id	sid	tid	token	lemma	pos
admet-505	1	1	cocrystal	cocrystal	PROPN
admet-505	1	2	solubility	solubility	NOUN
admet-505	1	3	-	-	PUNCT
admet-505	1	4	ph	ph	ADJ
admet-505	1	5	and	and	CCONJ
admet-505	1	6	drug	drug	NOUN
admet-505	1	7	solubilization	solubilization	NOUN
admet-505	1	8	capacity	capacity	NOUN
admet-505	1	9	of	of	ADP
admet-505	1	10	sodium	sodium	NOUN
admet-505	1	11	sodecyl	sodecyl	NOUN
admet-505	1	12	sulfate	sulfate	VERB
admet-505	1	13	–	–	PUNCT
admet-505	1	14	mass	mass	NOUN
admet-505	1	15	action	action	NOUN
admet-505	1	16	model	model	NOUN
admet-505	1	17	for	for	ADP
admet-505	1	18	data	datum	NOUN
admet-505	1	19	analysis	analysis	NOUN
admet-505	1	20	and	and	CCONJ
admet-505	1	21	simulation	simulation	NOUN
admet-505	1	22	to	to	PART
admet-505	1	23	improve	improve	VERB
admet-505	1	24	design	design	NOUN
admet-505	1	25	of	of	ADP
admet-505	1	26	experiments	experiment	NOUN
admet-505	1	27	doi	doi	NOUN
admet-505	1	28	:	:	PUNCT
admet-505	1	29	10.5599	10.5599	NUM
admet-505	1	30	/	/	SYM
admet-505	1	31	admet.505	admet.505	PROPN
admet-505	1	32	105	105	NUM
admet-505	1	33	admet	admet	PROPN
admet-505	1	34	&	&	CCONJ
admet-505	1	35	dmpk	dmpk	PROPN
admet-505	1	36	6(2	6(2	NUM
admet-505	1	37	)	)	PUNCT
admet-505	1	38	(	(	PUNCT
admet-505	1	39	2018	2018	NUM
admet-505	1	40	)	)	PUNCT
admet-505	1	41	105	105	NUM
admet-505	1	42	-	-	SYM
admet-505	1	43	139	139	NUM
admet-505	1	44	;	;	PUNCT
admet-505	1	45	doi	doi	NOUN
admet-505	1	46	:	:	PUNCT
admet-505	1	47	http://dx.doi.org/10.5599/admet.505	http://dx.doi.org/10.5599/admet.505	PROPN
admet-505	1	48	open	open	ADJ
admet-505	1	49	access	access	NOUN
admet-505	1	50	:	:	PUNCT
admet-505	1	51	issn	issn	PROPN
admet-505	1	52	:	:	PUNCT
admet-505	1	53	1848	1848	NUM
admet-505	1	54	-	-	SYM
admet-505	1	55	7718	7718	NUM
admet-505	1	56	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-505	1	57	review	review	NOUN
admet-505	1	58	cocrystal	cocrystal	PROPN
admet-505	1	59	solubility	solubility	NOUN
admet-505	1	60	-	-	PUNCT
admet-505	1	61	ph	ph	ADJ
admet-505	1	62	and	and	CCONJ
admet-505	1	63	drug	drug	NOUN
admet-505	1	64	solubilization	solubilization	NOUN
admet-505	1	65	capacity	capacity	NOUN
admet-505	1	66	of	of	ADP
admet-505	1	67	sodium	sodium	NOUN
admet-505	1	68	dodecyl	dodecyl	NOUN
admet-505	1	69	sulfate	sulfate	VERB
admet-505	1	70	–	–	PUNCT
admet-505	1	71	mass	mass	NOUN
admet-505	1	72	action	action	NOUN
admet-505	1	73	model	model	NOUN
admet-505	1	74	for	for	ADP
admet-505	1	75	data	datum	NOUN
admet-505	1	76	analysis	analysis	NOUN
admet-505	1	77	and	and	CCONJ
admet-505	1	78	simulation	simulation	NOUN
admet-505	1	79	to	to	PART
admet-505	1	80	improve	improve	VERB
admet-505	1	81	design	design	NOUN
admet-505	1	82	of	of	ADP
admet-505	1	83	experiments	experiment	NOUN
admet-505	1	84	alex	alex	PROPN
admet-505	1	85	avdeef	avdeef	PROPN
admet-505	1	86	in	in	ADP
admet-505	1	87	-	-	PUNCT
admet-505	1	88	adme	adme	NOUN
admet-505	1	89	research	research	NOUN
admet-505	1	90	,	,	PUNCT
admet-505	1	91	1732	1732	NUM
admet-505	1	92	first	first	ADJ
admet-505	1	93	avenue	avenue	PROPN
admet-505	1	94	#	#	SYM
admet-505	1	95	102	102	NUM
admet-505	1	96	,	,	PUNCT
admet-505	1	97	new	new	PROPN
admet-505	1	98	york	york	PROPN
admet-505	1	99	,	,	PUNCT
admet-505	1	100	ny	ny	PROPN
admet-505	1	101	10128	10128	NUM
admet-505	1	102	usa	usa	PROPN
admet-505	1	103	e	e	PROPN
admet-505	1	104	-	-	NOUN
admet-505	1	105	mail	mail	NOUN
admet-505	1	106	:	:	PUNCT
admet-505	1	107	alex@in-adme.com	alex@in-adme.com	NOUN
admet-505	1	108	;	;	PUNCT
admet-505	1	109	tel	tel	PROPN
admet-505	1	110	.	.	PUNCT
admet-505	1	111	:	:	PUNCT
admet-505	2	1	+1	+1	PROPN
admet-505	2	2	-	-	PUNCT
admet-505	2	3	646	646	NUM
admet-505	2	4	-	-	PUNCT
admet-505	2	5	678	678	NUM
admet-505	2	6	-	-	SYM
admet-505	2	7	5713	5713	NUM
admet-505	2	8	received	receive	VERB
admet-505	2	9	:	:	PUNCT
admet-505	2	10	february	february	PROPN
admet-505	2	11	07	07	NUM
admet-505	2	12	,	,	PUNCT
admet-505	2	13	2018	2018	NUM
admet-505	2	14	;	;	PUNCT
admet-505	2	15	revised	revise	VERB
admet-505	2	16	:	:	PUNCT
admet-505	2	17	march	march	PROPN
admet-505	2	18	30	30	NUM
admet-505	2	19	,	,	PUNCT
admet-505	2	20	2018	2018	NUM
admet-505	2	21	;	;	PUNCT
admet-505	2	22	available	available	ADJ
admet-505	2	23	online	online	NOUN
admet-505	2	24	:	:	PUNCT
admet-505	2	25	april	april	PROPN
admet-505	2	26	22	22	NUM
admet-505	2	27	,	,	PUNCT
admet-505	2	28	2018	2018	NUM
admet-505	2	29	_	_	PUNCT
admet-505	3	1	_	_	PUNCT
admet-505	4	1	_	_	PUNCT
admet-505	5	1	_	_	PUNCT
admet-505	6	1	_	_	PUNCT
admet-505	7	1	_	_	PUNCT
admet-505	8	1	_	_	PUNCT
admet-505	9	1	_	_	PUNCT
admet-505	10	1	_	_	PUNCT
admet-505	11	1	_	_	PUNCT
admet-505	12	1	_	_	PUNCT
admet-505	13	1	_	_	PUNCT
admet-505	14	1	_	_	PUNCT
admet-505	15	1	_	_	PUNCT
admet-505	16	1	_	_	PUNCT
admet-505	17	1	_	_	PUNCT
admet-505	18	1	_	_	PUNCT
admet-505	19	1	_	_	PUNCT
admet-505	20	1	_	_	PUNCT
admet-505	21	1	_	_	PUNCT
admet-505	22	1	_	_	PUNCT
admet-505	23	1	_	_	PUNCT
admet-505	24	1	_	_	PUNCT
admet-505	25	1	_	_	PUNCT
admet-505	26	1	_	_	PUNCT
admet-505	27	1	_	_	PUNCT
admet-505	28	1	_	_	PUNCT
admet-505	29	1	_	_	PUNCT
admet-505	30	1	_	_	PUNCT
admet-505	31	1	_	_	PUNCT
admet-505	32	1	_	_	PUNCT
admet-505	33	1	_	_	PUNCT
admet-505	34	1	_	_	PUNCT
admet-505	35	1	_	_	PUNCT
admet-505	36	1	_	_	PUNCT
admet-505	37	1	_	_	PUNCT
admet-505	38	1	_	_	PUNCT
admet-505	39	1	_	_	PUNCT
admet-505	40	1	_	_	PUNCT
admet-505	41	1	_	_	PUNCT
admet-505	42	1	_	_	PUNCT
admet-505	43	1	_	_	PUNCT
admet-505	44	1	_	_	PUNCT
admet-505	45	1	_	_	PUNCT
admet-505	46	1	_	_	PUNCT
admet-505	47	1	_	_	PUNCT
admet-505	48	1	_	_	PUNCT
admet-505	49	1	_	_	PUNCT
admet-505	50	1	_	_	PUNCT
admet-505	51	1	_	_	PUNCT
admet-505	52	1	_	_	PUNCT
admet-505	53	1	_	_	PUNCT
admet-505	54	1	_	_	PUNCT
admet-505	55	1	_	_	PUNCT
admet-505	56	1	_	_	PUNCT
admet-505	57	1	_	_	PUNCT
admet-505	58	1	_	_	PUNCT
admet-505	59	1	_	_	PUNCT
admet-505	60	1	_	_	PUNCT
admet-505	61	1	_	_	PUNCT
admet-505	62	1	_	_	PUNCT
admet-505	63	1	_	_	PUNCT
admet-505	64	1	_	_	PUNCT
admet-505	65	1	_	_	PUNCT
admet-505	66	1	_	_	PUNCT
admet-505	67	1	_	_	PUNCT
admet-505	68	1	_	_	PUNCT
admet-505	69	1	_	_	PUNCT
admet-505	70	1	_	_	PUNCT
admet-505	71	1	_	_	PUNCT
admet-505	72	1	_	_	PUNCT
admet-505	73	1	_	_	PUNCT
admet-505	74	1	_	_	PUNCT
admet-505	75	1	_	_	PUNCT
admet-505	76	1	_	_	PUNCT
admet-505	77	1	_	_	PUNCT
admet-505	78	1	_	_	PUNCT
admet-505	79	1	_	_	PUNCT
admet-505	80	1	_	_	PUNCT
admet-505	81	1	_	_	PUNCT
admet-505	82	1	_	_	PUNCT
admet-505	83	1	_	_	PUNCT
admet-505	84	1	_	_	PUNCT
admet-505	85	1	_	_	PUNCT
admet-505	86	1	_	_	PUNCT
admet-505	87	1	_	_	PUNCT
admet-505	88	1	_	_	PUNCT
admet-505	89	1	_	_	PUNCT
admet-505	90	1	_	_	PUNCT
admet-505	91	1	_	_	PUNCT
admet-505	92	1	_	_	PUNCT
admet-505	93	1	_	_	PUNCT
admet-505	94	1	_	_	PUNCT
admet-505	95	1	_	_	PUNCT
admet-505	96	1	_	_	PUNCT
admet-505	97	1	_	_	PUNCT
admet-505	98	1	_	_	PUNCT
admet-505	99	1	_	_	PUNCT
admet-505	100	1	_	_	PUNCT
admet-505	101	1	_	_	PUNCT
admet-505	102	1	_	_	PUNCT
admet-505	103	1	_	_	PUNCT
admet-505	104	1	_	_	PUNCT
admet-505	105	1	_	_	PUNCT
admet-505	106	1	_	_	PUNCT
admet-505	107	1	_	_	PUNCT
admet-505	108	1	_	_	PUNCT
admet-505	109	1	_	_	PUNCT
admet-505	110	1	abstract	abstract	ADV
admet-505	110	2	this	this	DET
admet-505	110	3	review	review	NOUN
admet-505	110	4	discusses	discuss	VERB
admet-505	110	5	the	the	DET
admet-505	110	6	disposition	disposition	NOUN
admet-505	110	7	of	of	ADP
admet-505	110	8	the	the	DET
admet-505	110	9	anionic	anionic	ADJ
admet-505	110	10	surfactant	surfactant	NOUN
admet-505	110	11	,	,	PUNCT
admet-505	110	12	sodium	sodium	NOUN
admet-505	110	13	dodecyl	dodecyl	NOUN
admet-505	110	14	sulfate	sulfate	NOUN
admet-505	110	15	(	(	PUNCT
admet-505	110	16	sds	sds	NOUN
admet-505	110	17	;	;	PUNCT
admet-505	110	18	i.e.	i.e.	X
admet-505	110	19	,	,	PUNCT
admet-505	110	20	sodium	sodium	NOUN
admet-505	110	21	lauryl	lauryl	NOUN
admet-505	110	22	sulfate	sulfate	NOUN
admet-505	110	23	)	)	PUNCT
admet-505	110	24	,	,	PUNCT
admet-505	110	25	to	to	PART
admet-505	110	26	solubilize	solubilize	VERB
admet-505	110	27	sparingly	sparingly	ADV
admet-505	110	28	-	-	PUNCT
admet-505	110	29	soluble	soluble	ADJ
admet-505	110	30	drugs	drug	NOUN
admet-505	110	31	above	above	ADP
admet-505	110	32	the	the	DET
admet-505	110	33	surfactant	surfactant	ADJ
admet-505	110	34	critical	critical	ADJ
admet-505	110	35	micelle	micelle	NOUN
admet-505	110	36	concentration	concentration	NOUN
admet-505	110	37	(	(	PUNCT
admet-505	110	38	cmc	cmc	NOUN
admet-505	110	39	)	)	PUNCT
admet-505	110	40	,	,	PUNCT
admet-505	110	41	as	as	SCONJ
admet-505	110	42	quantitated	quantitate	VERB
admet-505	110	43	by	by	ADP
admet-505	110	44	the	the	DET
admet-505	110	45	solubilization	solubilization	NOUN
admet-505	110	46	capacity	capacity	NOUN
admet-505	110	47	(	(	PUNCT
admet-505	110	48	k	k	NOUN
admet-505	110	49	)	)	PUNCT
admet-505	110	50	.	.	PUNCT
admet-505	111	1	a	a	DET
admet-505	111	2	compilation	compilation	NOUN
admet-505	111	3	of	of	ADP
admet-505	111	4	101	101	NUM
admet-505	111	5	published	publish	VERB
admet-505	111	6	sds	sds	PROPN
admet-505	111	7	k	k	PROPN
admet-505	111	8	values	value	NOUN
admet-505	111	9	of	of	ADP
admet-505	111	10	mostly	mostly	ADV
admet-505	111	11	poorly	poorly	ADV
admet-505	111	12	-	-	PUNCT
admet-505	111	13	soluble	soluble	ADJ
admet-505	111	14	drug	drug	NOUN
admet-505	111	15	molecules	molecule	NOUN
admet-505	111	16	was	be	AUX
admet-505	111	17	used	use	VERB
admet-505	111	18	to	to	PART
admet-505	111	19	develop	develop	VERB
admet-505	111	20	a	a	DET
admet-505	111	21	prediction	prediction	NOUN
admet-505	111	22	model	model	NOUN
admet-505	111	23	as	as	ADP
admet-505	111	24	a	a	DET
admet-505	111	25	function	function	NOUN
admet-505	111	26	of	of	ADP
admet-505	111	27	the	the	DET
admet-505	111	28	drug	drug	NOUN
admet-505	111	29	’s	’s	PART
admet-505	111	30	intrinsic	intrinsic	ADJ
admet-505	111	31	solubility	solubility	NOUN
admet-505	111	32	,	,	PUNCT
admet-505	111	33	s0	s0	PROPN
admet-505	111	34	,	,	PUNCT
admet-505	111	35	and	and	CCONJ
admet-505	111	36	its	its	PRON
admet-505	111	37	calculated	calculated	ADJ
admet-505	111	38	h	h	NOUN
admet-505	111	39	-	-	PUNCT
admet-505	111	40	bond	bond	NOUN
admet-505	111	41	acceptor	acceptor	NOUN
admet-505	111	42	/	/	SYM
admet-505	111	43	donor	donor	NOUN
admet-505	111	44	potential	potential	NOUN
admet-505	111	45	.	.	PUNCT
admet-505	112	1	in	in	ADP
admet-505	112	2	almost	almost	ADV
admet-505	112	3	all	all	PRON
admet-505	112	4	cases	case	NOUN
admet-505	112	5	,	,	PUNCT
admet-505	112	6	the	the	DET
admet-505	112	7	surfactant	surfactant	NOUN
admet-505	112	8	was	be	AUX
admet-505	112	9	found	find	VERB
admet-505	112	10	to	to	PART
admet-505	112	11	solubilize	solubilize	VERB
admet-505	112	12	the	the	DET
admet-505	112	13	neutral	neutral	ADJ
admet-505	112	14	form	form	NOUN
admet-505	112	15	of	of	ADP
admet-505	112	16	the	the	DET
admet-505	112	17	drug	drug	NOUN
admet-505	112	18	.	.	PUNCT
admet-505	113	1	using	use	VERB
admet-505	113	2	the	the	DET
admet-505	113	3	mass	mass	ADJ
admet-505	113	4	action	action	NOUN
admet-505	113	5	model	model	NOUN
admet-505	113	6	,	,	PUNCT
admet-505	113	7	the	the	DET
admet-505	113	8	k	k	PROPN
admet-505	113	9	values	value	NOUN
admet-505	113	10	were	be	AUX
admet-505	113	11	converted	convert	VERB
admet-505	113	12	to	to	ADP
admet-505	113	13	drug	drug	NOUN
admet-505	113	14	-	-	PUNCT
admet-505	113	15	micelle	micelle	NOUN
admet-505	113	16	stoichiometric	stoichiometric	ADJ
admet-505	113	17	binding	binding	ADJ
admet-505	113	18	constants	constant	NOUN
admet-505	113	19	,	,	PUNCT
admet-505	113	20	kn	kn	PROPN
admet-505	113	21	,	,	PUNCT
admet-505	113	22	corresponding	correspond	VERB
admet-505	113	23	to	to	ADP
admet-505	113	24	drug	drug	NOUN
admet-505	113	25	-	-	PUNCT
admet-505	113	26	micelle	micelle	NOUN
admet-505	113	27	equilibria	equilibrium	NOUN
admet-505	113	28	in	in	ADP
admet-505	113	29	drug	drug	NOUN
admet-505	113	30	-	-	PUNCT
admet-505	113	31	saturated	saturate	VERB
admet-505	113	32	solutions	solution	NOUN
admet-505	113	33	.	.	PUNCT
admet-505	114	1	an	an	DET
admet-505	114	2	in	in	ADP
admet-505	114	3	-	-	PUNCT
admet-505	114	4	depth	depth	NOUN
admet-505	114	5	case	case	NOUN
admet-505	114	6	study	study	NOUN
admet-505	114	7	(	(	PUNCT
admet-505	114	8	data	datum	NOUN
admet-505	114	9	from	from	ADP
admet-505	114	10	published	publish	VERB
admet-505	114	11	sources	source	NOUN
admet-505	114	12	)	)	PUNCT
admet-505	114	13	considered	consider	VERB
admet-505	114	14	the	the	DET
admet-505	114	15	micellization	micellization	NOUN
admet-505	114	16	reactions	reaction	NOUN
admet-505	114	17	as	as	ADP
admet-505	114	18	a	a	DET
admet-505	114	19	function	function	NOUN
admet-505	114	20	of	of	ADP
admet-505	114	21	ph	ph	NOUN
admet-505	114	22	of	of	ADP
admet-505	114	23	a	a	DET
admet-505	114	24	weak	weak	ADJ
admet-505	114	25	base	base	NOUN
admet-505	114	26	,	,	PUNCT
admet-505	114	27	b	b	NOUN
admet-505	114	28	,	,	PUNCT
admet-505	114	29	(	(	PUNCT
admet-505	114	30	pka	pka	PROPN
admet-505	114	31	3.58	3.58	NUM
admet-505	114	32	,	,	PUNCT
admet-505	114	33	s0	s0	PROPN
admet-505	114	34	52	52	NUM
admet-505	114	35	μg	μg	NOUN
admet-505	114	36	/	/	SYM
admet-505	114	37	ml	ml	NOUN
admet-505	114	38	)	)	PUNCT
admet-505	114	39	,	,	PUNCT
admet-505	114	40	where	where	SCONJ
admet-505	114	41	at	at	ADP
admet-505	114	42	ph	ph	PROPN
admet-505	114	43	1	1	NUM
admet-505	114	44	the	the	DET
admet-505	114	45	bh.sds	bh.sds	NOUN
admet-505	114	46	salt	salt	NOUN
admet-505	114	47	was	be	AUX
admet-505	114	48	predicted	predict	VERB
admet-505	114	49	to	to	PART
admet-505	114	50	precipitate	precipitate	VERB
admet-505	114	51	both	both	PRON
admet-505	114	52	below	below	ADP
admet-505	114	53	and	and	CCONJ
admet-505	114	54	above	above	ADP
admet-505	114	55	the	the	DET
admet-505	114	56	cmc	cmc	NOUN
admet-505	114	57	.	.	PUNCT
admet-505	115	1	at	at	ADP
admet-505	115	2	low	low	PROPN
admet-505	115	3	sds	sds	PROPN
admet-505	115	4	concentrations	concentration	NOUN
admet-505	115	5	,	,	PUNCT
admet-505	115	6	two	two	NUM
admet-505	115	7	drug	drug	NOUN
admet-505	115	8	salts	salt	NOUN
admet-505	115	9	were	be	AUX
admet-505	115	10	predicted	predict	VERB
admet-505	115	11	to	to	AUX
admet-505	115	12	co	co	VERB
admet-505	115	13	-	-	VERB
admet-505	115	14	precipitate	precipitate	ADJ
admet-505	115	15	:	:	PUNCT
admet-505	115	16	bh.cl	bh.cl	NOUN
admet-505	115	17	and	and	CCONJ
admet-505	115	18	bh.sds	bh.sds	PROPN
admet-505	115	19	.	.	PUNCT
admet-505	116	1	solubility	solubility	NOUN
admet-505	116	2	products	product	NOUN
admet-505	116	3	of	of	ADP
admet-505	116	4	both	both	PRON
admet-505	116	5	were	be	AUX
admet-505	116	6	determined	determine	VERB
admet-505	116	7	from	from	ADP
admet-505	116	8	the	the	DET
admet-505	116	9	analysis	analysis	NOUN
admet-505	116	10	of	of	ADP
admet-505	116	11	the	the	DET
admet-505	116	12	reported	report	VERB
admet-505	116	13	solubility	solubility	NOUN
admet-505	116	14	-	-	PUNCT
admet-505	116	15	surfactant	surfactant	NOUN
admet-505	116	16	data	datum	NOUN
admet-505	116	17	.	.	PUNCT
admet-505	117	1	above	above	ADP
admet-505	117	2	the	the	DET
admet-505	117	3	cmc	cmc	NOUN
admet-505	117	4	,	,	PUNCT
admet-505	117	5	in	in	ADP
admet-505	117	6	a	a	DET
admet-505	117	7	rare	rare	ADJ
admet-505	117	8	example	example	NOUN
admet-505	117	9	,	,	PUNCT
admet-505	117	10	the	the	DET
admet-505	117	11	charged	charge	VERB
admet-505	117	12	form	form	NOUN
admet-505	117	13	of	of	ADP
admet-505	117	14	the	the	DET
admet-505	117	15	drug	drug	NOUN
admet-505	117	16	(	(	PUNCT
admet-505	117	17	bh	bh	NOUN
admet-505	117	18	+	+	CCONJ
admet-505	117	19	)	)	PUNCT
admet-505	117	20	appeared	appear	VERB
admet-505	117	21	to	to	PART
admet-505	117	22	be	be	AUX
admet-505	117	23	strongly	strongly	ADV
admet-505	117	24	solubilized	solubilize	VERB
admet-505	117	25	by	by	ADP
admet-505	117	26	the	the	DET
admet-505	117	27	surfactant	surfactant	NOUN
admet-505	117	28	.	.	PUNCT
admet-505	118	1	the	the	DET
admet-505	118	2	constant	constant	ADJ
admet-505	118	3	for	for	ADP
admet-505	118	4	that	that	DET
admet-505	118	5	reaction	reaction	NOUN
admet-505	118	6	was	be	AUX
admet-505	118	7	also	also	ADV
admet-505	118	8	determined	determine	VERB
admet-505	118	9	.	.	PUNCT
admet-505	119	1	at	at	ADP
admet-505	119	2	ph	ph	PROPN
admet-505	119	3	7	7	NUM
admet-505	119	4	,	,	PUNCT
admet-505	119	5	the	the	DET
admet-505	119	6	reactions	reaction	NOUN
admet-505	119	7	were	be	AUX
admet-505	119	8	simpler	simple	ADJ
admet-505	119	9	,	,	PUNCT
admet-505	119	10	as	as	SCONJ
admet-505	119	11	only	only	ADV
admet-505	119	12	the	the	DET
admet-505	119	13	neutral	neutral	ADJ
admet-505	119	14	form	form	NOUN
admet-505	119	15	of	of	ADP
admet-505	119	16	the	the	DET
admet-505	119	17	drug	drug	NOUN
admet-505	119	18	was	be	AUX
admet-505	119	19	solubilized	solubilize	VERB
admet-505	119	20	,	,	PUNCT
admet-505	119	21	to	to	ADP
admet-505	119	22	a	a	DET
admet-505	119	23	significantly	significantly	ADV
admet-505	119	24	lesser	less	ADJ
admet-505	119	25	extent	extent	NOUN
admet-505	119	26	than	than	ADP
admet-505	119	27	at	at	ADP
admet-505	119	28	ph	ph	ADJ
admet-505	119	29	1	1	NUM
admet-505	119	30	.	.	PUNCT
admet-505	119	31	case	case	NOUN
admet-505	119	32	studies	study	NOUN
admet-505	119	33	also	also	ADV
admet-505	119	34	featured	feature	VERB
admet-505	119	35	examples	example	NOUN
admet-505	119	36	of	of	ADP
admet-505	119	37	solubilization	solubilization	NOUN
admet-505	119	38	of	of	ADP
admet-505	119	39	solids	solid	NOUN
admet-505	119	40	in	in	ADP
admet-505	119	41	the	the	DET
admet-505	119	42	form	form	NOUN
admet-505	119	43	of	of	ADP
admet-505	119	44	cocrystals	cocrystal	NOUN
admet-505	119	45	.	.	PUNCT
admet-505	120	1	for	for	ADP
admet-505	120	2	many	many	ADJ
admet-505	120	3	cocrystal	cocrystal	ADJ
admet-505	120	4	systems	system	NOUN
admet-505	120	5	studied	study	VERB
admet-505	120	6	in	in	ADP
admet-505	120	7	aqueous	aqueous	ADJ
admet-505	120	8	solution	solution	NOUN
admet-505	120	9	,	,	PUNCT
admet-505	120	10	the	the	DET
admet-505	120	11	anticipated	anticipate	VERB
admet-505	120	12	supersaturated	supersaturated	ADJ
admet-505	120	13	state	state	NOUN
admet-505	120	14	is	be	AUX
admet-505	120	15	not	not	PART
admet-505	120	16	long	long	ADV
admet-505	120	17	-	-	PUNCT
admet-505	120	18	lasting	last	VERB
admet-505	120	19	,	,	PUNCT
admet-505	120	20	as	as	SCONJ
admet-505	120	21	the	the	DET
admet-505	120	22	drug	drug	NOUN
admet-505	120	23	component	component	NOUN
admet-505	120	24	precipitates	precipitate	NOUN
admet-505	120	25	to	to	ADP
admet-505	120	26	a	a	DET
admet-505	120	27	thermodynamically	thermodynamically	ADV
admet-505	120	28	stable	stable	ADJ
admet-505	120	29	form	form	NOUN
admet-505	120	30	,	,	PUNCT
admet-505	120	31	thus	thus	ADV
admet-505	120	32	lowering	lower	VERB
admet-505	120	33	the	the	DET
admet-505	120	34	amount	amount	NOUN
admet-505	120	35	of	of	ADP
admet-505	120	36	the	the	DET
admet-505	120	37	active	active	ADJ
admet-505	120	38	ingredient	ingredient	NOUN
admet-505	120	39	available	available	ADJ
admet-505	120	40	for	for	ADP
admet-505	120	41	intestinal	intestinal	ADJ
admet-505	120	42	absorption	absorption	NOUN
admet-505	120	43	.	.	PUNCT
admet-505	121	1	use	use	NOUN
admet-505	121	2	of	of	ADP
admet-505	121	3	surfactant	surfactant	NOUN
admet-505	121	4	can	can	AUX
admet-505	121	5	prevent	prevent	VERB
admet-505	121	6	this	this	PRON
admet-505	121	7	.	.	PUNCT
admet-505	122	1	a	a	DET
admet-505	122	2	recently	recently	ADV
admet-505	122	3	-	-	PUNCT
admet-505	122	4	described	describe	VERB
admet-505	122	5	method	method	NOUN
admet-505	122	6	for	for	ADP
admet-505	122	7	predicting	predict	VERB
admet-505	122	8	the	the	DET
admet-505	122	9	solubility	solubility	NOUN
admet-505	122	10	product	product	NOUN
admet-505	122	11	of	of	ADP
admet-505	122	12	cocrystals	cocrystal	NOUN
admet-505	122	13	(	(	PUNCT
admet-505	122	14	coupled	couple	VERB
admet-505	122	15	with	with	ADP
admet-505	122	16	predicted	predict	VERB
admet-505	122	17	k	k	PROPN
admet-505	122	18	values	value	NOUN
admet-505	122	19	described	describe	VERB
admet-505	122	20	here	here	ADV
admet-505	122	21	)	)	PUNCT
admet-505	122	22	allowed	allow	VERB
admet-505	122	23	for	for	ADP
admet-505	122	24	simulations	simulation	NOUN
admet-505	122	25	of	of	ADP
admet-505	122	26	solubilityph	solubilityph	ADJ
admet-505	122	27	speciation	speciation	NOUN
admet-505	122	28	profiles	profile	NOUN
admet-505	122	29	of	of	ADP
admet-505	122	30	cocrystal	cocrystal	ADJ
admet-505	122	31	systems	system	NOUN
admet-505	122	32	in	in	ADP
admet-505	122	33	the	the	DET
admet-505	122	34	presence	presence	NOUN
admet-505	122	35	of	of	ADP
admet-505	122	36	sds	sds	PROPN
admet-505	122	37	.	.	PUNCT
admet-505	123	1	well	well	INTJ
admet-505	123	2	in	in	ADP
admet-505	123	3	advance	advance	NOUN
admet-505	123	4	of	of	ADP
admet-505	123	5	any	any	DET
admet-505	123	6	actual	actual	ADJ
admet-505	123	7	measurements	measurement	NOUN
admet-505	123	8	,	,	PUNCT
admet-505	123	9	these	these	DET
admet-505	123	10	simulations	simulation	NOUN
admet-505	123	11	can	can	AUX
admet-505	123	12	be	be	AUX
admet-505	123	13	used	use	VERB
admet-505	123	14	to	to	PART
admet-505	123	15	probe	probe	VERB
admet-505	123	16	conditions	condition	NOUN
admet-505	123	17	favorable	favorable	ADJ
admet-505	123	18	to	to	ADP
admet-505	123	19	the	the	DET
admet-505	123	20	design	design	NOUN
admet-505	123	21	of	of	ADP
admet-505	123	22	cocrystal	cocrystal	ADJ
admet-505	123	23	experiments	experiment	NOUN
admet-505	123	24	where	where	SCONJ
admet-505	123	25	sds	sds	PROPN
admet-505	123	26	stabilizes	stabilize	VERB
admet-505	123	27	cocrystal	cocrystal	ADJ
admet-505	123	28	suspensions	suspension	NOUN
admet-505	123	29	against	against	ADP
admet-505	123	30	drug	drug	NOUN
admet-505	123	31	precipitation	precipitation	NOUN
admet-505	123	32	over	over	ADP
admet-505	123	33	a	a	DET
admet-505	123	34	predicted	predict	VERB
admet-505	123	35	range	range	NOUN
admet-505	123	36	of	of	ADP
admet-505	123	37	ph	ph	ADJ
admet-505	123	38	values	value	NOUN
admet-505	123	39	.	.	PUNCT
admet-505	124	1	keywords	keyword	VERB
admet-505	124	2	drug	drug	NOUN
admet-505	124	3	-	-	PUNCT
admet-505	124	4	micelle	micelle	NOUN
admet-505	124	5	binding	bind	VERB
admet-505	124	6	constant	constant	ADJ
admet-505	124	7	;	;	PUNCT
admet-505	124	8	solubilization	solubilization	NOUN
admet-505	124	9	capacity	capacity	NOUN
admet-505	124	10	;	;	PUNCT
admet-505	124	11	supersaturation	supersaturation	NOUN
admet-505	124	12	;	;	PUNCT
admet-505	124	13	cocrystal	cocrystal	ADJ
admet-505	124	14	solubilization	solubilization	NOUN
admet-505	124	15	;	;	PUNCT
admet-505	124	16	solubility	solubility	NOUN
admet-505	124	17	-	-	PUNCT
admet-505	124	18	ph	ph	NOUN
admet-505	124	19	_	_	NOUN
admet-505	125	1	_	_	PUNCT
admet-505	126	1	_	_	PUNCT
admet-505	127	1	_	_	PUNCT
admet-505	128	1	_	_	PUNCT
admet-505	129	1	_	_	PUNCT
admet-505	130	1	_	_	PUNCT
admet-505	131	1	_	_	PUNCT
admet-505	132	1	_	_	PUNCT
admet-505	133	1	_	_	PUNCT
admet-505	134	1	_	_	PUNCT
admet-505	135	1	_	_	PUNCT
admet-505	136	1	_	_	PUNCT
admet-505	137	1	_	_	PUNCT
admet-505	138	1	_	_	PUNCT
admet-505	139	1	_	_	PUNCT
admet-505	140	1	_	_	PUNCT
admet-505	141	1	_	_	PUNCT
admet-505	142	1	_	_	PUNCT
admet-505	143	1	_	_	PUNCT
admet-505	144	1	_	_	PUNCT
admet-505	145	1	_	_	PUNCT
admet-505	146	1	_	_	PUNCT
admet-505	147	1	_	_	PUNCT
admet-505	148	1	_	_	PUNCT
admet-505	149	1	_	_	PUNCT
admet-505	150	1	_	_	PUNCT
admet-505	151	1	_	_	PUNCT
admet-505	152	1	_	_	PUNCT
admet-505	153	1	_	_	PUNCT
admet-505	154	1	_	_	PUNCT
admet-505	155	1	_	_	PUNCT
admet-505	156	1	_	_	PUNCT
admet-505	157	1	_	_	PUNCT
admet-505	158	1	_	_	PUNCT
admet-505	159	1	_	_	PUNCT
admet-505	160	1	_	_	PUNCT
admet-505	161	1	_	_	PUNCT
admet-505	162	1	_	_	PUNCT
admet-505	163	1	_	_	PUNCT
admet-505	164	1	_	_	PUNCT
admet-505	165	1	_	_	PUNCT
admet-505	166	1	_	_	PUNCT
admet-505	167	1	_	_	PUNCT
admet-505	168	1	_	_	PUNCT
admet-505	169	1	_	_	PUNCT
admet-505	170	1	_	_	PUNCT
admet-505	171	1	_	_	PUNCT
admet-505	172	1	_	_	PUNCT
admet-505	173	1	_	_	PUNCT
admet-505	174	1	_	_	PUNCT
admet-505	175	1	_	_	PUNCT
admet-505	176	1	_	_	PUNCT
admet-505	177	1	_	_	PUNCT
admet-505	178	1	_	_	PUNCT
admet-505	179	1	_	_	PUNCT
admet-505	180	1	_	_	PUNCT
admet-505	181	1	_	_	PUNCT
admet-505	182	1	_	_	PUNCT
admet-505	183	1	_	_	PUNCT
admet-505	184	1	_	_	PUNCT
admet-505	185	1	_	_	PUNCT
admet-505	186	1	_	_	PUNCT
admet-505	187	1	_	_	PUNCT
admet-505	188	1	_	_	PUNCT
admet-505	189	1	_	_	PUNCT
admet-505	190	1	_	_	PUNCT
admet-505	191	1	_	_	PUNCT
admet-505	192	1	_	_	PUNCT
admet-505	193	1	_	_	PUNCT
admet-505	194	1	_	_	PUNCT
admet-505	195	1	_	_	PUNCT
admet-505	196	1	_	_	PUNCT
admet-505	197	1	_	_	PUNCT
admet-505	198	1	_	_	PUNCT
admet-505	199	1	_	_	PUNCT
admet-505	200	1	_	_	PUNCT
admet-505	201	1	_	_	PUNCT
admet-505	202	1	_	_	PUNCT
admet-505	203	1	_	_	PUNCT
admet-505	204	1	_	_	PUNCT
admet-505	205	1	_	_	PUNCT
admet-505	206	1	_	_	PUNCT
admet-505	207	1	_	_	PUNCT
admet-505	208	1	_	_	PUNCT
admet-505	208	2	_	_	PUNCT
admet-505	209	1	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-505	209	2	mailto:alex@in-adme.com	mailto:alex@in-adme.com	PROPN
admet-505	209	3	alex	alex	PROPN
admet-505	209	4	avdeef	avdeef	PROPN
admet-505	209	5	admet	admet	PROPN
admet-505	209	6	&	&	CCONJ
admet-505	209	7	dmpk	dmpk	PROPN
admet-505	209	8	6(2	6(2	NUM
admet-505	209	9	)	)	PUNCT
admet-505	209	10	(	(	PUNCT
admet-505	209	11	2018	2018	NUM
admet-505	209	12	)	)	PUNCT
admet-505	209	13	105	105	NUM
admet-505	209	14	-	-	SYM
admet-505	209	15	139	139	NUM
admet-505	209	16	106	106	NUM
admet-505	209	17	introduction	introduction	NOUN
admet-505	209	18	this	this	DET
admet-505	209	19	review	review	NOUN
admet-505	209	20	focuses	focus	VERB
admet-505	209	21	on	on	ADP
admet-505	209	22	the	the	DET
admet-505	209	23	pharmaceutical	pharmaceutical	ADJ
admet-505	209	24	uses	use	NOUN
admet-505	209	25	of	of	ADP
admet-505	209	26	sodium	sodium	NOUN
admet-505	209	27	dodecyl	dodecyl	PROPN
admet-505	209	28	sulfate	sulfate	NOUN
admet-505	209	29	(	(	PUNCT
admet-505	209	30	sds	sds	NOUN
admet-505	209	31	;	;	PUNCT
admet-505	209	32	i.e.	i.e.	X
admet-505	209	33	,	,	PUNCT
admet-505	209	34	sodium	sodium	NOUN
admet-505	209	35	lauryl	lauryl	NOUN
admet-505	209	36	sulfate	sulfate	NOUN
admet-505	209	37	)	)	PUNCT
admet-505	209	38	to	to	PART
admet-505	209	39	solubilize	solubilize	VERB
admet-505	209	40	sparingly	sparingly	ADV
admet-505	209	41	-	-	PUNCT
admet-505	209	42	soluble	soluble	ADJ
admet-505	209	43	drugs	drug	NOUN
admet-505	209	44	by	by	ADP
admet-505	209	45	micellization	micellization	NOUN
admet-505	209	46	.	.	PUNCT
admet-505	210	1	the	the	DET
admet-505	210	2	mass	mass	ADJ
admet-505	210	3	action	action	NOUN
admet-505	210	4	framework	framework	NOUN
admet-505	210	5	is	be	AUX
admet-505	210	6	used	use	VERB
admet-505	210	7	to	to	PART
admet-505	210	8	describe	describe	VERB
admet-505	210	9	drug	drug	NOUN
admet-505	210	10	-	-	PUNCT
admet-505	210	11	surfactant	surfactant	NOUN
admet-505	210	12	equilibria	equilibrium	NOUN
admet-505	210	13	in	in	ADP
admet-505	210	14	drug	drug	NOUN
admet-505	210	15	-	-	PUNCT
admet-505	210	16	saturated	saturate	VERB
admet-505	210	17	suspensions	suspension	NOUN
admet-505	210	18	as	as	SCONJ
admet-505	210	19	a	a	DET
admet-505	210	20	function	function	NOUN
admet-505	210	21	of	of	ADP
admet-505	210	22	ph	ph	PROPN
admet-505	210	23	.	.	PROPN
admet-505	210	24	examples	example	NOUN
admet-505	210	25	applied	apply	VERB
admet-505	210	26	to	to	ADP
admet-505	210	27	solids	solid	NOUN
admet-505	210	28	in	in	ADP
admet-505	210	29	cocrystal	cocrystal	PROPN
admet-505	210	30	(	(	PUNCT
admet-505	210	31	cc	cc	NOUN
admet-505	210	32	)	)	PUNCT
admet-505	210	33	form	form	NOUN
admet-505	210	34	are	be	AUX
admet-505	210	35	considered	consider	VERB
admet-505	210	36	as	as	ADP
admet-505	210	37	part	part	NOUN
admet-505	210	38	of	of	ADP
admet-505	210	39	a	a	DET
admet-505	210	40	continuing	continue	VERB
admet-505	210	41	interest	interest	NOUN
admet-505	210	42	in	in	ADP
admet-505	210	43	developing	develop	VERB
admet-505	210	44	equilibrium	equilibrium	NOUN
admet-505	210	45	simulation	simulation	NOUN
admet-505	210	46	methods	method	NOUN
admet-505	210	47	to	to	PART
admet-505	210	48	identify	identify	VERB
admet-505	210	49	optimal	optimal	ADJ
admet-505	210	50	experimental	experimental	ADJ
admet-505	210	51	conditions	condition	NOUN
admet-505	210	52	for	for	ADP
admet-505	210	53	cocrystal	cocrystal	ADJ
admet-505	210	54	solubility	solubility	NOUN
admet-505	210	55	-	-	PUNCT
admet-505	210	56	ph	ph	ADJ
admet-505	210	57	measurements	measurement	NOUN
admet-505	210	58	.	.	PUNCT
admet-505	211	1	for	for	ADP
admet-505	211	2	orally	orally	ADV
admet-505	211	3	administered	administer	VERB
admet-505	211	4	drugs	drug	NOUN
admet-505	211	5	which	which	PRON
admet-505	211	6	are	be	AUX
admet-505	211	7	poorly	poorly	ADV
admet-505	211	8	soluble	soluble	ADJ
admet-505	211	9	in	in	ADP
admet-505	211	10	water	water	NOUN
admet-505	211	11	,	,	PUNCT
admet-505	211	12	a	a	DET
admet-505	211	13	number	number	NOUN
admet-505	211	14	of	of	ADP
admet-505	211	15	formulation	formulation	NOUN
admet-505	211	16	strategies	strategy	NOUN
admet-505	211	17	can	can	AUX
admet-505	211	18	be	be	AUX
admet-505	211	19	used	use	VERB
admet-505	211	20	to	to	PART
admet-505	211	21	improve	improve	VERB
admet-505	211	22	their	their	PRON
admet-505	211	23	rate	rate	NOUN
admet-505	211	24	and	and	CCONJ
admet-505	211	25	extent	extent	NOUN
admet-505	211	26	of	of	ADP
admet-505	211	27	absorption	absorption	NOUN
admet-505	211	28	[	[	X
admet-505	211	29	1	1	NUM
admet-505	211	30	]	]	PUNCT
admet-505	211	31	.	.	PUNCT
admet-505	212	1	for	for	ADP
admet-505	212	2	solid	solid	ADJ
admet-505	212	3	dosage	dosage	NOUN
admet-505	212	4	forms	form	NOUN
admet-505	212	5	,	,	PUNCT
admet-505	212	6	recent	recent	ADJ
admet-505	212	7	approaches	approach	NOUN
admet-505	212	8	have	have	AUX
admet-505	212	9	included	include	VERB
admet-505	212	10	the	the	DET
admet-505	212	11	use	use	NOUN
admet-505	212	12	of	of	ADP
admet-505	212	13	cc	cc	NOUN
admet-505	212	14	formulations	formulation	NOUN
admet-505	212	15	[	[	PUNCT
admet-505	212	16	2	2	NUM
admet-505	212	17	-	-	SYM
admet-505	212	18	5	5	NUM
admet-505	212	19	]	]	PUNCT
admet-505	212	20	.	.	PUNCT
admet-505	213	1	cocrystal	cocrystal	ADJ
admet-505	213	2	suspensions	suspension	NOUN
admet-505	213	3	can	can	AUX
admet-505	213	4	be	be	AUX
admet-505	213	5	stabilized	stabilize	VERB
admet-505	213	6	using	use	VERB
admet-505	213	7	surfactants	surfactant	NOUN
admet-505	213	8	[	[	X
admet-505	213	9	6	6	NUM
admet-505	213	10	-	-	SYM
admet-505	213	11	9	9	NUM
admet-505	213	12	]	]	PUNCT
admet-505	213	13	.	.	PUNCT
admet-505	214	1	for	for	ADP
admet-505	214	2	liquid	liquid	ADJ
admet-505	214	3	dosage	dosage	NOUN
admet-505	214	4	forms	form	NOUN
admet-505	214	5	(	(	PUNCT
admet-505	214	6	e.g.	e.g.	ADV
admet-505	214	7	,	,	PUNCT
admet-505	214	8	soft	soft	ADJ
admet-505	214	9	gel	gel	NOUN
admet-505	214	10	capsules	capsule	NOUN
admet-505	214	11	)	)	PUNCT
admet-505	214	12	,	,	PUNCT
admet-505	214	13	surfactants	surfactant	NOUN
admet-505	214	14	are	be	AUX
admet-505	214	15	used	use	VERB
admet-505	214	16	to	to	PART
admet-505	214	17	solubilize	solubilize	VERB
admet-505	214	18	the	the	DET
admet-505	214	19	active	active	ADJ
admet-505	214	20	pharmaceutical	pharmaceutical	ADJ
admet-505	214	21	ingredient	ingredient	NOUN
admet-505	214	22	(	(	PUNCT
admet-505	214	23	api	api	NOUN
admet-505	214	24	)	)	PUNCT
admet-505	215	1	[	[	X
admet-505	215	2	10	10	NUM
admet-505	215	3	-	-	SYM
admet-505	215	4	12	12	NUM
admet-505	215	5	]	]	PUNCT
admet-505	215	6	.	.	PUNCT
admet-505	216	1	in	in	ADP
admet-505	216	2	standard	standard	ADJ
admet-505	216	3	dissolution	dissolution	ADJ
admet-505	216	4	measurements	measurement	NOUN
admet-505	216	5	of	of	ADP
admet-505	216	6	poorly	poorly	ADV
admet-505	216	7	-	-	PUNCT
admet-505	216	8	soluble	soluble	ADJ
admet-505	216	9	solids	solid	NOUN
admet-505	216	10	,	,	PUNCT
admet-505	216	11	some	some	DET
admet-505	216	12	compounds	compound	NOUN
admet-505	216	13	initially	initially	ADV
admet-505	216	14	show	show	VERB
admet-505	216	15	an	an	DET
admet-505	216	16	enhanced	enhanced	ADJ
admet-505	216	17	release	release	NOUN
admet-505	216	18	of	of	ADP
admet-505	216	19	the	the	DET
admet-505	216	20	api	api	NOUN
admet-505	216	21	,	,	PUNCT
admet-505	216	22	forming	form	VERB
admet-505	216	23	a	a	DET
admet-505	216	24	supersaturated	supersaturated	ADJ
admet-505	216	25	solution	solution	NOUN
admet-505	216	26	,	,	PUNCT
admet-505	216	27	which	which	PRON
admet-505	216	28	after	after	ADP
admet-505	216	29	a	a	DET
admet-505	216	30	while	while	NOUN
admet-505	216	31	results	result	NOUN
admet-505	216	32	in	in	ADP
admet-505	216	33	the	the	DET
admet-505	216	34	precipitation	precipitation	NOUN
admet-505	216	35	of	of	ADP
admet-505	216	36	the	the	DET
admet-505	216	37	crystalline	crystalline	ADJ
admet-505	216	38	api	api	NOUN
admet-505	216	39	(	(	PUNCT
admet-505	216	40	“	"	PUNCT
admet-505	216	41	spring	spring	NOUN
admet-505	216	42	and	and	CCONJ
admet-505	216	43	parachute	parachute	NOUN
admet-505	216	44	”	"	PUNCT
admet-505	216	45	s&p	s&p	PROPN
admet-505	216	46	effect	effect	NOUN
admet-505	216	47	)	)	PUNCT
admet-505	216	48	.	.	PUNCT
admet-505	217	1	cocrystals	cocrystal	NOUN
admet-505	217	2	generally	generally	ADV
admet-505	217	3	show	show	VERB
admet-505	217	4	such	such	DET
admet-505	217	5	a	a	DET
admet-505	217	6	tendency	tendency	NOUN
admet-505	217	7	.	.	PUNCT
admet-505	218	1	a	a	DET
admet-505	218	2	cocrystal	cocrystal	NOUN
admet-505	218	3	is	be	AUX
admet-505	218	4	a	a	DET
admet-505	218	5	composite	composite	NOUN
admet-505	218	6	of	of	ADP
admet-505	218	7	an	an	DET
admet-505	218	8	uncharged	uncharged	ADJ
admet-505	218	9	api	api	NOUN
admet-505	218	10	and	and	CCONJ
admet-505	218	11	an	an	DET
admet-505	218	12	uncharged	uncharged	ADJ
admet-505	218	13	water	water	NOUN
admet-505	218	14	-	-	PUNCT
admet-505	218	15	soluble	soluble	ADJ
admet-505	218	16	“	"	PUNCT
admet-505	218	17	coformer	coformer	NOUN
admet-505	218	18	”	"	PUNCT
admet-505	218	19	molecule	molecule	NOUN
admet-505	218	20	(	(	PUNCT
admet-505	218	21	e.g.	e.g.	ADJ
admet-505	218	22	,	,	PUNCT
admet-505	218	23	saccharin	saccharin	NOUN
admet-505	218	24	,	,	PUNCT
admet-505	218	25	nicotinamide	nicotinamide	NOUN
admet-505	218	26	,	,	PUNCT
admet-505	218	27	4	4	NUM
admet-505	218	28	-	-	PUNCT
admet-505	218	29	aminobenzoic	aminobenzoic	ADJ
admet-505	218	30	acid	acid	NOUN
admet-505	218	31	,	,	PUNCT
admet-505	218	32	etc	etc	X
admet-505	218	33	.	.	X
admet-505	218	34	)	)	PUNCT
admet-505	218	35	.	.	PUNCT
admet-505	219	1	as	as	SCONJ
admet-505	219	2	the	the	DET
admet-505	219	3	api	api	NOUN
admet-505	219	4	in	in	ADP
admet-505	219	5	the	the	DET
admet-505	219	6	cc	cc	NOUN
admet-505	219	7	is	be	AUX
admet-505	219	8	released	release	VERB
admet-505	219	9	into	into	ADP
admet-505	219	10	an	an	DET
admet-505	219	11	aqueous	aqueous	ADJ
admet-505	219	12	medium	medium	NOUN
admet-505	219	13	,	,	PUNCT
admet-505	219	14	a	a	DET
admet-505	219	15	supersaturated	supersaturated	ADJ
admet-505	219	16	solution	solution	NOUN
admet-505	219	17	is	be	AUX
admet-505	219	18	expected	expect	VERB
admet-505	219	19	to	to	PART
admet-505	219	20	form	form	VERB
admet-505	219	21	,	,	PUNCT
admet-505	219	22	with	with	ADP
admet-505	219	23	the	the	DET
admet-505	219	24	maximum	maximum	ADJ
admet-505	219	25	theoretical	theoretical	ADJ
admet-505	219	26	drug	drug	NOUN
admet-505	219	27	concentration	concentration	NOUN
admet-505	219	28	called	call	VERB
admet-505	219	29	“	"	PUNCT
admet-505	219	30	cocrystal	cocrystal	ADJ
admet-505	219	31	solubility	solubility	NOUN
admet-505	219	32	,	,	PUNCT
admet-505	220	1	”	"	PUNCT
admet-505	220	2	scc	scc	NOUN
admet-505	221	1	[	[	X
admet-505	221	2	5	5	NUM
admet-505	221	3	-	-	SYM
admet-505	221	4	9	9	NUM
admet-505	221	5	,	,	PUNCT
admet-505	221	6	13	13	NUM
admet-505	221	7	,	,	PUNCT
admet-505	221	8	14	14	NUM
admet-505	221	9	]	]	PUNCT
admet-505	221	10	.	.	PUNCT
admet-505	222	1	if	if	SCONJ
admet-505	222	2	sustained	sustain	VERB
admet-505	222	3	for	for	ADP
admet-505	222	4	a	a	DET
admet-505	222	5	few	few	ADJ
admet-505	222	6	hours	hour	NOUN
admet-505	222	7	,	,	PUNCT
admet-505	222	8	this	this	DET
admet-505	222	9	enhanced	enhanced	ADJ
admet-505	222	10	concentration	concentration	NOUN
admet-505	222	11	of	of	ADP
admet-505	222	12	the	the	DET
admet-505	222	13	api	api	NOUN
admet-505	222	14	can	can	AUX
admet-505	222	15	lead	lead	VERB
admet-505	222	16	to	to	ADP
admet-505	222	17	increased	increase	VERB
admet-505	222	18	oral	oral	ADJ
admet-505	222	19	absorption	absorption	NOUN
admet-505	222	20	[	[	X
admet-505	222	21	15	15	NUM
admet-505	222	22	]	]	PUNCT
admet-505	222	23	.	.	PUNCT
admet-505	223	1	compared	compare	VERB
admet-505	223	2	to	to	ADP
admet-505	223	3	amorphous	amorphous	ADJ
admet-505	223	4	solids	solid	NOUN
admet-505	223	5	,	,	PUNCT
admet-505	223	6	which	which	PRON
admet-505	223	7	also	also	ADV
admet-505	223	8	form	form	VERB
admet-505	223	9	supersaturated	supersaturated	ADJ
admet-505	223	10	solutions	solution	NOUN
admet-505	223	11	,	,	PUNCT
admet-505	223	12	ccs	ccs	PROPN
admet-505	223	13	,	,	PUNCT
admet-505	223	14	being	be	AUX
admet-505	223	15	crystalline	crystalline	ADJ
admet-505	223	16	,	,	PUNCT
admet-505	223	17	are	be	AUX
admet-505	223	18	likely	likely	ADJ
admet-505	223	19	to	to	PART
admet-505	223	20	have	have	VERB
admet-505	223	21	better	well	ADJ
admet-505	223	22	long	long	ADJ
admet-505	223	23	-	-	PUNCT
admet-505	223	24	term	term	NOUN
admet-505	223	25	solid	solid	ADJ
admet-505	223	26	-	-	PUNCT
admet-505	223	27	state	state	NOUN
admet-505	223	28	thermal	thermal	ADJ
admet-505	223	29	,	,	PUNCT
admet-505	223	30	hygroscopic	hygroscopic	NOUN
admet-505	223	31	,	,	PUNCT
admet-505	223	32	and	and	CCONJ
admet-505	223	33	polymorphic	polymorphic	ADJ
admet-505	223	34	stability	stability	NOUN
admet-505	223	35	[	[	X
admet-505	223	36	1	1	NUM
admet-505	223	37	-	-	SYM
admet-505	223	38	3	3	NUM
admet-505	223	39	]	]	PUNCT
admet-505	223	40	.	.	PUNCT
admet-505	224	1	the	the	DET
admet-505	224	2	enhanced	enhanced	ADJ
admet-505	224	3	concentration	concentration	NOUN
admet-505	224	4	of	of	ADP
admet-505	224	5	the	the	DET
admet-505	224	6	api	api	NOUN
admet-505	224	7	in	in	ADP
admet-505	224	8	ccs	ccs	PROPN
admet-505	224	9	depends	depend	VERB
admet-505	224	10	on	on	ADP
admet-505	224	11	the	the	DET
admet-505	224	12	analytical	analytical	ADJ
admet-505	224	13	concentrations	concentration	NOUN
admet-505	224	14	of	of	ADP
admet-505	224	15	the	the	DET
admet-505	224	16	two	two	NUM
admet-505	224	17	underlying	underlie	VERB
admet-505	224	18	components	component	NOUN
admet-505	224	19	and	and	CCONJ
admet-505	224	20	on	on	ADP
admet-505	224	21	solution	solution	NOUN
admet-505	224	22	ph	ph	NOUN
admet-505	224	23	(	(	PUNCT
admet-505	224	24	in	in	ADP
admet-505	224	25	the	the	DET
admet-505	224	26	case	case	NOUN
admet-505	224	27	of	of	ADP
admet-505	224	28	ionizable	ionizable	ADJ
admet-505	224	29	components	component	NOUN
admet-505	224	30	)	)	PUNCT
admet-505	224	31	.	.	PUNCT
admet-505	225	1	enhancement	enhancement	NOUN
admet-505	225	2	is	be	AUX
admet-505	225	3	not	not	PART
admet-505	225	4	always	always	ADV
admet-505	225	5	sought	seek	VERB
admet-505	225	6	:	:	PUNCT
admet-505	225	7	some	some	DET
admet-505	225	8	cocrystals	cocrystal	NOUN
admet-505	225	9	(	(	PUNCT
admet-505	225	10	e.g.	e.g.	ADV
admet-505	225	11	,	,	PUNCT
admet-505	225	12	slow	slow	ADJ
admet-505	225	13	release	release	NOUN
admet-505	225	14	formulations	formulation	NOUN
admet-505	225	15	)	)	PUNCT
admet-505	225	16	are	be	AUX
admet-505	225	17	designed	design	VERB
admet-505	225	18	to	to	PART
admet-505	225	19	produce	produce	VERB
admet-505	225	20	a	a	DET
admet-505	225	21	supersaturated	supersaturated	ADJ
admet-505	225	22	solution	solution	NOUN
admet-505	225	23	with	with	ADP
admet-505	225	24	an	an	DET
admet-505	225	25	initially	initially	ADV
admet-505	225	26	decreased	decrease	VERB
admet-505	225	27	release	release	NOUN
admet-505	225	28	of	of	ADP
admet-505	225	29	a	a	DET
admet-505	225	30	water	water	NOUN
admet-505	225	31	-	-	PUNCT
admet-505	225	32	soluble	soluble	ADJ
admet-505	225	33	api	api	NOUN
admet-505	225	34	(	(	PUNCT
admet-505	225	35	“	"	PUNCT
admet-505	225	36	dive	dive	NOUN
admet-505	225	37	and	and	CCONJ
admet-505	225	38	surface	surface	NOUN
admet-505	225	39	”	"	PUNCT
admet-505	225	40	d&s	d&s	NOUN
admet-505	225	41	effect	effect	NOUN
admet-505	225	42	)	)	PUNCT
admet-505	226	1	[	[	X
admet-505	226	2	5,16,17	5,16,17	NUM
admet-505	226	3	]	]	PUNCT
admet-505	226	4	.	.	PUNCT
admet-505	227	1	however	however	ADV
admet-505	227	2	,	,	PUNCT
admet-505	227	3	the	the	DET
admet-505	227	4	supersaturated	supersaturated	ADJ
admet-505	227	5	state	state	NOUN
admet-505	227	6	is	be	AUX
admet-505	227	7	not	not	PART
admet-505	227	8	long	long	ADV
admet-505	227	9	-	-	PUNCT
admet-505	227	10	lasting	last	VERB
admet-505	227	11	for	for	ADP
admet-505	227	12	many	many	ADJ
admet-505	227	13	cc	cc	NOUN
admet-505	227	14	systems	system	NOUN
admet-505	227	15	studied	study	VERB
admet-505	227	16	in	in	ADP
admet-505	227	17	aqueous	aqueous	ADJ
admet-505	227	18	solution	solution	NOUN
admet-505	227	19	,	,	PUNCT
admet-505	227	20	given	give	VERB
admet-505	227	21	that	that	SCONJ
admet-505	227	22	the	the	DET
admet-505	227	23	api	api	NOUN
admet-505	227	24	(	(	PUNCT
admet-505	227	25	or	or	CCONJ
admet-505	227	26	coformer	coformer	NOUN
admet-505	227	27	,	,	PUNCT
admet-505	227	28	as	as	ADP
admet-505	227	29	in	in	ADP
admet-505	227	30	the	the	DET
admet-505	227	31	case	case	NOUN
admet-505	227	32	of	of	ADP
admet-505	227	33	d&s	d&s	PROPN
admet-505	227	34	)	)	PUNCT
admet-505	227	35	precipitates	precipitate	VERB
admet-505	227	36	to	to	ADP
admet-505	227	37	a	a	DET
admet-505	227	38	thermodynamically	thermodynamically	ADV
admet-505	227	39	stable	stable	ADJ
admet-505	227	40	form	form	NOUN
admet-505	227	41	,	,	PUNCT
admet-505	227	42	thus	thus	ADV
admet-505	227	43	lowering	lower	VERB
admet-505	227	44	(	(	PUNCT
admet-505	227	45	s&p	s&p	PROPN
admet-505	227	46	)	)	PUNCT
admet-505	227	47	or	or	CCONJ
admet-505	227	48	raising	raise	VERB
admet-505	227	49	(	(	PUNCT
admet-505	227	50	d&s	d&s	PROPN
admet-505	227	51	)	)	PUNCT
admet-505	227	52	the	the	DET
admet-505	227	53	concentration	concentration	NOUN
admet-505	227	54	of	of	ADP
admet-505	227	55	the	the	DET
admet-505	227	56	drug	drug	NOUN
admet-505	227	57	in	in	ADP
admet-505	227	58	solution	solution	NOUN
admet-505	227	59	.	.	PUNCT
admet-505	228	1	a	a	DET
admet-505	228	2	way	way	NOUN
admet-505	228	3	to	to	PART
admet-505	228	4	overcome	overcome	VERB
admet-505	228	5	this	this	DET
admet-505	228	6	api	api	NOUN
admet-505	228	7	/	/	SYM
admet-505	228	8	coformer	coformer	NOUN
admet-505	228	9	precipitation	precipitation	NOUN
admet-505	228	10	involves	involve	VERB
admet-505	228	11	the	the	DET
admet-505	228	12	use	use	NOUN
admet-505	228	13	of	of	ADP
admet-505	228	14	surfactants	surfactant	NOUN
admet-505	228	15	[	[	X
admet-505	228	16	6	6	NUM
admet-505	228	17	-	-	SYM
admet-505	228	18	9	9	NUM
admet-505	228	19	]	]	PUNCT
admet-505	228	20	.	.	PUNCT
admet-505	229	1	a	a	DET
admet-505	229	2	measure	measure	NOUN
admet-505	229	3	of	of	ADP
admet-505	229	4	the	the	DET
admet-505	229	5	ability	ability	NOUN
admet-505	229	6	of	of	ADP
admet-505	229	7	the	the	DET
admet-505	229	8	surfactant	surfactant	NOUN
admet-505	229	9	to	to	PART
admet-505	229	10	solubilize	solubilize	VERB
admet-505	229	11	a	a	DET
admet-505	229	12	drug	drug	NOUN
admet-505	229	13	is	be	AUX
admet-505	229	14	referred	refer	VERB
admet-505	229	15	to	to	ADP
admet-505	229	16	as	as	ADP
admet-505	229	17	solubilization	solubilization	NOUN
admet-505	229	18	capacity	capacity	NOUN
admet-505	229	19	,	,	PUNCT
admet-505	229	20	often	often	ADV
admet-505	229	21	denoted	denote	VERB
admet-505	229	22	by	by	ADP
admet-505	229	23	the	the	DET
admet-505	229	24	symbol	symbol	NOUN
admet-505	229	25	,	,	PUNCT
admet-505	229	26	k.	k.	PROPN
admet-505	230	1	it	it	PRON
admet-505	230	2	is	be	AUX
admet-505	230	3	defined	define	VERB
admet-505	230	4	as	as	ADP
admet-505	230	5	the	the	DET
admet-505	230	6	number	number	NOUN
admet-505	230	7	of	of	ADP
admet-505	230	8	moles	mole	NOUN
admet-505	230	9	of	of	ADP
admet-505	230	10	drug	drug	NOUN
admet-505	230	11	bound	bind	VERB
admet-505	230	12	to	to	ADP
admet-505	230	13	the	the	DET
admet-505	230	14	surfactant	surfactant	NOUN
admet-505	230	15	per	per	ADP
admet-505	230	16	mole	mole	NOUN
admet-505	230	17	of	of	ADP
admet-505	230	18	surfactant	surfactant	NOUN
admet-505	230	19	.	.	PUNCT
admet-505	231	1	as	as	ADP
admet-505	231	2	part	part	NOUN
admet-505	231	3	of	of	ADP
admet-505	231	4	this	this	DET
admet-505	231	5	study	study	NOUN
admet-505	231	6	,	,	PUNCT
admet-505	231	7	101	101	NUM
admet-505	231	8	published	publish	VERB
admet-505	231	9	sds	sds	PROPN
admet-505	231	10	k	k	PROPN
admet-505	231	11	values	value	NOUN
admet-505	231	12	of	of	ADP
admet-505	231	13	mostly	mostly	ADV
admet-505	231	14	poorly	poorly	ADV
admet-505	231	15	-	-	PUNCT
admet-505	231	16	soluble	soluble	ADJ
admet-505	231	17	drug	drug	NOUN
admet-505	231	18	molecules	molecule	NOUN
admet-505	231	19	were	be	AUX
admet-505	231	20	gathered	gather	VERB
admet-505	231	21	(	(	PUNCT
admet-505	231	22	table	table	NOUN
admet-505	231	23	1	1	NUM
admet-505	231	24	)	)	PUNCT
admet-505	231	25	.	.	PUNCT
admet-505	232	1	from	from	ADP
admet-505	232	2	these	these	PRON
admet-505	232	3	,	,	PUNCT
admet-505	232	4	a	a	DET
admet-505	232	5	simple	simple	ADJ
admet-505	232	6	k	k	PROPN
admet-505	232	7	prediction	prediction	NOUN
admet-505	232	8	model	model	NOUN
admet-505	232	9	was	be	AUX
admet-505	232	10	constructed	construct	VERB
admet-505	232	11	,	,	PUNCT
admet-505	232	12	as	as	ADP
admet-505	232	13	a	a	DET
admet-505	232	14	function	function	NOUN
admet-505	232	15	of	of	ADP
admet-505	232	16	the	the	DET
admet-505	232	17	api	api	NOUN
admet-505	232	18	intrinsic	intrinsic	ADJ
admet-505	232	19	solubility	solubility	NOUN
admet-505	232	20	and	and	CCONJ
admet-505	232	21	hydrogen	hydrogen	NOUN
admet-505	232	22	bond	bond	NOUN
admet-505	232	23	acceptor	acceptor	NOUN
admet-505	232	24	/	/	SYM
admet-505	232	25	donor	donor	NOUN
admet-505	232	26	potential	potential	NOUN
admet-505	232	27	.	.	PUNCT
admet-505	233	1	coupled	couple	VERB
admet-505	233	2	with	with	ADP
admet-505	233	3	the	the	DET
admet-505	233	4	in	in	ADP
admet-505	233	5	silico	silico	NOUN
admet-505	233	6	prediction	prediction	NOUN
admet-505	233	7	of	of	ADP
admet-505	233	8	the	the	DET
admet-505	233	9	k	k	PROPN
admet-505	233	10	values	value	NOUN
admet-505	233	11	,	,	PUNCT
admet-505	233	12	advantage	advantage	NOUN
admet-505	233	13	was	be	AUX
admet-505	233	14	taken	take	VERB
admet-505	233	15	of	of	ADP
admet-505	233	16	the	the	DET
admet-505	233	17	prediction	prediction	NOUN
admet-505	233	18	of	of	ADP
admet-505	233	19	the	the	DET
admet-505	233	20	solubility	solubility	NOUN
admet-505	233	21	product	product	NOUN
admet-505	233	22	,	,	PUNCT
admet-505	233	23	ksp	ksp	PROPN
admet-505	233	24	,	,	PUNCT
admet-505	233	25	of	of	ADP
admet-505	233	26	cocrystals	cocrystal	NOUN
admet-505	233	27	[	[	X
admet-505	233	28	17	17	NUM
admet-505	233	29	]	]	PUNCT
admet-505	233	30	,	,	PUNCT
admet-505	233	31	to	to	PART
admet-505	233	32	simulate	simulate	VERB
admet-505	233	33	aqueous	aqueous	ADJ
admet-505	233	34	solution	solution	NOUN
admet-505	233	35	speciation	speciation	NOUN
admet-505	233	36	as	as	ADP
admet-505	233	37	a	a	DET
admet-505	233	38	function	function	NOUN
admet-505	233	39	of	of	ADP
admet-505	233	40	ph	ph	NOUN
admet-505	233	41	,	,	PUNCT
admet-505	233	42	using	use	VERB
admet-505	233	43	a	a	DET
admet-505	233	44	recently	recently	ADV
admet-505	233	45	-	-	PUNCT
admet-505	233	46	described	describe	VERB
admet-505	233	47	computational	computational	ADJ
admet-505	233	48	approach	approach	NOUN
admet-505	233	49	[	[	X
admet-505	233	50	16	16	NUM
admet-505	233	51	]	]	PUNCT
admet-505	233	52	.	.	PUNCT
admet-505	234	1	these	these	DET
admet-505	234	2	simulation	simulation	NOUN
admet-505	234	3	calculations	calculation	NOUN
admet-505	234	4	can	can	AUX
admet-505	234	5	be	be	AUX
admet-505	234	6	used	use	VERB
admet-505	234	7	to	to	PART
admet-505	234	8	probe	probe	VERB
admet-505	234	9	conditions	condition	NOUN
admet-505	234	10	favorable	favorable	ADJ
admet-505	234	11	to	to	ADP
admet-505	234	12	the	the	DET
admet-505	234	13	design	design	NOUN
admet-505	234	14	of	of	ADP
admet-505	234	15	cocrystal	cocrystal	ADJ
admet-505	234	16	experiments	experiment	NOUN
admet-505	234	17	where	where	SCONJ
admet-505	234	18	sds	sds	PROPN
admet-505	234	19	is	be	AUX
admet-505	234	20	used	use	VERB
admet-505	234	21	to	to	PART
admet-505	234	22	stabilize	stabilize	VERB
admet-505	234	23	cc	cc	NOUN
admet-505	234	24	suspensions	suspension	NOUN
admet-505	234	25	against	against	ADP
admet-505	234	26	precipitation	precipitation	NOUN
admet-505	234	27	of	of	ADP
admet-505	234	28	the	the	DET
admet-505	234	29	api	api	NOUN
admet-505	234	30	.	.	PUNCT
admet-505	235	1	predictions	prediction	NOUN
admet-505	235	2	can	can	AUX
admet-505	235	3	be	be	AUX
admet-505	235	4	extended	extend	VERB
admet-505	235	5	to	to	ADP
admet-505	235	6	ccs	ccs	NOUN
admet-505	235	7	whose	whose	DET
admet-505	235	8	solution	solution	NOUN
admet-505	235	9	thermodynamics	thermodynamic	NOUN
admet-505	235	10	had	have	AUX
admet-505	235	11	not	not	PART
admet-505	235	12	been	be	AUX
admet-505	235	13	studied	study	VERB
admet-505	235	14	.	.	PUNCT
admet-505	236	1	even	even	ADV
admet-505	236	2	drugs	drug	NOUN
admet-505	236	3	not	not	PART
admet-505	236	4	known	know	VERB
admet-505	236	5	to	to	PART
admet-505	236	6	form	form	VERB
admet-505	236	7	ccs	ccs	PROPN
admet-505	236	8	can	can	AUX
admet-505	236	9	be	be	AUX
admet-505	236	10	tested	test	VERB
admet-505	236	11	against	against	ADP
admet-505	236	12	a	a	DET
admet-505	236	13	series	series	NOUN
admet-505	236	14	of	of	ADP
admet-505	236	15	coformer	coformer	NOUN
admet-505	236	16	candidates	candidate	NOUN
admet-505	236	17	.	.	PUNCT
admet-505	237	1	examples	example	NOUN
admet-505	237	2	are	be	AUX
admet-505	237	3	presented	present	VERB
admet-505	237	4	in	in	ADP
admet-505	237	5	the	the	DET
admet-505	237	6	study	study	NOUN
admet-505	237	7	to	to	PART
admet-505	237	8	illustrate	illustrate	VERB
admet-505	237	9	some	some	PRON
admet-505	237	10	of	of	ADP
admet-505	237	11	the	the	DET
admet-505	237	12	possible	possible	ADJ
admet-505	237	13	uses	use	NOUN
admet-505	237	14	of	of	ADP
admet-505	237	15	ksp	ksp	PROPN
admet-505	237	16	and	and	CCONJ
admet-505	237	17	k	k	PROPN
admet-505	237	18	values	value	NOUN
admet-505	237	19	.	.	PUNCT
admet-505	238	1	admet	admet	PROPN
admet-505	238	2	&	&	CCONJ
admet-505	238	3	dmpk	dmpk	PROPN
admet-505	238	4	6(2	6(2	NUM
admet-505	238	5	)	)	PUNCT
admet-505	238	6	(	(	PUNCT
admet-505	238	7	2018	2018	NUM
admet-505	238	8	)	)	PUNCT
admet-505	238	9	105	105	NUM
admet-505	238	10	-	-	SYM
admet-505	238	11	139	139	NUM
admet-505	238	12	cocrystal	cocrystal	ADJ
admet-505	238	13	solubility	solubility	NOUN
admet-505	238	14	-	-	PUNCT
admet-505	238	15	ph	ph	VERB
admet-505	238	16	,	,	PUNCT
admet-505	238	17	drug	drug	NOUN
admet-505	238	18	solubilization	solubilization	NOUN
admet-505	238	19	capacity	capacity	NOUN
admet-505	238	20	of	of	ADP
admet-505	238	21	sds	sds	PROPN
admet-505	238	22	,	,	PUNCT
admet-505	238	23	mass	mass	ADJ
admet-505	238	24	action	action	NOUN
admet-505	238	25	model	model	NOUN
admet-505	238	26	doi	doi	PROPN
admet-505	238	27	:	:	PUNCT
admet-505	238	28	10.5599	10.5599	NUM
admet-505	238	29	/	/	SYM
admet-505	238	30	admet.505	admet.505	PROPN
admet-505	238	31	107	107	NUM
admet-505	238	32	background	background	NOUN
admet-505	238	33	–	–	PUNCT
admet-505	238	34	drug	drug	NOUN
admet-505	238	35	solubilization	solubilization	NOUN
admet-505	238	36	by	by	ADP
admet-505	238	37	surfactants	surfactant	NOUN
admet-505	238	38	physicochemical	physicochemical	ADJ
admet-505	238	39	properties	property	NOUN
admet-505	238	40	of	of	ADP
admet-505	238	41	common	common	ADJ
admet-505	238	42	surfactants	surfactant	NOUN
admet-505	238	43	surfactants	surfactant	NOUN
admet-505	238	44	are	be	AUX
admet-505	238	45	surface	surface	NOUN
admet-505	238	46	-	-	PUNCT
admet-505	238	47	active	active	ADJ
admet-505	238	48	molecules	molecule	NOUN
admet-505	238	49	which	which	PRON
admet-505	238	50	contain	contain	VERB
admet-505	238	51	a	a	DET
admet-505	238	52	hydrophobic	hydrophobic	NOUN
admet-505	238	53	region	region	NOUN
admet-505	238	54	and	and	CCONJ
admet-505	238	55	a	a	DET
admet-505	238	56	hydrophilic	hydrophilic	ADJ
admet-505	238	57	head	head	NOUN
admet-505	238	58	group	group	NOUN
admet-505	238	59	.	.	PUNCT
admet-505	239	1	such	such	ADJ
admet-505	239	2	amphiphilic	amphiphilic	ADJ
admet-505	239	3	molecules	molecule	NOUN
admet-505	239	4	dissolve	dissolve	VERB
admet-505	239	5	in	in	ADP
admet-505	239	6	aqueous	aqueous	ADJ
admet-505	239	7	solution	solution	NOUN
admet-505	239	8	in	in	ADP
admet-505	239	9	ways	way	NOUN
admet-505	239	10	that	that	PRON
admet-505	239	11	minimize	minimize	VERB
admet-505	239	12	contact	contact	NOUN
admet-505	239	13	between	between	ADP
admet-505	239	14	water	water	NOUN
admet-505	239	15	and	and	CCONJ
admet-505	239	16	hydrophobic	hydrophobic	NOUN
admet-505	239	17	parts	part	NOUN
admet-505	239	18	of	of	ADP
admet-505	239	19	the	the	DET
admet-505	239	20	surfactant	surfactant	NOUN
admet-505	239	21	.	.	PUNCT
admet-505	240	1	this	this	PRON
admet-505	240	2	lowers	lower	VERB
admet-505	240	3	the	the	DET
admet-505	240	4	free	free	ADJ
admet-505	240	5	energy	energy	NOUN
admet-505	240	6	of	of	ADP
admet-505	240	7	solvation	solvation	NOUN
admet-505	240	8	.	.	PUNCT
admet-505	241	1	at	at	ADP
admet-505	241	2	low	low	ADJ
admet-505	241	3	concentrations	concentration	NOUN
admet-505	241	4	these	these	DET
admet-505	241	5	molecules	molecule	NOUN
admet-505	241	6	tend	tend	VERB
admet-505	241	7	to	to	PART
admet-505	241	8	accumulate	accumulate	VERB
admet-505	241	9	at	at	ADP
admet-505	241	10	the	the	DET
admet-505	241	11	boundaries	boundary	NOUN
admet-505	241	12	between	between	ADP
admet-505	241	13	two	two	NUM
admet-505	241	14	phases	phase	NOUN
admet-505	241	15	,	,	PUNCT
admet-505	241	16	such	such	ADJ
admet-505	241	17	as	as	ADP
admet-505	241	18	the	the	DET
admet-505	241	19	air	air	NOUN
admet-505	241	20	-	-	PUNCT
admet-505	241	21	water	water	NOUN
admet-505	241	22	interface	interface	NOUN
admet-505	241	23	,	,	PUNCT
admet-505	241	24	where	where	SCONJ
admet-505	241	25	the	the	DET
admet-505	241	26	hydrophobic	hydrophobic	NOUN
admet-505	241	27	groups	group	NOUN
admet-505	241	28	position	position	NOUN
admet-505	241	29	on	on	ADP
admet-505	241	30	the	the	DET
admet-505	241	31	airside	airside	NOUN
admet-505	241	32	.	.	PUNCT
admet-505	242	1	solid	solid	ADJ
admet-505	242	2	-	-	PUNCT
admet-505	242	3	liquid	liquid	ADJ
admet-505	242	4	interfaces	interface	NOUN
admet-505	242	5	may	may	AUX
admet-505	242	6	also	also	ADV
admet-505	242	7	be	be	AUX
admet-505	242	8	sites	site	NOUN
admet-505	242	9	of	of	ADP
admet-505	242	10	adsorption	adsorption	NOUN
admet-505	242	11	(	(	PUNCT
admet-505	242	12	e.g.	e.g.	ADV
admet-505	242	13	,	,	PUNCT
admet-505	242	14	vessel	vessel	NOUN
admet-505	242	15	walls	wall	NOUN
admet-505	242	16	,	,	PUNCT
admet-505	242	17	filter	filter	NOUN
admet-505	242	18	barriers	barrier	NOUN
admet-505	242	19	,	,	PUNCT
admet-505	242	20	undissolved	undissolve	VERB
admet-505	242	21	drug	drug	NOUN
admet-505	242	22	solids	solid	NOUN
admet-505	242	23	,	,	PUNCT
admet-505	242	24	etc	etc	X
admet-505	242	25	.	.	X
admet-505	242	26	)	)	PUNCT
admet-505	242	27	.	.	PUNCT
admet-505	243	1	such	such	ADJ
admet-505	243	2	available	available	ADJ
admet-505	243	3	interfacial	interfacial	ADJ
admet-505	243	4	sites	site	NOUN
admet-505	243	5	reach	reach	VERB
admet-505	243	6	saturation	saturation	NOUN
admet-505	243	7	as	as	ADP
admet-505	243	8	the	the	DET
admet-505	243	9	surfactant	surfactant	ADJ
admet-505	243	10	concentration	concentration	NOUN
admet-505	243	11	is	be	AUX
admet-505	243	12	increased	increase	VERB
admet-505	243	13	up	up	ADP
admet-505	243	14	to	to	ADP
admet-505	243	15	the	the	DET
admet-505	243	16	“	"	PUNCT
admet-505	243	17	critical	critical	ADJ
admet-505	243	18	micelle	micelle	NOUN
admet-505	243	19	concentration	concentration	NOUN
admet-505	243	20	”	"	PUNCT
admet-505	243	21	(	(	PUNCT
admet-505	243	22	cmc	cmc	PROPN
admet-505	243	23	)	)	PUNCT
admet-505	243	24	.	.	PUNCT
admet-505	244	1	above	above	ADP
admet-505	244	2	the	the	DET
admet-505	244	3	cmc	cmc	NOUN
admet-505	244	4	,	,	PUNCT
admet-505	244	5	unattached	unattached	ADJ
admet-505	244	6	surfactant	surfactant	ADJ
admet-505	244	7	monomers	monomer	NOUN
admet-505	244	8	begin	begin	VERB
admet-505	244	9	to	to	PART
admet-505	244	10	self	self	NOUN
admet-505	244	11	-	-	PUNCT
admet-505	244	12	associate	associate	NOUN
admet-505	244	13	to	to	PART
admet-505	244	14	form	form	VERB
admet-505	244	15	spheroidal	spheroidal	NOUN
admet-505	244	16	aggregates	aggregate	NOUN
admet-505	244	17	(	(	PUNCT
admet-505	244	18	“	"	PUNCT
admet-505	244	19	micelles	micelle	NOUN
admet-505	244	20	”	"	PUNCT
admet-505	244	21	)	)	PUNCT
admet-505	244	22	in	in	ADP
admet-505	244	23	the	the	DET
admet-505	244	24	bulk	bulk	ADJ
admet-505	244	25	aqueous	aqueous	ADJ
admet-505	244	26	solution	solution	NOUN
admet-505	244	27	,	,	PUNCT
admet-505	244	28	with	with	ADP
admet-505	244	29	hydrophobic	hydrophobic	NOUN
admet-505	244	30	portions	portion	NOUN
admet-505	244	31	of	of	ADP
admet-505	244	32	the	the	DET
admet-505	244	33	surfactant	surfactant	NOUN
admet-505	244	34	positioning	positioning	NOUN
admet-505	244	35	in	in	ADP
admet-505	244	36	the	the	DET
admet-505	244	37	core	core	NOUN
admet-505	244	38	of	of	ADP
admet-505	244	39	the	the	DET
admet-505	244	40	micelle	micelle	NOUN
admet-505	244	41	and	and	CCONJ
admet-505	244	42	hydrophilic	hydrophilic	ADJ
admet-505	244	43	parts	part	NOUN
admet-505	244	44	forming	form	VERB
admet-505	244	45	a	a	DET
admet-505	244	46	shell	shell	NOUN
admet-505	244	47	around	around	ADP
admet-505	244	48	the	the	DET
admet-505	244	49	micelle	micelle	NOUN
admet-505	244	50	body	body	NOUN
admet-505	244	51	.	.	PUNCT
admet-505	245	1	micelles	micelle	NOUN
admet-505	245	2	may	may	AUX
admet-505	245	3	consist	consist	VERB
admet-505	245	4	of	of	ADP
admet-505	245	5	50	50	NUM
admet-505	245	6	-	-	SYM
admet-505	245	7	100	100	NUM
admet-505	245	8	or	or	CCONJ
admet-505	245	9	more	more	ADJ
admet-505	245	10	surfactant	surfactant	ADJ
admet-505	245	11	molecules	molecule	NOUN
admet-505	245	12	.	.	PUNCT
admet-505	246	1	the	the	DET
admet-505	246	2	cmc	cmc	NOUN
admet-505	246	3	is	be	AUX
admet-505	246	4	detected	detect	VERB
admet-505	246	5	as	as	ADP
admet-505	246	6	the	the	DET
admet-505	246	7	point	point	NOUN
admet-505	246	8	corresponding	correspond	VERB
admet-505	246	9	to	to	ADP
admet-505	246	10	the	the	DET
admet-505	246	11	maximum	maximum	ADJ
admet-505	246	12	change	change	NOUN
admet-505	246	13	in	in	ADP
admet-505	246	14	the	the	DET
admet-505	246	15	gradient	gradient	NOUN
admet-505	246	16	of	of	ADP
admet-505	246	17	a	a	DET
admet-505	246	18	particular	particular	ADJ
admet-505	246	19	property	property	NOUN
admet-505	246	20	(	(	PUNCT
admet-505	246	21	e.g.	e.g.	ADV
admet-505	246	22	,	,	PUNCT
admet-505	246	23	surface	surface	NOUN
admet-505	246	24	tension	tension	NOUN
admet-505	246	25	,	,	PUNCT
admet-505	246	26	conductivity	conductivity	NOUN
admet-505	246	27	,	,	PUNCT
admet-505	246	28	osmotic	osmotic	ADJ
admet-505	246	29	pressure	pressure	NOUN
admet-505	246	30	,	,	PUNCT
admet-505	246	31	drug	drug	NOUN
admet-505	246	32	-	-	PUNCT
admet-505	246	33	micelle	micelle	NOUN
admet-505	246	34	binding	binding	ADJ
admet-505	246	35	,	,	PUNCT
admet-505	246	36	surfactant	surfactant	ADJ
admet-505	246	37	monomer	monomer	NOUN
admet-505	246	38	and	and	CCONJ
admet-505	246	39	counterion	counterion	NOUN
admet-505	246	40	concentrations	concentration	NOUN
admet-505	246	41	,	,	PUNCT
admet-505	246	42	etc	etc	X
admet-505	246	43	.	.	X
admet-505	246	44	)	)	PUNCT
admet-505	247	1	vs.	vs.	ADP
admet-505	247	2	total	total	ADJ
admet-505	247	3	surfactant	surfactant	ADJ
admet-505	247	4	concentration	concentration	NOUN
admet-505	247	5	.	.	PUNCT
admet-505	248	1	on	on	ADP
admet-505	248	2	further	further	ADJ
admet-505	248	3	increases	increase	NOUN
admet-505	248	4	in	in	ADP
admet-505	248	5	concentration	concentration	NOUN
admet-505	248	6	above	above	ADP
admet-505	248	7	the	the	DET
admet-505	248	8	cmc	cmc	NOUN
admet-505	248	9	,	,	PUNCT
admet-505	248	10	the	the	DET
admet-505	248	11	monomer	monomer	NOUN
admet-505	248	12	concentration	concentration	NOUN
admet-505	248	13	more	more	ADV
admet-505	248	14	or	or	CCONJ
admet-505	248	15	less	less	ADJ
admet-505	248	16	plateaus	plateaus	NOUN
admet-505	248	17	while	while	SCONJ
admet-505	248	18	the	the	DET
admet-505	248	19	micelle	micelle	NOUN
admet-505	248	20	aggregates	aggregate	NOUN
admet-505	248	21	continue	continue	VERB
admet-505	248	22	to	to	PART
admet-505	248	23	increase	increase	VERB
admet-505	248	24	in	in	ADP
admet-505	248	25	number	number	NOUN
admet-505	248	26	but	but	CCONJ
admet-505	248	27	generally	generally	ADV
admet-505	248	28	not	not	PART
admet-505	248	29	in	in	ADP
admet-505	248	30	size	size	NOUN
admet-505	248	31	.	.	PUNCT
admet-505	249	1	these	these	DET
admet-505	249	2	micelle	micelle	NOUN
admet-505	249	3	bodies	body	NOUN
admet-505	249	4	are	be	AUX
admet-505	249	5	capable	capable	ADJ
admet-505	249	6	of	of	ADP
admet-505	249	7	encapsulating	encapsulate	VERB
admet-505	249	8	drug	drug	NOUN
admet-505	249	9	molecules	molecule	NOUN
admet-505	249	10	.	.	PUNCT
admet-505	250	1	poorly	poorly	ADV
admet-505	250	2	-	-	PUNCT
admet-505	250	3	soluble	soluble	ADJ
admet-505	250	4	apolar	apolar	ADJ
admet-505	250	5	drugs	drug	NOUN
admet-505	250	6	are	be	AUX
admet-505	250	7	drawn	draw	VERB
admet-505	250	8	into	into	ADP
admet-505	250	9	the	the	DET
admet-505	250	10	core	core	NOUN
admet-505	250	11	of	of	ADP
admet-505	250	12	the	the	DET
admet-505	250	13	micelle	micelle	NOUN
admet-505	250	14	.	.	PUNCT
admet-505	251	1	charged	charge	VERB
admet-505	251	2	or	or	CCONJ
admet-505	251	3	polar	polar	ADJ
admet-505	251	4	amphiphilic	amphiphilic	ADJ
admet-505	251	5	drugs	drug	NOUN
admet-505	251	6	can	can	AUX
admet-505	251	7	position	position	VERB
admet-505	251	8	nearer	nearer	ADP
admet-505	251	9	the	the	DET
admet-505	251	10	water	water	NOUN
admet-505	251	11	-	-	PUNCT
admet-505	251	12	micelle	micelle	NOUN
admet-505	251	13	surface	surface	NOUN
admet-505	251	14	.	.	PUNCT
admet-505	252	1	sodium	sodium	NOUN
admet-505	252	2	dodecyl	dodecyl	PROPN
admet-505	252	3	sulfate	sulfate	PROPN
admet-505	252	4	(	(	PUNCT
admet-505	252	5	sds	sds	PROPN
admet-505	252	6	)	)	PUNCT
admet-505	252	7	sodium	sodium	NOUN
admet-505	252	8	dodecyl	dodecyl	PROPN
admet-505	252	9	sulfate	sulfate	NOUN
admet-505	252	10	(	(	PUNCT
admet-505	252	11	sds	sds	PROPN
admet-505	252	12	)	)	PUNCT
admet-505	252	13	is	be	AUX
admet-505	252	14	a	a	DET
admet-505	252	15	common	common	ADJ
admet-505	252	16	anionic	anionic	ADJ
admet-505	252	17	surfactant	surfactant	NOUN
admet-505	252	18	.	.	PUNCT
admet-505	253	1	it	it	PRON
admet-505	253	2	is	be	AUX
admet-505	253	3	an	an	DET
admet-505	253	4	ester	ester	NOUN
admet-505	253	5	of	of	ADP
admet-505	253	6	sulfuric	sulfuric	ADJ
admet-505	253	7	acid	acid	NOUN
admet-505	253	8	,	,	PUNCT
admet-505	253	9	comprising	comprise	VERB
admet-505	253	10	a	a	DET
admet-505	253	11	single	single	ADJ
admet-505	253	12	aliphatic	aliphatic	ADJ
admet-505	253	13	c12	c12	NOUN
admet-505	253	14	chain	chain	NOUN
admet-505	253	15	(	(	PUNCT
admet-505	253	16	structure	structure	NOUN
admet-505	253	17	in	in	ADP
admet-505	253	18	fig	fig	NOUN
admet-505	253	19	.	.	PUNCT
admet-505	254	1	1a	1a	NOUN
admet-505	254	2	)	)	PUNCT
admet-505	254	3	.	.	PUNCT
admet-505	255	1	since	since	SCONJ
admet-505	255	2	the	the	DET
admet-505	255	3	pka	pka	PROPN
admet-505	255	4	is	be	AUX
admet-505	255	5	near	near	ADP
admet-505	255	6	zero	zero	NUM
admet-505	255	7	,	,	PUNCT
admet-505	255	8	the	the	DET
admet-505	255	9	sds	sds	PROPN
admet-505	255	10	monomer	monomer	NOUN
admet-505	255	11	is	be	AUX
admet-505	255	12	practically	practically	ADV
admet-505	255	13	fully	fully	ADV
admet-505	255	14	ionized	ionized	ADJ
admet-505	255	15	in	in	ADP
admet-505	255	16	water	water	NOUN
admet-505	255	17	.	.	PUNCT
admet-505	256	1	the	the	DET
admet-505	256	2	surfactant	surfactant	NOUN
admet-505	256	3	is	be	AUX
admet-505	256	4	generally	generally	ADV
admet-505	256	5	introduced	introduce	VERB
admet-505	256	6	into	into	ADP
admet-505	256	7	the	the	DET
admet-505	256	8	aqueous	aqueous	ADJ
admet-505	256	9	solution	solution	NOUN
admet-505	256	10	as	as	ADP
admet-505	256	11	the	the	DET
admet-505	256	12	sodium	sodium	NOUN
admet-505	256	13	salt	salt	NOUN
admet-505	256	14	.	.	PUNCT
admet-505	257	1	many	many	ADJ
admet-505	257	2	of	of	ADP
admet-505	257	3	the	the	DET
admet-505	257	4	physicochemical	physicochemical	ADJ
admet-505	257	5	properties	property	NOUN
admet-505	257	6	of	of	ADP
admet-505	257	7	sds	sds	PROPN
admet-505	257	8	are	be	AUX
admet-505	257	9	well	well	ADV
admet-505	257	10	characterized	characterized	ADJ
admet-505	257	11	[	[	PUNCT
admet-505	257	12	11	11	NUM
admet-505	257	13	,	,	PUNCT
admet-505	257	14	12	12	NUM
admet-505	257	15	,	,	PUNCT
admet-505	257	16	18	18	NUM
admet-505	257	17	-	-	SYM
admet-505	257	18	20	20	NUM
admet-505	257	19	]	]	PUNCT
admet-505	257	20	.	.	PUNCT
admet-505	258	1	it	it	PRON
admet-505	258	2	is	be	AUX
admet-505	258	3	considered	consider	VERB
admet-505	258	4	to	to	PART
admet-505	258	5	be	be	AUX
admet-505	258	6	a	a	DET
admet-505	258	7	safe	safe	ADJ
admet-505	258	8	excipient	excipient	NOUN
admet-505	258	9	in	in	ADP
admet-505	258	10	tablet	tablet	NOUN
admet-505	258	11	or	or	CCONJ
admet-505	258	12	capsule	capsule	NOUN
admet-505	258	13	formulations	formulation	NOUN
admet-505	258	14	.	.	PUNCT
admet-505	259	1	in	in	ADP
admet-505	259	2	water	water	NOUN
admet-505	259	3	,	,	PUNCT
admet-505	259	4	sds	sds	PROPN
admet-505	259	5	forms	form	NOUN
admet-505	259	6	nearly	nearly	ADV
admet-505	259	7	monodispersed	monodisperse	VERB
admet-505	259	8	micelles	micelle	NOUN
admet-505	259	9	with	with	ADP
admet-505	259	10	the	the	DET
admet-505	259	11	approximate	approximate	ADJ
admet-505	259	12	aggregation	aggregation	NOUN
admet-505	259	13	number	number	NOUN
admet-505	259	14	,	,	PUNCT
admet-505	259	15	nagg	nagg	NOUN
admet-505	259	16	=	=	NOUN
admet-505	259	17	62	62	NUM
admet-505	259	18	.	.	PUNCT
admet-505	260	1	at	at	ADP
admet-505	260	2	25	25	NUM
admet-505	260	3	°	°	NOUN
admet-505	260	4	c	c	NOUN
admet-505	260	5	the	the	DET
admet-505	260	6	cmc	cmc	NOUN
admet-505	260	7	is	be	AUX
admet-505	260	8	8.3	8.3	NUM
admet-505	260	9	mm	mm	NOUN
admet-505	260	10	in	in	ADP
admet-505	260	11	water	water	NOUN
admet-505	260	12	(	(	PUNCT
admet-505	260	13	value	value	NOUN
admet-505	260	14	varies	vary	VERB
admet-505	260	15	somewhat	somewhat	ADV
admet-505	260	16	,	,	PUNCT
admet-505	260	17	depending	depend	VERB
admet-505	260	18	on	on	ADP
admet-505	260	19	the	the	DET
admet-505	260	20	determination	determination	NOUN
admet-505	260	21	method	method	NOUN
admet-505	260	22	[	[	X
admet-505	260	23	18	18	NUM
admet-505	260	24	,	,	PUNCT
admet-505	260	25	19	19	NUM
admet-505	260	26	]	]	NUM
admet-505	260	27	)	)	PUNCT
admet-505	260	28	.	.	PUNCT
admet-505	261	1	solubilization	solubilization	NOUN
admet-505	261	2	of	of	ADP
admet-505	261	3	drugs	drug	NOUN
admet-505	261	4	can	can	AUX
admet-505	261	5	alter	alter	VERB
admet-505	261	6	the	the	DET
admet-505	261	7	cmc	cmc	NOUN
admet-505	261	8	[	[	X
admet-505	261	9	12	12	NUM
admet-505	261	10	]	]	PUNCT
admet-505	261	11	.	.	PUNCT
admet-505	262	1	the	the	DET
admet-505	262	2	negative	negative	ADJ
admet-505	262	3	charge	charge	NOUN
admet-505	262	4	of	of	ADP
admet-505	262	5	the	the	DET
admet-505	262	6	62	62	NUM
admet-505	262	7	-	-	PUNCT
admet-505	262	8	sds	sds	NOUN
admet-505	262	9	micelle	micelle	NOUN
admet-505	262	10	is	be	AUX
admet-505	262	11	approximately	approximately	ADV
admet-505	262	12	80	80	NUM
admet-505	262	13	%	%	NOUN
admet-505	262	14	neutralized	neutralize	VERB
admet-505	262	15	by	by	ADP
admet-505	262	16	about	about	ADV
admet-505	262	17	50	50	NUM
admet-505	262	18	sodium	sodium	NOUN
admet-505	262	19	counterions	counterion	NOUN
admet-505	262	20	,	,	PUNCT
admet-505	262	21	electrostatically	electrostatically	ADV
admet-505	262	22	held	hold	VERB
admet-505	262	23	in	in	ADP
admet-505	262	24	the	the	DET
admet-505	262	25	stern	stern	ADJ
admet-505	262	26	layer	layer	NOUN
admet-505	262	27	comprising	comprise	VERB
admet-505	262	28	the	the	DET
admet-505	262	29	outer	outer	ADJ
admet-505	262	30	shell	shell	NOUN
admet-505	262	31	of	of	ADP
admet-505	262	32	the	the	DET
admet-505	262	33	spherical	spherical	ADJ
admet-505	262	34	micelle	micelle	NOUN
admet-505	262	35	[	[	X
admet-505	262	36	11	11	NUM
admet-505	262	37	]	]	PUNCT
admet-505	262	38	.	.	PUNCT
admet-505	263	1	above	above	ADP
admet-505	263	2	the	the	DET
admet-505	263	3	cmc	cmc	NOUN
admet-505	263	4	,	,	PUNCT
admet-505	263	5	the	the	DET
admet-505	263	6	solutions	solution	NOUN
admet-505	263	7	consist	consist	VERB
admet-505	263	8	of	of	ADP
admet-505	263	9	sdsmonomers	sdsmonomer	NOUN
admet-505	263	10	and	and	CCONJ
admet-505	263	11	mainly	mainly	ADV
admet-505	263	12	sds62na50	sds62na50	ADJ
admet-505	263	13	12aggregates	12aggregate	NOUN
admet-505	263	14	.	.	PUNCT
admet-505	264	1	effective	effective	ADJ
admet-505	264	2	charge	charge	NOUN
admet-505	264	3	on	on	ADP
admet-505	264	4	sds	sds	PROPN
admet-505	264	5	micelles	micelle	NOUN
admet-505	264	6	the	the	DET
admet-505	264	7	degree	degree	NOUN
admet-505	264	8	of	of	ADP
admet-505	264	9	counterion	counterion	NOUN
admet-505	264	10	dissociation	dissociation	NOUN
admet-505	264	11	in	in	ADP
admet-505	264	12	qm	qm	PROPN
admet-505	264	13	-	-	PUNCT
admet-505	264	14	charged	charge	VERB
admet-505	264	15	sds	sds	NOUN
admet-505	264	16	micelles	micelle	NOUN
admet-505	264	17	,	,	PUNCT
admet-505	264	18	α	α	NOUN
admet-505	264	19	=	=	SYM
admet-505	264	20	(	(	PUNCT
admet-505	264	21	nagg	nagg	PROPN
admet-505	264	22	qm)/nagg	qm)/nagg	PROPN
admet-505	264	23	,	,	PUNCT
admet-505	264	24	is	be	AUX
admet-505	264	25	(	(	PUNCT
admet-505	264	26	i	i	NOUN
admet-505	264	27	)	)	PUNCT
admet-505	264	28	not	not	PART
admet-505	264	29	expected	expect	VERB
admet-505	264	30	to	to	PART
admet-505	264	31	be	be	AUX
admet-505	264	32	greatly	greatly	ADV
admet-505	264	33	affected	affect	VERB
admet-505	264	34	by	by	ADP
admet-505	264	35	moderate	moderate	ADJ
admet-505	264	36	temperature	temperature	NOUN
admet-505	264	37	changes	change	NOUN
admet-505	264	38	,	,	PUNCT
admet-505	264	39	(	(	PUNCT
admet-505	264	40	ii	ii	NOUN
admet-505	264	41	)	)	PUNCT
admet-505	264	42	not	not	PART
admet-505	264	43	affected	affect	VERB
admet-505	264	44	by	by	ADP
admet-505	264	45	solubilization	solubilization	NOUN
admet-505	264	46	of	of	ADP
admet-505	264	47	small	small	ADJ
admet-505	264	48	organic	organic	ADJ
admet-505	264	49	solutes	solute	NOUN
admet-505	264	50	,	,	PUNCT
admet-505	264	51	(	(	PUNCT
admet-505	264	52	iii	iii	NOUN
admet-505	264	53	)	)	PUNCT
admet-505	264	54	only	only	ADV
admet-505	264	55	slightly	slightly	ADV
admet-505	264	56	dependent	dependent	ADJ
admet-505	264	57	on	on	ADP
admet-505	264	58	the	the	DET
admet-505	264	59	sds	sds	PROPN
admet-505	264	60	concentration	concentration	NOUN
admet-505	264	61	,	,	PUNCT
admet-505	264	62	and	and	CCONJ
admet-505	264	63	(	(	PUNCT
admet-505	264	64	iv	iv	X
admet-505	264	65	)	)	PUNCT
admet-505	264	66	strongly	strongly	ADV
admet-505	264	67	affected	affect	VERB
admet-505	264	68	by	by	ADP
admet-505	264	69	the	the	DET
admet-505	264	70	type	type	NOUN
admet-505	264	71	and	and	CCONJ
admet-505	264	72	concentration	concentration	NOUN
admet-505	264	73	of	of	ADP
admet-505	264	74	counterion	counterion	NOUN
admet-505	264	75	[	[	X
admet-505	264	76	12	12	NUM
admet-505	264	77	]	]	PUNCT
admet-505	264	78	.	.	PUNCT
admet-505	265	1	increasing	increase	VERB
admet-505	265	2	ionic	ionic	ADJ
admet-505	265	3	strength	strength	NOUN
admet-505	265	4	is	be	AUX
admet-505	265	5	expected	expect	VERB
admet-505	265	6	to	to	PART
admet-505	265	7	lower	lower	VERB
admet-505	265	8	α	α	NOUN
admet-505	265	9	(	(	PUNCT
admet-505	265	10	i.e.	i.e.	X
admet-505	265	11	,	,	PUNCT
admet-505	265	12	making	make	VERB
admet-505	265	13	the	the	DET
admet-505	265	14	micelles	micelle	NOUN
admet-505	265	15	less	less	ADV
admet-505	265	16	charged	charge	VERB
admet-505	265	17	)	)	PUNCT
admet-505	265	18	.	.	PUNCT
admet-505	266	1	in	in	ADP
admet-505	266	2	the	the	DET
admet-505	266	3	computations	computation	NOUN
admet-505	266	4	here	here	ADV
admet-505	266	5	,	,	PUNCT
admet-505	266	6	the	the	DET
admet-505	266	7	approximation	approximation	NOUN
admet-505	266	8	is	be	AUX
admet-505	266	9	made	make	VERB
admet-505	266	10	that	that	SCONJ
admet-505	266	11	α	α	PROPN
admet-505	266	12	and	and	CCONJ
admet-505	266	13	nagg	nagg	NOUN
admet-505	266	14	are	be	AUX
admet-505	266	15	constants	constant	NOUN
admet-505	266	16	(	(	PUNCT
admet-505	266	17	i.e.	i.e.	X
admet-505	266	18	,	,	PUNCT
admet-505	266	19	micelles	micelle	NOUN
admet-505	266	20	are	be	AUX
admet-505	266	21	assumed	assume	VERB
admet-505	266	22	to	to	PART
admet-505	266	23	be	be	AUX
admet-505	266	24	sds62na50	sds62na50	ADJ
admet-505	266	25	12-	12-	NUM
admet-505	266	26	)	)	PUNCT
admet-505	266	27	.	.	PUNCT
admet-505	267	1	mass	mass	PROPN
admet-505	267	2	action	action	NOUN
admet-505	267	3	equilibrium	equilibrium	NOUN
admet-505	267	4	model	model	NOUN
admet-505	267	5	for	for	ADP
admet-505	267	6	sodium	sodium	NOUN
admet-505	267	7	dodecyl	dodecyl	PROPN
admet-505	267	8	sulfate	sulfate	NOUN
admet-505	267	9	(	(	PUNCT
admet-505	267	10	sds	sds	PROPN
admet-505	267	11	)	)	PUNCT
admet-505	267	12	in	in	ADP
admet-505	267	13	the	the	DET
admet-505	267	14	mass	mass	ADJ
admet-505	267	15	action	action	NOUN
admet-505	267	16	treatment	treatment	NOUN
admet-505	267	17	of	of	ADP
admet-505	267	18	the	the	DET
admet-505	267	19	micelle	micelle	NOUN
admet-505	267	20	formation	formation	NOUN
admet-505	267	21	,	,	PUNCT
admet-505	267	22	sodium	sodium	NOUN
admet-505	267	23	ions	ion	NOUN
admet-505	267	24	,	,	PUNCT
admet-505	267	25	monomers	monomer	NOUN
admet-505	267	26	,	,	PUNCT
admet-505	267	27	and	and	CCONJ
admet-505	267	28	micelles	micelle	NOUN
admet-505	267	29	are	be	AUX
admet-505	267	30	in	in	ADP
admet-505	267	31	equilibrium	equilibrium	NOUN
admet-505	267	32	,	,	PUNCT
admet-505	267	33	according	accord	VERB
admet-505	267	34	to	to	ADP
admet-505	267	35	the	the	DET
admet-505	267	36	cumulative	cumulative	ADJ
admet-505	267	37	expression	expression	NOUN
admet-505	267	38	below	below	ADV
admet-505	267	39	(	(	PUNCT
admet-505	267	40	assuming	assume	VERB
admet-505	267	41	the	the	DET
admet-505	267	42	above	above	ADJ
admet-505	267	43	metrics	metric	NOUN
admet-505	267	44	)	)	PUNCT
admet-505	267	45	.	.	PUNCT
admet-505	268	1	alex	alex	PROPN
admet-505	268	2	avdeef	avdeef	PROPN
admet-505	268	3	admet	admet	PROPN
admet-505	268	4	&	&	CCONJ
admet-505	268	5	dmpk	dmpk	PROPN
admet-505	268	6	6(2	6(2	NUM
admet-505	268	7	)	)	PUNCT
admet-505	268	8	(	(	PUNCT
admet-505	268	9	2018	2018	NUM
admet-505	268	10	)	)	PUNCT
admet-505	268	11	105	105	NUM
admet-505	268	12	-	-	SYM
admet-505	268	13	139	139	NUM
admet-505	268	14	108	108	NUM
admet-505	268	15	62	62	NUM
admet-505	268	16	sds	sds	NOUN
admet-505	268	17	+	+	CCONJ
admet-505	268	18	50	50	NUM
admet-505	268	19	na	na	NOUN
admet-505	268	20	+	+	CCONJ
admet-505	268	21			X
admet-505	268	22	sds62na50	sds62na50	ADJ
admet-505	268	23	12	12	NUM
admet-505	268	24	ksds	ksds	NOUN
admet-505	268	25	=	=	PUNCT
admet-505	269	1	[	[	X
admet-505	269	2	sds62na50	sds62na50	ADJ
admet-505	269	3	12	12	NUM
admet-505	269	4	]	]	PUNCT
admet-505	269	5	/	/	PUNCT
admet-505	270	1	[	[	X
admet-505	270	2	sds	sds	X
admet-505	270	3	]	]	PUNCT
admet-505	270	4	62	62	NUM
admet-505	270	5	[	[	X
admet-505	270	6	na	na	X
admet-505	270	7	+	+	SYM
admet-505	270	8	]	]	PUNCT
admet-505	270	9	50	50	NUM
admet-505	270	10	(	(	PUNCT
admet-505	270	11	1	1	NUM
admet-505	270	12	)	)	PUNCT
admet-505	270	13	figure	figure	NOUN
admet-505	270	14	1	1	NUM
admet-505	270	15	shows	show	VERB
admet-505	270	16	the	the	DET
admet-505	270	17	simulation	simulation	NOUN
admet-505	270	18	results	result	NOUN
admet-505	270	19	based	base	VERB
admet-505	270	20	on	on	ADP
admet-505	270	21	eq	eq	ADP
admet-505	270	22	.	.	PUNCT
admet-505	271	1	(	(	PUNCT
admet-505	271	2	1	1	NUM
admet-505	271	3	)	)	PUNCT
admet-505	271	4	,	,	PUNCT
admet-505	271	5	where	where	SCONJ
admet-505	271	6	the	the	DET
admet-505	271	7	species	specie	NOUN
admet-505	271	8	in	in	ADP
admet-505	271	9	solution	solution	NOUN
admet-505	271	10	were	be	AUX
admet-505	271	11	calculated	calculate	VERB
admet-505	271	12	,	,	PUNCT
admet-505	271	13	as	as	ADP
admet-505	271	14	a	a	DET
admet-505	271	15	function	function	NOUN
admet-505	271	16	of	of	ADP
admet-505	271	17	added	add	VERB
admet-505	271	18	total	total	ADJ
admet-505	271	19	surfactant	surfactant	ADJ
admet-505	271	20	concentration	concentration	NOUN
admet-505	271	21	,	,	PUNCT
admet-505	271	22	using	use	VERB
admet-505	271	23	the	the	DET
admet-505	271	24	program	program	NOUN
admet-505	271	25	pdisol	pdisol	NOUN
admet-505	271	26	-	-	PUNCT
admet-505	271	27	x	x	SYM
admet-505	271	28	(	(	PUNCT
admet-505	271	29	cf	cf	NOUN
admet-505	271	30	.	.	NOUN
admet-505	271	31	,	,	PUNCT
admet-505	271	32	below	below	ADV
admet-505	271	33	)	)	PUNCT
admet-505	271	34	.	.	PUNCT
admet-505	272	1	figure	figure	NOUN
admet-505	272	2	1	1	NUM
admet-505	272	3	.	.	PUNCT
admet-505	273	1	simulation	simulation	NOUN
admet-505	273	2	of	of	ADP
admet-505	273	3	formation	formation	NOUN
admet-505	273	4	of	of	ADP
admet-505	273	5	sds	sds	PROPN
admet-505	273	6	micelles	micelle	NOUN
admet-505	273	7	.	.	PUNCT
admet-505	274	1	sodium	sodium	NOUN
admet-505	274	2	dodecyl	dodecyl	PROPN
admet-505	274	3	sulfate	sulfate	NOUN
admet-505	274	4	added	add	VERB
admet-505	274	5	to	to	ADP
admet-505	274	6	(	(	PUNCT
admet-505	274	7	a	a	DET
admet-505	274	8	)	)	PUNCT
admet-505	274	9	distilled	distil	VERB
admet-505	274	10	water	water	NOUN
admet-505	274	11	,	,	PUNCT
admet-505	274	12	(	(	PUNCT
admet-505	274	13	b	b	X
admet-505	274	14	)	)	PUNCT
admet-505	274	15	0.15	0.15	NUM
admet-505	274	16	m	m	NOUN
admet-505	274	17	nacl	nacl	ADJ
admet-505	274	18	solution	solution	NOUN
admet-505	274	19	,	,	PUNCT
admet-505	274	20	and	and	CCONJ
admet-505	274	21	(	(	PUNCT
admet-505	274	22	c	c	NOUN
admet-505	274	23	)	)	PUNCT
admet-505	274	24	ph	ph	ADJ
admet-505	274	25	7	7	NUM
admet-505	274	26	solution	solution	NOUN
admet-505	274	27	of	of	ADP
admet-505	274	28	50	50	NUM
admet-505	274	29	mm	mm	NOUN
admet-505	274	30	phosphate	phosphate	NOUN
admet-505	274	31	.	.	PUNCT
admet-505	275	1	ionic	ionic	ADJ
admet-505	275	2	strength	strength	NOUN
admet-505	275	3	and	and	CCONJ
admet-505	275	4	ph	ph	ADJ
admet-505	275	5	change	change	NOUN
admet-505	275	6	as	as	ADP
admet-505	275	7	concentration	concentration	NOUN
admet-505	275	8	of	of	ADP
admet-505	275	9	surfactant	surfactant	NOUN
admet-505	275	10	is	be	AUX
admet-505	275	11	increased	increase	VERB
admet-505	275	12	(	(	PUNCT
admet-505	275	13	d	d	NOUN
admet-505	275	14	)	)	PUNCT
admet-505	275	15	.	.	PUNCT
admet-505	276	1	see	see	VERB
admet-505	276	2	text	text	NOUN
admet-505	276	3	.	.	PUNCT
admet-505	277	1	in	in	ADP
admet-505	277	2	frame	frame	NOUN
admet-505	277	3	(	(	PUNCT
admet-505	277	4	a	a	X
admet-505	277	5	)	)	PUNCT
admet-505	277	6	,	,	PUNCT
admet-505	277	7	simulation	simulation	NOUN
admet-505	277	8	with	with	ADP
admet-505	277	9	aggregation	aggregation	NOUN
admet-505	277	10	constant	constant	ADJ
admet-505	277	11	log	log	NOUN
admet-505	277	12	ksds	ksds	NOUN
admet-505	277	13	=	=	NOUN
admet-505	277	14	230.6	230.6	NUM
admet-505	277	15	results	result	NOUN
admet-505	277	16	in	in	ADP
admet-505	277	17	cmc	cmc	NOUN
admet-505	277	18	=	=	PUNCT
admet-505	277	19	8.30	8.30	NUM
admet-505	277	20	mm	mm	NOUN
admet-505	277	21	.	.	PUNCT
admet-505	278	1	the	the	DET
admet-505	278	2	ksds	ksds	NOUN
admet-505	278	3	constant	constant	ADJ
admet-505	278	4	was	be	AUX
admet-505	278	5	systematically	systematically	ADV
admet-505	278	6	varied	varied	ADJ
admet-505	278	7	in	in	ADP
admet-505	278	8	the	the	DET
admet-505	278	9	calculations	calculation	NOUN
admet-505	278	10	until	until	SCONJ
admet-505	278	11	the	the	DET
admet-505	278	12	target	target	NOUN
admet-505	278	13	cmc	cmc	NOUN
admet-505	278	14	was	be	AUX
admet-505	278	15	obtained	obtain	VERB
admet-505	278	16	.	.	PUNCT
admet-505	279	1	as	as	SCONJ
admet-505	279	2	the	the	DET
admet-505	279	3	surfactant	surfactant	ADJ
admet-505	279	4	concentration	concentration	NOUN
admet-505	279	5	is	be	AUX
admet-505	279	6	increased	increase	VERB
admet-505	279	7	in	in	ADP
admet-505	279	8	the	the	DET
admet-505	279	9	simulation	simulation	NOUN
admet-505	279	10	,	,	PUNCT
admet-505	279	11	sdsand	sdsand	PROPN
admet-505	279	12	na+	na+	NOUN
admet-505	279	13	ions	ion	NOUN
admet-505	279	14	are	be	AUX
admet-505	279	15	released	release	VERB
admet-505	279	16	in	in	ADP
admet-505	279	17	equal	equal	ADJ
admet-505	279	18	concentrations	concentration	NOUN
admet-505	279	19	,	,	PUNCT
admet-505	279	20	until	until	SCONJ
admet-505	279	21	the	the	DET
admet-505	279	22	cmc	cmc	NOUN
admet-505	279	23	value	value	NOUN
admet-505	279	24	is	be	AUX
admet-505	279	25	reached	reach	VERB
admet-505	279	26	.	.	PUNCT
admet-505	280	1	with	with	ADP
admet-505	280	2	further	further	ADJ
admet-505	280	3	increases	increase	NOUN
admet-505	280	4	in	in	ADP
admet-505	280	5	surfactant	surfactant	ADJ
admet-505	280	6	concentration	concentration	NOUN
admet-505	280	7	,	,	PUNCT
admet-505	280	8	the	the	DET
admet-505	280	9	[	[	X
admet-505	280	10	sds-	sds-	X
admet-505	280	11	]	]	PUNCT
admet-505	280	12	and	and	CCONJ
admet-505	280	13	[	[	X
admet-505	280	14	na+	na+	X
admet-505	280	15	]	]	X
admet-505	280	16	concentrations	concentration	NOUN
admet-505	280	17	become	become	VERB
admet-505	280	18	unequal	unequal	ADJ
admet-505	280	19	:	:	PUNCT
admet-505	280	20	that	that	SCONJ
admet-505	280	21	of	of	ADP
admet-505	280	22	the	the	DET
admet-505	280	23	monomer	monomer	NOUN
admet-505	280	24	decreases	decrease	VERB
admet-505	280	25	,	,	PUNCT
admet-505	280	26	as	as	ADP
admet-505	280	27	that	that	PRON
admet-505	280	28	of	of	ADP
admet-505	280	29	the	the	DET
admet-505	280	30	counterion	counterion	NOUN
admet-505	280	31	increases	increase	NOUN
admet-505	280	32	,	,	PUNCT
admet-505	280	33	due	due	ADP
admet-505	280	34	to	to	ADP
admet-505	280	35	the	the	DET
admet-505	280	36	62:50	62:50	NUM
admet-505	280	37	stoichiometry	stoichiometry	NOUN
admet-505	280	38	of	of	ADP
admet-505	280	39	the	the	DET
admet-505	280	40	micelles	micelle	NOUN
admet-505	280	41	formed	form	VERB
admet-505	280	42	.	.	PUNCT
admet-505	281	1	the	the	DET
admet-505	281	2	ionic	ionic	ADJ
admet-505	281	3	strength	strength	NOUN
admet-505	281	4	changes	change	VERB
admet-505	281	5	over	over	ADP
admet-505	281	6	a	a	DET
admet-505	281	7	broad	broad	ADJ
admet-505	281	8	range	range	NOUN
admet-505	281	9	,	,	PUNCT
admet-505	281	10	increasing	increase	VERB
admet-505	281	11	from	from	ADP
admet-505	281	12	1	1	NUM
admet-505	281	13	to	to	PART
admet-505	281	14	130	130	NUM
admet-505	281	15	mm	mm	NOUN
admet-505	281	16	as	as	ADP
admet-505	281	17	the	the	DET
admet-505	281	18	surfactant	surfactant	ADJ
admet-505	281	19	concentration	concentration	NOUN
admet-505	281	20	is	be	AUX
admet-505	281	21	taken	take	VERB
admet-505	281	22	from	from	ADP
admet-505	281	23	1	1	NUM
admet-505	281	24	to	to	ADP
admet-505	281	25	104	104	NUM
admet-505	281	26	mm	mm	NOUN
admet-505	281	27	,	,	PUNCT
admet-505	281	28	which	which	PRON
admet-505	281	29	has	have	VERB
admet-505	281	30	an	an	DET
admet-505	281	31	impact	impact	NOUN
admet-505	281	32	on	on	ADP
admet-505	281	33	the	the	DET
admet-505	281	34	ksds	ksds	NOUN
admet-505	281	35	binding	bind	VERB
admet-505	281	36	constant	constant	ADJ
admet-505	281	37	and	and	CCONJ
admet-505	281	38	the	the	DET
admet-505	281	39	ph	ph	NOUN
admet-505	281	40	of	of	ADP
admet-505	281	41	the	the	DET
admet-505	281	42	solution	solution	NOUN
admet-505	281	43	(	(	PUNCT
admet-505	281	44	since	since	SCONJ
admet-505	281	45	electrode	electrode	NOUN
admet-505	281	46	calibration	calibration	NOUN
admet-505	281	47	parameters	parameter	NOUN
admet-505	281	48	depend	depend	VERB
admet-505	281	49	on	on	ADP
admet-505	281	50	ionic	ionic	ADJ
admet-505	281	51	strength	strength	NOUN
admet-505	281	52	;	;	PUNCT
admet-505	281	53	cf	cf	NOUN
admet-505	281	54	.	.	NOUN
admet-505	281	55	,	,	PUNCT
admet-505	281	56	fig	fig	NOUN
admet-505	281	57	.	.	PUNCT
admet-505	282	1	1d	1d	NUM
admet-505	282	2	)	)	PUNCT
admet-505	282	3	.	.	PUNCT
admet-505	283	1	in	in	ADP
admet-505	283	2	frame	frame	NOUN
admet-505	283	3	(	(	PUNCT
admet-505	283	4	b	b	NOUN
admet-505	283	5	)	)	PUNCT
admet-505	283	6	,	,	PUNCT
admet-505	283	7	the	the	DET
admet-505	283	8	surfactant	surfactant	NOUN
admet-505	283	9	is	be	AUX
admet-505	283	10	added	add	VERB
admet-505	283	11	to	to	ADP
admet-505	283	12	a	a	DET
admet-505	283	13	0.15	0.15	NUM
admet-505	283	14	m	m	NOUN
admet-505	283	15	nacl	nacl	ADJ
admet-505	283	16	solution	solution	NOUN
admet-505	283	17	.	.	PUNCT
admet-505	284	1	using	use	VERB
admet-505	284	2	the	the	DET
admet-505	284	3	same	same	ADJ
admet-505	284	4	ksds	ksds	NOUN
admet-505	284	5	constant	constant	ADJ
admet-505	284	6	,	,	PUNCT
admet-505	284	7	the	the	DET
admet-505	284	8	cmc	cmc	NOUN
admet-505	284	9	is	be	AUX
admet-505	284	10	predicted	predict	VERB
admet-505	284	11	to	to	PART
admet-505	284	12	decrease	decrease	VERB
admet-505	284	13	from	from	ADP
admet-505	284	14	8.30	8.30	NUM
admet-505	284	15	to	to	ADP
admet-505	284	16	1.01	1.01	NUM
admet-505	284	17	mm	mm	NOUN
admet-505	284	18	.	.	PUNCT
admet-505	285	1	the	the	DET
admet-505	285	2	ionic	ionic	ADJ
admet-505	285	3	strength	strength	NOUN
admet-505	285	4	increases	increase	VERB
admet-505	285	5	over	over	ADP
admet-505	285	6	a	a	DET
admet-505	285	7	narrow	narrow	ADJ
admet-505	285	8	range	range	NOUN
admet-505	285	9	,	,	PUNCT
admet-505	285	10	151	151	NUM
admet-505	285	11	-	-	SYM
admet-505	285	12	225	225	NUM
admet-505	285	13	mm	mm	NOUN
admet-505	285	14	,	,	PUNCT
admet-505	285	15	as	as	SCONJ
admet-505	285	16	the	the	DET
admet-505	285	17	surfactant	surfactant	NOUN
admet-505	285	18	increases	increase	VERB
admet-505	285	19	in	in	ADP
admet-505	285	20	concentration	concentration	NOUN
admet-505	285	21	from	from	ADP
admet-505	285	22	1	1	NUM
admet-505	285	23	to	to	PART
admet-505	285	24	60	60	NUM
admet-505	285	25	mm	mm	NOUN
admet-505	285	26	.	.	PUNCT
admet-505	286	1	in	in	ADP
admet-505	286	2	the	the	DET
admet-505	286	3	background	background	NOUN
admet-505	286	4	of	of	ADP
admet-505	286	5	higher	high	ADJ
admet-505	286	6	ionic	ionic	ADJ
admet-505	286	7	strength	strength	NOUN
admet-505	286	8	,	,	PUNCT
admet-505	286	9	the	the	DET
admet-505	286	10	[	[	X
admet-505	286	11	sds	sds	X
admet-505	286	12	]	]	X
admet-505	286	13	concentration	concentration	NOUN
admet-505	286	14	remains	remain	VERB
admet-505	286	15	relatively	relatively	ADV
admet-505	286	16	constant	constant	ADJ
admet-505	286	17	at	at	ADP
admet-505	286	18	1.01	1.01	NUM
admet-505	286	19	mm	mm	NOUN
admet-505	286	20	(	(	PUNCT
admet-505	286	21	the	the	DET
admet-505	286	22	cmc	cmc	NOUN
admet-505	286	23	value	value	NOUN
admet-505	286	24	)	)	PUNCT
admet-505	286	25	,	,	PUNCT
admet-505	286	26	as	as	SCONJ
admet-505	286	27	the	the	DET
admet-505	286	28	admet	admet	PROPN
admet-505	286	29	&	&	CCONJ
admet-505	286	30	dmpk	dmpk	PROPN
admet-505	286	31	6(2	6(2	NUM
admet-505	286	32	)	)	PUNCT
admet-505	286	33	(	(	PUNCT
admet-505	286	34	2018	2018	NUM
admet-505	286	35	)	)	PUNCT
admet-505	286	36	105	105	NUM
admet-505	286	37	-	-	SYM
admet-505	286	38	139	139	NUM
admet-505	286	39	cocrystal	cocrystal	ADJ
admet-505	286	40	solubility	solubility	NOUN
admet-505	286	41	-	-	PUNCT
admet-505	286	42	ph	ph	VERB
admet-505	286	43	,	,	PUNCT
admet-505	286	44	drug	drug	NOUN
admet-505	286	45	solubilization	solubilization	NOUN
admet-505	286	46	capacity	capacity	NOUN
admet-505	286	47	of	of	ADP
admet-505	286	48	sds	sds	PROPN
admet-505	286	49	,	,	PUNCT
admet-505	286	50	mass	mass	ADJ
admet-505	286	51	action	action	NOUN
admet-505	286	52	model	model	NOUN
admet-505	286	53	doi	doi	PROPN
admet-505	286	54	:	:	PUNCT
admet-505	286	55	10.5599	10.5599	NUM
admet-505	286	56	/	/	SYM
admet-505	286	57	admet.505	admet.505	PROPN
admet-505	286	58	109	109	NUM
admet-505	286	59	surfactant	surfactant	ADJ
admet-505	286	60	concentration	concentration	NOUN
admet-505	286	61	is	be	AUX
admet-505	286	62	increased	increase	VERB
admet-505	286	63	above	above	ADP
admet-505	286	64	the	the	DET
admet-505	286	65	cmc	cmc	NOUN
admet-505	286	66	.	.	PUNCT
admet-505	287	1	the	the	DET
admet-505	287	2	[	[	X
admet-505	287	3	na	na	X
admet-505	287	4	+	+	NUM
admet-505	287	5	]	]	PUNCT
admet-505	287	6	concentration	concentration	NOUN
admet-505	287	7	(	(	PUNCT
admet-505	287	8	off	off	ADP
admet-505	287	9	-	-	PUNCT
admet-505	287	10	scale	scale	NOUN
admet-505	287	11	)	)	PUNCT
admet-505	287	12	remains	remain	VERB
admet-505	287	13	nearly	nearly	ADV
admet-505	287	14	constant	constant	ADJ
admet-505	287	15	,	,	PUNCT
admet-505	287	16	at	at	ADP
admet-505	287	17	150	150	NUM
admet-505	287	18	-	-	SYM
admet-505	287	19	162	162	NUM
admet-505	287	20	mm	mm	NOUN
admet-505	287	21	.	.	PUNCT
admet-505	288	1	in	in	ADP
admet-505	288	2	frame	frame	NOUN
admet-505	288	3	(	(	PUNCT
admet-505	288	4	c	c	NOUN
admet-505	288	5	)	)	PUNCT
admet-505	288	6	,	,	PUNCT
admet-505	288	7	the	the	DET
admet-505	288	8	surfactant	surfactant	NOUN
admet-505	288	9	is	be	AUX
admet-505	288	10	added	add	VERB
admet-505	288	11	to	to	ADP
admet-505	288	12	a	a	DET
admet-505	288	13	50	50	NUM
admet-505	288	14	mm	mm	NOUN
admet-505	288	15	solution	solution	NOUN
admet-505	288	16	of	of	ADP
admet-505	288	17	phosphate	phosphate	ADJ
admet-505	288	18	buffer	buffer	NOUN
admet-505	288	19	at	at	ADP
admet-505	288	20	ph	ph	PROPN
admet-505	288	21	7	7	NUM
admet-505	288	22	.	.	PUNCT
admet-505	288	23	using	use	VERB
admet-505	288	24	the	the	DET
admet-505	288	25	same	same	ADJ
admet-505	288	26	ksds	ksds	NOUN
admet-505	288	27	in	in	ADP
admet-505	288	28	the	the	DET
admet-505	288	29	calculation	calculation	NOUN
admet-505	288	30	,	,	PUNCT
admet-505	288	31	cmc	cmc	NOUN
admet-505	288	32	=	=	SYM
admet-505	288	33	1.78	1.78	NUM
admet-505	288	34	mm	mm	NOUN
admet-505	288	35	.	.	PUNCT
admet-505	289	1	the	the	DET
admet-505	289	2	ionic	ionic	ADJ
admet-505	289	3	strength	strength	NOUN
admet-505	289	4	,	,	PUNCT
admet-505	289	5	which	which	PRON
admet-505	289	6	is	be	AUX
admet-505	289	7	intermediate	intermediate	ADJ
admet-505	289	8	between	between	ADP
admet-505	289	9	that	that	PRON
admet-505	289	10	of	of	ADP
admet-505	289	11	the	the	DET
admet-505	289	12	above	above	ADJ
admet-505	289	13	two	two	NUM
admet-505	289	14	cases	case	NOUN
admet-505	289	15	(	(	PUNCT
admet-505	289	16	cf	cf	NOUN
admet-505	289	17	.	.	PUNCT
admet-505	289	18	,	,	PUNCT
admet-505	289	19	fig	fig	NOUN
admet-505	289	20	.	.	PUNCT
admet-505	289	21	1d	1d	NUM
admet-505	289	22	)	)	PUNCT
admet-505	289	23	,	,	PUNCT
admet-505	289	24	clearly	clearly	ADV
admet-505	289	25	affects	affect	VERB
admet-505	289	26	the	the	DET
admet-505	289	27	cmc	cmc	NOUN
admet-505	289	28	.	.	PUNCT
admet-505	290	1	a	a	DET
admet-505	290	2	linear	linear	ADJ
admet-505	290	3	regression	regression	NOUN
admet-505	290	4	of	of	ADP
admet-505	290	5	the	the	DET
admet-505	290	6	above	above	ADJ
admet-505	290	7	three	three	NUM
admet-505	290	8	values	value	NOUN
admet-505	290	9	of	of	ADP
admet-505	290	10	log	log	NOUN
admet-505	290	11	cmc	cmc	NOUN
admet-505	290	12	vs.	vs.	ADP
admet-505	290	13	ionic	ionic	ADJ
admet-505	290	14	strength	strength	NOUN
admet-505	290	15	(	(	PUNCT
admet-505	290	16	icmc	icmc	ADJ
admet-505	290	17	,	,	PUNCT
admet-505	290	18	evaluated	evaluate	VERB
admet-505	290	19	at	at	ADP
admet-505	290	20	the	the	DET
admet-505	290	21	cmc	cmc	NOUN
admet-505	290	22	)	)	PUNCT
admet-505	290	23	produces	produce	VERB
admet-505	290	24	:	:	PUNCT
admet-505	290	25	log	log	NOUN
admet-505	290	26	cmc	cmc	NOUN
admet-505	290	27	=	=	PUNCT
admet-505	290	28	-3.56	-3.56	PUNCT
admet-505	290	29	0.73	0.73	NUM
admet-505	290	30	log	log	PROPN
admet-505	290	31	icmc	icmc	NOUN
admet-505	290	32	.	.	PUNCT
admet-505	291	1	a	a	DET
admet-505	291	2	similar	similar	ADJ
admet-505	291	3	relationship	relationship	NOUN
admet-505	291	4	,	,	PUNCT
admet-505	291	5	experimentally	experimentally	ADV
admet-505	291	6	-	-	PUNCT
admet-505	291	7	determined	determine	VERB
admet-505	291	8	by	by	ADP
admet-505	291	9	fuguet	fuguet	PROPN
admet-505	291	10	et	et	PROPN
admet-505	291	11	al	al	PROPN
admet-505	291	12	.	.	PUNCT
admet-505	292	1	[	[	X
admet-505	292	2	18	18	NUM
admet-505	292	3	]	]	PUNCT
admet-505	292	4	,	,	PUNCT
admet-505	292	5	is	be	AUX
admet-505	292	6	log	log	NOUN
admet-505	292	7	cmc	cmc	NOUN
admet-505	292	8	=	=	PUNCT
admet-505	292	9	3.23	3.23	NUM
admet-505	292	10	0.49	0.49	NUM
admet-505	292	11	log	log	NOUN
admet-505	292	12	ci	ci	NOUN
admet-505	292	13	,	,	PUNCT
admet-505	292	14	where	where	SCONJ
admet-505	292	15	ci	ci	PROPN
admet-505	292	16	is	be	AUX
admet-505	292	17	the	the	DET
admet-505	292	18	added	add	VERB
admet-505	292	19	counterion	counterion	NOUN
admet-505	292	20	concentration	concentration	NOUN
admet-505	292	21	(	(	PUNCT
admet-505	292	22	about	about	ADP
admet-505	292	23	1.5	1.5	NUM
admet-505	292	24	times	time	NOUN
admet-505	292	25	the	the	DET
admet-505	292	26	phosphate	phosphate	ADJ
admet-505	292	27	concentration	concentration	NOUN
admet-505	292	28	)	)	PUNCT
admet-505	292	29	.	.	PUNCT
admet-505	293	1	fuguet	fuguet	VERB
admet-505	293	2	et	et	PROPN
admet-505	293	3	al	al	PROPN
admet-505	293	4	.	.	PROPN
admet-505	293	5	used	use	VERB
admet-505	293	6	three	three	NUM
admet-505	293	7	different	different	ADJ
admet-505	293	8	methods	method	NOUN
admet-505	293	9	to	to	PART
admet-505	293	10	measure	measure	VERB
admet-505	293	11	cmc	cmc	PROPN
admet-505	293	12	.	.	PUNCT
admet-505	294	1	in	in	ADP
admet-505	294	2	distilled	distilled	ADJ
admet-505	294	3	water	water	NOUN
admet-505	294	4	,	,	PUNCT
admet-505	294	5	the	the	DET
admet-505	294	6	measured	measured	ADJ
admet-505	294	7	cmc	cmc	NOUN
admet-505	294	8	=	=	SYM
admet-505	294	9	8.08	8.08	NUM
admet-505	294	10	±	±	NUM
admet-505	294	11	0.12	0.12	NUM
admet-505	294	12	mm	mm	NOUN
admet-505	294	13	;	;	PUNCT
admet-505	294	14	in	in	ADP
admet-505	294	15	50	50	NUM
admet-505	294	16	mm	mm	NOUN
admet-505	294	17	phosphate	phosphate	NOUN
admet-505	294	18	buffer	buffer	NOUN
admet-505	294	19	(	(	PUNCT
admet-505	294	20	ph	ph	ADJ
admet-505	294	21	7	7	NUM
admet-505	294	22	)	)	PUNCT
admet-505	294	23	cmc	cmc	NOUN
admet-505	294	24	=	=	SYM
admet-505	294	25	1.99	1.99	NUM
admet-505	294	26	±	±	NUM
admet-505	294	27	0.02	0.02	NUM
admet-505	294	28	mm	mm	NOUN
admet-505	294	29	[	[	X
admet-505	294	30	18	18	NUM
admet-505	294	31	]	]	PUNCT
admet-505	294	32	.	.	PUNCT
admet-505	295	1	these	these	DET
admet-505	295	2	measured	measure	VERB
admet-505	295	3	values	value	NOUN
admet-505	295	4	are	be	AUX
admet-505	295	5	remarkably	remarkably	ADV
admet-505	295	6	similar	similar	ADJ
admet-505	295	7	to	to	ADP
admet-505	295	8	those	those	PRON
admet-505	295	9	derived	derive	VERB
admet-505	295	10	by	by	ADP
admet-505	295	11	purely	purely	ADV
admet-505	295	12	in	in	ADP
admet-505	295	13	silico	silico	NOUN
admet-505	295	14	mass	mass	NOUN
admet-505	295	15	action	action	NOUN
admet-505	295	16	simulations	simulation	NOUN
admet-505	295	17	with	with	ADP
admet-505	295	18	the	the	DET
admet-505	295	19	aggregation	aggregation	NOUN
admet-505	295	20	constant	constant	ADJ
admet-505	295	21	log	log	NOUN
admet-505	295	22	ksds	ksds	NOUN
admet-505	295	23	=	=	NOUN
admet-505	296	1	230.6	230.6	NUM
admet-505	296	2	.	.	PUNCT
admet-505	297	1	the	the	DET
admet-505	297	2	mass	mass	ADJ
admet-505	297	3	action	action	NOUN
admet-505	297	4	model	model	NOUN
admet-505	297	5	could	could	AUX
admet-505	297	6	be	be	AUX
admet-505	297	7	used	use	VERB
admet-505	297	8	to	to	PART
admet-505	297	9	try	try	VERB
admet-505	297	10	to	to	PART
admet-505	297	11	predict	predict	VERB
admet-505	297	12	many	many	ADJ
admet-505	297	13	of	of	ADP
admet-505	297	14	the	the	DET
admet-505	297	15	factors	factor	NOUN
admet-505	297	16	that	that	PRON
admet-505	297	17	make	make	VERB
admet-505	297	18	cmc	cmc	NOUN
admet-505	297	19	value	value	NOUN
admet-505	297	20	different	different	ADJ
admet-505	297	21	from	from	ADP
admet-505	297	22	that	that	PRON
admet-505	297	23	found	find	VERB
admet-505	297	24	in	in	ADP
admet-505	297	25	water	water	NOUN
admet-505	297	26	,	,	PUNCT
admet-505	297	27	such	such	ADJ
admet-505	297	28	as	as	ADP
admet-505	297	29	type	type	NOUN
admet-505	297	30	and	and	CCONJ
admet-505	297	31	amount	amount	NOUN
admet-505	297	32	of	of	ADP
admet-505	297	33	electrolytes	electrolyte	NOUN
admet-505	297	34	,	,	PUNCT
admet-505	297	35	ionic	ionic	ADJ
admet-505	297	36	strength	strength	NOUN
admet-505	297	37	,	,	PUNCT
admet-505	297	38	buffer	buffer	VERB
admet-505	297	39	ph	ph	VERB
admet-505	297	40	,	,	PUNCT
admet-505	297	41	temperature	temperature	NOUN
admet-505	297	42	,	,	PUNCT
admet-505	297	43	and	and	CCONJ
admet-505	297	44	added	add	VERB
admet-505	297	45	drugs	drug	NOUN
admet-505	297	46	.	.	PUNCT
admet-505	298	1	some	some	DET
admet-505	298	2	examples	example	NOUN
admet-505	298	3	of	of	ADP
admet-505	298	4	this	this	PRON
admet-505	298	5	will	will	AUX
admet-505	298	6	be	be	AUX
admet-505	298	7	explored	explore	VERB
admet-505	298	8	below	below	ADV
admet-505	298	9	.	.	PUNCT
admet-505	299	1	in	in	ADP
admet-505	299	2	the	the	DET
admet-505	299	3	simulations	simulation	NOUN
admet-505	299	4	,	,	PUNCT
admet-505	299	5	it	it	PRON
admet-505	299	6	was	be	AUX
admet-505	299	7	found	find	VERB
admet-505	299	8	that	that	SCONJ
admet-505	299	9	ph	ph	NOUN
admet-505	299	10	could	could	AUX
admet-505	299	11	be	be	AUX
admet-505	299	12	used	use	VERB
admet-505	299	13	to	to	PART
admet-505	299	14	indicate	indicate	VERB
admet-505	299	15	cmc	cmc	NOUN
admet-505	299	16	,	,	PUNCT
admet-505	299	17	as	as	SCONJ
admet-505	299	18	shown	show	VERB
admet-505	299	19	in	in	ADP
admet-505	299	20	figure	figure	NOUN
admet-505	299	21	1d	1d	NUM
admet-505	299	22	for	for	ADP
admet-505	299	23	the	the	DET
admet-505	299	24	pure	pure	ADJ
admet-505	299	25	water	water	NOUN
admet-505	299	26	case	case	NOUN
admet-505	299	27	(	(	PUNCT
admet-505	299	28	dash	dash	NOUN
admet-505	299	29	-	-	PUNCT
admet-505	299	30	dot	dot	NOUN
admet-505	299	31	curve	curve	NOUN
admet-505	299	32	)	)	PUNCT
admet-505	299	33	.	.	PUNCT
admet-505	300	1	the	the	DET
admet-505	300	2	figure	figure	NOUN
admet-505	300	3	also	also	ADV
admet-505	300	4	indicates	indicate	VERB
admet-505	300	5	that	that	SCONJ
admet-505	300	6	the	the	DET
admet-505	300	7	ionic	ionic	ADJ
admet-505	300	8	strength	strength	NOUN
admet-505	300	9	increases	increase	VERB
admet-505	300	10	nearly	nearly	ADV
admet-505	300	11	linearly	linearly	ADV
admet-505	300	12	with	with	SCONJ
admet-505	300	13	total	total	ADJ
admet-505	300	14	surfactant	surfactant	NOUN
admet-505	300	15	added	add	VERB
admet-505	300	16	.	.	PUNCT
admet-505	301	1	the	the	DET
admet-505	301	2	pdisol	pdisol	ADJ
admet-505	301	3	-	-	PUNCT
admet-505	301	4	x	x	NOUN
admet-505	301	5	calculation	calculation	NOUN
admet-505	301	6	adjusts	adjust	VERB
admet-505	301	7	both	both	DET
admet-505	301	8	equilibrium	equilibrium	NOUN
admet-505	301	9	constants	constant	NOUN
admet-505	301	10	and	and	CCONJ
admet-505	301	11	ph	ph	ADJ
admet-505	301	12	electrode	electrode	NOUN
admet-505	301	13	calibration	calibration	NOUN
admet-505	301	14	parameters	parameter	NOUN
admet-505	301	15	for	for	ADP
admet-505	301	16	changes	change	NOUN
admet-505	301	17	in	in	ADP
admet-505	301	18	ionic	ionic	ADJ
admet-505	301	19	strength	strength	NOUN
admet-505	301	20	.	.	PUNCT
admet-505	302	1	molar	molar	ADJ
admet-505	302	2	solubilization	solubilization	NOUN
admet-505	302	3	capacity	capacity	NOUN
admet-505	302	4	(	(	PUNCT
admet-505	302	5	k	k	NOUN
admet-505	302	6	)	)	PUNCT
admet-505	302	7	and	and	CCONJ
admet-505	302	8	the	the	DET
admet-505	302	9	drug	drug	NOUN
admet-505	302	10	-	-	PUNCT
admet-505	302	11	micelle	micelle	NOUN
admet-505	302	12	binding	bind	VERB
admet-505	302	13	constant	constant	ADJ
admet-505	302	14	,	,	PUNCT
admet-505	302	15	kn	kn	PROPN
admet-505	302	16	the	the	DET
admet-505	302	17	solubilization	solubilization	NOUN
admet-505	302	18	capacity	capacity	NOUN
admet-505	302	19	(	(	PUNCT
admet-505	302	20	k	k	NOUN
admet-505	302	21	)	)	PUNCT
admet-505	302	22	of	of	ADP
admet-505	302	23	a	a	DET
admet-505	302	24	sparingly	sparingly	ADV
admet-505	302	25	-	-	PUNCT
admet-505	302	26	soluble	soluble	ADJ
admet-505	302	27	drug	drug	NOUN
admet-505	302	28	can	can	AUX
admet-505	302	29	be	be	AUX
admet-505	302	30	simply	simply	ADV
admet-505	302	31	measured	measure	VERB
admet-505	302	32	.	.	PUNCT
admet-505	303	1	the	the	DET
admet-505	303	2	observed	observed	ADJ
admet-505	303	3	total	total	ADJ
admet-505	303	4	solubility	solubility	NOUN
admet-505	303	5	of	of	ADP
admet-505	303	6	the	the	DET
admet-505	303	7	drug	drug	NOUN
admet-505	303	8	is	be	AUX
admet-505	303	9	plotted	plot	VERB
admet-505	303	10	against	against	ADP
admet-505	303	11	the	the	DET
admet-505	303	12	total	total	ADJ
admet-505	303	13	added	add	VERB
admet-505	303	14	surfactant	surfactant	ADJ
admet-505	303	15	concentration	concentration	NOUN
admet-505	303	16	.	.	PUNCT
admet-505	304	1	for	for	ADP
admet-505	304	2	[	[	X
admet-505	304	3	sds]tot	sds]tot	NOUN
admet-505	304	4	>	>	X
admet-505	304	5	cmc	cmc	NOUN
admet-505	304	6	,	,	PUNCT
admet-505	304	7	the	the	DET
admet-505	304	8	curve	curve	NOUN
admet-505	304	9	is	be	AUX
admet-505	304	10	usually	usually	ADV
admet-505	304	11	linear	linear	ADJ
admet-505	304	12	:	:	PUNCT
admet-505	304	13	the	the	DET
admet-505	304	14	slope	slope	NOUN
admet-505	304	15	in	in	ADP
admet-505	304	16	this	this	DET
admet-505	304	17	region	region	NOUN
admet-505	304	18	is	be	AUX
admet-505	304	19	the	the	DET
admet-505	304	20	k	k	PROPN
admet-505	304	21	value	value	NOUN
admet-505	304	22	.	.	PUNCT
admet-505	305	1	as	as	ADP
admet-505	305	2	a	a	DET
admet-505	305	3	simplified	simplified	ADJ
admet-505	305	4	example	example	NOUN
admet-505	305	5	of	of	ADP
admet-505	305	6	the	the	DET
admet-505	305	7	mass	mass	ADJ
admet-505	305	8	action	action	NOUN
admet-505	305	9	methodology	methodology	NOUN
admet-505	305	10	,	,	PUNCT
admet-505	305	11	consider	consider	VERB
admet-505	305	12	the	the	DET
admet-505	305	13	following	follow	VERB
admet-505	305	14	chemical	chemical	ADJ
admet-505	305	15	equilibria	equilibrium	NOUN
admet-505	305	16	involving	involve	VERB
admet-505	305	17	sds	sds	PROPN
admet-505	305	18	and	and	CCONJ
admet-505	305	19	a	a	DET
admet-505	305	20	basic	basic	ADJ
admet-505	305	21	drug	drug	NOUN
admet-505	305	22	,	,	PUNCT
admet-505	305	23	b	b	NOUN
admet-505	305	24	,	,	PUNCT
admet-505	305	25	which	which	PRON
admet-505	305	26	has	have	VERB
admet-505	305	27	a	a	DET
admet-505	305	28	single	single	ADJ
admet-505	305	29	pka	pka	NOUN
admet-505	305	30	,	,	PUNCT
admet-505	305	31	well	well	ADV
admet-505	305	32	below	below	ADP
admet-505	305	33	7	7	NUM
admet-505	305	34	.	.	PUNCT
admet-505	306	1	consider	consider	VERB
admet-505	306	2	also	also	ADV
admet-505	306	3	that	that	SCONJ
admet-505	306	4	enough	enough	ADJ
admet-505	306	5	surfactant	surfactant	NOUN
admet-505	306	6	is	be	AUX
admet-505	306	7	added	add	VERB
admet-505	306	8	to	to	PART
admet-505	306	9	water	water	VERB
admet-505	306	10	that	that	SCONJ
admet-505	306	11	[	[	X
admet-505	306	12	sds]tot	sds]tot	NOUN
admet-505	306	13	>	>	X
admet-505	306	14	cmc	cmc	NOUN
admet-505	306	15	.	.	PUNCT
admet-505	307	1	the	the	DET
admet-505	307	2	total	total	ADJ
admet-505	307	3	micelle	micelle	NOUN
admet-505	307	4	concentration	concentration	NOUN
admet-505	307	5	,	,	PUNCT
admet-505	308	1	[	[	X
admet-505	308	2	mic]tot	mic]tot	X
admet-505	308	3	=	=	X
admet-505	308	4	(	(	PUNCT
admet-505	308	5	[	[	X
admet-505	308	6	sds]tot	sds]tot	NOUN
admet-505	308	7	–	–	PUNCT
admet-505	308	8	cmc)/nagg	cmc)/nagg	NOUN
admet-505	308	9	.	.	PUNCT
admet-505	309	1	bh+	bh+	PROPN
admet-505	309	2			PROPN
admet-505	310	1	b	b	PROPN
admet-505	310	2	+	+	CCONJ
admet-505	310	3	h+	h+	X
admet-505	310	4	ka	ka	PROPN
admet-505	310	5	=	=	PUNCT
admet-505	311	1	[	[	X
admet-505	311	2	b][h+	b][h+	X
admet-505	311	3	]	]	X
admet-505	311	4	/	/	PUNCT
admet-505	311	5	[	[	X
admet-505	311	6	bh+	bh+	NOUN
admet-505	311	7	]	]	X
admet-505	311	8	(	(	PUNCT
admet-505	311	9	2	2	X
admet-505	311	10	)	)	PUNCT
admet-505	311	11	nb	nb	NOUN
admet-505	312	1	+	+	CCONJ
admet-505	312	2	mic12	mic12	NOUN
admet-505	312	3			NOUN
admet-505	312	4	bnmic12	bnmic12	NOUN
admet-505	312	5	kn	kn	NOUN
admet-505	313	1	=	=	PUNCT
admet-505	314	1	[	[	X
admet-505	314	2	bnmic12	bnmic12	NOUN
admet-505	314	3	]	]	PUNCT
admet-505	314	4	/	/	PUNCT
admet-505	315	1	[	[	X
admet-505	315	2	b	b	X
admet-505	315	3	]	]	X
admet-505	315	4	n[mic12	n[mic12	NOUN
admet-505	315	5	]	]	X
admet-505	315	6	(	(	PUNCT
admet-505	315	7	3	3	X
admet-505	315	8	)	)	PUNCT
admet-505	315	9	b(s	b(	NOUN
admet-505	315	10	)	)	PUNCT
admet-505	315	11			X
admet-505	316	1	b	b	X
admet-505	316	2	s0	s0	X
admet-505	316	3	=	=	PUNCT
admet-505	317	1	[	[	X
admet-505	317	2	b	b	X
admet-505	317	3	]	]	X
admet-505	317	4	(	(	PUNCT
admet-505	317	5	4	4	X
admet-505	317	6	)	)	PUNCT
admet-505	317	7	kn	kn	PROPN
admet-505	317	8	is	be	AUX
admet-505	317	9	the	the	DET
admet-505	317	10	drug	drug	NOUN
admet-505	317	11	-	-	PUNCT
admet-505	317	12	micelle	micelle	NOUN
admet-505	317	13	binding	bind	VERB
admet-505	317	14	constant	constant	ADJ
admet-505	317	15	,	,	PUNCT
admet-505	317	16	where	where	SCONJ
admet-505	317	17	n	n	PRON
admet-505	317	18	refers	refer	VERB
admet-505	317	19	to	to	ADP
admet-505	317	20	the	the	DET
admet-505	317	21	number	number	NOUN
admet-505	317	22	of	of	ADP
admet-505	317	23	drug	drug	NOUN
admet-505	317	24	molecules	molecule	NOUN
admet-505	317	25	bound	bind	VERB
admet-505	317	26	to	to	ADP
admet-505	317	27	a	a	DET
admet-505	317	28	micelle	micelle	NOUN
admet-505	317	29	,	,	PUNCT
admet-505	317	30	and	and	CCONJ
admet-505	317	31	s0	s0	NOUN
admet-505	317	32	is	be	AUX
admet-505	317	33	the	the	DET
admet-505	317	34	intrinsic	intrinsic	ADJ
admet-505	317	35	solubility	solubility	NOUN
admet-505	317	36	of	of	ADP
admet-505	317	37	the	the	DET
admet-505	317	38	drug	drug	NOUN
admet-505	317	39	(	(	PUNCT
admet-505	317	40	cf	cf	NOUN
admet-505	317	41	.	.	PUNCT
admet-505	317	42	,	,	PUNCT
admet-505	317	43	glossary	glossary	NOUN
admet-505	317	44	)	)	PUNCT
admet-505	317	45	.	.	PUNCT
admet-505	318	1	if	if	SCONJ
admet-505	318	2	the	the	DET
admet-505	318	3	concentration	concentration	NOUN
admet-505	318	4	of	of	ADP
admet-505	318	5	the	the	DET
admet-505	318	6	drug	drug	NOUN
admet-505	318	7	is	be	AUX
admet-505	318	8	kept	keep	VERB
admet-505	318	9	below	below	ADP
admet-505	318	10	its	its	PRON
admet-505	318	11	intrinsic	intrinsic	ADJ
admet-505	318	12	solubility	solubility	NOUN
admet-505	318	13	,	,	PUNCT
admet-505	318	14	then	then	ADV
admet-505	318	15	eq	eq	ADP
admet-505	318	16	.	.	PUNCT
admet-505	319	1	(	(	PUNCT
admet-505	319	2	4	4	X
admet-505	319	3	)	)	PUNCT
admet-505	319	4	need	need	AUX
admet-505	319	5	not	not	PART
admet-505	319	6	be	be	AUX
admet-505	319	7	considered	consider	VERB
admet-505	319	8	.	.	PUNCT
admet-505	320	1	in	in	ADP
admet-505	320	2	such	such	DET
admet-505	320	3	a	a	DET
admet-505	320	4	homogeneous	homogeneous	ADJ
admet-505	320	5	micellar	micellar	NOUN
admet-505	320	6	solution	solution	NOUN
admet-505	320	7	,	,	PUNCT
admet-505	320	8	the	the	DET
admet-505	320	9	three	three	NUM
admet-505	320	10	independent	independent	ADJ
admet-505	320	11	reactants	reactant	NOUN
admet-505	320	12	are	be	AUX
admet-505	320	13	b	b	NOUN
admet-505	320	14	,	,	PUNCT
admet-505	320	15	mic12-	mic12-	PROPN
admet-505	320	16	,	,	PUNCT
admet-505	320	17	and	and	CCONJ
admet-505	320	18	h+	h+	X
admet-505	320	19	.	.	PUNCT
admet-505	321	1	the	the	DET
admet-505	321	2	corresponding	correspond	VERB
admet-505	321	3	mass	mass	NOUN
admet-505	321	4	balance	balance	NOUN
admet-505	321	5	equations	equation	NOUN
admet-505	321	6	may	may	AUX
admet-505	321	7	be	be	AUX
admet-505	321	8	stated	state	VERB
admet-505	321	9	as	as	ADP
admet-505	321	10	:	:	PUNCT
admet-505	321	11	[	[	X
admet-505	321	12	b]tot	b]tot	X
admet-505	321	13	=	=	X
admet-505	322	1	[	[	X
admet-505	322	2	b	b	X
admet-505	322	3	]	]	X
admet-505	322	4	+	+	CCONJ
admet-505	322	5	[	[	X
admet-505	322	6	bh+	bh+	NOUN
admet-505	322	7	]	]	X
admet-505	322	8	+	+	PUNCT
admet-505	322	9	n[bnmic12	n[bnmic12	NOUN
admet-505	322	10	]	]	X
admet-505	322	11	(	(	PUNCT
admet-505	322	12	5	5	X
admet-505	322	13	)	)	PUNCT
admet-505	323	1	[	[	X
admet-505	323	2	mic]tot	mic]tot	X
admet-505	323	3	=	=	PUNCT
admet-505	324	1	[	[	X
admet-505	324	2	mic12-	mic12-	X
admet-505	324	3	]	]	X
admet-505	324	4	+	+	CCONJ
admet-505	324	5	[	[	X
admet-505	324	6	bnmic12	bnmic12	NOUN
admet-505	324	7	]	]	PUNCT
admet-505	324	8	(	(	PUNCT
admet-505	324	9	6	6	NUM
admet-505	324	10	)	)	PUNCT
admet-505	325	1	[	[	X
admet-505	325	2	h]tot	h]tot	X
admet-505	325	3	=	=	X
admet-505	326	1	[	[	X
admet-505	326	2	h+	h+	X
admet-505	326	3	]	]	X
admet-505	326	4	–	–	PUNCT
admet-505	326	5	kw	kw	INTJ
admet-505	326	6	/	/	PUNCT
admet-505	327	1	[	[	X
admet-505	328	1	h+	h+	X
admet-505	328	2	]	]	X
admet-505	328	3	+	+	CCONJ
admet-505	328	4	[	[	X
admet-505	328	5	bh+	bh+	NOUN
admet-505	328	6	]	]	PUNCT
admet-505	328	7	.	.	PUNCT
admet-505	329	1	(	(	PUNCT
admet-505	329	2	7	7	X
admet-505	329	3	)	)	PUNCT
admet-505	329	4	kw	kw	PROPN
admet-505	329	5	is	be	AUX
admet-505	329	6	the	the	DET
admet-505	329	7	ionization	ionization	NOUN
admet-505	329	8	constant	constant	ADJ
admet-505	329	9	of	of	ADP
admet-505	329	10	water	water	NOUN
admet-505	329	11	.	.	PUNCT
admet-505	330	1	eq	eq	ADJ
admet-505	330	2	.	.	PUNCT
admet-505	331	1	(	(	PUNCT
admet-505	331	2	7	7	X
admet-505	331	3	)	)	PUNCT
admet-505	331	4	is	be	AUX
admet-505	331	5	the	the	DET
admet-505	331	6	hydrogen	hydrogen	NOUN
admet-505	331	7	excess	excess	NOUN
admet-505	331	8	,	,	PUNCT
admet-505	331	9	which	which	PRON
admet-505	331	10	can	can	AUX
admet-505	331	11	be	be	AUX
admet-505	331	12	negative	negative	ADJ
admet-505	331	13	in	in	ADP
admet-505	331	14	alkaline	alkaline	NOUN
admet-505	331	15	solutions	solution	NOUN
admet-505	331	16	.	.	PUNCT
admet-505	332	1	on	on	ADP
admet-505	332	2	substituting	substitute	VERB
admet-505	332	3	the	the	DET
admet-505	332	4	equilibrium	equilibrium	NOUN
admet-505	332	5	quotients	quotient	NOUN
admet-505	332	6	from	from	ADP
admet-505	332	7	eqs	eqs	PROPN
admet-505	332	8	.	.	PUNCT
admet-505	333	1	(	(	PUNCT
admet-505	333	2	2	2	NUM
admet-505	333	3	)	)	PUNCT
admet-505	333	4	and	and	CCONJ
admet-505	333	5	(	(	PUNCT
admet-505	333	6	3	3	X
admet-505	333	7	)	)	PUNCT
admet-505	333	8	into	into	ADP
admet-505	333	9	the	the	DET
admet-505	333	10	mass	mass	NOUN
admet-505	333	11	balance	balance	NOUN
admet-505	333	12	equations	equation	NOUN
admet-505	333	13	,	,	PUNCT
admet-505	333	14	alex	alex	PROPN
admet-505	333	15	avdeef	avdeef	PROPN
admet-505	333	16	admet	admet	PROPN
admet-505	333	17	&	&	CCONJ
admet-505	333	18	dmpk	dmpk	PROPN
admet-505	333	19	6(2	6(2	NUM
admet-505	333	20	)	)	PUNCT
admet-505	333	21	(	(	PUNCT
admet-505	333	22	2018	2018	NUM
admet-505	333	23	)	)	PUNCT
admet-505	333	24	105	105	NUM
admet-505	333	25	-	-	SYM
admet-505	333	26	139	139	NUM
admet-505	333	27	110	110	NUM
admet-505	333	28	one	one	NOUN
admet-505	333	29	gets	get	VERB
admet-505	333	30	three	three	NUM
admet-505	333	31	polynomials	polynomial	NOUN
admet-505	333	32	as	as	ADP
admet-505	333	33	a	a	DET
admet-505	333	34	function	function	NOUN
admet-505	333	35	of	of	ADP
admet-505	333	36	the	the	DET
admet-505	333	37	three	three	NUM
admet-505	333	38	reactants	reactant	NOUN
admet-505	333	39	(	(	PUNCT
admet-505	333	40	b	b	NOUN
admet-505	333	41	,	,	PUNCT
admet-505	333	42	mic	mic	ADJ
admet-505	333	43	12	12	NUM
admet-505	333	44	,	,	PUNCT
admet-505	333	45	and	and	CCONJ
admet-505	333	46	h	h	NOUN
admet-505	334	1	+	+	CCONJ
admet-505	334	2	)	)	PUNCT
admet-505	334	3	and	and	CCONJ
admet-505	334	4	the	the	DET
admet-505	334	5	equilibrium	equilibrium	NOUN
admet-505	334	6	constants	constant	NOUN
admet-505	334	7	ka	ka	PROPN
admet-505	334	8	,	,	PUNCT
admet-505	334	9	kw	kw	PROPN
admet-505	334	10	,	,	PUNCT
admet-505	334	11	and	and	CCONJ
admet-505	334	12	kn	kn	PROPN
admet-505	334	13	.	.	PUNCT
admet-505	335	1	[	[	X
admet-505	335	2	b]tot	b]tot	NOUN
admet-505	335	3	=	=	X
admet-505	335	4	[	[	X
admet-505	335	5	b	b	X
admet-505	335	6	]	]	X
admet-505	335	7	+	+	CCONJ
admet-505	336	1	[	[	X
admet-505	336	2	b][h	b][h	X
admet-505	336	3	+	+	X
admet-505	336	4	]	]	PUNCT
admet-505	336	5	/ka	/ka	X
admet-505	336	6	+	+	NUM
admet-505	336	7	nkn	nkn	PROPN
admet-505	337	1	[	[	X
admet-505	337	2	b	b	X
admet-505	337	3	]	]	X
admet-505	337	4	n	n	CCONJ
admet-505	338	1	[	[	X
admet-505	338	2	mic	mic	ADJ
admet-505	338	3	12	12	NUM
admet-505	338	4	]	]	PUNCT
admet-505	338	5	(	(	PUNCT
admet-505	338	6	8)	8)	NUM
admet-505	338	7	[	[	X
admet-505	338	8	mic]tot	mic]tot	NOUN
admet-505	338	9	=	=	PUNCT
admet-505	339	1	[	[	X
admet-505	339	2	mic	mic	ADJ
admet-505	339	3	12	12	NUM
admet-505	339	4	]	]	PUNCT
admet-505	340	1	+	+	CCONJ
admet-505	340	2	kn	kn	PROPN
admet-505	341	1	[	[	X
admet-505	341	2	b	b	X
admet-505	341	3	]	]	X
admet-505	341	4	n	n	CCONJ
admet-505	342	1	[	[	X
admet-505	342	2	mic	mic	ADJ
admet-505	342	3	12	12	NUM
admet-505	342	4	]	]	PUNCT
admet-505	342	5	(	(	PUNCT
admet-505	342	6	9	9	X
admet-505	342	7	)	)	PUNCT
admet-505	343	1	[	[	X
admet-505	343	2	h]tot	h]tot	X
admet-505	343	3	=	=	X
admet-505	344	1	[	[	X
admet-505	344	2	h	h	NOUN
admet-505	344	3	+	+	X
admet-505	344	4	]	]	PUNCT
admet-505	344	5	–	–	PUNCT
admet-505	344	6	kw	kw	INTJ
admet-505	344	7	/	/	PUNCT
admet-505	345	1	[	[	X
admet-505	345	2	h	h	NOUN
admet-505	345	3	+	+	X
admet-505	345	4	]	]	PUNCT
admet-505	346	1	+	+	CCONJ
admet-505	347	1	[	[	X
admet-505	347	2	b][h	b][h	X
admet-505	347	3	+	+	X
admet-505	347	4	]	]	X
admet-505	347	5	/ka	/ka	PUNCT
admet-505	347	6	.	.	PUNCT
admet-505	348	1	(	(	PUNCT
admet-505	348	2	10	10	NUM
admet-505	348	3	)	)	PUNCT
admet-505	348	4	the	the	PRON
admet-505	349	1	[	[	X
admet-505	349	2	b	b	X
admet-505	349	3	]	]	X
admet-505	349	4	,	,	PUNCT
admet-505	349	5	[	[	X
admet-505	349	6	mic	mic	ADJ
admet-505	349	7	12	12	NUM
admet-505	349	8	]	]	PUNCT
admet-505	349	9	,	,	PUNCT
admet-505	349	10	and	and	CCONJ
admet-505	349	11	[	[	X
admet-505	349	12	h	h	NOUN
admet-505	349	13	+	+	X
admet-505	349	14	]	]	PUNCT
admet-505	349	15	roots	root	NOUN
admet-505	349	16	of	of	ADP
admet-505	349	17	the	the	DET
admet-505	349	18	above	above	ADJ
admet-505	349	19	equations	equation	NOUN
admet-505	349	20	,	,	PUNCT
admet-505	349	21	as	as	ADV
admet-505	349	22	well	well	ADV
admet-505	349	23	as	as	ADP
admet-505	349	24	the	the	DET
admet-505	349	25	kn	kn	PROPN
admet-505	349	26	constant	constant	ADJ
admet-505	349	27	,	,	PUNCT
admet-505	349	28	are	be	AUX
admet-505	349	29	solved	solve	VERB
admet-505	349	30	using	use	VERB
admet-505	349	31	standard	standard	ADJ
admet-505	349	32	mathematical	mathematical	ADJ
admet-505	349	33	techniques	technique	NOUN
admet-505	350	1	[	[	X
admet-505	350	2	16	16	NUM
admet-505	350	3	,	,	PUNCT
admet-505	350	4	17	17	NUM
admet-505	350	5	]	]	PUNCT
admet-505	350	6	.	.	PUNCT
admet-505	351	1	kw	kw	INTJ
admet-505	351	2	and	and	CCONJ
admet-505	351	3	ka	ka	PROPN
admet-505	351	4	are	be	AUX
admet-505	351	5	generally	generally	ADV
admet-505	351	6	provided	provide	VERB
admet-505	351	7	as	as	ADP
admet-505	351	8	fixed	fix	VERB
admet-505	351	9	parameters	parameter	NOUN
admet-505	351	10	in	in	ADP
admet-505	351	11	the	the	DET
admet-505	351	12	calculation	calculation	NOUN
admet-505	351	13	.	.	PUNCT
admet-505	352	1	if	if	SCONJ
admet-505	352	2	the	the	DET
admet-505	352	3	drug	drug	NOUN
admet-505	352	4	precipitates	precipitate	NOUN
admet-505	352	5	in	in	ADP
admet-505	352	6	the	the	DET
admet-505	352	7	micellar	micellar	ADJ
admet-505	352	8	medium	medium	NOUN
admet-505	352	9	,	,	PUNCT
admet-505	352	10	then	then	ADV
admet-505	352	11	the	the	DET
admet-505	352	12	calculation	calculation	NOUN
admet-505	352	13	needs	need	VERB
admet-505	352	14	to	to	PART
admet-505	352	15	incorporate	incorporate	VERB
admet-505	352	16	eq	eq	ADP
admet-505	352	17	.	.	PUNCT
admet-505	353	1	(	(	PUNCT
admet-505	353	2	4	4	NUM
admet-505	353	3	)	)	PUNCT
admet-505	353	4	,	,	PUNCT
admet-505	353	5	as	as	SCONJ
admet-505	353	6	described	describe	VERB
admet-505	353	7	in	in	ADP
admet-505	353	8	detail	detail	NOUN
admet-505	353	9	elsewhere	elsewhere	ADV
admet-505	354	1	[	[	X
admet-505	354	2	16	16	NUM
admet-505	354	3	]	]	PUNCT
admet-505	354	4	.	.	PUNCT
admet-505	355	1	in	in	ADP
admet-505	355	2	the	the	DET
admet-505	355	3	aqueous	aqueous	ADJ
admet-505	355	4	-	-	PUNCT
admet-505	355	5	micellar	micellar	NOUN
admet-505	355	6	-	-	PUNCT
admet-505	355	7	solid	solid	ADJ
admet-505	355	8	medium	medium	NOUN
admet-505	355	9	eq	eq	NOUN
admet-505	355	10	.	.	PUNCT
admet-505	356	1	(	(	PUNCT
admet-505	356	2	8)	8)	NUM
admet-505	356	3	defines	define	VERB
admet-505	356	4	the	the	DET
admet-505	356	5	total	total	ADJ
admet-505	356	6	solubility	solubility	NOUN
admet-505	356	7	as	as	ADP
admet-505	356	8	a	a	DET
admet-505	356	9	function	function	NOUN
admet-505	356	10	of	of	ADP
admet-505	356	11	ph	ph	NOUN
admet-505	356	12	and	and	CCONJ
admet-505	356	13	the	the	DET
admet-505	356	14	extent	extent	NOUN
admet-505	356	15	of	of	ADP
admet-505	356	16	drug	drug	NOUN
admet-505	356	17	-	-	PUNCT
admet-505	356	18	micelle	micelle	NOUN
admet-505	356	19	binding	binding	NOUN
admet-505	356	20	,	,	PUNCT
admet-505	356	21	with	with	ADP
admet-505	356	22	[	[	X
admet-505	356	23	b	b	X
admet-505	356	24	]	]	X
admet-505	356	25	=	=	SYM
admet-505	356	26	s0	s0	PROPN
admet-505	356	27	.	.	PUNCT
admet-505	357	1	stot	stot	PROPN
admet-505	357	2	=	=	PROPN
admet-505	357	3	s0	s0	PROPN
admet-505	357	4	(	(	PUNCT
admet-505	357	5	1	1	NUM
admet-505	357	6	+	+	NUM
admet-505	357	7	10	10	NUM
admet-505	357	8	–	–	PUNCT
admet-505	357	9	ph	ph	ADJ
admet-505	357	10	+	+	X
admet-505	357	11	pka	pka	NOUN
admet-505	357	12	)	)	PUNCT
admet-505	358	1	+	+	CCONJ
admet-505	358	2	nkn	nkn	PROPN
admet-505	358	3	s0	s0	PROPN
admet-505	358	4	n	n	CCONJ
admet-505	358	5	[	[	X
admet-505	358	6	mic12	mic12	X
admet-505	358	7	]	]	X
admet-505	358	8	=	=	SYM
admet-505	358	9	s0	s0	X
admet-505	358	10	(	(	PUNCT
admet-505	358	11	1	1	NUM
admet-505	358	12	+	+	NUM
admet-505	358	13	10	10	NUM
admet-505	358	14	–	–	PUNCT
admet-505	358	15	ph	ph	ADJ
admet-505	358	16	+	+	X
admet-505	358	17	pka	pka	NOUN
admet-505	358	18	)	)	PUNCT
admet-505	359	1	+	+	CCONJ
admet-505	359	2	nkn	nkn	PROPN
admet-505	359	3	s0	s0	PROPN
admet-505	359	4	n	n	PROPN
admet-505	359	5	/(1	/(1	PUNCT
admet-505	360	1	+	+	CCONJ
admet-505	360	2	kn	kn	PROPN
admet-505	360	3	s0	s0	PROPN
admet-505	360	4	n	n	CCONJ
admet-505	360	5	)	)	PUNCT
admet-505	361	1	[	[	X
admet-505	361	2	mic]tot	mic]tot	X
admet-505	361	3	=	=	SYM
admet-505	361	4	s0	s0	PROPN
admet-505	361	5	(	(	PUNCT
admet-505	361	6	1	1	NUM
admet-505	361	7	+	+	NUM
admet-505	361	8	10	10	NUM
admet-505	361	9	–	–	PUNCT
admet-505	361	10	ph	ph	ADJ
admet-505	361	11	+	+	X
admet-505	361	12	pka	pka	NOUN
admet-505	361	13	)	)	PUNCT
admet-505	362	1	+	+	CCONJ
admet-505	362	2	nkn	nkn	PROPN
admet-505	362	3	s0	s0	PROPN
admet-505	362	4	n	n	PROPN
admet-505	362	5	/(1	/(1	PUNCT
admet-505	363	1	+	+	CCONJ
admet-505	363	2	kn	kn	PROPN
admet-505	363	3	s0	s0	PROPN
admet-505	363	4	n	n	CCONJ
admet-505	363	5	)	)	PUNCT
admet-505	363	6	{	{	PUNCT
admet-505	364	1	[	[	X
admet-505	364	2	sds]tot	sds]tot	NOUN
admet-505	364	3	–	–	PUNCT
admet-505	364	4	cmc	cmc	NOUN
admet-505	364	5	}	}	PUNCT
admet-505	364	6	/nagg	/nagg	INTJ
admet-505	364	7	.	.	PUNCT
admet-505	365	1	(	(	PUNCT
admet-505	365	2	11	11	NUM
admet-505	365	3	)	)	PUNCT
admet-505	365	4	for[sds]tot	for[sds]tot	NOUN
admet-505	365	5	>	>	X
admet-505	365	6	cmc	cmc	PROPN
admet-505	365	7	,	,	PUNCT
admet-505	365	8	the	the	DET
admet-505	365	9	first	first	ADJ
admet-505	365	10	derivative	derivative	ADJ
admet-505	365	11	dstot	dstot	NOUN
admet-505	365	12	/d[sds]tot	/d[sds]tot	X
admet-505	365	13	of	of	ADP
admet-505	365	14	the	the	DET
admet-505	365	15	above	above	ADJ
admet-505	365	16	equation	equation	NOUN
admet-505	365	17	defines	define	VERB
admet-505	365	18	k.	k.	X
admet-505	365	19	k	k	PROPN
admet-505	366	1	=	=	PUNCT
admet-505	366	2	n	n	CCONJ
admet-505	366	3	kn	kn	PROPN
admet-505	366	4	s0	s0	PROPN
admet-505	366	5	n	n	PROPN
admet-505	366	6	/	/	SYM
admet-505	366	7	{	{	PUNCT
admet-505	366	8	(	(	PUNCT
admet-505	366	9	1	1	NUM
admet-505	366	10	+	+	NUM
admet-505	366	11	kn	kn	PROPN
admet-505	366	12	s0	s0	PROPN
admet-505	366	13	n	n	CCONJ
admet-505	366	14	)	)	PUNCT
admet-505	366	15	nagg	nagg	NOUN
admet-505	366	16	}	}	PUNCT
admet-505	366	17	=	=	SYM
admet-505	366	18	n	n	CCONJ
admet-505	366	19	fbm	fbm	NOUN
admet-505	366	20	/	/	SYM
admet-505	366	21	nagg	nagg	PROPN
admet-505	366	22	=	=	NOUN
admet-505	366	23	nd	nd	INTJ
admet-505	366	24	/nagg	/nagg	INTJ
admet-505	366	25	(	(	PUNCT
admet-505	366	26	12	12	NUM
admet-505	366	27	)	)	PUNCT
admet-505	366	28	the	the	DET
admet-505	366	29	bound	bind	VERB
admet-505	366	30	-	-	PUNCT
admet-505	366	31	micelle	micelle	NOUN
admet-505	366	32	fraction	fraction	NOUN
admet-505	366	33	,	,	PUNCT
admet-505	366	34	fbm	fbm	NOUN
admet-505	366	35	=	=	PUNCT
admet-505	367	1	[	[	X
admet-505	367	2	bnmic	bnmic	ADJ
admet-505	367	3	12]/[mic]tot	12]/[mic]tot	NUM
admet-505	367	4	=	=	SYM
admet-505	367	5	kn	kn	PROPN
admet-505	367	6	s0	s0	PROPN
admet-505	367	7	n	n	PROPN
admet-505	367	8	/(1	/(1	PUNCT
admet-505	368	1	+	+	CCONJ
admet-505	368	2	kn	kn	PROPN
admet-505	368	3	s0	s0	PROPN
admet-505	368	4	n	n	PROPN
admet-505	368	5	)	)	PUNCT
admet-505	368	6	,	,	PUNCT
admet-505	368	7	which	which	PRON
admet-505	368	8	can	can	AUX
admet-505	368	9	take	take	VERB
admet-505	368	10	on	on	ADP
admet-505	368	11	values	value	NOUN
admet-505	368	12	0	0	NUM
admet-505	368	13	-	-	SYM
admet-505	368	14	1	1	NUM
admet-505	368	15	.	.	PUNCT
admet-505	368	16	from	from	ADP
admet-505	368	17	this	this	PRON
admet-505	368	18	,	,	PUNCT
admet-505	368	19	the	the	DET
admet-505	368	20	average	average	ADJ
admet-505	368	21	number	number	NOUN
admet-505	368	22	of	of	ADP
admet-505	368	23	bound	bind	VERB
admet-505	368	24	drugs	drug	NOUN
admet-505	368	25	per	per	ADP
admet-505	368	26	micelle	micelle	NOUN
admet-505	368	27	is	be	AUX
admet-505	368	28	nd	nd	ADP
admet-505	368	29	=	=	NOUN
admet-505	368	30	n	n	DET
admet-505	368	31	fbm	fbm	NOUN
admet-505	368	32	.	.	PUNCT
admet-505	369	1	eq	eq	ADP
admet-505	369	2	.	.	PUNCT
admet-505	370	1	(	(	PUNCT
admet-505	370	2	12	12	NUM
admet-505	370	3	)	)	PUNCT
admet-505	370	4	indicates	indicate	VERB
admet-505	370	5	that	that	SCONJ
admet-505	370	6	k	k	PROPN
admet-505	370	7	is	be	AUX
admet-505	370	8	a	a	DET
admet-505	370	9	function	function	NOUN
admet-505	370	10	of	of	ADP
admet-505	370	11	both	both	CCONJ
admet-505	370	12	the	the	DET
admet-505	370	13	intrinsic	intrinsic	ADJ
admet-505	370	14	solubility	solubility	NOUN
admet-505	370	15	,	,	PUNCT
admet-505	370	16	s0	s0	PROPN
admet-505	370	17	,	,	PUNCT
admet-505	370	18	and	and	CCONJ
admet-505	370	19	the	the	DET
admet-505	370	20	drug	drug	NOUN
admet-505	370	21	-	-	PUNCT
admet-505	370	22	micelle	micelle	NOUN
admet-505	370	23	binding	bind	VERB
admet-505	370	24	constant	constant	ADJ
admet-505	370	25	,	,	PUNCT
admet-505	370	26	kn	kn	PROPN
admet-505	370	27	.	.	PUNCT
admet-505	371	1	if	if	SCONJ
admet-505	371	2	both	both	PRON
admet-505	371	3	k	k	PROPN
admet-505	371	4	and	and	CCONJ
admet-505	371	5	s0	s0	PROPN
admet-505	371	6	are	be	AUX
admet-505	371	7	known	know	VERB
admet-505	371	8	,	,	PUNCT
admet-505	371	9	or	or	CCONJ
admet-505	371	10	can	can	AUX
admet-505	371	11	be	be	AUX
admet-505	371	12	in	in	ADP
admet-505	371	13	silico	silico	NOUN
admet-505	371	14	estimated	estimate	VERB
admet-505	371	15	,	,	PUNCT
admet-505	371	16	then	then	ADV
admet-505	371	17	one	one	PRON
admet-505	371	18	can	can	AUX
admet-505	371	19	calculate	calculate	VERB
admet-505	371	20	from	from	ADP
admet-505	371	21	eq	eq	PROPN
admet-505	371	22	.	.	PUNCT
admet-505	372	1	(	(	PUNCT
admet-505	372	2	12	12	NUM
admet-505	372	3	)	)	PUNCT
admet-505	372	4	the	the	DET
admet-505	372	5	drug	drug	NOUN
admet-505	372	6	-	-	PUNCT
admet-505	372	7	micelle	micelle	NOUN
admet-505	372	8	binding	bind	VERB
admet-505	372	9	constant	constant	ADJ
admet-505	372	10	as	as	ADP
admet-505	372	11	:	:	PUNCT
admet-505	372	12	log	log	NOUN
admet-505	372	13	kn	kn	PROPN
admet-505	372	14	=	=	PUNCT
admet-505	372	15	log	log	PROPN
admet-505	372	16	k	k	PROPN
admet-505	372	17	n	n	CCONJ
admet-505	372	18	log	log	VERB
admet-505	372	19	s0	s0	PROPN
admet-505	372	20	+	+	CCONJ
admet-505	372	21	log	log	NOUN
admet-505	372	22	nagg	nagg	NOUN
admet-505	372	23	log	log	NOUN
admet-505	372	24	(	(	PUNCT
admet-505	372	25	n	n	X
admet-505	372	26	–	–	PUNCT
admet-505	372	27	k	k	PROPN
admet-505	372	28	nagg	nagg	PRON
admet-505	372	29	)	)	PUNCT
admet-505	372	30	.	.	PUNCT
admet-505	373	1	(	(	PUNCT
admet-505	373	2	13	13	NUM
admet-505	373	3	)	)	PUNCT
admet-505	373	4	a	a	DET
admet-505	373	5	single	single	ADJ
admet-505	373	6	value	value	NOUN
admet-505	373	7	of	of	ADP
admet-505	373	8	n	n	PROPN
admet-505	373	9	implies	imply	VERB
admet-505	373	10	a	a	DET
admet-505	373	11	perfectly	perfectly	ADV
admet-505	373	12	monodisperse	monodisperse	ADJ
admet-505	373	13	distribution	distribution	NOUN
admet-505	373	14	of	of	ADP
admet-505	373	15	micelle	micelle	NOUN
admet-505	373	16	size	size	NOUN
admet-505	373	17	.	.	PUNCT
admet-505	374	1	a	a	DET
admet-505	374	2	narrow	narrow	ADJ
admet-505	374	3	range	range	NOUN
admet-505	374	4	of	of	ADP
admet-505	374	5	n	n	PRON
admet-505	374	6	values	value	NOUN
admet-505	374	7	is	be	AUX
admet-505	374	8	more	more	ADV
admet-505	374	9	likely	likely	ADJ
admet-505	374	10	to	to	PART
admet-505	374	11	reflect	reflect	VERB
admet-505	374	12	the	the	DET
admet-505	374	13	actual	actual	ADJ
admet-505	374	14	equilibrium	equilibrium	NOUN
admet-505	374	15	process	process	NOUN
admet-505	374	16	,	,	PUNCT
admet-505	374	17	but	but	CCONJ
admet-505	374	18	the	the	DET
admet-505	374	19	calculation	calculation	NOUN
admet-505	374	20	model	model	NOUN
admet-505	374	21	considered	consider	VERB
admet-505	374	22	here	here	ADV
admet-505	374	23	assumed	assume	VERB
admet-505	374	24	a	a	DET
admet-505	374	25	single	single	ADJ
admet-505	374	26	value	value	NOUN
admet-505	374	27	.	.	PUNCT
admet-505	375	1	if	if	SCONJ
admet-505	375	2	the	the	DET
admet-505	375	3	total	total	ADJ
admet-505	375	4	solubility	solubility	NOUN
admet-505	375	5	,	,	PUNCT
admet-505	375	6	eq	eq	NOUN
admet-505	375	7	.	.	PUNCT
admet-505	375	8	(	(	PUNCT
admet-505	375	9	11	11	NUM
admet-505	375	10	)	)	PUNCT
admet-505	375	11	,	,	PUNCT
admet-505	375	12	is	be	AUX
admet-505	375	13	the	the	DET
admet-505	375	14	only	only	ADJ
admet-505	375	15	dependent	dependent	ADJ
admet-505	375	16	variable	variable	NOUN
admet-505	375	17	in	in	ADP
admet-505	375	18	the	the	DET
admet-505	375	19	design	design	NOUN
admet-505	375	20	equation	equation	NOUN
admet-505	375	21	to	to	PART
admet-505	375	22	determine	determine	VERB
admet-505	375	23	kn	kn	PROPN
admet-505	375	24	by	by	ADP
admet-505	375	25	regression	regression	NOUN
admet-505	375	26	analysis	analysis	NOUN
admet-505	375	27	,	,	PUNCT
admet-505	375	28	then	then	ADV
admet-505	375	29	any	any	DET
admet-505	375	30	practical	practical	ADJ
admet-505	375	31	value	value	NOUN
admet-505	375	32	of	of	ADP
admet-505	375	33	n	n	PROPN
admet-505	375	34	>	>	X
admet-505	375	35	k	k	PROPN
admet-505	375	36	nagg	nagg	PROPN
admet-505	375	37	would	would	AUX
admet-505	375	38	satisfy	satisfy	VERB
admet-505	375	39	the	the	DET
admet-505	375	40	fitting	fitting	ADJ
admet-505	375	41	process	process	NOUN
admet-505	375	42	.	.	PUNCT
admet-505	376	1	in	in	ADP
admet-505	376	2	the	the	DET
admet-505	376	3	discussion	discussion	NOUN
admet-505	376	4	here	here	ADV
admet-505	376	5	,	,	PUNCT
admet-505	376	6	n	n	PRON
admet-505	376	7	is	be	AUX
admet-505	376	8	taken	take	VERB
admet-505	376	9	to	to	PART
admet-505	376	10	be	be	AUX
admet-505	376	11	k	k	PROPN
admet-505	376	12	nagg	nagg	PROPN
admet-505	376	13	rounded	round	VERB
admet-505	376	14	up	up	ADP
admet-505	376	15	to	to	ADP
admet-505	376	16	the	the	DET
admet-505	376	17	next	next	ADJ
admet-505	376	18	integral	integral	ADJ
admet-505	376	19	value	value	NOUN
admet-505	376	20	(	(	PUNCT
admet-505	376	21	using	use	VERB
admet-505	376	22	the	the	DET
admet-505	376	23	modulo	modulo	NOUN
admet-505	376	24	operator	operator	NOUN
admet-505	376	25	)	)	PUNCT
admet-505	376	26	,	,	PUNCT
admet-505	376	27	i.e.	i.e.	X
admet-505	376	28	,	,	PUNCT
admet-505	376	29	n	n	NOUN
admet-505	376	30	=	=	SYM
admet-505	376	31	1	1	NUM
admet-505	376	32	+	+	CCONJ
admet-505	376	33	k	k	PROPN
admet-505	376	34	nagg	nagg	PRON
admet-505	376	35	–	–	PUNCT
admet-505	376	36	mod(k	mod(k	PROPN
admet-505	376	37	nagg	nagg	NOUN
admet-505	376	38	,	,	PUNCT
admet-505	376	39	1	1	NUM
admet-505	376	40	)	)	PUNCT
admet-505	376	41	.	.	PUNCT
admet-505	377	1	(	(	PUNCT
admet-505	377	2	14	14	X
admet-505	377	3	)	)	PUNCT
admet-505	377	4	note	note	VERB
admet-505	377	5	that	that	SCONJ
admet-505	377	6	eq	eq	X
admet-505	377	7	.	.	PUNCT
admet-505	378	1	(	(	PUNCT
admet-505	378	2	13	13	NUM
admet-505	378	3	)	)	PUNCT
admet-505	378	4	is	be	AUX
admet-505	378	5	only	only	ADV
admet-505	378	6	valid	valid	ADJ
admet-505	378	7	for	for	ADP
admet-505	378	8	solubilization	solubilization	NOUN
admet-505	378	9	of	of	ADP
admet-505	378	10	uncharged	uncharged	ADJ
admet-505	378	11	drugs	drug	NOUN
admet-505	378	12	(	(	PUNCT
admet-505	378	13	e.g.	e.g.	ADV
admet-505	378	14	,	,	PUNCT
admet-505	378	15	eq	eq	NOUN
admet-505	378	16	.	.	PROPN
admet-505	378	17	3	3	NUM
admet-505	378	18	)	)	PUNCT
admet-505	378	19	,	,	PUNCT
admet-505	378	20	where	where	SCONJ
admet-505	378	21	the	the	DET
admet-505	378	22	only	only	ADJ
admet-505	378	23	precipitate	precipitate	NOUN
admet-505	378	24	in	in	ADP
admet-505	378	25	the	the	DET
admet-505	378	26	suspension	suspension	NOUN
admet-505	378	27	is	be	AUX
admet-505	378	28	the	the	DET
admet-505	378	29	nonionized	nonionize	VERB
admet-505	378	30	drug	drug	NOUN
admet-505	378	31	.	.	PUNCT
admet-505	379	1	a	a	DET
admet-505	379	2	different	different	ADJ
admet-505	379	3	explicit	explicit	ADJ
admet-505	379	4	equation	equation	NOUN
admet-505	379	5	can	can	AUX
admet-505	379	6	be	be	AUX
admet-505	379	7	derived	derive	VERB
admet-505	379	8	to	to	PART
admet-505	379	9	take	take	VERB
admet-505	379	10	into	into	ADP
admet-505	379	11	account	account	NOUN
admet-505	379	12	charged	charge	VERB
admet-505	379	13	-	-	PUNCT
admet-505	379	14	drug	drug	NOUN
admet-505	379	15	precipitation	precipitation	NOUN
admet-505	379	16	and	and	CCONJ
admet-505	379	17	sds	sds	NOUN
admet-505	379	18	solubilization	solubilization	NOUN
admet-505	379	19	of	of	ADP
admet-505	379	20	charged	charge	VERB
admet-505	379	21	drug	drug	NOUN
admet-505	379	22	(	(	PUNCT
admet-505	379	23	not	not	PART
admet-505	379	24	done	do	VERB
admet-505	379	25	here	here	ADV
admet-505	379	26	)	)	PUNCT
admet-505	379	27	.	.	PUNCT
admet-505	380	1	equilibrium	equilibrium	NOUN
admet-505	380	2	model	model	NOUN
admet-505	380	3	and	and	CCONJ
admet-505	380	4	the	the	DET
admet-505	380	5	computer	computer	NOUN
admet-505	380	6	program	program	NOUN
admet-505	380	7	the	the	DET
admet-505	380	8	general	general	ADJ
admet-505	380	9	computer	computer	NOUN
admet-505	380	10	program	program	NOUN
admet-505	380	11	pdisol	pdisol	NOUN
admet-505	380	12	-	-	PUNCT
admet-505	380	13	x	x	SYM
admet-505	380	14	(	(	PUNCT
admet-505	380	15	in	in	ADP
admet-505	380	16	-	-	PUNCT
admet-505	380	17	adme	adme	NOUN
admet-505	380	18	research	research	NOUN
admet-505	380	19	)	)	PUNCT
admet-505	380	20	was	be	AUX
admet-505	380	21	used	use	VERB
admet-505	380	22	to	to	PART
admet-505	380	23	solve	solve	VERB
admet-505	380	24	mass	mass	ADJ
admet-505	380	25	balance	balance	NOUN
admet-505	380	26	expressions	expression	NOUN
admet-505	380	27	,	,	PUNCT
admet-505	380	28	such	such	ADJ
admet-505	380	29	as	as	ADP
admet-505	380	30	eqs	eqs	PROPN
admet-505	380	31	.	.	PUNCT
admet-505	381	1	(	(	PUNCT
admet-505	381	2	8)-(10	8)-(10	NUM
admet-505	381	3	)	)	PUNCT
admet-505	381	4	,	,	PUNCT
admet-505	381	5	for	for	ADP
admet-505	381	6	all	all	PRON
admet-505	381	7	of	of	ADP
admet-505	381	8	the	the	DET
admet-505	381	9	reactant	reactant	NOUN
admet-505	381	10	concentrations	concentration	NOUN
admet-505	381	11	in	in	ADP
admet-505	381	12	both	both	CCONJ
admet-505	381	13	aqueous	aqueous	ADJ
admet-505	381	14	and	and	CCONJ
admet-505	381	15	the	the	DET
admet-505	381	16	aqueousmicellar	aqueousmicellar	ADV
admet-505	381	17	-	-	PUNCT
admet-505	381	18	solid	solid	ADJ
admet-505	381	19	media	medium	NOUN
admet-505	381	20	.	.	PUNCT
admet-505	382	1	the	the	DET
admet-505	382	2	program	program	NOUN
admet-505	382	3	can	can	AUX
admet-505	382	4	analyze	analyze	VERB
admet-505	382	5	single	single	ADJ
admet-505	382	6	-	-	PUNCT
admet-505	382	7	api	api	NOUN
admet-505	382	8	solubility	solubility	NOUN
admet-505	382	9	data	datum	NOUN
admet-505	382	10	[	[	X
admet-505	382	11	21	21	NUM
admet-505	382	12	-	-	SYM
admet-505	382	13	25	25	NUM
admet-505	382	14	]	]	PUNCT
admet-505	382	15	or	or	CCONJ
admet-505	382	16	cocrystal	cocrystal	ADJ
admet-505	382	17	dualadmet	dualadmet	PROPN
admet-505	382	18	&	&	CCONJ
admet-505	382	19	dmpk	dmpk	PROPN
admet-505	382	20	6(2	6(2	NUM
admet-505	382	21	)	)	PUNCT
admet-505	382	22	(	(	PUNCT
admet-505	382	23	2018	2018	NUM
admet-505	382	24	)	)	PUNCT
admet-505	382	25	105	105	NUM
admet-505	382	26	-	-	SYM
admet-505	382	27	139	139	NUM
admet-505	382	28	cocrystal	cocrystal	ADJ
admet-505	382	29	solubility	solubility	NOUN
admet-505	382	30	-	-	PUNCT
admet-505	382	31	ph	ph	VERB
admet-505	382	32	,	,	PUNCT
admet-505	382	33	drug	drug	NOUN
admet-505	382	34	solubilization	solubilization	NOUN
admet-505	382	35	capacity	capacity	NOUN
admet-505	382	36	of	of	ADP
admet-505	382	37	sds	sds	PROPN
admet-505	382	38	,	,	PUNCT
admet-505	382	39	mass	mass	ADJ
admet-505	382	40	action	action	NOUN
admet-505	382	41	model	model	NOUN
admet-505	382	42	doi	doi	PROPN
admet-505	382	43	:	:	PUNCT
admet-505	382	44	10.5599	10.5599	NUM
admet-505	382	45	/	/	SYM
admet-505	382	46	admet.505	admet.505	PROPN
admet-505	382	47	111	111	NUM
admet-505	382	48	concentration	concentration	NOUN
admet-505	382	49	eutectic	eutectic	ADJ
admet-505	382	50	data	datum	NOUN
admet-505	382	51	,	,	PUNCT
admet-505	382	52	as	as	ADP
admet-505	382	53	a	a	DET
admet-505	382	54	function	function	NOUN
admet-505	382	55	of	of	ADP
admet-505	382	56	ph	ph	NOUN
admet-505	382	57	[	[	X
admet-505	382	58	16	16	NUM
admet-505	382	59	,	,	PUNCT
admet-505	382	60	17	17	NUM
admet-505	382	61	]	]	PUNCT
admet-505	382	62	.	.	PUNCT
admet-505	383	1	salt	salt	NOUN
admet-505	383	2	solubility	solubility	NOUN
admet-505	383	3	products	product	NOUN
admet-505	383	4	(	(	PUNCT
admet-505	383	5	including	include	VERB
admet-505	383	6	drug	drug	NOUN
admet-505	383	7	-	-	PUNCT
admet-505	383	8	sds	sds	NOUN
admet-505	383	9	salt	salt	NOUN
admet-505	383	10	formation	formation	NOUN
admet-505	383	11	)	)	PUNCT
admet-505	383	12	,	,	PUNCT
admet-505	383	13	complexation	complexation	NOUN
admet-505	383	14	reactions	reaction	NOUN
admet-505	383	15	(	(	PUNCT
admet-505	383	16	e.g.	e.g.	ADV
admet-505	383	17	,	,	PUNCT
admet-505	383	18	drug	drug	NOUN
admet-505	383	19	-	-	PUNCT
admet-505	383	20	micelle	micelle	NOUN
admet-505	383	21	binding	binding	NOUN
admet-505	383	22	)	)	PUNCT
admet-505	383	23	,	,	PUNCT
admet-505	383	24	and	and	CCONJ
admet-505	383	25	aggregation	aggregation	NOUN
admet-505	383	26	formations	formation	NOUN
admet-505	383	27	(	(	PUNCT
admet-505	383	28	drug	drug	NOUN
admet-505	383	29	or	or	CCONJ
admet-505	383	30	surfactant	surfactant	NOUN
admet-505	383	31	)	)	PUNCT
admet-505	383	32	can	can	AUX
admet-505	383	33	be	be	AUX
admet-505	383	34	considered	consider	VERB
admet-505	383	35	.	.	PUNCT
admet-505	384	1	algorithms	algorithm	NOUN
admet-505	384	2	for	for	ADP
admet-505	384	3	temperature	temperature	NOUN
admet-505	384	4	[	[	X
admet-505	384	5	26	26	NUM
admet-505	384	6	]	]	PUNCT
admet-505	384	7	and	and	CCONJ
admet-505	384	8	automatic	automatic	ADJ
admet-505	384	9	ionic	ionic	ADJ
admet-505	384	10	strength	strength	NOUN
admet-505	384	11	[	[	X
admet-505	384	12	27	27	NUM
admet-505	384	13	]	]	PUNCT
admet-505	384	14	compensations	compensation	NOUN
admet-505	384	15	have	have	AUX
admet-505	384	16	been	be	AUX
admet-505	384	17	incorporated	incorporate	VERB
admet-505	384	18	.	.	PUNCT
admet-505	385	1	during	during	ADP
admet-505	385	2	calculation	calculation	NOUN
admet-505	385	3	,	,	PUNCT
admet-505	385	4	the	the	DET
admet-505	385	5	equilibrium	equilibrium	NOUN
admet-505	385	6	constants	constant	NOUN
admet-505	385	7	are	be	AUX
admet-505	385	8	adjusted	adjust	VERB
admet-505	385	9	for	for	ADP
admet-505	385	10	activity	activity	NOUN
admet-505	385	11	effects	effect	NOUN
admet-505	385	12	,	,	PUNCT
admet-505	385	13	based	base	VERB
admet-505	385	14	on	on	ADP
admet-505	385	15	the	the	DET
admet-505	385	16	stokes	stokes	PROPN
admet-505	385	17	-	-	PUNCT
admet-505	385	18	robinson	robinson	PROPN
admet-505	385	19	hydration	hydration	NOUN
admet-505	385	20	theory	theory	NOUN
admet-505	385	21	[	[	X
admet-505	385	22	21	21	NUM
admet-505	385	23	]	]	PUNCT
admet-505	385	24	.	.	PUNCT
admet-505	386	1	the	the	DET
admet-505	386	2	overall	overall	ADJ
admet-505	386	3	generalized	generalized	ADJ
admet-505	386	4	approach	approach	NOUN
admet-505	386	5	allows	allow	VERB
admet-505	386	6	for	for	ADP
admet-505	386	7	quick	quick	ADJ
admet-505	386	8	testing	testing	NOUN
admet-505	386	9	of	of	ADP
admet-505	386	10	many	many	ADJ
admet-505	386	11	possible	possible	ADJ
admet-505	386	12	equilibrium	equilibrium	NOUN
admet-505	386	13	models	model	NOUN
admet-505	386	14	.	.	PUNCT
admet-505	387	1	the	the	DET
admet-505	387	2	details	detail	NOUN
admet-505	387	3	of	of	ADP
admet-505	387	4	how	how	SCONJ
admet-505	387	5	the	the	DET
admet-505	387	6	solubility	solubility	NOUN
admet-505	387	7	products	product	NOUN
admet-505	387	8	are	be	AUX
admet-505	387	9	determined	determine	VERB
admet-505	387	10	by	by	ADP
admet-505	387	11	regression	regression	NOUN
admet-505	387	12	analysis	analysis	NOUN
admet-505	387	13	of	of	ADP
admet-505	387	14	eutectic	eutectic	ADJ
admet-505	387	15	data	datum	NOUN
admet-505	387	16	and	and	CCONJ
admet-505	387	17	how	how	SCONJ
admet-505	387	18	simulation	simulation	NOUN
admet-505	387	19	calculations	calculation	NOUN
admet-505	387	20	are	be	AUX
admet-505	387	21	performed	perform	VERB
admet-505	387	22	using	use	VERB
admet-505	387	23	the	the	DET
admet-505	387	24	ksp	ksp	PROPN
admet-505	387	25	and	and	CCONJ
admet-505	387	26	other	other	ADJ
admet-505	387	27	equilibrium	equilibrium	NOUN
admet-505	387	28	constants	constant	NOUN
admet-505	387	29	are	be	AUX
admet-505	387	30	not	not	PART
admet-505	387	31	presented	present	VERB
admet-505	387	32	here	here	ADV
admet-505	387	33	,	,	PUNCT
admet-505	387	34	since	since	SCONJ
admet-505	387	35	that	that	DET
admet-505	387	36	procedure	procedure	NOUN
admet-505	387	37	already	already	ADV
admet-505	387	38	has	have	AUX
admet-505	387	39	been	be	AUX
admet-505	387	40	described	describe	VERB
admet-505	387	41	in	in	ADP
admet-505	387	42	substantial	substantial	ADJ
admet-505	387	43	depth	depth	NOUN
admet-505	387	44	elsewhere	elsewhere	ADV
admet-505	387	45	[	[	X
admet-505	387	46	16	16	NUM
admet-505	387	47	,	,	PUNCT
admet-505	387	48	17	17	NUM
admet-505	387	49	]	]	PUNCT
admet-505	387	50	.	.	PUNCT
admet-505	388	1	briefly	briefly	NOUN
admet-505	388	2	,	,	PUNCT
admet-505	388	3	the	the	DET
admet-505	388	4	equilibrium	equilibrium	NOUN
admet-505	388	5	analysis	analysis	NOUN
admet-505	388	6	does	do	AUX
admet-505	388	7	not	not	PART
admet-505	388	8	depend	depend	VERB
admet-505	388	9	on	on	ADP
admet-505	388	10	explicitly	explicitly	ADV
admet-505	388	11	-	-	PUNCT
admet-505	388	12	derived	derive	VERB
admet-505	388	13	extensions	extension	NOUN
admet-505	388	14	of	of	ADP
admet-505	388	15	the	the	DET
admet-505	388	16	henderson	henderson	PROPN
admet-505	388	17	-	-	PUNCT
admet-505	388	18	hasselbalch	hasselbalch	PROPN
admet-505	388	19	solubility	solubility	NOUN
admet-505	388	20	equations	equation	NOUN
admet-505	388	21	,	,	PUNCT
admet-505	388	22	such	such	ADJ
admet-505	388	23	as	as	ADP
admet-505	388	24	eq	eq	ADJ
admet-505	388	25	.	.	PUNCT
admet-505	389	1	(	(	PUNCT
admet-505	389	2	11	11	NUM
admet-505	389	3	)	)	PUNCT
admet-505	389	4	.	.	PUNCT
admet-505	390	1	the	the	DET
admet-505	390	2	computational	computational	ADJ
admet-505	390	3	algorithm	algorithm	NOUN
admet-505	390	4	derives	derive	VERB
admet-505	390	5	its	its	PRON
admet-505	390	6	own	own	ADJ
admet-505	390	7	implicit	implicit	ADJ
admet-505	390	8	equations	equation	NOUN
admet-505	390	9	internally	internally	ADV
admet-505	390	10	in	in	ADP
admet-505	390	11	the	the	DET
admet-505	390	12	context	context	NOUN
admet-505	390	13	of	of	ADP
admet-505	390	14	the	the	DET
admet-505	390	15	mass	mass	ADJ
admet-505	390	16	action	action	NOUN
admet-505	390	17	model	model	NOUN
admet-505	390	18	,	,	PUNCT
admet-505	390	19	given	give	VERB
admet-505	390	20	a	a	DET
admet-505	390	21	set	set	NOUN
admet-505	390	22	of	of	ADP
admet-505	390	23	equilibria	equilibrium	NOUN
admet-505	390	24	(	(	PUNCT
admet-505	390	25	entered	enter	VERB
admet-505	390	26	as	as	SCONJ
admet-505	390	27	text	text	NOUN
admet-505	390	28	arrays	array	VERB
admet-505	390	29	,	,	PUNCT
admet-505	390	30	with	with	ADP
admet-505	390	31	hash	hash	NOUN
admet-505	390	32	tags	tag	NOUN
admet-505	390	33	denoting	denote	VERB
admet-505	390	34	solid	solid	ADJ
admet-505	390	35	phase	phase	NOUN
admet-505	390	36	:	:	PUNCT
admet-505	390	37	e.g.	e.g.	ADV
admet-505	390	38	,	,	PUNCT
admet-505	390	39	eqs	eqs	X
admet-505	390	40	.	.	PROPN
admet-505	391	1	(	(	PUNCT
admet-505	391	2	2)-(4	2)-(4	NUM
admet-505	391	3	)	)	PUNCT
admet-505	391	4	with	with	ADP
admet-505	391	5	n=2	n=2	ADV
admet-505	391	6	,	,	PUNCT
admet-505	391	7	“	"	PUNCT
admet-505	391	8	b+h	b+h	NUM
admet-505	391	9	=	=	SYM
admet-505	391	10	bh	bh	NOUN
admet-505	391	11	”	"	PUNCT
admet-505	391	12	,	,	PUNCT
admet-505	391	13	“	"	PUNCT
admet-505	391	14	2b+mic	2b+mic	ADJ
admet-505	391	15	=	=	SYM
admet-505	391	16	b2mic	b2mic	ADJ
admet-505	391	17	”	"	PUNCT
admet-505	391	18	,	,	PUNCT
admet-505	391	19	and	and	CCONJ
admet-505	391	20	“	"	PUNCT
admet-505	391	21	b	b	X
admet-505	391	22	=	=	SYM
admet-505	391	23	b	b	NOUN
admet-505	391	24	#	#	NOUN
admet-505	391	25	”	"	PUNCT
admet-505	391	26	)	)	PUNCT
admet-505	391	27	and	and	CCONJ
admet-505	391	28	the	the	DET
admet-505	391	29	corresponding	corresponding	ADJ
admet-505	391	30	estimated	estimate	VERB
admet-505	391	31	equilibrium	equilibrium	NOUN
admet-505	391	32	constants	constant	NOUN
admet-505	391	33	.	.	PUNCT
admet-505	392	1	the	the	DET
admet-505	392	2	text	text	NOUN
admet-505	392	3	array	array	NOUN
admet-505	392	4	of	of	ADP
admet-505	392	5	equilibria	equilibrium	NOUN
admet-505	392	6	is	be	AUX
admet-505	392	7	automatically	automatically	ADV
admet-505	392	8	parsed	parse	VERB
admet-505	392	9	to	to	PART
admet-505	392	10	construct	construct	VERB
admet-505	392	11	the	the	DET
admet-505	392	12	appropriate	appropriate	ADJ
admet-505	392	13	mass	mass	NOUN
admet-505	392	14	balance	balance	NOUN
admet-505	392	15	expressions	expression	NOUN
admet-505	392	16	in	in	ADP
admet-505	392	17	terms	term	NOUN
admet-505	392	18	of	of	ADP
admet-505	392	19	reactant	reactant	NOUN
admet-505	392	20	concentrations	concentration	NOUN
admet-505	392	21	and	and	CCONJ
admet-505	392	22	equilibrium	equilibrium	NOUN
admet-505	392	23	constants	constant	NOUN
admet-505	392	24	.	.	PUNCT
admet-505	393	1	the	the	DET
admet-505	393	2	weighted	weighted	ADJ
admet-505	393	3	nonlinear	nonlinear	ADJ
admet-505	393	4	least	least	ADJ
admet-505	393	5	-	-	PUNCT
admet-505	393	6	squares	square	NOUN
admet-505	393	7	calculation	calculation	NOUN
admet-505	393	8	considers	consider	VERB
admet-505	393	9	the	the	DET
admet-505	393	10	contribution	contribution	NOUN
admet-505	393	11	from	from	ADP
admet-505	393	12	multiple	multiple	ADJ
admet-505	393	13	substances	substance	NOUN
admet-505	393	14	–	–	PUNCT
admet-505	393	15	not	not	PART
admet-505	393	16	only	only	ADV
admet-505	393	17	the	the	DET
admet-505	393	18	api	api	NOUN
admet-505	393	19	,	,	PUNCT
admet-505	393	20	micelle	micelle	NOUN
admet-505	393	21	,	,	PUNCT
admet-505	393	22	and	and	CCONJ
admet-505	393	23	coformer	coformer	NOUN
admet-505	393	24	,	,	PUNCT
admet-505	393	25	but	but	CCONJ
admet-505	393	26	also	also	ADV
admet-505	393	27	all	all	PRON
admet-505	393	28	of	of	ADP
admet-505	393	29	the	the	DET
admet-505	393	30	reactants	reactant	NOUN
admet-505	393	31	in	in	ADP
admet-505	393	32	solution	solution	NOUN
admet-505	393	33	,	,	PUNCT
admet-505	393	34	including	include	VERB
admet-505	393	35	buffers	buffer	NOUN
admet-505	393	36	and	and	CCONJ
admet-505	393	37	background	background	NOUN
admet-505	393	38	salts	salt	NOUN
admet-505	393	39	used	use	VERB
admet-505	393	40	to	to	PART
admet-505	393	41	control	control	VERB
admet-505	393	42	the	the	DET
admet-505	393	43	ionic	ionic	ADJ
admet-505	393	44	strength	strength	NOUN
admet-505	393	45	.	.	PUNCT
admet-505	394	1	currently	currently	ADV
admet-505	394	2	,	,	PUNCT
admet-505	394	3	up	up	ADP
admet-505	394	4	to	to	PART
admet-505	394	5	three	three	NUM
admet-505	394	6	solid	solid	ADJ
admet-505	394	7	phases	phase	NOUN
admet-505	394	8	may	may	AUX
admet-505	394	9	be	be	AUX
admet-505	394	10	addressed	address	VERB
admet-505	394	11	in	in	ADP
admet-505	394	12	the	the	DET
admet-505	394	13	same	same	ADJ
admet-505	394	14	calculation	calculation	NOUN
admet-505	394	15	(	(	PUNCT
admet-505	394	16	provided	provide	VERB
admet-505	394	17	they	they	PRON
admet-505	394	18	do	do	AUX
admet-505	394	19	not	not	PART
admet-505	394	20	violate	violate	VERB
admet-505	394	21	the	the	DET
admet-505	394	22	gibbs	gibbs	PROPN
admet-505	394	23	’	'	PUNCT
admet-505	394	24	phase	phase	NOUN
admet-505	394	25	rule	rule	NOUN
admet-505	394	26	constraint	constraint	NOUN
admet-505	394	27	,	,	PUNCT
admet-505	394	28	for	for	ADP
admet-505	394	29	which	which	PRON
admet-505	394	30	the	the	DET
admet-505	394	31	computer	computer	NOUN
admet-505	394	32	program	program	NOUN
admet-505	394	33	tests	test	NOUN
admet-505	394	34	)	)	PUNCT
admet-505	394	35	.	.	PUNCT
admet-505	395	1	in	in	ADP
admet-505	395	2	cocrystal	cocrystal	ADJ
admet-505	395	3	applications	application	NOUN
admet-505	395	4	,	,	PUNCT
admet-505	395	5	the	the	DET
admet-505	395	6	procedure	procedure	NOUN
admet-505	395	7	treats	treat	VERB
admet-505	395	8	the	the	DET
admet-505	395	9	measured	measured	ADJ
admet-505	395	10	total	total	ADJ
admet-505	395	11	aqueous	aqueous	ADJ
admet-505	395	12	api	api	NOUN
admet-505	395	13	and	and	CCONJ
admet-505	395	14	coformer	coformer	PROPN
admet-505	395	15	equilibrium	equilibrium	NOUN
admet-505	395	16	concentrations	concentration	NOUN
admet-505	395	17	,	,	PUNCT
admet-505	395	18	[	[	X
admet-505	395	19	api]tot	api]tot	NOUN
admet-505	395	20	and	and	CCONJ
admet-505	395	21	[	[	X
admet-505	395	22	cof]tot	cof]tot	X
admet-505	395	23	,	,	PUNCT
admet-505	395	24	as	as	ADP
admet-505	395	25	dependent	dependent	ADJ
admet-505	395	26	variables	variable	NOUN
admet-505	395	27	(	(	PUNCT
admet-505	395	28	cf	cf	NOUN
admet-505	395	29	.	.	NOUN
admet-505	395	30	,	,	PUNCT
admet-505	395	31	appendix	appendix	NOUN
admet-505	395	32	)	)	PUNCT
admet-505	395	33	.	.	PUNCT
admet-505	396	1	the	the	DET
admet-505	396	2	surfactant	surfactant	ADJ
admet-505	396	3	concentration	concentration	NOUN
admet-505	396	4	,	,	PUNCT
admet-505	396	5	reactant	reactant	NOUN
admet-505	396	6	weights	weight	NOUN
admet-505	396	7	,	,	PUNCT
admet-505	396	8	reagent	reagent	ADJ
admet-505	396	9	volumes	volume	NOUN
admet-505	396	10	,	,	PUNCT
admet-505	396	11	and	and	CCONJ
admet-505	396	12	ph	ph	NOUN
admet-505	396	13	are	be	AUX
admet-505	396	14	treated	treat	VERB
admet-505	396	15	as	as	ADP
admet-505	396	16	independent	independent	ADJ
admet-505	396	17	variables	variable	NOUN
admet-505	396	18	,	,	PUNCT
admet-505	396	19	whereas	whereas	SCONJ
admet-505	396	20	the	the	DET
admet-505	396	21	equilibrium	equilibrium	NOUN
admet-505	396	22	constants	constant	NOUN
admet-505	396	23	are	be	AUX
admet-505	396	24	the	the	DET
admet-505	396	25	potentially	potentially	ADV
admet-505	396	26	refinable	refinable	ADJ
admet-505	396	27	parameters	parameter	NOUN
admet-505	396	28	.	.	PUNCT
admet-505	397	1	data	datum	NOUN
admet-505	397	2	sources	source	NOUN
admet-505	397	3	molar	molar	ADJ
admet-505	397	4	solubilization	solubilization	NOUN
admet-505	397	5	capacity	capacity	NOUN
admet-505	397	6	,	,	PUNCT
admet-505	397	7	k	k	PROPN
admet-505	397	8	the	the	DET
admet-505	397	9	101	101	NUM
admet-505	397	10	k	k	PROPN
admet-505	397	11	values	value	NOUN
admet-505	397	12	used	use	VERB
admet-505	397	13	in	in	ADP
admet-505	397	14	this	this	DET
admet-505	397	15	study	study	NOUN
admet-505	397	16	were	be	AUX
admet-505	397	17	gathered	gather	VERB
admet-505	397	18	from	from	ADP
admet-505	397	19	published	publish	VERB
admet-505	397	20	sources	source	NOUN
admet-505	397	21	[	[	X
admet-505	397	22	28	28	NUM
admet-505	397	23	-	-	SYM
admet-505	397	24	53	53	NUM
admet-505	397	25	]	]	PUNCT
admet-505	397	26	,	,	PUNCT
admet-505	397	27	and	and	CCONJ
admet-505	397	28	are	be	AUX
admet-505	397	29	listed	list	VERB
admet-505	397	30	in	in	ADP
admet-505	397	31	table	table	NOUN
admet-505	397	32	1	1	NUM
admet-505	397	33	.	.	PUNCT
admet-505	398	1	in	in	ADP
admet-505	398	2	most	most	ADJ
admet-505	398	3	of	of	ADP
admet-505	398	4	the	the	DET
admet-505	398	5	studies	study	NOUN
admet-505	398	6	,	,	PUNCT
admet-505	398	7	multi	multi	ADJ
admet-505	398	8	-	-	ADJ
admet-505	398	9	point	point	ADJ
admet-505	398	10	aqueous	aqueous	ADJ
admet-505	398	11	-	-	PUNCT
admet-505	398	12	micellar	micellar	NOUN
admet-505	398	13	-	-	PUNCT
admet-505	398	14	solid	solid	ADJ
admet-505	398	15	solubility	solubility	NOUN
admet-505	398	16	-	-	PUNCT
admet-505	398	17	sds	sds	PROPN
admet-505	398	18	data	datum	NOUN
admet-505	398	19	were	be	AUX
admet-505	398	20	displayed	display	VERB
admet-505	398	21	solely	solely	ADV
admet-505	398	22	in	in	ADP
admet-505	398	23	plots	plot	NOUN
admet-505	398	24	.	.	PUNCT
admet-505	399	1	these	these	DET
admet-505	399	2	plots	plot	NOUN
admet-505	399	3	were	be	AUX
admet-505	399	4	digitized	digitize	VERB
admet-505	399	5	here	here	ADV
admet-505	399	6	using	use	VERB
admet-505	399	7	webplotdigitizer	webplotdigitizer	NOUN
admet-505	399	8	v.3.5	v.3.5	NOUN
admet-505	399	9	(	(	PUNCT
admet-505	399	10	https://automeris.io/webplotdigitizer/	https://automeris.io/webplotdigitizer/	NUM
admet-505	399	11	)	)	PUNCT
admet-505	399	12	,	,	PUNCT
admet-505	399	13	from	from	ADP
admet-505	399	14	which	which	PRON
admet-505	399	15	the	the	DET
admet-505	399	16	k	k	PROPN
admet-505	399	17	values	value	NOUN
admet-505	399	18	were	be	AUX
admet-505	399	19	re	re	VERB
admet-505	399	20	-	-	VERB
admet-505	399	21	determined	determined	ADJ
admet-505	399	22	,	,	PUNCT
admet-505	399	23	not	not	PART
admet-505	399	24	only	only	ADV
admet-505	399	25	to	to	PART
admet-505	399	26	corroborate	corroborate	VERB
admet-505	399	27	the	the	DET
admet-505	399	28	published	publish	VERB
admet-505	399	29	k	k	PROPN
admet-505	399	30	values	value	NOUN
admet-505	399	31	,	,	PUNCT
admet-505	399	32	but	but	CCONJ
admet-505	399	33	also	also	ADV
admet-505	399	34	to	to	PART
admet-505	399	35	determine	determine	VERB
admet-505	399	36	the	the	DET
admet-505	399	37	extent	extent	NOUN
admet-505	399	38	of	of	ADP
admet-505	399	39	nonlinearity	nonlinearity	NOUN
admet-505	399	40	in	in	ADP
admet-505	399	41	the	the	DET
admet-505	399	42	[	[	X
admet-505	399	43	sds	sds	X
admet-505	399	44	]	]	PUNCT
admet-505	399	45	>	>	X
admet-505	399	46	cmc	cmc	PROPN
admet-505	399	47	data	data	PROPN
admet-505	399	48	.	.	PUNCT
admet-505	400	1	in	in	ADP
admet-505	400	2	several	several	ADJ
admet-505	400	3	cases	case	NOUN
admet-505	400	4	with	with	ADP
admet-505	400	5	high	high	ADJ
admet-505	400	6	sds	sds	PROPN
admet-505	400	7	concentrations	concentration	NOUN
admet-505	400	8	,	,	PUNCT
admet-505	400	9	the	the	DET
admet-505	400	10	slopes	slope	NOUN
admet-505	400	11	slightly	slightly	ADV
admet-505	400	12	decreased	decrease	VERB
admet-505	400	13	with	with	ADP
admet-505	400	14	increasing	increase	VERB
admet-505	400	15	surfactant	surfactant	ADJ
admet-505	400	16	concentration	concentration	NOUN
admet-505	400	17	.	.	PUNCT
admet-505	401	1	the	the	DET
admet-505	401	2	re	re	NOUN
admet-505	401	3	-	-	VERB
admet-505	401	4	calculated	calculated	ADJ
admet-505	401	5	k	k	PROPN
admet-505	401	6	values	value	NOUN
admet-505	401	7	were	be	AUX
admet-505	401	8	equated	equate	VERB
admet-505	401	9	to	to	ADP
admet-505	401	10	the	the	DET
admet-505	401	11	slopes	slope	NOUN
admet-505	401	12	evaluated	evaluate	VERB
admet-505	401	13	at	at	ADP
admet-505	401	14	the	the	DET
admet-505	401	15	cmc	cmc	NOUN
admet-505	401	16	.	.	PUNCT
admet-505	402	1	not	not	PART
admet-505	402	2	all	all	DET
admet-505	402	3	values	value	NOUN
admet-505	402	4	could	could	AUX
admet-505	402	5	be	be	AUX
admet-505	402	6	re	re	VERB
admet-505	402	7	-	-	VERB
admet-505	402	8	calculated	calculate	VERB
admet-505	402	9	.	.	PUNCT
admet-505	403	1	for	for	ADP
admet-505	403	2	example	example	NOUN
admet-505	403	3	,	,	PUNCT
admet-505	403	4	the	the	DET
admet-505	403	5	calculated	calculated	ADJ
admet-505	403	6	k	k	PROPN
admet-505	403	7	values	value	NOUN
admet-505	403	8	of	of	ADP
admet-505	403	9	iminophenazines	iminophenazine	NOUN
admet-505	403	10	(	(	PUNCT
admet-505	403	11	including	include	VERB
admet-505	403	12	clofazimine	clofazimine	NOUN
admet-505	403	13	)	)	PUNCT
admet-505	403	14	studied	study	VERB
admet-505	403	15	by	by	ADP
admet-505	403	16	fahelelbom	fahelelbom	ADJ
admet-505	403	17	et	et	PROPN
admet-505	403	18	al	al	PROPN
admet-505	403	19	.	.	PUNCT
admet-505	404	1	[	[	X
admet-505	404	2	30	30	NUM
admet-505	404	3	]	]	PUNCT
admet-505	404	4	were	be	AUX
admet-505	404	5	taken	take	VERB
admet-505	404	6	directly	directly	ADV
admet-505	404	7	from	from	ADP
admet-505	404	8	a	a	DET
admet-505	404	9	plot	plot	NOUN
admet-505	404	10	;	;	PUNCT
admet-505	404	11	details	detail	NOUN
admet-505	404	12	of	of	ADP
admet-505	404	13	their	their	PRON
admet-505	404	14	determination	determination	NOUN
admet-505	404	15	were	be	AUX
admet-505	404	16	not	not	PART
admet-505	404	17	reported	report	VERB
admet-505	404	18	in	in	ADP
admet-505	404	19	the	the	DET
admet-505	404	20	publication	publication	NOUN
admet-505	404	21	.	.	PUNCT
admet-505	405	1	in	in	ADP
admet-505	405	2	just	just	ADV
admet-505	405	3	one	one	NUM
admet-505	405	4	instance	instance	NOUN
admet-505	405	5	,	,	PUNCT
admet-505	405	6	the	the	DET
admet-505	405	7	k	k	PROPN
admet-505	405	8	values	value	NOUN
admet-505	405	9	were	be	AUX
admet-505	405	10	calculated	calculate	VERB
admet-505	405	11	from	from	ADP
admet-505	405	12	aqueous	aqueous	ADJ
admet-505	405	13	micellar	micellar	NOUN
admet-505	405	14	systems	system	NOUN
admet-505	405	15	(	(	PUNCT
admet-505	405	16	without	without	ADP
admet-505	405	17	drug	drug	NOUN
admet-505	405	18	precipitate	precipitate	NOUN
admet-505	405	19	):	):	PUNCT
admet-505	405	20	garrone	garrone	NOUN
admet-505	405	21	et	et	NOUN
admet-505	405	22	al	al	PROPN
admet-505	405	23	.	.	PUNCT
admet-505	406	1	[	[	X
admet-505	406	2	31	31	NUM
admet-505	406	3	]	]	PUNCT
admet-505	406	4	reported	report	VERB
admet-505	406	5	sds	sds	PROPN
admet-505	406	6	-	-	PUNCT
admet-505	406	7	water	water	NOUN
admet-505	406	8	partition	partition	NOUN
admet-505	406	9	coefficients	coefficient	NOUN
admet-505	406	10	,	,	PUNCT
admet-505	406	11	psds	psds	NOUN
admet-505	406	12	-	-	PUNCT
admet-505	406	13	water	water	NOUN
admet-505	406	14	,	,	PUNCT
admet-505	406	15	for	for	ADP
admet-505	406	16	a	a	DET
admet-505	406	17	series	series	NOUN
admet-505	406	18	of	of	ADP
admet-505	406	19	benzoic	benzoic	ADJ
admet-505	406	20	acid	acid	NOUN
admet-505	406	21	derivatives	derivative	NOUN
admet-505	406	22	,	,	PUNCT
admet-505	406	23	determined	determine	VERB
admet-505	406	24	from	from	ADP
admet-505	406	25	shifts	shift	NOUN
admet-505	406	26	in	in	ADP
admet-505	406	27	the	the	DET
admet-505	406	28	pka	pka	PROPN
admet-505	406	29	values	value	NOUN
admet-505	406	30	as	as	ADP
admet-505	406	31	a	a	DET
admet-505	406	32	function	function	NOUN
admet-505	406	33	of	of	ADP
admet-505	406	34	the	the	DET
admet-505	406	35	sds	sds	PROPN
admet-505	406	36	added	add	VERB
admet-505	406	37	.	.	PUNCT
admet-505	407	1	calculated	calculate	VERB
admet-505	407	2	k	k	PROPN
admet-505	407	3	=	=	PUNCT
admet-505	407	4	psds	psds	NOUN
admet-505	407	5	-	-	PUNCT
admet-505	407	6	water∙s0∙vm	water∙s0∙vm	NOUN
admet-505	407	7	/(1	/(1	PUNCT
admet-505	408	1	[	[	X
admet-505	408	2	sds]tot∙vm	sds]tot∙vm	NOUN
admet-505	408	3	)	)	PUNCT
admet-505	409	1	[	[	X
admet-505	409	2	12	12	NUM
admet-505	409	3	]	]	PUNCT
admet-505	409	4	,	,	PUNCT
admet-505	409	5	where	where	SCONJ
admet-505	409	6	the	the	DET
admet-505	409	7	partial	partial	ADJ
admet-505	409	8	molar	molar	ADJ
admet-505	409	9	volume	volume	NOUN
admet-505	409	10	of	of	ADP
admet-505	409	11	sds	sds	PROPN
admet-505	409	12	,	,	PUNCT
admet-505	409	13	vm	vm	PROPN
admet-505	409	14	,	,	PUNCT
admet-505	409	15	was	be	AUX
admet-505	409	16	taken	take	VERB
admet-505	409	17	to	to	PART
admet-505	409	18	be	be	AUX
admet-505	409	19	0.26	0.26	NUM
admet-505	409	20	m-1	m-1	NOUN
admet-505	410	1	[	[	X
admet-505	410	2	31	31	NUM
admet-505	410	3	]	]	PUNCT
admet-505	410	4	.	.	PUNCT
admet-505	411	1	intrinsic	intrinsic	ADJ
admet-505	411	2	solubility	solubility	NOUN
admet-505	411	3	s0	s0	PROPN
admet-505	411	4	constants	constants	PROPN
admet-505	411	5	drug	drug	NOUN
admet-505	411	6	intrinsic	intrinsic	ADJ
admet-505	411	7	solubility	solubility	NOUN
admet-505	411	8	values	value	NOUN
admet-505	411	9	(	(	PUNCT
admet-505	411	10	s0	s0	PROPN
admet-505	411	11	)	)	PUNCT
admet-505	411	12	were	be	AUX
admet-505	411	13	taken	take	VERB
admet-505	411	14	from	from	ADP
admet-505	411	15	the	the	DET
admet-505	411	16	literature	literature	NOUN
admet-505	411	17	,	,	PUNCT
admet-505	411	18	averaged	average	VERB
admet-505	411	19	where	where	SCONJ
admet-505	411	20	replicate	replicate	NOUN
admet-505	411	21	sources	source	NOUN
admet-505	411	22	https://automeris.io/webplotdigitizer/	https://automeris.io/webplotdigitizer/	PUNCT
admet-505	411	23	alex	alex	PROPN
admet-505	411	24	avdeef	avdeef	PROPN
admet-505	411	25	admet	admet	PROPN
admet-505	411	26	&	&	CCONJ
admet-505	411	27	dmpk	dmpk	PROPN
admet-505	411	28	6(2	6(2	NUM
admet-505	411	29	)	)	PUNCT
admet-505	411	30	(	(	PUNCT
admet-505	411	31	2018	2018	NUM
admet-505	411	32	)	)	PUNCT
admet-505	411	33	105	105	NUM
admet-505	411	34	-	-	SYM
admet-505	411	35	139	139	NUM
admet-505	411	36	112	112	NUM
admet-505	411	37	were	be	AUX
admet-505	411	38	available	available	ADJ
admet-505	411	39	[	[	X
admet-505	411	40	17	17	NUM
admet-505	411	41	,	,	PUNCT
admet-505	411	42	55	55	NUM
admet-505	411	43	,	,	PUNCT
admet-505	411	44	56	56	NUM
admet-505	411	45	]	]	PUNCT
admet-505	411	46	.	.	PUNCT
admet-505	412	1	most	most	ADJ
admet-505	412	2	of	of	ADP
admet-505	412	3	the	the	DET
admet-505	412	4	reported	report	VERB
admet-505	412	5	values	value	NOUN
admet-505	412	6	(	(	PUNCT
admet-505	412	7	e.g.	e.g.	ADV
admet-505	412	8	,	,	PUNCT
admet-505	412	9	in	in	ADP
admet-505	412	10	the	the	DET
admet-505	412	11	handbook	handbook	NOUN
admet-505	412	12	of	of	ADP
admet-505	412	13	aqueous	aqueous	ADJ
admet-505	412	14	solubility	solubility	NOUN
admet-505	412	15	data	datum	NOUN
admet-505	412	16	[	[	X
admet-505	412	17	54	54	NUM
admet-505	412	18	]	]	PUNCT
admet-505	412	19	)	)	PUNCT
admet-505	412	20	have	have	AUX
admet-505	412	21	been	be	AUX
admet-505	412	22	published	publish	VERB
admet-505	412	23	as	as	ADP
admet-505	412	24	concentrations	concentration	NOUN
admet-505	412	25	(	(	PUNCT
admet-505	412	26	sw	sw	NOUN
admet-505	412	27	)	)	PUNCT
admet-505	412	28	in	in	ADP
admet-505	412	29	saturated	saturate	VERB
admet-505	412	30	aqueous	aqueous	ADJ
admet-505	412	31	solutions	solution	NOUN
admet-505	412	32	of	of	ADP
admet-505	412	33	the	the	DET
admet-505	412	34	drug	drug	NOUN
admet-505	412	35	,	,	PUNCT
admet-505	412	36	added	add	VERB
admet-505	412	37	in	in	ADP
admet-505	412	38	the	the	DET
admet-505	412	39	neutral	neutral	ADJ
admet-505	412	40	form	form	NOUN
admet-505	412	41	to	to	ADP
admet-505	412	42	unbuffered	unbuffered	ADJ
admet-505	412	43	water	water	NOUN
admet-505	412	44	.	.	PUNCT
admet-505	413	1	table	table	NOUN
admet-505	413	2	1	1	NUM
admet-505	413	3	lists	list	VERB
admet-505	413	4	the	the	DET
admet-505	413	5	log	log	NOUN
admet-505	413	6	s0	s0	PROPN
admet-505	413	7	,	,	PUNCT
admet-505	413	8	adjusted	adjust	VERB
admet-505	413	9	for	for	ADP
admet-505	413	10	the	the	DET
admet-505	413	11	assay	assay	NOUN
admet-505	413	12	temperature	temperature	NOUN
admet-505	413	13	[	[	X
admet-505	413	14	26	26	NUM
admet-505	413	15	]	]	PUNCT
admet-505	413	16	.	.	PUNCT
admet-505	414	1	ionization	ionization	NOUN
admet-505	414	2	constants	constant	NOUN
admet-505	414	3	(	(	PUNCT
admet-505	414	4	pka	pka	NOUN
admet-505	414	5	)	)	PUNCT
admet-505	414	6	the	the	DET
admet-505	414	7	pka	pka	PROPN
admet-505	414	8	values	value	NOUN
admet-505	414	9	used	use	VERB
admet-505	414	10	here	here	ADV
admet-505	414	11	(	(	PUNCT
admet-505	414	12	table	table	NOUN
admet-505	414	13	1	1	NUM
admet-505	414	14	)	)	PUNCT
admet-505	414	15	were	be	AUX
admet-505	414	16	taken	take	VERB
admet-505	414	17	from	from	ADP
admet-505	414	18	the	the	DET
admet-505	414	19	wiki	wiki	PROPN
admet-505	414	20	-	-	PUNCT
admet-505	414	21	pka	pka	PROPN
admet-505	414	22	database	database	NOUN
admet-505	414	23	:	:	PUNCT
admet-505	414	24	http://www.inadme.com/wiki_pka.php/.	http://www.inadme.com/wiki_pka.php/.	PROPN
admet-505	414	25	literature	literature	PROPN
admet-505	414	26	pka	pka	PROPN
admet-505	414	27	values	value	NOUN
admet-505	414	28	are	be	AUX
admet-505	414	29	often	often	ADV
admet-505	414	30	reported	report	VERB
admet-505	414	31	at	at	ADP
admet-505	414	32	25	25	NUM
admet-505	414	33	°	°	NOUN
admet-505	414	34	c	c	NOUN
admet-505	414	35	and	and	CCONJ
admet-505	414	36	0.15	0.15	NUM
admet-505	414	37	m	m	NOUN
admet-505	414	38	ionic	ionic	ADJ
admet-505	414	39	strength	strength	NOUN
admet-505	414	40	.	.	PUNCT
admet-505	415	1	when	when	SCONJ
admet-505	415	2	the	the	DET
admet-505	415	3	assay	assay	NOUN
admet-505	415	4	temperature	temperature	NOUN
admet-505	415	5	or	or	CCONJ
admet-505	415	6	ionic	ionic	ADJ
admet-505	415	7	strength	strength	NOUN
admet-505	415	8	were	be	AUX
admet-505	415	9	different	different	ADJ
admet-505	415	10	from	from	ADP
admet-505	415	11	literature	literature	NOUN
admet-505	415	12	conditions	condition	NOUN
admet-505	415	13	,	,	PUNCT
admet-505	415	14	pka	pka	PROPN
admet-505	415	15	values	value	NOUN
admet-505	415	16	were	be	AUX
admet-505	415	17	adjusted	adjust	VERB
admet-505	415	18	to	to	PART
admet-505	415	19	match	match	VERB
admet-505	415	20	the	the	DET
admet-505	415	21	experimental	experimental	ADJ
admet-505	415	22	conditions	condition	NOUN
admet-505	415	23	,	,	PUNCT
admet-505	415	24	using	use	VERB
admet-505	415	25	stokes	stokes	PROPN
admet-505	415	26	-	-	PUNCT
admet-505	415	27	robinson	robinson	PROPN
admet-505	415	28	hydration	hydration	NOUN
admet-505	415	29	theory	theory	NOUN
admet-505	415	30	[	[	X
admet-505	415	31	21	21	NUM
admet-505	415	32	]	]	PUNCT
admet-505	415	33	for	for	ADP
admet-505	415	34	ionic	ionic	ADJ
admet-505	415	35	strength	strength	NOUN
admet-505	415	36	[	[	X
admet-505	415	37	16	16	NUM
admet-505	415	38	,	,	PUNCT
admet-505	415	39	27	27	NUM
admet-505	415	40	]	]	PUNCT
admet-505	415	41	and	and	CCONJ
admet-505	415	42	an	an	DET
admet-505	415	43	empirical	empirical	ADJ
admet-505	415	44	method	method	NOUN
admet-505	415	45	for	for	ADP
admet-505	415	46	temperature	temperature	NOUN
admet-505	415	47	[	[	X
admet-505	415	48	57	57	NUM
admet-505	415	49	]	]	PUNCT
admet-505	415	50	effects	effect	NOUN
admet-505	415	51	.	.	PUNCT
admet-505	416	1	examples	example	NOUN
admet-505	416	2	of	of	ADP
admet-505	416	3	published	publish	VERB
admet-505	416	4	solubility	solubility	NOUN
admet-505	416	5	-	-	PUNCT
admet-505	416	6	sds	sds	PROPN
admet-505	416	7	data	datum	NOUN
admet-505	416	8	figures	figure	NOUN
admet-505	416	9	2	2	NUM
admet-505	416	10	-	-	SYM
admet-505	416	11	7	7	NUM
admet-505	416	12	illustrate	illustrate	ADJ
admet-505	416	13	drug	drug	NOUN
admet-505	416	14	multi	multi	ADJ
admet-505	416	15	-	-	ADJ
admet-505	416	16	point	point	ADJ
admet-505	416	17	solubility	solubility	NOUN
admet-505	416	18	as	as	ADP
admet-505	416	19	a	a	DET
admet-505	416	20	function	function	NOUN
admet-505	416	21	of	of	ADP
admet-505	416	22	sds	sds	PROPN
admet-505	416	23	concentration	concentration	NOUN
admet-505	416	24	,	,	PUNCT
admet-505	416	25	with	with	ADP
admet-505	416	26	molecules	molecule	NOUN
admet-505	416	27	grouped	group	VERB
admet-505	416	28	according	accord	VERB
admet-505	416	29	to	to	ADP
admet-505	416	30	acid	acid	NOUN
admet-505	416	31	-	-	PUNCT
admet-505	416	32	base	base	NOUN
admet-505	416	33	characteristics	characteristic	NOUN
admet-505	416	34	.	.	PUNCT
admet-505	417	1	in	in	ADP
admet-505	417	2	the	the	DET
admet-505	417	3	figures	figure	NOUN
admet-505	417	4	,	,	PUNCT
admet-505	417	5	frames	frame	NOUN
admet-505	417	6	contain	contain	VERB
admet-505	417	7	the	the	DET
admet-505	417	8	structure	structure	NOUN
admet-505	417	9	of	of	ADP
admet-505	417	10	the	the	DET
admet-505	417	11	molecule	molecule	NOUN
admet-505	417	12	considered	consider	VERB
admet-505	417	13	,	,	PUNCT
admet-505	417	14	and	and	CCONJ
admet-505	417	15	indicate	indicate	VERB
admet-505	417	16	assay	assay	NOUN
admet-505	417	17	temperature	temperature	NOUN
admet-505	417	18	,	,	PUNCT
admet-505	417	19	solution	solution	NOUN
admet-505	417	20	makeup	makeup	NOUN
admet-505	417	21	(	(	PUNCT
admet-505	417	22	distilled	distilled	ADJ
admet-505	417	23	water	water	NOUN
admet-505	417	24	,	,	PUNCT
admet-505	417	25	or	or	CCONJ
admet-505	417	26	buffer	buffer	NOUN
admet-505	417	27	type	type	NOUN
admet-505	417	28	and	and	CCONJ
admet-505	417	29	ph	ph	NOUN
admet-505	417	30	,	,	PUNCT
admet-505	417	31	or	or	CCONJ
admet-505	417	32	whether	whether	SCONJ
admet-505	417	33	background	background	NOUN
admet-505	417	34	salt	salt	NOUN
admet-505	417	35	had	have	AUX
admet-505	417	36	been	be	AUX
admet-505	417	37	added	add	VERB
admet-505	417	38	)	)	PUNCT
admet-505	417	39	,	,	PUNCT
admet-505	417	40	equilibration	equilibration	NOUN
admet-505	417	41	times	time	NOUN
admet-505	417	42	,	,	PUNCT
admet-505	417	43	pka	pka	PROPN
admet-505	417	44	(	(	PUNCT
admet-505	417	45	acids	acid	NOUN
admet-505	417	46	underlined	underline	VERB
admet-505	417	47	)	)	PUNCT
admet-505	417	48	,	,	PUNCT
admet-505	417	49	log	log	NOUN
admet-505	417	50	s0	s0	PROPN
admet-505	417	51	,	,	PUNCT
admet-505	417	52	and	and	CCONJ
admet-505	417	53	log	log	VERB
admet-505	417	54	poct	poct	NOUN
admet-505	417	55	constants	constant	NOUN
admet-505	417	56	.	.	PUNCT
admet-505	418	1	each	each	DET
admet-505	418	2	curve	curve	NOUN
admet-505	418	3	comprises	comprise	VERB
admet-505	418	4	a	a	DET
admet-505	418	5	horizontal	horizontal	ADJ
admet-505	418	6	region	region	NOUN
admet-505	418	7	(	(	PUNCT
admet-505	418	8	[	[	X
admet-505	418	9	sds	sds	X
admet-505	418	10	]	]	X
admet-505	418	11	<	<	X
admet-505	418	12	cmc	cmc	PROPN
admet-505	418	13	)	)	PUNCT
admet-505	418	14	and	and	CCONJ
admet-505	418	15	a	a	DET
admet-505	418	16	region	region	NOUN
admet-505	418	17	of	of	ADP
admet-505	418	18	increasing	increase	VERB
admet-505	418	19	solubility	solubility	NOUN
admet-505	418	20	(	(	PUNCT
admet-505	418	21	[	[	X
admet-505	418	22	sds	sds	X
admet-505	418	23	]	]	PUNCT
admet-505	418	24	>	>	X
admet-505	418	25	cmc	cmc	PROPN
admet-505	418	26	)	)	PUNCT
admet-505	418	27	.	.	PUNCT
admet-505	419	1	the	the	DET
admet-505	419	2	points	point	NOUN
admet-505	419	3	in	in	ADP
admet-505	419	4	the	the	DET
admet-505	419	5	latter	latter	ADJ
admet-505	419	6	region	region	NOUN
admet-505	419	7	were	be	AUX
admet-505	419	8	selected	select	VERB
admet-505	419	9	for	for	ADP
admet-505	419	10	linear	linear	NOUN
admet-505	419	11	/	/	SYM
admet-505	419	12	curvilinear	curvilinear	ADJ
admet-505	419	13	regression	regression	NOUN
admet-505	419	14	.	.	PUNCT
admet-505	420	1	the	the	DET
admet-505	420	2	solid	solid	ADJ
admet-505	420	3	red	red	ADJ
admet-505	420	4	curves	curve	NOUN
admet-505	420	5	are	be	AUX
admet-505	420	6	the	the	DET
admet-505	420	7	connections	connection	NOUN
admet-505	420	8	of	of	ADP
admet-505	420	9	two	two	NUM
admet-505	420	10	curves	curve	NOUN
admet-505	420	11	:	:	PUNCT
admet-505	420	12	the	the	DET
admet-505	420	13	regression	regression	NOUN
admet-505	420	14	-	-	PUNCT
admet-505	420	15	fitted	fit	VERB
admet-505	420	16	curve	curve	NOUN
admet-505	420	17	and	and	CCONJ
admet-505	420	18	the	the	DET
admet-505	420	19	horizontal	horizontal	ADJ
admet-505	420	20	lines	line	NOUN
admet-505	420	21	where	where	SCONJ
admet-505	420	22	solubility	solubility	NOUN
admet-505	420	23	is	be	AUX
admet-505	420	24	not	not	PART
admet-505	420	25	appreciably	appreciably	ADV
admet-505	420	26	affected	affect	VERB
admet-505	420	27	by	by	ADP
admet-505	420	28	sds	sds	PROPN
admet-505	420	29	.	.	PUNCT
admet-505	421	1	at	at	ADP
admet-505	421	2	the	the	DET
admet-505	421	3	intersection	intersection	NOUN
admet-505	421	4	of	of	ADP
admet-505	421	5	these	these	DET
admet-505	421	6	curves	curve	NOUN
admet-505	421	7	(	(	PUNCT
admet-505	421	8	indicated	indicate	VERB
admet-505	421	9	by	by	ADP
admet-505	421	10	arrows	arrow	NOUN
admet-505	421	11	)	)	PUNCT
admet-505	421	12	are	be	AUX
admet-505	421	13	concentrations	concentration	NOUN
admet-505	421	14	which	which	PRON
admet-505	421	15	may	may	AUX
admet-505	421	16	be	be	AUX
admet-505	421	17	taken	take	VERB
admet-505	421	18	as	as	ADP
admet-505	421	19	the	the	DET
admet-505	421	20	cmc	cmc	NOUN
admet-505	421	21	values	value	NOUN
admet-505	421	22	.	.	PUNCT
admet-505	422	1	the	the	DET
admet-505	422	2	slopes	slope	NOUN
admet-505	422	3	of	of	ADP
admet-505	422	4	the	the	DET
admet-505	422	5	curves	curve	NOUN
admet-505	422	6	in	in	ADP
admet-505	422	7	the	the	DET
admet-505	422	8	[	[	X
admet-505	422	9	sds	sds	X
admet-505	422	10	]	]	PUNCT
admet-505	422	11	>	>	X
admet-505	422	12	cmc	cmc	PROPN
admet-505	422	13	region	region	NOUN
admet-505	422	14	were	be	AUX
admet-505	422	15	taken	take	VERB
admet-505	422	16	to	to	PART
admet-505	422	17	be	be	AUX
admet-505	422	18	the	the	DET
admet-505	422	19	k	k	PROPN
admet-505	422	20	values	value	NOUN
admet-505	422	21	(	(	PUNCT
admet-505	422	22	table	table	NOUN
admet-505	422	23	1	1	NUM
admet-505	422	24	)	)	PUNCT
admet-505	422	25	and	and	CCONJ
admet-505	422	26	are	be	AUX
admet-505	422	27	indicated	indicate	VERB
admet-505	422	28	in	in	ADP
admet-505	422	29	units	unit	NOUN
admet-505	422	30	of	of	ADP
admet-505	422	31	moldrug	moldrug	NOUN
admet-505	422	32	/	/	SYM
admet-505	422	33	molsds	molsds	NOUN
admet-505	422	34	.	.	PUNCT
admet-505	423	1	in	in	ADP
admet-505	423	2	cases	case	NOUN
admet-505	423	3	the	the	DET
admet-505	423	4	curves	curve	NOUN
admet-505	423	5	were	be	AUX
admet-505	423	6	nonlinear	nonlinear	ADJ
admet-505	423	7	,	,	PUNCT
admet-505	423	8	a	a	DET
admet-505	423	9	parabolic	parabolic	ADJ
admet-505	423	10	fit	fit	NOUN
admet-505	423	11	was	be	AUX
admet-505	423	12	used	use	VERB
admet-505	423	13	,	,	PUNCT
admet-505	423	14	and	and	CCONJ
admet-505	423	15	the	the	DET
admet-505	423	16	indicated	indicate	VERB
admet-505	423	17	slopes	slope	NOUN
admet-505	423	18	were	be	AUX
admet-505	423	19	evaluated	evaluate	VERB
admet-505	423	20	at	at	ADP
admet-505	423	21	[	[	X
admet-505	423	22	sds	sds	X
admet-505	423	23	]	]	X
admet-505	423	24	=	=	SYM
admet-505	423	25	cmc	cmc	PROPN
admet-505	423	26	.	.	PUNCT
admet-505	424	1	http://www.in-adme.com/wiki_pka.php/	http://www.in-adme.com/wiki_pka.php/	PROPN
admet-505	424	2	http://www.in-adme.com/wiki_pka.php/	http://www.in-adme.com/wiki_pka.php/	PROPN
admet-505	424	3	admet	admet	PROPN
admet-505	424	4	&	&	CCONJ
admet-505	424	5	dmpk	dmpk	PROPN
admet-505	424	6	6(2	6(2	NUM
admet-505	424	7	)	)	PUNCT
admet-505	424	8	(	(	PUNCT
admet-505	424	9	2018	2018	NUM
admet-505	424	10	)	)	PUNCT
admet-505	424	11	105	105	NUM
admet-505	424	12	-	-	SYM
admet-505	424	13	139	139	NUM
admet-505	424	14	cocrystal	cocrystal	ADJ
admet-505	424	15	solubility	solubility	NOUN
admet-505	424	16	-	-	PUNCT
admet-505	424	17	ph	ph	VERB
admet-505	424	18	,	,	PUNCT
admet-505	424	19	drug	drug	NOUN
admet-505	424	20	solubilization	solubilization	NOUN
admet-505	424	21	capacity	capacity	NOUN
admet-505	424	22	of	of	ADP
admet-505	424	23	sds	sds	PROPN
admet-505	424	24	,	,	PUNCT
admet-505	424	25	mass	mass	ADJ
admet-505	424	26	action	action	NOUN
admet-505	424	27	model	model	NOUN
admet-505	424	28	doi	doi	PROPN
admet-505	424	29	:	:	PUNCT
admet-505	424	30	10.5599	10.5599	NUM
admet-505	424	31	/	/	SYM
admet-505	424	32	admet.505	admet.505	PROPN
admet-505	424	33	113	113	NUM
admet-505	424	34	table	table	NOUN
admet-505	424	35	1	1	NUM
admet-505	424	36	.	.	PUNCT
admet-505	424	37	drug	drug	NOUN
admet-505	424	38	solubilization	solubilization	NOUN
admet-505	424	39	capacity	capacity	NOUN
admet-505	424	40	(	(	PUNCT
admet-505	424	41	k	k	NOUN
admet-505	424	42	)	)	PUNCT
admet-505	424	43	and	and	CCONJ
admet-505	424	44	other	other	ADJ
admet-505	424	45	physicochemical	physicochemical	ADJ
admet-505	424	46	parameters	parameter	NOUN
admet-505	424	47	a	a	DET
admet-505	424	48	compound	compound	NOUN
admet-505	424	49	type	type	NOUN
admet-505	424	50	pka	pka	PROPN
admet-505	424	51	(	(	PUNCT
admet-505	424	52	acid	acid	PROPN
admet-505	424	53	)	)	PUNCT
admet-505	424	54	pka	pka	PROPN
admet-505	424	55	(	(	PUNCT
admet-505	424	56	base	base	NOUN
admet-505	424	57	)	)	PUNCT
admet-505	424	58	t(`c	t(`c	PROPN
admet-505	424	59	)	)	PUNCT
admet-505	425	1	k	k	PROPN
admet-505	425	2	(	(	PUNCT
admet-505	425	3	calc	calc	NOUN
admet-505	425	4	)	)	PUNCT
admet-505	425	5	b	b	PROPN
admet-505	426	1	k	k	PROPN
admet-505	426	2	(	(	PUNCT
admet-505	426	3	obs	obs	PROPN
admet-505	426	4	)	)	PUNCT
admet-505	426	5	c	c	PROPN
admet-505	426	6	±	±	NUM
admet-505	426	7	sd	sd	ADP
admet-505	426	8	n	n	PROPN
admet-505	426	9	d	d	NOUN
admet-505	426	10	log	log	NOUN
admet-505	426	11	kn	kn	PROPN
admet-505	426	12	e	e	PROPN
admet-505	426	13	n	n	PROPN
admet-505	426	14	fbm	fbm	NOUN
admet-505	426	15	nd	nd	PRON
admet-505	426	16	log	log	VERB
admet-505	426	17	poct	poct	PROPN
admet-505	426	18	log	log	NOUN
admet-505	426	19	s0	s0	PROPN
admet-505	426	20	±sd	±sd	PROPN
admet-505	426	21	n	n	CCONJ
admet-505	426	22	σα2	σα2	NOUN
admet-505	426	23	h	h	NOUN
admet-505	426	24	σβ2	σβ2	VERB
admet-505	426	25	h	h	PROPN
admet-505	426	26	π2	π2	PROPN
admet-505	426	27	r2	r2	PROPN
admet-505	426	28	vx	vx	PROPN
admet-505	426	29	comments	comment	NOUN
admet-505	426	30	ref	ref	VERB
admet-505	426	31	artemisinin	artemisinin	PROPN
admet-505	426	32	n	n	CCONJ
admet-505	426	33	22	22	NUM
admet-505	426	34	0.191	0.191	NUM
admet-505	426	35	0.191	0.191	NUM
admet-505	426	36	0.013	0.013	NUM
admet-505	426	37	11	11	NUM
admet-505	426	38	45	45	NUM
admet-505	426	39	12	12	NUM
admet-505	426	40	0.99	0.99	NUM
admet-505	426	41	11.8	11.8	NUM
admet-505	426	42	2.90	2.90	NUM
admet-505	426	43	-3.61	-3.61	NOUN
admet-505	426	44	0.01	0.01	NUM
admet-505	426	45	1	1	NUM
admet-505	426	46	0.00	0.00	NUM
admet-505	426	47	1.27	1.27	NUM
admet-505	426	48	1.96	1.96	NUM
admet-505	426	49	1.11	1.11	NUM
admet-505	426	50	2.04	2.04	NUM
admet-505	426	51	[	[	X
admet-505	426	52	28	28	NUM
admet-505	426	53	]	]	X
admet-505	426	54	atazanavir	atazanavir	PROPN
admet-505	426	55	b	b	PROPN
admet-505	426	56	4.52	4.52	NUM
admet-505	426	57	37	37	NUM
admet-505	426	58	0.017	0.017	NUM
admet-505	426	59	0.0056	0.0056	NUM
admet-505	426	60	0.0002	0.0002	NUM
admet-505	426	61	9	9	NUM
admet-505	426	62	5.3	5.3	NUM
admet-505	426	63	1	1	NUM
admet-505	426	64	0.35	0.35	NUM
admet-505	426	65	0.35	0.35	NUM
admet-505	426	66	4.54	4.54	NUM
admet-505	426	67	-5.53	-5.53	NOUN
admet-505	426	68	0.41	0.41	NUM
admet-505	426	69	2	2	NUM
admet-505	426	70	1.14	1.14	NUM
admet-505	426	71	3.90	3.90	NUM
admet-505	426	72	5.10	5.10	NUM
admet-505	426	73	3.54	3.54	NUM
admet-505	426	74	5.59	5.59	NUM
admet-505	426	75	[	[	X
admet-505	426	76	29	29	NUM
admet-505	426	77	]	]	SYM
admet-505	426	78	b3640	b3640	PROPN
admet-505	426	79	(	(	PUNCT
admet-505	426	80	iminophenazine	iminophenazine	PROPN
admet-505	426	81	)	)	PUNCT
admet-505	426	82	b	b	PROPN
admet-505	426	83	8.09	8.09	NUM
admet-505	426	84	37	37	NUM
admet-505	426	85	0.00258	0.00258	NUM
admet-505	426	86	0.00040	0.00040	NUM
admet-505	426	87	5.4	5.4	NUM
admet-505	426	88	1	1	NUM
admet-505	426	89	0.02	0.02	NUM
admet-505	426	90	5	5	NUM
admet-505	426	91	0.02	0.02	NUM
admet-505	426	92	5	5	NUM
admet-505	426	93	3.58	3.58	NUM
admet-505	426	94	-7.04	-7.04	NUM
admet-505	426	95	0.32	0.32	NUM
admet-505	426	96	1.71	1.71	NUM
admet-505	426	97	2.61	2.61	NUM
admet-505	426	98	3.85	3.85	NUM
admet-505	426	99	3.87	3.87	NUM
admet-505	426	100	[	[	X
admet-505	426	101	30	30	NUM
admet-505	426	102	]	]	X
admet-505	426	103	b3770	b3770	NOUN
admet-505	426	104	(	(	PUNCT
admet-505	426	105	iminophenazine	iminophenazine	ADJ
admet-505	426	106	)	)	PUNCT
admet-505	426	107	b	b	PROPN
admet-505	426	108	8.80	8.80	NUM
admet-505	426	109	37	37	NUM
admet-505	426	110	0.00050	0.00050	NUM
admet-505	426	111	0.00024	0.00024	NUM
admet-505	426	112	6.5	6.5	NUM
admet-505	426	113	1	1	NUM
admet-505	426	114	0.01	0.01	NUM
admet-505	426	115	5	5	NUM
admet-505	426	116	0.01	0.01	NUM
admet-505	426	117	5	5	NUM
admet-505	426	118	4.78	4.78	NUM
admet-505	426	119	-8.35	-8.35	NUM
admet-505	426	120	0.19	0.19	NUM
admet-505	426	121	1.74	1.74	NUM
admet-505	426	122	2.64	2.64	NUM
admet-505	426	123	3.86	3.86	NUM
admet-505	426	124	4.15	4.15	NUM
admet-505	426	125	[	[	X
admet-505	426	126	30	30	NUM
admet-505	426	127	]	]	X
admet-505	426	128	b3785	b3785	PROPN
admet-505	426	129	(	(	PUNCT
admet-505	426	130	iminophenazine	iminophenazine	PROPN
admet-505	426	131	)	)	PUNCT
admet-505	426	132	b	b	PROPN
admet-505	426	133	8.60	8.60	NUM
admet-505	426	134	37	37	NUM
admet-505	426	135	0.00084	0.00084	NUM
admet-505	426	136	0.00028	0.00028	NUM
admet-505	426	137	6.2	6.2	NUM
admet-505	426	138	1	1	NUM
admet-505	426	139	0.01	0.01	NUM
admet-505	426	140	8	8	NUM
admet-505	426	141	0.01	0.01	NUM
admet-505	426	142	8	8	NUM
admet-505	426	143	4.39	4.39	NUM
admet-505	426	144	-7.94	-7.94	NUM
admet-505	426	145	0.19	0.19	NUM
admet-505	426	146	1.73	1.73	NUM
admet-505	426	147	2.64	2.64	NUM
admet-505	426	148	3.86	3.86	NUM
admet-505	426	149	4.01	4.01	NUM
admet-505	426	150	[	[	X
admet-505	426	151	30	30	NUM
admet-505	426	152	]	]	PUNCT
admet-505	426	153	b628	b628	PROPN
admet-505	426	154	(	(	PUNCT
admet-505	426	155	iminophenazine	iminophenazine	PROPN
admet-505	426	156	)	)	PUNCT
admet-505	426	157	b	b	PROPN
admet-505	426	158	8.48	8.48	NUM
admet-505	426	159	37	37	NUM
admet-505	426	160	0.00283	0.00283	NUM
admet-505	426	161	0.00070	0.00070	NUM
admet-505	426	162	5.6	5.6	NUM
admet-505	426	163	1	1	NUM
admet-505	426	164	0.04	0.04	NUM
admet-505	426	165	3	3	NUM
admet-505	426	166	0.04	0.04	NUM
admet-505	426	167	3	3	NUM
admet-505	426	168	3.31	3.31	NUM
admet-505	426	169	-6.97	-6.97	NOUN
admet-505	426	170	0.19	0.19	NUM
admet-505	426	171	1.23	1.23	NUM
admet-505	426	172	2.39	2.39	NUM
admet-505	426	173	3.6	3.6	NUM
admet-505	426	174	3.03	3.03	NUM
admet-505	426	175	[	[	X
admet-505	426	176	30	30	NUM
admet-505	426	177	]	]	PUNCT
admet-505	426	178	b826	b826	PROPN
admet-505	426	179	(	(	PUNCT
admet-505	426	180	iminophenazine	iminophenazine	PROPN
admet-505	426	181	)	)	PUNCT
admet-505	426	182	b	b	NOUN
admet-505	426	183	8.81	8.81	NUM
admet-505	426	184	37	37	NUM
admet-505	426	185	0.00060	0.00060	NUM
admet-505	426	186	0.00027	0.00027	NUM
admet-505	426	187	6.4	6.4	NUM
admet-505	426	188	1	1	NUM
admet-505	426	189	0.01	0.01	NUM
admet-505	426	190	7	7	NUM
admet-505	426	191	0.01	0.01	NUM
admet-505	426	192	7	7	NUM
admet-505	426	193	4.50	4.50	NUM
admet-505	426	194	-8.21	-8.21	NUM
admet-505	426	195	0.19	0.19	NUM
admet-505	426	196	1.76	1.76	NUM
admet-505	426	197	2.55	2.55	NUM
admet-505	426	198	3.65	3.65	NUM
admet-505	426	199	4.12	4.12	NUM
admet-505	426	200	[	[	SYM
admet-505	426	201	30	30	NUM
admet-505	426	202	]	]	X
admet-505	426	203	benzoic	benzoic	NOUN
admet-505	426	204	acid	acid	NOUN
admet-505	426	205	a	a	DET
admet-505	426	206	3.96	3.96	NUM
admet-505	426	207	35	35	NUM
admet-505	426	208	1.038	1.038	NUM
admet-505	426	209	0.769	0.769	NUM
admet-505	426	210	0.0473	0.0473	NUM
admet-505	426	211	6	6	NUM
admet-505	426	212	71	71	NUM
admet-505	426	213	48	48	NUM
admet-505	426	214	0.99	0.99	NUM
admet-505	426	215	47.7	47.7	NUM
admet-505	426	216	1.87	1.87	NUM
admet-505	426	217	-1.44	-1.44	NUM
admet-505	426	218	0.04	0.04	NUM
admet-505	426	219	13	13	NUM
admet-505	426	220	0.57	0.57	NUM
admet-505	426	221	0.44	0.44	NUM
admet-505	426	222	1.08	1.08	NUM
admet-505	426	223	0.75	0.75	NUM
admet-505	426	224	0.93	0.93	NUM
admet-505	426	225	[	[	X
admet-505	426	226	31	31	NUM
admet-505	426	227	]	]	PUNCT
admet-505	426	228	benzoic	benzoic	PROPN
admet-505	426	229	acid,3	acid,3	PROPN
admet-505	426	230	-	-	PUNCT
admet-505	426	231	cla	cla	PROPN
admet-505	426	232	3.82	3.82	NUM
admet-505	426	233	35	35	NUM
admet-505	426	234	0.359	0.359	NUM
admet-505	426	235	0.266	0.266	NUM
admet-505	426	236	0.0258	0.0258	NUM
admet-505	426	237	6	6	NUM
admet-505	426	238	43	43	NUM
admet-505	426	239	17	17	NUM
admet-505	426	240	0.97	0.97	NUM
admet-505	426	241	16.5	16.5	NUM
admet-505	426	242	2.70	2.70	NUM
admet-505	426	243	-2.43	-2.43	NUM
admet-505	426	244	0.20	0.20	NUM
admet-505	426	245	1	1	NUM
admet-505	426	246	0.64	0.64	NUM
admet-505	426	247	0.44	0.44	NUM
admet-505	426	248	1.16	1.16	NUM
admet-505	426	249	0.90	0.90	NUM
admet-505	426	250	1.05	1.05	NUM
admet-505	426	251	[	[	X
admet-505	426	252	31	31	NUM
admet-505	426	253	]	]	PUNCT
admet-505	426	254	benzoic	benzoic	PROPN
admet-505	426	255	acid,3	acid,3	PROPN
admet-505	426	256	-	-	PUNCT
admet-505	426	257	fa	fa	PROPN
admet-505	426	258	3.86	3.86	NUM
admet-505	426	259	35	35	NUM
admet-505	426	260	0.620	0.620	NUM
admet-505	426	261	0.408	0.408	NUM
admet-505	426	262	0.0234	0.0234	NUM
admet-505	426	263	6	6	NUM
admet-505	426	264	50	50	NUM
admet-505	426	265	26	26	NUM
admet-505	426	266	0.97	0.97	NUM
admet-505	426	267	25.3	25.3	NUM
admet-505	426	268	2.15	2.15	NUM
admet-505	426	269	-1.86	-1.86	NUM
admet-505	426	270	0.20	0.20	NUM
admet-505	426	271	1	1	NUM
admet-505	426	272	0.64	0.64	NUM
admet-505	426	273	0.45	0.45	NUM
admet-505	426	274	1.04	1.04	NUM
admet-505	426	275	0.67	0.67	NUM
admet-505	426	276	0.95	0.95	NUM
admet-505	426	277	[	[	X
admet-505	426	278	31	31	NUM
admet-505	426	279	]	]	PUNCT
admet-505	426	280	benzoic	benzoic	PROPN
admet-505	426	281	acid,3	acid,3	PROPN
admet-505	426	282	-	-	PUNCT
admet-505	426	283	hoa	hoa	NOUN
admet-505	426	284	4.09	4.09	NUM
admet-505	426	285	35	35	NUM
admet-505	426	286	0.672	0.672	NUM
admet-505	426	287	1.486	1.486	NUM
admet-505	426	288	0.2163	0.2163	NUM
admet-505	426	289	6	6	NUM
admet-505	426	290	102	102	NUM
admet-505	426	291	93	93	NUM
admet-505	426	292	0.99	0.99	NUM
admet-505	426	293	92.1	92.1	NUM
admet-505	426	294	1.49	1.49	NUM
admet-505	426	295	-1.08	-1.08	NUM
admet-505	426	296	0.04	0.04	NUM
admet-505	426	297	4	4	NUM
admet-505	426	298	1.06	1.06	NUM
admet-505	426	299	0.72	0.72	NUM
admet-505	426	300	1.29	1.29	NUM
admet-505	426	301	0.98	0.98	NUM
admet-505	426	302	0.99	0.99	NUM
admet-505	426	303	[	[	X
admet-505	426	304	31	31	NUM
admet-505	426	305	]	]	PUNCT
admet-505	426	306	benzoic	benzoic	PROPN
admet-505	426	307	acid,3	acid,3	PROPN
admet-505	426	308	-	-	PUNCT
admet-505	426	309	no2a	no2a	PROPN
admet-505	426	310	3.40	3.40	NUM
admet-505	426	311	35	35	NUM
admet-505	426	312	0.781	0.781	NUM
admet-505	426	313	0.870	0.870	NUM
admet-505	426	314	0.1656	0.1656	NUM
admet-505	426	315	6	6	NUM
admet-505	426	316	91	91	NUM
admet-505	426	317	54	54	NUM
admet-505	426	318	0.99	0.99	NUM
admet-505	426	319	9	9	NUM
admet-505	426	320	54.0	54.0	NUM
admet-505	426	321	1.82	1.82	NUM
admet-505	426	322	-1.62	-1.62	NUM
admet-505	426	323	0.09	0.09	NUM
admet-505	426	324	6	6	NUM
admet-505	426	325	0.64	0.64	NUM
admet-505	426	326	0.54	0.54	NUM
admet-505	426	327	1.65	1.65	NUM
admet-505	426	328	1.02	1.02	NUM
admet-505	426	329	1.11	1.11	NUM
admet-505	426	330	[	[	X
admet-505	426	331	31	31	NUM
admet-505	426	332	]	]	PUNCT
admet-505	426	333	benzoic	benzoic	ADJ
admet-505	426	334	acid,4	acid,4	NOUN
admet-505	426	335	-	-	PUNCT
admet-505	426	336	bra	bra	NOUN
admet-505	426	337	3.98	3.98	NUM
admet-505	426	338	35	35	NUM
admet-505	426	339	0.128	0.128	NUM
admet-505	426	340	0.034	0.034	NUM
admet-505	426	341	0.0029	0.0029	NUM
admet-505	426	342	5	5	NUM
admet-505	426	343	11	11	NUM
admet-505	426	344	3	3	NUM
admet-505	426	345	0.71	0.71	NUM
admet-505	426	346	2.1	2.1	NUM
admet-505	426	347	2.85	2.85	NUM
admet-505	426	348	-3.47	-3.47	NOUN
admet-505	426	349	0.16	0.16	NUM
admet-505	426	350	2	2	NUM
admet-505	426	351	0.66	0.66	NUM
admet-505	426	352	0.44	0.44	NUM
admet-505	426	353	1.24	1.24	NUM
admet-505	426	354	1.08	1.08	NUM
admet-505	426	355	1.11	1.11	NUM
admet-505	426	356	[	[	X
admet-505	426	357	31	31	NUM
admet-505	426	358	]	]	PUNCT
admet-505	426	359	benzoic	benzoic	ADJ
admet-505	426	360	acid,4	acid,4	NOUN
admet-505	426	361	-	-	PUNCT
admet-505	426	362	cla	cla	PROPN
admet-505	426	363	3.84	3.84	NUM
admet-505	426	364	35	35	NUM
admet-505	426	365	0.177	0.177	NUM
admet-505	426	366	0.056	0.056	NUM
admet-505	426	367	0.0029	0.0029	NUM
admet-505	426	368	6	6	NUM
admet-505	426	369	13	13	NUM
admet-505	426	370	4	4	NUM
admet-505	426	371	0.87	0.87	NUM
admet-505	426	372	3.5	3.5	NUM
admet-505	426	373	2.74	2.74	NUM
admet-505	426	374	-3.13	-3.13	NUM
admet-505	426	375	0.20	0.20	NUM
admet-505	426	376	1	1	NUM
admet-505	426	377	0.66	0.66	NUM
admet-505	426	378	0.44	0.44	NUM
admet-505	426	379	1.16	1.16	NUM
admet-505	426	380	0.90	0.90	NUM
admet-505	426	381	1.05	1.05	NUM
admet-505	426	382	[	[	X
admet-505	426	383	31	31	NUM
admet-505	426	384	]	]	PUNCT
admet-505	426	385	benzoic	benzoic	ADJ
admet-505	426	386	acid,4	acid,4	NOUN
admet-505	426	387	-	-	PUNCT
admet-505	426	388	cna	cna	PROPN
admet-505	426	389	3.48	3.48	NUM
admet-505	426	390	35	35	NUM
admet-505	426	391	0.578	0.578	NUM
admet-505	426	392	0.318	0.318	NUM
admet-505	426	393	0.0548	0.0548	NUM
admet-505	426	394	6	6	NUM
admet-505	426	395	40	40	NUM
admet-505	426	396	20	20	NUM
admet-505	426	397	0.98	0.98	NUM
admet-505	426	398	19.7	19.7	NUM
admet-505	426	399	1.56	1.56	NUM
admet-505	426	400	-1.90	-1.90	NUM
admet-505	426	401	0.20	0.20	NUM
admet-505	426	402	1	1	NUM
admet-505	426	403	0.66	0.66	NUM
admet-505	426	404	0.59	0.59	NUM
admet-505	426	405	1.56	1.56	NUM
admet-505	426	406	0.92	0.92	NUM
admet-505	426	407	1.09	1.09	NUM
admet-505	426	408	[	[	X
admet-505	426	409	31	31	NUM
admet-505	426	410	]	]	PUNCT
admet-505	426	411	benzoic	benzoic	ADJ
admet-505	426	412	acid,4	acid,4	NOUN
admet-505	426	413	-	-	PUNCT
admet-505	426	414	hoa	hoa	NOUN
admet-505	426	415	4.32	4.32	NUM
admet-505	426	416	35	35	NUM
admet-505	426	417	0.646	0.646	NUM
admet-505	426	418	0.222	0.222	NUM
admet-505	426	419	0.0161	0.0161	NUM
admet-505	426	420	6	6	NUM
admet-505	426	421	19	19	NUM
admet-505	426	422	14	14	NUM
admet-505	426	423	0.98	0.98	NUM
admet-505	426	424	13.8	13.8	NUM
admet-505	426	425	1.57	1.57	NUM
admet-505	426	426	-1.22	-1.22	NOUN
admet-505	426	427	0.10	0.10	NUM
admet-505	426	428	6	6	NUM
admet-505	426	429	1.00	1.00	NUM
admet-505	426	430	0.72	0.72	NUM
admet-505	426	431	1.29	1.29	NUM
admet-505	426	432	0.98	0.98	NUM
admet-505	426	433	0.99	0.99	NUM
admet-505	426	434	[	[	X
admet-505	426	435	31	31	NUM
admet-505	426	436	]	]	PUNCT
admet-505	426	437	benzoic	benzoic	ADJ
admet-505	426	438	acid,4	acid,4	NOUN
admet-505	426	439	-	-	PUNCT
admet-505	426	440	meoa	meoa	NOUN
admet-505	426	441	4.44	4.44	NUM
admet-505	426	442	35	35	NUM
admet-505	426	443	0.325	0.325	NUM
admet-505	426	444	0.069	0.069	NUM
admet-505	426	445	0.0040	0.0040	NUM
admet-505	426	446	6	6	NUM
admet-505	426	447	14	14	NUM
admet-505	426	448	5	5	NUM
admet-505	426	449	0.85	0.85	NUM
admet-505	426	450	4.3	4.3	NUM
admet-505	426	451	1.95	1.95	NUM
admet-505	426	452	-2.65	-2.65	NUM
admet-505	426	453	0.03	0.03	NUM
admet-505	426	454	2	2	NUM
admet-505	426	455	0.57	0.57	NUM
admet-505	426	456	0.66	0.66	NUM
admet-505	426	457	1.17	1.17	NUM
admet-505	426	458	0.81	0.81	NUM
admet-505	426	459	1.13	1.13	NUM
admet-505	426	460	[	[	X
admet-505	426	461	31	31	NUM
admet-505	426	462	]	]	PUNCT
admet-505	426	463	benzoic	benzoic	ADJ
admet-505	426	464	acid,4	acid,4	NOUN
admet-505	426	465	-	-	PUNCT
admet-505	426	466	no2a	no2a	PROPN
admet-505	426	467	3.31	3.31	NUM
admet-505	426	468	35	35	NUM
admet-505	426	469	0.290	0.290	NUM
admet-505	426	470	0.107	0.107	NUM
admet-505	426	471	0.0159	0.0159	NUM
admet-505	426	472	6	6	NUM
admet-505	426	473	20	20	NUM
admet-505	426	474	7	7	NUM
admet-505	426	475	0.95	0.95	NUM
admet-505	426	476	6.6	6.6	NUM
admet-505	426	477	1.89	1.89	NUM
admet-505	426	478	-2.62	-2.62	NUM
admet-505	426	479	0.20	0.20	NUM
admet-505	426	480	1	1	NUM
admet-505	426	481	0.66	0.66	NUM
admet-505	426	482	0.54	0.54	NUM
admet-505	426	483	1.65	1.65	NUM
admet-505	426	484	1.02	1.02	NUM
admet-505	426	485	1.11	1.11	NUM
admet-505	426	486	[	[	X
admet-505	426	487	31	31	NUM
admet-505	426	488	]	]	PUNCT
admet-505	426	489	carbamazepine	carbamazepine	NOUN
admet-505	426	490	n	n	ADP
admet-505	426	491	37	37	NUM
admet-505	426	492	0.346	0.346	NUM
admet-505	426	493	0.339	0.339	NUM
admet-505	426	494	3	3	NUM
admet-505	426	495	68	68	NUM
admet-505	426	496	22	22	NUM
admet-505	426	497	0.96	0.96	NUM
admet-505	426	498	21.0	21.0	NUM
admet-505	426	499	2.45	2.45	NUM
admet-505	426	500	-3.03	-3.03	NOUN
admet-505	426	501	0.17	0.17	NUM
admet-505	426	502	13	13	NUM
admet-505	426	503	0.39	0.39	NUM
admet-505	426	504	0.92	0.92	NUM
admet-505	426	505	2.06	2.06	NUM
admet-505	426	506	2.12	2.12	NUM
admet-505	426	507	1.81	1.81	NUM
admet-505	426	508	[	[	X
admet-505	426	509	32	32	NUM
admet-505	426	510	]	]	PUNCT
admet-505	426	511	carbamazepine	carbamazepine	NOUN
admet-505	426	512	n	n	CCONJ
admet-505	426	513	25	25	NUM
admet-505	426	514	0.312	0.312	NUM
admet-505	426	515	0.314	0.314	NUM
admet-505	426	516	0.003	0.003	NUM
admet-505	426	517	4	4	NUM
admet-505	426	518	66	66	NUM
admet-505	426	519	20	20	NUM
admet-505	426	520	0.97	0.97	NUM
admet-505	426	521	19.4	19.4	NUM
admet-505	426	522	2.45	2.45	NUM
admet-505	426	523	-3.21	-3.21	NOUN
admet-505	426	524	0.17	0.17	NUM
admet-505	426	525	13	13	NUM
admet-505	426	526	0.39	0.39	NUM
admet-505	426	527	0.92	0.92	NUM
admet-505	426	528	2.06	2.06	NUM
admet-505	426	529	2.12	2.12	NUM
admet-505	426	530	1.81	1.81	NUM
admet-505	426	531	dihydrate	dihydrate	NOUN
admet-505	426	532	[	[	X
admet-505	426	533	33	33	NUM
admet-505	426	534	]	]	PUNCT
admet-505	426	535	carbamazepine	carbamazepine	NOUN
admet-505	426	536	n	n	CCONJ
admet-505	426	537	25	25	NUM
admet-505	426	538	0.312	0.312	NUM
admet-505	426	539	0.313	0.313	NUM
admet-505	426	540	0.007	0.007	NUM
admet-505	426	541	4	4	NUM
admet-505	426	542	66	66	NUM
admet-505	426	543	20	20	NUM
admet-505	426	544	0.97	0.97	NUM
admet-505	426	545	19.4	19.4	NUM
admet-505	426	546	2.45	2.45	NUM
admet-505	426	547	-3.21	-3.21	NOUN
admet-505	426	548	0.17	0.17	NUM
admet-505	426	549	13	13	NUM
admet-505	426	550	0.39	0.39	NUM
admet-505	426	551	0.92	0.92	NUM
admet-505	426	552	2.06	2.06	NUM
admet-505	426	553	2.12	2.12	NUM
admet-505	426	554	1.81	1.81	NUM
admet-505	426	555	cc	cc	NOUN
admet-505	426	556	(	(	PUNCT
admet-505	426	557	nicrotinamide	nicrotinamide	NOUN
admet-505	426	558	)	)	PUNCT
admet-505	427	1	[	[	X
admet-505	427	2	33	33	NUM
admet-505	427	3	]	]	PUNCT
admet-505	427	4	carbamazepine	carbamazepine	NOUN
admet-505	427	5	n	n	CCONJ
admet-505	427	6	25	25	NUM
admet-505	427	7	0.312	0.312	NUM
admet-505	427	8	0.309	0.309	NUM
admet-505	427	9	0.025	0.025	NUM
admet-505	427	10	4	4	NUM
admet-505	427	11	66	66	NUM
admet-505	427	12	20	20	NUM
admet-505	427	13	0.96	0.96	NUM
admet-505	427	14	19.2	19.2	NUM
admet-505	427	15	2.45	2.45	NUM
admet-505	427	16	-3.21	-3.21	NOUN
admet-505	427	17	0.17	0.17	NUM
admet-505	427	18	13	13	NUM
admet-505	427	19	0.39	0.39	NUM
admet-505	427	20	0.92	0.92	NUM
admet-505	427	21	2.06	2.06	NUM
admet-505	427	22	2.12	2.12	NUM
admet-505	427	23	1.81	1.81	NUM
admet-505	427	24	cc	cc	NOUN
admet-505	427	25	(	(	PUNCT
admet-505	427	26	mixture	mixture	NOUN
admet-505	427	27	)	)	PUNCT
admet-505	428	1	[	[	X
admet-505	428	2	33	33	NUM
admet-505	428	3	]	]	PUNCT
admet-505	428	4	carbamazepine	carbamazepine	NOUN
admet-505	428	5	n	n	CCONJ
admet-505	428	6	25	25	NUM
admet-505	428	7	0.312	0.312	NUM
admet-505	428	8	0.298	0.298	NUM
admet-505	428	9	0.007	0.007	NUM
admet-505	428	10	11	11	NUM
admet-505	428	11	63	63	NUM
admet-505	428	12	19	19	NUM
admet-505	428	13	0.97	0.97	NUM
admet-505	428	14	18.5	18.5	NUM
admet-505	428	15	2.45	2.45	NUM
admet-505	428	16	-3.21	-3.21	NOUN
admet-505	428	17	0.17	0.17	NUM
admet-505	428	18	13	13	NUM
admet-505	428	19	0.39	0.39	NUM
admet-505	428	20	0.92	0.92	NUM
admet-505	428	21	2.06	2.06	NUM
admet-505	428	22	2.12	2.12	NUM
admet-505	428	23	1.81	1.81	NUM
admet-505	428	24	cc	cc	NOUN
admet-505	428	25	(	(	PUNCT
admet-505	428	26	4	4	NUM
admet-505	428	27	-	-	PUNCT
admet-505	428	28	nh2	nh2	NOUN
admet-505	428	29	-	-	PUNCT
admet-505	428	30	benzoic	benzoic	NOUN
admet-505	428	31	acid	acid	NOUN
admet-505	428	32	)	)	PUNCT
admet-505	428	33	,	,	PUNCT
admet-505	428	34	ph	ph	VERB
admet-505	428	35	4.0	4.0	NUM
admet-505	428	36	[	[	SYM
admet-505	428	37	6	6	NUM
admet-505	428	38	]	]	PUNCT
admet-505	428	39	carbamazepine	carbamazepine	NOUN
admet-505	428	40	n	n	CCONJ
admet-505	428	41	25	25	NUM
admet-505	428	42	0.312	0.312	NUM
admet-505	428	43	0.348	0.348	NUM
admet-505	428	44	0.017	0.017	NUM
admet-505	428	45	7	7	NUM
admet-505	428	46	72	72	NUM
admet-505	428	47	22	22	NUM
admet-505	428	48	0.98	0.98	NUM
admet-505	428	49	21.6	21.6	NUM
admet-505	428	50	2.45	2.45	NUM
admet-505	428	51	-3.21	-3.21	NOUN
admet-505	428	52	0.17	0.17	NUM
admet-505	428	53	13	13	NUM
admet-505	428	54	0.39	0.39	NUM
admet-505	428	55	0.92	0.92	NUM
admet-505	428	56	2.06	2.06	NUM
admet-505	428	57	2.12	2.12	NUM
admet-505	428	58	1.81	1.81	NUM
admet-505	428	59	cc	cc	NOUN
admet-505	428	60	(	(	PUNCT
admet-505	428	61	saccharin	saccharin	NOUN
admet-505	428	62	)	)	PUNCT
admet-505	428	63	,	,	PUNCT
admet-505	428	64	ph	ph	VERB
admet-505	428	65	2.2	2.2	NUM
admet-505	428	66	[	[	SYM
admet-505	428	67	6	6	NUM
admet-505	428	68	]	]	PUNCT
admet-505	428	69	alex	alex	PROPN
admet-505	428	70	avdeef	avdeef	PROPN
admet-505	428	71	admet	admet	PROPN
admet-505	428	72	&	&	CCONJ
admet-505	428	73	dmpk	dmpk	PROPN
admet-505	428	74	6(2	6(2	NUM
admet-505	428	75	)	)	PUNCT
admet-505	428	76	(	(	PUNCT
admet-505	428	77	2018	2018	NUM
admet-505	428	78	)	)	PUNCT
admet-505	428	79	105	105	NUM
admet-505	428	80	-	-	SYM
admet-505	428	81	139	139	NUM
admet-505	428	82	114	114	NUM
admet-505	428	83	table	table	NOUN
admet-505	428	84	1	1	NUM
admet-505	428	85	.	.	NUM
admet-505	428	86	continued	continue	VERB
admet-505	428	87	…	…	PUNCT
admet-505	428	88	compound	compound	NOUN
admet-505	428	89	type	type	NOUN
admet-505	428	90	pka	pka	PROPN
admet-505	428	91	(	(	PUNCT
admet-505	428	92	acid	acid	PROPN
admet-505	428	93	)	)	PUNCT
admet-505	428	94	pka	pka	PROPN
admet-505	428	95	(	(	PUNCT
admet-505	428	96	base	base	NOUN
admet-505	428	97	)	)	PUNCT
admet-505	428	98	t(`c	t(`c	PROPN
admet-505	428	99	)	)	PUNCT
admet-505	429	1	k	k	PROPN
admet-505	429	2	(	(	PUNCT
admet-505	429	3	calc	calc	NOUN
admet-505	429	4	)	)	PUNCT
admet-505	429	5	b	b	PROPN
admet-505	430	1	k	k	PROPN
admet-505	430	2	(	(	PUNCT
admet-505	430	3	obs	obs	PROPN
admet-505	430	4	)	)	PUNCT
admet-505	430	5	c	c	PROPN
admet-505	430	6	±	±	NUM
admet-505	430	7	sd	sd	ADP
admet-505	430	8	n	n	PROPN
admet-505	430	9	d	d	NOUN
admet-505	430	10	log	log	NOUN
admet-505	430	11	kn	kn	PROPN
admet-505	430	12	e	e	PROPN
admet-505	430	13	n	n	PROPN
admet-505	430	14	fbm	fbm	NOUN
admet-505	430	15	nd	nd	PRON
admet-505	430	16	log	log	VERB
admet-505	430	17	poct	poct	PROPN
admet-505	430	18	log	log	NOUN
admet-505	430	19	s0	s0	PROPN
admet-505	430	20	±sd	±sd	PROPN
admet-505	430	21	n	n	CCONJ
admet-505	430	22	σα2	σα2	NOUN
admet-505	430	23	h	h	NOUN
admet-505	430	24	σβ2	σβ2	VERB
admet-505	430	25	h	h	PROPN
admet-505	430	26	π2	π2	PROPN
admet-505	430	27	r2	r2	PROPN
admet-505	430	28	vx	vx	PROPN
admet-505	430	29	comments	comment	NOUN
admet-505	430	30	ref	ref	NOUN
admet-505	430	31	carbamazepine	carbamazepine	NOUN
admet-505	430	32	n	n	ADP
admet-505	430	33	25	25	NUM
admet-505	430	34	0.312	0.312	NUM
admet-505	430	35	0.334	0.334	NUM
admet-505	430	36	0.055	0.055	NUM
admet-505	430	37	5	5	NUM
admet-505	430	38	69	69	NUM
admet-505	430	39	21	21	NUM
admet-505	430	40	0.99	0.99	NUM
admet-505	430	41	20.7	20.7	NUM
admet-505	430	42	2.45	2.45	NUM
admet-505	430	43	-3.21	-3.21	NOUN
admet-505	430	44	0.17	0.17	NUM
admet-505	430	45	13	13	NUM
admet-505	430	46	0.39	0.39	NUM
admet-505	430	47	0.92	0.92	NUM
admet-505	430	48	2.06	2.06	NUM
admet-505	430	49	2.12	2.12	NUM
admet-505	430	50	1.81	1.81	NUM
admet-505	430	51	cc	cc	NOUN
admet-505	430	52	(	(	PUNCT
admet-505	430	53	salicylic	salicylic	ADJ
admet-505	430	54	acid	acid	NOUN
admet-505	430	55	)	)	PUNCT
admet-505	430	56	,	,	PUNCT
admet-505	430	57	ph	ph	VERB
admet-505	430	58	3.0	3.0	NUM
admet-505	430	59	[	[	SYM
admet-505	430	60	6	6	NUM
admet-505	430	61	]	]	PUNCT
admet-505	430	62	carbamazepine	carbamazepine	NOUN
admet-505	430	63	n	n	CCONJ
admet-505	430	64	25	25	NUM
admet-505	430	65	0.312	0.312	NUM
admet-505	430	66	0.297	0.297	NUM
admet-505	430	67	0.007	0.007	NUM
admet-505	430	68	10	10	NUM
admet-505	430	69	63	63	NUM
admet-505	430	70	19	19	NUM
admet-505	430	71	0.97	0.97	NUM
admet-505	430	72	18.4	18.4	NUM
admet-505	430	73	2.45	2.45	NUM
admet-505	430	74	-3.21	-3.21	NOUN
admet-505	430	75	0.17	0.17	NUM
admet-505	430	76	13	13	NUM
admet-505	430	77	0.39	0.39	NUM
admet-505	430	78	0.92	0.92	NUM
admet-505	430	79	2.06	2.06	NUM
admet-505	430	80	2.12	2.12	NUM
admet-505	430	81	1.81	1.81	NUM
admet-505	430	82	cc	cc	NOUN
admet-505	430	83	(	(	PUNCT
admet-505	430	84	succinic	succinic	ADJ
admet-505	430	85	acid	acid	NOUN
admet-505	430	86	)	)	PUNCT
admet-505	430	87	,	,	PUNCT
admet-505	430	88	ph	ph	VERB
admet-505	430	89	3.1	3.1	NUM
admet-505	430	90	[	[	SYM
admet-505	430	91	6	6	NUM
admet-505	430	92	]	]	X
admet-505	430	93	carbendazim	carbendazim	NOUN
admet-505	430	94	ab	ab	PROPN
admet-505	430	95	10.52	10.52	NUM
admet-505	430	96	4.48	4.48	NUM
admet-505	430	97	23	23	NUM
admet-505	430	98	0.092	0.092	NUM
admet-505	430	99	0.079	0.079	NUM
admet-505	430	100	0.012	0.012	NUM
admet-505	430	101	4	4	NUM
admet-505	430	102	24	24	NUM
admet-505	430	103	5	5	NUM
admet-505	430	104	0.98	0.98	NUM
admet-505	430	105	4.9	4.9	NUM
admet-505	430	106	1.52	1.52	NUM
admet-505	430	107	-4.47	-4.47	NUM
admet-505	430	108	0.03	0.03	NUM
admet-505	430	109	3	3	NUM
admet-505	430	110	0.71	0.71	NUM
admet-505	430	111	0.99	0.99	NUM
admet-505	430	112	1.86	1.86	NUM
admet-505	430	113	1.64	1.64	NUM
admet-505	430	114	1.36	1.36	NUM
admet-505	431	1	[	[	X
admet-505	431	2	34	34	NUM
admet-505	431	3	]	]	X
admet-505	431	4	carvedilol	carvedilol	PROPN
admet-505	431	5	b	b	PROPN
admet-505	431	6	7.75	7.75	NUM
admet-505	431	7	37	37	NUM
admet-505	431	8	0.020	0.020	NUM
admet-505	431	9	0.051	0.051	NUM
admet-505	431	10	0.001	0.001	NUM
admet-505	431	11	5	5	NUM
admet-505	431	12	22	22	NUM
admet-505	431	13	4	4	NUM
admet-505	431	14	0.79	0.79	NUM
admet-505	431	15	3.2	3.2	NUM
admet-505	431	16	4.14	4.14	NUM
admet-505	431	17	-5.40	-5.40	NUM
admet-505	431	18	0.36	0.36	NUM
admet-505	431	19	7	7	NUM
admet-505	431	20	0.62	0.62	NUM
admet-505	431	21	2.09	2.09	NUM
admet-505	431	22	3.00	3.00	NUM
admet-505	431	23	3.08	3.08	NUM
admet-505	431	24	3.10	3.10	NUM
admet-505	431	25	ph	ph	NOUN
admet-505	431	26	1.2	1.2	NUM
admet-505	431	27	[	[	SYM
admet-505	431	28	35	35	NUM
admet-505	431	29	]	]	X
admet-505	431	30	carvedilol	carvedilol	PROPN
admet-505	431	31	b	b	PROPN
admet-505	431	32	7.75	7.75	NUM
admet-505	431	33	37	37	NUM
admet-505	431	34	0.020	0.020	NUM
admet-505	431	35	0.061	0.061	NUM
admet-505	431	36	0.002	0.002	NUM
admet-505	431	37	5	5	NUM
admet-505	431	38	23	23	NUM
admet-505	431	39	4	4	NUM
admet-505	431	40	0.94	0.94	NUM
admet-505	431	41	3.8	3.8	NUM
admet-505	431	42	4.14	4.14	NUM
admet-505	431	43	-5.40	-5.40	NUM
admet-505	431	44	0.36	0.36	NUM
admet-505	431	45	7	7	NUM
admet-505	431	46	0.62	0.62	NUM
admet-505	431	47	2.09	2.09	NUM
admet-505	431	48	3.00	3.00	NUM
admet-505	431	49	3.08	3.08	NUM
admet-505	431	50	3.10	3.10	NUM
admet-505	431	51	ph	ph	NOUN
admet-505	431	52	3.0	3.0	NUM
admet-505	431	53	[	[	SYM
admet-505	431	54	35	35	NUM
admet-505	431	55	]	]	X
admet-505	431	56	carvedilol	carvedilol	PROPN
admet-505	431	57	b	b	PROPN
admet-505	431	58	7.75	7.75	NUM
admet-505	431	59	37	37	NUM
admet-505	431	60	0.020	0.020	NUM
admet-505	431	61	0.064	0.064	NUM
admet-505	431	62	0.005	0.005	NUM
admet-505	431	63	5	5	NUM
admet-505	431	64	23	23	NUM
admet-505	431	65	4	4	NUM
admet-505	431	66	0.99	0.99	NUM
admet-505	431	67	3.9	3.9	NUM
admet-505	431	68	4.14	4.14	NUM
admet-505	431	69	-5.40	-5.40	NUM
admet-505	431	70	0.36	0.36	NUM
admet-505	431	71	7	7	NUM
admet-505	431	72	0.62	0.62	NUM
admet-505	431	73	2.09	2.09	NUM
admet-505	431	74	3.00	3.00	NUM
admet-505	431	75	3.08	3.08	NUM
admet-505	431	76	3.10	3.10	NUM
admet-505	431	77	ph	ph	NOUN
admet-505	431	78	4.5	4.5	NUM
admet-505	431	79	[	[	SYM
admet-505	431	80	35	35	NUM
admet-505	431	81	]	]	X
admet-505	431	82	carvedilol	carvedilol	PROPN
admet-505	431	83	b	b	PROPN
admet-505	431	84	7.75	7.75	NUM
admet-505	431	85	37	37	NUM
admet-505	431	86	0.020	0.020	NUM
admet-505	431	87	0.061	0.061	NUM
admet-505	431	88	0.006	0.006	NUM
admet-505	431	89	5	5	NUM
admet-505	431	90	23	23	NUM
admet-505	431	91	4	4	NUM
admet-505	431	92	0.94	0.94	NUM
admet-505	431	93	3.8	3.8	NUM
admet-505	431	94	4.14	4.14	NUM
admet-505	431	95	-5.40	-5.40	NUM
admet-505	431	96	0.36	0.36	NUM
admet-505	431	97	7	7	NUM
admet-505	431	98	0.62	0.62	NUM
admet-505	431	99	2.09	2.09	NUM
admet-505	431	100	3.00	3.00	NUM
admet-505	431	101	3.08	3.08	NUM
admet-505	431	102	3.10	3.10	NUM
admet-505	431	103	ph	ph	NOUN
admet-505	431	104	5.8	5.8	NUM
admet-505	431	105	[	[	NOUN
admet-505	431	106	35	35	NUM
admet-505	431	107	]	]	X
admet-505	431	108	carvedilol	carvedilol	PROPN
admet-505	431	109	b	b	PROPN
admet-505	431	110	7.75	7.75	NUM
admet-505	431	111	37	37	NUM
admet-505	431	112	0.020	0.020	NUM
admet-505	431	113	0.063	0.063	NUM
admet-505	431	114	5	5	NUM
admet-505	431	115	23	23	NUM
admet-505	431	116	4	4	NUM
admet-505	431	117	0.98	0.98	NUM
admet-505	431	118	3.9	3.9	NUM
admet-505	431	119	4.14	4.14	NUM
admet-505	431	120	-5.40	-5.40	NUM
admet-505	431	121	0.36	0.36	NUM
admet-505	431	122	7	7	NUM
admet-505	431	123	0.62	0.62	NUM
admet-505	431	124	2.09	2.09	NUM
admet-505	431	125	3.00	3.00	NUM
admet-505	431	126	3.08	3.08	NUM
admet-505	431	127	3.10	3.10	NUM
admet-505	431	128	ph	ph	NOUN
admet-505	431	129	6.8	6.8	NUM
admet-505	431	130	[	[	SYM
admet-505	431	131	35	35	NUM
admet-505	431	132	]	]	X
admet-505	431	133	carvedilol	carvedilol	PROPN
admet-505	431	134	b	b	PROPN
admet-505	431	135	7.75	7.75	NUM
admet-505	431	136	37	37	NUM
admet-505	431	137	0.020	0.020	NUM
admet-505	431	138	0.061	0.061	NUM
admet-505	431	139	0.001	0.001	NUM
admet-505	431	140	5	5	NUM
admet-505	431	141	23	23	NUM
admet-505	431	142	4	4	NUM
admet-505	431	143	0.94	0.94	NUM
admet-505	431	144	3.8	3.8	NUM
admet-505	431	145	4.14	4.14	NUM
admet-505	431	146	-5.40	-5.40	NUM
admet-505	431	147	0.36	0.36	NUM
admet-505	431	148	7	7	NUM
admet-505	431	149	0.62	0.62	NUM
admet-505	431	150	2.09	2.09	NUM
admet-505	431	151	3.00	3.00	NUM
admet-505	431	152	3.08	3.08	NUM
admet-505	431	153	3.10	3.10	NUM
admet-505	431	154	ph	ph	NOUN
admet-505	431	155	7.2	7.2	NUM
admet-505	431	156	[	[	SYM
admet-505	431	157	35	35	NUM
admet-505	431	158	]	]	PUNCT
admet-505	431	159	clofazimine	clofazimine	PROPN
admet-505	431	160	b	b	PROPN
admet-505	431	161	8.51	8.51	NUM
admet-505	431	162	37	37	NUM
admet-505	431	163	0.0012	0.0012	NUM
admet-505	431	164	0.0006	0.0006	NUM
admet-505	431	165	6.2	6.2	NUM
admet-505	431	166	1	1	NUM
admet-505	431	167	0.03	0.03	NUM
admet-505	431	168	9	9	NUM
admet-505	431	169	0.03	0.03	NUM
admet-505	431	170	9	9	NUM
admet-505	431	171	4.40	4.40	NUM
admet-505	431	172	-7.63	-7.63	NUM
admet-505	431	173	0.02	0.02	NUM
admet-505	431	174	1	1	NUM
admet-505	431	175	0.19	0.19	NUM
admet-505	431	176	1.28	1.28	NUM
admet-505	431	177	2.34	2.34	NUM
admet-505	431	178	3.50	3.50	NUM
admet-505	431	179	3.45	3.45	NUM
admet-505	431	180	[	[	SYM
admet-505	431	181	30	30	NUM
admet-505	431	182	]	]	PUNCT
admet-505	431	183	curcumin	curcumin	NOUN
admet-505	431	184	a	a	DET
admet-505	431	185	10.51	10.51	NUM
admet-505	431	186	9.88	9.88	NUM
admet-505	431	187	8.37	8.37	NUM
admet-505	431	188	22	22	NUM
admet-505	431	189	0.003	0.003	NUM
admet-505	431	190	0.027	0.027	NUM
admet-505	431	191	0.001	0.001	NUM
admet-505	431	192	9	9	NUM
admet-505	431	193	16	16	NUM
admet-505	431	194	2	2	NUM
admet-505	431	195	0.82	0.82	NUM
admet-505	431	196	1.6	1.6	NUM
admet-505	431	197	2.85	2.85	NUM
admet-505	431	198	-7.52	-7.52	NUM
admet-505	431	199	0.20	0.20	NUM
admet-505	431	200	1	1	NUM
admet-505	431	201	0.55	0.55	NUM
admet-505	431	202	1.67	1.67	NUM
admet-505	431	203	2.85	2.85	NUM
admet-505	431	204	2.30	2.30	NUM
admet-505	431	205	2.77	2.77	NUM
admet-505	431	206	[	[	X
admet-505	431	207	28	28	NUM
admet-505	431	208	]	]	X
admet-505	431	209	diazepam	diazepam	VERB
admet-505	431	210	b	b	PROPN
admet-505	431	211	3.41	3.41	NUM
admet-505	431	212	24	24	NUM
admet-505	431	213	0.146	0.146	NUM
admet-505	431	214	0.349	0.349	NUM
admet-505	431	215	0.014	0.014	NUM
admet-505	431	216	3	3	NUM
admet-505	431	217	85	85	NUM
admet-505	431	218	22	22	NUM
admet-505	431	219	0.98	0.98	NUM
admet-505	431	220	21.6	21.6	NUM
admet-505	431	221	2.99	2.99	NUM
admet-505	431	222	-3.81	-3.81	NUM
admet-505	431	223	0.11	0.11	NUM
admet-505	431	224	10	10	NUM
admet-505	431	225	0.00	0.00	NUM
admet-505	431	226	1.04	1.04	NUM
admet-505	431	227	1.72	1.72	NUM
admet-505	431	228	2.11	2.11	NUM
admet-505	431	229	2.07	2.07	NUM
admet-505	431	230	[	[	X
admet-505	431	231	36	36	NUM
admet-505	431	232	]	]	X
admet-505	431	233	diazepam	diazepam	VERB
admet-505	431	234	b	b	PROPN
admet-505	431	235	3.41	3.41	NUM
admet-505	431	236	24	24	NUM
admet-505	431	237	0.146	0.146	NUM
admet-505	431	238	0.261	0.261	NUM
admet-505	431	239	0.003	0.003	NUM
admet-505	431	240	3	3	NUM
admet-505	431	241	66	66	NUM
admet-505	431	242	17	17	NUM
admet-505	431	243	0.95	0.95	NUM
admet-505	431	244	16.2	16.2	NUM
admet-505	431	245	2.99	2.99	NUM
admet-505	431	246	-3.81	-3.81	NUM
admet-505	431	247	0.11	0.11	NUM
admet-505	431	248	10	10	NUM
admet-505	431	249	0.00	0.00	NUM
admet-505	431	250	1.04	1.04	NUM
admet-505	431	251	1.72	1.72	NUM
admet-505	431	252	2.11	2.11	NUM
admet-505	431	253	2.07	2.07	NUM
admet-505	431	254	0.15	0.15	NUM
admet-505	431	255	m	m	NOUN
admet-505	431	256	nacl	nacl	NOUN
admet-505	431	257	[	[	X
admet-505	431	258	36	36	NUM
admet-505	431	259	]	]	PUNCT
admet-505	431	260	erythromycin	erythromycin	VERB
admet-505	431	261	b	b	NOUN
admet-505	431	262	8.82	8.82	NUM
admet-505	431	263	25	25	NUM
admet-505	431	264	0.546	0.546	NUM
admet-505	431	265	0.345	0.345	NUM
admet-505	431	266	0.117	0.117	NUM
admet-505	431	267	4	4	NUM
admet-505	431	268	62	62	NUM
admet-505	431	269	22	22	NUM
admet-505	431	270	0.97	0.97	NUM
admet-505	431	271	21.4	21.4	NUM
admet-505	431	272	2.54	2.54	NUM
admet-505	431	273	-2.75	-2.75	NUM
admet-505	431	274	0.26	0.26	NUM
admet-505	431	275	4	4	NUM
admet-505	431	276	1.05	1.05	NUM
admet-505	431	277	4.63	4.63	NUM
admet-505	431	278	3.04	3.04	NUM
admet-505	431	279	2.51	2.51	NUM
admet-505	431	280	5.77	5.77	NUM
admet-505	431	281	[	[	X
admet-505	431	282	37	37	NUM
admet-505	431	283	]	]	PUNCT
admet-505	431	284	estradiol,17βa	estradiol,17βa	NOUN
admet-505	431	285	4.25	4.25	NUM
admet-505	431	286	24	24	NUM
admet-505	431	287	0.029	0.029	NUM
admet-505	431	288	0.022	0.022	NUM
admet-505	431	289	0.002	0.002	NUM
admet-505	431	290	3	3	NUM
admet-505	431	291	10	10	NUM
admet-505	431	292	2	2	NUM
admet-505	431	293	0.69	0.69	NUM
admet-505	431	294	1.4	1.4	NUM
admet-505	431	295	3.86	3.86	NUM
admet-505	431	296	-4.90	-4.90	NUM
admet-505	431	297	0.18	0.18	NUM
admet-505	431	298	4	4	NUM
admet-505	431	299	0.81	0.81	NUM
admet-505	431	300	0.95	0.95	NUM
admet-505	431	301	2.30	2.30	NUM
admet-505	431	302	1.85	1.85	NUM
admet-505	431	303	2.20	2.20	NUM
admet-505	431	304	[	[	X
admet-505	431	305	36	36	NUM
admet-505	431	306	]	]	PUNCT
admet-505	431	307	fenofibrate	fenofibrate	NOUN
admet-505	431	308	n	n	CCONJ
admet-505	432	1	25	25	NUM
admet-505	432	2	0.061	0.061	NUM
admet-505	432	3	0.035	0.035	NUM
admet-505	432	4	0.008	0.008	NUM
admet-505	432	5	4	4	NUM
admet-505	432	6	18	18	NUM
admet-505	432	7	3	3	NUM
admet-505	432	8	0.72	0.72	NUM
admet-505	432	9	2.2	2.2	NUM
admet-505	432	10	5.23	5.23	NUM
admet-505	432	11	-5.90	-5.90	NUM
admet-505	432	12	0.32	0.32	NUM
admet-505	432	13	5	5	NUM
admet-505	432	14	0.00	0.00	NUM
admet-505	432	15	1.13	1.13	NUM
admet-505	432	16	2.11	2.11	NUM
admet-505	432	17	1.62	1.62	NUM
admet-505	432	18	2.72	2.72	NUM
admet-505	433	1	[	[	PUNCT
admet-505	433	2	38	38	NUM
admet-505	433	3	]	]	PUNCT
admet-505	433	4	glibenclamide	glibenclamide	ADP
admet-505	433	5	a	a	DET
admet-505	433	6	5.30	5.30	NUM
admet-505	433	7	25	25	NUM
admet-505	433	8	0.0065	0.0065	NUM
admet-505	433	9	0.00047	0.00047	NUM
admet-505	433	10	0.0002	0.0002	NUM
admet-505	433	11	1	1	NUM
admet-505	433	12	5.0	5.0	NUM
admet-505	433	13	1	1	NUM
admet-505	433	14	0.02	0.02	NUM
admet-505	433	15	9	9	NUM
admet-505	433	16	0.02	0.02	NUM
admet-505	433	17	9	9	NUM
admet-505	433	18	3.75	3.75	NUM
admet-505	433	19	-6.54	-6.54	NUM
admet-505	433	20	0.44	0.44	NUM
admet-505	433	21	10	10	NUM
admet-505	433	22	0.85	0.85	NUM
admet-505	433	23	2.01	2.01	NUM
admet-505	433	24	3.84	3.84	NUM
admet-505	433	25	2.64	2.64	NUM
admet-505	433	26	3.47	3.47	NUM
admet-505	433	27	[	[	X
admet-505	433	28	39	39	NUM
admet-505	433	29	]	]	PUNCT
admet-505	433	30	glibenclamide	glibenclamide	ADP
admet-505	433	31	a	a	DET
admet-505	433	32	5.30	5.30	NUM
admet-505	433	33	25	25	NUM
admet-505	433	34	0.0065	0.0065	NUM
admet-505	433	35	0.00089	0.00089	NUM
admet-505	434	1	0.001	0.001	NUM
admet-505	434	2	1	1	NUM
admet-505	434	3	5.3	5.3	NUM
admet-505	434	4	1	1	NUM
admet-505	434	5	0.05	0.05	NUM
admet-505	434	6	5	5	NUM
admet-505	434	7	0.05	0.05	NUM
admet-505	434	8	5	5	NUM
admet-505	434	9	3.75	3.75	NUM
admet-505	434	10	-6.54	-6.54	NUM
admet-505	434	11	0.44	0.44	NUM
admet-505	434	12	10	10	NUM
admet-505	434	13	0.85	0.85	NUM
admet-505	434	14	2.01	2.01	NUM
admet-505	434	15	3.84	3.84	NUM
admet-505	434	16	2.64	2.64	NUM
admet-505	434	17	3.47	3.47	NUM
admet-505	434	18	0.15	0.15	NUM
admet-505	434	19	m	m	NOUN
admet-505	434	20	nacl	nacl	NOUN
admet-505	434	21	[	[	X
admet-505	434	22	39	39	NUM
admet-505	434	23	]	]	PUNCT
admet-505	434	24	gliclazide	gliclazide	NOUN
admet-505	434	25	a	a	DET
admet-505	434	26	5.49	5.49	NUM
admet-505	434	27	25	25	NUM
admet-505	434	28	0.048	0.048	NUM
admet-505	434	29	0.036	0.036	NUM
admet-505	434	30	0.034	0.034	NUM
admet-505	434	31	1	1	NUM
admet-505	434	32	14	14	NUM
admet-505	434	33	3	3	NUM
admet-505	434	34	0.74	0.74	NUM
admet-505	434	35	2.2	2.2	NUM
admet-505	434	36	1.51	1.51	NUM
admet-505	434	37	-4.35	-4.35	NUM
admet-505	434	38	0.32	0.32	NUM
admet-505	434	39	5	5	NUM
admet-505	434	40	0.59	0.59	NUM
admet-505	434	41	1.66	1.66	NUM
admet-505	434	42	2.54	2.54	NUM
admet-505	434	43	1.93	1.93	NUM
admet-505	434	44	2.28	2.28	NUM
admet-505	435	1	[	[	X
admet-505	435	2	39	39	NUM
admet-505	435	3	]	]	PUNCT
admet-505	435	4	gliclazide	gliclazide	NOUN
admet-505	435	5	a	a	DET
admet-505	435	6	5.49	5.49	NUM
admet-505	435	7	25	25	NUM
admet-505	435	8	0.048	0.048	NUM
admet-505	435	9	0.049	0.049	NUM
admet-505	435	10	0.042	0.042	NUM
admet-505	435	11	1	1	NUM
admet-505	435	12	18	18	NUM
admet-505	435	13	4	4	NUM
admet-505	435	14	0.76	0.76	NUM
admet-505	435	15	3.1	3.1	NUM
admet-505	435	16	1.51	1.51	NUM
admet-505	435	17	-4.35	-4.35	NUM
admet-505	435	18	0.32	0.32	NUM
admet-505	435	19	5	5	NUM
admet-505	435	20	0.59	0.59	NUM
admet-505	435	21	1.66	1.66	NUM
admet-505	435	22	2.54	2.54	NUM
admet-505	435	23	1.93	1.93	NUM
admet-505	435	24	2.28	2.28	NUM
admet-505	435	25	0.15	0.15	NUM
admet-505	435	26	m	m	NOUN
admet-505	435	27	nacl	nacl	NOUN
admet-505	435	28	[	[	X
admet-505	435	29	39	39	NUM
admet-505	435	30	]	]	PUNCT
admet-505	435	31	glimepiride	glimepiride	NOUN
admet-505	435	32	a	a	DET
admet-505	435	33	5.62	5.62	NUM
admet-505	435	34	25	25	NUM
admet-505	435	35	0.004	0.004	NUM
admet-505	435	36	0.010	0.010	NUM
admet-505	435	37	0.010	0.010	NUM
admet-505	435	38	1	1	NUM
admet-505	435	39	7.4	7.4	NUM
admet-505	435	40	1	1	NUM
admet-505	435	41	0.65	0.65	NUM
admet-505	435	42	0.6	0.6	NUM
admet-505	435	43	2.94	2.94	NUM
admet-505	435	44	-7.09	-7.09	NUM
admet-505	435	45	0.57	0.57	NUM
admet-505	435	46	6	6	NUM
admet-505	435	47	0.75	0.75	NUM
admet-505	435	48	2.15	2.15	NUM
admet-505	435	49	3.50	3.50	NUM
admet-505	435	50	2.41	2.41	NUM
admet-505	435	51	3.63	3.63	NUM
admet-505	436	1	[	[	X
admet-505	436	2	39	39	NUM
admet-505	436	3	]	]	PUNCT
admet-505	436	4	glimepiride	glimepiride	NOUN
admet-505	436	5	a	a	DET
admet-505	436	6	5.62	5.62	NUM
admet-505	436	7	25	25	NUM
admet-505	436	8	0.004	0.004	NUM
admet-505	436	9	0.020	0.020	NUM
admet-505	436	10	0.020	0.020	NUM
admet-505	436	11	1	1	NUM
admet-505	436	12	14	14	NUM
admet-505	436	13	2	2	NUM
admet-505	436	14	0.63	0.63	NUM
admet-505	436	15	1.3	1.3	NUM
admet-505	436	16	2.94	2.94	NUM
admet-505	436	17	-7.09	-7.09	NUM
admet-505	436	18	0.57	0.57	NUM
admet-505	436	19	6	6	NUM
admet-505	436	20	0.75	0.75	NUM
admet-505	436	21	2.15	2.15	NUM
admet-505	436	22	3.50	3.50	NUM
admet-505	436	23	2.41	2.41	NUM
admet-505	436	24	3.63	3.63	NUM
admet-505	436	25	0.15	0.15	NUM
admet-505	436	26	m	m	NOUN
admet-505	436	27	nacl	nacl	NOUN
admet-505	436	28	[	[	X
admet-505	436	29	39	39	NUM
admet-505	436	30	]	]	PUNCT
admet-505	436	31	glipizide	glipizide	NOUN
admet-505	436	32	a	a	DET
admet-505	436	33	5.13	5.13	NUM
admet-505	436	34	25	25	NUM
admet-505	436	35	0.016	0.016	NUM
admet-505	436	36	0.011	0.011	NUM
admet-505	436	37	0.010	0.010	NUM
admet-505	436	38	1	1	NUM
admet-505	436	39	5.8	5.8	NUM
admet-505	436	40	1	1	NUM
admet-505	436	41	0.66	0.66	NUM
admet-505	436	42	0.7	0.7	NUM
admet-505	436	43	2.01	2.01	NUM
admet-505	436	44	-5.53	-5.53	NOUN
admet-505	436	45	0.17	0.17	NUM
admet-505	436	46	6	6	NUM
admet-505	436	47	0.85	0.85	NUM
admet-505	436	48	2.19	2.19	NUM
admet-505	436	49	3.71	3.71	NUM
admet-505	436	50	2.52	2.52	NUM
admet-505	436	51	3.21	3.21	NUM
admet-505	437	1	[	[	X
admet-505	437	2	39	39	NUM
admet-505	437	3	]	]	PUNCT
admet-505	437	4	admet	admet	PROPN
admet-505	437	5	&	&	CCONJ
admet-505	437	6	dmpk	dmpk	PROPN
admet-505	437	7	6(2	6(2	NUM
admet-505	437	8	)	)	PUNCT
admet-505	438	1	(	(	PUNCT
admet-505	438	2	2018	2018	NUM
admet-505	438	3	)	)	PUNCT
admet-505	438	4	105	105	NUM
admet-505	438	5	-	-	SYM
admet-505	438	6	139	139	NUM
admet-505	438	7	cocrystal	cocrystal	ADJ
admet-505	438	8	solubility	solubility	NOUN
admet-505	438	9	-	-	PUNCT
admet-505	438	10	ph	ph	VERB
admet-505	438	11	,	,	PUNCT
admet-505	438	12	drug	drug	NOUN
admet-505	438	13	solubilization	solubilization	NOUN
admet-505	438	14	capacity	capacity	NOUN
admet-505	438	15	of	of	ADP
admet-505	438	16	sds	sds	PROPN
admet-505	438	17	,	,	PUNCT
admet-505	438	18	mass	mass	ADJ
admet-505	438	19	action	action	NOUN
admet-505	438	20	model	model	NOUN
admet-505	438	21	doi	doi	PROPN
admet-505	438	22	:	:	PUNCT
admet-505	438	23	10.5599	10.5599	NUM
admet-505	438	24	/	/	SYM
admet-505	438	25	admet.505	admet.505	PROPN
admet-505	438	26	115	115	NUM
admet-505	438	27	table	table	NOUN
admet-505	438	28	1	1	NUM
admet-505	438	29	.	.	NUM
admet-505	438	30	continued	continue	VERB
admet-505	438	31	…	…	PUNCT
admet-505	438	32	compound	compound	NOUN
admet-505	438	33	type	type	NOUN
admet-505	438	34	pka	pka	PROPN
admet-505	438	35	(	(	PUNCT
admet-505	438	36	acid	acid	PROPN
admet-505	438	37	)	)	PUNCT
admet-505	438	38	pka	pka	PROPN
admet-505	438	39	(	(	PUNCT
admet-505	438	40	base	base	NOUN
admet-505	438	41	)	)	PUNCT
admet-505	438	42	t(`c	t(`c	PROPN
admet-505	438	43	)	)	PUNCT
admet-505	439	1	k	k	PROPN
admet-505	439	2	(	(	PUNCT
admet-505	439	3	calc	calc	NOUN
admet-505	439	4	)	)	PUNCT
admet-505	439	5	b	b	PROPN
admet-505	440	1	k	k	PROPN
admet-505	440	2	(	(	PUNCT
admet-505	440	3	obs	obs	PROPN
admet-505	440	4	)	)	PUNCT
admet-505	440	5	c	c	PROPN
admet-505	440	6	±	±	NUM
admet-505	440	7	sd	sd	ADP
admet-505	440	8	n	n	PROPN
admet-505	440	9	d	d	NOUN
admet-505	440	10	log	log	NOUN
admet-505	440	11	kn	kn	PROPN
admet-505	440	12	e	e	PROPN
admet-505	440	13	n	n	PROPN
admet-505	440	14	fbm	fbm	NOUN
admet-505	440	15	nd	nd	PRON
admet-505	440	16	log	log	VERB
admet-505	440	17	poct	poct	PROPN
admet-505	440	18	log	log	NOUN
admet-505	440	19	s0	s0	PROPN
admet-505	440	20	±sd	±sd	PROPN
admet-505	440	21	n	n	CCONJ
admet-505	440	22	σα2	σα2	NOUN
admet-505	440	23	h	h	NOUN
admet-505	440	24	σβ2	σβ2	VERB
admet-505	440	25	h	h	PROPN
admet-505	440	26	π2	π2	PROPN
admet-505	440	27	r2	r2	PROPN
admet-505	440	28	vx	vx	PROPN
admet-505	440	29	comments	comment	NOUN
admet-505	440	30	ref	ref	AUX
admet-505	440	31	glipizide	glipizide	VERB
admet-505	440	32	a	a	DET
admet-505	440	33	5.13	5.13	NUM
admet-505	440	34	25	25	NUM
admet-505	440	35	0.016	0.016	NUM
admet-505	440	36	0.011	0.011	NUM
admet-505	440	37	0.010	0.010	NUM
admet-505	440	38	1	1	NUM
admet-505	440	39	5.8	5.8	NUM
admet-505	440	40	1	1	NUM
admet-505	440	41	0.67	0.67	NUM
admet-505	440	42	0.7	0.7	NUM
admet-505	440	43	2.01	2.01	NUM
admet-505	440	44	-5.53	-5.53	NOUN
admet-505	440	45	0.17	0.17	NUM
admet-505	440	46	6	6	NUM
admet-505	440	47	0.85	0.85	NUM
admet-505	440	48	2.19	2.19	NUM
admet-505	440	49	3.71	3.71	NUM
admet-505	440	50	2.52	2.52	NUM
admet-505	440	51	3.21	3.21	NUM
admet-505	440	52	0.15	0.15	NUM
admet-505	440	53	m	m	NOUN
admet-505	440	54	nacl	nacl	NOUN
admet-505	440	55	[	[	X
admet-505	440	56	39	39	NUM
admet-505	440	57	]	]	PUNCT
admet-505	440	58	hydrocortisone	hydrocortisone	NOUN
admet-505	440	59	n	n	CCONJ
admet-505	440	60	25	25	NUM
admet-505	440	61	0.219	0.219	NUM
admet-505	440	62	0.172	0.172	NUM
admet-505	440	63	0.065	0.065	NUM
admet-505	440	64	7	7	NUM
admet-505	440	65	?	?	SYM
admet-505	440	66	35	35	NUM
admet-505	440	67	11	11	NUM
admet-505	440	68	0.97	0.97	NUM
admet-505	440	69	10.7	10.7	NUM
admet-505	440	70	1.61	1.61	NUM
admet-505	440	71	-3.04	-3.04	NUM
admet-505	440	72	0.07	0.07	NUM
admet-505	440	73	15	15	NUM
admet-505	440	74	0.73	0.73	NUM
admet-505	440	75	1.90	1.90	NUM
admet-505	440	76	2.92	2.92	NUM
admet-505	440	77	2.04	2.04	NUM
admet-505	440	78	2.80	2.80	NUM
admet-505	440	79	[	[	X
admet-505	440	80	40	40	NUM
admet-505	440	81	]	]	PUNCT
admet-505	440	82	ibuprofen	ibuprofen	NOUN
admet-505	440	83	a	a	DET
admet-505	440	84	4.25	4.25	NUM
admet-505	440	85	37	37	NUM
admet-505	440	86	0.100	0.100	NUM
admet-505	440	87	0.294	0.294	NUM
admet-505	440	88	1	1	NUM
admet-505	440	89	68	68	NUM
admet-505	440	90	19	19	NUM
admet-505	440	91	0.96	0.96	NUM
admet-505	440	92	18.2	18.2	NUM
admet-505	440	93	4.13	4.13	NUM
admet-505	440	94	-3.53	-3.53	NOUN
admet-505	440	95	0.20	0.20	NUM
admet-505	440	96	18	18	NUM
admet-505	440	97	0.57	0.57	NUM
admet-505	440	98	0.51	0.51	NUM
admet-505	440	99	1.01	1.01	NUM
admet-505	440	100	0.78	0.78	NUM
admet-505	440	101	1.78	1.78	NUM
admet-505	440	102	0.1	0.1	NUM
admet-505	440	103	m	m	NOUN
admet-505	440	104	hcl	hcl	NOUN
admet-505	440	105	,	,	PUNCT
admet-505	440	106	ph	ph	X
admet-505	440	107	1.2	1.2	NUM
admet-505	440	108	[	[	SYM
admet-505	440	109	41	41	NUM
admet-505	440	110	]	]	PUNCT
admet-505	440	111	ibuprofen	ibuprofen	NOUN
admet-505	440	112	a	a	DET
admet-505	440	113	4.24	4.24	NUM
admet-505	440	114	25	25	NUM
admet-505	440	115	0.086	0.086	NUM
admet-505	440	116	0.248	0.248	NUM
admet-505	440	117	0.004	0.004	NUM
admet-505	440	118	9	9	NUM
admet-505	440	119	61	61	NUM
admet-505	440	120	16	16	NUM
admet-505	440	121	0.96	0.96	NUM
admet-505	440	122	15.4	15.4	NUM
admet-505	440	123	4.13	4.13	NUM
admet-505	440	124	-3.70	-3.70	NUM
admet-505	440	125	0.20	0.20	NUM
admet-505	440	126	18	18	NUM
admet-505	440	127	0.57	0.57	NUM
admet-505	440	128	0.51	0.51	NUM
admet-505	440	129	1.01	1.01	NUM
admet-505	440	130	0.78	0.78	NUM
admet-505	440	131	1.78	1.78	NUM
admet-505	440	132	[	[	X
admet-505	440	133	42	42	NUM
admet-505	440	134	]	]	PUNCT
admet-505	440	135	ibuprofen	ibuprofen	NOUN
admet-505	440	136	a	a	DET
admet-505	440	137	4.24	4.24	NUM
admet-505	440	138	27	27	NUM
admet-505	440	139	0.086	0.086	NUM
admet-505	440	140	0.362	0.362	NUM
admet-505	440	141	0.017	0.017	NUM
admet-505	440	142	5	5	NUM
admet-505	440	143	87	87	NUM
admet-505	440	144	23	23	NUM
admet-505	440	145	0.98	0.98	NUM
admet-505	440	146	22.4	22.4	NUM
admet-505	440	147	4.13	4.13	NUM
admet-505	440	148	-3.70	-3.70	NUM
admet-505	440	149	0.20	0.20	NUM
admet-505	440	150	18	18	NUM
admet-505	440	151	0.57	0.57	NUM
admet-505	440	152	0.51	0.51	NUM
admet-505	440	153	1.01	1.01	NUM
admet-505	440	154	0.78	0.78	NUM
admet-505	440	155	1.78	1.78	NUM
admet-505	440	156	[	[	X
admet-505	440	157	43	43	NUM
admet-505	440	158	]	]	X
admet-505	440	159	ibuprofen	ibuprofen	NOUN
admet-505	440	160	a	a	DET
admet-505	440	161	4.24	4.24	NUM
admet-505	440	162	27	27	NUM
admet-505	440	163	0.086	0.086	NUM
admet-505	440	164	0.255	0.255	NUM
admet-505	440	165	0.013	0.013	NUM
admet-505	440	166	6	6	NUM
admet-505	440	167	61	61	NUM
admet-505	440	168	16	16	NUM
admet-505	440	169	0.99	0.99	NUM
admet-505	440	170	15.8	15.8	NUM
admet-505	440	171	4.13	4.13	NUM
admet-505	440	172	-3.70	-3.70	NUM
admet-505	440	173	0.20	0.20	NUM
admet-505	440	174	18	18	NUM
admet-505	440	175	0.57	0.57	NUM
admet-505	440	176	0.51	0.51	NUM
admet-505	440	177	1.01	1.01	NUM
admet-505	440	178	0.78	0.78	NUM
admet-505	440	179	1.78	1.78	NUM
admet-505	440	180	[	[	X
admet-505	440	181	44	44	NUM
admet-505	440	182	]	]	PUNCT
admet-505	440	183	ibuprofen	ibuprofen	NOUN
admet-505	440	184	a	a	DET
admet-505	440	185	4.25	4.25	NUM
admet-505	440	186	37	37	NUM
admet-505	440	187	0.100	0.100	NUM
admet-505	440	188	0.409	0.409	NUM
admet-505	440	189	0.016	0.016	NUM
admet-505	440	190	6	6	NUM
admet-505	440	191	93	93	NUM
admet-505	440	192	26	26	NUM
admet-505	440	193	0.98	0.98	NUM
admet-505	440	194	25.4	25.4	NUM
admet-505	440	195	4.13	4.13	NUM
admet-505	440	196	-3.53	-3.53	NOUN
admet-505	440	197	0.20	0.20	NUM
admet-505	440	198	18	18	NUM
admet-505	440	199	0.57	0.57	NUM
admet-505	440	200	0.51	0.51	NUM
admet-505	440	201	1.01	1.01	NUM
admet-505	440	202	0.78	0.78	NUM
admet-505	440	203	1.78	1.78	NUM
admet-505	440	204	[	[	X
admet-505	440	205	44	44	NUM
admet-505	440	206	]	]	PUNCT
admet-505	440	207	indomethacin	indomethacin	VERB
admet-505	440	208	a	a	DET
admet-505	440	209	4.13	4.13	NUM
admet-505	440	210	37	37	NUM
admet-505	440	211	0.021	0.021	NUM
admet-505	440	212	0.024	0.024	NUM
admet-505	440	213	0.000	0.000	NUM
admet-505	440	214	6	6	NUM
admet-505	440	215	11	11	NUM
admet-505	440	216	2	2	NUM
admet-505	440	217	0.73	0.73	NUM
admet-505	440	218	1.5	1.5	NUM
admet-505	440	219	3.51	3.51	NUM
admet-505	440	220	-5.23	-5.23	NUM
admet-505	440	221	0.22	0.22	NUM
admet-505	440	222	20	20	NUM
admet-505	440	223	0.57	0.57	NUM
admet-505	440	224	1.24	1.24	NUM
admet-505	440	225	2.49	2.49	NUM
admet-505	440	226	2.44	2.44	NUM
admet-505	440	227	2.53	2.53	NUM
admet-505	440	228	[	[	X
admet-505	440	229	45	45	NUM
admet-505	440	230	]	]	PUNCT
admet-505	440	231	ketoprofen	ketoprofen	VERB
admet-505	440	232	a	a	DET
admet-505	440	233	4.00	4.00	NUM
admet-505	440	234	37	37	NUM
admet-505	440	235	0.132	0.132	NUM
admet-505	440	236	0.840	0.840	NUM
admet-505	440	237	0.097	0.097	NUM
admet-505	440	238	3	3	NUM
admet-505	440	239	173	173	NUM
admet-505	440	240	53	53	NUM
admet-505	440	241	0.98	0.98	NUM
admet-505	440	242	52.1	52.1	NUM
admet-505	440	243	3.16	3.16	NUM
admet-505	440	244	-3.23	-3.23	NUM
admet-505	440	245	0.25	0.25	NUM
admet-505	440	246	19	19	NUM
admet-505	440	247	0.57	0.57	NUM
admet-505	440	248	0.87	0.87	NUM
admet-505	440	249	1.97	1.97	NUM
admet-505	440	250	1.56	1.56	NUM
admet-505	440	251	1.98	1.98	NUM
admet-505	440	252	ph	ph	NOUN
admet-505	440	253	4.0	4.0	NUM
admet-505	440	254	[	[	SYM
admet-505	440	255	46	46	NUM
admet-505	440	256	]	]	PUNCT
admet-505	440	257	ketoprofen	ketoprofen	VERB
admet-505	440	258	a	a	DET
admet-505	440	259	4.00	4.00	NUM
admet-505	440	260	37	37	NUM
admet-505	440	261	0.132	0.132	NUM
admet-505	440	262	0.946	0.946	NUM
admet-505	440	263	0.093	0.093	NUM
admet-505	440	264	3	3	NUM
admet-505	440	265	193	193	NUM
admet-505	440	266	59	59	NUM
admet-505	440	267	0.99	0.99	NUM
admet-505	440	268	58.7	58.7	NUM
admet-505	440	269	3.16	3.16	NUM
admet-505	440	270	-3.23	-3.23	NUM
admet-505	440	271	0.25	0.25	NUM
admet-505	440	272	19	19	NUM
admet-505	440	273	0.57	0.57	NUM
admet-505	440	274	0.87	0.87	NUM
admet-505	440	275	1.97	1.97	NUM
admet-505	440	276	1.56	1.56	NUM
admet-505	440	277	1.98	1.98	NUM
admet-505	440	278	ph	ph	NOUN
admet-505	440	279	4.6	4.6	NUM
admet-505	440	280	[	[	SYM
admet-505	440	281	46	46	NUM
admet-505	440	282	]	]	PUNCT
admet-505	440	283	ketoprofen	ketoprofen	VERB
admet-505	440	284	a	a	DET
admet-505	440	285	4.00	4.00	NUM
admet-505	440	286	37	37	NUM
admet-505	440	287	0.132	0.132	NUM
admet-505	440	288	1.052	1.052	NUM
admet-505	440	289	0.117	0.117	NUM
admet-505	440	290	3	3	NUM
admet-505	440	291	215	215	NUM
admet-505	440	292	66	66	NUM
admet-505	440	293	0.99	0.99	NUM
admet-505	440	294	65.2	65.2	NUM
admet-505	440	295	3.16	3.16	NUM
admet-505	440	296	-3.23	-3.23	NUM
admet-505	440	297	0.25	0.25	NUM
admet-505	440	298	19	19	NUM
admet-505	440	299	0.57	0.57	NUM
admet-505	440	300	0.87	0.87	NUM
admet-505	440	301	1.97	1.97	NUM
admet-505	440	302	1.56	1.56	NUM
admet-505	440	303	1.98	1.98	NUM
admet-505	440	304	ph	ph	NOUN
admet-505	440	305	6.0	6.0	NUM
admet-505	440	306	[	[	NOUN
admet-505	440	307	46	46	NUM
admet-505	440	308	]	]	PUNCT
admet-505	440	309	ketoprofen	ketoprofen	VERB
admet-505	440	310	a	a	DET
admet-505	440	311	4.00	4.00	NUM
admet-505	440	312	37	37	NUM
admet-505	440	313	0.132	0.132	NUM
admet-505	440	314	1.091	1.091	NUM
admet-505	440	315	0.045	0.045	NUM
admet-505	440	316	3	3	NUM
admet-505	440	317	222	222	NUM
admet-505	440	318	68	68	NUM
admet-505	440	319	0.99	0.99	NUM
admet-505	440	320	67.6	67.6	NUM
admet-505	440	321	3.16	3.16	NUM
admet-505	440	322	-3.23	-3.23	NUM
admet-505	440	323	0.25	0.25	NUM
admet-505	440	324	19	19	NUM
admet-505	440	325	0.57	0.57	NUM
admet-505	440	326	0.87	0.87	NUM
admet-505	440	327	1.97	1.97	NUM
admet-505	440	328	1.56	1.56	NUM
admet-505	440	329	1.98	1.98	NUM
admet-505	440	330	ph	ph	NOUN
admet-505	440	331	6.8	6.8	NUM
admet-505	440	332	[	[	X
admet-505	440	333	46	46	NUM
admet-505	440	334	]	]	X
admet-505	440	335	loratadine	loratadine	PROPN
admet-505	440	336	b	b	PROPN
admet-505	440	337	5.25	5.25	NUM
admet-505	440	338	25	25	NUM
admet-505	440	339	0.027	0.027	NUM
admet-505	440	340	0.119	0.119	NUM
admet-505	440	341	1	1	NUM
admet-505	440	342	42	42	NUM
admet-505	440	343	8	8	NUM
admet-505	440	344	0.92	0.92	NUM
admet-505	440	345	7.4	7.4	NUM
admet-505	440	346	5.20	5.20	NUM
admet-505	440	347	-5.17	-5.17	NUM
admet-505	440	348	0.30	0.30	NUM
admet-505	440	349	3	3	NUM
admet-505	440	350	0.00	0.00	NUM
admet-505	440	351	1.14	1.14	NUM
admet-505	440	352	2.09	2.09	NUM
admet-505	440	353	2.19	2.19	NUM
admet-505	440	354	2.87	2.87	NUM
admet-505	440	355	[	[	X
admet-505	440	356	47	47	NUM
admet-505	440	357	]	]	PUNCT
admet-505	440	358	mefenamic	mefenamic	NOUN
admet-505	440	359	acid	acid	NOUN
admet-505	440	360	a	a	DET
admet-505	440	361	4.19	4.19	NUM
admet-505	440	362	37	37	NUM
admet-505	440	363	0.0089	0.0089	NUM
admet-505	440	364	0.0036	0.0036	NUM
admet-505	440	365	0.0002	0.0002	NUM
admet-505	440	366	8	8	NUM
admet-505	440	367	5.6	5.6	NUM
admet-505	440	368	1	1	NUM
admet-505	440	369	0.22	0.22	NUM
admet-505	440	370	0.2	0.2	NUM
admet-505	440	371	5.12	5.12	NUM
admet-505	440	372	-6.19	-6.19	NUM
admet-505	440	373	0.38	0.38	NUM
admet-505	440	374	8	8	NUM
admet-505	440	375	0.65	0.65	NUM
admet-505	440	376	0.70	0.70	NUM
admet-505	440	377	1.47	1.47	NUM
admet-505	440	378	1.65	1.65	NUM
admet-505	440	379	1.92	1.92	NUM
admet-505	440	380	50	50	NUM
admet-505	440	381	mm	mm	NOUN
admet-505	440	382	po4	po4	PROPN
admet-505	441	1	[	[	X
admet-505	441	2	41	41	NUM
admet-505	441	3	]	]	X
admet-505	441	4	mefenamic	mefenamic	NOUN
admet-505	441	5	acid	acid	NOUN
admet-505	441	6	a	a	DET
admet-505	441	7	4.19	4.19	NUM
admet-505	441	8	37	37	NUM
admet-505	441	9	0.0089	0.0089	NUM
admet-505	441	10	0.0044	0.0044	NUM
admet-505	441	11	0.0001	0.0001	NUM
admet-505	441	12	6	6	NUM
admet-505	441	13	5.8	5.8	NUM
admet-505	441	14	1	1	NUM
admet-505	441	15	0.27	0.27	NUM
admet-505	441	16	0.3	0.3	NUM
admet-505	441	17	5.12	5.12	NUM
admet-505	441	18	-6.19	-6.19	NUM
admet-505	441	19	0.38	0.38	NUM
admet-505	441	20	8	8	NUM
admet-505	441	21	0.65	0.65	NUM
admet-505	441	22	0.70	0.70	NUM
admet-505	441	23	1.47	1.47	NUM
admet-505	441	24	1.65	1.65	NUM
admet-505	441	25	1.92	1.92	NUM
admet-505	441	26	50	50	NUM
admet-505	441	27	mm	mm	NOUN
admet-505	441	28	po4	po4	PROPN
admet-505	441	29	+	+	CCONJ
admet-505	441	30	100	100	NUM
admet-505	441	31	mm	mm	NOUN
admet-505	441	32	nacl	nacl	NOUN
admet-505	442	1	[	[	X
admet-505	442	2	41	41	NUM
admet-505	442	3	]	]	X
admet-505	442	4	mefenamic	mefenamic	NOUN
admet-505	442	5	acid	acid	NOUN
admet-505	442	6	a	a	DET
admet-505	442	7	4.19	4.19	NUM
admet-505	442	8	37	37	NUM
admet-505	442	9	0.0089	0.0089	NUM
admet-505	442	10	0.0036	0.0036	NUM
admet-505	442	11	0.0003	0.0003	NUM
admet-505	442	12	6	6	NUM
admet-505	442	13	5.6	5.6	NUM
admet-505	442	14	1	1	NUM
admet-505	442	15	0.22	0.22	NUM
admet-505	442	16	0.2	0.2	NUM
admet-505	442	17	5.12	5.12	NUM
admet-505	442	18	-6.19	-6.19	NUM
admet-505	442	19	0.38	0.38	NUM
admet-505	442	20	8	8	NUM
admet-505	442	21	0.65	0.65	NUM
admet-505	442	22	0.70	0.70	NUM
admet-505	442	23	1.47	1.47	NUM
admet-505	442	24	1.65	1.65	NUM
admet-505	442	25	1.92	1.92	NUM
admet-505	442	26	50	50	NUM
admet-505	442	27	mm	mm	NOUN
admet-505	442	28	po4	po4	PROPN
admet-505	442	29	+	+	CCONJ
admet-505	442	30	50	50	NUM
admet-505	442	31	mm	mm	NOUN
admet-505	442	32	nacl	nacl	NOUN
admet-505	443	1	[	[	X
admet-505	443	2	41	41	NUM
admet-505	443	3	]	]	PUNCT
admet-505	443	4	nimesulide	nimesulide	ADP
admet-505	443	5	a	a	DET
admet-505	443	6	6.31	6.31	NUM
admet-505	443	7	37	37	NUM
admet-505	443	8	0.046	0.046	NUM
admet-505	443	9	0.017	0.017	NUM
admet-505	443	10	1	1	NUM
admet-505	443	11	8.8	8.8	NUM
admet-505	443	12	2	2	NUM
admet-505	443	13	0.52	0.52	NUM
admet-505	443	14	1.0	1.0	NUM
admet-505	443	15	2.39	2.39	NUM
admet-505	443	16	-4.38	-4.38	NUM
admet-505	443	17	0.24	0.24	NUM
admet-505	443	18	4	4	NUM
admet-505	443	19	0.43	0.43	NUM
admet-505	443	20	1.10	1.10	NUM
admet-505	443	21	2.68	2.68	NUM
admet-505	443	22	2.03	2.03	NUM
admet-505	443	23	1.99	1.99	NUM
admet-505	443	24	50	50	NUM
admet-505	443	25	mm	mm	PROPN
admet-505	443	26	po4	po4	PROPN
admet-505	443	27	,	,	PUNCT
admet-505	443	28	ph	ph	X
admet-505	443	29	6.8	6.8	NUM
admet-505	443	30	[	[	X
admet-505	443	31	41	41	NUM
admet-505	443	32	]	]	PUNCT
admet-505	443	33	nsc-639829	nsc-639829	NOUN
admet-505	444	1	b	b	PROPN
admet-505	444	2	3.76	3.76	NUM
admet-505	444	3	25	25	NUM
admet-505	444	4	0.002	0.002	NUM
admet-505	444	5	0.058	0.058	NUM
admet-505	444	6	0.005	0.005	NUM
admet-505	444	7	8	8	NUM
admet-505	444	8	30	30	NUM
admet-505	444	9	4	4	NUM
admet-505	444	10	0.90	0.90	NUM
admet-505	444	11	3.6	3.6	NUM
admet-505	444	12	6.21	6.21	NUM
admet-505	444	13	-7.24	-7.24	NUM
admet-505	444	14	0.06	0.06	NUM
admet-505	444	15	1	1	NUM
admet-505	444	16	0.60	0.60	NUM
admet-505	444	17	2.03	2.03	NUM
admet-505	444	18	3.25	3.25	NUM
admet-505	444	19	3.00	3.00	NUM
admet-505	444	20	3.12	3.12	NUM
admet-505	444	21	[	[	X
admet-505	444	22	48	48	NUM
admet-505	444	23	]	]	PUNCT
admet-505	444	24	oxazepam	oxazepam	PROPN
admet-505	444	25	b	b	PROPN
admet-505	444	26	1.90	1.90	NUM
admet-505	444	27	24	24	NUM
admet-505	444	28	0.111	0.111	NUM
admet-505	444	29	0.167	0.167	NUM
admet-505	444	30	0.003	0.003	NUM
admet-505	444	31	3	3	NUM
admet-505	444	32	46	46	NUM
admet-505	444	33	11	11	NUM
admet-505	444	34	0.94	0.94	NUM
admet-505	444	35	10.3	10.3	NUM
admet-505	444	36	2.24	2.24	NUM
admet-505	444	37	-4.03	-4.03	NUM
admet-505	444	38	0.17	0.17	NUM
admet-505	444	39	5	5	NUM
admet-505	444	40	0.64	0.64	NUM
admet-505	444	41	1.29	1.29	NUM
admet-505	444	42	1.75	1.75	NUM
admet-505	444	43	2.23	2.23	NUM
admet-505	444	44	1.99	1.99	NUM
admet-505	444	45	[	[	X
admet-505	444	46	36	36	NUM
admet-505	444	47	]	]	PUNCT
admet-505	444	48	paraben	paraben	NOUN
admet-505	444	49	,	,	PUNCT
admet-505	444	50	eta	eta	PROPN
admet-505	444	51	8.35	8.35	NUM
admet-505	444	52	24	24	NUM
admet-505	444	53	0.313	0.313	NUM
admet-505	444	54	0.478	0.478	NUM
admet-505	444	55	0.017	0.017	NUM
admet-505	444	56	3	3	NUM
admet-505	444	57	70	70	NUM
admet-505	444	58	30	30	NUM
admet-505	444	59	0.99	0.99	NUM
admet-505	444	60	29.7	29.7	NUM
admet-505	444	61	2.47	2.47	NUM
admet-505	444	62	-2.28	-2.28	NOUN
admet-505	444	63	0.07	0.07	NUM
admet-505	444	64	6	6	NUM
admet-505	444	65	0.66	0.66	NUM
admet-505	444	66	0.72	0.72	NUM
admet-505	444	67	1.25	1.25	NUM
admet-505	444	68	0.87	0.87	NUM
admet-505	444	69	1.27	1.27	NUM
admet-505	444	70	[	[	X
admet-505	444	71	36	36	NUM
admet-505	444	72	]	]	PUNCT
admet-505	444	73	paraben	paraben	NOUN
admet-505	444	74	,	,	PUNCT
admet-505	444	75	mea	mea	NOUN
admet-505	444	76	8.35	8.35	NUM
admet-505	444	77	24	24	NUM
admet-505	444	78	0.476	0.476	NUM
admet-505	444	79	0.561	0.561	NUM
admet-505	444	80	0.037	0.037	NUM
admet-505	444	81	3	3	NUM
admet-505	444	82	66	66	NUM
admet-505	444	83	35	35	NUM
admet-505	444	84	0.99	0.99	NUM
admet-505	444	85	34.8	34.8	NUM
admet-505	444	86	1.96	1.96	NUM
admet-505	444	87	-1.82	-1.82	NUM
admet-505	444	88	0.11	0.11	NUM
admet-505	444	89	8	8	NUM
admet-505	444	90	0.66	0.66	NUM
admet-505	444	91	0.72	0.72	NUM
admet-505	444	92	1.24	1.24	NUM
admet-505	444	93	0.87	0.87	NUM
admet-505	444	94	1.13	1.13	NUM
admet-505	444	95	[	[	X
admet-505	444	96	36	36	NUM
admet-505	444	97	]	]	PUNCT
admet-505	444	98	paraben	paraben	NOUN
admet-505	444	99	,	,	PUNCT
admet-505	444	100	mea	mea	NOUN
admet-505	444	101	8.35	8.35	NUM
admet-505	444	102	24	24	NUM
admet-505	444	103	0.476	0.476	NUM
admet-505	444	104	0.340	0.340	NUM
admet-505	444	105	0.010	0.010	NUM
admet-505	444	106	3	3	NUM
admet-505	444	107	41	41	NUM
admet-505	444	108	22	22	NUM
admet-505	444	109	0.96	0.96	NUM
admet-505	444	110	21.1	21.1	NUM
admet-505	444	111	1.96	1.96	NUM
admet-505	444	112	-1.82	-1.82	NUM
admet-505	444	113	0.11	0.11	NUM
admet-505	444	114	8	8	NUM
admet-505	444	115	0.66	0.66	NUM
admet-505	444	116	0.72	0.72	NUM
admet-505	444	117	1.24	1.24	NUM
admet-505	444	118	0.87	0.87	NUM
admet-505	444	119	1.13	1.13	NUM
admet-505	444	120	0.15	0.15	NUM
admet-505	444	121	m	m	NOUN
admet-505	444	122	nacl	nacl	NOUN
admet-505	444	123	[	[	X
admet-505	444	124	36	36	NUM
admet-505	444	125	]	]	PUNCT
admet-505	444	126	paraben	paraben	NOUN
admet-505	444	127	,	,	PUNCT
admet-505	444	128	n	n	CCONJ
admet-505	444	129	-	-	PUNCT
admet-505	444	130	bua	bua	PROPN
admet-505	444	131	8.47	8.47	NUM
admet-505	444	132	24	24	NUM
admet-505	444	133	0.177	0.177	NUM
admet-505	444	134	0.641	0.641	NUM
admet-505	444	135	0.001	0.001	NUM
admet-505	444	136	3	3	NUM
admet-505	444	137	118	118	NUM
admet-505	444	138	40	40	NUM
admet-505	444	139	0.99	0.99	NUM
admet-505	444	140	39.7	39.7	NUM
admet-505	444	141	3.57	3.57	NUM
admet-505	444	142	-2.91	-2.91	NUM
admet-505	444	143	0.15	0.15	NUM
admet-505	444	144	13	13	NUM
admet-505	444	145	0.66	0.66	NUM
admet-505	444	146	0.73	0.73	NUM
admet-505	444	147	1.26	1.26	NUM
admet-505	444	148	0.87	0.87	NUM
admet-505	444	149	1.55	1.55	NUM
admet-505	444	150	[	[	X
admet-505	444	151	36	36	NUM
admet-505	444	152	]	]	X
admet-505	444	153	pg-300995	pg-300995	PROPN
admet-505	444	154	b	b	PROPN
admet-505	444	155	3.58	3.58	NUM
admet-505	444	156	25	25	NUM
admet-505	444	157	0.192	0.192	NUM
admet-505	444	158	0.085	0.085	NUM
admet-505	444	159	0.006	0.006	NUM
admet-505	444	160	5	5	NUM
admet-505	444	161	22	22	NUM
admet-505	444	162	6	6	NUM
admet-505	444	163	0.88	0.88	NUM
admet-505	444	164	5.3	5.3	NUM
admet-505	444	165	2.60	2.60	NUM
admet-505	444	166	-3.59	-3.59	NUM
admet-505	444	167	0.03	0.03	NUM
admet-505	444	168	1	1	NUM
admet-505	444	169	0.35	0.35	NUM
admet-505	444	170	0.74	0.74	NUM
admet-505	444	171	1.78	1.78	NUM
admet-505	444	172	2.12	2.12	NUM
admet-505	444	173	1.40	1.40	NUM
admet-505	444	174	ph	ph	NOUN
admet-505	444	175	1.0	1.0	NUM
admet-505	444	176	[	[	SYM
admet-505	444	177	49	49	NUM
admet-505	444	178	]	]	PUNCT
admet-505	444	179	alex	alex	PROPN
admet-505	444	180	avdeef	avdeef	PROPN
admet-505	444	181	admet	admet	PROPN
admet-505	444	182	&	&	CCONJ
admet-505	444	183	dmpk	dmpk	PROPN
admet-505	444	184	6(2	6(2	NUM
admet-505	444	185	)	)	PUNCT
admet-505	444	186	(	(	PUNCT
admet-505	444	187	2018	2018	NUM
admet-505	444	188	)	)	PUNCT
admet-505	445	1	105	105	NUM
admet-505	445	2	-	-	SYM
admet-505	445	3	139	139	NUM
admet-505	445	4	116	116	NUM
admet-505	445	5	table	table	NOUN
admet-505	445	6	1	1	NUM
admet-505	445	7	.	.	NUM
admet-505	445	8	continued	continue	VERB
admet-505	445	9	…	…	PUNCT
admet-505	445	10	compound	compound	NOUN
admet-505	445	11	type	type	NOUN
admet-505	445	12	pka	pka	PROPN
admet-505	445	13	(	(	PUNCT
admet-505	445	14	acid	acid	PROPN
admet-505	445	15	)	)	PUNCT
admet-505	445	16	pka	pka	PROPN
admet-505	445	17	(	(	PUNCT
admet-505	445	18	base	base	NOUN
admet-505	445	19	)	)	PUNCT
admet-505	445	20	t(`c	t(`c	PROPN
admet-505	445	21	)	)	PUNCT
admet-505	446	1	k	k	PROPN
admet-505	446	2	(	(	PUNCT
admet-505	446	3	calc	calc	NOUN
admet-505	446	4	)	)	PUNCT
admet-505	446	5	b	b	PROPN
admet-505	447	1	k	k	PROPN
admet-505	447	2	(	(	PUNCT
admet-505	447	3	obs	obs	PROPN
admet-505	447	4	)	)	PUNCT
admet-505	447	5	c	c	PROPN
admet-505	447	6	±	±	NUM
admet-505	447	7	sd	sd	ADP
admet-505	447	8	n	n	PROPN
admet-505	447	9	d	d	NOUN
admet-505	447	10	log	log	NOUN
admet-505	447	11	kn	kn	PROPN
admet-505	447	12	e	e	PROPN
admet-505	447	13	n	n	PROPN
admet-505	447	14	fbm	fbm	NOUN
admet-505	447	15	nd	nd	PRON
admet-505	447	16	log	log	VERB
admet-505	447	17	poct	poct	PROPN
admet-505	447	18	log	log	NOUN
admet-505	447	19	s0	s0	PROPN
admet-505	447	20	±sd	±sd	PROPN
admet-505	447	21	n	n	CCONJ
admet-505	447	22	σα2	σα2	NOUN
admet-505	447	23	h	h	NOUN
admet-505	447	24	σβ2	σβ2	VERB
admet-505	447	25	h	h	PROPN
admet-505	447	26	π2	π2	PROPN
admet-505	447	27	r2	r2	PROPN
admet-505	447	28	vx	vx	PROPN
admet-505	447	29	comments	comment	NOUN
admet-505	447	30	ref	ref	VERB
admet-505	447	31	pg-300995	pg-300995	PROPN
admet-505	447	32	b	b	PROPN
admet-505	447	33	3.58	3.58	NUM
admet-505	447	34	25	25	NUM
admet-505	447	35	0.192	0.192	NUM
admet-505	447	36	0.082	0.082	NUM
admet-505	447	37	0.003	0.003	NUM
admet-505	447	38	9	9	NUM
admet-505	447	39	7	7	NUM
admet-505	447	40	6	6	NUM
admet-505	447	41	0.00	0.00	NUM
admet-505	447	42	5.1	5.1	NUM
admet-505	447	43	2.60	2.60	NUM
admet-505	447	44	-3.59	-3.59	NUM
admet-505	447	45	0.03	0.03	NUM
admet-505	447	46	1	1	NUM
admet-505	447	47	0.35	0.35	NUM
admet-505	447	48	0.74	0.74	NUM
admet-505	447	49	1.78	1.78	NUM
admet-505	447	50	2.12	2.12	NUM
admet-505	447	51	1.40	1.40	NUM
admet-505	447	52	ph	ph	NOUN
admet-505	447	53	2.0	2.0	NUM
admet-505	447	54	[	[	SYM
admet-505	447	55	49	49	NUM
admet-505	447	56	]	]	X
admet-505	447	57	pg-300995	pg-300995	PROPN
admet-505	447	58	b	b	PROPN
admet-505	447	59	3.58	3.58	NUM
admet-505	447	60	25	25	NUM
admet-505	447	61	0.192	0.192	NUM
admet-505	447	62	0.081	0.081	NUM
admet-505	447	63	0.004	0.004	NUM
admet-505	447	64	5	5	NUM
admet-505	447	65	19	19	NUM
admet-505	447	66	6	6	NUM
admet-505	447	67	0.00	0.00	NUM
admet-505	447	68	5.0	5.0	NUM
admet-505	447	69	2.60	2.60	NUM
admet-505	447	70	-3.59	-3.59	NUM
admet-505	447	71	0.03	0.03	NUM
admet-505	447	72	1	1	NUM
admet-505	447	73	0.35	0.35	NUM
admet-505	447	74	0.74	0.74	NUM
admet-505	447	75	1.78	1.78	NUM
admet-505	447	76	2.12	2.12	NUM
admet-505	447	77	1.40	1.40	NUM
admet-505	447	78	ph	ph	NOUN
admet-505	447	79	3.0	3.0	NUM
admet-505	447	80	[	[	X
admet-505	447	81	49	49	NUM
admet-505	447	82	]	]	X
admet-505	447	83	pg-300995	pg-300995	PROPN
admet-505	447	84	b	b	PROPN
admet-505	447	85	3.58	3.58	NUM
admet-505	447	86	25	25	NUM
admet-505	447	87	0.192	0.192	NUM
admet-505	447	88	0.022	0.022	NUM
admet-505	447	89	0.001	0.001	NUM
admet-505	447	90	5	5	NUM
admet-505	447	91	7.5	7.5	NUM
admet-505	447	92	2	2	NUM
admet-505	447	93	0.68	0.68	NUM
admet-505	447	94	1.4	1.4	NUM
admet-505	447	95	2.60	2.60	NUM
admet-505	447	96	-3.59	-3.59	NUM
admet-505	447	97	0.03	0.03	NUM
admet-505	447	98	1	1	NUM
admet-505	447	99	0.35	0.35	NUM
admet-505	447	100	0.74	0.74	NUM
admet-505	447	101	1.78	1.78	NUM
admet-505	447	102	2.12	2.12	NUM
admet-505	447	103	1.40	1.40	NUM
admet-505	447	104	ph	ph	NOUN
admet-505	447	105	7.0	7.0	NUM
admet-505	447	106	[	[	X
admet-505	447	107	49	49	NUM
admet-505	447	108	]	]	PUNCT
admet-505	447	109	phenytoin	phenytoin	VERB
admet-505	447	110	a	a	DET
admet-505	447	111	8.28	8.28	NUM
admet-505	447	112	25	25	NUM
admet-505	447	113	0.063	0.063	NUM
admet-505	447	114	0.023	0.023	NUM
admet-505	447	115	0.0002	0.0002	NUM
admet-505	447	116	4	4	NUM
admet-505	447	117	8.5	8.5	NUM
admet-505	447	118	2	2	NUM
admet-505	447	119	0.73	0.73	NUM
admet-505	447	120	1.5	1.5	NUM
admet-505	447	121	2.24	2.24	NUM
admet-505	447	122	-4.05	-4.05	NOUN
admet-505	447	123	0.11	0.11	NUM
admet-505	447	124	21	21	NUM
admet-505	447	125	0.44	0.44	NUM
admet-505	447	126	1.14	1.14	NUM
admet-505	447	127	2.04	2.04	NUM
admet-505	447	128	1.94	1.94	NUM
admet-505	447	129	1.87	1.87	NUM
admet-505	448	1	[	[	X
admet-505	448	2	50	50	NUM
admet-505	448	3	]	]	PUNCT
admet-505	448	4	pioglitazone	pioglitazone	NOUN
admet-505	448	5	ab	ab	NOUN
admet-505	448	6	5.63	5.63	NUM
admet-505	448	7	6.63	6.63	NUM
admet-505	448	8	25	25	NUM
admet-505	448	9	0.028	0.028	NUM
admet-505	448	10	0.023	0.023	NUM
admet-505	448	11	0.023	0.023	NUM
admet-505	448	12	1	1	NUM
admet-505	448	13	13	13	NUM
admet-505	448	14	2	2	NUM
admet-505	448	15	0.72	0.72	NUM
admet-505	448	16	1.4	1.4	NUM
admet-505	448	17	2.94	2.94	NUM
admet-505	448	18	-6.32	-6.32	PUNCT
admet-505	448	19	0.23	0.23	NUM
admet-505	448	20	2	2	NUM
admet-505	448	21	0.34	0.34	NUM
admet-505	448	22	1.64	1.64	NUM
admet-505	448	23	2.37	2.37	NUM
admet-505	448	24	2.33	2.33	NUM
admet-505	448	25	2.66	2.66	NUM
admet-505	448	26	[	[	X
admet-505	448	27	39	39	NUM
admet-505	448	28	]	]	PUNCT
admet-505	448	29	pioglitazone	pioglitazone	NOUN
admet-505	448	30	ab	ab	NOUN
admet-505	448	31	5.63	5.63	NUM
admet-505	448	32	6.63	6.63	NUM
admet-505	448	33	25	25	NUM
admet-505	448	34	0.028	0.028	NUM
admet-505	448	35	0.026	0.026	NUM
admet-505	448	36	0.025	0.025	NUM
admet-505	448	37	1	1	NUM
admet-505	448	38	13	13	NUM
admet-505	448	39	2	2	NUM
admet-505	448	40	0.80	0.80	NUM
admet-505	448	41	1.6	1.6	NUM
admet-505	448	42	2.94	2.94	NUM
admet-505	448	43	-6.32	-6.32	PUNCT
admet-505	448	44	0.23	0.23	NUM
admet-505	448	45	2	2	NUM
admet-505	448	46	0.34	0.34	NUM
admet-505	448	47	1.64	1.64	NUM
admet-505	448	48	2.37	2.37	NUM
admet-505	448	49	2.33	2.33	NUM
admet-505	448	50	2.66	2.66	NUM
admet-505	448	51	0.15	0.15	NUM
admet-505	448	52	m	m	NOUN
admet-505	448	53	nacl	nacl	NOUN
admet-505	448	54	[	[	X
admet-505	448	55	39	39	NUM
admet-505	448	56	]	]	PUNCT
admet-505	448	57	piroxicam	piroxicam	NOUN
admet-505	448	58	ab	ab	PROPN
admet-505	448	59	1.76	1.76	NUM
admet-505	448	60	4.96	4.96	NUM
admet-505	448	61	37	37	NUM
admet-505	448	62	0.023	0.023	NUM
admet-505	448	63	0.019	0.019	NUM
admet-505	448	64	0.001	0.001	NUM
admet-505	448	65	3	3	NUM
admet-505	448	66	8.8	8.8	NUM
admet-505	448	67	2	2	NUM
admet-505	448	68	0.58	0.58	NUM
admet-505	448	69	1.2	1.2	NUM
admet-505	448	70	1.98	1.98	NUM
admet-505	448	71	-4.33	-4.33	NUM
admet-505	448	72	0.33	0.33	NUM
admet-505	448	73	18	18	NUM
admet-505	448	74	0.72	0.72	NUM
admet-505	448	75	2.12	2.12	NUM
admet-505	448	76	3.12	3.12	NUM
admet-505	448	77	2.56	2.56	NUM
admet-505	448	78	2.16	2.16	NUM
admet-505	448	79	ph	ph	NOUN
admet-505	448	80	4.0	4.0	NUM
admet-505	448	81	[	[	SYM
admet-505	448	82	51	51	NUM
admet-505	448	83	]	]	X
admet-505	448	84	piroxicam	piroxicam	NOUN
admet-505	448	85	ab	ab	PROPN
admet-505	448	86	1.76	1.76	NUM
admet-505	448	87	4.96	4.96	NUM
admet-505	448	88	37	37	NUM
admet-505	448	89	0.023	0.023	NUM
admet-505	448	90	0.020	0.020	NUM
admet-505	448	91	0.002	0.002	NUM
admet-505	448	92	3	3	NUM
admet-505	448	93	8.8	8.8	NUM
admet-505	448	94	2	2	NUM
admet-505	448	95	0.60	0.60	NUM
admet-505	448	96	1.2	1.2	NUM
admet-505	448	97	1.98	1.98	NUM
admet-505	448	98	-4.33	-4.33	NUM
admet-505	448	99	0.33	0.33	NUM
admet-505	448	100	18	18	NUM
admet-505	448	101	0.72	0.72	NUM
admet-505	448	102	2.12	2.12	NUM
admet-505	448	103	3.12	3.12	NUM
admet-505	448	104	2.56	2.56	NUM
admet-505	448	105	2.16	2.16	NUM
admet-505	448	106	ph	ph	NOUN
admet-505	448	107	5.0	5.0	NUM
admet-505	448	108	[	[	SYM
admet-505	448	109	51	51	NUM
admet-505	448	110	]	]	X
admet-505	448	111	piroxicam	piroxicam	NOUN
admet-505	448	112	ab	ab	PROPN
admet-505	448	113	1.76	1.76	NUM
admet-505	448	114	4.96	4.96	NUM
admet-505	448	115	37	37	NUM
admet-505	448	116	0.023	0.023	NUM
admet-505	448	117	0.018	0.018	NUM
admet-505	448	118	0.002	0.002	NUM
admet-505	448	119	3	3	NUM
admet-505	448	120	8.8	8.8	NUM
admet-505	448	121	2	2	NUM
admet-505	448	122	0.55	0.55	NUM
admet-505	448	123	1.1	1.1	NUM
admet-505	448	124	1.98	1.98	NUM
admet-505	448	125	-4.33	-4.33	NUM
admet-505	448	126	0.33	0.33	NUM
admet-505	448	127	18	18	NUM
admet-505	448	128	0.72	0.72	NUM
admet-505	448	129	2.12	2.12	NUM
admet-505	448	130	3.12	3.12	NUM
admet-505	448	131	2.56	2.56	NUM
admet-505	448	132	2.16	2.16	NUM
admet-505	448	133	ph	ph	NOUN
admet-505	448	134	6.0	6.0	NUM
admet-505	448	135	[	[	X
admet-505	448	136	51	51	NUM
admet-505	448	137	]	]	PUNCT
admet-505	448	138	piroxicam	piroxicam	NOUN
admet-505	448	139	ab	ab	PROPN
admet-505	448	140	1.76	1.76	NUM
admet-505	448	141	4.96	4.96	NUM
admet-505	448	142	37	37	NUM
admet-505	448	143	0.023	0.023	NUM
admet-505	448	144	0.031	0.031	NUM
admet-505	448	145	0.0004	0.0004	NUM
admet-505	448	146	3	3	NUM
admet-505	448	147	10	10	NUM
admet-505	448	148	2	2	NUM
admet-505	448	149	0.96	0.96	NUM
admet-505	448	150	1.9	1.9	NUM
admet-505	448	151	1.98	1.98	NUM
admet-505	448	152	-4.33	-4.33	NUM
admet-505	448	153	0.33	0.33	NUM
admet-505	448	154	18	18	NUM
admet-505	448	155	0.72	0.72	NUM
admet-505	448	156	2.12	2.12	NUM
admet-505	448	157	3.12	3.12	NUM
admet-505	448	158	2.56	2.56	NUM
admet-505	448	159	2.16	2.16	NUM
admet-505	448	160	ph	ph	NOUN
admet-505	448	161	7.0	7.0	NUM
admet-505	448	162	[	[	X
admet-505	448	163	51	51	NUM
admet-505	448	164	]	]	PUNCT
admet-505	448	165	piroxicam	piroxicam	NOUN
admet-505	448	166	ab	ab	PROPN
admet-505	448	167	1.76	1.76	NUM
admet-505	448	168	4.96	4.96	NUM
admet-505	448	169	37	37	NUM
admet-505	448	170	0.023	0.023	NUM
admet-505	448	171	0.018	0.018	NUM
admet-505	448	172	0.044	0.044	NUM
admet-505	448	173	3	3	NUM
admet-505	448	174	8.8	8.8	NUM
admet-505	448	175	2	2	NUM
admet-505	448	176	0.56	0.56	NUM
admet-505	448	177	1.1	1.1	NUM
admet-505	448	178	1.98	1.98	NUM
admet-505	448	179	-4.33	-4.33	NUM
admet-505	448	180	0.33	0.33	NUM
admet-505	448	181	18	18	NUM
admet-505	448	182	0.72	0.72	NUM
admet-505	448	183	2.12	2.12	NUM
admet-505	448	184	3.12	3.12	NUM
admet-505	448	185	2.56	2.56	NUM
admet-505	448	186	2.16	2.16	NUM
admet-505	448	187	ph	ph	NOUN
admet-505	448	188	7.8	7.8	NUM
admet-505	448	189	[	[	X
admet-505	448	190	51	51	NUM
admet-505	448	191	]	]	PUNCT
admet-505	448	192	prazepam	prazepam	VERB
admet-505	448	193	b	b	PROPN
admet-505	448	194	3.04	3.04	NUM
admet-505	448	195	24	24	NUM
admet-505	448	196	0.199	0.199	NUM
admet-505	448	197	0.154	0.154	NUM
admet-505	448	198	0.005	0.005	NUM
admet-505	448	199	3	3	NUM
admet-505	448	200	37	37	NUM
admet-505	448	201	10	10	NUM
admet-505	448	202	0.96	0.96	NUM
admet-505	448	203	9.6	9.6	NUM
admet-505	448	204	3.73	3.73	NUM
admet-505	448	205	-3.56	-3.56	NUM
admet-505	448	206	0.23	0.23	NUM
admet-505	448	207	2	2	NUM
admet-505	448	208	0.00	0.00	NUM
admet-505	448	209	1.05	1.05	NUM
admet-505	448	210	1.81	1.81	NUM
admet-505	448	211	2.32	2.32	NUM
admet-505	448	212	2.39	2.39	NUM
admet-505	448	213	[	[	X
admet-505	448	214	36	36	NUM
admet-505	448	215	]	]	X
admet-505	448	216	progesterone	progesterone	NOUN
admet-505	448	217	n	n	NOUN
admet-505	448	218	25	25	NUM
admet-505	448	219	0.139	0.139	NUM
admet-505	448	220	0.126	0.126	NUM
admet-505	448	221	0.166	0.166	NUM
admet-505	448	222	7	7	NUM
admet-505	448	223	?	?	SYM
admet-505	448	224	38	38	NUM
admet-505	448	225	8	8	NUM
admet-505	448	226	0.98	0.98	NUM
admet-505	448	227	7.8	7.8	NUM
admet-505	448	228	3.77	3.77	NUM
admet-505	448	229	-4.53	-4.53	NUM
admet-505	448	230	0.22	0.22	NUM
admet-505	448	231	12	12	NUM
admet-505	448	232	0.00	0.00	NUM
admet-505	448	233	1.04	1.04	NUM
admet-505	448	234	2.49	2.49	NUM
admet-505	448	235	1.56	1.56	NUM
admet-505	448	236	2.62	2.62	NUM
admet-505	448	237	[	[	X
admet-505	448	238	40	40	NUM
admet-505	448	239	]	]	PUNCT
admet-505	448	240	progesterone	progesterone	NOUN
admet-505	448	241	n	n	NOUN
admet-505	448	242	24	24	NUM
admet-505	448	243	0.139	0.139	NUM
admet-505	448	244	0.227	0.227	NUM
admet-505	448	245	0.006	0.006	NUM
admet-505	448	246	3	3	NUM
admet-505	448	247	69	69	NUM
admet-505	448	248	15	15	NUM
admet-505	448	249	0.94	0.94	NUM
admet-505	448	250	14.1	14.1	NUM
admet-505	448	251	3.77	3.77	NUM
admet-505	448	252	-4.53	-4.53	NUM
admet-505	448	253	0.22	0.22	NUM
admet-505	448	254	12	12	NUM
admet-505	448	255	0.00	0.00	NUM
admet-505	448	256	1.04	1.04	NUM
admet-505	448	257	2.49	2.49	NUM
admet-505	448	258	1.56	1.56	NUM
admet-505	448	259	2.62	2.62	NUM
admet-505	448	260	[	[	SYM
admet-505	448	261	36	36	NUM
admet-505	448	262	]	]	PUNCT
admet-505	448	263	progesterone	progesterone	NOUN
admet-505	448	264	n	n	NOUN
admet-505	448	265	24	24	NUM
admet-505	448	266	0.139	0.139	NUM
admet-505	448	267	0.150	0.150	NUM
admet-505	448	268	0.001	0.001	NUM
admet-505	448	269	3	3	NUM
admet-505	448	270	46	46	NUM
admet-505	448	271	10	10	NUM
admet-505	448	272	0.93	0.93	NUM
admet-505	448	273	9.3	9.3	NUM
admet-505	448	274	3.77	3.77	NUM
admet-505	448	275	-4.53	-4.53	NUM
admet-505	448	276	0.22	0.22	NUM
admet-505	448	277	12	12	NUM
admet-505	448	278	0.00	0.00	NUM
admet-505	448	279	1.04	1.04	NUM
admet-505	448	280	2.49	2.49	NUM
admet-505	448	281	1.56	1.56	NUM
admet-505	448	282	2.62	2.62	NUM
admet-505	448	283	0.15	0.15	NUM
admet-505	448	284	m	m	NOUN
admet-505	448	285	nacl	nacl	NOUN
admet-505	449	1	[	[	X
admet-505	449	2	36	36	NUM
admet-505	449	3	]	]	PUNCT
admet-505	449	4	progesterone,11	progesterone,11	NOUN
admet-505	449	5	-	-	PUNCT
admet-505	449	6	α	α	X
admet-505	449	7	-	-	PUNCT
admet-505	449	8	hon	hon	NOUN
admet-505	449	9	24	24	NUM
admet-505	449	10	0.122	0.122	NUM
admet-505	449	11	0.276	0.276	NUM
admet-505	449	12	0.007	0.007	NUM
admet-505	449	13	3	3	NUM
admet-505	449	14	82	82	NUM
admet-505	449	15	18	18	NUM
admet-505	449	16	0.95	0.95	NUM
admet-505	449	17	17.1	17.1	NUM
admet-505	449	18	2.36	2.36	NUM
admet-505	449	19	-4.51	-4.51	NUM
admet-505	449	20	0.39	0.39	NUM
admet-505	449	21	5	5	NUM
admet-505	449	22	0.31	0.31	NUM
admet-505	449	23	1.35	1.35	NUM
admet-505	449	24	2.75	2.75	NUM
admet-505	449	25	1.77	1.77	NUM
admet-505	449	26	2.68	2.68	NUM
admet-505	450	1	[	[	X
admet-505	450	2	36	36	NUM
admet-505	450	3	]	]	PUNCT
admet-505	450	4	repaglinide	repaglinide	NOUN
admet-505	450	5	ab	ab	PROPN
admet-505	451	1	3.83	3.83	NUM
admet-505	451	2	6.20	6.20	NUM
admet-505	451	3	25	25	NUM
admet-505	451	4	0.034	0.034	NUM
admet-505	451	5	0.038	0.038	NUM
admet-505	451	6	0.037	0.037	NUM
admet-505	451	7	1	1	NUM
admet-505	451	8	15	15	NUM
admet-505	451	9	3	3	NUM
admet-505	451	10	0.79	0.79	NUM
admet-505	451	11	2.4	2.4	NUM
admet-505	451	12	4.69	4.69	NUM
admet-505	451	13	-4.89	-4.89	NUM
admet-505	451	14	0.16	0.16	NUM
admet-505	451	15	2	2	NUM
admet-505	451	16	0.83	0.83	NUM
admet-505	451	17	1.71	1.71	NUM
admet-505	451	18	2.77	2.77	NUM
admet-505	451	19	2.17	2.17	NUM
admet-505	451	20	3.68	3.68	NUM
admet-505	451	21	[	[	X
admet-505	451	22	39	39	NUM
admet-505	451	23	]	]	PUNCT
admet-505	451	24	repaglinide	repaglinide	NOUN
admet-505	451	25	ab	ab	PROPN
admet-505	451	26	3.83	3.83	NUM
admet-505	451	27	6.20	6.20	NUM
admet-505	451	28	25	25	NUM
admet-505	451	29	0.034	0.034	NUM
admet-505	451	30	0.045	0.045	NUM
admet-505	451	31	0.044	0.044	NUM
admet-505	451	32	1	1	NUM
admet-505	451	33	16	16	NUM
admet-505	451	34	3	3	NUM
admet-505	451	35	0.93	0.93	NUM
admet-505	451	36	2.8	2.8	NUM
admet-505	451	37	4.69	4.69	NUM
admet-505	451	38	-4.89	-4.89	NUM
admet-505	451	39	0.16	0.16	NUM
admet-505	451	40	2	2	NUM
admet-505	451	41	0.83	0.83	NUM
admet-505	451	42	1.71	1.71	NUM
admet-505	451	43	2.77	2.77	NUM
admet-505	451	44	2.17	2.17	NUM
admet-505	451	45	3.68	3.68	NUM
admet-505	451	46	0.15	0.15	NUM
admet-505	451	47	m	m	NOUN
admet-505	451	48	nacl	nacl	NOUN
admet-505	451	49	[	[	X
admet-505	451	50	39	39	NUM
admet-505	451	51	]	]	PUNCT
admet-505	451	52	resveratrol	resveratrol	NOUN
admet-505	451	53	a	a	DET
admet-505	451	54	9.8	9.8	NUM
admet-505	451	55	8.8	8.8	NUM
admet-505	451	56	25	25	NUM
admet-505	451	57	0.097	0.097	NUM
admet-505	451	58	0.032	0.032	NUM
admet-505	451	59	0.002	0.002	NUM
admet-505	451	60	4	4	NUM
admet-505	451	61	9.2	9.2	NUM
admet-505	451	62	2	2	NUM
admet-505	451	63	0.99	0.99	NUM
admet-505	451	64	2.0	2.0	NUM
admet-505	451	65	3.14	3.14	NUM
admet-505	451	66	-3.57	-3.57	NUM
admet-505	451	67	0.18	0.18	NUM
admet-505	451	68	7	7	NUM
admet-505	451	69	1.50	1.50	NUM
admet-505	451	70	1.04	1.04	NUM
admet-505	451	71	1.82	1.82	NUM
admet-505	451	72	1.97	1.97	NUM
admet-505	451	73	1.74	1.74	NUM
admet-505	451	74	ph	ph	NOUN
admet-505	451	75	8.0	8.0	NUM
admet-505	451	76	[	[	X
admet-505	451	77	52	52	NUM
admet-505	451	78	]	]	PUNCT
admet-505	451	79	resveratrol	resveratrol	NOUN
admet-505	451	80	a	a	DET
admet-505	451	81	9.8	9.8	NUM
admet-505	451	82	8.8	8.8	NUM
admet-505	451	83	25	25	NUM
admet-505	451	84	0.097	0.097	NUM
admet-505	451	85	0.023	0.023	NUM
admet-505	451	86	0.001	0.001	NUM
admet-505	451	87	4	4	NUM
admet-505	451	88	7.5	7.5	NUM
admet-505	451	89	2	2	NUM
admet-505	451	90	0.71	0.71	NUM
admet-505	451	91	1.4	1.4	NUM
admet-505	451	92	3.14	3.14	NUM
admet-505	451	93	-3.57	-3.57	NUM
admet-505	451	94	0.18	0.18	NUM
admet-505	451	95	7	7	NUM
admet-505	451	96	1.50	1.50	NUM
admet-505	451	97	1.04	1.04	NUM
admet-505	451	98	1.82	1.82	NUM
admet-505	451	99	1.97	1.97	NUM
admet-505	451	100	1.74	1.74	NUM
admet-505	451	101	ph	ph	NOUN
admet-505	451	102	8.0	8.0	NUM
admet-505	451	103	,	,	PUNCT
admet-505	451	104	0.3	0.3	NUM
admet-505	451	105	m	m	NOUN
admet-505	451	106	nacl	nacl	NOUN
admet-505	452	1	[	[	X
admet-505	452	2	52	52	NUM
admet-505	452	3	]	]	PUNCT
admet-505	452	4	resveratrol	resveratrol	NOUN
admet-505	452	5	a	a	DET
admet-505	452	6	9.8	9.8	NUM
admet-505	452	7	8.8	8.8	NUM
admet-505	452	8	25	25	NUM
admet-505	452	9	0.097	0.097	NUM
admet-505	452	10	0.033	0.033	NUM
admet-505	452	11	0.001	0.001	NUM
admet-505	452	12	4	4	NUM
admet-505	452	13	11	11	NUM
admet-505	452	14	3	3	NUM
admet-505	452	15	0.68	0.68	NUM
admet-505	452	16	2.1	2.1	NUM
admet-505	452	17	3.14	3.14	NUM
admet-505	452	18	-3.57	-3.57	NUM
admet-505	452	19	0.18	0.18	NUM
admet-505	452	20	7	7	NUM
admet-505	452	21	1.50	1.50	NUM
admet-505	452	22	1.04	1.04	NUM
admet-505	452	23	1.82	1.82	NUM
admet-505	452	24	1.97	1.97	NUM
admet-505	452	25	1.74	1.74	NUM
admet-505	452	26	ph	ph	NOUN
admet-505	452	27	8.0	8.0	NUM
admet-505	452	28	,	,	PUNCT
admet-505	452	29	2	2	NUM
admet-505	452	30	m	m	NOUN
admet-505	452	31	urea	urea	NOUN
admet-505	452	32	[	[	X
admet-505	452	33	52	52	NUM
admet-505	452	34	]	]	PUNCT
admet-505	452	35	rosiglitazone	rosiglitazone	NOUN
admet-505	452	36	ab	ab	PROPN
admet-505	452	37	6.23	6.23	NUM
admet-505	452	38	6.51	6.51	NUM
admet-505	452	39	25	25	NUM
admet-505	452	40	0.027	0.027	NUM
admet-505	452	41	0.027	0.027	NUM
admet-505	452	42	0.025	0.025	NUM
admet-505	452	43	1	1	NUM
admet-505	452	44	11	11	NUM
admet-505	452	45	2	2	NUM
admet-505	452	46	0.83	0.83	NUM
admet-505	452	47	1.7	1.7	NUM
admet-505	452	48	2.56	2.56	NUM
admet-505	452	49	-5.05	-5.05	NUM
admet-505	452	50	0.24	0.24	NUM
admet-505	452	51	2	2	NUM
admet-505	452	52	0.34	0.34	NUM
admet-505	452	53	1.88	1.88	NUM
admet-505	452	54	2.64	2.64	NUM
admet-505	452	55	2.55	2.55	NUM
admet-505	452	56	2.61	2.61	NUM
admet-505	452	57	[	[	SYM
admet-505	452	58	39	39	NUM
admet-505	452	59	]	]	PUNCT
admet-505	452	60	admet	admet	PROPN
admet-505	452	61	&	&	CCONJ
admet-505	452	62	dmpk	dmpk	PROPN
admet-505	452	63	6(2	6(2	NUM
admet-505	452	64	)	)	PUNCT
admet-505	452	65	(	(	PUNCT
admet-505	452	66	2018	2018	NUM
admet-505	452	67	)	)	PUNCT
admet-505	452	68	105	105	NUM
admet-505	452	69	-	-	SYM
admet-505	452	70	139	139	NUM
admet-505	452	71	cocrystal	cocrystal	ADJ
admet-505	452	72	solubility	solubility	NOUN
admet-505	452	73	-	-	PUNCT
admet-505	452	74	ph	ph	VERB
admet-505	452	75	,	,	PUNCT
admet-505	452	76	drug	drug	NOUN
admet-505	452	77	solubilization	solubilization	NOUN
admet-505	452	78	capacity	capacity	NOUN
admet-505	452	79	of	of	ADP
admet-505	452	80	sds	sds	PROPN
admet-505	452	81	,	,	PUNCT
admet-505	452	82	mass	mass	ADJ
admet-505	452	83	action	action	NOUN
admet-505	452	84	model	model	NOUN
admet-505	452	85	doi	doi	PROPN
admet-505	452	86	:	:	PUNCT
admet-505	452	87	10.5599	10.5599	NUM
admet-505	452	88	/	/	SYM
admet-505	452	89	admet.505	admet.505	PROPN
admet-505	452	90	117	117	NUM
admet-505	452	91	table	table	NOUN
admet-505	452	92	1	1	NUM
admet-505	452	93	.	.	NUM
admet-505	452	94	continued	continue	VERB
admet-505	452	95	…	…	PUNCT
admet-505	452	96	compound	compound	NOUN
admet-505	452	97	type	type	NOUN
admet-505	452	98	pka	pka	PROPN
admet-505	452	99	(	(	PUNCT
admet-505	452	100	acid	acid	PROPN
admet-505	452	101	)	)	PUNCT
admet-505	452	102	pka	pka	PROPN
admet-505	452	103	(	(	PUNCT
admet-505	452	104	base	base	NOUN
admet-505	452	105	)	)	PUNCT
admet-505	452	106	t(`c	t(`c	PROPN
admet-505	452	107	)	)	PUNCT
admet-505	453	1	k	k	PROPN
admet-505	453	2	(	(	PUNCT
admet-505	453	3	calc	calc	NOUN
admet-505	453	4	)	)	PUNCT
admet-505	453	5	b	b	PROPN
admet-505	454	1	k	k	PROPN
admet-505	454	2	(	(	PUNCT
admet-505	454	3	obs	obs	PROPN
admet-505	454	4	)	)	PUNCT
admet-505	454	5	c	c	PROPN
admet-505	454	6	±	±	NUM
admet-505	454	7	sd	sd	ADP
admet-505	454	8	n	n	PROPN
admet-505	454	9	d	d	NOUN
admet-505	454	10	log	log	NOUN
admet-505	454	11	kn	kn	PROPN
admet-505	454	12	e	e	PROPN
admet-505	454	13	n	n	PROPN
admet-505	454	14	fbm	fbm	NOUN
admet-505	454	15	nd	nd	PRON
admet-505	454	16	log	log	VERB
admet-505	454	17	poct	poct	PROPN
admet-505	454	18	log	log	NOUN
admet-505	454	19	s0	s0	PROPN
admet-505	454	20	±sd	±sd	PROPN
admet-505	454	21	n	n	CCONJ
admet-505	454	22	σα2	σα2	NOUN
admet-505	454	23	h	h	NOUN
admet-505	454	24	σβ2	σβ2	VERB
admet-505	454	25	h	h	PROPN
admet-505	454	26	π2	π2	PROPN
admet-505	454	27	r2	r2	PROPN
admet-505	454	28	vx	vx	ADP
admet-505	454	29	comments	comment	NOUN
admet-505	454	30	ref	ref	PROPN
admet-505	454	31	rosiglitazone	rosiglitazone	NOUN
admet-505	454	32	ab	ab	PROPN
admet-505	454	33	6.23	6.23	NUM
admet-505	454	34	6.51	6.51	NUM
admet-505	454	35	25	25	NUM
admet-505	454	36	0.027	0.027	NUM
admet-505	454	37	0.032	0.032	NUM
admet-505	454	38	0.030	0.030	NUM
admet-505	454	39	1	1	NUM
admet-505	454	40	12	12	NUM
admet-505	454	41	2	2	NUM
admet-505	454	42	1.00	1.00	NUM
admet-505	454	43	2.0	2.0	NUM
admet-505	454	44	2.56	2.56	NUM
admet-505	454	45	-5.05	-5.05	NUM
admet-505	454	46	0.24	0.24	NUM
admet-505	454	47	2	2	NUM
admet-505	454	48	0.34	0.34	NUM
admet-505	454	49	1.88	1.88	NUM
admet-505	454	50	2.64	2.64	NUM
admet-505	454	51	2.55	2.55	NUM
admet-505	454	52	2.61	2.61	NUM
admet-505	454	53	0.15	0.15	NUM
admet-505	454	54	m	m	NOUN
admet-505	454	55	nacl	nacl	NOUN
admet-505	454	56	[	[	X
admet-505	454	57	39	39	NUM
admet-505	454	58	]	]	PUNCT
admet-505	454	59	salicylic	salicylic	NOUN
admet-505	454	60	acid	acid	NOUN
admet-505	454	61	a	a	DET
admet-505	454	62	2.84	2.84	NUM
admet-505	454	63	27	27	NUM
admet-505	454	64	0.467	0.467	NUM
admet-505	454	65	0.544	0.544	NUM
admet-505	454	66	0.066	0.066	NUM
admet-505	454	67	6	6	NUM
admet-505	454	68	65	65	NUM
admet-505	454	69	34	34	NUM
admet-505	454	70	0.99	0.99	NUM
admet-505	454	71	33.7	33.7	NUM
admet-505	454	72	2.19	2.19	NUM
admet-505	454	73	-1.84	-1.84	NOUN
admet-505	454	74	0.07	0.07	NUM
admet-505	454	75	12	12	NUM
admet-505	454	76	0.70	0.70	NUM
admet-505	454	77	0.40	0.40	NUM
admet-505	454	78	1.10	1.10	NUM
admet-505	454	79	0.91	0.91	NUM
admet-505	454	80	0.99	0.99	NUM
admet-505	455	1	[	[	X
admet-505	455	2	44	44	NUM
admet-505	455	3	]	]	PUNCT
admet-505	455	4	temazepam	temazepam	PROPN
admet-505	455	5	b	b	PROPN
admet-505	455	6	1.60	1.60	NUM
admet-505	455	7	24	24	NUM
admet-505	455	8	0.366	0.366	NUM
admet-505	455	9	0.416	0.416	NUM
admet-505	455	10	0.014	0.014	NUM
admet-505	455	11	3	3	NUM
admet-505	455	12	82	82	NUM
admet-505	455	13	26	26	NUM
admet-505	455	14	0.99	0.99	NUM
admet-505	455	15	25.8	25.8	NUM
admet-505	455	16	2.19	2.19	NUM
admet-505	455	17	-3.07	-3.07	NUM
admet-505	455	18	0.54	0.54	NUM
admet-505	455	19	2	2	NUM
admet-505	455	20	0.17	0.17	NUM
admet-505	455	21	1.34	1.34	NUM
admet-505	455	22	1.76	1.76	NUM
admet-505	455	23	2.24	2.24	NUM
admet-505	455	24	2.13	2.13	NUM
admet-505	456	1	[	[	X
admet-505	456	2	36	36	NUM
admet-505	456	3	]	]	PUNCT
admet-505	456	4	testosterone	testosterone	NOUN
admet-505	456	5	n	n	CCONJ
admet-505	457	1	24	24	NUM
admet-505	457	2	0.181	0.181	NUM
admet-505	457	3	0.208	0.208	NUM
admet-505	457	4	0.004	0.004	NUM
admet-505	457	5	3	3	NUM
admet-505	457	6	55	55	NUM
admet-505	457	7	13	13	NUM
admet-505	457	8	0.99	0.99	NUM
admet-505	457	9	12.9	12.9	NUM
admet-505	457	10	3.31	3.31	NUM
admet-505	457	11	-4.09	-4.09	NUM
admet-505	457	12	0.07	0.07	NUM
admet-505	457	13	13	13	NUM
admet-505	457	14	0.31	0.31	NUM
admet-505	457	15	1.01	1.01	NUM
admet-505	457	16	2.27	2.27	NUM
admet-505	457	17	1.55	1.55	NUM
admet-505	457	18	2.38	2.38	NUM
admet-505	457	19	[	[	X
admet-505	457	20	36	36	NUM
admet-505	457	21	]	]	PUNCT
admet-505	457	22	testosterone	testosterone	NOUN
admet-505	457	23	n	n	CCONJ
admet-505	457	24	25	25	NUM
admet-505	457	25	0.181	0.181	NUM
admet-505	457	26	0.115	0.115	NUM
admet-505	457	27	0.060	0.060	NUM
admet-505	457	28	7	7	NUM
admet-505	457	29	?	?	SYM
admet-505	457	30	34	34	NUM
admet-505	457	31	8	8	NUM
admet-505	457	32	0.89	0.89	NUM
admet-505	457	33	7.1	7.1	NUM
admet-505	457	34	3.31	3.31	NUM
admet-505	457	35	-4.09	-4.09	NUM
admet-505	457	36	0.07	0.07	NUM
admet-505	457	37	13	13	NUM
admet-505	457	38	0.31	0.31	NUM
admet-505	457	39	1.01	1.01	NUM
admet-505	457	40	2.27	2.27	NUM
admet-505	457	41	1.55	1.55	NUM
admet-505	457	42	2.38	2.38	NUM
admet-505	457	43	[	[	X
admet-505	457	44	40	40	NUM
admet-505	457	45	]	]	PUNCT
admet-505	457	46	toluic	toluic	PROPN
admet-505	457	47	acid,3a	acid,3a	NOUN
admet-505	457	48	4.26	4.26	NUM
admet-505	457	49	35	35	NUM
admet-505	457	50	0.865	0.865	NUM
admet-505	457	51	1.199	1.199	NUM
admet-505	457	52	0.009	0.009	NUM
admet-505	457	53	6	6	NUM
admet-505	457	54	124	124	NUM
admet-505	457	55	75	75	NUM
admet-505	457	56	0.99	0.99	NUM
admet-505	457	57	74.3	74.3	NUM
admet-505	457	58	2.39	2.39	NUM
admet-505	457	59	-1.63	-1.63	NUM
admet-505	457	60	0.38	0.38	NUM
admet-505	457	61	3	3	NUM
admet-505	457	62	0.57	0.57	NUM
admet-505	457	63	0.44	0.44	NUM
admet-505	457	64	1.02	1.02	NUM
admet-505	457	65	0.77	0.77	NUM
admet-505	457	66	1.07	1.07	NUM
admet-505	457	67	[	[	X
admet-505	457	68	31	31	NUM
admet-505	457	69	]	]	X
admet-505	457	70	toluic	toluic	NOUN
admet-505	457	71	acid,4a	acid,4a	ADP
admet-505	457	72	4.35	4.35	NUM
admet-505	457	73	35	35	NUM
admet-505	457	74	0.545	0.545	NUM
admet-505	457	75	0.375	0.375	NUM
admet-505	457	76	0.006	0.006	NUM
admet-505	457	77	6	6	NUM
admet-505	457	78	52	52	NUM
admet-505	457	79	24	24	NUM
admet-505	457	80	0.97	0.97	NUM
admet-505	457	81	23.2	23.2	NUM
admet-505	457	82	2.29	2.29	NUM
admet-505	457	83	-2.11	-2.11	NUM
admet-505	457	84	0.51	0.51	NUM
admet-505	457	85	5	5	NUM
admet-505	457	86	0.57	0.57	NUM
admet-505	457	87	0.44	0.44	NUM
admet-505	457	88	1.02	1.02	NUM
admet-505	457	89	0.77	0.77	NUM
admet-505	457	90	1.07	1.07	NUM
admet-505	458	1	[	[	X
admet-505	458	2	31	31	NUM
admet-505	458	3	]	]	PUNCT
admet-505	458	4	valsartan	valsartan	VERB
admet-505	458	5	a	a	DET
admet-505	458	6	4.70	4.70	NUM
admet-505	458	7	3.60	3.60	NUM
admet-505	458	8	25	25	NUM
admet-505	458	9	0.087	0.087	NUM
admet-505	458	10	0.313	0.313	NUM
admet-505	458	11	0.005	0.005	NUM
admet-505	458	12	8	8	NUM
admet-505	458	13	75	75	NUM
admet-505	458	14	20	20	NUM
admet-505	458	15	0.97	0.97	NUM
admet-505	458	16	19.4	19.4	NUM
admet-505	458	17	3.90	3.90	NUM
admet-505	458	18	-3.69	-3.69	NUM
admet-505	458	19	0.36	0.36	NUM
admet-505	458	20	4	4	NUM
admet-505	458	21	1.21	1.21	NUM
admet-505	458	22	1.82	1.82	NUM
admet-505	458	23	3.32	3.32	NUM
admet-505	458	24	2.96	2.96	NUM
admet-505	458	25	3.41	3.41	NUM
admet-505	458	26	[	[	X
admet-505	458	27	53	53	NUM
admet-505	458	28	]	]	PUNCT
admet-505	458	29	a	a	DET
admet-505	458	30	kn	kn	PROPN
admet-505	458	31	=	=	NOUN
admet-505	458	32	drug	drug	NOUN
admet-505	458	33	-	-	PUNCT
admet-505	458	34	micelle	micelle	NOUN
admet-505	458	35	binding	bind	VERB
admet-505	458	36	constant	constant	ADJ
admet-505	458	37	,	,	PUNCT
admet-505	458	38	where	where	SCONJ
admet-505	458	39	n	n	NUM
admet-505	458	40	drugs	drug	NOUN
admet-505	458	41	are	be	AUX
admet-505	458	42	bound	bind	VERB
admet-505	458	43	to	to	ADP
admet-505	458	44	one	one	NUM
admet-505	458	45	micelle	micelle	NOUN
admet-505	458	46	;	;	PUNCT
admet-505	458	47	nd	nd	NOUN
admet-505	458	48	=	=	SYM
admet-505	458	49	average	average	ADJ
admet-505	458	50	number	number	NOUN
admet-505	458	51	of	of	ADP
admet-505	458	52	bound	bind	VERB
admet-505	458	53	drugs	drug	NOUN
admet-505	458	54	per	per	ADP
admet-505	458	55	micelle	micelle	NOUN
admet-505	458	56	;	;	PUNCT
admet-505	458	57	fbm	fbm	NOUN
admet-505	458	58	=	=	SYM
admet-505	458	59	fraction	fraction	NOUN
admet-505	458	60	of	of	ADP
admet-505	458	61	drug	drug	NOUN
admet-505	458	62	-	-	PUNCT
admet-505	458	63	bound	bind	VERB
admet-505	458	64	micelles	micelle	NOUN
admet-505	458	65	;	;	PUNCT
admet-505	458	66	poct	poct	NOUN
admet-505	458	67	=	=	SYM
admet-505	458	68	octanol	octanol	NOUN
admet-505	458	69	-	-	PUNCT
admet-505	458	70	water	water	NOUN
admet-505	458	71	partition	partition	NOUN
admet-505	458	72	coefficient	coefficient	NOUN
admet-505	458	73	;	;	PUNCT
admet-505	458	74	s0	s0	PROPN
admet-505	458	75	=	=	PUNCT
admet-505	458	76	intrinsic	intrinsic	ADJ
admet-505	458	77	solubility	solubility	NOUN
admet-505	458	78	,	,	PUNCT
admet-505	458	79	average	average	NOUN
admet-505	458	80	of	of	ADP
admet-505	458	81	n	n	DET
admet-505	458	82	published	publish	VERB
admet-505	458	83	values	value	NOUN
admet-505	458	84	;	;	PUNCT
admet-505	458	85	σα2	σα2	NOUN
admet-505	458	86	h	h	NOUN
admet-505	458	87	,	,	PUNCT
admet-505	458	88	...	...	PUNCT
admet-505	458	89	,	,	PUNCT
admet-505	458	90	vx	vx	X
admet-505	458	91	are	be	AUX
admet-505	458	92	the	the	DET
admet-505	458	93	calculated	calculated	ADJ
admet-505	458	94	abraham	abraham	PROPN
admet-505	458	95	solvation	solvation	NOUN
admet-505	458	96	descriptors	descriptor	NOUN
admet-505	458	97	(	(	PUNCT
admet-505	458	98	cf	cf	NOUN
admet-505	458	99	.	.	PUNCT
admet-505	458	100	,	,	PUNCT
admet-505	458	101	glossary	glossary	NOUN
admet-505	458	102	)	)	PUNCT
admet-505	458	103	.	.	PUNCT
admet-505	459	1	b	b	NOUN
admet-505	459	2	calculated	calculate	VERB
admet-505	459	3	from	from	ADP
admet-505	459	4	expressions	expression	NOUN
admet-505	459	5	in	in	ADP
admet-505	459	6	table	table	NOUN
admet-505	459	7	2	2	NUM
admet-505	459	8	.	.	PUNCT
admet-505	460	1	e	e	NOUN
admet-505	460	2	calculated	calculate	VERB
admet-505	460	3	using	use	VERB
admet-505	460	4	eq	eq	ADP
admet-505	460	5	.	.	PUNCT
admet-505	461	1	(	(	PUNCT
admet-505	461	2	13	13	NUM
admet-505	461	3	)	)	PUNCT
admet-505	461	4	.	.	PUNCT
admet-505	462	1	admet	admet	PROPN
admet-505	462	2	&	&	CCONJ
admet-505	462	3	dmpk	dmpk	PROPN
admet-505	462	4	6(2	6(2	NUM
admet-505	462	5	)	)	PUNCT
admet-505	462	6	(	(	PUNCT
admet-505	462	7	2018	2018	NUM
admet-505	462	8	)	)	PUNCT
admet-505	462	9	105	105	NUM
admet-505	462	10	-	-	SYM
admet-505	462	11	139	139	NUM
admet-505	462	12	cocrystal	cocrystal	ADJ
admet-505	462	13	solubility	solubility	NOUN
admet-505	462	14	-	-	PUNCT
admet-505	462	15	ph	ph	VERB
admet-505	462	16	,	,	PUNCT
admet-505	462	17	drug	drug	NOUN
admet-505	462	18	solubilization	solubilization	NOUN
admet-505	462	19	capacity	capacity	NOUN
admet-505	462	20	of	of	ADP
admet-505	462	21	sds	sds	PROPN
admet-505	462	22	,	,	PUNCT
admet-505	462	23	mass	mass	ADJ
admet-505	462	24	action	action	NOUN
admet-505	462	25	model	model	NOUN
admet-505	462	26	doi	doi	PROPN
admet-505	462	27	:	:	PUNCT
admet-505	462	28	10.5599	10.5599	NUM
admet-505	462	29	/	/	SYM
admet-505	462	30	admet.505	admet.505	PROPN
admet-505	462	31	118	118	NUM
admet-505	462	32	with	with	ADP
admet-505	462	33	water	water	NOUN
admet-505	462	34	solubility	solubility	NOUN
admet-505	462	35	determined	determine	VERB
admet-505	462	36	from	from	ADP
admet-505	462	37	the	the	DET
admet-505	462	38	horizontal	horizontal	ADJ
admet-505	462	39	portions	portion	NOUN
admet-505	462	40	of	of	ADP
admet-505	462	41	the	the	DET
admet-505	462	42	curves	curve	NOUN
admet-505	462	43	(	(	PUNCT
admet-505	462	44	or	or	CCONJ
admet-505	462	45	taken	take	VERB
admet-505	462	46	from	from	ADP
admet-505	462	47	literature	literature	NOUN
admet-505	462	48	sources	source	NOUN
admet-505	462	49	)	)	PUNCT
admet-505	462	50	,	,	PUNCT
admet-505	462	51	and	and	CCONJ
admet-505	462	52	with	with	ADP
admet-505	462	53	the	the	DET
admet-505	462	54	k	k	PROPN
admet-505	462	55	values	value	NOUN
admet-505	462	56	determined	determine	VERB
admet-505	462	57	from	from	ADP
admet-505	462	58	the	the	DET
admet-505	462	59	micellar	micellar	ADJ
admet-505	462	60	portions	portion	NOUN
admet-505	462	61	of	of	ADP
admet-505	462	62	the	the	DET
admet-505	462	63	plots	plot	NOUN
admet-505	462	64	,	,	PUNCT
admet-505	462	65	it	it	PRON
admet-505	462	66	was	be	AUX
admet-505	462	67	possible	possible	ADJ
admet-505	462	68	to	to	PART
admet-505	462	69	approximate	approximate	VERB
admet-505	462	70	the	the	DET
admet-505	462	71	drug	drug	NOUN
admet-505	462	72	-	-	PUNCT
admet-505	462	73	micelle	micelle	NOUN
admet-505	462	74	binding	binding	ADJ
admet-505	462	75	constants	constant	NOUN
admet-505	462	76	,	,	PUNCT
admet-505	462	77	log	log	PROPN
admet-505	462	78	kn	kn	PROPN
admet-505	462	79	,	,	PUNCT
admet-505	462	80	according	accord	VERB
admet-505	462	81	to	to	ADP
admet-505	462	82	eq	eq	PROPN
admet-505	462	83	.	.	PUNCT
admet-505	463	1	(	(	PUNCT
admet-505	463	2	13	13	NUM
admet-505	463	3	)	)	PUNCT
admet-505	463	4	.	.	PUNCT
admet-505	464	1	the	the	DET
admet-505	464	2	stoichiometric	stoichiometric	ADJ
admet-505	464	3	coefficient	coefficient	NOUN
admet-505	464	4	,	,	PUNCT
admet-505	464	5	n	n	CCONJ
admet-505	464	6	,	,	PUNCT
admet-505	464	7	was	be	AUX
admet-505	464	8	selected	select	VERB
admet-505	464	9	according	accord	VERB
admet-505	464	10	to	to	ADP
admet-505	464	11	eq	eq	PROPN
admet-505	464	12	.	.	PUNCT
admet-505	465	1	(	(	PUNCT
admet-505	465	2	14	14	NUM
admet-505	465	3	)	)	PUNCT
admet-505	465	4	.	.	PUNCT
admet-505	466	1	these	these	DET
admet-505	466	2	estimated	estimate	VERB
admet-505	466	3	results	result	NOUN
admet-505	466	4	are	be	AUX
admet-505	466	5	listed	list	VERB
admet-505	466	6	in	in	ADP
admet-505	466	7	table	table	NOUN
admet-505	466	8	1	1	NUM
admet-505	466	9	.	.	PUNCT
admet-505	466	10	prediction	prediction	NOUN
admet-505	466	11	model	model	NOUN
admet-505	466	12	for	for	ADP
admet-505	466	13	k	k	PROPN
admet-505	466	14	values	value	NOUN
admet-505	466	15	in	in	ADP
admet-505	466	16	a	a	DET
admet-505	466	17	comprehensive	comprehensive	ADJ
admet-505	466	18	study	study	NOUN
admet-505	466	19	,	,	PUNCT
admet-505	466	20	abraham	abraham	PROPN
admet-505	466	21	et	et	PROPN
admet-505	466	22	al	al	PROPN
admet-505	466	23	.	.	PUNCT
admet-505	467	1	[	[	X
admet-505	467	2	58	58	NUM
admet-505	467	3	]	]	PUNCT
admet-505	467	4	considered	consider	VERB
admet-505	467	5	the	the	DET
admet-505	467	6	sds	sds	NOUN
admet-505	467	7	-	-	PUNCT
admet-505	467	8	water	water	NOUN
admet-505	467	9	partitioning	partitioning	NOUN
admet-505	467	10	of	of	ADP
admet-505	467	11	a	a	DET
admet-505	467	12	large	large	ADJ
admet-505	467	13	number	number	NOUN
admet-505	467	14	of	of	ADP
admet-505	467	15	molecules	molecule	NOUN
admet-505	467	16	(	(	PUNCT
admet-505	467	17	e.g.	e.g.	ADV
admet-505	467	18	,	,	PUNCT
admet-505	467	19	gases	gas	NOUN
admet-505	467	20	,	,	PUNCT
admet-505	467	21	common	common	ADJ
admet-505	467	22	solvents	solvent	NOUN
admet-505	467	23	,	,	PUNCT
admet-505	467	24	polycyclic	polycyclic	NOUN
admet-505	467	25	aromatics	aromatic	NOUN
admet-505	467	26	,	,	PUNCT
admet-505	467	27	carboxylic	carboxylic	ADJ
admet-505	467	28	acid	acid	NOUN
admet-505	467	29	and	and	CCONJ
admet-505	467	30	phenol	phenol	ADJ
admet-505	467	31	derivatives	derivative	NOUN
admet-505	467	32	,	,	PUNCT
admet-505	467	33	etc	etc	X
admet-505	467	34	.	.	X
admet-505	467	35	)	)	PUNCT
admet-505	467	36	and	and	CCONJ
admet-505	467	37	developed	develop	VERB
admet-505	467	38	tight	tight	ADJ
admet-505	467	39	prediction	prediction	NOUN
admet-505	467	40	equations	equation	NOUN
admet-505	467	41	based	base	VERB
admet-505	467	42	on	on	ADP
admet-505	467	43	octanol	octanol	NOUN
admet-505	467	44	-	-	PUNCT
admet-505	467	45	water	water	NOUN
admet-505	467	46	partition	partition	NOUN
admet-505	467	47	coefficients	coefficient	NOUN
admet-505	467	48	,	,	PUNCT
admet-505	467	49	as	as	ADV
admet-505	467	50	well	well	ADV
admet-505	467	51	as	as	ADP
admet-505	467	52	the	the	DET
admet-505	467	53	five	five	NUM
admet-505	467	54	abraham	abraham	PROPN
admet-505	467	55	solvation	solvation	NOUN
admet-505	467	56	descriptors	descriptor	NOUN
admet-505	467	57	(	(	PUNCT
admet-505	467	58	r	r	NOUN
admet-505	467	59	2	2	NUM
admet-505	467	60	=	=	SYM
admet-505	467	61	0.97	0.97	NUM
admet-505	467	62	,	,	PUNCT
admet-505	467	63	sd	sd	ADP
admet-505	467	64	=	=	SYM
admet-505	467	65	0.17	0.17	NUM
admet-505	467	66	log	log	NOUN
admet-505	467	67	unit	unit	NOUN
admet-505	467	68	,	,	PUNCT
admet-505	467	69	f	f	PROPN
admet-505	467	70	=	=	SYM
admet-505	467	71	817	817	NUM
admet-505	467	72	,	,	PUNCT
admet-505	467	73	n	n	NOUN
admet-505	467	74	=	=	NUM
admet-505	467	75	132	132	NUM
admet-505	467	76	)	)	PUNCT
admet-505	467	77	.	.	PUNCT
admet-505	468	1	the	the	DET
admet-505	468	2	micelles	micelle	NOUN
admet-505	468	3	were	be	AUX
admet-505	468	4	treated	treat	VERB
admet-505	468	5	as	as	ADP
admet-505	468	6	a	a	DET
admet-505	468	7	separate	separate	ADJ
admet-505	468	8	phase	phase	NOUN
admet-505	468	9	in	in	ADP
admet-505	468	10	the	the	DET
admet-505	468	11	two	two	NUM
admet-505	468	12	-	-	PUNCT
admet-505	468	13	phase	phase	NOUN
admet-505	468	14	(	(	PUNCT
admet-505	468	15	aqueous	aqueous	ADJ
admet-505	468	16	-	-	PUNCT
admet-505	468	17	micellar	micellar	NOUN
admet-505	468	18	)	)	PUNCT
admet-505	468	19	media	medium	NOUN
admet-505	468	20	.	.	PUNCT
admet-505	469	1	the	the	DET
admet-505	469	2	sds	sds	PROPN
admet-505	469	3	-	-	PUNCT
admet-505	469	4	water	water	NOUN
admet-505	469	5	partition	partition	NOUN
admet-505	469	6	coefficients	coefficient	NOUN
admet-505	469	7	,	,	PUNCT
admet-505	469	8	psds	psds	NOUN
admet-505	469	9	-	-	PUNCT
admet-505	469	10	water	water	NOUN
admet-505	469	11	,	,	PUNCT
admet-505	469	12	can	can	AUX
admet-505	469	13	be	be	AUX
admet-505	469	14	converted	convert	VERB
admet-505	469	15	into	into	ADP
admet-505	469	16	k	k	PROPN
admet-505	469	17	values	value	NOUN
admet-505	469	18	,	,	PUNCT
admet-505	469	19	as	as	SCONJ
admet-505	469	20	mentioned	mention	VERB
admet-505	469	21	above	above	ADP
admet-505	469	22	[	[	X
admet-505	469	23	12	12	NUM
admet-505	469	24	]	]	PUNCT
admet-505	469	25	.	.	PUNCT
admet-505	470	1	apparently	apparently	ADV
admet-505	470	2	,	,	PUNCT
admet-505	470	3	the	the	DET
admet-505	470	4	prediction	prediction	NOUN
admet-505	470	5	study	study	NOUN
admet-505	470	6	had	have	AUX
admet-505	470	7	not	not	PART
admet-505	470	8	been	be	AUX
admet-505	470	9	extended	extend	VERB
admet-505	470	10	to	to	ADP
admet-505	470	11	drug	drug	NOUN
admet-505	470	12	molecules	molecule	NOUN
admet-505	470	13	which	which	PRON
admet-505	470	14	precipitate	precipitate	VERB
admet-505	470	15	in	in	ADP
admet-505	470	16	sds	sds	PROPN
admet-505	470	17	-	-	PUNCT
admet-505	470	18	containing	contain	VERB
admet-505	470	19	solutions	solution	NOUN
admet-505	470	20	to	to	PART
admet-505	470	21	form	form	VERB
admet-505	470	22	three	three	NUM
admet-505	470	23	-	-	PUNCT
admet-505	470	24	pseudophase	pseudophase	NOUN
admet-505	470	25	systems	system	NOUN
admet-505	470	26	(	(	PUNCT
admet-505	470	27	aqueous	aqueous	ADJ
admet-505	470	28	,	,	PUNCT
admet-505	470	29	solid	solid	ADJ
admet-505	470	30	,	,	PUNCT
admet-505	470	31	micellar	micellar	NOUN
admet-505	470	32	)	)	PUNCT
admet-505	470	33	.	.	PUNCT
admet-505	471	1	by	by	ADP
admet-505	471	2	contrast	contrast	NOUN
admet-505	471	3	,	,	PUNCT
admet-505	471	4	attention	attention	NOUN
admet-505	471	5	in	in	ADP
admet-505	471	6	the	the	DET
admet-505	471	7	present	present	ADJ
admet-505	471	8	study	study	NOUN
admet-505	471	9	was	be	AUX
admet-505	471	10	directed	direct	VERB
admet-505	471	11	mainly	mainly	ADV
admet-505	471	12	towards	towards	ADP
admet-505	471	13	poorly	poorly	ADV
admet-505	471	14	-	-	PUNCT
admet-505	471	15	soluble	soluble	ADJ
admet-505	471	16	drug	drug	NOUN
admet-505	471	17	molecules	molecule	NOUN
admet-505	471	18	(	(	PUNCT
admet-505	471	19	table	table	NOUN
admet-505	471	20	1	1	NUM
admet-505	471	21	)	)	PUNCT
admet-505	471	22	.	.	PUNCT
admet-505	472	1	as	as	SCONJ
admet-505	472	2	the	the	DET
admet-505	472	3	discussion	discussion	NOUN
admet-505	472	4	has	have	AUX
admet-505	472	5	stressed	stress	VERB
admet-505	472	6	,	,	PUNCT
admet-505	472	7	a	a	DET
admet-505	472	8	drug	drug	NOUN
admet-505	472	9	-	-	PUNCT
admet-505	472	10	micelle	micelle	NOUN
admet-505	472	11	binding	bind	VERB
admet-505	472	12	paradigm	paradigm	NOUN
admet-505	472	13	(	(	PUNCT
admet-505	472	14	i.e.	i.e.	X
admet-505	472	15	,	,	PUNCT
admet-505	472	16	mass	mass	ADJ
admet-505	472	17	action	action	NOUN
admet-505	472	18	model	model	NOUN
admet-505	472	19	)	)	PUNCT
admet-505	472	20	is	be	AUX
admet-505	472	21	used	use	VERB
admet-505	472	22	here	here	ADV
admet-505	472	23	,	,	PUNCT
admet-505	472	24	rather	rather	ADV
admet-505	472	25	than	than	ADP
admet-505	472	26	a	a	DET
admet-505	472	27	partitioning	partition	VERB
admet-505	472	28	approach	approach	NOUN
admet-505	472	29	chosen	choose	VERB
admet-505	472	30	by	by	ADP
admet-505	472	31	abraham	abraham	PROPN
admet-505	472	32	et	et	PROPN
admet-505	472	33	al	al	PROPN
admet-505	472	34	.	.	PUNCT
admet-505	473	1	[	[	X
admet-505	473	2	58	58	NUM
admet-505	473	3	]	]	PUNCT
admet-505	473	4	.	.	PUNCT
admet-505	474	1	several	several	ADJ
admet-505	474	2	comparisons	comparison	NOUN
admet-505	474	3	were	be	AUX
admet-505	474	4	made	make	VERB
admet-505	474	5	in	in	ADP
admet-505	474	6	an	an	DET
admet-505	474	7	attempt	attempt	NOUN
admet-505	474	8	to	to	PART
admet-505	474	9	find	find	VERB
admet-505	474	10	predictive	predictive	ADJ
admet-505	474	11	correlations	correlation	NOUN
admet-505	474	12	between	between	ADP
admet-505	474	13	k	k	PROPN
admet-505	474	14	and	and	CCONJ
admet-505	474	15	other	other	ADJ
admet-505	474	16	commonly	commonly	ADV
admet-505	474	17	-	-	PUNCT
admet-505	474	18	available	available	ADJ
admet-505	474	19	physicochemical	physicochemical	ADJ
admet-505	474	20	descriptors	descriptor	NOUN
admet-505	474	21	.	.	PUNCT
admet-505	475	1	figure	figure	NOUN
admet-505	475	2	8a	8a	PROPN
admet-505	475	3	shows	show	VERB
admet-505	475	4	the	the	DET
admet-505	475	5	plot	plot	NOUN
admet-505	475	6	of	of	ADP
admet-505	475	7	measured	measure	VERB
admet-505	475	8	log	log	NOUN
admet-505	475	9	k	k	PROPN
admet-505	475	10	values	value	NOUN
admet-505	475	11	as	as	ADP
admet-505	475	12	a	a	DET
admet-505	475	13	function	function	NOUN
admet-505	475	14	of	of	ADP
admet-505	475	15	octanol	octanol	NOUN
admet-505	475	16	-	-	PUNCT
admet-505	475	17	water	water	NOUN
admet-505	475	18	partition	partition	NOUN
admet-505	475	19	coefficients	coefficient	NOUN
admet-505	475	20	,	,	PUNCT
admet-505	475	21	log	log	PROPN
admet-505	475	22	poct	poct	NOUN
admet-505	475	23	.	.	PUNCT
admet-505	476	1	the	the	DET
admet-505	476	2	trend	trend	NOUN
admet-505	476	3	suggests	suggest	VERB
admet-505	476	4	that	that	SCONJ
admet-505	476	5	solubilization	solubilization	NOUN
admet-505	476	6	capacity	capacity	NOUN
admet-505	476	7	of	of	ADP
admet-505	476	8	drugs	drug	NOUN
admet-505	476	9	decreases	decrease	VERB
admet-505	476	10	as	as	ADP
admet-505	476	11	lipophilicity	lipophilicity	NOUN
admet-505	476	12	increases	increase	NOUN
admet-505	476	13	,	,	PUNCT
admet-505	476	14	but	but	CCONJ
admet-505	476	15	the	the	DET
admet-505	476	16	correlation	correlation	NOUN
admet-505	476	17	is	be	AUX
admet-505	476	18	clearly	clearly	ADV
admet-505	476	19	weak	weak	ADJ
admet-505	476	20	.	.	PUNCT
admet-505	477	1	a	a	DET
admet-505	477	2	similar	similar	ADJ
admet-505	477	3	trend	trend	NOUN
admet-505	477	4	,	,	PUNCT
admet-505	477	5	albeit	albeit	SCONJ
admet-505	477	6	with	with	ADP
admet-505	477	7	only	only	ADV
admet-505	477	8	slightly	slightly	ADV
admet-505	477	9	improved	improve	VERB
admet-505	477	10	correlation	correlation	NOUN
admet-505	477	11	,	,	PUNCT
admet-505	477	12	is	be	AUX
admet-505	477	13	noted	note	VERB
admet-505	477	14	when	when	SCONJ
admet-505	477	15	log	log	PROPN
admet-505	477	16	k	k	PROPN
admet-505	477	17	is	be	AUX
admet-505	477	18	plotted	plot	VERB
admet-505	477	19	against	against	ADP
admet-505	477	20	size	size	NOUN
admet-505	477	21	of	of	ADP
admet-505	477	22	molecules	molecule	NOUN
admet-505	477	23	in	in	ADP
admet-505	477	24	figure	figure	NOUN
admet-505	477	25	8b	8b	NUM
admet-505	477	26	.	.	PUNCT
admet-505	478	1	for	for	ADP
admet-505	478	2	smaller	small	ADJ
admet-505	478	3	sets	set	NOUN
admet-505	478	4	of	of	ADP
admet-505	478	5	homologous	homologous	ADJ
admet-505	478	6	compounds	compound	NOUN
admet-505	478	7	,	,	PUNCT
admet-505	478	8	better	well	ADJ
admet-505	478	9	correlations	correlation	NOUN
admet-505	478	10	have	have	AUX
admet-505	478	11	been	be	AUX
admet-505	478	12	observed	observe	VERB
admet-505	478	13	.	.	PUNCT
admet-505	479	1	for	for	ADP
admet-505	479	2	example	example	NOUN
admet-505	479	3	,	,	PUNCT
admet-505	479	4	fahelelbom	fahelelbom	ADJ
admet-505	479	5	et	et	PROPN
admet-505	479	6	al	al	PROPN
admet-505	479	7	.	.	PUNCT
admet-505	480	1	[	[	X
admet-505	480	2	30	30	NUM
admet-505	480	3	]	]	PUNCT
admet-505	480	4	reported	report	VERB
admet-505	480	5	r2	r2	PROPN
admet-505	480	6	=	=	PUNCT
admet-505	480	7	0.85	0.85	NUM
admet-505	480	8	for	for	ADP
admet-505	480	9	the	the	DET
admet-505	480	10	correlation	correlation	NOUN
admet-505	480	11	between	between	ADP
admet-505	480	12	k	k	PROPN
admet-505	480	13	and	and	CCONJ
admet-505	480	14	molar	molar	ADJ
admet-505	480	15	volume	volume	NOUN
admet-505	480	16	for	for	ADP
admet-505	480	17	six	six	NUM
admet-505	480	18	iminophenazine	iminophenazine	ADJ
admet-505	480	19	derivatives	derivative	NOUN
admet-505	480	20	(	(	PUNCT
admet-505	480	21	cf	cf	NOUN
admet-505	480	22	.	.	NOUN
admet-505	480	23	,	,	PUNCT
admet-505	480	24	six	six	NUM
admet-505	480	25	squares	square	NOUN
admet-505	480	26	for	for	ADP
admet-505	480	27	log	log	NOUN
admet-505	480	28	k	k	PROPN
admet-505	480	29	<	<	X
admet-505	480	30	-3	-3	X
admet-505	480	31	in	in	ADP
admet-505	480	32	fig	fig	NOUN
admet-505	480	33	.	.	PUNCT
admet-505	481	1	8b	8b	NUM
admet-505	481	2	)	)	PUNCT
admet-505	481	3	.	.	PUNCT
admet-505	482	1	admet	admet	PROPN
admet-505	482	2	&	&	CCONJ
admet-505	482	3	dmpk	dmpk	PROPN
admet-505	482	4	6(2	6(2	NUM
admet-505	482	5	)	)	PUNCT
admet-505	482	6	(	(	PUNCT
admet-505	482	7	2018	2018	NUM
admet-505	482	8	)	)	PUNCT
admet-505	482	9	105	105	NUM
admet-505	482	10	-	-	SYM
admet-505	482	11	139	139	NUM
admet-505	482	12	cocrystal	cocrystal	ADJ
admet-505	482	13	solubility	solubility	NOUN
admet-505	482	14	-	-	PUNCT
admet-505	482	15	ph	ph	VERB
admet-505	482	16	,	,	PUNCT
admet-505	482	17	drug	drug	NOUN
admet-505	482	18	solubilization	solubilization	NOUN
admet-505	482	19	capacity	capacity	NOUN
admet-505	482	20	of	of	ADP
admet-505	482	21	sds	sds	PROPN
admet-505	482	22	,	,	PUNCT
admet-505	482	23	mass	mass	ADJ
admet-505	482	24	action	action	NOUN
admet-505	482	25	model	model	NOUN
admet-505	482	26	doi	doi	PROPN
admet-505	482	27	:	:	PUNCT
admet-505	482	28	10.5599	10.5599	NUM
admet-505	482	29	/	/	SYM
admet-505	482	30	admet.505	admet.505	PROPN
admet-505	482	31	119	119	NUM
admet-505	482	32	figure	figure	NOUN
admet-505	482	33	2	2	NUM
admet-505	482	34	.	.	PUNCT
admet-505	482	35	examples	example	NOUN
admet-505	482	36	of	of	ADP
admet-505	482	37	micellization	micellization	NOUN
admet-505	482	38	plots	plot	NOUN
admet-505	482	39	of	of	ADP
admet-505	482	40	nonionizable	nonionizable	ADJ
admet-505	482	41	drugs	drug	NOUN
admet-505	482	42	.	.	PUNCT
admet-505	483	1	the	the	DET
admet-505	483	2	cmc	cmc	PROPN
admet-505	483	3	values	value	NOUN
admet-505	483	4	span	span	VERB
admet-505	483	5	from	from	ADP
admet-505	483	6	4.6	4.6	NUM
admet-505	483	7	to	to	ADP
admet-505	483	8	9.6	9.6	NUM
admet-505	483	9	mm	mm	NOUN
admet-505	483	10	,	,	PUNCT
admet-505	483	11	which	which	PRON
admet-505	483	12	suggests	suggest	VERB
admet-505	483	13	that	that	SCONJ
admet-505	483	14	the	the	DET
admet-505	483	15	drugs	drug	NOUN
admet-505	483	16	had	have	VERB
admet-505	483	17	only	only	ADV
admet-505	483	18	a	a	DET
admet-505	483	19	small	small	ADJ
admet-505	483	20	influence	influence	NOUN
admet-505	483	21	on	on	ADP
admet-505	483	22	the	the	DET
admet-505	483	23	onset	onset	NOUN
admet-505	483	24	of	of	ADP
admet-505	483	25	micelle	micelle	NOUN
admet-505	483	26	formation	formation	NOUN
admet-505	483	27	with	with	ADP
admet-505	483	28	increasing	increase	VERB
admet-505	483	29	sds	sds	PROPN
admet-505	483	30	additions	addition	NOUN
admet-505	483	31	to	to	ADP
admet-505	483	32	distilled	distil	VERB
admet-505	483	33	water	water	NOUN
admet-505	483	34	.	.	PUNCT
admet-505	484	1	the	the	DET
admet-505	484	2	[	[	X
admet-505	484	3	sds	sds	X
admet-505	484	4	]	]	PUNCT
admet-505	484	5	>	>	X
admet-505	484	6	cmc	cmc	PROPN
admet-505	484	7	curves	curve	NOUN
admet-505	484	8	show	show	VERB
admet-505	484	9	slight	slight	ADJ
admet-505	484	10	curvature	curvature	NOUN
admet-505	484	11	for	for	ADP
admet-505	484	12	artemisinin	artemisinin	NOUN
admet-505	484	13	,	,	PUNCT
admet-505	484	14	carbamazepine	carbamazepine	NOUN
admet-505	484	15	,	,	PUNCT
admet-505	484	16	and	and	CCONJ
admet-505	484	17	fenofibrate	fenofibrate	NOUN
admet-505	484	18	.	.	PUNCT
admet-505	485	1	these	these	PRON
admet-505	485	2	are	be	AUX
admet-505	485	3	the	the	DET
admet-505	485	4	cases	case	NOUN
admet-505	485	5	of	of	ADP
admet-505	485	6	[	[	X
admet-505	485	7	sds	sds	X
admet-505	485	8	]	]	PUNCT
admet-505	485	9	exceeding	exceed	VERB
admet-505	485	10	40	40	NUM
admet-505	485	11	mm	mm	NOUN
admet-505	485	12	,	,	PUNCT
admet-505	485	13	which	which	PRON
admet-505	485	14	may	may	AUX
admet-505	485	15	suggest	suggest	VERB
admet-505	485	16	a	a	DET
admet-505	485	17	saturation	saturation	NOUN
admet-505	485	18	/	/	SYM
admet-505	485	19	decrease	decrease	NOUN
admet-505	485	20	of	of	ADP
admet-505	485	21	the	the	DET
admet-505	485	22	capacity	capacity	NOUN
admet-505	485	23	to	to	PART
admet-505	485	24	bind	bind	VERB
admet-505	485	25	these	these	DET
admet-505	485	26	uncharged	uncharged	ADJ
admet-505	485	27	drugs	drug	NOUN
admet-505	485	28	.	.	PUNCT
admet-505	486	1	the	the	DET
admet-505	486	2	n	n	PROPN
admet-505	486	3	values	value	NOUN
admet-505	486	4	in	in	ADP
admet-505	486	5	table	table	NOUN
admet-505	486	6	1	1	NUM
admet-505	486	7	indicate	indicate	VERB
admet-505	486	8	that	that	SCONJ
admet-505	486	9	19	19	NUM
admet-505	486	10	-	-	SYM
admet-505	486	11	22	22	NUM
admet-505	486	12	carbamazepine	carbamazepine	NOUN
admet-505	486	13	molecules	molecule	NOUN
admet-505	486	14	bind	bind	VERB
admet-505	486	15	to	to	ADP
admet-505	486	16	a	a	DET
admet-505	486	17	single	single	ADJ
admet-505	486	18	micelle	micelle	NOUN
admet-505	486	19	above	above	ADP
admet-505	486	20	the	the	DET
admet-505	486	21	cmc	cmc	NOUN
admet-505	486	22	.	.	PUNCT
admet-505	487	1	the	the	DET
admet-505	487	2	n	n	PROPN
admet-505	487	3	values	value	NOUN
admet-505	487	4	for	for	ADP
admet-505	487	5	artemisinin	artemisinin	NOUN
admet-505	487	6	,	,	PUNCT
admet-505	487	7	11α	11α	NOUN
admet-505	487	8	-	-	PUNCT
admet-505	487	9	hydroxyprogesterone	hydroxyprogesterone	NOUN
admet-505	487	10	,	,	PUNCT
admet-505	487	11	and	and	CCONJ
admet-505	487	12	testosterone	testosterone	NOUN
admet-505	487	13	are	be	AUX
admet-505	487	14	estimated	estimate	VERB
admet-505	487	15	to	to	PART
admet-505	487	16	be	be	AUX
admet-505	487	17	12	12	NUM
admet-505	487	18	,	,	PUNCT
admet-505	487	19	18	18	NUM
admet-505	487	20	,	,	PUNCT
admet-505	487	21	and	and	CCONJ
admet-505	487	22	13	13	NUM
admet-505	487	23	,	,	PUNCT
admet-505	487	24	respectively	respectively	ADV
admet-505	487	25	.	.	PUNCT
admet-505	488	1	just	just	ADV
admet-505	488	2	3	3	NUM
admet-505	488	3	fenofibrate	fenofibrate	NOUN
admet-505	488	4	bind	bind	VERB
admet-505	488	5	to	to	ADP
admet-505	488	6	one	one	NUM
admet-505	488	7	sds	sds	NOUN
admet-505	488	8	micelle	micelle	NOUN
admet-505	488	9	,	,	PUNCT
admet-505	488	10	given	give	VERB
admet-505	488	11	that	that	SCONJ
admet-505	488	12	the	the	DET
admet-505	488	13	drug	drug	NOUN
admet-505	488	14	is	be	AUX
admet-505	488	15	so	so	ADV
admet-505	488	16	poorly	poorly	ADV
admet-505	488	17	soluble	soluble	ADJ
admet-505	488	18	(	(	PUNCT
admet-505	488	19	0.0013	0.0013	NUM
admet-505	488	20	mm	mm	NOUN
admet-505	488	21	)	)	PUNCT
admet-505	488	22	.	.	PUNCT
admet-505	489	1	the	the	DET
admet-505	489	2	solubility	solubility	NOUN
admet-505	489	3	of	of	ADP
admet-505	489	4	the	the	DET
admet-505	489	5	other	other	ADJ
admet-505	489	6	drugs	drug	NOUN
admet-505	489	7	ranges	range	VERB
admet-505	489	8	from	from	ADP
admet-505	489	9	0.03	0.03	NUM
admet-505	489	10	to	to	ADP
admet-505	489	11	0.93	0.93	NUM
admet-505	489	12	mm	mm	NOUN
admet-505	489	13	.	.	PUNCT
admet-505	490	1	the	the	DET
admet-505	490	2	drug	drug	NOUN
admet-505	490	3	-	-	PUNCT
admet-505	490	4	micelle	micelle	NOUN
admet-505	490	5	binding	bind	VERB
admet-505	490	6	constants	constant	NOUN
admet-505	490	7	,	,	PUNCT
admet-505	490	8	kn	kn	PROPN
admet-505	490	9	(	(	PUNCT
admet-505	490	10	cf	cf	NOUN
admet-505	490	11	.	.	NOUN
admet-505	490	12	,	,	PUNCT
admet-505	490	13	eq	eq	NOUN
admet-505	490	14	.	.	PUNCT
admet-505	490	15	(	(	PUNCT
admet-505	490	16	13	13	NUM
admet-505	490	17	)	)	PUNCT
admet-505	490	18	)	)	PUNCT
admet-505	490	19	,	,	PUNCT
admet-505	490	20	range	range	VERB
admet-505	490	21	from	from	ADP
admet-505	490	22	10	10	NUM
admet-505	490	23	+18	+18	ADJ
admet-505	490	24	(	(	PUNCT
admet-505	490	25	fenofibrate	fenofibrate	NOUN
admet-505	490	26	)	)	PUNCT
admet-505	490	27	to	to	ADP
admet-505	490	28	10	10	NUM
admet-505	490	29	+82	+82	NOUN
admet-505	490	30	m	m	VERB
admet-505	490	31	-n	-n	X
admet-505	490	32	(	(	PUNCT
admet-505	490	33	11α	11α	NOUN
admet-505	490	34	-	-	PUNCT
admet-505	490	35	hydroxyprogesterone	hydroxyprogesterone	NOUN
admet-505	490	36	)	)	PUNCT
admet-505	490	37	.	.	PUNCT
admet-505	491	1	pure	pure	ADJ
admet-505	491	2	carbamazepine	carbamazepine	NOUN
admet-505	491	3	or	or	CCONJ
admet-505	491	4	carbamazepine	carbamazepine	NOUN
admet-505	491	5	released	release	VERB
admet-505	491	6	from	from	ADP
admet-505	491	7	cocrystals	cocrystal	NOUN
admet-505	491	8	appears	appear	VERB
admet-505	491	9	to	to	PART
admet-505	491	10	indicate	indicate	VERB
admet-505	491	11	the	the	DET
admet-505	491	12	same	same	ADJ
admet-505	491	13	micellization	micellization	NOUN
admet-505	491	14	slopes	slope	NOUN
admet-505	491	15	.	.	PUNCT
admet-505	492	1	also	also	ADV
admet-505	492	2	,	,	PUNCT
admet-505	492	3	the	the	DET
admet-505	492	4	slopes	slope	NOUN
admet-505	492	5	at	at	ADP
admet-505	492	6	25	25	NUM
admet-505	492	7	and	and	CCONJ
admet-505	492	8	37	37	NUM
admet-505	492	9	°	°	NOUN
admet-505	492	10	c	c	NOUN
admet-505	492	11	appear	appear	VERB
admet-505	492	12	to	to	PART
admet-505	492	13	be	be	AUX
admet-505	492	14	nearly	nearly	ADV
admet-505	492	15	the	the	DET
admet-505	492	16	same	same	ADJ
admet-505	492	17	for	for	ADP
admet-505	492	18	the	the	DET
admet-505	492	19	drug	drug	NOUN
admet-505	492	20	.	.	PUNCT
admet-505	493	1	alex	alex	PROPN
admet-505	493	2	avdeef	avdeef	PROPN
admet-505	493	3	admet	admet	PROPN
admet-505	493	4	&	&	CCONJ
admet-505	493	5	dmpk	dmpk	PROPN
admet-505	493	6	6(2	6(2	NUM
admet-505	493	7	)	)	PUNCT
admet-505	493	8	(	(	PUNCT
admet-505	493	9	2018	2018	NUM
admet-505	493	10	)	)	PUNCT
admet-505	493	11	105	105	NUM
admet-505	493	12	-	-	SYM
admet-505	493	13	139	139	NUM
admet-505	493	14	120	120	NUM
admet-505	493	15	figure	figure	NOUN
admet-505	493	16	3	3	NUM
admet-505	493	17	.	.	PUNCT
admet-505	494	1	examples	example	NOUN
admet-505	494	2	of	of	ADP
admet-505	494	3	micellization	micellization	NOUN
admet-505	494	4	plots	plot	NOUN
admet-505	494	5	of	of	ADP
admet-505	494	6	largely	largely	ADV
admet-505	494	7	nonionized	nonionize	VERB
admet-505	494	8	acidic	acidic	ADJ
admet-505	494	9	drugs	drug	NOUN
admet-505	494	10	.	.	PUNCT
admet-505	495	1	in	in	ADP
admet-505	495	2	the	the	DET
admet-505	495	3	first	first	ADJ
admet-505	495	4	seven	seven	NUM
admet-505	495	5	frames	frame	NOUN
admet-505	495	6	,	,	PUNCT
admet-505	495	7	the	the	DET
admet-505	495	8	medium	medium	NOUN
admet-505	495	9	was	be	AUX
admet-505	495	10	distilled	distil	VERB
admet-505	495	11	water	water	NOUN
admet-505	495	12	.	.	PUNCT
admet-505	496	1	in	in	ADP
admet-505	496	2	figure	figure	NOUN
admet-505	496	3	3h	3h	NUM
admet-505	496	4	,	,	PUNCT
admet-505	496	5	hcl	hcl	PROPN
admet-505	496	6	was	be	AUX
admet-505	496	7	added	add	VERB
admet-505	496	8	to	to	PART
admet-505	496	9	adjust	adjust	VERB
admet-505	496	10	the	the	DET
admet-505	496	11	solution	solution	NOUN
admet-505	496	12	to	to	ADP
admet-505	496	13	ph	ph	ADJ
admet-505	496	14	2	2	NUM
admet-505	496	15	(	(	PUNCT
admet-505	496	16	where	where	SCONJ
admet-505	496	17	salicylic	salicylic	ADJ
admet-505	496	18	acid	acid	NOUN
admet-505	496	19	is	be	AUX
admet-505	496	20	largely	largely	ADV
admet-505	496	21	uncharged	uncharged	ADJ
admet-505	496	22	)	)	PUNCT
admet-505	496	23	.	.	PUNCT
admet-505	497	1	in	in	ADP
admet-505	497	2	figure	figure	NOUN
admet-505	497	3	3i	3i	NOUN
admet-505	497	4	,	,	PUNCT
admet-505	497	5	3	3	NUM
admet-505	497	6	mm	mm	NOUN
admet-505	497	7	phosphate	phosphate	NOUN
admet-505	497	8	buffer	buffer	NOUN
admet-505	497	9	at	at	ADP
admet-505	497	10	ph	ph	PROPN
admet-505	497	11	7.4	7.4	NUM
admet-505	497	12	was	be	AUX
admet-505	497	13	used	use	VERB
admet-505	497	14	,	,	PUNCT
admet-505	497	15	although	although	SCONJ
admet-505	497	16	pdisol	pdisol	ADJ
admet-505	497	17	-	-	PUNCT
admet-505	497	18	x	x	NOUN
admet-505	497	19	calculation	calculation	NOUN
admet-505	497	20	suggests	suggest	VERB
admet-505	497	21	that	that	SCONJ
admet-505	497	22	in	in	ADP
admet-505	497	23	the	the	DET
admet-505	497	24	low	low	ADJ
admet-505	497	25	buffer	buffer	NOUN
admet-505	497	26	capacity	capacity	NOUN
admet-505	497	27	solution	solution	NOUN
admet-505	497	28	,	,	PUNCT
admet-505	497	29	the	the	DET
admet-505	497	30	ph	ph	NOUN
admet-505	497	31	may	may	AUX
admet-505	497	32	have	have	AUX
admet-505	497	33	been	be	AUX
admet-505	497	34	as	as	ADV
admet-505	497	35	low	low	ADJ
admet-505	497	36	as	as	ADP
admet-505	497	37	4.2	4.2	NUM
admet-505	497	38	(	(	PUNCT
admet-505	497	39	the	the	DET
admet-505	497	40	final	final	ADJ
admet-505	497	41	ph	ph	ADJ
admet-505	497	42	values	value	NOUN
admet-505	497	43	of	of	ADP
admet-505	497	44	the	the	DET
admet-505	497	45	valsartan	valsartan	PROPN
admet-505	497	46	solutions	solution	NOUN
admet-505	497	47	were	be	AUX
admet-505	497	48	not	not	PART
admet-505	497	49	reported	report	VERB
admet-505	497	50	)	)	PUNCT
admet-505	497	51	.	.	PUNCT
admet-505	498	1	in	in	ADP
admet-505	498	2	these	these	DET
admet-505	498	3	cases	case	NOUN
admet-505	498	4	,	,	PUNCT
admet-505	498	5	it	it	PRON
admet-505	498	6	was	be	AUX
admet-505	498	7	assumed	assume	VERB
admet-505	498	8	that	that	SCONJ
admet-505	498	9	ionization	ionization	NOUN
admet-505	498	10	of	of	ADP
admet-505	498	11	the	the	DET
admet-505	498	12	acids	acid	NOUN
admet-505	498	13	was	be	AUX
admet-505	498	14	insignificant	insignificant	ADJ
admet-505	498	15	.	.	PUNCT
admet-505	499	1	most	most	ADJ
admet-505	499	2	of	of	ADP
admet-505	499	3	the	the	DET
admet-505	499	4	cmc	cmc	NOUN
admet-505	499	5	values	value	NOUN
admet-505	499	6	are	be	AUX
admet-505	499	7	in	in	ADP
admet-505	499	8	the	the	DET
admet-505	499	9	interval	interval	NOUN
admet-505	499	10	2.4	2.4	NUM
admet-505	499	11	-	-	SYM
admet-505	499	12	8.2	8.2	NUM
admet-505	499	13	mm	mm	NOUN
admet-505	499	14	.	.	PUNCT
admet-505	500	1	the	the	DET
admet-505	500	2	micellar	micellar	ADJ
admet-505	500	3	-	-	PUNCT
admet-505	500	4	portion	portion	NOUN
admet-505	500	5	curves	curve	NOUN
admet-505	500	6	show	show	VERB
admet-505	500	7	slight	slight	ADJ
admet-505	500	8	curvature	curvature	NOUN
admet-505	500	9	for	for	ADP
admet-505	500	10	phenytoin	phenytoin	NOUN
admet-505	500	11	(	(	PUNCT
admet-505	500	12	g	g	NOUN
admet-505	500	13	)	)	PUNCT
admet-505	500	14	and	and	CCONJ
admet-505	500	15	salicylic	salicylic	ADJ
admet-505	500	16	acid	acid	NOUN
admet-505	500	17	(	(	PUNCT
admet-505	500	18	h	h	NOUN
admet-505	500	19	)	)	PUNCT
admet-505	500	20	,	,	PUNCT
admet-505	500	21	as	as	SCONJ
admet-505	500	22	the	the	DET
admet-505	500	23	surfactant	surfactant	ADJ
admet-505	500	24	concentrations	concentration	NOUN
admet-505	500	25	extend	extend	VERB
admet-505	500	26	to	to	ADP
admet-505	500	27	277	277	NUM
admet-505	500	28	and	and	CCONJ
admet-505	500	29	173	173	NUM
admet-505	500	30	mm	mm	NOUN
admet-505	500	31	,	,	PUNCT
admet-505	500	32	respectively	respectively	ADV
admet-505	500	33	.	.	PUNCT
admet-505	501	1	indomethacin	indomethacin	PROPN
admet-505	501	2	(	(	PUNCT
admet-505	501	3	f	f	X
admet-505	501	4	)	)	PUNCT
admet-505	501	5	also	also	ADV
admet-505	501	6	extends	extend	VERB
admet-505	501	7	to	to	ADP
admet-505	501	8	high	high	ADJ
admet-505	501	9	surfactant	surfactant	ADJ
admet-505	501	10	concentrations	concentration	NOUN
admet-505	501	11	(	(	PUNCT
admet-505	501	12	238	238	NUM
admet-505	501	13	mm	mm	NOUN
admet-505	501	14	)	)	PUNCT
admet-505	501	15	but	but	CCONJ
admet-505	501	16	does	do	AUX
admet-505	501	17	not	not	PART
admet-505	501	18	indicate	indicate	VERB
admet-505	501	19	nonlinearity	nonlinearity	NOUN
admet-505	501	20	.	.	PUNCT
admet-505	502	1	in	in	ADP
admet-505	502	2	the	the	DET
admet-505	502	3	plots	plot	NOUN
admet-505	502	4	of	of	ADP
admet-505	502	5	indomethacin	indomethacin	NOUN
admet-505	502	6	and	and	CCONJ
admet-505	502	7	valsartan	valsartan	PROPN
admet-505	502	8	,	,	PUNCT
admet-505	502	9	the	the	DET
admet-505	502	10	cmc	cmc	NOUN
admet-505	502	11	is	be	AUX
admet-505	502	12	very	very	ADV
admet-505	502	13	close	close	ADJ
admet-505	502	14	to	to	ADP
admet-505	502	15	zero	zero	NUM
admet-505	502	16	.	.	PUNCT
admet-505	503	1	the	the	DET
admet-505	503	2	data	datum	NOUN
admet-505	503	3	in	in	ADP
admet-505	503	4	the	the	DET
admet-505	503	5	case	case	NOUN
admet-505	503	6	of	of	ADP
admet-505	503	7	ibuprofen	ibuprofen	NOUN
admet-505	503	8	(	(	PUNCT
admet-505	503	9	e	e	NOUN
admet-505	503	10	)	)	PUNCT
admet-505	503	11	show	show	VERB
admet-505	503	12	peculiar	peculiar	ADJ
admet-505	503	13	variance	variance	NOUN
admet-505	503	14	,	,	PUNCT
admet-505	503	15	for	for	ADP
admet-505	503	16	[	[	X
admet-505	503	17	sds	sds	X
admet-505	503	18	]	]	X
admet-505	503	19	<	<	X
admet-505	503	20	7	7	NUM
admet-505	503	21	and	and	CCONJ
admet-505	503	22	>	>	X
admet-505	503	23	15	15	NUM
admet-505	503	24	mm	mm	NOUN
admet-505	503	25	.	.	PROPN
admet-505	503	26	four	four	NUM
admet-505	503	27	of	of	ADP
admet-505	503	28	the	the	DET
admet-505	503	29	low	low	ADJ
admet-505	503	30	-	-	PUNCT
admet-505	503	31	soluble	soluble	ADJ
admet-505	503	32	compounds	compound	NOUN
admet-505	503	33	bind	bind	VERB
admet-505	503	34	as	as	ADP
admet-505	503	35	2	2	NUM
admet-505	503	36	drugs	drug	NOUN
admet-505	503	37	per	per	ADP
admet-505	503	38	micelle	micelle	NOUN
admet-505	503	39	,	,	PUNCT
admet-505	503	40	with	with	ADP
admet-505	503	41	kn	kn	PROPN
admet-505	503	42	ranging	range	VERB
admet-505	503	43	from	from	ADP
admet-505	503	44	10	10	NUM
admet-505	503	45	+8.5	+8.5	NOUN
admet-505	503	46	(	(	PUNCT
admet-505	503	47	phenytoin	phenytoin	NOUN
admet-505	503	48	)	)	PUNCT
admet-505	503	49	to	to	ADP
admet-505	503	50	10	10	NUM
admet-505	503	51	+16	+16	ADJ
admet-505	503	52	(	(	PUNCT
admet-505	503	53	curcumin	curcumin	NOUN
admet-505	503	54	)	)	PUNCT
admet-505	503	55	.	.	PUNCT
admet-505	504	1	values	value	NOUN
admet-505	504	2	of	of	ADP
admet-505	504	3	n	n	PRON
admet-505	504	4	for	for	ADP
admet-505	504	5	the	the	DET
admet-505	504	6	more	more	ADV
admet-505	504	7	soluble	soluble	ADJ
admet-505	504	8	drugs	drug	NOUN
admet-505	504	9	range	range	VERB
admet-505	504	10	from	from	ADP
admet-505	504	11	20	20	NUM
admet-505	504	12	(	(	PUNCT
admet-505	504	13	valsartan	valsartan	PROPN
admet-505	504	14	)	)	PUNCT
admet-505	504	15	to	to	ADP
admet-505	504	16	40	40	NUM
admet-505	504	17	(	(	PUNCT
admet-505	504	18	butylparaben	butylparaben	NOUN
admet-505	504	19	)	)	PUNCT
admet-505	504	20	,	,	PUNCT
admet-505	504	21	with	with	ADP
admet-505	504	22	corresponding	correspond	VERB
admet-505	504	23	kn	kn	PROPN
admet-505	504	24	values	value	NOUN
admet-505	504	25	from	from	ADP
admet-505	504	26	10	10	NUM
admet-505	504	27	+75	+75	NOUN
admet-505	504	28	to	to	ADP
admet-505	504	29	10	10	NUM
admet-505	504	30	+118	+118	NUM
admet-505	504	31	m	m	NUM
admet-505	504	32	-n	-n	NOUN
admet-505	504	33	,	,	PUNCT
admet-505	504	34	respectively	respectively	ADV
admet-505	504	35	(	(	PUNCT
admet-505	504	36	cf	cf	NOUN
admet-505	504	37	.	.	NOUN
admet-505	504	38	,	,	PUNCT
admet-505	504	39	table	table	NOUN
admet-505	504	40	1	1	NUM
admet-505	504	41	)	)	PUNCT
admet-505	504	42	.	.	PUNCT
admet-505	505	1	admet	admet	PROPN
admet-505	505	2	&	&	CCONJ
admet-505	505	3	dmpk	dmpk	PROPN
admet-505	505	4	6(2	6(2	NUM
admet-505	505	5	)	)	PUNCT
admet-505	505	6	(	(	PUNCT
admet-505	505	7	2018	2018	NUM
admet-505	505	8	)	)	PUNCT
admet-505	505	9	105	105	NUM
admet-505	505	10	-	-	SYM
admet-505	505	11	139	139	NUM
admet-505	505	12	cocrystal	cocrystal	ADJ
admet-505	505	13	solubility	solubility	NOUN
admet-505	505	14	-	-	PUNCT
admet-505	505	15	ph	ph	VERB
admet-505	505	16	,	,	PUNCT
admet-505	505	17	drug	drug	NOUN
admet-505	505	18	solubilization	solubilization	NOUN
admet-505	505	19	capacity	capacity	NOUN
admet-505	505	20	of	of	ADP
admet-505	505	21	sds	sds	PROPN
admet-505	505	22	,	,	PUNCT
admet-505	505	23	mass	mass	ADJ
admet-505	505	24	action	action	NOUN
admet-505	505	25	model	model	NOUN
admet-505	505	26	doi	doi	PROPN
admet-505	505	27	:	:	PUNCT
admet-505	505	28	10.5599	10.5599	NUM
admet-505	505	29	/	/	SYM
admet-505	505	30	admet.505	admet.505	PROPN
admet-505	505	31	121	121	NUM
admet-505	505	32	figure	figure	NOUN
admet-505	505	33	4	4	NUM
admet-505	505	34	.	.	PUNCT
admet-505	505	35	examples	example	NOUN
admet-505	505	36	of	of	ADP
admet-505	505	37	micellization	micellization	NOUN
admet-505	505	38	plots	plot	NOUN
admet-505	505	39	of	of	ADP
admet-505	505	40	largely	largely	ADV
admet-505	505	41	nonionized	nonionize	VERB
admet-505	505	42	basic	basic	ADJ
admet-505	505	43	drugs	drug	NOUN
admet-505	505	44	.	.	PUNCT
admet-505	506	1	erythromycin	erythromycin	NOUN
admet-505	506	2	(	(	PUNCT
admet-505	506	3	b	b	NOUN
admet-505	506	4	)	)	PUNCT
admet-505	506	5	and	and	CCONJ
admet-505	506	6	nsc-639829	nsc-639829	NOUN
admet-505	506	7	(	(	PUNCT
admet-505	506	8	c	c	X
admet-505	506	9	)	)	PUNCT
admet-505	506	10	show	show	NOUN
admet-505	506	11	curvature	curvature	NOUN
admet-505	506	12	in	in	ADP
admet-505	506	13	the	the	DET
admet-505	506	14	micellar	micellar	ADJ
admet-505	506	15	portion	portion	NOUN
admet-505	506	16	of	of	ADP
admet-505	506	17	the	the	DET
admet-505	506	18	curves	curve	NOUN
admet-505	506	19	,	,	PUNCT
admet-505	506	20	even	even	ADV
admet-505	506	21	over	over	ADP
admet-505	506	22	relatively	relatively	ADV
admet-505	506	23	low	low	ADJ
admet-505	506	24	surfactant	surfactant	ADJ
admet-505	506	25	concentrations	concentration	NOUN
admet-505	506	26	.	.	PUNCT
admet-505	507	1	atazanavir	atazanavir	PROPN
admet-505	507	2	binds	bind	VERB
admet-505	507	3	1:1	1:1	NUM
admet-505	507	4	with	with	ADP
admet-505	507	5	micelles	micelle	NOUN
admet-505	507	6	,	,	PUNCT
admet-505	507	7	with	with	ADP
admet-505	507	8	k1	k1	NOUN
admet-505	507	9	=	=	SYM
admet-505	507	10	10	10	NUM
admet-505	507	11	+5.3	+5.3	NUM
admet-505	507	12	m	m	NOUN
admet-505	507	13	-1	-1	PRON
admet-505	508	1	(	(	PUNCT
admet-505	508	2	eq	eq	NOUN
admet-505	508	3	.	.	PROPN
admet-505	508	4	13	13	NUM
admet-505	508	5	)	)	PUNCT
admet-505	508	6	.	.	PUNCT
admet-505	509	1	the	the	DET
admet-505	509	2	most	most	ADV
admet-505	509	3	insoluble	insoluble	ADJ
admet-505	509	4	of	of	ADP
admet-505	509	5	the	the	DET
admet-505	509	6	bases	basis	NOUN
admet-505	509	7	,	,	PUNCT
admet-505	509	8	nsc-639829	nsc-639829	NOUN
admet-505	509	9	,	,	PUNCT
admet-505	509	10	binds	bind	VERB
admet-505	509	11	as	as	ADP
admet-505	509	12	4:1	4:1	NUM
admet-505	509	13	with	with	ADP
admet-505	509	14	micelles	micelle	NOUN
admet-505	509	15	,	,	PUNCT
admet-505	509	16	with	with	ADP
admet-505	509	17	k4	k4	PROPN
admet-505	509	18	=	=	PROPN
admet-505	509	19	10	10	NUM
admet-505	509	20	+30	+30	NUM
admet-505	509	21	m	m	NOUN
admet-505	509	22	-4	-4	INTJ
admet-505	509	23	.	.	PUNCT
admet-505	510	1	the	the	DET
admet-505	510	2	other	other	ADJ
admet-505	510	3	values	value	NOUN
admet-505	510	4	of	of	ADP
admet-505	510	5	n	n	NUM
admet-505	510	6	range	range	VERB
admet-505	510	7	from	from	ADP
admet-505	510	8	10	10	NUM
admet-505	510	9	to	to	PART
admet-505	510	10	26	26	NUM
admet-505	510	11	(	(	PUNCT
admet-505	510	12	cf	cf	NOUN
admet-505	510	13	.	.	PUNCT
admet-505	510	14	,	,	PUNCT
admet-505	510	15	table	table	NOUN
admet-505	510	16	1	1	NUM
admet-505	510	17	)	)	PUNCT
admet-505	510	18	.	.	PUNCT
admet-505	511	1	figure	figure	NOUN
admet-505	511	2	5	5	NUM
admet-505	511	3	.	.	PUNCT
admet-505	512	1	examples	example	NOUN
admet-505	512	2	of	of	ADP
admet-505	512	3	the	the	DET
admet-505	512	4	effect	effect	NOUN
admet-505	512	5	of	of	ADP
admet-505	512	6	salt	salt	NOUN
admet-505	512	7	on	on	ADP
admet-505	512	8	micellization	micellization	NOUN
admet-505	512	9	.	.	PUNCT
admet-505	513	1	with	with	ADP
admet-505	513	2	the	the	DET
admet-505	513	3	apparent	apparent	ADJ
admet-505	513	4	exception	exception	NOUN
admet-505	513	5	of	of	ADP
admet-505	513	6	buffered	buffer	VERB
admet-505	513	7	solutions	solution	NOUN
admet-505	513	8	of	of	ADP
admet-505	513	9	mefenamic	mefenamic	ADJ
admet-505	513	10	acid	acid	NOUN
admet-505	513	11	(	(	PUNCT
admet-505	513	12	s0	s0	NOUN
admet-505	513	13	=	=	SYM
admet-505	513	14	0.6	0.6	NUM
admet-505	513	15	μm	μm	NUM
admet-505	513	16	)	)	PUNCT
admet-505	513	17	and	and	CCONJ
admet-505	513	18	,	,	PUNCT
admet-505	513	19	to	to	ADP
admet-505	513	20	a	a	DET
admet-505	513	21	lesser	less	ADJ
admet-505	513	22	extent	extent	NOUN
admet-505	513	23	,	,	PUNCT
admet-505	513	24	of	of	ADP
admet-505	513	25	resveratrol	resveratrol	NOUN
admet-505	513	26	(	(	PUNCT
admet-505	513	27	s0	s0	NOUN
admet-505	513	28	=	=	PUNCT
admet-505	513	29	180	180	NUM
admet-505	513	30	μm	μm	NUM
admet-505	513	31	)	)	PUNCT
admet-505	513	32	,	,	PUNCT
admet-505	513	33	the	the	DET
admet-505	513	34	examples	example	NOUN
admet-505	513	35	comparing	compare	VERB
admet-505	513	36	water	water	NOUN
admet-505	513	37	to	to	ADP
admet-505	513	38	0.15	0.15	NUM
admet-505	513	39	m	m	NOUN
admet-505	513	40	nacl	nacl	ADJ
admet-505	513	41	solutions	solution	NOUN
admet-505	513	42	show	show	VERB
admet-505	513	43	that	that	SCONJ
admet-505	513	44	k	k	PROPN
admet-505	513	45	values	value	NOUN
admet-505	513	46	decrease	decrease	VERB
admet-505	513	47	with	with	ADP
admet-505	513	48	increasing	increase	VERB
admet-505	513	49	salt	salt	NOUN
admet-505	513	50	.	.	PUNCT
admet-505	514	1	also	also	ADV
admet-505	514	2	,	,	PUNCT
admet-505	514	3	the	the	DET
admet-505	514	4	cmc	cmc	NOUN
admet-505	514	5	decreases	decrease	VERB
admet-505	514	6	with	with	ADP
admet-505	514	7	increasing	increase	VERB
admet-505	514	8	salt	salt	NOUN
admet-505	514	9	concentration	concentration	NOUN
admet-505	514	10	,	,	PUNCT
admet-505	514	11	an	an	DET
admet-505	514	12	effect	effect	NOUN
admet-505	514	13	expected	expect	VERB
admet-505	514	14	from	from	ADP
admet-505	514	15	properties	property	NOUN
admet-505	514	16	of	of	ADP
admet-505	514	17	sds	sds	PROPN
admet-505	514	18	in	in	ADP
admet-505	514	19	the	the	DET
admet-505	514	20	absence	absence	NOUN
admet-505	514	21	of	of	ADP
admet-505	514	22	drug	drug	NOUN
admet-505	514	23	,	,	PUNCT
admet-505	514	24	as	as	SCONJ
admet-505	514	25	illustrated	illustrate	VERB
admet-505	514	26	in	in	ADP
admet-505	514	27	figure	figure	NOUN
admet-505	514	28	1	1	NUM
admet-505	514	29	.	.	PUNCT
admet-505	514	30	with	with	ADP
admet-505	514	31	lower	low	ADJ
admet-505	514	32	cmc	cmc	NOUN
admet-505	514	33	,	,	PUNCT
admet-505	514	34	the	the	DET
admet-505	514	35	micelle	micelle	NOUN
admet-505	514	36	structures	structure	NOUN
admet-505	514	37	become	become	VERB
admet-505	514	38	more	more	ADV
admet-505	514	39	stabilized	stabilize	VERB
admet-505	514	40	due	due	ADJ
admet-505	514	41	to	to	ADP
admet-505	514	42	reduced	reduce	VERB
admet-505	514	43	head	head	NOUN
admet-505	514	44	group	group	NOUN
admet-505	514	45	charge	charge	NOUN
admet-505	514	46	repulsions	repulsion	NOUN
admet-505	514	47	,	,	PUNCT
admet-505	514	48	which	which	PRON
admet-505	514	49	lead	lead	VERB
admet-505	514	50	to	to	ADP
admet-505	514	51	reduced	reduce	VERB
admet-505	514	52	drug	drug	NOUN
admet-505	514	53	solubilization	solubilization	NOUN
admet-505	514	54	.	.	PUNCT
admet-505	515	1	the	the	DET
admet-505	515	2	addition	addition	NOUN
admet-505	515	3	of	of	ADP
admet-505	515	4	buffer	buffer	NOUN
admet-505	515	5	,	,	PUNCT
admet-505	515	6	as	as	ADP
admet-505	515	7	in	in	ADP
admet-505	515	8	the	the	DET
admet-505	515	9	cases	case	NOUN
admet-505	515	10	of	of	ADP
admet-505	515	11	mefenamic	mefenamic	ADJ
admet-505	515	12	acid	acid	NOUN
admet-505	515	13	(	(	PUNCT
admet-505	515	14	b	b	NOUN
admet-505	515	15	)	)	PUNCT
admet-505	515	16	and	and	CCONJ
admet-505	515	17	resveratrol	resveratrol	NOUN
admet-505	515	18	(	(	PUNCT
admet-505	515	19	e	e	NOUN
admet-505	515	20	)	)	PUNCT
admet-505	515	21	contributes	contribute	VERB
admet-505	515	22	to	to	ADP
admet-505	515	23	the	the	DET
admet-505	515	24	ionization	ionization	NOUN
admet-505	515	25	of	of	ADP
admet-505	515	26	the	the	DET
admet-505	515	27	drugs	drug	NOUN
admet-505	515	28	,	,	PUNCT
admet-505	515	29	which	which	PRON
admet-505	515	30	impacts	impact	VERB
admet-505	515	31	on	on	ADP
admet-505	515	32	the	the	DET
admet-505	515	33	solubility	solubility	NOUN
admet-505	515	34	,	,	PUNCT
admet-505	515	35	but	but	CCONJ
admet-505	515	36	not	not	PART
admet-505	515	37	so	so	ADV
admet-505	515	38	much	much	ADV
admet-505	515	39	on	on	ADP
admet-505	515	40	the	the	DET
admet-505	515	41	solubilization	solubilization	NOUN
admet-505	515	42	capacity	capacity	NOUN
admet-505	515	43	.	.	PUNCT
admet-505	516	1	alex	alex	PROPN
admet-505	516	2	avdeef	avdeef	PROPN
admet-505	516	3	admet	admet	PROPN
admet-505	516	4	&	&	CCONJ
admet-505	516	5	dmpk	dmpk	PROPN
admet-505	516	6	6(2	6(2	NUM
admet-505	516	7	)	)	PUNCT
admet-505	516	8	(	(	PUNCT
admet-505	516	9	2018	2018	NUM
admet-505	516	10	)	)	PUNCT
admet-505	516	11	105	105	NUM
admet-505	516	12	-	-	SYM
admet-505	516	13	139	139	NUM
admet-505	516	14	122	122	NUM
admet-505	516	15	figure	figure	NOUN
admet-505	516	16	6	6	NUM
admet-505	516	17	.	.	NOUN
admet-505	516	18	example	example	NOUN
admet-505	516	19	of	of	ADP
admet-505	516	20	the	the	DET
admet-505	516	21	effect	effect	NOUN
admet-505	516	22	of	of	ADP
admet-505	516	23	temperature	temperature	NOUN
admet-505	516	24	on	on	ADP
admet-505	516	25	micellization	micellization	NOUN
admet-505	516	26	.	.	PUNCT
admet-505	517	1	ibuprofen	ibuprofen	PROPN
admet-505	517	2	shows	show	VERB
admet-505	517	3	higher	high	ADJ
admet-505	517	4	degree	degree	NOUN
admet-505	517	5	of	of	ADP
admet-505	517	6	solubilization	solubilization	NOUN
admet-505	517	7	at	at	ADP
admet-505	517	8	37	37	NUM
admet-505	517	9	°	°	NOUN
admet-505	517	10	c	c	NOUN
admet-505	517	11	(	(	PUNCT
admet-505	517	12	26	26	NUM
admet-505	517	13	drugs	drug	NOUN
admet-505	517	14	/	/	SYM
admet-505	517	15	micelle	micelle	NOUN
admet-505	517	16	,	,	PUNCT
admet-505	517	17	table	table	NOUN
admet-505	517	18	1	1	NUM
admet-505	517	19	)	)	PUNCT
admet-505	517	20	,	,	PUNCT
admet-505	517	21	compared	compare	VERB
admet-505	517	22	to	to	ADP
admet-505	517	23	27	27	NUM
admet-505	517	24	°	°	NOUN
admet-505	517	25	c	c	X
admet-505	517	26	(	(	PUNCT
admet-505	517	27	16	16	NUM
admet-505	517	28	drugs	drug	NOUN
admet-505	517	29	/	/	SYM
admet-505	517	30	micelle	micelle	NOUN
admet-505	517	31	)	)	PUNCT
admet-505	517	32	.	.	PUNCT
admet-505	518	1	the	the	DET
admet-505	518	2	cmc	cmc	NOUN
admet-505	518	3	is	be	AUX
admet-505	518	4	only	only	ADV
admet-505	518	5	slightly	slightly	ADV
admet-505	518	6	elevated	elevate	VERB
admet-505	518	7	at	at	ADP
admet-505	518	8	the	the	DET
admet-505	518	9	higher	high	ADJ
admet-505	518	10	temperature	temperature	NOUN
admet-505	518	11	.	.	PUNCT
admet-505	519	1	the	the	DET
admet-505	519	2	formation	formation	NOUN
admet-505	519	3	of	of	ADP
admet-505	519	4	micelles	micelle	NOUN
admet-505	519	5	is	be	AUX
admet-505	519	6	entropy	entropy	NOUN
admet-505	519	7	driven	drive	VERB
admet-505	519	8	,	,	PUNCT
admet-505	519	9	due	due	ADP
admet-505	519	10	to	to	ADP
admet-505	519	11	the	the	DET
admet-505	519	12	release	release	NOUN
admet-505	519	13	of	of	ADP
admet-505	519	14	water	water	NOUN
admet-505	519	15	structure	structure	NOUN
admet-505	519	16	surrounding	surround	VERB
admet-505	519	17	hydrophobic	hydrophobic	NOUN
admet-505	519	18	groups	group	NOUN
admet-505	519	19	,	,	PUNCT
admet-505	519	20	as	as	SCONJ
admet-505	519	21	these	these	DET
admet-505	519	22	groups	group	NOUN
admet-505	519	23	migrate	migrate	VERB
admet-505	519	24	into	into	ADP
admet-505	519	25	the	the	DET
admet-505	519	26	micelle	micelle	NOUN
admet-505	519	27	core	core	NOUN
admet-505	520	1	[	[	X
admet-505	520	2	12	12	NUM
admet-505	520	3	]	]	PUNCT
admet-505	520	4	.	.	PUNCT
admet-505	521	1	above	above	ADP
admet-505	521	2	60	60	NUM
admet-505	521	3	°	°	NOUN
admet-505	521	4	c	c	NOUN
admet-505	521	5	,	,	PUNCT
admet-505	521	6	water	water	NOUN
admet-505	521	7	loses	lose	VERB
admet-505	521	8	most	most	ADJ
admet-505	521	9	of	of	ADP
admet-505	521	10	its	its	PRON
admet-505	521	11	ability	ability	NOUN
admet-505	521	12	to	to	PART
admet-505	521	13	form	form	VERB
admet-505	521	14	cavities	cavity	NOUN
admet-505	521	15	around	around	ADP
admet-505	521	16	hydrophobic	hydrophobic	NOUN
admet-505	521	17	groups	group	NOUN
admet-505	521	18	,	,	PUNCT
admet-505	521	19	so	so	SCONJ
admet-505	521	20	the	the	DET
admet-505	521	21	drive	drive	NOUN
admet-505	521	22	to	to	PART
admet-505	521	23	form	form	NOUN
admet-505	521	24	micelles	micelle	NOUN
admet-505	521	25	is	be	AUX
admet-505	521	26	weakened	weaken	VERB
admet-505	521	27	at	at	ADP
admet-505	521	28	elevated	elevated	ADJ
admet-505	521	29	temperature	temperature	NOUN
admet-505	521	30	,	,	PUNCT
admet-505	521	31	indicated	indicate	VERB
admet-505	521	32	by	by	ADP
admet-505	521	33	increased	increase	VERB
admet-505	521	34	cmc	cmc	NOUN
admet-505	521	35	[	[	X
admet-505	521	36	11	11	NUM
admet-505	521	37	,	,	PUNCT
admet-505	521	38	12	12	NUM
admet-505	521	39	]	]	PUNCT
admet-505	521	40	.	.	PUNCT
admet-505	522	1	urea	urea	PROPN
admet-505	522	2	also	also	ADV
admet-505	522	3	plays	play	VERB
admet-505	522	4	a	a	DET
admet-505	522	5	role	role	NOUN
admet-505	522	6	in	in	ADP
admet-505	522	7	“	"	PUNCT
admet-505	522	8	water	water	NOUN
admet-505	522	9	structure	structure	NOUN
admet-505	522	10	breaking	breaking	NOUN
admet-505	522	11	.	.	PUNCT
admet-505	522	12	”	"	PUNCT
admet-505	522	13	figure	figure	VERB
admet-505	522	14	7	7	NUM
admet-505	522	15	.	.	PUNCT
admet-505	522	16	examples	example	NOUN
admet-505	522	17	of	of	ADP
admet-505	522	18	effect	effect	NOUN
admet-505	522	19	of	of	ADP
admet-505	522	20	ph	ph	NOUN
admet-505	522	21	on	on	ADP
admet-505	522	22	micellization	micellization	NOUN
admet-505	522	23	.	.	PUNCT
admet-505	523	1	when	when	SCONJ
admet-505	523	2	ph	ph	NOUN
admet-505	523	3	of	of	ADP
admet-505	523	4	the	the	DET
admet-505	523	5	medium	medium	NOUN
admet-505	523	6	is	be	AUX
admet-505	523	7	adjusted	adjust	VERB
admet-505	523	8	with	with	ADP
admet-505	523	9	buffers	buffer	NOUN
admet-505	523	10	,	,	PUNCT
admet-505	523	11	the	the	DET
admet-505	523	12	calculated	calculated	ADJ
admet-505	523	13	water	water	NOUN
admet-505	523	14	solubility	solubility	NOUN
admet-505	523	15	needs	need	VERB
admet-505	523	16	to	to	PART
admet-505	523	17	take	take	VERB
admet-505	523	18	into	into	ADP
admet-505	523	19	account	account	NOUN
admet-505	523	20	the	the	DET
admet-505	523	21	pka	pka	NOUN
admet-505	523	22	of	of	ADP
admet-505	523	23	the	the	DET
admet-505	523	24	molecule	molecule	NOUN
admet-505	523	25	.	.	PUNCT
admet-505	524	1	sub	sub	ADJ
admet-505	524	2	-	-	ADJ
admet-505	524	3	cmc	cmc	ADJ
admet-505	524	4	data	datum	NOUN
admet-505	524	5	for	for	ADP
admet-505	524	6	carvedilol	carvedilol	NOUN
admet-505	524	7	(	(	PUNCT
admet-505	524	8	b	b	NOUN
admet-505	524	9	)	)	PUNCT
admet-505	524	10	and	and	CCONJ
admet-505	524	11	pg-300995	pg-300995	PROPN
admet-505	524	12	(	(	PUNCT
admet-505	524	13	e	e	NOUN
admet-505	524	14	)	)	PUNCT
admet-505	524	15	are	be	AUX
admet-505	524	16	not	not	PART
admet-505	524	17	shown	show	VERB
admet-505	524	18	,	,	PUNCT
admet-505	524	19	as	as	SCONJ
admet-505	524	20	these	these	PRON
admet-505	524	21	involve	involve	VERB
admet-505	524	22	the	the	DET
admet-505	524	23	precipitation	precipitation	NOUN
admet-505	524	24	of	of	ADP
admet-505	524	25	the	the	DET
admet-505	524	26	cationic	cationic	ADJ
admet-505	524	27	drugs	drug	NOUN
admet-505	524	28	and	and	CCONJ
admet-505	524	29	the	the	DET
admet-505	524	30	anionic	anionic	ADJ
admet-505	524	31	surfactant	surfactant	NOUN
admet-505	524	32	.	.	PUNCT
admet-505	525	1	with	with	ADP
admet-505	525	2	the	the	DET
admet-505	525	3	added	add	VERB
admet-505	525	4	complexity	complexity	NOUN
admet-505	525	5	,	,	PUNCT
admet-505	525	6	these	these	DET
admet-505	525	7	molecules	molecule	NOUN
admet-505	525	8	are	be	AUX
admet-505	525	9	further	far	ADV
admet-505	525	10	discussed	discuss	VERB
admet-505	525	11	in	in	ADP
admet-505	525	12	a	a	DET
admet-505	525	13	separate	separate	ADJ
admet-505	525	14	section	section	NOUN
admet-505	525	15	below	below	ADV
admet-505	525	16	.	.	PUNCT
admet-505	526	1	with	with	ADP
admet-505	526	2	the	the	DET
admet-505	526	3	exception	exception	NOUN
admet-505	526	4	of	of	ADP
admet-505	526	5	pg-300995	pg-300995	NOUN
admet-505	526	6	(	(	PUNCT
admet-505	526	7	e	e	NOUN
admet-505	526	8	)	)	PUNCT
admet-505	526	9	,	,	PUNCT
admet-505	526	10	the	the	DET
admet-505	526	11	k	k	PROPN
admet-505	526	12	values	value	NOUN
admet-505	526	13	do	do	AUX
admet-505	526	14	not	not	PART
admet-505	526	15	show	show	VERB
admet-505	526	16	appreciable	appreciable	ADJ
admet-505	526	17	dependence	dependence	NOUN
admet-505	526	18	on	on	ADP
admet-505	526	19	ph	ph	VERB
admet-505	526	20	,	,	PUNCT
admet-505	526	21	as	as	SCONJ
admet-505	526	22	indicated	indicate	VERB
admet-505	526	23	in	in	ADP
admet-505	526	24	frames	frame	NOUN
admet-505	526	25	(	(	PUNCT
admet-505	526	26	b	b	NOUN
admet-505	526	27	)	)	PUNCT
admet-505	526	28	,	,	PUNCT
admet-505	526	29	(	(	PUNCT
admet-505	526	30	d	d	NOUN
admet-505	526	31	)	)	PUNCT
admet-505	526	32	,	,	PUNCT
admet-505	526	33	and	and	CCONJ
admet-505	526	34	(	(	PUNCT
admet-505	526	35	f	f	X
admet-505	526	36	)	)	PUNCT
admet-505	526	37	.	.	PUNCT
admet-505	527	1	the	the	DET
admet-505	527	2	mass	mass	PROPN
admet-505	527	3	action	action	NOUN
admet-505	527	4	equilibrium	equilibrium	NOUN
admet-505	527	5	model	model	NOUN
admet-505	527	6	can	can	AUX
admet-505	527	7	rationalize	rationalize	VERB
admet-505	527	8	the	the	DET
admet-505	527	9	k	k	PROPN
admet-505	527	10	-ph	-ph	INTJ
admet-505	527	11	dependence	dependence	NOUN
admet-505	527	12	of	of	ADP
admet-505	527	13	pg-300995	pg-300995	NOUN
admet-505	527	14	(	(	PUNCT
admet-505	527	15	below	below	ADV
admet-505	527	16	)	)	PUNCT
admet-505	527	17	.	.	PUNCT
admet-505	528	1	admet	admet	PROPN
admet-505	528	2	&	&	CCONJ
admet-505	528	3	dmpk	dmpk	PROPN
admet-505	528	4	6(2	6(2	NUM
admet-505	528	5	)	)	PUNCT
admet-505	528	6	(	(	PUNCT
admet-505	528	7	2018	2018	NUM
admet-505	528	8	)	)	PUNCT
admet-505	528	9	105	105	NUM
admet-505	528	10	-	-	SYM
admet-505	528	11	139	139	NUM
admet-505	528	12	cocrystal	cocrystal	ADJ
admet-505	528	13	solubility	solubility	NOUN
admet-505	528	14	-	-	PUNCT
admet-505	528	15	ph	ph	VERB
admet-505	528	16	,	,	PUNCT
admet-505	528	17	drug	drug	NOUN
admet-505	528	18	solubilization	solubilization	NOUN
admet-505	528	19	capacity	capacity	NOUN
admet-505	528	20	of	of	ADP
admet-505	528	21	sds	sds	PROPN
admet-505	528	22	,	,	PUNCT
admet-505	528	23	mass	mass	ADJ
admet-505	528	24	action	action	NOUN
admet-505	528	25	model	model	NOUN
admet-505	528	26	doi	doi	PROPN
admet-505	528	27	:	:	PUNCT
admet-505	528	28	10.5599	10.5599	NUM
admet-505	528	29	/	/	SYM
admet-505	528	30	admet.505	admet.505	PROPN
admet-505	528	31	123	123	NUM
admet-505	528	32	a	a	DET
admet-505	528	33	significantly	significantly	ADV
admet-505	528	34	improved	improve	VERB
admet-505	528	35	correlation	correlation	NOUN
admet-505	528	36	(	(	PUNCT
admet-505	528	37	r	r	NOUN
admet-505	528	38	2	2	NUM
admet-505	528	39	=	=	SYM
admet-505	528	40	0.69	0.69	NUM
admet-505	528	41	)	)	PUNCT
admet-505	528	42	is	be	AUX
admet-505	528	43	evident	evident	ADJ
admet-505	528	44	between	between	ADP
admet-505	528	45	measured	measure	VERB
admet-505	528	46	log	log	NOUN
admet-505	528	47	k	k	PROPN
admet-505	528	48	and	and	CCONJ
admet-505	528	49	log	log	PROPN
admet-505	528	50	s0	s0	PROPN
admet-505	528	51	,	,	PUNCT
admet-505	528	52	as	as	SCONJ
admet-505	528	53	shown	show	VERB
admet-505	528	54	in	in	ADP
admet-505	528	55	figure	figure	NOUN
admet-505	528	56	8c	8c	NOUN
admet-505	528	57	.	.	PUNCT
admet-505	529	1	this	this	PRON
admet-505	529	2	might	might	AUX
admet-505	529	3	have	have	AUX
admet-505	529	4	been	be	AUX
admet-505	529	5	anticipated	anticipate	VERB
admet-505	529	6	by	by	ADP
admet-505	529	7	eq	eq	PROPN
admet-505	529	8	.	.	PUNCT
admet-505	530	1	(	(	PUNCT
admet-505	530	2	13	13	NUM
admet-505	530	3	)	)	PUNCT
admet-505	530	4	.	.	PUNCT
admet-505	531	1	the	the	DET
admet-505	531	2	standard	standard	ADJ
admet-505	531	3	deviation	deviation	NOUN
admet-505	531	4	,	,	PUNCT
admet-505	531	5	sd	sd	ADP
admet-505	531	6	=	=	SYM
admet-505	531	7	0.50	0.50	NUM
admet-505	531	8	log	log	NOUN
admet-505	531	9	unit	unit	NOUN
admet-505	531	10	,	,	PUNCT
admet-505	531	11	is	be	AUX
admet-505	531	12	suggestive	suggestive	ADJ
admet-505	531	13	of	of	ADP
admet-505	531	14	the	the	DET
admet-505	531	15	0.6	0.6	NUM
admet-505	531	16	-	-	SYM
admet-505	531	17	0.7	0.7	NUM
admet-505	531	18	log	log	NOUN
admet-505	531	19	unit	unit	NOUN
admet-505	531	20	often	often	ADV
admet-505	531	21	cited	cite	VERB
admet-505	531	22	interlaboratory	interlaboratory	ADJ
admet-505	531	23	reproducibility	reproducibility	NOUN
admet-505	531	24	in	in	ADP
admet-505	531	25	drug	drug	NOUN
admet-505	531	26	solubility	solubility	NOUN
admet-505	531	27	measurement	measurement	NOUN
admet-505	531	28	,	,	PUNCT
admet-505	531	29	although	although	SCONJ
admet-505	531	30	reproducibility	reproducibility	NOUN
admet-505	531	31	could	could	AUX
admet-505	531	32	be	be	AUX
admet-505	531	33	improved	improve	VERB
admet-505	531	34	if	if	SCONJ
admet-505	531	35	the	the	DET
admet-505	531	36	solubility	solubility	NOUN
admet-505	531	37	data	datum	NOUN
admet-505	531	38	were	be	AUX
admet-505	531	39	critically	critically	ADV
admet-505	531	40	processed	process	VERB
admet-505	531	41	[	[	PUNCT
admet-505	531	42	55	55	NUM
admet-505	531	43	]	]	PUNCT
admet-505	531	44	.	.	PUNCT
admet-505	532	1	an	an	DET
admet-505	532	2	examination	examination	NOUN
admet-505	532	3	of	of	ADP
admet-505	532	4	figure	figure	NOUN
admet-505	532	5	8c	8c	PROPN
admet-505	532	6	suggests	suggest	VERB
admet-505	532	7	that	that	SCONJ
admet-505	532	8	acids	acid	NOUN
admet-505	532	9	(	(	PUNCT
admet-505	532	10	red	red	ADJ
admet-505	532	11	circles	circle	NOUN
admet-505	532	12	)	)	PUNCT
admet-505	532	13	tend	tend	VERB
admet-505	532	14	to	to	PART
admet-505	532	15	distribute	distribute	VERB
admet-505	532	16	below	below	ADP
admet-505	532	17	the	the	DET
admet-505	532	18	correlation	correlation	NOUN
admet-505	532	19	line	line	NOUN
admet-505	532	20	for	for	ADP
admet-505	532	21	s0	s0	PROPN
admet-505	532	22	>	>	X
admet-505	532	23	1	1	NUM
admet-505	532	24	μm	μm	NOUN
admet-505	532	25	,	,	PUNCT
admet-505	532	26	suggesting	suggest	VERB
admet-505	532	27	that	that	SCONJ
admet-505	532	28	acid	acid	NOUN
admet-505	532	29	-	-	PUNCT
admet-505	532	30	base	base	NOUN
admet-505	532	31	properties	property	NOUN
admet-505	532	32	might	might	AUX
admet-505	532	33	correlate	correlate	VERB
admet-505	532	34	with	with	ADP
admet-505	532	35	k	k	PROPN
admet-505	532	36	values	value	NOUN
admet-505	532	37	.	.	PUNCT
admet-505	533	1	to	to	PART
admet-505	533	2	test	test	VERB
admet-505	533	3	the	the	DET
admet-505	533	4	k	k	PROPN
admet-505	533	5	data	datum	NOUN
admet-505	533	6	for	for	ADP
admet-505	533	7	further	further	ADJ
admet-505	533	8	relationships	relationship	NOUN
admet-505	533	9	,	,	PUNCT
admet-505	533	10	the	the	DET
admet-505	533	11	101	101	NUM
admet-505	533	12	-	-	PUNCT
admet-505	533	13	molecule	molecule	NOUN
admet-505	533	14	set	set	NOUN
admet-505	533	15	was	be	AUX
admet-505	533	16	subdivided	subdivide	VERB
admet-505	533	17	into	into	ADP
admet-505	533	18	four	four	NUM
admet-505	533	19	groups	group	NOUN
admet-505	533	20	,	,	PUNCT
admet-505	533	21	differentiated	differentiate	VERB
admet-505	533	22	by	by	ADP
admet-505	533	23	acid	acid	NOUN
admet-505	533	24	-	-	PUNCT
admet-505	533	25	base	base	NOUN
admet-505	533	26	indicator	indicator	NOUN
admet-505	533	27	indices	indice	VERB
admet-505	533	28	(	(	PUNCT
admet-505	533	29	0/1	0/1	NUM
admet-505	533	30	)	)	PUNCT
admet-505	533	31	,	,	PUNCT
admet-505	533	32	ia	ia	PROPN
admet-505	533	33	,	,	PUNCT
admet-505	533	34	ib	ib	PROPN
admet-505	533	35	,	,	PUNCT
admet-505	533	36	iab	iab	PROPN
admet-505	533	37	,	,	PUNCT
admet-505	533	38	in	in	ADV
admet-505	533	39	,	,	PUNCT
admet-505	533	40	to	to	PART
admet-505	533	41	designate	designate	VERB
admet-505	533	42	each	each	DET
admet-505	533	43	drug	drug	NOUN
admet-505	533	44	as	as	ADP
admet-505	533	45	an	an	DET
admet-505	533	46	acid	acid	NOUN
admet-505	533	47	,	,	PUNCT
admet-505	533	48	base	base	NOUN
admet-505	533	49	,	,	PUNCT
admet-505	533	50	ampholyte	ampholyte	ADJ
admet-505	533	51	,	,	PUNCT
admet-505	533	52	or	or	CCONJ
admet-505	533	53	neutral	neutral	ADJ
admet-505	533	54	type	type	NOUN
admet-505	533	55	,	,	PUNCT
admet-505	533	56	respectively	respectively	ADV
admet-505	533	57	(	(	PUNCT
admet-505	533	58	table	table	NOUN
admet-505	533	59	1	1	NUM
admet-505	533	60	)	)	PUNCT
admet-505	533	61	.	.	PUNCT
admet-505	534	1	each	each	DET
admet-505	534	2	k	k	PROPN
admet-505	534	3	sub	sub	NOUN
admet-505	534	4	-	-	NOUN
admet-505	534	5	group	group	NOUN
admet-505	534	6	of	of	ADP
admet-505	534	7	drugs	drug	NOUN
admet-505	534	8	was	be	AUX
admet-505	534	9	tested	test	VERB
admet-505	534	10	separately	separately	ADV
admet-505	534	11	,	,	PUNCT
admet-505	534	12	using	use	VERB
admet-505	534	13	log	log	NOUN
admet-505	534	14	s0	s0	PROPN
admet-505	534	15	,	,	PUNCT
admet-505	534	16	and	and	CCONJ
admet-505	534	17	just	just	ADV
admet-505	534	18	one	one	NUM
admet-505	534	19	of	of	ADP
admet-505	534	20	each	each	PRON
admet-505	534	21	of	of	ADP
admet-505	534	22	the	the	DET
admet-505	534	23	five	five	NUM
admet-505	534	24	abraham	abraham	PROPN
admet-505	534	25	[	[	X
admet-505	534	26	59	59	NUM
admet-505	534	27	]	]	PUNCT
admet-505	534	28	solvation	solvation	NOUN
admet-505	534	29	descriptors	descriptor	NOUN
admet-505	534	30	(	(	PUNCT
admet-505	534	31	σα2	σα2	NOUN
admet-505	534	32	h	h	NOUN
admet-505	534	33	,	,	PUNCT
admet-505	534	34	σβ2	σβ2	VERB
admet-505	534	35	h	h	NOUN
admet-505	534	36	:	:	PUNCT
admet-505	534	37	h	h	ADJ
admet-505	534	38	-	-	PUNCT
admet-505	534	39	bond	bond	NOUN
admet-505	534	40	acidity	acidity	NOUN
admet-505	534	41	and	and	CCONJ
admet-505	534	42	basicity	basicity	NOUN
admet-505	534	43	;	;	PUNCT
admet-505	534	44	π2	π2	ADV
admet-505	534	45	:	:	PUNCT
admet-505	534	46	dipolarity	dipolarity	NOUN
admet-505	534	47	/	/	SYM
admet-505	534	48	polarizability	polarizability	NOUN
admet-505	534	49	;	;	PUNCT
admet-505	534	50	r2	r2	NOUN
admet-505	534	51	:	:	PUNCT
admet-505	534	52	dispersion	dispersion	NOUN
admet-505	534	53	force	force	NOUN
admet-505	534	54	;	;	PUNCT
admet-505	534	55	and	and	CCONJ
admet-505	534	56	vx	vx	ADP
admet-505	534	57	:	:	PUNCT
admet-505	534	58	molar	molar	ADJ
admet-505	534	59	volume	volume	NOUN
admet-505	534	60	–	–	PUNCT
admet-505	534	61	see	see	VERB
admet-505	534	62	glossary	glossary	NOUN
admet-505	534	63	for	for	ADP
admet-505	534	64	further	further	ADJ
admet-505	534	65	elaboration	elaboration	NOUN
admet-505	534	66	;	;	PUNCT
admet-505	534	67	table	table	NOUN
admet-505	534	68	1	1	NUM
admet-505	534	69	lists	list	VERB
admet-505	534	70	the	the	DET
admet-505	534	71	five	five	NUM
admet-505	534	72	descriptors	descriptor	NOUN
admet-505	534	73	)	)	PUNCT
admet-505	534	74	.	.	PUNCT
admet-505	535	1	the	the	DET
admet-505	535	2	five	five	NUM
admet-505	535	3	descriptors	descriptor	NOUN
admet-505	535	4	were	be	AUX
admet-505	535	5	estimated	estimate	VERB
admet-505	535	6	from	from	ADP
admet-505	535	7	the	the	DET
admet-505	535	8	2d	2d	NUM
admet-505	535	9	structure	structure	NOUN
admet-505	535	10	of	of	ADP
admet-505	535	11	molecules	molecule	NOUN
admet-505	535	12	.	.	PUNCT
admet-505	536	1	table	table	NOUN
admet-505	536	2	2	2	NUM
admet-505	536	3	lists	list	VERB
admet-505	536	4	the	the	DET
admet-505	536	5	results	result	NOUN
admet-505	536	6	of	of	ADP
admet-505	536	7	the	the	DET
admet-505	536	8	best	well	ADV
admet-505	536	9	-	-	PUNCT
admet-505	536	10	fitting	fit	VERB
admet-505	536	11	combination	combination	NOUN
admet-505	536	12	of	of	ADP
admet-505	536	13	descriptors	descriptor	NOUN
admet-505	536	14	(	(	PUNCT
admet-505	536	15	no	no	DET
admet-505	536	16	more	more	ADJ
admet-505	536	17	than	than	ADP
admet-505	536	18	two	two	NUM
admet-505	536	19	per	per	ADP
admet-505	536	20	acidbase	acidbase	ADJ
admet-505	536	21	sub	sub	NOUN
admet-505	536	22	-	-	NOUN
admet-505	536	23	group	group	NOUN
admet-505	536	24	)	)	PUNCT
admet-505	536	25	.	.	PUNCT
admet-505	537	1	inclusion	inclusion	NOUN
admet-505	537	2	of	of	ADP
admet-505	537	3	abraham	abraham	PROPN
admet-505	537	4	h	h	PROPN
admet-505	537	5	-	-	PUNCT
admet-505	537	6	bond	bond	NOUN
admet-505	537	7	descriptors	descriptor	NOUN
admet-505	537	8	only	only	ADV
admet-505	537	9	slightly	slightly	ADV
admet-505	537	10	improved	improve	VERB
admet-505	537	11	the	the	DET
admet-505	537	12	fitting	fitting	ADJ
admet-505	537	13	(	(	PUNCT
admet-505	537	14	r	r	NOUN
admet-505	537	15	2	2	NUM
admet-505	537	16	increased	increase	VERB
admet-505	537	17	from	from	ADP
admet-505	537	18	0.69	0.69	NUM
admet-505	537	19	to	to	ADP
admet-505	537	20	0.74	0.74	NUM
admet-505	537	21	)	)	PUNCT
admet-505	537	22	.	.	PUNCT
admet-505	538	1	generally	generally	ADV
admet-505	538	2	,	,	PUNCT
admet-505	538	3	the	the	DET
admet-505	538	4	distribution	distribution	NOUN
admet-505	538	5	of	of	ADP
admet-505	538	6	solute	solute	NOUN
admet-505	538	7	between	between	ADP
admet-505	538	8	the	the	DET
admet-505	538	9	water	water	NOUN
admet-505	538	10	,	,	PUNCT
admet-505	538	11	solid	solid	ADJ
admet-505	538	12	,	,	PUNCT
admet-505	538	13	and	and	CCONJ
admet-505	538	14	micelles	micelle	NOUN
admet-505	538	15	is	be	AUX
admet-505	538	16	tilted	tilt	VERB
admet-505	538	17	towards	towards	ADP
admet-505	538	18	the	the	DET
admet-505	538	19	solid	solid	ADJ
admet-505	538	20	state	state	NOUN
admet-505	538	21	for	for	ADP
admet-505	538	22	highly	highly	ADV
admet-505	538	23	insoluble	insoluble	ADJ
admet-505	538	24	drugs	drug	NOUN
admet-505	538	25	,	,	PUNCT
admet-505	538	26	as	as	SCONJ
admet-505	538	27	evidenced	evidence	VERB
admet-505	538	28	by	by	ADP
admet-505	538	29	decreased	decrease	VERB
admet-505	538	30	solubilization	solubilization	NOUN
admet-505	538	31	capacity	capacity	NOUN
admet-505	538	32	.	.	PUNCT
admet-505	539	1	in	in	ADP
admet-505	539	2	the	the	DET
admet-505	539	3	case	case	NOUN
admet-505	539	4	of	of	ADP
admet-505	539	5	acids	acid	NOUN
admet-505	539	6	,	,	PUNCT
admet-505	539	7	strong	strong	ADJ
admet-505	539	8	h	h	NOUN
admet-505	539	9	-	-	PUNCT
admet-505	539	10	bond	bond	NOUN
admet-505	539	11	donor	donor	NOUN
admet-505	539	12	character	character	NOUN
admet-505	539	13	leads	lead	VERB
admet-505	539	14	to	to	PART
admet-505	539	15	decreased	decrease	VERB
admet-505	539	16	solubilization	solubilization	NOUN
admet-505	539	17	capacity	capacity	NOUN
admet-505	539	18	;	;	PUNCT
admet-505	539	19	for	for	ADP
admet-505	539	20	non	non	ADJ
admet-505	539	21	-	-	ADJ
admet-505	539	22	ionizable	ionizable	ADJ
admet-505	539	23	drugs	drug	NOUN
admet-505	539	24	and	and	CCONJ
admet-505	539	25	for	for	ADP
admet-505	539	26	ampholytes	ampholyte	NOUN
admet-505	539	27	,	,	PUNCT
admet-505	539	28	strong	strong	ADJ
admet-505	539	29	h	h	NOUN
admet-505	539	30	-	-	PUNCT
admet-505	539	31	bond	bond	NOUN
admet-505	539	32	acceptor	acceptor	NOUN
admet-505	539	33	character	character	NOUN
admet-505	539	34	leads	lead	VERB
admet-505	539	35	to	to	PART
admet-505	539	36	decreased	decrease	VERB
admet-505	539	37	solubilization	solubilization	NOUN
admet-505	539	38	by	by	ADP
admet-505	539	39	sds	sds	PROPN
admet-505	539	40	.	.	PUNCT
admet-505	540	1	in	in	ADP
admet-505	540	2	the	the	DET
admet-505	540	3	case	case	NOUN
admet-505	540	4	of	of	ADP
admet-505	540	5	ampholytes	ampholyte	NOUN
admet-505	540	6	,	,	PUNCT
admet-505	540	7	most	most	ADJ
admet-505	540	8	of	of	ADP
admet-505	540	9	the	the	DET
admet-505	540	10	variance	variance	NOUN
admet-505	540	11	is	be	AUX
admet-505	540	12	accounted	account	VERB
admet-505	540	13	by	by	ADP
admet-505	540	14	σβ2	σβ2	NOUN
admet-505	540	15	h	h	NOUN
admet-505	540	16	,	,	PUNCT
admet-505	540	17	while	while	SCONJ
admet-505	540	18	log	log	NOUN
admet-505	540	19	s0	s0	PROPN
admet-505	540	20	appears	appear	VERB
admet-505	540	21	to	to	PART
admet-505	540	22	be	be	AUX
admet-505	540	23	of	of	ADP
admet-505	540	24	minimal	minimal	ADJ
admet-505	540	25	importance	importance	NOUN
admet-505	540	26	(	(	PUNCT
admet-505	540	27	table	table	NOUN
admet-505	540	28	2	2	NUM
admet-505	540	29	)	)	PUNCT
admet-505	540	30	.	.	PUNCT
admet-505	541	1	figure	figure	NOUN
admet-505	541	2	8d	8d	PROPN
admet-505	541	3	shows	show	VERB
admet-505	541	4	the	the	DET
admet-505	541	5	final	final	ADJ
admet-505	541	6	best	good	ADJ
admet-505	541	7	-	-	PUNCT
admet-505	541	8	fit	fit	ADJ
admet-505	541	9	model	model	NOUN
admet-505	541	10	correlation	correlation	NOUN
admet-505	541	11	plot	plot	NOUN
admet-505	541	12	(	(	PUNCT
admet-505	541	13	although	although	SCONJ
admet-505	541	14	it	it	PRON
admet-505	541	15	is	be	AUX
admet-505	541	16	hardly	hardly	ADV
admet-505	541	17	better	well	ADJ
admet-505	541	18	than	than	ADP
admet-505	541	19	that	that	PRON
admet-505	541	20	in	in	ADP
admet-505	541	21	fig	fig	NOUN
admet-505	541	22	.	.	PUNCT
admet-505	542	1	8c	8c	NOUN
admet-505	542	2	)	)	PUNCT
admet-505	542	3	.	.	PUNCT
admet-505	543	1	the	the	DET
admet-505	543	2	four	four	NUM
admet-505	543	3	acid	acid	ADJ
admet-505	543	4	-	-	PUNCT
admet-505	543	5	base	base	NOUN
admet-505	543	6	group	group	NOUN
admet-505	543	7	analyses	analysis	NOUN
admet-505	543	8	were	be	AUX
admet-505	543	9	combined	combine	VERB
admet-505	543	10	into	into	ADP
admet-505	543	11	a	a	DET
admet-505	543	12	single	single	ADJ
admet-505	543	13	multiple	multiple	ADJ
admet-505	543	14	linear	linear	ADJ
admet-505	543	15	regression	regression	NOUN
admet-505	543	16	(	(	PUNCT
admet-505	543	17	mlr	mlr	NOUN
admet-505	543	18	)	)	PUNCT
admet-505	543	19	equation	equation	NOUN
admet-505	543	20	:	:	PUNCT
admet-505	543	21	log	log	VERB
admet-505	543	22	k	k	NOUN
admet-505	544	1	=	=	PRON
admet-505	544	2	{	{	PUNCT
admet-505	544	3	c0	c0	PROPN
admet-505	544	4	+	+	CCONJ
admet-505	544	5	c1	c1	PROPN
admet-505	544	6	·	·	PUNCT
admet-505	544	7	log	log	NOUN
admet-505	544	8	s0	s0	NOUN
admet-505	544	9	+	+	CCONJ
admet-505	544	10	c2	c2	PROPN
admet-505	544	11	·	·	PUNCT
admet-505	544	12	σα2	σα2	NOUN
admet-505	544	13	h	h	NOUN
admet-505	544	14	}	}	PUNCT
admet-505	544	15	·	·	PUNCT
admet-505	544	16	ia	ia	PROPN
admet-505	544	17	+	+	CCONJ
admet-505	544	18	{	{	PUNCT
admet-505	544	19	c3	c3	X
admet-505	544	20	+	+	CCONJ
admet-505	544	21	c4	c4	NOUN
admet-505	544	22	·	·	PUNCT
admet-505	544	23	log	log	NOUN
admet-505	544	24	s0	s0	NOUN
admet-505	544	25	}	}	PUNCT
admet-505	544	26	·	·	PUNCT
admet-505	544	27	ib	ib	NOUN
admet-505	544	28	+	+	CCONJ
admet-505	544	29	{	{	PUNCT
admet-505	544	30	c5	c5	PROPN
admet-505	544	31	+	+	CCONJ
admet-505	544	32	c6	c6	PROPN
admet-505	544	33	·	·	PUNCT
admet-505	544	34	log	log	PROPN
admet-505	544	35	s0	s0	NOUN
admet-505	544	36	+	+	CCONJ
admet-505	544	37	c7	c7	PROPN
admet-505	544	38	·	·	PUNCT
admet-505	544	39	σβ2	σβ2	VERB
admet-505	544	40	h	h	NOUN
admet-505	544	41	}	}	PUNCT
admet-505	544	42	·	·	PUNCT
admet-505	544	43	in	in	ADP
admet-505	544	44	+	+	CCONJ
admet-505	544	45	{	{	PUNCT
admet-505	544	46	c8	c8	PROPN
admet-505	544	47	+	+	CCONJ
admet-505	544	48	c9	c9	PROPN
admet-505	544	49	·	·	PUNCT
admet-505	544	50	log	log	NOUN
admet-505	544	51	s0	s0	PROPN
admet-505	544	52	+	+	CCONJ
admet-505	544	53	c10	c10	PROPN
admet-505	544	54	·	·	PUNCT
admet-505	544	55	σβ2	σβ2	VERB
admet-505	544	56	h	h	PROPN
admet-505	544	57	}	}	PUNCT
admet-505	544	58	·	·	PUNCT
admet-505	545	1	iz	iz	INTJ
admet-505	545	2	(	(	PUNCT
admet-505	545	3	15	15	NUM
admet-505	545	4	)	)	PUNCT
admet-505	545	5	table	table	NOUN
admet-505	545	6	2	2	NUM
admet-505	545	7	.	.	PUNCT
admet-505	545	8	prediction	prediction	NOUN
admet-505	545	9	of	of	ADP
admet-505	545	10	k	k	PROPN
admet-505	545	11	values	value	NOUN
admet-505	545	12	a	a	DET
admet-505	545	13	class	class	NOUN
admet-505	545	14	equation	equation	NOUN
admet-505	545	15	r2	r2	PROPN
admet-505	545	16	sd	sd	ADP
admet-505	545	17	f	f	PROPN
admet-505	545	18	n	n	PRON
admet-505	545	19	nonionizables	nonionizable	VERB
admet-505	545	20	log	log	VERB
admet-505	545	21	k	k	NOUN
admet-505	545	22	=	=	PUNCT
admet-505	546	1	0.479	0.479	NUM
admet-505	546	2	+	+	CCONJ
admet-505	546	3	0.249	0.249	NUM
admet-505	546	4	log	log	NOUN
admet-505	546	5	s0	s0	PROPN
admet-505	546	6	-0.201	-0.201	ADV
admet-505	546	7	σβ2	σβ2	VERB
admet-505	546	8	h	h	PROPN
admet-505	546	9	0.70	0.70	NUM
admet-505	546	10	0.15	0.15	NUM
admet-505	546	11	17	17	NUM
admet-505	546	12	17	17	NUM
admet-505	546	13	acids	acid	NOUN
admet-505	546	14	log	log	NOUN
admet-505	546	15	k	k	NOUN
admet-505	547	1	=	=	PUNCT
admet-505	548	1	1.011	1.011	NUM
admet-505	548	2	+	+	NUM
admet-505	548	3	0.417	0.417	NUM
admet-505	548	4	log	log	NOUN
admet-505	548	5	s0	s0	PROPN
admet-505	548	6	-0.692	-0.692	PUNCT
admet-505	548	7	σα2	σα2	NOUN
admet-505	548	8	h	h	NOUN
admet-505	548	9	0.71	0.71	NUM
admet-505	548	10	0.49	0.49	NUM
admet-505	548	11	54	54	NUM
admet-505	548	12	47	47	NUM
admet-505	548	13	bases	basis	NOUN
admet-505	548	14	log	log	VERB
admet-505	548	15	k	k	PROPN
admet-505	549	1	=	=	PUNCT
admet-505	550	1	1.228	1.228	NUM
admet-505	550	2	+	+	CCONJ
admet-505	550	3	0.542	0.542	NUM
admet-505	550	4	log	log	NOUN
admet-505	550	5	s0	s0	NOUN
admet-505	550	6	0.74	0.74	NUM
admet-505	550	7	0.57	0.57	NUM
admet-505	550	8	66	66	NUM
admet-505	550	9	25	25	NUM
admet-505	550	10	ampholytes	ampholyte	NOUN
admet-505	550	11	log	log	VERB
admet-505	550	12	k	k	NOUN
admet-505	550	13	=	=	PUNCT
admet-505	551	1	-0.122	-0.122	PUNCT
admet-505	552	1	+	+	NUM
admet-505	552	2	0.083	0.083	NUM
admet-505	552	3	log	log	NOUN
admet-505	552	4	s0	s0	PROPN
admet-505	552	5	-0.548	-0.548	PUNCT
admet-505	552	6	σβ2	σβ2	PROPN
admet-505	552	7	h	h	PROPN
admet-505	552	8	0.79	0.79	NUM
admet-505	552	9	0.10	0.10	NUM
admet-505	552	10	17	17	NUM
admet-505	552	11	12	12	NUM
admet-505	552	12	overall	overall	ADV
admet-505	552	13	based	base	VERB
admet-505	552	14	on	on	ADP
admet-505	552	15	eq	eq	ADP
admet-505	552	16	.	.	PUNCT
admet-505	553	1	(	(	PUNCT
admet-505	553	2	15	15	NUM
admet-505	553	3	)	)	PUNCT
admet-505	553	4	0.74	0.74	NUM
admet-505	553	5	0.44	0.44	NUM
admet-505	553	6	288	288	NUM
admet-505	553	7	101	101	NUM
admet-505	553	8	a	a	DET
admet-505	553	9	σα2h	σα2h	NOUN
admet-505	553	10	and	and	CCONJ
admet-505	553	11	σβ2h	σβ2h	PROPN
admet-505	553	12	are	be	AUX
admet-505	553	13	the	the	DET
admet-505	553	14	calculated	calculated	ADJ
admet-505	553	15	abraham	abraham	PROPN
admet-505	553	16	h	h	PROPN
admet-505	553	17	-	-	PUNCT
admet-505	553	18	bond	bond	NOUN
admet-505	553	19	total	total	ADJ
admet-505	553	20	acidity	acidity	NOUN
admet-505	553	21	and	and	CCONJ
admet-505	553	22	basicity	basicity	NOUN
admet-505	553	23	descriptors	descriptor	NOUN
admet-505	553	24	,	,	PUNCT
admet-505	553	25	resp	resp	NOUN
admet-505	553	26	.	.	PUNCT
admet-505	554	1	;	;	PUNCT
admet-505	554	2	r	r	NOUN
admet-505	554	3	2	2	NUM
admet-505	554	4	=	=	NUM
admet-505	554	5	squared	square	VERB
admet-505	554	6	multiple	multiple	ADJ
admet-505	554	7	correlation	correlation	NOUN
admet-505	554	8	coefficient	coefficient	NOUN
admet-505	554	9	;	;	PUNCT
admet-505	554	10	sd	sd	NOUN
admet-505	554	11	=	=	SYM
admet-505	554	12	standard	standard	ADJ
admet-505	554	13	deviation	deviation	NOUN
admet-505	554	14	in	in	ADP
admet-505	554	15	the	the	DET
admet-505	554	16	linear	linear	PROPN
admet-505	554	17	fit	fit	NOUN
admet-505	554	18	;	;	PUNCT
admet-505	554	19	f	f	X
admet-505	554	20	=	=	PUNCT
admet-505	554	21	measure	measure	NOUN
admet-505	554	22	of	of	ADP
admet-505	554	23	predictive	predictive	ADJ
admet-505	554	24	capability	capability	NOUN
admet-505	554	25	:	:	PUNCT
admet-505	554	26	how	how	SCONJ
admet-505	554	27	much	much	ADJ
admet-505	554	28	of	of	ADP
admet-505	554	29	the	the	DET
admet-505	554	30	variance	variance	NOUN
admet-505	554	31	is	be	AUX
admet-505	554	32	explained	explain	VERB
admet-505	554	33	by	by	ADP
admet-505	554	34	the	the	DET
admet-505	554	35	model	model	NOUN
admet-505	554	36	per	per	ADP
admet-505	554	37	parameter	parameter	NOUN
admet-505	554	38	;	;	PUNCT
admet-505	554	39	n	n	NOUN
admet-505	554	40	=	=	NOUN
admet-505	554	41	number	number	NOUN
admet-505	554	42	of	of	ADP
admet-505	554	43	k	k	PROPN
admet-505	554	44	values	value	NOUN
admet-505	554	45	used	use	VERB
admet-505	554	46	.	.	PUNCT
admet-505	555	1	alex	alex	PROPN
admet-505	555	2	avdeef	avdeef	PROPN
admet-505	555	3	admet	admet	PROPN
admet-505	555	4	&	&	CCONJ
admet-505	555	5	dmpk	dmpk	PROPN
admet-505	555	6	6(2	6(2	NUM
admet-505	555	7	)	)	PUNCT
admet-505	555	8	(	(	PUNCT
admet-505	555	9	2018	2018	NUM
admet-505	555	10	)	)	PUNCT
admet-505	555	11	105	105	NUM
admet-505	555	12	-	-	SYM
admet-505	555	13	139	139	NUM
admet-505	555	14	124	124	NUM
admet-505	555	15	figure	figure	NOUN
admet-505	555	16	8	8	NUM
admet-505	555	17	.	.	PUNCT
admet-505	556	1	correlations	correlation	NOUN
admet-505	556	2	between	between	ADP
admet-505	556	3	log	log	PROPN
admet-505	556	4	k	k	PROPN
admet-505	556	5	and	and	CCONJ
admet-505	556	6	(	(	PUNCT
admet-505	556	7	a	a	PRON
admet-505	556	8	)	)	PUNCT
admet-505	556	9	octanol	octanol	NOUN
admet-505	556	10	-	-	PUNCT
admet-505	556	11	water	water	NOUN
admet-505	556	12	partition	partition	NOUN
admet-505	556	13	coefficients	coefficient	NOUN
admet-505	556	14	,	,	PUNCT
admet-505	556	15	log	log	PROPN
admet-505	556	16	poct	poct	NOUN
admet-505	556	17	,	,	PUNCT
admet-505	556	18	(	(	PUNCT
admet-505	556	19	b	b	X
admet-505	556	20	)	)	PUNCT
admet-505	556	21	mcgowan	mcgowan	PROPN
admet-505	556	22	molecular	molecular	ADJ
admet-505	556	23	volume	volume	NOUN
admet-505	556	24	,	,	PUNCT
admet-505	556	25	vx	vx	PROPN
admet-505	556	26	,	,	PUNCT
admet-505	556	27	in	in	ADP
admet-505	556	28	units	unit	NOUN
admet-505	556	29	of	of	ADP
admet-505	556	30	0.01	0.01	NUM
admet-505	556	31	l·mol	l·mol	PROPN
admet-505	556	32	-1	-1	PUNCT
admet-505	556	33	(	(	PUNCT
admet-505	556	34	c	c	NOUN
admet-505	556	35	)	)	PUNCT
admet-505	556	36	intrinsic	intrinsic	ADJ
admet-505	556	37	solubility	solubility	NOUN
admet-505	556	38	,	,	PUNCT
admet-505	556	39	log	log	NOUN
admet-505	556	40	s0	s0	PROPN
admet-505	556	41	(	(	PUNCT
admet-505	556	42	molarity	molarity	NOUN
admet-505	556	43	)	)	PUNCT
admet-505	556	44	,	,	PUNCT
admet-505	556	45	and	and	CCONJ
admet-505	556	46	(	(	PUNCT
admet-505	556	47	d	d	NOUN
admet-505	556	48	)	)	PUNCT
admet-505	556	49	multiple	multiple	ADJ
admet-505	556	50	linear	linear	ADJ
admet-505	556	51	regression	regression	NOUN
admet-505	556	52	with	with	ADP
admet-505	556	53	data	datum	NOUN
admet-505	556	54	grouped	group	VERB
admet-505	556	55	according	accord	VERB
admet-505	556	56	to	to	ADP
admet-505	556	57	acid	acid	NOUN
admet-505	556	58	-	-	PUNCT
admet-505	556	59	base	base	NOUN
admet-505	556	60	classes	class	NOUN
admet-505	556	61	,	,	PUNCT
admet-505	556	62	using	use	VERB
admet-505	556	63	log	log	NOUN
admet-505	556	64	s0	s0	PROPN
admet-505	556	65	,	,	PUNCT
admet-505	556	66	σα2	σα2	NOUN
admet-505	556	67	h	h	NOUN
admet-505	556	68	,	,	PUNCT
admet-505	556	69	and	and	CCONJ
admet-505	556	70	σβ2	σβ2	NOUN
admet-505	556	71	h	h	NOUN
admet-505	556	72	as	as	ADP
admet-505	556	73	descriptors	descriptor	NOUN
admet-505	556	74	(	(	PUNCT
admet-505	556	75	cf	cf	NOUN
admet-505	556	76	.	.	NOUN
admet-505	556	77	,	,	PUNCT
admet-505	556	78	table	table	NOUN
admet-505	556	79	2	2	NUM
admet-505	556	80	)	)	PUNCT
admet-505	556	81	.	.	PUNCT
admet-505	557	1	the	the	DET
admet-505	557	2	best	well	ADV
admet-505	557	3	-	-	PUNCT
admet-505	557	4	fit	fit	ADJ
admet-505	557	5	mlr	mlr	NOUN
admet-505	557	6	coefficients	coefficient	NOUN
admet-505	557	7	,	,	PUNCT
admet-505	557	8	c0	c0	PROPN
admet-505	557	9	-	-	PUNCT
admet-505	557	10	c10	c10	PROPN
admet-505	557	11	are	be	AUX
admet-505	557	12	listed	list	VERB
admet-505	557	13	in	in	ADP
admet-505	557	14	table	table	NOUN
admet-505	557	15	2	2	NUM
admet-505	557	16	.	.	PUNCT
admet-505	558	1	the	the	DET
admet-505	558	2	combined	combine	VERB
admet-505	558	3	set	set	NOUN
admet-505	558	4	yielded	yield	VERB
admet-505	558	5	r2	r2	NOUN
admet-505	558	6	=	=	PUNCT
admet-505	558	7	0.74	0.74	NUM
admet-505	558	8	,	,	PUNCT
admet-505	558	9	sd	sd	ADP
admet-505	558	10	=	=	SYM
admet-505	558	11	0.44	0.44	NUM
admet-505	558	12	,	,	PUNCT
admet-505	558	13	f	f	X
admet-505	558	14	=	=	SYM
admet-505	558	15	288	288	NUM
admet-505	558	16	,	,	PUNCT
admet-505	558	17	n	n	NOUN
admet-505	558	18	=	=	SYM
admet-505	558	19	101	101	NUM
admet-505	558	20	.	.	PUNCT
admet-505	559	1	the	the	DET
admet-505	559	2	compounds	compound	NOUN
admet-505	559	3	with	with	ADP
admet-505	559	4	the	the	DET
admet-505	559	5	lowest	low	ADJ
admet-505	559	6	intrinsic	intrinsic	ADJ
admet-505	559	7	solubility	solubility	NOUN
admet-505	559	8	(	(	PUNCT
admet-505	559	9	e.g.	e.g.	ADV
admet-505	559	10	,	,	PUNCT
admet-505	559	11	nsc-639829	nsc-639829	NOUN
admet-505	559	12	,	,	PUNCT
admet-505	559	13	curcumin	curcumin	NOUN
admet-505	559	14	,	,	PUNCT
admet-505	559	15	glibenclamide	glibenclamide	NOUN
admet-505	559	16	)	)	PUNCT
admet-505	559	17	showed	show	VERB
admet-505	559	18	the	the	DET
admet-505	559	19	highest	high	ADJ
admet-505	559	20	variances	variance	NOUN
admet-505	559	21	,	,	PUNCT
admet-505	559	22	as	as	SCONJ
admet-505	559	23	indicated	indicate	VERB
admet-505	559	24	in	in	ADP
admet-505	559	25	figure	figure	NOUN
admet-505	559	26	8d	8d	NUM
admet-505	559	27	.	.	PUNCT
admet-505	560	1	the	the	DET
admet-505	560	2	erythromycin	erythromycin	NOUN
admet-505	560	3	outlier	outlier	NOUN
admet-505	560	4	may	may	AUX
admet-505	560	5	be	be	AUX
admet-505	560	6	due	due	ADJ
admet-505	560	7	to	to	ADP
admet-505	560	8	unaccounted	unaccounted	ADJ
admet-505	560	9	precipitation	precipitation	NOUN
admet-505	560	10	of	of	ADP
admet-505	560	11	the	the	DET
admet-505	560	12	drug	drug	NOUN
admet-505	560	13	-	-	PUNCT
admet-505	560	14	sds	sds	NOUN
admet-505	560	15	salt	salt	NOUN
admet-505	560	16	[	[	X
admet-505	560	17	61	61	NUM
admet-505	560	18	]	]	PUNCT
admet-505	560	19	.	.	PUNCT
admet-505	561	1	in	in	ADP
admet-505	561	2	sum	sum	NOUN
admet-505	561	3	,	,	PUNCT
admet-505	561	4	it	it	PRON
admet-505	561	5	appears	appear	VERB
admet-505	561	6	that	that	SCONJ
admet-505	561	7	the	the	DET
admet-505	561	8	combined	combined	ADJ
admet-505	561	9	quality	quality	NOUN
admet-505	561	10	of	of	ADP
admet-505	561	11	the	the	DET
admet-505	561	12	experimental	experimental	ADJ
admet-505	561	13	k	k	PROPN
admet-505	561	14	and	and	CCONJ
admet-505	561	15	s0	s0	PROPN
admet-505	561	16	data	datum	NOUN
admet-505	561	17	limited	limit	VERB
admet-505	561	18	further	further	ADJ
admet-505	561	19	improvements	improvement	NOUN
admet-505	561	20	of	of	ADP
admet-505	561	21	the	the	DET
admet-505	561	22	prediction	prediction	NOUN
admet-505	561	23	model	model	NOUN
admet-505	561	24	.	.	PUNCT
admet-505	562	1	in	in	ADP
admet-505	562	2	-	-	PUNCT
admet-505	562	3	depth	depth	NOUN
admet-505	562	4	treatment	treatment	NOUN
admet-505	562	5	of	of	ADP
admet-505	562	6	ph	ph	ADJ
admet-505	562	7	dependence	dependence	NOUN
admet-505	562	8	of	of	ADP
admet-505	562	9	k	k	PROPN
admet-505	562	10	values	value	NOUN
admet-505	562	11	the	the	DET
admet-505	562	12	data	datum	NOUN
admet-505	562	13	below	below	ADP
admet-505	562	14	the	the	DET
admet-505	562	15	cmc	cmc	NOUN
admet-505	562	16	for	for	ADP
admet-505	562	17	carvedilol	carvedilol	NOUN
admet-505	562	18	(	(	PUNCT
admet-505	562	19	fig	fig	NOUN
admet-505	562	20	.	.	PUNCT
admet-505	563	1	7b	7b	NOUN
admet-505	563	2	)	)	PUNCT
admet-505	563	3	and	and	CCONJ
admet-505	563	4	pg-300995	pg-300995	PROPN
admet-505	563	5	(	(	PUNCT
admet-505	563	6	fig	fig	NOUN
admet-505	563	7	.	.	PUNCT
admet-505	564	1	7e	7e	NUM
admet-505	564	2	)	)	PUNCT
admet-505	564	3	take	take	VERB
admet-505	564	4	on	on	ADP
admet-505	564	5	a	a	DET
admet-505	564	6	complex	complex	ADJ
admet-505	564	7	dependence	dependence	NOUN
admet-505	564	8	on	on	ADP
admet-505	564	9	ph	ph	PROPN
admet-505	564	10	and	and	CCONJ
admet-505	564	11	sds	sds	NOUN
admet-505	564	12	concentration	concentration	NOUN
admet-505	564	13	,	,	PUNCT
admet-505	564	14	and	and	CCONJ
admet-505	564	15	will	will	AUX
admet-505	564	16	be	be	AUX
admet-505	564	17	examined	examine	VERB
admet-505	564	18	here	here	ADV
admet-505	564	19	in	in	ADP
admet-505	564	20	detail	detail	NOUN
admet-505	564	21	.	.	PUNCT
admet-505	565	1	as	as	SCONJ
admet-505	565	2	the	the	DET
admet-505	565	3	sds	sds	PROPN
admet-505	565	4	decreases	decrease	VERB
admet-505	565	5	below	below	ADP
admet-505	565	6	the	the	DET
admet-505	565	7	cmc	cmc	NOUN
admet-505	565	8	,	,	PUNCT
admet-505	565	9	the	the	DET
admet-505	565	10	solubility	solubility	NOUN
admet-505	565	11	of	of	ADP
admet-505	565	12	the	the	DET
admet-505	565	13	two	two	NUM
admet-505	565	14	molecules	molecule	NOUN
admet-505	565	15	actually	actually	ADV
admet-505	565	16	increases	increase	VERB
admet-505	565	17	,	,	PUNCT
admet-505	565	18	in	in	ADP
admet-505	565	19	contrast	contrast	NOUN
admet-505	565	20	to	to	ADP
admet-505	565	21	all	all	DET
admet-505	565	22	the	the	DET
admet-505	565	23	preceding	precede	VERB
admet-505	565	24	examples	example	NOUN
admet-505	565	25	(	(	PUNCT
admet-505	565	26	figs	fig	NOUN
admet-505	565	27	.	.	PUNCT
admet-505	566	1	2	2	NUM
admet-505	566	2	-	-	SYM
admet-505	566	3	6	6	NUM
admet-505	566	4	)	)	PUNCT
admet-505	566	5	.	.	PUNCT
admet-505	567	1	this	this	PRON
admet-505	567	2	can	can	AUX
admet-505	567	3	be	be	AUX
admet-505	567	4	explained	explain	VERB
admet-505	567	5	by	by	ADP
admet-505	567	6	the	the	DET
admet-505	567	7	precipitation	precipitation	NOUN
admet-505	567	8	of	of	ADP
admet-505	567	9	salt	salt	NOUN
admet-505	567	10	formed	form	VERB
admet-505	567	11	between	between	ADP
admet-505	567	12	positively	positively	ADV
admet-505	567	13	charged	charge	VERB
admet-505	567	14	drug	drug	NOUN
admet-505	567	15	and	and	CCONJ
admet-505	567	16	the	the	DET
admet-505	567	17	sds	sds	PROPN
admet-505	567	18	anions	anion	NOUN
admet-505	567	19	,	,	PUNCT
admet-505	567	20	and	and	CCONJ
admet-505	567	21	confirmed	confirm	VERB
admet-505	567	22	by	by	ADP
admet-505	567	23	speciation	speciation	NOUN
admet-505	567	24	regression	regression	NOUN
admet-505	567	25	analysis	analysis	NOUN
admet-505	567	26	.	.	PUNCT
admet-505	568	1	the	the	DET
admet-505	568	2	same	same	ADJ
admet-505	568	3	may	may	AUX
admet-505	568	4	be	be	AUX
admet-505	568	5	taking	take	VERB
admet-505	568	6	place	place	NOUN
admet-505	568	7	for	for	ADP
admet-505	568	8	carbendazim	carbendazim	NOUN
admet-505	568	9	at	at	ADP
admet-505	568	10	ph	ph	ADJ
admet-505	568	11	2.05	2.05	NUM
admet-505	568	12	in	in	ADP
admet-505	568	13	admet	admet	PROPN
admet-505	568	14	&	&	CCONJ
admet-505	568	15	dmpk	dmpk	PROPN
admet-505	568	16	6(2	6(2	NUM
admet-505	568	17	)	)	PUNCT
admet-505	568	18	(	(	PUNCT
admet-505	568	19	2018	2018	NUM
admet-505	568	20	)	)	PUNCT
admet-505	568	21	105	105	NUM
admet-505	568	22	-	-	SYM
admet-505	568	23	139	139	NUM
admet-505	568	24	cocrystal	cocrystal	ADJ
admet-505	568	25	solubility	solubility	NOUN
admet-505	568	26	-	-	PUNCT
admet-505	568	27	ph	ph	VERB
admet-505	568	28	,	,	PUNCT
admet-505	568	29	drug	drug	NOUN
admet-505	568	30	solubilization	solubilization	NOUN
admet-505	568	31	capacity	capacity	NOUN
admet-505	568	32	of	of	ADP
admet-505	568	33	sds	sds	PROPN
admet-505	568	34	,	,	PUNCT
admet-505	568	35	mass	mass	ADJ
admet-505	568	36	action	action	NOUN
admet-505	568	37	model	model	NOUN
admet-505	568	38	doi	doi	PROPN
admet-505	568	39	:	:	PUNCT
admet-505	568	40	10.5599	10.5599	NUM
admet-505	568	41	/	/	SYM
admet-505	568	42	admet.505	admet.505	PROPN
admet-505	568	43	125	125	NUM
admet-505	568	44	figure	figure	NOUN
admet-505	568	45	7a	7a	NUM
admet-505	568	46	,	,	PUNCT
admet-505	568	47	but	but	CCONJ
admet-505	568	48	there	there	PRON
admet-505	568	49	was	be	VERB
admet-505	568	50	not	not	PART
admet-505	568	51	enough	enough	ADJ
admet-505	568	52	data	datum	NOUN
admet-505	568	53	reported	report	VERB
admet-505	568	54	to	to	PART
admet-505	568	55	test	test	VERB
admet-505	568	56	this	this	PRON
admet-505	568	57	.	.	PUNCT
admet-505	569	1	however	however	ADV
admet-505	569	2	,	,	PUNCT
admet-505	569	3	there	there	PRON
admet-505	569	4	were	be	VERB
admet-505	569	5	sufficient	sufficient	ADJ
admet-505	569	6	pre	pre	ADJ
admet-505	569	7	-	-	ADJ
admet-505	569	8	cmc	cmc	ADJ
admet-505	569	9	measurements	measurement	NOUN
admet-505	569	10	in	in	ADP
admet-505	569	11	the	the	DET
admet-505	569	12	cases	case	NOUN
admet-505	569	13	of	of	ADP
admet-505	569	14	carvedilol	carvedilol	NOUN
admet-505	569	15	and	and	CCONJ
admet-505	569	16	pg-300995	pg-300995	PROPN
admet-505	569	17	,	,	PUNCT
admet-505	569	18	particularly	particularly	ADV
admet-505	569	19	in	in	ADP
admet-505	569	20	the	the	DET
admet-505	569	21	latter	latter	ADJ
admet-505	569	22	case	case	NOUN
admet-505	569	23	.	.	PUNCT
admet-505	570	1	carvedilol	carvedilol	PROPN
admet-505	570	2	chakraborty	chakraborty	PROPN
admet-505	570	3	et	et	PROPN
admet-505	570	4	al	al	PROPN
admet-505	570	5	.	.	PUNCT
admet-505	571	1	[	[	X
admet-505	571	2	35	35	NUM
admet-505	571	3	]	]	PUNCT
admet-505	571	4	studied	study	VERB
admet-505	571	5	the	the	DET
admet-505	571	6	micellization	micellization	NOUN
admet-505	571	7	of	of	ADP
admet-505	571	8	carvedilol	carvedilol	NOUN
admet-505	571	9	at	at	ADP
admet-505	571	10	37	37	NUM
admet-505	571	11	°	°	SYM
admet-505	571	12	c	c	NOUN
admet-505	571	13	in	in	ADP
admet-505	571	14	the	the	DET
admet-505	571	15	ph	ph	ADJ
admet-505	571	16	1.2	1.2	NUM
admet-505	571	17	-	-	SYM
admet-505	571	18	7.2	7.2	NUM
admet-505	571	19	range	range	NOUN
admet-505	571	20	,	,	PUNCT
admet-505	571	21	where	where	SCONJ
admet-505	571	22	the	the	DET
admet-505	571	23	drug	drug	NOUN
admet-505	571	24	was	be	AUX
admet-505	571	25	largely	largely	ADV
admet-505	571	26	positively	positively	ADV
admet-505	571	27	charged	charge	VERB
admet-505	571	28	.	.	PUNCT
admet-505	572	1	the	the	DET
admet-505	572	2	authors	author	NOUN
admet-505	572	3	suggested	suggest	VERB
admet-505	572	4	that	that	SCONJ
admet-505	572	5	anionic	anionic	PROPN
admet-505	572	6	sds	sds	PROPN
admet-505	572	7	interacted	interact	VERB
admet-505	572	8	with	with	ADP
admet-505	572	9	the	the	DET
admet-505	572	10	cationic	cationic	ADJ
admet-505	572	11	drug	drug	NOUN
admet-505	572	12	species	specie	NOUN
admet-505	572	13	to	to	PART
admet-505	572	14	form	form	VERB
admet-505	572	15	an	an	DET
admet-505	572	16	insoluble	insoluble	ADJ
admet-505	572	17	drug	drug	NOUN
admet-505	572	18	salt	salt	NOUN
admet-505	572	19	.	.	PUNCT
admet-505	573	1	the	the	DET
admet-505	573	2	k	k	PROPN
admet-505	573	3	values	value	NOUN
admet-505	573	4	(	(	PUNCT
admet-505	573	5	fig	fig	NOUN
admet-505	573	6	.	.	PUNCT
admet-505	574	1	7b	7b	NOUN
admet-505	574	2	)	)	PUNCT
admet-505	574	3	did	do	AUX
admet-505	574	4	not	not	PART
admet-505	574	5	change	change	VERB
admet-505	574	6	across	across	ADP
admet-505	574	7	the	the	DET
admet-505	574	8	ph	ph	ADJ
admet-505	574	9	range	range	NOUN
admet-505	574	10	considered	consider	VERB
admet-505	574	11	,	,	PUNCT
admet-505	574	12	which	which	PRON
admet-505	574	13	is	be	AUX
admet-505	574	14	expected	expect	VERB
admet-505	574	15	if	if	SCONJ
admet-505	574	16	only	only	ADV
admet-505	574	17	the	the	DET
admet-505	574	18	neutral	neutral	ADJ
admet-505	574	19	form	form	NOUN
admet-505	574	20	of	of	ADP
admet-505	574	21	the	the	DET
admet-505	574	22	drug	drug	NOUN
admet-505	574	23	were	be	AUX
admet-505	574	24	solubilized	solubilize	VERB
admet-505	574	25	by	by	ADP
admet-505	574	26	sds	sds	PROPN
admet-505	574	27	micelles	micelle	NOUN
admet-505	574	28	.	.	PUNCT
admet-505	575	1	there	there	PRON
admet-505	575	2	were	be	VERB
admet-505	575	3	not	not	PART
admet-505	575	4	a	a	DET
admet-505	575	5	lot	lot	NOUN
admet-505	575	6	of	of	ADP
admet-505	575	7	data	datum	NOUN
admet-505	575	8	in	in	ADP
admet-505	575	9	the	the	DET
admet-505	575	10	pre	pre	ADJ
admet-505	575	11	-	-	ADJ
admet-505	575	12	cmc	cmc	ADJ
admet-505	575	13	region	region	NOUN
admet-505	575	14	,	,	PUNCT
admet-505	575	15	but	but	CCONJ
admet-505	575	16	it	it	PRON
admet-505	575	17	was	be	AUX
admet-505	575	18	possible	possible	ADJ
admet-505	575	19	to	to	PART
admet-505	575	20	estimate	estimate	VERB
admet-505	575	21	log	log	PROPN
admet-505	575	22	ksp	ksp	PROPN
admet-505	575	23	bh.cl	bh.cl	PROPN
admet-505	575	24	=	=	PROPN
admet-505	575	25	-3.88	-3.88	X
admet-505	575	26	(	(	PUNCT
admet-505	575	27	from	from	ADP
admet-505	575	28	surfactant	surfactant	NOUN
admet-505	575	29	-	-	PUNCT
admet-505	575	30	free	free	ADJ
admet-505	575	31	solubility	solubility	NOUN
admet-505	575	32	data	datum	NOUN
admet-505	575	33	)	)	PUNCT
admet-505	575	34	and	and	CCONJ
admet-505	575	35	log	log	VERB
admet-505	575	36	ksp	ksp	PROPN
admet-505	575	37	bh.sds	bh.sds	PROPN
admet-505	575	38	=	=	SYM
admet-505	575	39	-5.52	-5.52	PROPN
admet-505	575	40	(	(	PUNCT
admet-505	575	41	from	from	ADP
admet-505	575	42	data	datum	NOUN
admet-505	575	43	at	at	ADP
admet-505	575	44	[	[	X
admet-505	575	45	sds]tot	sds]tot	NOUN
admet-505	575	46	=	=	SYM
admet-505	575	47	5	5	NUM
admet-505	575	48	mm	mm	NOUN
admet-505	575	49	)	)	PUNCT
admet-505	575	50	.	.	PUNCT
admet-505	576	1	pg-300995	pg-300995	PROPN
admet-505	576	2	there	there	PRON
admet-505	576	3	were	be	VERB
admet-505	576	4	ample	ample	ADJ
admet-505	576	5	data	datum	NOUN
admet-505	576	6	,	,	PUNCT
admet-505	576	7	both	both	PRON
admet-505	576	8	preand	preand	VERB
admet-505	576	9	post	post	ADJ
admet-505	576	10	-	-	NOUN
admet-505	576	11	cmc	cmc	ADJ
admet-505	576	12	,	,	PUNCT
admet-505	576	13	for	for	ADP
admet-505	576	14	the	the	DET
admet-505	576	15	case	case	NOUN
admet-505	576	16	of	of	ADP
admet-505	576	17	pg-300995	pg-300995	PROPN
admet-505	576	18	(	(	PUNCT
admet-505	576	19	2-(2	2-(2	NOUN
admet-505	576	20	-	-	PUNCT
admet-505	576	21	thienyl)-1h	thienyl)-1h	NOUN
admet-505	576	22	-	-	PUNCT
admet-505	576	23	imidazo[4,5b]pyridine	imidazo[4,5b]pyridine	NOUN
admet-505	576	24	)	)	PUNCT
admet-505	576	25	reported	report	VERB
admet-505	576	26	by	by	ADP
admet-505	576	27	jain	jain	PROPN
admet-505	576	28	et	et	PROPN
admet-505	576	29	al	al	PROPN
admet-505	576	30	.	.	PUNCT
admet-505	577	1	[	[	X
admet-505	577	2	49	49	NUM
admet-505	577	3	]	]	PUNCT
admet-505	577	4	to	to	PART
admet-505	577	5	allow	allow	VERB
admet-505	577	6	for	for	ADP
admet-505	577	7	further	further	ADJ
admet-505	577	8	analyses	analysis	NOUN
admet-505	577	9	here	here	ADV
admet-505	577	10	.	.	PUNCT
admet-505	578	1	the	the	DET
admet-505	578	2	solubility	solubility	NOUN
admet-505	578	3	-	-	PUNCT
admet-505	578	4	ph	ph	NOUN
admet-505	578	5	data	datum	NOUN
admet-505	578	6	at	at	ADP
admet-505	578	7	25	25	NUM
admet-505	578	8	°	°	NOUN
admet-505	578	9	c	c	NOUN
admet-505	578	10	,	,	PUNCT
admet-505	578	11	i	i	PRON
admet-505	578	12	=	=	PROPN
admet-505	578	13	0.2	0.2	NUM
admet-505	578	14	m	m	PROPN
admet-505	578	15	,	,	PUNCT
admet-505	578	16	in	in	ADP
admet-505	578	17	sds	sds	NOUN
admet-505	578	18	-	-	PUNCT
admet-505	578	19	free	free	ADJ
admet-505	578	20	,	,	PUNCT
admet-505	578	21	buffered	buffer	VERB
admet-505	578	22	solutions	solution	NOUN
admet-505	578	23	[	[	X
admet-505	578	24	60	60	NUM
admet-505	578	25	]	]	PUNCT
admet-505	578	26	were	be	AUX
admet-505	578	27	re	re	VERB
admet-505	578	28	-	-	VERB
admet-505	578	29	analyzed	analyze	VERB
admet-505	578	30	using	use	VERB
admet-505	578	31	pdisol	pdisol	ADJ
admet-505	578	32	-	-	PUNCT
admet-505	578	33	x	x	NOUN
admet-505	578	34	,	,	PUNCT
admet-505	578	35	to	to	PART
admet-505	578	36	obtain	obtain	VERB
admet-505	578	37	pka	pka	NOUN
admet-505	578	38	=	=	PUNCT
admet-505	578	39	3.59	3.59	NUM
admet-505	578	40	±	±	NOUN
admet-505	578	41	0.06	0.06	NUM
admet-505	578	42	,	,	PUNCT
admet-505	578	43	log	log	NOUN
admet-505	578	44	s0	s0	NOUN
admet-505	578	45	=	=	PUNCT
admet-505	578	46	-3.59	-3.59	X
admet-505	578	47	±	±	NUM
admet-505	578	48	0.03	0.03	NUM
admet-505	578	49	,	,	PUNCT
admet-505	578	50	and	and	CCONJ
admet-505	578	51	log	log	VERB
admet-505	578	52	ksp	ksp	PROPN
admet-505	578	53	bh.cl	bh.cl	PROPN
admet-505	578	54	=	=	SYM
admet-505	578	55	-2.12	-2.12	NUM
admet-505	578	56	±	±	NUM
admet-505	578	57	0.11	0.11	NUM
admet-505	578	58	,	,	PUNCT
admet-505	578	59	gof	gof	NOUN
admet-505	578	60	=	=	PUNCT
admet-505	578	61	0.84	0.84	NUM
admet-505	578	62	,	,	PUNCT
admet-505	578	63	n	n	NOUN
admet-505	578	64	=	=	SYM
admet-505	578	65	11	11	NUM
admet-505	578	66	.	.	PUNCT
admet-505	579	1	jain	jain	PROPN
admet-505	579	2	et	et	PROPN
admet-505	579	3	al.[49	al.[49	PROPN
admet-505	579	4	]	]	PUNCT
admet-505	579	5	had	have	AUX
admet-505	579	6	proposed	propose	VERB
admet-505	579	7	that	that	SCONJ
admet-505	579	8	the	the	DET
admet-505	579	9	positively	positively	ADV
admet-505	579	10	-	-	PUNCT
admet-505	579	11	charged	charge	VERB
admet-505	579	12	drug	drug	NOUN
admet-505	579	13	precipitates	precipitate	NOUN
admet-505	579	14	as	as	ADP
admet-505	579	15	the	the	DET
admet-505	579	16	(	(	PUNCT
admet-505	579	17	estolate	estolate	ADJ
admet-505	579	18	)	)	PUNCT
admet-505	579	19	salt	salt	NOUN
admet-505	579	20	with	with	ADP
admet-505	579	21	anionic	anionic	ADJ
admet-505	579	22	sds	sds	PROPN
admet-505	579	23	in	in	ADP
admet-505	579	24	the	the	DET
admet-505	579	25	pre	pre	ADJ
admet-505	579	26	-	-	ADJ
admet-505	579	27	cmc	cmc	ADJ
admet-505	579	28	region	region	NOUN
admet-505	579	29	.	.	PUNCT
admet-505	580	1	erythromycin	erythromycin	PROPN
admet-505	580	2	is	be	AUX
admet-505	580	3	another	another	DET
admet-505	580	4	rare	rare	ADJ
admet-505	580	5	example	example	NOUN
admet-505	580	6	of	of	ADP
admet-505	580	7	such	such	DET
admet-505	580	8	an	an	DET
admet-505	580	9	estolate	estolate	ADJ
admet-505	580	10	salt	salt	NOUN
admet-505	580	11	formation	formation	NOUN
admet-505	580	12	[	[	X
admet-505	580	13	61	61	NUM
admet-505	580	14	]	]	PUNCT
admet-505	580	15	.	.	PUNCT
admet-505	581	1	however	however	ADV
admet-505	581	2	,	,	PUNCT
admet-505	581	3	the	the	DET
admet-505	581	4	solubilization	solubilization	NOUN
admet-505	581	5	of	of	ADP
admet-505	581	6	the	the	DET
admet-505	581	7	salt	salt	NOUN
admet-505	581	8	is	be	AUX
admet-505	581	9	not	not	PART
admet-505	581	10	evident	evident	ADJ
admet-505	581	11	in	in	ADP
admet-505	581	12	figure	figure	NOUN
admet-505	581	13	4b	4b	PROPN
admet-505	581	14	.	.	PUNCT
admet-505	582	1	it	it	PRON
admet-505	582	2	is	be	AUX
admet-505	582	3	estimated	estimate	VERB
admet-505	582	4	that	that	SCONJ
admet-505	582	5	the	the	DET
admet-505	582	6	solution	solution	NOUN
admet-505	582	7	ph	ph	NOUN
admet-505	582	8	is	be	AUX
admet-505	582	9	9.7	9.7	NUM
admet-505	582	10	(	(	PUNCT
admet-505	582	11	not	not	PART
admet-505	582	12	reported	report	VERB
admet-505	582	13	by	by	ADP
admet-505	582	14	bhat	bhat	PROPN
admet-505	582	15	et	et	PROPN
admet-505	582	16	al	al	PROPN
admet-505	582	17	.	.	PUNCT
admet-505	583	1	[	[	X
admet-505	583	2	37	37	NUM
admet-505	583	3	]	]	NUM
admet-505	583	4	)	)	PUNCT
admet-505	583	5	.	.	PUNCT
admet-505	584	1	the	the	DET
admet-505	584	2	pg-300995	pg-300995	PROPN
admet-505	584	3	data	datum	NOUN
admet-505	584	4	across	across	ADP
admet-505	584	5	the	the	DET
admet-505	584	6	whole	whole	ADJ
admet-505	584	7	range	range	NOUN
admet-505	584	8	of	of	ADP
admet-505	584	9	sds	sds	PROPN
admet-505	584	10	concentrations	concentration	NOUN
admet-505	584	11	were	be	AUX
admet-505	584	12	analyzed	analyze	VERB
admet-505	584	13	by	by	ADP
admet-505	584	14	the	the	DET
admet-505	584	15	mass	mass	PROPN
admet-505	584	16	action	action	NOUN
admet-505	584	17	model	model	NOUN
admet-505	584	18	,	,	PUNCT
admet-505	584	19	employing	employ	VERB
admet-505	584	20	one	one	NUM
admet-505	584	21	heterogeneous	heterogeneous	ADJ
admet-505	584	22	and	and	CCONJ
admet-505	584	23	three	three	NUM
admet-505	584	24	homogeneous	homogeneous	ADJ
admet-505	584	25	equilibrium	equilibrium	NOUN
admet-505	584	26	equations	equation	NOUN
admet-505	584	27	.	.	PUNCT
admet-505	585	1	the	the	DET
admet-505	585	2	drug	drug	NOUN
admet-505	585	3	is	be	AUX
admet-505	585	4	uncharged	uncharged	ADJ
admet-505	585	5	at	at	ADP
admet-505	585	6	ph	ph	ADJ
admet-505	585	7	7	7	NUM
admet-505	585	8	,	,	PUNCT
admet-505	585	9	and	and	CCONJ
admet-505	585	10	the	the	DET
admet-505	585	11	micellization	micellization	NOUN
admet-505	585	12	behavior	behavior	NOUN
admet-505	585	13	is	be	AUX
admet-505	585	14	relatively	relatively	ADV
admet-505	585	15	simple	simple	ADJ
admet-505	585	16	.	.	PUNCT
admet-505	586	1	figure	figure	NOUN
admet-505	586	2	9a	9a	NOUN
admet-505	586	3	shows	show	VERB
admet-505	586	4	the	the	DET
admet-505	586	5	drug	drug	NOUN
admet-505	586	6	solubility	solubility	NOUN
admet-505	586	7	as	as	ADP
admet-505	586	8	a	a	DET
admet-505	586	9	function	function	NOUN
admet-505	586	10	[	[	X
admet-505	586	11	sds]tot	sds]tot	NOUN
admet-505	586	12	.	.	PUNCT
admet-505	587	1	the	the	DET
admet-505	587	2	red	red	ADJ
admet-505	587	3	curve	curve	NOUN
admet-505	587	4	was	be	AUX
admet-505	587	5	calculated	calculate	VERB
admet-505	587	6	using	use	VERB
admet-505	587	7	the	the	DET
admet-505	587	8	mechanistic	mechanistic	ADJ
admet-505	587	9	model	model	NOUN
admet-505	587	10	described	describe	VERB
admet-505	587	11	by	by	ADP
admet-505	587	12	eqs	eqs	PROPN
admet-505	587	13	.	.	PROPN
admet-505	588	1	(	(	PUNCT
admet-505	588	2	2)-(4	2)-(4	NUM
admet-505	588	3	)	)	PUNCT
admet-505	588	4	,	,	PUNCT
admet-505	588	5	with	with	ADP
admet-505	588	6	n	n	NOUN
admet-505	588	7	=	=	SYM
admet-505	588	8	2	2	NUM
admet-505	588	9	.	.	PUNCT
admet-505	589	1	(	(	PUNCT
admet-505	589	2	this	this	PRON
admet-505	589	3	is	be	AUX
admet-505	589	4	nearly	nearly	ADV
admet-505	589	5	,	,	PUNCT
admet-505	589	6	but	but	CCONJ
admet-505	589	7	not	not	PART
admet-505	589	8	precisely	precisely	ADV
admet-505	589	9	,	,	PUNCT
admet-505	589	10	the	the	DET
admet-505	589	11	same	same	ADJ
admet-505	589	12	as	as	ADP
admet-505	589	13	the	the	DET
admet-505	589	14	empirical	empirical	ADJ
admet-505	589	15	fit	fit	NOUN
admet-505	589	16	of	of	ADP
admet-505	589	17	the	the	DET
admet-505	589	18	ph	ph	ADJ
admet-505	589	19	7	7	NUM
admet-505	589	20	curve	curve	NOUN
admet-505	589	21	in	in	ADP
admet-505	589	22	figure	figure	NOUN
admet-505	589	23	7e	7e	NUM
admet-505	589	24	.	.	PUNCT
admet-505	589	25	)	)	PUNCT
admet-505	590	1	the	the	DET
admet-505	590	2	best	well	ADV
admet-505	590	3	-	-	PUNCT
admet-505	590	4	fit	fit	ADJ
admet-505	590	5	constants	constant	NOUN
admet-505	590	6	are	be	AUX
admet-505	590	7	summarized	summarize	VERB
admet-505	590	8	in	in	ADP
admet-505	590	9	the	the	DET
admet-505	590	10	box	box	NOUN
admet-505	590	11	in	in	ADP
admet-505	590	12	figure	figure	NOUN
admet-505	590	13	9c	9c	NUM
admet-505	590	14	.	.	PUNCT
admet-505	591	1	figure	figure	NOUN
admet-505	591	2	9b	9b	PROPN
admet-505	591	3	shows	show	VERB
admet-505	591	4	the	the	DET
admet-505	591	5	underlying	underlie	VERB
admet-505	591	6	reactant	reactant	NOUN
admet-505	591	7	concentrations	concentration	NOUN
admet-505	591	8	.	.	PUNCT
admet-505	592	1	these	these	DET
admet-505	592	2	concentrations	concentration	NOUN
admet-505	592	3	largely	largely	ADV
admet-505	592	4	follow	follow	VERB
admet-505	592	5	the	the	DET
admet-505	592	6	pattern	pattern	NOUN
admet-505	592	7	shown	show	VERB
admet-505	592	8	in	in	ADP
admet-505	592	9	figure	figure	NOUN
admet-505	592	10	1a	1a	NOUN
admet-505	592	11	.	.	PUNCT
admet-505	593	1	the	the	DET
admet-505	593	2	solubilization	solubilization	NOUN
admet-505	593	3	of	of	ADP
admet-505	593	4	uncharged	uncharged	ADJ
admet-505	593	5	drug	drug	NOUN
admet-505	593	6	lowers	lower	VERB
admet-505	593	7	the	the	DET
admet-505	593	8	cmc	cmc	NOUN
admet-505	593	9	to	to	ADP
admet-505	593	10	3.2	3.2	NUM
admet-505	593	11	mm	mm	NOUN
admet-505	593	12	.	.	PUNCT
admet-505	594	1	this	this	DET
admet-505	594	2	relatively	relatively	ADV
admet-505	594	3	simple	simple	ADJ
admet-505	594	4	pattern	pattern	NOUN
admet-505	594	5	of	of	ADP
admet-505	594	6	concentrations	concentration	NOUN
admet-505	594	7	is	be	AUX
admet-505	594	8	expected	expect	VERB
admet-505	594	9	to	to	PART
admet-505	594	10	be	be	AUX
admet-505	594	11	repeated	repeat	VERB
admet-505	594	12	in	in	ADP
admet-505	594	13	the	the	DET
admet-505	594	14	examples	example	NOUN
admet-505	594	15	in	in	ADP
admet-505	594	16	figures	figure	NOUN
admet-505	594	17	2	2	NUM
admet-505	594	18	-	-	SYM
admet-505	594	19	6	6	NUM
admet-505	594	20	,	,	PUNCT
admet-505	594	21	where	where	SCONJ
admet-505	594	22	the	the	DET
admet-505	594	23	drug	drug	NOUN
admet-505	594	24	in	in	ADP
admet-505	594	25	solution	solution	NOUN
admet-505	594	26	is	be	AUX
admet-505	594	27	predominantly	predominantly	ADV
admet-505	594	28	in	in	ADP
admet-505	594	29	the	the	DET
admet-505	594	30	uncharged	uncharged	ADJ
admet-505	594	31	state	state	NOUN
admet-505	594	32	.	.	PUNCT
admet-505	595	1	however	however	ADV
admet-505	595	2	,	,	PUNCT
admet-505	595	3	the	the	DET
admet-505	595	4	data	data	NOUN
admet-505	595	5	patterns	pattern	NOUN
admet-505	595	6	for	for	ADP
admet-505	595	7	pg-300995	pg-300995	NOUN
admet-505	595	8	at	at	ADP
admet-505	595	9	ph	ph	PROPN
admet-505	595	10	1	1	NUM
admet-505	595	11	-	-	SYM
admet-505	595	12	3	3	NUM
admet-505	595	13	are	be	AUX
admet-505	595	14	quite	quite	ADV
admet-505	595	15	different	different	ADJ
admet-505	595	16	,	,	PUNCT
admet-505	595	17	where	where	SCONJ
admet-505	595	18	the	the	DET
admet-505	595	19	drug	drug	NOUN
admet-505	595	20	in	in	ADP
admet-505	595	21	solution	solution	NOUN
admet-505	595	22	is	be	AUX
admet-505	595	23	predominantly	predominantly	ADV
admet-505	595	24	positively	positively	ADV
admet-505	595	25	charged	charge	VERB
admet-505	595	26	.	.	PUNCT
admet-505	596	1	one	one	NUM
admet-505	596	2	of	of	ADP
admet-505	596	3	the	the	DET
admet-505	596	4	independent	independent	ADJ
admet-505	596	5	variables	variable	NOUN
admet-505	596	6	in	in	ADP
admet-505	596	7	the	the	DET
admet-505	596	8	mass	mass	ADJ
admet-505	596	9	action	action	NOUN
admet-505	596	10	calculations	calculation	NOUN
admet-505	596	11	is	be	AUX
admet-505	596	12	the	the	DET
admet-505	596	13	actual	actual	ADJ
admet-505	596	14	weight	weight	NOUN
admet-505	596	15	of	of	ADP
admet-505	596	16	the	the	DET
admet-505	596	17	api	api	NOUN
admet-505	596	18	added	add	VERB
admet-505	596	19	to	to	ADP
admet-505	596	20	solution	solution	NOUN
admet-505	596	21	.	.	PUNCT
admet-505	597	1	provided	provide	VERB
admet-505	597	2	enough	enough	ADJ
admet-505	597	3	solid	solid	ADJ
admet-505	597	4	is	be	AUX
admet-505	597	5	added	add	VERB
admet-505	597	6	to	to	PART
admet-505	597	7	maintain	maintain	VERB
admet-505	597	8	a	a	DET
admet-505	597	9	saturated	saturated	ADJ
admet-505	597	10	solution	solution	NOUN
admet-505	597	11	,	,	PUNCT
admet-505	597	12	knowledge	knowledge	NOUN
admet-505	597	13	of	of	ADP
admet-505	597	14	the	the	DET
admet-505	597	15	exact	exact	ADJ
admet-505	597	16	weight	weight	NOUN
admet-505	597	17	is	be	AUX
admet-505	597	18	not	not	PART
admet-505	597	19	critical	critical	ADJ
admet-505	597	20	for	for	ADP
admet-505	597	21	simple	simple	ADJ
admet-505	597	22	solubilization	solubilization	NOUN
admet-505	597	23	reactions	reaction	NOUN
admet-505	597	24	in	in	ADP
admet-505	597	25	drug	drug	NOUN
admet-505	597	26	-	-	PUNCT
admet-505	597	27	saturated	saturate	VERB
admet-505	597	28	solutions	solution	NOUN
admet-505	597	29	under	under	ADP
admet-505	597	30	conditions	condition	NOUN
admet-505	597	31	where	where	SCONJ
admet-505	597	32	the	the	DET
admet-505	597	33	drug	drug	NOUN
admet-505	597	34	is	be	AUX
admet-505	597	35	uncharged	uncharged	ADJ
admet-505	597	36	(	(	PUNCT
admet-505	597	37	i.e.	i.e.	X
admet-505	597	38	,	,	PUNCT
admet-505	597	39	at	at	ADP
admet-505	597	40	ph	ph	NOUN
admet-505	597	41	7	7	NUM
admet-505	597	42	)	)	PUNCT
admet-505	597	43	.	.	PUNCT
admet-505	598	1	most	most	ADJ
admet-505	598	2	publications	publication	NOUN
admet-505	598	3	simply	simply	ADV
admet-505	598	4	state	state	VERB
admet-505	598	5	that	that	SCONJ
admet-505	598	6	“	"	PUNCT
admet-505	598	7	excess	excess	ADJ
admet-505	598	8	solid	solid	NOUN
admet-505	598	9	”	"	PUNCT
admet-505	598	10	was	be	AUX
admet-505	598	11	added	add	VERB
admet-505	598	12	in	in	ADP
admet-505	598	13	the	the	DET
admet-505	598	14	solubility	solubility	NOUN
admet-505	598	15	assay	assay	VERB
admet-505	598	16	.	.	PUNCT
admet-505	599	1	the	the	DET
admet-505	599	2	pg-300995	pg-300995	PROPN
admet-505	599	3	publication	publication	NOUN
admet-505	599	4	falls	fall	VERB
admet-505	599	5	into	into	ADP
admet-505	599	6	this	this	DET
admet-505	599	7	category	category	NOUN
admet-505	599	8	.	.	PUNCT
admet-505	600	1	however	however	ADV
admet-505	600	2	,	,	PUNCT
admet-505	600	3	at	at	ADP
admet-505	600	4	ph	ph	PROPN
admet-505	600	5	1	1	NUM
admet-505	600	6	-	-	SYM
admet-505	600	7	3	3	NUM
admet-505	600	8	,	,	PUNCT
admet-505	600	9	the	the	DET
admet-505	600	10	pg-300995	pg-300995	PROPN
admet-505	600	11	reactions	reaction	NOUN
admet-505	600	12	are	be	AUX
admet-505	600	13	not	not	PART
admet-505	600	14	simple	simple	ADJ
admet-505	600	15	.	.	PUNCT
admet-505	601	1	when	when	SCONJ
admet-505	601	2	the	the	DET
admet-505	601	3	cationic	cationic	ADJ
admet-505	601	4	drug	drug	NOUN
admet-505	601	5	,	,	PUNCT
admet-505	601	6	bh+	bh+	NOUN
admet-505	601	7	,	,	PUNCT
admet-505	601	8	forms	form	VERB
admet-505	601	9	a	a	DET
admet-505	601	10	salt	salt	NOUN
admet-505	601	11	precipitate	precipitate	NOUN
admet-505	601	12	with	with	ADP
admet-505	601	13	sds-	sds-	ADV
admet-505	601	14	,	,	PUNCT
admet-505	601	15	then	then	ADV
admet-505	601	16	it	it	PRON
admet-505	601	17	is	be	AUX
admet-505	601	18	necessary	necessary	ADJ
admet-505	601	19	to	to	PART
admet-505	601	20	provide	provide	VERB
admet-505	601	21	the	the	DET
admet-505	601	22	exact	exact	ADJ
admet-505	601	23	analytical	analytical	ADJ
admet-505	601	24	weight	weight	NOUN
admet-505	601	25	of	of	ADP
admet-505	601	26	the	the	DET
admet-505	601	27	api	api	NOUN
admet-505	601	28	for	for	ADP
admet-505	601	29	the	the	DET
admet-505	601	30	calculation	calculation	NOUN
admet-505	601	31	.	.	PUNCT
admet-505	602	1	figure	figure	NOUN
admet-505	602	2	10a	10a	PROPN
admet-505	602	3	shows	show	VERB
admet-505	602	4	the	the	DET
admet-505	602	5	drug	drug	NOUN
admet-505	602	6	solubility	solubility	NOUN
admet-505	602	7	at	at	ADP
admet-505	602	8	ph	ph	PROPN
admet-505	602	9	1	1	NUM
admet-505	602	10	as	as	ADP
admet-505	602	11	a	a	DET
admet-505	602	12	function	function	NOUN
admet-505	602	13	[	[	X
admet-505	602	14	sds]tot	sds]tot	NOUN
admet-505	602	15	.	.	PUNCT
admet-505	603	1	three	three	NUM
admet-505	603	2	different	different	ADJ
admet-505	603	3	[	[	X
admet-505	603	4	pg]tot	pg]tot	X
admet-505	603	5	were	be	AUX
admet-505	603	6	tested	test	VERB
admet-505	603	7	in	in	ADP
admet-505	603	8	the	the	DET
admet-505	603	9	mass	mass	ADJ
admet-505	603	10	action	action	NOUN
admet-505	603	11	calculations	calculation	NOUN
admet-505	603	12	:	:	PUNCT
admet-505	603	13	15	15	NUM
admet-505	603	14	,	,	PUNCT
admet-505	603	15	30	30	NUM
admet-505	603	16	,	,	PUNCT
admet-505	603	17	and	and	CCONJ
admet-505	603	18	38	38	NUM
admet-505	603	19	mm	mm	NOUN
admet-505	603	20	(	(	PUNCT
admet-505	603	21	solid	solid	ADJ
admet-505	603	22	,	,	PUNCT
admet-505	603	23	dot	dot	NOUN
admet-505	603	24	,	,	PUNCT
admet-505	603	25	dash	dash	NOUN
admet-505	603	26	curves	curve	NOUN
admet-505	603	27	,	,	PUNCT
admet-505	603	28	resp	resp	NOUN
admet-505	603	29	.	.	PUNCT
admet-505	603	30	)	)	PUNCT
admet-505	603	31	.	.	PUNCT
admet-505	604	1	above	above	ADP
admet-505	604	2	the	the	DET
admet-505	604	3	cmc	cmc	NOUN
admet-505	604	4	(	(	PUNCT
admet-505	604	5	estimated	estimate	VERB
admet-505	604	6	at	at	ADP
admet-505	604	7	17	17	NUM
admet-505	604	8	mm	mm	NOUN
admet-505	604	9	)	)	PUNCT
admet-505	604	10	,	,	PUNCT
admet-505	604	11	it	it	PRON
admet-505	604	12	is	be	AUX
admet-505	604	13	not	not	PART
admet-505	604	14	critical	critical	ADJ
admet-505	604	15	to	to	ADP
admet-505	604	16	the	the	DET
admet-505	604	17	calculation	calculation	NOUN
admet-505	604	18	that	that	PRON
admet-505	604	19	the	the	DET
admet-505	604	20	actual	actual	ADJ
admet-505	604	21	[	[	X
admet-505	604	22	pg]tot	pg]tot	ADP
admet-505	604	23	be	be	AUX
admet-505	604	24	provided	provide	VERB
admet-505	604	25	.	.	PUNCT
admet-505	605	1	“	"	PUNCT
admet-505	605	2	excess	excess	NOUN
admet-505	605	3	”	"	PUNCT
admet-505	605	4	is	be	AUX
admet-505	605	5	sufficient	sufficient	ADJ
admet-505	605	6	.	.	PUNCT
admet-505	606	1	there	there	ADV
admet-505	606	2	,	,	PUNCT
admet-505	606	3	the	the	DET
admet-505	606	4	linear	linear	ADJ
admet-505	606	5	increase	increase	NOUN
admet-505	606	6	in	in	ADP
admet-505	606	7	solubility	solubility	NOUN
admet-505	606	8	with	with	ADP
admet-505	606	9	increasing	increase	VERB
admet-505	606	10	sds	sds	PROPN
admet-505	606	11	is	be	AUX
admet-505	606	12	compatible	compatible	ADJ
admet-505	606	13	with	with	ADP
admet-505	606	14	four	four	NUM
admet-505	606	15	protonated	protonated	ADJ
admet-505	606	16	drugs	drug	NOUN
admet-505	606	17	bound	bind	VERB
admet-505	606	18	per	per	ADP
admet-505	606	19	micelle	micelle	NOUN
admet-505	606	20	alex	alex	PROPN
admet-505	606	21	avdeef	avdeef	PROPN
admet-505	606	22	admet	admet	PROPN
admet-505	606	23	&	&	CCONJ
admet-505	606	24	dmpk	dmpk	PROPN
admet-505	606	25	6(2	6(2	NUM
admet-505	606	26	)	)	PUNCT
admet-505	606	27	(	(	PUNCT
admet-505	606	28	2018	2018	NUM
admet-505	606	29	)	)	PUNCT
admet-505	606	30	105	105	NUM
admet-505	606	31	-	-	SYM
admet-505	606	32	139	139	NUM
admet-505	606	33	126	126	NUM
admet-505	606	34	aggregate	aggregate	NOUN
admet-505	606	35	.	.	PUNCT
admet-505	607	1	eq	eq	ADJ
admet-505	607	2	.	.	PUNCT
admet-505	608	1	(	(	PUNCT
admet-505	608	2	13	13	NUM
admet-505	608	3	)	)	PUNCT
admet-505	608	4	can	can	AUX
admet-505	608	5	not	not	PART
admet-505	608	6	be	be	AUX
admet-505	608	7	used	use	VERB
admet-505	608	8	,	,	PUNCT
admet-505	608	9	as	as	SCONJ
admet-505	608	10	noted	note	VERB
admet-505	608	11	earlier	early	ADV
admet-505	608	12	.	.	PUNCT
admet-505	609	1	the	the	DET
admet-505	609	2	red	red	NOUN
admet-505	609	3	dashed	dash	VERB
admet-505	609	4	(	(	PUNCT
admet-505	609	5	38	38	NUM
admet-505	609	6	mm	mm	NOUN
admet-505	609	7	)	)	PUNCT
admet-505	609	8	best	well	ADV
admet-505	609	9	-	-	PUNCT
admet-505	609	10	fit	fit	ADJ
admet-505	609	11	curve	curve	NOUN
admet-505	609	12	matches	match	VERB
admet-505	609	13	the	the	DET
admet-505	609	14	data	datum	NOUN
admet-505	609	15	at	at	ADP
admet-505	609	16	the	the	DET
admet-505	609	17	two	two	NUM
admet-505	609	18	lowest	low	ADJ
admet-505	609	19	and	and	CCONJ
admet-505	609	20	the	the	DET
admet-505	609	21	four	four	NUM
admet-505	609	22	highest	high	ADJ
admet-505	609	23	[	[	NOUN
admet-505	609	24	sds]tot	sds]tot	NOUN
admet-505	609	25	points	point	NOUN
admet-505	609	26	(	(	PUNCT
admet-505	609	27	squares	square	NOUN
admet-505	609	28	)	)	PUNCT
admet-505	609	29	,	,	PUNCT
admet-505	609	30	but	but	CCONJ
admet-505	609	31	not	not	PART
admet-505	609	32	the	the	DET
admet-505	609	33	three	three	NUM
admet-505	609	34	points	point	NOUN
admet-505	609	35	in	in	ADP
admet-505	609	36	the	the	DET
admet-505	609	37	middle	middle	NOUN
admet-505	609	38	.	.	PUNCT
admet-505	610	1	the	the	DET
admet-505	610	2	refinement	refinement	NOUN
admet-505	610	3	of	of	ADP
admet-505	610	4	equilibrium	equilibrium	NOUN
admet-505	610	5	constants	constant	NOUN
admet-505	610	6	(	(	PUNCT
admet-505	610	7	at	at	ADP
admet-505	610	8	38	38	NUM
admet-505	610	9	mm	mm	NOUN
admet-505	610	10	)	)	PUNCT
admet-505	610	11	was	be	AUX
admet-505	610	12	carried	carry	VERB
admet-505	610	13	out	out	ADP
admet-505	610	14	by	by	ADP
admet-505	610	15	assigning	assign	VERB
admet-505	610	16	zero	zero	NUM
admet-505	610	17	weights	weight	NOUN
admet-505	610	18	to	to	ADP
admet-505	610	19	the	the	DET
admet-505	610	20	latter	latter	ADJ
admet-505	610	21	three	three	NUM
admet-505	610	22	points	point	NOUN
admet-505	610	23	.	.	PUNCT
admet-505	611	1	the	the	DET
admet-505	611	2	red	red	ADJ
admet-505	611	3	solid	solid	ADJ
admet-505	611	4	(	(	PUNCT
admet-505	611	5	15	15	NUM
admet-505	611	6	mm	mm	NOUN
admet-505	611	7	)	)	PUNCT
admet-505	611	8	curve	curve	NOUN
admet-505	611	9	is	be	AUX
admet-505	611	10	the	the	DET
admet-505	611	11	best	good	ADJ
admet-505	611	12	fit	fit	ADJ
admet-505	611	13	to	to	ADP
admet-505	611	14	all	all	DET
admet-505	611	15	the	the	DET
admet-505	611	16	data	datum	NOUN
admet-505	611	17	,	,	PUNCT
admet-505	611	18	except	except	SCONJ
admet-505	611	19	that	that	PRON
admet-505	611	20	of	of	ADP
admet-505	611	21	the	the	DET
admet-505	611	22	first	first	ADJ
admet-505	611	23	two	two	NUM
admet-505	611	24	points	point	NOUN
admet-505	611	25	.	.	PUNCT
admet-505	612	1	figure	figure	NOUN
admet-505	612	2	9	9	NUM
admet-505	612	3	.	.	PUNCT
admet-505	612	4	mass	mass	ADJ
admet-505	612	5	action	action	NOUN
admet-505	612	6	analysis	analysis	NOUN
admet-505	612	7	of	of	ADP
admet-505	612	8	the	the	DET
admet-505	612	9	solubilization	solubilization	NOUN
admet-505	612	10	of	of	ADP
admet-505	612	11	pg-300995	pg-300995	NOUN
admet-505	612	12	at	at	ADP
admet-505	612	13	ph	ph	PROPN
admet-505	612	14	7	7	NUM
admet-505	612	15	,	,	PUNCT
admet-505	612	16	where	where	SCONJ
admet-505	612	17	the	the	DET
admet-505	612	18	drug	drug	NOUN
admet-505	612	19	is	be	AUX
admet-505	612	20	uncharged	uncharged	ADJ
admet-505	612	21	.	.	PUNCT
admet-505	613	1	(	(	PUNCT
admet-505	613	2	a	a	X
admet-505	613	3	)	)	PUNCT
admet-505	613	4	total	total	ADJ
admet-505	613	5	drug	drug	NOUN
admet-505	613	6	solubility	solubility	NOUN
admet-505	613	7	vs.	vs.	X
admet-505	613	8	{	{	PUNCT
admet-505	613	9	sds]tot	sds]tot	NOUN
admet-505	613	10	,	,	PUNCT
admet-505	613	11	(	(	PUNCT
admet-505	613	12	b	b	X
admet-505	613	13	)	)	PUNCT
admet-505	613	14	speciation	speciation	NOUN
admet-505	613	15	profile	profile	NOUN
admet-505	613	16	,	,	PUNCT
admet-505	613	17	(	(	PUNCT
admet-505	613	18	c	c	X
admet-505	613	19	)	)	PUNCT
admet-505	613	20	mass	mass	ADJ
admet-505	613	21	action	action	NOUN
admet-505	613	22	model	model	NOUN
admet-505	613	23	summary	summary	NOUN
admet-505	613	24	(	(	PUNCT
admet-505	613	25	b	b	NOUN
admet-505	613	26	=	=	SYM
admet-505	613	27	pg-300995	pg-300995	PROPN
admet-505	613	28	)	)	PUNCT
admet-505	613	29	.	.	PUNCT
admet-505	614	1	the	the	DET
admet-505	614	2	mass	mass	PROPN
admet-505	614	3	action	action	NOUN
admet-505	614	4	model	model	NOUN
admet-505	614	5	consisted	consist	VERB
admet-505	614	6	of	of	ADP
admet-505	614	7	three	three	NUM
admet-505	614	8	homogeneous	homogeneous	ADJ
admet-505	614	9	and	and	CCONJ
admet-505	614	10	three	three	NUM
admet-505	614	11	heterogeneous	heterogeneous	ADJ
admet-505	614	12	equilibria	equilibrium	NOUN
admet-505	614	13	,	,	PUNCT
admet-505	614	14	summarized	summarize	VERB
admet-505	614	15	in	in	ADP
admet-505	614	16	the	the	DET
admet-505	614	17	box	box	NOUN
admet-505	614	18	in	in	ADP
admet-505	614	19	figure	figure	NOUN
admet-505	614	20	10c	10c	NOUN
admet-505	614	21	.	.	PUNCT
admet-505	615	1	for	for	ADP
admet-505	615	2	the	the	DET
admet-505	615	3	entire	entire	ADJ
admet-505	615	4	range	range	NOUN
admet-505	615	5	of	of	ADP
admet-505	615	6	sds	sds	PROPN
admet-505	615	7	values	value	NOUN
admet-505	615	8	,	,	PUNCT
admet-505	615	9	the	the	DET
admet-505	615	10	precipitated	precipitate	VERB
admet-505	615	11	form	form	NOUN
admet-505	615	12	of	of	ADP
admet-505	615	13	the	the	DET
admet-505	615	14	drug	drug	NOUN
admet-505	615	15	is	be	AUX
admet-505	615	16	the	the	DET
admet-505	615	17	estolate	estolate	ADJ
admet-505	615	18	salt	salt	NOUN
admet-505	615	19	.	.	PUNCT
admet-505	616	1	the	the	DET
admet-505	616	2	hydrochloride	hydrochloride	NOUN
admet-505	616	3	salt	salt	NOUN
admet-505	616	4	was	be	AUX
admet-505	616	5	included	include	VERB
admet-505	616	6	in	in	ADP
admet-505	616	7	the	the	DET
admet-505	616	8	analysis	analysis	NOUN
admet-505	616	9	,	,	PUNCT
admet-505	616	10	but	but	CCONJ
admet-505	616	11	the	the	DET
admet-505	616	12	data	datum	NOUN
admet-505	616	13	did	do	AUX
admet-505	616	14	not	not	PART
admet-505	616	15	support	support	VERB
admet-505	616	16	its	its	PRON
admet-505	616	17	role	role	NOUN
admet-505	616	18	in	in	ADP
admet-505	616	19	this	this	DET
admet-505	616	20	complicated	complicate	VERB
admet-505	616	21	solubilization	solubilization	NOUN
admet-505	616	22	system	system	NOUN
admet-505	616	23	.	.	PUNCT
admet-505	617	1	figure	figure	NOUN
admet-505	617	2	10b	10b	NOUN
admet-505	617	3	displays	display	VERB
admet-505	617	4	the	the	DET
admet-505	617	5	underlying	underlie	VERB
admet-505	617	6	reactant	reactant	NOUN
admet-505	617	7	and	and	CCONJ
admet-505	617	8	complex	complex	ADJ
admet-505	617	9	species	specie	NOUN
admet-505	617	10	formed	form	VERB
admet-505	617	11	with	with	ADP
admet-505	617	12	increasing	increase	VERB
admet-505	617	13	sds	sds	NOUN
admet-505	617	14	for	for	ADP
admet-505	617	15	15	15	NUM
admet-505	617	16	mm	mm	PROPN
admet-505	617	17	total	total	ADJ
admet-505	617	18	added	add	VERB
admet-505	617	19	drug	drug	NOUN
admet-505	617	20	.	.	PUNCT
admet-505	618	1	the	the	DET
admet-505	618	2	curves	curve	NOUN
admet-505	618	3	for	for	ADP
admet-505	618	4	some	some	PRON
admet-505	618	5	of	of	ADP
admet-505	618	6	the	the	DET
admet-505	618	7	species	specie	NOUN
admet-505	618	8	were	be	AUX
admet-505	618	9	scaled	scale	VERB
admet-505	618	10	in	in	ADP
admet-505	618	11	order	order	NOUN
admet-505	618	12	to	to	PART
admet-505	618	13	appear	appear	VERB
admet-505	618	14	in	in	ADP
admet-505	618	15	the	the	DET
admet-505	618	16	same	same	ADJ
admet-505	618	17	view	view	NOUN
admet-505	618	18	.	.	PUNCT
admet-505	619	1	the	the	DET
admet-505	619	2	cmc	cmc	PROPN
admet-505	619	3	break	break	NOUN
admet-505	619	4	in	in	ADP
admet-505	619	5	the	the	DET
admet-505	619	6	curves	curve	NOUN
admet-505	619	7	occurs	occur	VERB
admet-505	619	8	at	at	ADP
admet-505	619	9	17	17	NUM
admet-505	619	10	mm	mm	NOUN
admet-505	619	11	,	,	PUNCT
admet-505	619	12	corresponding	correspond	VERB
admet-505	619	13	to	to	ADP
admet-505	619	14	an	an	DET
admet-505	619	15	unusually	unusually	ADV
admet-505	619	16	elevated	elevated	ADJ
admet-505	619	17	value	value	NOUN
admet-505	619	18	,	,	PUNCT
admet-505	619	19	suggesting	suggest	VERB
admet-505	619	20	a	a	DET
admet-505	619	21	weakened	weaken	VERB
admet-505	619	22	micellar	micellar	NOUN
admet-505	619	23	structure	structure	NOUN
admet-505	619	24	compared	compare	VERB
admet-505	619	25	to	to	ADP
admet-505	619	26	drug	drug	NOUN
admet-505	619	27	-	-	PUNCT
admet-505	619	28	free	free	ADJ
admet-505	619	29	conditions	condition	NOUN
admet-505	619	30	.	.	PUNCT
admet-505	620	1	stabilizing	stabilize	VERB
admet-505	620	2	cocrystal	cocrystal	ADJ
admet-505	620	3	suspension	suspension	NOUN
admet-505	620	4	with	with	ADP
admet-505	620	5	sds	sds	PROPN
admet-505	620	6	carbamazepine	carbamazepine	NOUN
admet-505	620	7	:	:	PUNCT
admet-505	620	8	saccharin	saccharin	NOUN
admet-505	620	9	1:1	1:1	NUM
admet-505	620	10	cocrystal	cocrystal	ADJ
admet-505	620	11	–	–	PUNCT
admet-505	620	12	experimental	experimental	ADJ
admet-505	620	13	data	datum	NOUN
admet-505	620	14	from	from	ADP
admet-505	620	15	cao	cao	PROPN
admet-505	620	16	et	et	PROPN
admet-505	620	17	al	al	PROPN
admet-505	620	18	.	.	PUNCT
admet-505	621	1	[	[	X
admet-505	621	2	9	9	X
admet-505	621	3	]	]	PUNCT
admet-505	621	4	there	there	PRON
admet-505	621	5	are	be	VERB
admet-505	621	6	very	very	ADV
admet-505	621	7	few	few	ADJ
admet-505	621	8	published	publish	VERB
admet-505	621	9	examples	example	NOUN
admet-505	621	10	[	[	X
admet-505	621	11	9	9	NUM
admet-505	621	12	,	,	PUNCT
admet-505	621	13	33	33	NUM
admet-505	621	14	]	]	PUNCT
admet-505	621	15	of	of	ADP
admet-505	621	16	eutectic	eutectic	ADJ
admet-505	621	17	data	datum	NOUN
admet-505	621	18	for	for	ADP
admet-505	621	19	both	both	CCONJ
admet-505	621	20	the	the	DET
admet-505	621	21	api	api	NOUN
admet-505	621	22	and	and	CCONJ
admet-505	621	23	the	the	DET
admet-505	621	24	coformer	coformer	NOUN
admet-505	621	25	in	in	ADP
admet-505	621	26	assays	assay	NOUN
admet-505	621	27	where	where	SCONJ
admet-505	621	28	surfactant	surfactant	NOUN
admet-505	621	29	had	have	AUX
admet-505	621	30	been	be	AUX
admet-505	621	31	added	add	VERB
admet-505	621	32	.	.	PUNCT
admet-505	622	1	cao	cao	PROPN
admet-505	622	2	et	et	PROPN
admet-505	622	3	al	al	PROPN
admet-505	622	4	.	.	PUNCT
admet-505	623	1	[	[	X
admet-505	623	2	9	9	NUM
admet-505	623	3	]	]	PUNCT
admet-505	623	4	published	publish	VERB
admet-505	623	5	an	an	DET
admet-505	623	6	in	in	ADP
admet-505	623	7	-	-	PUNCT
admet-505	623	8	depth	depth	NOUN
admet-505	623	9	mechanistic	mechanistic	ADJ
admet-505	623	10	dissolution	dissolution	NOUN
admet-505	623	11	study	study	NOUN
admet-505	623	12	of	of	ADP
admet-505	623	13	the	the	DET
admet-505	623	14	carbamazepine	carbamazepine	NOUN
admet-505	623	15	:	:	PUNCT
admet-505	623	16	saccharin	saccharin	NOUN
admet-505	623	17	1:1	1:1	NUM
admet-505	623	18	cocrystal	cocrystal	ADJ
admet-505	623	19	system	system	NOUN
admet-505	623	20	,	,	PUNCT
admet-505	623	21	which	which	PRON
admet-505	623	22	included	include	VERB
admet-505	623	23	such	such	ADJ
admet-505	623	24	eutectic	eutectic	ADJ
admet-505	623	25	data	datum	NOUN
admet-505	623	26	for	for	ADP
admet-505	623	27	both	both	DET
admet-505	623	28	carbamazepine	carbamazepine	NOUN
admet-505	623	29	and	and	CCONJ
admet-505	623	30	admet	admet	PROPN
admet-505	623	31	&	&	CCONJ
admet-505	623	32	dmpk	dmpk	PROPN
admet-505	623	33	6(2	6(2	NUM
admet-505	623	34	)	)	PUNCT
admet-505	623	35	(	(	PUNCT
admet-505	623	36	2018	2018	NUM
admet-505	623	37	)	)	PUNCT
admet-505	623	38	105	105	NUM
admet-505	623	39	-	-	SYM
admet-505	623	40	139	139	NUM
admet-505	623	41	cocrystal	cocrystal	ADJ
admet-505	623	42	solubility	solubility	NOUN
admet-505	623	43	-	-	PUNCT
admet-505	623	44	ph	ph	VERB
admet-505	623	45	,	,	PUNCT
admet-505	623	46	drug	drug	NOUN
admet-505	623	47	solubilization	solubilization	NOUN
admet-505	623	48	capacity	capacity	NOUN
admet-505	623	49	of	of	ADP
admet-505	623	50	sds	sds	PROPN
admet-505	623	51	,	,	PUNCT
admet-505	623	52	mass	mass	ADJ
admet-505	623	53	action	action	NOUN
admet-505	623	54	model	model	NOUN
admet-505	623	55	doi	doi	PROPN
admet-505	623	56	:	:	PUNCT
admet-505	623	57	10.5599	10.5599	NUM
admet-505	623	58	/	/	SYM
admet-505	623	59	admet.505	admet.505	PROPN
admet-505	623	60	127	127	NUM
admet-505	623	61	saccharin	saccharin	NOUN
admet-505	623	62	at	at	ADP
admet-505	623	63	ph	ph	PROPN
admet-505	623	64	1	1	NUM
admet-505	623	65	in	in	ADP
admet-505	623	66	the	the	DET
admet-505	623	67	presence	presence	NOUN
admet-505	623	68	of	of	ADP
admet-505	623	69	22	22	NUM
admet-505	623	70	,	,	PUNCT
admet-505	623	71	44	44	NUM
admet-505	623	72	,	,	PUNCT
admet-505	623	73	250	250	NUM
admet-505	623	74	,	,	PUNCT
admet-505	623	75	and	and	CCONJ
admet-505	623	76	400	400	NUM
admet-505	623	77	mm	mm	PROPN
admet-505	623	78	sds	sds	PROPN
admet-505	623	79	.	.	PUNCT
admet-505	624	1	the	the	DET
admet-505	624	2	cc	cc	PROPN
admet-505	624	3	system	system	NOUN
admet-505	624	4	had	have	AUX
admet-505	624	5	been	be	AUX
admet-505	624	6	thoroughly	thoroughly	ADV
admet-505	624	7	studied	study	VERB
admet-505	624	8	in	in	ADP
admet-505	624	9	surfactant	surfactant	NOUN
admet-505	624	10	-	-	PUNCT
admet-505	624	11	free	free	ADJ
admet-505	624	12	media	medium	NOUN
admet-505	624	13	[	[	X
admet-505	624	14	62	62	NUM
admet-505	624	15	-	-	SYM
admet-505	624	16	64	64	NUM
admet-505	624	17	]	]	PUNCT
admet-505	624	18	,	,	PUNCT
admet-505	624	19	and	and	CCONJ
admet-505	624	20	had	have	AUX
admet-505	624	21	been	be	AUX
admet-505	624	22	subjected	subject	VERB
admet-505	624	23	to	to	ADP
admet-505	624	24	pdisol	pdisol	ADJ
admet-505	624	25	-	-	PUNCT
admet-505	624	26	x	x	NOUN
admet-505	624	27	analysis	analysis	NOUN
admet-505	624	28	[	[	X
admet-505	624	29	16	16	NUM
admet-505	624	30	,	,	PUNCT
admet-505	624	31	17	17	NUM
admet-505	624	32	]	]	PUNCT
admet-505	624	33	.	.	PUNCT
admet-505	625	1	figure	figure	NOUN
admet-505	625	2	10	10	NUM
admet-505	625	3	.	.	PUNCT
admet-505	626	1	mass	mass	ADJ
admet-505	626	2	action	action	NOUN
admet-505	626	3	analysis	analysis	NOUN
admet-505	626	4	of	of	ADP
admet-505	626	5	the	the	DET
admet-505	626	6	solubilization	solubilization	NOUN
admet-505	626	7	of	of	ADP
admet-505	626	8	pg-300995	pg-300995	NOUN
admet-505	626	9	at	at	ADP
admet-505	626	10	ph	ph	PROPN
admet-505	626	11	1	1	NUM
admet-505	626	12	,	,	PUNCT
admet-505	626	13	where	where	SCONJ
admet-505	626	14	the	the	DET
admet-505	626	15	drug	drug	NOUN
admet-505	626	16	is	be	AUX
admet-505	626	17	positively	positively	ADV
admet-505	626	18	charged	charge	VERB
admet-505	626	19	.	.	PUNCT
admet-505	627	1	(	(	PUNCT
admet-505	627	2	a	a	X
admet-505	627	3	)	)	PUNCT
admet-505	627	4	total	total	ADJ
admet-505	627	5	drug	drug	NOUN
admet-505	627	6	solubility	solubility	NOUN
admet-505	627	7	vs.	vs.	ADP
admet-505	627	8	[	[	X
admet-505	627	9	sds]tot	sds]tot	NOUN
admet-505	627	10	at	at	ADP
admet-505	627	11	three	three	NUM
admet-505	627	12	levels	level	NOUN
admet-505	627	13	of	of	ADP
admet-505	627	14	total	total	ADJ
admet-505	627	15	drug	drug	NOUN
admet-505	627	16	concentration	concentration	NOUN
admet-505	627	17	,	,	PUNCT
admet-505	627	18	(	(	PUNCT
admet-505	627	19	b	b	X
admet-505	627	20	)	)	PUNCT
admet-505	627	21	speciation	speciation	NOUN
admet-505	627	22	profile	profile	NOUN
admet-505	627	23	at	at	ADP
admet-505	627	24	15	15	NUM
admet-505	627	25	mm	mm	NOUN
admet-505	627	26	total	total	ADJ
admet-505	627	27	drug	drug	NOUN
admet-505	627	28	concentration	concentration	NOUN
admet-505	627	29	,	,	PUNCT
admet-505	627	30	(	(	PUNCT
admet-505	627	31	c	c	X
admet-505	627	32	)	)	PUNCT
admet-505	627	33	mass	mass	ADJ
admet-505	627	34	action	action	NOUN
admet-505	627	35	model	model	NOUN
admet-505	627	36	summary	summary	NOUN
admet-505	627	37	(	(	PUNCT
admet-505	627	38	b	b	NOUN
admet-505	627	39	=	=	SYM
admet-505	627	40	pg-300995	pg-300995	PROPN
admet-505	627	41	)	)	PUNCT
admet-505	627	42	.	.	PUNCT
admet-505	628	1	the	the	DET
admet-505	628	2	non	non	ADJ
admet-505	628	3	-	-	ADJ
admet-505	628	4	cc	cc	ADJ
admet-505	628	5	carbamazepine	carbamazepine	NOUN
admet-505	628	6	solubility	solubility	PROPN
admet-505	628	7	-	-	PUNCT
admet-505	628	8	sds	sds	PROPN
admet-505	628	9	data	datum	NOUN
admet-505	628	10	at	at	ADP
admet-505	628	11	25	25	NUM
admet-505	628	12	°	°	NOUN
admet-505	628	13	c	c	NOUN
admet-505	628	14	[	[	X
admet-505	628	15	6	6	NUM
admet-505	628	16	]	]	PUNCT
admet-505	628	17	in	in	ADP
admet-505	628	18	figure	figure	NOUN
admet-505	628	19	2d	2d	NUM
admet-505	628	20	were	be	AUX
admet-505	628	21	subjected	subject	VERB
admet-505	628	22	to	to	ADP
admet-505	628	23	mass	mass	ADJ
admet-505	628	24	action	action	NOUN
admet-505	628	25	analysis	analysis	NOUN
admet-505	628	26	to	to	PART
admet-505	628	27	determine	determine	VERB
admet-505	628	28	the	the	DET
admet-505	628	29	best	good	ADJ
admet-505	628	30	-	-	PUNCT
admet-505	628	31	fit	fit	ADJ
admet-505	628	32	drug	drug	NOUN
admet-505	628	33	-	-	PUNCT
admet-505	628	34	micelle	micelle	NOUN
admet-505	628	35	binding	bind	VERB
admet-505	628	36	constant	constant	ADJ
admet-505	628	37	,	,	PUNCT
admet-505	628	38	and	and	CCONJ
admet-505	628	39	to	to	PART
admet-505	628	40	attempt	attempt	VERB
admet-505	628	41	to	to	PART
admet-505	628	42	predict	predict	VERB
admet-505	628	43	the	the	DET
admet-505	628	44	curvature	curvature	NOUN
admet-505	628	45	in	in	ADP
admet-505	628	46	the	the	DET
admet-505	628	47	post	post	ADJ
admet-505	628	48	-	-	ADJ
admet-505	628	49	cmc	cmc	ADJ
admet-505	628	50	plots	plot	NOUN
admet-505	628	51	.	.	PUNCT
admet-505	629	1	it	it	PRON
admet-505	629	2	was	be	AUX
admet-505	629	3	assumed	assume	VERB
admet-505	629	4	that	that	SCONJ
admet-505	629	5	22	22	NUM
admet-505	629	6	carbamazepine	carbamazepine	NOUN
admet-505	629	7	molecules	molecule	NOUN
admet-505	629	8	bind	bind	VERB
admet-505	629	9	to	to	ADP
admet-505	629	10	one	one	NUM
admet-505	629	11	sds	sds	NOUN
admet-505	629	12	micelle	micelle	NOUN
admet-505	629	13	aggregate	aggregate	VERB
admet-505	629	14	(	(	PUNCT
admet-505	629	15	cf	cf	NOUN
admet-505	629	16	.	.	PUNCT
admet-505	629	17	,	,	PUNCT
admet-505	629	18	table	table	NOUN
admet-505	629	19	1	1	NUM
admet-505	629	20	)	)	PUNCT
admet-505	629	21	.	.	PUNCT
admet-505	630	1	at	at	ADV
admet-505	630	2	least	least	ADV
admet-505	630	3	three	three	NUM
admet-505	630	4	constants	constant	NOUN
admet-505	630	5	were	be	AUX
admet-505	630	6	needed	need	VERB
admet-505	630	7	to	to	PART
admet-505	630	8	explain	explain	VERB
admet-505	630	9	the	the	DET
admet-505	630	10	data	datum	NOUN
admet-505	630	11	pattern	pattern	NOUN
admet-505	630	12	in	in	ADP
admet-505	630	13	figure	figure	NOUN
admet-505	630	14	2d	2d	NOUN
admet-505	630	15	:	:	PUNCT
admet-505	630	16	log	log	VERB
admet-505	630	17	ksds	ksds	NOUN
admet-505	631	1	=	=	NOUN
admet-505	632	1	230.6	230.6	NUM
admet-505	632	2	,	,	PUNCT
admet-505	632	3	log	log	NOUN
admet-505	632	4	k22	k22	NOUN
admet-505	632	5	=	=	SYM
admet-505	632	6	74.0	74.0	NUM
admet-505	632	7	,	,	PUNCT
admet-505	632	8	log	log	NOUN
admet-505	632	9	s0	s0	NOUN
admet-505	632	10	=	=	PUNCT
admet-505	632	11	-3.33	-3.33	NOUN
admet-505	632	12	,	,	PUNCT
admet-505	632	13	gof	gof	NOUN
admet-505	632	14	=	=	PROPN
admet-505	632	15	0.50	0.50	NUM
admet-505	632	16	,	,	PUNCT
admet-505	632	17	n	n	PROPN
admet-505	632	18	=	=	SYM
admet-505	632	19	37	37	NUM
admet-505	632	20	.	.	PUNCT
admet-505	633	1	there	there	PRON
admet-505	633	2	was	be	VERB
admet-505	633	3	a	a	DET
admet-505	633	4	tiny	tiny	ADJ
admet-505	633	5	bend	bend	NOUN
admet-505	633	6	in	in	ADP
admet-505	633	7	the	the	DET
admet-505	633	8	calculated	calculate	VERB
admet-505	633	9	mass	mass	ADJ
admet-505	633	10	action	action	NOUN
admet-505	633	11	post	post	ADJ
admet-505	633	12	-	-	ADJ
admet-505	633	13	cmc	cmc	ADJ
admet-505	633	14	curve	curve	NOUN
admet-505	633	15	(	(	PUNCT
admet-505	633	16	due	due	ADP
admet-505	633	17	to	to	ADP
admet-505	633	18	ionic	ionic	ADJ
admet-505	633	19	strength	strength	NOUN
admet-505	633	20	effects	effect	NOUN
admet-505	633	21	)	)	PUNCT
admet-505	633	22	,	,	PUNCT
admet-505	633	23	but	but	CCONJ
admet-505	633	24	not	not	PART
admet-505	633	25	fully	fully	ADV
admet-505	633	26	matching	match	VERB
admet-505	633	27	the	the	DET
admet-505	633	28	extent	extent	NOUN
admet-505	633	29	of	of	ADP
admet-505	633	30	the	the	DET
admet-505	633	31	curvature	curvature	NOUN
admet-505	633	32	observed	observe	VERB
admet-505	633	33	for	for	ADP
admet-505	633	34	[	[	X
admet-505	633	35	sds]tot	sds]tot	NOUN
admet-505	633	36	>	>	X
admet-505	633	37	70	70	NUM
admet-505	633	38	mm	mm	NOUN
admet-505	633	39	,	,	PUNCT
admet-505	633	40	where	where	SCONJ
admet-505	633	41	solubilization	solubilization	NOUN
admet-505	633	42	capacity	capacity	NOUN
admet-505	633	43	notably	notably	ADV
admet-505	633	44	decreased	decrease	VERB
admet-505	633	45	.	.	PUNCT
admet-505	634	1	this	this	PRON
admet-505	634	2	was	be	AUX
admet-505	634	3	expected	expect	VERB
admet-505	634	4	to	to	PART
admet-505	634	5	complicate	complicate	VERB
admet-505	634	6	the	the	DET
admet-505	634	7	quantitative	quantitative	ADJ
admet-505	634	8	assessment	assessment	NOUN
admet-505	634	9	of	of	ADP
admet-505	634	10	the	the	DET
admet-505	634	11	eutectic	eutectic	ADJ
admet-505	634	12	data	datum	NOUN
admet-505	634	13	of	of	ADP
admet-505	634	14	cao	cao	PROPN
admet-505	634	15	et	et	PROPN
admet-505	634	16	al	al	PROPN
admet-505	634	17	.	.	PUNCT
admet-505	635	1	[	[	X
admet-505	635	2	9	9	NUM
admet-505	635	3	]	]	PUNCT
admet-505	635	4	,	,	PUNCT
admet-505	635	5	who	who	PRON
admet-505	635	6	considered	consider	VERB
admet-505	635	7	[	[	PUNCT
admet-505	635	8	sds]tot	sds]tot	NOUN
admet-505	635	9	as	as	ADV
admet-505	635	10	high	high	ADJ
admet-505	635	11	as	as	ADP
admet-505	635	12	400	400	NUM
admet-505	635	13	mm	mm	NOUN
admet-505	635	14	.	.	PUNCT
admet-505	636	1	from	from	ADP
admet-505	636	2	the	the	DET
admet-505	636	3	non	non	ADJ
admet-505	636	4	-	-	ADJ
admet-505	636	5	sds	sds	ADJ
admet-505	636	6	carbamazepine	carbamazepine	NOUN
admet-505	636	7	:	:	PUNCT
admet-505	636	8	saccharin	saccharin	NOUN
admet-505	636	9	1:1	1:1	NUM
admet-505	637	1	cc	cc	NOUN
admet-505	637	2	solubility	solubility	NOUN
admet-505	637	3	-	-	PUNCT
admet-505	637	4	ph	ph	ADJ
admet-505	637	5	data	datum	NOUN
admet-505	637	6	,	,	PUNCT
admet-505	637	7	the	the	DET
admet-505	637	8	mean	mean	NOUN
admet-505	637	9	of	of	ADP
admet-505	637	10	the	the	DET
admet-505	637	11	equilibrium	equilibrium	NOUN
admet-505	637	12	constants	constant	NOUN
admet-505	637	13	reported	report	VERB
admet-505	637	14	previously	previously	ADV
admet-505	637	15	[	[	X
admet-505	637	16	17	17	NUM
admet-505	637	17	,	,	PUNCT
admet-505	637	18	63	63	NUM
admet-505	637	19	,	,	PUNCT
admet-505	637	20	64	64	NUM
admet-505	637	21	]	]	PUNCT
admet-505	637	22	are	be	AUX
admet-505	637	23	pka	pka	PROPN
admet-505	637	24	cof	cof	PROPN
admet-505	637	25	=	=	PROPN
admet-505	637	26	1.31	1.31	NUM
admet-505	637	27	,	,	PUNCT
admet-505	637	28	log	log	PROPN
admet-505	637	29	ksp	ksp	PROPN
admet-505	637	30	=	=	PROPN
admet-505	637	31	-6.01	-6.01	PROPN
admet-505	637	32	and	and	CCONJ
admet-505	637	33	log	log	VERB
admet-505	637	34	s0	s0	NOUN
admet-505	637	35	=	=	PUNCT
admet-505	637	36	-3.26	-3.26	ADJ
admet-505	637	37	.	.	PUNCT
admet-505	638	1	one	one	NUM
admet-505	638	2	additional	additional	ADJ
admet-505	638	3	constant	constant	ADJ
admet-505	638	4	was	be	AUX
admet-505	638	5	needed	need	VERB
admet-505	638	6	,	,	PUNCT
admet-505	638	7	kn	kn	PROPN
admet-505	638	8	cof	cof	PROPN
admet-505	638	9	,	,	PUNCT
admet-505	638	10	before	before	ADP
admet-505	638	11	the	the	DET
admet-505	638	12	cao	cao	PROPN
admet-505	638	13	et	et	PROPN
admet-505	638	14	al	al	PROPN
admet-505	638	15	.	.	PROPN
admet-505	639	1	eutectic	eutectic	PROPN
admet-505	639	2	solubility	solubility	NOUN
admet-505	639	3	data	datum	NOUN
admet-505	639	4	could	could	AUX
admet-505	639	5	be	be	AUX
admet-505	639	6	processes	process	NOUN
admet-505	639	7	by	by	ADP
admet-505	639	8	pdisol	pdisol	NOUN
admet-505	639	9	-	-	PUNCT
admet-505	639	10	x.	x.	NOUN
admet-505	639	11	the	the	DET
admet-505	639	12	formula	formula	NOUN
admet-505	639	13	for	for	ADP
admet-505	639	14	acids	acid	NOUN
admet-505	639	15	in	in	ADP
admet-505	639	16	table	table	NOUN
admet-505	639	17	2	2	NUM
admet-505	639	18	predicted	predict	VERB
admet-505	639	19	the	the	DET
admet-505	639	20	k	k	PROPN
admet-505	639	21	value	value	NOUN
admet-505	639	22	of	of	ADP
admet-505	639	23	saccharin	saccharin	NOUN
admet-505	639	24	to	to	PART
admet-505	639	25	be	be	AUX
admet-505	639	26	0.516	0.516	NUM
admet-505	639	27	.	.	PUNCT
admet-505	640	1	the	the	DET
admet-505	640	2	product	product	NOUN
admet-505	640	3	of	of	ADP
admet-505	640	4	knagg	knagg	PROPN
admet-505	640	5	suggested	suggest	VERB
admet-505	640	6	that	that	SCONJ
admet-505	640	7	ncof	ncof	NOUN
admet-505	640	8	=	=	SYM
admet-505	640	9	32	32	NUM
admet-505	640	10	(	(	PUNCT
admet-505	640	11	eq	eq	NOUN
admet-505	640	12	.	.	PROPN
admet-505	640	13	14	14	NUM
admet-505	640	14	)	)	PUNCT
admet-505	640	15	.	.	PUNCT
admet-505	641	1	from	from	ADP
admet-505	641	2	eq	eq	ADP
admet-505	641	3	.	.	PUNCT
admet-505	642	1	(	(	PUNCT
admet-505	642	2	13	13	NUM
admet-505	642	3	)	)	PUNCT
admet-505	642	4	,	,	PUNCT
admet-505	642	5	the	the	DET
admet-505	642	6	log	log	NOUN
admet-505	642	7	kn	kn	PROPN
admet-505	642	8	cof	cof	PROPN
admet-505	642	9	was	be	AUX
admet-505	642	10	estimated	estimate	VERB
admet-505	642	11	as	as	ADP
admet-505	642	12	58.9	58.9	NUM
admet-505	642	13	.	.	PUNCT
admet-505	643	1	alex	alex	PROPN
admet-505	643	2	avdeef	avdeef	PROPN
admet-505	643	3	admet	admet	PROPN
admet-505	643	4	&	&	CCONJ
admet-505	643	5	dmpk	dmpk	PROPN
admet-505	643	6	6(2	6(2	NUM
admet-505	643	7	)	)	PUNCT
admet-505	643	8	(	(	PUNCT
admet-505	643	9	2018	2018	NUM
admet-505	643	10	)	)	PUNCT
admet-505	643	11	105	105	NUM
admet-505	643	12	-	-	SYM
admet-505	643	13	139	139	NUM
admet-505	643	14	128	128	NUM
admet-505	643	15	as	as	ADP
admet-505	643	16	the	the	DET
admet-505	643	17	last	last	ADJ
admet-505	643	18	step	step	NOUN
admet-505	643	19	,	,	PUNCT
admet-505	643	20	the	the	DET
admet-505	643	21	eight	eight	NUM
admet-505	643	22	eutectic	eutectic	ADJ
admet-505	643	23	concentration	concentration	NOUN
admet-505	643	24	data	datum	NOUN
admet-505	643	25	(	(	PUNCT
admet-505	643	26	in	in	ADP
admet-505	643	27	22	22	NUM
admet-505	643	28	-	-	SYM
admet-505	643	29	400	400	NUM
admet-505	643	30	mm	mm	NOUN
admet-505	643	31	sds	sds	NOUN
admet-505	644	1	[	[	X
admet-505	644	2	9	9	NUM
admet-505	644	3	]	]	PUNCT
admet-505	644	4	)	)	PUNCT
admet-505	644	5	were	be	AUX
admet-505	644	6	subjected	subject	VERB
admet-505	644	7	to	to	ADP
admet-505	644	8	a	a	DET
admet-505	644	9	series	series	NOUN
admet-505	644	10	of	of	ADP
admet-505	644	11	pdisol	pdisol	ADJ
admet-505	644	12	-	-	PUNCT
admet-505	644	13	x	x	NOUN
admet-505	644	14	analyses	analysis	NOUN
admet-505	644	15	to	to	PART
admet-505	644	16	determine	determine	VERB
admet-505	644	17	the	the	DET
admet-505	644	18	api	api	NOUN
admet-505	644	19	and	and	CCONJ
admet-505	644	20	the	the	DET
admet-505	644	21	coformer	coformer	NOUN
admet-505	644	22	-	-	PUNCT
admet-505	644	23	micelle	micelle	NOUN
admet-505	644	24	binding	bind	VERB
admet-505	644	25	constant	constant	ADJ
admet-505	644	26	,	,	PUNCT
admet-505	644	27	following	follow	VERB
admet-505	644	28	procedures	procedure	NOUN
admet-505	644	29	described	describe	VERB
admet-505	644	30	in	in	ADP
admet-505	644	31	detail	detail	NOUN
admet-505	644	32	elsewhere	elsewhere	ADV
admet-505	644	33	[	[	X
admet-505	644	34	16	16	NUM
admet-505	644	35	,	,	PUNCT
admet-505	644	36	17	17	NUM
admet-505	644	37	]	]	PUNCT
admet-505	644	38	.	.	PUNCT
admet-505	645	1	the	the	DET
admet-505	645	2	mean	mean	ADJ
admet-505	645	3	constants	constant	NOUN
admet-505	645	4	in	in	ADP
admet-505	645	5	the	the	DET
admet-505	645	6	preceding	precede	VERB
admet-505	645	7	paragraph	paragraph	NOUN
admet-505	645	8	were	be	AUX
admet-505	645	9	introduced	introduce	VERB
admet-505	645	10	as	as	ADP
admet-505	645	11	fixed	fix	VERB
admet-505	645	12	parameters	parameter	NOUN
admet-505	645	13	,	,	PUNCT
admet-505	645	14	and	and	CCONJ
admet-505	645	15	were	be	AUX
admet-505	645	16	not	not	PART
admet-505	645	17	refined	refine	VERB
admet-505	645	18	.	.	PUNCT
admet-505	646	1	the	the	DET
admet-505	646	2	estimated	estimate	VERB
admet-505	646	3	kn	kn	PROPN
admet-505	646	4	cof	cof	PROPN
admet-505	646	5	constant	constant	PROPN
admet-505	646	6	indicated	indicate	VERB
admet-505	646	7	that	that	SCONJ
admet-505	646	8	the	the	DET
admet-505	646	9	concentration	concentration	NOUN
admet-505	646	10	of	of	ADP
admet-505	646	11	the	the	DET
admet-505	646	12	saccharin	saccharin	NOUN
admet-505	646	13	-	-	PUNCT
admet-505	646	14	micelle	micelle	NOUN
admet-505	646	15	species	specie	NOUN
admet-505	646	16	maximized	maximize	VERB
admet-505	646	17	at	at	ADP
admet-505	646	18	ph	ph	PROPN
admet-505	646	19	1.7	1.7	NUM
admet-505	646	20	but	but	CCONJ
admet-505	646	21	did	do	AUX
admet-505	646	22	not	not	PART
admet-505	646	23	exceed	exceed	VERB
admet-505	646	24	10	10	NUM
admet-505	646	25	-9	-9	NOUN
admet-505	646	26	m	m	NOUN
admet-505	646	27	;	;	PUNCT
admet-505	646	28	thus	thus	ADV
admet-505	646	29	the	the	DET
admet-505	646	30	constant	constant	ADJ
admet-505	646	31	was	be	AUX
admet-505	646	32	not	not	PART
admet-505	646	33	subjected	subject	VERB
admet-505	646	34	to	to	ADP
admet-505	646	35	refinement	refinement	NOUN
admet-505	646	36	.	.	PUNCT
admet-505	647	1	only	only	ADV
admet-505	647	2	log	log	PROPN
admet-505	647	3	kn	kn	PROPN
admet-505	647	4	was	be	AUX
admet-505	647	5	refined	refine	VERB
admet-505	647	6	.	.	PUNCT
admet-505	648	1	the	the	DET
admet-505	648	2	appendix	appendix	PROPN
admet-505	648	3	defines	define	VERB
admet-505	648	4	the	the	DET
admet-505	648	5	function	function	NOUN
admet-505	648	6	minimized	minimized	ADJ
admet-505	648	7	and	and	CCONJ
admet-505	648	8	the	the	DET
admet-505	648	9	goodness	goodness	NOUN
admet-505	648	10	-	-	PUNCT
admet-505	648	11	of	of	ADP
admet-505	648	12	-	-	PUNCT
admet-505	648	13	fit	fit	ADJ
admet-505	648	14	(	(	PUNCT
admet-505	648	15	gof	gof	ADJ
admet-505	648	16	)	)	PUNCT
admet-505	648	17	statistic	statistic	NOUN
admet-505	648	18	.	.	PUNCT
admet-505	649	1	the	the	DET
admet-505	649	2	analysis	analysis	NOUN
admet-505	649	3	of	of	ADP
admet-505	649	4	the	the	DET
admet-505	649	5	cao	cao	PROPN
admet-505	649	6	et	et	PROPN
admet-505	649	7	al	al	PROPN
admet-505	649	8	.	.	PROPN
admet-505	649	9	data	datum	NOUN
admet-505	649	10	encountered	encounter	VERB
admet-505	649	11	an	an	DET
admet-505	649	12	unexpected	unexpected	ADJ
admet-505	649	13	complication	complication	NOUN
admet-505	649	14	.	.	PUNCT
admet-505	650	1	the	the	DET
admet-505	650	2	refined	refined	ADJ
admet-505	650	3	constant	constant	ADJ
admet-505	650	4	,	,	PUNCT
admet-505	650	5	kn	kn	PROPN
admet-505	650	6	,	,	PUNCT
admet-505	650	7	depended	depend	VERB
admet-505	650	8	critically	critically	ADV
admet-505	650	9	on	on	ADP
admet-505	650	10	the	the	DET
admet-505	650	11	actual	actual	ADJ
admet-505	650	12	weights	weight	NOUN
admet-505	650	13	of	of	ADP
admet-505	650	14	api	api	NOUN
admet-505	650	15	and	and	CCONJ
admet-505	650	16	coformer	coformer	NOUN
admet-505	650	17	added	add	VERB
admet-505	650	18	to	to	ADP
admet-505	650	19	the	the	DET
admet-505	650	20	solutions	solution	NOUN
admet-505	650	21	.	.	PUNCT
admet-505	651	1	the	the	DET
admet-505	651	2	original	original	ADJ
admet-505	651	3	publication	publication	NOUN
admet-505	651	4	stated	state	VERB
admet-505	651	5	the	the	DET
admet-505	651	6	quantities	quantity	NOUN
admet-505	651	7	as	as	ADP
admet-505	651	8	ranges	range	NOUN
admet-505	651	9	:	:	PUNCT
admet-505	651	10	100	100	NUM
admet-505	651	11	-	-	SYM
admet-505	651	12	150	150	NUM
admet-505	651	13	mg	mg	NOUN
admet-505	651	14	cc	cc	NOUN
admet-505	651	15	and	and	CCONJ
admet-505	651	16	50	50	NUM
admet-505	651	17	-	-	SYM
admet-505	651	18	100	100	NUM
admet-505	651	19	mg	mg	NUM
admet-505	651	20	excess	excess	ADJ
admet-505	651	21	carbamazepine	carbamazepine	NOUN
admet-505	651	22	in	in	ADP
admet-505	651	23	3	3	NUM
admet-505	651	24	ml	ml	NOUN
admet-505	651	25	solution	solution	NOUN
admet-505	651	26	.	.	PUNCT
admet-505	652	1	various	various	ADJ
admet-505	652	2	combinations	combination	NOUN
admet-505	652	3	of	of	ADP
admet-505	652	4	weights	weight	NOUN
admet-505	652	5	were	be	AUX
admet-505	652	6	tried	try	VERB
admet-505	652	7	within	within	ADP
admet-505	652	8	/	/	SYM
admet-505	652	9	near	near	ADP
admet-505	652	10	the	the	DET
admet-505	652	11	specified	specify	VERB
admet-505	652	12	ranges	range	NOUN
admet-505	652	13	.	.	PUNCT
admet-505	653	1	the	the	DET
admet-505	653	2	minimum	minimum	ADJ
admet-505	653	3	gof	gof	NOUN
admet-505	653	4	0.79	0.79	NUM
admet-505	653	5	was	be	AUX
admet-505	653	6	found	find	VERB
admet-505	653	7	near	near	ADP
admet-505	653	8	70	70	NUM
admet-505	653	9	mg	mg	NOUN
admet-505	653	10	/	/	SYM
admet-505	653	11	ml	ml	NOUN
admet-505	653	12	cc	cc	ADP
admet-505	653	13	+	+	NOUN
admet-505	653	14	35	35	NUM
admet-505	653	15	mg	mg	NUM
admet-505	653	16	/	/	SYM
admet-505	653	17	ml	ml	NOUN
admet-505	653	18	excess	excess	ADJ
admet-505	653	19	api	api	NOUN
admet-505	653	20	.	.	PUNCT
admet-505	654	1	the	the	DET
admet-505	654	2	refined	refined	ADJ
admet-505	654	3	constant	constant	ADJ
admet-505	654	4	,	,	PUNCT
admet-505	654	5	log	log	NOUN
admet-505	654	6	k22	k22	NOUN
admet-505	654	7	=	=	SYM
admet-505	654	8	84.0	84.0	NUM
admet-505	654	9	,	,	PUNCT
admet-505	654	10	somewhat	somewhat	ADV
admet-505	654	11	higher	high	ADJ
admet-505	654	12	than	than	ADP
admet-505	654	13	the	the	DET
admet-505	654	14	value	value	NOUN
admet-505	654	15	obtained	obtain	VERB
admet-505	654	16	from	from	ADP
admet-505	654	17	non	non	ADJ
admet-505	654	18	-	-	ADJ
admet-505	654	19	cc	cc	ADJ
admet-505	654	20	data	datum	NOUN
admet-505	654	21	.	.	PUNCT
admet-505	655	1	figure	figure	NOUN
admet-505	655	2	11	11	NUM
admet-505	655	3	shows	show	VERB
admet-505	655	4	the	the	DET
admet-505	655	5	eutectic	eutectic	ADJ
admet-505	655	6	curve	curve	NOUN
admet-505	655	7	and	and	CCONJ
admet-505	655	8	speciation	speciation	NOUN
admet-505	655	9	plots	plot	NOUN
admet-505	655	10	for	for	ADP
admet-505	655	11	the	the	DET
admet-505	655	12	cocrystal	cocrystal	ADJ
admet-505	655	13	system	system	NOUN
admet-505	655	14	for	for	ADP
admet-505	655	15	the	the	DET
admet-505	655	16	[	[	NOUN
admet-505	655	17	sds]tot	sds]tot	NOUN
admet-505	655	18	of	of	ADP
admet-505	655	19	0	0	NUM
admet-505	655	20	,	,	PUNCT
admet-505	655	21	22	22	NUM
admet-505	655	22	,	,	PUNCT
admet-505	655	23	44	44	NUM
admet-505	655	24	,	,	PUNCT
admet-505	655	25	250	250	NUM
admet-505	655	26	,	,	PUNCT
admet-505	655	27	and	and	CCONJ
admet-505	655	28	400	400	NUM
admet-505	655	29	mm	mm	NOUN
admet-505	655	30	.	.	PUNCT
admet-505	656	1	it	it	PRON
admet-505	656	2	was	be	AUX
admet-505	656	3	a	a	DET
admet-505	656	4	complicated	complicated	ADJ
admet-505	656	5	calculation	calculation	NOUN
admet-505	656	6	.	.	PUNCT
admet-505	657	1	in	in	ADP
admet-505	657	2	frames	frame	NOUN
admet-505	657	3	(	(	PUNCT
admet-505	657	4	a)-(c)/(f)-(h	a)-(c)/(f)-(h	NOUN
admet-505	657	5	)	)	PUNCT
admet-505	657	6	,	,	PUNCT
admet-505	657	7	eutectic	eutectic	ADJ
admet-505	657	8	conditions	condition	NOUN
admet-505	657	9	hold	hold	VERB
admet-505	657	10	up	up	ADP
admet-505	657	11	to	to	ADP
admet-505	657	12	ph	ph	PROPN
admet-505	657	13	3	3	NUM
admet-505	657	14	,	,	PUNCT
admet-505	657	15	above	above	ADP
admet-505	657	16	which	which	PRON
admet-505	657	17	,	,	PUNCT
admet-505	657	18	the	the	DET
admet-505	657	19	cocrystal	cocrystal	ADJ
admet-505	657	20	dissolves	dissolve	VERB
admet-505	657	21	but	but	CCONJ
admet-505	657	22	carbamazepine	carbamazepine	NOUN
admet-505	657	23	precipitate	precipitate	NOUN
admet-505	657	24	persists	persist	VERB
admet-505	657	25	.	.	PUNCT
admet-505	658	1	up	up	ADP
admet-505	658	2	to	to	PART
admet-505	658	3	44	44	NUM
admet-505	658	4	mm	mm	PROPN
admet-505	658	5	sds	sds	PROPN
admet-505	658	6	,	,	PUNCT
admet-505	658	7	the	the	DET
admet-505	658	8	coformer	coformer	NOUN
admet-505	658	9	eutectic	eutectic	ADJ
admet-505	658	10	curves	curve	NOUN
admet-505	658	11	are	be	AUX
admet-505	658	12	relatively	relatively	ADV
admet-505	658	13	unchanged	unchanged	ADJ
admet-505	658	14	,	,	PUNCT
admet-505	658	15	as	as	SCONJ
admet-505	658	16	the	the	DET
admet-505	658	17	api	api	NOUN
admet-505	658	18	curves	curve	NOUN
admet-505	658	19	are	be	AUX
admet-505	658	20	lifted	lift	VERB
admet-505	658	21	by	by	ADP
admet-505	658	22	the	the	DET
admet-505	658	23	added	add	VERB
admet-505	658	24	sds	sds	NOUN
admet-505	658	25	,	,	PUNCT
admet-505	658	26	creating	create	VERB
admet-505	658	27	cross	cross	ADJ
admet-505	658	28	-	-	ADJ
admet-505	658	29	over	over	ADP
admet-505	658	30	points	point	NOUN
admet-505	658	31	in	in	ADP
admet-505	658	32	frames	frame	NOUN
admet-505	658	33	(	(	PUNCT
admet-505	658	34	b	b	NOUN
admet-505	658	35	)	)	PUNCT
admet-505	658	36	and	and	CCONJ
admet-505	658	37	(	(	PUNCT
admet-505	658	38	c	c	NOUN
admet-505	658	39	)	)	PUNCT
admet-505	658	40	at	at	ADP
admet-505	658	41	ph	ph	PROPN
admet-505	658	42	1.7	1.7	NUM
admet-505	658	43	and	and	CCONJ
admet-505	658	44	2.2	2.2	NUM
admet-505	658	45	,	,	PUNCT
admet-505	658	46	respectively	respectively	ADV
admet-505	658	47	.	.	PUNCT
admet-505	659	1	at	at	ADP
admet-505	659	2	the	the	DET
admet-505	659	3	two	two	NUM
admet-505	659	4	highest	high	ADJ
admet-505	659	5	sds	sds	NOUN
admet-505	659	6	concentrations	concentration	NOUN
admet-505	659	7	,	,	PUNCT
admet-505	659	8	the	the	DET
admet-505	659	9	cross	cross	NOUN
admet-505	659	10	-	-	ADJ
admet-505	659	11	over	over	ADV
admet-505	659	12	is	be	AUX
admet-505	659	13	no	no	PRON
admet-505	659	14	longer	long	ADV
admet-505	659	15	evident	evident	ADJ
admet-505	659	16	,	,	PUNCT
admet-505	659	17	and	and	CCONJ
admet-505	659	18	even	even	ADV
admet-505	659	19	the	the	DET
admet-505	659	20	coformer	coformer	NOUN
admet-505	659	21	eutectic	eutectic	ADJ
admet-505	659	22	curves	curve	NOUN
admet-505	659	23	show	show	VERB
admet-505	659	24	upward	upward	ADJ
admet-505	659	25	lift	lift	NOUN
admet-505	659	26	(	(	PUNCT
admet-505	659	27	suggesting	suggest	VERB
admet-505	659	28	coformer	coformer	NOUN
admet-505	659	29	-	-	PUNCT
admet-505	659	30	micelle	micelle	NOUN
admet-505	659	31	complexes	complex	NOUN
admet-505	659	32	play	play	VERB
admet-505	659	33	a	a	DET
admet-505	659	34	role	role	NOUN
admet-505	659	35	)	)	PUNCT
admet-505	659	36	.	.	PUNCT
admet-505	660	1	the	the	DET
admet-505	660	2	250	250	NUM
admet-505	660	3	mm	mm	PROPN
admet-505	660	4	sds	sds	PROPN
admet-505	660	5	is	be	AUX
admet-505	660	6	sufficient	sufficient	ADJ
admet-505	660	7	to	to	PART
admet-505	660	8	dissolve	dissolve	VERB
admet-505	660	9	the	the	DET
admet-505	660	10	excess	excess	ADJ
admet-505	660	11	api	api	NOUN
admet-505	660	12	at	at	ADP
admet-505	660	13	low	low	ADJ
admet-505	660	14	ph	ph	VERB
admet-505	660	15	,	,	PUNCT
admet-505	660	16	to	to	PART
admet-505	660	17	form	form	VERB
admet-505	660	18	a	a	DET
admet-505	660	19	“	"	PUNCT
admet-505	660	20	eutectoid	eutectoid	ADJ
admet-505	660	21	”	"	PUNCT
admet-505	660	22	state	state	NOUN
admet-505	660	23	(	(	PUNCT
admet-505	660	24	only	only	ADV
admet-505	660	25	cc	cc	ADP
admet-505	660	26	precipitates	precipitate	NOUN
admet-505	660	27	;	;	PUNCT
admet-505	661	1	cf	cf	X
admet-505	661	2	.	.	PUNCT
admet-505	661	3	glossary	glossary	NOUN
admet-505	661	4	)	)	PUNCT
admet-505	661	5	,	,	PUNCT
admet-505	661	6	but	but	CCONJ
admet-505	661	7	only	only	ADV
admet-505	661	8	up	up	ADP
admet-505	661	9	to	to	ADP
admet-505	661	10	ph	ph	PROPN
admet-505	661	11	2.69	2.69	NUM
admet-505	661	12	(	(	PUNCT
admet-505	661	13	fig	fig	NOUN
admet-505	661	14	.	.	PUNCT
admet-505	661	15	11i	11i	NOUN
admet-505	661	16	)	)	PUNCT
admet-505	661	17	.	.	PUNCT
admet-505	662	1	between	between	ADP
admet-505	662	2	ph	ph	PROPN
admet-505	662	3	2.69	2.69	NUM
admet-505	662	4	and	and	CCONJ
admet-505	662	5	2.90	2.90	NUM
admet-505	662	6	,	,	PUNCT
admet-505	662	7	a	a	DET
admet-505	662	8	narrow	narrow	ADJ
admet-505	662	9	eutectic	eutectic	ADJ
admet-505	662	10	state	state	NOUN
admet-505	662	11	is	be	AUX
admet-505	662	12	predicted	predict	VERB
admet-505	662	13	to	to	PART
admet-505	662	14	form	form	VERB
admet-505	662	15	,	,	PUNCT
admet-505	662	16	as	as	SCONJ
admet-505	662	17	the	the	DET
admet-505	662	18	sds	sds	NOUN
admet-505	662	19	can	can	AUX
admet-505	662	20	not	not	PART
admet-505	662	21	suppress	suppress	VERB
admet-505	662	22	some	some	DET
admet-505	662	23	api	api	NOUN
admet-505	662	24	from	from	ADP
admet-505	662	25	precipitating	precipitate	VERB
admet-505	662	26	.	.	PUNCT
admet-505	663	1	above	above	ADP
admet-505	663	2	ph	ph	PROPN
admet-505	663	3	2.9	2.9	NUM
admet-505	663	4	,	,	PUNCT
admet-505	663	5	the	the	DET
admet-505	663	6	api	api	NOUN
admet-505	663	7	remains	remain	VERB
admet-505	663	8	the	the	DET
admet-505	663	9	only	only	ADJ
admet-505	663	10	residual	residual	ADJ
admet-505	663	11	solid	solid	ADJ
admet-505	663	12	in	in	ADP
admet-505	663	13	the	the	DET
admet-505	663	14	suspension	suspension	NOUN
admet-505	663	15	,	,	PUNCT
admet-505	663	16	as	as	SCONJ
admet-505	663	17	all	all	PRON
admet-505	663	18	of	of	ADP
admet-505	663	19	the	the	DET
admet-505	663	20	cc	cc	PROPN
admet-505	663	21	dissolves	dissolve	VERB
admet-505	663	22	.	.	PUNCT
admet-505	664	1	at	at	ADP
admet-505	664	2	the	the	DET
admet-505	664	3	highest	high	ADJ
admet-505	664	4	sds	sds	NOUN
admet-505	664	5	concentration	concentration	NOUN
admet-505	664	6	,	,	PUNCT
admet-505	664	7	the	the	DET
admet-505	664	8	api	api	NOUN
admet-505	664	9	is	be	AUX
admet-505	664	10	entirely	entirely	ADV
admet-505	664	11	micellized	micellize	VERB
admet-505	664	12	across	across	ADP
admet-505	664	13	the	the	DET
admet-505	664	14	whole	whole	ADJ
admet-505	664	15	ph	ph	ADJ
admet-505	664	16	range	range	NOUN
admet-505	664	17	.	.	PUNCT
admet-505	665	1	the	the	DET
admet-505	665	2	eutectoid	eutectoid	PROPN
admet-505	665	3	zone	zone	NOUN
admet-505	665	4	is	be	AUX
admet-505	665	5	thermodynamically	thermodynamically	ADV
admet-505	665	6	stable	stable	ADJ
admet-505	665	7	up	up	ADP
admet-505	665	8	to	to	ADP
admet-505	665	9	ph	ph	PROPN
admet-505	665	10	2.32	2.32	NUM
admet-505	665	11	,	,	PUNCT
admet-505	665	12	above	above	ADP
admet-505	665	13	which	which	PRON
admet-505	665	14	all	all	DET
admet-505	665	15	solids	solid	NOUN
admet-505	665	16	dissolve	dissolve	VERB
admet-505	665	17	(	(	PUNCT
admet-505	665	18	fig	fig	NOUN
admet-505	665	19	.	.	PUNCT
admet-505	665	20	11j	11j	NUM
admet-505	665	21	)	)	PUNCT
admet-505	665	22	.	.	PUNCT
admet-505	666	1	the	the	DET
admet-505	666	2	same	same	ADJ
admet-505	666	3	sample	sample	NOUN
admet-505	666	4	weights	weight	NOUN
admet-505	666	5	and	and	CCONJ
admet-505	666	6	the	the	DET
admet-505	666	7	same	same	ADJ
admet-505	666	8	equilibrium	equilibrium	NOUN
admet-505	666	9	constants	constant	NOUN
admet-505	666	10	were	be	AUX
admet-505	666	11	used	use	VERB
admet-505	666	12	for	for	ADP
admet-505	666	13	all	all	PRON
admet-505	666	14	of	of	ADP
admet-505	666	15	the	the	DET
admet-505	666	16	sds	sds	NOUN
admet-505	666	17	-	-	PUNCT
admet-505	666	18	containing	contain	VERB
admet-505	666	19	solutions	solution	NOUN
admet-505	666	20	.	.	PUNCT
admet-505	667	1	atazanavir	atazanavir	PROPN
admet-505	667	2	:	:	PUNCT
admet-505	667	3	pterostilbene	pterostilbene	NOUN
admet-505	667	4	1:1	1:1	NUM
admet-505	667	5	cocrystal	cocrystal	ADJ
admet-505	667	6	–	–	PUNCT
admet-505	667	7	exploratory	exploratory	ADJ
admet-505	667	8	simulation	simulation	NOUN
admet-505	667	9	of	of	ADP
admet-505	667	10	an	an	DET
admet-505	667	11	unmeasured	unmeasured	ADJ
admet-505	667	12	system	system	NOUN
admet-505	667	13	given	give	VERB
admet-505	667	14	that	that	PRON
admet-505	667	15	one	one	NOUN
admet-505	667	16	can	can	AUX
admet-505	667	17	predict	predict	VERB
admet-505	667	18	k	k	PROPN
admet-505	667	19	and	and	CCONJ
admet-505	667	20	ksp	ksp	PROPN
admet-505	667	21	cc	cc	PROPN
admet-505	667	22	,	,	PUNCT
admet-505	667	23	it	it	PRON
admet-505	667	24	was	be	AUX
admet-505	667	25	of	of	ADP
admet-505	667	26	interest	interest	NOUN
admet-505	667	27	to	to	PART
admet-505	667	28	consider	consider	VERB
admet-505	667	29	if	if	SCONJ
admet-505	667	30	a	a	DET
admet-505	667	31	cocrystal	cocrystal	NOUN
admet-505	667	32	between	between	ADP
admet-505	667	33	atazanavir	atazanavir	PROPN
admet-505	667	34	and	and	CCONJ
admet-505	667	35	pterostilbene	pterostilbene	NOUN
admet-505	667	36	could	could	AUX
admet-505	667	37	form	form	VERB
admet-505	667	38	.	.	PUNCT
admet-505	668	1	there	there	PRON
admet-505	668	2	are	be	VERB
admet-505	668	3	no	no	DET
admet-505	668	4	reports	report	NOUN
admet-505	668	5	of	of	ADP
admet-505	668	6	such	such	DET
admet-505	668	7	a	a	DET
admet-505	668	8	system	system	NOUN
admet-505	668	9	in	in	ADP
admet-505	668	10	the	the	DET
admet-505	668	11	literature	literature	NOUN
admet-505	668	12	.	.	PUNCT
admet-505	669	1	two	two	NUM
admet-505	669	2	main	main	ADJ
admet-505	669	3	sets	set	NOUN
admet-505	669	4	of	of	ADP
admet-505	669	5	conditions	condition	NOUN
admet-505	669	6	were	be	AUX
admet-505	669	7	explored	explore	VERB
admet-505	669	8	in	in	ADP
admet-505	669	9	the	the	DET
admet-505	669	10	simulated	simulated	ADJ
admet-505	669	11	data	datum	NOUN
admet-505	669	12	:	:	PUNCT
admet-505	669	13	atazanavir	atazanavir	PROPN
admet-505	669	14	cocrystal	cocrystal	PROPN
admet-505	669	15	added	add	VERB
admet-505	669	16	to	to	ADP
admet-505	669	17	solution	solution	NOUN
admet-505	669	18	with	with	ADP
admet-505	669	19	and	and	CCONJ
admet-505	669	20	without	without	ADP
admet-505	669	21	excess	excess	ADJ
admet-505	669	22	drug	drug	NOUN
admet-505	669	23	.	.	PUNCT
admet-505	670	1	in	in	ADP
admet-505	670	2	each	each	DET
admet-505	670	3	case	case	NOUN
admet-505	670	4	,	,	PUNCT
admet-505	670	5	0	0	NUM
admet-505	670	6	,	,	PUNCT
admet-505	670	7	10	10	NUM
admet-505	670	8	,	,	PUNCT
admet-505	670	9	and	and	CCONJ
admet-505	670	10	20	20	NUM
admet-505	670	11	mm	mm	NOUN
admet-505	670	12	[	[	NOUN
admet-505	670	13	sds]tot	sds]tot	NOUN
admet-505	670	14	were	be	AUX
admet-505	670	15	part	part	NOUN
admet-505	670	16	of	of	ADP
admet-505	670	17	the	the	DET
admet-505	670	18	simulation	simulation	NOUN
admet-505	670	19	compositions	composition	NOUN
admet-505	670	20	.	.	PUNCT
admet-505	671	1	the	the	DET
admet-505	671	2	equilibrium	equilibrium	NOUN
admet-505	671	3	constants	constant	NOUN
admet-505	671	4	(	(	PUNCT
admet-505	671	5	37	37	NUM
admet-505	671	6	°	°	NOUN
admet-505	671	7	c	c	NOUN
admet-505	671	8	)	)	PUNCT
admet-505	671	9	used	use	VERB
admet-505	671	10	in	in	ADP
admet-505	671	11	the	the	DET
admet-505	671	12	calculations	calculation	NOUN
admet-505	671	13	are	be	AUX
admet-505	671	14	listed	list	VERB
admet-505	671	15	in	in	ADP
admet-505	671	16	figure	figure	NOUN
admet-505	671	17	12a	12a	NOUN
admet-505	671	18	.	.	PUNCT
admet-505	672	1	the	the	DET
admet-505	672	2	pka	pka	PROPN
admet-505	672	3	and	and	CCONJ
admet-505	672	4	s0	s0	PROPN
admet-505	672	5	were	be	AUX
admet-505	672	6	determined	determine	VERB
admet-505	672	7	by	by	ADP
admet-505	672	8	analysis	analysis	NOUN
admet-505	672	9	of	of	ADP
admet-505	672	10	the	the	DET
admet-505	672	11	atazanavir	atazanavir	PROPN
admet-505	672	12	-	-	PUNCT
admet-505	672	13	sds	sds	PROPN
admet-505	672	14	data	datum	NOUN
admet-505	672	15	from	from	ADP
admet-505	672	16	indulkar	indulkar	PROPN
admet-505	672	17	et	et	PROPN
admet-505	672	18	al	al	PROPN
admet-505	672	19	.	.	PUNCT
admet-505	673	1	[	[	X
admet-505	673	2	20	20	NUM
admet-505	673	3	]	]	PUNCT
admet-505	673	4	.	.	PUNCT
admet-505	674	1	the	the	DET
admet-505	674	2	pterostilbene	pterostilbene	NOUN
admet-505	674	3	s0	s0	PROPN
admet-505	674	4	was	be	AUX
admet-505	674	5	determined	determine	VERB
admet-505	674	6	from	from	ADP
admet-505	674	7	data	datum	NOUN
admet-505	674	8	in	in	ADP
admet-505	674	9	[	[	X
admet-505	674	10	65	65	NUM
admet-505	674	11	]	]	PUNCT
admet-505	674	12	,	,	PUNCT
admet-505	674	13	using	use	VERB
admet-505	674	14	the	the	DET
admet-505	674	15	pka	pka	PROPN
admet-505	674	16	cof	cof	PROPN
admet-505	674	17	estimated	estimate	VERB
admet-505	674	18	from	from	ADP
admet-505	674	19	2d	2d	NUM
admet-505	674	20	structure	structure	NOUN
admet-505	674	21	.	.	PUNCT
admet-505	675	1	cocrystal	cocrystal	PROPN
admet-505	675	2	ksp	ksp	PROPN
admet-505	675	3	was	be	AUX
admet-505	675	4	estimated	estimate	VERB
admet-505	675	5	by	by	ADP
admet-505	675	6	the	the	DET
admet-505	675	7	method	method	NOUN
admet-505	675	8	described	describe	VERB
admet-505	675	9	elsewhere	elsewhere	ADV
admet-505	675	10	[	[	X
admet-505	675	11	17	17	NUM
admet-505	675	12	]	]	PUNCT
admet-505	675	13	.	.	PUNCT
admet-505	676	1	kn	kn	PROPN
admet-505	676	2	was	be	AUX
admet-505	676	3	estimated	estimate	VERB
admet-505	676	4	by	by	ADP
admet-505	676	5	eq	eq	PROPN
admet-505	676	6	.	.	PUNCT
admet-505	677	1	(	(	PUNCT
admet-505	677	2	13	13	NUM
admet-505	677	3	)	)	PUNCT
admet-505	677	4	.	.	PUNCT
admet-505	678	1	in	in	ADP
admet-505	678	2	the	the	DET
admet-505	678	3	simulations	simulation	NOUN
admet-505	678	4	in	in	ADP
admet-505	678	5	figure	figure	NOUN
admet-505	678	6	12	12	NUM
admet-505	678	7	,	,	PUNCT
admet-505	678	8	all	all	DET
admet-505	678	9	cases	case	NOUN
admet-505	678	10	were	be	AUX
admet-505	678	11	based	base	VERB
admet-505	678	12	on	on	ADP
admet-505	678	13	100	100	NUM
admet-505	678	14	mg	mg	NUM
admet-505	678	15	/	/	SYM
admet-505	678	16	ml	ml	NOUN
admet-505	678	17	cc	cc	AUX
admet-505	678	18	added	add	VERB
admet-505	678	19	to	to	ADP
admet-505	678	20	water	water	NOUN
admet-505	678	21	,	,	PUNCT
admet-505	678	22	with	with	ADP
admet-505	678	23	ph	ph	NOUN
admet-505	678	24	adjusted	adjust	VERB
admet-505	678	25	using	use	VERB
admet-505	678	26	either	either	CCONJ
admet-505	678	27	1	1	NUM
admet-505	678	28	m	m	NOUN
admet-505	678	29	hcl	hcl	PROPN
admet-505	678	30	or	or	CCONJ
admet-505	678	31	naoh	naoh	NOUN
admet-505	678	32	.	.	PUNCT
admet-505	679	1	in	in	ADP
admet-505	679	2	the	the	DET
admet-505	679	3	figure	figure	NOUN
admet-505	679	4	13	13	NUM
admet-505	679	5	cases	case	NOUN
admet-505	679	6	,	,	PUNCT
admet-505	679	7	excess	excess	ADJ
admet-505	679	8	api	api	NOUN
admet-505	679	9	,	,	PUNCT
admet-505	679	10	50	50	NUM
admet-505	679	11	mg	mg	NUM
admet-505	679	12	/	/	SYM
admet-505	679	13	ml	ml	PROPN
admet-505	679	14	,	,	PUNCT
admet-505	679	15	was	be	AUX
admet-505	679	16	added	add	VERB
admet-505	679	17	to	to	ADP
admet-505	679	18	the	the	DET
admet-505	679	19	simulated	simulate	VERB
admet-505	679	20	solutions	solution	NOUN
admet-505	679	21	,	,	PUNCT
admet-505	679	22	in	in	ADP
admet-505	679	23	addition	addition	NOUN
admet-505	679	24	to	to	ADP
admet-505	679	25	the	the	DET
admet-505	679	26	100	100	NUM
admet-505	679	27	mg	mg	NUM
admet-505	679	28	/	/	SYM
admet-505	679	29	ml	ml	PROPN
admet-505	679	30	cc	cc	PROPN
admet-505	679	31	.	.	PROPN
admet-505	679	32	figure	figure	PROPN
admet-505	679	33	12a	12a	NOUN
admet-505	679	34	shows	show	VERB
admet-505	679	35	the	the	DET
admet-505	679	36	predicted	predict	VERB
admet-505	679	37	eutectoid	eutectoid	ADJ
admet-505	679	38	-	-	PUNCT
admet-505	679	39	eutectic	eutectic	ADJ
admet-505	679	40	concentration	concentration	NOUN
admet-505	679	41	curves	curve	NOUN
admet-505	679	42	for	for	ADP
admet-505	679	43	the	the	DET
admet-505	679	44	system	system	NOUN
admet-505	679	45	in	in	ADP
admet-505	679	46	the	the	DET
admet-505	679	47	absence	absence	NOUN
admet-505	679	48	surfactant	surfactant	NOUN
admet-505	679	49	.	.	PUNCT
admet-505	680	1	below	below	ADP
admet-505	680	2	ph	ph	PROPN
admet-505	680	3	3.23	3.23	NUM
admet-505	680	4	,	,	PUNCT
admet-505	680	5	the	the	DET
admet-505	680	6	system	system	NOUN
admet-505	680	7	is	be	AUX
admet-505	680	8	thermodynamically	thermodynamically	ADV
admet-505	680	9	stable	stable	ADJ
admet-505	680	10	as	as	ADP
admet-505	680	11	a	a	DET
admet-505	680	12	eutectoid	eutectoid	NOUN
admet-505	680	13	(	(	PUNCT
admet-505	680	14	cf	cf	NOUN
admet-505	680	15	.	.	PUNCT
admet-505	680	16	,	,	PUNCT
admet-505	680	17	glossary	glossary	NOUN
admet-505	680	18	)	)	PUNCT
admet-505	680	19	.	.	PUNCT
admet-505	681	1	the	the	DET
admet-505	681	2	eutectoid	eutectoid	PROPN
admet-505	681	3	admet	admet	PROPN
admet-505	681	4	&	&	CCONJ
admet-505	681	5	dmpk	dmpk	PROPN
admet-505	681	6	6(2	6(2	NUM
admet-505	681	7	)	)	PUNCT
admet-505	681	8	(	(	PUNCT
admet-505	681	9	2018	2018	NUM
admet-505	681	10	)	)	PUNCT
admet-505	681	11	105	105	NUM
admet-505	681	12	-	-	SYM
admet-505	681	13	139	139	NUM
admet-505	681	14	cocrystal	cocrystal	ADJ
admet-505	681	15	solubility	solubility	NOUN
admet-505	681	16	-	-	PUNCT
admet-505	681	17	ph	ph	VERB
admet-505	681	18	,	,	PUNCT
admet-505	681	19	drug	drug	NOUN
admet-505	681	20	solubilization	solubilization	NOUN
admet-505	681	21	capacity	capacity	NOUN
admet-505	681	22	of	of	ADP
admet-505	681	23	sds	sds	PROPN
admet-505	681	24	,	,	PUNCT
admet-505	681	25	mass	mass	ADJ
admet-505	681	26	action	action	NOUN
admet-505	681	27	model	model	NOUN
admet-505	681	28	doi	doi	PROPN
admet-505	681	29	:	:	PUNCT
admet-505	681	30	10.5599	10.5599	NUM
admet-505	681	31	/	/	SYM
admet-505	681	32	admet.505	admet.505	PROPN
admet-505	681	33	129	129	NUM
admet-505	681	34	concentration	concentration	NOUN
admet-505	681	35	of	of	ADP
admet-505	681	36	atazanavir	atazanavir	PROPN
admet-505	681	37	is	be	AUX
admet-505	681	38	lower	low	ADJ
admet-505	681	39	than	than	ADP
admet-505	681	40	that	that	PRON
admet-505	681	41	found	find	VERB
admet-505	681	42	in	in	ADP
admet-505	681	43	non	non	ADJ
admet-505	681	44	-	-	ADJ
admet-505	681	45	cc	cc	ADJ
admet-505	681	46	systems	system	NOUN
admet-505	681	47	.	.	PUNCT
admet-505	682	1	that	that	PRON
admet-505	682	2	of	of	ADP
admet-505	682	3	the	the	DET
admet-505	682	4	pterostilbene	pterostilbene	NOUN
admet-505	682	5	is	be	AUX
admet-505	682	6	largely	largely	ADV
admet-505	682	7	elevated	elevate	VERB
admet-505	682	8	from	from	ADP
admet-505	682	9	its	its	PRON
admet-505	682	10	non	non	ADJ
admet-505	682	11	-	-	ADJ
admet-505	682	12	cc	cc	ADJ
admet-505	682	13	value	value	NOUN
admet-505	682	14	.	.	PUNCT
admet-505	683	1	above	above	ADP
admet-505	683	2	ph	ph	PROPN
admet-505	683	3	3.23	3.23	NUM
admet-505	683	4	,	,	PUNCT
admet-505	683	5	the	the	DET
admet-505	683	6	cocrystal	cocrystal	ADJ
admet-505	683	7	system	system	NOUN
admet-505	683	8	unstitches	unstitche	NOUN
admet-505	683	9	into	into	ADP
admet-505	683	10	non	non	ADJ
admet-505	683	11	-	-	ADJ
admet-505	683	12	equivalent	equivalent	ADJ
admet-505	683	13	eutectic	eutectic	ADJ
admet-505	683	14	api	api	NOUN
admet-505	683	15	and	and	CCONJ
admet-505	683	16	coformer	coformer	NOUN
admet-505	683	17	concentrations	concentration	NOUN
admet-505	683	18	,	,	PUNCT
admet-505	683	19	with	with	ADP
admet-505	683	20	the	the	DET
admet-505	683	21	api	api	NOUN
admet-505	683	22	taking	taking	NOUN
admet-505	683	23	on	on	ADP
admet-505	683	24	the	the	DET
admet-505	683	25	thermodynamic	thermodynamic	ADJ
admet-505	683	26	values	value	NOUN
admet-505	683	27	observed	observe	VERB
admet-505	683	28	in	in	ADP
admet-505	683	29	the	the	DET
admet-505	683	30	non	non	ADJ
admet-505	683	31	-	-	ADJ
admet-505	683	32	cc	cc	ADJ
admet-505	683	33	system	system	NOUN
admet-505	683	34	.	.	PUNCT
admet-505	684	1	concomitantly	concomitantly	ADV
admet-505	684	2	,	,	PUNCT
admet-505	684	3	api	api	NOUN
admet-505	684	4	precipitates	precipitate	NOUN
admet-505	684	5	.	.	PUNCT
admet-505	685	1	the	the	DET
admet-505	685	2	thick	thick	ADJ
admet-505	685	3	dashed	dash	VERB
admet-505	685	4	purple	purple	NOUN
admet-505	685	5	,	,	PUNCT
admet-505	685	6	marking	mark	VERB
admet-505	685	7	scc	scc	NOUN
admet-505	685	8	,	,	PUNCT
admet-505	685	9	suggests	suggest	VERB
admet-505	685	10	an	an	DET
admet-505	685	11	enhanced	enhanced	ADJ
admet-505	685	12	,	,	PUNCT
admet-505	685	13	albeit	albeit	SCONJ
admet-505	685	14	transient	transient	ADJ
admet-505	685	15	,	,	PUNCT
admet-505	685	16	concentration	concentration	NOUN
admet-505	685	17	of	of	ADP
admet-505	685	18	the	the	DET
admet-505	685	19	api	api	NOUN
admet-505	685	20	.	.	PUNCT
admet-505	686	1	adding	add	VERB
admet-505	686	2	the	the	DET
admet-505	686	3	sds	sds	NOUN
admet-505	686	4	,	,	PUNCT
admet-505	686	5	as	as	ADP
admet-505	686	6	in	in	ADP
admet-505	686	7	frames	frame	NOUN
admet-505	686	8	(	(	PUNCT
admet-505	686	9	b	b	NOUN
admet-505	686	10	)	)	PUNCT
admet-505	686	11	and	and	CCONJ
admet-505	686	12	(	(	PUNCT
admet-505	686	13	c	c	X
admet-505	686	14	)	)	PUNCT
admet-505	686	15	has	have	VERB
admet-505	686	16	the	the	DET
admet-505	686	17	effect	effect	NOUN
admet-505	686	18	of	of	ADP
admet-505	686	19	“	"	PUNCT
admet-505	686	20	zippering	zippering	NOUN
admet-505	686	21	”	"	PUNCT
admet-505	686	22	the	the	DET
admet-505	686	23	eutectic	eutectic	NOUN
admet-505	686	24	to	to	ADP
admet-505	686	25	a	a	DET
admet-505	686	26	eutectoid	eutectoid	ADJ
admet-505	686	27	state	state	NOUN
admet-505	686	28	,	,	PUNCT
admet-505	686	29	to	to	ADP
admet-505	686	30	ph	ph	PROPN
admet-505	686	31	8.62	8.62	NUM
admet-505	686	32	in	in	ADP
admet-505	686	33	the	the	DET
admet-505	686	34	case	case	NOUN
admet-505	686	35	of	of	ADP
admet-505	686	36	10	10	NUM
admet-505	686	37	mm	mm	PROPN
admet-505	686	38	sds	sds	PROPN
admet-505	686	39	and	and	CCONJ
admet-505	686	40	9.79	9.79	NUM
admet-505	686	41	in	in	ADP
admet-505	686	42	the	the	DET
admet-505	686	43	case	case	NOUN
admet-505	686	44	of	of	ADP
admet-505	686	45	20	20	NUM
admet-505	686	46	mm	mm	PROPN
admet-505	686	47	sds	sds	PROPN
admet-505	686	48	.	.	PUNCT
admet-505	687	1	this	this	PRON
admet-505	687	2	has	have	VERB
admet-505	687	3	the	the	DET
admet-505	687	4	effect	effect	NOUN
admet-505	687	5	of	of	ADP
admet-505	687	6	re	re	VERB
admet-505	687	7	-	-	VERB
admet-505	687	8	dissolving	dissolve	VERB
admet-505	687	9	the	the	DET
admet-505	687	10	api	api	NOUN
admet-505	687	11	solid	solid	NOUN
admet-505	687	12	precipitated	precipitate	VERB
admet-505	687	13	in	in	ADP
admet-505	687	14	the	the	DET
admet-505	687	15	absence	absence	NOUN
admet-505	687	16	of	of	ADP
admet-505	687	17	the	the	DET
admet-505	687	18	surfactant	surfactant	NOUN
admet-505	687	19	.	.	PUNCT
admet-505	688	1	figure	figure	NOUN
admet-505	688	2	13	13	NUM
admet-505	688	3	shows	show	VERB
admet-505	688	4	the	the	DET
admet-505	688	5	simulated	simulated	ADJ
admet-505	688	6	atazanavir	atazanavir	PROPN
admet-505	688	7	:	:	PUNCT
admet-505	688	8	pterostilbene	pterostilbene	NOUN
admet-505	688	9	system	system	NOUN
admet-505	688	10	where	where	SCONJ
admet-505	688	11	the	the	DET
admet-505	688	12	cc	cc	NOUN
admet-505	688	13	is	be	AUX
admet-505	688	14	added	add	VERB
admet-505	688	15	along	along	ADP
admet-505	688	16	with	with	ADP
admet-505	688	17	an	an	DET
admet-505	688	18	excess	excess	NOUN
admet-505	688	19	of	of	ADP
admet-505	688	20	api	api	NOUN
admet-505	688	21	.	.	PUNCT
admet-505	689	1	the	the	DET
admet-505	689	2	main	main	ADJ
admet-505	689	3	effect	effect	NOUN
admet-505	689	4	is	be	AUX
admet-505	689	5	to	to	ADP
admet-505	689	6	“	"	PUNCT
admet-505	689	7	unzipper	unzipper	VERB
admet-505	689	8	”	"	PUNCT
admet-505	689	9	the	the	DET
admet-505	689	10	eutectoid	eutectoid	ADJ
admet-505	689	11	states	state	NOUN
admet-505	689	12	suggested	suggest	VERB
admet-505	689	13	in	in	ADP
admet-505	689	14	figure	figure	NOUN
admet-505	689	15	12	12	NUM
admet-505	689	16	.	.	PUNCT
admet-505	690	1	the	the	DET
admet-505	690	2	middle	middle	ADJ
admet-505	690	3	-	-	PUNCT
admet-505	690	4	ph	ph	NOUN
admet-505	690	5	region	region	NOUN
admet-505	690	6	in	in	ADP
admet-505	690	7	figure	figure	NOUN
admet-505	690	8	13b	13b	NOUN
admet-505	690	9	is	be	AUX
admet-505	690	10	nearly	nearly	ADV
admet-505	690	11	eutectoid	eutectoid	ADJ
admet-505	690	12	,	,	PUNCT
admet-505	690	13	but	but	CCONJ
admet-505	690	14	not	not	PART
admet-505	690	15	precisely	precisely	ADV
admet-505	690	16	so	so	ADV
admet-505	690	17	.	.	PUNCT
admet-505	691	1	the	the	DET
admet-505	691	2	simulations	simulation	NOUN
admet-505	691	3	in	in	ADP
admet-505	691	4	the	the	DET
admet-505	691	5	above	above	ADJ
admet-505	691	6	two	two	NUM
admet-505	691	7	figures	figure	NOUN
admet-505	691	8	illustrate	illustrate	VERB
admet-505	691	9	the	the	DET
admet-505	691	10	kind	kind	NOUN
admet-505	691	11	of	of	ADP
admet-505	691	12	exploratory	exploratory	ADJ
admet-505	691	13	investigations	investigation	NOUN
admet-505	691	14	that	that	PRON
admet-505	691	15	can	can	AUX
admet-505	691	16	be	be	AUX
admet-505	691	17	performed	perform	VERB
admet-505	691	18	quickly	quickly	ADV
admet-505	691	19	in	in	ADP
admet-505	691	20	silico	silico	NOUN
admet-505	691	21	,	,	PUNCT
admet-505	691	22	as	as	ADP
admet-505	691	23	part	part	NOUN
admet-505	691	24	of	of	ADP
admet-505	691	25	a	a	DET
admet-505	691	26	plan	plan	NOUN
admet-505	691	27	to	to	PART
admet-505	691	28	investigate	investigate	VERB
admet-505	691	29	a	a	DET
admet-505	691	30	potential	potential	ADJ
admet-505	691	31	cocrystal	cocrystal	ADJ
admet-505	691	32	system	system	NOUN
admet-505	691	33	.	.	PUNCT
admet-505	692	1	alex	alex	PROPN
admet-505	692	2	avdeef	avdeef	PROPN
admet-505	692	3	admet	admet	PROPN
admet-505	692	4	&	&	CCONJ
admet-505	692	5	dmpk	dmpk	PROPN
admet-505	692	6	6(2	6(2	NUM
admet-505	692	7	)	)	PUNCT
admet-505	692	8	(	(	PUNCT
admet-505	692	9	2018	2018	NUM
admet-505	692	10	)	)	PUNCT
admet-505	692	11	105	105	NUM
admet-505	692	12	-	-	SYM
admet-505	692	13	139	139	NUM
admet-505	692	14	130	130	NUM
admet-505	692	15	figure	figure	NOUN
admet-505	692	16	11	11	NUM
admet-505	692	17	.	.	PUNCT
admet-505	693	1	carbamazepine	carbamazepine	NOUN
admet-505	693	2	:	:	PUNCT
admet-505	693	3	saccharin	saccharin	NOUN
admet-505	693	4	1:1	1:1	NUM
admet-505	693	5	cocrystal	cocrystal	NOUN
admet-505	693	6	(	(	PUNCT
admet-505	693	7	data	data	NOUN
admet-505	693	8	points	point	NOUN
admet-505	693	9	from	from	ADP
admet-505	693	10	[	[	X
admet-505	693	11	9	9	NUM
admet-505	693	12	]	]	PUNCT
admet-505	693	13	and	and	CCONJ
admet-505	693	14	[	[	X
admet-505	693	15	64	64	NUM
admet-505	693	16	]	]	PUNCT
admet-505	693	17	)	)	PUNCT
admet-505	693	18	.	.	PUNCT
admet-505	694	1	in	in	ADP
admet-505	694	2	all	all	DET
admet-505	694	3	cases	case	NOUN
admet-505	694	4	,	,	PUNCT
admet-505	694	5	the	the	DET
admet-505	694	6	added	add	VERB
admet-505	694	7	cc	cc	NOUN
admet-505	694	8	and	and	CCONJ
admet-505	694	9	excess	excess	ADJ
admet-505	694	10	api	api	NOUN
admet-505	694	11	weights	weight	NOUN
admet-505	694	12	were	be	AUX
admet-505	694	13	assumed	assume	VERB
admet-505	694	14	to	to	PART
admet-505	694	15	be	be	AUX
admet-505	694	16	70	70	NUM
admet-505	694	17	mg	mg	NUM
admet-505	694	18	/	/	SYM
admet-505	694	19	ml	ml	NOUN
admet-505	694	20	and	and	CCONJ
admet-505	694	21	35	35	NUM
admet-505	694	22	mg	mg	NUM
admet-505	694	23	/	/	SYM
admet-505	694	24	ml	ml	NOUN
admet-505	694	25	,	,	PUNCT
admet-505	694	26	respectively	respectively	ADV
admet-505	694	27	.	.	PUNCT
admet-505	695	1	the	the	DET
admet-505	695	2	constants	constant	NOUN
admet-505	695	3	used	use	VERB
admet-505	695	4	(	(	PUNCT
admet-505	695	5	25	25	NUM
admet-505	695	6	°	°	NOUN
admet-505	695	7	c	c	NOUN
admet-505	695	8	,	,	PUNCT
admet-505	695	9	iref	iref	NOUN
admet-505	695	10	=	=	PUNCT
admet-505	695	11	0.2	0.2	NUM
admet-505	695	12	m	m	VERB
admet-505	695	13	)	)	PUNCT
admet-505	695	14	were	be	AUX
admet-505	695	15	:	:	PUNCT
admet-505	695	16	pka	pka	PROPN
admet-505	695	17	cof	cof	PROPN
admet-505	695	18	=	=	PROPN
admet-505	695	19	1.31	1.31	NUM
admet-505	695	20	,	,	PUNCT
admet-505	695	21	log	log	PROPN
admet-505	695	22	ksp	ksp	PROPN
admet-505	695	23	=	=	PROPN
admet-505	695	24	-6.01	-6.01	PROPN
admet-505	695	25	,	,	PUNCT
admet-505	695	26	log	log	NOUN
admet-505	695	27	s0	s0	NOUN
admet-505	695	28	=	=	SYM
admet-505	695	29	-3.26	-3.26	ADJ
admet-505	695	30	,	,	PUNCT
admet-505	695	31	log	log	VERB
admet-505	695	32	k32	k32	PROPN
admet-505	695	33	cof	cof	PROPN
admet-505	695	34	=	=	NOUN
admet-505	695	35	58.9	58.9	NUM
admet-505	695	36	,	,	PUNCT
admet-505	695	37	and	and	CCONJ
admet-505	695	38	log	log	VERB
admet-505	695	39	k22	k22	NOUN
admet-505	695	40	=	=	NOUN
admet-505	695	41	84.0	84.0	NUM
admet-505	695	42	.	.	PUNCT
admet-505	696	1	(	(	PUNCT
admet-505	696	2	a)-(e	a)-(e	NOUN
admet-505	696	3	):	):	PUNCT
admet-505	696	4	the	the	DET
admet-505	696	5	log	log	NOUN
admet-505	696	6	ctot	ctot	NOUN
admet-505	696	7	-	-	PUNCT
admet-505	696	8	ph	ph	ADJ
admet-505	696	9	profiles	profile	NOUN
admet-505	696	10	as	as	ADP
admet-505	696	11	thick	thick	ADJ
admet-505	696	12	solid	solid	ADJ
admet-505	696	13	red	red	NOUN
admet-505	696	14	(	(	PUNCT
admet-505	696	15	[	[	X
admet-505	696	16	api]tot	api]tot	NOUN
admet-505	696	17	)	)	PUNCT
admet-505	696	18	and	and	CCONJ
admet-505	696	19	blue	blue	ADJ
admet-505	696	20	(	(	PUNCT
admet-505	696	21	[	[	X
admet-505	696	22	cof]tot	cof]tot	NOUN
admet-505	696	23	)	)	PUNCT
admet-505	696	24	curves	curve	NOUN
admet-505	696	25	refer	refer	VERB
admet-505	696	26	to	to	ADP
admet-505	696	27	the	the	DET
admet-505	696	28	calculated	calculate	VERB
admet-505	696	29	(	(	PUNCT
admet-505	696	30	best	well	ADV
admet-505	696	31	-	-	PUNCT
admet-505	696	32	fit	fit	ADJ
admet-505	696	33	)	)	PUNCT
admet-505	696	34	total	total	ADJ
admet-505	696	35	aqueous	aqueous	ADJ
admet-505	696	36	concentrations	concentration	NOUN
admet-505	696	37	in	in	ADP
admet-505	696	38	saturated	saturated	ADJ
admet-505	696	39	solutions	solution	NOUN
admet-505	696	40	containing	contain	VERB
admet-505	696	41	increasing	increase	VERB
admet-505	696	42	concentrations	concentration	NOUN
admet-505	696	43	of	of	ADP
admet-505	696	44	sds	sds	PROPN
admet-505	696	45	.	.	PUNCT
admet-505	697	1	the	the	DET
admet-505	697	2	symbols	symbol	NOUN
admet-505	697	3	:	:	PUNCT
admet-505	697	4	red	red	ADJ
admet-505	697	5	circle	circle	NOUN
admet-505	697	6	(	(	PUNCT
admet-505	697	7	[	[	X
admet-505	697	8	api]tot	api]tot	NOUN
admet-505	697	9	,	,	PUNCT
admet-505	697	10	eu	eu	NOUN
admet-505	697	11	)	)	PUNCT
admet-505	697	12	and	and	CCONJ
admet-505	697	13	blue	blue	ADJ
admet-505	697	14	square	square	NOUN
admet-505	697	15	(	(	PUNCT
admet-505	697	16	[	[	X
admet-505	697	17	cof]tot	cof]tot	NOUN
admet-505	697	18	,	,	PUNCT
admet-505	697	19	eu	eu	NOUN
admet-505	697	20	)	)	PUNCT
admet-505	697	21	refer	refer	VERB
admet-505	697	22	to	to	ADP
admet-505	697	23	the	the	DET
admet-505	697	24	reported	report	VERB
admet-505	697	25	eutectic	eutectic	ADJ
admet-505	697	26	total	total	ADJ
admet-505	697	27	concentrations	concentration	NOUN
admet-505	697	28	[	[	X
admet-505	697	29	9	9	NUM
admet-505	697	30	,	,	PUNCT
admet-505	697	31	64	64	NUM
admet-505	697	32	]	]	PUNCT
admet-505	697	33	.	.	PUNCT
admet-505	698	1	the	the	DET
admet-505	698	2	thick	thick	ADJ
admet-505	698	3	dashed	dash	VERB
admet-505	698	4	purple	purple	ADJ
admet-505	698	5	curve	curve	NOUN
admet-505	698	6	(	(	PUNCT
admet-505	698	7	bounded	bound	VERB
admet-505	698	8	by	by	ADP
admet-505	698	9	the	the	DET
admet-505	698	10	api	api	NOUN
admet-505	698	11	and	and	CCONJ
admet-505	698	12	coformer	coformer	NOUN
admet-505	698	13	curves	curve	NOUN
admet-505	698	14	)	)	PUNCT
admet-505	698	15	refers	refer	VERB
admet-505	698	16	to	to	ADP
admet-505	698	17	the	the	DET
admet-505	698	18	calculated	calculated	ADJ
admet-505	698	19	scc	scc	PROPN
admet-505	698	20	.	.	PUNCT
admet-505	699	1	(	(	PUNCT
admet-505	699	2	f)-(j	f)-(j	PROPN
admet-505	699	3	):	):	PUNCT
admet-505	699	4	the	the	DET
admet-505	699	5	log	log	NOUN
admet-505	699	6	speciation	speciation	NOUN
admet-505	699	7	-	-	PUNCT
admet-505	699	8	ph	ph	NOUN
admet-505	699	9	profiles	profile	NOUN
admet-505	699	10	relate	relate	VERB
admet-505	699	11	the	the	DET
admet-505	699	12	concentrations	concentration	NOUN
admet-505	699	13	of	of	ADP
admet-505	699	14	various	various	ADJ
admet-505	699	15	(	(	PUNCT
admet-505	699	16	reactant	reactant	NOUN
admet-505	699	17	and	and	CCONJ
admet-505	699	18	product	product	NOUN
admet-505	699	19	)	)	PUNCT
admet-505	699	20	species	specie	NOUN
admet-505	699	21	to	to	ADP
admet-505	699	22	ph	ph	PROPN
admet-505	699	23	.	.	PUNCT
admet-505	700	1	the	the	DET
admet-505	700	2	color	color	NOUN
admet-505	700	3	assignments	assignment	NOUN
admet-505	700	4	are	be	AUX
admet-505	700	5	the	the	DET
admet-505	700	6	same	same	ADJ
admet-505	700	7	as	as	ADP
admet-505	700	8	before	before	ADV
admet-505	700	9	.	.	PUNCT
admet-505	701	1	the	the	DET
admet-505	701	2	thick	thick	ADJ
admet-505	701	3	solid	solid	ADJ
admet-505	701	4	curves	curve	NOUN
admet-505	701	5	refer	refer	VERB
admet-505	701	6	to	to	ADP
admet-505	701	7	the	the	DET
admet-505	701	8	carbamazepine	carbamazepine	NOUN
admet-505	701	9	(	(	PUNCT
admet-505	701	10	log	log	VERB
admet-505	701	11	[	[	X
admet-505	701	12	api0	api0	PROPN
admet-505	701	13	]	]	X
admet-505	701	14	)	)	PUNCT
admet-505	701	15	and	and	CCONJ
admet-505	701	16	the	the	DET
admet-505	701	17	uncharged	uncharged	ADJ
admet-505	701	18	form	form	NOUN
admet-505	701	19	of	of	ADP
admet-505	701	20	saccharin	saccharin	NOUN
admet-505	701	21	(	(	PUNCT
admet-505	701	22	log	log	NOUN
admet-505	702	1	[	[	X
admet-505	702	2	cof0	cof0	NOUN
admet-505	702	3	]	]	PUNCT
admet-505	702	4	)	)	PUNCT
admet-505	702	5	.	.	PUNCT
admet-505	703	1	the	the	DET
admet-505	703	2	corresponding	corresponding	ADJ
admet-505	703	3	charged	charge	VERB
admet-505	703	4	forms	form	NOUN
admet-505	703	5	are	be	AUX
admet-505	703	6	indicated	indicate	VERB
admet-505	703	7	by	by	ADP
admet-505	703	8	dash	dash	NOUN
admet-505	703	9	-	-	PUNCT
admet-505	703	10	dot	dot	NOUN
admet-505	703	11	curves	curve	NOUN
admet-505	703	12	.	.	PUNCT
admet-505	704	1	the	the	DET
admet-505	704	2	vertical	vertical	ADJ
admet-505	704	3	dashed	dash	VERB
admet-505	704	4	lines	line	NOUN
admet-505	704	5	mark	mark	VERB
admet-505	704	6	cocrystal	cocrystal	ADJ
admet-505	704	7	ph	ph	ADJ
admet-505	704	8	boundaries	boundary	NOUN
admet-505	704	9	of	of	ADP
admet-505	704	10	the	the	DET
admet-505	704	11	eutectic	eutectic	ADJ
admet-505	704	12	and	and	CCONJ
admet-505	704	13	eutectoid	eutectoid	ADJ
admet-505	704	14	zones	zone	NOUN
admet-505	704	15	.	.	PUNCT
admet-505	705	1	the	the	DET
admet-505	705	2	dotted	dotted	ADJ
admet-505	705	3	curves	curve	NOUN
admet-505	705	4	ascending	ascend	VERB
admet-505	705	5	/	/	SYM
admet-505	705	6	descending	descend	VERB
admet-505	705	7	from	from	ADP
admet-505	705	8	log	log	NOUN
admet-505	705	9	c	c	NOUN
admet-505	705	10	=	=	SYM
admet-505	705	11	0	0	NUM
admet-505	705	12	upper	upper	ADJ
admet-505	705	13	limit	limit	NOUN
admet-505	705	14	,	,	PUNCT
admet-505	705	15	indicated	indicate	VERB
admet-505	705	16	by	by	ADP
admet-505	705	17	black	black	ADJ
admet-505	705	18	❶	❶	PROPN
admet-505	705	19	in	in	ADP
admet-505	705	20	the	the	DET
admet-505	705	21	case	case	NOUN
admet-505	705	22	of	of	ADP
admet-505	705	23	the	the	DET
admet-505	705	24	cc	cc	PROPN
admet-505	705	25	and	and	CCONJ
admet-505	705	26	red	red	ADJ
admet-505	705	27	❷	❷	NUM
admet-505	705	28	in	in	ADP
admet-505	705	29	the	the	DET
admet-505	705	30	case	case	NOUN
admet-505	705	31	of	of	ADP
admet-505	705	32	the	the	DET
admet-505	705	33	api	api	NOUN
admet-505	705	34	,	,	PUNCT
admet-505	705	35	are	be	AUX
admet-505	705	36	computational	computational	ADJ
admet-505	705	37	“	"	PUNCT
admet-505	705	38	virtual	virtual	ADJ
admet-505	705	39	”	"	PUNCT
admet-505	705	40	concentrations	concentration	NOUN
admet-505	705	41	of	of	ADP
admet-505	705	42	solid	solid	ADJ
admet-505	705	43	,	,	PUNCT
admet-505	705	44	a	a	DET
admet-505	705	45	tracking	tracking	NOUN
admet-505	705	46	tool	tool	NOUN
admet-505	705	47	designed	design	VERB
admet-505	705	48	to	to	PART
admet-505	705	49	anticipate	anticipate	VERB
admet-505	705	50	the	the	DET
admet-505	705	51	approach	approach	NOUN
admet-505	705	52	to	to	ADP
admet-505	705	53	the	the	DET
admet-505	705	54	onset	onset	NOUN
admet-505	705	55	of	of	ADP
admet-505	705	56	a	a	DET
admet-505	705	57	new	new	ADJ
admet-505	705	58	precipitate	precipitate	NOUN
admet-505	705	59	(	(	PUNCT
admet-505	705	60	as	as	SCONJ
admet-505	705	61	log	log	NOUN
admet-505	705	62	c	c	NOUN
admet-505	705	63	ascends	ascend	VERB
admet-505	705	64	to	to	ADP
admet-505	705	65	0	0	NUM
admet-505	705	66	)	)	PUNCT
admet-505	705	67	,	,	PUNCT
admet-505	705	68	or	or	CCONJ
admet-505	705	69	the	the	DET
admet-505	705	70	complete	complete	ADJ
admet-505	705	71	dissolution	dissolution	NOUN
admet-505	705	72	of	of	ADP
admet-505	705	73	a	a	DET
admet-505	705	74	solid	solid	ADJ
admet-505	705	75	(	(	PUNCT
admet-505	705	76	as	as	SCONJ
admet-505	705	77	the	the	DET
admet-505	705	78	virtual	virtual	ADJ
admet-505	705	79	log	log	NOUN
admet-505	705	80	c	c	NOUN
admet-505	705	81	descends	descend	VERB
admet-505	705	82	from	from	ADP
admet-505	705	83	0	0	NUM
admet-505	705	84	)	)	PUNCT
admet-505	705	85	admet	admet	PROPN
admet-505	705	86	&	&	CCONJ
admet-505	705	87	dmpk	dmpk	PROPN
admet-505	705	88	6(2	6(2	NUM
admet-505	705	89	)	)	PUNCT
admet-505	705	90	(	(	PUNCT
admet-505	705	91	2018	2018	NUM
admet-505	705	92	)	)	PUNCT
admet-505	705	93	105	105	NUM
admet-505	705	94	-	-	SYM
admet-505	705	95	139	139	NUM
admet-505	705	96	cocrystal	cocrystal	ADJ
admet-505	705	97	solubility	solubility	NOUN
admet-505	705	98	-	-	PUNCT
admet-505	705	99	ph	ph	VERB
admet-505	705	100	,	,	PUNCT
admet-505	705	101	drug	drug	NOUN
admet-505	705	102	solubilization	solubilization	NOUN
admet-505	705	103	capacity	capacity	NOUN
admet-505	705	104	of	of	ADP
admet-505	705	105	sds	sds	PROPN
admet-505	705	106	,	,	PUNCT
admet-505	705	107	mass	mass	ADJ
admet-505	705	108	action	action	NOUN
admet-505	705	109	model	model	NOUN
admet-505	705	110	doi	doi	PROPN
admet-505	705	111	:	:	PUNCT
admet-505	705	112	10.5599	10.5599	NUM
admet-505	705	113	/	/	SYM
admet-505	705	114	admet.505	admet.505	PROPN
admet-505	705	115	131	131	NUM
admet-505	705	116	figure	figure	NOUN
admet-505	705	117	12	12	NUM
admet-505	705	118	.	.	PUNCT
admet-505	706	1	hypothetical	hypothetical	ADJ
admet-505	706	2	atazanavir	atazanavir	PROPN
admet-505	706	3	:	:	PUNCT
admet-505	706	4	pterostilbene	pterostilbene	NOUN
admet-505	706	5	1:1	1:1	NUM
admet-505	706	6	cocrystal	cocrystal	ADJ
admet-505	706	7	system	system	NOUN
admet-505	706	8	simulated	simulate	VERB
admet-505	706	9	in	in	ADP
admet-505	706	10	the	the	DET
admet-505	706	11	study	study	NOUN
admet-505	706	12	,	,	PUNCT
admet-505	706	13	where	where	SCONJ
admet-505	706	14	100	100	NUM
admet-505	706	15	mg	mg	NUM
admet-505	706	16	/	/	SYM
admet-505	706	17	ml	ml	NOUN
admet-505	706	18	cocrystal	cocrystal	PROPN
admet-505	706	19	are	be	AUX
admet-505	706	20	added	add	VERB
admet-505	706	21	to	to	ADP
admet-505	706	22	an	an	DET
admet-505	706	23	aqueous	aqueous	ADJ
admet-505	706	24	solution	solution	NOUN
admet-505	706	25	containing	contain	VERB
admet-505	706	26	0	0	NUM
admet-505	706	27	,	,	PUNCT
admet-505	706	28	10	10	NUM
admet-505	706	29	,	,	PUNCT
admet-505	706	30	and	and	CCONJ
admet-505	706	31	20	20	NUM
admet-505	706	32	mm	mm	PROPN
admet-505	706	33	sds	sds	PROPN
admet-505	706	34	.	.	PUNCT
admet-505	707	1	the	the	DET
admet-505	707	2	symbols	symbol	NOUN
admet-505	707	3	and	and	CCONJ
admet-505	707	4	curves	curve	NOUN
admet-505	707	5	are	be	AUX
admet-505	707	6	defined	define	VERB
admet-505	707	7	in	in	ADP
admet-505	707	8	figure	figure	NOUN
admet-505	707	9	11	11	NUM
admet-505	707	10	.	.	PUNCT
admet-505	708	1	the	the	DET
admet-505	708	2	upper	upper	ADJ
admet-505	708	3	thin	thin	ADJ
admet-505	708	4	blue	blue	ADJ
admet-505	708	5	dashed	dash	VERB
admet-505	708	6	curve	curve	NOUN
admet-505	708	7	refers	refer	VERB
admet-505	708	8	to	to	ADP
admet-505	708	9	the	the	DET
admet-505	708	10	log	log	NOUN
admet-505	708	11	s	s	NOUN
admet-505	708	12	-	-	PUNCT
admet-505	708	13	ph	ph	ADJ
admet-505	708	14	profile	profile	NOUN
admet-505	708	15	expected	expect	VERB
admet-505	708	16	of	of	ADP
admet-505	708	17	pterostilbene	pterostilbene	NOUN
admet-505	708	18	in	in	ADP
admet-505	708	19	absence	absence	NOUN
admet-505	708	20	of	of	ADP
admet-505	708	21	the	the	DET
admet-505	708	22	api	api	NOUN
admet-505	708	23	,	,	PUNCT
admet-505	708	24	and	and	CCONJ
admet-505	708	25	is	be	AUX
admet-505	708	26	calculated	calculate	VERB
admet-505	708	27	using	use	VERB
admet-505	708	28	the	the	DET
admet-505	708	29	henderson	henderson	PROPN
admet-505	708	30	-	-	PUNCT
admet-505	708	31	hasselbalch	hasselbalch	PROPN
admet-505	708	32	equation	equation	NOUN
admet-505	708	33	.	.	PUNCT
admet-505	709	1	the	the	DET
admet-505	709	2	lower	low	ADJ
admet-505	709	3	thin	thin	ADJ
admet-505	709	4	red	red	ADJ
admet-505	709	5	dashed	dash	VERB
admet-505	709	6	curve	curve	NOUN
admet-505	709	7	refers	refer	VERB
admet-505	709	8	to	to	ADP
admet-505	709	9	the	the	DET
admet-505	709	10	log	log	NOUN
admet-505	709	11	s	s	NOUN
admet-505	709	12	-	-	PUNCT
admet-505	709	13	ph	ph	ADJ
admet-505	709	14	profile	profile	NOUN
admet-505	709	15	expected	expect	VERB
admet-505	709	16	of	of	ADP
admet-505	709	17	atazanavir	atazanavir	PROPN
admet-505	709	18	in	in	ADP
admet-505	709	19	absence	absence	NOUN
admet-505	709	20	of	of	ADP
admet-505	709	21	the	the	DET
admet-505	709	22	coformer	coformer	NOUN
admet-505	709	23	.	.	PUNCT
admet-505	710	1	figure	figure	NOUN
admet-505	710	2	13	13	NUM
admet-505	710	3	.	.	PUNCT
admet-505	711	1	hypothetical	hypothetical	ADJ
admet-505	711	2	atazanavir	atazanavir	PROPN
admet-505	711	3	:	:	PUNCT
admet-505	711	4	pterostilbene	pterostilbene	NOUN
admet-505	711	5	1:1	1:1	NUM
admet-505	711	6	cocrystal	cocrystal	ADJ
admet-505	711	7	system	system	NOUN
admet-505	711	8	simulated	simulate	VERB
admet-505	711	9	in	in	ADP
admet-505	711	10	the	the	DET
admet-505	711	11	study	study	NOUN
admet-505	711	12	,	,	PUNCT
admet-505	711	13	the	the	DET
admet-505	711	14	same	same	ADJ
admet-505	711	15	system	system	NOUN
admet-505	711	16	as	as	ADP
admet-505	711	17	in	in	ADP
admet-505	711	18	figure	figure	NOUN
admet-505	711	19	12	12	NUM
admet-505	711	20	,	,	PUNCT
admet-505	711	21	except	except	SCONJ
admet-505	711	22	that	that	SCONJ
admet-505	711	23	100	100	NUM
admet-505	711	24	mg	mg	NUM
admet-505	711	25	/	/	SYM
admet-505	711	26	ml	ml	NOUN
admet-505	711	27	cocrystal	cocrystal	ADJ
admet-505	711	28	plus	plus	CCONJ
admet-505	711	29	50	50	NUM
admet-505	711	30	mg	mg	NUM
admet-505	711	31	/	/	SYM
admet-505	711	32	ml	ml	PROPN
admet-505	711	33	atazanavir	atazanavir	PROPN
admet-505	711	34	are	be	AUX
admet-505	711	35	added	add	VERB
admet-505	711	36	to	to	ADP
admet-505	711	37	aqueous	aqueous	ADJ
admet-505	711	38	solutions	solution	NOUN
admet-505	711	39	containing	contain	VERB
admet-505	711	40	0	0	NUM
admet-505	711	41	,	,	PUNCT
admet-505	711	42	10	10	NUM
admet-505	711	43	,	,	PUNCT
admet-505	711	44	and	and	CCONJ
admet-505	711	45	20	20	NUM
admet-505	711	46	mm	mm	PROPN
admet-505	711	47	sds	sds	PROPN
admet-505	711	48	.	.	PUNCT
admet-505	712	1	alex	alex	PROPN
admet-505	712	2	avdeef	avdeef	PROPN
admet-505	712	3	admet	admet	PROPN
admet-505	712	4	&	&	CCONJ
admet-505	712	5	dmpk	dmpk	PROPN
admet-505	712	6	6(2	6(2	NUM
admet-505	712	7	)	)	PUNCT
admet-505	712	8	(	(	PUNCT
admet-505	712	9	2018	2018	NUM
admet-505	712	10	)	)	PUNCT
admet-505	712	11	105	105	NUM
admet-505	712	12	-	-	SYM
admet-505	712	13	139	139	NUM
admet-505	712	14	132	132	NUM
admet-505	712	15	summary	summary	NOUN
admet-505	712	16	this	this	DET
admet-505	712	17	review	review	NOUN
admet-505	712	18	considered	consider	VERB
admet-505	712	19	the	the	DET
admet-505	712	20	uses	use	NOUN
admet-505	712	21	of	of	ADP
admet-505	712	22	the	the	DET
admet-505	712	23	anionic	anionic	ADJ
admet-505	712	24	surfactant	surfactant	NOUN
admet-505	712	25	,	,	PUNCT
admet-505	712	26	sodium	sodium	NOUN
admet-505	712	27	dodecyl	dodecyl	NOUN
admet-505	712	28	sulfate	sulfate	NOUN
admet-505	712	29	(	(	PUNCT
admet-505	712	30	sds	sds	PROPN
admet-505	712	31	)	)	PUNCT
admet-505	712	32	,	,	PUNCT
admet-505	712	33	to	to	PART
admet-505	712	34	mitigate	mitigate	VERB
admet-505	712	35	poor	poor	ADJ
admet-505	712	36	bioavailability	bioavailability	NOUN
admet-505	712	37	of	of	ADP
admet-505	712	38	some	some	DET
admet-505	712	39	drugs	drug	NOUN
admet-505	712	40	due	due	ADP
admet-505	712	41	to	to	ADP
admet-505	712	42	their	their	PRON
admet-505	712	43	low	low	ADJ
admet-505	712	44	aqueous	aqueous	ADJ
admet-505	712	45	solubility	solubility	NOUN
admet-505	712	46	.	.	PUNCT
admet-505	713	1	a	a	DET
admet-505	713	2	small	small	ADJ
admet-505	713	3	database	database	NOUN
admet-505	713	4	of	of	ADP
admet-505	713	5	101	101	NUM
admet-505	713	6	drug	drug	NOUN
admet-505	713	7	solubilizing	solubilize	VERB
admet-505	713	8	capacity	capacity	NOUN
admet-505	713	9	(	(	PUNCT
admet-505	713	10	k	k	NOUN
admet-505	713	11	)	)	PUNCT
admet-505	713	12	values	value	NOUN
admet-505	713	13	was	be	AUX
admet-505	713	14	compiled	compile	VERB
admet-505	713	15	from	from	ADP
admet-505	713	16	published	publish	VERB
admet-505	713	17	sources	source	NOUN
admet-505	713	18	,	,	PUNCT
admet-505	713	19	from	from	ADP
admet-505	713	20	which	which	PRON
admet-505	713	21	a	a	DET
admet-505	713	22	k	k	PROPN
admet-505	713	23	predictive	predictive	ADJ
admet-505	713	24	model	model	NOUN
admet-505	713	25	was	be	AUX
admet-505	713	26	derived	derive	VERB
admet-505	713	27	.	.	PUNCT
admet-505	714	1	the	the	DET
admet-505	714	2	mass	mass	ADJ
admet-505	714	3	action	action	NOUN
admet-505	714	4	paradigm	paradigm	NOUN
admet-505	714	5	was	be	AUX
admet-505	714	6	used	use	VERB
admet-505	714	7	to	to	PART
admet-505	714	8	describe	describe	VERB
admet-505	714	9	drug	drug	NOUN
admet-505	714	10	-	-	PUNCT
admet-505	714	11	micelle	micelle	NOUN
admet-505	714	12	equilibrium	equilibrium	NOUN
admet-505	714	13	reactions	reaction	NOUN
admet-505	714	14	in	in	ADP
admet-505	714	15	aqueous	aqueous	ADJ
admet-505	714	16	-	-	PUNCT
admet-505	714	17	micellar	micellar	NOUN
admet-505	714	18	-	-	PUNCT
admet-505	714	19	solid	solid	ADJ
admet-505	714	20	media	medium	NOUN
admet-505	714	21	,	,	PUNCT
admet-505	714	22	as	as	ADP
admet-505	714	23	a	a	DET
admet-505	714	24	function	function	NOUN
admet-505	714	25	of	of	ADP
admet-505	714	26	ph	ph	ADJ
admet-505	714	27	,	,	PUNCT
admet-505	714	28	ionic	ionic	ADJ
admet-505	714	29	strength	strength	NOUN
admet-505	714	30	,	,	PUNCT
admet-505	714	31	and	and	CCONJ
admet-505	714	32	quantities	quantity	NOUN
admet-505	714	33	of	of	ADP
admet-505	714	34	reactants	reactant	NOUN
admet-505	714	35	used	use	VERB
admet-505	714	36	.	.	PUNCT
admet-505	715	1	the	the	DET
admet-505	715	2	k	k	PROPN
admet-505	715	3	values	value	NOUN
admet-505	715	4	were	be	AUX
admet-505	715	5	converted	convert	VERB
admet-505	715	6	to	to	ADP
admet-505	715	7	drug	drug	NOUN
admet-505	715	8	-	-	PUNCT
admet-505	715	9	micelle	micelle	NOUN
admet-505	715	10	stoichiometric	stoichiometric	ADJ
admet-505	715	11	binding	binding	ADJ
admet-505	715	12	constants	constant	NOUN
admet-505	715	13	,	,	PUNCT
admet-505	715	14	kn	kn	PROPN
admet-505	715	15	,	,	PUNCT
admet-505	715	16	corresponding	correspond	VERB
admet-505	715	17	to	to	ADP
admet-505	715	18	drug	drug	NOUN
admet-505	715	19	-	-	PUNCT
admet-505	715	20	micelle	micelle	NOUN
admet-505	715	21	equilibria	equilibrium	NOUN
admet-505	715	22	in	in	ADP
admet-505	715	23	drug	drug	NOUN
admet-505	715	24	-	-	PUNCT
admet-505	715	25	saturated	saturate	VERB
admet-505	715	26	solutions	solution	NOUN
admet-505	715	27	,	,	PUNCT
admet-505	715	28	with	with	ADP
admet-505	715	29	n	n	ADP
admet-505	715	30	values	value	NOUN
admet-505	715	31	(	(	PUNCT
admet-505	715	32	table	table	NOUN
admet-505	715	33	1	1	NUM
admet-505	715	34	)	)	PUNCT
admet-505	715	35	ranging	range	VERB
admet-505	715	36	from	from	ADP
admet-505	715	37	1	1	NUM
admet-505	715	38	(	(	PUNCT
admet-505	715	39	e.g.	e.g.	ADV
admet-505	715	40	,	,	PUNCT
admet-505	715	41	practically	practically	ADV
admet-505	715	42	-	-	PUNCT
admet-505	715	43	insoluble	insoluble	ADJ
admet-505	715	44	drugs	drug	NOUN
admet-505	715	45	:	:	PUNCT
admet-505	715	46	atazanavir	atazanavir	PROPN
admet-505	715	47	,	,	PUNCT
admet-505	715	48	clofazimine	clofazimine	ADJ
admet-505	715	49	,	,	PUNCT
admet-505	715	50	glibenclamide	glibenclamide	NOUN
admet-505	715	51	,	,	PUNCT
admet-505	715	52	mefenamic	mefenamic	ADJ
admet-505	715	53	acid	acid	NOUN
admet-505	715	54	)	)	PUNCT
admet-505	715	55	to	to	ADP
admet-505	715	56	over	over	ADP
admet-505	715	57	50	50	NUM
admet-505	715	58	(	(	PUNCT
admet-505	715	59	e.g.	e.g.	ADV
admet-505	715	60	,	,	PUNCT
admet-505	715	61	small	small	ADJ
admet-505	715	62	substituted	substitute	VERB
admet-505	715	63	benzoic	benzoic	NOUN
admet-505	715	64	acids	acid	NOUN
admet-505	715	65	,	,	PUNCT
admet-505	715	66	ketoprofen	ketoprofen	VERB
admet-505	715	67	,	,	PUNCT
admet-505	715	68	3	3	NUM
admet-505	715	69	-	-	PUNCT
admet-505	715	70	toluic	toluic	NOUN
admet-505	715	71	acid	acid	NOUN
admet-505	715	72	)	)	PUNCT
admet-505	715	73	.	.	PUNCT
admet-505	716	1	the	the	DET
admet-505	716	2	kn	kn	PROPN
admet-505	716	3	values	value	NOUN
admet-505	716	4	were	be	AUX
admet-505	716	5	further	far	ADV
admet-505	716	6	refined	refine	VERB
admet-505	716	7	by	by	ADP
admet-505	716	8	generalized	generalized	ADJ
admet-505	716	9	regression	regression	NOUN
admet-505	716	10	analysis	analysis	NOUN
admet-505	716	11	in	in	ADP
admet-505	716	12	select	select	ADJ
admet-505	716	13	cases	case	NOUN
admet-505	716	14	.	.	PUNCT
admet-505	717	1	in	in	ADP
admet-505	717	2	the	the	DET
admet-505	717	3	absence	absence	NOUN
admet-505	717	4	of	of	ADP
admet-505	717	5	drug	drug	NOUN
admet-505	717	6	,	,	PUNCT
admet-505	717	7	the	the	DET
admet-505	717	8	monomer	monomer	NOUN
admet-505	717	9	-	-	PUNCT
admet-505	717	10	micelle	micelle	NOUN
admet-505	717	11	cumulative	cumulative	ADJ
admet-505	717	12	equilibrium	equilibrium	NOUN
admet-505	717	13	,	,	PUNCT
admet-505	717	14	62	62	NUM
admet-505	717	15	sds+	sds+	SYM
admet-505	717	16	50	50	NUM
admet-505	717	17	na+	na+	NOUN
admet-505	717	18			PUNCT
admet-505	717	19	sds62na50	sds62na50	ADJ
admet-505	717	20	12-	12-	ADV
admet-505	717	21	,	,	PUNCT
admet-505	717	22	was	be	AUX
admet-505	717	23	consistent	consistent	ADJ
admet-505	717	24	with	with	ADP
admet-505	717	25	the	the	DET
admet-505	717	26	critical	critical	ADJ
admet-505	717	27	micelle	micelle	NOUN
admet-505	717	28	concentration	concentration	NOUN
admet-505	717	29	(	(	PUNCT
admet-505	717	30	cmc	cmc	NOUN
admet-505	717	31	)	)	PUNCT
admet-505	717	32	of	of	ADP
admet-505	717	33	8.3	8.3	NUM
admet-505	717	34	mm	mm	NOUN
admet-505	717	35	for	for	ADP
admet-505	717	36	the	the	DET
admet-505	717	37	aggregation	aggregation	NOUN
admet-505	717	38	constant	constant	ADJ
admet-505	717	39	log	log	NOUN
admet-505	717	40	ksds	ksds	NOUN
admet-505	717	41	=	=	NOUN
admet-505	718	1	230.6	230.6	NUM
admet-505	718	2	.	.	PUNCT
admet-505	719	1	also	also	ADV
admet-505	719	2	,	,	PUNCT
admet-505	719	3	this	this	DET
admet-505	719	4	constant	constant	ADJ
admet-505	719	5	correctly	correctly	ADV
admet-505	719	6	predicted	predict	VERB
admet-505	719	7	the	the	DET
admet-505	719	8	cmc	cmc	NOUN
admet-505	719	9	values	value	NOUN
admet-505	719	10	as	as	ADP
admet-505	719	11	a	a	DET
admet-505	719	12	function	function	NOUN
admet-505	719	13	of	of	ADP
admet-505	719	14	added	add	VERB
admet-505	719	15	nacl	nacl	NOUN
admet-505	719	16	.	.	PUNCT
admet-505	720	1	the	the	DET
admet-505	720	2	effect	effect	NOUN
admet-505	720	3	of	of	ADP
admet-505	720	4	drug	drug	NOUN
admet-505	720	5	on	on	ADP
admet-505	720	6	the	the	DET
admet-505	720	7	above	above	ADJ
admet-505	720	8	equilibrium	equilibrium	NOUN
admet-505	720	9	was	be	AUX
admet-505	720	10	considered	consider	VERB
admet-505	720	11	in	in	ADP
admet-505	720	12	select	select	ADJ
admet-505	720	13	cases	case	NOUN
admet-505	720	14	.	.	PUNCT
admet-505	721	1	an	an	DET
admet-505	721	2	in	in	ADP
admet-505	721	3	-	-	PUNCT
admet-505	721	4	depth	depth	NOUN
admet-505	721	5	case	case	NOUN
admet-505	721	6	study	study	NOUN
admet-505	721	7	of	of	ADP
admet-505	721	8	the	the	DET
admet-505	721	9	weak	weak	ADJ
admet-505	721	10	base	base	NOUN
admet-505	721	11	,	,	PUNCT
admet-505	721	12	pg-300995	pg-300995	PROPN
admet-505	721	13	[	[	X
admet-505	721	14	24	24	NUM
admet-505	721	15	,	,	PUNCT
admet-505	721	16	49	49	NUM
admet-505	721	17	,	,	PUNCT
admet-505	721	18	60	60	NUM
admet-505	721	19	]	]	PUNCT
admet-505	721	20	,	,	PUNCT
admet-505	721	21	considered	consider	VERB
admet-505	721	22	the	the	DET
admet-505	721	23	micellization	micellization	NOUN
admet-505	721	24	reactions	reaction	NOUN
admet-505	721	25	as	as	ADP
admet-505	721	26	a	a	DET
admet-505	721	27	function	function	NOUN
admet-505	721	28	of	of	ADP
admet-505	721	29	ph	ph	PROPN
admet-505	721	30	.	.	PROPN
admet-505	721	31	at	at	ADP
admet-505	721	32	ph	ph	PROPN
admet-505	721	33	1	1	NUM
admet-505	721	34	the	the	DET
admet-505	721	35	drug	drug	NOUN
admet-505	721	36	-	-	PUNCT
admet-505	721	37	sds	sds	NOUN
admet-505	721	38	salt	salt	NOUN
admet-505	721	39	was	be	AUX
admet-505	721	40	predicted	predict	VERB
admet-505	721	41	to	to	PART
admet-505	721	42	precipitate	precipitate	VERB
admet-505	721	43	both	both	PRON
admet-505	721	44	below	below	ADP
admet-505	721	45	and	and	CCONJ
admet-505	721	46	above	above	ADP
admet-505	721	47	the	the	DET
admet-505	721	48	cmc	cmc	NOUN
admet-505	721	49	.	.	PUNCT
admet-505	722	1	at	at	ADP
admet-505	722	2	very	very	ADV
admet-505	722	3	low	low	ADJ
admet-505	722	4	sds	sds	NOUN
admet-505	722	5	concentrations	concentration	NOUN
admet-505	722	6	,	,	PUNCT
admet-505	722	7	the	the	DET
admet-505	722	8	chloride	chloride	NOUN
admet-505	722	9	salt	salt	NOUN
admet-505	722	10	was	be	AUX
admet-505	722	11	predicted	predict	VERB
admet-505	722	12	to	to	AUX
admet-505	722	13	co	co	VERB
admet-505	722	14	-	-	VERB
admet-505	722	15	precipitate	precipitate	ADJ
admet-505	722	16	with	with	ADP
admet-505	722	17	the	the	DET
admet-505	722	18	drug	drug	NOUN
admet-505	722	19	-	-	PUNCT
admet-505	722	20	sds	sds	NOUN
admet-505	722	21	salt	salt	NOUN
admet-505	722	22	.	.	PUNCT
admet-505	723	1	both	both	DET
admet-505	723	2	solubility	solubility	NOUN
admet-505	723	3	products	product	NOUN
admet-505	723	4	were	be	AUX
admet-505	723	5	determined	determine	VERB
admet-505	723	6	in	in	ADP
admet-505	723	7	the	the	DET
admet-505	723	8	analysis	analysis	NOUN
admet-505	723	9	of	of	ADP
admet-505	723	10	the	the	DET
admet-505	723	11	reported	report	VERB
admet-505	723	12	solubilitysurfactant	solubilitysurfactant	ADJ
admet-505	723	13	data	datum	NOUN
admet-505	723	14	.	.	PUNCT
admet-505	724	1	above	above	ADP
admet-505	724	2	the	the	DET
admet-505	724	3	cmc	cmc	NOUN
admet-505	724	4	,	,	PUNCT
admet-505	724	5	in	in	ADP
admet-505	724	6	a	a	DET
admet-505	724	7	rare	rare	ADJ
admet-505	724	8	example	example	NOUN
admet-505	724	9	,	,	PUNCT
admet-505	724	10	the	the	DET
admet-505	724	11	charged	charge	VERB
admet-505	724	12	form	form	NOUN
admet-505	724	13	of	of	ADP
admet-505	724	14	the	the	DET
admet-505	724	15	drug	drug	NOUN
admet-505	724	16	was	be	AUX
admet-505	724	17	strongly	strongly	ADV
admet-505	724	18	solubilized	solubilize	VERB
admet-505	724	19	:	:	PUNCT
admet-505	724	20	4	4	NUM
admet-505	724	21	bh+	bh+	NOUN
admet-505	724	22	+	+	CCONJ
admet-505	724	23	sds62na50	sds62na50	ADJ
admet-505	724	24	12	12	PROPN
admet-505	724	25	(	(	PUNCT
admet-505	724	26	bh)4sds62na50	bh)4sds62na50	NOUN
admet-505	724	27	8-	8-	PROPN
admet-505	724	28	,	,	PUNCT
admet-505	724	29	with	with	ADP
admet-505	724	30	the	the	DET
admet-505	724	31	estimated	estimate	VERB
admet-505	724	32	binding	bind	VERB
admet-505	724	33	constant	constant	ADJ
admet-505	724	34	,	,	PUNCT
admet-505	724	35	log	log	NOUN
admet-505	724	36	kn	kn	PROPN
admet-505	724	37	=	=	PROPN
admet-505	724	38	23.0	23.0	NUM
admet-505	724	39	.	.	PUNCT
admet-505	725	1	at	at	ADP
admet-505	725	2	ph	ph	PROPN
admet-505	725	3	7	7	NUM
admet-505	725	4	,	,	PUNCT
admet-505	725	5	only	only	ADV
admet-505	725	6	the	the	DET
admet-505	725	7	neutral	neutral	ADJ
admet-505	725	8	form	form	NOUN
admet-505	725	9	of	of	ADP
admet-505	725	10	the	the	DET
admet-505	725	11	drug	drug	NOUN
admet-505	725	12	was	be	AUX
admet-505	725	13	solubilized	solubilize	VERB
admet-505	725	14	,	,	PUNCT
admet-505	725	15	with	with	ADP
admet-505	725	16	log	log	PROPN
admet-505	725	17	kn	kn	PROPN
admet-505	726	1	=	=	NOUN
admet-505	726	2	7.4	7.4	NUM
admet-505	726	3	(	(	PUNCT
admet-505	726	4	n=2	n=2	ADV
admet-505	726	5	)	)	PUNCT
admet-505	726	6	.	.	PUNCT
admet-505	727	1	also	also	ADV
admet-505	727	2	considered	consider	VERB
admet-505	727	3	were	be	AUX
admet-505	727	4	examples	example	NOUN
admet-505	727	5	of	of	ADP
admet-505	727	6	solubilization	solubilization	NOUN
admet-505	727	7	of	of	ADP
admet-505	727	8	solids	solid	NOUN
admet-505	727	9	in	in	ADP
admet-505	727	10	the	the	DET
admet-505	727	11	form	form	NOUN
admet-505	727	12	of	of	ADP
admet-505	727	13	cocrystals	cocrystal	NOUN
admet-505	727	14	.	.	PUNCT
admet-505	728	1	the	the	DET
admet-505	728	2	case	case	NOUN
admet-505	728	3	studies	study	NOUN
admet-505	728	4	included	include	VERB
admet-505	728	5	the	the	DET
admet-505	728	6	carbamazepine	carbamazepine	NOUN
admet-505	728	7	:	:	PUNCT
admet-505	728	8	saccharin	saccharin	NOUN
admet-505	728	9	system	system	NOUN
admet-505	728	10	,	,	PUNCT
admet-505	728	11	whose	whose	DET
admet-505	728	12	experimental	experimental	ADJ
admet-505	728	13	data	datum	NOUN
admet-505	728	14	were	be	AUX
admet-505	728	15	analyzed	analyze	VERB
admet-505	728	16	to	to	PART
admet-505	728	17	determine	determine	VERB
admet-505	728	18	the	the	DET
admet-505	728	19	binding	bind	VERB
admet-505	728	20	constants	constant	NOUN
admet-505	728	21	.	.	PUNCT
admet-505	729	1	a	a	DET
admet-505	729	2	recently	recently	ADV
admet-505	729	3	-	-	PUNCT
admet-505	729	4	described	describe	VERB
admet-505	729	5	method	method	NOUN
admet-505	729	6	for	for	ADP
admet-505	729	7	predicting	predict	VERB
admet-505	729	8	the	the	DET
admet-505	729	9	solubility	solubility	NOUN
admet-505	729	10	product	product	NOUN
admet-505	729	11	of	of	ADP
admet-505	729	12	cocrystals	cocrystal	NOUN
admet-505	729	13	(	(	PUNCT
admet-505	729	14	coupled	couple	VERB
admet-505	729	15	with	with	ADP
admet-505	729	16	predicted	predict	VERB
admet-505	729	17	k	k	PROPN
admet-505	729	18	values	value	NOUN
admet-505	729	19	described	describe	VERB
admet-505	729	20	here	here	ADV
admet-505	729	21	)	)	PUNCT
admet-505	729	22	allowed	allow	VERB
admet-505	729	23	for	for	ADP
admet-505	729	24	simulations	simulation	NOUN
admet-505	729	25	of	of	ADP
admet-505	729	26	solubility	solubility	NOUN
admet-505	729	27	-	-	PUNCT
admet-505	729	28	ph	ph	NOUN
admet-505	729	29	speciation	speciation	NOUN
admet-505	729	30	profiles	profile	NOUN
admet-505	729	31	of	of	ADP
admet-505	729	32	cocrystal	cocrystal	ADJ
admet-505	729	33	systems	system	NOUN
admet-505	729	34	in	in	ADP
admet-505	729	35	the	the	DET
admet-505	729	36	presence	presence	NOUN
admet-505	729	37	of	of	ADP
admet-505	729	38	sds	sds	PROPN
admet-505	729	39	.	.	PUNCT
admet-505	730	1	purely	purely	ADV
admet-505	730	2	on	on	ADP
admet-505	730	3	in	in	ADP
admet-505	730	4	silico	silico	NOUN
admet-505	730	5	grounds	ground	NOUN
admet-505	730	6	,	,	PUNCT
admet-505	730	7	atazanavir	atazanavir	PROPN
admet-505	730	8	was	be	AUX
admet-505	730	9	postulated	postulate	VERB
admet-505	730	10	to	to	PART
admet-505	730	11	form	form	VERB
admet-505	730	12	a	a	DET
admet-505	730	13	cocrystal	cocrystal	NOUN
admet-505	730	14	with	with	ADP
admet-505	730	15	pterostilbene	pterostilbene	NOUN
admet-505	730	16	.	.	PUNCT
admet-505	731	1	this	this	PRON
admet-505	731	2	remains	remain	VERB
admet-505	731	3	to	to	PART
admet-505	731	4	be	be	AUX
admet-505	731	5	validated	validate	VERB
admet-505	731	6	experimentally	experimentally	ADV
admet-505	731	7	.	.	PUNCT
admet-505	732	1	data	datum	NOUN
admet-505	732	2	patterns	pattern	NOUN
admet-505	732	3	depending	depend	VERB
admet-505	732	4	on	on	ADP
admet-505	732	5	the	the	DET
admet-505	732	6	amount	amount	NOUN
admet-505	732	7	of	of	ADP
admet-505	732	8	sds	sds	PROPN
admet-505	732	9	added	add	VERB
admet-505	732	10	and	and	CCONJ
admet-505	732	11	the	the	DET
admet-505	732	12	extent	extent	NOUN
admet-505	732	13	of	of	ADP
admet-505	732	14	drug	drug	NOUN
admet-505	732	15	excess	excess	NOUN
admet-505	732	16	over	over	ADP
admet-505	732	17	the	the	DET
admet-505	732	18	cocrystal	cocrystal	ADJ
admet-505	732	19	amount	amount	NOUN
admet-505	732	20	added	add	VERB
admet-505	732	21	to	to	ADP
admet-505	732	22	solution	solution	NOUN
admet-505	732	23	were	be	AUX
admet-505	732	24	explored	explore	VERB
admet-505	732	25	in	in	ADP
admet-505	732	26	silico	silico	NOUN
admet-505	732	27	.	.	PUNCT
admet-505	733	1	conclusion	conclusion	NOUN
admet-505	733	2	the	the	DET
admet-505	733	3	main	main	ADJ
admet-505	733	4	objective	objective	NOUN
admet-505	733	5	of	of	ADP
admet-505	733	6	the	the	DET
admet-505	733	7	study	study	NOUN
admet-505	733	8	was	be	AUX
admet-505	733	9	to	to	PART
admet-505	733	10	apply	apply	VERB
admet-505	733	11	simulation	simulation	NOUN
admet-505	733	12	methods	method	NOUN
admet-505	733	13	to	to	PART
admet-505	733	14	represent	represent	VERB
admet-505	733	15	drug	drug	NOUN
admet-505	733	16	-	-	PUNCT
admet-505	733	17	micelle	micelle	NOUN
admet-505	733	18	equilibrium	equilibrium	NOUN
admet-505	733	19	reactions	reaction	NOUN
admet-505	733	20	(	(	PUNCT
admet-505	733	21	based	base	VERB
admet-505	733	22	on	on	ADP
admet-505	733	23	the	the	DET
admet-505	733	24	mass	mass	ADJ
admet-505	733	25	action	action	NOUN
admet-505	733	26	paradigm	paradigm	NOUN
admet-505	733	27	)	)	PUNCT
admet-505	733	28	,	,	PUNCT
admet-505	733	29	so	so	SCONJ
admet-505	733	30	as	as	SCONJ
admet-505	733	31	to	to	PART
admet-505	733	32	optimize	optimize	VERB
admet-505	733	33	the	the	DET
admet-505	733	34	design	design	NOUN
admet-505	733	35	of	of	ADP
admet-505	733	36	experimental	experimental	ADJ
admet-505	733	37	approaches	approach	NOUN
admet-505	733	38	used	use	VERB
admet-505	733	39	to	to	PART
admet-505	733	40	assess	assess	VERB
admet-505	733	41	drug	drug	NOUN
admet-505	733	42	solubility	solubility	NOUN
admet-505	733	43	as	as	ADP
admet-505	733	44	a	a	DET
admet-505	733	45	function	function	NOUN
admet-505	733	46	of	of	ADP
admet-505	733	47	ph	ph	NOUN
admet-505	733	48	and	and	CCONJ
admet-505	733	49	the	the	DET
admet-505	733	50	amount	amount	NOUN
admet-505	733	51	of	of	ADP
admet-505	733	52	added	add	VERB
admet-505	733	53	sodium	sodium	NOUN
admet-505	733	54	dodecyl	dodecyl	PROPN
admet-505	733	55	sulfate	sulfate	NOUN
admet-505	733	56	,	,	PUNCT
admet-505	733	57	particularly	particularly	ADV
admet-505	733	58	when	when	SCONJ
admet-505	733	59	applied	apply	VERB
admet-505	733	60	to	to	ADP
admet-505	733	61	cocrystal	cocrystal	ADJ
admet-505	733	62	formulations	formulation	NOUN
admet-505	733	63	.	.	PUNCT
admet-505	734	1	in	in	ADP
admet-505	734	2	this	this	DET
admet-505	734	3	endeavor	endeavor	NOUN
admet-505	734	4	,	,	PUNCT
admet-505	734	5	a	a	DET
admet-505	734	6	new	new	ADJ
admet-505	734	7	prediction	prediction	NOUN
admet-505	734	8	model	model	NOUN
admet-505	734	9	for	for	ADP
admet-505	734	10	the	the	DET
admet-505	734	11	drug	drug	NOUN
admet-505	734	12	solubilization	solubilization	NOUN
admet-505	734	13	capacity	capacity	NOUN
admet-505	734	14	(	(	PUNCT
admet-505	734	15	k	k	NOUN
admet-505	734	16	)	)	PUNCT
admet-505	734	17	of	of	ADP
admet-505	734	18	sodium	sodium	NOUN
admet-505	734	19	dodecyl	dodecyl	PROPN
admet-505	734	20	sulfate	sulfate	NOUN
admet-505	734	21	was	be	AUX
admet-505	734	22	described	describe	VERB
admet-505	734	23	.	.	PUNCT
admet-505	735	1	well	well	INTJ
admet-505	735	2	in	in	ADP
admet-505	735	3	advance	advance	NOUN
admet-505	735	4	of	of	ADP
admet-505	735	5	any	any	DET
admet-505	735	6	actual	actual	ADJ
admet-505	735	7	measurements	measurement	NOUN
admet-505	735	8	,	,	PUNCT
admet-505	735	9	these	these	DET
admet-505	735	10	simulations	simulation	NOUN
admet-505	735	11	can	can	AUX
admet-505	735	12	be	be	AUX
admet-505	735	13	used	use	VERB
admet-505	735	14	to	to	PART
admet-505	735	15	probe	probe	VERB
admet-505	735	16	conditions	condition	NOUN
admet-505	735	17	favorable	favorable	ADJ
admet-505	735	18	to	to	ADP
admet-505	735	19	the	the	DET
admet-505	735	20	design	design	NOUN
admet-505	735	21	of	of	ADP
admet-505	735	22	experiments	experiment	NOUN
admet-505	735	23	where	where	SCONJ
admet-505	735	24	sds	sds	PROPN
admet-505	735	25	can	can	AUX
admet-505	735	26	stabilize	stabilize	VERB
admet-505	735	27	cocrystal	cocrystal	ADJ
admet-505	735	28	suspensions	suspension	NOUN
admet-505	735	29	against	against	ADP
admet-505	735	30	drug	drug	NOUN
admet-505	735	31	precipitation	precipitation	NOUN
admet-505	735	32	over	over	ADP
admet-505	735	33	a	a	DET
admet-505	735	34	range	range	NOUN
admet-505	735	35	of	of	ADP
admet-505	735	36	ph	ph	ADJ
admet-505	735	37	values	value	NOUN
admet-505	735	38	,	,	PUNCT
admet-505	735	39	in	in	ADP
admet-505	735	40	an	an	DET
admet-505	735	41	effort	effort	NOUN
admet-505	735	42	to	to	PART
admet-505	735	43	improve	improve	VERB
admet-505	735	44	the	the	DET
admet-505	735	45	rate	rate	NOUN
admet-505	735	46	and	and	CCONJ
admet-505	735	47	extent	extent	NOUN
admet-505	735	48	of	of	ADP
admet-505	735	49	oral	oral	ADJ
admet-505	735	50	absorption	absorption	NOUN
admet-505	735	51	of	of	ADP
admet-505	735	52	the	the	DET
admet-505	735	53	drug	drug	NOUN
admet-505	735	54	.	.	PUNCT
admet-505	736	1	admet	admet	PROPN
admet-505	736	2	&	&	CCONJ
admet-505	736	3	dmpk	dmpk	PROPN
admet-505	736	4	6(2	6(2	NUM
admet-505	736	5	)	)	PUNCT
admet-505	736	6	(	(	PUNCT
admet-505	736	7	2018	2018	NUM
admet-505	736	8	)	)	PUNCT
admet-505	736	9	105	105	NUM
admet-505	736	10	-	-	SYM
admet-505	736	11	139	139	NUM
admet-505	736	12	cocrystal	cocrystal	ADJ
admet-505	736	13	solubility	solubility	NOUN
admet-505	736	14	-	-	PUNCT
admet-505	736	15	ph	ph	VERB
admet-505	736	16	,	,	PUNCT
admet-505	736	17	drug	drug	NOUN
admet-505	736	18	solubilization	solubilization	NOUN
admet-505	736	19	capacity	capacity	NOUN
admet-505	736	20	of	of	ADP
admet-505	736	21	sds	sds	PROPN
admet-505	736	22	,	,	PUNCT
admet-505	736	23	mass	mass	ADJ
admet-505	736	24	action	action	NOUN
admet-505	736	25	model	model	NOUN
admet-505	736	26	doi	doi	PROPN
admet-505	736	27	:	:	PUNCT
admet-505	736	28	10.5599	10.5599	NUM
admet-505	736	29	/	/	SYM
admet-505	736	30	admet.505	admet.505	PROPN
admet-505	736	31	133	133	NUM
admet-505	736	32	glossary	glossary	ADJ
admet-505	736	33	api	api	NOUN
admet-505	736	34	active	active	ADJ
admet-505	736	35	pharmaceutical	pharmaceutical	NOUN
admet-505	736	36	ingredient	ingredient	NOUN
admet-505	736	37	,	,	PUNCT
admet-505	736	38	i.e.	i.e.	X
admet-505	736	39	,	,	PUNCT
admet-505	736	40	the	the	DET
admet-505	736	41	‘	'	PUNCT
admet-505	736	42	drug	drug	NOUN
admet-505	736	43	’	'	PUNCT
admet-505	736	44	molecule	molecule	NOUN
admet-505	736	45	coformer	coformer	NOUN
admet-505	736	46	“	"	PUNCT
admet-505	736	47	generally	generally	ADV
admet-505	736	48	regarded	regard	VERB
admet-505	736	49	as	as	ADP
admet-505	736	50	safe	safe	ADJ
admet-505	736	51	”	"	PUNCT
admet-505	736	52	soluble	soluble	ADJ
admet-505	736	53	molecule	molecule	NOUN
admet-505	736	54	that	that	PRON
admet-505	736	55	can	can	AUX
admet-505	736	56	combine	combine	VERB
admet-505	736	57	with	with	ADP
admet-505	736	58	an	an	DET
admet-505	736	59	api	api	NOUN
admet-505	736	60	to	to	PART
admet-505	736	61	form	form	VERB
admet-505	736	62	a	a	DET
admet-505	736	63	cocrystal	cocrystal	NOUN
admet-505	737	1	[	[	X
admet-505	737	2	api0	api0	X
admet-505	737	3	]	]	X
admet-505	737	4	(	(	PUNCT
admet-505	737	5	[	[	X
admet-505	737	6	cof0	cof0	NOUN
admet-505	737	7	]	]	PUNCT
admet-505	737	8	)	)	PUNCT
admet-505	737	9	concentration	concentration	NOUN
admet-505	737	10	of	of	ADP
admet-505	737	11	the	the	DET
admet-505	737	12	neutral	neutral	ADJ
admet-505	737	13	form	form	NOUN
admet-505	737	14	of	of	ADP
admet-505	737	15	api	api	NOUN
admet-505	737	16	(	(	PUNCT
admet-505	737	17	or	or	CCONJ
admet-505	737	18	coformer	coformer	NOUN
admet-505	737	19	)	)	PUNCT
admet-505	737	20	determined	determine	VERB
admet-505	737	21	from	from	ADP
admet-505	737	22	eutectic	eutectic	ADJ
admet-505	737	23	and/or	and/or	CCONJ
admet-505	737	24	eutectoid	eutectoid	PROPN
admet-505	737	25	data	datum	NOUN
admet-505	737	26	[	[	X
admet-505	737	27	api]tot	api]tot	NOUN
admet-505	737	28	,	,	PUNCT
admet-505	737	29	eu(eo	eu(eo	PROPN
admet-505	737	30	)	)	PUNCT
admet-505	737	31	measured	measure	VERB
admet-505	737	32	equilibrium	equilibrium	NOUN
admet-505	737	33	total	total	ADJ
admet-505	737	34	aqueous	aqueous	ADJ
admet-505	737	35	concentration	concentration	NOUN
admet-505	737	36	of	of	ADP
admet-505	737	37	the	the	DET
admet-505	737	38	api	api	NOUN
admet-505	737	39	at	at	ADP
admet-505	737	40	a	a	DET
admet-505	737	41	eutectic	eutectic	ADJ
admet-505	737	42	(	(	PUNCT
admet-505	737	43	or	or	CCONJ
admet-505	737	44	eutectoid	eutectoid	AUX
admet-505	737	45	)	)	PUNCT
admet-505	737	46	point	point	NOUN
admet-505	737	47	in	in	ADP
admet-505	737	48	a	a	DET
admet-505	737	49	solution	solution	NOUN
admet-505	737	50	with	with	ADP
admet-505	737	51	a	a	DET
admet-505	737	52	particular	particular	ADJ
admet-505	737	53	ph	ph	NOUN
admet-505	737	54	;	;	PUNCT
admet-505	737	55	e.g.	e.g.	ADV
admet-505	737	56	,	,	PUNCT
admet-505	737	57	points	point	NOUN
admet-505	737	58	indicated	indicate	VERB
admet-505	737	59	as	as	ADP
admet-505	737	60	red	red	ADJ
admet-505	737	61	circles	circle	NOUN
admet-505	737	62	in	in	ADP
admet-505	737	63	figs	fig	NOUN
admet-505	737	64	.	.	PUNCT
admet-505	738	1	3	3	NUM
admet-505	738	2	-	-	SYM
admet-505	738	3	5	5	NUM
admet-505	738	4	[	[	X
admet-505	738	5	cof]tot	cof]tot	NOUN
admet-505	738	6	,	,	PUNCT
admet-505	738	7	eu(eo	eu(eo	PROPN
admet-505	738	8	)	)	PUNCT
admet-505	738	9	measured	measure	VERB
admet-505	738	10	equilibrium	equilibrium	NOUN
admet-505	738	11	total	total	ADJ
admet-505	738	12	aqueous	aqueous	ADJ
admet-505	738	13	concentration	concentration	NOUN
admet-505	738	14	of	of	ADP
admet-505	738	15	the	the	DET
admet-505	738	16	coformer	coformer	NOUN
admet-505	738	17	at	at	ADP
admet-505	738	18	a	a	DET
admet-505	738	19	eutectic	eutectic	ADJ
admet-505	738	20	(	(	PUNCT
admet-505	738	21	or	or	CCONJ
admet-505	738	22	eutectoid	eutectoid	AUX
admet-505	738	23	)	)	PUNCT
admet-505	738	24	point	point	NOUN
admet-505	738	25	with	with	ADP
admet-505	738	26	a	a	DET
admet-505	738	27	particular	particular	ADJ
admet-505	738	28	ph	ph	NOUN
admet-505	738	29	;	;	PUNCT
admet-505	738	30	e.g.	e.g.	ADV
admet-505	738	31	,	,	PUNCT
admet-505	738	32	points	point	NOUN
admet-505	738	33	indicated	indicate	VERB
admet-505	738	34	as	as	ADP
admet-505	738	35	blue	blue	ADJ
admet-505	738	36	squares	square	NOUN
admet-505	738	37	in	in	ADP
admet-505	738	38	figs	fig	NOUN
admet-505	738	39	.	.	PUNCT
admet-505	739	1	3	3	NUM
admet-505	739	2	-	-	SYM
admet-505	739	3	5	5	NUM
admet-505	739	4	eutectic	eutectic	ADJ
admet-505	739	5	(	(	PUNCT
admet-505	739	6	eu	eu	NOUN
admet-505	739	7	)	)	PUNCT
admet-505	739	8	3	3	NUM
admet-505	739	9	-	-	PUNCT
admet-505	739	10	phase	phase	NOUN
admet-505	739	11	system	system	NOUN
admet-505	739	12	comprising	comprise	VERB
admet-505	739	13	a	a	DET
admet-505	739	14	stable	stable	ADJ
admet-505	739	15	suspension	suspension	NOUN
admet-505	739	16	containing	contain	VERB
admet-505	739	17	both	both	PRON
admet-505	739	18	cc	cc	PROPN
admet-505	739	19	and	and	CCONJ
admet-505	739	20	crystalline	crystalline	PROPN
admet-505	739	21	api	api	NOUN
admet-505	739	22	(	(	PUNCT
admet-505	739	23	or	or	CCONJ
admet-505	739	24	coformer	coformer	NOUN
admet-505	739	25	)	)	PUNCT
admet-505	739	26	in	in	ADP
admet-505	739	27	contact	contact	NOUN
admet-505	739	28	with	with	ADP
admet-505	739	29	a	a	DET
admet-505	739	30	saturated	saturate	VERB
admet-505	739	31	aqueous	aqueous	ADJ
admet-505	739	32	solution	solution	NOUN
admet-505	739	33	with	with	ADP
admet-505	739	34	both	both	DET
admet-505	739	35	apiand	apiand	NOUN
admet-505	739	36	coformercontaining	coformercontaining	NOUN
admet-505	739	37	species	specie	NOUN
admet-505	739	38	at	at	ADP
admet-505	739	39	a	a	DET
admet-505	739	40	particular	particular	ADJ
admet-505	739	41	ph	ph	NOUN
admet-505	739	42	eutectoid	eutectoid	NOUN
admet-505	739	43	(	(	PUNCT
admet-505	739	44	eo	eo	NOUN
admet-505	739	45	)	)	PUNCT
admet-505	739	46	“	"	PUNCT
admet-505	739	47	sub	sub	ADJ
admet-505	739	48	-	-	ADJ
admet-505	739	49	eutectic	eutectic	ADJ
admet-505	739	50	”	"	PUNCT
admet-505	739	51	point	point	NOUN
admet-505	739	52	with	with	ADP
admet-505	739	53	thermodynamically	thermodynamically	ADV
admet-505	739	54	stable	stable	ADJ
admet-505	739	55	cc	cc	PROPN
admet-505	739	56	and	and	CCONJ
admet-505	739	57	suppressed	suppress	VERB
admet-505	739	58	api	api	NOUN
admet-505	739	59	and	and	CCONJ
admet-505	739	60	coformer	coformer	NOUN
admet-505	739	61	precipitation	precipitation	NOUN
admet-505	739	62	:	:	PUNCT
admet-505	739	63	2	2	NUM
admet-505	739	64	phase	phase	NOUN
admet-505	739	65	system	system	NOUN
admet-505	739	66	comprising	comprise	VERB
admet-505	739	67	a	a	DET
admet-505	739	68	stable	stable	ADJ
admet-505	739	69	suspension	suspension	NOUN
admet-505	739	70	containing	contain	VERB
admet-505	739	71	just	just	ADV
admet-505	739	72	the	the	DET
admet-505	739	73	cc	cc	NOUN
admet-505	739	74	in	in	ADP
admet-505	739	75	contact	contact	NOUN
admet-505	739	76	with	with	ADP
admet-505	739	77	a	a	DET
admet-505	739	78	saturated	saturate	VERB
admet-505	739	79	aqueous	aqueous	ADJ
admet-505	739	80	solution	solution	NOUN
admet-505	739	81	with	with	ADP
admet-505	739	82	both	both	DET
admet-505	739	83	apiand	apiand	NOUN
admet-505	739	84	coformer	coformer	NOUN
admet-505	739	85	-	-	PUNCT
admet-505	739	86	containing	contain	VERB
admet-505	739	87	species	specie	NOUN
admet-505	739	88	at	at	ADP
admet-505	739	89	a	a	DET
admet-505	739	90	particular	particular	ADJ
admet-505	739	91	ph	ph	NOUN
admet-505	739	92	;	;	PUNCT
admet-505	739	93	system	system	NOUN
admet-505	739	94	may	may	AUX
admet-505	739	95	form	form	VERB
admet-505	739	96	even	even	ADV
admet-505	739	97	when	when	SCONJ
admet-505	739	98	cc	cc	NOUN
admet-505	739	99	plus	plus	CCONJ
admet-505	739	100	api	api	NOUN
admet-505	739	101	/	/	SYM
admet-505	739	102	coformer	coformer	NOUN
admet-505	739	103	solids	solid	NOUN
admet-505	739	104	are	be	AUX
admet-505	739	105	added	add	VERB
admet-505	739	106	to	to	ADP
admet-505	739	107	water	water	PROPN
admet-505	739	108	sds	sds	PROPN
admet-505	739	109	(	(	PUNCT
admet-505	739	110	sls	sls	PROPN
admet-505	739	111	)	)	PUNCT
admet-505	739	112	sodium	sodium	NOUN
admet-505	739	113	dodecyl	dodecyl	PROPN
admet-505	739	114	sulfate	sulfate	NOUN
admet-505	739	115	(	(	PUNCT
admet-505	739	116	i.e.	i.e.	X
admet-505	739	117	,	,	PUNCT
admet-505	739	118	sodium	sodium	NOUN
admet-505	739	119	lauryl	lauryl	NOUN
admet-505	739	120	sulfate	sulfate	NOUN
admet-505	739	121	)	)	PUNCT
admet-505	739	122	cmc	cmc	PROPN
admet-505	739	123	critical	critical	ADJ
admet-505	739	124	micelle	micelle	NOUN
admet-505	739	125	concentration	concentration	NOUN
admet-505	739	126	nagg	nagg	VERB
admet-505	739	127	micelle	micelle	NOUN
admet-505	739	128	aggregation	aggregation	NOUN
admet-505	739	129	number	number	NOUN
admet-505	739	130	(	(	PUNCT
admet-505	739	131	62	62	NUM
admet-505	739	132	for	for	ADP
admet-505	739	133	sds	sds	PROPN
admet-505	739	134	is	be	AUX
admet-505	739	135	assumed	assume	VERB
admet-505	739	136	)	)	PUNCT
admet-505	740	1	nd	nd	ADV
admet-505	740	2	average	average	ADJ
admet-505	740	3	number	number	NOUN
admet-505	740	4	of	of	ADP
admet-505	740	5	bound	bind	VERB
admet-505	740	6	drugs	drug	NOUN
admet-505	740	7	per	per	ADP
admet-505	740	8	micelle	micelle	NOUN
admet-505	740	9	fbm	fbm	NOUN
admet-505	740	10	fraction	fraction	NOUN
admet-505	740	11	of	of	ADP
admet-505	740	12	drug	drug	NOUN
admet-505	740	13	-	-	PUNCT
admet-505	740	14	bound	bind	VERB
admet-505	740	15	micelles	micelle	NOUN
admet-505	740	16	kn	kn	PROPN
admet-505	740	17	drug	drug	NOUN
admet-505	740	18	-	-	PUNCT
admet-505	740	19	micelle	micelle	NOUN
admet-505	740	20	binding	bind	VERB
admet-505	740	21	constant	constant	ADJ
admet-505	740	22	,	,	PUNCT
admet-505	740	23	where	where	SCONJ
admet-505	740	24	n	n	NUM
admet-505	740	25	drugs	drug	NOUN
admet-505	740	26	are	be	AUX
admet-505	740	27	bound	bind	VERB
admet-505	740	28	to	to	ADP
admet-505	740	29	one	one	NUM
admet-505	740	30	micelle	micelle	NOUN
admet-505	740	31	ksds	ksds	NOUN
admet-505	741	1	micelle	micelle	PROPN
admet-505	741	2	aggregation	aggregation	NOUN
admet-505	741	3	constant	constant	ADJ
admet-505	741	4	(	(	PUNCT
admet-505	741	5	cf	cf	NOUN
admet-505	741	6	.	.	NOUN
admet-505	741	7	,	,	PUNCT
admet-505	742	1	eq	eq	NOUN
admet-505	742	2	.	.	NOUN
admet-505	742	3	1	1	NUM
admet-505	742	4	)	)	PUNCT
admet-505	742	5	s	s	VERB
admet-505	742	6	solubility	solubility	NOUN
admet-505	742	7	,	,	PUNCT
admet-505	742	8	ideally	ideally	ADV
admet-505	742	9	expressed	express	VERB
admet-505	742	10	in	in	ADP
admet-505	742	11	units	unit	NOUN
admet-505	742	12	of	of	ADP
admet-505	742	13	mol	mol	PROPN
admet-505	742	14	/	/	SYM
admet-505	742	15	l	l	NOUN
admet-505	742	16	(	(	PUNCT
admet-505	742	17	m	m	NOUN
admet-505	742	18	)	)	PUNCT
admet-505	742	19	or	or	CCONJ
admet-505	742	20	mg	mg	PROPN
admet-505	742	21	/	/	SYM
admet-505	742	22	ml	ml	ADP
admet-505	742	23	s0	s0	NOUN
admet-505	742	24	“	"	PUNCT
admet-505	742	25	intrinsic	intrinsic	ADJ
admet-505	742	26	”	"	PUNCT
admet-505	742	27	solubility	solubility	NOUN
admet-505	742	28	(	(	PUNCT
admet-505	742	29	i.e.	i.e.	X
admet-505	742	30	,	,	PUNCT
admet-505	742	31	the	the	DET
admet-505	742	32	solubility	solubility	NOUN
admet-505	742	33	of	of	ADP
admet-505	742	34	the	the	DET
admet-505	742	35	uncharged	uncharged	ADJ
admet-505	742	36	form	form	NOUN
admet-505	742	37	of	of	ADP
admet-505	742	38	the	the	DET
admet-505	742	39	compound	compound	NOUN
admet-505	742	40	)	)	PUNCT
admet-505	742	41	sw	sw	PROPN
admet-505	742	42	“	"	PUNCT
admet-505	742	43	water	water	NOUN
admet-505	742	44	”	"	PUNCT
admet-505	742	45	solubility	solubility	NOUN
admet-505	742	46	,	,	PUNCT
admet-505	742	47	defined	define	VERB
admet-505	742	48	by	by	ADP
admet-505	742	49	dissolving	dissolve	VERB
admet-505	742	50	enough	enough	ADJ
admet-505	742	51	pure	pure	ADJ
admet-505	742	52	free	free	ADJ
admet-505	742	53	acid	acid	NOUN
admet-505	742	54	/	/	SYM
admet-505	742	55	base	base	NOUN
admet-505	742	56	(	(	PUNCT
admet-505	742	57	not	not	PART
admet-505	742	58	drug	drug	NOUN
admet-505	742	59	salt	salt	NOUN
admet-505	742	60	)	)	PUNCT
admet-505	742	61	in	in	ADP
admet-505	742	62	water	water	NOUN
admet-505	742	63	(	(	PUNCT
admet-505	742	64	or	or	CCONJ
admet-505	742	65	water	water	NOUN
admet-505	742	66	containing	contain	VERB
admet-505	742	67	an	an	DET
admet-505	742	68	inert	inert	ADJ
admet-505	742	69	salt	salt	NOUN
admet-505	742	70	as	as	ADP
admet-505	742	71	ionic	ionic	ADJ
admet-505	742	72	strength	strength	NOUN
admet-505	742	73	adjustor	adjustor	NOUN
admet-505	742	74	)	)	PUNCT
admet-505	742	75	to	to	PART
admet-505	742	76	form	form	VERB
admet-505	742	77	a	a	DET
admet-505	742	78	saturated	saturate	VERB
admet-505	742	79	solution	solution	NOUN
admet-505	742	80	scc	scc	NOUN
admet-505	742	81	solubility	solubility	NOUN
admet-505	742	82	of	of	ADP
admet-505	742	83	cc	cc	PROPN
admet-505	742	84	;	;	PUNCT
admet-505	742	85	if	if	SCONJ
admet-505	742	86	a	a	DET
admet-505	742	87	eutectoid	eutectoid	ADJ
admet-505	742	88	system	system	NOUN
admet-505	742	89	forms	form	NOUN
admet-505	742	90	by	by	ADP
admet-505	742	91	adding	add	VERB
admet-505	742	92	excess	excess	ADJ
admet-505	742	93	cc	cc	NOUN
admet-505	742	94	(	(	PUNCT
admet-505	742	95	without	without	ADP
admet-505	742	96	additional	additional	ADJ
admet-505	742	97	api	api	NOUN
admet-505	742	98	or	or	CCONJ
admet-505	742	99	coformer	coformer	NOUN
admet-505	742	100	)	)	PUNCT
admet-505	742	101	to	to	ADP
admet-505	742	102	ph	ph	VERB
admet-505	742	103	-	-	PUNCT
admet-505	742	104	adjusted	adjust	VERB
admet-505	742	105	water	water	NOUN
admet-505	742	106	,	,	PUNCT
admet-505	742	107	then	then	ADV
admet-505	742	108	scc	scc	NOUN
admet-505	742	109	=	=	PUNCT
admet-505	743	1	[	[	X
admet-505	743	2	api]tot	api]tot	NOUN
admet-505	743	3	,	,	PUNCT
admet-505	743	4	eo	eo	NOUN
admet-505	744	1	=	=	PUNCT
admet-505	745	1	[	[	X
admet-505	745	2	cof]tot	cof]tot	NOUN
admet-505	745	3	,	,	PUNCT
admet-505	745	4	eo	eo	NOUN
admet-505	745	5	;	;	PUNCT
admet-505	745	6	e.g.	e.g.	ADV
admet-505	745	7	,	,	PUNCT
admet-505	745	8	curves	curve	NOUN
admet-505	745	9	indicated	indicate	VERB
admet-505	745	10	by	by	ADP
admet-505	745	11	purple	purple	ADJ
admet-505	745	12	thick	thick	ADJ
admet-505	745	13	dashed	dash	VERB
admet-505	745	14	lines	line	NOUN
admet-505	745	15	in	in	ADP
admet-505	745	16	figs	fig	NOUN
admet-505	745	17	.	.	PUNCT
admet-505	746	1	11	11	NUM
admet-505	746	2	-	-	SYM
admet-505	746	3	13	13	NUM
admet-505	746	4	.	.	PUNCT
admet-505	747	1	s0	s0	PROPN
admet-505	747	2	api	api	PROPN
admet-505	747	3	(	(	PUNCT
admet-505	747	4	s0	s0	PROPN
admet-505	747	5	cof	cof	PROPN
admet-505	747	6	)	)	PUNCT
admet-505	747	7	intrinsic	intrinsic	ADJ
admet-505	747	8	solubility	solubility	NOUN
admet-505	747	9	in	in	ADP
admet-505	747	10	a	a	DET
admet-505	747	11	non	non	ADJ
admet-505	747	12	-	-	ADJ
admet-505	747	13	cc	cc	ADJ
admet-505	747	14	2	2	NUM
admet-505	747	15	-	-	PUNCT
admet-505	747	16	phase	phase	NOUN
admet-505	747	17	system	system	NOUN
admet-505	747	18	,	,	PUNCT
admet-505	747	19	where	where	SCONJ
admet-505	747	20	the	the	DET
admet-505	747	21	crystalline	crystalline	ADJ
admet-505	747	22	api	api	NOUN
admet-505	747	23	(	(	PUNCT
admet-505	747	24	or	or	CCONJ
admet-505	747	25	coformer	coformer	NOUN
admet-505	747	26	)	)	PUNCT
admet-505	747	27	is	be	AUX
admet-505	747	28	in	in	ADP
admet-505	747	29	equilibrium	equilibrium	NOUN
admet-505	747	30	with	with	ADP
admet-505	747	31	a	a	DET
admet-505	747	32	saturated	saturate	VERB
admet-505	747	33	solution	solution	NOUN
admet-505	747	34	of	of	ADP
admet-505	747	35	the	the	DET
admet-505	747	36	neutral	neutral	ADJ
admet-505	747	37	api	api	NOUN
admet-505	747	38	(	(	PUNCT
admet-505	747	39	or	or	CCONJ
admet-505	747	40	coformer	coformer	NOUN
admet-505	747	41	)	)	PUNCT
admet-505	747	42	σα2	σα2	NOUN
admet-505	747	43	h	h	NOUN
admet-505	747	44	abraham	abraham	PROPN
admet-505	747	45	descriptor	descriptor	PROPN
admet-505	747	46	–	–	PUNCT
admet-505	747	47	solute	solute	VERB
admet-505	747	48	h	h	NOUN
admet-505	747	49	-	-	PUNCT
admet-505	747	50	bond	bond	NOUN
admet-505	747	51	total	total	ADJ
admet-505	747	52	acidity	acidity	NOUN
admet-505	747	53	(	(	PUNCT
admet-505	747	54	also	also	ADV
admet-505	747	55	called	call	VERB
admet-505	747	56	a	a	PRON
admet-505	747	57	)	)	PUNCT
admet-505	747	58	σβ2	σβ2	VERB
admet-505	747	59	h	h	PROPN
admet-505	747	60	abraham	abraham	PROPN
admet-505	747	61	descriptor	descriptor	PROPN
admet-505	747	62	–	–	PUNCT
admet-505	747	63	solute	solute	VERB
admet-505	747	64	h	h	NOUN
admet-505	747	65	-	-	PUNCT
admet-505	747	66	bond	bond	NOUN
admet-505	747	67	total	total	NOUN
admet-505	747	68	basicity	basicity	NOUN
admet-505	747	69	(	(	PUNCT
admet-505	747	70	also	also	ADV
admet-505	747	71	called	call	VERB
admet-505	747	72	b	b	NOUN
admet-505	747	73	)	)	PUNCT
admet-505	747	74	π2	π2	ADJ
admet-505	747	75	abraham	abraham	PROPN
admet-505	747	76	descriptor	descriptor	NOUN
admet-505	747	77	–	–	PUNCT
admet-505	747	78	solute	solute	VERB
admet-505	747	79	polarity	polarity	NOUN
admet-505	747	80	/	/	SYM
admet-505	747	81	polarizability	polarizability	NOUN
admet-505	747	82	due	due	ADP
admet-505	747	83	to	to	ADP
admet-505	747	84	solute	solute	VERB
admet-505	747	85	-	-	PUNCT
admet-505	747	86	solvent	solvent	ADJ
admet-505	747	87	interactions	interaction	NOUN
admet-505	747	88	between	between	ADP
admet-505	747	89	bond	bond	NOUN
admet-505	747	90	dipoles	dipole	NOUN
admet-505	747	91	and	and	CCONJ
admet-505	747	92	induced	induce	VERB
admet-505	747	93	dipoles	dipole	NOUN
admet-505	747	94	(	(	PUNCT
admet-505	747	95	also	also	ADV
admet-505	747	96	called	call	VERB
admet-505	747	97	s	s	PART
admet-505	747	98	)	)	PUNCT
admet-505	747	99	r2	r2	PROPN
admet-505	747	100	abraham	abraham	PROPN
admet-505	747	101	descriptor	descriptor	NOUN
admet-505	747	102	–	–	PUNCT
admet-505	747	103	excess	excess	ADJ
admet-505	747	104	molar	molar	ADJ
admet-505	747	105	refraction	refraction	NOUN
admet-505	747	106	(	(	PUNCT
admet-505	747	107	l·mol-1	l·mol-1	NOUN
admet-505	747	108	/	/	SYM
admet-505	747	109	10	10	NUM
admet-505	747	110	)	)	PUNCT
admet-505	747	111	;	;	PUNCT
admet-505	747	112	which	which	PRON
admet-505	747	113	models	model	VERB
admet-505	747	114	dispersion	dispersion	NOUN
admet-505	747	115	force	force	NOUN
admet-505	747	116	interaction	interaction	NOUN
admet-505	747	117	arising	arise	VERB
admet-505	747	118	from	from	ADP
admet-505	747	119	piand	piand	NOUN
admet-505	747	120	n	n	CCONJ
admet-505	747	121	-	-	PUNCT
admet-505	747	122	electrons	electron	NOUN
admet-505	747	123	of	of	ADP
admet-505	747	124	the	the	DET
admet-505	747	125	solute	solute	NOUN
admet-505	747	126	(	(	PUNCT
admet-505	747	127	also	also	ADV
admet-505	747	128	called	call	VERB
admet-505	747	129	e	e	NOUN
admet-505	747	130	)	)	PUNCT
admet-505	747	131	vx	vx	PROPN
admet-505	747	132	abraham	abraham	PROPN
admet-505	747	133	descriptor	descriptor	PROPN
admet-505	747	134	–	–	PUNCT
admet-505	747	135	mcgowan	mcgowan	PROPN
admet-505	747	136	molar	molar	PROPN
admet-505	747	137	volume	volume	NOUN
admet-505	747	138	(	(	PUNCT
admet-505	747	139	l·mol-1	l·mol-1	NOUN
admet-505	747	140	/	/	SYM
admet-505	747	141	100	100	NUM
admet-505	747	142	)	)	PUNCT
admet-505	747	143	of	of	ADP
admet-505	747	144	the	the	DET
admet-505	747	145	solute	solute	PROPN
admet-505	747	146	ia	ia	PROPN
admet-505	747	147	,	,	PUNCT
admet-505	747	148	ib	ib	PROPN
admet-505	747	149	,	,	PUNCT
admet-505	747	150	iab	iab	PROPN
admet-505	747	151	,	,	PUNCT
admet-505	747	152	in	in	ADP
admet-505	747	153	indicator	indicator	NOUN
admet-505	747	154	indices	index	NOUN
admet-505	747	155	:	:	PUNCT
admet-505	747	156	unit	unit	NOUN
admet-505	747	157	value	value	NOUN
admet-505	747	158	,	,	PUNCT
admet-505	747	159	indicating	indicate	VERB
admet-505	747	160	that	that	SCONJ
admet-505	747	161	a	a	DET
admet-505	747	162	molecule	molecule	NOUN
admet-505	747	163	is	be	AUX
admet-505	747	164	an	an	DET
admet-505	747	165	acid	acid	ADJ
admet-505	747	166	,	,	PUNCT
admet-505	747	167	base	base	NOUN
admet-505	747	168	,	,	PUNCT
admet-505	747	169	ampholyte	ampholyte	ADJ
admet-505	747	170	,	,	PUNCT
admet-505	747	171	or	or	CCONJ
admet-505	747	172	neutral	neutral	ADJ
admet-505	747	173	,	,	PUNCT
admet-505	747	174	respectively	respectively	ADV
admet-505	747	175	,	,	PUNCT
admet-505	747	176	and	and	CCONJ
admet-505	747	177	zero	zero	NUM
admet-505	747	178	otherwise	otherwise	ADV
admet-505	747	179	alex	alex	PROPN
admet-505	747	180	avdeef	avdeef	PROPN
admet-505	747	181	admet	admet	PROPN
admet-505	747	182	&	&	CCONJ
admet-505	747	183	dmpk	dmpk	PROPN
admet-505	747	184	6(2	6(2	NUM
admet-505	747	185	)	)	PUNCT
admet-505	747	186	(	(	PUNCT
admet-505	747	187	2018	2018	NUM
admet-505	747	188	)	)	PUNCT
admet-505	747	189	105	105	NUM
admet-505	747	190	-	-	SYM
admet-505	747	191	139	139	NUM
admet-505	747	192	134	134	NUM
admet-505	747	193	acknowledgements	acknowledgement	NOUN
admet-505	747	194	helpful	helpful	ADJ
admet-505	747	195	discussions	discussion	NOUN
admet-505	747	196	with	with	ADP
admet-505	747	197	profs	prof	NOUN
admet-505	747	198	.	.	PUNCT
admet-505	748	1	naír	naír	PROPN
admet-505	748	2	rodríguez	rodríguez	PROPN
admet-505	748	3	-	-	PUNCT
admet-505	748	4	hornedo	hornedo	PROPN
admet-505	748	5	(	(	PUNCT
admet-505	748	6	univ	univ	PROPN
admet-505	748	7	.	.	PROPN
admet-505	748	8	of	of	ADP
admet-505	748	9	michigan	michigan	PROPN
admet-505	748	10	,	,	PUNCT
admet-505	748	11	usa	usa	PROPN
admet-505	748	12	)	)	PUNCT
admet-505	748	13	and	and	CCONJ
admet-505	748	14	elena	elena	PROPN
admet-505	748	15	boldyreva	boldyreva	PROPN
admet-505	748	16	(	(	PUNCT
admet-505	748	17	institute	institute	PROPN
admet-505	748	18	of	of	ADP
admet-505	748	19	solid	solid	ADJ
admet-505	748	20	state	state	NOUN
admet-505	748	21	chemistry	chemistry	NOUN
admet-505	748	22	and	and	CCONJ
admet-505	748	23	mechanochemistry	mechanochemistry	NOUN
admet-505	748	24	,	,	PUNCT
admet-505	748	25	novosibirsk	novosibirsk	PROPN
admet-505	748	26	,	,	PUNCT
admet-505	748	27	russian	russian	ADJ
admet-505	748	28	federation	federation	PROPN
admet-505	748	29	)	)	PUNCT
admet-505	748	30	on	on	ADP
admet-505	748	31	the	the	DET
admet-505	748	32	topic	topic	NOUN
admet-505	748	33	of	of	ADP
admet-505	748	34	cocrystals	cocrystal	NOUN
admet-505	748	35	are	be	AUX
admet-505	748	36	much	much	ADV
admet-505	748	37	appreciated	appreciated	ADJ
admet-505	748	38	.	.	PUNCT
admet-505	749	1	references	reference	NOUN
admet-505	749	2	[	[	X
admet-505	749	3	1	1	NUM
admet-505	749	4	]	]	X
admet-505	749	5	s.r	s.r	PROPN
admet-505	749	6	.	.	PROPN
admet-505	749	7	burn	burn	PROPN
admet-505	749	8	,	,	PUNCT
admet-505	749	9	g.	g.	PROPN
admet-505	749	10	zografi	zografi	PROPN
admet-505	749	11	,	,	PUNCT
admet-505	750	1	x.s	x.s	PROPN
admet-505	750	2	.	.	PUNCT
admet-505	750	3	chen	chen	PROPN
admet-505	750	4	.	.	PUNCT
admet-505	751	1	solid	solid	ADJ
admet-505	751	2	-	-	PUNCT
admet-505	751	3	state	state	NOUN
admet-505	751	4	properties	property	NOUN
admet-505	751	5	of	of	ADP
admet-505	751	6	pharmaceutical	pharmaceutical	ADJ
admet-505	751	7	materials	material	NOUN
admet-505	751	8	.	.	PUNCT
admet-505	752	1	john	john	PROPN
admet-505	752	2	wiley	wiley	PROPN
admet-505	752	3	&	&	CCONJ
admet-505	752	4	sons	sons	PROPN
admet-505	752	5	,	,	PUNCT
admet-505	752	6	inc	inc	PROPN
admet-505	752	7	.	.	PROPN
admet-505	752	8	,	,	PUNCT
admet-505	752	9	hoboken	hoboken	PROPN
admet-505	752	10	,	,	PUNCT
admet-505	752	11	nj	nj	PROPN
admet-505	752	12	,	,	PUNCT
admet-505	752	13	2017	2017	NUM
admet-505	752	14	.	.	PUNCT
admet-505	753	1	[	[	X
admet-505	753	2	2	2	X
admet-505	753	3	]	]	X
admet-505	753	4	h.g	h.g	PROPN
admet-505	753	5	.	.	PUNCT
admet-505	753	6	brittain	brittain	PROPN
admet-505	753	7	.	.	PUNCT
admet-505	754	1	cocrystal	cocrystal	PROPN
admet-505	754	2	systems	system	NOUN
admet-505	754	3	of	of	ADP
admet-505	754	4	pharmaceutical	pharmaceutical	ADJ
admet-505	754	5	interest	interest	NOUN
admet-505	754	6	:	:	PUNCT
admet-505	754	7	2011	2011	NUM
admet-505	754	8	.	.	PUNCT
admet-505	755	1	cryst	cryst	PROPN
admet-505	755	2	growth	growth	PROPN
admet-505	755	3	des	des	PROPN
admet-505	755	4	.	.	PROPN
admet-505	755	5	12	12	NUM
admet-505	755	6	(	(	PUNCT
admet-505	755	7	2012	2012	NUM
admet-505	755	8	)	)	PUNCT
admet-505	755	9	5823	5823	NUM
admet-505	755	10	-	-	SYM
admet-505	755	11	5832	5832	NUM
admet-505	755	12	.	.	PUNCT
admet-505	756	1	[	[	X
admet-505	756	2	3	3	X
admet-505	756	3	]	]	X
admet-505	756	4	j.	j.	PROPN
admet-505	756	5	wouters	wouters	PROPN
admet-505	756	6	,	,	PUNCT
admet-505	756	7	l.	l.	PROPN
admet-505	756	8	quéré	quéré	PROPN
admet-505	756	9	(	(	PUNCT
admet-505	756	10	eds	ed	NOUN
admet-505	756	11	.	.	PUNCT
admet-505	756	12	)	)	PUNCT
admet-505	756	13	.	.	PUNCT
admet-505	757	1	pharmaceutical	pharmaceutical	NOUN
admet-505	757	2	salts	salt	NOUN
admet-505	757	3	and	and	CCONJ
admet-505	757	4	co	co	NOUN
admet-505	757	5	-	-	NOUN
admet-505	757	6	crystals	crystal	NOUN
admet-505	757	7	.	.	PUNCT
admet-505	758	1	royal	royal	ADJ
admet-505	758	2	society	society	NOUN
admet-505	758	3	of	of	ADP
admet-505	758	4	chemistry	chemistry	NOUN
admet-505	758	5	,	,	PUNCT
admet-505	758	6	cambridge	cambridge	PROPN
admet-505	758	7	,	,	PUNCT
admet-505	758	8	2012	2012	NUM
admet-505	758	9	.	.	PUNCT
admet-505	759	1	[	[	X
admet-505	759	2	4	4	X
admet-505	759	3	]	]	X
admet-505	759	4	j.w	j.w	PROPN
admet-505	759	5	.	.	PROPN
admet-505	759	6	steed	steed	PROPN
admet-505	759	7	.	.	PUNCT
admet-505	760	1	the	the	DET
admet-505	760	2	role	role	NOUN
admet-505	760	3	of	of	ADP
admet-505	760	4	co	co	NOUN
admet-505	760	5	-	-	NOUN
admet-505	760	6	crystals	crystal	NOUN
admet-505	760	7	in	in	ADP
admet-505	760	8	pharmaceutical	pharmaceutical	ADJ
admet-505	760	9	design	design	NOUN
admet-505	760	10	.	.	PUNCT
admet-505	761	1	trends	trend	NOUN
admet-505	761	2	pharm	pharm	PROPN
admet-505	761	3	sci	sci	PROPN
admet-505	761	4	.	.	PROPN
admet-505	762	1	34	34	NUM
admet-505	762	2	(	(	PUNCT
admet-505	762	3	2013	2013	NUM
admet-505	762	4	)	)	PUNCT
admet-505	762	5	185	185	NUM
admet-505	762	6	-	-	SYM
admet-505	762	7	193	193	NUM
admet-505	762	8	.	.	PUNCT
admet-505	763	1	[	[	X
admet-505	763	2	5	5	X
admet-505	763	3	]	]	X
admet-505	763	4	g.	g.	PROPN
admet-505	763	5	kuminek	kuminek	PROPN
admet-505	763	6	,	,	PUNCT
admet-505	763	7	f.	f.	PROPN
admet-505	763	8	cao	cao	PROPN
admet-505	763	9	,	,	PUNCT
admet-505	763	10	a.	a.	NOUN
admet-505	763	11	bahia	bahia	X
admet-505	763	12	de	de	PROPN
admet-505	763	13	oliveira	oliveira	PROPN
admet-505	763	14	da	da	PROPN
admet-505	763	15	rocha	rocha	PROPN
admet-505	763	16	,	,	PUNCT
admet-505	763	17	s.g	s.g	PROPN
admet-505	763	18	.	.	PROPN
admet-505	763	19	cardoso	cardoso	PROPN
admet-505	763	20	,	,	PUNCT
admet-505	763	21	n.	n.	PROPN
admet-505	763	22	rodríguez	rodríguez	PROPN
admet-505	763	23	-	-	PUNCT
admet-505	763	24	hornedo	hornedo	PROPN
admet-505	763	25	.	.	PUNCT
admet-505	764	1	cocrystals	cocrystal	NOUN
admet-505	764	2	to	to	PART
admet-505	764	3	facilitate	facilitate	VERB
admet-505	764	4	delivery	delivery	NOUN
admet-505	764	5	of	of	ADP
admet-505	764	6	poorly	poorly	ADV
admet-505	764	7	soluble	soluble	ADJ
admet-505	764	8	compounds	compound	NOUN
admet-505	764	9	beyond	beyond	ADP
admet-505	764	10	-	-	PUNCT
admet-505	764	11	rule	rule	NOUN
admet-505	764	12	-	-	PUNCT
admet-505	764	13	of-5	of-5	NUM
admet-505	764	14	.	.	PUNCT
admet-505	765	1	adv	adv	PROPN
admet-505	765	2	.	.	PUNCT
admet-505	765	3	drug	drug	PROPN
admet-505	765	4	deliv	deliv	PROPN
admet-505	765	5	.	.	PUNCT
admet-505	766	1	rev	rev	PROPN
admet-505	766	2	.	.	PROPN
admet-505	767	1	101	101	NUM
admet-505	767	2	(	(	PUNCT
admet-505	767	3	2016	2016	NUM
admet-505	767	4	)	)	PUNCT
admet-505	767	5	143166	143166	NUM
admet-505	767	6	.	.	PUNCT
admet-505	768	1	[	[	X
admet-505	768	2	6	6	NUM
admet-505	768	3	]	]	X
admet-505	768	4	n.	n.	PROPN
admet-505	768	5	huang	huang	PROPN
admet-505	768	6	,	,	PUNCT
admet-505	768	7	n.	n.	PROPN
admet-505	768	8	rodríguez	rodríguez	PROPN
admet-505	768	9	-	-	PUNCT
admet-505	768	10	hornedo	hornedo	NOUN
admet-505	768	11	.	.	PUNCT
admet-505	769	1	engineering	engineering	NOUN
admet-505	769	2	cocrystal	cocrystal	PROPN
admet-505	769	3	solubility	solubility	PROPN
admet-505	769	4	,	,	PUNCT
admet-505	769	5	stability	stability	NOUN
admet-505	769	6	,	,	PUNCT
admet-505	769	7	and	and	CCONJ
admet-505	769	8	phmax	phmax	ADV
admet-505	769	9	by	by	ADP
admet-505	769	10	micellar	micellar	ADJ
admet-505	769	11	solubilization	solubilization	NOUN
admet-505	769	12	.	.	PUNCT
admet-505	770	1	j.	j.	PROPN
admet-505	770	2	pharm	pharm	PROPN
admet-505	770	3	.	.	PUNCT
admet-505	771	1	sci	sci	PROPN
admet-505	771	2	.	.	PROPN
admet-505	771	3	100	100	NUM
admet-505	771	4	(	(	PUNCT
admet-505	771	5	2011	2011	NUM
admet-505	771	6	)	)	PUNCT
admet-505	771	7	5219	5219	NUM
admet-505	771	8	-	-	SYM
admet-505	771	9	5234	5234	NUM
admet-505	771	10	.	.	PUNCT
admet-505	772	1	[	[	X
admet-505	772	2	7	7	NUM
admet-505	772	3	]	]	X
admet-505	772	4	i.	i.	NOUN
admet-505	772	5	tomaszewska	tomaszewska	PROPN
admet-505	772	6	,	,	PUNCT
admet-505	772	7	s.	s.	PROPN
admet-505	772	8	karki	karki	PROPN
admet-505	772	9	,	,	PUNCT
admet-505	772	10	j.	j.	PROPN
admet-505	772	11	shur	shur	PROPN
admet-505	772	12	,	,	PUNCT
admet-505	772	13	r.	r.	PROPN
admet-505	772	14	price	price	PROPN
admet-505	772	15	,	,	PUNCT
admet-505	772	16	n.	n.	PROPN
admet-505	772	17	fotaki	fotaki	PROPN
admet-505	772	18	.	.	PUNCT
admet-505	772	19	pharmaceutical	pharmaceutical	ADJ
admet-505	772	20	characterisation	characterisation	NOUN
admet-505	772	21	and	and	CCONJ
admet-505	772	22	evaluation	evaluation	NOUN
admet-505	772	23	of	of	ADP
admet-505	772	24	cocrystals	cocrystal	NOUN
admet-505	772	25	:	:	PUNCT
admet-505	772	26	importance	importance	NOUN
admet-505	772	27	of	of	ADP
admet-505	772	28	in	in	ADP
admet-505	772	29	vitro	vitro	X
admet-505	772	30	dissolution	dissolution	NOUN
admet-505	772	31	conditions	condition	NOUN
admet-505	772	32	and	and	CCONJ
admet-505	772	33	type	type	NOUN
admet-505	772	34	of	of	ADP
admet-505	772	35	coformer	coformer	NOUN
admet-505	772	36	.	.	PUNCT
admet-505	773	1	int	int	NOUN
admet-505	773	2	.	.	PUNCT
admet-505	774	1	j.	j.	PROPN
admet-505	774	2	pharm	pharm	PROPN
admet-505	774	3	.	.	PUNCT
admet-505	775	1	453	453	NUM
admet-505	775	2	(	(	PUNCT
admet-505	775	3	2013	2013	NUM
admet-505	775	4	)	)	PUNCT
admet-505	775	5	380	380	NUM
admet-505	775	6	-	-	SYM
admet-505	775	7	388	388	NUM
admet-505	775	8	.	.	PUNCT
admet-505	776	1	[	[	X
admet-505	776	2	8	8	NUM
admet-505	776	3	]	]	X
admet-505	776	4	m.p	m.p	PROPN
admet-505	776	5	.	.	PROPN
admet-505	776	6	lipert	lipert	PROPN
admet-505	776	7	,	,	PUNCT
admet-505	776	8	l.	l.	PROPN
admet-505	776	9	roy	roy	PROPN
admet-505	776	10	,	,	PUNCT
admet-505	776	11	s.l	s.l	PROPN
admet-505	776	12	.	.	PROPN
admet-505	776	13	childs	childs	PROPN
admet-505	776	14	,	,	PUNCT
admet-505	776	15	n.	n.	PROPN
admet-505	776	16	rodriguez	rodriguez	PROPN
admet-505	776	17	-	-	PUNCT
admet-505	776	18	hornedo	hornedo	PROPN
admet-505	776	19	.	.	PUNCT
admet-505	777	1	cocrystal	cocrystal	ADJ
admet-505	777	2	solubilization	solubilization	NOUN
admet-505	777	3	in	in	ADP
admet-505	777	4	biorelevant	biorelevant	ADJ
admet-505	777	5	media	medium	NOUN
admet-505	777	6	and	and	CCONJ
admet-505	777	7	its	its	PRON
admet-505	777	8	prediction	prediction	NOUN
admet-505	777	9	from	from	ADP
admet-505	777	10	drug	drug	NOUN
admet-505	777	11	solubilization	solubilization	NOUN
admet-505	777	12	.	.	PUNCT
admet-505	778	1	j.	j.	PROPN
admet-505	778	2	pharm	pharm	PROPN
admet-505	778	3	.	.	PUNCT
admet-505	779	1	sci	sci	PROPN
admet-505	779	2	.	.	PROPN
admet-505	780	1	104	104	NUM
admet-505	780	2	(	(	PUNCT
admet-505	780	3	2015	2015	NUM
admet-505	780	4	)	)	PUNCT
admet-505	780	5	4153–4163	4153–4163	NUM
admet-505	780	6	.	.	PUNCT
admet-505	781	1	[	[	X
admet-505	781	2	9	9	NUM
admet-505	781	3	]	]	PUNCT
admet-505	781	4	f.	f.	PROPN
admet-505	781	5	cao	cao	PROPN
admet-505	781	6	,	,	PUNCT
admet-505	781	7	g.l	g.l	PROPN
admet-505	781	8	.	.	PROPN
admet-505	781	9	amidon	amidon	PROPN
admet-505	781	10	,	,	PUNCT
admet-505	781	11	n.	n.	PROPN
admet-505	781	12	rodríguez	rodríguez	PROPN
admet-505	781	13	-	-	PUNCT
admet-505	781	14	hornedo	hornedo	PROPN
admet-505	781	15	,	,	PUNCT
admet-505	781	16	g.e	g.e	PROPN
admet-505	781	17	.	.	PROPN
admet-505	781	18	amidon	amidon	PROPN
admet-505	781	19	.	.	PUNCT
admet-505	782	1	mechanistic	mechanistic	ADJ
admet-505	782	2	analysis	analysis	NOUN
admet-505	782	3	of	of	ADP
admet-505	782	4	cocrystal	cocrystal	ADJ
admet-505	782	5	dissolution	dissolution	NOUN
admet-505	782	6	as	as	ADP
admet-505	782	7	a	a	DET
admet-505	782	8	function	function	NOUN
admet-505	782	9	of	of	ADP
admet-505	782	10	ph	ph	ADJ
admet-505	782	11	and	and	CCONJ
admet-505	782	12	micellar	micellar	ADJ
admet-505	782	13	solubilization	solubilization	NOUN
admet-505	782	14	.	.	PUNCT
admet-505	783	1	mol	mol	PROPN
admet-505	783	2	.	.	PUNCT
admet-505	783	3	pharmaceutics	pharmaceutic	NOUN
admet-505	783	4	.	.	PUNCT
admet-505	784	1	13	13	NUM
admet-505	784	2	(	(	PUNCT
admet-505	784	3	2016	2016	NUM
admet-505	784	4	)	)	PUNCT
admet-505	784	5	1030	1030	NUM
admet-505	784	6	-	-	SYM
admet-505	784	7	1046	1046	NUM
admet-505	784	8	.	.	PUNCT
admet-505	785	1	[	[	X
admet-505	785	2	10	10	NUM
admet-505	785	3	]	]	X
admet-505	785	4	y.	y.	NOUN
admet-505	785	5	he	he	PRON
admet-505	785	6	,	,	PUNCT
admet-505	785	7	s.	s.	PROPN
admet-505	785	8	h.	h.	PROPN
admet-505	785	9	yalkowsky	yalkowsky	PROPN
admet-505	785	10	.	.	PUNCT
admet-505	786	1	solubilization	solubilization	NOUN
admet-505	786	2	of	of	ADP
admet-505	786	3	monovalent	monovalent	NOUN
admet-505	786	4	weak	weak	ADJ
admet-505	786	5	electrolytes	electrolyte	NOUN
admet-505	786	6	by	by	ADP
admet-505	786	7	micellization	micellization	NOUN
admet-505	786	8	or	or	CCONJ
admet-505	786	9	complexation	complexation	NOUN
admet-505	786	10	.	.	PUNCT
admet-505	787	1	int	int	NOUN
admet-505	787	2	.	.	PUNCT
admet-505	788	1	j.	j.	PROPN
admet-505	788	2	pharm	pharm	PROPN
admet-505	788	3	.	.	PUNCT
admet-505	789	1	314	314	NUM
admet-505	789	2	(	(	PUNCT
admet-505	789	3	2006	2006	NUM
admet-505	789	4	)	)	PUNCT
admet-505	789	5	15–20	15–20	NUM
admet-505	789	6	.	.	PUNCT
admet-505	790	1	[	[	X
admet-505	790	2	11	11	NUM
admet-505	790	3	]	]	X
admet-505	790	4	a.t	a.t	PROPN
admet-505	790	5	.	.	PROPN
admet-505	790	6	florence	florence	PROPN
admet-505	790	7	,	,	PUNCT
admet-505	790	8	d.	d.	PROPN
admet-505	790	9	attwood	attwood	PROPN
admet-505	790	10	.	.	PUNCT
admet-505	791	1	physicochemical	physicochemical	ADJ
admet-505	791	2	principles	principle	NOUN
admet-505	791	3	of	of	ADP
admet-505	791	4	pharmacy	pharmacy	NOUN
admet-505	791	5	–	–	PUNCT
admet-505	791	6	in	in	ADP
admet-505	791	7	manufacture	manufacture	NOUN
admet-505	791	8	,	,	PUNCT
admet-505	791	9	formulation	formulation	NOUN
admet-505	791	10	and	and	CCONJ
admet-505	791	11	clinical	clinical	ADJ
admet-505	791	12	use	use	NOUN
admet-505	791	13	.	.	PUNCT
admet-505	792	1	6th	6th	ADJ
admet-505	792	2	ed	ed	NOUN
admet-505	792	3	.	.	PROPN
admet-505	792	4	,	,	PUNCT
admet-505	792	5	pharmaceutical	pharmaceutical	NOUN
admet-505	792	6	press	press	NOUN
admet-505	792	7	,	,	PUNCT
admet-505	792	8	london	london	PROPN
admet-505	792	9	,	,	PUNCT
admet-505	792	10	2016	2016	NUM
admet-505	792	11	,	,	PUNCT
admet-505	792	12	pp	pp	ADJ
admet-505	792	13	.	.	PUNCT
admet-505	793	1	193	193	NUM
admet-505	793	2	-	-	SYM
admet-505	793	3	245	245	NUM
admet-505	793	4	.	.	PUNCT
admet-505	794	1	[	[	X
admet-505	794	2	12	12	NUM
admet-505	794	3	]	]	X
admet-505	794	4	e.	e.	PROPN
admet-505	794	5	pramauro	pramauro	PROPN
admet-505	794	6	,	,	PUNCT
admet-505	794	7	e.	e.	PROPN
admet-505	794	8	pelizzetti	pelizzetti	PROPN
admet-505	794	9	.	.	PUNCT
admet-505	795	1	surfactants	surfactant	NOUN
admet-505	795	2	in	in	ADP
admet-505	795	3	analytical	analytical	ADJ
admet-505	795	4	chemistry	chemistry	NOUN
admet-505	795	5	–	–	PUNCT
admet-505	795	6	applications	application	NOUN
admet-505	795	7	of	of	ADP
admet-505	795	8	organized	organized	ADJ
admet-505	795	9	amphiphilic	amphiphilic	ADJ
admet-505	795	10	media	medium	NOUN
admet-505	795	11	.	.	PUNCT
admet-505	796	1	elsevier	elsevier	NOUN
admet-505	796	2	,	,	PUNCT
admet-505	796	3	amsterdam	amsterdam	PROPN
admet-505	796	4	,	,	PUNCT
admet-505	796	5	1996	1996	NUM
admet-505	796	6	.	.	PUNCT
admet-505	797	1	[	[	X
admet-505	797	2	13	13	NUM
admet-505	797	3	]	]	PUNCT
admet-505	797	4	m.	m.	NOUN
admet-505	797	5	žegarac	žegarac	PROPN
admet-505	797	6	,	,	PUNCT
admet-505	797	7	e.	e.	PROPN
admet-505	797	8	lekšić	lekšić	PROPN
admet-505	797	9	,	,	PUNCT
admet-505	797	10	p.	p.	PROPN
admet-505	797	11	šket	šket	PROPN
admet-505	797	12	,	,	PUNCT
admet-505	797	13	j.	j.	PROPN
admet-505	797	14	plavec	plavec	PROPN
admet-505	797	15	,	,	PUNCT
admet-505	797	16	m.d	m.d	PROPN
admet-505	797	17	.	.	PROPN
admet-505	797	18	bogdanović	bogdanović	PROPN
admet-505	797	19	,	,	PUNCT
admet-505	797	20	d.-k	d.-k	PROPN
admet-505	797	21	.	.	PUNCT
admet-505	798	1	bučar	bučar	PROPN
admet-505	798	2	,	,	PUNCT
admet-505	798	3	m.	m.	NOUN
admet-505	798	4	dumić	dumić	PROPN
admet-505	798	5	,	,	PUNCT
admet-505	798	6	e.	e.	PROPN
admet-505	798	7	meštrović	meštrović	PROPN
admet-505	798	8	.	.	PUNCT
admet-505	799	1	a	a	DET
admet-505	799	2	sildenafil	sildenafil	NOUN
admet-505	799	3	cocrystal	cocrystal	NOUN
admet-505	799	4	based	base	VERB
admet-505	799	5	on	on	ADP
admet-505	799	6	acetylsalicylic	acetylsalicylic	PROPN
admet-505	799	7	acid	acid	PROPN
admet-505	799	8	exhibits	exhibit	VERB
admet-505	799	9	an	an	DET
admet-505	799	10	enhanced	enhanced	ADJ
admet-505	799	11	intrinsic	intrinsic	ADJ
admet-505	799	12	dissolution	dissolution	NOUN
admet-505	799	13	rate	rate	NOUN
admet-505	799	14	.	.	PUNCT
admet-505	800	1	cryst	cryst	PROPN
admet-505	800	2	.	.	PUNCT
admet-505	801	1	eng	eng	PROPN
admet-505	801	2	.	.	PROPN
admet-505	801	3	comm	comm	NOUN
admet-505	801	4	.	.	PUNCT
admet-505	802	1	16	16	NUM
admet-505	802	2	(	(	PUNCT
admet-505	802	3	2014	2014	NUM
admet-505	802	4	)	)	PUNCT
admet-505	802	5	32	32	NUM
admet-505	802	6	-	-	SYM
admet-505	802	7	35	35	NUM
admet-505	802	8	.	.	PUNCT
admet-505	803	1	[	[	X
admet-505	803	2	14	14	NUM
admet-505	803	3	]	]	X
admet-505	803	4	k.j	k.j	PROPN
admet-505	803	5	.	.	PROPN
admet-505	803	6	box	box	PROPN
admet-505	803	7	,	,	PUNCT
admet-505	803	8	j.	j.	PROPN
admet-505	803	9	comer	comer	PROPN
admet-505	803	10	,	,	PUNCT
admet-505	803	11	r.	r.	PROPN
admet-505	803	12	taylor	taylor	PROPN
admet-505	803	13	,	,	PUNCT
admet-505	803	14	s.	s.	PROPN
admet-505	803	15	karki	karki	PROPN
admet-505	803	16	,	,	PUNCT
admet-505	803	17	r.	r.	PROPN
admet-505	803	18	ruiz	ruiz	PROPN
admet-505	803	19	,	,	PUNCT
admet-505	803	20	r.	r.	PROPN
admet-505	803	21	price	price	NOUN
admet-505	803	22	,	,	PUNCT
admet-505	803	23	n.	n.	PROPN
admet-505	803	24	fotaki	fotaki	PROPN
admet-505	803	25	.	.	PUNCT
admet-505	804	1	small	small	ADJ
admet-505	804	2	-	-	PUNCT
admet-505	804	3	scale	scale	NOUN
admet-505	804	4	assays	assay	NOUN
admet-505	804	5	for	for	ADP
admet-505	804	6	studying	study	VERB
admet-505	804	7	dissolution	dissolution	NOUN
admet-505	804	8	of	of	ADP
admet-505	804	9	pharmaceutical	pharmaceutical	ADJ
admet-505	804	10	cocrystals	cocrystal	NOUN
admet-505	804	11	for	for	ADP
admet-505	804	12	oral	oral	ADJ
admet-505	804	13	administration	administration	NOUN
admet-505	804	14	.	.	PUNCT
admet-505	805	1	aaps	aap	NOUN
admet-505	805	2	pharmscitech	pharmscitech	VERB
admet-505	805	3	.	.	PUNCT
admet-505	806	1	17	17	NUM
admet-505	806	2	(	(	PUNCT
admet-505	806	3	2016	2016	NUM
admet-505	806	4	)	)	PUNCT
admet-505	806	5	245	245	NUM
admet-505	806	6	-	-	SYM
admet-505	806	7	251	251	NUM
admet-505	806	8	.	.	PUNCT
admet-505	807	1	[	[	X
admet-505	807	2	15	15	NUM
admet-505	807	3	]	]	X
admet-505	807	4	d.p	d.p	PROPN
admet-505	807	5	.	.	PUNCT
admet-505	808	1	mcnamara	mcnamara	PROPN
admet-505	808	2	,	,	PUNCT
admet-505	808	3	s.l	s.l	PROPN
admet-505	808	4	.	.	PROPN
admet-505	808	5	childs	childs	PROPN
admet-505	808	6	,	,	PUNCT
admet-505	808	7	j.	j.	PROPN
admet-505	808	8	giordano	giordano	PROPN
admet-505	808	9	,	,	PUNCT
admet-505	808	10	a.	a.	NOUN
admet-505	808	11	iarriccio	iarriccio	PROPN
admet-505	808	12	,	,	PUNCT
admet-505	808	13	j.	j.	PROPN
admet-505	808	14	cassidy	cassidy	PROPN
admet-505	808	15	,	,	PUNCT
admet-505	808	16	m.s	m.s	PROPN
admet-505	808	17	.	.	PROPN
admet-505	808	18	shet	shet	PROPN
admet-505	808	19	,	,	PUNCT
admet-505	808	20	r.	r.	PROPN
admet-505	808	21	mannion	mannion	PROPN
admet-505	808	22	,	,	PUNCT
admet-505	808	23	e.	e.	PROPN
admet-505	808	24	o’donnell	o’donnell	PROPN
admet-505	808	25	,	,	PUNCT
admet-505	808	26	a.	a.	NOUN
admet-505	808	27	park	park	NOUN
admet-505	808	28	.	.	PUNCT
admet-505	809	1	use	use	NOUN
admet-505	809	2	of	of	ADP
admet-505	809	3	a	a	DET
admet-505	809	4	glutaric	glutaric	ADJ
admet-505	809	5	acid	acid	NOUN
admet-505	809	6	cocrystal	cocrystal	NOUN
admet-505	809	7	to	to	PART
admet-505	809	8	improve	improve	VERB
admet-505	809	9	oral	oral	ADJ
admet-505	809	10	bioavailability	bioavailability	NOUN
admet-505	809	11	of	of	ADP
admet-505	809	12	a	a	DET
admet-505	809	13	low	low	ADJ
admet-505	809	14	solubility	solubility	NOUN
admet-505	809	15	api	api	NOUN
admet-505	809	16	.	.	PUNCT
admet-505	810	1	pharm	pharm	PROPN
admet-505	810	2	.	.	PUNCT
admet-505	811	1	res	re	NOUN
admet-505	811	2	.	.	PUNCT
admet-505	812	1	23	23	NUM
admet-505	812	2	(	(	PUNCT
admet-505	812	3	2006	2006	NUM
admet-505	812	4	)	)	PUNCT
admet-505	812	5	1888	1888	NUM
admet-505	812	6	-	-	SYM
admet-505	812	7	1897	1897	NUM
admet-505	812	8	.	.	PUNCT
admet-505	813	1	[	[	X
admet-505	813	2	16	16	NUM
admet-505	813	3	]	]	PUNCT
admet-505	813	4	a.	a.	NOUN
admet-505	813	5	avdeef	avdeef	PROPN
admet-505	813	6	.	.	PUNCT
admet-505	814	1	cocrystal	cocrystal	PROPN
admet-505	814	2	solubility	solubility	NOUN
admet-505	814	3	product	product	NOUN
admet-505	814	4	analysis	analysis	NOUN
admet-505	814	5	–	–	PUNCT
admet-505	814	6	dual	dual	ADJ
admet-505	814	7	concentration	concentration	NOUN
admet-505	814	8	-	-	PUNCT
admet-505	814	9	ph	ph	ADJ
admet-505	814	10	mass	mass	NOUN
admet-505	814	11	action	action	NOUN
admet-505	814	12	model	model	NOUN
admet-505	814	13	not	not	PART
admet-505	814	14	dependent	dependent	ADJ
admet-505	814	15	on	on	ADP
admet-505	814	16	explicit	explicit	ADJ
admet-505	814	17	solubility	solubility	NOUN
admet-505	814	18	equations	equation	NOUN
admet-505	814	19	.	.	PUNCT
admet-505	815	1	eur	eur	PROPN
admet-505	815	2	.	.	PUNCT
admet-505	816	1	j.	j.	PROPN
admet-505	816	2	pharm	pharm	PROPN
admet-505	816	3	.	.	PUNCT
admet-505	817	1	sci	sci	PROPN
admet-505	817	2	.	.	PROPN
admet-505	818	1	110	110	NUM
admet-505	818	2	(	(	PUNCT
admet-505	818	3	2017	2017	NUM
admet-505	818	4	)	)	PUNCT
admet-505	818	5	2	2	NUM
admet-505	818	6	-	-	SYM
admet-505	818	7	18	18	NUM
admet-505	818	8	.	.	PUNCT
admet-505	819	1	[	[	X
admet-505	819	2	17	17	NUM
admet-505	819	3	]	]	PUNCT
admet-505	819	4	a.	a.	NOUN
admet-505	819	5	avdeef	avdeef	PROPN
admet-505	819	6	.	.	PUNCT
admet-505	820	1	cocrystal	cocrystal	PROPN
admet-505	820	2	solubility	solubility	NOUN
admet-505	820	3	product	product	NOUN
admet-505	820	4	prediction	prediction	NOUN
admet-505	820	5	using	use	VERB
admet-505	820	6	an	an	DET
admet-505	820	7	in	in	ADP
admet-505	820	8	combo	combo	NOUN
admet-505	820	9	model	model	NOUN
admet-505	820	10	and	and	CCONJ
admet-505	820	11	simulations	simulation	NOUN
admet-505	820	12	to	to	PART
admet-505	820	13	improve	improve	VERB
admet-505	820	14	design	design	NOUN
admet-505	820	15	of	of	ADP
admet-505	820	16	experiments	experiment	NOUN
admet-505	820	17	.	.	PUNCT
admet-505	821	1	pharm	pharm	NOUN
admet-505	821	2	.	.	PUNCT
admet-505	822	1	res	re	NOUN
admet-505	822	2	.	.	PUNCT
admet-505	823	1	(	(	PUNCT
admet-505	823	2	2018	2018	NUM
admet-505	823	3	)	)	PUNCT
admet-505	823	4	35	35	NUM
admet-505	823	5	:	:	SYM
admet-505	823	6	40	40	NUM
admet-505	823	7	.	.	PUNCT
admet-505	824	1	https://doi.org/10.1007/s11095-018-2343-3	https://doi.org/10.1007/s11095-018-2343-3	PROPN
admet-505	824	2	.	.	PUNCT
admet-505	825	1	admet	admet	PROPN
admet-505	825	2	&	&	CCONJ
admet-505	825	3	dmpk	dmpk	PROPN
admet-505	825	4	6(2	6(2	NUM
admet-505	825	5	)	)	PUNCT
admet-505	825	6	(	(	PUNCT
admet-505	825	7	2018	2018	NUM
admet-505	825	8	)	)	PUNCT
admet-505	825	9	105	105	NUM
admet-505	825	10	-	-	SYM
admet-505	825	11	139	139	NUM
admet-505	825	12	cocrystal	cocrystal	ADJ
admet-505	825	13	solubility	solubility	NOUN
admet-505	825	14	-	-	PUNCT
admet-505	825	15	ph	ph	VERB
admet-505	825	16	,	,	PUNCT
admet-505	825	17	drug	drug	NOUN
admet-505	825	18	solubilization	solubilization	NOUN
admet-505	825	19	capacity	capacity	NOUN
admet-505	825	20	of	of	ADP
admet-505	825	21	sds	sds	PROPN
admet-505	825	22	,	,	PUNCT
admet-505	825	23	mass	mass	ADJ
admet-505	825	24	action	action	NOUN
admet-505	825	25	model	model	NOUN
admet-505	825	26	doi	doi	PROPN
admet-505	825	27	:	:	PUNCT
admet-505	825	28	10.5599	10.5599	NUM
admet-505	825	29	/	/	SYM
admet-505	825	30	admet.505	admet.505	PROPN
admet-505	825	31	135	135	NUM
admet-505	825	32	[	[	SYM
admet-505	825	33	18	18	NUM
admet-505	825	34	]	]	X
admet-505	825	35	e.	e.	PROPN
admet-505	825	36	fuguet	fuguet	PROPN
admet-505	825	37	,	,	PUNCT
admet-505	825	38	c.	c.	NOUN
admet-505	825	39	ràfols	ràfol	NOUN
admet-505	825	40	,	,	PUNCT
admet-505	825	41	m.	m.	NOUN
admet-505	825	42	rosés	rosés	PROPN
admet-505	825	43	,	,	PUNCT
admet-505	825	44	e.	e.	PROPN
admet-505	825	45	bosch	bosch	PROPN
admet-505	825	46	.	.	PUNCT
admet-505	826	1	critical	critical	ADJ
admet-505	826	2	micelle	micelle	NOUN
admet-505	826	3	concentration	concentration	NOUN
admet-505	826	4	of	of	ADP
admet-505	826	5	surfactants	surfactant	NOUN
admet-505	826	6	in	in	ADP
admet-505	826	7	aqueous	aqueous	ADJ
admet-505	826	8	buffered	buffer	VERB
admet-505	826	9	and	and	CCONJ
admet-505	826	10	unbuffered	unbuffered	ADJ
admet-505	826	11	systems	system	NOUN
admet-505	826	12	.	.	PUNCT
admet-505	827	1	anal	anal	PROPN
admet-505	827	2	.	.	PUNCT
admet-505	828	1	chim	chim	PROPN
admet-505	828	2	.	.	PUNCT
admet-505	829	1	acta	acta	PROPN
admet-505	829	2	548	548	NUM
admet-505	829	3	(	(	PUNCT
admet-505	829	4	2005	2005	NUM
admet-505	829	5	)	)	PUNCT
admet-505	829	6	95–100	95–100	NUM
admet-505	829	7	.	.	PUNCT
admet-505	830	1	[	[	X
admet-505	830	2	19	19	NUM
admet-505	830	3	]	]	PUNCT
admet-505	830	4	a.m.	a.m.	PROPN
admet-505	830	5	khan	khan	PROPN
admet-505	830	6	,	,	PUNCT
admet-505	830	7	s.s	s.s	PROPN
admet-505	830	8	.	.	PROPN
admet-505	830	9	shah	shah	PROPN
admet-505	830	10	.	.	PUNCT
admet-505	831	1	determination	determination	NOUN
admet-505	831	2	of	of	ADP
admet-505	831	3	critical	critical	ADJ
admet-505	831	4	micelle	micelle	NOUN
admet-505	831	5	concentration	concentration	NOUN
admet-505	831	6	(	(	PUNCT
admet-505	831	7	cmc	cmc	NOUN
admet-505	831	8	)	)	PUNCT
admet-505	831	9	of	of	ADP
admet-505	831	10	sodium	sodium	NOUN
admet-505	831	11	dodecyl	dodecyl	PROPN
admet-505	831	12	sulfate	sulfate	PROPN
admet-505	831	13	(	(	PUNCT
admet-505	831	14	sds	sds	PROPN
admet-505	831	15	)	)	PUNCT
admet-505	831	16	and	and	CCONJ
admet-505	831	17	the	the	DET
admet-505	831	18	effect	effect	NOUN
admet-505	831	19	of	of	ADP
admet-505	831	20	low	low	ADJ
admet-505	831	21	concentration	concentration	NOUN
admet-505	831	22	of	of	ADP
admet-505	831	23	pyrene	pyrene	NOUN
admet-505	831	24	on	on	ADP
admet-505	831	25	its	its	PRON
admet-505	831	26	cmc	cmc	NOUN
admet-505	831	27	using	use	VERB
admet-505	831	28	origin	origin	NOUN
admet-505	831	29	software	software	NOUN
admet-505	831	30	.	.	PUNCT
admet-505	832	1	j.chem.soc	j.chem.soc	PROPN
admet-505	832	2	.	.	PROPN
admet-505	832	3	pak	pak	PROPN
admet-505	832	4	.	.	PROPN
admet-505	833	1	30	30	NUM
admet-505	833	2	(	(	PUNCT
admet-505	833	3	2008	2008	NUM
admet-505	833	4	)	)	PUNCT
admet-505	833	5	186	186	NUM
admet-505	833	6	-	-	SYM
admet-505	833	7	191	191	NUM
admet-505	833	8	.	.	PUNCT
admet-505	834	1	[	[	X
admet-505	834	2	20	20	NUM
admet-505	834	3	]	]	X
admet-505	834	4	a.s	a.s	PROPN
admet-505	834	5	.	.	PROPN
admet-505	834	6	indulkar	indulkar	PROPN
admet-505	834	7	,	,	PUNCT
admet-505	834	8	h.	h.	PROPN
admet-505	834	9	mo	mo	PROPN
admet-505	834	10	,	,	PUNCT
admet-505	834	11	y.	y.	PROPN
admet-505	834	12	gao	gao	PROPN
admet-505	834	13	,	,	PUNCT
admet-505	834	14	s.a	s.a	PROPN
admet-505	834	15	.	.	PROPN
admet-505	834	16	raina	raina	PROPN
admet-505	834	17	,	,	PUNCT
admet-505	834	18	g.g.z	g.g.z	PROPN
admet-505	834	19	.	.	PUNCT
admet-505	835	1	zhang	zhang	PROPN
admet-505	835	2	,	,	PUNCT
admet-505	835	3	l.s	l.s	PROPN
admet-505	835	4	.	.	PROPN
admet-505	835	5	taylor	taylor	PROPN
admet-505	835	6	.	.	PUNCT
admet-505	835	7	impact	impact	NOUN
admet-505	835	8	of	of	ADP
admet-505	835	9	micellar	micellar	ADJ
admet-505	835	10	surfactant	surfactant	NOUN
admet-505	835	11	on	on	ADP
admet-505	835	12	supersaturation	supersaturation	NOUN
admet-505	835	13	and	and	CCONJ
admet-505	835	14	insight	insight	NOUN
admet-505	835	15	into	into	ADP
admet-505	835	16	solubilization	solubilization	NOUN
admet-505	835	17	mechanisms	mechanism	NOUN
admet-505	835	18	in	in	ADP
admet-505	835	19	supersaturated	supersaturated	ADJ
admet-505	835	20	solutions	solution	NOUN
admet-505	835	21	of	of	ADP
admet-505	835	22	atazanavir	atazanavir	PROPN
admet-505	835	23	.	.	PUNCT
admet-505	836	1	pharm	pharm	PROPN
admet-505	836	2	.	.	PUNCT
admet-505	837	1	res	re	NOUN
admet-505	837	2	.	.	PUNCT
admet-505	838	1	34	34	NUM
admet-505	838	2	(	(	PUNCT
admet-505	838	3	2017	2017	NUM
admet-505	838	4	)	)	PUNCT
admet-505	838	5	1276–1295	1276–1295	NUM
admet-505	838	6	.	.	PUNCT
admet-505	839	1	[	[	X
admet-505	839	2	21	21	NUM
admet-505	839	3	]	]	X
admet-505	839	4	g.	g.	PROPN
admet-505	839	5	völgyi	völgyi	PROPN
admet-505	839	6	,	,	PUNCT
admet-505	839	7	a.	a.	NOUN
admet-505	839	8	marosi	marosi	PROPN
admet-505	839	9	,	,	PUNCT
admet-505	839	10	k.	k.	PROPN
admet-505	839	11	takács	takács	PROPN
admet-505	839	12	-	-	PUNCT
admet-505	839	13	novák	novák	PROPN
admet-505	839	14	,	,	PUNCT
admet-505	839	15	a.	a.	NOUN
admet-505	839	16	avdeef	avdeef	PROPN
admet-505	839	17	.	.	PUNCT
admet-505	840	1	salt	salt	NOUN
admet-505	840	2	solubility	solubility	NOUN
admet-505	840	3	products	product	NOUN
admet-505	840	4	of	of	ADP
admet-505	840	5	diprenorphine	diprenorphine	NOUN
admet-505	840	6	hydrochloride	hydrochloride	NOUN
admet-505	840	7	,	,	PUNCT
admet-505	840	8	codeine	codeine	NOUN
admet-505	840	9	and	and	CCONJ
admet-505	840	10	lidocaine	lidocaine	NOUN
admet-505	840	11	hydrochlorides	hydrochloride	NOUN
admet-505	840	12	and	and	CCONJ
admet-505	840	13	phosphates	phosphate	NOUN
admet-505	840	14	–	–	PUNCT
admet-505	840	15	novel	novel	NOUN
admet-505	840	16	method	method	NOUN
admet-505	840	17	of	of	ADP
admet-505	840	18	data	datum	NOUN
admet-505	840	19	analysis	analysis	NOUN
admet-505	840	20	not	not	PART
admet-505	840	21	dependent	dependent	ADJ
admet-505	840	22	on	on	ADP
admet-505	840	23	explicit	explicit	ADJ
admet-505	840	24	solubility	solubility	NOUN
admet-505	840	25	equations	equation	NOUN
admet-505	840	26	.	.	PUNCT
admet-505	841	1	admet	admet	PROPN
admet-505	841	2	&	&	CCONJ
admet-505	841	3	dmpk	dmpk	PROPN
admet-505	841	4	1	1	NUM
admet-505	841	5	(	(	PUNCT
admet-505	841	6	2013	2013	NUM
admet-505	841	7	)	)	PUNCT
admet-505	841	8	48	48	NUM
admet-505	841	9	-	-	SYM
admet-505	841	10	62	62	NUM
admet-505	841	11	.	.	PUNCT
admet-505	842	1	[	[	X
admet-505	842	2	22	22	NUM
admet-505	842	3	]	]	PUNCT
admet-505	842	4	a.	a.	NOUN
admet-505	842	5	avdeef	avdeef	PROPN
admet-505	842	6	.	.	PUNCT
admet-505	843	1	anomalous	anomalous	ADJ
admet-505	843	2	solubility	solubility	NOUN
admet-505	843	3	behavior	behavior	NOUN
admet-505	843	4	of	of	ADP
admet-505	843	5	several	several	ADJ
admet-505	843	6	acidic	acidic	ADJ
admet-505	843	7	drugs	drug	NOUN
admet-505	843	8	.	.	PUNCT
admet-505	844	1	admet	admet	PROPN
admet-505	844	2	&	&	CCONJ
admet-505	844	3	dmpk	dmpk	PROPN
admet-505	844	4	2	2	NUM
admet-505	844	5	(	(	PUNCT
admet-505	844	6	2014	2014	NUM
admet-505	844	7	)	)	PUNCT
admet-505	844	8	33	33	NUM
admet-505	844	9	-	-	SYM
admet-505	844	10	42	42	NUM
admet-505	844	11	.	.	PUNCT
admet-505	845	1	[	[	X
admet-505	845	2	23	23	NUM
admet-505	845	3	]	]	PUNCT
admet-505	845	4	a.	a.	NOUN
admet-505	845	5	avdeef	avdeef	PROPN
admet-505	845	6	.	.	PUNCT
admet-505	846	1	phosphate	phosphate	ADJ
admet-505	846	2	precipitates	precipitate	NOUN
admet-505	846	3	and	and	CCONJ
admet-505	846	4	water	water	NOUN
admet-505	846	5	-	-	PUNCT
admet-505	846	6	soluble	soluble	ADJ
admet-505	846	7	aggregates	aggregate	NOUN
admet-505	846	8	in	in	ADP
admet-505	846	9	re	re	VERB
admet-505	846	10	-	-	VERB
admet-505	846	11	examined	examine	VERB
admet-505	846	12	solubility	solubility	NOUN
admet-505	846	13	-	-	PUNCT
admet-505	846	14	ph	ph	ADJ
admet-505	846	15	data	datum	NOUN
admet-505	846	16	of	of	ADP
admet-505	846	17	twenty	twenty	NUM
admet-505	846	18	-	-	PUNCT
admet-505	846	19	five	five	NUM
admet-505	846	20	basic	basic	ADJ
admet-505	846	21	drugs	drug	NOUN
admet-505	846	22	.	.	PUNCT
admet-505	847	1	admet	admet	PROPN
admet-505	847	2	&	&	CCONJ
admet-505	847	3	dmpk	dmpk	PROPN
admet-505	847	4	2	2	NUM
admet-505	847	5	(	(	PUNCT
admet-505	847	6	2014	2014	NUM
admet-505	847	7	)	)	PUNCT
admet-505	847	8	43	43	NUM
admet-505	847	9	-	-	SYM
admet-505	847	10	55	55	NUM
admet-505	847	11	.	.	PUNCT
admet-505	848	1	[	[	X
admet-505	848	2	24	24	NUM
admet-505	848	3	]	]	PUNCT
admet-505	848	4	g.	g.	NOUN
admet-505	848	5	butcher	butcher	PROPN
admet-505	848	6	,	,	PUNCT
admet-505	848	7	j.	j.	PROPN
admet-505	848	8	comer	comer	PROPN
admet-505	848	9	,	,	PUNCT
admet-505	848	10	a.	a.	NOUN
admet-505	848	11	avdeef	avdeef	PROPN
admet-505	848	12	.	.	PUNCT
admet-505	849	1	pka	pka	ADJ
admet-505	849	2	-	-	ADJ
admet-505	849	3	critical	critical	ADJ
admet-505	849	4	interpretations	interpretation	NOUN
admet-505	849	5	of	of	ADP
admet-505	849	6	solubility	solubility	NOUN
admet-505	849	7	-	-	PUNCT
admet-505	849	8	ph	ph	ADJ
admet-505	849	9	profiles	profile	NOUN
admet-505	849	10	:	:	PUNCT
admet-505	849	11	pg-300995	pg-300995	NOUN
admet-505	849	12	and	and	CCONJ
admet-505	849	13	nsc-639829	nsc-639829	NOUN
admet-505	849	14	case	case	NOUN
admet-505	849	15	studies	study	NOUN
admet-505	849	16	.	.	PUNCT
admet-505	850	1	admet	admet	PROPN
admet-505	850	2	&	&	CCONJ
admet-505	850	3	dmpk	dmpk	PROPN
admet-505	850	4	3	3	NUM
admet-505	850	5	(	(	PUNCT
admet-505	850	6	2015	2015	NUM
admet-505	850	7	)	)	PUNCT
admet-505	850	8	131	131	NUM
admet-505	850	9	-	-	SYM
admet-505	850	10	140	140	NUM
admet-505	850	11	.	.	PUNCT
admet-505	851	1	[	[	X
admet-505	851	2	25	25	NUM
admet-505	851	3	]	]	PUNCT
admet-505	851	4	a.	a.	NOUN
admet-505	851	5	pobudkowska	pobudkowska	PROPN
admet-505	851	6	,	,	PUNCT
admet-505	851	7	c.	c.	PROPN
admet-505	851	8	ràfols	ràfol	NOUN
admet-505	851	9	,	,	PUNCT
admet-505	851	10	x.	x.	NOUN
admet-505	851	11	subirats	subirats	PROPN
admet-505	851	12	,	,	PUNCT
admet-505	851	13	e.	e.	PROPN
admet-505	851	14	bosch	bosch	PROPN
admet-505	851	15	,	,	PUNCT
admet-505	851	16	a.	a.	PROPN
admet-505	851	17	avdeef	avdeef	PROPN
admet-505	851	18	.	.	PUNCT
admet-505	852	1	phenothiazines	phenothiazine	NOUN
admet-505	852	2	solution	solution	NOUN
admet-505	852	3	complexity	complexity	NOUN
admet-505	852	4	–	–	PUNCT
admet-505	852	5	determination	determination	NOUN
admet-505	852	6	of	of	ADP
admet-505	852	7	pka	pka	PROPN
admet-505	852	8	and	and	CCONJ
admet-505	852	9	solubility	solubility	NOUN
admet-505	852	10	-	-	PUNCT
admet-505	852	11	ph	ph	ADJ
admet-505	852	12	profiles	profile	NOUN
admet-505	852	13	exhibiting	exhibit	VERB
admet-505	852	14	sub	sub	ADJ
admet-505	852	15	-	-	ADJ
admet-505	852	16	micellar	micellar	ADJ
admet-505	852	17	aggregation	aggregation	NOUN
admet-505	852	18	at	at	ADP
admet-505	852	19	25	25	NUM
admet-505	852	20	and	and	CCONJ
admet-505	852	21	37	37	NUM
admet-505	852	22	o	o	PROPN
admet-505	852	23	c.	c.	PROPN
admet-505	852	24	eur	eur	PROPN
admet-505	852	25	.	.	PUNCT
admet-505	853	1	j.	j.	PROPN
admet-505	853	2	pharm	pharm	PROPN
admet-505	853	3	.	.	PUNCT
admet-505	854	1	sci	sci	PROPN
admet-505	854	2	.	.	PROPN
admet-505	855	1	93	93	NUM
admet-505	855	2	(	(	PUNCT
admet-505	855	3	2016	2016	NUM
admet-505	855	4	)	)	PUNCT
admet-505	855	5	163	163	NUM
admet-505	855	6	-	-	SYM
admet-505	855	7	176	176	NUM
admet-505	855	8	.	.	PUNCT
admet-505	856	1	[	[	X
admet-505	856	2	26	26	NUM
admet-505	856	3	]	]	PUNCT
admet-505	856	4	a.	a.	NOUN
admet-505	856	5	avdeef	avdeef	PROPN
admet-505	856	6	.	.	PUNCT
admet-505	857	1	solubility	solubility	NOUN
admet-505	857	2	temperature	temperature	NOUN
admet-505	857	3	dependence	dependence	NOUN
admet-505	857	4	predicted	predict	VERB
admet-505	857	5	from	from	ADP
admet-505	857	6	2d	2d	NUM
admet-505	857	7	structure	structure	NOUN
admet-505	857	8	.	.	PUNCT
admet-505	858	1	admet	admet	PROPN
admet-505	858	2	&	&	CCONJ
admet-505	858	3	dmpk	dmpk	PROPN
admet-505	858	4	3	3	NUM
admet-505	858	5	(	(	PUNCT
admet-505	858	6	2015	2015	NUM
admet-505	858	7	)	)	PUNCT
admet-505	858	8	298	298	NUM
admet-505	858	9	-	-	SYM
admet-505	858	10	344	344	NUM
admet-505	858	11	.	.	PUNCT
admet-505	859	1	[	[	X
admet-505	859	2	27	27	NUM
admet-505	859	3	]	]	PUNCT
admet-505	859	4	a.	a.	NOUN
admet-505	859	5	avdeef	avdeef	PROPN
admet-505	859	6	.	.	PUNCT
admet-505	860	1	absorption	absorption	NOUN
admet-505	860	2	and	and	CCONJ
admet-505	860	3	drug	drug	NOUN
admet-505	860	4	development	development	NOUN
admet-505	860	5	,	,	PUNCT
admet-505	860	6	second	second	ADJ
admet-505	860	7	edition	edition	NOUN
admet-505	860	8	.	.	PUNCT
admet-505	861	1	wiley	wiley	PROPN
admet-505	861	2	-	-	PUNCT
admet-505	861	3	interscience	interscience	PROPN
admet-505	861	4	,	,	PUNCT
admet-505	861	5	hoboken	hoboken	PROPN
admet-505	861	6	,	,	PUNCT
admet-505	861	7	nj	nj	PROPN
admet-505	861	8	,	,	PUNCT
admet-505	861	9	2012	2012	NUM
admet-505	861	10	.	.	PUNCT
admet-505	862	1	[	[	X
admet-505	862	2	28	28	NUM
admet-505	862	3	]	]	X
admet-505	862	4	s.	s.	PROPN
admet-505	862	5	lapenna	lapenna	PROPN
admet-505	862	6	s	s	PROPN
admet-505	862	7	,	,	PUNCT
admet-505	862	8	a.r	a.r	PROPN
admet-505	862	9	.	.	PROPN
admet-505	862	10	bilia	bilia	PROPN
admet-505	862	11	,	,	PUNCT
admet-505	862	12	g.a	g.a	PROPN
admet-505	862	13	.	.	PROPN
admet-505	862	14	morris	morris	PROPN
admet-505	862	15	,	,	PUNCT
admet-505	862	16	m.	m.	NOUN
admet-505	862	17	nilsson	nilsson	PROPN
admet-505	862	18	m.	m.	PROPN
admet-505	862	19	novel	novel	PROPN
admet-505	862	20	artemisinin	artemisinin	PROPN
admet-505	862	21	and	and	CCONJ
admet-505	862	22	curcumin	curcumin	NOUN
admet-505	862	23	micellar	micellar	NOUN
admet-505	862	24	formulations	formulation	NOUN
admet-505	862	25	:	:	PUNCT
admet-505	862	26	drug	drug	NOUN
admet-505	862	27	solubility	solubility	NOUN
admet-505	862	28	studies	study	NOUN
admet-505	862	29	by	by	ADP
admet-505	862	30	nmr	nmr	NOUN
admet-505	862	31	spectroscopy	spectroscopy	NOUN
admet-505	862	32	.	.	PUNCT
admet-505	863	1	j.	j.	PROPN
admet-505	863	2	pharm	pharm	PROPN
admet-505	863	3	.	.	PUNCT
admet-505	864	1	sci	sci	PROPN
admet-505	864	2	.	.	PROPN
admet-505	865	1	98	98	NUM
admet-505	865	2	(	(	PUNCT
admet-505	865	3	2009	2009	NUM
admet-505	865	4	)	)	PUNCT
admet-505	865	5	3666	3666	NUM
admet-505	865	6	-	-	PUNCT
admet-505	865	7	367515	367515	NUM
admet-505	865	8	.	.	PUNCT
admet-505	866	1	[	[	X
admet-505	866	2	29	29	NUM
admet-505	866	3	]	]	X
admet-505	866	4	a.s	a.s	PROPN
admet-505	866	5	.	.	PROPN
admet-505	866	6	indulkar	indulkar	PROPN
admet-505	866	7	,	,	PUNCT
admet-505	866	8	h.	h.	PROPN
admet-505	866	9	mo	mo	PROPN
admet-505	866	10	,	,	PUNCT
admet-505	866	11	y.	y.	PROPN
admet-505	866	12	gao	gao	PROPN
admet-505	866	13	,	,	PUNCT
admet-505	866	14	s.a	s.a	PROPN
admet-505	866	15	.	.	PROPN
admet-505	866	16	raina	raina	PROPN
admet-505	866	17	,	,	PUNCT
admet-505	866	18	g.g.z	g.g.z	PROPN
admet-505	866	19	.	.	PUNCT
admet-505	867	1	zhang	zhang	PROPN
admet-505	867	2	,	,	PUNCT
admet-505	867	3	l.s	l.s	PROPN
admet-505	867	4	.	.	PROPN
admet-505	867	5	taylor	taylor	PROPN
admet-505	867	6	.	.	PUNCT
admet-505	867	7	impact	impact	NOUN
admet-505	867	8	of	of	ADP
admet-505	867	9	micellar	micellar	ADJ
admet-505	867	10	surfactant	surfactant	NOUN
admet-505	867	11	on	on	ADP
admet-505	867	12	supersaturation	supersaturation	NOUN
admet-505	867	13	and	and	CCONJ
admet-505	867	14	insight	insight	NOUN
admet-505	867	15	into	into	ADP
admet-505	867	16	solubilization	solubilization	NOUN
admet-505	867	17	mechanisms	mechanism	NOUN
admet-505	867	18	in	in	ADP
admet-505	867	19	supersaturated	supersaturated	ADJ
admet-505	867	20	solutions	solution	NOUN
admet-505	867	21	of	of	ADP
admet-505	867	22	atazanavir	atazanavir	PROPN
admet-505	867	23	.	.	PUNCT
admet-505	868	1	pharm	pharm	PROPN
admet-505	868	2	.	.	PUNCT
admet-505	869	1	res	re	NOUN
admet-505	869	2	.	.	PUNCT
admet-505	870	1	34	34	NUM
admet-505	870	2	(	(	PUNCT
admet-505	870	3	2017	2017	NUM
admet-505	870	4	)	)	PUNCT
admet-505	870	5	1276–1295	1276–1295	NUM
admet-505	870	6	.	.	PUNCT
admet-505	871	1	[	[	X
admet-505	871	2	30	30	NUM
admet-505	871	3	]	]	X
admet-505	871	4	k.m.s	k.m.s	X
admet-505	871	5	.	.	PROPN
admet-505	871	6	fahelelbom	fahelelbom	PROPN
admet-505	871	7	,	,	PUNCT
admet-505	871	8	r.f	r.f	PROPN
admet-505	871	9	.	.	PROPN
admet-505	871	10	timoney	timoney	PROPN
admet-505	871	11	,	,	PUNCT
admet-505	871	12	o.i	o.i	PROPN
admet-505	871	13	.	.	PROPN
admet-505	871	14	corrigan	corrigan	PROPN
admet-505	871	15	.	.	PUNCT
admet-505	872	1	micellar	micellar	ADJ
admet-505	872	2	solubilization	solubilization	NOUN
admet-505	872	3	of	of	ADP
admet-505	872	4	clofazimine	clofazimine	ADJ
admet-505	872	5	analogues	analogue	NOUN
admet-505	872	6	in	in	ADP
admet-505	872	7	aqueous	aqueous	ADJ
admet-505	872	8	solutions	solution	NOUN
admet-505	872	9	of	of	ADP
admet-505	872	10	ionic	ionic	ADJ
admet-505	872	11	and	and	CCONJ
admet-505	872	12	nonionic	nonionic	ADJ
admet-505	872	13	surfactants	surfactant	NOUN
admet-505	872	14	.	.	PUNCT
admet-505	873	1	pharm	pharm	NOUN
admet-505	873	2	.	.	PUNCT
admet-505	874	1	res	re	NOUN
admet-505	874	2	.	.	PROPN
admet-505	875	1	10	10	NUM
admet-505	875	2	(	(	PUNCT
admet-505	875	3	1993	1993	NUM
admet-505	875	4	)	)	PUNCT
admet-505	875	5	631	631	NUM
admet-505	875	6	-	-	SYM
admet-505	875	7	634	634	NUM
admet-505	875	8	.	.	PUNCT
admet-505	876	1	[	[	X
admet-505	876	2	31	31	NUM
admet-505	876	3	]	]	PUNCT
admet-505	876	4	a.	a.	NOUN
admet-505	876	5	garrone	garrone	NOUN
admet-505	876	6	,	,	PUNCT
admet-505	876	7	e.	e.	PROPN
admet-505	876	8	marengo	marengo	PROPN
admet-505	876	9	,	,	PUNCT
admet-505	876	10	e.	e.	PROPN
admet-505	876	11	fornatto	fornatto	PROPN
admet-505	876	12	,	,	PUNCT
admet-505	876	13	a.	a.	NOUN
admet-505	876	14	gasco	gasco	NOUN
admet-505	876	15	.	.	PUNCT
admet-505	877	1	a	a	DET
admet-505	877	2	study	study	NOUN
admet-505	877	3	on	on	ADP
admet-505	877	4	pka	pka	PROPN
admet-505	877	5	app	app	PROPN
admet-505	877	6	and	and	CCONJ
admet-505	877	7	partition	partition	NOUN
admet-505	877	8	coefficient	coefficient	NOUN
admet-505	877	9	of	of	ADP
admet-505	877	10	substituted	substitute	VERB
admet-505	877	11	benzoic	benzoic	NOUN
admet-505	877	12	acids	acid	NOUN
admet-505	877	13	in	in	ADP
admet-505	877	14	sds	sds	PROPN
admet-505	877	15	anionic	anionic	ADJ
admet-505	877	16	micellar	micellar	NOUN
admet-505	877	17	system	system	NOUN
admet-505	877	18	.	.	PUNCT
admet-505	878	1	quant	quant	NOUN
admet-505	878	2	.	.	PUNCT
admet-505	878	3	struct.-act	struct.-act	PROPN
admet-505	878	4	.	.	PUNCT
admet-505	879	1	relat	relat	PROPN
admet-505	879	2	.	.	PUNCT
admet-505	880	1	11	11	NUM
admet-505	880	2	(	(	PUNCT
admet-505	880	3	1992	1992	NUM
admet-505	880	4	)	)	PUNCT
admet-505	880	5	171	171	NUM
admet-505	880	6	-	-	SYM
admet-505	880	7	175	175	NUM
admet-505	880	8	.	.	PUNCT
admet-505	881	1	[	[	X
admet-505	881	2	32	32	NUM
admet-505	881	3	]	]	X
admet-505	881	4	j.r	j.r	PROPN
admet-505	881	5	.	.	PROPN
admet-505	881	6	crison	crison	PROPN
admet-505	881	7	,	,	PUNCT
admet-505	881	8	v.p	v.p	PROPN
admet-505	881	9	.	.	PROPN
admet-505	881	10	shah	shah	PROPN
admet-505	881	11	,	,	PUNCT
admet-505	881	12	j.p	j.p	PROPN
admet-505	881	13	.	.	PROPN
admet-505	881	14	skelly	skelly	PROPN
admet-505	881	15	,	,	PUNCT
admet-505	881	16	g.l	g.l	PROPN
admet-505	881	17	.	.	PROPN
admet-505	881	18	amidon	amidon	PROPN
admet-505	881	19	.	.	PUNCT
admet-505	882	1	drug	drug	PROPN
admet-505	882	2	dissolution	dissolution	NOUN
admet-505	882	3	into	into	ADP
admet-505	882	4	micellar	micellar	ADJ
admet-505	882	5	solutions	solution	NOUN
admet-505	882	6	:	:	PUNCT
admet-505	882	7	development	development	NOUN
admet-505	882	8	of	of	ADP
admet-505	882	9	a	a	DET
admet-505	882	10	convective	convective	ADJ
admet-505	882	11	diffusion	diffusion	NOUN
admet-505	882	12	model	model	NOUN
admet-505	882	13	and	and	CCONJ
admet-505	882	14	comparison	comparison	NOUN
admet-505	882	15	to	to	ADP
admet-505	882	16	the	the	DET
admet-505	882	17	film	film	NOUN
admet-505	882	18	equilibrium	equilibrium	NOUN
admet-505	882	19	model	model	NOUN
admet-505	882	20	with	with	ADP
admet-505	882	21	application	application	NOUN
admet-505	882	22	to	to	ADP
admet-505	882	23	surfactant	surfactant	NOUN
admet-505	882	24	-	-	PUNCT
admet-505	882	25	facilitated	facilitate	VERB
admet-505	882	26	dissolution	dissolution	NOUN
admet-505	882	27	of	of	ADP
admet-505	882	28	carbamazepine	carbamazepine	NOUN
admet-505	882	29	.	.	PUNCT
admet-505	883	1	j.	j.	PROPN
admet-505	883	2	pharm	pharm	PROPN
admet-505	883	3	.	.	PUNCT
admet-505	884	1	sci	sci	PROPN
admet-505	884	2	.	.	PROPN
admet-505	884	3	85	85	NUM
admet-505	884	4	(	(	PUNCT
admet-505	884	5	1996	1996	NUM
admet-505	884	6	)	)	PUNCT
admet-505	884	7	1005	1005	NUM
admet-505	884	8	-	-	SYM
admet-505	884	9	1011	1011	NUM
admet-505	884	10	.	.	PUNCT
admet-505	885	1	[	[	X
admet-505	885	2	33	33	NUM
admet-505	885	3	]	]	PUNCT
admet-505	885	4	m.	m.	NOUN
admet-505	885	5	li	li	PROPN
admet-505	885	6	,	,	PUNCT
admet-505	885	7	n.	n.	PROPN
admet-505	885	8	qiao	qiao	PROPN
admet-505	885	9	,	,	PUNCT
admet-505	885	10	k.	k.	PROPN
admet-505	885	11	wang	wang	PROPN
admet-505	885	12	.	.	PUNCT
admet-505	886	1	influence	influence	NOUN
admet-505	886	2	of	of	ADP
admet-505	886	3	sodium	sodium	NOUN
admet-505	886	4	lauryl	lauryl	NOUN
admet-505	886	5	sulfate	sulfate	NOUN
admet-505	886	6	and	and	CCONJ
admet-505	886	7	tween	tween	NOUN
admet-505	886	8	80	80	NUM
admet-505	886	9	on	on	ADP
admet-505	886	10	carbamazepine	carbamazepine	NOUN
admet-505	886	11	–	–	PUNCT
admet-505	886	12	nicotinamide	nicotinamide	NOUN
admet-505	886	13	cocrystal	cocrystal	ADJ
admet-505	886	14	solubility	solubility	NOUN
admet-505	886	15	and	and	CCONJ
admet-505	886	16	dissolution	dissolution	NOUN
admet-505	886	17	behaviour	behaviour	NOUN
admet-505	886	18	.	.	PUNCT
admet-505	887	1	pharmaceutics	pharmaceutic	NOUN
admet-505	887	2	5	5	NUM
admet-505	887	3	(	(	PUNCT
admet-505	887	4	2013	2013	NUM
admet-505	887	5	)	)	PUNCT
admet-505	887	6	508	508	NUM
admet-505	887	7	-	-	SYM
admet-505	887	8	524	524	NUM
admet-505	887	9	.	.	PUNCT
admet-505	888	1	[	[	X
admet-505	888	2	34	34	NUM
admet-505	888	3	]	]	X
admet-505	888	4	n.	n.	PROPN
admet-505	888	5	ni	ni	PROPN
admet-505	888	6	,	,	PUNCT
admet-505	888	7	t.	t.	PROPN
admet-505	888	8	sanghvi	sanghvi	PROPN
admet-505	888	9	,	,	PUNCT
admet-505	888	10	s.h	s.h	PROPN
admet-505	888	11	.	.	NOUN
admet-505	888	12	yalkowsky	yalkowsky	ADJ
admet-505	888	13	.	.	PUNCT
admet-505	889	1	solubilization	solubilization	NOUN
admet-505	889	2	and	and	CCONJ
admet-505	889	3	preformulation	preformulation	NOUN
admet-505	889	4	of	of	ADP
admet-505	889	5	carbendazim	carbendazim	NOUN
admet-505	889	6	.	.	PUNCT
admet-505	890	1	int	int	NOUN
admet-505	890	2	.	.	PUNCT
admet-505	891	1	j.	j.	PROPN
admet-505	891	2	pharm	pharm	PROPN
admet-505	891	3	.	.	PUNCT
admet-505	892	1	244	244	NUM
admet-505	892	2	(	(	PUNCT
admet-505	892	3	2002	2002	NUM
admet-505	892	4	)	)	PUNCT
admet-505	892	5	99–104	99–104	NOUN
admet-505	892	6	.	.	PUNCT
admet-505	893	1	[	[	X
admet-505	893	2	35	35	NUM
admet-505	893	3	]	]	PUNCT
admet-505	893	4	s.	s.	PROPN
admet-505	893	5	chakraborty	chakraborty	PROPN
admet-505	893	6	,	,	PUNCT
admet-505	893	7	d.	d.	PROPN
admet-505	893	8	shukla	shukla	PROPN
admet-505	893	9	,	,	PUNCT
admet-505	893	10	a.	a.	NOUN
admet-505	893	11	jain	jain	PROPN
admet-505	893	12	,	,	PUNCT
admet-505	893	13	b.	b.	PROPN
admet-505	893	14	mishra	mishra	PROPN
admet-505	893	15	,	,	PUNCT
admet-505	893	16	s.	s.	PROPN
admet-505	893	17	singh	singh	PROPN
admet-505	893	18	.	.	PUNCT
admet-505	894	1	assessment	assessment	NOUN
admet-505	894	2	of	of	ADP
admet-505	894	3	solubilization	solubilization	NOUN
admet-505	894	4	characteristics	characteristic	NOUN
admet-505	894	5	of	of	ADP
admet-505	894	6	different	different	ADJ
admet-505	894	7	surfactants	surfactant	NOUN
admet-505	894	8	for	for	ADP
admet-505	894	9	carvedilol	carvedilol	NOUN
admet-505	894	10	phosphate	phosphate	NOUN
admet-505	894	11	as	as	ADP
admet-505	894	12	a	a	DET
admet-505	894	13	function	function	NOUN
admet-505	894	14	of	of	ADP
admet-505	894	15	ph	ph	PROPN
admet-505	894	16	.	.	PROPN
admet-505	894	17	j.	j.	PROPN
admet-505	894	18	colloid	colloid	PROPN
admet-505	894	19	inter	inter	PROPN
admet-505	894	20	.	.	PUNCT
admet-505	895	1	sci	sci	PROPN
admet-505	895	2	.	.	PROPN
admet-505	895	3	335	335	NUM
admet-505	895	4	(	(	PUNCT
admet-505	895	5	2009	2009	NUM
admet-505	895	6	)	)	PUNCT
admet-505	895	7	242	242	NUM
admet-505	895	8	–	–	PUNCT
admet-505	895	9	249	249	NUM
admet-505	895	10	.	.	PUNCT
admet-505	896	1	[	[	X
admet-505	896	2	36	36	NUM
admet-505	896	3	]	]	PUNCT
admet-505	896	4	s.	s.	PROPN
admet-505	896	5	feng	feng	PROPN
admet-505	896	6	.	.	PUNCT
admet-505	897	1	studies	study	NOUN
admet-505	897	2	on	on	ADP
admet-505	897	3	drug	drug	NOUN
admet-505	897	4	solubilization	solubilization	NOUN
admet-505	897	5	mechanism	mechanism	NOUN
admet-505	897	6	in	in	ADP
admet-505	897	7	simple	simple	ADJ
admet-505	897	8	micelle	micelle	NOUN
admet-505	897	9	systems	system	NOUN
admet-505	897	10	.	.	PUNCT
admet-505	898	1	ph.d	ph.d	PROPN
admet-505	898	2	.	.	PUNCT
admet-505	899	1	thesis	thesis	PROPN
admet-505	899	2	,	,	PUNCT
admet-505	899	3	univ	univ	PROPN
admet-505	899	4	.	.	PUNCT
admet-505	900	1	kentucky	kentucky	PROPN
admet-505	900	2	,	,	PUNCT
admet-505	900	3	2009	2009	NUM
admet-505	900	4	.	.	PUNCT
admet-505	901	1	alex	alex	PROPN
admet-505	901	2	avdeef	avdeef	PROPN
admet-505	901	3	admet	admet	PROPN
admet-505	901	4	&	&	CCONJ
admet-505	901	5	dmpk	dmpk	PROPN
admet-505	901	6	6(2	6(2	NUM
admet-505	901	7	)	)	PUNCT
admet-505	901	8	(	(	PUNCT
admet-505	901	9	2018	2018	NUM
admet-505	901	10	)	)	PUNCT
admet-505	901	11	105	105	NUM
admet-505	901	12	-	-	SYM
admet-505	901	13	139	139	NUM
admet-505	901	14	136	136	NUM
admet-505	901	15	[	[	X
admet-505	901	16	37	37	NUM
admet-505	901	17	]	]	X
admet-505	901	18	p.a	p.a	PROPN
admet-505	901	19	.	.	PROPN
admet-505	901	20	bhat	bhat	PROPN
admet-505	901	21	,	,	PUNCT
admet-505	901	22	a.a	a.a	PROPN
admet-505	901	23	.	.	PROPN
admet-505	901	24	dar	dar	PROPN
admet-505	901	25	,	,	PUNCT
admet-505	901	26	g.m	g.m	PROPN
admet-505	901	27	.	.	PROPN
admet-505	902	1	rather	rather	ADV
admet-505	902	2	.	.	PUNCT
admet-505	903	1	solubilization	solubilization	NOUN
admet-505	903	2	capabilities	capability	NOUN
admet-505	903	3	of	of	ADP
admet-505	903	4	some	some	DET
admet-505	903	5	cationic	cationic	ADJ
admet-505	903	6	,	,	PUNCT
admet-505	903	7	anionic	anionic	ADJ
admet-505	903	8	,	,	PUNCT
admet-505	903	9	and	and	CCONJ
admet-505	903	10	nonionic	nonionic	ADJ
admet-505	903	11	surfactants	surfactant	NOUN
admet-505	903	12	toward	toward	ADP
admet-505	903	13	the	the	DET
admet-505	903	14	poorly	poorly	ADV
admet-505	903	15	water	water	NOUN
admet-505	903	16	-	-	PUNCT
admet-505	903	17	soluble	soluble	ADJ
admet-505	903	18	antibiotic	antibiotic	ADJ
admet-505	903	19	drug	drug	NOUN
admet-505	903	20	erythromycin	erythromycin	PROPN
admet-505	903	21	.	.	PUNCT
admet-505	904	1	j.	j.	PROPN
admet-505	904	2	chem	chem	PROPN
admet-505	904	3	.	.	PUNCT
admet-505	905	1	eng	eng	PROPN
admet-505	905	2	.	.	PROPN
admet-505	906	1	data	data	PROPN
admet-505	906	2	53	53	NUM
admet-505	906	3	(	(	PUNCT
admet-505	906	4	2008	2008	NUM
admet-505	906	5	)	)	PUNCT
admet-505	906	6	1271–1277	1271–1277	NUM
admet-505	906	7	.	.	PUNCT
admet-505	907	1	[	[	X
admet-505	907	2	38	38	NUM
admet-505	907	3	]	]	PUNCT
admet-505	907	4	s.	s.	PROPN
admet-505	907	5	jamzad	jamzad	PROPN
admet-505	907	6	,	,	PUNCT
admet-505	907	7	r.	r.	PROPN
admet-505	907	8	fassihi	fassihi	PROPN
admet-505	907	9	.	.	PUNCT
admet-505	908	1	role	role	NOUN
admet-505	908	2	of	of	ADP
admet-505	908	3	surfactant	surfactant	NOUN
admet-505	908	4	and	and	CCONJ
admet-505	908	5	ph	ph	ADJ
admet-505	908	6	on	on	ADP
admet-505	908	7	dissolution	dissolution	NOUN
admet-505	908	8	properties	property	NOUN
admet-505	908	9	of	of	ADP
admet-505	908	10	fenofibrate	fenofibrate	NOUN
admet-505	908	11	and	and	CCONJ
admet-505	908	12	glipizide	glipizide	ADJ
admet-505	908	13	—	—	PUNCT
admet-505	908	14	a	a	DET
admet-505	908	15	technical	technical	ADJ
admet-505	908	16	note	note	NOUN
admet-505	908	17	.	.	PUNCT
admet-505	909	1	aaps	aap	NOUN
admet-505	909	2	pharmscitech	pharmscitech	VERB
admet-505	909	3	7	7	NUM
admet-505	909	4	(	(	PUNCT
admet-505	909	5	2006	2006	NUM
admet-505	909	6	)	)	PUNCT
admet-505	909	7	e1	e1	NOUN
admet-505	909	8	-	-	PUNCT
admet-505	909	9	e6	e6	NOUN
admet-505	909	10	.	.	PUNCT
admet-505	910	1	[	[	X
admet-505	910	2	39	39	NUM
admet-505	910	3	]	]	X
admet-505	910	4	n.	n.	PROPN
admet-505	910	5	seedher	seedher	PROPN
admet-505	910	6	,	,	PUNCT
admet-505	910	7	m.	m.	NOUN
admet-505	910	8	kanojia	kanojia	PROPN
admet-505	910	9	.	.	PUNCT
admet-505	910	10	micellar	micellar	ADJ
admet-505	910	11	solubilization	solubilization	NOUN
admet-505	910	12	of	of	ADP
admet-505	910	13	some	some	DET
admet-505	910	14	poorly	poorly	ADV
admet-505	910	15	soluble	soluble	ADJ
admet-505	910	16	antidiabetic	antidiabetic	ADJ
admet-505	910	17	drugs	drug	NOUN
admet-505	910	18	:	:	PUNCT
admet-505	910	19	a	a	DET
admet-505	910	20	technical	technical	ADJ
admet-505	910	21	note	note	NOUN
admet-505	910	22	.	.	PUNCT
admet-505	911	1	aaps	aap	NOUN
admet-505	911	2	pharmscitech	pharmscitech	VERB
admet-505	911	3	9	9	NUM
admet-505	911	4	(	(	PUNCT
admet-505	911	5	2008	2008	NUM
admet-505	911	6	)	)	PUNCT
admet-505	911	7	431	431	NUM
admet-505	911	8	-	-	SYM
admet-505	911	9	436	436	NUM
admet-505	911	10	.	.	PUNCT
admet-505	912	1	[	[	X
admet-505	912	2	40	40	NUM
admet-505	912	3	]	]	X
admet-505	912	4	k.a	k.a	PROPN
admet-505	912	5	.	.	PROPN
admet-505	912	6	johnson	johnson	PROPN
admet-505	912	7	,	,	PUNCT
admet-505	912	8	g.b	g.b	PROPN
admet-505	912	9	.	.	PROPN
admet-505	912	10	westerman	westerman	PROPN
admet-505	912	11	-	-	PUNCT
admet-505	912	12	clark	clark	PROPN
admet-505	912	13	,	,	PUNCT
admet-505	912	14	d.o	d.o	PROPN
admet-505	912	15	.	.	PROPN
admet-505	912	16	shah	shah	PROPN
admet-505	912	17	.	.	PUNCT
admet-505	913	1	transport	transport	NOUN
admet-505	913	2	of	of	ADP
admet-505	913	3	micelle	micelle	NOUN
admet-505	913	4	-	-	PUNCT
admet-505	913	5	solubilized	solubilize	VERB
admet-505	913	6	steroids	steroid	NOUN
admet-505	913	7	across	across	ADP
admet-505	913	8	microporous	microporous	ADJ
admet-505	913	9	membranes	membrane	NOUN
admet-505	913	10	.	.	PUNCT
admet-505	914	1	j.	j.	PROPN
admet-505	914	2	pharm	pharm	PROPN
admet-505	914	3	.	.	PUNCT
admet-505	915	1	sci	sci	PROPN
admet-505	915	2	.	.	PROPN
admet-505	916	1	76	76	NUM
admet-505	916	2	(	(	PUNCT
admet-505	916	3	1987	1987	NUM
admet-505	916	4	)	)	PUNCT
admet-505	916	5	277	277	NUM
admet-505	916	6	-	-	PUNCT
admet-505	916	7	285	285	NUM
admet-505	916	8	.	.	PUNCT
admet-505	917	1	[	[	X
admet-505	917	2	41	41	NUM
admet-505	917	3	]	]	PUNCT
admet-505	917	4	s.-h	s.-h	NOUN
admet-505	917	5	.	.	PUNCT
admet-505	918	1	park	park	NOUN
admet-505	918	2	,	,	PUNCT
admet-505	918	3	h.-k	h.-k	PROPN
admet-505	918	4	.	.	PUNCT
admet-505	919	1	choi	choi	NOUN
admet-505	919	2	.	.	PUNCT
admet-505	920	1	the	the	DET
admet-505	920	2	effects	effect	NOUN
admet-505	920	3	of	of	ADP
admet-505	920	4	surfactants	surfactant	NOUN
admet-505	920	5	on	on	ADP
admet-505	920	6	the	the	DET
admet-505	920	7	dissolution	dissolution	ADJ
admet-505	920	8	profiles	profile	NOUN
admet-505	920	9	of	of	ADP
admet-505	920	10	poorly	poorly	ADV
admet-505	920	11	water	water	NOUN
admet-505	920	12	-	-	PUNCT
admet-505	920	13	soluble	soluble	ADJ
admet-505	920	14	acidic	acidic	ADJ
admet-505	920	15	drugs	drug	NOUN
admet-505	920	16	.	.	PUNCT
admet-505	921	1	int	int	NOUN
admet-505	921	2	.	.	PUNCT
admet-505	922	1	j.	j.	PROPN
admet-505	922	2	pharm	pharm	PROPN
admet-505	922	3	.	.	PUNCT
admet-505	923	1	321	321	NUM
admet-505	923	2	(	(	PUNCT
admet-505	923	3	2006	2006	NUM
admet-505	923	4	)	)	PUNCT
admet-505	923	5	35–41	35–41	NUM
admet-505	923	6	.	.	PUNCT
admet-505	924	1	[	[	X
admet-505	924	2	42	42	NUM
admet-505	924	3	]	]	X
admet-505	924	4	c.o	c.o	PROPN
admet-505	924	5	.	.	PROPN
admet-505	924	6	rangel	rangel	PROPN
admet-505	924	7	-	-	PUNCT
admet-505	924	8	yagui	yagui	NOUN
admet-505	924	9	,	,	PUNCT
admet-505	924	10	h.w.l	h.w.l	NOUN
admet-505	924	11	.	.	PUNCT
admet-505	924	12	hsu	hsu	PROPN
admet-505	924	13	,	,	PUNCT
admet-505	924	14	a.	a.	NOUN
admet-505	924	15	pessoa	pessoa	NOUN
admet-505	924	16	,	,	PUNCT
admet-505	924	17	jr	jr	PROPN
admet-505	924	18	.	.	PROPN
admet-505	924	19	,	,	PUNCT
admet-505	924	20	l.c	l.c	PROPN
admet-505	924	21	.	.	PROPN
admet-505	924	22	tavares	tavare	NOUN
admet-505	924	23	.	.	PUNCT
admet-505	925	1	micellar	micellar	ADJ
admet-505	925	2	solubilization	solubilization	NOUN
admet-505	925	3	of	of	ADP
admet-505	925	4	ibuprofen	ibuprofen	NOUN
admet-505	925	5	–	–	PUNCT
admet-505	925	6	influence	influence	NOUN
admet-505	925	7	of	of	ADP
admet-505	925	8	surfactant	surfactant	ADJ
admet-505	925	9	head	head	NOUN
admet-505	925	10	groups	group	NOUN
admet-505	925	11	on	on	ADP
admet-505	925	12	the	the	DET
admet-505	925	13	extent	extent	NOUN
admet-505	925	14	of	of	ADP
admet-505	925	15	solubilization	solubilization	NOUN
admet-505	925	16	.	.	PUNCT
admet-505	926	1	brazilian	brazilian	ADJ
admet-505	926	2	j.	j.	PROPN
admet-505	926	3	pharm	pharm	PROPN
admet-505	926	4	.	.	PUNCT
admet-505	927	1	sci	sci	PROPN
admet-505	927	2	.	.	PROPN
admet-505	928	1	41	41	NUM
admet-505	928	2	(	(	PUNCT
admet-505	928	3	2005	2005	NUM
admet-505	928	4	)	)	PUNCT
admet-505	928	5	237	237	NUM
admet-505	928	6	-	-	SYM
admet-505	928	7	246	246	NUM
admet-505	928	8	.	.	PUNCT
admet-505	929	1	[	[	X
admet-505	929	2	43	43	NUM
admet-505	929	3	]	]	X
admet-505	929	4	s.d	s.d	PROPN
admet-505	929	5	.	.	PROPN
admet-505	929	6	bhattamishra	bhattamishra	PROPN
admet-505	929	7	,	,	PUNCT
admet-505	929	8	r.k	r.k	PROPN
admet-505	929	9	.	.	PROPN
admet-505	929	10	padhy	padhy	PROPN
admet-505	929	11	.	.	PUNCT
admet-505	930	1	estimation	estimation	NOUN
admet-505	930	2	of	of	ADP
admet-505	930	3	ibuprofen	ibuprofen	NOUN
admet-505	930	4	solubilization	solubilization	NOUN
admet-505	930	5	in	in	ADP
admet-505	930	6	cationic	cationic	ADJ
admet-505	930	7	and	and	CCONJ
admet-505	930	8	anionic	anionic	ADJ
admet-505	930	9	surfactant	surfactant	NOUN
admet-505	930	10	media	medium	NOUN
admet-505	930	11	:	:	PUNCT
admet-505	930	12	application	application	NOUN
admet-505	930	13	of	of	ADP
admet-505	930	14	micelle	micelle	NOUN
admet-505	930	15	binding	bind	VERB
admet-505	930	16	model	model	NOUN
admet-505	930	17	.	.	PUNCT
admet-505	931	1	indian	indian	PROPN
admet-505	931	2	j.	j.	PROPN
admet-505	931	3	chem	chem	PROPN
admet-505	931	4	.	.	PUNCT
admet-505	932	1	tehnol	tehnol	NOUN
admet-505	932	2	.	.	PUNCT
admet-505	933	1	16	16	NUM
admet-505	933	2	(	(	PUNCT
admet-505	933	3	2009	2009	NUM
admet-505	933	4	)	)	PUNCT
admet-505	933	5	426	426	NUM
admet-505	933	6	-	-	SYM
admet-505	933	7	430	430	NUM
admet-505	933	8	.	.	PUNCT
admet-505	934	1	[	[	X
admet-505	934	2	44	44	NUM
admet-505	934	3	]	]	PUNCT
admet-505	934	4	d.	d.	PROPN
admet-505	934	5	bolten	bolten	PROPN
admet-505	934	6	,	,	PUNCT
admet-505	934	7	r.	r.	PROPN
admet-505	934	8	lietzow	lietzow	PROPN
admet-505	934	9	,	,	PUNCT
admet-505	934	10	m.	m.	NOUN
admet-505	934	11	türk	türk	PROPN
admet-505	934	12	.	.	PUNCT
admet-505	935	1	solubility	solubility	NOUN
admet-505	935	2	of	of	ADP
admet-505	935	3	ibuprofen	ibuprofen	NOUN
admet-505	935	4	,	,	PUNCT
admet-505	935	5	phytosterol	phytosterol	NOUN
admet-505	935	6	,	,	PUNCT
admet-505	935	7	salicylic	salicylic	ADJ
admet-505	935	8	acid	acid	NOUN
admet-505	935	9	,	,	PUNCT
admet-505	935	10	and	and	CCONJ
admet-505	935	11	naproxen	naproxen	NOUN
admet-505	935	12	in	in	ADP
admet-505	935	13	aqueous	aqueous	ADJ
admet-505	935	14	solutions	solution	NOUN
admet-505	935	15	.	.	PUNCT
admet-505	936	1	chem	chem	NOUN
admet-505	936	2	.	.	PUNCT
admet-505	937	1	eng	eng	PROPN
admet-505	937	2	.	.	PROPN
admet-505	938	1	technol	technol	PROPN
admet-505	938	2	.	.	PUNCT
admet-505	939	1	36	36	NUM
admet-505	939	2	(	(	PUNCT
admet-505	939	3	2013	2013	NUM
admet-505	939	4	)	)	PUNCT
admet-505	940	1	426–434	426–434	NUM
admet-505	940	2	.	.	PUNCT
admet-505	941	1	[	[	X
admet-505	941	2	45	45	NUM
admet-505	941	3	]	]	SYM
admet-505	941	4	n.m	n.m	PROPN
admet-505	941	5	.	.	PROPN
admet-505	941	6	najib	najib	PROPN
admet-505	941	7	,	,	PUNCT
admet-505	941	8	m.s	m.s	PROPN
admet-505	941	9	.	.	PROPN
admet-505	941	10	suleiman	suleiman	PROPN
admet-505	941	11	.	.	PUNCT
admet-505	942	1	the	the	DET
admet-505	942	2	effect	effect	NOUN
admet-505	942	3	of	of	ADP
admet-505	942	4	hydrophilic	hydrophilic	ADJ
admet-505	942	5	polymers	polymer	NOUN
admet-505	942	6	and	and	CCONJ
admet-505	942	7	surface	surface	VERB
admet-505	942	8	active	active	ADJ
admet-505	942	9	agents	agent	NOUN
admet-505	942	10	on	on	ADP
admet-505	942	11	the	the	DET
admet-505	942	12	solubility	solubility	NOUN
admet-505	942	13	of	of	ADP
admet-505	942	14	indomethacin	indomethacin	PROPN
admet-505	942	15	.	.	PUNCT
admet-505	943	1	int	int	NOUN
admet-505	943	2	.	.	PUNCT
admet-505	944	1	j.	j.	PROPN
admet-505	944	2	pharm	pharm	PROPN
admet-505	944	3	.	.	PUNCT
admet-505	945	1	24	24	NUM
admet-505	945	2	(	(	PUNCT
admet-505	945	3	1985	1985	NUM
admet-505	945	4	)	)	PUNCT
admet-505	945	5	165	165	NUM
admet-505	945	6	-	-	SYM
admet-505	945	7	171	171	NUM
admet-505	945	8	.	.	PUNCT
admet-505	946	1	[	[	X
admet-505	946	2	46	46	NUM
admet-505	946	3	]	]	X
admet-505	946	4	j.j	j.j	PROPN
admet-505	946	5	.	.	PROPN
admet-505	946	6	sheng	sheng	PROPN
admet-505	946	7	,	,	PUNCT
admet-505	946	8	n.a	n.a	PROPN
admet-505	946	9	.	.	PROPN
admet-505	946	10	kasim	kasim	PROPN
admet-505	946	11	,	,	PUNCT
admet-505	946	12	r.	r.	PROPN
admet-505	946	13	chandrasekharan	chandrasekharan	PROPN
admet-505	946	14	,	,	PUNCT
admet-505	946	15	g.l	g.l	PROPN
admet-505	946	16	.	.	PROPN
admet-505	946	17	amidon	amidon	PROPN
admet-505	946	18	.	.	PUNCT
admet-505	947	1	solubilization	solubilization	NOUN
admet-505	947	2	and	and	CCONJ
admet-505	947	3	dissolution	dissolution	NOUN
admet-505	947	4	of	of	ADP
admet-505	947	5	insoluble	insoluble	ADJ
admet-505	947	6	weak	weak	ADJ
admet-505	947	7	acid	acid	NOUN
admet-505	947	8	,	,	PUNCT
admet-505	947	9	ketoprofen	ketoprofen	VERB
admet-505	947	10	:	:	PUNCT
admet-505	947	11	effect	effect	NOUN
admet-505	947	12	of	of	ADP
admet-505	947	13	ph	ph	NOUN
admet-505	947	14	combined	combine	VERB
admet-505	947	15	with	with	ADP
admet-505	947	16	surfactant	surfactant	NOUN
admet-505	947	17	.	.	PUNCT
admet-505	948	1	eur	eur	PROPN
admet-505	948	2	.	.	PUNCT
admet-505	949	1	j.	j.	PROPN
admet-505	949	2	pharm	pharm	PROPN
admet-505	949	3	.	.	PUNCT
admet-505	950	1	sci	sci	PROPN
admet-505	950	2	.	.	PROPN
admet-505	950	3	29	29	NUM
admet-505	950	4	(	(	PUNCT
admet-505	950	5	2006	2006	NUM
admet-505	950	6	)	)	PUNCT
admet-505	950	7	306	306	NUM
admet-505	950	8	-	-	SYM
admet-505	950	9	314	314	NUM
admet-505	950	10	.	.	PUNCT
admet-505	951	1	[	[	X
admet-505	951	2	47	47	NUM
admet-505	951	3	]	]	X
admet-505	951	4	g.	g.	PROPN
admet-505	951	5	popović	popović	PROPN
admet-505	951	6	,	,	PUNCT
admet-505	951	7	m.	m.	NOUN
admet-505	951	8	čakar	čakar	PROPN
admet-505	951	9	,	,	PUNCT
admet-505	951	10	d.	d.	PROPN
admet-505	951	11	agbaba	agbaba	PROPN
admet-505	951	12	.	.	PUNCT
admet-505	952	1	acid	acid	ADJ
admet-505	952	2	–	–	PUNCT
admet-505	952	3	base	base	NOUN
admet-505	952	4	equilibria	equilibrium	NOUN
admet-505	952	5	and	and	CCONJ
admet-505	952	6	solubility	solubility	NOUN
admet-505	952	7	of	of	ADP
admet-505	952	8	loratadine	loratadine	NOUN
admet-505	952	9	and	and	CCONJ
admet-505	952	10	desloratadine	desloratadine	NOUN
admet-505	952	11	in	in	ADP
admet-505	952	12	water	water	NOUN
admet-505	952	13	and	and	CCONJ
admet-505	952	14	micellar	micellar	ADJ
admet-505	952	15	media	medium	NOUN
admet-505	952	16	.	.	PUNCT
admet-505	953	1	j.	j.	PROPN
admet-505	953	2	pharm	pharm	PROPN
admet-505	953	3	.	.	PUNCT
admet-505	953	4	biomed	biome	VERB
admet-505	953	5	.	.	PUNCT
admet-505	954	1	anal	anal	ADJ
admet-505	954	2	.	.	PUNCT
admet-505	955	1	49	49	NUM
admet-505	955	2	(	(	PUNCT
admet-505	955	3	2009	2009	NUM
admet-505	955	4	)	)	PUNCT
admet-505	955	5	42	42	NUM
admet-505	955	6	-	-	SYM
admet-505	955	7	47	47	NUM
admet-505	955	8	.	.	PUNCT
admet-505	956	1	[	[	X
admet-505	956	2	48	48	NUM
admet-505	956	3	]	]	PUNCT
admet-505	956	4	g.	g.	PROPN
admet-505	956	5	yang	yang	PROPN
admet-505	956	6	,	,	PUNCT
admet-505	956	7	n.	n.	PROPN
admet-505	956	8	jain	jain	PROPN
admet-505	956	9	,	,	PUNCT
admet-505	956	10	s.h	s.h	PROPN
admet-505	956	11	.	.	NOUN
admet-505	956	12	yalkowsky	yalkowsky	NOUN
admet-505	956	13	.	.	PUNCT
admet-505	957	1	combined	combined	ADJ
admet-505	957	2	effect	effect	NOUN
admet-505	957	3	of	of	ADP
admet-505	957	4	sls	sls	PROPN
admet-505	957	5	and	and	CCONJ
admet-505	957	6	(	(	PUNCT
admet-505	957	7	sbe)7m	sbe)7m	ADJ
admet-505	957	8	-	-	PUNCT
admet-505	957	9	β	β	NOUN
admet-505	957	10	-	-	NOUN
admet-505	957	11	cd	cd	NOUN
admet-505	957	12	on	on	ADP
admet-505	957	13	the	the	DET
admet-505	957	14	solubilization	solubilization	NOUN
admet-505	957	15	of	of	ADP
admet-505	957	16	nsc639829	nsc639829	NOUN
admet-505	957	17	.	.	PUNCT
admet-505	958	1	int	int	NOUN
admet-505	958	2	.	.	PUNCT
admet-505	959	1	j.	j.	PROPN
admet-505	959	2	pharm	pharm	PROPN
admet-505	959	3	.	.	PUNCT
admet-505	960	1	269	269	NUM
admet-505	960	2	(	(	PUNCT
admet-505	960	3	2004	2004	NUM
admet-505	960	4	)	)	PUNCT
admet-505	960	5	141–148	141–148	NUM
admet-505	960	6	.	.	PUNCT
admet-505	961	1	[	[	X
admet-505	961	2	49	49	NUM
admet-505	961	3	]	]	PUNCT
admet-505	961	4	a.	a.	NOUN
admet-505	961	5	jain	jain	PROPN
admet-505	961	6	,	,	PUNCT
admet-505	961	7	y.	y.	PROPN
admet-505	961	8	ran	run	VERB
admet-505	961	9	,	,	PUNCT
admet-505	961	10	s.h	s.h	PROPN
admet-505	961	11	.	.	NOUN
admet-505	961	12	yalkowsky	yalkowsky	ADJ
admet-505	961	13	.	.	PUNCT
admet-505	962	1	effect	effect	NOUN
admet-505	962	2	of	of	ADP
admet-505	962	3	ph	ph	ADJ
admet-505	962	4	-	-	PUNCT
admet-505	962	5	sodium	sodium	NOUN
admet-505	962	6	lauryl	lauryl	NOUN
admet-505	962	7	sulfate	sulfate	NOUN
admet-505	962	8	combination	combination	NOUN
admet-505	962	9	on	on	ADP
admet-505	962	10	solubilization	solubilization	NOUN
admet-505	962	11	of	of	ADP
admet-505	962	12	pg300995	pg300995	NOUN
admet-505	962	13	(	(	PUNCT
admet-505	962	14	an	an	DET
admet-505	962	15	anti	anti	ADJ
admet-505	962	16	-	-	ADJ
admet-505	962	17	hiv	hiv	ADJ
admet-505	962	18	agent	agent	NOUN
admet-505	962	19	):	):	PUNCT
admet-505	962	20	a	a	DET
admet-505	962	21	technical	technical	ADJ
admet-505	962	22	note	note	NOUN
admet-505	962	23	.	.	PUNCT
admet-505	963	1	aaps	aap	NOUN
admet-505	963	2	pharmscitech	pharmscitech	VERB
admet-505	963	3	5	5	NUM
admet-505	963	4	(	(	PUNCT
admet-505	963	5	2004	2004	NUM
admet-505	963	6	)	)	PUNCT
admet-505	963	7	1	1	NUM
admet-505	963	8	-	-	SYM
admet-505	963	9	3	3	NUM
admet-505	963	10	(	(	PUNCT
admet-505	963	11	article	article	NOUN
admet-505	963	12	45	45	NUM
admet-505	963	13	)	)	PUNCT
admet-505	963	14	.	.	PUNCT
admet-505	964	1	[	[	X
admet-505	964	2	50	50	NUM
admet-505	964	3	]	]	PUNCT
admet-505	964	4	k.	k.	PROPN
admet-505	964	5	kawakami	kawakami	PROPN
admet-505	964	6	,	,	PUNCT
admet-505	964	7	n.	n.	PROPN
admet-505	964	8	oda	oda	PROPN
admet-505	964	9	,	,	PUNCT
admet-505	964	10	k.	k.	PROPN
admet-505	964	11	miyoshi	miyoshi	PROPN
admet-505	964	12	,	,	PUNCT
admet-505	964	13	t.	t.	PROPN
admet-505	964	14	funaki	funaki	PROPN
admet-505	964	15	,	,	PUNCT
admet-505	964	16	y.	y.	PROPN
admet-505	964	17	ida	ida	PROPN
admet-505	964	18	.	.	PUNCT
admet-505	965	1	solubilization	solubilization	PROPN
admet-505	965	2	behavior	behavior	NOUN
admet-505	965	3	of	of	ADP
admet-505	965	4	a	a	DET
admet-505	965	5	poorly	poorly	ADV
admet-505	965	6	soluble	soluble	ADJ
admet-505	965	7	drug	drug	NOUN
admet-505	965	8	under	under	ADP
admet-505	965	9	combined	combine	VERB
admet-505	965	10	use	use	NOUN
admet-505	965	11	of	of	ADP
admet-505	965	12	surfactants	surfactant	NOUN
admet-505	965	13	and	and	CCONJ
admet-505	965	14	cosolvents	cosolvent	NOUN
admet-505	965	15	.	.	PUNCT
admet-505	966	1	eur	eur	PROPN
admet-505	966	2	.	.	PUNCT
admet-505	967	1	j.	j.	PROPN
admet-505	967	2	pharm	pharm	PROPN
admet-505	967	3	.	.	PUNCT
admet-505	968	1	sci	sci	PROPN
admet-505	968	2	.	.	PROPN
admet-505	968	3	28	28	NUM
admet-505	968	4	(	(	PUNCT
admet-505	968	5	2006	2006	NUM
admet-505	968	6	)	)	PUNCT
admet-505	968	7	7	7	NUM
admet-505	968	8	-	-	SYM
admet-505	968	9	14	14	NUM
admet-505	968	10	.	.	PUNCT
admet-505	969	1	[	[	X
admet-505	969	2	51	51	NUM
admet-505	969	3	]	]	PUNCT
admet-505	969	4	j.	j.	PROPN
admet-505	969	5	jinno	jinno	PROPN
admet-505	969	6	,	,	PUNCT
admet-505	969	7	d.-m	d.-m	PROPN
admet-505	969	8	.	.	PUNCT
admet-505	970	1	oh	oh	INTJ
admet-505	970	2	,	,	PUNCT
admet-505	970	3	j.r	j.r	PROPN
admet-505	970	4	.	.	PROPN
admet-505	970	5	crison	crison	PROPN
admet-505	970	6	,	,	PUNCT
admet-505	970	7	g.l	g.l	PROPN
admet-505	970	8	.	.	PROPN
admet-505	970	9	amidon	amidon	PROPN
admet-505	970	10	.	.	PUNCT
admet-505	971	1	dissolution	dissolution	NOUN
admet-505	971	2	of	of	ADP
admet-505	971	3	ionizable	ionizable	ADJ
admet-505	971	4	water	water	NOUN
admet-505	971	5	-	-	PUNCT
admet-505	971	6	insoluble	insoluble	ADJ
admet-505	971	7	drugs	drug	NOUN
admet-505	971	8	:	:	PUNCT
admet-505	971	9	the	the	DET
admet-505	971	10	combined	combined	ADJ
admet-505	971	11	effect	effect	NOUN
admet-505	971	12	of	of	ADP
admet-505	971	13	ph	ph	NOUN
admet-505	971	14	and	and	CCONJ
admet-505	971	15	surfactant	surfactant	NOUN
admet-505	971	16	.	.	PUNCT
admet-505	972	1	j.	j.	PROPN
admet-505	972	2	pharm	pharm	PROPN
admet-505	972	3	.	.	PUNCT
admet-505	973	1	sci	sci	PROPN
admet-505	973	2	.	.	PROPN
admet-505	973	3	89	89	NUM
admet-505	973	4	(	(	PUNCT
admet-505	973	5	2000	2000	NUM
admet-505	973	6	)	)	PUNCT
admet-505	973	7	268	268	NUM
admet-505	973	8	-	-	SYM
admet-505	973	9	274	274	NUM
admet-505	973	10	.	.	PUNCT
admet-505	974	1	[	[	X
admet-505	974	2	52	52	NUM
admet-505	974	3	]	]	PUNCT
admet-505	974	4	j.	j.	PROPN
admet-505	974	5	cvejić	cvejić	PROPN
admet-505	974	6	,	,	PUNCT
admet-505	974	7	m.	m.	NOUN
admet-505	974	8	poša	poša	PROPN
admet-505	974	9	,	,	PUNCT
admet-505	974	10	a.	a.	PROPN
admet-505	974	11	sebenji	sebenji	PROPN
admet-505	974	12	,	,	PUNCT
admet-505	974	13	m.	m.	NOUN
admet-505	974	14	atanacković	atanacković	PROPN
admet-505	974	15	.	.	PUNCT
admet-505	975	1	comparison	comparison	NOUN
admet-505	975	2	of	of	ADP
admet-505	975	3	solubilization	solubilization	NOUN
admet-505	975	4	capacity	capacity	NOUN
admet-505	975	5	of	of	ADP
admet-505	975	6	resveratrol	resveratrol	NOUN
admet-505	975	7	in	in	ADP
admet-505	975	8	sodium	sodium	NOUN
admet-505	975	9	3α,12α	3α,12α	NUM
admet-505	975	10	-	-	PUNCT
admet-505	975	11	dihydroxy-7	dihydroxy-7	NUM
admet-505	975	12	-	-	PUNCT
admet-505	975	13	oxo-5β	oxo-5β	NOUN
admet-505	975	14	-	-	PUNCT
admet-505	975	15	cholanoate	cholanoate	NOUN
admet-505	975	16	and	and	CCONJ
admet-505	975	17	sodium	sodium	NOUN
admet-505	975	18	dodecyl	dodecyl	PROPN
admet-505	975	19	sulfate	sulfate	NOUN
admet-505	975	20	.	.	PUNCT
admet-505	976	1	sci	sci	PROPN
admet-505	976	2	.	.	PROPN
admet-505	976	3	world	world	PROPN
admet-505	976	4	j.	j.	PROPN
admet-505	976	5	,	,	PUNCT
admet-505	976	6	vol	vol	NOUN
admet-505	976	7	.	.	PROPN
admet-505	976	8	2014	2014	NUM
admet-505	976	9	,	,	PUNCT
admet-505	976	10	article	article	NOUN
admet-505	976	11	i	i	PROPN
admet-505	976	12	d	d	PROPN
admet-505	976	13	265953	265953	NUM
admet-505	976	14	,	,	PUNCT
admet-505	976	15	7	7	NUM
admet-505	976	16	pages	page	NOUN
admet-505	976	17	,	,	PUNCT
admet-505	976	18	doi.org/10.1155/2014/265953	doi.org/10.1155/2014/265953	PROPN
admet-505	976	19	.	.	PUNCT
admet-505	977	1	[	[	X
admet-505	977	2	53	53	NUM
admet-505	977	3	]	]	PUNCT
admet-505	977	4	l.	l.	PROPN
admet-505	977	5	stopková	stopková	PROPN
admet-505	977	6	,	,	PUNCT
admet-505	977	7	a.	a.	PROPN
admet-505	977	8	hriňaková	hriňaková	PROPN
admet-505	977	9	,	,	PUNCT
admet-505	977	10	ž	ž	PROPN
admet-505	977	11	.	.	PROPN
admet-505	977	12	bezáková	bezáková	PROPN
admet-505	977	13	,	,	PUNCT
admet-505	977	14	j.	j.	PROPN
admet-505	977	15	oremusová	oremusová	PROPN
admet-505	977	16	,	,	PUNCT
admet-505	977	17	f.	f.	PROPN
admet-505	977	18	andriamanty	andriamanty	PROPN
admet-505	977	19	,	,	PUNCT
admet-505	977	20	v.	v.	ADP
admet-505	977	21	žufková	žufková	PROPN
admet-505	977	22	.	.	PUNCT
admet-505	978	1	influence	influence	NOUN
admet-505	978	2	of	of	ADP
admet-505	978	3	valsartan	valsartan	PROPN
admet-505	978	4	on	on	ADP
admet-505	978	5	the	the	DET
admet-505	978	6	thermodynamics	thermodynamic	NOUN
admet-505	978	7	of	of	ADP
admet-505	978	8	micellization	micellization	NOUN
admet-505	978	9	of	of	ADP
admet-505	978	10	anionic	anionic	ADJ
admet-505	978	11	surfactant	surfactant	ADJ
admet-505	978	12	sodium	sodium	NOUN
admet-505	978	13	dodecyl	dodecyl	PROPN
admet-505	978	14	sulphate	sulphate	NOUN
admet-505	978	15	.	.	PUNCT
admet-505	979	1	eur	eur	PROPN
admet-505	979	2	.	.	PUNCT
admet-505	979	3	pharm	pharm	PROPN
admet-505	979	4	.	.	PUNCT
admet-505	980	1	j.	j.	PROPN
admet-505	980	2	63	63	NUM
admet-505	980	3	(	(	PUNCT
admet-505	980	4	2016	2016	NUM
admet-505	980	5	)	)	PUNCT
admet-505	980	6	30	30	NUM
admet-505	980	7	-	-	SYM
admet-505	980	8	36	36	NUM
admet-505	980	9	.	.	PUNCT
admet-505	981	1	[	[	X
admet-505	981	2	54	54	NUM
admet-505	981	3	]	]	X
admet-505	981	4	s.h	s.h	PROPN
admet-505	981	5	.	.	NOUN
admet-505	981	6	yalkowsky	yalkowsky	ADJ
admet-505	981	7	,	,	PUNCT
admet-505	981	8	y.	y.	PROPN
admet-505	981	9	he	he	PRON
admet-505	981	10	,	,	PUNCT
admet-505	981	11	p.	p.	PROPN
admet-505	981	12	jain	jain	PROPN
admet-505	981	13	.	.	PUNCT
admet-505	982	1	handbook	handbook	NOUN
admet-505	982	2	of	of	ADP
admet-505	982	3	aqueous	aqueous	ADJ
admet-505	982	4	solubility	solubility	NOUN
admet-505	982	5	data	datum	NOUN
admet-505	982	6	.	.	PUNCT
admet-505	983	1	second	second	PROPN
admet-505	983	2	edition	edition	PROPN
admet-505	983	3	.	.	PUNCT
admet-505	984	1	crc	crc	PROPN
admet-505	984	2	press	press	PROPN
admet-505	984	3	taylor	taylor	PROPN
admet-505	984	4	&	&	CCONJ
admet-505	984	5	francis	francis	PROPN
admet-505	984	6	group	group	PROPN
admet-505	984	7	,	,	PUNCT
admet-505	984	8	boca	boca	PROPN
admet-505	984	9	raton	raton	PROPN
admet-505	984	10	,	,	PUNCT
admet-505	984	11	fl	fl	PROPN
admet-505	984	12	,	,	PUNCT
admet-505	984	13	2010	2010	NUM
admet-505	984	14	.	.	PUNCT
admet-505	985	1	[	[	X
admet-505	985	2	55	55	NUM
admet-505	985	3	]	]	PUNCT
admet-505	985	4	a.	a.	NOUN
admet-505	985	5	avdeef	avdeef	PROPN
admet-505	985	6	.	.	PUNCT
admet-505	986	1	suggested	suggest	VERB
admet-505	986	2	improvements	improvement	NOUN
admet-505	986	3	for	for	ADP
admet-505	986	4	measurement	measurement	NOUN
admet-505	986	5	of	of	ADP
admet-505	986	6	equilibrium	equilibrium	NOUN
admet-505	986	7	solubility	solubility	NOUN
admet-505	986	8	-	-	PUNCT
admet-505	986	9	ph	ph	NOUN
admet-505	986	10	of	of	ADP
admet-505	986	11	ionizable	ionizable	ADJ
admet-505	986	12	drugs	drug	NOUN
admet-505	986	13	.	.	PUNCT
admet-505	987	1	admet	admet	PROPN
admet-505	987	2	&	&	CCONJ
admet-505	987	3	dmpk	dmpk	PROPN
admet-505	987	4	3	3	NUM
admet-505	987	5	(	(	PUNCT
admet-505	987	6	2015	2015	NUM
admet-505	987	7	)	)	PUNCT
admet-505	987	8	84	84	NUM
admet-505	987	9	-	-	SYM
admet-505	987	10	109	109	NUM
admet-505	987	11	.	.	PUNCT
admet-505	988	1	[	[	X
admet-505	988	2	56	56	NUM
admet-505	988	3	]	]	PUNCT
admet-505	988	4	a.	a.	NOUN
admet-505	988	5	avdeef	avdeef	PROPN
admet-505	988	6	,	,	PUNCT
admet-505	988	7	e.	e.	PROPN
admet-505	988	8	fuguet	fuguet	PROPN
admet-505	988	9	,	,	PUNCT
admet-505	988	10	a.	a.	PROPN
admet-505	988	11	llinàs	llinàs	PROPN
admet-505	988	12	,	,	PUNCT
admet-505	988	13	c.	c.	PROPN
admet-505	988	14	ràfols	ràfols	PROPN
admet-505	988	15	,	,	PUNCT
admet-505	988	16	e.	e.	PROPN
admet-505	988	17	bosch	bosch	PROPN
admet-505	988	18	,	,	PUNCT
admet-505	988	19	g.	g.	PROPN
admet-505	988	20	völgyi	völgyi	PROPN
admet-505	988	21	,	,	PUNCT
admet-505	988	22	t.	t.	NOUN
admet-505	988	23	verbić	verbić	PROPN
admet-505	988	24	,	,	PUNCT
admet-505	988	25	e.	e.	PROPN
admet-505	988	26	boldyreva	boldyreva	PROPN
admet-505	988	27	,	,	PUNCT
admet-505	988	28	k.	k.	PROPN
admet-505	988	29	takács	takács	PROPN
admet-505	988	30	-	-	PUNCT
admet-505	988	31	novák	novák	PROPN
admet-505	988	32	.	.	PUNCT
admet-505	988	33	equilibrium	equilibrium	NOUN
admet-505	988	34	solubility	solubility	NOUN
admet-505	988	35	measurement	measurement	NOUN
admet-505	988	36	of	of	ADP
admet-505	988	37	ionizable	ionizable	ADJ
admet-505	988	38	drugs	drug	NOUN
admet-505	988	39	–	–	PUNCT
admet-505	988	40	consensus	consensus	NOUN
admet-505	988	41	recommendations	recommendation	NOUN
admet-505	988	42	for	for	ADP
admet-505	988	43	improving	improve	VERB
admet-505	988	44	data	datum	NOUN
admet-505	988	45	quality	quality	NOUN
admet-505	988	46	.	.	PUNCT
admet-505	989	1	admet	admet	PROPN
admet-505	989	2	&	&	CCONJ
admet-505	989	3	dmpk	dmpk	PROPN
admet-505	989	4	4	4	NUM
admet-505	989	5	(	(	PUNCT
admet-505	989	6	2016	2016	NUM
admet-505	989	7	)	)	PUNCT
admet-505	989	8	117	117	NUM
admet-505	989	9	-	-	SYM
admet-505	989	10	178	178	NUM
admet-505	989	11	.	.	PUNCT
admet-505	990	1	admet	admet	PROPN
admet-505	990	2	&	&	CCONJ
admet-505	990	3	dmpk	dmpk	PROPN
admet-505	990	4	6(2	6(2	NUM
admet-505	990	5	)	)	PUNCT
admet-505	990	6	(	(	PUNCT
admet-505	990	7	2018	2018	NUM
admet-505	990	8	)	)	PUNCT
admet-505	990	9	105	105	NUM
admet-505	990	10	-	-	SYM
admet-505	990	11	139	139	NUM
admet-505	990	12	cocrystal	cocrystal	ADJ
admet-505	990	13	solubility	solubility	NOUN
admet-505	990	14	-	-	PUNCT
admet-505	990	15	ph	ph	VERB
admet-505	990	16	,	,	PUNCT
admet-505	990	17	drug	drug	NOUN
admet-505	990	18	solubilization	solubilization	NOUN
admet-505	990	19	capacity	capacity	NOUN
admet-505	990	20	of	of	ADP
admet-505	990	21	sds	sds	PROPN
admet-505	990	22	,	,	PUNCT
admet-505	990	23	mass	mass	ADJ
admet-505	990	24	action	action	NOUN
admet-505	990	25	model	model	NOUN
admet-505	990	26	doi	doi	PROPN
admet-505	990	27	:	:	PUNCT
admet-505	990	28	10.5599	10.5599	NUM
admet-505	990	29	/	/	SYM
admet-505	990	30	admet.505	admet.505	PROPN
admet-505	990	31	137	137	NUM
admet-505	990	32	[	[	X
admet-505	990	33	57	57	NUM
admet-505	990	34	]	]	X
admet-505	990	35	n.	n.	PROPN
admet-505	990	36	sun	sun	PROPN
admet-505	990	37	,	,	PUNCT
admet-505	990	38	a.	a.	NOUN
admet-505	990	39	avdeef	avdeef	PROPN
admet-505	990	40	.	.	PUNCT
admet-505	991	1	biorelevant	biorelevant	PROPN
admet-505	991	2	pka	pka	PROPN
admet-505	991	3	(	(	PUNCT
admet-505	991	4	37	37	NUM
admet-505	991	5	o	o	NOUN
admet-505	991	6	c	c	NOUN
admet-505	991	7	)	)	PUNCT
admet-505	991	8	predicted	predict	VERB
admet-505	991	9	from	from	ADP
admet-505	991	10	the	the	DET
admet-505	991	11	2d	2d	NUM
admet-505	991	12	structure	structure	NOUN
admet-505	991	13	of	of	ADP
admet-505	991	14	the	the	DET
admet-505	991	15	molecule	molecule	NOUN
admet-505	991	16	and	and	CCONJ
admet-505	991	17	its	its	PRON
admet-505	991	18	pka	pka	NOUN
admet-505	991	19	at	at	ADP
admet-505	991	20	25	25	NUM
admet-505	991	21	°	°	NOUN
admet-505	991	22	c	c	NOUN
admet-505	991	23	.	.	PUNCT
admet-505	992	1	j.	j.	PROPN
admet-505	992	2	pharm	pharm	PROPN
admet-505	992	3	.	.	PUNCT
admet-505	992	4	biomed	biome	VERB
admet-505	992	5	.	.	PUNCT
admet-505	993	1	anal	anal	ADJ
admet-505	993	2	.	.	PUNCT
admet-505	994	1	56	56	NUM
admet-505	994	2	(	(	PUNCT
admet-505	994	3	2011	2011	NUM
admet-505	994	4	)	)	PUNCT
admet-505	994	5	173	173	NUM
admet-505	994	6	-	-	SYM
admet-505	994	7	182	182	NUM
admet-505	994	8	.	.	PUNCT
admet-505	995	1	[	[	X
admet-505	995	2	58	58	NUM
admet-505	995	3	]	]	X
admet-505	995	4	m.h	m.h	PROPN
admet-505	995	5	.	.	PROPN
admet-505	995	6	abraham	abraham	PROPN
admet-505	995	7	,	,	PUNCT
admet-505	995	8	h.s	h.s	PROPN
admet-505	995	9	.	.	PROPN
admet-505	995	10	chadha	chadha	PROPN
admet-505	995	11	,	,	PUNCT
admet-505	995	12	j.p	j.p	PROPN
admet-505	995	13	.	.	PROPN
admet-505	995	14	dixon	dixon	PROPN
admet-505	995	15	,	,	PUNCT
admet-505	995	16	c.	c.	PROPN
admet-505	995	17	ràfols	ràfols	PROPN
admet-505	995	18	,	,	PUNCT
admet-505	995	19	c.	c.	PROPN
admet-505	995	20	treiner	treiner	NOUN
admet-505	995	21	.	.	PUNCT
admet-505	996	1	hydrogen	hydrogen	NOUN
admet-505	996	2	bonding	bonding	NOUN
admet-505	996	3	.	.	PUNCT
admet-505	997	1	part	part	NOUN
admet-505	997	2	40	40	NUM
admet-505	997	3	.	.	PUNCT
admet-505	998	1	factors	factor	NOUN
admet-505	998	2	that	that	PRON
admet-505	998	3	influence	influence	VERB
admet-505	998	4	the	the	DET
admet-505	998	5	distribution	distribution	NOUN
admet-505	998	6	of	of	ADP
admet-505	998	7	solutes	solute	NOUN
admet-505	998	8	between	between	ADP
admet-505	998	9	water	water	NOUN
admet-505	998	10	and	and	CCONJ
admet-505	998	11	sodium	sodium	NOUN
admet-505	998	12	dodecyl	dodecyl	PROPN
admet-505	998	13	sulfate	sulfate	NOUN
admet-505	998	14	micelles	micelle	NOUN
admet-505	998	15	.	.	PUNCT
admet-505	999	1	j	j	PROPN
admet-505	999	2	.	.	PUNCT
admet-505	999	3	chem	chem	PROPN
admet-505	999	4	.	.	PUNCT
admet-505	1000	1	soc	soc	PROPN
admet-505	1000	2	.	.	PUNCT
admet-505	1001	1	perkin	perkin	PROPN
admet-505	1001	2	trans	trans	PROPN
admet-505	1001	3	.	.	PROPN
admet-505	1001	4	2	2	NUM
admet-505	1001	5	(	(	PUNCT
admet-505	1001	6	1995	1995	NUM
admet-505	1001	7	)	)	PUNCT
admet-505	1001	8	887	887	NUM
admet-505	1001	9	-	-	SYM
admet-505	1001	10	894	894	NUM
admet-505	1001	11	.	.	PUNCT
admet-505	1002	1	[	[	X
admet-505	1002	2	59	59	NUM
admet-505	1002	3	]	]	X
admet-505	1002	4	m.h	m.h	PROPN
admet-505	1002	5	.	.	PROPN
admet-505	1002	6	abraham	abraham	PROPN
admet-505	1002	7	.	.	PUNCT
admet-505	1003	1	scales	scale	NOUN
admet-505	1003	2	of	of	ADP
admet-505	1003	3	hydrogen	hydrogen	NOUN
admet-505	1003	4	bonding	bond	VERB
admet-505	1003	5	their	their	PRON
admet-505	1003	6	construction	construction	NOUN
admet-505	1003	7	and	and	CCONJ
admet-505	1003	8	application	application	NOUN
admet-505	1003	9	to	to	ADP
admet-505	1003	10	physicochemical	physicochemical	ADJ
admet-505	1003	11	and	and	CCONJ
admet-505	1003	12	biochemical	biochemical	ADJ
admet-505	1003	13	processes	process	NOUN
admet-505	1003	14	.	.	PUNCT
admet-505	1004	1	chem	chem	NOUN
admet-505	1004	2	.	.	PUNCT
admet-505	1005	1	soc	soc	PROPN
admet-505	1005	2	.	.	PUNCT
admet-505	1006	1	revs	revs	VERB
admet-505	1006	2	.	.	PUNCT
admet-505	1007	1	22	22	NUM
admet-505	1007	2	(	(	PUNCT
admet-505	1007	3	1993	1993	NUM
admet-505	1007	4	)	)	PUNCT
admet-505	1007	5	73	73	NUM
admet-505	1007	6	-	-	SYM
admet-505	1007	7	83	83	NUM
admet-505	1007	8	.	.	PUNCT
admet-505	1008	1	[	[	X
admet-505	1008	2	60	60	NUM
admet-505	1008	3	]	]	X
admet-505	1008	4	y.	y.	PROPN
admet-505	1008	5	ran	run	VERB
admet-505	1008	6	,	,	PUNCT
admet-505	1008	7	a.	a.	NOUN
admet-505	1008	8	jain	jain	PROPN
admet-505	1008	9	,	,	PUNCT
admet-505	1008	10	s.h	s.h	PROPN
admet-505	1008	11	.	.	NOUN
admet-505	1008	12	yalkowsky	yalkowsky	ADJ
admet-505	1008	13	.	.	PUNCT
admet-505	1009	1	solubilization	solubilization	NOUN
admet-505	1009	2	and	and	CCONJ
admet-505	1009	3	preformulation	preformulation	NOUN
admet-505	1009	4	studies	study	NOUN
admet-505	1009	5	on	on	ADP
admet-505	1009	6	pg-300995	pg-300995	PROPN
admet-505	1009	7	(	(	PUNCT
admet-505	1009	8	an	an	DET
admet-505	1009	9	anti	anti	ADJ
admet-505	1009	10	-	-	ADJ
admet-505	1009	11	hiv	hiv	ADJ
admet-505	1009	12	drug	drug	NOUN
admet-505	1009	13	)	)	PUNCT
admet-505	1009	14	.	.	PUNCT
admet-505	1010	1	j.	j.	PROPN
admet-505	1010	2	pharm	pharm	PROPN
admet-505	1010	3	.	.	PUNCT
admet-505	1011	1	sci	sci	PROPN
admet-505	1011	2	.	.	PROPN
admet-505	1012	1	94	94	NUM
admet-505	1012	2	(	(	PUNCT
admet-505	1012	3	2005	2005	NUM
admet-505	1012	4	)	)	PUNCT
admet-505	1012	5	297	297	NUM
admet-505	1012	6	-	-	SYM
admet-505	1012	7	303	303	NUM
admet-505	1012	8	.	.	PUNCT
admet-505	1013	1	[	[	X
admet-505	1013	2	61	61	NUM
admet-505	1013	3	]	]	X
admet-505	1013	4	c.	c.	PROPN
admet-505	1013	5	stubbs	stubbs	PROPN
admet-505	1013	6	,	,	PUNCT
admet-505	1013	7	i.	i.	PROPN
admet-505	1013	8	kanfer	kanfer	PROPN
admet-505	1013	9	.	.	PUNCT
admet-505	1014	1	a	a	DET
admet-505	1014	2	stability	stability	NOUN
admet-505	1014	3	indicating	indicate	VERB
admet-505	1014	4	high	high	ADJ
admet-505	1014	5	-	-	PUNCT
admet-505	1014	6	performance	performance	NOUN
admet-505	1014	7	liquid	liquid	ADJ
admet-505	1014	8	chromatographic	chromatographic	ADJ
admet-505	1014	9	assay	assay	NOUN
admet-505	1014	10	of	of	ADP
admet-505	1014	11	erythromycin	erythromycin	NOUN
admet-505	1014	12	estolate	estolate	ADJ
admet-505	1014	13	in	in	ADP
admet-505	1014	14	pharmaceutical	pharmaceutical	ADJ
admet-505	1014	15	dosage	dosage	NOUN
admet-505	1014	16	forms	form	NOUN
admet-505	1014	17	.	.	PUNCT
admet-505	1015	1	int	int	NOUN
admet-505	1015	2	.	.	PUNCT
admet-505	1016	1	j.	j.	PROPN
admet-505	1016	2	pharm	pharm	PROPN
admet-505	1016	3	.	.	PUNCT
admet-505	1017	1	63	63	NUM
admet-505	1017	2	(	(	PUNCT
admet-505	1017	3	1990	1990	NUM
admet-505	1017	4	)	)	PUNCT
admet-505	1017	5	113	113	NUM
admet-505	1017	6	-	-	SYM
admet-505	1017	7	119	119	NUM
admet-505	1017	8	.	.	PUNCT
admet-505	1018	1	[	[	X
admet-505	1018	2	62	62	NUM
admet-505	1018	3	]	]	X
admet-505	1018	4	d.j	d.j	PROPN
admet-505	1018	5	.	.	PROPN
admet-505	1018	6	good	good	PROPN
admet-505	1018	7	,	,	PUNCT
admet-505	1018	8	n.	n.	PROPN
admet-505	1018	9	rodríguez	rodríguez	PROPN
admet-505	1018	10	-	-	PUNCT
admet-505	1018	11	hornedo	hornedo	NOUN
admet-505	1018	12	.	.	PUNCT
admet-505	1019	1	solubility	solubility	NOUN
admet-505	1019	2	advantage	advantage	NOUN
admet-505	1019	3	of	of	ADP
admet-505	1019	4	pharmaceutical	pharmaceutical	ADJ
admet-505	1019	5	cocrystals	cocrystal	NOUN
admet-505	1019	6	.	.	PUNCT
admet-505	1020	1	cryst	cryst	PROPN
admet-505	1020	2	.	.	PUNCT
admet-505	1021	1	growth	growth	PROPN
admet-505	1021	2	des	des	PROPN
admet-505	1021	3	.	.	PROPN
admet-505	1021	4	9	9	NUM
admet-505	1021	5	(	(	PUNCT
admet-505	1021	6	2009	2009	NUM
admet-505	1021	7	)	)	PUNCT
admet-505	1021	8	2252	2252	NUM
admet-505	1021	9	-	-	SYM
admet-505	1021	10	2264	2264	NUM
admet-505	1021	11	.	.	PUNCT
admet-505	1022	1	[	[	X
admet-505	1022	2	63	63	NUM
admet-505	1022	3	]	]	SYM
admet-505	1022	4	n.c	n.c	PROPN
admet-505	1022	5	.	.	PROPN
admet-505	1022	6	huang	huang	PROPN
admet-505	1022	7	.	.	PUNCT
admet-505	1022	8	engineering	engineering	PROPN
admet-505	1022	9	cocrystal	cocrystal	PROPN
admet-505	1022	10	solubility	solubility	NOUN
admet-505	1022	11	and	and	CCONJ
admet-505	1022	12	stability	stability	NOUN
admet-505	1022	13	via	via	ADP
admet-505	1022	14	ionization	ionization	NOUN
admet-505	1022	15	and	and	CCONJ
admet-505	1022	16	micellar	micellar	ADJ
admet-505	1022	17	solubilization	solubilization	NOUN
admet-505	1022	18	.	.	PUNCT
admet-505	1023	1	phd	phd	NOUN
admet-505	1023	2	thesis	thesis	PROPN
admet-505	1023	3	,	,	PUNCT
admet-505	1023	4	university	university	NOUN
admet-505	1023	5	of	of	ADP
admet-505	1023	6	michigan	michigan	PROPN
admet-505	1023	7	,	,	PUNCT
admet-505	1023	8	2011	2011	NUM
admet-505	1023	9	.	.	PUNCT
admet-505	1024	1	[	[	X
admet-505	1024	2	64	64	NUM
admet-505	1024	3	]	]	PUNCT
admet-505	1024	4	a.	a.	NOUN
admet-505	1024	5	alhalaweh	alhalaweh	PROPN
admet-505	1024	6	,	,	PUNCT
admet-505	1024	7	l.	l.	PROPN
admet-505	1024	8	roy	roy	PROPN
admet-505	1024	9	,	,	PUNCT
admet-505	1024	10	n.	n.	PROPN
admet-505	1024	11	rodríguez	rodríguez	PROPN
admet-505	1024	12	-	-	PUNCT
admet-505	1024	13	hornedo	hornedo	PROPN
admet-505	1024	14	,	,	PUNCT
admet-505	1024	15	s.p	s.p	PROPN
admet-505	1024	16	.	.	PROPN
admet-505	1024	17	velaga	velaga	PROPN
admet-505	1024	18	.	.	PUNCT
admet-505	1025	1	ph	ph	ADJ
admet-505	1025	2	-	-	ADJ
admet-505	1025	3	dependent	dependent	ADJ
admet-505	1025	4	solubility	solubility	NOUN
admet-505	1025	5	of	of	ADP
admet-505	1025	6	indomethacinsaccharin	indomethacinsaccharin	NOUN
admet-505	1025	7	and	and	CCONJ
admet-505	1025	8	carbamazepine	carbamazepine	NOUN
admet-505	1025	9	-	-	PUNCT
admet-505	1025	10	saccharin	saccharin	NOUN
admet-505	1025	11	cocrystals	cocrystal	NOUN
admet-505	1025	12	in	in	ADP
admet-505	1025	13	aqueous	aqueous	ADJ
admet-505	1025	14	media	medium	NOUN
admet-505	1025	15	.	.	PUNCT
admet-505	1026	1	mol	mol	PROPN
admet-505	1026	2	.	.	PUNCT
admet-505	1026	3	pharmaceutics	pharmaceutic	NOUN
admet-505	1026	4	.	.	PUNCT
admet-505	1027	1	9	9	NUM
admet-505	1027	2	(	(	PUNCT
admet-505	1027	3	2012	2012	NUM
admet-505	1027	4	)	)	PUNCT
admet-505	1027	5	2605	2605	NUM
admet-505	1027	6	-	-	SYM
admet-505	1027	7	2612	2612	NUM
admet-505	1027	8	.	.	PUNCT
admet-505	1028	1	[	[	X
admet-505	1028	2	65	65	NUM
admet-505	1028	3	]	]	X
admet-505	1028	4	n.	n.	PROPN
admet-505	1028	5	schultheiss	schultheiss	PROPN
admet-505	1028	6	,	,	PUNCT
admet-505	1028	7	s.	s.	PROPN
admet-505	1028	8	bethune	bethune	PROPN
admet-505	1028	9	,	,	PUNCT
admet-505	1028	10	j.-o	j.-o	NOUN
admet-505	1028	11	.	.	PUNCT
admet-505	1029	1	henck	henck	PROPN
admet-505	1029	2	.	.	PUNCT
admet-505	1030	1	nutraceutical	nutraceutical	ADJ
admet-505	1030	2	cocrystals	cocrystal	NOUN
admet-505	1030	3	:	:	PUNCT
admet-505	1030	4	utilizing	utilize	VERB
admet-505	1030	5	pterostilbene	pterostilbene	NOUN
admet-505	1030	6	as	as	ADP
admet-505	1030	7	a	a	DET
admet-505	1030	8	cocrystal	cocrystal	ADJ
admet-505	1030	9	former	former	ADJ
admet-505	1030	10	.	.	PUNCT
admet-505	1030	11	crystengcomm	crystengcomm	NOUN
admet-505	1030	12	.	.	PUNCT
admet-505	1031	1	12	12	NUM
admet-505	1031	2	(	(	PUNCT
admet-505	1031	3	2010	2010	NUM
admet-505	1031	4	)	)	PUNCT
admet-505	1031	5	2436–2442	2436–2442	NUM
admet-505	1031	6	.	.	PUNCT
admet-505	1032	1	alex	alex	PROPN
admet-505	1032	2	avdeef	avdeef	PROPN
admet-505	1032	3	admet	admet	PROPN
admet-505	1032	4	&	&	CCONJ
admet-505	1032	5	dmpk	dmpk	PROPN
admet-505	1032	6	6(2	6(2	NUM
admet-505	1032	7	)	)	PUNCT
admet-505	1032	8	(	(	PUNCT
admet-505	1032	9	2018	2018	NUM
admet-505	1032	10	)	)	PUNCT
admet-505	1032	11	105	105	NUM
admet-505	1032	12	-	-	SYM
admet-505	1032	13	139	139	NUM
admet-505	1032	14	138	138	NUM
admet-505	1032	15	appendix	appendix	NOUN
admet-505	1032	16	.	.	PUNCT
admet-505	1033	1	function	function	NOUN
admet-505	1033	2	minimized	minimize	VERB
admet-505	1033	3	in	in	ADP
admet-505	1033	4	refinement	refinement	NOUN
admet-505	1033	5	of	of	ADP
admet-505	1033	6	cocrystal	cocrystal	ADJ
admet-505	1033	7	solubility	solubility	NOUN
admet-505	1033	8	products	product	NOUN
admet-505	1033	9	and	and	CCONJ
admet-505	1033	10	drug	drug	NOUN
admet-505	1033	11	-	-	PUNCT
admet-505	1033	12	surfactant	surfactant	NOUN
admet-505	1033	13	binding	bind	VERB
admet-505	1033	14	constants	constant	NOUN
admet-505	1033	15	function	function	NOUN
admet-505	1033	16	minimized	minimize	VERB
admet-505	1033	17	in	in	ADP
admet-505	1033	18	the	the	DET
admet-505	1033	19	weighted	weighted	ADJ
admet-505	1033	20	nonlinear	nonlinear	ADJ
admet-505	1033	21	regression	regression	NOUN
admet-505	1033	22	analysis	analysis	NOUN
admet-505	1033	23	the	the	DET
admet-505	1033	24	refined	refined	ADJ
admet-505	1033	25	equilibrium	equilibrium	NOUN
admet-505	1033	26	constants	constant	NOUN
admet-505	1033	27	(	(	PUNCT
admet-505	1033	28	drug	drug	NOUN
admet-505	1033	29	-	-	PUNCT
admet-505	1033	30	micelle	micelle	NOUN
admet-505	1033	31	binding	bind	VERB
admet-505	1033	32	constant	constant	ADJ
admet-505	1033	33	,	,	PUNCT
admet-505	1033	34	kn	kn	PROPN
admet-505	1033	35	,	,	PUNCT
admet-505	1033	36	cocrystal	cocrystal	PROPN
admet-505	1033	37	ksp	ksp	PROPN
admet-505	1033	38	and	and	CCONJ
admet-505	1033	39	api	api	PROPN
admet-505	1033	40	intrinsic	intrinsic	PROPN
admet-505	1033	41	solubility	solubility	PROPN
admet-505	1033	42	,	,	PUNCT
admet-505	1033	43	s0	s0	PROPN
admet-505	1033	44	)	)	PUNCT
admet-505	1033	45	,	,	PUNCT
admet-505	1033	46	along	along	ADP
admet-505	1033	47	with	with	ADP
admet-505	1033	48	other	other	ADJ
admet-505	1033	49	unrefined	unrefined	ADJ
admet-505	1033	50	constants	constant	NOUN
admet-505	1033	51	(	(	PUNCT
admet-505	1033	52	e.g.	e.g.	ADV
admet-505	1033	53	,	,	PUNCT
admet-505	1033	54	api	api	NOUN
admet-505	1033	55	and	and	CCONJ
admet-505	1033	56	coformer	coformer	NOUN
admet-505	1033	57	pka	pka	PROPN
admet-505	1033	58	values	value	NOUN
admet-505	1033	59	)	)	PUNCT
admet-505	1033	60	,	,	PUNCT
admet-505	1033	61	and	and	CCONJ
admet-505	1033	62	the	the	DET
admet-505	1033	63	given	give	VERB
admet-505	1033	64	independent	independent	ADJ
admet-505	1033	65	variables	variable	NOUN
admet-505	1033	66	(	(	PUNCT
admet-505	1033	67	sample	sample	NOUN
admet-505	1033	68	weights	weight	NOUN
admet-505	1033	69	,	,	PUNCT
admet-505	1033	70	reagent	reagent	ADJ
admet-505	1033	71	volumes	volume	NOUN
admet-505	1033	72	,	,	PUNCT
admet-505	1033	73	surfactant	surfactant	ADJ
admet-505	1033	74	concentration	concentration	NOUN
admet-505	1033	75	,	,	PUNCT
admet-505	1033	76	etc	etc	X
admet-505	1033	77	.	.	X
admet-505	1033	78	)	)	PUNCT
admet-505	1033	79	,	,	PUNCT
admet-505	1033	80	are	be	AUX
admet-505	1033	81	used	use	VERB
admet-505	1033	82	to	to	PART
admet-505	1033	83	calculate	calculate	VERB
admet-505	1033	84	the	the	DET
admet-505	1033	85	dependent	dependent	ADJ
admet-505	1033	86	variables	variable	NOUN
admet-505	1033	87	:	:	PUNCT
admet-505	1033	88	the	the	DET
admet-505	1033	89	eutectic	eutectic	PROPN
admet-505	1033	90	/	/	SYM
admet-505	1033	91	eutectoid	eutectoid	ADJ
admet-505	1033	92	total	total	ADJ
admet-505	1033	93	concentrations	concentration	NOUN
admet-505	1033	94	of	of	ADP
admet-505	1033	95	the	the	DET
admet-505	1033	96	api	api	NOUN
admet-505	1033	97	(	(	PUNCT
admet-505	1033	98	general	general	ADJ
admet-505	1033	99	symbol	symbol	NOUN
admet-505	1033	100	xtot	xtot	PROPN
admet-505	1033	101	)	)	PUNCT
admet-505	1033	102	and	and	CCONJ
admet-505	1033	103	the	the	DET
admet-505	1033	104	coformer	coformer	NOUN
admet-505	1033	105	(	(	PUNCT
admet-505	1033	106	general	general	ADJ
admet-505	1033	107	symbol	symbol	NOUN
admet-505	1033	108	ytot	ytot	NOUN
admet-505	1033	109	)	)	PUNCT
admet-505	1033	110	.	.	PUNCT
admet-505	1034	1	the	the	DET
admet-505	1034	2	calculated	calculated	ADJ
admet-505	1034	3	total	total	ADJ
admet-505	1034	4	concentrations	concentration	NOUN
admet-505	1034	5	are	be	AUX
admet-505	1034	6	then	then	ADV
admet-505	1034	7	compared	compare	VERB
admet-505	1034	8	to	to	ADP
admet-505	1034	9	the	the	DET
admet-505	1034	10	corresponding	corresponding	ADJ
admet-505	1034	11	observed	observe	VERB
admet-505	1034	12	values	value	NOUN
admet-505	1034	13	at	at	ADP
admet-505	1034	14	each	each	DET
admet-505	1034	15	measured	measure	VERB
admet-505	1034	16	ph	ph	VERB
admet-505	1034	17	.	.	PUNCT
admet-505	1035	1	the	the	DET
admet-505	1035	2	refined	refined	ADJ
admet-505	1035	3	‘	'	PUNCT
admet-505	1035	4	best	good	ADJ
admet-505	1035	5	’	'	PUNCT
admet-505	1035	6	values	value	NOUN
admet-505	1035	7	are	be	AUX
admet-505	1035	8	those	those	PRON
admet-505	1035	9	which	which	PRON
admet-505	1035	10	produce	produce	VERB
admet-505	1035	11	a	a	DET
admet-505	1035	12	minimum	minimum	NOUN
admet-505	1035	13	in	in	ADP
admet-505	1035	14	the	the	DET
admet-505	1035	15	sums	sum	NOUN
admet-505	1035	16	of	of	ADP
admet-505	1035	17	the	the	DET
admet-505	1035	18	weighted	weight	VERB
admet-505	1035	19	squares	square	NOUN
admet-505	1035	20	of	of	ADP
admet-505	1035	21	two	two	NUM
admet-505	1035	22	sets	set	NOUN
admet-505	1035	23	of	of	ADP
admet-505	1035	24	residuals	residual	NOUN
admet-505	1035	25	,	,	PUNCT
admet-505	1035	26	2	2	NUM
admet-505	1035	27	,	,	PUNCT
admet-505	1035	28	,	,	PUNCT
admet-505	1035	29	,	,	PUNCT
admet-505	1035	30	2	2	NUM
admet-505	1035	31	,	,	PUNCT
admet-505	1035	32	,	,	PUNCT
admet-505	1035	33	,	,	PUNCT
admet-505	1035	34	0	0	NUM
admet-505	1035	35	)	)	PUNCT
admet-505	1035	36	(	(	PUNCT
admet-505	1035	37	log	log	NOUN
admet-505	1035	38	loglog	loglog	NOUN
admet-505	1035	39	)	)	PUNCT
admet-505	1035	40	(	(	PUNCT
admet-505	1035	41	log	log	PROPN
admet-505	1035	42	loglog	loglog	PROPN
admet-505	1035	43			PROPN
admet-505	1036	1			PROPN
admet-505	1036	2			PROPN
admet-505	1036	3			NOUN
admet-505	1037	1			PROPN
admet-505	1037	2			PROPN
admet-505	1037	3			PROPN
admet-505	1037	4			PROPN
admet-505	1037	5			PROPN
admet-505	1037	6			PROPN
admet-505	1037	7			PROPN
admet-505	1037	8			PROPN
admet-505	1037	9			PROPN
admet-505	1037	10			NOUN
admet-505	1037	11			PROPN
admet-505	1037	12			PROPN
admet-505	1037	13			PROPN
admet-505	1038	1			PROPN
admet-505	1038	2			NOUN
admet-505	1038	3			PROPN
admet-505	1038	4			PROPN
admet-505	1038	5	cof	cof	PROPN
admet-505	1038	6	o	o	PROPN
admet-505	1039	1	n	n	CCONJ
admet-505	1040	1	i	i	PRON
admet-505	1040	2	obs	obs	PROPN
admet-505	1040	3	itoti	itoti	PROPN
admet-505	1040	4	calc	calc	PROPN
admet-505	1040	5	itot	itot	PROPN
admet-505	1040	6	obs	obs	PROPN
admet-505	1040	7	itot	itot	ADJ
admet-505	1040	8	n	n	PROPN
admet-505	1041	1	i	i	PRON
admet-505	1041	2	obs	obs	PROPN
admet-505	1041	3	itoti	itoti	PROPN
admet-505	1041	4	calc	calc	PROPN
admet-505	1041	5	itot	itot	PROPN
admet-505	1041	6	obs	obs	PROPN
admet-505	1041	7	itot	itot	ADJ
admet-505	1041	8	w	w	PROPN
admet-505	1041	9	y	y	PROPN
admet-505	1041	10	yy	yy	INTJ
admet-505	1041	11	x	x	PUNCT
admet-505	1042	1	xx	xx	NUM
admet-505	1042	2	r	r	NOUN
admet-505	1042	3			PROPN
admet-505	1042	4	(	(	PUNCT
admet-505	1042	5	a.1	a.1	NOUN
admet-505	1042	6	)	)	PUNCT
admet-505	1042	7	n0	n0	NOUN
admet-505	1042	8	and	and	CCONJ
admet-505	1042	9	n0	n0	PROPN
admet-505	1042	10	cof	cof	PROPN
admet-505	1042	11	are	be	AUX
admet-505	1042	12	the	the	DET
admet-505	1042	13	number	number	NOUN
admet-505	1042	14	of	of	ADP
admet-505	1042	15	api	api	NOUN
admet-505	1042	16	and	and	CCONJ
admet-505	1042	17	coformer	coformer	NOUN
admet-505	1042	18	measurements	measurement	NOUN
admet-505	1042	19	as	as	ADP
admet-505	1042	20	a	a	DET
admet-505	1042	21	function	function	NOUN
admet-505	1042	22	of	of	ADP
admet-505	1042	23	ph	ph	NOUN
admet-505	1042	24	,	,	PUNCT
admet-505	1042	25	respectively	respectively	ADV
admet-505	1042	26	;	;	PUNCT
admet-505	1042	27	σ	σ	X
admet-505	1042	28	is	be	AUX
admet-505	1042	29	the	the	DET
admet-505	1042	30	estimated	estimate	VERB
admet-505	1042	31	standard	standard	ADJ
admet-505	1042	32	deviation	deviation	NOUN
admet-505	1042	33	in	in	ADP
admet-505	1042	34	the	the	DET
admet-505	1042	35	measured	measure	VERB
admet-505	1042	36	log	log	NOUN
admet-505	1042	37	value	value	NOUN
admet-505	1042	38	.	.	PUNCT
admet-505	1043	1	(	(	PUNCT
admet-505	1043	2	when	when	SCONJ
admet-505	1043	3	σ	σ	PROPN
admet-505	1043	4	values	value	NOUN
admet-505	1043	5	were	be	AUX
admet-505	1043	6	not	not	PART
admet-505	1043	7	available	available	ADJ
admet-505	1043	8	,	,	PUNCT
admet-505	1043	9	0.1	0.1	NUM
admet-505	1043	10	log	log	NOUN
admet-505	1043	11	unit	unit	NOUN
admet-505	1043	12	was	be	AUX
admet-505	1043	13	assumed	assume	VERB
admet-505	1043	14	.	.	PUNCT
admet-505	1043	15	)	)	PUNCT
admet-505	1044	1	xtot	xtot	PROPN
admet-505	1044	2	calc	calc	PROPN
admet-505	1044	3	and	and	CCONJ
admet-505	1044	4	ytot	ytot	PROPN
admet-505	1044	5	calc	calc	NOUN
admet-505	1044	6	are	be	AUX
admet-505	1044	7	functions	function	NOUN
admet-505	1044	8	of	of	ADP
admet-505	1044	9	the	the	DET
admet-505	1044	10	equilibrium	equilibrium	NOUN
admet-505	1044	11	constants	constant	NOUN
admet-505	1044	12	,	,	PUNCT
admet-505	1044	13	as	as	ADV
admet-505	1044	14	well	well	ADV
admet-505	1044	15	as	as	ADP
admet-505	1044	16	the	the	DET
admet-505	1044	17	independent	independent	ADJ
admet-505	1044	18	variables	variable	NOUN
admet-505	1044	19	.	.	PUNCT
admet-505	1045	1	overview	overview	NOUN
admet-505	1045	2	of	of	ADP
admet-505	1045	3	the	the	DET
admet-505	1045	4	refinement	refinement	NOUN
admet-505	1045	5	procedure	procedure	NOUN
admet-505	1045	6	two	two	NUM
admet-505	1045	7	separate	separate	ADJ
admet-505	1045	8	stages	stage	NOUN
admet-505	1045	9	of	of	ADP
admet-505	1045	10	refinement	refinement	NOUN
admet-505	1045	11	comprise	comprise	VERB
admet-505	1045	12	the	the	DET
admet-505	1045	13	overall	overall	ADJ
admet-505	1045	14	procedure	procedure	NOUN
admet-505	1045	15	.	.	PUNCT
admet-505	1046	1	(	(	PUNCT
admet-505	1046	2	i	i	NOUN
admet-505	1046	3	)	)	PUNCT
admet-505	1046	4	at	at	ADP
admet-505	1046	5	the	the	DET
admet-505	1046	6	‘	'	PUNCT
admet-505	1046	7	local	local	ADJ
admet-505	1046	8	’	'	PUNCT
admet-505	1046	9	refinement	refinement	NOUN
admet-505	1046	10	stage	stage	NOUN
admet-505	1046	11	(	(	PUNCT
admet-505	1046	12	pp	pp	ADJ
admet-505	1046	13	.	.	PUNCT
admet-505	1047	1	152	152	NUM
admet-505	1047	2	-	-	SYM
admet-505	1047	3	154	154	NUM
admet-505	1047	4	[	[	X
admet-505	1047	5	27	27	NUM
admet-505	1047	6	]	]	NUM
admet-505	1047	7	)	)	PUNCT
admet-505	1047	8	,	,	PUNCT
admet-505	1047	9	the	the	DET
admet-505	1047	10	mass	mass	NOUN
admet-505	1047	11	balance	balance	NOUN
admet-505	1047	12	equations	equation	NOUN
admet-505	1047	13	(	(	PUNCT
admet-505	1047	14	e.g.	e.g.	ADV
admet-505	1047	15	,	,	PUNCT
admet-505	1047	16	eqs	eqs	X
admet-505	1047	17	.	.	PROPN
admet-505	1047	18	(	(	PUNCT
admet-505	1047	19	8)-(10	8)-(10	NUM
admet-505	1047	20	)	)	PUNCT
admet-505	1047	21	)	)	PUNCT
admet-505	1047	22	,	,	PUNCT
admet-505	1047	23	which	which	PRON
admet-505	1047	24	are	be	AUX
admet-505	1047	25	nonlinear	nonlinear	ADJ
admet-505	1047	26	polynomials	polynomial	NOUN
admet-505	1047	27	in	in	ADP
admet-505	1047	28	terms	term	NOUN
admet-505	1047	29	of	of	ADP
admet-505	1047	30	the	the	DET
admet-505	1047	31	reactant	reactant	NOUN
admet-505	1047	32	concentrations	concentration	NOUN
admet-505	1047	33	and	and	CCONJ
admet-505	1047	34	equilibrium	equilibrium	NOUN
admet-505	1047	35	constants	constant	NOUN
admet-505	1047	36	,	,	PUNCT
admet-505	1047	37	are	be	AUX
admet-505	1047	38	simultaneously	simultaneously	ADV
admet-505	1047	39	solved	solve	VERB
admet-505	1047	40	by	by	ADP
admet-505	1047	41	the	the	DET
admet-505	1047	42	jacobian	jacobian	ADJ
admet-505	1047	43	method	method	NOUN
admet-505	1047	44	for	for	ADP
admet-505	1047	45	reactant	reactant	NOUN
admet-505	1047	46	concentrations	concentration	NOUN
admet-505	1047	47	at	at	ADP
admet-505	1047	48	each	each	DET
admet-505	1047	49	measured	measure	VERB
admet-505	1047	50	solubility	solubility	NOUN
admet-505	1047	51	point	point	NOUN
admet-505	1047	52	,	,	PUNCT
admet-505	1047	53	for	for	ADP
admet-505	1047	54	a	a	DET
admet-505	1047	55	given	give	VERB
admet-505	1047	56	set	set	NOUN
admet-505	1047	57	of	of	ADP
admet-505	1047	58	equilibrium	equilibrium	NOUN
admet-505	1047	59	constants	constant	NOUN
admet-505	1047	60	.	.	PUNCT
admet-505	1048	1	if	if	SCONJ
admet-505	1048	2	there	there	PRON
admet-505	1048	3	are	be	VERB
admet-505	1048	4	three	three	NUM
admet-505	1048	5	independent	independent	ADJ
admet-505	1048	6	reactants	reactant	NOUN
admet-505	1048	7	,	,	PUNCT
admet-505	1048	8	then	then	ADV
admet-505	1048	9	there	there	PRON
admet-505	1048	10	will	will	AUX
admet-505	1048	11	be	be	AUX
admet-505	1048	12	three	three	NUM
admet-505	1048	13	mass	mass	NOUN
admet-505	1048	14	balance	balance	NOUN
admet-505	1048	15	equations	equation	NOUN
admet-505	1048	16	.	.	PUNCT
admet-505	1049	1	the	the	DET
admet-505	1049	2	local	local	ADJ
admet-505	1049	3	step	step	NOUN
admet-505	1049	4	involves	involve	VERB
admet-505	1049	5	the	the	DET
admet-505	1049	6	inversion	inversion	NOUN
admet-505	1049	7	of	of	ADP
admet-505	1049	8	a	a	DET
admet-505	1049	9	symmetric	symmetric	ADJ
admet-505	1049	10	jacobian	jacobian	ADJ
admet-505	1049	11	matrix	matrix	NOUN
admet-505	1049	12	(	(	PUNCT
admet-505	1049	13	whose	whose	DET
admet-505	1049	14	elements	element	NOUN
admet-505	1049	15	are	be	AUX
admet-505	1049	16	partial	partial	ADJ
admet-505	1049	17	derivatives	derivative	NOUN
admet-505	1049	18	of	of	ADP
admet-505	1049	19	total	total	ADJ
admet-505	1049	20	concentrations	concentration	NOUN
admet-505	1049	21	as	as	ADP
admet-505	1049	22	a	a	DET
admet-505	1049	23	function	function	NOUN
admet-505	1049	24	of	of	ADP
admet-505	1049	25	the	the	DET
admet-505	1049	26	logarithmic	logarithmic	ADJ
admet-505	1049	27	reactant	reactant	NOUN
admet-505	1049	28	concentrations	concentration	NOUN
admet-505	1049	29	)	)	PUNCT
admet-505	1049	30	at	at	ADP
admet-505	1049	31	each	each	DET
admet-505	1049	32	observed	observe	VERB
admet-505	1049	33	eutectic	eutectic	NOUN
admet-505	1049	34	/	/	SYM
admet-505	1049	35	eutectoid	eutectoid	NOUN
admet-505	1049	36	-	-	PUNCT
admet-505	1049	37	ph	ph	VERB
admet-505	1049	38	measurement	measurement	NOUN
admet-505	1049	39	.	.	PUNCT
admet-505	1050	1	if	if	SCONJ
admet-505	1050	2	solids	solid	NOUN
admet-505	1050	3	are	be	AUX
admet-505	1050	4	part	part	NOUN
admet-505	1050	5	of	of	ADP
admet-505	1050	6	the	the	DET
admet-505	1050	7	system	system	NOUN
admet-505	1050	8	,	,	PUNCT
admet-505	1050	9	then	then	ADV
admet-505	1050	10	the	the	DET
admet-505	1050	11	computation	computation	NOUN
admet-505	1050	12	of	of	ADP
admet-505	1050	13	the	the	DET
admet-505	1050	14	reactant	reactant	NOUN
admet-505	1050	15	concentrations	concentration	NOUN
admet-505	1050	16	becomes	become	VERB
admet-505	1050	17	quite	quite	ADV
admet-505	1050	18	complicated	complicated	ADJ
admet-505	1050	19	,	,	PUNCT
admet-505	1050	20	as	as	SCONJ
admet-505	1050	21	described	describe	VERB
admet-505	1050	22	in	in	ADP
admet-505	1050	23	detail	detail	NOUN
admet-505	1050	24	elsewhere	elsewhere	ADV
admet-505	1050	25	[	[	X
admet-505	1050	26	16	16	NUM
admet-505	1050	27	]	]	PUNCT
admet-505	1050	28	.	.	PUNCT
admet-505	1051	1	(	(	PUNCT
admet-505	1051	2	ii	ii	NOUN
admet-505	1051	3	)	)	PUNCT
admet-505	1051	4	at	at	ADP
admet-505	1051	5	the	the	DET
admet-505	1051	6	‘	'	PUNCT
admet-505	1051	7	global	global	ADJ
admet-505	1051	8	’	'	PUNCT
admet-505	1051	9	stage	stage	NOUN
admet-505	1051	10	of	of	ADP
admet-505	1051	11	refinement	refinement	NOUN
admet-505	1051	12	(	(	PUNCT
admet-505	1051	13	pp	pp	ADJ
admet-505	1051	14	.	.	PUNCT
admet-505	1052	1	154	154	NUM
admet-505	1052	2	-	-	SYM
admet-505	1052	3	155	155	NUM
admet-505	1053	1	[	[	X
admet-505	1053	2	27	27	NUM
admet-505	1053	3	]	]	NUM
admet-505	1053	4	)	)	PUNCT
admet-505	1053	5	,	,	PUNCT
admet-505	1053	6	the	the	DET
admet-505	1053	7	gauss	gauss	PROPN
admet-505	1053	8	-	-	PUNCT
admet-505	1053	9	newton	newton	PROPN
admet-505	1053	10	method	method	NOUN
admet-505	1053	11	is	be	AUX
admet-505	1053	12	used	use	VERB
admet-505	1053	13	to	to	PART
admet-505	1053	14	approximate	approximate	VERB
admet-505	1053	15	the	the	DET
admet-505	1053	16	log	log	NOUN
admet-505	1053	17	ctot	ctot	NOUN
admet-505	1053	18	values	value	NOUN
admet-505	1053	19	(	(	PUNCT
admet-505	1053	20	based	base	VERB
admet-505	1053	21	on	on	ADP
admet-505	1053	22	the	the	DET
admet-505	1053	23	mass	mass	NOUN
admet-505	1053	24	balance	balance	NOUN
admet-505	1053	25	equations	equation	NOUN
admet-505	1053	26	)	)	PUNCT
admet-505	1053	27	by	by	ADP
admet-505	1053	28	‘	'	PUNCT
admet-505	1053	29	normal	normal	ADJ
admet-505	1053	30	equations	equation	NOUN
admet-505	1053	31	’	'	PUNCT
admet-505	1053	32	(	(	PUNCT
admet-505	1053	33	one	one	NUM
admet-505	1053	34	for	for	ADP
admet-505	1053	35	each	each	DET
admet-505	1053	36	sampled	sample	VERB
admet-505	1053	37	log	log	NOUN
admet-505	1053	38	ctot	ctot	NOUN
admet-505	1053	39	-	-	PUNCT
admet-505	1053	40	ph	ph	VERB
admet-505	1053	41	)	)	PUNCT
admet-505	1053	42	,	,	PUNCT
admet-505	1053	43	linearized	linearize	VERB
admet-505	1053	44	by	by	ADP
admet-505	1053	45	taylor	taylor	PROPN
admet-505	1053	46	series	series	PROPN
admet-505	1053	47	expansion	expansion	NOUN
admet-505	1053	48	.	.	PUNCT
admet-505	1054	1	the	the	DET
admet-505	1054	2	least	least	ADJ
admet-505	1054	3	-	-	PUNCT
admet-505	1054	4	squares	square	NOUN
admet-505	1054	5	symmetric	symmetric	ADJ
admet-505	1054	6	matrix	matrix	NOUN
admet-505	1054	7	(	(	PUNCT
admet-505	1054	8	of	of	ADP
admet-505	1054	9	dimension	dimension	NOUN
admet-505	1054	10	equal	equal	ADJ
admet-505	1054	11	to	to	ADP
admet-505	1054	12	the	the	DET
admet-505	1054	13	number	number	NOUN
admet-505	1054	14	of	of	ADP
admet-505	1054	15	refined	refined	ADJ
admet-505	1054	16	parameters	parameter	NOUN
admet-505	1054	17	)	)	PUNCT
admet-505	1054	18	to	to	PART
admet-505	1054	19	be	be	AUX
admet-505	1054	20	inverted	invert	VERB
admet-505	1054	21	will	will	AUX
admet-505	1054	22	have	have	VERB
admet-505	1054	23	its	its	PRON
admet-505	1054	24	elements	element	NOUN
admet-505	1054	25	computed	compute	VERB
admet-505	1054	26	from	from	ADP
admet-505	1054	27	the	the	DET
admet-505	1054	28	first	first	ADJ
admet-505	1054	29	derivatives	derivative	NOUN
admet-505	1054	30	of	of	ADP
admet-505	1054	31	log	log	NOUN
admet-505	1054	32	ctot	ctot	NOUN
admet-505	1054	33	calc	calc	NOUN
admet-505	1054	34	with	with	ADP
admet-505	1054	35	respect	respect	NOUN
admet-505	1054	36	to	to	ADP
admet-505	1054	37	the	the	DET
admet-505	1054	38	adjustable	adjustable	ADJ
admet-505	1054	39	parameters	parameter	NOUN
admet-505	1054	40	(	(	PUNCT
admet-505	1054	41	related	relate	VERB
admet-505	1054	42	to	to	ADP
admet-505	1054	43	the	the	DET
admet-505	1054	44	‘	'	PUNCT
admet-505	1054	45	local	local	ADJ
admet-505	1054	46	’	'	PUNCT
admet-505	1054	47	inverse	inverse	ADJ
admet-505	1054	48	jacobian	jacobian	ADJ
admet-505	1054	49	matrix	matrix	NOUN
admet-505	1054	50	)	)	PUNCT
admet-505	1054	51	.	.	PUNCT
admet-505	1055	1	the	the	DET
admet-505	1055	2	partial	partial	ADJ
admet-505	1055	3	derivatives	derivative	NOUN
admet-505	1055	4	are	be	AUX
admet-505	1055	5	computed	compute	VERB
admet-505	1055	6	at	at	ADP
admet-505	1055	7	the	the	DET
admet-505	1055	8	‘	'	PUNCT
admet-505	1055	9	local	local	ADJ
admet-505	1055	10	’	'	PUNCT
admet-505	1055	11	refinement	refinement	NOUN
admet-505	1055	12	steps	step	NOUN
admet-505	1055	13	and	and	CCONJ
admet-505	1055	14	elements	element	NOUN
admet-505	1055	15	of	of	ADP
admet-505	1055	16	the	the	DET
admet-505	1055	17	global	global	ADJ
admet-505	1055	18	design	design	NOUN
admet-505	1055	19	matrix	matrix	NOUN
admet-505	1055	20	are	be	AUX
admet-505	1055	21	accumulated	accumulate	VERB
admet-505	1055	22	for	for	ADP
admet-505	1055	23	each	each	DET
admet-505	1055	24	ph	ph	NOUN
admet-505	1055	25	point	point	NOUN
admet-505	1055	26	.	.	PUNCT
admet-505	1056	1	when	when	SCONJ
admet-505	1056	2	all	all	DET
admet-505	1056	3	the	the	DET
admet-505	1056	4	data	data	NOUN
admet-505	1056	5	points	point	NOUN
admet-505	1056	6	have	have	AUX
admet-505	1056	7	been	be	AUX
admet-505	1056	8	processed	process	VERB
admet-505	1056	9	,	,	PUNCT
admet-505	1056	10	the	the	DET
admet-505	1056	11	accumulated	accumulate	VERB
admet-505	1056	12	matrix	matrix	NOUN
admet-505	1056	13	is	be	AUX
admet-505	1056	14	inverted	invert	VERB
admet-505	1056	15	and	and	CCONJ
admet-505	1056	16	the	the	DET
admet-505	1056	17	newly	newly	ADV
admet-505	1056	18	-	-	PUNCT
admet-505	1056	19	estimated	estimate	VERB
admet-505	1056	20	equilibrium	equilibrium	NOUN
admet-505	1056	21	constants	constant	NOUN
admet-505	1056	22	are	be	AUX
admet-505	1056	23	incrementally	incrementally	ADV
admet-505	1056	24	calculated	calculate	VERB
admet-505	1056	25	.	.	PUNCT
admet-505	1057	1	the	the	DET
admet-505	1057	2	iterative	iterative	NOUN
admet-505	1057	3	process	process	NOUN
admet-505	1057	4	continues	continue	VERB
admet-505	1057	5	until	until	SCONJ
admet-505	1057	6	the	the	DET
admet-505	1057	7	improvements	improvement	NOUN
admet-505	1057	8	are	be	AUX
admet-505	1057	9	vanishingly	vanishingly	ADV
admet-505	1057	10	small	small	ADJ
admet-505	1057	11	.	.	PUNCT
admet-505	1058	1	admet	admet	PROPN
admet-505	1058	2	&	&	CCONJ
admet-505	1058	3	dmpk	dmpk	PROPN
admet-505	1058	4	6(2	6(2	NUM
admet-505	1058	5	)	)	PUNCT
admet-505	1058	6	(	(	PUNCT
admet-505	1058	7	2018	2018	NUM
admet-505	1058	8	)	)	PUNCT
admet-505	1058	9	105	105	NUM
admet-505	1058	10	-	-	SYM
admet-505	1058	11	139	139	NUM
admet-505	1058	12	cocrystal	cocrystal	ADJ
admet-505	1058	13	solubility	solubility	NOUN
admet-505	1058	14	-	-	PUNCT
admet-505	1058	15	ph	ph	VERB
admet-505	1058	16	,	,	PUNCT
admet-505	1058	17	drug	drug	NOUN
admet-505	1058	18	solubilization	solubilization	NOUN
admet-505	1058	19	capacity	capacity	NOUN
admet-505	1058	20	of	of	ADP
admet-505	1058	21	sds	sds	PROPN
admet-505	1058	22	,	,	PUNCT
admet-505	1058	23	mass	mass	ADJ
admet-505	1058	24	action	action	NOUN
admet-505	1058	25	model	model	NOUN
admet-505	1058	26	doi	doi	PROPN
admet-505	1058	27	:	:	PUNCT
admet-505	1058	28	10.5599	10.5599	NUM
admet-505	1058	29	/	/	SYM
admet-505	1058	30	admet.505	admet.505	PROPN
admet-505	1058	31	139	139	NUM
admet-505	1058	32	weighting	weighting	NOUN
admet-505	1058	33	scheme	scheme	NOUN
admet-505	1058	34	and	and	CCONJ
admet-505	1058	35	goodness	goodness	NOUN
admet-505	1058	36	-	-	PUNCT
admet-505	1058	37	of	of	ADP
admet-505	1058	38	-	-	PUNCT
admet-505	1058	39	fit	fit	NOUN
admet-505	1058	40	,	,	PUNCT
admet-505	1058	41	gof	gof	NOUN
admet-505	1058	42	after	after	ADP
admet-505	1058	43	each	each	DET
admet-505	1058	44	global	global	ADJ
admet-505	1058	45	iterative	iterative	NOUN
admet-505	1058	46	cycle	cycle	NOUN
admet-505	1058	47	,	,	PUNCT
admet-505	1058	48	the	the	DET
admet-505	1058	49	progress	progress	NOUN
admet-505	1058	50	of	of	ADP
admet-505	1058	51	refinement	refinement	NOUN
admet-505	1058	52	is	be	AUX
admet-505	1058	53	indicated	indicate	VERB
admet-505	1058	54	by	by	ADP
admet-505	1058	55	the	the	DET
admet-505	1058	56	‘	'	PUNCT
admet-505	1058	57	goodness	goodness	NOUN
admet-505	1058	58	-	-	PUNCT
admet-505	1058	59	of	of	ADP
admet-505	1058	60	-	-	PUNCT
admet-505	1058	61	fit	fit	NOUN
admet-505	1058	62	’	'	PUNCT
admet-505	1058	63	,	,	PUNCT
admet-505	1058	64	gof	gof	NOUN
admet-505	1058	65	,	,	PUNCT
admet-505	1058	66	as	as	ADP
admet-505	1058	67	v	v	ADP
admet-505	1058	68	cof	cof	PROPN
admet-505	1058	69	w	w	PROPN
admet-505	1058	70	nnn	nnn	PROPN
admet-505	1058	71	r	r	NOUN
admet-505	1058	72	gof	gof	NOUN
admet-505	1058	73			PROPN
admet-505	1058	74			PROPN
admet-505	1058	75	00	00	PUNCT
admet-505	1059	1	(	(	PUNCT
admet-505	1059	2	a.2	a.2	PROPN
admet-505	1059	3	)	)	PUNCT
admet-505	1059	4	where	where	SCONJ
admet-505	1059	5	nv	nv	PROPN
admet-505	1059	6	is	be	AUX
admet-505	1059	7	the	the	DET
admet-505	1059	8	number	number	NOUN
admet-505	1059	9	of	of	ADP
admet-505	1059	10	varied	varied	ADJ
admet-505	1059	11	equilibrium	equilibrium	NOUN
admet-505	1059	12	constants	constant	NOUN
admet-505	1059	13	.	.	PUNCT
admet-505	1060	1	gof	gof	ADJ
admet-505	1060	2	values	value	NOUN
admet-505	1060	3	of	of	ADP
admet-505	1060	4	1	1	NUM
admet-505	1060	5	are	be	AUX
admet-505	1060	6	ideal	ideal	ADJ
admet-505	1060	7	.	.	PUNCT
admet-505	1061	1	it	it	PRON
admet-505	1061	2	would	would	AUX
admet-505	1061	3	mean	mean	VERB
admet-505	1061	4	that	that	SCONJ
admet-505	1061	5	on	on	ADP
admet-505	1061	6	the	the	DET
admet-505	1061	7	average	average	NOUN
admet-505	1061	8	,	,	PUNCT
admet-505	1061	9	the	the	DET
admet-505	1061	10	calculated	calculate	VERB
admet-505	1061	11	and	and	CCONJ
admet-505	1061	12	observed	observe	VERB
admet-505	1061	13	log	log	NOUN
admet-505	1061	14	ctot	ctot	ADJ
admet-505	1061	15	ph	ph	NOUN
admet-505	1061	16	curves	curve	NOUN
admet-505	1061	17	are	be	AUX
admet-505	1061	18	about	about	ADV
admet-505	1061	19	one	one	NUM
admet-505	1061	20	standard	standard	ADJ
admet-505	1061	21	deviation	deviation	NOUN
admet-505	1061	22	(	(	PUNCT
admet-505	1061	23	0.05	0.05	NUM
admet-505	1061	24	-	-	SYM
admet-505	1061	25	0.1	0.1	NUM
admet-505	1061	26	log	log	NOUN
admet-505	1061	27	unit	unit	NOUN
admet-505	1061	28	)	)	PUNCT
admet-505	1061	29	apart	apart	ADV
admet-505	1061	30	.	.	PUNCT
admet-505	1062	1	gof	gof	PROPN
admet-505	1062	2	0.5	0.5	NUM
admet-505	1062	3	-	-	SYM
admet-505	1062	4	1.5	1.5	NUM
admet-505	1062	5	is	be	AUX
admet-505	1062	6	often	often	ADV
admet-505	1062	7	obtained	obtain	VERB
admet-505	1062	8	for	for	ADP
admet-505	1062	9	successful	successful	ADJ
admet-505	1062	10	refinement	refinement	NOUN
admet-505	1062	11	.	.	PUNCT
admet-505	1063	1	gof	gof	NOUN
admet-505	1063	2	>	>	X
admet-505	1063	3	>	>	X
admet-505	1063	4	2	2	NUM
admet-505	1063	5	indicates	indicate	VERB
admet-505	1063	6	that	that	SCONJ
admet-505	1063	7	log	log	NOUN
admet-505	1063	8	ctot	ctot	NOUN
admet-505	1063	9	measurements	measurement	NOUN
admet-505	1063	10	are	be	AUX
admet-505	1063	11	of	of	ADP
admet-505	1063	12	poor	poor	ADJ
admet-505	1063	13	quality	quality	NOUN
admet-505	1063	14	,	,	PUNCT
admet-505	1063	15	or	or	CCONJ
admet-505	1063	16	the	the	DET
admet-505	1063	17	experimental	experimental	ADJ
admet-505	1063	18	standard	standard	ADJ
admet-505	1063	19	deviations	deviation	NOUN
admet-505	1063	20	are	be	AUX
admet-505	1063	21	underestimated	underestimate	VERB
admet-505	1063	22	,	,	PUNCT
admet-505	1063	23	or	or	CCONJ
admet-505	1063	24	the	the	DET
admet-505	1063	25	assumed	assume	VERB
admet-505	1063	26	equilibrium	equilibrium	NOUN
admet-505	1063	27	model	model	NOUN
admet-505	1063	28	is	be	AUX
admet-505	1063	29	incomplete	incomplete	ADJ
admet-505	1063	30	or	or	CCONJ
admet-505	1063	31	inappropriate	inappropriate	ADJ
admet-505	1063	32	.	.	PUNCT
admet-505	1064	1	©	©	PROPN
admet-505	1064	2	2018	2018	NUM
admet-505	1064	3	by	by	ADP
admet-505	1064	4	the	the	DET
admet-505	1064	5	authors	author	NOUN
admet-505	1064	6	;	;	PUNCT
admet-505	1065	1	licensee	licensee	PROPN
admet-505	1065	2	iapc	iapc	PROPN
admet-505	1065	3	,	,	PUNCT
admet-505	1065	4	zagreb	zagreb	PROPN
admet-505	1065	5	,	,	PUNCT
admet-505	1065	6	croatia	croatia	PROPN
admet-505	1065	7	.	.	PUNCT
admet-505	1066	1	this	this	DET
admet-505	1066	2	article	article	NOUN
admet-505	1066	3	is	be	AUX
admet-505	1066	4	an	an	DET
admet-505	1066	5	open	open	ADJ
admet-505	1066	6	-	-	PUNCT
admet-505	1066	7	access	access	NOUN
admet-505	1066	8	article	article	NOUN
admet-505	1066	9	distributed	distribute	VERB
admet-505	1066	10	under	under	ADP
admet-505	1066	11	the	the	DET
admet-505	1066	12	terms	term	NOUN
admet-505	1066	13	and	and	CCONJ
admet-505	1066	14	conditions	condition	NOUN
admet-505	1066	15	of	of	ADP
admet-505	1066	16	the	the	DET
admet-505	1066	17	creative	creative	ADJ
admet-505	1066	18	commons	common	NOUN
admet-505	1066	19	attribution	attribution	NOUN
admet-505	1066	20	license	license	NOUN
admet-505	1066	21	(	(	PUNCT
admet-505	1066	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-505	1066	23	)	)	PUNCT
admet-505	1066	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN