id	sid	tid	token	lemma	pos
admet-520	1	1	peptide	peptide	ADJ
admet-520	1	2	retention	retention	NOUN
admet-520	1	3	time	time	NOUN
admet-520	1	4	prediction	prediction	NOUN
admet-520	1	5	for	for	ADP
admet-520	1	6	immobilized	immobilized	ADJ
admet-520	1	7	artificial	artificial	ADJ
admet-520	1	8	membrane	membrane	NOUN
admet-520	1	9	phosphatidylcholine	phosphatidylcholine	NOUN
admet-520	1	10	stationary	stationary	ADJ
admet-520	1	11	phase	phase	NOUN
admet-520	1	12	:	:	PUNCT
admet-520	1	13	method	method	NOUN
admet-520	1	14	development	development	NOUN
admet-520	1	15	and	and	CCONJ
admet-520	1	16	preliminary	preliminary	ADJ
admet-520	1	17	observations	observation	NOUN
admet-520	1	18	doi	doi	NOUN
admet-520	1	19	:	:	PUNCT
admet-520	1	20	10.5599	10.5599	NUM
admet-520	1	21	/	/	SYM
admet-520	1	22	admet.520	admet.520	PROPN
admet-520	1	23	190	190	NUM
admet-520	1	24	admet	admet	NOUN
admet-520	1	25	&	&	CCONJ
admet-520	1	26	dmpk	dmpk	PROPN
admet-520	1	27	6(2	6(2	NUM
admet-520	1	28	)	)	PUNCT
admet-520	1	29	(	(	PUNCT
admet-520	1	30	2018	2018	NUM
admet-520	1	31	)	)	PUNCT
admet-520	1	32	190	190	NUM
admet-520	1	33	-	-	SYM
admet-520	1	34	199	199	NUM
admet-520	1	35	;	;	PUNCT
admet-520	1	36	doi	doi	NOUN
admet-520	1	37	:	:	PUNCT
admet-520	1	38	http://dx.doi.org/10.5599/admet.520	http://dx.doi.org/10.5599/admet.520	NOUN
admet-520	1	39	open	open	ADJ
admet-520	1	40	access	access	NOUN
admet-520	1	41	:	:	PUNCT
admet-520	1	42	issn	issn	PROPN
admet-520	1	43	:	:	PUNCT
admet-520	1	44	1848	1848	NUM
admet-520	1	45	-	-	SYM
admet-520	1	46	7718	7718	NUM
admet-520	1	47	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-520	1	48	original	original	ADJ
admet-520	1	49	scientific	scientific	ADJ
admet-520	1	50	paper	paper	NOUN
admet-520	1	51	peptide	peptide	NOUN
admet-520	1	52	retention	retention	NOUN
admet-520	1	53	time	time	NOUN
admet-520	1	54	prediction	prediction	NOUN
admet-520	1	55	for	for	ADP
admet-520	1	56	immobilized	immobilized	ADJ
admet-520	1	57	artificial	artificial	ADJ
admet-520	1	58	membrane	membrane	NOUN
admet-520	1	59	phosphatidylcholine	phosphatidylcholine	NOUN
admet-520	1	60	stationary	stationary	ADJ
admet-520	1	61	phase	phase	NOUN
admet-520	1	62	:	:	PUNCT
admet-520	1	63	method	method	NOUN
admet-520	1	64	development	development	NOUN
admet-520	1	65	and	and	CCONJ
admet-520	1	66	preliminary	preliminary	ADJ
admet-520	1	67	observations	observation	NOUN
admet-520	1	68	daniel	daniel	PROPN
admet-520	1	69	gussakovsky1	gussakovsky1	PROPN
admet-520	1	70	,	,	PUNCT
admet-520	1	71	haley	haley	NOUN
admet-520	1	72	neustaeter1	neustaeter1	PROPN
admet-520	1	73	,	,	PUNCT
admet-520	1	74	victor	victor	PROPN
admet-520	1	75	spicer2	spicer2	PROPN
admet-520	1	76	,	,	PUNCT
admet-520	1	77	oleg	oleg	PROPN
admet-520	1	78	v.	v.	ADP
admet-520	1	79	krokhin2,3	krokhin2,3	PROPN
admet-520	1	80	*	*	PROPN
admet-520	1	81	1	1	NUM
admet-520	1	82	department	department	NOUN
admet-520	1	83	of	of	ADP
admet-520	1	84	chemistry	chemistry	NOUN
admet-520	1	85	,	,	PUNCT
admet-520	1	86	university	university	PROPN
admet-520	1	87	of	of	ADP
admet-520	1	88	manitoba	manitoba	PROPN
admet-520	1	89	,	,	PUNCT
admet-520	1	90	360	360	NUM
admet-520	1	91	parker	parker	PROPN
admet-520	1	92	building	building	PROPN
admet-520	1	93	,	,	PUNCT
admet-520	1	94	winnipeg	winnipeg	PROPN
admet-520	1	95	,	,	PUNCT
admet-520	1	96	manitoba	manitoba	PROPN
admet-520	1	97	r3	r3	PROPN
admet-520	1	98	t	t	PROPN
admet-520	1	99	2n2	2n2	NUM
admet-520	1	100	,	,	PUNCT
admet-520	1	101	canada	canada	PROPN
admet-520	1	102	2	2	NUM
admet-520	1	103	manitoba	manitoba	PROPN
admet-520	1	104	centre	centre	PROPN
admet-520	1	105	for	for	ADP
admet-520	1	106	proteomics	proteomic	NOUN
admet-520	1	107	and	and	CCONJ
admet-520	1	108	systems	system	NOUN
admet-520	1	109	biology	biology	NOUN
admet-520	1	110	,	,	PUNCT
admet-520	1	111	university	university	PROPN
admet-520	1	112	of	of	ADP
admet-520	1	113	manitoba	manitoba	PROPN
admet-520	1	114	,	,	PUNCT
admet-520	1	115	799	799	NUM
admet-520	1	116	jbrc	jbrc	NOUN
admet-520	1	117	,	,	PUNCT
admet-520	1	118	715	715	NUM
admet-520	1	119	mcdermot	mcdermot	PROPN
admet-520	1	120	avenue	avenue	PROPN
admet-520	1	121	,	,	PUNCT
admet-520	1	122	winnipeg	winnipeg	PROPN
admet-520	1	123	,	,	PUNCT
admet-520	1	124	manitoba	manitoba	PROPN
admet-520	1	125	r3e	r3e	PROPN
admet-520	1	126	3p4	3p4	NUM
admet-520	1	127	,	,	PUNCT
admet-520	1	128	canada	canada	PROPN
admet-520	1	129	3	3	NUM
admet-520	1	130	department	department	PROPN
admet-520	1	131	of	of	ADP
admet-520	1	132	internal	internal	ADJ
admet-520	1	133	medicine	medicine	NOUN
admet-520	1	134	,	,	PUNCT
admet-520	1	135	university	university	PROPN
admet-520	1	136	of	of	ADP
admet-520	1	137	manitoba	manitoba	PROPN
admet-520	1	138	,	,	PUNCT
admet-520	1	139	799	799	NUM
admet-520	1	140	jbrc	jbrc	NOUN
admet-520	1	141	,	,	PUNCT
admet-520	1	142	715	715	NUM
admet-520	1	143	mcdermot	mcdermot	PROPN
admet-520	1	144	avenue	avenue	PROPN
admet-520	1	145	,	,	PUNCT
admet-520	1	146	winnipeg	winnipeg	PROPN
admet-520	1	147	,	,	PUNCT
admet-520	1	148	manitoba	manitoba	PROPN
admet-520	1	149	r3e	r3e	PROPN
admet-520	1	150	3p4	3p4	NUM
admet-520	1	151	,	,	PUNCT
admet-520	1	152	canada	canada	PROPN
admet-520	1	153	*	*	PUNCT
admet-520	1	154	corresponding	correspond	VERB
admet-520	1	155	author	author	NOUN
admet-520	1	156	:	:	PUNCT
admet-520	2	1	e	e	NOUN
admet-520	2	2	-	-	NOUN
admet-520	2	3	mail	mail	NOUN
admet-520	2	4	:	:	PUNCT
admet-520	2	5	oleg.krokhine@umanitoba.ca	oleg.krokhine@umanitoba.ca	VERB
admet-520	2	6	;	;	PUNCT
admet-520	2	7	tel	tel	PROPN
admet-520	2	8	.	.	PUNCT
admet-520	2	9	:	:	PUNCT
admet-520	3	1	+1	+1	PROPN
admet-520	3	2	-	-	PUNCT
admet-520	3	3	204	204	NUM
admet-520	3	4	-	-	PUNCT
admet-520	3	5	789	789	NUM
admet-520	3	6	-	-	NUM
admet-520	3	7	3283	3283	NUM
admet-520	3	8	;	;	PUNCT
admet-520	3	9	fax	fax	NOUN
admet-520	3	10	:	:	PUNCT
admet-520	3	11	+1	+1	PROPN
admet-520	3	12	-	-	PUNCT
admet-520	3	13	204	204	NUM
admet-520	3	14	-	-	PUNCT
admet-520	3	15	480	480	NUM
admet-520	3	16	-	-	PUNCT
admet-520	3	17	1362	1362	NUM
admet-520	3	18	received	receive	VERB
admet-520	3	19	:	:	PUNCT
admet-520	3	20	march	march	PROPN
admet-520	3	21	14	14	NUM
admet-520	3	22	,	,	PUNCT
admet-520	3	23	2018	2018	NUM
admet-520	3	24	;	;	PUNCT
admet-520	3	25	revised	revise	VERB
admet-520	3	26	:	:	PUNCT
admet-520	3	27	may	may	AUX
admet-520	3	28	16	16	NUM
admet-520	3	29	,	,	PUNCT
admet-520	3	30	2018	2018	NUM
admet-520	3	31	;	;	PUNCT
admet-520	3	32	available	available	ADJ
admet-520	3	33	online	online	ADV
admet-520	3	34	:	:	PUNCT
admet-520	3	35	may	may	AUX
admet-520	3	36	24	24	NUM
admet-520	3	37	,	,	PUNCT
admet-520	3	38	2018	2018	NUM
admet-520	3	39	abstract	abstract	ADJ
admet-520	3	40	development	development	NOUN
admet-520	3	41	of	of	ADP
admet-520	3	42	the	the	DET
admet-520	3	43	first	first	ADJ
admet-520	3	44	peptide	peptide	NOUN
admet-520	3	45	retention	retention	NOUN
admet-520	3	46	prediction	prediction	NOUN
admet-520	3	47	model	model	NOUN
admet-520	3	48	for	for	ADP
admet-520	3	49	immobilized	immobilized	ADJ
admet-520	3	50	artificial	artificial	ADJ
admet-520	3	51	membrane	membrane	NOUN
admet-520	3	52	phosphatidylcholine	phosphatidylcholine	NOUN
admet-520	3	53	(	(	PUNCT
admet-520	3	54	iam.pc	iam.pc	NOUN
admet-520	3	55	)	)	PUNCT
admet-520	3	56	stationary	stationary	ADJ
admet-520	3	57	phase	phase	NOUN
admet-520	3	58	is	be	AUX
admet-520	3	59	reported	report	VERB
admet-520	3	60	.	.	PUNCT
admet-520	4	1	2d	2d	NUM
admet-520	4	2	liquid	liquid	ADJ
admet-520	4	3	chromatography	chromatography	NOUN
admet-520	4	4	coupled	couple	VERB
admet-520	4	5	to	to	PART
admet-520	4	6	tandem	tandem	VERB
admet-520	4	7	mass	mass	ADJ
admet-520	4	8	spectrometry	spectrometry	NOUN
admet-520	4	9	(	(	PUNCT
admet-520	4	10	2d	2d	PROPN
admet-520	4	11	lc	lc	PROPN
admet-520	4	12	-	-	PUNCT
admet-520	4	13	ms	ms	PROPN
admet-520	4	14	/	/	SYM
admet-520	4	15	ms	ms	NOUN
admet-520	4	16	)	)	PUNCT
admet-520	4	17	analysis	analysis	NOUN
admet-520	4	18	of	of	ADP
admet-520	4	19	a	a	DET
admet-520	4	20	whole	whole	ADJ
admet-520	4	21	cell	cell	NOUN
admet-520	4	22	lysate	lysate	NOUN
admet-520	4	23	of	of	ADP
admet-520	4	24	s.	s.	PROPN
admet-520	4	25	cerevisiae	cerevisiae	PROPN
admet-520	4	26	yielded	yield	VERB
admet-520	4	27	a	a	DET
admet-520	4	28	retention	retention	NOUN
admet-520	4	29	dataset	dataset	NOUN
admet-520	4	30	of	of	ADP
admet-520	4	31	~29,500	~29,500	X
admet-520	4	32	tryptic	tryptic	ADJ
admet-520	4	33	peptides	peptide	NOUN
admet-520	4	34	;	;	PUNCT
admet-520	4	35	sufficient	sufficient	ADJ
admet-520	4	36	for	for	ADP
admet-520	4	37	confident	confident	ADJ
admet-520	4	38	assignment	assignment	NOUN
admet-520	4	39	of	of	ADP
admet-520	4	40	retention	retention	NOUN
admet-520	4	41	coefficients	coefficient	NOUN
admet-520	4	42	which	which	PRON
admet-520	4	43	determine	determine	VERB
admet-520	4	44	the	the	DET
admet-520	4	45	contribution	contribution	NOUN
admet-520	4	46	of	of	ADP
admet-520	4	47	individual	individual	ADJ
admet-520	4	48	amino	amino	ADJ
admet-520	4	49	acids	acid	NOUN
admet-520	4	50	in	in	ADP
admet-520	4	51	peptide	peptide	ADJ
admet-520	4	52	retention	retention	NOUN
admet-520	4	53	.	.	PUNCT
admet-520	5	1	retention	retention	NOUN
admet-520	5	2	data	datum	NOUN
admet-520	5	3	from	from	ADP
admet-520	5	4	the	the	DET
admet-520	5	5	first	first	ADJ
admet-520	5	6	dimension	dimension	NOUN
admet-520	5	7	was	be	AUX
admet-520	5	8	used	use	VERB
admet-520	5	9	for	for	ADP
admet-520	5	10	the	the	DET
admet-520	5	11	modelling	modelling	NOUN
admet-520	5	12	:	:	PUNCT
admet-520	5	13	an	an	DET
admet-520	5	14	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	5	15	column	column	NOUN
admet-520	5	16	,	,	PUNCT
admet-520	5	17	with	with	ADP
admet-520	5	18	ph	ph	ADJ
admet-520	5	19	7.4	7.4	NUM
admet-520	5	20	ammonium	ammonium	NOUN
admet-520	5	21	bicarbonate	bicarbonate	NOUN
admet-520	5	22	,	,	PUNCT
admet-520	5	23	and	and	CCONJ
admet-520	5	24	a	a	DET
admet-520	5	25	water	water	NOUN
admet-520	5	26	/	/	SYM
admet-520	5	27	acetonitrile	acetonitrile	NOUN
admet-520	5	28	gradient	gradient	NOUN
admet-520	5	29	.	.	PUNCT
admet-520	6	1	peptide	peptide	NOUN
admet-520	6	2	separation	separation	NOUN
admet-520	6	3	using	use	VERB
admet-520	6	4	the	the	DET
admet-520	6	5	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	6	6	phase	phase	NOUN
admet-520	6	7	was	be	AUX
admet-520	6	8	compared	compare	VERB
admet-520	6	9	to	to	ADP
admet-520	6	10	a	a	DET
admet-520	6	11	standard	standard	ADJ
admet-520	6	12	c18	c18	NOUN
admet-520	6	13	phase	phase	NOUN
admet-520	6	14	(	(	PUNCT
admet-520	6	15	luna	luna	PROPN
admet-520	6	16	c18(2	c18(2	PROPN
admet-520	6	17	)	)	PUNCT
admet-520	6	18	)	)	PUNCT
admet-520	6	19	.	.	PUNCT
admet-520	7	1	there	there	PRON
admet-520	7	2	was	be	VERB
admet-520	7	3	a	a	DET
admet-520	7	4	significant	significant	ADJ
admet-520	7	5	reduction	reduction	NOUN
admet-520	7	6	in	in	ADP
admet-520	7	7	peptide	peptide	ADJ
admet-520	7	8	retention	retention	NOUN
admet-520	7	9	(	(	PUNCT
admet-520	7	10	~14	~14	PRON
admet-520	7	11	%	%	NOUN
admet-520	7	12	acetonitrile	acetonitrile	NOUN
admet-520	7	13	on	on	ADP
admet-520	7	14	average	average	ADJ
admet-520	7	15	)	)	PUNCT
admet-520	7	16	,	,	PUNCT
admet-520	7	17	indicating	indicate	VERB
admet-520	7	18	that	that	SCONJ
admet-520	7	19	the	the	DET
admet-520	7	20	phosphatidylcholine	phosphatidylcholine	NOUN
admet-520	7	21	stationary	stationary	ADJ
admet-520	7	22	phase	phase	NOUN
admet-520	7	23	is	be	AUX
admet-520	7	24	significantly	significantly	ADV
admet-520	7	25	more	more	ADV
admet-520	7	26	hydrophilic	hydrophilic	ADJ
admet-520	7	27	.	.	PUNCT
admet-520	8	1	in	in	ADP
admet-520	8	2	comparison	comparison	NOUN
admet-520	8	3	to	to	ADP
admet-520	8	4	the	the	DET
admet-520	8	5	c18	c18	NOUN
admet-520	8	6	phase	phase	NOUN
admet-520	8	7	,	,	PUNCT
admet-520	8	8	a	a	DET
admet-520	8	9	substantial	substantial	ADJ
admet-520	8	10	increase	increase	NOUN
admet-520	8	11	was	be	AUX
admet-520	8	12	found	find	VERB
admet-520	8	13	in	in	ADP
admet-520	8	14	the	the	DET
admet-520	8	15	relative	relative	ADJ
admet-520	8	16	retention	retention	NOUN
admet-520	8	17	contribution	contribution	NOUN
admet-520	8	18	for	for	ADP
admet-520	8	19	the	the	DET
admet-520	8	20	positively	positively	ADV
admet-520	8	21	charged	charge	VERB
admet-520	8	22	arg	arg	NOUN
admet-520	8	23	and	and	CCONJ
admet-520	8	24	lys	lys	PROPN
admet-520	8	25	,	,	PUNCT
admet-520	8	26	and	and	CCONJ
admet-520	8	27	the	the	DET
admet-520	8	28	aromatic	aromatic	ADJ
admet-520	8	29	tyr	tyr	PROPN
admet-520	8	30	,	,	PUNCT
admet-520	8	31	trp	trp	PROPN
admet-520	8	32	and	and	CCONJ
admet-520	8	33	his	his	PRON
admet-520	8	34	residues	residue	NOUN
admet-520	8	35	.	.	PUNCT
admet-520	9	1	a	a	DET
admet-520	9	2	decrease	decrease	NOUN
admet-520	9	3	in	in	ADP
admet-520	9	4	retention	retention	NOUN
admet-520	9	5	contribution	contribution	NOUN
admet-520	9	6	was	be	AUX
admet-520	9	7	observed	observe	VERB
admet-520	9	8	for	for	ADP
admet-520	9	9	the	the	DET
admet-520	9	10	negatively	negatively	ADV
admet-520	9	11	charged	charge	VERB
admet-520	9	12	asp	asp	NOUN
admet-520	9	13	and	and	CCONJ
admet-520	9	14	glu	glu	PROPN
admet-520	9	15	.	.	PUNCT
admet-520	10	1	this	this	PRON
admet-520	10	2	indicates	indicate	VERB
admet-520	10	3	an	an	DET
admet-520	10	4	involvement	involvement	NOUN
admet-520	10	5	of	of	ADP
admet-520	10	6	electrostatic	electrostatic	ADJ
admet-520	10	7	interactions	interaction	NOUN
admet-520	10	8	with	with	ADP
admet-520	10	9	the	the	DET
admet-520	10	10	glycerophosphate	glycerophosphate	ADJ
admet-520	10	11	functional	functional	ADJ
admet-520	10	12	groups	group	NOUN
admet-520	10	13	,	,	PUNCT
admet-520	10	14	and	and	CCONJ
admet-520	10	15	possibly	possibly	ADV
admet-520	10	16	,	,	PUNCT
admet-520	10	17	delocalization	delocalization	NOUN
admet-520	10	18	effects	effect	NOUN
admet-520	10	19	from	from	ADP
admet-520	10	20	hydrogen	hydrogen	NOUN
admet-520	10	21	bonds	bond	NOUN
admet-520	10	22	between	between	ADP
admet-520	10	23	the	the	DET
admet-520	10	24	phosphate	phosphate	ADJ
admet-520	10	25	group	group	NOUN
admet-520	10	26	and	and	CCONJ
admet-520	10	27	the	the	DET
admet-520	10	28	aromatic	aromatic	ADJ
admet-520	10	29	side	side	NOUN
admet-520	10	30	chains	chain	NOUN
admet-520	10	31	in	in	ADP
admet-520	10	32	the	the	DET
admet-520	10	33	separation	separation	NOUN
admet-520	10	34	mechanism	mechanism	NOUN
admet-520	10	35	.	.	PUNCT
admet-520	11	1	keywords	keyword	NOUN
admet-520	11	2	peptide	peptide	VERB
admet-520	11	3	retention	retention	NOUN
admet-520	11	4	modelling	modelling	NOUN
admet-520	11	5	;	;	PUNCT
admet-520	11	6	immobilized	immobilize	VERB
admet-520	11	7	artificial	artificial	ADJ
admet-520	11	8	membrane	membrane	NOUN
admet-520	11	9	chromatography	chromatography	NOUN
admet-520	11	10	introduction	introduction	NOUN
admet-520	11	11	modern	modern	ADJ
admet-520	11	12	applications	application	NOUN
admet-520	11	13	of	of	ADP
admet-520	11	14	chromatography	chromatography	NOUN
admet-520	11	15	have	have	AUX
admet-520	11	16	spread	spread	VERB
admet-520	11	17	far	far	ADV
admet-520	11	18	beyond	beyond	ADP
admet-520	11	19	its	its	PRON
admet-520	11	20	original	original	ADJ
admet-520	11	21	role	role	NOUN
admet-520	11	22	as	as	ADP
admet-520	11	23	a	a	DET
admet-520	11	24	method	method	NOUN
admet-520	11	25	for	for	ADP
admet-520	11	26	preparative	preparative	ADJ
admet-520	11	27	separations	separation	NOUN
admet-520	11	28	.	.	PUNCT
admet-520	12	1	years	year	NOUN
admet-520	12	2	of	of	ADP
admet-520	12	3	development	development	NOUN
admet-520	12	4	have	have	AUX
admet-520	12	5	established	establish	VERB
admet-520	12	6	chromatography	chromatography	NOUN
admet-520	12	7	as	as	ADP
admet-520	12	8	a	a	DET
admet-520	12	9	leading	lead	VERB
admet-520	12	10	analytical	analytical	ADJ
admet-520	12	11	technique	technique	NOUN
admet-520	12	12	covering	cover	VERB
admet-520	12	13	virtually	virtually	ADV
admet-520	12	14	all	all	DET
admet-520	12	15	fields	field	NOUN
admet-520	12	16	of	of	ADP
admet-520	12	17	analytical	analytical	ADJ
admet-520	12	18	chemistry	chemistry	NOUN
admet-520	12	19	.	.	PUNCT
admet-520	13	1	the	the	DET
admet-520	13	2	contribution	contribution	NOUN
admet-520	13	3	by	by	ADP
admet-520	13	4	high	high	ADJ
admet-520	13	5	-	-	PUNCT
admet-520	13	6	performance	performance	NOUN
admet-520	13	7	liquid	liquid	ADJ
admet-520	13	8	chromatography	chromatography	NOUN
admet-520	13	9	(	(	PUNCT
admet-520	13	10	hplc	hplc	PROPN
admet-520	13	11	)	)	PUNCT
admet-520	13	12	into	into	ADP
admet-520	13	13	studying	study	VERB
admet-520	13	14	physicochemical	physicochemical	ADJ
admet-520	13	15	fundamentals	fundamental	NOUN
admet-520	13	16	of	of	ADP
admet-520	13	17	interactions	interaction	NOUN
admet-520	13	18	in	in	ADP
admet-520	13	19	heterogeneous	heterogeneous	ADJ
admet-520	13	20	biological	biological	ADJ
admet-520	13	21	systems	system	NOUN
admet-520	13	22	is	be	AUX
admet-520	13	23	also	also	ADV
admet-520	13	24	well	well	ADV
admet-520	13	25	appreciated	appreciated	ADJ
admet-520	13	26	.	.	PUNCT
admet-520	14	1	establishing	establish	VERB
admet-520	14	2	hydrophobicity	hydrophobicity	NOUN
admet-520	14	3	scales	scale	NOUN
admet-520	14	4	of	of	ADP
admet-520	14	5	amino	amino	ADJ
admet-520	14	6	acids	acid	NOUN
admet-520	15	1	[	[	X
admet-520	15	2	1	1	NUM
admet-520	15	3	]	]	PUNCT
admet-520	15	4	to	to	PART
admet-520	15	5	support	support	VERB
admet-520	15	6	original	original	ADJ
admet-520	15	7	hydrophobicity	hydrophobicity	NOUN
admet-520	15	8	measurement	measurement	NOUN
admet-520	15	9	data	datum	NOUN
admet-520	15	10	obtained	obtain	VERB
admet-520	15	11	by	by	ADP
admet-520	15	12	x	x	NOUN
admet-520	15	13	-	-	NOUN
admet-520	15	14	ray	ray	NOUN
admet-520	15	15	crystallography	crystallography	NOUN
admet-520	15	16	[	[	X
admet-520	15	17	2	2	NUM
admet-520	15	18	]	]	PUNCT
admet-520	15	19	and	and	CCONJ
admet-520	15	20	studying	study	VERB
admet-520	15	21	interactions	interaction	NOUN
admet-520	15	22	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-520	15	23	mailto:oleg.krokhine@umanitoba.ca	mailto:oleg.krokhine@umanitoba.ca	PROPN
admet-520	15	24	admet	admet	PROPN
admet-520	15	25	&	&	CCONJ
admet-520	15	26	dmpk	dmpk	PROPN
admet-520	15	27	6(2	6(2	NUM
admet-520	15	28	)	)	PUNCT
admet-520	15	29	(	(	PUNCT
admet-520	15	30	2018	2018	NUM
admet-520	15	31	)	)	PUNCT
admet-520	15	32	190	190	NUM
admet-520	15	33	-	-	SYM
admet-520	15	34	199	199	NUM
admet-520	15	35	peptide	peptide	NOUN
admet-520	15	36	retention	retention	NOUN
admet-520	15	37	time	time	NOUN
admet-520	15	38	prediction	prediction	NOUN
admet-520	15	39	for	for	ADP
admet-520	15	40	iam.pc	iam.pc	PROPN
admet-520	15	41	stationary	stationary	ADJ
admet-520	15	42	phases	phase	NOUN
admet-520	15	43	doi	doi	NOUN
admet-520	15	44	:	:	PUNCT
admet-520	15	45	10.5599	10.5599	NUM
admet-520	15	46	/	/	SYM
admet-520	15	47	admet.520	admet.520	ADJ
admet-520	15	48	191	191	NUM
admet-520	15	49	of	of	ADP
admet-520	15	50	various	various	ADJ
admet-520	15	51	substances	substance	NOUN
admet-520	15	52	in	in	ADP
admet-520	15	53	the	the	DET
admet-520	15	54	systems	system	NOUN
admet-520	15	55	mimicking	mimic	VERB
admet-520	15	56	real	real	ADJ
admet-520	15	57	biological	biological	ADJ
admet-520	15	58	environments	environment	NOUN
admet-520	16	1	[	[	X
admet-520	16	2	3	3	X
admet-520	16	3	]	]	PUNCT
admet-520	16	4	represent	represent	VERB
admet-520	16	5	some	some	PRON
admet-520	16	6	of	of	ADP
admet-520	16	7	the	the	DET
admet-520	16	8	most	most	ADV
admet-520	16	9	interesting	interesting	ADJ
admet-520	16	10	fundamental	fundamental	ADJ
admet-520	16	11	biochemical	biochemical	ADJ
admet-520	16	12	applications	application	NOUN
admet-520	16	13	of	of	ADP
admet-520	16	14	chromatography	chromatography	NOUN
admet-520	16	15	.	.	PUNCT
admet-520	17	1	the	the	DET
admet-520	17	2	latter	latter	ADJ
admet-520	17	3	,	,	PUNCT
admet-520	17	4	now	now	ADV
admet-520	17	5	known	know	VERB
admet-520	17	6	under	under	ADP
admet-520	17	7	the	the	DET
admet-520	17	8	broad	broad	ADJ
admet-520	17	9	term	term	NOUN
admet-520	17	10	of	of	ADP
admet-520	17	11	biomimetic	biomimetic	ADJ
admet-520	17	12	chromatography	chromatography	NOUN
admet-520	17	13	,	,	PUNCT
admet-520	17	14	has	have	AUX
admet-520	17	15	found	find	VERB
admet-520	17	16	applications	application	NOUN
admet-520	17	17	in	in	ADP
admet-520	17	18	developing	develop	VERB
admet-520	17	19	fast	fast	ADJ
admet-520	17	20	assays	assay	NOUN
admet-520	17	21	to	to	PART
admet-520	17	22	determine	determine	VERB
admet-520	17	23	lipophilicity	lipophilicity	NOUN
admet-520	17	24	,	,	PUNCT
admet-520	17	25	protein	protein	NOUN
admet-520	17	26	binding	binding	NOUN
admet-520	17	27	,	,	PUNCT
admet-520	17	28	and	and	CCONJ
admet-520	17	29	phospholipid	phospholipid	NOUN
admet-520	17	30	binding	bind	VERB
admet-520	17	31	–	–	PUNCT
admet-520	17	32	all	all	DET
admet-520	17	33	critically	critically	ADV
admet-520	17	34	important	important	ADJ
admet-520	17	35	parameters	parameter	NOUN
admet-520	17	36	in	in	ADP
admet-520	17	37	drug	drug	NOUN
admet-520	17	38	design	design	NOUN
admet-520	17	39	.	.	PUNCT
admet-520	18	1	measuring	measure	VERB
admet-520	18	2	the	the	DET
admet-520	18	3	retention	retention	NOUN
admet-520	18	4	properties	property	NOUN
admet-520	18	5	of	of	ADP
admet-520	18	6	molecules	molecule	NOUN
admet-520	18	7	on	on	ADP
admet-520	18	8	a	a	DET
admet-520	18	9	c18	c18	NOUN
admet-520	18	10	reversed	reverse	VERB
admet-520	18	11	-	-	PUNCT
admet-520	18	12	phase	phase	NOUN
admet-520	18	13	support	support	NOUN
admet-520	18	14	provides	provide	VERB
admet-520	18	15	information	information	NOUN
admet-520	18	16	on	on	ADP
admet-520	18	17	the	the	DET
admet-520	18	18	hydrophobicity	hydrophobicity	NOUN
admet-520	18	19	of	of	ADP
admet-520	18	20	these	these	DET
admet-520	18	21	molecules	molecule	NOUN
admet-520	18	22	.	.	PUNCT
admet-520	19	1	similar	similar	ADJ
admet-520	19	2	measurements	measurement	NOUN
admet-520	19	3	on	on	ADP
admet-520	19	4	phospholipid	phospholipid	NOUN
admet-520	19	5	-	-	PUNCT
admet-520	19	6	modified	modify	VERB
admet-520	19	7	phases	phase	NOUN
admet-520	19	8	such	such	ADJ
admet-520	19	9	as	as	ADP
admet-520	19	10	immobilized	immobilized	ADJ
admet-520	19	11	artificial	artificial	ADJ
admet-520	19	12	membrane	membrane	NOUN
admet-520	19	13	phosphatidylcholine	phosphatidylcholine	NOUN
admet-520	19	14	(	(	PUNCT
admet-520	19	15	iam.pc	iam.pc	NOUN
admet-520	19	16	)	)	PUNCT
admet-520	19	17	provide	provide	VERB
admet-520	19	18	more	more	ADV
admet-520	19	19	biologically	biologically	ADV
admet-520	19	20	relevant	relevant	ADJ
admet-520	19	21	information	information	NOUN
admet-520	19	22	on	on	ADP
admet-520	19	23	phospholipid	phospholipid	NOUN
admet-520	19	24	binding	bind	VERB
admet-520	19	25	,	,	PUNCT
admet-520	19	26	i.e.	i.e.	X
admet-520	19	27	cell	cell	NOUN
admet-520	19	28	membrane	membrane	NOUN
admet-520	19	29	permeability	permeability	NOUN
admet-520	19	30	[	[	X
admet-520	19	31	4	4	NUM
admet-520	19	32	]	]	PUNCT
admet-520	19	33	.	.	PUNCT
admet-520	20	1	reversed	reverse	VERB
admet-520	20	2	-	-	PUNCT
admet-520	20	3	phase	phase	NOUN
admet-520	20	4	hplc	hplc	NOUN
admet-520	20	5	has	have	AUX
admet-520	20	6	been	be	AUX
admet-520	20	7	pin	pin	NOUN
admet-520	20	8	-	-	PUNCT
admet-520	20	9	pointed	point	VERB
admet-520	20	10	as	as	ADP
admet-520	20	11	a	a	DET
admet-520	20	12	powerful	powerful	ADJ
admet-520	20	13	technique	technique	NOUN
admet-520	20	14	for	for	ADP
admet-520	20	15	elucidating	elucidate	VERB
admet-520	20	16	the	the	DET
admet-520	20	17	hydrophobicity	hydrophobicity	NOUN
admet-520	20	18	contribution	contribution	NOUN
admet-520	20	19	of	of	ADP
admet-520	20	20	individual	individual	ADJ
admet-520	20	21	amino	amino	ADJ
admet-520	20	22	acids	acid	NOUN
admet-520	21	1	[	[	X
admet-520	21	2	5	5	NUM
admet-520	21	3	]	]	PUNCT
admet-520	21	4	and	and	CCONJ
admet-520	21	5	the	the	DET
admet-520	21	6	interacting	interact	VERB
admet-520	21	7	domains	domain	NOUN
admet-520	21	8	between	between	ADP
admet-520	21	9	the	the	DET
admet-520	21	10	peptide	peptide	NOUN
admet-520	21	11	and	and	CCONJ
admet-520	21	12	hydrophobic	hydrophobic	NOUN
admet-520	21	13	surfaces	surface	NOUN
admet-520	21	14	[	[	X
admet-520	21	15	6	6	NUM
admet-520	21	16	]	]	PUNCT
admet-520	21	17	.	.	PUNCT
admet-520	22	1	houghten	houghten	PROPN
admet-520	23	1	[	[	X
admet-520	23	2	6	6	NUM
admet-520	23	3	-	-	SYM
admet-520	23	4	8	8	NUM
admet-520	23	5	]	]	PUNCT
admet-520	23	6	and	and	CCONJ
admet-520	23	7	hodges	hodge	NOUN
admet-520	23	8	’	'	PUNCT
admet-520	24	1	[	[	X
admet-520	24	2	9	9	NUM
admet-520	24	3	-	-	SYM
admet-520	24	4	11	11	NUM
admet-520	24	5	]	]	PUNCT
admet-520	24	6	were	be	AUX
admet-520	24	7	the	the	DET
admet-520	24	8	first	first	ADJ
admet-520	24	9	to	to	PART
admet-520	24	10	address	address	VERB
admet-520	24	11	the	the	DET
admet-520	24	12	influence	influence	NOUN
admet-520	24	13	of	of	ADP
admet-520	24	14	amphipathic	amphipathic	ADJ
admet-520	24	15	helicity	helicity	NOUN
admet-520	24	16	in	in	ADP
admet-520	24	17	the	the	DET
admet-520	24	18	stabilization	stabilization	NOUN
admet-520	24	19	of	of	ADP
admet-520	24	20	helical	helical	ADJ
admet-520	24	21	peptides	peptide	NOUN
admet-520	24	22	upon	upon	SCONJ
admet-520	24	23	contact	contact	NOUN
admet-520	24	24	with	with	ADP
admet-520	24	25	a	a	DET
admet-520	24	26	hydrophobic	hydrophobic	NOUN
admet-520	24	27	surface	surface	NOUN
admet-520	24	28	–	–	PUNCT
admet-520	24	29	a	a	DET
admet-520	24	30	key	key	ADJ
admet-520	24	31	mechanism	mechanism	NOUN
admet-520	24	32	in	in	ADP
admet-520	24	33	antimicrobial	antimicrobial	ADJ
admet-520	24	34	peptides	peptide	NOUN
admet-520	24	35	’	'	PUNCT
admet-520	24	36	action	action	NOUN
admet-520	24	37	[	[	X
admet-520	24	38	11	11	NUM
admet-520	24	39	]	]	PUNCT
admet-520	24	40	.	.	PUNCT
admet-520	25	1	studies	study	NOUN
admet-520	25	2	such	such	ADJ
admet-520	25	3	as	as	ADP
admet-520	25	4	this	this	PRON
admet-520	25	5	represent	represent	VERB
admet-520	25	6	a	a	DET
admet-520	25	7	perfect	perfect	ADJ
admet-520	25	8	example	example	NOUN
admet-520	25	9	of	of	ADP
admet-520	25	10	bridging	bridge	VERB
admet-520	25	11	the	the	DET
admet-520	25	12	gap	gap	NOUN
admet-520	25	13	between	between	ADP
admet-520	25	14	hplc	hplc	NOUN
admet-520	25	15	as	as	ADP
admet-520	25	16	a	a	DET
admet-520	25	17	method	method	NOUN
admet-520	25	18	of	of	ADP
admet-520	25	19	physicochemical	physicochemical	ADJ
admet-520	25	20	study	study	NOUN
admet-520	25	21	and	and	CCONJ
admet-520	25	22	drug	drug	NOUN
admet-520	25	23	development	development	NOUN
admet-520	25	24	.	.	PUNCT
admet-520	26	1	all	all	PRON
admet-520	26	2	of	of	ADP
admet-520	26	3	these	these	DET
admet-520	26	4	efforts	effort	NOUN
admet-520	26	5	have	have	AUX
admet-520	26	6	originated	originate	VERB
admet-520	26	7	from	from	ADP
admet-520	26	8	the	the	DET
admet-520	26	9	first	first	ADJ
admet-520	26	10	attempts	attempt	NOUN
admet-520	26	11	to	to	PART
admet-520	26	12	model	model	VERB
admet-520	26	13	/	/	SYM
admet-520	26	14	predict	predict	VERB
admet-520	26	15	peptide	peptide	NOUN
admet-520	26	16	behaviour	behaviour	NOUN
admet-520	26	17	in	in	ADP
admet-520	26	18	reversed	reversed	ADJ
admet-520	26	19	-	-	PUNCT
admet-520	26	20	phase	phase	NOUN
admet-520	26	21	liquid	liquid	ADJ
admet-520	26	22	chromatography	chromatography	NOUN
admet-520	26	23	(	(	PUNCT
admet-520	26	24	rplc	rplc	NOUN
admet-520	26	25	)	)	PUNCT
admet-520	27	1	[	[	X
admet-520	27	2	12,13	12,13	NUM
admet-520	27	3	]	]	PUNCT
admet-520	27	4	.	.	PUNCT
admet-520	28	1	the	the	DET
admet-520	28	2	goal	goal	NOUN
admet-520	28	3	of	of	ADP
admet-520	28	4	the	the	DET
admet-520	28	5	early	early	ADJ
admet-520	28	6	modelling	modelling	NOUN
admet-520	28	7	studies	study	NOUN
admet-520	28	8	was	be	AUX
admet-520	28	9	to	to	PART
admet-520	28	10	simplify	simplify	VERB
admet-520	28	11	method	method	NOUN
admet-520	28	12	development	development	NOUN
admet-520	28	13	for	for	ADP
admet-520	28	14	peptide	peptide	ADJ
admet-520	28	15	analytical	analytical	ADJ
admet-520	28	16	hplc	hplc	NOUN
admet-520	28	17	with	with	ADP
admet-520	28	18	uv	uv	NOUN
admet-520	28	19	detection	detection	NOUN
admet-520	28	20	.	.	PUNCT
admet-520	29	1	the	the	DET
admet-520	29	2	arrival	arrival	NOUN
admet-520	29	3	of	of	ADP
admet-520	29	4	high	high	ADJ
admet-520	29	5	-	-	PUNCT
admet-520	29	6	throughput	throughput	NOUN
admet-520	29	7	proteomic	proteomic	ADJ
admet-520	29	8	technology	technology	NOUN
admet-520	29	9	led	lead	VERB
admet-520	29	10	to	to	ADP
admet-520	29	11	the	the	DET
admet-520	29	12	expansion	expansion	NOUN
admet-520	29	13	of	of	ADP
admet-520	29	14	these	these	DET
admet-520	29	15	applications	application	NOUN
admet-520	29	16	into	into	ADP
admet-520	29	17	protein	protein	NOUN
admet-520	29	18	/	/	SYM
admet-520	29	19	peptide	peptide	NOUN
admet-520	29	20	identification	identification	NOUN
admet-520	29	21	[	[	X
admet-520	29	22	14	14	NUM
admet-520	29	23	]	]	PUNCT
admet-520	29	24	,	,	PUNCT
admet-520	29	25	development	development	NOUN
admet-520	29	26	of	of	ADP
admet-520	29	27	quantitative	quantitative	ADJ
admet-520	29	28	lc	lc	PROPN
admet-520	29	29	-	-	PUNCT
admet-520	29	30	ms	ms	NOUN
admet-520	29	31	methods	method	NOUN
admet-520	29	32	[	[	X
admet-520	29	33	15	15	NUM
admet-520	29	34	]	]	PUNCT
admet-520	29	35	,	,	PUNCT
admet-520	29	36	and	and	CCONJ
admet-520	29	37	the	the	DET
admet-520	29	38	guided	guide	VERB
admet-520	29	39	design	design	NOUN
admet-520	29	40	of	of	ADP
admet-520	29	41	multi	multi	ADJ
admet-520	29	42	-	-	ADJ
admet-520	29	43	dimensional	dimensional	ADJ
admet-520	29	44	peptide	peptide	NOUN
admet-520	29	45	separation	separation	NOUN
admet-520	29	46	systems	system	NOUN
admet-520	29	47	[	[	X
admet-520	29	48	16	16	NUM
admet-520	29	49	]	]	PUNCT
admet-520	29	50	.	.	PUNCT
admet-520	30	1	proteomics	proteomic	NOUN
admet-520	30	2	has	have	AUX
admet-520	30	3	provided	provide	VERB
admet-520	30	4	a	a	DET
admet-520	30	5	significant	significant	ADJ
admet-520	30	6	increase	increase	NOUN
admet-520	30	7	in	in	ADP
admet-520	30	8	the	the	DET
admet-520	30	9	size	size	NOUN
admet-520	30	10	of	of	ADP
admet-520	30	11	peptide	peptide	ADJ
admet-520	30	12	retention	retention	NOUN
admet-520	30	13	data	datum	NOUN
admet-520	30	14	,	,	PUNCT
admet-520	30	15	paving	pave	VERB
admet-520	30	16	the	the	DET
admet-520	30	17	way	way	NOUN
admet-520	30	18	for	for	ADP
admet-520	30	19	the	the	DET
admet-520	30	20	development	development	NOUN
admet-520	30	21	of	of	ADP
admet-520	30	22	the	the	DET
admet-520	30	23	first	first	ADJ
admet-520	30	24	sequence	sequence	NOUN
admet-520	30	25	-	-	PUNCT
admet-520	30	26	specific	specific	ADJ
admet-520	30	27	peptide	peptide	NOUN
admet-520	30	28	retention	retention	NOUN
admet-520	30	29	prediction	prediction	NOUN
admet-520	30	30	models	model	NOUN
admet-520	30	31	[	[	X
admet-520	30	32	17	17	NUM
admet-520	30	33	-	-	SYM
admet-520	30	34	19	19	NUM
admet-520	30	35	]	]	PUNCT
admet-520	30	36	.	.	PUNCT
admet-520	31	1	the	the	DET
admet-520	31	2	majority	majority	NOUN
admet-520	31	3	of	of	ADP
admet-520	31	4	retention	retention	NOUN
admet-520	31	5	modelling	model	VERB
admet-520	31	6	studies	study	NOUN
admet-520	31	7	in	in	ADP
admet-520	31	8	the	the	DET
admet-520	31	9	proteomics	proteomic	NOUN
admet-520	31	10	era	era	NOUN
admet-520	31	11	targeted	target	VERB
admet-520	31	12	rplc	rplc	NOUN
admet-520	31	13	separations	separation	NOUN
admet-520	31	14	with	with	ADP
admet-520	31	15	formic	formic	ADJ
admet-520	31	16	acid	acid	NOUN
admet-520	31	17	as	as	ADP
admet-520	31	18	the	the	DET
admet-520	31	19	ion	ion	NOUN
admet-520	31	20	-	-	PUNCT
admet-520	31	21	pairing	pair	VERB
admet-520	31	22	modifier	modifier	NOUN
admet-520	31	23	.	.	PUNCT
admet-520	32	1	our	our	PRON
admet-520	32	2	sequence	sequence	NOUN
admet-520	32	3	-	-	PUNCT
admet-520	32	4	specific	specific	ADJ
admet-520	32	5	retention	retention	NOUN
admet-520	32	6	calculator	calculator	NOUN
admet-520	32	7	(	(	PUNCT
admet-520	32	8	ssrcalc	ssrcalc	NOUN
admet-520	32	9	)	)	PUNCT
admet-520	32	10	model	model	NOUN
admet-520	32	11	has	have	AUX
admet-520	32	12	been	be	AUX
admet-520	32	13	a	a	DET
admet-520	32	14	benchmark	benchmark	ADJ
admet-520	32	15	tool	tool	NOUN
admet-520	32	16	in	in	ADP
admet-520	32	17	this	this	DET
admet-520	32	18	field	field	NOUN
admet-520	32	19	since	since	SCONJ
admet-520	32	20	2004	2004	NUM
admet-520	32	21	(	(	PUNCT
admet-520	32	22	available	available	ADJ
admet-520	32	23	on	on	ADP
admet-520	32	24	-	-	PUNCT
admet-520	32	25	line	line	NOUN
admet-520	32	26	at	at	ADP
admet-520	32	27	http://hs2.proteome.ca/ssrcalc/ssrcalcq.html	http://hs2.proteome.ca/ssrcalc/ssrcalcq.html	NOUN
admet-520	32	28	)	)	PUNCT
admet-520	32	29	,	,	PUNCT
admet-520	32	30	and	and	CCONJ
admet-520	32	31	followed	follow	VERB
admet-520	32	32	the	the	DET
admet-520	32	33	same	same	ADJ
admet-520	32	34	trend	trend	NOUN
admet-520	32	35	but	but	CCONJ
admet-520	32	36	with	with	ADP
admet-520	32	37	the	the	DET
admet-520	32	38	addition	addition	NOUN
admet-520	32	39	of	of	ADP
admet-520	32	40	models	model	NOUN
admet-520	32	41	for	for	ADP
admet-520	32	42	trifluoroacetic	trifluoroacetic	ADJ
admet-520	32	43	acid	acid	NOUN
admet-520	32	44	[	[	X
admet-520	32	45	19	19	NUM
admet-520	32	46	]	]	PUNCT
admet-520	32	47	and	and	CCONJ
admet-520	32	48	high	high	ADJ
admet-520	32	49	ph	ph	ADJ
admet-520	32	50	reversed	reverse	VERB
admet-520	32	51	-	-	PUNCT
admet-520	32	52	phase	phase	NOUN
admet-520	32	53	[	[	X
admet-520	32	54	20	20	NUM
admet-520	32	55	]	]	PUNCT
admet-520	32	56	.	.	PUNCT
admet-520	33	1	other	other	ADJ
admet-520	33	2	peptide	peptide	NOUN
admet-520	33	3	separation	separation	NOUN
admet-520	33	4	modes	mode	NOUN
admet-520	33	5	have	have	AUX
admet-520	33	6	largely	largely	ADV
admet-520	33	7	excluded	exclude	VERB
admet-520	33	8	because	because	SCONJ
admet-520	33	9	of	of	ADP
admet-520	33	10	the	the	DET
admet-520	33	11	poor	poor	ADJ
admet-520	33	12	compatibility	compatibility	NOUN
admet-520	33	13	of	of	ADP
admet-520	33	14	the	the	DET
admet-520	33	15	eluents	eluent	NOUN
admet-520	33	16	with	with	ADP
admet-520	33	17	esi	esi	PROPN
admet-520	33	18	-	-	PROPN
admet-520	33	19	ms	ms	PROPN
admet-520	33	20	.	.	PROPN
admet-520	33	21	however	however	ADV
admet-520	33	22	,	,	PUNCT
admet-520	33	23	the	the	DET
admet-520	33	24	last	last	ADJ
admet-520	33	25	few	few	ADJ
admet-520	33	26	years	year	NOUN
admet-520	33	27	have	have	AUX
admet-520	33	28	witnessed	witness	VERB
admet-520	33	29	an	an	DET
admet-520	33	30	expansion	expansion	NOUN
admet-520	33	31	of	of	ADP
admet-520	33	32	prediction	prediction	NOUN
admet-520	33	33	studies	study	NOUN
admet-520	33	34	into	into	ADP
admet-520	33	35	other	other	ADJ
admet-520	33	36	separation	separation	NOUN
admet-520	33	37	mechanisms	mechanism	NOUN
admet-520	33	38	.	.	PUNCT
admet-520	34	1	in	in	ADP
admet-520	34	2	2017	2017	NUM
admet-520	34	3	our	our	PRON
admet-520	34	4	laboratory	laboratory	NOUN
admet-520	34	5	applied	apply	VERB
admet-520	34	6	ssrcalc	ssrcalc	ADJ
admet-520	34	7	methodology	methodology	NOUN
admet-520	34	8	to	to	ADP
admet-520	34	9	hydrophilic	hydrophilic	ADJ
admet-520	34	10	interaction	interaction	NOUN
admet-520	34	11	liquid	liquid	ADJ
admet-520	34	12	chromatography	chromatography	NOUN
admet-520	34	13	(	(	PUNCT
admet-520	34	14	hilic	hilic	NOUN
admet-520	34	15	)	)	PUNCT
admet-520	35	1	[	[	X
admet-520	35	2	21	21	NUM
admet-520	35	3	]	]	X
admet-520	35	4	,	,	PUNCT
admet-520	35	5	strong	strong	ADJ
admet-520	35	6	-	-	PUNCT
admet-520	35	7	cation	cation	NOUN
admet-520	35	8	exchange	exchange	NOUN
admet-520	35	9	(	(	PUNCT
admet-520	35	10	scx	scx	PROPN
admet-520	35	11	)	)	PUNCT
admet-520	36	1	[	[	X
admet-520	36	2	22	22	NUM
admet-520	36	3	]	]	PUNCT
admet-520	36	4	,	,	PUNCT
admet-520	36	5	strong	strong	ADJ
admet-520	36	6	-	-	PUNCT
admet-520	36	7	anion	anion	NOUN
admet-520	36	8	exchange	exchange	NOUN
admet-520	36	9	(	(	PUNCT
admet-520	36	10	sax	sax	NOUN
admet-520	36	11	)	)	PUNCT
admet-520	36	12	(	(	PUNCT
admet-520	36	13	manuscript	manuscript	NOUN
admet-520	36	14	in	in	ADP
admet-520	36	15	preparation	preparation	NOUN
admet-520	36	16	)	)	PUNCT
admet-520	36	17	,	,	PUNCT
admet-520	36	18	and	and	CCONJ
admet-520	36	19	capillary	capillary	ADJ
admet-520	36	20	zone	zone	NOUN
admet-520	36	21	electrophoresis	electrophoresis	NOUN
admet-520	36	22	(	(	PUNCT
admet-520	36	23	cze	cze	NOUN
admet-520	36	24	)	)	PUNCT
admet-520	37	1	[	[	X
admet-520	37	2	23	23	NUM
admet-520	37	3	]	]	PUNCT
admet-520	37	4	.	.	PUNCT
admet-520	38	1	all	all	PRON
admet-520	38	2	of	of	ADP
admet-520	38	3	the	the	DET
admet-520	38	4	listed	list	VERB
admet-520	38	5	prediction	prediction	NOUN
admet-520	38	6	models	model	NOUN
admet-520	38	7	that	that	PRON
admet-520	38	8	we	we	PRON
admet-520	38	9	have	have	AUX
admet-520	38	10	generated	generate	VERB
admet-520	38	11	are	be	AUX
admet-520	38	12	the	the	DET
admet-520	38	13	most	most	ADV
admet-520	38	14	accurate	accurate	ADJ
admet-520	38	15	models	model	NOUN
admet-520	38	16	reported	report	VERB
admet-520	38	17	for	for	ADP
admet-520	38	18	the	the	DET
admet-520	38	19	respective	respective	ADJ
admet-520	38	20	modes	mode	NOUN
admet-520	38	21	of	of	ADP
admet-520	38	22	peptide	peptide	ADJ
admet-520	38	23	separation	separation	NOUN
admet-520	38	24	.	.	PUNCT
admet-520	39	1	application	application	NOUN
admet-520	39	2	of	of	ADP
admet-520	39	3	2d	2d	PROPN
admet-520	39	4	lc	lc	PROPN
admet-520	39	5	-	-	PUNCT
admet-520	39	6	ms	ms	PROPN
admet-520	39	7	/	/	PROPN
admet-520	39	8	ms	ms	NOUN
admet-520	39	9	of	of	ADP
admet-520	39	10	the	the	DET
admet-520	39	11	complex	complex	ADJ
admet-520	39	12	tryptic	tryptic	ADJ
admet-520	39	13	digests	digest	NOUN
admet-520	39	14	was	be	AUX
admet-520	39	15	the	the	DET
admet-520	39	16	key	key	ADJ
admet-520	39	17	innovation	innovation	NOUN
admet-520	39	18	allowing	allow	VERB
admet-520	39	19	collection	collection	NOUN
admet-520	39	20	of	of	ADP
admet-520	39	21	large	large	ADJ
admet-520	39	22	retention	retention	NOUN
admet-520	39	23	datasets	dataset	NOUN
admet-520	39	24	for	for	ADP
admet-520	39	25	peptide	peptide	ADJ
admet-520	39	26	separations	separation	NOUN
admet-520	39	27	not	not	PART
admet-520	39	28	possible	possible	ADJ
admet-520	39	29	with	with	ADP
admet-520	39	30	on	on	ADP
admet-520	39	31	-	-	PUNCT
admet-520	39	32	line	line	NOUN
admet-520	39	33	esi	esi	PROPN
admet-520	39	34	-	-	ADJ
admet-520	39	35	ms	ms	ADJ
admet-520	39	36	detection	detection	NOUN
admet-520	39	37	[	[	X
admet-520	39	38	20	20	NUM
admet-520	39	39	,	,	PUNCT
admet-520	39	40	21	21	NUM
admet-520	39	41	]	]	PUNCT
admet-520	39	42	.	.	PUNCT
admet-520	40	1	standard	standard	PROPN
admet-520	40	2	rp	rp	PROPN
admet-520	40	3	(	(	PUNCT
admet-520	40	4	formic	formic	ADJ
admet-520	40	5	acid	acid	NOUN
admet-520	40	6	)	)	PUNCT
admet-520	40	7	lcms	lcms	PROPN
admet-520	40	8	/	/	SYM
admet-520	40	9	ms	ms	PROPN
admet-520	40	10	was	be	AUX
admet-520	40	11	used	use	VERB
admet-520	40	12	in	in	ADP
admet-520	40	13	the	the	DET
admet-520	40	14	second	second	ADJ
admet-520	40	15	dimension	dimension	NOUN
admet-520	40	16	as	as	ADP
admet-520	40	17	a	a	DET
admet-520	40	18	“	"	PUNCT
admet-520	40	19	standard	standard	ADJ
admet-520	40	20	detection	detection	NOUN
admet-520	40	21	device	device	NOUN
admet-520	40	22	”	"	PUNCT
admet-520	40	23	,	,	PUNCT
admet-520	40	24	while	while	SCONJ
admet-520	40	25	the	the	DET
admet-520	40	26	first	first	ADJ
admet-520	40	27	-	-	PUNCT
admet-520	40	28	dimension	dimension	NOUN
admet-520	40	29	separation	separation	NOUN
admet-520	40	30	information	information	NOUN
admet-520	40	31	was	be	AUX
admet-520	40	32	used	use	VERB
admet-520	40	33	as	as	ADP
admet-520	40	34	a	a	DET
admet-520	40	35	modelling	modelling	NOUN
admet-520	40	36	dataset	dataset	NOUN
admet-520	40	37	:	:	PUNCT
admet-520	40	38	e.g.	e.g.	ADV
admet-520	40	39	hilic	hilic	NOUN
admet-520	40	40	-	-	PUNCT
admet-520	40	41	rplc	rplc	NOUN
admet-520	40	42	-	-	NOUN
admet-520	40	43	ms	ms	NOUN
admet-520	40	44	for	for	ADP
admet-520	40	45	hilic	hilic	NOUN
admet-520	40	46	models	model	NOUN
admet-520	40	47	,	,	PUNCT
admet-520	40	48	scx	scx	NOUN
admet-520	40	49	-	-	PUNCT
admet-520	40	50	rplcms	rplcms	NOUN
admet-520	40	51	for	for	ADP
admet-520	40	52	scx	scx	NOUN
admet-520	40	53	,	,	PUNCT
admet-520	40	54	etc	etc	X
admet-520	40	55	.	.	X
admet-520	41	1	we	we	PRON
admet-520	41	2	are	be	AUX
admet-520	41	3	not	not	PART
admet-520	41	4	aware	aware	ADJ
admet-520	41	5	of	of	ADP
admet-520	41	6	any	any	DET
admet-520	41	7	peptide	peptide	ADJ
admet-520	41	8	retention	retention	NOUN
admet-520	41	9	modelling	model	VERB
admet-520	41	10	studies	study	NOUN
admet-520	41	11	on	on	ADP
admet-520	41	12	chromatographic	chromatographic	ADJ
admet-520	41	13	supports	support	NOUN
admet-520	41	14	for	for	ADP
admet-520	41	15	biomimetic	biomimetic	ADJ
admet-520	41	16	applications	application	NOUN
admet-520	41	17	.	.	PUNCT
admet-520	42	1	this	this	PRON
admet-520	42	2	would	would	AUX
admet-520	42	3	provide	provide	VERB
admet-520	42	4	a	a	DET
admet-520	42	5	significant	significant	ADJ
admet-520	42	6	advantage	advantage	NOUN
admet-520	42	7	by	by	ADP
admet-520	42	8	expanding	expand	VERB
admet-520	42	9	predictive	predictive	ADJ
admet-520	42	10	approaches	approach	NOUN
admet-520	42	11	to	to	ADP
admet-520	42	12	peptide	peptide	NOUN
admet-520	42	13	-	-	PUNCT
admet-520	42	14	based	base	VERB
admet-520	42	15	drug	drug	NOUN
admet-520	42	16	design	design	NOUN
admet-520	42	17	.	.	PUNCT
admet-520	43	1	having	have	VERB
admet-520	43	2	extensive	extensive	ADJ
admet-520	43	3	experience	experience	NOUN
admet-520	43	4	in	in	ADP
admet-520	43	5	peptide	peptide	ADJ
admet-520	43	6	retention	retention	NOUN
admet-520	43	7	modelling	modelling	NOUN
admet-520	43	8	in	in	ADP
admet-520	43	9	various	various	ADJ
admet-520	43	10	separation	separation	NOUN
admet-520	43	11	systems	system	NOUN
admet-520	43	12	,	,	PUNCT
admet-520	43	13	we	we	PRON
admet-520	43	14	concluded	conclude	VERB
admet-520	43	15	that	that	SCONJ
admet-520	43	16	the	the	DET
admet-520	43	17	use	use	NOUN
admet-520	43	18	of	of	ADP
admet-520	43	19	2d	2d	NUM
admet-520	43	20	iam.pc	iam.pc	PROPN
admet-520	43	21	-	-	PUNCT
admet-520	43	22	rplc	rplc	NOUN
admet-520	43	23	to	to	PART
admet-520	43	24	study	study	VERB
admet-520	43	25	peptide	peptide	NOUN
admet-520	43	26	separation	separation	NOUN
admet-520	43	27	in	in	ADP
admet-520	43	28	biomimetic	biomimetic	ADJ
admet-520	43	29	applications	application	NOUN
admet-520	43	30	would	would	AUX
admet-520	43	31	be	be	AUX
admet-520	43	32	the	the	DET
admet-520	43	33	first	first	ADJ
admet-520	43	34	step	step	NOUN
admet-520	43	35	in	in	ADP
admet-520	43	36	this	this	DET
admet-520	43	37	direction	direction	NOUN
admet-520	43	38	.	.	PUNCT
admet-520	44	1	the	the	DET
admet-520	44	2	goal	goal	NOUN
admet-520	44	3	of	of	ADP
admet-520	44	4	this	this	DET
admet-520	44	5	study	study	NOUN
admet-520	44	6	was	be	AUX
admet-520	44	7	to	to	PART
admet-520	44	8	establish	establish	VERB
admet-520	44	9	a	a	DET
admet-520	44	10	large	large	ADJ
admet-520	44	11	-	-	PUNCT
admet-520	44	12	scale	scale	NOUN
admet-520	44	13	retention	retention	NOUN
admet-520	44	14	data	datum	NOUN
admet-520	44	15	collection	collection	NOUN
admet-520	44	16	protocol	protocol	NOUN
admet-520	44	17	for	for	ADP
admet-520	44	18	peptide	peptide	ADJ
admet-520	44	19	separation	separation	NOUN
admet-520	44	20	on	on	ADP
admet-520	44	21	the	the	DET
admet-520	44	22	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	44	23	stationary	stationary	ADJ
admet-520	44	24	phase	phase	NOUN
admet-520	44	25	http://hs2.proteome.ca/ssrcalc/ssrcalcq.html	http://hs2.proteome.ca/ssrcalc/ssrcalcq.html	NUM
admet-520	45	1	oleg	oleg	PROPN
admet-520	45	2	krokhin	krokhin	PROPN
admet-520	45	3	et	et	PROPN
admet-520	45	4	al	al	PROPN
admet-520	45	5	.	.	PROPN
admet-520	45	6	admet	admet	PROPN
admet-520	45	7	&	&	CCONJ
admet-520	45	8	dmpk	dmpk	PROPN
admet-520	45	9	6(2	6(2	NUM
admet-520	45	10	)	)	PUNCT
admet-520	45	11	(	(	PUNCT
admet-520	45	12	2018	2018	NUM
admet-520	45	13	)	)	PUNCT
admet-520	45	14	190	190	NUM
admet-520	45	15	-	-	SYM
admet-520	45	16	199	199	NUM
admet-520	45	17	192	192	NUM
admet-520	45	18	and	and	CCONJ
admet-520	45	19	gain	gain	VERB
admet-520	45	20	a	a	DET
admet-520	45	21	first	first	ADJ
admet-520	45	22	insight	insight	NOUN
admet-520	45	23	into	into	ADP
admet-520	45	24	peptide	peptide	ADJ
admet-520	45	25	retention	retention	NOUN
admet-520	45	26	mechanism	mechanism	NOUN
admet-520	45	27	in	in	ADP
admet-520	45	28	this	this	DET
admet-520	45	29	system	system	NOUN
admet-520	45	30	.	.	PUNCT
admet-520	46	1	this	this	PRON
admet-520	46	2	was	be	AUX
admet-520	46	3	done	do	VERB
admet-520	46	4	by	by	ADP
admet-520	46	5	developing	develop	VERB
admet-520	46	6	a	a	DET
admet-520	46	7	peptide	peptide	ADJ
admet-520	46	8	retention	retention	NOUN
admet-520	46	9	prediction	prediction	NOUN
admet-520	46	10	model	model	NOUN
admet-520	46	11	and	and	CCONJ
admet-520	46	12	assigning	assign	VERB
admet-520	46	13	contributions	contribution	NOUN
admet-520	46	14	of	of	ADP
admet-520	46	15	individual	individual	ADJ
admet-520	46	16	amino	amino	ADJ
admet-520	46	17	acids	acid	NOUN
admet-520	46	18	into	into	ADP
admet-520	46	19	peptide	peptide	ADJ
admet-520	46	20	retention	retention	NOUN
admet-520	46	21	.	.	PUNCT
admet-520	47	1	experimental	experimental	ADJ
admet-520	47	2	experimental	experimental	ADJ
admet-520	47	3	procedures	procedure	NOUN
admet-520	47	4	were	be	AUX
admet-520	47	5	identical	identical	ADJ
admet-520	47	6	to	to	ADP
admet-520	47	7	the	the	DET
admet-520	47	8	previously	previously	ADV
admet-520	47	9	reported	report	VERB
admet-520	47	10	modelling	model	VERB
admet-520	47	11	studies	study	NOUN
admet-520	47	12	of	of	ADP
admet-520	47	13	hilic	hilic	NOUN
admet-520	47	14	and	and	CCONJ
admet-520	47	15	scx	scx	NOUN
admet-520	47	16	[	[	X
admet-520	47	17	21	21	NUM
admet-520	47	18	,	,	PUNCT
admet-520	47	19	22	22	NUM
admet-520	47	20	]	]	PUNCT
admet-520	47	21	,	,	PUNCT
admet-520	47	22	except	except	SCONJ
admet-520	47	23	for	for	ADP
admet-520	47	24	the	the	DET
admet-520	47	25	chromatographic	chromatographic	ADJ
admet-520	47	26	parameters	parameter	NOUN
admet-520	47	27	(	(	PUNCT
admet-520	47	28	columns	column	NOUN
admet-520	47	29	and	and	CCONJ
admet-520	47	30	eluents	eluent	NOUN
admet-520	47	31	)	)	PUNCT
admet-520	47	32	in	in	ADP
admet-520	47	33	the	the	DET
admet-520	47	34	first	first	ADJ
admet-520	47	35	-	-	PUNCT
admet-520	47	36	dimension	dimension	NOUN
admet-520	47	37	separation	separation	NOUN
admet-520	47	38	.	.	PUNCT
admet-520	48	1	overall	overall	ADV
admet-520	48	2	,	,	PUNCT
admet-520	48	3	the	the	DET
admet-520	48	4	procedure	procedure	NOUN
admet-520	48	5	(	(	PUNCT
admet-520	48	6	figure	figure	NOUN
admet-520	48	7	1	1	NUM
admet-520	48	8	)	)	PUNCT
admet-520	48	9	included	include	VERB
admet-520	48	10	a	a	DET
admet-520	48	11	tryptic	tryptic	ADJ
admet-520	48	12	digestion	digestion	NOUN
admet-520	48	13	of	of	ADP
admet-520	48	14	the	the	DET
admet-520	48	15	whole	whole	ADJ
admet-520	48	16	cell	cell	NOUN
admet-520	48	17	s.	s.	PROPN
admet-520	48	18	cerevisiae	cerevisiae	PROPN
admet-520	48	19	extract	extract	NOUN
admet-520	48	20	,	,	PUNCT
admet-520	48	21	first	first	ADJ
admet-520	48	22	dimension	dimension	NOUN
admet-520	48	23	separation	separation	NOUN
admet-520	48	24	in	in	ADP
admet-520	48	25	a	a	DET
admet-520	48	26	reversed	reverse	VERB
admet-520	48	27	-	-	PUNCT
admet-520	48	28	phase	phase	NOUN
admet-520	48	29	mode	mode	NOUN
admet-520	48	30	using	use	VERB
admet-520	48	31	a	a	DET
admet-520	48	32	luna	luna	PROPN
admet-520	48	33	c18(2	c18(2	PROPN
admet-520	48	34	)	)	PUNCT
admet-520	48	35	or	or	CCONJ
admet-520	48	36	and	and	CCONJ
admet-520	48	37	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	48	38	column	column	NOUN
admet-520	48	39	,	,	PUNCT
admet-520	48	40	fraction	fraction	NOUN
admet-520	48	41	collection	collection	NOUN
admet-520	48	42	,	,	PUNCT
admet-520	48	43	and	and	CCONJ
admet-520	48	44	lc	lc	PROPN
admet-520	48	45	-	-	PUNCT
admet-520	48	46	ms	ms	PROPN
admet-520	48	47	/	/	SYM
admet-520	48	48	ms	ms	NOUN
admet-520	48	49	analysis	analysis	NOUN
admet-520	48	50	of	of	ADP
admet-520	48	51	the	the	DET
admet-520	48	52	individual	individual	ADJ
admet-520	48	53	fractions	fraction	NOUN
admet-520	48	54	followed	follow	VERB
admet-520	48	55	by	by	ADP
admet-520	48	56	peptide	peptide	ADJ
admet-520	48	57	identification	identification	NOUN
admet-520	48	58	using	use	VERB
admet-520	48	59	the	the	DET
admet-520	48	60	x!tandem	x!tandem	PROPN
admet-520	48	61	search	search	NOUN
admet-520	48	62	algorithm	algorithm	NOUN
admet-520	48	63	.	.	PUNCT
admet-520	49	1	figure	figure	NOUN
admet-520	49	2	1	1	NUM
admet-520	49	3	.	.	PUNCT
admet-520	50	1	overview	overview	NOUN
admet-520	50	2	of	of	ADP
admet-520	50	3	the	the	DET
admet-520	50	4	experimental	experimental	ADJ
admet-520	50	5	procedure	procedure	NOUN
admet-520	50	6	for	for	ADP
admet-520	50	7	the	the	DET
admet-520	50	8	large	large	ADJ
admet-520	50	9	-	-	PUNCT
admet-520	50	10	scale	scale	NOUN
admet-520	50	11	peptide	peptide	NOUN
admet-520	50	12	retention	retention	NOUN
admet-520	50	13	data	datum	NOUN
admet-520	50	14	collection	collection	NOUN
admet-520	50	15	using	use	VERB
admet-520	50	16	2d	2d	NUM
admet-520	50	17	lc	lc	PROPN
admet-520	50	18	-	-	PUNCT
admet-520	50	19	ms	ms	PROPN
admet-520	50	20	/	/	SYM
admet-520	50	21	ms	ms	PROPN
admet-520	50	22	.	.	PROPN
admet-520	50	23	materials	material	NOUN
admet-520	50	24	,	,	PUNCT
admet-520	50	25	chromatographic	chromatographic	ADJ
admet-520	50	26	columns	column	NOUN
admet-520	50	27	deionized	deionize	VERB
admet-520	50	28	water	water	NOUN
admet-520	50	29	and	and	CCONJ
admet-520	50	30	hplc	hplc	NOUN
admet-520	50	31	-	-	PUNCT
admet-520	50	32	grade	grade	NOUN
admet-520	50	33	acetonitrile	acetonitrile	NOUN
admet-520	50	34	were	be	AUX
admet-520	50	35	used	use	VERB
admet-520	50	36	for	for	ADP
admet-520	50	37	the	the	DET
admet-520	50	38	preparation	preparation	NOUN
admet-520	50	39	of	of	ADP
admet-520	50	40	the	the	DET
admet-520	50	41	eluents	eluent	NOUN
admet-520	50	42	.	.	PUNCT
admet-520	51	1	all	all	DET
admet-520	51	2	chemicals	chemical	NOUN
admet-520	51	3	were	be	AUX
admet-520	51	4	sourced	source	VERB
admet-520	51	5	from	from	ADP
admet-520	51	6	sigma	sigma	PROPN
admet-520	51	7	chemicals	chemical	NOUN
admet-520	51	8	(	(	PUNCT
admet-520	51	9	st	st	PROPN
admet-520	51	10	.	.	PROPN
admet-520	51	11	louis	louis	PROPN
admet-520	51	12	,	,	PUNCT
admet-520	51	13	mo	mo	NOUN
admet-520	51	14	)	)	PUNCT
admet-520	51	15	unless	unless	SCONJ
admet-520	51	16	otherwise	otherwise	ADV
admet-520	51	17	stated	state	VERB
admet-520	51	18	.	.	PUNCT
admet-520	52	1	amicon	amicon	PROPN
admet-520	52	2	centrifugal	centrifugal	ADJ
admet-520	52	3	filter	filter	NOUN
admet-520	52	4	units	unit	NOUN
admet-520	52	5	(	(	PUNCT
admet-520	52	6	15	15	NUM
admet-520	52	7	ml	ml	NOUN
admet-520	52	8	)	)	PUNCT
admet-520	52	9	(	(	PUNCT
admet-520	52	10	merck	merck	PROPN
admet-520	52	11	millipore	millipore	PROPN
admet-520	52	12	,	,	PUNCT
admet-520	52	13	ireland	ireland	PROPN
admet-520	52	14	)	)	PUNCT
admet-520	52	15	and	and	CCONJ
admet-520	52	16	sequencing	sequence	VERB
admet-520	52	17	grade	grade	NOUN
admet-520	52	18	modified	modify	VERB
admet-520	52	19	trypsin	trypsin	NOUN
admet-520	52	20	(	(	PUNCT
admet-520	52	21	promega	promega	PROPN
admet-520	52	22	,	,	PUNCT
admet-520	52	23	madison	madison	PROPN
admet-520	52	24	,	,	PUNCT
admet-520	52	25	wi	wi	PROPN
admet-520	52	26	)	)	PUNCT
admet-520	52	27	were	be	AUX
admet-520	52	28	used	use	VERB
admet-520	52	29	for	for	ADP
admet-520	52	30	the	the	DET
admet-520	52	31	digestion	digestion	NOUN
admet-520	52	32	.	.	PUNCT
admet-520	53	1	standard	standard	ADJ
admet-520	53	2	peptides	peptide	NOUN
admet-520	53	3	p1	p1	NOUN
admet-520	53	4	-	-	PUNCT
admet-520	53	5	p6	p6	PROPN
admet-520	53	6	[	[	X
admet-520	53	7	24	24	NUM
admet-520	53	8	]	]	PUNCT
admet-520	53	9	synthesized	synthesize	VERB
admet-520	53	10	by	by	ADP
admet-520	53	11	biosynthesis	biosynthesis	PROPN
admet-520	53	12	inc	inc	PROPN
admet-520	53	13	.	.	PROPN
admet-520	53	14	(	(	PUNCT
admet-520	53	15	lewisville	lewisville	PROPN
admet-520	53	16	,	,	PUNCT
admet-520	53	17	tx	tx	PROPN
admet-520	53	18	)	)	PUNCT
admet-520	53	19	were	be	AUX
admet-520	53	20	used	use	VERB
admet-520	53	21	for	for	ADP
admet-520	53	22	the	the	DET
admet-520	53	23	preliminary	preliminary	ADJ
admet-520	53	24	experiments	experiment	NOUN
admet-520	53	25	to	to	PART
admet-520	53	26	establish	establish	VERB
admet-520	53	27	the	the	DET
admet-520	53	28	gradient	gradient	ADJ
admet-520	53	29	separation	separation	NOUN
admet-520	53	30	conditions	condition	NOUN
admet-520	53	31	at	at	ADP
admet-520	53	32	ph	ph	PROPN
admet-520	53	33	7.4	7.4	NUM
admet-520	53	34	.	.	PUNCT
admet-520	54	1	luna	luna	PROPN
admet-520	54	2	c18(2	c18(2	PROPN
admet-520	54	3	)	)	PUNCT
admet-520	54	4	,	,	PUNCT
admet-520	54	5	5	5	NUM
admet-520	54	6	µm	µm	NOUN
admet-520	54	7	(	(	PUNCT
admet-520	54	8	phenomenex	phenomenex	ADV
admet-520	54	9	,	,	PUNCT
admet-520	54	10	torrance	torrance	NOUN
admet-520	54	11	,	,	PUNCT
admet-520	54	12	ca	ca	NOUN
admet-520	54	13	)	)	PUNCT
admet-520	54	14	and	and	CCONJ
admet-520	54	15	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	54	16	,	,	PUNCT
admet-520	54	17	10	10	NUM
admet-520	54	18	µm	µm	PART
admet-520	54	19	(	(	PUNCT
admet-520	54	20	regis	regis	PROPN
admet-520	54	21	technologies	technologies	PROPN
admet-520	54	22	,	,	PUNCT
admet-520	54	23	grove	grove	PROPN
admet-520	54	24	,	,	PUNCT
admet-520	54	25	il	il	PROPN
admet-520	54	26	)	)	PUNCT
admet-520	54	27	columns	column	NOUN
admet-520	54	28	(	(	PUNCT
admet-520	54	29	1x100	1x100	NUM
admet-520	54	30	mm	mm	NOUN
admet-520	54	31	)	)	PUNCT
admet-520	54	32	were	be	AUX
admet-520	54	33	packed	pack	VERB
admet-520	54	34	in	in	ADP
admet-520	54	35	-	-	PUNCT
admet-520	54	36	house	house	NOUN
admet-520	54	37	.	.	PUNCT
admet-520	55	1	first	first	ADJ
admet-520	55	2	dimension	dimension	NOUN
admet-520	55	3	separation	separation	NOUN
admet-520	55	4	an	an	DET
admet-520	55	5	agilent	agilent	PROPN
admet-520	55	6	1100	1100	NUM
admet-520	55	7	series	series	PROPN
admet-520	55	8	hplc	hplc	NOUN
admet-520	55	9	system	system	NOUN
admet-520	55	10	fitted	fit	VERB
admet-520	55	11	with	with	ADP
admet-520	55	12	uv	uv	NOUN
admet-520	55	13	detector	detector	NOUN
admet-520	55	14	(	(	PUNCT
admet-520	55	15	214	214	NUM
admet-520	55	16	nm	nm	NOUN
admet-520	55	17	)	)	PUNCT
admet-520	55	18	,	,	PUNCT
admet-520	55	19	a	a	DET
admet-520	55	20	100	100	NUM
admet-520	55	21	µl	µl	ADP
admet-520	55	22	injection	injection	NOUN
admet-520	55	23	loop	loop	NOUN
admet-520	55	24	and	and	CCONJ
admet-520	55	25	operating	operate	VERB
admet-520	55	26	at	at	ADP
admet-520	55	27	a	a	DET
admet-520	55	28	150	150	NUM
admet-520	55	29	µl	µl	NOUN
admet-520	55	30	/	/	SYM
admet-520	55	31	min	min	NOUN
admet-520	55	32	flow	flow	NOUN
admet-520	55	33	rate	rate	NOUN
admet-520	55	34	was	be	AUX
admet-520	55	35	used	use	VERB
admet-520	55	36	for	for	ADP
admet-520	55	37	separations	separation	NOUN
admet-520	55	38	of	of	ADP
admet-520	55	39	standard	standard	ADJ
admet-520	55	40	peptide	peptide	NOUN
admet-520	55	41	mixtures	mixture	NOUN
admet-520	55	42	and	and	CCONJ
admet-520	55	43	the	the	DET
admet-520	55	44	complex	complex	ADJ
admet-520	55	45	digest	digest	NOUN
admet-520	55	46	.	.	PUNCT
admet-520	56	1	identical	identical	ADJ
admet-520	56	2	gradients	gradient	NOUN
admet-520	56	3	of	of	ADP
admet-520	56	4	1	1	NUM
admet-520	56	5	%	%	NOUN
admet-520	56	6	acetonitrile	acetonitrile	NOUN
admet-520	56	7	per	per	ADP
admet-520	56	8	minute	minute	NOUN
admet-520	56	9	were	be	AUX
admet-520	56	10	used	use	VERB
admet-520	56	11	for	for	ADP
admet-520	56	12	both	both	DET
admet-520	56	13	columns	column	NOUN
admet-520	56	14	.	.	PUNCT
admet-520	57	1	eluent	eluent	NOUN
admet-520	57	2	a	a	DET
admet-520	57	3	consisted	consisted	NOUN
admet-520	57	4	of	of	ADP
admet-520	57	5	20	20	NUM
admet-520	57	6	mm	mm	NOUN
admet-520	57	7	ammonium	ammonium	NOUN
admet-520	57	8	bicarbonate	bicarbonate	NOUN
admet-520	57	9	in	in	ADP
admet-520	57	10	water	water	NOUN
admet-520	57	11	.	.	PUNCT
admet-520	58	1	a	a	DET
admet-520	58	2	200	200	NUM
admet-520	58	3	mm	mm	NOUN
admet-520	58	4	ammonium	ammonium	NOUN
admet-520	58	5	bicarbonate	bicarbonate	NOUN
admet-520	58	6	stock	stock	NOUN
admet-520	58	7	solution	solution	NOUN
admet-520	58	8	was	be	AUX
admet-520	58	9	diluted	dilute	VERB
admet-520	58	10	10	10	NUM
admet-520	58	11	times	time	NOUN
admet-520	58	12	and	and	CCONJ
admet-520	58	13	the	the	DET
admet-520	58	14	ph	ph	NOUN
admet-520	58	15	was	be	AUX
admet-520	58	16	adjusted	adjust	VERB
admet-520	58	17	with	with	ADP
admet-520	58	18	formic	formic	ADJ
admet-520	58	19	acid	acid	NOUN
admet-520	58	20	to	to	ADP
admet-520	58	21	7.4	7.4	NUM
admet-520	58	22	.	.	PUNCT
admet-520	59	1	eluent	eluent	PROPN
admet-520	59	2	b	b	PROPN
admet-520	59	3	consisted	consist	VERB
admet-520	59	4	of	of	ADP
admet-520	59	5	20	20	NUM
admet-520	59	6	mm	mm	NOUN
admet-520	59	7	ammonium	ammonium	NOUN
admet-520	59	8	bicarbonate	bicarbonate	NOUN
admet-520	59	9	,	,	PUNCT
admet-520	59	10	ph	ph	NOUN
admet-520	59	11	7.4	7.4	NUM
admet-520	59	12	,	,	PUNCT
admet-520	59	13	in	in	ADP
admet-520	59	14	70/30	70/30	NUM
admet-520	59	15	acetonitrile	acetonitrile	ADJ
admet-520	59	16	/	/	SYM
admet-520	59	17	water	water	NOUN
admet-520	59	18	.	.	PUNCT
admet-520	60	1	the	the	DET
admet-520	60	2	gradient	gradient	PROPN
admet-520	60	3	program	program	NOUN
admet-520	60	4	included	include	VERB
admet-520	60	5	the	the	DET
admet-520	60	6	following	follow	VERB
admet-520	60	7	steps	step	NOUN
admet-520	60	8	:	:	PUNCT
admet-520	60	9	a	a	DET
admet-520	60	10	linear	linear	ADJ
admet-520	60	11	increase	increase	NOUN
admet-520	60	12	from	from	ADP
admet-520	60	13	0	0	NUM
admet-520	60	14	to	to	ADP
admet-520	60	15	71.4	71.4	NUM
admet-520	60	16	%	%	NOUN
admet-520	60	17	b	b	NOUN
admet-520	60	18	in	in	ADP
admet-520	60	19	50	50	NUM
admet-520	60	20	min	min	NOUN
admet-520	60	21	,	,	PUNCT
admet-520	60	22	10	10	NUM
admet-520	60	23	min	min	NOUN
admet-520	60	24	wash	wash	NOUN
admet-520	60	25	with	with	ADP
admet-520	60	26	90	90	NUM
admet-520	60	27	%	%	NOUN
admet-520	60	28	b	b	NOUN
admet-520	60	29	and	and	CCONJ
admet-520	60	30	30	30	NUM
admet-520	60	31	min	min	NOUN
admet-520	60	32	equilibration	equilibration	NOUN
admet-520	60	33	with	with	ADP
admet-520	60	34	100	100	NUM
admet-520	60	35	%	%	NOUN
admet-520	60	36	a.	a.	NOUN
admet-520	60	37	one	one	NUM
admet-520	60	38	-	-	PUNCT
admet-520	60	39	minute	minute	NOUN
admet-520	60	40	fractions	fraction	NOUN
admet-520	60	41	were	be	AUX
admet-520	60	42	collected	collect	VERB
admet-520	60	43	within	within	ADP
admet-520	60	44	the	the	DET
admet-520	60	45	expected	expect	VERB
admet-520	60	46	interval	interval	NOUN
admet-520	60	47	of	of	ADP
admet-520	60	48	peptide	peptide	ADJ
admet-520	60	49	elution	elution	NOUN
admet-520	60	50	.	.	PUNCT
admet-520	61	1	fractions	fraction	NOUN
admet-520	61	2	were	be	AUX
admet-520	61	3	lyophilized	lyophilize	VERB
admet-520	61	4	and	and	CCONJ
admet-520	61	5	re	re	VERB
admet-520	61	6	-	-	VERB
admet-520	61	7	suspended	suspend	VERB
admet-520	61	8	in	in	ADP
admet-520	61	9	30	30	NUM
admet-520	61	10	l	l	PROPN
admet-520	61	11	of	of	ADP
admet-520	61	12	0.2	0.2	NUM
admet-520	61	13	%	%	NOUN
admet-520	61	14	formic	formic	ADJ
admet-520	61	15	acid	acid	NOUN
admet-520	61	16	in	in	ADP
admet-520	61	17	water	water	NOUN
admet-520	61	18	and	and	CCONJ
admet-520	61	19	spiked	spike	VERB
admet-520	61	20	with	with	ADP
admet-520	61	21	~200	~200	ADJ
admet-520	61	22	fm	fm	PROPN
admet-520	61	23	of	of	ADP
admet-520	61	24	standard	standard	ADJ
admet-520	61	25	peptides	peptide	NOUN
admet-520	61	26	p1	p1	NOUN
admet-520	61	27	-	-	PUNCT
admet-520	61	28	p6	p6	NOUN
admet-520	61	29	for	for	ADP
admet-520	61	30	retention	retention	NOUN
admet-520	61	31	time	time	NOUN
admet-520	61	32	alignment	alignment	NOUN
admet-520	61	33	purposes	purpose	NOUN
admet-520	61	34	.	.	PUNCT
admet-520	62	1	one	one	NUM
admet-520	62	2	-	-	PUNCT
admet-520	62	3	third	third	NOUN
admet-520	62	4	of	of	ADP
admet-520	62	5	each	each	DET
admet-520	62	6	collected	collect	VERB
admet-520	62	7	fraction	fraction	NOUN
admet-520	62	8	(	(	PUNCT
admet-520	62	9	10	10	NUM
admet-520	62	10	µl	µl	NOUN
admet-520	62	11	)	)	PUNCT
admet-520	62	12	was	be	AUX
admet-520	62	13	injected	inject	VERB
admet-520	62	14	in	in	ADP
admet-520	62	15	the	the	DET
admet-520	62	16	second	second	ADJ
admet-520	62	17	dimension	dimension	NOUN
admet-520	62	18	.	.	PUNCT
admet-520	63	1	admet	admet	PROPN
admet-520	63	2	&	&	CCONJ
admet-520	63	3	dmpk	dmpk	PROPN
admet-520	63	4	6(2	6(2	NUM
admet-520	63	5	)	)	PUNCT
admet-520	63	6	(	(	PUNCT
admet-520	63	7	2018	2018	NUM
admet-520	63	8	)	)	PUNCT
admet-520	63	9	190	190	NUM
admet-520	63	10	-	-	SYM
admet-520	63	11	199	199	NUM
admet-520	63	12	peptide	peptide	NOUN
admet-520	63	13	retention	retention	NOUN
admet-520	63	14	time	time	NOUN
admet-520	63	15	prediction	prediction	NOUN
admet-520	63	16	for	for	ADP
admet-520	63	17	iam.pc	iam.pc	PROPN
admet-520	63	18	stationary	stationary	ADJ
admet-520	63	19	phases	phase	NOUN
admet-520	63	20	doi	doi	NOUN
admet-520	63	21	:	:	PUNCT
admet-520	63	22	10.5599	10.5599	NUM
admet-520	63	23	/	/	SYM
admet-520	63	24	admet.520	admet.520	ADJ
admet-520	63	25	193	193	NUM
admet-520	63	26	second	second	ADJ
admet-520	63	27	dimension	dimension	NOUN
admet-520	63	28	lc	lc	PROPN
admet-520	63	29	-	-	PUNCT
admet-520	63	30	ms	ms	PROPN
admet-520	63	31	/	/	SYM
admet-520	63	32	ms	ms	PROPN
admet-520	63	33	second	second	ADJ
admet-520	63	34	dimension	dimension	NOUN
admet-520	63	35	lc	lc	PROPN
admet-520	63	36	-	-	PUNCT
admet-520	63	37	ms	ms	PROPN
admet-520	63	38	/	/	PROPN
admet-520	63	39	ms	ms	NOUN
admet-520	63	40	was	be	AUX
admet-520	63	41	done	do	VERB
admet-520	63	42	using	use	VERB
admet-520	63	43	a	a	DET
admet-520	63	44	standard	standard	ADJ
admet-520	63	45	data	datum	NOUN
admet-520	63	46	-	-	PUNCT
admet-520	63	47	dependent	dependent	ADJ
admet-520	63	48	acquisition	acquisition	NOUN
admet-520	63	49	protocol	protocol	NOUN
admet-520	63	50	using	use	VERB
admet-520	63	51	a	a	DET
admet-520	63	52	2d	2d	NUM
admet-520	63	53	lc	lc	ADP
admet-520	63	54	ultra	ultra	ADJ
admet-520	63	55	system	system	NOUN
admet-520	63	56	(	(	PUNCT
admet-520	63	57	eksigent	eksigent	PROPN
admet-520	63	58	,	,	PUNCT
admet-520	63	59	dublin	dublin	PROPN
admet-520	63	60	,	,	PUNCT
admet-520	63	61	ca	ca	NOUN
admet-520	63	62	)	)	PUNCT
admet-520	63	63	and	and	CCONJ
admet-520	63	64	a	a	DET
admet-520	63	65	tripletof5600	tripletof5600	NUM
admet-520	63	66	mass	mass	NOUN
admet-520	63	67	spectrometer	spectrometer	NOUN
admet-520	63	68	(	(	PUNCT
admet-520	63	69	sciex	sciex	NOUN
admet-520	63	70	,	,	PUNCT
admet-520	63	71	concord	concord	PROPN
admet-520	63	72	,	,	PUNCT
admet-520	63	73	on	on	ADP
admet-520	63	74	)	)	PUNCT
admet-520	63	75	as	as	SCONJ
admet-520	63	76	described	describe	VERB
admet-520	63	77	[	[	X
admet-520	63	78	19	19	NUM
admet-520	63	79	]	]	PUNCT
admet-520	63	80	.	.	PUNCT
admet-520	64	1	lc	lc	NOUN
admet-520	64	2	settings	setting	NOUN
admet-520	64	3	featured	feature	VERB
admet-520	64	4	a	a	DET
admet-520	64	5	100	100	NUM
admet-520	64	6	µm	µm	NOUN
admet-520	64	7	x	x	SYM
admet-520	64	8	200	200	NUM
admet-520	64	9	mm	mm	PROPN
admet-520	64	10	analytical	analytical	ADJ
admet-520	64	11	column	column	NOUN
admet-520	64	12	packed	pack	VERB
admet-520	64	13	with	with	ADP
admet-520	64	14	3	3	NUM
admet-520	64	15	µm	µm	ADP
admet-520	64	16	luna	luna	PROPN
admet-520	64	17	c18(2	c18(2	PROPN
admet-520	64	18	)	)	PUNCT
admet-520	64	19	(	(	PUNCT
admet-520	64	20	phenomenex	phenomenex	ADV
admet-520	64	21	,	,	PUNCT
admet-520	64	22	torrance	torrance	NOUN
admet-520	64	23	,	,	PUNCT
admet-520	64	24	ca	ca	NOUN
admet-520	64	25	)	)	PUNCT
admet-520	64	26	and	and	CCONJ
admet-520	64	27	a	a	DET
admet-520	64	28	300	300	NUM
admet-520	64	29	µm	µm	NOUN
admet-520	64	30	x	x	SYM
admet-520	64	31	5	5	NUM
admet-520	64	32	mm	mm	PROPN
admet-520	64	33	pepmap	pepmap	NOUN
admet-520	64	34	100	100	NUM
admet-520	64	35	trap	trap	NOUN
admet-520	64	36	-	-	PUNCT
admet-520	64	37	column	column	NOUN
admet-520	64	38	(	(	PUNCT
admet-520	64	39	thermo	thermo	NOUN
admet-520	64	40	fisher	fisher	PROPN
admet-520	64	41	)	)	PUNCT
admet-520	64	42	.	.	PUNCT
admet-520	65	1	a	a	DET
admet-520	65	2	500	500	NUM
admet-520	65	3	nl	nl	PROPN
admet-520	65	4	/	/	SYM
admet-520	65	5	min	min	NOUN
admet-520	65	6	flow	flow	NOUN
admet-520	65	7	rate	rate	NOUN
admet-520	65	8	was	be	AUX
admet-520	65	9	used	use	VERB
admet-520	65	10	with	with	ADP
admet-520	65	11	~0.4	~0.4	NOUN
admet-520	65	12	%	%	NOUN
admet-520	65	13	acetonitrile	acetonitrile	NOUN
admet-520	65	14	per	per	ADP
admet-520	65	15	minute	minute	NOUN
admet-520	65	16	gradient	gradient	NOUN
admet-520	65	17	.	.	PUNCT
admet-520	66	1	both	both	DET
admet-520	66	2	buffers	buffer	NOUN
admet-520	66	3	a	a	DET
admet-520	66	4	(	(	PUNCT
admet-520	66	5	water	water	NOUN
admet-520	66	6	)	)	PUNCT
admet-520	66	7	and	and	CCONJ
admet-520	66	8	b	b	X
admet-520	66	9	(	(	PUNCT
admet-520	66	10	acetonitrile	acetonitrile	NOUN
admet-520	66	11	)	)	PUNCT
admet-520	66	12	contained	contain	VERB
admet-520	66	13	0.1	0.1	NUM
admet-520	66	14	%	%	NOUN
admet-520	66	15	formic	formic	ADJ
admet-520	66	16	acid	acid	NOUN
admet-520	66	17	.	.	PUNCT
admet-520	67	1	the	the	DET
admet-520	67	2	gradient	gradient	PROPN
admet-520	67	3	program	program	NOUN
admet-520	67	4	consisted	consist	VERB
admet-520	67	5	of	of	ADP
admet-520	67	6	the	the	DET
admet-520	67	7	following	follow	VERB
admet-520	67	8	steps	step	NOUN
admet-520	67	9	:	:	PUNCT
admet-520	67	10	a	a	DET
admet-520	67	11	linear	linear	ADJ
admet-520	67	12	increase	increase	NOUN
admet-520	67	13	from	from	ADP
admet-520	67	14	0.4	0.4	NUM
admet-520	67	15	to	to	PART
admet-520	67	16	31	31	NUM
admet-520	67	17	%	%	NOUN
admet-520	67	18	buffer	buffer	NOUN
admet-520	67	19	b	b	NOUN
admet-520	67	20	(	(	PUNCT
admet-520	67	21	acetonitrile	acetonitrile	NOUN
admet-520	67	22	)	)	PUNCT
admet-520	67	23	in	in	ADP
admet-520	67	24	77	77	NUM
admet-520	67	25	minutes	minute	NOUN
admet-520	67	26	,	,	PUNCT
admet-520	67	27	5	5	NUM
admet-520	67	28	minutes	minute	NOUN
admet-520	67	29	at	at	ADP
admet-520	67	30	80	80	NUM
admet-520	67	31	%	%	NOUN
admet-520	67	32	b	b	NOUN
admet-520	67	33	and	and	CCONJ
admet-520	67	34	then	then	ADV
admet-520	67	35	8	8	NUM
admet-520	67	36	minutes	minute	NOUN
admet-520	67	37	at	at	ADP
admet-520	67	38	0.4	0.4	NUM
admet-520	67	39	%	%	NOUN
admet-520	67	40	b	b	NOUN
admet-520	67	41	for	for	ADP
admet-520	67	42	column	column	NOUN
admet-520	67	43	equilibration	equilibration	NOUN
admet-520	67	44	(	(	PUNCT
admet-520	67	45	90	90	NUM
admet-520	67	46	min	min	NOUN
admet-520	67	47	total	total	ADJ
admet-520	67	48	analysis	analysis	NOUN
admet-520	67	49	time	time	NOUN
admet-520	67	50	)	)	PUNCT
admet-520	67	51	.	.	PUNCT
admet-520	68	1	data	datum	NOUN
admet-520	68	2	analysis	analysis	NOUN
admet-520	68	3	and	and	CCONJ
admet-520	68	4	retention	retention	NOUN
admet-520	68	5	time	time	NOUN
admet-520	68	6	assignment	assignment	NOUN
admet-520	68	7	x!tandem	x!tandem	PROPN
admet-520	68	8	’s	’s	PART
admet-520	68	9	search	search	NOUN
admet-520	68	10	algorithm	algorithm	NOUN
admet-520	68	11	was	be	AUX
admet-520	68	12	used	use	VERB
admet-520	68	13	with	with	ADP
admet-520	68	14	the	the	DET
admet-520	68	15	following	follow	VERB
admet-520	68	16	parameters	parameter	NOUN
admet-520	68	17	:	:	PUNCT
admet-520	68	18	20	20	NUM
admet-520	68	19	ppm	ppm	NOUN
admet-520	68	20	and	and	CCONJ
admet-520	68	21	50	50	NUM
admet-520	68	22	ppm	ppm	NOUN
admet-520	68	23	mass	mass	NOUN
admet-520	68	24	tolerance	tolerance	NOUN
admet-520	68	25	for	for	ADP
admet-520	68	26	parent	parent	NOUN
admet-520	68	27	and	and	CCONJ
admet-520	68	28	daughter	daughter	NOUN
admet-520	68	29	ions	ion	NOUN
admet-520	68	30	,	,	PUNCT
admet-520	68	31	respectively	respectively	ADV
admet-520	68	32	;	;	PUNCT
admet-520	68	33	constant	constant	ADJ
admet-520	68	34	modification	modification	NOUN
admet-520	68	35	of	of	ADP
admet-520	68	36	cys	cys	PROPN
admet-520	68	37	with	with	ADP
admet-520	68	38	iodoacetamide	iodoacetamide	NOUN
admet-520	68	39	.	.	PUNCT
admet-520	69	1	all	all	PRON
admet-520	69	2	identified	identify	VERB
admet-520	69	3	tryptic	tryptic	ADJ
admet-520	69	4	non	non	ADJ
admet-520	69	5	-	-	ADJ
admet-520	69	6	modified	modified	ADJ
admet-520	69	7	peptides	peptide	NOUN
admet-520	69	8	(	(	PUNCT
admet-520	69	9	log	log	NOUN
admet-520	69	10	(	(	PUNCT
admet-520	69	11	e	e	NOUN
admet-520	69	12	)	)	PUNCT
admet-520	69	13	<	<	X
admet-520	69	14	-1	-1	X
admet-520	69	15	)	)	PUNCT
admet-520	69	16	were	be	AUX
admet-520	69	17	additionally	additionally	ADV
admet-520	69	18	filtered	filter	VERB
admet-520	69	19	using	use	VERB
admet-520	69	20	retention	retention	NOUN
admet-520	69	21	time	time	NOUN
admet-520	69	22	prediction	prediction	NOUN
admet-520	69	23	in	in	ADP
admet-520	69	24	the	the	DET
admet-520	69	25	second	second	ADJ
admet-520	69	26	dimension	dimension	NOUN
admet-520	69	27	.	.	PUNCT
admet-520	70	1	retention	retention	NOUN
admet-520	70	2	times	time	NOUN
admet-520	70	3	in	in	ADP
admet-520	70	4	the	the	DET
admet-520	70	5	first	first	ADJ
admet-520	70	6	dimension	dimension	NOUN
admet-520	70	7	were	be	AUX
admet-520	70	8	assigned	assign	VERB
admet-520	70	9	as	as	ADP
admet-520	70	10	equal	equal	ADJ
admet-520	70	11	to	to	ADP
admet-520	70	12	the	the	DET
admet-520	70	13	fraction	fraction	NOUN
admet-520	70	14	number	number	NOUN
admet-520	70	15	in	in	ADP
admet-520	70	16	which	which	PRON
admet-520	70	17	the	the	DET
admet-520	70	18	peptide	peptide	NOUN
admet-520	70	19	was	be	AUX
admet-520	70	20	found	find	VERB
admet-520	70	21	.	.	PUNCT
admet-520	71	1	when	when	SCONJ
admet-520	71	2	the	the	DET
admet-520	71	3	peptide	peptide	NOUN
admet-520	71	4	signal	signal	NOUN
admet-520	71	5	was	be	AUX
admet-520	71	6	distributed	distribute	VERB
admet-520	71	7	between	between	ADP
admet-520	71	8	two	two	NUM
admet-520	71	9	or	or	CCONJ
admet-520	71	10	more	more	ADJ
admet-520	71	11	fractions	fraction	NOUN
admet-520	71	12	,	,	PUNCT
admet-520	71	13	the	the	DET
admet-520	71	14	intensity	intensity	NOUN
admet-520	71	15	weighted	weight	VERB
admet-520	71	16	average	average	ADJ
admet-520	71	17	fraction	fraction	NOUN
admet-520	71	18	number	number	NOUN
admet-520	71	19	was	be	AUX
admet-520	71	20	used	use	VERB
admet-520	71	21	.	.	PUNCT
admet-520	72	1	results	result	NOUN
admet-520	72	2	and	and	CCONJ
admet-520	72	3	discussion	discussion	NOUN
admet-520	72	4	selection	selection	NOUN
admet-520	72	5	of	of	ADP
admet-520	72	6	peptide	peptide	NOUN
admet-520	72	7	reversed	reverse	VERB
admet-520	72	8	-	-	PUNCT
admet-520	72	9	phase	phase	NOUN
admet-520	72	10	separation	separation	NOUN
admet-520	72	11	conditions	condition	NOUN
admet-520	72	12	on	on	ADP
admet-520	72	13	c18	c18	NOUN
admet-520	72	14	and	and	CCONJ
admet-520	72	15	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	72	16	phases	phase	NOUN
admet-520	72	17	at	at	ADP
admet-520	72	18	ph	ph	PROPN
admet-520	72	19	7.4	7.4	NUM
admet-520	72	20	.	.	PUNCT
admet-520	73	1	the	the	DET
admet-520	73	2	majority	majority	NOUN
admet-520	73	3	of	of	ADP
admet-520	73	4	peptide	peptide	ADJ
admet-520	73	5	retention	retention	NOUN
admet-520	73	6	time	time	NOUN
admet-520	73	7	modelling	model	VERB
admet-520	73	8	studies	study	NOUN
admet-520	73	9	have	have	AUX
admet-520	73	10	been	be	AUX
admet-520	73	11	performed	perform	VERB
admet-520	73	12	using	use	VERB
admet-520	73	13	acidic	acidic	ADJ
admet-520	73	14	eluent	eluent	NOUN
admet-520	73	15	conditions	condition	NOUN
admet-520	73	16	(	(	PUNCT
admet-520	73	17	usually	usually	ADV
admet-520	73	18	formic	formic	ADJ
admet-520	73	19	acid	acid	NOUN
admet-520	73	20	)	)	PUNCT
admet-520	73	21	–	–	PUNCT
admet-520	73	22	a	a	DET
admet-520	73	23	standard	standard	ADJ
admet-520	73	24	setting	setting	NOUN
admet-520	73	25	in	in	ADP
admet-520	73	26	proteomic	proteomic	ADJ
admet-520	73	27	lc	lc	PROPN
admet-520	73	28	-	-	PUNCT
admet-520	73	29	ms	ms	PROPN
admet-520	73	30	.	.	PROPN
admet-520	74	1	however	however	ADV
admet-520	74	2	,	,	PUNCT
admet-520	74	3	biomimetic	biomimetic	ADJ
admet-520	74	4	separations	separation	NOUN
admet-520	74	5	usually	usually	ADV
admet-520	74	6	use	use	VERB
admet-520	74	7	physiological	physiological	ADJ
admet-520	74	8	ph	ph	NOUN
admet-520	74	9	to	to	PART
admet-520	74	10	maximize	maximize	VERB
admet-520	74	11	the	the	DET
admet-520	74	12	similarity	similarity	NOUN
admet-520	74	13	between	between	ADP
admet-520	74	14	biological	biological	ADJ
admet-520	74	15	systems	system	NOUN
admet-520	74	16	and	and	CCONJ
admet-520	74	17	the	the	DET
admet-520	74	18	artificial	artificial	ADJ
admet-520	74	19	biphasic	biphasic	ADJ
admet-520	74	20	separation	separation	NOUN
admet-520	74	21	environment	environment	NOUN
admet-520	74	22	.	.	PUNCT
admet-520	75	1	we	we	PRON
admet-520	75	2	decided	decide	VERB
admet-520	75	3	to	to	PART
admet-520	75	4	employ	employ	VERB
admet-520	75	5	ammonium	ammonium	NOUN
admet-520	75	6	bicarbonate	bicarbonate	NOUN
admet-520	75	7	–	–	PUNCT
admet-520	75	8	based	base	VERB
admet-520	75	9	buffer	buffer	NOUN
admet-520	75	10	at	at	ADP
admet-520	75	11	ph	ph	PROPN
admet-520	75	12	7.4	7.4	NUM
admet-520	75	13	and	and	CCONJ
admet-520	75	14	performed	perform	VERB
admet-520	75	15	separations	separation	NOUN
admet-520	75	16	on	on	ADP
admet-520	75	17	both	both	CCONJ
admet-520	75	18	the	the	DET
admet-520	75	19	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	75	20	phase	phase	NOUN
admet-520	75	21	and	and	CCONJ
admet-520	75	22	a	a	DET
admet-520	75	23	standard	standard	ADJ
admet-520	75	24	c18	c18	NOUN
admet-520	75	25	phase	phase	NOUN
admet-520	75	26	for	for	ADP
admet-520	75	27	comparison	comparison	NOUN
admet-520	75	28	.	.	PUNCT
admet-520	76	1	figure	figure	NOUN
admet-520	76	2	2	2	NUM
admet-520	76	3	(	(	PUNCT
admet-520	76	4	a	a	DET
admet-520	76	5	,	,	PUNCT
admet-520	76	6	b	b	NOUN
admet-520	76	7	)	)	PUNCT
admet-520	76	8	shows	show	VERB
admet-520	76	9	the	the	DET
admet-520	76	10	separation	separation	NOUN
admet-520	76	11	of	of	ADP
admet-520	76	12	a	a	DET
admet-520	76	13	standard	standard	ADJ
admet-520	76	14	mixture	mixture	NOUN
admet-520	76	15	of	of	ADP
admet-520	76	16	6	6	NUM
admet-520	76	17	peptides	peptide	NOUN
admet-520	76	18	on	on	ADP
admet-520	76	19	these	these	DET
admet-520	76	20	two	two	NUM
admet-520	76	21	columns	column	NOUN
admet-520	76	22	.	.	PUNCT
admet-520	77	1	the	the	DET
admet-520	77	2	p1p6	p1p6	NOUN
admet-520	77	3	peptide	peptide	NOUN
admet-520	77	4	mixture	mixture	NOUN
admet-520	77	5	was	be	AUX
admet-520	77	6	designed	design	VERB
admet-520	77	7	to	to	PART
admet-520	77	8	cover	cover	VERB
admet-520	77	9	the	the	DET
admet-520	77	10	entire	entire	ADJ
admet-520	77	11	hydrophobicity	hydrophobicity	NOUN
admet-520	77	12	range	range	NOUN
admet-520	77	13	for	for	ADP
admet-520	77	14	tryptic	tryptic	ADJ
admet-520	77	15	peptides	peptide	NOUN
admet-520	77	16	:	:	PUNCT
admet-520	77	17	i.e.	i.e.	X
admet-520	77	18	the	the	DET
admet-520	77	19	elution	elution	NOUN
admet-520	77	20	window	window	NOUN
admet-520	77	21	of	of	ADP
admet-520	77	22	the	the	DET
admet-520	77	23	reversed	reverse	VERB
admet-520	77	24	-	-	PUNCT
admet-520	77	25	phase	phase	NOUN
admet-520	77	26	separations	separation	NOUN
admet-520	77	27	.	.	PUNCT
admet-520	78	1	at	at	ADP
admet-520	78	2	acidic	acidic	ADJ
admet-520	78	3	eluent	eluent	NOUN
admet-520	78	4	conditions	condition	NOUN
admet-520	78	5	(	(	PUNCT
admet-520	78	6	0.1	0.1	NUM
admet-520	78	7	%	%	NOUN
admet-520	78	8	trifluoroacetic	trifluoroacetic	ADJ
admet-520	78	9	acid	acid	NOUN
admet-520	78	10	)	)	PUNCT
admet-520	78	11	they	they	PRON
admet-520	78	12	elute	elute	VERB
admet-520	78	13	between	between	ADP
admet-520	78	14	4	4	NUM
admet-520	78	15	(	(	PUNCT
admet-520	78	16	p1	p1	NOUN
admet-520	78	17	)	)	PUNCT
admet-520	78	18	and	and	CCONJ
admet-520	78	19	29.6	29.6	NUM
admet-520	78	20	(	(	PUNCT
admet-520	78	21	p6	p6	PROPN
admet-520	78	22	)	)	PUNCT
admet-520	78	23	%	%	NOUN
admet-520	78	24	acetonitrile	acetonitrile	NOUN
admet-520	78	25	(	(	PUNCT
admet-520	78	26	min	min	NOUN
admet-520	78	27	)	)	PUNCT
admet-520	78	28	[	[	X
admet-520	78	29	24	24	NUM
admet-520	78	30	]	]	PUNCT
admet-520	78	31	–	–	PUNCT
admet-520	78	32	very	very	ADV
admet-520	78	33	similar	similar	ADJ
admet-520	78	34	to	to	ADP
admet-520	78	35	the	the	DET
admet-520	78	36	~26	~26	NUM
admet-520	78	37	%	%	NOUN
admet-520	78	38	acetonitrile	acetonitrile	NOUN
admet-520	78	39	(	(	PUNCT
admet-520	78	40	min	min	NOUN
admet-520	78	41	)	)	PUNCT
admet-520	78	42	retention	retention	NOUN
admet-520	78	43	window	window	NOUN
admet-520	78	44	on	on	ADP
admet-520	78	45	c18	c18	NOUN
admet-520	78	46	phase	phase	NOUN
admet-520	78	47	at	at	ADP
admet-520	78	48	ph	ph	PROPN
admet-520	78	49	7.4	7.4	NUM
admet-520	78	50	(	(	PUNCT
admet-520	78	51	figure	figure	NOUN
admet-520	78	52	2a	2a	NUM
admet-520	78	53	)	)	PUNCT
admet-520	78	54	.	.	PUNCT
admet-520	79	1	peptide	peptide	ADJ
admet-520	79	2	retention	retention	NOUN
admet-520	79	3	on	on	ADP
admet-520	79	4	the	the	DET
admet-520	79	5	iam.pc	iam.pc	PROPN
admet-520	79	6	is	be	AUX
admet-520	79	7	significantly	significantly	ADV
admet-520	79	8	lower	low	ADJ
admet-520	79	9	(	(	PUNCT
admet-520	79	10	figure	figure	NOUN
admet-520	79	11	2b	2b	NOUN
admet-520	79	12	)	)	PUNCT
admet-520	79	13	.	.	PUNCT
admet-520	80	1	peptides	peptide	NOUN
admet-520	80	2	p1	p1	PROPN
admet-520	80	3	-	-	PUNCT
admet-520	80	4	p3	p3	PROPN
admet-520	80	5	are	be	AUX
admet-520	80	6	not	not	PART
admet-520	80	7	retained	retain	VERB
admet-520	80	8	,	,	PUNCT
admet-520	80	9	while	while	SCONJ
admet-520	80	10	the	the	DET
admet-520	80	11	retention	retention	NOUN
admet-520	80	12	time	time	NOUN
admet-520	80	13	decrease	decrease	NOUN
admet-520	80	14	for	for	ADP
admet-520	80	15	p4	p4	ADJ
admet-520	80	16	-	-	PUNCT
admet-520	80	17	p6	p6	NOUN
admet-520	80	18	was	be	AUX
admet-520	80	19	~16.7	~16.7	ADV
admet-520	80	20	min	min	NOUN
admet-520	80	21	(	(	PUNCT
admet-520	80	22	%	%	NOUN
admet-520	80	23	acetonitrile	acetonitrile	NOUN
admet-520	80	24	)	)	PUNCT
admet-520	80	25	on	on	ADP
admet-520	80	26	average	average	ADJ
admet-520	80	27	compared	compare	VERB
admet-520	80	28	to	to	ADP
admet-520	80	29	c18	c18	NOUN
admet-520	80	30	.	.	PUNCT
admet-520	81	1	a	a	DET
admet-520	81	2	significant	significant	ADJ
admet-520	81	3	decrease	decrease	NOUN
admet-520	81	4	in	in	ADP
admet-520	81	5	separation	separation	NOUN
admet-520	81	6	efficiency	efficiency	NOUN
admet-520	81	7	for	for	ADP
admet-520	81	8	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	81	9	was	be	AUX
admet-520	81	10	also	also	ADV
admet-520	81	11	obvious	obvious	ADJ
admet-520	81	12	and	and	CCONJ
admet-520	81	13	likely	likely	ADJ
admet-520	81	14	due	due	ADP
admet-520	81	15	to	to	ADP
admet-520	81	16	the	the	DET
admet-520	81	17	introduction	introduction	NOUN
admet-520	81	18	of	of	ADP
admet-520	81	19	mixed	mixed	ADJ
admet-520	81	20	-	-	PUNCT
admet-520	81	21	mode	mode	NOUN
admet-520	81	22	interactions	interaction	NOUN
admet-520	81	23	on	on	ADP
admet-520	81	24	the	the	DET
admet-520	81	25	phosphatidylcholine	phosphatidylcholine	NOUN
admet-520	81	26	phase	phase	NOUN
admet-520	81	27	and	and	CCONJ
admet-520	81	28	larger	large	ADJ
admet-520	81	29	particle	particle	NOUN
admet-520	81	30	size	size	NOUN
admet-520	81	31	.	.	PUNCT
admet-520	82	1	most	most	ADJ
admet-520	82	2	tryptic	tryptic	ADJ
admet-520	82	3	peptides	peptide	NOUN
admet-520	82	4	are	be	AUX
admet-520	82	5	expected	expect	VERB
admet-520	82	6	to	to	PART
admet-520	82	7	elute	elute	VERB
admet-520	82	8	in	in	ADP
admet-520	82	9	the	the	DET
admet-520	82	10	range	range	NOUN
admet-520	82	11	between	between	ADP
admet-520	82	12	5	5	NUM
admet-520	82	13	and	and	CCONJ
admet-520	82	14	45	45	NUM
admet-520	82	15	min	min	NOUN
admet-520	82	16	from	from	ADP
admet-520	82	17	the	the	DET
admet-520	82	18	luna	luna	PROPN
admet-520	82	19	c18(2	c18(2	PROPN
admet-520	82	20	)	)	PUNCT
admet-520	82	21	column	column	NOUN
admet-520	82	22	under	under	ADP
admet-520	82	23	the	the	DET
admet-520	82	24	chromatographic	chromatographic	ADJ
admet-520	82	25	conditions	condition	NOUN
admet-520	82	26	used	use	VERB
admet-520	82	27	.	.	PUNCT
admet-520	83	1	based	base	VERB
admet-520	83	2	on	on	ADP
admet-520	83	3	preliminary	preliminary	ADJ
admet-520	83	4	experiments	experiment	NOUN
admet-520	83	5	with	with	ADP
admet-520	83	6	standard	standard	ADJ
admet-520	83	7	peptides	peptide	NOUN
admet-520	83	8	,	,	PUNCT
admet-520	83	9	the	the	DET
admet-520	83	10	elution	elution	NOUN
admet-520	83	11	window	window	NOUN
admet-520	83	12	for	for	ADP
admet-520	83	13	iam.pc	iam.pc	PROPN
admet-520	83	14	was	be	AUX
admet-520	83	15	expected	expect	VERB
admet-520	83	16	to	to	PART
admet-520	83	17	be	be	AUX
admet-520	83	18	smaller	small	ADJ
admet-520	83	19	.	.	PUNCT
admet-520	84	1	noting	note	VERB
admet-520	84	2	this	this	PRON
admet-520	84	3	we	we	PRON
admet-520	84	4	performed	perform	VERB
admet-520	84	5	separations	separation	NOUN
admet-520	84	6	of	of	ADP
admet-520	84	7	complex	complex	ADJ
admet-520	84	8	s.	s.	PROPN
admet-520	84	9	cerevisiae	cerevisiae	PROPN
admet-520	84	10	digests	digest	VERB
admet-520	84	11	(	(	PUNCT
admet-520	84	12	~150	~150	NOUN
admet-520	84	13	µg	µg	NOUN
admet-520	84	14	,	,	PUNCT
admet-520	84	15	figure	figure	VERB
admet-520	84	16	2(c	2(c	NUM
admet-520	84	17	,	,	PUNCT
admet-520	84	18	d	d	NOUN
admet-520	84	19	)	)	PUNCT
admet-520	84	20	)	)	PUNCT
admet-520	84	21	and	and	CCONJ
admet-520	84	22	collected	collect	VERB
admet-520	84	23	fractions	fraction	NOUN
admet-520	84	24	up	up	ADP
admet-520	84	25	to	to	PART
admet-520	84	26	45	45	NUM
admet-520	84	27	min	min	NOUN
admet-520	84	28	for	for	ADP
admet-520	84	29	each	each	DET
admet-520	84	30	run	run	NOUN
admet-520	84	31	.	.	PUNCT
admet-520	85	1	as	as	SCONJ
admet-520	85	2	expected	expect	VERB
admet-520	85	3	,	,	PUNCT
admet-520	85	4	both	both	DET
admet-520	85	5	chromatograms	chromatogram	NOUN
admet-520	85	6	showed	show	VERB
admet-520	85	7	no	no	DET
admet-520	85	8	well	well	ADV
admet-520	85	9	-	-	PUNCT
admet-520	85	10	resolved	resolve	VERB
admet-520	85	11	chromatographic	chromatographic	ADJ
admet-520	85	12	peaks	peak	NOUN
admet-520	85	13	due	due	ADJ
admet-520	85	14	to	to	ADP
admet-520	85	15	the	the	DET
admet-520	85	16	extremely	extremely	ADV
admet-520	85	17	high	high	ADJ
admet-520	85	18	complexity	complexity	NOUN
admet-520	85	19	of	of	ADP
admet-520	85	20	the	the	DET
admet-520	85	21	mixture	mixture	NOUN
admet-520	85	22	.	.	PUNCT
admet-520	86	1	at	at	ADP
admet-520	86	2	the	the	DET
admet-520	86	3	same	same	ADJ
admet-520	86	4	time	time	NOUN
admet-520	86	5	,	,	PUNCT
admet-520	86	6	the	the	DET
admet-520	86	7	overall	overall	ADJ
admet-520	86	8	retention	retention	NOUN
admet-520	86	9	profiles	profile	NOUN
admet-520	86	10	of	of	ADP
admet-520	86	11	tryptic	tryptic	ADJ
admet-520	86	12	peptides	peptide	NOUN
admet-520	86	13	in	in	ADP
admet-520	86	14	these	these	DET
admet-520	86	15	two	two	NUM
admet-520	86	16	systems	system	NOUN
admet-520	86	17	were	be	AUX
admet-520	86	18	quite	quite	ADV
admet-520	86	19	different	different	ADJ
admet-520	86	20	.	.	PUNCT
admet-520	87	1	the	the	DET
admet-520	87	2	majority	majority	NOUN
admet-520	87	3	of	of	ADP
admet-520	87	4	peptides	peptide	NOUN
admet-520	87	5	were	be	AUX
admet-520	87	6	retained	retain	VERB
admet-520	87	7	on	on	ADP
admet-520	87	8	the	the	DET
admet-520	87	9	c18	c18	NOUN
admet-520	87	10	column	column	NOUN
admet-520	87	11	and	and	CCONJ
admet-520	87	12	eluted	elute	VERB
admet-520	87	13	as	as	ADP
admet-520	87	14	a	a	DET
admet-520	87	15	typical	typical	ADJ
admet-520	87	16	bell	bell	NOUN
admet-520	87	17	-	-	PUNCT
admet-520	87	18	shaped	shape	VERB
admet-520	87	19	profile	profile	NOUN
admet-520	87	20	within	within	ADP
admet-520	87	21	a	a	DET
admet-520	87	22	5	5	NUM
admet-520	87	23	-	-	SYM
admet-520	87	24	40	40	NUM
admet-520	87	25	min	min	NOUN
admet-520	87	26	window	window	NOUN
admet-520	87	27	(	(	PUNCT
admet-520	87	28	figure	figure	NOUN
admet-520	87	29	2c	2c	NUM
admet-520	87	30	)	)	PUNCT
admet-520	87	31	.	.	PUNCT
admet-520	88	1	the	the	DET
admet-520	88	2	separation	separation	NOUN
admet-520	88	3	on	on	ADP
admet-520	88	4	oleg	oleg	PROPN
admet-520	88	5	krokhin	krokhin	PROPN
admet-520	88	6	et	et	PROPN
admet-520	88	7	al	al	PROPN
admet-520	88	8	.	.	PROPN
admet-520	88	9	admet	admet	PROPN
admet-520	88	10	&	&	CCONJ
admet-520	88	11	dmpk	dmpk	PROPN
admet-520	88	12	6(2	6(2	NUM
admet-520	88	13	)	)	PUNCT
admet-520	88	14	(	(	PUNCT
admet-520	88	15	2018	2018	NUM
admet-520	88	16	)	)	PUNCT
admet-520	88	17	190	190	NUM
admet-520	88	18	-	-	SYM
admet-520	88	19	199	199	NUM
admet-520	88	20	194	194	NUM
admet-520	88	21	the	the	DET
admet-520	88	22	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	88	23	phase	phase	NOUN
admet-520	88	24	exhibited	exhibit	VERB
admet-520	88	25	a	a	DET
admet-520	88	26	significant	significant	ADJ
admet-520	88	27	“	"	PUNCT
admet-520	88	28	break	break	NOUN
admet-520	88	29	-	-	PUNCT
admet-520	88	30	through	through	NOUN
admet-520	88	31	”	"	PUNCT
admet-520	88	32	–	–	PUNCT
admet-520	88	33	a	a	DET
admet-520	88	34	very	very	ADV
admet-520	88	35	high	high	ADJ
admet-520	88	36	peak	peak	NOUN
admet-520	88	37	at	at	ADP
admet-520	88	38	the	the	DET
admet-520	88	39	beginning	beginning	NOUN
admet-520	88	40	of	of	ADP
admet-520	88	41	the	the	DET
admet-520	88	42	chromatogram	chromatogram	NOUN
admet-520	88	43	containing	contain	VERB
admet-520	88	44	peptides	peptide	NOUN
admet-520	88	45	,	,	PUNCT
admet-520	88	46	which	which	PRON
admet-520	88	47	were	be	AUX
admet-520	88	48	not	not	PART
admet-520	88	49	retained	retain	VERB
admet-520	88	50	under	under	ADP
admet-520	88	51	the	the	DET
admet-520	88	52	starting	start	VERB
admet-520	88	53	gradient	gradient	NOUN
admet-520	88	54	conditions	condition	NOUN
admet-520	88	55	–	–	PUNCT
admet-520	88	56	similar	similar	ADJ
admet-520	88	57	to	to	ADP
admet-520	88	58	p1	p1	NOUN
admet-520	88	59	-	-	PUNCT
admet-520	88	60	p3	p3	PROPN
admet-520	88	61	in	in	ADP
admet-520	88	62	figure	figure	NOUN
admet-520	88	63	1b	1b	NUM
admet-520	88	64	.	.	PUNCT
admet-520	89	1	figure	figure	NOUN
admet-520	89	2	2	2	NUM
admet-520	89	3	.	.	PUNCT
admet-520	89	4	separation	separation	NOUN
admet-520	89	5	of	of	ADP
admet-520	89	6	standard	standard	ADJ
admet-520	89	7	peptides	peptide	NOUN
admet-520	89	8	and	and	CCONJ
admet-520	89	9	s.	s.	PROPN
admet-520	89	10	cerevisiae	cerevisiae	PROPN
admet-520	89	11	digest	digest	PROPN
admet-520	89	12	using	use	VERB
admet-520	89	13	luna	luna	PROPN
admet-520	89	14	c18(2	c18(2	PROPN
admet-520	89	15	)	)	PUNCT
admet-520	90	1	and	and	CCONJ
admet-520	90	2	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	90	3	columns	column	NOUN
admet-520	90	4	in	in	ADP
admet-520	90	5	the	the	DET
admet-520	90	6	reversed	reverse	VERB
admet-520	90	7	-	-	PUNCT
admet-520	90	8	phase	phase	NOUN
admet-520	90	9	separation	separation	NOUN
admet-520	90	10	mode	mode	NOUN
admet-520	90	11	.	.	PUNCT
admet-520	91	1	a	a	DET
admet-520	91	2	and	and	CCONJ
admet-520	91	3	b	b	NOUN
admet-520	91	4	–	–	PUNCT
admet-520	91	5	separation	separation	NOUN
admet-520	91	6	of	of	ADP
admet-520	91	7	standard	standard	ADJ
admet-520	91	8	peptides	peptide	NOUN
admet-520	91	9	p1	p1	NOUN
admet-520	91	10	-	-	PUNCT
admet-520	91	11	p6	p6	PROPN
admet-520	91	12	(	(	PUNCT
admet-520	91	13	lggggggdgsr	lggggggdgsr	PROPN
admet-520	91	14	,	,	PUNCT
admet-520	91	15	lggggggdfr	lggggggdfr	NOUN
admet-520	91	16	,	,	PUNCT
admet-520	91	17	llggggdfr	llggggdfr	ADJ
admet-520	91	18	,	,	PUNCT
admet-520	91	19	lllggdfr	lllggdfr	NOUN
admet-520	91	20	,	,	PUNCT
admet-520	91	21	lllldfr	lllldfr	NOUN
admet-520	91	22	,	,	PUNCT
admet-520	91	23	llllldfr	llllldfr	NOUN
admet-520	91	24	,	,	PUNCT
admet-520	91	25	[	[	X
admet-520	91	26	24	24	NUM
admet-520	91	27	]	]	PUNCT
admet-520	91	28	injection	injection	NOUN
admet-520	91	29	of	of	ADP
admet-520	91	30	~1	~1	NOUN
admet-520	91	31	µg	µg	ADV
admet-520	91	32	of	of	ADP
admet-520	91	33	each	each	DET
admet-520	91	34	peptide	peptide	NOUN
admet-520	91	35	)	)	PUNCT
admet-520	91	36	on	on	ADP
admet-520	91	37	luna	luna	PROPN
admet-520	91	38	c18(2	c18(2	PROPN
admet-520	91	39	)	)	PUNCT
admet-520	91	40	and	and	CCONJ
admet-520	91	41	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	91	42	,	,	PUNCT
admet-520	91	43	respectively	respectively	ADV
admet-520	91	44	;	;	PUNCT
admet-520	91	45	c	c	PROPN
admet-520	91	46	and	and	CCONJ
admet-520	91	47	d	d	PROPN
admet-520	91	48	–	–	PUNCT
admet-520	91	49	separation	separation	NOUN
admet-520	91	50	of	of	ADP
admet-520	91	51	~150	~150	NOUN
admet-520	91	52	µg	µg	ADV
admet-520	91	53	of	of	ADP
admet-520	91	54	s.	s.	PROPN
admet-520	91	55	cerevisiae	cerevisiae	PROPN
admet-520	91	56	digests	digest	NOUN
admet-520	91	57	.	.	PUNCT
admet-520	92	1	all	all	DET
admet-520	92	2	chromatograms	chromatogram	NOUN
admet-520	92	3	have	have	AUX
admet-520	92	4	been	be	AUX
admet-520	92	5	obtained	obtain	VERB
admet-520	92	6	using	use	VERB
admet-520	92	7	identical	identical	ADJ
admet-520	92	8	separation	separation	NOUN
admet-520	92	9	conditions	condition	NOUN
admet-520	92	10	with	with	ADP
admet-520	92	11	a	a	DET
admet-520	92	12	1	1	NUM
admet-520	92	13	%	%	NOUN
admet-520	92	14	acetonitrile	acetonitrile	NOUN
admet-520	92	15	per	per	ADP
admet-520	92	16	minute	minute	NOUN
admet-520	92	17	gradient	gradient	NOUN
admet-520	92	18	at	at	ADP
admet-520	92	19	ph	ph	PROPN
admet-520	92	20	7.4	7.4	NUM
admet-520	92	21	.	.	PUNCT
admet-520	93	1	identification	identification	NOUN
admet-520	93	2	outputs	output	NOUN
admet-520	93	3	for	for	ADP
admet-520	93	4	both	both	DET
admet-520	93	5	2d	2d	PROPN
admet-520	93	6	lc	lc	PROPN
admet-520	93	7	-	-	PUNCT
admet-520	93	8	ms	ms	PROPN
admet-520	93	9	/	/	SYM
admet-520	93	10	ms	ms	PROPN
admet-520	93	11	runs	run	VERB
admet-520	93	12	identification	identification	NOUN
admet-520	93	13	outputs	output	NOUN
admet-520	93	14	for	for	ADP
admet-520	93	15	both	both	DET
admet-520	93	16	2d	2d	PROPN
admet-520	93	17	lc	lc	PROPN
admet-520	93	18	-	-	PUNCT
admet-520	93	19	ms	ms	PROPN
admet-520	93	20	/	/	SYM
admet-520	93	21	ms	ms	PROPN
admet-520	93	22	runs	run	NOUN
admet-520	93	23	are	be	AUX
admet-520	93	24	shown	show	VERB
admet-520	93	25	in	in	ADP
admet-520	93	26	table	table	NOUN
admet-520	93	27	1	1	NUM
admet-520	93	28	,	,	PUNCT
admet-520	93	29	indicating	indicate	VERB
admet-520	93	30	significantly	significantly	ADV
admet-520	93	31	higher	high	ADJ
admet-520	93	32	redundancy	redundancy	NOUN
admet-520	93	33	in	in	ADP
admet-520	93	34	identification	identification	NOUN
admet-520	93	35	for	for	ADP
admet-520	93	36	the	the	DET
admet-520	93	37	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	93	38	run	run	NOUN
admet-520	93	39	.	.	PUNCT
admet-520	94	1	due	due	ADP
admet-520	94	2	to	to	ADP
admet-520	94	3	the	the	DET
admet-520	94	4	lower	low	ADJ
admet-520	94	5	separation	separation	NOUN
admet-520	94	6	efficiency	efficiency	NOUN
admet-520	94	7	in	in	ADP
admet-520	94	8	the	the	DET
admet-520	94	9	first	first	ADJ
admet-520	94	10	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	94	11	dimension	dimension	NOUN
admet-520	94	12	,	,	PUNCT
admet-520	94	13	individual	individual	ADJ
admet-520	94	14	peptides	peptide	NOUN
admet-520	94	15	were	be	AUX
admet-520	94	16	distributed	distribute	VERB
admet-520	94	17	through	through	ADP
admet-520	94	18	a	a	DET
admet-520	94	19	larger	large	ADJ
admet-520	94	20	number	number	NOUN
admet-520	94	21	of	of	ADP
admet-520	94	22	fractions	fraction	NOUN
admet-520	94	23	.	.	PUNCT
admet-520	95	1	this	this	PRON
admet-520	95	2	led	lead	VERB
admet-520	95	3	to	to	ADP
admet-520	95	4	an	an	DET
admet-520	95	5	acquisition	acquisition	NOUN
admet-520	95	6	of	of	ADP
admet-520	95	7	a	a	DET
admet-520	95	8	larger	large	ADJ
admet-520	95	9	number	number	NOUN
admet-520	95	10	of	of	ADP
admet-520	95	11	ms	ms	PROPN
admet-520	95	12	/	/	SYM
admet-520	95	13	ms	ms	PROPN
admet-520	95	14	spectra	spectra	PROPN
admet-520	95	15	,	,	PUNCT
admet-520	95	16	more	more	ADV
admet-520	95	17	identified	identify	VERB
admet-520	95	18	spectra	spectra	NOUN
admet-520	95	19	,	,	PUNCT
admet-520	95	20	but	but	CCONJ
admet-520	95	21	a	a	DET
admet-520	95	22	lower	low	ADJ
admet-520	95	23	number	number	NOUN
admet-520	95	24	of	of	ADP
admet-520	95	25	unique	unique	ADJ
admet-520	95	26	peptide	peptide	NOUN
admet-520	95	27	ids	id	NOUN
admet-520	95	28	.	.	PUNCT
admet-520	96	1	figure	figure	NOUN
admet-520	96	2	3a	3a	PROPN
admet-520	96	3	shows	show	VERB
admet-520	96	4	the	the	DET
admet-520	96	5	correlation	correlation	NOUN
admet-520	96	6	between	between	ADP
admet-520	96	7	retention	retention	NOUN
admet-520	96	8	time	time	NOUN
admet-520	96	9	(	(	PUNCT
admet-520	96	10	fraction	fraction	NOUN
admet-520	96	11	number	number	NOUN
admet-520	96	12	)	)	PUNCT
admet-520	96	13	on	on	ADP
admet-520	96	14	the	the	DET
admet-520	96	15	two	two	NUM
admet-520	96	16	columns	column	NOUN
admet-520	96	17	.	.	PUNCT
admet-520	97	1	as	as	SCONJ
admet-520	97	2	expected	expect	VERB
admet-520	97	3	,	,	PUNCT
admet-520	97	4	a	a	DET
admet-520	97	5	significant	significant	ADJ
admet-520	97	6	portion	portion	NOUN
admet-520	97	7	of	of	ADP
admet-520	97	8	the	the	DET
admet-520	97	9	peptides	peptide	NOUN
admet-520	97	10	which	which	PRON
admet-520	97	11	show	show	VERB
admet-520	97	12	a	a	DET
admet-520	97	13	moderate	moderate	ADJ
admet-520	97	14	retention	retention	NOUN
admet-520	97	15	on	on	ADP
admet-520	97	16	luna	luna	PROPN
admet-520	97	17	c18	c18	PROPN
admet-520	97	18	,	,	PUNCT
admet-520	97	19	is	be	AUX
admet-520	97	20	not	not	PART
admet-520	97	21	retained	retain	VERB
admet-520	97	22	on	on	ADP
admet-520	97	23	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	97	24	and	and	CCONJ
admet-520	97	25	thus	thus	ADV
admet-520	97	26	elute	elute	VERB
admet-520	97	27	in	in	ADP
admet-520	97	28	the	the	DET
admet-520	97	29	early	early	ADJ
admet-520	97	30	fractions	fraction	NOUN
admet-520	97	31	.	.	PUNCT
admet-520	98	1	table	table	NOUN
admet-520	98	2	1	1	NUM
admet-520	98	3	.	.	PUNCT
admet-520	98	4	identification	identification	NOUN
admet-520	98	5	output	output	NOUN
admet-520	98	6	of	of	ADP
admet-520	98	7	2d	2d	NOUN
admet-520	98	8	(	(	PUNCT
admet-520	98	9	rp	rp	NOUN
admet-520	98	10	-	-	PUNCT
admet-520	98	11	rp	rp	NOUN
admet-520	98	12	)	)	PUNCT
admet-520	98	13	lc	lc	PROPN
admet-520	98	14	-	-	PUNCT
admet-520	98	15	ms	ms	PROPN
admet-520	98	16	/	/	SYM
admet-520	98	17	ms	ms	NOUN
admet-520	98	18	and	and	CCONJ
admet-520	98	19	2d	2d	NUM
admet-520	98	20	(	(	PUNCT
admet-520	98	21	iam.pc	iam.pc	NOUN
admet-520	98	22	-	-	PUNCT
admet-520	98	23	rp)-lc	rp)-lc	PROPN
admet-520	98	24	ms	ms	PROPN
admet-520	98	25	/	/	SYM
admet-520	98	26	ms	ms	NOUN
admet-520	98	27	for	for	ADP
admet-520	98	28	the	the	DET
admet-520	98	29	analysis	analysis	NOUN
admet-520	98	30	of	of	ADP
admet-520	98	31	whole	whole	ADJ
admet-520	98	32	cell	cell	NOUN
admet-520	98	33	yeast	yeast	NOUN
admet-520	98	34	tryptic	tryptic	ADJ
admet-520	98	35	digest	digest	NOUN
admet-520	98	36	.	.	PUNCT
admet-520	99	1	separation	separation	NOUN
admet-520	99	2	mode	mode	NOUN
admet-520	99	3	number	number	NOUN
admet-520	99	4	of	of	ADP
admet-520	99	5	fractions	fraction	NOUN
admet-520	99	6	total	total	NOUN
admet-520	99	7	lcms	lcms	PROPN
admet-520	99	8	time	time	NOUN
admet-520	99	9	(	(	PUNCT
admet-520	99	10	hr	hr	NOUN
admet-520	99	11	)	)	PUNCT
admet-520	99	12	amount	amount	NOUN
admet-520	99	13	injected	inject	VERB
admet-520	99	14	(	(	PUNCT
admet-520	99	15	g	g	NOUN
admet-520	99	16	)	)	PUNCT
admet-520	99	17	number	number	NOUN
admet-520	99	18	of	of	ADP
admet-520	99	19	ms	ms	PROPN
admet-520	99	20	/	/	SYM
admet-520	99	21	ms	ms	NOUN
admet-520	99	22	number	number	NOUN
admet-520	99	23	of	of	ADP
admet-520	99	24	identified	identify	VERB
admet-520	99	25	peptides	peptide	NOUN
admet-520	99	26	*	*	NOUN
admet-520	99	27	number	number	NOUN
admet-520	99	28	of	of	ADP
admet-520	99	29	nonredundant	nonredundant	ADJ
admet-520	99	30	peptide	peptide	NOUN
admet-520	99	31	ids	id	NOUN
admet-520	99	32	*	*	NOUN
admet-520	99	33	number	number	NOUN
admet-520	99	34	of	of	ADP
admet-520	99	35	protein	protein	NOUN
admet-520	99	36	ids	id	NOUN
admet-520	99	37	iam.pc	iam.pc	PROPN
admet-520	99	38	-	-	PUNCT
admet-520	99	39	rp	rp	NOUN
admet-520	99	40	40	40	NUM
admet-520	99	41	60	60	NUM
admet-520	99	42	~40	~40	NUM
admet-520	99	43	382972	382972	NUM
admet-520	99	44	229565	229565	NUM
admet-520	99	45	40602	40602	NUM
admet-520	99	46	4225	4225	NUM
admet-520	100	1	rp	rp	NOUN
admet-520	100	2	-	-	PUNCT
admet-520	100	3	rp	rp	NOUN
admet-520	100	4	45	45	NUM
admet-520	100	5	67.5	67.5	NUM
admet-520	100	6	~45	~45	NOUN
admet-520	100	7	312846	312846	NUM
admet-520	100	8	182435	182435	NUM
admet-520	100	9	43931	43931	NUM
admet-520	100	10	4295	4295	NUM
admet-520	100	11	*	*	PUNCT
admet-520	100	12	these	these	DET
admet-520	100	13	numbers	number	NOUN
admet-520	100	14	include	include	VERB
admet-520	100	15	~10	~10	PUNCT
admet-520	100	16	%	%	INTJ
admet-520	100	17	peptides	peptide	NOUN
admet-520	100	18	with	with	ADP
admet-520	100	19	post	post	ADJ
admet-520	100	20	-	-	ADJ
admet-520	100	21	translational	translational	ADJ
admet-520	100	22	modifications	modification	NOUN
admet-520	100	23	(	(	PUNCT
admet-520	100	24	default	default	NOUN
admet-520	100	25	settings	setting	NOUN
admet-520	100	26	of	of	ADP
admet-520	100	27	ptms	ptms	NOUN
admet-520	100	28	for	for	ADP
admet-520	100	29	x!tandem	x!tandem	PROPN
admet-520	100	30	was	be	AUX
admet-520	100	31	used	use	VERB
admet-520	100	32	(	(	PUNCT
admet-520	100	33	methionine	methionine	NOUN
admet-520	100	34	oxidation	oxidation	NOUN
admet-520	100	35	,	,	PUNCT
admet-520	100	36	deamidation	deamidation	NOUN
admet-520	100	37	and	and	CCONJ
admet-520	100	38	n	n	CCONJ
admet-520	100	39	-	-	PUNCT
admet-520	100	40	terminal	terminal	ADJ
admet-520	100	41	cyclization	cyclization	NOUN
admet-520	100	42	of	of	ADP
admet-520	100	43	cys	cys	PROPN
admet-520	100	44	and	and	CCONJ
admet-520	100	45	gln	gln	PROPN
admet-520	100	46	)	)	PUNCT
admet-520	100	47	,	,	PUNCT
admet-520	100	48	which	which	PRON
admet-520	100	49	were	be	AUX
admet-520	100	50	excluded	exclude	VERB
admet-520	100	51	from	from	ADP
admet-520	100	52	the	the	DET
admet-520	100	53	retention	retention	NOUN
admet-520	100	54	modelling	modelling	NOUN
admet-520	100	55	.	.	PUNCT
admet-520	101	1	optimization	optimization	NOUN
admet-520	101	2	of	of	ADP
admet-520	101	3	peptide	peptide	ADJ
admet-520	101	4	retention	retention	NOUN
admet-520	101	5	prediction	prediction	NOUN
admet-520	101	6	models	model	VERB
admet-520	101	7	the	the	DET
admet-520	101	8	optimization	optimization	NOUN
admet-520	101	9	of	of	ADP
admet-520	101	10	the	the	DET
admet-520	101	11	peptide	peptide	NOUN
admet-520	101	12	retention	retention	NOUN
admet-520	101	13	prediction	prediction	NOUN
admet-520	101	14	models	model	NOUN
admet-520	101	15	has	have	AUX
admet-520	101	16	been	be	AUX
admet-520	101	17	performed	perform	VERB
admet-520	101	18	using	use	VERB
admet-520	101	19	the	the	DET
admet-520	101	20	standard	standard	ADJ
admet-520	101	21	ssrcalc	ssrcalc	ADJ
admet-520	101	22	workflow	workflow	NOUN
admet-520	102	1	[	[	X
admet-520	102	2	21,22	21,22	NOUN
admet-520	102	3	]	]	X
admet-520	102	4	:	:	PUNCT
admet-520	102	5	1	1	X
admet-520	102	6	)	)	PUNCT
admet-520	102	7	retention	retention	NOUN
admet-520	102	8	coefficients	coefficient	NOUN
admet-520	102	9	for	for	ADP
admet-520	102	10	individual	individual	ADJ
admet-520	102	11	amino	amino	ADJ
admet-520	102	12	acids	acid	NOUN
admet-520	102	13	were	be	AUX
admet-520	102	14	optimized	optimize	VERB
admet-520	102	15	to	to	PART
admet-520	102	16	produce	produce	VERB
admet-520	102	17	the	the	DET
admet-520	102	18	best	good	ADJ
admet-520	102	19	fit	fit	NOUN
admet-520	102	20	for	for	ADP
admet-520	102	21	experimental	experimental	ADJ
admet-520	102	22	admet	admet	PROPN
admet-520	102	23	&	&	CCONJ
admet-520	102	24	dmpk	dmpk	PROPN
admet-520	102	25	6(2	6(2	NUM
admet-520	102	26	)	)	PUNCT
admet-520	102	27	(	(	PUNCT
admet-520	102	28	2018	2018	NUM
admet-520	102	29	)	)	PUNCT
admet-520	102	30	190	190	NUM
admet-520	102	31	-	-	SYM
admet-520	102	32	199	199	NUM
admet-520	102	33	peptide	peptide	NOUN
admet-520	102	34	retention	retention	NOUN
admet-520	102	35	time	time	NOUN
admet-520	102	36	prediction	prediction	NOUN
admet-520	102	37	for	for	ADP
admet-520	102	38	iam.pc	iam.pc	PROPN
admet-520	102	39	stationary	stationary	ADJ
admet-520	102	40	phases	phase	NOUN
admet-520	102	41	doi	doi	NOUN
admet-520	102	42	:	:	PUNCT
admet-520	102	43	10.5599	10.5599	NUM
admet-520	102	44	/	/	SYM
admet-520	102	45	admet.520	admet.520	NUM
admet-520	102	46	195	195	NUM
admet-520	102	47	vs.	vs.	ADP
admet-520	102	48	predicted	predict	VERB
admet-520	102	49	retention	retention	NOUN
admet-520	102	50	values	value	NOUN
admet-520	102	51	plot	plot	NOUN
admet-520	102	52	using	use	VERB
admet-520	102	53	an	an	DET
admet-520	102	54	additive	additive	ADJ
admet-520	102	55	model	model	NOUN
admet-520	102	56	with	with	ADP
admet-520	102	57	peptide	peptide	ADJ
admet-520	102	58	length	length	NOUN
admet-520	102	59	correction	correction	NOUN
admet-520	102	60	.	.	PUNCT
admet-520	103	1	2	2	X
admet-520	103	2	)	)	PUNCT
admet-520	103	3	position	position	NOUN
admet-520	103	4	-	-	PUNCT
admet-520	103	5	dependent	dependent	ADJ
admet-520	103	6	retention	retention	NOUN
admet-520	103	7	coefficients	coefficient	NOUN
admet-520	103	8	have	have	AUX
admet-520	103	9	been	be	AUX
admet-520	103	10	introduced	introduce	VERB
admet-520	103	11	for	for	ADP
admet-520	103	12	four	four	NUM
admet-520	103	13	terminal	terminal	ADJ
admet-520	103	14	positions	position	NOUN
admet-520	103	15	from	from	ADP
admet-520	103	16	each	each	DET
admet-520	103	17	terminus	terminus	NOUN
admet-520	103	18	.	.	PUNCT
admet-520	104	1	3	3	X
admet-520	104	2	)	)	PUNCT
admet-520	104	3	sequence	sequence	NOUN
admet-520	104	4	-	-	PUNCT
admet-520	104	5	dependent	dependent	ADJ
admet-520	104	6	corrections	correction	NOUN
admet-520	104	7	related	relate	VERB
admet-520	104	8	to	to	ADP
admet-520	104	9	peptide	peptide	NOUN
admet-520	104	10	helicity	helicity	NOUN
admet-520	104	11	and	and	CCONJ
admet-520	104	12	presence	presence	NOUN
admet-520	104	13	of	of	ADP
admet-520	104	14	hydrophobic	hydrophobic	NOUN
admet-520	104	15	clusters	cluster	NOUN
admet-520	104	16	were	be	AUX
admet-520	104	17	applied	apply	VERB
admet-520	104	18	in	in	ADP
admet-520	104	19	an	an	DET
admet-520	104	20	attempt	attempt	NOUN
admet-520	104	21	to	to	PART
admet-520	104	22	improve	improve	VERB
admet-520	104	23	correlations	correlation	NOUN
admet-520	104	24	.	.	PUNCT
admet-520	105	1	it	it	PRON
admet-520	105	2	should	should	AUX
admet-520	105	3	be	be	AUX
admet-520	105	4	noted	note	VERB
admet-520	105	5	,	,	PUNCT
admet-520	105	6	that	that	SCONJ
admet-520	105	7	modelling	model	VERB
admet-520	105	8	peptide	peptide	NOUN
admet-520	105	9	helicity	helicity	NOUN
admet-520	105	10	in	in	ADP
admet-520	105	11	reversed	reversed	ADJ
admet-520	105	12	-	-	PUNCT
admet-520	105	13	phase	phase	NOUN
admet-520	105	14	separations	separation	NOUN
admet-520	105	15	still	still	ADV
admet-520	105	16	represents	represent	VERB
admet-520	105	17	a	a	DET
admet-520	105	18	major	major	ADJ
admet-520	105	19	problem	problem	NOUN
admet-520	105	20	and	and	CCONJ
admet-520	105	21	has	have	AUX
admet-520	105	22	not	not	PART
admet-520	105	23	been	be	AUX
admet-520	105	24	fully	fully	ADV
admet-520	105	25	implemented	implement	VERB
admet-520	105	26	in	in	ADP
admet-520	105	27	the	the	DET
admet-520	105	28	ssrcalc	ssrcalc	ADJ
admet-520	105	29	model	model	NOUN
admet-520	105	30	.	.	PUNCT
admet-520	106	1	in	in	ADP
admet-520	106	2	this	this	DET
admet-520	106	3	work	work	NOUN
admet-520	106	4	,	,	PUNCT
admet-520	106	5	we	we	PRON
admet-520	106	6	have	have	AUX
admet-520	106	7	used	use	VERB
admet-520	106	8	our	our	PRON
admet-520	106	9	helicity	helicity	NOUN
admet-520	106	10	model	model	NOUN
admet-520	106	11	developed	develop	VERB
admet-520	106	12	for	for	ADP
admet-520	106	13	acidic	acidic	ADJ
admet-520	106	14	c18	c18	NOUN
admet-520	106	15	conditions	condition	NOUN
admet-520	106	16	and	and	CCONJ
admet-520	106	17	applied	apply	VERB
admet-520	106	18	it	it	PRON
admet-520	106	19	directly	directly	ADV
admet-520	106	20	to	to	ADP
admet-520	106	21	c18	c18	NOUN
admet-520	106	22	at	at	ADP
admet-520	106	23	ph7.4	ph7.4	PROPN
admet-520	106	24	.	.	PUNCT
admet-520	107	1	it	it	PRON
admet-520	107	2	's	be	AUX
admet-520	107	3	application	application	NOUN
admet-520	107	4	to	to	ADP
admet-520	107	5	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	107	6	data	datum	NOUN
admet-520	107	7	(	(	PUNCT
admet-520	107	8	not	not	PART
admet-520	107	9	shown	show	VERB
admet-520	107	10	here	here	ADV
admet-520	107	11	)	)	PUNCT
admet-520	107	12	did	do	VERB
admet-520	107	13	not	not	PART
admet-520	107	14	a	a	DET
admet-520	107	15	provide	provide	VERB
admet-520	107	16	significant	significant	ADJ
admet-520	107	17	improvement	improvement	NOUN
admet-520	107	18	.	.	PUNCT
admet-520	108	1	therefore	therefore	ADV
admet-520	108	2	,	,	PUNCT
admet-520	108	3	we	we	PRON
admet-520	108	4	applied	apply	VERB
admet-520	108	5	its	its	PRON
admet-520	108	6	simplified	simplified	ADJ
admet-520	108	7	version	version	NOUN
admet-520	108	8	(	(	PUNCT
admet-520	108	9	counting	count	VERB
admet-520	108	10	i	i	PRON
admet-520	108	11	–	–	PUNCT
admet-520	108	12	i+3	i+3	NOUN
admet-520	108	13	;	;	PUNCT
admet-520	108	14	i	i	PRON
admet-520	108	15	–	–	PUNCT
admet-520	108	16	i+4	i+4	NUM
admet-520	108	17	interactions	interaction	NOUN
admet-520	108	18	of	of	ADP
admet-520	108	19	hydrophobic	hydrophobic	NOUN
admet-520	108	20	residues	residue	NOUN
admet-520	108	21	)	)	PUNCT
admet-520	108	22	to	to	ADP
admet-520	108	23	the	the	DET
admet-520	108	24	phospholipid	phospholipid	NOUN
admet-520	108	25	phase	phase	NOUN
admet-520	108	26	data	datum	NOUN
admet-520	108	27	.	.	PUNCT
admet-520	109	1	figure	figure	NOUN
admet-520	109	2	3	3	NUM
admet-520	109	3	.	.	PUNCT
admet-520	110	1	representation	representation	NOUN
admet-520	110	2	of	of	ADP
admet-520	110	3	the	the	DET
admet-520	110	4	separation	separation	NOUN
admet-520	110	5	space	space	NOUN
admet-520	110	6	of	of	ADP
admet-520	110	7	tryptic	tryptic	ADJ
admet-520	110	8	peptides	peptide	NOUN
admet-520	110	9	on	on	ADP
admet-520	110	10	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	110	11	and	and	CCONJ
admet-520	110	12	c18	c18	NOUN
admet-520	110	13	,	,	PUNCT
admet-520	110	14	and	and	CCONJ
admet-520	110	15	their	their	PRON
admet-520	110	16	respective	respective	ADJ
admet-520	110	17	ssrcalc	ssrcalc	ADJ
admet-520	110	18	model	model	NOUN
admet-520	110	19	accuracy	accuracy	NOUN
admet-520	110	20	.	.	PUNCT
admet-520	111	1	a	a	DET
admet-520	111	2	–	–	PUNCT
admet-520	111	3	correlation	correlation	NOUN
admet-520	111	4	between	between	ADP
admet-520	111	5	the	the	DET
admet-520	111	6	retention	retention	NOUN
admet-520	111	7	times	time	NOUN
admet-520	111	8	(	(	PUNCT
admet-520	111	9	fraction	fraction	NOUN
admet-520	111	10	number	number	NOUN
admet-520	111	11	)	)	PUNCT
admet-520	111	12	for	for	ADP
admet-520	111	13	the	the	DET
admet-520	111	14	two	two	NUM
admet-520	111	15	chromatographic	chromatographic	ADJ
admet-520	111	16	systems	system	NOUN
admet-520	111	17	(	(	PUNCT
admet-520	111	18	26,594	26,594	NUM
admet-520	111	19	peptides	peptide	NOUN
admet-520	111	20	identified	identify	VERB
admet-520	111	21	in	in	ADP
admet-520	111	22	both	both	DET
admet-520	111	23	runs	run	NOUN
admet-520	111	24	)	)	PUNCT
admet-520	111	25	;	;	PUNCT
admet-520	111	26	b	b	X
admet-520	111	27	and	and	CCONJ
admet-520	111	28	c	c	PROPN
admet-520	111	29	–	–	PUNCT
admet-520	111	30	the	the	DET
admet-520	111	31	accuracy	accuracy	NOUN
admet-520	111	32	of	of	ADP
admet-520	111	33	the	the	DET
admet-520	111	34	custom	custom	NOUN
admet-520	111	35	versions	version	NOUN
admet-520	111	36	of	of	ADP
admet-520	111	37	the	the	DET
admet-520	111	38	ssrcalc	ssrcalc	ADJ
admet-520	111	39	model	model	NOUN
admet-520	111	40	for	for	ADP
admet-520	111	41	the	the	DET
admet-520	111	42	luna	luna	PROPN
admet-520	111	43	c18(2	c18(2	PROPN
admet-520	111	44	)	)	PUNCT
admet-520	111	45	(	(	PUNCT
admet-520	111	46	40,105	40,105	NUM
admet-520	111	47	peptides	peptide	NOUN
admet-520	111	48	)	)	PUNCT
admet-520	111	49	and	and	CCONJ
admet-520	111	50	the	the	DET
admet-520	111	51	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	111	52	(	(	PUNCT
admet-520	111	53	28,558	28,558	NUM
admet-520	111	54	)	)	PUNCT
admet-520	111	55	,	,	PUNCT
admet-520	111	56	respectively	respectively	ADV
admet-520	111	57	.	.	PUNCT
admet-520	112	1	resulting	result	VERB
admet-520	112	2	correlation	correlation	NOUN
admet-520	112	3	plots	plot	NOUN
admet-520	112	4	for	for	ADP
admet-520	112	5	luna	luna	PROPN
admet-520	112	6	c18(2	c18(2	PROPN
admet-520	112	7	)	)	PUNCT
admet-520	112	8	and	and	CCONJ
admet-520	112	9	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	112	10	are	be	AUX
admet-520	112	11	shown	show	VERB
admet-520	112	12	in	in	ADP
admet-520	112	13	figure	figure	NOUN
admet-520	112	14	3b	3b	NOUN
admet-520	112	15	and	and	CCONJ
admet-520	112	16	3c	3c	NUM
admet-520	112	17	,	,	PUNCT
admet-520	112	18	respectively	respectively	ADV
admet-520	112	19	.	.	PUNCT
admet-520	113	1	the	the	DET
admet-520	113	2	final	final	ADJ
admet-520	113	3	model	model	NOUN
admet-520	113	4	accuracy	accuracy	NOUN
admet-520	113	5	for	for	ADP
admet-520	113	6	the	the	DET
admet-520	113	7	c18	c18	NOUN
admet-520	113	8	packing	packing	NOUN
admet-520	113	9	material	material	NOUN
admet-520	113	10	was	be	AUX
admet-520	113	11	found	find	VERB
admet-520	113	12	to	to	PART
admet-520	113	13	be	be	AUX
admet-520	113	14	similar	similar	ADJ
admet-520	113	15	to	to	ADP
admet-520	113	16	other	other	ADJ
admet-520	113	17	ssrcalc	ssrcalc	NOUN
admet-520	113	18	models	model	NOUN
admet-520	113	19	for	for	ADP
admet-520	113	20	c18	c18	NOUN
admet-520	113	21	separations	separation	NOUN
admet-520	113	22	(	(	PUNCT
admet-520	113	23	r2	r2	NOUN
admet-520	113	24	-	-	PUNCT
admet-520	113	25	value	value	NOUN
admet-520	113	26	0.96	0.96	NUM
admet-520	113	27	)	)	PUNCT
admet-520	113	28	.	.	PUNCT
admet-520	114	1	it	it	PRON
admet-520	114	2	should	should	AUX
admet-520	114	3	be	be	AUX
admet-520	114	4	noted	note	VERB
admet-520	114	5	,	,	PUNCT
admet-520	114	6	that	that	SCONJ
admet-520	114	7	only	only	ADV
admet-520	114	8	peptide	peptide	VERB
admet-520	114	9	,	,	PUNCT
admet-520	114	10	with	with	ADP
admet-520	114	11	a	a	DET
admet-520	114	12	retention	retention	NOUN
admet-520	114	13	of	of	ADP
admet-520	114	14	3	3	NUM
admet-520	114	15	min	min	NOUN
admet-520	114	16	and	and	CCONJ
admet-520	114	17	higher	high	ADJ
admet-520	114	18	were	be	AUX
admet-520	114	19	used	use	VERB
admet-520	114	20	for	for	ADP
admet-520	114	21	the	the	DET
admet-520	114	22	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	114	23	model	model	NOUN
admet-520	114	24	development	development	NOUN
admet-520	114	25	.	.	PUNCT
admet-520	115	1	peptides	peptide	NOUN
admet-520	115	2	with	with	ADP
admet-520	115	3	lower	low	ADJ
admet-520	115	4	retention	retention	NOUN
admet-520	115	5	were	be	AUX
admet-520	115	6	considered	consider	VERB
admet-520	115	7	unretained	unretained	ADJ
admet-520	115	8	under	under	ADP
admet-520	115	9	the	the	DET
admet-520	115	10	chromatographic	chromatographic	ADJ
admet-520	115	11	conditions	condition	NOUN
admet-520	115	12	used	use	VERB
admet-520	115	13	and	and	CCONJ
admet-520	115	14	therefore	therefore	ADV
admet-520	115	15	their	their	PRON
admet-520	115	16	retention	retention	NOUN
admet-520	115	17	values	value	NOUN
admet-520	115	18	could	could	AUX
admet-520	115	19	not	not	PART
admet-520	115	20	be	be	AUX
admet-520	115	21	accurately	accurately	ADV
admet-520	115	22	assigned	assign	VERB
admet-520	115	23	.	.	PUNCT
admet-520	116	1	therefore	therefore	ADV
admet-520	116	2	,	,	PUNCT
admet-520	116	3	out	out	ADP
admet-520	116	4	of	of	ADP
admet-520	116	5	37,327	37,327	NUM
admet-520	116	6	non	non	ADJ
admet-520	116	7	-	-	ADJ
admet-520	116	8	modified	modified	ADJ
admet-520	116	9	tryptic	tryptic	ADJ
admet-520	116	10	peptides	peptide	NOUN
admet-520	116	11	identified	identify	VERB
admet-520	116	12	only	only	ADV
admet-520	116	13	28,558	28,558	NUM
admet-520	116	14	were	be	AUX
admet-520	116	15	used	use	VERB
admet-520	116	16	for	for	ADP
admet-520	116	17	modelling	modelling	NOUN
admet-520	116	18	as	as	SCONJ
admet-520	116	19	shown	show	VERB
admet-520	116	20	in	in	ADP
admet-520	116	21	figure	figure	NOUN
admet-520	116	22	3c	3c	NUM
admet-520	116	23	.	.	PUNCT
admet-520	117	1	the	the	DET
admet-520	117	2	accuracy	accuracy	NOUN
admet-520	117	3	of	of	ADP
admet-520	117	4	the	the	DET
admet-520	117	5	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	117	6	algorithm	algorithm	NOUN
admet-520	117	7	is	be	AUX
admet-520	117	8	lower	low	ADJ
admet-520	117	9	than	than	ADP
admet-520	117	10	that	that	PRON
admet-520	117	11	for	for	ADP
admet-520	117	12	the	the	DET
admet-520	117	13	c18	c18	NOUN
admet-520	117	14	column	column	NOUN
admet-520	117	15	due	due	ADP
admet-520	117	16	to	to	ADP
admet-520	117	17	a	a	DET
admet-520	117	18	narrower	narrow	ADJ
admet-520	117	19	range	range	NOUN
admet-520	117	20	of	of	ADP
admet-520	117	21	peptide	peptide	ADJ
admet-520	117	22	elution	elution	NOUN
admet-520	117	23	(	(	PUNCT
admet-520	117	24	~30	~30	X
admet-520	117	25	%	%	X
admet-520	117	26	acetonitrile	acetonitrile	NOUN
admet-520	117	27	vs.	vs.	CCONJ
admet-520	117	28	~40	~40	NOUN
admet-520	117	29	%	%	NOUN
admet-520	117	30	)	)	PUNCT
admet-520	117	31	and	and	CCONJ
admet-520	117	32	the	the	DET
admet-520	117	33	possible	possible	ADJ
admet-520	117	34	involvement	involvement	NOUN
admet-520	117	35	of	of	ADP
admet-520	117	36	novel	novel	ADJ
admet-520	117	37	sequence	sequence	NOUN
admet-520	117	38	-	-	PUNCT
admet-520	117	39	specific	specific	ADJ
admet-520	117	40	features	feature	NOUN
admet-520	117	41	of	of	ADP
admet-520	117	42	the	the	DET
admet-520	117	43	retention	retention	NOUN
admet-520	117	44	on	on	ADP
admet-520	117	45	the	the	DET
admet-520	117	46	phosphatidylcholine	phosphatidylcholine	NOUN
admet-520	117	47	stationary	stationary	ADJ
admet-520	117	48	phase	phase	NOUN
admet-520	117	49	,	,	PUNCT
admet-520	117	50	yet	yet	ADV
admet-520	117	51	to	to	PART
admet-520	117	52	be	be	AUX
admet-520	117	53	discovered	discover	VERB
admet-520	117	54	.	.	PUNCT
admet-520	118	1	retention	retention	NOUN
admet-520	118	2	coefficients	coefficient	NOUN
admet-520	118	3	(	(	PUNCT
admet-520	118	4	rc	rc	NOUN
admet-520	118	5	)	)	PUNCT
admet-520	118	6	retention	retention	NOUN
admet-520	118	7	coefficients	coefficient	NOUN
admet-520	118	8	(	(	PUNCT
admet-520	118	9	rc	rc	NOUN
admet-520	118	10	)	)	PUNCT
admet-520	118	11	represent	represent	VERB
admet-520	118	12	a	a	DET
admet-520	118	13	measure	measure	NOUN
admet-520	118	14	of	of	ADP
admet-520	118	15	the	the	DET
admet-520	118	16	participation	participation	NOUN
admet-520	118	17	of	of	ADP
admet-520	118	18	individual	individual	ADJ
admet-520	118	19	amino	amino	ADJ
admet-520	118	20	acids	acid	NOUN
admet-520	118	21	in	in	ADP
admet-520	118	22	the	the	DET
admet-520	118	23	peptide	peptide	ADJ
admet-520	118	24	retention	retention	NOUN
admet-520	118	25	on	on	ADP
admet-520	118	26	different	different	ADJ
admet-520	118	27	chromatographic	chromatographic	ADJ
admet-520	118	28	columns	column	NOUN
admet-520	118	29	.	.	PUNCT
admet-520	119	1	ssrcalc	ssrcalc	ADJ
admet-520	119	2	models	model	NOUN
admet-520	119	3	encode	encode	VERB
admet-520	119	4	rc	rc	PROPN
admet-520	119	5	for	for	ADP
admet-520	119	6	individual	individual	ADJ
admet-520	119	7	residues	residue	NOUN
admet-520	119	8	in	in	ADP
admet-520	119	9	a	a	DET
admet-520	119	10	position	position	NOUN
admet-520	119	11	-	-	PUNCT
admet-520	119	12	dependent	dependent	ADJ
admet-520	119	13	manner	manner	NOUN
admet-520	119	14	with	with	ADP
admet-520	119	15	four	four	NUM
admet-520	119	16	to	to	PART
admet-520	119	17	five	five	NUM
admet-520	119	18	nand	nand	NOUN
admet-520	119	19	c	c	NOUN
admet-520	119	20	-	-	PUNCT
admet-520	119	21	terminal	terminal	ADJ
admet-520	119	22	rc	rc	PROPN
admet-520	119	23	’s	’s	NOUN
admet-520	119	24	,	,	PUNCT
admet-520	119	25	and	and	CCONJ
admet-520	119	26	internal	internal	PROPN
admet-520	119	27	rc	rc	PROPN
admet-520	119	28	’s	’s	NOUN
admet-520	119	29	.	.	PUNCT
admet-520	120	1	since	since	SCONJ
admet-520	120	2	tryptic	tryptic	ADJ
admet-520	120	3	peptides	peptide	NOUN
admet-520	120	4	are	be	AUX
admet-520	120	5	fairly	fairly	ADV
admet-520	120	6	large	large	ADJ
admet-520	120	7	,	,	PUNCT
admet-520	120	8	the	the	DET
admet-520	120	9	latter	latter	NOUN
admet-520	120	10	represents	represent	VERB
admet-520	120	11	the	the	DET
admet-520	120	12	bulk	bulk	NOUN
admet-520	120	13	of	of	ADP
admet-520	120	14	the	the	DET
admet-520	120	15	residues	residue	NOUN
admet-520	120	16	and	and	CCONJ
admet-520	120	17	provide	provide	VERB
admet-520	120	18	the	the	DET
admet-520	120	19	most	most	ADV
admet-520	120	20	valuable	valuable	ADJ
admet-520	120	21	information	information	NOUN
admet-520	120	22	on	on	ADP
admet-520	120	23	the	the	DET
admet-520	120	24	contribution	contribution	NOUN
admet-520	120	25	of	of	ADP
admet-520	120	26	the	the	DET
admet-520	120	27	residues	residue	NOUN
admet-520	120	28	.	.	PUNCT
admet-520	121	1	figure	figure	NOUN
admet-520	121	2	4a	4a	NOUN
admet-520	121	3	shows	show	VERB
admet-520	121	4	the	the	DET
admet-520	121	5	comparison	comparison	NOUN
admet-520	121	6	of	of	ADP
admet-520	121	7	internal	internal	ADJ
admet-520	121	8	retention	retention	NOUN
admet-520	121	9	coefficients	coefficient	NOUN
admet-520	121	10	for	for	ADP
admet-520	121	11	c18	c18	NOUN
admet-520	121	12	and	and	CCONJ
admet-520	121	13	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	121	14	separations	separation	NOUN
admet-520	121	15	at	at	ADP
admet-520	121	16	ph	ph	PROPN
admet-520	121	17	7.4	7.4	NUM
admet-520	121	18	and	and	CCONJ
admet-520	121	19	establishes	establish	VERB
admet-520	121	20	the	the	DET
admet-520	121	21	difference	difference	NOUN
admet-520	121	22	in	in	ADP
admet-520	121	23	retention	retention	NOUN
admet-520	121	24	contributions	contribution	NOUN
admet-520	121	25	of	of	ADP
admet-520	121	26	amino	amino	ADJ
admet-520	121	27	acids	acid	NOUN
admet-520	121	28	.	.	PUNCT
admet-520	122	1	table	table	NOUN
admet-520	122	2	2	2	NUM
admet-520	122	3	additionally	additionally	ADV
admet-520	122	4	compares	compare	VERB
admet-520	122	5	these	these	DET
admet-520	122	6	values	value	NOUN
admet-520	122	7	to	to	ADP
admet-520	122	8	rp	rp	NOUN
admet-520	122	9	separations	separation	NOUN
admet-520	122	10	at	at	ADP
admet-520	122	11	acidic	acidic	ADJ
admet-520	122	12	and	and	CCONJ
admet-520	122	13	basic	basic	ADJ
admet-520	122	14	conditions	condition	NOUN
admet-520	122	15	.	.	PUNCT
admet-520	123	1	when	when	SCONJ
admet-520	123	2	analyzing	analyze	VERB
admet-520	123	3	figure	figure	NOUN
admet-520	123	4	4a	4a	NOUN
admet-520	123	5	,	,	PUNCT
admet-520	123	6	both	both	PRON
admet-520	123	7	hydrophobic	hydrophobic	NOUN
admet-520	123	8	character	character	NOUN
admet-520	123	9	and	and	CCONJ
admet-520	123	10	charge	charge	NOUN
admet-520	123	11	state	state	NOUN
admet-520	123	12	of	of	ADP
admet-520	123	13	the	the	DET
admet-520	123	14	residues	residue	NOUN
admet-520	123	15	oleg	oleg	PROPN
admet-520	124	1	krokhin	krokhin	PROPN
admet-520	124	2	et	et	PROPN
admet-520	124	3	al	al	PROPN
admet-520	124	4	.	.	PROPN
admet-520	124	5	admet	admet	PROPN
admet-520	124	6	&	&	CCONJ
admet-520	124	7	dmpk	dmpk	PROPN
admet-520	124	8	6(2	6(2	NUM
admet-520	124	9	)	)	PUNCT
admet-520	124	10	(	(	PUNCT
admet-520	124	11	2018	2018	NUM
admet-520	124	12	)	)	PUNCT
admet-520	124	13	190	190	NUM
admet-520	124	14	-	-	SYM
admet-520	124	15	199	199	NUM
admet-520	124	16	196	196	NUM
admet-520	124	17	should	should	AUX
admet-520	124	18	be	be	AUX
admet-520	124	19	taken	take	VERB
admet-520	124	20	into	into	ADP
admet-520	124	21	account	account	NOUN
admet-520	124	22	.	.	PUNCT
admet-520	125	1	the	the	DET
admet-520	125	2	amino	amino	NOUN
admet-520	125	3	acids	acid	NOUN
admet-520	125	4	usually	usually	ADV
admet-520	125	5	considered	consider	VERB
admet-520	125	6	to	to	PART
admet-520	125	7	be	be	AUX
admet-520	125	8	hydrophobic	hydrophobic	NOUN
admet-520	125	9	are	be	AUX
admet-520	125	10	shown	show	VERB
admet-520	125	11	in	in	ADP
admet-520	125	12	red	red	ADJ
admet-520	125	13	and	and	CCONJ
admet-520	125	14	hydrophilic	hydrophilic	NOUN
admet-520	125	15	in	in	ADP
admet-520	125	16	green	green	PROPN
admet-520	125	17	.	.	PUNCT
admet-520	126	1	at	at	ADP
admet-520	126	2	ph	ph	PROPN
admet-520	126	3	7.4	7.4	NUM
admet-520	126	4	arg	arg	NOUN
admet-520	126	5	and	and	CCONJ
admet-520	126	6	lys	lys	NOUN
admet-520	126	7	are	be	AUX
admet-520	126	8	protonated	protonate	VERB
admet-520	126	9	,	,	PUNCT
admet-520	126	10	his	his	PRON
admet-520	126	11	is	be	AUX
admet-520	126	12	neutral	neutral	ADJ
admet-520	126	13	,	,	PUNCT
admet-520	126	14	while	while	SCONJ
admet-520	126	15	asp	asp	PROPN
admet-520	126	16	and	and	CCONJ
admet-520	126	17	glu	glu	NOUN
admet-520	126	18	carry	carry	VERB
admet-520	126	19	a	a	DET
admet-520	126	20	negative	negative	ADJ
admet-520	126	21	charge	charge	NOUN
admet-520	126	22	.	.	PUNCT
admet-520	127	1	positively	positively	ADV
admet-520	127	2	charged	charge	VERB
admet-520	127	3	lys	lys	PROPN
admet-520	127	4	,	,	PUNCT
admet-520	127	5	arg	arg	NOUN
admet-520	127	6	and	and	CCONJ
admet-520	127	7	the	the	DET
admet-520	127	8	aromatic	aromatic	ADJ
admet-520	127	9	tyr	tyr	NOUN
admet-520	127	10	,	,	PUNCT
admet-520	127	11	his	his	PRON
admet-520	127	12	,	,	PUNCT
admet-520	127	13	and	and	CCONJ
admet-520	127	14	trp	trp	PROPN
admet-520	127	15	are	be	AUX
admet-520	127	16	among	among	ADP
admet-520	127	17	the	the	DET
admet-520	127	18	residues	residue	NOUN
admet-520	127	19	,	,	PUNCT
admet-520	127	20	which	which	PRON
admet-520	127	21	showed	show	VERB
admet-520	127	22	an	an	DET
admet-520	127	23	increase	increase	NOUN
admet-520	127	24	in	in	ADP
admet-520	127	25	interaction	interaction	NOUN
admet-520	127	26	on	on	ADP
admet-520	127	27	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	127	28	.	.	PUNCT
admet-520	128	1	at	at	ADP
admet-520	128	2	the	the	DET
admet-520	128	3	same	same	ADJ
admet-520	128	4	time	time	NOUN
admet-520	128	5	negatively	negatively	ADV
admet-520	128	6	charged	charge	VERB
admet-520	128	7	glu	glu	NOUN
admet-520	128	8	and	and	CCONJ
admet-520	128	9	asp	asp	PROPN
admet-520	128	10	exhibit	exhibit	NOUN
admet-520	128	11	reduced	reduce	VERB
admet-520	128	12	interaction	interaction	NOUN
admet-520	128	13	.	.	PUNCT
admet-520	129	1	this	this	PRON
admet-520	129	2	suggests	suggest	VERB
admet-520	129	3	that	that	SCONJ
admet-520	129	4	additional	additional	ADJ
admet-520	129	5	electrostatic	electrostatic	ADJ
admet-520	129	6	interactions	interaction	NOUN
admet-520	129	7	with	with	ADP
admet-520	129	8	glycerophosphate	glycerophosphate	NOUN
admet-520	129	9	groups	group	NOUN
admet-520	129	10	play	play	VERB
admet-520	129	11	a	a	DET
admet-520	129	12	major	major	ADJ
admet-520	129	13	role	role	NOUN
admet-520	129	14	in	in	ADP
admet-520	129	15	the	the	DET
admet-520	129	16	separation	separation	NOUN
admet-520	129	17	through	through	ADP
admet-520	129	18	the	the	DET
admet-520	129	19	attraction	attraction	NOUN
admet-520	129	20	of	of	ADP
admet-520	129	21	lys	lys	NOUN
admet-520	129	22	and	and	CCONJ
admet-520	129	23	arg	arg	NOUN
admet-520	129	24	and	and	CCONJ
admet-520	129	25	repulsion	repulsion	NOUN
admet-520	129	26	of	of	ADP
admet-520	129	27	asp	asp	PROPN
admet-520	129	28	and	and	CCONJ
admet-520	129	29	glu	glu	PROPN
admet-520	129	30	.	.	PUNCT
admet-520	130	1	the	the	DET
admet-520	130	2	increased	increase	VERB
admet-520	130	3	interaction	interaction	NOUN
admet-520	130	4	of	of	ADP
admet-520	130	5	aromatic	aromatic	ADJ
admet-520	130	6	residues	residue	NOUN
admet-520	130	7	on	on	ADP
admet-520	130	8	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	130	9	is	be	AUX
admet-520	130	10	most	most	ADV
admet-520	130	11	likely	likely	ADV
admet-520	130	12	caused	cause	VERB
admet-520	130	13	by	by	ADP
admet-520	130	14	the	the	DET
admet-520	130	15	delocalization	delocalization	NOUN
admet-520	130	16	of	of	ADP
admet-520	130	17	the	the	DET
admet-520	130	18	negative	negative	ADJ
admet-520	130	19	charge	charge	NOUN
admet-520	130	20	on	on	ADP
admet-520	130	21	the	the	DET
admet-520	130	22	phosphate	phosphate	ADJ
admet-520	130	23	groups	group	NOUN
admet-520	130	24	through	through	ADP
admet-520	130	25	the	the	DET
admet-520	130	26	formation	formation	NOUN
admet-520	130	27	of	of	ADP
admet-520	130	28	a	a	DET
admet-520	130	29	hydrogen	hydrogen	NOUN
admet-520	130	30	bond	bond	NOUN
admet-520	130	31	.	.	PUNCT
admet-520	131	1	figure	figure	NOUN
admet-520	131	2	4	4	NUM
admet-520	131	3	.	.	PUNCT
admet-520	132	1	retention	retention	NOUN
admet-520	132	2	contributions	contribution	NOUN
admet-520	132	3	of	of	ADP
admet-520	132	4	individual	individual	ADJ
admet-520	132	5	residues	residue	NOUN
admet-520	132	6	in	in	ADP
admet-520	132	7	peptide	peptide	ADJ
admet-520	132	8	retention	retention	NOUN
admet-520	132	9	on	on	ADP
admet-520	132	10	c18	c18	NOUN
admet-520	132	11	and	and	CCONJ
admet-520	132	12	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	132	13	phases	phase	NOUN
admet-520	132	14	at	at	ADP
admet-520	132	15	ph	ph	PROPN
admet-520	132	16	7.4	7.4	NUM
admet-520	132	17	.	.	PUNCT
admet-520	133	1	a	a	DET
admet-520	133	2	–	–	PUNCT
admet-520	133	3	comparison	comparison	NOUN
admet-520	133	4	of	of	ADP
admet-520	133	5	retention	retention	NOUN
admet-520	133	6	coefficients	coefficient	NOUN
admet-520	133	7	for	for	ADP
admet-520	133	8	the	the	DET
admet-520	133	9	two	two	NUM
admet-520	133	10	columns	column	NOUN
admet-520	133	11	;	;	PUNCT
admet-520	133	12	b	b	NUM
admet-520	133	13	and	and	CCONJ
admet-520	133	14	c	c	PROPN
admet-520	133	15	–	–	PUNCT
admet-520	133	16	position	position	NOUN
admet-520	133	17	-	-	PUNCT
admet-520	133	18	dependent	dependent	ADJ
admet-520	133	19	retention	retention	NOUN
admet-520	133	20	coefficients	coefficient	NOUN
admet-520	133	21	for	for	ADP
admet-520	133	22	selected	select	VERB
admet-520	133	23	amino	amino	ADJ
admet-520	133	24	acids	acid	NOUN
admet-520	133	25	for	for	ADP
admet-520	133	26	luna	luna	PROPN
admet-520	133	27	c18(2	c18(2	PROPN
admet-520	133	28	)	)	PUNCT
admet-520	133	29	and	and	CCONJ
admet-520	133	30	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	133	31	columns	column	NOUN
admet-520	133	32	,	,	PUNCT
admet-520	133	33	respectively	respectively	ADV
admet-520	133	34	.	.	PUNCT
admet-520	134	1	the	the	DET
admet-520	134	2	contribution	contribution	NOUN
admet-520	134	3	of	of	ADP
admet-520	134	4	the	the	DET
admet-520	134	5	different	different	ADJ
admet-520	134	6	amino	amino	NOUN
admet-520	134	7	acids	acid	NOUN
admet-520	134	8	to	to	PART
admet-520	134	9	peptide	peptide	VERB
admet-520	134	10	retention	retention	NOUN
admet-520	134	11	is	be	AUX
admet-520	134	12	often	often	ADV
admet-520	134	13	found	find	VERB
admet-520	134	14	to	to	PART
admet-520	134	15	be	be	AUX
admet-520	134	16	position	position	NOUN
admet-520	134	17	dependent	dependent	ADJ
admet-520	134	18	[	[	X
admet-520	134	19	17	17	NUM
admet-520	134	20	,	,	PUNCT
admet-520	134	21	21	21	NUM
admet-520	134	22	,	,	PUNCT
admet-520	134	23	22	22	NUM
admet-520	134	24	]	]	PUNCT
admet-520	134	25	.	.	PUNCT
admet-520	135	1	these	these	DET
admet-520	135	2	effects	effect	NOUN
admet-520	135	3	occur	occur	VERB
admet-520	135	4	due	due	ADP
admet-520	135	5	to	to	ADP
admet-520	135	6	various	various	ADJ
admet-520	135	7	mechanisms	mechanism	NOUN
admet-520	135	8	such	such	ADJ
admet-520	135	9	as	as	ADP
admet-520	135	10	ion	ion	NOUN
admet-520	135	11	-	-	PUNCT
admet-520	135	12	pairing	pairing	NOUN
admet-520	135	13	at	at	ADP
admet-520	135	14	positively	positively	ADV
admet-520	135	15	charged	charge	VERB
admet-520	135	16	n	n	CCONJ
admet-520	135	17	-	-	PUNCT
admet-520	135	18	terminus	terminus	NOUN
admet-520	135	19	[	[	X
admet-520	135	20	17	17	NUM
admet-520	135	21	]	]	PUNCT
admet-520	135	22	or	or	CCONJ
admet-520	135	23	the	the	DET
admet-520	135	24	peptide	peptide	NOUN
admet-520	135	25	orientation	orientation	NOUN
admet-520	135	26	effect	effect	NOUN
admet-520	135	27	[	[	X
admet-520	135	28	22	22	NUM
admet-520	135	29	]	]	PUNCT
admet-520	135	30	,	,	PUNCT
admet-520	135	31	characteristic	characteristic	ADJ
admet-520	135	32	in	in	ADP
admet-520	135	33	cation	cation	NOUN
admet-520	135	34	-	-	PUNCT
admet-520	135	35	exchange	exchange	NOUN
admet-520	135	36	peptide	peptide	NOUN
admet-520	135	37	separations	separation	NOUN
admet-520	135	38	.	.	PUNCT
admet-520	136	1	optimizing	optimize	VERB
admet-520	136	2	position	position	NOUN
admet-520	136	3	dependent	dependent	PROPN
admet-520	136	4	rc	rc	PROPN
admet-520	136	5	’s	’s	PART
admet-520	136	6	is	be	AUX
admet-520	136	7	a	a	DET
admet-520	136	8	mandatory	mandatory	ADJ
admet-520	136	9	procedure	procedure	NOUN
admet-520	136	10	for	for	ADP
admet-520	136	11	all	all	DET
admet-520	136	12	ssrcalc	ssrcalc	ADJ
admet-520	136	13	models	model	NOUN
admet-520	136	14	and	and	CCONJ
admet-520	136	15	was	be	AUX
admet-520	136	16	applied	apply	VERB
admet-520	136	17	in	in	ADP
admet-520	136	18	this	this	DET
admet-520	136	19	study	study	NOUN
admet-520	136	20	.	.	PUNCT
admet-520	137	1	figure	figure	NOUN
admet-520	137	2	4(b	4(b	NUM
admet-520	137	3	,	,	PUNCT
admet-520	137	4	c	c	NOUN
admet-520	137	5	)	)	PUNCT
admet-520	137	6	shows	show	VERB
admet-520	137	7	nine	nine	NUM
admet-520	137	8	position	position	NOUN
admet-520	137	9	dependent	dependent	ADJ
admet-520	137	10	rc	rc	PROPN
admet-520	137	11	values	value	NOUN
admet-520	137	12	(	(	PUNCT
admet-520	137	13	four	four	NUM
admet-520	137	14	on	on	ADP
admet-520	137	15	each	each	DET
admet-520	137	16	side	side	NOUN
admet-520	137	17	plus	plus	CCONJ
admet-520	137	18	internal	internal	ADJ
admet-520	137	19	)	)	PUNCT
admet-520	137	20	for	for	ADP
admet-520	137	21	selected	select	VERB
admet-520	137	22	residues	residue	NOUN
admet-520	137	23	:	:	PUNCT
admet-520	137	24	hydrophobic	hydrophobic	NOUN
admet-520	137	25	,	,	PUNCT
admet-520	137	26	negatively	negatively	ADV
admet-520	137	27	,	,	PUNCT
admet-520	137	28	and	and	CCONJ
admet-520	137	29	positively	positively	ADV
admet-520	137	30	charged	charge	VERB
admet-520	137	31	.	.	PUNCT
admet-520	138	1	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	138	2	does	do	AUX
admet-520	138	3	not	not	PART
admet-520	138	4	exhibit	exhibit	VERB
admet-520	138	5	significant	significant	ADJ
admet-520	138	6	position	position	NOUN
admet-520	138	7	-	-	PUNCT
admet-520	138	8	dependent	dependent	ADJ
admet-520	138	9	changes	change	NOUN
admet-520	138	10	except	except	SCONJ
admet-520	138	11	for	for	ADP
admet-520	138	12	a	a	DET
admet-520	138	13	small	small	ADJ
admet-520	138	14	decrease	decrease	NOUN
admet-520	138	15	of	of	ADP
admet-520	138	16	hydrophobic	hydrophobic	NOUN
admet-520	138	17	interactions	interaction	NOUN
admet-520	138	18	from	from	ADP
admet-520	138	19	the	the	DET
admet-520	138	20	nto	nto	PROPN
admet-520	138	21	c	c	NOUN
admet-520	138	22	-	-	PUNCT
admet-520	138	23	terminus	terminus	NOUN
admet-520	138	24	(	(	PUNCT
admet-520	138	25	figure	figure	NOUN
admet-520	138	26	4c	4c	NOUN
admet-520	138	27	)	)	PUNCT
admet-520	138	28	.	.	PUNCT
admet-520	139	1	respective	respective	ADJ
admet-520	139	2	plots	plot	NOUN
admet-520	139	3	for	for	ADP
admet-520	139	4	the	the	DET
admet-520	139	5	c18	c18	NOUN
admet-520	139	6	stationary	stationary	ADJ
admet-520	139	7	phase	phase	NOUN
admet-520	139	8	show	show	VERB
admet-520	139	9	a	a	DET
admet-520	139	10	substantial	substantial	ADJ
admet-520	139	11	increase	increase	NOUN
admet-520	139	12	in	in	ADP
admet-520	139	13	the	the	DET
admet-520	139	14	retention	retention	NOUN
admet-520	139	15	contribution	contribution	NOUN
admet-520	139	16	for	for	ADP
admet-520	139	17	arg	arg	NOUN
admet-520	139	18	and	and	CCONJ
admet-520	139	19	lys	lys	PROPN
admet-520	139	20	and	and	CCONJ
admet-520	139	21	increased	increase	VERB
admet-520	139	22	retention	retention	NOUN
admet-520	139	23	of	of	ADP
admet-520	139	24	the	the	DET
admet-520	139	25	hydrophobic	hydrophobic	NOUN
admet-520	139	26	residues	residue	NOUN
admet-520	139	27	for	for	ADP
admet-520	139	28	the	the	DET
admet-520	139	29	internal	internal	ADJ
admet-520	139	30	positions	position	NOUN
admet-520	139	31	(	(	PUNCT
admet-520	139	32	figure	figure	NOUN
admet-520	139	33	4b	4b	PROPN
admet-520	139	34	)	)	PUNCT
admet-520	139	35	.	.	PUNCT
admet-520	140	1	comparing	compare	VERB
admet-520	140	2	the	the	DET
admet-520	140	3	retention	retention	NOUN
admet-520	140	4	contribution	contribution	NOUN
admet-520	140	5	on	on	ADP
admet-520	140	6	the	the	DET
admet-520	140	7	luna	luna	PROPN
admet-520	140	8	c18(2	c18(2	PROPN
admet-520	140	9	)	)	PUNCT
admet-520	141	1	and	and	CCONJ
admet-520	141	2	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	141	3	columns	column	NOUN
admet-520	141	4	require	require	VERB
admet-520	141	5	understanding	understand	VERB
admet-520	141	6	the	the	DET
admet-520	141	7	differences	difference	NOUN
admet-520	141	8	in	in	ADP
admet-520	141	9	chemistry	chemistry	NOUN
admet-520	141	10	between	between	ADP
admet-520	141	11	the	the	DET
admet-520	141	12	two	two	NUM
admet-520	141	13	stationary	stationary	ADJ
admet-520	141	14	phases	phase	NOUN
admet-520	141	15	.	.	PUNCT
admet-520	142	1	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	142	2	is	be	AUX
admet-520	142	3	more	more	ADV
admet-520	142	4	hydrophilic	hydrophilic	ADJ
admet-520	142	5	because	because	SCONJ
admet-520	142	6	of	of	ADP
admet-520	142	7	its	its	PRON
admet-520	142	8	shorter	short	ADJ
admet-520	142	9	aliphatic	aliphatic	ADJ
admet-520	142	10	chain	chain	NOUN
admet-520	142	11	(	(	PUNCT
admet-520	142	12	c14	c14	NOUN
admet-520	142	13	vs.	vs.	ADP
admet-520	142	14	c18	c18	NOUN
admet-520	142	15	)	)	PUNCT
admet-520	142	16	,	,	PUNCT
admet-520	142	17	hydrophilic	hydrophilic	ADJ
admet-520	142	18	linkers	linker	NOUN
admet-520	142	19	and	and	CCONJ
admet-520	142	20	the	the	DET
admet-520	142	21	presence	presence	NOUN
admet-520	142	22	of	of	ADP
admet-520	142	23	a	a	DET
admet-520	142	24	zwitterionic	zwitterionic	ADJ
admet-520	142	25	head	head	NOUN
admet-520	142	26	group	group	NOUN
admet-520	142	27	.	.	PUNCT
admet-520	143	1	the	the	DET
admet-520	143	2	positively	positively	ADV
admet-520	143	3	charged	charge	VERB
admet-520	143	4	choline	choline	NOUN
admet-520	143	5	group	group	NOUN
admet-520	143	6	is	be	AUX
admet-520	143	7	located	locate	VERB
admet-520	143	8	on	on	ADP
admet-520	143	9	the	the	DET
admet-520	143	10	outside	outside	NOUN
admet-520	143	11	of	of	ADP
admet-520	143	12	the	the	DET
admet-520	143	13	functional	functional	ADJ
admet-520	143	14	admet	admet	NOUN
admet-520	143	15	&	&	CCONJ
admet-520	143	16	dmpk	dmpk	PROPN
admet-520	143	17	6(2	6(2	NUM
admet-520	143	18	)	)	PUNCT
admet-520	143	19	(	(	PUNCT
admet-520	143	20	2018	2018	NUM
admet-520	143	21	)	)	PUNCT
admet-520	143	22	190	190	NUM
admet-520	143	23	-	-	SYM
admet-520	143	24	199	199	NUM
admet-520	143	25	peptide	peptide	NOUN
admet-520	143	26	retention	retention	NOUN
admet-520	143	27	time	time	NOUN
admet-520	143	28	prediction	prediction	NOUN
admet-520	143	29	for	for	ADP
admet-520	143	30	iam.pc	iam.pc	PROPN
admet-520	143	31	stationary	stationary	ADJ
admet-520	143	32	phases	phase	NOUN
admet-520	143	33	doi	doi	NOUN
admet-520	143	34	:	:	PUNCT
admet-520	143	35	10.5599	10.5599	NUM
admet-520	143	36	/	/	SYM
admet-520	143	37	admet.520	admet.520	ADJ
admet-520	143	38	197	197	NUM
admet-520	143	39	layer	layer	NOUN
admet-520	143	40	,	,	PUNCT
admet-520	143	41	while	while	SCONJ
admet-520	143	42	the	the	DET
admet-520	143	43	negatively	negatively	ADV
admet-520	143	44	charged	charge	VERB
admet-520	143	45	glycerophosphate	glycerophosphate	NOUN
admet-520	143	46	is	be	AUX
admet-520	143	47	positioned	position	VERB
admet-520	143	48	below	below	ADP
admet-520	143	49	it	it	PRON
admet-520	143	50	;	;	PUNCT
admet-520	143	51	separated	separate	VERB
admet-520	143	52	by	by	ADP
admet-520	143	53	two	two	NUM
admet-520	143	54	additional	additional	ADJ
admet-520	143	55	methylene	methylene	NOUN
admet-520	143	56	groups	group	NOUN
admet-520	143	57	[	[	X
admet-520	143	58	4	4	NUM
admet-520	143	59	]	]	PUNCT
admet-520	143	60	.	.	PUNCT
admet-520	144	1	a	a	DET
admet-520	144	2	peptide	peptide	NOUN
admet-520	144	3	has	have	VERB
admet-520	144	4	to	to	PART
admet-520	144	5	penetrate	penetrate	VERB
admet-520	144	6	this	this	DET
admet-520	144	7	zwitterionic	zwitterionic	ADJ
admet-520	144	8	bilayer	bilayer	NOUN
admet-520	144	9	to	to	PART
admet-520	144	10	be	be	AUX
admet-520	144	11	partitioned	partition	VERB
admet-520	144	12	into	into	ADP
admet-520	144	13	the	the	DET
admet-520	144	14	hydrophobic	hydrophobic	NOUN
admet-520	144	15	environment	environment	NOUN
admet-520	144	16	.	.	PUNCT
admet-520	145	1	hydrophobic	hydrophobic	NOUN
admet-520	145	2	residues	residue	NOUN
admet-520	145	3	are	be	AUX
admet-520	145	4	found	find	VERB
admet-520	145	5	to	to	PART
admet-520	145	6	have	have	VERB
admet-520	145	7	greater	great	ADJ
admet-520	145	8	rc	rc	NOUN
admet-520	145	9	’s	’s	NOUN
admet-520	145	10	in	in	ADP
admet-520	145	11	figure	figure	NOUN
admet-520	145	12	4a	4a	NOUN
admet-520	145	13	,	,	PUNCT
admet-520	145	14	suggesting	suggest	VERB
admet-520	145	15	that	that	SCONJ
admet-520	145	16	the	the	DET
admet-520	145	17	majority	majority	NOUN
admet-520	145	18	of	of	ADP
admet-520	145	19	the	the	DET
admet-520	145	20	separation	separation	NOUN
admet-520	145	21	is	be	AUX
admet-520	145	22	driven	drive	VERB
admet-520	145	23	by	by	ADP
admet-520	145	24	hydrophobic	hydrophobic	NOUN
admet-520	145	25	interaction	interaction	NOUN
admet-520	145	26	on	on	ADP
admet-520	145	27	both	both	DET
admet-520	145	28	stationary	stationary	ADJ
admet-520	145	29	phases	phase	NOUN
admet-520	145	30	.	.	PUNCT
admet-520	146	1	the	the	DET
admet-520	146	2	differences	difference	NOUN
admet-520	146	3	in	in	ADP
admet-520	146	4	observed	observed	ADJ
admet-520	146	5	retention	retention	NOUN
admet-520	146	6	contributions	contribution	NOUN
admet-520	146	7	between	between	ADP
admet-520	146	8	c18	c18	NOUN
admet-520	146	9	and	and	CCONJ
admet-520	146	10	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	146	11	have	have	VERB
admet-520	146	12	to	to	PART
admet-520	146	13	come	come	VERB
admet-520	146	14	from	from	ADP
admet-520	146	15	the	the	DET
admet-520	146	16	interactions	interaction	NOUN
admet-520	146	17	of	of	ADP
admet-520	146	18	the	the	DET
admet-520	146	19	peptides	peptide	NOUN
admet-520	146	20	with	with	ADP
admet-520	146	21	the	the	DET
admet-520	146	22	zwitterionic	zwitterionic	ADJ
admet-520	146	23	head	head	NOUN
admet-520	146	24	group	group	NOUN
admet-520	146	25	.	.	PUNCT
admet-520	147	1	table	table	NOUN
admet-520	147	2	2	2	NUM
admet-520	147	3	.	.	PUNCT
admet-520	148	1	retention	retention	NOUN
admet-520	148	2	coefficients	coefficient	NOUN
admet-520	148	3	for	for	ADP
admet-520	148	4	ssrcalc	ssrcalc	ADJ
admet-520	148	5	peptide	peptide	NOUN
admet-520	148	6	retention	retention	NOUN
admet-520	148	7	prediction	prediction	NOUN
admet-520	148	8	models	model	NOUN
admet-520	148	9	in	in	ADP
admet-520	148	10	different	different	ADJ
admet-520	148	11	rp	rp	NOUN
admet-520	148	12	separation	separation	NOUN
admet-520	148	13	modes	mode	NOUN
admet-520	148	14	c18	c18	NOUN
admet-520	148	15	ph	ph	VERB
admet-520	148	16	7.4	7.4	NUM
admet-520	148	17	iam	iam	PROPN
admet-520	148	18	pc	pc	NOUN
admet-520	148	19	ph	ph	NOUN
admet-520	148	20	7.4	7.4	NUM
admet-520	148	21	c18	c18	NOUN
admet-520	148	22	formic	formic	ADJ
admet-520	148	23	acid	acid	PROPN
admet-520	149	1	[	[	X
admet-520	149	2	20	20	NUM
admet-520	149	3	]	]	PUNCT
admet-520	149	4	c18	c18	NOUN
admet-520	150	1	ph10	ph10	PROPN
admet-520	150	2	[	[	PUNCT
admet-520	150	3	20	20	NUM
admet-520	150	4	]	]	SYM
admet-520	150	5	w	w	PROPN
admet-520	150	6	10.73	10.73	NUM
admet-520	150	7	12.75	12.75	NUM
admet-520	150	8	35.74	35.74	NUM
admet-520	150	9	13.34	13.34	NUM
admet-520	150	10	f	f	PROPN
admet-520	150	11	9.89	9.89	NUM
admet-520	150	12	9.66	9.66	NUM
admet-520	150	13	32.99	32.99	NUM
admet-520	150	14	11.33	11.33	NUM
admet-520	150	15	l	l	NOUN
admet-520	150	16	8.52	8.52	NUM
admet-520	150	17	8.09	8.09	NUM
admet-520	150	18	30.57	30.57	NUM
admet-520	150	19	10.52	10.52	NUM
admet-520	150	20	i	i	NOUN
admet-520	150	21	7.56	7.56	NUM
admet-520	150	22	7.00	7.00	NUM
admet-520	150	23	27.75	27.75	NUM
admet-520	150	24	9.20	9.20	NUM
admet-520	150	25	m	m	NOUN
admet-520	150	26	6.31	6.31	NUM
admet-520	150	27	6.34	6.34	NUM
admet-520	150	28	21.32	21.32	NUM
admet-520	150	29	8.23	8.23	NUM
admet-520	150	30	y	y	PROPN
admet-520	150	31	5.15	5.15	NUM
admet-520	150	32	7.80	7.80	NUM
admet-520	150	33	16.69	16.69	NUM
admet-520	150	34	5.75	5.75	NUM
admet-520	150	35	v	v	NUM
admet-520	150	36	5.00	5.00	NUM
admet-520	150	37	4.58	4.58	NUM
admet-520	150	38	18.38	18.38	NUM
admet-520	150	39	6.28	6.28	NUM
admet-520	150	40	k	k	PROPN
admet-520	150	41	2.54	2.54	NUM
admet-520	150	42	8.07	8.07	NUM
admet-520	150	43	-6.24	-6.24	NUM
admet-520	150	44	4.34	4.34	NUM
admet-520	150	45	a	a	DET
admet-520	150	46	2.46	2.46	NUM
admet-520	150	47	2.51	2.51	NUM
admet-520	150	48	7.71	7.71	NUM
admet-520	150	49	2.59	2.59	NUM
admet-520	150	50	r	r	NOUN
admet-520	150	51	2.43	2.43	NUM
admet-520	150	52	9.97	9.97	NUM
admet-520	150	53	-1.66	-1.66	NUM
admet-520	150	54	5.35	5.35	NUM
admet-520	150	55	t	t	NOUN
admet-520	150	56	1.62	1.62	NUM
admet-520	150	57	1.65	1.65	NUM
admet-520	150	58	4.25	4.25	NUM
admet-520	150	59	1.93	1.93	NUM
admet-520	150	60	p	p	NOUN
admet-520	150	61	1.35	1.35	NUM
admet-520	150	62	1.07	1.07	NUM
admet-520	150	63	5.36	5.36	NUM
admet-520	150	64	1.26	1.26	NUM
admet-520	150	65	h	h	NOUN
admet-520	150	66	1.32	1.32	NUM
admet-520	150	67	3.68	3.68	NUM
admet-520	150	68	-5.16	-5.16	NUM
admet-520	150	69	3.03	3.03	NUM
admet-520	150	70	c	c	NOUN
admet-520	150	71	1.15	1.15	NUM
admet-520	150	72	1.75	1.75	NUM
admet-520	150	73	3.38	3.38	NUM
admet-520	150	74	1.71	1.71	NUM
admet-520	150	75	s	s	NOUN
admet-520	150	76	0.99	0.99	NUM
admet-520	150	77	1.55	1.55	NUM
admet-520	150	78	1.75	1.75	NUM
admet-520	150	79	1.03	1.03	NUM
admet-520	150	80	q	q	NOUN
admet-520	150	81	0.87	0.87	NUM
admet-520	150	82	1.33	1.33	NUM
admet-520	150	83	2.43	2.43	NUM
admet-520	150	84	1.10	1.10	NUM
admet-520	150	85	g	g	NOUN
admet-520	150	86	0.71	0.71	NUM
admet-520	150	87	0.93	0.93	NUM
admet-520	150	88	1.08	1.08	NUM
admet-520	150	89	0.49	0.49	NUM
admet-520	150	90	n	n	NUM
admet-520	150	91	0.35	0.35	NUM
admet-520	150	92	1.00	1.00	NUM
admet-520	150	93	-0.07	-0.07	NUM
admet-520	150	94	0.55	0.55	NUM
admet-520	150	95	e	e	NOUN
admet-520	150	96	-2.36	-2.36	NOUN
admet-520	150	97	-5.05	-5.05	NOUN
admet-520	150	98	6.41	6.41	NUM
admet-520	150	99	-5.00	-5.00	NOUN
admet-520	150	100	d	d	NOUN
admet-520	150	101	-2.54	-2.54	NOUN
admet-520	150	102	-5.05	-5.05	NOUN
admet-520	150	103	2.83	2.83	NUM
admet-520	150	104	-6.04	-6.04	NUM
admet-520	150	105	the	the	DET
admet-520	150	106	relative	relative	ADJ
admet-520	150	107	changes	change	NOUN
admet-520	150	108	in	in	ADP
admet-520	150	109	retention	retention	NOUN
admet-520	150	110	for	for	ADP
admet-520	150	111	aromatic	aromatic	ADJ
admet-520	150	112	and	and	CCONJ
admet-520	150	113	charged	charge	VERB
admet-520	150	114	residues	residue	NOUN
admet-520	150	115	suggest	suggest	VERB
admet-520	150	116	that	that	SCONJ
admet-520	150	117	the	the	DET
admet-520	150	118	zwitterionic	zwitterionic	ADJ
admet-520	150	119	head	head	NOUN
admet-520	150	120	group	group	NOUN
admet-520	150	121	contributes	contribute	VERB
admet-520	150	122	to	to	ADP
admet-520	150	123	the	the	DET
admet-520	150	124	separation	separation	NOUN
admet-520	150	125	mechanism	mechanism	NOUN
admet-520	150	126	.	.	PUNCT
admet-520	151	1	we	we	PRON
admet-520	151	2	observe	observe	VERB
admet-520	151	3	that	that	SCONJ
admet-520	151	4	the	the	DET
admet-520	151	5	negatively	negatively	ADV
admet-520	151	6	charged	charge	VERB
admet-520	151	7	amino	amino	NOUN
admet-520	151	8	acids	acid	NOUN
admet-520	151	9	asp	asp	PROPN
admet-520	151	10	and	and	CCONJ
admet-520	151	11	glu	glu	NOUN
admet-520	151	12	have	have	VERB
admet-520	151	13	a	a	DET
admet-520	151	14	decreased	decrease	VERB
admet-520	151	15	,	,	PUNCT
admet-520	151	16	and	and	CCONJ
admet-520	151	17	the	the	DET
admet-520	151	18	positively	positively	ADV
admet-520	151	19	charged	charge	VERB
admet-520	151	20	arg	arg	NOUN
admet-520	151	21	and	and	CCONJ
admet-520	151	22	lys	lys	PROPN
admet-520	151	23	have	have	VERB
admet-520	151	24	an	an	DET
admet-520	151	25	increased	increase	VERB
admet-520	151	26	retention	retention	NOUN
admet-520	151	27	on	on	ADP
admet-520	151	28	the	the	DET
admet-520	151	29	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	151	30	compared	compare	VERB
admet-520	151	31	to	to	ADP
admet-520	151	32	c18	c18	NOUN
admet-520	151	33	stationary	stationary	ADJ
admet-520	151	34	phase	phase	NOUN
admet-520	151	35	.	.	PUNCT
admet-520	152	1	this	this	PRON
admet-520	152	2	suggests	suggest	VERB
admet-520	152	3	the	the	DET
admet-520	152	4	involvement	involvement	NOUN
admet-520	152	5	of	of	ADP
admet-520	152	6	electrostatic	electrostatic	ADJ
admet-520	152	7	interactions	interaction	NOUN
admet-520	152	8	(	(	PUNCT
admet-520	152	9	repulsion	repulsion	NOUN
admet-520	152	10	/	/	SYM
admet-520	152	11	attraction	attraction	NOUN
admet-520	152	12	)	)	PUNCT
admet-520	152	13	with	with	ADP
admet-520	152	14	negatively	negatively	ADV
admet-520	152	15	charged	charge	VERB
admet-520	152	16	glycerophosphate	glycerophosphate	NOUN
admet-520	152	17	groups	group	NOUN
admet-520	152	18	.	.	PUNCT
admet-520	153	1	considering	consider	VERB
admet-520	153	2	the	the	DET
admet-520	153	3	behaviour	behaviour	NOUN
admet-520	153	4	of	of	ADP
admet-520	153	5	aromatic	aromatic	ADJ
admet-520	153	6	amino	amino	NOUN
admet-520	153	7	acids	acid	NOUN
admet-520	153	8	(	(	PUNCT
admet-520	153	9	trp	trp	PROPN
admet-520	153	10	,	,	PUNCT
admet-520	153	11	tyr	tyr	PROPN
admet-520	153	12	,	,	PUNCT
admet-520	153	13	his	his	PRON
admet-520	153	14	,	,	PUNCT
admet-520	153	15	and	and	CCONJ
admet-520	153	16	phe	phe	PROPN
admet-520	153	17	)	)	PUNCT
admet-520	153	18	,	,	PUNCT
admet-520	153	19	all	all	PRON
admet-520	153	20	of	of	ADP
admet-520	153	21	which	which	PRON
admet-520	153	22	have	have	VERB
admet-520	153	23	larger	large	ADJ
admet-520	153	24	rc	rc	PROPN
admet-520	153	25	values	value	NOUN
admet-520	153	26	,	,	PUNCT
admet-520	153	27	except	except	SCONJ
admet-520	153	28	for	for	ADP
admet-520	153	29	phe	phe	NOUN
admet-520	153	30	,	,	PUNCT
admet-520	153	31	aromatic	aromatic	ADJ
admet-520	153	32	rings	ring	NOUN
admet-520	153	33	contain	contain	VERB
admet-520	153	34	conjugated	conjugated	ADJ
admet-520	153	35	pi	pi	NOUN
admet-520	153	36	-	-	PUNCT
admet-520	153	37	systems	system	NOUN
admet-520	153	38	,	,	PUNCT
admet-520	153	39	which	which	PRON
admet-520	153	40	possess	possess	VERB
admet-520	153	41	electro	electro	ADJ
admet-520	153	42	-	-	PUNCT
admet-520	153	43	negative	negative	ADJ
admet-520	153	44	character	character	NOUN
admet-520	153	45	.	.	PUNCT
admet-520	154	1	we	we	PRON
admet-520	154	2	have	have	AUX
admet-520	154	3	concluded	conclude	VERB
admet-520	154	4	that	that	SCONJ
admet-520	154	5	the	the	DET
admet-520	154	6	reason	reason	NOUN
admet-520	154	7	these	these	DET
admet-520	154	8	residues	residue	NOUN
admet-520	154	9	increase	increase	VERB
admet-520	154	10	in	in	ADP
admet-520	154	11	retention	retention	NOUN
admet-520	154	12	is	be	AUX
admet-520	154	13	due	due	ADJ
admet-520	154	14	to	to	ADP
admet-520	154	15	their	their	PRON
admet-520	154	16	interaction	interaction	NOUN
admet-520	154	17	with	with	ADP
admet-520	154	18	the	the	DET
admet-520	154	19	phosphate	phosphate	ADJ
admet-520	154	20	group	group	NOUN
admet-520	154	21	.	.	PUNCT
admet-520	155	1	tyr	tyr	PROPN
admet-520	155	2	,	,	PUNCT
admet-520	155	3	trp	trp	PROPN
admet-520	155	4	,	,	PUNCT
admet-520	155	5	and	and	CCONJ
admet-520	155	6	his	his	PRON
admet-520	155	7	all	all	PRON
admet-520	155	8	contain	contain	VERB
admet-520	155	9	nitrogen	nitrogen	NOUN
admet-520	155	10	or	or	CCONJ
admet-520	155	11	oxygen	oxygen	NOUN
admet-520	155	12	bonded	bond	VERB
admet-520	155	13	to	to	ADP
admet-520	155	14	a	a	DET
admet-520	155	15	hydrogen	hydrogen	NOUN
admet-520	155	16	in	in	ADP
admet-520	155	17	their	their	PRON
admet-520	155	18	side	side	NOUN
admet-520	155	19	chains	chain	NOUN
admet-520	155	20	connected	connect	VERB
admet-520	155	21	to	to	ADP
admet-520	155	22	their	their	PRON
admet-520	155	23	aromatic	aromatic	ADJ
admet-520	155	24	rings	ring	NOUN
admet-520	155	25	,	,	PUNCT
admet-520	155	26	while	while	SCONJ
admet-520	155	27	phe	phe	NOUN
admet-520	155	28	does	do	VERB
admet-520	155	29	not	not	PART
admet-520	155	30	.	.	PUNCT
admet-520	156	1	the	the	DET
admet-520	156	2	partial	partial	ADJ
admet-520	156	3	positive	positive	ADJ
admet-520	156	4	charge	charge	NOUN
admet-520	156	5	of	of	ADP
admet-520	156	6	the	the	DET
admet-520	156	7	hydrogen	hydrogen	NOUN
admet-520	156	8	allows	allow	VERB
admet-520	156	9	for	for	SCONJ
admet-520	156	10	a	a	DET
admet-520	156	11	hydrogen	hydrogen	NOUN
admet-520	156	12	bond	bond	NOUN
admet-520	156	13	to	to	PART
admet-520	156	14	form	form	VERB
admet-520	156	15	between	between	ADP
admet-520	156	16	the	the	DET
admet-520	156	17	side	side	NOUN
admet-520	156	18	chain	chain	NOUN
admet-520	156	19	and	and	CCONJ
admet-520	156	20	the	the	DET
admet-520	156	21	phosphate	phosphate	NOUN
admet-520	156	22	.	.	PUNCT
admet-520	157	1	this	this	PRON
admet-520	157	2	,	,	PUNCT
admet-520	157	3	in	in	ADP
admet-520	157	4	turn	turn	NOUN
admet-520	157	5	,	,	PUNCT
admet-520	157	6	delocalizes	delocalize	VERB
admet-520	157	7	the	the	DET
admet-520	157	8	negative	negative	ADJ
admet-520	157	9	charge	charge	NOUN
admet-520	157	10	of	of	ADP
admet-520	157	11	the	the	DET
admet-520	157	12	phosphate	phosphate	NOUN
admet-520	157	13	across	across	ADP
admet-520	157	14	the	the	DET
admet-520	157	15	entire	entire	ADJ
admet-520	157	16	aromatic	aromatic	ADJ
admet-520	157	17	ring	ring	NOUN
admet-520	157	18	.	.	PUNCT
admet-520	158	1	this	this	PRON
admet-520	158	2	is	be	AUX
admet-520	158	3	known	know	VERB
admet-520	158	4	to	to	PART
admet-520	158	5	provide	provide	VERB
admet-520	158	6	a	a	DET
admet-520	158	7	stabilizing	stabilize	VERB
admet-520	158	8	effect	effect	NOUN
admet-520	158	9	and	and	CCONJ
admet-520	158	10	thus	thus	ADV
admet-520	158	11	would	would	AUX
admet-520	158	12	increase	increase	VERB
admet-520	158	13	retention	retention	NOUN
admet-520	158	14	.	.	PUNCT
admet-520	159	1	the	the	DET
admet-520	159	2	inability	inability	NOUN
admet-520	159	3	to	to	PART
admet-520	159	4	form	form	VERB
admet-520	159	5	a	a	DET
admet-520	159	6	hydrogen	hydrogen	NOUN
admet-520	159	7	bond	bond	NOUN
admet-520	159	8	with	with	ADP
admet-520	159	9	phe	phe	PROPN
admet-520	159	10	is	be	AUX
admet-520	159	11	why	why	SCONJ
admet-520	159	12	phe	phe	PROPN
admet-520	159	13	behaves	behave	VERB
admet-520	159	14	like	like	ADP
admet-520	159	15	the	the	DET
admet-520	159	16	other	other	ADJ
admet-520	159	17	hydrophobic	hydrophobic	NOUN
admet-520	159	18	residues	residue	NOUN
admet-520	159	19	and	and	CCONJ
admet-520	159	20	does	do	AUX
admet-520	159	21	not	not	PART
admet-520	159	22	exhibit	exhibit	VERB
admet-520	159	23	an	an	DET
admet-520	159	24	increased	increased	ADJ
admet-520	159	25	contribution	contribution	NOUN
admet-520	159	26	.	.	PUNCT
admet-520	160	1	the	the	DET
admet-520	160	2	delocalization	delocalization	NOUN
admet-520	160	3	effect	effect	NOUN
admet-520	160	4	is	be	AUX
admet-520	160	5	further	far	ADV
admet-520	160	6	supported	support	VERB
admet-520	160	7	by	by	ADP
admet-520	160	8	the	the	DET
admet-520	160	9	relatively	relatively	ADV
admet-520	160	10	large	large	ADJ
admet-520	160	11	increase	increase	NOUN
admet-520	160	12	in	in	ADP
admet-520	160	13	retention	retention	NOUN
admet-520	160	14	of	of	ADP
admet-520	160	15	arg	arg	NOUN
admet-520	160	16	in	in	ADP
admet-520	160	17	comparison	comparison	NOUN
admet-520	160	18	to	to	ADP
admet-520	160	19	lys	lys	PROPN
admet-520	160	20	.	.	PUNCT
admet-520	161	1	although	although	SCONJ
admet-520	161	2	lys	lys	PROPN
admet-520	161	3	and	and	CCONJ
admet-520	161	4	arg	arg	NOUN
admet-520	161	5	have	have	VERB
admet-520	161	6	nearly	nearly	ADV
admet-520	161	7	identical	identical	ADJ
admet-520	161	8	rc	rc	PROPN
admet-520	161	9	’s	’s	NOUN
admet-520	161	10	on	on	ADP
admet-520	161	11	the	the	DET
admet-520	161	12	c18	c18	NOUN
admet-520	161	13	phase	phase	NOUN
admet-520	161	14	,	,	PUNCT
admet-520	161	15	in	in	ADP
admet-520	161	16	the	the	DET
admet-520	161	17	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	161	18	phase	phase	NOUN
admet-520	161	19	,	,	PUNCT
admet-520	161	20	the	the	DET
admet-520	161	21	retention	retention	NOUN
admet-520	161	22	of	of	ADP
admet-520	161	23	arg	arg	NOUN
admet-520	161	24	is	be	AUX
admet-520	161	25	much	much	ADV
admet-520	161	26	greater	great	ADJ
admet-520	161	27	than	than	ADP
admet-520	161	28	lys	lys	PROPN
admet-520	161	29	.	.	PUNCT
admet-520	162	1	this	this	PRON
admet-520	162	2	could	could	AUX
admet-520	162	3	be	be	AUX
admet-520	162	4	explained	explain	VERB
admet-520	162	5	by	by	ADP
admet-520	162	6	the	the	DET
admet-520	162	7	delocalized	delocalize	VERB
admet-520	162	8	positive	positive	ADJ
admet-520	162	9	charge	charge	NOUN
admet-520	162	10	across	across	ADP
admet-520	162	11	the	the	DET
admet-520	162	12	two	two	NUM
admet-520	162	13	amine	amine	ADJ
admet-520	162	14	groups	group	NOUN
admet-520	162	15	interacting	interact	VERB
admet-520	162	16	more	more	ADV
admet-520	162	17	strongly	strongly	ADV
admet-520	162	18	with	with	ADP
admet-520	162	19	the	the	DET
admet-520	162	20	negatively	negatively	ADV
admet-520	162	21	charged	charge	VERB
admet-520	162	22	phosphate	phosphate	NOUN
admet-520	162	23	than	than	ADP
admet-520	162	24	the	the	DET
admet-520	162	25	single	single	ADJ
admet-520	162	26	positively	positively	ADV
admet-520	162	27	charged	charge	VERB
admet-520	162	28	amine	amine	ADJ
admet-520	162	29	group	group	NOUN
admet-520	162	30	of	of	ADP
admet-520	162	31	lys	lys	PROPN
admet-520	162	32	.	.	PUNCT
admet-520	163	1	overall	overall	ADV
admet-520	163	2	,	,	PUNCT
admet-520	163	3	the	the	DET
admet-520	163	4	major	major	ADJ
admet-520	163	5	changes	change	NOUN
admet-520	163	6	in	in	ADP
admet-520	163	7	retention	retention	NOUN
admet-520	163	8	between	between	ADP
admet-520	163	9	the	the	DET
admet-520	163	10	columns	column	NOUN
admet-520	163	11	can	can	AUX
admet-520	163	12	be	be	AUX
admet-520	163	13	explained	explain	VERB
admet-520	163	14	by	by	ADP
admet-520	163	15	the	the	DET
admet-520	163	16	interaction	interaction	NOUN
admet-520	163	17	of	of	ADP
admet-520	163	18	the	the	DET
admet-520	163	19	zwitterionic	zwitterionic	ADJ
admet-520	163	20	head	head	NOUN
admet-520	163	21	groups	group	NOUN
admet-520	163	22	in	in	ADP
admet-520	163	23	addition	addition	NOUN
admet-520	163	24	to	to	ADP
admet-520	163	25	the	the	DET
admet-520	163	26	aliphatic	aliphatic	ADJ
admet-520	163	27	chains	chain	NOUN
admet-520	163	28	that	that	PRON
admet-520	163	29	are	be	AUX
admet-520	163	30	similar	similar	ADJ
admet-520	163	31	to	to	ADP
admet-520	163	32	those	those	PRON
admet-520	163	33	on	on	ADP
admet-520	163	34	oleg	oleg	PROPN
admet-520	163	35	krokhin	krokhin	PROPN
admet-520	163	36	et	et	PROPN
admet-520	163	37	al	al	PROPN
admet-520	163	38	.	.	PROPN
admet-520	163	39	admet	admet	PROPN
admet-520	163	40	&	&	CCONJ
admet-520	163	41	dmpk	dmpk	PROPN
admet-520	163	42	6(2	6(2	NUM
admet-520	163	43	)	)	PUNCT
admet-520	163	44	(	(	PUNCT
admet-520	163	45	2018	2018	NUM
admet-520	163	46	)	)	PUNCT
admet-520	163	47	190	190	NUM
admet-520	163	48	-	-	SYM
admet-520	163	49	199	199	NUM
admet-520	163	50	198	198	NUM
admet-520	163	51	the	the	DET
admet-520	163	52	c18	c18	NOUN
admet-520	163	53	stationary	stationary	ADJ
admet-520	163	54	phase	phase	NOUN
admet-520	163	55	.	.	PUNCT
admet-520	164	1	conclusions	conclusion	NOUN
admet-520	164	2	a	a	DET
admet-520	164	3	peptide	peptide	ADJ
admet-520	164	4	retention	retention	NOUN
admet-520	164	5	prediction	prediction	NOUN
admet-520	164	6	model	model	NOUN
admet-520	164	7	for	for	ADP
admet-520	164	8	reversed	reverse	VERB
admet-520	164	9	-	-	PUNCT
admet-520	164	10	phase	phase	NOUN
admet-520	164	11	separation	separation	NOUN
admet-520	164	12	on	on	ADP
admet-520	164	13	immobilized	immobilized	ADJ
admet-520	164	14	artificial	artificial	ADJ
admet-520	164	15	membrane	membrane	NOUN
admet-520	164	16	phosphatidylcholine	phosphatidylcholine	NOUN
admet-520	164	17	(	(	PUNCT
admet-520	164	18	iam.pc	iam.pc	NOUN
admet-520	164	19	)	)	PUNCT
admet-520	164	20	stationary	stationary	ADJ
admet-520	164	21	phase	phase	NOUN
admet-520	164	22	has	have	AUX
admet-520	164	23	been	be	AUX
admet-520	164	24	developed	develop	VERB
admet-520	164	25	.	.	PUNCT
admet-520	165	1	chromatographic	chromatographic	ADJ
admet-520	165	2	conditions	condition	NOUN
admet-520	165	3	for	for	ADP
admet-520	165	4	highthroughput	highthroughput	ADJ
admet-520	165	5	measurements	measurement	NOUN
admet-520	165	6	of	of	ADP
admet-520	165	7	peptide	peptide	ADJ
admet-520	165	8	retention	retention	NOUN
admet-520	165	9	on	on	ADP
admet-520	165	10	an	an	DET
admet-520	165	11	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	165	12	phase	phase	NOUN
admet-520	165	13	in	in	ADP
admet-520	165	14	reversed	reversed	ADJ
admet-520	165	15	-	-	PUNCT
admet-520	165	16	phase	phase	NOUN
admet-520	165	17	separation	separation	NOUN
admet-520	165	18	mode	mode	NOUN
admet-520	165	19	at	at	ADP
admet-520	165	20	ph	ph	PROPN
admet-520	165	21	7.4	7.4	NUM
admet-520	165	22	have	have	AUX
admet-520	165	23	been	be	AUX
admet-520	165	24	established	establish	VERB
admet-520	165	25	and	and	CCONJ
admet-520	165	26	compared	compare	VERB
admet-520	165	27	to	to	ADP
admet-520	165	28	a	a	DET
admet-520	165	29	standard	standard	ADJ
admet-520	165	30	c18	c18	NOUN
admet-520	165	31	phase	phase	NOUN
admet-520	165	32	.	.	PUNCT
admet-520	166	1	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	166	2	was	be	AUX
admet-520	166	3	found	find	VERB
admet-520	166	4	to	to	PART
admet-520	166	5	be	be	AUX
admet-520	166	6	more	more	ADV
admet-520	166	7	hydrophilic	hydrophilic	ADJ
admet-520	166	8	and	and	CCONJ
admet-520	166	9	to	to	PART
admet-520	166	10	exhibit	exhibit	VERB
admet-520	166	11	lower	low	ADJ
admet-520	166	12	peptide	peptide	NOUN
admet-520	166	13	retention	retention	NOUN
admet-520	166	14	(	(	PUNCT
admet-520	166	15	by	by	ADP
admet-520	166	16	~14	~14	NOUN
admet-520	166	17	%	%	NOUN
admet-520	166	18	acetonitrile	acetonitrile	NOUN
admet-520	166	19	on	on	ADP
admet-520	166	20	average	average	ADJ
admet-520	166	21	,	,	PUNCT
admet-520	166	22	calculated	calculate	VERB
admet-520	166	23	for	for	ADP
admet-520	166	24	all	all	DET
admet-520	166	25	s.cerevisiae	s.cerevisiae	ADJ
admet-520	166	26	peptides	peptide	NOUN
admet-520	166	27	retained	retain	VERB
admet-520	166	28	in	in	ADP
admet-520	166	29	both	both	DET
admet-520	166	30	systems	system	NOUN
admet-520	166	31	)	)	PUNCT
admet-520	166	32	compared	compare	VERB
admet-520	166	33	to	to	ADP
admet-520	166	34	octadecyl	octadecyl	NOUN
admet-520	166	35	-	-	PUNCT
admet-520	166	36	silica	silica	NOUN
admet-520	166	37	(	(	PUNCT
admet-520	166	38	c18	c18	NOUN
admet-520	166	39	)	)	PUNCT
admet-520	166	40	.	.	PUNCT
admet-520	167	1	2d	2d	PROPN
admet-520	167	2	lc	lc	PROPN
admet-520	167	3	-	-	PUNCT
admet-520	167	4	ms	ms	PROPN
admet-520	167	5	/	/	SYM
admet-520	167	6	ms	ms	NOUN
admet-520	167	7	analysis	analysis	NOUN
admet-520	167	8	of	of	ADP
admet-520	167	9	a	a	DET
admet-520	167	10	complex	complex	ADJ
admet-520	167	11	s.	s.	PROPN
admet-520	167	12	cerevisiae	cerevisiae	PROPN
admet-520	167	13	digest	digest	VERB
admet-520	167	14	with	with	ADP
admet-520	167	15	iam.pc	iam.pc	PROPN
admet-520	167	16	or	or	CCONJ
admet-520	167	17	c18	c18	NOUN
admet-520	167	18	columns	column	NOUN
admet-520	167	19	in	in	ADP
admet-520	167	20	the	the	DET
admet-520	167	21	first	first	ADJ
admet-520	167	22	dimension	dimension	NOUN
admet-520	167	23	allowed	allow	VERB
admet-520	167	24	the	the	DET
admet-520	167	25	measurement	measurement	NOUN
admet-520	167	26	of	of	ADP
admet-520	167	27	the	the	DET
admet-520	167	28	retention	retention	NOUN
admet-520	167	29	properties	property	NOUN
admet-520	167	30	of	of	ADP
admet-520	167	31	tens	ten	NOUN
admet-520	167	32	of	of	ADP
admet-520	167	33	thousands	thousand	NOUN
admet-520	167	34	of	of	ADP
admet-520	167	35	peptides	peptide	NOUN
admet-520	167	36	–	–	PUNCT
admet-520	167	37	sufficient	sufficient	ADJ
admet-520	167	38	for	for	ADP
admet-520	167	39	the	the	DET
admet-520	167	40	confident	confident	ADJ
admet-520	167	41	assignment	assignment	NOUN
admet-520	167	42	of	of	ADP
admet-520	167	43	retention	retention	NOUN
admet-520	167	44	coefficients	coefficient	NOUN
admet-520	167	45	and	and	CCONJ
admet-520	167	46	the	the	DET
admet-520	167	47	development	development	NOUN
admet-520	167	48	of	of	ADP
admet-520	167	49	a	a	DET
admet-520	167	50	sequence	sequence	NOUN
admet-520	167	51	-	-	PUNCT
admet-520	167	52	specific	specific	ADJ
admet-520	167	53	prediction	prediction	NOUN
admet-520	167	54	algorithm	algorithm	NOUN
admet-520	167	55	.	.	PUNCT
admet-520	168	1	peptide	peptide	ADJ
admet-520	168	2	retention	retention	NOUN
admet-520	168	3	on	on	ADP
admet-520	168	4	the	the	DET
admet-520	168	5	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	168	6	phase	phase	NOUN
admet-520	168	7	is	be	AUX
admet-520	168	8	driven	drive	VERB
admet-520	168	9	by	by	ADP
admet-520	168	10	hydrophobic	hydrophobic	NOUN
admet-520	168	11	interactions	interaction	NOUN
admet-520	168	12	.	.	PUNCT
admet-520	169	1	however	however	ADV
admet-520	169	2	,	,	PUNCT
admet-520	169	3	we	we	PRON
admet-520	169	4	found	find	VERB
admet-520	169	5	a	a	DET
admet-520	169	6	substantial	substantial	ADJ
admet-520	169	7	increase	increase	NOUN
admet-520	169	8	in	in	ADP
admet-520	169	9	the	the	DET
admet-520	169	10	relative	relative	ADJ
admet-520	169	11	retention	retention	NOUN
admet-520	169	12	contribution	contribution	NOUN
admet-520	169	13	(	(	PUNCT
admet-520	169	14	compared	compare	VERB
admet-520	169	15	to	to	ADP
admet-520	169	16	c18	c18	NOUN
admet-520	169	17	)	)	PUNCT
admet-520	169	18	for	for	ADP
admet-520	169	19	positively	positively	ADV
admet-520	169	20	charged	charge	VERB
admet-520	169	21	(	(	PUNCT
admet-520	169	22	arg	arg	NOUN
admet-520	169	23	and	and	CCONJ
admet-520	169	24	lys	lys	PROPN
admet-520	169	25	)	)	PUNCT
admet-520	169	26	and	and	CCONJ
admet-520	169	27	aromatic	aromatic	ADJ
admet-520	169	28	(	(	PUNCT
admet-520	169	29	tyr	tyr	PROPN
admet-520	169	30	,	,	PUNCT
admet-520	169	31	trp	trp	PROPN
admet-520	169	32	and	and	CCONJ
admet-520	169	33	his	his	PRON
admet-520	169	34	)	)	PUNCT
admet-520	169	35	residues	residue	NOUN
admet-520	169	36	,	,	PUNCT
admet-520	169	37	and	and	CCONJ
admet-520	169	38	a	a	DET
admet-520	169	39	decrease	decrease	NOUN
admet-520	169	40	for	for	ADP
admet-520	169	41	negatively	negatively	ADV
admet-520	169	42	charged	charge	VERB
admet-520	169	43	(	(	PUNCT
admet-520	169	44	asp	asp	PROPN
admet-520	169	45	and	and	CCONJ
admet-520	169	46	glu	glu	NOUN
admet-520	169	47	)	)	PUNCT
admet-520	169	48	residues	residue	NOUN
admet-520	169	49	compared	compare	VERB
admet-520	169	50	to	to	ADP
admet-520	169	51	c18	c18	NOUN
admet-520	169	52	.	.	PUNCT
admet-520	170	1	this	this	PRON
admet-520	170	2	indicated	indicate	VERB
admet-520	170	3	the	the	DET
admet-520	170	4	involvement	involvement	NOUN
admet-520	170	5	of	of	ADP
admet-520	170	6	other	other	ADJ
admet-520	170	7	types	type	NOUN
admet-520	170	8	of	of	ADP
admet-520	170	9	interactions	interaction	NOUN
admet-520	170	10	(	(	PUNCT
admet-520	170	11	electrostatic	electrostatic	ADJ
admet-520	170	12	and	and	CCONJ
admet-520	170	13	electron	electron	NOUN
admet-520	170	14	delocalization	delocalization	NOUN
admet-520	170	15	)	)	PUNCT
admet-520	170	16	,	,	PUNCT
admet-520	170	17	which	which	PRON
admet-520	170	18	results	result	VERB
admet-520	170	19	in	in	ADP
admet-520	170	20	a	a	DET
admet-520	170	21	mixed	mixed	ADJ
admet-520	170	22	-	-	PUNCT
admet-520	170	23	mode	mode	NOUN
admet-520	170	24	retention	retention	NOUN
admet-520	170	25	mechanism	mechanism	NOUN
admet-520	170	26	.	.	PUNCT
admet-520	171	1	due	due	ADP
admet-520	171	2	to	to	ADP
admet-520	171	3	the	the	DET
admet-520	171	4	lower	low	ADJ
admet-520	171	5	overall	overall	ADJ
admet-520	171	6	hydrophobicity	hydrophobicity	NOUN
admet-520	171	7	of	of	ADP
admet-520	171	8	the	the	DET
admet-520	171	9	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	171	10	stationary	stationary	ADJ
admet-520	171	11	phase	phase	NOUN
admet-520	171	12	,	,	PUNCT
admet-520	171	13	the	the	DET
admet-520	171	14	effect	effect	NOUN
admet-520	171	15	of	of	ADP
admet-520	171	16	amphipathic	amphipathic	ADJ
admet-520	171	17	helicity	helicity	NOUN
admet-520	171	18	on	on	ADP
admet-520	171	19	retention	retention	NOUN
admet-520	171	20	is	be	AUX
admet-520	171	21	less	less	ADV
admet-520	171	22	profound	profound	ADJ
admet-520	171	23	.	.	PUNCT
admet-520	172	1	at	at	ADP
admet-520	172	2	the	the	DET
admet-520	172	3	same	same	ADJ
admet-520	172	4	time	time	NOUN
admet-520	172	5	,	,	PUNCT
admet-520	172	6	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	172	7	version	version	NOUN
admet-520	172	8	of	of	ADP
admet-520	172	9	the	the	DET
admet-520	172	10	ssrcalc	ssrcalc	ADJ
admet-520	172	11	algorithm	algorithm	NOUN
admet-520	172	12	showed	show	VERB
admet-520	172	13	a	a	DET
admet-520	172	14	lower	low	ADJ
admet-520	172	15	accuracy	accuracy	NOUN
admet-520	172	16	compared	compare	VERB
admet-520	172	17	to	to	ADP
admet-520	172	18	c18	c18	PROPN
admet-520	172	19	version	version	NOUN
admet-520	172	20	,	,	PUNCT
admet-520	172	21	suggesting	suggest	VERB
admet-520	172	22	that	that	SCONJ
admet-520	172	23	additional	additional	ADJ
admet-520	172	24	sequence	sequence	NOUN
admet-520	172	25	-	-	PUNCT
admet-520	172	26	specific	specific	ADJ
admet-520	172	27	features	feature	NOUN
admet-520	172	28	(	(	PUNCT
admet-520	172	29	yet	yet	ADV
admet-520	172	30	to	to	PART
admet-520	172	31	be	be	AUX
admet-520	172	32	discovered	discover	VERB
admet-520	172	33	)	)	PUNCT
admet-520	172	34	play	play	VERB
admet-520	172	35	a	a	DET
admet-520	172	36	role	role	NOUN
admet-520	172	37	in	in	ADP
admet-520	172	38	peptide	peptide	ADJ
admet-520	172	39	separation	separation	NOUN
admet-520	172	40	on	on	ADP
admet-520	172	41	the	the	DET
admet-520	172	42	phosphatidylcholine	phosphatidylcholine	NOUN
admet-520	172	43	stationary	stationary	ADJ
admet-520	172	44	phase	phase	NOUN
admet-520	172	45	.	.	PUNCT
admet-520	173	1	acknowledgements	acknowledgement	NOUN
admet-520	173	2	:	:	PUNCT
admet-520	173	3	this	this	DET
admet-520	173	4	work	work	NOUN
admet-520	173	5	was	be	AUX
admet-520	173	6	supported	support	VERB
admet-520	173	7	by	by	ADP
admet-520	173	8	a	a	DET
admet-520	173	9	grant	grant	NOUN
admet-520	173	10	from	from	ADP
admet-520	173	11	the	the	DET
admet-520	173	12	natural	natural	ADJ
admet-520	173	13	sciences	science	NOUN
admet-520	173	14	and	and	CCONJ
admet-520	173	15	engineering	engineering	NOUN
admet-520	173	16	research	research	NOUN
admet-520	173	17	council	council	PROPN
admet-520	173	18	of	of	ADP
admet-520	173	19	canada	canada	PROPN
admet-520	173	20	(	(	PUNCT
admet-520	173	21	rgpin-2016	rgpin-2016	PROPN
admet-520	173	22	-	-	PUNCT
admet-520	173	23	05963	05963	NUM
admet-520	173	24	;	;	PUNCT
admet-520	173	25	o.v.k	o.v.k	ADJ
admet-520	173	26	.	.	PUNCT
admet-520	173	27	)	)	PUNCT
admet-520	173	28	.	.	PUNCT
admet-520	174	1	the	the	DET
admet-520	174	2	authors	author	NOUN
admet-520	174	3	also	also	ADV
admet-520	174	4	wish	wish	VERB
admet-520	174	5	to	to	PART
admet-520	174	6	thank	thank	VERB
admet-520	174	7	scott	scott	PROPN
admet-520	174	8	anderson	anderson	PROPN
admet-520	174	9	and	and	CCONJ
admet-520	174	10	melissa	melissa	PROPN
admet-520	174	11	wilcox	wilcox	PROPN
admet-520	174	12	from	from	ADP
admet-520	174	13	regis	regis	PROPN
admet-520	174	14	technologies	technologies	PROPN
admet-520	174	15	,	,	PUNCT
admet-520	174	16	inc	inc	PROPN
admet-520	174	17	.	.	PROPN
admet-520	174	18	for	for	ADP
admet-520	174	19	providing	provide	VERB
admet-520	174	20	the	the	DET
admet-520	174	21	iam.pc.dd2	iam.pc.dd2	PROPN
admet-520	174	22	packing	packing	NOUN
admet-520	174	23	material	material	NOUN
admet-520	174	24	.	.	PUNCT
admet-520	175	1	references	reference	NOUN
admet-520	175	2	[	[	X
admet-520	175	3	1	1	NUM
admet-520	175	4	]	]	X
admet-520	175	5	j.m	j.m	PROPN
admet-520	175	6	.	.	PROPN
admet-520	175	7	parker	parker	PROPN
admet-520	175	8	,	,	PUNCT
admet-520	175	9	d.	d.	PROPN
admet-520	175	10	guo	guo	PROPN
admet-520	175	11	,	,	PUNCT
admet-520	175	12	r.s	r.s	PROPN
admet-520	175	13	.	.	PROPN
admet-520	175	14	hodges	hodges	PROPN
admet-520	175	15	.	.	PUNCT
admet-520	176	1	new	new	ADJ
admet-520	176	2	hydrophilicity	hydrophilicity	NOUN
admet-520	176	3	scale	scale	NOUN
admet-520	176	4	derived	derive	VERB
admet-520	176	5	from	from	ADP
admet-520	176	6	high	high	ADJ
admet-520	176	7	-	-	PUNCT
admet-520	176	8	performance	performance	NOUN
admet-520	176	9	liquid	liquid	ADJ
admet-520	176	10	chromatography	chromatography	NOUN
admet-520	176	11	peptide	peptide	NOUN
admet-520	176	12	retention	retention	NOUN
admet-520	176	13	data	datum	NOUN
admet-520	176	14	:	:	PUNCT
admet-520	176	15	correlation	correlation	NOUN
admet-520	176	16	of	of	ADP
admet-520	176	17	predicted	predict	VERB
admet-520	176	18	surface	surface	NOUN
admet-520	176	19	residues	residue	NOUN
admet-520	176	20	with	with	ADP
admet-520	176	21	antigenicity	antigenicity	NOUN
admet-520	176	22	and	and	CCONJ
admet-520	176	23	x	x	NOUN
admet-520	176	24	-	-	NOUN
admet-520	176	25	ray	ray	NOUN
admet-520	176	26	-	-	PUNCT
admet-520	176	27	derived	derive	VERB
admet-520	176	28	accessible	accessible	ADJ
admet-520	176	29	sites	site	NOUN
admet-520	176	30	.	.	PUNCT
admet-520	177	1	biochemistry	biochemistry	NOUN
admet-520	177	2	25	25	NUM
admet-520	177	3	(	(	PUNCT
admet-520	177	4	1986	1986	NUM
admet-520	177	5	)	)	PUNCT
admet-520	177	6	5425	5425	NUM
admet-520	177	7	-	-	SYM
admet-520	177	8	5432	5432	NUM
admet-520	177	9	.	.	PUNCT
admet-520	178	1	[	[	X
admet-520	178	2	2	2	X
admet-520	178	3	]	]	PUNCT
admet-520	178	4	j.	j.	PROPN
admet-520	178	5	kyte	kyte	PROPN
admet-520	178	6	,	,	PUNCT
admet-520	178	7	r.f	r.f	PROPN
admet-520	178	8	.	.	PROPN
admet-520	178	9	doolittle	doolittle	PROPN
admet-520	178	10	.	.	PUNCT
admet-520	179	1	a	a	DET
admet-520	179	2	simple	simple	ADJ
admet-520	179	3	method	method	NOUN
admet-520	179	4	for	for	ADP
admet-520	179	5	displaying	display	VERB
admet-520	179	6	the	the	DET
admet-520	179	7	hydropathic	hydropathic	ADJ
admet-520	179	8	character	character	NOUN
admet-520	179	9	of	of	ADP
admet-520	179	10	a	a	DET
admet-520	179	11	protein	protein	NOUN
admet-520	179	12	.	.	PUNCT
admet-520	180	1	j	j	PROPN
admet-520	180	2	mol	mol	ADP
admet-520	180	3	biol	biol	PROPN
admet-520	180	4	157	157	NUM
admet-520	180	5	(	(	PUNCT
admet-520	180	6	1982	1982	NUM
admet-520	180	7	)	)	PUNCT
admet-520	180	8	105	105	NUM
admet-520	180	9	-	-	SYM
admet-520	180	10	132	132	NUM
admet-520	180	11	.	.	PUNCT
admet-520	181	1	[	[	X
admet-520	181	2	3	3	X
admet-520	181	3	]	]	X
admet-520	181	4	k.l	k.l	PROPN
admet-520	181	5	.	.	PROPN
admet-520	181	6	valko	valko	PROPN
admet-520	181	7	.	.	PUNCT
admet-520	182	1	lipophilicity	lipophilicity	PROPN
admet-520	182	2	and	and	CCONJ
admet-520	182	3	biomimetic	biomimetic	ADJ
admet-520	182	4	properties	property	NOUN
admet-520	182	5	measured	measure	VERB
admet-520	182	6	by	by	ADP
admet-520	182	7	hplc	hplc	NOUN
admet-520	182	8	to	to	PART
admet-520	182	9	support	support	VERB
admet-520	182	10	drug	drug	NOUN
admet-520	182	11	discovery	discovery	NOUN
admet-520	182	12	.	.	PUNCT
admet-520	183	1	j	j	PROPN
admet-520	183	2	pharm	pharm	PROPN
admet-520	183	3	biomed	biome	VERB
admet-520	183	4	anal	anal	ADJ
admet-520	183	5	130	130	NUM
admet-520	183	6	(	(	PUNCT
admet-520	183	7	2016	2016	NUM
admet-520	183	8	)	)	PUNCT
admet-520	183	9	35	35	NUM
admet-520	183	10	-	-	SYM
admet-520	183	11	54	54	NUM
admet-520	183	12	.	.	PUNCT
admet-520	184	1	[	[	X
admet-520	184	2	4	4	NUM
admet-520	184	3	]	]	X
admet-520	184	4	c.	c.	NOUN
admet-520	184	5	pidgeon	pidgeon	PROPN
admet-520	184	6	,	,	PUNCT
admet-520	184	7	s.	s.	PROPN
admet-520	184	8	ong	ong	PROPN
admet-520	184	9	,	,	PUNCT
admet-520	184	10	h.	h.	PROPN
admet-520	184	11	liu	liu	PROPN
admet-520	184	12	,	,	PUNCT
admet-520	184	13	x.	x.	PROPN
admet-520	184	14	qiu	qiu	PROPN
admet-520	184	15	,	,	PUNCT
admet-520	184	16	m.	m.	NOUN
admet-520	184	17	pidgeon	pidgeon	NOUN
admet-520	184	18	,	,	PUNCT
admet-520	184	19	a.h	a.h	PROPN
admet-520	184	20	.	.	PROPN
admet-520	184	21	dantzig	dantzig	PROPN
admet-520	184	22	,	,	PUNCT
admet-520	184	23	j.	j.	PROPN
admet-520	184	24	munroe	munroe	PROPN
admet-520	184	25	,	,	PUNCT
admet-520	184	26	w.j	w.j	PROPN
admet-520	184	27	.	.	PROPN
admet-520	184	28	hornback	hornback	PROPN
admet-520	184	29	,	,	PUNCT
admet-520	184	30	j.s	j.s	PROPN
admet-520	184	31	.	.	PROPN
admet-520	184	32	kasher	kasher	PROPN
admet-520	184	33	,	,	PUNCT
admet-520	184	34	l.	l.	PROPN
admet-520	184	35	glunz	glunz	PROPN
admet-520	184	36	,	,	PUNCT
admet-520	184	37	et	et	PROPN
admet-520	185	1	al	al	PROPN
admet-520	185	2	.	.	PUNCT
admet-520	186	1	iam	iam	PROPN
admet-520	186	2	chromatography	chromatography	NOUN
admet-520	186	3	:	:	PUNCT
admet-520	186	4	an	an	DET
admet-520	186	5	in	in	ADP
admet-520	186	6	vitro	vitro	X
admet-520	186	7	screen	screen	NOUN
admet-520	186	8	for	for	ADP
admet-520	186	9	predicting	predict	VERB
admet-520	186	10	drug	drug	NOUN
admet-520	186	11	membrane	membrane	NOUN
admet-520	186	12	permeability	permeability	NOUN
admet-520	186	13	.	.	PUNCT
admet-520	187	1	j	j	PROPN
admet-520	187	2	med	med	PROPN
admet-520	187	3	chem	chem	NOUN
admet-520	187	4	38	38	NUM
admet-520	187	5	(	(	PUNCT
admet-520	187	6	1995	1995	NUM
admet-520	187	7	)	)	PUNCT
admet-520	187	8	590	590	NUM
admet-520	187	9	-	-	SYM
admet-520	187	10	594	594	NUM
admet-520	187	11	.	.	PUNCT
admet-520	188	1	[	[	X
admet-520	188	2	5	5	NUM
admet-520	188	3	]	]	X
admet-520	188	4	k.m	k.m	PROPN
admet-520	188	5	.	.	PROPN
admet-520	188	6	biswas	biswas	PROPN
admet-520	188	7	,	,	PUNCT
admet-520	188	8	d.r	d.r	PROPN
admet-520	188	9	.	.	PROPN
admet-520	188	10	devido	devido	PROPN
admet-520	188	11	,	,	PUNCT
admet-520	188	12	j.g	j.g	PROPN
admet-520	188	13	.	.	PROPN
admet-520	188	14	dorsey	dorsey	PROPN
admet-520	188	15	.	.	PUNCT
admet-520	189	1	evaluation	evaluation	NOUN
admet-520	189	2	of	of	ADP
admet-520	189	3	methods	method	NOUN
admet-520	189	4	for	for	ADP
admet-520	189	5	measuring	measure	VERB
admet-520	189	6	amino	amino	NOUN
admet-520	189	7	acid	acid	NOUN
admet-520	189	8	hydrophobicities	hydrophobicity	NOUN
admet-520	189	9	and	and	CCONJ
admet-520	189	10	interactions	interaction	NOUN
admet-520	189	11	.	.	PUNCT
admet-520	190	1	j	j	PROPN
admet-520	190	2	chromatogr	chromatogr	VERB
admet-520	190	3	a	a	PRON
admet-520	190	4	1000	1000	NUM
admet-520	190	5	(	(	PUNCT
admet-520	190	6	2003	2003	NUM
admet-520	190	7	)	)	PUNCT
admet-520	190	8	637	637	NUM
admet-520	190	9	-	-	SYM
admet-520	190	10	655	655	NUM
admet-520	190	11	.	.	PUNCT
admet-520	191	1	[	[	X
admet-520	191	2	6	6	NUM
admet-520	191	3	]	]	X
admet-520	191	4	s.e	s.e	PROPN
admet-520	191	5	.	.	PROPN
admet-520	191	6	blondelle	blondelle	PROPN
admet-520	191	7	,	,	PUNCT
admet-520	191	8	e.	e.	PROPN
admet-520	191	9	perez	perez	PROPN
admet-520	191	10	-	-	PUNCT
admet-520	191	11	paya	paya	PROPN
admet-520	191	12	,	,	PUNCT
admet-520	191	13	g.	g.	PROPN
admet-520	191	14	allicotti	allicotti	PROPN
admet-520	191	15	,	,	PUNCT
admet-520	191	16	b.	b.	PROPN
admet-520	191	17	forood	forood	PROPN
admet-520	191	18	,	,	PUNCT
admet-520	191	19	r.a	r.a	PROPN
admet-520	191	20	.	.	PROPN
admet-520	191	21	houghten	houghten	PROPN
admet-520	191	22	.	.	PUNCT
admet-520	192	1	peptide	peptide	ADJ
admet-520	192	2	binding	bind	VERB
admet-520	192	3	domains	domain	NOUN
admet-520	192	4	determined	determine	VERB
admet-520	192	5	through	through	ADP
admet-520	192	6	chemical	chemical	ADJ
admet-520	192	7	modification	modification	NOUN
admet-520	192	8	of	of	ADP
admet-520	192	9	the	the	DET
admet-520	192	10	side	side	NOUN
admet-520	192	11	-	-	PUNCT
admet-520	192	12	chain	chain	NOUN
admet-520	192	13	functional	functional	ADJ
admet-520	192	14	groups	group	NOUN
admet-520	192	15	.	.	PUNCT
admet-520	193	1	biophys	biophy	NOUN
admet-520	193	2	j	j	PROPN
admet-520	193	3	69	69	NUM
admet-520	193	4	(	(	PUNCT
admet-520	193	5	1995	1995	NUM
admet-520	193	6	)	)	PUNCT
admet-520	193	7	604	604	NUM
admet-520	193	8	-	-	SYM
admet-520	193	9	611	611	NUM
admet-520	193	10	.	.	PUNCT
admet-520	194	1	[	[	X
admet-520	194	2	7	7	X
admet-520	194	3	]	]	PUNCT
admet-520	194	4	k.	k.	PROPN
admet-520	194	5	buttner	buttner	PROPN
admet-520	194	6	,	,	PUNCT
admet-520	194	7	s.e	s.e	PROPN
admet-520	194	8	.	.	PROPN
admet-520	194	9	blondelle	blondelle	PROPN
admet-520	194	10	,	,	PUNCT
admet-520	194	11	j.m	j.m	PROPN
admet-520	194	12	.	.	PROPN
admet-520	194	13	ostresh	ostresh	PROPN
admet-520	194	14	,	,	PUNCT
admet-520	194	15	r.a	r.a	PROPN
admet-520	194	16	.	.	PROPN
admet-520	194	17	houghten	houghten	PROPN
admet-520	194	18	.	.	PUNCT
admet-520	195	1	perturbation	perturbation	NOUN
admet-520	195	2	of	of	ADP
admet-520	195	3	peptide	peptide	ADJ
admet-520	195	4	conformations	conformation	NOUN
admet-520	195	5	induced	induce	VERB
admet-520	195	6	in	in	ADP
admet-520	195	7	anisotropic	anisotropic	NOUN
admet-520	195	8	environments	environment	NOUN
admet-520	195	9	.	.	PUNCT
admet-520	196	1	biopolymers	biopolymer	NOUN
admet-520	196	2	32	32	NUM
admet-520	196	3	(	(	PUNCT
admet-520	196	4	1992	1992	NUM
admet-520	196	5	)	)	PUNCT
admet-520	196	6	575	575	NUM
admet-520	196	7	-	-	SYM
admet-520	196	8	583	583	NUM
admet-520	196	9	.	.	PUNCT
admet-520	197	1	[	[	X
admet-520	197	2	8	8	NUM
admet-520	197	3	]	]	X
admet-520	197	4	s.e	s.e	PROPN
admet-520	197	5	.	.	PROPN
admet-520	197	6	blondelle	blondelle	PROPN
admet-520	197	7	,	,	PUNCT
admet-520	197	8	j.m	j.m	PROPN
admet-520	197	9	.	.	PROPN
admet-520	197	10	ostresh	ostresh	PROPN
admet-520	197	11	,	,	PUNCT
admet-520	197	12	r.a	r.a	PROPN
admet-520	197	13	.	.	PROPN
admet-520	197	14	houghten	houghten	PROPN
admet-520	197	15	,	,	PUNCT
admet-520	197	16	e.	e.	PROPN
admet-520	197	17	perez	perez	PROPN
admet-520	197	18	-	-	PUNCT
admet-520	197	19	paya	paya	PROPN
admet-520	197	20	.	.	PUNCT
admet-520	198	1	induced	induce	VERB
admet-520	198	2	conformational	conformational	ADJ
admet-520	198	3	states	state	NOUN
admet-520	198	4	of	of	ADP
admet-520	198	5	amphipathic	amphipathic	ADJ
admet-520	198	6	peptides	peptide	NOUN
admet-520	198	7	in	in	ADP
admet-520	198	8	aqueous	aqueous	ADJ
admet-520	198	9	/	/	SYM
admet-520	198	10	lipid	lipid	NOUN
admet-520	198	11	environments	environment	NOUN
admet-520	198	12	.	.	PUNCT
admet-520	199	1	biophys	biophy	NOUN
admet-520	199	2	j	j	PROPN
admet-520	199	3	68	68	NUM
admet-520	199	4	(	(	PUNCT
admet-520	199	5	1995	1995	NUM
admet-520	199	6	)	)	PUNCT
admet-520	199	7	351	351	NUM
admet-520	199	8	-	-	SYM
admet-520	199	9	359	359	NUM
admet-520	199	10	.	.	PUNCT
admet-520	200	1	admet	admet	PROPN
admet-520	200	2	&	&	CCONJ
admet-520	200	3	dmpk	dmpk	PROPN
admet-520	200	4	6(2	6(2	NUM
admet-520	200	5	)	)	PUNCT
admet-520	200	6	(	(	PUNCT
admet-520	200	7	2018	2018	NUM
admet-520	200	8	)	)	PUNCT
admet-520	200	9	190	190	NUM
admet-520	200	10	-	-	SYM
admet-520	200	11	199	199	NUM
admet-520	200	12	peptide	peptide	NOUN
admet-520	200	13	retention	retention	NOUN
admet-520	200	14	time	time	NOUN
admet-520	200	15	prediction	prediction	NOUN
admet-520	200	16	for	for	ADP
admet-520	200	17	iam.pc	iam.pc	PROPN
admet-520	200	18	stationary	stationary	ADJ
admet-520	200	19	phases	phase	NOUN
admet-520	200	20	doi	doi	NOUN
admet-520	200	21	:	:	PUNCT
admet-520	200	22	10.5599	10.5599	NUM
admet-520	200	23	/	/	SYM
admet-520	200	24	admet.520	admet.520	NOUN
admet-520	200	25	199	199	NUM
admet-520	200	26	[	[	X
admet-520	200	27	9	9	NUM
admet-520	200	28	]	]	X
admet-520	200	29	t.j	t.j	PROPN
admet-520	200	30	.	.	PROPN
admet-520	200	31	sereda	sereda	PROPN
admet-520	200	32	,	,	PUNCT
admet-520	200	33	c.t	c.t	PROPN
admet-520	200	34	.	.	PROPN
admet-520	200	35	mant	mant	PROPN
admet-520	200	36	,	,	PUNCT
admet-520	200	37	r.s	r.s	PROPN
admet-520	200	38	.	.	PROPN
admet-520	200	39	hodges	hodges	PROPN
admet-520	200	40	.	.	PUNCT
admet-520	201	1	selectivity	selectivity	NOUN
admet-520	201	2	due	due	ADP
admet-520	201	3	to	to	ADP
admet-520	201	4	conformational	conformational	ADJ
admet-520	201	5	differences	difference	NOUN
admet-520	201	6	between	between	ADP
admet-520	201	7	helical	helical	ADJ
admet-520	201	8	and	and	CCONJ
admet-520	201	9	non	non	ADJ
admet-520	201	10	-	-	ADJ
admet-520	201	11	helical	helical	ADJ
admet-520	201	12	peptides	peptide	NOUN
admet-520	201	13	in	in	ADP
admet-520	201	14	reversed	reverse	VERB
admet-520	201	15	-	-	PUNCT
admet-520	201	16	phase	phase	NOUN
admet-520	201	17	chromatography	chromatography	NOUN
admet-520	201	18	.	.	PUNCT
admet-520	202	1	j	j	PROPN
admet-520	202	2	chromatogr	chromatogr	VERB
admet-520	202	3	a	a	DET
admet-520	202	4	695	695	NUM
admet-520	202	5	(	(	PUNCT
admet-520	202	6	1995	1995	NUM
admet-520	202	7	)	)	PUNCT
admet-520	202	8	205	205	NUM
admet-520	202	9	-	-	SYM
admet-520	202	10	221	221	NUM
admet-520	202	11	.	.	PUNCT
admet-520	203	1	[	[	X
admet-520	203	2	10	10	NUM
admet-520	203	3	]	]	X
admet-520	203	4	y.	y.	PROPN
admet-520	203	5	chen	chen	PROPN
admet-520	203	6	,	,	PUNCT
admet-520	203	7	c.t	c.t	PROPN
admet-520	203	8	.	.	PROPN
admet-520	203	9	mant	mant	PROPN
admet-520	203	10	,	,	PUNCT
admet-520	203	11	r.s	r.s	PROPN
admet-520	203	12	.	.	PROPN
admet-520	203	13	hodges	hodges	PROPN
admet-520	203	14	.	.	PUNCT
admet-520	204	1	temperature	temperature	NOUN
admet-520	204	2	selectivity	selectivity	NOUN
admet-520	204	3	effects	effect	NOUN
admet-520	204	4	in	in	ADP
admet-520	204	5	reversed	reverse	VERB
admet-520	204	6	-	-	PUNCT
admet-520	204	7	phase	phase	NOUN
admet-520	204	8	liquid	liquid	ADJ
admet-520	204	9	chromatography	chromatography	NOUN
admet-520	204	10	due	due	ADP
admet-520	204	11	to	to	ADP
admet-520	204	12	conformation	conformation	NOUN
admet-520	204	13	differences	difference	NOUN
admet-520	204	14	between	between	ADP
admet-520	204	15	helical	helical	ADJ
admet-520	204	16	and	and	CCONJ
admet-520	204	17	non	non	ADJ
admet-520	204	18	-	-	ADJ
admet-520	204	19	helical	helical	ADJ
admet-520	204	20	peptides	peptide	NOUN
admet-520	204	21	.	.	PUNCT
admet-520	205	1	j	j	PROPN
admet-520	205	2	chromatogr	chromatogr	VERB
admet-520	205	3	a	a	DET
admet-520	205	4	1010	1010	NUM
admet-520	205	5	(	(	PUNCT
admet-520	205	6	2003	2003	NUM
admet-520	205	7	)	)	PUNCT
admet-520	205	8	45	45	NUM
admet-520	205	9	-	-	SYM
admet-520	205	10	61	61	NUM
admet-520	205	11	.	.	PUNCT
admet-520	206	1	[	[	X
admet-520	206	2	11	11	NUM
admet-520	206	3	]	]	PUNCT
admet-520	206	4	z.	z.	PROPN
admet-520	206	5	jiang	jiang	PROPN
admet-520	206	6	,	,	PUNCT
admet-520	206	7	b.j	b.j	PROPN
admet-520	206	8	.	.	PROPN
admet-520	206	9	kullberg	kullberg	PROPN
admet-520	206	10	,	,	PUNCT
admet-520	206	11	h.	h.	PROPN
admet-520	206	12	van	van	PROPN
admet-520	206	13	der	der	PROPN
admet-520	206	14	lee	lee	PROPN
admet-520	206	15	,	,	PUNCT
admet-520	206	16	a.i	a.i	PROPN
admet-520	206	17	.	.	PROPN
admet-520	206	18	vasil	vasil	PROPN
admet-520	206	19	,	,	PUNCT
admet-520	206	20	j.d	j.d	PROPN
admet-520	206	21	.	.	PROPN
admet-520	206	22	hale	hale	PROPN
admet-520	206	23	,	,	PUNCT
admet-520	206	24	c.t	c.t	PROPN
admet-520	206	25	.	.	PROPN
admet-520	206	26	mant	mant	PROPN
admet-520	206	27	,	,	PUNCT
admet-520	206	28	r.e	r.e	PROPN
admet-520	206	29	.	.	PROPN
admet-520	206	30	hancock	hancock	PROPN
admet-520	206	31	,	,	PUNCT
admet-520	206	32	m.l	m.l	PROPN
admet-520	206	33	.	.	PROPN
admet-520	206	34	vasil	vasil	PROPN
admet-520	206	35	,	,	PUNCT
admet-520	206	36	m.g	m.g	PROPN
admet-520	206	37	.	.	PROPN
admet-520	206	38	netea	netea	PROPN
admet-520	206	39	,	,	PUNCT
admet-520	206	40	r.s	r.s	PROPN
admet-520	206	41	.	.	PROPN
admet-520	206	42	hodges	hodges	PROPN
admet-520	206	43	.	.	PUNCT
admet-520	207	1	effects	effect	NOUN
admet-520	207	2	of	of	ADP
admet-520	207	3	hydrophobicity	hydrophobicity	NOUN
admet-520	207	4	on	on	ADP
admet-520	207	5	the	the	DET
admet-520	207	6	antifungal	antifungal	ADJ
admet-520	207	7	activity	activity	NOUN
admet-520	207	8	of	of	ADP
admet-520	207	9	alpha	alpha	NOUN
admet-520	207	10	-	-	ADJ
admet-520	207	11	helical	helical	ADJ
admet-520	207	12	antimicrobial	antimicrobial	ADJ
admet-520	207	13	peptides	peptide	NOUN
admet-520	207	14	.	.	PUNCT
admet-520	208	1	chem	chem	NOUN
admet-520	208	2	biol	biol	PROPN
admet-520	208	3	drug	drug	PROPN
admet-520	208	4	des	des	X
admet-520	208	5	72	72	NUM
admet-520	208	6	(	(	PUNCT
admet-520	208	7	2008	2008	NUM
admet-520	208	8	)	)	PUNCT
admet-520	208	9	483	483	NUM
admet-520	208	10	-	-	SYM
admet-520	208	11	495	495	NUM
admet-520	208	12	.	.	PUNCT
admet-520	209	1	[	[	X
admet-520	209	2	12	12	NUM
admet-520	209	3	]	]	X
admet-520	209	4	j.l	j.l	PROPN
admet-520	209	5	.	.	PROPN
admet-520	209	6	meek	meek	PROPN
admet-520	209	7	.	.	PUNCT
admet-520	210	1	prediction	prediction	NOUN
admet-520	210	2	of	of	ADP
admet-520	210	3	peptide	peptide	ADJ
admet-520	210	4	retention	retention	NOUN
admet-520	210	5	times	time	NOUN
admet-520	210	6	in	in	ADP
admet-520	210	7	high	high	ADJ
admet-520	210	8	-	-	PUNCT
admet-520	210	9	pressure	pressure	NOUN
admet-520	210	10	liquid	liquid	ADJ
admet-520	210	11	chromatography	chromatography	NOUN
admet-520	210	12	on	on	ADP
admet-520	210	13	the	the	DET
admet-520	210	14	basis	basis	NOUN
admet-520	210	15	of	of	ADP
admet-520	210	16	amino	amino	NOUN
admet-520	210	17	acid	acid	NOUN
admet-520	210	18	composition	composition	NOUN
admet-520	210	19	.	.	PUNCT
admet-520	211	1	proc	proc	PROPN
admet-520	211	2	natl	natl	PROPN
admet-520	211	3	acad	acad	PROPN
admet-520	211	4	sci	sci	PROPN
admet-520	211	5	u	u	PROPN
admet-520	211	6	s	s	PROPN
admet-520	211	7	a	a	DET
admet-520	211	8	77	77	NUM
admet-520	211	9	(	(	PUNCT
admet-520	211	10	1980	1980	NUM
admet-520	211	11	)	)	PUNCT
admet-520	211	12	1632	1632	NUM
admet-520	211	13	-	-	SYM
admet-520	211	14	1636	1636	NUM
admet-520	211	15	.	.	PUNCT
admet-520	212	1	[	[	X
admet-520	212	2	13	13	NUM
admet-520	212	3	]	]	X
admet-520	212	4	d.	d.	PROPN
admet-520	212	5	guo	guo	PROPN
admet-520	212	6	,	,	PUNCT
admet-520	212	7	c.t	c.t	PROPN
admet-520	212	8	.	.	PROPN
admet-520	212	9	mant	mant	PROPN
admet-520	212	10	,	,	PUNCT
admet-520	212	11	a.k	a.k	PROPN
admet-520	212	12	.	.	PROPN
admet-520	212	13	taneja	taneja	PROPN
admet-520	212	14	,	,	PUNCT
admet-520	212	15	j.m.r	j.m.r	PROPN
admet-520	212	16	.	.	PROPN
admet-520	212	17	parker	parker	PROPN
admet-520	212	18	,	,	PUNCT
admet-520	212	19	r.s	r.s	PROPN
admet-520	212	20	.	.	PROPN
admet-520	212	21	rodges	rodge	NOUN
admet-520	212	22	.	.	PUNCT
admet-520	213	1	prediction	prediction	NOUN
admet-520	213	2	of	of	ADP
admet-520	213	3	peptide	peptide	ADJ
admet-520	213	4	retention	retention	NOUN
admet-520	213	5	times	time	NOUN
admet-520	213	6	in	in	ADP
admet-520	213	7	reversed	reversed	ADJ
admet-520	213	8	-	-	PUNCT
admet-520	213	9	phase	phase	NOUN
admet-520	213	10	high	high	ADJ
admet-520	213	11	-	-	PUNCT
admet-520	213	12	performance	performance	NOUN
admet-520	213	13	liquid	liquid	ADJ
admet-520	213	14	chromatography	chromatography	NOUN
admet-520	213	15	i.	i.	NOUN
admet-520	213	16	determination	determination	NOUN
admet-520	213	17	of	of	ADP
admet-520	213	18	retention	retention	NOUN
admet-520	213	19	coefficients	coefficient	NOUN
admet-520	213	20	of	of	ADP
admet-520	213	21	amino	amino	NOUN
admet-520	213	22	acid	acid	NOUN
admet-520	213	23	residues	residue	NOUN
admet-520	213	24	of	of	ADP
admet-520	213	25	model	model	NOUN
admet-520	213	26	synthetic	synthetic	ADJ
admet-520	213	27	peptides	peptide	NOUN
admet-520	213	28	.	.	PUNCT
admet-520	214	1	j	j	PROPN
admet-520	214	2	chromatogr	chromatogr	VERB
admet-520	214	3	a	a	DET
admet-520	214	4	359	359	NUM
admet-520	214	5	(	(	PUNCT
admet-520	214	6	1986	1986	NUM
admet-520	214	7	)	)	PUNCT
admet-520	214	8	499	499	NUM
admet-520	214	9	-	-	SYM
admet-520	214	10	518	518	NUM
admet-520	214	11	.	.	PUNCT
admet-520	215	1	[	[	X
admet-520	215	2	14	14	NUM
admet-520	215	3	]	]	X
admet-520	215	4	e.f	e.f	PROPN
admet-520	215	5	.	.	PROPN
admet-520	215	6	strittmatter	strittmatter	PROPN
admet-520	215	7	,	,	PUNCT
admet-520	215	8	l.j	l.j	PROPN
admet-520	215	9	.	.	PROPN
admet-520	215	10	kangas	kangas	PROPN
admet-520	215	11	,	,	PUNCT
admet-520	215	12	k.	k.	PROPN
admet-520	215	13	petritis	petritis	PROPN
admet-520	215	14	,	,	PUNCT
admet-520	215	15	h.m	h.m	PROPN
admet-520	215	16	.	.	PROPN
admet-520	215	17	mottaz	mottaz	PROPN
admet-520	215	18	,	,	PUNCT
admet-520	215	19	g.a	g.a	PROPN
admet-520	215	20	.	.	PROPN
admet-520	215	21	anderson	anderson	PROPN
admet-520	215	22	,	,	PUNCT
admet-520	215	23	y.	y.	PROPN
admet-520	215	24	shen	shen	PROPN
admet-520	215	25	,	,	PUNCT
admet-520	215	26	j.m	j.m	PROPN
admet-520	215	27	.	.	PROPN
admet-520	215	28	jacobs	jacobs	PROPN
admet-520	215	29	,	,	PUNCT
admet-520	215	30	d.g	d.g	PROPN
admet-520	215	31	.	.	PROPN
admet-520	215	32	camp	camp	NOUN
admet-520	215	33	,	,	PUNCT
admet-520	215	34	r.d	r.d	PROPN
admet-520	215	35	.	.	PROPN
admet-520	215	36	smith	smith	PROPN
admet-520	215	37	.	.	PUNCT
admet-520	216	1	application	application	NOUN
admet-520	216	2	of	of	ADP
admet-520	216	3	peptide	peptide	NOUN
admet-520	216	4	lc	lc	PROPN
admet-520	216	5	retention	retention	NOUN
admet-520	216	6	time	time	NOUN
admet-520	216	7	information	information	NOUN
admet-520	216	8	in	in	ADP
admet-520	216	9	a	a	DET
admet-520	216	10	discriminant	discriminant	NOUN
admet-520	216	11	function	function	NOUN
admet-520	216	12	for	for	ADP
admet-520	216	13	peptide	peptide	ADJ
admet-520	216	14	identification	identification	NOUN
admet-520	216	15	by	by	ADP
admet-520	216	16	tandem	tandem	PROPN
admet-520	216	17	mass	mass	PROPN
admet-520	216	18	spectrometry	spectrometry	NOUN
admet-520	216	19	.	.	PUNCT
admet-520	217	1	j	j	PROPN
admet-520	217	2	proteome	proteome	PROPN
admet-520	217	3	res	re	VERB
admet-520	217	4	3	3	NUM
admet-520	217	5	(	(	PUNCT
admet-520	217	6	2004	2004	NUM
admet-520	217	7	)	)	PUNCT
admet-520	218	1	760	760	NUM
admet-520	218	2	-	-	SYM
admet-520	218	3	769	769	NUM
admet-520	218	4	.	.	PUNCT
admet-520	219	1	[	[	X
admet-520	219	2	15	15	NUM
admet-520	219	3	]	]	X
admet-520	219	4	r.	r.	PROPN
admet-520	219	5	kiyonami	kiyonami	PROPN
admet-520	219	6	,	,	PUNCT
admet-520	219	7	a.	a.	NOUN
admet-520	219	8	schoen	schoen	PROPN
admet-520	219	9	,	,	PUNCT
admet-520	219	10	a.	a.	PROPN
admet-520	219	11	prakash	prakash	PROPN
admet-520	219	12	,	,	PUNCT
admet-520	219	13	s.	s.	PROPN
admet-520	219	14	peterman	peterman	PROPN
admet-520	219	15	,	,	PUNCT
admet-520	219	16	v.	v.	PROPN
admet-520	219	17	zabrouskov	zabrouskov	PROPN
admet-520	219	18	,	,	PUNCT
admet-520	219	19	p.	p.	NOUN
admet-520	219	20	picotti	picotti	PROPN
admet-520	219	21	,	,	PUNCT
admet-520	219	22	r.	r.	PROPN
admet-520	219	23	aebersold	aebersold	PROPN
admet-520	219	24	,	,	PUNCT
admet-520	219	25	a.	a.	NOUN
admet-520	219	26	huhmer	huhmer	NOUN
admet-520	219	27	,	,	PUNCT
admet-520	219	28	b.	b.	PROPN
admet-520	219	29	domon	domon	PROPN
admet-520	219	30	.	.	PUNCT
admet-520	220	1	increased	increase	VERB
admet-520	220	2	selectivity	selectivity	NOUN
admet-520	220	3	,	,	PUNCT
admet-520	220	4	analytical	analytical	ADJ
admet-520	220	5	precision	precision	NOUN
admet-520	220	6	,	,	PUNCT
admet-520	220	7	and	and	CCONJ
admet-520	220	8	throughput	throughput	NOUN
admet-520	220	9	in	in	ADP
admet-520	220	10	targeted	target	VERB
admet-520	220	11	proteomics	proteomic	NOUN
admet-520	220	12	.	.	PUNCT
admet-520	221	1	mol	mol	ADP
admet-520	221	2	cell	cell	NOUN
admet-520	221	3	proteomics	proteomic	NOUN
admet-520	221	4	10	10	NUM
admet-520	221	5	(	(	PUNCT
admet-520	221	6	2011	2011	NUM
admet-520	221	7	)	)	PUNCT
admet-520	221	8	m110	m110	PROPN
admet-520	221	9	002931	002931	NUM
admet-520	221	10	.	.	PUNCT
admet-520	222	1	[	[	X
admet-520	222	2	16	16	NUM
admet-520	222	3	]	]	X
admet-520	222	4	v.	v.	PROPN
admet-520	222	5	spicer	spicer	PROPN
admet-520	222	6	,	,	PUNCT
admet-520	222	7	p.	p.	PROPN
admet-520	222	8	ezzati	ezzati	PROPN
admet-520	222	9	,	,	PUNCT
admet-520	222	10	h.	h.	PROPN
admet-520	222	11	neustaeter	neustaeter	PROPN
admet-520	222	12	,	,	PUNCT
admet-520	222	13	r.c	r.c	PROPN
admet-520	222	14	.	.	PROPN
admet-520	222	15	beavis	beavis	PROPN
admet-520	222	16	,	,	PUNCT
admet-520	222	17	j.a	j.a	PROPN
admet-520	222	18	.	.	PROPN
admet-520	222	19	wilkins	wilkins	PROPN
admet-520	222	20	,	,	PUNCT
admet-520	222	21	o.v	o.v	PROPN
admet-520	222	22	.	.	PROPN
admet-520	222	23	krokhin	krokhin	PROPN
admet-520	222	24	.	.	PUNCT
admet-520	223	1	3d	3d	PROPN
admet-520	223	2	hplc	hplc	PROPN
admet-520	223	3	-	-	PUNCT
admet-520	223	4	ms	ms	PROPN
admet-520	223	5	with	with	ADP
admet-520	223	6	reversed	reverse	VERB
admet-520	223	7	-	-	PUNCT
admet-520	223	8	phase	phase	NOUN
admet-520	223	9	separation	separation	NOUN
admet-520	223	10	functionality	functionality	NOUN
admet-520	223	11	in	in	ADP
admet-520	223	12	all	all	DET
admet-520	223	13	three	three	NUM
admet-520	223	14	dimensions	dimension	NOUN
admet-520	223	15	for	for	ADP
admet-520	223	16	large	large	ADJ
admet-520	223	17	-	-	PUNCT
admet-520	223	18	scale	scale	NOUN
admet-520	223	19	bottom	bottom	ADJ
admet-520	223	20	-	-	PUNCT
admet-520	223	21	up	up	ADP
admet-520	223	22	proteomics	proteomic	NOUN
admet-520	223	23	and	and	CCONJ
admet-520	223	24	peptide	peptide	NOUN
admet-520	223	25	retention	retention	NOUN
admet-520	223	26	data	datum	NOUN
admet-520	223	27	collection	collection	NOUN
admet-520	223	28	.	.	PUNCT
admet-520	224	1	anal	anal	ADJ
admet-520	224	2	chem	chem	NOUN
admet-520	224	3	88	88	NUM
admet-520	224	4	(	(	PUNCT
admet-520	224	5	2016	2016	NUM
admet-520	224	6	)	)	PUNCT
admet-520	224	7	2847	2847	NUM
admet-520	224	8	-	-	SYM
admet-520	224	9	2855	2855	NUM
admet-520	224	10	.	.	PUNCT
admet-520	225	1	[	[	X
admet-520	225	2	17	17	NUM
admet-520	225	3	]	]	X
admet-520	225	4	o.v	o.v	PROPN
admet-520	225	5	.	.	PROPN
admet-520	225	6	krokhin	krokhin	PROPN
admet-520	225	7	,	,	PUNCT
admet-520	225	8	r.	r.	PROPN
admet-520	225	9	craig	craig	PROPN
admet-520	225	10	,	,	PUNCT
admet-520	225	11	v.	v.	PROPN
admet-520	225	12	spicer	spicer	PROPN
admet-520	225	13	,	,	PUNCT
admet-520	225	14	w.	w.	PROPN
admet-520	225	15	ens	ens	PROPN
admet-520	225	16	,	,	PUNCT
admet-520	225	17	k.g	k.g	PROPN
admet-520	225	18	.	.	PROPN
admet-520	225	19	standing	standing	PROPN
admet-520	225	20	,	,	PUNCT
admet-520	225	21	r.c	r.c	PROPN
admet-520	225	22	.	.	PROPN
admet-520	225	23	beavis	beavis	PROPN
admet-520	225	24	,	,	PUNCT
admet-520	225	25	j.a	j.a	PROPN
admet-520	225	26	.	.	PROPN
admet-520	225	27	wilkins	wilkins	PROPN
admet-520	225	28	.	.	PUNCT
admet-520	226	1	an	an	DET
admet-520	226	2	improved	improved	ADJ
admet-520	226	3	model	model	NOUN
admet-520	226	4	for	for	ADP
admet-520	226	5	prediction	prediction	NOUN
admet-520	226	6	of	of	ADP
admet-520	226	7	retention	retention	NOUN
admet-520	226	8	times	time	NOUN
admet-520	226	9	of	of	ADP
admet-520	226	10	tryptic	tryptic	ADJ
admet-520	226	11	peptides	peptide	NOUN
admet-520	226	12	in	in	ADP
admet-520	226	13	ion	ion	NOUN
admet-520	226	14	pair	pair	NOUN
admet-520	226	15	reversed	reverse	VERB
admet-520	226	16	-	-	PUNCT
admet-520	226	17	phase	phase	NOUN
admet-520	226	18	hplc	hplc	NOUN
admet-520	226	19	:	:	PUNCT
admet-520	226	20	its	its	PRON
admet-520	226	21	application	application	NOUN
admet-520	226	22	to	to	ADP
admet-520	226	23	protein	protein	NOUN
admet-520	226	24	peptide	peptide	NOUN
admet-520	226	25	mapping	mapping	NOUN
admet-520	226	26	by	by	ADP
admet-520	226	27	off	off	ADP
admet-520	226	28	-	-	PUNCT
admet-520	226	29	line	line	NOUN
admet-520	226	30	hplc	hplc	NOUN
admet-520	226	31	-	-	PUNCT
admet-520	226	32	maldi	maldi	NOUN
admet-520	226	33	ms	ms	PROPN
admet-520	226	34	.	.	PROPN
admet-520	226	35	mol	mol	ADP
admet-520	226	36	cell	cell	NOUN
admet-520	226	37	proteomics	proteomic	NOUN
admet-520	226	38	3	3	NUM
admet-520	226	39	(	(	PUNCT
admet-520	226	40	2004	2004	NUM
admet-520	226	41	)	)	PUNCT
admet-520	226	42	908	908	NUM
admet-520	226	43	-	-	SYM
admet-520	226	44	919	919	NUM
admet-520	226	45	.	.	PUNCT
admet-520	227	1	[	[	X
admet-520	227	2	18	18	NUM
admet-520	227	3	]	]	PUNCT
admet-520	227	4	k.	k.	PROPN
admet-520	227	5	petritis	petritis	PROPN
admet-520	227	6	,	,	PUNCT
admet-520	227	7	l.j	l.j	PROPN
admet-520	227	8	.	.	PROPN
admet-520	227	9	kangas	kangas	PROPN
admet-520	227	10	,	,	PUNCT
admet-520	227	11	b.	b.	PROPN
admet-520	227	12	yan	yan	PROPN
admet-520	227	13	,	,	PUNCT
admet-520	227	14	m.e	m.e	PROPN
admet-520	227	15	.	.	PROPN
admet-520	227	16	monroe	monroe	PROPN
admet-520	227	17	,	,	PUNCT
admet-520	227	18	e.f	e.f	PROPN
admet-520	227	19	.	.	PROPN
admet-520	227	20	strittmatter	strittmatter	PROPN
admet-520	227	21	,	,	PUNCT
admet-520	227	22	w.j	w.j	PROPN
admet-520	227	23	.	.	PROPN
admet-520	227	24	qian	qian	PROPN
admet-520	227	25	,	,	PUNCT
admet-520	227	26	j.n	j.n	PROPN
admet-520	227	27	.	.	PROPN
admet-520	227	28	adkins	adkins	PROPN
admet-520	227	29	,	,	PUNCT
admet-520	227	30	r.j	r.j	PROPN
admet-520	227	31	.	.	PROPN
admet-520	227	32	moore	moore	PROPN
admet-520	227	33	,	,	PUNCT
admet-520	227	34	y.	y.	PROPN
admet-520	227	35	xu	xu	PROPN
admet-520	227	36	,	,	PUNCT
admet-520	227	37	m.s	m.s	PROPN
admet-520	227	38	.	.	PROPN
admet-520	227	39	lipton	lipton	PROPN
admet-520	227	40	,	,	PUNCT
admet-520	227	41	d.g	d.g	PROPN
admet-520	227	42	.	.	PROPN
admet-520	227	43	camp	camp	NOUN
admet-520	227	44	,	,	PUNCT
admet-520	227	45	2nd	2nd	PROPN
admet-520	227	46	,	,	PUNCT
admet-520	227	47	r.d	r.d	PROPN
admet-520	227	48	.	.	PROPN
admet-520	227	49	smith	smith	PROPN
admet-520	227	50	.	.	PROPN
admet-520	227	51	improved	improve	VERB
admet-520	227	52	peptide	peptide	ADJ
admet-520	227	53	elution	elution	NOUN
admet-520	227	54	time	time	NOUN
admet-520	227	55	prediction	prediction	NOUN
admet-520	227	56	for	for	ADP
admet-520	227	57	reversed	reversed	ADJ
admet-520	227	58	-	-	PUNCT
admet-520	227	59	phase	phase	NOUN
admet-520	227	60	liquid	liquid	ADJ
admet-520	227	61	chromatography	chromatography	NOUN
admet-520	227	62	-	-	PUNCT
admet-520	227	63	ms	ms	NOUN
admet-520	227	64	by	by	ADP
admet-520	227	65	incorporating	incorporate	VERB
admet-520	227	66	peptide	peptide	ADJ
admet-520	227	67	sequence	sequence	NOUN
admet-520	227	68	information	information	NOUN
admet-520	227	69	.	.	PUNCT
admet-520	228	1	anal	anal	ADJ
admet-520	228	2	chem	chem	NOUN
admet-520	228	3	78	78	NUM
admet-520	228	4	(	(	PUNCT
admet-520	228	5	2006	2006	NUM
admet-520	228	6	)	)	PUNCT
admet-520	228	7	5026	5026	NUM
admet-520	228	8	-	-	SYM
admet-520	228	9	5039	5039	NUM
admet-520	228	10	.	.	PUNCT
admet-520	229	1	[	[	X
admet-520	229	2	19	19	NUM
admet-520	229	3	]	]	X
admet-520	229	4	o.v	o.v	PROPN
admet-520	229	5	.	.	PROPN
admet-520	229	6	krokhin	krokhin	PROPN
admet-520	229	7	.	.	PUNCT
admet-520	230	1	sequence	sequence	NOUN
admet-520	230	2	-	-	PUNCT
admet-520	230	3	specific	specific	ADJ
admet-520	230	4	retention	retention	NOUN
admet-520	230	5	calculator	calculator	NOUN
admet-520	230	6	.	.	PUNCT
admet-520	231	1	algorithm	algorithm	PROPN
admet-520	231	2	for	for	ADP
admet-520	231	3	peptide	peptide	ADJ
admet-520	231	4	retention	retention	NOUN
admet-520	231	5	prediction	prediction	NOUN
admet-520	231	6	in	in	ADP
admet-520	231	7	ion	ion	NOUN
admet-520	231	8	-	-	PUNCT
admet-520	231	9	pair	pair	NOUN
admet-520	231	10	rp	rp	NOUN
admet-520	231	11	-	-	PUNCT
admet-520	231	12	hplc	hplc	NOUN
admet-520	231	13	:	:	PUNCT
admet-520	231	14	application	application	NOUN
admet-520	231	15	to	to	ADP
admet-520	231	16	300and	300and	NUM
admet-520	231	17	100	100	NUM
admet-520	231	18	-	-	PUNCT
admet-520	231	19	a	a	DET
admet-520	231	20	pore	pore	ADJ
admet-520	231	21	size	size	NOUN
admet-520	231	22	c18	c18	NOUN
admet-520	231	23	sorbents	sorbent	NOUN
admet-520	231	24	.	.	PUNCT
admet-520	232	1	anal	anal	ADJ
admet-520	232	2	chem	chem	NOUN
admet-520	232	3	78	78	NUM
admet-520	232	4	(	(	PUNCT
admet-520	232	5	2006	2006	NUM
admet-520	232	6	)	)	PUNCT
admet-520	232	7	77857795	77857795	NUM
admet-520	232	8	.	.	PUNCT
admet-520	233	1	[	[	X
admet-520	233	2	20	20	NUM
admet-520	233	3	]	]	X
admet-520	233	4	r.c	r.c	PROPN
admet-520	233	5	.	.	PROPN
admet-520	233	6	dwivedi	dwivedi	PROPN
admet-520	233	7	,	,	PUNCT
admet-520	233	8	v.	v.	PROPN
admet-520	233	9	spicer	spicer	PROPN
admet-520	233	10	,	,	PUNCT
admet-520	233	11	m.	m.	NOUN
admet-520	233	12	harder	hard	ADV
admet-520	233	13	,	,	PUNCT
admet-520	233	14	m.	m.	NOUN
admet-520	233	15	antonovici	antonovici	PROPN
admet-520	233	16	,	,	PUNCT
admet-520	233	17	w.	w.	PROPN
admet-520	233	18	ens	ens	PROPN
admet-520	233	19	,	,	PUNCT
admet-520	233	20	k.g	k.g	PROPN
admet-520	233	21	.	.	PROPN
admet-520	233	22	standing	standing	PROPN
admet-520	233	23	,	,	PUNCT
admet-520	233	24	j.a	j.a	PROPN
admet-520	233	25	.	.	PROPN
admet-520	233	26	wilkins	wilkins	PROPN
admet-520	233	27	,	,	PUNCT
admet-520	233	28	o.v	o.v	PROPN
admet-520	233	29	.	.	PROPN
admet-520	233	30	krokhin	krokhin	PROPN
admet-520	233	31	.	.	PUNCT
admet-520	234	1	practical	practical	ADJ
admet-520	234	2	implementation	implementation	NOUN
admet-520	234	3	of	of	ADP
admet-520	234	4	2d	2d	NUM
admet-520	234	5	hplc	hplc	NOUN
admet-520	234	6	scheme	scheme	NOUN
admet-520	234	7	with	with	ADP
admet-520	234	8	accurate	accurate	ADJ
admet-520	234	9	peptide	peptide	NOUN
admet-520	234	10	retention	retention	NOUN
admet-520	234	11	prediction	prediction	NOUN
admet-520	234	12	in	in	ADP
admet-520	234	13	both	both	DET
admet-520	234	14	dimensions	dimension	NOUN
admet-520	234	15	for	for	ADP
admet-520	234	16	high	high	ADJ
admet-520	234	17	-	-	PUNCT
admet-520	234	18	throughput	throughput	NOUN
admet-520	234	19	bottom	bottom	ADJ
admet-520	234	20	-	-	PUNCT
admet-520	234	21	up	up	ADP
admet-520	234	22	proteomics	proteomic	NOUN
admet-520	234	23	.	.	PUNCT
admet-520	235	1	anal	anal	ADJ
admet-520	235	2	chem	chem	NOUN
admet-520	235	3	80	80	NUM
admet-520	235	4	(	(	PUNCT
admet-520	235	5	2008	2008	NUM
admet-520	235	6	)	)	PUNCT
admet-520	235	7	7036	7036	NUM
admet-520	235	8	-	-	SYM
admet-520	235	9	7042	7042	NUM
admet-520	235	10	.	.	PUNCT
admet-520	236	1	[	[	X
admet-520	236	2	21	21	NUM
admet-520	236	3	]	]	X
admet-520	236	4	o.v	o.v	PROPN
admet-520	236	5	.	.	PROPN
admet-520	236	6	krokhin	krokhin	PROPN
admet-520	236	7	,	,	PUNCT
admet-520	236	8	p.	p.	PROPN
admet-520	236	9	ezzati	ezzati	PROPN
admet-520	236	10	,	,	PUNCT
admet-520	236	11	v.	v.	PROPN
admet-520	236	12	spicer	spicer	PROPN
admet-520	236	13	.	.	PUNCT
admet-520	237	1	peptide	peptide	ADJ
admet-520	237	2	retention	retention	NOUN
admet-520	237	3	time	time	NOUN
admet-520	237	4	prediction	prediction	NOUN
admet-520	237	5	in	in	ADP
admet-520	237	6	hydrophilic	hydrophilic	ADJ
admet-520	237	7	interaction	interaction	NOUN
admet-520	237	8	liquid	liquid	ADJ
admet-520	237	9	chromatography	chromatography	NOUN
admet-520	237	10	:	:	PUNCT
admet-520	237	11	data	datum	NOUN
admet-520	237	12	collection	collection	NOUN
admet-520	237	13	methods	method	NOUN
admet-520	237	14	and	and	CCONJ
admet-520	237	15	features	feature	NOUN
admet-520	237	16	of	of	ADP
admet-520	237	17	additive	additive	ADJ
admet-520	237	18	and	and	CCONJ
admet-520	237	19	sequence	sequence	NOUN
admet-520	237	20	-	-	PUNCT
admet-520	237	21	specific	specific	ADJ
admet-520	237	22	models	model	NOUN
admet-520	237	23	.	.	PUNCT
admet-520	238	1	anal	anal	ADJ
admet-520	238	2	chem	chem	NOUN
admet-520	238	3	89	89	NUM
admet-520	238	4	(	(	PUNCT
admet-520	238	5	2017	2017	NUM
admet-520	238	6	)	)	PUNCT
admet-520	238	7	5526	5526	NUM
admet-520	238	8	-	-	SYM
admet-520	238	9	5533	5533	NUM
admet-520	238	10	.	.	PUNCT
admet-520	239	1	[	[	X
admet-520	239	2	22	22	NUM
admet-520	239	3	]	]	X
admet-520	239	4	d.	d.	PROPN
admet-520	239	5	gussakovsky	gussakovsky	PROPN
admet-520	239	6	,	,	PUNCT
admet-520	239	7	h.	h.	PROPN
admet-520	239	8	neustaeter	neustaeter	PROPN
admet-520	239	9	,	,	PUNCT
admet-520	239	10	v.	v.	PROPN
admet-520	239	11	spicer	spicer	PROPN
admet-520	239	12	,	,	PUNCT
admet-520	239	13	o.v	o.v	PROPN
admet-520	239	14	.	.	PROPN
admet-520	239	15	krokhin	krokhin	PROPN
admet-520	239	16	.	.	PUNCT
admet-520	240	1	sequence	sequence	NOUN
admet-520	240	2	-	-	PUNCT
admet-520	240	3	specific	specific	ADJ
admet-520	240	4	model	model	NOUN
admet-520	240	5	for	for	ADP
admet-520	240	6	peptide	peptide	ADJ
admet-520	240	7	retention	retention	NOUN
admet-520	240	8	time	time	NOUN
admet-520	240	9	prediction	prediction	NOUN
admet-520	240	10	in	in	ADP
admet-520	240	11	strong	strong	ADJ
admet-520	240	12	cation	cation	NOUN
admet-520	240	13	exchange	exchange	NOUN
admet-520	240	14	chromatography	chromatography	NOUN
admet-520	240	15	.	.	PUNCT
admet-520	241	1	anal	anal	ADJ
admet-520	241	2	chem	chem	NOUN
admet-520	241	3	89	89	NUM
admet-520	241	4	(	(	PUNCT
admet-520	241	5	2017	2017	NUM
admet-520	241	6	)	)	PUNCT
admet-520	241	7	11795	11795	NUM
admet-520	241	8	-	-	SYM
admet-520	241	9	11802	11802	NUM
admet-520	241	10	.	.	PUNCT
admet-520	242	1	[	[	X
admet-520	242	2	23	23	NUM
admet-520	242	3	]	]	X
admet-520	242	4	o.v	o.v	PROPN
admet-520	242	5	.	.	PROPN
admet-520	242	6	krokhin	krokhin	PROPN
admet-520	242	7	,	,	PUNCT
admet-520	242	8	g.	g.	PROPN
admet-520	242	9	anderson	anderson	PROPN
admet-520	242	10	,	,	PUNCT
admet-520	242	11	v.	v.	PROPN
admet-520	242	12	spicer	spicer	PROPN
admet-520	242	13	,	,	PUNCT
admet-520	242	14	l.	l.	PROPN
admet-520	242	15	sun	sun	PROPN
admet-520	242	16	,	,	PUNCT
admet-520	242	17	n.j	n.j	PROPN
admet-520	242	18	.	.	PROPN
admet-520	242	19	dovichi	dovichi	PROPN
admet-520	242	20	.	.	PUNCT
admet-520	243	1	predicting	predict	VERB
admet-520	243	2	electrophoretic	electrophoretic	ADJ
admet-520	243	3	mobility	mobility	NOUN
admet-520	243	4	of	of	ADP
admet-520	243	5	tryptic	tryptic	ADJ
admet-520	243	6	peptides	peptide	NOUN
admet-520	243	7	for	for	ADP
admet-520	243	8	high	high	ADJ
admet-520	243	9	-	-	PUNCT
admet-520	243	10	throughput	throughput	NOUN
admet-520	243	11	cze	cze	NOUN
admet-520	243	12	-	-	PUNCT
admet-520	243	13	ms	ms	NOUN
admet-520	243	14	analysis	analysis	NOUN
admet-520	243	15	.	.	PUNCT
admet-520	244	1	anal	anal	ADJ
admet-520	244	2	chem	chem	NOUN
admet-520	244	3	89	89	NUM
admet-520	244	4	(	(	PUNCT
admet-520	244	5	2017	2017	NUM
admet-520	244	6	)	)	PUNCT
admet-520	244	7	2000	2000	NUM
admet-520	244	8	-	-	SYM
admet-520	244	9	2008	2008	NUM
admet-520	244	10	.	.	PUNCT
admet-520	245	1	[	[	X
admet-520	245	2	24	24	NUM
admet-520	245	3	]	]	X
admet-520	245	4	o.v	o.v	PROPN
admet-520	245	5	.	.	PROPN
admet-520	245	6	krokhin	krokhin	PROPN
admet-520	245	7	,	,	PUNCT
admet-520	245	8	v.	v.	PROPN
admet-520	245	9	spicer	spicer	PROPN
admet-520	245	10	.	.	PUNCT
admet-520	246	1	peptide	peptide	ADJ
admet-520	246	2	retention	retention	NOUN
admet-520	246	3	standards	standard	NOUN
admet-520	246	4	and	and	CCONJ
admet-520	246	5	hydrophobicity	hydrophobicity	NOUN
admet-520	246	6	indexes	index	NOUN
admet-520	246	7	in	in	ADP
admet-520	246	8	reversed	reverse	VERB
admet-520	246	9	-	-	PUNCT
admet-520	246	10	phase	phase	NOUN
admet-520	246	11	high	high	ADJ
admet-520	246	12	-	-	PUNCT
admet-520	246	13	performance	performance	NOUN
admet-520	246	14	liquid	liquid	ADJ
admet-520	246	15	chromatography	chromatography	NOUN
admet-520	246	16	of	of	ADP
admet-520	246	17	peptides	peptide	NOUN
admet-520	246	18	.	.	PUNCT
admet-520	247	1	anal	anal	ADJ
admet-520	247	2	chem	chem	NOUN
admet-520	247	3	81	81	NUM
admet-520	247	4	(	(	PUNCT
admet-520	247	5	2009	2009	NUM
admet-520	247	6	)	)	PUNCT
admet-520	247	7	9522	9522	NUM
admet-520	247	8	-	-	SYM
admet-520	247	9	9530	9530	NUM
admet-520	247	10	.	.	PUNCT
admet-520	248	1	©	©	PROPN
admet-520	248	2	2018	2018	NUM
admet-520	248	3	by	by	ADP
admet-520	248	4	the	the	DET
admet-520	248	5	authors	author	NOUN
admet-520	248	6	;	;	PUNCT
admet-520	249	1	licensee	licensee	PROPN
admet-520	249	2	iapc	iapc	PROPN
admet-520	249	3	,	,	PUNCT
admet-520	249	4	zagreb	zagreb	PROPN
admet-520	249	5	,	,	PUNCT
admet-520	249	6	croatia	croatia	PROPN
admet-520	249	7	.	.	PUNCT
admet-520	250	1	this	this	DET
admet-520	250	2	article	article	NOUN
admet-520	250	3	is	be	AUX
admet-520	250	4	an	an	DET
admet-520	250	5	open	open	ADJ
admet-520	250	6	-	-	PUNCT
admet-520	250	7	access	access	NOUN
admet-520	250	8	article	article	NOUN
admet-520	250	9	distributed	distribute	VERB
admet-520	250	10	under	under	ADP
admet-520	250	11	the	the	DET
admet-520	250	12	terms	term	NOUN
admet-520	250	13	and	and	CCONJ
admet-520	250	14	conditions	condition	NOUN
admet-520	250	15	of	of	ADP
admet-520	250	16	the	the	DET
admet-520	250	17	creative	creative	ADJ
admet-520	250	18	commons	common	NOUN
admet-520	250	19	attribution	attribution	NOUN
admet-520	250	20	license	license	NOUN
admet-520	250	21	(	(	PUNCT
admet-520	250	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-520	250	23	)	)	PUNCT
admet-520	250	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN