id	sid	tid	token	lemma	pos
admet-801	1	1	in	in	ADP
admet-801	1	2	vitro	vitro	X
admet-801	1	3	release	release	NOUN
admet-801	1	4	studies	study	NOUN
admet-801	1	5	of	of	ADP
admet-801	1	6	furosemide	furosemide	ADJ
admet-801	1	7	reference	reference	NOUN
admet-801	1	8	tablets	tablet	NOUN
admet-801	1	9	:	:	PUNCT
admet-801	1	10	influence	influence	NOUN
admet-801	1	11	of	of	ADP
admet-801	1	12	agitation	agitation	NOUN
admet-801	1	13	rate	rate	NOUN
admet-801	1	14	,	,	PUNCT
admet-801	1	15	usp	usp	NOUN
admet-801	1	16	apparatus	apparatus	NOUN
admet-801	1	17	,	,	PUNCT
admet-801	1	18	and	and	CCONJ
admet-801	1	19	dissolution	dissolution	ADJ
admet-801	1	20	media	medium	NOUN
admet-801	1	21	doi	doi	NOUN
admet-801	1	22	:	:	PUNCT
admet-801	1	23	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	PROPN
admet-801	1	24	411	411	NUM
admet-801	1	25	admet	admet	PROPN
admet-801	1	26	&	&	CCONJ
admet-801	1	27	dmpk	dmpk	PROPN
admet-801	1	28	8(4	8(4	NOUN
admet-801	1	29	)	)	PUNCT
admet-801	1	30	(	(	PUNCT
admet-801	1	31	2020	2020	NUM
admet-801	1	32	)	)	PUNCT
admet-801	1	33	411	411	NUM
admet-801	1	34	-	-	SYM
admet-801	1	35	423	423	NUM
admet-801	1	36	;	;	PUNCT
admet-801	1	37	doi	doi	NOUN
admet-801	1	38	:	:	PUNCT
admet-801	1	39	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	X
admet-801	1	40	open	open	ADJ
admet-801	1	41	access	access	NOUN
admet-801	1	42	:	:	PUNCT
admet-801	1	43	issn	issn	PROPN
admet-801	1	44	:	:	PUNCT
admet-801	1	45	1848	1848	NUM
admet-801	1	46	-	-	SYM
admet-801	1	47	7718	7718	NUM
admet-801	1	48	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-801	1	49	original	original	ADJ
admet-801	1	50	scientific	scientific	ADJ
admet-801	1	51	paper	paper	NOUN
admet-801	1	52	in	in	ADP
admet-801	1	53	vitro	vitro	X
admet-801	1	54	release	release	NOUN
admet-801	1	55	studies	study	NOUN
admet-801	1	56	of	of	ADP
admet-801	1	57	furosemide	furosemide	ADJ
admet-801	1	58	reference	reference	NOUN
admet-801	1	59	tablets	tablet	NOUN
admet-801	1	60	:	:	PUNCT
admet-801	1	61	influence	influence	NOUN
admet-801	1	62	of	of	ADP
admet-801	1	63	agitation	agitation	NOUN
admet-801	1	64	rate	rate	NOUN
admet-801	1	65	,	,	PUNCT
admet-801	1	66	usp	usp	NOUN
admet-801	1	67	apparatus	apparatus	NOUN
admet-801	1	68	,	,	PUNCT
admet-801	1	69	and	and	CCONJ
admet-801	1	70	dissolution	dissolution	ADJ
admet-801	1	71	media	medium	NOUN
admet-801	1	72	raúl	raúl	NOUN
admet-801	1	73	medina	medina	PROPN
admet-801	1	74	-	-	PUNCT
admet-801	1	75	lópez	lópez	PROPN
admet-801	1	76	*	*	PUNCT
admet-801	1	77	,	,	PUNCT
admet-801	1	78	sergio	sergio	PROPN
admet-801	1	79	guillén	guillén	PROPN
admet-801	1	80	-	-	PUNCT
admet-801	1	81	moedano	moedano	ADJ
admet-801	1	82	and	and	CCONJ
admet-801	1	83	marcela	marcela	PROPN
admet-801	1	84	hurtado	hurtado	PROPN
admet-801	1	85	departamento	departamento	PROPN
admet-801	1	86	sistemas	sistemas	PROPN
admet-801	1	87	biológicos	biológicos	PROPN
admet-801	1	88	,	,	PUNCT
admet-801	1	89	universidad	universidad	PROPN
admet-801	1	90	autónoma	autónoma	PROPN
admet-801	1	91	metropolitana	metropolitana	PROPN
admet-801	1	92	-	-	PUNCT
admet-801	1	93	xochimilco	xochimilco	PROPN
admet-801	1	94	,	,	PUNCT
admet-801	1	95	mexico	mexico	PROPN
admet-801	1	96	city	city	PROPN
admet-801	1	97	,	,	PUNCT
admet-801	1	98	mexico	mexico	PROPN
admet-801	1	99	*	*	PUNCT
admet-801	1	100	corresponding	correspond	VERB
admet-801	1	101	author	author	NOUN
admet-801	1	102	:	:	PUNCT
admet-801	1	103	e	e	NOUN
admet-801	1	104	-	-	NOUN
admet-801	1	105	mail	mail	NOUN
admet-801	1	106	:	:	PUNCT
admet-801	1	107	rmlopez@correo.xoc.uam.mx	rmlopez@correo.xoc.uam.mx	X
admet-801	1	108	;	;	PUNCT
admet-801	1	109	tel	tel	PROPN
admet-801	1	110	.	.	PUNCT
admet-801	1	111	:	:	PUNCT
admet-801	2	1	+	+	CCONJ
admet-801	2	2	52	52	NUM
admet-801	2	3	55	55	NUM
admet-801	2	4	54837000	54837000	NUM
admet-801	2	5	ext	ext	NOUN
admet-801	2	6	.	.	PUNCT
admet-801	3	1	3445	3445	NUM
admet-801	3	2	;	;	PUNCT
admet-801	3	3	fax	fax	NOUN
admet-801	3	4	:	:	PUNCT
admet-801	3	5	+	+	NUM
admet-801	3	6	52	52	NUM
admet-801	3	7	55	55	NUM
admet-801	3	8	55947929	55947929	NUM
admet-801	3	9	received	receive	VERB
admet-801	3	10	:	:	PUNCT
admet-801	3	11	march	march	PROPN
admet-801	3	12	06	06	NUM
admet-801	3	13	,	,	PUNCT
admet-801	3	14	2020	2020	NUM
admet-801	3	15	;	;	PUNCT
admet-801	3	16	revised	revise	VERB
admet-801	3	17	:	:	PUNCT
admet-801	3	18	june	june	PROPN
admet-801	3	19	20	20	NUM
admet-801	3	20	,	,	PUNCT
admet-801	3	21	2020	2020	NUM
admet-801	3	22	;	;	PUNCT
admet-801	3	23	published	publish	VERB
admet-801	3	24	:	:	PUNCT
admet-801	3	25	june	june	PROPN
admet-801	3	26	29	29	NUM
admet-801	3	27	,	,	PUNCT
admet-801	3	28	2020	2020	NUM
admet-801	3	29	abstract	abstract	ADJ
admet-801	3	30	furosemide	furosemide	NOUN
admet-801	3	31	is	be	AUX
admet-801	3	32	a	a	DET
admet-801	3	33	diuretic	diuretic	ADJ
admet-801	3	34	drug	drug	NOUN
admet-801	3	35	widely	widely	ADV
admet-801	3	36	used	use	VERB
admet-801	3	37	in	in	ADP
admet-801	3	38	chronic	chronic	ADJ
admet-801	3	39	renal	renal	ADJ
admet-801	3	40	failure	failure	NOUN
admet-801	3	41	.	.	PUNCT
admet-801	4	1	the	the	DET
admet-801	4	2	drug	drug	NOUN
admet-801	4	3	has	have	VERB
admet-801	4	4	low	low	ADJ
admet-801	4	5	solubility	solubility	NOUN
admet-801	4	6	and	and	CCONJ
admet-801	4	7	permeability	permeability	NOUN
admet-801	4	8	,	,	PUNCT
admet-801	4	9	which	which	PRON
admet-801	4	10	cause	cause	VERB
admet-801	4	11	clinical	clinical	ADJ
admet-801	4	12	problems	problem	NOUN
admet-801	4	13	.	.	PUNCT
admet-801	5	1	studying	study	VERB
admet-801	5	2	the	the	DET
admet-801	5	3	in	in	ADV
admet-801	5	4	vitro	vitro	X
admet-801	5	5	release	release	NOUN
admet-801	5	6	performance	performance	NOUN
admet-801	5	7	elucidates	elucidate	VERB
admet-801	5	8	the	the	DET
admet-801	5	9	rate	rate	NOUN
admet-801	5	10	and	and	CCONJ
admet-801	5	11	extent	extent	NOUN
admet-801	5	12	of	of	ADP
admet-801	5	13	drug	drug	NOUN
admet-801	5	14	dissolved	dissolve	VERB
admet-801	5	15	from	from	ADP
admet-801	5	16	dosage	dosage	NOUN
admet-801	5	17	forms	form	NOUN
admet-801	5	18	under	under	ADP
admet-801	5	19	different	different	ADJ
admet-801	5	20	conditions	condition	NOUN
admet-801	5	21	.	.	PUNCT
admet-801	6	1	furosemide	furosemide	ADJ
admet-801	6	2	reference	reference	NOUN
admet-801	6	3	tablets	tablet	NOUN
admet-801	6	4	were	be	AUX
admet-801	6	5	tested	test	VERB
admet-801	6	6	using	use	VERB
admet-801	6	7	usp	usp	NOUN
admet-801	6	8	apparatuses	apparatus	NOUN
admet-801	6	9	1	1	NUM
admet-801	6	10	and	and	CCONJ
admet-801	6	11	2	2	NUM
admet-801	6	12	as	as	ADV
admet-801	6	13	well	well	ADV
admet-801	6	14	as	as	ADP
admet-801	6	15	the	the	DET
admet-801	6	16	flow	flow	NOUN
admet-801	6	17	-	-	PUNCT
admet-801	6	18	through	through	ADP
admet-801	6	19	cell	cell	NOUN
admet-801	6	20	method	method	NOUN
admet-801	6	21	(	(	PUNCT
admet-801	6	22	usp	usp	NOUN
admet-801	6	23	apparatus	apparatus	NOUN
admet-801	6	24	4	4	NUM
admet-801	6	25	)	)	PUNCT
admet-801	6	26	,	,	PUNCT
admet-801	6	27	a	a	DET
admet-801	6	28	dissolution	dissolution	NOUN
admet-801	6	29	apparatus	apparatus	NOUN
admet-801	6	30	that	that	PRON
admet-801	6	31	simulates	simulate	VERB
admet-801	6	32	the	the	DET
admet-801	6	33	human	human	ADJ
admet-801	6	34	gastrointestinal	gastrointestinal	ADJ
admet-801	6	35	tract	tract	NOUN
admet-801	6	36	better	well	ADV
admet-801	6	37	than	than	ADP
admet-801	6	38	the	the	DET
admet-801	6	39	other	other	ADJ
admet-801	6	40	methods	method	NOUN
admet-801	6	41	.	.	PUNCT
admet-801	7	1	dissolution	dissolution	ADJ
admet-801	7	2	profiles	profile	NOUN
admet-801	7	3	were	be	AUX
admet-801	7	4	created	create	VERB
admet-801	7	5	with	with	ADP
admet-801	7	6	usp	usp	NOUN
admet-801	7	7	apparatuses	apparatus	NOUN
admet-801	7	8	1	1	NUM
admet-801	7	9	and	and	CCONJ
admet-801	7	10	2	2	NUM
admet-801	7	11	at	at	ADP
admet-801	7	12	25	25	NUM
admet-801	7	13	,	,	PUNCT
admet-801	7	14	50	50	NUM
admet-801	7	15	,	,	PUNCT
admet-801	7	16	and	and	CCONJ
admet-801	7	17	75	75	NUM
admet-801	7	18	rpm	rpm	NOUN
admet-801	7	19	and	and	CCONJ
admet-801	7	20	900	900	NUM
admet-801	7	21	ml	ml	NOUN
admet-801	7	22	of	of	ADP
admet-801	7	23	0.1	0.1	NUM
admet-801	7	24	m	m	PROPN
admet-801	7	25	hydrochloric	hydrochloric	ADJ
admet-801	7	26	acid	acid	NOUN
admet-801	7	27	,	,	PUNCT
admet-801	7	28	acetate	acetate	NOUN
admet-801	7	29	buffer	buffer	NOUN
admet-801	7	30	(	(	PUNCT
admet-801	7	31	ph	ph	NOUN
admet-801	7	32	4.5	4.5	NUM
admet-801	7	33	)	)	PUNCT
admet-801	7	34	,	,	PUNCT
admet-801	7	35	and	and	CCONJ
admet-801	7	36	phosphate	phosphate	ADJ
admet-801	7	37	buffer	buffer	NOUN
admet-801	7	38	(	(	PUNCT
admet-801	7	39	ph	ph	NOUN
admet-801	7	40	6.8	6.8	NUM
admet-801	7	41	)	)	PUNCT
admet-801	7	42	.	.	PUNCT
admet-801	8	1	usp	usp	PROPN
admet-801	8	2	apparatus	apparatus	NOUN
admet-801	8	3	4	4	NUM
admet-801	8	4	with	with	ADP
admet-801	8	5	a	a	DET
admet-801	8	6	laminar	laminar	ADJ
admet-801	8	7	flow	flow	NOUN
admet-801	8	8	of	of	ADP
admet-801	8	9	16	16	NUM
admet-801	8	10	ml	ml	NOUN
admet-801	8	11	/	/	SYM
admet-801	8	12	min	min	NOUN
admet-801	8	13	and	and	CCONJ
admet-801	8	14	22.6	22.6	NUM
admet-801	8	15	mm	mm	NOUN
admet-801	8	16	cells	cell	NOUN
admet-801	8	17	was	be	AUX
admet-801	8	18	used	use	VERB
admet-801	8	19	.	.	PUNCT
admet-801	9	1	drug	drug	NOUN
admet-801	9	2	dissolution	dissolution	PROPN
admet-801	9	3	was	be	AUX
admet-801	9	4	quantified	quantify	VERB
admet-801	9	5	at	at	ADP
admet-801	9	6	274	274	NUM
admet-801	9	7	nm	nm	NOUN
admet-801	9	8	for	for	ADP
admet-801	9	9	60	60	NUM
admet-801	9	10	min	min	NOUN
admet-801	9	11	.	.	PROPN
admet-801	9	12	mean	mean	PROPN
admet-801	9	13	dissolution	dissolution	ADJ
admet-801	9	14	time	time	NOUN
admet-801	9	15	,	,	PUNCT
admet-801	9	16	dissolution	dissolution	ADJ
admet-801	9	17	efficiency	efficiency	NOUN
admet-801	9	18	,	,	PUNCT
admet-801	9	19	time	time	NOUN
admet-801	9	20	to	to	ADP
admet-801	9	21	50	50	NUM
admet-801	9	22	%	%	NOUN
admet-801	9	23	dissolution	dissolution	NOUN
admet-801	9	24	,	,	PUNCT
admet-801	9	25	and	and	CCONJ
admet-801	9	26	time	time	NOUN
admet-801	9	27	to	to	ADP
admet-801	9	28	80	80	NUM
admet-801	9	29	%	%	NOUN
admet-801	9	30	dissolution	dissolution	NOUN
admet-801	9	31	data	datum	NOUN
admet-801	9	32	were	be	AUX
admet-801	9	33	used	use	VERB
admet-801	9	34	to	to	PART
admet-801	9	35	compare	compare	VERB
admet-801	9	36	dissolution	dissolution	ADJ
admet-801	9	37	profiles	profile	NOUN
admet-801	9	38	.	.	PUNCT
admet-801	10	1	additionally	additionally	ADV
admet-801	10	2	,	,	PUNCT
admet-801	10	3	zero	zero	NUM
admet-801	10	4	-	-	PUNCT
admet-801	10	5	order	order	NOUN
admet-801	10	6	,	,	PUNCT
admet-801	10	7	first	first	ADJ
admet-801	10	8	-	-	PUNCT
admet-801	10	9	order	order	NOUN
admet-801	10	10	,	,	PUNCT
admet-801	10	11	higuchi	higuchi	PROPN
admet-801	10	12	,	,	PUNCT
admet-801	10	13	hixson	hixson	PROPN
admet-801	10	14	-	-	PUNCT
admet-801	10	15	crowell	crowell	PROPN
admet-801	10	16	,	,	PUNCT
admet-801	10	17	makoid	makoid	NOUN
admet-801	10	18	-	-	PUNCT
admet-801	10	19	banakar	banakar	NOUN
admet-801	10	20	,	,	PUNCT
admet-801	10	21	and	and	CCONJ
admet-801	10	22	weibull	weibull	PROPN
admet-801	10	23	models	model	NOUN
admet-801	10	24	were	be	AUX
admet-801	10	25	used	use	VERB
admet-801	10	26	to	to	PART
admet-801	10	27	adjust	adjust	VERB
admet-801	10	28	furosemide	furosemide	ADJ
admet-801	10	29	dissolution	dissolution	PROPN
admet-801	10	30	data	datum	NOUN
admet-801	10	31	.	.	PUNCT
admet-801	11	1	between	between	ADP
admet-801	11	2	usp	usp	NOUN
admet-801	11	3	apparatus	apparatus	NOUN
admet-801	11	4	1	1	NUM
admet-801	11	5	and	and	CCONJ
admet-801	11	6	2	2	NUM
admet-801	11	7	,	,	PUNCT
admet-801	11	8	significant	significant	ADJ
admet-801	11	9	differences	difference	NOUN
admet-801	11	10	were	be	AUX
admet-801	11	11	observed	observe	VERB
admet-801	11	12	in	in	ADP
admet-801	11	13	almost	almost	ADV
admet-801	11	14	all	all	PRON
admet-801	11	15	parameters	parameter	NOUN
admet-801	11	16	at	at	ADP
admet-801	11	17	50	50	NUM
admet-801	11	18	and	and	CCONJ
admet-801	11	19	75	75	NUM
admet-801	11	20	rpm	rpm	NOUN
admet-801	11	21	(	(	PUNCT
admet-801	11	22	p	p	X
admet-801	11	23	<	<	X
admet-801	11	24	0.05	0.05	NUM
admet-801	11	25	)	)	PUNCT
admet-801	11	26	.	.	PUNCT
admet-801	12	1	a	a	DET
admet-801	12	2	similar	similar	ADJ
admet-801	12	3	dissolution	dissolution	NOUN
admet-801	12	4	profile	profile	NOUN
admet-801	12	5	(	(	PUNCT
admet-801	12	6	f2	f2	X
admet-801	12	7	>	>	X
admet-801	12	8	50	50	NUM
admet-801	12	9	)	)	PUNCT
admet-801	12	10	with	with	ADP
admet-801	12	11	a	a	DET
admet-801	12	12	pharmacopoeial	pharmacopoeial	ADJ
admet-801	12	13	dissolution	dissolution	NOUN
admet-801	12	14	method	method	NOUN
admet-801	12	15	(	(	PUNCT
admet-801	12	16	usp	usp	NOUN
admet-801	12	17	apparatus	apparatus	NOUN
admet-801	12	18	2	2	NUM
admet-801	12	19	at	at	ADP
admet-801	12	20	50	50	NUM
admet-801	12	21	rpm	rpm	NOUN
admet-801	12	22	and	and	CCONJ
admet-801	12	23	900	900	NUM
admet-801	12	24	ml	ml	NOUN
admet-801	12	25	of	of	ADP
admet-801	12	26	phosphate	phosphate	ADJ
admet-801	12	27	buffer	buffer	NOUN
admet-801	12	28	ph	ph	VERB
admet-801	12	29	5.8	5.8	NUM
admet-801	12	30	)	)	PUNCT
admet-801	12	31	and	and	CCONJ
admet-801	12	32	usp	usp	NOUN
admet-801	12	33	apparatus	apparatus	NOUN
admet-801	12	34	4	4	NUM
admet-801	12	35	(	(	PUNCT
admet-801	12	36	laminar	laminar	ADJ
admet-801	12	37	flow	flow	NOUN
admet-801	12	38	of	of	ADP
admet-801	12	39	16	16	NUM
admet-801	12	40	ml	ml	NOUN
admet-801	12	41	/	/	SYM
admet-801	12	42	min	min	NOUN
admet-801	12	43	,	,	PUNCT
admet-801	12	44	22.6	22.6	NUM
admet-801	12	45	mm	mm	NOUN
admet-801	12	46	cells	cell	NOUN
admet-801	12	47	,	,	PUNCT
admet-801	12	48	and	and	CCONJ
admet-801	12	49	ph	ph	X
admet-801	12	50	6.8	6.8	NUM
admet-801	12	51	)	)	PUNCT
admet-801	12	52	was	be	AUX
admet-801	12	53	observed	observe	VERB
admet-801	12	54	.	.	PUNCT
admet-801	13	1	the	the	DET
admet-801	13	2	weibull	weibull	PROPN
admet-801	13	3	function	function	NOUN
admet-801	13	4	was	be	AUX
admet-801	13	5	the	the	DET
admet-801	13	6	best	good	ADJ
admet-801	13	7	mathematical	mathematical	ADJ
admet-801	13	8	model	model	NOUN
admet-801	13	9	to	to	PART
admet-801	13	10	describe	describe	VERB
admet-801	13	11	the	the	DET
admet-801	13	12	in	in	ADV
admet-801	13	13	vitro	vitro	X
admet-801	13	14	release	release	NOUN
admet-801	13	15	performance	performance	NOUN
admet-801	13	16	of	of	ADP
admet-801	13	17	furosemide	furosemide	NOUN
admet-801	13	18	in	in	ADP
admet-801	13	19	the	the	DET
admet-801	13	20	three	three	NUM
admet-801	13	21	usp	usp	NOUN
admet-801	13	22	dissolution	dissolution	NOUN
admet-801	13	23	apparatuses	apparatus	NOUN
admet-801	13	24	.	.	PUNCT
admet-801	14	1	these	these	DET
admet-801	14	2	results	result	NOUN
admet-801	14	3	could	could	AUX
admet-801	14	4	be	be	AUX
admet-801	14	5	used	use	VERB
admet-801	14	6	to	to	PART
admet-801	14	7	manufacture	manufacture	VERB
admet-801	14	8	better	well	ADV
admet-801	14	9	furosemide	furosemide	ADJ
admet-801	14	10	dosage	dosage	NOUN
admet-801	14	11	forms	form	NOUN
admet-801	14	12	and	and	CCONJ
admet-801	14	13	decrease	decrease	VERB
admet-801	14	14	the	the	DET
admet-801	14	15	negative	negative	ADJ
admet-801	14	16	clinical	clinical	ADJ
admet-801	14	17	impact	impact	NOUN
admet-801	14	18	of	of	ADP
admet-801	14	19	current	current	ADJ
admet-801	14	20	furosemide	furosemide	ADJ
admet-801	14	21	formulations	formulation	NOUN
admet-801	14	22	.	.	PUNCT
admet-801	15	1	©	©	PROPN
admet-801	15	2	2020	2020	NUM
admet-801	15	3	by	by	ADP
admet-801	15	4	the	the	DET
admet-801	15	5	authors	author	NOUN
admet-801	15	6	.	.	PUNCT
admet-801	16	1	this	this	DET
admet-801	16	2	article	article	NOUN
admet-801	16	3	is	be	AUX
admet-801	16	4	an	an	DET
admet-801	16	5	open	open	ADJ
admet-801	16	6	-	-	PUNCT
admet-801	16	7	access	access	NOUN
admet-801	16	8	article	article	NOUN
admet-801	16	9	distributed	distribute	VERB
admet-801	16	10	under	under	ADP
admet-801	16	11	the	the	DET
admet-801	16	12	terms	term	NOUN
admet-801	16	13	and	and	CCONJ
admet-801	16	14	conditions	condition	NOUN
admet-801	16	15	of	of	ADP
admet-801	16	16	the	the	DET
admet-801	16	17	creative	creative	ADJ
admet-801	16	18	commons	common	NOUN
admet-801	16	19	attribution	attribution	NOUN
admet-801	16	20	license	license	NOUN
admet-801	16	21	(	(	PUNCT
admet-801	16	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-801	16	23	)	)	PUNCT
admet-801	16	24	.	.	PUNCT
admet-801	17	1	keywords	keyword	VERB
admet-801	17	2	flow	flow	NOUN
admet-801	17	3	-	-	PUNCT
admet-801	17	4	through	through	ADP
admet-801	17	5	cell	cell	NOUN
admet-801	17	6	method	method	NOUN
admet-801	17	7	;	;	PUNCT
admet-801	17	8	furosemide	furosemide	ADV
admet-801	17	9	;	;	PUNCT
admet-801	17	10	lasix	lasix	X
admet-801	17	11	®	®	NOUN
admet-801	17	12	drug	drug	NOUN
admet-801	17	13	product	product	NOUN
admet-801	17	14	;	;	PUNCT
admet-801	17	15	usp	usp	NOUN
admet-801	17	16	basket	basket	NOUN
admet-801	17	17	and	and	CCONJ
admet-801	17	18	paddle	paddle	NOUN
admet-801	17	19	apparatus	apparatus	NOUN
admet-801	17	20	introduction	introduction	NOUN
admet-801	17	21	furosemide	furosemide	NOUN
admet-801	17	22	is	be	AUX
admet-801	17	23	a	a	DET
admet-801	17	24	diuretic	diuretic	ADJ
admet-801	17	25	drug	drug	NOUN
admet-801	17	26	widely	widely	ADV
admet-801	17	27	used	use	VERB
admet-801	17	28	in	in	ADP
admet-801	17	29	the	the	DET
admet-801	17	30	treatment	treatment	NOUN
admet-801	17	31	of	of	ADP
admet-801	17	32	oedematous	oedematous	ADJ
admet-801	17	33	states	state	NOUN
admet-801	17	34	associated	associate	VERB
admet-801	17	35	with	with	ADP
admet-801	17	36	cardiac	cardiac	ADJ
admet-801	17	37	,	,	PUNCT
admet-801	17	38	chronic	chronic	ADJ
admet-801	17	39	renal	renal	ADJ
admet-801	17	40	failure	failure	NOUN
admet-801	17	41	,	,	PUNCT
admet-801	17	42	hypertension	hypertension	NOUN
admet-801	17	43	,	,	PUNCT
admet-801	17	44	congestive	congestive	ADJ
admet-801	17	45	heart	heart	NOUN
admet-801	17	46	failure	failure	NOUN
admet-801	17	47	,	,	PUNCT
admet-801	17	48	and	and	CCONJ
admet-801	17	49	cirrhosis	cirrhosis	NOUN
admet-801	17	50	[	[	X
admet-801	17	51	1	1	NUM
admet-801	17	52	]	]	PUNCT
admet-801	17	53	.	.	PUNCT
admet-801	18	1	furosemide	furosemide	PROPN
admet-801	18	2	is	be	AUX
admet-801	18	3	a	a	DET
admet-801	18	4	weak	weak	ADJ
admet-801	18	5	acid	acid	NOUN
admet-801	18	6	(	(	PUNCT
admet-801	18	7	pka	pka	NOUN
admet-801	18	8	=	=	NOUN
admet-801	18	9	3.8	3.8	NUM
admet-801	18	10	)	)	PUNCT
admet-801	18	11	with	with	ADP
admet-801	18	12	low	low	ADJ
admet-801	18	13	solubility	solubility	NOUN
admet-801	18	14	and	and	CCONJ
admet-801	18	15	permeability	permeability	NOUN
admet-801	18	16	[	[	X
admet-801	18	17	2	2	NUM
admet-801	18	18	]	]	PUNCT
admet-801	18	19	.	.	PUNCT
admet-801	19	1	according	accord	VERB
admet-801	19	2	to	to	ADP
admet-801	19	3	the	the	DET
admet-801	19	4	biopharmaceutical	biopharmaceutical	ADJ
admet-801	19	5	classification	classification	NOUN
admet-801	19	6	system	system	NOUN
admet-801	19	7	,	,	PUNCT
admet-801	19	8	drugs	drug	NOUN
admet-801	19	9	with	with	ADP
admet-801	19	10	these	these	DET
admet-801	19	11	characteristics	characteristic	NOUN
admet-801	19	12	belong	belong	VERB
admet-801	19	13	to	to	ADP
admet-801	19	14	class	class	NOUN
admet-801	19	15	iv	iv	NOUN
admet-801	19	16	[	[	X
admet-801	19	17	3	3	NUM
admet-801	19	18	]	]	PUNCT
admet-801	19	19	.	.	PUNCT
admet-801	20	1	the	the	DET
admet-801	20	2	chemical	chemical	ADJ
admet-801	20	3	structure	structure	NOUN
admet-801	20	4	of	of	ADP
admet-801	20	5	furosemide	furosemide	NOUN
admet-801	20	6	is	be	AUX
admet-801	20	7	shown	show	VERB
admet-801	20	8	in	in	ADP
admet-801	20	9	figure	figure	NOUN
admet-801	20	10	1	1	NUM
admet-801	20	11	.	.	PUNCT
admet-801	21	1	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	PROPN
admet-801	21	2	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	ADJ
admet-801	21	3	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-801	21	4	mailto:rmlopez@correo.xoc.uam.mx	mailto:rmlopez@correo.xoc.uam.mx	PROPN
admet-801	21	5	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-801	21	6	medina	medina	PROPN
admet-801	21	7	-	-	PUNCT
admet-801	21	8	lópez	lópez	PROPN
admet-801	21	9	et	et	PROPN
admet-801	21	10	al	al	PROPN
admet-801	21	11	.	.	PROPN
admet-801	21	12	admet	admet	PROPN
admet-801	21	13	&	&	CCONJ
admet-801	21	14	dmpk	dmpk	PROPN
admet-801	21	15	8(4	8(4	NOUN
admet-801	21	16	)	)	PUNCT
admet-801	21	17	(	(	PUNCT
admet-801	21	18	2020	2020	NUM
admet-801	21	19	)	)	PUNCT
admet-801	21	20	411	411	NUM
admet-801	21	21	-	-	SYM
admet-801	21	22	423	423	NUM
admet-801	21	23	412	412	NUM
admet-801	21	24	factors	factor	NOUN
admet-801	21	25	that	that	PRON
admet-801	21	26	affect	affect	VERB
admet-801	21	27	drug	drug	NOUN
admet-801	21	28	bioavailability	bioavailability	NOUN
admet-801	21	29	related	relate	VERB
admet-801	21	30	to	to	ADP
admet-801	21	31	the	the	DET
admet-801	21	32	pharmaceutical	pharmaceutical	ADJ
admet-801	21	33	dosage	dosage	NOUN
admet-801	21	34	form	form	NOUN
admet-801	21	35	and	and	CCONJ
admet-801	21	36	manufacturing	manufacturing	NOUN
admet-801	21	37	process	process	NOUN
admet-801	21	38	have	have	AUX
admet-801	21	39	been	be	AUX
admet-801	21	40	described	describe	VERB
admet-801	21	41	[	[	PUNCT
admet-801	21	42	4	4	NUM
admet-801	21	43	-	-	SYM
admet-801	21	44	5	5	NUM
admet-801	21	45	]	]	PUNCT
admet-801	21	46	.	.	PUNCT
admet-801	22	1	techniques	technique	NOUN
admet-801	22	2	and	and	CCONJ
admet-801	22	3	strategies	strategy	NOUN
admet-801	22	4	for	for	ADP
admet-801	22	5	the	the	DET
admet-801	22	6	development	development	NOUN
admet-801	22	7	of	of	ADP
admet-801	22	8	class	class	NOUN
admet-801	22	9	iv	iv	NUM
admet-801	22	10	drug	drug	NOUN
admet-801	22	11	formulations	formulation	NOUN
admet-801	22	12	have	have	AUX
admet-801	22	13	also	also	ADV
admet-801	22	14	been	be	AUX
admet-801	22	15	discussed	discuss	VERB
admet-801	22	16	[	[	X
admet-801	22	17	6	6	NUM
admet-801	22	18	]	]	PUNCT
admet-801	22	19	.	.	PUNCT
admet-801	23	1	this	this	DET
admet-801	23	2	information	information	NOUN
admet-801	23	3	can	can	AUX
admet-801	23	4	support	support	VERB
admet-801	23	5	the	the	DET
admet-801	23	6	design	design	NOUN
admet-801	23	7	of	of	ADP
admet-801	23	8	better	well	ADJ
admet-801	23	9	oral	oral	ADJ
admet-801	23	10	dosage	dosage	NOUN
admet-801	23	11	forms	form	NOUN
admet-801	23	12	of	of	ADP
admet-801	23	13	furosemide	furosemide	NOUN
admet-801	23	14	than	than	ADP
admet-801	23	15	those	those	PRON
admet-801	23	16	currently	currently	ADV
admet-801	23	17	available	available	ADJ
admet-801	23	18	.	.	PUNCT
admet-801	24	1	the	the	DET
admet-801	24	2	oral	oral	ADJ
admet-801	24	3	bioavailability	bioavailability	NOUN
admet-801	24	4	of	of	ADP
admet-801	24	5	furosemide	furosemide	NOUN
admet-801	24	6	has	have	AUX
admet-801	24	7	been	be	AUX
admet-801	24	8	reported	report	VERB
admet-801	24	9	to	to	PART
admet-801	24	10	be	be	AUX
admet-801	24	11	37–51	37–51	NUM
admet-801	24	12	%	%	NOUN
admet-801	25	1	[	[	X
admet-801	25	2	7	7	NUM
admet-801	25	3	]	]	PUNCT
admet-801	25	4	and	and	CCONJ
admet-801	25	5	60–70	60–70	NUM
admet-801	25	6	%	%	NOUN
admet-801	25	7	,	,	PUNCT
admet-801	25	8	with	with	ADP
admet-801	25	9	a	a	DET
admet-801	25	10	variable	variable	ADJ
admet-801	25	11	and	and	CCONJ
admet-801	25	12	erratic	erratic	ADJ
admet-801	25	13	absorption	absorption	NOUN
admet-801	25	14	[	[	X
admet-801	25	15	8	8	NUM
admet-801	25	16	]	]	PUNCT
admet-801	25	17	.	.	PUNCT
admet-801	26	1	for	for	ADP
admet-801	26	2	the	the	DET
admet-801	26	3	reference	reference	NOUN
admet-801	26	4	product	product	NOUN
admet-801	26	5	lasix	lasix	PROPN
admet-801	26	6	®	®	PROPN
admet-801	26	7	,	,	PUNCT
admet-801	26	8	an	an	DET
admet-801	26	9	absolute	absolute	ADJ
admet-801	26	10	bioavailability	bioavailability	NOUN
admet-801	26	11	of	of	ADP
admet-801	26	12	56	56	NUM
admet-801	26	13	%	%	NOUN
admet-801	26	14	has	have	AUX
admet-801	26	15	been	be	AUX
admet-801	26	16	observed	observe	VERB
admet-801	26	17	[	[	PUNCT
admet-801	26	18	9	9	NUM
admet-801	26	19	]	]	PUNCT
admet-801	26	20	.	.	PUNCT
admet-801	27	1	this	this	DET
admet-801	27	2	limited	limited	ADJ
admet-801	27	3	bioavailability	bioavailability	NOUN
admet-801	27	4	could	could	AUX
admet-801	27	5	be	be	AUX
admet-801	27	6	associated	associate	VERB
admet-801	27	7	with	with	ADP
admet-801	27	8	significant	significant	ADJ
admet-801	27	9	differences	difference	NOUN
admet-801	27	10	in	in	ADP
admet-801	27	11	the	the	DET
admet-801	27	12	dissolution	dissolution	ADJ
admet-801	27	13	behaviour	behaviour	NOUN
admet-801	27	14	of	of	ADP
admet-801	27	15	furosemide	furosemide	ADJ
admet-801	27	16	commercial	commercial	ADJ
admet-801	27	17	formulations	formulation	NOUN
admet-801	27	18	shown	show	VERB
admet-801	27	19	by	by	ADP
admet-801	27	20	several	several	ADJ
admet-801	27	21	authors	author	NOUN
admet-801	27	22	.	.	PUNCT
admet-801	28	1	kaojarern	kaojarern	PROPN
admet-801	28	2	et	et	PROPN
admet-801	28	3	al	al	PROPN
admet-801	28	4	.	.	PUNCT
admet-801	29	1	[	[	X
admet-801	29	2	10	10	NUM
admet-801	29	3	]	]	PUNCT
admet-801	29	4	reported	report	VERB
admet-801	29	5	an	an	DET
admet-801	29	6	in	in	ADP
admet-801	29	7	vitro	vitro	X
admet-801	29	8	dissolution	dissolution	NOUN
admet-801	29	9	study	study	NOUN
admet-801	29	10	of	of	ADP
admet-801	29	11	13	13	NUM
admet-801	29	12	brands	brand	NOUN
admet-801	29	13	of	of	ADP
admet-801	29	14	furosemide	furosemide	ADJ
admet-801	29	15	tablets	tablet	NOUN
admet-801	29	16	(	(	PUNCT
admet-801	29	17	40	40	NUM
admet-801	29	18	mg	mg	NOUN
admet-801	29	19	)	)	PUNCT
admet-801	29	20	,	,	PUNCT
admet-801	29	21	of	of	ADP
admet-801	29	22	which	which	PRON
admet-801	29	23	only	only	ADV
admet-801	29	24	four	four	NUM
admet-801	29	25	fulfil	fulfil	NOUN
admet-801	29	26	the	the	DET
admet-801	29	27	q	q	X
admet-801	29	28	pharmacopoeial	pharmacopoeial	ADJ
admet-801	29	29	specification	specification	NOUN
admet-801	29	30	.	.	PUNCT
admet-801	30	1	stüber	stüber	NOUN
admet-801	30	2	et	et	PROPN
admet-801	30	3	al	al	PROPN
admet-801	30	4	.	.	PUNCT
admet-801	31	1	[	[	X
admet-801	31	2	11	11	NUM
admet-801	31	3	]	]	PUNCT
admet-801	31	4	studied	study	VERB
admet-801	31	5	the	the	DET
admet-801	31	6	bioavailability	bioavailability	NOUN
admet-801	31	7	of	of	ADP
admet-801	31	8	four	four	NUM
admet-801	31	9	furosemide	furosemide	ADJ
admet-801	31	10	drug	drug	NOUN
admet-801	31	11	products	product	NOUN
admet-801	31	12	,	,	PUNCT
admet-801	31	13	of	of	ADP
admet-801	31	14	which	which	PRON
admet-801	31	15	three	three	NUM
admet-801	31	16	formulations	formulation	NOUN
admet-801	31	17	have	have	VERB
admet-801	31	18	bioavailabilities	bioavailabilitie	NOUN
admet-801	31	19	of	of	ADP
admet-801	31	20	81–83	81–83	NUM
admet-801	31	21	%	%	NOUN
admet-801	31	22	and	and	CCONJ
admet-801	31	23	lower	low	ADJ
admet-801	31	24	in	in	ADP
admet-801	31	25	vitro	vitro	X
admet-801	31	26	dissolution	dissolution	ADJ
admet-801	31	27	performance	performance	NOUN
admet-801	31	28	than	than	ADP
admet-801	31	29	the	the	DET
admet-801	31	30	reference	reference	NOUN
admet-801	31	31	in	in	ADP
admet-801	31	32	each	each	PRON
admet-801	31	33	of	of	ADP
admet-801	31	34	following	follow	VERB
admet-801	31	35	conditions	condition	NOUN
admet-801	31	36	:	:	PUNCT
admet-801	31	37	ph	ph	NOUN
admet-801	31	38	7.8	7.8	NUM
admet-801	31	39	/	/	SYM
admet-801	31	40	paddle	paddle	NOUN
admet-801	31	41	at	at	ADP
admet-801	31	42	25	25	NUM
admet-801	31	43	rpm	rpm	NOUN
admet-801	31	44	,	,	PUNCT
admet-801	31	45	ph	ph	VERB
admet-801	31	46	7.8	7.8	NUM
admet-801	31	47	/	/	SYM
admet-801	31	48	paddle	paddle	NOUN
admet-801	31	49	at	at	ADP
admet-801	31	50	50	50	NUM
admet-801	31	51	rpm	rpm	NOUN
admet-801	31	52	,	,	PUNCT
admet-801	31	53	ph	ph	VERB
admet-801	31	54	5.3	5.3	NUM
admet-801	31	55	/	/	SYM
admet-801	31	56	paddle	paddle	NOUN
admet-801	31	57	at	at	ADP
admet-801	31	58	50	50	NUM
admet-801	31	59	rpm	rpm	NOUN
admet-801	31	60	,	,	PUNCT
admet-801	31	61	and	and	CCONJ
admet-801	31	62	flow	flow	NOUN
admet-801	31	63	-	-	PUNCT
admet-801	31	64	through	through	ADP
admet-801	31	65	cell	cell	NOUN
admet-801	31	66	(	(	PUNCT
admet-801	31	67	100	100	NUM
admet-801	31	68	ml	ml	NOUN
admet-801	31	69	/	/	SYM
admet-801	31	70	h)/ph	h)/ph	NOUN
admet-801	31	71	7.8	7.8	NUM
admet-801	31	72	.	.	PUNCT
admet-801	32	1	the	the	DET
admet-801	32	2	difference	difference	NOUN
admet-801	32	3	in	in	ADP
admet-801	32	4	in	in	ADP
admet-801	32	5	vitro	vitro	X
admet-801	32	6	dissolution	dissolution	NOUN
admet-801	32	7	is	be	AUX
admet-801	32	8	more	more	ADV
admet-801	32	9	pronounced	pronounced	ADJ
admet-801	32	10	at	at	ADP
admet-801	32	11	ph	ph	PROPN
admet-801	32	12	5.3	5.3	NUM
admet-801	32	13	/	/	SYM
admet-801	32	14	paddle	paddle	NOUN
admet-801	32	15	at	at	ADP
admet-801	32	16	50	50	NUM
admet-801	32	17	rpm	rpm	NOUN
admet-801	32	18	.	.	PUNCT
admet-801	33	1	currently	currently	ADV
admet-801	33	2	,	,	PUNCT
admet-801	33	3	the	the	DET
admet-801	33	4	official	official	ADJ
admet-801	33	5	dissolution	dissolution	NOUN
admet-801	33	6	test	test	NOUN
admet-801	33	7	for	for	ADP
admet-801	33	8	furosemide	furosemide	ADJ
admet-801	33	9	tablets	tablet	NOUN
admet-801	33	10	is	be	AUX
admet-801	33	11	the	the	DET
admet-801	33	12	usp	usp	NOUN
admet-801	33	13	apparatus	apparatus	NOUN
admet-801	33	14	2	2	NUM
admet-801	33	15	at	at	ADP
admet-801	33	16	50	50	NUM
admet-801	33	17	rpm	rpm	NOUN
admet-801	33	18	with	with	ADP
admet-801	33	19	900	900	NUM
admet-801	33	20	ml	ml	NOUN
admet-801	33	21	of	of	ADP
admet-801	33	22	phosphate	phosphate	ADJ
admet-801	33	23	buffer	buffer	NOUN
admet-801	33	24	ph	ph	VERB
admet-801	33	25	5.8	5.8	NUM
admet-801	33	26	and	and	CCONJ
admet-801	33	27	no	no	DET
admet-801	33	28	less	less	ADJ
admet-801	33	29	than	than	ADP
admet-801	33	30	80	80	NUM
admet-801	33	31	%	%	NOUN
admet-801	33	32	should	should	AUX
admet-801	33	33	be	be	AUX
admet-801	33	34	dissolved	dissolve	VERB
admet-801	33	35	at	at	ADP
admet-801	33	36	60	60	NUM
admet-801	33	37	min	min	NOUN
admet-801	34	1	[	[	X
admet-801	34	2	12	12	NUM
admet-801	34	3	]	]	PUNCT
admet-801	34	4	.	.	PUNCT
admet-801	35	1	a	a	DET
admet-801	35	2	biowaiver	biowaiver	PROPN
admet-801	35	3	monograph	monograph	NOUN
admet-801	35	4	has	have	AUX
admet-801	35	5	been	be	AUX
admet-801	35	6	reported	report	VERB
admet-801	35	7	to	to	PART
admet-801	35	8	waiver	waiver	VERB
admet-801	35	9	the	the	DET
admet-801	35	10	in	in	ADP
admet-801	35	11	vivo	vivo	ADJ
admet-801	35	12	bioequivalence	bioequivalence	NOUN
admet-801	35	13	of	of	ADP
admet-801	35	14	furosemide	furosemide	ADJ
admet-801	35	15	solid	solid	ADJ
admet-801	35	16	oral	oral	ADJ
admet-801	35	17	dosage	dosage	NOUN
admet-801	35	18	forms	form	NOUN
admet-801	35	19	by	by	ADP
admet-801	35	20	in	in	ADP
admet-801	35	21	vitro	vitro	X
admet-801	35	22	dissolution	dissolution	NOUN
admet-801	35	23	studies	study	NOUN
admet-801	35	24	;	;	PUNCT
admet-801	35	25	however	however	ADV
admet-801	35	26	,	,	PUNCT
admet-801	35	27	given	give	VERB
admet-801	35	28	the	the	DET
admet-801	35	29	available	available	ADJ
admet-801	35	30	data	datum	NOUN
admet-801	35	31	,	,	PUNCT
admet-801	35	32	granero	granero	PROPN
admet-801	35	33	et	et	PROPN
admet-801	35	34	al	al	PROPN
admet-801	35	35	.	.	PUNCT
admet-801	36	1	[	[	X
admet-801	36	2	3	3	X
admet-801	36	3	]	]	PUNCT
admet-801	36	4	concluded	conclude	VERB
admet-801	36	5	that	that	SCONJ
admet-801	36	6	a	a	DET
admet-801	36	7	biowaiver	biowaiver	NOUN
admet-801	36	8	procedure	procedure	NOUN
admet-801	36	9	for	for	ADP
admet-801	36	10	this	this	DET
admet-801	36	11	drug	drug	NOUN
admet-801	36	12	can	can	AUX
admet-801	36	13	not	not	PART
admet-801	36	14	be	be	AUX
admet-801	36	15	justified	justify	VERB
admet-801	36	16	.	.	PUNCT
admet-801	37	1	low	low	ADJ
admet-801	37	2	solubility	solubility	NOUN
admet-801	37	3	and	and	CCONJ
admet-801	37	4	permeability	permeability	NOUN
admet-801	37	5	are	be	AUX
admet-801	37	6	problematic	problematic	ADJ
admet-801	37	7	characteristics	characteristic	NOUN
admet-801	37	8	of	of	ADP
admet-801	37	9	class	class	NOUN
admet-801	37	10	iv	iv	NUM
admet-801	37	11	drugs	drug	NOUN
admet-801	37	12	;	;	PUNCT
admet-801	37	13	thus	thus	ADV
admet-801	37	14	,	,	PUNCT
admet-801	37	15	the	the	DET
admet-801	37	16	determination	determination	NOUN
admet-801	37	17	of	of	ADP
admet-801	37	18	in	in	ADP
admet-801	37	19	vitro	vitro	X
admet-801	37	20	release	release	NOUN
admet-801	37	21	performance	performance	NOUN
admet-801	37	22	using	use	VERB
admet-801	37	23	different	different	ADJ
admet-801	37	24	agitation	agitation	NOUN
admet-801	37	25	rates	rate	NOUN
admet-801	37	26	,	,	PUNCT
admet-801	37	27	dissolution	dissolution	ADJ
admet-801	37	28	media	medium	NOUN
admet-801	37	29	,	,	PUNCT
admet-801	37	30	and	and	CCONJ
admet-801	37	31	dissolution	dissolution	NOUN
admet-801	37	32	apparatuses	apparatus	NOUN
admet-801	37	33	provides	provide	VERB
admet-801	37	34	important	important	ADJ
admet-801	37	35	information	information	NOUN
admet-801	37	36	for	for	ADP
admet-801	37	37	improving	improve	VERB
admet-801	37	38	the	the	DET
admet-801	37	39	manufacture	manufacture	NOUN
admet-801	37	40	and	and	CCONJ
admet-801	37	41	evaluation	evaluation	NOUN
admet-801	37	42	of	of	ADP
admet-801	37	43	generic	generic	ADJ
admet-801	37	44	formulations	formulation	NOUN
admet-801	37	45	.	.	PUNCT
admet-801	38	1	despite	despite	SCONJ
admet-801	38	2	the	the	DET
admet-801	38	3	wide	wide	ADJ
admet-801	38	4	use	use	NOUN
admet-801	38	5	of	of	ADP
admet-801	38	6	usp	usp	NOUN
admet-801	38	7	basket	basket	NOUN
admet-801	38	8	and	and	CCONJ
admet-801	38	9	paddle	paddle	NOUN
admet-801	38	10	apparatuses	apparatus	NOUN
admet-801	38	11	(	(	PUNCT
admet-801	38	12	usp	usp	NOUN
admet-801	38	13	apparatus	apparatus	NOUN
admet-801	38	14	1	1	NUM
admet-801	38	15	and	and	CCONJ
admet-801	38	16	2	2	NUM
admet-801	38	17	,	,	PUNCT
admet-801	38	18	respectively	respectively	ADV
admet-801	38	19	)	)	PUNCT
admet-801	38	20	to	to	PART
admet-801	38	21	monitor	monitor	VERB
admet-801	38	22	the	the	DET
admet-801	38	23	physical	physical	ADJ
admet-801	38	24	quality	quality	NOUN
admet-801	38	25	of	of	ADP
admet-801	38	26	tablets	tablet	NOUN
admet-801	38	27	and	and	CCONJ
admet-801	38	28	capsules	capsule	NOUN
admet-801	38	29	,	,	PUNCT
admet-801	38	30	several	several	ADJ
admet-801	38	31	investigations	investigation	NOUN
admet-801	38	32	about	about	ADP
admet-801	38	33	the	the	DET
admet-801	38	34	hydrodynamic	hydrodynamic	ADJ
admet-801	38	35	environment	environment	NOUN
admet-801	38	36	that	that	PRON
admet-801	38	37	surrounds	surround	VERB
admet-801	38	38	oral	oral	ADJ
admet-801	38	39	formulations	formulation	NOUN
admet-801	38	40	have	have	AUX
admet-801	38	41	reported	report	VERB
admet-801	38	42	that	that	SCONJ
admet-801	38	43	these	these	DET
admet-801	38	44	usp	usp	NOUN
admet-801	38	45	apparatuses	apparatus	NOUN
admet-801	38	46	do	do	AUX
admet-801	38	47	not	not	PART
admet-801	38	48	adequately	adequately	ADV
admet-801	38	49	reproduce	reproduce	VERB
admet-801	38	50	the	the	DET
admet-801	38	51	natural	natural	ADJ
admet-801	38	52	environment	environment	NOUN
admet-801	38	53	of	of	ADP
admet-801	38	54	the	the	DET
admet-801	38	55	gastrointestinal	gastrointestinal	ADJ
admet-801	38	56	tract	tract	NOUN
admet-801	39	1	[	[	X
admet-801	39	2	13	13	NUM
admet-801	39	3	-	-	SYM
admet-801	39	4	15	15	NUM
admet-801	39	5	]	]	PUNCT
admet-801	39	6	;	;	PUNCT
admet-801	39	7	thus	thus	ADV
admet-801	39	8	,	,	PUNCT
admet-801	39	9	it	it	PRON
admet-801	39	10	is	be	AUX
admet-801	39	11	necessary	necessary	ADJ
admet-801	39	12	to	to	PART
admet-801	39	13	document	document	VERB
admet-801	39	14	the	the	DET
admet-801	39	15	in	in	ADV
admet-801	39	16	vitro	vitro	X
admet-801	39	17	release	release	NOUN
admet-801	39	18	performance	performance	NOUN
admet-801	39	19	of	of	ADP
admet-801	39	20	poorly	poorly	ADV
admet-801	39	21	soluble	soluble	ADJ
admet-801	39	22	drugs	drug	NOUN
admet-801	39	23	under	under	ADP
admet-801	39	24	different	different	ADJ
admet-801	39	25	conditions	condition	NOUN
admet-801	39	26	to	to	PART
admet-801	39	27	establish	establish	VERB
admet-801	39	28	,	,	PUNCT
admet-801	39	29	in	in	ADP
admet-801	39	30	the	the	DET
admet-801	39	31	best	good	ADJ
admet-801	39	32	possible	possible	ADJ
admet-801	39	33	way	way	NOUN
admet-801	39	34	,	,	PUNCT
admet-801	39	35	the	the	DET
admet-801	39	36	environment	environment	NOUN
admet-801	39	37	in	in	ADP
admet-801	39	38	which	which	PRON
admet-801	39	39	the	the	DET
admet-801	39	40	solid	solid	ADJ
admet-801	39	41	dosage	dosage	NOUN
admet-801	39	42	forms	form	NOUN
admet-801	39	43	will	will	AUX
admet-801	39	44	be	be	AUX
admet-801	39	45	within	within	ADP
admet-801	39	46	the	the	DET
admet-801	39	47	gastrointestinal	gastrointestinal	ADJ
admet-801	39	48	tract	tract	NOUN
admet-801	39	49	.	.	PUNCT
admet-801	40	1	further	far	ADV
admet-801	40	2	,	,	PUNCT
admet-801	40	3	alternative	alternative	ADJ
admet-801	40	4	apparatuses	apparatus	NOUN
admet-801	40	5	must	must	AUX
admet-801	40	6	be	be	AUX
admet-801	40	7	developed	develop	VERB
admet-801	40	8	to	to	PART
admet-801	40	9	achieve	achieve	VERB
admet-801	40	10	this	this	DET
admet-801	40	11	goal	goal	NOUN
admet-801	40	12	.	.	PUNCT
admet-801	41	1	the	the	DET
admet-801	41	2	flowthrough	flowthrough	ADJ
admet-801	41	3	cell	cell	NOUN
admet-801	41	4	method	method	NOUN
admet-801	41	5	(	(	PUNCT
admet-801	41	6	usp	usp	NOUN
admet-801	41	7	apparatus	apparatus	NOUN
admet-801	41	8	4	4	NUM
admet-801	41	9	)	)	PUNCT
admet-801	41	10	has	have	AUX
admet-801	41	11	been	be	AUX
admet-801	41	12	introduced	introduce	VERB
admet-801	41	13	as	as	ADP
admet-801	41	14	a	a	DET
admet-801	41	15	dissolution	dissolution	NOUN
admet-801	41	16	apparatus	apparatus	NOUN
admet-801	41	17	to	to	PART
admet-801	41	18	elucidate	elucidate	VERB
admet-801	41	19	the	the	DET
admet-801	41	20	rate	rate	NOUN
admet-801	41	21	and	and	CCONJ
admet-801	41	22	extent	extent	NOUN
admet-801	41	23	of	of	ADP
admet-801	41	24	the	the	DET
admet-801	41	25	dissolution	dissolution	NOUN
admet-801	41	26	of	of	ADP
admet-801	41	27	drugs	drug	NOUN
admet-801	41	28	with	with	ADP
admet-801	41	29	low	low	ADJ
admet-801	41	30	solubility	solubility	NOUN
admet-801	41	31	under	under	ADP
admet-801	41	32	sink	sink	NOUN
admet-801	41	33	conditions	condition	NOUN
admet-801	41	34	[	[	X
admet-801	41	35	16	16	NUM
admet-801	41	36	]	]	PUNCT
admet-801	41	37	.	.	PUNCT
admet-801	42	1	usp	usp	PROPN
admet-801	42	2	apparatus	apparatus	PROPN
admet-801	42	3	4	4	NUM
admet-801	42	4	is	be	AUX
admet-801	42	5	more	more	ADV
admet-801	42	6	reliable	reliable	ADJ
admet-801	42	7	,	,	PUNCT
admet-801	42	8	reproducible	reproducible	ADJ
admet-801	42	9	,	,	PUNCT
admet-801	42	10	and	and	CCONJ
admet-801	42	11	discriminative	discriminative	NOUN
admet-801	42	12	than	than	ADP
admet-801	42	13	the	the	DET
admet-801	42	14	other	other	ADJ
admet-801	42	15	methods	method	NOUN
admet-801	42	16	[	[	X
admet-801	42	17	17	17	NUM
admet-801	42	18	]	]	PUNCT
admet-801	42	19	,	,	PUNCT
admet-801	42	20	and	and	CCONJ
admet-801	42	21	it	it	PRON
admet-801	42	22	generates	generate	VERB
admet-801	42	23	a	a	DET
admet-801	42	24	hydrodynamic	hydrodynamic	ADJ
admet-801	42	25	environment	environment	NOUN
admet-801	42	26	similar	similar	ADJ
admet-801	42	27	to	to	ADP
admet-801	42	28	that	that	PRON
admet-801	42	29	inside	inside	ADP
admet-801	42	30	the	the	DET
admet-801	42	31	gastrointestinal	gastrointestinal	ADJ
admet-801	42	32	tract	tract	NOUN
admet-801	42	33	[	[	X
admet-801	42	34	18	18	NUM
admet-801	42	35	]	]	PUNCT
admet-801	42	36	.	.	PUNCT
admet-801	43	1	furthermore	furthermore	ADV
admet-801	43	2	,	,	PUNCT
admet-801	43	3	an	an	PRON
admet-801	43	4	in	in	ADP
admet-801	43	5	vitro	vitro	NOUN
admet-801	43	6	/	/	SYM
admet-801	43	7	in	in	ADP
admet-801	43	8	vivo	vivo	ADJ
admet-801	43	9	correlation	correlation	NOUN
admet-801	43	10	(	(	PUNCT
admet-801	43	11	ivivc	ivivc	PROPN
admet-801	43	12	)	)	PUNCT
admet-801	43	13	has	have	AUX
admet-801	43	14	been	be	AUX
admet-801	43	15	established	establish	VERB
admet-801	43	16	between	between	ADP
admet-801	43	17	the	the	DET
admet-801	43	18	in	in	X
admet-801	43	19	vitro	vitro	X
admet-801	43	20	data	datum	NOUN
admet-801	43	21	generated	generate	VERB
admet-801	43	22	with	with	ADP
admet-801	43	23	this	this	DET
admet-801	43	24	apparatus	apparatus	NOUN
admet-801	43	25	and	and	CCONJ
admet-801	43	26	in	in	ADP
admet-801	43	27	vivo	vivo	ADJ
admet-801	43	28	parameters	parameter	NOUN
admet-801	43	29	[	[	X
admet-801	43	30	19,20	19,20	X
admet-801	43	31	]	]	PUNCT
admet-801	43	32	.	.	PUNCT
admet-801	44	1	the	the	DET
admet-801	44	2	aim	aim	NOUN
admet-801	44	3	of	of	ADP
admet-801	44	4	this	this	DET
admet-801	44	5	study	study	NOUN
admet-801	44	6	was	be	AUX
admet-801	44	7	to	to	PART
admet-801	44	8	evaluate	evaluate	VERB
admet-801	44	9	the	the	DET
admet-801	44	10	in	in	ADV
admet-801	44	11	vitro	vitro	X
admet-801	44	12	release	release	NOUN
admet-801	44	13	performance	performance	NOUN
admet-801	44	14	of	of	ADP
admet-801	44	15	furosemide	furosemide	ADJ
admet-801	44	16	reference	reference	NOUN
admet-801	44	17	tablets	tablet	NOUN
admet-801	44	18	in	in	ADP
admet-801	44	19	the	the	DET
admet-801	44	20	hydrodynamic	hydrodynamic	ADJ
admet-801	44	21	environments	environment	NOUN
admet-801	44	22	generated	generate	VERB
admet-801	44	23	by	by	ADP
admet-801	44	24	different	different	ADJ
admet-801	44	25	usp	usp	NOUN
admet-801	44	26	apparatuses	apparatus	NOUN
admet-801	44	27	and	and	CCONJ
admet-801	44	28	dissolution	dissolution	ADJ
admet-801	44	29	media	medium	NOUN
admet-801	44	30	of	of	ADP
admet-801	44	31	physiological	physiological	ADJ
admet-801	44	32	relevance	relevance	NOUN
admet-801	44	33	to	to	PART
admet-801	44	34	identify	identify	VERB
admet-801	44	35	the	the	DET
admet-801	44	36	rate	rate	NOUN
admet-801	44	37	and	and	CCONJ
admet-801	44	38	extent	extent	NOUN
admet-801	44	39	of	of	ADP
admet-801	44	40	furosemide	furosemide	ADJ
admet-801	44	41	dissolution	dissolution	NOUN
admet-801	44	42	under	under	ADP
admet-801	44	43	these	these	DET
admet-801	44	44	conditions	condition	NOUN
admet-801	44	45	.	.	PUNCT
admet-801	45	1	this	this	DET
admet-801	45	2	information	information	NOUN
admet-801	45	3	will	will	AUX
admet-801	45	4	reflect	reflect	VERB
admet-801	45	5	the	the	DET
admet-801	45	6	characteristics	characteristic	NOUN
admet-801	45	7	of	of	ADP
admet-801	45	8	the	the	DET
admet-801	45	9	reference	reference	NOUN
admet-801	45	10	drug	drug	NOUN
admet-801	45	11	product	product	NOUN
admet-801	45	12	that	that	PRON
admet-801	45	13	can	can	AUX
admet-801	45	14	be	be	AUX
admet-801	45	15	considered	consider	VERB
admet-801	45	16	in	in	ADP
admet-801	45	17	the	the	DET
admet-801	45	18	preparation	preparation	NOUN
admet-801	45	19	of	of	ADP
admet-801	45	20	a	a	DET
admet-801	45	21	generic	generic	ADJ
admet-801	45	22	formulation	formulation	NOUN
admet-801	45	23	.	.	PUNCT
admet-801	46	1	lasix	lasix	ADJ
admet-801	46	2	®	®	NOUN
admet-801	46	3	tablets	tablet	NOUN
admet-801	46	4	were	be	AUX
admet-801	46	5	tested	test	VERB
admet-801	46	6	with	with	ADP
admet-801	46	7	0.1	0.1	NUM
admet-801	46	8	m	m	PROPN
admet-801	46	9	hydrochloric	hydrochloric	ADJ
admet-801	46	10	acid	acid	NOUN
admet-801	46	11	,	,	PUNCT
admet-801	46	12	acetate	acetate	NOUN
admet-801	46	13	buffer	buffer	NOUN
admet-801	46	14	(	(	PUNCT
admet-801	46	15	ph	ph	NOUN
admet-801	46	16	4.5	4.5	NUM
admet-801	46	17	)	)	PUNCT
admet-801	46	18	,	,	PUNCT
admet-801	46	19	and	and	CCONJ
admet-801	46	20	phosphate	phosphate	ADJ
admet-801	46	21	buffer	buffer	NOUN
admet-801	46	22	(	(	PUNCT
admet-801	46	23	ph	ph	NOUN
admet-801	46	24	6.8	6.8	NUM
admet-801	46	25	)	)	PUNCT
admet-801	46	26	using	use	VERB
admet-801	46	27	usp	usp	NOUN
admet-801	46	28	apparatuses	apparatus	NOUN
admet-801	46	29	1	1	NUM
admet-801	46	30	and	and	CCONJ
admet-801	46	31	2	2	NUM
admet-801	46	32	(	(	PUNCT
admet-801	46	33	at	at	ADP
admet-801	46	34	different	different	ADJ
admet-801	46	35	agitation	agitation	NOUN
admet-801	46	36	rates	rate	NOUN
admet-801	46	37	)	)	PUNCT
admet-801	46	38	and	and	CCONJ
admet-801	46	39	usp	usp	NOUN
admet-801	46	40	apparatus	apparatus	NOUN
admet-801	46	41	4	4	NUM
admet-801	46	42	.	.	PUNCT
admet-801	46	43	figure	figure	NOUN
admet-801	46	44	1	1	NUM
admet-801	46	45	.	.	PUNCT
admet-801	46	46	chemical	chemical	ADJ
admet-801	46	47	structure	structure	NOUN
admet-801	46	48	of	of	ADP
admet-801	46	49	furosemide	furosemide	NOUN
admet-801	46	50	.	.	PUNCT
admet-801	47	1	admet	admet	PROPN
admet-801	47	2	&	&	CCONJ
admet-801	47	3	dmpk	dmpk	PROPN
admet-801	47	4	8(4	8(4	NOUN
admet-801	47	5	)	)	PUNCT
admet-801	47	6	(	(	PUNCT
admet-801	47	7	2020	2020	NUM
admet-801	47	8	)	)	PUNCT
admet-801	47	9	411	411	NUM
admet-801	47	10	-	-	SYM
admet-801	47	11	423	423	NUM
admet-801	47	12	in	in	ADP
admet-801	47	13	vitro	vitro	X
admet-801	47	14	release	release	NOUN
admet-801	47	15	studies	study	NOUN
admet-801	47	16	of	of	ADP
admet-801	47	17	furosemide	furosemide	ADJ
admet-801	47	18	doi	doi	NOUN
admet-801	47	19	:	:	PUNCT
admet-801	47	20	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	VERB
admet-801	47	21	413	413	NUM
admet-801	47	22	experimental	experimental	ADJ
admet-801	47	23	materials	material	NOUN
admet-801	47	24	lasix	lasix	X
admet-801	47	25	®	®	NOUN
admet-801	47	26	furosemide	furosemide	NOUN
admet-801	47	27	tablets	tablet	NOUN
admet-801	47	28	(	(	PUNCT
admet-801	47	29	sanofi	sanofi	NOUN
admet-801	47	30	-	-	PUNCT
admet-801	47	31	aventis	aventis	PROPN
admet-801	47	32	de	de	PROPN
admet-801	47	33	mexico	mexico	PROPN
admet-801	47	34	,	,	PUNCT
admet-801	47	35	s.a	s.a	PROPN
admet-801	47	36	.	.	PROPN
admet-801	47	37	de	de	PROPN
admet-801	47	38	c.v	c.v	PROPN
admet-801	47	39	.	.	PROPN
admet-801	47	40	,	,	PUNCT
admet-801	47	41	mexico	mexico	PROPN
admet-801	47	42	city	city	PROPN
admet-801	47	43	,	,	PUNCT
admet-801	47	44	mexico	mexico	PROPN
admet-801	47	45	)	)	PUNCT
admet-801	47	46	were	be	AUX
admet-801	47	47	used	use	VERB
admet-801	47	48	.	.	PUNCT
admet-801	48	1	mexican	mexican	ADJ
admet-801	48	2	health	health	NOUN
admet-801	48	3	authorities	authority	NOUN
admet-801	48	4	have	have	AUX
admet-801	48	5	designated	designate	VERB
admet-801	48	6	this	this	DET
admet-801	48	7	formulation	formulation	NOUN
admet-801	48	8	as	as	ADP
admet-801	48	9	a	a	DET
admet-801	48	10	reference	reference	NOUN
admet-801	48	11	product	product	NOUN
admet-801	48	12	to	to	PART
admet-801	48	13	be	be	AUX
admet-801	48	14	used	use	VERB
admet-801	48	15	in	in	ADP
admet-801	48	16	dissolution	dissolution	NOUN
admet-801	48	17	and	and	CCONJ
admet-801	48	18	bioequivalence	bioequivalence	NOUN
admet-801	48	19	studies	study	NOUN
admet-801	48	20	[	[	X
admet-801	48	21	21	21	NUM
admet-801	48	22	]	]	PUNCT
admet-801	48	23	.	.	PUNCT
admet-801	49	1	reagents	reagent	NOUN
admet-801	49	2	hydrochloric	hydrochloric	ADJ
admet-801	49	3	acid	acid	NOUN
admet-801	49	4	,	,	PUNCT
admet-801	49	5	sodium	sodium	NOUN
admet-801	49	6	acetate	acetate	NOUN
admet-801	49	7	,	,	PUNCT
admet-801	49	8	acetic	acetic	ADJ
admet-801	49	9	acid	acid	NOUN
admet-801	49	10	,	,	PUNCT
admet-801	49	11	and	and	CCONJ
admet-801	49	12	phosphate	phosphate	ADJ
admet-801	49	13	salts	salt	NOUN
admet-801	49	14	were	be	AUX
admet-801	49	15	purchased	purchase	VERB
admet-801	49	16	from	from	ADP
admet-801	49	17	j.t	j.t	PROPN
admet-801	49	18	.	.	PROPN
admet-801	49	19	bakermexico	bakermexico	NOUN
admet-801	49	20	(	(	PUNCT
admet-801	49	21	xalostoc	xalostoc	PROPN
admet-801	49	22	,	,	PUNCT
admet-801	49	23	mexico	mexico	PROPN
admet-801	49	24	)	)	PUNCT
admet-801	49	25	.	.	PUNCT
admet-801	50	1	furosemide	furosemide	ADJ
admet-801	50	2	reference	reference	PROPN
admet-801	50	3	standard	standard	NOUN
admet-801	50	4	was	be	AUX
admet-801	50	5	purchased	purchase	VERB
admet-801	50	6	from	from	ADP
admet-801	50	7	sigma	sigma	PROPN
admet-801	50	8	-	-	PUNCT
admet-801	50	9	aldrich	aldrich	PROPN
admet-801	50	10	co.	co.	PROPN
admet-801	50	11	(	(	PUNCT
admet-801	50	12	st	st	PROPN
admet-801	50	13	.	.	PROPN
admet-801	50	14	louis	louis	PROPN
admet-801	50	15	,	,	PUNCT
admet-801	50	16	mo	mo	PROPN
admet-801	50	17	,	,	PUNCT
admet-801	50	18	usa	usa	PROPN
admet-801	50	19	)	)	PUNCT
admet-801	50	20	.	.	PUNCT
admet-801	51	1	all	all	DET
admet-801	51	2	samples	sample	NOUN
admet-801	51	3	were	be	AUX
admet-801	51	4	filtered	filter	VERB
admet-801	51	5	through	through	ADP
admet-801	51	6	0.45	0.45	NUM
admet-801	51	7	µm	µm	ADP
admet-801	51	8	nitrocellulose	nitrocellulose	NOUN
admet-801	51	9	filters	filter	NOUN
admet-801	51	10	(	(	PUNCT
admet-801	51	11	millipore	millipore	PROPN
admet-801	51	12	,	,	PUNCT
admet-801	51	13	ireland	ireland	PROPN
admet-801	51	14	)	)	PUNCT
admet-801	51	15	.	.	PUNCT
admet-801	52	1	standard	standard	ADJ
admet-801	52	2	solutions	solution	NOUN
admet-801	52	3	were	be	AUX
admet-801	52	4	prepared	prepare	VERB
admet-801	52	5	by	by	ADP
admet-801	52	6	serial	serial	ADJ
admet-801	52	7	dilutions	dilution	NOUN
admet-801	52	8	of	of	ADP
admet-801	52	9	the	the	DET
admet-801	52	10	stock	stock	NOUN
admet-801	52	11	solutions	solution	NOUN
admet-801	52	12	of	of	ADP
admet-801	52	13	furosemide	furosemide	NOUN
admet-801	52	14	(	(	PUNCT
admet-801	52	15	1	1	NUM
admet-801	52	16	mg	mg	NUM
admet-801	52	17	/	/	SYM
admet-801	52	18	ml	ml	NOUN
admet-801	52	19	)	)	PUNCT
admet-801	52	20	to	to	PART
admet-801	52	21	achieve	achieve	VERB
admet-801	52	22	concentrations	concentration	NOUN
admet-801	52	23	of	of	ADP
admet-801	52	24	1.25–20	1.25–20	NUM
admet-801	52	25	µg	µg	ADJ
admet-801	52	26	/	/	SYM
admet-801	52	27	ml	ml	NOUN
admet-801	52	28	.	.	PUNCT
admet-801	53	1	the	the	DET
admet-801	53	2	dissolution	dissolution	NOUN
admet-801	53	3	media	medium	NOUN
admet-801	53	4	comprised	comprise	VERB
admet-801	53	5	0.1	0.1	NUM
admet-801	53	6	n	n	CCONJ
admet-801	53	7	hydrochloric	hydrochloric	ADJ
admet-801	53	8	acid	acid	NOUN
admet-801	53	9	,	,	PUNCT
admet-801	53	10	acetate	acetate	NOUN
admet-801	53	11	buffer	buffer	NOUN
admet-801	53	12	(	(	PUNCT
admet-801	53	13	ph	ph	NOUN
admet-801	53	14	4.5	4.5	NUM
admet-801	53	15	)	)	PUNCT
admet-801	53	16	,	,	PUNCT
admet-801	53	17	and	and	CCONJ
admet-801	53	18	phosphate	phosphate	ADJ
admet-801	53	19	buffer	buffer	NOUN
admet-801	53	20	(	(	PUNCT
admet-801	53	21	ph	ph	NOUN
admet-801	53	22	6.8	6.8	NUM
admet-801	53	23	)	)	PUNCT
admet-801	53	24	.	.	PUNCT
admet-801	54	1	content	content	NOUN
admet-801	54	2	uniformity	uniformity	NOUN
admet-801	54	3	and	and	CCONJ
admet-801	54	4	assay	assay	NOUN
admet-801	54	5	content	content	NOUN
admet-801	54	6	uniformity	uniformity	NOUN
admet-801	54	7	and	and	CCONJ
admet-801	54	8	assay	assay	NOUN
admet-801	54	9	tests	test	NOUN
admet-801	54	10	were	be	AUX
admet-801	54	11	performed	perform	VERB
admet-801	54	12	with	with	ADP
admet-801	54	13	the	the	DET
admet-801	54	14	drug	drug	NOUN
admet-801	54	15	product	product	NOUN
admet-801	54	16	according	accord	VERB
admet-801	54	17	to	to	ADP
admet-801	54	18	the	the	DET
admet-801	54	19	procedures	procedure	NOUN
admet-801	54	20	described	describe	VERB
admet-801	54	21	in	in	ADP
admet-801	54	22	the	the	DET
admet-801	54	23	usp	usp	NOUN
admet-801	54	24	[	[	X
admet-801	54	25	12	12	NUM
admet-801	54	26	]	]	PUNCT
admet-801	54	27	.	.	PUNCT
admet-801	55	1	usp	usp	PROPN
admet-801	55	2	basket	basket	NOUN
admet-801	55	3	and	and	CCONJ
admet-801	55	4	paddle	paddle	NOUN
admet-801	55	5	apparatus	apparatus	NOUN
admet-801	55	6	dissolution	dissolution	NOUN
admet-801	55	7	profiles	profile	NOUN
admet-801	55	8	of	of	ADP
admet-801	55	9	furosemide	furosemide	NOUN
admet-801	55	10	were	be	AUX
admet-801	55	11	obtained	obtain	VERB
admet-801	55	12	using	use	VERB
admet-801	55	13	usp	usp	NOUN
admet-801	55	14	apparatuses	apparatus	NOUN
admet-801	55	15	1	1	NUM
admet-801	55	16	and	and	CCONJ
admet-801	55	17	2	2	NUM
admet-801	55	18	(	(	PUNCT
admet-801	55	19	model	model	NOUN
admet-801	55	20	at-7	at-7	ADJ
admet-801	55	21	smart	smart	PROPN
admet-801	55	22	,	,	PUNCT
admet-801	55	23	sotax	sotax	NOUN
admet-801	55	24	,	,	PUNCT
admet-801	55	25	basel	basel	PROPN
admet-801	55	26	,	,	PUNCT
admet-801	55	27	switzerland	switzerland	PROPN
admet-801	55	28	)	)	PUNCT
admet-801	55	29	with	with	ADP
admet-801	55	30	25	25	NUM
admet-801	55	31	,	,	PUNCT
admet-801	55	32	50	50	NUM
admet-801	55	33	,	,	PUNCT
admet-801	55	34	and	and	CCONJ
admet-801	55	35	75	75	NUM
admet-801	55	36	rpm	rpm	NOUN
admet-801	55	37	agitation	agitation	NOUN
admet-801	55	38	rates	rate	NOUN
admet-801	55	39	.	.	PUNCT
admet-801	56	1	additionally	additionally	ADV
admet-801	56	2	,	,	PUNCT
admet-801	56	3	pharmacopoeial	pharmacopoeial	ADJ
admet-801	56	4	dissolution	dissolution	NOUN
admet-801	56	5	conditions	condition	NOUN
admet-801	56	6	(	(	PUNCT
admet-801	56	7	usp	usp	NOUN
admet-801	56	8	apparatus	apparatus	NOUN
admet-801	56	9	2	2	NUM
admet-801	56	10	at	at	ADP
admet-801	56	11	50	50	NUM
admet-801	56	12	rpm	rpm	NOUN
admet-801	56	13	with	with	ADP
admet-801	56	14	phosphate	phosphate	ADJ
admet-801	56	15	buffer	buffer	NOUN
admet-801	56	16	(	(	PUNCT
admet-801	56	17	ph	ph	NOUN
admet-801	56	18	5.8	5.8	NUM
admet-801	56	19	)	)	PUNCT
admet-801	56	20	)	)	PUNCT
admet-801	56	21	were	be	AUX
admet-801	56	22	tested	test	VERB
admet-801	56	23	[	[	X
admet-801	56	24	12	12	NUM
admet-801	56	25	]	]	PUNCT
admet-801	56	26	.	.	PUNCT
admet-801	57	1	an	an	DET
admet-801	57	2	ultravioletvisible	ultravioletvisible	ADJ
admet-801	57	3	(	(	PUNCT
admet-801	57	4	uv	uv	NOUN
admet-801	57	5	/	/	SYM
admet-801	57	6	vis	vis	X
admet-801	57	7	)	)	PUNCT
admet-801	57	8	spectrophotometer	spectrophotometer	NOUN
admet-801	57	9	(	(	PUNCT
admet-801	57	10	model	model	NOUN
admet-801	57	11	lambda	lambda	NOUN
admet-801	57	12	35	35	NUM
admet-801	57	13	,	,	PUNCT
admet-801	57	14	perkin	perkin	PROPN
admet-801	57	15	elmer	elmer	PROPN
admet-801	57	16	,	,	PUNCT
admet-801	57	17	usa	usa	PROPN
admet-801	57	18	)	)	PUNCT
admet-801	57	19	with	with	ADP
admet-801	57	20	1	1	NUM
admet-801	57	21	mm	mm	NOUN
admet-801	57	22	flow	flow	NOUN
admet-801	57	23	cells	cell	NOUN
admet-801	57	24	was	be	AUX
admet-801	57	25	used	use	VERB
admet-801	57	26	.	.	PUNCT
admet-801	58	1	the	the	DET
admet-801	58	2	equipment	equipment	NOUN
admet-801	58	3	was	be	AUX
admet-801	58	4	controlled	control	VERB
admet-801	58	5	by	by	ADP
admet-801	58	6	specific	specific	ADJ
admet-801	58	7	software	software	NOUN
admet-801	58	8	designed	design	VERB
admet-801	58	9	by	by	ADP
admet-801	58	10	sotax	sotax	PROPN
admet-801	58	11	.	.	PUNCT
admet-801	59	1	furosemide	furosemide	ADJ
admet-801	59	2	tablets	tablet	NOUN
admet-801	59	3	were	be	AUX
admet-801	59	4	sprinkled	sprinkle	VERB
admet-801	59	5	on	on	ADP
admet-801	59	6	900	900	NUM
admet-801	59	7	ml	ml	NOUN
admet-801	59	8	of	of	ADP
admet-801	59	9	0.1	0.1	NUM
admet-801	59	10	n	n	PRON
admet-801	59	11	hydrochloric	hydrochloric	ADJ
admet-801	59	12	acid	acid	NOUN
admet-801	59	13	,	,	PUNCT
admet-801	59	14	acetate	acetate	NOUN
admet-801	59	15	buffer	buffer	NOUN
admet-801	59	16	(	(	PUNCT
admet-801	59	17	ph	ph	NOUN
admet-801	59	18	4.5	4.5	NUM
admet-801	59	19	)	)	PUNCT
admet-801	59	20	,	,	PUNCT
admet-801	59	21	and	and	CCONJ
admet-801	59	22	phosphate	phosphate	ADJ
admet-801	59	23	buffer	buffer	NOUN
admet-801	59	24	(	(	PUNCT
admet-801	59	25	ph	ph	NOUN
admet-801	59	26	6.8	6.8	NUM
admet-801	59	27	)	)	PUNCT
admet-801	59	28	at	at	ADP
admet-801	59	29	37.0	37.0	NUM
admet-801	59	30	±	±	NUM
admet-801	59	31	0.5	0.5	NUM
admet-801	59	32	°	°	ADP
admet-801	59	33	c	c	NOUN
admet-801	59	34	.	.	PUNCT
admet-801	60	1	samples	sample	NOUN
admet-801	60	2	were	be	AUX
admet-801	60	3	taken	take	VERB
admet-801	60	4	automatically	automatically	ADV
admet-801	60	5	every	every	DET
admet-801	60	6	5	5	NUM
admet-801	60	7	min	min	NOUN
admet-801	60	8	for	for	ADP
admet-801	60	9	60	60	NUM
admet-801	60	10	min	min	NOUN
admet-801	60	11	.	.	PROPN
admet-801	60	12	dissolved	dissolve	VERB
admet-801	60	13	furosemide	furosemide	NOUN
admet-801	60	14	was	be	AUX
admet-801	60	15	quantified	quantify	VERB
admet-801	60	16	with	with	ADP
admet-801	60	17	standard	standard	ADJ
admet-801	60	18	calibration	calibration	NOUN
admet-801	60	19	curves	curve	NOUN
admet-801	60	20	,	,	PUNCT
admet-801	60	21	in	in	ADP
admet-801	60	22	each	each	DET
admet-801	60	23	dissolution	dissolution	NOUN
admet-801	60	24	medium	medium	NOUN
admet-801	60	25	,	,	PUNCT
admet-801	60	26	at	at	ADP
admet-801	60	27	274	274	NUM
admet-801	60	28	nm	nm	NOUN
admet-801	60	29	.	.	PUNCT
admet-801	61	1	flow	flow	NOUN
admet-801	61	2	-	-	PUNCT
admet-801	61	3	through	through	ADP
admet-801	61	4	cell	cell	NOUN
admet-801	61	5	method	method	NOUN
admet-801	61	6	dissolution	dissolution	NOUN
admet-801	61	7	profiles	profile	NOUN
admet-801	61	8	of	of	ADP
admet-801	61	9	furosemide	furosemide	NOUN
admet-801	61	10	were	be	AUX
admet-801	61	11	obtained	obtain	VERB
admet-801	61	12	with	with	ADP
admet-801	61	13	usp	usp	NOUN
admet-801	61	14	apparatus	apparatus	NOUN
admet-801	61	15	4	4	NUM
admet-801	61	16	(	(	PUNCT
admet-801	61	17	model	model	NOUN
admet-801	61	18	ce6	ce6	PROPN
admet-801	61	19	,	,	PUNCT
admet-801	61	20	sotax	sotax	PROPN
admet-801	61	21	ag	ag	PROPN
admet-801	61	22	,	,	PUNCT
admet-801	61	23	basel	basel	PROPN
admet-801	61	24	,	,	PUNCT
admet-801	61	25	switzerland	switzerland	PROPN
admet-801	61	26	)	)	PUNCT
admet-801	61	27	with	with	ADP
admet-801	61	28	22.6	22.6	NUM
admet-801	61	29	mm	mm	NOUN
admet-801	61	30	cells	cell	NOUN
admet-801	61	31	(	(	PUNCT
admet-801	61	32	i.d	i.d	PROPN
admet-801	61	33	.	.	PROPN
admet-801	61	34	)	)	PUNCT
admet-801	61	35	.	.	PUNCT
admet-801	62	1	the	the	DET
admet-801	62	2	laminar	laminar	ADJ
admet-801	62	3	flow	flow	NOUN
admet-801	62	4	(	(	PUNCT
admet-801	62	5	originated	originate	VERB
admet-801	62	6	with	with	ADP
admet-801	62	7	6	6	NUM
admet-801	62	8	g	g	NOUN
admet-801	62	9	of	of	ADP
admet-801	62	10	glass	glass	NOUN
admet-801	62	11	beads	bead	NOUN
admet-801	62	12	)	)	PUNCT
admet-801	62	13	of	of	ADP
admet-801	62	14	16	16	NUM
admet-801	62	15	ml	ml	NOUN
admet-801	62	16	/	/	SYM
admet-801	62	17	min	min	NOUN
admet-801	62	18	was	be	AUX
admet-801	62	19	tested	test	VERB
admet-801	62	20	.	.	PUNCT
admet-801	63	1	the	the	DET
admet-801	63	2	dissolution	dissolution	NOUN
admet-801	63	3	media	medium	NOUN
admet-801	63	4	also	also	ADV
admet-801	63	5	comprised	comprise	VERB
admet-801	63	6	0.1	0.1	NUM
admet-801	63	7	m	m	PROPN
admet-801	63	8	hydrochloric	hydrochloric	ADJ
admet-801	63	9	acid	acid	NOUN
admet-801	63	10	,	,	PUNCT
admet-801	63	11	acetate	acetate	NOUN
admet-801	63	12	buffer	buffer	NOUN
admet-801	63	13	(	(	PUNCT
admet-801	63	14	ph	ph	NOUN
admet-801	63	15	4.5	4.5	NUM
admet-801	63	16	)	)	PUNCT
admet-801	63	17	,	,	PUNCT
admet-801	63	18	and	and	CCONJ
admet-801	63	19	phosphate	phosphate	ADJ
admet-801	63	20	buffer	buffer	NOUN
admet-801	63	21	(	(	PUNCT
admet-801	63	22	ph	ph	NOUN
admet-801	63	23	6.8	6.8	NUM
admet-801	63	24	)	)	PUNCT
admet-801	63	25	at	at	ADP
admet-801	63	26	37.0	37.0	NUM
admet-801	63	27	±	±	NUM
admet-801	63	28	0.5	0.5	NUM
admet-801	63	29	°	°	ADP
admet-801	63	30	c	c	NOUN
admet-801	63	31	.	.	PUNCT
admet-801	64	1	samples	sample	NOUN
admet-801	64	2	were	be	AUX
admet-801	64	3	taken	take	VERB
admet-801	64	4	automatically	automatically	ADV
admet-801	64	5	every	every	DET
admet-801	64	6	5	5	NUM
admet-801	64	7	min	min	NOUN
admet-801	64	8	for	for	ADP
admet-801	64	9	60	60	NUM
admet-801	64	10	min	min	NOUN
admet-801	64	11	.	.	PROPN
admet-801	64	12	dissolved	dissolve	VERB
admet-801	64	13	furosemide	furosemide	NOUN
admet-801	64	14	was	be	AUX
admet-801	64	15	quantified	quantify	VERB
admet-801	64	16	in	in	ADP
admet-801	64	17	a	a	DET
admet-801	64	18	uv	uv	NOUN
admet-801	64	19	/	/	SYM
admet-801	64	20	vis	vis	X
admet-801	64	21	spectrophotometer	spectrophotometer	X
admet-801	64	22	(	(	PUNCT
admet-801	64	23	model	model	NOUN
admet-801	64	24	lambda	lambda	NOUN
admet-801	64	25	10	10	NUM
admet-801	64	26	,	,	PUNCT
admet-801	64	27	perkin	perkin	PROPN
admet-801	64	28	elmer	elmer	PROPN
admet-801	64	29	,	,	PUNCT
admet-801	64	30	usa	usa	PROPN
admet-801	64	31	)	)	PUNCT
admet-801	64	32	with	with	ADP
admet-801	64	33	1	1	NUM
admet-801	64	34	mm	mm	NOUN
admet-801	64	35	cells	cell	NOUN
admet-801	64	36	at	at	ADP
admet-801	64	37	274	274	NUM
admet-801	64	38	nm	nm	NOUN
admet-801	64	39	.	.	PUNCT
admet-801	65	1	for	for	ADP
admet-801	65	2	every	every	DET
admet-801	65	3	trial	trial	NOUN
admet-801	65	4	,	,	PUNCT
admet-801	65	5	and	and	CCONJ
admet-801	65	6	depending	depend	VERB
admet-801	65	7	on	on	ADP
admet-801	65	8	the	the	DET
admet-801	65	9	schedule	schedule	NOUN
admet-801	65	10	work	work	NOUN
admet-801	65	11	,	,	PUNCT
admet-801	65	12	a	a	DET
admet-801	65	13	standard	standard	ADJ
admet-801	65	14	calibration	calibration	NOUN
admet-801	65	15	curve	curve	NOUN
admet-801	65	16	in	in	ADP
admet-801	65	17	0.1	0.1	NUM
admet-801	65	18	n	n	DET
admet-801	65	19	hydrochloric	hydrochloric	ADJ
admet-801	65	20	acid	acid	NOUN
admet-801	65	21	,	,	PUNCT
admet-801	65	22	acetate	acetate	NOUN
admet-801	65	23	buffer	buffer	NOUN
admet-801	65	24	(	(	PUNCT
admet-801	65	25	ph	ph	NOUN
admet-801	65	26	4.5	4.5	NUM
admet-801	65	27	)	)	PUNCT
admet-801	65	28	or	or	CCONJ
admet-801	65	29	phosphate	phosphate	ADJ
admet-801	65	30	buffer	buffer	NOUN
admet-801	65	31	(	(	PUNCT
admet-801	65	32	ph	ph	NOUN
admet-801	65	33	6.8	6.8	NUM
admet-801	65	34	)	)	PUNCT
admet-801	65	35	was	be	AUX
admet-801	65	36	prepared	prepare	VERB
admet-801	65	37	.	.	PUNCT
admet-801	66	1	dissolution	dissolution	PROPN
admet-801	66	2	data	data	PROPN
admet-801	66	3	analysis	analysis	NOUN
admet-801	66	4	dissolution	dissolution	NOUN
admet-801	66	5	profiles	profile	NOUN
admet-801	66	6	were	be	AUX
admet-801	66	7	compared	compare	VERB
admet-801	66	8	with	with	ADP
admet-801	66	9	model	model	NOUN
admet-801	66	10	-	-	PUNCT
admet-801	66	11	independent	independent	ADJ
admet-801	66	12	and	and	CCONJ
admet-801	66	13	model	model	NOUN
admet-801	66	14	-	-	PUNCT
admet-801	66	15	dependent	dependent	ADJ
admet-801	66	16	approaches	approach	NOUN
admet-801	66	17	.	.	PUNCT
admet-801	67	1	for	for	ADP
admet-801	67	2	model	model	NOUN
admet-801	67	3	-	-	PUNCT
admet-801	67	4	independent	independent	ADJ
admet-801	67	5	comparisons	comparison	NOUN
admet-801	67	6	,	,	PUNCT
admet-801	67	7	mean	mean	VERB
admet-801	67	8	dissolution	dissolution	ADJ
admet-801	67	9	time	time	NOUN
admet-801	67	10	(	(	PUNCT
admet-801	67	11	mdt	mdt	PROPN
admet-801	67	12	)	)	PUNCT
admet-801	67	13	and	and	CCONJ
admet-801	67	14	dissolution	dissolution	NOUN
admet-801	67	15	efficiency	efficiency	NOUN
admet-801	67	16	(	(	PUNCT
admet-801	67	17	de	de	ADJ
admet-801	67	18	)	)	PUNCT
admet-801	67	19	were	be	AUX
admet-801	67	20	calculated	calculate	VERB
admet-801	67	21	.	.	PUNCT
admet-801	68	1	mdt	mdt	PROPN
admet-801	68	2	is	be	AUX
admet-801	68	3	the	the	DET
admet-801	68	4	time	time	NOUN
admet-801	68	5	to	to	PART
admet-801	68	6	dissolve	dissolve	VERB
admet-801	68	7	63.2	63.2	NUM
admet-801	68	8	%	%	NOUN
admet-801	68	9	of	of	ADP
admet-801	68	10	the	the	DET
admet-801	68	11	drug	drug	NOUN
admet-801	68	12	and	and	CCONJ
admet-801	68	13	was	be	AUX
admet-801	68	14	calculated	calculate	VERB
admet-801	68	15	according	accord	VERB
admet-801	68	16	to	to	ADP
admet-801	68	17	the	the	DET
admet-801	68	18	statistical	statistical	ADJ
admet-801	68	19	moment	moment	NOUN
admet-801	68	20	’s	’s	PART
admet-801	68	21	theory	theory	NOUN
admet-801	69	1	[	[	X
admet-801	69	2	22,23	22,23	NOUN
admet-801	69	3	]	]	X
admet-801	69	4	.	.	PUNCT
admet-801	70	1	other	other	ADJ
admet-801	70	2	authors	author	NOUN
admet-801	70	3	have	have	AUX
admet-801	70	4	indicated	indicate	VERB
admet-801	70	5	the	the	DET
admet-801	70	6	mdt	mdt	PROPN
admet-801	70	7	to	to	PART
admet-801	70	8	be	be	AUX
admet-801	70	9	62–64	62–64	NUM
admet-801	70	10	%	%	NOUN
admet-801	70	11	[	[	X
admet-801	70	12	24	24	NUM
admet-801	70	13	]	]	PUNCT
admet-801	70	14	.	.	PUNCT
admet-801	71	1	de	de	X
admet-801	71	2	is	be	AUX
admet-801	71	3	the	the	DET
admet-801	71	4	area	area	NOUN
admet-801	71	5	under	under	ADP
admet-801	71	6	the	the	DET
admet-801	71	7	dissolution	dissolution	NOUN
admet-801	71	8	curve	curve	NOUN
admet-801	71	9	up	up	ADP
admet-801	71	10	to	to	ADP
admet-801	71	11	a	a	DET
admet-801	71	12	certain	certain	ADJ
admet-801	71	13	time	time	NOUN
admet-801	71	14	,	,	PUNCT
admet-801	71	15	t	t	PROPN
admet-801	71	16	,	,	PUNCT
admet-801	71	17	expressed	express	VERB
admet-801	71	18	as	as	ADP
admet-801	71	19	a	a	DET
admet-801	71	20	percentage	percentage	NOUN
admet-801	71	21	of	of	ADP
admet-801	71	22	the	the	DET
admet-801	71	23	area	area	NOUN
admet-801	71	24	of	of	ADP
admet-801	71	25	the	the	DET
admet-801	71	26	rectangle	rectangle	NOUN
admet-801	71	27	described	describe	VERB
admet-801	71	28	by	by	ADP
admet-801	71	29	100	100	NUM
admet-801	71	30	%	%	NOUN
admet-801	71	31	dissolution	dissolution	NOUN
admet-801	71	32	in	in	ADP
admet-801	71	33	the	the	DET
admet-801	71	34	same	same	ADJ
admet-801	71	35	period	period	NOUN
admet-801	71	36	[	[	X
admet-801	71	37	25	25	NUM
admet-801	71	38	]	]	PUNCT
admet-801	71	39	.	.	PUNCT
admet-801	72	1	both	both	DET
admet-801	72	2	parameters	parameter	NOUN
admet-801	72	3	were	be	AUX
admet-801	72	4	calculated	calculate	VERB
admet-801	72	5	with	with	ADP
admet-801	72	6	the	the	DET
admet-801	72	7	excel	excel	PROPN
admet-801	72	8	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	ADJ
admet-801	72	9	medina	medina	PROPN
admet-801	72	10	-	-	PUNCT
admet-801	72	11	lópez	lópez	PROPN
admet-801	72	12	et	et	PROPN
admet-801	72	13	al	al	PROPN
admet-801	72	14	.	.	PROPN
admet-801	72	15	admet	admet	PROPN
admet-801	72	16	&	&	CCONJ
admet-801	72	17	dmpk	dmpk	PROPN
admet-801	72	18	8(4	8(4	NOUN
admet-801	72	19	)	)	PUNCT
admet-801	72	20	(	(	PUNCT
admet-801	72	21	2020	2020	NUM
admet-801	72	22	)	)	PUNCT
admet-801	72	23	411	411	NUM
admet-801	72	24	-	-	SYM
admet-801	72	25	423	423	NUM
admet-801	72	26	414	414	NUM
admet-801	72	27	add	add	VERB
admet-801	72	28	-	-	PUNCT
admet-801	72	29	in	in	ADP
admet-801	72	30	ddsolver	ddsolver	NOUN
admet-801	72	31	program	program	NOUN
admet-801	72	32	[	[	X
admet-801	72	33	26	26	NUM
admet-801	72	34	]	]	PUNCT
admet-801	72	35	.	.	PUNCT
admet-801	73	1	for	for	ADP
admet-801	73	2	model	model	NOUN
admet-801	73	3	-	-	PUNCT
admet-801	73	4	dependent	dependent	ADJ
admet-801	73	5	comparisons	comparison	NOUN
admet-801	73	6	,	,	PUNCT
admet-801	73	7	dissolution	dissolution	PROPN
admet-801	73	8	data	datum	NOUN
admet-801	73	9	were	be	AUX
admet-801	73	10	adjusted	adjust	VERB
admet-801	73	11	to	to	ADP
admet-801	73	12	a	a	DET
admet-801	73	13	hyperbole	hyperbole	NOUN
admet-801	73	14	equation	equation	NOUN
admet-801	73	15	(	(	PUNCT
admet-801	73	16	y	y	NOUN
admet-801	73	17	=	=	NOUN
admet-801	73	18	ax	ax	NOUN
admet-801	73	19	/	/	SYM
admet-801	73	20	b+x	b+x	NUM
admet-801	73	21	)	)	PUNCT
admet-801	73	22	and	and	CCONJ
admet-801	73	23	,	,	PUNCT
admet-801	73	24	using	use	VERB
admet-801	73	25	a	a	DET
admet-801	73	26	and	and	CCONJ
admet-801	73	27	b	b	NOUN
admet-801	73	28	parameters	parameter	NOUN
admet-801	73	29	,	,	PUNCT
admet-801	73	30	time	time	NOUN
admet-801	73	31	to	to	ADP
admet-801	73	32	50	50	NUM
admet-801	73	33	%	%	NOUN
admet-801	73	34	dissolution	dissolution	NOUN
admet-801	73	35	(	(	PUNCT
admet-801	73	36	t50	t50	NOUN
admet-801	73	37	%	%	NOUN
admet-801	73	38	)	)	PUNCT
admet-801	73	39	and	and	CCONJ
admet-801	73	40	time	time	NOUN
admet-801	73	41	to	to	ADP
admet-801	73	42	80	80	NUM
admet-801	73	43	%	%	NOUN
admet-801	73	44	dissolution	dissolution	NOUN
admet-801	73	45	(	(	PUNCT
admet-801	73	46	t80	t80	PROPN
admet-801	73	47	%	%	NOUN
admet-801	73	48	)	)	PUNCT
admet-801	73	49	were	be	AUX
admet-801	73	50	calculated	calculate	VERB
admet-801	73	51	.	.	PUNCT
admet-801	74	1	the	the	DET
admet-801	74	2	fit	fit	NOUN
admet-801	74	3	was	be	AUX
admet-801	74	4	calculated	calculate	VERB
admet-801	74	5	using	use	VERB
admet-801	74	6	sigmaplot	sigmaplot	ADJ
admet-801	74	7	software	software	NOUN
admet-801	74	8	(	(	PUNCT
admet-801	74	9	version	version	NOUN
admet-801	74	10	11.0	11.0	NUM
admet-801	74	11	)	)	PUNCT
admet-801	74	12	.	.	PUNCT
admet-801	75	1	for	for	ADP
admet-801	75	2	a	a	DET
admet-801	75	3	complete	complete	ADJ
admet-801	75	4	comparison	comparison	NOUN
admet-801	75	5	of	of	ADP
admet-801	75	6	dissolution	dissolution	NOUN
admet-801	75	7	data	datum	NOUN
admet-801	75	8	by	by	ADP
admet-801	75	9	a	a	DET
admet-801	75	10	model	model	ADJ
admet-801	75	11	-	-	PUNCT
admet-801	75	12	dependent	dependent	ADJ
admet-801	75	13	approach	approach	NOUN
admet-801	75	14	,	,	PUNCT
admet-801	75	15	dissolution	dissolution	PROPN
admet-801	75	16	data	datum	NOUN
admet-801	75	17	were	be	AUX
admet-801	75	18	fitted	fit	VERB
admet-801	75	19	to	to	ADP
admet-801	75	20	zero	zero	NUM
admet-801	75	21	-	-	PUNCT
admet-801	75	22	order	order	NOUN
admet-801	75	23	,	,	PUNCT
admet-801	75	24	first	first	ADJ
admet-801	75	25	-	-	PUNCT
admet-801	75	26	order	order	NOUN
admet-801	75	27	,	,	PUNCT
admet-801	75	28	higuchi	higuchi	PROPN
admet-801	75	29	,	,	PUNCT
admet-801	75	30	hixson	hixson	PROPN
admet-801	75	31	-	-	PUNCT
admet-801	75	32	crowell	crowell	PROPN
admet-801	75	33	,	,	PUNCT
admet-801	75	34	makoid	makoid	NOUN
admet-801	75	35	-	-	PUNCT
admet-801	75	36	banakar	banakar	NOUN
admet-801	75	37	,	,	PUNCT
admet-801	75	38	and	and	CCONJ
admet-801	75	39	weibull	weibull	PROPN
admet-801	75	40	models	model	NOUN
admet-801	75	41	.	.	PUNCT
admet-801	76	1	the	the	DET
admet-801	76	2	model	model	NOUN
admet-801	76	3	with	with	ADP
admet-801	76	4	the	the	DET
admet-801	76	5	highest	high	ADJ
admet-801	76	6	adjusted	adjusted	ADJ
admet-801	76	7	determination	determination	NOUN
admet-801	76	8	coefficient	coefficient	NOUN
admet-801	76	9	(	(	PUNCT
admet-801	76	10	r2	r2	PROPN
admet-801	76	11	adjusted	adjust	VERB
admet-801	76	12	)	)	PUNCT
admet-801	76	13	and	and	CCONJ
admet-801	76	14	lowest	low	ADJ
admet-801	76	15	akaike	akaike	ADJ
admet-801	76	16	information	information	NOUN
admet-801	76	17	criterion	criterion	NOUN
admet-801	76	18	(	(	PUNCT
admet-801	76	19	aic	aic	PROPN
admet-801	76	20	)	)	PUNCT
admet-801	76	21	is	be	AUX
admet-801	76	22	the	the	DET
admet-801	76	23	best	good	ADJ
admet-801	76	24	-	-	PUNCT
admet-801	76	25	fit	fit	ADJ
admet-801	76	26	model	model	NOUN
admet-801	76	27	[	[	X
admet-801	76	28	27	27	NUM
admet-801	76	29	]	]	PUNCT
admet-801	76	30	.	.	PUNCT
admet-801	77	1	data	datum	NOUN
admet-801	77	2	analysis	analysis	NOUN
admet-801	77	3	was	be	AUX
admet-801	77	4	carried	carry	VERB
admet-801	77	5	out	out	ADP
admet-801	77	6	using	use	VERB
admet-801	77	7	excel	excel	NOUN
admet-801	77	8	add	add	VERB
admet-801	77	9	-	-	PUNCT
admet-801	77	10	in	in	ADP
admet-801	77	11	ddsolver	ddsolver	NOUN
admet-801	77	12	program	program	NOUN
admet-801	77	13	[	[	X
admet-801	77	14	28	28	NUM
admet-801	77	15	]	]	PUNCT
admet-801	77	16	.	.	PUNCT
admet-801	78	1	all	all	DET
admet-801	78	2	statistical	statistical	ADJ
admet-801	78	3	comparisons	comparison	NOUN
admet-801	78	4	were	be	AUX
admet-801	78	5	carried	carry	VERB
admet-801	78	6	out	out	ADP
admet-801	78	7	with	with	ADP
admet-801	78	8	student	student	NOUN
admet-801	78	9	’s	’s	PART
admet-801	78	10	t	t	PROPN
admet-801	78	11	-	-	PUNCT
admet-801	78	12	tests	test	NOUN
admet-801	78	13	with	with	ADP
admet-801	78	14	significant	significant	ADJ
admet-801	78	15	differences	difference	NOUN
admet-801	78	16	at	at	ADP
admet-801	78	17	p	p	X
admet-801	78	18	<	<	X
admet-801	78	19	0.05	0.05	NUM
admet-801	78	20	.	.	PUNCT
admet-801	79	1	results	result	NOUN
admet-801	79	2	content	content	NOUN
admet-801	79	3	uniformity	uniformity	NOUN
admet-801	79	4	and	and	CCONJ
admet-801	79	5	assay	assay	VERB
admet-801	79	6	the	the	DET
admet-801	79	7	drug	drug	NOUN
admet-801	79	8	product	product	NOUN
admet-801	79	9	used	use	VERB
admet-801	79	10	met	meet	VERB
admet-801	79	11	the	the	DET
admet-801	79	12	content	content	NOUN
admet-801	79	13	uniformity	uniformity	NOUN
admet-801	79	14	and	and	CCONJ
admet-801	79	15	assay	assay	NOUN
admet-801	79	16	tests	test	NOUN
admet-801	79	17	specified	specify	VERB
admet-801	79	18	in	in	ADP
admet-801	79	19	the	the	DET
admet-801	79	20	usp	usp	NOUN
admet-801	79	21	.	.	PUNCT
admet-801	80	1	the	the	DET
admet-801	80	2	percentage	percentage	NOUN
admet-801	80	3	of	of	ADP
admet-801	80	4	furosemide	furosemide	NOUN
admet-801	80	5	in	in	ADP
admet-801	80	6	the	the	DET
admet-801	80	7	content	content	NOUN
admet-801	80	8	uniformity	uniformity	NOUN
admet-801	80	9	test	test	NOUN
admet-801	80	10	ranged	range	VERB
admet-801	80	11	from	from	ADP
admet-801	80	12	97.4–100.31	97.4–100.31	PROPN
admet-801	80	13	%	%	NOUN
admet-801	80	14	(	(	PUNCT
admet-801	80	15	pharmacopoeial	pharmacopoeial	ADJ
admet-801	80	16	criteria	criterion	NOUN
admet-801	80	17	,	,	PUNCT
admet-801	80	18	85–115	85–115	PROPN
admet-801	80	19	%	%	NOUN
admet-801	80	20	)	)	PUNCT
admet-801	80	21	and	and	CCONJ
admet-801	80	22	that	that	SCONJ
admet-801	80	23	in	in	ADP
admet-801	80	24	the	the	DET
admet-801	80	25	assay	assay	NOUN
admet-801	80	26	test	test	NOUN
admet-801	80	27	was	be	AUX
admet-801	80	28	100.79	100.79	NUM
admet-801	80	29	%	%	NOUN
admet-801	80	30	(	(	PUNCT
admet-801	80	31	criteria	criterion	NOUN
admet-801	80	32	,	,	PUNCT
admet-801	80	33	90–110	90–110	PROPN
admet-801	80	34	%	%	NOUN
admet-801	80	35	)	)	PUNCT
admet-801	81	1	[	[	X
admet-801	81	2	12	12	NUM
admet-801	81	3	]	]	PUNCT
admet-801	81	4	.	.	PUNCT
admet-801	82	1	dissolution	dissolution	PROPN
admet-801	82	2	profiles	profile	NOUN
admet-801	82	3	with	with	ADP
admet-801	82	4	usp	usp	NOUN
admet-801	82	5	basket	basket	NOUN
admet-801	82	6	and	and	CCONJ
admet-801	82	7	paddle	paddle	NOUN
admet-801	82	8	apparatus	apparatus	NOUN
admet-801	82	9	dissolution	dissolution	NOUN
admet-801	82	10	profiles	profile	NOUN
admet-801	82	11	of	of	ADP
admet-801	82	12	furosemide	furosemide	ADV
admet-801	82	13	obtained	obtain	VERB
admet-801	82	14	with	with	ADP
admet-801	82	15	the	the	DET
admet-801	82	16	usp	usp	PROPN
admet-801	82	17	apparatuses	apparatus	NOUN
admet-801	82	18	1	1	NUM
admet-801	82	19	and	and	CCONJ
admet-801	82	20	2	2	NUM
admet-801	82	21	at	at	ADP
admet-801	82	22	different	different	ADJ
admet-801	82	23	agitation	agitation	NOUN
admet-801	82	24	rates	rate	NOUN
admet-801	82	25	and	and	CCONJ
admet-801	82	26	in	in	ADP
admet-801	82	27	different	different	ADJ
admet-801	82	28	dissolution	dissolution	NOUN
admet-801	82	29	media	medium	NOUN
admet-801	82	30	are	be	AUX
admet-801	82	31	shown	show	VERB
admet-801	82	32	in	in	ADP
admet-801	82	33	figure	figure	NOUN
admet-801	82	34	2	2	NUM
admet-801	82	35	.	.	PUNCT
admet-801	82	36	a	a	DET
admet-801	82	37	limited	limited	ADJ
admet-801	82	38	amount	amount	NOUN
admet-801	82	39	of	of	ADP
admet-801	82	40	furosemide	furosemide	ADJ
admet-801	82	41	dissolved	dissolve	VERB
admet-801	82	42	in	in	ADP
admet-801	82	43	0.1	0.1	NUM
admet-801	82	44	m	m	PROPN
admet-801	82	45	hydrochloric	hydrochloric	ADJ
admet-801	82	46	acid	acid	NOUN
admet-801	82	47	at	at	ADP
admet-801	82	48	60	60	NUM
admet-801	82	49	min	min	NOUN
admet-801	82	50	with	with	ADP
admet-801	82	51	both	both	DET
admet-801	82	52	usp	usp	NOUN
admet-801	82	53	dissolution	dissolution	NOUN
admet-801	82	54	apparatuses	apparatus	NOUN
admet-801	82	55	(	(	PUNCT
admet-801	82	56	<	<	X
admet-801	82	57	20	20	NUM
admet-801	82	58	%	%	NOUN
admet-801	82	59	)	)	PUNCT
admet-801	82	60	.	.	PUNCT
admet-801	83	1	almost	almost	ADV
admet-801	83	2	60	60	NUM
admet-801	83	3	%	%	NOUN
admet-801	83	4	of	of	ADP
admet-801	83	5	the	the	DET
admet-801	83	6	drug	drug	NOUN
admet-801	83	7	dissolved	dissolve	VERB
admet-801	83	8	using	use	VERB
admet-801	83	9	usp	usp	NOUN
admet-801	83	10	apparatus	apparatus	NOUN
admet-801	83	11	2	2	NUM
admet-801	83	12	at	at	ADP
admet-801	83	13	75	75	NUM
admet-801	83	14	rpm	rpm	NOUN
admet-801	83	15	with	with	ADP
admet-801	83	16	acetate	acetate	NOUN
admet-801	83	17	buffer	buffer	NOUN
admet-801	83	18	(	(	PUNCT
admet-801	83	19	ph	ph	NOUN
admet-801	83	20	4.5	4.5	NUM
admet-801	83	21	)	)	PUNCT
admet-801	83	22	as	as	ADP
admet-801	83	23	the	the	DET
admet-801	83	24	dissolution	dissolution	PROPN
admet-801	83	25	medium	medium	NOUN
admet-801	83	26	.	.	PUNCT
admet-801	84	1	a	a	DET
admet-801	84	2	complete	complete	ADJ
admet-801	84	3	release	release	NOUN
admet-801	84	4	of	of	ADP
admet-801	84	5	the	the	DET
admet-801	84	6	drug	drug	NOUN
admet-801	84	7	was	be	AUX
admet-801	84	8	achieved	achieve	VERB
admet-801	84	9	using	use	VERB
admet-801	84	10	phosphate	phosphate	NOUN
admet-801	84	11	buffer	buffer	NOUN
admet-801	84	12	(	(	PUNCT
admet-801	84	13	ph	ph	NOUN
admet-801	84	14	6.8	6.8	NUM
admet-801	84	15	)	)	PUNCT
admet-801	84	16	at	at	ADP
admet-801	84	17	50	50	NUM
admet-801	84	18	and	and	CCONJ
admet-801	84	19	75	75	NUM
admet-801	84	20	rpm	rpm	NOUN
admet-801	84	21	,	,	PUNCT
admet-801	84	22	independent	independent	ADJ
admet-801	84	23	of	of	ADP
admet-801	84	24	the	the	DET
admet-801	84	25	usp	usp	NOUN
admet-801	84	26	apparatus	apparatus	NOUN
admet-801	84	27	used	use	VERB
admet-801	84	28	.	.	PUNCT
admet-801	85	1	to	to	PART
admet-801	85	2	compare	compare	VERB
admet-801	85	3	dissolution	dissolution	ADJ
admet-801	85	4	profiles	profile	NOUN
admet-801	85	5	between	between	ADP
admet-801	85	6	usp	usp	NOUN
admet-801	85	7	apparatuses	apparatus	NOUN
admet-801	85	8	1	1	NUM
admet-801	85	9	and	and	CCONJ
admet-801	85	10	2	2	NUM
admet-801	85	11	,	,	PUNCT
admet-801	85	12	model	model	NOUN
admet-801	85	13	-	-	ADJ
admet-801	85	14	independent	independent	ADJ
admet-801	85	15	and	and	CCONJ
admet-801	85	16	-dependent	-dependent	ADJ
admet-801	85	17	parameters	parameter	NOUN
admet-801	85	18	,	,	PUNCT
admet-801	85	19	at	at	ADP
admet-801	85	20	ph	ph	PROPN
admet-801	85	21	6.8	6.8	NUM
admet-801	85	22	,	,	PUNCT
admet-801	85	23	were	be	AUX
admet-801	85	24	calculated	calculate	VERB
admet-801	85	25	,	,	PUNCT
admet-801	85	26	the	the	DET
admet-801	85	27	results	result	NOUN
admet-801	85	28	of	of	ADP
admet-801	85	29	which	which	PRON
admet-801	85	30	are	be	AUX
admet-801	85	31	shown	show	VERB
admet-801	85	32	in	in	ADP
admet-801	85	33	table	table	NOUN
admet-801	85	34	1	1	NUM
admet-801	85	35	.	.	PUNCT
admet-801	86	1	at	at	ADP
admet-801	86	2	25	25	NUM
admet-801	86	3	rpm	rpm	NOUN
admet-801	86	4	and	and	CCONJ
admet-801	86	5	with	with	ADP
admet-801	86	6	both	both	DET
admet-801	86	7	usp	usp	PROPN
admet-801	86	8	apparatuses	apparatus	NOUN
admet-801	86	9	,	,	PUNCT
admet-801	86	10	less	less	ADJ
admet-801	86	11	than	than	ADP
admet-801	86	12	65	65	NUM
admet-801	86	13	%	%	NOUN
admet-801	86	14	of	of	ADP
admet-801	86	15	furosemide	furosemide	ADJ
admet-801	86	16	dissolved	dissolve	VERB
admet-801	86	17	;	;	PUNCT
admet-801	86	18	thus	thus	ADV
admet-801	86	19	,	,	PUNCT
admet-801	86	20	the	the	DET
admet-801	86	21	t80	t80	PROPN
admet-801	86	22	%	%	NOUN
admet-801	86	23	was	be	AUX
admet-801	86	24	not	not	PART
admet-801	86	25	calculated	calculate	VERB
admet-801	86	26	.	.	PUNCT
admet-801	87	1	at	at	ADP
admet-801	87	2	this	this	DET
admet-801	87	3	agitation	agitation	NOUN
admet-801	87	4	rate	rate	NOUN
admet-801	87	5	,	,	PUNCT
admet-801	87	6	significant	significant	ADJ
admet-801	87	7	differences	difference	NOUN
admet-801	87	8	in	in	ADP
admet-801	87	9	mdt	mdt	PROPN
admet-801	87	10	values	value	NOUN
admet-801	87	11	were	be	AUX
admet-801	87	12	observed	observe	VERB
admet-801	87	13	(	(	PUNCT
admet-801	87	14	p	p	X
admet-801	87	15	<	<	X
admet-801	87	16	0.05	0.05	NUM
admet-801	87	17	)	)	PUNCT
admet-801	87	18	.	.	PUNCT
admet-801	88	1	at	at	ADP
admet-801	88	2	50	50	NUM
admet-801	88	3	rpm	rpm	NOUN
admet-801	88	4	,	,	PUNCT
admet-801	88	5	significant	significant	ADJ
admet-801	88	6	differences	difference	NOUN
admet-801	88	7	in	in	ADP
admet-801	88	8	all	all	DET
admet-801	88	9	calculated	calculated	ADJ
admet-801	88	10	parameters	parameter	NOUN
admet-801	88	11	were	be	AUX
admet-801	88	12	observed	observe	VERB
admet-801	88	13	(	(	PUNCT
admet-801	88	14	p	p	X
admet-801	88	15	<	<	X
admet-801	88	16	0.05	0.05	NUM
admet-801	88	17	)	)	PUNCT
admet-801	88	18	.	.	PUNCT
admet-801	89	1	these	these	DET
admet-801	89	2	results	result	NOUN
admet-801	89	3	suggest	suggest	VERB
admet-801	89	4	a	a	DET
admet-801	89	5	complete	complete	ADJ
admet-801	89	6	non	non	NOUN
admet-801	89	7	-	-	NOUN
admet-801	89	8	equivalence	equivalence	NOUN
admet-801	89	9	in	in	ADP
admet-801	89	10	the	the	DET
admet-801	89	11	dissolution	dissolution	NOUN
admet-801	89	12	performance	performance	NOUN
admet-801	89	13	of	of	ADP
admet-801	89	14	furosemide	furosemide	NOUN
admet-801	89	15	between	between	ADP
admet-801	89	16	usp	usp	NOUN
admet-801	89	17	apparatuses	apparatuse	VERB
admet-801	89	18	1	1	NUM
admet-801	89	19	and	and	CCONJ
admet-801	89	20	2	2	NUM
admet-801	89	21	at	at	ADP
admet-801	89	22	these	these	DET
admet-801	89	23	conditions	condition	NOUN
admet-801	89	24	(	(	PUNCT
admet-801	89	25	ph	ph	NOUN
admet-801	89	26	6.8	6.8	NUM
admet-801	89	27	and	and	CCONJ
admet-801	89	28	50	50	NUM
admet-801	89	29	rpm	rpm	NOUN
admet-801	89	30	)	)	PUNCT
admet-801	89	31	.	.	PUNCT
admet-801	90	1	at	at	ADP
admet-801	90	2	75	75	NUM
admet-801	90	3	rpm	rpm	NOUN
admet-801	90	4	,	,	PUNCT
admet-801	90	5	significant	significant	ADJ
admet-801	90	6	differences	difference	NOUN
admet-801	90	7	in	in	ADP
admet-801	90	8	mdt	mdt	PROPN
admet-801	90	9	,	,	PUNCT
admet-801	90	10	de	de	PROPN
admet-801	90	11	,	,	PUNCT
admet-801	90	12	t50	t50	NOUN
admet-801	90	13	%	%	NOUN
admet-801	90	14	,	,	PUNCT
admet-801	90	15	and	and	CCONJ
admet-801	90	16	t80	t80	PROPN
admet-801	90	17	%	%	NOUN
admet-801	90	18	values	value	NOUN
admet-801	90	19	were	be	AUX
admet-801	90	20	observed	observe	VERB
admet-801	90	21	(	(	PUNCT
admet-801	90	22	p	p	X
admet-801	90	23	<	<	X
admet-801	90	24	0.05	0.05	NUM
admet-801	90	25	)	)	PUNCT
admet-801	90	26	.	.	PUNCT
admet-801	91	1	higher	high	ADJ
admet-801	91	2	values	value	NOUN
admet-801	91	3	of	of	ADP
admet-801	91	4	mdt	mdt	PROPN
admet-801	91	5	,	,	PUNCT
admet-801	91	6	t50	t50	NOUN
admet-801	91	7	%	%	NOUN
admet-801	91	8	,	,	PUNCT
admet-801	91	9	and	and	CCONJ
admet-801	91	10	t80	t80	PROPN
admet-801	91	11	%	%	NOUN
admet-801	91	12	were	be	AUX
admet-801	91	13	observed	observe	VERB
admet-801	91	14	with	with	ADP
admet-801	91	15	usp	usp	NOUN
admet-801	91	16	apparatus	apparatus	NOUN
admet-801	91	17	1	1	NUM
admet-801	91	18	than	than	ADP
admet-801	91	19	with	with	ADP
admet-801	91	20	usp	usp	NOUN
admet-801	91	21	apparatus	apparatus	NOUN
admet-801	91	22	2	2	NUM
admet-801	91	23	,	,	PUNCT
admet-801	91	24	at	at	ADP
admet-801	91	25	50	50	NUM
admet-801	91	26	and	and	CCONJ
admet-801	91	27	75	75	NUM
admet-801	91	28	rpm	rpm	NOUN
admet-801	91	29	;	;	PUNCT
admet-801	91	30	these	these	DET
admet-801	91	31	findings	finding	NOUN
admet-801	91	32	could	could	AUX
admet-801	91	33	be	be	AUX
admet-801	91	34	attributed	attribute	VERB
admet-801	91	35	to	to	ADP
admet-801	91	36	slower	slow	ADJ
admet-801	91	37	in	in	ADP
admet-801	91	38	vitro	vitro	X
admet-801	91	39	dissolution	dissolution	NOUN
admet-801	91	40	rates	rate	NOUN
admet-801	91	41	in	in	ADP
admet-801	91	42	usp	usp	PROPN
admet-801	91	43	apparatus	apparatus	NOUN
admet-801	91	44	1	1	NUM
admet-801	91	45	.	.	PUNCT
admet-801	91	46	dissolution	dissolution	PROPN
admet-801	91	47	data	datum	NOUN
admet-801	91	48	at	at	ADP
admet-801	91	49	ph	ph	PROPN
admet-801	91	50	6.8	6.8	NUM
admet-801	91	51	,	,	PUNCT
admet-801	91	52	adjusted	adjust	VERB
admet-801	91	53	with	with	ADP
admet-801	91	54	different	different	ADJ
admet-801	91	55	mathematical	mathematical	ADJ
admet-801	91	56	models	model	NOUN
admet-801	91	57	,	,	PUNCT
admet-801	91	58	are	be	AUX
admet-801	91	59	shown	show	VERB
admet-801	91	60	in	in	ADP
admet-801	91	61	table	table	NOUN
admet-801	91	62	2	2	NUM
admet-801	91	63	.	.	X
admet-801	91	64	admet	admet	PROPN
admet-801	91	65	&	&	CCONJ
admet-801	91	66	dmpk	dmpk	PROPN
admet-801	91	67	8(4	8(4	NOUN
admet-801	91	68	)	)	PUNCT
admet-801	91	69	(	(	PUNCT
admet-801	91	70	2020	2020	NUM
admet-801	91	71	)	)	PUNCT
admet-801	91	72	411	411	NUM
admet-801	91	73	-	-	SYM
admet-801	91	74	423	423	NUM
admet-801	91	75	in	in	ADP
admet-801	91	76	vitro	vitro	X
admet-801	91	77	release	release	NOUN
admet-801	91	78	studies	study	NOUN
admet-801	91	79	of	of	ADP
admet-801	91	80	furosemide	furosemide	ADJ
admet-801	91	81	doi	doi	NOUN
admet-801	91	82	:	:	PUNCT
admet-801	91	83	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	NOUN
admet-801	91	84	415	415	NUM
admet-801	91	85	figure	figure	NOUN
admet-801	91	86	2	2	NUM
admet-801	91	87	.	.	PUNCT
admet-801	91	88	dissolution	dissolution	ADJ
admet-801	91	89	profiles	profile	NOUN
admet-801	91	90	of	of	ADP
admet-801	91	91	furosemide	furosemide	ADJ
admet-801	91	92	reference	reference	NOUN
admet-801	91	93	tablets	tablet	NOUN
admet-801	91	94	using	use	VERB
admet-801	91	95	usp	usp	NOUN
admet-801	91	96	apparatuses	apparatus	NOUN
admet-801	91	97	1	1	NUM
admet-801	91	98	and	and	CCONJ
admet-801	91	99	2	2	NUM
admet-801	91	100	with	with	ADP
admet-801	91	101	dissolution	dissolution	ADJ
admet-801	91	102	media	medium	NOUN
admet-801	91	103	in	in	ADP
admet-801	91	104	physiological	physiological	ADJ
admet-801	91	105	ph	ph	NOUN
admet-801	91	106	range	range	NOUN
admet-801	91	107	.	.	PUNCT
admet-801	92	1	mean	mean	VERB
admet-801	92	2	,	,	PUNCT
admet-801	92	3	n	n	NOUN
admet-801	92	4	=	=	SYM
admet-801	92	5	6	6	NUM
admet-801	92	6	.	.	PUNCT
admet-801	92	7	table	table	NOUN
admet-801	92	8	1	1	NUM
admet-801	92	9	.	.	PUNCT
admet-801	92	10	model	model	NOUN
admet-801	92	11	-	-	PUNCT
admet-801	92	12	independent	independent	ADJ
admet-801	92	13	and	and	CCONJ
admet-801	92	14	-dependent	-dependent	ADJ
admet-801	92	15	parameters	parameter	NOUN
admet-801	92	16	of	of	ADP
admet-801	92	17	furosemide	furosemide	NOUN
admet-801	92	18	at	at	ADP
admet-801	92	19	ph	ph	PROPN
admet-801	92	20	6.8	6.8	NUM
admet-801	92	21	.	.	PUNCT
admet-801	93	1	mean	mean	PROPN
admet-801	93	2	±	±	NUM
admet-801	93	3	sem	sem	PROPN
admet-801	93	4	,	,	PUNCT
admet-801	93	5	n	n	NOUN
admet-801	93	6	=	=	SYM
admet-801	93	7	6	6	NUM
admet-801	93	8	.	.	PUNCT
admet-801	93	9	agitation	agitation	NOUN
admet-801	93	10	rate	rate	NOUN
admet-801	93	11	(	(	PUNCT
admet-801	93	12	rpm	rpm	PROPN
admet-801	93	13	)	)	PUNCT
admet-801	93	14	parameter	parameter	NOUN
admet-801	93	15	usp	usp	PROPN
admet-801	93	16	apparatus	apparatus	PROPN
admet-801	93	17	1	1	NUM
admet-801	93	18	usp	usp	NOUN
admet-801	93	19	apparatus	apparatus	NOUN
admet-801	93	20	2	2	NUM
admet-801	93	21	25	25	NUM
admet-801	93	22	diss	diss	NOUN
admet-801	93	23	.	.	PUNCT
admet-801	94	1	at	at	ADP
admet-801	94	2	60	60	NUM
admet-801	94	3	min	min	NOUN
admet-801	94	4	(	(	PUNCT
admet-801	94	5	%	%	INTJ
admet-801	94	6	)	)	PUNCT
admet-801	94	7	64.61	64.61	NUM
admet-801	94	8	±	±	NUM
admet-801	94	9	1.64	1.64	NUM
admet-801	94	10	62.98	62.98	NUM
admet-801	94	11	±	±	NUM
admet-801	94	12	5.87	5.87	NUM
admet-801	94	13	mdt	mdt	PROPN
admet-801	94	14	(	(	PUNCT
admet-801	94	15	min	min	PROPN
admet-801	94	16	)	)	PUNCT
admet-801	94	17	18.94	18.94	NUM
admet-801	94	18	±	±	NUM
admet-801	94	19	0.16	0.16	NUM
admet-801	94	20	17.11	17.11	NUM
admet-801	94	21	±	±	NOUN
admet-801	94	22	0.42	0.42	NUM
admet-801	94	23	*	*	PUNCT
admet-801	94	24	de	de	X
admet-801	94	25	(	(	PUNCT
admet-801	94	26	%	%	INTJ
admet-801	94	27	)	)	PUNCT
admet-801	94	28	44.42	44.42	NUM
admet-801	94	29	±	±	NUM
admet-801	94	30	1.18	1.18	NUM
admet-801	94	31	45.15	45.15	NUM
admet-801	94	32	±	±	NUM
admet-801	94	33	4.49	4.49	NUM
admet-801	94	34	t50	t50	NOUN
admet-801	94	35	%	%	NOUN
admet-801	94	36	(	(	PUNCT
admet-801	94	37	min	min	NOUN
admet-801	94	38	)	)	PUNCT
admet-801	94	39	31.09	31.09	NUM
admet-801	94	40	±	±	NUM
admet-801	94	41	1.89	1.89	NUM
admet-801	94	42	33.07	33.07	NUM
admet-801	94	43	±	±	NUM
admet-801	94	44	8.47	8.47	NUM
admet-801	94	45	t80	t80	PROPN
admet-801	94	46	%	%	NOUN
admet-801	94	47	(	(	PUNCT
admet-801	94	48	min	min	NOUN
admet-801	94	49	)	)	PUNCT
admet-801	94	50	†	†	PROPN
admet-801	94	51	†	†	PROPN
admet-801	94	52	50	50	NUM
admet-801	94	53	diss	diss	NOUN
admet-801	94	54	.	.	PUNCT
admet-801	95	1	at	at	ADP
admet-801	95	2	60	60	NUM
admet-801	95	3	min	min	NOUN
admet-801	95	4	(	(	PUNCT
admet-801	95	5	%	%	INTJ
admet-801	95	6	)	)	PUNCT
admet-801	95	7	93.90	93.90	NUM
admet-801	95	8	±	±	NUM
admet-801	95	9	2.23	2.23	NUM
admet-801	95	10	101.76	101.76	NUM
admet-801	95	11	±	±	NUM
admet-801	95	12	0.54	0.54	NUM
admet-801	95	13	*	*	PUNCT
admet-801	95	14	mdt	mdt	PROPN
admet-801	95	15	(	(	PUNCT
admet-801	95	16	min	min	NOUN
admet-801	95	17	)	)	PUNCT
admet-801	95	18	15.00	15.00	NUM
admet-801	95	19	±	±	NUM
admet-801	95	20	0.81	0.81	NUM
admet-801	95	21	4.99	4.99	NUM
admet-801	95	22	±	±	NOUN
admet-801	95	23	0.14	0.14	NUM
admet-801	95	24	*	*	PUNCT
admet-801	95	25	de	de	X
admet-801	95	26	(	(	PUNCT
admet-801	95	27	%	%	INTJ
admet-801	95	28	)	)	PUNCT
admet-801	95	29	70.56	70.56	NUM
admet-801	95	30	±	±	NUM
admet-801	95	31	2.85	2.85	NUM
admet-801	95	32	93.30	93.30	NUM
admet-801	95	33	±	±	NUM
admet-801	95	34	0.43	0.43	NUM
admet-801	95	35	*	*	PUNCT
admet-801	95	36	t50	t50	NUM
admet-801	95	37	%	%	NOUN
admet-801	95	38	(	(	PUNCT
admet-801	95	39	min	min	NOUN
admet-801	95	40	)	)	PUNCT
admet-801	95	41	11.15	11.15	NUM
admet-801	95	42	±	±	NUM
admet-801	95	43	1.35	1.35	NUM
admet-801	95	44	2.07	2.07	NUM
admet-801	95	45	±	±	NOUN
admet-801	95	46	0.11	0.11	NUM
admet-801	95	47	*	*	PUNCT
admet-801	95	48	t80	t80	PROPN
admet-801	95	49	%	%	NOUN
admet-801	95	50	(	(	PUNCT
admet-801	95	51	min	min	NOUN
admet-801	95	52	)	)	PUNCT
admet-801	95	53	32.27	32.27	NUM
admet-801	95	54	±	±	NUM
admet-801	95	55	4.02	4.02	NUM
admet-801	95	56	6.75	6.75	NUM
admet-801	95	57	±	±	NUM
admet-801	95	58	0.30	0.30	NUM
admet-801	95	59	*	*	SYM
admet-801	95	60	75	75	NUM
admet-801	95	61	diss	diss	PROPN
admet-801	95	62	.	.	PUNCT
admet-801	96	1	at	at	ADP
admet-801	96	2	60	60	NUM
admet-801	96	3	min	min	NOUN
admet-801	96	4	(	(	PUNCT
admet-801	96	5	%	%	INTJ
admet-801	96	6	)	)	PUNCT
admet-801	96	7	102.43	102.43	NUM
admet-801	96	8	±	±	NUM
admet-801	96	9	0.30	0.30	NUM
admet-801	96	10	102.02	102.02	NUM
admet-801	96	11	±	±	NUM
admet-801	96	12	0.48	0.48	NUM
admet-801	96	13	mdt	mdt	PROPN
admet-801	96	14	(	(	PUNCT
admet-801	96	15	min	min	NOUN
admet-801	96	16	)	)	PUNCT
admet-801	96	17	7.49	7.49	NUM
admet-801	96	18	±	±	NUM
admet-801	96	19	0.41	0.41	NUM
admet-801	96	20	3.42	3.42	NUM
admet-801	96	21	±	±	NUM
admet-801	96	22	0.01	0.01	NUM
admet-801	96	23	*	*	PUNCT
admet-801	96	24	de	de	X
admet-801	96	25	(	(	PUNCT
admet-801	96	26	%	%	NOUN
admet-801	96	27	)	)	PUNCT
admet-801	96	28	89.64	89.64	NUM
admet-801	96	29	±	±	NUM
admet-801	96	30	0.77	0.77	NUM
admet-801	96	31	96.20	96.20	NUM
admet-801	96	32	±	±	NOUN
admet-801	96	33	0.45	0.45	NUM
admet-801	96	34	*	*	PUNCT
admet-801	96	35	t50	t50	NUM
admet-801	96	36	%	%	NOUN
admet-801	96	37	(	(	PUNCT
admet-801	96	38	min	min	NOUN
admet-801	96	39	)	)	PUNCT
admet-801	96	40	4.13	4.13	NUM
admet-801	96	41	±	±	NUM
admet-801	96	42	0.30	0.30	NUM
admet-801	96	43	0.72	0.72	NUM
admet-801	96	44	±	±	NUM
admet-801	96	45	0.02	0.02	NUM
admet-801	96	46	*	*	PUNCT
admet-801	96	47	t80	t80	PROPN
admet-801	96	48	%	%	NOUN
admet-801	96	49	(	(	PUNCT
admet-801	96	50	min	min	NOUN
admet-801	96	51	)	)	PUNCT
admet-801	96	52	11.95	11.95	NUM
admet-801	96	53	±	±	NUM
admet-801	96	54	0.75	0.75	NUM
admet-801	96	55	2.58	2.58	NUM
admet-801	96	56	±	±	NOUN
admet-801	96	57	0.08	0.08	NUM
admet-801	96	58	*	*	PUNCT
admet-801	96	59	*	*	PUNCT
admet-801	96	60	p	p	X
admet-801	96	61	<	<	X
admet-801	96	62	0.05	0.05	NUM
admet-801	96	63	.	.	PUNCT
admet-801	96	64	†data	†data	ADJ
admet-801	96	65	not	not	PART
admet-801	96	66	calculated	calculate	VERB
admet-801	96	67	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	ADJ
admet-801	96	68	medina	medina	PROPN
admet-801	96	69	-	-	PUNCT
admet-801	96	70	lópez	lópez	PROPN
admet-801	96	71	et	et	PROPN
admet-801	96	72	al	al	PROPN
admet-801	96	73	.	.	PROPN
admet-801	96	74	admet	admet	PROPN
admet-801	96	75	&	&	CCONJ
admet-801	96	76	dmpk	dmpk	PROPN
admet-801	96	77	8(4	8(4	NOUN
admet-801	96	78	)	)	PUNCT
admet-801	96	79	(	(	PUNCT
admet-801	96	80	2020	2020	NUM
admet-801	96	81	)	)	PUNCT
admet-801	96	82	411	411	NUM
admet-801	96	83	-	-	SYM
admet-801	96	84	423	423	NUM
admet-801	96	85	416	416	NUM
admet-801	96	86	table	table	NOUN
admet-801	96	87	2	2	NUM
admet-801	96	88	.	.	PUNCT
admet-801	96	89	criteria	criterion	NOUN
admet-801	96	90	used	use	VERB
admet-801	96	91	for	for	ADP
admet-801	96	92	the	the	DET
admet-801	96	93	selection	selection	NOUN
admet-801	96	94	of	of	ADP
admet-801	96	95	the	the	DET
admet-801	96	96	best	good	ADJ
admet-801	96	97	-	-	PUNCT
admet-801	96	98	fit	fit	ADJ
admet-801	96	99	model	model	NOUN
admet-801	96	100	at	at	ADP
admet-801	96	101	ph	ph	PROPN
admet-801	96	102	6.8	6.8	NUM
admet-801	96	103	.	.	PUNCT
admet-801	97	1	mean	mean	VERB
admet-801	97	2	,	,	PUNCT
admet-801	97	3	n	n	NOUN
admet-801	97	4	=	=	SYM
admet-801	97	5	6	6	NUM
admet-801	97	6	.	.	PUNCT
admet-801	97	7	parameter	parameter	NOUN
admet-801	97	8	agitation	agitation	NOUN
admet-801	97	9	rate	rate	NOUN
admet-801	97	10	(	(	PUNCT
admet-801	97	11	rpm	rpm	NOUN
admet-801	97	12	)	)	PUNCT
admet-801	97	13	zeroorder	zeroorder	NOUN
admet-801	97	14	firstorder	firstorder	NOUN
admet-801	97	15	higuchi	higuchi	PROPN
admet-801	97	16	hixsoncrowell	hixsoncrowell	PROPN
admet-801	97	17	makoidbanakar	makoidbanakar	PROPN
admet-801	97	18	weibull	weibull	PROPN
admet-801	97	19	usp	usp	PROPN
admet-801	97	20	apparatus	apparatus	NOUN
admet-801	97	21	1	1	NUM
admet-801	97	22	r	r	NOUN
admet-801	97	23	2	2	NUM
admet-801	97	24	adjusted	adjust	VERB
admet-801	97	25	25	25	NUM
admet-801	97	26	0.5474	0.5474	NUM
admet-801	98	1	0.8935	0.8935	NUM
admet-801	98	2	0.9731	0.9731	NUM
admet-801	98	3	0.8155	0.8155	NUM
admet-801	98	4	0.9938	0.9938	NUM
admet-801	98	5	0.9997	0.9997	NUM
admet-801	98	6	50	50	NUM
admet-801	98	7	-0.2118	-0.2118	NOUN
admet-801	98	8	0.9725	0.9725	NUM
admet-801	98	9	0.8774	0.8774	NUM
admet-801	98	10	0.8929	0.8929	NUM
admet-801	98	11	0.9932	0.9932	NUM
admet-801	98	12	0.9996	0.9996	NUM
admet-801	98	13	75	75	NUM
admet-801	98	14	-3.99	-3.99	NUM
admet-801	98	15	0.9492	0.9492	NUM
admet-801	98	16	-0.2872	-0.2872	NOUN
admet-801	99	1	0.6144	0.6144	NUM
admet-801	99	2	0.9281	0.9281	NUM
admet-801	99	3	0.9994	0.9994	NUM
admet-801	99	4	aic	aic	PROPN
admet-801	99	5	25	25	NUM
admet-801	99	6	87.76	87.76	NUM
admet-801	99	7	69.95	69.95	NUM
admet-801	99	8	53.49	53.49	NUM
admet-801	99	9	76.81	76.81	NUM
admet-801	99	10	37.07	37.07	NUM
admet-801	99	11	1.85	1.85	NUM
admet-801	99	12	50	50	NUM
admet-801	99	13	104.11	104.11	NUM
admet-801	99	14	56.38	56.38	NUM
admet-801	99	15	74.14	74.14	NUM
admet-801	99	16	74.83	74.83	NUM
admet-801	99	17	42.38	42.38	NUM
admet-801	99	18	8.99	8.99	NUM
admet-801	99	19	75	75	NUM
admet-801	99	20	117.66	117.66	NUM
admet-801	99	21	60.73	60.73	NUM
admet-801	99	22	101.10	101.10	NUM
admet-801	99	23	85.25	85.25	NUM
admet-801	99	24	66.30	66.30	NUM
admet-801	99	25	0.64	0.64	NUM
admet-801	99	26	usp	usp	NOUN
admet-801	99	27	apparatus	apparatus	NOUN
admet-801	99	28	2	2	NUM
admet-801	99	29	r	r	NOUN
admet-801	99	30	2	2	NUM
admet-801	99	31	adjusted	adjust	VERB
admet-801	99	32	25	25	NUM
admet-801	99	33	0.3232	0.3232	NUM
admet-801	99	34	0.7889	0.7889	NUM
admet-801	99	35	0.9521	0.9521	NUM
admet-801	99	36	0.6872	0.6872	NUM
admet-801	99	37	0.9952	0.9952	NUM
admet-801	99	38	0.9976	0.9976	NUM
admet-801	99	39	50	50	NUM
admet-801	99	40	-17.85	-17.85	NOUN
admet-801	99	41	0.9611	0.9611	NUM
admet-801	99	42	0.8774	0.8774	NUM
admet-801	99	43	-1.85	-1.85	NUM
admet-801	99	44	0.9932	0.9932	NUM
admet-801	99	45	0.9999	0.9999	NUM
admet-801	99	46	75	75	NUM
admet-801	99	47	-144.29	-144.29	NOUN
admet-801	99	48	0.7176	0.7176	NUM
admet-801	99	49	-50.97	-50.97	PUNCT
admet-801	99	50	-31.37	-31.37	PUNCT
admet-801	99	51	0.9016	0.9016	PROPN
admet-801	99	52	0.9998	0.9998	NUM
admet-801	99	53	aic	aic	PROPN
admet-801	99	54	25	25	NUM
admet-801	99	55	90.15	90.15	NUM
admet-801	99	56	73.14	73.14	NUM
admet-801	99	57	55.70	55.70	NUM
admet-801	99	58	79.54	79.54	NUM
admet-801	99	59	27.37	27.37	NUM
admet-801	99	60	17.52	17.52	NUM
admet-801	99	61	50	50	NUM
admet-801	99	62	120.96	120.96	NUM
admet-801	99	63	36.84	36.84	NUM
admet-801	99	64	74.14	74.14	NUM
admet-801	99	65	98.05	98.05	NUM
admet-801	99	66	42.38	42.38	NUM
admet-801	99	67	-34.36	-34.36	NOUN
admet-801	99	68	75	75	NUM
admet-801	99	69	123.27	123.27	NUM
admet-801	99	70	42.04	42.04	NUM
admet-801	99	71	110.92	110.92	NUM
admet-801	99	72	105.23	105.23	NUM
admet-801	99	73	37.35	37.35	NUM
admet-801	99	74	-40.46	-40.46	PUNCT
admet-801	99	75	considering	consider	VERB
admet-801	99	76	the	the	DET
admet-801	99	77	established	establish	VERB
admet-801	99	78	criteria	criterion	NOUN
admet-801	99	79	to	to	PART
admet-801	99	80	choose	choose	VERB
admet-801	99	81	the	the	DET
admet-801	99	82	best	good	ADJ
admet-801	99	83	-	-	PUNCT
admet-801	99	84	fit	fit	ADJ
admet-801	99	85	model	model	NOUN
admet-801	99	86	(	(	PUNCT
admet-801	99	87	higher	high	ADJ
admet-801	99	88	r2	r2	PROPN
admet-801	99	89	adjusted	adjust	VERB
admet-801	99	90	and	and	CCONJ
admet-801	99	91	lower	low	ADJ
admet-801	99	92	aic	aic	PROPN
admet-801	99	93	values	value	NOUN
admet-801	99	94	)	)	PUNCT
admet-801	99	95	,	,	PUNCT
admet-801	99	96	the	the	DET
admet-801	99	97	weibull	weibull	PROPN
admet-801	99	98	function	function	NOUN
admet-801	99	99	was	be	AUX
admet-801	99	100	the	the	DET
admet-801	99	101	best	good	ADJ
admet-801	99	102	mathematical	mathematical	ADJ
admet-801	99	103	equation	equation	NOUN
admet-801	99	104	to	to	PART
admet-801	99	105	describe	describe	VERB
admet-801	99	106	all	all	DET
admet-801	99	107	dissolution	dissolution	ADJ
admet-801	99	108	data	datum	NOUN
admet-801	99	109	at	at	ADP
admet-801	99	110	ph	ph	PROPN
admet-801	99	111	6.8	6.8	NUM
admet-801	99	112	.	.	PUNCT
admet-801	100	1	the	the	DET
admet-801	100	2	expression	expression	NOUN
admet-801	100	3	of	of	ADP
admet-801	100	4	this	this	DET
admet-801	100	5	function	function	NOUN
admet-801	100	6	is	be	AUX
admet-801	100	7	as	as	SCONJ
admet-801	100	8	follows	follow	VERB
admet-801	100	9	[	[	X
admet-801	100	10	26	26	NUM
admet-801	100	11	]	]	X
admet-801	100	12	:	:	PUNCT
admet-801	100	13	𝐹	𝐹	PROPN
admet-801	100	14	=	=	SYM
admet-801	101	1	𝐹max	𝐹max	PROPN
admet-801	102	1	[	[	X
admet-801	102	2	𝑒	𝑒	X
admet-801	102	3	−	−	PROPN
admet-801	102	4	(	(	PUNCT
admet-801	102	5	𝑡−𝑇𝑖)𝛽	𝑡−𝑇𝑖)𝛽	NOUN
admet-801	102	6	𝛼	𝛼	NOUN
admet-801	102	7	]	]	PUNCT
admet-801	102	8	,	,	PUNCT
admet-801	102	9	(	(	PUNCT
admet-801	102	10	1	1	X
admet-801	102	11	)	)	PUNCT
admet-801	102	12	where	where	SCONJ
admet-801	102	13	f	f	PROPN
admet-801	102	14	is	be	AUX
admet-801	102	15	the	the	DET
admet-801	102	16	percent	percent	NOUN
admet-801	102	17	of	of	ADP
admet-801	102	18	the	the	DET
admet-801	102	19	drug	drug	NOUN
admet-801	102	20	that	that	PRON
admet-801	102	21	dissolved	dissolve	VERB
admet-801	102	22	vs.	vs.	ADP
admet-801	102	23	t	t	PROPN
admet-801	102	24	time	time	NOUN
admet-801	102	25	,	,	PUNCT
admet-801	102	26	fmax	fmax	PROPN
admet-801	102	27	is	be	AUX
admet-801	102	28	the	the	DET
admet-801	102	29	maximum	maximum	ADJ
admet-801	102	30	percent	percent	NOUN
admet-801	102	31	of	of	ADP
admet-801	102	32	the	the	DET
admet-801	102	33	drug	drug	NOUN
admet-801	102	34	that	that	PRON
admet-801	102	35	dissolved	dissolve	VERB
admet-801	102	36	at	at	ADP
admet-801	102	37	infinite	infinite	ADJ
admet-801	102	38	time	time	NOUN
admet-801	102	39	,	,	PUNCT
admet-801	102	40	α	α	PROPN
admet-801	102	41	is	be	AUX
admet-801	102	42	the	the	DET
admet-801	102	43	scale	scale	NOUN
admet-801	102	44	factor	factor	NOUN
admet-801	102	45	of	of	ADP
admet-801	102	46	the	the	DET
admet-801	102	47	process	process	NOUN
admet-801	102	48	,	,	PUNCT
admet-801	102	49	β	β	X
admet-801	102	50	is	be	AUX
admet-801	102	51	the	the	DET
admet-801	102	52	shape	shape	NOUN
admet-801	102	53	factor	factor	NOUN
admet-801	102	54	,	,	PUNCT
admet-801	102	55	and	and	CCONJ
admet-801	102	56	ti	ti	NOUN
admet-801	102	57	is	be	AUX
admet-801	102	58	a	a	DET
admet-801	102	59	location	location	NOUN
admet-801	102	60	parameter	parameter	NOUN
admet-801	102	61	of	of	ADP
admet-801	102	62	time	time	NOUN
admet-801	102	63	in	in	ADP
admet-801	102	64	which	which	PRON
admet-801	102	65	the	the	DET
admet-801	102	66	drug	drug	NOUN
admet-801	102	67	begins	begin	VERB
admet-801	102	68	to	to	PART
admet-801	102	69	dissolve	dissolve	VERB
admet-801	102	70	.	.	PUNCT
admet-801	103	1	the	the	DET
admet-801	103	2	furosemide	furosemide	ADJ
admet-801	103	3	dissolution	dissolution	PROPN
admet-801	103	4	data	datum	NOUN
admet-801	103	5	of	of	ADP
admet-801	103	6	both	both	DET
admet-801	103	7	usp	usp	NOUN
admet-801	103	8	apparatuses	apparatus	NOUN
admet-801	103	9	adjusted	adjust	VERB
admet-801	103	10	to	to	ADP
admet-801	103	11	the	the	DET
admet-801	103	12	weibull	weibull	PROPN
admet-801	103	13	model	model	PROPN
admet-801	103	14	dissolution	dissolution	PROPN
admet-801	103	15	profiles	profile	NOUN
admet-801	103	16	were	be	AUX
admet-801	103	17	statistically	statistically	ADV
admet-801	103	18	compared	compare	VERB
admet-801	103	19	with	with	ADP
admet-801	103	20	td	td	NOUN
admet-801	103	21	values	value	NOUN
admet-801	103	22	derived	derive	VERB
admet-801	103	23	from	from	ADP
admet-801	103	24	fitting	fitting	ADJ
admet-801	103	25	to	to	ADP
admet-801	103	26	this	this	DET
admet-801	103	27	equation	equation	NOUN
admet-801	103	28	.	.	PUNCT
admet-801	104	1	the	the	DET
admet-801	104	2	td	td	NOUN
admet-801	104	3	value	value	NOUN
admet-801	104	4	represents	represent	VERB
admet-801	104	5	the	the	DET
admet-801	104	6	time	time	NOUN
admet-801	104	7	interval	interval	NOUN
admet-801	104	8	necessary	necessary	ADJ
admet-801	104	9	to	to	PART
admet-801	104	10	dissolve	dissolve	VERB
admet-801	104	11	or	or	CCONJ
admet-801	104	12	release	release	VERB
admet-801	104	13	63.2	63.2	NUM
admet-801	104	14	%	%	NOUN
admet-801	104	15	of	of	ADP
admet-801	104	16	the	the	DET
admet-801	104	17	drug	drug	NOUN
admet-801	104	18	present	present	ADJ
admet-801	104	19	in	in	ADP
admet-801	104	20	the	the	DET
admet-801	104	21	pharmaceutical	pharmaceutical	ADJ
admet-801	104	22	dosage	dosage	NOUN
admet-801	104	23	form	form	NOUN
admet-801	104	24	[	[	X
admet-801	104	25	25	25	NUM
admet-801	104	26	]	]	PUNCT
admet-801	104	27	and	and	CCONJ
admet-801	104	28	coincides	coincide	VERB
admet-801	104	29	with	with	ADP
admet-801	104	30	mdt	mdt	PROPN
admet-801	104	31	if	if	SCONJ
admet-801	104	32	the	the	DET
admet-801	104	33	dissolution	dissolution	ADJ
admet-801	104	34	rate	rate	NOUN
admet-801	104	35	-	-	PUNCT
admet-801	104	36	time	time	NOUN
admet-801	104	37	curve	curve	NOUN
admet-801	104	38	can	can	AUX
admet-801	104	39	be	be	AUX
admet-801	104	40	approximated	approximate	VERB
admet-801	104	41	by	by	ADP
admet-801	104	42	a	a	DET
admet-801	104	43	monoexponential	monoexponential	ADJ
admet-801	104	44	equation	equation	NOUN
admet-801	104	45	[	[	X
admet-801	104	46	22	22	NUM
admet-801	104	47	]	]	PUNCT
admet-801	104	48	.	.	PUNCT
admet-801	105	1	the	the	DET
admet-801	105	2	mean	mean	ADJ
admet-801	105	3	values	value	NOUN
admet-801	105	4	of	of	ADP
admet-801	105	5	α	α	PROPN
admet-801	105	6	,	,	PUNCT
admet-801	105	7	β	β	X
admet-801	105	8	,	,	PUNCT
admet-801	105	9	ti	ti	NOUN
admet-801	105	10	,	,	PUNCT
admet-801	105	11	fmax	fmax	ADJ
admet-801	105	12	,	,	PUNCT
admet-801	105	13	and	and	CCONJ
admet-801	105	14	td	td	NOUN
admet-801	105	15	are	be	AUX
admet-801	105	16	shown	show	VERB
admet-801	105	17	in	in	ADP
admet-801	105	18	table	table	NOUN
admet-801	105	19	3	3	NUM
admet-801	105	20	.	.	PUNCT
admet-801	106	1	significant	significant	ADJ
admet-801	106	2	differences	difference	NOUN
admet-801	106	3	were	be	AUX
admet-801	106	4	observed	observe	VERB
admet-801	106	5	in	in	ADP
admet-801	106	6	all	all	DET
admet-801	106	7	comparisons	comparison	NOUN
admet-801	106	8	(	(	PUNCT
admet-801	106	9	p	p	X
admet-801	106	10	<	<	X
admet-801	106	11	0.05	0.05	NUM
admet-801	106	12	)	)	PUNCT
admet-801	106	13	.	.	PUNCT
admet-801	107	1	table	table	NOUN
admet-801	107	2	3	3	NUM
admet-801	107	3	.	.	PUNCT
admet-801	108	1	weibull	weibull	PROPN
admet-801	108	2	parameters	parameter	NOUN
admet-801	108	3	and	and	CCONJ
admet-801	108	4	td	td	NOUN
admet-801	108	5	values	value	NOUN
admet-801	108	6	at	at	ADP
admet-801	108	7	ph	ph	PROPN
admet-801	108	8	6.8	6.8	NUM
admet-801	108	9	.	.	PUNCT
admet-801	109	1	mean	mean	VERB
admet-801	109	2	,	,	PUNCT
admet-801	109	3	n	n	NOUN
admet-801	109	4	=	=	SYM
admet-801	109	5	6	6	NUM
admet-801	109	6	.	.	PUNCT
admet-801	109	7	agitation	agitation	NOUN
admet-801	109	8	rate	rate	NOUN
admet-801	109	9	(	(	PUNCT
admet-801	109	10	rpm	rpm	PROPN
admet-801	109	11	)	)	PUNCT
admet-801	109	12	α	α	PROPN
admet-801	109	13	β	β	X
admet-801	109	14	ti	ti	X
admet-801	109	15	fmax	fmax	PROPN
admet-801	109	16	td	td	PROPN
admet-801	109	17	±	±	NUM
admet-801	109	18	sem	sem	NOUN
admet-801	109	19	(	(	PUNCT
admet-801	109	20	min	min	NOUN
admet-801	109	21	)	)	PUNCT
admet-801	109	22	usp	usp	NOUN
admet-801	109	23	apparatus	apparatus	NOUN
admet-801	109	24	1	1	NUM
admet-801	109	25	25	25	NUM
admet-801	109	26	10.25	10.25	NUM
admet-801	109	27	0.63	0.63	NUM
admet-801	109	28	3.12	3.12	NUM
admet-801	109	29	95.48	95.48	NUM
admet-801	109	30	50.15	50.15	NUM
admet-801	109	31	±	±	NUM
admet-801	109	32	9.38	9.38	NUM
admet-801	109	33	50	50	NUM
admet-801	109	34	5.81	5.81	NUM
admet-801	109	35	0.59	0.59	NUM
admet-801	109	36	2.70	2.70	NUM
admet-801	109	37	111.03	111.03	NUM
admet-801	109	38	22.78	22.78	NUM
admet-801	109	39	±	±	NUM
admet-801	109	40	3.93	3.93	NUM
admet-801	109	41	75	75	NUM
admet-801	109	42	13.30	13.30	NUM
admet-801	109	43	1.15	1.15	NUM
admet-801	109	44	0.72	0.72	NUM
admet-801	109	45	102.43	102.43	NUM
admet-801	109	46	7.64	7.64	NUM
admet-801	109	47	±	±	NUM
admet-801	109	48	0.43	0.43	NUM
admet-801	109	49	usp	usp	NOUN
admet-801	109	50	apparatus	apparatus	NOUN
admet-801	109	51	2	2	NUM
admet-801	109	52	25	25	NUM
admet-801	109	53	30.04	30.04	NUM
admet-801	109	54	0.94	0.94	NUM
admet-801	109	55	-0.11	-0.11	NUM
admet-801	109	56	70.50	70.50	NUM
admet-801	109	57	25.63	25.63	NUM
admet-801	109	58	±	±	NUM
admet-801	109	59	3.51	3.51	NUM
admet-801	109	60	*	*	NUM
admet-801	109	61	50	50	NUM
admet-801	109	62	2.75	2.75	NUM
admet-801	109	63	0.84	0.84	NUM
admet-801	109	64	1.53	1.53	NUM
admet-801	109	65	101.76	101.76	NUM
admet-801	109	66	4.72	4.72	NUM
admet-801	109	67	±	±	NOUN
admet-801	109	68	0.18	0.18	NUM
admet-801	109	69	*	*	NOUN
admet-801	109	70	75	75	NUM
admet-801	109	71	1.87	1.87	NUM
admet-801	109	72	0.77	0.77	NUM
admet-801	109	73	-0.39	-0.39	NUM
admet-801	109	74	102.03	102.03	NUM
admet-801	109	75	1.80	1.80	NUM
admet-801	109	76	±	±	NUM
admet-801	109	77	0.12	0.12	NUM
admet-801	109	78	*	*	PUNCT
admet-801	110	1	*	*	PUNCT
admet-801	110	2	p	p	X
admet-801	110	3	<	<	X
admet-801	110	4	0.05	0.05	NUM
admet-801	110	5	.	.	PUNCT
admet-801	111	1	model	model	NOUN
admet-801	111	2	-	-	PUNCT
admet-801	111	3	dependent	dependent	ADJ
admet-801	111	4	comparisons	comparison	NOUN
admet-801	111	5	(	(	PUNCT
admet-801	111	6	by	by	ADP
admet-801	111	7	comparing	compare	VERB
admet-801	111	8	td	td	NOUN
admet-801	111	9	values	value	NOUN
admet-801	111	10	)	)	PUNCT
admet-801	111	11	indicated	indicate	VERB
admet-801	111	12	that	that	SCONJ
admet-801	111	13	usp	usp	NOUN
admet-801	111	14	apparatuses	apparatuse	VERB
admet-801	111	15	1	1	NUM
admet-801	111	16	and	and	CCONJ
admet-801	111	17	2	2	NUM
admet-801	111	18	at	at	ADP
admet-801	111	19	50	50	NUM
admet-801	111	20	and	and	CCONJ
admet-801	111	21	75	75	NUM
admet-801	111	22	rpm	rpm	NOUN
admet-801	111	23	generated	generate	VERB
admet-801	111	24	different	different	ADJ
admet-801	111	25	dissolution	dissolution	NOUN
admet-801	111	26	profiles	profile	NOUN
admet-801	111	27	.	.	PUNCT
admet-801	112	1	as	as	SCONJ
admet-801	112	2	both	both	DET
admet-801	112	3	usp	usp	NOUN
admet-801	112	4	dissolution	dissolution	NOUN
admet-801	112	5	apparatuses	apparatus	NOUN
admet-801	112	6	and	and	CCONJ
admet-801	112	7	agitation	agitation	NOUN
admet-801	112	8	rates	rate	NOUN
admet-801	112	9	created	create	VERB
admet-801	112	10	different	different	ADJ
admet-801	112	11	hydrodynamic	hydrodynamic	ADJ
admet-801	112	12	environments	environment	NOUN
admet-801	112	13	,	,	PUNCT
admet-801	112	14	these	these	DET
admet-801	112	15	results	result	NOUN
admet-801	112	16	were	be	AUX
admet-801	112	17	expected	expect	VERB
admet-801	112	18	.	.	PUNCT
admet-801	113	1	dissolution	dissolution	PROPN
admet-801	113	2	profiles	profile	NOUN
admet-801	113	3	with	with	ADP
admet-801	113	4	flow	flow	NOUN
admet-801	113	5	-	-	PUNCT
admet-801	113	6	through	through	ADP
admet-801	113	7	cell	cell	NOUN
admet-801	113	8	method	method	NOUN
admet-801	113	9	dissolution	dissolution	NOUN
admet-801	113	10	profiles	profile	NOUN
admet-801	113	11	of	of	ADP
admet-801	113	12	furosemide	furosemide	ADJ
admet-801	113	13	reference	reference	NOUN
admet-801	113	14	tablets	tablet	NOUN
admet-801	113	15	using	use	VERB
admet-801	113	16	usp	usp	NOUN
admet-801	113	17	apparatus	apparatus	NOUN
admet-801	113	18	4	4	NUM
admet-801	113	19	with	with	ADP
admet-801	113	20	0.1	0.1	NUM
admet-801	113	21	m	m	PROPN
admet-801	113	22	hydrochloric	hydrochloric	ADJ
admet-801	113	23	acid	acid	NOUN
admet-801	113	24	,	,	PUNCT
admet-801	113	25	acetate	acetate	NOUN
admet-801	113	26	buffer	buffer	NOUN
admet-801	113	27	(	(	PUNCT
admet-801	113	28	ph	ph	NOUN
admet-801	113	29	4.5	4.5	NUM
admet-801	113	30	)	)	PUNCT
admet-801	113	31	,	,	PUNCT
admet-801	113	32	phosphate	phosphate	NOUN
admet-801	113	33	buffer	buffer	NOUN
admet-801	113	34	(	(	PUNCT
admet-801	113	35	ph	ph	NOUN
admet-801	113	36	6.8	6.8	NUM
admet-801	113	37	)	)	PUNCT
admet-801	113	38	,	,	PUNCT
admet-801	113	39	and	and	CCONJ
admet-801	113	40	laminar	laminar	ADJ
admet-801	113	41	flow	flow	NOUN
admet-801	113	42	of	of	ADP
admet-801	113	43	16	16	NUM
admet-801	113	44	ml	ml	NOUN
admet-801	113	45	/	/	SYM
admet-801	113	46	min	min	NOUN
admet-801	113	47	are	be	AUX
admet-801	113	48	shown	show	VERB
admet-801	113	49	in	in	ADP
admet-801	113	50	figure	figure	NOUN
admet-801	113	51	3	3	NUM
admet-801	113	52	.	.	PUNCT
admet-801	113	53	admet	admet	PROPN
admet-801	113	54	&	&	CCONJ
admet-801	113	55	dmpk	dmpk	PROPN
admet-801	113	56	8(4	8(4	NOUN
admet-801	113	57	)	)	PUNCT
admet-801	113	58	(	(	PUNCT
admet-801	113	59	2020	2020	NUM
admet-801	113	60	)	)	PUNCT
admet-801	113	61	411	411	NUM
admet-801	113	62	-	-	SYM
admet-801	113	63	423	423	NUM
admet-801	113	64	in	in	ADP
admet-801	113	65	vitro	vitro	X
admet-801	113	66	release	release	NOUN
admet-801	113	67	studies	study	NOUN
admet-801	113	68	of	of	ADP
admet-801	113	69	furosemide	furosemide	ADJ
admet-801	113	70	doi	doi	PROPN
admet-801	113	71	:	:	PUNCT
admet-801	113	72	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	VERB
admet-801	113	73	417	417	NUM
admet-801	113	74	figure	figure	NOUN
admet-801	113	75	3	3	NUM
admet-801	113	76	.	.	PUNCT
admet-801	113	77	dissolution	dissolution	ADJ
admet-801	113	78	profiles	profile	NOUN
admet-801	113	79	of	of	ADP
admet-801	113	80	furosemide	furosemide	ADJ
admet-801	113	81	reference	reference	NOUN
admet-801	113	82	tablets	tablet	NOUN
admet-801	113	83	using	use	VERB
admet-801	113	84	usp	usp	NOUN
admet-801	113	85	apparatus	apparatus	NOUN
admet-801	113	86	4	4	NUM
admet-801	113	87	with	with	ADP
admet-801	113	88	dissolution	dissolution	ADJ
admet-801	113	89	media	medium	NOUN
admet-801	113	90	in	in	ADP
admet-801	113	91	physiological	physiological	ADJ
admet-801	113	92	ph	ph	NOUN
admet-801	113	93	range	range	NOUN
admet-801	113	94	.	.	PUNCT
admet-801	114	1	mean	mean	VERB
admet-801	114	2	±	±	NUM
admet-801	114	3	sd	sd	NOUN
admet-801	114	4	,	,	PUNCT
admet-801	114	5	n	n	NOUN
admet-801	114	6	=	=	NUM
admet-801	114	7	12	12	NUM
admet-801	114	8	.	.	PUNCT
admet-801	115	1	with	with	ADP
admet-801	115	2	the	the	DET
admet-801	115	3	flow	flow	NOUN
admet-801	115	4	-	-	PUNCT
admet-801	115	5	through	through	ADP
admet-801	115	6	cell	cell	NOUN
admet-801	115	7	method	method	NOUN
admet-801	115	8	,	,	PUNCT
admet-801	115	9	less	less	ADJ
admet-801	115	10	than	than	ADP
admet-801	115	11	20	20	NUM
admet-801	115	12	%	%	NOUN
admet-801	115	13	of	of	ADP
admet-801	115	14	furosemide	furosemide	ADJ
admet-801	115	15	dissolved	dissolve	VERB
admet-801	115	16	when	when	SCONJ
admet-801	115	17	0.1	0.1	NUM
admet-801	115	18	m	m	PROPN
admet-801	115	19	hydrochloric	hydrochloric	ADJ
admet-801	115	20	acid	acid	NOUN
admet-801	115	21	and	and	CCONJ
admet-801	115	22	acetate	acetate	NOUN
admet-801	115	23	buffer	buffer	NOUN
admet-801	115	24	(	(	PUNCT
admet-801	115	25	ph	ph	NOUN
admet-801	115	26	4.5	4.5	NUM
admet-801	115	27	)	)	PUNCT
admet-801	115	28	were	be	AUX
admet-801	115	29	used	use	VERB
admet-801	115	30	,	,	PUNCT
admet-801	115	31	whereas	whereas	SCONJ
admet-801	115	32	almost	almost	ADV
admet-801	115	33	90	90	NUM
admet-801	115	34	%	%	NOUN
admet-801	115	35	of	of	ADP
admet-801	115	36	the	the	DET
admet-801	115	37	drug	drug	NOUN
admet-801	115	38	was	be	AUX
admet-801	115	39	released	release	VERB
admet-801	115	40	with	with	ADP
admet-801	115	41	phosphate	phosphate	ADJ
admet-801	115	42	buffer	buffer	NOUN
admet-801	115	43	(	(	PUNCT
admet-801	115	44	ph	ph	NOUN
admet-801	115	45	6.8	6.8	NUM
admet-801	115	46	)	)	PUNCT
admet-801	115	47	.	.	PUNCT
admet-801	116	1	slower	slow	ADJ
admet-801	116	2	dissolution	dissolution	NOUN
admet-801	116	3	rates	rate	NOUN
admet-801	116	4	with	with	ADP
admet-801	116	5	usp	usp	NOUN
admet-801	116	6	apparatus	apparatus	NOUN
admet-801	116	7	4	4	NUM
admet-801	116	8	than	than	ADP
admet-801	116	9	with	with	ADP
admet-801	116	10	usp	usp	NOUN
admet-801	116	11	apparatuses	apparatus	NOUN
admet-801	116	12	1	1	NUM
admet-801	116	13	and	and	CCONJ
admet-801	116	14	2	2	NUM
admet-801	116	15	have	have	AUX
admet-801	116	16	been	be	AUX
admet-801	116	17	found	find	VERB
admet-801	116	18	;	;	PUNCT
admet-801	116	19	however	however	ADV
admet-801	116	20	,	,	PUNCT
admet-801	116	21	in	in	ADP
admet-801	116	22	this	this	DET
admet-801	116	23	case	case	NOUN
admet-801	116	24	,	,	PUNCT
admet-801	116	25	a	a	DET
admet-801	116	26	dissolution	dissolution	ADJ
admet-801	116	27	medium	medium	NOUN
admet-801	116	28	with	with	ADP
admet-801	116	29	low	low	ADJ
admet-801	116	30	ph	ph	NOUN
admet-801	116	31	was	be	AUX
admet-801	116	32	an	an	DET
admet-801	116	33	important	important	ADJ
admet-801	116	34	factor	factor	NOUN
admet-801	116	35	for	for	ADP
admet-801	116	36	the	the	DET
admet-801	116	37	low	low	ADJ
admet-801	116	38	dissolution	dissolution	NOUN
admet-801	116	39	of	of	ADP
admet-801	116	40	furosemide	furosemide	NOUN
admet-801	116	41	.	.	PUNCT
admet-801	117	1	as	as	ADP
admet-801	117	2	more	more	ADJ
admet-801	117	3	than	than	ADP
admet-801	117	4	80	80	NUM
admet-801	117	5	%	%	NOUN
admet-801	117	6	of	of	ADP
admet-801	117	7	the	the	DET
admet-801	117	8	drug	drug	NOUN
admet-801	117	9	dissolved	dissolve	VERB
admet-801	117	10	at	at	ADP
admet-801	117	11	60	60	NUM
admet-801	117	12	min	min	NOUN
admet-801	117	13	at	at	ADP
admet-801	117	14	ph	ph	PROPN
admet-801	117	15	6.8	6.8	NUM
admet-801	117	16	and	and	CCONJ
admet-801	117	17	,	,	PUNCT
admet-801	117	18	for	for	ADP
admet-801	117	19	comparative	comparative	ADJ
admet-801	117	20	purposes	purpose	NOUN
admet-801	117	21	,	,	PUNCT
admet-801	117	22	the	the	DET
admet-801	117	23	dissolution	dissolution	ADJ
admet-801	117	24	profile	profile	NOUN
admet-801	117	25	of	of	ADP
admet-801	117	26	furosemide	furosemide	ADJ
admet-801	117	27	tablets	tablet	NOUN
admet-801	117	28	was	be	AUX
admet-801	117	29	obtained	obtain	VERB
admet-801	117	30	using	use	VERB
admet-801	117	31	a	a	DET
admet-801	117	32	pharmacopoeial	pharmacopoeial	ADJ
admet-801	117	33	method	method	NOUN
admet-801	117	34	.	.	PUNCT
admet-801	118	1	a	a	DET
admet-801	118	2	test	test	NOUN
admet-801	118	3	was	be	AUX
admet-801	118	4	carried	carry	VERB
admet-801	118	5	out	out	ADP
admet-801	118	6	with	with	ADP
admet-801	118	7	usp	usp	NOUN
admet-801	118	8	apparatus	apparatus	NOUN
admet-801	118	9	2	2	NUM
admet-801	118	10	at	at	ADP
admet-801	118	11	50	50	NUM
admet-801	118	12	rpm	rpm	NOUN
admet-801	118	13	with	with	ADP
admet-801	118	14	900	900	NUM
admet-801	118	15	ml	ml	NOUN
admet-801	118	16	of	of	ADP
admet-801	118	17	phosphate	phosphate	ADJ
admet-801	118	18	buffer	buffer	NOUN
admet-801	118	19	(	(	PUNCT
admet-801	118	20	ph	ph	NOUN
admet-801	118	21	5.8	5.8	NUM
admet-801	118	22	)	)	PUNCT
admet-801	118	23	(	(	PUNCT
admet-801	118	24	q	q	NOUN
admet-801	118	25	=	=	SYM
admet-801	118	26	80	80	NUM
admet-801	118	27	%	%	NOUN
admet-801	118	28	at	at	ADP
admet-801	118	29	60	60	NUM
admet-801	118	30	min	min	NOUN
admet-801	118	31	)	)	PUNCT
admet-801	118	32	,	,	PUNCT
admet-801	118	33	the	the	DET
admet-801	118	34	results	result	NOUN
admet-801	118	35	of	of	ADP
admet-801	118	36	which	which	PRON
admet-801	118	37	are	be	AUX
admet-801	118	38	shown	show	VERB
admet-801	118	39	in	in	ADP
admet-801	118	40	figure	figure	NOUN
admet-801	118	41	4	4	NUM
admet-801	118	42	.	.	PUNCT
admet-801	118	43	figure	figure	VERB
admet-801	118	44	4	4	NUM
admet-801	118	45	.	.	PUNCT
admet-801	119	1	dissolution	dissolution	ADJ
admet-801	119	2	profiles	profile	NOUN
admet-801	119	3	of	of	ADP
admet-801	119	4	furosemide	furosemide	ADJ
admet-801	119	5	reference	reference	NOUN
admet-801	119	6	tablets	tablet	NOUN
admet-801	119	7	using	use	VERB
admet-801	119	8	the	the	DET
admet-801	119	9	pharmacopoeial	pharmacopoeial	ADJ
admet-801	119	10	conditions	condition	NOUN
admet-801	119	11	(	(	PUNCT
admet-801	119	12	usp	usp	NOUN
admet-801	119	13	2	2	NUM
admet-801	119	14	)	)	PUNCT
admet-801	119	15	and	and	CCONJ
admet-801	119	16	flow	flow	NOUN
admet-801	119	17	-	-	PUNCT
admet-801	119	18	through	through	ADP
admet-801	119	19	cell	cell	NOUN
admet-801	119	20	method	method	NOUN
admet-801	119	21	(	(	PUNCT
admet-801	119	22	usp	usp	NOUN
admet-801	119	23	4	4	NUM
admet-801	119	24	)	)	PUNCT
admet-801	119	25	with	with	ADP
admet-801	119	26	different	different	ADJ
admet-801	119	27	dissolution	dissolution	NOUN
admet-801	119	28	media	medium	NOUN
admet-801	119	29	.	.	PUNCT
admet-801	120	1	mean	mean	NOUN
admet-801	120	2	±	±	NUM
admet-801	120	3	sd	sd	NOUN
admet-801	120	4	,	,	PUNCT
admet-801	120	5	n	n	NOUN
admet-801	120	6	=	=	NUM
admet-801	120	7	12	12	NUM
admet-801	120	8	.	.	PUNCT
admet-801	121	1	under	under	ADP
admet-801	121	2	official	official	ADJ
admet-801	121	3	conditions	condition	NOUN
admet-801	121	4	,	,	PUNCT
admet-801	121	5	the	the	DET
admet-801	121	6	furosemide	furosemide	ADJ
admet-801	121	7	tablets	tablet	NOUN
admet-801	121	8	met	meet	VERB
admet-801	121	9	the	the	DET
admet-801	121	10	q	q	PUNCT
admet-801	121	11	pharmacopoeial	pharmacopoeial	ADJ
admet-801	121	12	specification	specification	NOUN
admet-801	121	13	(	(	PUNCT
admet-801	121	14	>	>	SYM
admet-801	121	15	80	80	NUM
admet-801	121	16	%	%	NOUN
admet-801	121	17	dissolved	dissolve	VERB
admet-801	121	18	at	at	ADP
admet-801	121	19	60	60	NUM
admet-801	121	20	min	min	NOUN
admet-801	121	21	)	)	PUNCT
admet-801	121	22	.	.	PUNCT
admet-801	122	1	the	the	DET
admet-801	122	2	dissolution	dissolution	ADJ
admet-801	122	3	profiles	profile	NOUN
admet-801	122	4	of	of	ADP
admet-801	122	5	usp	usp	NOUN
admet-801	122	6	apparatuses	apparatus	NOUN
admet-801	122	7	2	2	NUM
admet-801	122	8	and	and	CCONJ
admet-801	122	9	4	4	NUM
admet-801	122	10	were	be	AUX
admet-801	122	11	similar	similar	ADJ
admet-801	122	12	(	(	PUNCT
admet-801	122	13	f2	f2	X
admet-801	122	14	>	>	X
admet-801	122	15	50	50	NUM
admet-801	122	16	)	)	PUNCT
admet-801	122	17	.	.	PUNCT
admet-801	123	1	this	this	DET
admet-801	123	2	result	result	NOUN
admet-801	123	3	suggested	suggest	VERB
admet-801	123	4	that	that	SCONJ
admet-801	123	5	a	a	DET
admet-801	123	6	pharmacopoeial	pharmacopoeial	ADJ
admet-801	123	7	method	method	NOUN
admet-801	123	8	(	(	PUNCT
admet-801	123	9	usp	usp	NOUN
admet-801	123	10	apparatus	apparatus	NOUN
admet-801	123	11	2	2	NUM
admet-801	123	12	)	)	PUNCT
admet-801	123	13	can	can	AUX
admet-801	123	14	produce	produce	VERB
admet-801	123	15	a	a	DET
admet-801	123	16	similar	similar	ADJ
admet-801	123	17	dissolution	dissolution	NOUN
admet-801	123	18	profile	profile	NOUN
admet-801	123	19	to	to	ADP
admet-801	123	20	that	that	PRON
admet-801	123	21	obtained	obtain	VERB
admet-801	123	22	with	with	ADP
admet-801	123	23	equipment	equipment	NOUN
admet-801	123	24	(	(	PUNCT
admet-801	123	25	usp	usp	NOUN
admet-801	123	26	apparatus	apparatus	NOUN
admet-801	123	27	4	4	NUM
admet-801	123	28	)	)	PUNCT
admet-801	123	29	that	that	PRON
admet-801	123	30	generates	generate	VERB
admet-801	123	31	a	a	DET
admet-801	123	32	hydrodynamic	hydrodynamic	ADJ
admet-801	123	33	environment	environment	NOUN
admet-801	123	34	similar	similar	ADJ
admet-801	123	35	to	to	ADP
admet-801	123	36	that	that	PRON
admet-801	123	37	inside	inside	ADP
admet-801	123	38	the	the	DET
admet-801	123	39	gastrointestinal	gastrointestinal	ADJ
admet-801	123	40	tract	tract	NOUN
admet-801	123	41	and	and	CCONJ
admet-801	123	42	for	for	ADP
admet-801	123	43	which	which	PRON
admet-801	123	44	a	a	DET
admet-801	123	45	correlation	correlation	NOUN
admet-801	123	46	with	with	ADP
admet-801	123	47	in	in	ADP
admet-801	123	48	vivo	vivo	ADJ
admet-801	123	49	data	datum	NOUN
admet-801	123	50	has	have	AUX
admet-801	123	51	been	be	AUX
admet-801	123	52	shown	show	VERB
admet-801	123	53	[	[	PUNCT
admet-801	123	54	19,20	19,20	NUM
admet-801	123	55	]	]	X
admet-801	123	56	.	.	PUNCT
admet-801	124	1	for	for	ADP
admet-801	124	2	a	a	DET
admet-801	124	3	complete	complete	ADJ
admet-801	124	4	comparison	comparison	NOUN
admet-801	124	5	between	between	ADP
admet-801	124	6	the	the	DET
admet-801	124	7	profiles	profile	NOUN
admet-801	124	8	,	,	PUNCT
admet-801	124	9	model	model	NOUN
admet-801	124	10	-	-	ADJ
admet-801	124	11	independent	independent	ADJ
admet-801	124	12	and	and	CCONJ
admet-801	124	13	-dependent	-dependent	ADJ
admet-801	124	14	parameters	parameter	NOUN
admet-801	124	15	were	be	AUX
admet-801	124	16	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	ADJ
admet-801	124	17	medina	medina	PROPN
admet-801	124	18	-	-	PUNCT
admet-801	124	19	lópez	lópez	PROPN
admet-801	124	20	et	et	PROPN
admet-801	124	21	al	al	PROPN
admet-801	124	22	.	.	PROPN
admet-801	124	23	admet	admet	PROPN
admet-801	124	24	&	&	CCONJ
admet-801	124	25	dmpk	dmpk	PROPN
admet-801	124	26	8(4	8(4	NOUN
admet-801	124	27	)	)	PUNCT
admet-801	124	28	(	(	PUNCT
admet-801	124	29	2020	2020	NUM
admet-801	124	30	)	)	PUNCT
admet-801	124	31	411	411	NUM
admet-801	124	32	-	-	SYM
admet-801	124	33	423	423	NUM
admet-801	124	34	418	418	NUM
admet-801	124	35	calculated	calculate	VERB
admet-801	124	36	and	and	CCONJ
admet-801	124	37	statistically	statistically	ADV
admet-801	124	38	compared	compare	VERB
admet-801	124	39	,	,	PUNCT
admet-801	124	40	the	the	DET
admet-801	124	41	results	result	NOUN
admet-801	124	42	of	of	ADP
admet-801	124	43	which	which	PRON
admet-801	124	44	are	be	AUX
admet-801	124	45	shown	show	VERB
admet-801	124	46	in	in	ADP
admet-801	124	47	table	table	NOUN
admet-801	124	48	4	4	NUM
admet-801	124	49	.	.	PUNCT
admet-801	124	50	table	table	NOUN
admet-801	124	51	4	4	NUM
admet-801	124	52	.	.	PUNCT
admet-801	124	53	model	model	NOUN
admet-801	124	54	-	-	PUNCT
admet-801	124	55	independent	independent	ADJ
admet-801	124	56	and	and	CCONJ
admet-801	124	57	-dependent	-dependent	ADJ
admet-801	124	58	parameters	parameter	NOUN
admet-801	124	59	of	of	ADP
admet-801	124	60	furosemide	furosemide	NOUN
admet-801	124	61	.	.	PUNCT
admet-801	125	1	mean	mean	NOUN
admet-801	125	2	±	±	NUM
admet-801	125	3	sem	sem	PROPN
admet-801	125	4	,	,	PUNCT
admet-801	125	5	n	n	NOUN
admet-801	125	6	=	=	NUM
admet-801	125	7	12	12	NUM
admet-801	125	8	.	.	PUNCT
admet-801	126	1	parameter	parameter	PROPN
admet-801	126	2	usp	usp	PROPN
admet-801	126	3	apparatus	apparatus	PROPN
admet-801	126	4	2	2	NUM
admet-801	126	5	(	(	PUNCT
admet-801	126	6	ph	ph	VERB
admet-801	126	7	5.8	5.8	NUM
admet-801	126	8	)	)	PUNCT
admet-801	126	9	usp	usp	NOUN
admet-801	126	10	apparatus	apparatus	NOUN
admet-801	126	11	4	4	NUM
admet-801	126	12	(	(	PUNCT
admet-801	126	13	ph	ph	ADJ
admet-801	126	14	6.8	6.8	NUM
admet-801	126	15	)	)	PUNCT
admet-801	126	16	diss	diss	PROPN
admet-801	126	17	.	.	PUNCT
admet-801	127	1	at	at	ADP
admet-801	127	2	60	60	NUM
admet-801	127	3	min	min	NOUN
admet-801	127	4	(	(	PUNCT
admet-801	127	5	%	%	NOUN
admet-801	127	6	)	)	PUNCT
admet-801	127	7	102.55	102.55	NUM
admet-801	127	8	±	±	NUM
admet-801	127	9	0.61	0.61	NUM
admet-801	127	10	89.49	89.49	NUM
admet-801	127	11	±	±	NOUN
admet-801	127	12	1.50	1.50	NUM
admet-801	127	13	*	*	PUNCT
admet-801	127	14	mdt	mdt	PROPN
admet-801	127	15	(	(	PUNCT
admet-801	127	16	min	min	PROPN
admet-801	127	17	)	)	PUNCT
admet-801	127	18	15.61	15.61	NUM
admet-801	127	19	±	±	NUM
admet-801	127	20	0.68	0.68	NUM
admet-801	127	21	15.28	15.28	NUM
admet-801	127	22	±	±	NUM
admet-801	127	23	1.06	1.06	NUM
admet-801	127	24	de	de	X
admet-801	127	25	(	(	PUNCT
admet-801	127	26	%	%	INTJ
admet-801	127	27	)	)	PUNCT
admet-801	127	28	75.93	75.93	NUM
admet-801	127	29	±	±	NUM
admet-801	127	30	1.52	1.52	NUM
admet-801	127	31	66.57	66.57	NUM
admet-801	127	32	±	±	NUM
admet-801	127	33	1.44	1.44	NUM
admet-801	127	34	*	*	PUNCT
admet-801	127	35	t50	t50	NUM
admet-801	127	36	%	%	NOUN
admet-801	127	37	(	(	PUNCT
admet-801	127	38	min	min	NOUN
admet-801	127	39	)	)	PUNCT
admet-801	127	40	10.86	10.86	NUM
admet-801	127	41	±	±	NUM
admet-801	127	42	0.79	0.79	NUM
admet-801	127	43	13.35	13.35	NUM
admet-801	127	44	±	±	NUM
admet-801	127	45	1.10	1.10	NUM
admet-801	127	46	t80	t80	NOUN
admet-801	127	47	%	%	NOUN
admet-801	127	48	(	(	PUNCT
admet-801	127	49	min	min	NOUN
admet-801	127	50	)	)	PUNCT
admet-801	127	51	25.99	25.99	NUM
admet-801	127	52	±	±	NUM
admet-801	127	53	1.50	1.50	NUM
admet-801	127	54	36.64	36.64	NUM
admet-801	127	55	±	±	NUM
admet-801	127	56	2.34	2.34	NUM
admet-801	127	57	*	*	PUNCT
admet-801	127	58	*	*	PUNCT
admet-801	127	59	p	p	X
admet-801	127	60	<	<	X
admet-801	127	61	0.05	0.05	NUM
admet-801	127	62	.	.	PUNCT
admet-801	128	1	significant	significant	ADJ
admet-801	128	2	differences	difference	NOUN
admet-801	128	3	were	be	AUX
admet-801	128	4	observed	observe	VERB
admet-801	128	5	in	in	ADP
admet-801	128	6	percent	percent	NOUN
admet-801	128	7	dissolved	dissolve	VERB
admet-801	128	8	at	at	ADP
admet-801	128	9	60	60	NUM
admet-801	128	10	min	min	NOUN
admet-801	128	11	,	,	PUNCT
admet-801	128	12	de	de	X
admet-801	128	13	,	,	PUNCT
admet-801	128	14	and	and	CCONJ
admet-801	128	15	t80	t80	PROPN
admet-801	128	16	%	%	NOUN
admet-801	128	17	values	value	NOUN
admet-801	128	18	(	(	PUNCT
admet-801	128	19	p	p	X
admet-801	128	20	<	<	X
admet-801	128	21	0.05	0.05	NUM
admet-801	128	22	)	)	PUNCT
admet-801	128	23	,	,	PUNCT
admet-801	128	24	whereas	whereas	SCONJ
admet-801	128	25	there	there	PRON
admet-801	128	26	was	be	VERB
admet-801	128	27	no	no	DET
admet-801	128	28	difference	difference	NOUN
admet-801	128	29	in	in	ADP
admet-801	128	30	mdt	mdt	PROPN
admet-801	128	31	and	and	CCONJ
admet-801	128	32	t50	t50	NOUN
admet-801	128	33	%	%	NOUN
admet-801	128	34	,	,	PUNCT
admet-801	128	35	between	between	ADP
admet-801	128	36	usp	usp	NOUN
admet-801	128	37	apparatuses	apparatuse	VERB
admet-801	128	38	2	2	NUM
admet-801	128	39	and	and	CCONJ
admet-801	128	40	4	4	NUM
admet-801	128	41	.	.	PUNCT
admet-801	129	1	if	if	SCONJ
admet-801	129	2	we	we	PRON
admet-801	129	3	consider	consider	VERB
admet-801	129	4	mdt	mdt	NOUN
admet-801	129	5	and	and	CCONJ
admet-801	129	6	t50	t50	NOUN
admet-801	129	7	%	%	NOUN
admet-801	129	8	as	as	ADP
admet-801	129	9	parameters	parameter	NOUN
admet-801	129	10	that	that	PRON
admet-801	129	11	reflect	reflect	VERB
admet-801	129	12	the	the	DET
admet-801	129	13	in	in	ADV
admet-801	129	14	vitro	vitro	X
admet-801	129	15	dissolution	dissolution	NOUN
admet-801	129	16	rate	rate	NOUN
admet-801	129	17	,	,	PUNCT
admet-801	129	18	this	this	PRON
admet-801	129	19	is	be	AUX
admet-801	129	20	similar	similar	ADJ
admet-801	129	21	between	between	ADP
admet-801	129	22	the	the	DET
admet-801	129	23	conditions	condition	NOUN
admet-801	129	24	(	(	PUNCT
admet-801	129	25	usp	usp	NOUN
admet-801	129	26	apparatus	apparatus	NOUN
admet-801	129	27	2	2	NUM
admet-801	129	28	at	at	ADP
admet-801	129	29	50	50	NUM
admet-801	129	30	rpm	rpm	ADJ
admet-801	129	31	and	and	CCONJ
admet-801	129	32	phosphate	phosphate	ADJ
admet-801	129	33	buffer	buffer	NOUN
admet-801	129	34	(	(	PUNCT
admet-801	129	35	ph	ph	NOUN
admet-801	129	36	5.8)/usp	5.8)/usp	NUM
admet-801	129	37	apparatus	apparatus	NOUN
admet-801	129	38	4	4	NUM
admet-801	129	39	with	with	ADP
admet-801	129	40	a	a	DET
admet-801	129	41	laminar	laminar	ADJ
admet-801	129	42	flow	flow	NOUN
admet-801	129	43	of	of	ADP
admet-801	129	44	16	16	NUM
admet-801	129	45	ml	ml	NOUN
admet-801	129	46	/	/	SYM
admet-801	129	47	min	min	NOUN
admet-801	129	48	and	and	CCONJ
admet-801	129	49	phosphate	phosphate	ADJ
admet-801	129	50	buffer	buffer	NOUN
admet-801	129	51	(	(	PUNCT
admet-801	129	52	ph	ph	NOUN
admet-801	129	53	6.8	6.8	NUM
admet-801	129	54	)	)	PUNCT
admet-801	129	55	)	)	PUNCT
admet-801	129	56	,	,	PUNCT
admet-801	129	57	at	at	ADP
admet-801	129	58	least	least	ADJ
admet-801	129	59	until	until	ADP
admet-801	129	60	the	the	DET
admet-801	129	61	time	time	NOUN
admet-801	129	62	at	at	ADP
admet-801	129	63	which	which	PRON
admet-801	129	64	63.2	63.2	NUM
admet-801	129	65	%	%	NOUN
admet-801	129	66	of	of	ADP
admet-801	129	67	the	the	DET
admet-801	129	68	drug	drug	NOUN
admet-801	129	69	is	be	AUX
admet-801	129	70	dissolved	dissolve	VERB
admet-801	129	71	.	.	PUNCT
admet-801	130	1	furosemide	furosemide	PROPN
admet-801	130	2	dissolution	dissolution	PROPN
admet-801	130	3	data	datum	NOUN
admet-801	130	4	obtained	obtain	VERB
admet-801	130	5	with	with	ADP
admet-801	130	6	pharmacopoeial	pharmacopoeial	ADJ
admet-801	130	7	conditions	condition	NOUN
admet-801	130	8	and	and	CCONJ
admet-801	130	9	the	the	DET
admet-801	130	10	flow	flow	NOUN
admet-801	130	11	-	-	PUNCT
admet-801	130	12	through	through	ADP
admet-801	130	13	cell	cell	NOUN
admet-801	130	14	method	method	NOUN
admet-801	130	15	,	,	PUNCT
admet-801	130	16	adjusted	adjust	VERB
admet-801	130	17	to	to	ADP
admet-801	130	18	mathematical	mathematical	ADJ
admet-801	130	19	models	model	NOUN
admet-801	130	20	,	,	PUNCT
admet-801	130	21	are	be	AUX
admet-801	130	22	shown	show	VERB
admet-801	130	23	in	in	ADP
admet-801	130	24	table	table	NOUN
admet-801	130	25	5	5	NUM
admet-801	130	26	.	.	PUNCT
admet-801	130	27	table	table	NOUN
admet-801	130	28	5	5	NUM
admet-801	130	29	.	.	PUNCT
admet-801	130	30	criteria	criterion	NOUN
admet-801	130	31	used	use	VERB
admet-801	130	32	for	for	ADP
admet-801	130	33	the	the	DET
admet-801	130	34	selection	selection	NOUN
admet-801	130	35	of	of	ADP
admet-801	130	36	the	the	DET
admet-801	130	37	best	good	ADJ
admet-801	130	38	-	-	PUNCT
admet-801	130	39	fit	fit	NOUN
admet-801	130	40	model	model	NOUN
admet-801	130	41	.	.	PUNCT
admet-801	131	1	mean	mean	VERB
admet-801	131	2	,	,	PUNCT
admet-801	131	3	n	n	NOUN
admet-801	131	4	=	=	NUM
admet-801	131	5	12	12	NUM
admet-801	131	6	.	.	PUNCT
admet-801	132	1	parameter	parameter	PROPN
admet-801	132	2	usp	usp	PROPN
admet-801	132	3	apparatus	apparatus	PROPN
admet-801	132	4	zero	zero	NUM
admet-801	132	5	-	-	PUNCT
admet-801	132	6	order	order	NOUN
admet-801	132	7	first	first	ADJ
admet-801	132	8	-	-	PUNCT
admet-801	132	9	order	order	NOUN
admet-801	132	10	higuchi	higuchi	PROPN
admet-801	132	11	hixsoncrowell	hixsoncrowell	PROPN
admet-801	132	12	makoidbanakar	makoidbanakar	PROPN
admet-801	133	1	weibull	weibull	PROPN
admet-801	133	2	r	r	PROPN
admet-801	133	3	2	2	NUM
admet-801	133	4	adjusted	adjust	VERB
admet-801	133	5	2	2	NUM
admet-801	133	6	(	(	PUNCT
admet-801	133	7	ph	ph	NOUN
admet-801	133	8	5.8	5.8	NUM
admet-801	133	9	)	)	PUNCT
admet-801	133	10	0.1571	0.1571	NUM
admet-801	134	1	0.9788	0.9788	NUM
admet-801	134	2	0.9152	0.9152	NUM
admet-801	134	3	0.9882	0.9882	NUM
admet-801	134	4	0.9770	0.9770	NUM
admet-801	134	5	0.9994	0.9994	NUM
admet-801	134	6	4	4	NUM
admet-801	134	7	(	(	PUNCT
admet-801	134	8	ph	ph	NOUN
admet-801	134	9	6.8	6.8	NUM
admet-801	134	10	)	)	PUNCT
admet-801	134	11	0.0115	0.0115	NUM
admet-801	134	12	0.9205	0.9205	NUM
admet-801	134	13	0.8048	0.8048	NUM
admet-801	134	14	0.8488	0.8488	NUM
admet-801	134	15	0.9743	0.9743	NUM
admet-801	134	16	0.9991	0.9991	NUM
admet-801	134	17	aic	aic	PROPN
admet-801	134	18	2	2	NUM
admet-801	134	19	(	(	PUNCT
admet-801	134	20	ph	ph	NOUN
admet-801	134	21	5.8	5.8	NUM
admet-801	134	22	)	)	PUNCT
admet-801	134	23	104.08	104.08	NUM
admet-801	134	24	58.28	58.28	NUM
admet-801	134	25	75.30	75.30	NUM
admet-801	134	26	52.62	52.62	NUM
admet-801	134	27	30.04	30.04	NUM
admet-801	134	28	8.29	8.29	NUM
admet-801	134	29	4	4	NUM
admet-801	134	30	(	(	PUNCT
admet-801	134	31	ph	ph	NOUN
admet-801	134	32	6.8	6.8	NUM
admet-801	134	33	)	)	PUNCT
admet-801	134	34	101.87	101.87	NUM
admet-801	134	35	66.11	66.11	NUM
admet-801	134	36	81.14	81.14	NUM
admet-801	134	37	74.67	74.67	NUM
admet-801	134	38	57.47	57.47	NUM
admet-801	134	39	15.79	15.79	NUM
admet-801	134	40	the	the	DET
admet-801	134	41	weibull	weibull	PROPN
admet-801	134	42	function	function	NOUN
admet-801	134	43	was	be	AUX
admet-801	134	44	the	the	DET
admet-801	134	45	best	good	ADJ
admet-801	134	46	-	-	PUNCT
admet-801	134	47	fit	fit	ADJ
admet-801	134	48	model	model	NOUN
admet-801	134	49	to	to	PART
admet-801	134	50	describe	describe	VERB
admet-801	134	51	the	the	DET
admet-801	134	52	in	in	ADV
admet-801	134	53	vitro	vitro	X
admet-801	134	54	release	release	NOUN
admet-801	134	55	performance	performance	NOUN
admet-801	134	56	of	of	ADP
admet-801	134	57	furosemide	furosemide	ADJ
admet-801	134	58	reference	reference	NOUN
admet-801	134	59	tablets	tablet	NOUN
admet-801	134	60	in	in	ADP
admet-801	134	61	these	these	DET
admet-801	134	62	two	two	NUM
admet-801	134	63	dissolution	dissolution	ADJ
admet-801	134	64	apparatuses	apparatus	NOUN
admet-801	134	65	.	.	PUNCT
admet-801	135	1	weibull	weibull	PROPN
admet-801	135	2	parameters	parameter	NOUN
admet-801	135	3	and	and	CCONJ
admet-801	135	4	td	td	NOUN
admet-801	135	5	values	value	NOUN
admet-801	135	6	are	be	AUX
admet-801	135	7	shown	show	VERB
admet-801	135	8	in	in	ADP
admet-801	135	9	table	table	NOUN
admet-801	135	10	6	6	NUM
admet-801	135	11	.	.	PUNCT
admet-801	136	1	no	no	DET
admet-801	136	2	significant	significant	ADJ
admet-801	136	3	differences	difference	NOUN
admet-801	136	4	were	be	AUX
admet-801	136	5	observed	observe	VERB
admet-801	136	6	in	in	ADP
admet-801	136	7	the	the	DET
admet-801	136	8	td	td	NOUN
admet-801	136	9	data	datum	NOUN
admet-801	136	10	between	between	ADP
admet-801	136	11	the	the	DET
admet-801	136	12	apparatuses	apparatus	NOUN
admet-801	136	13	(	(	PUNCT
admet-801	136	14	p	p	X
admet-801	136	15	>	>	X
admet-801	136	16	0.05	0.05	NUM
admet-801	136	17	)	)	PUNCT
admet-801	136	18	.	.	PUNCT
admet-801	137	1	table	table	NOUN
admet-801	137	2	6	6	NUM
admet-801	137	3	.	.	PUNCT
admet-801	138	1	weibull	weibull	PROPN
admet-801	138	2	parameters	parameter	NOUN
admet-801	138	3	and	and	CCONJ
admet-801	138	4	td	td	NOUN
admet-801	138	5	values	value	NOUN
admet-801	138	6	.	.	PUNCT
admet-801	139	1	mean	mean	VERB
admet-801	139	2	,	,	PUNCT
admet-801	139	3	n	n	NOUN
admet-801	139	4	=	=	NUM
admet-801	139	5	12	12	NUM
admet-801	139	6	.	.	PUNCT
admet-801	139	7	usp	usp	NOUN
admet-801	139	8	apparatus	apparatus	NOUN
admet-801	139	9	α	α	PROPN
admet-801	139	10	β	β	X
admet-801	139	11	ti	ti	X
admet-801	139	12	fmax	fmax	PROPN
admet-801	139	13	td	td	PROPN
admet-801	139	14	±	±	NUM
admet-801	139	15	sem	sem	NOUN
admet-801	139	16	(	(	PUNCT
admet-801	139	17	min	min	NOUN
admet-801	139	18	)	)	PUNCT
admet-801	139	19	2	2	NUM
admet-801	139	20	(	(	PUNCT
admet-801	139	21	ph	ph	NOUN
admet-801	139	22	5.8	5.8	NUM
admet-801	139	23	)	)	PUNCT
admet-801	139	24	626.71	626.71	NUM
admet-801	139	25	1.13	1.13	NUM
admet-801	139	26	-1.99	-1.99	NUM
admet-801	139	27	110.39	110.39	NUM
admet-801	139	28	20.89	20.89	NUM
admet-801	139	29	±	±	NUM
admet-801	139	30	3.93	3.93	NUM
admet-801	139	31	4	4	NUM
admet-801	139	32	(	(	PUNCT
admet-801	139	33	ph	ph	NOUN
admet-801	139	34	6.8	6.8	NUM
admet-801	139	35	)	)	PUNCT
admet-801	139	36	12.22	12.22	NUM
admet-801	139	37	0.89	0.89	NUM
admet-801	139	38	3.12	3.12	NUM
admet-801	139	39	92.57	92.57	NUM
admet-801	139	40	16.63	16.63	NUM
admet-801	139	41	±	±	NUM
admet-801	139	42	1.43	1.43	NUM
admet-801	139	43	*	*	PUNCT
admet-801	139	44	p	p	X
admet-801	139	45	<	<	X
admet-801	139	46	0.05	0.05	NUM
admet-801	139	47	the	the	DET
admet-801	139	48	dissolution	dissolution	NOUN
admet-801	139	49	of	of	ADP
admet-801	139	50	furosemide	furosemide	ADJ
admet-801	139	51	reference	reference	NOUN
admet-801	139	52	tablets	tablet	NOUN
admet-801	139	53	using	use	VERB
admet-801	139	54	usp	usp	NOUN
admet-801	139	55	apparatus	apparatus	NOUN
admet-801	139	56	4	4	NUM
admet-801	139	57	exceeded	exceed	VERB
admet-801	139	58	the	the	DET
admet-801	139	59	q	q	PUNCT
admet-801	139	60	pharmacopoeial	pharmacopoeial	ADJ
admet-801	139	61	criterion	criterion	NOUN
admet-801	139	62	(	(	PUNCT
admet-801	139	63	only	only	ADV
admet-801	139	64	at	at	ADP
admet-801	139	65	ph	ph	PROPN
admet-801	139	66	6.8	6.8	NUM
admet-801	139	67	)	)	PUNCT
admet-801	139	68	set	set	VERB
admet-801	139	69	for	for	ADP
admet-801	139	70	certain	certain	ADJ
admet-801	139	71	conditions	condition	NOUN
admet-801	139	72	in	in	ADP
admet-801	139	73	the	the	DET
admet-801	139	74	usp	usp	NOUN
admet-801	139	75	apparatus	apparatus	NOUN
admet-801	139	76	2	2	NUM
admet-801	139	77	.	.	PUNCT
admet-801	139	78	when	when	SCONJ
admet-801	139	79	the	the	DET
admet-801	139	80	dissolution	dissolution	NOUN
admet-801	139	81	data	datum	NOUN
admet-801	139	82	of	of	ADP
admet-801	139	83	usp	usp	PROPN
admet-801	139	84	apparatus	apparatus	NOUN
admet-801	139	85	4	4	NUM
admet-801	139	86	were	be	AUX
admet-801	139	87	compared	compare	VERB
admet-801	139	88	with	with	ADP
admet-801	139	89	those	those	PRON
admet-801	139	90	of	of	ADP
admet-801	139	91	usp	usp	NOUN
admet-801	139	92	apparatus	apparatus	NOUN
admet-801	139	93	2	2	NUM
admet-801	139	94	(	(	PUNCT
admet-801	139	95	50	50	NUM
admet-801	139	96	rpm	rpm	ADJ
admet-801	139	97	and	and	CCONJ
admet-801	139	98	phosphate	phosphate	ADJ
admet-801	139	99	buffer	buffer	NOUN
admet-801	139	100	ph	ph	VERB
admet-801	139	101	5.8	5.8	NUM
admet-801	139	102	)	)	PUNCT
admet-801	139	103	,	,	PUNCT
admet-801	139	104	an	an	DET
admet-801	139	105	equivalent	equivalent	NOUN
admet-801	139	106	in	in	ADP
admet-801	139	107	vitro	vitro	X
admet-801	139	108	release	release	NOUN
admet-801	139	109	performance	performance	NOUN
admet-801	139	110	was	be	AUX
admet-801	139	111	achieved	achieve	VERB
admet-801	139	112	based	base	VERB
admet-801	139	113	on	on	ADP
admet-801	139	114	f2	f2	PROPN
admet-801	139	115	,	,	PUNCT
admet-801	139	116	mdt	mdt	PROPN
admet-801	139	117	,	,	PUNCT
admet-801	139	118	t50	t50	NOUN
admet-801	139	119	%	%	NOUN
admet-801	139	120	,	,	PUNCT
admet-801	139	121	and	and	CCONJ
admet-801	139	122	td	td	NOUN
admet-801	139	123	comparisons	comparison	NOUN
admet-801	139	124	.	.	PUNCT
admet-801	140	1	under	under	ADP
admet-801	140	2	all	all	DET
admet-801	140	3	conditions	condition	NOUN
admet-801	140	4	used	use	VERB
admet-801	140	5	,	,	PUNCT
admet-801	140	6	furosemide	furosemide	VERB
admet-801	140	7	dissolution	dissolution	ADJ
admet-801	140	8	profiles	profile	NOUN
admet-801	140	9	were	be	AUX
admet-801	140	10	well	well	ADV
admet-801	140	11	described	describe	VERB
admet-801	140	12	by	by	ADP
admet-801	140	13	weibull	weibull	PROPN
admet-801	140	14	function	function	PROPN
admet-801	140	15	.	.	PUNCT
admet-801	141	1	the	the	DET
admet-801	141	2	shape	shape	NOUN
admet-801	141	3	factor	factor	NOUN
admet-801	141	4	of	of	ADP
admet-801	141	5	the	the	DET
admet-801	141	6	weibull	weibull	PROPN
admet-801	141	7	function	function	NOUN
admet-801	141	8	characterises	characterise	VERB
admet-801	141	9	the	the	DET
admet-801	141	10	dissolution	dissolution	NOUN
admet-801	141	11	profile	profile	NOUN
admet-801	141	12	as	as	ADP
admet-801	141	13	exponential	exponential	NOUN
admet-801	141	14	(	(	PUNCT
admet-801	141	15	β	β	X
admet-801	141	16	=	=	SYM
admet-801	141	17	1	1	NUM
admet-801	141	18	)	)	PUNCT
admet-801	141	19	;	;	PUNCT
admet-801	141	20	sigmoidal	sigmoidal	NOUN
admet-801	141	21	,	,	PUNCT
admet-801	141	22	with	with	ADP
admet-801	141	23	upward	upward	ADJ
admet-801	141	24	curvature	curvature	NOUN
admet-801	141	25	followed	follow	VERB
admet-801	141	26	by	by	ADP
admet-801	141	27	a	a	DET
admet-801	141	28	turning	turning	NOUN
admet-801	141	29	point	point	NOUN
admet-801	141	30	(	(	PUNCT
admet-801	141	31	β	β	X
admet-801	141	32	>	>	X
admet-801	141	33	1	1	NUM
admet-801	141	34	)	)	PUNCT
admet-801	141	35	;	;	PUNCT
admet-801	141	36	or	or	CCONJ
admet-801	141	37	parabolic	parabolic	NOUN
admet-801	141	38	,	,	PUNCT
admet-801	141	39	with	with	ADP
admet-801	141	40	steeper	steep	ADJ
admet-801	141	41	initial	initial	ADJ
admet-801	141	42	slope	slope	NOUN
admet-801	141	43	consistent	consistent	ADJ
admet-801	141	44	with	with	ADP
admet-801	141	45	exponential	exponential	NOUN
admet-801	141	46	(	(	PUNCT
admet-801	141	47	β	β	X
admet-801	141	48	<	<	X
admet-801	141	49	1	1	NUM
admet-801	141	50	)	)	PUNCT
admet-801	141	51	[	[	X
admet-801	141	52	28	28	NUM
admet-801	141	53	]	]	PUNCT
admet-801	141	54	.	.	PUNCT
admet-801	142	1	in	in	ADP
admet-801	142	2	this	this	DET
admet-801	142	3	case	case	NOUN
admet-801	142	4	,	,	PUNCT
admet-801	142	5	furosemide	furosemide	ADJ
admet-801	142	6	tablets	tablet	NOUN
admet-801	142	7	evaluated	evaluate	VERB
admet-801	142	8	with	with	ADP
admet-801	142	9	usp	usp	NOUN
admet-801	142	10	apparatus	apparatus	NOUN
admet-801	142	11	1	1	NUM
admet-801	142	12	at	at	ADP
admet-801	142	13	75	75	NUM
admet-801	142	14	rpm	rpm	NOUN
admet-801	142	15	and	and	CCONJ
admet-801	142	16	ph	ph	ADJ
admet-801	142	17	6.8	6.8	NUM
admet-801	142	18	,	,	PUNCT
admet-801	142	19	as	as	ADV
admet-801	142	20	well	well	ADV
admet-801	142	21	as	as	ADP
admet-801	142	22	with	with	ADP
admet-801	142	23	usp	usp	NOUN
admet-801	142	24	apparatus	apparatus	NOUN
admet-801	142	25	2	2	NUM
admet-801	142	26	at	at	ADP
admet-801	142	27	50	50	NUM
admet-801	142	28	rpm	rpm	NOUN
admet-801	142	29	and	and	CCONJ
admet-801	142	30	ph	ph	ADJ
admet-801	142	31	5.8	5.8	NUM
admet-801	142	32	,	,	PUNCT
admet-801	142	33	generated	generate	VERB
admet-801	142	34	β	β	PROPN
admet-801	142	35	values	value	NOUN
admet-801	142	36	>	>	X
admet-801	142	37	1	1	NUM
admet-801	142	38	,	,	PUNCT
admet-801	142	39	meaning	mean	VERB
admet-801	142	40	sigmoidal	sigmoidal	NOUN
admet-801	142	41	profiles	profile	NOUN
admet-801	142	42	.	.	PUNCT
admet-801	143	1	admet	admet	PROPN
admet-801	143	2	&	&	CCONJ
admet-801	143	3	dmpk	dmpk	PROPN
admet-801	143	4	8(4	8(4	NOUN
admet-801	143	5	)	)	PUNCT
admet-801	143	6	(	(	PUNCT
admet-801	143	7	2020	2020	NUM
admet-801	143	8	)	)	PUNCT
admet-801	143	9	411	411	NUM
admet-801	143	10	-	-	SYM
admet-801	143	11	423	423	NUM
admet-801	143	12	in	in	ADP
admet-801	143	13	vitro	vitro	X
admet-801	143	14	release	release	NOUN
admet-801	143	15	studies	study	NOUN
admet-801	143	16	of	of	ADP
admet-801	143	17	furosemide	furosemide	ADJ
admet-801	143	18	doi	doi	PROPN
admet-801	143	19	:	:	PUNCT
admet-801	143	20	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	VERB
admet-801	143	21	419	419	NUM
admet-801	143	22	discussion	discussion	NOUN
admet-801	143	23	several	several	ADJ
admet-801	143	24	authors	author	NOUN
admet-801	143	25	have	have	AUX
admet-801	143	26	studied	study	VERB
admet-801	143	27	the	the	DET
admet-801	143	28	effect	effect	NOUN
admet-801	143	29	of	of	ADP
admet-801	143	30	the	the	DET
admet-801	143	31	hydrodynamic	hydrodynamic	ADJ
admet-801	143	32	environment	environment	NOUN
admet-801	143	33	on	on	ADP
admet-801	143	34	the	the	DET
admet-801	143	35	tablet	tablet	NOUN
admet-801	143	36	dissolution	dissolution	NOUN
admet-801	143	37	rate	rate	NOUN
admet-801	143	38	.	.	PUNCT
admet-801	144	1	wu	wu	PROPN
admet-801	144	2	et	et	PROPN
admet-801	144	3	al	al	PROPN
admet-801	144	4	.	.	PUNCT
admet-801	145	1	[	[	X
admet-801	145	2	29	29	NUM
admet-801	145	3	]	]	PUNCT
admet-801	145	4	studied	study	VERB
admet-801	145	5	the	the	DET
admet-801	145	6	rate	rate	NOUN
admet-801	145	7	process	process	NOUN
admet-801	145	8	that	that	PRON
admet-801	145	9	underlies	underlie	VERB
admet-801	145	10	tablet	tablet	NOUN
admet-801	145	11	dissolution	dissolution	NOUN
admet-801	145	12	to	to	PART
admet-801	145	13	understand	understand	VERB
admet-801	145	14	the	the	DET
admet-801	145	15	role	role	NOUN
admet-801	145	16	of	of	ADP
admet-801	145	17	external	external	ADJ
admet-801	145	18	hydrodynamics	hydrodynamic	NOUN
admet-801	145	19	on	on	ADP
admet-801	145	20	mass	mass	ADJ
admet-801	145	21	transfer	transfer	NOUN
admet-801	145	22	rate	rate	NOUN
admet-801	145	23	and	and	CCONJ
admet-801	145	24	film	film	NOUN
admet-801	145	25	thickness	thickness	NOUN
admet-801	145	26	during	during	ADP
admet-801	145	27	dissolution	dissolution	NOUN
admet-801	145	28	.	.	PUNCT
admet-801	146	1	shah	shah	PROPN
admet-801	146	2	et	et	PROPN
admet-801	146	3	al	al	PROPN
admet-801	146	4	.	.	PUNCT
admet-801	147	1	[	[	X
admet-801	147	2	30	30	NUM
admet-801	147	3	]	]	PUNCT
admet-801	147	4	stated	state	VERB
admet-801	147	5	that	that	SCONJ
admet-801	147	6	the	the	DET
admet-801	147	7	proper	proper	ADJ
admet-801	147	8	medium	medium	ADJ
admet-801	147	9	and	and	CCONJ
admet-801	147	10	appropriate	appropriate	ADJ
admet-801	147	11	rotational	rotational	ADJ
admet-801	147	12	speed	speed	NOUN
admet-801	147	13	of	of	ADP
admet-801	147	14	the	the	DET
admet-801	147	15	basket	basket	NOUN
admet-801	147	16	and	and	CCONJ
admet-801	147	17	paddle	paddle	NOUN
admet-801	147	18	are	be	AUX
admet-801	147	19	of	of	ADP
admet-801	147	20	great	great	ADJ
admet-801	147	21	importance	importance	NOUN
admet-801	147	22	to	to	PART
admet-801	147	23	assure	assure	VERB
admet-801	147	24	that	that	SCONJ
admet-801	147	25	the	the	DET
admet-801	147	26	test	test	NOUN
admet-801	147	27	procedure	procedure	NOUN
admet-801	147	28	used	use	VERB
admet-801	147	29	is	be	AUX
admet-801	147	30	useful	useful	ADJ
admet-801	147	31	and	and	CCONJ
admet-801	147	32	discriminatory	discriminatory	ADJ
admet-801	147	33	.	.	PUNCT
admet-801	148	1	additionally	additionally	ADV
admet-801	148	2	,	,	PUNCT
admet-801	148	3	levy	levy	NOUN
admet-801	148	4	et	et	PROPN
admet-801	148	5	al	al	PROPN
admet-801	148	6	.	.	PUNCT
admet-801	149	1	[	[	X
admet-801	149	2	31	31	NUM
admet-801	149	3	]	]	PUNCT
admet-801	149	4	concluded	conclude	VERB
admet-801	149	5	that	that	SCONJ
admet-801	149	6	the	the	DET
admet-801	149	7	in	in	ADV
admet-801	149	8	vitro	vitro	X
admet-801	149	9	dissolution	dissolution	NOUN
admet-801	149	10	rate	rate	NOUN
admet-801	149	11	correlates	correlate	VERB
admet-801	149	12	with	with	ADP
admet-801	149	13	the	the	DET
admet-801	149	14	in	in	ADP
admet-801	149	15	vivo	vivo	ADJ
admet-801	149	16	absorption	absorption	NOUN
admet-801	149	17	rate	rate	NOUN
admet-801	149	18	only	only	ADV
admet-801	149	19	at	at	ADP
admet-801	149	20	a	a	DET
admet-801	149	21	low	low	ADJ
admet-801	149	22	agitation	agitation	NOUN
admet-801	149	23	rate	rate	NOUN
admet-801	149	24	(	(	PUNCT
admet-801	149	25	55	55	NUM
admet-801	149	26	rpm	rpm	NOUN
admet-801	149	27	)	)	PUNCT
admet-801	149	28	.	.	PUNCT
admet-801	150	1	these	these	DET
admet-801	150	2	results	result	NOUN
admet-801	150	3	support	support	VERB
admet-801	150	4	the	the	DET
admet-801	150	5	search	search	NOUN
admet-801	150	6	for	for	ADP
admet-801	150	7	better	well	ADJ
admet-801	150	8	dissolution	dissolution	ADJ
admet-801	150	9	schemes	scheme	NOUN
admet-801	150	10	,	,	PUNCT
admet-801	150	11	especially	especially	ADV
admet-801	150	12	with	with	ADP
admet-801	150	13	drugs	drug	NOUN
admet-801	150	14	with	with	ADP
admet-801	150	15	poor	poor	ADJ
admet-801	150	16	solubility	solubility	NOUN
admet-801	150	17	.	.	PUNCT
admet-801	151	1	poor	poor	ADJ
admet-801	151	2	permeability	permeability	NOUN
admet-801	151	3	is	be	AUX
admet-801	151	4	a	a	DET
admet-801	151	5	problem	problem	NOUN
admet-801	151	6	in	in	ADP
admet-801	151	7	the	the	DET
admet-801	151	8	design	design	NOUN
admet-801	151	9	of	of	ADP
admet-801	151	10	solid	solid	ADJ
admet-801	151	11	oral	oral	ADJ
admet-801	151	12	dosage	dosage	NOUN
admet-801	151	13	forms	form	NOUN
admet-801	151	14	with	with	ADP
admet-801	151	15	good	good	ADJ
admet-801	151	16	bioavailability	bioavailability	NOUN
admet-801	151	17	;	;	PUNCT
admet-801	151	18	thus	thus	ADV
admet-801	151	19	,	,	PUNCT
admet-801	151	20	it	it	PRON
admet-801	151	21	is	be	AUX
admet-801	151	22	important	important	ADJ
admet-801	151	23	to	to	PART
admet-801	151	24	understand	understand	VERB
admet-801	151	25	the	the	DET
admet-801	151	26	influence	influence	NOUN
admet-801	151	27	of	of	ADP
admet-801	151	28	agitation	agitation	NOUN
admet-801	151	29	rate	rate	NOUN
admet-801	151	30	,	,	PUNCT
admet-801	151	31	usp	usp	NOUN
admet-801	151	32	apparatus	apparatus	NOUN
admet-801	151	33	,	,	PUNCT
admet-801	151	34	and	and	CCONJ
admet-801	151	35	dissolution	dissolution	ADJ
admet-801	151	36	media	medium	NOUN
admet-801	151	37	on	on	ADP
admet-801	151	38	the	the	DET
admet-801	151	39	in	in	ADV
admet-801	151	40	vitro	vitro	X
admet-801	151	41	release	release	NOUN
admet-801	151	42	performance	performance	NOUN
admet-801	151	43	of	of	ADP
admet-801	151	44	class	class	NOUN
admet-801	151	45	iv	iv	NUM
admet-801	151	46	drugs	drug	NOUN
admet-801	151	47	.	.	PUNCT
admet-801	152	1	the	the	DET
admet-801	152	2	search	search	NOUN
admet-801	152	3	for	for	ADP
admet-801	152	4	adequate	adequate	ADJ
admet-801	152	5	dissolution	dissolution	ADJ
admet-801	152	6	conditions	condition	NOUN
admet-801	152	7	is	be	AUX
admet-801	152	8	not	not	PART
admet-801	152	9	limited	limit	VERB
admet-801	152	10	to	to	ADP
admet-801	152	11	poorly	poorly	ADV
admet-801	152	12	soluble	soluble	ADJ
admet-801	152	13	drugs	drug	NOUN
admet-801	152	14	or	or	CCONJ
admet-801	152	15	the	the	DET
admet-801	152	16	use	use	NOUN
admet-801	152	17	of	of	ADP
admet-801	152	18	usp	usp	NOUN
admet-801	152	19	apparatuses	apparatus	NOUN
admet-801	152	20	1	1	NUM
admet-801	152	21	and	and	CCONJ
admet-801	152	22	2	2	NUM
admet-801	152	23	.	.	X
admet-801	153	1	shabir	shabir	PROPN
admet-801	153	2	[	[	X
admet-801	153	3	32	32	NUM
admet-801	153	4	]	]	PUNCT
admet-801	153	5	indicated	indicate	VERB
admet-801	153	6	that	that	SCONJ
admet-801	153	7	the	the	DET
admet-801	153	8	rate	rate	NOUN
admet-801	153	9	of	of	ADP
admet-801	153	10	in	in	ADP
admet-801	153	11	vitro	vitro	X
admet-801	153	12	release	release	NOUN
admet-801	153	13	of	of	ADP
admet-801	153	14	a	a	DET
admet-801	153	15	hydrosoluble	hydrosoluble	ADJ
admet-801	153	16	drug	drug	NOUN
admet-801	153	17	can	can	AUX
admet-801	153	18	be	be	AUX
admet-801	153	19	accurately	accurately	ADV
admet-801	153	20	controlled	control	VERB
admet-801	153	21	through	through	ADP
admet-801	153	22	the	the	DET
admet-801	153	23	usp	usp	PROPN
admet-801	153	24	apparatus	apparatus	NOUN
admet-801	153	25	.	.	PUNCT
admet-801	154	1	shabir	shabir	PROPN
admet-801	154	2	worked	work	VERB
admet-801	154	3	with	with	ADP
admet-801	154	4	atenolol	atenolol	PROPN
admet-801	154	5	(	(	PUNCT
admet-801	154	6	class	class	NOUN
admet-801	154	7	iii	iii	NUM
admet-801	154	8	drug	drug	NOUN
admet-801	154	9	)	)	PUNCT
admet-801	154	10	generic	generic	ADJ
admet-801	154	11	tablets	tablet	NOUN
admet-801	154	12	using	use	VERB
admet-801	154	13	usp	usp	NOUN
admet-801	154	14	basket	basket	NOUN
admet-801	154	15	and	and	CCONJ
admet-801	154	16	paddle	paddle	NOUN
admet-801	154	17	apparatuses	apparatus	NOUN
admet-801	154	18	.	.	PUNCT
admet-801	155	1	although	although	SCONJ
admet-801	155	2	these	these	DET
admet-801	155	3	dissolution	dissolution	NOUN
admet-801	155	4	apparatuses	apparatus	NOUN
admet-801	155	5	are	be	AUX
admet-801	155	6	currently	currently	ADV
admet-801	155	7	the	the	DET
admet-801	155	8	most	most	ADV
admet-801	155	9	popular	popular	ADJ
admet-801	155	10	methods	method	NOUN
admet-801	155	11	,	,	PUNCT
admet-801	155	12	gao	gao	PROPN
admet-801	156	1	[	[	X
admet-801	156	2	33	33	NUM
admet-801	156	3	]	]	PUNCT
admet-801	156	4	explains	explain	VERB
admet-801	156	5	that	that	SCONJ
admet-801	156	6	both	both	DET
admet-801	156	7	methods	method	NOUN
admet-801	156	8	are	be	AUX
admet-801	156	9	operated	operate	VERB
admet-801	156	10	under	under	ADP
admet-801	156	11	closed	close	VERB
admet-801	156	12	finite	finite	ADJ
admet-801	156	13	sink	sink	NOUN
admet-801	156	14	conditions	condition	NOUN
admet-801	156	15	and	and	CCONJ
admet-801	156	16	can	can	AUX
admet-801	156	17	not	not	PART
admet-801	156	18	mimic	mimic	VERB
admet-801	156	19	the	the	DET
admet-801	156	20	conditions	condition	NOUN
admet-801	156	21	in	in	ADP
admet-801	156	22	the	the	DET
admet-801	156	23	gastrointestinal	gastrointestinal	ADJ
admet-801	156	24	tract	tract	NOUN
admet-801	156	25	.	.	PUNCT
admet-801	157	1	the	the	DET
admet-801	157	2	flow	flow	NOUN
admet-801	157	3	-	-	PUNCT
admet-801	157	4	through	through	ADP
admet-801	157	5	cell	cell	NOUN
admet-801	157	6	method	method	NOUN
admet-801	157	7	has	have	AUX
admet-801	157	8	gained	gain	VERB
admet-801	157	9	recent	recent	ADJ
admet-801	157	10	acceptance	acceptance	NOUN
admet-801	157	11	into	into	ADP
admet-801	157	12	the	the	DET
admet-801	157	13	dissolution	dissolution	NOUN
admet-801	157	14	field	field	NOUN
admet-801	157	15	for	for	ADP
admet-801	157	16	its	its	PRON
admet-801	157	17	versatility	versatility	NOUN
admet-801	157	18	in	in	ADP
admet-801	157	19	the	the	DET
admet-801	157	20	testing	testing	NOUN
admet-801	157	21	of	of	ADP
admet-801	157	22	novel	novel	ADJ
admet-801	157	23	dosage	dosage	NOUN
admet-801	157	24	forms	form	NOUN
admet-801	157	25	where	where	SCONJ
admet-801	157	26	traditional	traditional	ADJ
admet-801	157	27	dissolution	dissolution	NOUN
admet-801	157	28	apparatuses	apparatus	NOUN
admet-801	157	29	and	and	CCONJ
admet-801	157	30	methods	method	NOUN
admet-801	157	31	have	have	AUX
admet-801	157	32	failed	fail	VERB
admet-801	157	33	[	[	X
admet-801	157	34	34	34	NUM
admet-801	157	35	]	]	PUNCT
admet-801	157	36	.	.	PUNCT
admet-801	158	1	usp	usp	PROPN
admet-801	158	2	apparatus	apparatus	PROPN
admet-801	158	3	4	4	NUM
admet-801	158	4	has	have	VERB
admet-801	158	5	several	several	ADJ
admet-801	158	6	advantages	advantage	NOUN
admet-801	158	7	:	:	PUNCT
admet-801	158	8	1	1	X
admet-801	158	9	.	.	X
admet-801	158	10	sink	sink	NOUN
admet-801	158	11	conditions	condition	NOUN
admet-801	158	12	can	can	AUX
admet-801	158	13	be	be	AUX
admet-801	158	14	maintained	maintain	VERB
admet-801	158	15	for	for	ADP
admet-801	158	16	poorly	poorly	ADV
admet-801	158	17	soluble	soluble	ADJ
admet-801	158	18	drugs	drug	NOUN
admet-801	158	19	throughout	throughout	ADP
admet-801	158	20	the	the	DET
admet-801	158	21	dissolution	dissolution	NOUN
admet-801	158	22	run	run	NOUN
admet-801	158	23	;	;	PUNCT
admet-801	159	1	2	2	X
admet-801	159	2	.	.	X
admet-801	159	3	it	it	PRON
admet-801	159	4	is	be	AUX
admet-801	159	5	easy	easy	ADJ
admet-801	159	6	to	to	PART
admet-801	159	7	change	change	VERB
admet-801	159	8	media	medium	NOUN
admet-801	159	9	(	(	PUNCT
admet-801	159	10	suggested	suggest	VERB
admet-801	159	11	media	medium	NOUN
admet-801	159	12	is	be	AUX
admet-801	159	13	physiological	physiological	ADJ
admet-801	159	14	ph	ph	NOUN
admet-801	159	15	range	range	NOUN
admet-801	159	16	)	)	PUNCT
admet-801	159	17	and	and	CCONJ
admet-801	159	18	modify	modify	VERB
admet-801	159	19	flow	flow	NOUN
admet-801	159	20	rate	rate	NOUN
admet-801	159	21	to	to	PART
admet-801	159	22	simulate	simulate	VERB
admet-801	159	23	in	in	ADP
admet-801	159	24	vivo	vivo	ADJ
admet-801	159	25	conditions	condition	NOUN
admet-801	159	26	;	;	PUNCT
admet-801	159	27	3	3	X
admet-801	159	28	.	.	X
admet-801	160	1	it	it	PRON
admet-801	160	2	simulates	simulate	VERB
admet-801	160	3	intraluminal	intraluminal	ADJ
admet-801	160	4	hydrodynamics	hydrodynamic	NOUN
admet-801	160	5	efficiently	efficiently	ADV
admet-801	160	6	;	;	PUNCT
admet-801	161	1	4	4	X
admet-801	161	2	.	.	X
admet-801	162	1	it	it	PRON
admet-801	162	2	can	can	AUX
admet-801	162	3	be	be	AUX
admet-801	162	4	modified	modify	VERB
admet-801	162	5	for	for	ADP
admet-801	162	6	different	different	ADJ
admet-801	162	7	dosage	dosage	NOUN
admet-801	162	8	forms	form	NOUN
admet-801	162	9	;	;	PUNCT
admet-801	162	10	and	and	CCONJ
admet-801	162	11	5	5	X
admet-801	162	12	.	.	X
admet-801	162	13	it	it	PRON
admet-801	162	14	measures	measure	VERB
admet-801	162	15	the	the	DET
admet-801	162	16	in	in	ADV
admet-801	162	17	vitro	vitro	X
admet-801	162	18	release	release	NOUN
admet-801	162	19	rate	rate	NOUN
admet-801	162	20	profile	profile	NOUN
admet-801	162	21	as	as	ADP
admet-801	162	22	an	an	DET
admet-801	162	23	output	output	NOUN
admet-801	162	24	that	that	PRON
admet-801	162	25	is	be	AUX
admet-801	162	26	similar	similar	ADJ
admet-801	162	27	to	to	ADP
admet-801	162	28	the	the	DET
admet-801	162	29	shape	shape	NOUN
admet-801	162	30	of	of	ADP
admet-801	162	31	an	an	DET
admet-801	162	32	in	in	ADP
admet-801	162	33	vivo	vivo	NOUN
admet-801	162	34	profile	profile	NOUN
admet-801	162	35	[	[	X
admet-801	162	36	35	35	NUM
admet-801	162	37	]	]	PUNCT
admet-801	162	38	.	.	PUNCT
admet-801	163	1	american	american	PROPN
admet-801	163	2	and	and	CCONJ
admet-801	163	3	european	european	ADJ
admet-801	163	4	pharmacopoeias	pharmacopoeia	NOUN
admet-801	163	5	suggest	suggest	VERB
admet-801	163	6	three	three	NUM
admet-801	163	7	flow	flow	NOUN
admet-801	163	8	rates	rate	NOUN
admet-801	163	9	for	for	ADP
admet-801	163	10	testing	testing	NOUN
admet-801	163	11	with	with	ADP
admet-801	163	12	usp	usp	NOUN
admet-801	163	13	apparatus	apparatus	NOUN
admet-801	163	14	4	4	NUM
admet-801	163	15	(	(	PUNCT
admet-801	163	16	4	4	NUM
admet-801	163	17	,	,	PUNCT
admet-801	163	18	8	8	NUM
admet-801	163	19	,	,	PUNCT
admet-801	163	20	and	and	CCONJ
admet-801	163	21	16	16	NUM
admet-801	163	22	ml	ml	NOUN
admet-801	163	23	/	/	SYM
admet-801	163	24	min	min	NOUN
admet-801	163	25	)	)	PUNCT
admet-801	164	1	[	[	X
admet-801	164	2	36	36	NUM
admet-801	164	3	]	]	PUNCT
admet-801	164	4	.	.	PUNCT
admet-801	165	1	in	in	ADP
admet-801	165	2	this	this	PRON
admet-801	165	3	in	in	ADP
admet-801	165	4	vitro	vitro	X
admet-801	165	5	release	release	NOUN
admet-801	165	6	study	study	NOUN
admet-801	165	7	of	of	ADP
admet-801	165	8	furosemide	furosemide	ADJ
admet-801	165	9	reference	reference	NOUN
admet-801	165	10	tablets	tablet	NOUN
admet-801	165	11	,	,	PUNCT
admet-801	165	12	we	we	PRON
admet-801	165	13	used	use	VERB
admet-801	165	14	only	only	ADV
admet-801	165	15	the	the	DET
admet-801	165	16	flow	flow	NOUN
admet-801	165	17	rate	rate	NOUN
admet-801	165	18	of	of	ADP
admet-801	165	19	16	16	NUM
admet-801	165	20	ml	ml	NOUN
admet-801	165	21	/	/	SYM
admet-801	165	22	min	min	NOUN
admet-801	165	23	as	as	ADP
admet-801	165	24	the	the	DET
admet-801	165	25	sotax	sotax	NOUN
admet-801	165	26	equipment	equipment	NOUN
admet-801	165	27	model	model	NOUN
admet-801	165	28	ce6	ce6	VERB
admet-801	165	29	has	have	VERB
admet-801	165	30	a	a	DET
admet-801	165	31	working	work	VERB
admet-801	165	32	flow	flow	NOUN
admet-801	165	33	range	range	NOUN
admet-801	165	34	of	of	ADP
admet-801	165	35	10‒50	10‒50	NUM
admet-801	165	36	ml	ml	NOUN
admet-801	165	37	/	/	SYM
admet-801	165	38	min	min	NOUN
admet-801	165	39	.	.	PROPN
admet-801	165	40	based	base	VERB
admet-801	165	41	on	on	ADP
admet-801	165	42	these	these	DET
admet-801	165	43	characteristics	characteristic	NOUN
admet-801	165	44	,	,	PUNCT
admet-801	165	45	it	it	PRON
admet-801	165	46	is	be	AUX
admet-801	165	47	possible	possible	ADJ
admet-801	165	48	to	to	PART
admet-801	165	49	establish	establish	VERB
admet-801	165	50	a	a	DET
admet-801	165	51	meaningful	meaningful	ADJ
admet-801	165	52	ivivc	ivivc	NOUN
admet-801	165	53	with	with	ADP
admet-801	165	54	usp	usp	NOUN
admet-801	165	55	apparatus	apparatus	NOUN
admet-801	165	56	4	4	NUM
admet-801	165	57	.	.	PUNCT
admet-801	165	58	when	when	SCONJ
admet-801	165	59	a	a	DET
admet-801	165	60	meaningful	meaningful	ADJ
admet-801	165	61	ivivc	ivivc	NOUN
admet-801	165	62	has	have	AUX
admet-801	165	63	been	be	AUX
admet-801	165	64	established	establish	VERB
admet-801	165	65	,	,	PUNCT
admet-801	165	66	it	it	PRON
admet-801	165	67	can	can	AUX
admet-801	165	68	be	be	AUX
admet-801	165	69	used	use	VERB
admet-801	165	70	as	as	ADP
admet-801	165	71	a	a	DET
admet-801	165	72	surrogate	surrogate	NOUN
admet-801	165	73	for	for	ADP
admet-801	165	74	and	and	CCONJ
admet-801	165	75	to	to	PART
admet-801	165	76	minimize	minimize	VERB
admet-801	165	77	the	the	DET
admet-801	165	78	number	number	NOUN
admet-801	165	79	of	of	ADP
admet-801	165	80	bioequivalence	bioequivalence	NOUN
admet-801	165	81	studies	study	NOUN
admet-801	165	82	during	during	ADP
admet-801	165	83	drug	drug	NOUN
admet-801	165	84	product	product	NOUN
admet-801	165	85	development	development	NOUN
admet-801	165	86	[	[	X
admet-801	165	87	37	37	NUM
admet-801	165	88	]	]	PUNCT
admet-801	165	89	.	.	PUNCT
admet-801	166	1	some	some	DET
admet-801	166	2	authors	author	NOUN
admet-801	166	3	have	have	AUX
admet-801	166	4	reported	report	VERB
admet-801	166	5	a	a	DET
admet-801	166	6	better	well	ADJ
admet-801	166	7	estimate	estimate	NOUN
admet-801	166	8	of	of	ADP
admet-801	166	9	the	the	DET
admet-801	166	10	absorption	absorption	NOUN
admet-801	166	11	rate	rate	NOUN
admet-801	166	12	of	of	ADP
admet-801	166	13	cilostazol	cilostazol	ADJ
admet-801	166	14	[	[	X
admet-801	166	15	19	19	NUM
admet-801	166	16	]	]	PUNCT
admet-801	166	17	and	and	CCONJ
admet-801	166	18	diclofenac	diclofenac	ADJ
admet-801	166	19	sodium	sodium	NOUN
admet-801	166	20	[	[	X
admet-801	166	21	20	20	NUM
admet-801	166	22	]	]	SYM
admet-801	166	23	formulations	formulation	NOUN
admet-801	166	24	,	,	PUNCT
admet-801	166	25	both	both	DET
admet-801	166	26	drugs	drug	NOUN
admet-801	166	27	with	with	ADP
admet-801	166	28	solubility	solubility	NOUN
admet-801	166	29	problems	problem	NOUN
admet-801	166	30	,	,	PUNCT
admet-801	166	31	with	with	ADP
admet-801	166	32	the	the	DET
admet-801	166	33	flow	flow	NOUN
admet-801	166	34	-	-	PUNCT
admet-801	166	35	through	through	ADP
admet-801	166	36	cell	cell	NOUN
admet-801	166	37	method	method	NOUN
admet-801	166	38	.	.	PUNCT
admet-801	167	1	some	some	DET
admet-801	167	2	drugs	drug	NOUN
admet-801	167	3	can	can	AUX
admet-801	167	4	be	be	AUX
admet-801	167	5	dissolved	dissolve	VERB
admet-801	167	6	using	use	VERB
admet-801	167	7	dissolution	dissolution	ADJ
admet-801	167	8	media	medium	NOUN
admet-801	167	9	in	in	ADP
admet-801	167	10	the	the	DET
admet-801	167	11	physiological	physiological	ADJ
admet-801	167	12	ph	ph	NOUN
admet-801	167	13	range	range	NOUN
admet-801	167	14	(	(	PUNCT
admet-801	167	15	ph	ph	NOUN
admet-801	167	16	1.2	1.2	NUM
admet-801	167	17	,	,	PUNCT
admet-801	167	18	4.5	4.5	NUM
admet-801	167	19	,	,	PUNCT
admet-801	167	20	and	and	CCONJ
admet-801	167	21	6.8	6.8	NUM
admet-801	167	22	)	)	PUNCT
admet-801	167	23	or	or	CCONJ
admet-801	167	24	biorelevant	biorelevant	ADJ
admet-801	167	25	media	medium	NOUN
admet-801	167	26	,	,	PUNCT
admet-801	167	27	such	such	ADJ
admet-801	167	28	as	as	ADP
admet-801	167	29	fassif	fassif	NOUN
admet-801	167	30	and	and	CCONJ
admet-801	167	31	fessif	fessif	NOUN
admet-801	167	32	(	(	PUNCT
admet-801	167	33	media	medium	NOUN
admet-801	167	34	that	that	PRON
admet-801	167	35	simulate	simulate	VERB
admet-801	167	36	the	the	DET
admet-801	167	37	absence	absence	NOUN
admet-801	167	38	or	or	CCONJ
admet-801	167	39	presence	presence	NOUN
admet-801	167	40	of	of	ADP
admet-801	167	41	food	food	NOUN
admet-801	167	42	,	,	PUNCT
admet-801	167	43	respectively	respectively	ADV
admet-801	167	44	)	)	PUNCT
admet-801	168	1	[	[	X
admet-801	168	2	38	38	NUM
admet-801	168	3	]	]	PUNCT
admet-801	168	4	,	,	PUNCT
admet-801	168	5	to	to	PART
admet-801	168	6	document	document	VERB
admet-801	168	7	the	the	DET
admet-801	168	8	release	release	NOUN
admet-801	168	9	performance	performance	NOUN
admet-801	168	10	of	of	ADP
admet-801	168	11	oral	oral	ADJ
admet-801	168	12	dosage	dosage	NOUN
admet-801	168	13	forms	form	NOUN
admet-801	168	14	through	through	ADP
admet-801	168	15	the	the	DET
admet-801	168	16	gastrointestinal	gastrointestinal	ADJ
admet-801	168	17	tract	tract	NOUN
admet-801	168	18	.	.	PUNCT
admet-801	169	1	this	this	PRON
admet-801	169	2	is	be	AUX
admet-801	169	3	especially	especially	ADV
admet-801	169	4	important	important	ADJ
admet-801	169	5	with	with	ADP
admet-801	169	6	poorly	poorly	ADV
admet-801	169	7	soluble	soluble	ADJ
admet-801	169	8	drugs	drug	NOUN
admet-801	169	9	,	,	PUNCT
admet-801	169	10	such	such	ADJ
admet-801	169	11	as	as	ADP
admet-801	169	12	furosemide	furosemide	ADJ
admet-801	169	13	.	.	PUNCT
admet-801	170	1	based	base	VERB
admet-801	170	2	on	on	ADP
admet-801	170	3	the	the	DET
admet-801	170	4	physicochemical	physicochemical	ADJ
admet-801	170	5	characteristics	characteristic	NOUN
admet-801	170	6	of	of	ADP
admet-801	170	7	this	this	DET
admet-801	170	8	drug	drug	NOUN
admet-801	170	9	,	,	PUNCT
admet-801	170	10	dissolution	dissolution	NOUN
admet-801	170	11	at	at	ADP
admet-801	170	12	low	low	ADJ
admet-801	170	13	ph	ph	NOUN
admet-801	170	14	is	be	AUX
admet-801	170	15	not	not	PART
admet-801	170	16	physiologically	physiologically	ADV
admet-801	170	17	relevant	relevant	ADJ
admet-801	170	18	.	.	PUNCT
admet-801	171	1	for	for	ADP
admet-801	171	2	a	a	DET
admet-801	171	3	complete	complete	ADJ
admet-801	171	4	dissolution	dissolution	NOUN
admet-801	171	5	scheme	scheme	NOUN
admet-801	171	6	in	in	ADP
admet-801	171	7	a	a	DET
admet-801	171	8	physiological	physiological	ADJ
admet-801	171	9	ph	ph	NOUN
admet-801	171	10	range	range	NOUN
admet-801	171	11	,	,	PUNCT
admet-801	171	12	the	the	DET
admet-801	171	13	food	food	NOUN
admet-801	171	14	and	and	CCONJ
admet-801	171	15	drug	drug	NOUN
admet-801	171	16	administration	administration	NOUN
admet-801	171	17	recommends	recommend	VERB
admet-801	171	18	dissolution	dissolution	NOUN
admet-801	171	19	tests	test	NOUN
admet-801	171	20	with	with	ADP
admet-801	171	21	a	a	DET
admet-801	171	22	0.1	0.1	NUM
admet-801	171	23	n	n	PRON
admet-801	171	24	hydrochloric	hydrochloric	ADJ
admet-801	171	25	acid	acid	NOUN
admet-801	171	26	or	or	CCONJ
admet-801	171	27	simulated	simulate	VERB
admet-801	171	28	gastric	gastric	ADJ
admet-801	171	29	fluid	fluid	NOUN
admet-801	171	30	usp	usp	NOUN
admet-801	171	31	without	without	ADP
admet-801	171	32	enzymes	enzyme	NOUN
admet-801	171	33	,	,	PUNCT
admet-801	171	34	ph	ph	NOUN
admet-801	171	35	4.5	4.5	NUM
admet-801	171	36	or	or	CCONJ
admet-801	171	37	ph	ph	ADJ
admet-801	171	38	6.8	6.8	NUM
admet-801	171	39	buffer	buffer	NOUN
admet-801	171	40	,	,	PUNCT
admet-801	171	41	or	or	CCONJ
admet-801	171	42	simulated	simulate	VERB
admet-801	171	43	intestinal	intestinal	ADJ
admet-801	171	44	fluid	fluid	NOUN
admet-801	171	45	usp	usp	NOUN
admet-801	171	46	without	without	ADP
admet-801	171	47	enzymes	enzyme	NOUN
admet-801	171	48	[	[	X
admet-801	171	49	39	39	NUM
admet-801	171	50	]	]	PUNCT
admet-801	171	51	.	.	PUNCT
admet-801	172	1	the	the	DET
admet-801	172	2	dissolution	dissolution	NOUN
admet-801	172	3	of	of	ADP
admet-801	172	4	furosemide	furosemide	ADJ
admet-801	172	5	reference	reference	NOUN
admet-801	172	6	tablets	tablet	NOUN
admet-801	172	7	was	be	AUX
admet-801	172	8	carried	carry	VERB
admet-801	172	9	out	out	ADP
admet-801	172	10	under	under	ADP
admet-801	172	11	these	these	DET
admet-801	172	12	conditions	condition	NOUN
admet-801	172	13	,	,	PUNCT
admet-801	172	14	with	with	ADP
admet-801	172	15	the	the	DET
admet-801	172	16	exception	exception	NOUN
admet-801	172	17	of	of	ADP
admet-801	172	18	simulated	simulated	ADJ
admet-801	172	19	fluids	fluid	NOUN
admet-801	172	20	,	,	PUNCT
admet-801	172	21	and	and	CCONJ
admet-801	172	22	the	the	DET
admet-801	172	23	best	good	ADJ
admet-801	172	24	results	result	NOUN
admet-801	172	25	were	be	AUX
admet-801	172	26	observed	observe	VERB
admet-801	172	27	with	with	ADP
admet-801	172	28	phosphate	phosphate	ADJ
admet-801	172	29	buffers	buffer	NOUN
admet-801	172	30	at	at	ADP
admet-801	172	31	ph	ph	PROPN
admet-801	172	32	5.8	5.8	NUM
admet-801	172	33	and	and	CCONJ
admet-801	172	34	ph	ph	ADJ
admet-801	172	35	6.8	6.8	NUM
admet-801	172	36	.	.	PUNCT
admet-801	173	1	more	more	ADJ
admet-801	173	2	than	than	ADP
admet-801	173	3	80	80	NUM
admet-801	173	4	%	%	NOUN
admet-801	173	5	of	of	ADP
admet-801	173	6	the	the	DET
admet-801	173	7	drug	drug	NOUN
admet-801	173	8	dissolved	dissolve	VERB
admet-801	173	9	at	at	ADP
admet-801	173	10	60	60	NUM
admet-801	173	11	min	min	NOUN
admet-801	173	12	and	and	CCONJ
admet-801	173	13	time	time	NOUN
admet-801	173	14	parameters	parameter	NOUN
admet-801	173	15	,	,	PUNCT
admet-801	173	16	such	such	ADJ
admet-801	173	17	as	as	ADP
admet-801	173	18	mdt	mdt	PROPN
admet-801	173	19	,	,	PUNCT
admet-801	173	20	t50	t50	NOUN
admet-801	173	21	%	%	NOUN
admet-801	173	22	,	,	PUNCT
admet-801	173	23	and	and	CCONJ
admet-801	173	24	t80	t80	PROPN
admet-801	173	25	%	%	NOUN
admet-801	173	26	were	be	AUX
admet-801	173	27	calculated	calculate	VERB
admet-801	173	28	.	.	PUNCT
admet-801	174	1	at	at	ADP
admet-801	174	2	50	50	NUM
admet-801	174	3	rpm	rpm	NOUN
admet-801	174	4	,	,	PUNCT
admet-801	174	5	significant	significant	ADJ
admet-801	174	6	differences	difference	NOUN
admet-801	174	7	in	in	ADP
admet-801	174	8	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	ADJ
admet-801	174	9	medina	medina	PROPN
admet-801	174	10	-	-	PUNCT
admet-801	174	11	lópez	lópez	PROPN
admet-801	174	12	et	et	PROPN
admet-801	174	13	al	al	PROPN
admet-801	174	14	.	.	PROPN
admet-801	174	15	admet	admet	PROPN
admet-801	174	16	&	&	CCONJ
admet-801	174	17	dmpk	dmpk	PROPN
admet-801	174	18	8(4	8(4	NOUN
admet-801	174	19	)	)	PUNCT
admet-801	174	20	(	(	PUNCT
admet-801	174	21	2020	2020	NUM
admet-801	174	22	)	)	PUNCT
admet-801	174	23	411	411	NUM
admet-801	174	24	-	-	SYM
admet-801	174	25	423	423	NUM
admet-801	174	26	420	420	NUM
admet-801	174	27	all	all	DET
admet-801	174	28	calculated	calculated	ADJ
admet-801	174	29	parameters	parameter	NOUN
admet-801	174	30	(	(	PUNCT
admet-801	174	31	usp	usp	NOUN
admet-801	174	32	apparatus	apparatus	NOUN
admet-801	174	33	1	1	NUM
admet-801	174	34	vs.	vs.	ADP
admet-801	174	35	2	2	NUM
admet-801	174	36	)	)	PUNCT
admet-801	174	37	were	be	AUX
admet-801	174	38	observed	observe	VERB
admet-801	174	39	.	.	PUNCT
admet-801	175	1	differences	difference	NOUN
admet-801	175	2	between	between	ADP
admet-801	175	3	both	both	DET
admet-801	175	4	usp	usp	NOUN
admet-801	175	5	apparatuses	apparatus	NOUN
admet-801	175	6	were	be	AUX
admet-801	175	7	expected	expect	VERB
admet-801	175	8	owing	owe	VERB
admet-801	175	9	to	to	ADP
admet-801	175	10	the	the	DET
admet-801	175	11	different	different	ADJ
admet-801	175	12	hydrodynamics	hydrodynamic	NOUN
admet-801	175	13	of	of	ADP
admet-801	175	14	each	each	DET
admet-801	175	15	apparatus	apparatus	NOUN
admet-801	175	16	;	;	PUNCT
admet-801	175	17	however	however	ADV
admet-801	175	18	,	,	PUNCT
admet-801	175	19	it	it	PRON
admet-801	175	20	is	be	AUX
admet-801	175	21	necessary	necessary	ADJ
admet-801	175	22	to	to	PART
admet-801	175	23	understand	understand	VERB
admet-801	175	24	at	at	ADP
admet-801	175	25	what	what	PRON
admet-801	175	26	agitation	agitation	NOUN
admet-801	175	27	rate	rate	NOUN
admet-801	175	28	this	this	DET
admet-801	175	29	difference	difference	NOUN
admet-801	175	30	is	be	AUX
admet-801	175	31	more	more	ADV
admet-801	175	32	evident	evident	ADJ
admet-801	175	33	.	.	PUNCT
admet-801	176	1	despite	despite	SCONJ
admet-801	176	2	the	the	DET
admet-801	176	3	wide	wide	ADJ
admet-801	176	4	use	use	NOUN
admet-801	176	5	of	of	ADP
admet-801	176	6	usp	usp	NOUN
admet-801	176	7	apparatuses	apparatus	NOUN
admet-801	176	8	1	1	NUM
admet-801	176	9	and	and	CCONJ
admet-801	176	10	2	2	NUM
admet-801	176	11	at	at	ADP
admet-801	176	12	different	different	ADJ
admet-801	176	13	agitation	agitation	NOUN
admet-801	176	14	rates	rate	NOUN
admet-801	176	15	,	,	PUNCT
admet-801	176	16	they	they	PRON
admet-801	176	17	have	have	AUX
admet-801	176	18	still	still	ADV
admet-801	176	19	been	be	AUX
admet-801	176	20	evaluated	evaluate	VERB
admet-801	176	21	by	by	ADP
admet-801	176	22	several	several	ADJ
admet-801	176	23	authors	author	NOUN
admet-801	176	24	in	in	ADP
admet-801	176	25	terms	term	NOUN
admet-801	176	26	of	of	ADP
admet-801	176	27	the	the	DET
admet-801	176	28	surrounding	surround	VERB
admet-801	176	29	hydrodynamic	hydrodynamic	ADJ
admet-801	176	30	environments	environment	NOUN
admet-801	176	31	,	,	PUNCT
admet-801	176	32	which	which	PRON
admet-801	176	33	do	do	AUX
admet-801	176	34	not	not	PART
admet-801	176	35	adequately	adequately	ADV
admet-801	176	36	reproduce	reproduce	VERB
admet-801	176	37	the	the	DET
admet-801	176	38	natural	natural	ADJ
admet-801	176	39	environment	environment	NOUN
admet-801	176	40	of	of	ADP
admet-801	176	41	the	the	DET
admet-801	176	42	gastrointestinal	gastrointestinal	ADJ
admet-801	176	43	tract	tract	NOUN
admet-801	176	44	[	[	X
admet-801	176	45	13	13	NUM
admet-801	176	46	-	-	SYM
admet-801	176	47	15,32,40	15,32,40	NUM
admet-801	176	48	]	]	PUNCT
admet-801	176	49	.	.	PUNCT
admet-801	177	1	the	the	DET
admet-801	177	2	fitting	fitting	NOUN
admet-801	177	3	of	of	ADP
admet-801	177	4	dissolution	dissolution	ADJ
admet-801	177	5	data	datum	NOUN
admet-801	177	6	to	to	ADP
admet-801	177	7	mathematical	mathematical	ADJ
admet-801	177	8	models	model	NOUN
admet-801	177	9	was	be	AUX
admet-801	177	10	carried	carry	VERB
admet-801	177	11	out	out	ADP
admet-801	177	12	without	without	ADP
admet-801	177	13	any	any	DET
admet-801	177	14	physiological	physiological	ADJ
admet-801	177	15	significance	significance	NOUN
admet-801	177	16	to	to	PART
admet-801	177	17	discover	discover	VERB
admet-801	177	18	the	the	DET
admet-801	177	19	best	good	ADJ
admet-801	177	20	equation	equation	NOUN
admet-801	177	21	to	to	PART
admet-801	177	22	explain	explain	VERB
admet-801	177	23	the	the	DET
admet-801	177	24	in	in	ADV
admet-801	177	25	vitro	vitro	X
admet-801	177	26	release	release	NOUN
admet-801	177	27	performance	performance	NOUN
admet-801	177	28	of	of	ADP
admet-801	177	29	furosemide	furosemide	ADJ
admet-801	177	30	reference	reference	NOUN
admet-801	177	31	tablets	tablet	NOUN
admet-801	177	32	.	.	PUNCT
admet-801	178	1	these	these	DET
admet-801	178	2	models	model	NOUN
admet-801	178	3	were	be	AUX
admet-801	178	4	used	use	VERB
admet-801	178	5	to	to	PART
admet-801	178	6	facilitate	facilitate	VERB
admet-801	178	7	the	the	DET
admet-801	178	8	analysis	analysis	NOUN
admet-801	178	9	and	and	CCONJ
admet-801	178	10	interpretation	interpretation	NOUN
admet-801	178	11	of	of	ADP
admet-801	178	12	dissolution	dissolution	NOUN
admet-801	178	13	data	datum	NOUN
admet-801	178	14	because	because	SCONJ
admet-801	178	15	they	they	PRON
admet-801	178	16	describe	describe	VERB
admet-801	178	17	the	the	DET
admet-801	178	18	dissolution	dissolution	NOUN
admet-801	178	19	profiles	profile	NOUN
admet-801	178	20	as	as	ADP
admet-801	178	21	a	a	DET
admet-801	178	22	function	function	NOUN
admet-801	178	23	of	of	ADP
admet-801	178	24	the	the	DET
admet-801	178	25	few	few	ADJ
admet-801	178	26	parameters	parameter	NOUN
admet-801	178	27	that	that	PRON
admet-801	178	28	can	can	AUX
admet-801	178	29	be	be	AUX
admet-801	178	30	statistically	statistically	ADV
admet-801	178	31	compared	compare	VERB
admet-801	178	32	[	[	X
admet-801	178	33	41	41	NUM
admet-801	178	34	]	]	PUNCT
admet-801	178	35	.	.	PUNCT
admet-801	179	1	han	han	PROPN
admet-801	179	2	et	et	PROPN
admet-801	179	3	al	al	PROPN
admet-801	179	4	.	.	PUNCT
admet-801	180	1	[	[	X
admet-801	180	2	42	42	NUM
admet-801	180	3	]	]	PUNCT
admet-801	180	4	documented	document	VERB
admet-801	180	5	the	the	DET
admet-801	180	6	first	first	ADJ
admet-801	180	7	-	-	PUNCT
admet-801	180	8	order	order	NOUN
admet-801	180	9	kinetics	kinetic	NOUN
admet-801	180	10	as	as	ADP
admet-801	180	11	the	the	DET
admet-801	180	12	best	good	ADJ
admet-801	180	13	-	-	PUNCT
admet-801	180	14	fit	fit	ADJ
admet-801	180	15	model	model	NOUN
admet-801	180	16	to	to	PART
admet-801	180	17	adjust	adjust	VERB
admet-801	180	18	furosemide	furosemide	ADJ
admet-801	180	19	dissolution	dissolution	PROPN
admet-801	180	20	data	datum	NOUN
admet-801	180	21	from	from	ADP
admet-801	180	22	commercial	commercial	ADJ
admet-801	180	23	tablets	tablet	NOUN
admet-801	180	24	;	;	PUNCT
admet-801	180	25	however	however	ADV
admet-801	180	26	,	,	PUNCT
admet-801	180	27	an	an	DET
admet-801	180	28	incomplete	incomplete	ADJ
admet-801	180	29	fit	fit	ADJ
admet-801	180	30	scheme	scheme	NOUN
admet-801	180	31	was	be	AUX
admet-801	180	32	created	create	VERB
admet-801	180	33	as	as	ADP
admet-801	180	34	only	only	ADV
admet-801	180	35	zero	zero	NUM
admet-801	180	36	-	-	PUNCT
admet-801	180	37	order	order	NOUN
admet-801	180	38	and	and	CCONJ
admet-801	180	39	first	first	ADJ
admet-801	180	40	-	-	PUNCT
admet-801	180	41	order	order	NOUN
admet-801	180	42	kinetics	kinetic	NOUN
admet-801	180	43	were	be	AUX
admet-801	180	44	used	use	VERB
admet-801	180	45	to	to	PART
admet-801	180	46	adjust	adjust	VERB
admet-801	180	47	their	their	PRON
admet-801	180	48	dissolution	dissolution	NOUN
admet-801	180	49	data	datum	NOUN
admet-801	180	50	.	.	PUNCT
admet-801	181	1	in	in	ADP
admet-801	181	2	our	our	PRON
admet-801	181	3	study	study	NOUN
admet-801	181	4	,	,	PUNCT
admet-801	181	5	after	after	ADP
admet-801	181	6	testing	test	VERB
admet-801	181	7	several	several	ADJ
admet-801	181	8	equations	equation	NOUN
admet-801	181	9	(	(	PUNCT
admet-801	181	10	including	include	VERB
admet-801	181	11	common	common	ADJ
admet-801	181	12	dissolution	dissolution	NOUN
admet-801	181	13	kinetics	kinetic	NOUN
admet-801	181	14	)	)	PUNCT
admet-801	181	15	,	,	PUNCT
admet-801	181	16	weibull	weibull	PROPN
admet-801	181	17	function	function	PROPN
admet-801	181	18	was	be	AUX
admet-801	181	19	the	the	DET
admet-801	181	20	best	good	ADJ
admet-801	181	21	mathematical	mathematical	ADJ
admet-801	181	22	model	model	NOUN
admet-801	181	23	to	to	PART
admet-801	181	24	explain	explain	VERB
admet-801	181	25	the	the	DET
admet-801	181	26	dissolution	dissolution	ADJ
admet-801	181	27	performance	performance	NOUN
admet-801	181	28	of	of	ADP
admet-801	181	29	furosemide	furosemide	NOUN
admet-801	181	30	.	.	PUNCT
admet-801	182	1	the	the	DET
admet-801	182	2	development	development	NOUN
admet-801	182	3	of	of	ADP
admet-801	182	4	more	more	ADJ
admet-801	182	5	discriminative	discriminative	NOUN
admet-801	182	6	methods	method	NOUN
admet-801	182	7	than	than	ADP
admet-801	182	8	using	use	VERB
admet-801	182	9	pharmacopoeial	pharmacopoeial	ADJ
admet-801	182	10	conditions	condition	NOUN
admet-801	182	11	to	to	PART
admet-801	182	12	evaluate	evaluate	VERB
admet-801	182	13	the	the	DET
admet-801	182	14	biopharmaceutical	biopharmaceutical	ADJ
admet-801	182	15	quality	quality	NOUN
admet-801	182	16	of	of	ADP
admet-801	182	17	generic	generic	ADJ
admet-801	182	18	formulations	formulation	NOUN
admet-801	182	19	has	have	AUX
admet-801	182	20	been	be	AUX
admet-801	182	21	documented	document	VERB
admet-801	182	22	.	.	PUNCT
admet-801	183	1	studies	study	NOUN
admet-801	183	2	with	with	ADP
admet-801	183	3	class	class	NOUN
admet-801	183	4	ii	ii	NOUN
admet-801	183	5	drugs	drug	NOUN
admet-801	183	6	,	,	PUNCT
admet-801	183	7	such	such	ADJ
admet-801	183	8	as	as	ADP
admet-801	183	9	carbamazepine	carbamazepine	NOUN
admet-801	183	10	[	[	X
admet-801	183	11	43	43	NUM
admet-801	183	12	]	]	PUNCT
admet-801	183	13	,	,	PUNCT
admet-801	183	14	meloxicam	meloxicam	NOUN
admet-801	184	1	[	[	X
admet-801	184	2	44	44	NUM
admet-801	184	3	]	]	PUNCT
admet-801	184	4	,	,	PUNCT
admet-801	184	5	and	and	CCONJ
admet-801	184	6	naproxen	naproxen	NOUN
admet-801	184	7	sodium	sodium	NOUN
admet-801	185	1	[	[	X
admet-801	185	2	45	45	NUM
admet-801	185	3	]	]	PUNCT
admet-801	185	4	,	,	PUNCT
admet-801	185	5	tested	test	VERB
admet-801	185	6	with	with	ADP
admet-801	185	7	usp	usp	NOUN
admet-801	185	8	apparatuses	apparatus	NOUN
admet-801	185	9	2	2	NUM
admet-801	185	10	and	and	CCONJ
admet-801	185	11	4	4	NUM
admet-801	185	12	have	have	AUX
admet-801	185	13	shown	show	VERB
admet-801	185	14	that	that	SCONJ
admet-801	185	15	usp	usp	NOUN
admet-801	185	16	apparatus	apparatus	NOUN
admet-801	185	17	2	2	NUM
admet-801	185	18	may	may	AUX
admet-801	185	19	not	not	PART
admet-801	185	20	reflect	reflect	VERB
admet-801	185	21	the	the	DET
admet-801	185	22	dissolution	dissolution	ADJ
admet-801	185	23	performance	performance	NOUN
admet-801	185	24	of	of	ADP
admet-801	185	25	generic	generic	ADJ
admet-801	185	26	formulations	formulation	NOUN
admet-801	185	27	and	and	CCONJ
admet-801	185	28	references	reference	NOUN
admet-801	185	29	.	.	PUNCT
admet-801	186	1	the	the	DET
admet-801	186	2	choice	choice	NOUN
admet-801	186	3	of	of	ADP
admet-801	186	4	the	the	DET
admet-801	186	5	hydrodynamic	hydrodynamic	ADJ
admet-801	186	6	environment	environment	NOUN
admet-801	186	7	for	for	ADP
admet-801	186	8	the	the	DET
admet-801	186	9	drug	drug	NOUN
admet-801	186	10	release	release	NOUN
admet-801	186	11	is	be	AUX
admet-801	186	12	key	key	ADJ
admet-801	186	13	to	to	PART
admet-801	186	14	identify	identify	VERB
admet-801	186	15	a	a	DET
admet-801	186	16	meaningful	meaningful	ADJ
admet-801	186	17	ivivc	ivivc	NOUN
admet-801	186	18	[	[	X
admet-801	186	19	35	35	NUM
admet-801	186	20	]	]	PUNCT
admet-801	186	21	.	.	PUNCT
admet-801	187	1	for	for	ADP
admet-801	187	2	class	class	NOUN
admet-801	187	3	ii	ii	PROPN
admet-801	187	4	drugs	drug	NOUN
admet-801	187	5	,	,	PUNCT
admet-801	187	6	ivivcs	ivivcs	ADV
admet-801	187	7	have	have	AUX
admet-801	187	8	been	be	AUX
admet-801	187	9	identified	identify	VERB
admet-801	187	10	and	and	CCONJ
admet-801	187	11	,	,	PUNCT
admet-801	187	12	with	with	ADP
admet-801	187	13	in	in	ADP
admet-801	187	14	vitro	vitro	X
admet-801	187	15	studies	study	NOUN
admet-801	187	16	,	,	PUNCT
admet-801	187	17	they	they	PRON
admet-801	187	18	provide	provide	VERB
admet-801	187	19	a	a	DET
admet-801	187	20	good	good	ADJ
admet-801	187	21	estimate	estimate	NOUN
admet-801	187	22	of	of	ADP
admet-801	187	23	the	the	DET
admet-801	187	24	absorption	absorption	NOUN
admet-801	187	25	rate	rate	NOUN
admet-801	187	26	of	of	ADP
admet-801	187	27	class	class	NOUN
admet-801	187	28	ii	ii	NOUN
admet-801	187	29	drugs	drug	NOUN
admet-801	187	30	.	.	PUNCT
admet-801	188	1	several	several	ADJ
admet-801	188	2	authors	author	NOUN
admet-801	188	3	have	have	AUX
admet-801	188	4	shown	show	VERB
admet-801	188	5	this	this	DET
admet-801	188	6	important	important	ADJ
admet-801	188	7	association	association	NOUN
admet-801	188	8	only	only	ADV
admet-801	188	9	with	with	ADP
admet-801	188	10	usp	usp	NOUN
admet-801	188	11	apparatus	apparatus	NOUN
admet-801	188	12	4	4	NUM
admet-801	189	1	[	[	X
admet-801	189	2	19,20,35	19,20,35	NUM
admet-801	189	3	]	]	PUNCT
admet-801	189	4	.	.	PUNCT
admet-801	190	1	however	however	ADV
admet-801	190	2	,	,	PUNCT
admet-801	190	3	similar	similar	ADJ
admet-801	190	4	dissolution	dissolution	NOUN
admet-801	190	5	profiles	profile	NOUN
admet-801	190	6	for	for	ADP
admet-801	190	7	usp	usp	NOUN
admet-801	190	8	apparatuses	apparatus	NOUN
admet-801	190	9	2	2	NUM
admet-801	190	10	and	and	CCONJ
admet-801	190	11	4	4	NUM
admet-801	190	12	have	have	AUX
admet-801	190	13	been	be	AUX
admet-801	190	14	reported	report	VERB
admet-801	190	15	for	for	ADP
admet-801	190	16	naproxen	naproxen	NOUN
admet-801	190	17	sodium	sodium	NOUN
admet-801	190	18	tablets	tablet	NOUN
admet-801	190	19	[	[	X
admet-801	190	20	45	45	NUM
admet-801	190	21	]	]	PUNCT
admet-801	190	22	and	and	CCONJ
admet-801	190	23	ibuprofen	ibuprofen	PROPN
admet-801	190	24	suspensions	suspension	NOUN
admet-801	190	25	[	[	X
admet-801	190	26	46	46	NUM
admet-801	190	27	]	]	PUNCT
admet-801	190	28	.	.	PUNCT
admet-801	191	1	these	these	DET
admet-801	191	2	results	result	NOUN
admet-801	191	3	are	be	AUX
admet-801	191	4	important	important	ADJ
admet-801	191	5	where	where	SCONJ
admet-801	191	6	no	no	DET
admet-801	191	7	flow	flow	NOUN
admet-801	191	8	-	-	PUNCT
admet-801	191	9	through	through	ADP
admet-801	191	10	cell	cell	NOUN
admet-801	191	11	method	method	NOUN
admet-801	191	12	is	be	AUX
admet-801	191	13	available	available	ADJ
admet-801	191	14	,	,	PUNCT
admet-801	191	15	and	and	CCONJ
admet-801	191	16	an	an	DET
admet-801	191	17	equivalent	equivalent	ADJ
admet-801	191	18	hydrodynamic	hydrodynamic	ADJ
admet-801	191	19	environment	environment	NOUN
admet-801	191	20	is	be	AUX
admet-801	191	21	required	require	VERB
admet-801	191	22	to	to	PART
admet-801	191	23	test	test	VERB
admet-801	191	24	solid	solid	ADJ
admet-801	191	25	dosage	dosage	NOUN
admet-801	191	26	forms	form	NOUN
admet-801	191	27	.	.	PUNCT
admet-801	192	1	conclusions	conclusion	NOUN
admet-801	192	2	the	the	DET
admet-801	192	3	in	in	ADV
admet-801	192	4	vitro	vitro	X
admet-801	192	5	release	release	NOUN
admet-801	192	6	performance	performance	NOUN
admet-801	192	7	of	of	ADP
admet-801	192	8	furosemide	furosemide	ADJ
admet-801	192	9	reference	reference	NOUN
admet-801	192	10	tablets	tablet	NOUN
admet-801	192	11	was	be	AUX
admet-801	192	12	determined	determine	VERB
admet-801	192	13	using	use	VERB
admet-801	192	14	usp	usp	NOUN
admet-801	192	15	apparatuses	apparatus	NOUN
admet-801	192	16	1	1	NUM
admet-801	192	17	and	and	CCONJ
admet-801	192	18	2	2	NUM
admet-801	192	19	at	at	ADP
admet-801	192	20	different	different	ADJ
admet-801	192	21	agitation	agitation	NOUN
admet-801	192	22	rates	rate	NOUN
admet-801	192	23	and	and	CCONJ
admet-801	192	24	dissolution	dissolution	ADJ
admet-801	192	25	media	medium	NOUN
admet-801	192	26	of	of	ADP
admet-801	192	27	physiological	physiological	ADJ
admet-801	192	28	relevance	relevance	NOUN
admet-801	192	29	.	.	PUNCT
admet-801	193	1	a	a	DET
admet-801	193	2	limited	limited	ADJ
admet-801	193	3	amount	amount	NOUN
admet-801	193	4	of	of	ADP
admet-801	193	5	furosemide	furosemide	ADJ
admet-801	193	6	dissolved	dissolve	VERB
admet-801	193	7	with	with	ADP
admet-801	193	8	both	both	PRON
admet-801	193	9	at	at	ADP
admet-801	193	10	ph	ph	PROPN
admet-801	193	11	1.2	1.2	NUM
admet-801	193	12	and	and	CCONJ
admet-801	193	13	4.5	4.5	NUM
admet-801	193	14	.	.	PUNCT
admet-801	194	1	better	well	ADJ
admet-801	194	2	results	result	NOUN
admet-801	194	3	were	be	AUX
admet-801	194	4	obtained	obtain	VERB
admet-801	194	5	with	with	ADP
admet-801	194	6	a	a	DET
admet-801	194	7	dissolution	dissolution	ADJ
admet-801	194	8	medium	medium	NOUN
admet-801	194	9	of	of	ADP
admet-801	194	10	ph	ph	NOUN
admet-801	194	11	6.8	6.8	NUM
admet-801	194	12	.	.	PUNCT
admet-801	195	1	although	although	SCONJ
admet-801	195	2	usp	usp	NOUN
admet-801	195	3	basket	basket	NOUN
admet-801	195	4	and	and	CCONJ
admet-801	195	5	paddle	paddle	NOUN
admet-801	195	6	apparatuses	apparatus	NOUN
admet-801	195	7	are	be	AUX
admet-801	195	8	the	the	DET
admet-801	195	9	most	most	ADV
admet-801	195	10	widely	widely	ADV
admet-801	195	11	used	use	VERB
admet-801	195	12	,	,	PUNCT
admet-801	195	13	it	it	PRON
admet-801	195	14	is	be	AUX
admet-801	195	15	important	important	ADJ
admet-801	195	16	to	to	PART
admet-801	195	17	take	take	VERB
admet-801	195	18	advantage	advantage	NOUN
admet-801	195	19	of	of	ADP
admet-801	195	20	usp	usp	NOUN
admet-801	195	21	apparatus	apparatus	NOUN
admet-801	195	22	4	4	NUM
admet-801	195	23	for	for	ADP
admet-801	195	24	the	the	DET
admet-801	195	25	evaluation	evaluation	NOUN
admet-801	195	26	of	of	ADP
admet-801	195	27	furosemide	furosemide	ADJ
admet-801	195	28	tablets	tablet	NOUN
admet-801	195	29	under	under	ADP
admet-801	195	30	the	the	DET
admet-801	195	31	hydrodynamic	hydrodynamic	ADJ
admet-801	195	32	environment	environment	NOUN
admet-801	195	33	that	that	SCONJ
admet-801	195	34	this	this	DET
admet-801	195	35	equipment	equipment	NOUN
admet-801	195	36	generates	generate	VERB
admet-801	195	37	.	.	PUNCT
admet-801	196	1	all	all	DET
admet-801	196	2	information	information	NOUN
admet-801	196	3	collected	collect	VERB
admet-801	196	4	is	be	AUX
admet-801	196	5	important	important	ADJ
admet-801	196	6	to	to	PART
admet-801	196	7	reduce	reduce	VERB
admet-801	196	8	the	the	DET
admet-801	196	9	negative	negative	ADJ
admet-801	196	10	clinical	clinical	ADJ
admet-801	196	11	impact	impact	NOUN
admet-801	196	12	that	that	PRON
admet-801	196	13	this	this	DET
admet-801	196	14	class	class	NOUN
admet-801	196	15	iv	iv	NUM
admet-801	196	16	drug	drug	NOUN
admet-801	196	17	presents	present	NOUN
admet-801	196	18	.	.	PUNCT
admet-801	197	1	this	this	DET
admet-801	197	2	furosemide	furosemide	ADJ
admet-801	197	3	reference	reference	NOUN
admet-801	197	4	product	product	NOUN
admet-801	197	5	is	be	AUX
admet-801	197	6	the	the	DET
admet-801	197	7	comparative	comparative	ADJ
admet-801	197	8	formulation	formulation	NOUN
admet-801	197	9	for	for	ADP
admet-801	197	10	generic	generic	ADJ
admet-801	197	11	drug	drug	NOUN
admet-801	197	12	products	product	NOUN
admet-801	197	13	;	;	PUNCT
admet-801	197	14	thus	thus	ADV
admet-801	197	15	,	,	PUNCT
admet-801	197	16	it	it	PRON
admet-801	197	17	is	be	AUX
admet-801	197	18	important	important	ADJ
admet-801	197	19	to	to	PART
admet-801	197	20	understand	understand	VERB
admet-801	197	21	the	the	DET
admet-801	197	22	in	in	ADV
admet-801	197	23	vitro	vitro	X
admet-801	197	24	release	release	NOUN
admet-801	197	25	performance	performance	NOUN
admet-801	197	26	under	under	ADP
admet-801	197	27	all	all	DET
admet-801	197	28	possible	possible	ADJ
admet-801	197	29	schemes	scheme	NOUN
admet-801	197	30	for	for	ADP
admet-801	197	31	the	the	DET
admet-801	197	32	design	design	NOUN
admet-801	197	33	of	of	ADP
admet-801	197	34	better	well	ADJ
admet-801	197	35	commercial	commercial	ADJ
admet-801	197	36	formulations	formulation	NOUN
admet-801	197	37	.	.	PUNCT
admet-801	198	1	acknowledgements	acknowledgement	NOUN
admet-801	198	2	:	:	PUNCT
admet-801	198	3	authors	author	NOUN
admet-801	198	4	thanks	thank	NOUN
admet-801	198	5	to	to	AUX
admet-801	198	6	qfb	qfb	VERB
admet-801	198	7	alexander	alexander	PROPN
admet-801	198	8	domínguez	domínguez	PROPN
admet-801	198	9	reyes	reyes	PROPN
admet-801	198	10	for	for	ADP
admet-801	198	11	his	his	PRON
admet-801	198	12	technical	technical	ADJ
admet-801	198	13	assistance	assistance	NOUN
admet-801	198	14	.	.	PUNCT
admet-801	199	1	conflict	conflict	NOUN
admet-801	199	2	of	of	ADP
admet-801	199	3	interest	interest	NOUN
admet-801	199	4	:	:	PUNCT
admet-801	199	5	declared	declare	VERB
admet-801	199	6	none	none	NOUN
admet-801	199	7	admet	admet	PROPN
admet-801	199	8	&	&	CCONJ
admet-801	199	9	dmpk	dmpk	PROPN
admet-801	199	10	8(4	8(4	NOUN
admet-801	199	11	)	)	PUNCT
admet-801	199	12	(	(	PUNCT
admet-801	199	13	2020	2020	NUM
admet-801	199	14	)	)	PUNCT
admet-801	199	15	411	411	NUM
admet-801	199	16	-	-	SYM
admet-801	199	17	423	423	NUM
admet-801	199	18	in	in	ADP
admet-801	199	19	vitro	vitro	X
admet-801	199	20	release	release	NOUN
admet-801	199	21	studies	study	NOUN
admet-801	199	22	of	of	ADP
admet-801	199	23	furosemide	furosemide	ADJ
admet-801	199	24	doi	doi	NOUN
admet-801	199	25	:	:	PUNCT
admet-801	199	26	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	NOUN
admet-801	199	27	421	421	NUM
admet-801	199	28	references	reference	NOUN
admet-801	199	29	[	[	X
admet-801	199	30	1	1	NUM
admet-801	199	31	]	]	X
admet-801	199	32	h.s	h.s	PROPN
admet-801	199	33	.	.	PROPN
admet-801	199	34	abou	abou	PROPN
admet-801	199	35	-	-	PUNCT
admet-801	199	36	auda	auda	NOUN
admet-801	199	37	,	,	PUNCT
admet-801	199	38	m.j	m.j	PROPN
admet-801	199	39	.	.	PROPN
admet-801	199	40	al	al	PROPN
admet-801	199	41	-	-	PUNCT
admet-801	199	42	yamani	yamani	PROPN
admet-801	199	43	,	,	PUNCT
admet-801	199	44	a.m.	a.m.	PROPN
admet-801	199	45	morad	morad	PROPN
admet-801	199	46	,	,	PUNCT
admet-801	199	47	s.a	s.a	PROPN
admet-801	199	48	.	.	PROPN
admet-801	199	49	bawazir	bawazir	PROPN
admet-801	199	50	,	,	PUNCT
admet-801	199	51	s.z	s.z	PROPN
admet-801	199	52	.	.	PROPN
admet-801	199	53	khan	khan	PROPN
admet-801	199	54	,	,	PUNCT
admet-801	199	55	k.i	k.i	PROPN
admet-801	199	56	.	.	PUNCT
admet-801	200	1	al	al	PROPN
admet-801	200	2	-	-	PUNCT
admet-801	200	3	khamis	khamis	PROPN
admet-801	200	4	.	.	PUNCT
admet-801	201	1	highperformance	highperformance	NOUN
admet-801	201	2	liquid	liquid	ADJ
admet-801	201	3	chromatographic	chromatographic	ADJ
admet-801	201	4	determination	determination	NOUN
admet-801	201	5	of	of	ADP
admet-801	201	6	furosemide	furosemide	NOUN
admet-801	201	7	in	in	ADP
admet-801	201	8	plasma	plasma	NOUN
admet-801	201	9	and	and	CCONJ
admet-801	201	10	urine	urine	NOUN
admet-801	201	11	and	and	CCONJ
admet-801	201	12	its	its	PRON
admet-801	201	13	use	use	NOUN
admet-801	201	14	in	in	ADP
admet-801	201	15	bioavailability	bioavailability	NOUN
admet-801	201	16	studies	study	NOUN
admet-801	201	17	.	.	PUNCT
admet-801	202	1	journal	journal	PROPN
admet-801	202	2	of	of	ADP
admet-801	202	3	chromatography	chromatography	PROPN
admet-801	202	4	b	b	PROPN
admet-801	202	5	710	710	NUM
admet-801	202	6	(	(	PUNCT
admet-801	202	7	1998	1998	NUM
admet-801	202	8	)	)	PUNCT
admet-801	202	9	121	121	NUM
admet-801	202	10	-	-	SYM
admet-801	202	11	128	128	NUM
admet-801	202	12	.	.	PUNCT
admet-801	203	1	[	[	X
admet-801	203	2	2	2	NUM
admet-801	203	3	]	]	PUNCT
admet-801	203	4	a.	a.	NOUN
admet-801	203	5	berthod	berthod	NOUN
admet-801	203	6	.	.	PUNCT
admet-801	204	1	hydrophobicity	hydrophobicity	NOUN
admet-801	204	2	of	of	ADP
admet-801	204	3	ionizable	ionizable	ADJ
admet-801	204	4	compounds	compound	NOUN
admet-801	204	5	.	.	PUNCT
admet-801	205	1	a	a	DET
admet-801	205	2	theoretical	theoretical	ADJ
admet-801	205	3	study	study	NOUN
admet-801	205	4	and	and	CCONJ
admet-801	205	5	measurements	measurement	NOUN
admet-801	205	6	of	of	ADP
admet-801	205	7	diuretic	diuretic	ADJ
admet-801	205	8	octanol	octanol	NOUN
admet-801	205	9	-	-	PUNCT
admet-801	205	10	water	water	NOUN
admet-801	205	11	partition	partition	NOUN
admet-801	205	12	coefficients	coefficient	NOUN
admet-801	205	13	by	by	ADP
admet-801	205	14	countercurrent	countercurrent	NOUN
admet-801	205	15	chromatography	chromatography	NOUN
admet-801	205	16	.	.	PUNCT
admet-801	206	1	analytical	analytical	ADJ
admet-801	206	2	chemistry	chemistry	NOUN
admet-801	206	3	71	71	NUM
admet-801	206	4	(	(	PUNCT
admet-801	206	5	1999	1999	NUM
admet-801	206	6	)	)	PUNCT
admet-801	206	7	879	879	NUM
admet-801	206	8	-	-	SYM
admet-801	206	9	888	888	NUM
admet-801	206	10	.	.	PUNCT
admet-801	207	1	[	[	X
admet-801	207	2	3	3	X
admet-801	207	3	]	]	X
admet-801	207	4	g.e	g.e	PROPN
admet-801	207	5	.	.	PROPN
admet-801	207	6	granero	granero	PROPN
admet-801	207	7	,	,	PUNCT
admet-801	207	8	m.r	m.r	PROPN
admet-801	207	9	.	.	PROPN
admet-801	207	10	longhi	longhi	PROPN
admet-801	207	11	,	,	PUNCT
admet-801	207	12	m.j	m.j	PROPN
admet-801	207	13	.	.	PROPN
admet-801	207	14	mora	mora	PROPN
admet-801	207	15	,	,	PUNCT
admet-801	207	16	h.e	h.e	PROPN
admet-801	207	17	.	.	PROPN
admet-801	207	18	junginger	junginger	PROPN
admet-801	207	19	,	,	PUNCT
admet-801	207	20	k.k	k.k	PROPN
admet-801	207	21	.	.	PROPN
admet-801	207	22	midha	midha	PROPN
admet-801	207	23	,	,	PUNCT
admet-801	207	24	v.p	v.p	PROPN
admet-801	207	25	.	.	PROPN
admet-801	207	26	shah	shah	PROPN
admet-801	207	27	,	,	PUNCT
admet-801	207	28	s.	s.	PROPN
admet-801	207	29	stavchansky	stavchansky	PROPN
admet-801	207	30	,	,	PUNCT
admet-801	207	31	j.b	j.b	PROPN
admet-801	207	32	.	.	PROPN
admet-801	208	1	dressman	dressman	PROPN
admet-801	208	2	,	,	PUNCT
admet-801	208	3	d.m	d.m	PROPN
admet-801	208	4	.	.	PUNCT
admet-801	208	5	barends	barends	PROPN
admet-801	208	6	.	.	PUNCT
admet-801	209	1	biowaiver	biowaiver	PROPN
admet-801	209	2	monographs	monograph	NOUN
admet-801	209	3	for	for	ADP
admet-801	209	4	immediate	immediate	ADJ
admet-801	209	5	-	-	PUNCT
admet-801	209	6	release	release	NOUN
admet-801	209	7	solid	solid	ADJ
admet-801	209	8	oral	oral	ADJ
admet-801	209	9	dosage	dosage	NOUN
admet-801	209	10	forms	form	NOUN
admet-801	209	11	:	:	PUNCT
admet-801	209	12	furosemide	furosemide	ADJ
admet-801	209	13	.	.	PUNCT
admet-801	210	1	journal	journal	NOUN
admet-801	210	2	of	of	ADP
admet-801	210	3	pharmaceutical	pharmaceutical	PROPN
admet-801	210	4	sciences	science	NOUN
admet-801	210	5	99	99	NUM
admet-801	210	6	(	(	PUNCT
admet-801	210	7	2010	2010	NUM
admet-801	210	8	)	)	PUNCT
admet-801	210	9	2544	2544	NUM
admet-801	210	10	-	-	SYM
admet-801	210	11	2556	2556	NUM
admet-801	210	12	.	.	PUNCT
admet-801	211	1	[	[	X
admet-801	211	2	4	4	X
admet-801	211	3	]	]	X
admet-801	211	4	g.	g.	NOUN
admet-801	211	5	tambosi	tambosi	PROPN
admet-801	211	6	,	,	PUNCT
admet-801	211	7	p.f	p.f	PROPN
admet-801	211	8	.	.	PROPN
admet-801	211	9	coelho	coelho	PROPN
admet-801	211	10	,	,	PUNCT
admet-801	211	11	l.	l.	PROPN
admet-801	211	12	soares	soares	PROPN
admet-801	211	13	,	,	PUNCT
admet-801	211	14	i.c	i.c	PROPN
admet-801	211	15	.	.	PROPN
admet-801	211	16	schmücker	schmücker	PROPN
admet-801	211	17	lenschow	lenschow	PROPN
admet-801	211	18	,	,	PUNCT
admet-801	211	19	m.	m.	NOUN
admet-801	211	20	zétola	zétola	PROPN
admet-801	211	21	,	,	PUNCT
admet-801	211	22	h.k	h.k	PROPN
admet-801	211	23	.	.	PROPN
admet-801	211	24	stulzer	stulzer	PROPN
admet-801	211	25	,	,	PUNCT
admet-801	211	26	b.	b.	PROPN
admet-801	211	27	ramos	ramos	PROPN
admet-801	211	28	pezzini	pezzini	PROPN
admet-801	211	29	.	.	PUNCT
admet-801	212	1	challenges	challenge	NOUN
admet-801	212	2	to	to	PART
admet-801	212	3	improve	improve	VERB
admet-801	212	4	the	the	DET
admet-801	212	5	biopharmaceutical	biopharmaceutical	ADJ
admet-801	212	6	properties	property	NOUN
admet-801	212	7	of	of	ADP
admet-801	212	8	poorly	poorly	ADV
admet-801	212	9	water	water	NOUN
admet-801	212	10	-	-	PUNCT
admet-801	212	11	soluble	soluble	ADJ
admet-801	212	12	drugs	drug	NOUN
admet-801	212	13	and	and	CCONJ
admet-801	212	14	the	the	DET
admet-801	212	15	application	application	NOUN
admet-801	212	16	of	of	ADP
admet-801	212	17	the	the	DET
admet-801	212	18	solid	solid	ADJ
admet-801	212	19	dispersion	dispersion	NOUN
admet-801	212	20	technology	technology	NOUN
admet-801	212	21	.	.	PUNCT
admet-801	213	1	revista	revista	PROPN
admet-801	213	2	matéria	matéria	PROPN
admet-801	213	3	23	23	NUM
admet-801	213	4	(	(	PUNCT
admet-801	213	5	2018	2018	NUM
admet-801	213	6	)	)	PUNCT
admet-801	213	7	e-12224	e-12224	NOUN
admet-801	213	8	.	.	PUNCT
admet-801	214	1	[	[	X
admet-801	214	2	5	5	NUM
admet-801	214	3	]	]	PUNCT
admet-801	214	4	a.	a.	NOUN
admet-801	214	5	garcía	garcía	NOUN
admet-801	214	6	-	-	PUNCT
admet-801	214	7	arieta	arieta	NOUN
admet-801	214	8	.	.	PUNCT
admet-801	214	9	interactions	interaction	NOUN
admet-801	214	10	between	between	ADP
admet-801	214	11	active	active	ADJ
admet-801	214	12	pharmaceutical	pharmaceutical	ADJ
admet-801	214	13	ingredients	ingredient	NOUN
admet-801	214	14	and	and	CCONJ
admet-801	214	15	excipients	excipient	NOUN
admet-801	214	16	affecting	affect	VERB
admet-801	214	17	bioavailability	bioavailability	NOUN
admet-801	214	18	:	:	PUNCT
admet-801	214	19	impact	impact	NOUN
admet-801	214	20	on	on	ADP
admet-801	214	21	bioequivalence	bioequivalence	NOUN
admet-801	214	22	.	.	PUNCT
admet-801	215	1	european	european	PROPN
admet-801	215	2	journal	journal	PROPN
admet-801	215	3	of	of	ADP
admet-801	215	4	pharmaceutical	pharmaceutical	PROPN
admet-801	215	5	sciences	science	NOUN
admet-801	215	6	65	65	NUM
admet-801	215	7	(	(	PUNCT
admet-801	215	8	2014	2014	NUM
admet-801	215	9	)	)	PUNCT
admet-801	215	10	89	89	NUM
admet-801	215	11	-	-	SYM
admet-801	215	12	97	97	NUM
admet-801	215	13	.	.	PUNCT
admet-801	216	1	[	[	X
admet-801	216	2	6	6	NUM
admet-801	216	3	]	]	X
admet-801	216	4	r.	r.	PROPN
admet-801	216	5	ghadi	ghadi	PROPN
admet-801	216	6	,	,	PUNCT
admet-801	216	7	n.	n.	PROPN
admet-801	216	8	dand	dand	PROPN
admet-801	216	9	.	.	PUNCT
admet-801	216	10	bcs	bcs	NOUN
admet-801	216	11	class	class	NOUN
admet-801	216	12	iv	iv	NUM
admet-801	216	13	drugs	drug	NOUN
admet-801	216	14	:	:	PUNCT
admet-801	216	15	highly	highly	ADV
admet-801	216	16	notorious	notorious	ADJ
admet-801	216	17	candidates	candidate	NOUN
admet-801	216	18	for	for	ADP
admet-801	216	19	formulation	formulation	NOUN
admet-801	216	20	development	development	NOUN
admet-801	216	21	.	.	PUNCT
admet-801	217	1	journal	journal	PROPN
admet-801	217	2	of	of	ADP
admet-801	217	3	controlled	control	VERB
admet-801	217	4	release	release	NOUN
admet-801	217	5	248	248	NUM
admet-801	217	6	(	(	PUNCT
admet-801	217	7	2017	2017	NUM
admet-801	217	8	)	)	PUNCT
admet-801	217	9	71	71	NUM
admet-801	217	10	-	-	SYM
admet-801	217	11	95	95	NUM
admet-801	217	12	.	.	PUNCT
admet-801	218	1	[	[	X
admet-801	218	2	7	7	X
admet-801	218	3	]	]	X
admet-801	218	4	m.r	m.r	PROPN
admet-801	218	5	.	.	PROPN
admet-801	218	6	kelly	kelly	PROPN
admet-801	218	7	,	,	PUNCT
admet-801	218	8	r.e	r.e	PROPN
admet-801	218	9	.	.	PROPN
admet-801	218	10	cutler	cutler	PROPN
admet-801	218	11	,	,	PUNCT
admet-801	218	12	a.w	a.w	PROPN
admet-801	218	13	.	.	PROPN
admet-801	218	14	forrey	forrey	PROPN
admet-801	218	15	,	,	PUNCT
admet-801	218	16	b.m	b.m	PROPN
admet-801	218	17	.	.	PROPN
admet-801	218	18	kimpel	kimpel	PROPN
admet-801	218	19	.	.	PUNCT
admet-801	219	1	pharmacokinetics	pharmacokinetic	NOUN
admet-801	219	2	of	of	ADP
admet-801	219	3	orally	orally	ADV
admet-801	219	4	administered	administer	VERB
admet-801	219	5	furosemide	furosemide	ADV
admet-801	219	6	.	.	PUNCT
admet-801	220	1	clinical	clinical	ADJ
admet-801	220	2	pharmacology	pharmacology	NOUN
admet-801	220	3	and	and	CCONJ
admet-801	220	4	therapeutics	therapeutic	NOUN
admet-801	220	5	15	15	NUM
admet-801	220	6	(	(	PUNCT
admet-801	220	7	1973	1973	NUM
admet-801	220	8	)	)	PUNCT
admet-801	220	9	178˗186	178˗186	NUM
admet-801	220	10	.	.	PUNCT
admet-801	221	1	[	[	X
admet-801	221	2	8	8	NUM
admet-801	221	3	]	]	X
admet-801	221	4	s.	s.	PROPN
admet-801	221	5	sweetman	sweetman	PROPN
admet-801	221	6	.	.	PUNCT
admet-801	222	1	martindale	martindale	PROPN
admet-801	222	2	:	:	PUNCT
admet-801	222	3	the	the	DET
admet-801	222	4	complete	complete	ADJ
admet-801	222	5	drug	drug	NOUN
admet-801	222	6	reference	reference	NOUN
admet-801	222	7	.	.	PUNCT
admet-801	223	1	(	(	PUNCT
admet-801	223	2	electronic	electronic	ADJ
admet-801	223	3	version	version	NOUN
admet-801	223	4	)	)	PUNCT
admet-801	223	5	pharmaceutical	pharmaceutical	NOUN
admet-801	223	6	press	press	NOUN
admet-801	223	7	.	.	PUNCT
admet-801	224	1	thomson	thomson	PROPN
admet-801	224	2	/	/	SYM
admet-801	224	3	micromedex	micromedex	PROPN
admet-801	224	4	,	,	PUNCT
admet-801	224	5	london	london	PROPN
admet-801	224	6	,	,	PUNCT
admet-801	224	7	uk	uk	PROPN
admet-801	224	8	/	/	SYM
admet-801	224	9	greenwood	greenwood	PROPN
admet-801	224	10	village	village	PROPN
admet-801	224	11	,	,	PUNCT
admet-801	224	12	colorado	colorado	PROPN
admet-801	224	13	.	.	PUNCT
admet-801	224	14	2009	2009	NUM
admet-801	224	15	.	.	PUNCT
admet-801	225	1	[	[	X
admet-801	225	2	9	9	NUM
admet-801	225	3	]	]	PUNCT
admet-801	225	4	a.	a.	NOUN
admet-801	225	5	grahnén	grahnén	PROPN
admet-801	225	6	,	,	PUNCT
admet-801	225	7	m.	m.	NOUN
admet-801	225	8	hammarlund	hammarlund	PROPN
admet-801	225	9	,	,	PUNCT
admet-801	225	10	t.	t.	PROPN
admet-801	225	11	lundqvist	lundqvist	PROPN
admet-801	225	12	.	.	PUNCT
admet-801	226	1	implications	implication	NOUN
admet-801	226	2	of	of	ADP
admet-801	226	3	intraindividual	intraindividual	ADJ
admet-801	226	4	variability	variability	NOUN
admet-801	226	5	in	in	ADP
admet-801	226	6	bioavailability	bioavailability	NOUN
admet-801	226	7	studies	study	NOUN
admet-801	226	8	of	of	ADP
admet-801	226	9	furosemide	furosemide	NOUN
admet-801	226	10	.	.	PUNCT
admet-801	227	1	european	european	ADJ
admet-801	227	2	journal	journal	PROPN
admet-801	227	3	of	of	ADP
admet-801	227	4	clinical	clinical	ADJ
admet-801	227	5	pharmacology	pharmacology	NOUN
admet-801	227	6	27	27	NUM
admet-801	227	7	(	(	PUNCT
admet-801	227	8	1984	1984	NUM
admet-801	227	9	)	)	PUNCT
admet-801	227	10	595˗602	595˗602	NUM
admet-801	227	11	.	.	PUNCT
admet-801	228	1	[	[	X
admet-801	228	2	10	10	NUM
admet-801	228	3	]	]	X
admet-801	228	4	s.	s.	PROPN
admet-801	228	5	kaojarern	kaojarern	PROPN
admet-801	228	6	,	,	PUNCT
admet-801	228	7	o.	o.	PROPN
admet-801	228	8	poobrasert	poobrasert	PROPN
admet-801	228	9	,	,	PUNCT
admet-801	228	10	a.	a.	NOUN
admet-801	228	11	utiswannakul	utiswannakul	NOUN
admet-801	228	12	,	,	PUNCT
admet-801	228	13	u.	u.	PROPN
admet-801	228	14	kositchaiwat	kositchaiwat	PROPN
admet-801	228	15	.	.	PUNCT
admet-801	229	1	bioavailability	bioavailability	NOUN
admet-801	229	2	and	and	CCONJ
admet-801	229	3	pharmacokinetics	pharmacokinetic	NOUN
admet-801	229	4	of	of	ADP
admet-801	229	5	furosemide	furosemide	ADV
admet-801	229	6	marketed	market	VERB
admet-801	229	7	in	in	ADP
admet-801	229	8	thailand	thailand	PROPN
admet-801	229	9	.	.	PUNCT
admet-801	230	1	journal	journal	PROPN
admet-801	230	2	of	of	ADP
admet-801	230	3	the	the	DET
admet-801	230	4	medical	medical	ADJ
admet-801	230	5	association	association	PROPN
admet-801	230	6	of	of	ADP
admet-801	230	7	thailand	thailand	PROPN
admet-801	230	8	73	73	NUM
admet-801	230	9	(	(	PUNCT
admet-801	230	10	1990	1990	NUM
admet-801	230	11	)	)	PUNCT
admet-801	231	1	191˗197	191˗197	NUM
admet-801	231	2	.	.	PUNCT
admet-801	232	1	[	[	X
admet-801	232	2	11	11	NUM
admet-801	232	3	]	]	X
admet-801	232	4	w.	w.	PROPN
admet-801	232	5	stüber	stüber	PROPN
admet-801	232	6	,	,	PUNCT
admet-801	232	7	e.	e.	PROPN
admet-801	232	8	mutschler	mutschler	PROPN
admet-801	232	9	,	,	PUNCT
admet-801	232	10	d.	d.	PROPN
admet-801	232	11	steinbach	steinbach	PROPN
admet-801	232	12	.	.	PUNCT
admet-801	233	1	the	the	DET
admet-801	233	2	pharmaceutical	pharmaceutical	ADJ
admet-801	233	3	and	and	CCONJ
admet-801	233	4	biological	biological	ADJ
admet-801	233	5	availability	availability	NOUN
admet-801	233	6	of	of	ADP
admet-801	233	7	commercial	commercial	ADJ
admet-801	233	8	preparations	preparation	NOUN
admet-801	233	9	of	of	ADP
admet-801	233	10	furosemide	furosemide	NOUN
admet-801	233	11	.	.	PUNCT
admet-801	234	1	arzneimittelforschung	arzneimittelforschung	PROPN
admet-801	234	2	drug	drug	NOUN
admet-801	234	3	research	research	NOUN
admet-801	234	4	32	32	NUM
admet-801	234	5	(	(	PUNCT
admet-801	234	6	1982	1982	NUM
admet-801	234	7	)	)	PUNCT
admet-801	234	8	693	693	NUM
admet-801	234	9	-	-	SYM
admet-801	234	10	697	697	NUM
admet-801	234	11	.	.	PUNCT
admet-801	235	1	[	[	X
admet-801	235	2	12	12	NUM
admet-801	235	3	]	]	X
admet-801	235	4	united	united	PROPN
admet-801	235	5	states	states	PROPN
admet-801	235	6	pharmacopeia	pharmacopeia	PROPN
admet-801	235	7	and	and	CCONJ
admet-801	235	8	national	national	ADJ
admet-801	235	9	formulary	formulary	NOUN
admet-801	235	10	usp	usp	PROPN
admet-801	235	11	42	42	NUM
admet-801	235	12	-	-	PUNCT
admet-801	235	13	nf	nf	NOUN
admet-801	235	14	37	37	NUM
admet-801	235	15	;	;	PUNCT
admet-801	235	16	united	united	PROPN
admet-801	235	17	states	states	PROPN
admet-801	235	18	pharmacopeial	pharmacopeial	ADJ
admet-801	235	19	convention	convention	PROPN
admet-801	235	20	,	,	PUNCT
admet-801	235	21	inc	inc	PROPN
admet-801	235	22	:	:	PUNCT
admet-801	235	23	rockville	rockville	PROPN
admet-801	235	24	md	md	PROPN
admet-801	235	25	;	;	PUNCT
admet-801	235	26	2019	2019	NUM
admet-801	235	27	.	.	PUNCT
admet-801	236	1	[	[	X
admet-801	236	2	13	13	NUM
admet-801	236	3	]	]	PUNCT
admet-801	236	4	m.	m.	NOUN
admet-801	236	5	morihara	morihara	PROPN
admet-801	236	6	,	,	PUNCT
admet-801	236	7	n.	n.	PROPN
admet-801	236	8	aoyagi	aoyagi	PROPN
admet-801	236	9	,	,	PUNCT
admet-801	236	10	n.	n.	PROPN
admet-801	236	11	kaniwa	kaniwa	PROPN
admet-801	236	12	,	,	PUNCT
admet-801	236	13	n.	n.	PROPN
admet-801	236	14	katori	katori	PROPN
admet-801	236	15	,	,	PUNCT
admet-801	236	16	s.	s.	PROPN
admet-801	236	17	kojim	kojim	PROPN
admet-801	236	18	.	.	PUNCT
admet-801	237	1	hydrodynamic	hydrodynamic	ADJ
admet-801	237	2	flows	flow	NOUN
admet-801	237	3	around	around	ADP
admet-801	237	4	tablets	tablet	NOUN
admet-801	237	5	in	in	ADP
admet-801	237	6	different	different	ADJ
admet-801	237	7	pharmacopeial	pharmacopeial	ADJ
admet-801	237	8	dissolution	dissolution	NOUN
admet-801	237	9	tests	test	NOUN
admet-801	237	10	.	.	PUNCT
admet-801	238	1	drug	drug	NOUN
admet-801	238	2	development	development	NOUN
admet-801	238	3	and	and	CCONJ
admet-801	238	4	industrial	industrial	ADJ
admet-801	238	5	pharmacy	pharmacy	NOUN
admet-801	238	6	28	28	NUM
admet-801	238	7	(	(	PUNCT
admet-801	238	8	2002	2002	NUM
admet-801	238	9	)	)	PUNCT
admet-801	238	10	655	655	NUM
admet-801	238	11	-	-	SYM
admet-801	238	12	662	662	NUM
admet-801	238	13	.	.	PUNCT
admet-801	239	1	[	[	X
admet-801	239	2	14	14	NUM
admet-801	239	3	]	]	PUNCT
admet-801	239	4	k.	k.	PROPN
admet-801	239	5	greco	greco	PROPN
admet-801	239	6	,	,	PUNCT
admet-801	239	7	t.l	t.l	PROPN
admet-801	239	8	.	.	PROPN
admet-801	239	9	bergman	bergman	PROPN
admet-801	239	10	,	,	PUNCT
admet-801	239	11	r.	r.	PROPN
admet-801	239	12	bogner	bogner	PROPN
admet-801	239	13	.	.	PUNCT
admet-801	240	1	design	design	NOUN
admet-801	240	2	and	and	CCONJ
admet-801	240	3	characterization	characterization	NOUN
admet-801	240	4	of	of	ADP
admet-801	240	5	laminar	laminar	ADJ
admet-801	240	6	flow	flow	NOUN
admet-801	240	7	-	-	PUNCT
admet-801	240	8	through	through	ADP
admet-801	240	9	dissolution	dissolution	NOUN
admet-801	240	10	apparatus	apparatus	NOUN
admet-801	240	11	:	:	PUNCT
admet-801	240	12	comparison	comparison	NOUN
admet-801	240	13	of	of	ADP
admet-801	240	14	hydrodynamic	hydrodynamic	ADJ
admet-801	240	15	conditions	condition	NOUN
admet-801	240	16	to	to	ADP
admet-801	240	17	those	those	PRON
admet-801	240	18	of	of	ADP
admet-801	240	19	common	common	ADJ
admet-801	240	20	dissolution	dissolution	NOUN
admet-801	240	21	techniques	technique	NOUN
admet-801	240	22	.	.	PUNCT
admet-801	241	1	pharmaceutical	pharmaceutical	NOUN
admet-801	241	2	development	development	NOUN
admet-801	241	3	and	and	CCONJ
admet-801	241	4	technology	technology	NOUN
admet-801	241	5	16	16	NUM
admet-801	241	6	(	(	PUNCT
admet-801	241	7	2011	2011	NUM
admet-801	241	8	)	)	PUNCT
admet-801	241	9	75	75	NUM
admet-801	241	10	-	-	SYM
admet-801	241	11	87	87	NUM
admet-801	241	12	.	.	PUNCT
admet-801	242	1	[	[	X
admet-801	242	2	15	15	NUM
admet-801	242	3	]	]	X
admet-801	242	4	v.	v.	ADP
admet-801	242	5	todaro	todaro	NOUN
admet-801	242	6	,	,	PUNCT
admet-801	242	7	t.	t.	NOUN
admet-801	242	8	persoons	persoon	NOUN
admet-801	242	9	,	,	PUNCT
admet-801	242	10	g.	g.	PROPN
admet-801	242	11	grove	grove	PROPN
admet-801	242	12	,	,	PUNCT
admet-801	242	13	m.a	m.a	PROPN
admet-801	242	14	.	.	PROPN
admet-801	242	15	healy	healy	PROPN
admet-801	242	16	,	,	PUNCT
admet-801	242	17	d.m	d.m	PROPN
admet-801	242	18	.	.	PUNCT
admet-801	242	19	d’arcy	d’arcy	PROPN
admet-801	242	20	.	.	PUNCT
admet-801	243	1	characterization	characterization	NOUN
admet-801	243	2	and	and	CCONJ
admet-801	243	3	simulation	simulation	NOUN
admet-801	243	4	of	of	ADP
admet-801	243	5	hydrodynamics	hydrodynamic	NOUN
admet-801	243	6	in	in	ADP
admet-801	243	7	the	the	DET
admet-801	243	8	paddle	paddle	NOUN
admet-801	243	9	,	,	PUNCT
admet-801	243	10	basket	basket	NOUN
admet-801	243	11	and	and	CCONJ
admet-801	243	12	flow	flow	NOUN
admet-801	243	13	-	-	PUNCT
admet-801	243	14	through	through	ADP
admet-801	243	15	dissolution	dissolution	NOUN
admet-801	243	16	testing	testing	NOUN
admet-801	243	17	apparatuses	apparatuse	VERB
admet-801	243	18	a	a	DET
admet-801	243	19	review	review	NOUN
admet-801	243	20	.	.	PUNCT
admet-801	244	1	dissolution	dissolution	PROPN
admet-801	244	2	technologies	technology	NOUN
admet-801	244	3	24	24	NUM
admet-801	244	4	(	(	PUNCT
admet-801	244	5	2017	2017	NUM
admet-801	244	6	)	)	PUNCT
admet-801	244	7	24	24	NUM
admet-801	244	8	-	-	SYM
admet-801	244	9	36	36	NUM
admet-801	244	10	.	.	PUNCT
admet-801	245	1	[	[	X
admet-801	245	2	16	16	NUM
admet-801	245	3	]	]	X
admet-801	245	4	s.n	s.n	PROPN
admet-801	245	5	.	.	PROPN
admet-801	245	6	bhattachar	bhattachar	PROPN
admet-801	245	7	,	,	PUNCT
admet-801	245	8	j.a	j.a	PROPN
admet-801	245	9	.	.	PROPN
admet-801	245	10	wesley	wesley	PROPN
admet-801	245	11	,	,	PUNCT
admet-801	245	12	a.	a.	PROPN
admet-801	245	13	fioritto	fioritto	PROPN
admet-801	245	14	,	,	PUNCT
admet-801	245	15	p.j	p.j	PROPN
admet-801	245	16	.	.	PROPN
admet-801	245	17	martin	martin	PROPN
admet-801	245	18	,	,	PUNCT
admet-801	245	19	s.r	s.r	PROPN
admet-801	245	20	.	.	PROPN
admet-801	245	21	babu	babu	PROPN
admet-801	245	22	.	.	PUNCT
admet-801	246	1	dissolution	dissolution	PROPN
admet-801	246	2	testing	testing	NOUN
admet-801	246	3	of	of	ADP
admet-801	246	4	a	a	DET
admet-801	246	5	poorly	poorly	ADV
admet-801	246	6	soluble	soluble	ADJ
admet-801	246	7	compound	compound	NOUN
admet-801	246	8	using	use	VERB
admet-801	246	9	the	the	DET
admet-801	246	10	flow	flow	NOUN
admet-801	246	11	-	-	PUNCT
admet-801	246	12	through	through	ADP
admet-801	246	13	cell	cell	NOUN
admet-801	246	14	dissolution	dissolution	NOUN
admet-801	246	15	apparatus	apparatus	NOUN
admet-801	246	16	.	.	PUNCT
admet-801	247	1	international	international	ADJ
admet-801	247	2	journal	journal	PROPN
admet-801	247	3	of	of	ADP
admet-801	247	4	pharmaceutics	pharmaceutic	NOUN
admet-801	247	5	236	236	NUM
admet-801	247	6	(	(	PUNCT
admet-801	247	7	2002	2002	NUM
admet-801	247	8	)	)	PUNCT
admet-801	247	9	135	135	NUM
admet-801	247	10	-	-	SYM
admet-801	247	11	143	143	NUM
admet-801	247	12	.	.	PUNCT
admet-801	248	1	[	[	X
admet-801	248	2	17	17	NUM
admet-801	248	3	]	]	X
admet-801	248	4	e.	e.	PROPN
admet-801	248	5	beyssac	beyssac	PROPN
admet-801	248	6	,	,	PUNCT
admet-801	248	7	j.	j.	PROPN
admet-801	248	8	lavigne	lavigne	PROPN
admet-801	248	9	.	.	PUNCT
admet-801	249	1	dissolution	dissolution	PROPN
admet-801	249	2	study	study	NOUN
admet-801	249	3	of	of	ADP
admet-801	249	4	active	active	ADJ
admet-801	249	5	pharmaceutical	pharmaceutical	ADJ
admet-801	249	6	ingredients	ingredient	NOUN
admet-801	249	7	using	use	VERB
admet-801	249	8	the	the	DET
admet-801	249	9	flow	flow	NOUN
admet-801	249	10	through	through	ADP
admet-801	249	11	apparatus	apparatus	NOUN
admet-801	249	12	usp	usp	PROPN
admet-801	249	13	4	4	NUM
admet-801	249	14	.	.	PUNCT
admet-801	250	1	dissolution	dissolution	PROPN
admet-801	250	2	technologies	technology	NOUN
admet-801	250	3	12	12	NUM
admet-801	250	4	(	(	PUNCT
admet-801	250	5	2005	2005	NUM
admet-801	250	6	)	)	PUNCT
admet-801	250	7	23	23	NUM
admet-801	250	8	-	-	SYM
admet-801	250	9	25	25	NUM
admet-801	250	10	.	.	PUNCT
admet-801	251	1	[	[	X
admet-801	251	2	18	18	NUM
admet-801	251	3	]	]	X
admet-801	251	4	n.	n.	NOUN
admet-801	251	5	fotaki	fotaki	PROPN
admet-801	251	6	,	,	PUNCT
admet-801	251	7	c.	c.	PROPN
admet-801	251	8	reppas	reppas	PROPN
admet-801	251	9	.	.	PUNCT
admet-801	252	1	the	the	DET
admet-801	252	2	flow	flow	NOUN
admet-801	252	3	through	through	ADP
admet-801	252	4	cell	cell	NOUN
admet-801	252	5	methodology	methodology	NOUN
admet-801	252	6	in	in	ADP
admet-801	252	7	the	the	DET
admet-801	252	8	evaluation	evaluation	NOUN
admet-801	252	9	of	of	ADP
admet-801	252	10	intralumenal	intralumenal	ADJ
admet-801	252	11	drug	drug	NOUN
admet-801	252	12	release	release	NOUN
admet-801	252	13	characteristics	characteristic	NOUN
admet-801	252	14	.	.	PUNCT
admet-801	253	1	dissolution	dissolution	PROPN
admet-801	253	2	technologies	technology	NOUN
admet-801	253	3	12	12	NUM
admet-801	253	4	(	(	PUNCT
admet-801	253	5	2005	2005	NUM
admet-801	253	6	)	)	PUNCT
admet-801	253	7	17	17	NUM
admet-801	253	8	-	-	SYM
admet-801	253	9	21	21	NUM
admet-801	253	10	.	.	PUNCT
admet-801	254	1	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	PROPN
admet-801	254	2	medina	medina	PROPN
admet-801	254	3	-	-	PUNCT
admet-801	254	4	lópez	lópez	PROPN
admet-801	254	5	et	et	PROPN
admet-801	254	6	al	al	PROPN
admet-801	254	7	.	.	PROPN
admet-801	254	8	admet	admet	PROPN
admet-801	254	9	&	&	CCONJ
admet-801	254	10	dmpk	dmpk	PROPN
admet-801	254	11	8(4	8(4	NOUN
admet-801	254	12	)	)	PUNCT
admet-801	254	13	(	(	PUNCT
admet-801	254	14	2020	2020	NUM
admet-801	254	15	)	)	PUNCT
admet-801	254	16	411	411	NUM
admet-801	254	17	-	-	SYM
admet-801	254	18	423	423	NUM
admet-801	254	19	422	422	NUM
admet-801	254	20	[	[	X
admet-801	254	21	19	19	NUM
admet-801	254	22	]	]	PUNCT
admet-801	254	23	j.	j.	PROPN
admet-801	254	24	jinno	jinno	PROPN
admet-801	254	25	,	,	PUNCT
admet-801	254	26	n.	n.	PROPN
admet-801	254	27	kamada	kamada	PROPN
admet-801	254	28	,	,	PUNCT
admet-801	254	29	m.	m.	PROPN
admet-801	254	30	miyake	miyake	PROPN
admet-801	254	31	,	,	PUNCT
admet-801	254	32	k.	k.	PROPN
admet-801	254	33	yamada	yamada	PROPN
admet-801	254	34	,	,	PUNCT
admet-801	254	35	t.	t.	PROPN
admet-801	254	36	mukai	mukai	PROPN
admet-801	254	37	,	,	PUNCT
admet-801	254	38	m.	m.	NOUN
admet-801	254	39	odomi	odomi	PROPN
admet-801	254	40	,	,	PUNCT
admet-801	254	41	h.	h.	PROPN
admet-801	254	42	toguchi	toguchi	PROPN
admet-801	254	43	,	,	PUNCT
admet-801	254	44	g.g	g.g	PROPN
admet-801	254	45	.	.	PROPN
admet-801	254	46	liversidge	liversidge	PROPN
admet-801	254	47	,	,	PUNCT
admet-801	254	48	k.	k.	PROPN
admet-801	254	49	higaki	higaki	PROPN
admet-801	254	50	,	,	PUNCT
admet-801	254	51	t.	t.	PROPN
admet-801	254	52	kimura	kimura	NOUN
admet-801	254	53	.	.	PUNCT
admet-801	255	1	in	in	ADP
admet-801	255	2	vitro	vitro	NOUN
admet-801	255	3	-	-	PUNCT
admet-801	255	4	in	in	ADP
admet-801	255	5	vivo	vivo	NOUN
admet-801	255	6	correlation	correlation	NOUN
admet-801	255	7	for	for	ADP
admet-801	255	8	wet	wet	NOUN
admet-801	255	9	-	-	PUNCT
admet-801	255	10	milled	mill	VERB
admet-801	255	11	tablet	tablet	NOUN
admet-801	255	12	of	of	ADP
admet-801	255	13	poorly	poorly	ADV
admet-801	255	14	water	water	NOUN
admet-801	255	15	-	-	PUNCT
admet-801	255	16	soluble	soluble	ADJ
admet-801	255	17	cilostazol	cilostazol	ADJ
admet-801	255	18	.	.	PUNCT
admet-801	256	1	journal	journal	PROPN
admet-801	256	2	of	of	ADP
admet-801	256	3	controlled	control	VERB
admet-801	256	4	release	release	NOUN
admet-801	256	5	130	130	NUM
admet-801	256	6	(	(	PUNCT
admet-801	256	7	2008	2008	NUM
admet-801	256	8	)	)	PUNCT
admet-801	256	9	29	29	NUM
admet-801	256	10	-	-	SYM
admet-801	256	11	37	37	NUM
admet-801	256	12	.	.	PUNCT
admet-801	257	1	[	[	X
admet-801	257	2	20	20	NUM
admet-801	257	3	]	]	PUNCT
admet-801	257	4	e.	e.	PROPN
admet-801	257	5	jantratid	jantratid	PROPN
admet-801	257	6	,	,	PUNCT
admet-801	257	7	v.	v.	PROPN
admet-801	257	8	de	de	PROPN
admet-801	257	9	maio	maio	PROPN
admet-801	257	10	,	,	PUNCT
admet-801	257	11	e.	e.	PROPN
admet-801	257	12	ronda	ronda	PROPN
admet-801	257	13	,	,	PUNCT
admet-801	257	14	v.	v.	PROPN
admet-801	257	15	mattavelli	mattavelli	PROPN
admet-801	257	16	,	,	PUNCT
admet-801	257	17	m.	m.	NOUN
admet-801	257	18	vertzoni	vertzoni	PROPN
admet-801	257	19	,	,	PUNCT
admet-801	257	20	j.b	j.b	PROPN
admet-801	257	21	.	.	PROPN
admet-801	257	22	dressman	dressman	PROPN
admet-801	257	23	.	.	PUNCT
admet-801	258	1	application	application	NOUN
admet-801	258	2	of	of	ADP
admet-801	258	3	biorelevant	biorelevant	ADJ
admet-801	258	4	dissolution	dissolution	NOUN
admet-801	258	5	tests	test	NOUN
admet-801	258	6	to	to	ADP
admet-801	258	7	the	the	DET
admet-801	258	8	prediction	prediction	NOUN
admet-801	258	9	of	of	ADP
admet-801	258	10	in	in	ADP
admet-801	258	11	vivo	vivo	ADJ
admet-801	258	12	performance	performance	NOUN
admet-801	258	13	of	of	ADP
admet-801	258	14	diclofenac	diclofenac	ADJ
admet-801	258	15	sodium	sodium	NOUN
admet-801	258	16	from	from	ADP
admet-801	258	17	an	an	DET
admet-801	258	18	oral	oral	ADJ
admet-801	258	19	modified	modify	VERB
admet-801	258	20	-	-	PUNCT
admet-801	258	21	release	release	NOUN
admet-801	258	22	pellet	pellet	NOUN
admet-801	258	23	dosage	dosage	NOUN
admet-801	258	24	form	form	NOUN
admet-801	258	25	.	.	PUNCT
admet-801	259	1	european	european	ADJ
admet-801	259	2	journal	journal	PROPN
admet-801	259	3	of	of	ADP
admet-801	259	4	pharmaceutical	pharmaceutical	PROPN
admet-801	259	5	sciences	science	NOUN
admet-801	259	6	37	37	NUM
admet-801	259	7	(	(	PUNCT
admet-801	259	8	2009	2009	NUM
admet-801	259	9	)	)	PUNCT
admet-801	259	10	434	434	NUM
admet-801	259	11	-	-	SYM
admet-801	259	12	441	441	NUM
admet-801	259	13	.	.	PUNCT
admet-801	260	1	[	[	X
admet-801	260	2	21	21	NUM
admet-801	260	3	]	]	PUNCT
admet-801	260	4	listado	listado	X
admet-801	260	5	actualizado	actualizado	X
admet-801	260	6	de	de	X
admet-801	260	7	medicamentos	medicamentos	X
admet-801	260	8	de	de	X
admet-801	260	9	referencia	referencia	PROPN
admet-801	260	10	2019/01	2019/01	NUM
admet-801	260	11	,	,	PUNCT
admet-801	260	12	https://www.gob.mx/cms/uploads/attachment/file/441323/listado_de_medicamentos_de_referencia_.pdf	https://www.gob.mx/cms/uploads/attachment/file/441323/listado_de_medicamentos_de_referencia_.pdf	PROPN
admet-801	260	13	,	,	PUNCT
admet-801	260	14	accessed	access	VERB
admet-801	260	15	on	on	ADP
admet-801	260	16	04	04	NUM
admet-801	260	17	march	march	NOUN
admet-801	260	18	2020	2020	NUM
admet-801	260	19	.	.	PUNCT
admet-801	261	1	[	[	X
admet-801	261	2	22	22	NUM
admet-801	261	3	]	]	X
admet-801	261	4	y.	y.	PROPN
admet-801	261	5	tanigawara	tanigawara	PROPN
admet-801	261	6	,	,	PUNCT
admet-801	261	7	k.	k.	PROPN
admet-801	261	8	yamaoka	yamaoka	PROPN
admet-801	261	9	,	,	PUNCT
admet-801	261	10	t.	t.	PROPN
admet-801	261	11	nakagawa	nakagawa	PROPN
admet-801	261	12	,	,	PUNCT
admet-801	261	13	t.	t.	PROPN
admet-801	261	14	unzo	unzo	PROPN
admet-801	261	15	.	.	PUNCT
admet-801	262	1	new	new	ADJ
admet-801	262	2	method	method	NOUN
admet-801	262	3	for	for	ADP
admet-801	262	4	the	the	DET
admet-801	262	5	evaluation	evaluation	NOUN
admet-801	262	6	of	of	ADP
admet-801	262	7	in	in	ADP
admet-801	262	8	vitro	vitro	X
admet-801	262	9	dissolution	dissolution	ADJ
admet-801	262	10	time	time	NOUN
admet-801	262	11	and	and	CCONJ
admet-801	262	12	disintegration	disintegration	NOUN
admet-801	262	13	time	time	NOUN
admet-801	262	14	.	.	PUNCT
admet-801	263	1	chemical	chemical	NOUN
admet-801	263	2	and	and	CCONJ
admet-801	263	3	pharmaceutical	pharmaceutical	ADJ
admet-801	263	4	bulletin	bulletin	NOUN
admet-801	263	5	30	30	NUM
admet-801	263	6	(	(	PUNCT
admet-801	263	7	1982	1982	NUM
admet-801	263	8	)	)	PUNCT
admet-801	263	9	10881090	10881090	NUM
admet-801	263	10	.	.	PUNCT
admet-801	264	1	[	[	X
admet-801	264	2	23	23	NUM
admet-801	264	3	]	]	X
admet-801	264	4	p.s	p.s	PROPN
admet-801	264	5	.	.	PROPN
admet-801	264	6	collier	collier	PROPN
admet-801	264	7	.	.	PUNCT
admet-801	265	1	the	the	DET
admet-801	265	2	interpretation	interpretation	NOUN
admet-801	265	3	of	of	ADP
admet-801	265	4	in	in	ADP
admet-801	265	5	vivo	vivo	NOUN
admet-801	265	6	mean	mean	NOUN
admet-801	265	7	dissolution	dissolution	PROPN
admet-801	265	8	time	time	NOUN
admet-801	265	9	data	data	PROPN
admet-801	265	10	.	.	PUNCT
admet-801	266	1	in	in	ADP
admet-801	266	2	:	:	PUNCT
admet-801	266	3	benet	benet	PROPN
admet-801	266	4	l.z	l.z	PROPN
admet-801	266	5	.	.	PROPN
admet-801	266	6	,	,	PUNCT
admet-801	266	7	levy	levy	NOUN
admet-801	266	8	g.	g.	PROPN
admet-801	266	9	,	,	PUNCT
admet-801	266	10	ferraiolo	ferraiolo	PROPN
admet-801	266	11	b.l	b.l	PROPN
admet-801	266	12	.	.	PROPN
admet-801	266	13	(	(	PUNCT
admet-801	266	14	eds	ed	NOUN
admet-801	266	15	)	)	PUNCT
admet-801	266	16	pharmacokinetics	pharmacokinetic	NOUN
admet-801	266	17	.	.	PUNCT
admet-801	266	18	springer	springer	NOUN
admet-801	266	19	-	-	PUNCT
admet-801	266	20	verlang	verlang	PROPN
admet-801	266	21	.	.	PROPN
admet-801	266	22	boston	boston	PROPN
admet-801	266	23	,	,	PUNCT
admet-801	266	24	usa	usa	PROPN
admet-801	266	25	.	.	PROPN
admet-801	266	26	1984	1984	NUM
admet-801	266	27	.	.	PUNCT
admet-801	267	1	[	[	X
admet-801	267	2	24	24	NUM
admet-801	267	3	]	]	PUNCT
admet-801	267	4	f.	f.	PROPN
admet-801	267	5	podczeck	podczeck	PROPN
admet-801	267	6	.	.	PUNCT
admet-801	268	1	comparison	comparison	NOUN
admet-801	268	2	of	of	ADP
admet-801	268	3	in	in	ADP
admet-801	268	4	vitro	vitro	X
admet-801	268	5	dissolution	dissolution	ADJ
admet-801	268	6	profiles	profile	NOUN
admet-801	268	7	by	by	ADP
admet-801	268	8	calculating	calculate	VERB
admet-801	268	9	mean	mean	NOUN
admet-801	268	10	dissolution	dissolution	ADJ
admet-801	268	11	time	time	NOUN
admet-801	268	12	(	(	PUNCT
admet-801	268	13	mdt	mdt	PROPN
admet-801	268	14	)	)	PUNCT
admet-801	268	15	or	or	CCONJ
admet-801	268	16	mean	mean	VERB
admet-801	268	17	residence	residence	NOUN
admet-801	268	18	time	time	NOUN
admet-801	268	19	(	(	PUNCT
admet-801	268	20	mrt	mrt	PROPN
admet-801	268	21	)	)	PUNCT
admet-801	268	22	.	.	PUNCT
admet-801	269	1	international	international	ADJ
admet-801	269	2	journal	journal	PROPN
admet-801	269	3	of	of	ADP
admet-801	269	4	pharmaceutics	pharmaceutic	NOUN
admet-801	269	5	97	97	NUM
admet-801	269	6	(	(	PUNCT
admet-801	269	7	1993	1993	NUM
admet-801	269	8	)	)	PUNCT
admet-801	269	9	93	93	NUM
admet-801	269	10	-	-	SYM
admet-801	269	11	100	100	NUM
admet-801	269	12	.	.	PUNCT
admet-801	270	1	[	[	X
admet-801	270	2	25	25	NUM
admet-801	270	3	]	]	X
admet-801	270	4	p.	p.	PROPN
admet-801	270	5	costa	costa	PROPN
admet-801	270	6	,	,	PUNCT
admet-801	270	7	j.m	j.m	PROPN
admet-801	270	8	.	.	PROPN
admet-801	270	9	sousa	sousa	PROPN
admet-801	270	10	lobo	lobo	PROPN
admet-801	270	11	.	.	PUNCT
admet-801	271	1	modeling	modeling	NOUN
admet-801	271	2	and	and	CCONJ
admet-801	271	3	comparison	comparison	NOUN
admet-801	271	4	of	of	ADP
admet-801	271	5	dissolution	dissolution	NOUN
admet-801	271	6	profiles	profile	NOUN
admet-801	271	7	.	.	PUNCT
admet-801	272	1	european	european	ADJ
admet-801	272	2	journal	journal	PROPN
admet-801	272	3	of	of	ADP
admet-801	272	4	pharmaceutical	pharmaceutical	PROPN
admet-801	272	5	sciences	science	NOUN
admet-801	272	6	13	13	NUM
admet-801	272	7	(	(	PUNCT
admet-801	272	8	2001	2001	NUM
admet-801	272	9	)	)	PUNCT
admet-801	272	10	123	123	NUM
admet-801	272	11	-	-	SYM
admet-801	272	12	133	133	NUM
admet-801	272	13	.	.	PUNCT
admet-801	273	1	[	[	X
admet-801	273	2	26	26	NUM
admet-801	273	3	]	]	X
admet-801	273	4	y.	y.	PROPN
admet-801	273	5	zhang	zhang	PROPN
admet-801	273	6	,	,	PUNCT
admet-801	273	7	m.	m.	NOUN
admet-801	273	8	huo	huo	PROPN
admet-801	273	9	,	,	PUNCT
admet-801	273	10	j.	j.	PROPN
admet-801	273	11	zhou	zhou	PROPN
admet-801	273	12	,	,	PUNCT
admet-801	273	13	a.	a.	PROPN
admet-801	273	14	zou	zou	PROPN
admet-801	273	15	,	,	PUNCT
admet-801	273	16	w.	w.	PROPN
admet-801	273	17	li	li	PROPN
admet-801	273	18	,	,	PUNCT
admet-801	273	19	c.	c.	PROPN
admet-801	273	20	yao	yao	PROPN
admet-801	273	21	,	,	PUNCT
admet-801	273	22	s.	s.	PROPN
admet-801	273	23	xie	xie	PROPN
admet-801	273	24	.	.	PUNCT
admet-801	274	1	dd	dd	PROPN
admet-801	274	2	solver	solver	ADV
admet-801	274	3	:	:	PUNCT
admet-801	274	4	an	an	DET
admet-801	274	5	add	add	VERB
admet-801	274	6	-	-	PUNCT
admet-801	274	7	in	in	ADP
admet-801	274	8	program	program	NOUN
admet-801	274	9	for	for	ADP
admet-801	274	10	modeling	modeling	NOUN
admet-801	274	11	and	and	CCONJ
admet-801	274	12	comparison	comparison	NOUN
admet-801	274	13	of	of	ADP
admet-801	274	14	drug	drug	NOUN
admet-801	274	15	dissolution	dissolution	NOUN
admet-801	274	16	profiles	profile	NOUN
admet-801	274	17	.	.	PUNCT
admet-801	275	1	the	the	DET
admet-801	275	2	aaps	aaps	PROPN
admet-801	275	3	journal	journal	PROPN
admet-801	275	4	12	12	NUM
admet-801	275	5	(	(	PUNCT
admet-801	275	6	2010	2010	NUM
admet-801	275	7	)	)	PUNCT
admet-801	275	8	263˗271	263˗271	NUM
admet-801	275	9	.	.	PUNCT
admet-801	276	1	[	[	X
admet-801	276	2	27	27	NUM
admet-801	276	3	]	]	X
admet-801	276	4	n.	n.	PROPN
admet-801	276	5	yuksel	yuksel	PROPN
admet-801	276	6	,	,	PUNCT
admet-801	276	7	a.e	a.e	PROPN
admet-801	276	8	.	.	PROPN
admet-801	276	9	kanik	kanik	PROPN
admet-801	276	10	,	,	PUNCT
admet-801	276	11	t.	t.	PROPN
admet-801	276	12	baykara	baykara	PROPN
admet-801	276	13	.	.	PUNCT
admet-801	277	1	comparison	comparison	NOUN
admet-801	277	2	of	of	ADP
admet-801	277	3	in	in	ADP
admet-801	277	4	vitro	vitro	X
admet-801	277	5	dissolution	dissolution	NOUN
admet-801	277	6	profiles	profile	NOUN
admet-801	277	7	by	by	ADP
admet-801	277	8	anova	anova	PROPN
admet-801	277	9	-	-	PUNCT
admet-801	277	10	based	base	VERB
admet-801	277	11	,	,	PUNCT
admet-801	277	12	model	model	NOUN
admet-801	277	13	-	-	PUNCT
admet-801	277	14	dependent	dependent	ADJ
admet-801	277	15	and	and	CCONJ
admet-801	277	16	independent	independent	ADJ
admet-801	277	17	-	-	PUNCT
admet-801	277	18	methods	method	NOUN
admet-801	277	19	.	.	PUNCT
admet-801	278	1	international	international	ADJ
admet-801	278	2	journal	journal	PROPN
admet-801	278	3	of	of	ADP
admet-801	278	4	pharmaceutics	pharmaceutic	NOUN
admet-801	278	5	209	209	NUM
admet-801	278	6	(	(	PUNCT
admet-801	278	7	2000	2000	NUM
admet-801	278	8	)	)	PUNCT
admet-801	278	9	57	57	NUM
admet-801	278	10	-	-	SYM
admet-801	278	11	67	67	NUM
admet-801	278	12	.	.	PUNCT
admet-801	279	1	[	[	X
admet-801	279	2	28	28	NUM
admet-801	279	3	]	]	X
admet-801	279	4	f.	f.	PROPN
admet-801	279	5	langenbucher	langenbucher	PROPN
admet-801	279	6	.	.	PUNCT
admet-801	280	1	linearization	linearization	NOUN
admet-801	280	2	of	of	ADP
admet-801	280	3	dissolution	dissolution	NOUN
admet-801	280	4	curves	curve	NOUN
admet-801	280	5	by	by	ADP
admet-801	280	6	the	the	DET
admet-801	280	7	weibull	weibull	PROPN
admet-801	280	8	distribution	distribution	NOUN
admet-801	280	9	.	.	PUNCT
admet-801	281	1	journal	journal	NOUN
admet-801	281	2	of	of	ADP
admet-801	281	3	pharmacy	pharmacy	NOUN
admet-801	281	4	and	and	CCONJ
admet-801	281	5	pharmacology	pharmacology	NOUN
admet-801	281	6	24	24	NUM
admet-801	281	7	(	(	PUNCT
admet-801	281	8	1972	1972	NUM
admet-801	281	9	)	)	PUNCT
admet-801	281	10	979	979	NUM
admet-801	281	11	-	-	SYM
admet-801	281	12	981	981	NUM
admet-801	281	13	.	.	PUNCT
admet-801	282	1	[	[	X
admet-801	282	2	29	29	NUM
admet-801	282	3	]	]	X
admet-801	282	4	y.	y.	PROPN
admet-801	282	5	wu	wu	PROPN
admet-801	282	6	,	,	PUNCT
admet-801	282	7	d.o	d.o	PROPN
admet-801	282	8	.	.	PROPN
admet-801	282	9	kildsing	kildsing	PROPN
admet-801	282	10	,	,	PUNCT
admet-801	282	11	e.s	e.s	PROPN
admet-801	282	12	.	.	PROPN
admet-801	282	13	ghaly	ghaly	PROPN
admet-801	282	14	.	.	PUNCT
admet-801	283	1	effect	effect	NOUN
admet-801	283	2	of	of	ADP
admet-801	283	3	hydrodynamic	hydrodynamic	ADJ
admet-801	283	4	environment	environment	NOUN
admet-801	283	5	on	on	ADP
admet-801	283	6	tablet	tablet	ADJ
admet-801	283	7	dissolution	dissolution	NOUN
admet-801	283	8	rate	rate	NOUN
admet-801	283	9	.	.	PUNCT
admet-801	284	1	pharmaceutical	pharmaceutical	NOUN
admet-801	284	2	development	development	NOUN
admet-801	284	3	and	and	CCONJ
admet-801	284	4	technology	technology	NOUN
admet-801	284	5	9	9	NUM
admet-801	284	6	(	(	PUNCT
admet-801	284	7	2004	2004	NUM
admet-801	284	8	)	)	PUNCT
admet-801	284	9	25	25	NUM
admet-801	284	10	-	-	SYM
admet-801	284	11	37	37	NUM
admet-801	284	12	.	.	PUNCT
admet-801	285	1	[	[	X
admet-801	285	2	30	30	NUM
admet-801	285	3	]	]	X
admet-801	285	4	v.p	v.p	PROPN
admet-801	285	5	.	.	PROPN
admet-801	285	6	shah	shah	PROPN
admet-801	285	7	,	,	PUNCT
admet-801	285	8	m.	m.	NOUN
admet-801	285	9	gurbarg	gurbarg	NOUN
admet-801	285	10	,	,	PUNCT
admet-801	285	11	a.	a.	NOUN
admet-801	285	12	noory	noory	PROPN
admet-801	285	13	,	,	PUNCT
admet-801	285	14	s.	s.	PROPN
admet-801	285	15	dighe	dighe	PROPN
admet-801	285	16	,	,	PUNCT
admet-801	285	17	j.p	j.p	PROPN
admet-801	285	18	.	.	PROPN
admet-801	285	19	skelly	skelly	PROPN
admet-801	285	20	.	.	PUNCT
admet-801	286	1	influence	influence	NOUN
admet-801	286	2	of	of	ADP
admet-801	286	3	higher	high	ADJ
admet-801	286	4	rates	rate	NOUN
admet-801	286	5	of	of	ADP
admet-801	286	6	agitation	agitation	NOUN
admet-801	286	7	on	on	ADP
admet-801	286	8	release	release	NOUN
admet-801	286	9	patterns	pattern	NOUN
admet-801	286	10	of	of	ADP
admet-801	286	11	immediate	immediate	ADJ
admet-801	286	12	-	-	PUNCT
admet-801	286	13	release	release	NOUN
admet-801	286	14	drug	drug	NOUN
admet-801	286	15	products	product	NOUN
admet-801	286	16	.	.	PUNCT
admet-801	287	1	journal	journal	NOUN
admet-801	287	2	of	of	ADP
admet-801	287	3	pharmaceutical	pharmaceutical	PROPN
admet-801	287	4	sciences	science	NOUN
admet-801	287	5	81	81	NUM
admet-801	287	6	(	(	PUNCT
admet-801	287	7	1992	1992	NUM
admet-801	287	8	)	)	PUNCT
admet-801	287	9	500	500	NUM
admet-801	287	10	-	-	SYM
admet-801	287	11	503	503	NUM
admet-801	287	12	.	.	PUNCT
admet-801	288	1	[	[	X
admet-801	288	2	31	31	NUM
admet-801	288	3	]	]	X
admet-801	288	4	g.	g.	PROPN
admet-801	288	5	levy	levy	PROPN
admet-801	288	6	,	,	PUNCT
admet-801	288	7	b.a	b.a	PROPN
admet-801	288	8	.	.	PROPN
admet-801	288	9	hayes	hayes	PROPN
admet-801	288	10	.	.	PUNCT
admet-801	289	1	physicochemical	physicochemical	ADJ
admet-801	289	2	basis	basis	NOUN
admet-801	289	3	of	of	ADP
admet-801	289	4	the	the	DET
admet-801	289	5	buffered	buffer	VERB
admet-801	289	6	acetylsalicylic	acetylsalicylic	NOUN
admet-801	289	7	acid	acid	PROPN
admet-801	289	8	controversy	controversy	NOUN
admet-801	289	9	.	.	PUNCT
admet-801	290	1	new	new	PROPN
admet-801	290	2	england	england	PROPN
admet-801	290	3	journal	journal	PROPN
admet-801	290	4	of	of	ADP
admet-801	290	5	medicine	medicine	PROPN
admet-801	290	6	262	262	NUM
admet-801	290	7	(	(	PUNCT
admet-801	290	8	1960	1960	NUM
admet-801	290	9	)	)	PUNCT
admet-801	290	10	1053	1053	NUM
admet-801	290	11	-	-	SYM
admet-801	290	12	1058	1058	NUM
admet-801	290	13	.	.	PUNCT
admet-801	291	1	[	[	X
admet-801	291	2	32	32	NUM
admet-801	291	3	]	]	X
admet-801	291	4	g.a	g.a	PROPN
admet-801	291	5	.	.	PROPN
admet-801	291	6	shabir	shabir	PROPN
admet-801	291	7	.	.	PUNCT
admet-801	292	1	evaluation	evaluation	NOUN
admet-801	292	2	of	of	ADP
admet-801	292	3	usp	usp	NOUN
admet-801	292	4	basket	basket	NOUN
admet-801	292	5	and	and	CCONJ
admet-801	292	6	paddle	paddle	VERB
admet-801	292	7	dissolution	dissolution	NOUN
admet-801	292	8	methods	method	NOUN
admet-801	292	9	using	use	VERB
admet-801	292	10	different	different	ADJ
admet-801	292	11	generic	generic	ADJ
admet-801	292	12	atenolol	atenolol	NOUN
admet-801	292	13	tablets	tablet	NOUN
admet-801	292	14	.	.	PUNCT
admet-801	293	1	turkish	turkish	ADJ
admet-801	293	2	journal	journal	NOUN
admet-801	293	3	of	of	ADP
admet-801	293	4	pharmaceutical	pharmaceutical	ADJ
admet-801	293	5	sciences	science	NOUN
admet-801	293	6	8	8	NUM
admet-801	293	7	(	(	PUNCT
admet-801	293	8	2011	2011	NUM
admet-801	293	9	)	)	PUNCT
admet-801	293	10	253	253	NUM
admet-801	293	11	-	-	SYM
admet-801	293	12	260	260	NUM
admet-801	293	13	.	.	PUNCT
admet-801	294	1	[	[	X
admet-801	294	2	33	33	NUM
admet-801	294	3	]	]	PUNCT
admet-801	294	4	z.	z.	PROPN
admet-801	294	5	gao	gao	PROPN
admet-801	294	6	.	.	PUNCT
admet-801	295	1	in	in	ADP
admet-801	295	2	vitro	vitro	X
admet-801	295	3	dissolution	dissolution	NOUN
admet-801	295	4	testing	testing	NOUN
admet-801	295	5	with	with	ADP
admet-801	295	6	flow	flow	NOUN
admet-801	295	7	-	-	PUNCT
admet-801	295	8	through	through	ADP
admet-801	295	9	method	method	NOUN
admet-801	295	10	:	:	PUNCT
admet-801	295	11	a	a	DET
admet-801	295	12	technical	technical	ADJ
admet-801	295	13	note	note	NOUN
admet-801	295	14	.	.	PUNCT
admet-801	296	1	aaps	aap	NOUN
admet-801	296	2	pharmscitech	pharmscitech	VERB
admet-801	296	3	10	10	NUM
admet-801	296	4	(	(	PUNCT
admet-801	296	5	2009	2009	NUM
admet-801	296	6	)	)	PUNCT
admet-801	296	7	1401	1401	NUM
admet-801	296	8	-	-	SYM
admet-801	296	9	1405	1405	NUM
admet-801	296	10	.	.	PUNCT
admet-801	297	1	[	[	X
admet-801	297	2	34	34	NUM
admet-801	297	3	]	]	X
admet-801	297	4	i.	i.	PROPN
admet-801	297	5	singh	singh	PROPN
admet-801	297	6	,	,	PUNCT
admet-801	297	7	h.y	h.y	PROPN
admet-801	297	8	.	.	PROPN
admet-801	297	9	aboul	aboul	PROPN
admet-801	297	10	-	-	PUNCT
admet-801	297	11	eneim	eneim	NOUN
admet-801	297	12	.	.	PUNCT
admet-801	297	13	advantages	advantage	NOUN
admet-801	297	14	of	of	ADP
admet-801	297	15	usp	usp	NOUN
admet-801	297	16	apparatus	apparatus	NOUN
admet-801	297	17	iv	iv	NUM
admet-801	297	18	(	(	PUNCT
admet-801	297	19	flow	flow	NOUN
admet-801	297	20	-	-	PUNCT
admet-801	297	21	through	through	ADP
admet-801	297	22	cell	cell	NOUN
admet-801	297	23	apparatus	apparatus	NOUN
admet-801	297	24	)	)	PUNCT
admet-801	297	25	in	in	ADP
admet-801	297	26	dissolution	dissolution	ADJ
admet-801	297	27	studies	study	NOUN
admet-801	297	28	.	.	PUNCT
admet-801	298	1	journal	journal	PROPN
admet-801	298	2	of	of	ADP
admet-801	298	3	the	the	DET
admet-801	298	4	iranian	iranian	ADJ
admet-801	298	5	chemical	chemical	PROPN
admet-801	298	6	society	society	PROPN
admet-801	298	7	3	3	NUM
admet-801	298	8	(	(	PUNCT
admet-801	298	9	2006	2006	NUM
admet-801	298	10	)	)	PUNCT
admet-801	298	11	220	220	NUM
admet-801	298	12	-	-	SYM
admet-801	298	13	222	222	NUM
admet-801	298	14	.	.	PUNCT
admet-801	299	1	[	[	X
admet-801	299	2	35	35	NUM
admet-801	299	3	]	]	X
admet-801	299	4	j.b	j.b	PROPN
admet-801	299	5	.	.	PROPN
admet-801	299	6	fang	fang	PROPN
admet-801	299	7	,	,	PUNCT
admet-801	299	8	v.k	v.k	PROPN
admet-801	299	9	.	.	PROPN
admet-801	299	10	robertson	robertson	PROPN
admet-801	299	11	,	,	PUNCT
admet-801	299	12	a.	a.	PROPN
admet-801	299	13	rawat	rawat	PROPN
admet-801	299	14	,	,	PUNCT
admet-801	299	15	t.	t.	NOUN
admet-801	299	16	flick	flick	NOUN
admet-801	299	17	,	,	PUNCT
admet-801	299	18	z.j	z.j	PROPN
admet-801	299	19	.	.	PROPN
admet-801	299	20	tang	tang	PROPN
admet-801	299	21	,	,	PUNCT
admet-801	299	22	n.s	n.s	PROPN
admet-801	299	23	.	.	PROPN
admet-801	299	24	cauchon	cauchon	PROPN
admet-801	299	25	,	,	PUNCT
admet-801	299	26	j.s	j.s	PROPN
admet-801	299	27	.	.	PROPN
admet-801	299	28	mcelvain	mcelvain	PROPN
admet-801	299	29	.	.	PUNCT
admet-801	300	1	development	development	NOUN
admet-801	300	2	and	and	CCONJ
admet-801	300	3	application	application	NOUN
admet-801	300	4	of	of	ADP
admet-801	300	5	a	a	DET
admet-801	300	6	biorelevant	biorelevant	ADJ
admet-801	300	7	dissolution	dissolution	NOUN
admet-801	300	8	method	method	NOUN
admet-801	300	9	using	use	VERB
admet-801	300	10	usp	usp	NOUN
admet-801	300	11	apparatus	apparatus	NOUN
admet-801	300	12	4	4	NUM
admet-801	300	13	in	in	ADP
admet-801	300	14	early	early	ADJ
admet-801	300	15	phase	phase	NOUN
admet-801	300	16	formulation	formulation	NOUN
admet-801	300	17	development	development	NOUN
admet-801	300	18	.	.	PUNCT
admet-801	301	1	molecular	molecular	ADJ
admet-801	301	2	pharmaceutics	pharmaceutic	NOUN
admet-801	301	3	7	7	NUM
admet-801	301	4	(	(	PUNCT
admet-801	301	5	2010	2010	NUM
admet-801	301	6	)	)	PUNCT
admet-801	301	7	1466	1466	NUM
admet-801	301	8	-	-	SYM
admet-801	301	9	1477	1477	NUM
admet-801	301	10	.	.	PUNCT
admet-801	302	1	[	[	X
admet-801	302	2	36	36	NUM
admet-801	302	3	]	]	X
admet-801	302	4	b.	b.	PROPN
admet-801	302	5	steffansen	steffansen	PROPN
admet-801	302	6	,	,	PUNCT
admet-801	302	7	b.	b.	PROPN
admet-801	302	8	brodin	brodin	PROPN
admet-801	302	9	,	,	PUNCT
admet-801	302	10	c.	c.	PROPN
admet-801	302	11	und	und	PROPN
admet-801	302	12	nielsen	nielsen	PROPN
admet-801	302	13	.	.	PUNCT
admet-801	303	1	molecular	molecular	ADJ
admet-801	303	2	biopharmaceutics	biopharmaceutic	NOUN
admet-801	303	3	:	:	PUNCT
admet-801	303	4	aspects	aspect	NOUN
admet-801	303	5	of	of	ADP
admet-801	303	6	drug	drug	NOUN
admet-801	303	7	characterization	characterization	NOUN
admet-801	303	8	,	,	PUNCT
admet-801	303	9	drug	drug	NOUN
admet-801	303	10	delivery	delivery	NOUN
admet-801	303	11	and	and	CCONJ
admet-801	303	12	dosage	dosage	NOUN
admet-801	303	13	form	form	NOUN
admet-801	303	14	evaluation	evaluation	NOUN
admet-801	303	15	.	.	PUNCT
admet-801	304	1	ulla	ulla	PROPN
admet-801	304	2	pharmacy	pharmacy	NOUN
admet-801	304	3	series	series	PROPN
admet-801	304	4	.	.	PUNCT
admet-801	305	1	pharmaceutical	pharmaceutical	PROPN
admet-801	305	2	press	press	PROPN
admet-801	305	3	.	.	PUNCT
admet-801	306	1	london	london	PROPN
admet-801	306	2	,	,	PUNCT
admet-801	306	3	united	united	PROPN
admet-801	306	4	kingdom	kingdom	PROPN
admet-801	306	5	.	.	PUNCT
admet-801	307	1	2009	2009	NUM
admet-801	307	2	.	.	PUNCT
admet-801	308	1	[	[	X
admet-801	308	2	37	37	NUM
admet-801	308	3	]	]	X
admet-801	308	4	c.	c.	PROPN
admet-801	308	5	larsen	larsen	PROPN
admet-801	308	6	,	,	PUNCT
admet-801	308	7	s.w	s.w	PROPN
admet-801	308	8	.	.	PROPN
admet-801	308	9	larsen	larsen	PROPN
admet-801	308	10	,	,	PUNCT
admet-801	308	11	h.	h.	PROPN
admet-801	308	12	jensen	jensen	PROPN
admet-801	308	13	,	,	PUNCT
admet-801	308	14	a.	a.	NOUN
admet-801	308	15	yaghmur	yaghmur	PROPN
admet-801	308	16	,	,	PUNCT
admet-801	308	17	j.	j.	PROPN
admet-801	308	18	østergaard	østergaard	PROPN
admet-801	308	19	.	.	PUNCT
admet-801	309	1	role	role	NOUN
admet-801	309	2	of	of	ADP
admet-801	309	3	in	in	ADP
admet-801	309	4	vitro	vitro	X
admet-801	309	5	release	release	NOUN
admet-801	309	6	models	model	NOUN
admet-801	309	7	in	in	ADP
admet-801	309	8	formulation	formulation	NOUN
admet-801	309	9	development	development	NOUN
admet-801	309	10	and	and	CCONJ
admet-801	309	11	quality	quality	NOUN
admet-801	309	12	control	control	NOUN
admet-801	309	13	of	of	ADP
admet-801	309	14	parenteral	parenteral	ADJ
admet-801	309	15	depots	depot	NOUN
admet-801	309	16	.	.	PUNCT
admet-801	310	1	expert	expert	ADJ
admet-801	310	2	opinion	opinion	NOUN
admet-801	310	3	on	on	ADP
admet-801	310	4	drug	drug	NOUN
admet-801	310	5	delivery	delivery	NOUN
admet-801	310	6	6	6	NUM
admet-801	310	7	(	(	PUNCT
admet-801	310	8	2009	2009	NUM
admet-801	310	9	)	)	PUNCT
admet-801	310	10	1283	1283	NUM
admet-801	310	11	-	-	SYM
admet-801	310	12	1295	1295	NUM
admet-801	310	13	.	.	PUNCT
admet-801	311	1	https://www.gob.mx/cms/uploads/attachment/file/441323/listado_de_medicamentos_de_referencia_.pdf	https://www.gob.mx/cms/uploads/attachment/file/441323/listado_de_medicamentos_de_referencia_.pdf	PROPN
admet-801	311	2	https://www.gob.mx/cms/uploads/attachment/file/441323/listado_de_medicamentos_de_referencia_.pdf	https://www.gob.mx/cms/uploads/attachment/file/441323/listado_de_medicamentos_de_referencia_.pdf	PROPN
admet-801	311	3	admet	admet	PROPN
admet-801	311	4	&	&	CCONJ
admet-801	311	5	dmpk	dmpk	PROPN
admet-801	311	6	8(4	8(4	NOUN
admet-801	311	7	)	)	PUNCT
admet-801	311	8	(	(	PUNCT
admet-801	311	9	2020	2020	NUM
admet-801	311	10	)	)	PUNCT
admet-801	311	11	411	411	NUM
admet-801	311	12	-	-	SYM
admet-801	311	13	423	423	NUM
admet-801	311	14	in	in	ADP
admet-801	311	15	vitro	vitro	X
admet-801	311	16	release	release	NOUN
admet-801	311	17	studies	study	NOUN
admet-801	311	18	of	of	ADP
admet-801	311	19	furosemide	furosemide	ADJ
admet-801	311	20	doi	doi	NOUN
admet-801	311	21	:	:	PUNCT
admet-801	311	22	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	NOUN
admet-801	311	23	423	423	NUM
admet-801	311	24	[	[	X
admet-801	311	25	38	38	NUM
admet-801	311	26	]	]	X
admet-801	311	27	j.h	j.h	PROPN
admet-801	311	28	.	.	PROPN
admet-801	311	29	fagerberg	fagerberg	PROPN
admet-801	311	30	,	,	PUNCT
admet-801	311	31	o.	o.	PROPN
admet-801	311	32	tsinman	tsinman	NOUN
admet-801	311	33	,	,	PUNCT
admet-801	311	34	n.	n.	PROPN
admet-801	311	35	sun	sun	PROPN
admet-801	311	36	,	,	PUNCT
admet-801	311	37	k.	k.	PROPN
admet-801	311	38	tsinman	tsinman	PROPN
admet-801	311	39	,	,	PUNCT
admet-801	311	40	a.	a.	PROPN
admet-801	311	41	avdeef	avdeef	PROPN
admet-801	311	42	,	,	PUNCT
admet-801	311	43	c.a.s	c.a.	VERB
admet-801	311	44	.	.	PROPN
admet-801	311	45	bergström	bergström	PROPN
admet-801	311	46	.	.	PUNCT
admet-801	312	1	dissolution	dissolution	NOUN
admet-801	312	2	rate	rate	NOUN
admet-801	312	3	and	and	CCONJ
admet-801	312	4	apparent	apparent	ADJ
admet-801	312	5	solubility	solubility	NOUN
admet-801	312	6	of	of	ADP
admet-801	312	7	poorly	poorly	ADV
admet-801	312	8	soluble	soluble	ADJ
admet-801	312	9	drugs	drug	NOUN
admet-801	312	10	in	in	ADP
admet-801	312	11	biorelevant	biorelevant	ADJ
admet-801	312	12	dissolution	dissolution	NOUN
admet-801	312	13	media	medium	NOUN
admet-801	312	14	.	.	PUNCT
admet-801	313	1	molecular	molecular	ADJ
admet-801	313	2	pharmaceutics	pharmaceutic	NOUN
admet-801	313	3	7	7	NUM
admet-801	313	4	(	(	PUNCT
admet-801	313	5	2010	2010	NUM
admet-801	313	6	)	)	PUNCT
admet-801	313	7	1419	1419	NUM
admet-801	313	8	-	-	SYM
admet-801	313	9	1430	1430	NUM
admet-801	313	10	.	.	PUNCT
admet-801	314	1	[	[	X
admet-801	314	2	39	39	NUM
admet-801	314	3	]	]	PUNCT
admet-801	314	4	us	us	PROPN
admet-801	314	5	dhhs	dhhs	PROPN
admet-801	314	6	,	,	PUNCT
admet-801	314	7	fda	fda	PROPN
admet-801	314	8	,	,	PUNCT
admet-801	314	9	cder	cder	NOUN
admet-801	314	10	,	,	PUNCT
admet-801	314	11	guidance	guidance	NOUN
admet-801	314	12	for	for	ADP
admet-801	314	13	industry	industry	NOUN
admet-801	314	14	:	:	PUNCT
admet-801	314	15	waiver	waiver	NOUN
admet-801	314	16	if	if	SCONJ
admet-801	314	17	in	in	ADP
admet-801	314	18	vivo	vivo	ADJ
admet-801	314	19	bioavailability	bioavailability	NOUN
admet-801	314	20	and	and	CCONJ
admet-801	314	21	bioequivalence	bioequivalence	NOUN
admet-801	314	22	studies	study	NOUN
admet-801	314	23	for	for	ADP
admet-801	314	24	immediate	immediate	ADJ
admet-801	314	25	-	-	PUNCT
admet-801	314	26	release	release	NOUN
admet-801	314	27	solid	solid	ADJ
admet-801	314	28	oral	oral	ADJ
admet-801	314	29	dosage	dosage	NOUN
admet-801	314	30	forms	form	NOUN
admet-801	314	31	based	base	VERB
admet-801	314	32	on	on	ADP
admet-801	314	33	a	a	DET
admet-801	314	34	biopharmaceutics	biopharmaceutics	NOUN
admet-801	314	35	classification	classification	NOUN
admet-801	314	36	system	system	NOUN
admet-801	314	37	,	,	PUNCT
admet-801	314	38	u.s	u.s	PROPN
admet-801	314	39	.	.	PROPN
admet-801	314	40	department	department	PROPN
admet-801	314	41	of	of	ADP
admet-801	314	42	health	health	PROPN
admet-801	314	43	and	and	CCONJ
admet-801	314	44	human	human	ADJ
admet-801	314	45	services	service	NOUN
admet-801	314	46	,	,	PUNCT
admet-801	314	47	food	food	NOUN
admet-801	314	48	and	and	CCONJ
admet-801	314	49	drug	drug	NOUN
admet-801	314	50	administration	administration	NOUN
admet-801	314	51	,	,	PUNCT
admet-801	314	52	center	center	NOUN
admet-801	314	53	for	for	ADP
admet-801	314	54	drug	drug	NOUN
admet-801	314	55	evaluation	evaluation	NOUN
admet-801	314	56	and	and	CCONJ
admet-801	314	57	research	research	NOUN
admet-801	314	58	(	(	PUNCT
admet-801	314	59	cder	cder	NOUN
admet-801	314	60	)	)	PUNCT
admet-801	314	61	(	(	PUNCT
admet-801	314	62	2017	2017	NUM
admet-801	314	63	)	)	PUNCT
admet-801	314	64	,	,	PUNCT
admet-801	314	65	rockville	rockville	PROPN
admet-801	314	66	,	,	PUNCT
admet-801	314	67	md	md	PROPN
admet-801	314	68	,	,	PUNCT
admet-801	314	69	usa	usa	PROPN
admet-801	314	70	.	.	PUNCT
admet-801	315	1	[	[	X
admet-801	315	2	40	40	NUM
admet-801	315	3	]	]	PUNCT
admet-801	315	4	s.	s.	PROPN
admet-801	315	5	missaghi	missaghi	PROPN
admet-801	315	6	,	,	PUNCT
admet-801	315	7	r.	r.	PROPN
admet-801	315	8	fassihi	fassihi	PROPN
admet-801	315	9	.	.	PUNCT
admet-801	316	1	release	release	NOUN
admet-801	316	2	characterization	characterization	NOUN
admet-801	316	3	of	of	ADP
admet-801	316	4	dimenhydrinate	dimenhydrinate	NOUN
admet-801	316	5	from	from	ADP
admet-801	316	6	an	an	DET
admet-801	316	7	eroding	eroding	ADJ
admet-801	316	8	and	and	CCONJ
admet-801	316	9	swelling	swell	VERB
admet-801	316	10	matrix	matrix	NOUN
admet-801	316	11	:	:	PUNCT
admet-801	316	12	selection	selection	NOUN
admet-801	316	13	of	of	ADP
admet-801	316	14	appropriate	appropriate	ADJ
admet-801	316	15	dissolution	dissolution	NOUN
admet-801	316	16	apparatus	apparatus	NOUN
admet-801	316	17	.	.	PUNCT
admet-801	317	1	international	international	ADJ
admet-801	317	2	journal	journal	PROPN
admet-801	317	3	of	of	ADP
admet-801	317	4	pharmaceutics	pharmaceutic	NOUN
admet-801	317	5	29	29	NUM
admet-801	317	6	(	(	PUNCT
admet-801	317	7	2005	2005	NUM
admet-801	317	8	)	)	PUNCT
admet-801	317	9	35	35	NUM
admet-801	317	10	-	-	SYM
admet-801	317	11	42	42	NUM
admet-801	317	12	.	.	PUNCT
admet-801	318	1	[	[	X
admet-801	318	2	41	41	NUM
admet-801	318	3	]	]	X
admet-801	318	4	e.	e.	PROPN
admet-801	318	5	adams	adams	PROPN
admet-801	318	6	,	,	PUNCT
admet-801	318	7	d.	d.	PROPN
admet-801	318	8	coomans	coomans	PROPN
admet-801	318	9	,	,	PUNCT
admet-801	318	10	j.	j.	PROPN
admet-801	318	11	smeyers	smeyers	PROPN
admet-801	318	12	-	-	PUNCT
admet-801	318	13	verbeke	verbeke	ADJ
admet-801	318	14	,	,	PUNCT
admet-801	318	15	d.l	d.l	PROPN
admet-801	318	16	.	.	PROPN
admet-801	318	17	massart	massart	PROPN
admet-801	318	18	.	.	PUNCT
admet-801	319	1	non	non	ADJ
admet-801	319	2	-	-	ADJ
admet-801	319	3	linear	linear	ADJ
admet-801	319	4	mixed	mixed	ADJ
admet-801	319	5	effects	effect	NOUN
admet-801	319	6	models	model	NOUN
admet-801	319	7	for	for	ADP
admet-801	319	8	the	the	DET
admet-801	319	9	evaluation	evaluation	NOUN
admet-801	319	10	of	of	ADP
admet-801	319	11	dissolution	dissolution	NOUN
admet-801	319	12	profiles	profile	NOUN
admet-801	319	13	.	.	PUNCT
admet-801	320	1	international	international	ADJ
admet-801	320	2	journal	journal	PROPN
admet-801	320	3	of	of	ADP
admet-801	320	4	pharmaceutics	pharmaceutic	NOUN
admet-801	320	5	240	240	NUM
admet-801	320	6	(	(	PUNCT
admet-801	320	7	2002	2002	NUM
admet-801	320	8	)	)	PUNCT
admet-801	320	9	37	37	NUM
admet-801	320	10	-	-	SYM
admet-801	320	11	53	53	NUM
admet-801	320	12	.	.	PUNCT
admet-801	321	1	[	[	X
admet-801	321	2	42	42	NUM
admet-801	321	3	]	]	X
admet-801	321	4	y.k	y.k	PROPN
admet-801	321	5	.	.	PROPN
admet-801	321	6	han	han	PROPN
admet-801	321	7	,	,	PUNCT
admet-801	321	8	l.d	l.d	PROPN
admet-801	321	9	.	.	PROPN
admet-801	321	10	simionato	simionato	PROPN
admet-801	321	11	,	,	PUNCT
admet-801	321	12	r.g	r.g	PROPN
admet-801	321	13	.	.	PROPN
admet-801	321	14	calvo	calvo	PROPN
admet-801	321	15	,	,	PUNCT
admet-801	321	16	m.b	m.b	PROPN
admet-801	321	17	.	.	PROPN
admet-801	321	18	mattei	mattei	PROPN
admet-801	321	19	,	,	PUNCT
admet-801	321	20	a.i	a.i	PROPN
admet-801	321	21	.	.	PROPN
admet-801	321	22	segall	segall	PROPN
admet-801	321	23	.	.	PUNCT
admet-801	322	1	comparison	comparison	NOUN
admet-801	322	2	of	of	ADP
admet-801	322	3	dissolution	dissolution	ADJ
admet-801	322	4	profiles	profile	NOUN
admet-801	322	5	of	of	ADP
admet-801	322	6	furosemide	furosemide	ADJ
admet-801	322	7	tablets	tablet	NOUN
admet-801	322	8	available	available	ADJ
admet-801	322	9	in	in	ADP
admet-801	322	10	the	the	DET
admet-801	322	11	argentinian	argentinian	ADJ
admet-801	322	12	market	market	NOUN
admet-801	322	13	.	.	PUNCT
admet-801	323	1	journal	journal	NOUN
admet-801	323	2	of	of	ADP
admet-801	323	3	applied	apply	VERB
admet-801	323	4	solution	solution	NOUN
admet-801	323	5	chemistry	chemistry	NOUN
admet-801	323	6	and	and	CCONJ
admet-801	323	7	modeling	model	VERB
admet-801	323	8	3	3	NUM
admet-801	323	9	(	(	PUNCT
admet-801	323	10	2014	2014	NUM
admet-801	323	11	)	)	PUNCT
admet-801	323	12	186	186	NUM
admet-801	323	13	-	-	SYM
admet-801	323	14	193	193	NUM
admet-801	323	15	.	.	PUNCT
admet-801	324	1	[	[	X
admet-801	324	2	43	43	NUM
admet-801	324	3	]	]	X
admet-801	324	4	j.r	j.r	PROPN
admet-801	324	5	.	.	PROPN
admet-801	324	6	medina	medina	PROPN
admet-801	324	7	,	,	PUNCT
admet-801	324	8	d.k	d.k	PROPN
admet-801	324	9	.	.	PROPN
admet-801	324	10	salazar	salazar	PROPN
admet-801	324	11	,	,	PUNCT
admet-801	324	12	m.	m.	NOUN
admet-801	324	13	hurtado	hurtado	NOUN
admet-801	324	14	,	,	PUNCT
admet-801	324	15	a.r	a.r	PROPN
admet-801	324	16	.	.	PROPN
admet-801	324	17	cortés	cortés	PROPN
admet-801	324	18	,	,	PUNCT
admet-801	324	19	a.m.	a.m.	PROPN
admet-801	324	20	domínguez	domínguez	NOUN
admet-801	324	21	-	-	PUNCT
admet-801	324	22	ramírez	ramírez	NOUN
admet-801	324	23	.	.	PUNCT
admet-801	325	1	comparative	comparative	ADJ
admet-801	325	2	in	in	ADP
admet-801	325	3	vitro	vitro	X
admet-801	325	4	dissolution	dissolution	NOUN
admet-801	325	5	study	study	NOUN
admet-801	325	6	of	of	ADP
admet-801	325	7	carbamazepine	carbamazepine	NOUN
admet-801	325	8	immediate	immediate	ADJ
admet-801	325	9	-	-	PUNCT
admet-801	325	10	release	release	NOUN
admet-801	325	11	products	product	NOUN
admet-801	325	12	using	use	VERB
admet-801	325	13	the	the	DET
admet-801	325	14	usp	usp	NOUN
admet-801	325	15	paddles	paddle	NOUN
admet-801	325	16	method	method	NOUN
admet-801	325	17	and	and	CCONJ
admet-801	325	18	the	the	DET
admet-801	325	19	flow	flow	NOUN
admet-801	325	20	-	-	PUNCT
admet-801	325	21	through	through	ADP
admet-801	325	22	cell	cell	NOUN
admet-801	325	23	system	system	NOUN
admet-801	325	24	.	.	PUNCT
admet-801	326	1	saudi	saudi	ADJ
admet-801	326	2	pharmaceutical	pharmaceutical	PROPN
admet-801	326	3	journal	journal	PROPN
admet-801	326	4	22	22	NUM
admet-801	326	5	(	(	PUNCT
admet-801	326	6	2014	2014	NUM
admet-801	326	7	)	)	PUNCT
admet-801	326	8	141	141	NUM
admet-801	326	9	-	-	SYM
admet-801	326	10	147	147	NUM
admet-801	326	11	.	.	PUNCT
admet-801	327	1	[	[	X
admet-801	327	2	44	44	NUM
admet-801	327	3	]	]	X
admet-801	327	4	j.r	j.r	PROPN
admet-801	327	5	.	.	PROPN
admet-801	327	6	medina	medina	PROPN
admet-801	327	7	-	-	PUNCT
admet-801	327	8	lópez	lópez	PROPN
admet-801	327	9	,	,	PUNCT
admet-801	327	10	j.a	j.a	PROPN
admet-801	327	11	.	.	PROPN
admet-801	327	12	orozco	orozco	PROPN
admet-801	327	13	-	-	PUNCT
admet-801	327	14	juárez	juárez	PROPN
admet-801	327	15	,	,	PUNCT
admet-801	327	16	m.	m.	NOUN
admet-801	327	17	hurtado	hurtado	NOUN
admet-801	327	18	.	.	PUNCT
admet-801	328	1	dissolution	dissolution	ADJ
admet-801	328	2	performance	performance	NOUN
admet-801	328	3	of	of	ADP
admet-801	328	4	meloxicam	meloxicam	NOUN
admet-801	328	5	formulations	formulation	NOUN
admet-801	328	6	under	under	ADP
admet-801	328	7	hydrodynamics	hydrodynamic	NOUN
admet-801	328	8	of	of	ADP
admet-801	328	9	usp	usp	NOUN
admet-801	328	10	paddle	paddle	NOUN
admet-801	328	11	apparatus	apparatus	NOUN
admet-801	328	12	and	and	CCONJ
admet-801	328	13	flow	flow	NOUN
admet-801	328	14	-	-	PUNCT
admet-801	328	15	through	through	ADP
admet-801	328	16	cell	cell	NOUN
admet-801	328	17	method	method	NOUN
admet-801	328	18	.	.	PUNCT
admet-801	329	1	international	international	ADJ
admet-801	329	2	journal	journal	PROPN
admet-801	329	3	of	of	ADP
admet-801	329	4	applied	apply	VERB
admet-801	329	5	pharmaceutics	pharmaceutic	NOUN
admet-801	329	6	11	11	NUM
admet-801	329	7	(	(	PUNCT
admet-801	329	8	2019	2019	NUM
admet-801	329	9	)	)	PUNCT
admet-801	329	10	182	182	NUM
admet-801	329	11	-	-	SYM
admet-801	329	12	188	188	NUM
admet-801	329	13	.	.	PUNCT
admet-801	330	1	[	[	X
admet-801	330	2	45	45	NUM
admet-801	330	3	]	]	X
admet-801	330	4	j.r	j.r	PROPN
admet-801	330	5	.	.	PROPN
admet-801	330	6	medina	medina	PROPN
admet-801	330	7	,	,	PUNCT
admet-801	330	8	a.	a.	PROPN
admet-801	330	9	uribe	uribe	PROPN
admet-801	330	10	,	,	PUNCT
admet-801	330	11	m.	m.	NOUN
admet-801	330	12	hurtado	hurtado	NOUN
admet-801	330	13	,	,	PUNCT
admet-801	330	14	a.m.	a.m.	PROPN
admet-801	330	15	domínguez	domínguez	NOUN
admet-801	330	16	-	-	PUNCT
admet-801	330	17	ramírez	ramírez	NOUN
admet-801	330	18	.	.	PUNCT
admet-801	331	1	in	in	ADP
admet-801	331	2	vitro	vitro	X
admet-801	331	3	equivalence	equivalence	NOUN
admet-801	331	4	study	study	NOUN
admet-801	331	5	of	of	ADP
admet-801	331	6	generic	generic	ADJ
admet-801	331	7	naproxen	naproxen	NOUN
admet-801	331	8	tablets	tablet	NOUN
admet-801	331	9	using	use	VERB
admet-801	331	10	the	the	DET
admet-801	331	11	usp	usp	NOUN
admet-801	331	12	paddle	paddle	NOUN
admet-801	331	13	apparatus	apparatus	NOUN
admet-801	331	14	and	and	CCONJ
admet-801	331	15	the	the	DET
admet-801	331	16	flow	flow	NOUN
admet-801	331	17	-	-	PUNCT
admet-801	331	18	through	through	ADP
admet-801	331	19	cell	cell	NOUN
admet-801	331	20	method	method	NOUN
admet-801	331	21	.	.	PUNCT
admet-801	332	1	international	international	ADJ
admet-801	332	2	journal	journal	PROPN
admet-801	332	3	of	of	ADP
admet-801	332	4	pharmacy	pharmacy	NOUN
admet-801	332	5	and	and	CCONJ
admet-801	332	6	pharmaceutical	pharmaceutical	NOUN
admet-801	332	7	sciences	science	NOUN
admet-801	332	8	7	7	NUM
admet-801	332	9	(	(	PUNCT
admet-801	332	10	2015	2015	NUM
admet-801	332	11	)	)	PUNCT
admet-801	332	12	348	348	NUM
admet-801	332	13	-	-	SYM
admet-801	332	14	354	354	NUM
admet-801	332	15	.	.	PUNCT
admet-801	333	1	[	[	X
admet-801	333	2	46	46	NUM
admet-801	333	3	]	]	X
admet-801	333	4	j.r	j.r	PROPN
admet-801	333	5	.	.	PROPN
admet-801	333	6	medina	medina	PROPN
admet-801	333	7	,	,	PUNCT
admet-801	333	8	m.	m.	NOUN
admet-801	333	9	cortes	cortes	PROPN
admet-801	333	10	,	,	PUNCT
admet-801	333	11	e.	e.	PROPN
admet-801	333	12	romo	romo	PROPN
admet-801	333	13	.	.	PUNCT
admet-801	334	1	comparison	comparison	NOUN
admet-801	334	2	of	of	ADP
admet-801	334	3	the	the	DET
admet-801	334	4	usp	usp	NOUN
admet-801	334	5	apparatus	apparatus	NOUN
admet-801	334	6	2	2	NUM
admet-801	334	7	and	and	CCONJ
admet-801	334	8	4	4	NUM
admet-801	334	9	for	for	ADP
admet-801	334	10	testing	test	VERB
admet-801	334	11	the	the	DET
admet-801	334	12	in	in	ADV
admet-801	334	13	vitro	vitro	X
admet-801	334	14	release	release	NOUN
admet-801	334	15	performance	performance	NOUN
admet-801	334	16	of	of	ADP
admet-801	334	17	ibuprofen	ibuprofen	NOUN
admet-801	334	18	generic	generic	ADJ
admet-801	334	19	suspension	suspension	NOUN
admet-801	334	20	.	.	PUNCT
admet-801	335	1	international	international	ADJ
admet-801	335	2	journal	journal	PROPN
admet-801	335	3	of	of	ADP
admet-801	335	4	applied	apply	VERB
admet-801	335	5	pharmaceutics	pharmaceutic	NOUN
admet-801	335	6	9	9	NUM
admet-801	335	7	(	(	PUNCT
admet-801	335	8	2017	2017	NUM
admet-801	335	9	)	)	PUNCT
admet-801	335	10	90	90	NUM
admet-801	335	11	-	-	SYM
admet-801	335	12	95	95	NUM
admet-801	335	13	.	.	PUNCT
admet-801	336	1	©	©	PROPN
admet-801	336	2	2020	2020	NUM
admet-801	336	3	by	by	ADP
admet-801	336	4	the	the	DET
admet-801	336	5	authors	author	NOUN
admet-801	336	6	;	;	PUNCT
admet-801	336	7	licensee	licensee	PROPN
admet-801	336	8	iapc	iapc	PROPN
admet-801	336	9	,	,	PUNCT
admet-801	336	10	zagreb	zagreb	PROPN
admet-801	336	11	,	,	PUNCT
admet-801	336	12	croatia	croatia	PROPN
admet-801	336	13	.	.	PUNCT
admet-801	337	1	this	this	DET
admet-801	337	2	article	article	NOUN
admet-801	337	3	is	be	AUX
admet-801	337	4	an	an	DET
admet-801	337	5	open	open	ADJ
admet-801	337	6	-	-	PUNCT
admet-801	337	7	access	access	NOUN
admet-801	337	8	article	article	NOUN
admet-801	337	9	distributed	distribute	VERB
admet-801	337	10	under	under	ADP
admet-801	337	11	the	the	DET
admet-801	337	12	terms	term	NOUN
admet-801	337	13	and	and	CCONJ
admet-801	337	14	conditions	condition	NOUN
admet-801	337	15	of	of	ADP
admet-801	337	16	the	the	DET
admet-801	337	17	creative	creative	ADJ
admet-801	337	18	commons	common	NOUN
admet-801	337	19	attribution	attribution	NOUN
admet-801	337	20	license	license	NOUN
admet-801	337	21	(	(	PUNCT
admet-801	337	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-801	337	23	)	)	PUNCT
admet-801	337	24	http://dx.doi.org/10.5599/admet.801	http://dx.doi.org/10.5599/admet.801	VERB
admet-801	337	25	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN