id	sid	tid	token	lemma	pos
admet-698	1	1	multi	multi	ADJ
admet-698	1	2	-	-	ADJ
admet-698	1	3	lab	lab	ADJ
admet-698	1	4	intrinsic	intrinsic	ADJ
admet-698	1	5	solubility	solubility	NOUN
admet-698	1	6	measurement	measurement	NOUN
admet-698	1	7	reproducibility	reproducibility	NOUN
admet-698	1	8	in	in	ADP
admet-698	1	9	cheqsol	cheqsol	NOUN
admet-698	1	10	and	and	CCONJ
admet-698	1	11	shake	shake	NOUN
admet-698	1	12	-	-	PUNCT
admet-698	1	13	flask	flask	NOUN
admet-698	1	14	methods	method	NOUN
admet-698	1	15	doi	doi	NOUN
admet-698	1	16	:	:	PUNCT
admet-698	1	17	10.5599	10.5599	NUM
admet-698	1	18	/	/	SYM
admet-698	1	19	admet.698	admet.698	ADJ
admet-698	1	20	210	210	NUM
admet-698	1	21	admet	admet	X
admet-698	1	22	&	&	CCONJ
admet-698	1	23	dmpk	dmpk	PROPN
admet-698	1	24	7(3	7(3	NUM
admet-698	1	25	)	)	PUNCT
admet-698	1	26	(	(	PUNCT
admet-698	1	27	2019)210	2019)210	PROPN
admet-698	1	28	-	-	PUNCT
admet-698	1	29	219	219	NUM
admet-698	1	30	doi	doi	NOUN
admet-698	1	31	:	:	PUNCT
admet-698	1	32	http://dx.doi.org/10.5599/admet.698	http://dx.doi.org/10.5599/admet.698	NOUN
admet-698	1	33	open	open	ADJ
admet-698	1	34	access	access	NOUN
admet-698	1	35	:	:	PUNCT
admet-698	1	36	issn	issn	PROPN
admet-698	1	37	:	:	PUNCT
admet-698	1	38	1848	1848	NUM
admet-698	1	39	-	-	SYM
admet-698	1	40	7718	7718	NUM
admet-698	1	41	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-698	1	42	short	short	ADJ
admet-698	1	43	communication	communication	NOUN
admet-698	1	44	multi	multi	ADJ
admet-698	1	45	-	-	ADJ
admet-698	1	46	lab	lab	ADJ
admet-698	1	47	intrinsic	intrinsic	ADJ
admet-698	1	48	solubility	solubility	NOUN
admet-698	1	49	measurement	measurement	NOUN
admet-698	1	50	reproducibility	reproducibility	NOUN
admet-698	1	51	in	in	ADP
admet-698	1	52	cheqsol	cheqsol	NOUN
admet-698	1	53	and	and	CCONJ
admet-698	1	54	shake	shake	NOUN
admet-698	1	55	-	-	PUNCT
admet-698	1	56	flask	flask	NOUN
admet-698	1	57	methods	method	NOUN
admet-698	1	58	alex	alex	PROPN
admet-698	1	59	avdeef	avdeef	PROPN
admet-698	1	60	in	in	ADP
admet-698	1	61	-	-	PUNCT
admet-698	1	62	adme	adme	NOUN
admet-698	1	63	research	research	NOUN
admet-698	1	64	,	,	PUNCT
admet-698	1	65	1732	1732	NUM
admet-698	1	66	first	first	ADJ
admet-698	1	67	avenue	avenue	PROPN
admet-698	1	68	,	,	PUNCT
admet-698	1	69	#	#	SYM
admet-698	1	70	102	102	NUM
admet-698	1	71	,	,	PUNCT
admet-698	1	72	new	new	PROPN
admet-698	1	73	york	york	PROPN
admet-698	1	74	,	,	PUNCT
admet-698	1	75	ny	ny	PROPN
admet-698	1	76	10128	10128	NUM
admet-698	1	77	,	,	PUNCT
admet-698	1	78	usa	usa	PROPN
admet-698	1	79	corresponding	corresponding	PROPN
admet-698	1	80	author	author	NOUN
admet-698	1	81	e	e	NOUN
admet-698	1	82	-	-	NOUN
admet-698	1	83	mail	mail	NOUN
admet-698	1	84	:	:	PUNCT
admet-698	1	85	alex@in-adme.com	alex@in-adme.com	NOUN
admet-698	1	86	;	;	PUNCT
admet-698	1	87	tel	tel	PROPN
admet-698	1	88	.	.	PUNCT
admet-698	1	89	:	:	PUNCT
admet-698	2	1	+1	+1	PROPN
admet-698	2	2	-	-	PUNCT
admet-698	2	3	646	646	NUM
admet-698	2	4	-	-	PUNCT
admet-698	2	5	678	678	NUM
admet-698	2	6	-	-	SYM
admet-698	2	7	5713	5713	NUM
admet-698	2	8	,	,	PUNCT
admet-698	2	9	orcid	orcid	NOUN
admet-698	3	1	i	i	NOUN
admet-698	3	2	d	d	PROPN
admet-698	3	3	:	:	PUNCT
admet-698	3	4	alex	alex	PROPN
admet-698	3	5	avdeef	avdeef	PROPN
admet-698	3	6	:	:	PUNCT
admet-698	3	7	0000	0000	NUM
admet-698	3	8	-	-	PUNCT
admet-698	3	9	0002	0002	NUM
admet-698	3	10	-	-	SYM
admet-698	3	11	31395442	31395442	NUM
admet-698	3	12	received	receive	VERB
admet-698	3	13	:	:	PUNCT
admet-698	3	14	may	may	AUX
admet-698	3	15	13	13	NUM
admet-698	3	16	,	,	PUNCT
admet-698	3	17	2019	2019	NUM
admet-698	3	18	;	;	PUNCT
admet-698	3	19	revised	revise	VERB
admet-698	3	20	:	:	PUNCT
admet-698	3	21	may	may	AUX
admet-698	3	22	27	27	NUM
admet-698	3	23	,	,	PUNCT
admet-698	3	24	2019	2019	NUM
admet-698	3	25	;	;	PUNCT
admet-698	3	26	published	publish	VERB
admet-698	3	27	online	online	ADV
admet-698	3	28	:	:	PUNCT
admet-698	3	29	june	june	PROPN
admet-698	3	30	05	05	NUM
admet-698	3	31	,	,	PUNCT
admet-698	3	32	2019	2019	NUM
admet-698	3	33	abstract	abstract	ADV
admet-698	3	34	this	this	DET
admet-698	3	35	commentary	commentary	NOUN
admet-698	3	36	compares	compare	VERB
admet-698	3	37	233	233	NUM
admet-698	3	38	cheqsol	cheqsol	NOUN
admet-698	3	39	intrinsic	intrinsic	ADJ
admet-698	3	40	solubility	solubility	NOUN
admet-698	3	41	values	value	NOUN
admet-698	3	42	(	(	PUNCT
admet-698	3	43	log	log	NOUN
admet-698	3	44	s0	s0	PROPN
admet-698	3	45	)	)	PUNCT
admet-698	3	46	reported	report	VERB
admet-698	3	47	in	in	ADP
admet-698	3	48	the	the	DET
admet-698	3	49	wiki	wiki	NOUN
admet-698	3	50	-	-	PUNCT
admet-698	3	51	ps0	ps0	ADJ
admet-698	3	52	database	database	NOUN
admet-698	3	53	for	for	ADP
admet-698	3	54	145	145	NUM
admet-698	3	55	different	different	ADJ
admet-698	3	56	druglike	druglike	NOUN
admet-698	3	57	molecules	molecule	NOUN
admet-698	3	58	to	to	ADP
admet-698	3	59	the	the	DET
admet-698	3	60	838	838	NUM
admet-698	3	61	log	log	NOUN
admet-698	3	62	s0	s0	NOUN
admet-698	3	63	values	value	NOUN
admet-698	3	64	determined	determine	VERB
admet-698	3	65	mostly	mostly	ADV
admet-698	3	66	by	by	ADP
admet-698	3	67	the	the	DET
admet-698	3	68	saturation	saturation	NOUN
admet-698	3	69	shakeflask	shakeflask	NOUN
admet-698	3	70	(	(	PUNCT
admet-698	3	71	ssf	ssf	NOUN
admet-698	3	72	)	)	PUNCT
admet-698	3	73	method	method	NOUN
admet-698	3	74	for	for	ADP
admet-698	3	75	124	124	NUM
admet-698	3	76	of	of	ADP
admet-698	3	77	the	the	DET
admet-698	3	78	molecules	molecule	NOUN
admet-698	3	79	from	from	ADP
admet-698	3	80	the	the	DET
admet-698	3	81	cheqsol	cheqsol	NOUN
admet-698	3	82	set	set	NOUN
admet-698	3	83	.	.	PUNCT
admet-698	4	1	the	the	DET
admet-698	4	2	range	range	NOUN
admet-698	4	3	of	of	ADP
admet-698	4	4	log	log	NOUN
admet-698	4	5	s0	s0	PROPN
admet-698	4	6	spans	span	NOUN
admet-698	4	7	from	from	ADP
admet-698	4	8	-1.0	-1.0	PROPN
admet-698	4	9	to	to	ADP
admet-698	4	10	-10.6	-10.6	PROPN
admet-698	4	11	(	(	PUNCT
admet-698	4	12	log	log	VERB
admet-698	4	13	molar	molar	ADJ
admet-698	4	14	units	unit	NOUN
admet-698	4	15	)	)	PUNCT
admet-698	4	16	,	,	PUNCT
admet-698	4	17	averaging	average	VERB
admet-698	4	18	at	at	ADP
admet-698	4	19	-3.8	-3.8	PROPN
admet-698	4	20	.	.	PUNCT
admet-698	5	1	the	the	DET
admet-698	5	2	correlation	correlation	NOUN
admet-698	5	3	plot	plot	NOUN
admet-698	5	4	between	between	ADP
admet-698	5	5	the	the	DET
admet-698	5	6	two	two	NUM
admet-698	5	7	methods	method	NOUN
admet-698	5	8	indicates	indicate	VERB
admet-698	5	9	r	r	NOUN
admet-698	5	10	2	2	NUM
admet-698	5	11	=	=	SYM
admet-698	5	12	0.96	0.96	NUM
admet-698	5	13	,	,	PUNCT
admet-698	5	14	rmse	rmse	NOUN
admet-698	5	15	=	=	SYM
admet-698	5	16	0.34	0.34	NUM
admet-698	5	17	log	log	NOUN
admet-698	5	18	unit	unit	NOUN
admet-698	5	19	,	,	PUNCT
admet-698	5	20	and	and	CCONJ
admet-698	5	21	a	a	DET
admet-698	5	22	slight	slight	ADJ
admet-698	5	23	bias	bias	NOUN
admet-698	5	24	of	of	ADP
admet-698	5	25	-0.07	-0.07	NUM
admet-698	5	26	log	log	PROPN
admet-698	5	27	unit	unit	NOUN
admet-698	5	28	.	.	PUNCT
admet-698	6	1	the	the	DET
admet-698	6	2	average	average	ADJ
admet-698	6	3	interlaboratory	interlaboratory	ADJ
admet-698	6	4	standard	standard	ADJ
admet-698	6	5	deviation	deviation	NOUN
admet-698	6	6	(	(	PUNCT
admet-698	6	7	sdi	sdi	PROPN
admet-698	6	8	)	)	PUNCT
admet-698	6	9	is	be	AUX
admet-698	6	10	slightly	slightly	ADV
admet-698	6	11	better	well	ADJ
admet-698	6	12	for	for	ADP
admet-698	6	13	the	the	DET
admet-698	6	14	cheqsol	cheqsol	NOUN
admet-698	6	15	set	set	NOUN
admet-698	6	16	than	than	ADP
admet-698	6	17	that	that	PRON
admet-698	6	18	of	of	ADP
admet-698	6	19	the	the	DET
admet-698	6	20	ssf	ssf	NOUN
admet-698	6	21	set	set	VERB
admet-698	6	22	:	:	PUNCT
admet-698	6	23	sdi	sdi	PROPN
admet-698	6	24	cs	cs	X
admet-698	6	25	=	=	PUNCT
admet-698	6	26	0.15	0.15	NUM
admet-698	6	27	and	and	CCONJ
admet-698	6	28	sdi	sdi	PROPN
admet-698	6	29	ssf	ssf	NOUN
admet-698	6	30	=	=	PROPN
admet-698	6	31	0.24	0.24	NUM
admet-698	6	32	.	.	PUNCT
admet-698	7	1	the	the	DET
admet-698	7	2	intralaboratory	intralaboratory	ADJ
admet-698	7	3	errors	error	NOUN
admet-698	7	4	reported	report	VERB
admet-698	7	5	in	in	ADP
admet-698	7	6	the	the	DET
admet-698	7	7	cheqsol	cheqsol	ADJ
admet-698	7	8	method	method	NOUN
admet-698	7	9	(	(	PUNCT
admet-698	7	10	0.05	0.05	NUM
admet-698	7	11	log	log	NOUN
admet-698	7	12	)	)	PUNCT
admet-698	7	13	need	need	VERB
admet-698	7	14	to	to	PART
admet-698	7	15	be	be	AUX
admet-698	7	16	multiplied	multiply	VERB
admet-698	7	17	by	by	ADP
admet-698	7	18	a	a	DET
admet-698	7	19	factor	factor	NOUN
admet-698	7	20	of	of	ADP
admet-698	7	21	3	3	NUM
admet-698	7	22	to	to	PART
admet-698	7	23	match	match	VERB
admet-698	7	24	the	the	DET
admet-698	7	25	expected	expect	VERB
admet-698	7	26	interlaboratory	interlaboratory	ADJ
admet-698	7	27	errors	error	NOUN
admet-698	7	28	for	for	ADP
admet-698	7	29	the	the	DET
admet-698	7	30	method	method	NOUN
admet-698	7	31	.	.	PUNCT
admet-698	8	1	the	the	DET
admet-698	8	2	scale	scale	NOUN
admet-698	8	3	factor	factor	NOUN
admet-698	8	4	,	,	PUNCT
admet-698	8	5	in	in	ADP
admet-698	8	6	part	part	NOUN
admet-698	8	7	,	,	PUNCT
admet-698	8	8	relates	relate	VERB
admet-698	8	9	to	to	ADP
admet-698	8	10	the	the	DET
admet-698	8	11	hidden	hide	VERB
admet-698	8	12	systematic	systematic	ADJ
admet-698	8	13	errors	error	NOUN
admet-698	8	14	in	in	ADP
admet-698	8	15	the	the	DET
admet-698	8	16	single	single	ADJ
admet-698	8	17	-	-	PUNCT
admet-698	8	18	lab	lab	NOUN
admet-698	8	19	values	value	NOUN
admet-698	8	20	.	.	PUNCT
admet-698	9	1	it	it	PRON
admet-698	9	2	is	be	AUX
admet-698	9	3	expected	expect	VERB
admet-698	9	4	that	that	SCONJ
admet-698	9	5	improved	improved	ADJ
admet-698	9	6	standardizations	standardization	NOUN
admet-698	9	7	in	in	ADP
admet-698	9	8	the	the	DET
admet-698	9	9	‘	'	PUNCT
admet-698	9	10	gold	gold	ADJ
admet-698	9	11	standard	standard	NOUN
admet-698	9	12	’	'	PUNCT
admet-698	9	13	ssf	ssf	NOUN
admet-698	9	14	method	method	NOUN
admet-698	9	15	,	,	PUNCT
admet-698	9	16	as	as	SCONJ
admet-698	9	17	suggested	suggest	VERB
admet-698	9	18	in	in	ADP
admet-698	9	19	the	the	DET
admet-698	9	20	recent	recent	ADJ
admet-698	9	21	‘	'	PUNCT
admet-698	9	22	white	white	ADJ
admet-698	9	23	paper	paper	NOUN
admet-698	9	24	’	'	PUNCT
admet-698	9	25	on	on	ADP
admet-698	9	26	solubility	solubility	NOUN
admet-698	9	27	measurement	measurement	NOUN
admet-698	9	28	methodology	methodology	NOUN
admet-698	9	29	,	,	PUNCT
admet-698	9	30	should	should	AUX
admet-698	9	31	make	make	VERB
admet-698	9	32	the	the	DET
admet-698	9	33	sdi	sdi	NOUN
admet-698	9	34	of	of	ADP
admet-698	9	35	both	both	DET
admet-698	9	36	methods	method	NOUN
admet-698	9	37	be	be	VERB
admet-698	9	38	about	about	ADP
admet-698	9	39	~0.15	~0.15	PUNCT
admet-698	9	40	log	log	NOUN
admet-698	9	41	unit	unit	NOUN
admet-698	9	42	.	.	PUNCT
admet-698	10	1	the	the	PRON
admet-698	10	2	multi	multi	ADJ
admet-698	10	3	-	-	ADJ
admet-698	10	4	lab	lab	NOUN
admet-698	10	5	averaged	average	VERB
admet-698	10	6	log	log	NOUN
admet-698	10	7	s0	s0	PROPN
admet-698	10	8	(	(	PUNCT
admet-698	10	9	and	and	CCONJ
admet-698	10	10	the	the	DET
admet-698	10	11	corresponding	corresponding	ADJ
admet-698	10	12	sdi	sdi	PROPN
admet-698	10	13	)	)	PUNCT
admet-698	10	14	values	value	NOUN
admet-698	10	15	could	could	AUX
admet-698	10	16	be	be	AUX
admet-698	10	17	helpful	helpful	ADJ
admet-698	10	18	additions	addition	NOUN
admet-698	10	19	to	to	ADP
admet-698	10	20	existing	exist	VERB
admet-698	10	21	training	training	NOUN
admet-698	10	22	-	-	PUNCT
admet-698	10	23	set	set	VERB
admet-698	10	24	molecules	molecule	NOUN
admet-698	10	25	used	use	VERB
admet-698	10	26	to	to	PART
admet-698	10	27	predict	predict	VERB
admet-698	10	28	the	the	DET
admet-698	10	29	intrinsic	intrinsic	ADJ
admet-698	10	30	solubility	solubility	NOUN
admet-698	10	31	of	of	ADP
admet-698	10	32	drugs	drug	NOUN
admet-698	10	33	and	and	CCONJ
admet-698	10	34	druglike	druglike	ADJ
admet-698	10	35	molecules	molecule	NOUN
admet-698	10	36	.	.	PUNCT
admet-698	11	1	keywords	keyword	VERB
admet-698	11	2	interlaboratory	interlaboratory	ADJ
admet-698	11	3	solubility	solubility	NOUN
admet-698	11	4	measurement	measurement	NOUN
admet-698	11	5	errors	error	NOUN
admet-698	11	6	;	;	PUNCT
admet-698	11	7	aqueous	aqueous	ADJ
admet-698	11	8	intrinsic	intrinsic	ADJ
admet-698	11	9	solubility	solubility	NOUN
admet-698	11	10	;	;	PUNCT
admet-698	11	11	shake	shake	NOUN
admet-698	11	12	-	-	PUNCT
admet-698	11	13	flask	flask	NOUN
admet-698	11	14	solubility	solubility	NOUN
admet-698	11	15	;	;	PUNCT
admet-698	11	16	potentio	potentio	PROPN
admet-698	11	17	metric	metric	PROPN
admet-698	11	18	solubility	solubility	PROPN
admet-698	11	19	;	;	PUNCT
admet-698	11	20	thermodynamic	thermodynamic	ADJ
admet-698	11	21	solubility	solubility	NOUN
admet-698	11	22	;	;	PUNCT
admet-698	11	23	henderson	henderson	PROPN
admet-698	11	24	-	-	PUNCT
admet-698	11	25	hasselbalch	hasselbalch	PROPN
admet-698	11	26	equation	equation	NOUN
admet-698	11	27	introduction	introduction	NOUN
admet-698	11	28	this	this	DET
admet-698	11	29	commentary	commentary	NOUN
admet-698	11	30	considers	consider	VERB
admet-698	11	31	the	the	DET
admet-698	11	32	interlaboratory	interlaboratory	ADJ
admet-698	11	33	reproducibility	reproducibility	NOUN
admet-698	11	34	of	of	ADP
admet-698	11	35	published	publish	VERB
admet-698	11	36	aqueous	aqueous	ADJ
admet-698	11	37	intrinsic	intrinsic	ADJ
admet-698	11	38	solubility	solubility	NOUN
admet-698	11	39	data	datum	NOUN
admet-698	11	40	(	(	PUNCT
admet-698	11	41	log	log	NOUN
admet-698	11	42	s0	s0	PROPN
admet-698	11	43	)	)	PUNCT
admet-698	11	44	for	for	ADP
admet-698	11	45	124	124	NUM
admet-698	11	46	drugs	drug	NOUN
admet-698	11	47	,	,	PUNCT
admet-698	11	48	determined	determine	VERB
admet-698	11	49	both	both	PRON
admet-698	11	50	by	by	ADP
admet-698	11	51	the	the	DET
admet-698	11	52	potentiometric	potentiometric	ADJ
admet-698	11	53	cheqsol	cheqsol	NOUN
admet-698	11	54	(	(	PUNCT
admet-698	11	55	cs	cs	ADJ
admet-698	11	56	)	)	PUNCT
admet-698	11	57	method	method	NOUN
admet-698	11	58	(	(	PUNCT
admet-698	11	59	233	233	NUM
admet-698	11	60	reported	report	VERB
admet-698	11	61	log	log	NOUN
admet-698	11	62	s0	s0	PROPN
admet-698	11	63	cs	cs	PROPN
admet-698	11	64	values	value	NOUN
admet-698	11	65	)	)	PUNCT
admet-698	11	66	and	and	CCONJ
admet-698	11	67	mostly	mostly	ADV
admet-698	11	68	by	by	ADP
admet-698	11	69	the	the	DET
admet-698	11	70	‘	'	PUNCT
admet-698	11	71	gold	gold	ADJ
admet-698	11	72	standard	standard	NOUN
admet-698	11	73	’	'	PUNCT
admet-698	11	74	saturation	saturation	NOUN
admet-698	11	75	shake	shake	NOUN
admet-698	11	76	-	-	PUNCT
admet-698	11	77	flask	flask	NOUN
admet-698	11	78	(	(	PUNCT
admet-698	11	79	ssf	ssf	NOUN
admet-698	11	80	)	)	PUNCT
admet-698	11	81	method	method	NOUN
admet-698	11	82	(	(	PUNCT
admet-698	11	83	838	838	NUM
admet-698	11	84	log	log	NOUN
admet-698	11	85	s0	s0	PROPN
admet-698	11	86	ssf	ssf	PROPN
admet-698	11	87	)	)	PUNCT
admet-698	11	88	.	.	PUNCT
admet-698	12	1	for	for	ADP
admet-698	12	2	each	each	DET
admet-698	12	3	drug	drug	NOUN
admet-698	12	4	,	,	PUNCT
admet-698	12	5	its	its	PRON
admet-698	12	6	method	method	NOUN
admet-698	12	7	-	-	PUNCT
admet-698	12	8	dependent	dependent	ADJ
admet-698	12	9	interlaboratory	interlaboratory	ADJ
admet-698	12	10	measurement	measurement	NOUN
admet-698	12	11	standard	standard	ADJ
admet-698	12	12	deviations	deviation	NOUN
admet-698	12	13	(	(	PUNCT
admet-698	12	14	sdi	sdi	X
admet-698	12	15	cs	cs	PROPN
admet-698	12	16	and	and	CCONJ
admet-698	12	17	sdi	sdi	PROPN
admet-698	12	18	ssf	ssf	PROPN
admet-698	12	19	)	)	PUNCT
admet-698	12	20	are	be	AUX
admet-698	12	21	estimated	estimate	VERB
admet-698	12	22	,	,	PUNCT
admet-698	12	23	by	by	ADP
admet-698	12	24	comparing	compare	VERB
admet-698	12	25	solubility	solubility	NOUN
admet-698	12	26	values	value	NOUN
admet-698	12	27	for	for	ADP
admet-698	12	28	a	a	DET
admet-698	12	29	given	give	VERB
admet-698	12	30	drug	drug	NOUN
admet-698	12	31	determined	determine	VERB
admet-698	12	32	in	in	ADP
admet-698	12	33	different	different	ADJ
admet-698	12	34	laboratories	laboratory	NOUN
admet-698	12	35	.	.	PUNCT
admet-698	13	1	the	the	DET
admet-698	13	2	multilab	multilab	NOUN
admet-698	13	3	averaged	average	VERB
admet-698	13	4	log	log	NOUN
admet-698	13	5	s0	s0	PROPN
admet-698	13	6	(	(	PUNCT
admet-698	13	7	and	and	CCONJ
admet-698	13	8	the	the	DET
admet-698	13	9	corresponding	corresponding	ADJ
admet-698	13	10	sdi	sdi	PROPN
admet-698	13	11	values	value	NOUN
admet-698	13	12	)	)	PUNCT
admet-698	13	13	could	could	AUX
admet-698	13	14	be	be	AUX
admet-698	13	15	helpful	helpful	ADJ
admet-698	13	16	additions	addition	NOUN
admet-698	13	17	to	to	ADP
admet-698	13	18	existing	exist	VERB
admet-698	13	19	training	training	NOUN
admet-698	13	20	-	-	PUNCT
admet-698	13	21	set	set	VERB
admet-698	13	22	molecules	molecule	NOUN
admet-698	13	23	used	use	VERB
admet-698	13	24	to	to	PART
admet-698	13	25	predict	predict	VERB
admet-698	13	26	the	the	DET
admet-698	13	27	intrinsic	intrinsic	ADJ
admet-698	13	28	solubility	solubility	NOUN
admet-698	13	29	of	of	ADP
admet-698	13	30	drugs	drug	NOUN
admet-698	13	31	and	and	CCONJ
admet-698	13	32	druglike	druglike	ADJ
admet-698	13	33	molecules	molecule	NOUN
admet-698	13	34	.	.	PUNCT
admet-698	14	1	the	the	DET
admet-698	14	2	present	present	ADJ
admet-698	14	3	contribution	contribution	NOUN
admet-698	14	4	is	be	AUX
admet-698	14	5	the	the	DET
admet-698	14	6	third	third	ADJ
admet-698	14	7	in	in	ADP
admet-698	14	8	a	a	DET
admet-698	14	9	series	series	NOUN
admet-698	14	10	of	of	ADP
admet-698	14	11	papers	paper	NOUN
admet-698	14	12	aiming	aim	VERB
admet-698	14	13	to	to	PART
admet-698	14	14	address	address	VERB
admet-698	14	15	contemporary	contemporary	ADJ
admet-698	14	16	issues	issue	NOUN
admet-698	14	17	of	of	ADP
admet-698	14	18	solubility	solubility	NOUN
admet-698	14	19	measurement	measurement	NOUN
admet-698	14	20	,	,	PUNCT
admet-698	14	21	interpretation	interpretation	NOUN
admet-698	14	22	and	and	CCONJ
admet-698	14	23	prediction	prediction	NOUN
admet-698	14	24	[	[	X
admet-698	14	25	1,2	1,2	NUM
admet-698	14	26	]	]	PUNCT
admet-698	14	27	.	.	PUNCT
admet-698	15	1	these	these	PRON
admet-698	15	2	are	be	AUX
admet-698	15	3	intended	intend	VERB
admet-698	15	4	to	to	PART
admet-698	15	5	serve	serve	VERB
admet-698	15	6	as	as	ADP
admet-698	15	7	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-698	15	8	mailto:alex@in-adme.com	mailto:alex@in-adme.com	PROPN
admet-698	15	9	admet	admet	PROPN
admet-698	15	10	&	&	CCONJ
admet-698	15	11	dmpk	dmpk	PROPN
admet-698	15	12	7(3	7(3	NUM
admet-698	15	13	)	)	PUNCT
admet-698	15	14	(	(	PUNCT
admet-698	15	15	2019	2019	NUM
admet-698	15	16	)	)	PUNCT
admet-698	15	17	210	210	NUM
admet-698	15	18	-	-	SYM
admet-698	15	19	219	219	NUM
admet-698	15	20	multi	multi	ADJ
admet-698	15	21	-	-	ADJ
admet-698	15	22	lab	lab	ADJ
admet-698	15	23	log	log	NOUN
admet-698	15	24	s0	s0	PROPN
admet-698	15	25	measurement	measurement	PROPN
admet-698	15	26	reproducibility	reproducibility	NOUN
admet-698	15	27	in	in	ADP
admet-698	15	28	cheqsol	cheqsol	NOUN
admet-698	15	29	and	and	CCONJ
admet-698	15	30	shake	shake	NOUN
admet-698	15	31	-	-	PUNCT
admet-698	15	32	flask	flask	NOUN
admet-698	15	33	methods	method	NOUN
admet-698	15	34	doi	doi	NOUN
admet-698	15	35	:	:	PUNCT
admet-698	15	36	10.5599	10.5599	NUM
admet-698	15	37	/	/	SYM
admet-698	15	38	admet.698	admet.698	ADJ
admet-698	15	39	211	211	NUM
admet-698	15	40	prologue	prologue	NOUN
admet-698	15	41	/	/	SYM
admet-698	15	42	accompaniment	accompaniment	NOUN
admet-698	15	43	to	to	ADP
admet-698	15	44	an	an	DET
admet-698	15	45	upcoming	upcoming	ADJ
admet-698	15	46	session	session	NOUN
admet-698	15	47	on	on	ADP
admet-698	15	48	solubility	solubility	NOUN
admet-698	15	49	at	at	ADP
admet-698	15	50	the	the	DET
admet-698	15	51	iapc-8	iapc-8	NUM
admet-698	15	52	meeting	meeting	NOUN
admet-698	15	53	in	in	ADP
admet-698	15	54	split	split	NOUN
admet-698	15	55	,	,	PUNCT
admet-698	15	56	croatia	croatia	PROPN
admet-698	15	57	,	,	PUNCT
admet-698	15	58	9	9	NUM
admet-698	15	59	-	-	SYM
admet-698	15	60	11	11	NUM
admet-698	15	61	september	september	PROPN
admet-698	15	62	2019	2019	NUM
admet-698	15	63	.	.	PUNCT
admet-698	16	1	since	since	SCONJ
admet-698	16	2	2009	2009	NUM
admet-698	16	3	,	,	PUNCT
admet-698	16	4	the	the	DET
admet-698	16	5	international	international	ADJ
admet-698	16	6	association	association	NOUN
admet-698	16	7	of	of	ADP
admet-698	16	8	physical	physical	ADJ
admet-698	16	9	chemists	chemist	NOUN
admet-698	16	10	(	(	PUNCT
admet-698	16	11	iapc	iapc	PROPN
admet-698	16	12	,	,	PUNCT
admet-698	16	13	www.iapchem.org	www.iapchem.org	PROPN
admet-698	16	14	)	)	PUNCT
admet-698	16	15	series	series	NOUN
admet-698	16	16	of	of	ADP
admet-698	16	17	symposia	symposia	NOUN
admet-698	16	18	maintained	maintain	VERB
admet-698	16	19	extensive	extensive	ADJ
admet-698	16	20	coverage	coverage	NOUN
admet-698	16	21	of	of	ADP
admet-698	16	22	the	the	DET
admet-698	16	23	topic	topic	NOUN
admet-698	16	24	of	of	ADP
admet-698	16	25	solubility	solubility	NOUN
admet-698	16	26	measurement	measurement	NOUN
admet-698	16	27	,	,	PUNCT
admet-698	16	28	both	both	CCONJ
admet-698	16	29	from	from	ADP
admet-698	16	30	solid	solid	ADJ
admet-698	16	31	state	state	NOUN
admet-698	16	32	and	and	CCONJ
admet-698	16	33	solution	solution	NOUN
admet-698	16	34	perspectives	perspective	NOUN
admet-698	16	35	.	.	PUNCT
admet-698	17	1	at	at	ADP
admet-698	17	2	the	the	DET
admet-698	17	3	2015	2015	NUM
admet-698	17	4	iapc-4	iapc-4	NUM
admet-698	17	5	meeting	meeting	NOUN
admet-698	17	6	,	,	PUNCT
admet-698	17	7	the	the	DET
admet-698	17	8	special	special	ADJ
admet-698	17	9	session	session	NOUN
admet-698	17	10	on	on	ADP
admet-698	17	11	solubility	solubility	NOUN
admet-698	17	12	measurement	measurement	NOUN
admet-698	17	13	resulted	result	VERB
admet-698	17	14	in	in	ADP
admet-698	17	15	a	a	DET
admet-698	17	16	widely	widely	ADV
admet-698	17	17	-	-	PUNCT
admet-698	17	18	circulated	circulate	VERB
admet-698	17	19	‘	'	PUNCT
admet-698	17	20	white	white	ADJ
admet-698	17	21	paper	paper	NOUN
admet-698	17	22	’	'	PUNCT
admet-698	17	23	drawing	draw	VERB
admet-698	17	24	on	on	ADP
admet-698	17	25	expert	expert	ADJ
admet-698	17	26	consensus	consensus	NOUN
admet-698	17	27	thoughts	thought	NOUN
admet-698	17	28	of	of	ADP
admet-698	17	29	scientists	scientist	NOUN
admet-698	17	30	from	from	ADP
admet-698	17	31	six	six	NUM
admet-698	17	32	countries	country	NOUN
admet-698	17	33	(	(	PUNCT
admet-698	17	34	hungary	hungary	PROPN
admet-698	17	35	,	,	PUNCT
admet-698	17	36	russia	russia	PROPN
admet-698	17	37	,	,	PUNCT
admet-698	17	38	serbia	serbia	PROPN
admet-698	17	39	,	,	PUNCT
admet-698	17	40	spain	spain	PROPN
admet-698	17	41	,	,	PUNCT
admet-698	17	42	sweden	sweden	PROPN
admet-698	17	43	,	,	PUNCT
admet-698	17	44	united	united	PROPN
admet-698	17	45	states	states	PROPN
admet-698	17	46	)	)	PUNCT
admet-698	18	1	[	[	X
admet-698	18	2	3	3	NUM
admet-698	18	3	]	]	PUNCT
admet-698	18	4	.	.	PUNCT
admet-698	19	1	it	it	PRON
admet-698	19	2	is	be	AUX
admet-698	19	3	expected	expect	VERB
admet-698	19	4	that	that	SCONJ
admet-698	19	5	future	future	ADJ
admet-698	19	6	sessions	session	NOUN
admet-698	19	7	will	will	AUX
admet-698	19	8	continue	continue	VERB
admet-698	19	9	to	to	PART
admet-698	19	10	cover	cover	VERB
admet-698	19	11	solubility	solubility	NOUN
admet-698	19	12	methods	method	NOUN
admet-698	19	13	and	and	CCONJ
admet-698	19	14	strategies	strategy	NOUN
admet-698	19	15	,	,	PUNCT
admet-698	19	16	to	to	PART
admet-698	19	17	critically	critically	ADV
admet-698	19	18	address	address	VERB
admet-698	19	19	the	the	DET
admet-698	19	20	different	different	ADJ
admet-698	19	21	needs	need	NOUN
admet-698	19	22	in	in	ADP
admet-698	19	23	pharmaceutical	pharmaceutical	ADJ
admet-698	19	24	research	research	NOUN
admet-698	19	25	,	,	PUNCT
admet-698	19	26	spanning	span	VERB
admet-698	19	27	from	from	ADP
admet-698	19	28	drug	drug	NOUN
admet-698	19	29	discovery	discovery	NOUN
admet-698	19	30	to	to	ADP
admet-698	19	31	drug	drug	NOUN
admet-698	19	32	development	development	NOUN
admet-698	19	33	.	.	PUNCT
admet-698	20	1	background	background	NOUN
admet-698	20	2	most	most	ADJ
admet-698	20	3	of	of	ADP
admet-698	20	4	the	the	DET
admet-698	20	5	small	small	ADJ
admet-698	20	6	-	-	PUNCT
admet-698	20	7	molecule	molecule	NOUN
admet-698	20	8	research	research	NOUN
admet-698	20	9	compounds	compound	NOUN
admet-698	20	10	in	in	ADP
admet-698	20	11	today	today	NOUN
admet-698	20	12	’s	’s	PART
admet-698	20	13	drug	drug	NOUN
admet-698	20	14	discovery	discovery	NOUN
admet-698	20	15	projects	project	NOUN
admet-698	20	16	are	be	AUX
admet-698	20	17	ionizable	ionizable	ADJ
admet-698	20	18	and	and	CCONJ
admet-698	20	19	poorly	poorly	ADV
admet-698	20	20	soluble	soluble	ADJ
admet-698	20	21	in	in	ADP
admet-698	20	22	water	water	NOUN
admet-698	20	23	,	,	PUNCT
admet-698	20	24	and	and	CCONJ
admet-698	20	25	are	be	AUX
admet-698	20	26	thus	thus	ADV
admet-698	20	27	prone	prone	ADJ
admet-698	20	28	to	to	PART
admet-698	20	29	show	show	VERB
admet-698	20	30	low	low	ADJ
admet-698	20	31	and/or	and/or	CCONJ
admet-698	20	32	erratic	erratic	ADJ
admet-698	20	33	in	in	ADP
admet-698	20	34	vivo	vivo	ADJ
admet-698	20	35	intestinal	intestinal	ADJ
admet-698	20	36	absorption	absorption	NOUN
admet-698	20	37	[	[	X
admet-698	20	38	4	4	NUM
admet-698	20	39	]	]	PUNCT
admet-698	20	40	.	.	PUNCT
admet-698	21	1	in	in	ADP
admet-698	21	2	discovery	discovery	PROPN
admet-698	21	3	,	,	PUNCT
admet-698	21	4	high	high	ADJ
admet-698	21	5	-	-	PUNCT
admet-698	21	6	throughput	throughput	NOUN
admet-698	21	7	microtitre	microtitre	NOUN
admet-698	21	8	plate	plate	NOUN
admet-698	21	9	methods	method	NOUN
admet-698	21	10	are	be	AUX
admet-698	21	11	used	use	VERB
admet-698	21	12	to	to	PART
admet-698	21	13	estimate	estimate	VERB
admet-698	21	14	solubility	solubility	NOUN
admet-698	21	15	,	,	PUNCT
admet-698	21	16	where	where	SCONJ
admet-698	21	17	small	small	ADJ
admet-698	21	18	volumes	volume	NOUN
admet-698	21	19	of	of	ADP
admet-698	21	20	10	10	NUM
admet-698	21	21	mm	mm	PROPN
admet-698	21	22	dmso	dmso	ADJ
admet-698	21	23	solutions	solution	NOUN
admet-698	21	24	of	of	ADP
admet-698	21	25	library	library	NOUN
admet-698	21	26	compounds	compound	NOUN
admet-698	21	27	are	be	AUX
admet-698	21	28	added	add	VERB
admet-698	21	29	to	to	PART
admet-698	21	30	buffer	buffer	VERB
admet-698	21	31	solutions	solution	NOUN
admet-698	21	32	to	to	PART
admet-698	21	33	induce	induce	VERB
admet-698	21	34	formation	formation	NOUN
admet-698	21	35	of	of	ADP
admet-698	21	36	solid	solid	ADJ
admet-698	21	37	suspensions	suspension	NOUN
admet-698	21	38	in	in	ADP
admet-698	21	39	the	the	DET
admet-698	21	40	wells	well	NOUN
admet-698	21	41	.	.	PUNCT
admet-698	22	1	such	such	ADJ
admet-698	22	2	estimates	estimate	NOUN
admet-698	22	3	of	of	ADP
admet-698	22	4	solubility	solubility	NOUN
admet-698	22	5	are	be	AUX
admet-698	22	6	needed	need	VERB
admet-698	22	7	,	,	PUNCT
admet-698	22	8	in	in	ADP
admet-698	22	9	part	part	NOUN
admet-698	22	10	,	,	PUNCT
admet-698	22	11	to	to	PART
admet-698	22	12	anticipate	anticipate	VERB
admet-698	22	13	whether	whether	SCONJ
admet-698	22	14	compounds	compound	NOUN
admet-698	22	15	would	would	AUX
admet-698	22	16	precipitate	precipitate	VERB
admet-698	22	17	in	in	ADP
admet-698	22	18	bioassays	bioassay	NOUN
admet-698	22	19	(	(	PUNCT
admet-698	22	20	and	and	CCONJ
admet-698	22	21	thus	thus	ADV
admet-698	22	22	indicate	indicate	VERB
admet-698	22	23	false	false	ADJ
admet-698	22	24	positives	positive	NOUN
admet-698	22	25	)	)	PUNCT
admet-698	22	26	.	.	PUNCT
admet-698	23	1	in	in	ADP
admet-698	23	2	parallel	parallel	NOUN
admet-698	23	3	,	,	PUNCT
admet-698	23	4	methods	method	NOUN
admet-698	23	5	to	to	PART
admet-698	23	6	predict	predict	VERB
admet-698	23	7	solubility	solubility	NOUN
admet-698	23	8	of	of	ADP
admet-698	23	9	molecules	molecule	NOUN
admet-698	23	10	play	play	VERB
admet-698	23	11	an	an	DET
admet-698	23	12	important	important	ADJ
admet-698	23	13	role	role	NOUN
admet-698	23	14	in	in	ADP
admet-698	23	15	drug	drug	NOUN
admet-698	23	16	discovery	discovery	NOUN
admet-698	23	17	,	,	PUNCT
admet-698	23	18	since	since	SCONJ
admet-698	23	19	virtual	virtual	ADJ
admet-698	23	20	screening	screening	NOUN
admet-698	23	21	of	of	ADP
admet-698	23	22	compound	compound	NOUN
admet-698	23	23	libraries	library	NOUN
admet-698	23	24	could	could	AUX
admet-698	23	25	prioritize	prioritize	VERB
admet-698	23	26	molecules	molecule	NOUN
admet-698	23	27	for	for	ADP
admet-698	23	28	testing	testing	NOUN
admet-698	23	29	in	in	ADP
admet-698	23	30	early	early	ADV
admet-698	23	31	in	in	ADV
admet-698	23	32	vitro	vitro	X
admet-698	23	33	screens	screen	NOUN
admet-698	24	1	[	[	X
admet-698	24	2	2,5,6	2,5,6	NUM
admet-698	24	3	]	]	X
admet-698	24	4	.	.	PUNCT
admet-698	25	1	saturation	saturation	NOUN
admet-698	25	2	shake	shake	NOUN
admet-698	25	3	-	-	PUNCT
admet-698	25	4	flask	flask	NOUN
admet-698	25	5	(	(	PUNCT
admet-698	25	6	ssf	ssf	NOUN
admet-698	25	7	)	)	PUNCT
admet-698	25	8	and	and	CCONJ
admet-698	25	9	potentiometric	potentiometric	ADJ
admet-698	25	10	(	(	PUNCT
admet-698	25	11	cheqsol	cheqsol	ADJ
admet-698	25	12	)	)	PUNCT
admet-698	25	13	methods	method	NOUN
admet-698	25	14	in	in	ADP
admet-698	25	15	more	more	ADV
admet-698	25	16	advanced	advanced	ADJ
admet-698	25	17	stages	stage	NOUN
admet-698	25	18	of	of	ADP
admet-698	25	19	drug	drug	NOUN
admet-698	25	20	research	research	NOUN
admet-698	25	21	,	,	PUNCT
admet-698	25	22	solubility	solubility	NOUN
admet-698	25	23	measurement	measurement	NOUN
admet-698	25	24	necessarily	necessarily	ADV
admet-698	25	25	becomes	become	VERB
admet-698	25	26	more	more	ADV
admet-698	25	27	rigorous	rigorous	ADJ
admet-698	25	28	,	,	PUNCT
admet-698	25	29	where	where	SCONJ
admet-698	25	30	‘	'	PUNCT
admet-698	25	31	solubility	solubility	NOUN
admet-698	25	32	’	'	PUNCT
admet-698	25	33	refers	refer	VERB
admet-698	25	34	to	to	ADP
admet-698	25	35	the	the	DET
admet-698	25	36	concentration	concentration	NOUN
admet-698	25	37	of	of	ADP
admet-698	25	38	a	a	DET
admet-698	25	39	solute	solute	NOUN
admet-698	25	40	in	in	ADP
admet-698	25	41	a	a	DET
admet-698	25	42	saturated	saturated	ADJ
admet-698	25	43	solution	solution	NOUN
admet-698	25	44	,	,	PUNCT
admet-698	25	45	where	where	SCONJ
admet-698	25	46	the	the	DET
admet-698	25	47	dissolved	dissolve	VERB
admet-698	25	48	molecule	molecule	NOUN
admet-698	25	49	is	be	AUX
admet-698	25	50	in	in	ADP
admet-698	25	51	a	a	DET
admet-698	25	52	thermodynamic	thermodynamic	ADJ
admet-698	25	53	equilibrium	equilibrium	NOUN
admet-698	25	54	with	with	ADP
admet-698	25	55	its	its	PRON
admet-698	25	56	crystalline	crystalline	ADJ
admet-698	25	57	form	form	NOUN
admet-698	25	58	suspended	suspend	VERB
admet-698	25	59	in	in	ADP
admet-698	25	60	the	the	DET
admet-698	25	61	solution	solution	NOUN
admet-698	25	62	(	(	PUNCT
admet-698	25	63	of	of	ADP
admet-698	25	64	a	a	DET
admet-698	25	65	known	know	VERB
admet-698	25	66	ph	ph	NOUN
admet-698	25	67	,	,	PUNCT
admet-698	25	68	composition	composition	NOUN
admet-698	25	69	,	,	PUNCT
admet-698	25	70	and	and	CCONJ
admet-698	25	71	temperature	temperature	NOUN
admet-698	25	72	)	)	PUNCT
admet-698	25	73	.	.	PUNCT
admet-698	26	1	accurate	accurate	ADJ
admet-698	26	2	solubility	solubility	NOUN
admet-698	26	3	measurement	measurement	NOUN
admet-698	26	4	of	of	ADP
admet-698	26	5	druglike	druglike	ADJ
admet-698	26	6	molecules	molecule	NOUN
admet-698	26	7	can	can	AUX
admet-698	26	8	be	be	AUX
admet-698	26	9	very	very	ADV
admet-698	26	10	difficult	difficult	ADJ
admet-698	26	11	to	to	PART
admet-698	26	12	do	do	VERB
admet-698	26	13	well	well	ADV
admet-698	26	14	,	,	PUNCT
admet-698	26	15	although	although	SCONJ
admet-698	26	16	to	to	ADP
admet-698	26	17	an	an	DET
admet-698	26	18	untrained	untrained	ADJ
admet-698	26	19	eye	eye	NOUN
admet-698	26	20	it	it	PRON
admet-698	26	21	ought	ought	AUX
admet-698	26	22	to	to	PART
admet-698	26	23	be	be	AUX
admet-698	26	24	as	as	ADV
admet-698	26	25	easy	easy	ADJ
admet-698	26	26	as	as	ADP
admet-698	26	27	measuring	measure	VERB
admet-698	26	28	the	the	DET
admet-698	26	29	concentration	concentration	NOUN
admet-698	26	30	of	of	ADP
admet-698	26	31	a	a	DET
admet-698	26	32	molecule	molecule	NOUN
admet-698	26	33	in	in	ADP
admet-698	26	34	water	water	NOUN
admet-698	26	35	.	.	PUNCT
admet-698	27	1	in	in	ADP
admet-698	27	2	development	development	NOUN
admet-698	27	3	projects	project	NOUN
admet-698	27	4	,	,	PUNCT
admet-698	27	5	thermodynamic	thermodynamic	ADJ
admet-698	27	6	solubility	solubility	NOUN
admet-698	27	7	measurements	measurement	NOUN
admet-698	27	8	are	be	AUX
admet-698	27	9	usually	usually	ADV
admet-698	27	10	done	do	VERB
admet-698	27	11	using	use	VERB
admet-698	27	12	some	some	DET
admet-698	27	13	variant	variant	NOUN
admet-698	27	14	of	of	ADP
admet-698	27	15	the	the	DET
admet-698	27	16	ssf	ssf	NOUN
admet-698	27	17	method	method	NOUN
admet-698	27	18	[	[	X
admet-698	27	19	3	3	NUM
admet-698	27	20	]	]	PUNCT
admet-698	27	21	.	.	PUNCT
admet-698	28	1	as	as	ADP
admet-698	28	2	an	an	DET
admet-698	28	3	alternative	alternative	NOUN
admet-698	28	4	,	,	PUNCT
admet-698	28	5	a	a	DET
admet-698	28	6	potentiometric	potentiometric	ADJ
admet-698	28	7	procedure	procedure	NOUN
admet-698	28	8	,	,	PUNCT
admet-698	28	9	called	call	VERB
admet-698	28	10	the	the	DET
admet-698	28	11	dissolution	dissolution	NOUN
admet-698	28	12	template	template	NOUN
admet-698	28	13	titration	titration	NOUN
admet-698	28	14	(	(	PUNCT
admet-698	28	15	dtt	dtt	NOUN
admet-698	28	16	)	)	PUNCT
admet-698	28	17	method	method	NOUN
admet-698	28	18	was	be	AUX
admet-698	28	19	introduced	introduce	VERB
admet-698	28	20	in	in	ADP
admet-698	28	21	1998	1998	NUM
admet-698	29	1	[	[	X
admet-698	29	2	7	7	NUM
admet-698	29	3	]	]	PUNCT
admet-698	29	4	and	and	CCONJ
admet-698	29	5	validated	validate	VERB
admet-698	29	6	two	two	NUM
admet-698	29	7	years	year	NOUN
admet-698	29	8	later	later	ADV
admet-698	29	9	[	[	X
admet-698	29	10	8	8	NUM
admet-698	29	11	]	]	PUNCT
admet-698	29	12	.	.	PUNCT
admet-698	30	1	the	the	DET
admet-698	30	2	methodology	methodology	NOUN
admet-698	30	3	is	be	AUX
admet-698	30	4	capable	capable	ADJ
admet-698	30	5	of	of	ADP
admet-698	30	6	producing	produce	VERB
admet-698	30	7	highly	highly	ADV
admet-698	30	8	precise	precise	ADJ
admet-698	30	9	(	(	PUNCT
admet-698	30	10	intralaboratory	intralaboratory	ADJ
admet-698	30	11	sd	sd	ADP
admet-698	30	12	~0.07	~0.07	CCONJ
admet-698	30	13	log	log	PROPN
admet-698	30	14	unit	unit	NOUN
admet-698	30	15	)	)	PUNCT
admet-698	30	16	measurements	measurement	NOUN
admet-698	30	17	of	of	ADP
admet-698	30	18	aqueous	aqueous	ADJ
admet-698	30	19	intrinsic	intrinsic	ADJ
admet-698	30	20	solubility	solubility	NOUN
admet-698	30	21	,	,	PUNCT
admet-698	30	22	log	log	NOUN
admet-698	30	23	s0	s0	PROPN
admet-698	30	24	,	,	PUNCT
admet-698	30	25	i.e.	i.e.	X
admet-698	30	26	,	,	PUNCT
admet-698	30	27	the	the	DET
admet-698	30	28	solubility	solubility	NOUN
admet-698	30	29	of	of	ADP
admet-698	30	30	the	the	DET
admet-698	30	31	uncharged	uncharged	ADJ
admet-698	30	32	form	form	NOUN
admet-698	30	33	of	of	ADP
admet-698	30	34	an	an	DET
admet-698	30	35	ionizable	ionizable	ADJ
admet-698	30	36	molecule	molecule	NOUN
admet-698	30	37	.	.	PUNCT
admet-698	31	1	a	a	DET
admet-698	31	2	much	much	ADV
admet-698	31	3	faster	fast	ADJ
admet-698	31	4	variant	variant	NOUN
admet-698	31	5	of	of	ADP
admet-698	31	6	the	the	DET
admet-698	31	7	ph	ph	ADJ
admet-698	31	8	-	-	PUNCT
admet-698	31	9	titration	titration	NOUN
admet-698	31	10	method	method	NOUN
admet-698	31	11	,	,	PUNCT
admet-698	31	12	called	call	VERB
admet-698	31	13	cheqsol	cheqsol	NOUN
admet-698	31	14	,	,	PUNCT
admet-698	31	15	was	be	AUX
admet-698	31	16	described	describe	VERB
admet-698	31	17	in	in	ADP
admet-698	31	18	2005	2005	NUM
admet-698	31	19	[	[	X
admet-698	31	20	9	9	NUM
admet-698	31	21	]	]	PUNCT
admet-698	31	22	.	.	PUNCT
admet-698	32	1	instruments	instrument	NOUN
admet-698	32	2	implementing	implement	VERB
admet-698	32	3	the	the	DET
admet-698	32	4	potentiometric	potentiometric	ADJ
admet-698	32	5	methods	method	NOUN
admet-698	32	6	have	have	AUX
admet-698	32	7	been	be	AUX
admet-698	32	8	used	use	VERB
admet-698	32	9	in	in	ADP
admet-698	32	10	several	several	ADJ
admet-698	32	11	universities	university	NOUN
admet-698	32	12	and	and	CCONJ
admet-698	32	13	pharmaceutical	pharmaceutical	NOUN
admet-698	32	14	companies	company	NOUN
admet-698	32	15	.	.	PUNCT
admet-698	33	1	all	all	PRON
admet-698	33	2	of	of	ADP
admet-698	33	3	the	the	DET
admet-698	33	4	potentiometric	potentiometric	ADJ
admet-698	33	5	methods	method	NOUN
admet-698	33	6	require	require	VERB
admet-698	33	7	that	that	SCONJ
admet-698	33	8	the	the	DET
admet-698	33	9	molecule	molecule	NOUN
admet-698	33	10	be	be	AUX
admet-698	33	11	ionizable	ionizable	ADJ
admet-698	33	12	and	and	CCONJ
admet-698	33	13	that	that	SCONJ
admet-698	33	14	the	the	DET
admet-698	33	15	accuratelymeasured	accuratelymeasure	VERB
admet-698	33	16	pka	pka	PROPN
admet-698	33	17	be	be	AUX
admet-698	33	18	provided	provide	VERB
admet-698	33	19	.	.	PUNCT
admet-698	34	1	the	the	DET
admet-698	34	2	molecule	molecule	NOUN
admet-698	34	3	can	can	AUX
admet-698	34	4	not	not	PART
admet-698	34	5	be	be	AUX
admet-698	34	6	too	too	ADV
admet-698	34	7	soluble	soluble	ADJ
admet-698	34	8	,	,	PUNCT
admet-698	34	9	since	since	SCONJ
admet-698	34	10	the	the	DET
admet-698	34	11	method	method	NOUN
admet-698	34	12	depends	depend	VERB
admet-698	34	13	on	on	ADP
admet-698	34	14	the	the	DET
admet-698	34	15	ph	ph	ADJ
admet-698	34	16	difference	difference	NOUN
admet-698	34	17	between	between	ADP
admet-698	34	18	a	a	DET
admet-698	34	19	saturated	saturated	ADJ
admet-698	34	20	and	and	CCONJ
admet-698	34	21	an	an	DET
admet-698	34	22	unsaturated	unsaturated	ADJ
admet-698	34	23	solution	solution	NOUN
admet-698	34	24	in	in	ADP
admet-698	34	25	the	the	DET
admet-698	34	26	titration	titration	NOUN
admet-698	34	27	where	where	SCONJ
admet-698	34	28	the	the	DET
admet-698	34	29	molecule	molecule	NOUN
admet-698	34	30	is	be	AUX
admet-698	34	31	half	half	ADV
admet-698	34	32	ionized	ionized	ADJ
admet-698	34	33	.	.	PUNCT
admet-698	35	1	so	so	ADV
admet-698	35	2	,	,	PUNCT
admet-698	35	3	it	it	PRON
admet-698	35	4	is	be	AUX
admet-698	35	5	ideally	ideally	ADV
admet-698	35	6	suited	suit	VERB
admet-698	35	7	for	for	ADP
admet-698	35	8	low	low	ADJ
admet-698	35	9	-	-	PUNCT
admet-698	35	10	soluble	soluble	ADJ
admet-698	35	11	molecules	molecule	NOUN
admet-698	35	12	,	,	PUNCT
admet-698	35	13	since	since	SCONJ
admet-698	35	14	these	these	DET
admet-698	35	15	molecules	molecule	NOUN
admet-698	35	16	display	display	VERB
admet-698	35	17	large	large	ADJ
admet-698	35	18	ph	ph	ADJ
admet-698	35	19	differences	difference	NOUN
admet-698	35	20	.	.	PUNCT
admet-698	36	1	furthermore	furthermore	ADV
admet-698	36	2	,	,	PUNCT
admet-698	36	3	to	to	PART
admet-698	36	4	calculate	calculate	VERB
admet-698	36	5	the	the	DET
admet-698	36	6	cheqsol	cheqsol	ADJ
admet-698	36	7	log	log	NOUN
admet-698	36	8	s0	s0	PROPN
admet-698	36	9	,	,	PUNCT
admet-698	36	10	it	it	PRON
admet-698	36	11	is	be	AUX
admet-698	36	12	assumed	assume	VERB
admet-698	36	13	that	that	SCONJ
admet-698	36	14	solubility	solubility	NOUN
admet-698	36	15	as	as	ADP
admet-698	36	16	a	a	DET
admet-698	36	17	function	function	NOUN
admet-698	36	18	of	of	ADP
admet-698	36	19	ph	ph	NOUN
admet-698	36	20	follows	follow	VERB
admet-698	36	21	the	the	DET
admet-698	36	22	curve	curve	NOUN
admet-698	36	23	predicted	predict	VERB
admet-698	36	24	by	by	ADP
admet-698	36	25	the	the	DET
admet-698	36	26	henderson	henderson	PROPN
admet-698	36	27	-	-	PUNCT
admet-698	36	28	hasselbalch	hasselbalch	PROPN
admet-698	36	29	equation	equation	NOUN
admet-698	36	30	.	.	PUNCT
admet-698	37	1	the	the	DET
admet-698	37	2	molecule	molecule	NOUN
admet-698	37	3	needs	need	VERB
admet-698	37	4	to	to	PART
admet-698	37	5	be	be	AUX
admet-698	37	6	stable	stable	ADJ
admet-698	37	7	to	to	ADP
admet-698	37	8	hydrolysis	hydrolysis	NOUN
admet-698	37	9	when	when	SCONJ
admet-698	37	10	repeatedly	repeatedly	ADV
admet-698	37	11	exposed	expose	VERB
admet-698	37	12	to	to	ADP
admet-698	37	13	ph	ph	ADJ
admet-698	37	14	conditions	condition	NOUN
admet-698	37	15	far	far	ADV
admet-698	37	16	from	from	ADP
admet-698	37	17	neutral	neutral	ADJ
admet-698	37	18	.	.	PUNCT
admet-698	38	1	means	mean	VERB
admet-698	38	2	to	to	PART
admet-698	38	3	recognize	recognize	VERB
admet-698	38	4	hydrolytic	hydrolytic	ADJ
admet-698	38	5	decomposition	decomposition	NOUN
admet-698	38	6	are	be	AUX
admet-698	38	7	important	important	ADJ
admet-698	38	8	to	to	PART
admet-698	38	9	incorporate	incorporate	VERB
admet-698	38	10	into	into	ADP
admet-698	38	11	the	the	DET
admet-698	38	12	measurement	measurement	NOUN
admet-698	38	13	.	.	PUNCT
admet-698	39	1	sometimes	sometimes	ADV
admet-698	39	2	multiple	multiple	ADJ
admet-698	39	3	polymorphs	polymorph	NOUN
admet-698	39	4	may	may	AUX
admet-698	39	5	form	form	VERB
admet-698	39	6	in	in	ADP
admet-698	39	7	the	the	DET
admet-698	39	8	cheqsol	cheqsol	ADJ
admet-698	39	9	method	method	NOUN
admet-698	39	10	,	,	PUNCT
admet-698	39	11	which	which	PRON
admet-698	39	12	requires	require	VERB
admet-698	39	13	solid	solid	ADJ
admet-698	39	14	state	state	NOUN
admet-698	39	15	characterization	characterization	NOUN
admet-698	39	16	to	to	PART
admet-698	39	17	identify	identify	VERB
admet-698	39	18	.	.	PUNCT
admet-698	40	1	in	in	ADP
admet-698	40	2	the	the	DET
admet-698	40	3	traditional	traditional	ADJ
admet-698	40	4	ssf	ssf	NOUN
admet-698	40	5	method	method	NOUN
admet-698	40	6	,	,	PUNCT
admet-698	40	7	most	most	ADJ
admet-698	40	8	of	of	ADP
admet-698	40	9	the	the	DET
admet-698	40	10	time	time	NOUN
admet-698	40	11	,	,	PUNCT
admet-698	40	12	the	the	DET
admet-698	40	13	thermodynamically	thermodynamically	ADV
admet-698	40	14	most	most	ADV
admet-698	40	15	-	-	PUNCT
admet-698	40	16	stable	stable	ADJ
admet-698	40	17	form	form	NOUN
admet-698	40	18	of	of	ADP
admet-698	40	19	the	the	DET
admet-698	40	20	solid	solid	NOUN
admet-698	40	21	is	be	AUX
admet-698	40	22	the	the	DET
admet-698	40	23	one	one	NUM
admet-698	40	24	associated	associate	VERB
admet-698	40	25	with	with	ADP
admet-698	40	26	the	the	DET
admet-698	40	27	measured	measured	ADJ
admet-698	40	28	solubility	solubility	NOUN
admet-698	40	29	[	[	X
admet-698	40	30	3	3	NUM
admet-698	40	31	]	]	PUNCT
admet-698	40	32	.	.	PUNCT
admet-698	41	1	equilibration	equilibration	NOUN
admet-698	41	2	times	time	NOUN
admet-698	41	3	are	be	AUX
admet-698	41	4	selected	select	VERB
admet-698	41	5	to	to	PART
admet-698	41	6	be	be	AUX
admet-698	41	7	long	long	ADJ
admet-698	41	8	(	(	PUNCT
admet-698	41	9	24	24	NUM
admet-698	41	10	-	-	SYM
admet-698	41	11	168	168	NUM
admet-698	41	12	h	h	NOUN
admet-698	41	13	)	)	PUNCT
admet-698	41	14	to	to	PART
admet-698	41	15	ensure	ensure	VERB
admet-698	41	16	this	this	DET
admet-698	41	17	expectation	expectation	NOUN
admet-698	41	18	.	.	PUNCT
admet-698	42	1	http://www.iapchem.org/	http://www.iapchem.org/	PROPN
admet-698	42	2	alex	alex	PROPN
admet-698	42	3	avdeef	avdeef	PROPN
admet-698	42	4	admet	admet	PROPN
admet-698	42	5	&	&	CCONJ
admet-698	42	6	dmpk	dmpk	PROPN
admet-698	42	7	7(3	7(3	NUM
admet-698	42	8	)	)	PUNCT
admet-698	42	9	(	(	PUNCT
admet-698	42	10	2019	2019	NUM
admet-698	42	11	)	)	PUNCT
admet-698	42	12	210	210	NUM
admet-698	42	13	-	-	SYM
admet-698	42	14	219	219	NUM
admet-698	42	15	212	212	NUM
admet-698	42	16	challenging	challenging	ADJ
admet-698	42	17	measurement	measurement	NOUN
admet-698	42	18	what	what	PRON
admet-698	42	19	can	can	AUX
admet-698	42	20	make	make	VERB
admet-698	42	21	solubility	solubility	NOUN
admet-698	42	22	measurement	measurement	NOUN
admet-698	42	23	of	of	ADP
admet-698	42	24	an	an	DET
admet-698	42	25	ionizable	ionizable	ADJ
admet-698	42	26	low	low	ADJ
admet-698	42	27	-	-	PUNCT
admet-698	42	28	soluble	soluble	ADJ
admet-698	42	29	molecule	molecule	NOUN
admet-698	42	30	so	so	ADV
admet-698	42	31	difficult	difficult	ADJ
admet-698	42	32	?	?	PUNCT
admet-698	43	1	there	there	PRON
admet-698	43	2	are	be	VERB
admet-698	43	3	two	two	NUM
admet-698	43	4	sides	side	NOUN
admet-698	43	5	to	to	PART
admet-698	43	6	consider	consider	VERB
admet-698	43	7	for	for	ADP
admet-698	43	8	the	the	DET
admet-698	43	9	reaction	reaction	NOUN
admet-698	43	10	at	at	ADP
admet-698	43	11	equilibrium	equilibrium	NOUN
admet-698	43	12	:	:	PUNCT
admet-698	43	13	(	(	PUNCT
admet-698	43	14	a	a	X
admet-698	43	15	)	)	PUNCT
admet-698	43	16	the	the	DET
admet-698	43	17	solid	solid	ADJ
admet-698	43	18	state	state	NOUN
admet-698	43	19	and	and	CCONJ
admet-698	43	20	(	(	PUNCT
admet-698	43	21	b	b	X
admet-698	43	22	)	)	PUNCT
admet-698	43	23	the	the	DET
admet-698	43	24	solution	solution	NOUN
admet-698	43	25	.	.	PUNCT
admet-698	44	1	temperature	temperature	NOUN
admet-698	44	2	needs	need	VERB
admet-698	44	3	to	to	PART
admet-698	44	4	be	be	AUX
admet-698	44	5	regulated	regulate	VERB
admet-698	44	6	and	and	CCONJ
admet-698	44	7	specified	specify	VERB
admet-698	44	8	.	.	PUNCT
admet-698	45	1	to	to	PART
admet-698	45	2	keep	keep	VERB
admet-698	45	3	the	the	DET
admet-698	45	4	following	follow	VERB
admet-698	45	5	examples	example	NOUN
admet-698	45	6	simple	simple	ADJ
admet-698	45	7	,	,	PUNCT
admet-698	45	8	let	let	VERB
admet-698	45	9	’s	’s	PRON
admet-698	45	10	assume	assume	VERB
admet-698	45	11	that	that	SCONJ
admet-698	45	12	the	the	DET
admet-698	45	13	solvent	solvent	NOUN
admet-698	45	14	is	be	AUX
admet-698	45	15	distilled	distil	VERB
admet-698	45	16	water	water	NOUN
admet-698	45	17	or	or	CCONJ
admet-698	45	18	an	an	DET
admet-698	45	19	aqueous	aqueous	ADJ
admet-698	45	20	buffer	buffer	NOUN
admet-698	45	21	,	,	PUNCT
admet-698	45	22	and	and	CCONJ
admet-698	45	23	that	that	SCONJ
admet-698	45	24	the	the	DET
admet-698	45	25	crystalline	crystalline	ADJ
admet-698	45	26	form	form	NOUN
admet-698	45	27	of	of	ADP
admet-698	45	28	the	the	DET
admet-698	45	29	test	test	NOUN
admet-698	45	30	compound	compound	NOUN
admet-698	45	31	is	be	AUX
admet-698	45	32	a	a	DET
admet-698	45	33	free	free	ADJ
admet-698	45	34	-	-	PUNCT
admet-698	45	35	acid	acid	NOUN
admet-698	45	36	/	/	SYM
admet-698	45	37	base	base	NOUN
admet-698	45	38	or	or	CCONJ
admet-698	45	39	a	a	DET
admet-698	45	40	salt	salt	NOUN
admet-698	45	41	.	.	PUNCT
admet-698	46	1	multiple	multiple	ADJ
admet-698	46	2	circumstances	circumstance	NOUN
admet-698	46	3	may	may	AUX
admet-698	46	4	arise	arise	VERB
admet-698	46	5	,	,	PUNCT
admet-698	46	6	some	some	PRON
admet-698	46	7	making	make	VERB
admet-698	46	8	the	the	DET
admet-698	46	9	interpretation	interpretation	NOUN
admet-698	46	10	of	of	ADP
admet-698	46	11	the	the	DET
admet-698	46	12	measurement	measurement	NOUN
admet-698	46	13	challenging	challenge	VERB
admet-698	46	14	:	:	PUNCT
admet-698	46	15	(	(	PUNCT
admet-698	46	16	i	i	NOUN
admet-698	46	17	)	)	PUNCT
admet-698	46	18	the	the	DET
admet-698	46	19	simplest	simple	ADJ
admet-698	46	20	suspension	suspension	NOUN
admet-698	46	21	is	be	AUX
admet-698	46	22	the	the	DET
admet-698	46	23	one	one	NUM
admet-698	46	24	where	where	SCONJ
admet-698	46	25	no	no	DET
admet-698	46	26	drug	drug	NOUN
admet-698	46	27	ionization	ionization	NOUN
admet-698	46	28	takes	take	VERB
admet-698	46	29	place	place	NOUN
admet-698	46	30	on	on	ADP
admet-698	46	31	equilibration	equilibration	NOUN
admet-698	46	32	.	.	PUNCT
admet-698	47	1	one	one	NUM
admet-698	47	2	needs	need	VERB
admet-698	47	3	to	to	PART
admet-698	47	4	measure	measure	VERB
admet-698	47	5	the	the	DET
admet-698	47	6	concentration	concentration	NOUN
admet-698	47	7	of	of	ADP
admet-698	47	8	the	the	DET
admet-698	47	9	compound	compound	NOUN
admet-698	47	10	in	in	ADP
admet-698	47	11	the	the	DET
admet-698	47	12	saturated	saturate	VERB
admet-698	47	13	solution	solution	NOUN
admet-698	47	14	,	,	PUNCT
admet-698	47	15	and	and	CCONJ
admet-698	47	16	to	to	PART
admet-698	47	17	confirm	confirm	VERB
admet-698	47	18	that	that	SCONJ
admet-698	47	19	the	the	DET
admet-698	47	20	solid	solid	ADJ
admet-698	47	21	state	state	NOUN
admet-698	47	22	form	form	NOUN
admet-698	47	23	is	be	AUX
admet-698	47	24	unchanged	unchanged	ADJ
admet-698	47	25	–	–	PUNCT
admet-698	47	26	simple	simple	ADJ
admet-698	47	27	.	.	PUNCT
admet-698	48	1	(	(	PUNCT
admet-698	48	2	ii	ii	NOUN
admet-698	48	3	)	)	PUNCT
admet-698	48	4	however	however	ADV
admet-698	48	5	,	,	PUNCT
admet-698	48	6	if	if	SCONJ
admet-698	48	7	the	the	DET
admet-698	48	8	solid	solid	ADJ
admet-698	48	9	introduced	introduce	VERB
admet-698	48	10	is	be	AUX
admet-698	48	11	not	not	PART
admet-698	48	12	the	the	DET
admet-698	48	13	thermodynamically	thermodynamically	ADV
admet-698	48	14	most	most	ADV
admet-698	48	15	-	-	PUNCT
admet-698	48	16	stable	stable	ADJ
admet-698	48	17	polymorph	polymorph	NOUN
admet-698	48	18	(	(	PUNCT
admet-698	48	19	or	or	CCONJ
admet-698	48	20	is	be	AUX
admet-698	48	21	amorphous	amorphous	ADJ
admet-698	48	22	)	)	PUNCT
admet-698	48	23	,	,	PUNCT
admet-698	48	24	then	then	ADV
admet-698	48	25	it	it	PRON
admet-698	48	26	is	be	AUX
admet-698	48	27	possible	possible	ADJ
admet-698	48	28	that	that	SCONJ
admet-698	48	29	the	the	DET
admet-698	48	30	measured	measured	ADJ
admet-698	48	31	solubility	solubility	NOUN
admet-698	48	32	would	would	AUX
admet-698	48	33	correspond	correspond	VERB
admet-698	48	34	to	to	ADP
admet-698	48	35	a	a	DET
admet-698	48	36	different	different	ADJ
admet-698	48	37	solid	solid	ADJ
admet-698	48	38	form	form	NOUN
admet-698	48	39	.	.	PUNCT
admet-698	49	1	that	that	PRON
admet-698	49	2	’s	’	VERB
admet-698	49	3	important	important	ADJ
admet-698	49	4	to	to	PART
admet-698	49	5	know	know	VERB
admet-698	49	6	.	.	PUNCT
admet-698	50	1	(	(	PUNCT
admet-698	50	2	iii	iii	X
admet-698	50	3	)	)	PUNCT
admet-698	50	4	complication	complication	NOUN
admet-698	50	5	can	can	AUX
admet-698	50	6	arise	arise	VERB
admet-698	50	7	if	if	SCONJ
admet-698	50	8	a	a	DET
admet-698	50	9	low	low	ADJ
admet-698	50	10	-	-	PUNCT
admet-698	50	11	soluble	soluble	ADJ
admet-698	50	12	weak	weak	ADJ
admet-698	50	13	base	base	NOUN
admet-698	50	14	is	be	AUX
admet-698	50	15	added	add	VERB
admet-698	50	16	to	to	ADP
admet-698	50	17	water	water	NOUN
admet-698	50	18	(	(	PUNCT
admet-698	50	19	usually	usually	ADV
admet-698	50	20	saturated	saturate	VERB
admet-698	50	21	with	with	ADP
admet-698	50	22	co2	co2	NOUN
admet-698	50	23	from	from	ADP
admet-698	50	24	the	the	DET
admet-698	50	25	air	air	NOUN
admet-698	50	26	)	)	PUNCT
admet-698	50	27	.	.	PUNCT
admet-698	51	1	the	the	DET
admet-698	51	2	ph	ph	NOUN
admet-698	51	3	will	will	AUX
admet-698	51	4	change	change	VERB
admet-698	51	5	,	,	PUNCT
admet-698	51	6	depending	depend	VERB
admet-698	51	7	on	on	ADP
admet-698	51	8	the	the	DET
admet-698	51	9	pka	pka	NOUN
admet-698	51	10	of	of	ADP
admet-698	51	11	the	the	DET
admet-698	51	12	molecule	molecule	NOUN
admet-698	51	13	.	.	PUNCT
admet-698	52	1	the	the	DET
admet-698	52	2	ambient	ambient	ADJ
admet-698	52	3	co2	co2	NOUN
admet-698	52	4	may	may	AUX
admet-698	52	5	act	act	VERB
admet-698	52	6	as	as	ADP
admet-698	52	7	a	a	DET
admet-698	52	8	buffer	buffer	NOUN
admet-698	52	9	,	,	PUNCT
admet-698	52	10	so	so	CCONJ
admet-698	52	11	the	the	DET
admet-698	52	12	final	final	ADJ
admet-698	52	13	ph	ph	NOUN
admet-698	52	14	of	of	ADP
admet-698	52	15	the	the	DET
admet-698	52	16	saturated	saturate	VERB
admet-698	52	17	solution	solution	NOUN
admet-698	52	18	needs	need	VERB
admet-698	52	19	to	to	PART
admet-698	52	20	be	be	AUX
admet-698	52	21	carefully	carefully	ADV
admet-698	52	22	measured	measure	VERB
admet-698	52	23	.	.	PUNCT
admet-698	53	1	otherwise	otherwise	ADV
admet-698	53	2	,	,	PUNCT
admet-698	53	3	the	the	DET
admet-698	53	4	calculated	calculate	VERB
admet-698	53	5	log	log	NOUN
admet-698	53	6	s0	s0	NOUN
admet-698	53	7	could	could	AUX
admet-698	53	8	be	be	AUX
admet-698	53	9	quite	quite	ADV
admet-698	53	10	erroneous	erroneous	ADJ
admet-698	53	11	.	.	PUNCT
admet-698	54	1	(	(	PUNCT
admet-698	54	2	iv	iv	X
admet-698	54	3	)	)	PUNCT
admet-698	54	4	if	if	SCONJ
admet-698	54	5	a	a	DET
admet-698	54	6	solid	solid	ADJ
admet-698	54	7	salt	salt	NOUN
admet-698	54	8	of	of	ADP
admet-698	54	9	the	the	DET
admet-698	54	10	compound	compound	NOUN
admet-698	54	11	is	be	AUX
admet-698	54	12	added	add	VERB
admet-698	54	13	to	to	ADP
admet-698	54	14	water	water	NOUN
admet-698	54	15	,	,	PUNCT
admet-698	54	16	a	a	DET
admet-698	54	17	supersaturated	supersaturated	ADJ
admet-698	54	18	solution	solution	NOUN
admet-698	54	19	may	may	AUX
admet-698	54	20	form	form	VERB
admet-698	54	21	.	.	PUNCT
admet-698	55	1	on	on	ADP
admet-698	55	2	equilibration	equilibration	NOUN
admet-698	55	3	,	,	PUNCT
admet-698	55	4	there	there	PRON
admet-698	55	5	could	could	AUX
admet-698	55	6	be	be	AUX
admet-698	55	7	two	two	NUM
admet-698	55	8	precipitates	precipitate	NOUN
admet-698	55	9	in	in	ADP
admet-698	55	10	the	the	DET
admet-698	55	11	suspension	suspension	NOUN
admet-698	55	12	:	:	PUNCT
admet-698	55	13	the	the	DET
admet-698	55	14	original	original	ADJ
admet-698	55	15	compound	compound	NOUN
admet-698	55	16	salt	salt	NOUN
admet-698	55	17	and	and	CCONJ
admet-698	55	18	the	the	DET
admet-698	55	19	neutral	neutral	ADJ
admet-698	55	20	free	free	ADJ
admet-698	55	21	-	-	PUNCT
admet-698	55	22	acid	acid	ADJ
admet-698	55	23	/	/	SYM
admet-698	55	24	base	base	NOUN
admet-698	55	25	form	form	NOUN
admet-698	55	26	of	of	ADP
admet-698	55	27	the	the	DET
admet-698	55	28	solid	solid	ADJ
admet-698	55	29	(	(	PUNCT
admet-698	55	30	at	at	ADP
admet-698	55	31	the	the	DET
admet-698	55	32	ph	ph	NOUN
admet-698	55	33	called	call	VERB
admet-698	55	34	‘	'	PUNCT
admet-698	55	35	phmax	phmax	NOUN
admet-698	55	36	’	'	PUNCT
admet-698	55	37	)	)	PUNCT
admet-698	55	38	.	.	PUNCT
admet-698	56	1	solid	solid	ADJ
admet-698	56	2	state	state	NOUN
admet-698	56	3	characterization	characterization	NOUN
admet-698	56	4	of	of	ADP
admet-698	56	5	the	the	DET
admet-698	56	6	solid(s	solid(s	NOUN
admet-698	56	7	)	)	PUNCT
admet-698	56	8	and	and	CCONJ
admet-698	56	9	the	the	DET
admet-698	56	10	measurement	measurement	NOUN
admet-698	56	11	of	of	ADP
admet-698	56	12	ph	ph	NOUN
admet-698	56	13	would	would	AUX
admet-698	56	14	be	be	AUX
admet-698	56	15	highly	highly	ADV
admet-698	56	16	beneficial	beneficial	ADJ
admet-698	56	17	.	.	PUNCT
admet-698	57	1	(	(	PUNCT
admet-698	57	2	v	v	NOUN
admet-698	57	3	)	)	PUNCT
admet-698	57	4	when	when	SCONJ
admet-698	57	5	a	a	DET
admet-698	57	6	buffer	buffer	NOUN
admet-698	57	7	medium	medium	NOUN
admet-698	57	8	is	be	AUX
admet-698	57	9	used	use	VERB
admet-698	57	10	,	,	PUNCT
admet-698	57	11	the	the	DET
admet-698	57	12	analysis	analysis	NOUN
admet-698	57	13	of	of	ADP
admet-698	57	14	the	the	DET
admet-698	57	15	solution	solution	NOUN
admet-698	57	16	and	and	CCONJ
admet-698	57	17	solid	solid	ADJ
admet-698	57	18	states	state	NOUN
admet-698	57	19	can	can	AUX
admet-698	57	20	be	be	AUX
admet-698	57	21	complicated	complicate	VERB
admet-698	57	22	,	,	PUNCT
admet-698	57	23	as	as	SCONJ
admet-698	57	24	water	water	NOUN
admet-698	57	25	-	-	PUNCT
admet-698	57	26	soluble	soluble	ADJ
admet-698	57	27	drug	drug	NOUN
admet-698	57	28	-	-	PUNCT
admet-698	57	29	buffer	buffer	NOUN
admet-698	57	30	complexes	complex	NOUN
admet-698	57	31	or	or	CCONJ
admet-698	57	32	aggregates	aggregate	NOUN
admet-698	57	33	may	may	AUX
admet-698	57	34	form	form	VERB
admet-698	57	35	[	[	X
admet-698	57	36	10	10	NUM
admet-698	57	37	]	]	PUNCT
admet-698	57	38	.	.	PUNCT
admet-698	58	1	in	in	ADP
admet-698	58	2	a	a	DET
admet-698	58	3	supersaturated	supersaturated	ADJ
admet-698	58	4	solution	solution	NOUN
admet-698	58	5	,	,	PUNCT
admet-698	58	6	drug	drug	NOUN
admet-698	58	7	molecules	molecule	NOUN
admet-698	58	8	may	may	AUX
admet-698	58	9	self	self	NOUN
admet-698	58	10	-	-	PUNCT
admet-698	58	11	associate	associate	NOUN
admet-698	58	12	as	as	ADP
admet-698	58	13	sub	sub	ADJ
admet-698	58	14	-	-	ADJ
admet-698	58	15	micellar	micellar	ADJ
admet-698	58	16	aggregates	aggregate	NOUN
admet-698	58	17	,	,	PUNCT
admet-698	58	18	particularly	particularly	ADV
admet-698	58	19	if	if	SCONJ
admet-698	58	20	they	they	PRON
admet-698	58	21	are	be	AUX
admet-698	58	22	surface	surface	NOUN
admet-698	58	23	-	-	PUNCT
admet-698	58	24	active	active	ADJ
admet-698	59	1	[	[	X
admet-698	59	2	11,12	11,12	NUM
admet-698	59	3	]	]	PUNCT
admet-698	59	4	.	.	PUNCT
admet-698	60	1	for	for	ADP
admet-698	60	2	bases	basis	NOUN
admet-698	60	3	introduced	introduce	VERB
admet-698	60	4	as	as	ADP
admet-698	60	5	drug	drug	NOUN
admet-698	60	6	salts	salt	NOUN
admet-698	60	7	into	into	ADP
admet-698	60	8	a	a	DET
admet-698	60	9	high	high	ADJ
admet-698	60	10	-	-	PUNCT
admet-698	60	11	ph	ph	NOUN
admet-698	60	12	solution	solution	NOUN
admet-698	60	13	,	,	PUNCT
admet-698	60	14	the	the	DET
admet-698	60	15	charged	charge	VERB
admet-698	60	16	drug	drug	NOUN
admet-698	60	17	in	in	ADP
admet-698	60	18	the	the	DET
admet-698	60	19	supersaturated	supersaturated	ADJ
admet-698	60	20	solution	solution	NOUN
admet-698	60	21	can	can	AUX
admet-698	60	22	disproportionate	disproportionate	VERB
admet-698	60	23	into	into	ADP
admet-698	60	24	oil	oil	NOUN
admet-698	60	25	or	or	CCONJ
admet-698	60	26	undergo	undergo	VERB
admet-698	60	27	precipitation	precipitation	NOUN
admet-698	60	28	into	into	ADP
admet-698	60	29	an	an	DET
admet-698	60	30	amorphous	amorphous	ADJ
admet-698	60	31	solid	solid	NOUN
admet-698	60	32	,	,	PUNCT
admet-698	60	33	along	along	ADP
admet-698	60	34	with	with	ADP
admet-698	60	35	which	which	PRON
admet-698	60	36	charged	charge	VERB
admet-698	60	37	water	water	NOUN
admet-698	60	38	-	-	PUNCT
admet-698	60	39	soluble	soluble	ADJ
admet-698	60	40	aggregates	aggregate	NOUN
admet-698	60	41	may	may	AUX
admet-698	60	42	co	co	VERB
admet-698	60	43	-	-	VERB
admet-698	60	44	exist	exist	VERB
admet-698	60	45	[	[	X
admet-698	60	46	10	10	NUM
admet-698	60	47	-	-	SYM
admet-698	60	48	13	13	NUM
admet-698	60	49	]	]	PUNCT
admet-698	60	50	.	.	PUNCT
admet-698	61	1	given	give	VERB
admet-698	61	2	enough	enough	ADJ
admet-698	61	3	time	time	NOUN
admet-698	61	4	,	,	PUNCT
admet-698	61	5	the	the	DET
admet-698	61	6	multiple	multiple	ADJ
admet-698	61	7	phases	phase	NOUN
admet-698	61	8	are	be	AUX
admet-698	61	9	expected	expect	VERB
admet-698	61	10	to	to	PART
admet-698	61	11	undergo	undergo	VERB
admet-698	61	12	transformation	transformation	NOUN
admet-698	61	13	into	into	ADP
admet-698	61	14	a	a	DET
admet-698	61	15	thermodynamically	thermodynamically	ADV
admet-698	61	16	most	most	ADV
admet-698	61	17	-	-	PUNCT
admet-698	61	18	stable	stable	ADJ
admet-698	61	19	crystalline	crystalline	NOUN
admet-698	61	20	solid	solid	NOUN
admet-698	61	21	.	.	PUNCT
admet-698	62	1	good	good	ADJ
admet-698	62	2	understanding	understanding	NOUN
admet-698	62	3	of	of	ADP
admet-698	62	4	solution	solution	NOUN
admet-698	62	5	chemistry	chemistry	NOUN
admet-698	62	6	and	and	CCONJ
admet-698	62	7	solid	solid	ADJ
admet-698	62	8	state	state	NOUN
admet-698	62	9	characterization	characterization	NOUN
admet-698	62	10	is	be	AUX
admet-698	62	11	essential	essential	ADJ
admet-698	62	12	for	for	ADP
admet-698	62	13	correctly	correctly	ADV
admet-698	62	14	interpreting	interpret	VERB
admet-698	62	15	the	the	DET
admet-698	62	16	results	result	NOUN
admet-698	62	17	of	of	ADP
admet-698	62	18	solubility	solubility	NOUN
admet-698	62	19	measurements	measurement	NOUN
admet-698	62	20	,	,	PUNCT
admet-698	62	21	so	so	SCONJ
admet-698	62	22	that	that	SCONJ
admet-698	62	23	high	high	ADJ
admet-698	62	24	-	-	PUNCT
admet-698	62	25	quality	quality	NOUN
admet-698	62	26	intrinsic	intrinsic	ADJ
admet-698	62	27	solubility	solubility	NOUN
admet-698	62	28	data	datum	NOUN
admet-698	62	29	can	can	AUX
admet-698	62	30	be	be	AUX
admet-698	62	31	reported	report	VERB
admet-698	62	32	[	[	X
admet-698	62	33	3	3	NUM
admet-698	62	34	]	]	PUNCT
admet-698	62	35	.	.	PUNCT
admet-698	63	1	the	the	DET
admet-698	63	2	need	need	NOUN
admet-698	63	3	for	for	ADP
admet-698	63	4	high	high	ADJ
admet-698	63	5	-	-	PUNCT
admet-698	63	6	quality	quality	NOUN
admet-698	63	7	data	datum	NOUN
admet-698	63	8	in	in	ADP
admet-698	63	9	accurate	accurate	ADJ
admet-698	63	10	solubility	solubility	NOUN
admet-698	63	11	prediction	prediction	NOUN
admet-698	63	12	accurate	accurate	ADJ
admet-698	63	13	prediction	prediction	NOUN
admet-698	63	14	of	of	ADP
admet-698	63	15	the	the	DET
admet-698	63	16	intrinsic	intrinsic	ADJ
admet-698	63	17	solubility	solubility	NOUN
admet-698	63	18	of	of	ADP
admet-698	63	19	druglike	druglike	ADJ
admet-698	63	20	molecules	molecule	NOUN
admet-698	63	21	[	[	X
admet-698	63	22	2	2	NUM
admet-698	63	23	]	]	PUNCT
admet-698	63	24	requires	require	VERB
admet-698	63	25	that	that	SCONJ
admet-698	63	26	(	(	PUNCT
admet-698	63	27	a	a	X
admet-698	63	28	)	)	PUNCT
admet-698	63	29	the	the	DET
admet-698	63	30	log	log	NOUN
admet-698	63	31	s0	s0	PROPN
admet-698	63	32	values	value	NOUN
admet-698	63	33	used	use	VERB
admet-698	63	34	to	to	PART
admet-698	63	35	train	train	VERB
admet-698	63	36	the	the	DET
admet-698	63	37	prediction	prediction	NOUN
admet-698	63	38	method	method	NOUN
admet-698	63	39	are	be	AUX
admet-698	63	40	of	of	ADP
admet-698	63	41	high	high	ADJ
admet-698	63	42	quality	quality	NOUN
admet-698	63	43	(	(	PUNCT
admet-698	63	44	with	with	ADP
admet-698	63	45	water	water	NOUN
admet-698	63	46	solubility	solubility	NOUN
admet-698	63	47	values	value	NOUN
admet-698	63	48	,	,	PUNCT
admet-698	63	49	log	log	PROPN
admet-698	63	50	sw	sw	PROPN
admet-698	63	51	,	,	PUNCT
admet-698	63	52	or	or	CCONJ
admet-698	63	53	values	value	NOUN
admet-698	63	54	measured	measure	VERB
admet-698	63	55	at	at	ADP
admet-698	63	56	a	a	DET
admet-698	63	57	particular	particular	ADJ
admet-698	63	58	ph	ph	NOUN
admet-698	63	59	,	,	PUNCT
admet-698	63	60	log	log	PROPN
admet-698	63	61	sph	sph	PROPN
admet-698	63	62	,	,	PUNCT
admet-698	63	63	properly	properly	ADV
admet-698	63	64	corrected	correct	VERB
admet-698	63	65	for	for	ADP
admet-698	63	66	ionization	ionization	NOUN
admet-698	63	67	[	[	X
admet-698	63	68	14	14	NUM
admet-698	63	69	]	]	PUNCT
admet-698	63	70	and	and	CCONJ
admet-698	63	71	with	with	ADP
admet-698	63	72	all	all	DET
admet-698	63	73	solubility	solubility	NOUN
admet-698	63	74	values	value	NOUN
admet-698	63	75	referring	refer	VERB
admet-698	63	76	to	to	ADP
admet-698	63	77	the	the	DET
admet-698	63	78	same	same	ADJ
admet-698	63	79	temperature	temperature	NOUN
admet-698	63	80	[	[	X
admet-698	63	81	15	15	NUM
admet-698	63	82	]	]	NUM
admet-698	63	83	)	)	PUNCT
admet-698	63	84	,	,	PUNCT
admet-698	63	85	and	and	CCONJ
admet-698	63	86	(	(	PUNCT
admet-698	63	87	b	b	X
admet-698	63	88	)	)	PUNCT
admet-698	63	89	the	the	DET
admet-698	63	90	compounds	compound	NOUN
admet-698	63	91	in	in	ADP
admet-698	63	92	the	the	DET
admet-698	63	93	training	training	NOUN
admet-698	63	94	set	set	NOUN
admet-698	63	95	cover	cover	VERB
admet-698	63	96	the	the	DET
admet-698	63	97	druglike	druglike	ADJ
admet-698	63	98	chemical	chemical	NOUN
admet-698	63	99	space	space	NOUN
admet-698	63	100	of	of	ADP
admet-698	63	101	the	the	DET
admet-698	63	102	test	test	NOUN
admet-698	63	103	set	set	NOUN
admet-698	63	104	of	of	ADP
admet-698	63	105	compounds	compound	NOUN
admet-698	63	106	.	.	PUNCT
admet-698	64	1	these	these	DET
admet-698	64	2	two	two	NUM
admet-698	64	3	important	important	ADJ
admet-698	64	4	notions	notion	NOUN
admet-698	64	5	became	become	VERB
admet-698	64	6	the	the	DET
admet-698	64	7	focus	focus	NOUN
admet-698	64	8	of	of	ADP
admet-698	64	9	a	a	DET
admet-698	64	10	number	number	NOUN
admet-698	64	11	of	of	ADP
admet-698	64	12	studies	study	NOUN
admet-698	64	13	since	since	SCONJ
admet-698	64	14	2008	2008	NUM
admet-698	64	15	,	,	PUNCT
admet-698	64	16	spurred	spur	VERB
admet-698	64	17	by	by	ADP
admet-698	64	18	the	the	DET
admet-698	64	19	publications	publication	NOUN
admet-698	64	20	of	of	ADP
admet-698	64	21	llinàs	llinà	NOUN
admet-698	64	22	et	et	PROPN
admet-698	64	23	al	al	PROPN
admet-698	64	24	.	.	PUNCT
admet-698	65	1	[	[	X
admet-698	65	2	16	16	NUM
admet-698	65	3	]	]	PUNCT
admet-698	65	4	and	and	CCONJ
admet-698	65	5	hopfinger	hopfinger	PROPN
admet-698	65	6	et	et	PROPN
admet-698	65	7	al	al	PROPN
admet-698	65	8	.	.	PUNCT
admet-698	66	1	[	[	X
admet-698	66	2	17	17	NUM
admet-698	66	3	]	]	PUNCT
admet-698	66	4	.	.	PUNCT
admet-698	67	1	these	these	DET
admet-698	67	2	authors	author	NOUN
admet-698	67	3	introduced	introduce	VERB
admet-698	67	4	the	the	DET
admet-698	67	5	‘	'	PUNCT
admet-698	67	6	solubility	solubility	NOUN
admet-698	67	7	challenge	challenge	NOUN
admet-698	67	8	,	,	PUNCT
admet-698	67	9	’	'	PUNCT
admet-698	67	10	a	a	DET
admet-698	67	11	competition	competition	NOUN
admet-698	67	12	to	to	PART
admet-698	67	13	probe	probe	VERB
admet-698	67	14	the	the	DET
admet-698	67	15	limits	limit	NOUN
admet-698	67	16	of	of	ADP
admet-698	67	17	prediction	prediction	NOUN
admet-698	67	18	methods	method	NOUN
admet-698	67	19	.	.	PUNCT
admet-698	68	1	the	the	DET
admet-698	68	2	cheqsol	cheqsol	ADJ
admet-698	68	3	method	method	NOUN
admet-698	68	4	was	be	AUX
admet-698	68	5	used	use	VERB
admet-698	68	6	to	to	PART
admet-698	68	7	measure	measure	VERB
admet-698	68	8	the	the	DET
admet-698	68	9	log	log	NOUN
admet-698	68	10	s0	s0	NOUN
admet-698	68	11	of	of	ADP
admet-698	68	12	132	132	NUM
admet-698	68	13	structurally	structurally	ADV
admet-698	68	14	diverse	diverse	ADJ
admet-698	68	15	drugs	drug	NOUN
admet-698	68	16	.	.	PUNCT
admet-698	69	1	the	the	DET
admet-698	69	2	log	log	NOUN
admet-698	69	3	s0	s0	PROPN
admet-698	69	4	values	value	NOUN
admet-698	69	5	of	of	ADP
admet-698	69	6	100	100	NUM
admet-698	69	7	molecules	molecule	NOUN
admet-698	69	8	were	be	AUX
admet-698	69	9	offered	offer	VERB
admet-698	69	10	as	as	ADP
admet-698	69	11	the	the	DET
admet-698	69	12	training	training	NOUN
admet-698	69	13	set	set	NOUN
admet-698	69	14	for	for	ADP
admet-698	69	15	the	the	DET
admet-698	69	16	prediction	prediction	NOUN
admet-698	69	17	of	of	ADP
admet-698	69	18	an	an	DET
admet-698	69	19	external	external	ADJ
admet-698	69	20	test	test	NOUN
admet-698	69	21	set	set	NOUN
admet-698	69	22	of	of	ADP
admet-698	69	23	32	32	NUM
admet-698	69	24	molecules	molecule	NOUN
admet-698	69	25	(	(	PUNCT
admet-698	69	26	not	not	PART
admet-698	69	27	found	find	VERB
admet-698	69	28	in	in	ADP
admet-698	69	29	the	the	DET
admet-698	69	30	training	training	NOUN
admet-698	69	31	set	set	NOUN
admet-698	69	32	)	)	PUNCT
admet-698	69	33	,	,	PUNCT
admet-698	69	34	whose	whose	DET
admet-698	69	35	values	value	NOUN
admet-698	69	36	were	be	AUX
admet-698	69	37	not	not	PART
admet-698	69	38	revealed	reveal	VERB
admet-698	69	39	before	before	ADP
admet-698	69	40	the	the	DET
admet-698	69	41	completion	completion	NOUN
admet-698	69	42	of	of	ADP
admet-698	69	43	the	the	DET
admet-698	69	44	competition	competition	NOUN
admet-698	69	45	.	.	PUNCT
admet-698	70	1	in	in	ADP
admet-698	70	2	a	a	DET
admet-698	70	3	number	number	NOUN
admet-698	70	4	of	of	ADP
admet-698	70	5	earlier	early	ADJ
admet-698	70	6	studies	study	NOUN
admet-698	70	7	,	,	PUNCT
admet-698	70	8	it	it	PRON
admet-698	70	9	was	be	AUX
admet-698	70	10	suggested	suggest	VERB
admet-698	70	11	that	that	SCONJ
admet-698	70	12	the	the	DET
admet-698	70	13	typical	typical	ADJ
admet-698	70	14	error	error	NOUN
admet-698	70	15	in	in	ADP
admet-698	70	16	measured	measure	VERB
admet-698	70	17	aqueous	aqueous	ADJ
admet-698	70	18	solubility	solubility	NOUN
admet-698	70	19	is	be	AUX
admet-698	70	20	~0.6	~0.6	NUM
admet-698	70	21	log	log	NOUN
admet-698	70	22	unit	unit	NOUN
admet-698	70	23	or	or	CCONJ
admet-698	70	24	higher	high	ADJ
admet-698	70	25	,	,	PUNCT
admet-698	70	26	when	when	SCONJ
admet-698	70	27	the	the	DET
admet-698	70	28	solubility	solubility	NOUN
admet-698	70	29	values	value	NOUN
admet-698	70	30	were	be	AUX
admet-698	70	31	collected	collect	VERB
admet-698	70	32	from	from	ADP
admet-698	70	33	many	many	ADJ
admet-698	70	34	published	publish	VERB
admet-698	70	35	sources	source	NOUN
admet-698	70	36	[	[	X
admet-698	70	37	18	18	NUM
admet-698	70	38	]	]	PUNCT
admet-698	70	39	.	.	PUNCT
admet-698	71	1	this	this	PRON
admet-698	71	2	suggested	suggest	VERB
admet-698	71	3	that	that	SCONJ
admet-698	71	4	the	the	DET
admet-698	71	5	quality	quality	NOUN
admet-698	71	6	of	of	ADP
admet-698	71	7	prediction	prediction	NOUN
admet-698	71	8	methods	method	NOUN
admet-698	71	9	was	be	AUX
admet-698	71	10	approaching	approach	VERB
admet-698	71	11	the	the	DET
admet-698	71	12	experimental	experimental	ADJ
admet-698	71	13	limit	limit	NOUN
admet-698	71	14	.	.	PUNCT
admet-698	72	1	however	however	ADV
admet-698	72	2	,	,	PUNCT
admet-698	72	3	in	in	ADP
admet-698	72	4	the	the	DET
admet-698	72	5	admet	admet	PROPN
admet-698	72	6	&	&	CCONJ
admet-698	72	7	dmpk	dmpk	PROPN
admet-698	72	8	7(3	7(3	NUM
admet-698	72	9	)	)	PUNCT
admet-698	72	10	(	(	PUNCT
admet-698	72	11	2019	2019	NUM
admet-698	72	12	)	)	PUNCT
admet-698	72	13	210	210	NUM
admet-698	72	14	-	-	SYM
admet-698	72	15	219	219	NUM
admet-698	72	16	multi	multi	ADJ
admet-698	72	17	-	-	ADJ
admet-698	72	18	lab	lab	ADJ
admet-698	72	19	log	log	NOUN
admet-698	72	20	s0	s0	PROPN
admet-698	72	21	measurement	measurement	PROPN
admet-698	72	22	reproducibility	reproducibility	NOUN
admet-698	72	23	in	in	ADP
admet-698	72	24	cheqsol	cheqsol	NOUN
admet-698	72	25	and	and	CCONJ
admet-698	72	26	shake	shake	NOUN
admet-698	72	27	-	-	PUNCT
admet-698	72	28	flask	flask	NOUN
admet-698	72	29	methods	method	NOUN
admet-698	72	30	doi	doi	NOUN
admet-698	72	31	:	:	PUNCT
admet-698	72	32	10.5599	10.5599	NUM
admet-698	72	33	/	/	SYM
admet-698	72	34	admet.698	admet.698	ADJ
admet-698	72	35	213	213	NUM
admet-698	72	36	solubility	solubility	NOUN
admet-698	72	37	challenge	challenge	NOUN
admet-698	72	38	competition	competition	NOUN
admet-698	72	39	all	all	PRON
admet-698	72	40	of	of	ADP
admet-698	72	41	the	the	DET
admet-698	72	42	values	value	NOUN
admet-698	72	43	came	come	VERB
admet-698	72	44	from	from	ADP
admet-698	72	45	one	one	NUM
admet-698	72	46	laboratory	laboratory	NOUN
admet-698	72	47	,	,	PUNCT
admet-698	72	48	and	and	CCONJ
admet-698	72	49	the	the	DET
admet-698	72	50	intralaboratory	intralaboratory	ADJ
admet-698	72	51	precision	precision	NOUN
admet-698	72	52	(	(	PUNCT
admet-698	72	53	repetitive	repetitive	ADJ
admet-698	72	54	measurements	measurement	NOUN
admet-698	72	55	of	of	ADP
admet-698	72	56	the	the	DET
admet-698	72	57	same	same	ADJ
admet-698	72	58	sample	sample	NOUN
admet-698	72	59	by	by	ADP
admet-698	72	60	the	the	DET
admet-698	72	61	same	same	ADJ
admet-698	72	62	chemist	chemist	NOUN
admet-698	72	63	,	,	PUNCT
admet-698	72	64	using	use	VERB
admet-698	72	65	the	the	DET
admet-698	72	66	same	same	ADJ
admet-698	72	67	instrument	instrument	NOUN
admet-698	72	68	)	)	PUNCT
admet-698	72	69	of	of	ADP
admet-698	72	70	the	the	DET
admet-698	72	71	cheqsol	cheqsol	ADJ
admet-698	72	72	data	datum	NOUN
admet-698	72	73	was	be	AUX
admet-698	72	74	reported	report	VERB
admet-698	72	75	to	to	PART
admet-698	72	76	be	be	AUX
admet-698	72	77	sd	sd	ADP
admet-698	72	78	=	=	SYM
admet-698	72	79	0.05	0.05	NUM
admet-698	72	80	log	log	NOUN
admet-698	72	81	unit	unit	NOUN
admet-698	72	82	.	.	PUNCT
admet-698	73	1	it	it	PRON
admet-698	73	2	was	be	AUX
admet-698	73	3	not	not	PART
admet-698	73	4	known	know	VERB
admet-698	73	5	what	what	PRON
admet-698	73	6	the	the	DET
admet-698	73	7	expected	expect	VERB
admet-698	73	8	interlaboratory	interlaboratory	ADJ
admet-698	73	9	precision	precision	NOUN
admet-698	73	10	would	would	AUX
admet-698	73	11	be	be	AUX
admet-698	73	12	,	,	PUNCT
admet-698	73	13	given	give	VERB
admet-698	73	14	the	the	DET
admet-698	73	15	unknown	unknown	ADJ
admet-698	73	16	systematic	systematic	ADJ
admet-698	73	17	errors	error	NOUN
admet-698	73	18	that	that	PRON
admet-698	73	19	might	might	AUX
admet-698	73	20	affect	affect	VERB
admet-698	73	21	the	the	DET
admet-698	73	22	accuracy	accuracy	NOUN
admet-698	73	23	of	of	ADP
admet-698	73	24	results	result	NOUN
admet-698	73	25	.	.	PUNCT
admet-698	74	1	for	for	ADP
admet-698	74	2	example	example	NOUN
admet-698	74	3	,	,	PUNCT
admet-698	74	4	when	when	SCONJ
admet-698	74	5	125	125	NUM
admet-698	74	6	published	publish	VERB
admet-698	74	7	cheqsol	cheqsol	NOUN
admet-698	74	8	values	value	NOUN
admet-698	74	9	were	be	AUX
admet-698	74	10	compared	compare	VERB
admet-698	74	11	in	in	ADP
admet-698	74	12	2015	2015	NUM
admet-698	74	13	to	to	ADP
admet-698	74	14	those	those	PRON
admet-698	74	15	obtained	obtain	VERB
admet-698	74	16	by	by	ADP
admet-698	74	17	the	the	DET
admet-698	74	18	ssf	ssf	NOUN
admet-698	74	19	method	method	NOUN
admet-698	74	20	,	,	PUNCT
admet-698	74	21	it	it	PRON
admet-698	74	22	was	be	AUX
admet-698	74	23	reported	report	VERB
admet-698	74	24	that	that	SCONJ
admet-698	74	25	r	r	NOUN
admet-698	74	26	2	2	NUM
admet-698	74	27	=	=	SYM
admet-698	74	28	0.90	0.90	NUM
admet-698	74	29	,	,	PUNCT
admet-698	74	30	prediction	prediction	NOUN
admet-698	74	31	root	root	NOUN
admet-698	74	32	-	-	PUNCT
admet-698	74	33	mean	mean	ADJ
admet-698	74	34	-	-	PUNCT
admet-698	74	35	square	square	NOUN
admet-698	74	36	-	-	PUNCT
admet-698	74	37	error	error	NOUN
admet-698	74	38	,	,	PUNCT
admet-698	74	39	rmse	rmse	NOUN
admet-698	74	40	=	=	SYM
admet-698	74	41	0.52	0.52	NUM
admet-698	74	42	log	log	NOUN
admet-698	74	43	unit	unit	NOUN
admet-698	74	44	,	,	PUNCT
admet-698	74	45	and	and	CCONJ
admet-698	74	46	there	there	PRON
admet-698	74	47	was	be	VERB
admet-698	74	48	a	a	DET
admet-698	74	49	slight	slight	ADJ
admet-698	74	50	bias	bias	NOUN
admet-698	74	51	of	of	ADP
admet-698	74	52	-0.13	-0.13	NUM
admet-698	74	53	log	log	NOUN
admet-698	74	54	unit	unit	NOUN
admet-698	74	55	[	[	X
admet-698	74	56	19	19	NUM
admet-698	74	57	]	]	PUNCT
admet-698	74	58	.	.	PUNCT
admet-698	75	1	the	the	DET
admet-698	75	2	values	value	NOUN
admet-698	75	3	in	in	ADP
admet-698	75	4	the	the	DET
admet-698	75	5	comparison	comparison	NOUN
admet-698	75	6	came	come	VERB
admet-698	75	7	from	from	ADP
admet-698	75	8	the	the	DET
admet-698	75	9	wiki	wiki	NOUN
admet-698	75	10	-	-	PUNCT
admet-698	75	11	ps0	ps0	ADJ
admet-698	75	12	database	database	NOUN
admet-698	75	13	(	(	PUNCT
admet-698	75	14	in	in	ADP
admet-698	75	15	-	-	PUNCT
admet-698	75	16	adme	adme	NOUN
admet-698	75	17	research	research	NOUN
admet-698	75	18	)	)	PUNCT
admet-698	75	19	,	,	PUNCT
admet-698	75	20	which	which	PRON
admet-698	75	21	at	at	ADP
admet-698	75	22	that	that	DET
admet-698	75	23	time	time	NOUN
admet-698	75	24	contained	contain	VERB
admet-698	75	25	4557	4557	NUM
admet-698	75	26	log	log	NOUN
admet-698	75	27	s0	s0	PROPN
admet-698	75	28	entries	entry	NOUN
admet-698	75	29	.	.	PUNCT
admet-698	76	1	the	the	DET
admet-698	76	2	database	database	NOUN
admet-698	76	3	now	now	ADV
admet-698	76	4	has	have	VERB
admet-698	76	5	6355	6355	NUM
admet-698	76	6	entries	entry	NOUN
admet-698	76	7	,	,	PUNCT
admet-698	76	8	with	with	ADP
admet-698	76	9	many	many	ADJ
admet-698	76	10	newly	newly	ADV
admet-698	76	11	added	add	VERB
admet-698	76	12	cheqsol	cheqsol	NOUN
admet-698	76	13	and	and	CCONJ
admet-698	76	14	ssf	ssf	NOUN
admet-698	76	15	values	value	NOUN
admet-698	76	16	.	.	PUNCT
admet-698	77	1	it	it	PRON
admet-698	77	2	was	be	AUX
admet-698	77	3	thus	thus	ADV
admet-698	77	4	of	of	ADP
admet-698	77	5	interest	interest	NOUN
admet-698	77	6	to	to	PART
admet-698	77	7	update	update	VERB
admet-698	77	8	and	and	CCONJ
admet-698	77	9	better	well	ADV
admet-698	77	10	characterize	characterize	VERB
admet-698	77	11	the	the	DET
admet-698	77	12	comparison	comparison	NOUN
admet-698	77	13	of	of	ADP
admet-698	77	14	data	datum	NOUN
admet-698	77	15	quality	quality	NOUN
admet-698	77	16	between	between	ADP
admet-698	77	17	the	the	DET
admet-698	77	18	cheqsol	cheqsol	NOUN
admet-698	77	19	and	and	CCONJ
admet-698	77	20	the	the	DET
admet-698	77	21	‘	'	PUNCT
admet-698	77	22	gold	gold	ADJ
admet-698	77	23	standard	standard	NOUN
admet-698	77	24	’	'	PUNCT
admet-698	77	25	saturation	saturation	NOUN
admet-698	77	26	shake	shake	NOUN
admet-698	77	27	-	-	PUNCT
admet-698	77	28	flask	flask	NOUN
admet-698	77	29	methods	method	NOUN
admet-698	77	30	.	.	PUNCT
admet-698	78	1	in	in	ADP
admet-698	78	2	parallel	parallel	NOUN
admet-698	78	3	,	,	PUNCT
admet-698	78	4	armed	arm	VERB
admet-698	78	5	with	with	ADP
admet-698	78	6	new	new	ADJ
admet-698	78	7	curated	curate	VERB
admet-698	78	8	data	datum	NOUN
admet-698	78	9	,	,	PUNCT
admet-698	78	10	the	the	DET
admet-698	78	11	second	second	ADJ
admet-698	78	12	solubility	solubility	NOUN
admet-698	78	13	challenge	challenge	NOUN
admet-698	78	14	has	have	AUX
admet-698	78	15	just	just	ADV
admet-698	78	16	been	be	AUX
admet-698	78	17	announced	announce	VERB
admet-698	78	18	[	[	PUNCT
admet-698	78	19	2	2	NUM
admet-698	78	20	]	]	PUNCT
admet-698	78	21	,	,	PUNCT
admet-698	78	22	with	with	SCONJ
admet-698	78	23	the	the	DET
admet-698	78	24	prediction	prediction	NOUN
admet-698	78	25	submission	submission	NOUN
admet-698	78	26	deadline	deadline	NOUN
admet-698	78	27	set	set	VERB
admet-698	78	28	to	to	ADP
admet-698	78	29	8	8	NUM
admet-698	78	30	september	september	PROPN
admet-698	78	31	2019	2019	NUM
admet-698	78	32	,	,	PUNCT
admet-698	78	33	the	the	DET
admet-698	78	34	day	day	NOUN
admet-698	78	35	before	before	SCONJ
admet-698	78	36	the	the	DET
admet-698	78	37	iapc8	iapc8	NOUN
admet-698	78	38	conference	conference	NOUN
admet-698	78	39	starts	start	VERB
admet-698	78	40	.	.	PUNCT
admet-698	79	1	the	the	DET
admet-698	79	2	excel	excel	ADJ
admet-698	79	3	submission	submission	NOUN
admet-698	79	4	form	form	NOUN
admet-698	79	5	in	in	ADP
admet-698	79	6	supporting	support	VERB
admet-698	79	7	info	info	NOUN
admet-698	79	8	at	at	ADP
admet-698	79	9	https://pubs.acs.org/doi/suppl/10.1021/acs.jcim.9b00345	https://pubs.acs.org/doi/suppl/10.1021/acs.jcim.9b00345	PROPN
admet-698	79	10	is	be	AUX
admet-698	79	11	freely	freely	ADV
admet-698	79	12	downloadable	downloadable	ADJ
admet-698	79	13	for	for	ADP
admet-698	79	14	those	those	PRON
admet-698	79	15	interested	interested	ADJ
admet-698	79	16	to	to	PART
admet-698	79	17	participate	participate	VERB
admet-698	79	18	.	.	PUNCT
admet-698	80	1	the	the	DET
admet-698	80	2	data	datum	NOUN
admet-698	80	3	described	describe	VERB
admet-698	80	4	below	below	ADV
admet-698	80	5	could	could	AUX
admet-698	80	6	be	be	AUX
admet-698	80	7	a	a	DET
admet-698	80	8	useful	useful	ADJ
admet-698	80	9	addition	addition	NOUN
admet-698	80	10	to	to	ADP
admet-698	80	11	other	other	ADJ
admet-698	80	12	druglike	druglike	NOUN
admet-698	80	13	training	training	NOUN
admet-698	80	14	sets	set	NOUN
admet-698	80	15	currently	currently	ADV
admet-698	80	16	in	in	ADP
admet-698	80	17	circulation	circulation	NOUN
admet-698	80	18	.	.	PUNCT
admet-698	81	1	method	method	PROPN
admet-698	81	2	data	data	PROPN
admet-698	81	3	source	source	NOUN
admet-698	81	4	:	:	PUNCT
admet-698	81	5	wiki	wiki	NOUN
admet-698	81	6	-	-	PUNCT
admet-698	81	7	ps0	ps0	ADJ
admet-698	81	8	database	database	NOUN
admet-698	81	9	the	the	DET
admet-698	81	10	ongoing	ongoing	ADJ
admet-698	81	11	wiki	wiki	NOUN
admet-698	81	12	-	-	PUNCT
admet-698	81	13	ps0	ps0	ADJ
admet-698	81	14	database	database	NOUN
admet-698	81	15	project	project	NOUN
admet-698	82	1	[	[	X
admet-698	82	2	2,3,15,19	2,3,15,19	NUM
admet-698	82	3	]	]	PUNCT
admet-698	82	4	,	,	PUNCT
admet-698	82	5	which	which	PRON
admet-698	82	6	started	start	VERB
admet-698	82	7	in	in	ADP
admet-698	82	8	2011	2011	NUM
admet-698	82	9	,	,	PUNCT
admet-698	82	10	now	now	ADV
admet-698	82	11	has	have	VERB
admet-698	82	12	6355	6355	NUM
admet-698	82	13	log	log	NOUN
admet-698	82	14	s0	s0	NOUN
admet-698	82	15	entries	entry	NOUN
admet-698	82	16	for	for	ADP
admet-698	82	17	3014	3014	NUM
admet-698	82	18	different	different	ADJ
admet-698	82	19	drug	drug	NOUN
admet-698	82	20	-	-	PUNCT
admet-698	82	21	relevant	relevant	ADJ
admet-698	82	22	molecules	molecule	NOUN
admet-698	82	23	(	(	PUNCT
admet-698	82	24	solids	solid	NOUN
admet-698	82	25	at	at	ADP
admet-698	82	26	room	room	NOUN
admet-698	82	27	temperature	temperature	NOUN
admet-698	82	28	)	)	PUNCT
admet-698	82	29	,	,	PUNCT
admet-698	82	30	drawing	draw	VERB
admet-698	82	31	on	on	ADP
admet-698	82	32	the	the	DET
admet-698	82	33	study	study	NOUN
admet-698	82	34	of	of	ADP
admet-698	82	35	1325	1325	NUM
admet-698	82	36	publications	publication	NOUN
admet-698	82	37	.	.	PUNCT
admet-698	83	1	the	the	DET
admet-698	83	2	overall	overall	ADJ
admet-698	83	3	interlaboratory	interlaboratory	ADJ
admet-698	83	4	standard	standard	ADJ
admet-698	83	5	deviation	deviation	NOUN
admet-698	83	6	,	,	PUNCT
admet-698	83	7	sdi	sdi	PROPN
admet-698	83	8	all	all	PRON
admet-698	83	9	=	=	NUM
admet-698	83	10	0.17	0.17	NUM
admet-698	83	11	log	log	NOUN
admet-698	83	12	unit	unit	NOUN
admet-698	83	13	,	,	PUNCT
admet-698	83	14	has	have	AUX
admet-698	83	15	been	be	AUX
admet-698	83	16	estimated	estimate	VERB
admet-698	83	17	from	from	ADP
admet-698	83	18	the	the	DET
admet-698	83	19	870	870	NUM
admet-698	83	20	molecules	molecule	NOUN
admet-698	83	21	for	for	ADP
admet-698	83	22	which	which	PRON
admet-698	83	23	solubility	solubility	NOUN
admet-698	83	24	was	be	AUX
admet-698	83	25	reported	report	VERB
admet-698	83	26	from	from	ADP
admet-698	83	27	two	two	NUM
admet-698	83	28	or	or	CCONJ
admet-698	83	29	more	more	ADV
admet-698	83	30	different	different	ADJ
admet-698	83	31	sources	source	NOUN
admet-698	83	32	(	(	PUNCT
admet-698	83	33	comprising	comprise	VERB
admet-698	83	34	4209	4209	NUM
admet-698	83	35	individual	individual	ADJ
admet-698	83	36	s0	s0	PROPN
admet-698	83	37	values	value	NOUN
admet-698	83	38	)	)	PUNCT
admet-698	83	39	,	,	PUNCT
admet-698	83	40	by	by	ADP
admet-698	83	41	taking	take	VERB
admet-698	83	42	the	the	DET
admet-698	83	43	average	average	NOUN
admet-698	83	44	of	of	ADP
admet-698	83	45	the	the	DET
admet-698	83	46	individual	individual	ADJ
admet-698	83	47	870	870	NUM
admet-698	83	48	sd	sd	NOUN
admet-698	83	49	values	value	NOUN
admet-698	83	50	.	.	PUNCT
admet-698	84	1	the	the	DET
admet-698	84	2	sdi	sdi	PROPN
admet-698	84	3	all	all	PRON
admet-698	84	4	,	,	PUNCT
admet-698	84	5	being	be	AUX
admet-698	84	6	lower	low	ADJ
admet-698	84	7	than	than	ADP
admet-698	84	8	the	the	DET
admet-698	84	9	older	old	ADJ
admet-698	84	10	estimate	estimate	NOUN
admet-698	84	11	of	of	ADP
admet-698	84	12	solubility	solubility	NOUN
admet-698	84	13	measurement	measurement	NOUN
admet-698	84	14	error	error	NOUN
admet-698	84	15	(	(	PUNCT
admet-698	84	16	~0.6	~0.6	NUM
admet-698	84	17	log	log	NOUN
admet-698	84	18	unit	unit	NOUN
admet-698	84	19	[	[	X
admet-698	84	20	18	18	NUM
admet-698	84	21	]	]	PUNCT
admet-698	84	22	)	)	PUNCT
admet-698	84	23	,	,	PUNCT
admet-698	84	24	indicates	indicate	VERB
admet-698	84	25	that	that	SCONJ
admet-698	84	26	(	(	PUNCT
admet-698	84	27	i	i	NOUN
admet-698	84	28	)	)	PUNCT
admet-698	84	29	when	when	SCONJ
admet-698	84	30	legacy	legacy	NOUN
admet-698	84	31	data	datum	NOUN
admet-698	84	32	are	be	AUX
admet-698	84	33	subjected	subject	VERB
admet-698	84	34	to	to	ADP
admet-698	84	35	critical	critical	ADJ
admet-698	84	36	analysis	analysis	NOUN
admet-698	84	37	,	,	PUNCT
admet-698	84	38	as	as	SCONJ
admet-698	84	39	recommended	recommend	VERB
admet-698	84	40	in	in	ADP
admet-698	84	41	[	[	X
admet-698	84	42	3,15,19	3,15,19	NUM
admet-698	84	43	]	]	PUNCT
admet-698	84	44	,	,	PUNCT
admet-698	84	45	improvements	improvement	NOUN
admet-698	84	46	in	in	ADP
admet-698	84	47	the	the	DET
admet-698	84	48	quality	quality	NOUN
admet-698	84	49	of	of	ADP
admet-698	84	50	the	the	DET
admet-698	84	51	extracted	extract	VERB
admet-698	84	52	log	log	NOUN
admet-698	84	53	s0	s0	PROPN
admet-698	84	54	data	datum	NOUN
admet-698	84	55	can	can	AUX
admet-698	84	56	be	be	AUX
admet-698	84	57	achieved	achieve	VERB
admet-698	84	58	,	,	PUNCT
admet-698	84	59	and	and	CCONJ
admet-698	84	60	(	(	PUNCT
admet-698	84	61	ii	ii	NOUN
admet-698	84	62	)	)	PUNCT
admet-698	84	63	there	there	PRON
admet-698	84	64	is	be	VERB
admet-698	84	65	room	room	NOUN
admet-698	84	66	for	for	ADP
admet-698	84	67	further	further	ADJ
admet-698	84	68	improvement	improvement	NOUN
admet-698	84	69	to	to	ADP
admet-698	84	70	the	the	DET
admet-698	84	71	current	current	ADJ
admet-698	84	72	prediction	prediction	NOUN
admet-698	84	73	methods	method	NOUN
admet-698	84	74	.	.	PUNCT
admet-698	85	1	alongside	alongside	ADP
admet-698	85	2	the	the	DET
admet-698	85	3	database	database	NOUN
admet-698	85	4	,	,	PUNCT
admet-698	85	5	the	the	DET
admet-698	85	6	pdisol	pdisol	ADJ
admet-698	85	7	-	-	PUNCT
admet-698	85	8	x	x	NOUN
admet-698	85	9	program	program	NOUN
admet-698	85	10	(	(	PUNCT
admet-698	85	11	in	in	ADP
admet-698	85	12	-	-	PUNCT
admet-698	85	13	adme	adme	NOUN
admet-698	85	14	research	research	NOUN
admet-698	85	15	)	)	PUNCT
admet-698	85	16	was	be	AUX
admet-698	85	17	designed	design	VERB
admet-698	85	18	to	to	PART
admet-698	85	19	interpret	interpret	VERB
admet-698	85	20	solubility	solubility	NOUN
admet-698	85	21	data	datum	NOUN
admet-698	85	22	and	and	CCONJ
admet-698	85	23	make	make	VERB
admet-698	85	24	temperature	temperature	NOUN
admet-698	85	25	corrections	correction	NOUN
admet-698	85	26	,	,	PUNCT
admet-698	85	27	to	to	PART
admet-698	85	28	produce	produce	VERB
admet-698	85	29	a	a	DET
admet-698	85	30	reliable	reliable	ADJ
admet-698	85	31	estimate	estimate	NOUN
admet-698	85	32	of	of	ADP
admet-698	85	33	the	the	DET
admet-698	85	34	underpinning	underpin	VERB
admet-698	85	35	log	log	NOUN
admet-698	85	36	s0	s0	PROPN
admet-698	86	1	[	[	X
admet-698	86	2	10,11,20	10,11,20	NUM
admet-698	86	3	]	]	PUNCT
admet-698	86	4	.	.	PUNCT
admet-698	87	1	results	result	NOUN
admet-698	87	2	there	there	PRON
admet-698	87	3	are	be	VERB
admet-698	87	4	233	233	NUM
admet-698	87	5	reported	report	VERB
admet-698	87	6	cheqsol	cheqsol	NOUN
admet-698	87	7	log	log	NOUN
admet-698	87	8	s0	s0	NOUN
admet-698	87	9	values	value	NOUN
admet-698	87	10	in	in	ADP
admet-698	87	11	the	the	DET
admet-698	87	12	wiki	wiki	NOUN
admet-698	87	13	-	-	PUNCT
admet-698	87	14	ps0	ps0	ADJ
admet-698	87	15	database	database	NOUN
admet-698	87	16	for	for	ADP
admet-698	87	17	145	145	NUM
admet-698	87	18	different	different	ADJ
admet-698	87	19	druglike	druglike	NOUN
admet-698	87	20	molecules	molecule	NOUN
admet-698	87	21	.	.	PUNCT
admet-698	88	1	for	for	ADP
admet-698	88	2	124	124	NUM
admet-698	88	3	of	of	ADP
admet-698	88	4	the	the	DET
admet-698	88	5	molecules	molecule	NOUN
admet-698	88	6	,	,	PUNCT
admet-698	88	7	there	there	PRON
admet-698	88	8	are	be	VERB
admet-698	88	9	838	838	NUM
admet-698	88	10	reported	report	VERB
admet-698	88	11	log	log	NOUN
admet-698	88	12	s0	s0	PROPN
admet-698	88	13	determined	determine	VERB
admet-698	88	14	mostly	mostly	ADV
admet-698	88	15	by	by	ADP
admet-698	88	16	the	the	DET
admet-698	88	17	ssf	ssf	NOUN
admet-698	88	18	method	method	NOUN
admet-698	88	19	.	.	PUNCT
admet-698	89	1	of	of	ADP
admet-698	89	2	the	the	DET
admet-698	89	3	838	838	NUM
admet-698	89	4	entries	entry	NOUN
admet-698	89	5	,	,	PUNCT
admet-698	89	6	298	298	NUM
admet-698	89	7	(	(	PUNCT
admet-698	89	8	36	36	NUM
admet-698	89	9	%	%	NOUN
admet-698	89	10	)	)	PUNCT
admet-698	89	11	were	be	AUX
admet-698	89	12	log	log	NOUN
admet-698	89	13	s0	s0	PROPN
admet-698	89	14	values	value	NOUN
admet-698	89	15	calculated	calculate	VERB
admet-698	89	16	from	from	ADP
admet-698	89	17	log	log	PROPN
admet-698	89	18	s	s	PROPN
admet-698	89	19	vs.	vs.	ADP
admet-698	89	20	ph	ph	ADJ
admet-698	89	21	data	datum	NOUN
admet-698	89	22	(	(	PUNCT
admet-698	89	23	using	use	VERB
admet-698	89	24	pdisol	pdisol	ADJ
admet-698	89	25	-	-	PUNCT
admet-698	89	26	x	x	NOUN
admet-698	89	27	)	)	PUNCT
admet-698	89	28	,	,	PUNCT
admet-698	89	29	based	base	VERB
admet-698	89	30	on	on	ADP
admet-698	89	31	a	a	DET
admet-698	89	32	total	total	NOUN
admet-698	89	33	of	of	ADP
admet-698	89	34	2925	2925	NUM
admet-698	89	35	individual	individual	ADJ
admet-698	89	36	log	log	NOUN
admet-698	89	37	sph	sph	PROPN
admet-698	89	38	measurments	measurment	NOUN
admet-698	89	39	.	.	PUNCT
admet-698	90	1	(	(	PUNCT
admet-698	90	2	for	for	ADP
admet-698	90	3	21	21	NUM
admet-698	90	4	of	of	ADP
admet-698	90	5	the	the	DET
admet-698	90	6	145	145	NUM
admet-698	90	7	molecules	molecule	NOUN
admet-698	90	8	,	,	PUNCT
admet-698	90	9	ssf	ssf	PROPN
admet-698	90	10	data	datum	NOUN
admet-698	90	11	have	have	AUX
admet-698	90	12	not	not	PART
admet-698	90	13	been	be	AUX
admet-698	90	14	located	locate	VERB
admet-698	90	15	in	in	ADP
admet-698	90	16	the	the	DET
admet-698	90	17	literature	literature	NOUN
admet-698	90	18	.	.	PUNCT
admet-698	90	19	)	)	PUNCT
admet-698	91	1	table	table	NOUN
admet-698	91	2	1	1	NUM
admet-698	91	3	lists	list	VERB
admet-698	91	4	the	the	DET
admet-698	91	5	solubility	solubility	NOUN
admet-698	91	6	values	value	NOUN
admet-698	91	7	for	for	ADP
admet-698	91	8	the	the	DET
admet-698	91	9	124	124	NUM
admet-698	91	10	overlapping	overlap	VERB
admet-698	91	11	molecules	molecule	NOUN
admet-698	91	12	measured	measure	VERB
admet-698	91	13	by	by	ADP
admet-698	91	14	the	the	DET
admet-698	91	15	cheqsol	cheqsol	NOUN
admet-698	91	16	and	and	CCONJ
admet-698	91	17	ssf	ssf	NOUN
admet-698	91	18	methods	method	NOUN
admet-698	91	19	.	.	PUNCT
admet-698	92	1	the	the	DET
admet-698	92	2	range	range	NOUN
admet-698	92	3	of	of	ADP
admet-698	92	4	log	log	NOUN
admet-698	92	5	s0	s0	PROPN
admet-698	92	6	spans	span	NOUN
admet-698	92	7	from	from	ADP
admet-698	92	8	-1.0	-1.0	PROPN
admet-698	92	9	to	to	ADP
admet-698	92	10	-10.6	-10.6	PROPN
admet-698	92	11	(	(	PUNCT
admet-698	92	12	log	log	VERB
admet-698	92	13	molar	molar	ADJ
admet-698	92	14	units	unit	NOUN
admet-698	92	15	)	)	PUNCT
admet-698	92	16	,	,	PUNCT
admet-698	92	17	averaging	average	VERB
admet-698	92	18	at	at	ADP
admet-698	92	19	-3.8	-3.8	PROPN
admet-698	92	20	.	.	PUNCT
admet-698	93	1	note	note	NOUN
admet-698	93	2	that	that	SCONJ
admet-698	93	3	indomethacin	indomethacin	PROPN
admet-698	93	4	is	be	AUX
admet-698	93	5	not	not	PART
admet-698	93	6	listed	list	VERB
admet-698	93	7	in	in	ADP
admet-698	93	8	the	the	DET
admet-698	93	9	table	table	NOUN
admet-698	93	10	.	.	PUNCT
admet-698	94	1	the	the	DET
admet-698	94	2	cheqsol	cheqsol	ADJ
admet-698	94	3	value	value	NOUN
admet-698	94	4	was	be	AUX
admet-698	94	5	not	not	PART
admet-698	94	6	accepted	accept	VERB
admet-698	94	7	in	in	ADP
admet-698	94	8	the	the	DET
admet-698	94	9	wiki	wiki	NOUN
admet-698	94	10	-	-	PUNCT
admet-698	94	11	ps0	ps0	ADJ
admet-698	94	12	database	database	NOUN
admet-698	94	13	due	due	ADP
admet-698	94	14	to	to	ADP
admet-698	94	15	the	the	DET
admet-698	94	16	hydrolytic	hydrolytic	ADJ
admet-698	94	17	decomposition	decomposition	NOUN
admet-698	94	18	encountered	encounter	VERB
admet-698	94	19	during	during	ADP
admet-698	94	20	the	the	DET
admet-698	94	21	cheqsol	cheqsol	NOUN
admet-698	94	22	assay	assay	NOUN
admet-698	94	23	[	[	X
admet-698	94	24	30	30	NUM
admet-698	94	25	]	]	PUNCT
admet-698	94	26	.	.	PUNCT
admet-698	95	1	on	on	ADP
admet-698	95	2	the	the	DET
admet-698	95	3	other	other	ADJ
admet-698	95	4	hand	hand	NOUN
admet-698	95	5	,	,	PUNCT
admet-698	95	6	the	the	DET
admet-698	95	7	ph	ph	VERB
admet-698	95	8	-	-	ADJ
admet-698	95	9	metric	metric	ADJ
admet-698	95	10	ddt	ddt	NOUN
admet-698	95	11	method	method	NOUN
admet-698	95	12	indicated	indicate	VERB
admet-698	95	13	log	log	NOUN
admet-698	95	14	s0	s0	PROPN
admet-698	95	15	dtt	dtt	NOUN
admet-698	95	16	=	=	PUNCT
admet-698	95	17	-5.33	-5.33	NUM
admet-698	96	1	[	[	X
admet-698	96	2	31	31	NUM
admet-698	96	3	]	]	PUNCT
admet-698	96	4	,	,	PUNCT
admet-698	96	5	in	in	ADP
admet-698	96	6	good	good	ADJ
admet-698	96	7	agreement	agreement	NOUN
admet-698	96	8	with	with	ADP
admet-698	96	9	the	the	DET
admet-698	96	10	average	average	NOUN
admet-698	96	11	of	of	ADP
admet-698	96	12	20	20	NUM
admet-698	96	13	interlaboratory	interlaboratory	NOUN
admet-698	96	14	ssf	ssf	NOUN
admet-698	96	15	measurements	measurement	NOUN
admet-698	96	16	:	:	PUNCT
admet-698	96	17	log	log	NOUN
admet-698	96	18	s0	s0	PROPN
admet-698	96	19	ssf	ssf	PROPN
admet-698	96	20	=	=	SYM
admet-698	96	21	-5.49	-5.49	NOUN
admet-698	96	22	,	,	PUNCT
admet-698	96	23	sdi	sdi	PROPN
admet-698	96	24	=	=	SYM
admet-698	96	25	0.23	0.23	NUM
admet-698	96	26	.	.	PUNCT
admet-698	97	1	https://pubs.acs.org/doi/%1fsuppl/10.1021/acs.jcim.9b00345	https://pubs.acs.org/doi/%1fsuppl/10.1021/acs.jcim.9b00345	PROPN
admet-698	97	2	https://pubs.acs.org/doi/%1fsuppl/10.1021/acs.jcim.9b00345	https://pubs.acs.org/doi/%1fsuppl/10.1021/acs.jcim.9b00345	PROPN
admet-698	97	3	alex	alex	PROPN
admet-698	97	4	avdeef	avdeef	PROPN
admet-698	97	5	admet	admet	PROPN
admet-698	97	6	&	&	CCONJ
admet-698	97	7	dmpk	dmpk	PROPN
admet-698	97	8	7(3	7(3	NUM
admet-698	97	9	)	)	PUNCT
admet-698	97	10	(	(	PUNCT
admet-698	97	11	2019	2019	NUM
admet-698	97	12	)	)	PUNCT
admet-698	97	13	210	210	NUM
admet-698	97	14	-	-	SYM
admet-698	97	15	219	219	NUM
admet-698	97	16	214	214	NUM
admet-698	97	17	table	table	NOUN
admet-698	97	18	1	1	NUM
admet-698	97	19	.	.	NUM
admet-698	97	20	averaged	average	VERB
admet-698	97	21	saturation	saturation	NOUN
admet-698	97	22	shake	shake	NOUN
admet-698	97	23	-	-	PUNCT
admet-698	97	24	flask	flask	NOUN
admet-698	97	25	(	(	PUNCT
admet-698	97	26	ssf	ssf	NOUN
admet-698	97	27	)	)	PUNCT
admet-698	97	28	and	and	CCONJ
admet-698	97	29	cheqsol	cheqsol	X
admet-698	97	30	(	(	PUNCT
admet-698	97	31	cs	cs	ADJ
admet-698	97	32	)	)	PUNCT
admet-698	97	33	intrinsic	intrinsic	ADJ
admet-698	97	34	solubility	solubility	NOUN
admet-698	97	35	(	(	PUNCT
admet-698	97	36	log	log	NOUN
admet-698	97	37	molar	molar	NOUN
admet-698	97	38	)	)	PUNCT
admet-698	97	39	a	a	DET
admet-698	97	40	compound	compound	NOUN
admet-698	97	41	avg	avg	NOUN
admet-698	97	42	.	.	PROPN
admet-698	98	1	25	25	NUM
admet-698	98	2	°	°	NUM
admet-698	98	3	c	c	NOUN
admet-698	98	4	log	log	NOUN
admet-698	98	5	s0	s0	PROPN
admet-698	98	6	ssf	ssf	PROPN
admet-698	98	7	sd	sd	ADP
admet-698	98	8	ssf	ssf	PROPN
admet-698	98	9	n	n	PROPN
admet-698	98	10	avg	avg	PROPN
admet-698	98	11	.	.	PROPN
admet-698	98	12	25	25	NUM
admet-698	98	13	°	°	NUM
admet-698	98	14	c	c	NOUN
admet-698	98	15	log	log	NOUN
admet-698	98	16	s0	s0	PROPN
admet-698	98	17	cs	cs	PROPN
admet-698	98	18	sd	sd	ADP
admet-698	98	19	cs	cs	PROPN
admet-698	98	20	n	n	PRON
admet-698	98	21	ref	ref	NOUN
admet-698	98	22	.	.	PUNCT
admet-698	99	1	(	(	PUNCT
admet-698	99	2	cheqsol	cheqsol	NOUN
admet-698	99	3	)	)	PUNCT
admet-698	99	4	acebutolol	acebutolol	NOUN
admet-698	99	5	-2.50	-2.50	NUM
admet-698	99	6	0.42	0.42	NUM
admet-698	99	7	2	2	NUM
admet-698	99	8	-2.68	-2.68	NUM
admet-698	99	9	0.31	0.31	NUM
admet-698	99	10	1	1	NUM
admet-698	100	1	[	[	X
admet-698	100	2	17	17	NUM
admet-698	100	3	]	]	PUNCT
admet-698	100	4	acetaminophen	acetaminophen	NOUN
admet-698	100	5	-0.97	-0.97	NOUN
admet-698	100	6	0.10	0.10	NUM
admet-698	100	7	18	18	NUM
admet-698	100	8	-1.03	-1.03	NUM
admet-698	100	9	0.05	0.05	NUM
admet-698	100	10	2	2	NUM
admet-698	100	11	[	[	X
admet-698	100	12	16,22	16,22	NOUN
admet-698	100	13	]	]	X
admet-698	100	14	acetazolamide	acetazolamide	NOUN
admet-698	100	15	-2.38	-2.38	PROPN
admet-698	100	16	0.18	0.18	NUM
admet-698	100	17	10	10	NUM
admet-698	100	18	-2.44	-2.44	NUM
admet-698	100	19	0.04	0.04	NUM
admet-698	100	20	1	1	NUM
admet-698	101	1	[	[	X
admet-698	101	2	16	16	NUM
admet-698	101	3	]	]	X
admet-698	101	4	alprenolol	alprenolol	VERB
admet-698	101	5	-2.83	-2.83	ADV
admet-698	101	6	0.16	0.16	NUM
admet-698	101	7	1	1	NUM
admet-698	101	8	-2.66	-2.66	NUM
admet-698	101	9	0.04	0.04	NUM
admet-698	101	10	2	2	NUM
admet-698	101	11	[	[	X
admet-698	101	12	22,28	22,28	NOUN
admet-698	101	13	]	]	X
admet-698	101	14	amantadine	amantadine	NOUN
admet-698	102	1	-2.76	-2.76	NUM
admet-698	102	2	0.50	0.50	NUM
admet-698	102	3	1	1	NUM
admet-698	102	4	-1.90	-1.90	NUM
admet-698	102	5	0.07	0.07	NUM
admet-698	102	6	2	2	NUM
admet-698	102	7	[	[	X
admet-698	102	8	22,29	22,29	NUM
admet-698	102	9	]	]	X
admet-698	102	10	amiodarone	amiodarone	PROPN
admet-698	102	11	-10.58	-10.58	PROPN
admet-698	102	12	0.35	0.35	NUM
admet-698	102	13	4	4	NUM
admet-698	102	14	-9.68	-9.68	NUM
admet-698	102	15	0.15	0.15	NUM
admet-698	102	16	1	1	NUM
admet-698	102	17	[	[	X
admet-698	102	18	22	22	NUM
admet-698	102	19	]	]	PUNCT
admet-698	102	20	amitriptyline	amitriptyline	NOUN
admet-698	102	21	-4.66	-4.66	NUM
admet-698	102	22	0.40	0.40	NUM
admet-698	102	23	5	5	NUM
admet-698	102	24	-4.55	-4.55	NOUN
admet-698	102	25	0.15	0.15	NUM
admet-698	102	26	1	1	NUM
admet-698	103	1	[	[	X
admet-698	103	2	22	22	NUM
admet-698	103	3	]	]	PUNCT
admet-698	103	4	amodiaquine	amodiaquine	PROPN
admet-698	103	5	-4.74	-4.74	VERB
admet-698	103	6	0.35	0.35	NUM
admet-698	103	7	1	1	NUM
admet-698	103	8	-5.87	-5.87	VERB
admet-698	103	9	0.10	0.10	NUM
admet-698	103	10	2	2	NUM
admet-698	103	11	[	[	X
admet-698	103	12	16,22	16,22	NOUN
admet-698	103	13	]	]	X
admet-698	103	14	amoxicillin	amoxicillin	PROPN
admet-698	103	15	-2.13	-2.13	NUM
admet-698	103	16	0.06	0.06	NUM
admet-698	103	17	10	10	NUM
admet-698	103	18	-1.97	-1.97	NOUN
admet-698	103	19	0.08	0.08	NUM
admet-698	103	20	1	1	NUM
admet-698	103	21	[	[	X
admet-698	103	22	17	17	NUM
admet-698	103	23	]	]	X
admet-698	103	24	aripiprazole	aripiprazole	PROPN
admet-698	103	25	-6.74	-6.74	NOUN
admet-698	103	26	0.16	0.16	NUM
admet-698	103	27	2	2	NUM
admet-698	103	28	-6.43	-6.43	NUM
admet-698	103	29	0.30	0.30	NUM
admet-698	103	30	1	1	NUM
admet-698	103	31	[	[	X
admet-698	103	32	28	28	NUM
admet-698	103	33	]	]	X
admet-698	103	34	atenolol	atenolol	PROPN
admet-698	103	35	-1.20	-1.20	NUM
admet-698	103	36	0.06	0.06	NUM
admet-698	103	37	7	7	NUM
admet-698	103	38	-1.25	-1.25	NUM
admet-698	103	39	0.06	0.06	NUM
admet-698	103	40	4	4	NUM
admet-698	103	41	[	[	X
admet-698	103	42	22,23,27,28	22,23,27,28	NUM
admet-698	103	43	]	]	X
admet-698	103	44	atropine	atropine	NOUN
admet-698	103	45	-2.01	-2.01	NOUN
admet-698	103	46	0.29	0.29	NUM
admet-698	103	47	4	4	NUM
admet-698	103	48	-2.00	-2.00	NUM
admet-698	103	49	0.07	0.07	NUM
admet-698	103	50	1	1	NUM
admet-698	104	1	[	[	X
admet-698	104	2	16	16	NUM
admet-698	104	3	]	]	X
admet-698	104	4	barbital	barbital	NOUN
admet-698	104	5	,	,	PUNCT
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admet-698	104	7	0.15	0.15	NUM
admet-698	104	8	5	5	NUM
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admet-698	104	10	0.07	0.07	NUM
admet-698	104	11	1	1	NUM
admet-698	104	12	[	[	X
admet-698	104	13	16	16	NUM
admet-698	104	14	]	]	X
admet-698	104	15	barbital	barbital	NOUN
admet-698	104	16	,	,	PUNCT
admet-698	104	17	pheno-2.30	pheno-2.30	VERB
admet-698	104	18	0.08	0.08	NUM
admet-698	104	19	25	25	NUM
admet-698	104	20	-2.29	-2.29	NOUN
admet-698	104	21	0.07	0.07	NUM
admet-698	104	22	1	1	NUM
admet-698	105	1	[	[	X
admet-698	105	2	22	22	NUM
admet-698	105	3	]	]	SYM
admet-698	105	4	bendroflumethiazide	bendroflumethiazide	NOUN
admet-698	105	5	-4.35	-4.35	NUM
admet-698	105	6	0.34	0.34	NUM
admet-698	105	7	4	4	NUM
admet-698	105	8	-4.19	-4.19	NUM
admet-698	105	9	0.15	0.15	NUM
admet-698	105	10	2	2	NUM
admet-698	106	1	[	[	X
admet-698	106	2	24,29	24,29	X
admet-698	106	3	]	]	X
admet-698	106	4	benzocaine	benzocaine	NOUN
admet-698	106	5	-2.18	-2.18	NUM
admet-698	106	6	0.12	0.12	NUM
admet-698	106	7	13	13	NUM
admet-698	106	8	-2.33	-2.33	NUM
admet-698	106	9	0.31	0.31	NUM
admet-698	106	10	1	1	NUM
admet-698	107	1	[	[	X
admet-698	107	2	17	17	NUM
admet-698	107	3	]	]	PUNCT
admet-698	107	4	benzoic_acid	benzoic_acid	NOUN
admet-698	107	5	-1.59	-1.59	AUX
admet-698	107	6	0.05	0.05	NUM
admet-698	107	7	12	12	NUM
admet-698	107	8	-1.61	-1.61	NOUN
admet-698	107	9	0.15	0.15	NUM
admet-698	107	10	1	1	NUM
admet-698	107	11	[	[	X
admet-698	107	12	22	22	NUM
admet-698	107	13	]	]	PUNCT
admet-698	107	14	benzoic_acid,4	benzoic_acid,4	NOUN
admet-698	107	15	-	-	PUNCT
admet-698	107	16	hydroxy-1.38	hydroxy-1.38	NOUN
admet-698	107	17	0.10	0.10	NUM
admet-698	107	18	5	5	NUM
admet-698	107	19	-1.46	-1.46	NUM
admet-698	107	20	0.04	0.04	NUM
admet-698	107	21	1	1	NUM
admet-698	108	1	[	[	X
admet-698	108	2	22	22	NUM
admet-698	108	3	]	]	PUNCT
admet-698	108	4	benzthiazide	benzthiazide	ADP
admet-698	108	5	-4.84	-4.84	NUM
admet-698	108	6	0.28	0.28	NUM
admet-698	108	7	4	4	NUM
admet-698	108	8	-4.86	-4.86	NUM
admet-698	108	9	0.04	0.04	NUM
admet-698	108	10	2	2	NUM
admet-698	108	11	[	[	X
admet-698	108	12	22,24	22,24	X
admet-698	108	13	]	]	X
admet-698	108	14	bifonazole	bifonazole	X
admet-698	108	15	-6.27	-6.27	PROPN
admet-698	108	16	0.25	0.25	NUM
admet-698	108	17	4	4	NUM
admet-698	108	18	-6.01	-6.01	NUM
admet-698	108	19	0.15	0.15	NUM
admet-698	108	20	1	1	NUM
admet-698	108	21	[	[	X
admet-698	108	22	25	25	NUM
admet-698	108	23	]	]	PUNCT
admet-698	108	24	bisoprolol	bisoprolol	NOUN
admet-698	108	25	-2.40	-2.40	NUM
admet-698	108	26	0.34	0.34	NUM
admet-698	108	27	2	2	NUM
admet-698	108	28	-1.46	-1.46	NOUN
admet-698	108	29	0.26	0.26	NUM
admet-698	108	30	1	1	NUM
admet-698	109	1	[	[	X
admet-698	109	2	28	28	NUM
admet-698	109	3	]	]	PUNCT
admet-698	109	4	bupivacaine	bupivacaine	NOUN
admet-698	109	5	-3.47	-3.47	NOUN
admet-698	109	6	0.18	0.18	NUM
admet-698	109	7	9	9	NUM
admet-698	109	8	-3.08	-3.08	NUM
admet-698	109	9	0.21	0.21	NUM
admet-698	109	10	2	2	NUM
admet-698	109	11	[	[	X
admet-698	109	12	16,24	16,24	X
admet-698	109	13	]	]	X
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admet-698	109	15	-4.63	-4.63	NUM
admet-698	109	16	0.05	0.05	NUM
admet-698	109	17	1	1	NUM
admet-698	109	18	-4.70	-4.70	NUM
admet-698	109	19	0.22	0.22	NUM
admet-698	109	20	1	1	NUM
admet-698	110	1	[	[	X
admet-698	110	2	22	22	NUM
admet-698	110	3	]	]	X
admet-698	110	4	carvedilol	carvedilol	PROPN
admet-698	110	5	-5.46	-5.46	NUM
admet-698	110	6	0.36	0.36	NUM
admet-698	110	7	12	12	NUM
admet-698	110	8	-4.46	-4.46	NUM
admet-698	110	9	0.27	0.27	NUM
admet-698	110	10	1	1	NUM
admet-698	111	1	[	[	X
admet-698	111	2	28	28	NUM
admet-698	111	3	]	]	X
admet-698	111	4	cephalothin	cephalothin	ADP
admet-698	111	5	-3.40	-3.40	NUM
admet-698	111	6	0.32	0.32	NUM
admet-698	111	7	1	1	NUM
admet-698	111	8	-2.94	-2.94	NUM
admet-698	111	9	0.04	0.04	NUM
admet-698	111	10	1	1	NUM
admet-698	112	1	[	[	X
admet-698	112	2	16	16	NUM
admet-698	112	3	]	]	PUNCT
admet-698	112	4	chlorpheniramine	chlorpheniramine	NOUN
admet-698	112	5	-2.65	-2.65	NUM
admet-698	112	6	0.10	0.10	NUM
admet-698	112	7	1	1	NUM
admet-698	112	8	-2.60	-2.60	NUM
admet-698	112	9	0.12	0.12	NUM
admet-698	112	10	3	3	NUM
admet-698	113	1	[	[	X
admet-698	113	2	21,22	21,22	X
admet-698	113	3	]	]	X
admet-698	113	4	chlorpromazine	chlorpromazine	NOUN
admet-698	113	5	-5.45	-5.45	ADP
admet-698	114	1	0.31	0.31	NUM
admet-698	114	2	11	11	NUM
admet-698	114	3	-5.55	-5.55	NUM
admet-698	114	4	0.04	0.04	NUM
admet-698	114	5	1	1	NUM
admet-698	115	1	[	[	X
admet-698	115	2	22	22	NUM
admet-698	115	3	]	]	PUNCT
admet-698	115	4	chlorpropamide	chlorpropamide	NOUN
admet-698	115	5	-3.15	-3.15	PROPN
admet-698	115	6	0.17	0.17	NUM
admet-698	115	7	5	5	NUM
admet-698	115	8	-3.21	-3.21	NUM
admet-698	115	9	0.05	0.05	NUM
admet-698	115	10	2	2	NUM
admet-698	115	11	[	[	X
admet-698	115	12	16,28	16,28	NUM
admet-698	115	13	]	]	PUNCT
admet-698	115	14	chlorprothixene	chlorprothixene	NOUN
admet-698	115	15	-5.66	-5.66	PRON
admet-698	115	16	0.38	0.38	NUM
admet-698	115	17	3	3	NUM
admet-698	115	18	-6.31	-6.31	NUM
admet-698	115	19	0.44	0.44	NUM
admet-698	115	20	3	3	NUM
admet-698	115	21	[	[	X
admet-698	115	22	16,22	16,22	NOUN
admet-698	115	23	]	]	X
admet-698	115	24	chlorzoxazone	chlorzoxazone	NOUN
admet-698	115	25	-2.78	-2.78	NOUN
admet-698	115	26	0.11	0.11	NUM
admet-698	115	27	3	3	NUM
admet-698	115	28	-2.64	-2.64	NUM
admet-698	115	29	0.04	0.04	NUM
admet-698	115	30	2	2	NUM
admet-698	115	31	[	[	X
admet-698	115	32	16,29	16,29	NUM
admet-698	115	33	]	]	X
admet-698	115	34	cimetidine	cimetidine	NOUN
admet-698	115	35	-1.50	-1.50	NUM
admet-698	115	36	0.22	0.22	NUM
admet-698	115	37	7	7	NUM
admet-698	115	38	-1.69	-1.69	NUM
admet-698	115	39	0.04	0.04	NUM
admet-698	115	40	1	1	NUM
admet-698	116	1	[	[	X
admet-698	116	2	16	16	NUM
admet-698	116	3	]	]	X
admet-698	116	4	ciprofloxacin	ciprofloxacin	NOUN
admet-698	116	5	-3.57	-3.57	NUM
admet-698	116	6	0.19	0.19	NUM
admet-698	116	7	19	19	NUM
admet-698	116	8	-3.60	-3.60	NUM
admet-698	116	9	0.18	0.18	NUM
admet-698	116	10	1	1	NUM
admet-698	116	11	[	[	X
admet-698	116	12	22	22	NUM
admet-698	116	13	]	]	PUNCT
admet-698	116	14	cyproheptadine	cyproheptadine	NOUN
admet-698	116	15	-5.02	-5.02	NUM
admet-698	116	16	0.46	0.46	NUM
admet-698	116	17	4	4	NUM
admet-698	116	18	-5.00	-5.00	NUM
admet-698	116	19	0.15	0.15	NUM
admet-698	116	20	1	1	NUM
admet-698	117	1	[	[	X
admet-698	117	2	24	24	NUM
admet-698	117	3	]	]	PUNCT
admet-698	117	4	diazoxide	diazoxide	NOUN
admet-698	117	5	-3.46	-3.46	NUM
admet-698	117	6	0.26	0.26	NUM
admet-698	117	7	3	3	NUM
admet-698	117	8	-3.36	-3.36	NUM
admet-698	117	9	0.07	0.07	NUM
admet-698	117	10	1	1	NUM
admet-698	117	11	[	[	X
admet-698	117	12	16	16	NUM
admet-698	117	13	]	]	X
admet-698	117	14	dibucaine	dibucaine	NOUN
admet-698	117	15	-3.70	-3.70	NUM
admet-698	117	16	0.35	0.35	NUM
admet-698	117	17	1	1	NUM
admet-698	117	18	-4.20	-4.20	NUM
admet-698	117	19	0.26	0.26	NUM
admet-698	117	20	2	2	NUM
admet-698	117	21	[	[	X
admet-698	117	22	17,24	17,24	NUM
admet-698	117	23	]	]	PUNCT
admet-698	117	24	diclofenac	diclofenac	NOUN
admet-698	117	25	-5.33	-5.33	PROPN
admet-698	117	26	0.19	0.19	NUM
admet-698	117	27	27	27	NUM
admet-698	117	28	-5.40	-5.40	NUM
admet-698	117	29	0.14	0.14	NUM
admet-698	117	30	6	6	NUM
admet-698	117	31	[	[	X
admet-698	117	32	9,21,22,24,26	9,21,22,24,26	NOUN
admet-698	117	33	]	]	PUNCT
admet-698	117	34	diethylstilbestrol	diethylstilbestrol	NOUN
admet-698	117	35	-4.38	-4.38	NOUN
admet-698	117	36	0.38	0.38	NUM
admet-698	117	37	6	6	NUM
admet-698	117	38	-4.43	-4.43	NUM
admet-698	117	39	0.48	0.48	NUM
admet-698	117	40	1	1	NUM
admet-698	118	1	[	[	X
admet-698	118	2	17	17	NUM
admet-698	118	3	]	]	X
admet-698	118	4	difloxacin	difloxacin	PROPN
admet-698	118	5	-3.94	-3.94	NUM
admet-698	118	6	0.10	0.10	NUM
admet-698	118	7	2	2	NUM
admet-698	118	8	-3.60	-3.60	NUM
admet-698	118	9	0.04	0.04	NUM
admet-698	118	10	1	1	NUM
admet-698	119	1	[	[	X
admet-698	119	2	16	16	NUM
admet-698	119	3	]	]	X
admet-698	119	4	diflunisal	diflunisal	NOUN
admet-698	119	5	-5.08	-5.08	PROPN
admet-698	119	6	0.40	0.40	NUM
admet-698	119	7	5	5	NUM
admet-698	119	8	-4.92	-4.92	ADV
admet-698	119	9	0.70	0.70	NUM
admet-698	119	10	6	6	NUM
admet-698	119	11	[	[	X
admet-698	119	12	17,21	17,21	NUM
admet-698	119	13	]	]	X
admet-698	119	14	diltiazem	diltiazem	NOUN
admet-698	119	15	-2.95	-2.95	NUM
admet-698	119	16	0.20	0.20	NUM
admet-698	119	17	1	1	NUM
admet-698	119	18	-3.05	-3.05	NOUN
admet-698	119	19	0.16	0.16	NUM
admet-698	119	20	2	2	NUM
admet-698	119	21	[	[	X
admet-698	119	22	22	22	NUM
admet-698	119	23	]	]	PUNCT
admet-698	119	24	diphenhydramine	diphenhydramine	NOUN
admet-698	119	25	-3.29	-3.29	NUM
admet-698	119	26	0.64	0.64	NUM
admet-698	119	27	3	3	NUM
admet-698	119	28	-2.95	-2.95	NUM
admet-698	119	29	0.04	0.04	NUM
admet-698	119	30	1	1	NUM
admet-698	119	31	[	[	X
admet-698	119	32	22	22	NUM
admet-698	119	33	]	]	X
admet-698	119	34	dipyridamole	dipyridamole	NOUN
admet-698	119	35	-5.13	-5.13	NUM
admet-698	119	36	0.13	0.13	NUM
admet-698	119	37	10	10	NUM
admet-698	119	38	-5.16	-5.16	NUM
admet-698	119	39	0.02	0.02	NUM
admet-698	119	40	1	1	NUM
admet-698	120	1	[	[	X
admet-698	120	2	17	17	NUM
admet-698	120	3	]	]	PUNCT
admet-698	120	4	enrofloxacin	enrofloxacin	PROPN
admet-698	120	5	-3.16	-3.16	NUM
admet-698	120	6	0.13	0.13	NUM
admet-698	120	7	7	7	NUM
admet-698	120	8	-3.18	-3.18	NUM
admet-698	120	9	0.18	0.18	NUM
admet-698	120	10	1	1	NUM
admet-698	120	11	[	[	X
admet-698	120	12	16	16	NUM
admet-698	120	13	]	]	PUNCT
admet-698	120	14	famotidine	famotidine	NOUN
admet-698	120	15	-2.67	-2.67	NUM
admet-698	120	16	0.27	0.27	NUM
admet-698	120	17	5	5	NUM
admet-698	120	18	-2.65	-2.65	NUM
admet-698	120	19	0.04	0.04	NUM
admet-698	120	20	1	1	NUM
admet-698	121	1	[	[	X
admet-698	121	2	22	22	NUM
admet-698	121	3	]	]	X
admet-698	121	4	admet	admet	PROPN
admet-698	121	5	&	&	CCONJ
admet-698	121	6	dmpk	dmpk	PROPN
admet-698	121	7	7(3	7(3	NUM
admet-698	121	8	)	)	PUNCT
admet-698	121	9	(	(	PUNCT
admet-698	121	10	2019	2019	NUM
admet-698	121	11	)	)	PUNCT
admet-698	121	12	210	210	NUM
admet-698	121	13	-	-	SYM
admet-698	121	14	219	219	NUM
admet-698	121	15	multi	multi	ADJ
admet-698	121	16	-	-	ADJ
admet-698	121	17	lab	lab	ADJ
admet-698	121	18	log	log	NOUN
admet-698	121	19	s0	s0	PROPN
admet-698	121	20	measurement	measurement	PROPN
admet-698	121	21	reproducibility	reproducibility	NOUN
admet-698	121	22	in	in	ADP
admet-698	121	23	cheqsol	cheqsol	NOUN
admet-698	121	24	and	and	CCONJ
admet-698	121	25	shake	shake	NOUN
admet-698	121	26	-	-	PUNCT
admet-698	121	27	flask	flask	NOUN
admet-698	121	28	methods	method	NOUN
admet-698	121	29	doi	doi	NOUN
admet-698	121	30	:	:	PUNCT
admet-698	121	31	10.5599	10.5599	NUM
admet-698	121	32	/	/	SYM
admet-698	121	33	admet.698	admet.698	ADJ
admet-698	121	34	215	215	NUM
admet-698	121	35	compound	compound	NOUN
admet-698	121	36	avg	avg	NOUN
admet-698	121	37	.	.	PROPN
admet-698	121	38	25	25	NUM
admet-698	121	39	°	°	NUM
admet-698	121	40	c	c	NOUN
admet-698	121	41	log	log	NOUN
admet-698	121	42	s0	s0	PROPN
admet-698	121	43	ssf	ssf	PROPN
admet-698	121	44	sdssf	sdssf	PROPN
admet-698	121	45	n	n	PROPN
admet-698	121	46	avg	avg	PROPN
admet-698	121	47	.	.	PROPN
admet-698	122	1	25	25	NUM
admet-698	122	2	°	°	NUM
admet-698	122	3	c	c	NOUN
admet-698	122	4	log	log	NOUN
admet-698	122	5	s0	s0	PROPN
admet-698	122	6	cs	cs	PROPN
admet-698	122	7	sdcs	sdcs	PROPN
admet-698	122	8	n	n	DET
admet-698	122	9	ref	ref	NOUN
admet-698	122	10	.	.	PUNCT
admet-698	123	1	(	(	PUNCT
admet-698	123	2	cheqsol	cheqsol	NOUN
admet-698	123	3	)	)	PUNCT
admet-698	123	4	fenoprofen	fenoprofen	NOUN
admet-698	123	5	-3.92	-3.92	NUM
admet-698	123	6	0.20	0.20	NUM
admet-698	123	7	1	1	NUM
admet-698	123	8	-3.70	-3.70	NUM
admet-698	123	9	0.26	0.26	NUM
admet-698	123	10	1	1	NUM
admet-698	124	1	[	[	X
admet-698	124	2	16	16	NUM
admet-698	124	3	]	]	PUNCT
admet-698	124	4	flufenamic_acid	flufenamic_acid	PROPN
admet-698	124	5	-5.27	-5.27	NOUN
admet-698	124	6	0.28	0.28	NUM
admet-698	124	7	10	10	NUM
admet-698	124	8	-5.35	-5.35	NUM
admet-698	124	9	0.04	0.04	NUM
admet-698	124	10	1	1	NUM
admet-698	124	11	[	[	X
admet-698	124	12	22	22	NUM
admet-698	124	13	]	]	PUNCT
admet-698	124	14	flumequine	flumequine	NOUN
admet-698	124	15	-4.10	-4.10	NOUN
admet-698	124	16	0.08	0.08	NUM
admet-698	124	17	1	1	NUM
admet-698	124	18	-3.80	-3.80	NOUN
admet-698	124	19	0.11	0.11	NUM
admet-698	124	20	2	2	NUM
admet-698	124	21	[	[	X
admet-698	124	22	16,22	16,22	NOUN
admet-698	124	23	]	]	PUNCT
admet-698	124	24	flurbiprofen	flurbiprofen	NOUN
admet-698	124	25	-4.36	-4.36	NUM
admet-698	124	26	0.19	0.19	NUM
admet-698	124	27	21	21	NUM
admet-698	124	28	-4.05	-4.05	NOUN
admet-698	124	29	0.15	0.15	NUM
admet-698	124	30	2	2	NUM
admet-698	124	31	[	[	X
admet-698	124	32	16,22	16,22	NOUN
admet-698	124	33	]	]	X
admet-698	124	34	fluvastatin	fluvastatin	NOUN
admet-698	124	35	-3.78	-3.78	NUM
admet-698	124	36	0.06	0.06	NUM
admet-698	124	37	1	1	NUM
admet-698	124	38	-3.87	-3.87	NOUN
admet-698	124	39	0.16	0.16	NUM
admet-698	124	40	1	1	NUM
admet-698	125	1	[	[	X
admet-698	125	2	28	28	NUM
admet-698	125	3	]	]	PUNCT
admet-698	125	4	furosemide	furosemide	VERB
admet-698	125	5	-4.51	-4.51	NUM
admet-698	125	6	0.20	0.20	NUM
admet-698	125	7	19	19	NUM
admet-698	125	8	-4.18	-4.18	NUM
admet-698	125	9	0.12	0.12	NUM
admet-698	125	10	3	3	NUM
admet-698	126	1	[	[	X
admet-698	126	2	21,22	21,22	X
admet-698	126	3	]	]	X
admet-698	126	4	glibenclamide	glibenclamide	NOUN
admet-698	126	5	-6.63	-6.63	PROPN
admet-698	126	6	0.45	0.45	NUM
admet-698	126	7	10	10	NUM
admet-698	126	8	-6.41	-6.41	NOUN
admet-698	126	9	0.07	0.07	NUM
admet-698	126	10	2	2	NUM
admet-698	127	1	[	[	X
admet-698	127	2	27,28	27,28	X
admet-698	127	3	]	]	X
admet-698	127	4	gliclazide	gliclazide	NOUN
admet-698	127	5	-4.27	-4.27	NOUN
admet-698	127	6	0.40	0.40	NUM
admet-698	127	7	14	14	NUM
admet-698	127	8	-4.20	-4.20	NUM
admet-698	127	9	0.15	0.15	NUM
admet-698	127	10	3	3	NUM
admet-698	128	1	[	[	X
admet-698	128	2	23,27,28	23,27,28	NUM
admet-698	128	3	]	]	X
admet-698	128	4	glimepiride	glimepiride	NOUN
admet-698	128	5	-7.22	-7.22	NOUN
admet-698	128	6	0.42	0.42	NUM
admet-698	128	7	5	5	NUM
admet-698	128	8	-6.44	-6.44	NUM
admet-698	128	9	0.15	0.15	NUM
admet-698	128	10	1	1	NUM
admet-698	129	1	[	[	X
admet-698	129	2	27	27	NUM
admet-698	129	3	]	]	SYM
admet-698	129	4	glipizide	glipizide	NOUN
admet-698	129	5	-5.66	-5.66	DET
admet-698	129	6	0.24	0.24	NUM
admet-698	129	7	6	6	NUM
admet-698	129	8	-5.51	-5.51	NUM
admet-698	129	9	0.10	0.10	NUM
admet-698	129	10	3	3	NUM
admet-698	129	11	[	[	X
admet-698	129	12	27	27	NUM
admet-698	129	13	-	-	SYM
admet-698	129	14	29	29	NUM
admet-698	129	15	]	]	PUNCT
admet-698	129	16	guanine	guanine	X
admet-698	129	17	-4.09	-4.09	VERB
admet-698	129	18	0.07	0.07	NUM
admet-698	129	19	2	2	NUM
admet-698	129	20	-4.43	-4.43	NUM
admet-698	129	21	0.37	0.37	NUM
admet-698	129	22	1	1	NUM
admet-698	130	1	[	[	X
admet-698	130	2	16	16	NUM
admet-698	130	3	]	]	AUX
admet-698	130	4	haloperidol	haloperidol	X
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admet-698	130	6	0.14	0.14	NUM
admet-698	130	7	8	8	NUM
admet-698	130	8	-5.52	-5.52	NUM
admet-698	130	9	0.19	0.19	NUM
admet-698	130	10	2	2	NUM
admet-698	130	11	[	[	X
admet-698	130	12	22,24	22,24	X
admet-698	130	13	]	]	X
admet-698	130	14	hydroflumethiazide	hydroflumethiazide	PROPN
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admet-698	130	16	0.11	0.11	NUM
admet-698	130	17	15	15	NUM
admet-698	130	18	-2.70	-2.70	NUM
admet-698	130	19	0.03	0.03	NUM
admet-698	130	20	3	3	NUM
admet-698	130	21	[	[	X
admet-698	130	22	21,29	21,29	NUM
admet-698	130	23	]	]	X
admet-698	130	24	hydrochlorothiazide	hydrochlorothiazide	NOUN
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admet-698	130	26	0.08	0.08	NUM
admet-698	130	27	5	5	NUM
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admet-698	130	29	0.44	0.44	NUM
admet-698	130	30	1	1	NUM
admet-698	130	31	[	[	X
admet-698	130	32	16	16	NUM
admet-698	130	33	]	]	X
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admet-698	130	36	0.22	0.22	NUM
admet-698	130	37	19	19	NUM
admet-698	130	38	-3.97	-3.97	NOUN
admet-698	130	39	0.23	0.23	NUM
admet-698	130	40	4	4	NUM
admet-698	130	41	[	[	SYM
admet-698	130	42	21	21	NUM
admet-698	130	43	-	-	SYM
admet-698	130	44	23	23	NUM
admet-698	130	45	]	]	PUNCT
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admet-698	130	49	7	7	NUM
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admet-698	130	51	0.13	0.13	NUM
admet-698	130	52	4	4	NUM
admet-698	131	1	[	[	SYM
admet-698	131	2	17,21,22	17,21,22	NUM
admet-698	131	3	]	]	X
admet-698	131	4	ketoprofen	ketoprofen	VERB
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admet-698	131	6	0.23	0.23	NUM
admet-698	131	7	20	20	NUM
admet-698	131	8	-3.23	-3.23	NUM
admet-698	131	9	0.02	0.02	NUM
admet-698	131	10	4	4	NUM
admet-698	131	11	[	[	SYM
admet-698	131	12	17,21,24	17,21,24	NUM
admet-698	131	13	]	]	X
admet-698	131	14	lidocaine	lidocaine	NOUN
admet-698	131	15	-1.82	-1.82	NUM
admet-698	131	16	0.08	0.08	NUM
admet-698	131	17	19	19	NUM
admet-698	131	18	-1.87	-1.87	NUM
admet-698	131	19	0.05	0.05	NUM
admet-698	131	20	1	1	NUM
admet-698	132	1	[	[	X
admet-698	132	2	22	22	NUM
admet-698	132	3	]	]	PUNCT
admet-698	132	4	loperamide	loperamide	NOUN
admet-698	132	5	-6.80	-6.80	ADV
admet-698	132	6	0.32	0.32	NUM
admet-698	132	7	3	3	NUM
admet-698	132	8	-7.10	-7.10	NUM
admet-698	132	9	0.04	0.04	NUM
admet-698	132	10	2	2	NUM
admet-698	133	1	[	[	X
admet-698	133	2	16,22	16,22	NOUN
admet-698	133	3	]	]	PUNCT
admet-698	133	4	maprotiline	maprotiline	VERB
admet-698	133	5	-4.54	-4.54	NUM
admet-698	133	6	0.26	0.26	NUM
admet-698	133	7	3	3	NUM
admet-698	133	8	-4.75	-4.75	NUM
admet-698	133	9	0.08	0.08	NUM
admet-698	133	10	2	2	NUM
admet-698	133	11	[	[	X
admet-698	133	12	22,24	22,24	NUM
admet-698	133	13	]	]	X
admet-698	133	14	meclizine	meclizine	NOUN
admet-698	133	15	-5.55	-5.55	NUM
admet-698	133	16	0.66	0.66	NUM
admet-698	133	17	1	1	NUM
admet-698	133	18	-6.48	-6.48	NUM
admet-698	133	19	0.15	0.15	NUM
admet-698	133	20	1	1	NUM
admet-698	134	1	[	[	X
admet-698	134	2	29	29	NUM
admet-698	134	3	]	]	PUNCT
admet-698	134	4	meclofenamic_acid	meclofenamic_acid	VERB
admet-698	134	5	-6.88	-6.88	NUM
admet-698	134	6	0.08	0.08	NUM
admet-698	134	7	2	2	NUM
admet-698	134	8	-6.56	-6.56	NUM
admet-698	134	9	0.42	0.42	NUM
admet-698	134	10	2	2	NUM
admet-698	134	11	[	[	X
admet-698	134	12	17,22	17,22	X
admet-698	134	13	]	]	X
admet-698	134	14	mefenamic_acid	mefenamic_acid	NUM
admet-698	134	15	-6.36	-6.36	NUM
admet-698	134	16	0.42	0.42	NUM
admet-698	134	17	6	6	NUM
admet-698	134	18	-6.54	-6.54	NUM
admet-698	134	19	0.28	0.28	NUM
admet-698	134	20	2	2	NUM
admet-698	134	21	[	[	X
admet-698	134	22	16,22	16,22	NOUN
admet-698	134	23	]	]	X
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admet-698	134	26	0.28	0.28	NUM
admet-698	134	27	1	1	NUM
admet-698	134	28	-3.58	-3.58	NUM
admet-698	134	29	0.07	0.07	NUM
admet-698	134	30	1	1	NUM
admet-698	135	1	[	[	X
admet-698	135	2	29	29	NUM
admet-698	135	3	]	]	X
admet-698	135	4	metoprolol	metoprolol	PROPN
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admet-698	135	6	0.16	0.16	NUM
admet-698	135	7	2	2	NUM
admet-698	135	8	-1.22	-1.22	NOUN
admet-698	135	9	0.01	0.01	NUM
admet-698	135	10	2	2	NUM
admet-698	136	1	[	[	X
admet-698	136	2	22,28	22,28	NOUN
admet-698	136	3	]	]	X
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admet-698	136	5	-1.25	-1.25	PROPN
admet-698	136	6	0.06	0.06	NUM
admet-698	136	7	17	17	NUM
admet-698	136	8	-1.22	-1.22	NOUN
admet-698	136	9	0.04	0.04	NUM
admet-698	136	10	1	1	NUM
admet-698	136	11	[	[	X
admet-698	136	12	16	16	NUM
admet-698	136	13	]	]	PUNCT
admet-698	136	14	miconazole	miconazole	NOUN
admet-698	136	15	-6.04	-6.04	NOUN
admet-698	136	16	0.41	0.41	NUM
admet-698	136	17	4	4	NUM
admet-698	136	18	-5.38	-5.38	NUM
admet-698	136	19	0.45	0.45	NUM
admet-698	136	20	2	2	NUM
admet-698	136	21	[	[	X
admet-698	136	22	16,22	16,22	NOUN
admet-698	136	23	]	]	X
admet-698	136	24	nadolol	nadolol	X
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admet-698	136	26	0.40	0.40	NUM
admet-698	136	27	2	2	NUM
admet-698	136	28	-1.63	-1.63	NUM
admet-698	136	29	0.08	0.08	NUM
admet-698	136	30	2	2	NUM
admet-698	137	1	[	[	X
admet-698	137	2	22,28	22,28	NOUN
admet-698	137	3	]	]	X
admet-698	137	4	nalidixic_acid	nalidixic_acid	PROPN
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admet-698	137	6	0.26	0.26	NUM
admet-698	137	7	8	8	NUM
admet-698	137	8	-3.61	-3.61	NOUN
admet-698	137	9	0.04	0.04	NUM
admet-698	137	10	1	1	NUM
admet-698	138	1	[	[	X
admet-698	138	2	16	16	NUM
admet-698	138	3	]	]	PUNCT
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admet-698	138	5	-	-	PUNCT
admet-698	138	6	3.82	3.82	NUM
admet-698	138	7	0.28	0.28	NUM
admet-698	138	8	5	5	NUM
admet-698	138	9	-3.77	-3.77	NUM
admet-698	138	10	0.15	0.15	NUM
admet-698	138	11	1	1	NUM
admet-698	139	1	[	[	X
admet-698	139	2	22	22	NUM
admet-698	139	3	]	]	PUNCT
admet-698	139	4	naphthol,1	naphthol,1	NOUN
admet-698	139	5	-	-	X
admet-698	139	6	2.09	2.09	NUM
admet-698	139	7	0.10	0.10	NUM
admet-698	139	8	6	6	NUM
admet-698	139	9	-1.98	-1.98	NUM
admet-698	139	10	0.07	0.07	NUM
admet-698	139	11	1	1	NUM
admet-698	140	1	[	[	X
admet-698	140	2	22	22	NUM
admet-698	140	3	]	]	PUNCT
admet-698	140	4	naproxen	naproxen	NOUN
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admet-698	140	6	0.14	0.14	NUM
admet-698	140	7	15	15	NUM
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admet-698	140	9	0.25	0.25	NUM
admet-698	140	10	2	2	NUM
admet-698	141	1	[	[	X
admet-698	141	2	16,22	16,22	NOUN
admet-698	141	3	]	]	X
admet-698	141	4	niflumic_acid	niflumic_acid	X
admet-698	141	5	-4.18	-4.18	NUM
admet-698	141	6	0.13	0.13	NUM
admet-698	141	7	6	6	NUM
admet-698	141	8	-4.11	-4.11	NUM
admet-698	141	9	0.08	0.08	NUM
admet-698	141	10	2	2	NUM
admet-698	141	11	[	[	X
admet-698	141	12	16,22	16,22	NOUN
admet-698	141	13	]	]	X
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admet-698	141	16	0.11	0.11	NUM
admet-698	141	17	11	11	NUM
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admet-698	141	20	2	2	NUM
admet-698	141	21	[	[	X
admet-698	141	22	16,22	16,22	NOUN
admet-698	141	23	]	]	X
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admet-698	141	26	0.16	0.16	NUM
admet-698	141	27	18	18	NUM
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admet-698	141	29	0.15	0.15	NUM
admet-698	141	30	1	1	NUM
admet-698	142	1	[	[	X
admet-698	142	2	22	22	NUM
admet-698	142	3	]	]	PUNCT
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admet-698	142	7	3	3	NUM
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admet-698	142	9	0.02	0.02	NUM
admet-698	142	10	2	2	NUM
admet-698	142	11	[	[	X
admet-698	142	12	16,22	16,22	NOUN
admet-698	142	13	]	]	X
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admet-698	142	16	0.14	0.14	NUM
admet-698	142	17	6	6	NUM
admet-698	142	18	-1.27	-1.27	NUM
admet-698	142	19	0.04	0.04	NUM
admet-698	142	20	1	1	NUM
admet-698	143	1	[	[	X
admet-698	143	2	16	16	NUM
admet-698	143	3	]	]	X
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admet-698	143	6	0.17	0.17	NUM
admet-698	143	7	1	1	NUM
admet-698	143	8	-4.23	-4.23	NUM
admet-698	143	9	0.18	0.18	NUM
admet-698	143	10	1	1	NUM
admet-698	143	11	[	[	X
admet-698	143	12	24	24	NUM
admet-698	143	13	]	]	X
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admet-698	143	16	0.35	0.35	NUM
admet-698	143	17	1	1	NUM
admet-698	143	18	-3.17	-3.17	NUM
admet-698	143	19	0.15	0.15	NUM
admet-698	143	20	1	1	NUM
admet-698	143	21	[	[	X
admet-698	143	22	22	22	NUM
admet-698	143	23	]	]	X
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admet-698	143	27	1	1	NUM
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admet-698	143	29	0.22	0.22	NUM
admet-698	143	30	1	1	NUM
admet-698	143	31	[	[	SYM
admet-698	143	32	28	28	NUM
admet-698	143	33	]	]	PUNCT
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admet-698	143	37	8	8	NUM
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admet-698	143	39	0.24	0.24	NUM
admet-698	143	40	4	4	NUM
admet-698	143	41	[	[	X
admet-698	143	42	16,21,22,24	16,21,22,24	NUM
admet-698	143	43	]	]	X
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admet-698	143	46	0.16	0.16	NUM
admet-698	143	47	6	6	NUM
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admet-698	143	49	0.07	0.07	NUM
admet-698	143	50	1	1	NUM
admet-698	144	1	[	[	X
admet-698	144	2	16	16	NUM
admet-698	144	3	]	]	SYM
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admet-698	144	5	-	-	PUNCT
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admet-698	144	7	0.07	0.07	NUM
admet-698	144	8	1	1	NUM
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admet-698	144	10	0.04	0.04	NUM
admet-698	144	11	1	1	NUM
admet-698	144	12	[	[	X
admet-698	144	13	22	22	NUM
admet-698	144	14	]	]	X
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admet-698	144	17	0.36	0.36	NUM
admet-698	144	18	10	10	NUM
admet-698	144	19	-4.39	-4.39	NUM
admet-698	144	20	0.04	0.04	NUM
admet-698	144	21	1	1	NUM
admet-698	144	22	[	[	X
admet-698	144	23	22	22	NUM
admet-698	144	24	]	]	X
admet-698	144	25	phenytoin	phenytoin	NOUN
admet-698	144	26	-4.08	-4.08	NUM
admet-698	144	27	0.13	0.13	NUM
admet-698	144	28	29	29	NUM
admet-698	144	29	-3.86	-3.86	NUM
admet-698	144	30	0.18	0.18	NUM
admet-698	144	31	1	1	NUM
admet-698	145	1	[	[	X
admet-698	145	2	16	16	NUM
admet-698	145	3	]	]	X
admet-698	145	4	phthalic_acid,2	phthalic_acid,2	NOUN
admet-698	145	5	-	-	PUNCT
admet-698	145	6	1.46	1.46	NUM
admet-698	145	7	0.02	0.02	NUM
admet-698	145	8	10	10	NUM
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admet-698	145	10	0.08	0.08	NUM
admet-698	145	11	2	2	NUM
admet-698	145	12	[	[	X
admet-698	145	13	16,22	16,22	NOUN
admet-698	145	14	]	]	X
admet-698	145	15	alex	alex	PROPN
admet-698	145	16	avdeef	avdeef	PROPN
admet-698	145	17	admet	admet	PROPN
admet-698	145	18	&	&	CCONJ
admet-698	145	19	dmpk	dmpk	PROPN
admet-698	145	20	7(3	7(3	NUM
admet-698	145	21	)	)	PUNCT
admet-698	145	22	(	(	PUNCT
admet-698	145	23	2019	2019	NUM
admet-698	145	24	)	)	PUNCT
admet-698	145	25	210	210	NUM
admet-698	145	26	-	-	SYM
admet-698	145	27	219	219	NUM
admet-698	145	28	216	216	NUM
admet-698	145	29	compound	compound	NOUN
admet-698	145	30	avg	avg	PROPN
admet-698	145	31	.	.	PROPN
admet-698	146	1	25	25	NUM
admet-698	146	2	°	°	NUM
admet-698	146	3	c	c	NOUN
admet-698	146	4	log	log	NOUN
admet-698	146	5	s0	s0	PROPN
admet-698	146	6	ssf	ssf	PROPN
admet-698	146	7	sdssf	sdssf	PROPN
admet-698	146	8	n	n	PROPN
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admet-698	146	10	.	.	PROPN
admet-698	146	11	25	25	NUM
admet-698	146	12	°	°	NUM
admet-698	146	13	c	c	NOUN
admet-698	146	14	log	log	NOUN
admet-698	146	15	s0	s0	PROPN
admet-698	146	16	cs	cs	PROPN
admet-698	146	17	sdcs	sdcs	PROPN
admet-698	146	18	n	n	DET
admet-698	146	19	ref	ref	NOUN
admet-698	146	20	.	.	PUNCT
admet-698	147	1	(	(	PUNCT
admet-698	147	2	cheqsol	cheqsol	NOUN
admet-698	147	3	)	)	PUNCT
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admet-698	147	7	6	6	NUM
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admet-698	147	9	0.13	0.13	NUM
admet-698	147	10	3	3	NUM
admet-698	148	1	[	[	X
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admet-698	148	3	]	]	X
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admet-698	148	6	0.81	0.81	NUM
admet-698	148	7	3	3	NUM
admet-698	148	8	-6.16	-6.16	NUM
admet-698	148	9	0.46	0.46	NUM
admet-698	148	10	1	1	NUM
admet-698	149	1	[	[	X
admet-698	149	2	28	28	NUM
admet-698	149	3	]	]	X
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admet-698	149	6	0.26	0.26	NUM
admet-698	149	7	16	16	NUM
admet-698	149	8	-4.73	-4.73	NUM
admet-698	149	9	0.06	0.06	NUM
admet-698	149	10	4	4	NUM
admet-698	149	11	[	[	X
admet-698	149	12	16,21,22	16,21,22	NUM
admet-698	149	13	]	]	X
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admet-698	149	15	-3.46	-3.46	NUM
admet-698	149	16	0.39	0.39	NUM
admet-698	149	17	1	1	NUM
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admet-698	149	19	0.15	0.15	NUM
admet-698	149	20	1	1	NUM
admet-698	149	21	[	[	X
admet-698	149	22	22	22	NUM
admet-698	149	23	]	]	X
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admet-698	149	26	0.24	0.24	NUM
admet-698	149	27	3	3	NUM
admet-698	149	28	-4.86	-4.86	NUM
admet-698	149	29	0.04	0.04	NUM
admet-698	149	30	1	1	NUM
admet-698	149	31	[	[	X
admet-698	149	32	17	17	NUM
admet-698	149	33	]	]	PUNCT
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admet-698	149	36	0.46	0.46	NUM
admet-698	149	37	2	2	NUM
admet-698	149	38	-1.72	-1.72	NUM
admet-698	149	39	0.07	0.07	NUM
admet-698	149	40	1	1	NUM
admet-698	149	41	[	[	X
admet-698	149	42	22	22	NUM
admet-698	149	43	]	]	PUNCT
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admet-698	149	46	0.26	0.26	NUM
admet-698	149	47	1	1	NUM
admet-698	149	48	-4.75	-4.75	NUM
admet-698	149	49	0.15	0.15	NUM
admet-698	149	50	1	1	NUM
admet-698	150	1	[	[	X
admet-698	150	2	22	22	NUM
admet-698	150	3	]	]	X
admet-698	150	4	promethazine	promethazine	NOUN
admet-698	150	5	-4.39	-4.39	NUM
admet-698	150	6	0.19	0.19	NUM
admet-698	150	7	10	10	NUM
admet-698	150	8	-4.26	-4.26	NUM
admet-698	150	9	0.15	0.15	NUM
admet-698	150	10	1	1	NUM
admet-698	151	1	[	[	X
admet-698	151	2	22	22	NUM
admet-698	151	3	]	]	PUNCT
admet-698	151	4	propranolol	propranolol	X
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admet-698	151	6	0.30	0.30	NUM
admet-698	151	7	4	4	NUM
admet-698	151	8	-3.49	-3.49	NUM
admet-698	151	9	0.06	0.06	NUM
admet-698	151	10	6	6	NUM
admet-698	151	11	[	[	SYM
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admet-698	151	13	-	-	SYM
admet-698	151	14	24,27,28	24,27,28	NUM
admet-698	151	15	]	]	PUNCT
admet-698	151	16	pyrimethamine	pyrimethamine	NOUN
admet-698	151	17	-3.96	-3.96	NUM
admet-698	151	18	0.57	0.57	NUM
admet-698	151	19	3	3	NUM
admet-698	151	20	-4.11	-4.11	NOUN
admet-698	151	21	0.22	0.22	NUM
admet-698	151	22	1	1	NUM
admet-698	152	1	[	[	X
admet-698	152	2	22	22	NUM
admet-698	152	3	]	]	PUNCT
admet-698	152	4	quinine	quinine	PROPN
admet-698	152	5	-3.16	-3.16	NOUN
admet-698	152	6	0.67	0.67	NUM
admet-698	152	7	5	5	NUM
admet-698	152	8	-2.80	-2.80	NUM
admet-698	152	9	0.01	0.01	NUM
admet-698	152	10	2	2	NUM
admet-698	153	1	[	[	X
admet-698	153	2	16,22	16,22	NOUN
admet-698	153	3	]	]	X
admet-698	153	4	ranitidine	ranitidine	NOUN
admet-698	153	5	-1.70	-1.70	NUM
admet-698	153	6	0.57	0.57	NUM
admet-698	153	7	1	1	NUM
admet-698	153	8	-2.50	-2.50	NUM
admet-698	153	9	0.26	0.26	NUM
admet-698	153	10	1	1	NUM
admet-698	154	1	[	[	X
admet-698	154	2	16	16	NUM
admet-698	154	3	]	]	PUNCT
admet-698	154	4	rosiglitazone	rosiglitazone	NOUN
admet-698	154	5	-5.28	-5.28	NOUN
admet-698	154	6	0.50	0.50	NUM
admet-698	154	7	3	3	NUM
admet-698	154	8	-5.22	-5.22	NUM
admet-698	154	9	0.61	0.61	NUM
admet-698	154	10	1	1	NUM
admet-698	155	1	[	[	X
admet-698	155	2	28	28	NUM
admet-698	155	3	]	]	X
admet-698	155	4	salicylic_acid	salicylic_acid	NOUN
admet-698	155	5	-1.88	-1.88	NUM
admet-698	155	6	0.08	0.08	NUM
admet-698	155	7	20	20	NUM
admet-698	155	8	-1.93	-1.93	NUM
admet-698	155	9	0.04	0.04	NUM
admet-698	155	10	1	1	NUM
admet-698	155	11	[	[	X
admet-698	155	12	17	17	NUM
admet-698	155	13	]	]	PUNCT
admet-698	155	14	sertraline	sertraline	NOUN
admet-698	155	15	-5.41	-5.41	NOUN
admet-698	155	16	0.28	0.28	NUM
admet-698	155	17	2	2	NUM
admet-698	155	18	-4.83	-4.83	NUM
admet-698	155	19	0.15	0.15	NUM
admet-698	155	20	1	1	NUM
admet-698	156	1	[	[	X
admet-698	156	2	22	22	NUM
admet-698	156	3	]	]	PUNCT
admet-698	156	4	sulfacetamide	sulfacetamide	PROPN
admet-698	156	5	-1.50	-1.50	PROPN
admet-698	156	6	0.05	0.05	NUM
admet-698	156	7	5	5	NUM
admet-698	156	8	-1.52	-1.52	NUM
admet-698	156	9	0.04	0.04	NUM
admet-698	156	10	1	1	NUM
admet-698	157	1	[	[	X
admet-698	157	2	16	16	NUM
admet-698	157	3	]	]	PUNCT
admet-698	157	4	sulfamerazine	sulfamerazine	NOUN
admet-698	157	5	-3.10	-3.10	NOUN
admet-698	157	6	0.07	0.07	NUM
admet-698	157	7	6	6	NUM
admet-698	157	8	-3.12	-3.12	NUM
admet-698	157	9	0.05	0.05	NUM
admet-698	157	10	1	1	NUM
admet-698	157	11	[	[	X
admet-698	157	12	22	22	NUM
admet-698	157	13	]	]	PUNCT
admet-698	157	14	sulfamethazine	sulfamethazine	NOUN
admet-698	157	15	-2.63	-2.63	NOUN
admet-698	157	16	0.27	0.27	NUM
admet-698	157	17	6	6	NUM
admet-698	157	18	-2.73	-2.73	NUM
admet-698	157	19	0.04	0.04	NUM
admet-698	157	20	1	1	NUM
admet-698	157	21	[	[	X
admet-698	157	22	16	16	NUM
admet-698	157	23	]	]	PUNCT
admet-698	157	24	sulfamethizole	sulfamethizole	NOUN
admet-698	157	25	-2.77	-2.77	NUM
admet-698	157	26	0.14	0.14	NUM
admet-698	157	27	5	5	NUM
admet-698	157	28	-2.78	-2.78	NOUN
admet-698	157	29	0.14	0.14	NUM
admet-698	157	30	1	1	NUM
admet-698	157	31	[	[	X
admet-698	157	32	17	17	NUM
admet-698	157	33	]	]	PUNCT
admet-698	157	34	sulfasalazine	sulfasalazine	NOUN
admet-698	157	35	-6.47	-6.47	NUM
admet-698	157	36	0.08	0.08	NUM
admet-698	157	37	7	7	NUM
admet-698	157	38	-6.21	-6.21	NUM
admet-698	157	39	0.10	0.10	NUM
admet-698	157	40	2	2	NUM
admet-698	157	41	[	[	X
admet-698	157	42	16,22	16,22	NOUN
admet-698	157	43	]	]	X
admet-698	157	44	sulfathiazole	sulfathiazole	NOUN
admet-698	157	45	-2.61	-2.61	NOUN
admet-698	157	46	0.23	0.23	NUM
admet-698	157	47	8	8	NUM
admet-698	157	48	-2.69	-2.69	NUM
admet-698	157	49	0.15	0.15	NUM
admet-698	157	50	1	1	NUM
admet-698	157	51	[	[	X
admet-698	157	52	22	22	NUM
admet-698	157	53	]	]	X
admet-698	157	54	terfenadine	terfenadine	NOUN
admet-698	157	55	-7.68	-7.68	NUM
admet-698	157	56	0.71	0.71	NUM
admet-698	157	57	10	10	NUM
admet-698	157	58	-8.40	-8.40	NUM
admet-698	157	59	0.15	0.15	NUM
admet-698	157	60	1	1	NUM
admet-698	157	61	[	[	X
admet-698	157	62	29	29	NUM
admet-698	157	63	]	]	SYM
admet-698	157	64	tetracaine	tetracaine	NOUN
admet-698	157	65	-3.22	-3.22	NUM
admet-698	157	66	0.11	0.11	NUM
admet-698	157	67	1	1	NUM
admet-698	157	68	-3.05	-3.05	NUM
admet-698	157	69	0.06	0.06	NUM
admet-698	157	70	2	2	NUM
admet-698	157	71	[	[	X
admet-698	157	72	16,24	16,24	X
admet-698	157	73	]	]	PUNCT
admet-698	157	74	tetracycline	tetracycline	PROPN
admet-698	157	75	-3.29	-3.29	PROPN
admet-698	157	76	0.05	0.05	NUM
admet-698	157	77	6	6	NUM
admet-698	157	78	-3.00	-3.00	NUM
admet-698	157	79	0.09	0.09	NUM
admet-698	157	80	2	2	NUM
admet-698	157	81	[	[	X
admet-698	157	82	16,29	16,29	NUM
admet-698	157	83	]	]	X
admet-698	157	84	tetracycline	tetracycline	NOUN
admet-698	157	85	,	,	PUNCT
admet-698	157	86	oxy-3.27	oxy-3.27	PROPN
admet-698	157	87	0.07	0.07	NUM
admet-698	157	88	4	4	NUM
admet-698	157	89	-3.09	-3.09	NUM
admet-698	157	90	0.33	0.33	NUM
admet-698	157	91	1	1	NUM
admet-698	157	92	[	[	X
admet-698	157	93	16	16	NUM
admet-698	157	94	]	]	PUNCT
admet-698	157	95	thiabendazole	thiabendazole	NOUN
admet-698	157	96	-4.13	-4.13	NUM
admet-698	157	97	0.46	0.46	NUM
admet-698	157	98	3	3	NUM
admet-698	157	99	-3.48	-3.48	NUM
admet-698	157	100	0.10	0.10	NUM
admet-698	157	101	1	1	NUM
admet-698	157	102	[	[	X
admet-698	157	103	17	17	NUM
admet-698	157	104	]	]	PUNCT
admet-698	157	105	thymol	thymol	NOUN
admet-698	157	106	-2.18	-2.18	NUM
admet-698	157	107	0.05	0.05	NUM
admet-698	157	108	3	3	NUM
admet-698	157	109	-2.19	-2.19	NUM
admet-698	157	110	0.04	0.04	NUM
admet-698	157	111	1	1	NUM
admet-698	157	112	[	[	X
admet-698	157	113	22	22	NUM
admet-698	157	114	]	]	SYM
admet-698	157	115	tolbutamide	tolbutamide	NOUN
admet-698	157	116	-3.55	-3.55	NUM
admet-698	157	117	0.11	0.11	NUM
admet-698	157	118	5	5	NUM
admet-698	157	119	-3.50	-3.50	NOUN
admet-698	157	120	0.05	0.05	NUM
admet-698	157	121	2	2	NUM
admet-698	158	1	[	[	X
admet-698	158	2	17,28	17,28	NOUN
admet-698	158	3	]	]	X
admet-698	158	4	tolmetin	tolmetin	NOUN
admet-698	158	5	-4.05	-4.05	VERB
admet-698	158	6	0.15	0.15	NUM
admet-698	158	7	1	1	NUM
admet-698	158	8	-4.11	-4.11	NUM
admet-698	158	9	0.03	0.03	NUM
admet-698	158	10	2	2	NUM
admet-698	158	11	[	[	X
admet-698	158	12	16,22	16,22	NOUN
admet-698	158	13	]	]	X
admet-698	158	14	trazodone	trazodone	PROPN
admet-698	158	15	-3.31	-3.31	X
admet-698	158	16	0.09	0.09	NUM
admet-698	158	17	4	4	NUM
admet-698	158	18	-3.19	-3.19	NUM
admet-698	158	19	0.40	0.40	NUM
admet-698	158	20	2	2	NUM
admet-698	158	21	[	[	X
admet-698	158	22	17	17	NUM
admet-698	158	23	]	]	X
admet-698	158	24	trichlormethiazide	trichlormethiazide	NOUN
admet-698	158	25	-3.64	-3.64	NUM
admet-698	158	26	0.12	0.12	NUM
admet-698	158	27	3	3	NUM
admet-698	158	28	-3.38	-3.38	NUM
admet-698	158	29	0.18	0.18	NUM
admet-698	158	30	3	3	NUM
admet-698	158	31	[	[	X
admet-698	158	32	16,22	16,22	NOUN
admet-698	158	33	]	]	X
admet-698	158	34	trimethoprim	trimethoprim	NOUN
admet-698	158	35	-2.64	-2.64	NUM
admet-698	158	36	0.39	0.39	NUM
admet-698	158	37	9	9	NUM
admet-698	158	38	-2.95	-2.95	NUM
admet-698	158	39	0.15	0.15	NUM
admet-698	158	40	1	1	NUM
admet-698	159	1	[	[	X
admet-698	159	2	16	16	NUM
admet-698	159	3	]	]	PUNCT
admet-698	159	4	verapamil	verapamil	NOUN
admet-698	159	5	-4.36	-4.36	NUM
admet-698	159	6	0.28	0.28	NUM
admet-698	159	7	9	9	NUM
admet-698	159	8	-4.07	-4.07	NUM
admet-698	159	9	0.22	0.22	NUM
admet-698	159	10	3	3	NUM
admet-698	159	11	[	[	X
admet-698	159	12	21,22	21,22	X
admet-698	159	13	]	]	X
admet-698	159	14	warfarin	warfarin	NOUN
admet-698	159	15	-4.77	-4.77	NUM
admet-698	159	16	0.22	0.22	NUM
admet-698	159	17	9	9	NUM
admet-698	159	18	-4.80	-4.80	NUM
admet-698	159	19	0.14	0.14	NUM
admet-698	159	20	2	2	NUM
admet-698	160	1	[	[	X
admet-698	160	2	22,24	22,24	X
admet-698	160	3	]	]	X
admet-698	160	4	a	a	DET
admet-698	160	5	sd	sd	NOUN
admet-698	160	6	refers	refer	VERB
admet-698	160	7	to	to	ADP
admet-698	160	8	the	the	DET
admet-698	160	9	standard	standard	ADJ
admet-698	160	10	deviation	deviation	NOUN
admet-698	160	11	of	of	ADP
admet-698	160	12	reported	report	VERB
admet-698	160	13	values	value	NOUN
admet-698	160	14	from	from	ADP
admet-698	160	15	n	n	CCONJ
admet-698	160	16	different	different	ADJ
admet-698	160	17	sourcs	sourc	NOUN
admet-698	160	18	.	.	PUNCT
admet-698	161	1	the	the	DET
admet-698	161	2	average	average	ADJ
admet-698	161	3	interlaboratory	interlaboratory	ADJ
admet-698	161	4	sdi	sdi	PROPN
admet-698	161	5	values	value	NOUN
admet-698	161	6	for	for	ADP
admet-698	161	7	for	for	ADP
admet-698	161	8	the	the	DET
admet-698	161	9	two	two	NUM
admet-698	161	10	sets	set	NOUN
admet-698	161	11	of	of	ADP
admet-698	161	12	data	datum	NOUN
admet-698	161	13	are	be	AUX
admet-698	161	14	:	:	PUNCT
admet-698	161	15	sdi	sdi	PROPN
admet-698	161	16	ssf	ssf	NOUN
admet-698	161	17	=	=	PROPN
admet-698	161	18	0.24	0.24	NUM
admet-698	161	19	and	and	CCONJ
admet-698	161	20	sdi	sdi	PROPN
admet-698	161	21	cs	cs	X
admet-698	161	22	=	=	SYM
admet-698	161	23	0.15	0.15	NUM
admet-698	161	24	log	log	NOUN
admet-698	161	25	unit	unit	NOUN
admet-698	161	26	.	.	PUNCT
admet-698	162	1	figure	figure	NOUN
admet-698	162	2	1	1	NUM
admet-698	162	3	shows	show	VERB
admet-698	162	4	the	the	DET
admet-698	162	5	correlation	correlation	NOUN
admet-698	162	6	plot	plot	NOUN
admet-698	162	7	between	between	ADP
admet-698	162	8	the	the	DET
admet-698	162	9	two	two	NUM
admet-698	162	10	types	type	NOUN
admet-698	162	11	of	of	ADP
admet-698	162	12	measurements	measurement	NOUN
admet-698	162	13	,	,	PUNCT
admet-698	162	14	with	with	ADP
admet-698	162	15	each	each	DET
admet-698	162	16	point	point	NOUN
admet-698	162	17	showing	show	VERB
admet-698	162	18	both	both	DET
admet-698	162	19	method	method	NOUN
admet-698	162	20	interlaboratory	interlaboratory	ADJ
admet-698	162	21	error	error	NOUN
admet-698	162	22	bars	bar	NOUN
admet-698	162	23	.	.	PUNCT
admet-698	163	1	the	the	DET
admet-698	163	2	statistics	statistic	NOUN
admet-698	163	3	have	have	AUX
admet-698	163	4	improved	improve	VERB
admet-698	163	5	slightly	slightly	ADV
admet-698	163	6	over	over	ADP
admet-698	163	7	the	the	DET
admet-698	163	8	2015	2015	NUM
admet-698	163	9	comparison	comparison	NOUN
admet-698	163	10	[	[	X
admet-698	163	11	19	19	NUM
admet-698	163	12	]	]	PUNCT
admet-698	163	13	,	,	PUNCT
admet-698	163	14	with	with	ADP
admet-698	163	15	current	current	ADJ
admet-698	163	16	values	value	NOUN
admet-698	163	17	being	be	AUX
admet-698	163	18	r2	r2	PROPN
admet-698	163	19	=	=	SYM
admet-698	163	20	0.96	0.96	NUM
admet-698	163	21	,	,	PUNCT
admet-698	163	22	rmse	rmse	NOUN
admet-698	163	23	=	=	SYM
admet-698	163	24	0.34	0.34	NUM
admet-698	163	25	log	log	NOUN
admet-698	163	26	unit	unit	NOUN
admet-698	163	27	,	,	PUNCT
admet-698	163	28	with	with	ADP
admet-698	163	29	a	a	DET
admet-698	163	30	lower	low	ADJ
admet-698	163	31	slight	slight	ADJ
admet-698	163	32	bias	bias	NOUN
admet-698	163	33	of	of	ADP
admet-698	163	34	-0.07	-0.07	NUM
admet-698	163	35	log	log	PROPN
admet-698	163	36	unit	unit	NOUN
admet-698	163	37	.	.	PUNCT
admet-698	164	1	the	the	DET
admet-698	164	2	average	average	ADJ
admet-698	164	3	interlaboratory	interlaboratory	ADJ
admet-698	164	4	standard	standard	ADJ
admet-698	164	5	deviation	deviation	NOUN
admet-698	164	6	is	be	AUX
admet-698	164	7	slightly	slightly	ADV
admet-698	164	8	lower	low	ADJ
admet-698	164	9	for	for	ADP
admet-698	164	10	the	the	DET
admet-698	164	11	cheqsol	cheqsol	NOUN
admet-698	164	12	set	set	VERB
admet-698	164	13	over	over	ADP
admet-698	164	14	that	that	PRON
admet-698	164	15	of	of	ADP
admet-698	164	16	the	the	DET
admet-698	164	17	ssf	ssf	NOUN
admet-698	164	18	set	set	VERB
admet-698	164	19	:	:	PUNCT
admet-698	164	20	sdi	sdi	PROPN
admet-698	164	21	cs	cs	X
admet-698	164	22	=	=	PUNCT
admet-698	164	23	0.15	0.15	NUM
admet-698	164	24	and	and	CCONJ
admet-698	164	25	sdi	sdi	PROPN
admet-698	164	26	ssf	ssf	NOUN
admet-698	164	27	=	=	PROPN
admet-698	164	28	0.24	0.24	NUM
admet-698	164	29	,	,	PUNCT
admet-698	164	30	which	which	PRON
admet-698	164	31	probably	probably	ADV
admet-698	164	32	highlights	highlight	VERB
admet-698	164	33	the	the	DET
admet-698	164	34	benefit	benefit	NOUN
admet-698	164	35	of	of	ADP
admet-698	164	36	using	use	VERB
admet-698	164	37	a	a	DET
admet-698	164	38	highly	highly	ADV
admet-698	164	39	standardized	standardized	ADJ
admet-698	164	40	method	method	NOUN
admet-698	164	41	(	(	PUNCT
admet-698	164	42	cheqsol	cheqsol	NOUN
admet-698	164	43	)	)	PUNCT
admet-698	164	44	over	over	ADP
admet-698	164	45	an	an	DET
admet-698	164	46	‘	'	PUNCT
admet-698	164	47	open	open	ADJ
admet-698	164	48	’	'	PUNCT
admet-698	164	49	method	method	NOUN
admet-698	164	50	(	(	PUNCT
admet-698	164	51	ssf	ssf	NOUN
admet-698	164	52	)	)	PUNCT
admet-698	164	53	.	.	PUNCT
admet-698	165	1	it	it	PRON
admet-698	165	2	should	should	AUX
admet-698	165	3	be	be	AUX
admet-698	165	4	kept	keep	VERB
admet-698	165	5	in	in	ADP
admet-698	165	6	mind	mind	NOUN
admet-698	165	7	that	that	SCONJ
admet-698	165	8	the	the	DET
admet-698	165	9	above	above	ADJ
admet-698	165	10	comparison	comparison	NOUN
admet-698	165	11	sets	set	NOUN
admet-698	165	12	are	be	AUX
admet-698	165	13	small	small	ADJ
admet-698	165	14	.	.	PUNCT
admet-698	166	1	for	for	ADP
admet-698	166	2	870	870	NUM
admet-698	166	3	of	of	ADP
admet-698	166	4	these	these	DET
admet-698	166	5	sorts	sort	NOUN
admet-698	166	6	of	of	ADP
admet-698	166	7	comparisons	comparison	NOUN
admet-698	166	8	,	,	PUNCT
admet-698	166	9	sdi	sdi	PROPN
admet-698	166	10	all	all	PRON
admet-698	166	11	=	=	SYM
admet-698	166	12	0.17	0.17	NUM
admet-698	166	13	.	.	PUNCT
admet-698	167	1	the	the	DET
admet-698	167	2	intralaboratory	intralaboratory	ADJ
admet-698	167	3	comparison	comparison	NOUN
admet-698	167	4	between	between	ADP
admet-698	167	5	the	the	DET
admet-698	167	6	methods	method	NOUN
admet-698	167	7	by	by	ADP
admet-698	167	8	one	one	NUM
admet-698	167	9	group	group	NOUN
admet-698	167	10	of	of	ADP
admet-698	167	11	researchers	researcher	NOUN
admet-698	167	12	performing	perform	VERB
admet-698	167	13	both	both	CCONJ
admet-698	167	14	the	the	DET
admet-698	167	15	ssf	ssf	NOUN
admet-698	167	16	and	and	CCONJ
admet-698	167	17	cheqsol	cheqsol	ADJ
admet-698	167	18	measurements	measurement	NOUN
admet-698	167	19	(	(	PUNCT
admet-698	167	20	both	both	PRON
admet-698	167	21	highlystandardized	highlystandardize	VERB
admet-698	167	22	)	)	PUNCT
admet-698	168	1	[	[	X
admet-698	168	2	32	32	NUM
admet-698	168	3	]	]	PUNCT
admet-698	168	4	produced	produce	VERB
admet-698	168	5	the	the	DET
admet-698	168	6	statistics	statistic	NOUN
admet-698	168	7	r2	r2	PROPN
admet-698	168	8	=	=	SYM
admet-698	168	9	0.96	0.96	NUM
admet-698	168	10	,	,	PUNCT
admet-698	168	11	rmse	rmse	NOUN
admet-698	169	1	=	=	NOUN
admet-698	169	2	0.20	0.20	NUM
admet-698	169	3	for	for	ADP
admet-698	169	4	15	15	NUM
admet-698	169	5	compounds	compound	NOUN
admet-698	169	6	,	,	PUNCT
admet-698	169	7	comparable	comparable	ADJ
admet-698	169	8	to	to	ADP
admet-698	169	9	sdi	sdi	PROPN
admet-698	169	10	all	all	PRON
admet-698	169	11	.	.	PUNCT
admet-698	170	1	admet	admet	PROPN
admet-698	170	2	&	&	CCONJ
admet-698	170	3	dmpk	dmpk	PROPN
admet-698	170	4	7(3	7(3	NUM
admet-698	170	5	)	)	PUNCT
admet-698	170	6	(	(	PUNCT
admet-698	170	7	2019	2019	NUM
admet-698	170	8	)	)	PUNCT
admet-698	170	9	210	210	NUM
admet-698	170	10	-	-	SYM
admet-698	170	11	219	219	NUM
admet-698	170	12	multi	multi	ADJ
admet-698	170	13	-	-	ADJ
admet-698	170	14	lab	lab	ADJ
admet-698	170	15	log	log	NOUN
admet-698	170	16	s0	s0	PROPN
admet-698	170	17	measurement	measurement	PROPN
admet-698	170	18	reproducibility	reproducibility	NOUN
admet-698	170	19	in	in	ADP
admet-698	170	20	cheqsol	cheqsol	NOUN
admet-698	170	21	and	and	CCONJ
admet-698	170	22	shake	shake	NOUN
admet-698	170	23	-	-	PUNCT
admet-698	170	24	flask	flask	NOUN
admet-698	170	25	methods	method	NOUN
admet-698	170	26	doi	doi	NOUN
admet-698	170	27	:	:	PUNCT
admet-698	170	28	10.5599	10.5599	NUM
admet-698	170	29	/	/	SYM
admet-698	170	30	admet.698	admet.698	NOUN
admet-698	170	31	217	217	NUM
admet-698	170	32	the	the	DET
admet-698	170	33	latter	latter	ADJ
admet-698	170	34	is	be	AUX
admet-698	170	35	the	the	DET
admet-698	170	36	target	target	NOUN
admet-698	170	37	for	for	ADP
admet-698	170	38	computational	computational	ADJ
admet-698	170	39	methods	method	NOUN
admet-698	170	40	to	to	PART
admet-698	170	41	aim	aim	VERB
admet-698	170	42	at	at	ADP
admet-698	170	43	,	,	PUNCT
admet-698	170	44	provided	provide	VERB
admet-698	170	45	that	that	SCONJ
admet-698	170	46	the	the	DET
admet-698	170	47	training	training	NOUN
admet-698	170	48	sets	set	NOUN
admet-698	170	49	are	be	AUX
admet-698	170	50	of	of	ADP
admet-698	170	51	high	high	ADJ
admet-698	170	52	and	and	CCONJ
admet-698	170	53	consistent	consistent	ADJ
admet-698	170	54	quality	quality	NOUN
admet-698	170	55	.	.	PUNCT
admet-698	171	1	figure	figure	NOUN
admet-698	171	2	1	1	NUM
admet-698	171	3	.	.	PUNCT
admet-698	172	1	the	the	DET
admet-698	172	2	correlation	correlation	NOUN
admet-698	172	3	plot	plot	NOUN
admet-698	172	4	between	between	ADP
admet-698	172	5	published	publish	VERB
admet-698	172	6	cheqsol	cheqsol	NOUN
admet-698	172	7	and	and	CCONJ
admet-698	172	8	saturation	saturation	NOUN
admet-698	172	9	shake	shake	NOUN
admet-698	172	10	-	-	PUNCT
admet-698	172	11	flask	flask	NOUN
admet-698	172	12	(	(	PUNCT
admet-698	172	13	ssf	ssf	NOUN
admet-698	172	14	)	)	PUNCT
admet-698	172	15	intrinsic	intrinsic	ADJ
admet-698	172	16	solubility	solubility	NOUN
admet-698	172	17	values	value	NOUN
admet-698	172	18	(	(	PUNCT
admet-698	172	19	log	log	NOUN
admet-698	172	20	molar	molar	NOUN
admet-698	172	21	)	)	PUNCT
admet-698	172	22	at	at	ADP
admet-698	172	23	25	25	NUM
admet-698	172	24	°	°	NOUN
admet-698	172	25	c	c	NOUN
admet-698	172	26	.	.	PUNCT
admet-698	173	1	the	the	DET
admet-698	173	2	solid	solid	ADJ
admet-698	173	3	diagonal	diagonal	ADJ
admet-698	173	4	line	line	NOUN
admet-698	173	5	is	be	AUX
admet-698	173	6	the	the	DET
admet-698	173	7	identity	identity	NOUN
admet-698	173	8	line	line	NOUN
admet-698	173	9	.	.	PUNCT
admet-698	174	1	the	the	DET
admet-698	174	2	dashed	dash	VERB
admet-698	174	3	lines	line	NOUN
admet-698	174	4	are	be	AUX
admet-698	174	5	displacements	displacement	NOUN
admet-698	174	6	by	by	ADP
admet-698	174	7	±0.5	±0.5	PROPN
admet-698	174	8	log	log	NOUN
admet-698	174	9	.	.	PUNCT
admet-698	175	1	conclusions	conclusion	NOUN
admet-698	175	2	this	this	DET
admet-698	175	3	brief	brief	ADJ
admet-698	175	4	commentary	commentary	NOUN
admet-698	175	5	reasserts	reassert	VERB
admet-698	175	6	that	that	SCONJ
admet-698	175	7	the	the	DET
admet-698	175	8	quality	quality	NOUN
admet-698	175	9	of	of	ADP
admet-698	175	10	the	the	DET
admet-698	175	11	standardized	standardized	ADJ
admet-698	175	12	cheqsol	cheqsol	NOUN
admet-698	175	13	measurements	measurement	NOUN
admet-698	175	14	is	be	AUX
admet-698	175	15	comparable	comparable	ADJ
admet-698	175	16	to	to	ADP
admet-698	175	17	that	that	PRON
admet-698	175	18	of	of	ADP
admet-698	175	19	the	the	DET
admet-698	175	20	‘	'	PUNCT
admet-698	175	21	gold	gold	ADJ
admet-698	175	22	standard	standard	NOUN
admet-698	175	23	’	'	PUNCT
admet-698	175	24	saturation	saturation	NOUN
admet-698	175	25	shake	shake	NOUN
admet-698	175	26	-	-	PUNCT
admet-698	175	27	flask	flask	NOUN
admet-698	175	28	measurements	measurement	NOUN
admet-698	175	29	.	.	PUNCT
admet-698	176	1	measurement	measurement	NOUN
admet-698	176	2	errors	error	NOUN
admet-698	176	3	are	be	AUX
admet-698	176	4	much	much	ADV
admet-698	176	5	lower	low	ADJ
admet-698	176	6	than	than	ADP
admet-698	176	7	commonly	commonly	ADV
admet-698	176	8	acknowledged	acknowledge	VERB
admet-698	176	9	in	in	ADP
admet-698	176	10	the	the	DET
admet-698	176	11	computational	computational	ADJ
admet-698	176	12	prediction	prediction	NOUN
admet-698	176	13	community	community	NOUN
admet-698	176	14	.	.	PUNCT
admet-698	177	1	the	the	DET
admet-698	177	2	intralaboratory	intralaboratory	NOUN
admet-698	177	3	(	(	PUNCT
admet-698	177	4	single	single	ADJ
admet-698	177	5	instrument	instrument	NOUN
admet-698	177	6	)	)	PUNCT
admet-698	177	7	errors	error	NOUN
admet-698	177	8	reported	report	VERB
admet-698	177	9	in	in	ADP
admet-698	177	10	the	the	DET
admet-698	177	11	cheqsol	cheqsol	ADJ
admet-698	177	12	method	method	NOUN
admet-698	177	13	(	(	PUNCT
admet-698	177	14	0.05	0.05	NUM
admet-698	177	15	log	log	NOUN
admet-698	177	16	)	)	PUNCT
admet-698	177	17	need	need	VERB
admet-698	177	18	to	to	PART
admet-698	177	19	be	be	AUX
admet-698	177	20	multiplied	multiply	VERB
admet-698	177	21	by	by	ADP
admet-698	177	22	a	a	DET
admet-698	177	23	factor	factor	NOUN
admet-698	177	24	of	of	ADP
admet-698	177	25	3	3	NUM
admet-698	177	26	to	to	PART
admet-698	177	27	match	match	VERB
admet-698	177	28	the	the	DET
admet-698	177	29	expected	expect	VERB
admet-698	177	30	interlaboratory	interlaboratory	ADJ
admet-698	177	31	errors	error	NOUN
admet-698	177	32	for	for	ADP
admet-698	177	33	the	the	DET
admet-698	177	34	method	method	NOUN
admet-698	177	35	(	(	PUNCT
admet-698	177	36	0.15	0.15	NUM
admet-698	177	37	log	log	NOUN
admet-698	177	38	)	)	PUNCT
admet-698	177	39	.	.	PUNCT
admet-698	178	1	the	the	DET
admet-698	178	2	scale	scale	NOUN
admet-698	178	3	factor	factor	NOUN
admet-698	178	4	,	,	PUNCT
admet-698	178	5	in	in	ADP
admet-698	178	6	part	part	NOUN
admet-698	178	7	,	,	PUNCT
admet-698	178	8	relates	relate	VERB
admet-698	178	9	to	to	ADP
admet-698	178	10	the	the	DET
admet-698	178	11	hidden	hide	VERB
admet-698	178	12	systematic	systematic	ADJ
admet-698	178	13	errors	error	NOUN
admet-698	178	14	in	in	ADP
admet-698	178	15	the	the	DET
admet-698	178	16	single	single	ADJ
admet-698	178	17	-	-	PUNCT
admet-698	178	18	lab	lab	NOUN
admet-698	178	19	values	value	NOUN
admet-698	178	20	.	.	PUNCT
admet-698	179	1	it	it	PRON
admet-698	179	2	is	be	AUX
admet-698	179	3	expected	expect	VERB
admet-698	179	4	that	that	SCONJ
admet-698	179	5	better	well	ADJ
admet-698	179	6	standardizations	standardization	NOUN
admet-698	179	7	in	in	ADP
admet-698	179	8	the	the	DET
admet-698	179	9	‘	'	PUNCT
admet-698	179	10	open	open	ADJ
admet-698	179	11	’	'	PUNCT
admet-698	179	12	ssf	ssf	NOUN
admet-698	179	13	methods	method	NOUN
admet-698	179	14	,	,	PUNCT
admet-698	179	15	as	as	SCONJ
admet-698	179	16	recommended	recommend	VERB
admet-698	179	17	in	in	ADP
admet-698	179	18	the	the	DET
admet-698	179	19	‘	'	PUNCT
admet-698	179	20	white	white	ADJ
admet-698	179	21	paper	paper	NOUN
admet-698	179	22	’	'	PUNCT
admet-698	180	1	[	[	X
admet-698	180	2	3	3	NUM
admet-698	180	3	]	]	PUNCT
admet-698	180	4	,	,	PUNCT
admet-698	180	5	may	may	AUX
admet-698	180	6	equalize	equalize	VERB
admet-698	180	7	the	the	DET
admet-698	180	8	sdi	sdi	PROPN
admet-698	180	9	of	of	ADP
admet-698	180	10	both	both	DET
admet-698	180	11	methods	method	NOUN
admet-698	180	12	at	at	ADP
admet-698	180	13	about	about	ADP
admet-698	180	14	~0.15	~0.15	PUNCT
admet-698	180	15	log	log	NOUN
admet-698	180	16	unit	unit	NOUN
admet-698	180	17	.	.	PUNCT
admet-698	181	1	when	when	SCONJ
admet-698	181	2	solubility	solubility	NOUN
admet-698	181	3	prediction	prediction	NOUN
admet-698	181	4	methods	method	NOUN
admet-698	181	5	indicate	indicate	VERB
admet-698	181	6	rmse	rmse	NOUN
admet-698	181	7	below	below	ADP
admet-698	181	8	0.15	0.15	NUM
admet-698	181	9	,	,	PUNCT
admet-698	181	10	‘	'	PUNCT
admet-698	181	11	overfitting	overfitte	VERB
admet-698	181	12	’	'	PUNCT
admet-698	181	13	is	be	AUX
admet-698	181	14	probably	probably	ADV
admet-698	181	15	taking	take	VERB
admet-698	181	16	place	place	NOUN
admet-698	181	17	,	,	PUNCT
admet-698	181	18	overlapping	overlap	VERB
admet-698	181	19	noise	noise	NOUN
admet-698	181	20	with	with	ADP
admet-698	181	21	information	information	NOUN
admet-698	181	22	.	.	PUNCT
admet-698	182	1	acknowledgement	acknowledgement	NOUN
admet-698	182	2	the	the	DET
admet-698	182	3	commentary	commentary	NOUN
admet-698	182	4	sprang	spring	VERB
admet-698	182	5	out	out	ADP
admet-698	182	6	of	of	ADP
admet-698	182	7	a	a	DET
admet-698	182	8	suggestion	suggestion	NOUN
admet-698	182	9	made	make	VERB
admet-698	182	10	by	by	ADP
admet-698	182	11	a	a	DET
admet-698	182	12	reviewer	reviewer	NOUN
admet-698	182	13	of	of	ADP
admet-698	182	14	the	the	DET
admet-698	182	15	earlier	early	ADJ
admet-698	182	16	paper	paper	NOUN
admet-698	182	17	in	in	ADP
admet-698	182	18	the	the	DET
admet-698	182	19	series	series	NOUN
admet-698	183	1	[	[	X
admet-698	183	2	2	2	NUM
admet-698	183	3	]	]	PUNCT
admet-698	183	4	,	,	PUNCT
admet-698	183	5	that	that	SCONJ
admet-698	183	6	it	it	PRON
admet-698	183	7	would	would	AUX
admet-698	183	8	be	be	AUX
admet-698	183	9	helpful	helpful	ADJ
admet-698	183	10	if	if	SCONJ
admet-698	183	11	a	a	DET
admet-698	183	12	training	training	NOUN
admet-698	183	13	set	set	NOUN
admet-698	183	14	of	of	ADP
admet-698	183	15	data	datum	NOUN
admet-698	183	16	were	be	AUX
admet-698	183	17	provided	provide	VERB
admet-698	183	18	for	for	ADP
admet-698	183	19	the	the	DET
admet-698	183	20	new	new	ADJ
admet-698	183	21	solubility	solubility	NOUN
admet-698	183	22	challenge	challenge	NOUN
admet-698	184	1	[	[	X
admet-698	184	2	2	2	NUM
admet-698	184	3	]	]	PUNCT
admet-698	184	4	.	.	PUNCT
admet-698	185	1	we	we	PRON
admet-698	185	2	are	be	AUX
admet-698	185	3	grateful	grateful	ADJ
admet-698	185	4	for	for	ADP
admet-698	185	5	this	this	DET
admet-698	185	6	good	good	ADJ
admet-698	185	7	thought	thought	NOUN
admet-698	185	8	.	.	PUNCT
admet-698	186	1	conflict	conflict	NOUN
admet-698	186	2	of	of	ADP
admet-698	186	3	interest	interest	NOUN
admet-698	186	4	.	.	PUNCT
admet-698	187	1	none	none	NOUN
admet-698	187	2	.	.	PUNCT
admet-698	188	1	alex	alex	PROPN
admet-698	188	2	avdeef	avdeef	PROPN
admet-698	188	3	admet	admet	PROPN
admet-698	188	4	&	&	CCONJ
admet-698	188	5	dmpk	dmpk	PROPN
admet-698	188	6	7(3	7(3	NUM
admet-698	188	7	)	)	PUNCT
admet-698	188	8	(	(	PUNCT
admet-698	188	9	2019	2019	NUM
admet-698	188	10	)	)	PUNCT
admet-698	188	11	210	210	NUM
admet-698	188	12	-	-	SYM
admet-698	188	13	219	219	NUM
admet-698	188	14	218	218	NUM
admet-698	188	15	references	reference	NOUN
admet-698	188	16	[	[	X
admet-698	188	17	1	1	X
admet-698	188	18	]	]	PUNCT
admet-698	188	19	c.a.s	c.a.s	PROPN
admet-698	188	20	.	.	PROPN
admet-698	188	21	bergström	bergström	NOUN
admet-698	188	22	,	,	PUNCT
admet-698	188	23	a.	a.	NOUN
admet-698	188	24	avdeef	avdeef	PROPN
admet-698	188	25	.	.	PUNCT
admet-698	189	1	perspectives	perspective	NOUN
admet-698	189	2	in	in	ADP
admet-698	189	3	solubility	solubility	NOUN
admet-698	189	4	measurement	measurement	NOUN
admet-698	189	5	and	and	CCONJ
admet-698	189	6	interpretation	interpretation	NOUN
admet-698	189	7	.	.	PUNCT
admet-698	190	1	admet	admet	PROPN
admet-698	190	2	&	&	CCONJ
admet-698	190	3	dmpk	dmpk	PROPN
admet-698	190	4	7	7	NUM
admet-698	190	5	(	(	PUNCT
admet-698	190	6	2019	2019	NUM
admet-698	190	7	)	)	PUNCT
admet-698	190	8	88	88	NUM
admet-698	190	9	-	-	SYM
admet-698	190	10	105	105	NUM
admet-698	190	11	.	.	PUNCT
admet-698	191	1	[	[	X
admet-698	191	2	2	2	NUM
admet-698	191	3	]	]	PUNCT
admet-698	191	4	a.	a.	NOUN
admet-698	191	5	llinas	llinas	PROPN
admet-698	191	6	,	,	PUNCT
admet-698	191	7	a.	a.	NOUN
admet-698	191	8	avdeef	avdeef	PROPN
admet-698	191	9	.	.	PUNCT
admet-698	192	1	solubility	solubility	NOUN
admet-698	192	2	challenge	challenge	NOUN
admet-698	192	3	revisited	revisit	VERB
admet-698	192	4	after	after	ADP
admet-698	192	5	10	10	NUM
admet-698	192	6	years	year	NOUN
admet-698	192	7	,	,	PUNCT
admet-698	192	8	with	with	ADP
admet-698	192	9	multi	multi	ADJ
admet-698	192	10	-	-	ADJ
admet-698	192	11	lab	lab	ADJ
admet-698	192	12	shake	shake	NOUN
admet-698	192	13	-	-	PUNCT
admet-698	192	14	flask	flask	NOUN
admet-698	192	15	data	datum	NOUN
admet-698	192	16	,	,	PUNCT
admet-698	192	17	using	use	VERB
admet-698	192	18	tight	tight	ADJ
admet-698	192	19	(	(	PUNCT
admet-698	192	20	sd	sd	NOUN
admet-698	192	21	~0.17	~0.17	PUNCT
admet-698	192	22	log	log	NOUN
admet-698	192	23	)	)	PUNCT
admet-698	192	24	and	and	CCONJ
admet-698	192	25	loose	loose	ADJ
admet-698	192	26	(	(	PUNCT
admet-698	192	27	sd	sd	NOUN
admet-698	192	28	~0.62	~0.62	SYM
admet-698	192	29	log	log	NOUN
admet-698	192	30	)	)	PUNCT
admet-698	192	31	test	test	NOUN
admet-698	192	32	sets	set	NOUN
admet-698	192	33	,	,	PUNCT
admet-698	192	34	j.	j.	PROPN
admet-698	192	35	chem	chem	PROPN
admet-698	192	36	.	.	PUNCT
admet-698	193	1	inf	inf	PROPN
admet-698	193	2	.	.	PROPN
admet-698	193	3	model	model	PROPN
admet-698	193	4	.	.	PUNCT
admet-698	194	1	(	(	PUNCT
admet-698	194	2	2019	2019	NUM
admet-698	194	3	)	)	PUNCT
admet-698	194	4	.	.	PUNCT
admet-698	195	1	doi	doi	NOUN
admet-698	195	2	:	:	PUNCT
admet-698	195	3	10.1021	10.1021	NUM
admet-698	195	4	/	/	SYM
admet-698	195	5	acs.jcim.9b00345	acs.jcim.9b00345	NOUN
admet-698	195	6	.	.	PUNCT
admet-698	196	1	[	[	X
admet-698	196	2	3	3	NUM
admet-698	196	3	]	]	PUNCT
admet-698	196	4	a.	a.	NOUN
admet-698	196	5	avdeef	avdeef	PROPN
admet-698	196	6	,	,	PUNCT
admet-698	196	7	e.	e.	PROPN
admet-698	196	8	fuguet	fuguet	PROPN
admet-698	196	9	,	,	PUNCT
admet-698	196	10	a.	a.	PROPN
admet-698	196	11	llinàs	llinàs	PROPN
admet-698	196	12	,	,	PUNCT
admet-698	196	13	c.	c.	PROPN
admet-698	196	14	ràfols	ràfols	PROPN
admet-698	196	15	,	,	PUNCT
admet-698	196	16	e.	e.	PROPN
admet-698	196	17	bosch	bosch	PROPN
admet-698	196	18	,	,	PUNCT
admet-698	196	19	g.	g.	PROPN
admet-698	196	20	völgyi	völgyi	PROPN
admet-698	196	21	,	,	PUNCT
admet-698	196	22	t.	t.	NOUN
admet-698	196	23	verbić	verbić	PROPN
admet-698	196	24	,	,	PUNCT
admet-698	196	25	e.	e.	PROPN
admet-698	196	26	boldyreva	boldyreva	PROPN
admet-698	196	27	,	,	PUNCT
admet-698	196	28	k.	k.	PROPN
admet-698	196	29	takács	takács	PROPN
admet-698	196	30	-	-	PUNCT
admet-698	196	31	novák	novák	PROPN
admet-698	196	32	.	.	PUNCT
admet-698	196	33	equilibrium	equilibrium	NOUN
admet-698	196	34	solubility	solubility	NOUN
admet-698	196	35	measurement	measurement	NOUN
admet-698	196	36	of	of	ADP
admet-698	196	37	ionizable	ionizable	ADJ
admet-698	196	38	drugs	drug	NOUN
admet-698	196	39	–	–	PUNCT
admet-698	196	40	consensus	consensus	NOUN
admet-698	196	41	recommendations	recommendation	NOUN
admet-698	196	42	for	for	ADP
admet-698	196	43	improving	improve	VERB
admet-698	196	44	data	datum	NOUN
admet-698	196	45	quality	quality	NOUN
admet-698	196	46	.	.	PUNCT
admet-698	197	1	admet	admet	PROPN
admet-698	197	2	&	&	CCONJ
admet-698	197	3	dmpk	dmpk	PROPN
admet-698	197	4	4	4	NUM
admet-698	197	5	(	(	PUNCT
admet-698	197	6	2016	2016	NUM
admet-698	197	7	)	)	PUNCT
admet-698	197	8	117	117	NUM
admet-698	197	9	-	-	SYM
admet-698	197	10	178	178	NUM
admet-698	197	11	.	.	PUNCT
admet-698	198	1	[	[	X
admet-698	198	2	4	4	X
admet-698	198	3	]	]	PUNCT
admet-698	198	4	c.a.s	c.a.s	PROPN
admet-698	198	5	.	.	PUNCT
admet-698	198	6	bergström	bergström	PROPN
admet-698	198	7	,	,	PUNCT
admet-698	199	1	r.	r.	PROPN
admet-698	199	2	holm	holm	PROPN
admet-698	199	3	,	,	PUNCT
admet-698	199	4	s.a	s.a	PROPN
admet-698	199	5	.	.	PROPN
admet-698	199	6	jørgensen	jørgensen	PROPN
admet-698	199	7	,	,	PUNCT
admet-698	199	8	s.b.e	s.b.e	NOUN
admet-698	199	9	.	.	PUNCT
admet-698	199	10	andersson	andersson	PROPN
admet-698	199	11	,	,	PUNCT
admet-698	199	12	p.	p.	PROPN
admet-698	199	13	artursson	artursson	PROPN
admet-698	199	14	,	,	PUNCT
admet-698	199	15	s.	s.	PROPN
admet-698	199	16	beato	beato	PROPN
admet-698	199	17	,	,	PUNCT
admet-698	199	18	a.	a.	PROPN
admet-698	199	19	borde	borde	PROPN
admet-698	199	20	,	,	PUNCT
admet-698	199	21	k.	k.	PROPN
admet-698	199	22	box	box	PROPN
admet-698	199	23	,	,	PUNCT
admet-698	199	24	m.	m.	NOUN
admet-698	199	25	brewster	brewster	NOUN
admet-698	199	26	,	,	PUNCT
admet-698	199	27	j.	j.	PROPN
admet-698	199	28	dressman	dressman	PROPN
admet-698	199	29	,	,	PUNCT
admet-698	199	30	k.-i	k.-i	PROPN
admet-698	199	31	.	.	PUNCT
admet-698	200	1	feng	feng	PROPN
admet-698	200	2	,	,	PUNCT
admet-698	200	3	g.	g.	PROPN
admet-698	200	4	halbert	halbert	PROPN
admet-698	200	5	,	,	PUNCT
admet-698	200	6	e.	e.	PROPN
admet-698	200	7	kostewicz	kostewicz	PROPN
admet-698	200	8	,	,	PUNCT
admet-698	200	9	m.	m.	NOUN
admet-698	200	10	mcallister	mcallister	PROPN
admet-698	200	11	,	,	PUNCT
admet-698	200	12	u.	u.	PROPN
admet-698	200	13	muenster	muenster	PROPN
admet-698	200	14	,	,	PUNCT
admet-698	200	15	j.	j.	PROPN
admet-698	200	16	thinnes	thinnes	PROPN
admet-698	200	17	,	,	PUNCT
admet-698	200	18	r.	r.	PROPN
admet-698	200	19	taylor	taylor	PROPN
admet-698	200	20	,	,	PUNCT
admet-698	200	21	a.	a.	NOUN
admet-698	200	22	mullertz	mullertz	NOUN
admet-698	200	23	.	.	PUNCT
admet-698	201	1	early	early	ADJ
admet-698	201	2	pharmaceutical	pharmaceutical	NOUN
admet-698	201	3	profiling	profiling	NOUN
admet-698	201	4	to	to	PART
admet-698	201	5	predict	predict	VERB
admet-698	201	6	oral	oral	ADJ
admet-698	201	7	drug	drug	NOUN
admet-698	201	8	absorption	absorption	NOUN
admet-698	201	9	:	:	PUNCT
admet-698	201	10	current	current	ADJ
admet-698	201	11	status	status	NOUN
admet-698	201	12	and	and	CCONJ
admet-698	201	13	unmet	unmet	NOUN
admet-698	201	14	needs	need	NOUN
admet-698	201	15	.	.	PUNCT
admet-698	202	1	eur	eur	PROPN
admet-698	202	2	.	.	PUNCT
admet-698	203	1	j.	j.	PROPN
admet-698	203	2	pharm	pharm	PROPN
admet-698	203	3	.	.	PUNCT
admet-698	204	1	sci	sci	PROPN
admet-698	204	2	.	.	PROPN
admet-698	205	1	57	57	NUM
admet-698	205	2	(	(	PUNCT
admet-698	205	3	2014	2014	NUM
admet-698	205	4	)	)	PUNCT
admet-698	205	5	173	173	NUM
admet-698	205	6	-	-	SYM
admet-698	205	7	199	199	NUM
admet-698	205	8	.	.	PUNCT
admet-698	206	1	[	[	X
admet-698	206	2	5	5	NUM
admet-698	206	3	]	]	X
admet-698	206	4	j.c	j.c	PROPN
admet-698	206	5	.	.	PROPN
admet-698	206	6	dearden	dearden	PROPN
admet-698	206	7	.	.	PUNCT
admet-698	207	1	in	in	ADP
admet-698	207	2	silico	silico	NOUN
admet-698	207	3	prediction	prediction	NOUN
admet-698	207	4	of	of	ADP
admet-698	207	5	aqueous	aqueous	ADJ
admet-698	207	6	solubility	solubility	NOUN
admet-698	207	7	.	.	PUNCT
admet-698	208	1	expert	expert	NOUN
admet-698	208	2	opin	opin	NOUN
admet-698	208	3	.	.	PUNCT
admet-698	209	1	drug	drug	NOUN
admet-698	209	2	discov	discov	NOUN
admet-698	209	3	.	.	PUNCT
admet-698	210	1	1	1	NUM
admet-698	210	2	(	(	PUNCT
admet-698	210	3	2006	2006	NUM
admet-698	210	4	)	)	PUNCT
admet-698	210	5	31–52	31–52	NUM
admet-698	210	6	.	.	PUNCT
admet-698	211	1	[	[	X
admet-698	211	2	6	6	NUM
admet-698	211	3	]	]	PUNCT
admet-698	211	4	j.	j.	PROPN
admet-698	211	5	taskinen	taskinen	PROPN
admet-698	211	6	,	,	PUNCT
admet-698	211	7	u.	u.	PROPN
admet-698	211	8	norinder	norinder	PROPN
admet-698	211	9	.	.	PUNCT
admet-698	212	1	in	in	ADP
admet-698	212	2	silico	silico	NOUN
admet-698	212	3	prediction	prediction	NOUN
admet-698	212	4	of	of	ADP
admet-698	212	5	solubility	solubility	NOUN
admet-698	212	6	.	.	PUNCT
admet-698	213	1	in	in	ADP
admet-698	213	2	:	:	PUNCT
admet-698	213	3	b.	b.	PROPN
admet-698	213	4	testa	testa	PROPN
admet-698	213	5	,	,	PUNCT
admet-698	213	6	h.	h.	PROPN
admet-698	213	7	van	van	PROPN
admet-698	213	8	de	de	PROPN
admet-698	213	9	waterbeemd	waterbeemd	PROPN
admet-698	213	10	(	(	PUNCT
admet-698	213	11	eds	ed	NOUN
admet-698	213	12	.	.	PUNCT
admet-698	213	13	)	)	PUNCT
admet-698	213	14	.	.	PUNCT
admet-698	214	1	comprehensive	comprehensive	ADJ
admet-698	214	2	medicinal	medicinal	PROPN
admet-698	214	3	chemistry	chemistry	PROPN
admet-698	214	4	ii	ii	PROPN
admet-698	214	5	,	,	PUNCT
admet-698	214	6	elsevier	elsevier	NOUN
admet-698	214	7	:	:	PUNCT
admet-698	214	8	oxford	oxford	PROPN
admet-698	214	9	,	,	PUNCT
admet-698	214	10	uk	uk	PROPN
admet-698	214	11	,	,	PUNCT
admet-698	214	12	2007	2007	NUM
admet-698	214	13	,	,	PUNCT
admet-698	214	14	pp	pp	ADJ
admet-698	214	15	.	.	PUNCT
admet-698	215	1	627	627	NUM
admet-698	215	2	-	-	SYM
admet-698	215	3	648	648	NUM
admet-698	215	4	.	.	PUNCT
admet-698	216	1	[	[	X
admet-698	216	2	7	7	NUM
admet-698	216	3	]	]	PUNCT
admet-698	216	4	a.	a.	NOUN
admet-698	216	5	avdeef	avdeef	PROPN
admet-698	216	6	.	.	PUNCT
admet-698	217	1	ph	ph	VERB
admet-698	217	2	-	-	ADJ
admet-698	217	3	metric	metric	ADJ
admet-698	217	4	solubility	solubility	NOUN
admet-698	217	5	.	.	PUNCT
admet-698	218	1	1	1	X
admet-698	218	2	.	.	X
admet-698	218	3	solubility	solubility	NOUN
admet-698	218	4	-	-	PUNCT
admet-698	218	5	ph	ph	NOUN
admet-698	218	6	profiles	profile	NOUN
admet-698	218	7	from	from	ADP
admet-698	218	8	bjerrum	bjerrum	NOUN
admet-698	218	9	plots	plot	NOUN
admet-698	218	10	.	.	PUNCT
admet-698	219	1	gibbs	gibbs	PROPN
admet-698	219	2	buffer	buffer	NOUN
admet-698	219	3	and	and	CCONJ
admet-698	219	4	pka	pka	VERB
admet-698	219	5	in	in	ADP
admet-698	219	6	the	the	DET
admet-698	219	7	solid	solid	ADJ
admet-698	219	8	state	state	NOUN
admet-698	219	9	.	.	PUNCT
admet-698	220	1	pharm	pharm	NOUN
admet-698	220	2	.	.	PUNCT
admet-698	221	1	pharmacol	pharmacol	PROPN
admet-698	221	2	.	.	PUNCT
admet-698	222	1	commun	commun	PROPN
admet-698	222	2	.	.	PUNCT
admet-698	223	1	4	4	NUM
admet-698	223	2	(	(	PUNCT
admet-698	223	3	1998	1998	NUM
admet-698	223	4	)	)	PUNCT
admet-698	223	5	165	165	NUM
admet-698	223	6	-	-	SYM
admet-698	223	7	178	178	NUM
admet-698	223	8	.	.	PUNCT
admet-698	224	1	[	[	X
admet-698	224	2	8	8	NUM
admet-698	224	3	]	]	PUNCT
admet-698	224	4	a.	a.	NOUN
admet-698	224	5	avdeef	avdeef	PROPN
admet-698	224	6	,	,	PUNCT
admet-698	224	7	c.m	c.m	PROPN
admet-698	224	8	.	.	PROPN
admet-698	224	9	berger	berger	PROPN
admet-698	224	10	,	,	PUNCT
admet-698	224	11	c.	c.	PROPN
admet-698	224	12	brownell	brownell	PROPN
admet-698	224	13	.	.	PUNCT
admet-698	225	1	ph	ph	ADJ
admet-698	225	2	-	-	ADJ
admet-698	225	3	metric	metric	ADJ
admet-698	225	4	solubility	solubility	NOUN
admet-698	225	5	.	.	PUNCT
admet-698	226	1	2	2	X
admet-698	226	2	.	.	X
admet-698	226	3	correlation	correlation	NOUN
admet-698	226	4	between	between	ADP
admet-698	226	5	the	the	DET
admet-698	226	6	acid	acid	NOUN
admet-698	226	7	-	-	PUNCT
admet-698	226	8	base	base	NOUN
admet-698	226	9	titration	titration	NOUN
admet-698	226	10	and	and	CCONJ
admet-698	226	11	the	the	DET
admet-698	226	12	saturation	saturation	NOUN
admet-698	226	13	shake	shake	NOUN
admet-698	226	14	-	-	PUNCT
admet-698	226	15	flask	flask	NOUN
admet-698	226	16	solubility	solubility	NOUN
admet-698	226	17	-	-	PUNCT
admet-698	226	18	ph	ph	ADJ
admet-698	226	19	methods	method	NOUN
admet-698	226	20	.	.	PUNCT
admet-698	227	1	pharm	pharm	NOUN
admet-698	227	2	.	.	PUNCT
admet-698	228	1	res	re	NOUN
admet-698	228	2	.	.	PROPN
admet-698	229	1	17	17	NUM
admet-698	229	2	(	(	PUNCT
admet-698	229	3	2000	2000	NUM
admet-698	229	4	)	)	PUNCT
admet-698	229	5	85	85	NUM
admet-698	229	6	-	-	SYM
admet-698	229	7	89	89	NUM
admet-698	229	8	.	.	PUNCT
admet-698	230	1	[	[	X
admet-698	230	2	9	9	NUM
admet-698	230	3	]	]	PUNCT
admet-698	230	4	m.	m.	NOUN
admet-698	230	5	stuart	stuart	PROPN
admet-698	230	6	,	,	PUNCT
admet-698	230	7	k.	k.	PROPN
admet-698	230	8	box	box	PROPN
admet-698	230	9	.	.	PUNCT
admet-698	231	1	chasing	chase	VERB
admet-698	231	2	equilibrium	equilibrium	NOUN
admet-698	231	3	:	:	PUNCT
admet-698	231	4	measuring	measure	VERB
admet-698	231	5	the	the	DET
admet-698	231	6	intrinsic	intrinsic	ADJ
admet-698	231	7	solubility	solubility	NOUN
admet-698	231	8	of	of	ADP
admet-698	231	9	weak	weak	ADJ
admet-698	231	10	acids	acid	NOUN
admet-698	231	11	and	and	CCONJ
admet-698	231	12	bases	basis	NOUN
admet-698	231	13	.	.	PUNCT
admet-698	232	1	anal	anal	ADJ
admet-698	232	2	.	.	PUNCT
admet-698	232	3	chem	chem	PROPN
admet-698	232	4	.	.	PUNCT
admet-698	233	1	77	77	NUM
admet-698	233	2	(	(	PUNCT
admet-698	233	3	2005	2005	NUM
admet-698	233	4	)	)	PUNCT
admet-698	233	5	983	983	NUM
admet-698	233	6	-	-	SYM
admet-698	233	7	990	990	NUM
admet-698	233	8	.	.	PUNCT
admet-698	234	1	[	[	X
admet-698	234	2	10	10	NUM
admet-698	234	3	]	]	X
admet-698	234	4	o.s	o.s	PROPN
admet-698	234	5	.	.	PROPN
admet-698	234	6	marković	marković	PROPN
admet-698	234	7	,	,	PUNCT
admet-698	234	8	m.p	m.p	PROPN
admet-698	234	9	.	.	PROPN
admet-698	234	10	pešić	pešić	PROPN
admet-698	234	11	,	,	PUNCT
admet-698	234	12	a.v	a.v	PROPN
admet-698	234	13	.	.	PROPN
admet-698	234	14	shah	shah	PROPN
admet-698	234	15	,	,	PUNCT
admet-698	234	16	a.t.m	a.t.m	PROPN
admet-698	234	17	.	.	PUNCT
admet-698	235	1	serajuddin	serajuddin	PROPN
admet-698	235	2	,	,	PUNCT
admet-698	235	3	t.z	t.z	PROPN
admet-698	235	4	.	.	PROPN
admet-698	235	5	verbić	verbić	PROPN
admet-698	235	6	,	,	PUNCT
admet-698	235	7	a.	a.	NOUN
admet-698	235	8	avdeef	avdeef	PROPN
admet-698	235	9	.	.	PUNCT
admet-698	236	1	solubility	solubility	NOUN
admet-698	236	2	-	-	PUNCT
admet-698	236	3	ph	ph	NOUN
admet-698	236	4	profile	profile	NOUN
admet-698	236	5	of	of	ADP
admet-698	236	6	desipramine	desipramine	NOUN
admet-698	236	7	hydrochloride	hydrochloride	NOUN
admet-698	236	8	in	in	ADP
admet-698	236	9	saline	saline	ADJ
admet-698	236	10	phosphate	phosphate	NOUN
admet-698	236	11	buffer	buffer	NOUN
admet-698	236	12	:	:	PUNCT
admet-698	236	13	enhanced	enhance	VERB
admet-698	236	14	solubility	solubility	NOUN
admet-698	236	15	due	due	ADP
admet-698	236	16	to	to	ADP
admet-698	236	17	drug	drug	NOUN
admet-698	236	18	-	-	PUNCT
admet-698	236	19	buffer	buffer	NOUN
admet-698	236	20	aggregates	aggregate	NOUN
admet-698	236	21	.	.	PUNCT
admet-698	237	1	eur	eur	PROPN
admet-698	237	2	.	.	PUNCT
admet-698	238	1	j.	j.	PROPN
admet-698	238	2	pharm	pharm	PROPN
admet-698	238	3	.	.	PUNCT
admet-698	239	1	sci	sci	PROPN
admet-698	239	2	.	.	PROPN
admet-698	240	1	133	133	NUM
admet-698	240	2	(	(	PUNCT
admet-698	240	3	2019	2019	NUM
admet-698	240	4	)	)	PUNCT
admet-698	240	5	264	264	NUM
admet-698	240	6	-	-	SYM
admet-698	240	7	274	274	NUM
admet-698	240	8	.	.	PUNCT
admet-698	241	1	[	[	X
admet-698	241	2	11	11	NUM
admet-698	241	3	]	]	PUNCT
admet-698	241	4	a.	a.	NOUN
admet-698	241	5	pobudkowska	pobudkowska	PROPN
admet-698	241	6	,	,	PUNCT
admet-698	241	7	c.	c.	PROPN
admet-698	241	8	ràfols	ràfol	NOUN
admet-698	241	9	,	,	PUNCT
admet-698	241	10	x.	x.	NOUN
admet-698	241	11	subirats	subirats	PROPN
admet-698	241	12	,	,	PUNCT
admet-698	241	13	e.	e.	PROPN
admet-698	241	14	bosch	bosch	PROPN
admet-698	241	15	,	,	PUNCT
admet-698	241	16	a.	a.	PROPN
admet-698	241	17	avdeef	avdeef	PROPN
admet-698	241	18	.	.	PUNCT
admet-698	242	1	phenothiazines	phenothiazine	NOUN
admet-698	242	2	solution	solution	NOUN
admet-698	242	3	complexity	complexity	NOUN
admet-698	242	4	–	–	PUNCT
admet-698	242	5	determination	determination	NOUN
admet-698	242	6	of	of	ADP
admet-698	242	7	pka	pka	PROPN
admet-698	242	8	and	and	CCONJ
admet-698	242	9	solubility	solubility	NOUN
admet-698	242	10	-	-	PUNCT
admet-698	242	11	ph	ph	ADJ
admet-698	242	12	profiles	profile	NOUN
admet-698	242	13	exhibiting	exhibit	VERB
admet-698	242	14	sub	sub	ADJ
admet-698	242	15	-	-	ADJ
admet-698	242	16	micellar	micellar	ADJ
admet-698	242	17	aggregation	aggregation	NOUN
admet-698	242	18	at	at	ADP
admet-698	242	19	25	25	NUM
admet-698	242	20	and	and	CCONJ
admet-698	242	21	37	37	NUM
admet-698	242	22	o	o	PROPN
admet-698	242	23	c.	c.	PROPN
admet-698	242	24	eur	eur	PROPN
admet-698	242	25	.	.	PUNCT
admet-698	243	1	j.	j.	PROPN
admet-698	243	2	pharm	pharm	PROPN
admet-698	243	3	.	.	PUNCT
admet-698	244	1	sci	sci	PROPN
admet-698	244	2	.	.	PROPN
admet-698	245	1	93	93	NUM
admet-698	245	2	(	(	PUNCT
admet-698	245	3	2016	2016	NUM
admet-698	245	4	)	)	PUNCT
admet-698	245	5	163	163	NUM
admet-698	245	6	-	-	SYM
admet-698	245	7	176	176	NUM
admet-698	245	8	.	.	PUNCT
admet-698	246	1	[	[	X
admet-698	246	2	12	12	NUM
admet-698	246	3	]	]	X
admet-698	246	4	e.	e.	PROPN
admet-698	246	5	shoghi	shoghi	PROPN
admet-698	246	6	,	,	PUNCT
admet-698	246	7	e.	e.	PROPN
admet-698	246	8	fuguet	fuguet	PROPN
admet-698	246	9	,	,	PUNCT
admet-698	246	10	e.	e.	PROPN
admet-698	246	11	bosch	bosch	PROPN
admet-698	246	12	,	,	PUNCT
admet-698	246	13	c.	c.	PROPN
admet-698	246	14	ràfols	ràfol	NOUN
admet-698	246	15	.	.	PUNCT
admet-698	247	1	solubility	solubility	NOUN
admet-698	247	2	-	-	PUNCT
admet-698	247	3	ph	ph	NOUN
admet-698	247	4	profile	profile	NOUN
admet-698	247	5	of	of	ADP
admet-698	247	6	some	some	DET
admet-698	247	7	acidic	acidic	ADJ
admet-698	247	8	,	,	PUNCT
admet-698	247	9	basic	basic	ADJ
admet-698	247	10	and	and	CCONJ
admet-698	247	11	amphoteric	amphoteric	ADJ
admet-698	247	12	drugs	drug	NOUN
admet-698	247	13	.	.	PUNCT
admet-698	248	1	eur	eur	PROPN
admet-698	248	2	.	.	PUNCT
admet-698	249	1	j.	j.	PROPN
admet-698	249	2	pharm	pharm	PROPN
admet-698	249	3	.	.	PUNCT
admet-698	250	1	sci	sci	PROPN
admet-698	250	2	.	.	PROPN
admet-698	251	1	48	48	NUM
admet-698	251	2	(	(	PUNCT
admet-698	251	3	2012	2012	NUM
admet-698	251	4	)	)	PUNCT
admet-698	251	5	290	290	NUM
admet-698	251	6	-	-	SYM
admet-698	251	7	300	300	NUM
admet-698	251	8	.	.	PUNCT
admet-698	252	1	[	[	X
admet-698	252	2	13	13	NUM
admet-698	252	3	]	]	X
admet-698	252	4	g.	g.	PROPN
admet-698	252	5	zografi	zografi	PROPN
admet-698	252	6	,	,	PUNCT
admet-698	252	7	i.	i.	PROPN
admet-698	252	8	zarenda	zarenda	PROPN
admet-698	252	9	.	.	PUNCT
admet-698	253	1	the	the	DET
admet-698	253	2	surface	surface	NOUN
admet-698	253	3	activity	activity	NOUN
admet-698	253	4	of	of	ADP
admet-698	253	5	phenothiazine	phenothiazine	NOUN
admet-698	253	6	derivatives	derivative	NOUN
admet-698	253	7	at	at	ADP
admet-698	253	8	the	the	DET
admet-698	253	9	air	air	NOUN
admet-698	253	10	-	-	PUNCT
admet-698	253	11	solution	solution	NOUN
admet-698	253	12	interface	interface	NOUN
admet-698	253	13	.	.	PUNCT
admet-698	254	1	biochem	biochem	PROPN
admet-698	254	2	.	.	PUNCT
admet-698	255	1	pharmacol	pharmacol	PROPN
admet-698	255	2	.	.	PROPN
admet-698	256	1	15	15	NUM
admet-698	256	2	(	(	PUNCT
admet-698	256	3	1966	1966	NUM
admet-698	256	4	)	)	PUNCT
admet-698	256	5	,	,	PUNCT
admet-698	257	1	591–598	591–598	NUM
admet-698	257	2	.	.	PUNCT
admet-698	258	1	[	[	X
admet-698	258	2	14	14	NUM
admet-698	258	3	]	]	PUNCT
admet-698	258	4	a.	a.	NOUN
admet-698	258	5	avdeef	avdeef	PROPN
admet-698	258	6	.	.	PUNCT
admet-698	259	1	absorption	absorption	NOUN
admet-698	259	2	and	and	CCONJ
admet-698	259	3	drug	drug	NOUN
admet-698	259	4	development	development	PROPN
admet-698	259	5	second	second	PROPN
admet-698	259	6	edition	edition	NOUN
admet-698	259	7	,	,	PUNCT
admet-698	259	8	wiley	wiley	NOUN
admet-698	259	9	-	-	PUNCT
admet-698	259	10	interscience	interscience	PROPN
admet-698	259	11	,	,	PUNCT
admet-698	259	12	hoboken	hoboken	PROPN
admet-698	259	13	nj	nj	PROPN
admet-698	259	14	,	,	PUNCT
admet-698	259	15	2012	2012	NUM
admet-698	259	16	,	,	PUNCT
admet-698	259	17	ch	ch	NOUN
admet-698	259	18	.	.	PROPN
admet-698	259	19	6	6	NUM
admet-698	259	20	.	.	PUNCT
admet-698	260	1	[	[	X
admet-698	260	2	15	15	NUM
admet-698	260	3	]	]	PUNCT
admet-698	260	4	a.	a.	NOUN
admet-698	260	5	avdeef	avdeef	PROPN
admet-698	260	6	.	.	PUNCT
admet-698	261	1	solubility	solubility	NOUN
admet-698	261	2	temperature	temperature	NOUN
admet-698	261	3	dependence	dependence	NOUN
admet-698	261	4	predicted	predict	VERB
admet-698	261	5	from	from	ADP
admet-698	261	6	2d	2d	NUM
admet-698	261	7	structure	structure	NOUN
admet-698	261	8	.	.	PUNCT
admet-698	262	1	admet	admet	PROPN
admet-698	262	2	&	&	CCONJ
admet-698	262	3	dmpk	dmpk	PROPN
admet-698	262	4	3	3	NUM
admet-698	262	5	(	(	PUNCT
admet-698	262	6	2015	2015	NUM
admet-698	262	7	)	)	PUNCT
admet-698	262	8	298	298	NUM
admet-698	262	9	-	-	SYM
admet-698	262	10	344	344	NUM
admet-698	262	11	.	.	PUNCT
admet-698	263	1	[	[	X
admet-698	263	2	16	16	NUM
admet-698	263	3	]	]	PUNCT
admet-698	263	4	a.	a.	NOUN
admet-698	263	5	llinàs	llinàs	PROPN
admet-698	263	6	,	,	PUNCT
admet-698	263	7	r.c	r.c	PROPN
admet-698	263	8	.	.	PROPN
admet-698	263	9	glen	glen	PROPN
admet-698	263	10	,	,	PUNCT
admet-698	263	11	j.m	j.m	PROPN
admet-698	263	12	.	.	PROPN
admet-698	263	13	goodman	goodman	PROPN
admet-698	263	14	.	.	PUNCT
admet-698	264	1	solubility	solubility	NOUN
admet-698	264	2	challenge	challenge	NOUN
admet-698	264	3	:	:	PUNCT
admet-698	264	4	can	can	AUX
admet-698	264	5	you	you	PRON
admet-698	264	6	predict	predict	VERB
admet-698	264	7	solubilities	solubility	NOUN
admet-698	264	8	of	of	ADP
admet-698	264	9	32	32	NUM
admet-698	264	10	molecules	molecule	NOUN
admet-698	264	11	using	use	VERB
admet-698	264	12	a	a	DET
admet-698	264	13	database	database	NOUN
admet-698	264	14	of	of	ADP
admet-698	264	15	100	100	NUM
admet-698	264	16	reliable	reliable	ADJ
admet-698	264	17	measurements	measurement	NOUN
admet-698	264	18	?	?	PUNCT
admet-698	265	1	j.	j.	PROPN
admet-698	265	2	chem	chem	PROPN
admet-698	265	3	.	.	PUNCT
admet-698	266	1	inf	inf	PROPN
admet-698	266	2	.	.	PROPN
admet-698	266	3	model	model	PROPN
admet-698	266	4	.	.	PUNCT
admet-698	267	1	48	48	NUM
admet-698	267	2	(	(	PUNCT
admet-698	267	3	2008	2008	NUM
admet-698	267	4	)	)	PUNCT
admet-698	267	5	1289	1289	NUM
admet-698	267	6	-	-	SYM
admet-698	267	7	1303	1303	NUM
admet-698	267	8	.	.	PUNCT
admet-698	268	1	[	[	X
admet-698	268	2	17	17	NUM
admet-698	268	3	]	]	X
admet-698	268	4	a.j	a.j	PROPN
admet-698	268	5	.	.	PROPN
admet-698	268	6	hopfinger	hopfinger	PROPN
admet-698	268	7	,	,	PUNCT
admet-698	268	8	e.x	e.x	PROPN
admet-698	268	9	.	.	PROPN
admet-698	268	10	esposito	esposito	PROPN
admet-698	268	11	,	,	PUNCT
admet-698	268	12	a.	a.	PROPN
admet-698	268	13	llinàs	llinàs	PROPN
admet-698	268	14	,	,	PUNCT
admet-698	268	15	r.c	r.c	PROPN
admet-698	268	16	.	.	PROPN
admet-698	268	17	glen	glen	PROPN
admet-698	268	18	,	,	PUNCT
admet-698	268	19	j.m	j.m	PROPN
admet-698	268	20	.	.	PROPN
admet-698	268	21	goodman	goodman	PROPN
admet-698	268	22	.	.	PUNCT
admet-698	269	1	findings	finding	NOUN
admet-698	269	2	of	of	ADP
admet-698	269	3	the	the	DET
admet-698	269	4	challenge	challenge	NOUN
admet-698	269	5	to	to	PART
admet-698	269	6	predict	predict	VERB
admet-698	269	7	aqueous	aqueous	ADJ
admet-698	269	8	solubility	solubility	NOUN
admet-698	269	9	.	.	PUNCT
admet-698	270	1	j.	j.	PROPN
admet-698	270	2	chem	chem	PROPN
admet-698	270	3	.	.	PUNCT
admet-698	271	1	inf	inf	PROPN
admet-698	271	2	.	.	PROPN
admet-698	271	3	model	model	PROPN
admet-698	271	4	.	.	PUNCT
admet-698	272	1	49	49	NUM
admet-698	272	2	(	(	PUNCT
admet-698	272	3	2009	2009	NUM
admet-698	272	4	)	)	PUNCT
admet-698	272	5	1	1	NUM
admet-698	272	6	-	-	SYM
admet-698	272	7	5	5	NUM
admet-698	272	8	.	.	PUNCT
admet-698	273	1	[	[	X
admet-698	273	2	18	18	NUM
admet-698	273	3	]	]	X
admet-698	273	4	a.r	a.r	PROPN
admet-698	273	5	.	.	PROPN
admet-698	273	6	katritzky	katritzky	PROPN
admet-698	273	7	,	,	PUNCT
admet-698	273	8	y.	y.	PROPN
admet-698	273	9	wang	wang	PROPN
admet-698	273	10	,	,	PUNCT
admet-698	273	11	s.	s.	PROPN
admet-698	273	12	sild	sild	PROPN
admet-698	273	13	,	,	PUNCT
admet-698	273	14	t.	t.	PROPN
admet-698	273	15	tamm	tamm	PROPN
admet-698	273	16	,	,	PUNCT
admet-698	273	17	m.	m.	PROPN
admet-698	273	18	karelson	karelson	PROPN
admet-698	273	19	.	.	PROPN
admet-698	274	1	qspr	qspr	PROPN
admet-698	274	2	studies	study	NOUN
admet-698	274	3	on	on	ADP
admet-698	274	4	vapor	vapor	NOUN
admet-698	274	5	pressure	pressure	NOUN
admet-698	274	6	,	,	PUNCT
admet-698	274	7	aqueous	aqueous	ADJ
admet-698	274	8	solubility	solubility	NOUN
admet-698	274	9	,	,	PUNCT
admet-698	274	10	and	and	CCONJ
admet-698	274	11	the	the	DET
admet-698	274	12	prediction	prediction	NOUN
admet-698	274	13	of	of	ADP
admet-698	274	14	water	water	NOUN
admet-698	274	15	-	-	PUNCT
admet-698	274	16	air	air	NOUN
admet-698	274	17	partition	partition	NOUN
admet-698	274	18	coefficients	coefficient	NOUN
admet-698	274	19	.	.	PUNCT
admet-698	275	1	j.	j.	PROPN
admet-698	275	2	chem	chem	PROPN
admet-698	275	3	.	.	PUNCT
admet-698	276	1	inf	inf	PROPN
admet-698	276	2	.	.	PROPN
admet-698	276	3	model	model	PROPN
admet-698	276	4	.	.	PUNCT
admet-698	277	1	38	38	NUM
admet-698	277	2	(	(	PUNCT
admet-698	277	3	1998	1998	NUM
admet-698	277	4	)	)	PUNCT
admet-698	277	5	720725	720725	NUM
admet-698	277	6	.	.	PUNCT
admet-698	278	1	[	[	X
admet-698	278	2	19	19	NUM
admet-698	278	3	]	]	PUNCT
admet-698	278	4	a.	a.	NOUN
admet-698	278	5	avdeef	avdeef	PROPN
admet-698	278	6	.	.	PUNCT
admet-698	279	1	suggested	suggest	VERB
admet-698	279	2	improvements	improvement	NOUN
admet-698	279	3	for	for	ADP
admet-698	279	4	measurement	measurement	NOUN
admet-698	279	5	of	of	ADP
admet-698	279	6	equilibrium	equilibrium	NOUN
admet-698	279	7	solubility	solubility	NOUN
admet-698	279	8	-	-	PUNCT
admet-698	279	9	ph	ph	NOUN
admet-698	279	10	of	of	ADP
admet-698	279	11	ionizable	ionizable	ADJ
admet-698	279	12	drugs	drug	NOUN
admet-698	279	13	.	.	PUNCT
admet-698	280	1	admet	admet	PROPN
admet-698	280	2	&	&	CCONJ
admet-698	280	3	dmpk	dmpk	PROPN
admet-698	280	4	3	3	NUM
admet-698	280	5	(	(	PUNCT
admet-698	280	6	2015	2015	NUM
admet-698	280	7	)	)	PUNCT
admet-698	280	8	84	84	NUM
admet-698	280	9	-	-	SYM
admet-698	280	10	109	109	NUM
admet-698	280	11	.	.	PUNCT
admet-698	281	1	[	[	X
admet-698	281	2	20	20	NUM
admet-698	281	3	]	]	PUNCT
admet-698	281	4	g.	g.	PROPN
admet-698	281	5	völgyi	völgyi	PROPN
admet-698	281	6	,	,	PUNCT
admet-698	281	7	a.	a.	NOUN
admet-698	281	8	marosi	marosi	PROPN
admet-698	281	9	,	,	PUNCT
admet-698	281	10	k.	k.	PROPN
admet-698	281	11	takács	takács	PROPN
admet-698	281	12	-	-	PUNCT
admet-698	281	13	novák	novák	PROPN
admet-698	281	14	,	,	PUNCT
admet-698	281	15	a.	a.	NOUN
admet-698	281	16	avdeef	avdeef	PROPN
admet-698	281	17	.	.	PUNCT
admet-698	282	1	salt	salt	NOUN
admet-698	282	2	solubility	solubility	NOUN
admet-698	282	3	products	product	NOUN
admet-698	282	4	of	of	ADP
admet-698	282	5	diprenorphine	diprenorphine	NOUN
admet-698	282	6	hydrochloride	hydrochloride	NOUN
admet-698	282	7	,	,	PUNCT
admet-698	282	8	codeine	codeine	NOUN
admet-698	282	9	and	and	CCONJ
admet-698	282	10	lidocaine	lidocaine	NOUN
admet-698	282	11	hydrochlorides	hydrochloride	NOUN
admet-698	282	12	and	and	CCONJ
admet-698	282	13	phosphates	phosphate	NOUN
admet-698	282	14	–	–	PUNCT
admet-698	282	15	novel	novel	NOUN
admet-698	282	16	method	method	NOUN
admet-698	282	17	of	of	ADP
admet-698	282	18	data	datum	NOUN
admet-698	282	19	analysis	analysis	NOUN
admet-698	282	20	not	not	PART
admet-698	282	21	dependent	dependent	ADJ
admet-698	282	22	on	on	ADP
admet-698	282	23	explicit	explicit	ADJ
admet-698	282	24	solubility	solubility	NOUN
admet-698	282	25	equations	equation	NOUN
admet-698	282	26	.	.	PUNCT
admet-698	283	1	admet	admet	PROPN
admet-698	283	2	&	&	CCONJ
admet-698	283	3	dmpk	dmpk	PROPN
admet-698	283	4	1	1	NUM
admet-698	283	5	(	(	PUNCT
admet-698	283	6	2013	2013	NUM
admet-698	283	7	)	)	PUNCT
admet-698	283	8	48	48	NUM
admet-698	283	9	-	-	SYM
admet-698	283	10	62	62	NUM
admet-698	283	11	.	.	PUNCT
admet-698	284	1	admet	admet	PROPN
admet-698	284	2	&	&	CCONJ
admet-698	284	3	dmpk	dmpk	PROPN
admet-698	284	4	7(3	7(3	NUM
admet-698	284	5	)	)	PUNCT
admet-698	284	6	(	(	PUNCT
admet-698	284	7	2019	2019	NUM
admet-698	284	8	)	)	PUNCT
admet-698	284	9	210	210	NUM
admet-698	284	10	-	-	SYM
admet-698	284	11	219	219	NUM
admet-698	284	12	multi	multi	ADJ
admet-698	284	13	-	-	ADJ
admet-698	284	14	lab	lab	ADJ
admet-698	284	15	log	log	NOUN
admet-698	284	16	s0	s0	PROPN
admet-698	284	17	measurement	measurement	PROPN
admet-698	284	18	reproducibility	reproducibility	NOUN
admet-698	284	19	in	in	ADP
admet-698	284	20	cheqsol	cheqsol	NOUN
admet-698	284	21	and	and	CCONJ
admet-698	284	22	shake	shake	NOUN
admet-698	284	23	-	-	PUNCT
admet-698	284	24	flask	flask	NOUN
admet-698	284	25	methods	method	NOUN
admet-698	284	26	doi	doi	NOUN
admet-698	284	27	:	:	PUNCT
admet-698	284	28	10.5599	10.5599	NUM
admet-698	284	29	/	/	SYM
admet-698	284	30	admet.698	admet.698	NOUN
admet-698	284	31	219	219	NUM
admet-698	285	1	[	[	X
admet-698	285	2	21	21	NUM
admet-698	285	3	]	]	PUNCT
admet-698	285	4	k.	k.	PROPN
admet-698	285	5	baek	baek	PROPN
admet-698	285	6	,	,	PUNCT
admet-698	285	7	s.b	s.b	PROPN
admet-698	285	8	.	.	PROPN
admet-698	285	9	jeon	jeon	PROPN
admet-698	285	10	,	,	PUNCT
admet-698	285	11	b.k	b.k	PROPN
admet-698	285	12	.	.	PROPN
admet-698	285	13	kim	kim	PROPN
admet-698	285	14	,	,	PUNCT
admet-698	285	15	n.s	n.s	PROPN
admet-698	285	16	.	.	PROPN
admet-698	285	17	kang	kang	PROPN
admet-698	285	18	.	.	PUNCT
admet-698	286	1	method	method	PROPN
admet-698	286	2	validation	validation	NOUN
admet-698	286	3	for	for	ADP
admet-698	286	4	equilibrium	equilibrium	NOUN
admet-698	286	5	solubility	solubility	NOUN
admet-698	286	6	and	and	CCONJ
admet-698	286	7	determination	determination	NOUN
admet-698	286	8	of	of	ADP
admet-698	286	9	temperature	temperature	NOUN
admet-698	286	10	effect	effect	NOUN
admet-698	286	11	on	on	ADP
admet-698	286	12	the	the	DET
admet-698	286	13	ionization	ionization	NOUN
admet-698	286	14	constant	constant	ADJ
admet-698	286	15	and	and	CCONJ
admet-698	286	16	intrinsic	intrinsic	ADJ
admet-698	286	17	solubility	solubility	NOUN
admet-698	286	18	of	of	ADP
admet-698	286	19	drugs	drug	NOUN
admet-698	286	20	.	.	PUNCT
admet-698	287	1	j.	j.	PROPN
admet-698	287	2	pharm	pharm	PROPN
admet-698	287	3	.	.	PUNCT
admet-698	288	1	sci	sci	PROPN
admet-698	288	2	.	.	PUNCT
admet-698	288	3	emerg	emerg	PROPN
admet-698	288	4	.	.	PUNCT
admet-698	289	1	drugs	drug	NOUN
admet-698	289	2	6	6	NUM
admet-698	289	3	(	(	PUNCT
admet-698	289	4	2018	2018	NUM
admet-698	289	5	)	)	PUNCT
admet-698	289	6	1	1	NUM
admet-698	289	7	-	-	SYM
admet-698	289	8	6	6	NUM
admet-698	289	9	.	.	PUNCT
admet-698	290	1	[	[	X
admet-698	290	2	22	22	NUM
admet-698	290	3	]	]	X
admet-698	290	4	k.j	k.j	PROPN
admet-698	290	5	.	.	PROPN
admet-698	290	6	box	box	PROPN
admet-698	290	7	,	,	PUNCT
admet-698	290	8	j.e.a	j.e.a	PROPN
admet-698	290	9	.	.	PUNCT
admet-698	290	10	comer	comer	NOUN
admet-698	290	11	.	.	PUNCT
admet-698	291	1	using	use	VERB
admet-698	291	2	measured	measured	ADJ
admet-698	291	3	pka	pka	PROPN
admet-698	291	4	,	,	PUNCT
admet-698	291	5	log	log	VERB
admet-698	291	6	p	p	NOUN
admet-698	291	7	and	and	CCONJ
admet-698	291	8	solubility	solubility	NOUN
admet-698	291	9	to	to	PART
admet-698	291	10	investigate	investigate	VERB
admet-698	291	11	supersaturation	supersaturation	NOUN
admet-698	291	12	and	and	CCONJ
admet-698	291	13	predict	predict	VERB
admet-698	291	14	bcs	bcs	NOUN
admet-698	291	15	class	class	NOUN
admet-698	291	16	.	.	PUNCT
admet-698	292	1	curr	curr	PROPN
admet-698	292	2	.	.	PUNCT
admet-698	292	3	drug	drug	PROPN
admet-698	292	4	metab	metab	NOUN
admet-698	292	5	.	.	PUNCT
admet-698	293	1	9	9	NUM
admet-698	293	2	(	(	PUNCT
admet-698	293	3	2008	2008	NUM
admet-698	293	4	)	)	PUNCT
admet-698	293	5	869	869	NUM
admet-698	293	6	-	-	SYM
admet-698	293	7	878	878	NUM
admet-698	293	8	.	.	PUNCT
admet-698	294	1	[	[	X
admet-698	294	2	23	23	NUM
admet-698	294	3	]	]	X
admet-698	294	4	k.	k.	PROPN
admet-698	294	5	etherson	etherson	PROPN
admet-698	294	6	,	,	PUNCT
admet-698	294	7	g.	g.	PROPN
admet-698	294	8	halbert	halbert	PROPN
admet-698	294	9	,	,	PUNCT
admet-698	294	10	m.	m.	PROPN
admet-698	294	11	elliott	elliott	PROPN
admet-698	294	12	.	.	PUNCT
admet-698	295	1	determination	determination	NOUN
admet-698	295	2	of	of	ADP
admet-698	295	3	excipient	excipient	NOUN
admet-698	295	4	based	base	VERB
admet-698	295	5	solubility	solubility	NOUN
admet-698	295	6	increases	increase	VERB
admet-698	295	7	using	use	VERB
admet-698	295	8	the	the	DET
admet-698	295	9	cheqsol	cheqsol	ADJ
admet-698	295	10	method	method	NOUN
admet-698	295	11	.	.	PUNCT
admet-698	296	1	int	int	NOUN
admet-698	296	2	.	.	PUNCT
admet-698	297	1	j.	j.	PROPN
admet-698	297	2	pharm	pharm	PROPN
admet-698	297	3	.	.	PUNCT
admet-698	298	1	465	465	NUM
admet-698	298	2	(	(	PUNCT
admet-698	298	3	2014	2014	NUM
admet-698	298	4	)	)	PUNCT
admet-698	298	5	202	202	NUM
admet-698	298	6	-	-	SYM
admet-698	298	7	209	209	NUM
admet-698	298	8	.	.	PUNCT
admet-698	299	1	[	[	X
admet-698	299	2	24	24	NUM
admet-698	299	3	]	]	X
admet-698	299	4	e.	e.	PROPN
admet-698	299	5	fornells	fornells	PROPN
admet-698	299	6	,	,	PUNCT
admet-698	299	7	e.	e.	PROPN
admet-698	299	8	fuguet	fuguet	PROPN
admet-698	299	9	,	,	PUNCT
admet-698	299	10	m.	m.	NOUN
admet-698	299	11	mañéa	mañéa	PROPN
admet-698	299	12	,	,	PUNCT
admet-698	299	13	r.	r.	PROPN
admet-698	299	14	ruiz	ruiz	PROPN
admet-698	299	15	,	,	PUNCT
admet-698	299	16	k.	k.	PROPN
admet-698	299	17	box	box	PROPN
admet-698	299	18	,	,	PUNCT
admet-698	299	19	e.	e.	PROPN
admet-698	299	20	bosch	bosch	PROPN
admet-698	299	21	,	,	PUNCT
admet-698	299	22	c.	c.	PROPN
admet-698	299	23	ràfols	ràfol	NOUN
admet-698	299	24	.	.	PUNCT
admet-698	300	1	effect	effect	NOUN
admet-698	300	2	of	of	ADP
admet-698	300	3	vinylpyrrolidone	vinylpyrrolidone	NOUN
admet-698	300	4	polymers	polymer	NOUN
admet-698	300	5	on	on	ADP
admet-698	300	6	the	the	DET
admet-698	300	7	solubility	solubility	NOUN
admet-698	300	8	and	and	CCONJ
admet-698	300	9	supersaturation	supersaturation	NOUN
admet-698	300	10	of	of	ADP
admet-698	300	11	drugs	drug	NOUN
admet-698	300	12	;	;	PUNCT
admet-698	300	13	a	a	DET
admet-698	300	14	study	study	NOUN
admet-698	300	15	using	use	VERB
admet-698	300	16	the	the	DET
admet-698	300	17	cheqsol	cheqsol	ADJ
admet-698	300	18	method	method	NOUN
admet-698	300	19	.	.	PUNCT
admet-698	301	1	eur	eur	PROPN
admet-698	301	2	.	.	PUNCT
admet-698	302	1	j.	j.	PROPN
admet-698	302	2	pharm	pharm	PROPN
admet-698	302	3	.	.	PUNCT
admet-698	303	1	sci	sci	PROPN
admet-698	303	2	.	.	PROPN
admet-698	304	1	117	117	NUM
admet-698	304	2	(	(	PUNCT
admet-698	304	3	2018	2018	NUM
admet-698	304	4	)	)	PUNCT
admet-698	304	5	227	227	NUM
admet-698	304	6	-	-	SYM
admet-698	304	7	235	235	NUM
admet-698	304	8	.	.	PUNCT
admet-698	305	1	[	[	X
admet-698	305	2	25	25	NUM
admet-698	305	3	]	]	PUNCT
admet-698	305	4	y.-l	y.-l	NOUN
admet-698	305	5	.	.	PUNCT
admet-698	306	1	hsieh	hsieh	PROPN
admet-698	306	2	,	,	PUNCT
admet-698	306	3	g.a	g.a	PROPN
admet-698	306	4	.	.	PROPN
admet-698	306	5	ilevbare	ilevbare	PROPN
admet-698	306	6	,	,	PUNCT
admet-698	306	7	b.	b.	PROPN
admet-698	306	8	van	van	PROPN
admet-698	306	9	eerdenbrugh	eerdenbrugh	PROPN
admet-698	306	10	,	,	PUNCT
admet-698	306	11	k.j	k.j	PROPN
admet-698	306	12	.	.	PROPN
admet-698	306	13	box	box	PROPN
admet-698	306	14	,	,	PUNCT
admet-698	306	15	m.v	m.v	PROPN
admet-698	306	16	.	.	PROPN
admet-698	306	17	sanchez	sanchez	PROPN
admet-698	306	18	-	-	PUNCT
admet-698	306	19	felix	felix	PROPN
admet-698	306	20	,	,	PUNCT
admet-698	306	21	l.s	l.s	PROPN
admet-698	306	22	.	.	PROPN
admet-698	306	23	taylor	taylor	PROPN
admet-698	306	24	.	.	PUNCT
admet-698	307	1	ph	ph	VERB
admet-698	307	2	-	-	ADJ
admet-698	307	3	induced	induced	ADJ
admet-698	307	4	precipitation	precipitation	NOUN
admet-698	307	5	behavior	behavior	NOUN
admet-698	307	6	of	of	ADP
admet-698	307	7	weakly	weakly	ADJ
admet-698	307	8	basic	basic	ADJ
admet-698	307	9	compounds	compound	NOUN
admet-698	307	10	:	:	PUNCT
admet-698	307	11	determination	determination	NOUN
admet-698	307	12	of	of	ADP
admet-698	307	13	extent	extent	NOUN
admet-698	307	14	and	and	CCONJ
admet-698	307	15	duration	duration	NOUN
admet-698	307	16	of	of	ADP
admet-698	307	17	supersaturation	supersaturation	NOUN
admet-698	307	18	using	use	VERB
admet-698	307	19	potentiometric	potentiometric	ADJ
admet-698	307	20	titration	titration	NOUN
admet-698	307	21	and	and	CCONJ
admet-698	307	22	correlation	correlation	NOUN
admet-698	307	23	to	to	ADP
admet-698	307	24	solid	solid	ADJ
admet-698	307	25	state	state	NOUN
admet-698	307	26	properties	property	NOUN
admet-698	307	27	.	.	PUNCT
admet-698	308	1	pharm	pharm	NOUN
admet-698	308	2	.	.	PUNCT
admet-698	309	1	res	re	NOUN
admet-698	309	2	.	.	PROPN
admet-698	310	1	29	29	NUM
admet-698	310	2	(	(	PUNCT
admet-698	310	3	2012	2012	NUM
admet-698	310	4	)	)	PUNCT
admet-698	310	5	2738	2738	NUM
admet-698	310	6	-	-	SYM
admet-698	310	7	2753	2753	NUM
admet-698	310	8	.	.	PUNCT
admet-698	311	1	[	[	X
admet-698	311	2	26	26	NUM
admet-698	311	3	]	]	PUNCT
admet-698	311	4	a.	a.	NOUN
admet-698	311	5	llinàs	llinàs	PROPN
admet-698	311	6	,	,	PUNCT
admet-698	311	7	j.c	j.c	PROPN
admet-698	311	8	.	.	PROPN
admet-698	311	9	burley	burley	PROPN
admet-698	311	10	,	,	PUNCT
admet-698	311	11	k.j	k.j	PROPN
admet-698	311	12	.	.	PROPN
admet-698	311	13	box	box	PROPN
admet-698	311	14	,	,	PUNCT
admet-698	311	15	r.c	r.c	PROPN
admet-698	311	16	.	.	PROPN
admet-698	311	17	glen	glen	PROPN
admet-698	311	18	,	,	PUNCT
admet-698	311	19	j.m	j.m	PROPN
admet-698	311	20	.	.	PROPN
admet-698	311	21	goodman	goodman	PROPN
admet-698	311	22	.	.	PUNCT
admet-698	312	1	diclofenac	diclofenac	PROPN
admet-698	312	2	solubility	solubility	NOUN
admet-698	312	3	:	:	PUNCT
admet-698	312	4	independent	independent	ADJ
admet-698	312	5	determination	determination	NOUN
admet-698	312	6	of	of	ADP
admet-698	312	7	the	the	DET
admet-698	312	8	intrinsic	intrinsic	ADJ
admet-698	312	9	solubility	solubility	NOUN
admet-698	312	10	of	of	ADP
admet-698	312	11	three	three	NUM
admet-698	312	12	crystal	crystal	NOUN
admet-698	312	13	forms	form	NOUN
admet-698	312	14	.	.	PUNCT
admet-698	313	1	j.	j.	PROPN
admet-698	313	2	med	med	PROPN
admet-698	313	3	.	.	PROPN
admet-698	313	4	chem	chem	PROPN
admet-698	313	5	.	.	PUNCT
admet-698	314	1	50	50	NUM
admet-698	314	2	(	(	PUNCT
admet-698	314	3	2007	2007	NUM
admet-698	314	4	)	)	PUNCT
admet-698	314	5	979	979	NUM
admet-698	314	6	-	-	SYM
admet-698	314	7	983	983	NUM
admet-698	314	8	.	.	PUNCT
admet-698	315	1	[	[	X
admet-698	315	2	27	27	NUM
admet-698	315	3	]	]	X
admet-698	315	4	l.y.s	l.y.s	PROPN
admet-698	315	5	.	.	PUNCT
admet-698	316	1	narasimham	narasimham	PROPN
admet-698	316	2	,	,	PUNCT
admet-698	316	3	v.d	v.d	PROPN
admet-698	316	4	.	.	PROPN
admet-698	316	5	barhate	barhate	PROPN
admet-698	316	6	.	.	PUNCT
admet-698	317	1	kinetic	kinetic	ADJ
admet-698	317	2	and	and	CCONJ
admet-698	317	3	intrinsic	intrinsic	ADJ
admet-698	317	4	solubility	solubility	NOUN
admet-698	317	5	determination	determination	NOUN
admet-698	317	6	of	of	ADP
admet-698	317	7	some	some	DET
admet-698	317	8	β	β	NOUN
admet-698	317	9	-	-	NOUN
admet-698	317	10	blockers	blocker	NOUN
admet-698	317	11	and	and	CCONJ
admet-698	317	12	antidiabetics	antidiabetic	NOUN
admet-698	317	13	by	by	ADP
admet-698	317	14	potentiometry	potentiometry	PROPN
admet-698	317	15	.	.	PUNCT
admet-698	318	1	j.	j.	PROPN
admet-698	318	2	pharmacy	pharmacy	PROPN
admet-698	318	3	res	re	NOUN
admet-698	318	4	.	.	PROPN
admet-698	318	5	4	4	NUM
admet-698	318	6	(	(	PUNCT
admet-698	318	7	2011	2011	NUM
admet-698	318	8	)	)	PUNCT
admet-698	318	9	532	532	NUM
admet-698	318	10	-	-	SYM
admet-698	318	11	536	536	NUM
admet-698	318	12	.	.	PUNCT
admet-698	319	1	[	[	X
admet-698	319	2	28	28	NUM
admet-698	319	3	]	]	X
admet-698	319	4	d.	d.	PROPN
admet-698	319	5	schönherr	schönherr	PROPN
admet-698	319	6	,	,	PUNCT
admet-698	319	7	u.	u.	PROPN
admet-698	319	8	wollatz	wollatz	PROPN
admet-698	319	9	,	,	PUNCT
admet-698	319	10	d.	d.	PROPN
admet-698	319	11	haznar	haznar	PROPN
admet-698	319	12	-	-	PUNCT
admet-698	319	13	garbacz	garbacz	NOUN
admet-698	319	14	,	,	PUNCT
admet-698	319	15	u.	u.	PROPN
admet-698	319	16	hanke	hanke	PROPN
admet-698	319	17	,	,	PUNCT
admet-698	319	18	k.j	k.j	PROPN
admet-698	319	19	.	.	PROPN
admet-698	319	20	box	box	PROPN
admet-698	319	21	,	,	PUNCT
admet-698	319	22	r.	r.	PROPN
admet-698	319	23	taylor	taylor	PROPN
admet-698	319	24	,	,	PUNCT
admet-698	319	25	r.	r.	PROPN
admet-698	319	26	ruiz	ruiz	PROPN
admet-698	319	27	,	,	PUNCT
admet-698	319	28	s.	s.	PROPN
admet-698	319	29	beato	beato	PROPN
admet-698	319	30	,	,	PUNCT
admet-698	319	31	d.	d.	PROPN
admet-698	319	32	becker	becker	PROPN
admet-698	319	33	,	,	PUNCT
admet-698	319	34	w.	w.	PROPN
admet-698	319	35	weitschies	weitschie	NOUN
admet-698	319	36	.	.	PUNCT
admet-698	320	1	characterisation	characterisation	NOUN
admet-698	320	2	of	of	ADP
admet-698	320	3	selected	select	VERB
admet-698	320	4	active	active	ADJ
admet-698	320	5	agents	agent	NOUN
admet-698	320	6	regarding	regard	VERB
admet-698	320	7	pka	pka	PROPN
admet-698	320	8	values	value	NOUN
admet-698	320	9	,	,	PUNCT
admet-698	320	10	solubility	solubility	NOUN
admet-698	320	11	concentrations	concentration	NOUN
admet-698	320	12	and	and	CCONJ
admet-698	320	13	ph	ph	ADJ
admet-698	320	14	profiles	profile	NOUN
admet-698	320	15	by	by	ADP
admet-698	320	16	siriust3	siriust3	PROPN
admet-698	320	17	.	.	PUNCT
admet-698	321	1	eur	eur	PROPN
admet-698	321	2	.	.	PUNCT
admet-698	322	1	j.	j.	PROPN
admet-698	322	2	pharm	pharm	PROPN
admet-698	322	3	.	.	PUNCT
admet-698	323	1	biopharm	biopharm	PROPN
admet-698	323	2	.	.	PUNCT
admet-698	324	1	92	92	NUM
admet-698	324	2	(	(	PUNCT
admet-698	324	3	2015	2015	NUM
admet-698	324	4	)	)	PUNCT
admet-698	324	5	155	155	NUM
admet-698	324	6	-	-	SYM
admet-698	324	7	170	170	NUM
admet-698	324	8	.	.	PUNCT
admet-698	325	1	[	[	X
admet-698	325	2	29	29	NUM
admet-698	325	3	]	]	X
admet-698	325	4	c.	c.	NOUN
admet-698	325	5	sköld	sköld	NOUN
admet-698	325	6	,	,	PUNCT
admet-698	325	7	s.	s.	PROPN
admet-698	325	8	winiwarter	winiwarter	PROPN
admet-698	325	9	,	,	PUNCT
admet-698	325	10	j.	j.	PROPN
admet-698	325	11	wernevik	wernevik	PROPN
admet-698	325	12	,	,	PUNCT
admet-698	325	13	f.	f.	PROPN
admet-698	325	14	bergström	bergström	PROPN
admet-698	325	15	,	,	PUNCT
admet-698	325	16	l.	l.	PROPN
admet-698	325	17	engström	engström	PROPN
admet-698	325	18	,	,	PUNCT
admet-698	325	19	r.	r.	PROPN
admet-698	325	20	allen	allen	PROPN
admet-698	325	21	,	,	PUNCT
admet-698	325	22	k.	k.	PROPN
admet-698	325	23	box	box	PROPN
admet-698	325	24	,	,	PUNCT
admet-698	325	25	j.	j.	PROPN
admet-698	325	26	comer	comer	PROPN
admet-698	325	27	,	,	PUNCT
admet-698	325	28	j.	j.	PROPN
admet-698	325	29	mole	mole	PROPN
admet-698	325	30	,	,	PUNCT
admet-698	325	31	a.	a.	PROPN
admet-698	325	32	hallberg	hallberg	PROPN
admet-698	325	33	,	,	PUNCT
admet-698	325	34	h.	h.	PROPN
admet-698	325	35	lennernäs	lennernäs	PROPN
admet-698	325	36	,	,	PUNCT
admet-698	325	37	t.	t.	PROPN
admet-698	325	38	lundstedt	lundstedt	PROPN
admet-698	325	39	,	,	PUNCT
admet-698	325	40	a.-l	a.-l	PROPN
admet-698	325	41	.	.	PUNCT
admet-698	326	1	ungell	ungell	PROPN
admet-698	326	2	,	,	PUNCT
admet-698	326	3	a.	a.	NOUN
admet-698	326	4	karlén	karlén	PROPN
admet-698	326	5	.	.	PUNCT
admet-698	327	1	presentation	presentation	NOUN
admet-698	327	2	of	of	ADP
admet-698	327	3	a	a	DET
admet-698	327	4	structurally	structurally	ADV
admet-698	327	5	diverse	diverse	ADJ
admet-698	327	6	and	and	CCONJ
admet-698	327	7	commercially	commercially	ADV
admet-698	327	8	available	available	ADJ
admet-698	327	9	drug	drug	NOUN
admet-698	327	10	data	datum	NOUN
admet-698	327	11	set	set	VERB
admet-698	327	12	for	for	ADP
admet-698	327	13	correlation	correlation	NOUN
admet-698	327	14	and	and	CCONJ
admet-698	327	15	benchmarking	benchmarke	VERB
admet-698	327	16	studies	study	NOUN
admet-698	327	17	.	.	PUNCT
admet-698	328	1	j.	j.	PROPN
admet-698	328	2	med	med	PROPN
admet-698	328	3	.	.	PROPN
admet-698	328	4	chem	chem	PROPN
admet-698	328	5	.	.	PUNCT
admet-698	329	1	49	49	NUM
admet-698	329	2	(	(	PUNCT
admet-698	329	3	2006	2006	NUM
admet-698	329	4	)	)	PUNCT
admet-698	329	5	6660	6660	NUM
admet-698	329	6	-	-	SYM
admet-698	329	7	6671	6671	NUM
admet-698	329	8	.	.	PUNCT
admet-698	330	1	[	[	X
admet-698	330	2	30	30	NUM
admet-698	330	3	]	]	X
admet-698	330	4	j.	j.	PROPN
admet-698	330	5	comer	comer	PROPN
admet-698	330	6	,	,	PUNCT
admet-698	330	7	s.	s.	PROPN
admet-698	330	8	judge	judge	PROPN
admet-698	330	9	,	,	PUNCT
admet-698	330	10	d.	d.	PROPN
admet-698	330	11	matthews	matthews	PROPN
admet-698	330	12	,	,	PUNCT
admet-698	330	13	l.	l.	PROPN
admet-698	330	14	towes	towes	PROPN
admet-698	330	15	,	,	PUNCT
admet-698	330	16	b.	b.	PROPN
admet-698	330	17	falcone	falcone	PROPN
admet-698	330	18	,	,	PUNCT
admet-698	330	19	j.	j.	PROPN
admet-698	330	20	goodman	goodman	PROPN
admet-698	330	21	,	,	PUNCT
admet-698	330	22	j.	j.	PROPN
admet-698	330	23	dearden	dearden	PROPN
admet-698	330	24	.	.	PUNCT
admet-698	331	1	the	the	DET
admet-698	331	2	intrinsic	intrinsic	ADJ
admet-698	331	3	aqueous	aqueous	ADJ
admet-698	331	4	solubility	solubility	NOUN
admet-698	331	5	of	of	ADP
admet-698	331	6	indomethacin	indomethacin	PROPN
admet-698	331	7	.	.	PUNCT
admet-698	332	1	admet	admet	PROPN
admet-698	332	2	&	&	CCONJ
admet-698	332	3	dmpk	dmpk	PROPN
admet-698	332	4	2	2	NUM
admet-698	332	5	(	(	PUNCT
admet-698	332	6	2014	2014	NUM
admet-698	332	7	)	)	PUNCT
admet-698	332	8	18	18	NUM
admet-698	332	9	-	-	SYM
admet-698	332	10	32	32	NUM
admet-698	332	11	.	.	PUNCT
admet-698	333	1	[	[	X
admet-698	333	2	31	31	NUM
admet-698	333	3	]	]	PUNCT
admet-698	333	4	c.a.s	c.a.s	PROPN
admet-698	333	5	.	.	PROPN
admet-698	333	6	bergström	bergström	PROPN
admet-698	333	7	,	,	PUNCT
admet-698	333	8	m	m	PROPN
admet-698	333	9	strafford	strafford	PROPN
admet-698	333	10	,	,	PUNCT
admet-698	333	11	l.	l.	PROPN
admet-698	333	12	lazarova	lazarova	PROPN
admet-698	333	13	,	,	PUNCT
admet-698	333	14	a.	a.	NOUN
admet-698	333	15	avdeef	avdeef	PROPN
admet-698	333	16	,	,	PUNCT
admet-698	333	17	k.	k.	PROPN
admet-698	333	18	luthman	luthman	PROPN
admet-698	333	19	,	,	PUNCT
admet-698	333	20	p.	p.	PROPN
admet-698	333	21	artursson	artursson	PROPN
admet-698	333	22	.	.	PUNCT
admet-698	334	1	absorption	absorption	NOUN
admet-698	334	2	classification	classification	NOUN
admet-698	334	3	of	of	ADP
admet-698	334	4	oral	oral	ADJ
admet-698	334	5	drugs	drug	NOUN
admet-698	334	6	based	base	VERB
admet-698	334	7	on	on	ADP
admet-698	334	8	molecular	molecular	ADJ
admet-698	334	9	surface	surface	NOUN
admet-698	334	10	properties	property	NOUN
admet-698	334	11	.	.	PUNCT
admet-698	335	1	j.	j.	PROPN
admet-698	335	2	med	med	PROPN
admet-698	335	3	.	.	PROPN
admet-698	335	4	chem	chem	PROPN
admet-698	335	5	.	.	PUNCT
admet-698	336	1	46	46	NUM
admet-698	336	2	(	(	PUNCT
admet-698	336	3	2003	2003	NUM
admet-698	336	4	)	)	PUNCT
admet-698	336	5	558	558	NUM
admet-698	336	6	-	-	SYM
admet-698	336	7	570	570	NUM
admet-698	336	8	.	.	PUNCT
admet-698	337	1	[	[	X
admet-698	337	2	32	32	NUM
admet-698	337	3	]	]	X
admet-698	337	4	k.j	k.j	PROPN
admet-698	337	5	.	.	PROPN
admet-698	337	6	box	box	PROPN
admet-698	337	7	,	,	PUNCT
admet-698	337	8	g.	g.	PROPN
admet-698	337	9	völgyi	völgyi	PROPN
admet-698	337	10	,	,	PUNCT
admet-698	337	11	e.	e.	PROPN
admet-698	337	12	baka	baka	PROPN
admet-698	337	13	,	,	PUNCT
admet-698	337	14	m.	m.	PROPN
admet-698	337	15	stuart	stuart	PROPN
admet-698	337	16	,	,	PUNCT
admet-698	338	1	k.	k.	PROPN
admet-698	338	2	takács	takács	PROPN
admet-698	338	3	-	-	PUNCT
admet-698	338	4	novák	novák	NOUN
admet-698	338	5	,	,	PUNCT
admet-698	338	6	j.e.a	j.e.a	ADJ
admet-698	338	7	.	.	PUNCT
admet-698	338	8	comer	comer	PROPN
admet-698	338	9	.	.	PUNCT
admet-698	339	1	equilibrium	equilibrium	NOUN
admet-698	339	2	versus	versus	ADP
admet-698	339	3	kinetic	kinetic	ADJ
admet-698	339	4	measurements	measurement	NOUN
admet-698	339	5	of	of	ADP
admet-698	339	6	aqueous	aqueous	ADJ
admet-698	339	7	solubility	solubility	NOUN
admet-698	339	8	,	,	PUNCT
admet-698	339	9	and	and	CCONJ
admet-698	339	10	the	the	DET
admet-698	339	11	ability	ability	NOUN
admet-698	339	12	of	of	ADP
admet-698	339	13	compounds	compound	NOUN
admet-698	339	14	to	to	PART
admet-698	339	15	supersaturate	supersaturate	VERB
admet-698	339	16	in	in	ADP
admet-698	339	17	solutiona	solutiona	PROPN
admet-698	339	18	validation	validation	PROPN
admet-698	339	19	study	study	NOUN
admet-698	339	20	.	.	PUNCT
admet-698	340	1	j.	j.	PROPN
admet-698	340	2	pharm	pharm	PROPN
admet-698	340	3	.	.	PUNCT
admet-698	341	1	sci	sci	PROPN
admet-698	341	2	.	.	PROPN
admet-698	342	1	95	95	NUM
admet-698	342	2	(	(	PUNCT
admet-698	342	3	2006	2006	NUM
admet-698	342	4	)	)	PUNCT
admet-698	342	5	1298	1298	NUM
admet-698	342	6	-	-	SYM
admet-698	342	7	1307	1307	NUM
admet-698	342	8	.	.	PUNCT
admet-698	343	1	©	©	PROPN
admet-698	343	2	2019	2019	NUM
admet-698	343	3	by	by	ADP
admet-698	343	4	the	the	DET
admet-698	343	5	authors	author	NOUN
admet-698	343	6	;	;	PUNCT
admet-698	343	7	licensee	licensee	PROPN
admet-698	343	8	iapc	iapc	PROPN
admet-698	343	9	,	,	PUNCT
admet-698	343	10	zagreb	zagreb	PROPN
admet-698	343	11	,	,	PUNCT
admet-698	343	12	croatia	croatia	PROPN
admet-698	343	13	.	.	PUNCT
admet-698	344	1	this	this	DET
admet-698	344	2	article	article	NOUN
admet-698	344	3	is	be	AUX
admet-698	344	4	an	an	DET
admet-698	344	5	open	open	ADJ
admet-698	344	6	-	-	PUNCT
admet-698	344	7	access	access	NOUN
admet-698	344	8	article	article	NOUN
admet-698	344	9	distributed	distribute	VERB
admet-698	344	10	under	under	ADP
admet-698	344	11	the	the	DET
admet-698	344	12	terms	term	NOUN
admet-698	344	13	and	and	CCONJ
admet-698	344	14	conditions	condition	NOUN
admet-698	344	15	of	of	ADP
admet-698	344	16	the	the	DET
admet-698	344	17	creative	creative	ADJ
admet-698	344	18	commons	common	NOUN
admet-698	344	19	attribution	attribution	NOUN
admet-698	344	20	license	license	NOUN
admet-698	344	21	(	(	PUNCT
admet-698	344	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-698	344	23	)	)	PUNCT
admet-698	344	24	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN