id	sid	tid	token	lemma	pos
admet-512	1	1	estimation	estimation	NOUN
admet-512	1	2	of	of	ADP
admet-512	1	3	skin	skin	NOUN
admet-512	1	4	permeation	permeation	NOUN
admet-512	1	5	by	by	ADP
admet-512	1	6	liquid	liquid	ADJ
admet-512	1	7	chromatography	chromatography	NOUN
admet-512	1	8	doi	doi	NOUN
admet-512	1	9	:	:	PUNCT
admet-512	1	10	10.5599	10.5599	NUM
admet-512	1	11	/	/	SYM
admet-512	1	12	admet.512	admet.512	NOUN
admet-512	1	13	140	140	NUM
admet-512	1	14	admet	admet	X
admet-512	1	15	&	&	CCONJ
admet-512	1	16	dmpk	dmpk	PROPN
admet-512	1	17	6(2	6(2	NUM
admet-512	1	18	)	)	PUNCT
admet-512	1	19	(	(	PUNCT
admet-512	1	20	2018	2018	NUM
admet-512	1	21	)	)	PUNCT
admet-512	1	22	140	140	NUM
admet-512	1	23	-	-	SYM
admet-512	1	24	152	152	NUM
admet-512	1	25	;	;	PUNCT
admet-512	1	26	doi	doi	NOUN
admet-512	1	27	:	:	PUNCT
admet-512	1	28	http://dx.doi.org/10.5599/admet.512	http://dx.doi.org/10.5599/admet.512	PROPN
admet-512	1	29	open	open	ADJ
admet-512	1	30	access	access	NOUN
admet-512	1	31	:	:	PUNCT
admet-512	1	32	issn	issn	PROPN
admet-512	1	33	:	:	PUNCT
admet-512	1	34	1848	1848	NUM
admet-512	1	35	-	-	SYM
admet-512	1	36	7718	7718	NUM
admet-512	1	37	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-512	1	38	original	original	ADJ
admet-512	1	39	scientific	scientific	ADJ
admet-512	1	40	paper	paper	NOUN
admet-512	1	41	estimation	estimation	NOUN
admet-512	1	42	of	of	ADP
admet-512	1	43	skin	skin	NOUN
admet-512	1	44	permeation	permeation	NOUN
admet-512	1	45	by	by	ADP
admet-512	1	46	liquid	liquid	ADJ
admet-512	1	47	chromatography	chromatography	NOUN
admet-512	1	48	sara	sara	PROPN
admet-512	1	49	soriano	soriano	PROPN
admet-512	1	50	-	-	PUNCT
admet-512	1	51	meseguer1	meseguer1	PROPN
admet-512	1	52	,	,	PUNCT
admet-512	1	53	elisabet	elisabet	PROPN
admet-512	1	54	fuguet1,2	fuguet1,2	PROPN
admet-512	1	55	,	,	PUNCT
admet-512	1	56	adriana	adriana	PROPN
admet-512	1	57	port3	port3	PROPN
admet-512	1	58	,	,	PUNCT
admet-512	1	59	martí	martí	NOUN
admet-512	1	60	rosés1	rosés1	ADJ
admet-512	1	61	,	,	PUNCT
admet-512	1	62	*	*	SYM
admet-512	1	63	1	1	NUM
admet-512	1	64	departament	departament	ADJ
admet-512	1	65	de	de	PROPN
admet-512	1	66	química	química	PROPN
admet-512	1	67	analítica	analítica	PROPN
admet-512	1	68	i	i	PROPN
admet-512	1	69	institut	institut	PROPN
admet-512	1	70	de	de	PROPN
admet-512	1	71	biomedicina	biomedicina	PROPN
admet-512	1	72	,	,	PUNCT
admet-512	1	73	universitat	universitat	PROPN
admet-512	1	74	de	de	PROPN
admet-512	1	75	barcelona	barcelona	PROPN
admet-512	1	76	,	,	PUNCT
admet-512	1	77	martí	martí	NOUN
admet-512	1	78	i	i	PRON
admet-512	1	79	franquès	franquès	VERB
admet-512	1	80	1	1	NUM
admet-512	1	81	-	-	SYM
admet-512	1	82	11	11	NUM
admet-512	1	83	,	,	PUNCT
admet-512	1	84	08028	08028	NUM
admet-512	1	85	barcelona	barcelona	PROPN
admet-512	1	86	,	,	PUNCT
admet-512	1	87	spain	spain	PROPN
admet-512	1	88	2	2	NUM
admet-512	1	89	serra	serra	PROPN
admet-512	1	90	húnter	húnter	PROPN
admet-512	1	91	programme	programme	PROPN
admet-512	1	92	,	,	PUNCT
admet-512	1	93	generalitat	generalitat	PROPN
admet-512	1	94	de	de	PROPN
admet-512	1	95	catalunya	catalunya	PROPN
admet-512	1	96	,	,	PUNCT
admet-512	1	97	08002	08002	NUM
admet-512	1	98	barcelona	barcelona	PROPN
admet-512	1	99	,	,	PUNCT
admet-512	1	100	spain	spain	PROPN
admet-512	1	101	3	3	NUM
admet-512	1	102	esteve	esteve	PROPN
admet-512	1	103	,	,	PUNCT
admet-512	1	104	parc	parc	PROPN
admet-512	1	105	científic	científic	PROPN
admet-512	1	106	de	de	PROPN
admet-512	1	107	barcelona	barcelona	PROPN
admet-512	1	108	,	,	PUNCT
admet-512	1	109	baldiri	baldiri	PROPN
admet-512	1	110	reixac	reixac	ADJ
admet-512	1	111	4	4	NUM
admet-512	1	112	-	-	SYM
admet-512	1	113	8	8	NUM
admet-512	1	114	,	,	PUNCT
admet-512	1	115	08028	08028	NUM
admet-512	1	116	barcelona	barcelona	PROPN
admet-512	1	117	,	,	PUNCT
admet-512	1	118	spain	spain	PROPN
admet-512	1	119	*	*	PUNCT
admet-512	1	120	corresponding	correspond	VERB
admet-512	1	121	author	author	NOUN
admet-512	1	122	:	:	PUNCT
admet-512	1	123	e	e	NOUN
admet-512	1	124	-	-	NOUN
admet-512	1	125	mail	mail	NOUN
admet-512	1	126	:	:	PUNCT
admet-512	1	127	marti.roses@ub.edu	marti.roses@ub.edu	NOUN
admet-512	1	128	;	;	PUNCT
admet-512	1	129	tel	tel	PROPN
admet-512	1	130	.	.	PROPN
admet-512	1	131	:	:	PUNCT
admet-512	2	1	+34	+34	ADJ
admet-512	2	2	-	-	SYM
admet-512	2	3	934039275	934039275	NUM
admet-512	2	4	;	;	PUNCT
admet-512	2	5	fax	fax	NOUN
admet-512	2	6	:	:	PUNCT
admet-512	2	7	+34	+34	ADJ
admet-512	2	8	-	-	PUNCT
admet-512	2	9	934021233	934021233	NUM
admet-512	2	10	received	receive	VERB
admet-512	2	11	:	:	PUNCT
admet-512	2	12	february	february	PROPN
admet-512	2	13	26	26	NUM
admet-512	2	14	,	,	PUNCT
admet-512	2	15	2018	2018	NUM
admet-512	2	16	;	;	PUNCT
admet-512	2	17	revised	revise	VERB
admet-512	2	18	:	:	PUNCT
admet-512	2	19	april	april	PROPN
admet-512	2	20	24	24	NUM
admet-512	2	21	,	,	PUNCT
admet-512	2	22	2018	2018	NUM
admet-512	2	23	;	;	PUNCT
admet-512	2	24	available	available	ADJ
admet-512	2	25	online	online	ADV
admet-512	2	26	:	:	PUNCT
admet-512	2	27	may	may	AUX
admet-512	2	28	11	11	NUM
admet-512	2	29	,	,	PUNCT
admet-512	2	30	2018	2018	NUM
admet-512	2	31	abstract	abstract	ADJ
admet-512	2	32	dermal	dermal	NOUN
admet-512	2	33	absorption	absorption	NOUN
admet-512	2	34	is	be	AUX
admet-512	2	35	a	a	DET
admet-512	2	36	key	key	ADJ
admet-512	2	37	process	process	NOUN
admet-512	2	38	in	in	ADP
admet-512	2	39	the	the	DET
admet-512	2	40	drug	drug	NOUN
admet-512	2	41	delivery	delivery	NOUN
admet-512	2	42	studies	study	NOUN
admet-512	2	43	of	of	ADP
admet-512	2	44	the	the	DET
admet-512	2	45	pharmaceutical	pharmaceutical	ADJ
admet-512	2	46	and	and	CCONJ
admet-512	2	47	cosmetic	cosmetic	NOUN
admet-512	2	48	industries	industry	NOUN
admet-512	2	49	,	,	PUNCT
admet-512	2	50	as	as	ADV
admet-512	2	51	well	well	ADV
admet-512	2	52	as	as	ADP
admet-512	2	53	in	in	ADP
admet-512	2	54	the	the	DET
admet-512	2	55	fields	field	NOUN
admet-512	2	56	of	of	ADP
admet-512	2	57	dermal	dermal	ADJ
admet-512	2	58	toxicology	toxicology	NOUN
admet-512	2	59	,	,	PUNCT
admet-512	2	60	risk	risk	NOUN
admet-512	2	61	assessment	assessment	NOUN
admet-512	2	62	,	,	PUNCT
admet-512	2	63	and	and	CCONJ
admet-512	2	64	the	the	DET
admet-512	2	65	exposure	exposure	NOUN
admet-512	2	66	of	of	ADP
admet-512	2	67	environmental	environmental	ADJ
admet-512	2	68	pollutants	pollutant	NOUN
admet-512	2	69	.	.	PUNCT
admet-512	3	1	this	this	DET
admet-512	3	2	process	process	NOUN
admet-512	3	3	is	be	AUX
admet-512	3	4	typically	typically	ADV
admet-512	3	5	described	describe	VERB
admet-512	3	6	by	by	ADP
admet-512	3	7	the	the	DET
admet-512	3	8	skin	skin	NOUN
admet-512	3	9	-	-	PUNCT
admet-512	3	10	water	water	NOUN
admet-512	3	11	permeability	permeability	NOUN
admet-512	3	12	coefficient	coefficient	NOUN
admet-512	3	13	.	.	PUNCT
admet-512	4	1	however	however	ADV
admet-512	4	2	,	,	PUNCT
admet-512	4	3	in	in	ADP
admet-512	4	4	vivo	vivo	ADJ
admet-512	4	5	determination	determination	NOUN
admet-512	4	6	is	be	AUX
admet-512	4	7	laborious	laborious	ADJ
admet-512	4	8	and	and	CCONJ
admet-512	4	9	expensive	expensive	ADJ
admet-512	4	10	.	.	PUNCT
admet-512	5	1	thus	thus	ADV
admet-512	5	2	,	,	PUNCT
admet-512	5	3	in	in	ADP
admet-512	5	4	the	the	DET
admet-512	5	5	last	last	ADJ
admet-512	5	6	few	few	ADJ
admet-512	5	7	years	year	NOUN
admet-512	5	8	,	,	PUNCT
admet-512	5	9	the	the	DET
admet-512	5	10	development	development	NOUN
admet-512	5	11	of	of	ADP
admet-512	5	12	prediction	prediction	NOUN
admet-512	5	13	models	model	NOUN
admet-512	5	14	from	from	ADP
admet-512	5	15	structure	structure	NOUN
admet-512	5	16	descriptors	descriptor	NOUN
admet-512	5	17	or	or	CCONJ
admet-512	5	18	subrogation	subrogation	NOUN
admet-512	5	19	through	through	ADP
admet-512	5	20	physico	physico	NOUN
admet-512	5	21	-	-	PUNCT
admet-512	5	22	chemical	chemical	NOUN
admet-512	5	23	measurements	measurement	NOUN
admet-512	5	24	has	have	AUX
admet-512	5	25	gained	gain	VERB
admet-512	5	26	interest	interest	NOUN
admet-512	5	27	.	.	PUNCT
admet-512	6	1	in	in	ADP
admet-512	6	2	the	the	DET
admet-512	6	3	present	present	ADJ
admet-512	6	4	work	work	NOUN
admet-512	6	5	,	,	PUNCT
admet-512	6	6	a	a	DET
admet-512	6	7	previous	previous	ADJ
admet-512	6	8	subrogation	subrogation	NOUN
admet-512	6	9	model	model	NOUN
admet-512	6	10	based	base	VERB
admet-512	6	11	on	on	ADP
admet-512	6	12	the	the	DET
admet-512	6	13	chromatographic	chromatographic	ADJ
admet-512	6	14	retention	retention	NOUN
admet-512	6	15	on	on	ADP
admet-512	6	16	a	a	DET
admet-512	6	17	common	common	ADJ
admet-512	6	18	c18	c18	NOUN
admet-512	6	19	column	column	NOUN
admet-512	6	20	has	have	AUX
admet-512	6	21	been	be	AUX
admet-512	6	22	tested	test	VERB
admet-512	6	23	for	for	ADP
admet-512	6	24	a	a	DET
admet-512	6	25	wide	wide	ADJ
admet-512	6	26	set	set	NOUN
admet-512	6	27	of	of	ADP
admet-512	6	28	drugs	drug	NOUN
admet-512	6	29	with	with	ADP
admet-512	6	30	very	very	ADV
admet-512	6	31	different	different	ADJ
admet-512	6	32	chemical	chemical	NOUN
admet-512	6	33	nature	nature	NOUN
admet-512	6	34	and	and	CCONJ
admet-512	6	35	having	have	VERB
admet-512	6	36	a	a	DET
admet-512	6	37	wide	wide	ADJ
admet-512	6	38	range	range	NOUN
admet-512	6	39	of	of	ADP
admet-512	6	40	permeability	permeability	NOUN
admet-512	6	41	values	value	NOUN
admet-512	6	42	.	.	PUNCT
admet-512	7	1	a	a	DET
admet-512	7	2	total	total	NOUN
admet-512	7	3	of	of	ADP
admet-512	7	4	65	65	NUM
admet-512	7	5	compounds	compound	NOUN
admet-512	7	6	have	have	AUX
admet-512	7	7	been	be	AUX
admet-512	7	8	used	use	VERB
admet-512	7	9	to	to	PART
admet-512	7	10	establish	establish	VERB
admet-512	7	11	the	the	DET
admet-512	7	12	correlation	correlation	NOUN
admet-512	7	13	between	between	ADP
admet-512	7	14	skin	skin	NOUN
admet-512	7	15	permeation	permeation	NOUN
admet-512	7	16	and	and	CCONJ
admet-512	7	17	the	the	DET
admet-512	7	18	hplc	hplc	NOUN
admet-512	7	19	retention	retention	NOUN
admet-512	7	20	,	,	PUNCT
admet-512	7	21	corrected	correct	VERB
admet-512	7	22	by	by	ADP
admet-512	7	23	the	the	DET
admet-512	7	24	mcgowan	mcgowan	PROPN
admet-512	7	25	volume	volume	NOUN
admet-512	7	26	of	of	ADP
admet-512	7	27	the	the	DET
admet-512	7	28	drug	drug	NOUN
admet-512	7	29	.	.	PUNCT
admet-512	8	1	afterwards	afterwards	ADV
admet-512	8	2	it	it	PRON
admet-512	8	3	was	be	AUX
admet-512	8	4	successfully	successfully	ADV
admet-512	8	5	validated	validate	VERB
admet-512	8	6	in	in	ADP
admet-512	8	7	terms	term	NOUN
admet-512	8	8	of	of	ADP
admet-512	8	9	robustness	robustness	NOUN
admet-512	8	10	and	and	CCONJ
admet-512	8	11	prediction	prediction	NOUN
admet-512	8	12	ability	ability	NOUN
admet-512	8	13	.	.	PUNCT
admet-512	9	1	finally	finally	ADV
admet-512	9	2	,	,	PUNCT
admet-512	9	3	the	the	DET
admet-512	9	4	permeability	permeability	NOUN
admet-512	9	5	coefficient	coefficient	NOUN
admet-512	9	6	was	be	AUX
admet-512	9	7	estimated	estimate	VERB
admet-512	9	8	for	for	ADP
admet-512	9	9	a	a	DET
admet-512	9	10	set	set	NOUN
admet-512	9	11	of	of	ADP
admet-512	9	12	29	29	NUM
admet-512	9	13	new	new	ADJ
admet-512	9	14	drugs	drug	NOUN
admet-512	9	15	,	,	PUNCT
admet-512	9	16	and	and	CCONJ
admet-512	9	17	results	result	NOUN
admet-512	9	18	compared	compare	VERB
admet-512	9	19	to	to	ADP
admet-512	9	20	the	the	DET
admet-512	9	21	ones	one	NOUN
admet-512	9	22	obtained	obtain	VERB
admet-512	9	23	by	by	ADP
admet-512	9	24	other	other	ADJ
admet-512	9	25	estimation	estimation	NOUN
admet-512	9	26	methods	method	NOUN
admet-512	9	27	,	,	PUNCT
admet-512	9	28	as	as	ADV
admet-512	9	29	well	well	ADV
admet-512	9	30	as	as	ADP
admet-512	9	31	the	the	DET
admet-512	9	32	available	available	ADJ
admet-512	9	33	in	in	ADP
admet-512	9	34	vitro	vitro	X
admet-512	9	35	measured	measure	VERB
admet-512	9	36	values	value	NOUN
admet-512	9	37	,	,	PUNCT
admet-512	9	38	with	with	ADP
admet-512	9	39	very	very	ADV
admet-512	9	40	good	good	ADJ
admet-512	9	41	agreement	agreement	NOUN
admet-512	9	42	.	.	PUNCT
admet-512	10	1	keywords	keyword	NOUN
admet-512	10	2	dermal	dermal	VERB
admet-512	10	3	absorption	absorption	NOUN
admet-512	10	4	;	;	PUNCT
admet-512	10	5	high	high	ADJ
admet-512	10	6	-	-	PUNCT
admet-512	10	7	performance	performance	NOUN
admet-512	10	8	liquid	liquid	ADJ
admet-512	10	9	chromatography	chromatography	NOUN
admet-512	10	10	;	;	PUNCT
admet-512	10	11	estimation	estimation	NOUN
admet-512	10	12	;	;	PUNCT
admet-512	10	13	skin	skin	NOUN
admet-512	10	14	permeation	permeation	NOUN
admet-512	10	15	introduction	introduction	NOUN
admet-512	10	16	the	the	DET
admet-512	10	17	skin	skin	NOUN
admet-512	10	18	is	be	AUX
admet-512	10	19	the	the	DET
admet-512	10	20	largest	large	ADJ
admet-512	10	21	organ	organ	NOUN
admet-512	10	22	of	of	ADP
admet-512	10	23	the	the	DET
admet-512	10	24	body	body	NOUN
admet-512	10	25	,	,	PUNCT
admet-512	10	26	covering	cover	VERB
admet-512	10	27	about	about	ADP
admet-512	10	28	1.7	1.7	NUM
admet-512	10	29	m2	m2	NOUN
admet-512	10	30	and	and	CCONJ
admet-512	10	31	comprising	comprise	VERB
admet-512	10	32	approximately	approximately	ADV
admet-512	10	33	10	10	NUM
admet-512	10	34	%	%	NOUN
admet-512	10	35	of	of	ADP
admet-512	10	36	the	the	DET
admet-512	10	37	total	total	ADJ
admet-512	10	38	body	body	NOUN
admet-512	10	39	mass	mass	NOUN
admet-512	10	40	of	of	ADP
admet-512	10	41	an	an	DET
admet-512	10	42	average	average	ADJ
admet-512	10	43	person	person	NOUN
admet-512	10	44	.	.	PUNCT
admet-512	11	1	the	the	DET
admet-512	11	2	primary	primary	ADJ
admet-512	11	3	function	function	NOUN
admet-512	11	4	of	of	ADP
admet-512	11	5	the	the	DET
admet-512	11	6	skin	skin	NOUN
admet-512	11	7	is	be	AUX
admet-512	11	8	to	to	PART
admet-512	11	9	provide	provide	VERB
admet-512	11	10	a	a	DET
admet-512	11	11	barrier	barrier	NOUN
admet-512	11	12	between	between	ADP
admet-512	11	13	the	the	DET
admet-512	11	14	body	body	NOUN
admet-512	11	15	and	and	CCONJ
admet-512	11	16	the	the	DET
admet-512	11	17	external	external	ADJ
admet-512	11	18	environment	environment	NOUN
admet-512	11	19	(	(	PUNCT
admet-512	11	20	ultraviolet	ultraviolet	ADJ
admet-512	11	21	radiation	radiation	NOUN
admet-512	11	22	,	,	PUNCT
admet-512	11	23	chemicals	chemical	NOUN
admet-512	11	24	,	,	PUNCT
admet-512	11	25	allergens	allergen	NOUN
admet-512	11	26	and	and	CCONJ
admet-512	11	27	microorganisms	microorganism	NOUN
admet-512	11	28	,	,	PUNCT
admet-512	11	29	and	and	CCONJ
admet-512	11	30	the	the	DET
admet-512	11	31	loss	loss	NOUN
admet-512	11	32	of	of	ADP
admet-512	11	33	moisture	moisture	NOUN
admet-512	11	34	and	and	CCONJ
admet-512	11	35	body	body	NOUN
admet-512	11	36	nutrients	nutrient	NOUN
admet-512	11	37	)	)	PUNCT
admet-512	11	38	.	.	PUNCT
admet-512	12	1	although	although	SCONJ
admet-512	12	2	the	the	DET
admet-512	12	3	skin	skin	NOUN
admet-512	12	4	presents	present	VERB
admet-512	12	5	a	a	DET
admet-512	12	6	barrier	barrier	NOUN
admet-512	12	7	to	to	ADP
admet-512	12	8	the	the	DET
admet-512	12	9	permeation	permeation	NOUN
admet-512	12	10	of	of	ADP
admet-512	12	11	most	most	ADJ
admet-512	12	12	compounds	compound	NOUN
admet-512	12	13	,	,	PUNCT
admet-512	12	14	it	it	PRON
admet-512	12	15	provides	provide	VERB
admet-512	12	16	an	an	DET
admet-512	12	17	ideal	ideal	ADJ
admet-512	12	18	site	site	NOUN
admet-512	12	19	for	for	ADP
admet-512	12	20	the	the	DET
admet-512	12	21	administration	administration	NOUN
admet-512	12	22	of	of	ADP
admet-512	12	23	therapeutic	therapeutic	ADJ
admet-512	12	24	compounds	compound	NOUN
admet-512	12	25	for	for	ADP
admet-512	12	26	local	local	ADJ
admet-512	12	27	and	and	CCONJ
admet-512	12	28	systemic	systemic	ADJ
admet-512	12	29	effects	effect	NOUN
admet-512	12	30	[	[	X
admet-512	12	31	1	1	NUM
admet-512	12	32	]	]	PUNCT
admet-512	12	33	.	.	PUNCT
admet-512	13	1	dermal	dermal	ADJ
admet-512	13	2	absorption	absorption	NOUN
admet-512	13	3	is	be	AUX
admet-512	13	4	a	a	DET
admet-512	13	5	global	global	ADJ
admet-512	13	6	term	term	NOUN
admet-512	13	7	that	that	PRON
admet-512	13	8	refers	refer	VERB
admet-512	13	9	to	to	ADP
admet-512	13	10	the	the	DET
admet-512	13	11	transport	transport	NOUN
admet-512	13	12	of	of	ADP
admet-512	13	13	a	a	DET
admet-512	13	14	chemical	chemical	NOUN
admet-512	13	15	from	from	ADP
admet-512	13	16	the	the	DET
admet-512	13	17	outer	outer	ADJ
admet-512	13	18	surface	surface	NOUN
admet-512	13	19	of	of	ADP
admet-512	13	20	the	the	DET
admet-512	13	21	skin	skin	NOUN
admet-512	13	22	into	into	ADP
admet-512	13	23	the	the	DET
admet-512	13	24	skin	skin	NOUN
admet-512	13	25	and	and	CCONJ
admet-512	13	26	the	the	DET
admet-512	13	27	systemic	systemic	ADJ
admet-512	13	28	circulation	circulation	NOUN
admet-512	13	29	.	.	PUNCT
admet-512	14	1	the	the	DET
admet-512	14	2	outermost	outermost	ADJ
admet-512	14	3	layer	layer	NOUN
admet-512	14	4	of	of	ADP
admet-512	14	5	the	the	DET
admet-512	14	6	skin	skin	NOUN
admet-512	14	7	,	,	PUNCT
admet-512	14	8	the	the	DET
admet-512	14	9	stratum	stratum	NOUN
admet-512	14	10	corneum	corneum	NOUN
admet-512	14	11	,	,	PUNCT
admet-512	14	12	controls	control	VERB
admet-512	14	13	the	the	DET
admet-512	14	14	dermal	dermal	ADJ
admet-512	14	15	absorption	absorption	NOUN
admet-512	14	16	process	process	NOUN
admet-512	14	17	,	,	PUNCT
admet-512	14	18	since	since	SCONJ
admet-512	14	19	substances	substance	NOUN
admet-512	14	20	must	must	AUX
admet-512	14	21	initially	initially	ADV
admet-512	14	22	permeate	permeate	VERB
admet-512	14	23	through	through	ADP
admet-512	14	24	it	it	PRON
admet-512	14	25	to	to	PART
admet-512	14	26	be	be	AUX
admet-512	14	27	absorbed	absorb	VERB
admet-512	14	28	into	into	ADP
admet-512	14	29	the	the	DET
admet-512	14	30	body	body	NOUN
admet-512	14	31	.	.	PUNCT
admet-512	15	1	hence	hence	ADV
admet-512	15	2	stratum	stratum	PROPN
admet-512	15	3	corneum	corneum	NOUN
admet-512	15	4	is	be	AUX
admet-512	15	5	considered	consider	VERB
admet-512	15	6	the	the	DET
admet-512	15	7	rate	rate	NOUN
admet-512	15	8	-	-	PUNCT
admet-512	15	9	determining	determine	VERB
admet-512	15	10	barrier	barrier	NOUN
admet-512	15	11	and	and	CCONJ
admet-512	15	12	the	the	DET
admet-512	15	13	absorption	absorption	NOUN
admet-512	15	14	process	process	NOUN
admet-512	15	15	can	can	AUX
admet-512	15	16	only	only	ADV
admet-512	15	17	occur	occur	VERB
admet-512	15	18	by	by	ADP
admet-512	15	19	passive	passive	ADJ
admet-512	15	20	diffusion	diffusion	NOUN
admet-512	15	21	since	since	SCONJ
admet-512	15	22	skin	skin	NOUN
admet-512	15	23	does	do	AUX
admet-512	15	24	not	not	PART
admet-512	15	25	have	have	VERB
admet-512	15	26	any	any	DET
admet-512	15	27	active	active	ADJ
admet-512	15	28	transport	transport	NOUN
admet-512	15	29	mechanism	mechanism	NOUN
admet-512	15	30	[	[	X
admet-512	15	31	2,3	2,3	NUM
admet-512	15	32	]	]	PUNCT
admet-512	15	33	.	.	PUNCT
admet-512	16	1	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-512	16	2	admet	admet	PROPN
admet-512	16	3	&	&	CCONJ
admet-512	16	4	dmpk	dmpk	PROPN
admet-512	16	5	6(2	6(2	NUM
admet-512	16	6	)	)	PUNCT
admet-512	16	7	(	(	PUNCT
admet-512	16	8	2018	2018	NUM
admet-512	16	9	)	)	PUNCT
admet-512	16	10	140	140	NUM
admet-512	16	11	-	-	SYM
admet-512	16	12	152	152	NUM
admet-512	16	13	estimation	estimation	NOUN
admet-512	16	14	of	of	ADP
admet-512	16	15	skin	skin	NOUN
admet-512	16	16	permeation	permeation	NOUN
admet-512	16	17	by	by	ADP
admet-512	16	18	liquid	liquid	ADJ
admet-512	16	19	chromatography	chromatography	NOUN
admet-512	16	20	doi	doi	NOUN
admet-512	16	21	:	:	PUNCT
admet-512	16	22	10.5599	10.5599	NUM
admet-512	16	23	/	/	SYM
admet-512	16	24	admet.512	admet.512	NOUN
admet-512	16	25	141	141	NUM
admet-512	16	26	dermal	dermal	NOUN
admet-512	16	27	absorption	absorption	NOUN
admet-512	16	28	is	be	AUX
admet-512	16	29	a	a	DET
admet-512	16	30	key	key	ADJ
admet-512	16	31	process	process	NOUN
admet-512	16	32	in	in	ADP
admet-512	16	33	the	the	DET
admet-512	16	34	drug	drug	NOUN
admet-512	16	35	delivery	delivery	NOUN
admet-512	16	36	studies	study	NOUN
admet-512	16	37	of	of	ADP
admet-512	16	38	the	the	DET
admet-512	16	39	pharmaceutical	pharmaceutical	NOUN
admet-512	16	40	and	and	CCONJ
admet-512	16	41	the	the	DET
admet-512	16	42	cosmetic	cosmetic	ADJ
admet-512	16	43	industries	industry	NOUN
admet-512	16	44	as	as	ADV
admet-512	16	45	well	well	ADV
admet-512	16	46	as	as	ADP
admet-512	16	47	in	in	ADP
admet-512	16	48	the	the	DET
admet-512	16	49	fields	field	NOUN
admet-512	16	50	of	of	ADP
admet-512	16	51	dermal	dermal	ADJ
admet-512	16	52	toxicology	toxicology	NOUN
admet-512	16	53	,	,	PUNCT
admet-512	16	54	risk	risk	NOUN
admet-512	16	55	assessment	assessment	NOUN
admet-512	16	56	and	and	CCONJ
admet-512	16	57	the	the	DET
admet-512	16	58	exposure	exposure	NOUN
admet-512	16	59	to	to	ADP
admet-512	16	60	environmental	environmental	ADJ
admet-512	16	61	pollutants	pollutant	NOUN
admet-512	16	62	.	.	PUNCT
admet-512	17	1	it	it	PRON
admet-512	17	2	is	be	AUX
admet-512	17	3	typically	typically	ADV
admet-512	17	4	described	describe	VERB
admet-512	17	5	by	by	ADP
admet-512	17	6	the	the	DET
admet-512	17	7	skin	skin	NOUN
admet-512	17	8	-	-	PUNCT
admet-512	17	9	water	water	NOUN
admet-512	17	10	permeability	permeability	NOUN
admet-512	17	11	coefficient	coefficient	NOUN
admet-512	17	12	(	(	PUNCT
admet-512	17	13	kp	kp	INTJ
admet-512	17	14	,	,	PUNCT
admet-512	17	15	units	unit	NOUN
admet-512	17	16	in	in	ADP
admet-512	17	17	cm	cm	PROPN
admet-512	17	18	s	s	PART
admet-512	17	19	-1	-1	PUNCT
admet-512	17	20	)	)	PUNCT
admet-512	17	21	and	and	CCONJ
admet-512	17	22	can	can	AUX
admet-512	17	23	be	be	AUX
admet-512	17	24	determined	determine	VERB
admet-512	17	25	using	use	VERB
admet-512	17	26	experimental	experimental	ADJ
admet-512	17	27	techniques	technique	NOUN
admet-512	17	28	,	,	PUNCT
admet-512	17	29	both	both	CCONJ
admet-512	17	30	in	in	ADP
admet-512	17	31	vivo	vivo	NOUN
admet-512	17	32	and	and	CCONJ
admet-512	17	33	in	in	ADP
admet-512	17	34	vitro	vitro	X
admet-512	17	35	[	[	X
admet-512	17	36	3	3	NUM
admet-512	17	37	]	]	PUNCT
admet-512	17	38	.	.	PUNCT
admet-512	18	1	however	however	ADV
admet-512	18	2	,	,	PUNCT
admet-512	18	3	these	these	DET
admet-512	18	4	methods	method	NOUN
admet-512	18	5	are	be	AUX
admet-512	18	6	usually	usually	ADV
admet-512	18	7	laborious	laborious	ADJ
admet-512	18	8	,	,	PUNCT
admet-512	18	9	costly	costly	ADJ
admet-512	18	10	and	and	CCONJ
admet-512	18	11	ethically	ethically	ADV
admet-512	18	12	questionable	questionable	ADJ
admet-512	18	13	.	.	PUNCT
admet-512	19	1	for	for	ADP
admet-512	19	2	this	this	DET
admet-512	19	3	reason	reason	NOUN
admet-512	19	4	,	,	PUNCT
admet-512	19	5	there	there	PRON
admet-512	19	6	is	be	VERB
admet-512	19	7	a	a	DET
admet-512	19	8	need	need	NOUN
admet-512	19	9	for	for	ADP
admet-512	19	10	finding	find	VERB
admet-512	19	11	methods	method	NOUN
admet-512	19	12	capable	capable	ADJ
admet-512	19	13	of	of	ADP
admet-512	19	14	predicting	predict	VERB
admet-512	19	15	kp	kp	PROPN
admet-512	19	16	values	value	NOUN
admet-512	19	17	in	in	ADP
admet-512	19	18	a	a	DET
admet-512	19	19	simple	simple	ADJ
admet-512	19	20	,	,	PUNCT
admet-512	19	21	economic	economic	ADJ
admet-512	19	22	,	,	PUNCT
admet-512	19	23	fast	fast	ADJ
admet-512	19	24	and	and	CCONJ
admet-512	19	25	ethical	ethical	ADJ
admet-512	19	26	way	way	NOUN
admet-512	19	27	.	.	PUNCT
admet-512	20	1	to	to	PART
admet-512	20	2	predict	predict	VERB
admet-512	20	3	skin	skin	NOUN
admet-512	20	4	-	-	PUNCT
admet-512	20	5	water	water	NOUN
admet-512	20	6	permeability	permeability	NOUN
admet-512	20	7	coefficients	coefficient	NOUN
admet-512	20	8	and	and	CCONJ
admet-512	20	9	thus	thus	ADV
admet-512	20	10	reduce	reduce	VERB
admet-512	20	11	the	the	DET
admet-512	20	12	number	number	NOUN
admet-512	20	13	of	of	ADP
admet-512	20	14	in	in	ADP
admet-512	20	15	vivo	vivo	NOUN
admet-512	20	16	and	and	CCONJ
admet-512	20	17	in	in	ADP
admet-512	20	18	vitro	vitro	X
admet-512	20	19	assays	assay	NOUN
admet-512	20	20	,	,	PUNCT
admet-512	20	21	two	two	NUM
admet-512	20	22	types	type	NOUN
admet-512	20	23	of	of	ADP
admet-512	20	24	models	model	NOUN
admet-512	20	25	,	,	PUNCT
admet-512	20	26	empirical	empirical	ADJ
admet-512	20	27	and	and	CCONJ
admet-512	20	28	theoretical	theoretical	ADJ
admet-512	20	29	,	,	PUNCT
admet-512	20	30	can	can	AUX
admet-512	20	31	be	be	AUX
admet-512	20	32	developed	develop	VERB
admet-512	20	33	.	.	PUNCT
admet-512	21	1	empirical	empirical	ADJ
admet-512	21	2	models	model	NOUN
admet-512	21	3	relate	relate	VERB
admet-512	21	4	the	the	DET
admet-512	21	5	kp	kp	PROPN
admet-512	21	6	values	value	NOUN
admet-512	21	7	of	of	ADP
admet-512	21	8	compounds	compound	NOUN
admet-512	21	9	to	to	ADP
admet-512	21	10	physicochemical	physicochemical	ADJ
admet-512	21	11	descriptors	descriptor	NOUN
admet-512	21	12	,	,	PUNCT
admet-512	21	13	as	as	ADP
admet-512	21	14	for	for	ADP
admet-512	21	15	example	example	NOUN
admet-512	21	16	descriptors	descriptor	NOUN
admet-512	21	17	of	of	ADP
admet-512	21	18	hydrophobicity	hydrophobicity	NOUN
admet-512	21	19	,	,	PUNCT
admet-512	21	20	polarity	polarity	NOUN
admet-512	21	21	,	,	PUNCT
admet-512	21	22	solubility	solubility	NOUN
admet-512	21	23	,	,	PUNCT
admet-512	21	24	hydrogen	hydrogen	NOUN
admet-512	21	25	bonding	bonding	NOUN
admet-512	21	26	,	,	PUNCT
admet-512	21	27	or	or	CCONJ
admet-512	21	28	size	size	NOUN
admet-512	21	29	[	[	X
admet-512	21	30	4	4	NUM
admet-512	21	31	]	]	PUNCT
admet-512	21	32	.	.	PUNCT
admet-512	22	1	in	in	ADP
admet-512	22	2	general	general	ADJ
admet-512	22	3	,	,	PUNCT
admet-512	22	4	empirical	empirical	ADJ
admet-512	22	5	models	model	NOUN
admet-512	22	6	for	for	ADP
admet-512	22	7	skin	skin	NOUN
admet-512	22	8	permeation	permeation	NOUN
admet-512	22	9	,	,	PUNCT
admet-512	22	10	as	as	SCONJ
admet-512	22	11	proposed	propose	VERB
admet-512	22	12	by	by	ADP
admet-512	22	13	patel	patel	PROPN
admet-512	22	14	et	et	PROPN
admet-512	22	15	al	al	PROPN
admet-512	22	16	.	.	PUNCT
admet-512	23	1	[	[	X
admet-512	23	2	5	5	NUM
admet-512	23	3	]	]	PUNCT
admet-512	23	4	,	,	PUNCT
admet-512	23	5	usually	usually	ADV
admet-512	23	6	reveal	reveal	VERB
admet-512	23	7	the	the	DET
admet-512	23	8	important	important	ADJ
admet-512	23	9	roles	role	NOUN
admet-512	23	10	of	of	ADP
admet-512	23	11	lipophilicity	lipophilicity	NOUN
admet-512	23	12	and	and	CCONJ
admet-512	23	13	molecular	molecular	ADJ
admet-512	23	14	size	size	NOUN
admet-512	23	15	.	.	PUNCT
admet-512	24	1	theoretical	theoretical	ADJ
admet-512	24	2	models	model	NOUN
admet-512	24	3	are	be	AUX
admet-512	24	4	mechanistic	mechanistic	ADJ
admet-512	24	5	approaches	approach	NOUN
admet-512	24	6	that	that	PRON
admet-512	24	7	attempt	attempt	VERB
admet-512	24	8	to	to	PART
admet-512	24	9	simulate	simulate	VERB
admet-512	24	10	the	the	DET
admet-512	24	11	dynamic	dynamic	ADJ
admet-512	24	12	processes	process	NOUN
admet-512	24	13	that	that	PRON
admet-512	24	14	are	be	AUX
admet-512	24	15	involved	involve	VERB
admet-512	24	16	in	in	ADP
admet-512	24	17	skin	skin	NOUN
admet-512	24	18	permeation	permeation	NOUN
admet-512	24	19	.	.	PUNCT
admet-512	25	1	they	they	PRON
admet-512	25	2	consist	consist	VERB
admet-512	25	3	of	of	ADP
admet-512	25	4	mathematical	mathematical	ADJ
admet-512	25	5	transport	transport	NOUN
admet-512	25	6	models	model	NOUN
admet-512	25	7	that	that	PRON
admet-512	25	8	relate	relate	VERB
admet-512	25	9	dermal	dermal	ADJ
admet-512	25	10	absorption	absorption	NOUN
admet-512	25	11	to	to	ADP
admet-512	25	12	parameters	parameter	NOUN
admet-512	25	13	like	like	ADP
admet-512	25	14	diffusion	diffusion	NOUN
admet-512	25	15	coefficients	coefficient	NOUN
admet-512	25	16	and	and	CCONJ
admet-512	25	17	partition	partition	NOUN
admet-512	25	18	coefficients	coefficient	NOUN
admet-512	25	19	,	,	PUNCT
admet-512	25	20	taking	take	VERB
admet-512	25	21	into	into	ADP
admet-512	25	22	account	account	NOUN
admet-512	25	23	factors	factor	NOUN
admet-512	25	24	such	such	ADJ
admet-512	25	25	as	as	ADP
admet-512	25	26	possible	possible	ADJ
admet-512	25	27	routes	route	NOUN
admet-512	25	28	of	of	ADP
admet-512	25	29	penetration	penetration	NOUN
admet-512	25	30	and	and	CCONJ
admet-512	25	31	interactions	interaction	NOUN
admet-512	25	32	between	between	ADP
admet-512	25	33	the	the	DET
admet-512	25	34	permeating	permeate	VERB
admet-512	25	35	chemicals	chemical	NOUN
admet-512	25	36	and	and	CCONJ
admet-512	25	37	the	the	DET
admet-512	25	38	skin	skin	NOUN
admet-512	25	39	constituents	constituent	NOUN
admet-512	25	40	[	[	X
admet-512	25	41	6	6	NUM
admet-512	25	42	-	-	SYM
admet-512	25	43	8	8	NUM
admet-512	25	44	]	]	PUNCT
admet-512	25	45	.	.	PUNCT
admet-512	26	1	linear	linear	ADJ
admet-512	26	2	free	free	ADJ
admet-512	26	3	-	-	PUNCT
admet-512	26	4	energy	energy	NOUN
admet-512	26	5	relationships	relationship	NOUN
admet-512	26	6	(	(	PUNCT
admet-512	26	7	lfers	lfer	NOUN
admet-512	26	8	)	)	PUNCT
admet-512	26	9	,	,	PUNCT
admet-512	26	10	a	a	DET
admet-512	26	11	particular	particular	ADJ
admet-512	26	12	type	type	NOUN
admet-512	26	13	of	of	ADP
admet-512	26	14	quantitative	quantitative	ADJ
admet-512	26	15	structure	structure	NOUN
admet-512	26	16	-	-	PUNCT
admet-512	26	17	activity	activity	NOUN
admet-512	26	18	relationship	relationship	NOUN
admet-512	26	19	(	(	PUNCT
admet-512	26	20	qsar	qsar	NOUN
admet-512	26	21	)	)	PUNCT
admet-512	26	22	,	,	PUNCT
admet-512	26	23	are	be	AUX
admet-512	26	24	widely	widely	ADV
admet-512	26	25	used	use	VERB
admet-512	26	26	to	to	PART
admet-512	26	27	characterize	characterize	VERB
admet-512	26	28	chemical	chemical	NOUN
admet-512	26	29	and	and	CCONJ
admet-512	26	30	biochemical	biochemical	ADJ
admet-512	26	31	processes	process	NOUN
admet-512	26	32	.	.	PUNCT
admet-512	27	1	lfers	lfer	NOUN
admet-512	27	2	assume	assume	VERB
admet-512	27	3	that	that	SCONJ
admet-512	27	4	the	the	DET
admet-512	27	5	free	free	ADJ
admet-512	27	6	energy	energy	NOUN
admet-512	27	7	change	change	NOUN
admet-512	27	8	associated	associate	VERB
admet-512	27	9	with	with	ADP
admet-512	27	10	the	the	DET
admet-512	27	11	property	property	NOUN
admet-512	27	12	of	of	ADP
admet-512	27	13	interest	interest	NOUN
admet-512	27	14	is	be	AUX
admet-512	27	15	linearly	linearly	ADV
admet-512	27	16	related	relate	VERB
admet-512	27	17	to	to	PART
admet-512	27	18	solute	solute	VERB
admet-512	27	19	molecular	molecular	ADJ
admet-512	27	20	descriptors	descriptor	NOUN
admet-512	27	21	.	.	PUNCT
admet-512	28	1	the	the	DET
admet-512	28	2	linear	linear	PROPN
admet-512	28	3	solvation	solvation	NOUN
admet-512	28	4	energy	energy	NOUN
admet-512	28	5	relationships	relationship	NOUN
admet-512	28	6	(	(	PUNCT
admet-512	28	7	lsers	lser	NOUN
admet-512	28	8	)	)	PUNCT
admet-512	28	9	,	,	PUNCT
admet-512	28	10	proposed	propose	VERB
admet-512	28	11	by	by	ADP
admet-512	28	12	kamlet	kamlet	PROPN
admet-512	28	13	et	et	PROPN
admet-512	28	14	al	al	PROPN
admet-512	28	15	.	.	PUNCT
admet-512	29	1	[	[	X
admet-512	29	2	9	9	NUM
admet-512	29	3	]	]	PUNCT
admet-512	29	4	,	,	PUNCT
admet-512	29	5	are	be	AUX
admet-512	29	6	based	base	VERB
admet-512	29	7	on	on	ADP
admet-512	29	8	the	the	DET
admet-512	29	9	change	change	NOUN
admet-512	29	10	of	of	ADP
admet-512	29	11	free	free	ADJ
admet-512	29	12	energy	energy	NOUN
admet-512	29	13	due	due	ADP
admet-512	29	14	to	to	ADP
admet-512	29	15	the	the	DET
admet-512	29	16	solvation	solvation	NOUN
admet-512	29	17	process	process	NOUN
admet-512	29	18	of	of	ADP
admet-512	29	19	a	a	DET
admet-512	29	20	solute	solute	NOUN
admet-512	29	21	into	into	ADP
admet-512	29	22	a	a	DET
admet-512	29	23	solvent	solvent	NOUN
admet-512	29	24	.	.	PUNCT
admet-512	30	1	among	among	ADP
admet-512	30	2	the	the	DET
admet-512	30	3	variety	variety	NOUN
admet-512	30	4	of	of	ADP
admet-512	30	5	models	model	NOUN
admet-512	30	6	based	base	VERB
admet-512	30	7	on	on	ADP
admet-512	30	8	these	these	DET
admet-512	30	9	principles	principle	NOUN
admet-512	30	10	,	,	PUNCT
admet-512	30	11	the	the	DET
admet-512	30	12	solvation	solvation	NOUN
admet-512	30	13	parameter	parameter	NOUN
admet-512	30	14	model	model	NOUN
admet-512	30	15	developed	develop	VERB
admet-512	30	16	by	by	ADP
admet-512	30	17	abraham	abraham	PROPN
admet-512	31	1	[	[	X
admet-512	31	2	10	10	NUM
admet-512	31	3	]	]	PUNCT
admet-512	31	4	is	be	AUX
admet-512	31	5	one	one	NUM
admet-512	31	6	of	of	ADP
admet-512	31	7	the	the	DET
admet-512	31	8	most	most	ADV
admet-512	31	9	widely	widely	ADV
admet-512	31	10	used	use	VERB
admet-512	31	11	in	in	ADP
admet-512	31	12	order	order	NOUN
admet-512	31	13	to	to	PART
admet-512	31	14	achieve	achieve	VERB
admet-512	31	15	a	a	DET
admet-512	31	16	better	well	ADJ
admet-512	31	17	understanding	understanding	NOUN
admet-512	31	18	of	of	ADP
admet-512	31	19	the	the	DET
admet-512	31	20	type	type	NOUN
admet-512	31	21	and	and	CCONJ
admet-512	31	22	the	the	DET
admet-512	31	23	relative	relative	ADJ
admet-512	31	24	strength	strength	NOUN
admet-512	31	25	of	of	ADP
admet-512	31	26	the	the	DET
admet-512	31	27	chemical	chemical	ADJ
admet-512	31	28	interactions	interaction	NOUN
admet-512	31	29	that	that	PRON
admet-512	31	30	control	control	VERB
admet-512	31	31	any	any	DET
admet-512	31	32	solvation	solvation	NOUN
admet-512	31	33	process	process	NOUN
admet-512	31	34	of	of	ADP
admet-512	31	35	neutral	neutral	ADJ
admet-512	31	36	compounds	compound	NOUN
admet-512	31	37	[	[	X
admet-512	31	38	11,12	11,12	NUM
admet-512	31	39	]	]	PUNCT
admet-512	31	40	.	.	PUNCT
admet-512	32	1	this	this	DET
admet-512	32	2	model	model	NOUN
admet-512	32	3	has	have	AUX
admet-512	32	4	been	be	AUX
admet-512	32	5	successfully	successfully	ADV
admet-512	32	6	applied	apply	VERB
admet-512	32	7	to	to	PART
admet-512	32	8	characterize	characterize	VERB
admet-512	32	9	many	many	ADJ
admet-512	32	10	biological	biological	ADJ
admet-512	32	11	processes	process	NOUN
admet-512	32	12	,	,	PUNCT
admet-512	32	13	including	include	VERB
admet-512	32	14	some	some	DET
admet-512	32	15	toxicological	toxicological	ADJ
admet-512	32	16	and	and	CCONJ
admet-512	32	17	environmental	environmental	ADJ
admet-512	32	18	ones	one	NOUN
admet-512	32	19	,	,	PUNCT
admet-512	32	20	as	as	ADV
admet-512	32	21	well	well	ADV
admet-512	32	22	as	as	ADP
admet-512	32	23	a	a	DET
admet-512	32	24	wide	wide	ADJ
admet-512	32	25	range	range	NOUN
admet-512	32	26	of	of	ADP
admet-512	32	27	physicochemical	physicochemical	ADJ
admet-512	32	28	processes	process	NOUN
admet-512	32	29	ruled	rule	VERB
admet-512	32	30	by	by	ADP
admet-512	32	31	the	the	DET
admet-512	32	32	passive	passive	ADJ
admet-512	32	33	transport	transport	NOUN
admet-512	32	34	of	of	ADP
admet-512	32	35	solutes	solute	NOUN
admet-512	32	36	between	between	ADP
admet-512	32	37	two	two	NUM
admet-512	32	38	phases	phase	NOUN
admet-512	32	39	.	.	PUNCT
admet-512	33	1	the	the	DET
admet-512	33	2	solvation	solvation	NOUN
admet-512	33	3	parameter	parameter	NOUN
admet-512	33	4	model	model	NOUN
admet-512	33	5	[	[	X
admet-512	33	6	10,12	10,12	NOUN
admet-512	33	7	]	]	PUNCT
admet-512	33	8	has	have	AUX
admet-512	33	9	been	be	AUX
admet-512	33	10	also	also	ADV
admet-512	33	11	applied	apply	VERB
admet-512	33	12	to	to	PART
admet-512	33	13	model	model	VERB
admet-512	33	14	the	the	DET
admet-512	33	15	human	human	ADJ
admet-512	33	16	skin	skin	NOUN
admet-512	33	17	permeation	permeation	NOUN
admet-512	33	18	process	process	NOUN
admet-512	33	19	[	[	X
admet-512	33	20	12	12	NUM
admet-512	33	21	-	-	SYM
admet-512	33	22	16	16	NUM
admet-512	33	23	]	]	PUNCT
admet-512	33	24	.	.	PUNCT
admet-512	34	1	abraham	abraham	PROPN
admet-512	34	2	and	and	CCONJ
admet-512	34	3	martins	martin	VERB
admet-512	34	4	[	[	X
admet-512	34	5	15	15	NUM
admet-512	34	6	]	]	PUNCT
admet-512	34	7	proposed	propose	VERB
admet-512	34	8	the	the	DET
admet-512	34	9	following	follow	VERB
admet-512	34	10	equation	equation	NOUN
admet-512	34	11	for	for	ADP
admet-512	34	12	characterizing	characterize	VERB
admet-512	34	13	the	the	DET
admet-512	34	14	permeation	permeation	NOUN
admet-512	34	15	of	of	ADP
admet-512	34	16	neutral	neutral	ADJ
admet-512	34	17	solutes	solute	NOUN
admet-512	34	18	from	from	ADP
admet-512	34	19	aqueous	aqueous	ADJ
admet-512	34	20	solution	solution	NOUN
admet-512	34	21	through	through	ADP
admet-512	34	22	the	the	DET
admet-512	34	23	human	human	ADJ
admet-512	34	24	skin	skin	NOUN
admet-512	34	25	,	,	PUNCT
admet-512	34	26	log	log	NOUN
admet-512	34	27	kp	kp	NOUN
admet-512	34	28	=	=	SYM
admet-512	34	29	–	–	PUNCT
admet-512	34	30	5.246	5.246	NUM
admet-512	34	31	–	–	PUNCT
admet-512	34	32	0.106e	0.106e	NUM
admet-512	34	33	–	–	PUNCT
admet-512	34	34	0.473s	0.473s	NOUN
admet-512	34	35	–	–	PUNCT
admet-512	34	36	0.473a	0.473a	ADJ
admet-512	34	37	–	–	PUNCT
admet-512	34	38	3.000b	3.000b	NUM
admet-512	34	39	+	+	CCONJ
admet-512	34	40	2.296v	2.296v	NUM
admet-512	34	41	(	(	PUNCT
admet-512	34	42	1	1	NUM
admet-512	34	43	)	)	PUNCT
admet-512	34	44	n	n	NOUN
admet-512	34	45	=	=	SYM
admet-512	34	46	119	119	NUM
admet-512	34	47	r2	r2	NOUN
admet-512	34	48	=	=	NOUN
admet-512	34	49	0.832	0.832	NUM
admet-512	34	50	sd	sd	NOUN
admet-512	34	51	=	=	NOUN
admet-512	34	52	0.461	0.461	NUM
admet-512	34	53	f=	f=	ADJ
admet-512	34	54	112	112	NUM
admet-512	34	55	this	this	DET
admet-512	34	56	equation	equation	NOUN
admet-512	34	57	was	be	AUX
admet-512	34	58	obtained	obtain	VERB
admet-512	34	59	through	through	ADP
admet-512	34	60	the	the	DET
admet-512	34	61	analysis	analysis	NOUN
admet-512	34	62	of	of	ADP
admet-512	34	63	119	119	NUM
admet-512	34	64	compounds	compound	NOUN
admet-512	34	65	of	of	ADP
admet-512	34	66	different	different	ADJ
admet-512	34	67	chemical	chemical	NOUN
admet-512	34	68	type	type	NOUN
admet-512	34	69	,	,	PUNCT
admet-512	34	70	which	which	PRON
admet-512	34	71	covered	cover	VERB
admet-512	34	72	a	a	DET
admet-512	34	73	wide	wide	ADJ
admet-512	34	74	range	range	NOUN
admet-512	34	75	of	of	ADP
admet-512	34	76	log	log	NOUN
admet-512	34	77	kp	kp	PROPN
admet-512	34	78	values	value	NOUN
admet-512	34	79	.	.	PUNCT
admet-512	35	1	e	e	X
admet-512	35	2	,	,	PUNCT
admet-512	35	3	s	s	PROPN
admet-512	35	4	,	,	PUNCT
admet-512	35	5	a	a	DET
admet-512	35	6	,	,	PUNCT
admet-512	35	7	b	b	NOUN
admet-512	35	8	,	,	PUNCT
admet-512	35	9	and	and	CCONJ
admet-512	35	10	v	v	NOUN
admet-512	35	11	are	be	AUX
admet-512	35	12	independent	independent	ADJ
admet-512	35	13	variables	variable	NOUN
admet-512	35	14	and	and	CCONJ
admet-512	35	15	are	be	AUX
admet-512	35	16	the	the	DET
admet-512	35	17	solute	solute	ADJ
admet-512	35	18	descriptors	descriptor	NOUN
admet-512	35	19	proposed	propose	VERB
admet-512	35	20	by	by	ADP
admet-512	35	21	abraham	abraham	PROPN
admet-512	35	22	:	:	PUNCT
admet-512	35	23	e	e	NOUN
admet-512	35	24	represents	represent	VERB
admet-512	35	25	the	the	DET
admet-512	35	26	excess	excess	ADJ
admet-512	35	27	molar	molar	ADJ
admet-512	35	28	refraction	refraction	NOUN
admet-512	35	29	,	,	PUNCT
admet-512	35	30	s	s	VERB
admet-512	35	31	is	be	AUX
admet-512	35	32	the	the	DET
admet-512	35	33	solute	solute	ADJ
admet-512	35	34	dipolarity	dipolarity	NOUN
admet-512	35	35	/	/	SYM
admet-512	35	36	polarizability	polarizability	NOUN
admet-512	35	37	,	,	PUNCT
admet-512	35	38	a	a	PRON
admet-512	35	39	and	and	CCONJ
admet-512	35	40	b	b	NOUN
admet-512	35	41	are	be	AUX
admet-512	35	42	the	the	DET
admet-512	35	43	solute	solute	NOUN
admet-512	35	44	’s	’s	PART
admet-512	35	45	effective	effective	ADJ
admet-512	35	46	hydrogen	hydrogen	NOUN
admet-512	35	47	-	-	PUNCT
admet-512	35	48	bond	bond	NOUN
admet-512	35	49	acidity	acidity	NOUN
admet-512	35	50	and	and	CCONJ
admet-512	35	51	hydrogen	hydrogen	NOUN
admet-512	35	52	-	-	PUNCT
admet-512	35	53	bond	bond	NOUN
admet-512	35	54	basicity	basicity	NOUN
admet-512	35	55	,	,	PUNCT
admet-512	35	56	respectively	respectively	ADV
admet-512	35	57	,	,	PUNCT
admet-512	35	58	and	and	CCONJ
admet-512	35	59	v	v	NOUN
admet-512	35	60	is	be	AUX
admet-512	35	61	the	the	DET
admet-512	35	62	mcgowan	mcgowan	PROPN
admet-512	35	63	’s	’s	PART
admet-512	35	64	solute	solute	PROPN
admet-512	35	65	volume	volume	NOUN
admet-512	35	66	.	.	PUNCT
admet-512	36	1	eq	eq	X
admet-512	36	2	.	.	NOUN
admet-512	36	3	1	1	NUM
admet-512	36	4	shows	show	VERB
admet-512	36	5	that	that	DET
admet-512	36	6	size	size	NOUN
admet-512	36	7	is	be	AUX
admet-512	36	8	the	the	DET
admet-512	36	9	only	only	ADJ
admet-512	36	10	solute	solute	ADJ
admet-512	36	11	property	property	NOUN
admet-512	36	12	that	that	PRON
admet-512	36	13	contributes	contribute	VERB
admet-512	36	14	to	to	ADP
admet-512	36	15	an	an	DET
admet-512	36	16	increase	increase	NOUN
admet-512	36	17	in	in	ADP
admet-512	36	18	skin	skin	NOUN
admet-512	36	19	permeation	permeation	NOUN
admet-512	36	20	(	(	PUNCT
admet-512	36	21	the	the	DET
admet-512	36	22	only	only	ADJ
admet-512	36	23	positive	positive	ADJ
admet-512	36	24	coefficient	coefficient	NOUN
admet-512	36	25	)	)	PUNCT
admet-512	36	26	.	.	PUNCT
admet-512	37	1	over	over	ADP
admet-512	37	2	the	the	DET
admet-512	37	3	last	last	ADJ
admet-512	37	4	few	few	ADJ
admet-512	37	5	years	year	NOUN
admet-512	37	6	,	,	PUNCT
admet-512	37	7	the	the	DET
admet-512	37	8	computational	computational	ADJ
admet-512	37	9	models	model	NOUN
admet-512	37	10	based	base	VERB
admet-512	37	11	on	on	ADP
admet-512	37	12	calculated	calculate	VERB
admet-512	37	13	descriptors	descriptor	NOUN
admet-512	37	14	[	[	X
admet-512	37	15	17	17	NUM
admet-512	37	16	-	-	SYM
admet-512	37	17	19	19	NUM
admet-512	37	18	]	]	PUNCT
admet-512	37	19	have	have	AUX
admet-512	37	20	also	also	ADV
admet-512	37	21	become	become	VERB
admet-512	37	22	very	very	ADV
admet-512	37	23	useful	useful	ADJ
admet-512	37	24	and	and	CCONJ
admet-512	37	25	powerful	powerful	ADJ
admet-512	37	26	approaches	approach	NOUN
admet-512	37	27	to	to	PART
admet-512	37	28	provide	provide	VERB
admet-512	37	29	estimations	estimation	NOUN
admet-512	37	30	of	of	ADP
admet-512	37	31	kp	kp	PROPN
admet-512	37	32	values	value	NOUN
admet-512	37	33	.	.	PUNCT
admet-512	38	1	however	however	ADV
admet-512	38	2	,	,	PUNCT
admet-512	38	3	skin	skin	NOUN
admet-512	38	4	permeation	permeation	NOUN
admet-512	38	5	models	model	NOUN
admet-512	38	6	based	base	VERB
admet-512	38	7	on	on	ADP
admet-512	38	8	experimental	experimental	ADJ
admet-512	38	9	descriptors	descriptor	NOUN
admet-512	38	10	are	be	AUX
admet-512	38	11	generally	generally	ADV
admet-512	38	12	preferred	prefer	VERB
admet-512	38	13	when	when	SCONJ
admet-512	38	14	the	the	DET
admet-512	38	15	prediction	prediction	NOUN
admet-512	38	16	of	of	ADP
admet-512	38	17	skinmarti	skinmarti	PROPN
admet-512	38	18	rosés	rosé	VERB
admet-512	38	19	et	et	PROPN
admet-512	38	20	al	al	PROPN
admet-512	38	21	admet	admet	PROPN
admet-512	38	22	&	&	CCONJ
admet-512	38	23	dmpk	dmpk	PROPN
admet-512	38	24	6(2	6(2	NUM
admet-512	38	25	)	)	PUNCT
admet-512	38	26	(	(	PUNCT
admet-512	38	27	2018	2018	NUM
admet-512	38	28	)	)	PUNCT
admet-512	38	29	140	140	NUM
admet-512	38	30	-	-	SYM
admet-512	38	31	152	152	NUM
admet-512	38	32	142	142	NUM
admet-512	38	33	water	water	NOUN
admet-512	38	34	permeability	permeability	NOUN
admet-512	38	35	of	of	ADP
admet-512	38	36	chemicals	chemical	NOUN
admet-512	38	37	requires	require	VERB
admet-512	38	38	more	more	ADJ
admet-512	38	39	accuracy	accuracy	NOUN
admet-512	38	40	and	and	CCONJ
admet-512	38	41	reliability	reliability	NOUN
admet-512	38	42	.	.	PUNCT
admet-512	39	1	in	in	ADP
admet-512	39	2	a	a	DET
admet-512	39	3	previous	previous	ADJ
admet-512	39	4	study	study	NOUN
admet-512	39	5	[	[	X
admet-512	39	6	20	20	NUM
admet-512	39	7	]	]	PUNCT
admet-512	39	8	the	the	DET
admet-512	39	9	ability	ability	NOUN
admet-512	39	10	of	of	ADP
admet-512	39	11	different	different	ADJ
admet-512	39	12	chromatographic	chromatographic	ADJ
admet-512	39	13	systems	system	NOUN
admet-512	39	14	,	,	PUNCT
admet-512	39	15	basically	basically	ADV
admet-512	39	16	liquid	liquid	ADJ
admet-512	39	17	chromatography	chromatography	NOUN
admet-512	39	18	(	(	PUNCT
admet-512	39	19	hplc	hplc	PROPN
admet-512	39	20	)	)	PUNCT
admet-512	39	21	and	and	CCONJ
admet-512	39	22	micellar	micellar	ADJ
admet-512	39	23	electrokinetic	electrokinetic	ADJ
admet-512	39	24	chromatography	chromatography	NOUN
admet-512	39	25	(	(	PUNCT
admet-512	39	26	mekc	mekc	PROPN
admet-512	39	27	)	)	PUNCT
admet-512	39	28	,	,	PUNCT
admet-512	39	29	were	be	AUX
admet-512	39	30	assessed	assess	VERB
admet-512	39	31	to	to	PART
admet-512	39	32	subrogate	subrogate	VERB
admet-512	39	33	the	the	DET
admet-512	39	34	permeation	permeation	NOUN
admet-512	39	35	of	of	ADP
admet-512	39	36	aqueous	aqueous	ADJ
admet-512	39	37	solutions	solution	NOUN
admet-512	39	38	of	of	ADP
admet-512	39	39	neutral	neutral	ADJ
admet-512	39	40	solutes	solute	NOUN
admet-512	39	41	through	through	ADP
admet-512	39	42	human	human	ADJ
admet-512	39	43	skin	skin	NOUN
admet-512	39	44	.	.	PUNCT
admet-512	40	1	it	it	PRON
admet-512	40	2	was	be	AUX
admet-512	40	3	observed	observe	VERB
admet-512	40	4	that	that	SCONJ
admet-512	40	5	the	the	DET
admet-512	40	6	correlations	correlation	NOUN
admet-512	40	7	were	be	AUX
admet-512	40	8	improved	improve	VERB
admet-512	40	9	after	after	ADP
admet-512	40	10	introducing	introduce	VERB
admet-512	40	11	the	the	DET
admet-512	40	12	calculated	calculated	ADJ
admet-512	40	13	mcgowan	mcgowan	PROPN
admet-512	40	14	solute	solute	PROPN
admet-512	40	15	’s	’s	PART
admet-512	40	16	volume	volume	NOUN
admet-512	40	17	as	as	ADP
admet-512	40	18	an	an	DET
admet-512	40	19	additional	additional	ADJ
admet-512	40	20	variable	variable	NOUN
admet-512	40	21	.	.	PUNCT
admet-512	41	1	with	with	ADP
admet-512	41	2	the	the	DET
admet-512	41	3	volume	volume	NOUN
admet-512	41	4	correction	correction	NOUN
admet-512	41	5	,	,	PUNCT
admet-512	41	6	the	the	DET
admet-512	41	7	best	good	ADJ
admet-512	41	8	subrogation	subrogation	NOUN
admet-512	41	9	was	be	AUX
admet-512	41	10	obtained	obtain	VERB
admet-512	41	11	with	with	ADP
admet-512	41	12	an	an	DET
admet-512	41	13	hplc	hplc	NOUN
admet-512	41	14	system	system	NOUN
admet-512	41	15	fitted	fit	VERB
admet-512	41	16	with	with	ADP
admet-512	41	17	a	a	DET
admet-512	41	18	c18	c18	NOUN
admet-512	41	19	column	column	NOUN
admet-512	41	20	according	accord	VERB
admet-512	41	21	to	to	ADP
admet-512	41	22	the	the	DET
admet-512	41	23	following	follow	VERB
admet-512	41	24	equation	equation	NOUN
admet-512	41	25	,	,	PUNCT
admet-512	41	26	log	log	VERB
admet-512	41	27	kp=	kp=	PROPN
admet-512	41	28	4.76(±0.18	4.76(±0.18	PROPN
admet-512	41	29	)	)	PUNCT
admet-512	42	1	+	+	CCONJ
admet-512	42	2	1.44(±0.12	1.44(±0.12	X
admet-512	42	3	)	)	PUNCT
admet-512	42	4	log	log	NOUN
admet-512	42	5	k	k	PROPN
admet-512	42	6	1.16(±0.10	1.16(±0.10	NUM
admet-512	42	7	)	)	PUNCT
admet-512	42	8	v	v	NOUN
admet-512	42	9	(	(	PUNCT
admet-512	42	10	2	2	NUM
admet-512	42	11	)	)	PUNCT
admet-512	42	12	n	n	NOUN
admet-512	42	13	=	=	SYM
admet-512	43	1	27	27	NUM
admet-512	43	2	r	r	NOUN
admet-512	43	3	2	2	NUM
admet-512	43	4	=	=	SYM
admet-512	43	5	0.834	0.834	NUM
admet-512	43	6	sd	sd	NOUN
admet-512	43	7	=	=	SYM
admet-512	43	8	0.390	0.390	NUM
admet-512	43	9	f	f	X
admet-512	43	10	=	=	SYM
admet-512	43	11	126	126	NUM
admet-512	43	12	this	this	DET
admet-512	43	13	system	system	NOUN
admet-512	43	14	was	be	AUX
admet-512	43	15	chosen	choose	VERB
admet-512	43	16	to	to	PART
admet-512	43	17	establish	establish	VERB
admet-512	43	18	a	a	DET
admet-512	43	19	methodology	methodology	NOUN
admet-512	43	20	for	for	ADP
admet-512	43	21	the	the	DET
admet-512	43	22	prediction	prediction	NOUN
admet-512	43	23	of	of	ADP
admet-512	43	24	human	human	ADJ
admet-512	43	25	skin	skin	NOUN
admet-512	43	26	permeability	permeability	NOUN
admet-512	43	27	of	of	ADP
admet-512	43	28	untested	untested	ADJ
admet-512	43	29	compounds	compound	NOUN
admet-512	43	30	by	by	ADP
admet-512	43	31	chromatographic	chromatographic	ADJ
admet-512	43	32	measurements	measurement	NOUN
admet-512	43	33	.	.	PUNCT
admet-512	44	1	this	this	DET
admet-512	44	2	methodology	methodology	NOUN
admet-512	44	3	was	be	AUX
admet-512	44	4	developed	develop	VERB
admet-512	44	5	only	only	ADV
admet-512	44	6	for	for	ADP
admet-512	44	7	neutral	neutral	ADJ
admet-512	44	8	compounds	compound	NOUN
admet-512	44	9	at	at	ADP
admet-512	44	10	ph	ph	PROPN
admet-512	44	11	7.0	7.0	NUM
admet-512	44	12	.	.	PUNCT
admet-512	45	1	this	this	DET
admet-512	45	2	study	study	NOUN
admet-512	45	3	has	have	AUX
admet-512	45	4	been	be	AUX
admet-512	45	5	expanded	expand	VERB
admet-512	45	6	in	in	ADP
admet-512	45	7	the	the	DET
admet-512	45	8	present	present	ADJ
admet-512	45	9	work	work	NOUN
admet-512	45	10	to	to	ADP
admet-512	45	11	compounds	compound	NOUN
admet-512	45	12	of	of	ADP
admet-512	45	13	pharmaceutical	pharmaceutical	ADJ
admet-512	45	14	interest	interest	NOUN
admet-512	45	15	with	with	ADP
admet-512	45	16	a	a	DET
admet-512	45	17	wide	wide	ADJ
admet-512	45	18	range	range	NOUN
admet-512	45	19	of	of	ADP
admet-512	45	20	pka	pka	PROPN
admet-512	45	21	values	value	NOUN
admet-512	45	22	,	,	PUNCT
admet-512	45	23	containing	contain	VERB
admet-512	45	24	basic	basic	ADJ
admet-512	45	25	and	and	CCONJ
admet-512	45	26	acidic	acidic	ADJ
admet-512	45	27	functions	function	NOUN
admet-512	45	28	.	.	PUNCT
admet-512	46	1	additionally	additionally	ADV
admet-512	46	2	,	,	PUNCT
admet-512	46	3	a	a	DET
admet-512	46	4	new	new	ADJ
admet-512	46	5	methodology	methodology	NOUN
admet-512	46	6	based	base	VERB
admet-512	46	7	on	on	ADP
admet-512	46	8	fast	fast	ADJ
admet-512	46	9	measurements	measurement	NOUN
admet-512	46	10	by	by	ADP
admet-512	46	11	ms	ms	PROPN
admet-512	46	12	(	(	PUNCT
admet-512	46	13	mass	mass	NOUN
admet-512	46	14	spectrometry	spectrometry	NOUN
admet-512	46	15	)	)	PUNCT
admet-512	46	16	has	have	AUX
admet-512	46	17	been	be	AUX
admet-512	46	18	developed	develop	VERB
admet-512	46	19	and	and	CCONJ
admet-512	46	20	established	establish	VERB
admet-512	46	21	to	to	PART
admet-512	46	22	predict	predict	VERB
admet-512	46	23	kp	kp	PROPN
admet-512	46	24	values	value	NOUN
admet-512	46	25	of	of	ADP
admet-512	46	26	drugs	drug	NOUN
admet-512	46	27	of	of	ADP
admet-512	46	28	pharmaceutical	pharmaceutical	ADJ
admet-512	46	29	interest	interest	NOUN
admet-512	46	30	.	.	PUNCT
admet-512	47	1	materials	material	NOUN
admet-512	47	2	and	and	CCONJ
admet-512	47	3	methods	method	NOUN
admet-512	47	4	instruments	instrument	NOUN
admet-512	47	5	chromatographic	chromatographic	ADJ
admet-512	47	6	measurements	measurement	NOUN
admet-512	47	7	were	be	AUX
admet-512	47	8	performed	perform	VERB
admet-512	47	9	with	with	ADP
admet-512	47	10	an	an	DET
admet-512	47	11	agilent	agilent	PROPN
admet-512	47	12	technologies	technology	NOUN
admet-512	47	13	1200	1200	NUM
admet-512	47	14	series	series	NOUN
admet-512	47	15	instrument	instrument	PROPN
admet-512	47	16	equipped	equip	VERB
admet-512	47	17	with	with	ADP
admet-512	47	18	a	a	DET
admet-512	47	19	g1312b	g1312b	X
admet-512	47	20	binary	binary	NOUN
admet-512	47	21	pump	pump	NOUN
admet-512	47	22	and	and	CCONJ
admet-512	47	23	a	a	DET
admet-512	47	24	g1367d	g1367d	NOUN
admet-512	47	25	autoinjector	autoinjector	NOUN
admet-512	47	26	.	.	PUNCT
admet-512	48	1	a	a	DET
admet-512	48	2	g1315c	g1315c	PROPN
admet-512	48	3	dad	dad	NOUN
admet-512	48	4	was	be	AUX
admet-512	48	5	used	use	VERB
admet-512	48	6	at	at	ADP
admet-512	48	7	254	254	NUM
admet-512	48	8	nm	nm	NOUN
admet-512	48	9	for	for	ADP
admet-512	48	10	non	non	ADJ
admet-512	48	11	-	-	ADJ
admet-512	48	12	ionizable	ionizable	ADJ
admet-512	48	13	compounds	compound	NOUN
admet-512	48	14	and	and	CCONJ
admet-512	48	15	a	a	DET
admet-512	48	16	uhd	uhd	NOUN
admet-512	48	17	6540	6540	NUM
admet-512	48	18	accurate	accurate	ADJ
admet-512	48	19	-	-	PUNCT
admet-512	48	20	mass	mass	NOUN
admet-512	49	1	q	q	NOUN
admet-512	49	2	-	-	PUNCT
admet-512	49	3	tof	tof	PRON
admet-512	49	4	detector	detector	NOUN
admet-512	49	5	with	with	ADP
admet-512	49	6	electrospray	electrospray	ADJ
admet-512	49	7	ionization	ionization	NOUN
admet-512	49	8	(	(	PUNCT
admet-512	49	9	esi	esi	NOUN
admet-512	49	10	)	)	PUNCT
admet-512	49	11	source	source	NOUN
admet-512	49	12	was	be	AUX
admet-512	49	13	used	use	VERB
admet-512	49	14	for	for	ADP
admet-512	49	15	ionizable	ionizable	ADJ
admet-512	49	16	compounds	compound	NOUN
admet-512	49	17	.	.	PUNCT
admet-512	50	1	a	a	DET
admet-512	50	2	100	100	NUM
admet-512	50	3	mm	mm	NOUN
admet-512	50	4	,	,	PUNCT
admet-512	50	5	4.6	4.6	NUM
admet-512	50	6	mm	mm	NOUN
admet-512	50	7	i.d	i.d	PROPN
admet-512	50	8	,	,	PUNCT
admet-512	50	9	2.6	2.6	NUM
admet-512	50	10	µm	µm	ADP
admet-512	50	11	octadecylsilica	octadecylsilica	PROPN
admet-512	50	12	kinetex	kinetex	PROPN
admet-512	50	13	evo	evo	PROPN
admet-512	50	14	c18	c18	PROPN
admet-512	50	15	analytical	analytical	ADJ
admet-512	50	16	column	column	NOUN
admet-512	50	17	provided	provide	VERB
admet-512	50	18	by	by	ADP
admet-512	50	19	phenomenex	phenomenex	ADV
admet-512	50	20	with	with	ADP
admet-512	50	21	a	a	DET
admet-512	50	22	core	core	ADJ
admet-512	50	23	-	-	PUNCT
admet-512	50	24	shell	shell	NOUN
admet-512	50	25	technology	technology	NOUN
admet-512	50	26	was	be	AUX
admet-512	50	27	used	use	VERB
admet-512	50	28	for	for	ADP
admet-512	50	29	all	all	DET
admet-512	50	30	determinations	determination	NOUN
admet-512	50	31	.	.	PUNCT
admet-512	51	1	this	this	DET
admet-512	51	2	material	material	NOUN
admet-512	51	3	is	be	AUX
admet-512	51	4	stable	stable	ADJ
admet-512	51	5	within	within	ADP
admet-512	51	6	the	the	DET
admet-512	51	7	ph	ph	ADJ
admet-512	51	8	range	range	NOUN
admet-512	51	9	1	1	NUM
admet-512	51	10	-	-	SYM
admet-512	51	11	12	12	NUM
admet-512	51	12	.	.	PUNCT
admet-512	52	1	ph	ph	ADJ
admet-512	52	2	measurements	measurement	NOUN
admet-512	52	3	were	be	AUX
admet-512	52	4	done	do	VERB
admet-512	52	5	with	with	ADP
admet-512	52	6	a	a	DET
admet-512	52	7	microph	microph	NOUN
admet-512	52	8	2001	2001	NUM
admet-512	52	9	ph	ph	VERB
admet-512	52	10	-	-	PUNCT
admet-512	52	11	meter	meter	NOUN
admet-512	52	12	(	(	PUNCT
admet-512	52	13	crison	crison	PROPN
admet-512	52	14	)	)	PUNCT
admet-512	52	15	with	with	ADP
admet-512	52	16	a	a	DET
admet-512	52	17	precision	precision	NOUN
admet-512	52	18	of	of	ADP
admet-512	52	19	±	±	NUM
admet-512	52	20	0.01	0.01	NUM
admet-512	52	21	ph	ph	ADJ
admet-512	52	22	units	unit	NOUN
admet-512	52	23	.	.	PUNCT
admet-512	53	1	reagents	reagent	NOUN
admet-512	53	2	acetonitrile	acetonitrile	ADJ
admet-512	53	3	lcms	lcms	PROPN
admet-512	53	4	grade	grade	NOUN
admet-512	53	5	was	be	AUX
admet-512	53	6	purchased	purchase	VERB
admet-512	53	7	from	from	ADP
admet-512	53	8	fluka	fluka	PROPN
admet-512	53	9	analytical	analytical	ADJ
admet-512	53	10	vwr	vwr	PROPN
admet-512	53	11	(	(	PUNCT
admet-512	53	12	west	west	PROPN
admet-512	53	13	chester	chester	PROPN
admet-512	53	14	,	,	PUNCT
admet-512	53	15	pa	pa	PROPN
admet-512	53	16	,	,	PUNCT
admet-512	53	17	usa	usa	PROPN
admet-512	53	18	)	)	PUNCT
admet-512	53	19	and	and	CCONJ
admet-512	53	20	water	water	NOUN
admet-512	53	21	was	be	AUX
admet-512	53	22	purified	purify	VERB
admet-512	53	23	by	by	ADP
admet-512	53	24	a	a	DET
admet-512	53	25	milli	milli	ADJ
admet-512	53	26	-	-	ADJ
admet-512	53	27	q	q	ADJ
admet-512	53	28	deionizing	deionize	VERB
admet-512	53	29	system	system	NOUN
admet-512	53	30	from	from	ADP
admet-512	53	31	millipore	millipore	PROPN
admet-512	53	32	(	(	PUNCT
admet-512	53	33	billerica	billerica	PROPN
admet-512	53	34	,	,	PUNCT
admet-512	53	35	ma	ma	PROPN
admet-512	53	36	,	,	PUNCT
admet-512	53	37	usa	usa	PROPN
admet-512	53	38	)	)	PUNCT
admet-512	53	39	to	to	ADP
admet-512	53	40	a	a	DET
admet-512	53	41	resistivity	resistivity	NOUN
admet-512	53	42	of	of	ADP
admet-512	53	43	18.2	18.2	NUM
admet-512	53	44	m.	m.	NOUN
admet-512	53	45	reagents	reagent	NOUN
admet-512	53	46	used	use	VERB
admet-512	53	47	to	to	PART
admet-512	53	48	prepare	prepare	VERB
admet-512	53	49	the	the	DET
admet-512	53	50	buffer	buffer	NOUN
admet-512	53	51	solutions	solution	NOUN
admet-512	53	52	were	be	AUX
admet-512	53	53	sodium	sodium	NOUN
admet-512	53	54	phosphate	phosphate	ADJ
admet-512	53	55	monobasic	monobasic	NOUN
admet-512	53	56	monohydrate	monohydrate	NOUN
admet-512	53	57	(	(	PUNCT
admet-512	53	58	sigmaaldrich	sigmaaldrich	ADV
admet-512	53	59	,	,	PUNCT
admet-512	53	60	puriss	puriss	ADJ
admet-512	53	61	pa	pa	PROPN
admet-512	53	62	≥99.0	≥99.0	SYM
admet-512	53	63	%	%	NOUN
admet-512	53	64	)	)	PUNCT
admet-512	53	65	,	,	PUNCT
admet-512	53	66	formic	formic	NOUN
admet-512	53	67	acid	acid	NOUN
admet-512	53	68	(	(	PUNCT
admet-512	53	69	scharlau	scharlau	NOUN
admet-512	53	70	,	,	PUNCT
admet-512	53	71	eluent	eluent	NOUN
admet-512	53	72	additive	additive	NOUN
admet-512	53	73	for	for	ADP
admet-512	53	74	lc	lc	PROPN
admet-512	53	75	-	-	PUNCT
admet-512	53	76	ms	ms	NOUN
admet-512	53	77	)	)	PUNCT
admet-512	53	78	,	,	PUNCT
admet-512	53	79	acetic	acetic	ADJ
admet-512	53	80	acid	acid	NOUN
admet-512	53	81	(	(	PUNCT
admet-512	53	82	fluka	fluka	PROPN
admet-512	53	83	analytical	analytical	ADJ
admet-512	53	84	,	,	PUNCT
admet-512	53	85	eluent	eluent	NOUN
admet-512	53	86	additive	additive	NOUN
admet-512	53	87	for	for	ADP
admet-512	53	88	lc	lc	PROPN
admet-512	53	89	-	-	PUNCT
admet-512	53	90	ms	ms	NOUN
admet-512	53	91	)	)	PUNCT
admet-512	53	92	,	,	PUNCT
admet-512	53	93	ethylendiamine	ethylendiamine	INTJ
admet-512	53	94	(	(	PUNCT
admet-512	53	95	fluka	fluka	PROPN
admet-512	53	96	analytical	analytical	NOUN
admet-512	53	97	,	,	PUNCT
admet-512	53	98	puriss	puriss	PROPN
admet-512	53	99	pa	pa	PROPN
admet-512	53	100	≥	≥	NUM
admet-512	53	101	99.5	99.5	NUM
admet-512	53	102	%	%	NOUN
admet-512	53	103	)	)	PUNCT
admet-512	53	104	and	and	CCONJ
admet-512	53	105	ammonia	ammonia	NOUN
admet-512	53	106	solution	solution	NOUN
admet-512	53	107	25	25	NUM
admet-512	53	108	%	%	NOUN
admet-512	53	109	w	w	PROPN
admet-512	53	110	/	/	SYM
admet-512	53	111	w	w	PROPN
admet-512	53	112	(	(	PUNCT
admet-512	53	113	sharlau	sharlau	NOUN
admet-512	53	114	,	,	PUNCT
admet-512	53	115	extrapur	extrapur	NOUN
admet-512	53	116	,	,	PUNCT
admet-512	53	117	pharmpur	pharmpur	NOUN
admet-512	53	118	,	,	PUNCT
admet-512	53	119	ph	ph	ADJ
admet-512	53	120	eur	eur	NOUN
admet-512	53	121	)	)	PUNCT
admet-512	53	122	.	.	PUNCT
admet-512	54	1	most	most	ADJ
admet-512	54	2	drugs	drug	NOUN
admet-512	54	3	were	be	AUX
admet-512	54	4	purchased	purchase	VERB
admet-512	54	5	from	from	ADP
admet-512	54	6	sigma	sigma	PROPN
admet-512	54	7	-	-	PUNCT
admet-512	54	8	aldrich	aldrich	PROPN
admet-512	54	9	(	(	PUNCT
admet-512	54	10	steinheim	steinheim	PROPN
admet-512	54	11	,	,	PUNCT
admet-512	54	12	germany	germany	PROPN
admet-512	54	13	)	)	PUNCT
admet-512	54	14	,	,	PUNCT
admet-512	54	15	fluka	fluka	VERB
admet-512	54	16	analytical	analytical	ADJ
admet-512	54	17	vwr	vwr	PROPN
admet-512	54	18	(	(	PUNCT
admet-512	54	19	west	west	PROPN
admet-512	54	20	chester	chester	PROPN
admet-512	54	21	,	,	PUNCT
admet-512	54	22	pa	pa	PROPN
admet-512	54	23	,	,	PUNCT
admet-512	54	24	usa	usa	PROPN
admet-512	54	25	)	)	PUNCT
admet-512	54	26	,	,	PUNCT
admet-512	54	27	riedel	riedel	NOUN
admet-512	54	28	-	-	PUNCT
admet-512	54	29	de	de	X
admet-512	54	30	haën	haën	PROPN
admet-512	54	31	(	(	PUNCT
admet-512	54	32	seelze	seelze	PROPN
admet-512	54	33	,	,	PUNCT
admet-512	54	34	germany	germany	PROPN
admet-512	54	35	)	)	PUNCT
admet-512	54	36	,	,	PUNCT
admet-512	54	37	merck	merck	PROPN
admet-512	54	38	(	(	PUNCT
admet-512	54	39	darmstadt	darmstadt	PROPN
admet-512	54	40	,	,	PUNCT
admet-512	54	41	germany	germany	PROPN
admet-512	54	42	)	)	PUNCT
admet-512	54	43	,	,	PUNCT
admet-512	54	44	carlo	carlo	PROPN
admet-512	54	45	erba	erba	PROPN
admet-512	54	46	(	(	PUNCT
admet-512	54	47	milano	milano	PROPN
admet-512	54	48	,	,	PUNCT
admet-512	54	49	italy	italy	PROPN
admet-512	54	50	)	)	PUNCT
admet-512	54	51	and	and	CCONJ
admet-512	54	52	baker	baker	PROPN
admet-512	54	53	(	(	PUNCT
admet-512	54	54	center	center	PROPN
admet-512	54	55	valley	valley	NOUN
admet-512	54	56	,	,	PUNCT
admet-512	54	57	pa	pa	PROPN
admet-512	54	58	,	,	PUNCT
admet-512	54	59	usa	usa	PROPN
admet-512	54	60	)	)	PUNCT
admet-512	54	61	.	.	PUNCT
admet-512	55	1	other	other	ADJ
admet-512	55	2	drugs	drug	NOUN
admet-512	55	3	were	be	AUX
admet-512	55	4	synthesized	synthesize	VERB
admet-512	55	5	in	in	ADP
admet-512	55	6	esteve	esteve	PROPN
admet-512	55	7	(	(	PUNCT
admet-512	55	8	barcelona	barcelona	PROPN
admet-512	55	9	,	,	PUNCT
admet-512	55	10	spain	spain	PROPN
admet-512	55	11	)	)	PUNCT
admet-512	55	12	only	only	ADV
admet-512	55	13	for	for	ADP
admet-512	55	14	the	the	DET
admet-512	55	15	purpose	purpose	NOUN
admet-512	55	16	of	of	ADP
admet-512	55	17	this	this	DET
admet-512	55	18	study	study	NOUN
admet-512	55	19	.	.	PUNCT
admet-512	56	1	admet	admet	PROPN
admet-512	56	2	&	&	CCONJ
admet-512	56	3	dmpk	dmpk	PROPN
admet-512	56	4	6(2	6(2	NUM
admet-512	56	5	)	)	PUNCT
admet-512	56	6	(	(	PUNCT
admet-512	56	7	2018	2018	NUM
admet-512	56	8	)	)	PUNCT
admet-512	56	9	140	140	NUM
admet-512	56	10	-	-	SYM
admet-512	56	11	152	152	NUM
admet-512	56	12	estimation	estimation	NOUN
admet-512	56	13	of	of	ADP
admet-512	56	14	skin	skin	NOUN
admet-512	56	15	permeation	permeation	NOUN
admet-512	56	16	by	by	ADP
admet-512	56	17	liquid	liquid	ADJ
admet-512	56	18	chromatography	chromatography	NOUN
admet-512	56	19	doi	doi	NOUN
admet-512	56	20	:	:	PUNCT
admet-512	56	21	10.5599	10.5599	NUM
admet-512	56	22	/	/	SYM
admet-512	56	23	admet.512	admet.512	NOUN
admet-512	56	24	143	143	PRON
admet-512	56	25	procedure	procedure	NOUN
admet-512	56	26	94	94	NUM
admet-512	56	27	solutes	solute	NOUN
admet-512	56	28	of	of	ADP
admet-512	56	29	different	different	ADJ
admet-512	56	30	chemical	chemical	NOUN
admet-512	56	31	nature	nature	NOUN
admet-512	56	32	were	be	AUX
admet-512	56	33	injected	inject	VERB
admet-512	56	34	in	in	ADP
admet-512	56	35	the	the	DET
admet-512	56	36	hplc	hplc	NOUN
admet-512	56	37	system	system	NOUN
admet-512	56	38	at	at	ADP
admet-512	56	39	6	6	NUM
admet-512	56	40	different	different	ADJ
admet-512	56	41	ph	ph	ADJ
admet-512	56	42	values	value	NOUN
admet-512	56	43	,	,	PUNCT
admet-512	56	44	between	between	ADP
admet-512	56	45	2	2	NUM
admet-512	56	46	and	and	CCONJ
admet-512	56	47	11	11	NUM
admet-512	56	48	,	,	PUNCT
admet-512	56	49	to	to	PART
admet-512	56	50	obtain	obtain	VERB
admet-512	56	51	the	the	DET
admet-512	56	52	retention	retention	NOUN
admet-512	56	53	factors	factor	NOUN
admet-512	56	54	of	of	ADP
admet-512	56	55	the	the	DET
admet-512	56	56	neutral	neutral	ADJ
admet-512	56	57	species	specie	NOUN
admet-512	56	58	.	.	PUNCT
admet-512	57	1	the	the	DET
admet-512	57	2	mobile	mobile	ADJ
admet-512	57	3	phase	phase	NOUN
admet-512	57	4	composition	composition	NOUN
admet-512	57	5	was	be	AUX
admet-512	57	6	40	40	NUM
admet-512	57	7	%	%	NOUN
admet-512	57	8	acetonitrile	acetonitrile	NOUN
admet-512	57	9	and	and	CCONJ
admet-512	57	10	60	60	NUM
admet-512	57	11	%	%	NOUN
admet-512	57	12	aqueous	aqueous	ADJ
admet-512	57	13	buffer	buffer	NOUN
admet-512	57	14	.	.	PUNCT
admet-512	58	1	the	the	DET
admet-512	58	2	buffer	buffer	NOUN
admet-512	58	3	solutions	solution	NOUN
admet-512	58	4	were	be	AUX
admet-512	58	5	selected	select	VERB
admet-512	58	6	according	accord	VERB
admet-512	58	7	to	to	ADP
admet-512	58	8	their	their	PRON
admet-512	58	9	compatibility	compatibility	NOUN
admet-512	58	10	with	with	ADP
admet-512	58	11	the	the	DET
admet-512	58	12	detection	detection	NOUN
admet-512	58	13	mode	mode	NOUN
admet-512	58	14	.	.	PUNCT
admet-512	59	1	volatile	volatile	ADJ
admet-512	59	2	buffers	buffer	NOUN
admet-512	59	3	were	be	AUX
admet-512	59	4	used	use	VERB
admet-512	59	5	for	for	ADP
admet-512	59	6	mass	mass	ADJ
admet-512	59	7	spectrometry	spectrometry	NOUN
admet-512	59	8	detection	detection	NOUN
admet-512	59	9	.	.	PUNCT
admet-512	60	1	formic	formic	ADJ
admet-512	60	2	acid	acid	PROPN
admet-512	60	3	,	,	PUNCT
admet-512	60	4	acetic	acetic	ADJ
admet-512	60	5	acid	acid	NOUN
admet-512	60	6	and	and	CCONJ
admet-512	60	7	ammonia	ammonia	NOUN
admet-512	60	8	solution	solution	NOUN
admet-512	60	9	were	be	AUX
admet-512	60	10	used	use	VERB
admet-512	60	11	at	at	ADP
admet-512	60	12	ph	ph	PROPN
admet-512	60	13	3.0	3.0	NUM
admet-512	60	14	,	,	PUNCT
admet-512	60	15	5.0	5.0	NUM
admet-512	60	16	and	and	CCONJ
admet-512	60	17	9.0	9.0	NUM
admet-512	60	18	,	,	PUNCT
admet-512	60	19	respectively	respectively	ADV
admet-512	60	20	.	.	PUNCT
admet-512	61	1	ethylendiamine	ethylendiamine	PROPN
admet-512	61	2	was	be	AUX
admet-512	61	3	used	use	VERB
admet-512	61	4	at	at	ADP
admet-512	61	5	ph	ph	PROPN
admet-512	61	6	7.0	7.0	NUM
admet-512	61	7	and	and	CCONJ
admet-512	61	8	11.0	11.0	NUM
admet-512	61	9	.	.	PUNCT
admet-512	62	1	the	the	DET
admet-512	62	2	buffer	buffer	NOUN
admet-512	62	3	concentrations	concentration	NOUN
admet-512	62	4	at	at	ADP
admet-512	62	5	ph	ph	ADJ
admet-512	62	6	3.0	3.0	NUM
admet-512	62	7	,	,	PUNCT
admet-512	62	8	5.0	5.0	NUM
admet-512	62	9	,	,	PUNCT
admet-512	62	10	7.0	7.0	NUM
admet-512	62	11	,	,	PUNCT
admet-512	62	12	9.0	9.0	NUM
admet-512	62	13	and	and	CCONJ
admet-512	62	14	11.0	11.0	NUM
admet-512	62	15	were	be	AUX
admet-512	62	16	10	10	NUM
admet-512	62	17	mm	mm	NUM
admet-512	62	18	and	and	CCONJ
admet-512	62	19	were	be	AUX
admet-512	62	20	adjusted	adjust	VERB
admet-512	62	21	by	by	ADP
admet-512	62	22	addition	addition	NOUN
admet-512	62	23	of	of	ADP
admet-512	62	24	diluted	diluted	ADJ
admet-512	62	25	acetic	acetic	ADJ
admet-512	62	26	acid	acid	NOUN
admet-512	62	27	or	or	CCONJ
admet-512	62	28	diluted	diluted	ADJ
admet-512	62	29	ammonia	ammonia	NOUN
admet-512	62	30	.	.	PUNCT
admet-512	63	1	the	the	DET
admet-512	63	2	detection	detection	NOUN
admet-512	63	3	mode	mode	NOUN
admet-512	63	4	was	be	AUX
admet-512	63	5	esi+	esi+	NOUN
admet-512	63	6	or	or	CCONJ
admet-512	63	7	esifor	esifor	ADJ
admet-512	63	8	ionizable	ionizable	ADJ
admet-512	63	9	compounds	compound	NOUN
admet-512	63	10	and	and	CCONJ
admet-512	63	11	uv	uv	NOUN
admet-512	63	12	for	for	ADP
admet-512	63	13	non	non	ADJ
admet-512	63	14	-	-	ADJ
admet-512	63	15	ionizable	ionizable	ADJ
admet-512	63	16	compounds	compound	NOUN
admet-512	63	17	.	.	PUNCT
admet-512	64	1	for	for	ADP
admet-512	64	2	mass	mass	ADJ
admet-512	64	3	spectrometry	spectrometry	NOUN
admet-512	64	4	detection	detection	NOUN
admet-512	64	5	,	,	PUNCT
admet-512	64	6	the	the	DET
admet-512	64	7	compounds	compound	NOUN
admet-512	64	8	were	be	AUX
admet-512	64	9	grouped	group	VERB
admet-512	64	10	for	for	ADP
admet-512	64	11	faster	fast	ADJ
admet-512	64	12	analysis	analysis	NOUN
admet-512	64	13	.	.	PUNCT
admet-512	65	1	at	at	ADP
admet-512	65	2	ph	ph	PROPN
admet-512	65	3	2.0	2.0	NUM
admet-512	65	4	,	,	PUNCT
admet-512	65	5	the	the	DET
admet-512	65	6	detection	detection	NOUN
admet-512	65	7	was	be	AUX
admet-512	65	8	only	only	ADV
admet-512	65	9	performed	perform	VERB
admet-512	65	10	by	by	ADP
admet-512	65	11	uv	uv	NOUN
admet-512	65	12	and	and	CCONJ
admet-512	65	13	a	a	DET
admet-512	65	14	mixture	mixture	NOUN
admet-512	65	15	of	of	ADP
admet-512	65	16	phosphoric	phosphoric	ADJ
admet-512	65	17	acid	acid	NOUN
admet-512	65	18	and	and	CCONJ
admet-512	65	19	sodium	sodium	NOUN
admet-512	65	20	dihydrogenphosphate	dihydrogenphosphate	NOUN
admet-512	65	21	was	be	AUX
admet-512	65	22	used	use	VERB
admet-512	65	23	as	as	ADP
admet-512	65	24	buffer	buffer	NOUN
admet-512	65	25	,	,	PUNCT
admet-512	65	26	at	at	ADP
admet-512	65	27	a	a	DET
admet-512	65	28	concentration	concentration	NOUN
admet-512	65	29	of	of	ADP
admet-512	65	30	50	50	NUM
admet-512	65	31	mm	mm	NOUN
admet-512	65	32	.	.	PUNCT
admet-512	66	1	ph	ph	PROPN
admet-512	66	2	was	be	AUX
admet-512	66	3	adjusted	adjust	VERB
admet-512	66	4	with	with	ADP
admet-512	66	5	diluted	diluted	ADJ
admet-512	66	6	hydrochloric	hydrochloric	ADJ
admet-512	66	7	acid	acid	NOUN
admet-512	66	8	.	.	PUNCT
admet-512	67	1	all	all	DET
admet-512	67	2	experiments	experiment	NOUN
admet-512	67	3	were	be	AUX
admet-512	67	4	done	do	VERB
admet-512	67	5	at	at	ADP
admet-512	67	6	25	25	NUM
admet-512	67	7	°	°	NOUN
admet-512	67	8	c	c	NOUN
admet-512	67	9	.	.	PUNCT
admet-512	68	1	stock	stock	NOUN
admet-512	68	2	solutions	solution	NOUN
admet-512	68	3	of	of	ADP
admet-512	68	4	the	the	DET
admet-512	68	5	compounds	compound	NOUN
admet-512	68	6	at	at	ADP
admet-512	68	7	5000	5000	NUM
admet-512	68	8	mg·l	mg·l	NOUN
admet-512	68	9	-1	-1	ADP
admet-512	68	10	were	be	AUX
admet-512	68	11	prepared	prepare	VERB
admet-512	68	12	by	by	ADP
admet-512	68	13	dissolving	dissolve	VERB
admet-512	68	14	the	the	DET
admet-512	68	15	appropriate	appropriate	ADJ
admet-512	68	16	weight	weight	NOUN
admet-512	68	17	or	or	CCONJ
admet-512	68	18	volume	volume	NOUN
admet-512	68	19	in	in	ADP
admet-512	68	20	methanol	methanol	NOUN
admet-512	68	21	.	.	PUNCT
admet-512	69	1	more	more	ADV
admet-512	69	2	diluted	diluted	ADJ
admet-512	69	3	solutions	solution	NOUN
admet-512	69	4	were	be	AUX
admet-512	69	5	prepared	prepare	VERB
admet-512	69	6	at	at	ADP
admet-512	69	7	100	100	NUM
admet-512	69	8	mg·l	mg·l	NOUN
admet-512	69	9	-1	-1	PUNCT
admet-512	69	10	by	by	ADP
admet-512	69	11	dissolving	dissolve	VERB
admet-512	69	12	an	an	DET
admet-512	69	13	aliquot	aliquot	NOUN
admet-512	69	14	of	of	ADP
admet-512	69	15	the	the	DET
admet-512	69	16	previous	previous	ADJ
admet-512	69	17	stock	stock	NOUN
admet-512	69	18	solution	solution	NOUN
admet-512	69	19	in	in	ADP
admet-512	69	20	an	an	DET
admet-512	69	21	acn	acn	PROPN
admet-512	69	22	-	-	PUNCT
admet-512	69	23	h2o	h2o	PROPN
admet-512	69	24	mixture	mixture	NOUN
admet-512	69	25	(	(	PUNCT
admet-512	69	26	40:60	40:60	NUM
admet-512	69	27	)	)	PUNCT
admet-512	69	28	.	.	PUNCT
admet-512	70	1	isocratic	isocratic	ADJ
admet-512	70	2	conditions	condition	NOUN
admet-512	70	3	were	be	AUX
admet-512	70	4	used	use	VERB
admet-512	70	5	at	at	ADP
admet-512	70	6	a	a	DET
admet-512	70	7	flow	flow	NOUN
admet-512	70	8	rate	rate	NOUN
admet-512	70	9	of	of	ADP
admet-512	70	10	1	1	NUM
admet-512	70	11	ml	ml	NOUN
admet-512	70	12	min	min	NOUN
admet-512	70	13	-1	-1	PROPN
admet-512	70	14	and	and	CCONJ
admet-512	70	15	the	the	DET
admet-512	70	16	injection	injection	NOUN
admet-512	70	17	volume	volume	NOUN
admet-512	70	18	was	be	AUX
admet-512	70	19	10	10	NUM
admet-512	70	20	µl	µl	NOUN
admet-512	70	21	.	.	PUNCT
admet-512	71	1	the	the	DET
admet-512	71	2	column	column	NOUN
admet-512	71	3	hold	hold	VERB
admet-512	71	4	-	-	PUNCT
admet-512	71	5	up	up	ADP
admet-512	71	6	time	time	NOUN
admet-512	71	7	was	be	AUX
admet-512	71	8	measured	measure	VERB
admet-512	71	9	by	by	ADP
admet-512	71	10	injections	injection	NOUN
admet-512	71	11	of	of	ADP
admet-512	71	12	an	an	DET
admet-512	71	13	aqueous	aqueous	ADJ
admet-512	71	14	solution	solution	NOUN
admet-512	71	15	of	of	ADP
admet-512	71	16	potassium	potassium	NOUN
admet-512	71	17	bromide	bromide	NOUN
admet-512	71	18	(	(	PUNCT
admet-512	71	19	0.1	0.1	NUM
admet-512	71	20	mg	mg	PROPN
admet-512	71	21	ml-1	ml-1	NUM
admet-512	71	22	)	)	PUNCT
admet-512	71	23	,	,	PUNCT
admet-512	71	24	whose	whose	DET
admet-512	71	25	detection	detection	NOUN
admet-512	71	26	was	be	AUX
admet-512	71	27	performed	perform	VERB
admet-512	71	28	by	by	ADP
admet-512	71	29	uv	uv	NOUN
admet-512	71	30	at	at	ADP
admet-512	71	31	200	200	NUM
admet-512	71	32	nm	nm	NOUN
admet-512	71	33	.	.	PUNCT
admet-512	72	1	all	all	DET
admet-512	72	2	results	result	NOUN
admet-512	72	3	were	be	AUX
admet-512	72	4	the	the	DET
admet-512	72	5	average	average	NOUN
admet-512	72	6	of	of	ADP
admet-512	72	7	triplicate	triplicate	NOUN
admet-512	72	8	injections	injection	NOUN
admet-512	72	9	.	.	PUNCT
admet-512	73	1	the	the	DET
admet-512	73	2	hplc	hplc	NOUN
admet-512	73	3	retention	retention	NOUN
admet-512	73	4	factor	factor	NOUN
admet-512	73	5	(	(	PUNCT
admet-512	73	6	k	k	NOUN
admet-512	73	7	)	)	PUNCT
admet-512	73	8	was	be	AUX
admet-512	73	9	calculated	calculate	VERB
admet-512	73	10	according	accord	VERB
admet-512	73	11	to	to	ADP
admet-512	73	12	eq	eq	PROPN
admet-512	73	13	.	.	PROPN
admet-512	73	14	3	3	NUM
admet-512	73	15	,	,	PUNCT
admet-512	73	16	r	r	NOUN
admet-512	73	17	0	0	NUM
admet-512	73	18	0	0	NUM
admet-512	73	19	e	e	NOUN
admet-512	73	20	t	t	PROPN
admet-512	73	21	t	t	PROPN
admet-512	73	22	k	k	PROPN
admet-512	73	23	t	t	PROPN
admet-512	73	24	t	t	PROPN
admet-512	73	25			PROPN
admet-512	73	26			PROPN
admet-512	73	27			NOUN
admet-512	73	28	(	(	PUNCT
admet-512	73	29	3	3	NUM
admet-512	73	30	)	)	PUNCT
admet-512	73	31	where	where	SCONJ
admet-512	73	32	tr	tr	NOUN
admet-512	73	33	corresponds	correspond	VERB
admet-512	73	34	to	to	ADP
admet-512	73	35	the	the	DET
admet-512	73	36	solute	solute	NOUN
admet-512	73	37	retention	retention	NOUN
admet-512	73	38	time	time	NOUN
admet-512	73	39	,	,	PUNCT
admet-512	73	40	t0	t0	PROPN
admet-512	73	41	is	be	AUX
admet-512	73	42	the	the	DET
admet-512	73	43	column	column	NOUN
admet-512	73	44	hold	hold	VERB
admet-512	73	45	-	-	PUNCT
admet-512	73	46	up	up	ADP
admet-512	73	47	time	time	NOUN
admet-512	73	48	determined	determine	VERB
admet-512	73	49	by	by	ADP
admet-512	73	50	an	an	DET
admet-512	73	51	aqueous	aqueous	ADJ
admet-512	73	52	potassium	potassium	NOUN
admet-512	73	53	bromide	bromide	NOUN
admet-512	73	54	solution	solution	NOUN
admet-512	73	55	,	,	PUNCT
admet-512	73	56	and	and	CCONJ
admet-512	73	57	te	te	PROPN
admet-512	73	58	is	be	AUX
admet-512	73	59	the	the	DET
admet-512	73	60	extra	extra	ADJ
admet-512	73	61	column	column	NOUN
admet-512	73	62	time	time	NOUN
admet-512	73	63	determined	determine	VERB
admet-512	73	64	by	by	ADP
admet-512	73	65	an	an	DET
admet-512	73	66	analysis	analysis	NOUN
admet-512	73	67	that	that	PRON
admet-512	73	68	excludes	exclude	VERB
admet-512	73	69	the	the	DET
admet-512	73	70	chromatographic	chromatographic	ADJ
admet-512	73	71	column	column	NOUN
admet-512	73	72	,	,	PUNCT
admet-512	73	73	for	for	ADP
admet-512	73	74	each	each	DET
admet-512	73	75	different	different	ADJ
admet-512	73	76	detection	detection	NOUN
admet-512	73	77	system	system	NOUN
admet-512	73	78	.	.	PUNCT
admet-512	74	1	calculation	calculation	NOUN
admet-512	74	2	microsoft	microsoft	PROPN
admet-512	74	3	excel	excel	VERB
admet-512	74	4	2010	2010	NUM
admet-512	74	5	was	be	AUX
admet-512	74	6	used	use	VERB
admet-512	74	7	for	for	ADP
admet-512	74	8	all	all	DET
admet-512	74	9	calculations	calculation	NOUN
admet-512	74	10	and	and	CCONJ
admet-512	74	11	for	for	ADP
admet-512	74	12	multiple	multiple	ADJ
admet-512	74	13	linear	linear	ADJ
admet-512	74	14	regression	regression	NOUN
admet-512	74	15	analysis	analysis	NOUN
admet-512	74	16	.	.	PUNCT
admet-512	75	1	solvation	solvation	NOUN
admet-512	75	2	parameter	parameter	NOUN
admet-512	75	3	model	model	NOUN
admet-512	75	4	descriptors	descriptor	NOUN
admet-512	75	5	of	of	ADP
admet-512	75	6	the	the	DET
admet-512	75	7	compounds	compound	NOUN
admet-512	75	8	(	(	PUNCT
admet-512	75	9	e	e	NOUN
admet-512	75	10	,	,	PUNCT
admet-512	75	11	s	s	PROPN
admet-512	75	12	,	,	PUNCT
admet-512	75	13	a	a	DET
admet-512	75	14	,	,	PUNCT
admet-512	75	15	b	b	NOUN
admet-512	75	16	,	,	PUNCT
admet-512	75	17	v	v	NOUN
admet-512	75	18	)	)	PUNCT
admet-512	75	19	were	be	AUX
admet-512	75	20	obtained	obtain	VERB
admet-512	75	21	from	from	ADP
admet-512	75	22	percepta	percepta	NOUN
admet-512	75	23	[	[	X
admet-512	75	24	21	21	NUM
admet-512	75	25	]	]	PUNCT
admet-512	75	26	.	.	PUNCT
admet-512	76	1	matlab	matlab	PROPN
admet-512	76	2	®	®	PROPN
admet-512	76	3	(	(	PUNCT
admet-512	76	4	mathworks	mathworks	PROPN
admet-512	76	5	)	)	PUNCT
admet-512	76	6	was	be	AUX
admet-512	76	7	used	use	VERB
admet-512	76	8	for	for	ADP
admet-512	76	9	principal	principal	ADJ
admet-512	76	10	components	component	NOUN
admet-512	76	11	analysis	analysis	NOUN
admet-512	76	12	(	(	PUNCT
admet-512	76	13	pca	pca	NOUN
admet-512	76	14	)	)	PUNCT
admet-512	76	15	.	.	PUNCT
admet-512	77	1	model	model	NOUN
admet-512	77	2	establishment	establishment	NOUN
admet-512	77	3	and	and	CCONJ
admet-512	77	4	validation	validation	NOUN
admet-512	77	5	data	datum	NOUN
admet-512	77	6	collection	collection	NOUN
admet-512	77	7	the	the	DET
admet-512	77	8	evaluation	evaluation	NOUN
admet-512	77	9	of	of	ADP
admet-512	77	10	the	the	DET
admet-512	77	11	consistency	consistency	NOUN
admet-512	77	12	and	and	CCONJ
admet-512	77	13	quality	quality	NOUN
admet-512	77	14	of	of	ADP
admet-512	77	15	the	the	DET
admet-512	77	16	experimental	experimental	ADJ
admet-512	77	17	skin	skin	NOUN
admet-512	77	18	permeation	permeation	NOUN
admet-512	77	19	data	datum	NOUN
admet-512	77	20	used	use	VERB
admet-512	77	21	is	be	AUX
admet-512	77	22	fundamental	fundamental	ADJ
admet-512	77	23	to	to	ADP
admet-512	77	24	the	the	DET
admet-512	77	25	establishment	establishment	NOUN
admet-512	77	26	of	of	ADP
admet-512	77	27	a	a	DET
admet-512	77	28	good	good	ADJ
admet-512	77	29	prediction	prediction	NOUN
admet-512	77	30	model	model	NOUN
admet-512	77	31	.	.	PUNCT
admet-512	78	1	for	for	ADP
admet-512	78	2	any	any	DET
admet-512	78	3	qsar	qsar	NOUN
admet-512	78	4	model	model	NOUN
admet-512	78	5	,	,	PUNCT
admet-512	78	6	experimental	experimental	ADJ
admet-512	78	7	data	datum	NOUN
admet-512	78	8	should	should	AUX
admet-512	78	9	be	be	AUX
admet-512	78	10	produced	produce	VERB
admet-512	78	11	from	from	ADP
admet-512	78	12	standardized	standardized	ADJ
admet-512	78	13	experimental	experimental	ADJ
admet-512	78	14	procedures	procedure	NOUN
admet-512	78	15	,	,	PUNCT
admet-512	78	16	and	and	CCONJ
admet-512	78	17	obtained	obtain	VERB
admet-512	78	18	for	for	ADP
admet-512	78	19	a	a	DET
admet-512	78	20	set	set	NOUN
admet-512	78	21	of	of	ADP
admet-512	78	22	chemicals	chemical	NOUN
admet-512	78	23	that	that	PRON
admet-512	78	24	cover	cover	VERB
admet-512	78	25	the	the	DET
admet-512	78	26	domain	domain	NOUN
admet-512	78	27	of	of	ADP
admet-512	78	28	relevant	relevant	ADJ
admet-512	78	29	chemical	chemical	NOUN
admet-512	78	30	properties	property	NOUN
admet-512	78	31	[	[	X
admet-512	78	32	22	22	NUM
admet-512	78	33	]	]	PUNCT
admet-512	78	34	.	.	PUNCT
admet-512	79	1	several	several	ADJ
admet-512	79	2	studies	study	NOUN
admet-512	79	3	that	that	PRON
admet-512	79	4	have	have	AUX
admet-512	79	5	focused	focus	VERB
admet-512	79	6	on	on	ADP
admet-512	79	7	the	the	DET
admet-512	79	8	determination	determination	NOUN
admet-512	79	9	of	of	ADP
admet-512	79	10	skin	skin	NOUN
admet-512	79	11	permeability	permeability	NOUN
admet-512	79	12	coefficients	coefficient	NOUN
admet-512	79	13	[	[	X
admet-512	79	14	23	23	NUM
admet-512	79	15	-	-	SYM
admet-512	79	16	25	25	NUM
admet-512	79	17	]	]	PUNCT
admet-512	79	18	have	have	AUX
admet-512	79	19	pointed	point	VERB
admet-512	79	20	out	out	ADP
admet-512	79	21	that	that	SCONJ
admet-512	79	22	interand	interand	VERB
admet-512	79	23	intra	intra	ADJ
admet-512	79	24	-	-	NOUN
admet-512	79	25	variability	variability	NOUN
admet-512	79	26	within	within	ADP
admet-512	79	27	experimental	experimental	ADJ
admet-512	79	28	kp	kp	PROPN
admet-512	79	29	values	value	NOUN
admet-512	79	30	is	be	AUX
admet-512	79	31	mainly	mainly	ADV
admet-512	79	32	due	due	ADJ
admet-512	79	33	to	to	ADP
admet-512	79	34	the	the	DET
admet-512	79	35	thickness	thickness	NOUN
admet-512	79	36	of	of	ADP
admet-512	79	37	the	the	DET
admet-512	79	38	skin	skin	NOUN
admet-512	79	39	and	and	CCONJ
admet-512	79	40	also	also	ADV
admet-512	79	41	to	to	ADP
admet-512	79	42	the	the	DET
admet-512	79	43	variability	variability	NOUN
admet-512	79	44	inherent	inherent	ADJ
admet-512	79	45	to	to	ADP
admet-512	79	46	different	different	ADJ
admet-512	79	47	human	human	ADJ
admet-512	79	48	donors	donor	NOUN
admet-512	79	49	.	.	PUNCT
admet-512	80	1	in	in	ADP
admet-512	80	2	this	this	DET
admet-512	80	3	work	work	NOUN
admet-512	80	4	,	,	PUNCT
admet-512	80	5	the	the	DET
admet-512	80	6	permeation	permeation	NOUN
admet-512	80	7	data	datum	NOUN
admet-512	80	8	employed	employ	VERB
admet-512	80	9	was	be	AUX
admet-512	80	10	selected	select	VERB
admet-512	80	11	from	from	ADP
admet-512	80	12	the	the	DET
admet-512	80	13	abraham	abraham	PROPN
admet-512	80	14	database	database	NOUN
admet-512	81	1	[	[	X
admet-512	81	2	15	15	NUM
admet-512	81	3	]	]	X
admet-512	81	4	,	,	PUNCT
admet-512	81	5	an	an	DET
admet-512	81	6	extensive	extensive	ADJ
admet-512	81	7	and	and	CCONJ
admet-512	81	8	carefully	carefully	ADV
admet-512	81	9	examined	examine	VERB
admet-512	81	10	data	datum	NOUN
admet-512	81	11	set	set	VERB
admet-512	81	12	.	.	PUNCT
admet-512	82	1	65	65	NUM
admet-512	82	2	solutes	solute	NOUN
admet-512	82	3	that	that	PRON
admet-512	82	4	belong	belong	VERB
admet-512	82	5	to	to	ADP
admet-512	82	6	different	different	ADJ
admet-512	82	7	families	family	NOUN
admet-512	82	8	,	,	PUNCT
admet-512	82	9	with	with	ADP
admet-512	82	10	different	different	ADJ
admet-512	82	11	structural	structural	ADJ
admet-512	82	12	complexity	complexity	NOUN
admet-512	82	13	and	and	CCONJ
admet-512	82	14	with	with	ADP
admet-512	82	15	varied	varied	ADJ
admet-512	82	16	experimental	experimental	ADJ
admet-512	82	17	marti	marti	PROPN
admet-512	82	18	rosés	rosé	NOUN
admet-512	82	19	et	et	PROPN
admet-512	82	20	al	al	PROPN
admet-512	82	21	admet	admet	PROPN
admet-512	82	22	&	&	CCONJ
admet-512	82	23	dmpk	dmpk	PROPN
admet-512	82	24	6(2	6(2	NUM
admet-512	82	25	)	)	PUNCT
admet-512	82	26	(	(	PUNCT
admet-512	82	27	2018	2018	NUM
admet-512	82	28	)	)	PUNCT
admet-512	82	29	140	140	NUM
admet-512	82	30	-	-	SYM
admet-512	82	31	152	152	NUM
admet-512	82	32	144	144	NUM
admet-512	82	33	log	log	NOUN
admet-512	82	34	kp	kp	PROPN
admet-512	82	35	values	value	NOUN
admet-512	82	36	were	be	AUX
admet-512	82	37	selected	select	VERB
admet-512	82	38	to	to	PART
admet-512	82	39	develop	develop	VERB
admet-512	82	40	this	this	DET
admet-512	82	41	model	model	NOUN
admet-512	82	42	.	.	PUNCT
admet-512	83	1	because	because	SCONJ
admet-512	83	2	the	the	DET
admet-512	83	3	permeation	permeation	NOUN
admet-512	83	4	coefficients	coefficient	NOUN
admet-512	83	5	are	be	AUX
admet-512	83	6	from	from	ADP
admet-512	83	7	water	water	NOUN
admet-512	83	8	through	through	ADP
admet-512	83	9	human	human	ADJ
admet-512	83	10	skin	skin	NOUN
admet-512	83	11	,	,	PUNCT
admet-512	83	12	it	it	PRON
admet-512	83	13	might	might	AUX
admet-512	83	14	be	be	AUX
admet-512	83	15	expected	expect	VERB
admet-512	83	16	that	that	SCONJ
admet-512	83	17	acids	acid	NOUN
admet-512	83	18	and	and	CCONJ
admet-512	83	19	bases	basis	NOUN
admet-512	83	20	would	would	AUX
admet-512	83	21	be	be	AUX
admet-512	83	22	partially	partially	ADV
admet-512	83	23	ionized	ionize	VERB
admet-512	83	24	in	in	ADP
admet-512	83	25	solution	solution	NOUN
admet-512	83	26	depending	depend	VERB
admet-512	83	27	on	on	ADP
admet-512	83	28	the	the	DET
admet-512	83	29	ph	ph	NOUN
admet-512	83	30	of	of	ADP
admet-512	83	31	the	the	DET
admet-512	83	32	solution	solution	NOUN
admet-512	83	33	.	.	PUNCT
admet-512	84	1	values	value	NOUN
admet-512	84	2	of	of	ADP
admet-512	84	3	kp	kp	PROPN
admet-512	84	4	for	for	ADP
admet-512	84	5	ionized	ionized	ADJ
admet-512	84	6	species	specie	NOUN
admet-512	84	7	are	be	AUX
admet-512	84	8	smaller	small	ADJ
admet-512	84	9	than	than	ADP
admet-512	84	10	kp	kp	PROPN
admet-512	84	11	values	value	NOUN
admet-512	84	12	for	for	ADP
admet-512	84	13	the	the	DET
admet-512	84	14	neutral	neutral	ADJ
admet-512	84	15	species	specie	NOUN
admet-512	84	16	.	.	PUNCT
admet-512	85	1	in	in	ADP
admet-512	85	2	these	these	DET
admet-512	85	3	cases	case	NOUN
admet-512	85	4	,	,	PUNCT
admet-512	85	5	abraham	abraham	PROPN
admet-512	85	6	adjusted	adjust	VERB
admet-512	85	7	the	the	DET
admet-512	85	8	literature	literature	NOUN
admet-512	85	9	values	value	NOUN
admet-512	85	10	of	of	ADP
admet-512	85	11	the	the	DET
admet-512	85	12	skin	skin	NOUN
admet-512	85	13	-	-	PUNCT
admet-512	85	14	water	water	NOUN
admet-512	85	15	permeability	permeability	NOUN
admet-512	85	16	coefficients	coefficient	NOUN
admet-512	85	17	for	for	ADP
admet-512	85	18	ionization	ionization	NOUN
admet-512	85	19	in	in	ADP
admet-512	85	20	water	water	NOUN
admet-512	85	21	and	and	CCONJ
admet-512	85	22	for	for	ADP
admet-512	85	23	a	a	DET
admet-512	85	24	temperature	temperature	NOUN
admet-512	85	25	of	of	ADP
admet-512	85	26	37	37	NUM
admet-512	85	27	°	°	NOUN
admet-512	85	28	c	c	NOUN
admet-512	85	29	[	[	X
admet-512	85	30	15	15	NUM
admet-512	85	31	]	]	PUNCT
admet-512	85	32	.	.	PUNCT
admet-512	86	1	a	a	DET
admet-512	86	2	different	different	ADJ
admet-512	86	3	set	set	NOUN
admet-512	86	4	of	of	ADP
admet-512	86	5	29	29	NUM
admet-512	86	6	solutes	solute	NOUN
admet-512	86	7	was	be	AUX
admet-512	86	8	selected	select	VERB
admet-512	86	9	from	from	ADP
admet-512	86	10	other	other	ADJ
admet-512	86	11	sources	source	NOUN
admet-512	86	12	[	[	X
admet-512	86	13	5,26,27	5,26,27	NUM
admet-512	86	14	]	]	PUNCT
admet-512	86	15	to	to	PART
admet-512	86	16	predict	predict	VERB
admet-512	86	17	the	the	DET
admet-512	86	18	kp	kp	PROPN
admet-512	86	19	values	value	NOUN
admet-512	86	20	from	from	ADP
admet-512	86	21	our	our	PRON
admet-512	86	22	model	model	NOUN
admet-512	86	23	’s	’s	PART
admet-512	86	24	equation	equation	NOUN
admet-512	86	25	and	and	CCONJ
admet-512	86	26	then	then	ADV
admet-512	86	27	compare	compare	VERB
admet-512	86	28	them	they	PRON
admet-512	86	29	to	to	ADP
admet-512	86	30	the	the	DET
admet-512	86	31	available	available	ADJ
admet-512	86	32	literature	literature	PROPN
admet-512	86	33	experimental	experimental	ADJ
admet-512	86	34	and/or	and/or	CCONJ
admet-512	86	35	estimated	estimate	VERB
admet-512	86	36	data	datum	NOUN
admet-512	86	37	.	.	PUNCT
admet-512	87	1	model	model	NOUN
admet-512	87	2	establishment	establishment	NOUN
admet-512	87	3	a	a	DET
admet-512	87	4	correlation	correlation	NOUN
admet-512	87	5	between	between	ADP
admet-512	87	6	the	the	DET
admet-512	87	7	experimental	experimental	ADJ
admet-512	87	8	log	log	NOUN
admet-512	87	9	kp	kp	PROPN
admet-512	87	10	values	value	NOUN
admet-512	87	11	and	and	CCONJ
admet-512	87	12	the	the	DET
admet-512	87	13	parameters	parameter	NOUN
admet-512	87	14	log	log	VERB
admet-512	87	15	k	k	PROPN
admet-512	87	16	and	and	CCONJ
admet-512	87	17	the	the	DET
admet-512	87	18	mcgowan	mcgowan	PROPN
admet-512	87	19	solute	solute	PROPN
admet-512	87	20	’s	’s	PART
admet-512	87	21	volume	volume	NOUN
admet-512	87	22	(	(	PUNCT
admet-512	87	23	v	v	NOUN
admet-512	87	24	)	)	PUNCT
admet-512	87	25	of	of	ADP
admet-512	87	26	the	the	DET
admet-512	87	27	selected	select	VERB
admet-512	87	28	compounds	compound	NOUN
admet-512	87	29	was	be	AUX
admet-512	87	30	performed	perform	VERB
admet-512	87	31	through	through	ADP
admet-512	87	32	a	a	DET
admet-512	87	33	multiple	multiple	ADJ
admet-512	87	34	linear	linear	ADJ
admet-512	87	35	regression	regression	NOUN
admet-512	87	36	analysis	analysis	NOUN
admet-512	87	37	.	.	PUNCT
admet-512	88	1	log	log	NOUN
admet-512	88	2	k	k	PROPN
admet-512	88	3	values	value	NOUN
admet-512	88	4	were	be	AUX
admet-512	88	5	the	the	DET
admet-512	88	6	ones	one	NOUN
admet-512	88	7	measured	measure	VERB
admet-512	88	8	at	at	ADP
admet-512	88	9	a	a	DET
admet-512	88	10	ph	ph	NOUN
admet-512	88	11	in	in	ADP
admet-512	88	12	which	which	PRON
admet-512	88	13	the	the	DET
admet-512	88	14	solutes	solute	NOUN
admet-512	88	15	were	be	AUX
admet-512	88	16	in	in	ADP
admet-512	88	17	the	the	DET
admet-512	88	18	neutral	neutral	ADJ
admet-512	88	19	form	form	NOUN
admet-512	88	20	.	.	PUNCT
admet-512	89	1	the	the	DET
admet-512	89	2	mcgowan	mcgowan	PROPN
admet-512	89	3	volume	volume	NOUN
admet-512	89	4	of	of	ADP
admet-512	89	5	the	the	DET
admet-512	89	6	compounds	compound	NOUN
admet-512	89	7	can	can	AUX
admet-512	89	8	be	be	AUX
admet-512	89	9	easily	easily	ADV
admet-512	89	10	calculated	calculate	VERB
admet-512	89	11	from	from	ADP
admet-512	89	12	the	the	DET
admet-512	89	13	empirical	empirical	ADJ
admet-512	89	14	formula	formula	NOUN
admet-512	89	15	and	and	CCONJ
admet-512	89	16	the	the	DET
admet-512	89	17	number	number	NOUN
admet-512	89	18	of	of	ADP
admet-512	89	19	single	single	ADJ
admet-512	89	20	,	,	PUNCT
admet-512	89	21	double	double	ADJ
admet-512	89	22	,	,	PUNCT
admet-512	89	23	and	and	CCONJ
admet-512	89	24	triple	triple	ADJ
admet-512	89	25	bounds	bound	NOUN
admet-512	89	26	in	in	ADP
admet-512	89	27	the	the	DET
admet-512	89	28	molecule	molecule	NOUN
admet-512	89	29	.	.	PUNCT
admet-512	90	1	compounds	compound	NOUN
admet-512	90	2	with	with	ADP
admet-512	90	3	a	a	DET
admet-512	90	4	standard	standard	ADJ
admet-512	90	5	residual	residual	ADJ
admet-512	90	6	higher	high	ADJ
admet-512	90	7	than	than	ADP
admet-512	90	8	2.5	2.5	NUM
admet-512	90	9	in	in	ADP
admet-512	90	10	absolute	absolute	ADJ
admet-512	90	11	value	value	NOUN
admet-512	90	12	were	be	AUX
admet-512	90	13	considered	consider	VERB
admet-512	90	14	outliers	outlier	NOUN
admet-512	90	15	.	.	PUNCT
admet-512	91	1	model	model	NOUN
admet-512	91	2	validation	validation	NOUN
admet-512	91	3	the	the	DET
admet-512	91	4	model	model	NOUN
admet-512	91	5	required	require	VERB
admet-512	91	6	an	an	DET
admet-512	91	7	internal	internal	ADJ
admet-512	91	8	validation	validation	NOUN
admet-512	91	9	to	to	PART
admet-512	91	10	evaluate	evaluate	VERB
admet-512	91	11	its	its	PRON
admet-512	91	12	robustness	robustness	NOUN
admet-512	91	13	,	,	PUNCT
admet-512	91	14	and	and	CCONJ
admet-512	91	15	an	an	DET
admet-512	91	16	external	external	ADJ
admet-512	91	17	validation	validation	NOUN
admet-512	91	18	to	to	PART
admet-512	91	19	evaluate	evaluate	VERB
admet-512	91	20	its	its	PRON
admet-512	91	21	predictive	predictive	ADJ
admet-512	91	22	ability	ability	NOUN
admet-512	91	23	.	.	PUNCT
admet-512	92	1	to	to	ADP
admet-512	92	2	this	this	DET
admet-512	92	3	aim	aim	NOUN
admet-512	92	4	,	,	PUNCT
admet-512	92	5	the	the	DET
admet-512	92	6	total	total	ADJ
admet-512	92	7	data	datum	NOUN
admet-512	92	8	set	set	VERB
admet-512	92	9	of	of	ADP
admet-512	92	10	65	65	NUM
admet-512	92	11	compounds	compound	NOUN
admet-512	92	12	was	be	AUX
admet-512	92	13	divided	divide	VERB
admet-512	92	14	into	into	ADP
admet-512	92	15	two	two	NUM
admet-512	92	16	sets	set	NOUN
admet-512	92	17	,	,	PUNCT
admet-512	92	18	the	the	DET
admet-512	92	19	training	training	NOUN
admet-512	92	20	set	set	NOUN
admet-512	92	21	for	for	ADP
admet-512	92	22	the	the	DET
admet-512	92	23	internal	internal	ADJ
admet-512	92	24	validation	validation	NOUN
admet-512	92	25	and	and	CCONJ
admet-512	92	26	the	the	DET
admet-512	92	27	test	test	NOUN
admet-512	92	28	set	set	VERB
admet-512	92	29	for	for	ADP
admet-512	92	30	the	the	DET
admet-512	92	31	external	external	ADJ
admet-512	92	32	validation	validation	NOUN
admet-512	92	33	[	[	X
admet-512	92	34	28	28	NUM
admet-512	92	35	]	]	PUNCT
admet-512	92	36	.	.	PUNCT
admet-512	93	1	to	to	PART
admet-512	93	2	construct	construct	VERB
admet-512	93	3	the	the	DET
admet-512	93	4	two	two	NUM
admet-512	93	5	subsets	subset	NOUN
admet-512	93	6	a	a	DET
admet-512	93	7	representation	representation	NOUN
admet-512	93	8	of	of	ADP
admet-512	93	9	scores	score	NOUN
admet-512	93	10	after	after	SCONJ
admet-512	93	11	principal	principal	ADJ
admet-512	93	12	components	component	NOUN
admet-512	93	13	analysis	analysis	NOUN
admet-512	93	14	(	(	PUNCT
admet-512	93	15	pca	pca	NOUN
admet-512	93	16	)	)	PUNCT
admet-512	93	17	was	be	AUX
admet-512	93	18	performed	perform	VERB
admet-512	93	19	based	base	VERB
admet-512	93	20	on	on	ADP
admet-512	93	21	the	the	DET
admet-512	93	22	abraham	abraham	PROPN
admet-512	93	23	’s	’s	PART
admet-512	93	24	molecular	molecular	ADJ
admet-512	93	25	descriptors	descriptor	NOUN
admet-512	93	26	of	of	ADP
admet-512	93	27	the	the	DET
admet-512	93	28	compounds	compound	NOUN
admet-512	93	29	.	.	PUNCT
admet-512	94	1	the	the	DET
admet-512	94	2	scores	score	NOUN
admet-512	94	3	plot	plot	NOUN
admet-512	94	4	distributes	distribute	VERB
admet-512	94	5	the	the	DET
admet-512	94	6	solutes	solute	NOUN
admet-512	94	7	according	accord	VERB
admet-512	94	8	to	to	ADP
admet-512	94	9	their	their	PRON
admet-512	94	10	physicochemical	physicochemical	ADJ
admet-512	94	11	properties	property	NOUN
admet-512	94	12	,	,	PUNCT
admet-512	94	13	so	so	SCONJ
admet-512	94	14	it	it	PRON
admet-512	94	15	is	be	AUX
admet-512	94	16	easier	easy	ADJ
admet-512	94	17	to	to	PART
admet-512	94	18	do	do	VERB
admet-512	94	19	a	a	DET
admet-512	94	20	representative	representative	ADJ
admet-512	94	21	division	division	NOUN
admet-512	94	22	of	of	ADP
admet-512	94	23	the	the	DET
admet-512	94	24	global	global	ADJ
admet-512	94	25	set	set	NOUN
admet-512	94	26	of	of	ADP
admet-512	94	27	compounds	compound	NOUN
admet-512	94	28	into	into	ADP
admet-512	94	29	the	the	DET
admet-512	94	30	two	two	NUM
admet-512	94	31	subsets	subset	NOUN
admet-512	94	32	.	.	PUNCT
admet-512	95	1	the	the	DET
admet-512	95	2	training	training	NOUN
admet-512	95	3	set	set	NOUN
admet-512	95	4	,	,	PUNCT
admet-512	95	5	which	which	PRON
admet-512	95	6	is	be	AUX
admet-512	95	7	aimed	aim	VERB
admet-512	95	8	at	at	ADP
admet-512	95	9	evaluating	evaluate	VERB
admet-512	95	10	the	the	DET
admet-512	95	11	robustness	robustness	NOUN
admet-512	95	12	of	of	ADP
admet-512	95	13	the	the	DET
admet-512	95	14	model	model	NOUN
admet-512	95	15	,	,	PUNCT
admet-512	95	16	usually	usually	ADV
admet-512	95	17	has	have	VERB
admet-512	95	18	around	around	ADV
admet-512	95	19	50	50	NUM
admet-512	95	20	-	-	SYM
admet-512	95	21	70	70	NUM
admet-512	95	22	%	%	NOUN
admet-512	95	23	of	of	ADP
admet-512	95	24	the	the	DET
admet-512	95	25	selected	select	VERB
admet-512	95	26	compounds	compound	NOUN
admet-512	95	27	.	.	PUNCT
admet-512	96	1	the	the	DET
admet-512	96	2	remaining	remain	VERB
admet-512	96	3	compounds	compound	NOUN
admet-512	96	4	are	be	AUX
admet-512	96	5	used	use	VERB
admet-512	96	6	in	in	ADP
admet-512	96	7	the	the	DET
admet-512	96	8	test	test	NOUN
admet-512	96	9	set	set	NOUN
admet-512	96	10	,	,	PUNCT
admet-512	96	11	which	which	PRON
admet-512	96	12	evaluates	evaluate	VERB
admet-512	96	13	the	the	DET
admet-512	96	14	predictive	predictive	ADJ
admet-512	96	15	ability	ability	NOUN
admet-512	96	16	of	of	ADP
admet-512	96	17	the	the	DET
admet-512	96	18	model	model	NOUN
admet-512	96	19	.	.	PUNCT
admet-512	97	1	the	the	DET
admet-512	97	2	correlation	correlation	NOUN
admet-512	97	3	is	be	AUX
admet-512	97	4	repeated	repeat	VERB
admet-512	97	5	only	only	ADV
admet-512	97	6	with	with	ADP
admet-512	97	7	the	the	DET
admet-512	97	8	training	training	NOUN
admet-512	97	9	set	set	VERB
admet-512	97	10	compounds	compound	NOUN
admet-512	97	11	.	.	PUNCT
admet-512	98	1	the	the	DET
admet-512	98	2	results	result	NOUN
admet-512	98	3	of	of	ADP
admet-512	98	4	this	this	DET
admet-512	98	5	second	second	ADJ
admet-512	98	6	correlation	correlation	NOUN
admet-512	98	7	must	must	AUX
admet-512	98	8	be	be	AUX
admet-512	98	9	compared	compare	VERB
admet-512	98	10	to	to	ADP
admet-512	98	11	the	the	DET
admet-512	98	12	global	global	ADJ
admet-512	98	13	correlation	correlation	NOUN
admet-512	98	14	.	.	PUNCT
admet-512	99	1	if	if	SCONJ
admet-512	99	2	the	the	DET
admet-512	99	3	model	model	NOUN
admet-512	99	4	is	be	AUX
admet-512	99	5	robust	robust	ADJ
admet-512	99	6	,	,	PUNCT
admet-512	99	7	the	the	DET
admet-512	99	8	coefficients	coefficient	NOUN
admet-512	99	9	of	of	ADP
admet-512	99	10	both	both	DET
admet-512	99	11	correlations	correlation	NOUN
admet-512	99	12	should	should	AUX
admet-512	99	13	be	be	AUX
admet-512	99	14	similar	similar	ADJ
admet-512	99	15	.	.	PUNCT
admet-512	100	1	traditional	traditional	ADJ
admet-512	100	2	statistical	statistical	ADJ
admet-512	100	3	parameters	parameter	NOUN
admet-512	100	4	such	such	ADJ
admet-512	100	5	as	as	ADP
admet-512	100	6	the	the	DET
admet-512	100	7	determination	determination	NOUN
admet-512	100	8	coefficient	coefficient	NOUN
admet-512	100	9	(	(	PUNCT
admet-512	100	10	r2	r2	PROPN
admet-512	100	11	)	)	PUNCT
admet-512	100	12	,	,	PUNCT
admet-512	100	13	the	the	DET
admet-512	100	14	standard	standard	ADJ
admet-512	100	15	deviation	deviation	NOUN
admet-512	100	16	(	(	PUNCT
admet-512	100	17	sd	sd	NOUN
admet-512	100	18	)	)	PUNCT
admet-512	100	19	,	,	PUNCT
admet-512	100	20	and	and	CCONJ
admet-512	100	21	the	the	DET
admet-512	100	22	f	f	PROPN
admet-512	100	23	statistic	statistic	NOUN
admet-512	100	24	were	be	AUX
admet-512	100	25	also	also	ADV
admet-512	100	26	considered	consider	VERB
admet-512	100	27	to	to	PART
admet-512	100	28	evaluate	evaluate	VERB
admet-512	100	29	the	the	DET
admet-512	100	30	robustness	robustness	NOUN
admet-512	100	31	of	of	ADP
admet-512	100	32	the	the	DET
admet-512	100	33	model	model	NOUN
admet-512	100	34	.	.	PUNCT
admet-512	101	1	additionally	additionally	ADV
admet-512	101	2	,	,	PUNCT
admet-512	101	3	the	the	DET
admet-512	101	4	leave	leave	VERB
admet-512	101	5	-	-	PUNCT
admet-512	101	6	multiple	multiple	NOUN
admet-512	101	7	-	-	PUNCT
admet-512	101	8	out	out	ADP
admet-512	101	9	cross	cross	ADJ
admet-512	101	10	-	-	ADJ
admet-512	101	11	validation	validation	ADJ
admet-512	101	12	coefficient	coefficient	NOUN
admet-512	101	13	,	,	PUNCT
admet-512	101	14	q2	q2	PROPN
admet-512	101	15	lmo	lmo	PROPN
admet-512	102	1	[	[	X
admet-512	102	2	29,30	29,30	NUM
admet-512	102	3	]	]	PUNCT
admet-512	102	4	,	,	PUNCT
admet-512	102	5	was	be	AUX
admet-512	102	6	calculated	calculate	VERB
admet-512	102	7	.	.	PUNCT
admet-512	103	1	this	this	DET
admet-512	103	2	coefficient	coefficient	NOUN
admet-512	103	3	is	be	AUX
admet-512	103	4	a	a	DET
admet-512	103	5	parameter	parameter	NOUN
admet-512	103	6	that	that	PRON
admet-512	103	7	assesses	assess	VERB
admet-512	103	8	how	how	SCONJ
admet-512	103	9	the	the	DET
admet-512	103	10	results	result	NOUN
admet-512	103	11	of	of	ADP
admet-512	103	12	a	a	DET
admet-512	103	13	statistical	statistical	ADJ
admet-512	103	14	analysis	analysis	NOUN
admet-512	103	15	will	will	AUX
admet-512	103	16	generalize	generalize	VERB
admet-512	103	17	to	to	ADP
admet-512	103	18	an	an	DET
admet-512	103	19	independent	independent	ADJ
admet-512	103	20	data	datum	NOUN
admet-512	103	21	set	set	VERB
admet-512	103	22	.	.	PUNCT
admet-512	104	1	the	the	DET
admet-512	104	2	test	test	NOUN
admet-512	104	3	set	set	NOUN
admet-512	104	4	was	be	AUX
admet-512	104	5	used	use	VERB
admet-512	104	6	to	to	PART
admet-512	104	7	perform	perform	VERB
admet-512	104	8	the	the	DET
admet-512	104	9	external	external	ADJ
admet-512	104	10	validation	validation	NOUN
admet-512	104	11	of	of	ADP
admet-512	104	12	the	the	DET
admet-512	104	13	model	model	NOUN
admet-512	104	14	,	,	PUNCT
admet-512	104	15	i.e.	i.e.	X
admet-512	104	16	ensure	ensure	VERB
admet-512	104	17	its	its	PRON
admet-512	104	18	predictive	predictive	ADJ
admet-512	104	19	ability	ability	NOUN
admet-512	104	20	.	.	PUNCT
admet-512	105	1	the	the	DET
admet-512	105	2	external	external	ADJ
admet-512	105	3	validation	validation	NOUN
admet-512	105	4	consists	consist	VERB
admet-512	105	5	in	in	ADP
admet-512	105	6	predicting	predict	VERB
admet-512	105	7	the	the	DET
admet-512	105	8	biological	biological	ADJ
admet-512	105	9	property	property	NOUN
admet-512	105	10	value	value	NOUN
admet-512	105	11	of	of	ADP
admet-512	105	12	the	the	DET
admet-512	105	13	test	test	NOUN
admet-512	105	14	set	set	VERB
admet-512	105	15	compounds	compound	NOUN
admet-512	105	16	with	with	ADP
admet-512	105	17	the	the	DET
admet-512	105	18	training	training	NOUN
admet-512	105	19	set	set	NOUN
admet-512	105	20	equation	equation	NOUN
admet-512	105	21	.	.	PUNCT
admet-512	106	1	then	then	ADV
admet-512	106	2	,	,	PUNCT
admet-512	106	3	predicted	predict	VERB
admet-512	106	4	log	log	PROPN
admet-512	106	5	kp	kp	PROPN
admet-512	106	6	values	value	NOUN
admet-512	106	7	are	be	AUX
admet-512	106	8	plotted	plot	VERB
admet-512	106	9	against	against	ADP
admet-512	106	10	the	the	DET
admet-512	106	11	experimental	experimental	ADJ
admet-512	106	12	values	value	NOUN
admet-512	106	13	.	.	PUNCT
admet-512	107	1	to	to	PART
admet-512	107	2	ensure	ensure	VERB
admet-512	107	3	that	that	SCONJ
admet-512	107	4	the	the	DET
admet-512	107	5	model	model	NOUN
admet-512	107	6	has	have	VERB
admet-512	107	7	a	a	DET
admet-512	107	8	good	good	ADJ
admet-512	107	9	predictive	predictive	ADJ
admet-512	107	10	ability	ability	NOUN
admet-512	107	11	,	,	PUNCT
admet-512	107	12	the	the	DET
admet-512	107	13	slope	slope	NOUN
admet-512	107	14	must	must	AUX
admet-512	107	15	be	be	AUX
admet-512	107	16	close	close	ADJ
admet-512	107	17	to	to	ADP
admet-512	107	18	1	1	NUM
admet-512	107	19	and	and	CCONJ
admet-512	107	20	the	the	DET
admet-512	107	21	origin	origin	NOUN
admet-512	107	22	ordinate	ordinate	VERB
admet-512	107	23	close	close	ADJ
admet-512	107	24	to	to	ADP
admet-512	107	25	0	0	NUM
admet-512	107	26	.	.	PUNCT
admet-512	108	1	results	result	NOUN
admet-512	108	2	and	and	CCONJ
admet-512	108	3	discussion	discussion	NOUN
admet-512	108	4	establishment	establishment	NOUN
admet-512	108	5	of	of	ADP
admet-512	108	6	a	a	DET
admet-512	108	7	model	model	NOUN
admet-512	108	8	to	to	PART
admet-512	108	9	predict	predict	VERB
admet-512	108	10	kp	kp	PROPN
admet-512	108	11	values	value	NOUN
admet-512	108	12	table	table	NOUN
admet-512	108	13	1	1	NUM
admet-512	108	14	shows	show	VERB
admet-512	108	15	the	the	DET
admet-512	108	16	65	65	NUM
admet-512	108	17	compounds	compound	NOUN
admet-512	108	18	selected	select	VERB
admet-512	108	19	to	to	PART
admet-512	108	20	establish	establish	VERB
admet-512	108	21	the	the	DET
admet-512	108	22	model	model	NOUN
admet-512	108	23	,	,	PUNCT
admet-512	108	24	their	their	PRON
admet-512	108	25	experimental	experimental	ADJ
admet-512	108	26	log	log	NOUN
admet-512	108	27	kp	kp	PROPN
admet-512	108	28	values	value	NOUN
admet-512	108	29	,	,	PUNCT
admet-512	108	30	chromatographic	chromatographic	ADJ
admet-512	108	31	retention	retention	NOUN
admet-512	108	32	factors	factor	NOUN
admet-512	108	33	,	,	PUNCT
admet-512	108	34	log	log	VERB
admet-512	108	35	k	k	PROPN
admet-512	108	36	values	value	NOUN
admet-512	108	37	,	,	PUNCT
admet-512	108	38	and	and	CCONJ
admet-512	108	39	mcgowan	mcgowan	PROPN
admet-512	108	40	volumes	volumes	PROPN
admet-512	108	41	,	,	PUNCT
admet-512	108	42	v.	v.	ADP
admet-512	108	43	a	a	DET
admet-512	108	44	multiple	multiple	ADJ
admet-512	108	45	linear	linear	ADJ
admet-512	108	46	regression	regression	NOUN
admet-512	108	47	admet	admet	PROPN
admet-512	108	48	&	&	CCONJ
admet-512	108	49	dmpk	dmpk	PROPN
admet-512	108	50	6(2	6(2	NUM
admet-512	108	51	)	)	PUNCT
admet-512	108	52	(	(	PUNCT
admet-512	108	53	2018	2018	NUM
admet-512	108	54	)	)	PUNCT
admet-512	108	55	140	140	NUM
admet-512	108	56	-	-	SYM
admet-512	108	57	152	152	NUM
admet-512	108	58	estimation	estimation	NOUN
admet-512	108	59	of	of	ADP
admet-512	108	60	skin	skin	NOUN
admet-512	108	61	permeation	permeation	NOUN
admet-512	108	62	by	by	ADP
admet-512	108	63	liquid	liquid	ADJ
admet-512	108	64	chromatography	chromatography	NOUN
admet-512	108	65	doi	doi	NOUN
admet-512	108	66	:	:	PUNCT
admet-512	108	67	10.5599	10.5599	NUM
admet-512	108	68	/	/	SYM
admet-512	108	69	admet.512	admet.512	NOUN
admet-512	108	70	145	145	NUM
admet-512	108	71	analysis	analysis	NOUN
admet-512	108	72	was	be	AUX
admet-512	108	73	done	do	VERB
admet-512	108	74	between	between	ADP
admet-512	108	75	the	the	DET
admet-512	108	76	experimental	experimental	ADJ
admet-512	108	77	log	log	NOUN
admet-512	108	78	kp	kp	PROPN
admet-512	108	79	values	value	NOUN
admet-512	108	80	and	and	CCONJ
admet-512	108	81	the	the	DET
admet-512	108	82	two	two	NUM
admet-512	108	83	parameters	parameter	NOUN
admet-512	108	84	log	log	VERB
admet-512	108	85	k	k	PROPN
admet-512	108	86	and	and	CCONJ
admet-512	108	87	v.	v.	SCONJ
admet-512	108	88	the	the	DET
admet-512	108	89	set	set	NOUN
admet-512	108	90	of	of	ADP
admet-512	108	91	compounds	compound	NOUN
admet-512	108	92	comprises	comprise	VERB
admet-512	108	93	a	a	DET
admet-512	108	94	wide	wide	ADJ
admet-512	108	95	variety	variety	NOUN
admet-512	108	96	of	of	ADP
admet-512	108	97	chemical	chemical	NOUN
admet-512	108	98	classes	class	NOUN
admet-512	108	99	and	and	CCONJ
admet-512	108	100	structural	structural	ADJ
admet-512	108	101	complexity	complexity	NOUN
admet-512	108	102	.	.	PUNCT
admet-512	109	1	this	this	PRON
admet-512	109	2	is	be	AUX
admet-512	109	3	important	important	ADJ
admet-512	109	4	in	in	ADP
admet-512	109	5	order	order	NOUN
admet-512	109	6	to	to	PART
admet-512	109	7	make	make	VERB
admet-512	109	8	the	the	DET
admet-512	109	9	model	model	NOUN
admet-512	109	10	general	general	ADJ
admet-512	109	11	enough	enough	ADV
admet-512	109	12	to	to	PART
admet-512	109	13	predict	predict	VERB
admet-512	109	14	kp	kp	PROPN
admet-512	109	15	values	value	NOUN
admet-512	109	16	of	of	ADP
admet-512	109	17	compounds	compound	NOUN
admet-512	109	18	of	of	ADP
admet-512	109	19	very	very	ADV
admet-512	109	20	different	different	ADJ
admet-512	109	21	chemical	chemical	NOUN
admet-512	109	22	nature	nature	NOUN
admet-512	109	23	.	.	PUNCT
admet-512	110	1	results	result	NOUN
admet-512	110	2	are	be	AUX
admet-512	110	3	shown	show	VERB
admet-512	110	4	in	in	ADP
admet-512	110	5	equation	equation	NOUN
admet-512	110	6	4	4	NUM
admet-512	110	7	and	and	CCONJ
admet-512	110	8	figure	figure	VERB
admet-512	110	9	1	1	NUM
admet-512	110	10	.	.	PUNCT
admet-512	110	11	table	table	NOUN
admet-512	110	12	1	1	NUM
admet-512	110	13	.	.	PUNCT
admet-512	110	14	experimental	experimental	ADJ
admet-512	110	15	log	log	PROPN
admet-512	110	16	kp	kp	PROPN
admet-512	110	17	values	value	NOUN
admet-512	110	18	,	,	PUNCT
admet-512	110	19	log	log	VERB
admet-512	110	20	k	k	PROPN
admet-512	110	21	values	value	NOUN
admet-512	110	22	of	of	ADP
admet-512	110	23	the	the	DET
admet-512	110	24	neutral	neutral	ADJ
admet-512	110	25	species	specie	NOUN
admet-512	110	26	and	and	CCONJ
admet-512	110	27	mcgowan	mcgowan	PROPN
admet-512	110	28	solute	solute	PROPN
admet-512	110	29	’s	’s	PART
admet-512	110	30	volume	volume	NOUN
admet-512	110	31	of	of	ADP
admet-512	110	32	the	the	DET
admet-512	110	33	compounds	compound	NOUN
admet-512	110	34	selected	select	VERB
admet-512	110	35	to	to	PART
admet-512	110	36	establish	establish	VERB
admet-512	110	37	the	the	DET
admet-512	110	38	model	model	NOUN
admet-512	110	39	compounds	compound	NOUN
admet-512	110	40	log	log	VERB
admet-512	110	41	kp	kp	PROPN
admet-512	110	42	log	log	VERB
admet-512	110	43	k	k	PROPN
admet-512	110	44	mcgowans	mcgowans	PROPN
admet-512	110	45	's	's	PART
admet-512	110	46	volume	volume	NOUN
admet-512	110	47	(	(	PUNCT
admet-512	110	48	v	v	NOUN
admet-512	110	49	)	)	PUNCT
admet-512	110	50	2,4	2,4	NUM
admet-512	110	51	-	-	PUNCT
admet-512	110	52	dichlorophenol	dichlorophenol	NOUN
admet-512	110	53	-4.30	-4.30	NUM
admet-512	110	54	0.556	0.556	NUM
admet-512	110	55	1.0199	1.0199	NUM
admet-512	110	56	2	2	NUM
admet-512	110	57	-	-	PUNCT
admet-512	110	58	amino-4	amino-4	NOUN
admet-512	110	59	-	-	PUNCT
admet-512	110	60	nitrophenol	nitrophenol	NOUN
admet-512	110	61	-6.54	-6.54	NOUN
admet-512	110	62	-0.089	-0.089	PROPN
admet-512	110	63	1.0491	1.0491	NUM
admet-512	110	64	2	2	NUM
admet-512	110	65	-	-	PUNCT
admet-512	110	66	chlorophenol	chlorophenol	NOUN
admet-512	110	67	-4.56	-4.56	NOUN
admet-512	110	68	0.237	0.237	NUM
admet-512	110	69	0.8975	0.8975	NUM
admet-512	110	70	2	2	NUM
admet-512	110	71	-	-	PUNCT
admet-512	110	72	hydroxybenzoic	hydroxybenzoic	NOUN
admet-512	110	73	acid	acid	NOUN
admet-512	110	74	(	(	PUNCT
admet-512	110	75	salycilic	salycilic	NOUN
admet-512	110	76	acid	acid	NOUN
admet-512	110	77	)	)	PUNCT
admet-512	110	78	-5.33	-5.33	NUM
admet-512	110	79	0.080	0.080	NUM
admet-512	110	80	0.9904	0.9904	NUM
admet-512	110	81	2	2	NUM
admet-512	110	82	-	-	PUNCT
admet-512	110	83	isopropyl-5	isopropyl-5	NOUN
admet-512	110	84	-	-	PUNCT
admet-512	110	85	methylphenol	methylphenol	NOUN
admet-512	110	86	(	(	PUNCT
admet-512	110	87	thymol	thymol	NOUN
admet-512	110	88	)	)	PUNCT
admet-512	110	89	-4.35	-4.35	NOUN
admet-512	110	90	0.849	0.849	NUM
admet-512	110	91	1.3387	1.3387	NUM
admet-512	110	92	2	2	NUM
admet-512	110	93	-	-	PUNCT
admet-512	110	94	naphtol	naphtol	NOUN
admet-512	110	95	(	(	PUNCT
admet-512	110	96	beta	beta	NOUN
admet-512	110	97	-	-	PUNCT
admet-512	110	98	naphthol	naphthol	NOUN
admet-512	110	99	)	)	PUNCT
admet-512	110	100	-4.65	-4.65	ADP
admet-512	110	101	0.419	0.419	NUM
admet-512	110	102	1.1441	1.1441	NUM
admet-512	110	103	2	2	NUM
admet-512	110	104	-	-	PUNCT
admet-512	110	105	nitrophenol	nitrophenol	NOUN
admet-512	110	106	-4.08	-4.08	NUM
admet-512	110	107	0.343	0.343	NUM
admet-512	110	108	0.9493	0.9493	NUM
admet-512	110	109	2	2	NUM
admet-512	110	110	-	-	PUNCT
admet-512	110	111	nitro	nitro	NOUN
admet-512	110	112	-	-	PUNCT
admet-512	110	113	p	p	NOUN
admet-512	110	114	-	-	PUNCT
admet-512	110	115	phenylenediamine	phenylenediamine	NOUN
admet-512	110	116	-6.66	-6.66	ADP
admet-512	110	117	-0.187	-0.187	PROPN
admet-512	110	118	1.0902	1.0902	NUM
admet-512	110	119	2	2	NUM
admet-512	110	120	-	-	PUNCT
admet-512	110	121	phenylethanol	phenylethanol	NOUN
admet-512	110	122	-5.20	-5.20	NUM
admet-512	110	123	0.003	0.003	NUM
admet-512	110	124	1.0569	1.0569	NUM
admet-512	110	125	3	3	NUM
admet-512	110	126	-	-	PUNCT
admet-512	110	127	methylphenol	methylphenol	NOUN
admet-512	110	128	(	(	PUNCT
admet-512	110	129	m	m	NOUN
admet-512	110	130	-	-	PUNCT
admet-512	110	131	cresol	cresol	NOUN
admet-512	110	132	)	)	PUNCT
admet-512	110	133	-4.89	-4.89	NUM
admet-512	110	134	0.172	0.172	NUM
admet-512	110	135	0.9160	0.9160	NUM
admet-512	110	136	3	3	NUM
admet-512	110	137	-	-	PUNCT
admet-512	110	138	nitrophenol	nitrophenol	NOUN
admet-512	110	139	-5.33	-5.33	NOUN
admet-512	110	140	0.145	0.145	NUM
admet-512	110	141	0.9493	0.9493	NUM
admet-512	110	142	4	4	NUM
admet-512	110	143	-	-	PUNCT
admet-512	110	144	amino-2	amino-2	NUM
admet-512	110	145	-	-	PUNCT
admet-512	110	146	nitrophenol	nitrophenol	NOUN
admet-512	110	147	-5.91	-5.91	NOUN
admet-512	110	148	-0.010	-0.010	X
admet-512	110	149	1.0491	1.0491	NUM
admet-512	110	150	4	4	NUM
admet-512	110	151	-	-	PUNCT
admet-512	110	152	bromophenol	bromophenol	NOUN
admet-512	110	153	-4.52	-4.52	NOUN
admet-512	110	154	0.361	0.361	NUM
admet-512	110	155	0.9501	0.9501	NUM
admet-512	110	156	4	4	NUM
admet-512	110	157	-	-	PUNCT
admet-512	110	158	chloro-3	chloro-3	NUM
admet-512	110	159	-	-	PUNCT
admet-512	110	160	methylphenol	methylphenol	NOUN
admet-512	110	161	(	(	PUNCT
admet-512	110	162	4	4	NUM
admet-512	110	163	-	-	PUNCT
admet-512	110	164	chloro	chloro	NOUN
admet-512	110	165	-	-	PUNCT
admet-512	110	166	m	m	NOUN
admet-512	110	167	-	-	PUNCT
admet-512	110	168	cresol	cresol	NOUN
admet-512	110	169	)	)	PUNCT
admet-512	110	170	-4.34	-4.34	NOUN
admet-512	110	171	0.474	0.474	NUM
admet-512	110	172	1.0384	1.0384	NUM
admet-512	110	173	4	4	NUM
admet-512	110	174	-	-	PUNCT
admet-512	110	175	chlorophenol	chlorophenol	NOUN
admet-512	110	176	-4.52	-4.52	NOUN
admet-512	110	177	0.299	0.299	NUM
admet-512	110	178	0.8975	0.8975	NUM
admet-512	110	179	4	4	NUM
admet-512	110	180	-	-	PUNCT
admet-512	110	181	ethylphenol	ethylphenol	NOUN
admet-512	110	182	-4.53	-4.53	NOUN
admet-512	110	183	0.380	0.380	NUM
admet-512	110	184	1.0569	1.0569	NUM
admet-512	110	185	4	4	NUM
admet-512	110	186	-	-	PUNCT
admet-512	110	187	hydroxybenzyl	hydroxybenzyl	NOUN
admet-512	110	188	alcohol	alcohol	NOUN
admet-512	110	189	-6.26	-6.26	NOUN
admet-512	110	190	-0.560	-0.560	NUM
admet-512	110	191	0.9747	0.9747	NUM
admet-512	110	192	4	4	NUM
admet-512	110	193	-	-	PUNCT
admet-512	110	194	hydroxy	hydroxy	VERB
admet-512	110	195	-	-	PUNCT
admet-512	110	196	methylphenylacetate	methylphenylacetate	NOUN
admet-512	110	197	-5.26	-5.26	ADJ
admet-512	110	198	-0.177	-0.177	PUNCT
admet-512	110	199	1.2722	1.2722	NUM
admet-512	110	200	4	4	NUM
admet-512	110	201	-	-	PUNCT
admet-512	110	202	hydroxyphenylacetamide	hydroxyphenylacetamide	NOUN
admet-512	110	203	-6.89	-6.89	NOUN
admet-512	110	204	-0.606	-0.606	NUM
admet-512	110	205	1.1724	1.1724	NUM
admet-512	110	206	4	4	NUM
admet-512	110	207	-	-	PUNCT
admet-512	110	208	hydroxy	hydroxy	VERB
admet-512	110	209	-	-	PUNCT
admet-512	110	210	phenylacetic	phenylacetic	NOUN
admet-512	110	211	acid	acid	NOUN
admet-512	110	212	-6.06	-6.06	NUM
admet-512	110	213	-0.539	-0.539	PUNCT
admet-512	110	214	1.1313	1.1313	NUM
admet-512	110	215	4	4	NUM
admet-512	110	216	-	-	PUNCT
admet-512	110	217	methylphenol	methylphenol	NOUN
admet-512	110	218	(	(	PUNCT
admet-512	110	219	p	p	NOUN
admet-512	110	220	-	-	PUNCT
admet-512	110	221	cresol	cresol	NOUN
admet-512	110	222	)	)	PUNCT
admet-512	110	223	-4.83	-4.83	ADV
admet-512	110	224	0.169	0.169	NUM
admet-512	110	225	0.9160	0.9160	NUM
admet-512	110	226	4	4	NUM
admet-512	110	227	-	-	PUNCT
admet-512	110	228	nitrophenol	nitrophenol	NOUN
admet-512	110	229	-5.33	-5.33	NUM
admet-512	110	230	0.091	0.091	NUM
admet-512	110	231	0.9493	0.9493	NUM
admet-512	110	232	5,5	5,5	NUM
admet-512	110	233	-	-	PUNCT
admet-512	110	234	diethylbarbituric	diethylbarbituric	ADJ
admet-512	110	235	acid	acid	NOUN
admet-512	110	236	(	(	PUNCT
admet-512	110	237	barbital	barbital	ADJ
admet-512	110	238	)	)	PUNCT
admet-512	110	239	-7.29	-7.29	NOUN
admet-512	110	240	-0.377	-0.377	SYM
admet-512	110	241	1.3739	1.3739	NUM
admet-512	110	242	5	5	NUM
admet-512	110	243	-	-	PUNCT
admet-512	110	244	ethyl-5	ethyl-5	NUM
admet-512	110	245	-	-	PUNCT
admet-512	110	246	phenylbarbituric	phenylbarbituric	NOUN
admet-512	110	247	acid	acid	NOUN
admet-512	110	248	(	(	PUNCT
admet-512	110	249	phenobarbital	phenobarbital	ADJ
admet-512	110	250	)	)	PUNCT
admet-512	110	251	-6.68	-6.68	NUM
admet-512	110	252	-0.059	-0.059	PUNCT
admet-512	111	1	1.6999	1.6999	NUM
admet-512	111	2	5	5	NUM
admet-512	111	3	-	-	PUNCT
admet-512	111	4	fluorouracil	fluorouracil	NOUN
admet-512	111	5	-6.82	-6.82	NUM
admet-512	111	6	-0.977	-0.977	NUM
admet-512	111	7	0.7693	0.7693	NUM
admet-512	111	8	8	8	NUM
admet-512	111	9	-	-	PUNCT
admet-512	111	10	methoxypsoralen	methoxypsoralen	VERB
admet-512	111	11	-5.12	-5.12	NOUN
admet-512	111	12	0.376	0.376	NUM
admet-512	111	13	1.4504	1.4504	NUM
admet-512	111	14	aniline	aniline	NOUN
admet-512	111	15	-4.73	-4.73	NUM
admet-512	111	16	0.018	0.018	NUM
admet-512	111	17	0.8162	0.8162	NUM
admet-512	111	18	aspirin	aspirin	NOUN
admet-512	111	19	(	(	PUNCT
admet-512	111	20	acetylsalicylic	acetylsalicylic	NOUN
admet-512	111	21	acid	acid	NOUN
admet-512	111	22	)	)	PUNCT
admet-512	111	23	-5.69	-5.69	VERB
admet-512	111	24	-0.165	-0.165	NOUN
admet-512	111	25	1.2879	1.2879	NUM
admet-512	111	26	atropine	atropine	NOUN
admet-512	111	27	-7.15	-7.15	VERB
admet-512	111	28	0.551	0.551	NUM
admet-512	111	29	2.2820	2.2820	NUM
admet-512	111	30	benzaldehyde	benzaldehyde	NOUN
admet-512	111	31	-3.93	-3.93	NUM
admet-512	111	32	0.221	0.221	NUM
admet-512	111	33	0.8730	0.8730	NUM
admet-512	111	34	benzene	benzene	NOUN
admet-512	111	35	-4.27	-4.27	NOUN
admet-512	111	36	0.587	0.587	NUM
admet-512	111	37	0.7164	0.7164	NUM
admet-512	111	38	benzoic	benzoic	NOUN
admet-512	111	39	acid	acid	NOUN
admet-512	111	40	-5.15	-5.15	NOUN
admet-512	111	41	-0.073	-0.073	PUNCT
admet-512	111	42	0.9317	0.9317	NUM
admet-512	111	43	benzyl	benzyl	NOUN
admet-512	111	44	alcohol	alcohol	NOUN
admet-512	111	45	-5.30	-5.30	PART
admet-512	111	46	-0.113	-0.113	NOUN
admet-512	111	47	0.9160	0.9160	NUM
admet-512	111	48	benzyl	benzyl	NOUN
admet-512	111	49	nicotinate	nicotinate	NOUN
admet-512	111	50	-4.87	-4.87	NUM
admet-512	111	51	0.569	0.569	NUM
admet-512	111	52	1.6393	1.6393	NUM
admet-512	111	53	caffeine	caffeine	NOUN
admet-512	111	54	-7.08	-7.08	ADP
admet-512	111	55	-0.487	-0.487	PROPN
admet-512	111	56	1.3632	1.3632	NUM
admet-512	111	57	chloropheniramine	chloropheniramine	NOUN
admet-512	111	58	-6.14	-6.14	PROPN
admet-512	112	1	1.009	1.009	NUM
admet-512	112	2	2.2098	2.2098	NUM
admet-512	112	3	marti	marti	PROPN
admet-512	112	4	rosés	rosé	NOUN
admet-512	112	5	et	et	PROPN
admet-512	112	6	al	al	PROPN
admet-512	112	7	admet	admet	PROPN
admet-512	112	8	&	&	CCONJ
admet-512	112	9	dmpk	dmpk	PROPN
admet-512	112	10	6(2	6(2	NUM
admet-512	112	11	)	)	PUNCT
admet-512	112	12	(	(	PUNCT
admet-512	112	13	2018	2018	NUM
admet-512	112	14	)	)	PUNCT
admet-512	112	15	140	140	NUM
admet-512	112	16	-	-	SYM
admet-512	112	17	152	152	NUM
admet-512	112	18	146	146	NUM
admet-512	112	19	table	table	NOUN
admet-512	112	20	1	1	NUM
admet-512	112	21	.	.	NUM
admet-512	112	22	continued	continue	VERB
admet-512	112	23	…	…	PUNCT
admet-512	112	24	compounds	compound	VERB
admet-512	112	25	log	log	VERB
admet-512	112	26	kp	kp	PROPN
admet-512	112	27	log	log	VERB
admet-512	112	28	k	k	PROPN
admet-512	112	29	mcgowans	mcgowans	PROPN
admet-512	112	30	's	's	PART
admet-512	112	31	volume	volume	NOUN
admet-512	112	32	(	(	PUNCT
admet-512	112	33	v	v	NOUN
admet-512	112	34	)	)	PUNCT
admet-512	112	35	codeine	codeine	NOUN
admet-512	112	36	-7.20	-7.20	NUM
admet-512	112	37	0.116	0.116	NUM
admet-512	112	38	2.2057	2.2057	NUM
admet-512	112	39	corticosterone	corticosterone	NOUN
admet-512	112	40	-6.84	-6.84	ADP
admet-512	112	41	0.230	0.230	NUM
admet-512	112	42	2.7389	2.7389	NUM
admet-512	112	43	dexamethasone	dexamethasone	NOUN
admet-512	112	44	-7.27	-7.27	NOUN
admet-512	112	45	0.172	0.172	NUM
admet-512	112	46	2.9132	2.9132	NUM
admet-512	112	47	diclofenac	diclofenac	NOUN
admet-512	112	48	-5.30	-5.30	VERB
admet-512	112	49	0.995	0.995	NUM
admet-512	112	50	2.0250	2.0250	NUM
admet-512	112	51	diethylcarbamazine	diethylcarbamazine	NOUN
admet-512	112	52	-6.15	-6.15	NOUN
admet-512	112	53	-0.049	-0.049	PUNCT
admet-512	112	54	1.7241	1.7241	NUM
admet-512	112	55	digitoxin	digitoxin	PROPN
admet-512	112	56	-8.15	-8.15	NUM
admet-512	112	57	0.642	0.642	NUM
admet-512	112	58	5.6938	5.6938	NUM
admet-512	112	59	ephedrine	ephedrine	NOUN
admet-512	112	60	-5.49	-5.49	ADP
admet-512	112	61	0.314	0.314	NUM
admet-512	112	62	1.4385	1.4385	NUM
admet-512	112	63	estradiol	estradiol	PROPN
admet-512	112	64	-5.61	-5.61	NUM
admet-512	112	65	0.534	0.534	NUM
admet-512	112	66	2.1988	2.1988	NUM
admet-512	112	67	ethylbenzene	ethylbenzene	NOUN
admet-512	112	68	-3.00	-3.00	NUM
admet-512	112	69	1.065	1.065	NUM
admet-512	112	70	0.9982	0.9982	NUM
admet-512	112	71	fentanyl	fentanyl	ADJ
admet-512	112	72	-4.89	-4.89	NUM
admet-512	112	73	1.144	1.144	NUM
admet-512	112	74	2.8399	2.8399	NUM
admet-512	112	75	fluocinonide	fluocinonide	NOUN
admet-512	112	76	-6.33	-6.33	NUM
admet-512	112	77	0.904	0.904	NUM
admet-512	112	78	3.4603	3.4603	NUM
admet-512	112	79	hydrocortisone	hydrocortisone	NOUN
admet-512	112	80	-7.22	-7.22	NOUN
admet-512	112	81	-0.055	-0.055	PROPN
admet-512	112	82	2.7976	2.7976	NUM
admet-512	112	83	ibuprofen	ibuprofen	NOUN
admet-512	112	84	-5.30	-5.30	NUM
admet-512	112	85	1.007	1.007	NUM
admet-512	112	86	1.7771	1.7771	NUM
admet-512	112	87	indomethacin	indomethacin	VERB
admet-512	112	88	-5.39	-5.39	VERB
admet-512	112	89	1.001	1.001	NUM
admet-512	112	90	2.5299	2.5299	NUM
admet-512	112	91	isoquinoline	isoquinoline	ADJ
admet-512	112	92	-5.11	-5.11	NOUN
admet-512	112	93	0.220	0.220	NUM
admet-512	112	94	1.0443	1.0443	NUM
admet-512	112	95	lidocaine	lidocaine	NOUN
admet-512	112	96	-5.42	-5.42	NUM
admet-512	112	97	0.764	0.764	NUM
admet-512	112	98	2.0589	2.0589	NUM
admet-512	112	99	methyl	methyl	NOUN
admet-512	112	100	4	4	NUM
admet-512	112	101	-	-	PUNCT
admet-512	112	102	hydroxybenzoate	hydroxybenzoate	NOUN
admet-512	112	103	-5.12	-5.12	NUM
admet-512	112	104	0.002	0.002	NUM
admet-512	112	105	1.1313	1.1313	NUM
admet-512	112	106	methyl	methyl	NOUN
admet-512	112	107	phenyl	phenyl	NOUN
admet-512	112	108	ether	ether	NOUN
admet-512	112	109	(	(	PUNCT
admet-512	112	110	anisole	anisole	NOUN
admet-512	112	111	)	)	PUNCT
admet-512	112	112	-4.68	-4.68	VERB
admet-512	112	113	0.543	0.543	NUM
admet-512	112	114	0.9160	0.9160	NUM
admet-512	112	115	naproxen	naproxen	NOUN
admet-512	112	116	-4.97	-4.97	VERB
admet-512	112	117	0.557	0.557	NUM
admet-512	112	118	1.7821	1.7821	NUM
admet-512	112	119	nicotine	nicotine	NOUN
admet-512	112	120	-6.03	-6.03	NUM
admet-512	112	121	0.061	0.061	NUM
admet-512	112	122	1.3710	1.3710	NUM
admet-512	112	123	o	o	NOUN
admet-512	112	124	-	-	NOUN
admet-512	112	125	phenylenediamine	phenylenediamine	ADJ
admet-512	112	126	-6.70	-6.70	PROPN
admet-512	112	127	-0.313	-0.313	PUNCT
admet-512	112	128	0.9160	0.9160	NUM
admet-512	112	129	phenol	phenol	NOUN
admet-512	112	130	-5.27	-5.27	ADJ
admet-512	112	131	-0.006	-0.006	PROPN
admet-512	112	132	0.7751	0.7751	NUM
admet-512	112	133	p	p	NOUN
admet-512	112	134	-	-	PUNCT
admet-512	112	135	phenylenediamine	phenylenediamine	NOUN
admet-512	112	136	-6.98	-6.98	NOUN
admet-512	112	137	-0.415	-0.415	NUM
admet-512	113	1	0.9160	0.9160	NUM
admet-512	113	2	progesterone	progesterone	NOUN
admet-512	113	3	-4.90	-4.90	NOUN
admet-512	113	4	1.130	1.130	NUM
admet-512	113	5	2.6215	2.6215	NUM
admet-512	113	6	resorcinol	resorcinol	NOUN
admet-512	113	7	-6.70	-6.70	NUM
admet-512	113	8	-0.412	-0.412	NOUN
admet-512	113	9	0.8338	0.8338	NUM
admet-512	113	10	scopolamine	scopolamine	NOUN
admet-512	113	11	-7.90	-7.90	NUM
admet-512	113	12	-0.036	-0.036	SYM
admet-512	113	13	2.2321	2.2321	NUM
admet-512	113	14	sufentanil	sufentanil	NOUN
admet-512	113	15	-4.84	-4.84	NUM
admet-512	113	16	1.379	1.379	NUM
admet-512	113	17	3.1051	3.1051	NUM
admet-512	113	18	testosterone	testosterone	NOUN
admet-512	113	19	-5.54	-5.54	NOUN
admet-512	113	20	0.557	0.557	NUM
admet-512	113	21	2.3827	2.3827	NUM
admet-512	113	22	toluene	toluene	NOUN
admet-512	113	23	-3.64	-3.64	NUM
admet-512	113	24	0.826	0.826	NUM
admet-512	113	25	0.8573	0.8573	NUM
admet-512	113	26	log	log	PROPN
admet-512	113	27	kp=	kp=	PROPN
admet-512	113	28	4.47(±0.12	4.47(±0.12	NUM
admet-512	113	29	)	)	PUNCT
admet-512	114	1	+	+	SYM
admet-512	114	2	1.98(±0.13	1.98(±0.13	X
admet-512	114	3	)	)	PUNCT
admet-512	114	4	log	log	VERB
admet-512	114	5	k	k	PROPN
admet-512	114	6	1.02(±0.07	1.02(±0.07	X
admet-512	114	7	)	)	PUNCT
admet-512	114	8	v	v	NOUN
admet-512	114	9	(	(	PUNCT
admet-512	114	10	4	4	NUM
admet-512	114	11	)	)	PUNCT
admet-512	114	12	n	n	NOUN
admet-512	114	13	=	=	SYM
admet-512	114	14	63	63	NUM
admet-512	114	15	r2	r2	NOUN
admet-512	114	16	=	=	PUNCT
admet-512	114	17	0.826	0.826	NUM
admet-512	114	18	sd	sd	ADP
admet-512	114	19	=	=	PUNCT
admet-512	114	20	0.461	0.461	NUM
admet-512	114	21	f	f	NOUN
admet-512	114	22	=	=	SYM
admet-512	114	23	143	143	NUM
admet-512	114	24	from	from	ADP
admet-512	114	25	the	the	DET
admet-512	114	26	65	65	NUM
admet-512	114	27	substances	substance	NOUN
admet-512	114	28	,	,	PUNCT
admet-512	114	29	only	only	ADV
admet-512	114	30	atropine	atropine	NOUN
admet-512	114	31	and	and	CCONJ
admet-512	114	32	chloropheniramine	chloropheniramine	NOUN
admet-512	114	33	were	be	AUX
admet-512	114	34	excluded	exclude	VERB
admet-512	114	35	from	from	ADP
admet-512	114	36	the	the	DET
admet-512	114	37	regression	regression	NOUN
admet-512	114	38	analysis	analysis	NOUN
admet-512	114	39	because	because	SCONJ
admet-512	114	40	their	their	PRON
admet-512	114	41	standard	standard	ADJ
admet-512	114	42	residuals	residual	NOUN
admet-512	114	43	were	be	AUX
admet-512	114	44	greater	great	ADJ
admet-512	114	45	than	than	ADP
admet-512	114	46	2.5	2.5	NUM
admet-512	114	47	in	in	ADP
admet-512	114	48	absolute	absolute	ADJ
admet-512	114	49	value	value	NOUN
admet-512	114	50	.	.	PUNCT
admet-512	115	1	both	both	DET
admet-512	115	2	coefficients	coefficient	NOUN
admet-512	115	3	in	in	ADP
admet-512	115	4	equation	equation	NOUN
admet-512	115	5	4	4	NUM
admet-512	115	6	have	have	VERB
admet-512	115	7	statistical	statistical	ADJ
admet-512	115	8	meaning	meaning	NOUN
admet-512	115	9	at	at	ADP
admet-512	115	10	a	a	DET
admet-512	115	11	95	95	NUM
admet-512	115	12	%	%	NOUN
admet-512	115	13	level	level	NOUN
admet-512	115	14	of	of	ADP
admet-512	115	15	confidence	confidence	NOUN
admet-512	115	16	,	,	PUNCT
admet-512	115	17	and	and	CCONJ
admet-512	115	18	log	log	NOUN
admet-512	115	19	k	k	PROPN
admet-512	115	20	has	have	VERB
admet-512	115	21	the	the	DET
admet-512	115	22	highest	high	ADJ
admet-512	115	23	contribution	contribution	NOUN
admet-512	115	24	to	to	ADP
admet-512	115	25	skin	skin	NOUN
admet-512	115	26	permeation	permeation	NOUN
admet-512	115	27	.	.	PUNCT
admet-512	116	1	note	note	VERB
admet-512	116	2	that	that	SCONJ
admet-512	116	3	the	the	DET
admet-512	116	4	log	log	NOUN
admet-512	116	5	k	k	PROPN
admet-512	116	6	coefficient	coefficient	NOUN
admet-512	116	7	is	be	AUX
admet-512	116	8	almost	almost	ADV
admet-512	116	9	twice	twice	ADV
admet-512	116	10	in	in	ADP
admet-512	116	11	absolute	absolute	ADJ
admet-512	116	12	value	value	NOUN
admet-512	116	13	the	the	DET
admet-512	116	14	v	v	NOUN
admet-512	116	15	coefficient	coefficient	NOUN
admet-512	116	16	.	.	PUNCT
admet-512	117	1	log	log	PROPN
admet-512	117	2	k	k	PROPN
admet-512	117	3	contributes	contribute	VERB
admet-512	117	4	in	in	ADP
admet-512	117	5	a	a	DET
admet-512	117	6	positive	positive	ADJ
admet-512	117	7	way	way	NOUN
admet-512	117	8	,	,	PUNCT
admet-512	117	9	which	which	PRON
admet-512	117	10	suggests	suggest	VERB
admet-512	117	11	that	that	SCONJ
admet-512	117	12	a	a	DET
admet-512	117	13	high	high	ADJ
admet-512	117	14	retention	retention	NOUN
admet-512	117	15	factor	factor	NOUN
admet-512	117	16	implies	imply	VERB
admet-512	117	17	a	a	DET
admet-512	117	18	better	well	ADJ
admet-512	117	19	dermal	dermal	ADJ
admet-512	117	20	absorption	absorption	NOUN
admet-512	117	21	.	.	PUNCT
admet-512	118	1	the	the	DET
admet-512	118	2	v	v	PROPN
admet-512	118	3	coefficient	coefficient	NOUN
admet-512	118	4	applies	apply	VERB
admet-512	118	5	a	a	DET
admet-512	118	6	negative	negative	ADJ
admet-512	118	7	correction	correction	NOUN
admet-512	118	8	to	to	ADP
admet-512	118	9	the	the	DET
admet-512	118	10	log	log	NOUN
admet-512	118	11	kp	kp	PROPN
admet-512	118	12	value	value	NOUN
admet-512	118	13	,	,	PUNCT
admet-512	118	14	more	more	ADV
admet-512	118	15	important	important	ADJ
admet-512	118	16	for	for	ADP
admet-512	118	17	those	those	DET
admet-512	118	18	compounds	compound	NOUN
admet-512	118	19	with	with	ADP
admet-512	118	20	higher	high	ADJ
admet-512	118	21	volume	volume	NOUN
admet-512	118	22	.	.	PUNCT
admet-512	119	1	equation	equation	NOUN
admet-512	119	2	(	(	PUNCT
admet-512	119	3	4	4	X
admet-512	119	4	)	)	PUNCT
admet-512	119	5	is	be	AUX
admet-512	119	6	very	very	ADV
admet-512	119	7	similar	similar	ADJ
admet-512	119	8	to	to	ADP
admet-512	119	9	the	the	DET
admet-512	119	10	previous	previous	ADJ
admet-512	119	11	equation	equation	NOUN
admet-512	119	12	(	(	PUNCT
admet-512	119	13	2	2	NUM
admet-512	119	14	)	)	PUNCT
admet-512	119	15	.	.	PUNCT
admet-512	120	1	direct	direct	ADJ
admet-512	120	2	comparison	comparison	NOUN
admet-512	120	3	of	of	ADP
admet-512	120	4	the	the	DET
admet-512	120	5	parameters	parameter	NOUN
admet-512	120	6	in	in	ADP
admet-512	120	7	both	both	DET
admet-512	120	8	cases	case	NOUN
admet-512	120	9	reveals	reveal	VERB
admet-512	120	10	almost	almost	ADV
admet-512	120	11	the	the	DET
admet-512	120	12	same	same	ADJ
admet-512	120	13	values	value	NOUN
admet-512	120	14	for	for	ADP
admet-512	120	15	the	the	DET
admet-512	120	16	v	v	NOUN
admet-512	120	17	coefficient	coefficient	NOUN
admet-512	120	18	and	and	CCONJ
admet-512	120	19	the	the	DET
admet-512	120	20	intercept	intercept	NOUN
admet-512	120	21	,	,	PUNCT
admet-512	120	22	and	and	CCONJ
admet-512	120	23	only	only	ADV
admet-512	120	24	a	a	DET
admet-512	120	25	slight	slight	ADJ
admet-512	120	26	difference	difference	NOUN
admet-512	120	27	in	in	ADP
admet-512	120	28	the	the	DET
admet-512	120	29	log	log	NOUN
admet-512	120	30	k	k	PROPN
admet-512	120	31	coefficient	coefficient	PROPN
admet-512	120	32	.	.	PUNCT
admet-512	121	1	this	this	DET
admet-512	121	2	difference	difference	NOUN
admet-512	121	3	is	be	AUX
admet-512	121	4	mainly	mainly	ADV
admet-512	121	5	attributed	attribute	VERB
admet-512	121	6	to	to	ADP
admet-512	121	7	the	the	DET
admet-512	121	8	number	number	NOUN
admet-512	121	9	and	and	CCONJ
admet-512	121	10	variety	variety	NOUN
admet-512	121	11	of	of	ADP
admet-512	121	12	compounds	compound	NOUN
admet-512	121	13	studied	study	VERB
admet-512	121	14	.	.	PUNCT
admet-512	122	1	since	since	SCONJ
admet-512	122	2	the	the	DET
admet-512	122	3	present	present	ADJ
admet-512	122	4	work	work	NOUN
admet-512	122	5	covers	cover	VERB
admet-512	122	6	a	a	DET
admet-512	122	7	larger	large	ADJ
admet-512	122	8	number	number	NOUN
admet-512	122	9	of	of	ADP
admet-512	122	10	compounds	compound	NOUN
admet-512	122	11	and	and	CCONJ
admet-512	122	12	they	they	PRON
admet-512	122	13	are	be	AUX
admet-512	122	14	more	more	ADV
admet-512	122	15	representative	representative	NOUN
admet-512	122	16	of	of	ADP
admet-512	122	17	a	a	DET
admet-512	122	18	wide	wide	ADJ
admet-512	122	19	chemical	chemical	NOUN
admet-512	122	20	space	space	NOUN
admet-512	122	21	,	,	PUNCT
admet-512	122	22	it	it	PRON
admet-512	122	23	is	be	AUX
admet-512	122	24	considered	consider	VERB
admet-512	122	25	that	that	SCONJ
admet-512	122	26	equation	equation	NOUN
admet-512	122	27	4	4	NUM
admet-512	122	28	might	might	AUX
admet-512	122	29	be	be	AUX
admet-512	122	30	more	more	ADV
admet-512	122	31	robust	robust	ADJ
admet-512	122	32	than	than	ADP
admet-512	122	33	eq	eq	ADJ
admet-512	122	34	.	.	PROPN
admet-512	122	35	2	2	X
admet-512	122	36	.	.	X
admet-512	122	37	admet	admet	PROPN
admet-512	122	38	&	&	CCONJ
admet-512	122	39	dmpk	dmpk	PROPN
admet-512	122	40	6(2	6(2	NUM
admet-512	122	41	)	)	PUNCT
admet-512	122	42	(	(	PUNCT
admet-512	122	43	2018	2018	NUM
admet-512	122	44	)	)	PUNCT
admet-512	122	45	140	140	NUM
admet-512	122	46	-	-	SYM
admet-512	122	47	152	152	NUM
admet-512	122	48	estimation	estimation	NOUN
admet-512	122	49	of	of	ADP
admet-512	122	50	skin	skin	NOUN
admet-512	122	51	permeation	permeation	NOUN
admet-512	122	52	by	by	ADP
admet-512	122	53	liquid	liquid	ADJ
admet-512	122	54	chromatography	chromatography	NOUN
admet-512	122	55	doi	doi	NOUN
admet-512	122	56	:	:	PUNCT
admet-512	122	57	10.5599	10.5599	NUM
admet-512	122	58	/	/	SYM
admet-512	122	59	admet.512	admet.512	NOUN
admet-512	122	60	147	147	NUM
admet-512	122	61	figure	figure	NOUN
admet-512	122	62	1	1	NUM
admet-512	122	63	.	.	PUNCT
admet-512	122	64	correlation	correlation	NOUN
admet-512	122	65	between	between	ADP
admet-512	122	66	log	log	PROPN
admet-512	122	67	kp	kp	PROPN
admet-512	122	68	experimental	experimental	ADJ
admet-512	122	69	values	value	NOUN
admet-512	122	70	and	and	CCONJ
admet-512	122	71	log	log	VERB
admet-512	122	72	k	k	PROPN
admet-512	122	73	and	and	CCONJ
admet-512	122	74	v	v	NOUN
admet-512	122	75	of	of	ADP
admet-512	122	76	the	the	DET
admet-512	122	77	set	set	NOUN
admet-512	122	78	of	of	ADP
admet-512	122	79	65	65	NUM
admet-512	122	80	compounds	compound	NOUN
admet-512	122	81	selected	select	VERB
admet-512	122	82	to	to	PART
admet-512	122	83	establish	establish	VERB
admet-512	122	84	the	the	DET
admet-512	122	85	model	model	NOUN
admet-512	122	86	as	as	SCONJ
admet-512	122	87	described	describe	VERB
admet-512	122	88	previously	previously	ADV
admet-512	122	89	,	,	PUNCT
admet-512	122	90	to	to	PART
admet-512	122	91	validate	validate	VERB
admet-512	122	92	the	the	DET
admet-512	122	93	model	model	NOUN
admet-512	122	94	,	,	PUNCT
admet-512	122	95	the	the	DET
admet-512	122	96	global	global	ADJ
admet-512	122	97	set	set	NOUN
admet-512	122	98	of	of	ADP
admet-512	122	99	63	63	NUM
admet-512	122	100	compounds	compound	NOUN
admet-512	122	101	was	be	AUX
admet-512	122	102	divided	divide	VERB
admet-512	122	103	into	into	ADP
admet-512	122	104	two	two	NUM
admet-512	122	105	sets	set	NOUN
admet-512	122	106	:	:	PUNCT
admet-512	122	107	the	the	DET
admet-512	122	108	training	training	NOUN
admet-512	122	109	set	set	NOUN
admet-512	122	110	(	(	PUNCT
admet-512	122	111	42	42	NUM
admet-512	122	112	compounds	compound	NOUN
admet-512	122	113	)	)	PUNCT
admet-512	122	114	and	and	CCONJ
admet-512	122	115	the	the	DET
admet-512	122	116	test	test	NOUN
admet-512	122	117	set	set	NOUN
admet-512	122	118	(	(	PUNCT
admet-512	122	119	21	21	NUM
admet-512	122	120	compounds	compound	NOUN
admet-512	122	121	)	)	PUNCT
admet-512	122	122	.	.	PUNCT
admet-512	123	1	a	a	DET
admet-512	123	2	multiple	multiple	ADJ
admet-512	123	3	linear	linear	ADJ
admet-512	123	4	regression	regression	NOUN
admet-512	123	5	between	between	ADP
admet-512	123	6	experimental	experimental	ADJ
admet-512	123	7	log	log	NOUN
admet-512	123	8	kp	kp	PROPN
admet-512	123	9	values	value	NOUN
admet-512	123	10	and	and	CCONJ
admet-512	123	11	log	log	VERB
admet-512	123	12	k	k	PROPN
admet-512	123	13	and	and	CCONJ
admet-512	123	14	v	v	NOUN
admet-512	123	15	was	be	AUX
admet-512	123	16	performed	perform	VERB
admet-512	123	17	with	with	ADP
admet-512	123	18	the	the	DET
admet-512	123	19	42	42	NUM
admet-512	123	20	compounds	compound	NOUN
admet-512	123	21	of	of	ADP
admet-512	123	22	the	the	DET
admet-512	123	23	training	training	NOUN
admet-512	123	24	set	set	NOUN
admet-512	123	25	.	.	PUNCT
admet-512	124	1	equation	equation	NOUN
admet-512	124	2	5	5	NUM
admet-512	124	3	and	and	CCONJ
admet-512	124	4	figure	figure	NOUN
admet-512	124	5	2a	2a	NUM
admet-512	124	6	show	show	VERB
admet-512	124	7	the	the	DET
admet-512	124	8	results	result	NOUN
admet-512	124	9	of	of	ADP
admet-512	124	10	the	the	DET
admet-512	124	11	regression	regression	NOUN
admet-512	124	12	.	.	PUNCT
admet-512	125	1	log	log	VERB
admet-512	125	2	kp=	kp=	PROPN
admet-512	125	3	4.57(±0.13	4.57(±0.13	NUM
admet-512	125	4	)	)	PUNCT
admet-512	126	1	+	+	CCONJ
admet-512	126	2	2.06(±0.17)log	2.06(±0.17)log	NUM
admet-512	126	3	k	k	NOUN
admet-512	126	4	0.98(±0.08	0.98(±0.08	ADJ
admet-512	126	5	)	)	PUNCT
admet-512	126	6	v	v	NOUN
admet-512	126	7	(	(	PUNCT
admet-512	126	8	5	5	NUM
admet-512	126	9	)	)	PUNCT
admet-512	126	10	n	n	NOUN
admet-512	126	11	=	=	SYM
admet-512	126	12	42	42	NUM
admet-512	126	13	r	r	NOUN
admet-512	126	14	2	2	NUM
admet-512	126	15	=	=	SYM
admet-512	126	16	0.832	0.832	NUM
admet-512	126	17	sd	sd	NOUN
admet-512	126	18	=	=	SYM
admet-512	126	19	0.450	0.450	NUM
admet-512	126	20	f	f	X
admet-512	126	21	=	=	SYM
admet-512	126	22	97	97	NUM
admet-512	126	23	q	q	NOUN
admet-512	126	24	2	2	NUM
admet-512	126	25	lmo=0.832	lmo=0.832	NOUN
admet-512	126	26	figure	figure	NOUN
admet-512	126	27	2	2	NUM
admet-512	126	28	.	.	PUNCT
admet-512	127	1	(	(	PUNCT
admet-512	127	2	a	a	X
admet-512	127	3	)	)	PUNCT
admet-512	127	4	correlation	correlation	NOUN
admet-512	127	5	between	between	ADP
admet-512	127	6	log	log	PROPN
admet-512	127	7	kp	kp	PROPN
admet-512	127	8	experimental	experimental	ADJ
admet-512	127	9	values	value	NOUN
admet-512	127	10	and	and	CCONJ
admet-512	127	11	log	log	VERB
admet-512	127	12	k	k	PROPN
admet-512	127	13	and	and	CCONJ
admet-512	127	14	v	v	NOUN
admet-512	127	15	of	of	ADP
admet-512	127	16	the	the	DET
admet-512	127	17	set	set	NOUN
admet-512	127	18	of	of	ADP
admet-512	127	19	compounds	compound	NOUN
admet-512	127	20	selected	select	VERB
admet-512	127	21	in	in	ADP
admet-512	127	22	the	the	DET
admet-512	127	23	training	training	NOUN
admet-512	127	24	set	set	NOUN
admet-512	127	25	.	.	PUNCT
admet-512	128	1	(	(	PUNCT
admet-512	128	2	b	b	X
admet-512	128	3	)	)	PUNCT
admet-512	128	4	estimated	estimate	VERB
admet-512	128	5	vs.	vs.	ADP
admet-512	128	6	experimental	experimental	ADJ
admet-512	128	7	log	log	NOUN
admet-512	128	8	kp	kp	PROPN
admet-512	128	9	values	value	NOUN
admet-512	128	10	for	for	ADP
admet-512	128	11	the	the	DET
admet-512	128	12	compounds	compound	NOUN
admet-512	128	13	of	of	ADP
admet-512	128	14	the	the	DET
admet-512	128	15	test	test	NOUN
admet-512	128	16	set	set	VERB
admet-512	128	17	comparison	comparison	NOUN
admet-512	128	18	of	of	ADP
admet-512	128	19	the	the	DET
admet-512	128	20	intercept	intercept	NOUN
admet-512	128	21	and	and	CCONJ
admet-512	128	22	the	the	DET
admet-512	128	23	coefficients	coefficient	NOUN
admet-512	128	24	of	of	ADP
admet-512	128	25	eq	eq	NOUN
admet-512	128	26	.	.	PROPN
admet-512	128	27	5	5	NUM
admet-512	128	28	to	to	ADP
admet-512	128	29	those	those	PRON
admet-512	128	30	of	of	ADP
admet-512	128	31	eq	eq	PROPN
admet-512	128	32	.	.	PROPN
admet-512	128	33	4	4	NUM
admet-512	128	34	demonstrate	demonstrate	VERB
admet-512	128	35	that	that	SCONJ
admet-512	128	36	nearly	nearly	ADV
admet-512	128	37	the	the	DET
admet-512	128	38	same	same	ADJ
admet-512	128	39	equation	equation	NOUN
admet-512	128	40	is	be	AUX
admet-512	128	41	obtained	obtain	VERB
admet-512	128	42	with	with	ADP
admet-512	128	43	less	less	ADJ
admet-512	128	44	compounds	compound	NOUN
admet-512	128	45	,	,	PUNCT
admet-512	128	46	which	which	PRON
admet-512	128	47	means	mean	VERB
admet-512	128	48	that	that	SCONJ
admet-512	128	49	the	the	DET
admet-512	128	50	model	model	NOUN
admet-512	128	51	is	be	AUX
admet-512	128	52	robust	robust	ADJ
admet-512	128	53	,	,	PUNCT
admet-512	128	54	i.e.	i.e.	X
admet-512	128	55	with	with	ADP
admet-512	128	56	fewer	few	ADJ
admet-512	128	57	points	point	NOUN
admet-512	128	58	the	the	DET
admet-512	128	59	physical	physical	ADJ
admet-512	128	60	meaning	meaning	NOUN
admet-512	128	61	of	of	ADP
admet-512	128	62	the	the	DET
admet-512	128	63	coefficients	coefficient	NOUN
admet-512	128	64	does	do	AUX
admet-512	128	65	not	not	PART
admet-512	128	66	change	change	VERB
admet-512	128	67	.	.	PUNCT
admet-512	129	1	adequate	adequate	ADJ
admet-512	129	2	determination	determination	NOUN
admet-512	129	3	coefficient	coefficient	NOUN
admet-512	129	4	,	,	PUNCT
admet-512	129	5	(	(	PUNCT
admet-512	129	6	a	a	X
admet-512	129	7	)	)	PUNCT
admet-512	129	8	(	(	PUNCT
admet-512	129	9	b	b	X
admet-512	129	10	)	)	PUNCT
admet-512	129	11	marti	marti	PROPN
admet-512	129	12	rosés	rosé	VERB
admet-512	129	13	et	et	PROPN
admet-512	129	14	al	al	PROPN
admet-512	129	15	admet	admet	PROPN
admet-512	129	16	&	&	CCONJ
admet-512	129	17	dmpk	dmpk	PROPN
admet-512	129	18	6(2	6(2	NUM
admet-512	129	19	)	)	PUNCT
admet-512	129	20	(	(	PUNCT
admet-512	129	21	2018	2018	NUM
admet-512	129	22	)	)	PUNCT
admet-512	129	23	140	140	NUM
admet-512	129	24	-	-	SYM
admet-512	129	25	152	152	NUM
admet-512	129	26	148	148	NUM
admet-512	129	27	standard	standard	ADJ
admet-512	129	28	deviation	deviation	NOUN
admet-512	129	29	and	and	CCONJ
admet-512	129	30	f	f	PROPN
admet-512	129	31	values	value	NOUN
admet-512	129	32	were	be	AUX
admet-512	129	33	obtained	obtain	VERB
admet-512	129	34	.	.	PUNCT
admet-512	130	1	q	q	X
admet-512	131	1	2	2	NUM
admet-512	131	2	lmo	lmo	NOUN
admet-512	131	3	was	be	AUX
admet-512	131	4	higher	high	ADJ
admet-512	131	5	than	than	ADP
admet-512	131	6	0.6	0.6	NUM
admet-512	131	7	and	and	CCONJ
admet-512	131	8	it	it	PRON
admet-512	131	9	can	can	AUX
admet-512	131	10	be	be	AUX
admet-512	131	11	ensured	ensure	VERB
admet-512	131	12	that	that	SCONJ
admet-512	131	13	none	none	NOUN
admet-512	131	14	of	of	ADP
admet-512	131	15	the	the	DET
admet-512	131	16	compounds	compound	NOUN
admet-512	131	17	present	present	ADJ
admet-512	131	18	in	in	ADP
admet-512	131	19	the	the	DET
admet-512	131	20	training	training	NOUN
admet-512	131	21	set	set	NOUN
admet-512	131	22	has	have	AUX
admet-512	131	23	had	have	VERB
admet-512	131	24	a	a	DET
admet-512	131	25	big	big	ADJ
admet-512	131	26	influence	influence	NOUN
admet-512	131	27	in	in	ADP
admet-512	131	28	the	the	DET
admet-512	131	29	final	final	ADJ
admet-512	131	30	model	model	NOUN
admet-512	131	31	equation	equation	NOUN
admet-512	131	32	.	.	PUNCT
admet-512	132	1	to	to	PART
admet-512	132	2	perform	perform	VERB
admet-512	132	3	the	the	DET
admet-512	132	4	external	external	ADJ
admet-512	132	5	validation	validation	NOUN
admet-512	132	6	,	,	PUNCT
admet-512	132	7	the	the	DET
admet-512	132	8	log	log	NOUN
admet-512	132	9	kp	kp	PROPN
admet-512	132	10	values	value	NOUN
admet-512	132	11	of	of	ADP
admet-512	132	12	the	the	DET
admet-512	132	13	21	21	NUM
admet-512	132	14	compounds	compound	NOUN
admet-512	132	15	of	of	ADP
admet-512	132	16	the	the	DET
admet-512	132	17	test	test	NOUN
admet-512	132	18	set	set	NOUN
admet-512	132	19	were	be	AUX
admet-512	132	20	predicted	predict	VERB
admet-512	132	21	through	through	ADP
admet-512	132	22	the	the	DET
admet-512	132	23	training	training	NOUN
admet-512	132	24	set	set	NOUN
admet-512	132	25	equation	equation	NOUN
admet-512	132	26	(	(	PUNCT
admet-512	132	27	eq	eq	NOUN
admet-512	132	28	.	.	PROPN
admet-512	132	29	5	5	NUM
admet-512	132	30	)	)	PUNCT
admet-512	132	31	.	.	PUNCT
admet-512	133	1	agreement	agreement	NOUN
admet-512	133	2	between	between	ADP
admet-512	133	3	experimental	experimental	ADJ
admet-512	133	4	and	and	CCONJ
admet-512	133	5	predicted	predict	VERB
admet-512	133	6	kp	kp	PROPN
admet-512	133	7	values	value	NOUN
admet-512	133	8	is	be	AUX
admet-512	133	9	shown	show	VERB
admet-512	133	10	in	in	ADP
admet-512	133	11	figure	figure	NOUN
admet-512	133	12	2b	2b	NOUN
admet-512	133	13	and	and	CCONJ
admet-512	133	14	through	through	ADP
admet-512	133	15	equation	equation	NOUN
admet-512	133	16	6	6	NUM
admet-512	133	17	:	:	PUNCT
admet-512	133	18	log	log	NOUN
admet-512	133	19	kp	kp	NOUN
admet-512	133	20	,	,	PUNCT
admet-512	133	21	pred	pre	VERB
admet-512	133	22	=	=	NOUN
admet-512	133	23	1.08(±0.53	1.08(±0.53	NOUN
admet-512	133	24	)	)	PUNCT
admet-512	134	1	+	+	CCONJ
admet-512	134	2	0.82(±0.09	0.82(±0.09	NOUN
admet-512	134	3	)	)	PUNCT
admet-512	134	4	log	log	NOUN
admet-512	134	5	kp	kp	PROPN
admet-512	134	6	,	,	PUNCT
admet-512	134	7	exp	exp	NOUN
admet-512	134	8	(	(	PUNCT
admet-512	134	9	6	6	NUM
admet-512	134	10	)	)	PUNCT
admet-512	134	11	n	n	NOUN
admet-512	134	12	=	=	SYM
admet-512	134	13	21	21	NUM
admet-512	134	14	r	r	NOUN
admet-512	134	15	2	2	NUM
admet-512	134	16	=	=	SYM
admet-512	134	17	0.807	0.807	NUM
admet-512	134	18	sd	sd	ADP
admet-512	134	19	=	=	SYM
admet-512	134	20	0.469	0.469	NUM
admet-512	134	21	f	f	X
admet-512	134	22	=	=	SYM
admet-512	134	23	80	80	NUM
admet-512	134	24	q	q	NOUN
admet-512	134	25	2	2	NUM
admet-512	134	26	lmo=0.983	lmo=0.983	NOUN
admet-512	134	27	according	accord	VERB
admet-512	134	28	to	to	ADP
admet-512	134	29	statistics	statistic	NOUN
admet-512	134	30	,	,	PUNCT
admet-512	134	31	the	the	DET
admet-512	134	32	model	model	NOUN
admet-512	134	33	shows	show	VERB
admet-512	134	34	good	good	ADJ
admet-512	134	35	prediction	prediction	NOUN
admet-512	134	36	ability	ability	NOUN
admet-512	134	37	:	:	PUNCT
admet-512	134	38	the	the	DET
admet-512	134	39	slope	slope	NOUN
admet-512	134	40	and	and	CCONJ
admet-512	134	41	intercept	intercept	NOUN
admet-512	134	42	of	of	ADP
admet-512	134	43	the	the	DET
admet-512	134	44	trend	trend	NOUN
admet-512	134	45	line	line	NOUN
admet-512	134	46	are	be	AUX
admet-512	134	47	not	not	PART
admet-512	134	48	significantly	significantly	ADV
admet-512	134	49	different	different	ADJ
admet-512	134	50	from	from	ADP
admet-512	134	51	unity	unity	NOUN
admet-512	134	52	and	and	CCONJ
admet-512	134	53	zero	zero	NUM
admet-512	134	54	,	,	PUNCT
admet-512	134	55	respectively	respectively	ADV
admet-512	134	56	,	,	PUNCT
admet-512	134	57	at	at	ADP
admet-512	134	58	95	95	NUM
admet-512	134	59	%	%	NOUN
admet-512	134	60	confidence	confidence	NOUN
admet-512	134	61	level	level	NOUN
admet-512	134	62	according	accord	VERB
admet-512	134	63	to	to	ADP
admet-512	134	64	student	student	NOUN
admet-512	134	65	’s	’s	PROPN
admet-512	134	66	t	t	PROPN
admet-512	134	67	test	test	NOUN
admet-512	134	68	.	.	PUNCT
admet-512	135	1	the	the	DET
admet-512	135	2	determination	determination	NOUN
admet-512	135	3	coefficient	coefficient	NOUN
admet-512	135	4	is	be	AUX
admet-512	135	5	above	above	ADP
admet-512	135	6	0.6	0.6	NUM
admet-512	135	7	,	,	PUNCT
admet-512	135	8	the	the	DET
admet-512	135	9	correlation	correlation	NOUN
admet-512	135	10	cross	cross	ADJ
admet-512	135	11	-	-	ADJ
admet-512	135	12	validation	validation	ADJ
admet-512	135	13	coefficient	coefficient	NOUN
admet-512	135	14	is	be	AUX
admet-512	135	15	above	above	ADP
admet-512	135	16	0.5	0.5	NUM
admet-512	135	17	and	and	CCONJ
admet-512	135	18	fisher	fisher	PROPN
admet-512	135	19	’s	’s	PART
admet-512	135	20	f	f	PROPN
admet-512	135	21	parameter	parameter	NOUN
admet-512	135	22	is	be	AUX
admet-512	135	23	significant	significant	ADJ
admet-512	135	24	.	.	PUNCT
admet-512	136	1	prediction	prediction	NOUN
admet-512	136	2	of	of	ADP
admet-512	136	3	log	log	NOUN
admet-512	136	4	kp	kp	PROPN
admet-512	136	5	values	value	NOUN
admet-512	136	6	as	as	ADP
admet-512	136	7	a	a	DET
admet-512	136	8	first	first	ADJ
admet-512	136	9	step	step	NOUN
admet-512	136	10	,	,	PUNCT
admet-512	136	11	skin	skin	NOUN
admet-512	136	12	permeability	permeability	NOUN
admet-512	136	13	coefficients	coefficient	NOUN
admet-512	136	14	of	of	ADP
admet-512	136	15	the	the	DET
admet-512	136	16	neutral	neutral	ADJ
admet-512	136	17	species	specie	NOUN
admet-512	136	18	of	of	ADP
admet-512	136	19	a	a	DET
admet-512	136	20	set	set	NOUN
admet-512	136	21	of	of	ADP
admet-512	136	22	20	20	NUM
admet-512	136	23	solutes	solute	NOUN
admet-512	136	24	were	be	AUX
admet-512	136	25	determined	determine	VERB
admet-512	136	26	through	through	ADP
admet-512	136	27	the	the	DET
admet-512	136	28	model	model	NOUN
admet-512	136	29	equation	equation	NOUN
admet-512	136	30	(	(	PUNCT
admet-512	136	31	eq	eq	NOUN
admet-512	136	32	.	.	PROPN
admet-512	136	33	4	4	NUM
admet-512	136	34	)	)	PUNCT
admet-512	136	35	,	,	PUNCT
admet-512	136	36	after	after	ADP
admet-512	136	37	measuring	measure	VERB
admet-512	136	38	their	their	PRON
admet-512	136	39	retention	retention	NOUN
admet-512	136	40	factors	factor	NOUN
admet-512	136	41	in	in	ADP
admet-512	136	42	the	the	DET
admet-512	136	43	hplc	hplc	NOUN
admet-512	136	44	system	system	NOUN
admet-512	136	45	.	.	PUNCT
admet-512	137	1	table	table	NOUN
admet-512	137	2	2	2	NUM
admet-512	137	3	shows	show	VERB
admet-512	137	4	the	the	DET
admet-512	137	5	experimental	experimental	ADJ
admet-512	137	6	log	log	NOUN
admet-512	137	7	kp	kp	PROPN
admet-512	137	8	values	value	NOUN
admet-512	137	9	[	[	X
admet-512	137	10	26	26	NUM
admet-512	137	11	,	,	PUNCT
admet-512	137	12	27	27	NUM
admet-512	137	13	]	]	PUNCT
admet-512	137	14	for	for	ADP
admet-512	137	15	these	these	DET
admet-512	137	16	compounds	compound	NOUN
admet-512	137	17	,	,	PUNCT
admet-512	137	18	the	the	DET
admet-512	137	19	values	value	NOUN
admet-512	137	20	predicted	predict	VERB
admet-512	137	21	through	through	ADP
admet-512	137	22	eq	eq	NOUN
admet-512	137	23	.	.	PROPN
admet-512	137	24	4	4	NUM
admet-512	137	25	,	,	PUNCT
admet-512	137	26	and	and	CCONJ
admet-512	137	27	also	also	ADV
admet-512	137	28	the	the	DET
admet-512	137	29	values	value	NOUN
admet-512	137	30	predicted	predict	VERB
admet-512	137	31	by	by	ADP
admet-512	137	32	the	the	DET
admet-512	137	33	solvation	solvation	NOUN
admet-512	137	34	parameter	parameter	NOUN
admet-512	137	35	model	model	NOUN
admet-512	137	36	(	(	PUNCT
admet-512	137	37	eq	eq	NOUN
admet-512	137	38	.	.	PROPN
admet-512	137	39	1	1	NUM
admet-512	137	40	)	)	PUNCT
admet-512	137	41	.	.	PUNCT
admet-512	138	1	for	for	ADP
admet-512	138	2	the	the	DET
admet-512	138	3	latter	latter	ADJ
admet-512	138	4	prediction	prediction	NOUN
admet-512	138	5	the	the	DET
admet-512	138	6	knowledge	knowledge	NOUN
admet-512	138	7	of	of	ADP
admet-512	138	8	solvation	solvation	NOUN
admet-512	138	9	parameter	parameter	NOUN
admet-512	138	10	model	model	NOUN
admet-512	138	11	descriptors	descriptor	NOUN
admet-512	138	12	of	of	ADP
admet-512	138	13	the	the	DET
admet-512	138	14	compounds	compound	NOUN
admet-512	138	15	is	be	AUX
admet-512	138	16	necessary	necessary	ADJ
admet-512	138	17	.	.	PUNCT
admet-512	139	1	there	there	PRON
admet-512	139	2	is	be	VERB
admet-512	139	3	quite	quite	ADV
admet-512	139	4	good	good	ADJ
admet-512	139	5	agreement	agreement	NOUN
admet-512	139	6	between	between	ADP
admet-512	139	7	the	the	DET
admet-512	139	8	experimental	experimental	ADJ
admet-512	139	9	log	log	NOUN
admet-512	139	10	kp	kp	PROPN
admet-512	139	11	values	value	NOUN
admet-512	139	12	and	and	CCONJ
admet-512	139	13	the	the	DET
admet-512	139	14	values	value	NOUN
admet-512	139	15	obtained	obtain	VERB
admet-512	139	16	by	by	ADP
admet-512	139	17	eq	eq	NOUN
admet-512	139	18	.	.	PROPN
admet-512	139	19	4	4	X
admet-512	139	20	.	.	X
admet-512	140	1	in	in	ADP
admet-512	140	2	most	most	ADJ
admet-512	140	3	cases	case	NOUN
admet-512	140	4	the	the	DET
admet-512	140	5	error	error	NOUN
admet-512	140	6	is	be	AUX
admet-512	140	7	around	around	ADV
admet-512	140	8	10	10	NUM
admet-512	140	9	%	%	NOUN
admet-512	140	10	,	,	PUNCT
admet-512	140	11	and	and	CCONJ
admet-512	140	12	is	be	AUX
admet-512	140	13	similar	similar	ADJ
admet-512	140	14	to	to	ADP
admet-512	140	15	the	the	DET
admet-512	140	16	error	error	NOUN
admet-512	140	17	presented	present	VERB
admet-512	140	18	by	by	ADP
admet-512	140	19	the	the	DET
admet-512	140	20	abraham	abraham	PROPN
admet-512	140	21	model	model	NOUN
admet-512	140	22	(	(	PUNCT
admet-512	140	23	eq	eq	NOUN
admet-512	140	24	.	.	PROPN
admet-512	140	25	1	1	NUM
admet-512	140	26	)	)	PUNCT
admet-512	140	27	.	.	PUNCT
admet-512	141	1	figure	figure	NOUN
admet-512	141	2	3	3	NUM
admet-512	141	3	represents	represent	VERB
admet-512	141	4	the	the	DET
admet-512	141	5	experimental	experimental	ADJ
admet-512	141	6	values	value	NOUN
admet-512	141	7	against	against	ADP
admet-512	141	8	the	the	DET
admet-512	141	9	log	log	NOUN
admet-512	141	10	kp	kp	PROPN
admet-512	141	11	obtained	obtain	VERB
admet-512	141	12	by	by	ADP
admet-512	141	13	both	both	DET
admet-512	141	14	models	model	NOUN
admet-512	141	15	.	.	PUNCT
admet-512	142	1	the	the	DET
admet-512	142	2	solid	solid	ADJ
admet-512	142	3	line	line	NOUN
admet-512	142	4	represents	represent	VERB
admet-512	142	5	the	the	DET
admet-512	142	6	theoretical	theoretical	ADJ
admet-512	142	7	line	line	NOUN
admet-512	142	8	of	of	ADP
admet-512	142	9	slope	slope	NOUN
admet-512	142	10	equal	equal	ADJ
admet-512	142	11	to	to	ADP
admet-512	142	12	one	one	NUM
admet-512	142	13	and	and	CCONJ
admet-512	142	14	zero	zero	NUM
admet-512	142	15	intercept	intercept	NOUN
admet-512	142	16	.	.	PUNCT
admet-512	143	1	the	the	DET
admet-512	143	2	plot	plot	NOUN
admet-512	143	3	clearly	clearly	ADV
admet-512	143	4	indicates	indicate	VERB
admet-512	143	5	that	that	SCONJ
admet-512	143	6	the	the	DET
admet-512	143	7	accuracy	accuracy	NOUN
admet-512	143	8	of	of	ADP
admet-512	143	9	both	both	DET
admet-512	143	10	models	model	NOUN
admet-512	143	11	is	be	AUX
admet-512	143	12	very	very	ADV
admet-512	143	13	similar	similar	ADJ
admet-512	143	14	,	,	PUNCT
admet-512	143	15	with	with	ADP
admet-512	143	16	points	point	NOUN
admet-512	143	17	equally	equally	ADV
admet-512	143	18	distributed	distribute	VERB
admet-512	143	19	at	at	ADP
admet-512	143	20	both	both	DET
admet-512	143	21	sides	side	NOUN
admet-512	143	22	of	of	ADP
admet-512	143	23	the	the	DET
admet-512	143	24	theoretical	theoretical	ADJ
admet-512	143	25	line	line	NOUN
admet-512	143	26	,	,	PUNCT
admet-512	143	27	and	and	CCONJ
admet-512	143	28	with	with	ADP
admet-512	143	29	similar	similar	ADJ
admet-512	143	30	dispersion	dispersion	NOUN
admet-512	143	31	.	.	PUNCT
admet-512	144	1	only	only	ADV
admet-512	144	2	famotidine	famotidine	NOUN
admet-512	144	3	presents	present	VERB
admet-512	144	4	an	an	DET
admet-512	144	5	anomalous	anomalous	ADJ
admet-512	144	6	low	low	ADJ
admet-512	144	7	log	log	NOUN
admet-512	144	8	kp	kp	PROPN
admet-512	144	9	value	value	NOUN
admet-512	144	10	when	when	SCONJ
admet-512	144	11	predicted	predict	VERB
admet-512	144	12	by	by	ADP
admet-512	144	13	the	the	DET
admet-512	144	14	abraham	abraham	PROPN
admet-512	144	15	model	model	PROPN
admet-512	144	16	.	.	PUNCT
admet-512	145	1	in	in	ADP
admet-512	145	2	a	a	DET
admet-512	145	3	second	second	ADJ
admet-512	145	4	step	step	NOUN
admet-512	145	5	,	,	PUNCT
admet-512	145	6	log	log	PROPN
admet-512	145	7	kp	kp	PROPN
admet-512	145	8	values	value	NOUN
admet-512	145	9	were	be	AUX
admet-512	145	10	predicted	predict	VERB
admet-512	145	11	again	again	ADV
admet-512	145	12	through	through	ADP
admet-512	145	13	eq	eq	NOUN
admet-512	145	14	.	.	PROPN
admet-512	145	15	4	4	NUM
admet-512	145	16	and	and	CCONJ
admet-512	145	17	then	then	ADV
admet-512	145	18	through	through	ADP
admet-512	145	19	eq	eq	ADP
admet-512	145	20	.	.	PROPN
admet-512	145	21	1	1	NUM
admet-512	145	22	for	for	ADP
admet-512	145	23	another	another	DET
admet-512	145	24	set	set	NOUN
admet-512	145	25	of	of	ADP
admet-512	145	26	9	9	NUM
admet-512	145	27	compounds	compound	NOUN
admet-512	145	28	,	,	PUNCT
admet-512	145	29	for	for	ADP
admet-512	145	30	which	which	PRON
admet-512	145	31	experimental	experimental	ADJ
admet-512	145	32	log	log	NOUN
admet-512	145	33	kp	kp	PROPN
admet-512	145	34	values	value	NOUN
admet-512	145	35	were	be	AUX
admet-512	145	36	not	not	PART
admet-512	145	37	known	know	VERB
admet-512	145	38	.	.	PUNCT
admet-512	146	1	only	only	ADV
admet-512	146	2	for	for	ADP
admet-512	146	3	five	five	NUM
admet-512	146	4	of	of	ADP
admet-512	146	5	them	they	PRON
admet-512	146	6	were	be	AUX
admet-512	146	7	the	the	DET
admet-512	146	8	values	value	NOUN
admet-512	146	9	calculated	calculate	VERB
admet-512	146	10	by	by	ADP
admet-512	146	11	patel	patel	PROPN
admet-512	146	12	et	et	PROPN
admet-512	146	13	al	al	PROPN
admet-512	146	14	.	.	PROPN
admet-512	147	1	(	(	PUNCT
admet-512	147	2	5	5	X
admet-512	147	3	)	)	PUNCT
admet-512	147	4	available	available	ADJ
admet-512	147	5	.	.	PUNCT
admet-512	148	1	as	as	SCONJ
admet-512	148	2	indicated	indicate	VERB
admet-512	148	3	in	in	ADP
admet-512	148	4	table	table	NOUN
admet-512	148	5	3	3	NUM
admet-512	148	6	,	,	PUNCT
admet-512	148	7	comparison	comparison	NOUN
admet-512	148	8	of	of	ADP
admet-512	148	9	the	the	DET
admet-512	148	10	data	datum	NOUN
admet-512	148	11	demonstrates	demonstrate	VERB
admet-512	148	12	that	that	SCONJ
admet-512	148	13	values	value	NOUN
admet-512	148	14	obtained	obtain	VERB
admet-512	148	15	through	through	ADP
admet-512	148	16	chromatographic	chromatographic	ADJ
admet-512	148	17	measurements	measurement	NOUN
admet-512	148	18	(	(	PUNCT
admet-512	148	19	eq	eq	NOUN
admet-512	148	20	.	.	NOUN
admet-512	148	21	4	4	NUM
admet-512	148	22	)	)	PUNCT
admet-512	148	23	and	and	CCONJ
admet-512	148	24	through	through	ADP
admet-512	148	25	the	the	DET
admet-512	148	26	abraham	abraham	PROPN
admet-512	148	27	model	model	NOUN
admet-512	148	28	(	(	PUNCT
admet-512	148	29	eq	eq	NOUN
admet-512	148	30	.	.	NOUN
admet-512	148	31	1	1	NUM
admet-512	148	32	)	)	PUNCT
admet-512	148	33	are	be	AUX
admet-512	148	34	in	in	ADP
admet-512	148	35	general	general	ADJ
admet-512	148	36	consistent	consistent	ADJ
admet-512	148	37	.	.	PUNCT
admet-512	149	1	however	however	ADV
admet-512	149	2	,	,	PUNCT
admet-512	149	3	patel	patel	PROPN
admet-512	149	4	’s	’s	PART
admet-512	149	5	predictions	prediction	NOUN
admet-512	149	6	are	be	AUX
admet-512	149	7	systematically	systematically	ADV
admet-512	149	8	lower	low	ADJ
admet-512	149	9	compared	compare	VERB
admet-512	149	10	to	to	ADP
admet-512	149	11	the	the	DET
admet-512	149	12	other	other	ADJ
admet-512	149	13	two	two	NUM
admet-512	149	14	models	model	NOUN
admet-512	149	15	.	.	PUNCT
admet-512	150	1	finally	finally	ADV
admet-512	150	2	log	log	VERB
admet-512	150	3	kp	kp	PROPN
admet-512	150	4	values	value	NOUN
admet-512	150	5	for	for	ADP
admet-512	150	6	four	four	NUM
admet-512	150	7	compounds	compound	NOUN
admet-512	150	8	of	of	ADP
admet-512	150	9	pharmaceutical	pharmaceutical	ADJ
admet-512	150	10	interest	interest	NOUN
admet-512	150	11	(	(	PUNCT
admet-512	150	12	capsaicin	capsaicin	NOUN
admet-512	150	13	,	,	PUNCT
admet-512	150	14	oxycodone	oxycodone	NOUN
admet-512	150	15	,	,	PUNCT
admet-512	150	16	tramadol	tramadol	NOUN
admet-512	150	17	,	,	PUNCT
admet-512	150	18	and	and	CCONJ
admet-512	150	19	warfarin	warfarin	NOUN
admet-512	150	20	)	)	PUNCT
admet-512	150	21	are	be	AUX
admet-512	150	22	proposed	propose	VERB
admet-512	150	23	for	for	ADP
admet-512	150	24	the	the	DET
admet-512	150	25	first	first	ADJ
admet-512	150	26	time	time	NOUN
admet-512	150	27	.	.	PUNCT
admet-512	151	1	admet	admet	PROPN
admet-512	151	2	&	&	CCONJ
admet-512	151	3	dmpk	dmpk	PROPN
admet-512	151	4	6(2	6(2	NUM
admet-512	151	5	)	)	PUNCT
admet-512	151	6	(	(	PUNCT
admet-512	151	7	2018	2018	NUM
admet-512	151	8	)	)	PUNCT
admet-512	151	9	140	140	NUM
admet-512	151	10	-	-	SYM
admet-512	151	11	152	152	NUM
admet-512	151	12	estimation	estimation	NOUN
admet-512	151	13	of	of	ADP
admet-512	151	14	skin	skin	NOUN
admet-512	151	15	permeation	permeation	NOUN
admet-512	151	16	by	by	ADP
admet-512	151	17	liquid	liquid	ADJ
admet-512	151	18	chromatography	chromatography	NOUN
admet-512	151	19	doi	doi	NOUN
admet-512	151	20	:	:	PUNCT
admet-512	151	21	10.5599	10.5599	NUM
admet-512	151	22	/	/	SYM
admet-512	151	23	admet.512	admet.512	NOUN
admet-512	151	24	149	149	NUM
admet-512	151	25	table	table	NOUN
admet-512	151	26	2	2	NUM
admet-512	151	27	.	.	PUNCT
admet-512	151	28	comparison	comparison	NOUN
admet-512	151	29	of	of	ADP
admet-512	151	30	experimental	experimental	ADJ
admet-512	151	31	(	(	PUNCT
admet-512	151	32	in	in	ADP
admet-512	151	33	vitro	vitro	X
admet-512	151	34	)	)	PUNCT
admet-512	151	35	and	and	CCONJ
admet-512	151	36	predicted	predict	VERB
admet-512	151	37	log	log	PROPN
admet-512	151	38	kp	kp	PROPN
admet-512	151	39	values	value	NOUN
admet-512	151	40	compounds	compound	NOUN
admet-512	151	41	in	in	ADP
admet-512	151	42	vitro	vitro	X
admet-512	151	43	log	log	PROPN
admet-512	151	44	kp	kp	PROPN
admet-512	151	45	values	value	NOUN
admet-512	151	46	predicted	predict	VERB
admet-512	151	47	log	log	PROPN
admet-512	151	48	kp	kp	PROPN
admet-512	151	49	values	value	NOUN
admet-512	152	1	[	[	X
admet-512	152	2	26	26	NUM
admet-512	152	3	]	]	X
admet-512	153	1	[	[	X
admet-512	153	2	27	27	NUM
admet-512	153	3	]	]	PUNCT
admet-512	153	4	this	this	DET
admet-512	153	5	method	method	NOUN
admet-512	153	6	[	[	X
admet-512	153	7	15	15	NUM
admet-512	153	8	]	]	X
admet-512	153	9	aminopyrine	aminopyrine	NOUN
admet-512	153	10	-6.55	-6.55	CCONJ
admet-512	153	11	-6.45	-6.45	X
admet-512	153	12	-6.97	-6.97	NOUN
admet-512	153	13	antipyrine	antipyrine	VERB
admet-512	153	14	-7.74	-7.74	NUM
admet-512	153	15	-6.56	-6.56	NUM
admet-512	153	16	-7.31	-7.31	NOUN
admet-512	153	17	atrazine	atrazine	NOUN
admet-512	153	18	-5.56	-5.56	NOUN
admet-512	153	19	-5.26	-5.26	NUM
admet-512	153	20	-5.45	-5.45	ADJ
admet-512	153	21	catechol	catechol	NOUN
admet-512	153	22	-6.07	-6.07	NUM
admet-512	153	23	-5.88	-5.88	NUM
admet-512	153	24	-5.96	-5.96	NOUN
admet-512	153	25	cortexolone	cortexolone	NOUN
admet-512	153	26	-7.68	-7.68	PUNCT
admet-512	153	27	-6.72	-6.72	NOUN
admet-512	153	28	-5.94	-5.94	NUM
admet-512	153	29	cortisone	cortisone	PROPN
admet-512	153	30	-7.38	-7.38	PROPN
admet-512	153	31	-7.29	-7.29	PROPN
admet-512	153	32	-6.74	-6.74	NOUN
admet-512	153	33	estriol	estriol	PROPN
admet-512	153	34	-7.95	-7.95	NUM
admet-512	153	35	-7.09	-7.09	PROPN
admet-512	153	36	-6.67	-6.67	NOUN
admet-512	153	37	estrone	estrone	NOUN
admet-512	153	38	-6.00	-6.00	X
admet-512	153	39	-5.29	-5.29	PROPN
admet-512	153	40	-5.11	-5.11	CCONJ
admet-512	153	41	famotidine	famotidine	PROPN
admet-512	153	42	-8.35	-8.35	PROPN
admet-512	153	43	-7.63	-7.63	PROPN
admet-512	153	44	-10.49	-10.49	PROPN
admet-512	153	45	flurbiprofen	flurbiprofen	NOUN
admet-512	153	46	-3.40	-3.40	PROPN
admet-512	153	47	-4.60	-4.60	PROPN
admet-512	153	48	-4.09	-4.09	PROPN
admet-512	153	49	griseofulvin	griseofulvin	PROPN
admet-512	153	50	-6.44	-6.44	ADP
admet-512	153	51	-5.93	-5.93	NUM
admet-512	153	52	-5.92	-5.92	NUM
admet-512	153	53	hydroquinone	hydroquinone	PROPN
admet-512	153	54	-6.51	-6.51	PROPN
admet-512	153	55	-6.32	-6.32	PUNCT
admet-512	153	56	-6.44	-6.44	PUNCT
admet-512	153	57	hydroxyprogesterone	hydroxyprogesterone	PROPN
admet-512	153	58	-6.78	-6.78	PROPN
admet-512	153	59	-5.80	-5.80	NOUN
admet-512	153	60	-5.08	-5.08	PROPN
admet-512	153	61	ketoprofen	ketoprofen	NOUN
admet-512	153	62	-4.71	-4.71	X
admet-512	153	63	-5.43	-5.43	NUM
admet-512	153	64	-5.06	-5.06	PRON
admet-512	153	65	ketorolac	ketorolac	PROPN
admet-512	153	66	-5.80	-5.80	NOUN
admet-512	153	67	-5.79	-5.79	NUM
admet-512	153	68	-5.72	-5.72	NOUN
admet-512	153	69	piroxicam	piroxicam	PROPN
admet-512	153	70	-6.02	-6.02	CCONJ
admet-512	153	71	-6.19	-6.19	NUM
admet-512	153	72	-7.18	-7.18	PUNCT
admet-512	153	73	prednisolone	prednisolone	PROPN
admet-512	153	74	-7.91	-7.91	PROPN
admet-512	153	75	-7.46	-7.46	PROPN
admet-512	153	76	-6.90	-6.90	PROPN
admet-512	153	77	pregnenolone	pregnenolone	NOUN
admet-512	153	78	-6.38	-6.38	NOUN
admet-512	153	79	-4.93	-4.93	NUM
admet-512	153	80	-4.70	-4.70	NUM
admet-512	153	81	propanolol	propanolol	NOUN
admet-512	153	82	-6.05	-6.05	NOUN
admet-512	153	83	-4.96	-4.96	X
admet-512	153	84	-5.71	-5.71	PUNCT
admet-512	153	85	ranitidine	ranitidine	NOUN
admet-512	153	86	-7.61	-7.61	PUNCT
admet-512	153	87	-7.17	-7.17	PROPN
admet-512	153	88	-7.97	-7.97	NOUN
admet-512	153	89	figure	figure	NOUN
admet-512	153	90	3	3	NUM
admet-512	153	91	.	.	PUNCT
admet-512	153	92	experimental	experimental	PROPN
admet-512	153	93	vs.	vs.	SCONJ
admet-512	153	94	predicted	predict	VERB
admet-512	153	95	log	log	PROPN
admet-512	153	96	kp	kp	PROPN
admet-512	153	97	values	value	NOUN
admet-512	153	98	.	.	PUNCT
admet-512	154	1	for	for	ADP
admet-512	154	2	each	each	DET
admet-512	154	3	compound	compound	NOUN
admet-512	154	4	,	,	PUNCT
admet-512	154	5	log	log	PROPN
admet-512	154	6	kp	kp	PROPN
admet-512	154	7	is	be	AUX
admet-512	154	8	predicted	predict	VERB
admet-512	154	9	through	through	ADP
admet-512	154	10	the	the	DET
admet-512	154	11	chromatographic	chromatographic	ADJ
admet-512	154	12	model	model	NOUN
admet-512	154	13	(	(	PUNCT
admet-512	154	14	●	●	NOUN
admet-512	154	15	)	)	PUNCT
admet-512	154	16	and	and	CCONJ
admet-512	154	17	through	through	ADP
admet-512	154	18	the	the	DET
admet-512	154	19	solvation	solvation	NOUN
admet-512	154	20	parameter	parameter	NOUN
admet-512	154	21	model	model	NOUN
admet-512	154	22	(	(	PUNCT
admet-512	154	23	▲	▲	PUNCT
admet-512	154	24	)	)	PUNCT
admet-512	154	25	marti	marti	PROPN
admet-512	154	26	rosés	rosé	VERB
admet-512	154	27	et	et	PROPN
admet-512	154	28	al	al	PROPN
admet-512	154	29	admet	admet	PROPN
admet-512	154	30	&	&	CCONJ
admet-512	154	31	dmpk	dmpk	PROPN
admet-512	154	32	6(2	6(2	NUM
admet-512	154	33	)	)	PUNCT
admet-512	154	34	(	(	PUNCT
admet-512	154	35	2018	2018	NUM
admet-512	154	36	)	)	PUNCT
admet-512	154	37	140	140	NUM
admet-512	154	38	-	-	SYM
admet-512	154	39	152	152	NUM
admet-512	154	40	150	150	NUM
admet-512	154	41	table	table	NOUN
admet-512	154	42	3	3	NUM
admet-512	154	43	.	.	PUNCT
admet-512	154	44	prediction	prediction	NOUN
admet-512	154	45	of	of	ADP
admet-512	154	46	log	log	NOUN
admet-512	154	47	kp	kp	PROPN
admet-512	154	48	values	value	NOUN
admet-512	154	49	through	through	ADP
admet-512	154	50	different	different	ADJ
admet-512	154	51	estimation	estimation	NOUN
admet-512	154	52	models	model	NOUN
admet-512	154	53	compounds	compound	VERB
admet-512	154	54	this	this	DET
admet-512	154	55	method	method	NOUN
admet-512	154	56	[	[	X
admet-512	154	57	15	15	NUM
admet-512	154	58	]	]	X
admet-512	155	1	[	[	X
admet-512	155	2	5	5	NUM
admet-512	155	3	]	]	SYM
admet-512	155	4	2	2	NUM
admet-512	155	5	-	-	PUNCT
admet-512	155	6	toluidine	toluidine	NOUN
admet-512	155	7	-5.09	-5.09	NUM
admet-512	155	8	-5.22	-5.22	NUM
admet-512	155	9	-5.83	-5.83	ADJ
admet-512	155	10	3	3	NUM
admet-512	155	11	-	-	PUNCT
admet-512	155	12	xylene	xylene	NOUN
admet-512	155	13	-3.37	-3.37	NOUN
admet-512	155	14	-3.93	-3.93	NUM
admet-512	155	15	-4.41	-4.41	NOUN
admet-512	155	16	cumene	cumene	PROPN
admet-512	155	17	-3.11	-3.11	PROPN
admet-512	155	18	-3.59	-3.59	PROPN
admet-512	155	19	-6.14	-6.14	PROPN
admet-512	155	20	n.n	n.n	PROPN
admet-512	155	21	-	-	PUNCT
admet-512	155	22	dimethylaniline	dimethylaniline	NOUN
admet-512	155	23	-4.20	-4.20	NUM
admet-512	155	24	-4.62	-4.62	X
admet-512	155	25	-5.29	-5.29	NUM
admet-512	155	26	pyridine	pyridine	NOUN
admet-512	155	27	-5.56	-5.56	X
admet-512	155	28	-5.90	-5.90	PROPN
admet-512	155	29	-6.10	-6.10	NOUN
admet-512	155	30	capsaicin	capsaicin	NOUN
admet-512	155	31	-5.41	-5.41	CCONJ
admet-512	155	32	-4.19	-4.19	NOUN
admet-512	155	33	oxycodone	oxycodone	NOUN
admet-512	155	34	-5.89	-5.89	NOUN
admet-512	155	35	-7.05	-7.05	NOUN
admet-512	155	36	tramadol	tramadol	NOUN
admet-512	155	37	-5.16	-5.16	PROPN
admet-512	155	38	-5.02	-5.02	NUM
admet-512	155	39	warfarin	warfarin	NOUN
admet-512	155	40	-5.37	-5.37	PROPN
admet-512	155	41	-5.25	-5.25	PROPN
admet-512	155	42	conclusions	conclusion	NOUN
admet-512	155	43	a	a	DET
admet-512	155	44	methodology	methodology	NOUN
admet-512	155	45	has	have	AUX
admet-512	155	46	been	be	AUX
admet-512	155	47	developed	develop	VERB
admet-512	155	48	for	for	ADP
admet-512	155	49	the	the	DET
admet-512	155	50	prediction	prediction	NOUN
admet-512	155	51	of	of	ADP
admet-512	155	52	skin	skin	NOUN
admet-512	155	53	permeability	permeability	NOUN
admet-512	155	54	of	of	ADP
admet-512	155	55	neutral	neutral	ADJ
admet-512	155	56	species	specie	NOUN
admet-512	155	57	.	.	PUNCT
admet-512	156	1	the	the	DET
admet-512	156	2	method	method	NOUN
admet-512	156	3	is	be	AUX
admet-512	156	4	based	base	VERB
admet-512	156	5	on	on	ADP
admet-512	156	6	measurements	measurement	NOUN
admet-512	156	7	on	on	ADP
admet-512	156	8	an	an	DET
admet-512	156	9	hplc	hplc	NOUN
admet-512	156	10	system	system	NOUN
admet-512	156	11	fitted	fit	VERB
admet-512	156	12	with	with	ADP
admet-512	156	13	a	a	DET
admet-512	156	14	c18	c18	NOUN
admet-512	156	15	column	column	NOUN
admet-512	156	16	,	,	PUNCT
admet-512	156	17	coupled	couple	VERB
admet-512	156	18	to	to	ADP
admet-512	156	19	uv	uv	VERB
admet-512	156	20	-	-	PUNCT
admet-512	156	21	vis	vis	X
admet-512	156	22	and	and	CCONJ
admet-512	156	23	ms	ms	NOUN
admet-512	156	24	detection	detection	NOUN
admet-512	156	25	.	.	PUNCT
admet-512	157	1	the	the	DET
admet-512	157	2	model	model	NOUN
admet-512	157	3	has	have	AUX
admet-512	157	4	been	be	AUX
admet-512	157	5	established	establish	VERB
admet-512	157	6	with	with	ADP
admet-512	157	7	a	a	DET
admet-512	157	8	set	set	NOUN
admet-512	157	9	of	of	ADP
admet-512	157	10	63	63	NUM
admet-512	157	11	compounds	compound	NOUN
admet-512	157	12	with	with	ADP
admet-512	157	13	different	different	ADJ
admet-512	157	14	chemical	chemical	ADJ
admet-512	157	15	natures	nature	NOUN
admet-512	157	16	and	and	CCONJ
admet-512	157	17	structural	structural	ADJ
admet-512	157	18	complexity	complexity	NOUN
admet-512	157	19	,	,	PUNCT
admet-512	157	20	which	which	PRON
admet-512	157	21	ensures	ensure	VERB
admet-512	157	22	the	the	DET
admet-512	157	23	applicability	applicability	NOUN
admet-512	157	24	of	of	ADP
admet-512	157	25	the	the	DET
admet-512	157	26	model	model	NOUN
admet-512	157	27	to	to	ADP
admet-512	157	28	a	a	DET
admet-512	157	29	wide	wide	ADJ
admet-512	157	30	range	range	NOUN
admet-512	157	31	of	of	ADP
admet-512	157	32	compounds	compound	NOUN
admet-512	157	33	.	.	PUNCT
admet-512	158	1	the	the	DET
admet-512	158	2	chromatographic	chromatographic	ADJ
admet-512	158	3	retention	retention	NOUN
admet-512	158	4	factor	factor	NOUN
admet-512	158	5	is	be	AUX
admet-512	158	6	the	the	DET
admet-512	158	7	parameter	parameter	NOUN
admet-512	158	8	that	that	PRON
admet-512	158	9	makes	make	VERB
admet-512	158	10	the	the	DET
admet-512	158	11	highest	high	ADJ
admet-512	158	12	contribution	contribution	NOUN
admet-512	158	13	to	to	ADP
admet-512	158	14	the	the	DET
admet-512	158	15	calculation	calculation	NOUN
admet-512	158	16	of	of	ADP
admet-512	158	17	the	the	DET
admet-512	158	18	permeation	permeation	NOUN
admet-512	158	19	through	through	ADP
admet-512	158	20	skin	skin	NOUN
admet-512	158	21	,	,	PUNCT
admet-512	158	22	the	the	DET
admet-512	158	23	kp	kp	PROPN
admet-512	158	24	value	value	NOUN
admet-512	158	25	being	be	AUX
admet-512	158	26	greater	great	ADJ
admet-512	158	27	as	as	ADP
admet-512	158	28	the	the	DET
admet-512	158	29	retention	retention	NOUN
admet-512	158	30	increases	increase	NOUN
admet-512	158	31	.	.	PUNCT
admet-512	159	1	on	on	ADP
admet-512	159	2	the	the	DET
admet-512	159	3	contrary	contrary	NOUN
admet-512	159	4	,	,	PUNCT
admet-512	159	5	the	the	DET
admet-512	159	6	mcgowan	mcgowan	PROPN
admet-512	159	7	volume	volume	NOUN
admet-512	159	8	decreases	decrease	VERB
admet-512	159	9	the	the	DET
admet-512	159	10	permeation	permeation	NOUN
admet-512	159	11	value	value	NOUN
admet-512	159	12	.	.	PUNCT
admet-512	160	1	the	the	DET
admet-512	160	2	model	model	NOUN
admet-512	160	3	has	have	AUX
admet-512	160	4	been	be	AUX
admet-512	160	5	validated	validate	VERB
admet-512	160	6	,	,	PUNCT
admet-512	160	7	showing	show	VERB
admet-512	160	8	both	both	CCONJ
admet-512	160	9	good	good	ADJ
admet-512	160	10	robustness	robustness	NOUN
admet-512	160	11	and	and	CCONJ
admet-512	160	12	good	good	ADJ
admet-512	160	13	prediction	prediction	NOUN
admet-512	160	14	ability	ability	NOUN
admet-512	160	15	.	.	PUNCT
admet-512	161	1	the	the	DET
admet-512	161	2	prediction	prediction	NOUN
admet-512	161	3	ability	ability	NOUN
admet-512	161	4	has	have	AUX
admet-512	161	5	been	be	AUX
admet-512	161	6	further	far	ADV
admet-512	161	7	tested	test	VERB
admet-512	161	8	by	by	ADP
admet-512	161	9	comparison	comparison	NOUN
admet-512	161	10	of	of	ADP
admet-512	161	11	the	the	DET
admet-512	161	12	results	result	NOUN
admet-512	161	13	to	to	ADP
admet-512	161	14	other	other	ADJ
admet-512	161	15	prediction	prediction	NOUN
admet-512	161	16	models	model	NOUN
admet-512	161	17	(	(	PUNCT
admet-512	161	18	abraham	abraham	PROPN
admet-512	161	19	and	and	CCONJ
admet-512	161	20	patel	patel	PROPN
admet-512	161	21	)	)	PUNCT
admet-512	161	22	.	.	PUNCT
admet-512	162	1	results	result	NOUN
admet-512	162	2	from	from	ADP
admet-512	162	3	this	this	DET
admet-512	162	4	work	work	NOUN
admet-512	162	5	are	be	AUX
admet-512	162	6	similar	similar	ADJ
admet-512	162	7	(	(	PUNCT
admet-512	162	8	both	both	CCONJ
admet-512	162	9	in	in	ADP
admet-512	162	10	accuracy	accuracy	NOUN
admet-512	162	11	and	and	CCONJ
admet-512	162	12	precision	precision	NOUN
admet-512	162	13	)	)	PUNCT
admet-512	162	14	to	to	ADP
admet-512	162	15	the	the	DET
admet-512	162	16	results	result	NOUN
admet-512	162	17	obtained	obtain	VERB
admet-512	162	18	through	through	ADP
admet-512	162	19	abraham	abraham	PROPN
admet-512	162	20	’s	’s	PART
admet-512	162	21	model	model	NOUN
admet-512	162	22	.	.	PUNCT
admet-512	163	1	however	however	ADV
admet-512	163	2	,	,	PUNCT
admet-512	163	3	the	the	DET
admet-512	163	4	permeation	permeation	NOUN
admet-512	163	5	coefficients	coefficient	NOUN
admet-512	163	6	obtained	obtain	VERB
admet-512	163	7	through	through	ADP
admet-512	163	8	patel	patel	PROPN
admet-512	163	9	’s	’s	PART
admet-512	163	10	model	model	NOUN
admet-512	163	11	seem	seem	VERB
admet-512	163	12	to	to	PART
admet-512	163	13	be	be	AUX
admet-512	163	14	slightly	slightly	ADV
admet-512	163	15	lower	low	ADJ
admet-512	163	16	.	.	PUNCT
admet-512	164	1	the	the	DET
admet-512	164	2	main	main	ADJ
admet-512	164	3	advantage	advantage	NOUN
admet-512	164	4	of	of	ADP
admet-512	164	5	the	the	DET
admet-512	164	6	present	present	ADJ
admet-512	164	7	methodology	methodology	NOUN
admet-512	164	8	is	be	AUX
admet-512	164	9	that	that	SCONJ
admet-512	164	10	kp	kp	PROPN
admet-512	164	11	can	can	AUX
admet-512	164	12	be	be	AUX
admet-512	164	13	directly	directly	ADV
admet-512	164	14	obtained	obtain	VERB
admet-512	164	15	from	from	ADP
admet-512	164	16	simple	simple	ADJ
admet-512	164	17	chromatographic	chromatographic	ADJ
admet-512	164	18	retention	retention	NOUN
admet-512	164	19	measurements	measurement	NOUN
admet-512	164	20	and	and	CCONJ
admet-512	164	21	the	the	DET
admet-512	164	22	mcgowan	mcgowan	PROPN
admet-512	164	23	’s	’s	PART
admet-512	164	24	molecular	molecular	ADJ
admet-512	164	25	volume	volume	NOUN
admet-512	164	26	of	of	ADP
admet-512	164	27	the	the	DET
admet-512	164	28	compounds	compound	NOUN
admet-512	164	29	,	,	PUNCT
admet-512	164	30	without	without	ADP
admet-512	164	31	the	the	DET
admet-512	164	32	need	need	NOUN
admet-512	164	33	of	of	ADP
admet-512	164	34	additional	additional	ADJ
admet-512	164	35	molecular	molecular	ADJ
admet-512	164	36	descriptors	descriptor	NOUN
admet-512	164	37	calculation	calculation	NOUN
admet-512	164	38	and/or	and/or	CCONJ
admet-512	164	39	determination	determination	NOUN
admet-512	164	40	.	.	PUNCT
admet-512	165	1	acknowledgements	acknowledgement	NOUN
admet-512	165	2	:	:	PUNCT
admet-512	166	1	we	we	PRON
admet-512	166	2	thank	thank	VERB
admet-512	166	3	magda	magda	PROPN
admet-512	166	4	bordas	bordas	PROPN
admet-512	166	5	for	for	ADP
admet-512	166	6	her	her	PRON
admet-512	166	7	expert	expert	NOUN
admet-512	166	8	contribution	contribution	NOUN
admet-512	166	9	to	to	ADP
admet-512	166	10	the	the	DET
admet-512	166	11	analytical	analytical	ADJ
admet-512	166	12	studies	study	NOUN
admet-512	166	13	and	and	CCONJ
admet-512	166	14	with	with	ADP
admet-512	166	15	edmundo	edmundo	PROPN
admet-512	166	16	ortega	ortega	PROPN
admet-512	166	17	for	for	ADP
admet-512	166	18	their	their	PRON
admet-512	166	19	excellent	excellent	ADJ
admet-512	166	20	technical	technical	ADJ
admet-512	166	21	assistance	assistance	NOUN
admet-512	166	22	.	.	PUNCT
admet-512	167	1	we	we	PRON
admet-512	167	2	also	also	ADV
admet-512	167	3	thank	thank	VERB
admet-512	167	4	carmen	carman	NOUN
admet-512	167	5	almansa	almansa	VERB
admet-512	167	6	for	for	ADP
admet-512	167	7	her	her	PRON
admet-512	167	8	very	very	ADV
admet-512	167	9	helpful	helpful	ADJ
admet-512	167	10	discussion	discussion	NOUN
admet-512	167	11	and	and	CCONJ
admet-512	167	12	comments	comment	NOUN
admet-512	167	13	.	.	PUNCT
admet-512	168	1	financial	financial	ADJ
admet-512	168	2	support	support	NOUN
admet-512	168	3	from	from	ADP
admet-512	168	4	the	the	DET
admet-512	168	5	generalitat	generalitat	PROPN
admet-512	168	6	de	de	PROPN
admet-512	168	7	catalunya	catalunya	PROPN
admet-512	168	8	(	(	PUNCT
admet-512	168	9	project	project	NOUN
admet-512	168	10	di-2014	di-2014	PROPN
admet-512	168	11	modality	modality	NOUN
admet-512	168	12	di	di	NOUN
admet-512	168	13	-	-	NOUN
admet-512	168	14	esp	esp	ADJ
admet-512	168	15	,	,	PUNCT
admet-512	168	16	resolution	resolution	NOUN
admet-512	168	17	eco/1426/2014	eco/1426/2014	NOUN
admet-512	168	18	)	)	PUNCT
admet-512	168	19	and	and	CCONJ
admet-512	168	20	the	the	DET
admet-512	168	21	ministerio	ministerio	PROPN
admet-512	168	22	de	de	PROPN
admet-512	168	23	economia	economia	PROPN
admet-512	168	24	y	y	PROPN
admet-512	168	25	competitividad	competitividad	PROPN
admet-512	168	26	from	from	ADP
admet-512	168	27	the	the	DET
admet-512	168	28	spanish	spanish	ADJ
admet-512	168	29	government	government	NOUN
admet-512	168	30	(	(	PUNCT
admet-512	168	31	ctq2014	ctq2014	NOUN
admet-512	168	32	-	-	PUNCT
admet-512	168	33	56253	56253	NUM
admet-512	168	34	-	-	PUNCT
admet-512	168	35	p	p	NOUN
admet-512	168	36	)	)	PUNCT
admet-512	168	37	is	be	AUX
admet-512	168	38	acknowledged	acknowledge	VERB
admet-512	168	39	.	.	PUNCT
admet-512	169	1	references	reference	NOUN
admet-512	169	2	[	[	X
admet-512	169	3	1	1	NUM
admet-512	169	4	]	]	X
admet-512	169	5	h.a.e	h.a.e	NOUN
admet-512	169	6	.	.	PUNCT
admet-512	170	1	benson	benson	PROPN
admet-512	170	2	,	,	PUNCT
admet-512	170	3	a.c	a.c	PROPN
admet-512	170	4	.	.	PROPN
admet-512	170	5	watkinson	watkinson	PROPN
admet-512	170	6	.	.	PUNCT
admet-512	171	1	topical	topical	ADJ
admet-512	171	2	and	and	CCONJ
admet-512	171	3	transdermal	transdermal	ADJ
admet-512	171	4	drug	drug	NOUN
admet-512	171	5	delivery	delivery	NOUN
admet-512	171	6	:	:	PUNCT
admet-512	171	7	principles	principle	NOUN
admet-512	171	8	and	and	CCONJ
admet-512	171	9	practice	practice	NOUN
admet-512	171	10	.	.	PUNCT
admet-512	172	1	wiley	wiley	PROPN
admet-512	172	2	(	(	PUNCT
admet-512	172	3	2012	2012	NUM
admet-512	172	4	)	)	PUNCT
admet-512	172	5	.	.	PUNCT
admet-512	173	1	[	[	X
admet-512	173	2	2	2	NUM
admet-512	173	3	]	]	PUNCT
admet-512	173	4	k.	k.	PROPN
admet-512	173	5	hoang	hoang	PROPN
admet-512	173	6	.	.	PUNCT
admet-512	174	1	dermal	dermal	ADJ
admet-512	174	2	exposure	exposure	NOUN
admet-512	174	3	assessment	assessment	NOUN
admet-512	174	4	:	:	PUNCT
admet-512	174	5	principles	principle	NOUN
admet-512	174	6	and	and	CCONJ
admet-512	174	7	applications	application	NOUN
admet-512	174	8	.	.	PUNCT
admet-512	175	1	washington	washington	PROPN
admet-512	175	2	:	:	PUNCT
admet-512	175	3	environmental	environmental	PROPN
admet-512	175	4	protection	protection	PROPN
admet-512	175	5	agency	agency	PROPN
admet-512	175	6	,	,	PUNCT
admet-512	175	7	office	office	NOUN
admet-512	175	8	of	of	ADP
admet-512	175	9	health	health	NOUN
admet-512	175	10	and	and	CCONJ
admet-512	175	11	environmental	environmental	ADJ
admet-512	175	12	assessment	assessment	NOUN
admet-512	175	13	(	(	PUNCT
admet-512	175	14	1992	1992	NUM
admet-512	175	15	)	)	PUNCT
admet-512	175	16	.	.	PUNCT
admet-512	176	1	[	[	X
admet-512	176	2	3	3	X
admet-512	176	3	]	]	X
admet-512	176	4	j.	j.	PROPN
admet-512	176	5	kielhorn	kielhorn	PROPN
admet-512	176	6	,	,	PUNCT
admet-512	176	7	s.	s.	PROPN
admet-512	176	8	melching	melching	PROPN
admet-512	176	9	-	-	PUNCT
admet-512	176	10	kollmuss	kollmuss	PROPN
admet-512	176	11	,	,	PUNCT
admet-512	176	12	i.	i.	PROPN
admet-512	176	13	mangelsdorf	mangelsdorf	PROPN
admet-512	176	14	.	.	PUNCT
admet-512	177	1	environmental	environmental	ADJ
admet-512	177	2	health	health	NOUN
admet-512	177	3	criteria	criterion	NOUN
admet-512	177	4	235	235	NUM
admet-512	177	5	:	:	PUNCT
admet-512	177	6	dermal	dermal	NOUN
admet-512	177	7	absorption	absorption	NOUN
admet-512	177	8	.	.	PUNCT
admet-512	178	1	geneva	geneva	PROPN
admet-512	178	2	:	:	PUNCT
admet-512	178	3	world	world	PROPN
admet-512	178	4	healt	healt	PROPN
admet-512	178	5	organization	organization	PROPN
admet-512	178	6	press	press	PROPN
admet-512	178	7	(	(	PUNCT
admet-512	178	8	2006	2006	NUM
admet-512	178	9	)	)	PUNCT
admet-512	178	10	.	.	PUNCT
admet-512	179	1	[	[	X
admet-512	179	2	4	4	X
admet-512	179	3	]	]	X
admet-512	179	4	s.	s.	PROPN
admet-512	179	5	geinoz	geinoz	PROPN
admet-512	179	6	,	,	PUNCT
admet-512	179	7	r.h	r.h	PROPN
admet-512	179	8	.	.	PROPN
admet-512	179	9	guy	guy	PROPN
admet-512	179	10	,	,	PUNCT
admet-512	179	11	b.	b.	PROPN
admet-512	179	12	testa	testa	PROPN
admet-512	179	13	,	,	PUNCT
admet-512	179	14	p.	p.	NOUN
admet-512	179	15	carrupt	carrupt	PROPN
admet-512	179	16	.	.	PUNCT
admet-512	180	1	quantitative	quantitative	ADJ
admet-512	180	2	structure	structure	NOUN
admet-512	180	3	-	-	PUNCT
admet-512	180	4	permeation	permeation	NOUN
admet-512	180	5	relationships	relationship	NOUN
admet-512	180	6	(	(	PUNCT
admet-512	180	7	qspers	qsper	NOUN
admet-512	180	8	)	)	PUNCT
admet-512	180	9	to	to	PART
admet-512	180	10	predict	predict	VERB
admet-512	180	11	skin	skin	NOUN
admet-512	180	12	permeation	permeation	NOUN
admet-512	180	13	:	:	PUNCT
admet-512	180	14	a	a	DET
admet-512	180	15	critical	critical	ADJ
admet-512	180	16	evaluation	evaluation	NOUN
admet-512	180	17	.	.	PUNCT
admet-512	181	1	pharmaceutical	pharmaceutical	ADJ
admet-512	181	2	research	research	NOUN
admet-512	181	3	21	21	NUM
admet-512	181	4	(	(	PUNCT
admet-512	181	5	2004	2004	NUM
admet-512	181	6	)	)	PUNCT
admet-512	181	7	83	83	NUM
admet-512	181	8	-	-	SYM
admet-512	181	9	92	92	NUM
admet-512	181	10	.	.	PUNCT
admet-512	182	1	admet	admet	PROPN
admet-512	182	2	&	&	CCONJ
admet-512	182	3	dmpk	dmpk	PROPN
admet-512	182	4	6(2	6(2	NUM
admet-512	182	5	)	)	PUNCT
admet-512	182	6	(	(	PUNCT
admet-512	182	7	2018	2018	NUM
admet-512	182	8	)	)	PUNCT
admet-512	182	9	140	140	NUM
admet-512	182	10	-	-	SYM
admet-512	182	11	152	152	NUM
admet-512	182	12	estimation	estimation	NOUN
admet-512	182	13	of	of	ADP
admet-512	182	14	skin	skin	NOUN
admet-512	182	15	permeation	permeation	NOUN
admet-512	182	16	by	by	ADP
admet-512	182	17	liquid	liquid	ADJ
admet-512	182	18	chromatography	chromatography	NOUN
admet-512	182	19	doi	doi	NOUN
admet-512	182	20	:	:	PUNCT
admet-512	182	21	10.5599	10.5599	NUM
admet-512	182	22	/	/	SYM
admet-512	182	23	admet.512	admet.512	NOUN
admet-512	182	24	151	151	NUM
admet-512	182	25	[	[	SYM
admet-512	182	26	5	5	NUM
admet-512	182	27	]	]	PUNCT
admet-512	182	28	h.	h.	PROPN
admet-512	182	29	patel	patel	PROPN
admet-512	182	30	,	,	PUNCT
admet-512	182	31	w.	w.	PROPN
admet-512	182	32	ten	ten	NUM
admet-512	182	33	berge	berge	NOUN
admet-512	182	34	,	,	PUNCT
admet-512	182	35	m.t.d	m.t.d	PROPN
admet-512	182	36	.	.	PUNCT
admet-512	182	37	cronin	cronin	PROPN
admet-512	182	38	.	.	PUNCT
admet-512	183	1	quantitative	quantitative	ADJ
admet-512	183	2	structure	structure	NOUN
admet-512	183	3	-	-	PUNCT
admet-512	183	4	activity	activity	NOUN
admet-512	183	5	relationships	relationship	NOUN
admet-512	183	6	(	(	PUNCT
admet-512	183	7	qsars	qsar	NOUN
admet-512	183	8	)	)	PUNCT
admet-512	183	9	for	for	ADP
admet-512	183	10	the	the	DET
admet-512	183	11	prediction	prediction	NOUN
admet-512	183	12	of	of	ADP
admet-512	183	13	skin	skin	NOUN
admet-512	183	14	permeation	permeation	NOUN
admet-512	183	15	of	of	ADP
admet-512	183	16	exogenous	exogenous	ADJ
admet-512	183	17	chemicals	chemical	NOUN
admet-512	183	18	.	.	PUNCT
admet-512	184	1	chemosphere	chemosphere	PROPN
admet-512	184	2	48(6	48(6	NOUN
admet-512	184	3	)	)	PUNCT
admet-512	184	4	(	(	PUNCT
admet-512	184	5	2002	2002	NUM
admet-512	184	6	)	)	PUNCT
admet-512	185	1	603–613	603–613	NUM
admet-512	185	2	.	.	PUNCT
admet-512	186	1	[	[	X
admet-512	186	2	6	6	NUM
admet-512	186	3	]	]	PUNCT
admet-512	186	4	s.	s.	PROPN
admet-512	186	5	mitragotri	mitragotri	PROPN
admet-512	186	6	,	,	PUNCT
admet-512	186	7	y.g	y.g	PROPN
admet-512	186	8	.	.	PROPN
admet-512	186	9	anissimov	anissimov	PROPN
admet-512	186	10	,	,	PUNCT
admet-512	186	11	a.l	a.l	PROPN
admet-512	186	12	.	.	PROPN
admet-512	186	13	bunge	bunge	PROPN
admet-512	186	14	,	,	PUNCT
admet-512	186	15	h.f	h.f	PROPN
admet-512	186	16	.	.	PROPN
admet-512	186	17	frasch	frasch	PROPN
admet-512	186	18	,	,	PUNCT
admet-512	186	19	r.h	r.h	PROPN
admet-512	186	20	.	.	PROPN
admet-512	186	21	guy	guy	NOUN
admet-512	186	22	,	,	PUNCT
admet-512	186	23	j.	j.	PROPN
admet-512	186	24	hadgraft	hadgraft	PROPN
admet-512	186	25	,	,	PUNCT
admet-512	186	26	g.b	g.b	PROPN
admet-512	186	27	.	.	PROPN
admet-512	186	28	kasting	kasting	PROPN
admet-512	186	29	,	,	PUNCT
admet-512	186	30	m.e	m.e	PROPN
admet-512	186	31	.	.	PROPN
admet-512	186	32	lane	lane	PROPN
admet-512	186	33	,	,	PUNCT
admet-512	186	34	m.s	m.s	PROPN
admet-512	186	35	.	.	PROPN
admet-512	186	36	roberts	roberts	PROPN
admet-512	186	37	.	.	PROPN
admet-512	186	38	mathematical	mathematical	ADJ
admet-512	186	39	models	model	NOUN
admet-512	186	40	of	of	ADP
admet-512	186	41	skin	skin	NOUN
admet-512	186	42	permeability	permeability	NOUN
admet-512	186	43	:	:	PUNCT
admet-512	186	44	an	an	DET
admet-512	186	45	overview	overview	NOUN
admet-512	186	46	.	.	PUNCT
admet-512	187	1	international	international	ADJ
admet-512	187	2	journal	journal	PROPN
admet-512	187	3	of	of	ADP
admet-512	187	4	pharmaceutics	pharmaceutic	NOUN
admet-512	187	5	418	418	NUM
admet-512	187	6	(	(	PUNCT
admet-512	187	7	2011	2011	NUM
admet-512	187	8	)	)	PUNCT
admet-512	187	9	115	115	NUM
admet-512	187	10	-	-	SYM
admet-512	187	11	129	129	NUM
admet-512	187	12	.	.	PUNCT
admet-512	188	1	[	[	X
admet-512	188	2	7	7	X
admet-512	188	3	]	]	PUNCT
admet-512	188	4	a.	a.	NOUN
admet-512	188	5	tezel	tezel	PROPN
admet-512	188	6	,	,	PUNCT
admet-512	188	7	s.	s.	PROPN
admet-512	188	8	mitragotri	mitragotri	PROPN
admet-512	188	9	.	.	PUNCT
admet-512	189	1	on	on	ADP
admet-512	189	2	the	the	DET
admet-512	189	3	origin	origin	NOUN
admet-512	189	4	of	of	ADP
admet-512	189	5	size	size	NOUN
admet-512	189	6	-	-	PUNCT
admet-512	189	7	dependent	dependent	ADJ
admet-512	189	8	tortuosity	tortuosity	NOUN
admet-512	189	9	for	for	ADP
admet-512	189	10	permeation	permeation	NOUN
admet-512	189	11	of	of	ADP
admet-512	189	12	hydrophilic	hydrophilic	ADJ
admet-512	189	13	solutes	solute	NOUN
admet-512	189	14	across	across	ADP
admet-512	189	15	the	the	DET
admet-512	189	16	stratum	stratum	NOUN
admet-512	189	17	corneum	corneum	NOUN
admet-512	189	18	.	.	PUNCT
admet-512	190	1	journal	journal	PROPN
admet-512	190	2	of	of	ADP
admet-512	190	3	controlled	control	VERB
admet-512	190	4	release	release	NOUN
admet-512	190	5	86	86	NUM
admet-512	190	6	(	(	PUNCT
admet-512	190	7	2003	2003	NUM
admet-512	190	8	)	)	PUNCT
admet-512	190	9	183	183	NUM
admet-512	190	10	-	-	SYM
admet-512	190	11	186	186	NUM
admet-512	190	12	.	.	PUNCT
admet-512	191	1	[	[	X
admet-512	191	2	8	8	NUM
admet-512	191	3	]	]	PUNCT
admet-512	191	4	a.	a.	NOUN
admet-512	191	5	wilschut	wilschut	PROPN
admet-512	191	6	,	,	PUNCT
admet-512	191	7	w.	w.	PROPN
admet-512	191	8	ten	ten	NUM
admet-512	191	9	berge	berge	NOUN
admet-512	191	10	,	,	PUNCT
admet-512	191	11	p.j	p.j	PROPN
admet-512	191	12	.	.	PROPN
admet-512	191	13	robinson	robinson	PROPN
admet-512	191	14	,	,	PUNCT
admet-512	191	15	t.e	t.e	PROPN
admet-512	191	16	.	.	PROPN
admet-512	191	17	mckone	mckone	NOUN
admet-512	191	18	.	.	PUNCT
admet-512	192	1	estimating	estimate	VERB
admet-512	192	2	skin	skin	NOUN
admet-512	192	3	permeation	permeation	NOUN
admet-512	192	4	.	.	PUNCT
admet-512	193	1	the	the	DET
admet-512	193	2	validation	validation	NOUN
admet-512	193	3	of	of	ADP
admet-512	193	4	five	five	NUM
admet-512	193	5	mathematical	mathematical	ADJ
admet-512	193	6	skin	skin	NOUN
admet-512	193	7	permeation	permeation	NOUN
admet-512	193	8	models	model	NOUN
admet-512	193	9	.	.	PUNCT
admet-512	194	1	chemosphere	chemosphere	PROPN
admet-512	194	2	30	30	NUM
admet-512	194	3	(	(	PUNCT
admet-512	194	4	1995	1995	NUM
admet-512	194	5	)	)	PUNCT
admet-512	194	6	1275	1275	NUM
admet-512	194	7	-	-	SYM
admet-512	194	8	1296	1296	NUM
admet-512	194	9	.	.	PUNCT
admet-512	195	1	[	[	X
admet-512	195	2	9	9	NUM
admet-512	195	3	]	]	X
admet-512	195	4	m.j	m.j	PROPN
admet-512	195	5	.	.	PROPN
admet-512	195	6	kamlet	kamlet	PROPN
admet-512	195	7	,	,	PUNCT
admet-512	195	8	r.m	r.m	PROPN
admet-512	195	9	.	.	PROPN
admet-512	195	10	doherty	doherty	PROPN
admet-512	195	11	,	,	PUNCT
admet-512	195	12	j.l.m	j.l.m	NOUN
admet-512	195	13	.	.	PUNCT
admet-512	195	14	abboud	abboud	PROPN
admet-512	195	15	,	,	PUNCT
admet-512	195	16	m.h	m.h	PROPN
admet-512	195	17	.	.	PROPN
admet-512	195	18	abraham	abraham	PROPN
admet-512	195	19	,	,	PUNCT
admet-512	195	20	r.w	r.w	PROPN
admet-512	195	21	.	.	PROPN
admet-512	195	22	taft	taft	PROPN
admet-512	195	23	.	.	PUNCT
admet-512	196	1	solubility	solubility	NOUN
admet-512	196	2	:	:	PUNCT
admet-512	196	3	a	a	DET
admet-512	196	4	new	new	ADJ
admet-512	196	5	look	look	NOUN
admet-512	196	6	.	.	PUNCT
admet-512	197	1	chemtech	chemtech	PROPN
admet-512	197	2	16(9	16(9	NUM
admet-512	197	3	)	)	PUNCT
admet-512	197	4	(	(	PUNCT
admet-512	197	5	1986	1986	NUM
admet-512	197	6	)	)	PUNCT
admet-512	197	7	566	566	NUM
admet-512	197	8	-	-	NUM
admet-512	197	9	576	576	NUM
admet-512	197	10	[	[	SYM
admet-512	197	11	10	10	NUM
admet-512	197	12	]	]	X
admet-512	197	13	m.h	m.h	PROPN
admet-512	197	14	.	.	PROPN
admet-512	197	15	abraham	abraham	PROPN
admet-512	197	16	.	.	PUNCT
admet-512	198	1	scales	scale	NOUN
admet-512	198	2	of	of	ADP
admet-512	198	3	solute	solute	ADJ
admet-512	198	4	hydrogen	hydrogen	NOUN
admet-512	198	5	-	-	PUNCT
admet-512	198	6	bonding	bonding	NOUN
admet-512	198	7	:	:	PUNCT
admet-512	198	8	their	their	PRON
admet-512	198	9	construction	construction	NOUN
admet-512	198	10	and	and	CCONJ
admet-512	198	11	application	application	NOUN
admet-512	198	12	to	to	ADP
admet-512	198	13	physicochemical	physicochemical	ADJ
admet-512	198	14	and	and	CCONJ
admet-512	198	15	biochemical	biochemical	ADJ
admet-512	198	16	processes	process	NOUN
admet-512	198	17	.	.	PUNCT
admet-512	199	1	chemical	chemical	NOUN
admet-512	199	2	society	society	PROPN
admet-512	199	3	reviews	review	VERB
admet-512	199	4	22	22	NUM
admet-512	199	5	(	(	PUNCT
admet-512	199	6	1993	1993	NUM
admet-512	199	7	)	)	PUNCT
admet-512	199	8	73	73	NUM
admet-512	199	9	-	-	SYM
admet-512	199	10	83	83	NUM
admet-512	199	11	.	.	PUNCT
admet-512	200	1	[	[	X
admet-512	200	2	11	11	NUM
admet-512	200	3	]	]	PUNCT
admet-512	200	4	m.	m.	NOUN
admet-512	200	5	vitha	vitha	PROPN
admet-512	200	6	,	,	PUNCT
admet-512	200	7	p.w	p.w	PROPN
admet-512	200	8	.	.	PROPN
admet-512	200	9	carr	carr	PROPN
admet-512	200	10	.	.	PUNCT
admet-512	201	1	the	the	DET
admet-512	201	2	chemical	chemical	NOUN
admet-512	201	3	interpretation	interpretation	NOUN
admet-512	201	4	and	and	CCONJ
admet-512	201	5	practice	practice	NOUN
admet-512	201	6	of	of	ADP
admet-512	201	7	linear	linear	ADJ
admet-512	201	8	solvation	solvation	NOUN
admet-512	201	9	energy	energy	NOUN
admet-512	201	10	relationships	relationship	NOUN
admet-512	201	11	in	in	ADP
admet-512	201	12	chromatography	chromatography	NOUN
admet-512	201	13	.	.	PUNCT
admet-512	202	1	journal	journal	PROPN
admet-512	202	2	of	of	ADP
admet-512	202	3	chromatography	chromatography	NOUN
admet-512	202	4	a	a	DET
admet-512	202	5	1126	1126	NUM
admet-512	202	6	(	(	PUNCT
admet-512	202	7	2006	2006	NUM
admet-512	202	8	)	)	PUNCT
admet-512	202	9	143	143	NUM
admet-512	202	10	-	-	SYM
admet-512	202	11	194	194	NUM
admet-512	202	12	.	.	PUNCT
admet-512	203	1	[	[	X
admet-512	203	2	12	12	NUM
admet-512	203	3	]	]	X
admet-512	203	4	m.h	m.h	PROPN
admet-512	203	5	.	.	PROPN
admet-512	203	6	abraham	abraham	PROPN
admet-512	203	7	,	,	PUNCT
admet-512	203	8	h.s	h.s	PROPN
admet-512	203	9	.	.	PROPN
admet-512	203	10	chadha	chadha	PROPN
admet-512	203	11	,	,	PUNCT
admet-512	203	12	f.	f.	PROPN
admet-512	203	13	martins	martins	PROPN
admet-512	203	14	,	,	PUNCT
admet-512	203	15	r.c	r.c	PROPN
admet-512	203	16	.	.	PROPN
admet-512	203	17	mitchell	mitchell	PROPN
admet-512	203	18	,	,	PUNCT
admet-512	203	19	m.w	m.w	PROPN
admet-512	203	20	.	.	PROPN
admet-512	203	21	bradbury	bradbury	PROPN
admet-512	203	22	,	,	PUNCT
admet-512	203	23	j.a	j.a	PROPN
admet-512	203	24	.	.	PROPN
admet-512	203	25	gratton	gratton	PROPN
admet-512	203	26	.	.	PUNCT
admet-512	204	1	hydrogen	hydrogen	NOUN
admet-512	204	2	bonding	bonding	NOUN
admet-512	204	3	part	part	NOUN
admet-512	204	4	46	46	NUM
admet-512	204	5	:	:	PUNCT
admet-512	204	6	a	a	DET
admet-512	204	7	review	review	NOUN
admet-512	204	8	of	of	ADP
admet-512	204	9	the	the	DET
admet-512	204	10	correlation	correlation	NOUN
admet-512	204	11	and	and	CCONJ
admet-512	204	12	prediction	prediction	NOUN
admet-512	204	13	of	of	ADP
admet-512	204	14	transport	transport	NOUN
admet-512	204	15	properties	property	NOUN
admet-512	204	16	by	by	ADP
admet-512	204	17	an	an	DET
admet-512	204	18	lfer	lfer	NOUN
admet-512	204	19	method	method	NOUN
admet-512	204	20	:	:	PUNCT
admet-512	204	21	physicochemical	physicochemical	ADJ
admet-512	204	22	properties	property	NOUN
admet-512	204	23	,	,	PUNCT
admet-512	204	24	brain	brain	NOUN
admet-512	204	25	penetration	penetration	NOUN
admet-512	204	26	and	and	CCONJ
admet-512	204	27	skin	skin	NOUN
admet-512	204	28	permeability	permeability	NOUN
admet-512	204	29	.	.	PUNCT
admet-512	205	1	pest	pest	NOUN
admet-512	205	2	management	management	NOUN
admet-512	205	3	science	science	NOUN
admet-512	205	4	55	55	NUM
admet-512	205	5	(	(	PUNCT
admet-512	205	6	1999	1999	NUM
admet-512	205	7	)	)	PUNCT
admet-512	205	8	78	78	NUM
admet-512	205	9	-	-	SYM
admet-512	205	10	88	88	NUM
admet-512	205	11	.	.	PUNCT
admet-512	206	1	[	[	X
admet-512	206	2	13	13	NUM
admet-512	206	3	]	]	X
admet-512	206	4	m.h	m.h	PROPN
admet-512	206	5	.	.	PROPN
admet-512	206	6	abraham	abraham	PROPN
admet-512	206	7	,	,	PUNCT
admet-512	206	8	chadha	chadha	PROPN
admet-512	206	9	,	,	PUNCT
admet-512	206	10	h.s	h.s	PROPN
admet-512	206	11	.	.	PROPN
admet-512	206	12	,	,	PUNCT
admet-512	206	13	mitchell	mitchell	PROPN
admet-512	206	14	,	,	PUNCT
admet-512	206	15	r.c	r.c	PROPN
admet-512	206	16	.	.	PROPN
admet-512	206	17	(	(	PUNCT
admet-512	206	18	1995b	1995b	NUM
admet-512	206	19	)	)	PUNCT
admet-512	206	20	.	.	PUNCT
admet-512	207	1	the	the	DET
admet-512	207	2	factors	factor	NOUN
admet-512	207	3	that	that	PRON
admet-512	207	4	influence	influence	VERB
admet-512	207	5	skin	skin	NOUN
admet-512	207	6	penetration	penetration	NOUN
admet-512	207	7	of	of	ADP
admet-512	207	8	solutes	solute	NOUN
admet-512	207	9	.	.	PUNCT
admet-512	207	10	journal	journal	NOUN
admet-512	207	11	of	of	ADP
admet-512	207	12	pharmacy	pharmacy	NOUN
admet-512	207	13	and	and	CCONJ
admet-512	207	14	pharmacology	pharmacology	NOUN
admet-512	207	15	,	,	PUNCT
admet-512	207	16	47	47	NUM
admet-512	207	17	,	,	PUNCT
admet-512	207	18	8	8	NUM
admet-512	207	19	-	-	SYM
admet-512	207	20	16	16	NUM
admet-512	207	21	.	.	PUNCT
admet-512	208	1	[	[	X
admet-512	208	2	14	14	NUM
admet-512	208	3	]	]	X
admet-512	208	4	m.h	m.h	PROPN
admet-512	208	5	.	.	PROPN
admet-512	208	6	abraham	abraham	PROPN
admet-512	208	7	,	,	PUNCT
admet-512	208	8	f.	f.	PROPN
admet-512	208	9	martins	martins	PROPN
admet-512	208	10	,	,	PUNCT
admet-512	208	11	r.c	r.c	PROPN
admet-512	208	12	.	.	PROPN
admet-512	208	13	mitchell	mitchell	PROPN
admet-512	208	14	.	.	PUNCT
admet-512	209	1	algorithms	algorithm	NOUN
admet-512	209	2	for	for	ADP
admet-512	209	3	skin	skin	NOUN
admet-512	209	4	permeability	permeability	NOUN
admet-512	209	5	using	use	VERB
admet-512	209	6	hydrogen	hydrogen	NOUN
admet-512	209	7	bond	bond	NOUN
admet-512	209	8	descriptors	descriptor	NOUN
admet-512	209	9	:	:	PUNCT
admet-512	209	10	the	the	DET
admet-512	209	11	problem	problem	NOUN
admet-512	209	12	of	of	ADP
admet-512	209	13	steroids	steroid	NOUN
admet-512	209	14	.	.	PUNCT
admet-512	210	1	journal	journal	PROPN
admet-512	210	2	of	of	ADP
admet-512	210	3	pharmacy	pharmacy	NOUN
admet-512	210	4	and	and	CCONJ
admet-512	210	5	pharmacology	pharmacology	NOUN
admet-512	210	6	49	49	NUM
admet-512	210	7	(	(	PUNCT
admet-512	210	8	1997	1997	NUM
admet-512	210	9	)	)	PUNCT
admet-512	210	10	858	858	NUM
admet-512	210	11	-	-	SYM
admet-512	210	12	865	865	NUM
admet-512	210	13	.	.	PUNCT
admet-512	211	1	[	[	X
admet-512	211	2	15	15	NUM
admet-512	211	3	]	]	X
admet-512	211	4	m.h	m.h	PROPN
admet-512	211	5	.	.	PROPN
admet-512	211	6	abraham	abraham	PROPN
admet-512	211	7	,	,	PUNCT
admet-512	211	8	f.	f.	PROPN
admet-512	211	9	martins	martins	PROPN
admet-512	211	10	.	.	PUNCT
admet-512	212	1	human	human	ADJ
admet-512	212	2	skin	skin	NOUN
admet-512	212	3	permeation	permeation	NOUN
admet-512	212	4	and	and	CCONJ
admet-512	212	5	partition	partition	NOUN
admet-512	212	6	:	:	PUNCT
admet-512	212	7	general	general	ADJ
admet-512	212	8	linear	linear	ADJ
admet-512	212	9	free	free	ADJ
admet-512	212	10	-	-	PUNCT
admet-512	212	11	energy	energy	NOUN
admet-512	212	12	relationship	relationship	NOUN
admet-512	212	13	analyses	analysis	NOUN
admet-512	212	14	.	.	PUNCT
admet-512	213	1	journal	journal	NOUN
admet-512	213	2	of	of	ADP
admet-512	213	3	pharmaceutical	pharmaceutical	NOUN
admet-512	213	4	sciences	science	NOUN
admet-512	213	5	93	93	NUM
admet-512	213	6	(	(	PUNCT
admet-512	213	7	2004	2004	NUM
admet-512	213	8	)	)	PUNCT
admet-512	213	9	1508	1508	NUM
admet-512	213	10	-	-	SYM
admet-512	213	11	1523	1523	NUM
admet-512	213	12	.	.	PUNCT
admet-512	214	1	[	[	X
admet-512	214	2	16	16	NUM
admet-512	214	3	]	]	PUNCT
admet-512	214	4	k.	k.	PROPN
admet-512	214	5	zhang	zhang	PROPN
admet-512	214	6	,	,	PUNCT
admet-512	214	7	m.	m.	PROPN
admet-512	214	8	chen	chen	PROPN
admet-512	214	9	,	,	PUNCT
admet-512	214	10	g.k.e	g.k.e	PROPN
admet-512	214	11	.	.	PUNCT
admet-512	214	12	scriba	scriba	PROPN
admet-512	214	13	,	,	PUNCT
admet-512	214	14	m.h	m.h	PROPN
admet-512	214	15	.	.	PROPN
admet-512	214	16	abraham	abraham	PROPN
admet-512	214	17	,	,	PUNCT
admet-512	214	18	a.	a.	PROPN
admet-512	214	19	fahr	fahr	PROPN
admet-512	214	20	,	,	PUNCT
admet-512	215	1	x.	x.	PROPN
admet-512	215	2	liu	liu	PROPN
admet-512	215	3	.	.	PUNCT
admet-512	216	1	human	human	ADJ
admet-512	216	2	skin	skin	NOUN
admet-512	216	3	permeation	permeation	NOUN
admet-512	216	4	of	of	ADP
admet-512	216	5	neutral	neutral	ADJ
admet-512	216	6	species	specie	NOUN
admet-512	216	7	and	and	CCONJ
admet-512	216	8	ionic	ionic	ADJ
admet-512	216	9	species	specie	NOUN
admet-512	216	10	:	:	PUNCT
admet-512	216	11	extended	extend	VERB
admet-512	216	12	linear	linear	ADJ
admet-512	216	13	free	free	ADJ
admet-512	216	14	-	-	PUNCT
admet-512	216	15	energy	energy	NOUN
admet-512	216	16	relationship	relationship	NOUN
admet-512	216	17	analyses	analysis	NOUN
admet-512	216	18	.	.	PUNCT
admet-512	217	1	journal	journal	NOUN
admet-512	217	2	of	of	ADP
admet-512	217	3	pharmaceutical	pharmaceutical	PROPN
admet-512	217	4	sciences	science	NOUN
admet-512	217	5	101	101	NUM
admet-512	217	6	(	(	PUNCT
admet-512	217	7	2012	2012	NUM
admet-512	217	8	)	)	PUNCT
admet-512	217	9	2034	2034	NUM
admet-512	217	10	-	-	SYM
admet-512	217	11	2044	2044	NUM
admet-512	217	12	.	.	PUNCT
admet-512	218	1	[	[	X
admet-512	218	2	17	17	NUM
admet-512	218	3	]	]	X
admet-512	218	4	b.j	b.j	PROPN
admet-512	218	5	.	.	PROPN
admet-512	218	6	neely	neely	PROPN
admet-512	218	7	,	,	PUNCT
admet-512	218	8	s.v	s.v	PROPN
admet-512	218	9	.	.	PROPN
admet-512	218	10	madihally	madihally	PROPN
admet-512	218	11	,	,	PUNCT
admet-512	218	12	r.l	r.l	PROPN
admet-512	218	13	.	.	PROPN
admet-512	218	14	robinson	robinson	PROPN
admet-512	218	15	jr	jr	PROPN
admet-512	218	16	,	,	PUNCT
admet-512	218	17	k.a.m	k.a.m	PROPN
admet-512	218	18	.	.	PROPN
admet-512	218	19	gasem	gasem	PROPN
admet-512	218	20	.	.	PUNCT
admet-512	219	1	nonlinear	nonlinear	ADJ
admet-512	219	2	quantitative	quantitative	ADJ
admet-512	219	3	structureproperty	structureproperty	NOUN
admet-512	219	4	relationship	relationship	NOUN
admet-512	219	5	modeling	modeling	NOUN
admet-512	219	6	of	of	ADP
admet-512	219	7	skin	skin	NOUN
admet-512	219	8	permeation	permeation	NOUN
admet-512	219	9	coefficient	coefficient	NOUN
admet-512	219	10	.	.	PUNCT
admet-512	220	1	journal	journal	PROPN
admet-512	220	2	of	of	ADP
admet-512	220	3	pharmaceutical	pharmaceutical	NOUN
admet-512	220	4	sciences	science	NOUN
admet-512	220	5	,	,	PUNCT
admet-512	220	6	98	98	NUM
admet-512	220	7	(	(	PUNCT
admet-512	220	8	2009	2009	NUM
admet-512	220	9	)	)	PUNCT
admet-512	220	10	4069	4069	NUM
admet-512	220	11	-	-	SYM
admet-512	220	12	4084	4084	NUM
admet-512	220	13	.	.	PUNCT
admet-512	221	1	[	[	X
admet-512	221	2	18	18	NUM
admet-512	221	3	]	]	X
admet-512	221	4	p.	p.	NOUN
admet-512	221	5	buchwald	buchwald	NOUN
admet-512	221	6	,	,	PUNCT
admet-512	221	7	n.	n.	PROPN
admet-512	221	8	bodor	bodor	PROPN
admet-512	221	9	.	.	PUNCT
admet-512	222	1	a	a	DET
admet-512	222	2	simple	simple	ADJ
admet-512	222	3	,	,	PUNCT
admet-512	222	4	predictive	predictive	ADJ
admet-512	222	5	,	,	PUNCT
admet-512	222	6	structure	structure	NOUN
admet-512	222	7	-	-	PUNCT
admet-512	222	8	based	base	VERB
admet-512	222	9	skin	skin	NOUN
admet-512	222	10	permeability	permeability	NOUN
admet-512	222	11	model	model	NOUN
admet-512	222	12	.	.	PUNCT
admet-512	223	1	journal	journal	PROPN
admet-512	223	2	of	of	ADP
admet-512	223	3	pharmacy	pharmacy	NOUN
admet-512	223	4	and	and	CCONJ
admet-512	223	5	pharmacology	pharmacology	NOUN
admet-512	223	6	53	53	NUM
admet-512	223	7	(	(	PUNCT
admet-512	223	8	2001	2001	NUM
admet-512	223	9	)	)	PUNCT
admet-512	223	10	1087	1087	NUM
admet-512	223	11	-	-	SYM
admet-512	223	12	1098	1098	NUM
admet-512	223	13	.	.	PUNCT
admet-512	224	1	[	[	X
admet-512	224	2	19	19	NUM
admet-512	224	3	]	]	X
admet-512	224	4	d.	d.	PROPN
admet-512	224	5	neumann	neumann	PROPN
admet-512	224	6	,	,	PUNCT
admet-512	224	7	o.	o.	PROPN
admet-512	224	8	kohlbacher	kohlbacher	PROPN
admet-512	224	9	,	,	PUNCT
admet-512	224	10	c.	c.	PROPN
admet-512	224	11	merkwirth	merkwirth	PROPN
admet-512	224	12	,	,	PUNCT
admet-512	224	13	t.	t.	PROPN
admet-512	224	14	lengauer	lengauer	PROPN
admet-512	224	15	.	.	PUNCT
admet-512	225	1	a	a	DET
admet-512	225	2	fully	fully	ADV
admet-512	225	3	computational	computational	ADJ
admet-512	225	4	model	model	NOUN
admet-512	225	5	for	for	ADP
admet-512	225	6	predicting	predict	VERB
admet-512	225	7	percutaneous	percutaneous	ADJ
admet-512	225	8	drug	drug	NOUN
admet-512	225	9	absorption	absorption	NOUN
admet-512	225	10	.	.	PUNCT
admet-512	226	1	journal	journal	PROPN
admet-512	226	2	of	of	ADP
admet-512	226	3	chemical	chemical	ADJ
admet-512	226	4	information	information	NOUN
admet-512	226	5	and	and	CCONJ
admet-512	226	6	modeling	model	VERB
admet-512	226	7	46	46	NUM
admet-512	226	8	(	(	PUNCT
admet-512	226	9	2006	2006	NUM
admet-512	226	10	)	)	PUNCT
admet-512	226	11	424	424	NUM
admet-512	226	12	-	-	SYM
admet-512	226	13	429	429	NUM
admet-512	226	14	.	.	PUNCT
admet-512	227	1	[	[	X
admet-512	227	2	20	20	NUM
admet-512	227	3	]	]	PUNCT
admet-512	227	4	m.	m.	NOUN
admet-512	227	5	hidalgo	hidalgo	PROPN
admet-512	227	6	-	-	PUNCT
admet-512	227	7	rodríguez	rodríguez	PROPN
admet-512	227	8	,	,	PUNCT
admet-512	227	9	s.	s.	PROPN
admet-512	227	10	soriano	soriano	PROPN
admet-512	227	11	-	-	PUNCT
admet-512	227	12	meseguer	meseguer	PROPN
admet-512	227	13	,	,	PUNCT
admet-512	227	14	e.	e.	PROPN
admet-512	227	15	fuguet	fuguet	PROPN
admet-512	227	16	,	,	PUNCT
admet-512	227	17	c.	c.	PROPN
admet-512	227	18	ràfols	ràfols	PROPN
admet-512	227	19	,	,	PUNCT
admet-512	227	20	m.	m.	NOUN
admet-512	227	21	rosés	rosés	PROPN
admet-512	227	22	.	.	PUNCT
admet-512	228	1	evaluation	evaluation	NOUN
admet-512	228	2	of	of	ADP
admet-512	228	3	the	the	DET
admet-512	228	4	suitability	suitability	NOUN
admet-512	228	5	of	of	ADP
admet-512	228	6	chromatographic	chromatographic	ADJ
admet-512	228	7	systems	system	NOUN
admet-512	228	8	to	to	PART
admet-512	228	9	predict	predict	VERB
admet-512	228	10	human	human	ADJ
admet-512	228	11	skin	skin	NOUN
admet-512	228	12	permeation	permeation	NOUN
admet-512	228	13	of	of	ADP
admet-512	228	14	neutral	neutral	ADJ
admet-512	228	15	compounds	compound	NOUN
admet-512	228	16	.	.	PUNCT
admet-512	229	1	european	european	ADJ
admet-512	229	2	journal	journal	PROPN
admet-512	229	3	of	of	ADP
admet-512	229	4	pharmaceutical	pharmaceutical	PROPN
admet-512	229	5	sciences	science	NOUN
admet-512	229	6	50(5	50(5	NUM
admet-512	229	7	)	)	PUNCT
admet-512	229	8	(	(	PUNCT
admet-512	229	9	2013	2013	NUM
admet-512	229	10	)	)	PUNCT
admet-512	229	11	557–568	557–568	NUM
admet-512	229	12	.	.	PUNCT
admet-512	230	1	[	[	X
admet-512	230	2	21	21	NUM
admet-512	230	3	]	]	X
admet-512	230	4	acd	acd	PROPN
admet-512	230	5	/	/	SYM
admet-512	230	6	percepta	percepta	NOUN
admet-512	230	7	,	,	PUNCT
admet-512	230	8	www.acdlabs.com	www.acdlabs.com	NOUN
admet-512	230	9	,	,	PUNCT
admet-512	230	10	advanced	advanced	ADJ
admet-512	230	11	chemistry	chemistry	NOUN
admet-512	230	12	development	development	NOUN
admet-512	230	13	,	,	PUNCT
admet-512	230	14	inc	inc	PROPN
admet-512	230	15	.	.	PROPN
admet-512	230	16	,	,	PUNCT
admet-512	230	17	release	release	NOUN
admet-512	230	18	(	(	PUNCT
admet-512	230	19	build	build	VERB
admet-512	230	20	2726	2726	NUM
admet-512	230	21	,	,	PUNCT
admet-512	230	22	5	5	NUM
admet-512	230	23	may	may	PROPN
admet-512	230	24	2014	2014	NUM
admet-512	230	25	)	)	PUNCT
admet-512	230	26	.	.	PUNCT
admet-512	231	1	[	[	X
admet-512	231	2	22	22	NUM
admet-512	231	3	]	]	X
admet-512	231	4	a.d	a.d	PROPN
admet-512	231	5	.	.	PROPN
admet-512	231	6	jones	jones	PROPN
admet-512	231	7	,	,	PUNCT
admet-512	231	8	i.p	i.p	PROPN
admet-512	231	9	.	.	PROPN
admet-512	231	10	dick	dick	PROPN
admet-512	231	11	,	,	PUNCT
admet-512	231	12	j.w	j.w	PROPN
admet-512	231	13	.	.	PROPN
admet-512	231	14	cherrie	cherrie	PROPN
admet-512	231	15	,	,	PUNCT
admet-512	231	16	m.t.d	m.t.d	PROPN
admet-512	231	17	.	.	PUNCT
admet-512	232	1	cronin	cronin	PROPN
admet-512	232	2	,	,	PUNCT
admet-512	232	3	j.j.m	j.j.m	PROPN
admet-512	232	4	.	.	PUNCT
admet-512	233	1	van	van	PROPN
admet-512	233	2	de	de	PROPN
admet-512	233	3	sandt	sandt	PROPN
admet-512	233	4	,	,	PUNCT
admet-512	233	5	d.j	d.j	PROPN
admet-512	233	6	.	.	PROPN
admet-512	233	7	esdaile	esdaile	PROPN
admet-512	233	8	,	,	PUNCT
admet-512	233	9	s.	s.	PROPN
admet-512	233	10	iyengar	iyengar	PROPN
admet-512	233	11	,	,	PUNCT
admet-512	233	12	w.	w.	PROPN
admet-512	233	13	ten	ten	NUM
admet-512	233	14	berge	berge	NOUN
admet-512	233	15	,	,	PUNCT
admet-512	233	16	s.c	s.c	PROPN
admet-512	233	17	.	.	PROPN
admet-512	233	18	wilkinson	wilkinson	PROPN
admet-512	233	19	,	,	PUNCT
admet-512	233	20	c.s	c.s	PROPN
admet-512	233	21	.	.	PROPN
admet-512	233	22	roper	roper	PROPN
admet-512	233	23	,	,	PUNCT
admet-512	233	24	s.	s.	PROPN
admet-512	233	25	semple	semple	PROPN
admet-512	233	26	,	,	PUNCT
admet-512	233	27	c.	c.	PROPN
admet-512	233	28	de	de	PROPN
admet-512	233	29	heer	heer	PROPN
admet-512	233	30	,	,	PUNCT
admet-512	233	31	f.m	f.m	PROPN
admet-512	233	32	.	.	PROPN
admet-512	233	33	williams	williams	PROPN
admet-512	233	34	.	.	PUNCT
admet-512	234	1	cefic	cefic	PROPN
admet-512	234	2	workshop	workshop	NOUN
admet-512	234	3	on	on	ADP
admet-512	234	4	methods	method	NOUN
admet-512	234	5	to	to	PART
admet-512	234	6	determine	determine	VERB
admet-512	234	7	dermal	dermal	ADJ
admet-512	234	8	permeation	permeation	NOUN
admet-512	234	9	for	for	ADP
admet-512	234	10	human	human	ADJ
admet-512	234	11	risk	risk	NOUN
admet-512	234	12	assessment	assessment	NOUN
admet-512	234	13	.	.	PUNCT
admet-512	235	1	european	european	ADJ
admet-512	235	2	chemical	chemical	PROPN
admet-512	235	3	industry	industry	PROPN
admet-512	235	4	council	council	PROPN
admet-512	235	5	,	,	PUNCT
admet-512	235	6	december	december	PROPN
admet-512	235	7	(	(	PUNCT
admet-512	235	8	2004	2004	NUM
admet-512	235	9	)	)	PUNCT
admet-512	236	1	pp	pp	ADP
admet-512	236	2	1–86	1–86	ADJ
admet-512	236	3	[	[	X
admet-512	236	4	23	23	NUM
admet-512	236	5	]	]	X
admet-512	236	6	j.j	j.j	PROPN
admet-512	236	7	.	.	PROPN
admet-512	236	8	van	van	PROPN
admet-512	236	9	de	de	PROPN
admet-512	236	10	sandt	sandt	PROPN
admet-512	236	11	,	,	PUNCT
admet-512	236	12	j.a	j.a	PROPN
admet-512	236	13	.	.	PROPN
admet-512	236	14	van	van	PROPN
admet-512	236	15	burgsteden	burgsteden	PROPN
admet-512	236	16	,	,	PUNCT
admet-512	236	17	s.	s.	PROPN
admet-512	236	18	cage	cage	PROPN
admet-512	236	19	,	,	PUNCT
admet-512	236	20	p.l	p.l	PROPN
admet-512	236	21	.	.	PROPN
admet-512	236	22	carmichael	carmichael	PROPN
admet-512	236	23	,	,	PUNCT
admet-512	236	24	i.	i.	PROPN
admet-512	236	25	dick	dick	PROPN
admet-512	236	26	,	,	PUNCT
admet-512	236	27	s.	s.	PROPN
admet-512	236	28	kenyon	kenyon	PROPN
admet-512	236	29	,	,	PUNCT
admet-512	236	30	g.	g.	PROPN
admet-512	236	31	korinth	korinth	PROPN
admet-512	236	32	,	,	PUNCT
admet-512	236	33	f.	f.	PROPN
admet-512	236	34	larese	larese	PROPN
admet-512	236	35	,	,	PUNCT
admet-512	236	36	j.c	j.c	PROPN
admet-512	236	37	.	.	PROPN
admet-512	236	38	limasset	limasset	PROPN
admet-512	236	39	,	,	PUNCT
admet-512	236	40	w.j	w.j	PROPN
admet-512	236	41	.	.	PROPN
admet-512	236	42	maas	maas	PROPN
admet-512	236	43	.	.	PUNCT
admet-512	237	1	in	in	ADP
admet-512	237	2	vitro	vitro	X
admet-512	237	3	predictions	prediction	NOUN
admet-512	237	4	of	of	ADP
admet-512	237	5	skin	skin	NOUN
admet-512	237	6	absorption	absorption	NOUN
admet-512	237	7	of	of	ADP
admet-512	237	8	caffeine	caffeine	NOUN
admet-512	237	9	,	,	PUNCT
admet-512	237	10	testosterone	testosterone	NOUN
admet-512	237	11	,	,	PUNCT
admet-512	237	12	and	and	CCONJ
admet-512	237	13	benzoic	benzoic	ADJ
admet-512	237	14	acid	acid	NOUN
admet-512	237	15	:	:	PUNCT
admet-512	237	16	a	a	DET
admet-512	237	17	multi	multi	ADJ
admet-512	237	18	-	-	ADJ
admet-512	237	19	centre	centre	ADJ
admet-512	237	20	comparison	comparison	NOUN
admet-512	237	21	study	study	NOUN
admet-512	237	22	.	.	PUNCT
admet-512	238	1	regulatory	regulatory	ADJ
admet-512	238	2	toxicology	toxicology	NOUN
admet-512	238	3	and	and	CCONJ
admet-512	238	4	pharmacology	pharmacology	NOUN
admet-512	238	5	39	39	NUM
admet-512	238	6	(	(	PUNCT
admet-512	238	7	2004	2004	NUM
admet-512	238	8	)	)	PUNCT
admet-512	239	1	271–281	271–281	NUM
admet-512	239	2	.	.	PUNCT
admet-512	239	3	http://www.acdlabs.com/	http://www.acdlabs.com/	PROPN
admet-512	239	4	marti	marti	PROPN
admet-512	239	5	rosés	rosés	PROPN
admet-512	239	6	et	et	PROPN
admet-512	239	7	al	al	PROPN
admet-512	239	8	admet	admet	PROPN
admet-512	239	9	&	&	CCONJ
admet-512	239	10	dmpk	dmpk	PROPN
admet-512	239	11	6(2	6(2	NUM
admet-512	239	12	)	)	PUNCT
admet-512	239	13	(	(	PUNCT
admet-512	239	14	2018	2018	NUM
admet-512	239	15	)	)	PUNCT
admet-512	239	16	140	140	NUM
admet-512	239	17	-	-	SYM
admet-512	239	18	152	152	NUM
admet-512	239	19	152	152	NUM
admet-512	239	20	[	[	X
admet-512	239	21	24	24	NUM
admet-512	239	22	]	]	SYM
admet-512	239	23	s.c	s.c	PROPN
admet-512	239	24	.	.	PROPN
admet-512	239	25	wilkinson	wilkinson	PROPN
admet-512	239	26	,	,	PUNCT
admet-512	239	27	w.j.m	w.j.m	PROPN
admet-512	239	28	.	.	PUNCT
admet-512	239	29	maas	maas	PROPN
admet-512	239	30	,	,	PUNCT
admet-512	239	31	j.b	j.b	PROPN
admet-512	239	32	.	.	PROPN
admet-512	239	33	nielsen	nielsen	PROPN
admet-512	239	34	,	,	PUNCT
admet-512	239	35	l.c	l.c	PROPN
admet-512	239	36	.	.	PROPN
admet-512	239	37	greaves	greave	NOUN
admet-512	239	38	,	,	PUNCT
admet-512	239	39	j.j.m	j.j.m	NOUN
admet-512	239	40	.	.	PUNCT
admet-512	240	1	van	van	PROPN
admet-512	240	2	de	de	PROPN
admet-512	240	3	sandt	sandt	PROPN
admet-512	240	4	,	,	PUNCT
admet-512	240	5	f.m	f.m	PROPN
admet-512	240	6	.	.	PROPN
admet-512	240	7	williams	williams	PROPN
admet-512	240	8	.	.	PUNCT
admet-512	241	1	interactions	interaction	NOUN
admet-512	241	2	of	of	ADP
admet-512	241	3	skin	skin	NOUN
admet-512	241	4	thickness	thickness	NOUN
admet-512	241	5	and	and	CCONJ
admet-512	241	6	physicochemical	physicochemical	ADJ
admet-512	241	7	properties	property	NOUN
admet-512	241	8	of	of	ADP
admet-512	241	9	test	test	NOUN
admet-512	241	10	compounds	compound	NOUN
admet-512	241	11	in	in	ADP
admet-512	241	12	percutaneous	percutaneous	ADJ
admet-512	241	13	penetration	penetration	NOUN
admet-512	241	14	studies	study	NOUN
admet-512	241	15	.	.	PUNCT
admet-512	242	1	international	international	ADJ
admet-512	242	2	archives	archive	NOUN
admet-512	242	3	of	of	ADP
admet-512	242	4	occupational	occupational	ADJ
admet-512	242	5	and	and	CCONJ
admet-512	242	6	environmental	environmental	ADJ
admet-512	242	7	health	health	NOUN
admet-512	242	8	79	79	NUM
admet-512	242	9	(	(	PUNCT
admet-512	242	10	2006	2006	NUM
admet-512	242	11	)	)	PUNCT
admet-512	242	12	405–413	405–413	NUM
admet-512	242	13	.	.	PUNCT
admet-512	243	1	[	[	X
admet-512	243	2	25	25	NUM
admet-512	243	3	]	]	X
admet-512	243	4	f.	f.	PROPN
admet-512	243	5	heuber	heuber	PROPN
admet-512	243	6	,	,	PUNCT
admet-512	243	7	f.	f.	PROPN
admet-512	243	8	ouvrard	ouvrard	PROPN
admet-512	243	9	-	-	PUNCT
admet-512	243	10	baraton	baraton	PROPN
admet-512	243	11	,	,	PUNCT
admet-512	243	12	j.p	j.p	PROPN
admet-512	243	13	.	.	PROPN
admet-512	243	14	biesse	biesse	PROPN
admet-512	243	15	,	,	PUNCT
admet-512	243	16	p.	p.	NOUN
admet-512	243	17	courtellemont	courtellemont	NOUN
admet-512	243	18	,	,	PUNCT
admet-512	243	19	c.m	c.m	PROPN
admet-512	243	20	.	.	PROPN
admet-512	243	21	vincent	vincent	PROPN
admet-512	243	22	,	,	PUNCT
admet-512	243	23	j.p	j.p	PROPN
admet-512	243	24	.	.	PROPN
admet-512	243	25	marty	marty	PROPN
admet-512	243	26	.	.	PUNCT
admet-512	244	1	pig	pig	PROPN
admet-512	244	2	ear	ear	VERB
admet-512	244	3	skin	skin	NOUN
admet-512	244	4	as	as	ADP
admet-512	244	5	a	a	DET
admet-512	244	6	model	model	NOUN
admet-512	244	7	for	for	ADP
admet-512	244	8	in	in	ADP
admet-512	244	9	vitro	vitro	X
admet-512	244	10	percutaneous	percutaneous	ADJ
admet-512	244	11	absorption	absorption	NOUN
admet-512	244	12	studies	study	NOUN
admet-512	244	13	:	:	PUNCT
admet-512	244	14	preliminary	preliminary	ADJ
admet-512	244	15	results	result	NOUN
admet-512	244	16	of	of	ADP
admet-512	244	17	an	an	DET
admet-512	244	18	inter	inter	ADJ
admet-512	244	19	-	-	ADJ
admet-512	244	20	laboratory	laboratory	ADJ
admet-512	244	21	validation	validation	NOUN
admet-512	244	22	.	.	PUNCT
admet-512	245	1	in	in	ADP
admet-512	245	2	:	:	PUNCT
admet-512	245	3	k.r	k.r	PROPN
admet-512	245	4	.	.	PROPN
admet-512	245	5	brain	brain	PROPN
admet-512	245	6	,	,	PUNCT
admet-512	245	7	k.a	k.a	PROPN
admet-512	245	8	.	.	PROPN
admet-512	245	9	walters	walters	PROPN
admet-512	245	10	,	,	PUNCT
admet-512	245	11	editors	editor	NOUN
admet-512	245	12	.	.	PUNCT
admet-512	245	13	perspectives	perspective	NOUN
admet-512	245	14	in	in	ADP
admet-512	245	15	percutaneous	percutaneous	ADJ
admet-512	245	16	penetration	penetration	NOUN
admet-512	245	17	,	,	PUNCT
admet-512	245	18	vol	vol	NOUN
admet-512	245	19	.	.	PUNCT
admet-512	245	20	6a	6a	NOUN
admet-512	245	21	.	.	PUNCT
admet-512	246	1	cardiff	cardiff	NOUN
admet-512	246	2	:	:	PUNCT
admet-512	246	3	sts	sts	PROPN
admet-512	246	4	publishing	publishing	PROPN
admet-512	246	5	ltd	ltd	PROPN
admet-512	246	6	(	(	PUNCT
admet-512	246	7	1998	1998	NUM
admet-512	246	8	)	)	PUNCT
admet-512	246	9	.	.	PUNCT
admet-512	247	1	[	[	X
admet-512	247	2	26	26	NUM
admet-512	247	3	]	]	X
admet-512	247	4	b.e	b.e	PROPN
admet-512	247	5	.	.	PROPN
admet-512	247	6	vecchia	vecchia	PROPN
admet-512	247	7	,	,	PUNCT
admet-512	247	8	a.l	a.l	PROPN
admet-512	247	9	.	.	PROPN
admet-512	247	10	bunge	bunge	PROPN
admet-512	247	11	.	.	PUNCT
admet-512	248	1	transdermal	transdermal	ADJ
admet-512	248	2	drug	drug	NOUN
admet-512	248	3	delivery	delivery	NOUN
admet-512	248	4	(	(	PUNCT
admet-512	248	5	pp	pp	ADJ
admet-512	248	6	.	.	PUNCT
admet-512	249	1	25–55	25–55	NUM
admet-512	249	2	)	)	PUNCT
admet-512	249	3	.	.	PUNCT
admet-512	250	1	new	new	PROPN
admet-512	250	2	york	york	PROPN
admet-512	250	3	:	:	PUNCT
admet-512	250	4	marcel	marcel	PROPN
admet-512	250	5	dekker	dekker	PROPN
admet-512	250	6	(	(	PUNCT
admet-512	250	7	2003	2003	NUM
admet-512	250	8	)	)	PUNCT
admet-512	250	9	.	.	PUNCT
admet-512	251	1	[	[	X
admet-512	251	2	27	27	NUM
admet-512	251	3	]	]	X
admet-512	251	4	h.	h.	PROPN
admet-512	251	5	baba	baba	PROPN
admet-512	251	6	,	,	PUNCT
admet-512	251	7	j.	j.	PROPN
admet-512	251	8	takahara	takahara	PROPN
admet-512	251	9	,	,	PUNCT
admet-512	251	10	h.	h.	PROPN
admet-512	251	11	mamitsuka	mamitsuka	PROPN
admet-512	251	12	.	.	PUNCT
admet-512	252	1	in	in	ADP
admet-512	252	2	silico	silico	NOUN
admet-512	252	3	predictions	prediction	NOUN
admet-512	252	4	of	of	ADP
admet-512	252	5	human	human	ADJ
admet-512	252	6	skin	skin	NOUN
admet-512	252	7	permeability	permeability	NOUN
admet-512	252	8	using	use	VERB
admet-512	252	9	nonlinear	nonlinear	ADJ
admet-512	252	10	quantitative	quantitative	ADJ
admet-512	252	11	structure	structure	NOUN
admet-512	252	12	-	-	PUNCT
admet-512	252	13	property	property	NOUN
admet-512	252	14	relationships	relationship	NOUN
admet-512	252	15	models	model	NOUN
admet-512	252	16	.	.	PUNCT
admet-512	253	1	pharmaceutical	pharmaceutical	ADJ
admet-512	253	2	research	research	NOUN
admet-512	253	3	32	32	NUM
admet-512	253	4	(	(	PUNCT
admet-512	253	5	2015	2015	NUM
admet-512	253	6	)	)	PUNCT
admet-512	253	7	23602371	23602371	NUM
admet-512	253	8	.	.	PUNCT
admet-512	254	1	[	[	X
admet-512	254	2	28	28	NUM
admet-512	254	3	]	]	X
admet-512	254	4	k.	k.	PROPN
admet-512	254	5	roy	roy	PROPN
admet-512	254	6	.	.	PROPN
admet-512	255	1	on	on	ADP
admet-512	255	2	some	some	DET
admet-512	255	3	aspects	aspect	NOUN
admet-512	255	4	of	of	ADP
admet-512	255	5	validation	validation	NOUN
admet-512	255	6	of	of	ADP
admet-512	255	7	predictive	predictive	ADJ
admet-512	255	8	quantitative	quantitative	ADJ
admet-512	255	9	structure	structure	NOUN
admet-512	255	10	–	–	PUNCT
admet-512	255	11	activity	activity	NOUN
admet-512	255	12	relationship	relationship	NOUN
admet-512	255	13	models	model	NOUN
admet-512	255	14	.	.	PUNCT
admet-512	256	1	expert	expert	ADJ
admet-512	256	2	opinion	opinion	NOUN
admet-512	256	3	on	on	ADP
admet-512	256	4	drug	drug	NOUN
admet-512	256	5	discovery	discovery	PROPN
admet-512	256	6	2(12	2(12	NUM
admet-512	256	7	)	)	PUNCT
admet-512	256	8	(	(	PUNCT
admet-512	256	9	2007	2007	NUM
admet-512	256	10	)	)	PUNCT
admet-512	256	11	1567–1577	1567–1577	NUM
admet-512	256	12	.	.	PUNCT
admet-512	257	1	[	[	X
admet-512	257	2	29	29	NUM
admet-512	257	3	]	]	PUNCT
admet-512	257	4	a.	a.	NOUN
admet-512	257	5	tropsha	tropsha	PROPN
admet-512	257	6	,	,	PUNCT
admet-512	257	7	p.	p.	PROPN
admet-512	257	8	gramatica	gramatica	PROPN
admet-512	257	9	,	,	PUNCT
admet-512	257	10	v.	v.	ADP
admet-512	257	11	gombar	gombar	NOUN
admet-512	257	12	.	.	PUNCT
admet-512	258	1	the	the	DET
admet-512	258	2	importance	importance	NOUN
admet-512	258	3	of	of	ADP
admet-512	258	4	being	be	AUX
admet-512	258	5	earnest	earnest	ADJ
admet-512	258	6	:	:	PUNCT
admet-512	258	7	validation	validation	NOUN
admet-512	258	8	is	be	AUX
admet-512	258	9	the	the	DET
admet-512	258	10	absolute	absolute	ADJ
admet-512	258	11	essential	essential	ADJ
admet-512	258	12	for	for	ADP
admet-512	258	13	successful	successful	ADJ
admet-512	258	14	application	application	NOUN
admet-512	258	15	and	and	CCONJ
admet-512	258	16	interpretation	interpretation	NOUN
admet-512	258	17	of	of	ADP
admet-512	258	18	qspr	qspr	NOUN
admet-512	258	19	models	model	NOUN
admet-512	258	20	.	.	PUNCT
admet-512	259	1	qsar	qsar	PROPN
admet-512	259	2	&	&	CCONJ
admet-512	259	3	combinatorial	combinatorial	PROPN
admet-512	259	4	science	science	PROPN
admet-512	259	5	22(1	22(1	NUM
admet-512	259	6	)	)	PUNCT
admet-512	259	7	(	(	PUNCT
admet-512	259	8	2003	2003	NUM
admet-512	259	9	)	)	PUNCT
admet-512	259	10	69–77	69–77	NUM
admet-512	259	11	.	.	PUNCT
admet-512	260	1	©	©	PROPN
admet-512	260	2	2018	2018	NUM
admet-512	260	3	by	by	ADP
admet-512	260	4	the	the	DET
admet-512	260	5	authors	author	NOUN
admet-512	260	6	;	;	PUNCT
admet-512	261	1	licensee	licensee	PROPN
admet-512	261	2	iapc	iapc	PROPN
admet-512	261	3	,	,	PUNCT
admet-512	261	4	zagreb	zagreb	PROPN
admet-512	261	5	,	,	PUNCT
admet-512	261	6	croatia	croatia	PROPN
admet-512	261	7	.	.	PUNCT
admet-512	262	1	this	this	DET
admet-512	262	2	article	article	NOUN
admet-512	262	3	is	be	AUX
admet-512	262	4	an	an	DET
admet-512	262	5	open	open	ADJ
admet-512	262	6	-	-	PUNCT
admet-512	262	7	access	access	NOUN
admet-512	262	8	article	article	NOUN
admet-512	262	9	distributed	distribute	VERB
admet-512	262	10	under	under	ADP
admet-512	262	11	the	the	DET
admet-512	262	12	terms	term	NOUN
admet-512	262	13	and	and	CCONJ
admet-512	262	14	conditions	condition	NOUN
admet-512	262	15	of	of	ADP
admet-512	262	16	the	the	DET
admet-512	262	17	creative	creative	ADJ
admet-512	262	18	commons	common	NOUN
admet-512	262	19	attribution	attribution	NOUN
admet-512	262	20	license	license	NOUN
admet-512	262	21	(	(	PUNCT
admet-512	262	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-512	262	23	)	)	PUNCT
admet-512	262	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN