id	sid	tid	token	lemma	pos
admet-641	1	1	computational	computational	ADJ
admet-641	1	2	screens	screen	NOUN
admet-641	1	3	can	can	AUX
admet-641	1	4	speed	speed	VERB
admet-641	1	5	up	up	ADP
admet-641	1	6	the	the	DET
admet-641	1	7	discovery	discovery	NOUN
admet-641	1	8	of	of	ADP
admet-641	1	9	pharmaceutical	pharmaceutical	ADJ
admet-641	1	10	cocrystals	cocrystal	NOUN
admet-641	1	11	doi	doi	NOUN
admet-641	1	12	:	:	PUNCT
admet-641	1	13	10.5599	10.5599	NUM
admet-641	1	14	/	/	SYM
admet-641	1	15	admet.641	admet.641	PROPN
admet-641	1	16	284	284	NUM
admet-641	1	17	admet	admet	X
admet-641	1	18	&	&	CCONJ
admet-641	1	19	dmpk	dmpk	PROPN
admet-641	1	20	6(4	6(4	PROPN
admet-641	1	21	)	)	PUNCT
admet-641	1	22	(	(	PUNCT
admet-641	1	23	2018	2018	NUM
admet-641	1	24	)	)	PUNCT
admet-641	1	25	284	284	NUM
admet-641	1	26	-	-	SYM
admet-641	1	27	287	287	NUM
admet-641	1	28	;	;	PUNCT
admet-641	1	29	doi	doi	NOUN
admet-641	1	30	:	:	PUNCT
admet-641	1	31	http://dx.doi.org/10.5599/admet.641	http://dx.doi.org/10.5599/admet.641	VERB
admet-641	1	32	open	open	ADJ
admet-641	1	33	access	access	NOUN
admet-641	1	34	:	:	PUNCT
admet-641	2	1	issn	issn	NOUN
admet-641	2	2	:	:	PUNCT
admet-641	2	3	1848	1848	NUM
admet-641	2	4	-	-	SYM
admet-641	2	5	7718	7718	NUM
admet-641	2	6	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-641	2	7	communication	communication	NOUN
admet-641	2	8	computational	computational	ADJ
admet-641	2	9	screens	screen	NOUN
admet-641	2	10	can	can	AUX
admet-641	2	11	speed	speed	VERB
admet-641	2	12	up	up	ADP
admet-641	2	13	the	the	DET
admet-641	2	14	discovery	discovery	NOUN
admet-641	2	15	of	of	ADP
admet-641	2	16	pharmaceutical	pharmaceutical	ADJ
admet-641	2	17	cocrystals	cocrystal	NOUN
admet-641	2	18	rafel	rafel	VERB
admet-641	2	19	prohensa	prohensa	NOUN
admet-641	2	20	and	and	CCONJ
admet-641	2	21	christopher	christopher	PROPN
admet-641	2	22	a.	a.	PROPN
admet-641	2	23	hunterb	hunterb	PROPN
admet-641	2	24	a	a	DET
admet-641	2	25	unitat	unitat	NOUN
admet-641	2	26	de	de	NOUN
admet-641	2	27	polimorfisme	polimorfisme	NOUN
admet-641	2	28	i	i	PRON
admet-641	2	29	calorimetria	calorimetria	PROPN
admet-641	2	30	,	,	PUNCT
admet-641	2	31	centres	centre	VERB
admet-641	2	32	científics	científic	NOUN
admet-641	2	33	i	i	PROPN
admet-641	2	34	tecnològics	tecnològic	NOUN
admet-641	2	35	,	,	PUNCT
admet-641	2	36	universitat	universitat	PROPN
admet-641	2	37	de	de	PROPN
admet-641	2	38	barcelona	barcelona	PROPN
admet-641	2	39	,	,	PUNCT
admet-641	2	40	baldiri	baldiri	PROPN
admet-641	2	41	reixac	reixac	ADJ
admet-641	2	42	10	10	NUM
admet-641	2	43	,	,	PUNCT
admet-641	2	44	08028	08028	NUM
admet-641	2	45	barcelona	barcelona	PROPN
admet-641	2	46	,	,	PUNCT
admet-641	2	47	spain	spain	PROPN
admet-641	2	48	b	b	PROPN
admet-641	2	49	department	department	PROPN
admet-641	2	50	of	of	ADP
admet-641	2	51	chemistry	chemistry	NOUN
admet-641	2	52	,	,	PUNCT
admet-641	2	53	university	university	PROPN
admet-641	2	54	of	of	ADP
admet-641	2	55	cambridge	cambridge	PROPN
admet-641	2	56	,	,	PUNCT
admet-641	2	57	lensfield	lensfield	NOUN
admet-641	2	58	road	road	NOUN
admet-641	2	59	,	,	PUNCT
admet-641	2	60	cambridge	cambridge	PROPN
admet-641	2	61	cb2	cb2	PROPN
admet-641	2	62	1ew	1ew	PROPN
admet-641	2	63	,	,	PUNCT
admet-641	2	64	uk	uk	PROPN
admet-641	2	65	e	e	NOUN
admet-641	2	66	-	-	PUNCT
admet-641	2	67	mails	mail	NOUN
admet-641	2	68	:	:	PUNCT
admet-641	2	69	rafel@ccit.ub.edu	rafel@ccit.ub.edu	PRON
admet-641	2	70	(	(	PUNCT
admet-641	2	71	prohens	prohen	NOUN
admet-641	2	72	)	)	PUNCT
admet-641	2	73	;	;	PUNCT
admet-641	2	74	herchelsmith.orgchem@ch.cam.ac.uk	herchelsmith.orgchem@ch.cam.ac.uk	X
admet-641	2	75	(	(	PUNCT
admet-641	2	76	hunter	hunter	NOUN
admet-641	2	77	)	)	PUNCT
admet-641	2	78	received	receive	VERB
admet-641	2	79	:	:	PUNCT
admet-641	2	80	november	november	PROPN
admet-641	2	81	26	26	NUM
admet-641	2	82	,	,	PUNCT
admet-641	2	83	2018	2018	NUM
admet-641	2	84	;	;	PUNCT
admet-641	2	85	accepted	accept	VERB
admet-641	2	86	:	:	PUNCT
admet-641	2	87	november	november	PROPN
admet-641	2	88	27	27	NUM
admet-641	2	89	,	,	PUNCT
admet-641	2	90	2018	2018	NUM
admet-641	2	91	;	;	PUNCT
admet-641	2	92	published	publish	VERB
admet-641	2	93	:	:	PUNCT
admet-641	2	94	december	december	PROPN
admet-641	2	95	27	27	NUM
admet-641	2	96	,	,	PUNCT
admet-641	2	97	2018	2018	NUM
admet-641	2	98	abstract	abstract	NOUN
admet-641	2	99	the	the	DET
admet-641	2	100	calculation	calculation	NOUN
admet-641	2	101	of	of	ADP
admet-641	2	102	surface	surface	NOUN
admet-641	2	103	site	site	NOUN
admet-641	2	104	interaction	interaction	NOUN
admet-641	2	105	points	point	NOUN
admet-641	2	106	for	for	ADP
admet-641	2	107	cocrystal	cocrystal	ADJ
admet-641	2	108	computational	computational	ADJ
admet-641	2	109	screens	screen	NOUN
admet-641	2	110	in	in	ADP
admet-641	2	111	combination	combination	NOUN
admet-641	2	112	with	with	ADP
admet-641	2	113	efficient	efficient	ADJ
admet-641	2	114	experimental	experimental	ADJ
admet-641	2	115	cocrystallization	cocrystallization	NOUN
admet-641	2	116	techniques	technique	NOUN
admet-641	2	117	has	have	AUX
admet-641	2	118	been	be	AUX
admet-641	2	119	applied	apply	VERB
admet-641	2	120	successfully	successfully	ADV
admet-641	2	121	to	to	ADP
admet-641	2	122	several	several	ADJ
admet-641	2	123	drug	drug	NOUN
admet-641	2	124	compounds	compound	NOUN
admet-641	2	125	.	.	PUNCT
admet-641	3	1	the	the	DET
admet-641	3	2	basics	basic	NOUN
admet-641	3	3	of	of	ADP
admet-641	3	4	this	this	DET
admet-641	3	5	combined	combine	VERB
admet-641	3	6	approach	approach	NOUN
admet-641	3	7	are	be	AUX
admet-641	3	8	briefly	briefly	ADV
admet-641	3	9	reviewed	review	VERB
admet-641	3	10	in	in	ADP
admet-641	3	11	this	this	DET
admet-641	3	12	communication	communication	NOUN
admet-641	3	13	.	.	PUNCT
admet-641	4	1	keywords	keyword	NOUN
admet-641	4	2	cocrystals	cocrystal	NOUN
admet-641	4	3	;	;	PUNCT
admet-641	4	4	virtual	virtual	ADJ
admet-641	4	5	screen	screen	NOUN
admet-641	4	6	;	;	PUNCT
admet-641	4	7	h	h	NOUN
admet-641	4	8	-	-	PUNCT
admet-641	4	9	bond	bond	NOUN
admet-641	4	10	parameters	parameter	NOUN
admet-641	4	11	the	the	DET
admet-641	4	12	search	search	NOUN
admet-641	4	13	for	for	ADP
admet-641	4	14	new	new	ADJ
admet-641	4	15	cocrystals	cocrystal	NOUN
admet-641	4	16	of	of	ADP
admet-641	4	17	apis	apis	PROPN
admet-641	4	18	can	can	AUX
admet-641	4	19	be	be	AUX
admet-641	4	20	very	very	ADV
admet-641	4	21	expensive	expensive	ADJ
admet-641	4	22	in	in	ADP
admet-641	4	23	terms	term	NOUN
admet-641	4	24	of	of	ADP
admet-641	4	25	time	time	NOUN
admet-641	4	26	and	and	CCONJ
admet-641	4	27	economical	economical	ADJ
admet-641	4	28	resources	resource	NOUN
admet-641	4	29	since	since	SCONJ
admet-641	4	30	the	the	DET
admet-641	4	31	number	number	NOUN
admet-641	4	32	of	of	ADP
admet-641	4	33	potential	potential	ADJ
admet-641	4	34	coformers	coformer	NOUN
admet-641	4	35	available	available	ADJ
admet-641	4	36	with	with	ADP
admet-641	4	37	suitable	suitable	ADJ
admet-641	4	38	toxicity	toxicity	NOUN
admet-641	4	39	profiles	profile	NOUN
admet-641	4	40	is	be	AUX
admet-641	4	41	huge	huge	ADJ
admet-641	4	42	.	.	PUNCT
admet-641	5	1	thus	thus	ADV
admet-641	5	2	,	,	PUNCT
admet-641	5	3	there	there	PRON
admet-641	5	4	is	be	VERB
admet-641	5	5	a	a	DET
admet-641	5	6	real	real	ADJ
admet-641	5	7	need	need	NOUN
admet-641	5	8	in	in	ADP
admet-641	5	9	the	the	DET
admet-641	5	10	pharmaceutical	pharmaceutical	ADJ
admet-641	5	11	industry	industry	NOUN
admet-641	5	12	to	to	PART
admet-641	5	13	optimize	optimize	VERB
admet-641	5	14	screening	screening	NOUN
admet-641	5	15	methodologies	methodology	NOUN
admet-641	5	16	,	,	PUNCT
admet-641	5	17	because	because	SCONJ
admet-641	5	18	cocrystals	cocrystal	NOUN
admet-641	5	19	offer	offer	VERB
admet-641	5	20	solutions	solution	NOUN
admet-641	5	21	to	to	ADP
admet-641	5	22	some	some	PRON
admet-641	5	23	of	of	ADP
admet-641	5	24	the	the	DET
admet-641	5	25	drawbacks	drawback	NOUN
admet-641	5	26	inherent	inherent	ADJ
admet-641	5	27	to	to	ADP
admet-641	5	28	many	many	ADJ
admet-641	5	29	drug	drug	NOUN
admet-641	5	30	candidates	candidate	NOUN
admet-641	5	31	,	,	PUNCT
admet-641	5	32	such	such	ADJ
admet-641	5	33	as	as	ADP
admet-641	5	34	low	low	ADJ
admet-641	5	35	solubility	solubility	NOUN
admet-641	5	36	and	and	CCONJ
admet-641	5	37	bioavailability	bioavailability	NOUN
admet-641	5	38	.	.	PUNCT
admet-641	6	1	historically	historically	ADV
admet-641	6	2	,	,	PUNCT
admet-641	6	3	the	the	DET
admet-641	6	4	supramolecular	supramolecular	ADJ
admet-641	6	5	synthon	synthon	ADJ
admet-641	6	6	approach	approach	NOUN
admet-641	6	7	has	have	AUX
admet-641	6	8	been	be	AUX
admet-641	6	9	the	the	DET
admet-641	6	10	paradigm	paradigm	NOUN
admet-641	6	11	of	of	ADP
admet-641	6	12	crystal	crystal	NOUN
admet-641	6	13	engineering	engineering	NOUN
admet-641	6	14	for	for	ADP
admet-641	6	15	the	the	DET
admet-641	6	16	design	design	NOUN
admet-641	6	17	of	of	ADP
admet-641	6	18	new	new	ADJ
admet-641	6	19	multicomponent	multicomponent	NOUN
admet-641	6	20	crystals	crystal	NOUN
admet-641	6	21	based	base	VERB
admet-641	6	22	on	on	ADP
admet-641	6	23	strong	strong	ADJ
admet-641	6	24	intermolecular	intermolecular	ADJ
admet-641	6	25	interactions	interaction	NOUN
admet-641	6	26	[	[	X
admet-641	6	27	1	1	NUM
admet-641	6	28	]	]	PUNCT
admet-641	6	29	.	.	PUNCT
admet-641	7	1	although	although	SCONJ
admet-641	7	2	very	very	ADV
admet-641	7	3	limited	limited	ADJ
admet-641	7	4	in	in	ADP
admet-641	7	5	the	the	DET
admet-641	7	6	scope	scope	NOUN
admet-641	7	7	for	for	ADP
admet-641	7	8	efficiently	efficiently	ADV
admet-641	7	9	locating	locate	VERB
admet-641	7	10	new	new	ADJ
admet-641	7	11	coformers	coformer	NOUN
admet-641	7	12	,	,	PUNCT
admet-641	7	13	supramolecular	supramolecular	ADJ
admet-641	7	14	synthons	synthon	NOUN
admet-641	7	15	are	be	AUX
admet-641	7	16	the	the	DET
admet-641	7	17	basis	basis	NOUN
admet-641	7	18	for	for	ADP
admet-641	7	19	understanding	understand	VERB
admet-641	7	20	the	the	DET
admet-641	7	21	formation	formation	NOUN
admet-641	7	22	of	of	ADP
admet-641	7	23	a	a	DET
admet-641	7	24	cocrystal	cocrystal	NOUN
admet-641	7	25	.	.	PUNCT
admet-641	8	1	more	more	ADV
admet-641	8	2	recently	recently	ADV
admet-641	8	3	other	other	ADJ
admet-641	8	4	approaches	approach	NOUN
admet-641	8	5	have	have	AUX
admet-641	8	6	been	be	AUX
admet-641	8	7	developed	develop	VERB
admet-641	8	8	for	for	ADP
admet-641	8	9	predicting	predict	VERB
admet-641	8	10	the	the	DET
admet-641	8	11	outcome	outcome	NOUN
admet-641	8	12	of	of	ADP
admet-641	8	13	cocrystallization	cocrystallization	NOUN
admet-641	8	14	experiments	experiment	NOUN
admet-641	8	15	.	.	PUNCT
admet-641	9	1	the	the	DET
admet-641	9	2	hansen	hansen	PROPN
admet-641	9	3	solubility	solubility	PROPN
admet-641	9	4	parameter	parameter	NOUN
admet-641	9	5	[	[	X
admet-641	9	6	2	2	NUM
admet-641	9	7	]	]	PUNCT
admet-641	9	8	has	have	AUX
admet-641	9	9	been	be	AUX
admet-641	9	10	investigated	investigate	VERB
admet-641	9	11	to	to	PART
admet-641	9	12	guide	guide	VERB
admet-641	9	13	cocrystal	cocrystal	ADJ
admet-641	9	14	screening	screening	NOUN
admet-641	9	15	.	.	PUNCT
admet-641	10	1	statistical	statistical	ADJ
admet-641	10	2	analyses	analysis	NOUN
admet-641	10	3	of	of	ADP
admet-641	10	4	the	the	DET
admet-641	10	5	properties	property	NOUN
admet-641	10	6	of	of	ADP
admet-641	10	7	compounds	compound	NOUN
admet-641	10	8	known	know	VERB
admet-641	10	9	to	to	PART
admet-641	10	10	form	form	VERB
admet-641	10	11	cocrystals	cocrystal	NOUN
admet-641	10	12	show	show	VERB
admet-641	10	13	promise	promise	NOUN
admet-641	10	14	.	.	PUNCT
admet-641	11	1	for	for	ADP
admet-641	11	2	example	example	NOUN
admet-641	11	3	,	,	PUNCT
admet-641	11	4	fabián	fabián	PROPN
admet-641	11	5	showed	show	VERB
admet-641	11	6	that	that	SCONJ
admet-641	11	7	cocrystals	cocrystal	NOUN
admet-641	11	8	are	be	AUX
admet-641	11	9	usually	usually	ADV
admet-641	11	10	formed	form	VERB
admet-641	11	11	by	by	ADP
admet-641	11	12	molecules	molecule	NOUN
admet-641	11	13	of	of	ADP
admet-641	11	14	similar	similar	ADJ
admet-641	11	15	shapes	shape	NOUN
admet-641	11	16	and	and	CCONJ
admet-641	11	17	polarities	polarity	NOUN
admet-641	11	18	[	[	X
admet-641	11	19	3	3	NUM
admet-641	11	20	]	]	PUNCT
admet-641	11	21	,	,	PUNCT
admet-641	11	22	and	and	CCONJ
admet-641	11	23	the	the	DET
admet-641	11	24	hydrogen	hydrogen	NOUN
admet-641	11	25	bond	bond	NOUN
admet-641	11	26	propensity	propensity	NOUN
admet-641	11	27	tool	tool	NOUN
admet-641	11	28	developed	develop	VERB
admet-641	11	29	by	by	ADP
admet-641	11	30	the	the	DET
admet-641	11	31	cambridge	cambridge	PROPN
admet-641	11	32	crystallographic	crystallographic	PROPN
admet-641	11	33	data	data	PROPN
admet-641	11	34	centre	centre	NOUN
admet-641	11	35	has	have	AUX
admet-641	11	36	been	be	AUX
admet-641	11	37	used	use	VERB
admet-641	11	38	to	to	PART
admet-641	11	39	predict	predict	VERB
admet-641	11	40	the	the	DET
admet-641	11	41	cocrystallization	cocrystallization	NOUN
admet-641	11	42	of	of	ADP
admet-641	11	43	several	several	ADJ
admet-641	11	44	apis	apis	NOUN
admet-641	12	1	[	[	X
admet-641	12	2	4	4	NUM
admet-641	12	3	]	]	PUNCT
admet-641	12	4	.	.	PUNCT
admet-641	13	1	computational	computational	ADJ
admet-641	13	2	methods	method	NOUN
admet-641	13	3	have	have	AUX
admet-641	13	4	also	also	ADV
admet-641	13	5	been	be	AUX
admet-641	13	6	applied	apply	VERB
admet-641	13	7	to	to	ADP
admet-641	13	8	the	the	DET
admet-641	13	9	cocrystal	cocrystal	ADJ
admet-641	13	10	problem	problem	NOUN
admet-641	13	11	.	.	PUNCT
admet-641	14	1	a	a	DET
admet-641	14	2	high	high	ADJ
admet-641	14	3	-	-	PUNCT
admet-641	14	4	level	level	NOUN
admet-641	14	5	dft	dft	NOUN
admet-641	14	6	study	study	NOUN
admet-641	14	7	of	of	ADP
admet-641	14	8	350	350	NUM
admet-641	14	9	organic	organic	ADJ
admet-641	14	10	cocrystals	cocrystal	NOUN
admet-641	14	11	concluded	conclude	VERB
admet-641	14	12	that	that	SCONJ
admet-641	14	13	the	the	DET
admet-641	14	14	formulation	formulation	NOUN
admet-641	14	15	of	of	ADP
admet-641	14	16	general	general	ADJ
admet-641	14	17	rules	rule	NOUN
admet-641	14	18	to	to	PART
admet-641	14	19	guide	guide	VERB
admet-641	14	20	cocrystal	cocrystal	ADJ
admet-641	14	21	formation	formation	NOUN
admet-641	14	22	remains	remain	VERB
admet-641	14	23	difficult	difficult	ADJ
admet-641	14	24	[	[	X
admet-641	14	25	5	5	NUM
admet-641	14	26	]	]	PUNCT
admet-641	14	27	.	.	PUNCT
admet-641	15	1	we	we	PRON
admet-641	15	2	have	have	AUX
admet-641	15	3	developed	develop	VERB
admet-641	15	4	a	a	DET
admet-641	15	5	fast	fast	ADJ
admet-641	15	6	computational	computational	ADJ
admet-641	15	7	method	method	NOUN
admet-641	15	8	to	to	PART
admet-641	15	9	screen	screen	VERB
admet-641	15	10	large	large	ADJ
admet-641	15	11	libraries	library	NOUN
admet-641	15	12	of	of	ADP
admet-641	15	13	coformers	coformer	NOUN
admet-641	15	14	[	[	X
admet-641	15	15	6	6	NUM
admet-641	15	16	]	]	PUNCT
admet-641	15	17	.	.	PUNCT
admet-641	16	1	the	the	DET
admet-641	16	2	approach	approach	NOUN
admet-641	16	3	uses	use	VERB
admet-641	16	4	hunter	hunter	NOUN
admet-641	16	5	's	's	PART
admet-641	16	6	hydrogen	hydrogen	NOUN
admet-641	16	7	bond	bond	NOUN
admet-641	16	8	parameters	parameter	NOUN
admet-641	16	9	(	(	PUNCT
admet-641	16	10			NOUN
admet-641	16	11	and	and	CCONJ
admet-641	16	12			NOUN
admet-641	16	13	)	)	PUNCT
admet-641	17	1	[	[	X
admet-641	17	2	7	7	X
admet-641	17	3	]	]	PUNCT
admet-641	17	4	to	to	PART
admet-641	17	5	predict	predict	VERB
admet-641	17	6	the	the	DET
admet-641	17	7	formation	formation	NOUN
admet-641	17	8	of	of	ADP
admet-641	17	9	intermolecular	intermolecular	ADJ
admet-641	17	10	interactions	interaction	NOUN
admet-641	17	11	in	in	ADP
admet-641	17	12	crystals	crystal	NOUN
admet-641	17	13	and	and	CCONJ
admet-641	17	14	is	be	AUX
admet-641	17	15	based	base	VERB
admet-641	17	16	on	on	ADP
admet-641	17	17	the	the	DET
admet-641	17	18	principle	principle	NOUN
admet-641	17	19	that	that	SCONJ
admet-641	17	20	the	the	DET
admet-641	17	21	crystal	crystal	NOUN
admet-641	17	22	structure	structure	NOUN
admet-641	17	23	of	of	ADP
admet-641	17	24	an	an	DET
admet-641	17	25	organic	organic	ADJ
admet-641	17	26	compound	compound	NOUN
admet-641	17	27	is	be	AUX
admet-641	17	28	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-641	17	29	mailto:rafel@ccit.ub.edu	mailto:rafel@ccit.ub.edu	PROPN
admet-641	17	30	mailto:herchelsmith.orgchem@ch.cam.ac.uk	mailto:herchelsmith.orgchem@ch.cam.ac.uk	NOUN
admet-641	17	31	admet	admet	PROPN
admet-641	17	32	&	&	CCONJ
admet-641	17	33	dmpk	dmpk	PROPN
admet-641	17	34	6(4	6(4	PROPN
admet-641	17	35	)	)	PUNCT
admet-641	17	36	(	(	PUNCT
admet-641	17	37	2018	2018	NUM
admet-641	17	38	)	)	PUNCT
admet-641	17	39	284	284	NUM
admet-641	17	40	-	-	SYM
admet-641	17	41	287	287	NUM
admet-641	17	42	computational	computational	ADJ
admet-641	17	43	screens	screen	NOUN
admet-641	17	44	of	of	ADP
admet-641	17	45	pharmaceutical	pharmaceutical	ADJ
admet-641	17	46	cocrystals	cocrystal	NOUN
admet-641	17	47	doi	doi	NOUN
admet-641	17	48	:	:	PUNCT
admet-641	17	49	10.5599	10.5599	NUM
admet-641	17	50	/	/	SYM
admet-641	17	51	admet.641	admet.641	PROPN
admet-641	17	52	285	285	NUM
admet-641	17	53	controlled	control	VERB
admet-641	17	54	by	by	ADP
admet-641	17	55	a	a	DET
admet-641	17	56	hierarchical	hierarchical	ADJ
admet-641	17	57	organisation	organisation	NOUN
admet-641	17	58	of	of	ADP
admet-641	17	59	functional	functional	ADJ
admet-641	17	60	group	group	NOUN
admet-641	17	61	interactions	interaction	NOUN
admet-641	17	62	.	.	PUNCT
admet-641	18	1	thus	thus	ADV
admet-641	18	2	,	,	PUNCT
admet-641	18	3	the	the	DET
admet-641	18	4	energy	energy	NOUN
admet-641	18	5	of	of	ADP
admet-641	18	6	a	a	DET
admet-641	18	7	solid	solid	ADJ
admet-641	18	8	form	form	NOUN
admet-641	18	9	(	(	PUNCT
admet-641	18	10	e	e	NOUN
admet-641	18	11	)	)	PUNCT
admet-641	18	12	can	can	AUX
admet-641	18	13	be	be	AUX
admet-641	18	14	calculated	calculate	VERB
admet-641	18	15	by	by	ADP
admet-641	18	16	pairing	pair	VERB
admet-641	18	17	the	the	DET
admet-641	18	18	best	good	ADJ
admet-641	18	19	h	h	NOUN
admet-641	18	20	-	-	PUNCT
admet-641	18	21	bond	bond	NOUN
admet-641	18	22	donor	donor	NOUN
admet-641	18	23	with	with	ADP
admet-641	18	24	the	the	DET
admet-641	18	25	best	good	ADJ
admet-641	18	26	h	h	NOUN
admet-641	18	27	-	-	PUNCT
admet-641	18	28	bond	bond	NOUN
admet-641	18	29	acceptor	acceptor	NOUN
admet-641	18	30	,	,	PUNCT
admet-641	18	31	the	the	DET
admet-641	18	32	second	second	ADJ
admet-641	18	33	best	good	ADJ
admet-641	18	34	hbond	hbond	ADJ
admet-641	18	35	donor	donor	NOUN
admet-641	18	36	with	with	ADP
admet-641	18	37	the	the	DET
admet-641	18	38	second	second	ADJ
admet-641	18	39	best	good	ADJ
admet-641	18	40	h	h	NOUN
admet-641	18	41	-	-	PUNCT
admet-641	18	42	bond	bond	NOUN
admet-641	18	43	acceptor	acceptor	NOUN
admet-641	18	44	,	,	PUNCT
admet-641	18	45	and	and	CCONJ
admet-641	18	46	so	so	ADV
admet-641	18	47	on	on	ADV
admet-641	18	48	,	,	PUNCT
admet-641	18	49	until	until	SCONJ
admet-641	18	50	all	all	PRON
admet-641	18	51	of	of	ADP
admet-641	18	52	the	the	DET
admet-641	18	53	interaction	interaction	NOUN
admet-641	18	54	sites	site	NOUN
admet-641	18	55	(	(	PUNCT
admet-641	18	56	i	i	PROPN
admet-641	18	57	,	,	PUNCT
admet-641	18	58	j	j	PROPN
admet-641	18	59	)	)	PUNCT
admet-641	18	60	are	be	AUX
admet-641	18	61	satisfied	satisfied	ADJ
admet-641	18	62	(	(	PUNCT
admet-641	18	63	eq	eq	NOUN
admet-641	18	64	.	.	PROPN
admet-641	18	65	1	1	NUM
admet-641	18	66	)	)	PUNCT
admet-641	18	67	.	.	PUNCT
admet-641	19	1	i	i	PRON
admet-641	19	2	j	j	INTJ
admet-641	20	1	ij	ij	NUM
admet-641	20	2	e	e	NOUN
admet-641	20	3			NOUN
admet-641	20	4			VERB
admet-641	20	5			X
admet-641	20	6	(	(	PUNCT
admet-641	20	7	1	1	X
admet-641	20	8	)	)	PUNCT
admet-641	20	9	the	the	DET
admet-641	20	10	difference	difference	NOUN
admet-641	20	11	between	between	ADP
admet-641	20	12	the	the	DET
admet-641	20	13	interaction	interaction	NOUN
admet-641	20	14	site	site	NOUN
admet-641	20	15	pairing	pair	VERB
admet-641	20	16	energies	energy	NOUN
admet-641	20	17	of	of	ADP
admet-641	20	18	the	the	DET
admet-641	20	19	cocrystal	cocrystal	ADJ
admet-641	20	20	(	(	PUNCT
admet-641	20	21	ecc	ecc	PROPN
admet-641	20	22	)	)	PUNCT
admet-641	20	23	and	and	CCONJ
admet-641	20	24	the	the	DET
admet-641	20	25	two	two	NUM
admet-641	20	26	components	component	NOUN
admet-641	20	27	(	(	PUNCT
admet-641	20	28	e1	e1	PROPN
admet-641	20	29	and	and	CCONJ
admet-641	20	30	e2	e2	PROPN
admet-641	20	31	)	)	PUNCT
admet-641	20	32	is	be	AUX
admet-641	20	33	related	relate	VERB
admet-641	20	34	to	to	ADP
admet-641	20	35	the	the	DET
admet-641	20	36	cocrystallization	cocrystallization	NOUN
admet-641	20	37	probability	probability	NOUN
admet-641	20	38	(	(	PUNCT
admet-641	20	39	eq	eq	NOUN
admet-641	20	40	.	.	NOUN
admet-641	20	41	2	2	NUM
admet-641	20	42	)	)	PUNCT
admet-641	20	43	.	.	PUNCT
admet-641	21	1	1	1	NUM
admet-641	21	2	2cce	2cce	NUM
admet-641	21	3	e	e	NOUN
admet-641	21	4	ne	ne	PROPN
admet-641	21	5	me	me	VERB
admet-641	21	6			PROPN
admet-641	21	7			PROPN
admet-641	21	8			NOUN
admet-641	21	9	(	(	PUNCT
admet-641	21	10	2	2	NUM
admet-641	21	11	)	)	PUNCT
admet-641	21	12	where	where	SCONJ
admet-641	21	13	n	n	NOUN
admet-641	21	14	and	and	CCONJ
admet-641	21	15	m	m	VERB
admet-641	21	16	refer	refer	VERB
admet-641	21	17	to	to	ADP
admet-641	21	18	the	the	DET
admet-641	21	19	cocrystal	cocrystal	ADJ
admet-641	21	20	stoichiometry	stoichiometry	NOUN
admet-641	21	21	.	.	PUNCT
admet-641	22	1	the	the	DET
admet-641	22	2	method	method	NOUN
admet-641	22	3	is	be	AUX
admet-641	22	4	based	base	VERB
admet-641	22	5	on	on	ADP
admet-641	22	6	assumptions	assumption	NOUN
admet-641	22	7	that	that	PRON
admet-641	22	8	ignore	ignore	VERB
admet-641	22	9	all	all	DET
admet-641	22	10	geometrical	geometrical	ADJ
admet-641	22	11	aspects	aspect	NOUN
admet-641	22	12	of	of	ADP
admet-641	22	13	crystal	crystal	NOUN
admet-641	22	14	packing	packing	NOUN
admet-641	22	15	:	:	PUNCT
admet-641	22	16	(	(	PUNCT
admet-641	22	17	a	a	X
admet-641	22	18	)	)	PUNCT
admet-641	22	19	all	all	DET
admet-641	22	20	potential	potential	ADJ
admet-641	22	21	interactions	interaction	NOUN
admet-641	22	22	in	in	ADP
admet-641	22	23	the	the	DET
admet-641	22	24	crystalline	crystalline	NOUN
admet-641	22	25	solid	solid	NOUN
admet-641	22	26	are	be	AUX
admet-641	22	27	established	establish	VERB
admet-641	22	28	(	(	PUNCT
admet-641	22	29	b	b	X
admet-641	22	30	)	)	PUNCT
admet-641	22	31	all	all	DET
admet-641	22	32	h	h	NOUN
admet-641	22	33	-	-	PUNCT
admet-641	22	34	bond	bond	NOUN
admet-641	22	35	sites	site	NOUN
admet-641	22	36	on	on	ADP
admet-641	22	37	the	the	DET
admet-641	22	38	surface	surface	NOUN
admet-641	22	39	of	of	ADP
admet-641	22	40	a	a	DET
admet-641	22	41	molecule	molecule	NOUN
admet-641	22	42	are	be	AUX
admet-641	22	43	independent	independent	ADJ
admet-641	22	44	and	and	CCONJ
admet-641	22	45	free	free	ADJ
admet-641	22	46	to	to	PART
admet-641	22	47	interact	interact	VERB
admet-641	22	48	with	with	ADP
admet-641	22	49	any	any	DET
admet-641	22	50	other	other	ADJ
admet-641	22	51	site	site	NOUN
admet-641	22	52	in	in	ADP
admet-641	22	53	the	the	DET
admet-641	22	54	solid	solid	ADJ
admet-641	22	55	,	,	PUNCT
admet-641	22	56	(	(	PUNCT
admet-641	22	57	c	c	NOUN
admet-641	22	58	)	)	PUNCT
admet-641	22	59	steric	steric	ADJ
admet-641	22	60	constraints	constraint	NOUN
admet-641	22	61	on	on	ADP
admet-641	22	62	contacts	contact	NOUN
admet-641	22	63	are	be	AUX
admet-641	22	64	not	not	PART
admet-641	22	65	considered	consider	VERB
admet-641	22	66	,	,	PUNCT
admet-641	22	67	(	(	PUNCT
admet-641	22	68	d	d	X
admet-641	22	69	)	)	PUNCT
admet-641	22	70	cooperativity	cooperativity	NOUN
admet-641	22	71	between	between	ADP
admet-641	22	72	sites	site	NOUN
admet-641	22	73	is	be	AUX
admet-641	22	74	ignored	ignore	VERB
admet-641	22	75	.	.	PUNCT
admet-641	23	1	the	the	DET
admet-641	23	2	consequence	consequence	NOUN
admet-641	23	3	of	of	ADP
admet-641	23	4	these	these	DET
admet-641	23	5	approximations	approximation	NOUN
admet-641	23	6	is	be	AUX
admet-641	23	7	that	that	SCONJ
admet-641	23	8	the	the	DET
admet-641	23	9	method	method	NOUN
admet-641	23	10	offers	offer	VERB
admet-641	23	11	a	a	DET
admet-641	23	12	solution	solution	NOUN
admet-641	23	13	to	to	ADP
admet-641	23	14	the	the	DET
admet-641	23	15	problem	problem	NOUN
admet-641	23	16	of	of	ADP
admet-641	23	17	rapid	rapid	ADJ
admet-641	23	18	virtual	virtual	ADJ
admet-641	23	19	screening	screening	NOUN
admet-641	23	20	of	of	ADP
admet-641	23	21	large	large	ADJ
admet-641	23	22	compound	compound	NOUN
admet-641	23	23	libraries	library	NOUN
admet-641	23	24	.	.	PUNCT
admet-641	24	1	the	the	DET
admet-641	24	2	method	method	NOUN
admet-641	24	3	was	be	AUX
admet-641	24	4	initially	initially	ADV
admet-641	24	5	calibrated	calibrate	VERB
admet-641	24	6	by	by	ADP
admet-641	24	7	performing	perform	VERB
admet-641	24	8	calculations	calculation	NOUN
admet-641	24	9	on	on	ADP
admet-641	24	10	two	two	NUM
admet-641	24	11	apis	apis	ADJ
admet-641	24	12	with	with	ADP
admet-641	24	13	the	the	DET
admet-641	24	14	highest	high	ADJ
admet-641	24	15	number	number	NOUN
admet-641	24	16	of	of	ADP
admet-641	24	17	reported	report	VERB
admet-641	24	18	experimental	experimental	ADJ
admet-641	24	19	cocrystals	cocrystal	NOUN
admet-641	24	20	(	(	PUNCT
admet-641	24	21	caffeine	caffeine	NOUN
admet-641	24	22	and	and	CCONJ
admet-641	24	23	carbamazepine	carbamazepine	NOUN
admet-641	24	24	)	)	PUNCT
admet-641	24	25	and	and	CCONJ
admet-641	24	26	a	a	DET
admet-641	24	27	list	list	NOUN
admet-641	24	28	of	of	ADP
admet-641	24	29	nearly	nearly	ADV
admet-641	24	30	1,000	1,000	NUM
admet-641	24	31	potential	potential	ADJ
admet-641	24	32	coformers	coformer	NOUN
admet-641	24	33	,	,	PUNCT
admet-641	24	34	providing	provide	VERB
admet-641	24	35	a	a	DET
admet-641	24	36	validation	validation	NOUN
admet-641	24	37	of	of	ADP
admet-641	24	38	the	the	DET
admet-641	24	39	relationship	relationship	NOUN
admet-641	24	40	between	between	ADP
admet-641	24	41	the	the	DET
admet-641	24	42	value	value	NOUN
admet-641	24	43	of	of	ADP
admet-641	24	44	δe	δe	NOUN
admet-641	24	45	and	and	CCONJ
admet-641	24	46	the	the	DET
admet-641	24	47	probability	probability	NOUN
admet-641	24	48	of	of	ADP
admet-641	24	49	cocrystal	cocrystal	ADJ
admet-641	24	50	formation	formation	NOUN
admet-641	24	51	(	(	PUNCT
admet-641	24	52	fig.1	fig.1	PROPN
admet-641	24	53	)	)	PUNCT
admet-641	24	54	.	.	PUNCT
admet-641	25	1	figure	figure	NOUN
admet-641	25	2	1	1	NUM
admet-641	25	3	.	.	PUNCT
admet-641	26	1	recall	recall	NOUN
admet-641	26	2	plots	plot	NOUN
admet-641	26	3	for	for	ADP
admet-641	26	4	the	the	DET
admet-641	26	5	prediction	prediction	NOUN
admet-641	26	6	of	of	ADP
admet-641	26	7	1:1	1:1	NUM
admet-641	26	8	cocrystals	cocrystal	NOUN
admet-641	26	9	of	of	ADP
admet-641	26	10	caffeine	caffeine	NOUN
admet-641	26	11	(	(	PUNCT
admet-641	26	12	a	a	NOUN
admet-641	26	13	)	)	PUNCT
admet-641	26	14	and	and	CCONJ
admet-641	26	15	carbamazepine	carbamazepine	NOUN
admet-641	26	16	(	(	PUNCT
admet-641	26	17	b	b	NOUN
admet-641	26	18	)	)	PUNCT
admet-641	26	19	with	with	ADP
admet-641	26	20	849	849	NUM
admet-641	26	21	and	and	CCONJ
admet-641	26	22	860	860	NUM
admet-641	26	23	potential	potential	ADJ
admet-641	26	24	coformers	coformer	NOUN
admet-641	26	25	respectively	respectively	ADV
admet-641	26	26	.	.	PUNCT
admet-641	27	1	h	h	PROPN
admet-641	27	2	is	be	AUX
admet-641	27	3	the	the	DET
admet-641	27	4	fraction	fraction	NOUN
admet-641	27	5	of	of	ADP
admet-641	27	6	total	total	ADJ
admet-641	27	7	hits	hit	NOUN
admet-641	27	8	found	find	VERB
admet-641	27	9	plotted	plot	VERB
admet-641	27	10	as	as	ADP
admet-641	27	11	function	function	NOUN
admet-641	27	12	of	of	ADP
admet-641	27	13	the	the	DET
admet-641	27	14	fraction	fraction	NOUN
admet-641	27	15	of	of	ADP
admet-641	27	16	compounds	compound	NOUN
admet-641	27	17	screened	screen	VERB
admet-641	27	18	(	(	PUNCT
admet-641	27	19	n	n	CCONJ
admet-641	27	20	)	)	PUNCT
admet-641	27	21	.	.	PUNCT
admet-641	28	1	the	the	DET
admet-641	28	2	line	line	NOUN
admet-641	28	3	(	(	PUNCT
admet-641	28	4	r	r	NOUN
admet-641	28	5	)	)	PUNCT
admet-641	28	6	represents	represent	VERB
admet-641	28	7	probability	probability	NOUN
admet-641	28	8	of	of	ADP
admet-641	28	9	finding	find	VERB
admet-641	28	10	a	a	DET
admet-641	28	11	hit	hit	NOUN
admet-641	28	12	as	as	ADP
admet-641	28	13	the	the	DET
admet-641	28	14	result	result	NOUN
admet-641	28	15	of	of	ADP
admet-641	28	16	random	random	ADJ
admet-641	28	17	chance	chance	NOUN
admet-641	28	18	.	.	PUNCT
admet-641	29	1	(	(	PUNCT
admet-641	29	2	c	c	X
admet-641	29	3	)	)	PUNCT
admet-641	29	4	relationship	relationship	NOUN
admet-641	29	5	between	between	ADP
admet-641	29	6	the	the	DET
admet-641	29	7	probability	probability	NOUN
admet-641	29	8	of	of	ADP
admet-641	29	9	obtaining	obtain	VERB
admet-641	29	10	a	a	DET
admet-641	29	11	cocrystal	cocrystal	ADJ
admet-641	29	12	,	,	PUNCT
admet-641	29	13	p	p	X
admet-641	29	14	,	,	PUNCT
admet-641	29	15	and	and	CCONJ
admet-641	29	16	the	the	DET
admet-641	29	17	calculated	calculate	VERB
admet-641	29	18	cocrystal	cocrystal	ADJ
admet-641	29	19	energy	energy	NOUN
admet-641	29	20	,	,	PUNCT
admet-641	29	21	.	.	NUM
admet-641	29	22	in	in	ADP
admet-641	29	23	addition	addition	NOUN
admet-641	29	24	,	,	PUNCT
admet-641	29	25	a	a	DET
admet-641	29	26	set	set	NOUN
admet-641	29	27	of	of	ADP
admet-641	29	28	validations	validation	NOUN
admet-641	29	29	was	be	AUX
admet-641	29	30	conducted	conduct	VERB
admet-641	29	31	with	with	ADP
admet-641	29	32	cocrystal	cocrystal	ADJ
admet-641	29	33	screens	screen	NOUN
admet-641	29	34	of	of	ADP
admet-641	29	35	nine	nine	NUM
admet-641	29	36	apis	apis	ADJ
admet-641	29	37	from	from	ADP
admet-641	29	38	the	the	DET
admet-641	29	39	literature	literature	NOUN
admet-641	29	40	(	(	PUNCT
admet-641	29	41	diclofenac	diclofenac	NOUN
admet-641	29	42	,	,	PUNCT
admet-641	29	43	piracetam	piracetam	NOUN
admet-641	29	44	,	,	PUNCT
admet-641	29	45	pyrazine	pyrazine	NOUN
admet-641	29	46	carboxamide	carboxamide	NOUN
admet-641	29	47	,	,	PUNCT
admet-641	29	48	acetazolamide	acetazolamide	ADV
admet-641	29	49	,	,	PUNCT
admet-641	29	50	indomethacin	indomethacin	NOUN
admet-641	29	51	,	,	PUNCT
admet-641	29	52	furosemide	furosemide	ADJ
admet-641	29	53	,	,	PUNCT
admet-641	29	54	nalidixic	nalidixic	ADJ
admet-641	29	55	acid	acid	NOUN
admet-641	29	56	,	,	PUNCT
admet-641	29	57	prohens	prohen	NOUN
admet-641	29	58	and	and	CCONJ
admet-641	29	59	hunter	hunter	NOUN
admet-641	29	60	admet	admet	PROPN
admet-641	29	61	&	&	CCONJ
admet-641	29	62	dmpk	dmpk	PROPN
admet-641	29	63	6(4	6(4	PROPN
admet-641	29	64	)	)	PUNCT
admet-641	29	65	(	(	PUNCT
admet-641	29	66	2018	2018	NUM
admet-641	29	67	)	)	PUNCT
admet-641	29	68	284	284	NUM
admet-641	29	69	-	-	SYM
admet-641	29	70	287	287	NUM
admet-641	29	71	286	286	NUM
admet-641	29	72	paracetamol	paracetamol	NOUN
admet-641	29	73	and	and	CCONJ
admet-641	29	74	a	a	DET
admet-641	29	75	drug	drug	NOUN
admet-641	29	76	candidate	candidate	NOUN
admet-641	29	77	)	)	PUNCT
admet-641	29	78	that	that	PRON
admet-641	29	79	had	have	AUX
admet-641	29	80	reported	report	VERB
admet-641	29	81	both	both	CCONJ
admet-641	29	82	successful	successful	ADJ
admet-641	29	83	and	and	CCONJ
admet-641	29	84	unsuccessful	unsuccessful	ADJ
admet-641	29	85	coformers	coformer	NOUN
admet-641	29	86	,	,	PUNCT
admet-641	29	87	and	and	CCONJ
admet-641	29	88	in	in	ADP
admet-641	29	89	most	most	ADJ
admet-641	29	90	cases	case	NOUN
admet-641	29	91	,	,	PUNCT
admet-641	29	92	calculations	calculation	NOUN
admet-641	29	93	reproduced	reproduce	VERB
admet-641	29	94	the	the	DET
admet-641	29	95	experimental	experimental	ADJ
admet-641	29	96	results	result	NOUN
admet-641	29	97	[	[	X
admet-641	29	98	8	8	NUM
admet-641	29	99	]	]	PUNCT
admet-641	29	100	.	.	PUNCT
admet-641	30	1	the	the	DET
admet-641	30	2	method	method	NOUN
admet-641	30	3	has	have	AUX
admet-641	30	4	been	be	AUX
admet-641	30	5	further	far	ADV
admet-641	30	6	applied	apply	VERB
admet-641	30	7	in	in	ADP
admet-641	30	8	combination	combination	NOUN
admet-641	30	9	with	with	ADP
admet-641	30	10	experimental	experimental	ADJ
admet-641	30	11	screening	screening	NOUN
admet-641	30	12	techniques	technique	NOUN
admet-641	30	13	to	to	PART
admet-641	30	14	optimize	optimize	VERB
admet-641	30	15	the	the	DET
admet-641	30	16	search	search	NOUN
admet-641	30	17	for	for	ADP
admet-641	30	18	new	new	ADJ
admet-641	30	19	cocrystals	cocrystal	NOUN
admet-641	30	20	with	with	ADP
admet-641	30	21	improved	improve	VERB
admet-641	30	22	physicochemical	physicochemical	ADJ
admet-641	30	23	properties	property	NOUN
admet-641	30	24	of	of	ADP
admet-641	30	25	apis	apis	PROPN
admet-641	30	26	,	,	PUNCT
admet-641	30	27	such	such	ADJ
admet-641	30	28	as	as	ADP
admet-641	30	29	nalidixic	nalidixic	ADJ
admet-641	30	30	acid	acid	NOUN
admet-641	30	31	[	[	X
admet-641	30	32	9	9	NUM
admet-641	30	33	]	]	SYM
admet-641	30	34	spironolactone	spironolactone	NOUN
admet-641	30	35	,	,	PUNCT
admet-641	30	36	griseofulvin	griseofulvin	NOUN
admet-641	30	37	[	[	X
admet-641	30	38	10	10	NUM
admet-641	30	39	]	]	PUNCT
admet-641	30	40	,	,	PUNCT
admet-641	30	41	zafirlukast	zafirlukast	X
admet-641	31	1	[	[	X
admet-641	31	2	11	11	NUM
admet-641	31	3	]	]	PUNCT
admet-641	31	4	,	,	PUNCT
admet-641	31	5	sildenafil	sildenafil	NOUN
admet-641	31	6	[	[	X
admet-641	31	7	12,13	12,13	NUM
admet-641	31	8	]	]	PUNCT
admet-641	31	9	and	and	CCONJ
admet-641	31	10	a	a	DET
admet-641	31	11	novel	novel	NOUN
admet-641	31	12	inhaled	inhale	VERB
admet-641	31	13	jak	jak	PROPN
admet-641	31	14	-	-	PUNCT
admet-641	31	15	stat	stat	NOUN
admet-641	31	16	inhibitor	inhibitor	NOUN
admet-641	31	17	[	[	X
admet-641	31	18	14	14	NUM
admet-641	31	19	]	]	PUNCT
admet-641	31	20	.	.	PUNCT
admet-641	32	1	figure	figure	NOUN
admet-641	32	2	2	2	NUM
admet-641	32	3	.	.	PUNCT
admet-641	32	4	drug	drug	NOUN
admet-641	32	5	compounds	compound	NOUN
admet-641	32	6	tested	test	VERB
admet-641	32	7	in	in	ADP
admet-641	32	8	combined	combined	ADJ
admet-641	32	9	virtual	virtual	ADJ
admet-641	32	10	/	/	SYM
admet-641	32	11	experimental	experimental	ADJ
admet-641	32	12	cocrystal	cocrystal	ADJ
admet-641	32	13	screens	screen	NOUN
admet-641	32	14	virtual	virtual	ADJ
admet-641	32	15	cocrystal	cocrystal	ADJ
admet-641	32	16	screening	screening	NOUN
admet-641	32	17	for	for	ADP
admet-641	32	18	coformer	coformer	NOUN
admet-641	32	19	selection	selection	NOUN
admet-641	32	20	is	be	AUX
admet-641	32	21	just	just	ADV
admet-641	32	22	part	part	NOUN
admet-641	32	23	of	of	ADP
admet-641	32	24	the	the	DET
admet-641	32	25	more	more	ADV
admet-641	32	26	complicated	complicated	ADJ
admet-641	32	27	procedure	procedure	NOUN
admet-641	32	28	of	of	ADP
admet-641	32	29	cocrystal	cocrystal	ADJ
admet-641	32	30	investigation	investigation	NOUN
admet-641	32	31	in	in	ADP
admet-641	32	32	the	the	DET
admet-641	32	33	pharmaceutical	pharmaceutical	ADJ
admet-641	32	34	industry	industry	NOUN
admet-641	32	35	.	.	PUNCT
admet-641	33	1	thus	thus	ADV
admet-641	33	2	,	,	PUNCT
admet-641	33	3	other	other	ADJ
admet-641	33	4	pre	pre	ADJ
admet-641	33	5	-	-	ADJ
admet-641	33	6	screening	screen	VERB
admet-641	33	7	techniques	technique	NOUN
admet-641	33	8	must	must	AUX
admet-641	33	9	be	be	AUX
admet-641	33	10	applied	apply	VERB
admet-641	33	11	prior	prior	ADV
admet-641	33	12	to	to	ADP
admet-641	33	13	the	the	DET
admet-641	33	14	experimental	experimental	ADJ
admet-641	33	15	search	search	NOUN
admet-641	33	16	for	for	ADP
admet-641	33	17	new	new	ADJ
admet-641	33	18	cocrystals	cocrystal	NOUN
admet-641	33	19	in	in	ADP
admet-641	33	20	order	order	NOUN
admet-641	33	21	to	to	PART
admet-641	33	22	reduce	reduce	VERB
admet-641	33	23	time	time	NOUN
admet-641	33	24	and	and	CCONJ
admet-641	33	25	optimize	optimize	VERB
admet-641	33	26	resources	resource	NOUN
admet-641	33	27	.	.	PUNCT
admet-641	34	1	for	for	ADP
admet-641	34	2	instance	instance	NOUN
admet-641	34	3	,	,	PUNCT
admet-641	34	4	solubility	solubility	NOUN
admet-641	34	5	prediction	prediction	NOUN
admet-641	34	6	can	can	AUX
admet-641	34	7	also	also	ADV
admet-641	34	8	be	be	AUX
admet-641	34	9	conducted	conduct	VERB
admet-641	34	10	if	if	SCONJ
admet-641	34	11	an	an	DET
admet-641	34	12	increase	increase	NOUN
admet-641	34	13	/	/	SYM
admet-641	34	14	decrease	decrease	NOUN
admet-641	34	15	in	in	ADP
admet-641	34	16	solubility	solubility	NOUN
admet-641	34	17	is	be	AUX
admet-641	34	18	a	a	DET
admet-641	34	19	requirement	requirement	NOUN
admet-641	34	20	for	for	ADP
admet-641	34	21	the	the	DET
admet-641	34	22	formulation	formulation	NOUN
admet-641	35	1	[	[	X
admet-641	35	2	15	15	NUM
admet-641	35	3	]	]	PUNCT
admet-641	35	4	,	,	PUNCT
admet-641	35	5	and	and	CCONJ
admet-641	35	6	the	the	DET
admet-641	35	7	safety	safety	NOUN
admet-641	35	8	/	/	SYM
admet-641	35	9	toxicity	toxicity	NOUN
admet-641	35	10	profile	profile	NOUN
admet-641	35	11	of	of	ADP
admet-641	35	12	every	every	DET
admet-641	35	13	potential	potential	ADJ
admet-641	35	14	coformer	coformer	NOUN
admet-641	35	15	must	must	AUX
admet-641	35	16	be	be	AUX
admet-641	35	17	assessed	assess	VERB
admet-641	35	18	using	use	VERB
admet-641	35	19	databases	database	NOUN
admet-641	35	20	or	or	CCONJ
admet-641	35	21	in	in	ADP
admet-641	35	22	silico	silico	NOUN
admet-641	35	23	prediction	prediction	NOUN
admet-641	36	1	[	[	X
admet-641	36	2	16	16	NUM
admet-641	36	3	]	]	PUNCT
admet-641	36	4	.	.	PUNCT
admet-641	37	1	finally	finally	ADV
admet-641	37	2	,	,	PUNCT
admet-641	37	3	once	once	ADV
admet-641	37	4	all	all	DET
admet-641	37	5	the	the	DET
admet-641	37	6	computational	computational	ADJ
admet-641	37	7	work	work	NOUN
admet-641	37	8	is	be	AUX
admet-641	37	9	done	do	VERB
admet-641	37	10	,	,	PUNCT
admet-641	37	11	information	information	NOUN
admet-641	37	12	about	about	ADP
admet-641	37	13	the	the	DET
admet-641	37	14	solubility	solubility	NOUN
admet-641	37	15	of	of	ADP
admet-641	37	16	the	the	DET
admet-641	37	17	api	api	NOUN
admet-641	37	18	and	and	CCONJ
admet-641	37	19	the	the	DET
admet-641	37	20	chosen	choose	VERB
admet-641	37	21	coformers	coformer	NOUN
admet-641	37	22	in	in	ADP
admet-641	37	23	the	the	DET
admet-641	37	24	organic	organic	ADJ
admet-641	37	25	solvents	solvent	NOUN
admet-641	37	26	used	use	VERB
admet-641	37	27	for	for	ADP
admet-641	37	28	crystallisation	crystallisation	NOUN
admet-641	37	29	and	and	CCONJ
admet-641	37	30	about	about	ADP
admet-641	37	31	the	the	DET
admet-641	37	32	presence	presence	NOUN
admet-641	37	33	of	of	ADP
admet-641	37	34	polymorphism	polymorphism	NOUN
admet-641	37	35	/	/	SYM
admet-641	37	36	solvatomorphism	solvatomorphism	NOUN
admet-641	37	37	is	be	AUX
admet-641	37	38	necessary	necessary	ADJ
admet-641	37	39	.	.	PUNCT
admet-641	38	1	this	this	DET
admet-641	38	2	information	information	NOUN
admet-641	38	3	is	be	AUX
admet-641	38	4	essential	essential	ADJ
admet-641	38	5	for	for	ADP
admet-641	38	6	selection	selection	NOUN
admet-641	38	7	of	of	ADP
admet-641	38	8	the	the	DET
admet-641	38	9	experimental	experimental	ADJ
admet-641	38	10	conditions	condition	NOUN
admet-641	38	11	which	which	PRON
admet-641	38	12	will	will	AUX
admet-641	38	13	allow	allow	VERB
admet-641	38	14	the	the	DET
admet-641	38	15	most	most	ADV
admet-641	38	16	extensive	extensive	ADJ
admet-641	38	17	and	and	CCONJ
admet-641	38	18	efficient	efficient	ADJ
admet-641	38	19	exploration	exploration	NOUN
admet-641	38	20	of	of	ADP
admet-641	38	21	the	the	DET
admet-641	38	22	cocrystal	cocrystal	ADJ
admet-641	38	23	landscape	landscape	NOUN
admet-641	38	24	.	.	PUNCT
admet-641	39	1	in	in	ADP
admet-641	39	2	summary	summary	NOUN
admet-641	39	3	,	,	PUNCT
admet-641	39	4	the	the	DET
admet-641	39	5	use	use	NOUN
admet-641	39	6	of	of	ADP
admet-641	39	7	computational	computational	ADJ
admet-641	39	8	approaches	approach	NOUN
admet-641	39	9	together	together	ADV
admet-641	39	10	with	with	ADP
admet-641	39	11	experimental	experimental	ADJ
admet-641	39	12	screening	screening	NOUN
admet-641	39	13	methodologies	methodology	NOUN
admet-641	39	14	,	,	PUNCT
admet-641	39	15	if	if	SCONJ
admet-641	39	16	combined	combine	VERB
admet-641	39	17	efficiently	efficiently	ADV
admet-641	39	18	,	,	PUNCT
admet-641	39	19	can	can	AUX
admet-641	39	20	reduce	reduce	VERB
admet-641	39	21	the	the	DET
admet-641	39	22	time	time	NOUN
admet-641	39	23	and	and	CCONJ
admet-641	39	24	cost	cost	NOUN
admet-641	39	25	of	of	ADP
admet-641	39	26	the	the	DET
admet-641	39	27	development	development	NOUN
admet-641	39	28	of	of	ADP
admet-641	39	29	a	a	DET
admet-641	39	30	new	new	ADJ
admet-641	39	31	cocrystal	cocrystal	ADJ
admet-641	39	32	formulation	formulation	NOUN
admet-641	39	33	.	.	PUNCT
admet-641	40	1	references	reference	NOUN
admet-641	40	2	[	[	X
admet-641	40	3	1	1	X
admet-641	40	4	]	]	X
admet-641	40	5	g.r	g.r	PROPN
admet-641	40	6	.	.	PUNCT
admet-641	40	7	desiraju	desiraju	PROPN
admet-641	40	8	.	.	PUNCT
admet-641	41	1	supramolecular	supramolecular	ADJ
admet-641	41	2	synthons	synthon	NOUN
admet-641	41	3	in	in	ADP
admet-641	41	4	crystal	crystal	NOUN
admet-641	41	5	engineering	engineering	NOUN
admet-641	41	6	a	a	DET
admet-641	41	7	new	new	ADJ
admet-641	41	8	organic	organic	ADJ
admet-641	41	9	synthesis	synthesis	NOUN
admet-641	41	10	.	.	PUNCT
admet-641	42	1	angew	angew	PROPN
admet-641	42	2	.	.	PUNCT
admet-641	43	1	chem	chem	PROPN
admet-641	43	2	.	.	PUNCT
admet-641	44	1	int	int	NOUN
admet-641	44	2	.	.	PUNCT
admet-641	45	1	ed	ed	NOUN
admet-641	45	2	.	.	PROPN
admet-641	46	1	34	34	NUM
admet-641	46	2	(	(	PUNCT
admet-641	46	3	1995	1995	NUM
admet-641	46	4	)	)	PUNCT
admet-641	46	5	2311	2311	NUM
admet-641	46	6	-	-	SYM
admet-641	46	7	2327	2327	NUM
admet-641	46	8	.	.	PUNCT
admet-641	47	1	[	[	X
admet-641	47	2	2	2	NUM
admet-641	47	3	]	]	X
admet-641	47	4	m.a	m.a	PROPN
admet-641	47	5	.	.	PROPN
admet-641	47	6	mohammad	mohammad	PROPN
admet-641	47	7	,	,	PUNCT
admet-641	47	8	a.	a.	NOUN
admet-641	47	9	alhalaweh	alhalaweh	PROPN
admet-641	47	10	,	,	PUNCT
admet-641	47	11	s.p	s.p	PROPN
admet-641	47	12	.	.	PROPN
admet-641	47	13	velaga	velaga	PROPN
admet-641	47	14	.	.	PUNCT
admet-641	48	1	hansen	hansen	PROPN
admet-641	48	2	solubility	solubility	PROPN
admet-641	48	3	parameter	parameter	NOUN
admet-641	48	4	as	as	ADP
admet-641	48	5	a	a	DET
admet-641	48	6	tool	tool	NOUN
admet-641	48	7	to	to	PART
admet-641	48	8	predict	predict	VERB
admet-641	48	9	cocrystal	cocrystal	ADJ
admet-641	48	10	formation	formation	NOUN
admet-641	48	11	.	.	PUNCT
admet-641	49	1	int	int	NOUN
admet-641	49	2	.	.	PUNCT
admet-641	50	1	j.	j.	PROPN
admet-641	50	2	pharm	pharm	PROPN
admet-641	50	3	.	.	PUNCT
admet-641	51	1	407	407	NUM
admet-641	51	2	(	(	PUNCT
admet-641	51	3	2011	2011	NUM
admet-641	51	4	)	)	PUNCT
admet-641	51	5	63	63	NUM
admet-641	51	6	-	-	SYM
admet-641	51	7	71	71	NUM
admet-641	51	8	.	.	PUNCT
admet-641	52	1	[	[	X
admet-641	52	2	3	3	X
admet-641	52	3	]	]	X
admet-641	52	4	l.	l.	PROPN
admet-641	52	5	fabián	fabián	PROPN
admet-641	52	6	,	,	PUNCT
admet-641	52	7	cambridge	cambridge	PROPN
admet-641	52	8	structural	structural	ADJ
admet-641	52	9	database	database	NOUN
admet-641	52	10	analysis	analysis	NOUN
admet-641	52	11	of	of	ADP
admet-641	52	12	molecular	molecular	ADJ
admet-641	52	13	complementarity	complementarity	NOUN
admet-641	52	14	in	in	ADP
admet-641	52	15	cocrystals	cocrystal	NOUN
admet-641	52	16	.	.	PUNCT
admet-641	53	1	cryst	cryst	PROPN
admet-641	53	2	.	.	PUNCT
admet-641	54	1	growth	growth	PROPN
admet-641	54	2	des	des	PROPN
admet-641	54	3	.	.	PROPN
admet-641	54	4	9	9	NUM
admet-641	54	5	(	(	PUNCT
admet-641	54	6	2009	2009	NUM
admet-641	54	7	)	)	PUNCT
admet-641	54	8	1436–1443	1436–1443	NUM
admet-641	54	9	.	.	PUNCT
admet-641	55	1	[	[	X
admet-641	55	2	4	4	NUM
admet-641	55	3	]	]	PUNCT
admet-641	55	4	a.	a.	NOUN
admet-641	55	5	delori	delori	PROPN
admet-641	55	6	,	,	PUNCT
admet-641	55	7	p.t.a	p.t.a	ADJ
admet-641	55	8	.	.	PROPN
admet-641	55	9	galek	galek	PROPN
admet-641	55	10	,	,	PUNCT
admet-641	55	11	e.	e.	PROPN
admet-641	55	12	pidcock	pidcock	PROPN
admet-641	55	13	,	,	PUNCT
admet-641	55	14	m.	m.	NOUN
admet-641	55	15	patni	patni	PROPN
admet-641	55	16	,	,	PUNCT
admet-641	55	17	w.	w.	PROPN
admet-641	55	18	jones	jones	PROPN
admet-641	55	19	.	.	PUNCT
admet-641	56	1	knowledge	knowledge	NOUN
admet-641	56	2	-	-	PUNCT
admet-641	56	3	based	base	VERB
admet-641	56	4	hydrogen	hydrogen	NOUN
admet-641	56	5	bond	bond	NOUN
admet-641	56	6	prediction	prediction	NOUN
admet-641	56	7	and	and	CCONJ
admet-641	56	8	the	the	DET
admet-641	56	9	synthesis	synthesis	NOUN
admet-641	56	10	of	of	ADP
admet-641	56	11	salts	salt	NOUN
admet-641	56	12	and	and	CCONJ
admet-641	56	13	cocrystals	cocrystal	NOUN
admet-641	56	14	of	of	ADP
admet-641	56	15	the	the	DET
admet-641	56	16	anti	anti	ADJ
admet-641	56	17	-	-	ADJ
admet-641	56	18	malarial	malarial	ADJ
admet-641	56	19	drug	drug	NOUN
admet-641	56	20	pyrimethamine	pyrimethamine	NOUN
admet-641	56	21	with	with	ADP
admet-641	56	22	various	various	ADJ
admet-641	56	23	drug	drug	NOUN
admet-641	56	24	and	and	CCONJ
admet-641	56	25	gras	gras	PROPN
admet-641	56	26	molecules	molecule	NOUN
admet-641	56	27	.	.	PUNCT
admet-641	57	1	crystengcomm	crystengcomm	NOUN
admet-641	57	2	15	15	NUM
admet-641	57	3	(	(	PUNCT
admet-641	57	4	2013	2013	NUM
admet-641	57	5	)	)	PUNCT
admet-641	57	6	2916	2916	NUM
admet-641	57	7	-	-	SYM
admet-641	57	8	2928	2928	NUM
admet-641	57	9	.	.	PUNCT
admet-641	58	1	admet	admet	PROPN
admet-641	58	2	&	&	CCONJ
admet-641	58	3	dmpk	dmpk	PROPN
admet-641	58	4	6(4	6(4	PROPN
admet-641	58	5	)	)	PUNCT
admet-641	58	6	(	(	PUNCT
admet-641	58	7	2018	2018	NUM
admet-641	58	8	)	)	PUNCT
admet-641	58	9	284	284	NUM
admet-641	58	10	-	-	SYM
admet-641	58	11	287	287	NUM
admet-641	58	12	computational	computational	ADJ
admet-641	58	13	screens	screen	NOUN
admet-641	58	14	of	of	ADP
admet-641	58	15	pharmaceutical	pharmaceutical	ADJ
admet-641	58	16	cocrystals	cocrystal	NOUN
admet-641	58	17	doi	doi	NOUN
admet-641	58	18	:	:	PUNCT
admet-641	58	19	10.5599	10.5599	NUM
admet-641	58	20	/	/	SYM
admet-641	58	21	admet.641	admet.641	NUM
admet-641	58	22	287	287	NUM
admet-641	59	1	[	[	X
admet-641	59	2	5	5	NUM
admet-641	59	3	]	]	X
admet-641	59	4	c.r	c.r	PROPN
admet-641	59	5	.	.	PROPN
admet-641	59	6	taylor	taylor	PROPN
admet-641	59	7	,	,	PUNCT
admet-641	59	8	g.m	g.m	PROPN
admet-641	59	9	.	.	PROPN
admet-641	59	10	day	day	NOUN
admet-641	59	11	.	.	PUNCT
admet-641	60	1	evaluating	evaluate	VERB
admet-641	60	2	the	the	DET
admet-641	60	3	energetic	energetic	ADJ
admet-641	60	4	driving	driving	NOUN
admet-641	60	5	force	force	NOUN
admet-641	60	6	for	for	ADP
admet-641	60	7	cocrystal	cocrystal	ADJ
admet-641	60	8	formation	formation	NOUN
admet-641	60	9	.	.	PUNCT
admet-641	61	1	cryst	cryst	PROPN
admet-641	61	2	.	.	PUNCT
admet-641	62	1	growth	growth	PROPN
admet-641	62	2	des	des	PROPN
admet-641	62	3	.	.	PROPN
admet-641	62	4	18	18	NUM
admet-641	62	5	(	(	PUNCT
admet-641	62	6	2018	2018	NUM
admet-641	62	7	)	)	PUNCT
admet-641	62	8	892	892	NUM
admet-641	62	9	-	-	SYM
admet-641	62	10	904	904	NUM
admet-641	62	11	.	.	PUNCT
admet-641	63	1	[	[	X
admet-641	63	2	6	6	NUM
admet-641	63	3	]	]	X
admet-641	63	4	d.	d.	PROPN
admet-641	63	5	musumeci	musumeci	PROPN
admet-641	63	6	,	,	PUNCT
admet-641	63	7	c.a	c.a	PROPN
admet-641	63	8	.	.	PROPN
admet-641	63	9	hunter	hunter	PROPN
admet-641	63	10	,	,	PUNCT
admet-641	63	11	r.	r.	PROPN
admet-641	63	12	prohens	prohens	PROPN
admet-641	63	13	,	,	PUNCT
admet-641	63	14	s.	s.	PROPN
admet-641	63	15	scuderi	scuderi	PROPN
admet-641	63	16	,	,	PUNCT
admet-641	63	17	j.f	j.f	PROPN
admet-641	63	18	.	.	PROPN
admet-641	63	19	mccabe	mccabe	PROPN
admet-641	63	20	.	.	PUNCT
admet-641	64	1	virtual	virtual	ADJ
admet-641	64	2	cocrystal	cocrystal	ADJ
admet-641	64	3	screening	screening	NOUN
admet-641	64	4	.	.	PUNCT
admet-641	65	1	chem	chem	NOUN
admet-641	65	2	.	.	PUNCT
admet-641	66	1	sci	sci	PROPN
admet-641	66	2	.	.	PROPN
admet-641	66	3	2	2	NUM
admet-641	66	4	(	(	PUNCT
admet-641	66	5	2011	2011	NUM
admet-641	66	6	)	)	PUNCT
admet-641	66	7	883	883	NUM
admet-641	66	8	-	-	SYM
admet-641	66	9	890	890	NUM
admet-641	66	10	.	.	PUNCT
admet-641	67	1	[	[	X
admet-641	67	2	7	7	NUM
admet-641	67	3	]	]	X
admet-641	67	4	c.a	c.a	PROPN
admet-641	67	5	.	.	PROPN
admet-641	67	6	hunter	hunter	PROPN
admet-641	67	7	.	.	PUNCT
admet-641	68	1	quantifying	quantify	VERB
admet-641	68	2	intermolecular	intermolecular	ADJ
admet-641	68	3	interactions	interaction	NOUN
admet-641	68	4	:	:	PUNCT
admet-641	68	5	guidelines	guideline	NOUN
admet-641	68	6	for	for	ADP
admet-641	68	7	the	the	DET
admet-641	68	8	molecular	molecular	ADJ
admet-641	68	9	recognition	recognition	NOUN
admet-641	68	10	toolbox	toolbox	NOUN
admet-641	68	11	.	.	PUNCT
admet-641	69	1	angew	angew	PROPN
admet-641	69	2	.	.	PUNCT
admet-641	70	1	chem	chem	PROPN
admet-641	70	2	.	.	PUNCT
admet-641	71	1	int	int	NOUN
admet-641	71	2	.	.	PUNCT
admet-641	72	1	ed	ed	NOUN
admet-641	72	2	.	.	PROPN
admet-641	73	1	43	43	NUM
admet-641	73	2	(	(	PUNCT
admet-641	73	3	2004	2004	NUM
admet-641	73	4	)	)	PUNCT
admet-641	74	1	5310–5324	5310–5324	NUM
admet-641	74	2	.	.	PUNCT
admet-641	75	1	[	[	X
admet-641	75	2	8	8	NUM
admet-641	75	3	]	]	PUNCT
admet-641	75	4	t.	t.	PROPN
admet-641	75	5	grecu	grecu	PROPN
admet-641	75	6	,	,	PUNCT
admet-641	75	7	c.a	c.a	PROPN
admet-641	75	8	.	.	PROPN
admet-641	75	9	hunter	hunter	PROPN
admet-641	75	10	,	,	PUNCT
admet-641	75	11	e.j	e.j	PROPN
admet-641	75	12	.	.	PROPN
admet-641	75	13	gardiner	gardiner	PROPN
admet-641	75	14	,	,	PUNCT
admet-641	75	15	j.f	j.f	PROPN
admet-641	75	16	.	.	PROPN
admet-641	75	17	mccabe	mccabe	PROPN
admet-641	75	18	.	.	PUNCT
admet-641	76	1	validation	validation	NOUN
admet-641	76	2	of	of	ADP
admet-641	76	3	a	a	DET
admet-641	76	4	computational	computational	ADJ
admet-641	76	5	cocrystal	cocrystal	ADJ
admet-641	76	6	prediction	prediction	NOUN
admet-641	76	7	tool	tool	NOUN
admet-641	76	8	:	:	PUNCT
admet-641	76	9	comparison	comparison	NOUN
admet-641	76	10	of	of	ADP
admet-641	76	11	virtual	virtual	ADJ
admet-641	76	12	and	and	CCONJ
admet-641	76	13	experimental	experimental	ADJ
admet-641	76	14	cocrystal	cocrystal	ADJ
admet-641	76	15	screening	screening	NOUN
admet-641	76	16	results	result	NOUN
admet-641	76	17	.	.	PUNCT
admet-641	77	1	cryst	cryst	ADJ
admet-641	77	2	.	.	PUNCT
admet-641	78	1	growth	growth	PROPN
admet-641	78	2	des	des	PROPN
admet-641	78	3	.	.	PROPN
admet-641	78	4	14	14	NUM
admet-641	78	5	(	(	PUNCT
admet-641	78	6	2014	2014	NUM
admet-641	78	7	)	)	PUNCT
admet-641	78	8	165–171	165–171	NUM
admet-641	78	9	.	.	PUNCT
admet-641	79	1	[	[	X
admet-641	79	2	9	9	NUM
admet-641	79	3	]	]	PUNCT
admet-641	79	4	t.	t.	PROPN
admet-641	79	5	grecu	grecu	PROPN
admet-641	79	6	,	,	PUNCT
admet-641	79	7	h.	h.	PROPN
admet-641	79	8	adams	adams	PROPN
admet-641	79	9	,	,	PUNCT
admet-641	79	10	c.a	c.a	PROPN
admet-641	79	11	.	.	PROPN
admet-641	79	12	hunter	hunter	PROPN
admet-641	79	13	,	,	PUNCT
admet-641	79	14	j.f	j.f	PROPN
admet-641	79	15	.	.	PROPN
admet-641	79	16	mccabe	mccabe	PROPN
admet-641	79	17	,	,	PUNCT
admet-641	79	18	a.	a.	NOUN
admet-641	79	19	portell	portell	PROPN
admet-641	79	20	,	,	PUNCT
admet-641	79	21	r.	r.	PROPN
admet-641	79	22	prohens	prohens	PROPN
admet-641	79	23	.	.	PUNCT
admet-641	80	1	virtual	virtual	ADJ
admet-641	80	2	screening	screening	NOUN
admet-641	80	3	identifies	identify	VERB
admet-641	80	4	new	new	ADJ
admet-641	80	5	cocrystals	cocrystal	NOUN
admet-641	80	6	of	of	ADP
admet-641	80	7	nalidixic	nalidixic	ADJ
admet-641	80	8	acid	acid	NOUN
admet-641	80	9	.	.	PUNCT
admet-641	81	1	cryst	cryst	PROPN
admet-641	81	2	.	.	PUNCT
admet-641	82	1	growth	growth	PROPN
admet-641	82	2	des	des	PROPN
admet-641	82	3	.	.	PROPN
admet-641	82	4	14	14	NUM
admet-641	82	5	(	(	PUNCT
admet-641	82	6	2014	2014	NUM
admet-641	82	7	)	)	PUNCT
admet-641	82	8	1749–1755	1749–1755	NUM
admet-641	82	9	.	.	PUNCT
admet-641	83	1	[	[	X
admet-641	83	2	10	10	NUM
admet-641	83	3	]	]	PUNCT
admet-641	83	4	t.	t.	PROPN
admet-641	83	5	grecu	grecu	PROPN
admet-641	83	6	,	,	PUNCT
admet-641	83	7	r.	r.	PROPN
admet-641	83	8	prohens	prohens	PROPN
admet-641	83	9	,	,	PUNCT
admet-641	83	10	j.f	j.f	PROPN
admet-641	83	11	.	.	PROPN
admet-641	83	12	mccabe	mccabe	PROPN
admet-641	83	13	,	,	PUNCT
admet-641	83	14	e.j	e.j	PROPN
admet-641	83	15	.	.	PROPN
admet-641	83	16	carrington	carrington	PROPN
admet-641	83	17	,	,	PUNCT
admet-641	83	18	j.s	j.s	PROPN
admet-641	83	19	.	.	PROPN
admet-641	83	20	wright	wright	PROPN
admet-641	83	21	,	,	PUNCT
admet-641	83	22	l.	l.	PROPN
admet-641	83	23	brammer	brammer	PROPN
admet-641	83	24	,	,	PUNCT
admet-641	83	25	c.a	c.a	PROPN
admet-641	83	26	.	.	PROPN
admet-641	83	27	hunter	hunter	PROPN
admet-641	83	28	.	.	PUNCT
admet-641	84	1	cocrystals	cocrystal	NOUN
admet-641	84	2	of	of	ADP
admet-641	84	3	spironolactone	spironolactone	NOUN
admet-641	84	4	and	and	CCONJ
admet-641	84	5	griseofulvin	griseofulvin	NOUN
admet-641	84	6	based	base	VERB
admet-641	84	7	on	on	ADP
admet-641	84	8	an	an	DET
admet-641	84	9	in	in	ADP
admet-641	84	10	silico	silico	NOUN
admet-641	84	11	screening	screen	VERB
admet-641	84	12	method	method	NOUN
admet-641	84	13	.	.	PUNCT
admet-641	85	1	crystengcomm	crystengcomm	NOUN
admet-641	85	2	19	19	NUM
admet-641	85	3	(	(	PUNCT
admet-641	85	4	2017	2017	NUM
admet-641	85	5	)	)	PUNCT
admet-641	85	6	3592	3592	NUM
admet-641	85	7	-	-	SYM
admet-641	85	8	3599	3599	NUM
admet-641	85	9	.	.	PUNCT
admet-641	86	1	[	[	X
admet-641	86	2	11	11	NUM
admet-641	86	3	]	]	PUNCT
admet-641	86	4	a.	a.	NOUN
admet-641	86	5	llinas	llinas	PROPN
admet-641	86	6	,	,	PUNCT
admet-641	86	7	r.	r.	PROPN
admet-641	86	8	barbas	barbas	PROPN
admet-641	86	9	,	,	PUNCT
admet-641	86	10	m.	m.	NOUN
admet-641	86	11	font	font	NOUN
admet-641	86	12	-	-	PUNCT
admet-641	86	13	bardia	bardia	NOUN
admet-641	86	14	,	,	PUNCT
admet-641	86	15	m.	m.	NOUN
admet-641	86	16	j.	j.	PROPN
admet-641	86	17	quayle	quayle	PROPN
admet-641	86	18	,	,	PUNCT
admet-641	86	19	s.	s.	PROPN
admet-641	86	20	velaga	velaga	PROPN
admet-641	86	21	,	,	PUNCT
admet-641	86	22	r.	r.	PROPN
admet-641	86	23	prohens	prohens	PROPN
admet-641	86	24	.	.	PUNCT
admet-641	87	1	two	two	NUM
admet-641	87	2	new	new	ADJ
admet-641	87	3	polymorphic	polymorphic	ADJ
admet-641	87	4	cocrystals	cocrystal	NOUN
admet-641	87	5	of	of	ADP
admet-641	87	6	zafirlukast	zafirlukast	NOUN
admet-641	87	7	:	:	PUNCT
admet-641	87	8	preparation	preparation	NOUN
admet-641	87	9	,	,	PUNCT
admet-641	87	10	crystal	crystal	NOUN
admet-641	87	11	structure	structure	NOUN
admet-641	87	12	,	,	PUNCT
admet-641	87	13	and	and	CCONJ
admet-641	87	14	stability	stability	NOUN
admet-641	87	15	relations	relation	NOUN
admet-641	87	16	.	.	PUNCT
admet-641	88	1	cryst	cryst	PROPN
admet-641	88	2	.	.	PUNCT
admet-641	89	1	growth	growth	PROPN
admet-641	89	2	des	des	PROPN
admet-641	89	3	.	.	PROPN
admet-641	89	4	15	15	NUM
admet-641	89	5	(	(	PUNCT
admet-641	89	6	2015	2015	NUM
admet-641	89	7	)	)	PUNCT
admet-641	89	8	4162	4162	NUM
admet-641	89	9	-	-	SYM
admet-641	89	10	4169	4169	NUM
admet-641	89	11	.	.	PUNCT
admet-641	90	1	[	[	X
admet-641	90	2	12	12	NUM
admet-641	90	3	]	]	X
admet-641	90	4	p.	p.	PROPN
admet-641	90	5	lawton	lawton	PROPN
admet-641	90	6	,	,	PUNCT
admet-641	90	7	h.	h.	PROPN
admet-641	90	8	l.	l.	PROPN
admet-641	90	9	jones	jones	PROPN
admet-641	90	10	,	,	PUNCT
admet-641	90	11	n.m	n.m	PROPN
admet-641	90	12	.	.	PROPN
admet-641	90	13	kanji	kanji	PROPN
admet-641	90	14	,	,	PUNCT
admet-641	90	15	r.	r.	PROPN
admet-641	90	16	barbas	barbas	PROPN
admet-641	90	17	,	,	PUNCT
admet-641	90	18	r.	r.	PROPN
admet-641	90	19	prohens	prohens	PROPN
admet-641	90	20	.	.	PUNCT
admet-641	91	1	pct	pct	NOUN
admet-641	91	2	/	/	SYM
admet-641	91	3	gb2017/050921	gb2017/050921	PROPN
admet-641	91	4	.	.	PUNCT
admet-641	92	1	[	[	X
admet-641	92	2	13	13	NUM
admet-641	92	3	]	]	X
admet-641	92	4	r.	r.	PROPN
admet-641	92	5	barbas	barbas	PROPN
admet-641	92	6	,	,	PUNCT
admet-641	92	7	m.	m.	NOUN
admet-641	92	8	font	font	NOUN
admet-641	92	9	-	-	PUNCT
admet-641	92	10	bardia	bardia	NOUN
admet-641	92	11	,	,	PUNCT
admet-641	92	12	a.	a.	NOUN
admet-641	92	13	paradkar	paradkar	PROPN
admet-641	92	14	,	,	PUNCT
admet-641	92	15	c.a	c.a	PROPN
admet-641	92	16	.	.	PROPN
admet-641	92	17	hunter	hunter	PROPN
admet-641	92	18	,	,	PUNCT
admet-641	92	19	r.	r.	PROPN
admet-641	92	20	prohens	prohens	PROPN
admet-641	92	21	.	.	PUNCT
admet-641	93	1	combined	combine	VERB
admet-641	93	2	virtual	virtual	ADJ
admet-641	93	3	/	/	SYM
admet-641	93	4	experimental	experimental	ADJ
admet-641	93	5	multicomponent	multicomponent	NOUN
admet-641	93	6	solid	solid	ADJ
admet-641	93	7	forms	form	NOUN
admet-641	93	8	screening	screen	VERB
admet-641	93	9	of	of	ADP
admet-641	93	10	sildenafil	sildenafil	NOUN
admet-641	93	11	:	:	PUNCT
admet-641	93	12	new	new	ADJ
admet-641	93	13	salts	salt	NOUN
admet-641	93	14	,	,	PUNCT
admet-641	93	15	cocrystals	cocrystal	NOUN
admet-641	93	16	,	,	PUNCT
admet-641	93	17	and	and	CCONJ
admet-641	93	18	hybrid	hybrid	ADJ
admet-641	93	19	salt	salt	NOUN
admet-641	93	20	–	–	PUNCT
admet-641	93	21	cocrystals	cocrystal	NOUN
admet-641	93	22	.	.	PUNCT
admet-641	94	1	cryst	cryst	PROPN
admet-641	94	2	.	.	PUNCT
admet-641	95	1	growth	growth	PROPN
admet-641	95	2	des	des	PROPN
admet-641	95	3	.	.	PROPN
admet-641	95	4	(	(	PUNCT
admet-641	95	5	2018	2018	NUM
admet-641	95	6	)	)	PUNCT
admet-641	95	7	in	in	ADP
admet-641	95	8	press	press	NOUN
admet-641	95	9	:	:	PUNCT
admet-641	95	10	doi	doi	NOUN
admet-641	95	11	:	:	PUNCT
admet-641	95	12	10.1021	10.1021	NUM
admet-641	95	13	/	/	SYM
admet-641	95	14	acs.cgd.8b01413	acs.cgd.8b01413	PROPN
admet-641	95	15	.	.	PUNCT
admet-641	96	1	[	[	X
admet-641	96	2	14	14	NUM
admet-641	96	3	]	]	PUNCT
admet-641	96	4	a.	a.	NOUN
admet-641	96	5	llinas	llinas	PROPN
admet-641	96	6	,	,	PUNCT
admet-641	96	7	r.	r.	PROPN
admet-641	96	8	barbas	barbas	PROPN
admet-641	96	9	,	,	PUNCT
admet-641	96	10	m.	m.	NOUN
admet-641	96	11	font	font	NOUN
admet-641	96	12	-	-	PUNCT
admet-641	96	13	bardia	bardia	NOUN
admet-641	96	14	,	,	PUNCT
admet-641	96	15	a.	a.	NOUN
admet-641	96	16	smailagic	smailagic	PROPN
admet-641	96	17	,	,	PUNCT
admet-641	96	18	r.	r.	PROPN
admet-641	96	19	prohens	prohens	PROPN
admet-641	96	20	.	.	PUNCT
admet-641	97	1	derisking	deriske	VERB
admet-641	97	2	development	development	NOUN
admet-641	97	3	by	by	ADP
admet-641	97	4	cocrystallisation	cocrystallisation	NOUN
admet-641	97	5	screen	screen	NOUN
admet-641	97	6	of	of	ADP
admet-641	97	7	a	a	DET
admet-641	97	8	novel	novel	ADJ
admet-641	97	9	selective	selective	ADJ
admet-641	97	10	inhaled	inhale	VERB
admet-641	97	11	jak	jak	PROPN
admet-641	97	12	-	-	PUNCT
admet-641	97	13	stat	stat	PROPN
admet-641	97	14	inhibitor	inhibitor	NOUN
admet-641	97	15	.	.	PUNCT
admet-641	98	1	cryst	cryst	PROPN
admet-641	98	2	.	.	PUNCT
admet-641	99	1	growth	growth	PROPN
admet-641	99	2	des	des	PROPN
admet-641	99	3	.	.	PROPN
admet-641	99	4	(	(	PUNCT
admet-641	99	5	2018	2018	NUM
admet-641	99	6	)	)	PUNCT
admet-641	99	7	in	in	ADP
admet-641	99	8	press	press	NOUN
admet-641	99	9	:	:	PUNCT
admet-641	99	10	doi	doi	NOUN
admet-641	99	11	:	:	PUNCT
admet-641	99	12	10.1021	10.1021	NUM
admet-641	99	13	/	/	SYM
admet-641	99	14	acs.cgd.8b01492	acs.cgd.8b01492	NOUN
admet-641	99	15	.	.	PUNCT
admet-641	100	1	[	[	X
admet-641	100	2	15	15	NUM
admet-641	100	3	]	]	X
admet-641	100	4	c.a	c.a	PROPN
admet-641	100	5	.	.	PROPN
admet-641	100	6	hunter	hunter	PROPN
admet-641	100	7	,	,	PUNCT
admet-641	100	8	r.	r.	PROPN
admet-641	100	9	prohens	prohens	PROPN
admet-641	100	10	.	.	PUNCT
admet-641	101	1	solid	solid	ADJ
admet-641	101	2	form	form	NOUN
admet-641	101	3	and	and	CCONJ
admet-641	101	4	solubility	solubility	NOUN
admet-641	101	5	.	.	PUNCT
admet-641	102	1	crystengcomm	crystengcomm	NOUN
admet-641	102	2	19	19	NUM
admet-641	102	3	(	(	PUNCT
admet-641	102	4	2017	2017	NUM
admet-641	102	5	)	)	PUNCT
admet-641	102	6	23	23	NUM
admet-641	102	7	-	-	SYM
admet-641	102	8	26	26	NUM
admet-641	102	9	.	.	PUNCT
admet-641	103	1	[	[	X
admet-641	103	2	16	16	NUM
admet-641	103	3	]	]	X
admet-641	103	4	p.a	p.a	PROPN
admet-641	103	5	.	.	PROPN
admet-641	103	6	corner	corner	PROPN
admet-641	103	7	,	,	PUNCT
admet-641	103	8	d.	d.	PROPN
admet-641	103	9	berry	berry	PROPN
admet-641	103	10	,	,	PUNCT
admet-641	103	11	j.f	j.f	PROPN
admet-641	103	12	.	.	PROPN
admet-641	103	13	mccabe	mccabe	PROPN
admet-641	103	14	,	,	PUNCT
admet-641	103	15	r.	r.	PROPN
admet-641	103	16	barbas	barbas	PROPN
admet-641	103	17	,	,	PUNCT
admet-641	103	18	r.	r.	PROPN
admet-641	103	19	prohens	prohens	PROPN
admet-641	103	20	,	,	PUNCT
admet-641	103	21	h.	h.	PROPN
admet-641	103	22	du	du	PROPN
admet-641	103	23	,	,	PUNCT
admet-641	103	24	h.	h.	PROPN
admet-641	103	25	zhou	zhou	PROPN
admet-641	103	26	,	,	PUNCT
admet-641	103	27	a.	a.	NOUN
admet-641	103	28	llinas	llinas	PROPN
admet-641	103	29	.	.	PUNCT
admet-641	104	1	property	property	NOUN
admet-641	104	2	prediction	prediction	NOUN
admet-641	104	3	and	and	CCONJ
admet-641	104	4	pharmacokinetic	pharmacokinetic	ADJ
admet-641	104	5	evaluation	evaluation	NOUN
admet-641	104	6	of	of	ADP
admet-641	104	7	mixed	mixed	ADJ
admet-641	104	8	stoichiometry	stoichiometry	NOUN
admet-641	104	9	cocrystals	cocrystal	NOUN
admet-641	104	10	of	of	ADP
admet-641	104	11	zafirlukast	zafirlukast	NOUN
admet-641	104	12	,	,	PUNCT
admet-641	104	13	a	a	DET
admet-641	104	14	drug	drug	NOUN
admet-641	104	15	delivery	delivery	NOUN
admet-641	104	16	case	case	NOUN
admet-641	104	17	study	study	NOUN
admet-641	104	18	.	.	PUNCT
admet-641	105	1	crystengcomm	crystengcomm	NOUN
admet-641	105	2	20	20	NUM
admet-641	105	3	(	(	PUNCT
admet-641	105	4	2018	2018	NUM
admet-641	105	5	)	)	PUNCT
admet-641	105	6	1346	1346	NUM
admet-641	105	7	-	-	SYM
admet-641	105	8	1351	1351	NUM
admet-641	105	9	.	.	PUNCT
admet-641	106	1	©	©	PROPN
admet-641	106	2	2018	2018	NUM
admet-641	106	3	by	by	ADP
admet-641	106	4	the	the	DET
admet-641	106	5	authors	author	NOUN
admet-641	106	6	;	;	PUNCT
admet-641	107	1	licensee	licensee	PROPN
admet-641	107	2	iapc	iapc	PROPN
admet-641	107	3	,	,	PUNCT
admet-641	107	4	zagreb	zagreb	PROPN
admet-641	107	5	,	,	PUNCT
admet-641	107	6	croatia	croatia	PROPN
admet-641	107	7	.	.	PUNCT
admet-641	108	1	this	this	DET
admet-641	108	2	article	article	NOUN
admet-641	108	3	is	be	AUX
admet-641	108	4	an	an	DET
admet-641	108	5	open	open	ADJ
admet-641	108	6	-	-	PUNCT
admet-641	108	7	access	access	NOUN
admet-641	108	8	article	article	NOUN
admet-641	108	9	distributed	distribute	VERB
admet-641	108	10	under	under	ADP
admet-641	108	11	the	the	DET
admet-641	108	12	terms	term	NOUN
admet-641	108	13	and	and	CCONJ
admet-641	108	14	conditions	condition	NOUN
admet-641	108	15	of	of	ADP
admet-641	108	16	the	the	DET
admet-641	108	17	creative	creative	ADJ
admet-641	108	18	commons	common	NOUN
admet-641	108	19	attribution	attribution	NOUN
admet-641	108	20	license	license	NOUN
admet-641	108	21	(	(	PUNCT
admet-641	108	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-641	108	23	)	)	PUNCT
admet-641	108	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN