id	sid	tid	token	lemma	pos
admet-442	1	1	the	the	DET
admet-442	1	2	function	function	NOUN
admet-442	1	3	and	and	CCONJ
admet-442	1	4	regulation	regulation	NOUN
admet-442	1	5	of	of	ADP
admet-442	1	6	pd	pd	PROPN
admet-442	1	7	-	-	PROPN
admet-442	1	8	l1	l1	PROPN
admet-442	1	9	in	in	ADP
admet-442	1	10	immunotherapy	immunotherapy	NOUN
admet-442	1	11	doi	doi	NOUN
admet-442	1	12	:	:	PUNCT
admet-442	1	13	10.5599	10.5599	NUM
admet-442	1	14	/	/	SYM
admet-442	1	15	admet.5.3.442	admet.5.3.442	NUM
admet-442	1	16	159	159	NUM
admet-442	1	17	admet	admet	X
admet-442	1	18	&	&	CCONJ
admet-442	1	19	dmpk	dmpk	PROPN
admet-442	1	20	5(3	5(3	NUM
admet-442	1	21	)	)	PUNCT
admet-442	1	22	(	(	PUNCT
admet-442	1	23	2017	2017	NUM
admet-442	1	24	)	)	PUNCT
admet-442	1	25	159	159	NUM
admet-442	1	26	-	-	SYM
admet-442	1	27	172	172	NUM
admet-442	1	28	;	;	PUNCT
admet-442	1	29	doi	doi	NOUN
admet-442	1	30	:	:	PUNCT
admet-442	1	31	http://dx.doi.org/10.5599/admet.5.3.442	http://dx.doi.org/10.5599/admet.5.3.442	PROPN
admet-442	1	32	open	open	ADJ
admet-442	1	33	access	access	NOUN
admet-442	1	34	:	:	PUNCT
admet-442	1	35	issn	issn	PROPN
admet-442	1	36	:	:	PUNCT
admet-442	1	37	1848	1848	NUM
admet-442	1	38	-	-	SYM
admet-442	1	39	7718	7718	NUM
admet-442	1	40	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-442	1	41	review	review	VERB
admet-442	1	42	the	the	DET
admet-442	1	43	function	function	NOUN
admet-442	1	44	and	and	CCONJ
admet-442	1	45	regulation	regulation	NOUN
admet-442	1	46	of	of	ADP
admet-442	1	47	pd	pd	PROPN
admet-442	1	48	-	-	PROPN
admet-442	1	49	l1	l1	PROPN
admet-442	1	50	in	in	ADP
admet-442	1	51	immunotherapy	immunotherapy	NOUN
admet-442	1	52	libin	libin	PROPN
admet-442	1	53	guo1	guo1	PROPN
admet-442	1	54	,	,	PUNCT
admet-442	1	55	yao	yao	PROPN
admet-442	1	56	lin2	lin2	PROPN
admet-442	1	57	and	and	CCONJ
admet-442	1	58	hang	hang	VERB
admet-442	1	59	fai	fai	X
admet-442	1	60	kwok1	kwok1	PROPN
admet-442	1	61	*	*	PROPN
admet-442	1	62	1	1	NUM
admet-442	1	63	faculty	faculty	NOUN
admet-442	1	64	of	of	ADP
admet-442	1	65	health	health	NOUN
admet-442	1	66	sciences	sciences	PROPN
admet-442	1	67	,	,	PUNCT
admet-442	1	68	university	university	NOUN
admet-442	1	69	of	of	ADP
admet-442	1	70	macau	macau	PROPN
admet-442	1	71	,	,	PUNCT
admet-442	1	72	macau	macau	PROPN
admet-442	1	73	sar	sar	PROPN
admet-442	1	74	2	2	NUM
admet-442	1	75	college	college	PROPN
admet-442	1	76	of	of	ADP
admet-442	1	77	life	life	NOUN
admet-442	1	78	sciences	sciences	PROPN
admet-442	1	79	,	,	PUNCT
admet-442	1	80	fujian	fujian	PROPN
admet-442	1	81	normal	normal	ADJ
admet-442	1	82	university	university	PROPN
admet-442	1	83	,	,	PUNCT
admet-442	1	84	fuzhou	fuzhou	PROPN
admet-442	1	85	,	,	PUNCT
admet-442	1	86	fujian	fujian	PROPN
admet-442	1	87	province	province	PROPN
admet-442	1	88	,	,	PUNCT
admet-442	1	89	china	china	PROPN
admet-442	1	90	*	*	PUNCT
admet-442	1	91	corresponding	correspond	VERB
admet-442	1	92	author	author	NOUN
admet-442	1	93	:	:	PUNCT
admet-442	1	94	e	e	NOUN
admet-442	1	95	-	-	NOUN
admet-442	1	96	mail	mail	NOUN
admet-442	1	97	:	:	PUNCT
admet-442	2	1	hfkwok@umac.mo	hfkwok@umac.mo	PROPN
admet-442	2	2	;	;	PUNCT
admet-442	2	3	tel	tel	PROPN
admet-442	2	4	.	.	PUNCT
admet-442	2	5	:	:	PUNCT
admet-442	3	1	+853	+853	NOUN
admet-442	3	2	8822	8822	NUM
admet-442	3	3	4991	4991	NUM
admet-442	3	4	;	;	PUNCT
admet-442	3	5	fax	fax	NOUN
admet-442	3	6	:	:	PUNCT
admet-442	3	7	+853	+853	NOUN
admet-442	3	8	8822	8822	NUM
admet-442	3	9	4991	4991	NUM
admet-442	3	10	received	receive	VERB
admet-442	3	11	:	:	PUNCT
admet-442	3	12	september	september	PROPN
admet-442	3	13	18	18	NUM
admet-442	3	14	,	,	PUNCT
admet-442	3	15	2017	2017	NUM
admet-442	3	16	;	;	PUNCT
admet-442	3	17	revised	revise	VERB
admet-442	3	18	:	:	PUNCT
admet-442	3	19	september	september	PROPN
admet-442	3	20	27	27	NUM
admet-442	3	21	,	,	PUNCT
admet-442	3	22	2017	2017	NUM
admet-442	3	23	;	;	PUNCT
admet-442	3	24	published	publish	VERB
admet-442	3	25	:	:	PUNCT
admet-442	3	26	september	september	PROPN
admet-442	3	27	29	29	NUM
admet-442	3	28	,	,	PUNCT
admet-442	3	29	2017	2017	NUM
admet-442	3	30	abstract	abstract	ADJ
admet-442	3	31	pd	pd	PROPN
admet-442	3	32	-	-	PUNCT
admet-442	3	33	l1	l1	PROPN
admet-442	3	34	,	,	PUNCT
admet-442	3	35	also	also	ADV
admet-442	3	36	known	know	VERB
admet-442	3	37	as	as	ADP
admet-442	3	38	b7	b7	PROPN
admet-442	3	39	-	-	PUNCT
admet-442	3	40	h1	h1	PROPN
admet-442	3	41	,	,	PUNCT
admet-442	3	42	is	be	AUX
admet-442	3	43	a	a	DET
admet-442	3	44	type	type	NOUN
admet-442	3	45	i	i	PRON
admet-442	3	46	transmembrane	transmembrane	ADJ
admet-442	3	47	protein	protein	NOUN
admet-442	3	48	,	,	PUNCT
admet-442	3	49	which	which	PRON
admet-442	3	50	is	be	AUX
admet-442	3	51	expressed	express	VERB
admet-442	3	52	in	in	ADP
admet-442	3	53	different	different	ADJ
admet-442	3	54	kinds	kind	NOUN
admet-442	3	55	of	of	ADP
admet-442	3	56	tumor	tumor	NOUN
admet-442	3	57	cells	cell	NOUN
admet-442	3	58	.	.	PUNCT
admet-442	4	1	it	it	PRON
admet-442	4	2	is	be	AUX
admet-442	4	3	correlated	correlate	VERB
admet-442	4	4	with	with	ADP
admet-442	4	5	poor	poor	ADJ
admet-442	4	6	clinical	clinical	ADJ
admet-442	4	7	outcome	outcome	NOUN
admet-442	4	8	of	of	ADP
admet-442	4	9	patients	patient	NOUN
admet-442	4	10	with	with	ADP
admet-442	4	11	various	various	ADJ
admet-442	4	12	types	type	NOUN
admet-442	4	13	of	of	ADP
admet-442	4	14	tumors	tumor	NOUN
admet-442	4	15	.	.	PUNCT
admet-442	5	1	pd	pd	PROPN
admet-442	5	2	-	-	PROPN
admet-442	5	3	l1	l1	PROPN
admet-442	5	4	can	can	AUX
admet-442	5	5	regulate	regulate	VERB
admet-442	5	6	tumor	tumor	NOUN
admet-442	5	7	microenvironment	microenvironment	NOUN
admet-442	5	8	or	or	CCONJ
admet-442	5	9	tumor	tumor	NOUN
admet-442	5	10	related	relate	VERB
admet-442	5	11	immune	immune	ADJ
admet-442	5	12	response	response	NOUN
admet-442	5	13	through	through	ADP
admet-442	5	14	suppressing	suppress	VERB
admet-442	5	15	t	t	NOUN
admet-442	5	16	cell	cell	NOUN
admet-442	5	17	or	or	CCONJ
admet-442	5	18	nk	nk	PROPN
admet-442	5	19	cell	cell	NOUN
admet-442	5	20	mediated	mediate	VERB
admet-442	5	21	immune	immune	ADJ
admet-442	5	22	response	response	NOUN
admet-442	5	23	.	.	PUNCT
admet-442	6	1	pd	pd	PROPN
admet-442	6	2	-	-	PUNCT
admet-442	6	3	l1	l1	PROPN
admet-442	6	4	expression	expression	NOUN
admet-442	6	5	is	be	AUX
admet-442	6	6	regulated	regulate	VERB
admet-442	6	7	by	by	ADP
admet-442	6	8	various	various	ADJ
admet-442	6	9	cytokines	cytokine	NOUN
admet-442	6	10	,	,	PUNCT
admet-442	6	11	such	such	ADJ
admet-442	6	12	as	as	ADP
admet-442	6	13	lps	lps	PROPN
admet-442	6	14	,	,	PUNCT
admet-442	6	15	gm	gm	PROPN
admet-442	6	16	-	-	PUNCT
admet-442	6	17	csf	csf	PROPN
admet-442	6	18	,	,	PUNCT
admet-442	6	19	il-4	il-4	PROPN
admet-442	6	20	,	,	PUNCT
admet-442	6	21	tgf	tgf	PROPN
admet-442	6	22	-	-	PUNCT
admet-442	6	23	β	β	PROPN
admet-442	6	24	,	,	PUNCT
admet-442	6	25	tnf	tnf	PROPN
admet-442	6	26	-	-	PUNCT
admet-442	6	27	α	α	PROPN
admet-442	6	28	.	.	PUNCT
admet-442	6	29	pd-1	pd-1	ADP
admet-442	6	30	and	and	CCONJ
admet-442	6	31	pd	pd	PROPN
admet-442	6	32	-	-	PROPN
admet-442	6	33	l1	l1	PROPN
admet-442	6	34	are	be	AUX
admet-442	6	35	the	the	DET
admet-442	6	36	members	member	NOUN
admet-442	6	37	of	of	ADP
admet-442	6	38	b7	b7	PROPN
admet-442	6	39	and	and	CCONJ
admet-442	6	40	cd28	cd28	PROPN
admet-442	6	41	superfamily	superfamily	NOUN
admet-442	6	42	,	,	PUNCT
admet-442	6	43	respectively	respectively	ADV
admet-442	6	44	.	.	PUNCT
admet-442	7	1	the	the	DET
admet-442	7	2	b7	b7	PROPN
admet-442	7	3	/	/	SYM
admet-442	7	4	cd28	cd28	PROPN
admet-442	7	5	interaction	interaction	NOUN
admet-442	7	6	plays	play	VERB
admet-442	7	7	a	a	DET
admet-442	7	8	central	central	ADJ
admet-442	7	9	role	role	NOUN
admet-442	7	10	in	in	ADP
admet-442	7	11	immune	immune	ADJ
admet-442	7	12	tolerance	tolerance	NOUN
admet-442	7	13	.	.	PUNCT
admet-442	8	1	pd	pd	PROPN
admet-442	8	2	-	-	PROPN
admet-442	8	3	l1	l1	PROPN
admet-442	8	4	can	can	AUX
admet-442	8	5	bind	bind	VERB
admet-442	8	6	to	to	ADP
admet-442	8	7	pd-1	pd-1	NOUN
admet-442	8	8	,	,	PUNCT
admet-442	8	9	which	which	PRON
admet-442	8	10	leads	lead	VERB
admet-442	8	11	to	to	ADP
admet-442	8	12	the	the	DET
admet-442	8	13	suppression	suppression	NOUN
admet-442	8	14	of	of	ADP
admet-442	8	15	lymphocyte	lymphocyte	ADJ
admet-442	8	16	activation	activation	NOUN
admet-442	8	17	and	and	CCONJ
admet-442	8	18	apoptosis	apoptosis	NOUN
admet-442	8	19	of	of	ADP
admet-442	8	20	lymphocytes	lymphocyte	NOUN
admet-442	8	21	.	.	PUNCT
admet-442	9	1	anti	anti	ADJ
admet-442	9	2	-	-	ADJ
admet-442	9	3	pd	pd	ADJ
admet-442	9	4	-	-	PUNCT
admet-442	9	5	l1	l1	PROPN
admet-442	9	6	therapy	therapy	NOUN
admet-442	9	7	is	be	AUX
admet-442	9	8	one	one	NUM
admet-442	9	9	of	of	ADP
admet-442	9	10	the	the	DET
admet-442	9	11	immunotherapies	immunotherapy	NOUN
admet-442	9	12	to	to	PART
admet-442	9	13	treat	treat	VERB
admet-442	9	14	cancer	cancer	NOUN
admet-442	9	15	(	(	PUNCT
admet-442	9	16	especially	especially	ADV
admet-442	9	17	solid	solid	ADJ
admet-442	9	18	tumor	tumor	NOUN
admet-442	9	19	)	)	PUNCT
admet-442	9	20	.	.	PUNCT
admet-442	10	1	pd	pd	PROPN
admet-442	10	2	-	-	PUNCT
admet-442	10	3	l1	l1	PROPN
admet-442	10	4	expression	expression	NOUN
admet-442	10	5	may	may	AUX
admet-442	10	6	be	be	AUX
admet-442	10	7	associated	associate	VERB
admet-442	10	8	with	with	ADP
admet-442	10	9	efficacy	efficacy	NOUN
admet-442	10	10	of	of	ADP
admet-442	10	11	anti	anti	ADJ
admet-442	10	12	pd-1	pd-1	ADJ
admet-442	10	13	/	/	SYM
admet-442	10	14	pd	pd	ADJ
admet-442	10	15	-	-	PROPN
admet-442	10	16	l1	l1	PROPN
admet-442	10	17	therapy	therapy	NOUN
admet-442	10	18	.	.	PUNCT
admet-442	11	1	in	in	ADP
admet-442	11	2	this	this	DET
admet-442	11	3	review	review	NOUN
admet-442	11	4	,	,	PUNCT
admet-442	11	5	we	we	PRON
admet-442	11	6	will	will	AUX
admet-442	11	7	focus	focus	VERB
admet-442	11	8	on	on	ADP
admet-442	11	9	the	the	DET
admet-442	11	10	regulation	regulation	NOUN
admet-442	11	11	mechanism	mechanism	NOUN
admet-442	11	12	of	of	ADP
admet-442	11	13	pd	pd	PROPN
admet-442	11	14	-	-	PROPN
admet-442	11	15	l1	l1	PROPN
admet-442	11	16	expression	expression	NOUN
admet-442	11	17	,	,	PUNCT
admet-442	11	18	and	and	CCONJ
admet-442	11	19	describe	describe	VERB
admet-442	11	20	the	the	DET
admet-442	11	21	role	role	NOUN
admet-442	11	22	of	of	ADP
admet-442	11	23	pd-1	pd-1	ADP
admet-442	11	24	/	/	SYM
admet-442	11	25	pd	pd	ADJ
admet-442	11	26	-	-	PROPN
admet-442	11	27	l1	l1	PROPN
admet-442	11	28	binding	bind	VERB
admet-442	11	29	on	on	ADP
admet-442	11	30	the	the	DET
admet-442	11	31	anti	anti	ADJ
admet-442	11	32	-	-	ADJ
admet-442	11	33	pd-1	pd-1	ADJ
admet-442	11	34	/	/	SYM
admet-442	11	35	pd	pd	ADJ
admet-442	11	36	-	-	PROPN
admet-442	11	37	l1	l1	PROPN
admet-442	11	38	therapy	therapy	NOUN
admet-442	11	39	.	.	PUNCT
admet-442	12	1	keywords	keyword	NOUN
admet-442	12	2	immune	immune	ADJ
admet-442	12	3	checkpoint	checkpoint	NOUN
admet-442	12	4	;	;	PUNCT
admet-442	12	5	pd	pd	PROPN
admet-442	12	6	-	-	PUNCT
admet-442	12	7	l1	l1	PROPN
admet-442	12	8	expression	expression	NOUN
admet-442	12	9	;	;	PUNCT
admet-442	12	10	signal	signal	ADJ
admet-442	12	11	pathway	pathway	NOUN
admet-442	12	12	;	;	PUNCT
admet-442	12	13	regulation	regulation	NOUN
admet-442	12	14	mechanism	mechanism	NOUN
admet-442	12	15	.	.	PUNCT
admet-442	13	1	introduction	introduction	NOUN
admet-442	13	2	cancer	cancer	NOUN
admet-442	13	3	is	be	AUX
admet-442	13	4	the	the	DET
admet-442	13	5	first	first	ADJ
admet-442	13	6	leading	lead	VERB
admet-442	13	7	cause	cause	NOUN
admet-442	13	8	of	of	ADP
admet-442	13	9	death	death	NOUN
admet-442	13	10	in	in	ADP
admet-442	13	11	china	china	PROPN
admet-442	13	12	and	and	CCONJ
admet-442	13	13	second	second	ADJ
admet-442	13	14	leading	leading	ADJ
admet-442	13	15	cause	cause	NOUN
admet-442	13	16	of	of	ADP
admet-442	13	17	death	death	NOUN
admet-442	13	18	in	in	ADP
admet-442	13	19	united	united	PROPN
admet-442	13	20	states	states	PROPN
admet-442	13	21	in	in	ADP
admet-442	13	22	recent	recent	ADJ
admet-442	13	23	years	year	NOUN
admet-442	14	1	[	[	X
admet-442	14	2	1	1	NUM
admet-442	14	3	,	,	PUNCT
admet-442	14	4	2	2	NUM
admet-442	14	5	]	]	PUNCT
admet-442	14	6	.	.	PUNCT
admet-442	15	1	although	although	SCONJ
admet-442	15	2	,	,	PUNCT
admet-442	15	3	the	the	DET
admet-442	15	4	cancer	cancer	NOUN
admet-442	15	5	death	death	NOUN
admet-442	15	6	rates	rate	NOUN
admet-442	15	7	have	have	AUX
admet-442	15	8	declined	decline	VERB
admet-442	15	9	over	over	ADP
admet-442	15	10	2	2	NUM
admet-442	15	11	decades	decade	NOUN
admet-442	15	12	,	,	PUNCT
admet-442	15	13	the	the	DET
admet-442	15	14	death	death	NOUN
admet-442	15	15	rates	rate	NOUN
admet-442	15	16	caused	cause	VERB
admet-442	15	17	by	by	ADP
admet-442	15	18	cancers	cancer	NOUN
admet-442	15	19	of	of	ADP
admet-442	15	20	uterine	uterine	ADJ
admet-442	15	21	corpus	corpu	NOUN
admet-442	15	22	and	and	CCONJ
admet-442	15	23	liver	liver	NOUN
admet-442	15	24	are	be	AUX
admet-442	15	25	still	still	ADV
admet-442	15	26	increasing	increase	VERB
admet-442	15	27	.	.	PUNCT
admet-442	16	1	it	it	PRON
admet-442	16	2	is	be	AUX
admet-442	16	3	estimated	estimate	VERB
admet-442	16	4	that	that	SCONJ
admet-442	16	5	by	by	ADP
admet-442	16	6	2030	2030	NUM
admet-442	16	7	about	about	ADV
admet-442	16	8	13–17	13–17	NUM
admet-442	16	9	million	million	NUM
admet-442	16	10	people	people	NOUN
admet-442	16	11	will	will	AUX
admet-442	16	12	die	die	VERB
admet-442	16	13	from	from	ADP
admet-442	16	14	cancer	cancer	NOUN
admet-442	17	1	[	[	X
admet-442	17	2	3	3	NUM
admet-442	17	3	]	]	PUNCT
admet-442	17	4	.	.	PUNCT
admet-442	18	1	cancer	cancer	NOUN
admet-442	18	2	is	be	AUX
admet-442	18	3	a	a	DET
admet-442	18	4	major	major	ADJ
admet-442	18	5	public	public	ADJ
admet-442	18	6	health	health	NOUN
admet-442	18	7	issue	issue	NOUN
admet-442	18	8	,	,	PUNCT
admet-442	18	9	and	and	CCONJ
admet-442	18	10	the	the	DET
admet-442	18	11	search	search	NOUN
admet-442	18	12	for	for	ADP
admet-442	18	13	advanced	advanced	ADJ
admet-442	18	14	detection	detection	NOUN
admet-442	18	15	methods	method	NOUN
admet-442	18	16	and	and	CCONJ
admet-442	18	17	novel	novel	ADJ
admet-442	18	18	treatments	treatment	NOUN
admet-442	18	19	are	be	AUX
admet-442	18	20	important	important	ADJ
admet-442	18	21	.	.	PUNCT
admet-442	19	1	cancer	cancer	NOUN
admet-442	19	2	treatments	treatment	NOUN
admet-442	19	3	include	include	VERB
admet-442	19	4	various	various	ADJ
admet-442	19	5	types	type	NOUN
admet-442	19	6	of	of	ADP
admet-442	19	7	therapies	therapy	NOUN
admet-442	19	8	,	,	PUNCT
admet-442	19	9	such	such	ADJ
admet-442	19	10	as	as	ADP
admet-442	19	11	surgery	surgery	NOUN
admet-442	19	12	,	,	PUNCT
admet-442	19	13	radiation	radiation	NOUN
admet-442	19	14	,	,	PUNCT
admet-442	19	15	chemotherapy	chemotherapy	NOUN
admet-442	19	16	,	,	PUNCT
admet-442	19	17	biological	biological	ADJ
admet-442	19	18	therapy	therapy	NOUN
admet-442	19	19	and	and	CCONJ
admet-442	19	20	targeted	target	VERB
admet-442	19	21	therapy	therapy	NOUN
admet-442	19	22	[	[	X
admet-442	19	23	4	4	NUM
admet-442	19	24	-	-	SYM
admet-442	19	25	8	8	NUM
admet-442	19	26	]	]	PUNCT
admet-442	19	27	.	.	PUNCT
admet-442	20	1	among	among	ADP
admet-442	20	2	these	these	DET
admet-442	20	3	therapies	therapy	NOUN
admet-442	20	4	,	,	PUNCT
admet-442	20	5	immunotherapy	immunotherapy	NOUN
admet-442	20	6	for	for	ADP
admet-442	20	7	cancer	cancer	NOUN
admet-442	20	8	has	have	AUX
admet-442	20	9	now	now	ADV
admet-442	20	10	become	become	VERB
admet-442	20	11	a	a	DET
admet-442	20	12	new	new	ADJ
admet-442	20	13	standard	standard	ADJ
admet-442	20	14	strategy	strategy	NOUN
admet-442	20	15	to	to	PART
admet-442	20	16	treat	treat	VERB
admet-442	20	17	cancer	cancer	NOUN
admet-442	20	18	.	.	PUNCT
admet-442	21	1	with	with	ADP
admet-442	21	2	the	the	DET
admet-442	21	3	approval	approval	NOUN
admet-442	21	4	of	of	ADP
admet-442	21	5	rituximab	rituximab	NOUN
admet-442	21	6	and	and	CCONJ
admet-442	21	7	trastuzumab	trastuzumab	NOUN
admet-442	21	8	,	,	PUNCT
admet-442	21	9	immunotherapy	immunotherapy	NOUN
admet-442	21	10	the	the	DET
admet-442	21	11	field	field	NOUN
admet-442	21	12	of	of	ADP
admet-442	21	13	cancer	cancer	NOUN
admet-442	21	14	therapy	therapy	NOUN
admet-442	21	15	changed	change	VERB
admet-442	21	16	considerably	considerably	ADV
admet-442	22	1	[	[	X
admet-442	22	2	9	9	NUM
admet-442	22	3	]	]	PUNCT
admet-442	22	4	.	.	PUNCT
admet-442	23	1	over	over	ADP
admet-442	23	2	recent	recent	ADJ
admet-442	23	3	decades	decade	NOUN
admet-442	23	4	,	,	PUNCT
admet-442	23	5	immunotherapy	immunotherapy	NOUN
admet-442	23	6	has	have	AUX
admet-442	23	7	been	be	AUX
admet-442	23	8	used	use	VERB
admet-442	23	9	for	for	ADP
admet-442	23	10	solid	solid	ADJ
admet-442	23	11	and	and	CCONJ
admet-442	23	12	hematological	hematological	ADJ
admet-442	23	13	malignances	malignance	NOUN
admet-442	23	14	treatment	treatment	NOUN
admet-442	23	15	[	[	X
admet-442	23	16	10	10	NUM
admet-442	23	17	]	]	PUNCT
admet-442	23	18	.	.	PUNCT
admet-442	24	1	there	there	PRON
admet-442	24	2	are	be	VERB
admet-442	24	3	several	several	ADJ
admet-442	24	4	types	type	NOUN
admet-442	24	5	of	of	ADP
admet-442	24	6	immunotherapy	immunotherapy	NOUN
admet-442	24	7	,	,	PUNCT
admet-442	24	8	including	include	VERB
admet-442	24	9	vaccines	vaccine	NOUN
admet-442	24	10	,	,	PUNCT
admet-442	24	11	monoclonal	monoclonal	NOUN
admet-442	24	12	antibodies	antibody	NOUN
admet-442	24	13	,	,	PUNCT
admet-442	24	14	t	t	PROPN
admet-442	24	15	cell	cell	NOUN
admet-442	24	16	therapy	therapy	NOUN
admet-442	24	17	,	,	PUNCT
admet-442	24	18	oncolytic	oncolytic	ADJ
admet-442	24	19	virus	virus	NOUN
admet-442	24	20	therapy	therapy	NOUN
admet-442	24	21	,	,	PUNCT
admet-442	24	22	non	non	ADJ
admet-442	24	23	-	-	ADJ
admet-442	24	24	specific	specific	ADJ
admet-442	24	25	immunotherapies	immunotherapy	NOUN
admet-442	24	26	[	[	X
admet-442	24	27	11	11	NUM
admet-442	24	28	-	-	SYM
admet-442	24	29	15	15	NUM
admet-442	24	30	]	]	PUNCT
admet-442	24	31	.	.	PUNCT
admet-442	25	1	as	as	ADP
admet-442	25	2	one	one	NUM
admet-442	25	3	of	of	ADP
admet-442	25	4	approaches	approach	NOUN
admet-442	25	5	of	of	ADP
admet-442	25	6	immunotherapy	immunotherapy	NOUN
admet-442	25	7	,	,	PUNCT
admet-442	25	8	antibody	antibody	NOUN
admet-442	25	9	-	-	PUNCT
admet-442	25	10	based	base	VERB
admet-442	25	11	cancer	cancer	NOUN
admet-442	25	12	therapy	therapy	NOUN
admet-442	25	13	employs	employ	VERB
admet-442	25	14	monoclonal	monoclonal	NOUN
admet-442	25	15	antibodies	antibody	NOUN
admet-442	25	16	targeting	target	VERB
admet-442	25	17	receptor	receptor	NOUN
admet-442	25	18	tyrosine	tyrosine	PROPN
admet-442	25	19	kinase	kinase	PROPN
admet-442	25	20	(	(	PUNCT
admet-442	25	21	rtks	rtks	PROPN
admet-442	25	22	)	)	PUNCT
admet-442	25	23	,	,	PUNCT
admet-442	25	24	immune	immune	ADJ
admet-442	25	25	checkpoint	checkpoint	NOUN
admet-442	25	26	inhibitor	inhibitor	NOUN
admet-442	25	27	,	,	PUNCT
admet-442	25	28	or	or	CCONJ
admet-442	25	29	other	other	ADJ
admet-442	25	30	membrane	membrane	NOUN
admet-442	25	31	antigens	antigen	NOUN
admet-442	25	32	.	.	PUNCT
admet-442	26	1	antibodies	antibodie	VERB
admet-442	26	2	targeting	target	VERB
admet-442	26	3	rtks	rtks	NOUN
admet-442	26	4	(	(	PUNCT
admet-442	26	5	such	such	ADJ
admet-442	26	6	as	as	ADP
admet-442	26	7	human	human	ADJ
admet-442	26	8	epidermal	epidermal	ADJ
admet-442	26	9	growth	growth	NOUN
admet-442	26	10	factor	factor	NOUN
admet-442	26	11	receptor	receptor	NOUN
admet-442	26	12	2	2	NUM
admet-442	26	13	(	(	PUNCT
admet-442	26	14	her2	her2	PROPN
admet-442	26	15	)	)	PUNCT
admet-442	26	16	and	and	CCONJ
admet-442	26	17	extracellular	extracellular	ADJ
admet-442	26	18	signal	signal	NOUN
admet-442	26	19	regulated	regulate	VERB
admet-442	26	20	kinase	kinase	PROPN
admet-442	26	21	(	(	PUNCT
admet-442	26	22	erk	erk	PROPN
admet-442	26	23	)	)	PUNCT
admet-442	26	24	)	)	PUNCT
admet-442	26	25	are	be	AUX
admet-442	26	26	often	often	ADV
admet-442	26	27	limited	limit	VERB
admet-442	26	28	by	by	ADP
admet-442	26	29	resistance	resistance	NOUN
admet-442	26	30	.	.	PUNCT
admet-442	27	1	for	for	ADP
admet-442	27	2	example	example	NOUN
admet-442	27	3	,	,	PUNCT
admet-442	27	4	colorectal	colorectal	ADJ
admet-442	27	5	cancer	cancer	NOUN
admet-442	27	6	patients	patient	NOUN
admet-442	27	7	are	be	AUX
admet-442	27	8	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-442	27	9	mailto:hfkwok@umac.mo	mailto:hfkwok@umac.mo	PROPN
admet-442	27	10	guo	guo	PROPN
admet-442	27	11	,	,	PUNCT
admet-442	27	12	lin	lin	PROPN
admet-442	27	13	and	and	CCONJ
admet-442	27	14	kwok	kwok	PROPN
admet-442	27	15	admet	admet	PROPN
admet-442	27	16	&	&	CCONJ
admet-442	27	17	dmpk	dmpk	PROPN
admet-442	27	18	5(3	5(3	NUM
admet-442	27	19	)	)	PUNCT
admet-442	27	20	(	(	PUNCT
admet-442	27	21	2017	2017	NUM
admet-442	27	22	)	)	PUNCT
admet-442	27	23	159	159	NUM
admet-442	27	24	-	-	SYM
admet-442	27	25	172	172	NUM
admet-442	27	26	160	160	NUM
admet-442	27	27	resistant	resistant	ADJ
admet-442	27	28	to	to	ADP
admet-442	27	29	cetuximab	cetuximab	NOUN
admet-442	27	30	and	and	CCONJ
admet-442	27	31	panitumumab	panitumumab	NOUN
admet-442	27	32	(	(	PUNCT
admet-442	27	33	antiepidermal	antiepidermal	ADJ
admet-442	27	34	growth	growth	NOUN
admet-442	27	35	factor	factor	NOUN
admet-442	27	36	receptor	receptor	NOUN
admet-442	27	37	(	(	PUNCT
admet-442	27	38	egfr	egfr	X
admet-442	27	39	)	)	PUNCT
admet-442	27	40	antibodies	antibodie	VERB
admet-442	27	41	)	)	PUNCT
admet-442	27	42	when	when	SCONJ
admet-442	27	43	the	the	DET
admet-442	27	44	tumor	tumor	NOUN
admet-442	27	45	has	have	VERB
admet-442	27	46	a	a	DET
admet-442	27	47	mutated	mutate	VERB
admet-442	27	48	ras	ras	NOUN
admet-442	27	49	-	-	NOUN
admet-442	27	50	protein	protein	NOUN
admet-442	27	51	[	[	X
admet-442	27	52	16	16	NUM
admet-442	27	53	,	,	PUNCT
admet-442	27	54	17	17	NUM
admet-442	27	55	]	]	PUNCT
admet-442	27	56	.	.	PUNCT
admet-442	28	1	bispecific	bispecific	PROPN
admet-442	28	2	antibodies	antibodie	VERB
admet-442	28	3	(	(	PUNCT
admet-442	28	4	bsab	bsab	NOUN
admet-442	28	5	)	)	PUNCT
admet-442	28	6	and	and	CCONJ
admet-442	28	7	homo	homo	NOUN
admet-442	28	8	-	-	PUNCT
admet-442	28	9	combinations	combination	NOUN
admet-442	28	10	of	of	ADP
admet-442	28	11	antibodies	antibody	NOUN
admet-442	28	12	targeting	target	VERB
admet-442	28	13	rtks	rtks	NOUN
admet-442	28	14	are	be	AUX
admet-442	28	15	employed	employ	VERB
admet-442	28	16	to	to	PART
admet-442	28	17	improve	improve	VERB
admet-442	28	18	sensitivity	sensitivity	NOUN
admet-442	28	19	of	of	ADP
admet-442	28	20	patients	patient	NOUN
admet-442	28	21	to	to	ADP
admet-442	28	22	antibodies[18	antibodies[18	ADV
admet-442	28	23	]	]	PUNCT
admet-442	28	24	.	.	PUNCT
admet-442	29	1	immune	immune	ADJ
admet-442	29	2	checkpoint	checkpoint	NOUN
admet-442	29	3	inhibitor	inhibitor	NOUN
admet-442	29	4	,	,	PUNCT
admet-442	29	5	such	such	ADJ
admet-442	29	6	as	as	ADP
admet-442	29	7	anti	anti	ADJ
admet-442	29	8	-	-	ADJ
admet-442	29	9	programmed	programmed	ADJ
admet-442	29	10	cell	cell	NOUN
admet-442	29	11	death	death	NOUN
admet-442	29	12	protein	protein	NOUN
admet-442	29	13	1	1	NUM
admet-442	29	14	(	(	PUNCT
admet-442	29	15	pd-1	pd-1	ADV
admet-442	29	16	)	)	PUNCT
admet-442	29	17	antibody	antibody	NOUN
admet-442	29	18	,	,	PUNCT
admet-442	29	19	anti	anti	ADJ
admet-442	29	20	-	-	ADJ
admet-442	29	21	programmed	programmed	ADJ
admet-442	29	22	death	death	NOUN
admet-442	29	23	ligand	ligand	NOUN
admet-442	29	24	1	1	NUM
admet-442	29	25	(	(	PUNCT
admet-442	29	26	pd	pd	NOUN
admet-442	29	27	-	-	PUNCT
admet-442	29	28	l1	l1	NOUN
admet-442	29	29	)	)	PUNCT
admet-442	29	30	antibody	antibody	NOUN
admet-442	29	31	and	and	CCONJ
admet-442	29	32	anti	anti	ADJ
admet-442	29	33	-	-	ADJ
admet-442	29	34	cytotoxic	cytotoxic	ADJ
admet-442	29	35	t	t	NOUN
admet-442	29	36	-	-	PUNCT
admet-442	29	37	lymphocyte	lymphocyte	NOUN
admet-442	29	38	-	-	PUNCT
admet-442	29	39	associated	associate	VERB
admet-442	29	40	protein	protein	NOUN
admet-442	29	41	4	4	NUM
admet-442	29	42	(	(	PUNCT
admet-442	29	43	ctla-4	ctla-4	NOUN
admet-442	29	44	)	)	PUNCT
admet-442	29	45	antibody	antibody	NOUN
admet-442	29	46	,	,	PUNCT
admet-442	29	47	can	can	AUX
admet-442	29	48	enhance	enhance	VERB
admet-442	29	49	the	the	DET
admet-442	29	50	ability	ability	NOUN
admet-442	29	51	of	of	ADP
admet-442	29	52	cytotoxic	cytotoxic	ADJ
admet-442	29	53	t	t	NOUN
admet-442	29	54	cells	cell	NOUN
admet-442	29	55	to	to	PART
admet-442	29	56	recognize	recognize	VERB
admet-442	29	57	tumor	tumor	NOUN
admet-442	29	58	without	without	ADP
admet-442	29	59	limitation	limitation	NOUN
admet-442	29	60	by	by	ADP
admet-442	29	61	resistance	resistance	NOUN
admet-442	29	62	[	[	X
admet-442	29	63	19	19	NUM
admet-442	29	64	]	]	PUNCT
admet-442	29	65	.	.	PUNCT
admet-442	30	1	pd	pd	PROPN
admet-442	30	2	-	-	PROPN
admet-442	30	3	l1	l1	PROPN
admet-442	30	4	is	be	AUX
admet-442	30	5	known	know	VERB
admet-442	30	6	as	as	ADP
admet-442	30	7	b7	b7	PROPN
admet-442	30	8	homolog	homolog	PROPN
admet-442	30	9	1	1	NUM
admet-442	30	10	(	(	PUNCT
admet-442	30	11	b7	b7	PROPN
admet-442	30	12	-	-	PUNCT
admet-442	30	13	h1	h1	PROPN
admet-442	30	14	)	)	PUNCT
admet-442	30	15	or	or	CCONJ
admet-442	30	16	cluster	cluster	NOUN
admet-442	30	17	of	of	ADP
admet-442	30	18	differentiation	differentiation	NOUN
admet-442	30	19	(	(	PUNCT
admet-442	30	20	cd274	cd274	NOUN
admet-442	30	21	)	)	PUNCT
admet-442	30	22	and	and	CCONJ
admet-442	30	23	is	be	AUX
admet-442	30	24	recognized	recognize	VERB
admet-442	30	25	as	as	ADP
admet-442	30	26	a	a	DET
admet-442	30	27	cell	cell	NOUN
admet-442	30	28	surface	surface	NOUN
admet-442	30	29	protein	protein	NOUN
admet-442	30	30	belonging	belong	VERB
admet-442	30	31	to	to	ADP
admet-442	30	32	b7	b7	PROPN
admet-442	30	33	superfamily	superfamily	ADV
admet-442	30	34	.	.	PUNCT
admet-442	31	1	many	many	ADJ
admet-442	31	2	studies	study	NOUN
admet-442	31	3	have	have	AUX
admet-442	31	4	reported	report	VERB
admet-442	31	5	that	that	SCONJ
admet-442	31	6	pd	pd	PROPN
admet-442	31	7	-	-	PROPN
admet-442	31	8	l1	l1	PROPN
admet-442	31	9	can	can	AUX
admet-442	31	10	suppress	suppress	VERB
admet-442	31	11	t	t	NOUN
admet-442	31	12	lymphocyte	lymphocyte	ADJ
admet-442	31	13	activation	activation	NOUN
admet-442	31	14	through	through	ADP
admet-442	31	15	interacting	interact	VERB
admet-442	31	16	with	with	ADP
admet-442	31	17	some	some	DET
admet-442	31	18	pd	pd	PROPN
admet-442	31	19	-	-	PUNCT
admet-442	31	20	l1	l1	PROPN
admet-442	31	21	receptor	receptor	NOUN
admet-442	31	22	,	,	PUNCT
admet-442	31	23	such	such	ADJ
admet-442	31	24	as	as	ADP
admet-442	31	25	pd-1	pd-1	ADJ
admet-442	31	26	.	.	PUNCT
admet-442	31	27	pd	pd	PROPN
admet-442	31	28	-	-	PUNCT
admet-442	31	29	l1	l1	PROPN
admet-442	31	30	directed	direct	VERB
admet-442	31	31	therapy	therapy	NOUN
admet-442	31	32	of	of	ADP
admet-442	31	33	cancer	cancer	NOUN
admet-442	31	34	many	many	ADJ
admet-442	31	35	studies	study	NOUN
admet-442	31	36	showed	show	VERB
admet-442	31	37	that	that	SCONJ
admet-442	31	38	pd	pd	PROPN
admet-442	31	39	-	-	PUNCT
admet-442	31	40	l1	l1	PROPN
admet-442	31	41	expression	expression	NOUN
admet-442	31	42	is	be	AUX
admet-442	31	43	present	present	ADJ
admet-442	31	44	in	in	ADP
admet-442	31	45	various	various	ADJ
admet-442	31	46	kinds	kind	NOUN
admet-442	31	47	of	of	ADP
admet-442	31	48	tumors	tumor	NOUN
admet-442	31	49	,	,	PUNCT
admet-442	31	50	which	which	PRON
admet-442	31	51	suggested	suggest	VERB
admet-442	31	52	that	that	SCONJ
admet-442	31	53	pd	pd	PROPN
admet-442	31	54	-	-	PROPN
admet-442	31	55	l1	l1	PROPN
admet-442	31	56	may	may	AUX
admet-442	31	57	be	be	AUX
admet-442	31	58	closely	closely	ADV
admet-442	31	59	related	relate	VERB
admet-442	31	60	with	with	ADP
admet-442	31	61	cancer	cancer	NOUN
admet-442	31	62	.	.	PUNCT
admet-442	32	1	liu	liu	PROPN
admet-442	32	2	et	et	PROPN
admet-442	32	3	al	al	PROPN
admet-442	32	4	.	.	PROPN
admet-442	32	5	demonstrated	demonstrate	VERB
admet-442	32	6	that	that	SCONJ
admet-442	32	7	pd	pd	PROPN
admet-442	32	8	-	-	PUNCT
admet-442	32	9	l1	l1	PROPN
admet-442	32	10	expression	expression	NOUN
admet-442	32	11	was	be	AUX
admet-442	32	12	found	find	VERB
admet-442	32	13	in	in	ADP
admet-442	32	14	multiple	multiple	ADJ
admet-442	32	15	myeloma	myeloma	NOUN
admet-442	32	16	plasma	plasma	NOUN
admet-442	32	17	cells	cell	NOUN
admet-442	32	18	,	,	PUNCT
admet-442	32	19	but	but	CCONJ
admet-442	32	20	not	not	PART
admet-442	32	21	in	in	ADP
admet-442	32	22	cells	cell	NOUN
admet-442	32	23	which	which	PRON
admet-442	32	24	were	be	AUX
admet-442	32	25	isolated	isolate	VERB
admet-442	32	26	from	from	ADP
admet-442	32	27	monoclonal	monoclonal	NOUN
admet-442	32	28	gammopathy	gammopathy	ADJ
admet-442	32	29	or	or	CCONJ
admet-442	32	30	healthy	healthy	ADJ
admet-442	32	31	donors	donor	NOUN
admet-442	32	32	[	[	X
admet-442	32	33	20	20	NUM
admet-442	32	34	]	]	PUNCT
admet-442	32	35	.	.	PUNCT
admet-442	33	1	pd	pd	PROPN
admet-442	33	2	-	-	PUNCT
admet-442	33	3	l1	l1	PROPN
admet-442	33	4	expression	expression	NOUN
admet-442	33	5	has	have	AUX
admet-442	33	6	not	not	PART
admet-442	33	7	only	only	ADV
admet-442	33	8	been	be	AUX
admet-442	33	9	found	find	VERB
admet-442	33	10	on	on	ADP
admet-442	33	11	glial	glial	ADJ
admet-442	33	12	tumor	tumor	NOUN
admet-442	33	13	cells	cell	NOUN
admet-442	33	14	,	,	PUNCT
admet-442	33	15	but	but	CCONJ
admet-442	33	16	also	also	ADV
admet-442	33	17	on	on	ADP
admet-442	33	18	various	various	ADJ
admet-442	33	19	brain	brain	NOUN
admet-442	33	20	metastases	metastasis	NOUN
admet-442	33	21	[	[	X
admet-442	33	22	21	21	NUM
admet-442	33	23	,	,	PUNCT
admet-442	33	24	22	22	NUM
admet-442	33	25	]	]	PUNCT
admet-442	33	26	.	.	PUNCT
admet-442	34	1	66	66	NUM
admet-442	34	2	%	%	NOUN
admet-442	34	3	of	of	ADP
admet-442	34	4	freshly	freshly	ADV
admet-442	34	5	isolated	isolate	VERB
admet-442	34	6	head	head	NOUN
admet-442	34	7	and	and	CCONJ
admet-442	34	8	neck	neck	NOUN
admet-442	34	9	squamous	squamous	ADJ
admet-442	34	10	cell	cell	NOUN
admet-442	34	11	carcinoma	carcinoma	NOUN
admet-442	34	12	(	(	PUNCT
admet-442	34	13	hnscc	hnscc	NOUN
admet-442	34	14	)	)	PUNCT
admet-442	34	15	showed	show	VERB
admet-442	34	16	constitutive	constitutive	ADJ
admet-442	34	17	expression	expression	NOUN
admet-442	34	18	of	of	ADP
admet-442	34	19	pd	pd	PROPN
admet-442	34	20	-	-	PROPN
admet-442	34	21	l1	l1	PROPN
admet-442	34	22	[	[	X
admet-442	34	23	23	23	NUM
admet-442	34	24	]	]	PUNCT
admet-442	34	25	.	.	PUNCT
admet-442	35	1	except	except	SCONJ
admet-442	35	2	for	for	ADP
admet-442	35	3	cancers	cancer	NOUN
admet-442	35	4	mentioned	mention	VERB
admet-442	35	5	above	above	ADV
admet-442	35	6	,	,	PUNCT
admet-442	35	7	upregulation	upregulation	NOUN
admet-442	35	8	of	of	ADP
admet-442	35	9	pd	pd	PROPN
admet-442	35	10	-	-	PROPN
admet-442	35	11	l1	l1	PROPN
admet-442	35	12	has	have	AUX
admet-442	35	13	also	also	ADV
admet-442	35	14	been	be	AUX
admet-442	35	15	found	find	VERB
admet-442	35	16	in	in	ADP
admet-442	35	17	other	other	ADJ
admet-442	35	18	common	common	ADJ
admet-442	35	19	cancers	cancer	NOUN
admet-442	35	20	,	,	PUNCT
admet-442	35	21	such	such	ADJ
admet-442	35	22	as	as	ADP
admet-442	35	23	melanoma	melanoma	NOUN
admet-442	35	24	,	,	PUNCT
admet-442	35	25	ovarian	ovarian	ADJ
admet-442	35	26	cancer	cancer	NOUN
admet-442	35	27	,	,	PUNCT
admet-442	35	28	lung	lung	NOUN
admet-442	35	29	cancer	cancer	NOUN
admet-442	35	30	,	,	PUNCT
admet-442	35	31	urothelial	urothelial	ADJ
admet-442	35	32	carcinoma	carcinoma	NOUN
admet-442	35	33	,	,	PUNCT
admet-442	35	34	esophageal	esophageal	ADJ
admet-442	35	35	cancer	cancer	NOUN
admet-442	35	36	,	,	PUNCT
admet-442	35	37	cervical	cervical	ADJ
admet-442	35	38	cancer	cancer	NOUN
admet-442	35	39	,	,	PUNCT
admet-442	35	40	pancreatic	pancreatic	ADJ
admet-442	35	41	cancer	cancer	NOUN
admet-442	35	42	and	and	CCONJ
admet-442	35	43	wilms	wilm	NOUN
admet-442	35	44	tumor	tumor	NOUN
admet-442	36	1	[	[	X
admet-442	36	2	24	24	NUM
admet-442	36	3	-	-	SYM
admet-442	36	4	31	31	NUM
admet-442	36	5	]	]	PUNCT
admet-442	36	6	.	.	PUNCT
admet-442	37	1	recent	recent	ADJ
admet-442	37	2	clinical	clinical	ADJ
admet-442	37	3	data	datum	NOUN
admet-442	37	4	showed	show	VERB
admet-442	37	5	that	that	SCONJ
admet-442	37	6	increased	increase	VERB
admet-442	37	7	expression	expression	NOUN
admet-442	37	8	of	of	ADP
admet-442	37	9	pd	pd	PROPN
admet-442	37	10	-	-	PROPN
admet-442	37	11	l1	l1	PROPN
admet-442	37	12	was	be	AUX
admet-442	37	13	closely	closely	ADV
admet-442	37	14	related	relate	VERB
admet-442	37	15	with	with	ADP
admet-442	37	16	a	a	DET
admet-442	37	17	poor	poor	ADJ
admet-442	37	18	prognosis	prognosis	NOUN
admet-442	37	19	in	in	ADP
admet-442	37	20	chronic	chronic	ADJ
admet-442	37	21	hepatitis	hepatitis	PROPN
admet-442	37	22	b	b	PROPN
admet-442	37	23	virus	virus	NOUN
admet-442	37	24	(	(	PUNCT
admet-442	37	25	hbv	hbv	NOUN
admet-442	37	26	)	)	PUNCT
admet-442	37	27	infected	infect	VERB
admet-442	37	28	hepatocellular	hepatocellular	ADJ
admet-442	37	29	carcinoma	carcinoma	NOUN
admet-442	37	30	patients	patient	NOUN
admet-442	37	31	[	[	X
admet-442	37	32	32	32	NUM
admet-442	37	33	]	]	PUNCT
admet-442	37	34	.	.	PUNCT
admet-442	38	1	in	in	ADP
admet-442	38	2	breast	breast	NOUN
admet-442	38	3	cancers	cancer	NOUN
admet-442	38	4	it	it	PRON
admet-442	38	5	was	be	AUX
admet-442	38	6	shown	show	VERB
admet-442	38	7	that	that	SCONJ
admet-442	38	8	in	in	ADP
admet-442	38	9	this	this	DET
admet-442	38	10	disease	disease	NOUN
admet-442	38	11	a	a	DET
admet-442	38	12	higher	high	ADJ
admet-442	38	13	expression	expression	NOUN
admet-442	38	14	of	of	ADP
admet-442	38	15	pd	pd	PROPN
admet-442	38	16	-	-	PROPN
admet-442	38	17	l1	l1	PROPN
admet-442	38	18	had	have	VERB
admet-442	38	19	a	a	DET
admet-442	38	20	strong	strong	ADJ
admet-442	38	21	link	link	NOUN
admet-442	38	22	with	with	ADP
admet-442	38	23	several	several	ADJ
admet-442	38	24	characteristics	characteristic	NOUN
admet-442	38	25	,	,	PUNCT
admet-442	38	26	such	such	ADJ
admet-442	38	27	as	as	ADP
admet-442	38	28	tumor	tumor	NOUN
admet-442	38	29	size	size	NOUN
admet-442	38	30	,	,	PUNCT
admet-442	38	31	american	american	PROPN
admet-442	38	32	joint	joint	PROPN
admet-442	38	33	committee	committee	PROPN
admet-442	38	34	on	on	ADP
admet-442	38	35	cancer	cancer	NOUN
admet-442	38	36	(	(	PUNCT
admet-442	38	37	ajcc	ajcc	PROPN
admet-442	38	38	)	)	PUNCT
admet-442	38	39	primary	primary	ADJ
admet-442	38	40	tumor	tumor	NOUN
admet-442	38	41	classification	classification	NOUN
admet-442	38	42	,	,	PUNCT
admet-442	38	43	tumor	tumor	NOUN
admet-442	38	44	grade	grade	NOUN
admet-442	38	45	,	,	PUNCT
admet-442	38	46	lymph	lymph	NOUN
admet-442	38	47	node	node	ADJ
admet-442	38	48	status	status	NOUN
admet-442	38	49	,	,	PUNCT
admet-442	38	50	and	and	CCONJ
admet-442	38	51	high	high	ADJ
admet-442	38	52	ki-67	ki-67	ADJ
admet-442	38	53	expression	expression	NOUN
admet-442	38	54	[	[	X
admet-442	38	55	33	33	NUM
admet-442	38	56	]	]	PUNCT
admet-442	38	57	.	.	PUNCT
admet-442	39	1	meanwhile	meanwhile	ADV
admet-442	39	2	,	,	PUNCT
admet-442	39	3	pd	pd	PROPN
admet-442	39	4	-	-	PROPN
admet-442	39	5	l1	l1	PROPN
admet-442	39	6	was	be	AUX
admet-442	39	7	also	also	ADV
admet-442	39	8	shown	show	VERB
admet-442	39	9	to	to	PART
admet-442	39	10	be	be	AUX
admet-442	39	11	related	relate	VERB
admet-442	39	12	to	to	ADP
admet-442	39	13	poor	poor	ADJ
admet-442	39	14	prognosis	prognosis	NOUN
admet-442	39	15	in	in	ADP
admet-442	39	16	human	human	ADJ
admet-442	39	17	breast	breast	NOUN
admet-442	39	18	cancer	cancer	NOUN
admet-442	40	1	[	[	X
admet-442	40	2	33	33	NUM
admet-442	40	3	]	]	PUNCT
admet-442	40	4	.	.	PUNCT
admet-442	41	1	upregulation	upregulation	NOUN
admet-442	41	2	of	of	ADP
admet-442	41	3	pd	pd	PROPN
admet-442	41	4	-	-	PROPN
admet-442	41	5	l1	l1	PROPN
admet-442	41	6	was	be	AUX
admet-442	41	7	closely	closely	ADV
admet-442	41	8	related	relate	VERB
admet-442	41	9	with	with	ADP
admet-442	41	10	late	late	ADJ
admet-442	41	11	stage	stage	NOUN
admet-442	41	12	clinical	clinical	ADJ
admet-442	41	13	development	development	NOUN
admet-442	41	14	and	and	CCONJ
admet-442	41	15	decreased	decrease	VERB
admet-442	41	16	rate	rate	NOUN
admet-442	41	17	of	of	ADP
admet-442	41	18	disease	disease	NOUN
admet-442	41	19	-	-	PUNCT
admet-442	41	20	free	free	ADJ
admet-442	41	21	survival	survival	NOUN
admet-442	42	1	[	[	X
admet-442	42	2	34	34	NUM
admet-442	42	3	]	]	PUNCT
admet-442	42	4	.	.	PUNCT
admet-442	43	1	sarah	sarah	PROPN
admet-442	43	2	et	et	PROPN
admet-442	43	3	al	al	PROPN
admet-442	43	4	.	.	PROPN
admet-442	43	5	reported	report	VERB
admet-442	43	6	that	that	SCONJ
admet-442	43	7	pd	pd	PROPN
admet-442	43	8	-	-	PROPN
admet-442	43	9	l1	l1	PROPN
admet-442	43	10	was	be	AUX
admet-442	43	11	expressed	express	VERB
admet-442	43	12	in	in	ADP
admet-442	43	13	tumor	tumor	NOUN
admet-442	43	14	cells	cell	NOUN
admet-442	43	15	of	of	ADP
admet-442	43	16	patients	patient	NOUN
admet-442	43	17	with	with	ADP
admet-442	43	18	epstein	epstein	PROPN
admet-442	43	19	-	-	PUNCT
admet-442	43	20	barr	barr	PROPN
admet-442	43	21	virus	virus	PROPN
admet-442	43	22	(	(	PUNCT
admet-442	43	23	ebv	ebv	NOUN
admet-442	43	24	)	)	PUNCT
admet-442	43	25	infected	infect	VERB
admet-442	43	26	gastric	gastric	ADJ
admet-442	43	27	cancer	cancer	NOUN
admet-442	43	28	(	(	PUNCT
admet-442	43	29	gc	gc	PROPN
admet-442	43	30	)	)	PUNCT
admet-442	43	31	,	,	PUNCT
admet-442	43	32	but	but	CCONJ
admet-442	43	33	not	not	PART
admet-442	43	34	in	in	ADP
admet-442	43	35	other	other	ADJ
admet-442	43	36	gc	gc	PROPN
admet-442	43	37	cancer	cancer	NOUN
admet-442	43	38	cells	cell	NOUN
admet-442	43	39	[	[	X
admet-442	43	40	35	35	NUM
admet-442	43	41	]	]	PUNCT
admet-442	43	42	.	.	PUNCT
admet-442	44	1	besides	besides	SCONJ
admet-442	44	2	,	,	PUNCT
admet-442	44	3	preclinical	preclinical	ADJ
admet-442	44	4	experiments	experiment	NOUN
admet-442	44	5	also	also	ADV
admet-442	44	6	showed	show	VERB
admet-442	44	7	an	an	DET
admet-442	44	8	effect	effect	NOUN
admet-442	44	9	of	of	ADP
admet-442	44	10	pd	pd	PROPN
admet-442	44	11	-	-	PROPN
admet-442	44	12	l1	l1	PROPN
admet-442	44	13	on	on	ADP
admet-442	44	14	tumor	tumor	NOUN
admet-442	44	15	treatment	treatment	NOUN
admet-442	44	16	.	.	PUNCT
admet-442	45	1	in	in	ADP
admet-442	45	2	an	an	DET
admet-442	45	3	acute	acute	ADJ
admet-442	45	4	myeloid	myeloid	NOUN
admet-442	45	5	leukemia	leukemia	NOUN
admet-442	45	6	(	(	PUNCT
admet-442	45	7	aml	aml	PROPN
admet-442	45	8	)	)	PUNCT
admet-442	45	9	model	model	NOUN
admet-442	45	10	,	,	PUNCT
admet-442	45	11	blockade	blockade	NOUN
admet-442	45	12	of	of	ADP
admet-442	45	13	pd	pd	PROPN
admet-442	45	14	-	-	PROPN
admet-442	45	15	l1	l1	PROPN
admet-442	45	16	by	by	ADP
admet-442	45	17	antibodies	antibody	NOUN
admet-442	45	18	enhanced	enhance	VERB
admet-442	45	19	immune	immune	ADJ
admet-442	45	20	response	response	NOUN
admet-442	45	21	against	against	ADP
admet-442	45	22	leukemia	leukemia	NOUN
admet-442	45	23	cells	cell	NOUN
admet-442	45	24	(	(	PUNCT
admet-442	45	25	c1498.gfp	c1498.gfp	NOUN
admet-442	45	26	cells	cell	NOUN
admet-442	45	27	)	)	PUNCT
admet-442	45	28	in	in	ADP
admet-442	45	29	c57bl/6	c57bl/6	NOUN
admet-442	45	30	mice	mouse	NOUN
admet-442	45	31	[	[	X
admet-442	45	32	36	36	NUM
admet-442	45	33	]	]	PUNCT
admet-442	45	34	.	.	PUNCT
admet-442	46	1	meanwhile	meanwhile	ADV
admet-442	46	2	,	,	PUNCT
admet-442	46	3	cd8	cd8	PROPN
admet-442	46	4	+	+	PROPN
admet-442	46	5	t	t	NOUN
admet-442	46	6	cell	cell	NOUN
admet-442	46	7	receiving	receive	VERB
admet-442	46	8	anti	anti	ADJ
admet-442	46	9	-	-	ADJ
admet-442	46	10	pd	pd	ADJ
admet-442	46	11	-	-	PUNCT
admet-442	46	12	l1	l1	PROPN
admet-442	46	13	antibody	antibody	NOUN
admet-442	46	14	was	be	AUX
admet-442	46	15	shown	show	VERB
admet-442	46	16	to	to	PART
admet-442	46	17	increase	increase	VERB
admet-442	46	18	in	in	ADP
admet-442	46	19	livers	liver	NOUN
admet-442	46	20	from	from	ADP
admet-442	46	21	c57bl/6	c57bl/6	NOUN
admet-442	46	22	mice	mouse	NOUN
admet-442	46	23	compared	compare	VERB
admet-442	46	24	to	to	ADP
admet-442	46	25	control	control	VERB
admet-442	46	26	without	without	ADP
admet-442	46	27	treatment	treatment	NOUN
admet-442	46	28	with	with	ADP
admet-442	46	29	antibodies	antibody	NOUN
admet-442	46	30	[	[	X
admet-442	46	31	36	36	NUM
admet-442	46	32	]	]	PUNCT
admet-442	46	33	.	.	PUNCT
admet-442	47	1	iwai	iwai	PROPN
admet-442	47	2	et	et	PROPN
admet-442	47	3	al	al	PROPN
admet-442	47	4	.	.	PROPN
admet-442	47	5	showed	show	VERB
admet-442	47	6	that	that	SCONJ
admet-442	47	7	in	in	ADP
admet-442	47	8	vitro	vitro	X
admet-442	47	9	p815	p815	PROPN
admet-442	47	10	cells	cell	NOUN
admet-442	47	11	transfected	transfecte	VERB
admet-442	47	12	with	with	ADP
admet-442	47	13	papuroxs	papuroxs	PROPN
admet-442	47	14	-	-	PUNCT
admet-442	47	15	pd	pd	NOUN
admet-442	47	16	-	-	PUNCT
admet-442	47	17	l1	l1	PROPN
admet-442	47	18	stably	stably	ADV
admet-442	47	19	expressed	express	VERB
admet-442	47	20	pd	pd	PROPN
admet-442	47	21	-	-	NOUN
admet-442	47	22	l1	l1	PROPN
admet-442	47	23	,	,	PUNCT
admet-442	47	24	and	and	CCONJ
admet-442	47	25	was	be	AUX
admet-442	47	26	susceptible	susceptible	ADJ
admet-442	47	27	to	to	ADP
admet-442	47	28	t	t	PROPN
admet-442	47	29	cell	cell	NOUN
admet-442	47	30	antigen	antigen	ADJ
admet-442	47	31	receptor	receptor	NOUN
admet-442	47	32	(	(	PUNCT
admet-442	47	33	tcr)-mediated	tcr)-mediated	ADJ
admet-442	47	34	lysis	lysis	NOUN
admet-442	47	35	induced	induce	VERB
admet-442	47	36	by	by	ADP
admet-442	47	37	cytotoxic	cytotoxic	ADJ
admet-442	47	38	t	t	NOUN
admet-442	47	39	cells	cell	NOUN
admet-442	47	40	[	[	X
admet-442	47	41	37	37	NUM
admet-442	47	42	]	]	PUNCT
admet-442	47	43	.	.	PUNCT
admet-442	48	1	most	most	ADV
admet-442	48	2	importantly	importantly	ADV
admet-442	48	3	,	,	PUNCT
admet-442	48	4	tumorigenesis	tumorigenesis	NOUN
admet-442	48	5	and	and	CCONJ
admet-442	48	6	invasiveness	invasiveness	NOUN
admet-442	48	7	of	of	ADP
admet-442	48	8	these	these	DET
admet-442	48	9	tumor	tumor	NOUN
admet-442	48	10	cells	cell	NOUN
admet-442	48	11	was	be	AUX
admet-442	48	12	enhanced	enhance	VERB
admet-442	48	13	compared	compare	VERB
admet-442	48	14	to	to	ADP
admet-442	48	15	parental	parental	ADJ
admet-442	48	16	cells	cell	NOUN
admet-442	48	17	which	which	PRON
admet-442	48	18	did	do	AUX
admet-442	48	19	n’t	not	PART
admet-442	48	20	express	express	VERB
admet-442	48	21	pd	pd	NOUN
admet-442	48	22	-	-	PROPN
admet-442	48	23	l1	l1	PROPN
admet-442	49	1	[	[	X
admet-442	49	2	37	37	NUM
admet-442	49	3	]	]	PUNCT
admet-442	49	4	.	.	PUNCT
admet-442	50	1	the	the	DET
admet-442	50	2	promoting	promote	VERB
admet-442	50	3	effect	effect	NOUN
admet-442	50	4	of	of	ADP
admet-442	50	5	pd	pd	PROPN
admet-442	50	6	-	-	PROPN
admet-442	50	7	l1	l1	PROPN
admet-442	50	8	on	on	ADP
admet-442	50	9	cancer	cancer	NOUN
admet-442	50	10	was	be	AUX
admet-442	50	11	also	also	ADV
admet-442	50	12	shown	show	VERB
admet-442	50	13	by	by	ADP
admet-442	50	14	suppression	suppression	NOUN
admet-442	50	15	of	of	ADP
admet-442	50	16	anti	anti	ADJ
admet-442	50	17	-	-	ADJ
admet-442	50	18	pd	pd	ADJ
admet-442	50	19	-	-	PUNCT
admet-442	50	20	l1	l1	PROPN
admet-442	50	21	antibody	antibody	NOUN
admet-442	50	22	on	on	ADP
admet-442	50	23	the	the	DET
admet-442	50	24	growth	growth	NOUN
admet-442	50	25	of	of	ADP
admet-442	50	26	myeloma	myeloma	NOUN
admet-442	50	27	cells	cell	NOUN
admet-442	50	28	[	[	X
admet-442	50	29	37	37	NUM
admet-442	50	30	]	]	SYM
admet-442	50	31	.	.	PUNCT
admet-442	51	1	pd	pd	PROPN
admet-442	51	2	-	-	PROPN
admet-442	51	3	l1expression	l1expression	NOUN
admet-442	51	4	in	in	ADP
admet-442	51	5	immune	immune	ADJ
admet-442	51	6	diseases	disease	NOUN
admet-442	51	7	as	as	ADP
admet-442	51	8	a	a	DET
admet-442	51	9	target	target	NOUN
admet-442	51	10	of	of	ADP
admet-442	51	11	immune	immune	ADJ
admet-442	51	12	checkpoint	checkpoint	NOUN
admet-442	51	13	inhibitor	inhibitor	NOUN
admet-442	51	14	,	,	PUNCT
admet-442	51	15	pd	pd	PROPN
admet-442	51	16	-	-	PROPN
admet-442	51	17	l1	l1	PROPN
admet-442	51	18	is	be	AUX
admet-442	51	19	not	not	PART
admet-442	51	20	only	only	ADV
admet-442	51	21	associated	associate	VERB
admet-442	51	22	with	with	ADP
admet-442	51	23	anti	anti	ADJ
admet-442	51	24	-	-	ADJ
admet-442	51	25	cancer	cancer	ADJ
admet-442	51	26	treatment	treatment	NOUN
admet-442	51	27	,	,	PUNCT
admet-442	51	28	but	but	CCONJ
admet-442	51	29	also	also	ADV
admet-442	51	30	with	with	ADP
admet-442	51	31	other	other	ADJ
admet-442	51	32	immune	immune	ADJ
admet-442	51	33	diseases	disease	NOUN
admet-442	51	34	.	.	PUNCT
admet-442	52	1	pd	pd	PROPN
admet-442	52	2	-	-	PROPN
admet-442	52	3	l1	l1	PROPN
admet-442	52	4	has	have	VERB
admet-442	52	5	a	a	DET
admet-442	52	6	strong	strong	ADJ
admet-442	52	7	link	link	NOUN
admet-442	52	8	with	with	ADP
admet-442	52	9	autoimmune	autoimmune	ADJ
admet-442	52	10	disease	disease	NOUN
admet-442	52	11	.	.	PUNCT
admet-442	53	1	in	in	ADP
admet-442	53	2	non	non	ADJ
admet-442	53	3	-	-	ADJ
admet-442	53	4	obese	obese	ADJ
admet-442	53	5	diabetic	diabetic	ADJ
admet-442	53	6	(	(	PUNCT
admet-442	53	7	nod	nod	NOUN
admet-442	53	8	)	)	PUNCT
admet-442	53	9	prediabetic	prediabetic	ADJ
admet-442	53	10	murine	murine	ADJ
admet-442	53	11	model	model	NOUN
admet-442	53	12	,	,	PUNCT
admet-442	53	13	pd	pd	PROPN
admet-442	53	14	-	-	PUNCT
admet-442	53	15	l1	l1	PROPN
admet-442	53	16	expression	expression	NOUN
admet-442	53	17	was	be	AUX
admet-442	53	18	significantly	significantly	ADV
admet-442	53	19	upregulated	upregulate	VERB
admet-442	53	20	on	on	ADP
admet-442	53	21	infiltrating	infiltrate	VERB
admet-442	53	22	mononuclear	mononuclear	ADJ
admet-442	53	23	cells	cell	NOUN
admet-442	53	24	in	in	ADP
admet-442	53	25	the	the	DET
admet-442	53	26	islet	islet	NOUN
admet-442	54	1	[	[	X
admet-442	54	2	38	38	NUM
admet-442	54	3	]	]	PUNCT
admet-442	54	4	.	.	PUNCT
admet-442	55	1	mohammed	mohammed	PROPN
admet-442	55	2	et	et	PROPN
admet-442	55	3	al	al	PROPN
admet-442	55	4	.	.	PROPN
admet-442	55	5	also	also	ADV
admet-442	55	6	reported	report	VERB
admet-442	55	7	that	that	SCONJ
admet-442	55	8	expression	expression	NOUN
admet-442	55	9	of	of	ADP
admet-442	55	10	pd	pd	PROPN
admet-442	55	11	-	-	PROPN
admet-442	55	12	l1	l1	PROPN
admet-442	55	13	was	be	AUX
admet-442	55	14	found	find	VERB
admet-442	55	15	in	in	ADP
admet-442	55	16	the	the	DET
admet-442	55	17	inflamed	inflame	VERB
admet-442	55	18	islets	islet	NOUN
admet-442	55	19	of	of	ADP
admet-442	55	20	nod	nod	NOUN
admet-442	55	21	mice	mouse	NOUN
admet-442	55	22	,	,	PUNCT
admet-442	55	23	suggesting	suggest	VERB
admet-442	55	24	a	a	DET
admet-442	55	25	regulatory	regulatory	ADJ
admet-442	55	26	role	role	NOUN
admet-442	55	27	of	of	ADP
admet-442	55	28	pd	pd	PROPN
admet-442	55	29	-	-	PROPN
admet-442	55	30	l1	l1	PROPN
admet-442	55	31	on	on	ADP
admet-442	55	32	the	the	DET
admet-442	55	33	progression	progression	NOUN
admet-442	55	34	of	of	ADP
admet-442	55	35	autoimmune	autoimmune	ADJ
admet-442	55	36	admet	admet	PROPN
admet-442	55	37	&	&	CCONJ
admet-442	55	38	dmpk	dmpk	PROPN
admet-442	55	39	5(3	5(3	NUM
admet-442	55	40	)	)	PUNCT
admet-442	55	41	(	(	PUNCT
admet-442	55	42	2017	2017	NUM
admet-442	55	43	)	)	PUNCT
admet-442	55	44	159	159	NUM
admet-442	55	45	-	-	SYM
admet-442	55	46	172	172	NUM
admet-442	55	47	the	the	DET
admet-442	55	48	function	function	NOUN
admet-442	55	49	and	and	CCONJ
admet-442	55	50	regulation	regulation	NOUN
admet-442	55	51	of	of	ADP
admet-442	55	52	pd	pd	PROPN
admet-442	55	53	-	-	PROPN
admet-442	55	54	l1	l1	PROPN
admet-442	55	55	in	in	ADP
admet-442	55	56	immunotherapy	immunotherapy	NOUN
admet-442	55	57	doi	doi	NOUN
admet-442	55	58	:	:	PUNCT
admet-442	55	59	10.5599	10.5599	NUM
admet-442	55	60	/	/	SYM
admet-442	55	61	admet.5.3.442	admet.5.3.442	NUM
admet-442	55	62	161	161	NUM
admet-442	55	63	diabetes	diabetes	NOUN
admet-442	55	64	[	[	X
admet-442	55	65	39	39	NUM
admet-442	55	66	]	]	PUNCT
admet-442	55	67	.	.	PUNCT
admet-442	56	1	pd	pd	PROPN
admet-442	56	2	-	-	PROPN
admet-442	56	3	l1	l1	PROPN
admet-442	56	4	has	have	AUX
admet-442	56	5	been	be	AUX
admet-442	56	6	reported	report	VERB
admet-442	56	7	to	to	PART
admet-442	56	8	contribute	contribute	VERB
admet-442	56	9	to	to	ADP
admet-442	56	10	etiopathogenetic	etiopathogenetic	ADJ
admet-442	56	11	of	of	ADP
admet-442	56	12	autoimmune	autoimmune	ADJ
admet-442	56	13	diseases	disease	NOUN
admet-442	56	14	in	in	ADP
admet-442	56	15	mouse	mouse	NOUN
admet-442	56	16	models	model	NOUN
admet-442	56	17	.	.	PUNCT
admet-442	57	1	mohammed	mohammed	PROPN
admet-442	57	2	et	et	PROPN
admet-442	57	3	al	al	PROPN
admet-442	57	4	.	.	PROPN
admet-442	57	5	reported	report	VERB
admet-442	57	6	that	that	DET
admet-442	57	7	blockade	blockade	NOUN
admet-442	57	8	of	of	ADP
admet-442	57	9	pd	pd	PROPN
admet-442	57	10	-	-	PROPN
admet-442	57	11	l1	l1	PROPN
admet-442	57	12	by	by	ADP
admet-442	57	13	monoclonal	monoclonal	NOUN
admet-442	57	14	antibodies	antibody	NOUN
admet-442	57	15	(	(	PUNCT
admet-442	57	16	mabs	mab	NOUN
admet-442	57	17	)	)	PUNCT
admet-442	57	18	against	against	ADP
admet-442	57	19	pd	pd	PROPN
admet-442	57	20	-	-	PROPN
admet-442	57	21	l1	l1	PROPN
admet-442	57	22	led	lead	VERB
admet-442	57	23	to	to	ADP
admet-442	57	24	diabetes	diabetes	NOUN
admet-442	57	25	in	in	ADP
admet-442	57	26	female	female	ADJ
admet-442	57	27	nod	nod	NOUN
admet-442	57	28	mice	mouse	NOUN
admet-442	58	1	[	[	X
admet-442	58	2	39	39	NUM
admet-442	58	3	]	]	PUNCT
admet-442	58	4	.	.	PUNCT
admet-442	59	1	the	the	DET
admet-442	59	2	nod	nod	PROPN
admet-442	59	3	mouse	mouse	NOUN
admet-442	59	4	model	model	NOUN
admet-442	59	5	is	be	AUX
admet-442	59	6	useful	useful	ADJ
admet-442	59	7	for	for	ADP
admet-442	59	8	studying	study	VERB
admet-442	59	9	diabetes	diabetes	NOUN
admet-442	59	10	caused	cause	VERB
admet-442	59	11	by	by	ADP
admet-442	59	12	autoimmune	autoimmune	ADJ
admet-442	59	13	process	process	NOUN
admet-442	59	14	[	[	X
admet-442	59	15	40	40	NUM
admet-442	59	16	]	]	PUNCT
admet-442	59	17	.	.	PUNCT
admet-442	60	1	blockade	blockade	NOUN
admet-442	60	2	of	of	ADP
admet-442	60	3	pd-1	pd-1	ADP
admet-442	60	4	/	/	SYM
admet-442	60	5	pd	pd	ADJ
admet-442	60	6	-	-	PUNCT
admet-442	60	7	l1	l1	PROPN
admet-442	60	8	interaction	interaction	NOUN
admet-442	60	9	did	do	AUX
admet-442	60	10	n’t	not	PART
admet-442	60	11	induce	induce	VERB
admet-442	60	12	diabetes	diabetes	NOUN
admet-442	60	13	in	in	ADP
admet-442	60	14	nor	nor	CCONJ
admet-442	60	15	mice	mouse	NOUN
admet-442	60	16	,	,	PUNCT
admet-442	60	17	showing	show	VERB
admet-442	60	18	the	the	DET
admet-442	60	19	specific	specific	ADJ
admet-442	60	20	islet	islet	NOUN
admet-442	60	21	cell	cell	NOUN
admet-442	60	22	toxicity	toxicity	NOUN
admet-442	60	23	by	by	ADP
admet-442	60	24	mabs	mab	NOUN
admet-442	60	25	treatment	treatment	NOUN
admet-442	60	26	[	[	X
admet-442	60	27	39	39	NUM
admet-442	60	28	]	]	PUNCT
admet-442	60	29	.	.	PUNCT
admet-442	61	1	bing	bing	VERB
admet-442	61	2	et	et	PROPN
admet-442	61	3	al	al	PROPN
admet-442	61	4	.	.	PROPN
admet-442	61	5	reported	report	VERB
admet-442	61	6	that	that	SCONJ
admet-442	61	7	in	in	ADP
admet-442	61	8	balb	balb	ADJ
admet-442	61	9	/	/	SYM
admet-442	61	10	c	c	NOUN
admet-442	61	11	mice	mouse	NOUN
admet-442	61	12	,	,	PUNCT
admet-442	61	13	blockade	blockade	NOUN
admet-442	61	14	of	of	ADP
admet-442	61	15	pd	pd	PROPN
admet-442	61	16	-	-	PROPN
admet-442	61	17	l1	l1	PROPN
admet-442	61	18	remarkably	remarkably	ADV
admet-442	61	19	increased	increase	VERB
admet-442	61	20	incidence	incidence	NOUN
admet-442	61	21	of	of	ADP
admet-442	61	22	experimental	experimental	ADJ
admet-442	61	23	autoimmune	autoimmune	ADJ
admet-442	61	24	encephalomyelitis	encephalomyelitis	NOUN
admet-442	61	25	(	(	PUNCT
admet-442	61	26	eae	eae	PROPN
admet-442	61	27	)	)	PUNCT
admet-442	61	28	in	in	ADP
admet-442	61	29	the	the	DET
admet-442	61	30	presence	presence	NOUN
admet-442	61	31	of	of	ADP
admet-442	61	32	myelin	myelin	ADJ
admet-442	61	33	oligodendrocyte	oligodendrocyte	ADJ
admet-442	61	34	glycoprotein	glycoprotein	NOUN
admet-442	61	35	(	(	PUNCT
admet-442	61	36	mog	mog	NOUN
admet-442	61	37	)	)	PUNCT
admet-442	61	38	peptide	peptide	VERB
admet-442	61	39	35–55	35–55	NUM
admet-442	62	1	[	[	X
admet-442	62	2	41	41	NUM
admet-442	62	3	]	]	PUNCT
admet-442	62	4	.	.	PUNCT
admet-442	63	1	furthermore	furthermore	ADV
admet-442	63	2	,	,	PUNCT
admet-442	63	3	in	in	ADP
admet-442	63	4	myelin	myelin	NOUN
admet-442	63	5	proteolipid	proteolipid	NOUN
admet-442	63	6	protein	protein	NOUN
admet-442	63	7	(	(	PUNCT
admet-442	63	8	plp	plp	PROPN
admet-442	63	9	)	)	PUNCT
admet-442	63	10	peptide	peptide	NOUN
admet-442	63	11	139–151	139–151	NUM
admet-442	63	12	immunized	immunize	VERB
admet-442	63	13	b10.s	b10.	NOUN
admet-442	63	14	mice	mouse	NOUN
admet-442	63	15	,	,	PUNCT
admet-442	63	16	blockade	blockade	NOUN
admet-442	63	17	of	of	ADP
admet-442	63	18	pd	pd	PROPN
admet-442	63	19	-	-	PROPN
admet-442	63	20	l1	l1	PROPN
admet-442	63	21	also	also	ADV
admet-442	63	22	significantly	significantly	ADV
admet-442	63	23	enhanced	enhance	VERB
admet-442	63	24	severity	severity	NOUN
admet-442	63	25	of	of	ADP
admet-442	63	26	eae	eae	PROPN
admet-442	63	27	[	[	X
admet-442	63	28	41	41	NUM
admet-442	63	29	]	]	PUNCT
admet-442	63	30	.	.	PUNCT
admet-442	64	1	pd	pd	PROPN
admet-442	64	2	-	-	PUNCT
admet-442	64	3	l1	l1	PROPN
admet-442	64	4	deficiency	deficiency	NOUN
admet-442	64	5	mice	mouse	NOUN
admet-442	64	6	were	be	AUX
admet-442	64	7	completely	completely	ADV
admet-442	64	8	susceptible	susceptible	ADJ
admet-442	64	9	to	to	ADP
admet-442	64	10	eae	eae	PROPN
admet-442	64	11	after	after	ADP
admet-442	64	12	e2	e2	PROPN
admet-442	64	13	(	(	PUNCT
admet-442	64	14	known	know	VERB
admet-442	64	15	as	as	ADP
admet-442	64	16	17β	17β	NOUN
admet-442	64	17	-	-	PUNCT
admet-442	64	18	estradiol	estradiol	PROPN
admet-442	64	19	,	,	PUNCT
admet-442	64	20	an	an	DET
admet-442	64	21	estrogen	estrogen	NOUN
admet-442	64	22	)	)	PUNCT
admet-442	64	23	treatment	treatment	NOUN
admet-442	64	24	[	[	X
admet-442	64	25	42	42	NUM
admet-442	64	26	]	]	PUNCT
admet-442	64	27	.	.	PUNCT
admet-442	65	1	this	this	DET
admet-442	65	2	study	study	NOUN
admet-442	65	3	also	also	ADV
admet-442	65	4	reported	report	VERB
admet-442	65	5	that	that	SCONJ
admet-442	65	6	the	the	DET
admet-442	65	7	protective	protective	ADJ
admet-442	65	8	effect	effect	NOUN
admet-442	65	9	against	against	ADP
admet-442	65	10	eae	eae	PROPN
admet-442	65	11	mediated	mediate	VERB
admet-442	65	12	by	by	ADP
admet-442	65	13	e2	e2	PROPN
admet-442	65	14	was	be	AUX
admet-442	65	15	significantly	significantly	ADV
admet-442	65	16	reduced	reduce	VERB
admet-442	65	17	in	in	ADP
admet-442	65	18	recipient	recipient	NOUN
admet-442	65	19	mice	mouse	NOUN
admet-442	65	20	transfected	transfecte	VERB
admet-442	65	21	with	with	ADP
admet-442	65	22	pd	pd	PROPN
admet-442	65	23	-	-	ADJ
admet-442	65	24	l1−/−	l1−/−	ADJ
admet-442	65	25	b	b	NOUN
admet-442	65	26	-	-	PUNCT
admet-442	65	27	cell	cell	NOUN
admet-442	66	1	[	[	X
admet-442	66	2	42	42	NUM
admet-442	66	3	]	]	PUNCT
admet-442	66	4	.	.	PUNCT
admet-442	67	1	therefore	therefore	ADV
admet-442	67	2	pd	pd	PROPN
admet-442	67	3	-	-	PROPN
admet-442	67	4	l1	l1	PROPN
admet-442	67	5	in	in	ADP
admet-442	67	6	b	b	PROPN
admet-442	67	7	cells	cell	NOUN
admet-442	67	8	may	may	AUX
admet-442	67	9	be	be	AUX
admet-442	67	10	crucial	crucial	ADJ
admet-442	67	11	for	for	ADP
admet-442	67	12	the	the	DET
admet-442	67	13	protective	protective	ADJ
admet-442	67	14	effect	effect	NOUN
admet-442	67	15	of	of	ADP
admet-442	67	16	estrogen	estrogen	NOUN
admet-442	67	17	against	against	ADP
admet-442	67	18	eae	eae	PROPN
admet-442	67	19	.	.	PUNCT
admet-442	68	1	enhanced	enhance	VERB
admet-442	68	2	expression	expression	NOUN
admet-442	68	3	of	of	ADP
admet-442	68	4	pd	pd	PROPN
admet-442	68	5	-	-	PROPN
admet-442	68	6	l1	l1	PROPN
admet-442	68	7	was	be	AUX
admet-442	68	8	present	present	ADJ
admet-442	68	9	on	on	ADP
admet-442	68	10	ductal	ductal	ADJ
admet-442	68	11	and	and	CCONJ
admet-442	68	12	acinar	acinar	ADJ
admet-442	68	13	epithelial	epithelial	ADJ
admet-442	68	14	cells	cell	NOUN
admet-442	68	15	in	in	ADP
admet-442	68	16	the	the	DET
admet-442	68	17	salivary	salivary	ADJ
admet-442	68	18	glands	gland	NOUN
admet-442	68	19	of	of	ADP
admet-442	68	20	patients	patient	NOUN
admet-442	68	21	with	with	ADP
admet-442	68	22	sjogren	sjogren	PROPN
admet-442	68	23	’s	’s	PART
admet-442	68	24	syndrome	syndrome	NOUN
admet-442	69	1	[	[	X
admet-442	69	2	43	43	NUM
admet-442	69	3	]	]	PUNCT
admet-442	69	4	.	.	PUNCT
admet-442	70	1	increased	increase	VERB
admet-442	70	2	expression	expression	NOUN
admet-442	70	3	of	of	ADP
admet-442	70	4	pd	pd	PROPN
admet-442	70	5	-	-	PROPN
admet-442	70	6	l1	l1	PROPN
admet-442	70	7	has	have	AUX
admet-442	70	8	also	also	ADV
admet-442	70	9	been	be	AUX
admet-442	70	10	found	find	VERB
admet-442	70	11	on	on	ADP
admet-442	70	12	t	t	NOUN
admet-442	70	13	cells	cell	NOUN
admet-442	70	14	,	,	PUNCT
admet-442	70	15	b	b	NOUN
admet-442	70	16	cells	cell	NOUN
admet-442	70	17	as	as	ADV
admet-442	70	18	well	well	ADV
admet-442	70	19	as	as	ADP
admet-442	70	20	monocytes	monocyte	NOUN
admet-442	70	21	of	of	ADP
admet-442	70	22	patients	patient	NOUN
admet-442	70	23	with	with	ADP
admet-442	70	24	systemic	systemic	ADJ
admet-442	70	25	lupus	lupus	NOUN
admet-442	70	26	erythematosus	erythematosus	NOUN
admet-442	70	27	(	(	PUNCT
admet-442	70	28	sle	sle	PROPN
admet-442	70	29	)	)	PUNCT
admet-442	70	30	,	,	PUNCT
admet-442	70	31	implying	imply	VERB
admet-442	70	32	that	that	SCONJ
admet-442	70	33	pd	pd	PROPN
admet-442	70	34	-	-	PROPN
admet-442	70	35	l1	l1	PROPN
admet-442	70	36	might	might	AUX
admet-442	70	37	be	be	AUX
admet-442	70	38	correlated	correlate	VERB
admet-442	70	39	with	with	ADP
admet-442	70	40	sle	sle	PROPN
admet-442	70	41	disease	disease	NOUN
admet-442	71	1	[	[	X
admet-442	71	2	44	44	NUM
admet-442	71	3	]	]	PUNCT
admet-442	71	4	.	.	PUNCT
admet-442	72	1	the	the	DET
admet-442	72	2	expression	expression	NOUN
admet-442	72	3	of	of	ADP
admet-442	72	4	pd	pd	PROPN
admet-442	72	5	-	-	PROPN
admet-442	72	6	l1	l1	PROPN
admet-442	72	7	increased	increase	VERB
admet-442	72	8	on	on	ADP
admet-442	72	9	mononuclear	mononuclear	ADJ
admet-442	72	10	cells	cell	NOUN
admet-442	72	11	in	in	ADP
admet-442	72	12	the	the	DET
admet-442	72	13	lamina	lamina	ADJ
admet-442	72	14	propria	propria	NOUN
admet-442	72	15	of	of	ADP
admet-442	72	16	inflammatory	inflammatory	ADJ
admet-442	72	17	bowel	bowel	NOUN
admet-442	72	18	disease	disease	NOUN
admet-442	72	19	(	(	PUNCT
admet-442	72	20	ibd	ibd	NOUN
admet-442	72	21	)	)	PUNCT
admet-442	72	22	patients	patient	NOUN
admet-442	72	23	,	,	PUNCT
admet-442	72	24	as	as	ADV
admet-442	72	25	well	well	ADV
admet-442	72	26	as	as	ADP
admet-442	72	27	on	on	ADP
admet-442	72	28	mononuclear	mononuclear	ADJ
admet-442	72	29	cells	cell	NOUN
admet-442	72	30	in	in	ADP
admet-442	72	31	the	the	DET
admet-442	72	32	lamina	lamina	ADJ
admet-442	72	33	propria	propria	PROPN
admet-442	72	34	in	in	ADP
admet-442	72	35	experimental	experimental	ADJ
admet-442	72	36	colitic	colitic	ADJ
admet-442	72	37	mice	mouse	NOUN
admet-442	72	38	[	[	X
admet-442	72	39	45	45	NUM
admet-442	72	40	]	]	PUNCT
admet-442	72	41	.	.	PUNCT
admet-442	73	1	pd	pd	PROPN
admet-442	73	2	-	-	PROPN
admet-442	73	3	l1	l1	PROPN
admet-442	73	4	in	in	ADP
admet-442	73	5	virus	virus	NOUN
admet-442	73	6	associated	associate	VERB
admet-442	73	7	disease	disease	NOUN
admet-442	73	8	besides	besides	SCONJ
admet-442	73	9	,	,	PUNCT
admet-442	73	10	pd	pd	PROPN
admet-442	73	11	-	-	PROPN
admet-442	73	12	l1	l1	PROPN
admet-442	73	13	is	be	AUX
admet-442	73	14	also	also	ADV
admet-442	73	15	associated	associate	VERB
admet-442	73	16	with	with	ADP
admet-442	73	17	chronic	chronic	ADJ
admet-442	73	18	viral	viral	ADJ
admet-442	73	19	infection	infection	NOUN
admet-442	73	20	and	and	CCONJ
admet-442	73	21	chronic	chronic	ADJ
admet-442	73	22	inflammatory	inflammatory	ADJ
admet-442	73	23	diseases	disease	NOUN
admet-442	73	24	.	.	PUNCT
admet-442	74	1	upregulated	upregulate	VERB
admet-442	74	2	expression	expression	NOUN
admet-442	74	3	of	of	ADP
admet-442	74	4	pd	pd	PROPN
admet-442	74	5	-	-	PROPN
admet-442	74	6	l1	l1	PROPN
admet-442	74	7	was	be	AUX
admet-442	74	8	found	find	VERB
admet-442	74	9	in	in	ADP
admet-442	74	10	livers	liver	NOUN
admet-442	74	11	of	of	ADP
admet-442	74	12	patients	patient	NOUN
admet-442	74	13	infected	infect	VERB
admet-442	74	14	with	with	ADP
admet-442	74	15	hbv	hbv	NOUN
admet-442	74	16	compared	compare	VERB
admet-442	74	17	with	with	ADP
admet-442	74	18	healthy	healthy	ADJ
admet-442	74	19	donors	donor	NOUN
admet-442	74	20	[	[	X
admet-442	74	21	46	46	NUM
admet-442	74	22	]	]	PUNCT
admet-442	74	23	.	.	PUNCT
admet-442	75	1	previous	previous	ADJ
admet-442	75	2	studies	study	NOUN
admet-442	75	3	showed	show	VERB
admet-442	75	4	that	that	SCONJ
admet-442	75	5	most	most	ADJ
admet-442	75	6	of	of	ADP
admet-442	75	7	merkel	merkel	NOUN
admet-442	75	8	cell	cell	NOUN
admet-442	75	9	carcinoma	carcinoma	NOUN
admet-442	75	10	(	(	PUNCT
admet-442	75	11	mcc	mcc	NOUN
admet-442	75	12	)	)	PUNCT
admet-442	75	13	were	be	AUX
admet-442	75	14	linked	link	VERB
admet-442	75	15	to	to	ADP
admet-442	75	16	merkel	merkel	PROPN
admet-442	75	17	cell	cell	NOUN
admet-442	75	18	polyomavirus	polyomavirus	NOUN
admet-442	75	19	(	(	PUNCT
admet-442	75	20	mcpyv	mcpyv	NOUN
admet-442	75	21	)	)	PUNCT
admet-442	75	22	infection	infection	NOUN
admet-442	76	1	[	[	X
admet-442	76	2	47	47	NUM
admet-442	76	3	]	]	PUNCT
admet-442	76	4	.	.	PUNCT
admet-442	76	5	enhanced	enhance	VERB
admet-442	76	6	expression	expression	NOUN
admet-442	76	7	of	of	ADP
admet-442	76	8	pd	pd	PROPN
admet-442	76	9	-	-	PROPN
admet-442	76	10	l1	l1	PROPN
admet-442	76	11	was	be	AUX
admet-442	76	12	found	find	VERB
admet-442	76	13	in	in	ADP
admet-442	76	14	mcpyv	mcpyv	NOUN
admet-442	76	15	infected	infect	VERB
admet-442	76	16	mcc	mcc	NOUN
admet-442	76	17	cells	cell	NOUN
admet-442	76	18	compared	compare	VERB
admet-442	76	19	to	to	ADP
admet-442	76	20	mcpyv	mcpyv	ADV
admet-442	76	21	-	-	PUNCT
admet-442	76	22	negative	negative	ADJ
admet-442	76	23	mcc	mcc	NOUN
admet-442	76	24	cells	cell	NOUN
admet-442	76	25	[	[	X
admet-442	76	26	48	48	NUM
admet-442	76	27	]	]	PUNCT
admet-442	76	28	.	.	PUNCT
admet-442	77	1	it	it	PRON
admet-442	77	2	was	be	AUX
admet-442	77	3	reported	report	VERB
admet-442	77	4	that	that	SCONJ
admet-442	77	5	interferon	interferon	NOUN
admet-442	77	6	(	(	PUNCT
admet-442	77	7	ifn)-γ	ifn)-γ	NOUN
admet-442	77	8	had	have	VERB
admet-442	77	9	an	an	DET
admet-442	77	10	effect	effect	NOUN
admet-442	77	11	on	on	ADP
admet-442	77	12	increasing	increase	VERB
admet-442	77	13	the	the	DET
admet-442	77	14	number	number	NOUN
admet-442	77	15	of	of	ADP
admet-442	77	16	cd8	cd8	PROPN
admet-442	77	17	+	+	PROPN
admet-442	77	18	cytotoxic	cytotoxic	ADJ
admet-442	77	19	t	t	NOUN
admet-442	77	20	lymphocytes	lymphocyte	VERB
admet-442	77	21	(	(	PUNCT
admet-442	77	22	ctls	ctls	PROPN
admet-442	77	23	)	)	PUNCT
admet-442	77	24	when	when	SCONJ
admet-442	77	25	infected	infect	VERB
admet-442	77	26	by	by	ADP
admet-442	77	27	the	the	DET
admet-442	77	28	virus	virus	NOUN
admet-442	78	1	[	[	X
admet-442	78	2	49	49	NUM
admet-442	78	3	]	]	PUNCT
admet-442	78	4	.	.	PUNCT
admet-442	79	1	blockade	blockade	NOUN
admet-442	79	2	of	of	ADP
admet-442	79	3	pd	pd	PROPN
admet-442	79	4	-	-	PROPN
admet-442	79	5	l1	l1	PROPN
admet-442	79	6	enhanced	enhance	VERB
admet-442	79	7	the	the	DET
admet-442	79	8	ability	ability	NOUN
admet-442	79	9	of	of	ADP
admet-442	79	10	cd8	cd8	PROPN
admet-442	79	11	+	+	PROPN
admet-442	79	12	ctls	ctls	PROPN
admet-442	79	13	to	to	PART
admet-442	79	14	produce	produce	VERB
admet-442	79	15	ifn	ifn	PROPN
admet-442	79	16	-	-	PUNCT
admet-442	79	17	γ	γ	NOUN
admet-442	79	18	through	through	ADP
admet-442	79	19	an	an	DET
admet-442	79	20	increase	increase	NOUN
admet-442	79	21	in	in	ADP
admet-442	79	22	the	the	DET
admet-442	79	23	number	number	NOUN
admet-442	79	24	of	of	ADP
admet-442	79	25	ifn	ifn	NOUN
admet-442	79	26	-	-	PUNCT
admet-442	79	27	γproducing	γproducing	ADJ
admet-442	79	28	hbv	hbv	NOUN
admet-442	79	29	-	-	PUNCT
admet-442	79	30	specific	specific	ADJ
admet-442	79	31	ctls	ctls	NOUN
admet-442	79	32	[	[	X
admet-442	79	33	50	50	NUM
admet-442	79	34	]	]	PUNCT
admet-442	79	35	.	.	PUNCT
admet-442	80	1	daniel	daniel	PROPN
admet-442	80	2	et	et	PROPN
admet-442	80	3	al	al	PROPN
admet-442	80	4	.	.	PROPN
admet-442	80	5	reported	report	VERB
admet-442	80	6	that	that	SCONJ
admet-442	80	7	in	in	ADP
admet-442	80	8	lymphocytic	lymphocytic	ADJ
admet-442	80	9	choriomeningitis	choriomeningitis	NOUN
admet-442	80	10	virus	virus	NOUN
admet-442	80	11	(	(	PUNCT
admet-442	80	12	lcmv	lcmv	PROPN
admet-442	80	13	)	)	PUNCT
admet-442	80	14	infected	infect	VERB
admet-442	80	15	mice	mouse	NOUN
admet-442	80	16	blockade	blockade	NOUN
admet-442	80	17	of	of	ADP
admet-442	80	18	pd	pd	PROPN
admet-442	80	19	-	-	PROPN
admet-442	80	20	l1	l1	PROPN
admet-442	80	21	and	and	CCONJ
admet-442	80	22	pd-1	pd-1	ADV
admet-442	80	23	interaction	interaction	NOUN
admet-442	80	24	restored	restore	VERB
admet-442	80	25	the	the	DET
admet-442	80	26	ability	ability	NOUN
admet-442	80	27	of	of	ADP
admet-442	80	28	exhausted	exhausted	ADJ
admet-442	80	29	cd8	cd8	PROPN
admet-442	80	30	t	t	PROPN
admet-442	80	31	cell	cell	NOUN
admet-442	80	32	to	to	PART
admet-442	80	33	kill	kill	VERB
admet-442	80	34	infected	infected	ADJ
admet-442	80	35	cells	cell	NOUN
admet-442	80	36	[	[	X
admet-442	80	37	51	51	NUM
admet-442	80	38	]	]	PUNCT
admet-442	80	39	.	.	PUNCT
admet-442	81	1	the	the	DET
admet-442	81	2	pd	pd	PROPN
admet-442	81	3	-	-	PUNCT
admet-442	81	4	l1	l1	PROPN
admet-442	81	5	/	/	SYM
admet-442	81	6	pd-1	pd-1	NOUN
admet-442	81	7	pathway	pathway	NOUN
admet-442	81	8	has	have	AUX
admet-442	81	9	also	also	ADV
admet-442	81	10	been	be	AUX
admet-442	81	11	found	find	VERB
admet-442	81	12	to	to	PART
admet-442	81	13	mediate	mediate	VERB
admet-442	81	14	the	the	DET
admet-442	81	15	function	function	NOUN
admet-442	81	16	of	of	ADP
admet-442	81	17	virus	virus	NOUN
admet-442	81	18	-	-	PUNCT
admet-442	81	19	specific	specific	ADJ
admet-442	81	20	exhausted	exhausted	ADJ
admet-442	81	21	cd8	cd8	PROPN
admet-442	81	22	+	+	PROPN
admet-442	81	23	t	t	NOUN
admet-442	81	24	cell	cell	NOUN
admet-442	81	25	in	in	ADP
admet-442	81	26	human	human	ADJ
admet-442	81	27	immunodeficiency	immunodeficiency	NOUN
admet-442	81	28	virus	virus	NOUN
admet-442	81	29	(	(	PUNCT
admet-442	81	30	hiv	hiv	PROPN
admet-442	81	31	)	)	PUNCT
admet-442	81	32	infected	infected	ADJ
admet-442	81	33	patients	patient	NOUN
admet-442	81	34	in	in	ADP
admet-442	81	35	several	several	ADJ
admet-442	81	36	studies	study	NOUN
admet-442	81	37	[	[	X
admet-442	81	38	51	51	NUM
admet-442	81	39	]	]	PUNCT
admet-442	81	40	.	.	PUNCT
admet-442	82	1	dai	dai	PROPN
admet-442	82	2	et	et	PROPN
admet-442	82	3	al	al	PROPN
admet-442	82	4	.	.	PROPN
admet-442	82	5	showed	show	VERB
admet-442	82	6	that	that	DET
admet-442	82	7	blockade	blockade	NOUN
admet-442	82	8	of	of	ADP
admet-442	82	9	interaction	interaction	NOUN
admet-442	82	10	of	of	ADP
admet-442	82	11	pd-1	pd-1	ADP
admet-442	82	12	/	/	SYM
admet-442	82	13	pd	pd	NOUN
admet-442	82	14	-	-	PROPN
admet-442	82	15	l1	l1	PROPN
admet-442	82	16	by	by	ADP
admet-442	82	17	anti	anti	ADJ
admet-442	82	18	-	-	ADJ
admet-442	82	19	pd	pd	ADJ
admet-442	82	20	-	-	PUNCT
admet-442	82	21	l1	l1	NOUN
admet-442	82	22	restored	restore	VERB
admet-442	82	23	immune	immune	ADJ
admet-442	82	24	response	response	NOUN
admet-442	82	25	generated	generate	VERB
admet-442	82	26	by	by	ADP
admet-442	82	27	cd8	cd8	PROPN
admet-442	82	28	+	+	PROPN
admet-442	82	29	t	t	NOUN
admet-442	82	30	cell	cell	NOUN
admet-442	82	31	after	after	ADP
admet-442	82	32	being	be	AUX
admet-442	82	33	infected	infect	VERB
admet-442	82	34	by	by	ADP
admet-442	82	35	hiv	hiv	PROPN
admet-442	83	1	[	[	X
admet-442	83	2	52	52	NUM
admet-442	83	3	]	]	PUNCT
admet-442	83	4	.	.	PUNCT
admet-442	84	1	anti	anti	ADJ
admet-442	84	2	-	-	ADJ
admet-442	84	3	pd	pd	ADJ
admet-442	84	4	-	-	PUNCT
admet-442	84	5	l1	l1	PROPN
admet-442	84	6	antibody	antibody	NOUN
admet-442	84	7	also	also	ADV
admet-442	84	8	enhanced	enhance	VERB
admet-442	84	9	proliferation	proliferation	NOUN
admet-442	84	10	and	and	CCONJ
admet-442	84	11	cytokine	cytokine	ADJ
admet-442	84	12	production	production	NOUN
admet-442	84	13	of	of	ADP
admet-442	84	14	hepatitis	hepatitis	PROPN
admet-442	84	15	c	c	PROPN
admet-442	84	16	virus	virus	NOUN
admet-442	84	17	(	(	PUNCT
admet-442	84	18	hcv)-specific	hcv)-specific	PROPN
admet-442	84	19	cd8	cd8	PROPN
admet-442	84	20	cells	cell	NOUN
admet-442	84	21	during	during	ADP
admet-442	84	22	chronic	chronic	ADJ
admet-442	84	23	hcv	hcv	NOUN
admet-442	84	24	infection	infection	NOUN
admet-442	84	25	in	in	ADP
admet-442	84	26	the	the	DET
admet-442	84	27	study	study	NOUN
admet-442	84	28	reported	report	VERB
admet-442	84	29	by	by	ADP
admet-442	84	30	simona	simona	PROPN
admet-442	84	31	et	et	PROPN
admet-442	84	32	al	al	PROPN
admet-442	84	33	.	.	PUNCT
admet-442	85	1	[	[	X
admet-442	85	2	53	53	NUM
admet-442	85	3	]	]	PUNCT
admet-442	85	4	.	.	PUNCT
admet-442	86	1	the	the	DET
admet-442	86	2	result	result	NOUN
admet-442	86	3	of	of	ADP
admet-442	86	4	these	these	DET
admet-442	86	5	studies	study	NOUN
admet-442	86	6	suggested	suggest	VERB
admet-442	86	7	that	that	SCONJ
admet-442	86	8	pd	pd	PROPN
admet-442	86	9	-	-	PROPN
admet-442	86	10	l1	l1	PROPN
admet-442	86	11	can	can	AUX
admet-442	86	12	inhibit	inhibit	VERB
admet-442	86	13	the	the	DET
admet-442	86	14	immune	immune	ADJ
admet-442	86	15	response	response	NOUN
admet-442	86	16	during	during	ADP
admet-442	86	17	chronic	chronic	ADJ
admet-442	86	18	viral	viral	ADJ
admet-442	86	19	infection	infection	NOUN
admet-442	86	20	[	[	X
admet-442	86	21	54	54	NUM
admet-442	86	22	]	]	SYM
admet-442	86	23	.	.	PUNCT
admet-442	87	1	pd	pd	PROPN
admet-442	87	2	-	-	PROPN
admet-442	87	3	l1	l1	PROPN
admet-442	87	4	was	be	AUX
admet-442	87	5	involved	involve	VERB
admet-442	87	6	in	in	ADP
admet-442	87	7	intestinal	intestinal	ADJ
admet-442	87	8	mucosal	mucosal	NOUN
admet-442	87	9	inflammation	inflammation	NOUN
admet-442	87	10	,	,	PUNCT
admet-442	87	11	such	such	ADJ
admet-442	87	12	as	as	ADP
admet-442	87	13	ulcerative	ulcerative	ADJ
admet-442	87	14	colitis	colitis	NOUN
admet-442	87	15	.	.	PUNCT
admet-442	88	1	in	in	ADP
admet-442	88	2	severe	severe	ADJ
admet-442	88	3	combined	combined	ADJ
admet-442	88	4	immune	immune	NOUN
admet-442	88	5	-	-	PUNCT
admet-442	88	6	deficient	deficient	ADJ
admet-442	88	7	(	(	PUNCT
admet-442	88	8	scid	scid	NOUN
admet-442	88	9	)	)	PUNCT
admet-442	88	10	mice	mouse	NOUN
admet-442	88	11	,	,	PUNCT
admet-442	88	12	which	which	PRON
admet-442	88	13	were	be	AUX
admet-442	88	14	reconstituted	reconstitute	VERB
admet-442	88	15	with	with	ADP
admet-442	88	16	cd45rbhigh	cd45rbhigh	PROPN
admet-442	88	17	cd4	cd4	PROPN
admet-442	88	18	+	+	PROPN
admet-442	88	19	t	t	NOUN
admet-442	88	20	cells	cell	NOUN
admet-442	88	21	,	,	PUNCT
admet-442	88	22	blockade	blockade	NOUN
admet-442	88	23	of	of	ADP
admet-442	88	24	pd	pd	PROPN
admet-442	88	25	-	-	PROPN
admet-442	88	26	l1	l1	PROPN
admet-442	88	27	by	by	ADP
admet-442	88	28	mabs	mab	NOUN
admet-442	88	29	against	against	ADP
admet-442	88	30	b7	b7	PROPN
admet-442	88	31	-	-	PUNCT
admet-442	88	32	h1	h1	PROPN
admet-442	88	33	suppressed	suppress	VERB
admet-442	88	34	wasting	waste	VERB
admet-442	88	35	disease	disease	NOUN
admet-442	88	36	with	with	ADP
admet-442	88	37	colitis	colitis	NOUN
admet-442	88	38	[	[	X
admet-442	88	39	45	45	NUM
admet-442	88	40	]	]	PUNCT
admet-442	88	41	.	.	PUNCT
admet-442	89	1	role	role	NOUN
admet-442	89	2	of	of	ADP
admet-442	89	3	pd	pd	PROPN
admet-442	89	4	-	-	PROPN
admet-442	89	5	l1	l1	PROPN
admet-442	89	6	in	in	ADP
admet-442	89	7	efficacy	efficacy	NOUN
admet-442	89	8	of	of	ADP
admet-442	89	9	treatment	treatment	NOUN
admet-442	89	10	pre	pre	ADJ
admet-442	89	11	-	-	ADJ
admet-442	89	12	clinical	clinical	ADJ
admet-442	89	13	data	datum	NOUN
admet-442	89	14	showed	show	VERB
admet-442	89	15	that	that	SCONJ
admet-442	89	16	the	the	DET
admet-442	89	17	anticancer	anticancer	NOUN
admet-442	89	18	effect	effect	NOUN
admet-442	89	19	of	of	ADP
admet-442	89	20	anti	anti	ADJ
admet-442	89	21	-	-	ADJ
admet-442	89	22	pd	pd	ADJ
admet-442	89	23	-	-	PUNCT
admet-442	89	24	l1	l1	PROPN
admet-442	89	25	antibody	antibody	NOUN
admet-442	89	26	is	be	AUX
admet-442	89	27	different	different	ADJ
admet-442	89	28	kinds	kind	NOUN
admet-442	89	29	of	of	ADP
admet-442	89	30	cancer	cancer	NOUN
admet-442	89	31	cells	cell	NOUN
admet-442	89	32	.	.	PUNCT
admet-442	90	1	meanwhile	meanwhile	ADV
admet-442	90	2	,	,	PUNCT
admet-442	90	3	clinical	clinical	ADJ
admet-442	90	4	activity	activity	NOUN
admet-442	90	5	of	of	ADP
admet-442	90	6	anti	anti	ADJ
admet-442	90	7	-	-	ADJ
admet-442	90	8	pd	pd	ADJ
admet-442	90	9	-	-	PUNCT
admet-442	90	10	l1	l1	PROPN
admet-442	90	11	antibodies	antibody	NOUN
admet-442	90	12	has	have	AUX
admet-442	90	13	been	be	AUX
admet-442	90	14	observed	observe	VERB
admet-442	90	15	in	in	ADP
admet-442	90	16	various	various	ADJ
admet-442	90	17	malignancies	malignancy	NOUN
admet-442	90	18	,	,	PUNCT
admet-442	90	19	such	such	ADJ
admet-442	90	20	as	as	ADP
admet-442	90	21	melanoma	melanoma	NOUN
admet-442	90	22	,	,	PUNCT
admet-442	90	23	non	non	ADJ
admet-442	90	24	-	-	ADJ
admet-442	90	25	small	small	ADJ
admet-442	90	26	cell	cell	NOUN
admet-442	90	27	lung	lung	NOUN
admet-442	90	28	cancer	cancer	NOUN
admet-442	90	29	,	,	PUNCT
admet-442	90	30	squamous	squamous	ADJ
admet-442	90	31	head	head	NOUN
admet-442	90	32	and	and	CCONJ
admet-442	90	33	neck	neck	NOUN
admet-442	90	34	cancer	cancer	NOUN
admet-442	90	35	,	,	PUNCT
admet-442	90	36	microsatellite	microsatellite	ADJ
admet-442	90	37	-	-	PUNCT
admet-442	90	38	unstable	unstable	ADJ
admet-442	90	39	guo	guo	NOUN
admet-442	90	40	,	,	PUNCT
admet-442	90	41	lin	lin	PROPN
admet-442	90	42	and	and	CCONJ
admet-442	90	43	kwok	kwok	PROPN
admet-442	90	44	admet	admet	PROPN
admet-442	90	45	&	&	CCONJ
admet-442	90	46	dmpk	dmpk	PROPN
admet-442	90	47	5(3	5(3	NUM
admet-442	90	48	)	)	PUNCT
admet-442	90	49	(	(	PUNCT
admet-442	90	50	2017	2017	NUM
admet-442	90	51	)	)	PUNCT
admet-442	90	52	159	159	NUM
admet-442	90	53	-	-	SYM
admet-442	90	54	172	172	NUM
admet-442	90	55	162	162	NUM
admet-442	90	56	colorectal	colorectal	ADJ
admet-442	90	57	cancer	cancer	NOUN
admet-442	90	58	,	,	PUNCT
admet-442	90	59	and	and	CCONJ
admet-442	90	60	other	other	ADJ
admet-442	90	61	types	type	NOUN
admet-442	90	62	of	of	ADP
admet-442	90	63	cancers	cancer	NOUN
admet-442	90	64	[	[	X
admet-442	90	65	55	55	NUM
admet-442	90	66	-	-	SYM
admet-442	90	67	58	58	NUM
admet-442	90	68	]	]	PUNCT
admet-442	90	69	.	.	PUNCT
admet-442	91	1	a	a	DET
admet-442	91	2	predictive	predictive	ADJ
admet-442	91	3	role	role	NOUN
admet-442	91	4	of	of	ADP
admet-442	91	5	pd	pd	PROPN
admet-442	91	6	-	-	PROPN
admet-442	91	7	l1	l1	PROPN
admet-442	91	8	expression	expression	NOUN
admet-442	91	9	and	and	CCONJ
admet-442	91	10	til	til	ADV
admet-442	91	11	(	(	PUNCT
admet-442	91	12	tumor	tumor	NOUN
admet-442	91	13	infiltrating	infiltrate	VERB
admet-442	91	14	lymphocytes	lymphocyte	NOUN
admet-442	91	15	)	)	PUNCT
admet-442	91	16	has	have	AUX
admet-442	91	17	been	be	AUX
admet-442	91	18	found	find	VERB
admet-442	91	19	in	in	ADP
admet-442	91	20	lung	lung	NOUN
admet-442	91	21	cancer	cancer	NOUN
admet-442	91	22	patients	patient	NOUN
admet-442	91	23	receiving	receive	VERB
admet-442	91	24	anti	anti	ADJ
admet-442	91	25	-	-	ADJ
admet-442	91	26	pd-1	pd-1	ADJ
admet-442	91	27	/	/	SYM
admet-442	91	28	pd	pd	NOUN
admet-442	91	29	-	-	PROPN
admet-442	91	30	l1	l1	PROPN
admet-442	91	31	immunotherapy	immunotherapy	NOUN
admet-442	91	32	and	and	CCONJ
admet-442	91	33	could	could	AUX
admet-442	91	34	be	be	AUX
admet-442	91	35	used	use	VERB
admet-442	91	36	to	to	PART
admet-442	91	37	improve	improve	VERB
admet-442	91	38	clinical	clinical	ADJ
admet-442	91	39	interpretations	interpretation	NOUN
admet-442	92	1	[	[	X
admet-442	92	2	59	59	NUM
admet-442	92	3	]	]	PUNCT
admet-442	92	4	.	.	PUNCT
admet-442	93	1	however	however	ADV
admet-442	93	2	,	,	PUNCT
admet-442	93	3	pd	pd	PROPN
admet-442	93	4	-	-	PUNCT
admet-442	93	5	l1	l1	PROPN
admet-442	93	6	expression	expression	NOUN
admet-442	93	7	can	can	AUX
admet-442	93	8	be	be	AUX
admet-442	93	9	constitutive	constitutive	ADJ
admet-442	93	10	and	and	CCONJ
admet-442	93	11	inducible	inducible	ADJ
admet-442	93	12	.	.	PUNCT
admet-442	94	1	induced	induce	VERB
admet-442	94	2	pd	pd	PROPN
admet-442	94	3	-	-	PUNCT
admet-442	94	4	l1	l1	PROPN
admet-442	94	5	upregulation	upregulation	NOUN
admet-442	94	6	is	be	AUX
admet-442	94	7	regulated	regulate	VERB
admet-442	94	8	by	by	ADP
admet-442	94	9	various	various	ADJ
admet-442	94	10	other	other	ADJ
admet-442	94	11	cytokines	cytokine	NOUN
admet-442	94	12	,	,	PUNCT
admet-442	94	13	such	such	ADJ
admet-442	94	14	as	as	ADP
admet-442	94	15	ifn	ifn	PROPN
admet-442	94	16	,	,	PUNCT
admet-442	94	17	tumor	tumor	NOUN
admet-442	94	18	necrosis	necrosis	NOUN
admet-442	94	19	factor	factor	NOUN
admet-442	94	20	(	(	PUNCT
admet-442	94	21	tnf)-α	tnf)-α	NOUN
admet-442	94	22	and	and	CCONJ
admet-442	94	23	toll	toll	NOUN
admet-442	94	24	-	-	PUNCT
admet-442	94	25	like	like	ADJ
admet-442	94	26	receptor	receptor	NOUN
admet-442	94	27	(	(	PUNCT
admet-442	94	28	tlr	tlr	PROPN
admet-442	94	29	)	)	PUNCT
admet-442	94	30	etc	etc	X
admet-442	94	31	.	.	PUNCT
admet-442	95	1	[	[	X
admet-442	95	2	60	60	NUM
admet-442	95	3	]	]	PUNCT
admet-442	95	4	.	.	PUNCT
admet-442	96	1	most	most	ADV
admet-442	96	2	importantly	importantly	ADV
admet-442	96	3	,	,	PUNCT
admet-442	96	4	pd	pd	PROPN
admet-442	96	5	-	-	PUNCT
admet-442	96	6	l1	l1	PROPN
admet-442	96	7	upregulation	upregulation	NOUN
admet-442	96	8	can	can	AUX
admet-442	96	9	also	also	ADV
admet-442	96	10	improve	improve	VERB
admet-442	96	11	survival	survival	NOUN
admet-442	96	12	of	of	ADP
admet-442	96	13	mice	mouse	NOUN
admet-442	96	14	with	with	ADP
admet-442	96	15	lung	lung	NOUN
admet-442	96	16	tumor	tumor	NOUN
admet-442	96	17	,	,	PUNCT
admet-442	96	18	which	which	PRON
admet-442	96	19	received	receive	VERB
admet-442	96	20	anti	anti	ADJ
admet-442	96	21	-	-	ADJ
admet-442	96	22	pd	pd	ADJ
admet-442	96	23	-	-	ADJ
admet-442	96	24	l1	l1	PROPN
admet-442	96	25	treatment	treatment	NOUN
admet-442	96	26	[	[	X
admet-442	96	27	61	61	NUM
admet-442	96	28	]	]	PUNCT
admet-442	96	29	.	.	PUNCT
admet-442	97	1	this	this	DET
admet-442	97	2	review	review	NOUN
admet-442	97	3	will	will	AUX
admet-442	97	4	discuss	discuss	VERB
admet-442	97	5	the	the	DET
admet-442	97	6	basic	basic	ADJ
admet-442	97	7	structure	structure	NOUN
admet-442	97	8	of	of	ADP
admet-442	97	9	pd	pd	PROPN
admet-442	97	10	-	-	PROPN
admet-442	97	11	l1	l1	PROPN
admet-442	97	12	,	,	PUNCT
admet-442	97	13	which	which	PRON
admet-442	97	14	is	be	AUX
admet-442	97	15	important	important	ADJ
admet-442	97	16	for	for	ADP
admet-442	97	17	pd	pd	PROPN
admet-442	97	18	-	-	PUNCT
admet-442	97	19	l1	l1	PROPN
admet-442	97	20	regulation	regulation	NOUN
admet-442	97	21	and	and	CCONJ
admet-442	97	22	therapy	therapy	NOUN
admet-442	97	23	.	.	PUNCT
admet-442	98	1	besides	besides	SCONJ
admet-442	98	2	,	,	PUNCT
admet-442	98	3	this	this	DET
admet-442	98	4	review	review	NOUN
admet-442	98	5	will	will	AUX
admet-442	98	6	also	also	ADV
admet-442	98	7	discuss	discuss	VERB
admet-442	98	8	regulation	regulation	NOUN
admet-442	98	9	and	and	CCONJ
admet-442	98	10	signaling	signal	VERB
admet-442	98	11	pathway	pathway	NOUN
admet-442	98	12	of	of	ADP
admet-442	98	13	pd	pd	PROPN
admet-442	98	14	-	-	PROPN
admet-442	98	15	l1	l1	PROPN
admet-442	98	16	,	,	PUNCT
admet-442	98	17	which	which	PRON
admet-442	98	18	can	can	AUX
admet-442	98	19	influence	influence	VERB
admet-442	98	20	anti	anti	ADJ
admet-442	98	21	-	-	ADJ
admet-442	98	22	pd	pd	ADJ
admet-442	98	23	-	-	PROPN
admet-442	98	24	l1	l1	PROPN
admet-442	98	25	immunotherapy	immunotherapy	NOUN
admet-442	98	26	.	.	PUNCT
admet-442	99	1	structure	structure	NOUN
admet-442	99	2	of	of	ADP
admet-442	99	3	pd	pd	PROPN
admet-442	99	4	-	-	PROPN
admet-442	99	5	l1	l1	PROPN
admet-442	99	6	pd	pd	PROPN
admet-442	99	7	-	-	PROPN
admet-442	99	8	l1	l1	PROPN
admet-442	99	9	was	be	AUX
admet-442	99	10	found	find	VERB
admet-442	99	11	by	by	ADP
admet-442	99	12	searching	search	VERB
admet-442	99	13	the	the	DET
admet-442	99	14	expressed	express	VERB
admet-442	99	15	sequence	sequence	NOUN
admet-442	99	16	tag	tag	NOUN
admet-442	99	17	database	database	NOUN
admet-442	99	18	(	(	PUNCT
admet-442	99	19	generated	generate	VERB
admet-442	99	20	from	from	ADP
admet-442	99	21	dendritic	dendritic	ADJ
admet-442	99	22	cells	cell	NOUN
admet-442	99	23	and	and	CCONJ
admet-442	99	24	activated	activate	VERB
admet-442	99	25	macrophages	macrophage	NOUN
admet-442	99	26	)	)	PUNCT
admet-442	99	27	for	for	ADP
admet-442	99	28	molecules	molecule	NOUN
admet-442	99	29	which	which	PRON
admet-442	99	30	contain	contain	VERB
admet-442	99	31	homology	homology	NOUN
admet-442	99	32	to	to	ADP
admet-442	99	33	b7	b7	PROPN
admet-442	99	34	-	-	PUNCT
admet-442	99	35	1	1	NUM
admet-442	99	36	and	and	CCONJ
admet-442	99	37	b7	b7	PROPN
admet-442	99	38	-	-	PUNCT
admet-442	99	39	2	2	NUM
admet-442	100	1	[	[	X
admet-442	100	2	62	62	NUM
admet-442	100	3	]	]	PUNCT
admet-442	100	4	.	.	PUNCT
admet-442	101	1	pd	pd	PROPN
admet-442	101	2	-	-	PROPN
admet-442	101	3	l1	l1	PROPN
admet-442	101	4	is	be	AUX
admet-442	101	5	encoded	encode	VERB
admet-442	101	6	by	by	ADP
admet-442	101	7	the	the	DET
admet-442	101	8	cd274	cd274	PROPN
admet-442	101	9	gene	gene	NOUN
admet-442	101	10	,	,	PUNCT
admet-442	101	11	which	which	PRON
admet-442	101	12	is	be	AUX
admet-442	101	13	situated	situate	VERB
admet-442	101	14	on	on	ADP
admet-442	101	15	mouse	mouse	NOUN
admet-442	101	16	chromosome	chromosome	NOUN
admet-442	101	17	19	19	NUM
admet-442	101	18	and	and	CCONJ
admet-442	101	19	human	human	ADJ
admet-442	101	20	chromosome	chromosome	NOUN
admet-442	101	21	9	9	NUM
admet-442	101	22	at	at	ADP
admet-442	101	23	a	a	DET
admet-442	101	24	band	band	NOUN
admet-442	101	25	p24	p24	NOUN
admet-442	101	26	.	.	PUNCT
admet-442	102	1	pd	pd	PROPN
admet-442	102	2	-	-	PROPN
admet-442	102	3	l1	l1	PROPN
admet-442	102	4	is	be	AUX
admet-442	102	5	a	a	DET
admet-442	102	6	40kda	40kda	NOUN
admet-442	102	7	protein	protein	NOUN
admet-442	102	8	containing	contain	VERB
admet-442	102	9	290	290	NUM
admet-442	102	10	amino	amino	NOUN
admet-442	102	11	acid	acid	NOUN
admet-442	102	12	.	.	PUNCT
admet-442	103	1	human	human	ADJ
admet-442	103	2	pd	pd	PROPN
admet-442	103	3	-	-	PROPN
admet-442	103	4	l1	l1	PROPN
admet-442	103	5	shares	share	VERB
admet-442	103	6	70	70	NUM
admet-442	103	7	%	%	NOUN
admet-442	103	8	homology	homology	NOUN
admet-442	103	9	in	in	ADP
admet-442	103	10	amino	amino	ADJ
admet-442	103	11	acids	acid	NOUN
admet-442	103	12	with	with	ADP
admet-442	103	13	mouse	mouse	PROPN
admet-442	103	14	pd	pd	PROPN
admet-442	103	15	-	-	PROPN
admet-442	103	16	l1	l1	PROPN
admet-442	103	17	[	[	X
admet-442	103	18	63	63	NUM
admet-442	103	19	]	]	PUNCT
admet-442	103	20	.	.	PUNCT
admet-442	104	1	mazanet	mazanet	PROPN
admet-442	104	2	et	et	PROPN
admet-442	104	3	al	al	PROPN
admet-442	104	4	.	.	PROPN
admet-442	104	5	reported	report	VERB
admet-442	104	6	that	that	SCONJ
admet-442	104	7	the	the	DET
admet-442	104	8	promoter	promoter	NOUN
admet-442	104	9	region	region	NOUN
admet-442	104	10	of	of	ADP
admet-442	104	11	cd274	cd274	PROPN
admet-442	104	12	gene	gene	NOUN
admet-442	104	13	consisted	consist	VERB
admet-442	104	14	several	several	ADJ
admet-442	104	15	elements	element	NOUN
admet-442	104	16	responded	respond	VERB
admet-442	104	17	to	to	ADP
admet-442	104	18	ifn	ifn	NOUN
admet-442	104	19	-	-	PUNCT
admet-442	104	20	γ	γ	NOUN
admet-442	104	21	,	,	PUNCT
admet-442	104	22	which	which	PRON
admet-442	104	23	was	be	AUX
admet-442	104	24	necessary	necessary	ADJ
admet-442	104	25	for	for	ADP
admet-442	104	26	upregulation	upregulation	NOUN
admet-442	104	27	of	of	ADP
admet-442	104	28	pd	pd	PROPN
admet-442	104	29	-	-	PROPN
admet-442	104	30	l1	l1	PROPN
admet-442	104	31	expression	expression	NOUN
admet-442	104	32	mediated	mediate	VERB
admet-442	104	33	by	by	ADP
admet-442	104	34	ifn	ifn	PROPN
admet-442	104	35	-	-	PUNCT
admet-442	104	36	γ	γ	NOUN
admet-442	104	37	[	[	X
admet-442	104	38	64	64	NUM
admet-442	104	39	]	]	PUNCT
admet-442	104	40	.	.	PUNCT
admet-442	105	1	pd	pd	PROPN
admet-442	105	2	-	-	PROPN
admet-442	105	3	l1	l1	PROPN
admet-442	105	4	exerts	exert	VERB
admet-442	105	5	a	a	DET
admet-442	105	6	role	role	NOUN
admet-442	105	7	as	as	ADP
admet-442	105	8	a	a	DET
admet-442	105	9	type	type	NOUN
admet-442	105	10	i	i	PRON
admet-442	105	11	transmembrane	transmembrane	ADJ
admet-442	105	12	protein	protein	NOUN
admet-442	105	13	and	and	CCONJ
admet-442	105	14	contains	contain	VERB
admet-442	105	15	four	four	NUM
admet-442	105	16	domains	domain	NOUN
admet-442	105	17	[	[	X
admet-442	105	18	56	56	NUM
admet-442	105	19	]	]	PUNCT
admet-442	105	20	.	.	PUNCT
admet-442	106	1	they	they	PRON
admet-442	106	2	are	be	AUX
admet-442	106	3	ig	ig	PROPN
admet-442	106	4	(	(	PUNCT
admet-442	106	5	immunoglobulin	immunoglobulin	NOUN
admet-442	106	6	)	)	PUNCT
admet-442	106	7	v	v	NOUN
admet-442	106	8	-	-	PUNCT
admet-442	106	9	like	like	ADJ
admet-442	106	10	domain	domain	NOUN
admet-442	106	11	,	,	PUNCT
admet-442	106	12	ig	ig	PROPN
admet-442	106	13	c	c	NOUN
admet-442	106	14	-	-	PUNCT
admet-442	106	15	like	like	ADJ
admet-442	106	16	domain	domain	NOUN
admet-442	106	17	,	,	PUNCT
admet-442	106	18	and	and	CCONJ
admet-442	106	19	hydrophobic	hydrophobic	NOUN
admet-442	106	20	transmembrane	transmembrane	NOUN
admet-442	106	21	domain	domain	NOUN
admet-442	106	22	,	,	PUNCT
admet-442	106	23	as	as	ADV
admet-442	106	24	well	well	ADV
admet-442	106	25	as	as	ADP
admet-442	106	26	cytoplasmic	cytoplasmic	ADJ
admet-442	106	27	domains	domain	NOUN
admet-442	106	28	,	,	PUNCT
admet-442	106	29	encoded	encode	VERB
admet-442	106	30	by	by	ADP
admet-442	106	31	single	single	ADJ
admet-442	106	32	exon	exon	NOUN
admet-442	106	33	sequences	sequence	NOUN
admet-442	106	34	[	[	X
admet-442	106	35	62	62	NUM
admet-442	106	36	]	]	PUNCT
admet-442	106	37	.	.	PUNCT
admet-442	107	1	the	the	DET
admet-442	107	2	schematic	schematic	ADJ
admet-442	107	3	diagram	diagram	NOUN
admet-442	107	4	and	and	CCONJ
admet-442	107	5	structure	structure	NOUN
admet-442	107	6	of	of	ADP
admet-442	107	7	pdl1	pdl1	PROPN
admet-442	107	8	is	be	AUX
admet-442	107	9	shown	show	VERB
admet-442	107	10	in	in	ADP
admet-442	107	11	figure	figure	NOUN
admet-442	107	12	1	1	NUM
admet-442	107	13	.	.	PUNCT
admet-442	108	1	the	the	DET
admet-442	108	2	ig	ig	PROPN
admet-442	108	3	v	v	PROPN
admet-442	108	4	-	-	PUNCT
admet-442	108	5	like	like	ADJ
admet-442	108	6	domain	domain	NOUN
admet-442	108	7	and	and	CCONJ
admet-442	108	8	ig	ig	ADP
admet-442	108	9	c	c	NOUN
admet-442	108	10	-	-	PUNCT
admet-442	108	11	like	like	ADJ
admet-442	108	12	domain	domain	NOUN
admet-442	108	13	are	be	AUX
admet-442	108	14	two	two	NUM
admet-442	108	15	anti	anti	ADJ
admet-442	108	16	-	-	ADJ
admet-442	108	17	parallel	parallel	ADJ
admet-442	108	18	β	β	X
admet-442	108	19	sandwich	sandwich	NOUN
admet-442	108	20	immunoglobulin	immunoglobulin	NOUN
admet-442	108	21	superfamily	superfamily	ADV
admet-442	108	22	(	(	PUNCT
admet-442	108	23	ig	ig	PROPN
admet-442	108	24	sf	sf	PROPN
admet-442	108	25	)	)	PUNCT
admet-442	108	26	domains	domain	NOUN
admet-442	108	27	,	,	PUNCT
admet-442	108	28	which	which	PRON
admet-442	108	29	are	be	AUX
admet-442	108	30	related	relate	VERB
admet-442	108	31	to	to	ADP
admet-442	108	32	domains	domain	NOUN
admet-442	108	33	of	of	ADP
admet-442	108	34	immunoglobulins	immunoglobulin	NOUN
admet-442	108	35	[	[	X
admet-442	108	36	65	65	NUM
admet-442	108	37	,	,	PUNCT
admet-442	108	38	66	66	NUM
admet-442	108	39	]	]	PUNCT
admet-442	108	40	.	.	PUNCT
admet-442	109	1	the	the	DET
admet-442	109	2	ig	ig	PROPN
admet-442	109	3	v	v	PROPN
admet-442	109	4	-	-	PUNCT
admet-442	109	5	like	like	ADJ
admet-442	109	6	domain	domain	NOUN
admet-442	109	7	is	be	AUX
admet-442	109	8	formed	form	VERB
admet-442	109	9	by	by	ADP
admet-442	109	10	bed	bed	NOUN
admet-442	109	11	and	and	CCONJ
admet-442	109	12	agfcc’c	agfcc’c	ADJ
admet-442	109	13	’’	’'	PUNCT
admet-442	109	14	β	β	NOUN
admet-442	109	15	sheets	sheet	NOUN
admet-442	109	16	,	,	PUNCT
admet-442	109	17	and	and	CCONJ
admet-442	109	18	necessary	necessary	ADJ
admet-442	109	19	for	for	ADP
admet-442	109	20	interaction	interaction	NOUN
admet-442	109	21	of	of	ADP
admet-442	109	22	pd	pd	PROPN
admet-442	109	23	-	-	PROPN
admet-442	109	24	l1	l1	PROPN
admet-442	109	25	and	and	CCONJ
admet-442	109	26	b7	b7	PROPN
admet-442	109	27	-	-	PUNCT
admet-442	109	28	1	1	NUM
admet-442	109	29	in	in	ADP
admet-442	109	30	murine	murine	NOUN
admet-442	109	31	[	[	X
admet-442	109	32	67	67	NUM
admet-442	109	33	]	]	PUNCT
admet-442	109	34	.	.	PUNCT
admet-442	110	1	what	what	PRON
admet-442	110	2	’s	’	VERB
admet-442	110	3	more	more	ADJ
admet-442	110	4	,	,	PUNCT
admet-442	110	5	the	the	DET
admet-442	110	6	pd	pd	PROPN
admet-442	110	7	-	-	PUNCT
admet-442	110	8	l1	l1	PROPN
admet-442	110	9	:	:	PUNCT
admet-442	110	10	pd-1	pd-1	VERB
admet-442	110	11	binding	bind	VERB
admet-442	110	12	interface	interface	NOUN
admet-442	110	13	is	be	AUX
admet-442	110	14	also	also	ADV
admet-442	110	15	on	on	ADP
admet-442	110	16	its	its	PRON
admet-442	110	17	ig	ig	PROPN
admet-442	110	18	v	v	NOUN
admet-442	110	19	-	-	PUNCT
admet-442	110	20	like	like	ADJ
admet-442	110	21	domain	domain	NOUN
admet-442	110	22	.	.	PUNCT
admet-442	111	1	the	the	DET
admet-442	111	2	ig	ig	PROPN
admet-442	111	3	c	c	PROPN
admet-442	111	4	domain	domain	NOUN
admet-442	111	5	of	of	ADP
admet-442	111	6	pd	pd	PROPN
admet-442	111	7	-	-	PROPN
admet-442	111	8	l1	l1	PROPN
admet-442	111	9	has	have	VERB
admet-442	111	10	c1	c1	NOUN
admet-442	111	11	-	-	PUNCT
admet-442	111	12	set	set	VERB
admet-442	111	13	domains	domain	NOUN
admet-442	111	14	with	with	ADP
admet-442	111	15	β	β	NOUN
admet-442	111	16	-	-	PUNCT
admet-442	111	17	strands	strand	NOUN
admet-442	111	18	forming	form	VERB
admet-442	111	19	abed	abe	VERB
admet-442	111	20	and	and	CCONJ
admet-442	111	21	cfg	cfg	NOUN
admet-442	111	22	sheets	sheet	NOUN
admet-442	111	23	[	[	X
admet-442	111	24	66	66	NUM
admet-442	111	25	]	]	PUNCT
admet-442	111	26	.	.	PUNCT
admet-442	112	1	the	the	DET
admet-442	112	2	cytoplasmic	cytoplasmic	ADJ
admet-442	112	3	domain	domain	NOUN
admet-442	112	4	which	which	PRON
admet-442	112	5	is	be	AUX
admet-442	112	6	encoded	encode	VERB
admet-442	112	7	by	by	ADP
admet-442	112	8	the	the	DET
admet-442	112	9	last	last	ADJ
admet-442	112	10	exon	exon	NOUN
admet-442	112	11	is	be	AUX
admet-442	112	12	about	about	ADV
admet-442	112	13	30	30	NUM
admet-442	112	14	amino	amino	NOUN
admet-442	112	15	acids	acid	NOUN
admet-442	112	16	,	,	PUNCT
admet-442	112	17	and	and	CCONJ
admet-442	112	18	highly	highly	ADV
admet-442	112	19	conserved	conserve	VERB
admet-442	112	20	in	in	ADP
admet-442	112	21	all	all	DET
admet-442	112	22	species	specie	NOUN
admet-442	112	23	reported	report	VERB
admet-442	112	24	[	[	X
admet-442	112	25	23	23	NUM
admet-442	112	26	]	]	PUNCT
admet-442	112	27	.	.	PUNCT
admet-442	113	1	while	while	SCONJ
admet-442	113	2	a	a	DET
admet-442	113	3	potential	potential	ADJ
admet-442	113	4	site	site	NOUN
admet-442	113	5	of	of	ADP
admet-442	113	6	pd	pd	PROPN
admet-442	113	7	-	-	PROPN
admet-442	113	8	l1	l1	PROPN
admet-442	113	9	which	which	PRON
admet-442	113	10	could	could	AUX
admet-442	113	11	be	be	AUX
admet-442	113	12	phosphorylated	phosphorylate	VERB
admet-442	113	13	by	by	ADP
admet-442	113	14	protein	protein	NOUN
admet-442	113	15	kinase	kinase	PROPN
admet-442	113	16	c	c	PROPN
admet-442	113	17	(	(	PUNCT
admet-442	113	18	pkc	pkc	NOUN
admet-442	113	19	)	)	PUNCT
admet-442	113	20	is	be	AUX
admet-442	113	21	on	on	ADP
admet-442	113	22	its	its	PRON
admet-442	113	23	intracellular	intracellular	ADJ
admet-442	113	24	domain	domain	NOUN
admet-442	113	25	[	[	X
admet-442	113	26	23	23	NUM
admet-442	113	27	]	]	PUNCT
admet-442	113	28	.	.	PUNCT
admet-442	114	1	regulation	regulation	NOUN
admet-442	114	2	of	of	ADP
admet-442	114	3	pd	pd	PROPN
admet-442	114	4	-	-	PROPN
admet-442	114	5	l1	l1	PROPN
admet-442	114	6	pd	pd	PROPN
admet-442	114	7	-	-	PROPN
admet-442	114	8	l1	l1	PROPN
admet-442	114	9	expression	expression	NOUN
admet-442	114	10	is	be	AUX
admet-442	114	11	present	present	ADJ
admet-442	114	12	on	on	ADP
admet-442	114	13	antigen	antigen	ADV
admet-442	114	14	-	-	PUNCT
admet-442	114	15	presenting	present	VERB
admet-442	114	16	cells	cell	NOUN
admet-442	114	17	(	(	PUNCT
admet-442	114	18	apcs	apc	NOUN
admet-442	114	19	)	)	PUNCT
admet-442	114	20	,	,	PUNCT
admet-442	114	21	such	such	ADJ
admet-442	114	22	as	as	ADP
admet-442	114	23	human	human	ADJ
admet-442	114	24	monocytes	monocyte	NOUN
admet-442	114	25	,	,	PUNCT
admet-442	114	26	as	as	ADV
admet-442	114	27	well	well	ADV
admet-442	114	28	as	as	ADP
admet-442	114	29	activated	activate	VERB
admet-442	114	30	human	human	ADJ
admet-442	114	31	and	and	CCONJ
admet-442	114	32	murine	murine	ADJ
admet-442	114	33	dendritic	dendritic	ADJ
admet-442	114	34	cells	cell	NOUN
admet-442	114	35	.	.	PUNCT
admet-442	115	1	moreover	moreover	ADV
admet-442	115	2	,	,	PUNCT
admet-442	115	3	pd	pd	PROPN
admet-442	115	4	-	-	PROPN
admet-442	115	5	l1	l1	PROPN
admet-442	115	6	is	be	AUX
admet-442	115	7	also	also	ADV
admet-442	115	8	expressed	express	VERB
admet-442	115	9	in	in	ADP
admet-442	115	10	nonlymphoid	nonlymphoid	ADJ
admet-442	115	11	tissues	tissue	NOUN
admet-442	115	12	such	such	ADJ
admet-442	115	13	as	as	ADP
admet-442	115	14	heart	heart	NOUN
admet-442	115	15	and	and	CCONJ
admet-442	115	16	lung	lung	NOUN
admet-442	115	17	,	,	PUNCT
admet-442	115	18	thymus	thymus	VERB
admet-442	115	19	,	,	PUNCT
admet-442	115	20	kidney	kidney	PROPN
admet-442	115	21	.	.	PUNCT
admet-442	116	1	pd	pd	PROPN
admet-442	116	2	-	-	PROPN
admet-442	116	3	l1	l1	PROPN
admet-442	116	4	is	be	AUX
admet-442	116	5	easily	easily	ADV
admet-442	116	6	induced	induce	VERB
admet-442	116	7	by	by	ADP
admet-442	116	8	pro	pro	ADJ
admet-442	116	9	-	-	ADJ
admet-442	116	10	inflammatory	inflammatory	ADJ
admet-442	116	11	cytokines	cytokine	NOUN
admet-442	116	12	on	on	ADP
admet-442	116	13	different	different	ADJ
admet-442	116	14	kinds	kind	NOUN
admet-442	116	15	of	of	ADP
admet-442	116	16	cells	cell	NOUN
admet-442	116	17	,	,	PUNCT
admet-442	116	18	which	which	PRON
admet-442	116	19	is	be	AUX
admet-442	116	20	shown	show	VERB
admet-442	116	21	in	in	ADP
admet-442	116	22	figure	figure	NOUN
admet-442	116	23	2	2	NUM
admet-442	116	24	.	.	PUNCT
admet-442	116	25	pd	pd	PROPN
admet-442	116	26	-	-	PROPN
admet-442	116	27	l1	l1	PROPN
admet-442	116	28	can	can	AUX
admet-442	116	29	be	be	AUX
admet-442	116	30	induced	induce	VERB
admet-442	116	31	by	by	ADP
admet-442	116	32	ifn	ifn	PROPN
admet-442	116	33	-	-	PUNCT
admet-442	116	34	γ	γ	NOUN
admet-442	116	35	and	and	CCONJ
admet-442	116	36	tlr	tlr	PROPN
admet-442	116	37	ligands	ligand	NOUN
admet-442	116	38	in	in	ADP
admet-442	116	39	mm	mm	NOUN
admet-442	116	40	plasma	plasma	NOUN
admet-442	116	41	cells	cell	NOUN
admet-442	117	1	[	[	X
admet-442	117	2	20	20	NUM
admet-442	117	3	]	]	PUNCT
admet-442	117	4	.	.	PUNCT
admet-442	118	1	this	this	DET
admet-442	118	2	study	study	NOUN
admet-442	118	3	revealed	reveal	VERB
admet-442	118	4	that	that	SCONJ
admet-442	118	5	blockade	blockade	NOUN
admet-442	118	6	of	of	ADP
admet-442	118	7	mitogen	mitogen	NOUN
admet-442	118	8	-	-	PUNCT
admet-442	118	9	activated	activate	VERB
admet-442	118	10	protein	protein	NOUN
admet-442	118	11	kinase	kinase	NOUN
admet-442	118	12	(	(	PUNCT
admet-442	118	13	mapk)/erk	mapk)/erk	NOUN
admet-442	118	14	pathway	pathway	NOUN
admet-442	118	15	and	and	CCONJ
admet-442	118	16	inhibition	inhibition	NOUN
admet-442	118	17	of	of	ADP
admet-442	118	18	signal	signal	ADJ
admet-442	118	19	transducer	transducer	NOUN
admet-442	118	20	and	and	CCONJ
admet-442	118	21	activator	activator	NOUN
admet-442	118	22	of	of	ADP
admet-442	118	23	transcription	transcription	NOUN
admet-442	118	24	1（stat1）suppressed	1（stat1）suppressed	NUM
admet-442	118	25	the	the	DET
admet-442	118	26	enhanced	enhanced	ADJ
admet-442	118	27	expression	expression	NOUN
admet-442	118	28	of	of	ADP
admet-442	118	29	pd	pd	PROPN
admet-442	118	30	-	-	PROPN
admet-442	118	31	l1	l1	PROPN
admet-442	118	32	induced	induce	VERB
admet-442	118	33	by	by	ADP
admet-442	118	34	ifn	ifn	PROPN
admet-442	118	35	-	-	PUNCT
admet-442	118	36	γ	γ	NOUN
admet-442	118	37	[	[	X
admet-442	118	38	20	20	NUM
admet-442	118	39	]	]	PUNCT
admet-442	118	40	.	.	PUNCT
admet-442	119	1	meanwhile	meanwhile	ADV
admet-442	119	2	,	,	PUNCT
admet-442	119	3	inhibition	inhibition	NOUN
admet-442	119	4	of	of	ADP
admet-442	119	5	the	the	DET
admet-442	119	6	myeloid	myeloid	ADJ
admet-442	119	7	differentiation	differentiation	NOUN
admet-442	119	8	primary	primary	ADJ
admet-442	119	9	response	response	NOUN
admet-442	119	10	gene	gene	NOUN
admet-442	119	11	88（myd88）and	88（myd88）and	PROPN
admet-442	119	12	tnf	tnf	PROPN
admet-442	119	13	receptor	receptor	NOUN
admet-442	119	14	-	-	PUNCT
admet-442	119	15	associated	associate	VERB
admet-442	119	16	factor	factor	NOUN
admet-442	119	17	6（traf6）has	6（traf6）has	PRON
admet-442	119	18	been	be	AUX
admet-442	119	19	reported	report	VERB
admet-442	119	20	to	to	PART
admet-442	119	21	inhibit	inhibit	VERB
admet-442	119	22	pd	pd	PROPN
admet-442	119	23	-	-	PUNCT
admet-442	119	24	l1	l1	PROPN
admet-442	119	25	expression	expression	NOUN
admet-442	119	26	either	either	CCONJ
admet-442	119	27	induced	induce	VERB
admet-442	119	28	by	by	ADP
admet-442	119	29	tlr	tlr	PROPN
admet-442	119	30	ligands	ligand	NOUN
admet-442	119	31	or	or	CCONJ
admet-442	119	32	by	by	ADP
admet-442	119	33	ifn	ifn	PROPN
admet-442	119	34	-	-	PUNCT
admet-442	119	35	γ	γ	NOUN
admet-442	119	36	[	[	X
admet-442	119	37	20	20	NUM
admet-442	119	38	]	]	PUNCT
admet-442	119	39	.	.	PUNCT
admet-442	120	1	in	in	ADP
admet-442	120	2	human	human	ADJ
admet-442	120	3	lung	lung	NOUN
admet-442	120	4	cancer	cancer	NOUN
admet-442	120	5	cells	cell	NOUN
admet-442	120	6	interferon	interferon	ADJ
admet-442	120	7	regulatory	regulatory	ADJ
admet-442	120	8	factor-1	factor-1	PROPN
admet-442	120	9	(	(	PUNCT
admet-442	120	10	irf-1	irf-1	NOUN
admet-442	120	11	)	)	PUNCT
admet-442	120	12	was	be	AUX
admet-442	120	13	necessary	necessary	ADJ
admet-442	120	14	for	for	ADP
admet-442	120	15	induction	induction	NOUN
admet-442	120	16	of	of	ADP
admet-442	120	17	pd	pd	PROPN
admet-442	120	18	-	-	PROPN
admet-442	120	19	l1	l1	PROPN
admet-442	120	20	expression	expression	NOUN
admet-442	120	21	mediated	mediate	VERB
admet-442	120	22	by	by	ADP
admet-442	120	23	ifn	ifn	PROPN
admet-442	120	24	-	-	PUNCT
admet-442	120	25	γ	γ	NOUN
admet-442	120	26	in	in	ADP
admet-442	120	27	stat1	stat1	NOUN
admet-442	120	28	-	-	PUNCT
admet-442	120	29	manner	manner	NOUN
admet-442	120	30	[	[	X
admet-442	120	31	68	68	NUM
admet-442	120	32	]	]	PUNCT
admet-442	120	33	.	.	PUNCT
admet-442	121	1	besides	besides	SCONJ
admet-442	121	2	,	,	PUNCT
admet-442	121	3	a	a	DET
admet-442	121	4	recent	recent	ADJ
admet-442	121	5	study	study	NOUN
admet-442	121	6	also	also	ADV
admet-442	121	7	showed	show	VERB
admet-442	121	8	that	that	SCONJ
admet-442	121	9	enhanced	enhanced	ADJ
admet-442	121	10	expression	expression	NOUN
admet-442	121	11	of	of	ADP
admet-442	121	12	pd	pd	PROPN
admet-442	121	13	-	-	PROPN
admet-442	121	14	l1	l1	PROPN
admet-442	121	15	induced	induce	VERB
admet-442	121	16	by	by	ADP
admet-442	121	17	tlr	tlr	PROPN
admet-442	121	18	also	also	ADV
admet-442	121	19	was	be	AUX
admet-442	121	20	dependent	dependent	ADJ
admet-442	121	21	on	on	ADP
admet-442	121	22	il-	il-	NOUN
admet-442	121	23	,	,	PUNCT
admet-442	121	24	il-10	il-10	NOUN
admet-442	121	25	and	and	CCONJ
admet-442	121	26	stat3	stat3	NOUN
admet-442	121	27	in	in	ADP
admet-442	121	28	apcs	apc	NOUN
admet-442	121	29	[	[	X
admet-442	121	30	69	69	NUM
admet-442	121	31	]	]	PUNCT
admet-442	121	32	.	.	PUNCT
admet-442	122	1	in	in	ADP
admet-442	122	2	addition	addition	NOUN
admet-442	122	3	,	,	PUNCT
admet-442	122	4	ifn	ifn	PROPN
admet-442	122	5	-	-	PUNCT
admet-442	122	6	α	α	PROPN
admet-442	122	7	has	have	AUX
admet-442	122	8	also	also	ADV
admet-442	122	9	been	be	AUX
admet-442	122	10	reported	report	VERB
admet-442	122	11	to	to	PART
admet-442	122	12	induce	induce	VERB
admet-442	122	13	upregulated	upregulated	ADJ
admet-442	122	14	mrna	mrna	NOUN
admet-442	122	15	expression	expression	NOUN
admet-442	122	16	and	and	CCONJ
admet-442	122	17	protein	protein	NOUN
admet-442	122	18	admet	admet	NOUN
admet-442	122	19	&	&	CCONJ
admet-442	122	20	dmpk	dmpk	PROPN
admet-442	122	21	5(3	5(3	NUM
admet-442	122	22	)	)	PUNCT
admet-442	122	23	(	(	PUNCT
admet-442	122	24	2017	2017	NUM
admet-442	122	25	)	)	PUNCT
admet-442	122	26	159	159	NUM
admet-442	122	27	-	-	SYM
admet-442	122	28	172	172	NUM
admet-442	122	29	the	the	DET
admet-442	122	30	function	function	NOUN
admet-442	122	31	and	and	CCONJ
admet-442	122	32	regulation	regulation	NOUN
admet-442	122	33	of	of	ADP
admet-442	122	34	pd	pd	PROPN
admet-442	122	35	-	-	PROPN
admet-442	122	36	l1	l1	PROPN
admet-442	122	37	in	in	ADP
admet-442	122	38	immunotherapy	immunotherapy	NOUN
admet-442	122	39	doi	doi	NOUN
admet-442	122	40	:	:	PUNCT
admet-442	122	41	10.5599	10.5599	NUM
admet-442	122	42	/	/	SYM
admet-442	122	43	admet.5.3.442	admet.5.3.442	NUM
admet-442	122	44	163	163	NUM
admet-442	122	45	expression	expression	NOUN
admet-442	122	46	of	of	ADP
admet-442	122	47	pd	pd	PROPN
admet-442	122	48	-	-	PROPN
admet-442	122	49	l1	l1	PROPN
admet-442	122	50	on	on	ADP
admet-442	122	51	microvascular	microvascular	ADJ
admet-442	122	52	endothelial	endothelial	ADJ
admet-442	122	53	cells	cell	NOUN
admet-442	122	54	(	(	PUNCT
admet-442	122	55	ecs	ecs	PROPN
admet-442	122	56	)	)	PUNCT
admet-442	123	1	[	[	X
admet-442	123	2	70	70	NUM
admet-442	123	3	]	]	PUNCT
admet-442	123	4	.	.	PUNCT
admet-442	124	1	moreover	moreover	ADV
admet-442	124	2	the	the	DET
admet-442	124	3	enhanced	enhanced	ADJ
admet-442	124	4	expression	expression	NOUN
admet-442	124	5	of	of	ADP
admet-442	124	6	pd	pd	PROPN
admet-442	124	7	-	-	PROPN
admet-442	124	8	l1	l1	PROPN
admet-442	124	9	protein	protein	NOUN
admet-442	124	10	and	and	CCONJ
admet-442	124	11	mrna	mrna	PROPN
admet-442	124	12	was	be	AUX
admet-442	124	13	induced	induce	VERB
admet-442	124	14	by	by	ADP
admet-442	124	15	ifn	ifn	PROPN
admet-442	124	16	-	-	PUNCT
admet-442	124	17	β	β	NOUN
admet-442	124	18	on	on	ADP
admet-442	124	19	monocytes	monocyte	NOUN
admet-442	124	20	and	and	CCONJ
admet-442	124	21	mature	mature	VERB
admet-442	124	22	dendritic	dendritic	ADJ
admet-442	124	23	cells	cell	NOUN
admet-442	124	24	of	of	ADP
admet-442	124	25	healthy	healthy	ADJ
admet-442	124	26	donors	donor	NOUN
admet-442	124	27	and	and	CCONJ
admet-442	124	28	multiple	multiple	ADJ
admet-442	124	29	sclerosis	sclerosis	NOUN
admet-442	124	30	(	(	PUNCT
admet-442	124	31	ms	ms	NOUN
admet-442	124	32	)	)	PUNCT
admet-442	124	33	patients	patient	NOUN
admet-442	124	34	[	[	X
admet-442	124	35	71	71	NUM
admet-442	124	36	]	]	PUNCT
admet-442	124	37	.	.	PUNCT
admet-442	125	1	figure	figure	NOUN
admet-442	125	2	1	1	NUM
admet-442	125	3	.	.	PUNCT
admet-442	125	4	schematic	schematic	ADJ
admet-442	125	5	diagram	diagram	NOUN
admet-442	125	6	and	and	CCONJ
admet-442	125	7	structure	structure	NOUN
admet-442	125	8	of	of	ADP
admet-442	125	9	pd	pd	PROPN
admet-442	125	10	-	-	PROPN
admet-442	125	11	l1	l1	PROPN
admet-442	125	12	protein	protein	NOUN
admet-442	125	13	.	.	PUNCT
admet-442	126	1	a.	a.	PROPN
admet-442	126	2	schematic	schematic	ADJ
admet-442	126	3	diagram	diagram	NOUN
admet-442	126	4	of	of	ADP
admet-442	126	5	pd	pd	PROPN
admet-442	126	6	-	-	PROPN
admet-442	126	7	l1	l1	PROPN
admet-442	126	8	protein	protein	NOUN
admet-442	126	9	.	.	PUNCT
admet-442	127	1	sp	sp	NOUN
admet-442	127	2	:	:	PUNCT
admet-442	127	3	signal	signal	NOUN
admet-442	127	4	peptide	peptide	NOUN
admet-442	127	5	;	;	PUNCT
admet-442	127	6	ecd	ecd	PROPN
admet-442	127	7	:	:	PUNCT
admet-442	127	8	extracellular	extracellular	ADJ
admet-442	127	9	domain	domain	NOUN
admet-442	127	10	;	;	PUNCT
admet-442	127	11	tm	tm	NOUN
admet-442	127	12	:	:	PUNCT
admet-442	127	13	transmembrane	transmembrane	ADJ
admet-442	127	14	domain	domain	NOUN
admet-442	127	15	;	;	PUNCT
admet-442	127	16	icd	icd	NOUN
admet-442	127	17	;	;	PUNCT
admet-442	127	18	intracellular	intracellular	ADJ
admet-442	127	19	domain	domain	NOUN
admet-442	127	20	.	.	PUNCT
admet-442	128	1	b.	b.	PROPN
admet-442	128	2	structure	structure	NOUN
admet-442	128	3	of	of	ADP
admet-442	128	4	pd	pd	PROPN
admet-442	128	5	-	-	PROPN
admet-442	128	6	l1	l1	PROPN
admet-442	128	7	protein	protein	NOUN
admet-442	128	8	.	.	PUNCT
admet-442	129	1	this	this	DET
admet-442	129	2	structure	structure	NOUN
admet-442	129	3	shows	show	VERB
admet-442	129	4	two	two	NUM
admet-442	129	5	main	main	ADJ
admet-442	129	6	anti	anti	ADJ
admet-442	129	7	-	-	ADJ
admet-442	129	8	parallel	parallel	ADJ
admet-442	129	9	β	β	X
admet-442	129	10	sandwich	sandwich	NOUN
admet-442	129	11	immunoglobulin	immunoglobulin	NOUN
admet-442	129	12	superfamily	superfamily	ADV
admet-442	129	13	(	(	PUNCT
admet-442	129	14	ig	ig	PROPN
admet-442	129	15	sf	sf	PROPN
admet-442	129	16	)	)	PUNCT
admet-442	129	17	domains	domain	NOUN
admet-442	129	18	of	of	ADP
admet-442	129	19	pd	pd	PROPN
admet-442	129	20	=	=	PROPN
admet-442	129	21	l1	l1	PROPN
admet-442	129	22	protein	protein	NOUN
admet-442	129	23	.	.	PUNCT
admet-442	130	1	inflammatory	inflammatory	ADJ
admet-442	130	2	macrophages	macrophage	NOUN
admet-442	130	3	upregulate	upregulate	VERB
admet-442	130	4	expression	expression	NOUN
admet-442	130	5	of	of	ADP
admet-442	130	6	pd	pd	PROPN
admet-442	130	7	-	-	PROPN
admet-442	130	8	l1	l1	PROPN
admet-442	130	9	,	,	PUNCT
admet-442	130	10	which	which	PRON
admet-442	130	11	was	be	AUX
admet-442	130	12	also	also	ADV
admet-442	130	13	induced	induce	VERB
admet-442	130	14	by	by	ADP
admet-442	130	15	lipopolysaccharide	lipopolysaccharide	ADJ
admet-442	130	16	(	(	PUNCT
admet-442	130	17	lps	lps	PROPN
admet-442	130	18	)	)	PUNCT
admet-442	131	1	[	[	X
admet-442	131	2	72	72	NUM
admet-442	131	3	]	]	PUNCT
admet-442	131	4	.	.	PUNCT
admet-442	132	1	enhanced	enhance	VERB
admet-442	132	2	expression	expression	NOUN
admet-442	132	3	of	of	ADP
admet-442	132	4	pd	pd	PROPN
admet-442	132	5	-	-	PROPN
admet-442	132	6	l1	l1	PROPN
admet-442	132	7	was	be	AUX
admet-442	132	8	present	present	ADJ
admet-442	132	9	on	on	ADP
admet-442	132	10	immature	immature	ADJ
admet-442	132	11	dendritic	dendritic	ADJ
admet-442	132	12	cells	cell	NOUN
admet-442	132	13	(	(	PUNCT
admet-442	132	14	idcs	idcs	ADJ
admet-442	132	15	)	)	PUNCT
admet-442	132	16	after	after	ADP
admet-442	132	17	being	be	AUX
admet-442	132	18	treated	treat	VERB
admet-442	132	19	with	with	ADP
admet-442	132	20	granulocyte	granulocyte	ADJ
admet-442	132	21	-	-	PUNCT
admet-442	132	22	macrophage	macrophage	ADJ
admet-442	132	23	colony	colony	NOUN
admet-442	132	24	-	-	PUNCT
admet-442	132	25	stimulating	stimulate	VERB
admet-442	132	26	factor	factor	NOUN
admet-442	132	27	(	(	PUNCT
admet-442	132	28	gm	gm	PROPN
admet-442	132	29	-	-	PUNCT
admet-442	132	30	csf	csf	NOUN
admet-442	132	31	)	)	PUNCT
admet-442	133	1	[	[	X
admet-442	133	2	73	73	NUM
admet-442	133	3	]	]	PUNCT
admet-442	133	4	.	.	PUNCT
admet-442	134	1	ou	ou	PROPN
admet-442	134	2	et	et	PROPN
admet-442	134	3	al	al	PROPN
admet-442	134	4	.	.	PROPN
admet-442	134	5	reported	report	VERB
admet-442	134	6	that	that	SCONJ
admet-442	134	7	in	in	ADP
admet-442	134	8	sle	sle	PROPN
admet-442	134	9	monocytes	monocyte	VERB
admet-442	134	10	opposing	oppose	VERB
admet-442	134	11	actions	action	NOUN
admet-442	134	12	of	of	ADP
admet-442	134	13	tnf	tnf	PROPN
admet-442	134	14	-	-	PUNCT
admet-442	134	15	α	α	PROPN
admet-442	134	16	and	and	CCONJ
admet-442	134	17	transforming	transform	VERB
admet-442	134	18	growth	growth	NOUN
admet-442	134	19	factor	factor	NOUN
admet-442	134	20	(	(	PUNCT
admet-442	134	21	tgf)-β	tgf)-β	PRON
admet-442	134	22	regulated	regulate	VERB
admet-442	134	23	the	the	DET
admet-442	134	24	expression	expression	NOUN
admet-442	134	25	of	of	ADP
admet-442	134	26	pd	pd	PROPN
admet-442	134	27	-	-	PROPN
admet-442	134	28	l1	l1	PROPN
admet-442	135	1	[	[	X
admet-442	135	2	74	74	NUM
admet-442	135	3	]	]	PUNCT
admet-442	135	4	.	.	PUNCT
admet-442	136	1	pd	pd	PROPN
admet-442	136	2	-	-	PUNCT
admet-442	136	3	l1	l1	PROPN
admet-442	136	4	expression	expression	NOUN
admet-442	136	5	could	could	AUX
admet-442	136	6	be	be	AUX
admet-442	136	7	revived	revive	VERB
admet-442	136	8	by	by	ADP
admet-442	136	9	exogenous	exogenous	ADJ
admet-442	136	10	tnf	tnf	PROPN
admet-442	136	11	-	-	PUNCT
admet-442	136	12	α	α	NOUN
admet-442	136	13	on	on	ADP
admet-442	136	14	lupus	lupus	NOUN
admet-442	136	15	monocytes	monocyte	VERB
admet-442	136	16	[	[	X
admet-442	136	17	74	74	NUM
admet-442	136	18	]	]	PUNCT
admet-442	136	19	.	.	PUNCT
admet-442	137	1	tgf	tgf	PROPN
admet-442	137	2	-	-	PUNCT
admet-442	137	3	β	β	PROPN
admet-442	137	4	has	have	AUX
admet-442	137	5	shown	show	VERB
admet-442	137	6	to	to	PART
admet-442	137	7	inhibit	inhibit	VERB
admet-442	137	8	pd	pd	PROPN
admet-442	137	9	-	-	PUNCT
admet-442	137	10	l1	l1	PROPN
admet-442	137	11	expression	expression	NOUN
admet-442	137	12	on	on	ADP
admet-442	137	13	monocytes	monocyte	NOUN
admet-442	137	14	[	[	X
admet-442	137	15	74	74	NUM
admet-442	137	16	]	]	PUNCT
admet-442	137	17	.	.	PUNCT
admet-442	138	1	induction	induction	NOUN
admet-442	138	2	of	of	ADP
admet-442	138	3	pd	pd	PROPN
admet-442	138	4	-	-	PUNCT
admet-442	138	5	l1	l1	PROPN
admet-442	138	6	expression	expression	NOUN
admet-442	138	7	is	be	AUX
admet-442	138	8	also	also	ADV
admet-442	138	9	associated	associate	VERB
admet-442	138	10	with	with	ADP
admet-442	138	11	janus	janus	PROPN
admet-442	138	12	kinase	kinase	PROPN
admet-442	138	13	(	(	PUNCT
admet-442	138	14	jak)/stat	jak)/stat	X
admet-442	138	15	signaling	signal	VERB
admet-442	138	16	and	and	CCONJ
admet-442	138	17	activator	activator	NOUN
admet-442	138	18	protein	protein	NOUN
admet-442	138	19	1	1	NUM
admet-442	138	20	(	(	PUNCT
admet-442	138	21	ap1	ap1	NOUN
admet-442	138	22	)	)	PUNCT
admet-442	138	23	activity	activity	NOUN
admet-442	138	24	[	[	X
admet-442	138	25	75	75	NUM
admet-442	138	26	]	]	PUNCT
admet-442	138	27	.	.	PUNCT
admet-442	139	1	michael	michael	PROPN
admet-442	139	2	et	et	PROPN
admet-442	139	3	al	al	PROPN
admet-442	139	4	.	.	PROPN
admet-442	139	5	showed	show	VERB
admet-442	139	6	that	that	SCONJ
admet-442	139	7	in	in	ADP
admet-442	139	8	classical	classical	ADJ
admet-442	139	9	hodgkin	hodgkin	PROPN
admet-442	139	10	lymphoma	lymphoma	NOUN
admet-442	139	11	reed	reed	NOUN
admet-442	139	12	–	–	PUNCT
admet-442	139	13	sternberg	sternberg	PROPN
admet-442	139	14	cells	cell	NOUN
admet-442	139	15	constitutive	constitutive	ADJ
admet-442	139	16	activation	activation	NOUN
admet-442	139	17	of	of	ADP
admet-442	139	18	ap-1	ap-1	ADV
admet-442	139	19	resulted	result	VERB
admet-442	139	20	in	in	ADP
admet-442	139	21	the	the	DET
admet-442	139	22	binding	binding	NOUN
admet-442	139	23	of	of	ADP
admet-442	139	24	ap-1	ap-1	ADP
admet-442	139	25	components	component	NOUN
admet-442	139	26	to	to	PART
admet-442	139	27	enhancer	enhancer	VERB
admet-442	139	28	of	of	ADP
admet-442	139	29	cd274	cd274	PROPN
admet-442	139	30	gene	gene	NOUN
admet-442	139	31	,	,	PUNCT
admet-442	139	32	which	which	PRON
admet-442	139	33	enhanced	enhance	VERB
admet-442	139	34	the	the	DET
admet-442	139	35	activity	activity	NOUN
admet-442	139	36	of	of	ADP
admet-442	139	37	pd	pd	PROPN
admet-442	139	38	-	-	PROPN
admet-442	139	39	l1	l1	PROPN
admet-442	139	40	promoter	promoter	NOUN
admet-442	140	1	[	[	X
admet-442	140	2	75	75	NUM
admet-442	140	3	]	]	PUNCT
admet-442	140	4	.	.	PUNCT
admet-442	141	1	the	the	DET
admet-442	141	2	induction	induction	NOUN
admet-442	141	3	of	of	ADP
admet-442	141	4	pd	pd	PROPN
admet-442	141	5	-	-	PROPN
admet-442	141	6	l1	l1	PROPN
admet-442	141	7	expression	expression	NOUN
admet-442	141	8	by	by	ADP
admet-442	141	9	jak2	jak2	PROPN
admet-442	141	10	was	be	AUX
admet-442	141	11	also	also	ADV
admet-442	141	12	observed	observe	VERB
admet-442	141	13	in	in	ADP
admet-442	141	14	this	this	DET
admet-442	141	15	study	study	NOUN
admet-442	141	16	,	,	PUNCT
admet-442	141	17	which	which	PRON
admet-442	141	18	was	be	AUX
admet-442	141	19	associated	associate	VERB
admet-442	141	20	with	with	ADP
admet-442	141	21	jak	jak	PROPN
admet-442	141	22	/	/	SYM
admet-442	141	23	stat	stat	NOUN
admet-442	141	24	-	-	PUNCT
admet-442	141	25	dependent	dependent	ADJ
admet-442	141	26	promoter	promoter	NOUN
admet-442	141	27	in	in	ADP
admet-442	141	28	cd274	cd274	PROPN
admet-442	141	29	gene	gene	NOUN
admet-442	141	30	[	[	X
admet-442	141	31	75	75	NUM
admet-442	141	32	]	]	PUNCT
admet-442	141	33	.	.	PUNCT
admet-442	142	1	besides	besides	SCONJ
admet-442	142	2	,	,	PUNCT
admet-442	142	3	the	the	DET
admet-442	142	4	increase	increase	NOUN
admet-442	142	5	of	of	ADP
admet-442	142	6	pdl1	pdl1	NOUN
admet-442	142	7	expression	expression	NOUN
admet-442	142	8	protein	protein	NOUN
admet-442	142	9	was	be	AUX
admet-442	142	10	induced	induce	VERB
admet-442	142	11	by	by	ADP
admet-442	142	12	inhibition	inhibition	NOUN
admet-442	142	13	of	of	ADP
admet-442	142	14	phosphatase	phosphatase	NOUN
admet-442	142	15	and	and	CCONJ
admet-442	142	16	tensin	tensin	PROPN
admet-442	142	17	homolog	homolog	PROPN
admet-442	142	18	(	(	PUNCT
admet-442	142	19	pten	pten	NOUN
admet-442	142	20	)	)	PUNCT
admet-442	142	21	in	in	ADP
admet-442	142	22	glioma	glioma	NOUN
admet-442	142	23	cancer	cancer	NOUN
admet-442	142	24	and	and	CCONJ
admet-442	142	25	colorectal	colorectal	ADJ
admet-442	142	26	cancer	cancer	NOUN
admet-442	142	27	[	[	X
admet-442	142	28	22	22	NUM
admet-442	142	29	]	]	PUNCT
admet-442	142	30	.	.	PUNCT
admet-442	143	1	recent	recent	ADJ
admet-442	143	2	studies	study	NOUN
admet-442	143	3	reported	report	VERB
admet-442	143	4	that	that	SCONJ
admet-442	143	5	pd	pd	PROPN
admet-442	143	6	-	-	PUNCT
admet-442	143	7	l1	l1	PROPN
admet-442	143	8	expression	expression	NOUN
admet-442	143	9	was	be	AUX
admet-442	143	10	inhibited	inhibit	VERB
admet-442	143	11	by	by	ADP
admet-442	143	12	p53	p53	NOUN
admet-442	143	13	through	through	ADP
admet-442	143	14	regulating	regulate	VERB
admet-442	143	15	mir-34a	mir-34a	NOUN
admet-442	143	16	and	and	CCONJ
admet-442	143	17	mir-200	mir-200	NOUN
admet-442	144	1	[	[	X
admet-442	144	2	76	76	NUM
admet-442	144	3	,	,	PUNCT
admet-442	144	4	77	77	NUM
admet-442	144	5	]	]	PUNCT
admet-442	144	6	.	.	PUNCT
admet-442	145	1	the	the	DET
admet-442	145	2	il	il	PROPN
admet-442	145	3	family	family	PROPN
admet-442	145	4	also	also	ADV
admet-442	145	5	was	be	AUX
admet-442	145	6	indicated	indicate	VERB
admet-442	145	7	to	to	PART
admet-442	145	8	be	be	AUX
admet-442	145	9	important	important	ADJ
admet-442	145	10	for	for	ADP
admet-442	145	11	induction	induction	NOUN
admet-442	145	12	of	of	ADP
admet-442	145	13	pd	pd	PROPN
admet-442	145	14	-	-	PROPN
admet-442	145	15	l1	l1	PROPN
admet-442	145	16	expression	expression	NOUN
admet-442	145	17	.	.	PUNCT
admet-442	146	1	for	for	ADP
admet-442	146	2	instance	instance	NOUN
admet-442	146	3	,	,	PUNCT
admet-442	146	4	il-27	il-27	PUNCT
admet-442	146	5	enhanced	enhance	VERB
admet-442	146	6	the	the	DET
admet-442	146	7	expression	expression	NOUN
admet-442	146	8	of	of	ADP
admet-442	146	9	cd274	cd274	PROPN
admet-442	146	10	gene	gene	NOUN
admet-442	146	11	which	which	PRON
admet-442	146	12	is	be	AUX
admet-442	146	13	dependent	dependent	ADJ
admet-442	146	14	on	on	ADP
admet-442	146	15	stat1	stat1	PROPN
admet-442	146	16	on	on	ADP
admet-442	146	17	naïve	naïve	ADJ
admet-442	146	18	t	t	NOUN
admet-442	146	19	cells	cell	NOUN
admet-442	146	20	[	[	X
admet-442	146	21	78	78	NUM
admet-442	146	22	]	]	PUNCT
admet-442	146	23	.	.	PUNCT
admet-442	147	1	further	further	ADJ
admet-442	147	2	study	study	PROPN
admet-442	147	3	guo	guo	PROPN
admet-442	147	4	,	,	PUNCT
admet-442	147	5	lin	lin	PROPN
admet-442	147	6	and	and	CCONJ
admet-442	147	7	kwok	kwok	PROPN
admet-442	147	8	admet	admet	PROPN
admet-442	147	9	&	&	CCONJ
admet-442	147	10	dmpk	dmpk	PROPN
admet-442	147	11	5(3	5(3	NUM
admet-442	147	12	)	)	PUNCT
admet-442	147	13	(	(	PUNCT
admet-442	147	14	2017	2017	NUM
admet-442	147	15	)	)	PUNCT
admet-442	147	16	159	159	NUM
admet-442	147	17	-	-	SYM
admet-442	147	18	172	172	NUM
admet-442	147	19	164	164	NUM
admet-442	147	20	showed	show	VERB
admet-442	147	21	that	that	SCONJ
admet-442	147	22	pd	pd	PROPN
admet-442	147	23	-	-	PUNCT
admet-442	147	24	l1	l1	PROPN
admet-442	147	25	expression	expression	NOUN
admet-442	147	26	was	be	AUX
admet-442	147	27	increased	increase	VERB
admet-442	147	28	which	which	PRON
admet-442	147	29	was	be	AUX
admet-442	147	30	mediated	mediate	VERB
admet-442	147	31	by	by	ADP
admet-442	147	32	il-4	il-4	NOUN
admet-442	147	33	in	in	ADP
admet-442	147	34	nuclear	nuclear	ADJ
admet-442	147	35	factor	factor	NOUN
admet-442	147	36	-	-	PUNCT
admet-442	147	37	kappa	kappa	PROPN
admet-442	147	38	b	b	PROPN
admet-442	147	39	(	(	PUNCT
admet-442	147	40	nf	nf	NOUN
admet-442	147	41	-	-	PUNCT
admet-442	147	42	κb	κb	NOUN
admet-442	147	43	)	)	PUNCT
admet-442	147	44	p50–/	p50–/	PROPN
admet-442	147	45	–	–	PUNCT
admet-442	147	46	p65+/	p65+/	NOUN
admet-442	147	47	–	–	PUNCT
admet-442	147	48	dendritic	dendritic	ADJ
admet-442	147	49	cell	cell	NOUN
admet-442	147	50	(	(	PUNCT
admet-442	147	51	dc	dc	PROPN
admet-442	147	52	)	)	PUNCT
admet-442	148	1	[	[	X
admet-442	148	2	38	38	NUM
admet-442	148	3	]	]	PUNCT
admet-442	148	4	.	.	PUNCT
admet-442	149	1	the	the	DET
admet-442	149	2	pd	pd	PROPN
admet-442	149	3	-	-	PUNCT
admet-442	149	4	l1	l1	PROPN
admet-442	149	5	expression	expression	NOUN
admet-442	149	6	was	be	AUX
admet-442	149	7	not	not	PART
admet-442	149	8	only	only	ADV
admet-442	149	9	induced	induce	VERB
admet-442	149	10	by	by	ADP
admet-442	149	11	multiple	multiple	ADJ
admet-442	149	12	pro	pro	ADJ
admet-442	149	13	-	-	ADJ
admet-442	149	14	inflammatory	inflammatory	ADJ
admet-442	149	15	molecules	molecule	NOUN
admet-442	149	16	,	,	PUNCT
admet-442	149	17	but	but	CCONJ
admet-442	149	18	also	also	ADV
admet-442	149	19	influenced	influence	VERB
admet-442	149	20	by	by	ADP
admet-442	149	21	t	t	NOUN
admet-442	149	22	cells	cell	NOUN
admet-442	149	23	.	.	PUNCT
admet-442	150	1	for	for	ADP
admet-442	150	2	example	example	NOUN
admet-442	150	3	,	,	PUNCT
admet-442	150	4	enhanced	enhanced	ADJ
admet-442	150	5	expression	expression	NOUN
admet-442	150	6	of	of	ADP
admet-442	150	7	pd	pd	PROPN
admet-442	150	8	-	-	PROPN
admet-442	150	9	l1	l1	PROPN
admet-442	150	10	induced	induce	VERB
admet-442	150	11	by	by	ADP
admet-442	150	12	type	type	NOUN
admet-442	150	13	1	1	NUM
admet-442	150	14	t	t	NOUN
admet-442	150	15	helper	helper	NOUN
admet-442	150	16	(	(	PUNCT
admet-442	150	17	th1	th1	NOUN
admet-442	150	18	)	)	PUNCT
admet-442	150	19	cells	cell	NOUN
admet-442	150	20	was	be	AUX
admet-442	150	21	also	also	ADV
admet-442	150	22	found	find	VERB
admet-442	150	23	on	on	ADP
admet-442	150	24	different	different	ADJ
admet-442	150	25	macrophages	macrophage	NOUN
admet-442	150	26	[	[	X
admet-442	150	27	72	72	NUM
admet-442	150	28	]	]	PUNCT
admet-442	150	29	.	.	PUNCT
admet-442	151	1	activation	activation	NOUN
admet-442	151	2	of	of	ADP
admet-442	151	3	human	human	ADJ
admet-442	151	4	t	t	PROPN
admet-442	151	5	cells	cell	NOUN
admet-442	151	6	by	by	ADP
admet-442	151	7	anti	anti	ADJ
admet-442	151	8	-	-	ADJ
admet-442	151	9	cd3	cd3	ADJ
admet-442	151	10	and	and	CCONJ
admet-442	151	11	anti	anti	ADJ
admet-442	151	12	-	-	PROPN
admet-442	151	13	cd28	cd28	PROPN
admet-442	151	14	may	may	AUX
admet-442	151	15	lead	lead	VERB
admet-442	151	16	to	to	ADP
admet-442	151	17	increased	increase	VERB
admet-442	151	18	expression	expression	NOUN
admet-442	151	19	of	of	ADP
admet-442	151	20	pd	pd	PROPN
admet-442	151	21	-	-	PROPN
admet-442	151	22	l1	l1	PROPN
admet-442	151	23	mrna	mrna	PROPN
admet-442	152	1	[	[	X
admet-442	152	2	79	79	NUM
admet-442	152	3	]	]	PUNCT
admet-442	152	4	.	.	PUNCT
admet-442	153	1	figure	figure	NOUN
admet-442	153	2	2	2	NUM
admet-442	153	3	.	.	X
admet-442	153	4	pd	pd	PROPN
admet-442	153	5	-	-	PUNCT
admet-442	153	6	l1	l1	PROPN
admet-442	153	7	expression	expression	NOUN
admet-442	153	8	is	be	AUX
admet-442	153	9	regulated	regulate	VERB
admet-442	153	10	by	by	ADP
admet-442	153	11	several	several	ADJ
admet-442	153	12	cytokines	cytokine	NOUN
admet-442	153	13	.	.	PUNCT
admet-442	154	1	a.	a.	NOUN
admet-442	154	2	upregulation	upregulation	NOUN
admet-442	154	3	of	of	ADP
admet-442	154	4	pd	pd	PROPN
admet-442	154	5	-	-	PROPN
admet-442	154	6	l1	l1	PROPN
admet-442	154	7	is	be	AUX
admet-442	154	8	induced	induce	VERB
admet-442	154	9	by	by	ADP
admet-442	154	10	various	various	ADJ
admet-442	154	11	pro	pro	ADJ
admet-442	154	12	-	-	ADJ
admet-442	154	13	inflammatory	inflammatory	ADJ
admet-442	154	14	molecules	molecule	NOUN
admet-442	154	15	.	.	PUNCT
admet-442	155	1	pd	pd	PROPN
admet-442	155	2	-	-	PROPN
admet-442	155	3	l1	l1	PROPN
admet-442	155	4	could	could	AUX
admet-442	155	5	be	be	AUX
admet-442	155	6	induced	induce	VERB
admet-442	155	7	by	by	ADP
admet-442	155	8	ifn	ifn	PROPN
admet-442	155	9	-	-	PUNCT
admet-442	155	10	γ	γ	NOUN
admet-442	155	11	and	and	CCONJ
admet-442	155	12	tlr	tlr	PROPN
admet-442	155	13	ligands	ligand	NOUN
admet-442	155	14	via	via	ADP
admet-442	155	15	regulation	regulation	NOUN
admet-442	155	16	of	of	ADP
admet-442	155	17	downstream	downstream	ADJ
admet-442	155	18	adaptor	adaptor	NOUN
admet-442	155	19	proteins	protein	NOUN
admet-442	155	20	of	of	ADP
admet-442	155	21	the	the	DET
admet-442	155	22	tlr	tlr	PROPN
admet-442	155	23	signaling	signal	VERB
admet-442	155	24	pathway	pathway	NOUN
admet-442	155	25	.	.	PUNCT
admet-442	156	1	ifn	ifn	PROPN
admet-442	156	2	-	-	PUNCT
admet-442	156	3	γ	γ	PROPN
admet-442	156	4	also	also	ADV
admet-442	156	5	induced	induce	VERB
admet-442	156	6	pd	pd	ADJ
admet-442	156	7	-	-	PUNCT
admet-442	156	8	l1	l1	PROPN
admet-442	156	9	expression	expression	NOUN
admet-442	156	10	through	through	ADP
admet-442	156	11	jak	jak	PROPN
admet-442	156	12	-	-	PUNCT
admet-442	156	13	stat1	stat1	PROPN
admet-442	156	14	signaling	signal	VERB
admet-442	156	15	pathway	pathway	NOUN
admet-442	156	16	.	.	PUNCT
admet-442	157	1	except	except	SCONJ
admet-442	157	2	that	that	PRON
admet-442	157	3	,	,	PUNCT
admet-442	157	4	some	some	DET
admet-442	157	5	other	other	ADJ
admet-442	157	6	cytokines	cytokine	NOUN
admet-442	157	7	,	,	PUNCT
admet-442	157	8	like	like	ADP
admet-442	157	9	gm	gm	PROPN
admet-442	157	10	-	-	PUNCT
admet-442	157	11	csf	csf	PROPN
admet-442	157	12	,	,	PUNCT
admet-442	157	13	tnf	tnf	PROPN
admet-442	157	14	-	-	PUNCT
admet-442	157	15	alpha	alpha	PROPN
admet-442	157	16	,	,	PUNCT
admet-442	157	17	il	il	PROPN
admet-442	157	18	,	,	PUNCT
admet-442	157	19	can	can	AUX
admet-442	157	20	increase	increase	VERB
admet-442	157	21	pd	pd	ADJ
admet-442	157	22	-	-	PUNCT
admet-442	157	23	l1	l1	PROPN
admet-442	157	24	expression	expression	NOUN
admet-442	157	25	.	.	PUNCT
admet-442	158	1	b.	b.	NOUN
admet-442	158	2	inhibition	inhibition	NOUN
admet-442	158	3	of	of	ADP
admet-442	158	4	pd	pd	PROPN
admet-442	158	5	-	-	PUNCT
admet-442	158	6	l1	l1	PROPN
admet-442	158	7	expression	expression	NOUN
admet-442	158	8	is	be	AUX
admet-442	158	9	mediated	mediate	VERB
admet-442	158	10	by	by	ADP
admet-442	158	11	p53	p53	NOUN
admet-442	158	12	,	,	PUNCT
admet-442	158	13	pten	pten	NOUN
admet-442	158	14	and	and	CCONJ
admet-442	158	15	tgf	tgf	PROPN
admet-442	158	16	-	-	PUNCT
admet-442	158	17	β	β	PROPN
admet-442	158	18	.	.	PUNCT
admet-442	159	1	pd	pd	PROPN
admet-442	159	2	-	-	PUNCT
admet-442	159	3	l1	l1	PROPN
admet-442	159	4	/	/	SYM
admet-442	159	5	pd-1	pd-1	NOUN
admet-442	159	6	signaling	signal	VERB
admet-442	159	7	pathway	pathway	NOUN
admet-442	159	8	several	several	ADJ
admet-442	159	9	studies	study	NOUN
admet-442	159	10	reported	report	VERB
admet-442	159	11	that	that	SCONJ
admet-442	159	12	pd	pd	PROPN
admet-442	159	13	-	-	PROPN
admet-442	159	14	l1	l1	PROPN
admet-442	159	15	can	can	AUX
admet-442	159	16	interact	interact	VERB
admet-442	159	17	with	with	ADP
admet-442	159	18	pd-1	pd-1	ADV
admet-442	159	19	,	,	PUNCT
admet-442	159	20	and	and	CCONJ
admet-442	159	21	this	this	DET
admet-442	159	22	interaction	interaction	NOUN
admet-442	159	23	delivered	deliver	VERB
admet-442	159	24	an	an	DET
admet-442	159	25	inhibitory	inhibitory	ADJ
admet-442	159	26	signals	signal	NOUN
admet-442	159	27	to	to	PART
admet-442	159	28	regulate	regulate	VERB
admet-442	159	29	immune	immune	ADJ
admet-442	159	30	tolerance	tolerance	NOUN
admet-442	159	31	and	and	CCONJ
admet-442	159	32	immunopathology	immunopathology	NOUN
admet-442	159	33	[	[	X
admet-442	159	34	80	80	NUM
admet-442	159	35	]	]	PUNCT
admet-442	159	36	.	.	PUNCT
admet-442	160	1	most	most	ADV
admet-442	160	2	importantly	importantly	ADV
admet-442	160	3	,	,	PUNCT
admet-442	160	4	pd	pd	PROPN
admet-442	160	5	-	-	PUNCT
admet-442	160	6	l1	l1	PROPN
admet-442	160	7	/	/	SYM
admet-442	160	8	pd-1	pd-1	VERB
admet-442	160	9	signaling	signal	VERB
admet-442	160	10	may	may	AUX
admet-442	160	11	exert	exert	VERB
admet-442	160	12	its	its	PRON
admet-442	160	13	inhibitory	inhibitory	ADJ
admet-442	160	14	effect	effect	NOUN
admet-442	160	15	on	on	ADP
admet-442	160	16	immune	immune	ADJ
admet-442	160	17	response	response	NOUN
admet-442	160	18	through	through	ADP
admet-442	160	19	signaling	signal	VERB
admet-442	160	20	pathway	pathway	NOUN
admet-442	160	21	mediated	mediate	VERB
admet-442	160	22	by	by	ADP
admet-442	160	23	various	various	ADJ
admet-442	160	24	types	type	NOUN
admet-442	160	25	of	of	ADP
admet-442	160	26	cytokines	cytokine	NOUN
admet-442	160	27	,	,	PUNCT
admet-442	160	28	such	such	ADJ
admet-442	160	29	as	as	ADP
admet-442	160	30	shp-1	shp-1	NOUN
admet-442	160	31	,	,	PUNCT
admet-442	160	32	tcr	tcr	PROPN
admet-442	160	33	,	,	PUNCT
admet-442	160	34	phosphoinositide	phosphoinositide	NOUN
admet-442	160	35	3	3	NUM
admet-442	160	36	-	-	PUNCT
admet-442	160	37	kinase	kinase	NOUN
admet-442	160	38	(	(	PUNCT
admet-442	160	39	pi3k	pi3k	PROPN
admet-442	160	40	)	)	PUNCT
admet-442	160	41	.	.	PUNCT
admet-442	161	1	figure	figure	NOUN
admet-442	161	2	3	3	NUM
admet-442	161	3	shows	show	VERB
admet-442	161	4	pd	pd	PROPN
admet-442	161	5	-	-	PROPN
admet-442	161	6	l1	l1	PROPN
admet-442	161	7	/	/	SYM
admet-442	161	8	pd-1	pd-1	VERB
admet-442	161	9	signaling	signal	VERB
admet-442	161	10	pathway	pathway	NOUN
admet-442	161	11	regulating	regulate	VERB
admet-442	161	12	t	t	PROPN
admet-442	161	13	cell	cell	NOUN
admet-442	161	14	survival	survival	NOUN
admet-442	161	15	.	.	PUNCT
admet-442	162	1	the	the	DET
admet-442	162	2	effector	effector	NOUN
admet-442	162	3	t	t	PROPN
admet-442	162	4	cells	cell	NOUN
admet-442	162	5	interaction	interaction	NOUN
admet-442	162	6	of	of	ADP
admet-442	162	7	pd	pd	PROPN
admet-442	162	8	-	-	PROPN
admet-442	162	9	l1	l1	PROPN
admet-442	162	10	and	and	CCONJ
admet-442	162	11	pd-1	pd-1	ADV
admet-442	162	12	blocked	block	VERB
admet-442	162	13	tcr	tcr	PROPN
admet-442	162	14	signal	signal	PROPN
admet-442	162	15	transduction	transduction	NOUN
admet-442	162	16	,	,	PUNCT
admet-442	162	17	leading	lead	VERB
admet-442	162	18	to	to	ADP
admet-442	162	19	inhibition	inhibition	NOUN
admet-442	162	20	of	of	ADP
admet-442	162	21	t	t	NOUN
admet-442	162	22	cell	cell	NOUN
admet-442	162	23	cytotoxic	cytotoxic	ADJ
admet-442	162	24	activity	activity	NOUN
admet-442	162	25	[	[	X
admet-442	162	26	81	81	NUM
admet-442	162	27	]	]	PUNCT
admet-442	162	28	.	.	PUNCT
admet-442	163	1	the	the	DET
admet-442	163	2	src	src	NOUN
admet-442	163	3	homology	homology	NOUN
admet-442	163	4	region	region	NOUN
admet-442	163	5	2	2	NUM
admet-442	163	6	domain	domain	NOUN
admet-442	163	7	containing	contain	VERB
admet-442	163	8	phosphatase-1	phosphatase-1	NOUN
admet-442	163	9	(	(	PUNCT
admet-442	163	10	shp1	shp1	PROPN
admet-442	163	11	)	)	PUNCT
admet-442	163	12	could	could	AUX
admet-442	163	13	regulate	regulate	VERB
admet-442	163	14	activation	activation	NOUN
admet-442	163	15	of	of	ADP
admet-442	163	16	cd8	cd8	PROPN
admet-442	163	17	+	+	PROPN
admet-442	163	18	t	t	PROPN
admet-442	163	19	cell	cell	NOUN
admet-442	163	20	and	and	CCONJ
admet-442	163	21	inhibition	inhibition	NOUN
admet-442	163	22	of	of	ADP
admet-442	163	23	shp-1	shp-1	PUNCT
admet-442	163	24	by	by	ADP
admet-442	163	25	sodium	sodium	NOUN
admet-442	163	26	stibogluconate	stibogluconate	NOUN
admet-442	163	27	enhanced	enhance	VERB
admet-442	163	28	the	the	DET
admet-442	163	29	function	function	NOUN
admet-442	163	30	of	of	ADP
admet-442	163	31	t	t	NOUN
admet-442	163	32	cells	cell	NOUN
admet-442	163	33	[	[	X
admet-442	163	34	82	82	NUM
admet-442	163	35	]	]	PUNCT
admet-442	163	36	.	.	PUNCT
admet-442	164	1	the	the	DET
admet-442	164	2	cytoplasmic	cytoplasmic	ADJ
admet-442	164	3	domain	domain	NOUN
admet-442	164	4	of	of	ADP
admet-442	164	5	pd-1	pd-1	ADJ
admet-442	164	6	consists	consist	NOUN
admet-442	164	7	of	of	ADP
admet-442	164	8	two	two	NUM
admet-442	164	9	motifs	motif	NOUN
admet-442	164	10	,	,	PUNCT
admet-442	164	11	including	include	VERB
admet-442	164	12	the	the	DET
admet-442	164	13	tyrosine	tyrosine	NOUN
admet-442	164	14	-	-	PUNCT
admet-442	164	15	based	base	VERB
admet-442	164	16	inhibitory	inhibitory	ADJ
admet-442	164	17	motif	motif	NOUN
admet-442	164	18	(	(	PUNCT
admet-442	164	19	itim	itim	NOUN
admet-442	164	20	)	)	PUNCT
admet-442	164	21	and	and	CCONJ
admet-442	164	22	immunoreceptor	immunoreceptor	NOUN
admet-442	164	23	tyrosine	tyrosine	NOUN
admet-442	164	24	-	-	PUNCT
admet-442	164	25	based	base	VERB
admet-442	164	26	switch	switch	NOUN
admet-442	164	27	motif	motif	NOUN
admet-442	164	28	(	(	PUNCT
admet-442	164	29	itsm	itsm	NOUN
admet-442	164	30	)	)	PUNCT
admet-442	165	1	[	[	X
admet-442	165	2	83	83	NUM
admet-442	165	3	]	]	PUNCT
admet-442	165	4	.	.	PUNCT
admet-442	166	1	the	the	DET
admet-442	166	2	pd-1	pd-1	ADJ
admet-442	166	3	and	and	CCONJ
admet-442	166	4	pd	pd	PROPN
admet-442	166	5	-	-	PUNCT
admet-442	166	6	l1	l1	PROPN
admet-442	166	7	interaction	interaction	NOUN
admet-442	166	8	can	can	AUX
admet-442	166	9	phosphorylate	phosphorylate	VERB
admet-442	166	10	a	a	DET
admet-442	166	11	tyrosine	tyrosine	NOUN
admet-442	166	12	in	in	ADP
admet-442	166	13	the	the	DET
admet-442	166	14	itsm	itsm	NOUN
admet-442	166	15	motif	motif	NOUN
admet-442	166	16	of	of	ADP
admet-442	166	17	pd-1	pd-1	ADJ
admet-442	166	18	,	,	PUNCT
admet-442	166	19	and	and	CCONJ
admet-442	166	20	then	then	ADV
admet-442	166	21	recruit	recruit	VERB
admet-442	166	22	the	the	DET
admet-442	166	23	shp-1	shp-1	NOUN
admet-442	166	24	and	and	CCONJ
admet-442	166	25	shp2	shp2	NOUN
admet-442	166	26	to	to	ADP
admet-442	166	27	the	the	DET
admet-442	166	28	itsm	itsm	NOUN
admet-442	166	29	motif	motif	NOUN
admet-442	166	30	[	[	X
admet-442	166	31	84	84	NUM
admet-442	166	32	]	]	PUNCT
admet-442	166	33	.	.	PUNCT
admet-442	167	1	after	after	ADP
admet-442	167	2	recruiting	recruit	VERB
admet-442	167	3	,	,	PUNCT
admet-442	167	4	this	this	DET
admet-442	167	5	signaling	signal	VERB
admet-442	167	6	pathway	pathway	NOUN
admet-442	167	7	can	can	AUX
admet-442	167	8	inhibit	inhibit	VERB
admet-442	167	9	stop	stop	VERB
admet-442	167	10	signals	signal	NOUN
admet-442	167	11	,	,	PUNCT
admet-442	167	12	and	and	CCONJ
admet-442	167	13	block	block	VERB
admet-442	167	14	the	the	DET
admet-442	167	15	interaction	interaction	NOUN
admet-442	167	16	of	of	ADP
admet-442	167	17	t	t	NOUN
admet-442	167	18	cells	cell	NOUN
admet-442	167	19	and	and	CCONJ
admet-442	167	20	dendritic	dendritic	ADJ
admet-442	167	21	cells	cell	NOUN
admet-442	167	22	[	[	X
admet-442	167	23	85	85	NUM
admet-442	167	24	]	]	PUNCT
admet-442	167	25	.	.	PUNCT
admet-442	168	1	finally	finally	ADV
admet-442	168	2	,	,	PUNCT
admet-442	168	3	blockade	blockade	NOUN
admet-442	168	4	of	of	ADP
admet-442	168	5	the	the	DET
admet-442	168	6	tcr	tcr	PROPN
admet-442	168	7	signal	signal	PROPN
admet-442	168	8	transduction	transduction	NOUN
admet-442	168	9	caused	cause	VERB
admet-442	168	10	inhibition	inhibition	NOUN
admet-442	168	11	of	of	ADP
admet-442	168	12	the	the	DET
admet-442	168	13	pi3k	pi3k	PROPN
admet-442	168	14	/	/	SYM
admet-442	168	15	akt	akt	PROPN
admet-442	168	16	(	(	PUNCT
admet-442	168	17	akt	akt	PROPN
admet-442	168	18	is	be	AUX
admet-442	168	19	known	know	VERB
admet-442	168	20	as	as	ADP
admet-442	168	21	protein	protein	NOUN
admet-442	168	22	kinase	kinase	PROPN
admet-442	168	23	b	b	PROPN
admet-442	168	24	)	)	PUNCT
admet-442	168	25	and	and	CCONJ
admet-442	168	26	mapk	mapk	NOUN
admet-442	168	27	signaling	signal	VERB
admet-442	168	28	[	[	X
admet-442	168	29	86	86	NUM
admet-442	168	30	]	]	PUNCT
admet-442	168	31	.	.	PUNCT
admet-442	169	1	most	most	ADV
admet-442	169	2	importantly	importantly	ADV
admet-442	169	3	,	,	PUNCT
admet-442	169	4	inhibition	inhibition	NOUN
admet-442	169	5	of	of	ADP
admet-442	169	6	pi3k	pi3k	NOUN
admet-442	169	7	activation	activation	NOUN
admet-442	169	8	suppresses	suppress	VERB
admet-442	169	9	the	the	DET
admet-442	169	10	expression	expression	NOUN
admet-442	169	11	of	of	ADP
admet-442	169	12	b	b	PROPN
admet-442	169	13	cell	cell	NOUN
admet-442	169	14	lymphoma	lymphoma	VERB
admet-442	169	15	extra	extra	ADJ
admet-442	169	16	-	-	ADJ
admet-442	169	17	large	large	ADJ
admet-442	169	18	(	(	PUNCT
admet-442	169	19	bcl	bcl	NOUN
admet-442	169	20	-	-	PROPN
admet-442	169	21	xl	xl	PROPN
admet-442	169	22	)	)	PUNCT
admet-442	169	23	and	and	CCONJ
admet-442	169	24	activation	activation	NOUN
admet-442	169	25	of	of	ADP
admet-442	169	26	akt	akt	PROPN
admet-442	169	27	,	,	PUNCT
admet-442	169	28	which	which	PRON
admet-442	169	29	furtherly	furtherly	ADV
admet-442	169	30	leads	lead	VERB
admet-442	169	31	to	to	ADP
admet-442	169	32	increased	increase	VERB
admet-442	169	33	apoptosis	apoptosis	NOUN
admet-442	169	34	of	of	ADP
admet-442	169	35	t	t	NOUN
admet-442	169	36	cells	cell	NOUN
admet-442	169	37	[	[	X
admet-442	169	38	12	12	NUM
admet-442	169	39	]	]	PUNCT
admet-442	169	40	.	.	PUNCT
admet-442	170	1	pd	pd	PROPN
admet-442	170	2	-	-	PROPN
admet-442	170	3	l1	l1	PROPN
admet-442	170	4	not	not	PART
admet-442	170	5	only	only	ADV
admet-442	170	6	inhibits	inhibit	VERB
admet-442	170	7	function	function	NOUN
admet-442	170	8	of	of	ADP
admet-442	170	9	activated	activate	VERB
admet-442	170	10	t	t	NOUN
admet-442	170	11	cell	cell	NOUN
admet-442	170	12	via	via	ADP
admet-442	170	13	inhibition	inhibition	NOUN
admet-442	170	14	of	of	ADP
admet-442	170	15	pi3k	pi3k	PROPN
admet-442	170	16	/	/	SYM
admet-442	170	17	akt	akt	PROPN
admet-442	170	18	pathway	pathway	NOUN
admet-442	170	19	and	and	CCONJ
admet-442	170	20	ras	ras	PROPN
admet-442	170	21	/	/	SYM
admet-442	170	22	mek	mek	PROPN
admet-442	170	23	/	/	SYM
admet-442	170	24	erk	erk	PROPN
admet-442	170	25	pathway	pathway	NOUN
admet-442	170	26	,	,	PUNCT
admet-442	170	27	but	but	CCONJ
admet-442	170	28	also	also	ADV
admet-442	170	29	through	through	ADP
admet-442	170	30	inhibition	inhibition	NOUN
admet-442	170	31	of	of	ADP
admet-442	170	32	transcription	transcription	NOUN
admet-442	170	33	factors	factor	NOUN
admet-442	170	34	necessary	necessary	ADJ
admet-442	170	35	for	for	ADP
admet-442	170	36	t	t	PROPN
admet-442	170	37	cell	cell	NOUN
admet-442	170	38	survival	survival	NOUN
admet-442	170	39	.	.	PUNCT
admet-442	171	1	pd	pd	PROPN
admet-442	171	2	-	-	PROPN
admet-442	171	3	l1	l1	PROPN
admet-442	171	4	and	and	CCONJ
admet-442	171	5	pd-1	pd-1	ADJ
admet-442	171	6	interaction	interaction	NOUN
admet-442	171	7	was	be	AUX
admet-442	171	8	reported	report	VERB
admet-442	171	9	to	to	PART
admet-442	171	10	inhibit	inhibit	VERB
admet-442	171	11	expression	expression	NOUN
admet-442	171	12	of	of	ADP
admet-442	171	13	gata-3	gata-3	PROPN
admet-442	171	14	and	and	CCONJ
admet-442	171	15	t	t	PROPN
admet-442	171	16	-	-	PUNCT
admet-442	171	17	bet	bet	NOUN
admet-442	172	1	[	[	X
admet-442	172	2	87	87	NUM
admet-442	172	3	]	]	PUNCT
admet-442	172	4	.	.	PUNCT
admet-442	173	1	gata-3	gata-3	PROPN
admet-442	173	2	has	have	AUX
admet-442	173	3	been	be	AUX
admet-442	173	4	reported	report	VERB
admet-442	173	5	to	to	PART
admet-442	173	6	be	be	AUX
admet-442	173	7	a	a	DET
admet-442	173	8	admet	admet	NOUN
admet-442	173	9	&	&	CCONJ
admet-442	173	10	dmpk	dmpk	PROPN
admet-442	173	11	5(3	5(3	NUM
admet-442	173	12	)	)	PUNCT
admet-442	173	13	(	(	PUNCT
admet-442	173	14	2017	2017	NUM
admet-442	173	15	)	)	PUNCT
admet-442	173	16	159	159	NUM
admet-442	173	17	-	-	SYM
admet-442	173	18	172	172	NUM
admet-442	173	19	the	the	DET
admet-442	173	20	function	function	NOUN
admet-442	173	21	and	and	CCONJ
admet-442	173	22	regulation	regulation	NOUN
admet-442	173	23	of	of	ADP
admet-442	173	24	pd	pd	PROPN
admet-442	173	25	-	-	PROPN
admet-442	173	26	l1	l1	PROPN
admet-442	173	27	in	in	ADP
admet-442	173	28	immunotherapy	immunotherapy	NOUN
admet-442	173	29	doi	doi	NOUN
admet-442	173	30	:	:	PUNCT
admet-442	173	31	10.5599	10.5599	NUM
admet-442	173	32	/	/	SYM
admet-442	173	33	admet.5.3.442	admet.5.3.442	NUM
admet-442	173	34	165	165	NUM
admet-442	173	35	transcription	transcription	NOUN
admet-442	173	36	factor	factor	NOUN
admet-442	173	37	which	which	PRON
admet-442	173	38	is	be	AUX
admet-442	173	39	critical	critical	ADJ
admet-442	173	40	for	for	ADP
admet-442	173	41	differentiation	differentiation	NOUN
admet-442	173	42	of	of	ADP
admet-442	173	43	t	t	PROPN
admet-442	173	44	helper	helper	NOUN
admet-442	173	45	2	2	NUM
admet-442	173	46	(	(	PUNCT
admet-442	173	47	th2	th2	PROPN
admet-442	173	48	)	)	PUNCT
admet-442	173	49	cells	cell	NOUN
admet-442	173	50	[	[	X
admet-442	173	51	21	21	NUM
admet-442	173	52	]	]	PUNCT
admet-442	173	53	.	.	PUNCT
admet-442	174	1	meanwhile	meanwhile	ADV
admet-442	174	2	,	,	PUNCT
admet-442	174	3	t	t	PROPN
admet-442	174	4	-	-	PUNCT
admet-442	174	5	bet	bet	NOUN
admet-442	174	6	,	,	PUNCT
admet-442	174	7	which	which	PRON
admet-442	174	8	is	be	AUX
admet-442	174	9	known	know	VERB
admet-442	174	10	as	as	ADP
admet-442	174	11	t	t	PROPN
admet-442	174	12	-	-	PUNCT
admet-442	174	13	box	box	NOUN
admet-442	174	14	transcription	transcription	NOUN
admet-442	174	15	factor	factor	NOUN
admet-442	174	16	,	,	PUNCT
admet-442	174	17	can	can	AUX
admet-442	174	18	contribute	contribute	VERB
admet-442	174	19	to	to	ADP
admet-442	174	20	t	t	NOUN
admet-442	174	21	-	-	PUNCT
admet-442	174	22	cell	cell	NOUN
admet-442	174	23	development	development	NOUN
admet-442	174	24	[	[	X
admet-442	174	25	88	88	NUM
admet-442	174	26	]	]	PUNCT
admet-442	174	27	.	.	PUNCT
admet-442	175	1	pd	pd	PROPN
admet-442	175	2	-	-	PUNCT
admet-442	175	3	l1	l1	PROPN
admet-442	175	4	/	/	SYM
admet-442	175	5	pd-1	pd-1	NOUN
admet-442	175	6	interaction	interaction	NOUN
admet-442	175	7	is	be	AUX
admet-442	175	8	also	also	ADV
admet-442	175	9	involved	involve	VERB
admet-442	175	10	in	in	ADP
admet-442	175	11	signal	signal	ADJ
admet-442	175	12	pathway	pathway	NOUN
admet-442	175	13	mediated	mediate	VERB
admet-442	175	14	by	by	ADP
admet-442	175	15	tgf	tgf	PROPN
admet-442	175	16	-	-	PUNCT
admet-442	175	17	β	β	NOUN
admet-442	175	18	.	.	PUNCT
admet-442	176	1	loise	loise	PROPN
admet-442	176	2	et	et	PROPN
admet-442	176	3	al	al	PROPN
admet-442	176	4	.	.	PROPN
admet-442	176	5	reported	report	VERB
admet-442	176	6	that	that	SCONJ
admet-442	176	7	the	the	DET
admet-442	176	8	function	function	NOUN
admet-442	176	9	of	of	ADP
admet-442	176	10	tgf	tgf	PROPN
admet-442	176	11	-	-	PUNCT
admet-442	176	12	β	β	PROPN
admet-442	176	13	in	in	ADP
admet-442	176	14	induced	induce	VERB
admet-442	176	15	t	t	PROPN
admet-442	176	16	cell	cell	NOUN
admet-442	176	17	regulatory	regulatory	ADJ
admet-442	176	18	(	(	PUNCT
admet-442	176	19	itreg	itreg	PROPN
admet-442	176	20	)	)	PUNCT
admet-442	176	21	cell	cell	NOUN
admet-442	176	22	development	development	NOUN
admet-442	176	23	could	could	AUX
admet-442	176	24	be	be	AUX
admet-442	176	25	reduced	reduce	VERB
admet-442	176	26	by	by	ADP
admet-442	176	27	the	the	DET
admet-442	176	28	loss	loss	NOUN
admet-442	176	29	of	of	ADP
admet-442	176	30	pd	pd	PROPN
admet-442	176	31	-	-	PROPN
admet-442	176	32	l1	l1	PROPN
admet-442	176	33	[	[	X
admet-442	176	34	89	89	NUM
admet-442	176	35	]	]	PUNCT
admet-442	176	36	.	.	PUNCT
admet-442	177	1	this	this	DET
admet-442	177	2	study	study	NOUN
admet-442	177	3	also	also	ADV
admet-442	177	4	reported	report	VERB
admet-442	177	5	that	that	SCONJ
admet-442	177	6	during	during	ADP
admet-442	177	7	the	the	DET
admet-442	177	8	conversion	conversion	NOUN
admet-442	177	9	of	of	ADP
admet-442	177	10	itreg	itreg	NOUN
admet-442	177	11	cells	cell	NOUN
admet-442	177	12	from	from	ADP
admet-442	177	13	mature	mature	ADJ
admet-442	177	14	t	t	NOUN
admet-442	177	15	cells	cell	NOUN
admet-442	177	16	,	,	PUNCT
admet-442	177	17	pd	pd	PROPN
admet-442	177	18	-	-	PUNCT
admet-442	177	19	l1	l1	NOUN
admet-442	177	20	/	/	SYM
admet-442	177	21	pd1	pd1	NOUN
admet-442	177	22	signaling	signal	VERB
admet-442	177	23	reduced	reduce	VERB
admet-442	177	24	the	the	DET
admet-442	177	25	phosphorylation	phosphorylation	NOUN
admet-442	177	26	of	of	ADP
admet-442	177	27	akt	akt	PROPN
admet-442	177	28	and	and	CCONJ
admet-442	177	29	its	its	PRON
admet-442	177	30	downstream	downstream	ADJ
admet-442	177	31	substrates	substrate	NOUN
admet-442	177	32	mtor	mtor	NOUN
admet-442	177	33	and	and	CCONJ
admet-442	177	34	s6	s6	PROPN
admet-442	178	1	[	[	X
admet-442	178	2	89	89	NUM
admet-442	178	3	]	]	PUNCT
admet-442	178	4	.	.	PUNCT
admet-442	179	1	barber	barber	PROPN
admet-442	179	2	et	et	PROPN
admet-442	179	3	al	al	PROPN
admet-442	179	4	.	.	PROPN
admet-442	179	5	reported	report	VERB
admet-442	179	6	that	that	SCONJ
admet-442	179	7	in	in	ADP
admet-442	179	8	exhausted	exhausted	ADJ
admet-442	179	9	cd8	cd8	PROPN
admet-442	179	10	+	+	PROPN
admet-442	179	11	t	t	PROPN
admet-442	179	12	cell	cell	NOUN
admet-442	179	13	blockade	blockade	NOUN
admet-442	179	14	of	of	ADP
admet-442	179	15	pd	pd	PROPN
admet-442	179	16	-	-	PROPN
admet-442	179	17	l1	l1	PROPN
admet-442	179	18	and	and	CCONJ
admet-442	179	19	pd-1	pd-1	ADV
admet-442	179	20	signaling	signal	VERB
admet-442	179	21	pathway	pathway	NOUN
admet-442	179	22	enhanced	enhance	VERB
admet-442	179	23	t	t	NOUN
admet-442	179	24	cell	cell	NOUN
admet-442	179	25	ability	ability	NOUN
admet-442	179	26	to	to	PART
admet-442	179	27	secrete	secrete	VERB
admet-442	179	28	cytokine	cytokine	VERB
admet-442	179	29	and	and	CCONJ
admet-442	179	30	kill	kill	VERB
admet-442	179	31	infected	infected	ADJ
admet-442	179	32	cells	cell	NOUN
admet-442	179	33	with	with	ADP
admet-442	179	34	lcmv	lcmv	PROPN
admet-442	179	35	,	,	PUNCT
admet-442	179	36	suggesting	suggest	VERB
admet-442	179	37	that	that	SCONJ
admet-442	179	38	the	the	DET
admet-442	179	39	pd	pd	PROPN
admet-442	179	40	-	-	PUNCT
admet-442	179	41	l1	l1	PROPN
admet-442	179	42	/	/	SYM
admet-442	179	43	pd-1	pd-1	VERB
admet-442	179	44	signaling	signal	VERB
admet-442	179	45	pathway	pathway	NOUN
admet-442	179	46	affected	affect	VERB
admet-442	179	47	activation	activation	NOUN
admet-442	179	48	of	of	ADP
admet-442	179	49	downstream	downstream	ADJ
admet-442	179	50	molecules	molecule	NOUN
admet-442	179	51	of	of	ADP
admet-442	179	52	the	the	DET
admet-442	179	53	t	t	NOUN
admet-442	179	54	cell	cell	NOUN
admet-442	179	55	activation	activation	NOUN
admet-442	179	56	[	[	X
admet-442	179	57	51	51	NUM
admet-442	179	58	]	]	PUNCT
admet-442	179	59	.	.	PUNCT
admet-442	180	1	the	the	DET
admet-442	180	2	study	study	NOUN
admet-442	180	3	reported	report	VERB
admet-442	180	4	by	by	ADP
admet-442	180	5	carter	carter	PROPN
admet-442	180	6	et	et	PROPN
admet-442	180	7	al	al	PROPN
admet-442	180	8	.	.	PROPN
admet-442	180	9	showed	show	VERB
admet-442	180	10	that	that	SCONJ
admet-442	180	11	pd	pd	PROPN
admet-442	180	12	-	-	PROPN
admet-442	180	13	l1	l1	PROPN
admet-442	180	14	and	and	CCONJ
admet-442	180	15	pd-1	pd-1	ADV
admet-442	180	16	interaction	interaction	NOUN
admet-442	180	17	inhibited	inhibit	VERB
admet-442	180	18	il-2	il-2	NUM
admet-442	180	19	production	production	NOUN
admet-442	180	20	in	in	ADP
admet-442	180	21	cd4	cd4	PROPN
admet-442	180	22	+	+	PROPN
admet-442	180	23	and	and	CCONJ
admet-442	180	24	cd8	cd8	PROPN
admet-442	180	25	+	+	PROPN
admet-442	180	26	t	t	NOUN
admet-442	180	27	cell	cell	NOUN
admet-442	180	28	,	,	PUNCT
admet-442	180	29	which	which	PRON
admet-442	180	30	further	far	ADV
admet-442	180	31	inhibited	inhibit	VERB
admet-442	180	32	lymphoproliferation	lymphoproliferation	NOUN
admet-442	181	1	[	[	X
admet-442	181	2	90	90	NUM
admet-442	181	3	]	]	PUNCT
admet-442	181	4	.	.	PUNCT
admet-442	182	1	in	in	ADP
admet-442	182	2	endothelial	endothelial	ADJ
admet-442	182	3	cells	cell	NOUN
admet-442	182	4	mouse	mouse	VERB
admet-442	182	5	anti	anti	ADJ
admet-442	182	6	-	-	ADJ
admet-442	182	7	pd	pd	ADJ
admet-442	182	8	-	-	PUNCT
admet-442	182	9	l1	l1	PROPN
admet-442	182	10	blocked	block	VERB
admet-442	182	11	the	the	DET
admet-442	182	12	interaction	interaction	NOUN
admet-442	182	13	of	of	ADP
admet-442	182	14	pd	pd	PROPN
admet-442	182	15	-	-	PROPN
admet-442	182	16	l1	l1	PROPN
admet-442	182	17	and	and	CCONJ
admet-442	182	18	pd	pd	PROPN
admet-442	182	19	-	-	PROPN
admet-442	182	20	l	l	NOUN
admet-442	182	21	,	,	PUNCT
admet-442	182	22	and	and	CCONJ
admet-442	182	23	stimulated	stimulate	VERB
admet-442	182	24	ifn	ifn	PROPN
admet-442	182	25	-	-	PUNCT
admet-442	182	26	γ	γ	NOUN
admet-442	182	27	production	production	NOUN
admet-442	182	28	secreted	secrete	VERB
admet-442	182	29	by	by	ADP
admet-442	182	30	cd8	cd8	PROPN
admet-442	182	31	+	+	PROPN
admet-442	182	32	t	t	PROPN
admet-442	182	33	cell	cell	NOUN
admet-442	182	34	,	,	PUNCT
admet-442	182	35	resulting	result	VERB
admet-442	182	36	in	in	ADP
admet-442	182	37	t	t	PROPN
admet-442	182	38	cell	cell	NOUN
admet-442	182	39	activation	activation	NOUN
admet-442	182	40	[	[	X
admet-442	182	41	91	91	NUM
admet-442	182	42	]	]	PUNCT
admet-442	182	43	.	.	PUNCT
admet-442	183	1	in	in	ADP
admet-442	183	2	hodgkin	hodgkin	PROPN
admet-442	183	3	lymphoma	lymphoma	PROPN
admet-442	183	4	-infiltrating	-infiltrating	PROPN
admet-442	183	5	t	t	NOUN
admet-442	183	6	cells	cell	NOUN
admet-442	183	7	,	,	PUNCT
admet-442	183	8	inhibition	inhibition	NOUN
admet-442	183	9	of	of	ADP
admet-442	183	10	the	the	DET
admet-442	183	11	activation	activation	NOUN
admet-442	183	12	of	of	ADP
admet-442	183	13	pd-1	pd-1	ADJ
admet-442	183	14	and	and	CCONJ
admet-442	183	15	pd	pd	PROPN
admet-442	183	16	-	-	PROPN
admet-442	183	17	l1	l1	PROPN
admet-442	183	18	signaling	signal	VERB
admet-442	183	19	pathway	pathway	NOUN
admet-442	183	20	led	lead	VERB
admet-442	183	21	to	to	ADP
admet-442	183	22	inhibition	inhibition	NOUN
admet-442	183	23	of	of	ADP
admet-442	183	24	shp-2	shp-2	ADJ
admet-442	183	25	phosphorylation	phosphorylation	NOUN
admet-442	183	26	and	and	CCONJ
admet-442	183	27	increased	increase	VERB
admet-442	183	28	the	the	DET
admet-442	183	29	production	production	NOUN
admet-442	183	30	of	of	ADP
admet-442	183	31	ifn	ifn	PROPN
admet-442	183	32	-	-	PUNCT
admet-442	183	33	γ	γ	NOUN
admet-442	183	34	[	[	X
admet-442	183	35	92	92	NUM
admet-442	183	36	]	]	PUNCT
admet-442	183	37	.	.	PUNCT
admet-442	184	1	in	in	ADP
admet-442	184	2	the	the	DET
admet-442	184	3	liver	liver	NOUN
admet-442	184	4	pd	pd	PROPN
admet-442	184	5	-	-	PROPN
admet-442	184	6	l1	l1	PROPN
admet-442	184	7	and	and	CCONJ
admet-442	184	8	pd-1	pd-1	ADV
admet-442	184	9	interaction	interaction	NOUN
admet-442	184	10	led	lead	VERB
admet-442	184	11	to	to	AUX
admet-442	184	12	reduced	reduce	VERB
admet-442	184	13	ifn	ifn	PROPN
admet-442	184	14	-	-	PUNCT
admet-442	184	15	γ	γ	NOUN
admet-442	184	16	production	production	NOUN
admet-442	184	17	secreted	secrete	VERB
admet-442	184	18	by	by	ADP
admet-442	184	19	cd8	cd8	PROPN
admet-442	184	20	+	+	PROPN
admet-442	184	21	t	t	PROPN
admet-442	184	22	lymphocytes(clt	lymphocytes(clt	NOUN
admet-442	184	23	)	)	PUNCT
admet-442	185	1	[	[	X
admet-442	185	2	50	50	NUM
admet-442	185	3	]	]	PUNCT
admet-442	185	4	.	.	PUNCT
admet-442	186	1	figure	figure	NOUN
admet-442	186	2	3	3	NUM
admet-442	186	3	.	.	PUNCT
admet-442	187	1	the	the	DET
admet-442	187	2	pd	pd	PROPN
admet-442	187	3	-	-	PUNCT
admet-442	187	4	l1	l1	PROPN
admet-442	187	5	/	/	SYM
admet-442	187	6	pd-1	pd-1	VERB
admet-442	187	7	signaling	signal	VERB
admet-442	187	8	pathway	pathway	NOUN
admet-442	187	9	in	in	ADP
admet-442	187	10	t	t	NOUN
admet-442	187	11	cells	cell	NOUN
admet-442	187	12	.	.	PUNCT
admet-442	188	1	pd	pd	PROPN
admet-442	188	2	-	-	PUNCT
admet-442	188	3	l1	l1	PROPN
admet-442	188	4	/	/	SYM
admet-442	188	5	pd1	pd1	NOUN
admet-442	188	6	signaling	signal	VERB
admet-442	188	7	pathway	pathway	NOUN
admet-442	188	8	could	could	AUX
admet-442	188	9	mediate	mediate	VERB
admet-442	188	10	t	t	PROPN
admet-442	188	11	cell	cell	NOUN
admet-442	188	12	survival	survival	NOUN
admet-442	188	13	through	through	ADP
admet-442	188	14	regulation	regulation	NOUN
admet-442	188	15	of	of	ADP
admet-442	188	16	different	different	ADJ
admet-442	188	17	signal	signal	NOUN
admet-442	188	18	transductions	transduction	NOUN
admet-442	188	19	.	.	PUNCT
admet-442	189	1	pd-1	pd-1	ADJ
admet-442	189	2	and	and	CCONJ
admet-442	189	3	pd	pd	PROPN
admet-442	189	4	-	-	PROPN
admet-442	189	5	l1	l1	PROPN
admet-442	189	6	interaction	interaction	NOUN
admet-442	189	7	leads	lead	VERB
admet-442	189	8	to	to	ADP
admet-442	189	9	pd-1	pd-1	ADJ
admet-442	189	10	phosphorylation	phosphorylation	NOUN
admet-442	189	11	,	,	PUNCT
admet-442	189	12	and	and	CCONJ
admet-442	189	13	recruits	recruit	NOUN
admet-442	189	14	shp-1	shp-1	NUM
admet-442	189	15	and	and	CCONJ
admet-442	189	16	shp2	shp2	NOUN
admet-442	189	17	to	to	ADP
admet-442	189	18	the	the	DET
admet-442	189	19	itsm	itsm	NOUN
admet-442	189	20	motif	motif	NOUN
admet-442	189	21	of	of	ADP
admet-442	189	22	pd-1	pd-1	ADJ
admet-442	189	23	.	.	PUNCT
admet-442	190	1	after	after	ADP
admet-442	190	2	recruiting	recruit	VERB
admet-442	190	3	,	,	PUNCT
admet-442	190	4	this	this	DET
admet-442	190	5	signaling	signal	VERB
admet-442	190	6	pathway	pathway	NOUN
admet-442	190	7	blocks	block	VERB
admet-442	190	8	the	the	DET
admet-442	190	9	interaction	interaction	NOUN
admet-442	190	10	of	of	ADP
admet-442	190	11	t	t	NOUN
admet-442	190	12	cells	cell	NOUN
admet-442	190	13	.	.	PUNCT
admet-442	191	1	blockade	blockade	NOUN
admet-442	191	2	of	of	ADP
admet-442	191	3	tcr	tcr	PROPN
admet-442	191	4	signal	signal	PROPN
admet-442	191	5	transduction	transduction	NOUN
admet-442	191	6	inhibited	inhibit	VERB
admet-442	191	7	the	the	DET
admet-442	191	8	pi3k	pi3k	PROPN
admet-442	191	9	/	/	SYM
admet-442	191	10	akt	akt	PROPN
admet-442	191	11	and	and	CCONJ
admet-442	191	12	mapk	mapk	NOUN
admet-442	191	13	signaling	signal	VERB
admet-442	191	14	.	.	PUNCT
admet-442	192	1	inhibition	inhibition	NOUN
admet-442	192	2	of	of	ADP
admet-442	192	3	pi3k	pi3k	NOUN
admet-442	192	4	activation	activation	NOUN
admet-442	192	5	suppressed	suppress	VERB
admet-442	192	6	the	the	DET
admet-442	192	7	expression	expression	NOUN
admet-442	192	8	of	of	ADP
admet-442	192	9	b	b	PROPN
admet-442	192	10	cell	cell	NOUN
admet-442	192	11	lymphoma	lymphoma	VERB
admet-442	192	12	extra	extra	ADJ
admet-442	192	13	-	-	ADJ
admet-442	192	14	large	large	ADJ
admet-442	192	15	(	(	PUNCT
admet-442	192	16	bcl	bcl	NOUN
admet-442	192	17	-	-	PROPN
admet-442	192	18	xl	xl	PROPN
admet-442	192	19	)	)	PUNCT
admet-442	192	20	and	and	CCONJ
admet-442	192	21	activation	activation	NOUN
admet-442	192	22	of	of	ADP
admet-442	192	23	akt	akt	PROPN
admet-442	192	24	,	,	PUNCT
admet-442	192	25	which	which	PRON
admet-442	192	26	leads	lead	VERB
admet-442	192	27	to	to	ADP
admet-442	192	28	increased	increase	VERB
admet-442	192	29	apoptosis	apoptosis	NOUN
admet-442	192	30	of	of	ADP
admet-442	192	31	t	t	NOUN
admet-442	192	32	cells	cell	NOUN
admet-442	192	33	.	.	PUNCT
admet-442	193	1	pd	pd	PROPN
admet-442	193	2	-	-	PROPN
admet-442	193	3	l1	l1	PROPN
admet-442	193	4	and	and	CCONJ
admet-442	193	5	pd-1	pd-1	VERB
admet-442	193	6	interaction	interaction	NOUN
admet-442	193	7	also	also	ADV
admet-442	193	8	inhibits	inhibit	VERB
admet-442	193	9	expression	expression	NOUN
admet-442	193	10	of	of	ADP
admet-442	193	11	gata-3	gata-3	PROPN
admet-442	193	12	and	and	CCONJ
admet-442	193	13	t	t	PROPN
admet-442	193	14	-	-	PUNCT
admet-442	193	15	bet	bet	NOUN
admet-442	193	16	.	.	PUNCT
admet-442	194	1	gata-3	gata-3	PROPN
admet-442	194	2	is	be	AUX
admet-442	194	3	critical	critical	ADJ
admet-442	194	4	for	for	ADP
admet-442	194	5	differentiation	differentiation	NOUN
admet-442	194	6	of	of	ADP
admet-442	194	7	th2	th2	PROPN
admet-442	194	8	cells	cell	NOUN
admet-442	194	9	.	.	PUNCT
admet-442	195	1	t	t	NOUN
admet-442	195	2	-	-	PUNCT
admet-442	195	3	bet	bet	NOUN
admet-442	195	4	contributes	contribute	VERB
admet-442	195	5	to	to	ADP
admet-442	195	6	t	t	NOUN
admet-442	195	7	-	-	PUNCT
admet-442	195	8	cell	cell	NOUN
admet-442	195	9	development	development	NOUN
admet-442	195	10	.	.	PUNCT
admet-442	196	1	conclusions	conclusion	NOUN
admet-442	196	2	this	this	DET
admet-442	196	3	review	review	NOUN
admet-442	196	4	describes	describe	VERB
admet-442	196	5	the	the	DET
admet-442	196	6	regulation	regulation	NOUN
admet-442	196	7	of	of	ADP
admet-442	196	8	the	the	DET
admet-442	196	9	pd	pd	PROPN
admet-442	196	10	-	-	PUNCT
admet-442	196	11	l1	l1	PROPN
admet-442	196	12	/	/	SYM
admet-442	196	13	pd-1	pd-1	NOUN
admet-442	196	14	signaling	signal	VERB
admet-442	196	15	pathway	pathway	NOUN
admet-442	196	16	.	.	PUNCT
admet-442	197	1	pd	pd	PROPN
admet-442	197	2	-	-	PROPN
admet-442	197	3	l1	l1	PROPN
admet-442	197	4	is	be	AUX
admet-442	197	5	a	a	DET
admet-442	197	6	transmembrane	transmembrane	ADJ
admet-442	197	7	protein	protein	NOUN
admet-442	197	8	,	,	PUNCT
admet-442	197	9	and	and	CCONJ
admet-442	197	10	inhibits	inhibit	VERB
admet-442	197	11	the	the	DET
admet-442	197	12	function	function	NOUN
admet-442	197	13	of	of	ADP
admet-442	197	14	t	t	PROPN
admet-442	197	15	cell	cell	NOUN
admet-442	197	16	through	through	ADP
admet-442	197	17	binding	bind	VERB
admet-442	197	18	to	to	ADP
admet-442	197	19	its	its	PRON
admet-442	197	20	receptor	receptor	NOUN
admet-442	197	21	pd-1	pd-1	ADP
admet-442	197	22	.	.	PUNCT
admet-442	198	1	the	the	DET
admet-442	198	2	interaction	interaction	NOUN
admet-442	198	3	of	of	ADP
admet-442	198	4	pd	pd	PROPN
admet-442	198	5	-	-	PROPN
admet-442	198	6	l1	l1	PROPN
admet-442	198	7	and	and	CCONJ
admet-442	198	8	pd-1	pd-1	ADJ
admet-442	198	9	inhibits	inhibit	VERB
admet-442	198	10	t	t	NOUN
admet-442	198	11	cell	cell	NOUN
admet-442	198	12	activation	activation	NOUN
admet-442	198	13	and	and	CCONJ
admet-442	198	14	proliferation	proliferation	NOUN
admet-442	198	15	,	,	PUNCT
admet-442	198	16	which	which	PRON
admet-442	198	17	inhibits	inhibit	VERB
admet-442	198	18	the	the	DET
admet-442	198	19	function	function	NOUN
admet-442	198	20	of	of	ADP
admet-442	198	21	t	t	PROPN
admet-442	198	22	cells	cell	NOUN
admet-442	198	23	to	to	PART
admet-442	198	24	produce	produce	VERB
admet-442	198	25	cytokines	cytokine	NOUN
admet-442	198	26	and	and	CCONJ
admet-442	198	27	kill	kill	VERB
admet-442	198	28	targeting	target	VERB
admet-442	198	29	tumor	tumor	NOUN
admet-442	198	30	cells	cell	NOUN
admet-442	198	31	.	.	PUNCT
admet-442	199	1	blockade	blockade	NOUN
admet-442	199	2	of	of	ADP
admet-442	199	3	pd	pd	PROPN
admet-442	199	4	-	-	PROPN
admet-442	199	5	l1	l1	PROPN
admet-442	199	6	signaling	signal	VERB
admet-442	199	7	by	by	ADP
admet-442	199	8	anti	anti	ADJ
admet-442	199	9	-	-	ADJ
admet-442	199	10	pd	pd	ADJ
admet-442	199	11	-	-	PUNCT
admet-442	199	12	l1	l1	PROPN
admet-442	199	13	antibodies	antibodie	VERB
admet-442	199	14	not	not	PART
admet-442	199	15	only	only	ADV
admet-442	199	16	guo	guo	PROPN
admet-442	199	17	,	,	PUNCT
admet-442	199	18	lin	lin	PROPN
admet-442	199	19	and	and	CCONJ
admet-442	199	20	kwok	kwok	PROPN
admet-442	199	21	admet	admet	PROPN
admet-442	199	22	&	&	CCONJ
admet-442	199	23	dmpk	dmpk	PROPN
admet-442	199	24	5(3	5(3	NUM
admet-442	199	25	)	)	PUNCT
admet-442	199	26	(	(	PUNCT
admet-442	199	27	2017	2017	NUM
admet-442	199	28	)	)	PUNCT
admet-442	199	29	159	159	NUM
admet-442	199	30	-	-	SYM
admet-442	199	31	172	172	NUM
admet-442	199	32	166	166	NUM
admet-442	199	33	inhibits	inhibit	VERB
admet-442	199	34	tumor	tumor	NOUN
admet-442	199	35	growth	growth	NOUN
admet-442	199	36	,	,	PUNCT
admet-442	199	37	but	but	CCONJ
admet-442	199	38	also	also	ADV
admet-442	199	39	leads	lead	VERB
admet-442	199	40	to	to	PART
admet-442	199	41	etiopathogenetic	etiopathogenetic	ADJ
admet-442	199	42	of	of	ADP
admet-442	199	43	autoimmune	autoimmune	ADJ
admet-442	199	44	diseases	disease	NOUN
admet-442	199	45	(	(	PUNCT
admet-442	199	46	such	such	ADJ
admet-442	199	47	as	as	ADP
admet-442	199	48	diabetes	diabete	NOUN
admet-442	199	49	)	)	PUNCT
admet-442	199	50	.	.	PUNCT
admet-442	200	1	there	there	PRON
admet-442	200	2	are	be	VERB
admet-442	200	3	several	several	ADJ
admet-442	200	4	kinds	kind	NOUN
admet-442	200	5	of	of	ADP
admet-442	200	6	antibodies	antibody	NOUN
admet-442	200	7	in	in	ADP
admet-442	200	8	development	development	NOUN
admet-442	200	9	against	against	ADP
admet-442	200	10	pd	pd	PROPN
admet-442	200	11	-	-	PROPN
admet-442	200	12	l1	l1	PROPN
admet-442	200	13	in	in	ADP
admet-442	200	14	cancer	cancer	NOUN
admet-442	200	15	immunotherapy	immunotherapy	NOUN
admet-442	200	16	,	,	PUNCT
admet-442	200	17	such	such	ADJ
admet-442	200	18	as	as	ADP
admet-442	200	19	atezolizumab	atezolizumab	NOUN
admet-442	200	20	,	,	PUNCT
admet-442	200	21	avelumab	avelumab	ADJ
admet-442	200	22	,	,	PUNCT
admet-442	200	23	durvalumab	durvalumab	NOUN
admet-442	200	24	,	,	PUNCT
admet-442	200	25	bms-936559	bms-936559	NOUN
admet-442	200	26	.	.	PUNCT
admet-442	201	1	the	the	DET
admet-442	201	2	safety	safety	NOUN
admet-442	201	3	study	study	NOUN
admet-442	201	4	with	with	ADP
admet-442	201	5	bms-936659	bms-936659	NOUN
admet-442	201	6	showed	show	VERB
admet-442	201	7	that	that	SCONJ
admet-442	201	8	in	in	ADP
admet-442	201	9	39	39	NUM
admet-442	201	10	%	%	NOUN
admet-442	201	11	patient	patient	ADJ
admet-442	201	12	side	side	NOUN
admet-442	201	13	effects	effect	NOUN
admet-442	201	14	such	such	ADJ
admet-442	201	15	as	as	ADP
admet-442	201	16	rash	rash	ADJ
admet-442	201	17	,	,	PUNCT
admet-442	201	18	hypothyroidism	hypothyroidism	NOUN
admet-442	201	19	,	,	PUNCT
admet-442	201	20	diabetes	diabetes	NOUN
admet-442	201	21	mellitus	mellitus	NOUN
admet-442	201	22	,	,	PUNCT
admet-442	201	23	myasthenia	myasthenia	NOUN
admet-442	201	24	gravis	gravis	NOUN
admet-442	201	25	and	and	CCONJ
admet-442	201	26	other	other	ADJ
admet-442	201	27	disease	disease	NOUN
admet-442	201	28	occurred	occur	VERB
admet-442	201	29	[	[	X
admet-442	201	30	93	93	NUM
admet-442	201	31	]	]	PUNCT
admet-442	201	32	.	.	PUNCT
admet-442	202	1	this	this	PRON
admet-442	202	2	makes	make	VERB
admet-442	202	3	pd	pd	NOUN
admet-442	202	4	-	-	PROPN
admet-442	202	5	l1	l1	PROPN
admet-442	202	6	an	an	DET
admet-442	202	7	attractive	attractive	ADJ
admet-442	202	8	target	target	NOUN
admet-442	202	9	for	for	ADP
admet-442	202	10	anti	anti	ADJ
admet-442	202	11	-	-	ADJ
admet-442	202	12	cancer	cancer	ADJ
admet-442	202	13	therapy	therapy	NOUN
admet-442	202	14	.	.	PUNCT
admet-442	203	1	however	however	ADV
admet-442	203	2	,	,	PUNCT
admet-442	203	3	knowledge	knowledge	NOUN
admet-442	203	4	on	on	ADP
admet-442	203	5	the	the	DET
admet-442	203	6	side	side	NOUN
admet-442	203	7	effects	effect	NOUN
admet-442	203	8	of	of	ADP
admet-442	203	9	anti	anti	ADJ
admet-442	203	10	-	-	ADJ
admet-442	203	11	pd	pd	ADJ
admet-442	203	12	-	-	PUNCT
admet-442	203	13	l1	l1	PROPN
admet-442	203	14	therapy	therapy	NOUN
admet-442	203	15	is	be	AUX
admet-442	203	16	still	still	ADV
admet-442	203	17	limiting	limit	VERB
admet-442	203	18	and	and	CCONJ
admet-442	203	19	,	,	PUNCT
admet-442	203	20	more	more	ADJ
admet-442	203	21	studies	study	NOUN
admet-442	203	22	are	be	AUX
admet-442	203	23	needed	need	VERB
admet-442	203	24	to	to	PART
admet-442	203	25	get	get	VERB
admet-442	203	26	a	a	DET
admet-442	203	27	better	well	ADJ
admet-442	203	28	in	in	ADP
admet-442	203	29	the	the	DET
admet-442	203	30	regulation	regulation	NOUN
admet-442	203	31	of	of	ADP
admet-442	203	32	pd	pd	PROPN
admet-442	203	33	-	-	PROPN
admet-442	203	34	l1	l1	PROPN
admet-442	203	35	on	on	ADP
admet-442	203	36	cancer	cancer	NOUN
admet-442	203	37	.	.	PUNCT
admet-442	204	1	acknowledgements	acknowledgement	NOUN
admet-442	204	2	:	:	PUNCT
admet-442	204	3	this	this	DET
admet-442	204	4	work	work	NOUN
admet-442	204	5	was	be	AUX
admet-442	204	6	supported	support	VERB
admet-442	204	7	by	by	ADP
admet-442	204	8	the	the	DET
admet-442	204	9	science	science	NOUN
admet-442	204	10	and	and	CCONJ
admet-442	204	11	technology	technology	NOUN
admet-442	204	12	development	development	NOUN
admet-442	204	13	fund	fund	NOUN
admet-442	204	14	of	of	ADP
admet-442	204	15	macau	macau	PROPN
admet-442	204	16	sar	sar	PROPN
admet-442	204	17	(	(	PUNCT
admet-442	204	18	fdct	fdct	PROPN
admet-442	204	19	)	)	PUNCT
admet-442	205	1	[	[	X
admet-442	205	2	023/2015	023/2015	NUM
admet-442	205	3	/	/	SYM
admet-442	205	4	amj	amj	NOUN
admet-442	205	5	]	]	PUNCT
admet-442	205	6	and	and	CCONJ
admet-442	205	7	the	the	DET
admet-442	205	8	international	international	ADJ
admet-442	205	9	s&t	s&t	PROPN
admet-442	205	10	cooperation	cooperation	NOUN
admet-442	205	11	program	program	NOUN
admet-442	205	12	of	of	ADP
admet-442	205	13	china	china	PROPN
admet-442	206	1	[	[	X
admet-442	206	2	2016yfe0121900	2016yfe0121900	NUM
admet-442	206	3	]	]	PUNCT
admet-442	206	4	.	.	PUNCT
admet-442	207	1	miss	miss	PROPN
admet-442	207	2	libin	libin	PROPN
admet-442	207	3	guo	guo	PROPN
admet-442	207	4	was	be	AUX
admet-442	207	5	in	in	ADP
admet-442	207	6	receipt	receipt	NOUN
admet-442	207	7	of	of	ADP
admet-442	207	8	phd	phd	NOUN
admet-442	207	9	studentship	studentship	NOUN
admet-442	207	10	from	from	ADP
admet-442	207	11	the	the	DET
admet-442	207	12	faculty	faculty	NOUN
admet-442	207	13	health	health	PROPN
admet-442	207	14	sciences	sciences	PROPN
admet-442	207	15	university	university	PROPN
admet-442	207	16	of	of	ADP
admet-442	207	17	macau	macau	PROPN
admet-442	207	18	and	and	CCONJ
admet-442	207	19	fdct	fdct	PROPN
admet-442	207	20	.	.	PUNCT
admet-442	208	1	references	reference	NOUN
admet-442	208	2	[	[	X
admet-442	208	3	1	1	NUM
admet-442	208	4	]	]	PUNCT
admet-442	208	5	z.	z.	PROPN
admet-442	208	6	lian	lian	PROPN
admet-442	208	7	,	,	PUNCT
admet-442	208	8	y.	y.	PROPN
admet-442	208	9	xie	xie	PROPN
admet-442	208	10	,	,	PUNCT
admet-442	208	11	y.	y.	PROPN
admet-442	208	12	lu	lu	PROPN
admet-442	208	13	,	,	PUNCT
admet-442	208	14	d.	d.	PROPN
admet-442	208	15	huang	huang	PROPN
admet-442	208	16	,	,	PUNCT
admet-442	208	17	h.	h.	PROPN
admet-442	208	18	shi	shi	PROPN
admet-442	208	19	.	.	PUNCT
admet-442	209	1	trends	trend	NOUN
admet-442	209	2	in	in	ADP
admet-442	209	3	the	the	DET
admet-442	209	4	major	major	ADJ
admet-442	209	5	causes	cause	NOUN
admet-442	209	6	of	of	ADP
admet-442	209	7	death	death	NOUN
admet-442	209	8	in	in	ADP
admet-442	209	9	china	china	PROPN
admet-442	209	10	,	,	PUNCT
admet-442	209	11	1982	1982	NUM
admet-442	209	12	-	-	SYM
admet-442	209	13	2010	2010	NUM
admet-442	209	14	,	,	PUNCT
admet-442	209	15	chin	chin	PROPN
admet-442	209	16	med	med	PROPN
admet-442	209	17	j	j	PROPN
admet-442	209	18	(	(	PUNCT
admet-442	209	19	engl	engl	PROPN
admet-442	209	20	)	)	PUNCT
admet-442	209	21	127	127	NUM
admet-442	209	22	(	(	PUNCT
admet-442	209	23	2014	2014	NUM
admet-442	209	24	)	)	PUNCT
admet-442	209	25	777	777	NUM
admet-442	209	26	-	-	SYM
admet-442	209	27	781	781	NUM
admet-442	209	28	.	.	PUNCT
admet-442	210	1	[	[	X
admet-442	210	2	2	2	NUM
admet-442	210	3	]	]	X
admet-442	210	4	r.l	r.l	PROPN
admet-442	210	5	.	.	PROPN
admet-442	210	6	siegel	siegel	PROPN
admet-442	210	7	,	,	PUNCT
admet-442	210	8	k.d	k.d	PROPN
admet-442	210	9	.	.	PROPN
admet-442	210	10	miller	miller	PROPN
admet-442	210	11	,	,	PUNCT
admet-442	210	12	a.	a.	PROPN
admet-442	210	13	jemal	jemal	PROPN
admet-442	210	14	.	.	PUNCT
admet-442	211	1	cancer	cancer	NOUN
admet-442	211	2	statistics	statistic	NOUN
admet-442	211	3	,	,	PUNCT
admet-442	211	4	2017	2017	NUM
admet-442	211	5	,	,	PUNCT
admet-442	211	6	ca	can	AUX
admet-442	211	7	cancer	cancer	PROPN
admet-442	211	8	j	j	PROPN
admet-442	211	9	clin	clin	PROPN
admet-442	211	10	67	67	NUM
admet-442	211	11	(	(	PUNCT
admet-442	211	12	2017	2017	NUM
admet-442	211	13	)	)	PUNCT
admet-442	211	14	7	7	NUM
admet-442	211	15	-	-	SYM
admet-442	211	16	30	30	NUM
admet-442	211	17	.	.	PUNCT
admet-442	212	1	[	[	X
admet-442	212	2	3	3	X
admet-442	212	3	]	]	PUNCT
admet-442	212	4	l.	l.	PROPN
admet-442	212	5	yang	yang	PROPN
admet-442	212	6	,	,	PUNCT
admet-442	212	7	l.	l.	PROPN
admet-442	212	8	wang	wang	PROPN
admet-442	212	9	,	,	PUNCT
admet-442	212	10	y.	y.	PROPN
admet-442	212	11	zhang	zhang	PROPN
admet-442	212	12	.	.	PUNCT
admet-442	213	1	immunotherapy	immunotherapy	NOUN
admet-442	213	2	for	for	ADP
admet-442	213	3	lung	lung	NOUN
admet-442	213	4	cancer	cancer	NOUN
admet-442	213	5	:	:	PUNCT
admet-442	213	6	advances	advance	NOUN
admet-442	213	7	and	and	CCONJ
admet-442	213	8	prospects	prospect	NOUN
admet-442	213	9	,	,	PUNCT
admet-442	213	10	am	be	AUX
admet-442	213	11	j	j	PROPN
admet-442	213	12	clin	clin	PROPN
admet-442	213	13	exp	exp	PROPN
admet-442	213	14	immunol	immunol	NOUN
admet-442	213	15	5	5	NUM
admet-442	213	16	(	(	PUNCT
admet-442	213	17	2016	2016	NUM
admet-442	213	18	)	)	PUNCT
admet-442	213	19	1	1	NUM
admet-442	213	20	-	-	SYM
admet-442	213	21	20	20	NUM
admet-442	213	22	.	.	PUNCT
admet-442	214	1	[	[	X
admet-442	214	2	4	4	X
admet-442	214	3	]	]	X
admet-442	214	4	g.	g.	PROPN
admet-442	214	5	lezoche	lezoche	PROPN
admet-442	214	6	,	,	PUNCT
admet-442	214	7	a.m.	a.m.	PROPN
admet-442	214	8	paganini	paganini	PROPN
admet-442	214	9	,	,	PUNCT
admet-442	214	10	r.	r.	PROPN
admet-442	214	11	campagnacci	campagnacci	PROPN
admet-442	214	12	,	,	PUNCT
admet-442	214	13	r.	r.	PROPN
admet-442	214	14	ghiselli	ghiselli	PROPN
admet-442	214	15	,	,	PUNCT
admet-442	214	16	m.	m.	NOUN
admet-442	214	17	pelloni	pelloni	PROPN
admet-442	214	18	,	,	PUNCT
admet-442	214	19	a.	a.	NOUN
admet-442	214	20	rombini	rombini	NOUN
admet-442	214	21	,	,	PUNCT
admet-442	214	22	m.	m.	NOUN
admet-442	214	23	guerrieri	guerrieri	PROPN
admet-442	214	24	.	.	PUNCT
admet-442	215	1	treatment	treatment	NOUN
admet-442	215	2	of	of	ADP
admet-442	215	3	rectal	rectal	ADJ
admet-442	215	4	cancer	cancer	NOUN
admet-442	215	5	by	by	ADP
admet-442	215	6	transanal	transanal	ADJ
admet-442	215	7	endoscopic	endoscopic	ADJ
admet-442	215	8	microsurgery	microsurgery	NOUN
admet-442	215	9	:	:	PUNCT
admet-442	215	10	review	review	NOUN
admet-442	215	11	of	of	ADP
admet-442	215	12	the	the	DET
admet-442	215	13	literature	literature	NOUN
admet-442	215	14	,	,	PUNCT
admet-442	215	15	minerva	minerva	PROPN
admet-442	215	16	chir	chir	PROPN
admet-442	215	17	68	68	NUM
admet-442	215	18	(	(	PUNCT
admet-442	215	19	2013	2013	NUM
admet-442	215	20	)	)	PUNCT
admet-442	215	21	1	1	NUM
admet-442	215	22	-	-	SYM
admet-442	215	23	9	9	NUM
admet-442	215	24	.	.	PUNCT
admet-442	216	1	[	[	X
admet-442	216	2	5	5	NUM
admet-442	216	3	]	]	PUNCT
admet-442	216	4	a.	a.	NOUN
admet-442	216	5	munshi	munshi	PROPN
admet-442	216	6	,	,	PUNCT
admet-442	216	7	j.p	j.p	PROPN
admet-442	216	8	.	.	PROPN
admet-442	216	9	agarwal	agarwal	PROPN
admet-442	216	10	,	,	PUNCT
admet-442	216	11	k.c	k.c	PROPN
admet-442	216	12	.	.	PROPN
admet-442	216	13	pandey	pandey	PROPN
admet-442	216	14	.	.	PUNCT
admet-442	217	1	cancer	cancer	NOUN
admet-442	217	2	patients	patient	NOUN
admet-442	217	3	with	with	ADP
admet-442	217	4	cardiac	cardiac	ADJ
admet-442	217	5	pacemakers	pacemaker	NOUN
admet-442	217	6	needing	need	VERB
admet-442	217	7	radiation	radiation	NOUN
admet-442	217	8	treatment	treatment	NOUN
admet-442	217	9	:	:	PUNCT
admet-442	217	10	a	a	DET
admet-442	217	11	systematic	systematic	ADJ
admet-442	217	12	review	review	NOUN
admet-442	217	13	,	,	PUNCT
admet-442	217	14	j	j	PROPN
admet-442	217	15	cancer	cancer	NOUN
admet-442	217	16	res	re	NOUN
admet-442	217	17	ther	ther	ADV
admet-442	217	18	9	9	NUM
admet-442	217	19	(	(	PUNCT
admet-442	217	20	2013	2013	NUM
admet-442	217	21	)	)	PUNCT
admet-442	217	22	193	193	NUM
admet-442	217	23	-	-	SYM
admet-442	217	24	198	198	NUM
admet-442	217	25	.	.	PUNCT
admet-442	218	1	[	[	X
admet-442	218	2	6	6	NUM
admet-442	218	3	]	]	PUNCT
admet-442	218	4	m.	m.	NOUN
admet-442	218	5	johnson	johnson	PROPN
admet-442	218	6	.	.	PUNCT
admet-442	219	1	chemotherapy	chemotherapy	NOUN
admet-442	219	2	treatment	treatment	NOUN
admet-442	219	3	decision	decision	NOUN
admet-442	219	4	making	making	NOUN
admet-442	219	5	by	by	ADP
admet-442	219	6	professionals	professional	NOUN
admet-442	219	7	and	and	CCONJ
admet-442	219	8	older	old	ADJ
admet-442	219	9	patients	patient	NOUN
admet-442	219	10	with	with	ADP
admet-442	219	11	cancer	cancer	NOUN
admet-442	219	12	:	:	PUNCT
admet-442	219	13	a	a	DET
admet-442	219	14	narrative	narrative	ADJ
admet-442	219	15	review	review	NOUN
admet-442	219	16	of	of	ADP
admet-442	219	17	the	the	DET
admet-442	219	18	literature	literature	NOUN
admet-442	219	19	,	,	PUNCT
admet-442	219	20	eur	eur	PROPN
admet-442	219	21	j	j	PROPN
admet-442	219	22	cancer	cancer	NOUN
admet-442	219	23	care	care	NOUN
admet-442	219	24	(	(	PUNCT
admet-442	219	25	engl	engl	PROPN
admet-442	219	26	)	)	PUNCT
admet-442	219	27	21	21	NUM
admet-442	219	28	(	(	PUNCT
admet-442	219	29	2012	2012	NUM
admet-442	219	30	)	)	PUNCT
admet-442	219	31	3	3	NUM
admet-442	219	32	-	-	SYM
admet-442	219	33	9	9	NUM
admet-442	219	34	.	.	PUNCT
admet-442	220	1	[	[	X
admet-442	220	2	7	7	X
admet-442	220	3	]	]	X
admet-442	220	4	a.m.	a.m.	NOUN
admet-442	220	5	manganoni	manganoni	PROPN
admet-442	220	6	,	,	PUNCT
admet-442	220	7	c.	c.	PROPN
admet-442	220	8	zane	zane	PROPN
admet-442	220	9	,	,	PUNCT
admet-442	220	10	l.	l.	PROPN
admet-442	220	11	pavoni	pavoni	PROPN
admet-442	220	12	,	,	PUNCT
admet-442	220	13	c.	c.	PROPN
admet-442	220	14	farisoglio	farisoglio	PROPN
admet-442	220	15	,	,	PUNCT
admet-442	220	16	e.	e.	PROPN
admet-442	220	17	sereni	sereni	PROPN
admet-442	220	18	,	,	PUNCT
admet-442	220	19	p.	p.	PROPN
admet-442	220	20	calzavara	calzavara	PROPN
admet-442	220	21	-	-	PUNCT
admet-442	220	22	pinton	pinton	NOUN
admet-442	220	23	.	.	PUNCT
admet-442	221	1	cutaneous	cutaneous	ADJ
admet-442	221	2	melanoma	melanoma	NOUN
admet-442	221	3	in	in	ADP
admet-442	221	4	patients	patient	NOUN
admet-442	221	5	in	in	ADP
admet-442	221	6	treatment	treatment	NOUN
admet-442	221	7	with	with	ADP
admet-442	221	8	biological	biological	ADJ
admet-442	221	9	therapy	therapy	NOUN
admet-442	221	10	:	:	PUNCT
admet-442	221	11	review	review	NOUN
admet-442	221	12	of	of	ADP
admet-442	221	13	the	the	DET
admet-442	221	14	literature	literature	NOUN
admet-442	221	15	and	and	CCONJ
admet-442	221	16	case	case	NOUN
admet-442	221	17	report	report	NOUN
admet-442	221	18	,	,	PUNCT
admet-442	221	19	dermatol	dermatol	NOUN
admet-442	221	20	online	online	ADJ
admet-442	221	21	j	j	PROPN
admet-442	221	22	17	17	NUM
admet-442	221	23	(	(	PUNCT
admet-442	221	24	2011	2011	NUM
admet-442	221	25	)	)	PUNCT
admet-442	221	26	12	12	NUM
admet-442	221	27	.	.	PUNCT
admet-442	222	1	[	[	X
admet-442	222	2	8	8	NUM
admet-442	222	3	]	]	X
admet-442	222	4	m.	m.	NOUN
admet-442	222	5	kudo	kudo	PROPN
admet-442	222	6	.	.	PROPN
admet-442	222	7	targeted	target	VERB
admet-442	222	8	therapy	therapy	NOUN
admet-442	222	9	for	for	ADP
admet-442	222	10	liver	liver	NOUN
admet-442	222	11	cancer	cancer	NOUN
admet-442	222	12	:	:	PUNCT
admet-442	222	13	updated	update	VERB
admet-442	222	14	review	review	NOUN
admet-442	222	15	in	in	ADP
admet-442	222	16	2012	2012	NUM
admet-442	222	17	,	,	PUNCT
admet-442	222	18	curr	curr	PROPN
admet-442	222	19	cancer	cancer	NOUN
admet-442	222	20	drug	drug	NOUN
admet-442	222	21	targets	target	NOUN
admet-442	222	22	12	12	NUM
admet-442	222	23	(	(	PUNCT
admet-442	222	24	2012	2012	NUM
admet-442	222	25	)	)	PUNCT
admet-442	222	26	1062	1062	NUM
admet-442	222	27	-	-	SYM
admet-442	222	28	1072	1072	NUM
admet-442	222	29	.	.	PUNCT
admet-442	223	1	[	[	X
admet-442	223	2	9	9	NUM
admet-442	223	3	]	]	X
admet-442	223	4	d.g	d.g	PROPN
admet-442	223	5	.	.	PROPN
admet-442	223	6	maloney	maloney	PROPN
admet-442	223	7	,	,	PUNCT
admet-442	223	8	a.j	a.j	PROPN
admet-442	223	9	.	.	PROPN
admet-442	223	10	grillolopez	grillolopez	PROPN
admet-442	223	11	,	,	PUNCT
admet-442	223	12	c.a	c.a	PROPN
admet-442	223	13	.	.	PROPN
admet-442	223	14	white	white	PROPN
admet-442	223	15	,	,	PUNCT
admet-442	223	16	d.	d.	PROPN
admet-442	223	17	bodkin	bodkin	PROPN
admet-442	223	18	,	,	PUNCT
admet-442	223	19	r.j	r.j	PROPN
admet-442	223	20	.	.	PROPN
admet-442	223	21	schilder	schilder	PROPN
admet-442	223	22	,	,	PUNCT
admet-442	223	23	j.a	j.a	PROPN
admet-442	223	24	.	.	PROPN
admet-442	223	25	neidhart	neidhart	PROPN
admet-442	223	26	,	,	PUNCT
admet-442	223	27	n.	n.	PROPN
admet-442	223	28	janakiraman	janakiraman	PROPN
admet-442	223	29	,	,	PUNCT
admet-442	223	30	k.a	k.a	PROPN
admet-442	223	31	.	.	PROPN
admet-442	223	32	foon	foon	PROPN
admet-442	223	33	,	,	PUNCT
admet-442	223	34	t.m	t.m	PROPN
admet-442	223	35	.	.	PROPN
admet-442	223	36	liles	liles	PROPN
admet-442	223	37	,	,	PUNCT
admet-442	223	38	b.k	b.k	PROPN
admet-442	223	39	.	.	PROPN
admet-442	223	40	dallaire	dallaire	PROPN
admet-442	223	41	,	,	PUNCT
admet-442	223	42	k.	k.	PROPN
admet-442	223	43	wey	wey	PROPN
admet-442	223	44	,	,	PUNCT
admet-442	223	45	i.	i.	PROPN
admet-442	223	46	royston	royston	PROPN
admet-442	223	47	,	,	PUNCT
admet-442	223	48	t.	t.	PROPN
admet-442	223	49	davis	davis	PROPN
admet-442	223	50	,	,	PUNCT
admet-442	223	51	r.	r.	PROPN
admet-442	223	52	levy	levy	PROPN
admet-442	223	53	.	.	PUNCT
admet-442	224	1	idec	idec	PROPN
admet-442	224	2	-	-	PUNCT
admet-442	224	3	c2b8	c2b8	PROPN
admet-442	224	4	(	(	PUNCT
admet-442	224	5	rituximab	rituximab	NOUN
admet-442	224	6	)	)	PUNCT
admet-442	224	7	anticd20	anticd20	NOUN
admet-442	224	8	monoclonal	monoclonal	NOUN
admet-442	224	9	antibody	antibody	NOUN
admet-442	224	10	therapy	therapy	NOUN
admet-442	224	11	in	in	ADP
admet-442	224	12	patients	patient	NOUN
admet-442	224	13	with	with	ADP
admet-442	224	14	relapsed	relapse	VERB
admet-442	224	15	low	low	ADJ
admet-442	224	16	-	-	PUNCT
admet-442	224	17	grade	grade	NOUN
admet-442	224	18	non	non	ADJ
admet-442	224	19	-	-	ADJ
admet-442	224	20	hodgkin	hodgkin	NOUN
admet-442	224	21	's	's	PART
admet-442	224	22	lymphoma	lymphoma	NOUN
admet-442	224	23	,	,	PUNCT
admet-442	224	24	blood	blood	NOUN
admet-442	224	25	90	90	NUM
admet-442	224	26	(	(	PUNCT
admet-442	224	27	1997	1997	NUM
admet-442	224	28	)	)	PUNCT
admet-442	224	29	2188	2188	NUM
admet-442	224	30	-	-	SYM
admet-442	224	31	2195	2195	NUM
admet-442	224	32	.	.	PUNCT
admet-442	225	1	[	[	X
admet-442	225	2	10	10	NUM
admet-442	225	3	]	]	X
admet-442	225	4	i.	i.	NOUN
admet-442	225	5	mellman	mellman	PROPN
admet-442	225	6	,	,	PUNCT
admet-442	225	7	g.	g.	PROPN
admet-442	225	8	coukos	coukos	PROPN
admet-442	225	9	,	,	PUNCT
admet-442	225	10	g.	g.	PROPN
admet-442	225	11	dranoff	dranoff	PROPN
admet-442	225	12	.	.	PUNCT
admet-442	226	1	cancer	cancer	NOUN
admet-442	226	2	immunotherapy	immunotherapy	NOUN
admet-442	226	3	comes	come	VERB
admet-442	226	4	of	of	ADP
admet-442	226	5	age	age	NOUN
admet-442	226	6	,	,	PUNCT
admet-442	226	7	nature	nature	NOUN
admet-442	226	8	480	480	NUM
admet-442	226	9	(	(	PUNCT
admet-442	226	10	2011	2011	NUM
admet-442	226	11	)	)	PUNCT
admet-442	226	12	480489	480489	NUM
admet-442	226	13	.	.	PUNCT
admet-442	227	1	[	[	X
admet-442	227	2	11	11	NUM
admet-442	227	3	]	]	X
admet-442	227	4	c.	c.	PROPN
admet-442	227	5	guo	guo	PROPN
admet-442	227	6	,	,	PUNCT
admet-442	227	7	m.h	m.h	PROPN
admet-442	227	8	.	.	PROPN
admet-442	227	9	manjili	manjili	PROPN
admet-442	227	10	,	,	PUNCT
admet-442	227	11	j.r	j.r	PROPN
admet-442	227	12	.	.	PROPN
admet-442	227	13	subjeck	subjeck	PROPN
admet-442	227	14	,	,	PUNCT
admet-442	227	15	d.	d.	PROPN
admet-442	227	16	sarkar	sarkar	PROPN
admet-442	227	17	,	,	PUNCT
admet-442	227	18	p.b	p.b	PROPN
admet-442	227	19	.	.	PROPN
admet-442	227	20	fisher	fisher	PROPN
admet-442	227	21	,	,	PUNCT
admet-442	227	22	x.y	x.y	PROPN
admet-442	227	23	.	.	PROPN
admet-442	227	24	wang	wang	PROPN
admet-442	227	25	.	.	PUNCT
admet-442	228	1	therapeutic	therapeutic	ADJ
admet-442	228	2	cancer	cancer	NOUN
admet-442	228	3	vaccines	vaccine	NOUN
admet-442	228	4	:	:	PUNCT
admet-442	228	5	past	past	ADJ
admet-442	228	6	,	,	PUNCT
admet-442	228	7	present	present	ADJ
admet-442	228	8	,	,	PUNCT
admet-442	228	9	and	and	CCONJ
admet-442	228	10	future	future	NOUN
admet-442	228	11	,	,	PUNCT
admet-442	228	12	adv	adv	PROPN
admet-442	228	13	cancer	cancer	NOUN
admet-442	228	14	res	re	VERB
admet-442	228	15	119	119	NUM
admet-442	228	16	(	(	PUNCT
admet-442	228	17	2013	2013	NUM
admet-442	228	18	)	)	PUNCT
admet-442	228	19	421	421	NUM
admet-442	228	20	-	-	SYM
admet-442	228	21	475	475	NUM
admet-442	228	22	.	.	PUNCT
admet-442	229	1	[	[	X
admet-442	229	2	12	12	NUM
admet-442	229	3	]	]	PUNCT
admet-442	229	4	m.	m.	NOUN
admet-442	229	5	themeli	themeli	NOUN
admet-442	229	6	,	,	PUNCT
admet-442	229	7	i.	i.	PROPN
admet-442	229	8	riviere	riviere	PROPN
admet-442	229	9	,	,	PUNCT
admet-442	229	10	m.	m.	NOUN
admet-442	229	11	sadelain	sadelain	PROPN
admet-442	229	12	.	.	PUNCT
admet-442	230	1	new	new	ADJ
admet-442	230	2	cell	cell	NOUN
admet-442	230	3	sources	source	NOUN
admet-442	230	4	for	for	ADP
admet-442	230	5	t	t	NOUN
admet-442	230	6	cell	cell	NOUN
admet-442	230	7	engineering	engineering	NOUN
admet-442	230	8	and	and	CCONJ
admet-442	230	9	adoptive	adoptive	ADJ
admet-442	230	10	immunotherapy	immunotherapy	NOUN
admet-442	230	11	,	,	PUNCT
admet-442	230	12	cell	cell	NOUN
admet-442	230	13	stem	stem	NOUN
admet-442	230	14	cell	cell	NOUN
admet-442	230	15	16	16	NUM
admet-442	230	16	(	(	PUNCT
admet-442	230	17	2015	2015	NUM
admet-442	230	18	)	)	PUNCT
admet-442	230	19	357	357	NUM
admet-442	230	20	-	-	SYM
admet-442	230	21	366	366	NUM
admet-442	230	22	.	.	PUNCT
admet-442	231	1	[	[	X
admet-442	231	2	13	13	NUM
admet-442	231	3	]	]	X
admet-442	231	4	s.j	s.j	PROPN
admet-442	231	5	.	.	PROPN
admet-442	231	6	russell	russell	PROPN
admet-442	231	7	,	,	PUNCT
admet-442	231	8	k.w	k.w	PROPN
admet-442	231	9	.	.	PROPN
admet-442	231	10	peng	peng	PROPN
admet-442	231	11	,	,	PUNCT
admet-442	231	12	j.c	j.c	PROPN
admet-442	231	13	.	.	PROPN
admet-442	231	14	bell	bell	PROPN
admet-442	231	15	.	.	PUNCT
admet-442	232	1	oncolytic	oncolytic	PROPN
admet-442	232	2	virotherapy	virotherapy	PROPN
admet-442	232	3	,	,	PUNCT
admet-442	232	4	nat	nat	PROPN
admet-442	232	5	biotechnol	biotechnol	NOUN
admet-442	232	6	30	30	NUM
admet-442	232	7	(	(	PUNCT
admet-442	232	8	2012	2012	NUM
admet-442	232	9	)	)	PUNCT
admet-442	232	10	658	658	NUM
admet-442	232	11	-	-	SYM
admet-442	232	12	670	670	NUM
admet-442	232	13	.	.	PUNCT
admet-442	233	1	[	[	X
admet-442	233	2	14	14	NUM
admet-442	233	3	]	]	X
admet-442	233	4	l.	l.	PROPN
admet-442	233	5	galluzzi	galluzzi	PROPN
admet-442	233	6	,	,	PUNCT
admet-442	233	7	e.	e.	PROPN
admet-442	233	8	vacchelli	vacchelli	PROPN
admet-442	233	9	,	,	PUNCT
admet-442	233	10	j.m	j.m	PROPN
admet-442	233	11	.	.	PROPN
admet-442	233	12	bravo	bravo	PROPN
admet-442	233	13	-	-	PUNCT
admet-442	233	14	san	san	PROPN
admet-442	233	15	pedro	pedro	PROPN
admet-442	233	16	,	,	PUNCT
admet-442	233	17	a.	a.	NOUN
admet-442	233	18	buque	buque	NOUN
admet-442	233	19	,	,	PUNCT
admet-442	233	20	l.	l.	PROPN
admet-442	233	21	senovilla	senovilla	PROPN
admet-442	233	22	,	,	PUNCT
admet-442	233	23	e.e	e.e	PROPN
admet-442	233	24	.	.	PROPN
admet-442	233	25	baracco	baracco	PROPN
admet-442	233	26	,	,	PUNCT
admet-442	233	27	n.	n.	PROPN
admet-442	233	28	bloy	bloy	PROPN
admet-442	233	29	,	,	PUNCT
admet-442	233	30	f.	f.	PROPN
admet-442	233	31	castoldi	castoldi	PROPN
admet-442	233	32	,	,	PUNCT
admet-442	233	33	j.p	j.p	PROPN
admet-442	233	34	.	.	PROPN
admet-442	233	35	abastado	abastado	PROPN
admet-442	233	36	,	,	PUNCT
admet-442	233	37	p.	p.	PROPN
admet-442	233	38	agostinis	agostinis	PROPN
admet-442	233	39	,	,	PUNCT
admet-442	233	40	r.n	r.n	PROPN
admet-442	233	41	.	.	PROPN
admet-442	233	42	apte	apte	PROPN
admet-442	233	43	,	,	PUNCT
admet-442	233	44	f.	f.	PROPN
admet-442	233	45	aranda	aranda	PROPN
admet-442	233	46	,	,	PUNCT
admet-442	233	47	m.	m.	NOUN
admet-442	233	48	ayyoub	ayyoub	PROPN
admet-442	233	49	,	,	PUNCT
admet-442	233	50	p.	p.	PROPN
admet-442	233	51	beckhove	beckhove	NOUN
admet-442	233	52	,	,	PUNCT
admet-442	233	53	j.y	j.y	PROPN
admet-442	233	54	.	.	PROPN
admet-442	233	55	blay	blay	PROPN
admet-442	233	56	,	,	PUNCT
admet-442	233	57	l.	l.	PROPN
admet-442	233	58	bracci	bracci	PROPN
admet-442	233	59	,	,	PUNCT
admet-442	233	60	a.	a.	NOUN
admet-442	233	61	caignard	caignard	PROPN
admet-442	233	62	,	,	PUNCT
admet-442	233	63	c.	c.	PROPN
admet-442	233	64	castelli	castelli	PROPN
admet-442	233	65	,	,	PUNCT
admet-442	233	66	f.	f.	PROPN
admet-442	233	67	cavallo	cavallo	PROPN
admet-442	233	68	,	,	PUNCT
admet-442	233	69	e.	e.	PROPN
admet-442	233	70	celis	celis	PROPN
admet-442	233	71	,	,	PUNCT
admet-442	233	72	v.	v.	PROPN
admet-442	233	73	cerundolo	cerundolo	PROPN
admet-442	233	74	,	,	PUNCT
admet-442	233	75	a.	a.	PROPN
admet-442	233	76	clayton	clayton	PROPN
admet-442	233	77	,	,	PUNCT
admet-442	233	78	m.p	m.p	PROPN
admet-442	233	79	.	.	PROPN
admet-442	233	80	colombo	colombo	PROPN
admet-442	233	81	,	,	PUNCT
admet-442	233	82	l.	l.	PROPN
admet-442	233	83	coussens	coussens	PROPN
admet-442	233	84	,	,	PUNCT
admet-442	233	85	m.v	m.v	PROPN
admet-442	233	86	.	.	PROPN
admet-442	233	87	dhodapkar	dhodapkar	PROPN
admet-442	233	88	,	,	PUNCT
admet-442	233	89	a.m.	a.m.	NOUN
admet-442	233	90	eggermont	eggermont	PROPN
admet-442	233	91	,	,	PUNCT
admet-442	233	92	d.t	d.t	PROPN
admet-442	233	93	.	.	PROPN
admet-442	233	94	fearon	fearon	PROPN
admet-442	233	95	,	,	PUNCT
admet-442	233	96	w.h	w.h	PROPN
admet-442	233	97	.	.	PROPN
admet-442	233	98	fridman	fridman	PROPN
admet-442	233	99	,	,	PUNCT
admet-442	233	100	j.	j.	PROPN
admet-442	233	101	fucikova	fucikova	PROPN
admet-442	233	102	,	,	PUNCT
admet-442	233	103	d.i	d.i	PROPN
admet-442	233	104	.	.	PROPN
admet-442	233	105	gabrilovich	gabrilovich	PROPN
admet-442	233	106	,	,	PUNCT
admet-442	233	107	j.	j.	PROPN
admet-442	233	108	galon	galon	PROPN
admet-442	233	109	,	,	PUNCT
admet-442	233	110	a.	a.	NOUN
admet-442	233	111	garg	garg	PROPN
admet-442	233	112	,	,	PUNCT
admet-442	233	113	f.	f.	PROPN
admet-442	233	114	ghiringhelli	ghiringhelli	PROPN
admet-442	233	115	,	,	PUNCT
admet-442	233	116	g.	g.	PROPN
admet-442	233	117	giaccone	giaccone	PROPN
admet-442	233	118	,	,	PUNCT
admet-442	233	119	e.	e.	PROPN
admet-442	233	120	gilboa	gilboa	PROPN
admet-442	233	121	,	,	PUNCT
admet-442	233	122	s.	s.	PROPN
admet-442	233	123	gnjatic	gnjatic	PROPN
admet-442	233	124	,	,	PUNCT
admet-442	233	125	a.	a.	NOUN
admet-442	233	126	hoos	hoos	PROPN
admet-442	233	127	,	,	PUNCT
admet-442	233	128	a.	a.	PROPN
admet-442	233	129	admet	admet	PROPN
admet-442	233	130	&	&	CCONJ
admet-442	233	131	dmpk	dmpk	PROPN
admet-442	233	132	5(3	5(3	NUM
admet-442	233	133	)	)	PUNCT
admet-442	233	134	(	(	PUNCT
admet-442	233	135	2017	2017	NUM
admet-442	233	136	)	)	PUNCT
admet-442	233	137	159	159	NUM
admet-442	233	138	-	-	SYM
admet-442	233	139	172	172	NUM
admet-442	233	140	the	the	DET
admet-442	233	141	function	function	NOUN
admet-442	233	142	and	and	CCONJ
admet-442	233	143	regulation	regulation	NOUN
admet-442	233	144	of	of	ADP
admet-442	233	145	pd	pd	PROPN
admet-442	233	146	-	-	PROPN
admet-442	233	147	l1	l1	PROPN
admet-442	233	148	in	in	ADP
admet-442	233	149	immunotherapy	immunotherapy	NOUN
admet-442	233	150	doi	doi	NOUN
admet-442	233	151	:	:	PUNCT
admet-442	233	152	10.5599	10.5599	NUM
admet-442	233	153	/	/	SYM
admet-442	233	154	admet.5.3.442	admet.5.3.442	NUM
admet-442	233	155	167	167	NUM
admet-442	233	156	hosmalin	hosmalin	NOUN
admet-442	233	157	,	,	PUNCT
admet-442	233	158	d.	d.	PROPN
admet-442	233	159	jager	jager	PROPN
admet-442	233	160	,	,	PUNCT
admet-442	233	161	p.	p.	PROPN
admet-442	233	162	kalinski	kalinski	PROPN
admet-442	233	163	,	,	PUNCT
admet-442	233	164	k.	k.	PROPN
admet-442	233	165	karre	karre	PROPN
admet-442	233	166	,	,	PUNCT
admet-442	233	167	o.	o.	PROPN
admet-442	233	168	kepp	kepp	PROPN
admet-442	233	169	,	,	PUNCT
admet-442	233	170	r.	r.	PROPN
admet-442	233	171	kiessling	kiessling	PROPN
admet-442	233	172	,	,	PUNCT
admet-442	233	173	j.m	j.m	PROPN
admet-442	233	174	.	.	PROPN
admet-442	233	175	kirkwood	kirkwood	PROPN
admet-442	233	176	,	,	PUNCT
admet-442	233	177	e.	e.	PROPN
admet-442	233	178	klein	klein	PROPN
admet-442	233	179	,	,	PUNCT
admet-442	233	180	a.	a.	PROPN
admet-442	233	181	knuth	knuth	PROPN
admet-442	233	182	,	,	PUNCT
admet-442	233	183	c.e	c.e	PROPN
admet-442	233	184	.	.	PROPN
admet-442	233	185	lewis	lewis	PROPN
admet-442	233	186	,	,	PUNCT
admet-442	233	187	r.	r.	PROPN
admet-442	233	188	liblau	liblau	PROPN
admet-442	233	189	,	,	PUNCT
admet-442	233	190	m.t	m.t	PROPN
admet-442	233	191	.	.	PROPN
admet-442	233	192	lotze	lotze	PROPN
admet-442	233	193	,	,	PUNCT
admet-442	233	194	e.	e.	PROPN
admet-442	233	195	lugli	lugli	PROPN
admet-442	233	196	,	,	PUNCT
admet-442	233	197	j.p	j.p	PROPN
admet-442	233	198	.	.	PROPN
admet-442	233	199	mach	mach	PROPN
admet-442	233	200	,	,	PUNCT
admet-442	233	201	f.	f.	PROPN
admet-442	233	202	mattei	mattei	PROPN
admet-442	233	203	,	,	PUNCT
admet-442	233	204	d.	d.	PROPN
admet-442	233	205	mavilio	mavilio	PROPN
admet-442	233	206	,	,	PUNCT
admet-442	233	207	i.	i.	PROPN
admet-442	233	208	melero	melero	PROPN
admet-442	233	209	,	,	PUNCT
admet-442	233	210	c.j	c.j	PROPN
admet-442	233	211	.	.	PROPN
admet-442	233	212	melief	melief	PROPN
admet-442	233	213	,	,	PUNCT
admet-442	233	214	e.a	e.a	PROPN
admet-442	233	215	.	.	PROPN
admet-442	233	216	mittendorf	mittendorf	PROPN
admet-442	233	217	,	,	PUNCT
admet-442	233	218	l.	l.	PROPN
admet-442	233	219	moretta	moretta	PROPN
admet-442	233	220	,	,	PUNCT
admet-442	233	221	a.	a.	NOUN
admet-442	233	222	odunsi	odunsi	PROPN
admet-442	233	223	,	,	PUNCT
admet-442	233	224	h.	h.	PROPN
admet-442	233	225	okada	okada	PROPN
admet-442	233	226	,	,	PUNCT
admet-442	233	227	a.k	a.k	PROPN
admet-442	233	228	.	.	PROPN
admet-442	233	229	palucka	palucka	PROPN
admet-442	233	230	,	,	PUNCT
admet-442	233	231	m.e	m.e	PROPN
admet-442	233	232	.	.	PROPN
admet-442	233	233	peter	peter	PROPN
admet-442	233	234	,	,	PUNCT
admet-442	233	235	k.j	k.j	PROPN
admet-442	233	236	.	.	PROPN
admet-442	233	237	pienta	pienta	PROPN
admet-442	233	238	,	,	PUNCT
admet-442	233	239	a.	a.	NOUN
admet-442	233	240	porgador	porgador	PROPN
admet-442	233	241	,	,	PUNCT
admet-442	233	242	g.c	g.c	PROPN
admet-442	233	243	.	.	PROPN
admet-442	233	244	prendergast	prendergast	PROPN
admet-442	233	245	,	,	PUNCT
admet-442	233	246	g.a	g.a	PROPN
admet-442	233	247	.	.	PROPN
admet-442	233	248	rabinovich	rabinovich	PROPN
admet-442	233	249	,	,	PUNCT
admet-442	233	250	n.p	n.p	PROPN
admet-442	233	251	.	.	PROPN
admet-442	233	252	restifo	restifo	PROPN
admet-442	233	253	,	,	PUNCT
admet-442	233	254	n.	n.	NOUN
admet-442	233	255	rizvi	rizvi	PROPN
admet-442	233	256	,	,	PUNCT
admet-442	233	257	c.	c.	PROPN
admet-442	233	258	sautes	saute	NOUN
admet-442	233	259	-	-	PUNCT
admet-442	233	260	fridman	fridman	ADJ
admet-442	233	261	,	,	PUNCT
admet-442	233	262	h.	h.	PROPN
admet-442	233	263	schreiber	schreiber	PROPN
admet-442	233	264	,	,	PUNCT
admet-442	233	265	b.	b.	PROPN
admet-442	233	266	seliger	seliger	PROPN
admet-442	233	267	,	,	PUNCT
admet-442	233	268	h.	h.	PROPN
admet-442	233	269	shiku	shiku	PROPN
admet-442	233	270	,	,	PUNCT
admet-442	233	271	b.	b.	PROPN
admet-442	233	272	silva	silva	PROPN
admet-442	233	273	-	-	PUNCT
admet-442	233	274	santos	santos	PROPN
admet-442	233	275	,	,	PUNCT
admet-442	233	276	m.j	m.j	PROPN
admet-442	233	277	.	.	PROPN
admet-442	233	278	smyth	smyth	PROPN
admet-442	233	279	,	,	PUNCT
admet-442	233	280	d.e	d.e	PROPN
admet-442	233	281	.	.	PROPN
admet-442	233	282	speiser	speiser	PROPN
admet-442	233	283	,	,	PUNCT
admet-442	233	284	r.	r.	PROPN
admet-442	233	285	spisek	spisek	PROPN
admet-442	233	286	,	,	PUNCT
admet-442	233	287	p.k	p.k	PROPN
admet-442	233	288	.	.	PROPN
admet-442	233	289	srivastava	srivastava	PROPN
admet-442	233	290	,	,	PUNCT
admet-442	233	291	j.e	j.e	PROPN
admet-442	233	292	.	.	PROPN
admet-442	233	293	talmadge	talmadge	PROPN
admet-442	233	294	,	,	PUNCT
admet-442	233	295	e.	e.	PROPN
admet-442	233	296	tartour	tartour	PROPN
admet-442	233	297	,	,	PUNCT
admet-442	233	298	s.h	s.h	PROPN
admet-442	233	299	.	.	PROPN
admet-442	233	300	van	van	PROPN
admet-442	233	301	der	der	PROPN
admet-442	233	302	burg	burg	PROPN
admet-442	233	303	,	,	PUNCT
admet-442	233	304	b.j	b.j	PROPN
admet-442	233	305	.	.	PROPN
admet-442	233	306	van	van	PROPN
admet-442	233	307	den	den	PROPN
admet-442	233	308	eynde	eynde	PROPN
admet-442	233	309	,	,	PUNCT
admet-442	233	310	r.	r.	PROPN
admet-442	233	311	vile	vile	PROPN
admet-442	233	312	,	,	PUNCT
admet-442	233	313	h.	h.	PROPN
admet-442	233	314	wagner	wagner	PROPN
admet-442	233	315	,	,	PUNCT
admet-442	233	316	j.s	j.s	PROPN
admet-442	233	317	.	.	PROPN
admet-442	233	318	weber	weber	PROPN
admet-442	233	319	,	,	PUNCT
admet-442	233	320	t.l	t.l	PROPN
admet-442	233	321	.	.	PROPN
admet-442	233	322	whiteside	whiteside	PROPN
admet-442	233	323	,	,	PUNCT
admet-442	233	324	j.d	j.d	PROPN
admet-442	233	325	.	.	PROPN
admet-442	233	326	wolchok	wolchok	PROPN
admet-442	233	327	,	,	PUNCT
admet-442	233	328	l.	l.	PROPN
admet-442	233	329	zitvogel	zitvogel	PROPN
admet-442	233	330	,	,	PUNCT
admet-442	233	331	w.	w.	PROPN
admet-442	233	332	zou	zou	PROPN
admet-442	233	333	,	,	PUNCT
admet-442	233	334	g.	g.	PROPN
admet-442	233	335	kroemer	kroemer	PROPN
admet-442	233	336	.	.	PUNCT
admet-442	234	1	classification	classification	NOUN
admet-442	234	2	of	of	ADP
admet-442	234	3	current	current	ADJ
admet-442	234	4	anticancer	anticancer	NOUN
admet-442	234	5	immunotherapies	immunotherapy	NOUN
admet-442	234	6	,	,	PUNCT
admet-442	234	7	oncotarget	oncotarget	VERB
admet-442	234	8	5	5	NUM
admet-442	234	9	(	(	PUNCT
admet-442	234	10	2014	2014	NUM
admet-442	234	11	)	)	PUNCT
admet-442	234	12	12472	12472	NUM
admet-442	234	13	-	-	SYM
admet-442	234	14	12508	12508	NUM
admet-442	234	15	.	.	PUNCT
admet-442	235	1	[	[	X
admet-442	235	2	15	15	NUM
admet-442	235	3	]	]	X
admet-442	235	4	s.	s.	PROPN
admet-442	235	5	carvalho	carvalho	PROPN
admet-442	235	6	,	,	PUNCT
admet-442	235	7	f.	f.	PROPN
admet-442	235	8	levi	levi	PROPN
admet-442	235	9	-	-	PUNCT
admet-442	235	10	schaffer	schaffer	PROPN
admet-442	235	11	,	,	PUNCT
admet-442	235	12	m.	m.	NOUN
admet-442	235	13	sela	sela	PROPN
admet-442	235	14	,	,	PUNCT
admet-442	235	15	y.	y.	PROPN
admet-442	235	16	yarden	yarden	PROPN
admet-442	235	17	.	.	PUNCT
admet-442	236	1	immunotherapy	immunotherapy	NOUN
admet-442	236	2	of	of	ADP
admet-442	236	3	cancer	cancer	NOUN
admet-442	236	4	:	:	PUNCT
admet-442	236	5	from	from	ADP
admet-442	236	6	monoclonal	monoclonal	NOUN
admet-442	236	7	to	to	ADP
admet-442	236	8	oligoclonal	oligoclonal	ADJ
admet-442	236	9	cocktails	cocktail	NOUN
admet-442	236	10	of	of	ADP
admet-442	236	11	anti	anti	ADJ
admet-442	236	12	-	-	ADJ
admet-442	236	13	cancer	cancer	ADJ
admet-442	236	14	antibodies	antibodie	VERB
admet-442	236	15	:	:	PUNCT
admet-442	236	16	iuphar	iuphar	PROPN
admet-442	236	17	review	review	PROPN
admet-442	236	18	18	18	NUM
admet-442	236	19	,	,	PUNCT
admet-442	236	20	brit	brit	PROPN
admet-442	236	21	j	j	PROPN
admet-442	236	22	pharmacol	pharmacol	PROPN
admet-442	236	23	173	173	NUM
admet-442	236	24	(	(	PUNCT
admet-442	236	25	2016	2016	NUM
admet-442	236	26	)	)	PUNCT
admet-442	236	27	1407	1407	NUM
admet-442	236	28	-	-	SYM
admet-442	236	29	1424	1424	NUM
admet-442	236	30	.	.	PUNCT
admet-442	237	1	[	[	X
admet-442	237	2	16	16	NUM
admet-442	237	3	]	]	X
admet-442	237	4	r.g	r.g	PROPN
admet-442	237	5	.	.	PROPN
admet-442	237	6	amado	amado	PROPN
admet-442	237	7	,	,	PUNCT
admet-442	237	8	m.	m.	NOUN
admet-442	237	9	wolf	wolf	PROPN
admet-442	237	10	,	,	PUNCT
admet-442	237	11	m.	m.	NOUN
admet-442	237	12	peeters	peeter	NOUN
admet-442	237	13	,	,	PUNCT
admet-442	237	14	e.	e.	PROPN
admet-442	237	15	van	van	PROPN
admet-442	237	16	cutsem	cutsem	PROPN
admet-442	237	17	,	,	PUNCT
admet-442	237	18	s.	s.	PROPN
admet-442	237	19	siena	siena	PROPN
admet-442	237	20	,	,	PUNCT
admet-442	237	21	d.j	d.j	PROPN
admet-442	237	22	.	.	PROPN
admet-442	237	23	freeman	freeman	PROPN
admet-442	237	24	,	,	PUNCT
admet-442	237	25	t.	t.	PROPN
admet-442	237	26	juan	juan	PROPN
admet-442	237	27	,	,	PUNCT
admet-442	237	28	r.	r.	PROPN
admet-442	237	29	sikorski	sikorski	PROPN
admet-442	237	30	,	,	PUNCT
admet-442	237	31	s.	s.	PROPN
admet-442	237	32	suggs	suggs	PROPN
admet-442	237	33	,	,	PUNCT
admet-442	237	34	r.	r.	PROPN
admet-442	237	35	radinsky	radinsky	PROPN
admet-442	237	36	,	,	PUNCT
admet-442	237	37	s.d	s.d	PROPN
admet-442	237	38	.	.	PROPN
admet-442	237	39	patterson	patterson	PROPN
admet-442	237	40	,	,	PUNCT
admet-442	237	41	d.d	d.d	PROPN
admet-442	237	42	.	.	PROPN
admet-442	237	43	chang	chang	PROPN
admet-442	237	44	.	.	PUNCT
admet-442	238	1	wild	wild	ADJ
admet-442	238	2	-	-	PUNCT
admet-442	238	3	type	type	NOUN
admet-442	238	4	kras	kra	NOUN
admet-442	238	5	is	be	AUX
admet-442	238	6	required	require	VERB
admet-442	238	7	for	for	ADP
admet-442	238	8	panitumumab	panitumumab	NOUN
admet-442	238	9	efficacy	efficacy	NOUN
admet-442	238	10	in	in	ADP
admet-442	238	11	patients	patient	NOUN
admet-442	238	12	with	with	ADP
admet-442	238	13	metastatic	metastatic	ADJ
admet-442	238	14	colorectal	colorectal	ADJ
admet-442	238	15	cancer	cancer	NOUN
admet-442	238	16	,	,	PUNCT
admet-442	238	17	j	j	PROPN
admet-442	238	18	clin	clin	PROPN
admet-442	238	19	oncol	oncol	PROPN
admet-442	238	20	26	26	NUM
admet-442	238	21	(	(	PUNCT
admet-442	238	22	2008	2008	NUM
admet-442	238	23	)	)	PUNCT
admet-442	238	24	1626	1626	NUM
admet-442	238	25	-	-	SYM
admet-442	238	26	1634	1634	NUM
admet-442	238	27	.	.	PUNCT
admet-442	239	1	[	[	X
admet-442	239	2	17	17	NUM
admet-442	239	3	]	]	X
admet-442	239	4	j.r	j.r	PROPN
admet-442	239	5	.	.	PROPN
admet-442	239	6	thompson	thompson	PROPN
admet-442	239	7	,	,	PUNCT
admet-442	239	8	s.p	s.p	PROPN
admet-442	239	9	.	.	PROPN
admet-442	239	10	menon	menon	PROPN
admet-442	239	11	,	,	PUNCT
admet-442	239	12	g.k	g.k	PROPN
admet-442	239	13	.	.	PROPN
admet-442	239	14	dy	dy	PROPN
admet-442	239	15	.	.	PUNCT
admet-442	239	16	tyrosine	tyrosine	PROPN
admet-442	239	17	kinase	kinase	VERB
admet-442	239	18	inhibitors	inhibitor	NOUN
admet-442	239	19	for	for	ADP
admet-442	239	20	egfr	egfr	ADJ
admet-442	239	21	-	-	PUNCT
admet-442	239	22	and	and	CCONJ
admet-442	239	23	alk	alk	ADV
admet-442	239	24	-	-	PUNCT
admet-442	239	25	mutated	mutate	VERB
admet-442	239	26	nonsmall	nonsmall	NOUN
admet-442	239	27	cell	cell	NOUN
admet-442	239	28	lung	lung	NOUN
admet-442	239	29	cancer	cancer	NOUN
admet-442	239	30	,	,	PUNCT
admet-442	239	31	admet	admet	NOUN
admet-442	239	32	and	and	CCONJ
admet-442	239	33	dmpk	dmpk	X
admet-442	239	34	4	4	NUM
admet-442	239	35	(	(	PUNCT
admet-442	239	36	2016	2016	NUM
admet-442	239	37	)	)	PUNCT
admet-442	239	38	186	186	NUM
admet-442	239	39	-	-	SYM
admet-442	239	40	211	211	NUM
admet-442	239	41	.	.	PUNCT
admet-442	240	1	[	[	X
admet-442	240	2	18	18	NUM
admet-442	240	3	]	]	X
admet-442	240	4	s.j	s.j	PROPN
admet-442	240	5	.	.	PROPN
admet-442	240	6	demarest	demarest	PROPN
admet-442	240	7	,	,	PUNCT
admet-442	240	8	k.	k.	PROPN
admet-442	240	9	hariharan	hariharan	PROPN
admet-442	240	10	,	,	PUNCT
admet-442	240	11	j.	j.	PROPN
admet-442	240	12	dong	dong	PROPN
admet-442	240	13	.	.	PUNCT
admet-442	241	1	emerging	emerge	VERB
admet-442	241	2	antibody	antibody	NOUN
admet-442	241	3	combinations	combination	NOUN
admet-442	241	4	in	in	ADP
admet-442	241	5	oncology	oncology	NOUN
admet-442	241	6	,	,	PUNCT
admet-442	241	7	mabs	mab	NOUN
admet-442	241	8	3	3	NUM
admet-442	241	9	(	(	PUNCT
admet-442	241	10	2011	2011	NUM
admet-442	241	11	)	)	PUNCT
admet-442	241	12	338	338	NUM
admet-442	241	13	-	-	SYM
admet-442	241	14	351	351	NUM
admet-442	241	15	.	.	PUNCT
admet-442	242	1	[	[	X
admet-442	242	2	19	19	NUM
admet-442	242	3	]	]	X
admet-442	242	4	e.a	e.a	PROPN
admet-442	242	5	.	.	PROPN
admet-442	242	6	hawkes	hawkes	PROPN
admet-442	242	7	,	,	PUNCT
admet-442	242	8	a.	a.	NOUN
admet-442	242	9	grigg	grigg	PROPN
admet-442	242	10	,	,	PUNCT
admet-442	242	11	g.	g.	PROPN
admet-442	242	12	chong	chong	PROPN
admet-442	242	13	.	.	PUNCT
admet-442	243	1	programmed	program	VERB
admet-442	243	2	cell	cell	NOUN
admet-442	243	3	death-1	death-1	NUM
admet-442	243	4	inhibition	inhibition	NOUN
admet-442	243	5	in	in	ADP
admet-442	243	6	lymphoma	lymphoma	NOUN
admet-442	243	7	,	,	PUNCT
admet-442	243	8	lancet	lancet	VERB
admet-442	243	9	oncol	oncol	ADJ
admet-442	243	10	16	16	NUM
admet-442	243	11	(	(	PUNCT
admet-442	243	12	2015	2015	NUM
admet-442	243	13	)	)	PUNCT
admet-442	243	14	e234	e234	PROPN
admet-442	243	15	-	-	PUNCT
admet-442	243	16	e245	e245	PROPN
admet-442	243	17	.	.	PUNCT
admet-442	244	1	[	[	X
admet-442	244	2	20	20	NUM
admet-442	244	3	]	]	PUNCT
admet-442	244	4	j.	j.	PROPN
admet-442	244	5	liu	liu	PROPN
admet-442	244	6	,	,	PUNCT
admet-442	244	7	a.	a.	NOUN
admet-442	244	8	hamrouni	hamrouni	PROPN
admet-442	244	9	,	,	PUNCT
admet-442	244	10	d.	d.	PROPN
admet-442	244	11	wolowiec	wolowiec	PROPN
admet-442	244	12	,	,	PUNCT
admet-442	244	13	v.	v.	PROPN
admet-442	244	14	coiteux	coiteux	PROPN
admet-442	244	15	,	,	PUNCT
admet-442	244	16	k.	k.	PROPN
admet-442	244	17	kuliczkowski	kuliczkowski	PROPN
admet-442	244	18	,	,	PUNCT
admet-442	244	19	d.	d.	PROPN
admet-442	244	20	hetuin	hetuin	PROPN
admet-442	244	21	,	,	PUNCT
admet-442	244	22	a.	a.	NOUN
admet-442	244	23	saudemont	saudemont	PROPN
admet-442	244	24	,	,	PUNCT
admet-442	244	25	b.	b.	PROPN
admet-442	244	26	quesnel	quesnel	PROPN
admet-442	244	27	.	.	PUNCT
admet-442	245	1	plasma	plasma	NOUN
admet-442	245	2	cells	cell	NOUN
admet-442	245	3	from	from	ADP
admet-442	245	4	multiple	multiple	ADJ
admet-442	245	5	myeloma	myeloma	NOUN
admet-442	245	6	patients	patient	NOUN
admet-442	245	7	express	express	VERB
admet-442	245	8	b7	b7	PROPN
admet-442	245	9	-	-	PUNCT
admet-442	245	10	h1	h1	PROPN
admet-442	245	11	(	(	PUNCT
admet-442	245	12	pd	pd	NOUN
admet-442	245	13	-	-	PUNCT
admet-442	245	14	l1	l1	NOUN
admet-442	245	15	)	)	PUNCT
admet-442	245	16	and	and	CCONJ
admet-442	245	17	increase	increase	VERB
admet-442	245	18	expression	expression	NOUN
admet-442	245	19	after	after	ADP
admet-442	245	20	stimulation	stimulation	NOUN
admet-442	245	21	with	with	ADP
admet-442	245	22	ifn-{gamma	ifn-{gamma	PROPN
admet-442	245	23	}	}	PUNCT
admet-442	245	24	and	and	CCONJ
admet-442	245	25	tlr	tlr	PROPN
admet-442	245	26	ligands	ligand	NOUN
admet-442	245	27	via	via	ADP
admet-442	245	28	a	a	DET
admet-442	245	29	myd88-	myd88-	PROPN
admet-442	245	30	,	,	PUNCT
admet-442	245	31	traf6-	traf6-	NOUN
admet-442	245	32	,	,	PUNCT
admet-442	245	33	and	and	CCONJ
admet-442	245	34	mek	mek	PROPN
admet-442	245	35	-	-	PUNCT
admet-442	245	36	dependent	dependent	ADJ
admet-442	245	37	pathway	pathway	NOUN
admet-442	245	38	,	,	PUNCT
admet-442	245	39	blood	blood	NOUN
admet-442	245	40	110	110	NUM
admet-442	245	41	(	(	PUNCT
admet-442	245	42	2007	2007	NUM
admet-442	245	43	)	)	PUNCT
admet-442	245	44	296	296	NUM
admet-442	245	45	-	-	SYM
admet-442	245	46	304	304	NUM
admet-442	245	47	.	.	PUNCT
admet-442	246	1	[	[	X
admet-442	246	2	21	21	NUM
admet-442	246	3	]	]	X
admet-442	246	4	j.f	j.f	PROPN
admet-442	246	5	.	.	PROPN
admet-442	246	6	jacobs	jacobs	PROPN
admet-442	246	7	,	,	PUNCT
admet-442	246	8	a.j	a.j	PROPN
admet-442	246	9	.	.	PROPN
admet-442	246	10	idema	idema	PROPN
admet-442	246	11	,	,	PUNCT
admet-442	246	12	k.f	k.f	PROPN
admet-442	246	13	.	.	PROPN
admet-442	246	14	bol	bol	PROPN
admet-442	246	15	,	,	PUNCT
admet-442	246	16	s.	s.	PROPN
admet-442	246	17	nierkens	nierkens	PROPN
admet-442	246	18	,	,	PUNCT
admet-442	246	19	o.m	o.m	PROPN
admet-442	246	20	.	.	PROPN
admet-442	246	21	grauer	grauer	PROPN
admet-442	246	22	,	,	PUNCT
admet-442	246	23	p.	p.	NOUN
admet-442	246	24	wesseling	wesseling	NOUN
admet-442	246	25	,	,	PUNCT
admet-442	246	26	j.a	j.a	PROPN
admet-442	246	27	.	.	PROPN
admet-442	246	28	grotenhuis	grotenhuis	PROPN
admet-442	246	29	,	,	PUNCT
admet-442	246	30	p.m.	p.m.	NOUN
admet-442	246	31	hoogerbrugge	hoogerbrugge	ADV
admet-442	246	32	,	,	PUNCT
admet-442	246	33	i.j	i.j	PROPN
admet-442	246	34	.	.	PROPN
admet-442	246	35	de	de	PROPN
admet-442	246	36	vries	vries	PROPN
admet-442	246	37	,	,	PUNCT
admet-442	246	38	g.j	g.j	PROPN
admet-442	246	39	.	.	PROPN
admet-442	246	40	adema	adema	PROPN
admet-442	246	41	.	.	PUNCT
admet-442	247	1	regulatory	regulatory	ADJ
admet-442	247	2	t	t	NOUN
admet-442	247	3	cells	cell	NOUN
admet-442	247	4	and	and	CCONJ
admet-442	247	5	the	the	DET
admet-442	247	6	pd	pd	PROPN
admet-442	247	7	-	-	PUNCT
admet-442	247	8	l1	l1	PROPN
admet-442	247	9	/	/	SYM
admet-442	247	10	pd-1	pd-1	NOUN
admet-442	247	11	pathway	pathway	NOUN
admet-442	247	12	mediate	mediate	ADJ
admet-442	247	13	immune	immune	ADJ
admet-442	247	14	suppression	suppression	NOUN
admet-442	247	15	in	in	ADP
admet-442	247	16	malignant	malignant	ADJ
admet-442	247	17	human	human	ADJ
admet-442	247	18	brain	brain	NOUN
admet-442	247	19	tumors	tumor	NOUN
admet-442	247	20	,	,	PUNCT
admet-442	247	21	neuro	neuro	PROPN
admet-442	247	22	oncol	oncol	ADJ
admet-442	247	23	11	11	NUM
admet-442	247	24	(	(	PUNCT
admet-442	247	25	2009	2009	NUM
admet-442	247	26	)	)	PUNCT
admet-442	247	27	394	394	NUM
admet-442	247	28	-	-	SYM
admet-442	247	29	402	402	NUM
admet-442	247	30	.	.	PUNCT
admet-442	248	1	[	[	X
admet-442	248	2	22	22	NUM
admet-442	248	3	]	]	X
admet-442	248	4	a.t	a.t	PROPN
admet-442	248	5	.	.	PROPN
admet-442	248	6	parsa	parsa	PROPN
admet-442	248	7	,	,	PUNCT
admet-442	248	8	j.s	j.s	PROPN
admet-442	248	9	.	.	PROPN
admet-442	248	10	waldron	waldron	PROPN
admet-442	248	11	,	,	PUNCT
admet-442	248	12	a.	a.	PROPN
admet-442	248	13	panner	panner	PROPN
admet-442	248	14	,	,	PUNCT
admet-442	248	15	c.a	c.a	PROPN
admet-442	248	16	.	.	PROPN
admet-442	248	17	crane	crane	PROPN
admet-442	248	18	,	,	PUNCT
admet-442	248	19	i.f	i.f	PROPN
admet-442	248	20	.	.	PROPN
admet-442	248	21	parney	parney	NOUN
admet-442	248	22	,	,	PUNCT
admet-442	248	23	j.j	j.j	PROPN
admet-442	248	24	.	.	PROPN
admet-442	248	25	barry	barry	PROPN
admet-442	248	26	,	,	PUNCT
admet-442	248	27	k.e	k.e	PROPN
admet-442	248	28	.	.	PROPN
admet-442	248	29	cachola	cachola	PROPN
admet-442	248	30	,	,	PUNCT
admet-442	248	31	j.c	j.c	PROPN
admet-442	248	32	.	.	PROPN
admet-442	248	33	murray	murray	PROPN
admet-442	248	34	,	,	PUNCT
admet-442	248	35	t.	t.	PROPN
admet-442	248	36	tihan	tihan	PROPN
admet-442	248	37	,	,	PUNCT
admet-442	248	38	m.c	m.c	PROPN
admet-442	248	39	.	.	PROPN
admet-442	248	40	jensen	jensen	PROPN
admet-442	248	41	,	,	PUNCT
admet-442	248	42	p.s	p.s	PROPN
admet-442	248	43	.	.	PROPN
admet-442	248	44	mischel	mischel	PROPN
admet-442	248	45	,	,	PUNCT
admet-442	248	46	d.	d.	PROPN
admet-442	248	47	stokoe	stokoe	PROPN
admet-442	248	48	,	,	PUNCT
admet-442	248	49	r.o	r.o	PROPN
admet-442	248	50	.	.	PROPN
admet-442	248	51	pieper	pieper	PROPN
admet-442	248	52	.	.	PUNCT
admet-442	249	1	loss	loss	NOUN
admet-442	249	2	of	of	ADP
admet-442	249	3	tumor	tumor	NOUN
admet-442	249	4	suppressor	suppressor	NOUN
admet-442	249	5	pten	pten	NOUN
admet-442	249	6	function	function	NOUN
admet-442	249	7	increases	increase	VERB
admet-442	249	8	b7	b7	PROPN
admet-442	249	9	-	-	PUNCT
admet-442	249	10	h1	h1	NOUN
admet-442	249	11	expression	expression	NOUN
admet-442	249	12	and	and	CCONJ
admet-442	249	13	immunoresistance	immunoresistance	NOUN
admet-442	249	14	in	in	ADP
admet-442	249	15	glioma	glioma	NOUN
admet-442	249	16	,	,	PUNCT
admet-442	249	17	nat	nat	PROPN
admet-442	249	18	med	me	VERB
admet-442	249	19	13	13	NUM
admet-442	249	20	(	(	PUNCT
admet-442	249	21	2007	2007	NUM
admet-442	249	22	)	)	PUNCT
admet-442	249	23	84	84	NUM
admet-442	249	24	-	-	SYM
admet-442	249	25	88	88	NUM
admet-442	249	26	.	.	PUNCT
admet-442	250	1	[	[	X
admet-442	250	2	23	23	NUM
admet-442	250	3	]	]	X
admet-442	250	4	s.e	s.e	PROPN
admet-442	250	5	.	.	PROPN
admet-442	250	6	strome	strome	PROPN
admet-442	250	7	,	,	PUNCT
admet-442	250	8	h.	h.	PROPN
admet-442	250	9	dong	dong	PROPN
admet-442	250	10	,	,	PUNCT
admet-442	250	11	h.	h.	PROPN
admet-442	250	12	tamura	tamura	PROPN
admet-442	250	13	,	,	PUNCT
admet-442	250	14	s.g	s.g	PROPN
admet-442	250	15	.	.	PROPN
admet-442	250	16	voss	voss	PROPN
admet-442	250	17	,	,	PUNCT
admet-442	250	18	d.b	d.b	PROPN
admet-442	250	19	.	.	PROPN
admet-442	250	20	flies	fly	NOUN
admet-442	250	21	,	,	PUNCT
admet-442	250	22	k.	k.	PROPN
admet-442	250	23	tamada	tamada	PROPN
admet-442	250	24	,	,	PUNCT
admet-442	250	25	d.	d.	PROPN
admet-442	250	26	salomao	salomao	PROPN
admet-442	250	27	,	,	PUNCT
admet-442	250	28	j.	j.	PROPN
admet-442	250	29	cheville	cheville	PROPN
admet-442	250	30	,	,	PUNCT
admet-442	250	31	f.	f.	PROPN
admet-442	250	32	hirano	hirano	PROPN
admet-442	250	33	,	,	PUNCT
admet-442	250	34	w.	w.	PROPN
admet-442	250	35	lin	lin	PROPN
admet-442	250	36	,	,	PUNCT
admet-442	250	37	j.l	j.l	PROPN
admet-442	250	38	.	.	PROPN
admet-442	250	39	kasperbauer	kasperbauer	PROPN
admet-442	250	40	,	,	PUNCT
admet-442	250	41	k.v	k.v	PROPN
admet-442	250	42	.	.	PROPN
admet-442	250	43	ballman	ballman	PROPN
admet-442	250	44	,	,	PUNCT
admet-442	250	45	l.	l.	PROPN
admet-442	250	46	chen	chen	PROPN
admet-442	250	47	.	.	PUNCT
admet-442	251	1	b7	b7	PROPN
admet-442	251	2	-	-	PUNCT
admet-442	251	3	h1	h1	PROPN
admet-442	251	4	blockade	blockade	NOUN
admet-442	251	5	augments	augment	VERB
admet-442	251	6	adoptive	adoptive	ADJ
admet-442	251	7	t	t	NOUN
admet-442	251	8	-	-	PUNCT
admet-442	251	9	cell	cell	NOUN
admet-442	251	10	immunotherapy	immunotherapy	NOUN
admet-442	251	11	for	for	ADP
admet-442	251	12	squamous	squamous	ADJ
admet-442	251	13	cell	cell	NOUN
admet-442	251	14	carcinoma	carcinoma	NOUN
admet-442	251	15	,	,	PUNCT
admet-442	251	16	cancer	cancer	NOUN
admet-442	251	17	res	re	NOUN
admet-442	251	18	63	63	NUM
admet-442	251	19	(	(	PUNCT
admet-442	251	20	2003	2003	NUM
admet-442	251	21	)	)	PUNCT
admet-442	251	22	6501	6501	NUM
admet-442	251	23	-	-	SYM
admet-442	251	24	6505	6505	NUM
admet-442	251	25	.	.	PUNCT
admet-442	252	1	[	[	X
admet-442	252	2	24	24	NUM
admet-442	252	3	]	]	X
admet-442	252	4	j.c	j.c	PROPN
admet-442	252	5	.	.	PROPN
admet-442	252	6	routh	routh	PROPN
admet-442	252	7	,	,	PUNCT
admet-442	252	8	r.a	r.a	PROPN
admet-442	252	9	.	.	PROPN
admet-442	252	10	ashley	ashley	PROPN
admet-442	252	11	,	,	PUNCT
admet-442	252	12	t.j	t.j	PROPN
admet-442	252	13	.	.	PROPN
admet-442	252	14	sebo	sebo	PROPN
admet-442	252	15	,	,	PUNCT
admet-442	252	16	c.m	c.m	PROPN
admet-442	252	17	.	.	PROPN
admet-442	252	18	lohse	lohse	PROPN
admet-442	252	19	,	,	PUNCT
admet-442	252	20	d.a	d.a	PROPN
admet-442	252	21	.	.	PROPN
admet-442	252	22	husmann	husmann	PROPN
admet-442	252	23	,	,	PUNCT
admet-442	252	24	s.a	s.a	PROPN
admet-442	252	25	.	.	PROPN
admet-442	252	26	kramer	kramer	PROPN
admet-442	252	27	,	,	PUNCT
admet-442	252	28	e.d	e.d	PROPN
admet-442	252	29	.	.	PROPN
admet-442	252	30	kwon	kwon	PROPN
admet-442	252	31	.	.	PUNCT
admet-442	253	1	b7	b7	PROPN
admet-442	253	2	-	-	PUNCT
admet-442	253	3	h1	h1	PROPN
admet-442	253	4	expression	expression	NOUN
admet-442	253	5	in	in	ADP
admet-442	253	6	wilms	wilm	NOUN
admet-442	253	7	tumor	tumor	NOUN
admet-442	253	8	:	:	PUNCT
admet-442	253	9	correlation	correlation	NOUN
admet-442	253	10	with	with	ADP
admet-442	253	11	tumor	tumor	NOUN
admet-442	253	12	biology	biology	NOUN
admet-442	253	13	and	and	CCONJ
admet-442	253	14	disease	disease	NOUN
admet-442	253	15	recurrence	recurrence	NOUN
admet-442	253	16	,	,	PUNCT
admet-442	253	17	j	j	PROPN
admet-442	253	18	urology	urology	NOUN
admet-442	253	19	179	179	NUM
admet-442	253	20	(	(	PUNCT
admet-442	253	21	2008	2008	NUM
admet-442	253	22	)	)	PUNCT
admet-442	253	23	1954	1954	NUM
admet-442	253	24	-	-	SYM
admet-442	253	25	1959	1959	NUM
admet-442	253	26	.	.	PUNCT
admet-442	254	1	[	[	X
admet-442	254	2	25	25	NUM
admet-442	254	3	]	]	PUNCT
admet-442	254	4	r.	r.	PROPN
admet-442	254	5	hino	hino	PROPN
admet-442	254	6	,	,	PUNCT
admet-442	254	7	k.	k.	PROPN
admet-442	254	8	kabashima	kabashima	PROPN
admet-442	254	9	,	,	PUNCT
admet-442	254	10	y.	y.	PROPN
admet-442	254	11	kato	kato	PROPN
admet-442	254	12	,	,	PUNCT
admet-442	254	13	h.	h.	PROPN
admet-442	254	14	yagi	yagi	PROPN
admet-442	254	15	,	,	PUNCT
admet-442	254	16	m.	m.	NOUN
admet-442	254	17	nakamura	nakamura	PROPN
admet-442	254	18	,	,	PUNCT
admet-442	254	19	t.	t.	PROPN
admet-442	254	20	honjo	honjo	PROPN
admet-442	254	21	,	,	PUNCT
admet-442	254	22	t.	t.	PROPN
admet-442	254	23	okazaki	okazaki	PROPN
admet-442	254	24	,	,	PUNCT
admet-442	254	25	y.	y.	PROPN
admet-442	254	26	tokura	tokura	PROPN
admet-442	254	27	.	.	PUNCT
admet-442	255	1	tumor	tumor	NOUN
admet-442	255	2	cell	cell	NOUN
admet-442	255	3	expression	expression	NOUN
admet-442	255	4	of	of	ADP
admet-442	255	5	programmed	program	VERB
admet-442	255	6	cell	cell	NOUN
admet-442	255	7	death-1	death-1	PROPN
admet-442	255	8	ligand	ligand	NOUN
admet-442	255	9	1	1	NUM
admet-442	255	10	is	be	AUX
admet-442	255	11	a	a	DET
admet-442	255	12	prognostic	prognostic	ADJ
admet-442	255	13	factor	factor	NOUN
admet-442	255	14	for	for	ADP
admet-442	255	15	malignant	malignant	ADJ
admet-442	255	16	melanoma	melanoma	NOUN
admet-442	255	17	,	,	PUNCT
admet-442	255	18	cancer	cancer	NOUN
admet-442	255	19	-	-	PUNCT
admet-442	255	20	am	am	NOUN
admet-442	255	21	cancer	cancer	NOUN
admet-442	255	22	soc	soc	NOUN
admet-442	255	23	116	116	NUM
admet-442	255	24	(	(	PUNCT
admet-442	255	25	2010	2010	NUM
admet-442	255	26	)	)	PUNCT
admet-442	255	27	1757	1757	NUM
admet-442	255	28	-	-	SYM
admet-442	255	29	1766	1766	NUM
admet-442	255	30	.	.	PUNCT
admet-442	256	1	[	[	X
admet-442	256	2	26	26	NUM
admet-442	256	3	]	]	X
admet-442	256	4	j.	j.	PROPN
admet-442	256	5	hamanishi	hamanishi	PROPN
admet-442	256	6	,	,	PUNCT
admet-442	256	7	m.	m.	PROPN
admet-442	256	8	mandai	mandai	PROPN
admet-442	256	9	,	,	PUNCT
admet-442	256	10	m.	m.	NOUN
admet-442	256	11	iwasaki	iwasaki	PROPN
admet-442	256	12	,	,	PUNCT
admet-442	256	13	t.	t.	PROPN
admet-442	256	14	okazaki	okazaki	PROPN
admet-442	256	15	,	,	PUNCT
admet-442	256	16	y.	y.	PROPN
admet-442	256	17	tanaka	tanaka	PROPN
admet-442	256	18	,	,	PUNCT
admet-442	256	19	k.	k.	PROPN
admet-442	256	20	yamaguchi	yamaguchi	PROPN
admet-442	256	21	,	,	PUNCT
admet-442	256	22	t.	t.	PROPN
admet-442	256	23	higuchi	higuchi	PROPN
admet-442	256	24	,	,	PUNCT
admet-442	256	25	h.	h.	PROPN
admet-442	256	26	yagi	yagi	PROPN
admet-442	256	27	,	,	PUNCT
admet-442	256	28	k.	k.	PROPN
admet-442	256	29	takakura	takakura	PROPN
admet-442	256	30	,	,	PUNCT
admet-442	256	31	n.	n.	PROPN
admet-442	256	32	minato	minato	PROPN
admet-442	256	33	,	,	PUNCT
admet-442	256	34	t.	t.	PROPN
admet-442	256	35	honjo	honjo	PROPN
admet-442	256	36	,	,	PUNCT
admet-442	256	37	s.	s.	PROPN
admet-442	256	38	fujii	fujii	PROPN
admet-442	256	39	.	.	PUNCT
admet-442	257	1	programmed	program	VERB
admet-442	257	2	cell	cell	NOUN
admet-442	257	3	death	death	NOUN
admet-442	257	4	1	1	NUM
admet-442	257	5	ligand	ligand	NOUN
admet-442	257	6	1	1	NUM
admet-442	257	7	and	and	CCONJ
admet-442	257	8	tumor	tumor	NOUN
admet-442	257	9	-	-	PUNCT
admet-442	257	10	infiltrating	infiltrate	VERB
admet-442	257	11	cd8	cd8	PROPN
admet-442	257	12	+	+	PROPN
admet-442	257	13	t	t	PROPN
admet-442	257	14	lymphocytes	lymphocyte	NOUN
admet-442	257	15	are	be	AUX
admet-442	257	16	prognostic	prognostic	ADJ
admet-442	257	17	factors	factor	NOUN
admet-442	257	18	of	of	ADP
admet-442	257	19	human	human	ADJ
admet-442	257	20	ovarian	ovarian	ADJ
admet-442	257	21	cancer	cancer	NOUN
admet-442	257	22	,	,	PUNCT
admet-442	257	23	proc	proc	PROPN
admet-442	257	24	natl	natl	PROPN
admet-442	257	25	acad	acad	PROPN
admet-442	257	26	sci	sci	PROPN
admet-442	257	27	u	u	PROPN
admet-442	257	28	s	s	PROPN
admet-442	257	29	a	a	DET
admet-442	257	30	104	104	NUM
admet-442	257	31	(	(	PUNCT
admet-442	257	32	2007	2007	NUM
admet-442	257	33	)	)	PUNCT
admet-442	257	34	3360	3360	NUM
admet-442	257	35	-	-	SYM
admet-442	257	36	3365	3365	NUM
admet-442	257	37	.	.	PUNCT
admet-442	258	1	[	[	X
admet-442	258	2	27	27	NUM
admet-442	258	3	]	]	PUNCT
admet-442	258	4	j.	j.	PROPN
admet-442	258	5	konishi	konishi	PROPN
admet-442	258	6	,	,	PUNCT
admet-442	258	7	k.	k.	PROPN
admet-442	258	8	yamazaki	yamazaki	PROPN
admet-442	258	9	,	,	PUNCT
admet-442	258	10	m.	m.	NOUN
admet-442	258	11	azuma	azuma	PROPN
admet-442	258	12	,	,	PUNCT
admet-442	258	13	i.	i.	PROPN
admet-442	258	14	kinoshita	kinoshita	PROPN
admet-442	258	15	,	,	PUNCT
admet-442	258	16	h.	h.	PROPN
admet-442	258	17	dosaka	dosaka	PROPN
admet-442	258	18	-	-	PUNCT
admet-442	258	19	akita	akita	NOUN
admet-442	258	20	,	,	PUNCT
admet-442	258	21	m.	m.	NOUN
admet-442	258	22	nishimura	nishimura	PROPN
admet-442	258	23	.	.	PUNCT
admet-442	259	1	b7	b7	PROPN
admet-442	259	2	-	-	PUNCT
admet-442	259	3	h1	h1	PROPN
admet-442	259	4	expression	expression	NOUN
admet-442	259	5	on	on	ADP
admet-442	259	6	non	non	ADJ
admet-442	259	7	-	-	ADJ
admet-442	259	8	small	small	ADJ
admet-442	259	9	cell	cell	NOUN
admet-442	259	10	lung	lung	NOUN
admet-442	259	11	cancer	cancer	NOUN
admet-442	259	12	cells	cell	NOUN
admet-442	259	13	and	and	CCONJ
admet-442	259	14	its	its	PRON
admet-442	259	15	relationship	relationship	NOUN
admet-442	259	16	with	with	ADP
admet-442	259	17	tumor	tumor	NOUN
admet-442	259	18	-	-	PUNCT
admet-442	259	19	infiltrating	infiltrate	VERB
admet-442	259	20	lymphocytes	lymphocyte	NOUN
admet-442	259	21	and	and	CCONJ
admet-442	259	22	their	their	PRON
admet-442	259	23	pd-1	pd-1	ADJ
admet-442	259	24	expression	expression	NOUN
admet-442	259	25	,	,	PUNCT
admet-442	259	26	clin	clin	PROPN
admet-442	259	27	cancer	cancer	NOUN
admet-442	259	28	res	re	VERB
admet-442	259	29	10	10	NUM
admet-442	259	30	(	(	PUNCT
admet-442	259	31	2004	2004	NUM
admet-442	259	32	)	)	PUNCT
admet-442	259	33	5094	5094	NUM
admet-442	259	34	-	-	SYM
admet-442	259	35	5100	5100	NUM
admet-442	259	36	.	.	PUNCT
admet-442	260	1	[	[	X
admet-442	260	2	28	28	NUM
admet-442	260	3	]	]	X
admet-442	260	4	j.	j.	PROPN
admet-442	260	5	nakanishi	nakanishi	PROPN
admet-442	260	6	,	,	PUNCT
admet-442	260	7	y.	y.	PROPN
admet-442	260	8	wada	wada	PROPN
admet-442	260	9	,	,	PUNCT
admet-442	260	10	k.	k.	PROPN
admet-442	260	11	matsumoto	matsumoto	PROPN
admet-442	260	12	,	,	PUNCT
admet-442	260	13	m.	m.	NOUN
admet-442	260	14	azuma	azuma	PROPN
admet-442	260	15	,	,	PUNCT
admet-442	260	16	k.	k.	PROPN
admet-442	260	17	kikuchi	kikuchi	PROPN
admet-442	260	18	,	,	PUNCT
admet-442	260	19	s.	s.	PROPN
admet-442	260	20	ueda	ueda	PROPN
admet-442	260	21	.	.	PUNCT
admet-442	261	1	overexpression	overexpression	NOUN
admet-442	261	2	of	of	ADP
admet-442	261	3	b7	b7	PROPN
admet-442	261	4	-	-	PUNCT
admet-442	261	5	h1	h1	PROPN
admet-442	261	6	(	(	PUNCT
admet-442	261	7	pdl1	pdl1	PROPN
admet-442	261	8	)	)	PUNCT
admet-442	261	9	significantly	significantly	ADV
admet-442	261	10	associates	associate	VERB
admet-442	261	11	with	with	ADP
admet-442	261	12	tumor	tumor	NOUN
admet-442	261	13	grade	grade	NOUN
admet-442	261	14	and	and	CCONJ
admet-442	261	15	postoperative	postoperative	ADJ
admet-442	261	16	prognosis	prognosis	NOUN
admet-442	261	17	in	in	ADP
admet-442	261	18	human	human	ADJ
admet-442	261	19	urothelial	urothelial	ADJ
admet-442	261	20	cancers	cancer	NOUN
admet-442	261	21	,	,	PUNCT
admet-442	261	22	cancer	cancer	NOUN
admet-442	261	23	immunol	immunol	NOUN
admet-442	261	24	immun	immun	PROPN
admet-442	261	25	56	56	NUM
admet-442	261	26	(	(	PUNCT
admet-442	261	27	2007	2007	NUM
admet-442	261	28	)	)	PUNCT
admet-442	261	29	1173	1173	NUM
admet-442	261	30	-	-	SYM
admet-442	261	31	1182	1182	NUM
admet-442	261	32	.	.	PUNCT
admet-442	262	1	guo	guo	PROPN
admet-442	262	2	,	,	PUNCT
admet-442	262	3	lin	lin	PROPN
admet-442	262	4	and	and	CCONJ
admet-442	262	5	kwok	kwok	PROPN
admet-442	262	6	admet	admet	PROPN
admet-442	262	7	&	&	CCONJ
admet-442	262	8	dmpk	dmpk	PROPN
admet-442	262	9	5(3	5(3	NUM
admet-442	262	10	)	)	PUNCT
admet-442	262	11	(	(	PUNCT
admet-442	262	12	2017	2017	NUM
admet-442	262	13	)	)	PUNCT
admet-442	262	14	159	159	NUM
admet-442	262	15	-	-	SYM
admet-442	262	16	172	172	NUM
admet-442	262	17	168	168	NUM
admet-442	262	18	[	[	X
admet-442	262	19	29	29	NUM
admet-442	262	20	]	]	X
admet-442	262	21	y.	y.	PROPN
admet-442	262	22	ohigashi	ohigashi	PROPN
admet-442	262	23	,	,	PUNCT
admet-442	262	24	m.	m.	NOUN
admet-442	262	25	sho	sho	PROPN
admet-442	262	26	,	,	PUNCT
admet-442	262	27	y.	y.	PROPN
admet-442	262	28	yamada	yamada	PROPN
admet-442	262	29	,	,	PUNCT
admet-442	262	30	y.	y.	PROPN
admet-442	262	31	tsurui	tsurui	PROPN
admet-442	262	32	,	,	PUNCT
admet-442	262	33	k.	k.	PROPN
admet-442	262	34	hamada	hamada	PROPN
admet-442	262	35	,	,	PUNCT
admet-442	262	36	n.	n.	PROPN
admet-442	262	37	ikeda	ikeda	PROPN
admet-442	262	38	,	,	PUNCT
admet-442	262	39	t.	t.	PROPN
admet-442	262	40	mizuno	mizuno	PROPN
admet-442	262	41	,	,	PUNCT
admet-442	262	42	r.	r.	PROPN
admet-442	262	43	yoriki	yoriki	PROPN
admet-442	262	44	,	,	PUNCT
admet-442	262	45	h.	h.	PROPN
admet-442	262	46	kashizuka	kashizuka	PROPN
admet-442	262	47	,	,	PUNCT
admet-442	262	48	k.	k.	PROPN
admet-442	262	49	yane	yane	PROPN
admet-442	262	50	,	,	PUNCT
admet-442	262	51	f.	f.	PROPN
admet-442	262	52	tsushima	tsushima	PROPN
admet-442	262	53	,	,	PUNCT
admet-442	262	54	n.	n.	PROPN
admet-442	262	55	otsuki	otsuki	PROPN
admet-442	262	56	,	,	PUNCT
admet-442	262	57	h.	h.	PROPN
admet-442	262	58	yagita	yagita	PROPN
admet-442	262	59	,	,	PUNCT
admet-442	262	60	m.	m.	NOUN
admet-442	262	61	azuma	azuma	PROPN
admet-442	262	62	,	,	PUNCT
admet-442	262	63	y.	y.	PROPN
admet-442	262	64	nakajima	nakajima	PROPN
admet-442	262	65	.	.	PUNCT
admet-442	263	1	clinical	clinical	ADJ
admet-442	263	2	significance	significance	NOUN
admet-442	263	3	of	of	ADP
admet-442	263	4	programmed	program	VERB
admet-442	263	5	death-1	death-1	NUM
admet-442	263	6	ligand-1	ligand-1	NUM
admet-442	263	7	and	and	CCONJ
admet-442	263	8	programmed	program	VERB
admet-442	263	9	death-1	death-1	NUM
admet-442	263	10	ligand-2	ligand-2	NUM
admet-442	263	11	expression	expression	NOUN
admet-442	263	12	in	in	ADP
admet-442	263	13	human	human	ADJ
admet-442	263	14	esophageal	esophageal	ADJ
admet-442	263	15	cancer	cancer	NOUN
admet-442	263	16	,	,	PUNCT
admet-442	263	17	clin	clin	PROPN
admet-442	263	18	cancer	cancer	NOUN
admet-442	263	19	res	re	VERB
admet-442	263	20	11	11	NUM
admet-442	263	21	(	(	PUNCT
admet-442	263	22	2005	2005	NUM
admet-442	263	23	)	)	PUNCT
admet-442	263	24	2947	2947	NUM
admet-442	263	25	-	-	SYM
admet-442	263	26	2953	2953	NUM
admet-442	263	27	.	.	PUNCT
admet-442	264	1	[	[	X
admet-442	264	2	30	30	NUM
admet-442	264	3	]	]	X
admet-442	264	4	r.	r.	PROPN
admet-442	264	5	karim	karim	PROPN
admet-442	264	6	,	,	PUNCT
admet-442	264	7	e.s	e.s	PROPN
admet-442	264	8	.	.	PROPN
admet-442	264	9	jordanova	jordanova	PROPN
admet-442	264	10	,	,	PUNCT
admet-442	264	11	s.j	s.j	PROPN
admet-442	264	12	.	.	PROPN
admet-442	264	13	piersma	piersma	PROPN
admet-442	264	14	,	,	PUNCT
admet-442	264	15	g.g	g.g	PROPN
admet-442	264	16	.	.	PROPN
admet-442	264	17	kenter	kenter	PROPN
admet-442	264	18	,	,	PUNCT
admet-442	264	19	l.	l.	PROPN
admet-442	264	20	chen	chen	PROPN
admet-442	264	21	,	,	PUNCT
admet-442	264	22	j.m	j.m	PROPN
admet-442	264	23	.	.	PROPN
admet-442	264	24	boer	boer	PROPN
admet-442	264	25	,	,	PUNCT
admet-442	264	26	c.j	c.j	PROPN
admet-442	264	27	.	.	PROPN
admet-442	264	28	melief	melief	PROPN
admet-442	264	29	,	,	PUNCT
admet-442	264	30	s.h	s.h	PROPN
admet-442	264	31	.	.	PROPN
admet-442	264	32	van	van	PROPN
admet-442	264	33	der	der	PROPN
admet-442	264	34	burg	burg	PROPN
admet-442	264	35	.	.	PUNCT
admet-442	265	1	tumor	tumor	NOUN
admet-442	265	2	-	-	PUNCT
admet-442	265	3	expressed	express	VERB
admet-442	265	4	b7	b7	PROPN
admet-442	265	5	-	-	PUNCT
admet-442	265	6	h1	h1	PROPN
admet-442	265	7	and	and	CCONJ
admet-442	265	8	b7	b7	PROPN
admet-442	265	9	-	-	PUNCT
admet-442	265	10	dc	dc	PROPN
admet-442	265	11	in	in	ADP
admet-442	265	12	relation	relation	NOUN
admet-442	265	13	to	to	ADP
admet-442	265	14	pd-1	pd-1	NOUN
admet-442	265	15	+	+	PROPN
admet-442	265	16	t	t	NOUN
admet-442	265	17	-	-	PUNCT
admet-442	265	18	cell	cell	NOUN
admet-442	265	19	infiltration	infiltration	NOUN
admet-442	265	20	and	and	CCONJ
admet-442	265	21	survival	survival	NOUN
admet-442	265	22	of	of	ADP
admet-442	265	23	patients	patient	NOUN
admet-442	265	24	with	with	ADP
admet-442	265	25	cervical	cervical	ADJ
admet-442	265	26	carcinoma	carcinoma	NOUN
admet-442	265	27	,	,	PUNCT
admet-442	265	28	clin	clin	PROPN
admet-442	265	29	cancer	cancer	NOUN
admet-442	265	30	res	re	VERB
admet-442	265	31	15	15	NUM
admet-442	265	32	(	(	PUNCT
admet-442	265	33	2009	2009	NUM
admet-442	265	34	)	)	PUNCT
admet-442	265	35	6341	6341	NUM
admet-442	265	36	-	-	SYM
admet-442	265	37	6347	6347	NUM
admet-442	265	38	.	.	PUNCT
admet-442	266	1	[	[	X
admet-442	266	2	31	31	NUM
admet-442	266	3	]	]	PUNCT
admet-442	266	4	t.	t.	NOUN
admet-442	266	5	nomi	nomi	PROPN
admet-442	266	6	,	,	PUNCT
admet-442	266	7	m.	m.	NOUN
admet-442	266	8	sho	sho	NOUN
admet-442	266	9	,	,	PUNCT
admet-442	266	10	t.	t.	PROPN
admet-442	266	11	akahori	akahori	PROPN
admet-442	266	12	,	,	PUNCT
admet-442	266	13	k.	k.	PROPN
admet-442	266	14	hamada	hamada	PROPN
admet-442	266	15	,	,	PUNCT
admet-442	266	16	a.	a.	PROPN
admet-442	266	17	kubo	kubo	PROPN
admet-442	266	18	,	,	PUNCT
admet-442	266	19	h.	h.	PROPN
admet-442	266	20	kanehiro	kanehiro	PROPN
admet-442	266	21	,	,	PUNCT
admet-442	266	22	s.	s.	PROPN
admet-442	266	23	nakamura	nakamura	PROPN
admet-442	266	24	,	,	PUNCT
admet-442	266	25	k.	k.	PROPN
admet-442	266	26	enomoto	enomoto	PROPN
admet-442	266	27	,	,	PUNCT
admet-442	266	28	h.	h.	PROPN
admet-442	266	29	yagita	yagita	PROPN
admet-442	266	30	,	,	PUNCT
admet-442	266	31	m.	m.	NOUN
admet-442	266	32	azuma	azuma	PROPN
admet-442	266	33	,	,	PUNCT
admet-442	266	34	y.	y.	PROPN
admet-442	266	35	nakajima	nakajima	PROPN
admet-442	266	36	.	.	PUNCT
admet-442	267	1	clinical	clinical	ADJ
admet-442	267	2	significance	significance	NOUN
admet-442	267	3	and	and	CCONJ
admet-442	267	4	therapeutic	therapeutic	ADJ
admet-442	267	5	potential	potential	NOUN
admet-442	267	6	of	of	ADP
admet-442	267	7	the	the	DET
admet-442	267	8	programmed	program	VERB
admet-442	267	9	death-1	death-1	NUM
admet-442	267	10	ligand	ligand	ADV
admet-442	267	11	/	/	SYM
admet-442	267	12	programmed	program	VERB
admet-442	267	13	death-1	death-1	NUM
admet-442	267	14	pathway	pathway	NOUN
admet-442	267	15	in	in	ADP
admet-442	267	16	human	human	ADJ
admet-442	267	17	pancreatic	pancreatic	ADJ
admet-442	267	18	cancer	cancer	NOUN
admet-442	267	19	,	,	PUNCT
admet-442	267	20	clin	clin	PROPN
admet-442	267	21	cancer	cancer	NOUN
admet-442	267	22	res	re	VERB
admet-442	267	23	13	13	NUM
admet-442	267	24	(	(	PUNCT
admet-442	267	25	2007	2007	NUM
admet-442	267	26	)	)	PUNCT
admet-442	267	27	21512157	21512157	NUM
admet-442	267	28	.	.	PUNCT
admet-442	268	1	[	[	X
admet-442	268	2	32	32	NUM
admet-442	268	3	]	]	PUNCT
admet-442	268	4	z.	z.	PROPN
admet-442	268	5	zeng	zeng	PROPN
admet-442	268	6	,	,	PUNCT
admet-442	268	7	f.	f.	PROPN
admet-442	268	8	shi	shi	PROPN
admet-442	268	9	,	,	PUNCT
admet-442	268	10	l.	l.	PROPN
admet-442	268	11	zhou	zhou	PROPN
admet-442	268	12	,	,	PUNCT
admet-442	268	13	m.n	m.n	PROPN
admet-442	268	14	.	.	PROPN
admet-442	268	15	zhang	zhang	PROPN
admet-442	268	16	,	,	PUNCT
admet-442	268	17	y.	y.	PROPN
admet-442	268	18	chen	chen	PROPN
admet-442	268	19	,	,	PUNCT
admet-442	268	20	x.j	x.j	PROPN
admet-442	268	21	.	.	PROPN
admet-442	268	22	chang	chang	PROPN
admet-442	268	23	,	,	PUNCT
admet-442	268	24	y.y	y.y	PROPN
admet-442	268	25	.	.	PROPN
admet-442	268	26	lu	lu	PROPN
admet-442	268	27	,	,	PUNCT
admet-442	268	28	w.l	w.l	PROPN
admet-442	268	29	.	.	PROPN
admet-442	268	30	bai	bai	PROPN
admet-442	268	31	,	,	PUNCT
admet-442	268	32	j.h	j.h	PROPN
admet-442	268	33	.	.	PROPN
admet-442	268	34	qu	qu	PROPN
admet-442	268	35	,	,	PUNCT
admet-442	268	36	c.p	c.p	PROPN
admet-442	268	37	.	.	PROPN
admet-442	268	38	wang	wang	PROPN
admet-442	268	39	,	,	PUNCT
admet-442	268	40	h.	h.	PROPN
admet-442	268	41	wang	wang	PROPN
admet-442	268	42	,	,	PUNCT
admet-442	268	43	m.	m.	PROPN
admet-442	268	44	lou	lou	PROPN
admet-442	268	45	,	,	PUNCT
admet-442	268	46	f.s	f.s	PROPN
admet-442	268	47	.	.	PROPN
admet-442	268	48	wang	wang	PROPN
admet-442	268	49	,	,	PUNCT
admet-442	268	50	j.y	j.y	PROPN
admet-442	268	51	.	.	PROPN
admet-442	268	52	lv	lv	PROPN
admet-442	268	53	,	,	PUNCT
admet-442	268	54	y.p	y.p	PROPN
admet-442	268	55	.	.	PROPN
admet-442	268	56	yang	yang	PROPN
admet-442	268	57	.	.	PUNCT
admet-442	269	1	upregulation	upregulation	NOUN
admet-442	269	2	of	of	ADP
admet-442	269	3	circulating	circulate	VERB
admet-442	269	4	pd	pd	PROPN
admet-442	269	5	-	-	PUNCT
admet-442	269	6	l1	l1	PROPN
admet-442	269	7	/	/	SYM
admet-442	269	8	pd-1	pd-1	VERB
admet-442	269	9	is	be	AUX
admet-442	269	10	associated	associate	VERB
admet-442	269	11	with	with	ADP
admet-442	269	12	poor	poor	ADJ
admet-442	269	13	post	post	ADJ
admet-442	269	14	-	-	ADJ
admet-442	269	15	cryoablation	cryoablation	ADJ
admet-442	269	16	prognosis	prognosis	NOUN
admet-442	269	17	in	in	ADP
admet-442	269	18	patients	patient	NOUN
admet-442	269	19	with	with	ADP
admet-442	269	20	hbv	hbv	NOUN
admet-442	269	21	-	-	PUNCT
admet-442	269	22	related	relate	VERB
admet-442	269	23	hepatocellular	hepatocellular	ADJ
admet-442	269	24	carcinoma	carcinoma	NOUN
admet-442	269	25	,	,	PUNCT
admet-442	269	26	plos	plos	PROPN
admet-442	269	27	one	one	NUM
admet-442	269	28	6	6	NUM
admet-442	269	29	(	(	PUNCT
admet-442	269	30	2011	2011	NUM
admet-442	269	31	)	)	PUNCT
admet-442	269	32	.	.	PUNCT
admet-442	270	1	[	[	X
admet-442	270	2	33	33	NUM
admet-442	270	3	]	]	PUNCT
admet-442	270	4	s.	s.	PROPN
admet-442	270	5	muenst	muenst	PROPN
admet-442	270	6	,	,	PUNCT
admet-442	270	7	a.r	a.r	PROPN
admet-442	270	8	.	.	PROPN
admet-442	270	9	schaerli	schaerli	PROPN
admet-442	270	10	,	,	PUNCT
admet-442	270	11	f.	f.	PROPN
admet-442	270	12	gao	gao	PROPN
admet-442	270	13	,	,	PUNCT
admet-442	270	14	s.	s.	PROPN
admet-442	270	15	daster	daster	PROPN
admet-442	270	16	,	,	PUNCT
admet-442	270	17	e.	e.	PROPN
admet-442	270	18	trella	trella	PROPN
admet-442	270	19	,	,	PUNCT
admet-442	270	20	r.a	r.a	PROPN
admet-442	270	21	.	.	PROPN
admet-442	270	22	droeser	droeser	PROPN
admet-442	270	23	,	,	PUNCT
admet-442	270	24	m.g	m.g	PROPN
admet-442	270	25	.	.	PROPN
admet-442	270	26	muraro	muraro	PROPN
admet-442	270	27	,	,	PUNCT
admet-442	270	28	p.	p.	PROPN
admet-442	270	29	zajac	zajac	PROPN
admet-442	270	30	,	,	PUNCT
admet-442	270	31	r.	r.	PROPN
admet-442	270	32	zanetti	zanetti	PROPN
admet-442	270	33	,	,	PUNCT
admet-442	270	34	w.e	w.e	PROPN
admet-442	270	35	.	.	PROPN
admet-442	270	36	gillanders	gillander	NOUN
admet-442	270	37	,	,	PUNCT
admet-442	270	38	w.p	w.p	PROPN
admet-442	270	39	.	.	PROPN
admet-442	270	40	weber	weber	PROPN
admet-442	270	41	,	,	PUNCT
admet-442	270	42	s.d	s.d	PROPN
admet-442	270	43	.	.	PROPN
admet-442	270	44	soysal	soysal	PROPN
admet-442	270	45	.	.	PUNCT
admet-442	271	1	expression	expression	NOUN
admet-442	271	2	of	of	ADP
admet-442	271	3	programmed	program	VERB
admet-442	271	4	death	death	NOUN
admet-442	271	5	ligand	ligand	NOUN
admet-442	271	6	1	1	NUM
admet-442	271	7	(	(	PUNCT
admet-442	271	8	pd	pd	NOUN
admet-442	271	9	-	-	PUNCT
admet-442	271	10	l1	l1	PROPN
admet-442	271	11	)	)	PUNCT
admet-442	271	12	is	be	AUX
admet-442	271	13	associated	associate	VERB
admet-442	271	14	with	with	ADP
admet-442	271	15	poor	poor	ADJ
admet-442	271	16	prognosis	prognosis	NOUN
admet-442	271	17	in	in	ADP
admet-442	271	18	human	human	ADJ
admet-442	271	19	breast	breast	NOUN
admet-442	271	20	cancer	cancer	NOUN
admet-442	271	21	,	,	PUNCT
admet-442	271	22	breast	breast	NOUN
admet-442	271	23	cancer	cancer	NOUN
admet-442	271	24	res	re	NOUN
admet-442	271	25	tr	tr	VERB
admet-442	271	26	146	146	NUM
admet-442	271	27	(	(	PUNCT
admet-442	271	28	2014	2014	NUM
admet-442	271	29	)	)	PUNCT
admet-442	271	30	15	15	NUM
admet-442	271	31	-	-	SYM
admet-442	271	32	24	24	NUM
admet-442	271	33	.	.	PUNCT
admet-442	272	1	[	[	X
admet-442	272	2	34	34	NUM
admet-442	272	3	]	]	X
admet-442	272	4	c.t	c.t	PROPN
admet-442	272	5	.	.	PROPN
admet-442	272	6	wu	wu	PROPN
admet-442	272	7	,	,	PUNCT
admet-442	272	8	w.c	w.c	PROPN
admet-442	272	9	.	.	PROPN
admet-442	272	10	chen	chen	PROPN
admet-442	272	11	,	,	PUNCT
admet-442	272	12	y.h	y.h	PROPN
admet-442	272	13	.	.	PROPN
admet-442	272	14	chang	chang	PROPN
admet-442	272	15	,	,	PUNCT
admet-442	272	16	w.y	w.y	PROPN
admet-442	272	17	.	.	PROPN
admet-442	272	18	lin	lin	PROPN
admet-442	272	19	,	,	PUNCT
admet-442	272	20	m.f	m.f	PROPN
admet-442	272	21	.	.	PUNCT
admet-442	272	22	chen	chen	PROPN
admet-442	272	23	.	.	PUNCT
admet-442	273	1	the	the	DET
admet-442	273	2	role	role	NOUN
admet-442	273	3	of	of	ADP
admet-442	273	4	pd	pd	PROPN
admet-442	273	5	-	-	PROPN
admet-442	273	6	l1	l1	PROPN
admet-442	273	7	in	in	ADP
admet-442	273	8	the	the	DET
admet-442	273	9	radiation	radiation	NOUN
admet-442	273	10	response	response	NOUN
admet-442	273	11	and	and	CCONJ
admet-442	273	12	clinical	clinical	ADJ
admet-442	273	13	outcome	outcome	NOUN
admet-442	273	14	for	for	ADP
admet-442	273	15	bladder	bladder	NOUN
admet-442	273	16	cancer	cancer	NOUN
admet-442	273	17	,	,	PUNCT
admet-442	273	18	sci	sci	PROPN
admet-442	273	19	rep	rep	PROPN
admet-442	273	20	6	6	NUM
admet-442	273	21	(	(	PUNCT
admet-442	273	22	2016	2016	NUM
admet-442	273	23	)	)	PUNCT
admet-442	273	24	19740	19740	NUM
admet-442	273	25	.	.	PUNCT
admet-442	274	1	[	[	X
admet-442	274	2	35	35	NUM
admet-442	274	3	]	]	X
admet-442	274	4	s.	s.	PROPN
admet-442	274	5	derks	derks	PROPN
admet-442	274	6	,	,	PUNCT
admet-442	274	7	x.y	x.y	PROPN
admet-442	274	8	.	.	PROPN
admet-442	274	9	liao	liao	PROPN
admet-442	274	10	,	,	PUNCT
admet-442	274	11	a.m.	a.m.	PROPN
admet-442	274	12	chiaravalli	chiaravalli	PROPN
admet-442	274	13	,	,	PUNCT
admet-442	274	14	x.s	x.s	PROPN
admet-442	274	15	.	.	PROPN
admet-442	274	16	xu	xu	PROPN
admet-442	274	17	,	,	PUNCT
admet-442	274	18	m.c	m.c	PROPN
admet-442	274	19	.	.	PROPN
admet-442	274	20	camargo	camargo	PROPN
admet-442	274	21	,	,	PUNCT
admet-442	274	22	e.	e.	PROPN
admet-442	274	23	solcia	solcia	PROPN
admet-442	274	24	,	,	PUNCT
admet-442	274	25	f.	f.	PROPN
admet-442	274	26	sessa	sessa	PROPN
admet-442	274	27	,	,	PUNCT
admet-442	274	28	t.	t.	NOUN
admet-442	274	29	fleitas	fleita	NOUN
admet-442	274	30	,	,	PUNCT
admet-442	274	31	g.j	g.j	PROPN
admet-442	274	32	.	.	PROPN
admet-442	274	33	freeman	freeman	PROPN
admet-442	274	34	,	,	PUNCT
admet-442	274	35	s.j	s.j	PROPN
admet-442	274	36	.	.	PROPN
admet-442	274	37	rodig	rodig	PROPN
admet-442	274	38	,	,	PUNCT
admet-442	274	39	c.s	c.s	PROPN
admet-442	274	40	.	.	PROPN
admet-442	274	41	rabkin	rabkin	PROPN
admet-442	274	42	,	,	PUNCT
admet-442	274	43	a.j	a.j	PROPN
admet-442	274	44	.	.	PROPN
admet-442	274	45	bass	bass	PROPN
admet-442	274	46	.	.	PUNCT
admet-442	275	1	abundant	abundant	ADJ
admet-442	275	2	pd	pd	PROPN
admet-442	275	3	-	-	PUNCT
admet-442	275	4	l1	l1	PROPN
admet-442	275	5	expression	expression	NOUN
admet-442	275	6	in	in	ADP
admet-442	275	7	epstein	epstein	PROPN
admet-442	275	8	-	-	PUNCT
admet-442	275	9	barr	barr	PROPN
admet-442	275	10	virusinfected	virusinfecte	VERB
admet-442	275	11	gastric	gastric	ADJ
admet-442	275	12	cancers	cancer	NOUN
admet-442	275	13	,	,	PUNCT
admet-442	275	14	oncotarget	oncotarget	VERB
admet-442	275	15	7	7	NUM
admet-442	275	16	(	(	PUNCT
admet-442	275	17	2016	2016	NUM
admet-442	275	18	)	)	PUNCT
admet-442	275	19	32925	32925	NUM
admet-442	275	20	-	-	SYM
admet-442	275	21	32932	32932	NUM
admet-442	275	22	.	.	PUNCT
admet-442	276	1	[	[	X
admet-442	276	2	36	36	NUM
admet-442	276	3	]	]	PUNCT
admet-442	276	4	l.	l.	PROPN
admet-442	276	5	zhang	zhang	PROPN
admet-442	276	6	,	,	PUNCT
admet-442	276	7	t.f	t.f	PROPN
admet-442	276	8	.	.	PROPN
admet-442	276	9	gajewski	gajewski	PROPN
admet-442	276	10	,	,	PUNCT
admet-442	276	11	j.	j.	PROPN
admet-442	276	12	kline	kline	PROPN
admet-442	276	13	.	.	PUNCT
admet-442	277	1	pd-1	pd-1	ADP
admet-442	277	2	/	/	SYM
admet-442	277	3	pd	pd	ADJ
admet-442	277	4	-	-	PUNCT
admet-442	277	5	l1	l1	PROPN
admet-442	277	6	interactions	interaction	NOUN
admet-442	277	7	inhibit	inhibit	VERB
admet-442	277	8	antitumor	antitumor	PROPN
admet-442	277	9	immune	immune	ADJ
admet-442	277	10	responses	response	NOUN
admet-442	277	11	in	in	ADP
admet-442	277	12	a	a	DET
admet-442	277	13	murine	murine	ADJ
admet-442	277	14	acute	acute	ADJ
admet-442	277	15	myeloid	myeloid	NOUN
admet-442	277	16	leukemia	leukemia	NOUN
admet-442	277	17	model	model	NOUN
admet-442	277	18	,	,	PUNCT
admet-442	277	19	blood	blood	NOUN
admet-442	277	20	114	114	NUM
admet-442	277	21	(	(	PUNCT
admet-442	277	22	2009	2009	NUM
admet-442	277	23	)	)	PUNCT
admet-442	277	24	1545	1545	NUM
admet-442	277	25	-	-	SYM
admet-442	277	26	1552	1552	NUM
admet-442	277	27	.	.	PUNCT
admet-442	278	1	[	[	X
admet-442	278	2	37	37	NUM
admet-442	278	3	]	]	X
admet-442	278	4	y.	y.	PROPN
admet-442	278	5	iwai	iwai	PROPN
admet-442	278	6	,	,	PUNCT
admet-442	278	7	m.	m.	NOUN
admet-442	278	8	ishida	ishida	PROPN
admet-442	278	9	,	,	PUNCT
admet-442	278	10	y.	y.	PROPN
admet-442	278	11	tanaka	tanaka	PROPN
admet-442	278	12	,	,	PUNCT
admet-442	278	13	t.	t.	PROPN
admet-442	278	14	okazaki	okazaki	PROPN
admet-442	278	15	,	,	PUNCT
admet-442	278	16	t.	t.	PROPN
admet-442	278	17	honjo	honjo	PROPN
admet-442	278	18	,	,	PUNCT
admet-442	278	19	n.	n.	PROPN
admet-442	278	20	minato	minato	PROPN
admet-442	278	21	.	.	PUNCT
admet-442	279	1	involvement	involvement	NOUN
admet-442	279	2	of	of	ADP
admet-442	279	3	pd	pd	PROPN
admet-442	279	4	-	-	PROPN
admet-442	279	5	l1	l1	PROPN
admet-442	279	6	on	on	ADP
admet-442	279	7	tumor	tumor	NOUN
admet-442	279	8	cells	cell	NOUN
admet-442	279	9	in	in	ADP
admet-442	279	10	the	the	DET
admet-442	279	11	escape	escape	NOUN
admet-442	279	12	from	from	ADP
admet-442	279	13	host	host	NOUN
admet-442	279	14	immune	immune	ADJ
admet-442	279	15	system	system	NOUN
admet-442	279	16	and	and	CCONJ
admet-442	279	17	tumor	tumor	NOUN
admet-442	279	18	immunotherapy	immunotherapy	NOUN
admet-442	279	19	by	by	ADP
admet-442	279	20	pd	pd	PROPN
admet-442	279	21	-	-	PROPN
admet-442	279	22	l1	l1	PROPN
admet-442	279	23	blockade	blockade	NOUN
admet-442	279	24	,	,	PUNCT
admet-442	279	25	proc	proc	PROPN
admet-442	279	26	natl	natl	PROPN
admet-442	279	27	acad	acad	PROPN
admet-442	279	28	sci	sci	PROPN
admet-442	279	29	u	u	PROPN
admet-442	279	30	s	s	PROPN
admet-442	279	31	a	a	PRON
admet-442	279	32	99	99	NUM
admet-442	279	33	(	(	PUNCT
admet-442	279	34	2002	2002	NUM
admet-442	279	35	)	)	PUNCT
admet-442	279	36	12293	12293	NUM
admet-442	279	37	-	-	SYM
admet-442	279	38	12297	12297	NUM
admet-442	279	39	.	.	PUNCT
admet-442	280	1	[	[	X
admet-442	280	2	38	38	NUM
admet-442	280	3	]	]	SYM
admet-442	280	4	s.c	s.c	PROPN
admet-442	280	5	.	.	PROPN
admet-442	280	6	liang	liang	PROPN
admet-442	280	7	,	,	PUNCT
admet-442	280	8	y.e	y.e	PROPN
admet-442	280	9	.	.	PROPN
admet-442	280	10	latchman	latchman	PROPN
admet-442	280	11	,	,	PUNCT
admet-442	280	12	j.e	j.e	PROPN
admet-442	280	13	.	.	PROPN
admet-442	280	14	buhlmann	buhlmann	PROPN
admet-442	280	15	,	,	PUNCT
admet-442	280	16	m.f	m.f	PROPN
admet-442	280	17	.	.	PROPN
admet-442	280	18	tomczak	tomczak	NOUN
admet-442	280	19	,	,	PUNCT
admet-442	280	20	b.h	b.h	PROPN
admet-442	280	21	.	.	PUNCT
admet-442	280	22	horwitz	horwitz	PROPN
admet-442	280	23	,	,	PUNCT
admet-442	280	24	g.j	g.j	PROPN
admet-442	280	25	.	.	PROPN
admet-442	280	26	freeman	freeman	PROPN
admet-442	280	27	,	,	PUNCT
admet-442	280	28	a.h	a.h	PROPN
admet-442	280	29	.	.	PROPN
admet-442	280	30	sharpe	sharpe	PROPN
admet-442	280	31	.	.	PUNCT
admet-442	280	32	regulation	regulation	NOUN
admet-442	280	33	of	of	ADP
admet-442	280	34	pd-1	pd-1	ADP
admet-442	280	35	,	,	PUNCT
admet-442	280	36	pd	pd	PROPN
admet-442	280	37	-	-	PROPN
admet-442	280	38	l1	l1	PROPN
admet-442	280	39	,	,	PUNCT
admet-442	280	40	and	and	CCONJ
admet-442	280	41	pd	pd	ADJ
admet-442	280	42	-	-	PUNCT
admet-442	280	43	l2	l2	NOUN
admet-442	280	44	expression	expression	NOUN
admet-442	280	45	during	during	ADP
admet-442	280	46	normal	normal	ADJ
admet-442	280	47	and	and	CCONJ
admet-442	280	48	autoimmune	autoimmune	ADJ
admet-442	280	49	responses	response	NOUN
admet-442	280	50	,	,	PUNCT
admet-442	280	51	eur	eur	PROPN
admet-442	280	52	j	j	PROPN
admet-442	280	53	immunol	immunol	NOUN
admet-442	280	54	33	33	NUM
admet-442	280	55	(	(	PUNCT
admet-442	280	56	2003	2003	NUM
admet-442	280	57	)	)	PUNCT
admet-442	280	58	2706	2706	NUM
admet-442	280	59	-	-	SYM
admet-442	280	60	2716	2716	NUM
admet-442	280	61	.	.	PUNCT
admet-442	281	1	[	[	X
admet-442	281	2	39	39	NUM
admet-442	281	3	]	]	X
admet-442	281	4	m.j	m.j	PROPN
admet-442	281	5	.	.	PROPN
admet-442	281	6	ansari	ansari	PROPN
admet-442	281	7	,	,	PUNCT
admet-442	281	8	a.d	a.d	PROPN
admet-442	281	9	.	.	PROPN
admet-442	281	10	salama	salama	PROPN
admet-442	281	11	,	,	PUNCT
admet-442	281	12	t.	t.	PROPN
admet-442	281	13	chitnis	chitnis	PROPN
admet-442	281	14	,	,	PUNCT
admet-442	281	15	r.n	r.n	PROPN
admet-442	281	16	.	.	PROPN
admet-442	281	17	smith	smith	PROPN
admet-442	281	18	,	,	PUNCT
admet-442	281	19	h.	h.	PROPN
admet-442	281	20	yagita	yagita	PROPN
admet-442	281	21	,	,	PUNCT
admet-442	281	22	h.	h.	PROPN
admet-442	281	23	akiba	akiba	PROPN
admet-442	281	24	,	,	PUNCT
admet-442	281	25	t.	t.	PROPN
admet-442	281	26	yamazaki	yamazaki	PROPN
admet-442	281	27	,	,	PUNCT
admet-442	281	28	m.	m.	NOUN
admet-442	281	29	azuma	azuma	PROPN
admet-442	281	30	,	,	PUNCT
admet-442	281	31	h.	h.	PROPN
admet-442	281	32	iwai	iwai	PROPN
admet-442	281	33	,	,	PUNCT
admet-442	281	34	s.j	s.j	PROPN
admet-442	281	35	.	.	PROPN
admet-442	281	36	khoury	khoury	PROPN
admet-442	281	37	,	,	PUNCT
admet-442	281	38	h.	h.	PROPN
admet-442	281	39	auchincloss	auchincloss	PROPN
admet-442	281	40	,	,	PUNCT
admet-442	281	41	jr	jr	PROPN
admet-442	281	42	.	.	PROPN
admet-442	281	43	,	,	PUNCT
admet-442	281	44	m.h	m.h	PROPN
admet-442	281	45	.	.	PROPN
admet-442	281	46	sayegh	sayegh	PROPN
admet-442	281	47	.	.	PUNCT
admet-442	282	1	the	the	DET
admet-442	282	2	programmed	program	VERB
admet-442	282	3	death-1	death-1	PROPN
admet-442	282	4	(	(	PUNCT
admet-442	282	5	pd-1	pd-1	ADJ
admet-442	282	6	)	)	PUNCT
admet-442	282	7	pathway	pathway	NOUN
admet-442	282	8	regulates	regulate	VERB
admet-442	282	9	autoimmune	autoimmune	ADJ
admet-442	282	10	diabetes	diabetes	NOUN
admet-442	282	11	in	in	ADP
admet-442	282	12	nonobese	nonobese	ADJ
admet-442	282	13	diabetic	diabetic	ADJ
admet-442	282	14	(	(	PUNCT
admet-442	282	15	nod	nod	NOUN
admet-442	282	16	)	)	PUNCT
admet-442	282	17	mice	mouse	NOUN
admet-442	282	18	,	,	PUNCT
admet-442	282	19	j	j	PROPN
admet-442	282	20	exp	exp	NOUN
admet-442	282	21	med	med	PROPN
admet-442	282	22	198	198	NUM
admet-442	282	23	(	(	PUNCT
admet-442	282	24	2003	2003	NUM
admet-442	282	25	)	)	PUNCT
admet-442	282	26	63	63	NUM
admet-442	282	27	-	-	SYM
admet-442	282	28	69	69	NUM
admet-442	282	29	.	.	PUNCT
admet-442	283	1	[	[	X
admet-442	283	2	40	40	NUM
admet-442	283	3	]	]	X
admet-442	283	4	t.l	t.l	PROPN
admet-442	283	5	.	.	PROPN
admet-442	283	6	delovitch	delovitch	PROPN
admet-442	283	7	,	,	PUNCT
admet-442	283	8	b.	b.	PROPN
admet-442	283	9	singh	singh	PROPN
admet-442	283	10	.	.	PUNCT
admet-442	284	1	the	the	DET
admet-442	284	2	nonobese	nonobese	ADJ
admet-442	284	3	diabetic	diabetic	ADJ
admet-442	284	4	mouse	mouse	NOUN
admet-442	284	5	as	as	ADP
admet-442	284	6	a	a	DET
admet-442	284	7	model	model	NOUN
admet-442	284	8	of	of	ADP
admet-442	284	9	autoimmune	autoimmune	ADJ
admet-442	284	10	diabetes	diabetes	NOUN
admet-442	284	11	:	:	PUNCT
admet-442	284	12	immune	immune	ADJ
admet-442	284	13	dysregulation	dysregulation	NOUN
admet-442	284	14	gets	get	VERB
admet-442	284	15	the	the	DET
admet-442	284	16	nod	nod	NOUN
admet-442	284	17	,	,	PUNCT
admet-442	284	18	immunity	immunity	NOUN
admet-442	284	19	7	7	NUM
admet-442	284	20	(	(	PUNCT
admet-442	284	21	1997	1997	NUM
admet-442	284	22	)	)	PUNCT
admet-442	284	23	727	727	NUM
admet-442	284	24	-	-	SYM
admet-442	284	25	738	738	NUM
admet-442	284	26	.	.	PUNCT
admet-442	285	1	[	[	X
admet-442	285	2	41	41	NUM
admet-442	285	3	]	]	PUNCT
admet-442	285	4	b.	b.	PROPN
admet-442	285	5	zhu	zhu	PROPN
admet-442	285	6	,	,	PUNCT
admet-442	285	7	i.	i.	PROPN
admet-442	285	8	guleria	guleria	PROPN
admet-442	285	9	,	,	PUNCT
admet-442	285	10	a.	a.	NOUN
admet-442	285	11	khosroshahi	khosroshahi	PROPN
admet-442	285	12	,	,	PUNCT
admet-442	285	13	t.	t.	PROPN
admet-442	285	14	chitnis	chitnis	PROPN
admet-442	285	15	,	,	PUNCT
admet-442	285	16	j.	j.	PROPN
admet-442	285	17	imitola	imitola	PROPN
admet-442	285	18	,	,	PUNCT
admet-442	285	19	m.	m.	NOUN
admet-442	285	20	azuma	azuma	PROPN
admet-442	285	21	,	,	PUNCT
admet-442	285	22	h.	h.	PROPN
admet-442	285	23	yagita	yagita	PROPN
admet-442	285	24	,	,	PUNCT
admet-442	285	25	m.h	m.h	PROPN
admet-442	285	26	.	.	PROPN
admet-442	285	27	sayegh	sayegh	PROPN
admet-442	285	28	,	,	PUNCT
admet-442	285	29	s.j	s.j	PROPN
admet-442	285	30	.	.	PROPN
admet-442	285	31	khoury	khoury	PROPN
admet-442	285	32	.	.	PUNCT
admet-442	285	33	differential	differential	ADJ
admet-442	285	34	role	role	NOUN
admet-442	285	35	of	of	ADP
admet-442	285	36	programmed	program	VERB
admet-442	285	37	death	death	NOUN
admet-442	285	38	-	-	PUNCT
admet-442	285	39	ligand	ligand	NOUN
admet-442	285	40	1	1	NUM
admet-442	285	41	[	[	X
admet-442	285	42	corrected	correct	VERB
admet-442	285	43	]	]	PUNCT
admet-442	285	44	and	and	CCONJ
admet-442	285	45	programmed	program	VERB
admet-442	285	46	death	death	NOUN
admet-442	285	47	-	-	PUNCT
admet-442	285	48	ligand	ligand	NOUN
admet-442	285	49	2	2	NUM
admet-442	285	50	[	[	X
admet-442	285	51	corrected	correct	VERB
admet-442	285	52	]	]	PUNCT
admet-442	285	53	in	in	ADP
admet-442	285	54	regulating	regulate	VERB
admet-442	285	55	the	the	DET
admet-442	285	56	susceptibility	susceptibility	NOUN
admet-442	285	57	and	and	CCONJ
admet-442	285	58	chronic	chronic	ADJ
admet-442	285	59	progression	progression	NOUN
admet-442	285	60	of	of	ADP
admet-442	285	61	experimental	experimental	ADJ
admet-442	285	62	autoimmune	autoimmune	ADJ
admet-442	285	63	encephalomyelitis	encephalomyelitis	NOUN
admet-442	285	64	,	,	PUNCT
admet-442	285	65	j	j	PROPN
admet-442	285	66	immunol	immunol	NOUN
admet-442	285	67	176	176	NUM
admet-442	285	68	(	(	PUNCT
admet-442	285	69	2006	2006	NUM
admet-442	285	70	)	)	PUNCT
admet-442	285	71	3480	3480	NUM
admet-442	285	72	-	-	SYM
admet-442	285	73	3489	3489	NUM
admet-442	285	74	.	.	PUNCT
admet-442	286	1	[	[	X
admet-442	286	2	42	42	NUM
admet-442	286	3	]	]	PUNCT
admet-442	286	4	s.	s.	PROPN
admet-442	286	5	bodhankar	bodhankar	PROPN
admet-442	286	6	,	,	PUNCT
admet-442	286	7	d.	d.	PROPN
admet-442	286	8	galipeau	galipeau	PROPN
admet-442	286	9	,	,	PUNCT
admet-442	286	10	a.a	a.a	PROPN
admet-442	286	11	.	.	PROPN
admet-442	286	12	vandenbark	vandenbark	PROPN
admet-442	286	13	,	,	PUNCT
admet-442	286	14	h.	h.	PROPN
admet-442	286	15	offner	offner	PROPN
admet-442	286	16	.	.	PUNCT
admet-442	287	1	pd-1	pd-1	ADP
admet-442	287	2	interaction	interaction	NOUN
admet-442	287	3	with	with	ADP
admet-442	287	4	pd	pd	PROPN
admet-442	287	5	-	-	PROPN
admet-442	287	6	l1	l1	PROPN
admet-442	287	7	but	but	CCONJ
admet-442	287	8	not	not	PART
admet-442	287	9	pd	pd	NOUN
admet-442	287	10	-	-	NOUN
admet-442	287	11	l2	l2	NOUN
admet-442	287	12	on	on	ADP
admet-442	287	13	b	b	NOUN
admet-442	287	14	-	-	PUNCT
admet-442	287	15	cells	cell	NOUN
admet-442	287	16	mediates	mediate	VERB
admet-442	287	17	protective	protective	ADJ
admet-442	287	18	effects	effect	NOUN
admet-442	287	19	of	of	ADP
admet-442	287	20	estrogen	estrogen	NOUN
admet-442	287	21	against	against	ADP
admet-442	287	22	eae	eae	PROPN
admet-442	287	23	,	,	PUNCT
admet-442	287	24	j	j	PROPN
admet-442	287	25	clin	clin	PROPN
admet-442	287	26	cell	cell	PROPN
admet-442	287	27	immunol	immunol	NOUN
admet-442	287	28	4	4	NUM
admet-442	287	29	(	(	PUNCT
admet-442	287	30	2013	2013	NUM
admet-442	287	31	)	)	PUNCT
admet-442	287	32	143	143	NUM
admet-442	287	33	.	.	PUNCT
admet-442	288	1	[	[	X
admet-442	288	2	43	43	NUM
admet-442	288	3	]	]	PUNCT
admet-442	288	4	m.	m.	PROPN
admet-442	288	5	kobayashi	kobayashi	PROPN
admet-442	288	6	,	,	PUNCT
admet-442	288	7	s.	s.	PROPN
admet-442	288	8	kawano	kawano	PROPN
admet-442	288	9	,	,	PUNCT
admet-442	288	10	s.	s.	PROPN
admet-442	288	11	hatachi	hatachi	PROPN
admet-442	288	12	,	,	PUNCT
admet-442	288	13	c.	c.	PROPN
admet-442	288	14	kurimoto	kurimoto	PROPN
admet-442	288	15	,	,	PUNCT
admet-442	288	16	t.	t.	PROPN
admet-442	288	17	okazaki	okazaki	PROPN
admet-442	288	18	,	,	PUNCT
admet-442	288	19	y.	y.	PROPN
admet-442	288	20	iwai	iwai	PROPN
admet-442	288	21	,	,	PUNCT
admet-442	288	22	t.	t.	PROPN
admet-442	288	23	honjo	honjo	PROPN
admet-442	288	24	,	,	PUNCT
admet-442	288	25	y.	y.	PROPN
admet-442	288	26	tanaka	tanaka	PROPN
admet-442	288	27	,	,	PUNCT
admet-442	288	28	n.	n.	PROPN
admet-442	288	29	minato	minato	PROPN
admet-442	288	30	,	,	PUNCT
admet-442	288	31	t.	t.	PROPN
admet-442	288	32	komori	komori	PROPN
admet-442	288	33	,	,	PUNCT
admet-442	288	34	s.	s.	PROPN
admet-442	288	35	maeda	maeda	PROPN
admet-442	288	36	,	,	PUNCT
admet-442	288	37	s.	s.	PROPN
admet-442	288	38	kumagai	kumagai	PROPN
admet-442	288	39	.	.	PUNCT
admet-442	289	1	enhanced	enhance	VERB
admet-442	289	2	expression	expression	NOUN
admet-442	289	3	of	of	ADP
admet-442	289	4	programmed	program	VERB
admet-442	289	5	death-1	death-1	PROPN
admet-442	289	6	(	(	PUNCT
admet-442	289	7	pd-1)/pdl1	pd-1)/pdl1	PROPN
admet-442	289	8	in	in	ADP
admet-442	289	9	salivary	salivary	ADJ
admet-442	289	10	glands	gland	NOUN
admet-442	289	11	of	of	ADP
admet-442	289	12	patients	patient	NOUN
admet-442	289	13	with	with	ADP
admet-442	289	14	sjogren	sjogren	PROPN
admet-442	289	15	's	's	PART
admet-442	289	16	syndrome	syndrome	NOUN
admet-442	289	17	,	,	PUNCT
admet-442	289	18	j	j	PROPN
admet-442	289	19	rheumatol	rheumatol	VERB
admet-442	289	20	32	32	NUM
admet-442	289	21	(	(	PUNCT
admet-442	289	22	2005	2005	NUM
admet-442	289	23	)	)	PUNCT
admet-442	289	24	2156	2156	NUM
admet-442	289	25	-	-	SYM
admet-442	289	26	2163	2163	NUM
admet-442	289	27	.	.	PUNCT
admet-442	290	1	[	[	X
admet-442	290	2	44	44	NUM
admet-442	290	3	]	]	X
admet-442	290	4	m.f	m.f	PROPN
admet-442	290	5	.	.	PUNCT
admet-442	290	6	liu	liu	PROPN
admet-442	290	7	,	,	PUNCT
admet-442	290	8	c.t	c.t	PROPN
admet-442	290	9	.	.	PROPN
admet-442	290	10	weng	weng	PROPN
admet-442	290	11	,	,	PUNCT
admet-442	290	12	m.y	m.y	PROPN
admet-442	290	13	.	.	PROPN
admet-442	290	14	weng	weng	PROPN
admet-442	290	15	.	.	PUNCT
admet-442	291	1	variable	variable	ADJ
admet-442	291	2	increased	increase	VERB
admet-442	291	3	expression	expression	NOUN
admet-442	291	4	of	of	ADP
admet-442	291	5	program	program	NOUN
admet-442	291	6	death-1	death-1	NUM
admet-442	291	7	and	and	CCONJ
admet-442	291	8	program	program	VERB
admet-442	291	9	death-1	death-1	NUM
admet-442	291	10	ligands	ligand	NOUN
admet-442	291	11	on	on	ADP
admet-442	291	12	peripheral	peripheral	ADJ
admet-442	291	13	mononuclear	mononuclear	ADJ
admet-442	291	14	cells	cell	NOUN
admet-442	291	15	is	be	AUX
admet-442	291	16	not	not	PART
admet-442	291	17	impaired	impair	VERB
admet-442	291	18	in	in	ADP
admet-442	291	19	patients	patient	NOUN
admet-442	291	20	with	with	ADP
admet-442	291	21	systemic	systemic	ADJ
admet-442	291	22	lupus	lupus	PROPN
admet-442	291	23	erythematosus	erythematosus	PROPN
admet-442	291	24	,	,	PUNCT
admet-442	291	25	j	j	PROPN
admet-442	291	26	biomed	biome	VERB
admet-442	291	27	biotechnol	biotechnol	NOUN
admet-442	291	28	(	(	PUNCT
admet-442	291	29	2009	2009	NUM
admet-442	291	30	)	)	PUNCT
admet-442	291	31	.	.	PUNCT
admet-442	292	1	[	[	X
admet-442	292	2	45	45	NUM
admet-442	292	3	]	]	PUNCT
admet-442	292	4	t.	t.	PROPN
admet-442	292	5	kanai	kanai	PROPN
admet-442	292	6	,	,	PUNCT
admet-442	292	7	t.	t.	PROPN
admet-442	292	8	totsuka	totsuka	PROPN
admet-442	292	9	,	,	PUNCT
admet-442	292	10	k.	k.	PROPN
admet-442	292	11	uraushihara	uraushihara	PROPN
admet-442	292	12	,	,	PUNCT
admet-442	292	13	s.	s.	PROPN
admet-442	292	14	makita	makita	PROPN
admet-442	292	15	,	,	PUNCT
admet-442	292	16	t.	t.	PROPN
admet-442	292	17	nakamura	nakamura	PROPN
admet-442	292	18	,	,	PUNCT
admet-442	292	19	k.	k.	PROPN
admet-442	292	20	koganei	koganei	PROPN
admet-442	292	21	,	,	PUNCT
admet-442	292	22	t.	t.	PROPN
admet-442	292	23	fukushima	fukushima	PROPN
admet-442	292	24	,	,	PUNCT
admet-442	292	25	h.	h.	PROPN
admet-442	292	26	akiba	akiba	PROPN
admet-442	292	27	,	,	PUNCT
admet-442	292	28	h.	h.	PROPN
admet-442	292	29	yagita	yagita	PROPN
admet-442	292	30	,	,	PUNCT
admet-442	292	31	k.	k.	PROPN
admet-442	292	32	okumura	okumura	PROPN
admet-442	292	33	,	,	PUNCT
admet-442	292	34	t.	t.	PROPN
admet-442	292	35	machida	machida	PROPN
admet-442	292	36	,	,	PUNCT
admet-442	292	37	h.	h.	PROPN
admet-442	292	38	iwai	iwai	PROPN
admet-442	292	39	,	,	PUNCT
admet-442	292	40	m.	m.	NOUN
admet-442	292	41	azuma	azuma	PROPN
admet-442	292	42	,	,	PUNCT
admet-442	292	43	l.p	l.p	PROPN
admet-442	292	44	.	.	PROPN
admet-442	292	45	chen	chen	PROPN
admet-442	292	46	,	,	PUNCT
admet-442	292	47	m.	m.	PROPN
admet-442	292	48	watanabe	watanabe	PROPN
admet-442	292	49	.	.	PUNCT
admet-442	293	1	blockade	blockade	NOUN
admet-442	293	2	of	of	ADP
admet-442	293	3	b7	b7	PROPN
admet-442	293	4	-	-	PUNCT
admet-442	293	5	h1	h1	PROPN
admet-442	293	6	admet	admet	PROPN
admet-442	293	7	&	&	CCONJ
admet-442	293	8	dmpk	dmpk	PROPN
admet-442	293	9	5(3	5(3	NUM
admet-442	293	10	)	)	PUNCT
admet-442	293	11	(	(	PUNCT
admet-442	293	12	2017	2017	NUM
admet-442	293	13	)	)	PUNCT
admet-442	293	14	159	159	NUM
admet-442	293	15	-	-	SYM
admet-442	293	16	172	172	NUM
admet-442	293	17	the	the	DET
admet-442	293	18	function	function	NOUN
admet-442	293	19	and	and	CCONJ
admet-442	293	20	regulation	regulation	NOUN
admet-442	293	21	of	of	ADP
admet-442	293	22	pd	pd	PROPN
admet-442	293	23	-	-	PROPN
admet-442	293	24	l1	l1	PROPN
admet-442	293	25	in	in	ADP
admet-442	293	26	immunotherapy	immunotherapy	NOUN
admet-442	293	27	doi	doi	NOUN
admet-442	293	28	:	:	PUNCT
admet-442	293	29	10.5599	10.5599	NUM
admet-442	293	30	/	/	SYM
admet-442	293	31	admet.5.3.442	admet.5.3.442	NUM
admet-442	293	32	169	169	NUM
admet-442	293	33	suppresses	suppress	VERB
admet-442	293	34	intestinal	intestinal	ADJ
admet-442	293	35	inflammation	inflammation	NOUN
admet-442	293	36	the	the	DET
admet-442	293	37	development	development	NOUN
admet-442	293	38	of	of	ADP
admet-442	293	39	chronic	chronic	NOUN
admet-442	293	40	,	,	PUNCT
admet-442	293	41	journal	journal	NOUN
admet-442	293	42	of	of	ADP
admet-442	293	43	immunology	immunology	NOUN
admet-442	293	44	171	171	NUM
admet-442	293	45	(	(	PUNCT
admet-442	293	46	2003	2003	NUM
admet-442	293	47	)	)	PUNCT
admet-442	293	48	4156	4156	NUM
admet-442	293	49	-	-	SYM
admet-442	293	50	4163	4163	NUM
admet-442	293	51	.	.	PUNCT
admet-442	294	1	[	[	X
admet-442	294	2	46	46	NUM
admet-442	294	3	]	]	PUNCT
admet-442	294	4	z.	z.	PROPN
admet-442	294	5	xie	xie	PROPN
admet-442	294	6	,	,	PUNCT
admet-442	294	7	y.	y.	PROPN
admet-442	294	8	chen	chen	PROPN
admet-442	294	9	,	,	PUNCT
admet-442	294	10	s.	s.	PROPN
admet-442	294	11	zhao	zhao	PROPN
admet-442	294	12	,	,	PUNCT
admet-442	294	13	z.	z.	PROPN
admet-442	294	14	yang	yang	PROPN
admet-442	294	15	,	,	PUNCT
admet-442	294	16	x.	x.	PROPN
admet-442	294	17	yao	yao	PROPN
admet-442	294	18	,	,	PUNCT
admet-442	294	19	s.	s.	PROPN
admet-442	294	20	guo	guo	PROPN
admet-442	294	21	,	,	PUNCT
admet-442	294	22	c.	c.	PROPN
admet-442	294	23	yang	yang	PROPN
admet-442	294	24	,	,	PUNCT
admet-442	294	25	l.	l.	PROPN
admet-442	294	26	fei	fei	PROPN
admet-442	294	27	,	,	PUNCT
admet-442	294	28	x.	x.	PROPN
admet-442	294	29	zeng	zeng	PROPN
admet-442	294	30	,	,	PUNCT
admet-442	294	31	b.	b.	PROPN
admet-442	294	32	ni	ni	PROPN
admet-442	294	33	,	,	PUNCT
admet-442	294	34	y.	y.	PROPN
admet-442	294	35	wu	wu	PROPN
admet-442	294	36	.	.	PUNCT
admet-442	295	1	intrahepatic	intrahepatic	ADJ
admet-442	295	2	pd1	pd1	NOUN
admet-442	295	3	/	/	SYM
admet-442	295	4	pd	pd	NOUN
admet-442	295	5	-	-	PROPN
admet-442	295	6	l1	l1	PROPN
admet-442	295	7	up	up	ADP
admet-442	295	8	-	-	PUNCT
admet-442	295	9	regulation	regulation	NOUN
admet-442	295	10	closely	closely	ADV
admet-442	295	11	correlates	correlate	VERB
admet-442	295	12	with	with	ADP
admet-442	295	13	inflammation	inflammation	NOUN
admet-442	295	14	and	and	CCONJ
admet-442	295	15	virus	virus	NOUN
admet-442	295	16	replication	replication	NOUN
admet-442	295	17	in	in	ADP
admet-442	295	18	patients	patient	NOUN
admet-442	295	19	with	with	ADP
admet-442	295	20	chronic	chronic	ADJ
admet-442	295	21	hbv	hbv	NOUN
admet-442	295	22	infection	infection	NOUN
admet-442	295	23	,	,	PUNCT
admet-442	295	24	immunol	immunol	NOUN
admet-442	295	25	invest	invest	VERB
admet-442	295	26	38	38	NUM
admet-442	295	27	(	(	PUNCT
admet-442	295	28	2009	2009	NUM
admet-442	295	29	)	)	PUNCT
admet-442	295	30	624	624	NUM
admet-442	295	31	-	-	PUNCT
admet-442	295	32	638	638	NUM
admet-442	295	33	.	.	PUNCT
admet-442	296	1	[	[	X
admet-442	296	2	47	47	NUM
admet-442	296	3	]	]	PUNCT
admet-442	296	4	a.	a.	NOUN
admet-442	296	5	kassem	kassem	PROPN
admet-442	296	6	,	,	PUNCT
admet-442	296	7	a.	a.	PROPN
admet-442	296	8	schopflin	schopflin	PROPN
admet-442	296	9	,	,	PUNCT
admet-442	296	10	c.	c.	PROPN
admet-442	296	11	diaz	diaz	PROPN
admet-442	296	12	,	,	PUNCT
admet-442	296	13	w.	w.	PROPN
admet-442	296	14	weyers	weyers	PROPN
admet-442	296	15	,	,	PUNCT
admet-442	296	16	e.	e.	PROPN
admet-442	296	17	stickeler	stickeler	PROPN
admet-442	296	18	,	,	PUNCT
admet-442	296	19	m.	m.	NOUN
admet-442	296	20	werner	werner	PROPN
admet-442	296	21	,	,	PUNCT
admet-442	296	22	a.	a.	PROPN
admet-442	296	23	zur	zur	PROPN
admet-442	296	24	hausen	hausen	PROPN
admet-442	296	25	.	.	PUNCT
admet-442	296	26	frequent	frequent	ADJ
admet-442	296	27	detection	detection	NOUN
admet-442	296	28	of	of	ADP
admet-442	296	29	merkel	merkel	PROPN
admet-442	296	30	cell	cell	NOUN
admet-442	296	31	polyomavirus	polyomavirus	NOUN
admet-442	296	32	in	in	ADP
admet-442	296	33	human	human	ADJ
admet-442	296	34	merkel	merkel	PROPN
admet-442	296	35	cell	cell	NOUN
admet-442	296	36	carcinomas	carcinoma	NOUN
admet-442	296	37	and	and	CCONJ
admet-442	296	38	identification	identification	NOUN
admet-442	296	39	of	of	ADP
admet-442	296	40	a	a	DET
admet-442	296	41	unique	unique	ADJ
admet-442	296	42	deletion	deletion	NOUN
admet-442	296	43	in	in	ADP
admet-442	296	44	the	the	DET
admet-442	296	45	vp1	vp1	NOUN
admet-442	296	46	gene	gene	NOUN
admet-442	296	47	,	,	PUNCT
admet-442	296	48	cancer	cancer	NOUN
admet-442	296	49	res	re	NOUN
admet-442	296	50	68	68	NUM
admet-442	296	51	(	(	PUNCT
admet-442	296	52	2008	2008	NUM
admet-442	296	53	)	)	PUNCT
admet-442	296	54	5009	5009	NUM
admet-442	296	55	-	-	SYM
admet-442	296	56	5013	5013	NUM
admet-442	296	57	.	.	PUNCT
admet-442	297	1	[	[	X
admet-442	297	2	48	48	NUM
admet-442	297	3	]	]	SYM
admet-442	297	4	e.j	e.j	PROPN
admet-442	297	5	.	.	PROPN
admet-442	297	6	lipson	lipson	PROPN
admet-442	297	7	,	,	PUNCT
admet-442	297	8	j.g	j.g	PROPN
admet-442	297	9	.	.	PROPN
admet-442	297	10	vincent	vincent	PROPN
admet-442	297	11	,	,	PUNCT
admet-442	297	12	m.	m.	NOUN
admet-442	297	13	loyo	loyo	PROPN
admet-442	297	14	,	,	PUNCT
admet-442	297	15	l.t	l.t	PROPN
admet-442	297	16	.	.	PROPN
admet-442	297	17	kagohara	kagohara	PROPN
admet-442	297	18	,	,	PUNCT
admet-442	297	19	b.s	b.s	PROPN
admet-442	297	20	.	.	PROPN
admet-442	297	21	luber	luber	PROPN
admet-442	297	22	,	,	PUNCT
admet-442	297	23	h.	h.	PROPN
admet-442	297	24	wang	wang	PROPN
admet-442	297	25	,	,	PUNCT
admet-442	297	26	h.	h.	PROPN
admet-442	297	27	xu	xu	PROPN
admet-442	297	28	,	,	PUNCT
admet-442	297	29	s.k	s.k	PROPN
admet-442	297	30	.	.	PROPN
admet-442	297	31	nayar	nayar	PROPN
admet-442	297	32	,	,	PUNCT
admet-442	297	33	t.s	t.s	PROPN
admet-442	297	34	.	.	PROPN
admet-442	297	35	wang	wang	PROPN
admet-442	297	36	,	,	PUNCT
admet-442	297	37	d.	d.	PROPN
admet-442	297	38	sidransky	sidransky	PROPN
admet-442	297	39	,	,	PUNCT
admet-442	297	40	r.a	r.a	PROPN
admet-442	297	41	.	.	PROPN
admet-442	297	42	anders	anders	PROPN
admet-442	297	43	,	,	PUNCT
admet-442	297	44	s.l	s.l	PROPN
admet-442	297	45	.	.	PROPN
admet-442	297	46	topalian	topalian	PROPN
admet-442	297	47	,	,	PUNCT
admet-442	297	48	j.m	j.m	PROPN
admet-442	297	49	.	.	PROPN
admet-442	297	50	taube	taube	PROPN
admet-442	297	51	.	.	PUNCT
admet-442	298	1	pd	pd	PROPN
admet-442	298	2	-	-	PUNCT
admet-442	298	3	l1	l1	PROPN
admet-442	298	4	expression	expression	NOUN
admet-442	298	5	in	in	ADP
admet-442	298	6	the	the	DET
admet-442	298	7	merkel	merkel	NOUN
admet-442	298	8	cell	cell	NOUN
admet-442	298	9	carcinoma	carcinoma	NOUN
admet-442	298	10	microenvironment	microenvironment	NOUN
admet-442	298	11	:	:	PUNCT
admet-442	298	12	association	association	NOUN
admet-442	298	13	with	with	ADP
admet-442	298	14	inflammation	inflammation	NOUN
admet-442	298	15	,	,	PUNCT
admet-442	298	16	merkel	merkel	NOUN
admet-442	298	17	cell	cell	NOUN
admet-442	298	18	polyomavirus	polyomavirus	NOUN
admet-442	298	19	and	and	CCONJ
admet-442	298	20	overall	overall	ADJ
admet-442	298	21	survival	survival	NOUN
admet-442	298	22	,	,	PUNCT
admet-442	298	23	cancer	cancer	NOUN
admet-442	298	24	immunol	immunol	NOUN
admet-442	298	25	res	re	NOUN
admet-442	298	26	1	1	NUM
admet-442	298	27	(	(	PUNCT
admet-442	298	28	2013	2013	NUM
admet-442	298	29	)	)	PUNCT
admet-442	298	30	54	54	NUM
admet-442	298	31	-	-	SYM
admet-442	298	32	63	63	NUM
admet-442	298	33	.	.	PUNCT
admet-442	299	1	[	[	X
admet-442	299	2	49	49	NUM
admet-442	299	3	]	]	X
admet-442	299	4	j.k	j.k	PROPN
admet-442	299	5	.	.	PROPN
admet-442	299	6	whitmire	whitmire	PROPN
admet-442	299	7	,	,	PUNCT
admet-442	299	8	j.t	j.t	PROPN
admet-442	299	9	.	.	PROPN
admet-442	299	10	tan	tan	PROPN
admet-442	299	11	,	,	PUNCT
admet-442	299	12	j.l	j.l	PROPN
admet-442	299	13	.	.	PROPN
admet-442	299	14	whitton	whitton	PROPN
admet-442	299	15	.	.	PUNCT
admet-442	300	1	interferon	interferon	ADJ
admet-442	300	2	-	-	PUNCT
admet-442	300	3	gamma	gamma	NOUN
admet-442	300	4	acts	act	VERB
admet-442	300	5	directly	directly	ADV
admet-442	300	6	on	on	ADP
admet-442	300	7	cd8(+	cd8(+	PROPN
admet-442	300	8	)	)	PUNCT
admet-442	300	9	t	t	PROPN
admet-442	300	10	cells	cell	NOUN
admet-442	300	11	to	to	PART
admet-442	300	12	increase	increase	VERB
admet-442	300	13	their	their	PRON
admet-442	300	14	abundance	abundance	NOUN
admet-442	300	15	during	during	ADP
admet-442	300	16	virus	virus	NOUN
admet-442	300	17	infection	infection	NOUN
admet-442	300	18	,	,	PUNCT
admet-442	300	19	journal	journal	NOUN
admet-442	300	20	of	of	ADP
admet-442	300	21	experimental	experimental	ADJ
admet-442	300	22	medicine	medicine	NOUN
admet-442	300	23	201	201	NUM
admet-442	300	24	(	(	PUNCT
admet-442	300	25	2005	2005	NUM
admet-442	300	26	)	)	PUNCT
admet-442	300	27	1053	1053	NUM
admet-442	300	28	-	-	SYM
admet-442	300	29	1059	1059	NUM
admet-442	300	30	.	.	PUNCT
admet-442	301	1	[	[	X
admet-442	301	2	50	50	NUM
admet-442	301	3	]	]	PUNCT
admet-442	301	4	h.	h.	PROPN
admet-442	301	5	maier	maier	PROPN
admet-442	301	6	,	,	PUNCT
admet-442	301	7	m.	m.	NOUN
admet-442	301	8	isogawa	isogawa	PROPN
admet-442	301	9	,	,	PUNCT
admet-442	301	10	g.j	g.j	PROPN
admet-442	301	11	.	.	PROPN
admet-442	301	12	freeman	freeman	PROPN
admet-442	301	13	,	,	PUNCT
admet-442	301	14	f.v	f.v	PROPN
admet-442	301	15	.	.	PROPN
admet-442	301	16	chisari	chisari	PROPN
admet-442	301	17	.	.	PUNCT
admet-442	302	1	pd-1	pd-1	ADJ
admet-442	302	2	:	:	PUNCT
admet-442	302	3	pd	pd	ADJ
admet-442	302	4	-	-	PUNCT
admet-442	302	5	l1	l1	PROPN
admet-442	302	6	interactions	interaction	NOUN
admet-442	302	7	contribute	contribute	VERB
admet-442	302	8	to	to	ADP
admet-442	302	9	the	the	DET
admet-442	302	10	functional	functional	ADJ
admet-442	302	11	suppression	suppression	NOUN
admet-442	302	12	of	of	ADP
admet-442	302	13	virus	virus	NOUN
admet-442	302	14	-	-	PUNCT
admet-442	302	15	specific	specific	ADJ
admet-442	302	16	cd8	cd8	PROPN
admet-442	302	17	+	+	PROPN
admet-442	302	18	t	t	PROPN
admet-442	302	19	lymphocytes	lymphocyte	VERB
admet-442	302	20	in	in	ADP
admet-442	302	21	the	the	DET
admet-442	302	22	liver	liver	NOUN
admet-442	302	23	,	,	PUNCT
admet-442	302	24	j	j	PROPN
admet-442	302	25	immunol	immunol	NOUN
admet-442	302	26	178	178	NUM
admet-442	302	27	(	(	PUNCT
admet-442	302	28	2007	2007	NUM
admet-442	302	29	)	)	PUNCT
admet-442	302	30	2714	2714	NUM
admet-442	302	31	-	-	SYM
admet-442	302	32	2720	2720	NUM
admet-442	302	33	.	.	PUNCT
admet-442	303	1	[	[	X
admet-442	303	2	51	51	NUM
admet-442	303	3	]	]	X
admet-442	303	4	d.l	d.l	PROPN
admet-442	303	5	.	.	PROPN
admet-442	303	6	barber	barber	PROPN
admet-442	303	7	,	,	PUNCT
admet-442	303	8	e.j	e.j	PROPN
admet-442	303	9	.	.	PROPN
admet-442	303	10	wherry	wherry	PROPN
admet-442	303	11	,	,	PUNCT
admet-442	303	12	d.	d.	PROPN
admet-442	303	13	masopust	masopust	PROPN
admet-442	303	14	,	,	PUNCT
admet-442	303	15	b.	b.	PROPN
admet-442	303	16	zhu	zhu	PROPN
admet-442	303	17	,	,	PUNCT
admet-442	303	18	j.p	j.p	PROPN
admet-442	303	19	.	.	PROPN
admet-442	303	20	allison	allison	PROPN
admet-442	303	21	,	,	PUNCT
admet-442	303	22	a.h	a.h	PROPN
admet-442	303	23	.	.	PROPN
admet-442	303	24	sharpe	sharpe	PROPN
admet-442	303	25	,	,	PUNCT
admet-442	303	26	g.j	g.j	PROPN
admet-442	303	27	.	.	PROPN
admet-442	303	28	freeman	freeman	PROPN
admet-442	303	29	,	,	PUNCT
admet-442	303	30	r.	r.	PROPN
admet-442	303	31	ahmed	ahmed	PROPN
admet-442	303	32	.	.	PUNCT
admet-442	304	1	restoring	restore	VERB
admet-442	304	2	function	function	NOUN
admet-442	304	3	in	in	ADP
admet-442	304	4	exhausted	exhausted	ADJ
admet-442	304	5	cd8	cd8	PROPN
admet-442	304	6	t	t	PROPN
admet-442	304	7	cells	cell	NOUN
admet-442	304	8	during	during	ADP
admet-442	304	9	chronic	chronic	ADJ
admet-442	304	10	viral	viral	ADJ
admet-442	304	11	infection	infection	NOUN
admet-442	304	12	,	,	PUNCT
admet-442	304	13	nature	nature	NOUN
admet-442	304	14	439	439	NUM
admet-442	304	15	(	(	PUNCT
admet-442	304	16	2006	2006	NUM
admet-442	304	17	)	)	PUNCT
admet-442	304	18	682687	682687	NUM
admet-442	304	19	.	.	PUNCT
admet-442	305	1	[	[	X
admet-442	305	2	52	52	NUM
admet-442	305	3	]	]	PUNCT
admet-442	305	4	l.	l.	PROPN
admet-442	305	5	trautmann	trautmann	PROPN
admet-442	305	6	,	,	PUNCT
admet-442	305	7	l.	l.	PROPN
admet-442	305	8	janbazian	janbazian	PROPN
admet-442	305	9	,	,	PUNCT
admet-442	305	10	n.	n.	NOUN
admet-442	305	11	chomont	chomont	PROPN
admet-442	305	12	,	,	PUNCT
admet-442	305	13	e.a	e.a	PROPN
admet-442	305	14	.	.	PROPN
admet-442	305	15	said	say	VERB
admet-442	305	16	,	,	PUNCT
admet-442	305	17	s.	s.	PROPN
admet-442	305	18	gimmig	gimmig	PROPN
admet-442	305	19	,	,	PUNCT
admet-442	305	20	b.	b.	PROPN
admet-442	305	21	bessette	bessette	PROPN
admet-442	305	22	,	,	PUNCT
admet-442	305	23	m.r	m.r	PROPN
admet-442	305	24	.	.	PROPN
admet-442	305	25	boulassel	boulassel	PROPN
admet-442	305	26	,	,	PUNCT
admet-442	305	27	e.	e.	PROPN
admet-442	305	28	delwart	delwart	PROPN
admet-442	305	29	,	,	PUNCT
admet-442	305	30	h.	h.	PROPN
admet-442	305	31	sepulveda	sepulveda	PROPN
admet-442	305	32	,	,	PUNCT
admet-442	305	33	r.s	r.s	PROPN
admet-442	305	34	.	.	PROPN
admet-442	305	35	balderas	balderas	PROPN
admet-442	305	36	,	,	PUNCT
admet-442	305	37	j.p	j.p	PROPN
admet-442	305	38	.	.	PROPN
admet-442	305	39	routy	routy	PROPN
admet-442	305	40	,	,	PUNCT
admet-442	305	41	e.k	e.k	PROPN
admet-442	305	42	.	.	PROPN
admet-442	305	43	haddad	haddad	PROPN
admet-442	305	44	,	,	PUNCT
admet-442	305	45	r.p	r.p	PROPN
admet-442	305	46	.	.	PROPN
admet-442	305	47	sekaly	sekaly	PROPN
admet-442	305	48	.	.	PUNCT
admet-442	306	1	upregulation	upregulation	NOUN
admet-442	306	2	of	of	ADP
admet-442	306	3	pd-1	pd-1	ADJ
admet-442	306	4	expression	expression	NOUN
admet-442	306	5	on	on	ADP
admet-442	306	6	hiv	hiv	PROPN
admet-442	306	7	-	-	PUNCT
admet-442	306	8	specific	specific	ADJ
admet-442	306	9	cd8(+	cd8(+	PROPN
admet-442	306	10	)	)	PUNCT
admet-442	306	11	t	t	PROPN
admet-442	306	12	cells	cell	NOUN
admet-442	306	13	leads	lead	VERB
admet-442	306	14	to	to	ADP
admet-442	306	15	reversible	reversible	ADJ
admet-442	306	16	immune	immune	ADJ
admet-442	306	17	dysfunction	dysfunction	NOUN
admet-442	306	18	(	(	PUNCT
admet-442	306	19	vol	vol	NOUN
admet-442	306	20	12	12	NUM
admet-442	306	21	,	,	PUNCT
admet-442	306	22	1198	1198	NUM
admet-442	306	23	,	,	PUNCT
admet-442	306	24	2006	2006	NUM
admet-442	306	25	)	)	PUNCT
admet-442	306	26	,	,	PUNCT
admet-442	306	27	nature	nature	NOUN
admet-442	306	28	medicine	medicine	NOUN
admet-442	306	29	12	12	NUM
admet-442	306	30	(	(	PUNCT
admet-442	306	31	2006	2006	NUM
admet-442	306	32	)	)	PUNCT
admet-442	306	33	1329	1329	NUM
admet-442	306	34	-	-	SYM
admet-442	306	35	1329	1329	NUM
admet-442	306	36	.	.	PUNCT
admet-442	307	1	[	[	X
admet-442	307	2	53	53	NUM
admet-442	307	3	]	]	PUNCT
admet-442	307	4	s.	s.	PROPN
admet-442	307	5	urbani	urbani	PROPN
admet-442	307	6	,	,	PUNCT
admet-442	307	7	b.	b.	PROPN
admet-442	307	8	amadei	amadei	PROPN
admet-442	307	9	,	,	PUNCT
admet-442	307	10	d.	d.	PROPN
admet-442	307	11	tola	tola	PROPN
admet-442	307	12	,	,	PUNCT
admet-442	307	13	g.	g.	PROPN
admet-442	307	14	pedrazzi	pedrazzi	PROPN
admet-442	307	15	,	,	PUNCT
admet-442	307	16	l.	l.	PROPN
admet-442	307	17	sacchelli	sacchelli	PROPN
admet-442	307	18	,	,	PUNCT
admet-442	307	19	m.c	m.c	PROPN
admet-442	307	20	.	.	PROPN
admet-442	307	21	cavallo	cavallo	PROPN
admet-442	307	22	,	,	PUNCT
admet-442	307	23	a.	a.	NOUN
admet-442	307	24	orlandini	orlandini	PROPN
admet-442	307	25	,	,	PUNCT
admet-442	307	26	g.	g.	PROPN
admet-442	307	27	missale	missale	PROPN
admet-442	307	28	,	,	PUNCT
admet-442	307	29	c.	c.	PROPN
admet-442	307	30	ferrari	ferrari	PROPN
admet-442	307	31	.	.	PUNCT
admet-442	308	1	restoration	restoration	NOUN
admet-442	308	2	of	of	ADP
admet-442	308	3	hcv	hcv	NOUN
admet-442	308	4	-	-	PUNCT
admet-442	308	5	specific	specific	ADJ
admet-442	308	6	t	t	NOUN
admet-442	308	7	cell	cell	NOUN
admet-442	308	8	functions	function	NOUN
admet-442	308	9	by	by	ADP
admet-442	308	10	pd-1	pd-1	NOUN
admet-442	308	11	/	/	SYM
admet-442	308	12	pd	pd	ADJ
admet-442	308	13	-	-	PUNCT
admet-442	308	14	l1	l1	PROPN
admet-442	308	15	blockade	blockade	NOUN
admet-442	308	16	in	in	ADP
admet-442	308	17	hcv	hcv	NOUN
admet-442	308	18	infection	infection	NOUN
admet-442	308	19	:	:	PUNCT
admet-442	308	20	effect	effect	NOUN
admet-442	308	21	of	of	ADP
admet-442	308	22	viremia	viremia	NOUN
admet-442	308	23	levels	level	NOUN
admet-442	308	24	and	and	CCONJ
admet-442	308	25	antiviral	antiviral	ADJ
admet-442	308	26	treatment	treatment	NOUN
admet-442	308	27	,	,	PUNCT
admet-442	308	28	j	j	PROPN
admet-442	308	29	hepatol	hepatol	ADJ
admet-442	308	30	48	48	NUM
admet-442	308	31	(	(	PUNCT
admet-442	308	32	2008	2008	NUM
admet-442	308	33	)	)	PUNCT
admet-442	308	34	548	548	NUM
admet-442	308	35	-	-	SYM
admet-442	308	36	558	558	NUM
admet-442	308	37	.	.	PUNCT
admet-442	309	1	[	[	X
admet-442	309	2	54	54	NUM
admet-442	309	3	]	]	X
admet-442	309	4	b.b	b.b	PROPN
admet-442	309	5	.	.	PROPN
admet-442	309	6	dai	dai	PROPN
admet-442	309	7	,	,	PUNCT
admet-442	309	8	l.	l.	PROPN
admet-442	309	9	xiao	xiao	PROPN
admet-442	309	10	,	,	PUNCT
admet-442	309	11	p.d	p.d	PROPN
admet-442	309	12	.	.	PROPN
admet-442	309	13	bryson	bryson	PROPN
admet-442	309	14	,	,	PUNCT
admet-442	309	15	j.x	j.x	PROPN
admet-442	309	16	.	.	PROPN
admet-442	309	17	fang	fang	PROPN
admet-442	309	18	,	,	PUNCT
admet-442	309	19	p.	p.	PROPN
admet-442	309	20	wang	wang	PROPN
admet-442	309	21	.	.	PUNCT
admet-442	310	1	pd-1	pd-1	ADP
admet-442	310	2	/	/	SYM
admet-442	310	3	pd	pd	ADJ
admet-442	310	4	-	-	PUNCT
admet-442	310	5	l1	l1	PROPN
admet-442	310	6	blockade	blockade	NOUN
admet-442	310	7	can	can	AUX
admet-442	310	8	enhance	enhance	VERB
admet-442	310	9	hiv-1	hiv-1	X
admet-442	310	10	gagspecific	gagspecific	PROPN
admet-442	310	11	t	t	NOUN
admet-442	310	12	cell	cell	NOUN
admet-442	310	13	immunity	immunity	NOUN
admet-442	310	14	elicited	elicit	VERB
admet-442	310	15	by	by	ADP
admet-442	310	16	dendritic	dendritic	ADJ
admet-442	310	17	cell	cell	NOUN
admet-442	310	18	-	-	PUNCT
admet-442	310	19	directed	direct	VERB
admet-442	310	20	lentiviral	lentiviral	ADJ
admet-442	310	21	vaccines	vaccine	NOUN
admet-442	310	22	,	,	PUNCT
admet-442	310	23	mol	mol	ADP
admet-442	310	24	ther	ther	ADV
admet-442	310	25	20	20	NUM
admet-442	310	26	(	(	PUNCT
admet-442	310	27	2012	2012	NUM
admet-442	310	28	)	)	PUNCT
admet-442	310	29	1800	1800	NUM
admet-442	310	30	-	-	SYM
admet-442	310	31	1809	1809	NUM
admet-442	310	32	.	.	PUNCT
admet-442	311	1	[	[	X
admet-442	311	2	55	55	NUM
admet-442	311	3	]	]	SYM
admet-442	311	4	s.y	s.y	PROPN
admet-442	311	5	.	.	PUNCT
admet-442	312	1	liu	liu	PROPN
admet-442	312	2	,	,	PUNCT
admet-442	312	3	y.l	y.l	PROPN
admet-442	312	4	.	.	PROPN
admet-442	312	5	wu	wu	PROPN
admet-442	312	6	.	.	PUNCT
admet-442	313	1	ongoing	ongoing	ADJ
admet-442	313	2	clinical	clinical	ADJ
admet-442	313	3	trials	trial	NOUN
admet-442	313	4	of	of	ADP
admet-442	313	5	pd-1	pd-1	ADJ
admet-442	313	6	and	and	CCONJ
admet-442	313	7	pd	pd	PROPN
admet-442	313	8	-	-	PUNCT
admet-442	313	9	l1	l1	PROPN
admet-442	313	10	inhibitors	inhibitor	NOUN
admet-442	313	11	for	for	ADP
admet-442	313	12	lung	lung	NOUN
admet-442	313	13	cancer	cancer	NOUN
admet-442	313	14	in	in	ADP
admet-442	313	15	china	china	PROPN
admet-442	313	16	,	,	PUNCT
admet-442	313	17	j	j	PROPN
admet-442	313	18	hematol	hematol	NOUN
admet-442	313	19	oncol	oncol	ADJ
admet-442	313	20	10	10	NUM
admet-442	313	21	(	(	PUNCT
admet-442	313	22	2017	2017	NUM
admet-442	313	23	)	)	PUNCT
admet-442	313	24	136	136	NUM
admet-442	313	25	.	.	PUNCT
admet-442	314	1	[	[	X
admet-442	314	2	56	56	NUM
admet-442	314	3	]	]	X
admet-442	314	4	a.i	a.i	PROPN
admet-442	314	5	.	.	PROPN
admet-442	314	6	daud	daud	PROPN
admet-442	314	7	,	,	PUNCT
admet-442	314	8	k.	k.	PROPN
admet-442	314	9	loo	loo	PROPN
admet-442	314	10	,	,	PUNCT
admet-442	314	11	m.l	m.l	PROPN
admet-442	314	12	.	.	PROPN
admet-442	314	13	pauli	pauli	PROPN
admet-442	314	14	,	,	PUNCT
admet-442	314	15	r.	r.	PROPN
admet-442	314	16	sanchez	sanchez	PROPN
admet-442	314	17	-	-	PUNCT
admet-442	314	18	rodriguez	rodriguez	PROPN
admet-442	314	19	,	,	PUNCT
admet-442	314	20	p.m.	p.m.	NOUN
admet-442	314	21	sandoval	sandoval	PROPN
admet-442	314	22	,	,	PUNCT
admet-442	314	23	k.	k.	PROPN
admet-442	314	24	taravati	taravati	PROPN
admet-442	314	25	,	,	PUNCT
admet-442	314	26	k.	k.	PROPN
admet-442	314	27	tsai	tsai	PROPN
admet-442	314	28	,	,	PUNCT
admet-442	314	29	a.	a.	NOUN
admet-442	314	30	nosrati	nosrati	PROPN
admet-442	314	31	,	,	PUNCT
admet-442	314	32	l.	l.	PROPN
admet-442	314	33	nardo	nardo	PROPN
admet-442	314	34	,	,	PUNCT
admet-442	314	35	m.d	m.d	PROPN
admet-442	314	36	.	.	PROPN
admet-442	314	37	alvarado	alvarado	PROPN
admet-442	314	38	,	,	PUNCT
admet-442	314	39	a.p	a.p	PROPN
admet-442	314	40	.	.	PROPN
admet-442	314	41	algazi	algazi	PROPN
admet-442	314	42	,	,	PUNCT
admet-442	314	43	m.h	m.h	PROPN
admet-442	314	44	.	.	PROPN
admet-442	314	45	pampaloni	pampaloni	NOUN
admet-442	314	46	,	,	PUNCT
admet-442	314	47	i.v	i.v	PROPN
admet-442	314	48	.	.	PUNCT
admet-442	315	1	lobach	lobach	PROPN
admet-442	315	2	,	,	PUNCT
admet-442	315	3	j.	j.	PROPN
admet-442	315	4	hwang	hwang	PROPN
admet-442	315	5	,	,	PUNCT
admet-442	315	6	r.h	r.h	PROPN
admet-442	315	7	.	.	PROPN
admet-442	315	8	pierce	pierce	PROPN
admet-442	315	9	,	,	PUNCT
admet-442	315	10	i.k	i.k	PROPN
admet-442	315	11	.	.	PROPN
admet-442	315	12	gratz	gratz	PROPN
admet-442	315	13	,	,	PUNCT
admet-442	315	14	m.f	m.f	PROPN
admet-442	315	15	.	.	PROPN
admet-442	315	16	krummel	krummel	PROPN
admet-442	315	17	,	,	PUNCT
admet-442	315	18	m.d	m.d	PROPN
admet-442	315	19	.	.	PROPN
admet-442	315	20	rosenblum	rosenblum	PROPN
admet-442	315	21	.	.	PUNCT
admet-442	316	1	tumor	tumor	PROPN
admet-442	316	2	immune	immune	ADJ
admet-442	316	3	profiling	profiling	NOUN
admet-442	316	4	predicts	predict	NOUN
admet-442	316	5	response	response	NOUN
admet-442	316	6	to	to	ADP
admet-442	316	7	anti	anti	ADJ
admet-442	316	8	-	-	ADJ
admet-442	316	9	pd-1	pd-1	ADJ
admet-442	316	10	therapy	therapy	NOUN
admet-442	316	11	in	in	ADP
admet-442	316	12	human	human	ADJ
admet-442	316	13	melanoma	melanoma	NOUN
admet-442	316	14	,	,	PUNCT
admet-442	316	15	j	j	PROPN
admet-442	316	16	clin	clin	PROPN
admet-442	316	17	invest	invest	VERB
admet-442	316	18	126	126	NUM
admet-442	316	19	(	(	PUNCT
admet-442	316	20	2016	2016	NUM
admet-442	316	21	)	)	PUNCT
admet-442	316	22	3447	3447	NUM
admet-442	316	23	-	-	SYM
admet-442	316	24	3452	3452	NUM
admet-442	316	25	.	.	PUNCT
admet-442	317	1	[	[	X
admet-442	317	2	57	57	NUM
admet-442	317	3	]	]	X
admet-442	317	4	n.h	n.h	PROPN
admet-442	317	5	.	.	PUNCT
admet-442	317	6	segal	segal	PROPN
admet-442	317	7	,	,	PUNCT
admet-442	317	8	s.h.i	s.h.i	ADV
admet-442	317	9	.	.	PUNCT
admet-442	318	1	ou	ou	PROPN
admet-442	318	2	,	,	PUNCT
admet-442	318	3	a.s	a.s	PROPN
admet-442	318	4	.	.	PROPN
admet-442	318	5	balmanoukian	balmanoukian	PROPN
admet-442	318	6	,	,	PUNCT
admet-442	318	7	m.g	m.g	PROPN
admet-442	318	8	.	.	PROPN
admet-442	318	9	fury	fury	NOUN
admet-442	318	10	,	,	PUNCT
admet-442	318	11	e.	e.	PROPN
admet-442	318	12	massarelli	massarelli	PROPN
admet-442	318	13	,	,	PUNCT
admet-442	318	14	j.r	j.r	PROPN
admet-442	318	15	.	.	PROPN
admet-442	318	16	brahmer	brahmer	PROPN
admet-442	318	17	,	,	PUNCT
admet-442	318	18	j.	j.	PROPN
admet-442	318	19	weiss	weiss	PROPN
admet-442	318	20	,	,	PUNCT
admet-442	318	21	p.	p.	PROPN
admet-442	318	22	schoffski	schoffski	PROPN
admet-442	318	23	,	,	PUNCT
admet-442	318	24	s.j	s.j	PROPN
admet-442	318	25	.	.	PROPN
admet-442	318	26	antonia	antonia	PROPN
admet-442	318	27	,	,	PUNCT
admet-442	318	28	c.	c.	PROPN
admet-442	318	29	massard	massard	PROPN
admet-442	318	30	,	,	PUNCT
admet-442	318	31	d.p	d.p	PROPN
admet-442	318	32	.	.	PROPN
admet-442	318	33	zandberg	zandberg	PROPN
admet-442	318	34	,	,	PUNCT
admet-442	318	35	s.	s.	PROPN
admet-442	318	36	khleif	khleif	PROPN
admet-442	318	37	,	,	PUNCT
admet-442	318	38	x.	x.	PROPN
admet-442	318	39	li	li	PROPN
admet-442	318	40	,	,	PUNCT
admet-442	318	41	m.	m.	NOUN
admet-442	318	42	rebelatto	rebelatto	PROPN
admet-442	318	43	,	,	PUNCT
admet-442	318	44	k.	k.	PROPN
admet-442	318	45	steele	steele	PROPN
admet-442	318	46	,	,	PUNCT
admet-442	318	47	p.b	p.b	PROPN
admet-442	318	48	.	.	PROPN
admet-442	318	49	robbins	robbins	PROPN
admet-442	318	50	,	,	PUNCT
admet-442	318	51	j.a	j.a	PROPN
admet-442	318	52	.	.	PROPN
admet-442	318	53	blake	blake	PROPN
admet-442	318	54	-	-	PUNCT
admet-442	318	55	haskins	haskins	PROPN
admet-442	318	56	,	,	PUNCT
admet-442	318	57	m.o	m.o	PROPN
admet-442	318	58	.	.	PROPN
admet-442	318	59	butler	butler	PROPN
admet-442	318	60	.	.	PUNCT
admet-442	319	1	safety	safety	NOUN
admet-442	319	2	and	and	CCONJ
admet-442	319	3	efficacy	efficacy	NOUN
admet-442	319	4	of	of	ADP
admet-442	319	5	medi4736	medi4736	PROPN
admet-442	319	6	,	,	PUNCT
admet-442	319	7	an	an	DET
admet-442	319	8	anti	anti	ADJ
admet-442	319	9	-	-	ADJ
admet-442	319	10	pd	pd	ADJ
admet-442	319	11	-	-	PUNCT
admet-442	319	12	l1	l1	PROPN
admet-442	319	13	antibody	antibody	NOUN
admet-442	319	14	,	,	PUNCT
admet-442	319	15	in	in	ADP
admet-442	319	16	patients	patient	NOUN
admet-442	319	17	from	from	ADP
admet-442	319	18	a	a	DET
admet-442	319	19	squamous	squamous	ADJ
admet-442	319	20	cell	cell	NOUN
admet-442	319	21	carcinoma	carcinoma	NOUN
admet-442	319	22	of	of	ADP
admet-442	319	23	the	the	DET
admet-442	319	24	head	head	NOUN
admet-442	319	25	and	and	CCONJ
admet-442	319	26	neck	neck	NOUN
admet-442	319	27	(	(	PUNCT
admet-442	319	28	scchn	scchn	NOUN
admet-442	319	29	)	)	PUNCT
admet-442	319	30	expansion	expansion	NOUN
admet-442	319	31	cohort	cohort	NOUN
admet-442	319	32	.	.	PUNCT
admet-442	319	33	,	,	PUNCT
admet-442	320	1	j	j	PROPN
admet-442	320	2	clin	clin	PROPN
admet-442	320	3	oncol	oncol	PROPN
admet-442	320	4	33	33	NUM
admet-442	320	5	(	(	PUNCT
admet-442	320	6	2015	2015	NUM
admet-442	320	7	)	)	PUNCT
admet-442	320	8	.	.	PUNCT
admet-442	321	1	[	[	X
admet-442	321	2	58	58	NUM
admet-442	321	3	]	]	X
admet-442	321	4	n.j	n.j	PROPN
admet-442	321	5	.	.	PROPN
admet-442	321	6	llosa	llosa	PROPN
admet-442	321	7	,	,	PUNCT
admet-442	321	8	m.	m.	NOUN
admet-442	321	9	cruise	cruise	PROPN
admet-442	321	10	,	,	PUNCT
admet-442	321	11	a.	a.	PROPN
admet-442	321	12	tam	tam	PROPN
admet-442	321	13	,	,	PUNCT
admet-442	321	14	e.c	e.c	PROPN
admet-442	321	15	.	.	PROPN
admet-442	321	16	wicks	wick	NOUN
admet-442	321	17	,	,	PUNCT
admet-442	321	18	e.m	e.m	PROPN
admet-442	321	19	.	.	NOUN
admet-442	321	20	hechenbleikner	hechenbleikner	NOUN
admet-442	321	21	,	,	PUNCT
admet-442	321	22	j.m	j.m	PROPN
admet-442	321	23	.	.	PROPN
admet-442	321	24	taube	taube	PROPN
admet-442	321	25	,	,	PUNCT
admet-442	321	26	r.l	r.l	PROPN
admet-442	321	27	.	.	PROPN
admet-442	321	28	blosser	blosser	PROPN
admet-442	321	29	,	,	PUNCT
admet-442	321	30	h.n	h.n	PROPN
admet-442	321	31	.	.	PROPN
admet-442	321	32	fan	fan	PROPN
admet-442	321	33	,	,	PUNCT
admet-442	321	34	h.	h.	PROPN
admet-442	321	35	wang	wang	PROPN
admet-442	321	36	,	,	PUNCT
admet-442	321	37	b.s	b.s	PROPN
admet-442	321	38	.	.	PROPN
admet-442	321	39	luber	luber	PROPN
admet-442	321	40	,	,	PUNCT
admet-442	321	41	m.	m.	PROPN
admet-442	321	42	zhang	zhang	PROPN
admet-442	321	43	,	,	PUNCT
admet-442	321	44	n.	n.	PROPN
admet-442	321	45	papadopoulos	papadopoulos	PROPN
admet-442	321	46	,	,	PUNCT
admet-442	321	47	k.w	k.w	PROPN
admet-442	321	48	.	.	PROPN
admet-442	321	49	kinzler	kinzler	PROPN
admet-442	321	50	,	,	PUNCT
admet-442	321	51	b.	b.	PROPN
admet-442	321	52	vogelstein	vogelstein	PROPN
admet-442	321	53	,	,	PUNCT
admet-442	321	54	c.l	c.l	PROPN
admet-442	321	55	.	.	PROPN
admet-442	321	56	sears	sears	PROPN
admet-442	321	57	,	,	PUNCT
admet-442	321	58	r.a	r.a	PROPN
admet-442	321	59	.	.	PROPN
admet-442	321	60	anders	anders	PROPN
admet-442	321	61	,	,	PUNCT
admet-442	321	62	d.m	d.m	PROPN
admet-442	321	63	.	.	PROPN
admet-442	321	64	pardoll	pardoll	PROPN
admet-442	321	65	,	,	PUNCT
admet-442	321	66	f.	f.	PROPN
admet-442	321	67	housseau	housseau	PROPN
admet-442	321	68	.	.	PUNCT
admet-442	322	1	the	the	DET
admet-442	322	2	vigorous	vigorous	ADJ
admet-442	322	3	immune	immune	ADJ
admet-442	322	4	microenvironment	microenvironment	NOUN
admet-442	322	5	of	of	ADP
admet-442	322	6	microsatellite	microsatellite	ADJ
admet-442	322	7	instable	instable	ADJ
admet-442	322	8	colon	colon	NOUN
admet-442	322	9	cancer	cancer	NOUN
admet-442	322	10	is	be	AUX
admet-442	322	11	balanced	balance	VERB
admet-442	322	12	by	by	ADP
admet-442	322	13	multiple	multiple	ADJ
admet-442	322	14	counter	counter	ADJ
admet-442	322	15	-	-	ADJ
admet-442	322	16	inhibitory	inhibitory	ADJ
admet-442	322	17	checkpoints	checkpoint	NOUN
admet-442	322	18	,	,	PUNCT
admet-442	322	19	cancer	cancer	NOUN
admet-442	322	20	discov	discov	NOUN
admet-442	322	21	5	5	NUM
admet-442	322	22	(	(	PUNCT
admet-442	322	23	2015	2015	NUM
admet-442	322	24	)	)	PUNCT
admet-442	322	25	4351	4351	NUM
admet-442	322	26	.	.	PUNCT
admet-442	323	1	[	[	X
admet-442	323	2	59	59	NUM
admet-442	323	3	]	]	X
admet-442	323	4	d.	d.	PROPN
admet-442	323	5	liu	liu	PROPN
admet-442	323	6	,	,	PUNCT
admet-442	323	7	s.	s.	PROPN
admet-442	323	8	wang	wang	PROPN
admet-442	323	9	,	,	PUNCT
admet-442	323	10	w.	w.	PROPN
admet-442	323	11	bindeman	bindeman	PROPN
admet-442	323	12	.	.	PUNCT
admet-442	324	1	clinical	clinical	ADJ
admet-442	324	2	applications	application	NOUN
admet-442	324	3	of	of	ADP
admet-442	324	4	pd	pd	PROPN
admet-442	324	5	-	-	PROPN
admet-442	324	6	l1	l1	PROPN
admet-442	324	7	bioassays	bioassay	NOUN
admet-442	324	8	for	for	ADP
admet-442	324	9	cancer	cancer	NOUN
admet-442	324	10	immunotherapy	immunotherapy	NOUN
admet-442	324	11	,	,	PUNCT
admet-442	324	12	j	j	PROPN
admet-442	324	13	hematol	hematol	NOUN
admet-442	324	14	oncol	oncol	ADJ
admet-442	324	15	10	10	NUM
admet-442	324	16	(	(	PUNCT
admet-442	324	17	2017	2017	NUM
admet-442	324	18	)	)	PUNCT
admet-442	324	19	110	110	NUM
admet-442	324	20	.	.	PUNCT
admet-442	325	1	[	[	X
admet-442	325	2	60	60	NUM
admet-442	325	3	]	]	PUNCT
admet-442	325	4	j.	j.	PROPN
admet-442	325	5	chen	chen	PROPN
admet-442	325	6	,	,	PUNCT
admet-442	325	7	c.c	c.c	PROPN
admet-442	325	8	.	.	PROPN
admet-442	325	9	jiang	jiang	PROPN
admet-442	325	10	,	,	PUNCT
admet-442	325	11	l.	l.	PROPN
admet-442	325	12	jin	jin	PROPN
admet-442	325	13	,	,	PUNCT
admet-442	325	14	x.d	x.d	PROPN
admet-442	325	15	.	.	PROPN
admet-442	325	16	zhang	zhang	PROPN
admet-442	325	17	.	.	PUNCT
admet-442	325	18	regulation	regulation	NOUN
admet-442	325	19	of	of	ADP
admet-442	325	20	pd	pd	PROPN
admet-442	325	21	-	-	PROPN
admet-442	325	22	l1	l1	PROPN
admet-442	325	23	:	:	PUNCT
admet-442	325	24	a	a	DET
admet-442	325	25	novel	novel	ADJ
admet-442	325	26	role	role	NOUN
admet-442	325	27	of	of	ADP
admet-442	325	28	pro	pro	ADJ
admet-442	325	29	-	-	ADJ
admet-442	325	30	survival	survival	ADJ
admet-442	325	31	signalling	signal	VERB
admet-442	325	32	in	in	ADP
admet-442	325	33	cancer	cancer	NOUN
admet-442	325	34	,	,	PUNCT
admet-442	325	35	ann	ann	PROPN
admet-442	325	36	oncol	oncol	ADJ
admet-442	325	37	27	27	NUM
admet-442	325	38	(	(	PUNCT
admet-442	325	39	2016	2016	NUM
admet-442	325	40	)	)	PUNCT
admet-442	325	41	409	409	NUM
admet-442	325	42	-	-	SYM
admet-442	325	43	416	416	NUM
admet-442	325	44	.	.	PUNCT
admet-442	326	1	guo	guo	PROPN
admet-442	326	2	,	,	PUNCT
admet-442	326	3	lin	lin	PROPN
admet-442	326	4	and	and	CCONJ
admet-442	326	5	kwok	kwok	PROPN
admet-442	326	6	admet	admet	PROPN
admet-442	326	7	&	&	CCONJ
admet-442	326	8	dmpk	dmpk	PROPN
admet-442	326	9	5(3	5(3	NUM
admet-442	326	10	)	)	PUNCT
admet-442	326	11	(	(	PUNCT
admet-442	326	12	2017	2017	NUM
admet-442	326	13	)	)	PUNCT
admet-442	326	14	159	159	NUM
admet-442	326	15	-	-	SYM
admet-442	326	16	172	172	NUM
admet-442	326	17	170	170	NUM
admet-442	326	18	[	[	X
admet-442	326	19	61	61	NUM
admet-442	326	20	]	]	X
admet-442	326	21	n.	n.	PROPN
admet-442	326	22	chen	chen	PROPN
admet-442	326	23	,	,	PUNCT
admet-442	326	24	w.f	w.f	PROPN
admet-442	326	25	.	.	PROPN
admet-442	326	26	fang	fang	PROPN
admet-442	326	27	,	,	PUNCT
admet-442	326	28	j.h	j.h	PROPN
admet-442	326	29	.	.	PROPN
admet-442	326	30	zhan	zhan	PROPN
admet-442	326	31	,	,	PUNCT
admet-442	326	32	s.d	s.d	PROPN
admet-442	326	33	.	.	PROPN
admet-442	326	34	hong	hong	PROPN
admet-442	326	35	,	,	PUNCT
admet-442	326	36	y.n	y.n	PROPN
admet-442	326	37	.	.	PROPN
admet-442	326	38	tang	tang	PROPN
admet-442	326	39	,	,	PUNCT
admet-442	326	40	s.y	s.y	PROPN
admet-442	326	41	.	.	PROPN
admet-442	326	42	kang	kang	PROPN
admet-442	326	43	,	,	PUNCT
admet-442	326	44	y.x	y.x	PROPN
admet-442	326	45	.	.	PROPN
admet-442	326	46	zhang	zhang	PROPN
admet-442	326	47	,	,	PUNCT
admet-442	326	48	x.b	x.b	PROPN
admet-442	326	49	.	.	PROPN
admet-442	327	1	he	he	PRON
admet-442	327	2	,	,	PUNCT
admet-442	327	3	t.	t.	PROPN
admet-442	327	4	zhou	zhou	PROPN
admet-442	327	5	,	,	PUNCT
admet-442	327	6	t.	t.	PROPN
admet-442	327	7	qin	qin	PROPN
admet-442	327	8	,	,	PUNCT
admet-442	327	9	y.	y.	PROPN
admet-442	327	10	huang	huang	PROPN
admet-442	327	11	,	,	PUNCT
admet-442	327	12	x.p	x.p	PROPN
admet-442	327	13	.	.	PROPN
admet-442	327	14	yi	yi	PROPN
admet-442	327	15	,	,	PUNCT
admet-442	327	16	l.	l.	PROPN
admet-442	327	17	zhang	zhang	PROPN
admet-442	327	18	.	.	PUNCT
admet-442	328	1	upregulation	upregulation	NOUN
admet-442	328	2	of	of	ADP
admet-442	328	3	pd	pd	PROPN
admet-442	328	4	-	-	PROPN
admet-442	328	5	l1	l1	PROPN
admet-442	328	6	by	by	ADP
admet-442	328	7	egfr	egfr	ADJ
admet-442	328	8	activation	activation	NOUN
admet-442	328	9	mediates	mediate	VERB
admet-442	328	10	the	the	DET
admet-442	328	11	immune	immune	ADJ
admet-442	328	12	escape	escape	NOUN
admet-442	328	13	in	in	ADP
admet-442	328	14	egfr	egfr	NOUN
admet-442	328	15	-	-	PUNCT
admet-442	328	16	driven	drive	VERB
admet-442	328	17	nsclc	nsclc	NOUN
admet-442	328	18	implication	implication	NOUN
admet-442	328	19	for	for	ADP
admet-442	328	20	optional	optional	ADJ
admet-442	328	21	immune	immune	ADJ
admet-442	328	22	targeted	target	VERB
admet-442	328	23	therapy	therapy	NOUN
admet-442	328	24	for	for	ADP
admet-442	328	25	nsclc	nsclc	NOUN
admet-442	328	26	patients	patient	NOUN
admet-442	328	27	with	with	ADP
admet-442	328	28	egfr	egfr	ADJ
admet-442	328	29	mutation	mutation	NOUN
admet-442	328	30	,	,	PUNCT
admet-442	328	31	j	j	PROPN
admet-442	328	32	thorac	thorac	NOUN
admet-442	328	33	oncol	oncol	ADJ
admet-442	328	34	10	10	NUM
admet-442	328	35	(	(	PUNCT
admet-442	328	36	2015	2015	NUM
admet-442	328	37	)	)	PUNCT
admet-442	328	38	910	910	NUM
admet-442	328	39	-	-	SYM
admet-442	328	40	923	923	NUM
admet-442	328	41	.	.	PUNCT
admet-442	329	1	[	[	X
admet-442	329	2	62	62	NUM
admet-442	329	3	]	]	PUNCT
admet-442	329	4	h.	h.	PROPN
admet-442	329	5	dong	dong	PROPN
admet-442	329	6	,	,	PUNCT
admet-442	329	7	g.	g.	PROPN
admet-442	329	8	zhu	zhu	PROPN
admet-442	329	9	,	,	PUNCT
admet-442	329	10	k.	k.	PROPN
admet-442	329	11	tamada	tamada	PROPN
admet-442	329	12	,	,	PUNCT
admet-442	329	13	l.	l.	PROPN
admet-442	329	14	chen	chen	PROPN
admet-442	329	15	.	.	PUNCT
admet-442	330	1	b7	b7	PROPN
admet-442	330	2	-	-	PUNCT
admet-442	330	3	h1	h1	PROPN
admet-442	330	4	,	,	PUNCT
admet-442	330	5	a	a	DET
admet-442	330	6	third	third	ADJ
admet-442	330	7	member	member	NOUN
admet-442	330	8	of	of	ADP
admet-442	330	9	the	the	DET
admet-442	330	10	b7	b7	PROPN
admet-442	330	11	family	family	NOUN
admet-442	330	12	,	,	PUNCT
admet-442	330	13	co	co	VERB
admet-442	330	14	-	-	NOUN
admet-442	330	15	stimulates	stimulate	NOUN
admet-442	330	16	t	t	NOUN
admet-442	330	17	-	-	PUNCT
admet-442	330	18	cell	cell	NOUN
admet-442	330	19	proliferation	proliferation	NOUN
admet-442	330	20	and	and	CCONJ
admet-442	330	21	interleukin-10	interleukin-10	PROPN
admet-442	330	22	secretion	secretion	NOUN
admet-442	330	23	,	,	PUNCT
admet-442	330	24	nat	nat	PROPN
admet-442	330	25	med	me	VERB
admet-442	330	26	5	5	NUM
admet-442	330	27	(	(	PUNCT
admet-442	330	28	1999	1999	NUM
admet-442	330	29	)	)	PUNCT
admet-442	330	30	1365	1365	NUM
admet-442	330	31	-	-	SYM
admet-442	330	32	1369	1369	NUM
admet-442	330	33	.	.	PUNCT
admet-442	331	1	[	[	X
admet-442	331	2	63	63	NUM
admet-442	331	3	]	]	X
admet-442	331	4	g.j	g.j	PROPN
admet-442	331	5	.	.	PROPN
admet-442	331	6	freeman	freeman	PROPN
admet-442	331	7	,	,	PUNCT
admet-442	331	8	a.j	a.j	PROPN
admet-442	331	9	.	.	PROPN
admet-442	331	10	long	long	PROPN
admet-442	331	11	,	,	PUNCT
admet-442	331	12	y.	y.	PROPN
admet-442	331	13	iwai	iwai	PROPN
admet-442	331	14	,	,	PUNCT
admet-442	331	15	k.	k.	PROPN
admet-442	331	16	bourque	bourque	PROPN
admet-442	331	17	,	,	PUNCT
admet-442	331	18	t.	t.	PROPN
admet-442	331	19	chernova	chernova	PROPN
admet-442	331	20	,	,	PUNCT
admet-442	331	21	h.	h.	PROPN
admet-442	331	22	nishimura	nishimura	PROPN
admet-442	331	23	,	,	PUNCT
admet-442	331	24	l.j	l.j	PROPN
admet-442	331	25	.	.	PROPN
admet-442	331	26	fitz	fitz	PROPN
admet-442	331	27	,	,	PUNCT
admet-442	331	28	n.	n.	NOUN
admet-442	331	29	malenkovich	malenkovich	PROPN
admet-442	331	30	,	,	PUNCT
admet-442	331	31	t.	t.	PROPN
admet-442	331	32	okazaki	okazaki	PROPN
admet-442	331	33	,	,	PUNCT
admet-442	331	34	m.c	m.c	PROPN
admet-442	331	35	.	.	PROPN
admet-442	331	36	byrne	byrne	PROPN
admet-442	331	37	,	,	PUNCT
admet-442	331	38	h.f	h.f	PROPN
admet-442	331	39	.	.	PROPN
admet-442	331	40	horton	horton	PROPN
admet-442	331	41	,	,	PUNCT
admet-442	331	42	l.	l.	PROPN
admet-442	331	43	fouser	fouser	PROPN
admet-442	331	44	,	,	PUNCT
admet-442	331	45	l.	l.	PROPN
admet-442	331	46	carter	carter	PROPN
admet-442	331	47	,	,	PUNCT
admet-442	331	48	v.	v.	PROPN
admet-442	331	49	ling	ling	PROPN
admet-442	331	50	,	,	PUNCT
admet-442	331	51	m.r	m.r	PROPN
admet-442	331	52	.	.	PROPN
admet-442	331	53	bowman	bowman	PROPN
admet-442	331	54	,	,	PUNCT
admet-442	331	55	b.m	b.m	PROPN
admet-442	331	56	.	.	PROPN
admet-442	331	57	carreno	carreno	PROPN
admet-442	331	58	,	,	PUNCT
admet-442	331	59	m.	m.	NOUN
admet-442	331	60	collins	collins	PROPN
admet-442	331	61	,	,	PUNCT
admet-442	331	62	c.r	c.r	PROPN
admet-442	331	63	.	.	PROPN
admet-442	331	64	wood	wood	PROPN
admet-442	331	65	,	,	PUNCT
admet-442	331	66	t.	t.	NOUN
admet-442	331	67	honjo	honjo	PROPN
admet-442	331	68	.	.	PUNCT
admet-442	332	1	engagement	engagement	NOUN
admet-442	332	2	of	of	ADP
admet-442	332	3	the	the	DET
admet-442	332	4	pd-1	pd-1	ADJ
admet-442	332	5	immunoinhibitory	immunoinhibitory	ADJ
admet-442	332	6	receptor	receptor	NOUN
admet-442	332	7	by	by	ADP
admet-442	332	8	a	a	DET
admet-442	332	9	novel	novel	ADJ
admet-442	332	10	b7	b7	PROPN
admet-442	332	11	family	family	NOUN
admet-442	332	12	member	member	NOUN
admet-442	332	13	leads	lead	VERB
admet-442	332	14	to	to	ADP
admet-442	332	15	negative	negative	ADJ
admet-442	332	16	regulation	regulation	NOUN
admet-442	332	17	of	of	ADP
admet-442	332	18	lymphocyte	lymphocyte	ADJ
admet-442	332	19	activation	activation	NOUN
admet-442	332	20	,	,	PUNCT
admet-442	332	21	j	j	PROPN
admet-442	332	22	exp	exp	NOUN
admet-442	332	23	med	me	VERB
admet-442	332	24	192	192	NUM
admet-442	332	25	(	(	PUNCT
admet-442	332	26	2000	2000	NUM
admet-442	332	27	)	)	PUNCT
admet-442	332	28	10271034	10271034	NUM
admet-442	332	29	.	.	PUNCT
admet-442	333	1	[	[	X
admet-442	333	2	64	64	NUM
admet-442	333	3	]	]	X
admet-442	333	4	m.m	m.m	PROPN
admet-442	333	5	.	.	PROPN
admet-442	333	6	mazanet	mazanet	PROPN
admet-442	333	7	,	,	PUNCT
admet-442	333	8	c.c.w	c.c.w	NOUN
admet-442	333	9	.	.	PUNCT
admet-442	334	1	hughes	hughes	PROPN
admet-442	334	2	.	.	PUNCT
admet-442	335	1	b7	b7	PROPN
admet-442	335	2	-	-	PUNCT
admet-442	335	3	h1	h1	PROPN
admet-442	335	4	is	be	AUX
admet-442	335	5	expressed	express	VERB
admet-442	335	6	by	by	ADP
admet-442	335	7	human	human	ADJ
admet-442	335	8	endothelial	endothelial	ADJ
admet-442	335	9	cells	cell	NOUN
admet-442	335	10	and	and	CCONJ
admet-442	335	11	suppresses	suppress	VERB
admet-442	335	12	t	t	PROPN
admet-442	335	13	cell	cell	NOUN
admet-442	335	14	cytokine	cytokine	NOUN
admet-442	335	15	synthesis	synthesis	NOUN
admet-442	335	16	,	,	PUNCT
admet-442	335	17	journal	journal	NOUN
admet-442	335	18	of	of	ADP
admet-442	335	19	immunology	immunology	NOUN
admet-442	335	20	169	169	NUM
admet-442	335	21	(	(	PUNCT
admet-442	335	22	2002	2002	NUM
admet-442	335	23	)	)	PUNCT
admet-442	335	24	3581	3581	NUM
admet-442	335	25	-	-	SYM
admet-442	335	26	3588	3588	NUM
admet-442	335	27	.	.	PUNCT
admet-442	336	1	[	[	X
admet-442	336	2	65	65	NUM
admet-442	336	3	]	]	X
admet-442	336	4	m.	m.	NOUN
admet-442	336	5	collins	collins	PROPN
admet-442	336	6	,	,	PUNCT
admet-442	336	7	v.	v.	PROPN
admet-442	336	8	ling	ling	PROPN
admet-442	336	9	,	,	PUNCT
admet-442	336	10	b.m	b.m	PROPN
admet-442	336	11	.	.	PROPN
admet-442	336	12	carreno	carreno	PROPN
admet-442	336	13	.	.	PUNCT
admet-442	337	1	the	the	DET
admet-442	337	2	b7	b7	PROPN
admet-442	337	3	family	family	NOUN
admet-442	337	4	of	of	ADP
admet-442	337	5	immune	immune	NOUN
admet-442	337	6	-	-	PUNCT
admet-442	337	7	regulatory	regulatory	ADJ
admet-442	337	8	ligands	ligand	NOUN
admet-442	337	9	,	,	PUNCT
admet-442	337	10	genome	genome	NOUN
admet-442	337	11	biol	biol	NOUN
admet-442	337	12	6	6	NUM
admet-442	337	13	(	(	PUNCT
admet-442	337	14	2005	2005	NUM
admet-442	337	15	)	)	PUNCT
admet-442	337	16	223	223	NUM
admet-442	337	17	.	.	PUNCT
admet-442	338	1	[	[	X
admet-442	338	2	66	66	NUM
admet-442	338	3	]	]	X
admet-442	338	4	y.	y.	PROPN
admet-442	338	5	chen	chen	PROPN
admet-442	338	6	,	,	PUNCT
admet-442	338	7	p.	p.	PROPN
admet-442	338	8	liu	liu	PROPN
admet-442	338	9	,	,	PUNCT
admet-442	338	10	f.	f.	PROPN
admet-442	338	11	gao	gao	PROPN
admet-442	338	12	,	,	PUNCT
admet-442	338	13	h.	h.	PROPN
admet-442	338	14	cheng	cheng	PROPN
admet-442	338	15	,	,	PUNCT
admet-442	338	16	j.	j.	PROPN
admet-442	338	17	qi	qi	PROPN
admet-442	338	18	,	,	PUNCT
admet-442	338	19	g.f	g.f	PROPN
admet-442	338	20	.	.	PROPN
admet-442	338	21	gao	gao	PROPN
admet-442	338	22	.	.	PUNCT
admet-442	339	1	a	a	DET
admet-442	339	2	dimeric	dimeric	ADJ
admet-442	339	3	structure	structure	NOUN
admet-442	339	4	of	of	ADP
admet-442	339	5	pd	pd	PROPN
admet-442	339	6	-	-	PUNCT
admet-442	339	7	l1	l1	PROPN
admet-442	339	8	:	:	PUNCT
admet-442	339	9	functional	functional	ADJ
admet-442	339	10	units	unit	NOUN
admet-442	339	11	or	or	CCONJ
admet-442	339	12	evolutionary	evolutionary	ADJ
admet-442	339	13	relics	relic	NOUN
admet-442	339	14	?	?	PUNCT
admet-442	339	15	,	,	PUNCT
admet-442	339	16	protein	protein	NOUN
admet-442	339	17	cell	cell	NOUN
admet-442	339	18	1	1	NUM
admet-442	339	19	(	(	PUNCT
admet-442	339	20	2010	2010	NUM
admet-442	339	21	)	)	PUNCT
admet-442	339	22	153	153	NUM
admet-442	339	23	-	-	SYM
admet-442	339	24	160	160	NUM
admet-442	339	25	.	.	PUNCT
admet-442	340	1	[	[	X
admet-442	340	2	67	67	NUM
admet-442	340	3	]	]	X
admet-442	340	4	m.j	m.j	PROPN
admet-442	340	5	.	.	PROPN
admet-442	340	6	butte	butte	PROPN
admet-442	340	7	,	,	PUNCT
admet-442	340	8	m.e	m.e	PROPN
admet-442	340	9	.	.	PROPN
admet-442	340	10	keir	keir	PROPN
admet-442	340	11	,	,	PUNCT
admet-442	340	12	t.b	t.b	PROPN
admet-442	340	13	.	.	PROPN
admet-442	340	14	phamduy	phamduy	PROPN
admet-442	340	15	,	,	PUNCT
admet-442	340	16	a.h	a.h	PROPN
admet-442	340	17	.	.	PROPN
admet-442	340	18	sharpe	sharpe	PROPN
admet-442	340	19	,	,	PUNCT
admet-442	340	20	g.j	g.j	PROPN
admet-442	340	21	.	.	PROPN
admet-442	340	22	freeman	freeman	PROPN
admet-442	340	23	.	.	PROPN
admet-442	340	24	programmed	program	VERB
admet-442	340	25	death-1	death-1	NUM
admet-442	340	26	ligand	ligand	NOUN
admet-442	340	27	1	1	NUM
admet-442	340	28	interacts	interact	VERB
admet-442	340	29	specifically	specifically	ADV
admet-442	340	30	with	with	ADP
admet-442	340	31	the	the	DET
admet-442	340	32	b7	b7	PROPN
admet-442	340	33	-	-	PUNCT
admet-442	340	34	1	1	NUM
admet-442	340	35	costimulatory	costimulatory	NOUN
admet-442	340	36	molecule	molecule	NOUN
admet-442	340	37	to	to	PART
admet-442	340	38	inhibit	inhibit	VERB
admet-442	340	39	t	t	NOUN
admet-442	340	40	cell	cell	NOUN
admet-442	340	41	responses	response	NOUN
admet-442	340	42	,	,	PUNCT
admet-442	340	43	immunity	immunity	NOUN
admet-442	340	44	27	27	NUM
admet-442	340	45	(	(	PUNCT
admet-442	340	46	2007	2007	NUM
admet-442	340	47	)	)	PUNCT
admet-442	340	48	111	111	NUM
admet-442	340	49	-	-	SYM
admet-442	340	50	122	122	NUM
admet-442	340	51	.	.	PUNCT
admet-442	341	1	[	[	X
admet-442	341	2	68	68	NUM
admet-442	341	3	]	]	X
admet-442	341	4	s.j	s.j	PROPN
admet-442	341	5	.	.	PROPN
admet-442	341	6	lee	lee	PROPN
admet-442	341	7	,	,	PUNCT
admet-442	341	8	b.c	b.c	PROPN
admet-442	341	9	.	.	PROPN
admet-442	341	10	jang	jang	PROPN
admet-442	341	11	,	,	PUNCT
admet-442	341	12	s.w	s.w	PROPN
admet-442	341	13	.	.	PROPN
admet-442	341	14	lee	lee	PROPN
admet-442	341	15	,	,	PUNCT
admet-442	341	16	y.i	y.i	PROPN
admet-442	341	17	.	.	PROPN
admet-442	341	18	yang	yang	PROPN
admet-442	341	19	,	,	PUNCT
admet-442	341	20	s.i	s.i	PROPN
admet-442	341	21	.	.	PROPN
admet-442	341	22	suh	suh	PROPN
admet-442	341	23	,	,	PUNCT
admet-442	341	24	y.m	y.m	PROPN
admet-442	341	25	.	.	PROPN
admet-442	341	26	park	park	PROPN
admet-442	341	27	,	,	PUNCT
admet-442	341	28	s.	s.	PROPN
admet-442	342	1	oh	oh	INTJ
admet-442	342	2	,	,	PUNCT
admet-442	342	3	j.g	j.g	PROPN
admet-442	342	4	.	.	PROPN
admet-442	342	5	shin	shin	PROPN
admet-442	342	6	,	,	PUNCT
admet-442	342	7	s.	s.	PROPN
admet-442	342	8	yao	yao	PROPN
admet-442	342	9	,	,	PUNCT
admet-442	342	10	l.p	l.p	PROPN
admet-442	343	1	.	.	PROPN
admet-442	343	2	chen	chen	PROPN
admet-442	343	3	,	,	PUNCT
admet-442	343	4	i.h	i.h	PROPN
admet-442	343	5	.	.	PROPN
admet-442	343	6	choi	choi	PROPN
admet-442	343	7	.	.	PUNCT
admet-442	344	1	interferon	interferon	ADJ
admet-442	344	2	regulatory	regulatory	NOUN
admet-442	344	3	factor-1	factor-1	PROPN
admet-442	344	4	is	be	AUX
admet-442	344	5	prerequisite	prerequisite	NOUN
admet-442	344	6	to	to	ADP
admet-442	344	7	the	the	DET
admet-442	344	8	constitutive	constitutive	ADJ
admet-442	344	9	expression	expression	NOUN
admet-442	344	10	and	and	CCONJ
admet-442	344	11	ifn	ifn	NOUN
admet-442	344	12	-	-	PUNCT
admet-442	344	13	gammainduced	gammainduce	VERB
admet-442	344	14	upregulation	upregulation	NOUN
admet-442	344	15	of	of	ADP
admet-442	344	16	b7	b7	PROPN
admet-442	344	17	-	-	PUNCT
admet-442	344	18	h1	h1	PROPN
admet-442	344	19	(	(	PUNCT
admet-442	344	20	cd274	cd274	PROPN
admet-442	344	21	)	)	PUNCT
admet-442	344	22	,	,	PUNCT
admet-442	344	23	febs	febs	NOUN
admet-442	344	24	lett	lett	PROPN
admet-442	344	25	580	580	NUM
admet-442	344	26	(	(	PUNCT
admet-442	344	27	2006	2006	NUM
admet-442	344	28	)	)	PUNCT
admet-442	344	29	755	755	NUM
admet-442	344	30	-	-	SYM
admet-442	344	31	762	762	NUM
admet-442	344	32	.	.	PUNCT
admet-442	345	1	[	[	X
admet-442	345	2	69	69	NUM
admet-442	345	3	]	]	X
admet-442	345	4	s.j	s.j	PROPN
admet-442	345	5	.	.	PROPN
admet-442	345	6	wolfle	wolfle	PROPN
admet-442	345	7	,	,	PUNCT
admet-442	345	8	j.	j.	PROPN
admet-442	345	9	strebovsky	strebovsky	PROPN
admet-442	345	10	,	,	PUNCT
admet-442	345	11	h.	h.	PROPN
admet-442	345	12	bartz	bartz	PROPN
admet-442	345	13	,	,	PUNCT
admet-442	345	14	a.	a.	PROPN
admet-442	345	15	sahr	sahr	PROPN
admet-442	345	16	,	,	PUNCT
admet-442	345	17	c.	c.	PROPN
admet-442	345	18	arnold	arnold	PROPN
admet-442	345	19	,	,	PUNCT
admet-442	345	20	c.	c.	PROPN
admet-442	345	21	kaiser	kaiser	PROPN
admet-442	345	22	,	,	PUNCT
admet-442	345	23	a.h	a.h	PROPN
admet-442	345	24	.	.	PROPN
admet-442	345	25	dalpke	dalpke	PROPN
admet-442	345	26	,	,	PUNCT
admet-442	345	27	k.	k.	PROPN
admet-442	345	28	heeg	heeg	PROPN
admet-442	345	29	.	.	PUNCT
admet-442	346	1	pd	pd	PROPN
admet-442	346	2	-	-	PUNCT
admet-442	346	3	l1	l1	PROPN
admet-442	346	4	expression	expression	NOUN
admet-442	346	5	on	on	ADP
admet-442	346	6	tolerogenic	tolerogenic	ADJ
admet-442	346	7	apcs	apc	NOUN
admet-442	346	8	is	be	AUX
admet-442	346	9	controlled	control	VERB
admet-442	346	10	by	by	ADP
admet-442	346	11	stat-3	stat-3	PROPN
admet-442	346	12	,	,	PUNCT
admet-442	346	13	european	european	ADJ
admet-442	346	14	journal	journal	NOUN
admet-442	346	15	of	of	ADP
admet-442	346	16	immunology	immunology	NOUN
admet-442	346	17	41	41	NUM
admet-442	346	18	(	(	PUNCT
admet-442	346	19	2011	2011	NUM
admet-442	346	20	)	)	PUNCT
admet-442	346	21	413	413	NUM
admet-442	346	22	-	-	SYM
admet-442	346	23	424	424	NUM
admet-442	346	24	.	.	PUNCT
admet-442	347	1	[	[	X
admet-442	347	2	70	70	NUM
admet-442	347	3	]	]	X
admet-442	347	4	m.j	m.j	PROPN
admet-442	347	5	.	.	PROPN
admet-442	347	6	eppihimer	eppihimer	PROPN
admet-442	347	7	,	,	PUNCT
admet-442	347	8	j.	j.	PROPN
admet-442	347	9	gunn	gunn	PROPN
admet-442	347	10	,	,	PUNCT
admet-442	347	11	g.j	g.j	PROPN
admet-442	347	12	.	.	PROPN
admet-442	347	13	freeman	freeman	PROPN
admet-442	347	14	,	,	PUNCT
admet-442	347	15	e.a	e.a	PROPN
admet-442	347	16	.	.	PROPN
admet-442	347	17	greenfield	greenfield	NOUN
admet-442	347	18	,	,	PUNCT
admet-442	347	19	t.	t.	PROPN
admet-442	347	20	chernova	chernova	PROPN
admet-442	347	21	,	,	PUNCT
admet-442	347	22	j.	j.	PROPN
admet-442	347	23	erickson	erickson	PROPN
admet-442	347	24	,	,	PUNCT
admet-442	347	25	j.p	j.p	PROPN
admet-442	347	26	.	.	PROPN
admet-442	347	27	leonard	leonard	PROPN
admet-442	347	28	.	.	PUNCT
admet-442	348	1	expression	expression	NOUN
admet-442	348	2	and	and	CCONJ
admet-442	348	3	regulation	regulation	NOUN
admet-442	348	4	of	of	ADP
admet-442	348	5	the	the	DET
admet-442	348	6	pd	pd	PROPN
admet-442	348	7	-	-	PROPN
admet-442	348	8	l1	l1	PROPN
admet-442	348	9	immunoinhibitory	immunoinhibitory	ADJ
admet-442	348	10	molecule	molecule	NOUN
admet-442	348	11	on	on	ADP
admet-442	348	12	microvascular	microvascular	ADJ
admet-442	348	13	endothelial	endothelial	ADJ
admet-442	348	14	cells	cell	NOUN
admet-442	348	15	,	,	PUNCT
admet-442	348	16	microcirculation	microcirculation	NOUN
admet-442	348	17	9	9	NUM
admet-442	348	18	(	(	PUNCT
admet-442	348	19	2002	2002	NUM
admet-442	348	20	)	)	PUNCT
admet-442	348	21	133	133	NUM
admet-442	348	22	-	-	SYM
admet-442	348	23	145	145	NUM
admet-442	348	24	.	.	PUNCT
admet-442	349	1	[	[	X
admet-442	349	2	71	71	NUM
admet-442	349	3	]	]	X
admet-442	349	4	b.	b.	PROPN
admet-442	349	5	schreiner	schreiner	PROPN
admet-442	349	6	,	,	PUNCT
admet-442	349	7	m.	m.	NOUN
admet-442	349	8	mitsdoerffer	mitsdoerffer	NOUN
admet-442	349	9	,	,	PUNCT
admet-442	349	10	b.c	b.c	PROPN
admet-442	349	11	.	.	PROPN
admet-442	349	12	kieseier	kieseier	PROPN
admet-442	349	13	,	,	PUNCT
admet-442	349	14	l.	l.	PROPN
admet-442	349	15	chen	chen	PROPN
admet-442	349	16	,	,	PUNCT
admet-442	349	17	h.p	h.p	PROPN
admet-442	349	18	.	.	PROPN
admet-442	349	19	hartung	hartung	PROPN
admet-442	349	20	,	,	PUNCT
admet-442	349	21	m.	m.	NOUN
admet-442	349	22	weller	weller	PROPN
admet-442	349	23	,	,	PUNCT
admet-442	349	24	h.	h.	PROPN
admet-442	349	25	wiendl	wiendl	PROPN
admet-442	349	26	.	.	PUNCT
admet-442	350	1	interferonbeta	interferonbeta	NOUN
admet-442	350	2	enhances	enhance	VERB
admet-442	350	3	monocyte	monocyte	NOUN
admet-442	350	4	and	and	CCONJ
admet-442	350	5	dendritic	dendritic	ADJ
admet-442	350	6	cell	cell	NOUN
admet-442	350	7	expression	expression	NOUN
admet-442	350	8	of	of	ADP
admet-442	350	9	b7	b7	PROPN
admet-442	350	10	-	-	PUNCT
admet-442	350	11	h1	h1	PROPN
admet-442	350	12	(	(	PUNCT
admet-442	350	13	pd	pd	NOUN
admet-442	350	14	-	-	PUNCT
admet-442	350	15	l1	l1	PROPN
admet-442	350	16	)	)	PUNCT
admet-442	350	17	,	,	PUNCT
admet-442	350	18	a	a	DET
admet-442	350	19	strong	strong	ADJ
admet-442	350	20	inhibitor	inhibitor	NOUN
admet-442	350	21	of	of	ADP
admet-442	350	22	autologous	autologous	ADJ
admet-442	350	23	t	t	NOUN
admet-442	350	24	-	-	PUNCT
admet-442	350	25	cell	cell	NOUN
admet-442	350	26	activation	activation	NOUN
admet-442	350	27	:	:	PUNCT
admet-442	350	28	relevance	relevance	NOUN
admet-442	350	29	for	for	ADP
admet-442	350	30	the	the	DET
admet-442	350	31	immune	immune	ADJ
admet-442	350	32	modulatory	modulatory	ADJ
admet-442	350	33	effect	effect	NOUN
admet-442	350	34	in	in	ADP
admet-442	350	35	multiple	multiple	ADJ
admet-442	350	36	sclerosis	sclerosis	NOUN
admet-442	350	37	,	,	PUNCT
admet-442	350	38	j	j	PROPN
admet-442	350	39	neuroimmunol	neuroimmunol	PROPN
admet-442	350	40	155	155	NUM
admet-442	350	41	(	(	PUNCT
admet-442	350	42	2004	2004	NUM
admet-442	350	43	)	)	PUNCT
admet-442	350	44	172	172	NUM
admet-442	350	45	-	-	SYM
admet-442	350	46	182	182	NUM
admet-442	350	47	.	.	PUNCT
admet-442	351	1	[	[	X
admet-442	351	2	72	72	NUM
admet-442	351	3	]	]	PUNCT
admet-442	351	4	p.	p.	NOUN
admet-442	351	5	loke	loke	PROPN
admet-442	351	6	,	,	PUNCT
admet-442	351	7	j.p	j.p	PROPN
admet-442	351	8	.	.	PROPN
admet-442	351	9	allison	allison	PROPN
admet-442	351	10	.	.	PUNCT
admet-442	352	1	pd	pd	PROPN
admet-442	352	2	-	-	PROPN
admet-442	352	3	l1	l1	PROPN
admet-442	352	4	and	and	CCONJ
admet-442	352	5	pd	pd	PROPN
admet-442	352	6	-	-	PUNCT
admet-442	352	7	l2	l2	NOUN
admet-442	352	8	are	be	AUX
admet-442	352	9	differentially	differentially	ADV
admet-442	352	10	regulated	regulate	VERB
admet-442	352	11	by	by	ADP
admet-442	352	12	th1	th1	PROPN
admet-442	352	13	and	and	CCONJ
admet-442	352	14	th2	th2	PROPN
admet-442	352	15	cells	cell	NOUN
admet-442	352	16	,	,	PUNCT
admet-442	352	17	proc	proc	PROPN
admet-442	352	18	natl	natl	PROPN
admet-442	352	19	acad	acad	PROPN
admet-442	352	20	sci	sci	PROPN
admet-442	352	21	u	u	PROPN
admet-442	352	22	s	s	PROPN
admet-442	352	23	a	a	DET
admet-442	352	24	100	100	NUM
admet-442	352	25	(	(	PUNCT
admet-442	352	26	2003	2003	NUM
admet-442	352	27	)	)	PUNCT
admet-442	352	28	5336	5336	NUM
admet-442	352	29	-	-	SYM
admet-442	352	30	5341	5341	NUM
admet-442	352	31	.	.	PUNCT
admet-442	353	1	[	[	X
admet-442	353	2	73	73	NUM
admet-442	353	3	]	]	X
admet-442	353	4	j.a	j.a	PROPN
admet-442	353	5	.	.	PROPN
admet-442	353	6	brown	brown	PROPN
admet-442	353	7	,	,	PUNCT
admet-442	353	8	d.m	d.m	PROPN
admet-442	353	9	.	.	PUNCT
admet-442	354	1	dorfman	dorfman	PROPN
admet-442	354	2	,	,	PUNCT
admet-442	354	3	f.r	f.r	PROPN
admet-442	354	4	.	.	PROPN
admet-442	354	5	ma	ma	PROPN
admet-442	354	6	,	,	PUNCT
admet-442	354	7	e.l	e.l	PROPN
admet-442	354	8	.	.	PROPN
admet-442	354	9	sullivan	sullivan	PROPN
admet-442	354	10	,	,	PUNCT
admet-442	354	11	o.	o.	PROPN
admet-442	354	12	munoz	munoz	PROPN
admet-442	354	13	,	,	PUNCT
admet-442	354	14	c.r	c.r	PROPN
admet-442	354	15	.	.	PROPN
admet-442	354	16	wood	wood	PROPN
admet-442	354	17	,	,	PUNCT
admet-442	354	18	e.a	e.a	PROPN
admet-442	354	19	.	.	PROPN
admet-442	354	20	greenfield	greenfield	PROPN
admet-442	354	21	,	,	PUNCT
admet-442	354	22	g.j	g.j	PROPN
admet-442	354	23	.	.	PROPN
admet-442	354	24	freeman	freeman	PROPN
admet-442	354	25	.	.	PUNCT
admet-442	355	1	blockade	blockade	NOUN
admet-442	355	2	of	of	ADP
admet-442	355	3	programmed	program	VERB
admet-442	355	4	death-1	death-1	NUM
admet-442	355	5	ligands	ligand	NOUN
admet-442	355	6	on	on	ADP
admet-442	355	7	dendritic	dendritic	ADJ
admet-442	355	8	cells	cell	NOUN
admet-442	355	9	enhances	enhance	VERB
admet-442	355	10	t	t	NOUN
admet-442	355	11	cell	cell	NOUN
admet-442	355	12	activation	activation	NOUN
admet-442	355	13	and	and	CCONJ
admet-442	355	14	cytokine	cytokine	NOUN
admet-442	355	15	production	production	NOUN
admet-442	355	16	,	,	PUNCT
admet-442	355	17	j	j	PROPN
admet-442	355	18	immunol	immunol	NOUN
admet-442	355	19	170	170	NUM
admet-442	355	20	(	(	PUNCT
admet-442	355	21	2003	2003	NUM
admet-442	355	22	)	)	PUNCT
admet-442	355	23	1257	1257	NUM
admet-442	355	24	-	-	SYM
admet-442	355	25	1266	1266	NUM
admet-442	355	26	.	.	PUNCT
admet-442	356	1	[	[	X
admet-442	356	2	74	74	NUM
admet-442	356	3	]	]	X
admet-442	356	4	j.n	j.n	PROPN
admet-442	356	5	.	.	PROPN
admet-442	356	6	ou	ou	PROPN
admet-442	356	7	,	,	PUNCT
admet-442	356	8	a.e	a.e	PROPN
admet-442	356	9	.	.	PROPN
admet-442	356	10	wiedeman	wiedeman	PROPN
admet-442	356	11	,	,	PUNCT
admet-442	356	12	a.m.	a.m.	PROPN
admet-442	356	13	stevens	stevens	PROPN
admet-442	356	14	.	.	PUNCT
admet-442	356	15	tnf	tnf	PROPN
admet-442	356	16	-	-	PUNCT
admet-442	356	17	alpha	alpha	PROPN
admet-442	356	18	and	and	CCONJ
admet-442	356	19	tgf	tgf	PROPN
admet-442	356	20	-	-	PUNCT
admet-442	356	21	beta	beta	NOUN
admet-442	356	22	counter	counter	NOUN
admet-442	356	23	-	-	NOUN
admet-442	356	24	regulate	regulate	ADJ
admet-442	356	25	pd	pd	ADJ
admet-442	356	26	-	-	PUNCT
admet-442	356	27	l1	l1	PROPN
admet-442	356	28	expression	expression	NOUN
admet-442	356	29	on	on	ADP
admet-442	356	30	monocytes	monocyte	NOUN
admet-442	356	31	in	in	ADP
admet-442	356	32	systemic	systemic	ADJ
admet-442	356	33	lupus	lupus	PROPN
admet-442	356	34	erythematosus	erythematosus	PROPN
admet-442	356	35	,	,	PUNCT
admet-442	356	36	sci	sci	PROPN
admet-442	356	37	rep	rep	PROPN
admet-442	356	38	2	2	NUM
admet-442	356	39	(	(	PUNCT
admet-442	356	40	2012	2012	NUM
admet-442	356	41	)	)	PUNCT
admet-442	356	42	295	295	NUM
admet-442	356	43	.	.	PUNCT
admet-442	357	1	[	[	X
admet-442	357	2	75	75	NUM
admet-442	357	3	]	]	X
admet-442	357	4	m.r	m.r	PROPN
admet-442	357	5	.	.	PROPN
admet-442	357	6	green	green	PROPN
admet-442	357	7	,	,	PUNCT
admet-442	357	8	s.	s.	PROPN
admet-442	357	9	rodig	rodig	PROPN
admet-442	357	10	,	,	PUNCT
admet-442	357	11	p.	p.	NOUN
admet-442	357	12	juszczynski	juszczynski	NOUN
admet-442	357	13	,	,	PUNCT
admet-442	357	14	j.	j.	PROPN
admet-442	357	15	ouyang	ouyang	PROPN
admet-442	357	16	,	,	PUNCT
admet-442	357	17	p.	p.	PROPN
admet-442	357	18	sinha	sinha	PROPN
admet-442	357	19	,	,	PUNCT
admet-442	357	20	e.	e.	PROPN
admet-442	357	21	o'donnel	o'donnel	PROPN
admet-442	357	22	.	.	PUNCT
admet-442	358	1	constitutive	constitutive	ADJ
admet-442	358	2	ap-1	ap-1	NOUN
admet-442	358	3	activity	activity	NOUN
admet-442	358	4	and	and	CCONJ
admet-442	358	5	ebv	ebv	NOUN
admet-442	358	6	infection	infection	NOUN
admet-442	358	7	induce	induce	VERB
admet-442	358	8	pd	pd	NOUN
admet-442	358	9	-	-	PROPN
admet-442	358	10	l1	l1	PROPN
admet-442	358	11	in	in	ADP
admet-442	358	12	hodgkin	hodgkin	PROPN
admet-442	358	13	lymphomas	lymphoma	NOUN
admet-442	358	14	and	and	CCONJ
admet-442	358	15	posttransplant	posttransplant	ADJ
admet-442	358	16	lymphoproliferative	lymphoproliferative	ADJ
admet-442	358	17	disorders	disorder	NOUN
admet-442	358	18	:	:	PUNCT
admet-442	358	19	implications	implication	NOUN
admet-442	358	20	for	for	ADP
admet-442	358	21	targeted	target	VERB
admet-442	358	22	therapy	therapy	NOUN
admet-442	358	23	(	(	PUNCT
admet-442	358	24	vol	vol	NOUN
admet-442	358	25	18	18	NUM
admet-442	358	26	,	,	PUNCT
admet-442	358	27	pg	pg	NOUN
admet-442	358	28	1611	1611	NUM
admet-442	358	29	,	,	PUNCT
admet-442	358	30	2012	2012	NUM
admet-442	358	31	)	)	PUNCT
admet-442	358	32	,	,	PUNCT
admet-442	358	33	clin	clin	PROPN
admet-442	358	34	cancer	cancer	NOUN
admet-442	358	35	res	re	VERB
admet-442	358	36	18	18	NUM
admet-442	358	37	(	(	PUNCT
admet-442	358	38	2012	2012	NUM
admet-442	358	39	)	)	PUNCT
admet-442	358	40	2117	2117	NUM
admet-442	358	41	-	-	SYM
admet-442	358	42	2117	2117	NUM
admet-442	358	43	.	.	PUNCT
admet-442	359	1	[	[	X
admet-442	359	2	76	76	X
admet-442	359	3	]	]	PUNCT
admet-442	359	4	t.	t.	PROPN
admet-442	359	5	kim	kim	PROPN
admet-442	359	6	,	,	PUNCT
admet-442	359	7	a.	a.	NOUN
admet-442	359	8	veronese	veronese	PROPN
admet-442	359	9	,	,	PUNCT
admet-442	359	10	f.	f.	PROPN
admet-442	359	11	pichiorri	pichiorri	PROPN
admet-442	359	12	,	,	PUNCT
admet-442	359	13	t.j	t.j	PROPN
admet-442	359	14	.	.	PROPN
admet-442	359	15	lee	lee	PROPN
admet-442	359	16	,	,	PUNCT
admet-442	359	17	y.j	y.j	PROPN
admet-442	359	18	.	.	PROPN
admet-442	359	19	jeon	jeon	PROPN
admet-442	359	20	,	,	PUNCT
admet-442	359	21	s.	s.	PROPN
admet-442	359	22	volinia	volinia	PROPN
admet-442	359	23	,	,	PUNCT
admet-442	359	24	p.	p.	PROPN
admet-442	359	25	pineau	pineau	PROPN
admet-442	359	26	,	,	PUNCT
admet-442	359	27	a.	a.	PROPN
admet-442	359	28	marchio	marchio	PROPN
admet-442	359	29	,	,	PUNCT
admet-442	359	30	j.	j.	PROPN
admet-442	359	31	palatini	palatini	PROPN
admet-442	359	32	,	,	PUNCT
admet-442	359	33	s.s	s.s	PROPN
admet-442	359	34	.	.	PROPN
admet-442	359	35	suh	suh	PROPN
admet-442	359	36	,	,	PUNCT
admet-442	359	37	h.	h.	PROPN
admet-442	359	38	alder	alder	PROPN
admet-442	359	39	,	,	PUNCT
admet-442	359	40	c.g	c.g	PROPN
admet-442	359	41	.	.	PROPN
admet-442	359	42	liu	liu	PROPN
admet-442	359	43	,	,	PUNCT
admet-442	359	44	a.	a.	PROPN
admet-442	359	45	dejean	dejean	PROPN
admet-442	359	46	,	,	PUNCT
admet-442	359	47	c.m	c.m	PROPN
admet-442	359	48	.	.	PUNCT
admet-442	359	49	croce	croce	PROPN
admet-442	359	50	.	.	PUNCT
admet-442	359	51	p53	p53	NOUN
admet-442	359	52	regulates	regulate	VERB
admet-442	359	53	epithelial	epithelial	ADJ
admet-442	359	54	-	-	PUNCT
admet-442	359	55	mesenchymal	mesenchymal	NOUN
admet-442	359	56	transition	transition	NOUN
admet-442	359	57	through	through	ADP
admet-442	359	58	micrornas	microrna	NOUN
admet-442	359	59	targeting	target	VERB
admet-442	359	60	zeb1	zeb1	PROPN
admet-442	359	61	and	and	CCONJ
admet-442	359	62	zeb2	zeb2	PROPN
admet-442	359	63	,	,	PUNCT
admet-442	359	64	journal	journal	NOUN
admet-442	359	65	of	of	ADP
admet-442	359	66	experimental	experimental	ADJ
admet-442	359	67	medicine	medicine	NOUN
admet-442	359	68	208	208	NUM
admet-442	359	69	(	(	PUNCT
admet-442	359	70	2011	2011	NUM
admet-442	359	71	)	)	PUNCT
admet-442	359	72	875883	875883	NUM
admet-442	359	73	.	.	PUNCT
admet-442	360	1	admet	admet	PROPN
admet-442	360	2	&	&	CCONJ
admet-442	360	3	dmpk	dmpk	PROPN
admet-442	360	4	5(3	5(3	NUM
admet-442	360	5	)	)	PUNCT
admet-442	360	6	(	(	PUNCT
admet-442	360	7	2017	2017	NUM
admet-442	360	8	)	)	PUNCT
admet-442	360	9	159	159	NUM
admet-442	360	10	-	-	SYM
admet-442	360	11	172	172	NUM
admet-442	360	12	the	the	DET
admet-442	360	13	function	function	NOUN
admet-442	360	14	and	and	CCONJ
admet-442	360	15	regulation	regulation	NOUN
admet-442	360	16	of	of	ADP
admet-442	360	17	pd	pd	PROPN
admet-442	360	18	-	-	PROPN
admet-442	360	19	l1	l1	PROPN
admet-442	360	20	in	in	ADP
admet-442	360	21	immunotherapy	immunotherapy	NOUN
admet-442	360	22	doi	doi	NOUN
admet-442	360	23	:	:	PUNCT
admet-442	360	24	10.5599	10.5599	NUM
admet-442	360	25	/	/	SYM
admet-442	360	26	admet.5.3.442	admet.5.3.442	NUM
admet-442	360	27	171	171	NUM
admet-442	361	1	[	[	X
admet-442	361	2	77	77	NUM
admet-442	361	3	]	]	PUNCT
admet-442	361	4	x.	x.	PROPN
admet-442	361	5	wang	wang	PROPN
admet-442	361	6	,	,	PUNCT
admet-442	361	7	j.g	j.g	PROPN
admet-442	361	8	.	.	PROPN
admet-442	361	9	li	li	PROPN
admet-442	361	10	,	,	PUNCT
admet-442	361	11	k.	k.	PROPN
admet-442	361	12	dong	dong	PROPN
admet-442	361	13	,	,	PUNCT
admet-442	361	14	f.	f.	PROPN
admet-442	361	15	lin	lin	PROPN
admet-442	361	16	,	,	PUNCT
admet-442	361	17	m.	m.	NOUN
admet-442	361	18	long	long	PROPN
admet-442	361	19	,	,	PUNCT
admet-442	361	20	y.r	y.r	PROPN
admet-442	361	21	.	.	PROPN
admet-442	361	22	ouyang	ouyang	PROPN
admet-442	361	23	,	,	PUNCT
admet-442	361	24	j.x	j.x	PROPN
admet-442	361	25	.	.	PROPN
admet-442	361	26	wei	wei	PROPN
admet-442	361	27	,	,	PUNCT
admet-442	361	28	x.	x.	PROPN
admet-442	361	29	chen	chen	PROPN
admet-442	361	30	,	,	PUNCT
admet-442	361	31	y.y	y.y	PROPN
admet-442	361	32	.	.	PROPN
admet-442	361	33	weng	weng	PROPN
admet-442	361	34	,	,	PUNCT
admet-442	361	35	t.	t.	PROPN
admet-442	361	36	he	he	PRON
admet-442	361	37	,	,	PUNCT
admet-442	361	38	h.z	h.z	PROPN
admet-442	361	39	.	.	PROPN
admet-442	361	40	zhang	zhang	PROPN
admet-442	361	41	.	.	PUNCT
admet-442	362	1	tumor	tumor	PROPN
admet-442	362	2	suppressor	suppressor	NOUN
admet-442	362	3	mir-34a	mir-34a	NUM
admet-442	362	4	targets	target	VERB
admet-442	362	5	pd	pd	PROPN
admet-442	362	6	-	-	PUNCT
admet-442	362	7	l1	l1	PROPN
admet-442	362	8	and	and	CCONJ
admet-442	362	9	functions	function	NOUN
admet-442	362	10	as	as	ADP
admet-442	362	11	a	a	DET
admet-442	362	12	potential	potential	ADJ
admet-442	362	13	immunotherapeutic	immunotherapeutic	ADJ
admet-442	362	14	target	target	NOUN
admet-442	362	15	in	in	ADP
admet-442	362	16	acute	acute	ADJ
admet-442	362	17	myeloid	myeloid	ADJ
admet-442	362	18	leukemia	leukemia	NOUN
admet-442	362	19	,	,	PUNCT
admet-442	362	20	cell	cell	NOUN
admet-442	362	21	signal	signal	NOUN
admet-442	362	22	27	27	NUM
admet-442	362	23	(	(	PUNCT
admet-442	362	24	2015	2015	NUM
admet-442	362	25	)	)	PUNCT
admet-442	362	26	443	443	NUM
admet-442	362	27	-	-	SYM
admet-442	362	28	452	452	NUM
admet-442	362	29	.	.	PUNCT
admet-442	363	1	[	[	X
admet-442	363	2	78	78	NUM
admet-442	363	3	]	]	PUNCT
admet-442	363	4	k.	k.	PROPN
admet-442	363	5	hirahara	hirahara	PROPN
admet-442	363	6	,	,	PUNCT
admet-442	363	7	k.	k.	PROPN
admet-442	363	8	ghoreschi	ghoreschi	PROPN
admet-442	363	9	,	,	PUNCT
admet-442	363	10	x.p	x.p	PROPN
admet-442	363	11	.	.	PROPN
admet-442	363	12	yang	yang	PROPN
admet-442	363	13	,	,	PUNCT
admet-442	363	14	h.	h.	PROPN
admet-442	363	15	takahashi	takahashi	PROPN
admet-442	363	16	,	,	PUNCT
admet-442	363	17	a.	a.	PROPN
admet-442	363	18	laurence	laurence	PROPN
admet-442	363	19	,	,	PUNCT
admet-442	363	20	g.	g.	PROPN
admet-442	363	21	vahedi	vahedi	PROPN
admet-442	363	22	,	,	PUNCT
admet-442	363	23	g.	g.	PROPN
admet-442	363	24	sciume	sciume	PROPN
admet-442	363	25	,	,	PUNCT
admet-442	363	26	a.o	a.o	PROPN
admet-442	363	27	.	.	PROPN
admet-442	363	28	hall	hall	PROPN
admet-442	363	29	,	,	PUNCT
admet-442	363	30	c.d	c.d	PROPN
admet-442	363	31	.	.	PROPN
admet-442	363	32	dupont	dupont	PROPN
admet-442	363	33	,	,	PUNCT
admet-442	363	34	l.m	l.m	PROPN
admet-442	363	35	.	.	PROPN
admet-442	363	36	francisco	francisco	PROPN
admet-442	363	37	,	,	PUNCT
admet-442	363	38	q.	q.	PROPN
admet-442	363	39	chen	chen	PROPN
admet-442	363	40	,	,	PUNCT
admet-442	363	41	m.	m.	PROPN
admet-442	363	42	tanaka	tanaka	PROPN
admet-442	363	43	,	,	PUNCT
admet-442	363	44	y.	y.	PROPN
admet-442	363	45	kanno	kanno	PROPN
admet-442	363	46	,	,	PUNCT
admet-442	363	47	h.w	h.w	PROPN
admet-442	363	48	.	.	PROPN
admet-442	363	49	sun	sun	PROPN
admet-442	363	50	,	,	PUNCT
admet-442	363	51	a.h	a.h	PROPN
admet-442	363	52	.	.	PROPN
admet-442	363	53	sharpe	sharpe	PROPN
admet-442	363	54	,	,	PUNCT
admet-442	363	55	c.a	c.a	PROPN
admet-442	363	56	.	.	PROPN
admet-442	363	57	hunter	hunter	PROPN
admet-442	363	58	,	,	PUNCT
admet-442	363	59	j.j	j.j	PROPN
admet-442	363	60	.	.	PROPN
admet-442	363	61	o'shea	o'shea	PROPN
admet-442	363	62	.	.	PUNCT
admet-442	364	1	interleukin-27	interleukin-27	ADJ
admet-442	364	2	priming	priming	NOUN
admet-442	364	3	of	of	ADP
admet-442	364	4	t	t	PROPN
admet-442	364	5	cells	cell	NOUN
admet-442	364	6	controls	control	NOUN
admet-442	364	7	il-17	il-17	PART
admet-442	364	8	production	production	NOUN
admet-442	364	9	in	in	ADP
admet-442	364	10	trans	tran	NOUN
admet-442	364	11	via	via	ADP
admet-442	364	12	induction	induction	NOUN
admet-442	364	13	of	of	ADP
admet-442	364	14	the	the	DET
admet-442	364	15	ligand	ligand	ADJ
admet-442	364	16	pd	pd	PROPN
admet-442	364	17	-	-	PUNCT
admet-442	364	18	l1	l1	PROPN
admet-442	364	19	,	,	PUNCT
admet-442	364	20	immunity	immunity	NOUN
admet-442	364	21	36	36	NUM
admet-442	364	22	(	(	PUNCT
admet-442	364	23	2012	2012	NUM
admet-442	364	24	)	)	PUNCT
admet-442	364	25	1017	1017	NUM
admet-442	364	26	-	-	SYM
admet-442	364	27	1030	1030	NUM
admet-442	364	28	.	.	PUNCT
admet-442	365	1	[	[	X
admet-442	365	2	79	79	NUM
admet-442	365	3	]	]	X
admet-442	365	4	f.	f.	PROPN
admet-442	365	5	bennett	bennett	PROPN
admet-442	365	6	,	,	PUNCT
admet-442	365	7	d.	d.	PROPN
admet-442	365	8	luxenberg	luxenberg	PROPN
admet-442	365	9	,	,	PUNCT
admet-442	365	10	v.	v.	PROPN
admet-442	365	11	ling	ling	PROPN
admet-442	365	12	,	,	PUNCT
admet-442	365	13	i.m	i.m	PROPN
admet-442	365	14	.	.	PROPN
admet-442	365	15	wang	wang	PROPN
admet-442	365	16	,	,	PUNCT
admet-442	365	17	k.	k.	PROPN
admet-442	365	18	marquette	marquette	PROPN
admet-442	365	19	,	,	PUNCT
admet-442	365	20	d.	d.	PROPN
admet-442	365	21	lowe	lowe	PROPN
admet-442	365	22	,	,	PUNCT
admet-442	365	23	n.	n.	PROPN
admet-442	365	24	khan	khan	PROPN
admet-442	365	25	,	,	PUNCT
admet-442	365	26	g.	g.	PROPN
admet-442	365	27	veldman	veldman	PROPN
admet-442	365	28	,	,	PUNCT
admet-442	365	29	k.a	k.a	PROPN
admet-442	365	30	.	.	PROPN
admet-442	365	31	jacobs	jacobs	PROPN
admet-442	365	32	,	,	PUNCT
admet-442	365	33	v.e	v.e	PROPN
admet-442	365	34	.	.	PROPN
admet-442	365	35	valge	valge	PROPN
admet-442	365	36	-	-	PUNCT
admet-442	365	37	archer	archer	ADJ
admet-442	365	38	,	,	PUNCT
admet-442	365	39	m.	m.	NOUN
admet-442	365	40	collins	collins	PROPN
admet-442	365	41	,	,	PUNCT
admet-442	365	42	b.m	b.m	PROPN
admet-442	365	43	.	.	PROPN
admet-442	365	44	carreno	carreno	PROPN
admet-442	365	45	.	.	PUNCT
admet-442	366	1	program	program	NOUN
admet-442	366	2	death-1	death-1	PROPN
admet-442	366	3	engagement	engagement	NOUN
admet-442	366	4	upon	upon	SCONJ
admet-442	366	5	tcr	tcr	PROPN
admet-442	366	6	activation	activation	NOUN
admet-442	366	7	has	have	VERB
admet-442	366	8	distinct	distinct	ADJ
admet-442	366	9	effects	effect	NOUN
admet-442	366	10	on	on	ADP
admet-442	366	11	costimulation	costimulation	NOUN
admet-442	366	12	and	and	CCONJ
admet-442	366	13	cytokine	cytokine	NOUN
admet-442	366	14	-	-	PUNCT
admet-442	366	15	driven	drive	VERB
admet-442	366	16	proliferation	proliferation	NOUN
admet-442	366	17	:	:	PUNCT
admet-442	366	18	attenuation	attenuation	NOUN
admet-442	366	19	of	of	ADP
admet-442	366	20	icos	icos	PROPN
admet-442	366	21	,	,	PUNCT
admet-442	366	22	il-4	il-4	X
admet-442	366	23	,	,	PUNCT
admet-442	366	24	and	and	CCONJ
admet-442	366	25	il-21	il-21	NOUN
admet-442	366	26	,	,	PUNCT
admet-442	366	27	but	but	CCONJ
admet-442	366	28	not	not	PART
admet-442	366	29	cd28	cd28	PROPN
admet-442	366	30	,	,	PUNCT
admet-442	366	31	il-7	il-7	X
admet-442	366	32	,	,	PUNCT
admet-442	366	33	and	and	CCONJ
admet-442	366	34	il-15	il-15	NOUN
admet-442	366	35	responses	response	NOUN
admet-442	366	36	,	,	PUNCT
admet-442	366	37	journal	journal	NOUN
admet-442	366	38	of	of	ADP
admet-442	366	39	immunology	immunology	NOUN
admet-442	366	40	170	170	NUM
admet-442	366	41	(	(	PUNCT
admet-442	366	42	2003	2003	NUM
admet-442	366	43	)	)	PUNCT
admet-442	366	44	711	711	NUM
admet-442	366	45	-	-	SYM
admet-442	366	46	718	718	NUM
admet-442	366	47	.	.	PUNCT
admet-442	367	1	[	[	X
admet-442	367	2	80	80	NUM
admet-442	367	3	]	]	X
admet-442	367	4	m.e	m.e	PROPN
admet-442	367	5	.	.	PROPN
admet-442	367	6	keir	keir	PROPN
admet-442	367	7	,	,	PUNCT
admet-442	367	8	m.j	m.j	PROPN
admet-442	367	9	.	.	PROPN
admet-442	367	10	butte	butte	PROPN
admet-442	367	11	,	,	PUNCT
admet-442	367	12	g.j	g.j	PROPN
admet-442	367	13	.	.	PROPN
admet-442	367	14	freeman	freeman	PROPN
admet-442	367	15	,	,	PUNCT
admet-442	367	16	a.h	a.h	PROPN
admet-442	367	17	.	.	PROPN
admet-442	367	18	sharpel	sharpel	PROPN
admet-442	367	19	.	.	PUNCT
admet-442	367	20	pd-1	pd-1	ADP
admet-442	367	21	and	and	CCONJ
admet-442	367	22	its	its	PRON
admet-442	367	23	ligands	ligand	NOUN
admet-442	367	24	in	in	ADP
admet-442	367	25	tolerance	tolerance	NOUN
admet-442	367	26	and	and	CCONJ
admet-442	367	27	immunity	immunity	NOUN
admet-442	367	28	,	,	PUNCT
admet-442	367	29	annu	annu	NOUN
admet-442	367	30	rev	rev	VERB
admet-442	367	31	immunol	immunol	NOUN
admet-442	367	32	26	26	NUM
admet-442	367	33	(	(	PUNCT
admet-442	367	34	2008	2008	NUM
admet-442	367	35	)	)	PUNCT
admet-442	367	36	677	677	NUM
admet-442	367	37	-	-	SYM
admet-442	367	38	704	704	NUM
admet-442	367	39	.	.	PUNCT
admet-442	368	1	[	[	X
admet-442	368	2	81	81	NUM
admet-442	368	3	]	]	PUNCT
admet-442	368	4	k.	k.	PROPN
admet-442	368	5	karwacz	karwacz	PROPN
admet-442	368	6	,	,	PUNCT
admet-442	368	7	f.	f.	PROPN
admet-442	368	8	arce	arce	PROPN
admet-442	368	9	,	,	PUNCT
admet-442	368	10	c.	c.	PROPN
admet-442	368	11	bricogne	bricogne	PROPN
admet-442	368	12	,	,	PUNCT
admet-442	368	13	g.	g.	PROPN
admet-442	368	14	kochan	kochan	PROPN
admet-442	368	15	,	,	PUNCT
admet-442	368	16	d.	d.	PROPN
admet-442	368	17	escors	escor	NOUN
admet-442	368	18	.	.	PUNCT
admet-442	369	1	pd	pd	PROPN
admet-442	369	2	-	-	PROPN
admet-442	369	3	l1	l1	PROPN
admet-442	369	4	co	co	NOUN
admet-442	369	5	-	-	NOUN
admet-442	369	6	stimulation	stimulation	ADJ
admet-442	369	7	,	,	PUNCT
admet-442	369	8	ligand	ligand	NOUN
admet-442	369	9	-	-	PUNCT
admet-442	369	10	induced	induce	VERB
admet-442	369	11	tcr	tcr	PROPN
admet-442	369	12	down	down	ADP
admet-442	369	13	-	-	PUNCT
admet-442	369	14	modulation	modulation	NOUN
admet-442	369	15	and	and	CCONJ
admet-442	369	16	anti	anti	ADJ
admet-442	369	17	-	-	ADJ
admet-442	369	18	tumor	tumor	ADJ
admet-442	369	19	immunotherapy	immunotherapy	NOUN
admet-442	369	20	,	,	PUNCT
admet-442	369	21	oncoimmunology	oncoimmunology	NOUN
admet-442	369	22	1	1	NUM
admet-442	369	23	(	(	PUNCT
admet-442	369	24	2012	2012	NUM
admet-442	369	25	)	)	PUNCT
admet-442	369	26	86	86	NUM
admet-442	369	27	-	-	SYM
admet-442	369	28	88	88	NUM
admet-442	369	29	.	.	PUNCT
admet-442	370	1	[	[	X
admet-442	370	2	82	82	NUM
admet-442	370	3	]	]	X
admet-442	370	4	m.	m.	NOUN
admet-442	370	5	hebeisen	hebeisen	PROPN
admet-442	370	6	,	,	PUNCT
admet-442	370	7	l.	l.	PROPN
admet-442	370	8	baitsch	baitsch	PROPN
admet-442	370	9	,	,	PUNCT
admet-442	370	10	d.	d.	PROPN
admet-442	370	11	presotto	presotto	PROPN
admet-442	370	12	,	,	PUNCT
admet-442	370	13	p.	p.	NOUN
admet-442	370	14	baumgaertner	baumgaertner	NOUN
admet-442	370	15	,	,	PUNCT
admet-442	370	16	p.	p.	PROPN
admet-442	370	17	romero	romero	PROPN
admet-442	370	18	,	,	PUNCT
admet-442	370	19	o.	o.	PROPN
admet-442	370	20	michielin	michielin	PROPN
admet-442	370	21	,	,	PUNCT
admet-442	370	22	d.e	d.e	PROPN
admet-442	370	23	.	.	PROPN
admet-442	370	24	speiser	speiser	PROPN
admet-442	370	25	,	,	PUNCT
admet-442	370	26	n.	n.	NOUN
admet-442	370	27	rufer	rufer	NOUN
admet-442	370	28	.	.	PUNCT
admet-442	371	1	shp-1	shp-1	NOUN
admet-442	371	2	phosphatase	phosphatase	NOUN
admet-442	371	3	activity	activity	NOUN
admet-442	371	4	counteracts	counteract	VERB
admet-442	371	5	increased	increase	VERB
admet-442	371	6	t	t	NOUN
admet-442	371	7	cell	cell	NOUN
admet-442	371	8	receptor	receptor	NOUN
admet-442	371	9	affinity	affinity	NOUN
admet-442	371	10	,	,	PUNCT
admet-442	371	11	journal	journal	NOUN
admet-442	371	12	of	of	ADP
admet-442	371	13	clinical	clinical	ADJ
admet-442	371	14	investigation	investigation	NOUN
admet-442	371	15	123	123	NUM
admet-442	371	16	(	(	PUNCT
admet-442	371	17	2013	2013	NUM
admet-442	371	18	)	)	PUNCT
admet-442	371	19	1044	1044	NUM
admet-442	371	20	-	-	SYM
admet-442	371	21	1056	1056	NUM
admet-442	371	22	.	.	PUNCT
admet-442	372	1	[	[	X
admet-442	372	2	83	83	NUM
admet-442	372	3	]	]	X
admet-442	372	4	l.m	l.m	PROPN
admet-442	372	5	.	.	PROPN
admet-442	372	6	shlapatska	shlapatska	PROPN
admet-442	372	7	,	,	PUNCT
admet-442	372	8	s.v	s.v	PROPN
admet-442	372	9	.	.	PROPN
admet-442	372	10	mikhalap	mikhalap	PROPN
admet-442	372	11	,	,	PUNCT
admet-442	372	12	a.g	a.g	PROPN
admet-442	372	13	.	.	PROPN
admet-442	372	14	berdova	berdova	PROPN
admet-442	372	15	,	,	PUNCT
admet-442	372	16	o.m	o.m	PROPN
admet-442	372	17	.	.	PUNCT
admet-442	373	1	zelensky	zelensky	PROPN
admet-442	373	2	,	,	PUNCT
admet-442	373	3	t.j	t.j	PROPN
admet-442	373	4	.	.	PROPN
admet-442	373	5	yun	yun	PROPN
admet-442	373	6	,	,	PUNCT
admet-442	373	7	k.e	k.e	PROPN
admet-442	373	8	.	.	PROPN
admet-442	373	9	nichols	nichols	PROPN
admet-442	373	10	,	,	PUNCT
admet-442	373	11	e.a	e.a	PROPN
admet-442	373	12	.	.	PROPN
admet-442	373	13	clark	clark	PROPN
admet-442	373	14	,	,	PUNCT
admet-442	373	15	s.p	s.p	PROPN
admet-442	373	16	.	.	PROPN
admet-442	373	17	sidorenko	sidorenko	PROPN
admet-442	373	18	.	.	PUNCT
admet-442	374	1	cd150	cd150	PROPN
admet-442	374	2	association	association	NOUN
admet-442	374	3	with	with	ADP
admet-442	374	4	either	either	CCONJ
admet-442	374	5	the	the	DET
admet-442	374	6	sh2	sh2	NOUN
admet-442	374	7	-	-	PUNCT
admet-442	374	8	containing	contain	VERB
admet-442	374	9	inositol	inositol	NOUN
admet-442	374	10	phosphatase	phosphatase	NOUN
admet-442	374	11	or	or	CCONJ
admet-442	374	12	the	the	DET
admet-442	374	13	sh2containing	sh2containing	ADJ
admet-442	374	14	protein	protein	NOUN
admet-442	374	15	tyrosine	tyrosine	NOUN
admet-442	374	16	phosphatase	phosphatase	NOUN
admet-442	374	17	is	be	AUX
admet-442	374	18	regulated	regulate	VERB
admet-442	374	19	by	by	ADP
admet-442	374	20	the	the	DET
admet-442	374	21	adaptor	adaptor	NOUN
admet-442	374	22	protein	protein	NOUN
admet-442	374	23	sh2d1a	sh2d1a	PROPN
admet-442	374	24	,	,	PUNCT
admet-442	374	25	journal	journal	NOUN
admet-442	374	26	of	of	ADP
admet-442	374	27	immunology	immunology	NOUN
admet-442	374	28	166	166	NUM
admet-442	374	29	(	(	PUNCT
admet-442	374	30	2001	2001	NUM
admet-442	374	31	)	)	PUNCT
admet-442	374	32	5480	5480	NUM
admet-442	374	33	-	-	SYM
admet-442	374	34	5487	5487	NUM
admet-442	374	35	.	.	PUNCT
admet-442	375	1	[	[	X
admet-442	375	2	84	84	NUM
admet-442	375	3	]	]	X
admet-442	375	4	j.m	j.m	PROPN
admet-442	375	5	.	.	PROPN
admet-442	375	6	chemnitz	chemnitz	PROPN
admet-442	375	7	,	,	PUNCT
admet-442	375	8	r.v	r.v	PROPN
admet-442	375	9	.	.	PROPN
admet-442	375	10	parry	parry	PROPN
admet-442	375	11	,	,	PUNCT
admet-442	375	12	k.e	k.e	PROPN
admet-442	375	13	.	.	PROPN
admet-442	375	14	nichols	nichols	PROPN
admet-442	375	15	,	,	PUNCT
admet-442	375	16	c.h	c.h	PROPN
admet-442	375	17	.	.	PROPN
admet-442	375	18	june	june	PROPN
admet-442	375	19	,	,	PUNCT
admet-442	375	20	j.l	j.l	PROPN
admet-442	375	21	.	.	PROPN
admet-442	375	22	riley	riley	PROPN
admet-442	375	23	.	.	PUNCT
admet-442	375	24	shp-1	shp-1	NOUN
admet-442	375	25	and	and	CCONJ
admet-442	375	26	shp-2	shp-2	VERB
admet-442	375	27	associate	associate	NOUN
admet-442	375	28	with	with	ADP
admet-442	375	29	immunoreceptor	immunoreceptor	NOUN
admet-442	375	30	tyrosine	tyrosine	NOUN
admet-442	375	31	-	-	PUNCT
admet-442	375	32	based	base	VERB
admet-442	375	33	switch	switch	NOUN
admet-442	375	34	motif	motif	NOUN
admet-442	375	35	of	of	ADP
admet-442	375	36	programmed	program	VERB
admet-442	375	37	death	death	NOUN
admet-442	375	38	1	1	NUM
admet-442	375	39	upon	upon	SCONJ
admet-442	375	40	primary	primary	ADJ
admet-442	375	41	human	human	PROPN
admet-442	375	42	t	t	PROPN
admet-442	375	43	cell	cell	NOUN
admet-442	375	44	stimulation	stimulation	NOUN
admet-442	375	45	,	,	PUNCT
admet-442	375	46	but	but	CCONJ
admet-442	375	47	only	only	ADV
admet-442	375	48	receptor	receptor	NOUN
admet-442	375	49	ligation	ligation	NOUN
admet-442	375	50	prevents	prevent	VERB
admet-442	375	51	t	t	NOUN
admet-442	375	52	cell	cell	NOUN
admet-442	375	53	activation	activation	NOUN
admet-442	375	54	,	,	PUNCT
admet-442	375	55	journal	journal	NOUN
admet-442	375	56	of	of	ADP
admet-442	375	57	immunology	immunology	NOUN
admet-442	375	58	173	173	NUM
admet-442	375	59	(	(	PUNCT
admet-442	375	60	2004	2004	NUM
admet-442	375	61	)	)	PUNCT
admet-442	375	62	945	945	NUM
admet-442	375	63	-	-	SYM
admet-442	375	64	954	954	NUM
admet-442	375	65	.	.	PUNCT
admet-442	376	1	[	[	X
admet-442	376	2	85	85	NUM
admet-442	376	3	]	]	X
admet-442	376	4	b.t	b.t	PROPN
admet-442	376	5	.	.	PROPN
admet-442	376	6	fife	fife	PROPN
admet-442	376	7	,	,	PUNCT
admet-442	376	8	k.e	k.e	PROPN
admet-442	376	9	.	.	PROPN
admet-442	376	10	pauken	pauken	PROPN
admet-442	376	11	,	,	PUNCT
admet-442	376	12	t.n	t.n	PROPN
admet-442	376	13	.	.	PROPN
admet-442	376	14	eagar	eagar	PROPN
admet-442	376	15	,	,	PUNCT
admet-442	376	16	t.	t.	PROPN
admet-442	376	17	obu	obu	PROPN
admet-442	376	18	,	,	PUNCT
admet-442	376	19	j.	j.	PROPN
admet-442	376	20	wu	wu	PROPN
admet-442	376	21	,	,	PUNCT
admet-442	376	22	q.z	q.z	PROPN
admet-442	376	23	.	.	PROPN
admet-442	376	24	tang	tang	PROPN
admet-442	376	25	,	,	PUNCT
admet-442	376	26	m.	m.	NOUN
admet-442	376	27	azuma	azuma	PROPN
admet-442	376	28	,	,	PUNCT
admet-442	376	29	m.f	m.f	PROPN
admet-442	376	30	.	.	PROPN
admet-442	376	31	krummel	krummel	PROPN
admet-442	376	32	,	,	PUNCT
admet-442	376	33	j.a	j.a	PROPN
admet-442	376	34	.	.	PROPN
admet-442	376	35	bluestone	bluestone	NOUN
admet-442	376	36	.	.	PUNCT
admet-442	377	1	interactions	interaction	NOUN
admet-442	377	2	between	between	ADP
admet-442	377	3	pd-1	pd-1	ADJ
admet-442	377	4	and	and	CCONJ
admet-442	377	5	pd	pd	PROPN
admet-442	377	6	-	-	PROPN
admet-442	377	7	l1	l1	PROPN
admet-442	377	8	promote	promote	VERB
admet-442	377	9	tolerance	tolerance	NOUN
admet-442	377	10	by	by	ADP
admet-442	377	11	blocking	block	VERB
admet-442	377	12	the	the	DET
admet-442	377	13	tcr	tcr	PROPN
admet-442	377	14	-	-	PUNCT
admet-442	377	15	induced	induce	VERB
admet-442	377	16	stop	stop	NOUN
admet-442	377	17	signal	signal	NOUN
admet-442	377	18	,	,	PUNCT
admet-442	377	19	nat	nat	PROPN
admet-442	377	20	immunol	immunol	NOUN
admet-442	377	21	10	10	NUM
admet-442	377	22	(	(	PUNCT
admet-442	377	23	2009	2009	NUM
admet-442	377	24	)	)	PUNCT
admet-442	377	25	1185	1185	NUM
admet-442	377	26	-	-	PUNCT
admet-442	377	27	u1170	u1170	NOUN
admet-442	377	28	.	.	PUNCT
admet-442	378	1	[	[	X
admet-442	378	2	86	86	NUM
admet-442	378	3	]	]	X
admet-442	378	4	n.	n.	NOUN
admet-442	378	5	patsoukis	patsoukis	PROPN
admet-442	378	6	,	,	PUNCT
admet-442	378	7	j.	j.	PROPN
admet-442	378	8	brown	brown	PROPN
admet-442	378	9	,	,	PUNCT
admet-442	378	10	v.	v.	CCONJ
admet-442	378	11	petkova	petkova	PROPN
admet-442	378	12	,	,	PUNCT
admet-442	378	13	f.	f.	PROPN
admet-442	378	14	liu	liu	PROPN
admet-442	378	15	,	,	PUNCT
admet-442	378	16	l.	l.	PROPN
admet-442	378	17	li	li	PROPN
admet-442	378	18	,	,	PUNCT
admet-442	378	19	v.a	v.a	PROPN
admet-442	378	20	.	.	PROPN
admet-442	378	21	boussiotis	boussiotis	PROPN
admet-442	378	22	.	.	PUNCT
admet-442	379	1	selective	selective	ADJ
admet-442	379	2	effects	effect	NOUN
admet-442	379	3	of	of	ADP
admet-442	379	4	pd-1	pd-1	VERB
admet-442	379	5	on	on	ADP
admet-442	379	6	akt	akt	PROPN
admet-442	379	7	and	and	CCONJ
admet-442	379	8	ras	ras	PROPN
admet-442	379	9	pathways	pathway	NOUN
admet-442	379	10	regulate	regulate	VERB
admet-442	379	11	molecular	molecular	ADJ
admet-442	379	12	components	component	NOUN
admet-442	379	13	of	of	ADP
admet-442	379	14	the	the	DET
admet-442	379	15	cell	cell	NOUN
admet-442	379	16	cycle	cycle	NOUN
admet-442	379	17	and	and	CCONJ
admet-442	379	18	inhibit	inhibit	VERB
admet-442	379	19	t	t	PROPN
admet-442	379	20	cell	cell	NOUN
admet-442	379	21	proliferation	proliferation	NOUN
admet-442	379	22	,	,	PUNCT
admet-442	379	23	sci	sci	PROPN
admet-442	379	24	signal	signal	NOUN
admet-442	379	25	5	5	NUM
admet-442	379	26	(	(	PUNCT
admet-442	379	27	2012	2012	NUM
admet-442	379	28	)	)	PUNCT
admet-442	380	1	ra46	ra46	PROPN
admet-442	380	2	.	.	PUNCT
admet-442	381	1	[	[	X
admet-442	381	2	87	87	NUM
admet-442	381	3	]	]	PUNCT
admet-442	381	4	r.	r.	PROPN
admet-442	381	5	nurieva	nurieva	PROPN
admet-442	381	6	,	,	PUNCT
admet-442	381	7	s.	s.	PROPN
admet-442	381	8	thomas	thomas	PROPN
admet-442	381	9	,	,	PUNCT
admet-442	381	10	t.	t.	PROPN
admet-442	381	11	nguyen	nguyen	PROPN
admet-442	381	12	,	,	PUNCT
admet-442	381	13	n.	n.	PROPN
admet-442	381	14	martin	martin	PROPN
admet-442	381	15	-	-	PUNCT
admet-442	381	16	orozco	orozco	PROPN
admet-442	381	17	,	,	PUNCT
admet-442	381	18	y.	y.	PROPN
admet-442	381	19	wang	wang	PROPN
admet-442	381	20	,	,	PUNCT
admet-442	381	21	m.k	m.k	PROPN
admet-442	381	22	.	.	PROPN
admet-442	381	23	kaja	kaja	PROPN
admet-442	381	24	,	,	PUNCT
admet-442	381	25	x.z	x.z	PROPN
admet-442	381	26	.	.	PROPN
admet-442	381	27	yu	yu	PROPN
admet-442	381	28	,	,	PUNCT
admet-442	381	29	c.	c.	PROPN
admet-442	381	30	dong	dong	PROPN
admet-442	381	31	.	.	PUNCT
admet-442	382	1	t	t	PROPN
admet-442	382	2	-	-	PUNCT
admet-442	382	3	cell	cell	NOUN
admet-442	382	4	tolerance	tolerance	NOUN
admet-442	382	5	or	or	CCONJ
admet-442	382	6	function	function	NOUN
admet-442	382	7	is	be	AUX
admet-442	382	8	determined	determine	VERB
admet-442	382	9	by	by	ADP
admet-442	382	10	combinatorial	combinatorial	ADJ
admet-442	382	11	costimulatory	costimulatory	NOUN
admet-442	382	12	signals	signal	NOUN
admet-442	382	13	,	,	PUNCT
admet-442	382	14	embo	embo	NOUN
admet-442	382	15	j	j	PROPN
admet-442	382	16	25	25	NUM
admet-442	382	17	(	(	PUNCT
admet-442	382	18	2006	2006	NUM
admet-442	382	19	)	)	PUNCT
admet-442	382	20	2623	2623	NUM
admet-442	382	21	-	-	SYM
admet-442	382	22	2633	2633	NUM
admet-442	382	23	.	.	PUNCT
admet-442	383	1	[	[	X
admet-442	383	2	88	88	NUM
admet-442	383	3	]	]	X
admet-442	383	4	d.m	d.m	PROPN
admet-442	383	5	.	.	PUNCT
admet-442	383	6	dorfman	dorfman	PROPN
admet-442	383	7	,	,	PUNCT
admet-442	383	8	e.s	e.s	PROPN
admet-442	383	9	.	.	PROPN
admet-442	383	10	hwang	hwang	PROPN
admet-442	383	11	,	,	PUNCT
admet-442	383	12	a.	a.	PROPN
admet-442	383	13	shahsafaei	shahsafaei	PROPN
admet-442	383	14	,	,	PUNCT
admet-442	383	15	l.h	l.h	PROPN
admet-442	383	16	.	.	PROPN
admet-442	383	17	glimcher	glimcher	PROPN
admet-442	383	18	.	.	PUNCT
admet-442	384	1	t	t	PROPN
admet-442	384	2	-	-	PUNCT
admet-442	384	3	bet	bet	NOUN
admet-442	384	4	,	,	PUNCT
admet-442	384	5	a	a	DET
admet-442	384	6	t	t	NOUN
admet-442	384	7	cell	cell	NOUN
admet-442	384	8	-	-	PUNCT
admet-442	384	9	associated	associate	VERB
admet-442	384	10	transcription	transcription	NOUN
admet-442	384	11	factor	factor	NOUN
admet-442	384	12	,	,	PUNCT
admet-442	384	13	is	be	AUX
admet-442	384	14	expressed	express	VERB
admet-442	384	15	in	in	ADP
admet-442	384	16	hodgkin	hodgkin	PROPN
admet-442	384	17	's	's	PART
admet-442	384	18	lymphoma	lymphoma	NOUN
admet-442	384	19	,	,	PUNCT
admet-442	384	20	hum	hum	ADJ
admet-442	384	21	pathol	pathol	NOUN
admet-442	384	22	36	36	NUM
admet-442	384	23	(	(	PUNCT
admet-442	384	24	2005	2005	NUM
admet-442	384	25	)	)	PUNCT
admet-442	384	26	10	10	NUM
admet-442	384	27	-	-	SYM
admet-442	384	28	15	15	NUM
admet-442	384	29	.	.	PUNCT
admet-442	385	1	[	[	X
admet-442	385	2	89	89	NUM
admet-442	385	3	]	]	X
admet-442	385	4	l.m	l.m	PROPN
admet-442	385	5	.	.	PROPN
admet-442	385	6	francisco	francisco	PROPN
admet-442	385	7	,	,	PUNCT
admet-442	385	8	v.h	v.h	PROPN
admet-442	385	9	.	.	PROPN
admet-442	385	10	salinas	salinas	PROPN
admet-442	385	11	,	,	PUNCT
admet-442	385	12	k.e	k.e	PROPN
admet-442	385	13	.	.	PROPN
admet-442	385	14	brown	brown	PROPN
admet-442	385	15	,	,	PUNCT
admet-442	385	16	v.k	v.k	PROPN
admet-442	385	17	.	.	PROPN
admet-442	385	18	vanguri	vanguri	PROPN
admet-442	385	19	,	,	PUNCT
admet-442	385	20	g.j	g.j	PROPN
admet-442	385	21	.	.	PROPN
admet-442	385	22	freeman	freeman	PROPN
admet-442	385	23	,	,	PUNCT
admet-442	385	24	v.k	v.k	PROPN
admet-442	385	25	.	.	PROPN
admet-442	385	26	kuchroo	kuchroo	PROPN
admet-442	385	27	,	,	PUNCT
admet-442	385	28	a.h	a.h	PROPN
admet-442	385	29	.	.	PROPN
admet-442	385	30	sharpe	sharpe	PROPN
admet-442	385	31	.	.	PROPN
admet-442	386	1	pdl1	pdl1	PROPN
admet-442	386	2	regulates	regulate	VERB
admet-442	386	3	the	the	DET
admet-442	386	4	development	development	NOUN
admet-442	386	5	,	,	PUNCT
admet-442	386	6	maintenance	maintenance	NOUN
admet-442	386	7	,	,	PUNCT
admet-442	386	8	and	and	CCONJ
admet-442	386	9	function	function	NOUN
admet-442	386	10	of	of	ADP
admet-442	386	11	induced	induced	ADJ
admet-442	386	12	regulatory	regulatory	ADJ
admet-442	386	13	t	t	NOUN
admet-442	386	14	cells	cell	NOUN
admet-442	386	15	,	,	PUNCT
admet-442	386	16	journal	journal	NOUN
admet-442	386	17	of	of	ADP
admet-442	386	18	experimental	experimental	ADJ
admet-442	386	19	medicine	medicine	NOUN
admet-442	386	20	206	206	NUM
admet-442	386	21	(	(	PUNCT
admet-442	386	22	2009	2009	NUM
admet-442	386	23	)	)	PUNCT
admet-442	386	24	3015	3015	NUM
admet-442	386	25	-	-	SYM
admet-442	386	26	3029	3029	NUM
admet-442	386	27	.	.	PUNCT
admet-442	387	1	[	[	X
admet-442	387	2	90	90	NUM
admet-442	387	3	]	]	SYM
admet-442	387	4	l.l	l.l	PROPN
admet-442	387	5	.	.	PROPN
admet-442	387	6	carter	carter	PROPN
admet-442	387	7	,	,	PUNCT
admet-442	387	8	l.a	l.a	PROPN
admet-442	387	9	.	.	PROPN
admet-442	387	10	fouser	fouser	PROPN
admet-442	387	11	,	,	PUNCT
admet-442	387	12	j.	j.	PROPN
admet-442	387	13	jussif	jussif	PROPN
admet-442	387	14	,	,	PUNCT
admet-442	387	15	l.	l.	PROPN
admet-442	387	16	fitz	fitz	PROPN
admet-442	387	17	,	,	PUNCT
admet-442	387	18	b.	b.	PROPN
admet-442	387	19	deng	deng	PROPN
admet-442	387	20	,	,	PUNCT
admet-442	387	21	c.r	c.r	PROPN
admet-442	387	22	.	.	PROPN
admet-442	387	23	wood	wood	PROPN
admet-442	387	24	,	,	PUNCT
admet-442	387	25	m.	m.	NOUN
admet-442	387	26	collins	collins	PROPN
admet-442	387	27	,	,	PUNCT
admet-442	387	28	t.	t.	PROPN
admet-442	387	29	honjo	honjo	PROPN
admet-442	387	30	,	,	PUNCT
admet-442	387	31	g.j	g.j	PROPN
admet-442	387	32	.	.	PROPN
admet-442	387	33	freeman	freeman	PROPN
admet-442	387	34	,	,	PUNCT
admet-442	387	35	b.m	b.m	PROPN
admet-442	387	36	.	.	PROPN
admet-442	387	37	carreno	carreno	PROPN
admet-442	387	38	.	.	PUNCT
admet-442	388	1	pd-1	pd-1	ADP
admet-442	388	2	:	:	PUNCT
admet-442	388	3	pd	pd	ADJ
admet-442	388	4	-	-	ADJ
admet-442	388	5	l	l	NOUN
admet-442	388	6	inhibitory	inhibitory	ADJ
admet-442	388	7	pathway	pathway	NOUN
admet-442	388	8	affects	affect	VERB
admet-442	388	9	both	both	DET
admet-442	388	10	cd4(+)and	cd4(+)and	ADV
admet-442	388	11	cd8(+	cd8(+	PROPN
admet-442	388	12	)	)	PUNCT
admet-442	388	13	t	t	NOUN
admet-442	388	14	cells	cell	NOUN
admet-442	388	15	and	and	CCONJ
admet-442	388	16	is	be	AUX
admet-442	388	17	overcome	overcome	VERB
admet-442	388	18	by	by	ADP
admet-442	388	19	il-2	il-2	NOUN
admet-442	388	20	,	,	PUNCT
admet-442	388	21	european	european	ADJ
admet-442	388	22	journal	journal	NOUN
admet-442	388	23	of	of	ADP
admet-442	388	24	immunology	immunology	NOUN
admet-442	388	25	32	32	NUM
admet-442	388	26	(	(	PUNCT
admet-442	388	27	2002	2002	NUM
admet-442	388	28	)	)	PUNCT
admet-442	388	29	634	634	NUM
admet-442	388	30	-	-	SYM
admet-442	388	31	643	643	NUM
admet-442	388	32	.	.	PUNCT
admet-442	389	1	[	[	X
admet-442	389	2	91	91	NUM
admet-442	389	3	]	]	X
admet-442	389	4	n.	n.	NOUN
admet-442	389	5	rodig	rodig	PROPN
admet-442	389	6	,	,	PUNCT
admet-442	389	7	t.	t.	PROPN
admet-442	389	8	ryan	ryan	PROPN
admet-442	389	9	,	,	PUNCT
admet-442	389	10	j.a	j.a	PROPN
admet-442	389	11	.	.	PROPN
admet-442	389	12	allen	allen	PROPN
admet-442	389	13	,	,	PUNCT
admet-442	389	14	h.	h.	PROPN
admet-442	389	15	pang	pang	PROPN
admet-442	389	16	,	,	PUNCT
admet-442	389	17	n.	n.	NOUN
admet-442	389	18	grabie	grabie	PROPN
admet-442	389	19	,	,	PUNCT
admet-442	389	20	t.	t.	PROPN
admet-442	389	21	chernova	chernova	PROPN
admet-442	389	22	,	,	PUNCT
admet-442	389	23	e.a	e.a	PROPN
admet-442	389	24	.	.	PROPN
admet-442	389	25	greenfield	greenfield	PROPN
admet-442	389	26	,	,	PUNCT
admet-442	389	27	s.c	s.c	PROPN
admet-442	389	28	.	.	PROPN
admet-442	389	29	liang	liang	PROPN
admet-442	389	30	,	,	PUNCT
admet-442	389	31	a.h	a.h	PROPN
admet-442	389	32	.	.	PROPN
admet-442	389	33	sharpe	sharpe	PROPN
admet-442	389	34	,	,	PUNCT
admet-442	389	35	a.h	a.h	PROPN
admet-442	389	36	.	.	PROPN
admet-442	389	37	lichtman	lichtman	PROPN
admet-442	389	38	,	,	PUNCT
admet-442	389	39	g.j	g.j	PROPN
admet-442	389	40	.	.	PROPN
admet-442	389	41	freeman	freeman	PROPN
admet-442	389	42	.	.	PUNCT
admet-442	390	1	endothelial	endothelial	ADJ
admet-442	390	2	expression	expression	NOUN
admet-442	390	3	of	of	ADP
admet-442	390	4	pd	pd	PROPN
admet-442	390	5	-	-	PROPN
admet-442	390	6	l1	l1	PROPN
admet-442	390	7	and	and	CCONJ
admet-442	390	8	pd	pd	NOUN
admet-442	390	9	-	-	PUNCT
admet-442	390	10	l2	l2	NOUN
admet-442	390	11	down	down	ADV
admet-442	390	12	-	-	PUNCT
admet-442	390	13	regulates	regulate	VERB
admet-442	390	14	cd8	cd8	PROPN
admet-442	390	15	+	+	PROPN
admet-442	390	16	t	t	NOUN
admet-442	390	17	cell	cell	NOUN
admet-442	390	18	activation	activation	NOUN
admet-442	390	19	and	and	CCONJ
admet-442	390	20	cytolysis	cytolysis	NOUN
admet-442	390	21	,	,	PUNCT
admet-442	390	22	eur	eur	PROPN
admet-442	390	23	j	j	PROPN
admet-442	390	24	immunol	immunol	NOUN
admet-442	390	25	33	33	NUM
admet-442	390	26	(	(	PUNCT
admet-442	390	27	2003	2003	NUM
admet-442	390	28	)	)	PUNCT
admet-442	390	29	3117	3117	NUM
admet-442	390	30	-	-	PUNCT
admet-442	390	31	3126	3126	NUM
admet-442	390	32	.	.	PUNCT
admet-442	391	1	[	[	X
admet-442	391	2	92	92	NUM
admet-442	391	3	]	]	PUNCT
admet-442	391	4	r.	r.	PROPN
admet-442	391	5	yamamoto	yamamoto	PROPN
admet-442	391	6	,	,	PUNCT
admet-442	391	7	m.	m.	NOUN
admet-442	391	8	nishikori	nishikori	PROPN
admet-442	391	9	,	,	PUNCT
admet-442	391	10	t.	t.	PROPN
admet-442	391	11	kitawaki	kitawaki	PROPN
admet-442	391	12	,	,	PUNCT
admet-442	391	13	t.	t.	PROPN
admet-442	391	14	sakai	sakai	PROPN
admet-442	391	15	,	,	PUNCT
admet-442	391	16	m.	m.	NOUN
admet-442	391	17	hishizawa	hishizawa	PROPN
admet-442	391	18	,	,	PUNCT
admet-442	391	19	m.	m.	NOUN
admet-442	391	20	tashima	tashima	PROPN
admet-442	391	21	,	,	PUNCT
admet-442	391	22	t.	t.	PROPN
admet-442	391	23	kondo	kondo	PROPN
admet-442	391	24	,	,	PUNCT
admet-442	391	25	k.	k.	PROPN
admet-442	391	26	ohmori	ohmori	PROPN
admet-442	391	27	,	,	PUNCT
admet-442	391	28	m.	m.	NOUN
admet-442	391	29	kurata	kurata	PROPN
admet-442	391	30	,	,	PUNCT
admet-442	391	31	t.	t.	PROPN
admet-442	391	32	hayashi	hayashi	PROPN
admet-442	391	33	,	,	PUNCT
admet-442	391	34	t.	t.	PROPN
admet-442	391	35	uchiyama	uchiyama	NOUN
admet-442	391	36	.	.	PUNCT
admet-442	392	1	pd-1	pd-1	NOUN
admet-442	392	2	-	-	PUNCT
admet-442	392	3	pd-1	pd-1	VERB
admet-442	392	4	ligand	ligand	ADJ
admet-442	392	5	interaction	interaction	NOUN
admet-442	392	6	contributes	contribute	VERB
admet-442	392	7	to	to	ADP
admet-442	392	8	immunosuppressive	immunosuppressive	ADJ
admet-442	392	9	microenvironment	microenvironment	NOUN
admet-442	392	10	of	of	ADP
admet-442	392	11	hodgkin	hodgkin	PROPN
admet-442	392	12	lymphoma	lymphoma	NOUN
admet-442	392	13	,	,	PUNCT
admet-442	392	14	blood	blood	NOUN
admet-442	392	15	111	111	NUM
admet-442	392	16	(	(	PUNCT
admet-442	392	17	2008	2008	NUM
admet-442	392	18	)	)	PUNCT
admet-442	392	19	3220	3220	NUM
admet-442	392	20	-	-	SYM
admet-442	392	21	3224	3224	NUM
admet-442	392	22	.	.	PUNCT
admet-442	393	1	guo	guo	PROPN
admet-442	393	2	,	,	PUNCT
admet-442	393	3	lin	lin	PROPN
admet-442	393	4	and	and	CCONJ
admet-442	393	5	kwok	kwok	PROPN
admet-442	393	6	admet	admet	PROPN
admet-442	393	7	&	&	CCONJ
admet-442	393	8	dmpk	dmpk	PROPN
admet-442	393	9	5(3	5(3	NUM
admet-442	393	10	)	)	PUNCT
admet-442	393	11	(	(	PUNCT
admet-442	393	12	2017	2017	NUM
admet-442	393	13	)	)	PUNCT
admet-442	393	14	159	159	NUM
admet-442	393	15	-	-	SYM
admet-442	393	16	172	172	NUM
admet-442	393	17	172	172	NUM
admet-442	394	1	[	[	X
admet-442	394	2	93	93	NUM
admet-442	394	3	]	]	X
admet-442	394	4	j.r	j.r	PROPN
admet-442	394	5	.	.	PROPN
admet-442	394	6	brahmer	brahmer	PROPN
admet-442	394	7	,	,	PUNCT
admet-442	394	8	s.s	s.s	PROPN
admet-442	394	9	.	.	PROPN
admet-442	394	10	tykodi	tykodi	PROPN
admet-442	394	11	,	,	PUNCT
admet-442	394	12	l.q	l.q	PROPN
admet-442	394	13	.	.	PROPN
admet-442	394	14	chow	chow	PROPN
admet-442	394	15	,	,	PUNCT
admet-442	394	16	w.j	w.j	PROPN
admet-442	394	17	.	.	PROPN
admet-442	394	18	hwu	hwu	PROPN
admet-442	394	19	,	,	PUNCT
admet-442	394	20	s.l	s.l	PROPN
admet-442	394	21	.	.	PROPN
admet-442	394	22	topalian	topalian	PROPN
admet-442	394	23	,	,	PUNCT
admet-442	394	24	p.	p.	PROPN
admet-442	394	25	hwu	hwu	PROPN
admet-442	394	26	,	,	PUNCT
admet-442	394	27	c.g	c.g	PROPN
admet-442	394	28	.	.	PROPN
admet-442	394	29	drake	drake	PROPN
admet-442	394	30	,	,	PUNCT
admet-442	394	31	l.h	l.h	PROPN
admet-442	394	32	.	.	PROPN
admet-442	394	33	camacho	camacho	PROPN
admet-442	394	34	,	,	PUNCT
admet-442	395	1	j.	j.	PROPN
admet-442	395	2	kauh	kauh	PROPN
admet-442	395	3	,	,	PUNCT
admet-442	395	4	k.	k.	PROPN
admet-442	395	5	odunsi	odunsi	PROPN
admet-442	395	6	,	,	PUNCT
admet-442	395	7	h.c	h.c	PROPN
admet-442	395	8	.	.	NOUN
admet-442	395	9	pitot	pitot	NOUN
admet-442	395	10	,	,	PUNCT
admet-442	395	11	o.	o.	PROPN
admet-442	395	12	hamid	hamid	PROPN
admet-442	395	13	,	,	PUNCT
admet-442	395	14	s.	s.	PROPN
admet-442	395	15	bhatia	bhatia	PROPN
admet-442	395	16	,	,	PUNCT
admet-442	395	17	r.	r.	PROPN
admet-442	395	18	martins	martins	PROPN
admet-442	395	19	,	,	PUNCT
admet-442	395	20	k.	k.	PROPN
admet-442	395	21	eaton	eaton	PROPN
admet-442	395	22	,	,	PUNCT
admet-442	395	23	s.	s.	PROPN
admet-442	395	24	chen	chen	PROPN
admet-442	395	25	,	,	PUNCT
admet-442	395	26	t.m	t.m	PROPN
admet-442	395	27	.	.	PROPN
admet-442	395	28	salay	salay	PROPN
admet-442	395	29	,	,	PUNCT
admet-442	395	30	s.	s.	PROPN
admet-442	395	31	alaparthy	alaparthy	PROPN
admet-442	395	32	,	,	PUNCT
admet-442	395	33	j.f	j.f	PROPN
admet-442	395	34	.	.	PROPN
admet-442	395	35	grosso	grosso	PROPN
admet-442	395	36	,	,	PUNCT
admet-442	395	37	a.j	a.j	PROPN
admet-442	395	38	.	.	PROPN
admet-442	395	39	korman	korman	PROPN
admet-442	395	40	,	,	PUNCT
admet-442	395	41	s.m	s.m	PROPN
admet-442	395	42	.	.	PROPN
admet-442	395	43	parker	parker	PROPN
admet-442	395	44	,	,	PUNCT
admet-442	395	45	s.	s.	PROPN
admet-442	395	46	agrawal	agrawal	PROPN
admet-442	395	47	,	,	PUNCT
admet-442	395	48	s.m	s.m	PROPN
admet-442	395	49	.	.	PROPN
admet-442	395	50	goldberg	goldberg	PROPN
admet-442	395	51	,	,	PUNCT
admet-442	395	52	d.m	d.m	PROPN
admet-442	395	53	.	.	PROPN
admet-442	395	54	pardoll	pardoll	PROPN
admet-442	395	55	,	,	PUNCT
admet-442	395	56	a.	a.	PROPN
admet-442	395	57	gupta	gupta	PROPN
admet-442	395	58	,	,	PUNCT
admet-442	395	59	j.m	j.m	PROPN
admet-442	395	60	.	.	PROPN
admet-442	395	61	wigginton	wigginton	PROPN
admet-442	395	62	.	.	PUNCT
admet-442	396	1	safety	safety	NOUN
admet-442	396	2	and	and	CCONJ
admet-442	396	3	activity	activity	NOUN
admet-442	396	4	of	of	ADP
admet-442	396	5	anti	anti	ADJ
admet-442	396	6	-	-	ADJ
admet-442	396	7	pd	pd	ADJ
admet-442	396	8	-	-	PUNCT
admet-442	396	9	l1	l1	PROPN
admet-442	396	10	antibody	antibody	NOUN
admet-442	396	11	in	in	ADP
admet-442	396	12	patients	patient	NOUN
admet-442	396	13	with	with	ADP
admet-442	396	14	advanced	advanced	ADJ
admet-442	396	15	cancer	cancer	NOUN
admet-442	396	16	,	,	PUNCT
admet-442	396	17	n	n	PROPN
admet-442	396	18	engl	engl	PROPN
admet-442	396	19	j	j	PROPN
admet-442	396	20	med	me	VERB
admet-442	396	21	366	366	NUM
admet-442	396	22	(	(	PUNCT
admet-442	396	23	2012	2012	NUM
admet-442	396	24	)	)	PUNCT
admet-442	396	25	2455	2455	NUM
admet-442	396	26	-	-	SYM
admet-442	396	27	2465	2465	NUM
admet-442	396	28	.	.	PUNCT
admet-442	397	1	©	©	NOUN
admet-442	397	2	2017	2017	NUM
admet-442	397	3	by	by	ADP
admet-442	397	4	the	the	DET
admet-442	397	5	authors	author	NOUN
admet-442	397	6	;	;	PUNCT
admet-442	397	7	licensee	licensee	PROPN
admet-442	397	8	iapc	iapc	PROPN
admet-442	397	9	,	,	PUNCT
admet-442	397	10	zagreb	zagreb	PROPN
admet-442	397	11	,	,	PUNCT
admet-442	397	12	croatia	croatia	PROPN
admet-442	397	13	.	.	PUNCT
admet-442	398	1	this	this	DET
admet-442	398	2	article	article	NOUN
admet-442	398	3	is	be	AUX
admet-442	398	4	an	an	DET
admet-442	398	5	open	open	ADJ
admet-442	398	6	-	-	PUNCT
admet-442	398	7	access	access	NOUN
admet-442	398	8	article	article	NOUN
admet-442	398	9	distributed	distribute	VERB
admet-442	398	10	under	under	ADP
admet-442	398	11	the	the	DET
admet-442	398	12	terms	term	NOUN
admet-442	398	13	and	and	CCONJ
admet-442	398	14	conditions	condition	NOUN
admet-442	398	15	of	of	ADP
admet-442	398	16	the	the	DET
admet-442	398	17	creative	creative	ADJ
admet-442	398	18	commons	common	NOUN
admet-442	398	19	attribution	attribution	NOUN
admet-442	398	20	license	license	NOUN
admet-442	398	21	(	(	PUNCT
admet-442	398	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-442	398	23	)	)	PUNCT
admet-442	398	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN