id	sid	tid	token	lemma	pos
admet-510	1	1	feasibility	feasibility	NOUN
admet-510	1	2	of	of	ADP
admet-510	1	3	the	the	DET
admet-510	1	4	estimation	estimation	NOUN
admet-510	1	5	of	of	ADP
admet-510	1	6	octanol	octanol	NOUN
admet-510	1	7	-	-	PUNCT
admet-510	1	8	water	water	NOUN
admet-510	1	9	distribution	distribution	NOUN
admet-510	1	10	coefficients	coefficient	NOUN
admet-510	1	11	of	of	ADP
admet-510	1	12	acidic	acidic	ADJ
admet-510	1	13	drugs	drug	NOUN
admet-510	1	14	by	by	ADP
admet-510	1	15	microemulsion	microemulsion	NOUN
admet-510	1	16	electrokinetic	electrokinetic	ADJ
admet-510	1	17	chromatography	chromatography	NOUN
admet-510	1	18	doi	doi	NOUN
admet-510	1	19	:	:	PUNCT
admet-510	1	20	10.5599	10.5599	NUM
admet-510	1	21	/	/	SYM
admet-510	1	22	admet.6.1.510	admet.6.1.510	NUM
admet-510	1	23	55	55	NUM
admet-510	1	24	admet	admet	NOUN
admet-510	1	25	&	&	CCONJ
admet-510	1	26	dmpk	dmpk	PROPN
admet-510	1	27	6(1	6(1	NUM
admet-510	1	28	)	)	PUNCT
admet-510	1	29	(	(	PUNCT
admet-510	1	30	2018	2018	NUM
admet-510	1	31	)	)	PUNCT
admet-510	1	32	55	55	NUM
admet-510	1	33	-	-	SYM
admet-510	1	34	60	60	NUM
admet-510	1	35	;	;	PUNCT
admet-510	1	36	doi	doi	NOUN
admet-510	1	37	:	:	PUNCT
admet-510	1	38	http://dx.doi.org/10.5599/admet.6.1.510	http://dx.doi.org/10.5599/admet.6.1.510	NUM
admet-510	1	39	open	open	ADJ
admet-510	1	40	access	access	NOUN
admet-510	1	41	:	:	PUNCT
admet-510	1	42	issn	issn	PROPN
admet-510	1	43	:	:	PUNCT
admet-510	1	44	1848	1848	NUM
admet-510	1	45	-	-	SYM
admet-510	1	46	7718	7718	NUM
admet-510	1	47	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-510	1	48	short	short	ADJ
admet-510	1	49	communication	communication	NOUN
admet-510	1	50	feasibility	feasibility	NOUN
admet-510	1	51	of	of	ADP
admet-510	1	52	the	the	DET
admet-510	1	53	estimation	estimation	NOUN
admet-510	1	54	of	of	ADP
admet-510	1	55	octanol	octanol	NOUN
admet-510	1	56	-	-	PUNCT
admet-510	1	57	water	water	NOUN
admet-510	1	58	distribution	distribution	NOUN
admet-510	1	59	coefficients	coefficient	NOUN
admet-510	1	60	of	of	ADP
admet-510	1	61	acidic	acidic	ADJ
admet-510	1	62	drugs	drug	NOUN
admet-510	1	63	by	by	ADP
admet-510	1	64	microemulsion	microemulsion	NOUN
admet-510	1	65	electrokinetic	electrokinetic	ADJ
admet-510	1	66	chromatography	chromatography	NOUN
admet-510	1	67	alejandro	alejandro	PROPN
admet-510	1	68	fernández	fernández	PROPN
admet-510	1	69	-	-	PUNCT
admet-510	1	70	pumarega1	pumarega1	PROPN
admet-510	1	71	,	,	PUNCT
admet-510	1	72	susana	susana	PROPN
admet-510	1	73	amézqueta1	amézqueta1	PROPN
admet-510	1	74	,	,	PUNCT
admet-510	1	75	*	*	PUNCT
admet-510	1	76	,	,	PUNCT
admet-510	1	77	elisabet	elisabet	PROPN
admet-510	1	78	fuguet1,2	fuguet1,2	PROPN
admet-510	1	79	,	,	PUNCT
admet-510	1	80	martí	martí	NOUN
admet-510	1	81	rosés1	rosés1	ADJ
admet-510	1	82	1	1	NUM
admet-510	1	83	departament	departament	NOUN
admet-510	1	84	de	de	PROPN
admet-510	1	85	química	química	PROPN
admet-510	1	86	analítica	analítica	PROPN
admet-510	1	87	and	and	CCONJ
admet-510	1	88	institute	institute	PROPN
admet-510	1	89	of	of	ADP
admet-510	1	90	biomedicine	biomedicine	NOUN
admet-510	1	91	of	of	ADP
admet-510	1	92	the	the	DET
admet-510	1	93	university	university	PROPN
admet-510	1	94	of	of	ADP
admet-510	1	95	barcelona	barcelona	PROPN
admet-510	1	96	(	(	PUNCT
admet-510	1	97	ibub	ibub	PROPN
admet-510	1	98	)	)	PUNCT
admet-510	1	99	,	,	PUNCT
admet-510	1	100	universitat	universitat	PROPN
admet-510	1	101	de	de	PROPN
admet-510	1	102	barcelona	barcelona	PROPN
admet-510	1	103	,	,	PUNCT
admet-510	1	104	martí	martí	NOUN
admet-510	1	105	i	i	PRON
admet-510	1	106	franquès	franquès	VERB
admet-510	1	107	1	1	NUM
admet-510	1	108	-	-	SYM
admet-510	1	109	11	11	NUM
admet-510	1	110	,	,	PUNCT
admet-510	1	111	08028	08028	NUM
admet-510	1	112	,	,	PUNCT
admet-510	1	113	barcelona	barcelona	PROPN
admet-510	1	114	,	,	PUNCT
admet-510	1	115	spain	spain	PROPN
admet-510	1	116	2	2	NUM
admet-510	1	117	serra	serra	PROPN
admet-510	1	118	húnter	húnter	PROPN
admet-510	1	119	programme	programme	PROPN
admet-510	1	120	,	,	PUNCT
admet-510	1	121	generalitat	generalitat	PROPN
admet-510	1	122	de	de	PROPN
admet-510	1	123	catalunya	catalunya	PROPN
admet-510	1	124	*	*	PUNCT
admet-510	1	125	corresponding	correspond	VERB
admet-510	1	126	author	author	NOUN
admet-510	1	127	:	:	PUNCT
admet-510	1	128	e	e	NOUN
admet-510	1	129	-	-	NOUN
admet-510	1	130	mail	mail	NOUN
admet-510	1	131	:	:	PUNCT
admet-510	1	132	samezqueta@ub.edu	samezqueta@ub.edu	NOUN
admet-510	1	133	;	;	PUNCT
admet-510	1	134	tel.:+34934021277	tel.:+34934021277	PRON
admet-510	1	135	received	receive	VERB
admet-510	1	136	:	:	PUNCT
admet-510	1	137	february	february	PROPN
admet-510	1	138	19	19	NUM
admet-510	1	139	,	,	PUNCT
admet-510	1	140	2018	2018	NUM
admet-510	1	141	;	;	PUNCT
admet-510	1	142	revised	revise	VERB
admet-510	1	143	:	:	PUNCT
admet-510	1	144	march	march	PROPN
admet-510	1	145	18	18	NUM
admet-510	1	146	,	,	PUNCT
admet-510	1	147	2018	2018	NUM
admet-510	1	148	;	;	PUNCT
admet-510	1	149	published	publish	VERB
admet-510	1	150	:	:	PUNCT
admet-510	1	151	march	march	PROPN
admet-510	1	152	25	25	NUM
admet-510	1	153	,	,	PUNCT
admet-510	1	154	2018	2018	NUM
admet-510	1	155	abstract	abstract	ADJ
admet-510	1	156	previous	previous	ADJ
admet-510	1	157	studies	study	NOUN
admet-510	1	158	have	have	AUX
admet-510	1	159	shown	show	VERB
admet-510	1	160	that	that	SCONJ
admet-510	1	161	a	a	DET
admet-510	1	162	microemulsion	microemulsion	NOUN
admet-510	1	163	electrokinetic	electrokinetic	ADJ
admet-510	1	164	chromatography	chromatography	NOUN
admet-510	1	165	(	(	PUNCT
admet-510	1	166	meekc	meekc	NOUN
admet-510	1	167	)	)	PUNCT
admet-510	1	168	system	system	NOUN
admet-510	1	169	can	can	AUX
admet-510	1	170	estimate	estimate	VERB
admet-510	1	171	the	the	DET
admet-510	1	172	logarithm	logarithm	NOUN
admet-510	1	173	of	of	ADP
admet-510	1	174	the	the	DET
admet-510	1	175	octanol	octanol	NOUN
admet-510	1	176	-	-	PUNCT
admet-510	1	177	water	water	NOUN
admet-510	1	178	partition	partition	NOUN
admet-510	1	179	coefficient	coefficient	NOUN
admet-510	1	180	(	(	PUNCT
admet-510	1	181	log	log	VERB
admet-510	1	182	po	po	PROPN
admet-510	1	183	/	/	SYM
admet-510	1	184	w	w	NOUN
admet-510	1	185	)	)	PUNCT
admet-510	1	186	of	of	ADP
admet-510	1	187	neutral	neutral	ADJ
admet-510	1	188	solutes	solute	NOUN
admet-510	1	189	.	.	PUNCT
admet-510	2	1	in	in	ADP
admet-510	2	2	the	the	DET
admet-510	2	3	present	present	ADJ
admet-510	2	4	work	work	NOUN
admet-510	2	5	,	,	PUNCT
admet-510	2	6	the	the	DET
admet-510	2	7	applicability	applicability	NOUN
admet-510	2	8	of	of	ADP
admet-510	2	9	the	the	DET
admet-510	2	10	method	method	NOUN
admet-510	2	11	to	to	PART
admet-510	2	12	partially	partially	ADV
admet-510	2	13	and	and	CCONJ
admet-510	2	14	fully	fully	ADV
admet-510	2	15	ionized	ionized	ADJ
admet-510	2	16	acids	acid	NOUN
admet-510	2	17	has	have	AUX
admet-510	2	18	been	be	AUX
admet-510	2	19	evaluated	evaluate	VERB
admet-510	2	20	.	.	PUNCT
admet-510	3	1	naproxen	naproxen	NOUN
admet-510	3	2	,	,	PUNCT
admet-510	3	3	a	a	DET
admet-510	3	4	monoprotic	monoprotic	ADJ
admet-510	3	5	acid	acid	NOUN
admet-510	3	6	,	,	PUNCT
admet-510	3	7	has	have	AUX
admet-510	3	8	been	be	AUX
admet-510	3	9	used	use	VERB
admet-510	3	10	as	as	ADP
admet-510	3	11	test	test	NOUN
admet-510	3	12	solute	solute	NOUN
admet-510	3	13	.	.	PUNCT
admet-510	4	1	the	the	DET
admet-510	4	2	retention	retention	NOUN
admet-510	4	3	factor	factor	NOUN
admet-510	4	4	(	(	PUNCT
admet-510	4	5	k	k	NOUN
admet-510	4	6	)	)	PUNCT
admet-510	4	7	of	of	ADP
admet-510	4	8	this	this	DET
admet-510	4	9	compound	compound	NOUN
admet-510	4	10	has	have	AUX
admet-510	4	11	been	be	AUX
admet-510	4	12	measured	measure	VERB
admet-510	4	13	in	in	ADP
admet-510	4	14	meekc	meekc	NOUN
admet-510	4	15	at	at	ADP
admet-510	4	16	several	several	ADJ
admet-510	4	17	values	value	NOUN
admet-510	4	18	of	of	ADP
admet-510	4	19	ph	ph	NOUN
admet-510	4	20	and	and	CCONJ
admet-510	4	21	the	the	DET
admet-510	4	22	retention	retention	NOUN
admet-510	4	23	factor	factor	NOUN
admet-510	4	24	-	-	PUNCT
admet-510	4	25	ph	ph	NOUN
admet-510	4	26	profile	profile	NOUN
admet-510	4	27	has	have	AUX
admet-510	4	28	been	be	AUX
admet-510	4	29	established	establish	VERB
admet-510	4	30	.	.	PUNCT
admet-510	5	1	as	as	SCONJ
admet-510	5	2	log	log	PROPN
admet-510	5	3	po	po	PROPN
admet-510	5	4	/	/	SYM
admet-510	5	5	w	w	PROPN
admet-510	5	6	correlates	correlate	VERB
admet-510	5	7	with	with	ADP
admet-510	5	8	log	log	PROPN
admet-510	5	9	kmeekc	kmeekc	NOUN
admet-510	5	10	for	for	ADP
admet-510	5	11	neutral	neutral	ADJ
admet-510	5	12	compounds	compound	NOUN
admet-510	5	13	,	,	PUNCT
admet-510	5	14	this	this	DET
admet-510	5	15	correlation	correlation	NOUN
admet-510	5	16	has	have	AUX
admet-510	5	17	been	be	AUX
admet-510	5	18	used	use	VERB
admet-510	5	19	to	to	PART
admet-510	5	20	estimate	estimate	VERB
admet-510	5	21	the	the	DET
admet-510	5	22	logarithm	logarithm	NOUN
admet-510	5	23	of	of	ADP
admet-510	5	24	the	the	DET
admet-510	5	25	octanol	octanol	NOUN
admet-510	5	26	-	-	PUNCT
admet-510	5	27	water	water	NOUN
admet-510	5	28	partition	partition	NOUN
admet-510	5	29	coefficient	coefficient	NOUN
admet-510	5	30	of	of	ADP
admet-510	5	31	the	the	DET
admet-510	5	32	neutral	neutral	ADJ
admet-510	5	33	(	(	PUNCT
admet-510	5	34	log	log	NOUN
admet-510	5	35	po	po	NOUN
admet-510	5	36	/	/	SYM
admet-510	5	37	w(ha	w(ha	NOUN
admet-510	5	38	)	)	PUNCT
admet-510	5	39	)	)	PUNCT
admet-510	5	40	,	,	PUNCT
admet-510	5	41	and	and	CCONJ
admet-510	5	42	the	the	DET
admet-510	5	43	fully	fully	ADV
admet-510	5	44	ionized	ionized	ADJ
admet-510	5	45	(	(	PUNCT
admet-510	5	46	log	log	VERB
admet-510	5	47	p	p	NOUN
admet-510	5	48	o	o	NOUN
admet-510	5	49	/	/	SYM
admet-510	5	50	w(a-	w(a-	PROPN
admet-510	5	51	)	)	PUNCT
admet-510	5	52	)	)	PUNCT
admet-510	5	53	forms	form	NOUN
admet-510	5	54	of	of	ADP
admet-510	5	55	naproxen	naproxen	NOUN
admet-510	5	56	.	.	PUNCT
admet-510	6	1	then	then	ADV
admet-510	6	2	,	,	PUNCT
admet-510	6	3	the	the	DET
admet-510	6	4	logarithm	logarithm	NOUN
admet-510	6	5	of	of	ADP
admet-510	6	6	the	the	DET
admet-510	6	7	octanol	octanol	NOUN
admet-510	6	8	-	-	PUNCT
admet-510	6	9	water	water	NOUN
admet-510	6	10	distribution	distribution	NOUN
admet-510	6	11	coefficient	coefficient	NOUN
admet-510	6	12	(	(	PUNCT
admet-510	6	13	log	log	NOUN
admet-510	6	14	do	do	AUX
admet-510	6	15	/	/	SYM
admet-510	6	16	w	w	NOUN
admet-510	6	17	)	)	PUNCT
admet-510	6	18	of	of	ADP
admet-510	6	19	the	the	DET
admet-510	6	20	partially	partially	ADV
admet-510	6	21	ionized	ionized	ADJ
admet-510	6	22	form	form	NOUN
admet-510	6	23	of	of	ADP
admet-510	6	24	the	the	DET
admet-510	6	25	acid	acid	NOUN
admet-510	6	26	has	have	AUX
admet-510	6	27	been	be	AUX
admet-510	6	28	estimated	estimate	VERB
admet-510	6	29	.	.	PUNCT
admet-510	7	1	the	the	DET
admet-510	7	2	comparison	comparison	NOUN
admet-510	7	3	of	of	ADP
admet-510	7	4	the	the	DET
admet-510	7	5	estimated	estimate	VERB
admet-510	7	6	values	value	NOUN
admet-510	7	7	with	with	ADP
admet-510	7	8	the	the	DET
admet-510	7	9	ones	one	NOUN
admet-510	7	10	obtained	obtain	VERB
admet-510	7	11	experimentally	experimentally	ADV
admet-510	7	12	using	use	VERB
admet-510	7	13	the	the	DET
admet-510	7	14	classical	classical	ADJ
admet-510	7	15	procedures	procedure	NOUN
admet-510	7	16	,	,	PUNCT
admet-510	7	17	such	such	ADJ
admet-510	7	18	as	as	ADP
admet-510	7	19	the	the	DET
admet-510	7	20	shake	shake	NOUN
admet-510	7	21	-	-	PUNCT
admet-510	7	22	flask	flask	NOUN
admet-510	7	23	method	method	NOUN
admet-510	7	24	,	,	PUNCT
admet-510	7	25	shows	show	VERB
admet-510	7	26	differences	difference	NOUN
admet-510	7	27	under	under	ADP
admet-510	7	28	0.4	0.4	NUM
admet-510	7	29	log	log	NOUN
admet-510	7	30	do	do	AUX
admet-510	7	31	/	/	SYM
admet-510	7	32	w	w	NOUN
admet-510	7	33	units	unit	NOUN
admet-510	7	34	either	either	CCONJ
admet-510	7	35	if	if	SCONJ
admet-510	7	36	the	the	DET
admet-510	7	37	acid	acid	NOUN
admet-510	7	38	is	be	AUX
admet-510	7	39	partially	partially	ADV
admet-510	7	40	ionized	ionized	ADJ
admet-510	7	41	or	or	CCONJ
admet-510	7	42	in	in	ADP
admet-510	7	43	its	its	PRON
admet-510	7	44	neutral	neutral	ADJ
admet-510	7	45	form	form	NOUN
admet-510	7	46	in	in	ADP
admet-510	7	47	the	the	DET
admet-510	7	48	most	most	ADJ
admet-510	7	49	part	part	NOUN
admet-510	7	50	of	of	ADP
admet-510	7	51	the	the	DET
admet-510	7	52	ph	ph	ADJ
admet-510	7	53	range	range	NOUN
admet-510	7	54	.	.	PUNCT
admet-510	8	1	however	however	ADV
admet-510	8	2	,	,	PUNCT
admet-510	8	3	the	the	DET
admet-510	8	4	method	method	NOUN
admet-510	8	5	overestimates	overestimate	VERB
admet-510	8	6	the	the	DET
admet-510	8	7	log	log	NOUN
admet-510	8	8	do	do	AUX
admet-510	8	9	/	/	SYM
admet-510	8	10	w	w	NOUN
admet-510	8	11	of	of	ADP
admet-510	8	12	the	the	DET
admet-510	8	13	highly	highly	ADV
admet-510	8	14	(	(	PUNCT
admet-510	8	15	>	>	SYM
admet-510	8	16	99.5	99.5	NUM
admet-510	8	17	%	%	NOUN
admet-510	8	18	)	)	PUNCT
admet-510	8	19	or	or	CCONJ
admet-510	8	20	fully	fully	ADV
admet-510	8	21	ionized	ionized	ADJ
admet-510	8	22	form	form	NOUN
admet-510	8	23	of	of	ADP
admet-510	8	24	naproxen	naproxen	NOUN
admet-510	8	25	.	.	PUNCT
admet-510	9	1	keywords	keyword	NOUN
admet-510	9	2	capillary	capillary	ADJ
admet-510	9	3	electrophoresis	electrophoresis	NOUN
admet-510	9	4	;	;	PUNCT
admet-510	9	5	meekc	meekc	VERB
admet-510	9	6	;	;	PUNCT
admet-510	9	7	log	log	VERB
admet-510	9	8	do	do	AUX
admet-510	9	9	/	/	SYM
admet-510	9	10	w	w	PROPN
admet-510	9	11	;	;	PUNCT
admet-510	9	12	lipophilicity	lipophilicity	NOUN
admet-510	9	13	introduction	introduction	NOUN
admet-510	9	14	lipophilicity	lipophilicity	NOUN
admet-510	9	15	,	,	PUNCT
admet-510	9	16	which	which	PRON
admet-510	9	17	is	be	AUX
admet-510	9	18	defined	define	VERB
admet-510	9	19	as	as	ADP
admet-510	9	20	the	the	DET
admet-510	9	21	ability	ability	NOUN
admet-510	9	22	of	of	ADP
admet-510	9	23	a	a	DET
admet-510	9	24	compound	compound	NOUN
admet-510	9	25	to	to	PART
admet-510	9	26	be	be	AUX
admet-510	9	27	dissolved	dissolve	VERB
admet-510	9	28	in	in	ADP
admet-510	9	29	lipids	lipid	NOUN
admet-510	9	30	or	or	CCONJ
admet-510	9	31	non	non	ADJ
admet-510	9	32	-	-	ADJ
admet-510	9	33	polar	polar	ADJ
admet-510	9	34	solvents	solvent	NOUN
admet-510	9	35	,	,	PUNCT
admet-510	9	36	is	be	AUX
admet-510	9	37	a	a	DET
admet-510	9	38	key	key	ADJ
admet-510	9	39	factor	factor	NOUN
admet-510	9	40	in	in	ADP
admet-510	9	41	drug	drug	NOUN
admet-510	9	42	discovery	discovery	NOUN
admet-510	9	43	.	.	PUNCT
admet-510	10	1	this	this	DET
admet-510	10	2	property	property	NOUN
admet-510	10	3	,	,	PUNCT
admet-510	10	4	among	among	ADP
admet-510	10	5	others	other	NOUN
admet-510	10	6	,	,	PUNCT
admet-510	10	7	is	be	AUX
admet-510	10	8	related	relate	VERB
admet-510	10	9	to	to	ADP
admet-510	10	10	the	the	DET
admet-510	10	11	capacity	capacity	NOUN
admet-510	10	12	of	of	ADP
admet-510	10	13	a	a	DET
admet-510	10	14	substance	substance	NOUN
admet-510	10	15	to	to	PART
admet-510	10	16	pass	pass	VERB
admet-510	10	17	through	through	ADP
admet-510	10	18	different	different	ADJ
admet-510	10	19	biological	biological	ADJ
admet-510	10	20	membranes	membrane	NOUN
admet-510	10	21	,	,	PUNCT
admet-510	10	22	which	which	PRON
admet-510	10	23	are	be	AUX
admet-510	10	24	formed	form	VERB
admet-510	10	25	mainly	mainly	ADV
admet-510	10	26	by	by	ADP
admet-510	10	27	a	a	DET
admet-510	10	28	lipid	lipid	NOUN
admet-510	10	29	bilayer	bilayer	NOUN
admet-510	10	30	.	.	PUNCT
admet-510	11	1	therefore	therefore	ADV
admet-510	11	2	,	,	PUNCT
admet-510	11	3	the	the	DET
admet-510	11	4	viability	viability	NOUN
admet-510	11	5	of	of	ADP
admet-510	11	6	a	a	DET
admet-510	11	7	compound	compound	NOUN
admet-510	11	8	as	as	ADP
admet-510	11	9	a	a	DET
admet-510	11	10	drug	drug	NOUN
admet-510	11	11	candidate	candidate	NOUN
admet-510	11	12	is	be	AUX
admet-510	11	13	clearly	clearly	ADV
admet-510	11	14	linked	link	VERB
admet-510	11	15	to	to	ADP
admet-510	11	16	its	its	PRON
admet-510	11	17	lipophilicity	lipophilicity	NOUN
admet-510	11	18	.	.	PUNCT
admet-510	12	1	in	in	ADP
admet-510	12	2	order	order	NOUN
admet-510	12	3	to	to	PART
admet-510	12	4	estimate	estimate	VERB
admet-510	12	5	the	the	DET
admet-510	12	6	lipophilicity	lipophilicity	NOUN
admet-510	12	7	of	of	ADP
admet-510	12	8	a	a	DET
admet-510	12	9	substance	substance	NOUN
admet-510	12	10	,	,	PUNCT
admet-510	12	11	different	different	ADJ
admet-510	12	12	parameters	parameter	NOUN
admet-510	12	13	can	can	AUX
admet-510	12	14	be	be	AUX
admet-510	12	15	evaluated	evaluate	VERB
admet-510	12	16	.	.	PUNCT
admet-510	13	1	among	among	ADP
admet-510	13	2	these	these	PRON
admet-510	13	3	,	,	PUNCT
admet-510	13	4	the	the	DET
admet-510	13	5	most	most	ADV
admet-510	13	6	widely	widely	ADV
admet-510	13	7	used	use	VERB
admet-510	13	8	is	be	AUX
admet-510	13	9	the	the	DET
admet-510	13	10	octanol	octanol	NOUN
admet-510	13	11	-	-	PUNCT
admet-510	13	12	water	water	NOUN
admet-510	13	13	partition	partition	NOUN
admet-510	13	14	coefficient	coefficient	NOUN
admet-510	13	15	(	(	PUNCT
admet-510	13	16	po	po	NOUN
admet-510	13	17	/	/	SYM
admet-510	13	18	w	w	PROPN
admet-510	13	19	)	)	PUNCT
admet-510	13	20	.	.	PUNCT
admet-510	14	1	however	however	ADV
admet-510	14	2	,	,	PUNCT
admet-510	14	3	the	the	DET
admet-510	14	4	direct	direct	ADJ
admet-510	14	5	evaluation	evaluation	NOUN
admet-510	14	6	of	of	ADP
admet-510	14	7	this	this	DET
admet-510	14	8	parameter	parameter	NOUN
admet-510	14	9	(	(	PUNCT
admet-510	14	10	following	follow	VERB
admet-510	14	11	the	the	DET
admet-510	14	12	shake	shake	NOUN
admet-510	14	13	-	-	PUNCT
admet-510	14	14	flask	flask	NOUN
admet-510	14	15	method	method	NOUN
admet-510	14	16	)	)	PUNCT
admet-510	14	17	is	be	AUX
admet-510	14	18	time	time	NOUN
admet-510	14	19	-	-	PUNCT
admet-510	14	20	consuming	consume	VERB
admet-510	14	21	and	and	CCONJ
admet-510	14	22	it	it	PRON
admet-510	14	23	is	be	AUX
admet-510	14	24	not	not	PART
admet-510	14	25	fully	fully	ADV
admet-510	14	26	automated	automate	VERB
admet-510	14	27	.	.	PUNCT
admet-510	15	1	because	because	SCONJ
admet-510	15	2	of	of	ADP
admet-510	15	3	these	these	DET
admet-510	15	4	drawbacks	drawback	NOUN
admet-510	15	5	,	,	PUNCT
admet-510	15	6	the	the	DET
admet-510	15	7	development	development	NOUN
admet-510	15	8	of	of	ADP
admet-510	15	9	faster	fast	ADJ
admet-510	15	10	high	high	ADJ
admet-510	15	11	-	-	PUNCT
admet-510	15	12	throughput	throughput	NOUN
admet-510	15	13	methods	method	NOUN
admet-510	15	14	is	be	AUX
admet-510	15	15	of	of	ADP
admet-510	15	16	a	a	DET
admet-510	15	17	great	great	ADJ
admet-510	15	18	interest	interest	NOUN
admet-510	15	19	.	.	PUNCT
admet-510	16	1	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-510	16	2	mailto:samezqueta@ub.edu	mailto:samezqueta@ub.edu	PUNCT
admet-510	17	1	susana	susana	PROPN
admet-510	17	2	amézqueta	amézqueta	PROPN
admet-510	17	3	et	et	PROPN
admet-510	17	4	al	al	PROPN
admet-510	17	5	.	.	PROPN
admet-510	17	6	admet	admet	PROPN
admet-510	17	7	&	&	CCONJ
admet-510	17	8	dmpk	dmpk	PROPN
admet-510	17	9	6(1	6(1	NUM
admet-510	17	10	)	)	PUNCT
admet-510	17	11	(	(	PUNCT
admet-510	17	12	2018	2018	NUM
admet-510	17	13	)	)	PUNCT
admet-510	17	14	55	55	NUM
admet-510	17	15	-	-	SYM
admet-510	17	16	60	60	NUM
admet-510	17	17	56	56	NUM
admet-510	17	18	ishihama	ishihama	NOUN
admet-510	17	19	and	and	CCONJ
admet-510	17	20	coworkers	coworker	NOUN
admet-510	18	1	[	[	X
admet-510	18	2	1	1	X
admet-510	18	3	]	]	PUNCT
admet-510	18	4	introduced	introduce	VERB
admet-510	18	5	a	a	DET
admet-510	18	6	method	method	NOUN
admet-510	18	7	able	able	ADJ
admet-510	18	8	to	to	PART
admet-510	18	9	evaluate	evaluate	VERB
admet-510	18	10	the	the	DET
admet-510	18	11	lipophilicity	lipophilicity	NOUN
admet-510	18	12	of	of	ADP
admet-510	18	13	a	a	DET
admet-510	18	14	substance	substance	NOUN
admet-510	18	15	through	through	ADP
admet-510	18	16	a	a	DET
admet-510	18	17	system	system	NOUN
admet-510	18	18	based	base	VERB
admet-510	18	19	on	on	ADP
admet-510	18	20	microemulsion	microemulsion	PROPN
admet-510	18	21	electrokinetic	electrokinetic	ADJ
admet-510	18	22	chromatography	chromatography	NOUN
admet-510	18	23	(	(	PUNCT
admet-510	18	24	meekc	meekc	PROPN
admet-510	18	25	)	)	PUNCT
admet-510	18	26	.	.	PUNCT
admet-510	19	1	the	the	DET
admet-510	19	2	meekc	meekc	ADJ
admet-510	19	3	system	system	NOUN
admet-510	19	4	used	use	VERB
admet-510	19	5	is	be	AUX
admet-510	19	6	composed	compose	VERB
admet-510	19	7	of	of	ADP
admet-510	19	8	two	two	NUM
admet-510	19	9	main	main	ADJ
admet-510	19	10	phases	phase	NOUN
admet-510	19	11	,	,	PUNCT
admet-510	19	12	an	an	DET
admet-510	19	13	aqueous	aqueous	ADJ
admet-510	19	14	phase	phase	NOUN
admet-510	19	15	(	(	PUNCT
admet-510	19	16	buffer	buffer	NOUN
admet-510	19	17	)	)	PUNCT
admet-510	19	18	and	and	CCONJ
admet-510	19	19	a	a	DET
admet-510	19	20	pseudostationary	pseudostationary	ADJ
admet-510	19	21	phase	phase	NOUN
admet-510	19	22	(	(	PUNCT
admet-510	19	23	the	the	DET
admet-510	19	24	microemulsion	microemulsion	NOUN
admet-510	19	25	)	)	PUNCT
admet-510	19	26	.	.	PUNCT
admet-510	20	1	further	further	ADJ
admet-510	20	2	studies	study	NOUN
admet-510	20	3	[	[	X
admet-510	20	4	2,3	2,3	NUM
admet-510	20	5	]	]	PUNCT
admet-510	20	6	followed	follow	VERB
admet-510	20	7	the	the	DET
admet-510	20	8	method	method	NOUN
admet-510	20	9	and	and	CCONJ
admet-510	20	10	correlated	correlate	VERB
admet-510	20	11	satisfactorily	satisfactorily	ADV
admet-510	20	12	the	the	DET
admet-510	20	13	logarithm	logarithm	NOUN
admet-510	20	14	of	of	ADP
admet-510	20	15	the	the	DET
admet-510	20	16	octanolwater	octanolwater	NOUN
admet-510	20	17	partition	partition	NOUN
admet-510	20	18	coefficient	coefficient	NOUN
admet-510	20	19	(	(	PUNCT
admet-510	20	20	log	log	VERB
admet-510	20	21	po	po	PROPN
admet-510	20	22	/	/	SYM
admet-510	20	23	w	w	PROPN
admet-510	20	24	)	)	PUNCT
admet-510	20	25	to	to	ADP
admet-510	20	26	the	the	DET
admet-510	20	27	logarithm	logarithm	NOUN
admet-510	20	28	of	of	ADP
admet-510	20	29	the	the	DET
admet-510	20	30	retention	retention	NOUN
admet-510	20	31	factor	factor	NOUN
admet-510	20	32	in	in	ADP
admet-510	20	33	meekc	meekc	PROPN
admet-510	20	34	(	(	PUNCT
admet-510	20	35	log	log	PROPN
admet-510	20	36	kmeekc	kmeekc	PROPN
admet-510	20	37	)	)	PUNCT
admet-510	20	38	.	.	PUNCT
admet-510	21	1	abraham	abraham	PROPN
admet-510	21	2	et	et	PROPN
admet-510	21	3	al	al	PROPN
admet-510	21	4	.	.	PUNCT
admet-510	22	1	[	[	X
admet-510	22	2	2	2	X
admet-510	22	3	]	]	PUNCT
admet-510	22	4	correlated	correlate	VERB
admet-510	22	5	log	log	NOUN
admet-510	22	6	po	po	PROPN
admet-510	22	7	/	/	SYM
admet-510	22	8	w	w	NOUN
admet-510	22	9	to	to	PART
admet-510	22	10	log	log	VERB
admet-510	22	11	kmeekc	kmeekc	PROPN
admet-510	22	12	measured	measure	VERB
admet-510	22	13	in	in	ADP
admet-510	22	14	a	a	DET
admet-510	22	15	system	system	NOUN
admet-510	22	16	with	with	ADP
admet-510	22	17	a	a	DET
admet-510	22	18	microemulsion	microemulsion	NOUN
admet-510	22	19	composed	compose	VERB
admet-510	22	20	of	of	ADP
admet-510	22	21	1.44	1.44	NUM
admet-510	22	22	%	%	NOUN
admet-510	22	23	(	(	PUNCT
admet-510	22	24	w	w	NOUN
admet-510	22	25	/	/	SYM
admet-510	22	26	w	w	PROPN
admet-510	22	27	)	)	PUNCT
admet-510	22	28	sds	sds	NOUN
admet-510	22	29	,	,	PUNCT
admet-510	22	30	6.49	6.49	NUM
admet-510	22	31	%	%	NOUN
admet-510	22	32	(	(	PUNCT
admet-510	22	33	w	w	NOUN
admet-510	22	34	/	/	SYM
admet-510	22	35	w	w	NOUN
admet-510	22	36	)	)	PUNCT
admet-510	22	37	1	1	NUM
admet-510	22	38	-	-	PUNCT
admet-510	22	39	butanol	butanol	NOUN
admet-510	22	40	,	,	PUNCT
admet-510	22	41	and	and	CCONJ
admet-510	22	42	0.82	0.82	NUM
admet-510	22	43	%	%	NOUN
admet-510	22	44	(	(	PUNCT
admet-510	22	45	w	w	NOUN
admet-510	22	46	/	/	SYM
admet-510	22	47	w	w	NOUN
admet-510	22	48	)	)	PUNCT
admet-510	22	49	heptane	heptane	NOUN
admet-510	22	50	,	,	PUNCT
admet-510	22	51	obtaining	obtain	VERB
admet-510	22	52	the	the	DET
admet-510	22	53	following	follow	VERB
admet-510	22	54	equation	equation	NOUN
admet-510	22	55	:	:	PUNCT
admet-510	22	56	log	log	VERB
admet-510	22	57	po	po	NOUN
admet-510	22	58	/	/	SYM
admet-510	22	59	w=	w=	NOUN
admet-510	22	60	1.542	1.542	NUM
admet-510	22	61	+	+	NUM
admet-510	22	62	1.276·log	1.276·log	NUM
admet-510	22	63	kmeekc	kmeekc	NOUN
admet-510	22	64	,	,	PUNCT
admet-510	22	65	r	r	NOUN
admet-510	22	66	2=0.99	2=0.99	NUM
admet-510	22	67	;	;	PUNCT
admet-510	22	68	sd=0.096	sd=0.096	NOUN
admet-510	22	69	;	;	PUNCT
admet-510	22	70	n=53	n=53	ADV
admet-510	22	71	.	.	PUNCT
admet-510	23	1	(	(	PUNCT
admet-510	23	2	1	1	X
admet-510	23	3	)	)	PUNCT
admet-510	23	4	subirats	subirat	NOUN
admet-510	23	5	et	et	NOUN
admet-510	23	6	al	al	PROPN
admet-510	23	7	.	.	PUNCT
admet-510	24	1	[	[	X
admet-510	24	2	3	3	NUM
admet-510	24	3	]	]	PUNCT
admet-510	24	4	performed	perform	VERB
admet-510	24	5	the	the	DET
admet-510	24	6	same	same	ADJ
admet-510	24	7	procedure	procedure	NOUN
admet-510	24	8	using	use	VERB
admet-510	24	9	a	a	DET
admet-510	24	10	microemulsion	microemulsion	NOUN
admet-510	24	11	consisting	consist	VERB
admet-510	24	12	of	of	ADP
admet-510	24	13	1.3	1.3	NUM
admet-510	24	14	%	%	NOUN
admet-510	24	15	(	(	PUNCT
admet-510	24	16	w	w	NOUN
admet-510	24	17	/	/	SYM
admet-510	24	18	v	v	NOUN
admet-510	24	19	)	)	PUNCT
admet-510	24	20	sds	sds	NOUN
admet-510	24	21	,	,	PUNCT
admet-510	24	22	8.15	8.15	NUM
admet-510	24	23	%	%	NOUN
admet-510	24	24	(	(	PUNCT
admet-510	24	25	v	v	NOUN
admet-510	24	26	/	/	SYM
admet-510	24	27	v	v	NOUN
admet-510	24	28	)	)	PUNCT
admet-510	24	29	1	1	NUM
admet-510	24	30	-	-	PUNCT
admet-510	24	31	butanol	butanol	NOUN
admet-510	24	32	,	,	PUNCT
admet-510	24	33	1.15	1.15	NUM
admet-510	24	34	%	%	NOUN
admet-510	24	35	(	(	PUNCT
admet-510	24	36	v	v	NOUN
admet-510	24	37	/	/	SYM
admet-510	24	38	v	v	NOUN
admet-510	24	39	)	)	PUNCT
admet-510	24	40	heptane	heptane	NOUN
admet-510	24	41	,	,	PUNCT
admet-510	24	42	and	and	CCONJ
admet-510	24	43	5	5	NUM
admet-510	24	44	%	%	NOUN
admet-510	24	45	(	(	PUNCT
admet-510	24	46	v	v	NOUN
admet-510	24	47	/	/	SYM
admet-510	24	48	v	v	NOUN
admet-510	24	49	)	)	PUNCT
admet-510	24	50	acetonitrile	acetonitrile	NOUN
admet-510	24	51	(	(	PUNCT
admet-510	24	52	at	at	ADP
admet-510	24	53	ph	ph	NOUN
admet-510	24	54	7.4	7.4	NUM
admet-510	24	55	,	,	PUNCT
admet-510	24	56	in	in	ADP
admet-510	24	57	a	a	DET
admet-510	24	58	10	10	NUM
admet-510	24	59	mm	mm	NOUN
admet-510	24	60	phosphate	phosphate	NOUN
admet-510	24	61	buffer	buffer	NOUN
admet-510	24	62	)	)	PUNCT
admet-510	24	63	.	.	PUNCT
admet-510	25	1	acetonitrile	acetonitrile	NOUN
admet-510	25	2	was	be	AUX
admet-510	25	3	added	add	VERB
admet-510	25	4	to	to	PART
admet-510	25	5	overcome	overcome	VERB
admet-510	25	6	the	the	DET
admet-510	25	7	co	co	NOUN
admet-510	25	8	-	-	NOUN
admet-510	25	9	elution	elution	NOUN
admet-510	25	10	of	of	ADP
admet-510	25	11	the	the	DET
admet-510	25	12	microemulsion	microemulsion	NOUN
admet-510	25	13	marker	marker	NOUN
admet-510	25	14	with	with	ADP
admet-510	25	15	the	the	DET
admet-510	25	16	most	most	ADV
admet-510	25	17	lipophilic	lipophilic	ADJ
admet-510	25	18	compounds	compound	NOUN
admet-510	25	19	.	.	PUNCT
admet-510	26	1	the	the	DET
admet-510	26	2	resulting	result	VERB
admet-510	26	3	equation	equation	NOUN
admet-510	26	4	of	of	ADP
admet-510	26	5	the	the	DET
admet-510	26	6	correlation	correlation	NOUN
admet-510	26	7	and	and	CCONJ
admet-510	26	8	the	the	DET
admet-510	26	9	statistics	statistic	NOUN
admet-510	26	10	are	be	AUX
admet-510	26	11	:	:	PUNCT
admet-510	26	12	log	log	VERB
admet-510	26	13	po	po	NOUN
admet-510	26	14	/	/	SYM
admet-510	26	15	w=	w=	PROPN
admet-510	26	16	1.48	1.48	NUM
admet-510	26	17	(	(	PUNCT
admet-510	26	18	±0.05	±0.05	PROPN
admet-510	26	19	)	)	PUNCT
admet-510	26	20	+	+	NUM
admet-510	27	1	1.48	1.48	NUM
admet-510	27	2	(	(	PUNCT
admet-510	27	3	±0.05)·log	±0.05)·log	PROPN
admet-510	27	4	kmeekc	kmeekc	PROPN
admet-510	27	5	,	,	PUNCT
admet-510	27	6	r2=0.96	r2=0.96	PROPN
admet-510	27	7	;	;	PUNCT
admet-510	27	8	n=32	n=32	X
admet-510	27	9	.	.	PUNCT
admet-510	28	1	(	(	PUNCT
admet-510	28	2	2	2	X
admet-510	28	3	)	)	PUNCT
admet-510	28	4	taking	take	VERB
admet-510	28	5	into	into	ADP
admet-510	28	6	account	account	NOUN
admet-510	28	7	equations	equation	NOUN
admet-510	28	8	1	1	NUM
admet-510	28	9	and	and	CCONJ
admet-510	28	10	2	2	NUM
admet-510	28	11	it	it	PRON
admet-510	28	12	can	can	AUX
admet-510	28	13	be	be	AUX
admet-510	28	14	concluded	conclude	VERB
admet-510	28	15	that	that	SCONJ
admet-510	28	16	this	this	DET
admet-510	28	17	method	method	NOUN
admet-510	28	18	is	be	AUX
admet-510	28	19	able	able	ADJ
admet-510	28	20	to	to	PART
admet-510	28	21	predict	predict	VERB
admet-510	28	22	the	the	DET
admet-510	28	23	octanol	octanol	NOUN
admet-510	28	24	-	-	PUNCT
admet-510	28	25	water	water	NOUN
admet-510	28	26	partition	partition	NOUN
admet-510	28	27	coefficient	coefficient	NOUN
admet-510	28	28	of	of	ADP
admet-510	28	29	new	new	ADJ
admet-510	28	30	compounds	compound	NOUN
admet-510	28	31	in	in	ADP
admet-510	28	32	their	their	PRON
admet-510	28	33	neutral	neutral	ADJ
admet-510	28	34	form	form	NOUN
admet-510	28	35	through	through	ADP
admet-510	28	36	electrokinetic	electrokinetic	ADJ
admet-510	28	37	measurements	measurement	NOUN
admet-510	28	38	.	.	PUNCT
admet-510	29	1	considering	consider	VERB
admet-510	29	2	that	that	SCONJ
admet-510	29	3	most	most	ADJ
admet-510	29	4	part	part	NOUN
admet-510	29	5	of	of	ADP
admet-510	29	6	pharmaceutical	pharmaceutical	ADJ
admet-510	29	7	drugs	drug	NOUN
admet-510	29	8	are	be	AUX
admet-510	29	9	acids	acid	NOUN
admet-510	29	10	or	or	CCONJ
admet-510	29	11	bases	basis	NOUN
admet-510	29	12	,	,	PUNCT
admet-510	29	13	a	a	DET
admet-510	29	14	fast	fast	ADJ
admet-510	29	15	determination	determination	NOUN
admet-510	29	16	of	of	ADP
admet-510	29	17	this	this	DET
admet-510	29	18	parameter	parameter	NOUN
admet-510	29	19	for	for	ADP
admet-510	29	20	ionic	ionic	ADJ
admet-510	29	21	compounds	compound	NOUN
admet-510	29	22	is	be	AUX
admet-510	29	23	of	of	ADP
admet-510	29	24	great	great	ADJ
admet-510	29	25	interest	interest	NOUN
admet-510	29	26	.	.	PUNCT
admet-510	30	1	therefore	therefore	ADV
admet-510	30	2	,	,	PUNCT
admet-510	30	3	the	the	DET
admet-510	30	4	aim	aim	NOUN
admet-510	30	5	of	of	ADP
admet-510	30	6	this	this	DET
admet-510	30	7	work	work	NOUN
admet-510	30	8	is	be	AUX
admet-510	30	9	to	to	PART
admet-510	30	10	test	test	VERB
admet-510	30	11	the	the	DET
admet-510	30	12	applicability	applicability	NOUN
admet-510	30	13	of	of	ADP
admet-510	30	14	meekc	meekc	ADJ
admet-510	30	15	measurements	measurement	NOUN
admet-510	30	16	to	to	PART
admet-510	30	17	estimate	estimate	VERB
admet-510	30	18	the	the	DET
admet-510	30	19	logarithm	logarithm	NOUN
admet-510	30	20	of	of	ADP
admet-510	30	21	the	the	DET
admet-510	30	22	octanol	octanol	NOUN
admet-510	30	23	-	-	PUNCT
admet-510	30	24	water	water	NOUN
admet-510	30	25	distribution	distribution	NOUN
admet-510	30	26	coefficient	coefficient	NOUN
admet-510	30	27	(	(	PUNCT
admet-510	30	28	log	log	NOUN
admet-510	30	29	do	do	AUX
admet-510	30	30	/	/	SYM
admet-510	30	31	w	w	NOUN
admet-510	30	32	)	)	PUNCT
admet-510	30	33	of	of	ADP
admet-510	30	34	acidic	acidic	ADJ
admet-510	30	35	solutes	solute	NOUN
admet-510	30	36	at	at	ADP
admet-510	30	37	several	several	ADJ
admet-510	30	38	degrees	degree	NOUN
admet-510	30	39	of	of	ADP
admet-510	30	40	ionization	ionization	NOUN
admet-510	30	41	.	.	PUNCT
admet-510	31	1	naproxen	naproxen	NOUN
admet-510	31	2	has	have	AUX
admet-510	31	3	been	be	AUX
admet-510	31	4	employed	employ	VERB
admet-510	31	5	as	as	ADP
admet-510	31	6	test	test	NOUN
admet-510	31	7	solute	solute	NOUN
admet-510	31	8	since	since	SCONJ
admet-510	31	9	it	it	PRON
admet-510	31	10	is	be	AUX
admet-510	31	11	an	an	DET
admet-510	31	12	acid	acid	NOUN
admet-510	31	13	that	that	PRON
admet-510	31	14	presents	present	VERB
admet-510	31	15	a	a	DET
admet-510	31	16	pka	pka	NOUN
admet-510	31	17	close	close	ADV
admet-510	31	18	to	to	ADP
admet-510	31	19	4	4	NUM
admet-510	31	20	(	(	PUNCT
admet-510	31	21	within	within	ADP
admet-510	31	22	the	the	DET
admet-510	31	23	electrophoretic	electrophoretic	ADJ
admet-510	31	24	working	work	VERB
admet-510	31	25	ph	ph	ADJ
admet-510	31	26	range	range	NOUN
admet-510	31	27	)	)	PUNCT
admet-510	31	28	,	,	PUNCT
admet-510	31	29	its	its	PRON
admet-510	31	30	lipophilicity	lipophilicity	NOUN
admet-510	31	31	-	-	PUNCT
admet-510	31	32	ph	ph	NOUN
admet-510	31	33	profile	profile	NOUN
admet-510	31	34	is	be	AUX
admet-510	31	35	well	well	ADV
admet-510	31	36	-	-	PUNCT
admet-510	31	37	defined	define	VERB
admet-510	31	38	in	in	ADP
admet-510	31	39	the	the	DET
admet-510	31	40	literature	literature	NOUN
admet-510	31	41	[	[	X
admet-510	31	42	4,5	4,5	NUM
admet-510	31	43	]	]	PUNCT
admet-510	31	44	,	,	PUNCT
admet-510	31	45	and	and	CCONJ
admet-510	31	46	it	it	PRON
admet-510	31	47	contains	contain	VERB
admet-510	31	48	chromophore	chromophore	NOUN
admet-510	31	49	groups	group	NOUN
admet-510	31	50	(	(	PUNCT
admet-510	31	51	therefore	therefore	ADV
admet-510	31	52	detectable	detectable	ADJ
admet-510	31	53	by	by	ADP
admet-510	31	54	uv	uv	NOUN
admet-510	31	55	-	-	PUNCT
admet-510	31	56	vis	vis	X
admet-510	31	57	)	)	PUNCT
admet-510	31	58	.	.	PUNCT
admet-510	32	1	experimental	experimental	ADJ
admet-510	32	2	a	a	DET
admet-510	32	3	capillary	capillary	ADJ
admet-510	32	4	electrophoresis	electrophoresis	NOUN
admet-510	32	5	system	system	NOUN
admet-510	32	6	(	(	PUNCT
admet-510	32	7	ce	ce	PROPN
admet-510	32	8	7100	7100	NUM
admet-510	32	9	)	)	PUNCT
admet-510	32	10	equipped	equip	VERB
admet-510	32	11	with	with	ADP
admet-510	32	12	a	a	DET
admet-510	32	13	diode	diode	NOUN
admet-510	32	14	array	array	NOUN
admet-510	32	15	from	from	ADP
admet-510	32	16	agilent	agilent	PROPN
admet-510	32	17	technologies	technology	NOUN
admet-510	32	18	(	(	PUNCT
admet-510	32	19	santa	santa	PROPN
admet-510	32	20	clara	clara	PROPN
admet-510	32	21	,	,	PUNCT
admet-510	32	22	ca	ca	PROPN
admet-510	32	23	,	,	PUNCT
admet-510	32	24	usa	usa	PROPN
admet-510	32	25	)	)	PUNCT
admet-510	32	26	was	be	AUX
admet-510	32	27	employed	employ	VERB
admet-510	32	28	to	to	PART
admet-510	32	29	do	do	VERB
admet-510	32	30	the	the	DET
admet-510	32	31	electrophoretic	electrophoretic	ADJ
admet-510	32	32	measurements	measurement	NOUN
admet-510	32	33	.	.	PUNCT
admet-510	33	1	the	the	DET
admet-510	33	2	fused	fuse	VERB
admet-510	33	3	-	-	PUNCT
admet-510	33	4	silica	silica	NOUN
admet-510	33	5	capillary	capillary	ADJ
admet-510	33	6	used	use	VERB
admet-510	33	7	was	be	AUX
admet-510	33	8	from	from	ADP
admet-510	33	9	polymicro	polymicro	ADJ
admet-510	33	10	technologies	technology	NOUN
admet-510	33	11	(	(	PUNCT
admet-510	33	12	lisle	lisle	PROPN
admet-510	33	13	,	,	PUNCT
admet-510	33	14	il	il	PROPN
admet-510	33	15	,	,	PUNCT
admet-510	33	16	usa	usa	PROPN
admet-510	33	17	)	)	PUNCT
admet-510	33	18	with	with	ADP
admet-510	33	19	an	an	DET
admet-510	33	20	effective	effective	ADJ
admet-510	33	21	length	length	NOUN
admet-510	33	22	of	of	ADP
admet-510	33	23	25	25	NUM
admet-510	33	24	or	or	CCONJ
admet-510	33	25	30	30	NUM
admet-510	33	26	cm	cm	NOUN
admet-510	33	27	(	(	PUNCT
admet-510	33	28	depending	depend	VERB
admet-510	33	29	on	on	ADP
admet-510	33	30	the	the	DET
admet-510	33	31	ph	ph	ADJ
admet-510	33	32	value	value	NOUN
admet-510	33	33	)	)	PUNCT
admet-510	33	34	and	and	CCONJ
admet-510	33	35	an	an	DET
admet-510	33	36	internal	internal	ADJ
admet-510	33	37	diameter	diameter	NOUN
admet-510	33	38	of	of	ADP
admet-510	33	39	50	50	NUM
admet-510	33	40	μm	μm	NOUN
admet-510	33	41	.	.	PUNCT
admet-510	34	1	the	the	DET
admet-510	34	2	microemulsion	microemulsion	NOUN
admet-510	34	3	used	use	VERB
admet-510	34	4	as	as	ADP
admet-510	34	5	the	the	DET
admet-510	34	6	pseudostationary	pseudostationary	ADJ
admet-510	34	7	phase	phase	NOUN
admet-510	34	8	was	be	AUX
admet-510	34	9	prepared	prepare	VERB
admet-510	34	10	in	in	ADP
admet-510	34	11	a	a	DET
admet-510	34	12	phosphate	phosphate	ADJ
admet-510	34	13	or	or	CCONJ
admet-510	34	14	acetate	acetate	NOUN
admet-510	34	15	buffer	buffer	NOUN
admet-510	34	16	at	at	ADP
admet-510	34	17	0.05	0.05	NUM
admet-510	34	18	m	m	NOUN
admet-510	34	19	ionic	ionic	ADJ
admet-510	34	20	strength	strength	NOUN
admet-510	34	21	.	.	PUNCT
admet-510	35	1	first	first	ADV
admet-510	35	2	,	,	PUNCT
admet-510	35	3	the	the	DET
admet-510	35	4	surfactant	surfactant	NOUN
admet-510	35	5	(	(	PUNCT
admet-510	35	6	sds	sds	PROPN
admet-510	35	7	)	)	PUNCT
admet-510	35	8	was	be	AUX
admet-510	35	9	dissolved	dissolve	VERB
admet-510	35	10	in	in	ADP
admet-510	35	11	the	the	DET
admet-510	35	12	buffer	buffer	NOUN
admet-510	35	13	at	at	ADP
admet-510	35	14	1.30	1.30	NUM
admet-510	35	15	%	%	NOUN
admet-510	35	16	(	(	PUNCT
admet-510	35	17	w	w	NOUN
admet-510	35	18	/	/	SYM
admet-510	35	19	v	v	NOUN
admet-510	35	20	)	)	PUNCT
admet-510	35	21	,	,	PUNCT
admet-510	35	22	then	then	ADV
admet-510	35	23	the	the	DET
admet-510	35	24	co	co	NOUN
admet-510	35	25	-	-	NOUN
admet-510	35	26	surfactant	surfactant	ADJ
admet-510	35	27	(	(	PUNCT
admet-510	35	28	1	1	NUM
admet-510	35	29	-	-	PUNCT
admet-510	35	30	butanol	butanol	NOUN
admet-510	35	31	)	)	PUNCT
admet-510	35	32	was	be	AUX
admet-510	35	33	added	add	VERB
admet-510	35	34	at	at	ADP
admet-510	35	35	8.15	8.15	NUM
admet-510	35	36	%	%	NOUN
admet-510	35	37	(	(	PUNCT
admet-510	35	38	v	v	NOUN
admet-510	35	39	/	/	SYM
admet-510	35	40	v	v	NOUN
admet-510	35	41	)	)	PUNCT
admet-510	35	42	,	,	PUNCT
admet-510	35	43	followed	follow	VERB
admet-510	35	44	by	by	ADP
admet-510	35	45	the	the	DET
admet-510	35	46	addition	addition	NOUN
admet-510	35	47	of	of	ADP
admet-510	35	48	the	the	DET
admet-510	35	49	oil	oil	NOUN
admet-510	35	50	(	(	PUNCT
admet-510	35	51	heptane	heptane	NOUN
admet-510	35	52	)	)	PUNCT
admet-510	35	53	at	at	ADP
admet-510	35	54	1.15	1.15	NUM
admet-510	35	55	%	%	NOUN
admet-510	35	56	(	(	PUNCT
admet-510	35	57	v	v	NOUN
admet-510	35	58	/	/	SYM
admet-510	35	59	v	v	NOUN
admet-510	35	60	)	)	PUNCT
admet-510	35	61	.	.	PUNCT
admet-510	36	1	the	the	DET
admet-510	36	2	solution	solution	NOUN
admet-510	36	3	was	be	AUX
admet-510	36	4	stirred	stir	VERB
admet-510	36	5	and	and	CCONJ
admet-510	36	6	sonicated	sonicate	VERB
admet-510	36	7	until	until	SCONJ
admet-510	36	8	the	the	DET
admet-510	36	9	turbidity	turbidity	NOUN
admet-510	36	10	was	be	AUX
admet-510	36	11	no	no	ADV
admet-510	36	12	longer	long	ADV
admet-510	36	13	observed	observe	VERB
admet-510	36	14	[	[	X
admet-510	36	15	3	3	NUM
admet-510	36	16	]	]	PUNCT
admet-510	36	17	.	.	PUNCT
admet-510	37	1	the	the	DET
admet-510	37	2	analyses	analysis	NOUN
admet-510	37	3	were	be	AUX
admet-510	37	4	performed	perform	VERB
admet-510	37	5	using	use	VERB
admet-510	37	6	two	two	NUM
admet-510	37	7	different	different	ADJ
admet-510	37	8	solutions	solution	NOUN
admet-510	37	9	(	(	PUNCT
admet-510	37	10	in	in	ADP
admet-510	37	11	the	the	DET
admet-510	37	12	microemulsion	microemulsion	NOUN
admet-510	37	13	and	and	CCONJ
admet-510	37	14	in	in	ADP
admet-510	37	15	a	a	DET
admet-510	37	16	buffer	buffer	NOUN
admet-510	37	17	without	without	ADP
admet-510	37	18	the	the	DET
admet-510	37	19	pseudostationary	pseudostationary	ADJ
admet-510	37	20	phase	phase	NOUN
admet-510	37	21	)	)	PUNCT
admet-510	37	22	at	at	ADP
admet-510	37	23	25	25	NUM
admet-510	37	24	°	°	NOUN
admet-510	37	25	c	c	NOUN
admet-510	37	26	,	,	PUNCT
admet-510	37	27	applying	apply	VERB
admet-510	37	28	a	a	DET
admet-510	37	29	voltage	voltage	NOUN
admet-510	37	30	ranging	range	VERB
admet-510	37	31	from	from	ADP
admet-510	37	32	8	8	NUM
admet-510	37	33	to	to	ADP
admet-510	37	34	15	15	NUM
admet-510	37	35	kv	kv	PROPN
admet-510	37	36	,	,	PUNCT
admet-510	37	37	and	and	CCONJ
admet-510	37	38	an	an	DET
admet-510	37	39	internal	internal	ADJ
admet-510	37	40	pressure	pressure	NOUN
admet-510	37	41	ranging	range	VERB
admet-510	37	42	from	from	ADP
admet-510	37	43	0	0	NUM
admet-510	37	44	to	to	ADP
admet-510	37	45	50	50	NUM
admet-510	37	46	mbar	mbar	NOUN
admet-510	37	47	(	(	PUNCT
admet-510	37	48	depending	depend	VERB
admet-510	37	49	on	on	ADP
admet-510	37	50	the	the	DET
admet-510	37	51	buffer	buffer	NOUN
admet-510	37	52	and	and	CCONJ
admet-510	37	53	the	the	DET
admet-510	37	54	ph	ph	NOUN
admet-510	37	55	of	of	ADP
admet-510	37	56	each	each	DET
admet-510	37	57	experiment	experiment	NOUN
admet-510	37	58	)	)	PUNCT
admet-510	37	59	.	.	PUNCT
admet-510	38	1	the	the	DET
admet-510	38	2	solutes	solute	NOUN
admet-510	38	3	were	be	AUX
admet-510	38	4	injected	inject	VERB
admet-510	38	5	with	with	ADP
admet-510	38	6	a	a	DET
admet-510	38	7	pressure	pressure	NOUN
admet-510	38	8	of	of	ADP
admet-510	38	9	50	50	NUM
admet-510	38	10	mbar	mbar	NOUN
admet-510	38	11	during	during	ADP
admet-510	38	12	5	5	NUM
admet-510	38	13	s.	s.	PROPN
admet-510	38	14	dodecanophenone	dodecanophenone	PROPN
admet-510	38	15	was	be	AUX
admet-510	38	16	employed	employ	VERB
admet-510	38	17	as	as	ADP
admet-510	38	18	the	the	DET
admet-510	38	19	microemulsion	microemulsion	NOUN
admet-510	38	20	marker	marker	NOUN
admet-510	38	21	and	and	CCONJ
admet-510	38	22	dmso	dmso	NOUN
admet-510	38	23	as	as	ADP
admet-510	38	24	the	the	DET
admet-510	38	25	electroosmotic	electroosmotic	ADJ
admet-510	38	26	flow	flow	NOUN
admet-510	38	27	marker	marker	NOUN
admet-510	38	28	.	.	PUNCT
admet-510	39	1	the	the	DET
admet-510	39	2	solute	solute	NOUN
admet-510	39	3	to	to	PART
admet-510	39	4	be	be	AUX
admet-510	39	5	injected	inject	VERB
admet-510	39	6	was	be	AUX
admet-510	39	7	disolved	disolve	VERB
admet-510	39	8	in	in	ADP
admet-510	39	9	microemulsion	microemulsion	NOUN
admet-510	39	10	/	/	SYM
admet-510	39	11	methanol	methanol	NOUN
admet-510	39	12	mixture	mixture	NOUN
admet-510	39	13	at	at	ADP
admet-510	39	14	9:1	9:1	NUM
admet-510	39	15	ratio	ratio	NOUN
admet-510	39	16	,	,	PUNCT
admet-510	39	17	in	in	ADP
admet-510	39	18	meekc	meekc	ADJ
admet-510	39	19	measurements	measurement	NOUN
admet-510	39	20	,	,	PUNCT
admet-510	39	21	and	and	CCONJ
admet-510	39	22	in	in	ADP
admet-510	39	23	water	water	NOUN
admet-510	39	24	/	/	SYM
admet-510	39	25	methanol	methanol	NOUN
admet-510	39	26	mixture	mixture	NOUN
admet-510	39	27	at	at	ADP
admet-510	39	28	9:1	9:1	NUM
admet-510	39	29	ratio	ratio	NOUN
admet-510	39	30	,	,	PUNCT
admet-510	39	31	in	in	ADP
admet-510	39	32	plain	plain	ADJ
admet-510	39	33	buffer	buffer	NOUN
admet-510	39	34	measurements	measurement	NOUN
admet-510	39	35	,	,	PUNCT
admet-510	39	36	with	with	ADP
admet-510	39	37	a	a	DET
admet-510	39	38	final	final	ADJ
admet-510	39	39	concentration	concentration	NOUN
admet-510	39	40	of	of	ADP
admet-510	39	41	approximately	approximately	ADV
admet-510	39	42	200	200	NUM
admet-510	39	43	mg	mg	PROPN
admet-510	39	44	/	/	SYM
admet-510	39	45	l.	l.	PROPN
admet-510	39	46	admet	admet	PROPN
admet-510	39	47	&	&	CCONJ
admet-510	39	48	dmpk	dmpk	PROPN
admet-510	39	49	6(1	6(1	NUM
admet-510	39	50	)	)	PUNCT
admet-510	39	51	(	(	PUNCT
admet-510	39	52	2018	2018	NUM
admet-510	39	53	)	)	PUNCT
admet-510	39	54	55	55	NUM
admet-510	39	55	-	-	SYM
admet-510	39	56	60	60	NUM
admet-510	39	57	estimation	estimation	NOUN
admet-510	39	58	of	of	ADP
admet-510	39	59	octanol	octanol	NOUN
admet-510	39	60	-	-	PUNCT
admet-510	39	61	water	water	NOUN
admet-510	39	62	log	log	NOUN
admet-510	39	63	do	do	AUX
admet-510	39	64	/	/	SYM
admet-510	39	65	w	w	NOUN
admet-510	39	66	of	of	ADP
admet-510	39	67	acidic	acidic	ADJ
admet-510	39	68	drugs	drug	NOUN
admet-510	39	69	by	by	ADP
admet-510	39	70	meekc	meekc	ADJ
admet-510	39	71	doi	doi	PROPN
admet-510	39	72	:	:	PUNCT
admet-510	39	73	10.5599	10.5599	NUM
admet-510	39	74	/	/	SYM
admet-510	39	75	admet.6.1.510	admet.6.1.510	NUM
admet-510	39	76	57	57	NUM
admet-510	39	77	theory	theory	NOUN
admet-510	39	78	the	the	DET
admet-510	39	79	migration	migration	NOUN
admet-510	39	80	behavior	behavior	NOUN
admet-510	39	81	of	of	ADP
admet-510	39	82	an	an	DET
admet-510	39	83	acidic	acidic	ADJ
admet-510	39	84	compound	compound	NOUN
admet-510	39	85	when	when	SCONJ
admet-510	39	86	it	it	PRON
admet-510	39	87	is	be	AUX
admet-510	39	88	partially	partially	ADV
admet-510	39	89	or	or	CCONJ
admet-510	39	90	totally	totally	ADV
admet-510	39	91	ionized	ionized	ADJ
admet-510	39	92	is	be	AUX
admet-510	39	93	a	a	DET
admet-510	39	94	contribution	contribution	NOUN
admet-510	39	95	of	of	ADP
admet-510	39	96	two	two	NUM
admet-510	39	97	main	main	ADJ
admet-510	39	98	factors	factor	NOUN
admet-510	40	1	[	[	X
admet-510	40	2	6	6	NUM
admet-510	40	3	]	]	PUNCT
admet-510	40	4	:	:	PUNCT
admet-510	40	5	the	the	DET
admet-510	40	6	hydrophobic	hydrophobic	NOUN
admet-510	40	7	interaction	interaction	NOUN
admet-510	40	8	of	of	ADP
admet-510	40	9	the	the	DET
admet-510	40	10	compound	compound	NOUN
admet-510	40	11	with	with	ADP
admet-510	40	12	the	the	DET
admet-510	40	13	pseudostationary	pseudostationary	ADJ
admet-510	40	14	phase	phase	NOUN
admet-510	40	15	(	(	PUNCT
admet-510	40	16	the	the	DET
admet-510	40	17	microemulsion	microemulsion	NOUN
admet-510	40	18	)	)	PUNCT
admet-510	40	19	,	,	PUNCT
admet-510	40	20	and	and	CCONJ
admet-510	40	21	the	the	DET
admet-510	40	22	electrophoretic	electrophoretic	ADJ
admet-510	40	23	mobility	mobility	NOUN
admet-510	40	24	of	of	ADP
admet-510	40	25	the	the	DET
admet-510	40	26	anionic	anionic	ADJ
admet-510	40	27	acid	acid	NOUN
admet-510	40	28	by	by	ADP
admet-510	40	29	its	its	PRON
admet-510	40	30	electrostatic	electrostatic	ADJ
admet-510	40	31	attraction	attraction	NOUN
admet-510	40	32	to	to	ADP
admet-510	40	33	the	the	DET
admet-510	40	34	anode	anode	NOUN
admet-510	40	35	(	(	PUNCT
admet-510	40	36	with	with	ADP
admet-510	40	37	positive	positive	ADJ
admet-510	40	38	charge	charge	NOUN
admet-510	40	39	)	)	PUNCT
admet-510	40	40	.	.	PUNCT
admet-510	41	1	retention	retention	NOUN
admet-510	41	2	factor	factor	NOUN
admet-510	41	3	of	of	ADP
admet-510	41	4	ionized	ionized	ADJ
admet-510	41	5	compounds	compound	NOUN
admet-510	41	6	can	can	AUX
admet-510	41	7	be	be	AUX
admet-510	41	8	calculated	calculate	VERB
admet-510	41	9	through	through	ADP
admet-510	41	10	the	the	DET
admet-510	41	11	next	next	ADJ
admet-510	41	12	equation	equation	NOUN
admet-510	41	13	:	:	PUNCT
admet-510	41	14	𝑘	𝑘	PROPN
admet-510	41	15	=	=	PUNCT
admet-510	41	16	𝜇−𝜇0	𝜇−𝜇0	X
admet-510	41	17	𝜇me−𝜇	𝜇me−𝜇	PROPN
admet-510	41	18	,	,	PUNCT
admet-510	41	19	(	(	PUNCT
admet-510	41	20	3	3	X
admet-510	41	21	)	)	PUNCT
admet-510	41	22	where	where	SCONJ
admet-510	41	23	,	,	PUNCT
admet-510	41	24	k	k	PROPN
admet-510	41	25	is	be	AUX
admet-510	41	26	the	the	DET
admet-510	41	27	retention	retention	NOUN
admet-510	41	28	factor	factor	NOUN
admet-510	41	29	of	of	ADP
admet-510	41	30	the	the	DET
admet-510	41	31	solute	solute	NOUN
admet-510	41	32	,	,	PUNCT
admet-510	41	33	µ	µ	VERB
admet-510	41	34	the	the	DET
admet-510	41	35	overall	overall	ADJ
admet-510	41	36	observed	observed	ADJ
admet-510	41	37	mobility	mobility	NOUN
admet-510	41	38	of	of	ADP
admet-510	41	39	the	the	DET
admet-510	41	40	compound	compound	NOUN
admet-510	41	41	,	,	PUNCT
admet-510	41	42	µme	µme	VERB
admet-510	41	43	the	the	DET
admet-510	41	44	mobility	mobility	NOUN
admet-510	41	45	of	of	ADP
admet-510	41	46	the	the	DET
admet-510	41	47	microemulsion	microemulsion	NOUN
admet-510	41	48	phase	phase	NOUN
admet-510	41	49	(	(	PUNCT
admet-510	41	50	obtained	obtain	VERB
admet-510	41	51	by	by	ADP
admet-510	41	52	the	the	DET
admet-510	41	53	mobility	mobility	NOUN
admet-510	41	54	of	of	ADP
admet-510	41	55	the	the	DET
admet-510	41	56	microemulsion	microemulsion	NOUN
admet-510	41	57	marker	marker	NOUN
admet-510	41	58	)	)	PUNCT
admet-510	41	59	,	,	PUNCT
admet-510	41	60	and	and	CCONJ
admet-510	41	61	µ0	µ0	NOUN
admet-510	41	62	the	the	DET
admet-510	41	63	mobility	mobility	NOUN
admet-510	41	64	of	of	ADP
admet-510	41	65	the	the	DET
admet-510	41	66	compound	compound	NOUN
admet-510	41	67	in	in	ADP
admet-510	41	68	the	the	DET
admet-510	41	69	aqueous	aqueous	ADJ
admet-510	41	70	buffer	buffer	NOUN
admet-510	41	71	without	without	ADP
admet-510	41	72	the	the	DET
admet-510	41	73	microemulsion	microemulsion	NOUN
admet-510	41	74	,	,	PUNCT
admet-510	41	75	i.e.	i.e.	X
admet-510	41	76	,	,	PUNCT
admet-510	41	77	in	in	ADP
admet-510	41	78	capillary	capillary	ADJ
admet-510	41	79	zone	zone	NOUN
admet-510	41	80	electrophoresis	electrophoresis	NOUN
admet-510	41	81	(	(	PUNCT
admet-510	41	82	cze	cze	NOUN
admet-510	41	83	)	)	PUNCT
admet-510	41	84	.	.	PUNCT
admet-510	42	1	in	in	ADP
admet-510	42	2	parallel	parallel	ADJ
admet-510	42	3	studies	study	NOUN
admet-510	42	4	of	of	ADP
admet-510	42	5	the	the	DET
admet-510	42	6	research	research	NOUN
admet-510	42	7	group	group	NOUN
admet-510	42	8	,	,	PUNCT
admet-510	42	9	it	it	PRON
admet-510	42	10	has	have	AUX
admet-510	42	11	been	be	AUX
admet-510	42	12	observed	observe	VERB
admet-510	42	13	that	that	SCONJ
admet-510	42	14	the	the	DET
admet-510	42	15	viscosity	viscosity	NOUN
admet-510	42	16	of	of	ADP
admet-510	42	17	the	the	DET
admet-510	42	18	buffer	buffer	NOUN
admet-510	42	19	can	can	AUX
admet-510	42	20	affect	affect	VERB
admet-510	42	21	the	the	DET
admet-510	42	22	electrophoretic	electrophoretic	ADJ
admet-510	42	23	mobility	mobility	NOUN
admet-510	42	24	of	of	ADP
admet-510	42	25	the	the	DET
admet-510	42	26	compound	compound	NOUN
admet-510	42	27	.	.	PUNCT
admet-510	43	1	so	so	ADV
admet-510	43	2	,	,	PUNCT
admet-510	43	3	in	in	ADP
admet-510	43	4	order	order	NOUN
admet-510	43	5	to	to	PART
admet-510	43	6	determine	determine	VERB
admet-510	43	7	the	the	DET
admet-510	43	8	retention	retention	NOUN
admet-510	43	9	factor	factor	NOUN
admet-510	43	10	of	of	ADP
admet-510	43	11	ionizable	ionizable	ADJ
admet-510	43	12	acids	acid	NOUN
admet-510	43	13	,	,	PUNCT
admet-510	43	14	as	as	SCONJ
admet-510	43	15	solutions	solution	NOUN
admet-510	43	16	with	with	ADP
admet-510	43	17	different	different	ADJ
admet-510	43	18	viscosities	viscosity	NOUN
admet-510	43	19	have	have	AUX
admet-510	43	20	been	be	AUX
admet-510	43	21	used	use	VERB
admet-510	43	22	,	,	PUNCT
admet-510	43	23	a	a	DET
admet-510	43	24	viscosity	viscosity	NOUN
admet-510	43	25	correction	correction	NOUN
admet-510	43	26	factor	factor	NOUN
admet-510	43	27	has	have	VERB
admet-510	43	28	to	to	PART
admet-510	43	29	be	be	AUX
admet-510	43	30	introduced	introduce	VERB
admet-510	43	31	[	[	PUNCT
admet-510	43	32	7	7	NUM
admet-510	43	33	]	]	PUNCT
admet-510	43	34	.	.	PUNCT
admet-510	44	1	results	result	NOUN
admet-510	44	2	and	and	CCONJ
admet-510	44	3	discussion	discussion	NOUN
admet-510	44	4	in	in	ADP
admet-510	44	5	order	order	NOUN
admet-510	44	6	to	to	PART
admet-510	44	7	estimate	estimate	VERB
admet-510	44	8	the	the	DET
admet-510	44	9	log	log	NOUN
admet-510	44	10	do	do	AUX
admet-510	44	11	/	/	SYM
admet-510	44	12	w	w	NOUN
admet-510	44	13	values	value	NOUN
admet-510	44	14	of	of	ADP
admet-510	44	15	naproxen	naproxen	NOUN
admet-510	44	16	at	at	ADP
admet-510	44	17	several	several	ADJ
admet-510	44	18	degrees	degree	NOUN
admet-510	44	19	of	of	ADP
admet-510	44	20	ionization	ionization	NOUN
admet-510	44	21	through	through	ADP
admet-510	44	22	electrophoretic	electrophoretic	ADJ
admet-510	44	23	measurements	measurement	NOUN
admet-510	44	24	a	a	DET
admet-510	44	25	calibration	calibration	NOUN
admet-510	44	26	curve	curve	NOUN
admet-510	44	27	that	that	PRON
admet-510	44	28	correlates	correlate	VERB
admet-510	44	29	log	log	NOUN
admet-510	44	30	po	po	NOUN
admet-510	44	31	/	/	SYM
admet-510	44	32	w	w	PROPN
admet-510	44	33	vs.	vs.	ADP
admet-510	44	34	log	log	NOUN
admet-510	44	35	kmeekc	kmeekc	PROPN
admet-510	44	36	has	have	AUX
admet-510	44	37	been	be	AUX
admet-510	44	38	performed	perform	VERB
admet-510	44	39	.	.	PUNCT
admet-510	45	1	20	20	NUM
admet-510	45	2	neutral	neutral	ADJ
admet-510	45	3	compounds	compound	NOUN
admet-510	45	4	with	with	ADP
admet-510	45	5	known	know	VERB
admet-510	45	6	log	log	NOUN
admet-510	45	7	po	po	NOUN
admet-510	45	8	/	/	SYM
admet-510	45	9	w	w	NOUN
admet-510	45	10	values	value	NOUN
admet-510	45	11	[	[	X
admet-510	45	12	8,9	8,9	NUM
admet-510	45	13	]	]	PUNCT
admet-510	45	14	have	have	AUX
admet-510	45	15	been	be	AUX
admet-510	45	16	used	use	VERB
admet-510	45	17	to	to	PART
admet-510	45	18	establish	establish	VERB
admet-510	45	19	the	the	DET
admet-510	45	20	curve	curve	NOUN
admet-510	45	21	.	.	PUNCT
admet-510	46	1	the	the	DET
admet-510	46	2	substances	substance	NOUN
admet-510	46	3	that	that	PRON
admet-510	46	4	have	have	AUX
admet-510	46	5	been	be	AUX
admet-510	46	6	chosen	choose	VERB
admet-510	46	7	present	present	ADJ
admet-510	46	8	log	log	PROPN
admet-510	46	9	po	po	PROPN
admet-510	46	10	/	/	SYM
admet-510	46	11	w	w	NOUN
admet-510	46	12	values	value	NOUN
admet-510	46	13	uniformly	uniformly	ADV
admet-510	46	14	distributed	distribute	VERB
admet-510	46	15	between	between	ADP
admet-510	46	16	approximately	approximately	ADV
admet-510	46	17	0	0	NUM
admet-510	46	18	and	and	CCONJ
admet-510	46	19	4	4	NUM
admet-510	46	20	units	unit	NOUN
admet-510	46	21	.	.	PUNCT
admet-510	47	1	the	the	DET
admet-510	47	2	equation	equation	NOUN
admet-510	47	3	of	of	ADP
admet-510	47	4	the	the	DET
admet-510	47	5	calibration	calibration	NOUN
admet-510	47	6	curve	curve	NOUN
admet-510	47	7	obtained	obtain	VERB
admet-510	47	8	and	and	CCONJ
admet-510	47	9	their	their	PRON
admet-510	47	10	statistics	statistic	NOUN
admet-510	47	11	are	be	AUX
admet-510	47	12	as	as	SCONJ
admet-510	47	13	follows	follow	VERB
admet-510	47	14	:	:	PUNCT
admet-510	47	15	log	log	VERB
admet-510	47	16	po	po	NOUN
admet-510	47	17	/	/	SYM
admet-510	47	18	w	w	PROPN
admet-510	47	19	=	=	NOUN
admet-510	47	20	1.60	1.60	NUM
admet-510	47	21	(	(	PUNCT
admet-510	47	22	±0.11)·log	±0.11)·log	PROPN
admet-510	47	23	kmeekc	kmeekc	NOUN
admet-510	47	24	+	+	CCONJ
admet-510	47	25	1.51	1.51	NUM
admet-510	47	26	(	(	PUNCT
admet-510	47	27	±0.08	±0.08	PROPN
admet-510	47	28	)	)	PUNCT
admet-510	47	29	,	,	PUNCT
admet-510	47	30	r2=0.92	r2=0.92	NOUN
admet-510	47	31	;	;	PUNCT
admet-510	47	32	sd=0.33	sd=0.33	NOUN
admet-510	47	33	;	;	PUNCT
admet-510	47	34	n=20	n=20	NOUN
admet-510	47	35	,	,	PUNCT
admet-510	47	36	(	(	PUNCT
admet-510	47	37	4	4	X
admet-510	47	38	)	)	PUNCT
admet-510	47	39	as	as	SCONJ
admet-510	47	40	expected	expect	VERB
admet-510	47	41	,	,	PUNCT
admet-510	47	42	equation	equation	NOUN
admet-510	47	43	4	4	NUM
admet-510	47	44	shows	show	VERB
admet-510	47	45	a	a	DET
admet-510	47	46	good	good	ADJ
admet-510	47	47	correlation	correlation	NOUN
admet-510	47	48	between	between	ADP
admet-510	47	49	log	log	PROPN
admet-510	47	50	po	po	PROPN
admet-510	47	51	/	/	SYM
admet-510	47	52	w	w	PROPN
admet-510	47	53	and	and	CCONJ
admet-510	47	54	log	log	VERB
admet-510	47	55	kmeekc	kmeekc	PROPN
admet-510	47	56	for	for	ADP
admet-510	47	57	neutral	neutral	ADJ
admet-510	47	58	compounds	compound	NOUN
admet-510	47	59	,	,	PUNCT
admet-510	47	60	and	and	CCONJ
admet-510	47	61	it	it	PRON
admet-510	47	62	is	be	AUX
admet-510	47	63	very	very	ADV
admet-510	47	64	similar	similar	ADJ
admet-510	47	65	to	to	ADP
admet-510	47	66	equations	equation	NOUN
admet-510	47	67	1	1	NUM
admet-510	47	68	and	and	CCONJ
admet-510	47	69	2	2	NUM
admet-510	47	70	.	.	X
admet-510	48	1	as	as	SCONJ
admet-510	48	2	the	the	DET
admet-510	48	3	retention	retention	NOUN
admet-510	48	4	factor	factor	NOUN
admet-510	48	5	of	of	ADP
admet-510	48	6	acidic	acidic	ADJ
admet-510	48	7	compounds	compound	NOUN
admet-510	48	8	is	be	AUX
admet-510	48	9	the	the	DET
admet-510	48	10	weighted	weighted	ADJ
admet-510	48	11	average	average	NOUN
admet-510	48	12	of	of	ADP
admet-510	48	13	the	the	DET
admet-510	48	14	retention	retention	NOUN
admet-510	48	15	factor	factor	NOUN
admet-510	48	16	of	of	ADP
admet-510	48	17	the	the	DET
admet-510	48	18	neutral	neutral	ADJ
admet-510	48	19	(	(	PUNCT
admet-510	48	20	k(ha	k(ha	PROPN
admet-510	48	21	)	)	PUNCT
admet-510	48	22	)	)	PUNCT
admet-510	48	23	and	and	CCONJ
admet-510	48	24	the	the	DET
admet-510	48	25	fully	fully	ADV
admet-510	48	26	ionized	ionized	ADJ
admet-510	48	27	(	(	PUNCT
admet-510	48	28	k(a-	k(a-	NOUN
admet-510	48	29	)	)	PUNCT
admet-510	48	30	)	)	PUNCT
admet-510	48	31	forms	form	NOUN
admet-510	48	32	of	of	ADP
admet-510	48	33	the	the	DET
admet-510	48	34	compound	compound	NOUN
admet-510	48	35	:	:	PUNCT
admet-510	48	36	𝑘	𝑘	X
admet-510	48	37	=	=	PUNCT
admet-510	48	38	(	(	PUNCT
admet-510	48	39	1	1	NUM
admet-510	48	40	−	−	PROPN
admet-510	48	41	α	α	NUM
admet-510	48	42	)	)	PUNCT
admet-510	48	43	·	·	PUNCT
admet-510	49	1	𝑘(𝐻𝐴	𝑘(𝐻𝐴	NOUN
admet-510	49	2	)	)	PUNCT
admet-510	50	1	+	+	CCONJ
admet-510	50	2	α	α	PROPN
admet-510	50	3	·	·	PUNCT
admet-510	50	4	𝑘(𝐴−	𝑘(𝐴−	NUM
admet-510	50	5	)	)	PUNCT
admet-510	50	6	,	,	PUNCT
admet-510	50	7	(	(	PUNCT
admet-510	50	8	5	5	NUM
admet-510	50	9	)	)	PUNCT
admet-510	50	10	and	and	CCONJ
admet-510	50	11	the	the	DET
admet-510	50	12	ionization	ionization	NOUN
admet-510	50	13	degree	degree	NOUN
admet-510	50	14	(	(	PUNCT
admet-510	50	15	α	α	NOUN
admet-510	50	16	)	)	PUNCT
admet-510	50	17	can	can	AUX
admet-510	50	18	be	be	AUX
admet-510	50	19	calculated	calculate	VERB
admet-510	50	20	using	use	VERB
admet-510	50	21	the	the	DET
admet-510	50	22	following	follow	VERB
admet-510	50	23	formula	formula	NOUN
admet-510	50	24	:	:	PUNCT
admet-510	50	25	α	α	X
admet-510	50	26	=	=	SYM
admet-510	50	27	10ph−p𝐾a	10ph−p𝐾a	NUM
admet-510	50	28	1	1	NUM
admet-510	50	29	+	+	NUM
admet-510	50	30	10ph−p𝐾a	10ph−p𝐾a	NUM
admet-510	50	31	,	,	PUNCT
admet-510	50	32	(	(	PUNCT
admet-510	50	33	6	6	NUM
admet-510	50	34	)	)	PUNCT
admet-510	50	35	an	an	DET
admet-510	50	36	equation	equation	NOUN
admet-510	50	37	that	that	PRON
admet-510	50	38	relates	relate	VERB
admet-510	50	39	retention	retention	NOUN
admet-510	50	40	factor	factor	NOUN
admet-510	50	41	to	to	ADP
admet-510	50	42	ph	ph	NOUN
admet-510	50	43	can	can	AUX
admet-510	50	44	be	be	AUX
admet-510	50	45	easily	easily	ADV
admet-510	50	46	obtained	obtain	VERB
admet-510	50	47	[	[	PUNCT
admet-510	50	48	6	6	NUM
admet-510	50	49	]	]	PUNCT
admet-510	50	50	:	:	PUNCT
admet-510	51	1	𝑘	𝑘	X
admet-510	51	2	=	=	PUNCT
admet-510	52	1	𝑘(𝐻𝐴)+𝑘(𝐴−)·10ph−p𝐾a	𝑘(𝐻𝐴)+𝑘(𝐴−)·10ph−p𝐾a	PROPN
admet-510	52	2	1	1	NUM
admet-510	52	3	+	+	NOUN
admet-510	52	4	10ph−p𝐾a	10ph−p𝐾a	NUM
admet-510	52	5	.	.	PUNCT
admet-510	53	1	(	(	PUNCT
admet-510	53	2	7	7	X
admet-510	53	3	)	)	PUNCT
admet-510	53	4	to	to	PART
admet-510	53	5	study	study	VERB
admet-510	53	6	the	the	DET
admet-510	53	7	applicability	applicability	NOUN
admet-510	53	8	of	of	ADP
admet-510	53	9	the	the	DET
admet-510	53	10	method	method	NOUN
admet-510	53	11	to	to	PART
admet-510	53	12	ionizable	ionizable	ADJ
admet-510	53	13	acidic	acidic	ADJ
admet-510	53	14	compounds	compound	NOUN
admet-510	53	15	,	,	PUNCT
admet-510	53	16	the	the	DET
admet-510	53	17	retention	retention	NOUN
admet-510	53	18	factor	factor	NOUN
admet-510	53	19	of	of	ADP
admet-510	53	20	naproxen	naproxen	NOUN
admet-510	53	21	has	have	AUX
admet-510	53	22	been	be	AUX
admet-510	53	23	measured	measure	VERB
admet-510	53	24	in	in	ADP
admet-510	53	25	the	the	DET
admet-510	53	26	meekc	meekc	ADJ
admet-510	53	27	system	system	NOUN
admet-510	53	28	at	at	ADP
admet-510	53	29	6	6	NUM
admet-510	53	30	different	different	ADJ
admet-510	53	31	ph	ph	ADJ
admet-510	53	32	values	value	NOUN
admet-510	53	33	,	,	PUNCT
admet-510	53	34	ranging	range	VERB
admet-510	53	35	from	from	ADP
admet-510	53	36	2	2	NUM
admet-510	53	37	to	to	ADP
admet-510	53	38	7	7	NUM
admet-510	53	39	(	(	PUNCT
admet-510	53	40	covering	cover	VERB
admet-510	53	41	all	all	PRON
admet-510	53	42	of	of	ADP
admet-510	53	43	the	the	DET
admet-510	53	44	degrees	degree	NOUN
admet-510	53	45	of	of	ADP
admet-510	53	46	ionization	ionization	NOUN
admet-510	53	47	of	of	ADP
admet-510	53	48	the	the	DET
admet-510	53	49	acid	acid	NOUN
admet-510	53	50	)	)	PUNCT
admet-510	53	51	.	.	PUNCT
admet-510	54	1	then	then	ADV
admet-510	54	2	equation	equation	NOUN
admet-510	54	3	7	7	NUM
admet-510	54	4	has	have	AUX
admet-510	54	5	been	be	AUX
admet-510	54	6	fitted	fit	VERB
admet-510	54	7	to	to	ADP
admet-510	54	8	the	the	DET
admet-510	54	9	measured	measured	ADJ
admet-510	54	10	retention	retention	NOUN
admet-510	54	11	factors	factor	NOUN
admet-510	54	12	.	.	PUNCT
admet-510	55	1	figure	figure	NOUN
admet-510	55	2	1	1	NUM
admet-510	55	3	shows	show	VERB
admet-510	55	4	the	the	DET
admet-510	55	5	experimental	experimental	ADJ
admet-510	55	6	values	value	NOUN
admet-510	55	7	(	(	PUNCT
admet-510	55	8	x	x	X
admet-510	55	9	)	)	PUNCT
admet-510	55	10	and	and	CCONJ
admet-510	55	11	the	the	DET
admet-510	55	12	retention	retention	NOUN
admet-510	55	13	-	-	PUNCT
admet-510	55	14	ph	ph	NOUN
admet-510	55	15	profile	profile	NOUN
admet-510	55	16	obtained	obtain	VERB
admet-510	55	17	by	by	ADP
admet-510	55	18	fitting	fitting	ADJ
admet-510	55	19	equation	equation	NOUN
admet-510	55	20	7	7	NUM
admet-510	55	21	to	to	ADP
admet-510	55	22	the	the	DET
admet-510	55	23	experimental	experimental	ADJ
admet-510	55	24	data	datum	NOUN
admet-510	55	25	(	(	PUNCT
admet-510	55	26	solid	solid	ADJ
admet-510	55	27	line	line	NOUN
admet-510	55	28	)	)	PUNCT
admet-510	55	29	.	.	PUNCT
admet-510	56	1	susana	susana	PROPN
admet-510	56	2	amézqueta	amézqueta	PROPN
admet-510	56	3	et	et	PROPN
admet-510	56	4	al	al	PROPN
admet-510	56	5	.	.	PROPN
admet-510	56	6	admet	admet	PROPN
admet-510	56	7	&	&	CCONJ
admet-510	56	8	dmpk	dmpk	PROPN
admet-510	56	9	6(1	6(1	NUM
admet-510	56	10	)	)	PUNCT
admet-510	56	11	(	(	PUNCT
admet-510	56	12	2018	2018	NUM
admet-510	56	13	)	)	PUNCT
admet-510	56	14	55	55	NUM
admet-510	56	15	-	-	SYM
admet-510	56	16	60	60	NUM
admet-510	56	17	58	58	NUM
admet-510	56	18	figure	figure	NOUN
admet-510	56	19	1	1	NUM
admet-510	56	20	.	.	PUNCT
admet-510	56	21	retention	retention	NOUN
admet-510	56	22	factor	factor	NOUN
admet-510	56	23	-	-	PUNCT
admet-510	56	24	ph	ph	NOUN
admet-510	56	25	profile	profile	NOUN
admet-510	56	26	of	of	ADP
admet-510	56	27	naproxen	naproxen	NOUN
admet-510	56	28	.	.	PUNCT
admet-510	57	1	the	the	DET
admet-510	57	2	parameters	parameter	NOUN
admet-510	57	3	obtained	obtain	VERB
admet-510	57	4	from	from	ADP
admet-510	57	5	the	the	DET
admet-510	57	6	retention	retention	NOUN
admet-510	57	7	profile	profile	NOUN
admet-510	57	8	in	in	ADP
admet-510	57	9	figure	figure	NOUN
admet-510	57	10	1	1	NUM
admet-510	57	11	,	,	PUNCT
admet-510	57	12	with	with	ADP
admet-510	57	13	their	their	PRON
admet-510	57	14	respective	respective	ADJ
admet-510	57	15	statistics	statistic	NOUN
admet-510	57	16	are	be	AUX
admet-510	57	17	:	:	PUNCT
admet-510	57	18	k(ha	k(ha	X
admet-510	57	19	)	)	PUNCT
admet-510	57	20	=	=	NOUN
admet-510	57	21	8.24	8.24	NUM
admet-510	57	22	(	(	PUNCT
admet-510	57	23	±0.13	±0.13	PROPN
admet-510	57	24	)	)	PUNCT
admet-510	57	25	;	;	PUNCT
admet-510	57	26	k(a-	k(a-	ADJ
admet-510	57	27	)	)	PUNCT
admet-510	57	28	=	=	SYM
admet-510	57	29	0.40	0.40	NUM
admet-510	57	30	(	(	PUNCT
admet-510	57	31	±0.11	±0.11	PROPN
admet-510	57	32	)	)	PUNCT
admet-510	57	33	;	;	PUNCT
admet-510	58	1	pka	pka	PROPN
admet-510	58	2	=	=	PUNCT
admet-510	58	3	4.38	4.38	NUM
admet-510	58	4	(	(	PUNCT
admet-510	58	5	±0.04	±0.04	PROPN
admet-510	58	6	)	)	PUNCT
admet-510	58	7	;	;	PUNCT
admet-510	58	8	(	(	PUNCT
admet-510	58	9	r2	r2	PROPN
admet-510	58	10	=	=	PUNCT
admet-510	58	11	0.999	0.999	NUM
admet-510	58	12	;	;	PUNCT
admet-510	58	13	f	f	PROPN
admet-510	58	14	=	=	SYM
admet-510	58	15	1223	1223	NUM
admet-510	58	16	;	;	PUNCT
admet-510	58	17	sd	sd	ADP
admet-510	58	18	=	=	SYM
admet-510	58	19	0.16	0.16	NUM
admet-510	58	20	)	)	PUNCT
admet-510	58	21	.	.	PUNCT
admet-510	59	1	using	use	VERB
admet-510	59	2	equation	equation	NOUN
admet-510	59	3	4	4	NUM
admet-510	59	4	,	,	PUNCT
admet-510	59	5	and	and	CCONJ
admet-510	59	6	k(ha	k(ha	NOUN
admet-510	59	7	)	)	PUNCT
admet-510	59	8	and	and	CCONJ
admet-510	59	9	k(a-	k(a-	NOUN
admet-510	59	10	)	)	PUNCT
admet-510	59	11	obtained	obtain	VERB
admet-510	59	12	from	from	ADP
admet-510	59	13	the	the	DET
admet-510	59	14	fit	fit	NOUN
admet-510	59	15	of	of	ADP
admet-510	59	16	equation	equation	NOUN
admet-510	59	17	7	7	NUM
admet-510	59	18	(	(	PUNCT
admet-510	59	19	figure	figure	NOUN
admet-510	59	20	1	1	NUM
admet-510	59	21	)	)	PUNCT
admet-510	59	22	,	,	PUNCT
admet-510	59	23	the	the	DET
admet-510	59	24	logarithm	logarithm	NOUN
admet-510	59	25	of	of	ADP
admet-510	59	26	the	the	DET
admet-510	59	27	octanol	octanol	NOUN
admet-510	59	28	-	-	PUNCT
admet-510	59	29	water	water	NOUN
admet-510	59	30	partition	partition	NOUN
admet-510	59	31	coefficient	coefficient	NOUN
admet-510	59	32	of	of	ADP
admet-510	59	33	the	the	DET
admet-510	59	34	neutral	neutral	ADJ
admet-510	59	35	and	and	CCONJ
admet-510	59	36	fully	fully	ADV
admet-510	59	37	ionized	ionized	ADJ
admet-510	59	38	forms	form	NOUN
admet-510	59	39	of	of	ADP
admet-510	59	40	the	the	DET
admet-510	59	41	acid	acid	NOUN
admet-510	59	42	can	can	AUX
admet-510	59	43	be	be	AUX
admet-510	59	44	calculated	calculate	VERB
admet-510	59	45	:	:	PUNCT
admet-510	59	46	log	log	VERB
admet-510	59	47	po	po	NOUN
admet-510	59	48	/	/	SYM
admet-510	59	49	w(ha)=2.97	w(ha)=2.97	NOUN
admet-510	59	50	and	and	CCONJ
admet-510	59	51	log	log	VERB
admet-510	59	52	po	po	NOUN
admet-510	59	53	/	/	SYM
admet-510	59	54	w(a-)=0.87	w(a-)=0.87	PROPN
admet-510	59	55	,	,	PUNCT
admet-510	59	56	respectively	respectively	ADV
admet-510	59	57	.	.	PUNCT
admet-510	60	1	similarly	similarly	ADV
admet-510	60	2	to	to	ADP
admet-510	60	3	the	the	DET
admet-510	60	4	retention	retention	NOUN
admet-510	60	5	factor	factor	NOUN
admet-510	60	6	,	,	PUNCT
admet-510	60	7	the	the	DET
admet-510	60	8	octanol	octanol	NOUN
admet-510	60	9	-	-	PUNCT
admet-510	60	10	water	water	NOUN
admet-510	60	11	distribution	distribution	NOUN
admet-510	60	12	coefficient	coefficient	NOUN
admet-510	60	13	(	(	PUNCT
admet-510	60	14	do	do	AUX
admet-510	60	15	/	/	SYM
admet-510	60	16	w	w	NOUN
admet-510	60	17	)	)	PUNCT
admet-510	60	18	is	be	AUX
admet-510	60	19	also	also	ADV
admet-510	60	20	related	relate	VERB
admet-510	60	21	to	to	ADP
admet-510	60	22	the	the	DET
admet-510	60	23	ionization	ionization	NOUN
admet-510	60	24	degree	degree	NOUN
admet-510	60	25	of	of	ADP
admet-510	60	26	the	the	DET
admet-510	60	27	compound	compound	NOUN
admet-510	60	28	through	through	ADP
admet-510	60	29	the	the	DET
admet-510	60	30	following	follow	VERB
admet-510	60	31	equation	equation	NOUN
admet-510	60	32	:	:	PUNCT
admet-510	61	1	𝐷o	𝐷o	PROPN
admet-510	61	2	/	/	SYM
admet-510	61	3	w	w	NOUN
admet-510	61	4	=	=	PUNCT
admet-510	61	5	(	(	PUNCT
admet-510	61	6	1	1	NUM
admet-510	61	7	−	−	PROPN
admet-510	61	8	α	α	NOUN
admet-510	61	9	)	)	PUNCT
admet-510	61	10	·	·	PUNCT
admet-510	62	1	𝑃o	𝑃o	NOUN
admet-510	62	2	/	/	SYM
admet-510	62	3	w(ha	w(ha	NOUN
admet-510	62	4	)	)	PUNCT
admet-510	63	1	+	+	CCONJ
admet-510	63	2	α	α	PROPN
admet-510	63	3	·	·	PUNCT
admet-510	63	4	𝑃o	𝑃o	PROPN
admet-510	63	5	/	/	SYM
admet-510	63	6	w(a−	w(a−	PROPN
admet-510	63	7	)	)	PUNCT
admet-510	63	8	.	.	PUNCT
admet-510	64	1	(	(	PUNCT
admet-510	64	2	8)	8)	NUM
admet-510	64	3	so	so	ADV
admet-510	64	4	,	,	PUNCT
admet-510	64	5	using	use	VERB
admet-510	64	6	equation	equation	NOUN
admet-510	64	7	8	8	NUM
admet-510	64	8	and	and	CCONJ
admet-510	64	9	considering	consider	VERB
admet-510	64	10	the	the	DET
admet-510	64	11	pka	pka	PROPN
admet-510	64	12	value	value	NOUN
admet-510	64	13	of	of	ADP
admet-510	64	14	the	the	DET
admet-510	64	15	compound	compound	NOUN
admet-510	64	16	(	(	PUNCT
admet-510	64	17	pka=4.38	pka=4.38	PROPN
admet-510	64	18	,	,	PUNCT
admet-510	64	19	obtained	obtain	VERB
admet-510	64	20	from	from	ADP
admet-510	64	21	figure	figure	NOUN
admet-510	64	22	1	1	NUM
admet-510	64	23	data	datum	NOUN
admet-510	64	24	)	)	PUNCT
admet-510	64	25	it	it	PRON
admet-510	64	26	is	be	AUX
admet-510	64	27	possible	possible	ADJ
admet-510	64	28	to	to	PART
admet-510	64	29	estimate	estimate	VERB
admet-510	64	30	the	the	DET
admet-510	64	31	log	log	NOUN
admet-510	64	32	do	do	VERB
admet-510	64	33	/	/	SYM
admet-510	64	34	w	w	NOUN
admet-510	64	35	of	of	ADP
admet-510	64	36	naproxen	naproxen	NOUN
admet-510	64	37	at	at	ADP
admet-510	64	38	any	any	DET
admet-510	64	39	degree	degree	NOUN
admet-510	64	40	of	of	ADP
admet-510	64	41	ionization	ionization	NOUN
admet-510	64	42	.	.	PUNCT
admet-510	65	1	table	table	NOUN
admet-510	65	2	1	1	NUM
admet-510	65	3	presents	present	VERB
admet-510	65	4	the	the	DET
admet-510	65	5	experimental	experimental	ADJ
admet-510	65	6	log	log	NOUN
admet-510	65	7	do	do	AUX
admet-510	65	8	/	/	SYM
admet-510	66	1	w	w	NOUN
admet-510	67	1	values	value	NOUN
admet-510	67	2	reported	report	VERB
admet-510	67	3	in	in	ADP
admet-510	67	4	the	the	DET
admet-510	67	5	literature	literature	NOUN
admet-510	67	6	determined	determine	VERB
admet-510	67	7	by	by	ADP
admet-510	67	8	the	the	DET
admet-510	67	9	shake	shake	NOUN
admet-510	67	10	-	-	PUNCT
admet-510	67	11	flask	flask	NOUN
admet-510	67	12	[	[	X
admet-510	67	13	4	4	NUM
admet-510	67	14	]	]	PUNCT
admet-510	67	15	or	or	CCONJ
admet-510	67	16	the	the	DET
admet-510	67	17	ph	ph	ADJ
admet-510	67	18	-	-	ADJ
admet-510	67	19	metric	metric	ADJ
admet-510	67	20	methods	method	NOUN
admet-510	67	21	[	[	X
admet-510	67	22	5	5	NUM
admet-510	67	23	]	]	PUNCT
admet-510	67	24	,	,	PUNCT
admet-510	67	25	and	and	CCONJ
admet-510	67	26	the	the	DET
admet-510	67	27	log	log	NOUN
admet-510	67	28	do	do	VERB
admet-510	67	29	/	/	SYM
admet-510	67	30	w	w	NOUN
admet-510	67	31	estimated	estimate	VERB
admet-510	67	32	values	value	NOUN
admet-510	67	33	which	which	PRON
admet-510	67	34	have	have	AUX
admet-510	67	35	been	be	AUX
admet-510	67	36	calculated	calculate	VERB
admet-510	67	37	using	use	VERB
admet-510	67	38	equation	equation	NOUN
admet-510	67	39	8	8	NUM
admet-510	67	40	.	.	PUNCT
admet-510	67	41	table	table	NOUN
admet-510	67	42	1	1	NUM
admet-510	67	43	.	.	PUNCT
admet-510	68	1	differences	difference	NOUN
admet-510	68	2	between	between	ADP
admet-510	68	3	literature	literature	NOUN
admet-510	68	4	and	and	CCONJ
admet-510	68	5	estimated	estimate	VERB
admet-510	68	6	log	log	NOUN
admet-510	68	7	do	do	AUX
admet-510	68	8	/	/	SYM
admet-510	68	9	w	w	NOUN
admet-510	68	10	values	value	NOUN
admet-510	68	11	of	of	ADP
admet-510	68	12	naproxen	naproxen	NOUN
admet-510	68	13	at	at	ADP
admet-510	68	14	several	several	ADJ
admet-510	68	15	ph	ph	ADJ
admet-510	68	16	values	value	NOUN
admet-510	68	17	.	.	PUNCT
admet-510	69	1	ph	ph	ADJ
admet-510	69	2	log	log	NOUN
admet-510	69	3	do	do	AUX
admet-510	69	4	/	/	SYM
admet-510	69	5	w	w	PROPN
admet-510	69	6	(	(	PUNCT
admet-510	69	7	literature	literature	NOUN
admet-510	69	8	)	)	PUNCT
admet-510	69	9	α	α	PROPN
admet-510	69	10	(	(	PUNCT
admet-510	69	11	1	1	NUM
admet-510	69	12	-	-	PUNCT
admet-510	69	13	α)·do	α)·do	NOUN
admet-510	69	14	/	/	SYM
admet-510	69	15	w(ha	w(ha	NOUN
admet-510	69	16	)	)	PUNCT
admet-510	69	17	α·do	α·do	PROPN
admet-510	69	18	/	/	SYM
admet-510	69	19	w(a-	w(a-	PROPN
admet-510	69	20	)	)	PUNCT
admet-510	69	21	log	log	NOUN
admet-510	69	22	do	do	AUX
admet-510	69	23	/	/	SYM
admet-510	69	24	w	w	PROPN
admet-510	69	25	(	(	PUNCT
admet-510	69	26	estimated	estimate	VERB
admet-510	69	27	)	)	PUNCT
admet-510	69	28	log	log	PROPN
admet-510	69	29	dlit.-log	dlit.-log	NOUN
admet-510	69	30	dest	dest	ADV
admet-510	69	31	.	.	PUNCT
admet-510	70	1	1.00	1.00	NUM
admet-510	70	2	a	a	DET
admet-510	70	3	3.35	3.35	NUM
admet-510	70	4	0.000	0.000	NUM
admet-510	70	5	942.36	942.36	NUM
admet-510	70	6	0.00	0.00	NUM
admet-510	70	7	2.97	2.97	NUM
admet-510	70	8	0.38	0.38	NUM
admet-510	70	9	2.00	2.00	NUM
admet-510	70	10	a	a	DET
admet-510	70	11	3.34	3.34	NUM
admet-510	70	12	0.004	0.004	NUM
admet-510	70	13	938.84	938.84	NUM
admet-510	70	14	0.03	0.03	NUM
admet-510	70	15	2.97	2.97	NUM
admet-510	70	16	0.37	0.37	NUM
admet-510	70	17	3.35	3.35	NUM
admet-510	70	18	a	a	DET
admet-510	70	19	3.05	3.05	NUM
admet-510	70	20	0.085	0.085	NUM
admet-510	70	21	862.28	862.28	NUM
admet-510	70	22	0.63	0.63	NUM
admet-510	70	23	2.94	2.94	NUM
admet-510	70	24	0.11	0.11	NUM
admet-510	70	25	4.50	4.50	NUM
admet-510	70	26	a	a	DET
admet-510	70	27	2.68	2.68	NUM
admet-510	70	28	0.569	0.569	NUM
admet-510	71	1	406.67	406.67	NUM
admet-510	71	2	4.22	4.22	NUM
admet-510	71	3	2.61	2.61	NUM
admet-510	71	4	0.07	0.07	NUM
admet-510	71	5	5.50	5.50	NUM
admet-510	71	6	a	a	DET
admet-510	71	7	2.07	2.07	NUM
admet-510	71	8	0.929	0.929	NUM
admet-510	71	9	66.47	66.47	NUM
admet-510	71	10	6.90	6.90	NUM
admet-510	71	11	1.87	1.87	NUM
admet-510	71	12	0.20	0.20	NUM
admet-510	71	13	5.5	5.5	NUM
admet-510	71	14	b	b	NOUN
admet-510	71	15	2.1	2.1	NUM
admet-510	71	16	0.929	0.929	NUM
admet-510	71	17	66.47	66.47	NUM
admet-510	71	18	6.90	6.90	NUM
admet-510	71	19	1.9	1.9	NUM
admet-510	71	20	0.2	0.2	NUM
admet-510	71	21	6.5	6.5	NUM
admet-510	71	22	b	b	NOUN
admet-510	71	23	1.1	1.1	NUM
admet-510	71	24	0.992	0.992	NUM
admet-510	71	25	7.10	7.10	NUM
admet-510	71	26	7.37	7.37	NUM
admet-510	71	27	1.2	1.2	NUM
admet-510	71	28	-0.1	-0.1	NOUN
admet-510	71	29	6.70	6.70	NUM
admet-510	71	30	a	a	DET
admet-510	71	31	0.79	0.79	NUM
admet-510	71	32	0.995	0.995	NUM
admet-510	71	33	4.49	4.49	NUM
admet-510	71	34	7.39	7.39	NUM
admet-510	71	35	1.07	1.07	NUM
admet-510	71	36	-0.28	-0.28	NUM
admet-510	71	37	7.40	7.40	NUM
admet-510	71	38	a	a	DET
admet-510	71	39	0.33	0.33	NUM
admet-510	71	40	0.999	0.999	NUM
admet-510	71	41	0.90	0.90	NUM
admet-510	71	42	7.42	7.42	NUM
admet-510	71	43	0.92	0.92	NUM
admet-510	71	44	-0.59	-0.59	NUM
admet-510	71	45	7.4	7.4	NUM
admet-510	71	46	b	b	PROPN
admet-510	71	47	0.3	0.3	NUM
admet-510	71	48	0.999	0.999	NUM
admet-510	71	49	0.90	0.90	NUM
admet-510	71	50	7.42	7.42	NUM
admet-510	71	51	0.9	0.9	NUM
admet-510	71	52	-0.6	-0.6	X
admet-510	71	53	8.20	8.20	NUM
admet-510	71	54	a	a	DET
admet-510	71	55	0.27	0.27	NUM
admet-510	71	56	1.000	1.000	NUM
admet-510	71	57	0.14	0.14	NUM
admet-510	71	58	7.43	7.43	NUM
admet-510	71	59	0.88	0.88	NUM
admet-510	71	60	-0.61	-0.61	NOUN
admet-510	71	61	9.20	9.20	NUM
admet-510	71	62	a	a	DET
admet-510	71	63	0.25	0.25	NUM
admet-510	71	64	1.000	1.000	NUM
admet-510	71	65	0.01	0.01	NUM
admet-510	71	66	7.43	7.43	NUM
admet-510	71	67	0.87	0.87	NUM
admet-510	71	68	-0.62	-0.62	NUM
admet-510	71	69	a	a	DET
admet-510	71	70	)	)	PUNCT
admet-510	71	71	data	datum	NOUN
admet-510	71	72	obtained	obtain	VERB
admet-510	71	73	from	from	ADP
admet-510	71	74	ref	ref	NOUN
admet-510	71	75	.	.	PUNCT
admet-510	72	1	[	[	X
admet-510	72	2	4	4	NUM
admet-510	72	3	]	]	PUNCT
admet-510	72	4	.	.	PUNCT
admet-510	73	1	b	b	X
admet-510	73	2	)	)	PUNCT
admet-510	73	3	data	datum	NOUN
admet-510	73	4	obtained	obtain	VERB
admet-510	73	5	from	from	ADP
admet-510	73	6	ref	ref	NOUN
admet-510	73	7	.	.	PUNCT
admet-510	74	1	[	[	X
admet-510	74	2	5	5	NUM
admet-510	74	3	]	]	PUNCT
admet-510	74	4	.	.	PUNCT
admet-510	75	1	0.0	0.0	NUM
admet-510	75	2	2.0	2.0	NUM
admet-510	75	3	4.0	4.0	NUM
admet-510	75	4	6.0	6.0	NUM
admet-510	75	5	8.0	8.0	NUM
admet-510	75	6	10.0	10.0	NUM
admet-510	75	7	1.0	1.0	NUM
admet-510	75	8	3.0	3.0	NUM
admet-510	75	9	5.0	5.0	NUM
admet-510	75	10	7.0	7.0	NUM
admet-510	75	11	9.0	9.0	NUM
admet-510	75	12	k	k	NOUN
admet-510	75	13	ph	ph	PROPN
admet-510	75	14	admet	admet	PROPN
admet-510	75	15	&	&	CCONJ
admet-510	75	16	dmpk	dmpk	PROPN
admet-510	75	17	6(1	6(1	NUM
admet-510	75	18	)	)	PUNCT
admet-510	75	19	(	(	PUNCT
admet-510	75	20	2018	2018	NUM
admet-510	75	21	)	)	PUNCT
admet-510	75	22	55	55	NUM
admet-510	75	23	-	-	SYM
admet-510	75	24	60	60	NUM
admet-510	75	25	estimation	estimation	NOUN
admet-510	75	26	of	of	ADP
admet-510	75	27	octanol	octanol	NOUN
admet-510	75	28	-	-	PUNCT
admet-510	75	29	water	water	NOUN
admet-510	75	30	log	log	NOUN
admet-510	75	31	do	do	AUX
admet-510	75	32	/	/	SYM
admet-510	75	33	w	w	NOUN
admet-510	75	34	of	of	ADP
admet-510	75	35	acidic	acidic	ADJ
admet-510	75	36	drugs	drug	NOUN
admet-510	75	37	by	by	ADP
admet-510	75	38	meekc	meekc	ADJ
admet-510	75	39	doi	doi	PROPN
admet-510	75	40	:	:	PUNCT
admet-510	75	41	10.5599	10.5599	NUM
admet-510	75	42	/	/	SYM
admet-510	75	43	admet.6.1.510	admet.6.1.510	NUM
admet-510	75	44	59	59	NUM
admet-510	75	45	the	the	DET
admet-510	75	46	differences	difference	NOUN
admet-510	75	47	between	between	ADP
admet-510	75	48	estimated	estimate	VERB
admet-510	75	49	(	(	PUNCT
admet-510	75	50	obtained	obtain	VERB
admet-510	75	51	by	by	ADP
admet-510	75	52	meekc	meekc	ADJ
admet-510	75	53	measurements	measurement	NOUN
admet-510	75	54	)	)	PUNCT
admet-510	75	55	and	and	CCONJ
admet-510	75	56	literature	literature	NOUN
admet-510	75	57	log	log	NOUN
admet-510	75	58	do	do	AUX
admet-510	75	59	/	/	SYM
admet-510	75	60	w	w	NOUN
admet-510	75	61	data	datum	NOUN
admet-510	75	62	are	be	AUX
admet-510	75	63	in	in	ADP
admet-510	75	64	most	most	ADJ
admet-510	75	65	cases	case	NOUN
admet-510	75	66	under	under	ADP
admet-510	75	67	0.4	0.4	NUM
admet-510	75	68	.	.	PUNCT
admet-510	76	1	higher	high	ADJ
admet-510	76	2	differences	difference	NOUN
admet-510	76	3	have	have	AUX
admet-510	76	4	been	be	AUX
admet-510	76	5	observed	observe	VERB
admet-510	76	6	only	only	ADV
admet-510	76	7	at	at	ADP
admet-510	76	8	those	those	DET
admet-510	76	9	values	value	NOUN
admet-510	76	10	of	of	ADP
admet-510	76	11	ph	ph	NOUN
admet-510	76	12	where	where	SCONJ
admet-510	76	13	the	the	DET
admet-510	76	14	acid	acid	NOUN
admet-510	76	15	is	be	AUX
admet-510	76	16	highly	highly	ADV
admet-510	76	17	or	or	CCONJ
admet-510	76	18	fully	fully	ADV
admet-510	76	19	ionized	ionized	ADJ
admet-510	76	20	(	(	PUNCT
admet-510	76	21	>	>	SYM
admet-510	76	22	99.5	99.5	NUM
admet-510	76	23	%	%	NOUN
admet-510	76	24	)	)	PUNCT
admet-510	76	25	.	.	PUNCT
admet-510	77	1	this	this	DET
admet-510	77	2	higher	high	ADJ
admet-510	77	3	error	error	NOUN
admet-510	77	4	could	could	AUX
admet-510	77	5	be	be	AUX
admet-510	77	6	explained	explain	VERB
admet-510	77	7	due	due	ADP
admet-510	77	8	to	to	ADP
admet-510	77	9	the	the	DET
admet-510	77	10	possible	possible	ADJ
admet-510	77	11	formation	formation	NOUN
admet-510	77	12	of	of	ADP
admet-510	77	13	different	different	ADJ
admet-510	77	14	ion	ion	NOUN
admet-510	77	15	-	-	PUNCT
admet-510	77	16	pairs	pair	NOUN
admet-510	77	17	,	,	PUNCT
admet-510	77	18	depending	depend	VERB
admet-510	77	19	on	on	ADP
admet-510	77	20	the	the	DET
admet-510	77	21	experimental	experimental	ADJ
admet-510	77	22	conditions	condition	NOUN
admet-510	77	23	,	,	PUNCT
admet-510	77	24	or	or	CCONJ
admet-510	77	25	due	due	ADP
admet-510	77	26	to	to	ADP
admet-510	77	27	the	the	DET
admet-510	77	28	low	low	ADJ
admet-510	77	29	retention	retention	NOUN
admet-510	77	30	of	of	ADP
admet-510	77	31	fully	fully	ADV
admet-510	77	32	ionized	ionize	VERB
admet-510	77	33	acid	acid	NOUN
admet-510	77	34	species	specie	NOUN
admet-510	77	35	in	in	ADP
admet-510	77	36	the	the	DET
admet-510	77	37	meekc	meekc	ADJ
admet-510	77	38	system	system	NOUN
admet-510	77	39	(	(	PUNCT
admet-510	77	40	meaning	mean	VERB
admet-510	77	41	higher	high	ADJ
admet-510	77	42	experimental	experimental	ADJ
admet-510	77	43	errors	error	NOUN
admet-510	77	44	as	as	ADP
admet-510	77	45	the	the	DET
admet-510	77	46	magnitude	magnitude	NOUN
admet-510	77	47	of	of	ADP
admet-510	77	48	k	k	PROPN
admet-510	77	49	is	be	AUX
admet-510	77	50	smaller	small	ADJ
admet-510	77	51	than	than	ADP
admet-510	77	52	that	that	PRON
admet-510	77	53	of	of	ADP
admet-510	77	54	the	the	DET
admet-510	77	55	neutral	neutral	ADJ
admet-510	77	56	species	specie	NOUN
admet-510	77	57	)	)	PUNCT
admet-510	77	58	.	.	PUNCT
admet-510	78	1	moreover	moreover	ADV
admet-510	78	2	,	,	PUNCT
admet-510	78	3	these	these	DET
admet-510	78	4	differences	difference	NOUN
admet-510	78	5	could	could	AUX
admet-510	78	6	also	also	ADV
admet-510	78	7	be	be	AUX
admet-510	78	8	attributed	attribute	VERB
admet-510	78	9	to	to	ADP
admet-510	78	10	a	a	DET
admet-510	78	11	surface	surface	NOUN
admet-510	78	12	between	between	ADP
admet-510	78	13	the	the	DET
admet-510	78	14	aqueous	aqueous	ADJ
admet-510	78	15	and	and	CCONJ
admet-510	78	16	the	the	DET
admet-510	78	17	lipid	lipid	NOUN
admet-510	78	18	phase	phase	NOUN
admet-510	78	19	bigger	big	ADJ
admet-510	78	20	in	in	ADP
admet-510	78	21	the	the	DET
admet-510	78	22	microemulsion	microemulsion	NOUN
admet-510	78	23	than	than	ADP
admet-510	78	24	in	in	ADP
admet-510	78	25	the	the	DET
admet-510	78	26	octanol	octanol	NOUN
admet-510	78	27	-	-	PUNCT
admet-510	78	28	water	water	NOUN
admet-510	78	29	system	system	NOUN
admet-510	78	30	.	.	PUNCT
admet-510	79	1	in	in	ADP
admet-510	79	2	this	this	DET
admet-510	79	3	way	way	NOUN
admet-510	79	4	,	,	PUNCT
admet-510	79	5	the	the	DET
admet-510	79	6	retention	retention	NOUN
admet-510	79	7	of	of	ADP
admet-510	79	8	the	the	DET
admet-510	79	9	compounds	compound	NOUN
admet-510	79	10	in	in	ADP
admet-510	79	11	meekc	meekc	NOUN
admet-510	79	12	will	will	AUX
admet-510	79	13	be	be	AUX
admet-510	79	14	larger	large	ADJ
admet-510	79	15	even	even	ADV
admet-510	79	16	if	if	SCONJ
admet-510	79	17	they	they	PRON
admet-510	79	18	are	be	AUX
admet-510	79	19	charged	charge	VERB
admet-510	79	20	as	as	SCONJ
admet-510	79	21	they	they	PRON
admet-510	79	22	will	will	AUX
admet-510	79	23	be	be	AUX
admet-510	79	24	attached	attach	VERB
admet-510	79	25	to	to	ADP
admet-510	79	26	the	the	DET
admet-510	79	27	hydrophobic	hydrophobic	NOUN
admet-510	79	28	phase	phase	NOUN
admet-510	79	29	even	even	ADV
admet-510	79	30	if	if	SCONJ
admet-510	79	31	they	they	PRON
admet-510	79	32	do	do	AUX
admet-510	79	33	not	not	PART
admet-510	79	34	partition	partition	VERB
admet-510	79	35	into	into	ADP
admet-510	79	36	it	it	PRON
admet-510	79	37	.	.	PUNCT
admet-510	80	1	further	further	ADJ
admet-510	80	2	research	research	NOUN
admet-510	80	3	is	be	AUX
admet-510	80	4	needed	need	VERB
admet-510	80	5	to	to	PART
admet-510	80	6	confirm	confirm	VERB
admet-510	80	7	these	these	DET
admet-510	80	8	differences	difference	NOUN
admet-510	80	9	,	,	PUNCT
admet-510	80	10	clarify	clarify	VERB
admet-510	80	11	them	they	PRON
admet-510	80	12	,	,	PUNCT
admet-510	80	13	and	and	CCONJ
admet-510	80	14	propose	propose	VERB
admet-510	80	15	additional	additional	ADJ
admet-510	80	16	correction	correction	NOUN
admet-510	80	17	for	for	ADP
admet-510	80	18	the	the	DET
admet-510	80	19	ionized	ionized	ADJ
admet-510	80	20	forms	form	NOUN
admet-510	80	21	of	of	ADP
admet-510	80	22	the	the	DET
admet-510	80	23	acidic	acidic	ADJ
admet-510	80	24	drugs	drug	NOUN
admet-510	80	25	.	.	PUNCT
admet-510	81	1	the	the	DET
admet-510	81	2	direct	direct	ADJ
admet-510	81	3	applicability	applicability	NOUN
admet-510	81	4	of	of	ADP
admet-510	81	5	the	the	DET
admet-510	81	6	method	method	NOUN
admet-510	81	7	to	to	PART
admet-510	81	8	ionizable	ionizable	ADJ
admet-510	81	9	basic	basic	ADJ
admet-510	81	10	compounds	compound	NOUN
admet-510	81	11	is	be	AUX
admet-510	81	12	doubtful	doubtful	ADJ
admet-510	81	13	because	because	SCONJ
admet-510	81	14	of	of	ADP
admet-510	81	15	the	the	DET
admet-510	81	16	possible	possible	ADJ
admet-510	81	17	ion	ion	NOUN
admet-510	81	18	-	-	PUNCT
admet-510	81	19	pair	pair	NOUN
admet-510	81	20	formation	formation	NOUN
admet-510	81	21	between	between	ADP
admet-510	81	22	the	the	DET
admet-510	81	23	protonated	protonate	VERB
admet-510	81	24	base	base	NOUN
admet-510	81	25	and	and	CCONJ
admet-510	81	26	the	the	DET
admet-510	81	27	anionic	anionic	ADJ
admet-510	81	28	surfactant	surfactant	NOUN
admet-510	81	29	.	.	PUNCT
admet-510	82	1	work	work	NOUN
admet-510	82	2	is	be	AUX
admet-510	82	3	in	in	ADP
admet-510	82	4	progress	progress	NOUN
admet-510	82	5	to	to	PART
admet-510	82	6	clarify	clarify	VERB
admet-510	82	7	this	this	DET
admet-510	82	8	point	point	NOUN
admet-510	82	9	.	.	PUNCT
admet-510	83	1	conclusions	conclusion	NOUN
admet-510	83	2	accurate	accurate	ADJ
admet-510	83	3	predictions	prediction	NOUN
admet-510	83	4	of	of	ADP
admet-510	83	5	log	log	NOUN
admet-510	83	6	do	do	AUX
admet-510	83	7	/	/	SYM
admet-510	83	8	w	w	NOUN
admet-510	83	9	have	have	AUX
admet-510	83	10	been	be	AUX
admet-510	83	11	obtained	obtain	VERB
admet-510	83	12	for	for	ADP
admet-510	83	13	naproxen	naproxen	NOUN
admet-510	83	14	at	at	ADP
admet-510	83	15	different	different	ADJ
admet-510	83	16	degrees	degree	NOUN
admet-510	83	17	of	of	ADP
admet-510	83	18	ionization	ionization	NOUN
admet-510	83	19	using	use	VERB
admet-510	83	20	the	the	DET
admet-510	83	21	meekc	meekc	ADJ
admet-510	83	22	system	system	NOUN
admet-510	83	23	presented	present	VERB
admet-510	83	24	in	in	ADP
admet-510	83	25	this	this	DET
admet-510	83	26	work	work	NOUN
admet-510	83	27	.	.	PUNCT
admet-510	84	1	at	at	ADP
admet-510	84	2	those	those	DET
admet-510	84	3	ph	ph	ADJ
admet-510	84	4	values	value	NOUN
admet-510	84	5	where	where	SCONJ
admet-510	84	6	the	the	DET
admet-510	84	7	compound	compound	NOUN
admet-510	84	8	is	be	AUX
admet-510	84	9	in	in	ADP
admet-510	84	10	its	its	PRON
admet-510	84	11	neutral	neutral	ADJ
admet-510	84	12	form	form	NOUN
admet-510	84	13	or	or	CCONJ
admet-510	84	14	only	only	ADV
admet-510	84	15	partially	partially	ADV
admet-510	84	16	ionized	ionize	VERB
admet-510	84	17	,	,	PUNCT
admet-510	84	18	the	the	DET
admet-510	84	19	error	error	NOUN
admet-510	84	20	obtained	obtain	VERB
admet-510	84	21	is	be	AUX
admet-510	84	22	in	in	ADP
admet-510	84	23	the	the	DET
admet-510	84	24	order	order	NOUN
admet-510	84	25	of	of	ADP
admet-510	84	26	the	the	DET
admet-510	84	27	error	error	NOUN
admet-510	84	28	obtained	obtain	VERB
admet-510	84	29	for	for	ADP
admet-510	84	30	the	the	DET
admet-510	84	31	estimation	estimation	NOUN
admet-510	84	32	of	of	ADP
admet-510	84	33	the	the	DET
admet-510	84	34	log	log	NOUN
admet-510	84	35	po	po	PROPN
admet-510	84	36	/	/	SYM
admet-510	84	37	w	w	NOUN
admet-510	84	38	of	of	ADP
admet-510	84	39	neutral	neutral	ADJ
admet-510	84	40	compounds	compound	NOUN
admet-510	84	41	and	and	CCONJ
admet-510	84	42	the	the	DET
admet-510	84	43	one	one	NUM
admet-510	84	44	of	of	ADP
admet-510	84	45	experimental	experimental	ADJ
admet-510	84	46	determinations	determination	NOUN
admet-510	84	47	.	.	PUNCT
admet-510	85	1	only	only	ADV
admet-510	85	2	at	at	ADP
admet-510	85	3	very	very	ADV
admet-510	85	4	high	high	ADJ
admet-510	85	5	ionization	ionization	NOUN
admet-510	85	6	degrees	degree	NOUN
admet-510	85	7	(	(	PUNCT
admet-510	85	8	>	>	SYM
admet-510	85	9	99.5	99.5	NUM
admet-510	85	10	%	%	NOUN
admet-510	85	11	)	)	PUNCT
admet-510	85	12	an	an	DET
admet-510	85	13	overestimation	overestimation	NOUN
admet-510	85	14	of	of	ADP
admet-510	85	15	the	the	DET
admet-510	85	16	log	log	NOUN
admet-510	85	17	do	do	AUX
admet-510	85	18	/	/	SYM
admet-510	85	19	w	w	PROPN
admet-510	85	20	is	be	AUX
admet-510	85	21	observed	observe	VERB
admet-510	85	22	.	.	PUNCT
admet-510	86	1	this	this	DET
admet-510	86	2	work	work	NOUN
admet-510	86	3	shows	show	VERB
admet-510	86	4	that	that	SCONJ
admet-510	86	5	the	the	DET
admet-510	86	6	method	method	NOUN
admet-510	86	7	based	base	VERB
admet-510	86	8	in	in	ADP
admet-510	86	9	meekc	meekc	PROPN
admet-510	86	10	is	be	AUX
admet-510	86	11	an	an	DET
admet-510	86	12	alternative	alternative	NOUN
admet-510	86	13	to	to	ADP
admet-510	86	14	the	the	DET
admet-510	86	15	classical	classical	ADJ
admet-510	86	16	shake	shake	NOUN
admet-510	86	17	-	-	PUNCT
admet-510	86	18	flask	flask	NOUN
admet-510	86	19	procedure	procedure	NOUN
admet-510	86	20	to	to	PART
admet-510	86	21	determine	determine	VERB
admet-510	86	22	log	log	NOUN
admet-510	86	23	do	do	AUX
admet-510	86	24	/	/	SYM
admet-510	86	25	w	w	NOUN
admet-510	86	26	values	value	NOUN
admet-510	86	27	for	for	ADP
admet-510	86	28	ionized	ionized	ADJ
admet-510	86	29	species	specie	NOUN
admet-510	86	30	of	of	ADP
admet-510	86	31	this	this	DET
admet-510	86	32	acid	acid	NOUN
admet-510	86	33	.	.	PUNCT
admet-510	87	1	a	a	DET
admet-510	87	2	deeper	deep	ADJ
admet-510	87	3	study	study	NOUN
admet-510	87	4	is	be	AUX
admet-510	87	5	necessary	necessary	ADJ
admet-510	87	6	to	to	PART
admet-510	87	7	check	check	VERB
admet-510	87	8	if	if	SCONJ
admet-510	87	9	this	this	DET
admet-510	87	10	behavior	behavior	NOUN
admet-510	87	11	can	can	AUX
admet-510	87	12	be	be	AUX
admet-510	87	13	extrapolated	extrapolate	VERB
admet-510	87	14	to	to	ADP
admet-510	87	15	other	other	ADJ
admet-510	87	16	compounds	compound	NOUN
admet-510	87	17	.	.	PUNCT
admet-510	88	1	acknowledgements	acknowledgement	NOUN
admet-510	88	2	:	:	PUNCT
admet-510	88	3	financial	financial	ADJ
admet-510	88	4	support	support	NOUN
admet-510	88	5	from	from	ADP
admet-510	88	6	the	the	DET
admet-510	88	7	ministerio	ministerio	PROPN
admet-510	88	8	de	de	PROPN
admet-510	88	9	economía	economía	PROPN
admet-510	88	10	y	y	PROPN
admet-510	88	11	competitividad	competitividad	PROPN
admet-510	88	12	from	from	ADP
admet-510	88	13	the	the	DET
admet-510	88	14	spanish	spanish	ADJ
admet-510	88	15	government	government	NOUN
admet-510	88	16	(	(	PUNCT
admet-510	88	17	ctq2014	ctq2014	NOUN
admet-510	88	18	-	-	PUNCT
admet-510	88	19	56253	56253	NUM
admet-510	88	20	-	-	PUNCT
admet-510	88	21	p	p	NOUN
admet-510	88	22	)	)	PUNCT
admet-510	88	23	and	and	CCONJ
admet-510	88	24	the	the	DET
admet-510	88	25	catalan	catalan	NOUN
admet-510	88	26	government	government	NOUN
admet-510	88	27	(	(	PUNCT
admet-510	88	28	2017	2017	NUM
admet-510	88	29	sgr	sgr	PROPN
admet-510	88	30	1074	1074	NUM
admet-510	88	31	)	)	PUNCT
admet-510	88	32	is	be	AUX
admet-510	88	33	acknowledged	acknowledge	VERB
admet-510	88	34	.	.	PUNCT
admet-510	89	1	afp	afp	PROPN
admet-510	89	2	wishes	wish	VERB
admet-510	89	3	to	to	PART
admet-510	89	4	thank	thank	VERB
admet-510	89	5	the	the	DET
admet-510	89	6	university	university	PROPN
admet-510	89	7	of	of	ADP
admet-510	89	8	barcelona	barcelona	PROPN
admet-510	89	9	for	for	ADP
admet-510	89	10	his	his	PRON
admet-510	89	11	phd	phd	NOUN
admet-510	89	12	fellowship	fellowship	NOUN
admet-510	89	13	.	.	PUNCT
admet-510	90	1	references	reference	NOUN
admet-510	90	2	[	[	X
admet-510	90	3	1	1	NUM
admet-510	90	4	]	]	X
admet-510	90	5	y.	y.	PROPN
admet-510	90	6	ishihama	ishihama	PROPN
admet-510	90	7	,	,	PUNCT
admet-510	90	8	y.	y.	PROPN
admet-510	90	9	oda	oda	PROPN
admet-510	90	10	,	,	PUNCT
admet-510	90	11	k.	k.	PROPN
admet-510	90	12	uchikawa	uchikawa	PROPN
admet-510	90	13	,	,	PUNCT
admet-510	90	14	n.	n.	PROPN
admet-510	90	15	asakawa	asakawa	PROPN
admet-510	90	16	.	.	PUNCT
admet-510	91	1	evaluation	evaluation	NOUN
admet-510	91	2	of	of	ADP
admet-510	91	3	solute	solute	NOUN
admet-510	91	4	hydrophobicity	hydrophobicity	NOUN
admet-510	91	5	by	by	ADP
admet-510	91	6	microemulsion	microemulsion	PROPN
admet-510	91	7	electrokinetic	electrokinetic	ADJ
admet-510	91	8	chromatography	chromatography	NOUN
admet-510	91	9	.	.	PUNCT
admet-510	92	1	analytical	analytical	ADJ
admet-510	92	2	chemistry	chemistry	NOUN
admet-510	92	3	67	67	NUM
admet-510	92	4	(	(	PUNCT
admet-510	92	5	1995	1995	NUM
admet-510	92	6	)	)	PUNCT
admet-510	92	7	1588	1588	NUM
admet-510	92	8	-	-	SYM
admet-510	92	9	1595	1595	NUM
admet-510	92	10	.	.	PUNCT
admet-510	93	1	[	[	X
admet-510	93	2	2	2	X
admet-510	93	3	]	]	X
admet-510	93	4	m.h	m.h	PROPN
admet-510	93	5	.	.	PROPN
admet-510	93	6	abraham	abraham	PROPN
admet-510	93	7	,	,	PUNCT
admet-510	93	8	c.	c.	PROPN
admet-510	93	9	treiner	treiner	NOUN
admet-510	93	10	,	,	PUNCT
admet-510	93	11	m.	m.	NOUN
admet-510	93	12	roses	rose	NOUN
admet-510	93	13	,	,	PUNCT
admet-510	93	14	c.	c.	PROPN
admet-510	93	15	rafols	rafols	PROPN
admet-510	93	16	,	,	PUNCT
admet-510	93	17	y.	y.	PROPN
admet-510	93	18	ishihama	ishihama	PROPN
admet-510	93	19	.	.	PUNCT
admet-510	94	1	linear	linear	PROPN
admet-510	94	2	free	free	ADJ
admet-510	94	3	energy	energy	NOUN
admet-510	94	4	relationship	relationship	NOUN
admet-510	94	5	analysis	analysis	NOUN
admet-510	94	6	of	of	ADP
admet-510	94	7	microemulsion	microemulsion	NOUN
admet-510	94	8	electrokinetic	electrokinetic	ADJ
admet-510	94	9	chromatographic	chromatographic	ADJ
admet-510	94	10	determination	determination	NOUN
admet-510	94	11	of	of	ADP
admet-510	94	12	lipophilicity	lipophilicity	NOUN
admet-510	94	13	.	.	PUNCT
admet-510	95	1	journal	journal	PROPN
admet-510	95	2	of	of	ADP
admet-510	95	3	chromatography	chromatography	NOUN
admet-510	95	4	a	a	DET
admet-510	95	5	752	752	NUM
admet-510	95	6	(	(	PUNCT
admet-510	95	7	1996	1996	NUM
admet-510	95	8	)	)	PUNCT
admet-510	95	9	243	243	NUM
admet-510	95	10	-	-	SYM
admet-510	95	11	249	249	NUM
admet-510	95	12	.	.	PUNCT
admet-510	96	1	[	[	X
admet-510	96	2	3	3	NUM
admet-510	96	3	]	]	PUNCT
admet-510	96	4	x.	x.	NOUN
admet-510	96	5	subirats	subirats	PROPN
admet-510	96	6	,	,	PUNCT
admet-510	96	7	h.p	h.p	PROPN
admet-510	96	8	.	.	PROPN
admet-510	96	9	yuan	yuan	PROPN
admet-510	96	10	,	,	PUNCT
admet-510	96	11	v.	v.	PROPN
admet-510	96	12	chaves	chave	NOUN
admet-510	96	13	,	,	PUNCT
admet-510	96	14	n.	n.	PROPN
admet-510	96	15	marzal	marzal	PROPN
admet-510	96	16	,	,	PUNCT
admet-510	96	17	m.	m.	NOUN
admet-510	96	18	rosés	rosés	PROPN
admet-510	96	19	.	.	PUNCT
admet-510	97	1	microemulsion	microemulsion	PROPN
admet-510	97	2	electrokinetic	electrokinetic	ADJ
admet-510	97	3	chromatography	chromatography	NOUN
admet-510	97	4	as	as	ADP
admet-510	97	5	a	a	DET
admet-510	97	6	suitable	suitable	ADJ
admet-510	97	7	tool	tool	NOUN
admet-510	97	8	for	for	ADP
admet-510	97	9	lipophilicity	lipophilicity	NOUN
admet-510	97	10	determination	determination	NOUN
admet-510	97	11	of	of	ADP
admet-510	97	12	acidic	acidic	ADJ
admet-510	97	13	,	,	PUNCT
admet-510	97	14	neutral	neutral	ADJ
admet-510	97	15	,	,	PUNCT
admet-510	97	16	and	and	CCONJ
admet-510	97	17	basic	basic	ADJ
admet-510	97	18	compounds	compound	NOUN
admet-510	97	19	.	.	PUNCT
admet-510	98	1	electrophoresis	electrophoresis	NOUN
admet-510	98	2	37	37	NUM
admet-510	98	3	(	(	PUNCT
admet-510	98	4	2016	2016	NUM
admet-510	98	5	)	)	PUNCT
admet-510	98	6	2010	2010	NUM
admet-510	98	7	-	-	SYM
admet-510	98	8	2016	2016	NUM
admet-510	98	9	.	.	PUNCT
admet-510	99	1	[	[	X
admet-510	99	2	4	4	NUM
admet-510	99	3	]	]	X
admet-510	99	4	f.	f.	PROPN
admet-510	99	5	barbato	barbato	PROPN
admet-510	99	6	,	,	PUNCT
admet-510	99	7	g.	g.	PROPN
admet-510	99	8	caliendo	caliendo	PROPN
admet-510	99	9	,	,	PUNCT
admet-510	99	10	m.i	m.i	PROPN
admet-510	99	11	.	.	PROPN
admet-510	99	12	larotonda	larotonda	PROPN
admet-510	99	13	,	,	PUNCT
admet-510	99	14	c.	c.	PROPN
admet-510	99	15	silipo	silipo	PROPN
admet-510	99	16	,	,	PUNCT
admet-510	99	17	g.	g.	PROPN
admet-510	99	18	toraldo	toraldo	PROPN
admet-510	99	19	,	,	PUNCT
admet-510	99	20	a.	a.	NOUN
admet-510	99	21	vittoria	vittoria	PROPN
admet-510	99	22	.	.	PUNCT
admet-510	100	1	distribution	distribution	NOUN
admet-510	100	2	coefficients	coefficient	NOUN
admet-510	100	3	by	by	ADP
admet-510	100	4	curve	curve	NOUN
admet-510	100	5	fitting	fitting	ADJ
admet-510	100	6	application	application	NOUN
admet-510	100	7	to	to	AUX
admet-510	100	8	ionogenic	ionogenic	VERB
admet-510	100	9	nonsteroidal	nonsteroidal	NOUN
admet-510	100	10	antiinflamatory	antiinflamatory	NOUN
admet-510	100	11	drugs	drug	NOUN
admet-510	100	12	.	.	PUNCT
admet-510	101	1	quantitative	quantitative	ADJ
admet-510	101	2	structureactivity	structureactivity	NOUN
admet-510	101	3	relationships	relationship	NOUN
admet-510	101	4	5	5	NUM
admet-510	101	5	(	(	PUNCT
admet-510	101	6	1986	1986	NUM
admet-510	101	7	)	)	PUNCT
admet-510	101	8	88	88	NUM
admet-510	101	9	-	-	SYM
admet-510	101	10	95	95	NUM
admet-510	101	11	.	.	PUNCT
admet-510	102	1	[	[	X
admet-510	102	2	5	5	X
admet-510	102	3	]	]	PUNCT
admet-510	102	4	s.	s.	PROPN
admet-510	102	5	winiwarter	winiwarter	PROPN
admet-510	102	6	,	,	PUNCT
admet-510	102	7	n.m	n.m	PROPN
admet-510	102	8	.	.	PROPN
admet-510	102	9	bonham	bonham	PROPN
admet-510	102	10	,	,	PUNCT
admet-510	102	11	f.	f.	PROPN
admet-510	102	12	ax	ax	PROPN
admet-510	102	13	,	,	PUNCT
admet-510	102	14	a.	a.	PROPN
admet-510	102	15	hallberg	hallberg	PROPN
admet-510	102	16	,	,	PUNCT
admet-510	102	17	h.	h.	PROPN
admet-510	102	18	lennernäs	lennernäs	PROPN
admet-510	102	19	,	,	PUNCT
admet-510	102	20	a.	a.	NOUN
admet-510	102	21	karlén	karlén	PROPN
admet-510	102	22	.	.	PUNCT
admet-510	103	1	correlation	correlation	NOUN
admet-510	103	2	of	of	ADP
admet-510	103	3	human	human	ADJ
admet-510	103	4	jejunal	jejunal	ADJ
admet-510	103	5	permeability	permeability	NOUN
admet-510	103	6	(	(	PUNCT
admet-510	103	7	in	in	ADP
admet-510	103	8	vivo	vivo	NOUN
admet-510	103	9	)	)	PUNCT
admet-510	103	10	of	of	ADP
admet-510	103	11	drugs	drug	NOUN
admet-510	103	12	with	with	ADP
admet-510	103	13	experimentally	experimentally	ADV
admet-510	103	14	and	and	CCONJ
admet-510	103	15	theoretically	theoretically	ADV
admet-510	103	16	derived	derive	VERB
admet-510	103	17	parameters	parameter	NOUN
admet-510	103	18	.	.	PUNCT
admet-510	104	1	a	a	DET
admet-510	104	2	multivariate	multivariate	NOUN
admet-510	104	3	data	datum	NOUN
admet-510	104	4	analysis	analysis	NOUN
admet-510	104	5	approach	approach	NOUN
admet-510	104	6	.	.	PUNCT
admet-510	105	1	journal	journal	NOUN
admet-510	105	2	of	of	ADP
admet-510	105	3	medicinal	medicinal	ADJ
admet-510	105	4	chemistry	chemistry	NOUN
admet-510	105	5	41	41	NUM
admet-510	105	6	(	(	PUNCT
admet-510	105	7	1998	1998	NUM
admet-510	105	8	)	)	PUNCT
admet-510	105	9	4939	4939	NUM
admet-510	105	10	-	-	SYM
admet-510	105	11	4949	4949	NUM
admet-510	105	12	.	.	PUNCT
admet-510	106	1	[	[	X
admet-510	106	2	6	6	NUM
admet-510	106	3	]	]	X
admet-510	106	4	m.g	m.g	PROPN
admet-510	106	5	.	.	PROPN
admet-510	106	6	khaledi	khaledi	PROPN
admet-510	106	7	,	,	PUNCT
admet-510	106	8	s.c	s.c	PROPN
admet-510	106	9	.	.	PROPN
admet-510	106	10	smith	smith	PROPN
admet-510	106	11	,	,	PUNCT
admet-510	106	12	j.k	j.k	PROPN
admet-510	106	13	.	.	PROPN
admet-510	106	14	strasters	straster	NOUN
admet-510	106	15	.	.	PUNCT
admet-510	107	1	micellar	micellar	ADJ
admet-510	107	2	electrokinetic	electrokinetic	ADJ
admet-510	107	3	capillary	capillary	ADJ
admet-510	107	4	chromatography	chromatography	NOUN
admet-510	107	5	of	of	ADP
admet-510	107	6	acidic	acidic	ADJ
admet-510	107	7	solutes	solute	NOUN
admet-510	107	8	migration	migration	NOUN
admet-510	107	9	behavior	behavior	NOUN
admet-510	107	10	and	and	CCONJ
admet-510	107	11	optimization	optimization	NOUN
admet-510	107	12	strategies	strategy	NOUN
admet-510	107	13	.	.	PUNCT
admet-510	108	1	analytical	analytical	ADJ
admet-510	108	2	chemistry	chemistry	NOUN
admet-510	108	3	63	63	NUM
admet-510	108	4	(	(	PUNCT
admet-510	108	5	1991	1991	NUM
admet-510	108	6	)	)	PUNCT
admet-510	108	7	1820	1820	NUM
admet-510	108	8	-	-	SYM
admet-510	108	9	1830	1830	NUM
admet-510	108	10	.	.	PUNCT
admet-510	109	1	[	[	X
admet-510	109	2	7	7	NUM
admet-510	109	3	]	]	PUNCT
admet-510	109	4	a.	a.	NOUN
admet-510	109	5	fernández	fernández	PROPN
admet-510	109	6	-	-	PUNCT
admet-510	109	7	pumarega	pumarega	PROPN
admet-510	109	8	,	,	PUNCT
admet-510	109	9	s.	s.	PROPN
admet-510	109	10	amézqueta	amézqueta	PROPN
admet-510	109	11	,	,	PUNCT
admet-510	109	12	e.	e.	PROPN
admet-510	109	13	fuguet	fuguet	PROPN
admet-510	109	14	,	,	PUNCT
admet-510	109	15	m.	m.	NOUN
admet-510	109	16	rosés	rosés	PROPN
admet-510	109	17	,	,	PUNCT
admet-510	109	18	manuscript	manuscript	NOUN
admet-510	109	19	in	in	ADP
admet-510	109	20	preparation	preparation	NOUN
admet-510	109	21	(	(	PUNCT
admet-510	109	22	2018	2018	NUM
admet-510	109	23	)	)	PUNCT
admet-510	109	24	.	.	PUNCT
admet-510	110	1	susana	susana	PROPN
admet-510	110	2	amézqueta	amézqueta	PROPN
admet-510	110	3	et	et	PROPN
admet-510	110	4	al	al	PROPN
admet-510	110	5	.	.	PROPN
admet-510	110	6	admet	admet	PROPN
admet-510	110	7	&	&	CCONJ
admet-510	110	8	dmpk	dmpk	PROPN
admet-510	110	9	6(1	6(1	NUM
admet-510	110	10	)	)	PUNCT
admet-510	110	11	(	(	PUNCT
admet-510	110	12	2018	2018	NUM
admet-510	110	13	)	)	PUNCT
admet-510	110	14	55	55	NUM
admet-510	110	15	-	-	SYM
admet-510	110	16	60	60	NUM
admet-510	110	17	60	60	NUM
admet-510	110	18	[	[	NOUN
admet-510	110	19	8	8	NUM
admet-510	110	20	]	]	PUNCT
admet-510	110	21	a.	a.	NOUN
admet-510	110	22	andrés	andrés	PROPN
admet-510	110	23	,	,	PUNCT
admet-510	110	24	m.	m.	NOUN
admet-510	110	25	rosés	rosés	PROPN
admet-510	110	26	,	,	PUNCT
admet-510	110	27	c.	c.	PROPN
admet-510	110	28	ràfols	ràfols	PROPN
admet-510	110	29	,	,	PUNCT
admet-510	110	30	e.	e.	PROPN
admet-510	110	31	bosch	bosch	PROPN
admet-510	110	32	,	,	PUNCT
admet-510	110	33	s.	s.	PROPN
admet-510	110	34	espinosa	espinosa	PROPN
admet-510	110	35	,	,	PUNCT
admet-510	110	36	v.	v.	ADP
admet-510	110	37	segarra	segarra	PROPN
admet-510	110	38	,	,	PUNCT
admet-510	110	39	j.m	j.m	PROPN
admet-510	110	40	.	.	PROPN
admet-510	110	41	huerta	huerta	PROPN
admet-510	110	42	.	.	PUNCT
admet-510	111	1	setup	setup	NOUN
admet-510	111	2	and	and	CCONJ
admet-510	111	3	validation	validation	NOUN
admet-510	111	4	of	of	ADP
admet-510	111	5	shake	shake	NOUN
admet-510	111	6	-	-	PUNCT
admet-510	111	7	flask	flask	NOUN
admet-510	111	8	procedures	procedure	NOUN
admet-510	111	9	for	for	ADP
admet-510	111	10	the	the	DET
admet-510	111	11	determination	determination	NOUN
admet-510	111	12	of	of	ADP
admet-510	111	13	partition	partition	NOUN
admet-510	111	14	coefficients	coefficient	NOUN
admet-510	111	15	(	(	PUNCT
admet-510	111	16	logd	logd	NOUN
admet-510	111	17	)	)	PUNCT
admet-510	111	18	from	from	ADP
admet-510	111	19	low	low	ADJ
admet-510	111	20	drug	drug	NOUN
admet-510	111	21	amounts	amount	NOUN
admet-510	111	22	.	.	PUNCT
admet-510	112	1	european	european	ADJ
admet-510	112	2	journal	journal	PROPN
admet-510	112	3	of	of	ADP
admet-510	112	4	pharmaceutical	pharmaceutical	PROPN
admet-510	112	5	sciences	science	NOUN
admet-510	112	6	76	76	NUM
admet-510	112	7	(	(	PUNCT
admet-510	112	8	2015	2015	NUM
admet-510	112	9	)	)	PUNCT
admet-510	112	10	181	181	NUM
admet-510	112	11	-	-	SYM
admet-510	112	12	191	191	NUM
admet-510	112	13	.	.	PUNCT
admet-510	113	1	[	[	X
admet-510	113	2	9	9	NUM
admet-510	113	3	]	]	PUNCT
admet-510	113	4	a.	a.	NOUN
admet-510	113	5	avdeef	avdeef	PROPN
admet-510	113	6	.	.	PUNCT
admet-510	114	1	absorption	absorption	NOUN
admet-510	114	2	and	and	CCONJ
admet-510	114	3	drug	drug	NOUN
admet-510	114	4	development	development	NOUN
admet-510	114	5	:	:	PUNCT
admet-510	114	6	solubility	solubility	NOUN
admet-510	114	7	,	,	PUNCT
admet-510	114	8	permeability	permeability	NOUN
admet-510	114	9	,	,	PUNCT
admet-510	114	10	and	and	CCONJ
admet-510	114	11	charge	charge	NOUN
admet-510	114	12	state	state	NOUN
admet-510	114	13	,	,	PUNCT
admet-510	114	14	second	second	ADJ
admet-510	114	15	edition	edition	NOUN
admet-510	114	16	,	,	PUNCT
admet-510	114	17	john	john	PROPN
admet-510	114	18	wiley	wiley	PROPN
admet-510	114	19	&	&	CCONJ
admet-510	114	20	sons	sons	PROPN
admet-510	114	21	,	,	PUNCT
admet-510	114	22	inc	inc	PROPN
admet-510	114	23	.	.	PROPN
admet-510	114	24	,	,	PUNCT
admet-510	114	25	hoboken	hoboken	PROPN
admet-510	114	26	,	,	PUNCT
admet-510	114	27	nj	nj	PROPN
admet-510	114	28	,	,	PUNCT
admet-510	114	29	usa	usa	PROPN
admet-510	114	30	,	,	PUNCT
admet-510	114	31	2012	2012	NUM
admet-510	114	32	,	,	PUNCT
admet-510	114	33	p.	p.	NOUN
admet-510	114	34	201	201	NUM
admet-510	114	35	.	.	PUNCT
admet-510	115	1	©	©	PROPN
admet-510	115	2	2018	2018	NUM
admet-510	115	3	by	by	ADP
admet-510	115	4	the	the	DET
admet-510	115	5	authors	author	NOUN
admet-510	115	6	;	;	PUNCT
admet-510	116	1	licensee	licensee	PROPN
admet-510	116	2	iapc	iapc	PROPN
admet-510	116	3	,	,	PUNCT
admet-510	116	4	zagreb	zagreb	PROPN
admet-510	116	5	,	,	PUNCT
admet-510	116	6	croatia	croatia	PROPN
admet-510	116	7	.	.	PUNCT
admet-510	117	1	this	this	DET
admet-510	117	2	article	article	NOUN
admet-510	117	3	is	be	AUX
admet-510	117	4	an	an	DET
admet-510	117	5	open	open	ADJ
admet-510	117	6	-	-	PUNCT
admet-510	117	7	access	access	NOUN
admet-510	117	8	article	article	NOUN
admet-510	117	9	distributed	distribute	VERB
admet-510	117	10	under	under	ADP
admet-510	117	11	the	the	DET
admet-510	117	12	terms	term	NOUN
admet-510	117	13	and	and	CCONJ
admet-510	117	14	conditions	condition	NOUN
admet-510	117	15	of	of	ADP
admet-510	117	16	the	the	DET
admet-510	117	17	creative	creative	ADJ
admet-510	117	18	commons	common	NOUN
admet-510	117	19	attribution	attribution	NOUN
admet-510	117	20	license(http://creativecommons.org	license(http://creativecommons.org	X
admet-510	117	21	/	/	SYM
admet-510	117	22	licenses	license	NOUN
admet-510	117	23	/	/	SYM
admet-510	117	24	by/3.0/	by/3.0/	NOUN
admet-510	117	25	)	)	PUNCT
admet-510	117	26	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN