id	sid	tid	token	lemma	pos
admet-497	1	1	dissolution	dissolution	NOUN
admet-497	1	2	rates	rate	NOUN
admet-497	1	3	of	of	ADP
admet-497	1	4	ciprofloxacin	ciprofloxacin	PROPN
admet-497	1	5	and	and	CCONJ
admet-497	1	6	its	its	PRON
admet-497	1	7	cocrystal	cocrystal	NOUN
admet-497	1	8	with	with	ADP
admet-497	1	9	resorcinol	resorcinol	NOUN
admet-497	1	10	doi	doi	NOUN
admet-497	1	11	:	:	PUNCT
admet-497	1	12	10.5599	10.5599	NUM
admet-497	1	13	/	/	SYM
admet-497	1	14	admet.6.1.497	admet.6.1.497	PROPN
admet-497	1	15	61	61	NUM
admet-497	1	16	admet	admet	X
admet-497	1	17	&	&	CCONJ
admet-497	1	18	dmpk	dmpk	PROPN
admet-497	1	19	6(1	6(1	NUM
admet-497	1	20	)	)	PUNCT
admet-497	1	21	(	(	PUNCT
admet-497	1	22	2018	2018	NUM
admet-497	1	23	)	)	PUNCT
admet-497	1	24	61	61	NUM
admet-497	1	25	-	-	SYM
admet-497	1	26	70	70	NUM
admet-497	1	27	;	;	PUNCT
admet-497	1	28	doi	doi	NOUN
admet-497	1	29	:	:	PUNCT
admet-497	1	30	http://dx.doi.org/10.5599/admet.6.1.497	http://dx.doi.org/10.5599/admet.6.1.497	VERB
admet-497	1	31	open	open	ADJ
admet-497	1	32	access	access	NOUN
admet-497	1	33	:	:	PUNCT
admet-497	1	34	issn	issn	PROPN
admet-497	1	35	:	:	PUNCT
admet-497	1	36	1848	1848	NUM
admet-497	1	37	-	-	SYM
admet-497	1	38	7718	7718	NUM
admet-497	1	39	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-497	1	40	short	short	ADJ
admet-497	1	41	communication	communication	NOUN
admet-497	1	42	dissolution	dissolution	NOUN
admet-497	1	43	rates	rate	NOUN
admet-497	1	44	of	of	ADP
admet-497	1	45	ciprofloxacin	ciprofloxacin	PROPN
admet-497	1	46	and	and	CCONJ
admet-497	1	47	its	its	PRON
admet-497	1	48	cocrystal	cocrystal	NOUN
admet-497	1	49	with	with	ADP
admet-497	1	50	resorcinol	resorcinol	NOUN
admet-497	1	51	clara	clara	PROPN
admet-497	1	52	ràfols1	ràfols1	PROPN
admet-497	1	53	,	,	PUNCT
admet-497	1	54	*	*	PROPN
admet-497	1	55	,	,	PUNCT
admet-497	1	56	hanan	hanan	PROPN
admet-497	1	57	fael1	fael1	PROPN
admet-497	1	58	,	,	PUNCT
admet-497	1	59	elisabet	elisabet	ADJ
admet-497	1	60	fuguet1	fuguet1	PROPN
admet-497	1	61	,	,	PUNCT
admet-497	1	62	breeze	breeze	PROPN
admet-497	1	63	outhwaite2	outhwaite2	NOUN
admet-497	1	64	,	,	PUNCT
admet-497	1	65	samuel	samuel	PROPN
admet-497	1	66	lee2	lee2	PROPN
admet-497	1	67	,	,	PUNCT
admet-497	1	68	rebeca	rebeca	NOUN
admet-497	1	69	ruiz2	ruiz2	X
admet-497	1	70	1	1	NUM
admet-497	1	71	departament	departament	ADJ
admet-497	1	72	de	de	PROPN
admet-497	1	73	química	química	PROPN
admet-497	1	74	analítica	analítica	PROPN
admet-497	1	75	and	and	CCONJ
admet-497	1	76	institut	institut	PROPN
admet-497	1	77	de	de	PROPN
admet-497	1	78	biomedicina	biomedicina	PROPN
admet-497	1	79	(	(	PUNCT
admet-497	1	80	ibub	ibub	PROPN
admet-497	1	81	)	)	PUNCT
admet-497	1	82	,	,	PUNCT
admet-497	1	83	universitat	universitat	PROPN
admet-497	1	84	de	de	PROPN
admet-497	1	85	barcelona	barcelona	PROPN
admet-497	1	86	;	;	PUNCT
admet-497	1	87	martí	martí	NOUN
admet-497	1	88	i	i	PRON
admet-497	1	89	franquès	franquès	VERB
admet-497	1	90	111	111	NUM
admet-497	1	91	,	,	PUNCT
admet-497	1	92	08028	08028	NUM
admet-497	1	93	barcelona	barcelona	PROPN
admet-497	1	94	,	,	PUNCT
admet-497	1	95	spain	spain	PROPN
admet-497	1	96	2	2	NUM
admet-497	1	97	sirius	sirius	PROPN
admet-497	1	98	analytical	analytical	NOUN
admet-497	1	99	,	,	PUNCT
admet-497	1	100	forest	forest	NOUN
admet-497	1	101	row	row	NOUN
admet-497	1	102	,	,	PUNCT
admet-497	1	103	east	east	PROPN
admet-497	1	104	sussex	sussex	PROPN
admet-497	1	105	,	,	PUNCT
admet-497	1	106	uk	uk	PROPN
admet-497	1	107	*	*	PUNCT
admet-497	1	108	corresponding	correspond	VERB
admet-497	1	109	author	author	NOUN
admet-497	1	110	:	:	PUNCT
admet-497	1	111	e	e	NOUN
admet-497	1	112	-	-	NOUN
admet-497	1	113	mail	mail	NOUN
admet-497	1	114	:	:	PUNCT
admet-497	1	115	crafols@ub.edu	crafols@ub.edu	PROPN
admet-497	1	116	;	;	PUNCT
admet-497	1	117	tel	tel	PROPN
admet-497	1	118	.	.	PUNCT
admet-497	1	119	:	:	PUNCT
admet-497	2	1	+34	+34	ADJ
admet-497	2	2	934021284	934021284	NUM
admet-497	2	3	;	;	PUNCT
admet-497	2	4	fax	fax	NOUN
admet-497	2	5	:	:	PUNCT
admet-497	2	6	+34	+34	ADJ
admet-497	2	7	934021233	934021233	NUM
admet-497	2	8	received	receive	VERB
admet-497	2	9	:	:	PUNCT
admet-497	2	10	january	january	PROPN
admet-497	2	11	12	12	NUM
admet-497	2	12	,	,	PUNCT
admet-497	2	13	2018	2018	NUM
admet-497	2	14	;	;	PUNCT
admet-497	2	15	revised	revise	VERB
admet-497	2	16	:	:	PUNCT
admet-497	2	17	march	march	PROPN
admet-497	2	18	16	16	NUM
admet-497	2	19	,	,	PUNCT
admet-497	2	20	2018	2018	NUM
admet-497	2	21	;	;	PUNCT
admet-497	2	22	published	publish	VERB
admet-497	2	23	:	:	PUNCT
admet-497	2	24	march	march	PROPN
admet-497	2	25	25	25	NUM
admet-497	2	26	,	,	PUNCT
admet-497	2	27	2018	2018	NUM
admet-497	2	28	abstract	abstract	NOUN
admet-497	2	29	the	the	DET
admet-497	2	30	synthesis	synthesis	NOUN
admet-497	2	31	of	of	ADP
admet-497	2	32	cocrystals	cocrystal	NOUN
admet-497	2	33	is	be	AUX
admet-497	2	34	presented	present	VERB
admet-497	2	35	as	as	ADP
admet-497	2	36	an	an	DET
admet-497	2	37	alternative	alternative	NOUN
admet-497	2	38	to	to	PART
admet-497	2	39	improve	improve	VERB
admet-497	2	40	the	the	DET
admet-497	2	41	properties	property	NOUN
admet-497	2	42	of	of	ADP
admet-497	2	43	active	active	ADJ
admet-497	2	44	pharmaceutical	pharmaceutical	ADJ
admet-497	2	45	ingredients	ingredient	NOUN
admet-497	2	46	,	,	PUNCT
admet-497	2	47	especially	especially	ADV
admet-497	2	48	those	those	PRON
admet-497	2	49	related	relate	VERB
admet-497	2	50	to	to	ADP
admet-497	2	51	solubility	solubility	NOUN
admet-497	2	52	and	and	CCONJ
admet-497	2	53	dissolution	dissolution	NOUN
admet-497	2	54	rate	rate	NOUN
admet-497	2	55	.	.	PUNCT
admet-497	3	1	in	in	ADP
admet-497	3	2	this	this	DET
admet-497	3	3	work	work	NOUN
admet-497	3	4	the	the	DET
admet-497	3	5	dissolution	dissolution	NOUN
admet-497	3	6	rate	rate	NOUN
admet-497	3	7	of	of	ADP
admet-497	3	8	ciprofloxacin	ciprofloxacin	NOUN
admet-497	3	9	,	,	PUNCT
admet-497	3	10	a	a	DET
admet-497	3	11	zwitterionic	zwitterionic	ADJ
admet-497	3	12	fluoroquinolone	fluoroquinolone	NOUN
admet-497	3	13	antibiotic	antibiotic	ADJ
admet-497	3	14	,	,	PUNCT
admet-497	3	15	has	have	AUX
admet-497	3	16	been	be	AUX
admet-497	3	17	compared	compare	VERB
admet-497	3	18	to	to	ADP
admet-497	3	19	its	its	PRON
admet-497	3	20	cocrystal	cocrystal	NOUN
admet-497	3	21	with	with	ADP
admet-497	3	22	resorcinol	resorcinol	NOUN
admet-497	3	23	.	.	PUNCT
admet-497	4	1	to	to	ADP
admet-497	4	2	this	this	DET
admet-497	4	3	end	end	NOUN
admet-497	4	4	,	,	PUNCT
admet-497	4	5	dissolution	dissolution	ADJ
admet-497	4	6	rate	rate	NOUN
admet-497	4	7	has	have	AUX
admet-497	4	8	been	be	AUX
admet-497	4	9	determined	determine	VERB
admet-497	4	10	at	at	ADP
admet-497	4	11	several	several	ADJ
admet-497	4	12	biorelevant	biorelevant	ADJ
admet-497	4	13	ph	ph	ADJ
admet-497	4	14	values	value	NOUN
admet-497	4	15	,	,	PUNCT
admet-497	4	16	and	and	CCONJ
admet-497	4	17	also	also	ADV
admet-497	4	18	in	in	ADP
admet-497	4	19	two	two	NUM
admet-497	4	20	simulated	simulate	VERB
admet-497	4	21	gastrointestinal	gastrointestinal	ADJ
admet-497	4	22	fluids	fluid	NOUN
admet-497	4	23	(	(	PUNCT
admet-497	4	24	fessif	fessif	NOUN
admet-497	4	25	and	and	CCONJ
admet-497	4	26	fassif	fassif	NOUN
admet-497	4	27	)	)	PUNCT
admet-497	4	28	.	.	PUNCT
admet-497	5	1	results	result	NOUN
admet-497	5	2	show	show	VERB
admet-497	5	3	that	that	SCONJ
admet-497	5	4	both	both	ADV
admet-497	5	5	,	,	PUNCT
admet-497	5	6	ciprofloxacin	ciprofloxacin	PROPN
admet-497	5	7	and	and	CCONJ
admet-497	5	8	the	the	DET
admet-497	5	9	cocrystal	cocrystal	PROPN
admet-497	5	10	,	,	PUNCT
admet-497	5	11	dissolve	dissolve	VERB
admet-497	5	12	more	more	ADV
admet-497	5	13	slowly	slowly	ADV
admet-497	5	14	as	as	ADP
admet-497	5	15	ph	ph	ADJ
admet-497	5	16	increases	increase	NOUN
admet-497	5	17	(	(	PUNCT
admet-497	5	18	from	from	ADP
admet-497	5	19	2.0	2.0	NUM
admet-497	5	20	to	to	ADP
admet-497	5	21	7.4	7.4	NUM
admet-497	5	22	)	)	PUNCT
admet-497	5	23	,	,	PUNCT
admet-497	5	24	as	as	ADP
admet-497	5	25	ionization	ionization	NOUN
admet-497	5	26	degree	degree	NOUN
admet-497	5	27	of	of	ADP
admet-497	5	28	ciprofloxacin	ciprofloxacin	NOUN
admet-497	5	29	decreases	decrease	VERB
admet-497	5	30	.	.	PUNCT
admet-497	6	1	in	in	ADP
admet-497	6	2	addition	addition	NOUN
admet-497	6	3	,	,	PUNCT
admet-497	6	4	dissolution	dissolution	NOUN
admet-497	6	5	is	be	AUX
admet-497	6	6	not	not	PART
admet-497	6	7	enhanced	enhance	VERB
admet-497	6	8	by	by	ADP
admet-497	6	9	the	the	DET
admet-497	6	10	components	component	NOUN
admet-497	6	11	of	of	ADP
admet-497	6	12	the	the	DET
admet-497	6	13	gastrointestinal	gastrointestinal	ADJ
admet-497	6	14	fluids	fluid	NOUN
admet-497	6	15	.	.	PUNCT
admet-497	7	1	keywords	keyword	VERB
admet-497	7	2	dissolution	dissolution	NOUN
admet-497	7	3	rate	rate	NOUN
admet-497	7	4	;	;	PUNCT
admet-497	7	5	cocrystal	cocrystal	PROPN
admet-497	7	6	;	;	PUNCT
admet-497	7	7	ciprofloxacin	ciprofloxacin	PROPN
admet-497	7	8	;	;	PUNCT
admet-497	7	9	solid	solid	ADJ
admet-497	7	10	state	state	NOUN
admet-497	7	11	;	;	PUNCT
admet-497	7	12	fassif	fassif	NOUN
admet-497	7	13	;	;	PUNCT
admet-497	7	14	fessif	fessif	NOUN
admet-497	7	15	;	;	PUNCT
admet-497	7	16	simulated	simulate	VERB
admet-497	7	17	gastrointestinal	gastrointestinal	ADJ
admet-497	7	18	fluid	fluid	NOUN
admet-497	7	19	introduction	introduction	NOUN
admet-497	7	20	the	the	DET
admet-497	7	21	dissolution	dissolution	NOUN
admet-497	7	22	rate	rate	NOUN
admet-497	7	23	plays	play	VERB
admet-497	7	24	an	an	DET
admet-497	7	25	important	important	ADJ
admet-497	7	26	role	role	NOUN
admet-497	7	27	in	in	ADP
admet-497	7	28	drugs	drug	NOUN
admet-497	7	29	with	with	ADP
admet-497	7	30	limited	limited	ADJ
admet-497	7	31	solubility	solubility	NOUN
admet-497	7	32	.	.	PUNCT
admet-497	8	1	in	in	ADP
admet-497	8	2	fact	fact	NOUN
admet-497	8	3	,	,	PUNCT
admet-497	8	4	for	for	ADP
admet-497	8	5	drugs	drug	NOUN
admet-497	8	6	with	with	ADP
admet-497	8	7	very	very	ADV
admet-497	8	8	poor	poor	ADJ
admet-497	8	9	aqueous	aqueous	ADJ
admet-497	8	10	solubility	solubility	NOUN
admet-497	8	11	,	,	PUNCT
admet-497	8	12	the	the	DET
admet-497	8	13	rate	rate	NOUN
admet-497	8	14	at	at	ADP
admet-497	8	15	which	which	PRON
admet-497	8	16	they	they	PRON
admet-497	8	17	dissolve	dissolve	VERB
admet-497	8	18	is	be	AUX
admet-497	8	19	often	often	ADV
admet-497	8	20	the	the	DET
admet-497	8	21	slowest	slow	ADJ
admet-497	8	22	step	step	NOUN
admet-497	8	23	,	,	PUNCT
admet-497	8	24	and	and	CCONJ
admet-497	8	25	it	it	PRON
admet-497	8	26	exerts	exert	VERB
admet-497	8	27	a	a	DET
admet-497	8	28	ratelimiting	ratelimiting	NOUN
admet-497	8	29	effect	effect	NOUN
admet-497	8	30	on	on	ADP
admet-497	8	31	drug	drug	NOUN
admet-497	8	32	bioavailability	bioavailability	NOUN
admet-497	8	33	.	.	PUNCT
admet-497	9	1	currently	currently	ADV
admet-497	9	2	about	about	ADV
admet-497	9	3	60	60	NUM
admet-497	9	4	%	%	NOUN
admet-497	9	5	of	of	ADP
admet-497	9	6	the	the	DET
admet-497	9	7	drugs	drug	NOUN
admet-497	9	8	coming	come	VERB
admet-497	9	9	from	from	ADP
admet-497	9	10	synthesis	synthesis	NOUN
admet-497	9	11	are	be	AUX
admet-497	9	12	poorly	poorly	ADV
admet-497	9	13	soluble	soluble	ADJ
admet-497	9	14	and	and	CCONJ
admet-497	9	15	hence	hence	ADV
admet-497	9	16	have	have	VERB
admet-497	9	17	a	a	DET
admet-497	9	18	low	low	ADJ
admet-497	9	19	oral	oral	ADJ
admet-497	9	20	bioavailability	bioavailability	NOUN
admet-497	10	1	[	[	X
admet-497	10	2	1	1	NUM
admet-497	10	3	]	]	PUNCT
admet-497	10	4	.	.	PUNCT
admet-497	11	1	diverse	diverse	ADJ
admet-497	11	2	strategies	strategy	NOUN
admet-497	11	3	have	have	AUX
admet-497	11	4	been	be	AUX
admet-497	11	5	developed	develop	VERB
admet-497	11	6	to	to	PART
admet-497	11	7	improve	improve	VERB
admet-497	11	8	solubility	solubility	NOUN
admet-497	11	9	,	,	PUNCT
admet-497	11	10	dissolution	dissolution	NOUN
admet-497	11	11	rate	rate	NOUN
admet-497	11	12	and	and	CCONJ
admet-497	11	13	subsequently	subsequently	ADV
admet-497	11	14	the	the	DET
admet-497	11	15	bioavailability	bioavailability	NOUN
admet-497	11	16	of	of	ADP
admet-497	11	17	these	these	DET
admet-497	11	18	drugs	drug	NOUN
admet-497	11	19	.	.	PUNCT
admet-497	12	1	these	these	PRON
admet-497	12	2	include	include	VERB
admet-497	12	3	formation	formation	NOUN
admet-497	12	4	of	of	ADP
admet-497	12	5	salts	salt	NOUN
admet-497	12	6	,	,	PUNCT
admet-497	12	7	inclusion	inclusion	NOUN
admet-497	12	8	complexes	complex	NOUN
admet-497	12	9	with	with	ADP
admet-497	12	10	cyclodextrines	cyclodextrine	NOUN
admet-497	12	11	,	,	PUNCT
admet-497	12	12	amorphization	amorphization	NOUN
admet-497	12	13	,	,	PUNCT
admet-497	12	14	formulation	formulation	NOUN
admet-497	12	15	of	of	ADP
admet-497	12	16	solid	solid	ADJ
admet-497	12	17	dispersions	dispersion	NOUN
admet-497	12	18	with	with	ADP
admet-497	12	19	hydrophilic	hydrophilic	ADJ
admet-497	12	20	polymers	polymer	NOUN
admet-497	12	21	,	,	PUNCT
admet-497	12	22	changing	change	VERB
admet-497	12	23	the	the	DET
admet-497	12	24	crystal	crystal	NOUN
admet-497	12	25	form	form	NOUN
admet-497	12	26	(	(	PUNCT
admet-497	12	27	polymorphs	polymorphs	NOUN
admet-497	12	28	,	,	PUNCT
admet-497	12	29	hydrates	hydrate	NOUN
admet-497	12	30	,	,	PUNCT
admet-497	12	31	etc	etc	X
admet-497	12	32	.	.	X
admet-497	12	33	)	)	PUNCT
admet-497	13	1	[	[	X
admet-497	13	2	2	2	NUM
admet-497	13	3	-	-	SYM
admet-497	13	4	5	5	NUM
admet-497	13	5	]	]	PUNCT
admet-497	13	6	.	.	PUNCT
admet-497	14	1	a	a	DET
admet-497	14	2	promising	promising	ADJ
admet-497	14	3	strategy	strategy	NOUN
admet-497	14	4	is	be	AUX
admet-497	14	5	the	the	DET
admet-497	14	6	crystallisation	crystallisation	NOUN
admet-497	14	7	of	of	ADP
admet-497	14	8	the	the	DET
admet-497	14	9	drug	drug	NOUN
admet-497	14	10	with	with	ADP
admet-497	14	11	a	a	DET
admet-497	14	12	suitable	suitable	ADJ
admet-497	14	13	coformer	coformer	NOUN
admet-497	14	14	to	to	PART
admet-497	14	15	obtain	obtain	VERB
admet-497	14	16	a	a	DET
admet-497	14	17	cocrystal	cocrystal	NOUN
admet-497	14	18	,	,	PUNCT
admet-497	14	19	which	which	PRON
admet-497	14	20	may	may	AUX
admet-497	14	21	have	have	VERB
admet-497	14	22	different	different	ADJ
admet-497	14	23	physical	physical	ADJ
admet-497	14	24	properties	property	NOUN
admet-497	14	25	compared	compare	VERB
admet-497	14	26	to	to	ADP
admet-497	14	27	the	the	DET
admet-497	14	28	drug	drug	NOUN
admet-497	14	29	,	,	PUNCT
admet-497	14	30	such	such	ADJ
admet-497	14	31	as	as	ADP
admet-497	14	32	melting	melting	NOUN
admet-497	14	33	point	point	NOUN
admet-497	14	34	,	,	PUNCT
admet-497	14	35	moisture	moisture	NOUN
admet-497	14	36	sorption	sorption	NOUN
admet-497	14	37	,	,	PUNCT
admet-497	14	38	compressibility	compressibility	NOUN
admet-497	14	39	,	,	PUNCT
admet-497	14	40	solubility	solubility	NOUN
admet-497	14	41	,	,	PUNCT
admet-497	14	42	and	and	CCONJ
admet-497	14	43	dissolution	dissolution	NOUN
admet-497	14	44	rate	rate	NOUN
admet-497	14	45	,	,	PUNCT
admet-497	14	46	without	without	ADP
admet-497	14	47	altering	alter	VERB
admet-497	14	48	the	the	DET
admet-497	14	49	pharmacological	pharmacological	ADJ
admet-497	14	50	effect	effect	NOUN
admet-497	14	51	of	of	ADP
admet-497	14	52	the	the	DET
admet-497	14	53	drug	drug	NOUN
admet-497	14	54	candidate	candidate	NOUN
admet-497	14	55	[	[	X
admet-497	14	56	4	4	NUM
admet-497	14	57	-	-	SYM
admet-497	14	58	7	7	NUM
admet-497	14	59	]	]	PUNCT
admet-497	14	60	.	.	PUNCT
admet-497	15	1	a	a	DET
admet-497	15	2	cocrystal	cocrystal	NOUN
admet-497	15	3	can	can	AUX
admet-497	15	4	be	be	AUX
admet-497	15	5	defined	define	VERB
admet-497	15	6	as	as	ADP
admet-497	15	7	a	a	DET
admet-497	15	8	stoichiometric	stoichiometric	ADJ
admet-497	15	9	multi	multi	ADJ
admet-497	15	10	-	-	ADJ
admet-497	15	11	component	component	ADJ
admet-497	15	12	system	system	NOUN
admet-497	15	13	connected	connect	VERB
admet-497	15	14	by	by	ADP
admet-497	15	15	non	non	ADJ
admet-497	15	16	-	-	ADJ
admet-497	15	17	covalent	covalent	ADJ
admet-497	15	18	interactions	interaction	NOUN
admet-497	15	19	where	where	SCONJ
admet-497	15	20	all	all	DET
admet-497	15	21	the	the	DET
admet-497	15	22	components	component	NOUN
admet-497	15	23	present	present	ADJ
admet-497	15	24	are	be	AUX
admet-497	15	25	solid	solid	ADJ
admet-497	15	26	under	under	ADP
admet-497	15	27	ambient	ambient	ADJ
admet-497	15	28	conditions	condition	NOUN
admet-497	15	29	[	[	X
admet-497	15	30	5	5	NUM
admet-497	15	31	]	]	PUNCT
admet-497	15	32	.	.	PUNCT
admet-497	16	1	a	a	DET
admet-497	16	2	pharmaceutical	pharmaceutical	ADJ
admet-497	16	3	cocrystal	cocrystal	NOUN
admet-497	16	4	is	be	AUX
admet-497	16	5	composed	compose	VERB
admet-497	16	6	of	of	ADP
admet-497	16	7	an	an	DET
admet-497	16	8	active	active	ADJ
admet-497	16	9	pharmaceutical	pharmaceutical	ADJ
admet-497	16	10	ingredient	ingredient	NOUN
admet-497	16	11	(	(	PUNCT
admet-497	16	12	api	api	NOUN
admet-497	16	13	)	)	PUNCT
admet-497	16	14	and	and	CCONJ
admet-497	16	15	a	a	DET
admet-497	16	16	suitable	suitable	ADJ
admet-497	16	17	and	and	CCONJ
admet-497	16	18	pharmaceutically	pharmaceutically	PROPN
admet-497	16	19	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-497	16	20	c.	c.	PROPN
admet-497	16	21	ràfols	ràfol	VERB
admet-497	16	22	et	et	PROPN
admet-497	16	23	al	al	PROPN
admet-497	16	24	.	.	PROPN
admet-497	16	25	admet	admet	PROPN
admet-497	16	26	&	&	CCONJ
admet-497	16	27	dmpk	dmpk	PROPN
admet-497	16	28	6(1	6(1	NUM
admet-497	16	29	)	)	PUNCT
admet-497	16	30	(	(	PUNCT
admet-497	16	31	2018	2018	NUM
admet-497	16	32	)	)	PUNCT
admet-497	16	33	61	61	NUM
admet-497	16	34	-	-	SYM
admet-497	16	35	70	70	NUM
admet-497	16	36	62	62	NUM
admet-497	16	37	accepted	accept	VERB
admet-497	16	38	molecule	molecule	NOUN
admet-497	16	39	called	call	VERB
admet-497	16	40	a	a	DET
admet-497	16	41	coformer	coformer	NOUN
admet-497	16	42	.	.	PUNCT
admet-497	17	1	cocrystals	cocrystal	NOUN
admet-497	17	2	are	be	AUX
admet-497	17	3	constructed	construct	VERB
admet-497	17	4	from	from	ADP
admet-497	17	5	intermolecular	intermolecular	ADJ
admet-497	17	6	interactions	interaction	NOUN
admet-497	17	7	such	such	ADJ
admet-497	17	8	as	as	ADP
admet-497	17	9	van	van	PROPN
admet-497	17	10	der	der	NOUN
admet-497	17	11	waals	waal	NOUN
admet-497	17	12	contact	contact	NOUN
admet-497	17	13	forces	force	NOUN
admet-497	17	14	,	,	PUNCT
admet-497	17	15	π	π	PROPN
admet-497	17	16	-	-	PUNCT
admet-497	17	17	π	π	NOUN
admet-497	17	18	interactions	interaction	NOUN
admet-497	17	19	,	,	PUNCT
admet-497	17	20	and	and	CCONJ
admet-497	17	21	especially	especially	ADV
admet-497	17	22	hydrogen	hydrogen	NOUN
admet-497	17	23	bonding	bonding	NOUN
admet-497	17	24	.	.	PUNCT
admet-497	18	1	there	there	PRON
admet-497	18	2	are	be	VERB
admet-497	18	3	several	several	ADJ
admet-497	18	4	methods	method	NOUN
admet-497	18	5	to	to	PART
admet-497	18	6	obtain	obtain	VERB
admet-497	18	7	cocrystals	cocrystal	NOUN
admet-497	18	8	in	in	ADP
admet-497	18	9	the	the	DET
admet-497	18	10	literature	literature	NOUN
admet-497	18	11	,	,	PUNCT
admet-497	18	12	such	such	ADJ
admet-497	18	13	as	as	ADP
admet-497	18	14	slow	slow	ADJ
admet-497	18	15	solvent	solvent	NOUN
admet-497	18	16	evaporation	evaporation	NOUN
admet-497	18	17	,	,	PUNCT
admet-497	18	18	slurry	slurry	NOUN
admet-497	18	19	crystallization	crystallization	NOUN
admet-497	18	20	,	,	PUNCT
admet-497	18	21	solid	solid	ADJ
admet-497	18	22	state	state	NOUN
admet-497	18	23	grinding	grinding	NOUN
admet-497	18	24	,	,	PUNCT
admet-497	18	25	and	and	CCONJ
admet-497	18	26	melting	melt	VERB
admet-497	18	27	[	[	X
admet-497	18	28	8	8	NUM
admet-497	18	29	-	-	SYM
admet-497	18	30	13	13	NUM
admet-497	18	31	]	]	PUNCT
admet-497	18	32	.	.	PUNCT
admet-497	19	1	the	the	DET
admet-497	19	2	api	api	NOUN
admet-497	19	3	selected	select	VERB
admet-497	19	4	in	in	ADP
admet-497	19	5	this	this	DET
admet-497	19	6	study	study	NOUN
admet-497	19	7	is	be	AUX
admet-497	19	8	ciprofloxacin	ciprofloxacin	NOUN
admet-497	19	9	(	(	PUNCT
admet-497	19	10	cip	cip	NOUN
admet-497	19	11	)	)	PUNCT
admet-497	19	12	,	,	PUNCT
admet-497	19	13	a	a	DET
admet-497	19	14	poorly	poorly	ADV
admet-497	19	15	soluble	soluble	ADJ
admet-497	19	16	fluoroquinolone	fluoroquinolone	NOUN
admet-497	19	17	antibiotic	antibiotic	ADJ
admet-497	19	18	active	active	ADJ
admet-497	19	19	against	against	ADP
admet-497	19	20	both	both	DET
admet-497	19	21	gram	gram	NOUN
admet-497	19	22	-	-	PUNCT
admet-497	19	23	positive	positive	ADJ
admet-497	19	24	and	and	CCONJ
admet-497	19	25	gram	gram	NOUN
admet-497	19	26	-	-	PUNCT
admet-497	19	27	negative	negative	ADJ
admet-497	19	28	bacteria	bacteria	NOUN
admet-497	19	29	,	,	PUNCT
admet-497	19	30	which	which	PRON
admet-497	19	31	is	be	AUX
admet-497	19	32	mainly	mainly	ADV
admet-497	19	33	used	use	VERB
admet-497	19	34	in	in	ADP
admet-497	19	35	the	the	DET
admet-497	19	36	treatment	treatment	NOUN
admet-497	19	37	of	of	ADP
admet-497	19	38	lower	low	ADJ
admet-497	19	39	respiratory	respiratory	ADJ
admet-497	19	40	and	and	CCONJ
admet-497	19	41	urinary	urinary	ADJ
admet-497	19	42	tract	tract	NOUN
admet-497	19	43	infections	infection	NOUN
admet-497	19	44	.	.	PUNCT
admet-497	20	1	the	the	DET
admet-497	20	2	aim	aim	NOUN
admet-497	20	3	of	of	ADP
admet-497	20	4	this	this	DET
admet-497	20	5	study	study	NOUN
admet-497	20	6	is	be	AUX
admet-497	20	7	to	to	PART
admet-497	20	8	compare	compare	VERB
admet-497	20	9	the	the	DET
admet-497	20	10	dissolution	dissolution	NOUN
admet-497	20	11	rate	rate	NOUN
admet-497	20	12	of	of	ADP
admet-497	20	13	cip	cip	NOUN
admet-497	20	14	in	in	ADP
admet-497	20	15	different	different	ADJ
admet-497	20	16	media	medium	NOUN
admet-497	20	17	and	and	CCONJ
admet-497	20	18	ph	ph	ADJ
admet-497	20	19	values	value	NOUN
admet-497	20	20	to	to	ADP
admet-497	20	21	that	that	PRON
admet-497	20	22	of	of	ADP
admet-497	20	23	the	the	DET
admet-497	20	24	prepared	prepare	VERB
admet-497	20	25	cocrystal	cocrystal	NOUN
admet-497	20	26	with	with	ADP
admet-497	20	27	resorcinol	resorcinol	NOUN
admet-497	20	28	.	.	PUNCT
admet-497	21	1	in	in	ADP
admet-497	21	2	addition	addition	NOUN
admet-497	21	3	,	,	PUNCT
admet-497	21	4	possible	possible	ADJ
admet-497	21	5	changes	change	NOUN
admet-497	21	6	in	in	ADP
admet-497	21	7	the	the	DET
admet-497	21	8	solid	solid	ADJ
admet-497	21	9	state	state	NOUN
admet-497	21	10	of	of	ADP
admet-497	21	11	the	the	DET
admet-497	21	12	drug	drug	NOUN
admet-497	21	13	and	and	CCONJ
admet-497	21	14	its	its	PRON
admet-497	21	15	cocrystal	cocrystal	NOUN
admet-497	21	16	during	during	ADP
admet-497	21	17	the	the	DET
admet-497	21	18	dissolution	dissolution	NOUN
admet-497	21	19	process	process	NOUN
admet-497	21	20	are	be	AUX
admet-497	21	21	also	also	ADV
admet-497	21	22	investigated	investigate	VERB
admet-497	21	23	.	.	PUNCT
admet-497	22	1	materials	material	NOUN
admet-497	22	2	and	and	CCONJ
admet-497	22	3	methods	method	NOUN
admet-497	22	4	instruments	instrument	VERB
admet-497	22	5	dissolution	dissolution	NOUN
admet-497	22	6	rate	rate	NOUN
admet-497	22	7	assays	assay	NOUN
admet-497	22	8	were	be	AUX
admet-497	22	9	carried	carry	VERB
admet-497	22	10	out	out	ADP
admet-497	22	11	using	use	VERB
admet-497	22	12	a	a	DET
admet-497	22	13	glpka	glpka	NOUN
admet-497	22	14	titrator	titrator	NOUN
admet-497	22	15	from	from	ADP
admet-497	22	16	sirius	sirius	PROPN
admet-497	22	17	analytical	analytical	PROPN
admet-497	22	18	instruments	instruments	PROPN
admet-497	22	19	ltd	ltd	PROPN
admet-497	22	20	(	(	PUNCT
admet-497	22	21	forest	forest	NOUN
admet-497	22	22	row	row	NOUN
admet-497	22	23	,	,	PUNCT
admet-497	22	24	uk	uk	PROPN
admet-497	22	25	)	)	PUNCT
admet-497	22	26	,	,	PUNCT
admet-497	22	27	equipped	equip	VERB
admet-497	22	28	with	with	ADP
admet-497	22	29	a	a	DET
admet-497	22	30	sirius	sirius	PROPN
admet-497	22	31	d	d	PROPN
admet-497	22	32	-	-	PUNCT
admet-497	22	33	pas	pas	ADJ
admet-497	22	34	spectrometer	spectrometer	NOUN
admet-497	22	35	,	,	PUNCT
admet-497	22	36	a	a	DET
admet-497	22	37	bifurcated	bifurcated	ADJ
admet-497	22	38	fibre	fibre	NOUN
admet-497	22	39	-	-	PUNCT
admet-497	22	40	optic	optic	NOUN
admet-497	22	41	dip	dip	NOUN
admet-497	22	42	probe	probe	NOUN
admet-497	22	43	from	from	ADP
admet-497	22	44	hellma	hellma	NOUN
admet-497	22	45	analytics	analytic	NOUN
admet-497	22	46	(	(	PUNCT
admet-497	22	47	müllheim	müllheim	PROPN
admet-497	22	48	,	,	PUNCT
admet-497	22	49	germany	germany	PROPN
admet-497	22	50	)	)	PUNCT
admet-497	22	51	with	with	ADP
admet-497	22	52	path	path	NOUN
admet-497	22	53	length	length	NOUN
admet-497	22	54	of	of	ADP
admet-497	22	55	1	1	NUM
admet-497	22	56	cm	cm	NOUN
admet-497	22	57	,	,	PUNCT
admet-497	22	58	and	and	CCONJ
admet-497	22	59	a	a	DET
admet-497	22	60	two	two	NUM
admet-497	22	61	channels	channel	NOUN
admet-497	22	62	solvent	solvent	NOUN
admet-497	22	63	degasser	degasser	PROPN
admet-497	22	64	from	from	ADP
admet-497	22	65	smi	smi	PROPN
admet-497	22	66	-	-	PUNCT
admet-497	22	67	labhut	labhut	PROPN
admet-497	22	68	ltd	ltd	PROPN
admet-497	22	69	.	.	PUNCT
admet-497	23	1	(	(	PUNCT
admet-497	23	2	churcham	churcham	PROPN
admet-497	23	3	,	,	PUNCT
admet-497	23	4	uk	uk	PROPN
admet-497	23	5	)	)	PUNCT
admet-497	23	6	.	.	PUNCT
admet-497	24	1	the	the	DET
admet-497	24	2	apparatus	apparatus	NOUN
admet-497	24	3	was	be	AUX
admet-497	24	4	controlled	control	VERB
admet-497	24	5	from	from	ADP
admet-497	24	6	a	a	DET
admet-497	24	7	computer	computer	NOUN
admet-497	24	8	running	run	VERB
admet-497	24	9	the	the	DET
admet-497	24	10	refinementpro2	refinementpro2	PROPN
admet-497	24	11	software	software	NOUN
admet-497	24	12	.	.	PUNCT
admet-497	25	1	acidity	acidity	NOUN
admet-497	25	2	constant	constant	ADJ
admet-497	25	3	determinations	determination	NOUN
admet-497	25	4	were	be	AUX
admet-497	25	5	done	do	VERB
admet-497	25	6	with	with	ADP
admet-497	25	7	the	the	DET
admet-497	25	8	same	same	ADJ
admet-497	25	9	instrument	instrument	NOUN
admet-497	25	10	as	as	SCONJ
admet-497	25	11	described	describe	VERB
admet-497	25	12	elsewhere	elsewhere	ADV
admet-497	25	13	[	[	X
admet-497	25	14	14	14	NUM
admet-497	25	15	]	]	PUNCT
admet-497	25	16	.	.	PUNCT
admet-497	26	1	the	the	DET
admet-497	26	2	powder	powder	NOUN
admet-497	26	3	x	x	NOUN
admet-497	26	4	-	-	NOUN
admet-497	26	5	ray	ray	NOUN
admet-497	26	6	diffraction	diffraction	NOUN
admet-497	26	7	(	(	PUNCT
admet-497	26	8	pxrd	pxrd	NOUN
admet-497	26	9	)	)	PUNCT
admet-497	26	10	characterization	characterization	NOUN
admet-497	26	11	was	be	AUX
admet-497	26	12	performed	perform	VERB
admet-497	26	13	using	use	VERB
admet-497	26	14	a	a	DET
admet-497	26	15	panalytical	panalytical	ADJ
admet-497	26	16	x’pert	x’pert	PROPN
admet-497	26	17	pro	pro	X
admet-497	26	18	mpd	mpd	PROPN
admet-497	26	19	/	/	ADP
admet-497	26	20	powder	powder	NOUN
admet-497	26	21	diffractometer	diffractometer	NOUN
admet-497	26	22	of	of	ADP
admet-497	26	23	240	240	NUM
admet-497	26	24	mm	mm	NOUN
admet-497	26	25	radius	radius	NOUN
admet-497	26	26	equipped	equip	VERB
admet-497	26	27	with	with	ADP
admet-497	26	28	a	a	DET
admet-497	26	29	pixcel	pixcel	ADJ
admet-497	26	30	detector	detector	NOUN
admet-497	26	31	from	from	ADP
admet-497	26	32	panalytical	panalytical	ADJ
admet-497	26	33	b.v	b.v	PROPN
admet-497	26	34	.	.	PUNCT
admet-497	27	1	(	(	PUNCT
admet-497	27	2	almelo	almelo	NOUN
admet-497	27	3	,	,	PUNCT
admet-497	27	4	the	the	DET
admet-497	27	5	netherlands	netherlands	PROPN
admet-497	27	6	)	)	PUNCT
admet-497	27	7	.	.	PUNCT
admet-497	28	1	the	the	DET
admet-497	28	2	apparatus	apparatus	NOUN
admet-497	28	3	was	be	AUX
admet-497	28	4	set	set	VERB
admet-497	28	5	in	in	ADP
admet-497	28	6	a	a	DET
admet-497	28	7	configuration	configuration	NOUN
admet-497	28	8	of	of	ADP
admet-497	28	9	convergent	convergent	NOUN
admet-497	28	10	beam	beam	NOUN
admet-497	28	11	with	with	ADP
admet-497	28	12	a	a	DET
admet-497	28	13	focalizing	focalizing	NOUN
admet-497	28	14	mirror	mirror	NOUN
admet-497	28	15	and	and	CCONJ
admet-497	28	16	a	a	DET
admet-497	28	17	transmission	transmission	NOUN
admet-497	28	18	geometry	geometry	NOUN
admet-497	28	19	,	,	PUNCT
admet-497	28	20	with	with	ADP
admet-497	28	21	flat	flat	ADJ
admet-497	28	22	samples	sample	NOUN
admet-497	28	23	sandwiched	sandwich	VERB
admet-497	28	24	between	between	ADP
admet-497	28	25	low	low	ADJ
admet-497	28	26	absorbing	absorbing	ADJ
admet-497	28	27	films	film	NOUN
admet-497	28	28	.	.	PUNCT
admet-497	29	1	the	the	DET
admet-497	29	2	detector	detector	NOUN
admet-497	29	3	active	active	ADJ
admet-497	29	4	length	length	NOUN
admet-497	29	5	was	be	AUX
admet-497	29	6	3.347º.	3.347º.	NUM
admet-497	29	7	work	work	NOUN
admet-497	29	8	power	power	NOUN
admet-497	29	9	was	be	AUX
admet-497	29	10	45	45	NUM
admet-497	29	11	kv	kv	PROPN
admet-497	29	12	–	–	PUNCT
admet-497	29	13	40	40	NUM
admet-497	29	14	ma	ma	NOUN
admet-497	29	15	with	with	ADP
admet-497	29	16	a	a	DET
admet-497	29	17	defined	define	VERB
admet-497	29	18	beam	beam	NOUN
admet-497	29	19	height	height	NOUN
admet-497	29	20	of	of	ADP
admet-497	29	21	0.4	0.4	NUM
admet-497	29	22	mm	mm	NOUN
admet-497	29	23	.	.	PROPN
admet-497	30	1	five	five	NUM
admet-497	30	2	repeated	repeat	VERB
admet-497	30	3	scans	scan	NOUN
admet-497	30	4	were	be	AUX
admet-497	30	5	done	do	VERB
admet-497	30	6	from	from	ADP
admet-497	30	7	2	2	NUM
admet-497	30	8	to	to	ADP
admet-497	30	9	60	60	NUM
admet-497	30	10	2º	2º	NUM
admet-497	30	11	with	with	ADP
admet-497	30	12	a	a	DET
admet-497	30	13	step	step	NOUN
admet-497	30	14	size	size	NOUN
admet-497	30	15	of	of	ADP
admet-497	30	16	0.026	0.026	NUM
admet-497	30	17	2º	2º	NUM
admet-497	30	18	and	and	CCONJ
admet-497	30	19	a	a	DET
admet-497	30	20	measuring	measure	VERB
admet-497	30	21	time	time	NOUN
admet-497	30	22	of	of	ADP
admet-497	30	23	40	40	NUM
admet-497	30	24	seconds	second	NOUN
admet-497	30	25	per	per	ADP
admet-497	30	26	step	step	NOUN
admet-497	30	27	.	.	PUNCT
admet-497	31	1	calorimetric	calorimetric	ADJ
admet-497	31	2	analysis	analysis	NOUN
admet-497	31	3	of	of	ADP
admet-497	31	4	the	the	DET
admet-497	31	5	samples	sample	NOUN
admet-497	31	6	was	be	AUX
admet-497	31	7	performed	perform	VERB
admet-497	31	8	on	on	ADP
admet-497	31	9	differential	differential	ADJ
admet-497	31	10	scanning	scanning	NOUN
admet-497	31	11	calorimetry	calorimetry	NOUN
admet-497	31	12	(	(	PUNCT
admet-497	31	13	dsc	dsc	NOUN
admet-497	31	14	)	)	PUNCT
admet-497	31	15	(	(	PUNCT
admet-497	31	16	mettler	mettler	PROPN
admet-497	31	17	toledo	toledo	PROPN
admet-497	31	18	dsc822e	dsc822e	PROPN
admet-497	31	19	,	,	PUNCT
admet-497	31	20	switzerland	switzerland	PROPN
admet-497	31	21	)	)	PUNCT
admet-497	31	22	.	.	PUNCT
admet-497	32	1	samples	sample	NOUN
admet-497	32	2	equivalent	equivalent	ADJ
admet-497	32	3	to	to	ADP
admet-497	32	4	2	2	NUM
admet-497	32	5	-	-	SYM
admet-497	32	6	5	5	NUM
admet-497	32	7	mg	mg	NOUN
admet-497	32	8	of	of	ADP
admet-497	32	9	the	the	DET
admet-497	32	10	drug	drug	NOUN
admet-497	32	11	or	or	CCONJ
admet-497	32	12	cocrystal	cocrystal	ADJ
admet-497	32	13	were	be	AUX
admet-497	32	14	loaded	load	VERB
admet-497	32	15	into	into	ADP
admet-497	32	16	aluminum	aluminum	NOUN
admet-497	32	17	crucibles	crucible	NOUN
admet-497	32	18	.	.	PUNCT
admet-497	33	1	the	the	DET
admet-497	33	2	thermal	thermal	ADJ
admet-497	33	3	behavior	behavior	NOUN
admet-497	33	4	of	of	ADP
admet-497	33	5	each	each	DET
admet-497	33	6	sample	sample	NOUN
admet-497	33	7	was	be	AUX
admet-497	33	8	investigated	investigate	VERB
admet-497	33	9	in	in	ADP
admet-497	33	10	a	a	DET
admet-497	33	11	temperature	temperature	NOUN
admet-497	33	12	range	range	NOUN
admet-497	33	13	of	of	ADP
admet-497	33	14	30300	30300	NUM
admet-497	33	15	°	°	ADP
admet-497	33	16	c	c	NOUN
admet-497	33	17	with	with	ADP
admet-497	33	18	10	10	NUM
admet-497	33	19	°	°	NOUN
admet-497	33	20	c	c	NOUN
admet-497	33	21	/	/	SYM
admet-497	33	22	min	min	NOUN
admet-497	33	23	heating	heating	NOUN
admet-497	33	24	rate	rate	NOUN
admet-497	33	25	under	under	ADP
admet-497	33	26	a	a	DET
admet-497	33	27	continuous	continuous	ADJ
admet-497	33	28	flow	flow	NOUN
admet-497	33	29	of	of	ADP
admet-497	33	30	dry	dry	ADJ
admet-497	33	31	nitrogen	nitrogen	NOUN
admet-497	33	32	at	at	ADP
admet-497	33	33	50	50	NUM
admet-497	33	34	ml	ml	NOUN
admet-497	33	35	/	/	SYM
admet-497	33	36	min	min	NOUN
admet-497	33	37	.	.	PROPN
admet-497	33	38	reagents	reagent	NOUN
admet-497	33	39	ciprofloxacin	ciprofloxacin	NOUN
admet-497	33	40	(	(	PUNCT
admet-497	33	41	>	>	X
admet-497	33	42	98	98	NUM
admet-497	33	43	%	%	NOUN
admet-497	33	44	)	)	PUNCT
admet-497	33	45	,	,	PUNCT
admet-497	33	46	resorcinol	resorcinol	NOUN
admet-497	33	47	(	(	PUNCT
admet-497	33	48	>	>	SYM
admet-497	33	49	99	99	NUM
admet-497	33	50	%	%	NOUN
admet-497	33	51	)	)	PUNCT
admet-497	33	52	,	,	PUNCT
admet-497	33	53	toluene	toluene	NOUN
admet-497	33	54	(	(	PUNCT
admet-497	33	55	99.9	99.9	NUM
admet-497	33	56	%	%	NOUN
admet-497	33	57	)	)	PUNCT
admet-497	33	58	,	,	PUNCT
admet-497	33	59	and	and	CCONJ
admet-497	33	60	potassium	potassium	NOUN
admet-497	33	61	chloride	chloride	NOUN
admet-497	33	62	(	(	PUNCT
admet-497	33	63	>	>	SYM
admet-497	33	64	99	99	NUM
admet-497	33	65	%	%	NOUN
admet-497	33	66	)	)	PUNCT
admet-497	33	67	were	be	AUX
admet-497	33	68	from	from	ADP
admet-497	33	69	sigma	sigma	PROPN
admet-497	33	70	-	-	PUNCT
admet-497	33	71	aldrich	aldrich	PROPN
admet-497	33	72	(	(	PUNCT
admet-497	33	73	st	st	PROPN
admet-497	33	74	.	.	PROPN
admet-497	33	75	louis	louis	PROPN
admet-497	33	76	,	,	PUNCT
admet-497	33	77	mo	mo	PROPN
admet-497	33	78	,	,	PUNCT
admet-497	33	79	usa	usa	PROPN
admet-497	33	80	)	)	PUNCT
admet-497	33	81	.	.	PUNCT
admet-497	34	1	sodium	sodium	PROPN
admet-497	34	2	acetate	acetate	PROPN
admet-497	34	3	anhydrous	anhydrous	ADJ
admet-497	34	4	(	(	PUNCT
admet-497	34	5	>	>	SYM
admet-497	34	6	99	99	NUM
admet-497	34	7	%	%	NOUN
admet-497	34	8	)	)	PUNCT
admet-497	34	9	,	,	PUNCT
admet-497	34	10	potassium	potassium	NOUN
admet-497	34	11	dihydrogen	dihydrogen	NOUN
admet-497	34	12	phosphate	phosphate	NOUN
admet-497	34	13	(	(	PUNCT
admet-497	34	14	>	>	SYM
admet-497	34	15	99.5	99.5	NUM
admet-497	34	16	%	%	NOUN
admet-497	34	17	)	)	PUNCT
admet-497	34	18	,	,	PUNCT
admet-497	34	19	and	and	CCONJ
admet-497	34	20	0.5	0.5	NUM
admet-497	34	21	m	m	PROPN
admet-497	34	22	naoh	naoh	NOUN
admet-497	34	23	standard	standard	ADJ
admet-497	34	24	solution	solution	NOUN
admet-497	34	25	(	(	PUNCT
admet-497	34	26	titrisol	titrisol	PROPN
admet-497	34	27	®	®	PROPN
admet-497	34	28	)	)	PUNCT
admet-497	34	29	were	be	AUX
admet-497	34	30	for	for	ADP
admet-497	34	31	merck	merck	PROPN
admet-497	34	32	(	(	PUNCT
admet-497	34	33	darmstad	darmstad	PROPN
admet-497	34	34	,	,	PUNCT
admet-497	34	35	germany	germany	PROPN
admet-497	34	36	)	)	PUNCT
admet-497	34	37	.	.	PUNCT
admet-497	35	1	fassif	fassif	PROPN
admet-497	35	2	(	(	PUNCT
admet-497	35	3	fasted	fast	VERB
admet-497	35	4	state	state	NOUN
admet-497	35	5	simulated	simulate	VERB
admet-497	35	6	intestinal	intestinal	ADJ
admet-497	35	7	fluid	fluid	NOUN
admet-497	35	8	)	)	PUNCT
admet-497	35	9	and	and	CCONJ
admet-497	35	10	fessif	fessif	NOUN
admet-497	35	11	(	(	PUNCT
admet-497	35	12	fed	fed	PROPN
admet-497	35	13	state	state	NOUN
admet-497	35	14	simulated	simulate	VERB
admet-497	35	15	intestinal	intestinal	ADJ
admet-497	35	16	fluid	fluid	NOUN
admet-497	35	17	)	)	PUNCT
admet-497	35	18	powders	powder	NOUN
admet-497	35	19	were	be	AUX
admet-497	35	20	from	from	ADP
admet-497	35	21	biorelevant.com	biorelevant.com	X
admet-497	35	22	(	(	PUNCT
admet-497	35	23	london	london	PROPN
admet-497	35	24	,	,	PUNCT
admet-497	35	25	uk	uk	PROPN
admet-497	35	26	)	)	PUNCT
admet-497	35	27	.	.	PUNCT
admet-497	36	1	the	the	DET
admet-497	36	2	simulated	simulate	VERB
admet-497	36	3	gastrointestinal	gastrointestinal	ADJ
admet-497	36	4	solutions	solution	NOUN
admet-497	36	5	of	of	ADP
admet-497	36	6	fassif	fassif	NOUN
admet-497	36	7	and	and	CCONJ
admet-497	36	8	fessif	fessif	NOUN
admet-497	36	9	were	be	AUX
admet-497	36	10	prepared	prepare	VERB
admet-497	36	11	as	as	SCONJ
admet-497	36	12	specified	specify	VERB
admet-497	36	13	by	by	ADP
admet-497	36	14	the	the	DET
admet-497	36	15	manufacturer	manufacturer	NOUN
admet-497	36	16	.	.	PUNCT
admet-497	37	1	water	water	NOUN
admet-497	37	2	was	be	AUX
admet-497	37	3	purified	purify	VERB
admet-497	37	4	by	by	ADP
admet-497	37	5	a	a	DET
admet-497	37	6	milli	milli	ADJ
admet-497	37	7	-	-	PUNCT
admet-497	37	8	q	q	NOUN
admet-497	37	9	plus	plus	CCONJ
admet-497	37	10	system	system	NOUN
admet-497	37	11	from	from	ADP
admet-497	37	12	millipore	millipore	PROPN
admet-497	37	13	(	(	PUNCT
admet-497	37	14	bedford	bedford	PROPN
admet-497	37	15	,	,	PUNCT
admet-497	37	16	ma	ma	PROPN
admet-497	37	17	,	,	PUNCT
admet-497	37	18	usa	usa	PROPN
admet-497	37	19	)	)	PUNCT
admet-497	37	20	with	with	ADP
admet-497	37	21	resistivity	resistivity	NOUN
admet-497	37	22	of	of	ADP
admet-497	37	23	18.2mω	18.2mω	NUM
admet-497	37	24	cm	cm	NOUN
admet-497	37	25	.	.	PUNCT
admet-497	38	1	methods	method	NOUN
admet-497	38	2	ciprofloxacin	ciprofloxacin	PROPN
admet-497	38	3	cocrystal	cocrystal	PROPN
admet-497	38	4	was	be	AUX
admet-497	38	5	prepared	prepare	VERB
admet-497	38	6	using	use	VERB
admet-497	38	7	slurry	slurry	NOUN
admet-497	38	8	crystallization	crystallization	NOUN
admet-497	38	9	method	method	NOUN
admet-497	38	10	.	.	PUNCT
admet-497	39	1	100	100	NUM
admet-497	39	2	mg	mg	NOUN
admet-497	39	3	of	of	ADP
admet-497	39	4	ciprofloxacin	ciprofloxacin	PROPN
admet-497	39	5	was	be	AUX
admet-497	39	6	admet	admet	PROPN
admet-497	39	7	&	&	CCONJ
admet-497	39	8	dmpk	dmpk	PROPN
admet-497	39	9	6(1	6(1	NUM
admet-497	39	10	)	)	PUNCT
admet-497	39	11	(	(	PUNCT
admet-497	39	12	2018	2018	NUM
admet-497	39	13	)	)	PUNCT
admet-497	39	14	61	61	NUM
admet-497	39	15	-	-	SYM
admet-497	39	16	70	70	NUM
admet-497	39	17	dissolution	dissolution	NOUN
admet-497	39	18	rates	rate	NOUN
admet-497	39	19	of	of	ADP
admet-497	39	20	ciprofloxacin	ciprofloxacin	PROPN
admet-497	39	21	and	and	CCONJ
admet-497	39	22	its	its	PRON
admet-497	39	23	cocrystal	cocrystal	NOUN
admet-497	39	24	with	with	ADP
admet-497	39	25	resorcinol	resorcinol	NOUN
admet-497	39	26	doi	doi	NOUN
admet-497	39	27	:	:	PUNCT
admet-497	39	28	10.5599	10.5599	NUM
admet-497	39	29	/	/	SYM
admet-497	39	30	admet.6.1.497	admet.6.1.497	PROPN
admet-497	39	31	63	63	NUM
admet-497	39	32	mixed	mix	VERB
admet-497	39	33	with	with	ADP
admet-497	39	34	42	42	NUM
admet-497	39	35	mg	mg	NOUN
admet-497	39	36	of	of	ADP
admet-497	39	37	resorcinol	resorcinol	NOUN
admet-497	39	38	in	in	ADP
admet-497	39	39	2	2	NUM
admet-497	39	40	ml	ml	NOUN
admet-497	39	41	of	of	ADP
admet-497	39	42	toluene	toluene	NOUN
admet-497	39	43	.	.	PUNCT
admet-497	40	1	the	the	DET
admet-497	40	2	suspension	suspension	NOUN
admet-497	40	3	was	be	AUX
admet-497	40	4	kept	keep	VERB
admet-497	40	5	under	under	ADP
admet-497	40	6	stirring	stir	VERB
admet-497	40	7	overnight	overnight	ADV
admet-497	40	8	and	and	CCONJ
admet-497	40	9	solid	solid	ADJ
admet-497	40	10	was	be	AUX
admet-497	40	11	collected	collect	VERB
admet-497	40	12	next	next	ADJ
admet-497	40	13	day	day	NOUN
admet-497	40	14	by	by	ADP
admet-497	40	15	filtration	filtration	NOUN
admet-497	40	16	under	under	ADP
admet-497	40	17	vacuum	vacuum	NOUN
admet-497	40	18	for	for	ADP
admet-497	40	19	30	30	NUM
admet-497	40	20	min	min	NOUN
admet-497	40	21	.	.	PROPN
admet-497	41	1	then	then	ADV
admet-497	41	2	,	,	PUNCT
admet-497	41	3	it	it	PRON
admet-497	41	4	was	be	AUX
admet-497	41	5	characterized	characterize	VERB
admet-497	41	6	by	by	ADP
admet-497	41	7	dsc	dsc	NOUN
admet-497	41	8	and	and	CCONJ
admet-497	41	9	powder	powder	NOUN
admet-497	41	10	x	x	NOUN
admet-497	41	11	-	-	NOUN
admet-497	41	12	ray	ray	NOUN
admet-497	41	13	diffraction	diffraction	NOUN
admet-497	41	14	(	(	PUNCT
admet-497	41	15	pxrd	pxrd	PROPN
admet-497	41	16	)	)	PUNCT
admet-497	41	17	(	(	PUNCT
admet-497	41	18	figure	figure	NOUN
admet-497	41	19	1	1	NUM
admet-497	41	20	)	)	PUNCT
admet-497	41	21	.	.	PUNCT
admet-497	42	1	it	it	PRON
admet-497	42	2	can	can	AUX
admet-497	42	3	be	be	AUX
admet-497	42	4	observed	observe	VERB
admet-497	42	5	that	that	SCONJ
admet-497	42	6	the	the	DET
admet-497	42	7	signals	signal	NOUN
admet-497	42	8	corresponding	correspond	VERB
admet-497	42	9	to	to	ADP
admet-497	42	10	the	the	DET
admet-497	42	11	cocrystal	cocrystal	NOUN
admet-497	42	12	are	be	AUX
admet-497	42	13	different	different	ADJ
admet-497	42	14	than	than	ADP
admet-497	42	15	the	the	DET
admet-497	42	16	ones	one	NOUN
admet-497	42	17	of	of	ADP
admet-497	42	18	the	the	DET
admet-497	42	19	pure	pure	ADJ
admet-497	42	20	components	component	NOUN
admet-497	42	21	.	.	PUNCT
admet-497	43	1	the	the	DET
admet-497	43	2	formed	form	VERB
admet-497	43	3	cocrystal	cocrystal	PROPN
admet-497	43	4	had	have	VERB
admet-497	43	5	1:1	1:1	NUM
admet-497	43	6	stoichiometry	stoichiometry	NOUN
admet-497	43	7	.	.	PUNCT
admet-497	44	1	figure	figure	VERB
admet-497	44	2	1	1	NUM
admet-497	44	3	:	:	PUNCT
admet-497	44	4	(	(	PUNCT
admet-497	44	5	a	a	X
admet-497	44	6	)	)	PUNCT
admet-497	44	7	dsc	dsc	NOUN
admet-497	44	8	curve	curve	NOUN
admet-497	44	9	for	for	ADP
admet-497	44	10	resorcinol	resorcinol	NOUN
admet-497	44	11	,	,	PUNCT
admet-497	44	12	the	the	DET
admet-497	44	13	cocrystal	cocrystal	NOUN
admet-497	44	14	,	,	PUNCT
admet-497	44	15	and	and	CCONJ
admet-497	44	16	cip	cip	PROPN
admet-497	44	17	.	.	PUNCT
admet-497	45	1	(	(	PUNCT
admet-497	45	2	b	b	X
admet-497	45	3	)	)	PUNCT
admet-497	45	4	pxrd	pxrd	NOUN
admet-497	45	5	diffractogram	diffractogram	NOUN
admet-497	45	6	for	for	ADP
admet-497	45	7	resorcinol	resorcinol	NOUN
admet-497	45	8	,	,	PUNCT
admet-497	45	9	the	the	DET
admet-497	45	10	cocrystal	cocrystal	NOUN
admet-497	45	11	,	,	PUNCT
admet-497	45	12	and	and	CCONJ
admet-497	45	13	cip	cip	PROPN
admet-497	45	14	.	.	PUNCT
admet-497	46	1	for	for	ADP
admet-497	46	2	dissolution	dissolution	ADJ
admet-497	46	3	rate	rate	NOUN
admet-497	46	4	measurements	measurement	NOUN
admet-497	46	5	the	the	DET
admet-497	46	6	“	"	PUNCT
admet-497	46	7	gi	gi	X
admet-497	46	8	dissolution	dissolution	PROPN
admet-497	46	9	method	method	NOUN
admet-497	46	10	”	"	PUNCT
admet-497	46	11	has	have	AUX
admet-497	46	12	been	be	AUX
admet-497	46	13	followed	follow	VERB
admet-497	46	14	[	[	X
admet-497	46	15	15	15	NUM
admet-497	46	16	]	]	PUNCT
admet-497	46	17	.	.	PUNCT
admet-497	47	1	briefly	briefly	NOUN
admet-497	47	2	,	,	PUNCT
admet-497	47	3	disks	disk	NOUN
admet-497	47	4	of	of	ADP
admet-497	47	5	3	3	NUM
admet-497	47	6	mm	mm	NOUN
admet-497	47	7	diameter	diameter	NOUN
admet-497	47	8	containing	contain	VERB
admet-497	47	9	8	8	NUM
admet-497	47	10	-	-	SYM
admet-497	47	11	10	10	NUM
admet-497	47	12	mg	mg	NOUN
admet-497	47	13	of	of	ADP
admet-497	47	14	drug	drug	NOUN
admet-497	47	15	or	or	CCONJ
admet-497	47	16	cocrystal	cocrystal	ADJ
admet-497	47	17	(	(	PUNCT
admet-497	47	18	8	8	NUM
admet-497	47	19	mg	mg	NOUN
admet-497	47	20	of	of	ADP
admet-497	47	21	cocrystal	cocrystal	NOUN
admet-497	47	22	containing	contain	VERB
admet-497	47	23	around	around	ADV
admet-497	47	24	5	5	NUM
admet-497	47	25	mg	mg	NOUN
admet-497	47	26	of	of	ADP
admet-497	47	27	cip	cip	NOUN
admet-497	47	28	,	,	PUNCT
admet-497	47	29	according	accord	VERB
admet-497	47	30	to	to	ADP
admet-497	47	31	a	a	DET
admet-497	47	32	1:1	1:1	NUM
admet-497	47	33	stoichiometry	stoichiometry	NOUN
admet-497	47	34	)	)	PUNCT
admet-497	47	35	were	be	AUX
admet-497	47	36	prepared	prepare	VERB
admet-497	47	37	by	by	ADP
admet-497	47	38	applying	apply	VERB
admet-497	47	39	a	a	DET
admet-497	47	40	constant	constant	ADJ
admet-497	47	41	pressure	pressure	NOUN
admet-497	47	42	of	of	ADP
admet-497	47	43	0.1	0.1	NUM
admet-497	47	44	ton	ton	NOUN
admet-497	47	45	.	.	PUNCT
admet-497	48	1	a	a	DET
admet-497	48	2	sirius	sirius	PROPN
admet-497	48	3	glpka	glpka	NOUN
admet-497	48	4	system	system	NOUN
admet-497	48	5	was	be	AUX
admet-497	48	6	used	use	VERB
admet-497	48	7	to	to	PART
admet-497	48	8	perform	perform	VERB
admet-497	48	9	the	the	DET
admet-497	48	10	measurements	measurement	NOUN
admet-497	48	11	.	.	PUNCT
admet-497	49	1	temperature	temperature	NOUN
admet-497	49	2	was	be	AUX
admet-497	49	3	25±1	25±1	NUM
admet-497	49	4	°	°	ADP
admet-497	49	5	c	c	NOUN
admet-497	49	6	and	and	CCONJ
admet-497	49	7	ionic	ionic	ADJ
admet-497	49	8	strength	strength	NOUN
admet-497	49	9	was	be	AUX
admet-497	49	10	kept	keep	VERB
admet-497	49	11	constant	constant	ADJ
admet-497	49	12	at	at	ADP
admet-497	49	13	0.15	0.15	NUM
admet-497	49	14	m.	m.	NOUN
admet-497	49	15	study	study	NOUN
admet-497	49	16	was	be	AUX
admet-497	49	17	performed	perform	VERB
admet-497	49	18	at	at	ADP
admet-497	49	19	different	different	ADJ
admet-497	49	20	ph	ph	ADJ
admet-497	49	21	sectors	sector	NOUN
admet-497	49	22	(	(	PUNCT
admet-497	49	23	2.0	2.0	NUM
admet-497	49	24	,	,	PUNCT
admet-497	49	25	4.0	4.0	NUM
admet-497	49	26	,	,	PUNCT
admet-497	49	27	5.5	5.5	NUM
admet-497	49	28	,	,	PUNCT
admet-497	49	29	and	and	CCONJ
admet-497	49	30	7.4	7.4	NUM
admet-497	49	31	)	)	PUNCT
admet-497	49	32	which	which	PRON
admet-497	49	33	are	be	AUX
admet-497	49	34	typically	typically	ADV
admet-497	49	35	encountered	encounter	VERB
admet-497	49	36	in	in	ADP
admet-497	49	37	the	the	DET
admet-497	49	38	gi	gi	NOUN
admet-497	49	39	tract	tract	NOUN
admet-497	49	40	.	.	PUNCT
admet-497	50	1	to	to	PART
admet-497	50	2	perform	perform	VERB
admet-497	50	3	experiments	experiment	NOUN
admet-497	50	4	1.5	1.5	NUM
admet-497	50	5	ml	ml	NOUN
admet-497	50	6	of	of	ADP
admet-497	50	7	a	a	DET
admet-497	50	8	0.125	0.125	NUM
admet-497	50	9	m	m	NOUN
admet-497	50	10	acetate	acetate	NOUN
admet-497	50	11	and	and	CCONJ
admet-497	50	12	0.125	0.125	NUM
admet-497	50	13	m	m	NOUN
admet-497	50	14	phosphate	phosphate	NOUN
admet-497	50	15	buffer	buffer	NOUN
admet-497	50	16	solution	solution	NOUN
admet-497	50	17	at	at	ADP
admet-497	50	18	ph	ph	NOUN
admet-497	50	19	=	=	SYM
admet-497	50	20	1.6	1.6	NUM
admet-497	50	21	was	be	AUX
admet-497	50	22	introduced	introduce	VERB
admet-497	50	23	into	into	ADP
admet-497	50	24	the	the	DET
admet-497	50	25	sample	sample	NOUN
admet-497	50	26	vial	vial	NOUN
admet-497	50	27	.	.	PUNCT
admet-497	51	1	then	then	ADV
admet-497	51	2	,	,	PUNCT
admet-497	51	3	the	the	DET
admet-497	51	4	instrument	instrument	NOUN
admet-497	51	5	added	add	VERB
admet-497	51	6	13.5	13.5	NUM
admet-497	51	7	ml	ml	NOUN
admet-497	51	8	of	of	ADP
admet-497	51	9	0.15	0.15	NUM
admet-497	51	10	m	m	PROPN
admet-497	51	11	aqueous	aqueous	ADJ
admet-497	51	12	kcl	kcl	NOUN
admet-497	51	13	solution	solution	NOUN
admet-497	51	14	,	,	PUNCT
admet-497	51	15	which	which	PRON
admet-497	51	16	raised	raise	VERB
admet-497	51	17	initial	initial	ADJ
admet-497	51	18	ph	ph	NOUN
admet-497	51	19	around	around	ADP
admet-497	51	20	2	2	NUM
admet-497	51	21	.	.	PUNCT
admet-497	52	1	dissolution	dissolution	PROPN
admet-497	52	2	started	start	VERB
admet-497	52	3	and	and	CCONJ
admet-497	52	4	the	the	DET
admet-497	52	5	medium	medium	NOUN
admet-497	52	6	was	be	AUX
admet-497	52	7	stirred	stir	VERB
admet-497	52	8	at	at	ADP
admet-497	52	9	a	a	DET
admet-497	52	10	constant	constant	ADJ
admet-497	52	11	rate	rate	NOUN
admet-497	52	12	throughout	throughout	ADP
admet-497	52	13	the	the	DET
admet-497	52	14	experiment	experiment	NOUN
admet-497	52	15	.	.	PUNCT
admet-497	53	1	after	after	ADP
admet-497	53	2	30	30	NUM
admet-497	53	3	minutes	minute	NOUN
admet-497	53	4	,	,	PUNCT
admet-497	53	5	0.5	0.5	NUM
admet-497	53	6	m	m	NOUN
admet-497	53	7	koh	koh	PROPN
admet-497	53	8	solution	solution	NOUN
admet-497	53	9	was	be	AUX
admet-497	53	10	automatically	automatically	ADV
admet-497	53	11	dispensed	dispense	VERB
admet-497	53	12	to	to	PART
admet-497	53	13	adjust	adjust	VERB
admet-497	53	14	to	to	ADP
admet-497	53	15	the	the	DET
admet-497	53	16	next	next	ADJ
admet-497	53	17	ph	ph	NOUN
admet-497	53	18	,	,	PUNCT
admet-497	53	19	and	and	CCONJ
admet-497	53	20	so	so	ADV
admet-497	53	21	on	on	ADV
admet-497	53	22	.	.	PUNCT
admet-497	54	1	in	in	ADP
admet-497	54	2	all	all	DET
admet-497	54	3	experiments	experiment	NOUN
admet-497	54	4	uv	uv	NOUN
admet-497	54	5	-	-	PUNCT
admet-497	54	6	vis	vis	X
admet-497	54	7	spectra	spectra	NOUN
admet-497	54	8	were	be	AUX
admet-497	54	9	recorded	record	VERB
admet-497	54	10	at	at	ADP
admet-497	54	11	fixed	fix	VERB
admet-497	54	12	intervals	interval	NOUN
admet-497	54	13	,	,	PUNCT
admet-497	54	14	normally	normally	ADV
admet-497	54	15	30	30	NUM
admet-497	54	16	s.	s.	PROPN
admet-497	54	17	dissolution	dissolution	PROPN
admet-497	54	18	rate	rate	NOUN
admet-497	54	19	was	be	AUX
admet-497	54	20	determined	determine	VERB
admet-497	54	21	individually	individually	ADV
admet-497	54	22	at	at	ADP
admet-497	54	23	each	each	DET
admet-497	54	24	ph	ph	ADJ
admet-497	54	25	sector	sector	NOUN
admet-497	54	26	,	,	PUNCT
admet-497	54	27	and	and	CCONJ
admet-497	54	28	then	then	ADV
admet-497	54	29	experiments	experiment	NOUN
admet-497	54	30	were	be	AUX
admet-497	54	31	repeated	repeat	VERB
admet-497	54	32	in	in	ADP
admet-497	54	33	a	a	DET
admet-497	54	34	full	full	ADJ
admet-497	54	35	sequence	sequence	NOUN
admet-497	54	36	of	of	ADP
admet-497	54	37	phs	phs	NOUN
admet-497	54	38	(	(	PUNCT
admet-497	54	39	from	from	ADP
admet-497	54	40	2.0	2.0	NUM
admet-497	54	41	to	to	ADP
admet-497	54	42	7.4	7.4	NUM
admet-497	54	43	)	)	PUNCT
admet-497	54	44	staying	stay	VERB
admet-497	54	45	30	30	NUM
admet-497	54	46	minutes	minute	NOUN
admet-497	54	47	at	at	ADP
admet-497	54	48	each	each	DET
admet-497	54	49	ph	ph	NOUN
admet-497	54	50	.	.	PUNCT
admet-497	54	51	additionally	additionally	ADV
admet-497	54	52	,	,	PUNCT
admet-497	54	53	dissolution	dissolution	ADJ
admet-497	54	54	rates	rate	NOUN
admet-497	54	55	were	be	AUX
admet-497	54	56	also	also	ADV
admet-497	54	57	determined	determine	VERB
admet-497	54	58	in	in	ADP
admet-497	54	59	the	the	DET
admet-497	54	60	acetate	acetate	NOUN
admet-497	54	61	/	/	SYM
admet-497	54	62	phosphate	phosphate	NOUN
admet-497	54	63	buffer	buffer	NOUN
admet-497	54	64	at	at	ADP
admet-497	54	65	ph	ph	ADJ
admet-497	54	66	5.0	5.0	NUM
admet-497	54	67	and	and	CCONJ
admet-497	54	68	c.	c.	NOUN
admet-497	54	69	ràfols	ràfol	NOUN
admet-497	54	70	et	et	PROPN
admet-497	54	71	al	al	PROPN
admet-497	54	72	.	.	PROPN
admet-497	54	73	admet	admet	PROPN
admet-497	54	74	&	&	CCONJ
admet-497	54	75	dmpk	dmpk	PROPN
admet-497	54	76	6(1	6(1	NUM
admet-497	54	77	)	)	PUNCT
admet-497	54	78	(	(	PUNCT
admet-497	54	79	2018	2018	NUM
admet-497	54	80	)	)	PUNCT
admet-497	54	81	61	61	NUM
admet-497	54	82	-	-	SYM
admet-497	54	83	70	70	NUM
admet-497	54	84	64	64	NUM
admet-497	54	85	6.5	6.5	NUM
admet-497	54	86	,	,	PUNCT
admet-497	54	87	and	and	CCONJ
admet-497	54	88	in	in	ADP
admet-497	54	89	15	15	NUM
admet-497	54	90	ml	ml	NOUN
admet-497	54	91	of	of	ADP
admet-497	54	92	two	two	NUM
admet-497	54	93	simulated	simulate	VERB
admet-497	54	94	gastrointestinal	gastrointestinal	ADJ
admet-497	54	95	fluids	fluid	NOUN
admet-497	54	96	(	(	PUNCT
admet-497	54	97	fessif	fessif	INTJ
admet-497	54	98	,	,	PUNCT
admet-497	54	99	ph	ph	NOUN
admet-497	54	100	5.0	5.0	NUM
admet-497	54	101	and	and	CCONJ
admet-497	54	102	fassif	fassif	NOUN
admet-497	54	103	,	,	PUNCT
admet-497	54	104	ph	ph	X
admet-497	54	105	6.5	6.5	NUM
admet-497	54	106	)	)	PUNCT
admet-497	54	107	.	.	PUNCT
admet-497	55	1	the	the	DET
admet-497	55	2	concentration	concentration	NOUN
admet-497	55	3	of	of	ADP
admet-497	55	4	sample	sample	NOUN
admet-497	55	5	in	in	ADP
admet-497	55	6	solution	solution	NOUN
admet-497	55	7	at	at	ADP
admet-497	55	8	each	each	DET
admet-497	55	9	time	time	NOUN
admet-497	55	10	point	point	NOUN
admet-497	55	11	is	be	AUX
admet-497	55	12	determined	determine	VERB
admet-497	55	13	from	from	ADP
admet-497	55	14	the	the	DET
admet-497	55	15	spectroscopic	spectroscopic	ADJ
admet-497	55	16	data	datum	NOUN
admet-497	55	17	in	in	ADP
admet-497	55	18	the	the	DET
admet-497	55	19	320	320	NUM
admet-497	55	20	-	-	SYM
admet-497	55	21	410	410	NUM
admet-497	55	22	nm	nm	ADJ
admet-497	55	23	wavelength	wavelength	NOUN
admet-497	55	24	range	range	NOUN
admet-497	55	25	,	,	PUNCT
admet-497	55	26	using	use	VERB
admet-497	55	27	previously	previously	ADV
admet-497	55	28	determined	determine	VERB
admet-497	55	29	molar	molar	ADJ
admet-497	55	30	extinction	extinction	NOUN
admet-497	55	31	coefficients	coefficient	NOUN
admet-497	55	32	.	.	PUNCT
admet-497	56	1	in	in	ADP
admet-497	56	2	this	this	DET
admet-497	56	3	range	range	NOUN
admet-497	56	4	solutions	solution	NOUN
admet-497	56	5	of	of	ADP
admet-497	56	6	fassif	fassif	NOUN
admet-497	56	7	,	,	PUNCT
admet-497	56	8	fessif	fessif	NOUN
admet-497	56	9	and	and	CCONJ
admet-497	56	10	resorcinol	resorcinol	NOUN
admet-497	56	11	present	present	ADJ
admet-497	56	12	a	a	DET
admet-497	56	13	minimum	minimum	ADJ
admet-497	56	14	absorbance	absorbance	NOUN
admet-497	56	15	so	so	SCONJ
admet-497	56	16	that	that	SCONJ
admet-497	56	17	they	they	PRON
admet-497	56	18	do	do	AUX
admet-497	56	19	n’t	not	PART
admet-497	56	20	interfere	interfere	VERB
admet-497	56	21	in	in	ADP
admet-497	56	22	the	the	DET
admet-497	56	23	quantification	quantification	NOUN
admet-497	56	24	of	of	ADP
admet-497	56	25	ciprofloxacin	ciprofloxacin	PROPN
admet-497	56	26	.	.	PUNCT
admet-497	57	1	data	datum	NOUN
admet-497	57	2	corresponding	correspond	VERB
admet-497	57	3	to	to	ADP
admet-497	57	4	saturated	saturate	VERB
admet-497	57	5	signals	signal	NOUN
admet-497	57	6	were	be	AUX
admet-497	57	7	excluded	exclude	VERB
admet-497	57	8	for	for	ADP
admet-497	57	9	the	the	DET
admet-497	57	10	calculation	calculation	NOUN
admet-497	57	11	.	.	PUNCT
admet-497	58	1	equation	equation	NOUN
admet-497	58	2	1	1	NUM
admet-497	58	3	was	be	AUX
admet-497	58	4	used	use	VERB
admet-497	58	5	to	to	PART
admet-497	58	6	calculate	calculate	VERB
admet-497	58	7	the	the	DET
admet-497	58	8	dissolution	dissolution	NOUN
admet-497	58	9	rate	rate	NOUN
admet-497	58	10	of	of	ADP
admet-497	58	11	the	the	DET
admet-497	58	12	compounds	compound	NOUN
admet-497	58	13	,	,	PUNCT
admet-497	58	14			ADJ
admet-497	58	15			NOUN
admet-497	58	16	(	(	PUNCT
admet-497	58	17	)	)	PUNCT
admet-497	58	18	0dx	0dx	NOUN
admet-497	58	19	=	=	SYM
admet-497	59	1	1	1	NUM
admet-497	59	2	-	-	SYM
admet-497	59	3	e	e	NOUN
admet-497	59	4	k	k	PROPN
admet-497	59	5	t	t	PROPN
admet-497	59	6	t	t	PROPN
admet-497	59	7	st	st	PROPN
admet-497	59	8			PROPN
admet-497	59	9			PROPN
admet-497	59	10			PROPN
admet-497	59	11			PROPN
admet-497	60	1			PROPN
admet-497	60	2			NOUN
admet-497	60	3	(	(	PUNCT
admet-497	60	4	1	1	NUM
admet-497	60	5	)	)	PUNCT
admet-497	60	6	where	where	SCONJ
admet-497	60	7	[	[	X
admet-497	60	8	x]t	x]t	NOUN
admet-497	60	9	is	be	AUX
admet-497	60	10	the	the	DET
admet-497	60	11	weight	weight	NOUN
admet-497	60	12	(	(	PUNCT
admet-497	60	13	in	in	ADP
admet-497	60	14	grams	gram	NOUN
admet-497	60	15	)	)	PUNCT
admet-497	60	16	of	of	ADP
admet-497	60	17	the	the	DET
admet-497	60	18	compound	compound	NOUN
admet-497	60	19	in	in	ADP
admet-497	60	20	solution	solution	NOUN
admet-497	60	21	at	at	ADP
admet-497	60	22	time	time	NOUN
admet-497	60	23	t	t	PROPN
admet-497	60	24	(	(	PUNCT
admet-497	60	25	min	min	NOUN
admet-497	60	26	)	)	PUNCT
admet-497	60	27	,	,	PUNCT
admet-497	60	28	s	s	VERB
admet-497	60	29	is	be	AUX
admet-497	60	30	the	the	DET
admet-497	60	31	extrapolated	extrapolated	ADJ
admet-497	60	32	solubility	solubility	NOUN
admet-497	60	33	(	(	PUNCT
admet-497	60	34	g	g	NOUN
admet-497	60	35	)	)	PUNCT
admet-497	60	36	of	of	ADP
admet-497	60	37	the	the	DET
admet-497	60	38	drug	drug	NOUN
admet-497	60	39	,	,	PUNCT
admet-497	60	40	kd	kd	PROPN
admet-497	60	41	is	be	AUX
admet-497	60	42	the	the	DET
admet-497	60	43	rate	rate	NOUN
admet-497	60	44	constant	constant	ADJ
admet-497	60	45	for	for	ADP
admet-497	60	46	dissolution	dissolution	NOUN
admet-497	60	47	(	(	PUNCT
admet-497	60	48	min	min	NOUN
admet-497	60	49	-1	-1	ADJ
admet-497	60	50	)	)	PUNCT
admet-497	60	51	,	,	PUNCT
admet-497	60	52	and	and	CCONJ
admet-497	60	53	t0	t0	PROPN
admet-497	60	54	is	be	AUX
admet-497	60	55	a	a	DET
admet-497	60	56	term	term	NOUN
admet-497	60	57	allowing	allow	VERB
admet-497	60	58	for	for	ADP
admet-497	60	59	a	a	DET
admet-497	60	60	temporal	temporal	ADJ
admet-497	60	61	offset	offset	NOUN
admet-497	60	62	.	.	PUNCT
admet-497	61	1	the	the	DET
admet-497	61	2	dissolution	dissolution	NOUN
admet-497	61	3	rate	rate	NOUN
admet-497	61	4	(	(	PUNCT
admet-497	61	5	g	g	PROPN
admet-497	61	6	min	min	PROPN
admet-497	61	7	-1	-1	PUNCT
admet-497	61	8	)	)	PUNCT
admet-497	61	9	is	be	AUX
admet-497	61	10	given	give	VERB
admet-497	61	11	by	by	ADP
admet-497	61	12	the	the	DET
admet-497	61	13	product	product	NOUN
admet-497	61	14	kd·s	kd·s	PROPN
admet-497	61	15	.	.	PUNCT
admet-497	62	1	after	after	SCONJ
admet-497	62	2	the	the	DET
admet-497	62	3	dissolution	dissolution	ADJ
admet-497	62	4	rate	rate	NOUN
admet-497	62	5	experiments	experiment	NOUN
admet-497	62	6	,	,	PUNCT
admet-497	62	7	the	the	DET
admet-497	62	8	solid	solid	ADJ
admet-497	62	9	state	state	NOUN
admet-497	62	10	of	of	ADP
admet-497	62	11	the	the	DET
admet-497	62	12	remaining	remain	VERB
admet-497	62	13	disks	disk	NOUN
admet-497	62	14	was	be	AUX
admet-497	62	15	analysed	analyse	VERB
admet-497	62	16	using	use	VERB
admet-497	62	17	pxrd	pxrd	NOUN
admet-497	62	18	.	.	PUNCT
admet-497	63	1	results	result	NOUN
admet-497	63	2	and	and	CCONJ
admet-497	63	3	discussion	discussion	NOUN
admet-497	63	4	dissolution	dissolution	NOUN
admet-497	63	5	behaviour	behaviour	NOUN
admet-497	63	6	of	of	ADP
admet-497	63	7	ionisable	ionisable	ADJ
admet-497	63	8	compounds	compound	NOUN
admet-497	63	9	is	be	AUX
admet-497	63	10	strongly	strongly	ADV
admet-497	63	11	dependent	dependent	ADJ
admet-497	63	12	on	on	ADP
admet-497	63	13	ph	ph	ADJ
admet-497	63	14	value	value	NOUN
admet-497	63	15	of	of	ADP
admet-497	63	16	the	the	DET
admet-497	63	17	surrounding	surround	VERB
admet-497	63	18	medium	medium	NOUN
admet-497	63	19	.	.	PUNCT
admet-497	64	1	as	as	SCONJ
admet-497	64	2	drug	drug	NOUN
admet-497	64	3	moves	move	NOUN
admet-497	64	4	throughout	throughout	ADP
admet-497	64	5	the	the	DET
admet-497	64	6	gastrointestinal	gastrointestinal	ADJ
admet-497	64	7	tract	tract	NOUN
admet-497	64	8	(	(	PUNCT
admet-497	64	9	git	git	NOUN
admet-497	64	10	)	)	PUNCT
admet-497	64	11	it	it	PRON
admet-497	64	12	is	be	AUX
admet-497	64	13	exposed	expose	VERB
admet-497	64	14	to	to	ADP
admet-497	64	15	different	different	ADJ
admet-497	64	16	ph	ph	ADJ
admet-497	64	17	environments	environment	NOUN
admet-497	64	18	that	that	PRON
admet-497	64	19	affect	affect	VERB
admet-497	64	20	its	its	PRON
admet-497	64	21	degree	degree	NOUN
admet-497	64	22	of	of	ADP
admet-497	64	23	ionization	ionization	NOUN
admet-497	64	24	,	,	PUNCT
admet-497	64	25	solubility	solubility	NOUN
admet-497	64	26	,	,	PUNCT
admet-497	64	27	and	and	CCONJ
admet-497	64	28	thus	thus	ADV
admet-497	64	29	dissolution	dissolution	NOUN
admet-497	64	30	or	or	CCONJ
admet-497	64	31	precipitation	precipitation	NOUN
admet-497	64	32	,	,	PUNCT
admet-497	64	33	according	accord	VERB
admet-497	64	34	to	to	ADP
admet-497	64	35	the	the	DET
admet-497	64	36	drug	drug	NOUN
admet-497	64	37	ionization	ionization	NOUN
admet-497	64	38	constants	constant	NOUN
admet-497	64	39	.	.	PUNCT
admet-497	65	1	cip	cip	PROPN
admet-497	65	2	is	be	AUX
admet-497	65	3	a	a	DET
admet-497	65	4	zwitterionic	zwitterionic	ADJ
admet-497	65	5	compound	compound	NOUN
admet-497	65	6	with	with	ADP
admet-497	65	7	pka1	pka1	PROPN
admet-497	65	8	=	=	PROPN
admet-497	65	9	6.20±0.04	6.20±0.04	NOUN
admet-497	65	10	and	and	CCONJ
admet-497	65	11	pka2	pka2	NOUN
admet-497	65	12	=	=	SYM
admet-497	66	1	8.56±0.06	8.56±0.06	PROPN
admet-497	66	2	(	(	PUNCT
admet-497	66	3	values	value	NOUN
admet-497	66	4	provided	provide	VERB
admet-497	66	5	at	at	ADP
admet-497	66	6	25	25	NUM
admet-497	66	7	°	°	NOUN
admet-497	66	8	c	c	NOUN
admet-497	66	9	and	and	CCONJ
admet-497	66	10	0.15	0.15	NUM
admet-497	66	11	m	m	NOUN
admet-497	66	12	ionic	ionic	ADJ
admet-497	66	13	strength	strength	NOUN
admet-497	66	14	)	)	PUNCT
admet-497	67	1	[	[	X
admet-497	67	2	16	16	NUM
admet-497	67	3	]	]	PUNCT
admet-497	67	4	.	.	PUNCT
admet-497	68	1	however	however	ADV
admet-497	68	2	,	,	PUNCT
admet-497	68	3	cip	cip	PROPN
admet-497	68	4	exists	exist	VERB
admet-497	68	5	in	in	ADP
admet-497	68	6	four	four	NUM
admet-497	68	7	different	different	ADJ
admet-497	68	8	microspecies	microspecie	NOUN
admet-497	68	9	(	(	PUNCT
admet-497	68	10	x	x	X
admet-497	68	11	,	,	PUNCT
admet-497	68	12	xh	xh	PROPN
admet-497	68	13	±	±	PROPN
admet-497	68	14	,	,	PUNCT
admet-497	68	15	xh	xh	PROPN
admet-497	68	16	0	0	NUM
admet-497	68	17	,	,	PUNCT
admet-497	68	18	and	and	CCONJ
admet-497	68	19	xh2	xh2	NOUN
admet-497	68	20	+	+	CCONJ
admet-497	68	21	)	)	PUNCT
admet-497	68	22	in	in	ADP
admet-497	68	23	solution	solution	NOUN
admet-497	68	24	.	.	PUNCT
admet-497	69	1	völgyi	völgyi	PROPN
admet-497	69	2	et	et	PROPN
admet-497	69	3	al	al	PROPN
admet-497	69	4	.	.	PUNCT
admet-497	70	1	[	[	X
admet-497	70	2	17	17	NUM
admet-497	70	3	]	]	PUNCT
admet-497	70	4	studied	study	VERB
admet-497	70	5	the	the	DET
admet-497	70	6	acid	acid	NOUN
admet-497	70	7	base	base	NOUN
admet-497	70	8	equilibria	equilibrium	NOUN
admet-497	70	9	of	of	ADP
admet-497	70	10	cip	cip	NOUN
admet-497	70	11	and	and	CCONJ
admet-497	70	12	determined	determine	VERB
admet-497	70	13	its	its	PRON
admet-497	70	14	protonation	protonation	NOUN
admet-497	70	15	macroconstants	macroconstant	NOUN
admet-497	70	16	and	and	CCONJ
admet-497	70	17	microconstants	microconstant	NOUN
admet-497	70	18	.	.	PUNCT
admet-497	71	1	figure	figure	NOUN
admet-497	71	2	2	2	NUM
admet-497	71	3	shows	show	VERB
admet-497	71	4	the	the	DET
admet-497	71	5	species	specie	NOUN
admet-497	71	6	distribution	distribution	NOUN
admet-497	71	7	curve	curve	NOUN
admet-497	71	8	of	of	ADP
admet-497	71	9	this	this	DET
admet-497	71	10	compound	compound	NOUN
admet-497	71	11	according	accord	VERB
admet-497	71	12	to	to	ADP
admet-497	71	13	the	the	DET
admet-497	71	14	values	value	NOUN
admet-497	71	15	provided	provide	VERB
admet-497	71	16	in	in	ADP
admet-497	71	17	the	the	DET
admet-497	71	18	study	study	NOUN
admet-497	71	19	.	.	PUNCT
admet-497	72	1	the	the	DET
admet-497	72	2	zwitterionic	zwitterionic	ADJ
admet-497	72	3	species	specie	NOUN
admet-497	72	4	is	be	AUX
admet-497	72	5	always	always	ADV
admet-497	72	6	predominant	predominant	ADJ
admet-497	72	7	relative	relative	ADJ
admet-497	72	8	to	to	ADP
admet-497	72	9	the	the	DET
admet-497	72	10	non	non	ADJ
admet-497	72	11	-	-	ADJ
admet-497	72	12	charged	charge	VERB
admet-497	72	13	species	specie	NOUN
admet-497	72	14	independently	independently	ADV
admet-497	72	15	of	of	ADP
admet-497	72	16	the	the	DET
admet-497	72	17	ph	ph	NOUN
admet-497	72	18	of	of	ADP
admet-497	72	19	the	the	DET
admet-497	72	20	solution	solution	NOUN
admet-497	72	21	.	.	PUNCT
admet-497	73	1	cip	cip	NOUN
admet-497	73	2	is	be	AUX
admet-497	73	3	positively	positively	ADV
admet-497	73	4	charged	charge	VERB
admet-497	73	5	at	at	ADP
admet-497	73	6	low	low	ADJ
admet-497	73	7	ph	ph	ADJ
admet-497	73	8	values	value	NOUN
admet-497	73	9	,	,	PUNCT
admet-497	73	10	and	and	CCONJ
admet-497	73	11	its	its	PRON
admet-497	73	12	ionization	ionization	NOUN
admet-497	73	13	degree	degree	NOUN
admet-497	73	14	decreases	decrease	NOUN
admet-497	73	15	as	as	ADP
admet-497	73	16	ph	ph	ADJ
admet-497	73	17	increases	increase	NOUN
admet-497	73	18	.	.	PUNCT
admet-497	74	1	the	the	DET
admet-497	74	2	maximum	maximum	ADJ
admet-497	74	3	percentage	percentage	NOUN
admet-497	74	4	of	of	ADP
admet-497	74	5	zwitterionic	zwitterionic	ADJ
admet-497	74	6	form	form	NOUN
admet-497	74	7	and	and	CCONJ
admet-497	74	8	neutral	neutral	ADJ
admet-497	74	9	forms	form	NOUN
admet-497	74	10	exist	exist	VERB
admet-497	74	11	at	at	ADP
admet-497	74	12	ph	ph	ADJ
admet-497	74	13	7.3	7.3	NUM
admet-497	74	14	,	,	PUNCT
admet-497	74	15	where	where	SCONJ
admet-497	74	16	cip	cip	NOUN
admet-497	74	17	has	have	VERB
admet-497	74	18	a	a	DET
admet-497	74	19	log	log	NOUN
admet-497	74	20	s0	s0	NOUN
admet-497	74	21	around	around	ADP
admet-497	74	22	-3.7	-3.7	NOUN
admet-497	74	23	(	(	PUNCT
admet-497	74	24	-3.62	-3.62	ADP
admet-497	74	25	[	[	X
admet-497	74	26	18	18	NUM
admet-497	74	27	]	]	PUNCT
admet-497	74	28	,	,	PUNCT
admet-497	74	29	-3.72	-3.72	NOUN
admet-497	74	30	[	[	X
admet-497	74	31	19	19	NUM
admet-497	74	32	]	]	PUNCT
admet-497	74	33	,	,	PUNCT
admet-497	74	34	and	and	CCONJ
admet-497	74	35	-3.76	-3.76	NUM
admet-497	74	36	measured	measure	VERB
admet-497	74	37	in	in	ADP
admet-497	74	38	this	this	DET
admet-497	74	39	work	work	NOUN
admet-497	74	40	by	by	ADP
admet-497	74	41	the	the	DET
admet-497	74	42	shake	shake	NOUN
admet-497	74	43	-	-	PUNCT
admet-497	74	44	flask	flask	NOUN
admet-497	74	45	method	method	NOUN
admet-497	74	46	according	accord	VERB
admet-497	74	47	to	to	ADP
admet-497	74	48	[	[	X
admet-497	74	49	20	20	NUM
admet-497	74	50	]	]	NUM
admet-497	74	51	)	)	PUNCT
admet-497	74	52	.	.	PUNCT
admet-497	75	1	at	at	ADP
admet-497	75	2	higher	high	ADJ
admet-497	75	3	ph	ph	ADJ
admet-497	75	4	values	value	NOUN
admet-497	75	5	,	,	PUNCT
admet-497	75	6	ionization	ionization	NOUN
admet-497	75	7	degree	degree	NOUN
admet-497	75	8	rises	rise	VERB
admet-497	75	9	again	again	ADV
admet-497	75	10	due	due	ADP
admet-497	75	11	to	to	ADP
admet-497	75	12	the	the	DET
admet-497	75	13	deprotonation	deprotonation	NOUN
admet-497	75	14	of	of	ADP
admet-497	75	15	the	the	DET
admet-497	75	16	basic	basic	ADJ
admet-497	75	17	group	group	NOUN
admet-497	75	18	.	.	PUNCT
admet-497	76	1	on	on	ADP
admet-497	76	2	the	the	DET
admet-497	76	3	contrary	contrary	NOUN
admet-497	76	4	,	,	PUNCT
admet-497	76	5	resorcinol	resorcinol	NOUN
admet-497	76	6	is	be	AUX
admet-497	76	7	a	a	DET
admet-497	76	8	highly	highly	ADV
admet-497	76	9	soluble	soluble	ADJ
admet-497	76	10	very	very	ADV
admet-497	76	11	weak	weak	ADJ
admet-497	76	12	diacid	diacid	NOUN
admet-497	76	13	which	which	PRON
admet-497	76	14	remains	remain	VERB
admet-497	76	15	non‐ionized	non‐ionized	ADJ
admet-497	76	16	(	(	PUNCT
admet-497	76	17	neutral	neutral	ADJ
admet-497	76	18	)	)	PUNCT
admet-497	76	19	in	in	ADP
admet-497	76	20	the	the	DET
admet-497	76	21	whole	whole	ADJ
admet-497	76	22	ph	ph	ADJ
admet-497	76	23	range	range	NOUN
admet-497	76	24	between	between	ADP
admet-497	76	25	2	2	NUM
admet-497	76	26	and	and	CCONJ
admet-497	76	27	7.4	7.4	NUM
admet-497	76	28	.	.	PUNCT
admet-497	77	1	figure	figure	NOUN
admet-497	77	2	3	3	NUM
admet-497	77	3	shows	show	VERB
admet-497	77	4	the	the	DET
admet-497	77	5	aqueous	aqueous	ADJ
admet-497	77	6	dissolution	dissolution	NOUN
admet-497	77	7	profile	profile	NOUN
admet-497	77	8	at	at	ADP
admet-497	77	9	separate	separate	ADJ
admet-497	77	10	ph	ph	ADJ
admet-497	77	11	sectors	sector	NOUN
admet-497	77	12	for	for	ADP
admet-497	77	13	ciprofloxacin	ciprofloxacin	PROPN
admet-497	77	14	and	and	CCONJ
admet-497	77	15	its	its	PRON
admet-497	77	16	cocrystal	cocrystal	NOUN
admet-497	77	17	with	with	ADP
admet-497	77	18	resorcinol	resorcinol	NOUN
admet-497	77	19	(	(	PUNCT
admet-497	77	20	cip	cip	NOUN
admet-497	77	21	-	-	PUNCT
admet-497	77	22	r	r	NOUN
admet-497	77	23	)	)	PUNCT
admet-497	77	24	.	.	PUNCT
admet-497	78	1	the	the	DET
admet-497	78	2	dissolution	dissolution	NOUN
admet-497	78	3	rate	rate	NOUN
admet-497	78	4	reached	reach	VERB
admet-497	78	5	a	a	DET
admet-497	78	6	maximum	maximum	ADJ
admet-497	78	7	value	value	NOUN
admet-497	78	8	at	at	ADP
admet-497	78	9	ph	ph	PROPN
admet-497	78	10	2	2	NUM
admet-497	78	11	,	,	PUNCT
admet-497	78	12	where	where	SCONJ
admet-497	78	13	both	both	PRON
admet-497	78	14	cip	cip	NOUN
admet-497	78	15	and	and	CCONJ
admet-497	78	16	cip	cip	NOUN
admet-497	78	17	-	-	PUNCT
admet-497	78	18	r	r	NOUN
admet-497	78	19	totally	totally	ADV
admet-497	78	20	dissolve	dissolve	VERB
admet-497	78	21	.	.	PUNCT
admet-497	79	1	as	as	ADP
admet-497	79	2	ph	ph	NOUN
admet-497	79	3	of	of	ADP
admet-497	79	4	the	the	DET
admet-497	79	5	medium	medium	ADJ
admet-497	79	6	increases	increase	NOUN
admet-497	79	7	,	,	PUNCT
admet-497	79	8	the	the	DET
admet-497	79	9	percentage	percentage	NOUN
admet-497	79	10	of	of	ADP
admet-497	79	11	cip	cip	NOUN
admet-497	79	12	dissolved	dissolve	VERB
admet-497	79	13	and	and	CCONJ
admet-497	79	14	its	its	PRON
admet-497	79	15	dissolution	dissolution	NOUN
admet-497	79	16	rate	rate	NOUN
admet-497	79	17	start	start	VERB
admet-497	79	18	to	to	PART
admet-497	79	19	decrease	decrease	VERB
admet-497	79	20	,	,	PUNCT
admet-497	79	21	as	as	SCONJ
admet-497	79	22	stated	state	VERB
admet-497	79	23	in	in	ADP
admet-497	79	24	table	table	NOUN
admet-497	79	25	1	1	NUM
admet-497	79	26	.	.	PUNCT
admet-497	80	1	admet	admet	PROPN
admet-497	80	2	&	&	CCONJ
admet-497	80	3	dmpk	dmpk	PROPN
admet-497	80	4	6(1	6(1	NUM
admet-497	80	5	)	)	PUNCT
admet-497	80	6	(	(	PUNCT
admet-497	80	7	2018	2018	NUM
admet-497	80	8	)	)	PUNCT
admet-497	80	9	61	61	NUM
admet-497	80	10	-	-	SYM
admet-497	80	11	70	70	NUM
admet-497	80	12	dissolution	dissolution	NOUN
admet-497	80	13	rates	rate	NOUN
admet-497	80	14	of	of	ADP
admet-497	80	15	ciprofloxacin	ciprofloxacin	PROPN
admet-497	80	16	and	and	CCONJ
admet-497	80	17	its	its	PRON
admet-497	80	18	cocrystal	cocrystal	NOUN
admet-497	80	19	with	with	ADP
admet-497	80	20	resorcinol	resorcinol	NOUN
admet-497	80	21	doi	doi	NOUN
admet-497	80	22	:	:	PUNCT
admet-497	80	23	10.5599	10.5599	NUM
admet-497	80	24	/	/	SYM
admet-497	80	25	admet.6.1.497	admet.6.1.497	PROPN
admet-497	80	26	65	65	NUM
admet-497	80	27	figure	figure	NOUN
admet-497	80	28	2	2	NUM
admet-497	80	29	:	:	PUNCT
admet-497	80	30	species	specie	NOUN
admet-497	80	31	distribution	distribution	NOUN
admet-497	80	32	diagram	diagram	NOUN
admet-497	80	33	for	for	ADP
admet-497	80	34	cip	cip	NOUN
admet-497	80	35	,	,	PUNCT
admet-497	80	36	according	accord	VERB
admet-497	80	37	to	to	ADP
admet-497	80	38	the	the	DET
admet-497	80	39	acidity	acidity	NOUN
admet-497	80	40	macroconstant	macroconstant	NOUN
admet-497	80	41	and	and	CCONJ
admet-497	80	42	microconstantvalues	microconstantvalue	NOUN
admet-497	80	43	provided	provide	VERB
admet-497	80	44	in	in	ADP
admet-497	80	45	[	[	X
admet-497	80	46	17	17	NUM
admet-497	80	47	]	]	PUNCT
admet-497	80	48	.	.	PUNCT
admet-497	81	1	table	table	NOUN
admet-497	81	2	1	1	NUM
admet-497	81	3	:	:	PUNCT
admet-497	81	4	percentage	percentage	NOUN
admet-497	81	5	of	of	ADP
admet-497	81	6	cip	cip	NOUN
admet-497	81	7	dissolved	dissolve	VERB
admet-497	81	8	,	,	PUNCT
admet-497	81	9	and	and	CCONJ
admet-497	81	10	dissolution	dissolution	ADJ
admet-497	81	11	rate	rate	NOUN
admet-497	81	12	of	of	ADP
admet-497	81	13	cip	cip	NOUN
admet-497	81	14	and	and	CCONJ
admet-497	81	15	cip	cip	NOUN
admet-497	81	16	-	-	PUNCT
admet-497	81	17	r	r	NOUN
admet-497	81	18	in	in	ADP
admet-497	81	19	the	the	DET
admet-497	81	20	dissolution	dissolution	NOUN
admet-497	81	21	experiments	experiment	NOUN
admet-497	81	22	at	at	ADP
admet-497	81	23	different	different	ADJ
admet-497	81	24	ph	ph	ADJ
admet-497	81	25	sectors	sector	NOUN
admet-497	81	26	.	.	PUNCT
admet-497	82	1	ph	ph	ADJ
admet-497	82	2	%	%	NOUN
admet-497	82	3	cip	cip	NOUN
admet-497	82	4	dissolved	dissolve	VERB
admet-497	82	5	dissolution	dissolution	NOUN
admet-497	82	6	rate	rate	NOUN
admet-497	82	7	(	(	PUNCT
admet-497	82	8	mg	mg	PROPN
admet-497	82	9	/	/	SYM
admet-497	82	10	min	min	NOUN
admet-497	82	11	)	)	PUNCT
admet-497	82	12	ciprofloxacin	ciprofloxacin	PROPN
admet-497	82	13	cocrystal	cocrystal	ADJ
admet-497	82	14	ciprofloxacin	ciprofloxacin	PROPN
admet-497	82	15	cocrystal	cocrystal	VERB
admet-497	82	16	2.01	2.01	NUM
admet-497	82	17	±	±	NUM
admet-497	82	18	0.04	0.04	NUM
admet-497	82	19	97.5	97.5	NUM
admet-497	82	20	±	±	NUM
admet-497	82	21	0.1	0.1	NUM
admet-497	82	22	100.0	100.0	NUM
admet-497	82	23	±	±	NUM
admet-497	82	24	0.3	0.3	NUM
admet-497	82	25	1.2	1.2	NUM
admet-497	82	26	±	±	NUM
admet-497	82	27	0.2	0.2	NUM
admet-497	82	28	0.56	0.56	NUM
admet-497	82	29	±	±	NUM
admet-497	82	30	0.06	0.06	NUM
admet-497	82	31	4.01	4.01	NUM
admet-497	82	32	±	±	NUM
admet-497	82	33	0.05	0.05	NUM
admet-497	82	34	41	41	NUM
admet-497	82	35	±	±	NUM
admet-497	82	36	3	3	NUM
admet-497	82	37	98.0	98.0	NUM
admet-497	82	38	±	±	NUM
admet-497	82	39	0.5	0.5	NUM
admet-497	82	40	0.13	0.13	NUM
admet-497	82	41	±	±	NUM
admet-497	82	42	0.01	0.01	NUM
admet-497	82	43	0.23	0.23	NUM
admet-497	82	44	±	±	NUM
admet-497	82	45	0.9	0.9	NUM
admet-497	82	46	5.41	5.41	NUM
admet-497	82	47	±	±	NUM
admet-497	82	48	0.03	0.03	NUM
admet-497	82	49	7.1	7.1	NUM
admet-497	82	50	±	±	NUM
admet-497	82	51	0.7	0.7	NUM
admet-497	82	52	11	11	NUM
admet-497	82	53	±	±	NUM
admet-497	82	54	1	1	NUM
admet-497	82	55	0.017	0.017	NUM
admet-497	82	56	±	±	NUM
admet-497	82	57	0.006	0.006	NUM
admet-497	82	58	0.021	0.021	NUM
admet-497	82	59	±	±	NUM
admet-497	82	60	0.001	0.001	NUM
admet-497	82	61	7.41	7.41	NUM
admet-497	82	62	±	±	NUM
admet-497	82	63	0.08	0.08	NUM
admet-497	82	64	3.7	3.7	NUM
admet-497	82	65	±	±	NUM
admet-497	82	66	0.2	0.2	NUM
admet-497	82	67	6	6	NUM
admet-497	82	68	±	±	NUM
admet-497	82	69	1	1	NUM
admet-497	82	70	0.0033	0.0033	NUM
admet-497	82	71	±	±	NUM
admet-497	82	72	0.0004	0.0004	NUM
admet-497	82	73	0.003	0.003	NUM
admet-497	82	74	±	±	NUM
admet-497	82	75	0.002	0.002	NUM
admet-497	82	76	this	this	PRON
admet-497	82	77	is	be	AUX
admet-497	82	78	the	the	DET
admet-497	82	79	expected	expect	VERB
admet-497	82	80	behavior	behavior	NOUN
admet-497	82	81	according	accord	VERB
admet-497	82	82	to	to	ADP
admet-497	82	83	the	the	DET
admet-497	82	84	ionization	ionization	NOUN
admet-497	82	85	state	state	NOUN
admet-497	82	86	of	of	ADP
admet-497	82	87	cip	cip	NOUN
admet-497	82	88	.	.	PUNCT
admet-497	83	1	the	the	DET
admet-497	83	2	percentage	percentage	NOUN
admet-497	83	3	of	of	ADP
admet-497	83	4	dissolved	dissolve	VERB
admet-497	83	5	cip	cip	NOUN
admet-497	83	6	decreases	decrease	NOUN
admet-497	83	7	dramatically	dramatically	ADV
admet-497	83	8	when	when	SCONJ
admet-497	83	9	changing	change	VERB
admet-497	83	10	ph	ph	NOUN
admet-497	83	11	from	from	ADP
admet-497	83	12	2	2	NUM
admet-497	83	13	to	to	ADP
admet-497	83	14	4	4	NUM
admet-497	83	15	,	,	PUNCT
admet-497	83	16	with	with	ADP
admet-497	83	17	only	only	ADV
admet-497	83	18	41	41	NUM
admet-497	83	19	%	%	NOUN
admet-497	83	20	dissolved	dissolve	VERB
admet-497	83	21	after	after	ADP
admet-497	83	22	30	30	NUM
admet-497	83	23	minutes	minute	NOUN
admet-497	83	24	(	(	PUNCT
admet-497	83	25	table	table	NOUN
admet-497	83	26	1	1	NUM
admet-497	83	27	)	)	PUNCT
admet-497	83	28	,	,	PUNCT
admet-497	83	29	and	and	CCONJ
admet-497	83	30	drops	drop	VERB
admet-497	83	31	to	to	ADP
admet-497	83	32	around	around	ADP
admet-497	83	33	6	6	NUM
admet-497	83	34	and	and	CCONJ
admet-497	83	35	4	4	NUM
admet-497	83	36	%	%	NOUN
admet-497	83	37	at	at	ADP
admet-497	83	38	ph	ph	PROPN
admet-497	83	39	5.5	5.5	NUM
admet-497	83	40	and	and	CCONJ
admet-497	83	41	7.4	7.4	NUM
admet-497	83	42	,	,	PUNCT
admet-497	83	43	respectively	respectively	ADV
admet-497	83	44	.	.	PUNCT
admet-497	84	1	instead	instead	ADV
admet-497	84	2	,	,	PUNCT
admet-497	84	3	the	the	DET
admet-497	84	4	cocrystal	cocrystal	NOUN
admet-497	84	5	dissolves	dissolve	VERB
admet-497	84	6	totally	totally	ADV
admet-497	84	7	after	after	ADP
admet-497	84	8	25	25	NUM
admet-497	84	9	minutes	minute	NOUN
admet-497	84	10	at	at	ADP
admet-497	84	11	ph	ph	PROPN
admet-497	84	12	4	4	NUM
admet-497	84	13	,	,	PUNCT
admet-497	84	14	but	but	CCONJ
admet-497	84	15	its	its	PRON
admet-497	84	16	dissolution	dissolution	NOUN
admet-497	84	17	also	also	ADV
admet-497	84	18	decreases	decrease	VERB
admet-497	84	19	significantly	significantly	ADV
admet-497	84	20	at	at	ADP
admet-497	84	21	ph	ph	PROPN
admet-497	84	22	5.5	5.5	NUM
admet-497	84	23	and	and	CCONJ
admet-497	84	24	7.4	7.4	NUM
admet-497	84	25	(	(	PUNCT
admet-497	84	26	11	11	NUM
admet-497	84	27	and	and	CCONJ
admet-497	84	28	6	6	NUM
admet-497	84	29	%	%	NOUN
admet-497	84	30	of	of	ADP
admet-497	84	31	cip	cip	NOUN
admet-497	84	32	dissolved	dissolve	VERB
admet-497	84	33	)	)	PUNCT
admet-497	84	34	respectively	respectively	ADV
admet-497	84	35	.	.	PUNCT
admet-497	85	1	dissolution	dissolution	NOUN
admet-497	85	2	rate	rate	NOUN
admet-497	85	3	is	be	AUX
admet-497	85	4	directly	directly	ADV
admet-497	85	5	related	relate	VERB
admet-497	85	6	to	to	ADP
admet-497	85	7	the	the	DET
admet-497	85	8	slope	slope	NOUN
admet-497	85	9	of	of	ADP
admet-497	85	10	the	the	DET
admet-497	85	11	dissolution	dissolution	NOUN
admet-497	85	12	curve	curve	NOUN
admet-497	85	13	.	.	PUNCT
admet-497	86	1	comparison	comparison	NOUN
admet-497	86	2	of	of	ADP
admet-497	86	3	dissolution	dissolution	NOUN
admet-497	86	4	rates	rate	NOUN
admet-497	86	5	between	between	ADP
admet-497	86	6	cip	cip	NOUN
admet-497	86	7	and	and	CCONJ
admet-497	86	8	its	its	PRON
admet-497	86	9	cip	cip	NOUN
admet-497	86	10	-	-	PUNCT
admet-497	86	11	r	r	NOUN
admet-497	86	12	evidences	evidence	NOUN
admet-497	86	13	that	that	SCONJ
admet-497	86	14	at	at	ADP
admet-497	86	15	very	very	ADV
admet-497	86	16	low	low	ADJ
admet-497	86	17	ph	ph	ADJ
admet-497	86	18	values	value	NOUN
admet-497	86	19	(	(	PUNCT
admet-497	86	20	ph	ph	NOUN
admet-497	86	21	2	2	NUM
admet-497	86	22	)	)	PUNCT
admet-497	86	23	the	the	DET
admet-497	86	24	dissolution	dissolution	ADJ
admet-497	86	25	rate	rate	NOUN
admet-497	86	26	of	of	ADP
admet-497	86	27	cip	cip	NOUN
admet-497	86	28	is	be	AUX
admet-497	86	29	more	more	ADJ
admet-497	86	30	than	than	ADP
admet-497	86	31	twice	twice	DET
admet-497	86	32	the	the	DET
admet-497	86	33	one	one	NUM
admet-497	86	34	of	of	ADP
admet-497	86	35	the	the	DET
admet-497	86	36	cocrystal	cocrystal	NOUN
admet-497	86	37	,	,	PUNCT
admet-497	86	38	probably	probably	ADV
admet-497	86	39	due	due	ADP
admet-497	86	40	to	to	ADP
admet-497	86	41	the	the	DET
admet-497	86	42	effect	effect	NOUN
admet-497	86	43	of	of	ADP
admet-497	86	44	resorcinol	resorcinol	NOUN
admet-497	86	45	(	(	PUNCT
admet-497	86	46	neutral	neutral	ADJ
admet-497	86	47	at	at	ADP
admet-497	86	48	this	this	DET
admet-497	86	49	ph	ph	NOUN
admet-497	86	50	)	)	PUNCT
admet-497	86	51	,	,	PUNCT
admet-497	86	52	which	which	PRON
admet-497	86	53	slows	slow	VERB
admet-497	86	54	dissolution	dissolution	NOUN
admet-497	86	55	of	of	ADP
admet-497	86	56	cip	cip	NOUN
admet-497	86	57	-	-	PUNCT
admet-497	86	58	r	r	NOUN
admet-497	86	59	down	down	ADV
admet-497	86	60	.	.	PUNCT
admet-497	87	1	however	however	ADV
admet-497	87	2	,	,	PUNCT
admet-497	87	3	as	as	SCONJ
admet-497	87	4	ph	ph	ADJ
admet-497	87	5	increases	increase	NOUN
admet-497	87	6	the	the	DET
admet-497	87	7	dissolution	dissolution	ADJ
admet-497	87	8	rate	rate	NOUN
admet-497	87	9	of	of	ADP
admet-497	87	10	cip	cip	NOUN
admet-497	87	11	and	and	CCONJ
admet-497	87	12	cip	cip	NOUN
admet-497	87	13	-	-	PUNCT
admet-497	87	14	r	r	NOUN
admet-497	87	15	tend	tend	NOUN
admet-497	87	16	to	to	PART
admet-497	87	17	be	be	AUX
admet-497	87	18	the	the	DET
admet-497	87	19	same	same	ADJ
admet-497	87	20	,	,	PUNCT
admet-497	87	21	reaching	reach	VERB
admet-497	87	22	a	a	DET
admet-497	87	23	minimum	minimum	ADJ
admet-497	87	24	value	value	NOUN
admet-497	87	25	of	of	ADP
admet-497	87	26	0.003	0.003	NUM
admet-497	87	27	mg	mg	NOUN
admet-497	87	28	min-1	min-1	NOUN
admet-497	87	29	at	at	ADP
admet-497	87	30	ph	ph	PROPN
admet-497	87	31	7.4	7.4	NUM
admet-497	87	32	.	.	PUNCT
admet-497	88	1	on	on	ADP
admet-497	88	2	the	the	DET
admet-497	88	3	contrary	contrary	NOUN
admet-497	88	4	,	,	PUNCT
admet-497	88	5	the	the	DET
admet-497	88	6	full	full	ADJ
admet-497	88	7	ph	ph	ADJ
admet-497	88	8	experiment	experiment	NOUN
admet-497	88	9	(	(	PUNCT
admet-497	88	10	figure	figure	NOUN
admet-497	88	11	4	4	NUM
admet-497	88	12	)	)	PUNCT
admet-497	88	13	does	do	AUX
admet-497	88	14	not	not	PART
admet-497	88	15	reflect	reflect	VERB
admet-497	88	16	the	the	DET
admet-497	88	17	actual	actual	ADJ
admet-497	88	18	dissolution	dissolution	NOUN
admet-497	88	19	rate	rate	NOUN
admet-497	88	20	of	of	ADP
admet-497	88	21	the	the	DET
admet-497	88	22	compound	compound	NOUN
admet-497	88	23	at	at	ADP
admet-497	88	24	each	each	DET
admet-497	88	25	ph	ph	NOUN
admet-497	88	26	,	,	PUNCT
admet-497	88	27	as	as	SCONJ
admet-497	88	28	both	both	PRON
admet-497	88	29	cip	cip	NOUN
admet-497	88	30	and	and	CCONJ
admet-497	88	31	cip	cip	NOUN
admet-497	88	32	-	-	PUNCT
admet-497	88	33	r	r	NOUN
admet-497	88	34	dissolve	dissolve	NOUN
admet-497	88	35	almost	almost	ADV
admet-497	88	36	totally	totally	ADV
admet-497	88	37	at	at	ADP
admet-497	88	38	the	the	DET
admet-497	88	39	first	first	ADJ
admet-497	88	40	sector	sector	NOUN
admet-497	88	41	(	(	PUNCT
admet-497	88	42	ph	ph	NOUN
admet-497	88	43	2	2	NUM
admet-497	88	44	)	)	PUNCT
admet-497	88	45	.	.	PUNCT
admet-497	89	1	then	then	ADV
admet-497	89	2	solutions	solution	NOUN
admet-497	89	3	stay	stay	VERB
admet-497	89	4	supersaturated	supersaturated	ADJ
admet-497	89	5	at	at	ADP
admet-497	89	6	the	the	DET
admet-497	89	7	following	follow	VERB
admet-497	89	8	ph	ph	ADJ
admet-497	89	9	sectors	sector	NOUN
admet-497	89	10	(	(	PUNCT
admet-497	89	11	4.0	4.0	NUM
admet-497	89	12	,	,	PUNCT
admet-497	89	13	5.5	5.5	NUM
admet-497	89	14	,	,	PUNCT
admet-497	89	15	and	and	CCONJ
admet-497	89	16	7.4	7.4	NUM
admet-497	89	17	)	)	PUNCT
admet-497	89	18	.	.	PUNCT
admet-497	90	1	in	in	ADP
admet-497	90	2	case	case	NOUN
admet-497	90	3	of	of	ADP
admet-497	90	4	cip	cip	NOUN
admet-497	90	5	there	there	PRON
admet-497	90	6	is	be	VERB
admet-497	90	7	evidence	evidence	NOUN
admet-497	90	8	of	of	ADP
admet-497	90	9	precipitation	precipitation	NOUN
admet-497	90	10	at	at	ADP
admet-497	90	11	ph	ph	PROPN
admet-497	90	12	7.4	7.4	NUM
admet-497	90	13	,	,	PUNCT
admet-497	90	14	since	since	SCONJ
admet-497	90	15	the	the	DET
admet-497	90	16	signal	signal	NOUN
admet-497	90	17	falls	fall	VERB
admet-497	90	18	to	to	ADP
admet-497	90	19	zero	zero	NUM
admet-497	90	20	.	.	PUNCT
admet-497	91	1	although	although	SCONJ
admet-497	91	2	this	this	DET
admet-497	91	3	kind	kind	NOUN
admet-497	91	4	of	of	ADP
admet-497	91	5	experiment	experiment	NOUN
admet-497	91	6	does	do	AUX
admet-497	91	7	not	not	PART
admet-497	91	8	allow	allow	VERB
admet-497	91	9	knowing	know	VERB
admet-497	91	10	the	the	DET
admet-497	91	11	dissolution	dissolution	ADJ
admet-497	91	12	behavior	behavior	NOUN
admet-497	91	13	of	of	ADP
admet-497	91	14	the	the	DET
admet-497	91	15	compounds	compound	NOUN
admet-497	91	16	at	at	ADP
admet-497	91	17	a	a	DET
admet-497	91	18	given	give	VERB
admet-497	91	19	ph	ph	NOUN
admet-497	91	20	because	because	SCONJ
admet-497	91	21	each	each	DET
admet-497	91	22	sector	sector	NOUN
admet-497	91	23	is	be	AUX
admet-497	91	24	influenced	influence	VERB
admet-497	91	25	by	by	ADP
admet-497	91	26	the	the	DET
admet-497	91	27	previous	previous	ADJ
admet-497	91	28	one	one	NOUN
admet-497	91	29	,	,	PUNCT
admet-497	91	30	it	it	PRON
admet-497	91	31	can	can	AUX
admet-497	91	32	simulate	simulate	VERB
admet-497	91	33	better	well	ADJ
admet-497	91	34	the	the	DET
admet-497	91	35	processes	process	NOUN
admet-497	91	36	that	that	PRON
admet-497	91	37	compounds	compound	VERB
admet-497	91	38	experience	experience	NOUN
admet-497	91	39	when	when	SCONJ
admet-497	91	40	moving	move	VERB
admet-497	91	41	along	along	ADP
admet-497	91	42	the	the	DET
admet-497	91	43	gastrointestinal	gastrointestinal	ADJ
admet-497	91	44	tract	tract	NOUN
admet-497	91	45	,	,	PUNCT
admet-497	91	46	where	where	SCONJ
admet-497	91	47	different	different	ADJ
admet-497	91	48	ph	ph	ADJ
admet-497	91	49	environments	environment	NOUN
admet-497	91	50	are	be	AUX
admet-497	91	51	encountered	encounter	VERB
admet-497	91	52	.	.	PUNCT
admet-497	92	1	c.	c.	NOUN
admet-497	92	2	ràfols	ràfol	VERB
admet-497	92	3	et	et	PROPN
admet-497	92	4	al	al	PROPN
admet-497	92	5	.	.	PROPN
admet-497	92	6	admet	admet	PROPN
admet-497	92	7	&	&	CCONJ
admet-497	92	8	dmpk	dmpk	PROPN
admet-497	92	9	6(1	6(1	NUM
admet-497	92	10	)	)	PUNCT
admet-497	92	11	(	(	PUNCT
admet-497	92	12	2018	2018	NUM
admet-497	92	13	)	)	PUNCT
admet-497	92	14	61	61	NUM
admet-497	92	15	-	-	SYM
admet-497	92	16	70	70	NUM
admet-497	92	17	66	66	NUM
admet-497	92	18	figure	figure	NOUN
admet-497	92	19	3	3	NUM
admet-497	92	20	:	:	PUNCT
admet-497	92	21	dissolution	dissolution	NOUN
admet-497	92	22	profile	profile	NOUN
admet-497	92	23	at	at	ADP
admet-497	92	24	separate	separate	ADJ
admet-497	92	25	ph	ph	ADJ
admet-497	92	26	sectors	sector	NOUN
admet-497	92	27	for	for	ADP
admet-497	92	28	cip	cip	NOUN
admet-497	92	29	(	(	PUNCT
admet-497	92	30	●	●	NOUN
admet-497	92	31	)	)	PUNCT
admet-497	92	32	and	and	CCONJ
admet-497	92	33	its	its	PRON
admet-497	92	34	cip	cip	NOUN
admet-497	92	35	-	-	PUNCT
admet-497	92	36	r	r	NOUN
admet-497	92	37	(	(	PUNCT
admet-497	92	38	○	○	PROPN
admet-497	92	39	):	):	PUNCT
admet-497	92	40	(	(	PUNCT
admet-497	92	41	a	a	X
admet-497	92	42	)	)	PUNCT
admet-497	92	43	ph	ph	NOUN
admet-497	92	44	=	=	SYM
admet-497	92	45	2	2	NUM
admet-497	92	46	;	;	PUNCT
admet-497	92	47	(	(	PUNCT
admet-497	92	48	b	b	X
admet-497	92	49	)	)	PUNCT
admet-497	92	50	ph	ph	NOUN
admet-497	92	51	=	=	NOUN
admet-497	92	52	4	4	NUM
admet-497	92	53	;	;	PUNCT
admet-497	92	54	(	(	PUNCT
admet-497	92	55	c	c	X
admet-497	92	56	)	)	PUNCT
admet-497	92	57	ph	ph	NOUN
admet-497	92	58	=	=	SYM
admet-497	92	59	5.5	5.5	NUM
admet-497	92	60	;	;	PUNCT
admet-497	92	61	(	(	PUNCT
admet-497	92	62	d	d	X
admet-497	92	63	)	)	PUNCT
admet-497	92	64	ph	ph	NOUN
admet-497	92	65	=	=	NOUN
admet-497	92	66	7.4	7.4	NUM
admet-497	92	67	.	.	PUNCT
admet-497	93	1	x	x	X
admet-497	93	2	-	-	NOUN
admet-497	93	3	ray	ray	NOUN
admet-497	93	4	analysis	analysis	NOUN
admet-497	93	5	of	of	ADP
admet-497	93	6	the	the	DET
admet-497	93	7	surface	surface	NOUN
admet-497	93	8	of	of	ADP
admet-497	93	9	the	the	DET
admet-497	93	10	solid	solid	ADJ
admet-497	93	11	remaining	remain	VERB
admet-497	93	12	in	in	ADP
admet-497	93	13	the	the	DET
admet-497	93	14	disks	disk	NOUN
admet-497	93	15	indicates	indicate	VERB
admet-497	93	16	that	that	SCONJ
admet-497	93	17	approximately	approximately	ADV
admet-497	93	18	50	50	NUM
admet-497	93	19	%	%	NOUN
admet-497	93	20	of	of	ADP
admet-497	93	21	the	the	DET
admet-497	93	22	solid	solid	ADJ
admet-497	93	23	remaining	remain	VERB
admet-497	93	24	in	in	ADP
admet-497	93	25	cip	cip	NOUN
admet-497	93	26	tablets	tablet	NOUN
admet-497	93	27	is	be	AUX
admet-497	93	28	transformed	transform	VERB
admet-497	93	29	to	to	ADP
admet-497	93	30	cip·3h2o	cip·3h2o	NOUN
admet-497	93	31	,	,	PUNCT
admet-497	93	32	whatever	whatever	PRON
admet-497	93	33	the	the	DET
admet-497	93	34	working	work	VERB
admet-497	93	35	ph	ph	PROPN
admet-497	93	36	.	.	PUNCT
admet-497	94	1	meanwhile	meanwhile	ADV
admet-497	94	2	,	,	PUNCT
admet-497	94	3	the	the	DET
admet-497	94	4	surface	surface	NOUN
admet-497	94	5	of	of	ADP
admet-497	94	6	the	the	DET
admet-497	94	7	cocrystal	cocrystal	ADJ
admet-497	94	8	tablets	tablet	NOUN
admet-497	94	9	contain	contain	VERB
admet-497	94	10	about	about	ADV
admet-497	94	11	90	90	NUM
admet-497	94	12	%	%	NOUN
admet-497	94	13	of	of	ADP
admet-497	94	14	the	the	DET
admet-497	94	15	original	original	ADJ
admet-497	94	16	cocrystal	cocrystal	NOUN
admet-497	94	17	,	,	PUNCT
admet-497	94	18	and	and	CCONJ
admet-497	94	19	only	only	ADV
admet-497	94	20	10	10	NUM
admet-497	94	21	%	%	NOUN
admet-497	94	22	of	of	ADP
admet-497	94	23	cip·3h2o	cip·3h2o	NOUN
admet-497	94	24	.	.	PUNCT
admet-497	95	1	these	these	DET
admet-497	95	2	transformations	transformation	NOUN
admet-497	95	3	in	in	ADP
admet-497	95	4	the	the	DET
admet-497	95	5	tablet	tablet	NOUN
admet-497	95	6	surface	surface	NOUN
admet-497	95	7	may	may	AUX
admet-497	95	8	modify	modify	VERB
admet-497	95	9	,	,	PUNCT
admet-497	95	10	to	to	ADP
admet-497	95	11	some	some	DET
admet-497	95	12	extent	extent	NOUN
admet-497	95	13	,	,	PUNCT
admet-497	95	14	the	the	DET
admet-497	95	15	dissolution	dissolution	NOUN
admet-497	95	16	of	of	ADP
admet-497	95	17	the	the	DET
admet-497	95	18	compounds	compound	NOUN
admet-497	95	19	,	,	PUNCT
admet-497	95	20	especially	especially	ADV
admet-497	95	21	for	for	ADP
admet-497	95	22	cip	cip	NOUN
admet-497	95	23	where	where	SCONJ
admet-497	95	24	the	the	DET
admet-497	95	25	percentage	percentage	NOUN
admet-497	95	26	of	of	ADP
admet-497	95	27	transformation	transformation	NOUN
admet-497	95	28	to	to	ADP
admet-497	95	29	the	the	DET
admet-497	95	30	trihydrated	trihydrate	VERB
admet-497	95	31	form	form	NOUN
admet-497	95	32	is	be	AUX
admet-497	95	33	higher	high	ADJ
admet-497	95	34	.	.	PUNCT
admet-497	96	1	in	in	ADP
admet-497	96	2	general	general	ADJ
admet-497	96	3	,	,	PUNCT
admet-497	96	4	the	the	DET
admet-497	96	5	appearance	appearance	NOUN
admet-497	96	6	of	of	ADP
admet-497	96	7	hydrated	hydrated	ADJ
admet-497	96	8	forms	form	NOUN
admet-497	96	9	slows	slow	VERB
admet-497	96	10	the	the	DET
admet-497	96	11	dissolution	dissolution	NOUN
admet-497	96	12	process	process	NOUN
admet-497	96	13	down	down	ADP
admet-497	96	14	because	because	SCONJ
admet-497	96	15	of	of	ADP
admet-497	96	16	the	the	DET
admet-497	96	17	lower	low	ADJ
admet-497	96	18	ion	ion	NOUN
admet-497	96	19	-	-	PUNCT
admet-497	96	20	dipole	dipole	NOUN
admet-497	96	21	interaction	interaction	NOUN
admet-497	96	22	energy	energy	NOUN
admet-497	96	23	liberated	liberate	VERB
admet-497	96	24	on	on	ADP
admet-497	96	25	its	its	PRON
admet-497	96	26	dissolution	dissolution	NOUN
admet-497	97	1	[	[	X
admet-497	97	2	21	21	NUM
admet-497	97	3	]	]	PUNCT
admet-497	97	4	.	.	PUNCT
admet-497	98	1	only	only	ADV
admet-497	98	2	at	at	ADP
admet-497	98	3	ph	ph	PROPN
admet-497	98	4	4.0	4.0	NUM
admet-497	98	5	a	a	DET
admet-497	98	6	slightly	slightly	ADJ
admet-497	98	7	decrease	decrease	NOUN
admet-497	98	8	in	in	ADP
admet-497	98	9	the	the	DET
admet-497	98	10	dissolution	dissolution	NOUN
admet-497	98	11	rate	rate	NOUN
admet-497	98	12	of	of	ADP
admet-497	98	13	cip	cip	NOUN
admet-497	98	14	compared	compare	VERB
admet-497	98	15	to	to	ADP
admet-497	98	16	cip	cip	NOUN
admet-497	98	17	-	-	PUNCT
admet-497	98	18	r	r	NOUN
admet-497	98	19	was	be	AUX
admet-497	98	20	observed	observe	VERB
admet-497	98	21	.	.	PUNCT
admet-497	99	1	nevertheless	nevertheless	ADV
admet-497	99	2	,	,	PUNCT
admet-497	99	3	there	there	PRON
admet-497	99	4	are	be	VERB
admet-497	99	5	not	not	PART
admet-497	99	6	enough	enough	ADJ
admet-497	99	7	evidences	evidence	NOUN
admet-497	99	8	to	to	PART
admet-497	99	9	know	know	VERB
admet-497	99	10	the	the	DET
admet-497	99	11	reasons	reason	NOUN
admet-497	99	12	behind	behind	ADP
admet-497	99	13	cip	cip	NOUN
admet-497	99	14	-	-	PUNCT
admet-497	99	15	r	r	NOUN
admet-497	99	16	higher	high	ADJ
admet-497	99	17	dissolution	dissolution	NOUN
admet-497	99	18	rate	rate	NOUN
admet-497	99	19	.	.	PUNCT
admet-497	100	1	on	on	ADP
admet-497	100	2	one	one	NUM
admet-497	100	3	hand	hand	NOUN
admet-497	100	4	the	the	DET
admet-497	100	5	cocrystal	cocrystal	NOUN
admet-497	100	6	itself	itself	PRON
admet-497	100	7	could	could	AUX
admet-497	100	8	dissolve	dissolve	VERB
admet-497	100	9	faster	fast	ADV
admet-497	100	10	than	than	ADP
admet-497	100	11	the	the	DET
admet-497	100	12	pure	pure	ADJ
admet-497	100	13	api	api	NOUN
admet-497	100	14	,	,	PUNCT
admet-497	100	15	and	and	CCONJ
admet-497	100	16	on	on	ADP
admet-497	100	17	the	the	DET
admet-497	100	18	other	other	ADJ
admet-497	100	19	hand	hand	NOUN
admet-497	100	20	there	there	PRON
admet-497	100	21	could	could	AUX
admet-497	100	22	be	be	AUX
admet-497	100	23	a	a	DET
admet-497	100	24	decrease	decrease	NOUN
admet-497	100	25	in	in	ADP
admet-497	100	26	the	the	DET
admet-497	100	27	dissolution	dissolution	NOUN
admet-497	100	28	of	of	ADP
admet-497	100	29	the	the	DET
admet-497	100	30	api	api	NOUN
admet-497	100	31	caused	cause	VERB
admet-497	100	32	by	by	ADP
admet-497	100	33	the	the	DET
admet-497	100	34	transformation	transformation	NOUN
admet-497	100	35	into	into	ADP
admet-497	100	36	cip·3h2o	cip·3h2o	NOUN
admet-497	100	37	on	on	ADP
admet-497	100	38	the	the	DET
admet-497	100	39	surface	surface	NOUN
admet-497	100	40	of	of	ADP
admet-497	100	41	the	the	DET
admet-497	100	42	tablet	tablet	NOUN
admet-497	100	43	.	.	PUNCT
admet-497	101	1	results	result	NOUN
admet-497	101	2	of	of	ADP
admet-497	101	3	dissolution	dissolution	NOUN
admet-497	101	4	rate	rate	NOUN
admet-497	101	5	determinations	determination	NOUN
admet-497	101	6	in	in	ADP
admet-497	101	7	simulated	simulated	ADJ
admet-497	101	8	gastrointestinal	gastrointestinal	ADJ
admet-497	101	9	media	medium	NOUN
admet-497	101	10	are	be	AUX
admet-497	101	11	shown	show	VERB
admet-497	101	12	in	in	ADP
admet-497	101	13	table	table	NOUN
admet-497	101	14	2	2	NUM
admet-497	101	15	and	and	CCONJ
admet-497	101	16	figure	figure	VERB
admet-497	101	17	5	5	NUM
admet-497	101	18	.	.	PUNCT
admet-497	102	1	experiments	experiment	NOUN
admet-497	102	2	have	have	AUX
admet-497	102	3	been	be	AUX
admet-497	102	4	done	do	VERB
admet-497	102	5	not	not	PART
admet-497	102	6	only	only	ADV
admet-497	102	7	in	in	ADP
admet-497	102	8	the	the	DET
admet-497	102	9	two	two	NUM
admet-497	102	10	gastrointestinal	gastrointestinal	ADJ
admet-497	102	11	fluids	fluid	NOUN
admet-497	102	12	,	,	PUNCT
admet-497	102	13	but	but	CCONJ
admet-497	102	14	also	also	ADV
admet-497	102	15	in	in	ADP
admet-497	102	16	acetate	acetate	NOUN
admet-497	102	17	/	/	SYM
admet-497	102	18	phosphate	phosphate	NOUN
admet-497	102	19	buffer	buffer	NOUN
admet-497	102	20	at	at	ADP
admet-497	102	21	the	the	DET
admet-497	102	22	same	same	ADJ
admet-497	102	23	ph	ph	NOUN
admet-497	102	24	.	.	PUNCT
admet-497	103	1	in	in	ADP
admet-497	103	2	this	this	DET
admet-497	103	3	way	way	NOUN
admet-497	103	4	it	it	PRON
admet-497	103	5	is	be	AUX
admet-497	103	6	possible	possible	ADJ
admet-497	103	7	to	to	PART
admet-497	103	8	evaluate	evaluate	VERB
admet-497	103	9	the	the	DET
admet-497	103	10	real	real	ADJ
admet-497	103	11	effect	effect	NOUN
admet-497	103	12	of	of	ADP
admet-497	103	13	the	the	DET
admet-497	103	14	gastric	gastric	ADJ
admet-497	103	15	media	medium	NOUN
admet-497	103	16	components	component	NOUN
admet-497	103	17	(	(	PUNCT
admet-497	103	18	mainly	mainly	ADV
admet-497	103	19	bile	bile	NOUN
admet-497	103	20	salts	salt	NOUN
admet-497	103	21	and	and	CCONJ
admet-497	103	22	lecithin	lecithin	NOUN
admet-497	103	23	)	)	PUNCT
admet-497	103	24	to	to	ADP
admet-497	103	25	dissolution	dissolution	ADJ
admet-497	103	26	behavior	behavior	NOUN
admet-497	103	27	of	of	ADP
admet-497	103	28	the	the	DET
admet-497	103	29	compounds	compound	NOUN
admet-497	103	30	,	,	PUNCT
admet-497	103	31	independently	independently	ADV
admet-497	103	32	of	of	ADP
admet-497	103	33	ph	ph	PROPN
admet-497	103	34	.	.	PROPN
admet-497	103	35	table	table	NOUN
admet-497	103	36	2	2	NUM
admet-497	103	37	and	and	CCONJ
admet-497	103	38	figure	figure	VERB
admet-497	103	39	5a	5a	NUM
admet-497	103	40	show	show	VERB
admet-497	103	41	a	a	DET
admet-497	103	42	different	different	ADJ
admet-497	103	43	behavior	behavior	NOUN
admet-497	103	44	of	of	ADP
admet-497	103	45	cip	cip	PROPN
admet-497	103	46	and	and	CCONJ
admet-497	103	47	cip	cip	NOUN
admet-497	103	48	-	-	PUNCT
admet-497	103	49	r	r	NOUN
admet-497	103	50	at	at	ADP
admet-497	103	51	ph	ph	NOUN
admet-497	103	52	5	5	NUM
admet-497	103	53	.	.	PUNCT
admet-497	104	1	the	the	DET
admet-497	104	2	cocrystal	cocrystal	PROPN
admet-497	104	3	dissolves	dissolve	VERB
admet-497	104	4	faster	fast	ADV
admet-497	104	5	than	than	ADP
admet-497	104	6	the	the	DET
admet-497	104	7	pure	pure	ADJ
admet-497	104	8	api	api	NOUN
admet-497	104	9	.	.	PUNCT
admet-497	105	1	however	however	ADV
admet-497	105	2	the	the	DET
admet-497	105	3	differences	difference	NOUN
admet-497	105	4	can	can	AUX
admet-497	105	5	not	not	PART
admet-497	105	6	be	be	AUX
admet-497	105	7	attributed	attribute	VERB
admet-497	105	8	to	to	ADP
admet-497	105	9	fessif	fessif	PROPN
admet-497	105	10	components	component	NOUN
admet-497	105	11	since	since	SCONJ
admet-497	105	12	in	in	ADP
admet-497	105	13	both	both	DET
admet-497	105	14	cases	case	NOUN
admet-497	105	15	dissolution	dissolution	ADJ
admet-497	105	16	rates	rate	NOUN
admet-497	105	17	are	be	AUX
admet-497	105	18	practically	practically	ADV
admet-497	105	19	the	the	DET
admet-497	105	20	same	same	ADJ
admet-497	105	21	in	in	ADP
admet-497	105	22	fessif	fessif	NOUN
admet-497	105	23	and	and	CCONJ
admet-497	105	24	in	in	ADP
admet-497	105	25	the	the	DET
admet-497	105	26	plain	plain	ADJ
admet-497	105	27	buffer	buffer	NOUN
admet-497	105	28	.	.	PUNCT
admet-497	106	1	again	again	ADV
admet-497	106	2	,	,	PUNCT
admet-497	106	3	the	the	DET
admet-497	106	4	reason	reason	NOUN
admet-497	106	5	can	can	AUX
admet-497	106	6	be	be	AUX
admet-497	106	7	due	due	ADJ
admet-497	106	8	to	to	ADP
admet-497	106	9	a	a	DET
admet-497	106	10	faster	fast	ADJ
admet-497	106	11	dissolution	dissolution	NOUN
admet-497	106	12	of	of	ADP
admet-497	106	13	the	the	DET
admet-497	106	14	cocrystal	cocrystal	NOUN
admet-497	106	15	,	,	PUNCT
admet-497	106	16	or	or	CCONJ
admet-497	106	17	due	due	ADP
admet-497	106	18	to	to	ADP
admet-497	106	19	the	the	DET
admet-497	106	20	transformation	transformation	NOUN
admet-497	106	21	of	of	ADP
admet-497	106	22	the	the	DET
admet-497	106	23	api	api	NOUN
admet-497	106	24	into	into	ADP
admet-497	106	25	the	the	DET
admet-497	106	26	trihydrated	trihydrate	VERB
admet-497	106	27	form	form	NOUN
admet-497	106	28	,	,	PUNCT
admet-497	106	29	as	as	SCONJ
admet-497	106	30	stated	state	VERB
admet-497	106	31	by	by	ADP
admet-497	106	32	pxrd	pxrd	NOUN
admet-497	106	33	.	.	PUNCT
admet-497	107	1	in	in	ADP
admet-497	107	2	fact	fact	NOUN
admet-497	107	3	,	,	PUNCT
admet-497	107	4	x	x	ADJ
admet-497	107	5	-	-	NOUN
admet-497	107	6	ray	ray	NOUN
admet-497	107	7	analysis	analysis	NOUN
admet-497	107	8	of	of	ADP
admet-497	107	9	the	the	DET
admet-497	107	10	remaining	remain	VERB
admet-497	107	11	tablets	tablet	NOUN
admet-497	107	12	indicated	indicate	VERB
admet-497	107	13	that	that	SCONJ
admet-497	107	14	the	the	DET
admet-497	107	15	surface	surface	NOUN
admet-497	107	16	of	of	ADP
admet-497	107	17	the	the	DET
admet-497	107	18	cocrystals	cocrystal	NOUN
admet-497	107	19	were	be	AUX
admet-497	107	20	hardly	hardly	ADV
admet-497	107	21	modified	modify	VERB
admet-497	107	22	(	(	PUNCT
admet-497	107	23	90	90	NUM
admet-497	107	24	%	%	NOUN
admet-497	107	25	cocrystal	cocrystal	ADJ
admet-497	107	26	and	and	CCONJ
admet-497	107	27	10	10	NUM
admet-497	107	28	%	%	NOUN
admet-497	107	29	cip·3h2o	cip·3h2o	NOUN
admet-497	107	30	)	)	PUNCT
admet-497	107	31	in	in	ADP
admet-497	107	32	these	these	DET
admet-497	107	33	two	two	NUM
admet-497	107	34	media	medium	NOUN
admet-497	107	35	,	,	PUNCT
admet-497	107	36	whereas	whereas	SCONJ
admet-497	107	37	the	the	DET
admet-497	107	38	tables	table	NOUN
admet-497	107	39	of	of	ADP
admet-497	107	40	cip	cip	NOUN
admet-497	107	41	alone	alone	ADV
admet-497	107	42	were	be	AUX
admet-497	107	43	strongly	strongly	ADV
admet-497	107	44	modified	modify	VERB
admet-497	107	45	(	(	PUNCT
admet-497	107	46	10	10	NUM
admet-497	107	47	%	%	NOUN
admet-497	107	48	cip	cip	NOUN
admet-497	107	49	and	and	CCONJ
admet-497	107	50	90	90	NUM
admet-497	107	51	%	%	NOUN
admet-497	107	52	cip·3h2o	cip·3h2o	NOUN
admet-497	107	53	)	)	PUNCT
admet-497	107	54	.	.	PUNCT
admet-497	108	1	as	as	SCONJ
admet-497	108	2	expected	expect	VERB
admet-497	108	3	,	,	PUNCT
admet-497	108	4	admet	admet	PROPN
admet-497	108	5	&	&	CCONJ
admet-497	108	6	dmpk	dmpk	PROPN
admet-497	108	7	6(1	6(1	NUM
admet-497	108	8	)	)	PUNCT
admet-497	108	9	(	(	PUNCT
admet-497	108	10	2018	2018	NUM
admet-497	108	11	)	)	PUNCT
admet-497	108	12	61	61	NUM
admet-497	108	13	-	-	SYM
admet-497	108	14	70	70	NUM
admet-497	108	15	dissolution	dissolution	NOUN
admet-497	108	16	rates	rate	NOUN
admet-497	108	17	of	of	ADP
admet-497	108	18	ciprofloxacin	ciprofloxacin	PROPN
admet-497	108	19	and	and	CCONJ
admet-497	108	20	its	its	PRON
admet-497	108	21	cocrystal	cocrystal	NOUN
admet-497	108	22	with	with	ADP
admet-497	108	23	resorcinol	resorcinol	NOUN
admet-497	108	24	doi	doi	NOUN
admet-497	108	25	:	:	PUNCT
admet-497	108	26	10.5599	10.5599	NUM
admet-497	108	27	/	/	SYM
admet-497	108	28	admet.6.1.497	admet.6.1.497	PROPN
admet-497	108	29	67	67	NUM
admet-497	108	30	dissolution	dissolution	NOUN
admet-497	108	31	rate	rate	NOUN
admet-497	108	32	values	value	NOUN
admet-497	108	33	of	of	ADP
admet-497	108	34	cip	cip	NOUN
admet-497	108	35	and	and	CCONJ
admet-497	108	36	cip	cip	NOUN
admet-497	108	37	-	-	PUNCT
admet-497	108	38	r	r	NOUN
admet-497	108	39	at	at	ADP
admet-497	108	40	ph	ph	ADJ
admet-497	108	41	5	5	NUM
admet-497	108	42	are	be	AUX
admet-497	108	43	in	in	ADP
admet-497	108	44	between	between	ADP
admet-497	108	45	the	the	DET
admet-497	108	46	ones	one	NOUN
admet-497	108	47	determined	determine	VERB
admet-497	108	48	at	at	ADP
admet-497	108	49	ph	ph	PROPN
admet-497	108	50	4.0	4.0	NUM
admet-497	108	51	and	and	CCONJ
admet-497	108	52	5.5	5.5	NUM
admet-497	108	53	(	(	PUNCT
admet-497	108	54	table	table	NOUN
admet-497	108	55	1	1	NUM
admet-497	108	56	)	)	PUNCT
admet-497	108	57	.	.	PUNCT
admet-497	109	1	figure	figure	VERB
admet-497	109	2	4	4	NUM
admet-497	109	3	:	:	PUNCT
admet-497	109	4	full	full	ADJ
admet-497	109	5	ph	ph	ADJ
admet-497	109	6	dissolution	dissolution	NOUN
admet-497	109	7	experiment	experiment	NOUN
admet-497	109	8	for	for	ADP
admet-497	109	9	cip	cip	NOUN
admet-497	109	10	(	(	PUNCT
admet-497	109	11	●	●	NOUN
admet-497	109	12	)	)	PUNCT
admet-497	109	13	and	and	CCONJ
admet-497	109	14	cip	cip	NOUN
admet-497	109	15	-	-	PUNCT
admet-497	109	16	r	r	NOUN
admet-497	109	17	(	(	PUNCT
admet-497	109	18	○	○	PROPN
admet-497	109	19	)	)	PUNCT
admet-497	109	20	.	.	PUNCT
admet-497	110	1	results	result	NOUN
admet-497	110	2	in	in	ADP
admet-497	110	3	fassif	fassif	NOUN
admet-497	110	4	and	and	CCONJ
admet-497	110	5	the	the	DET
admet-497	110	6	corresponding	corresponding	ADJ
admet-497	110	7	plain	plain	ADJ
admet-497	110	8	buffer	buffer	NOUN
admet-497	110	9	(	(	PUNCT
admet-497	110	10	ph	ph	NOUN
admet-497	110	11	6.4	6.4	NUM
admet-497	110	12	)	)	PUNCT
admet-497	110	13	(	(	PUNCT
admet-497	110	14	figure	figure	NOUN
admet-497	110	15	3b	3b	NUM
admet-497	110	16	)	)	PUNCT
admet-497	110	17	show	show	VERB
admet-497	110	18	that	that	SCONJ
admet-497	110	19	either	either	CCONJ
admet-497	110	20	dissolution	dissolution	ADJ
admet-497	110	21	rate	rate	NOUN
admet-497	110	22	or	or	CCONJ
admet-497	110	23	percentage	percentage	NOUN
admet-497	110	24	of	of	ADP
admet-497	110	25	cip	cip	NOUN
admet-497	110	26	dissolved	dissolve	VERB
admet-497	110	27	for	for	ADP
admet-497	110	28	cip	cip	NOUN
admet-497	110	29	and	and	CCONJ
admet-497	110	30	cip	cip	NOUN
admet-497	110	31	-	-	PUNCT
admet-497	110	32	r	r	NOUN
admet-497	110	33	are	be	AUX
admet-497	110	34	equivalent	equivalent	ADJ
admet-497	110	35	.	.	PUNCT
admet-497	111	1	again	again	ADV
admet-497	111	2	,	,	PUNCT
admet-497	111	3	these	these	DET
admet-497	111	4	results	result	NOUN
admet-497	111	5	are	be	AUX
admet-497	111	6	located	locate	VERB
admet-497	111	7	in	in	ADP
admet-497	111	8	between	between	ADP
admet-497	111	9	the	the	DET
admet-497	111	10	results	result	NOUN
admet-497	111	11	at	at	ADP
admet-497	111	12	ph	ph	PROPN
admet-497	111	13	5.5	5.5	NUM
admet-497	111	14	and	and	CCONJ
admet-497	111	15	7.4	7.4	NUM
admet-497	111	16	in	in	ADP
admet-497	111	17	table	table	NOUN
admet-497	111	18	1	1	NUM
admet-497	111	19	for	for	ADP
admet-497	111	20	both	both	DET
admet-497	111	21	compounds	compound	NOUN
admet-497	111	22	.	.	PUNCT
admet-497	112	1	thus	thus	ADV
admet-497	112	2	,	,	PUNCT
admet-497	112	3	apparently	apparently	ADV
admet-497	112	4	there	there	PRON
admet-497	112	5	is	be	VERB
admet-497	112	6	no	no	DET
admet-497	112	7	effect	effect	NOUN
admet-497	112	8	of	of	ADP
admet-497	112	9	fassif	fassif	NOUN
admet-497	112	10	or	or	CCONJ
admet-497	112	11	fessif	fessif	VERB
admet-497	112	12	components	component	NOUN
admet-497	112	13	on	on	ADP
admet-497	112	14	the	the	DET
admet-497	112	15	dissolution	dissolution	NOUN
admet-497	112	16	rate	rate	NOUN
admet-497	112	17	;	;	PUNCT
admet-497	112	18	only	only	ADV
admet-497	112	19	the	the	DET
admet-497	112	20	ionization	ionization	NOUN
admet-497	112	21	degree	degree	NOUN
admet-497	112	22	seems	seem	VERB
admet-497	112	23	to	to	PART
admet-497	112	24	play	play	VERB
admet-497	112	25	an	an	DET
admet-497	112	26	important	important	ADJ
admet-497	112	27	role	role	NOUN
admet-497	112	28	in	in	ADP
admet-497	112	29	their	their	PRON
admet-497	112	30	dissolution	dissolution	NOUN
admet-497	112	31	.	.	PUNCT
admet-497	113	1	the	the	DET
admet-497	113	2	zwitterionic	zwitterionic	ADJ
admet-497	113	3	nature	nature	NOUN
admet-497	113	4	of	of	ADP
admet-497	113	5	cip	cip	NOUN
admet-497	113	6	may	may	AUX
admet-497	113	7	be	be	AUX
admet-497	113	8	one	one	NUM
admet-497	113	9	of	of	ADP
admet-497	113	10	the	the	DET
admet-497	113	11	reasons	reason	NOUN
admet-497	113	12	that	that	PRON
admet-497	113	13	gastrointestinal	gastrointestinal	ADJ
admet-497	113	14	simulated	simulate	VERB
admet-497	113	15	fluids	fluid	NOUN
admet-497	113	16	have	have	VERB
admet-497	113	17	no	no	DET
admet-497	113	18	solubilizing	solubilize	VERB
admet-497	113	19	effect	effect	NOUN
admet-497	113	20	on	on	ADP
admet-497	113	21	cip	cip	NOUN
admet-497	113	22	,	,	PUNCT
admet-497	113	23	since	since	SCONJ
admet-497	113	24	other	other	ADJ
admet-497	113	25	studies	study	NOUN
admet-497	113	26	[	[	X
admet-497	113	27	22	22	NUM
admet-497	113	28	-	-	SYM
admet-497	113	29	24	24	NUM
admet-497	113	30	]	]	PUNCT
admet-497	113	31	point	point	NOUN
admet-497	113	32	out	out	ADP
admet-497	113	33	that	that	SCONJ
admet-497	113	34	the	the	DET
admet-497	113	35	micelles	micelle	NOUN
admet-497	113	36	formed	form	VERB
admet-497	113	37	in	in	ADP
admet-497	113	38	these	these	DET
admet-497	113	39	fluids	fluid	NOUN
admet-497	113	40	have	have	AUX
admet-497	113	41	negatively	negatively	ADV
admet-497	113	42	charged	charge	VERB
admet-497	113	43	surface	surface	NOUN
admet-497	113	44	,	,	PUNCT
admet-497	113	45	what	what	PRON
admet-497	113	46	means	mean	VERB
admet-497	113	47	attraction	attraction	NOUN
admet-497	113	48	for	for	ADP
admet-497	113	49	cations	cation	NOUN
admet-497	113	50	,	,	PUNCT
admet-497	113	51	repulsion	repulsion	NOUN
admet-497	113	52	for	for	ADP
admet-497	113	53	anions	anion	NOUN
admet-497	113	54	,	,	PUNCT
admet-497	113	55	and	and	CCONJ
admet-497	113	56	may	may	AUX
admet-497	113	57	be	be	AUX
admet-497	113	58	no	no	DET
admet-497	113	59	effect	effect	NOUN
admet-497	113	60	on	on	ADP
admet-497	113	61	zwitterions	zwitterion	NOUN
admet-497	113	62	.	.	PUNCT
admet-497	113	63	table	table	NOUN
admet-497	113	64	2	2	NUM
admet-497	113	65	:	:	PUNCT
admet-497	113	66	percentage	percentage	NOUN
admet-497	113	67	of	of	ADP
admet-497	113	68	cip	cip	NOUN
admet-497	113	69	dissolved	dissolve	VERB
admet-497	113	70	,	,	PUNCT
admet-497	113	71	and	and	CCONJ
admet-497	113	72	dissolution	dissolution	ADJ
admet-497	113	73	rate	rate	NOUN
admet-497	113	74	of	of	ADP
admet-497	113	75	cip	cip	NOUN
admet-497	113	76	and	and	CCONJ
admet-497	113	77	cip	cip	NOUN
admet-497	113	78	-	-	PUNCT
admet-497	113	79	r	r	NOUN
admet-497	113	80	;	;	PUNCT
admet-497	113	81	in	in	ADP
admet-497	113	82	fessif	fessif	NOUN
admet-497	113	83	,	,	PUNCT
admet-497	113	84	fassif	fassif	NOUN
admet-497	113	85	and	and	CCONJ
admet-497	113	86	in	in	ADP
admet-497	113	87	standard	standard	ADJ
admet-497	113	88	buffer	buffer	NOUN
admet-497	113	89	at	at	ADP
admet-497	113	90	the	the	DET
admet-497	113	91	same	same	ADJ
admet-497	113	92	ph	ph	NOUN
admet-497	113	93	(	(	PUNCT
admet-497	113	94	5.0	5.0	NUM
admet-497	113	95	and	and	CCONJ
admet-497	113	96	6.5	6.5	NUM
admet-497	113	97	respectively	respectively	ADV
admet-497	113	98	)	)	PUNCT
admet-497	113	99	.	.	PUNCT
admet-497	114	1	ph	ph	PROPN
admet-497	114	2	%	%	NOUN
admet-497	114	3	cip	cip	NOUN
admet-497	114	4	dissolved	dissolve	VERB
admet-497	114	5	dissolution	dissolution	NOUN
admet-497	114	6	rate	rate	NOUN
admet-497	114	7	(	(	PUNCT
admet-497	114	8	mg	mg	PROPN
admet-497	114	9	/	/	SYM
admet-497	114	10	min	min	NOUN
admet-497	114	11	)	)	PUNCT
admet-497	114	12	ciprofloxacin	ciprofloxacin	PROPN
admet-497	114	13	cocrystal	cocrystal	ADJ
admet-497	114	14	ciprofloxacin	ciprofloxacin	PROPN
admet-497	114	15	cocrystal	cocrystal	ADJ
admet-497	114	16	fessif	fessif	PROPN
admet-497	114	17	(	(	PUNCT
admet-497	114	18	ph	ph	PROPN
admet-497	114	19	=	=	SYM
admet-497	114	20	4.94	4.94	NUM
admet-497	114	21	±	±	NUM
admet-497	114	22	0.05	0.05	NUM
admet-497	114	23	)	)	PUNCT
admet-497	114	24	23	23	NUM
admet-497	114	25	±	±	NUM
admet-497	114	26	4	4	NUM
admet-497	114	27	94	94	NUM
admet-497	114	28	±	±	NUM
admet-497	114	29	2	2	NUM
admet-497	114	30	0.07	0.07	NUM
admet-497	114	31	±	±	NUM
admet-497	114	32	0.01	0.01	NUM
admet-497	114	33	0.25	0.25	NUM
admet-497	114	34	±	±	NUM
admet-497	114	35	0.04	0.04	NUM
admet-497	114	36	buffer	buffer	NOUN
admet-497	114	37	ph	ph	NOUN
admet-497	114	38	=	=	SYM
admet-497	114	39	4.94	4.94	NUM
admet-497	114	40	±	±	NUM
admet-497	114	41	0.05	0.05	NUM
admet-497	114	42	26	26	NUM
admet-497	114	43	±	±	NUM
admet-497	114	44	1	1	NUM
admet-497	114	45	105	105	NUM
admet-497	114	46	±	±	NUM
admet-497	114	47	4	4	NUM
admet-497	114	48	0.067	0.067	NUM
admet-497	114	49	±	±	NUM
admet-497	114	50	0.001	0.001	NUM
admet-497	114	51	0.29	0.29	NUM
admet-497	114	52	±	±	NUM
admet-497	114	53	0.1	0.1	NUM
admet-497	114	54	fassif	fassif	NOUN
admet-497	114	55	(	(	PUNCT
admet-497	114	56	ph	ph	NOUN
admet-497	114	57	=	=	SYM
admet-497	114	58	6.37	6.37	NUM
admet-497	114	59	±	±	NUM
admet-497	114	60	0.05	0.05	NUM
admet-497	114	61	)	)	PUNCT
admet-497	114	62	1.7	1.7	NUM
admet-497	114	63	±	±	NUM
admet-497	114	64	0.1	0.1	NUM
admet-497	114	65	2.5	2.5	NUM
admet-497	114	66	±	±	NUM
admet-497	114	67	0.5	0.5	NUM
admet-497	114	68	0.0038±	0.0038±	PROPN
admet-497	114	69	0.0004	0.0004	NUM
admet-497	114	70	0.005	0.005	NUM
admet-497	114	71	±	±	NUM
admet-497	114	72	0.002	0.002	NUM
admet-497	114	73	buffer	buffer	NOUN
admet-497	114	74	ph	ph	NOUN
admet-497	114	75	=	=	SYM
admet-497	114	76	6.43	6.43	NUM
admet-497	114	77	±	±	NUM
admet-497	114	78	0.04	0.04	NUM
admet-497	114	79	2.2	2.2	NUM
admet-497	114	80	±	±	NUM
admet-497	114	81	0.2	0.2	NUM
admet-497	114	82	2.10	2.10	NUM
admet-497	114	83	±	±	NUM
admet-497	114	84	0.07	0.07	NUM
admet-497	114	85	0.005	0.005	NUM
admet-497	114	86	±	±	NUM
admet-497	114	87	0.001	0.001	NUM
admet-497	114	88	0.003	0.003	NUM
admet-497	114	89	±	±	NOUN
admet-497	114	90	0.001	0.001	NUM
admet-497	114	91	conclusions	conclusion	NOUN
admet-497	114	92	dissolution	dissolution	NOUN
admet-497	114	93	rate	rate	NOUN
admet-497	114	94	of	of	ADP
admet-497	114	95	ciprofloxacin	ciprofloxacin	PROPN
admet-497	114	96	and	and	CCONJ
admet-497	114	97	its	its	PRON
admet-497	114	98	cocrystal	cocrystal	NOUN
admet-497	114	99	with	with	ADP
admet-497	114	100	resorcinol	resorcinol	NOUN
admet-497	114	101	have	have	AUX
admet-497	114	102	been	be	AUX
admet-497	114	103	determined	determine	VERB
admet-497	114	104	at	at	ADP
admet-497	114	105	several	several	ADJ
admet-497	114	106	ph	ph	ADJ
admet-497	114	107	values	value	NOUN
admet-497	114	108	of	of	ADP
admet-497	114	109	pharmaceutical	pharmaceutical	ADJ
admet-497	114	110	interest	interest	NOUN
admet-497	114	111	in	in	ADP
admet-497	114	112	an	an	DET
admet-497	114	113	acetate	acetate	ADJ
admet-497	114	114	-	-	PUNCT
admet-497	114	115	phosphate	phosphate	NOUN
admet-497	114	116	buffer	buffer	NOUN
admet-497	114	117	.	.	PUNCT
admet-497	115	1	results	result	NOUN
admet-497	115	2	show	show	VERB
admet-497	115	3	that	that	SCONJ
admet-497	115	4	dissolution	dissolution	ADJ
admet-497	115	5	rate	rate	NOUN
admet-497	115	6	of	of	ADP
admet-497	115	7	ciprofloxacin	ciprofloxacin	NOUN
admet-497	115	8	decreases	decrease	NOUN
admet-497	115	9	according	accord	VERB
admet-497	115	10	to	to	ADP
admet-497	115	11	ionization	ionization	NOUN
admet-497	115	12	state	state	NOUN
admet-497	115	13	of	of	ADP
admet-497	115	14	ciprofloxacin	ciprofloxacin	PROPN
admet-497	115	15	,	,	PUNCT
admet-497	115	16	i.e.	i.e.	X
admet-497	115	17	,	,	PUNCT
admet-497	115	18	it	it	PRON
admet-497	115	19	is	be	AUX
admet-497	115	20	maximum	maximum	ADJ
admet-497	115	21	at	at	ADP
admet-497	115	22	ph	ph	PROPN
admet-497	115	23	2	2	NUM
admet-497	115	24	and	and	CCONJ
admet-497	115	25	has	have	VERB
admet-497	115	26	the	the	DET
admet-497	115	27	minimum	minimum	ADJ
admet-497	115	28	value	value	NOUN
admet-497	115	29	at	at	ADP
admet-497	115	30	ph	ph	PROPN
admet-497	115	31	7.4	7.4	NUM
admet-497	115	32	,	,	PUNCT
admet-497	115	33	where	where	SCONJ
admet-497	115	34	ciprofloxacin	ciprofloxacin	PROPN
admet-497	115	35	is	be	AUX
admet-497	115	36	mainly	mainly	ADV
admet-497	115	37	in	in	ADP
admet-497	115	38	its	its	PRON
admet-497	115	39	zwitterionic	zwitterionic	ADJ
admet-497	115	40	form	form	NOUN
admet-497	115	41	.	.	PUNCT
admet-497	116	1	the	the	DET
admet-497	116	2	same	same	ADJ
admet-497	116	3	behavior	behavior	NOUN
admet-497	116	4	is	be	AUX
admet-497	116	5	c.	c.	PROPN
admet-497	116	6	ràfols	ràfol	NOUN
admet-497	116	7	et	et	PROPN
admet-497	116	8	al	al	PROPN
admet-497	116	9	.	.	PROPN
admet-497	116	10	admet	admet	PROPN
admet-497	116	11	&	&	CCONJ
admet-497	116	12	dmpk	dmpk	PROPN
admet-497	116	13	6(1	6(1	NUM
admet-497	116	14	)	)	PUNCT
admet-497	116	15	(	(	PUNCT
admet-497	116	16	2018	2018	NUM
admet-497	116	17	)	)	PUNCT
admet-497	116	18	61	61	NUM
admet-497	116	19	-	-	SYM
admet-497	116	20	70	70	NUM
admet-497	116	21	68	68	NUM
admet-497	116	22	observed	observe	VERB
admet-497	116	23	with	with	ADP
admet-497	116	24	the	the	DET
admet-497	116	25	cocrystal	cocrystal	NOUN
admet-497	116	26	.	.	PUNCT
admet-497	117	1	however	however	ADV
admet-497	117	2	,	,	PUNCT
admet-497	117	3	ciprofloxacin	ciprofloxacin	PROPN
admet-497	117	4	dissolves	dissolve	VERB
admet-497	117	5	faster	fast	ADV
admet-497	117	6	than	than	ADP
admet-497	117	7	the	the	DET
admet-497	117	8	cocrystal	cocrystal	NOUN
admet-497	117	9	at	at	ADP
admet-497	117	10	ph	ph	PROPN
admet-497	117	11	2	2	NUM
admet-497	117	12	,	,	PUNCT
admet-497	117	13	but	but	CCONJ
admet-497	117	14	the	the	DET
admet-497	117	15	cocrystal	cocrystal	NOUN
admet-497	117	16	dissolves	dissolve	VERB
admet-497	117	17	faster	fast	ADV
admet-497	117	18	than	than	ADP
admet-497	117	19	ciprofloxacin	ciprofloxacin	NOUN
admet-497	117	20	at	at	ADP
admet-497	117	21	intermediate	intermediate	ADJ
admet-497	117	22	ph	ph	ADJ
admet-497	117	23	values	value	NOUN
admet-497	117	24	(	(	PUNCT
admet-497	117	25	4.0	4.0	NUM
admet-497	117	26	,	,	PUNCT
admet-497	117	27	5.0	5.0	NUM
admet-497	117	28	and	and	CCONJ
admet-497	117	29	5.5	5.5	NUM
admet-497	117	30	)	)	PUNCT
admet-497	117	31	.	.	PUNCT
admet-497	118	1	the	the	DET
admet-497	118	2	reason	reason	NOUN
admet-497	118	3	can	can	AUX
admet-497	118	4	be	be	AUX
admet-497	118	5	attributed	attribute	VERB
admet-497	118	6	either	either	ADV
admet-497	118	7	to	to	ADP
admet-497	118	8	a	a	DET
admet-497	118	9	better	well	ADJ
admet-497	118	10	dissolution	dissolution	NOUN
admet-497	118	11	of	of	ADP
admet-497	118	12	the	the	DET
admet-497	118	13	cocrystal	cocrystal	NOUN
admet-497	118	14	itself	itself	PRON
admet-497	118	15	,	,	PUNCT
admet-497	118	16	or	or	CCONJ
admet-497	118	17	a	a	DET
admet-497	118	18	decrease	decrease	NOUN
admet-497	118	19	in	in	ADP
admet-497	118	20	the	the	DET
admet-497	118	21	dissolution	dissolution	NOUN
admet-497	118	22	of	of	ADP
admet-497	118	23	ciprofloxacin	ciprofloxacin	NOUN
admet-497	118	24	due	due	ADP
admet-497	118	25	to	to	ADP
admet-497	118	26	the	the	DET
admet-497	118	27	formation	formation	NOUN
admet-497	118	28	of	of	ADP
admet-497	118	29	the	the	DET
admet-497	118	30	more	more	ADV
admet-497	118	31	insoluble	insoluble	ADJ
admet-497	118	32	trihydrated	trihydrate	VERB
admet-497	118	33	form	form	NOUN
admet-497	118	34	in	in	ADP
admet-497	118	35	the	the	DET
admet-497	118	36	surface	surface	NOUN
admet-497	118	37	of	of	ADP
admet-497	118	38	the	the	DET
admet-497	118	39	tablets	tablet	NOUN
admet-497	118	40	,	,	PUNCT
admet-497	118	41	as	as	SCONJ
admet-497	118	42	stated	state	VERB
admet-497	118	43	by	by	ADP
admet-497	118	44	pxrd	pxrd	PROPN
admet-497	118	45	.	.	PUNCT
admet-497	119	1	gastric	gastric	ADJ
admet-497	119	2	fluid	fluid	ADJ
admet-497	119	3	components	component	NOUN
admet-497	119	4	such	such	ADJ
admet-497	119	5	as	as	ADP
admet-497	119	6	lecithin	lecithin	NOUN
admet-497	119	7	and	and	CCONJ
admet-497	119	8	bile	bile	NOUN
admet-497	119	9	salts	salt	NOUN
admet-497	119	10	have	have	AUX
admet-497	119	11	not	not	PART
admet-497	119	12	shown	show	VERB
admet-497	119	13	any	any	DET
admet-497	119	14	improvement	improvement	NOUN
admet-497	119	15	in	in	ADP
admet-497	119	16	the	the	DET
admet-497	119	17	dissolution	dissolution	NOUN
admet-497	119	18	rate	rate	NOUN
admet-497	119	19	of	of	ADP
admet-497	119	20	the	the	DET
admet-497	119	21	studied	study	VERB
admet-497	119	22	compounds	compound	NOUN
admet-497	119	23	.	.	PUNCT
admet-497	120	1	figure	figure	NOUN
admet-497	120	2	5	5	NUM
admet-497	120	3	:	:	PUNCT
admet-497	120	4	dissolution	dissolution	NOUN
admet-497	120	5	profile	profile	NOUN
admet-497	120	6	in	in	ADP
admet-497	120	7	simulated	simulated	ADJ
admet-497	120	8	gastrointestinal	gastrointestinal	ADJ
admet-497	120	9	fluids	fluid	NOUN
admet-497	120	10	and	and	CCONJ
admet-497	120	11	buffer	buffer	VERB
admet-497	120	12	at	at	ADP
admet-497	120	13	the	the	DET
admet-497	120	14	same	same	ADJ
admet-497	120	15	ph	ph	NOUN
admet-497	120	16	.	.	PUNCT
admet-497	121	1	(	(	PUNCT
admet-497	121	2	a	a	X
admet-497	121	3	)	)	PUNCT
admet-497	121	4	cip	cip	NOUN
admet-497	121	5	in	in	ADP
admet-497	121	6	fessif	fessif	NOUN
admet-497	121	7	(	(	PUNCT
admet-497	121	8	●	●	NOUN
admet-497	121	9	)	)	PUNCT
admet-497	121	10	,	,	PUNCT
admet-497	121	11	cip	cip	NOUN
admet-497	121	12	in	in	ADP
admet-497	121	13	buffer	buffer	NOUN
admet-497	121	14	at	at	ADP
admet-497	121	15	ph	ph	NOUN
admet-497	121	16	5	5	NUM
admet-497	121	17	(	(	PUNCT
admet-497	121	18	▲	▲	NOUN
admet-497	121	19	)	)	PUNCT
admet-497	121	20	,	,	PUNCT
admet-497	121	21	cip	cip	NOUN
admet-497	121	22	-	-	PUNCT
admet-497	121	23	r	r	NOUN
admet-497	121	24	in	in	ADP
admet-497	121	25	fessif	fessif	NOUN
admet-497	121	26	(	(	PUNCT
admet-497	121	27	○	○	PROPN
admet-497	121	28	)	)	PUNCT
admet-497	121	29	,	,	PUNCT
admet-497	121	30	cip	cip	NOUN
admet-497	121	31	-	-	PUNCT
admet-497	121	32	r	r	NOUN
admet-497	121	33	in	in	ADP
admet-497	121	34	buffer	buffer	NOUN
admet-497	121	35	at	at	ADP
admet-497	121	36	ph	ph	PROPN
admet-497	121	37	5	5	NUM
admet-497	121	38	(	(	PUNCT
admet-497	121	39	∆	∆	PROPN
admet-497	121	40	)	)	PUNCT
admet-497	121	41	;	;	PUNCT
admet-497	121	42	(	(	PUNCT
admet-497	121	43	b	b	X
admet-497	121	44	)	)	PUNCT
admet-497	121	45	cip	cip	NOUN
admet-497	121	46	in	in	ADP
admet-497	121	47	fassif	fassif	NOUN
admet-497	121	48	(	(	PUNCT
admet-497	121	49	●	●	NOUN
admet-497	121	50	)	)	PUNCT
admet-497	121	51	,	,	PUNCT
admet-497	121	52	cip	cip	NOUN
admet-497	121	53	in	in	ADP
admet-497	121	54	buffer	buffer	NOUN
admet-497	121	55	at	at	ADP
admet-497	121	56	ph	ph	PROPN
admet-497	121	57	6.5	6.5	NUM
admet-497	121	58	(	(	PUNCT
admet-497	121	59	▲	▲	NOUN
admet-497	121	60	)	)	PUNCT
admet-497	121	61	,	,	PUNCT
admet-497	121	62	cip	cip	NOUN
admet-497	121	63	-	-	PUNCT
admet-497	121	64	r	r	NOUN
admet-497	121	65	in	in	ADP
admet-497	121	66	fassif	fassif	NOUN
admet-497	121	67	(	(	PUNCT
admet-497	121	68	○	○	PROPN
admet-497	121	69	)	)	PUNCT
admet-497	121	70	,	,	PUNCT
admet-497	121	71	cip	cip	NOUN
admet-497	121	72	-	-	PUNCT
admet-497	121	73	r	r	NOUN
admet-497	121	74	in	in	ADP
admet-497	121	75	buffer	buffer	NOUN
admet-497	121	76	at	at	ADP
admet-497	121	77	ph	ph	PROPN
admet-497	121	78	6.5	6.5	NUM
admet-497	121	79	(	(	PUNCT
admet-497	121	80	∆	∆	PROPN
admet-497	121	81	)	)	PUNCT
admet-497	121	82	.	.	PUNCT
admet-497	122	1	acknowledgements	acknowledgement	VERB
admet-497	122	2	the	the	DET
admet-497	122	3	authors	author	NOUN
admet-497	122	4	from	from	ADP
admet-497	122	5	the	the	DET
admet-497	122	6	university	university	PROPN
admet-497	122	7	of	of	ADP
admet-497	122	8	barcelona	barcelona	PROPN
admet-497	122	9	are	be	AUX
admet-497	122	10	grateful	grateful	ADJ
admet-497	122	11	for	for	ADP
admet-497	122	12	the	the	DET
admet-497	122	13	financial	financial	ADJ
admet-497	122	14	support	support	NOUN
admet-497	122	15	of	of	ADP
admet-497	122	16	the	the	DET
admet-497	122	17	spanish	spanish	ADJ
admet-497	122	18	government	government	NOUN
admet-497	122	19	(	(	PUNCT
admet-497	122	20	project	project	NOUN
admet-497	122	21	ctq2014	ctq2014	NOUN
admet-497	122	22	-	-	PUNCT
admet-497	122	23	56253	56253	NUM
admet-497	122	24	-	-	PUNCT
admet-497	122	25	p	p	NOUN
admet-497	122	26	)	)	PUNCT
admet-497	122	27	.	.	PUNCT
admet-497	123	1	references	reference	NOUN
admet-497	123	2	[	[	X
admet-497	123	3	1	1	X
admet-497	123	4	]	]	PUNCT
admet-497	123	5	e.	e.	PROPN
admet-497	123	6	merisko	merisko	PROPN
admet-497	123	7	,	,	PUNCT
admet-497	123	8	g.g	g.g	PROPN
admet-497	123	9	.	.	PROPN
admet-497	123	10	liversidge	liversidge	PROPN
admet-497	123	11	,	,	PUNCT
admet-497	123	12	nanocrystals	nanocrystal	NOUN
admet-497	123	13	:	:	PUNCT
admet-497	123	14	resolving	resolve	VERB
admet-497	123	15	pharmaceutical	pharmaceutical	ADJ
admet-497	123	16	formulation	formulation	NOUN
admet-497	123	17	issues	issue	NOUN
admet-497	123	18	associated	associate	VERB
admet-497	123	19	with	with	ADP
admet-497	123	20	poorly	poorly	ADV
admet-497	123	21	water	water	NOUN
admet-497	123	22	-	-	PUNCT
admet-497	123	23	soluble	soluble	ADJ
admet-497	123	24	compounds	compound	NOUN
admet-497	123	25	.	.	PUNCT
admet-497	124	1	in	in	ADP
admet-497	124	2	:	:	PUNCT
admet-497	124	3	particles	particle	NOUN
admet-497	124	4	;	;	PUNCT
admet-497	124	5	j.j	j.j	PROPN
admet-497	124	6	.	.	PROPN
admet-497	124	7	marty	marty	PROPN
admet-497	124	8	(	(	PUNCT
admet-497	124	9	ed	ed	NOUN
admet-497	124	10	.	.	PUNCT
admet-497	124	11	)	)	PUNCT
admet-497	124	12	.	.	PUNCT
admet-497	125	1	marcel	marcel	PROPN
admet-497	125	2	dekker	dekker	PROPN
admet-497	125	3	,	,	PUNCT
admet-497	125	4	orlando	orlando	PROPN
admet-497	125	5	,	,	PUNCT
admet-497	125	6	fl	fl	PROPN
admet-497	125	7	,	,	PUNCT
admet-497	125	8	usa	usa	PROPN
admet-497	125	9	,	,	PUNCT
admet-497	125	10	2002	2002	NUM
admet-497	125	11	.	.	PUNCT
admet-497	126	1	[	[	X
admet-497	126	2	2	2	X
admet-497	126	3	]	]	PUNCT
admet-497	126	4	s.	s.	PROPN
admet-497	126	5	sareen	sareen	PROPN
admet-497	126	6	,	,	PUNCT
admet-497	126	7	g.	g.	PROPN
admet-497	126	8	mathew	mathew	PROPN
admet-497	126	9	,	,	PUNCT
admet-497	126	10	l.	l.	PROPN
admet-497	126	11	joseph	joseph	PROPN
admet-497	126	12	.	.	PUNCT
admet-497	127	1	improvement	improvement	NOUN
admet-497	127	2	in	in	ADP
admet-497	127	3	solubility	solubility	NOUN
admet-497	127	4	of	of	ADP
admet-497	127	5	poor	poor	ADJ
admet-497	127	6	water	water	NOUN
admet-497	127	7	soluble	soluble	ADJ
admet-497	127	8	drugs	drug	NOUN
admet-497	127	9	by	by	ADP
admet-497	127	10	solid	solid	ADJ
admet-497	127	11	dispersion	dispersion	NOUN
admet-497	127	12	.	.	PUNCT
admet-497	128	1	international	international	ADJ
admet-497	128	2	journal	journal	PROPN
admet-497	128	3	of	of	ADP
admet-497	128	4	pharmaceutical	pharmaceutical	ADJ
admet-497	128	5	investigation	investigation	NOUN
admet-497	128	6	2	2	NUM
admet-497	128	7	(	(	PUNCT
admet-497	128	8	2012	2012	NUM
admet-497	128	9	)	)	PUNCT
admet-497	128	10	12–17	12–17	NUM
admet-497	128	11	.	.	PUNCT
admet-497	129	1	admet	admet	PROPN
admet-497	129	2	&	&	CCONJ
admet-497	129	3	dmpk	dmpk	PROPN
admet-497	129	4	6(1	6(1	NUM
admet-497	129	5	)	)	PUNCT
admet-497	129	6	(	(	PUNCT
admet-497	129	7	2018	2018	NUM
admet-497	129	8	)	)	PUNCT
admet-497	129	9	61	61	NUM
admet-497	129	10	-	-	SYM
admet-497	129	11	70	70	NUM
admet-497	129	12	dissolution	dissolution	NOUN
admet-497	129	13	rates	rate	NOUN
admet-497	129	14	of	of	ADP
admet-497	129	15	ciprofloxacin	ciprofloxacin	PROPN
admet-497	129	16	and	and	CCONJ
admet-497	129	17	its	its	PRON
admet-497	129	18	cocrystal	cocrystal	NOUN
admet-497	129	19	with	with	ADP
admet-497	129	20	resorcinol	resorcinol	NOUN
admet-497	129	21	doi	doi	NOUN
admet-497	129	22	:	:	PUNCT
admet-497	129	23	10.5599	10.5599	NUM
admet-497	129	24	/	/	SYM
admet-497	129	25	admet.6.1.497	admet.6.1.497	PROPN
admet-497	129	26	69	69	NUM
admet-497	130	1	[	[	X
admet-497	130	2	3	3	NUM
admet-497	130	3	]	]	X
admet-497	130	4	s.v	s.v	PROPN
admet-497	130	5	.	.	PROPN
admet-497	130	6	kurkov	kurkov	PROPN
admet-497	130	7	,	,	PUNCT
admet-497	130	8	t.	t.	PROPN
admet-497	130	9	loftsson	loftsson	NOUN
admet-497	130	10	.	.	PUNCT
admet-497	131	1	cyclodextrins	cyclodextrin	NOUN
admet-497	131	2	.	.	PUNCT
admet-497	132	1	international	international	ADJ
admet-497	132	2	journal	journal	PROPN
admet-497	132	3	of	of	ADP
admet-497	132	4	pharmacy	pharmacy	NOUN
admet-497	132	5	453	453	NUM
admet-497	132	6	(	(	PUNCT
admet-497	132	7	2013	2013	NUM
admet-497	132	8	)	)	PUNCT
admet-497	132	9	167–180	167–180	NUM
admet-497	132	10	.	.	PUNCT
admet-497	133	1	[	[	X
admet-497	133	2	4	4	NUM
admet-497	133	3	]	]	X
admet-497	133	4	n.j	n.j	PROPN
admet-497	133	5	.	.	PROPN
admet-497	133	6	babu	babu	PROPN
admet-497	133	7	,	,	PUNCT
admet-497	133	8	a.	a.	PROPN
admet-497	133	9	nanjia	nanjia	PROPN
admet-497	133	10	.	.	PUNCT
admet-497	134	1	solubility	solubility	NOUN
admet-497	134	2	advantage	advantage	NOUN
admet-497	134	3	of	of	ADP
admet-497	134	4	amorphous	amorphous	ADJ
admet-497	134	5	drugs	drug	NOUN
admet-497	134	6	and	and	CCONJ
admet-497	134	7	pharmaceutical	pharmaceutical	NOUN
admet-497	134	8	co	co	NOUN
admet-497	134	9	-	-	NOUN
admet-497	134	10	crystals	crystal	NOUN
admet-497	134	11	.	.	PUNCT
admet-497	135	1	crystal	crystal	NOUN
admet-497	135	2	growth	growth	NOUN
admet-497	135	3	and	and	CCONJ
admet-497	135	4	design	design	NOUN
admet-497	135	5	11	11	NUM
admet-497	135	6	(	(	PUNCT
admet-497	135	7	2011	2011	NUM
admet-497	135	8	)	)	PUNCT
admet-497	135	9	2662–2679	2662–2679	NUM
admet-497	135	10	.	.	PUNCT
admet-497	136	1	[	[	X
admet-497	136	2	5	5	NUM
admet-497	136	3	]	]	X
admet-497	136	4	n.	n.	NOUN
admet-497	136	5	schultheiss	schultheiss	PROPN
admet-497	136	6	,	,	PUNCT
admet-497	136	7	a.	a.	PROPN
admet-497	136	8	newman	newman	PROPN
admet-497	136	9	.	.	PUNCT
admet-497	137	1	pharmaceutical	pharmaceutical	PROPN
admet-497	137	2	cocrystals	cocrystal	NOUN
admet-497	137	3	and	and	CCONJ
admet-497	137	4	their	their	PRON
admet-497	137	5	physicochemical	physicochemical	ADJ
admet-497	137	6	properties	property	NOUN
admet-497	137	7	.	.	PUNCT
admet-497	138	1	crystal	crystal	NOUN
admet-497	138	2	growth	growth	NOUN
admet-497	138	3	and	and	CCONJ
admet-497	138	4	design	design	NOUN
admet-497	138	5	9	9	NUM
admet-497	138	6	(	(	PUNCT
admet-497	138	7	2009	2009	NUM
admet-497	138	8	)	)	PUNCT
admet-497	138	9	2950–2967	2950–2967	NUM
admet-497	138	10	.	.	PUNCT
admet-497	139	1	[	[	X
admet-497	139	2	6	6	NUM
admet-497	139	3	]	]	X
admet-497	139	4	n.	n.	PROPN
admet-497	139	5	qiao	qiao	PROPN
admet-497	139	6	,	,	PUNCT
admet-497	139	7	m.	m.	PROPN
admet-497	139	8	li	li	PROPN
admet-497	139	9	,	,	PUNCT
admet-497	139	10	w.	w.	PROPN
admet-497	139	11	schlindwein	schlindwein	PROPN
admet-497	139	12	,	,	PUNCT
admet-497	139	13	n.	n.	PROPN
admet-497	139	14	malek	malek	PROPN
admet-497	139	15	,	,	PUNCT
admet-497	139	16	a.	a.	NOUN
admet-497	139	17	davies	davy	NOUN
admet-497	139	18	,	,	PUNCT
admet-497	139	19	g.	g.	PROPN
admet-497	139	20	trapitt	trapitt	NOUN
admet-497	139	21	.	.	PUNCT
admet-497	140	1	pharmaceutical	pharmaceutical	PROPN
admet-497	140	2	co	co	NOUN
admet-497	140	3	-	-	NOUN
admet-497	141	1	crystals	crystal	NOUN
admet-497	141	2	:	:	PUNCT
admet-497	141	3	an	an	DET
admet-497	141	4	overview	overview	NOUN
admet-497	141	5	.	.	PUNCT
admet-497	142	1	international	international	ADJ
admet-497	142	2	journal	journal	NOUN
admet-497	142	3	of	of	ADP
admet-497	142	4	pharmacy	pharmacy	NOUN
admet-497	142	5	419	419	NUM
admet-497	142	6	(	(	PUNCT
admet-497	142	7	2011	2011	NUM
admet-497	142	8	)	)	PUNCT
admet-497	142	9	1–11	1–11	PROPN
admet-497	142	10	.	.	PUNCT
admet-497	143	1	[	[	X
admet-497	143	2	7	7	NUM
admet-497	143	3	]	]	SYM
admet-497	143	4	r.d.b	r.d.b	PROPN
admet-497	143	5	.	.	PUNCT
admet-497	143	6	walsh	walsh	PROPN
admet-497	143	7	,	,	PUNCT
admet-497	143	8	m.w	m.w	PROPN
admet-497	143	9	.	.	PROPN
admet-497	143	10	bradner	bradner	PROPN
admet-497	143	11	,	,	PUNCT
admet-497	143	12	s.g	s.g	PROPN
admet-497	143	13	.	.	PROPN
admet-497	143	14	fleischman	fleischman	PROPN
admet-497	143	15	,	,	PUNCT
admet-497	143	16	l.a	l.a	PROPN
admet-497	143	17	.	.	PROPN
admet-497	143	18	morales	morales	PROPN
admet-497	143	19	,	,	PUNCT
admet-497	143	20	b.	b.	PROPN
admet-497	143	21	moulton	moulton	PROPN
admet-497	143	22	,	,	PUNCT
admet-497	143	23	n.	n.	PROPN
admet-497	143	24	rodriguez	rodriguez	PROPN
admet-497	143	25	-	-	PUNCT
admet-497	143	26	hornedo	hornedo	PROPN
admet-497	143	27	,	,	PUNCT
admet-497	143	28	m.j	m.j	PROPN
admet-497	143	29	.	.	PROPN
admet-497	143	30	zaworotko	zaworotko	PROPN
admet-497	143	31	.	.	PUNCT
admet-497	144	1	crystal	crystal	PROPN
admet-497	144	2	engineering	engineering	NOUN
admet-497	144	3	of	of	ADP
admet-497	144	4	the	the	DET
admet-497	144	5	composition	composition	NOUN
admet-497	144	6	of	of	ADP
admet-497	144	7	pharmaceutical	pharmaceutical	ADJ
admet-497	144	8	phases	phase	NOUN
admet-497	144	9	.	.	PUNCT
admet-497	145	1	chemical	chemical	NOUN
admet-497	145	2	communications	communication	NOUN
admet-497	145	3	(	(	PUNCT
admet-497	145	4	2003	2003	NUM
admet-497	145	5	)	)	PUNCT
admet-497	145	6	186	186	NUM
admet-497	145	7	-	-	SYM
admet-497	145	8	187	187	NUM
admet-497	145	9	.	.	PUNCT
admet-497	146	1	[	[	X
admet-497	146	2	8	8	NUM
admet-497	146	3	]	]	PUNCT
admet-497	146	4	k.	k.	PROPN
admet-497	146	5	fucke	fucke	PROPN
admet-497	146	6	,	,	PUNCT
admet-497	146	7	s.	s.	PROPN
admet-497	146	8	a.	a.	PROPN
admet-497	146	9	myz	myz	PROPN
admet-497	146	10	,	,	PUNCT
admet-497	146	11	t.p	t.p	PROPN
admet-497	146	12	.	.	PROPN
admet-497	146	13	shakhtshneider	shakhtshneider	PROPN
admet-497	146	14	,	,	PUNCT
admet-497	146	15	e.v	e.v	PROPN
admet-497	146	16	.	.	PROPN
admet-497	146	17	boldyreva	boldyreva	PROPN
admet-497	146	18	,	,	PUNCT
admet-497	146	19	u.j	u.j	PROPN
admet-497	146	20	.	.	PROPN
admet-497	146	21	griesser	griesser	NOUN
admet-497	146	22	.	.	PUNCT
admet-497	147	1	how	how	SCONJ
admet-497	147	2	good	good	ADJ
admet-497	147	3	are	be	AUX
admet-497	147	4	the	the	DET
admet-497	147	5	crystallisation	crystallisation	NOUN
admet-497	147	6	methods	method	NOUN
admet-497	147	7	for	for	ADP
admet-497	147	8	co	co	NOUN
admet-497	147	9	-	-	NOUN
admet-497	147	10	crystals	crystal	NOUN
admet-497	147	11	?	?	PUNCT
admet-497	148	1	a	a	DET
admet-497	148	2	comparative	comparative	ADJ
admet-497	148	3	study	study	NOUN
admet-497	148	4	of	of	ADP
admet-497	148	5	piroxicam	piroxicam	NOUN
admet-497	148	6	.	.	PUNCT
admet-497	149	1	new	new	ADJ
admet-497	149	2	journal	journal	NOUN
admet-497	149	3	of	of	ADP
admet-497	149	4	chemistry	chemistry	NOUN
admet-497	149	5	36	36	NUM
admet-497	149	6	(	(	PUNCT
admet-497	149	7	2012	2012	NUM
admet-497	149	8	)	)	PUNCT
admet-497	149	9	1969	1969	NUM
admet-497	149	10	-	-	SYM
admet-497	149	11	1977	1977	NUM
admet-497	149	12	.	.	PUNCT
admet-497	150	1	[	[	X
admet-497	150	2	9	9	NUM
admet-497	150	3	]	]	X
admet-497	150	4	d.r	d.r	PROPN
admet-497	150	5	.	.	PROPN
admet-497	150	6	weyna	weyna	PROPN
admet-497	150	7	,	,	PUNCT
admet-497	150	8	t.	t.	NOUN
admet-497	150	9	shattock	shattock	NOUN
admet-497	150	10	,	,	PUNCT
admet-497	150	11	p.	p.	NOUN
admet-497	150	12	vishweshwar	vishweshwar	NOUN
admet-497	150	13	,	,	PUNCT
admet-497	150	14	m.j	m.j	PROPN
admet-497	150	15	.	.	PROPN
admet-497	150	16	zaworotko	zaworotko	PROPN
admet-497	150	17	.	.	PUNCT
admet-497	151	1	synthesis	synthesis	NOUN
admet-497	151	2	and	and	CCONJ
admet-497	151	3	structural	structural	ADJ
admet-497	151	4	characterization	characterization	NOUN
admet-497	151	5	of	of	ADP
admet-497	151	6	cocrystals	cocrystal	NOUN
admet-497	151	7	and	and	CCONJ
admet-497	151	8	pharmaceutical	pharmaceutical	NOUN
admet-497	151	9	cocrystals	cocrystal	NOUN
admet-497	151	10	:	:	PUNCT
admet-497	151	11	mechanochemistry	mechanochemistry	NOUN
admet-497	151	12	vs	vs	ADP
admet-497	151	13	slow	slow	ADJ
admet-497	151	14	evaporation	evaporation	NOUN
admet-497	151	15	from	from	ADP
admet-497	151	16	solution	solution	NOUN
admet-497	151	17	.	.	PUNCT
admet-497	152	1	crystal	crystal	NOUN
admet-497	152	2	growth	growth	NOUN
admet-497	152	3	and	and	CCONJ
admet-497	152	4	design	design	NOUN
admet-497	152	5	9	9	NUM
admet-497	152	6	(	(	PUNCT
admet-497	152	7	2009	2009	NUM
admet-497	152	8	)	)	PUNCT
admet-497	152	9	1106–1123	1106–1123	NUM
admet-497	152	10	.	.	PUNCT
admet-497	153	1	[	[	X
admet-497	153	2	10	10	NUM
admet-497	153	3	]	]	X
admet-497	153	4	n.	n.	NOUN
admet-497	153	5	takata	takata	PROPN
admet-497	153	6	,	,	PUNCT
admet-497	153	7	k.	k.	PROPN
admet-497	153	8	shiraki	shiraki	PROPN
admet-497	153	9	,	,	PUNCT
admet-497	153	10	r.	r.	PROPN
admet-497	153	11	takano	takano	PROPN
admet-497	153	12	,	,	PUNCT
admet-497	153	13	y.	y.	PROPN
admet-497	153	14	hayashi	hayashi	PROPN
admet-497	153	15	,	,	PUNCT
admet-497	153	16	y.	y.	PROPN
admet-497	153	17	terada	terada	PROPN
admet-497	153	18	.	.	PUNCT
admet-497	154	1	co	co	PROPN
admet-497	154	2	-	-	NOUN
admet-497	154	3	crystal	crystal	ADJ
admet-497	154	4	screening	screen	VERB
admet-497	154	5	stanolone	stanolone	NOUN
admet-497	154	6	and	and	CCONJ
admet-497	154	7	mestanolone	mestanolone	NOUN
admet-497	154	8	using	use	VERB
admet-497	154	9	slurry	slurry	NOUN
admet-497	154	10	crystallization	crystallization	NOUN
admet-497	154	11	.	.	PUNCT
admet-497	155	1	crystal	crystal	NOUN
admet-497	155	2	growth	growth	NOUN
admet-497	155	3	and	and	CCONJ
admet-497	155	4	design	design	NOUN
admet-497	155	5	8	8	NUM
admet-497	155	6	(	(	PUNCT
admet-497	155	7	2008	2008	NUM
admet-497	155	8	)	)	PUNCT
admet-497	155	9	3032	3032	NUM
admet-497	155	10	-	-	SYM
admet-497	155	11	3037	3037	NUM
admet-497	155	12	.	.	PUNCT
admet-497	156	1	[	[	X
admet-497	156	2	11	11	NUM
admet-497	156	3	]	]	PUNCT
admet-497	156	4	t.	t.	NOUN
admet-497	156	5	friščić	friščić	NOUN
admet-497	156	6	,	,	PUNCT
admet-497	156	7	w.	w.	PROPN
admet-497	156	8	jones	jones	PROPN
admet-497	156	9	.	.	PUNCT
admet-497	157	1	recent	recent	ADJ
admet-497	157	2	advances	advance	NOUN
admet-497	157	3	in	in	ADP
admet-497	157	4	understanding	understand	VERB
admet-497	157	5	the	the	DET
admet-497	157	6	mechanism	mechanism	NOUN
admet-497	157	7	of	of	ADP
admet-497	157	8	cocrystal	cocrystal	ADJ
admet-497	157	9	formation	formation	NOUN
admet-497	157	10	via	via	ADP
admet-497	157	11	grinding	grind	VERB
admet-497	157	12	.	.	PUNCT
admet-497	158	1	crystal	crystal	NOUN
admet-497	158	2	growth	growth	NOUN
admet-497	158	3	and	and	CCONJ
admet-497	158	4	design	design	NOUN
admet-497	158	5	9	9	NUM
admet-497	158	6	(	(	PUNCT
admet-497	158	7	2009	2009	NUM
admet-497	158	8	)	)	PUNCT
admet-497	158	9	1621	1621	NUM
admet-497	158	10	-	-	SYM
admet-497	158	11	1637	1637	NUM
admet-497	158	12	.	.	PUNCT
admet-497	159	1	[	[	X
admet-497	159	2	12	12	NUM
admet-497	159	3	]	]	PUNCT
admet-497	159	4	a.	a.	NOUN
admet-497	159	5	v.	v.	PROPN
admet-497	159	6	trask	trask	PROPN
admet-497	159	7	,	,	PUNCT
admet-497	159	8	w.	w.	PROPN
admet-497	159	9	jones	jones	PROPN
admet-497	159	10	.	.	PUNCT
admet-497	160	1	crystal	crystal	PROPN
admet-497	160	2	engineering	engineering	NOUN
admet-497	160	3	of	of	ADP
admet-497	160	4	organic	organic	ADJ
admet-497	160	5	co	co	NOUN
admet-497	160	6	-	-	NOUN
admet-497	160	7	crystals	crystal	NOUN
admet-497	160	8	by	by	ADP
admet-497	160	9	the	the	DET
admet-497	160	10	solid	solid	ADJ
admet-497	160	11	-	-	PUNCT
admet-497	160	12	state	state	NOUN
admet-497	160	13	grinding	grind	VERB
admet-497	160	14	approach	approach	NOUN
admet-497	160	15	.	.	PUNCT
admet-497	161	1	topics	topic	NOUN
admet-497	161	2	in	in	ADP
admet-497	161	3	current	current	ADJ
admet-497	161	4	chemistry	chemistry	NOUN
admet-497	161	5	254	254	NUM
admet-497	161	6	(	(	PUNCT
admet-497	161	7	2005	2005	NUM
admet-497	161	8	)	)	PUNCT
admet-497	161	9	41	41	NUM
admet-497	161	10	-	-	SYM
admet-497	161	11	70	70	NUM
admet-497	161	12	.	.	PUNCT
admet-497	162	1	[	[	X
admet-497	162	2	13	13	NUM
admet-497	162	3	]	]	X
admet-497	162	4	n.	n.	PROPN
admet-497	162	5	blagden	blagden	PROPN
admet-497	162	6	,	,	PUNCT
admet-497	162	7	d.j	d.j	PROPN
admet-497	162	8	.	.	PROPN
admet-497	162	9	berry	berry	PROPN
admet-497	162	10	,	,	PUNCT
admet-497	162	11	a.	a.	NOUN
admet-497	162	12	parkin	parkin	PROPN
admet-497	162	13	,	,	PUNCT
admet-497	162	14	h.	h.	PROPN
admet-497	162	15	javed	javed	PROPN
admet-497	162	16	,	,	PUNCT
admet-497	162	17	a.	a.	PROPN
admet-497	162	18	ibrahim	ibrahim	PROPN
admet-497	162	19	,	,	PUNCT
admet-497	162	20	p.t	p.t	PROPN
admet-497	162	21	.	.	PROPN
admet-497	162	22	gavan	gavan	PROPN
admet-497	162	23	,	,	PUNCT
admet-497	162	24	l.l	l.l	PROPN
admet-497	162	25	.	.	PROPN
admet-497	162	26	de	de	X
admet-497	162	27	matos	matos	PROPN
admet-497	162	28	,	,	PUNCT
admet-497	162	29	c.c	c.c	PROPN
admet-497	162	30	.	.	PROPN
admet-497	162	31	seaton	seaton	PROPN
admet-497	162	32	.	.	PUNCT
admet-497	163	1	current	current	ADJ
admet-497	163	2	directions	direction	NOUN
admet-497	163	3	in	in	ADP
admet-497	163	4	co	co	ADJ
admet-497	163	5	-	-	NOUN
admet-497	163	6	crystal	crystal	ADJ
admet-497	163	7	growth	growth	NOUN
admet-497	163	8	.	.	PUNCT
admet-497	164	1	new	new	ADJ
admet-497	164	2	journal	journal	NOUN
admet-497	164	3	of	of	ADP
admet-497	164	4	chemistry	chemistry	NOUN
admet-497	164	5	32	32	NUM
admet-497	164	6	(	(	PUNCT
admet-497	164	7	2008	2008	NUM
admet-497	164	8	)	)	PUNCT
admet-497	164	9	1659	1659	NUM
admet-497	164	10	-	-	SYM
admet-497	164	11	1672	1672	NUM
admet-497	164	12	.	.	PUNCT
admet-497	165	1	[	[	X
admet-497	165	2	14	14	NUM
admet-497	165	3	]	]	X
admet-497	165	4	e.	e.	PROPN
admet-497	165	5	shoghi	shoghi	PROPN
admet-497	165	6	,	,	PUNCT
admet-497	165	7	e.	e.	PROPN
admet-497	165	8	fuguet	fuguet	PROPN
admet-497	165	9	,	,	PUNCT
admet-497	165	10	e.	e.	PROPN
admet-497	165	11	bosch	bosch	PROPN
admet-497	165	12	,	,	PUNCT
admet-497	165	13	c.	c.	PROPN
admet-497	165	14	ràfols	ràfol	NOUN
admet-497	165	15	.	.	PUNCT
admet-497	166	1	solubility	solubility	NOUN
admet-497	166	2	-	-	PUNCT
admet-497	166	3	ph	ph	ADJ
admet-497	166	4	profiles	profile	NOUN
admet-497	166	5	of	of	ADP
admet-497	166	6	some	some	DET
admet-497	166	7	acidic	acidic	ADJ
admet-497	166	8	,	,	PUNCT
admet-497	166	9	basic	basic	ADJ
admet-497	166	10	and	and	CCONJ
admet-497	166	11	amphoteric	amphoteric	ADJ
admet-497	166	12	drugs	drug	NOUN
admet-497	166	13	.	.	PUNCT
admet-497	167	1	european	european	ADJ
admet-497	167	2	journal	journal	PROPN
admet-497	167	3	of	of	ADP
admet-497	167	4	pharmaceutical	pharmaceutical	PROPN
admet-497	167	5	sciences	science	NOUN
admet-497	167	6	48	48	NUM
admet-497	167	7	(	(	PUNCT
admet-497	167	8	2013	2013	NUM
admet-497	167	9	)	)	PUNCT
admet-497	167	10	291	291	NUM
admet-497	167	11	-	-	SYM
admet-497	167	12	300	300	NUM
admet-497	167	13	.	.	PUNCT
admet-497	168	1	[	[	X
admet-497	168	2	15	15	NUM
admet-497	168	3	]	]	X
admet-497	168	4	t.	t.	NOUN
admet-497	168	5	gravestock	gravestock	NOUN
admet-497	168	6	,	,	PUNCT
admet-497	168	7	k.	k.	PROPN
admet-497	168	8	box	box	PROPN
admet-497	168	9	,	,	PUNCT
admet-497	168	10	j.	j.	PROPN
admet-497	168	11	comer	comer	PROPN
admet-497	168	12	,	,	PUNCT
admet-497	168	13	e.	e.	PROPN
admet-497	168	14	frake	frake	PROPN
admet-497	168	15	,	,	PUNCT
admet-497	168	16	s.	s.	PROPN
admet-497	168	17	judge	judge	PROPN
admet-497	168	18	,	,	PUNCT
admet-497	168	19	r.	r.	PROPN
admet-497	168	20	ruiz	ruiz	PROPN
admet-497	168	21	.	.	PUNCT
admet-497	169	1	the	the	DET
admet-497	169	2	“	"	PUNCT
admet-497	169	3	gi	gi	NOUN
admet-497	169	4	dissolution	dissolution	NOUN
admet-497	169	5	”	"	PUNCT
admet-497	169	6	method	method	NOUN
admet-497	169	7	:	:	PUNCT
admet-497	169	8	a	a	DET
admet-497	169	9	low	low	ADJ
admet-497	169	10	volume	volume	NOUN
admet-497	169	11	,	,	PUNCT
admet-497	169	12	in	in	ADP
admet-497	169	13	vitro	vitro	X
admet-497	169	14	apparatus	apparatus	NOUN
admet-497	169	15	for	for	ADP
admet-497	169	16	assessing	assess	VERB
admet-497	169	17	the	the	DET
admet-497	169	18	dissolution	dissolution	NOUN
admet-497	169	19	/	/	SYM
admet-497	169	20	precipitation	precipitation	NOUN
admet-497	169	21	behaviour	behaviour	NOUN
admet-497	169	22	of	of	ADP
admet-497	169	23	an	an	DET
admet-497	169	24	active	active	ADJ
admet-497	169	25	pharmaceutical	pharmaceutical	ADJ
admet-497	169	26	ingredient	ingredient	NOUN
admet-497	169	27	under	under	ADP
admet-497	169	28	biorelevant	biorelevant	ADJ
admet-497	169	29	conditions	condition	NOUN
admet-497	169	30	.	.	PUNCT
admet-497	170	1	analytical	analytical	ADJ
admet-497	170	2	methods	method	NOUN
admet-497	170	3	3	3	NUM
admet-497	170	4	(	(	PUNCT
admet-497	170	5	2011	2011	NUM
admet-497	170	6	)	)	PUNCT
admet-497	170	7	560	560	NUM
admet-497	170	8	-	-	SYM
admet-497	170	9	567	567	NUM
admet-497	170	10	.	.	PUNCT
admet-497	171	1	[	[	X
admet-497	171	2	16	16	NUM
admet-497	171	3	]	]	X
admet-497	171	4	c.	c.	NOUN
admet-497	171	5	ràfols	ràfols	PROPN
admet-497	171	6	,	,	PUNCT
admet-497	171	7	x.	x.	NOUN
admet-497	171	8	subirats	subirat	NOUN
admet-497	171	9	,	,	PUNCT
admet-497	171	10	j.	j.	PROPN
admet-497	171	11	rubio	rubio	PROPN
admet-497	171	12	,	,	PUNCT
admet-497	171	13	m.	m.	NOUN
admet-497	171	14	rosés	rosés	PROPN
admet-497	171	15	,	,	PUNCT
admet-497	171	16	e.	e.	PROPN
admet-497	171	17	bosch	bosch	PROPN
admet-497	171	18	.	.	PUNCT
admet-497	172	1	lipophilicity	lipophilicity	NOUN
admet-497	172	2	of	of	ADP
admet-497	172	3	amphoteric	amphoteric	ADJ
admet-497	172	4	and	and	CCONJ
admet-497	172	5	zwitterionic	zwitterionic	ADJ
admet-497	172	6	compounds	compound	NOUN
admet-497	172	7	:	:	PUNCT
admet-497	172	8	a	a	DET
admet-497	172	9	comparative	comparative	ADJ
admet-497	172	10	study	study	NOUN
admet-497	172	11	of	of	ADP
admet-497	172	12	determination	determination	NOUN
admet-497	172	13	methods	method	NOUN
admet-497	172	14	.	.	PUNCT
admet-497	173	1	talanta	talanta	PROPN
admet-497	173	2	162	162	NUM
admet-497	173	3	(	(	PUNCT
admet-497	173	4	2017	2017	NUM
admet-497	173	5	)	)	PUNCT
admet-497	173	6	293	293	NUM
admet-497	173	7	-	-	SYM
admet-497	173	8	299	299	NUM
admet-497	173	9	.	.	PUNCT
admet-497	174	1	[	[	X
admet-497	174	2	17	17	NUM
admet-497	174	3	]	]	X
admet-497	174	4	g.	g.	PROPN
admet-497	174	5	völgyi	völgyi	PROPN
admet-497	174	6	,	,	PUNCT
admet-497	174	7	g.	g.	PROPN
admet-497	174	8	vizserálek	vizserálek	PROPN
admet-497	174	9	,	,	PUNCT
admet-497	174	10	k.	k.	PROPN
admet-497	174	11	tackáks	tackáks	PROPN
admet-497	174	12	-	-	PUNCT
admet-497	174	13	novák	novák	PROPN
admet-497	174	14	,	,	PUNCT
admet-497	174	15	a.	a.	PROPN
admet-497	174	16	avdeef	avdeef	PROPN
admet-497	174	17	,	,	PUNCT
admet-497	174	18	k.y	k.y	PROPN
admet-497	174	19	.	.	PROPN
admet-497	174	20	tam	tam	PROPN
admet-497	174	21	.	.	PUNCT
admet-497	174	22	predicting	predict	VERB
admet-497	174	23	the	the	DET
admet-497	174	24	exposure	exposure	NOUN
admet-497	174	25	and	and	CCONJ
admet-497	174	26	antibacterial	antibacterial	ADJ
admet-497	174	27	activity	activity	NOUN
admet-497	174	28	of	of	ADP
admet-497	174	29	fluoroquinolones	fluoroquinolone	NOUN
admet-497	174	30	based	base	VERB
admet-497	174	31	on	on	ADP
admet-497	174	32	physicochemical	physicochemical	ADJ
admet-497	174	33	properties	property	NOUN
admet-497	174	34	.	.	PUNCT
admet-497	175	1	european	european	ADJ
admet-497	175	2	journal	journal	PROPN
admet-497	175	3	of	of	ADP
admet-497	175	4	pharmceutical	pharmceutical	ADJ
admet-497	175	5	sciencies	sciencie	NOUN
admet-497	175	6	47	47	NUM
admet-497	175	7	(	(	PUNCT
admet-497	175	8	2012	2012	NUM
admet-497	175	9	)	)	PUNCT
admet-497	175	10	21	21	NUM
admet-497	175	11	-	-	SYM
admet-497	175	12	17	17	NUM
admet-497	175	13	.	.	PUNCT
admet-497	176	1	[	[	X
admet-497	176	2	18	18	NUM
admet-497	176	3	]	]	X
admet-497	176	4	d.l	d.l	PROPN
admet-497	176	5	.	.	PROPN
admet-497	176	6	ross	ross	PROPN
admet-497	176	7	,	,	PUNCT
admet-497	176	8	c.m	c.m	PROPN
admet-497	176	9	.	.	PROPN
admet-497	176	10	riley	riley	PROPN
admet-497	176	11	.	.	PUNCT
admet-497	177	1	aqueous	aqueous	ADJ
admet-497	177	2	solubilities	solubility	NOUN
admet-497	177	3	of	of	ADP
admet-497	177	4	some	some	DET
admet-497	177	5	variously	variously	ADV
admet-497	177	6	substituted	substitute	VERB
admet-497	177	7	quinolone	quinolone	NOUN
admet-497	177	8	antibacterials	antibacterial	NOUN
admet-497	177	9	.	.	PUNCT
admet-497	178	1	international	international	ADJ
admet-497	178	2	journal	journal	PROPN
admet-497	178	3	of	of	ADP
admet-497	178	4	pharmaceutics	pharmaceutic	NOUN
admet-497	178	5	63	63	NUM
admet-497	178	6	(	(	PUNCT
admet-497	178	7	1990	1990	NUM
admet-497	178	8	)	)	PUNCT
admet-497	178	9	237–250	237–250	NUM
admet-497	178	10	.	.	PUNCT
admet-497	179	1	[	[	X
admet-497	179	2	19	19	NUM
admet-497	179	3	]	]	PUNCT
admet-497	179	4	a.	a.	NOUN
admet-497	179	5	avdeef	avdeef	PROPN
admet-497	179	6	.	.	PUNCT
admet-497	180	1	physocochemical	physocochemical	ADJ
admet-497	180	2	profiling	profiling	NOUN
admet-497	180	3	(	(	PUNCT
admet-497	180	4	solubility	solubility	NOUN
admet-497	180	5	,	,	PUNCT
admet-497	180	6	permeability	permeability	NOUN
admet-497	180	7	and	and	CCONJ
admet-497	180	8	charge	charge	NOUN
admet-497	180	9	state	state	NOUN
admet-497	180	10	)	)	PUNCT
admet-497	180	11	.	.	PUNCT
admet-497	181	1	current	current	ADJ
admet-497	181	2	topics	topic	NOUN
admet-497	181	3	in	in	ADP
admet-497	181	4	medicinal	medicinal	ADJ
admet-497	181	5	chemistry	chemistry	NOUN
admet-497	181	6	1	1	NUM
admet-497	181	7	(	(	PUNCT
admet-497	181	8	2001	2001	NUM
admet-497	181	9	)	)	PUNCT
admet-497	181	10	277	277	NUM
admet-497	181	11	-	-	SYM
admet-497	181	12	351	351	NUM
admet-497	181	13	.	.	PUNCT
admet-497	182	1	[	[	X
admet-497	182	2	20	20	NUM
admet-497	182	3	]	]	PUNCT
admet-497	182	4	a.	a.	NOUN
admet-497	182	5	avdeef	avdeef	PROPN
admet-497	182	6	,	,	PUNCT
admet-497	182	7	e.	e.	PROPN
admet-497	182	8	fuguet	fuguet	PROPN
admet-497	182	9	,	,	PUNCT
admet-497	182	10	a.	a.	PROPN
admet-497	182	11	llinàs	llinàs	PROPN
admet-497	182	12	,	,	PUNCT
admet-497	182	13	c.	c.	PROPN
admet-497	182	14	ràfols	ràfols	PROPN
admet-497	182	15	,	,	PUNCT
admet-497	182	16	e.	e.	PROPN
admet-497	182	17	bosch	bosch	PROPN
admet-497	182	18	,	,	PUNCT
admet-497	182	19	g.	g.	PROPN
admet-497	182	20	völgyi	völgyi	PROPN
admet-497	182	21	,	,	PUNCT
admet-497	182	22	t.	t.	NOUN
admet-497	182	23	verbić	verbić	PROPN
admet-497	182	24	,	,	PUNCT
admet-497	182	25	e.	e.	PROPN
admet-497	182	26	boldyreva	boldyreva	PROPN
admet-497	182	27	,	,	PUNCT
admet-497	182	28	k.	k.	PROPN
admet-497	182	29	takácsnovác	takácsnovác	PROPN
admet-497	182	30	.	.	PUNCT
admet-497	183	1	equilibrium	equilibrium	NOUN
admet-497	183	2	solubility	solubility	NOUN
admet-497	183	3	measurement	measurement	NOUN
admet-497	183	4	of	of	ADP
admet-497	183	5	ionizable	ionizable	ADJ
admet-497	183	6	drugs	drug	NOUN
admet-497	183	7	–	–	PUNCT
admet-497	183	8	consensus	consensus	NOUN
admet-497	183	9	recommendations	recommendation	NOUN
admet-497	183	10	for	for	ADP
admet-497	183	11	improving	improve	VERB
admet-497	183	12	data	datum	NOUN
admet-497	183	13	quality	quality	NOUN
admet-497	183	14	.	.	PUNCT
admet-497	184	1	admet	admet	PROPN
admet-497	184	2	&	&	CCONJ
admet-497	184	3	dmpk	dmpk	PROPN
admet-497	184	4	4	4	NUM
admet-497	184	5	(	(	PUNCT
admet-497	184	6	2016	2016	NUM
admet-497	184	7	)	)	PUNCT
admet-497	184	8	117	117	NUM
admet-497	184	9	-	-	SYM
admet-497	184	10	178	178	NUM
admet-497	184	11	.	.	PUNCT
admet-497	185	1	[	[	X
admet-497	185	2	21	21	NUM
admet-497	185	3	]	]	X
admet-497	185	4	d.	d.	PROPN
admet-497	185	5	giron	giron	PROPN
admet-497	185	6	,	,	PUNCT
admet-497	185	7	d.j.w	d.j.w	PROPN
admet-497	185	8	.	.	PUNCT
admet-497	185	9	grant	grant	PROPN
admet-497	185	10	.	.	PUNCT
admet-497	186	1	evaluation	evaluation	NOUN
admet-497	186	2	of	of	ADP
admet-497	186	3	solid	solid	ADJ
admet-497	186	4	-	-	PUNCT
admet-497	186	5	state	state	NOUN
admet-497	186	6	properties	property	NOUN
admet-497	186	7	of	of	ADP
admet-497	186	8	salts	salt	NOUN
admet-497	186	9	(	(	PUNCT
admet-497	186	10	chapter	chapter	NOUN
admet-497	186	11	2	2	NUM
admet-497	186	12	)	)	PUNCT
admet-497	186	13	in	in	ADP
admet-497	186	14	:	:	PUNCT
admet-497	186	15	handbook	handbook	NOUN
admet-497	186	16	of	of	ADP
admet-497	186	17	pharmaceutical	pharmaceutical	ADJ
admet-497	186	18	salts	salt	NOUN
admet-497	186	19	.	.	PUNCT
admet-497	187	1	properties	property	NOUN
admet-497	187	2	,	,	PUNCT
admet-497	187	3	selection	selection	NOUN
admet-497	187	4	,	,	PUNCT
admet-497	187	5	and	and	CCONJ
admet-497	187	6	use	use	NOUN
admet-497	187	7	.	.	PUNCT
admet-497	188	1	p.	p.	NOUN
admet-497	188	2	h.	h.	PROPN
admet-497	188	3	stahl	stahl	PROPN
admet-497	188	4	,	,	PUNCT
admet-497	188	5	c.	c.	PROPN
admet-497	188	6	g.	g.	PROPN
admet-497	188	7	wermuth	wermuth	PROPN
admet-497	188	8	(	(	PUNCT
admet-497	188	9	eds	ed	NOUN
admet-497	188	10	.	.	PUNCT
admet-497	188	11	)	)	PUNCT
admet-497	188	12	.	.	PUNCT
admet-497	189	1	wiley	wiley	PROPN
admet-497	189	2	-	-	PUNCT
admet-497	189	3	vch	vch	PROPN
admet-497	189	4	,	,	PUNCT
admet-497	189	5	weinheim	weinheim	PROPN
admet-497	189	6	,	,	PUNCT
admet-497	189	7	germany	germany	PROPN
admet-497	189	8	,	,	PUNCT
admet-497	189	9	2002	2002	NUM
admet-497	189	10	,	,	PUNCT
admet-497	189	11	pp	pp	PROPN
admet-497	189	12	.	.	PUNCT
admet-497	190	1	19	19	NUM
admet-497	190	2	-	-	SYM
admet-497	190	3	40	40	NUM
admet-497	190	4	.	.	PUNCT
admet-497	191	1	[	[	X
admet-497	191	2	22	22	NUM
admet-497	191	3	]	]	PUNCT
admet-497	191	4	k.	k.	PROPN
admet-497	191	5	tackáks	tackáks	PROPN
admet-497	191	6	-	-	PUNCT
admet-497	191	7	novák	novák	NOUN
admet-497	191	8	,	,	PUNCT
admet-497	191	9	v.	v.	X
admet-497	191	10	szöke	szöke	PROPN
admet-497	191	11	,	,	PUNCT
admet-497	191	12	g.	g.	PROPN
admet-497	191	13	völgyi	völgyi	PROPN
admet-497	191	14	,	,	PUNCT
admet-497	191	15	p.	p.	NOUN
admet-497	191	16	horváth	horváth	PROPN
admet-497	191	17	,	,	PUNCT
admet-497	191	18	r.	r.	PROPN
admet-497	191	19	ambrus	ambrus	PROPN
admet-497	191	20	,	,	PUNCT
admet-497	191	21	p.	p.	PROPN
admet-497	191	22	szabó	szabó	PROPN
admet-497	191	23	-	-	PUNCT
admet-497	191	24	révész	révész	VERB
admet-497	191	25	.	.	PUNCT
admet-497	192	1	biorelevant	biorelevant	PROPN
admet-497	192	2	solubility	solubility	NOUN
admet-497	192	3	of	of	ADP
admet-497	192	4	poorly	poorly	ADV
admet-497	192	5	soluble	soluble	ADJ
admet-497	192	6	drugs	drug	NOUN
admet-497	192	7	:	:	PUNCT
admet-497	192	8	rivaroxaban	rivaroxaban	NOUN
admet-497	192	9	,	,	PUNCT
admet-497	192	10	furosemide	furosemide	ADJ
admet-497	192	11	,	,	PUNCT
admet-497	192	12	papaverine	papaverine	NOUN
admet-497	192	13	and	and	CCONJ
admet-497	192	14	niflumic	niflumic	ADJ
admet-497	192	15	acid	acid	NOUN
admet-497	192	16	.	.	PUNCT
admet-497	193	1	journal	journal	PROPN
admet-497	193	2	of	of	ADP
admet-497	193	3	pharmceutical	pharmceutical	ADJ
admet-497	193	4	and	and	CCONJ
admet-497	193	5	biomedical	biomedical	ADJ
admet-497	193	6	analysis	analysis	NOUN
admet-497	193	7	83	83	NUM
admet-497	193	8	(	(	PUNCT
admet-497	193	9	2013	2013	NUM
admet-497	193	10	)	)	PUNCT
admet-497	193	11	279	279	NUM
admet-497	193	12	-	-	SYM
admet-497	193	13	285	285	NUM
admet-497	193	14	.	.	PUNCT
admet-497	194	1	c.	c.	NOUN
admet-497	194	2	ràfols	ràfol	NOUN
admet-497	194	3	et	et	PROPN
admet-497	194	4	al	al	PROPN
admet-497	194	5	.	.	PROPN
admet-497	194	6	admet	admet	PROPN
admet-497	194	7	&	&	CCONJ
admet-497	194	8	dmpk	dmpk	PROPN
admet-497	194	9	6(1	6(1	NUM
admet-497	194	10	)	)	PUNCT
admet-497	194	11	(	(	PUNCT
admet-497	194	12	2018	2018	NUM
admet-497	194	13	)	)	PUNCT
admet-497	194	14	61	61	NUM
admet-497	194	15	-	-	SYM
admet-497	194	16	70	70	NUM
admet-497	194	17	70	70	NUM
admet-497	195	1	[	[	X
admet-497	195	2	23	23	NUM
admet-497	195	3	]	]	PUNCT
admet-497	195	4	j.	j.	PROPN
admet-497	195	5	fagerberg	fagerberg	PROPN
admet-497	195	6	,	,	PUNCT
admet-497	195	7	o.	o.	PROPN
admet-497	195	8	tsinman	tsinman	NOUN
admet-497	195	9	,	,	PUNCT
admet-497	195	10	n.	n.	PROPN
admet-497	195	11	sun	sun	PROPN
admet-497	195	12	,	,	PUNCT
admet-497	195	13	k.	k.	PROPN
admet-497	195	14	tsinman	tsinman	PROPN
admet-497	195	15	,	,	PUNCT
admet-497	195	16	a.	a.	NOUN
admet-497	195	17	avdeef	avdeef	PROPN
admet-497	195	18	,	,	PUNCT
admet-497	195	19	c.	c.	PROPN
admet-497	195	20	bergström	bergström	PROPN
admet-497	195	21	.	.	PUNCT
admet-497	196	1	dissolution	dissolution	NOUN
admet-497	196	2	rate	rate	NOUN
admet-497	196	3	and	and	CCONJ
admet-497	196	4	apparent	apparent	ADJ
admet-497	196	5	solubility	solubility	NOUN
admet-497	196	6	of	of	ADP
admet-497	196	7	poorly	poorly	ADV
admet-497	196	8	soluble	soluble	ADJ
admet-497	196	9	drugs	drug	NOUN
admet-497	196	10	in	in	ADP
admet-497	196	11	biorelevant	biorelevant	ADJ
admet-497	196	12	dissolution	dissolution	NOUN
admet-497	196	13	media	medium	NOUN
admet-497	196	14	.	.	PUNCT
admet-497	197	1	molecular	molecular	ADJ
admet-497	197	2	pharmacy	pharmacy	NOUN
admet-497	197	3	7	7	NUM
admet-497	197	4	(	(	PUNCT
admet-497	197	5	2010	2010	NUM
admet-497	197	6	)	)	PUNCT
admet-497	197	7	1419	1419	NUM
admet-497	197	8	-	-	SYM
admet-497	197	9	1430	1430	NUM
admet-497	197	10	.	.	PUNCT
admet-497	198	1	[	[	X
admet-497	198	2	24	24	NUM
admet-497	198	3	]	]	X
admet-497	198	4	g.	g.	PROPN
admet-497	198	5	ottaviani	ottaviani	PROPN
admet-497	198	6	,	,	PUNCT
admet-497	198	7	d.	d.	PROPN
admet-497	198	8	gosling	gosling	PROPN
admet-497	198	9	,	,	PUNCT
admet-497	198	10	c.	c.	PROPN
admet-497	198	11	patissier	patissier	PROPN
admet-497	198	12	,	,	PUNCT
admet-497	198	13	s.	s.	PROPN
admet-497	198	14	rodde	rodde	PROPN
admet-497	198	15	,	,	PUNCT
admet-497	198	16	l.	l.	PROPN
admet-497	198	17	zhou	zhou	PROPN
admet-497	198	18	,	,	PUNCT
admet-497	198	19	b.	b.	PROPN
admet-497	198	20	faller	faller	PROPN
admet-497	198	21	.	.	PUNCT
admet-497	199	1	what	what	PRON
admet-497	199	2	is	be	AUX
admet-497	199	3	modulating	modulate	VERB
admet-497	199	4	solubility	solubility	NOUN
admet-497	199	5	in	in	ADP
admet-497	199	6	simulated	simulated	ADJ
admet-497	199	7	intestinal	intestinal	ADJ
admet-497	199	8	fluids	fluid	NOUN
admet-497	199	9	?	?	PUNCT
admet-497	200	1	european	european	ADJ
admet-497	200	2	journal	journal	PROPN
admet-497	200	3	of	of	ADP
admet-497	200	4	pharmceutical	pharmceutical	ADJ
admet-497	200	5	sciencies	sciencie	NOUN
admet-497	200	6	41	41	NUM
admet-497	200	7	(	(	PUNCT
admet-497	200	8	2010	2010	NUM
admet-497	200	9	)	)	PUNCT
admet-497	200	10	452	452	NUM
admet-497	200	11	-	-	SYM
admet-497	200	12	457	457	NUM
admet-497	200	13	.	.	PUNCT
admet-497	201	1	©	©	SYM
admet-497	201	2	2018	2018	NUM
admet-497	201	3	by	by	ADP
admet-497	201	4	the	the	DET
admet-497	201	5	authors	author	NOUN
admet-497	201	6	;	;	PUNCT
admet-497	202	1	licensee	licensee	PROPN
admet-497	202	2	iapc	iapc	PROPN
admet-497	202	3	,	,	PUNCT
admet-497	202	4	zagreb	zagreb	PROPN
admet-497	202	5	,	,	PUNCT
admet-497	202	6	croatia	croatia	PROPN
admet-497	202	7	.	.	PUNCT
admet-497	203	1	this	this	DET
admet-497	203	2	article	article	NOUN
admet-497	203	3	is	be	AUX
admet-497	203	4	an	an	DET
admet-497	203	5	open	open	ADJ
admet-497	203	6	-	-	PUNCT
admet-497	203	7	access	access	NOUN
admet-497	203	8	article	article	NOUN
admet-497	203	9	distributed	distribute	VERB
admet-497	203	10	under	under	ADP
admet-497	203	11	the	the	DET
admet-497	203	12	terms	term	NOUN
admet-497	203	13	and	and	CCONJ
admet-497	203	14	conditions	condition	NOUN
admet-497	203	15	of	of	ADP
admet-497	203	16	the	the	DET
admet-497	203	17	creative	creative	ADJ
admet-497	203	18	commons	common	NOUN
admet-497	203	19	attribution	attribution	NOUN
admet-497	203	20	license	license	NOUN
admet-497	203	21	(	(	PUNCT
admet-497	203	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-497	203	23	)	)	PUNCT
admet-497	203	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN