id	sid	tid	token	lemma	pos
admet-839	1	1	image	image	NOUN
admet-839	1	2	-	-	PUNCT
admet-839	1	3	based	base	VERB
admet-839	1	4	dissolution	dissolution	ADJ
admet-839	1	5	analysis	analysis	NOUN
admet-839	1	6	for	for	ADP
admet-839	1	7	tracking	track	VERB
admet-839	1	8	the	the	DET
admet-839	1	9	surface	surface	NOUN
admet-839	1	10	stability	stability	NOUN
admet-839	1	11	of	of	ADP
admet-839	1	12	amorphous	amorphous	ADJ
admet-839	1	13	powders	powder	NOUN
admet-839	1	14	doi	doi	NOUN
admet-839	1	15	:	:	PUNCT
admet-839	1	16	https://dx.doi.org/10.5599/admet.839	https://dx.doi.org/10.5599/admet.839	NOUN
admet-839	1	17	401	401	NUM
admet-839	1	18	admet	admet	X
admet-839	1	19	&	&	CCONJ
admet-839	1	20	dmpk	dmpk	PROPN
admet-839	1	21	8(4	8(4	NOUN
admet-839	1	22	)	)	PUNCT
admet-839	1	23	(	(	PUNCT
admet-839	1	24	2020	2020	NUM
admet-839	1	25	)	)	PUNCT
admet-839	1	26	401	401	NUM
admet-839	1	27	-	-	SYM
admet-839	1	28	409	409	NUM
admet-839	1	29	;	;	PUNCT
admet-839	1	30	doi	doi	NOUN
admet-839	1	31	:	:	PUNCT
admet-839	1	32	https://doi.org/10.5599/admet.839	https://doi.org/10.5599/admet.839	PROPN
admet-839	1	33	open	open	ADJ
admet-839	1	34	access	access	NOUN
admet-839	1	35	:	:	PUNCT
admet-839	1	36	issn	issn	PROPN
admet-839	1	37	:	:	PUNCT
admet-839	1	38	1848	1848	NUM
admet-839	1	39	-	-	SYM
admet-839	1	40	7718	7718	NUM
admet-839	1	41	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-839	1	42	original	original	ADJ
admet-839	1	43	scientific	scientific	ADJ
admet-839	1	44	paper	paper	NOUN
admet-839	1	45	image	image	NOUN
admet-839	1	46	-	-	PUNCT
admet-839	1	47	based	base	VERB
admet-839	1	48	dissolution	dissolution	ADJ
admet-839	1	49	analysis	analysis	NOUN
admet-839	1	50	for	for	ADP
admet-839	1	51	tracking	track	VERB
admet-839	1	52	the	the	DET
admet-839	1	53	surface	surface	NOUN
admet-839	1	54	stability	stability	NOUN
admet-839	1	55	of	of	ADP
admet-839	1	56	amorphous	amorphous	ADJ
admet-839	1	57	powders	powder	NOUN
admet-839	1	58	jernej	jernej	PROPN
admet-839	1	59	štukelj*1,2	štukelj*1,2	PROPN
admet-839	1	60	,	,	PUNCT
admet-839	1	61	mikael	mikael	PROPN
admet-839	1	62	agopov2	agopov2	PROPN
admet-839	1	63	,	,	PUNCT
admet-839	1	64	jouko	jouko	PROPN
admet-839	1	65	yliruusi2	yliruusi2	PROPN
admet-839	1	66	,	,	PUNCT
admet-839	1	67	clare	clare	PROPN
admet-839	1	68	j.	j.	PROPN
admet-839	1	69	strachan1	strachan1	PROPN
admet-839	1	70	and	and	CCONJ
admet-839	1	71	sami	sami	PROPN
admet-839	1	72	svanbäck2	svanbäck2	PROPN
admet-839	2	1	1	1	NUM
admet-839	2	2	division	division	NOUN
admet-839	2	3	of	of	ADP
admet-839	2	4	pharmaceutical	pharmaceutical	ADJ
admet-839	2	5	chemistry	chemistry	NOUN
admet-839	2	6	and	and	CCONJ
admet-839	2	7	technology	technology	NOUN
admet-839	2	8	,	,	PUNCT
admet-839	2	9	university	university	PROPN
admet-839	2	10	of	of	ADP
admet-839	2	11	helsinki	helsinki	PROPN
admet-839	2	12	,	,	PUNCT
admet-839	2	13	viikinkaari	viikinkaari	PROPN
admet-839	2	14	5e	5e	NOUN
admet-839	2	15	,	,	PUNCT
admet-839	2	16	00790	00790	NUM
admet-839	2	17	helsinki	helsinki	PROPN
admet-839	2	18	,	,	PUNCT
admet-839	2	19	finland	finland	PROPN
admet-839	2	20	2	2	NUM
admet-839	2	21	the	the	DET
admet-839	2	22	solubility	solubility	NOUN
admet-839	2	23	company	company	NOUN
admet-839	2	24	oy	oy	NOUN
admet-839	2	25	,	,	PUNCT
admet-839	2	26	viikinkaari	viikinkaari	PROPN
admet-839	2	27	4	4	NUM
admet-839	2	28	,	,	PUNCT
admet-839	2	29	00790	00790	NUM
admet-839	2	30	helsinki	helsinki	PROPN
admet-839	2	31	,	,	PUNCT
admet-839	2	32	finland	finland	PROPN
admet-839	2	33	*	*	PUNCT
admet-839	2	34	corresponding	correspond	VERB
admet-839	2	35	author	author	NOUN
admet-839	2	36	:	:	PUNCT
admet-839	2	37	e	e	NOUN
admet-839	2	38	-	-	NOUN
admet-839	2	39	mail	mail	NOUN
admet-839	2	40	:	:	PUNCT
admet-839	2	41	jernej.stukelj@helsinki.fi	jernej.stukelj@helsinki.fi	PROPN
admet-839	2	42	;	;	PUNCT
admet-839	2	43	tel	tel	PROPN
admet-839	2	44	.	.	PUNCT
admet-839	2	45	:	:	PUNCT
admet-839	3	1	+358	+358	NUM
admet-839	3	2	-	-	SYM
admet-839	3	3	29	29	NUM
admet-839	3	4	-	-	PUNCT
admet-839	3	5	415	415	NUM
admet-839	3	6	-	-	PUNCT
admet-839	3	7	9204	9204	NUM
admet-839	3	8	received	receive	VERB
admet-839	3	9	:	:	PUNCT
admet-839	3	10	may	may	AUX
admet-839	3	11	01	01	NUM
admet-839	3	12	,	,	PUNCT
admet-839	3	13	2020	2020	NUM
admet-839	3	14	;	;	PUNCT
admet-839	3	15	revised	revise	VERB
admet-839	3	16	:	:	PUNCT
admet-839	3	17	july	july	PROPN
admet-839	3	18	10	10	NUM
admet-839	3	19	,	,	PUNCT
admet-839	3	20	2020	2020	NUM
admet-839	3	21	;	;	PUNCT
admet-839	3	22	published	publish	VERB
admet-839	3	23	:	:	PUNCT
admet-839	3	24	july	july	PROPN
admet-839	3	25	13	13	NUM
admet-839	3	26	,	,	PUNCT
admet-839	3	27	2020	2020	NUM
admet-839	3	28	abstract	abstract	ADJ
admet-839	3	29	poor	poor	ADJ
admet-839	3	30	solubility	solubility	NOUN
admet-839	3	31	of	of	ADP
admet-839	3	32	crystalline	crystalline	ADJ
admet-839	3	33	drugs	drug	NOUN
admet-839	3	34	can	can	AUX
admet-839	3	35	be	be	AUX
admet-839	3	36	overcome	overcome	VERB
admet-839	3	37	by	by	ADP
admet-839	3	38	amorphization	amorphization	NOUN
admet-839	3	39	–	–	PUNCT
admet-839	3	40	the	the	DET
admet-839	3	41	production	production	NOUN
admet-839	3	42	of	of	ADP
admet-839	3	43	high	high	ADJ
admet-839	3	44	-	-	PUNCT
admet-839	3	45	energy	energy	NOUN
admet-839	3	46	disordered	disorder	VERB
admet-839	3	47	solid	solid	ADJ
admet-839	3	48	with	with	ADP
admet-839	3	49	improved	improved	ADJ
admet-839	3	50	solubility	solubility	NOUN
admet-839	3	51	.	.	PUNCT
admet-839	4	1	however	however	ADV
admet-839	4	2	,	,	PUNCT
admet-839	4	3	the	the	DET
admet-839	4	4	improved	improved	ADJ
admet-839	4	5	solubility	solubility	NOUN
admet-839	4	6	comes	come	VERB
admet-839	4	7	at	at	ADP
admet-839	4	8	a	a	DET
admet-839	4	9	cost	cost	NOUN
admet-839	4	10	of	of	ADP
admet-839	4	11	reduced	reduced	ADJ
admet-839	4	12	stability	stability	NOUN
admet-839	4	13	;	;	PUNCT
admet-839	4	14	amorphous	amorphous	ADJ
admet-839	4	15	drugs	drug	NOUN
admet-839	4	16	are	be	AUX
admet-839	4	17	prone	prone	ADJ
admet-839	4	18	to	to	ADP
admet-839	4	19	recrystallization	recrystallization	NOUN
admet-839	4	20	.	.	PUNCT
admet-839	5	1	because	because	SCONJ
admet-839	5	2	of	of	ADP
admet-839	5	3	recrystallization	recrystallization	NOUN
admet-839	5	4	,	,	PUNCT
admet-839	5	5	the	the	DET
admet-839	5	6	initial	initial	ADJ
admet-839	5	7	solubility	solubility	NOUN
admet-839	5	8	enhancement	enhancement	NOUN
admet-839	5	9	is	be	AUX
admet-839	5	10	eventually	eventually	ADV
admet-839	5	11	lost	lose	VERB
admet-839	5	12	.	.	PUNCT
admet-839	6	1	therefore	therefore	ADV
admet-839	6	2	,	,	PUNCT
admet-839	6	3	it	it	PRON
admet-839	6	4	is	be	AUX
admet-839	6	5	important	important	ADJ
admet-839	6	6	to	to	PART
admet-839	6	7	understand	understand	VERB
admet-839	6	8	the	the	DET
admet-839	6	9	recrystallization	recrystallization	NOUN
admet-839	6	10	process	process	NOUN
admet-839	6	11	during	during	ADP
admet-839	6	12	storage	storage	NOUN
admet-839	6	13	of	of	ADP
admet-839	6	14	amorphous	amorphous	ADJ
admet-839	6	15	materials	material	NOUN
admet-839	6	16	and	and	CCONJ
admet-839	6	17	its	its	PRON
admet-839	6	18	impact	impact	NOUN
admet-839	6	19	on	on	ADP
admet-839	6	20	dissolution	dissolution	PROPN
admet-839	6	21	/	/	SYM
admet-839	6	22	solubility	solubility	PROPN
admet-839	6	23	.	.	PUNCT
admet-839	7	1	here	here	ADV
admet-839	7	2	,	,	PUNCT
admet-839	7	3	we	we	PRON
admet-839	7	4	demonstrate	demonstrate	VERB
admet-839	7	5	the	the	DET
admet-839	7	6	use	use	NOUN
admet-839	7	7	of	of	ADP
admet-839	7	8	image	image	NOUN
admet-839	7	9	-	-	PUNCT
admet-839	7	10	based	base	VERB
admet-839	7	11	single	single	ADJ
admet-839	7	12	-	-	PUNCT
admet-839	7	13	particle	particle	NOUN
admet-839	7	14	analysis	analysis	NOUN
admet-839	7	15	(	(	PUNCT
admet-839	7	16	spa	spa	NOUN
admet-839	7	17	)	)	PUNCT
admet-839	7	18	to	to	PART
admet-839	7	19	consistently	consistently	ADV
admet-839	7	20	monitor	monitor	VERB
admet-839	7	21	the	the	DET
admet-839	7	22	solubility	solubility	NOUN
admet-839	7	23	of	of	ADP
admet-839	7	24	an	an	DET
admet-839	7	25	amorphous	amorphous	ADJ
admet-839	7	26	indomethacin	indomethacin	NOUN
admet-839	7	27	sample	sample	NOUN
admet-839	7	28	over	over	ADP
admet-839	7	29	time	time	NOUN
admet-839	7	30	.	.	PUNCT
admet-839	8	1	the	the	DET
admet-839	8	2	results	result	NOUN
admet-839	8	3	are	be	AUX
admet-839	8	4	compared	compare	VERB
admet-839	8	5	to	to	ADP
admet-839	8	6	the	the	DET
admet-839	8	7	xrpd	xrpd	PROPN
admet-839	8	8	signal	signal	NOUN
admet-839	8	9	of	of	ADP
admet-839	8	10	the	the	DET
admet-839	8	11	same	same	ADJ
admet-839	8	12	sample	sample	NOUN
admet-839	8	13	.	.	PUNCT
admet-839	9	1	for	for	SCONJ
admet-839	9	2	the	the	DET
admet-839	9	3	sample	sample	NOUN
admet-839	9	4	stored	store	VERB
admet-839	9	5	at	at	ADP
admet-839	9	6	22	22	NUM
admet-839	9	7	°	°	NUM
admet-839	9	8	c/23	c/23	ADJ
admet-839	9	9	%	%	NOUN
admet-839	9	10	relative	relative	ADJ
admet-839	9	11	humidity	humidity	NOUN
admet-839	9	12	(	(	PUNCT
admet-839	9	13	rh	rh	PROPN
admet-839	9	14	)	)	PUNCT
admet-839	9	15	,	,	PUNCT
admet-839	9	16	full	full	ADJ
admet-839	9	17	crystallinity	crystallinity	NOUN
admet-839	9	18	as	as	SCONJ
admet-839	9	19	indicated	indicate	VERB
admet-839	9	20	by	by	ADP
admet-839	9	21	xrpd	xrpd	PROPN
admet-839	9	22	was	be	AUX
admet-839	9	23	reached	reach	VERB
admet-839	9	24	around	around	ADP
admet-839	9	25	day	day	NOUN
admet-839	9	26	40	40	NUM
admet-839	9	27	,	,	PUNCT
admet-839	9	28	whereas	whereas	SCONJ
admet-839	9	29	a	a	DET
admet-839	9	30	solubility	solubility	NOUN
admet-839	9	31	corresponding	correspond	VERB
admet-839	9	32	to	to	ADP
admet-839	9	33	that	that	PRON
admet-839	9	34	of	of	ADP
admet-839	9	35	the	the	DET
admet-839	9	36	γ	γ	PROPN
admet-839	9	37	crystalline	crystalline	NOUN
admet-839	9	38	form	form	NOUN
admet-839	9	39	was	be	AUX
admet-839	9	40	measured	measure	VERB
admet-839	9	41	with	with	ADP
admet-839	9	42	spa	spa	NOUN
admet-839	9	43	at	at	ADP
admet-839	9	44	day	day	NOUN
admet-839	9	45	25	25	NUM
admet-839	9	46	.	.	PUNCT
admet-839	10	1	for	for	ADP
admet-839	10	2	the	the	DET
admet-839	10	3	sample	sample	NOUN
admet-839	10	4	stored	store	VERB
admet-839	10	5	at	at	ADP
admet-839	10	6	22	22	NUM
admet-839	10	7	°	°	NUM
admet-839	10	8	c/75	c/75	PROPN
admet-839	10	9	%	%	NOUN
admet-839	10	10	rh	rh	PROPN
admet-839	10	11	,	,	PUNCT
admet-839	10	12	the	the	DET
admet-839	10	13	xrpd	xrpd	PROPN
admet-839	10	14	signal	signal	PROPN
admet-839	10	15	indicated	indicate	VERB
admet-839	10	16	a	a	DET
admet-839	10	17	rapid	rapid	ADJ
admet-839	10	18	initial	initial	ADJ
admet-839	10	19	phase	phase	NOUN
admet-839	10	20	of	of	ADP
admet-839	10	21	crystallization	crystallization	NOUN
admet-839	10	22	.	.	PUNCT
admet-839	11	1	however	however	ADV
admet-839	11	2	,	,	PUNCT
admet-839	11	3	the	the	DET
admet-839	11	4	sample	sample	NOUN
admet-839	11	5	failed	fail	VERB
admet-839	11	6	to	to	PART
admet-839	11	7	fully	fully	ADV
admet-839	11	8	crystallize	crystallize	VERB
admet-839	11	9	in	in	ADP
admet-839	11	10	80	80	NUM
admet-839	11	11	days	day	NOUN
admet-839	11	12	.	.	PUNCT
admet-839	12	1	with	with	ADP
admet-839	12	2	spa	spa	NOUN
admet-839	12	3	,	,	PUNCT
admet-839	12	4	solubility	solubility	NOUN
admet-839	12	5	slightly	slightly	ADV
admet-839	12	6	above	above	ADP
admet-839	12	7	that	that	PRON
admet-839	12	8	of	of	ADP
admet-839	12	9	the	the	DET
admet-839	12	10	crystalline	crystalline	NOUN
admet-839	12	11	γ	γ	PROPN
admet-839	12	12	form	form	NOUN
admet-839	12	13	was	be	AUX
admet-839	12	14	measured	measure	VERB
admet-839	12	15	already	already	ADV
admet-839	12	16	on	on	ADP
admet-839	12	17	the	the	DET
admet-839	12	18	second	second	ADJ
admet-839	12	19	day	day	NOUN
admet-839	12	20	.	.	PUNCT
admet-839	13	1	to	to	PART
admet-839	13	2	conclude	conclude	VERB
admet-839	13	3	,	,	PUNCT
admet-839	13	4	the	the	DET
admet-839	13	5	solubility	solubility	NOUN
admet-839	13	6	measured	measure	VERB
admet-839	13	7	with	with	ADP
admet-839	13	8	spa	spa	NOUN
admet-839	13	9	directly	directly	ADV
admet-839	13	10	reflects	reflect	VERB
admet-839	13	11	the	the	DET
admet-839	13	12	solid	solid	ADJ
admet-839	13	13	-	-	PUNCT
admet-839	13	14	state	state	NOUN
admet-839	13	15	changes	change	NOUN
admet-839	13	16	occurring	occur	VERB
admet-839	13	17	on	on	ADP
admet-839	13	18	the	the	DET
admet-839	13	19	particle	particle	NOUN
admet-839	13	20	surface	surface	NOUN
admet-839	13	21	.	.	PUNCT
admet-839	14	1	therefore	therefore	ADV
admet-839	14	2	,	,	PUNCT
admet-839	14	3	it	it	PRON
admet-839	14	4	can	can	AUX
admet-839	14	5	provide	provide	VERB
admet-839	14	6	vital	vital	ADJ
admet-839	14	7	information	information	NOUN
admet-839	14	8	–	–	PUNCT
admet-839	14	9	in	in	ADP
admet-839	14	10	a	a	DET
admet-839	14	11	straightforward	straightforward	ADJ
admet-839	14	12	manner	manner	NOUN
admet-839	14	13	while	while	SCONJ
admet-839	14	14	requiring	require	VERB
admet-839	14	15	only	only	ADJ
admet-839	14	16	minuscule	minuscule	ADJ
admet-839	14	17	sample	sample	NOUN
admet-839	14	18	amounts	amount	NOUN
admet-839	14	19	–	–	PUNCT
admet-839	14	20	for	for	ADP
admet-839	14	21	understanding	understand	VERB
admet-839	14	22	the	the	DET
admet-839	14	23	effect	effect	NOUN
admet-839	14	24	of	of	ADP
admet-839	14	25	storage	storage	NOUN
admet-839	14	26	conditions	condition	NOUN
admet-839	14	27	on	on	ADP
admet-839	14	28	the	the	DET
admet-839	14	29	dissolution	dissolution	NOUN
admet-839	14	30	/	/	SYM
admet-839	14	31	solubility	solubility	NOUN
admet-839	14	32	of	of	ADP
admet-839	14	33	amorphous	amorphous	ADJ
admet-839	14	34	materials	material	NOUN
admet-839	14	35	,	,	PUNCT
admet-839	14	36	especially	especially	ADV
admet-839	14	37	important	important	ADJ
admet-839	14	38	in	in	ADP
admet-839	14	39	pharmaceutical	pharmaceutical	ADJ
admet-839	14	40	science	science	NOUN
admet-839	14	41	.	.	PUNCT
admet-839	15	1	©	©	PROPN
admet-839	15	2	2020	2020	NUM
admet-839	15	3	by	by	ADP
admet-839	15	4	the	the	DET
admet-839	15	5	authors	author	NOUN
admet-839	15	6	.	.	PUNCT
admet-839	16	1	this	this	DET
admet-839	16	2	article	article	NOUN
admet-839	16	3	is	be	AUX
admet-839	16	4	an	an	DET
admet-839	16	5	open	open	ADJ
admet-839	16	6	-	-	PUNCT
admet-839	16	7	access	access	NOUN
admet-839	16	8	article	article	NOUN
admet-839	16	9	distributed	distribute	VERB
admet-839	16	10	under	under	ADP
admet-839	16	11	the	the	DET
admet-839	16	12	terms	term	NOUN
admet-839	16	13	and	and	CCONJ
admet-839	16	14	conditions	condition	NOUN
admet-839	16	15	of	of	ADP
admet-839	16	16	the	the	DET
admet-839	16	17	creative	creative	ADJ
admet-839	16	18	commons	common	NOUN
admet-839	16	19	attribution	attribution	NOUN
admet-839	16	20	license	license	NOUN
admet-839	16	21	(	(	PUNCT
admet-839	16	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-839	16	23	)	)	PUNCT
admet-839	16	24	.	.	PUNCT
admet-839	17	1	keywords	keyword	VERB
admet-839	17	2	solubility	solubility	NOUN
admet-839	17	3	;	;	PUNCT
admet-839	17	4	stability	stability	NOUN
admet-839	17	5	;	;	PUNCT
admet-839	17	6	crystallization	crystallization	NOUN
admet-839	17	7	;	;	PUNCT
admet-839	17	8	amorphous	amorphous	ADJ
admet-839	17	9	;	;	PUNCT
admet-839	17	10	single	single	ADJ
admet-839	17	11	-	-	PUNCT
admet-839	17	12	particle	particle	NOUN
admet-839	17	13	analysis	analysis	NOUN
admet-839	17	14	;	;	PUNCT
admet-839	17	15	spa	spa	NOUN
admet-839	17	16	introduction	introduction	NOUN
admet-839	17	17	in	in	ADP
admet-839	17	18	pharmaceutical	pharmaceutical	ADJ
admet-839	17	19	industry	industry	NOUN
admet-839	17	20	,	,	PUNCT
admet-839	17	21	solid	solid	ADJ
admet-839	17	22	-	-	PUNCT
admet-839	17	23	state	state	NOUN
admet-839	17	24	form	form	NOUN
admet-839	17	25	selection	selection	NOUN
admet-839	17	26	of	of	ADP
admet-839	17	27	an	an	DET
admet-839	17	28	active	active	ADJ
admet-839	17	29	pharmaceutical	pharmaceutical	ADJ
admet-839	17	30	ingredient	ingredient	NOUN
admet-839	17	31	(	(	PUNCT
admet-839	17	32	api	api	NOUN
admet-839	17	33	)	)	PUNCT
admet-839	17	34	is	be	AUX
admet-839	17	35	an	an	DET
admet-839	17	36	important	important	ADJ
admet-839	17	37	step	step	NOUN
admet-839	17	38	in	in	ADP
admet-839	17	39	the	the	DET
admet-839	17	40	development	development	NOUN
admet-839	17	41	of	of	ADP
admet-839	17	42	a	a	DET
admet-839	17	43	solid	solid	ADJ
admet-839	17	44	dosage	dosage	NOUN
admet-839	17	45	form	form	NOUN
admet-839	17	46	.	.	PUNCT
admet-839	18	1	the	the	DET
admet-839	18	2	solid	solid	ADJ
admet-839	18	3	-	-	PUNCT
admet-839	18	4	state	state	NOUN
admet-839	18	5	form	form	NOUN
admet-839	18	6	governs	govern	VERB
admet-839	18	7	the	the	DET
admet-839	18	8	processability	processability	NOUN
admet-839	18	9	,	,	PUNCT
admet-839	18	10	stability	stability	NOUN
admet-839	18	11	and	and	CCONJ
admet-839	18	12	bioavailability	bioavailability	NOUN
admet-839	18	13	of	of	ADP
admet-839	18	14	the	the	DET
admet-839	18	15	final	final	ADJ
admet-839	18	16	product	product	NOUN
admet-839	18	17	.	.	PUNCT
admet-839	19	1	thus	thus	ADV
admet-839	19	2	,	,	PUNCT
admet-839	19	3	poorly	poorly	ADV
admet-839	19	4	soluble	soluble	ADJ
admet-839	19	5	crystalline	crystalline	NOUN
admet-839	19	6	apis	apis	NOUN
admet-839	19	7	can	can	AUX
admet-839	19	8	be	be	AUX
admet-839	19	9	replaced	replace	VERB
admet-839	19	10	by	by	ADP
admet-839	19	11	their	their	PRON
admet-839	19	12	respective	respective	ADJ
admet-839	19	13	,	,	PUNCT
admet-839	19	14	more	more	ADV
admet-839	19	15	soluble	soluble	ADJ
admet-839	19	16	,	,	PUNCT
admet-839	19	17	amorphous	amorphous	ADJ
admet-839	19	18	forms	form	NOUN
admet-839	19	19	[	[	X
admet-839	19	20	1	1	NUM
admet-839	19	21	-	-	SYM
admet-839	19	22	3	3	NUM
admet-839	19	23	]	]	PUNCT
admet-839	19	24	.	.	PUNCT
admet-839	20	1	however	however	ADV
admet-839	20	2	,	,	PUNCT
admet-839	20	3	an	an	DET
admet-839	20	4	increase	increase	NOUN
admet-839	20	5	in	in	ADP
admet-839	20	6	apparent	apparent	ADJ
admet-839	20	7	solubility	solubility	NOUN
admet-839	20	8	,	,	PUNCT
admet-839	20	9	and	and	CCONJ
admet-839	20	10	consequently	consequently	ADV
admet-839	20	11	bioavailability	bioavailability	NOUN
admet-839	20	12	,	,	PUNCT
admet-839	20	13	comes	come	VERB
admet-839	20	14	at	at	ADP
admet-839	20	15	a	a	DET
admet-839	20	16	price	price	NOUN
admet-839	20	17	of	of	ADP
admet-839	20	18	instability	instability	NOUN
admet-839	20	19	.	.	PUNCT
admet-839	21	1	therefore	therefore	ADV
admet-839	21	2	,	,	PUNCT
admet-839	21	3	monitoring	monitoring	NOUN
admet-839	21	4	and	and	CCONJ
admet-839	21	5	understanding	understanding	NOUN
admet-839	21	6	of	of	ADP
admet-839	21	7	amorphous	amorphous	ADJ
admet-839	21	8	form	form	NOUN
admet-839	21	9	instability	instability	NOUN
admet-839	21	10	–	–	PUNCT
admet-839	21	11	recrystallization	recrystallization	NOUN
admet-839	21	12	–	–	PUNCT
admet-839	21	13	is	be	AUX
admet-839	21	14	crucial	crucial	ADJ
admet-839	21	15	for	for	ADP
admet-839	21	16	optimal	optimal	ADJ
admet-839	21	17	product	product	NOUN
admet-839	21	18	design	design	NOUN
admet-839	21	19	.	.	PUNCT
admet-839	22	1	http://dx.doi.org/10.5599/admet.839	http://dx.doi.org/10.5599/admet.839	PROPN
admet-839	22	2	https://doi.org/10.5599/admet.839	https://doi.org/10.5599/admet.839	VERB
admet-839	23	1	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-839	23	2	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-839	23	3	jernej	jernej	PROPN
admet-839	23	4	štukelj	štukelj	PROPN
admet-839	23	5	et	et	PROPN
admet-839	23	6	al	al	PROPN
admet-839	23	7	.	.	PROPN
admet-839	23	8	admet	admet	PROPN
admet-839	23	9	&	&	CCONJ
admet-839	23	10	dmpk	dmpk	PROPN
admet-839	23	11	8(4	8(4	NOUN
admet-839	23	12	)	)	PUNCT
admet-839	23	13	(	(	PUNCT
admet-839	23	14	2020	2020	NUM
admet-839	23	15	)	)	PUNCT
admet-839	23	16	401	401	NUM
admet-839	23	17	-	-	SYM
admet-839	23	18	409	409	NUM
admet-839	23	19	402	402	NUM
admet-839	23	20	the	the	DET
admet-839	23	21	non	non	ADJ
admet-839	23	22	-	-	ADJ
admet-839	23	23	steroidal	steroidal	ADJ
admet-839	23	24	-	-	PUNCT
admet-839	23	25	anti	anti	ADJ
admet-839	23	26	-	-	ADJ
admet-839	23	27	inflammatory	inflammatory	ADJ
admet-839	23	28	drug	drug	NOUN
admet-839	23	29	indomethacin	indomethacin	NOUN
admet-839	23	30	has	have	AUX
admet-839	23	31	been	be	AUX
admet-839	23	32	widely	widely	ADV
admet-839	23	33	used	use	VERB
admet-839	23	34	as	as	ADP
admet-839	23	35	model	model	NOUN
admet-839	23	36	drug	drug	NOUN
admet-839	23	37	to	to	PART
admet-839	23	38	study	study	VERB
admet-839	23	39	recrystallization	recrystallization	NOUN
admet-839	23	40	behaviour	behaviour	NOUN
admet-839	23	41	with	with	ADP
admet-839	23	42	the	the	DET
admet-839	23	43	first	first	ADJ
admet-839	23	44	studies	study	NOUN
admet-839	23	45	dating	date	VERB
admet-839	23	46	all	all	DET
admet-839	23	47	the	the	DET
admet-839	23	48	way	way	NOUN
admet-839	23	49	back	back	ADV
admet-839	23	50	to	to	ADP
admet-839	23	51	the	the	DET
admet-839	23	52	1970s	1970	NOUN
admet-839	24	1	[	[	X
admet-839	24	2	4,5	4,5	NUM
admet-839	24	3	]	]	PUNCT
admet-839	24	4	.	.	PUNCT
admet-839	25	1	stability	stability	NOUN
admet-839	25	2	studies	study	NOUN
admet-839	25	3	looking	look	VERB
admet-839	25	4	at	at	ADP
admet-839	25	5	amorphous	amorphous	ADJ
admet-839	25	6	indomethacin	indomethacin	NOUN
admet-839	25	7	can	can	AUX
admet-839	25	8	be	be	AUX
admet-839	25	9	divided	divide	VERB
admet-839	25	10	in	in	ADP
admet-839	25	11	two	two	NUM
admet-839	25	12	groups	group	NOUN
admet-839	25	13	:	:	PUNCT
admet-839	25	14	amorphous	amorphous	ADJ
admet-839	25	15	stability	stability	NOUN
admet-839	25	16	during	during	ADP
admet-839	25	17	storage	storage	NOUN
admet-839	25	18	and	and	CCONJ
admet-839	25	19	amorphous	amorphous	ADJ
admet-839	25	20	stability	stability	NOUN
admet-839	25	21	during	during	ADP
admet-839	25	22	dissolution	dissolution	ADJ
admet-839	25	23	testing	testing	NOUN
admet-839	25	24	.	.	PUNCT
admet-839	26	1	the	the	DET
admet-839	26	2	behaviour	behaviour	NOUN
admet-839	26	3	of	of	ADP
admet-839	26	4	amorphous	amorphous	ADJ
admet-839	26	5	indomethacin	indomethacin	NOUN
admet-839	26	6	during	during	ADP
admet-839	26	7	storage	storage	NOUN
admet-839	26	8	is	be	AUX
admet-839	26	9	governed	govern	VERB
admet-839	26	10	by	by	ADP
admet-839	26	11	temperature	temperature	NOUN
admet-839	26	12	and	and	CCONJ
admet-839	26	13	humidity	humidity	NOUN
admet-839	26	14	[	[	X
admet-839	26	15	6	6	NUM
admet-839	26	16	–	–	PUNCT
admet-839	26	17	8	8	NUM
admet-839	26	18	]	]	PUNCT
admet-839	26	19	.	.	PUNCT
admet-839	27	1	the	the	DET
admet-839	27	2	two	two	NUM
admet-839	27	3	parameters	parameter	NOUN
admet-839	27	4	determine	determine	VERB
admet-839	27	5	the	the	DET
admet-839	27	6	direction	direction	NOUN
admet-839	27	7	of	of	ADP
admet-839	27	8	crystallization	crystallization	NOUN
admet-839	27	9	of	of	ADP
admet-839	27	10	amorphous	amorphous	ADJ
admet-839	27	11	indomethacin	indomethacin	NOUN
admet-839	27	12	prepared	prepare	VERB
admet-839	27	13	by	by	ADP
admet-839	27	14	cooling	cool	VERB
admet-839	27	15	the	the	DET
admet-839	27	16	melt	melt	NOUN
admet-839	27	17	;	;	PUNCT
admet-839	27	18	at	at	ADP
admet-839	27	19	30	30	NUM
admet-839	27	20	°	°	NOUN
admet-839	27	21	c	c	NOUN
admet-839	27	22	,	,	PUNCT
admet-839	27	23	the	the	DET
admet-839	27	24	metastable	metastable	ADJ
admet-839	27	25	α	α	PROPN
admet-839	27	26	form	form	NOUN
admet-839	27	27	predominantly	predominantly	ADV
admet-839	27	28	crystallizes	crystallize	VERB
admet-839	27	29	at	at	ADP
admet-839	27	30	high	high	ADJ
admet-839	27	31	humidity	humidity	NOUN
admet-839	27	32	(	(	PUNCT
admet-839	27	33	>	>	SYM
admet-839	27	34	56	56	NUM
admet-839	27	35	%	%	NOUN
admet-839	27	36	relative	relative	ADJ
admet-839	27	37	humidity	humidity	NOUN
admet-839	27	38	(	(	PUNCT
admet-839	27	39	rh	rh	PROPN
admet-839	27	40	)	)	PUNCT
admet-839	27	41	)	)	PUNCT
admet-839	28	1	and	and	CCONJ
admet-839	28	2	the	the	DET
admet-839	28	3	thermodynamically	thermodynamically	ADV
admet-839	28	4	stable	stable	ADJ
admet-839	28	5	γ	γ	PROPN
admet-839	28	6	form	form	NOUN
admet-839	28	7	predominantly	predominantly	ADV
admet-839	28	8	crystallizes	crystallize	VERB
admet-839	28	9	at	at	ADP
admet-839	28	10	low	low	ADJ
admet-839	28	11	humidity	humidity	NOUN
admet-839	28	12	(	(	PUNCT
admet-839	28	13	<	<	X
admet-839	28	14	43	43	NUM
admet-839	28	15	%	%	NOUN
admet-839	28	16	rh	rh	PROPN
admet-839	28	17	)	)	PUNCT
admet-839	29	1	[	[	X
admet-839	29	2	6	6	NUM
admet-839	29	3	]	]	PUNCT
admet-839	29	4	.	.	PUNCT
admet-839	30	1	water	water	NOUN
admet-839	30	2	acts	act	VERB
admet-839	30	3	as	as	ADP
admet-839	30	4	a	a	DET
admet-839	30	5	plasticizer	plasticizer	NOUN
admet-839	30	6	and	and	CCONJ
admet-839	30	7	thus	thus	ADV
admet-839	30	8	,	,	PUNCT
admet-839	30	9	with	with	ADP
admet-839	30	10	an	an	DET
admet-839	30	11	increase	increase	NOUN
admet-839	30	12	in	in	ADP
admet-839	30	13	humidity	humidity	NOUN
admet-839	30	14	,	,	PUNCT
admet-839	30	15	the	the	DET
admet-839	30	16	glass	glass	NOUN
admet-839	30	17	transition	transition	NOUN
admet-839	30	18	(	(	PUNCT
admet-839	30	19	tg	tg	PROPN
admet-839	30	20	)	)	PUNCT
admet-839	30	21	of	of	ADP
admet-839	30	22	amorphous	amorphous	ADJ
admet-839	30	23	indomethacin	indomethacin	NOUN
admet-839	30	24	decreases	decrease	NOUN
admet-839	30	25	.	.	PUNCT
admet-839	31	1	temperatures	temperature	NOUN
admet-839	31	2	below	below	ADP
admet-839	31	3	the	the	DET
admet-839	31	4	tg	tg	PROPN
admet-839	31	5	favour	favour	NOUN
admet-839	31	6	formation	formation	NOUN
admet-839	31	7	of	of	ADP
admet-839	31	8	the	the	DET
admet-839	31	9	γ	γ	NOUN
admet-839	31	10	form	form	NOUN
admet-839	31	11	and	and	CCONJ
admet-839	31	12	temperatures	temperature	NOUN
admet-839	31	13	above	above	ADP
admet-839	31	14	tg	tg	PROPN
admet-839	31	15	favour	favour	ADJ
admet-839	31	16	formation	formation	NOUN
admet-839	31	17	of	of	ADP
admet-839	31	18	the	the	DET
admet-839	31	19	α	α	NOUN
admet-839	31	20	form	form	NOUN
admet-839	31	21	.	.	PUNCT
admet-839	32	1	furthermore	furthermore	ADV
admet-839	32	2	,	,	PUNCT
admet-839	32	3	crystallization	crystallization	NOUN
admet-839	32	4	may	may	AUX
admet-839	32	5	also	also	ADV
admet-839	32	6	be	be	AUX
admet-839	32	7	considered	consider	VERB
admet-839	32	8	from	from	ADP
admet-839	32	9	a	a	DET
admet-839	32	10	surface	surface	NOUN
admet-839	32	11	versus	versus	ADP
admet-839	32	12	bulk	bulk	ADJ
admet-839	32	13	perspective	perspective	NOUN
admet-839	32	14	:	:	PUNCT
admet-839	32	15	for	for	ADP
admet-839	32	16	quench	quench	NOUN
admet-839	32	17	-	-	PUNCT
admet-839	32	18	cooled	cool	VERB
admet-839	32	19	amorphous	amorphous	ADJ
admet-839	32	20	films	film	NOUN
admet-839	32	21	,	,	PUNCT
admet-839	32	22	v.	v.	ADP
admet-839	32	23	andronis	andronis	PROPN
admet-839	32	24	et	et	PROPN
admet-839	32	25	al	al	PROPN
admet-839	32	26	.	.	PROPN
admet-839	32	27	reported	report	VERB
admet-839	32	28	30	30	NUM
admet-839	32	29	°	°	NUM
admet-839	32	30	c/11	c/11	PROPN
admet-839	32	31	%	%	NOUN
admet-839	32	32	rh	rh	PROPN
admet-839	32	33	as	as	ADP
admet-839	32	34	a	a	DET
admet-839	32	35	limit	limit	NOUN
admet-839	32	36	below	below	ADP
admet-839	32	37	which	which	DET
admet-839	32	38	crystallization	crystallization	NOUN
admet-839	32	39	was	be	AUX
admet-839	32	40	surface	surface	NOUN
admet-839	32	41	-	-	PUNCT
admet-839	32	42	initiated	initiate	VERB
admet-839	32	43	and	and	CCONJ
admet-839	32	44	30	30	NUM
admet-839	32	45	°	°	NUM
admet-839	32	46	c/21	c/21	NOUN
admet-839	32	47	%	%	NOUN
admet-839	32	48	rh	rh	PROPN
admet-839	32	49	as	as	ADP
admet-839	32	50	a	a	DET
admet-839	32	51	limit	limit	NOUN
admet-839	32	52	above	above	ADP
admet-839	32	53	which	which	DET
admet-839	32	54	crystallization	crystallization	NOUN
admet-839	32	55	was	be	AUX
admet-839	32	56	bulk	bulk	NOUN
admet-839	32	57	-	-	PUNCT
admet-839	32	58	initiated	initiate	VERB
admet-839	32	59	[	[	X
admet-839	32	60	6	6	NUM
admet-839	32	61	]	]	PUNCT
admet-839	32	62	.	.	PUNCT
admet-839	33	1	in	in	ADP
admet-839	33	2	addition	addition	NOUN
admet-839	33	3	,	,	PUNCT
admet-839	33	4	wu	wu	PROPN
admet-839	33	5	et	et	PROPN
admet-839	33	6	al	al	PROPN
admet-839	33	7	.	.	PROPN
admet-839	33	8	reported	report	VERB
admet-839	33	9	surface	surface	NOUN
admet-839	33	10	crystallization	crystallization	NOUN
admet-839	33	11	being	be	AUX
admet-839	33	12	two	two	NUM
admet-839	33	13	orders	order	NOUN
admet-839	33	14	of	of	ADP
admet-839	33	15	magnitude	magnitude	NOUN
admet-839	33	16	higher	high	ADJ
admet-839	33	17	compared	compare	VERB
admet-839	33	18	to	to	ADP
admet-839	33	19	bulk	bulk	ADJ
admet-839	33	20	crystallization	crystallization	NOUN
admet-839	33	21	for	for	ADP
admet-839	33	22	amorphous	amorphous	ADJ
admet-839	33	23	films	film	NOUN
admet-839	33	24	stored	store	VERB
admet-839	33	25	at	at	ADP
admet-839	33	26	40	40	NUM
admet-839	33	27	°	°	NOUN
admet-839	33	28	c	c	NOUN
admet-839	33	29	[	[	X
admet-839	33	30	8	8	NUM
admet-839	33	31	]	]	PUNCT
admet-839	33	32	.	.	PUNCT
admet-839	34	1	when	when	SCONJ
admet-839	34	2	exposed	expose	VERB
admet-839	34	3	to	to	ADP
admet-839	34	4	dissolution	dissolution	NOUN
admet-839	34	5	medium	medium	NOUN
admet-839	34	6	,	,	PUNCT
admet-839	34	7	the	the	DET
admet-839	34	8	amorphous	amorphous	ADJ
admet-839	34	9	solid	solid	ADJ
admet-839	34	10	undergoes	undergoe	NOUN
admet-839	34	11	solid	solid	ADJ
admet-839	34	12	-	-	PUNCT
admet-839	34	13	state	state	NOUN
admet-839	34	14	transformation	transformation	NOUN
admet-839	34	15	via	via	ADP
admet-839	34	16	two	two	NUM
admet-839	34	17	pathways	pathway	NOUN
admet-839	34	18	:	:	PUNCT
admet-839	34	19	a	a	DET
admet-839	34	20	direct	direct	ADJ
admet-839	34	21	recrystallization	recrystallization	NOUN
admet-839	34	22	of	of	ADP
admet-839	34	23	the	the	DET
admet-839	34	24	solid	solid	ADJ
admet-839	34	25	and/or	and/or	CCONJ
admet-839	34	26	a	a	DET
admet-839	34	27	solution	solution	NOUN
admet-839	34	28	mediated	mediate	VERB
admet-839	34	29	crystallization	crystallization	NOUN
admet-839	34	30	from	from	ADP
admet-839	34	31	the	the	DET
admet-839	34	32	supersaturated	supersaturated	ADJ
admet-839	34	33	solution	solution	NOUN
admet-839	34	34	[	[	X
admet-839	34	35	9	9	NUM
admet-839	34	36	]	]	PUNCT
admet-839	34	37	.	.	PUNCT
admet-839	35	1	d.	d.	PROPN
admet-839	35	2	alonzo	alonzo	PROPN
admet-839	35	3	et	et	PROPN
admet-839	35	4	al	al	PROPN
admet-839	35	5	.	.	PROPN
admet-839	35	6	reported	report	VERB
admet-839	35	7	that	that	SCONJ
admet-839	35	8	crystallization	crystallization	NOUN
admet-839	35	9	from	from	ADP
admet-839	35	10	supersaturated	supersaturated	ADJ
admet-839	35	11	solution	solution	NOUN
admet-839	35	12	was	be	AUX
admet-839	35	13	the	the	DET
admet-839	35	14	main	main	ADJ
admet-839	35	15	mechanism	mechanism	NOUN
admet-839	35	16	reducing	reduce	VERB
admet-839	35	17	the	the	DET
admet-839	35	18	solubility	solubility	NOUN
admet-839	35	19	of	of	ADP
admet-839	35	20	amorphous	amorphous	ADJ
admet-839	35	21	indomethacin	indomethacin	NOUN
admet-839	35	22	.	.	PUNCT
admet-839	36	1	however	however	ADV
admet-839	36	2	,	,	PUNCT
admet-839	36	3	the	the	DET
admet-839	36	4	adsorption	adsorption	NOUN
admet-839	36	5	of	of	ADP
admet-839	36	6	water	water	NOUN
admet-839	36	7	onto	onto	ADP
admet-839	36	8	the	the	DET
admet-839	36	9	exposed	expose	VERB
admet-839	36	10	amorphous	amorphous	ADJ
admet-839	36	11	surface	surface	NOUN
admet-839	36	12	increases	increase	VERB
admet-839	36	13	molecular	molecular	ADJ
admet-839	36	14	mobility	mobility	NOUN
admet-839	36	15	and	and	CCONJ
admet-839	36	16	thus	thus	ADV
admet-839	36	17	potentially	potentially	ADV
admet-839	36	18	promotes	promote	VERB
admet-839	36	19	the	the	DET
admet-839	36	20	surface	surface	NOUN
admet-839	36	21	crystallization	crystallization	NOUN
admet-839	36	22	rate	rate	NOUN
admet-839	36	23	[	[	X
admet-839	36	24	6,10	6,10	X
admet-839	36	25	]	]	PUNCT
admet-839	36	26	.	.	PUNCT
admet-839	37	1	the	the	DET
admet-839	37	2	dissolution	dissolution	PROPN
admet-839	37	3	studies	study	NOUN
admet-839	37	4	in	in	ADP
admet-839	37	5	flow	flow	NOUN
admet-839	37	6	-	-	PUNCT
admet-839	37	7	through	through	ADP
admet-839	37	8	chambers	chamber	NOUN
admet-839	37	9	coupled	couple	VERB
admet-839	37	10	with	with	ADP
admet-839	37	11	raman	raman	NOUN
admet-839	37	12	probes	probe	NOUN
admet-839	37	13	enabled	enable	VERB
admet-839	37	14	the	the	DET
admet-839	37	15	monitoring	monitoring	NOUN
admet-839	37	16	of	of	ADP
admet-839	37	17	dissolution	dissolution	NOUN
admet-839	37	18	rate	rate	NOUN
admet-839	37	19	and	and	CCONJ
admet-839	37	20	crystallization	crystallization	NOUN
admet-839	37	21	,	,	PUNCT
admet-839	37	22	revealing	reveal	VERB
admet-839	37	23	the	the	DET
admet-839	37	24	dependency	dependency	NOUN
admet-839	37	25	of	of	ADP
admet-839	37	26	dissolution	dissolution	ADJ
admet-839	37	27	rate	rate	NOUN
admet-839	37	28	on	on	ADP
admet-839	37	29	processing	process	VERB
admet-839	37	30	history	history	NOUN
admet-839	37	31	of	of	ADP
admet-839	37	32	the	the	DET
admet-839	37	33	amorphous	amorphous	ADJ
admet-839	37	34	solid	solid	ADJ
admet-839	37	35	[	[	X
admet-839	37	36	11,12	11,12	NUM
admet-839	37	37	]	]	PUNCT
admet-839	37	38	.	.	PUNCT
admet-839	38	1	priemel	priemel	X
admet-839	38	2	et	et	PROPN
admet-839	38	3	al	al	PROPN
admet-839	38	4	.	.	PROPN
admet-839	38	5	studied	study	VERB
admet-839	38	6	amorphous	amorphous	ADJ
admet-839	38	7	tablets	tablet	NOUN
admet-839	38	8	stored	store	VERB
admet-839	38	9	at	at	ADP
admet-839	38	10	30	30	NUM
admet-839	38	11	°	°	NUM
admet-839	38	12	c/23	c/23	ADJ
admet-839	38	13	%	%	NOUN
admet-839	38	14	rh	rh	NOUN
admet-839	38	15	with	with	ADP
admet-839	38	16	differential	differential	NOUN
admet-839	38	17	scanning	scanning	NOUN
admet-839	38	18	calorimetry	calorimetry	NOUN
admet-839	38	19	(	(	PUNCT
admet-839	38	20	dsc	dsc	NOUN
admet-839	38	21	)	)	PUNCT
admet-839	38	22	,	,	PUNCT
admet-839	38	23	x	x	X
admet-839	38	24	-	-	NOUN
admet-839	38	25	ray	ray	NOUN
admet-839	38	26	powder	powder	NOUN
admet-839	38	27	diffraction	diffraction	NOUN
admet-839	38	28	(	(	PUNCT
admet-839	38	29	xrpd	xrpd	ADJ
admet-839	38	30	)	)	PUNCT
admet-839	38	31	and	and	CCONJ
admet-839	38	32	fourier	fourier	NOUN
admet-839	38	33	-	-	PUNCT
admet-839	38	34	transform	transform	NOUN
admet-839	38	35	infrared	infrared	NOUN
admet-839	38	36	(	(	PUNCT
admet-839	38	37	ftir	ftir	NOUN
admet-839	38	38	)	)	PUNCT
admet-839	38	39	spectroscopy	spectroscopy	NOUN
admet-839	38	40	and	and	CCONJ
admet-839	38	41	correlated	correlate	VERB
admet-839	38	42	the	the	DET
admet-839	38	43	results	result	NOUN
admet-839	38	44	of	of	ADP
admet-839	38	45	the	the	DET
admet-839	38	46	analytical	analytical	ADJ
admet-839	38	47	techniques	technique	NOUN
admet-839	38	48	to	to	ADP
admet-839	38	49	the	the	DET
admet-839	38	50	dissolution	dissolution	ADJ
admet-839	38	51	performance	performance	NOUN
admet-839	38	52	of	of	ADP
admet-839	38	53	tablets	tablet	NOUN
admet-839	38	54	after	after	ADP
admet-839	38	55	five	five	NUM
admet-839	38	56	days	day	NOUN
admet-839	38	57	of	of	ADP
admet-839	38	58	storage	storage	NOUN
admet-839	38	59	[	[	X
admet-839	38	60	13	13	NUM
admet-839	38	61	]	]	PUNCT
admet-839	38	62	.	.	PUNCT
admet-839	39	1	the	the	DET
admet-839	39	2	dissolution	dissolution	NOUN
admet-839	39	3	is	be	AUX
admet-839	39	4	a	a	DET
admet-839	39	5	purely	purely	ADV
admet-839	39	6	surface	surface	NOUN
admet-839	39	7	phenomenon	phenomenon	NOUN
admet-839	39	8	,	,	PUNCT
admet-839	39	9	and	and	CCONJ
admet-839	39	10	thus	thus	ADV
admet-839	39	11	correlating	correlate	VERB
admet-839	39	12	it	it	PRON
admet-839	39	13	with	with	ADP
admet-839	39	14	the	the	DET
admet-839	39	15	results	result	NOUN
admet-839	39	16	provided	provide	VERB
admet-839	39	17	by	by	ADP
admet-839	39	18	the	the	DET
admet-839	39	19	bulk	bulk	ADJ
admet-839	39	20	analytic	analytic	ADJ
admet-839	39	21	techniques	technique	NOUN
admet-839	39	22	can	can	AUX
admet-839	39	23	be	be	AUX
admet-839	39	24	challenging	challenge	VERB
admet-839	39	25	.	.	PUNCT
admet-839	40	1	novakovic	novakovic	PROPN
admet-839	40	2	et	et	PROPN
admet-839	40	3	al	al	PROPN
admet-839	40	4	.	.	PROPN
admet-839	40	5	employed	employ	VERB
admet-839	40	6	nonlinear	nonlinear	ADJ
admet-839	40	7	optics	optic	NOUN
admet-839	40	8	to	to	PART
admet-839	40	9	study	study	VERB
admet-839	40	10	surface	surface	NOUN
admet-839	40	11	crystallization	crystallization	NOUN
admet-839	40	12	and	and	CCONJ
admet-839	40	13	dissolution	dissolution	NOUN
admet-839	40	14	of	of	ADP
admet-839	40	15	indomethacin	indomethacin	ADJ
admet-839	40	16	tablets	tablet	NOUN
admet-839	40	17	(	(	PUNCT
admet-839	40	18	300	300	NUM
admet-839	40	19	mg	mg	NOUN
admet-839	40	20	)	)	PUNCT
admet-839	40	21	stored	store	VERB
admet-839	40	22	at	at	ADP
admet-839	40	23	30	30	NUM
admet-839	40	24	°	°	NUM
admet-839	40	25	c/23	c/23	ADJ
admet-839	40	26	%	%	NOUN
admet-839	40	27	rh	rh	NOUN
admet-839	40	28	and	and	CCONJ
admet-839	40	29	30	30	NUM
admet-839	40	30	°	°	NUM
admet-839	40	31	c/75	c/75	PROPN
admet-839	40	32	%	%	INTJ
admet-839	40	33	rh	rh	PROPN
admet-839	40	34	for	for	ADP
admet-839	40	35	1	1	NUM
admet-839	40	36	,	,	PUNCT
admet-839	40	37	2	2	NUM
admet-839	40	38	,	,	PUNCT
admet-839	40	39	7	7	NUM
admet-839	40	40	and	and	CCONJ
admet-839	40	41	22	22	NUM
admet-839	40	42	days	day	NOUN
admet-839	40	43	[	[	X
admet-839	40	44	14	14	NUM
admet-839	40	45	]	]	PUNCT
admet-839	40	46	.	.	PUNCT
admet-839	41	1	a	a	DET
admet-839	41	2	trend	trend	NOUN
admet-839	41	3	towards	towards	ADP
admet-839	41	4	decreased	decrease	VERB
admet-839	41	5	dissolution	dissolution	ADJ
admet-839	41	6	rate	rate	NOUN
admet-839	41	7	with	with	ADP
admet-839	41	8	increased	increase	VERB
admet-839	41	9	storage	storage	NOUN
admet-839	41	10	time	time	NOUN
admet-839	41	11	was	be	AUX
admet-839	41	12	observed	observe	VERB
admet-839	41	13	.	.	PUNCT
admet-839	42	1	furthermore	furthermore	ADV
admet-839	42	2	,	,	PUNCT
admet-839	42	3	novakovic	novakovic	PROPN
admet-839	42	4	et	et	PROPN
admet-839	42	5	al	al	PROPN
admet-839	42	6	.	.	PROPN
admet-839	42	7	reported	report	VERB
admet-839	42	8	a	a	DET
admet-839	42	9	delay	delay	NOUN
admet-839	42	10	in	in	ADP
admet-839	42	11	crystallization	crystallization	NOUN
admet-839	42	12	onset	onset	VERB
admet-839	42	13	during	during	ADP
admet-839	42	14	storage	storage	NOUN
admet-839	42	15	and	and	CCONJ
admet-839	42	16	multiple	multiple	ADJ
admet-839	42	17	factors	factor	NOUN
admet-839	42	18	affecting	affect	VERB
admet-839	42	19	dissolution	dissolution	NOUN
admet-839	42	20	of	of	ADP
admet-839	42	21	amorphous	amorphous	ADJ
admet-839	42	22	indomethacin	indomethacin	NOUN
admet-839	42	23	tablets	tablet	NOUN
admet-839	42	24	(	(	PUNCT
admet-839	42	25	500	500	NUM
admet-839	42	26	mg	mg	NOUN
admet-839	42	27	)	)	PUNCT
admet-839	42	28	as	as	ADP
admet-839	42	29	a	a	DET
admet-839	42	30	result	result	NOUN
admet-839	42	31	of	of	ADP
admet-839	42	32	the	the	DET
admet-839	42	33	polymer	polymer	NOUN
admet-839	42	34	coating	coating	NOUN
admet-839	42	35	[	[	X
admet-839	42	36	15	15	NUM
admet-839	42	37	]	]	PUNCT
admet-839	42	38	.	.	PUNCT
admet-839	43	1	by	by	ADP
admet-839	43	2	now	now	ADV
admet-839	43	3	,	,	PUNCT
admet-839	43	4	one	one	PRON
admet-839	43	5	should	should	AUX
admet-839	43	6	note	note	VERB
admet-839	43	7	the	the	DET
admet-839	43	8	amount	amount	NOUN
admet-839	43	9	of	of	ADP
admet-839	43	10	research	research	NOUN
admet-839	43	11	conducted	conduct	VERB
admet-839	43	12	with	with	ADP
admet-839	43	13	amorphous	amorphous	ADJ
admet-839	43	14	indomethacin	indomethacin	NOUN
admet-839	43	15	is	be	AUX
admet-839	43	16	quite	quite	ADV
admet-839	43	17	considerable	considerable	ADJ
admet-839	43	18	.	.	PUNCT
admet-839	44	1	however	however	ADV
admet-839	44	2	,	,	PUNCT
admet-839	44	3	the	the	DET
admet-839	44	4	studies	study	NOUN
admet-839	44	5	that	that	PRON
admet-839	44	6	have	have	AUX
admet-839	44	7	investigated	investigate	VERB
admet-839	44	8	the	the	DET
admet-839	44	9	dissolution	dissolution	NOUN
admet-839	44	10	/	/	SYM
admet-839	44	11	solubility	solubility	NOUN
admet-839	44	12	enhancement	enhancement	NOUN
admet-839	44	13	of	of	ADP
admet-839	44	14	amorphous	amorphous	ADJ
admet-839	44	15	indomethacin	indomethacin	NOUN
admet-839	44	16	–	–	PUNCT
admet-839	44	17	or	or	CCONJ
admet-839	44	18	any	any	DET
admet-839	44	19	other	other	ADJ
admet-839	44	20	amorphous	amorphous	ADJ
admet-839	44	21	drug	drug	NOUN
admet-839	44	22	–	–	PUNCT
admet-839	44	23	throughout	throughout	ADP
admet-839	44	24	the	the	DET
admet-839	44	25	storage	storage	NOUN
admet-839	44	26	time	time	NOUN
admet-839	44	27	are	be	AUX
admet-839	44	28	scarce	scarce	ADJ
admet-839	44	29	.	.	PUNCT
admet-839	45	1	in	in	ADP
admet-839	45	2	our	our	PRON
admet-839	45	3	opinion	opinion	NOUN
admet-839	45	4	,	,	PUNCT
admet-839	45	5	this	this	PRON
admet-839	45	6	is	be	AUX
admet-839	45	7	due	due	ADJ
admet-839	45	8	to	to	ADP
admet-839	45	9	the	the	DET
admet-839	45	10	following	following	ADJ
admet-839	45	11	factors	factor	NOUN
admet-839	45	12	:	:	PUNCT
admet-839	45	13	substantial	substantial	ADJ
admet-839	45	14	amount	amount	NOUN
admet-839	45	15	of	of	ADP
admet-839	45	16	drug	drug	NOUN
admet-839	45	17	compound	compound	NOUN
admet-839	45	18	needed	need	VERB
admet-839	45	19	and	and	CCONJ
admet-839	45	20	challenges	challenge	NOUN
admet-839	45	21	for	for	ADP
admet-839	45	22	analytical	analytical	ADJ
admet-839	45	23	methods	method	NOUN
admet-839	45	24	to	to	PART
admet-839	45	25	detect	detect	VERB
admet-839	45	26	the	the	DET
admet-839	45	27	changes	change	NOUN
admet-839	45	28	in	in	ADP
admet-839	45	29	dissolution	dissolution	NOUN
admet-839	45	30	/	/	SYM
admet-839	45	31	solubility	solubility	NOUN
admet-839	45	32	of	of	ADP
admet-839	45	33	the	the	DET
admet-839	45	34	originally	originally	ADV
admet-839	45	35	amorphous	amorphous	ADJ
admet-839	45	36	sample	sample	NOUN
admet-839	46	1	[	[	X
admet-839	46	2	16	16	NUM
admet-839	46	3	]	]	PUNCT
admet-839	46	4	.	.	PUNCT
admet-839	47	1	nevertheless	nevertheless	ADV
admet-839	47	2	,	,	PUNCT
admet-839	47	3	these	these	DET
admet-839	47	4	studies	study	NOUN
admet-839	47	5	are	be	AUX
admet-839	47	6	highly	highly	ADV
admet-839	47	7	important	important	ADJ
admet-839	47	8	as	as	SCONJ
admet-839	47	9	surfaces	surface	NOUN
admet-839	47	10	dictate	dictate	VERB
admet-839	47	11	the	the	DET
admet-839	47	12	dissolution	dissolution	ADJ
admet-839	47	13	behaviour	behaviour	NOUN
admet-839	47	14	of	of	ADP
admet-839	47	15	pharmaceutical	pharmaceutical	ADJ
admet-839	47	16	compounds	compound	NOUN
admet-839	47	17	and	and	CCONJ
admet-839	47	18	by	by	ADP
admet-839	47	19	understanding	understand	VERB
admet-839	47	20	the	the	DET
admet-839	47	21	processes	process	NOUN
admet-839	47	22	occurring	occur	VERB
admet-839	47	23	on	on	ADP
admet-839	47	24	the	the	DET
admet-839	47	25	surfaces	surface	NOUN
admet-839	47	26	we	we	PRON
admet-839	47	27	can	can	AUX
admet-839	47	28	better	well	ADV
admet-839	47	29	predict	predict	VERB
admet-839	47	30	their	their	PRON
admet-839	47	31	in	in	ADP
admet-839	47	32	vivo	vivo	ADJ
admet-839	47	33	performance	performance	NOUN
admet-839	47	34	.	.	PUNCT
admet-839	48	1	with	with	ADP
admet-839	48	2	the	the	DET
admet-839	48	3	emergence	emergence	NOUN
admet-839	48	4	of	of	ADP
admet-839	48	5	the	the	DET
admet-839	48	6	image	image	NOUN
admet-839	48	7	-	-	PUNCT
admet-839	48	8	based	base	VERB
admet-839	48	9	single	single	ADJ
admet-839	48	10	-	-	PUNCT
admet-839	48	11	particle	particle	NOUN
admet-839	48	12	analysis	analysis	NOUN
admet-839	48	13	(	(	PUNCT
admet-839	48	14	spa	spa	NOUN
admet-839	48	15	)	)	PUNCT
admet-839	48	16	for	for	ADP
admet-839	48	17	determining	determine	VERB
admet-839	48	18	the	the	DET
admet-839	48	19	solubility	solubility	NOUN
admet-839	48	20	(	(	PUNCT
admet-839	48	21	figure	figure	NOUN
admet-839	48	22	1a	1a	NOUN
admet-839	48	23	)	)	PUNCT
admet-839	48	24	,	,	PUNCT
admet-839	48	25	these	these	DET
admet-839	48	26	two	two	NUM
admet-839	48	27	limiting	limit	VERB
admet-839	48	28	factors	factor	NOUN
admet-839	48	29	above	above	ADV
admet-839	48	30	can	can	AUX
admet-839	48	31	be	be	AUX
admet-839	48	32	easily	easily	ADV
admet-839	48	33	tackled	tackle	VERB
admet-839	48	34	[	[	X
admet-839	48	35	17	17	NUM
admet-839	48	36	]	]	PUNCT
admet-839	48	37	.	.	PUNCT
admet-839	49	1	the	the	DET
admet-839	49	2	spa	spa	NOUN
admet-839	49	3	methodology	methodology	NOUN
admet-839	49	4	requires	require	VERB
admet-839	49	5	minuscule	minuscule	ADJ
admet-839	49	6	sample	sample	NOUN
admet-839	49	7	amounts	amount	NOUN
admet-839	49	8	(	(	PUNCT
admet-839	49	9	<	<	X
admet-839	49	10	100	100	NUM
admet-839	49	11	µg	µg	NOUN
admet-839	49	12	)	)	PUNCT
admet-839	49	13	,	,	PUNCT
admet-839	49	14	short	short	ADJ
admet-839	49	15	equilibration	equilibration	NOUN
admet-839	49	16	time	time	NOUN
admet-839	49	17	and	and	CCONJ
admet-839	49	18	it	it	PRON
admet-839	49	19	has	have	AUX
admet-839	49	20	already	already	ADV
admet-839	49	21	proven	prove	VERB
admet-839	49	22	successful	successful	ADJ
admet-839	49	23	in	in	ADP
admet-839	49	24	admet	admet	PROPN
admet-839	49	25	&	&	CCONJ
admet-839	49	26	dmpk	dmpk	PROPN
admet-839	49	27	8(4	8(4	NOUN
admet-839	49	28	)	)	PUNCT
admet-839	49	29	(	(	PUNCT
admet-839	49	30	2020	2020	NUM
admet-839	49	31	)	)	PUNCT
admet-839	49	32	401	401	NUM
admet-839	49	33	-	-	SYM
admet-839	49	34	409	409	NUM
admet-839	49	35	amorphous	amorphous	ADJ
admet-839	49	36	solubility	solubility	NOUN
admet-839	49	37	over	over	ADP
admet-839	49	38	time	time	NOUN
admet-839	49	39	doi	doi	PROPN
admet-839	49	40	:	:	PUNCT
admet-839	49	41	https://dx.doi.org/10.5599/admet.839	https://dx.doi.org/10.5599/admet.839	NOUN
admet-839	49	42	403	403	NUM
admet-839	49	43	directly	directly	ADV
admet-839	49	44	measuring	measure	VERB
admet-839	49	45	the	the	DET
admet-839	49	46	amorphous	amorphous	ADJ
admet-839	49	47	solubility	solubility	NOUN
admet-839	49	48	,	,	PUNCT
admet-839	49	49	also	also	ADV
admet-839	49	50	referred	refer	VERB
admet-839	49	51	to	to	ADP
admet-839	49	52	as	as	ADP
admet-839	49	53	apparent	apparent	ADJ
admet-839	49	54	solubility	solubility	NOUN
admet-839	49	55	,	,	PUNCT
admet-839	49	56	of	of	ADP
admet-839	49	57	several	several	ADJ
admet-839	49	58	compounds	compound	NOUN
admet-839	49	59	[	[	X
admet-839	49	60	18	18	NUM
admet-839	49	61	]	]	PUNCT
admet-839	49	62	.	.	PUNCT
admet-839	50	1	in	in	ADP
admet-839	50	2	this	this	DET
admet-839	50	3	study	study	NOUN
admet-839	50	4	,	,	PUNCT
admet-839	50	5	we	we	PRON
admet-839	50	6	continuously	continuously	ADV
admet-839	50	7	monitor	monitor	VERB
admet-839	50	8	the	the	DET
admet-839	50	9	xrpd	xrpd	PROPN
admet-839	50	10	signal	signal	NOUN
admet-839	50	11	and	and	CCONJ
admet-839	50	12	the	the	DET
admet-839	50	13	solubility	solubility	NOUN
admet-839	50	14	,	,	PUNCT
admet-839	50	15	employing	employ	VERB
admet-839	50	16	spa	spa	NOUN
admet-839	50	17	,	,	PUNCT
admet-839	50	18	of	of	ADP
admet-839	50	19	amorphous	amorphous	ADJ
admet-839	50	20	indomethacin	indomethacin	NOUN
admet-839	50	21	stored	store	VERB
admet-839	50	22	at	at	ADP
admet-839	50	23	two	two	NUM
admet-839	50	24	different	different	ADJ
admet-839	50	25	ambient	ambient	ADJ
admet-839	50	26	conditions	condition	NOUN
admet-839	50	27	for	for	ADP
admet-839	50	28	80	80	NUM
admet-839	50	29	days	day	NOUN
admet-839	50	30	.	.	PUNCT
admet-839	51	1	experimental	experimental	ADJ
admet-839	51	2	materials	material	NOUN
admet-839	51	3	indomethacin	indomethacin	NOUN
admet-839	51	4	(	(	PUNCT
admet-839	51	5	γ	γ	NOUN
admet-839	51	6	form	form	NOUN
admet-839	51	7	)	)	PUNCT
admet-839	51	8	was	be	AUX
admet-839	51	9	received	receive	VERB
admet-839	51	10	from	from	ADP
admet-839	51	11	orion	orion	PROPN
admet-839	51	12	pharma	pharma	PROPN
admet-839	51	13	,	,	PUNCT
admet-839	51	14	espoo	espoo	PROPN
admet-839	51	15	,	,	PUNCT
admet-839	51	16	finland	finland	PROPN
admet-839	51	17	.	.	PUNCT
admet-839	52	1	the	the	DET
admet-839	52	2	α	α	PROPN
admet-839	52	3	form	form	NOUN
admet-839	52	4	was	be	AUX
admet-839	52	5	prepared	prepare	VERB
admet-839	52	6	by	by	ADP
admet-839	52	7	dissolving	dissolve	VERB
admet-839	52	8	3	3	NUM
admet-839	52	9	g	g	NOUN
admet-839	52	10	of	of	ADP
admet-839	52	11	indomethacin	indomethacin	NOUN
admet-839	52	12	in	in	ADP
admet-839	52	13	20	20	NUM
admet-839	52	14	ml	ml	NOUN
admet-839	52	15	of	of	ADP
admet-839	52	16	etoh	etoh	NOUN
admet-839	52	17	and	and	CCONJ
admet-839	52	18	heated	heat	VERB
admet-839	52	19	up	up	ADP
admet-839	52	20	to	to	ADP
admet-839	52	21	70	70	NUM
admet-839	52	22	°	°	NOUN
admet-839	52	23	c	c	NOUN
admet-839	52	24	.	.	PUNCT
admet-839	53	1	upon	upon	SCONJ
admet-839	53	2	complete	complete	ADJ
admet-839	53	3	dissolution	dissolution	NOUN
admet-839	53	4	,	,	PUNCT
admet-839	53	5	the	the	DET
admet-839	53	6	system	system	NOUN
admet-839	53	7	was	be	AUX
admet-839	53	8	kept	keep	VERB
admet-839	53	9	at	at	ADP
admet-839	53	10	the	the	DET
admet-839	53	11	set	set	ADJ
admet-839	53	12	temperature	temperature	NOUN
admet-839	53	13	for	for	ADP
admet-839	53	14	an	an	DET
admet-839	53	15	additional	additional	ADJ
admet-839	53	16	5	5	NUM
admet-839	53	17	min	min	NOUN
admet-839	53	18	and	and	CCONJ
admet-839	53	19	then	then	ADV
admet-839	53	20	rapidly	rapidly	ADV
admet-839	53	21	cooled	cool	VERB
admet-839	53	22	down	down	ADP
admet-839	53	23	in	in	ADP
admet-839	53	24	an	an	DET
admet-839	53	25	ice	ice	NOUN
admet-839	53	26	bath	bath	NOUN
admet-839	53	27	.	.	PUNCT
admet-839	54	1	the	the	DET
admet-839	54	2	formed	form	VERB
admet-839	54	3	slurry	slurry	NOUN
admet-839	54	4	was	be	AUX
admet-839	54	5	filtered	filter	VERB
admet-839	54	6	and	and	CCONJ
admet-839	54	7	dried	dry	VERB
admet-839	54	8	in	in	ADP
admet-839	54	9	a	a	DET
admet-839	54	10	vacuum	vacuum	NOUN
admet-839	54	11	oven	oven	NOUN
admet-839	54	12	at	at	ADP
admet-839	54	13	70	70	NUM
admet-839	54	14	°	°	ADP
admet-839	54	15	c	c	NOUN
admet-839	54	16	for	for	ADP
admet-839	54	17	1	1	NUM
admet-839	54	18	h.	h.	PROPN
admet-839	54	19	amorphous	amorphous	ADJ
admet-839	54	20	indomethacin	indomethacin	PROPN
admet-839	54	21	was	be	AUX
admet-839	54	22	prepared	prepare	VERB
admet-839	54	23	by	by	ADP
admet-839	54	24	melting	melt	VERB
admet-839	54	25	the	the	DET
admet-839	54	26	γ	γ	PROPN
admet-839	54	27	form	form	NOUN
admet-839	54	28	on	on	ADP
admet-839	54	29	a	a	DET
admet-839	54	30	hot	hot	ADJ
admet-839	54	31	plate	plate	NOUN
admet-839	54	32	at	at	ADP
admet-839	54	33	165	165	NUM
admet-839	54	34	°	°	NOUN
admet-839	54	35	c	c	NOUN
admet-839	54	36	.	.	PUNCT
admet-839	55	1	after	after	ADP
admet-839	55	2	visual	visual	ADJ
admet-839	55	3	confirmation	confirmation	NOUN
admet-839	55	4	of	of	ADP
admet-839	55	5	complete	complete	ADJ
admet-839	55	6	melting	melting	NOUN
admet-839	55	7	,	,	PUNCT
admet-839	55	8	the	the	DET
admet-839	55	9	melt	melt	NOUN
admet-839	55	10	was	be	AUX
admet-839	55	11	kept	keep	VERB
admet-839	55	12	on	on	ADP
admet-839	55	13	a	a	DET
admet-839	55	14	hot	hot	ADJ
admet-839	55	15	plate	plate	NOUN
admet-839	55	16	for	for	ADP
admet-839	55	17	additional	additional	ADJ
admet-839	55	18	30	30	NUM
admet-839	55	19	seconds	second	NOUN
admet-839	55	20	.	.	PUNCT
admet-839	56	1	after	after	ADP
admet-839	56	2	30	30	NUM
admet-839	56	3	seconds	second	NOUN
admet-839	56	4	,	,	PUNCT
admet-839	56	5	the	the	DET
admet-839	56	6	melt	melt	NOUN
admet-839	56	7	was	be	AUX
admet-839	56	8	immediately	immediately	ADV
admet-839	56	9	cooled	cool	VERB
admet-839	56	10	down	down	ADP
admet-839	56	11	on	on	ADP
admet-839	56	12	an	an	DET
admet-839	56	13	aluminium	aluminium	NOUN
admet-839	56	14	heat	heat	NOUN
admet-839	56	15	sink	sink	NOUN
admet-839	56	16	.	.	PUNCT
admet-839	57	1	it	it	PRON
admet-839	57	2	has	have	AUX
admet-839	57	3	been	be	AUX
admet-839	57	4	shown	show	VERB
admet-839	57	5	previously	previously	ADV
admet-839	57	6	that	that	SCONJ
admet-839	57	7	this	this	DET
admet-839	57	8	preparative	preparative	ADJ
admet-839	57	9	technique	technique	NOUN
admet-839	57	10	does	do	AUX
admet-839	57	11	not	not	PART
admet-839	57	12	cause	cause	VERB
admet-839	57	13	significant	significant	ADJ
admet-839	57	14	sample	sample	NOUN
admet-839	57	15	degradation	degradation	NOUN
admet-839	58	1	[	[	X
admet-839	58	2	19–21	19–21	NUM
admet-839	58	3	]	]	PUNCT
admet-839	58	4	.	.	PUNCT
admet-839	59	1	the	the	DET
admet-839	59	2	quench	quench	NOUN
admet-839	59	3	cooled	cool	VERB
admet-839	59	4	melt	melt	NOUN
admet-839	59	5	was	be	AUX
admet-839	59	6	then	then	ADV
admet-839	59	7	stored	store	VERB
admet-839	59	8	over	over	ADP
admet-839	59	9	phosphorus	phosphorus	NOUN
admet-839	59	10	pentoxide	pentoxide	NOUN
admet-839	59	11	at	at	ADP
admet-839	59	12	room	room	NOUN
admet-839	59	13	temperature	temperature	NOUN
admet-839	59	14	for	for	ADP
admet-839	59	15	one	one	NUM
admet-839	59	16	hour	hour	NOUN
admet-839	59	17	.	.	PUNCT
admet-839	60	1	after	after	ADP
admet-839	60	2	one	one	NUM
admet-839	60	3	hour	hour	NOUN
admet-839	60	4	,	,	PUNCT
admet-839	60	5	the	the	DET
admet-839	60	6	amorphous	amorphous	ADJ
admet-839	60	7	indomethacin	indomethacin	NOUN
admet-839	60	8	was	be	AUX
admet-839	60	9	gently	gently	ADV
admet-839	60	10	ground	grind	VERB
admet-839	60	11	with	with	ADP
admet-839	60	12	a	a	DET
admet-839	60	13	mortar	mortar	NOUN
admet-839	60	14	and	and	CCONJ
admet-839	60	15	pestle	pestle	NOUN
admet-839	60	16	.	.	PUNCT
admet-839	61	1	a	a	DET
admet-839	61	2	small	small	ADJ
admet-839	61	3	amount	amount	NOUN
admet-839	61	4	of	of	ADP
admet-839	61	5	the	the	DET
admet-839	61	6	sample	sample	NOUN
admet-839	61	7	was	be	AUX
admet-839	61	8	taken	take	VERB
admet-839	61	9	for	for	ADP
admet-839	61	10	the	the	DET
admet-839	61	11	dsc	dsc	NOUN
admet-839	61	12	analysis	analysis	NOUN
admet-839	61	13	and	and	CCONJ
admet-839	61	14	the	the	DET
admet-839	61	15	remaining	remain	VERB
admet-839	61	16	amount	amount	NOUN
admet-839	61	17	was	be	AUX
admet-839	61	18	halved	halve	VERB
admet-839	61	19	and	and	CCONJ
admet-839	61	20	placed	place	VERB
admet-839	61	21	into	into	ADP
admet-839	61	22	two	two	NUM
admet-839	61	23	xrpd	xrpd	ADJ
admet-839	61	24	holders	holder	NOUN
admet-839	61	25	with	with	ADP
admet-839	61	26	a	a	DET
admet-839	61	27	low	low	ADJ
admet-839	61	28	-	-	PUNCT
admet-839	61	29	scatter	scatter	NOUN
admet-839	61	30	background	background	NOUN
admet-839	61	31	(	(	PUNCT
admet-839	61	32	figure	figure	NOUN
admet-839	61	33	1b	1b	NUM
admet-839	61	34	)	)	PUNCT
admet-839	61	35	.	.	PUNCT
admet-839	62	1	figure	figure	NOUN
admet-839	62	2	1	1	NUM
admet-839	62	3	.	.	PUNCT
admet-839	63	1	(	(	PUNCT
admet-839	63	2	a	a	X
admet-839	63	3	)	)	PUNCT
admet-839	63	4	schematic	schematic	ADJ
admet-839	63	5	of	of	ADP
admet-839	63	6	the	the	DET
admet-839	63	7	single	single	ADJ
admet-839	63	8	-	-	PUNCT
admet-839	63	9	particle	particle	NOUN
admet-839	63	10	analysis	analysis	NOUN
admet-839	63	11	(	(	PUNCT
admet-839	63	12	spa	spa	NOUN
admet-839	63	13	)	)	PUNCT
admet-839	63	14	setup	setup	NOUN
admet-839	63	15	.	.	PUNCT
admet-839	64	1	(	(	PUNCT
admet-839	64	2	b	b	X
admet-839	64	3	)	)	PUNCT
admet-839	64	4	schematic	schematic	ADJ
admet-839	64	5	of	of	ADP
admet-839	64	6	the	the	DET
admet-839	64	7	low	low	ADJ
admet-839	64	8	-	-	PUNCT
admet-839	64	9	scatterbackground	scatterbackground	NOUN
admet-839	64	10	holder	holder	NOUN
admet-839	64	11	and	and	CCONJ
admet-839	64	12	sampling	sample	VERB
admet-839	64	13	protocol	protocol	NOUN
admet-839	64	14	used	use	VERB
admet-839	64	15	in	in	ADP
admet-839	64	16	the	the	DET
admet-839	64	17	study	study	NOUN
admet-839	64	18	.	.	PUNCT
admet-839	65	1	the	the	DET
admet-839	65	2	middle	middle	ADJ
admet-839	65	3	area	area	NOUN
admet-839	65	4	(	(	PUNCT
admet-839	65	5	red	red	PROPN
admet-839	65	6	)	)	PUNCT
admet-839	65	7	was	be	AUX
admet-839	65	8	scanned	scan	VERB
admet-839	65	9	,	,	PUNCT
admet-839	65	10	on	on	ADP
admet-839	65	11	the	the	DET
admet-839	65	12	measuring	measure	VERB
admet-839	65	13	days	day	NOUN
admet-839	65	14	,	,	PUNCT
admet-839	65	15	with	with	ADP
admet-839	65	16	the	the	DET
admet-839	65	17	xrpd	xrpd	PROPN
admet-839	65	18	and	and	CCONJ
admet-839	65	19	was	be	AUX
admet-839	65	20	not	not	PART
admet-839	65	21	altered	alter	VERB
admet-839	65	22	throughout	throughout	ADP
admet-839	65	23	the	the	DET
admet-839	65	24	course	course	NOUN
admet-839	65	25	of	of	ADP
admet-839	65	26	the	the	DET
admet-839	65	27	study	study	NOUN
admet-839	65	28	.	.	PUNCT
admet-839	66	1	the	the	DET
admet-839	66	2	spa	spa	NOUN
admet-839	66	3	sampling	sample	VERB
admet-839	66	4	area	area	NOUN
admet-839	66	5	was	be	AUX
admet-839	66	6	between	between	ADP
admet-839	66	7	the	the	DET
admet-839	66	8	xrpd	xrpd	PROPN
admet-839	66	9	scan	scan	PROPN
admet-839	66	10	area	area	NOUN
admet-839	66	11	and	and	CCONJ
admet-839	66	12	the	the	DET
admet-839	66	13	flush	flush	ADJ
admet-839	66	14	aluminium	aluminium	NOUN
admet-839	66	15	surface	surface	NOUN
admet-839	66	16	of	of	ADP
admet-839	66	17	the	the	DET
admet-839	66	18	holder	holder	NOUN
admet-839	66	19	(	(	PUNCT
admet-839	66	20	grey	grey	PROPN
admet-839	66	21	)	)	PUNCT
admet-839	66	22	.	.	PUNCT
admet-839	67	1	on	on	ADP
admet-839	67	2	the	the	DET
admet-839	67	3	measuring	measure	VERB
admet-839	67	4	day	day	NOUN
admet-839	67	5	,	,	PUNCT
admet-839	67	6	three	three	NUM
admet-839	67	7	samples	sample	NOUN
admet-839	67	8	from	from	ADP
admet-839	67	9	this	this	DET
admet-839	67	10	area	area	NOUN
admet-839	67	11	were	be	AUX
admet-839	67	12	taken	take	VERB
admet-839	67	13	with	with	ADP
admet-839	67	14	a	a	DET
admet-839	67	15	spatula	spatula	NOUN
admet-839	67	16	from	from	ADP
admet-839	67	17	opposite	opposite	ADJ
admet-839	67	18	sides	side	NOUN
admet-839	67	19	of	of	ADP
admet-839	67	20	the	the	DET
admet-839	67	21	holder	holder	NOUN
admet-839	67	22	starting	start	VERB
admet-839	67	23	with	with	ADP
admet-839	67	24	day	day	NOUN
admet-839	67	25	zero	zero	NUM
admet-839	67	26	at	at	ADP
admet-839	67	27	the	the	DET
admet-839	67	28	three	three	NUM
admet-839	67	29	dashed	dash	VERB
admet-839	67	30	lines	line	NOUN
admet-839	67	31	and	and	CCONJ
admet-839	67	32	then	then	ADV
admet-839	67	33	moving	move	VERB
admet-839	67	34	clockwise	clockwise	NOUN
admet-839	67	35	with	with	ADP
admet-839	67	36	each	each	DET
admet-839	67	37	consecutive	consecutive	ADJ
admet-839	67	38	measuring	measure	VERB
admet-839	67	39	day	day	NOUN
admet-839	67	40	.	.	PUNCT
admet-839	68	1	in	in	ADP
admet-839	68	2	that	that	DET
admet-839	68	3	way	way	NOUN
admet-839	68	4	,	,	PUNCT
admet-839	68	5	the	the	DET
admet-839	68	6	sampling	sample	VERB
admet-839	68	7	area	area	NOUN
admet-839	68	8	distribution	distribution	NOUN
admet-839	68	9	was	be	AUX
admet-839	68	10	maximized	maximize	VERB
admet-839	68	11	and	and	CCONJ
admet-839	68	12	no	no	DET
admet-839	68	13	spot	spot	NOUN
admet-839	68	14	was	be	AUX
admet-839	68	15	sampled	sample	VERB
admet-839	68	16	more	more	ADV
admet-839	68	17	than	than	ADP
admet-839	68	18	once	once	ADV
admet-839	68	19	.	.	PUNCT
admet-839	69	1	storage	storage	NOUN
admet-839	69	2	conditions	condition	NOUN
admet-839	69	3	one	one	NUM
admet-839	69	4	of	of	ADP
admet-839	69	5	the	the	DET
admet-839	69	6	two	two	NUM
admet-839	69	7	sample	sample	NOUN
admet-839	69	8	holders	holder	NOUN
admet-839	69	9	with	with	ADP
admet-839	69	10	the	the	DET
admet-839	69	11	amorphous	amorphous	ADJ
admet-839	69	12	indomethacin	indomethacin	NOUN
admet-839	69	13	was	be	AUX
admet-839	69	14	stored	store	VERB
admet-839	69	15	at	at	ADP
admet-839	69	16	23	23	NUM
admet-839	69	17	%	%	NOUN
admet-839	69	18	rh	rh	NOUN
admet-839	69	19	and	and	CCONJ
admet-839	69	20	the	the	DET
admet-839	69	21	other	other	ADJ
admet-839	69	22	at	at	ADP
admet-839	69	23	75	75	NUM
admet-839	69	24	%	%	NOUN
admet-839	69	25	rh	rh	PROPN
admet-839	69	26	.	.	PUNCT
admet-839	70	1	both	both	DET
admet-839	70	2	samples	sample	NOUN
admet-839	70	3	were	be	AUX
admet-839	70	4	kept	keep	VERB
admet-839	70	5	at	at	ADP
admet-839	70	6	22±0.5	22±0.5	NUM
admet-839	70	7	°	°	NOUN
admet-839	70	8	c	c	NOUN
admet-839	70	9	.	.	PUNCT
admet-839	71	1	http://dx.doi.org/10.5599/admet.839	http://dx.doi.org/10.5599/admet.839	PROPN
admet-839	71	2	jernej	jernej	PROPN
admet-839	71	3	štukelj	štukelj	PROPN
admet-839	71	4	et	et	PROPN
admet-839	71	5	al	al	PROPN
admet-839	71	6	.	.	PROPN
admet-839	71	7	admet	admet	PROPN
admet-839	71	8	&	&	CCONJ
admet-839	71	9	dmpk	dmpk	PROPN
admet-839	71	10	8(4	8(4	NOUN
admet-839	71	11	)	)	PUNCT
admet-839	71	12	(	(	PUNCT
admet-839	71	13	2020	2020	NUM
admet-839	71	14	)	)	PUNCT
admet-839	71	15	401	401	NUM
admet-839	71	16	-	-	SYM
admet-839	71	17	409	409	NUM
admet-839	71	18	404	404	NUM
admet-839	71	19	differential	differential	NOUN
admet-839	71	20	scanning	scan	VERB
admet-839	71	21	calorimetry	calorimetry	NOUN
admet-839	71	22	(	(	PUNCT
admet-839	71	23	dsc	dsc	NOUN
admet-839	71	24	)	)	PUNCT
admet-839	71	25	dsc	dsc	NOUN
admet-839	71	26	measurements	measurement	NOUN
admet-839	71	27	were	be	AUX
admet-839	71	28	conducted	conduct	VERB
admet-839	71	29	to	to	PART
admet-839	71	30	characterize	characterize	VERB
admet-839	71	31	the	the	DET
admet-839	71	32	solid	solid	ADJ
admet-839	71	33	-	-	PUNCT
admet-839	71	34	state	state	NOUN
admet-839	71	35	of	of	ADP
admet-839	71	36	crystalline	crystalline	NOUN
admet-839	71	37	and	and	CCONJ
admet-839	71	38	amorphous	amorphous	ADJ
admet-839	71	39	samples	sample	NOUN
admet-839	71	40	.	.	PUNCT
admet-839	72	1	samples	sample	NOUN
admet-839	72	2	(	(	PUNCT
admet-839	72	3	2	2	NUM
admet-839	72	4	to	to	PART
admet-839	72	5	5	5	NUM
admet-839	72	6	mg	mg	NOUN
admet-839	72	7	)	)	PUNCT
admet-839	72	8	were	be	AUX
admet-839	72	9	packed	pack	VERB
admet-839	72	10	into	into	ADP
admet-839	72	11	standard	standard	ADJ
admet-839	72	12	aluminium	aluminium	NOUN
admet-839	72	13	crucibles	crucible	NOUN
admet-839	72	14	(	(	PUNCT
admet-839	72	15	40	40	NUM
admet-839	72	16	µl	µl	NOUN
admet-839	72	17	)	)	PUNCT
admet-839	72	18	with	with	ADP
admet-839	72	19	pierced	pierced	ADJ
admet-839	72	20	lids	lid	NOUN
admet-839	72	21	.	.	PUNCT
admet-839	73	1	the	the	DET
admet-839	73	2	samples	sample	NOUN
admet-839	73	3	were	be	AUX
admet-839	73	4	analysed	analyse	VERB
admet-839	73	5	with	with	ADP
admet-839	73	6	a	a	DET
admet-839	73	7	dsc823e	dsc823e	X
admet-839	73	8	instrument	instrument	NOUN
admet-839	73	9	(	(	PUNCT
admet-839	73	10	mettler	mettler	PROPN
admet-839	73	11	-	-	PROPN
admet-839	73	12	toledo	toledo	PROPN
admet-839	73	13	,	,	PUNCT
admet-839	73	14	greifensee	greifensee	ADJ
admet-839	73	15	,	,	PUNCT
admet-839	73	16	switzerland	switzerland	PROPN
admet-839	73	17	)	)	PUNCT
admet-839	73	18	equipped	equip	VERB
admet-839	73	19	with	with	ADP
admet-839	73	20	a	a	DET
admet-839	73	21	cooling	cool	VERB
admet-839	73	22	system	system	NOUN
admet-839	73	23	(	(	PUNCT
admet-839	73	24	julabo	julabo	NOUN
admet-839	73	25	ft	ft	ADP
admet-839	73	26	900	900	NUM
admet-839	73	27	,	,	PUNCT
admet-839	73	28	seelbach	seelbach	PROPN
admet-839	73	29	,	,	PUNCT
admet-839	73	30	germany	germany	PROPN
admet-839	73	31	)	)	PUNCT
admet-839	73	32	.	.	PUNCT
admet-839	74	1	nitrogen	nitrogen	NOUN
admet-839	74	2	(	(	PUNCT
admet-839	74	3	50	50	NUM
admet-839	74	4	ml	ml	NOUN
admet-839	74	5	/	/	SYM
admet-839	74	6	min	min	NOUN
admet-839	74	7	)	)	PUNCT
admet-839	74	8	was	be	AUX
admet-839	74	9	used	use	VERB
admet-839	74	10	as	as	ADP
admet-839	74	11	a	a	DET
admet-839	74	12	purge	purge	NOUN
admet-839	74	13	gas	gas	NOUN
admet-839	74	14	.	.	PUNCT
admet-839	75	1	equilibration	equilibration	NOUN
admet-839	75	2	at	at	ADP
admet-839	75	3	25	25	NUM
admet-839	75	4	°	°	NOUN
admet-839	75	5	c	c	NOUN
admet-839	75	6	for	for	ADP
admet-839	75	7	3	3	NUM
admet-839	75	8	minutes	minute	NOUN
admet-839	75	9	was	be	AUX
admet-839	75	10	followed	follow	VERB
admet-839	75	11	by	by	ADP
admet-839	75	12	linear	linear	NOUN
admet-839	75	13	heating	heating	NOUN
admet-839	75	14	with	with	ADP
admet-839	75	15	a	a	DET
admet-839	75	16	heating	heating	NOUN
admet-839	75	17	rate	rate	NOUN
admet-839	75	18	of	of	ADP
admet-839	75	19	10	10	NUM
admet-839	75	20	°	°	NOUN
admet-839	75	21	c	c	PROPN
admet-839	75	22	/	/	SYM
admet-839	75	23	min	min	NOUN
admet-839	75	24	.	.	PROPN
admet-839	75	25	measurements	measurement	NOUN
admet-839	75	26	were	be	AUX
admet-839	75	27	made	make	VERB
admet-839	75	28	in	in	ADP
admet-839	75	29	triplicate	triplicate	NOUN
admet-839	75	30	.	.	PUNCT
admet-839	76	1	thermal	thermal	ADJ
admet-839	76	2	events	event	NOUN
admet-839	76	3	were	be	AUX
admet-839	76	4	analysed	analyse	VERB
admet-839	76	5	using	use	VERB
admet-839	76	6	the	the	DET
admet-839	76	7	stare	stare	ADJ
admet-839	76	8	software	software	NOUN
admet-839	76	9	(	(	PUNCT
admet-839	76	10	mettlertoledo	mettlertoledo	NOUN
admet-839	76	11	,	,	PUNCT
admet-839	76	12	greifensee	greifensee	ADJ
admet-839	76	13	,	,	PUNCT
admet-839	76	14	switzerland	switzerland	PROPN
admet-839	76	15	)	)	PUNCT
admet-839	76	16	.	.	PUNCT
admet-839	77	1	x	x	X
admet-839	77	2	-	-	PUNCT
admet-839	77	3	ray	ray	NOUN
admet-839	77	4	powder	powder	NOUN
admet-839	77	5	diffraction	diffraction	NOUN
admet-839	77	6	(	(	PUNCT
admet-839	77	7	xrpd	xrpd	ADJ
admet-839	77	8	)	)	PUNCT
admet-839	77	9	xrpd	xrpd	PROPN
admet-839	78	1	diffractograms	diffractogram	NOUN
admet-839	78	2	were	be	AUX
admet-839	78	3	recorded	record	VERB
admet-839	78	4	to	to	PART
admet-839	78	5	characterize	characterize	VERB
admet-839	78	6	the	the	DET
admet-839	78	7	solid	solid	ADJ
admet-839	78	8	-	-	PUNCT
admet-839	78	9	state	state	NOUN
admet-839	78	10	of	of	ADP
admet-839	78	11	the	the	DET
admet-839	78	12	crystalline	crystalline	ADJ
admet-839	78	13	and	and	CCONJ
admet-839	78	14	amorphous	amorphous	ADJ
admet-839	78	15	samples	sample	NOUN
admet-839	78	16	.	.	PUNCT
admet-839	79	1	moreover	moreover	ADV
admet-839	79	2	,	,	PUNCT
admet-839	79	3	xrpd	xrpd	PROPN
admet-839	79	4	was	be	AUX
admet-839	79	5	used	use	VERB
admet-839	79	6	to	to	PART
admet-839	79	7	follow	follow	VERB
admet-839	79	8	the	the	DET
admet-839	79	9	solid	solid	ADJ
admet-839	79	10	-	-	PUNCT
admet-839	79	11	state	state	NOUN
admet-839	79	12	changes	change	NOUN
admet-839	79	13	of	of	ADP
admet-839	79	14	the	the	DET
admet-839	79	15	two	two	NUM
admet-839	79	16	amorphous	amorphous	ADJ
admet-839	79	17	samples	sample	NOUN
admet-839	79	18	over	over	ADP
admet-839	79	19	time	time	NOUN
admet-839	79	20	(	(	PUNCT
admet-839	79	21	figure	figure	NOUN
admet-839	79	22	1b	1b	NUM
admet-839	79	23	)	)	PUNCT
admet-839	79	24	.	.	PUNCT
admet-839	80	1	an	an	DET
admet-839	80	2	aeris	aeris	PROPN
admet-839	80	3	diffractometer	diffractometer	NOUN
admet-839	80	4	(	(	PUNCT
admet-839	80	5	malvern	malvern	PROPN
admet-839	80	6	panalytical	panalytical	PROPN
admet-839	80	7	b.v	b.v	PROPN
admet-839	80	8	.	.	PROPN
admet-839	80	9	,	,	PUNCT
admet-839	80	10	almelo	almelo	NOUN
admet-839	80	11	,	,	PUNCT
admet-839	80	12	netherlands	netherlands	PROPN
admet-839	80	13	)	)	PUNCT
admet-839	80	14	using	use	VERB
admet-839	80	15	cu	cu	PROPN
admet-839	80	16	kα	kα	PROPN
admet-839	80	17	radiation	radiation	NOUN
admet-839	80	18	(	(	PUNCT
admet-839	80	19	λ	λ	X
admet-839	80	20	=	=	NOUN
admet-839	80	21	1	1	NUM
admet-839	80	22	.	.	NUM
admet-839	80	23	1.540598	1.540598	NUM
admet-839	80	24	å	å	NOUN
admet-839	80	25	)	)	PUNCT
admet-839	80	26	and	and	CCONJ
admet-839	80	27	a	a	DET
admet-839	80	28	divergence	divergence	NOUN
admet-839	80	29	slit	slit	NOUN
admet-839	80	30	of	of	ADP
admet-839	80	31	0.76	0.76	NUM
admet-839	80	32	mm	mm	NOUN
admet-839	80	33	was	be	AUX
admet-839	80	34	used	use	VERB
admet-839	80	35	.	.	PUNCT
admet-839	81	1	samples	sample	NOUN
admet-839	81	2	were	be	AUX
admet-839	81	3	placed	place	VERB
admet-839	81	4	on	on	ADP
admet-839	81	5	a	a	DET
admet-839	81	6	lowscatter	lowscatter	ADJ
admet-839	81	7	-	-	PUNCT
admet-839	81	8	background	background	NOUN
admet-839	81	9	holder	holder	NOUN
admet-839	81	10	and	and	CCONJ
admet-839	81	11	measured	measure	VERB
admet-839	81	12	with	with	ADP
admet-839	81	13	a	a	DET
admet-839	81	14	step	step	NOUN
admet-839	81	15	size	size	NOUN
admet-839	81	16	of	of	ADP
admet-839	81	17	0.0108664	0.0108664	NUM
admet-839	81	18	°	°	NOUN
admet-839	81	19	at	at	ADP
admet-839	81	20	40	40	NUM
admet-839	81	21	kv	kv	PROPN
admet-839	81	22	and	and	CCONJ
admet-839	81	23	8.0	8.0	NUM
admet-839	81	24	ma	ma	PROPN
admet-839	81	25	from	from	ADP
admet-839	81	26	5	5	NUM
admet-839	81	27	°	°	NOUN
admet-839	81	28	to	to	ADP
admet-839	81	29	35	35	NUM
admet-839	81	30	°	°	NOUN
admet-839	81	31	(	(	PUNCT
admet-839	81	32	2θ	2θ	NUM
admet-839	81	33	)	)	PUNCT
admet-839	81	34	.	.	PUNCT
admet-839	82	1	the	the	DET
admet-839	82	2	xrpd	xrpd	PROPN
admet-839	82	3	measurements	measurement	NOUN
admet-839	82	4	of	of	ADP
admet-839	82	5	the	the	DET
admet-839	82	6	two	two	NUM
admet-839	82	7	amorphous	amorphous	ADJ
admet-839	82	8	samples	sample	NOUN
admet-839	82	9	were	be	AUX
admet-839	82	10	carried	carry	VERB
admet-839	82	11	out	out	ADP
admet-839	82	12	on	on	ADP
admet-839	82	13	the	the	DET
admet-839	82	14	following	following	ADJ
admet-839	82	15	days	day	NOUN
admet-839	82	16	:	:	PUNCT
admet-839	82	17	0	0	NUM
admet-839	82	18	,	,	PUNCT
admet-839	82	19	2	2	NUM
admet-839	82	20	,	,	PUNCT
admet-839	82	21	4	4	NUM
admet-839	82	22	,	,	PUNCT
admet-839	82	23	7	7	NUM
admet-839	82	24	,	,	PUNCT
admet-839	82	25	10	10	NUM
admet-839	82	26	,	,	PUNCT
admet-839	82	27	14	14	NUM
admet-839	82	28	,	,	PUNCT
admet-839	82	29	17	17	NUM
admet-839	82	30	,	,	PUNCT
admet-839	82	31	21	21	NUM
admet-839	82	32	,	,	PUNCT
admet-839	82	33	25	25	NUM
admet-839	82	34	,	,	PUNCT
admet-839	82	35	29	29	NUM
admet-839	82	36	,	,	PUNCT
admet-839	82	37	32	32	NUM
admet-839	82	38	,	,	PUNCT
admet-839	82	39	38	38	NUM
admet-839	82	40	,	,	PUNCT
admet-839	82	41	44	44	NUM
admet-839	82	42	,	,	PUNCT
admet-839	82	43	53	53	NUM
admet-839	82	44	,	,	PUNCT
admet-839	82	45	60	60	NUM
admet-839	82	46	and	and	CCONJ
admet-839	82	47	80	80	NUM
admet-839	82	48	.	.	PUNCT
admet-839	83	1	the	the	DET
admet-839	83	2	height	height	NOUN
admet-839	83	3	of	of	ADP
admet-839	83	4	the	the	DET
admet-839	83	5	peaks	peak	NOUN
admet-839	83	6	at	at	ADP
admet-839	83	7	11.6	11.6	NUM
admet-839	83	8	°	°	NOUN
admet-839	83	9	,	,	PUNCT
admet-839	83	10	16.7	16.7	NUM
admet-839	83	11	°	°	NOUN
admet-839	83	12	,	,	PUNCT
admet-839	83	13	21.8	21.8	NUM
admet-839	83	14	°	°	NOUN
admet-839	83	15	and	and	CCONJ
admet-839	83	16	26.6	26.6	NUM
admet-839	83	17	°	°	NOUN
admet-839	83	18	of	of	ADP
admet-839	83	19	the	the	DET
admet-839	83	20	2θ	2θ	NUM
admet-839	83	21	angle	angle	NOUN
admet-839	83	22	was	be	AUX
admet-839	83	23	used	use	VERB
admet-839	83	24	to	to	PART
admet-839	83	25	quantify	quantify	VERB
admet-839	83	26	the	the	DET
admet-839	83	27	solid	solid	ADJ
admet-839	83	28	-	-	PUNCT
admet-839	83	29	state	state	NOUN
admet-839	83	30	change	change	NOUN
admet-839	83	31	that	that	PRON
admet-839	83	32	occurred	occur	VERB
admet-839	83	33	.	.	PUNCT
admet-839	84	1	the	the	DET
admet-839	84	2	height	height	NOUN
admet-839	84	3	of	of	ADP
admet-839	84	4	each	each	DET
admet-839	84	5	peak	peak	NOUN
admet-839	84	6	was	be	AUX
admet-839	84	7	divided	divide	VERB
admet-839	84	8	by	by	ADP
admet-839	84	9	the	the	DET
admet-839	84	10	height	height	NOUN
admet-839	84	11	of	of	ADP
admet-839	84	12	the	the	DET
admet-839	84	13	silicon	silicon	NOUN
admet-839	84	14	peak	peak	NOUN
admet-839	84	15	(	(	PUNCT
admet-839	84	16	28.4	28.4	NUM
admet-839	84	17	°	°	NOUN
admet-839	84	18	)	)	PUNCT
admet-839	84	19	measured	measure	VERB
admet-839	84	20	on	on	ADP
admet-839	84	21	the	the	DET
admet-839	84	22	same	same	ADJ
admet-839	84	23	day	day	NOUN
admet-839	84	24	to	to	PART
admet-839	84	25	correct	correct	VERB
admet-839	84	26	the	the	DET
admet-839	84	27	response	response	NOUN
admet-839	84	28	for	for	ADP
admet-839	84	29	the	the	DET
admet-839	84	30	fluctuation	fluctuation	NOUN
admet-839	84	31	of	of	ADP
admet-839	84	32	the	the	DET
admet-839	84	33	x	x	ADJ
admet-839	84	34	-	-	NOUN
admet-839	84	35	ray	ray	NOUN
admet-839	84	36	beam	beam	NOUN
admet-839	84	37	.	.	PUNCT
admet-839	85	1	the	the	DET
admet-839	85	2	silicon	silicon	NOUN
admet-839	85	3	peak	peak	NOUN
admet-839	85	4	was	be	AUX
admet-839	85	5	measured	measure	VERB
admet-839	85	6	from	from	ADP
admet-839	85	7	the	the	DET
admet-839	85	8	silicon	silicon	NOUN
admet-839	85	9	plate	plate	NOUN
admet-839	85	10	provided	provide	VERB
admet-839	85	11	by	by	ADP
admet-839	85	12	malvern	malvern	PROPN
admet-839	85	13	panalytical	panalytical	PROPN
admet-839	85	14	.	.	PUNCT
admet-839	86	1	the	the	DET
admet-839	86	2	four	four	NUM
admet-839	86	3	corrected	correct	VERB
admet-839	86	4	peak	peak	NOUN
admet-839	86	5	height	height	NOUN
admet-839	86	6	values	value	NOUN
admet-839	86	7	were	be	AUX
admet-839	86	8	then	then	ADV
admet-839	86	9	averaged	average	VERB
admet-839	86	10	in	in	ADP
admet-839	86	11	order	order	NOUN
admet-839	86	12	to	to	PART
admet-839	86	13	obtain	obtain	VERB
admet-839	86	14	a	a	DET
admet-839	86	15	single	single	ADJ
admet-839	86	16	quantifying	quantify	VERB
admet-839	86	17	value	value	NOUN
admet-839	86	18	.	.	PUNCT
admet-839	87	1	single	single	ADJ
admet-839	87	2	-	-	PUNCT
admet-839	87	3	particle	particle	NOUN
admet-839	87	4	analysis	analysis	NOUN
admet-839	87	5	(	(	PUNCT
admet-839	87	6	spa	spa	NOUN
admet-839	87	7	)	)	PUNCT
admet-839	87	8	sampling	sampling	NOUN
admet-839	87	9	of	of	ADP
admet-839	87	10	the	the	DET
admet-839	87	11	two	two	NUM
admet-839	87	12	amorphous	amorphous	ADJ
admet-839	87	13	samples	sample	NOUN
admet-839	87	14	stored	store	VERB
admet-839	87	15	at	at	ADP
admet-839	87	16	23	23	NUM
admet-839	87	17	%	%	NOUN
admet-839	87	18	and	and	CCONJ
admet-839	87	19	75	75	NUM
admet-839	87	20	%	%	NOUN
admet-839	87	21	rh	rh	PROPN
admet-839	87	22	was	be	AUX
admet-839	87	23	carried	carry	VERB
admet-839	87	24	out	out	ADP
admet-839	87	25	as	as	SCONJ
admet-839	87	26	presented	present	VERB
admet-839	87	27	in	in	ADP
admet-839	87	28	figure	figure	NOUN
admet-839	87	29	1	1	NUM
admet-839	87	30	.	.	PUNCT
admet-839	88	1	on	on	ADP
admet-839	88	2	each	each	PRON
admet-839	88	3	of	of	ADP
admet-839	88	4	the	the	DET
admet-839	88	5	measuring	measure	VERB
admet-839	88	6	days	day	NOUN
admet-839	88	7	(	(	PUNCT
admet-839	88	8	0	0	NUM
admet-839	88	9	,	,	PUNCT
admet-839	88	10	2	2	NUM
admet-839	88	11	,	,	PUNCT
admet-839	88	12	4	4	NUM
admet-839	88	13	,	,	PUNCT
admet-839	88	14	7	7	NUM
admet-839	88	15	,	,	PUNCT
admet-839	88	16	10	10	NUM
admet-839	88	17	,	,	PUNCT
admet-839	88	18	14	14	NUM
admet-839	88	19	,	,	PUNCT
admet-839	88	20	17	17	NUM
admet-839	88	21	,	,	PUNCT
admet-839	88	22	21	21	NUM
admet-839	88	23	,	,	PUNCT
admet-839	88	24	25	25	NUM
admet-839	88	25	,	,	PUNCT
admet-839	88	26	29	29	NUM
admet-839	88	27	,	,	PUNCT
admet-839	88	28	32	32	NUM
admet-839	88	29	,	,	PUNCT
admet-839	88	30	38	38	NUM
admet-839	88	31	,	,	PUNCT
admet-839	88	32	44	44	NUM
admet-839	88	33	,	,	PUNCT
admet-839	88	34	53	53	NUM
admet-839	88	35	,	,	PUNCT
admet-839	88	36	60	60	NUM
admet-839	88	37	and	and	CCONJ
admet-839	88	38	80	80	NUM
admet-839	88	39	)	)	PUNCT
admet-839	88	40	three	three	NUM
admet-839	88	41	samples	sample	NOUN
admet-839	88	42	were	be	AUX
admet-839	88	43	extracted	extract	VERB
admet-839	88	44	from	from	ADP
admet-839	88	45	opposite	opposite	ADJ
admet-839	88	46	sides	side	NOUN
admet-839	88	47	of	of	ADP
admet-839	88	48	the	the	DET
admet-839	88	49	xrpd	xrpd	PROPN
admet-839	88	50	sample	sample	NOUN
admet-839	88	51	holder	holder	NOUN
admet-839	88	52	and	and	CCONJ
admet-839	88	53	never	never	ADV
admet-839	88	54	from	from	ADP
admet-839	88	55	the	the	DET
admet-839	88	56	same	same	ADJ
admet-839	88	57	location	location	NOUN
admet-839	88	58	twice	twice	ADV
admet-839	88	59	.	.	PUNCT
admet-839	89	1	the	the	DET
admet-839	89	2	xrpd	xrpd	PROPN
admet-839	89	3	scan	scan	PROPN
admet-839	89	4	area	area	PROPN
admet-839	89	5	was	be	AUX
admet-839	89	6	left	leave	VERB
admet-839	89	7	intact	intact	ADJ
admet-839	89	8	in	in	ADP
admet-839	89	9	order	order	NOUN
admet-839	89	10	for	for	ADP
admet-839	89	11	sampling	sample	VERB
admet-839	89	12	not	not	PART
admet-839	89	13	to	to	PART
admet-839	89	14	affect	affect	VERB
admet-839	89	15	the	the	DET
admet-839	89	16	xrpd	xrpd	PROPN
admet-839	89	17	signal	signal	NOUN
admet-839	89	18	.	.	PUNCT
admet-839	90	1	an	an	DET
admet-839	90	2	aqueous	aqueous	ADJ
admet-839	90	3	solution	solution	NOUN
admet-839	90	4	of	of	ADP
admet-839	90	5	hcl	hcl	PROPN
admet-839	90	6	ph	ph	PROPN
admet-839	90	7	2.0	2.0	NUM
admet-839	90	8	was	be	AUX
admet-839	90	9	used	use	VERB
admet-839	90	10	as	as	ADP
admet-839	90	11	a	a	DET
admet-839	90	12	solvent	solvent	NOUN
admet-839	90	13	.	.	PUNCT
admet-839	91	1	separately	separately	ADV
admet-839	91	2	,	,	PUNCT
admet-839	91	3	crystalline	crystalline	NOUN
admet-839	91	4	samples	sample	NOUN
admet-839	91	5	of	of	ADP
admet-839	91	6	α	α	NOUN
admet-839	91	7	and	and	CCONJ
admet-839	91	8	γ	γ	PROPN
admet-839	91	9	indomethacin	indomethacin	PROPN
admet-839	91	10	were	be	AUX
admet-839	91	11	also	also	ADV
admet-839	91	12	measured	measure	VERB
admet-839	91	13	with	with	ADP
admet-839	91	14	the	the	DET
admet-839	91	15	spa	spa	NOUN
admet-839	91	16	method	method	NOUN
admet-839	91	17	.	.	PUNCT
admet-839	92	1	the	the	DET
admet-839	92	2	spa	spa	NOUN
admet-839	92	3	methodology	methodology	NOUN
admet-839	92	4	has	have	AUX
admet-839	92	5	already	already	ADV
admet-839	92	6	been	be	AUX
admet-839	92	7	previously	previously	ADV
admet-839	92	8	described	describe	VERB
admet-839	92	9	by	by	ADP
admet-839	92	10	svanbäck	svanbäck	PROPN
admet-839	92	11	et	et	PROPN
admet-839	92	12	al	al	PROPN
admet-839	92	13	.	.	PROPN
admet-839	93	1	and	and	CCONJ
admet-839	93	2	štukelj	štukelj	PROPN
admet-839	93	3	et	et	PROPN
admet-839	93	4	al	al	PROPN
admet-839	93	5	.	.	PUNCT
admet-839	94	1	[	[	X
admet-839	94	2	17,18,22	17,18,22	NUM
admet-839	94	3	]	]	X
admet-839	94	4	.	.	PUNCT
admet-839	95	1	shortly	shortly	ADV
admet-839	95	2	,	,	PUNCT
admet-839	95	3	the	the	DET
admet-839	95	4	spa	spa	NOUN
admet-839	95	5	is	be	AUX
admet-839	95	6	comprised	comprise	VERB
admet-839	95	7	of	of	ADP
admet-839	95	8	two	two	NUM
admet-839	95	9	prime	prime	ADJ
admet-839	95	10	components	component	NOUN
admet-839	95	11	–	–	PUNCT
admet-839	95	12	the	the	DET
admet-839	95	13	flow	flow	NOUN
admet-839	95	14	-	-	PUNCT
admet-839	95	15	through	through	ADP
admet-839	95	16	setup	setup	NOUN
admet-839	95	17	and	and	CCONJ
admet-839	95	18	the	the	DET
admet-839	95	19	custom	custom	ADV
admet-839	95	20	-	-	PUNCT
admet-839	95	21	made	make	VERB
admet-839	95	22	analysis	analysis	NOUN
admet-839	95	23	software	software	NOUN
admet-839	95	24	(	(	PUNCT
admet-839	95	25	figure	figure	NOUN
admet-839	95	26	1a	1a	NOUN
admet-839	95	27	)	)	PUNCT
admet-839	95	28	.	.	PUNCT
admet-839	96	1	the	the	DET
admet-839	96	2	flow	flow	NOUN
admet-839	96	3	-	-	PUNCT
admet-839	96	4	through	through	ADP
admet-839	96	5	setup	setup	NOUN
admet-839	96	6	is	be	AUX
admet-839	96	7	capable	capable	ADJ
admet-839	96	8	of	of	ADP
admet-839	96	9	immobilizing	immobilize	VERB
admet-839	96	10	the	the	DET
admet-839	96	11	drug	drug	NOUN
admet-839	96	12	particles	particle	NOUN
admet-839	96	13	under	under	ADP
admet-839	96	14	steady	steady	ADJ
admet-839	96	15	flow	flow	NOUN
admet-839	96	16	.	.	PUNCT
admet-839	97	1	immobilized	immobilized	ADJ
admet-839	97	2	particles	particle	NOUN
admet-839	97	3	are	be	AUX
admet-839	97	4	imaged	image	VERB
admet-839	97	5	as	as	SCONJ
admet-839	97	6	they	they	PRON
admet-839	97	7	dissolve	dissolve	VERB
admet-839	97	8	–	–	PUNCT
admet-839	97	9	reduce	reduce	VERB
admet-839	97	10	in	in	ADP
admet-839	97	11	size	size	NOUN
admet-839	97	12	.	.	PUNCT
admet-839	98	1	in	in	ADP
admet-839	98	2	this	this	DET
admet-839	98	3	study	study	NOUN
admet-839	98	4	,	,	PUNCT
admet-839	98	5	each	each	DET
admet-839	98	6	measurement	measurement	NOUN
admet-839	98	7	took	take	VERB
admet-839	98	8	roughly	roughly	ADV
admet-839	98	9	5	5	NUM
admet-839	98	10	minutes	minute	NOUN
admet-839	98	11	.	.	PUNCT
admet-839	99	1	captured	capture	VERB
admet-839	99	2	images	image	NOUN
admet-839	99	3	of	of	ADP
admet-839	99	4	the	the	DET
admet-839	99	5	particles	particle	NOUN
admet-839	99	6	are	be	AUX
admet-839	99	7	analysed	analyse	VERB
admet-839	99	8	using	use	VERB
admet-839	99	9	the	the	DET
admet-839	99	10	custom	custom	ADV
admet-839	99	11	-	-	PUNCT
admet-839	99	12	made	make	VERB
admet-839	99	13	software	software	NOUN
admet-839	99	14	,	,	PUNCT
admet-839	99	15	which	which	PRON
admet-839	99	16	tracks	track	VERB
admet-839	99	17	the	the	DET
admet-839	99	18	reduction	reduction	NOUN
admet-839	99	19	in	in	ADP
admet-839	99	20	particle	particle	NOUN
admet-839	99	21	morphology	morphology	NOUN
admet-839	99	22	throughout	throughout	ADP
admet-839	99	23	the	the	DET
admet-839	99	24	course	course	NOUN
admet-839	99	25	of	of	ADP
admet-839	99	26	a	a	DET
admet-839	99	27	measurement	measurement	NOUN
admet-839	99	28	.	.	PUNCT
admet-839	100	1	the	the	DET
admet-839	100	2	decrease	decrease	NOUN
admet-839	100	3	in	in	ADP
admet-839	100	4	mass	mass	NOUN
admet-839	100	5	over	over	ADP
admet-839	100	6	time	time	NOUN
admet-839	100	7	or	or	CCONJ
admet-839	100	8	dissolution	dissolution	NOUN
admet-839	100	9	rate	rate	NOUN
admet-839	100	10	(	(	PUNCT
admet-839	100	11	dm	dm	PROPN
admet-839	100	12	/	/	SYM
admet-839	100	13	dt	dt	NOUN
admet-839	100	14	)	)	PUNCT
admet-839	100	15	under	under	ADP
admet-839	100	16	sink	sink	NOUN
admet-839	100	17	conditions	condition	NOUN
admet-839	100	18	(	(	PUNCT
admet-839	100	19	when	when	SCONJ
admet-839	100	20	the	the	DET
admet-839	100	21	bulk	bulk	ADJ
admet-839	100	22	concentration	concentration	NOUN
admet-839	100	23	(	(	PUNCT
admet-839	100	24	cb	cb	NOUN
admet-839	100	25	)	)	PUNCT
admet-839	100	26	can	can	AUX
admet-839	100	27	be	be	AUX
admet-839	100	28	assumed	assume	VERB
admet-839	100	29	to	to	PART
admet-839	100	30	be	be	AUX
admet-839	100	31	zero	zero	NUM
admet-839	100	32	)	)	PUNCT
admet-839	100	33	is	be	AUX
admet-839	100	34	,	,	PUNCT
admet-839	100	35	according	accord	VERB
admet-839	100	36	to	to	ADP
admet-839	100	37	noyes	noyes	PROPN
admet-839	100	38	and	and	CCONJ
admet-839	100	39	whitney	whitney	PROPN
admet-839	100	40	(	(	PUNCT
admet-839	100	41	eq	eq	NOUN
admet-839	100	42	.	.	PROPN
admet-839	100	43	1	1	NUM
admet-839	100	44	)	)	PUNCT
admet-839	100	45	,	,	PUNCT
admet-839	100	46	directly	directly	ADV
admet-839	100	47	proportional	proportional	ADJ
admet-839	100	48	to	to	ADP
admet-839	100	49	the	the	DET
admet-839	100	50	equilibrium	equilibrium	NOUN
admet-839	100	51	solubility	solubility	NOUN
admet-839	100	52	(	(	PUNCT
admet-839	100	53	cs	cs	PROPN
admet-839	100	54	)	)	PUNCT
admet-839	100	55	of	of	ADP
admet-839	100	56	a	a	DET
admet-839	100	57	compound	compound	NOUN
admet-839	100	58	.	.	PUNCT
admet-839	101	1	the	the	DET
admet-839	101	2	setup	setup	NOUN
admet-839	101	3	-	-	PUNCT
admet-839	101	4	dependent	dependent	ADJ
admet-839	101	5	-	-	PUNCT
admet-839	101	6	transport	transport	NOUN
admet-839	101	7	-	-	PUNCT
admet-839	101	8	rate	rate	NOUN
admet-839	101	9	constant	constant	ADJ
admet-839	101	10	(	(	PUNCT
admet-839	101	11	k	k	NOUN
admet-839	101	12	)	)	PUNCT
admet-839	101	13	is	be	AUX
admet-839	101	14	determined	determine	VERB
admet-839	101	15	as	as	SCONJ
admet-839	101	16	described	describe	VERB
admet-839	101	17	by	by	ADP
admet-839	101	18	svanbäck	svanbäck	PROPN
admet-839	101	19	et	et	PROPN
admet-839	101	20	al	al	PROPN
admet-839	101	21	.	.	PUNCT
admet-839	102	1	[	[	X
admet-839	102	2	23	23	NUM
admet-839	102	3	]	]	PUNCT
admet-839	102	4	.	.	PUNCT
admet-839	103	1	furthermore	furthermore	ADV
admet-839	103	2	,	,	PUNCT
admet-839	103	3	if	if	SCONJ
admet-839	103	4	the	the	DET
admet-839	103	5	compound	compound	NOUN
admet-839	103	6	is	be	AUX
admet-839	103	7	in	in	ADP
admet-839	103	8	its	its	PRON
admet-839	103	9	most	most	ADV
admet-839	103	10	stable	stable	ADJ
admet-839	103	11	crystalline	crystalline	NOUN
admet-839	103	12	form	form	NOUN
admet-839	103	13	,	,	PUNCT
admet-839	103	14	the	the	DET
admet-839	103	15	determined	determined	ADJ
admet-839	103	16	equilibrium	equilibrium	NOUN
admet-839	103	17	solubility	solubility	NOUN
admet-839	103	18	corresponds	correspond	VERB
admet-839	103	19	to	to	ADP
admet-839	103	20	the	the	DET
admet-839	103	21	thermodynamic	thermodynamic	ADJ
admet-839	103	22	equilibrium	equilibrium	NOUN
admet-839	103	23	solubility	solubility	NOUN
admet-839	103	24	of	of	ADP
admet-839	103	25	a	a	DET
admet-839	103	26	compound	compound	NOUN
admet-839	103	27	.	.	PUNCT
admet-839	104	1	on	on	ADP
admet-839	104	2	the	the	DET
admet-839	104	3	other	other	ADJ
admet-839	104	4	hand	hand	NOUN
admet-839	104	5	,	,	PUNCT
admet-839	104	6	for	for	ADP
admet-839	104	7	a	a	DET
admet-839	104	8	purely	purely	ADV
admet-839	104	9	amorphous	amorphous	ADJ
admet-839	104	10	sample	sample	NOUN
admet-839	104	11	,	,	PUNCT
admet-839	104	12	in	in	ADP
admet-839	104	13	the	the	DET
admet-839	104	14	absence	absence	NOUN
admet-839	104	15	of	of	ADP
admet-839	104	16	crystallisation	crystallisation	NOUN
admet-839	104	17	during	during	ADP
admet-839	104	18	the	the	DET
admet-839	104	19	spa	spa	NOUN
admet-839	104	20	measurement	measurement	NOUN
admet-839	104	21	,	,	PUNCT
admet-839	104	22	the	the	DET
admet-839	104	23	measured	measured	ADJ
admet-839	104	24	solubility	solubility	NOUN
admet-839	104	25	is	be	AUX
admet-839	104	26	actually	actually	ADV
admet-839	104	27	the	the	DET
admet-839	104	28	amorphous	amorphous	ADJ
admet-839	104	29	solubility	solubility	NOUN
admet-839	104	30	–	–	PUNCT
admet-839	104	31	the	the	DET
admet-839	104	32	maximum	maximum	ADJ
admet-839	104	33	drug	drug	NOUN
admet-839	104	34	concentration	concentration	NOUN
admet-839	104	35	in	in	ADP
admet-839	104	36	solution	solution	NOUN
admet-839	104	37	upon	upon	SCONJ
admet-839	104	38	dissolution	dissolution	NOUN
admet-839	104	39	of	of	ADP
admet-839	104	40	an	an	DET
admet-839	104	41	amorphous	amorphous	ADJ
admet-839	104	42	solid	solid	NOUN
admet-839	104	43	.	.	PUNCT
admet-839	105	1	the	the	DET
admet-839	105	2	approach	approach	NOUN
admet-839	105	3	of	of	ADP
admet-839	105	4	measuring	measure	VERB
admet-839	105	5	amorphous	amorphous	ADJ
admet-839	105	6	solubility	solubility	NOUN
admet-839	105	7	using	use	VERB
admet-839	105	8	the	the	DET
admet-839	105	9	spa	spa	NOUN
admet-839	105	10	technology	technology	NOUN
admet-839	105	11	was	be	AUX
admet-839	105	12	recently	recently	ADV
admet-839	105	13	validated	validate	VERB
admet-839	105	14	by	by	ADP
admet-839	105	15	štukelj	štukelj	PROPN
admet-839	105	16	et	et	PROPN
admet-839	105	17	al	al	PROPN
admet-839	105	18	.	.	PROPN
admet-839	106	1	(	(	PUNCT
admet-839	106	2	2019	2019	NUM
admet-839	106	3	)	)	PUNCT
admet-839	106	4	,	,	PUNCT
admet-839	106	5	admet	admet	PROPN
admet-839	106	6	&	&	CCONJ
admet-839	106	7	dmpk	dmpk	PROPN
admet-839	106	8	8(4	8(4	NOUN
admet-839	106	9	)	)	PUNCT
admet-839	106	10	(	(	PUNCT
admet-839	106	11	2020	2020	NUM
admet-839	106	12	)	)	PUNCT
admet-839	106	13	401	401	NUM
admet-839	106	14	-	-	SYM
admet-839	106	15	409	409	NUM
admet-839	106	16	amorphous	amorphous	ADJ
admet-839	106	17	solubility	solubility	NOUN
admet-839	106	18	over	over	ADP
admet-839	106	19	time	time	NOUN
admet-839	106	20	doi	doi	PROPN
admet-839	106	21	:	:	PUNCT
admet-839	106	22	https://dx.doi.org/10.5599/admet.839	https://dx.doi.org/10.5599/admet.839	NOUN
admet-839	106	23	405	405	NUM
admet-839	106	24	with	with	ADP
admet-839	106	25	the	the	DET
admet-839	106	26	amorphous	amorphous	ADJ
admet-839	106	27	solubility	solubility	NOUN
admet-839	106	28	of	of	ADP
admet-839	106	29	five	five	NUM
admet-839	106	30	diverse	diverse	ADJ
admet-839	106	31	compounds	compound	NOUN
admet-839	106	32	being	be	AUX
admet-839	106	33	assessed	assess	VERB
admet-839	106	34	by	by	ADP
admet-839	106	35	spa	spa	NOUN
admet-839	106	36	and	and	CCONJ
admet-839	106	37	two	two	NUM
admet-839	106	38	orthogonal	orthogonal	ADJ
admet-839	106	39	methods	method	NOUN
admet-839	106	40	:	:	PUNCT
admet-839	106	41	standardized	standardized	ADJ
admet-839	106	42	supersaturation	supersaturation	NOUN
admet-839	106	43	and	and	CCONJ
admet-839	106	44	precipitation	precipitation	NOUN
admet-839	106	45	,	,	PUNCT
admet-839	106	46	and	and	CCONJ
admet-839	106	47	theoretical	theoretical	ADJ
admet-839	106	48	estimation	estimation	NOUN
admet-839	106	49	based	base	VERB
admet-839	106	50	on	on	ADP
admet-839	106	51	thermal	thermal	ADJ
admet-839	106	52	analysis	analysis	NOUN
admet-839	107	1	[	[	X
admet-839	107	2	18	18	NUM
admet-839	107	3	]	]	PUNCT
admet-839	107	4	.	.	PUNCT
admet-839	108	1			NOUN
admet-839	109	1	s	s	PROPN
admet-839	109	2	b	b	NOUN
admet-839	109	3	s	s	PROPN
admet-839	109	4	d	d	X
admet-839	109	5	d	d	PROPN
admet-839	109	6	d	d	PROPN
admet-839	109	7	d	d	X
admet-839	109	8	m	m	VERB
admet-839	109	9	m	m	VERB
admet-839	109	10	k	k	X
admet-839	109	11	c	c	PROPN
admet-839	109	12	c	c	PROPN
admet-839	109	13	kc	kc	PROPN
admet-839	109	14	t	t	PROPN
admet-839	109	15	t	t	PROPN
admet-839	109	16			PROPN
admet-839	109	17			PROPN
admet-839	109	18			NOUN
admet-839	109	19			NOUN
admet-839	109	20			ADJ
admet-839	109	21			NOUN
admet-839	109	22	(	(	PUNCT
admet-839	109	23	1	1	NUM
admet-839	109	24	)	)	PUNCT
admet-839	109	25	results	result	NOUN
admet-839	109	26	and	and	CCONJ
admet-839	109	27	discussion	discussion	NOUN
admet-839	109	28	characterization	characterization	NOUN
admet-839	109	29	of	of	ADP
admet-839	109	30	the	the	DET
admet-839	109	31	initial	initial	ADJ
admet-839	109	32	solid	solid	ADJ
admet-839	109	33	-	-	PUNCT
admet-839	109	34	state	state	NOUN
admet-839	109	35	form	form	NOUN
admet-839	109	36	the	the	DET
admet-839	109	37	dsc	dsc	NOUN
admet-839	109	38	thermograms	thermogram	NOUN
admet-839	109	39	of	of	ADP
admet-839	109	40	the	the	DET
admet-839	109	41	amorphous	amorphous	ADJ
admet-839	109	42	and	and	CCONJ
admet-839	109	43	two	two	NUM
admet-839	109	44	crystalline	crystalline	NOUN
admet-839	109	45	indomethacin	indomethacin	NOUN
admet-839	109	46	forms	form	NOUN
admet-839	109	47	are	be	AUX
admet-839	109	48	presented	present	VERB
admet-839	109	49	in	in	ADP
admet-839	109	50	figure	figure	NOUN
admet-839	109	51	2a	2a	NUM
admet-839	109	52	.	.	PUNCT
admet-839	110	1	the	the	DET
admet-839	110	2	amorphous	amorphous	ADJ
admet-839	110	3	thermogram	thermogram	NOUN
admet-839	110	4	exhibits	exhibit	VERB
admet-839	110	5	a	a	DET
admet-839	110	6	glass	glass	NOUN
admet-839	110	7	transition	transition	NOUN
admet-839	110	8	mid	mid	NOUN
admet-839	110	9	-	-	NOUN
admet-839	110	10	point	point	NOUN
admet-839	110	11	at	at	ADP
admet-839	110	12	44.2	44.2	NUM
admet-839	110	13	±	±	NUM
admet-839	110	14	1.0	1.0	NUM
admet-839	110	15	°	°	ADP
admet-839	110	16	c	c	NOUN
admet-839	110	17	,	,	PUNCT
admet-839	110	18	a	a	DET
admet-839	110	19	crystallization	crystallization	NOUN
admet-839	110	20	onset	onset	NOUN
admet-839	110	21	at	at	ADP
admet-839	110	22	99.5	99.5	NUM
admet-839	110	23	±	±	NUM
admet-839	110	24	0.2	0.2	NUM
admet-839	110	25	°	°	ADP
admet-839	110	26	c	c	NOUN
admet-839	110	27	,	,	PUNCT
admet-839	110	28	a	a	DET
admet-839	110	29	melting	melting	NOUN
admet-839	110	30	peak	peak	NOUN
admet-839	110	31	onset	onset	NOUN
admet-839	110	32	corresponding	correspond	VERB
admet-839	110	33	to	to	ADP
admet-839	110	34	the	the	DET
admet-839	110	35	α	α	PROPN
admet-839	110	36	form	form	NOUN
admet-839	110	37	at	at	ADP
admet-839	110	38	153.2	153.2	NUM
admet-839	110	39	±	±	NUM
admet-839	110	40	0.1	0.1	NUM
admet-839	110	41	°	°	ADP
admet-839	110	42	c	c	NOUN
admet-839	110	43	and	and	CCONJ
admet-839	110	44	a	a	DET
admet-839	110	45	melting	melting	NOUN
admet-839	110	46	peak	peak	NOUN
admet-839	110	47	onset	onset	NOUN
admet-839	110	48	corresponding	correspond	VERB
admet-839	110	49	to	to	ADP
admet-839	110	50	the	the	DET
admet-839	110	51	γ	γ	PROPN
admet-839	110	52	form	form	NOUN
admet-839	110	53	at	at	ADP
admet-839	110	54	159.8	159.8	NUM
admet-839	110	55	±	±	NUM
admet-839	110	56	0.1	0.1	NUM
admet-839	110	57	°	°	SYM
admet-839	110	58	c	c	NOUN
admet-839	110	59	.	.	PUNCT
admet-839	111	1	crystallization	crystallization	NOUN
admet-839	111	2	of	of	ADP
admet-839	111	3	freshly	freshly	ADV
admet-839	111	4	-	-	PUNCT
admet-839	111	5	prepared	prepare	VERB
admet-839	111	6	melted	melt	VERB
admet-839	111	7	and	and	CCONJ
admet-839	111	8	cooled	cool	VERB
admet-839	111	9	amorphous	amorphous	ADJ
admet-839	111	10	indomethacin	indomethacin	NOUN
admet-839	111	11	during	during	ADP
admet-839	111	12	heating	heating	NOUN
admet-839	111	13	to	to	ADP
admet-839	111	14	both	both	DET
admet-839	111	15	these	these	DET
admet-839	111	16	forms	form	NOUN
admet-839	111	17	has	have	AUX
admet-839	111	18	been	be	AUX
admet-839	111	19	observed	observe	VERB
admet-839	111	20	earlier	early	ADV
admet-839	111	21	[	[	X
admet-839	111	22	13,24	13,24	X
admet-839	111	23	]	]	X
admet-839	111	24	.	.	PUNCT
admet-839	112	1	the	the	DET
admet-839	112	2	thermogram	thermogram	NOUN
admet-839	112	3	of	of	ADP
admet-839	112	4	the	the	DET
admet-839	112	5	γ	γ	PROPN
admet-839	112	6	form	form	NOUN
admet-839	112	7	exhibits	exhibit	VERB
admet-839	112	8	a	a	DET
admet-839	112	9	melting	melting	NOUN
admet-839	112	10	peak	peak	NOUN
admet-839	112	11	at	at	ADP
admet-839	112	12	159.8	159.8	NUM
admet-839	112	13	±	±	NUM
admet-839	112	14	0.2	0.2	NUM
admet-839	112	15	°	°	ADP
admet-839	112	16	c	c	NOUN
admet-839	112	17	and	and	CCONJ
admet-839	112	18	the	the	DET
admet-839	112	19	thermogram	thermogram	NOUN
admet-839	112	20	of	of	ADP
admet-839	112	21	the	the	DET
admet-839	112	22	α	α	PROPN
admet-839	112	23	form	form	NOUN
admet-839	112	24	exhibits	exhibit	VERB
admet-839	112	25	a	a	DET
admet-839	112	26	melting	melting	NOUN
admet-839	112	27	peak	peak	NOUN
admet-839	112	28	at	at	ADP
admet-839	112	29	152.7	152.7	NUM
admet-839	112	30	±	±	NUM
admet-839	112	31	0.2	0.2	NUM
admet-839	112	32	°	°	SYM
admet-839	112	33	c	c	NOUN
admet-839	112	34	.	.	PUNCT
admet-839	113	1	the	the	DET
admet-839	113	2	xrpd	xrpd	PROPN
admet-839	113	3	diffractogram	diffractogram	PROPN
admet-839	113	4	of	of	ADP
admet-839	113	5	the	the	DET
admet-839	113	6	amorphous	amorphous	ADJ
admet-839	113	7	sample	sample	NOUN
admet-839	113	8	exhibits	exhibit	VERB
admet-839	113	9	a	a	DET
admet-839	113	10	distinctive	distinctive	ADJ
admet-839	113	11	amorphous	amorphous	ADJ
admet-839	113	12	halo	halo	NOUN
admet-839	113	13	and	and	CCONJ
admet-839	113	14	is	be	AUX
admet-839	113	15	devoid	devoid	ADJ
admet-839	113	16	of	of	ADP
admet-839	113	17	any	any	DET
admet-839	113	18	peaks	peak	NOUN
admet-839	113	19	that	that	PRON
admet-839	113	20	would	would	AUX
admet-839	113	21	indicate	indicate	VERB
admet-839	113	22	crystallinity	crystallinity	NOUN
admet-839	113	23	(	(	PUNCT
admet-839	113	24	figure	figure	NOUN
admet-839	113	25	2b	2b	NOUN
admet-839	113	26	)	)	PUNCT
admet-839	114	1	[	[	X
admet-839	114	2	13	13	NUM
admet-839	114	3	]	]	PUNCT
admet-839	114	4	.	.	PUNCT
admet-839	115	1	the	the	DET
admet-839	115	2	diffractograms	diffractogram	NOUN
admet-839	115	3	of	of	ADP
admet-839	115	4	the	the	DET
admet-839	115	5	α	α	NOUN
admet-839	115	6	and	and	CCONJ
admet-839	115	7	γ	γ	PROPN
admet-839	115	8	crystalline	crystalline	NOUN
admet-839	115	9	samples	sample	NOUN
admet-839	115	10	match	match	VERB
admet-839	115	11	the	the	DET
admet-839	115	12	predicted	predict	VERB
admet-839	115	13	diffractograms	diffractogram	NOUN
admet-839	115	14	of	of	ADP
admet-839	115	15	the	the	DET
admet-839	115	16	respective	respective	ADJ
admet-839	115	17	forms	form	NOUN
admet-839	115	18	(	(	PUNCT
admet-839	115	19	indmet02	indmet02	ADJ
admet-839	115	20	and	and	CCONJ
admet-839	115	21	indmet01	indmet01	NOUN
admet-839	115	22	)	)	PUNCT
admet-839	115	23	from	from	ADP
admet-839	115	24	the	the	DET
admet-839	115	25	cambridge	cambridge	PROPN
admet-839	115	26	structural	structural	PROPN
admet-839	115	27	database	database	NOUN
admet-839	115	28	.	.	PUNCT
admet-839	116	1	figure	figure	NOUN
admet-839	116	2	2	2	NUM
admet-839	116	3	.	.	PUNCT
admet-839	117	1	(	(	PUNCT
admet-839	117	2	a	a	X
admet-839	117	3	)	)	PUNCT
admet-839	117	4	thermograms	thermogram	NOUN
admet-839	117	5	of	of	ADP
admet-839	117	6	α	α	PRON
admet-839	117	7	,	,	PUNCT
admet-839	117	8	γ	γ	X
admet-839	117	9	and	and	CCONJ
admet-839	117	10	amorphous	amorphous	ADJ
admet-839	117	11	indomethacin	indomethacin	NOUN
admet-839	117	12	samples	sample	NOUN
admet-839	117	13	.	.	PUNCT
admet-839	118	1	(	(	PUNCT
admet-839	118	2	b	b	X
admet-839	118	3	)	)	PUNCT
admet-839	118	4	diffractograms	diffractogram	NOUN
admet-839	118	5	of	of	ADP
admet-839	118	6	α	α	PRON
admet-839	118	7	,	,	PUNCT
admet-839	118	8	γ	γ	X
admet-839	118	9	and	and	CCONJ
admet-839	118	10	amorphous	amorphous	ADJ
admet-839	118	11	indomethacin	indomethacin	NOUN
admet-839	118	12	samples	sample	NOUN
admet-839	118	13	.	.	PUNCT
admet-839	119	1	solubility	solubility	NOUN
admet-839	119	2	of	of	ADP
admet-839	119	3	α	α	PROPN
admet-839	119	4	and	and	CCONJ
admet-839	119	5	γ	γ	PROPN
admet-839	119	6	indomethacin	indomethacin	VERB
admet-839	119	7	the	the	DET
admet-839	119	8	intrinsic	intrinsic	ADJ
admet-839	119	9	solubility	solubility	NOUN
admet-839	119	10	of	of	ADP
admet-839	119	11	α	α	PROPN
admet-839	119	12	and	and	CCONJ
admet-839	119	13	γ	γ	PROPN
admet-839	119	14	indomethacin	indomethacin	NOUN
admet-839	119	15	measured	measure	VERB
admet-839	119	16	using	use	VERB
admet-839	119	17	the	the	DET
admet-839	119	18	spa	spa	NOUN
admet-839	119	19	method	method	NOUN
admet-839	119	20	is	be	AUX
admet-839	119	21	compared	compare	VERB
admet-839	119	22	to	to	ADP
admet-839	119	23	the	the	DET
admet-839	119	24	intrinsic	intrinsic	ADJ
admet-839	119	25	solubility	solubility	NOUN
admet-839	119	26	of	of	ADP
admet-839	119	27	these	these	DET
admet-839	119	28	two	two	NUM
admet-839	119	29	forms	form	NOUN
admet-839	119	30	as	as	SCONJ
admet-839	119	31	assessed	assess	VERB
admet-839	119	32	using	use	VERB
admet-839	119	33	the	the	DET
admet-839	119	34	orthogonal	orthogonal	ADJ
admet-839	119	35	methods	method	NOUN
admet-839	119	36	in	in	ADP
admet-839	119	37	table	table	NOUN
admet-839	119	38	1	1	NUM
admet-839	119	39	.	.	PUNCT
admet-839	120	1	the	the	DET
admet-839	120	2	intrinsic	intrinsic	ADJ
admet-839	120	3	solubility	solubility	NOUN
admet-839	120	4	of	of	ADP
admet-839	120	5	the	the	DET
admet-839	120	6	α	α	PROPN
admet-839	120	7	form	form	NOUN
admet-839	120	8	was	be	AUX
admet-839	120	9	measured	measure	VERB
admet-839	120	10	previously	previously	ADV
admet-839	120	11	by	by	ADP
admet-839	120	12	surwase	surwase	PROPN
admet-839	120	13	et	et	PROPN
admet-839	120	14	al	al	PROPN
admet-839	120	15	.	.	PUNCT
admet-839	120	16	using	use	VERB
admet-839	120	17	a	a	DET
admet-839	120	18	shake	shake	NOUN
admet-839	120	19	-	-	PUNCT
admet-839	120	20	flask	flask	NOUN
admet-839	120	21	method	method	NOUN
admet-839	120	22	[	[	X
admet-839	120	23	20	20	NUM
admet-839	120	24	]	]	PUNCT
admet-839	120	25	.	.	PUNCT
admet-839	121	1	the	the	DET
admet-839	121	2	intrinsic	intrinsic	ADJ
admet-839	121	3	solubility	solubility	NOUN
admet-839	121	4	of	of	ADP
admet-839	121	5	the	the	DET
admet-839	121	6	γ	γ	PROPN
admet-839	121	7	form	form	NOUN
admet-839	121	8	was	be	AUX
admet-839	121	9	measured	measure	VERB
admet-839	121	10	by	by	ADP
admet-839	121	11	štukelj	štukelj	PROPN
admet-839	121	12	et	et	PROPN
admet-839	121	13	al	al	PROPN
admet-839	121	14	.	.	PUNCT
admet-839	121	15	using	use	VERB
admet-839	121	16	a	a	DET
admet-839	121	17	µdiss	µdiss	NOUN
admet-839	121	18	profiler	profiler	NOUN
admet-839	121	19	™	™	PUNCT
admet-839	121	20	[	[	X
admet-839	121	21	18	18	NUM
admet-839	121	22	]	]	PUNCT
admet-839	121	23	.	.	PUNCT
admet-839	122	1	the	the	DET
admet-839	122	2	obtained	obtain	VERB
admet-839	122	3	values	value	NOUN
admet-839	122	4	are	be	AUX
admet-839	122	5	in	in	ADP
admet-839	122	6	good	good	ADJ
admet-839	122	7	agreement	agreement	NOUN
admet-839	122	8	and	and	CCONJ
admet-839	122	9	within	within	ADP
admet-839	122	10	the	the	DET
admet-839	122	11	generally	generally	ADV
admet-839	122	12	accepted	accept	VERB
admet-839	122	13	average	average	ADJ
admet-839	122	14	uncertainty	uncertainty	NOUN
admet-839	122	15	in	in	ADP
admet-839	122	16	experimental	experimental	ADJ
admet-839	122	17	solubility	solubility	NOUN
admet-839	122	18	measurements	measurement	NOUN
admet-839	122	19	of	of	ADP
admet-839	122	20	0.6	0.6	NUM
admet-839	122	21	log	log	NOUN
admet-839	122	22	units	unit	NOUN
admet-839	122	23	[	[	X
admet-839	122	24	25	25	NUM
admet-839	122	25	]	]	PUNCT
admet-839	122	26	.	.	PUNCT
admet-839	123	1	table	table	NOUN
admet-839	123	2	1	1	NUM
admet-839	123	3	.	.	PUNCT
admet-839	123	4	intrinsic	intrinsic	ADJ
admet-839	123	5	solubilities	solubility	NOUN
admet-839	123	6	of	of	ADP
admet-839	123	7	α	α	PROPN
admet-839	123	8	and	and	CCONJ
admet-839	123	9	γ	γ	PROPN
admet-839	123	10	indomethacin	indomethacin	NOUN
admet-839	123	11	measured	measure	VERB
admet-839	123	12	with	with	ADP
admet-839	123	13	the	the	DET
admet-839	123	14	spa	spa	NOUN
admet-839	123	15	method	method	NOUN
admet-839	123	16	compared	compare	VERB
admet-839	123	17	to	to	ADP
admet-839	123	18	previously	previously	ADV
admet-839	123	19	determined	determine	VERB
admet-839	123	20	intrinsic	intrinsic	ADJ
admet-839	123	21	solubility	solubility	NOUN
admet-839	123	22	values	value	NOUN
admet-839	123	23	using	use	VERB
admet-839	123	24	the	the	DET
admet-839	123	25	shake	shake	NOUN
admet-839	123	26	-	-	PUNCT
admet-839	123	27	flask	flask	NOUN
admet-839	123	28	(	(	PUNCT
admet-839	123	29	α	α	NOUN
admet-839	123	30	form	form	NOUN
admet-839	123	31	)	)	PUNCT
admet-839	123	32	and	and	CCONJ
admet-839	123	33	µdiss	µdiss	NOUN
admet-839	123	34	profiler	profiler	NOUN
admet-839	123	35	™	™	PUNCT
admet-839	123	36	(	(	PUNCT
admet-839	123	37	γ	γ	NOUN
admet-839	123	38	form	form	NOUN
admet-839	123	39	)	)	PUNCT
admet-839	123	40	methods	method	NOUN
admet-839	123	41	.	.	PUNCT
admet-839	124	1	intrinsic	intrinsic	ADJ
admet-839	124	2	solubility	solubility	NOUN
admet-839	124	3	(	(	PUNCT
admet-839	124	4	µg	µg	NOUN
admet-839	124	5	/	/	SYM
admet-839	124	6	ml	ml	NOUN
admet-839	124	7	)	)	PUNCT
admet-839	124	8	shake	shake	NOUN
admet-839	124	9	-	-	PUNCT
admet-839	124	10	flask/µdiss	flask/µdiss	NOUN
admet-839	124	11	profiler	profiler	NOUN
admet-839	124	12	™	™	NOUN
admet-839	124	13	spa	spa	NOUN
admet-839	124	14	α	α	NOUN
admet-839	124	15	form	form	NOUN
admet-839	124	16	2.4±0.2	2.4±0.2	NUM
admet-839	124	17	a	a	DET
admet-839	124	18	3.5±0.6	3.5±0.6	NUM
admet-839	124	19	γ	γ	X
admet-839	124	20	form	form	VERB
admet-839	124	21	1.3±0.3	1.3±0.3	NUM
admet-839	124	22	b	b	SYM
admet-839	124	23	1.5±0.2	1.5±0.2	NUM
admet-839	124	24	a	a	DET
admet-839	124	25	reference	reference	NOUN
admet-839	124	26	[	[	X
admet-839	124	27	20	20	NUM
admet-839	124	28	]	]	PUNCT
admet-839	124	29	.	.	PUNCT
admet-839	125	1	b	b	X
admet-839	125	2	reference	reference	NOUN
admet-839	125	3	[	[	X
admet-839	125	4	18	18	NUM
admet-839	125	5	]	]	PUNCT
admet-839	125	6	http://dx.doi.org/10.5599/admet.839	http://dx.doi.org/10.5599/admet.839	PROPN
admet-839	125	7	jernej	jernej	PROPN
admet-839	125	8	štukelj	štukelj	PROPN
admet-839	125	9	et	et	PROPN
admet-839	125	10	al	al	PROPN
admet-839	125	11	.	.	PROPN
admet-839	125	12	admet	admet	PROPN
admet-839	125	13	&	&	CCONJ
admet-839	125	14	dmpk	dmpk	PROPN
admet-839	125	15	8(4	8(4	NOUN
admet-839	125	16	)	)	PUNCT
admet-839	125	17	(	(	PUNCT
admet-839	125	18	2020	2020	NUM
admet-839	125	19	)	)	PUNCT
admet-839	125	20	401	401	NUM
admet-839	125	21	-	-	SYM
admet-839	125	22	409	409	NUM
admet-839	125	23	406	406	NUM
admet-839	125	24	tracking	track	VERB
admet-839	125	25	the	the	DET
admet-839	125	26	solid	solid	ADJ
admet-839	125	27	-	-	PUNCT
admet-839	125	28	state	state	NOUN
admet-839	125	29	changes	change	NOUN
admet-839	125	30	and	and	CCONJ
admet-839	125	31	amorphous	amorphous	ADJ
admet-839	125	32	solubility	solubility	NOUN
admet-839	125	33	over	over	ADP
admet-839	125	34	time	time	NOUN
admet-839	125	35	the	the	DET
admet-839	125	36	xrpd	xrpd	PROPN
admet-839	125	37	diffractograms	diffractogram	NOUN
admet-839	125	38	recorded	record	VERB
admet-839	125	39	over	over	ADP
admet-839	125	40	time	time	NOUN
admet-839	125	41	of	of	ADP
admet-839	125	42	the	the	DET
admet-839	125	43	two	two	NUM
admet-839	125	44	amorphous	amorphous	ADJ
admet-839	125	45	samples	sample	NOUN
admet-839	125	46	stored	store	VERB
admet-839	125	47	at	at	ADP
admet-839	125	48	22	22	NUM
admet-839	125	49	°	°	NUM
admet-839	125	50	c/23	c/23	ADJ
admet-839	125	51	%	%	NOUN
admet-839	125	52	rh	rh	NOUN
admet-839	125	53	and	and	CCONJ
admet-839	125	54	22	22	NUM
admet-839	125	55	°	°	NUM
admet-839	125	56	c/75	c/75	NOUN
admet-839	125	57	%	%	NOUN
admet-839	125	58	rh	rh	PROPN
admet-839	125	59	are	be	AUX
admet-839	125	60	presented	present	VERB
admet-839	125	61	in	in	ADP
admet-839	125	62	figure	figure	NOUN
admet-839	125	63	3	3	NUM
admet-839	125	64	.	.	PUNCT
admet-839	125	65	crystallization	crystallization	NOUN
admet-839	125	66	started	start	VERB
admet-839	125	67	sooner	soon	ADV
admet-839	125	68	at	at	ADP
admet-839	125	69	75	75	NUM
admet-839	125	70	%	%	NOUN
admet-839	125	71	rh	rh	NOUN
admet-839	125	72	than	than	ADP
admet-839	125	73	at	at	ADP
admet-839	125	74	23	23	NUM
admet-839	125	75	%	%	NOUN
admet-839	125	76	rh	rh	NOUN
admet-839	125	77	,	,	PUNCT
admet-839	125	78	as	as	SCONJ
admet-839	125	79	peaks	peak	NOUN
admet-839	125	80	of	of	ADP
admet-839	125	81	crystallinity	crystallinity	NOUN
admet-839	125	82	can	can	AUX
admet-839	125	83	already	already	ADV
admet-839	125	84	be	be	AUX
admet-839	125	85	seen	see	VERB
admet-839	125	86	on	on	ADP
admet-839	125	87	the	the	DET
admet-839	125	88	second	second	ADJ
admet-839	125	89	day	day	NOUN
admet-839	125	90	(	(	PUNCT
admet-839	125	91	figure	figure	NOUN
admet-839	125	92	3b	3b	NUM
admet-839	125	93	)	)	PUNCT
admet-839	125	94	.	.	PUNCT
admet-839	126	1	in	in	ADP
admet-839	126	2	contrast	contrast	NOUN
admet-839	126	3	,	,	PUNCT
admet-839	126	4	at	at	ADP
admet-839	126	5	23	23	NUM
admet-839	126	6	%	%	NOUN
admet-839	126	7	rh	rh	NOUN
admet-839	126	8	the	the	DET
admet-839	126	9	first	first	ADJ
admet-839	126	10	peaks	peak	NOUN
admet-839	126	11	of	of	ADP
admet-839	126	12	crystallinity	crystallinity	NOUN
admet-839	126	13	can	can	AUX
admet-839	126	14	be	be	AUX
admet-839	126	15	only	only	ADV
admet-839	126	16	observed	observe	VERB
admet-839	126	17	at	at	ADP
admet-839	126	18	day	day	NOUN
admet-839	126	19	7	7	NUM
admet-839	126	20	(	(	PUNCT
admet-839	126	21	figure	figure	NOUN
admet-839	126	22	3a	3a	NUM
admet-839	126	23	)	)	PUNCT
admet-839	126	24	.	.	PUNCT
admet-839	127	1	both	both	DET
admet-839	127	2	samples	sample	NOUN
admet-839	127	3	predominantly	predominantly	ADV
admet-839	127	4	crystallized	crystallize	VERB
admet-839	127	5	into	into	ADP
admet-839	127	6	the	the	DET
admet-839	127	7	γ	γ	PROPN
admet-839	127	8	form	form	NOUN
admet-839	127	9	;	;	PUNCT
admet-839	127	10	the	the	DET
admet-839	127	11	differences	difference	NOUN
admet-839	127	12	in	in	ADP
admet-839	127	13	relative	relative	ADJ
admet-839	127	14	peak	peak	NOUN
admet-839	127	15	intensities	intensity	NOUN
admet-839	127	16	for	for	ADP
admet-839	127	17	the	the	DET
admet-839	127	18	stored	store	VERB
admet-839	127	19	samples	sample	NOUN
admet-839	127	20	versus	versus	ADP
admet-839	127	21	the	the	DET
admet-839	127	22	reference	reference	NOUN
admet-839	127	23	γ	γ	PROPN
admet-839	127	24	form	form	NOUN
admet-839	127	25	diffractogram	diffractogram	NOUN
admet-839	127	26	most	most	ADV
admet-839	127	27	likely	likely	ADV
admet-839	127	28	arise	arise	VERB
admet-839	127	29	due	due	ADP
admet-839	127	30	to	to	ADP
admet-839	127	31	crystal	crystal	NOUN
admet-839	127	32	habit	habit	NOUN
admet-839	127	33	(	(	PUNCT
admet-839	127	34	or	or	CCONJ
admet-839	127	35	possibly	possibly	ADV
admet-839	127	36	preferred	preferred	ADJ
admet-839	127	37	crystal	crystal	NOUN
admet-839	127	38	orientation	orientation	NOUN
admet-839	127	39	)	)	PUNCT
admet-839	127	40	differences	difference	NOUN
admet-839	127	41	associated	associate	VERB
admet-839	127	42	with	with	ADP
admet-839	127	43	the	the	DET
admet-839	127	44	different	different	ADJ
admet-839	127	45	crystal	crystal	NOUN
admet-839	127	46	growth	growth	NOUN
admet-839	127	47	conditions	condition	NOUN
admet-839	127	48	.	.	PUNCT
admet-839	128	1	the	the	DET
admet-839	128	2	presence	presence	NOUN
admet-839	128	3	of	of	ADP
admet-839	128	4	a	a	DET
admet-839	128	5	minor	minor	ADJ
admet-839	128	6	amount	amount	NOUN
admet-839	128	7	of	of	ADP
admet-839	128	8	the	the	DET
admet-839	128	9	α	α	PROPN
admet-839	128	10	form	form	NOUN
admet-839	128	11	is	be	AUX
admet-839	128	12	indicated	indicate	VERB
admet-839	128	13	by	by	ADP
admet-839	128	14	a	a	DET
admet-839	128	15	small	small	ADJ
admet-839	128	16	peak	peak	NOUN
admet-839	128	17	appearing	appear	VERB
admet-839	128	18	at	at	ADP
admet-839	128	19	8.5	8.5	NUM
admet-839	128	20	°	°	NOUN
admet-839	128	21	.	.	PUNCT
admet-839	129	1	a	a	DET
admet-839	129	2	study	study	NOUN
admet-839	129	3	with	with	ADP
admet-839	129	4	amorphous	amorphous	ADJ
admet-839	129	5	indomethacin	indomethacin	NOUN
admet-839	129	6	tablets	tablet	NOUN
admet-839	129	7	prepared	prepare	VERB
admet-839	129	8	via	via	ADP
admet-839	129	9	the	the	DET
admet-839	129	10	melt	melt	NOUN
admet-839	129	11	and	and	CCONJ
admet-839	129	12	stored	store	VERB
admet-839	129	13	at	at	ADP
admet-839	129	14	30	30	NUM
admet-839	129	15	°	°	NUM
admet-839	129	16	c/23	c/23	ADJ
admet-839	129	17	%	%	NOUN
admet-839	129	18	rh	rh	NOUN
admet-839	129	19	and	and	CCONJ
admet-839	129	20	30	30	NUM
admet-839	129	21	°	°	NUM
admet-839	129	22	c/75	c/75	NOUN
admet-839	129	23	%	%	INTJ
admet-839	129	24	rh	rh	PROPN
admet-839	129	25	was	be	AUX
admet-839	129	26	performed	perform	VERB
admet-839	129	27	by	by	ADP
admet-839	129	28	novakovic	novakovic	PROPN
admet-839	129	29	et	et	PROPN
admet-839	129	30	al	al	PROPN
admet-839	129	31	.	.	PUNCT
admet-839	130	1	[	[	X
admet-839	130	2	26	26	NUM
admet-839	130	3	]	]	PUNCT
admet-839	130	4	.	.	PUNCT
admet-839	131	1	the	the	DET
admet-839	131	2	researchers	researcher	NOUN
admet-839	131	3	stored	store	VERB
admet-839	131	4	tablets	tablet	NOUN
admet-839	131	5	for	for	ADP
admet-839	131	6	22	22	NUM
admet-839	131	7	days	day	NOUN
admet-839	131	8	and	and	CCONJ
admet-839	131	9	observed	observe	VERB
admet-839	131	10	transformation	transformation	NOUN
admet-839	131	11	into	into	ADP
admet-839	131	12	the	the	DET
admet-839	131	13	γ	γ	PROPN
admet-839	131	14	form	form	NOUN
admet-839	131	15	at	at	ADP
admet-839	131	16	23	23	NUM
admet-839	131	17	%	%	NOUN
admet-839	131	18	rh	rh	NOUN
admet-839	131	19	and	and	CCONJ
admet-839	131	20	the	the	DET
admet-839	131	21	α	α	PROPN
admet-839	131	22	form	form	NOUN
admet-839	131	23	at	at	ADP
admet-839	131	24	75	75	NUM
admet-839	131	25	%	%	NOUN
admet-839	131	26	rh	rh	PROPN
admet-839	131	27	.	.	PUNCT
admet-839	132	1	the	the	DET
admet-839	132	2	transformation	transformation	NOUN
admet-839	132	3	,	,	PUNCT
admet-839	132	4	however	however	ADV
admet-839	132	5	,	,	PUNCT
admet-839	132	6	was	be	AUX
admet-839	132	7	not	not	PART
admet-839	132	8	exclusive	exclusive	ADJ
admet-839	132	9	,	,	PUNCT
admet-839	132	10	as	as	SCONJ
admet-839	132	11	regions	region	NOUN
admet-839	132	12	that	that	PRON
admet-839	132	13	could	could	AUX
admet-839	132	14	be	be	AUX
admet-839	132	15	associated	associate	VERB
admet-839	132	16	with	with	ADP
admet-839	132	17	the	the	DET
admet-839	132	18	α	α	PROPN
admet-839	132	19	form	form	NOUN
admet-839	132	20	were	be	AUX
admet-839	132	21	also	also	ADV
admet-839	132	22	detected	detect	VERB
admet-839	132	23	at	at	ADP
admet-839	132	24	23	23	NUM
admet-839	132	25	%	%	NOUN
admet-839	132	26	rh	rh	PROPN
admet-839	132	27	.	.	PUNCT
admet-839	133	1	in	in	ADP
admet-839	133	2	contrast	contrast	NOUN
admet-839	133	3	,	,	PUNCT
admet-839	133	4	patterson	patterson	PROPN
admet-839	133	5	et	et	PROPN
admet-839	133	6	al	al	PROPN
admet-839	133	7	.	.	PROPN
admet-839	133	8	obtained	obtain	VERB
admet-839	133	9	a	a	DET
admet-839	133	10	predominantly	predominantly	ADV
admet-839	133	11	γ	γ	NOUN
admet-839	133	12	sample	sample	NOUN
admet-839	133	13	with	with	ADP
admet-839	133	14	some	some	DET
admet-839	133	15	α	α	NOUN
admet-839	133	16	form	form	NOUN
admet-839	133	17	present	present	ADJ
admet-839	133	18	when	when	SCONJ
admet-839	133	19	they	they	PRON
admet-839	133	20	stored	store	VERB
admet-839	133	21	quench	quench	NOUN
admet-839	133	22	cooled	cool	VERB
admet-839	133	23	amorphous	amorphous	ADJ
admet-839	133	24	indomethacin	indomethacin	NOUN
admet-839	133	25	at	at	ADP
admet-839	133	26	30	30	NUM
admet-839	133	27	°	°	NUM
admet-839	133	28	c/75	c/75	NOUN
admet-839	133	29	%	%	NOUN
admet-839	133	30	rh	rh	PROPN
admet-839	134	1	[	[	X
admet-839	134	2	21	21	NUM
admet-839	134	3	]	]	PUNCT
admet-839	134	4	.	.	PUNCT
admet-839	135	1	this	this	DET
admet-839	135	2	ostensibly	ostensibly	ADV
admet-839	135	3	stochastic	stochastic	ADJ
admet-839	135	4	event	event	NOUN
admet-839	135	5	could	could	AUX
admet-839	135	6	have	have	AUX
admet-839	135	7	been	be	AUX
admet-839	135	8	the	the	DET
admet-839	135	9	result	result	NOUN
admet-839	135	10	of	of	ADP
admet-839	135	11	other	other	ADJ
admet-839	135	12	factors	factor	NOUN
admet-839	135	13	.	.	PUNCT
admet-839	136	1	besides	besides	SCONJ
admet-839	136	2	temperature	temperature	NOUN
admet-839	136	3	and	and	CCONJ
admet-839	136	4	humidity	humidity	NOUN
admet-839	136	5	,	,	PUNCT
admet-839	136	6	preparation	preparation	NOUN
admet-839	136	7	method	method	NOUN
admet-839	136	8	and	and	CCONJ
admet-839	136	9	parameters	parameter	NOUN
admet-839	136	10	can	can	AUX
admet-839	136	11	also	also	ADV
admet-839	136	12	influence	influence	VERB
admet-839	136	13	the	the	DET
admet-839	136	14	resulting	result	VERB
admet-839	136	15	polymorphic	polymorphic	ADJ
admet-839	136	16	form	form	NOUN
admet-839	136	17	[	[	X
admet-839	136	18	24	24	NUM
admet-839	136	19	]	]	PUNCT
admet-839	136	20	.	.	PUNCT
admet-839	137	1	figure	figure	NOUN
admet-839	137	2	3	3	NUM
admet-839	137	3	.	.	PUNCT
admet-839	137	4	xrpd	xrpd	PROPN
admet-839	137	5	diffractograms	diffractogram	NOUN
admet-839	137	6	of	of	ADP
admet-839	137	7	the	the	DET
admet-839	137	8	amorphous	amorphous	ADJ
admet-839	137	9	samples	sample	NOUN
admet-839	137	10	stored	store	VERB
admet-839	137	11	at	at	ADP
admet-839	137	12	(	(	PUNCT
admet-839	137	13	a	a	X
admet-839	137	14	)	)	PUNCT
admet-839	137	15	22	22	NUM
admet-839	137	16	°	°	NUM
admet-839	137	17	c/23	c/23	ADJ
admet-839	137	18	%	%	NOUN
admet-839	138	1	rh	rh	PROPN
admet-839	138	2	and	and	CCONJ
admet-839	138	3	(	(	PUNCT
admet-839	138	4	b	b	NOUN
admet-839	138	5	)	)	PUNCT
admet-839	138	6	22	22	NUM
admet-839	138	7	°	°	NUM
admet-839	138	8	c/75	c/75	PROPN
admet-839	138	9	%	%	INTJ
admet-839	138	10	rh	rh	PROPN
admet-839	138	11	.	.	PROPN
admet-839	138	12	dashed	dash	VERB
admet-839	138	13	lines	line	NOUN
admet-839	138	14	indicate	indicate	VERB
admet-839	138	15	the	the	DET
admet-839	138	16	γ	γ	PROPN
admet-839	138	17	form	form	NOUN
admet-839	138	18	xrpd	xrpd	PROPN
admet-839	138	19	peaks	peak	NOUN
admet-839	138	20	used	use	VERB
admet-839	138	21	for	for	ADP
admet-839	138	22	quantification	quantification	NOUN
admet-839	138	23	:	:	PUNCT
admet-839	138	24	11.6	11.6	NUM
admet-839	138	25	°	°	NOUN
admet-839	138	26	,	,	PUNCT
admet-839	138	27	16.7	16.7	NUM
admet-839	138	28	°	°	NOUN
admet-839	138	29	,	,	PUNCT
admet-839	138	30	21.8	21.8	NUM
admet-839	138	31	°	°	NOUN
admet-839	138	32	and	and	CCONJ
admet-839	138	33	26.6	26.6	NUM
admet-839	138	34	°	°	NOUN
admet-839	138	35	.	.	PUNCT
admet-839	139	1	experimentally	experimentally	ADV
admet-839	139	2	recorded	record	VERB
admet-839	139	3	diffractograms	diffractogram	NOUN
admet-839	139	4	of	of	ADP
admet-839	139	5	α	α	PROPN
admet-839	139	6	and	and	CCONJ
admet-839	139	7	γ	γ	PROPN
admet-839	139	8	indomethacin	indomethacin	NOUN
admet-839	139	9	are	be	AUX
admet-839	139	10	plotted	plot	VERB
admet-839	139	11	for	for	ADP
admet-839	139	12	comparison	comparison	NOUN
admet-839	139	13	.	.	PUNCT
admet-839	140	1	to	to	PART
admet-839	140	2	quantify	quantify	VERB
admet-839	140	3	the	the	DET
admet-839	140	4	solid	solid	ADJ
admet-839	140	5	-	-	PUNCT
admet-839	140	6	state	state	NOUN
admet-839	140	7	changes	change	NOUN
admet-839	140	8	of	of	ADP
admet-839	140	9	the	the	DET
admet-839	140	10	amorphous	amorphous	ADJ
admet-839	140	11	samples	sample	NOUN
admet-839	140	12	,	,	PUNCT
admet-839	140	13	four	four	NUM
admet-839	140	14	distinctive	distinctive	ADJ
admet-839	140	15	peaks	peak	NOUN
admet-839	140	16	characteristic	characteristic	ADJ
admet-839	140	17	of	of	ADP
admet-839	140	18	the	the	DET
admet-839	140	19	γ	γ	PROPN
admet-839	140	20	form	form	NOUN
admet-839	140	21	at	at	ADP
admet-839	140	22	11.6	11.6	NUM
admet-839	140	23	°	°	NOUN
admet-839	140	24	,	,	PUNCT
admet-839	140	25	16.7	16.7	NUM
admet-839	140	26	°	°	NOUN
admet-839	140	27	,	,	PUNCT
admet-839	140	28	21.8	21.8	NUM
admet-839	140	29	°	°	NOUN
admet-839	140	30	and	and	CCONJ
admet-839	140	31	26.6	26.6	NUM
admet-839	140	32	°	°	NOUN
admet-839	140	33	2θ	2θ	NUM
admet-839	140	34	were	be	AUX
admet-839	140	35	selected	select	VERB
admet-839	140	36	and	and	CCONJ
admet-839	140	37	are	be	AUX
admet-839	140	38	indicated	indicate	VERB
admet-839	140	39	by	by	ADP
admet-839	140	40	the	the	DET
admet-839	140	41	dashed	dash	VERB
admet-839	140	42	lines	line	NOUN
admet-839	140	43	in	in	ADP
admet-839	140	44	figure	figure	NOUN
admet-839	140	45	3	3	NUM
admet-839	140	46	.	.	PUNCT
admet-839	141	1	the	the	DET
admet-839	141	2	resulting	result	VERB
admet-839	141	3	values	value	NOUN
admet-839	141	4	were	be	AUX
admet-839	141	5	averaged	average	VERB
admet-839	141	6	and	and	CCONJ
admet-839	141	7	the	the	DET
admet-839	141	8	log	log	NOUN
admet-839	141	9	value	value	NOUN
admet-839	141	10	of	of	ADP
admet-839	141	11	the	the	DET
admet-839	141	12	average	average	NOUN
admet-839	141	13	plotted	plot	VERB
admet-839	141	14	against	against	ADP
admet-839	141	15	time	time	NOUN
admet-839	141	16	(	(	PUNCT
admet-839	141	17	figure	figure	NOUN
admet-839	141	18	4	4	NUM
admet-839	141	19	)	)	PUNCT
admet-839	141	20	.	.	PUNCT
admet-839	142	1	in	in	ADP
admet-839	142	2	80	80	NUM
admet-839	142	3	days	day	NOUN
admet-839	142	4	,	,	PUNCT
admet-839	142	5	the	the	DET
admet-839	142	6	amorphous	amorphous	ADJ
admet-839	142	7	sample	sample	NOUN
admet-839	142	8	stored	store	VERB
admet-839	142	9	at	at	ADP
admet-839	142	10	23	23	NUM
admet-839	142	11	%	%	NOUN
admet-839	142	12	rh	rh	PROPN
admet-839	142	13	almost	almost	ADV
admet-839	142	14	fully	fully	ADV
admet-839	142	15	converted	convert	VERB
admet-839	142	16	into	into	ADP
admet-839	142	17	the	the	DET
admet-839	142	18	γ	γ	PROPN
admet-839	142	19	form	form	NOUN
admet-839	142	20	(	(	PUNCT
admet-839	142	21	figure	figure	NOUN
admet-839	142	22	4a	4a	NUM
admet-839	142	23	)	)	PUNCT
admet-839	142	24	.	.	PUNCT
admet-839	143	1	in	in	ADP
admet-839	143	2	contrast	contrast	NOUN
admet-839	143	3	,	,	PUNCT
admet-839	143	4	full	full	ADJ
admet-839	143	5	conversion	conversion	NOUN
admet-839	143	6	of	of	ADP
admet-839	143	7	the	the	DET
admet-839	143	8	sample	sample	NOUN
admet-839	143	9	stored	store	VERB
admet-839	143	10	at	at	ADP
admet-839	143	11	75	75	NUM
admet-839	143	12	%	%	NOUN
admet-839	143	13	rh	rh	NOUN
admet-839	143	14	,	,	PUNCT
admet-839	143	15	as	as	SCONJ
admet-839	143	16	measured	measure	VERB
admet-839	143	17	by	by	ADP
admet-839	143	18	the	the	DET
admet-839	143	19	averaged	average	VERB
admet-839	143	20	peak	peak	NOUN
admet-839	143	21	intensity	intensity	NOUN
admet-839	143	22	,	,	PUNCT
admet-839	143	23	did	do	AUX
admet-839	143	24	not	not	PART
admet-839	143	25	occur	occur	VERB
admet-839	143	26	despite	despite	SCONJ
admet-839	143	27	the	the	DET
admet-839	143	28	crystallization	crystallization	NOUN
admet-839	143	29	starting	start	VERB
admet-839	143	30	sooner	soon	ADV
admet-839	143	31	than	than	ADP
admet-839	143	32	for	for	ADP
admet-839	143	33	the	the	DET
admet-839	143	34	sample	sample	NOUN
admet-839	143	35	stored	store	VERB
admet-839	143	36	at	at	ADP
admet-839	143	37	23	23	NUM
admet-839	143	38	%	%	NOUN
admet-839	143	39	rh	rh	PROPN
admet-839	143	40	.	.	PUNCT
admet-839	144	1	the	the	DET
admet-839	144	2	presence	presence	NOUN
admet-839	144	3	of	of	ADP
admet-839	144	4	the	the	DET
admet-839	144	5	elevated	elevated	ADJ
admet-839	144	6	xrpd	xrpd	PROPN
admet-839	144	7	baseline	baseline	NOUN
admet-839	144	8	,	,	PUNCT
admet-839	144	9	indicating	indicate	VERB
admet-839	144	10	amorphousness	amorphousness	NOUN
admet-839	144	11	,	,	PUNCT
admet-839	144	12	at	at	ADP
admet-839	144	13	the	the	DET
admet-839	144	14	end	end	NOUN
admet-839	144	15	of	of	ADP
admet-839	144	16	the	the	DET
admet-839	144	17	study	study	NOUN
admet-839	144	18	(	(	PUNCT
admet-839	144	19	figure	figure	NOUN
admet-839	144	20	3b	3b	NUM
admet-839	144	21	)	)	PUNCT
admet-839	144	22	could	could	AUX
admet-839	144	23	be	be	AUX
admet-839	144	24	explained	explain	VERB
admet-839	144	25	by	by	ADP
admet-839	144	26	one	one	NUM
admet-839	144	27	,	,	PUNCT
admet-839	144	28	or	or	CCONJ
admet-839	144	29	a	a	DET
admet-839	144	30	combination	combination	NOUN
admet-839	144	31	,	,	PUNCT
admet-839	144	32	of	of	ADP
admet-839	144	33	two	two	NUM
admet-839	144	34	possibilities	possibility	NOUN
admet-839	144	35	:	:	PUNCT
admet-839	144	36	i	i	NOUN
admet-839	144	37	)	)	PUNCT
admet-839	144	38	rapid	rapid	ADJ
admet-839	144	39	nucleation	nucleation	NOUN
admet-839	144	40	at	at	ADP
admet-839	144	41	higher	high	ADJ
admet-839	144	42	humidity	humidity	NOUN
admet-839	144	43	resulted	result	VERB
admet-839	144	44	in	in	ADP
admet-839	144	45	the	the	DET
admet-839	144	46	formation	formation	NOUN
admet-839	144	47	of	of	ADP
admet-839	144	48	nanocrystals	nanocrystal	NOUN
admet-839	144	49	,	,	PUNCT
admet-839	144	50	which	which	PRON
admet-839	144	51	due	due	ADP
admet-839	144	52	to	to	ADP
admet-839	144	53	their	their	PRON
admet-839	144	54	small	small	ADJ
admet-839	144	55	size	size	NOUN
admet-839	144	56	and	and	CCONJ
admet-839	144	57	many	many	ADJ
admet-839	144	58	defects	defect	NOUN
admet-839	144	59	still	still	ADV
admet-839	144	60	appeared	appear	VERB
admet-839	144	61	partially	partially	ADV
admet-839	144	62	amorphous	amorphous	ADJ
admet-839	144	63	,	,	PUNCT
admet-839	144	64	and	and	CCONJ
admet-839	144	65	ii	ii	X
admet-839	144	66	)	)	PUNCT
admet-839	144	67	the	the	DET
admet-839	144	68	presence	presence	NOUN
admet-839	144	69	and	and	CCONJ
admet-839	144	70	morphology	morphology	NOUN
admet-839	144	71	of	of	ADP
admet-839	144	72	crystals	crystal	NOUN
admet-839	144	73	at	at	ADP
admet-839	144	74	the	the	DET
admet-839	144	75	particle	particle	NOUN
admet-839	144	76	surface	surface	NOUN
admet-839	144	77	may	may	AUX
admet-839	144	78	have	have	AUX
admet-839	144	79	acted	act	VERB
admet-839	144	80	as	as	ADP
admet-839	144	81	a	a	DET
admet-839	144	82	mechanical	mechanical	ADJ
admet-839	144	83	barrier	barrier	NOUN
admet-839	144	84	for	for	ADP
admet-839	144	85	further	further	ADJ
admet-839	144	86	crystal	crystal	NOUN
admet-839	144	87	growth	growth	NOUN
admet-839	144	88	in	in	ADP
admet-839	144	89	the	the	DET
admet-839	144	90	particle	particle	NOUN
admet-839	144	91	core	core	NOUN
admet-839	144	92	.	.	PUNCT
admet-839	145	1	when	when	SCONJ
admet-839	145	2	interpreting	interpret	VERB
admet-839	145	3	the	the	DET
admet-839	145	4	xrpd	xrpd	PROPN
admet-839	145	5	results	result	NOUN
admet-839	145	6	,	,	PUNCT
admet-839	145	7	one	one	PRON
admet-839	145	8	must	must	AUX
admet-839	145	9	also	also	ADV
admet-839	145	10	keep	keep	VERB
admet-839	145	11	in	in	ADP
admet-839	145	12	mind	mind	NOUN
admet-839	145	13	that	that	SCONJ
admet-839	145	14	the	the	DET
admet-839	145	15	penetration	penetration	NOUN
admet-839	145	16	depth	depth	NOUN
admet-839	145	17	of	of	ADP
admet-839	145	18	x	x	NOUN
admet-839	145	19	-	-	NOUN
admet-839	145	20	rays	ray	NOUN
admet-839	145	21	is	be	AUX
admet-839	145	22	in	in	ADP
admet-839	145	23	the	the	DET
admet-839	145	24	order	order	NOUN
admet-839	145	25	of	of	ADP
admet-839	145	26	several	several	ADJ
admet-839	145	27	hundred	hundred	NUM
admet-839	145	28	µm	µm	NOUN
admet-839	145	29	and	and	CCONJ
admet-839	145	30	that	that	SCONJ
admet-839	145	31	results	result	NOUN
admet-839	145	32	may	may	AUX
admet-839	145	33	significantly	significantly	ADV
admet-839	145	34	vary	vary	VERB
admet-839	145	35	if	if	SCONJ
admet-839	145	36	analysed	analyse	VERB
admet-839	145	37	with	with	ADP
admet-839	145	38	a	a	DET
admet-839	145	39	different	different	ADJ
admet-839	145	40	technique	technique	NOUN
admet-839	145	41	[	[	X
admet-839	145	42	13	13	NUM
admet-839	145	43	]	]	PUNCT
admet-839	145	44	.	.	PUNCT
admet-839	146	1	admet	admet	PROPN
admet-839	146	2	&	&	CCONJ
admet-839	146	3	dmpk	dmpk	PROPN
admet-839	146	4	8(4	8(4	NOUN
admet-839	146	5	)	)	PUNCT
admet-839	146	6	(	(	PUNCT
admet-839	146	7	2020	2020	NUM
admet-839	146	8	)	)	PUNCT
admet-839	146	9	401	401	NUM
admet-839	146	10	-	-	SYM
admet-839	146	11	409	409	NUM
admet-839	146	12	amorphous	amorphous	ADJ
admet-839	146	13	solubility	solubility	NOUN
admet-839	146	14	over	over	ADP
admet-839	146	15	time	time	NOUN
admet-839	146	16	doi	doi	PROPN
admet-839	146	17	:	:	PUNCT
admet-839	146	18	https://dx.doi.org/10.5599/admet.839	https://dx.doi.org/10.5599/admet.839	NOUN
admet-839	146	19	407	407	NUM
admet-839	146	20	sampling	sample	VERB
admet-839	146	21	for	for	ADP
admet-839	146	22	the	the	DET
admet-839	146	23	spa	spa	NOUN
admet-839	146	24	measurements	measurement	NOUN
admet-839	146	25	was	be	AUX
admet-839	146	26	conducted	conduct	VERB
admet-839	146	27	as	as	SCONJ
admet-839	146	28	depicted	depict	VERB
admet-839	146	29	in	in	ADP
admet-839	146	30	figure	figure	NOUN
admet-839	146	31	1b	1b	NUM
admet-839	146	32	.	.	PUNCT
admet-839	147	1	three	three	NUM
admet-839	147	2	measurements	measurement	NOUN
admet-839	147	3	of	of	ADP
admet-839	147	4	the	the	DET
admet-839	147	5	amorphous	amorphous	ADJ
admet-839	147	6	solubility	solubility	NOUN
admet-839	147	7	of	of	ADP
admet-839	147	8	each	each	DET
admet-839	147	9	sample	sample	NOUN
admet-839	147	10	conducted	conduct	VERB
admet-839	147	11	on	on	ADP
admet-839	147	12	the	the	DET
admet-839	147	13	same	same	ADJ
admet-839	147	14	day	day	NOUN
admet-839	147	15	were	be	AUX
admet-839	147	16	averaged	average	VERB
admet-839	147	17	and	and	CCONJ
admet-839	147	18	plotted	plot	VERB
admet-839	147	19	against	against	ADP
admet-839	147	20	time	time	NOUN
admet-839	147	21	(	(	PUNCT
admet-839	147	22	figure	figure	NOUN
admet-839	147	23	4	4	NUM
admet-839	147	24	)	)	PUNCT
admet-839	147	25	.	.	PUNCT
admet-839	148	1	for	for	ADP
admet-839	148	2	the	the	DET
admet-839	148	3	sample	sample	NOUN
admet-839	148	4	stored	store	VERB
admet-839	148	5	at	at	ADP
admet-839	148	6	23	23	NUM
admet-839	148	7	%	%	NOUN
admet-839	148	8	rh	rh	PROPN
admet-839	148	9	,	,	PUNCT
admet-839	148	10	the	the	DET
admet-839	148	11	amorphous	amorphous	ADJ
admet-839	148	12	solubility	solubility	NOUN
admet-839	148	13	gradually	gradually	ADV
admet-839	148	14	decreased	decrease	VERB
admet-839	148	15	and	and	CCONJ
admet-839	148	16	reached	reach	VERB
admet-839	148	17	that	that	PRON
admet-839	148	18	of	of	ADP
admet-839	148	19	the	the	DET
admet-839	148	20	γ	γ	PROPN
admet-839	148	21	crystalline	crystalline	NOUN
admet-839	148	22	form	form	NOUN
admet-839	148	23	(	(	PUNCT
admet-839	148	24	1.69	1.69	NUM
admet-839	148	25	±	±	NUM
admet-839	148	26	0.58	0.58	NUM
admet-839	148	27	µg	µg	NOUN
admet-839	148	28	/	/	SYM
admet-839	148	29	ml	ml	NOUN
admet-839	148	30	)	)	PUNCT
admet-839	148	31	at	at	ADP
admet-839	148	32	day	day	NOUN
admet-839	148	33	25	25	NUM
admet-839	148	34	.	.	PUNCT
admet-839	149	1	in	in	ADP
admet-839	149	2	contrast	contrast	NOUN
admet-839	149	3	,	,	PUNCT
admet-839	149	4	the	the	DET
admet-839	149	5	xrpd	xrpd	PROPN
admet-839	149	6	signal	signal	PROPN
admet-839	149	7	reached	reach	VERB
admet-839	149	8	a	a	DET
admet-839	149	9	plateau	plateau	NOUN
admet-839	149	10	only	only	ADV
admet-839	149	11	around	around	ADP
admet-839	149	12	day	day	NOUN
admet-839	149	13	40	40	NUM
admet-839	149	14	(	(	PUNCT
admet-839	149	15	figure	figure	NOUN
admet-839	149	16	4a	4a	NUM
admet-839	149	17	)	)	PUNCT
admet-839	149	18	.	.	PUNCT
admet-839	150	1	thus	thus	ADV
admet-839	150	2	,	,	PUNCT
admet-839	150	3	even	even	ADV
admet-839	150	4	prior	prior	ADV
admet-839	150	5	to	to	ADP
admet-839	150	6	the	the	DET
admet-839	150	7	sample	sample	NOUN
admet-839	150	8	being	be	AUX
admet-839	150	9	fully	fully	ADV
admet-839	150	10	crystalline	crystalline	ADJ
admet-839	150	11	based	base	VERB
admet-839	150	12	on	on	ADP
admet-839	150	13	the	the	DET
admet-839	150	14	xrpd	xrpd	PROPN
admet-839	150	15	measurements	measurement	NOUN
admet-839	150	16	,	,	PUNCT
admet-839	150	17	its	its	PRON
admet-839	150	18	dissolution	dissolution	NOUN
admet-839	150	19	rate	rate	NOUN
admet-839	150	20	and	and	CCONJ
admet-839	150	21	solubility	solubility	NOUN
admet-839	150	22	were	be	AUX
admet-839	150	23	already	already	ADV
admet-839	150	24	fully	fully	ADV
admet-839	150	25	governed	govern	VERB
admet-839	150	26	by	by	ADP
admet-839	150	27	the	the	DET
admet-839	150	28	crystalline	crystalline	NOUN
admet-839	150	29	form	form	NOUN
admet-839	150	30	.	.	PUNCT
admet-839	151	1	this	this	PRON
admet-839	151	2	can	can	AUX
admet-839	151	3	be	be	AUX
admet-839	151	4	explained	explain	VERB
admet-839	151	5	by	by	ADP
admet-839	151	6	the	the	DET
admet-839	151	7	surface	surface	NOUN
admet-839	151	8	crystallizing	crystallize	VERB
admet-839	151	9	faster	fast	ADV
admet-839	151	10	than	than	ADP
admet-839	151	11	the	the	DET
admet-839	151	12	bulk	bulk	NOUN
admet-839	151	13	[	[	X
admet-839	151	14	8	8	NUM
admet-839	151	15	]	]	PUNCT
admet-839	151	16	.	.	PUNCT
admet-839	152	1	priemel	priemel	X
admet-839	152	2	et	et	PROPN
admet-839	152	3	al	al	PROPN
admet-839	152	4	.	.	PROPN
admet-839	152	5	have	have	AUX
admet-839	152	6	observed	observe	VERB
admet-839	152	7	that	that	SCONJ
admet-839	152	8	only	only	ADV
admet-839	152	9	the	the	DET
admet-839	152	10	surface	surface	NOUN
admet-839	152	11	of	of	ADP
admet-839	152	12	freshly	freshly	ADV
admet-839	152	13	prepared	prepare	VERB
admet-839	152	14	amorphous	amorphous	ADJ
admet-839	152	15	tablets	tablet	NOUN
admet-839	152	16	crystallized	crystallize	VERB
admet-839	152	17	during	during	ADP
admet-839	152	18	dissolution	dissolution	ADJ
admet-839	152	19	testing	testing	NOUN
admet-839	153	1	[	[	X
admet-839	153	2	13	13	NUM
admet-839	153	3	]	]	PUNCT
admet-839	153	4	.	.	PUNCT
admet-839	154	1	in	in	ADP
admet-839	154	2	contrast	contrast	NOUN
admet-839	154	3	,	,	PUNCT
admet-839	154	4	the	the	DET
admet-839	154	5	whole	whole	ADJ
admet-839	154	6	tablet	tablet	NOUN
admet-839	154	7	crystallized	crystallize	VERB
admet-839	154	8	during	during	ADP
admet-839	154	9	dissolution	dissolution	NOUN
admet-839	154	10	when	when	SCONJ
admet-839	154	11	it	it	PRON
admet-839	154	12	was	be	AUX
admet-839	154	13	stored	store	VERB
admet-839	154	14	for	for	ADP
admet-839	154	15	5	5	NUM
admet-839	154	16	days	day	NOUN
admet-839	154	17	at	at	ADP
admet-839	154	18	30	30	NUM
admet-839	154	19	°	°	NUM
admet-839	154	20	c/23	c/23	ADJ
admet-839	154	21	%	%	NOUN
admet-839	154	22	rh	rh	PROPN
admet-839	154	23	.	.	PUNCT
admet-839	155	1	the	the	DET
admet-839	155	2	researchers	researcher	NOUN
admet-839	155	3	explained	explain	VERB
admet-839	155	4	the	the	DET
admet-839	155	5	observation	observation	NOUN
admet-839	155	6	by	by	ADP
admet-839	155	7	a	a	DET
admet-839	155	8	denser	dense	ADJ
admet-839	155	9	crystalline	crystalline	NOUN
admet-839	155	10	layer	layer	NOUN
admet-839	155	11	forming	form	VERB
admet-839	155	12	during	during	ADP
admet-839	155	13	dissolution	dissolution	NOUN
admet-839	155	14	,	,	PUNCT
admet-839	155	15	which	which	PRON
admet-839	155	16	acted	act	VERB
admet-839	155	17	as	as	ADP
admet-839	155	18	a	a	DET
admet-839	155	19	mechanical	mechanical	ADJ
admet-839	155	20	barrier	barrier	NOUN
admet-839	155	21	for	for	ADP
admet-839	155	22	further	further	ADJ
admet-839	155	23	solution	solution	NOUN
admet-839	155	24	-	-	PUNCT
admet-839	155	25	mediated	mediate	VERB
admet-839	155	26	crystallization	crystallization	NOUN
admet-839	155	27	,	,	PUNCT
admet-839	155	28	versus	versus	ADP
admet-839	155	29	a	a	DET
admet-839	155	30	less	less	ADV
admet-839	155	31	dense	dense	ADJ
admet-839	155	32	crystalline	crystalline	NOUN
admet-839	155	33	layer	layer	NOUN
admet-839	155	34	forming	form	VERB
admet-839	155	35	during	during	ADP
admet-839	155	36	storage	storage	NOUN
admet-839	155	37	,	,	PUNCT
admet-839	155	38	which	which	PRON
admet-839	155	39	eventually	eventually	ADV
admet-839	155	40	promoted	promote	VERB
admet-839	155	41	the	the	DET
admet-839	155	42	migration	migration	NOUN
admet-839	155	43	of	of	ADP
admet-839	155	44	crystallization	crystallization	NOUN
admet-839	155	45	further	far	ADV
admet-839	155	46	into	into	ADP
admet-839	155	47	the	the	DET
admet-839	155	48	tablet	tablet	NOUN
admet-839	155	49	core	core	NOUN
admet-839	155	50	.	.	PUNCT
admet-839	156	1	consequently	consequently	ADV
admet-839	156	2	,	,	PUNCT
admet-839	156	3	the	the	DET
admet-839	156	4	dissolution	dissolution	ADJ
admet-839	156	5	rate	rate	NOUN
admet-839	156	6	of	of	ADP
admet-839	156	7	amorphous	amorphous	ADJ
admet-839	156	8	indomethacin	indomethacin	NOUN
admet-839	156	9	tablets	tablet	NOUN
admet-839	156	10	stored	store	VERB
admet-839	156	11	for	for	ADP
admet-839	156	12	five	five	NUM
admet-839	156	13	days	day	NOUN
admet-839	156	14	matched	match	VERB
admet-839	156	15	the	the	DET
admet-839	156	16	dissolution	dissolution	NOUN
admet-839	156	17	rate	rate	NOUN
admet-839	156	18	of	of	ADP
admet-839	156	19	the	the	DET
admet-839	156	20	γ	γ	PROPN
admet-839	156	21	form	form	NOUN
admet-839	156	22	.	.	PUNCT
admet-839	157	1	figure	figure	NOUN
admet-839	157	2	4	4	NUM
admet-839	157	3	.	.	PUNCT
admet-839	158	1	(	(	PUNCT
admet-839	158	2	a	a	X
admet-839	158	3	)	)	PUNCT
admet-839	158	4	plot	plot	NOUN
admet-839	158	5	of	of	ADP
admet-839	158	6	the	the	DET
admet-839	158	7	xrpd	xrpd	PROPN
admet-839	158	8	quantified	quantified	PROPN
admet-839	158	9	signal	signal	NOUN
admet-839	158	10	and	and	CCONJ
admet-839	158	11	amorphous	amorphous	ADJ
admet-839	158	12	solubility	solubility	NOUN
admet-839	158	13	of	of	ADP
admet-839	158	14	the	the	DET
admet-839	158	15	sample	sample	NOUN
admet-839	158	16	stored	store	VERB
admet-839	158	17	at	at	ADP
admet-839	158	18	22	22	NUM
admet-839	158	19	°	°	NUM
admet-839	158	20	c/23	c/23	ADJ
admet-839	158	21	%	%	NOUN
admet-839	158	22	rh	rh	PROPN
admet-839	158	23	.	.	PROPN
admet-839	159	1	dotted	dotted	ADJ
admet-839	159	2	line	line	NOUN
admet-839	159	3	represents	represent	VERB
admet-839	159	4	the	the	DET
admet-839	159	5	average	average	ADJ
admet-839	159	6	plateau	plateau	NOUN
admet-839	159	7	solubility	solubility	NOUN
admet-839	159	8	(	(	PUNCT
admet-839	159	9	1.69	1.69	NUM
admet-839	159	10	±	±	NUM
admet-839	159	11	0.58	0.58	NUM
admet-839	159	12	µg	µg	NOUN
admet-839	159	13	/	/	SYM
admet-839	159	14	ml	ml	NOUN
admet-839	159	15	)	)	PUNCT
admet-839	159	16	.	.	PUNCT
admet-839	160	1	(	(	PUNCT
admet-839	160	2	b	b	X
admet-839	160	3	)	)	PUNCT
admet-839	160	4	plot	plot	NOUN
admet-839	160	5	of	of	ADP
admet-839	160	6	the	the	DET
admet-839	160	7	xrpd	xrpd	PROPN
admet-839	160	8	quantified	quantified	PROPN
admet-839	160	9	signal	signal	NOUN
admet-839	160	10	and	and	CCONJ
admet-839	160	11	amorphous	amorphous	ADJ
admet-839	160	12	solubility	solubility	NOUN
admet-839	160	13	of	of	ADP
admet-839	160	14	the	the	DET
admet-839	160	15	sample	sample	NOUN
admet-839	160	16	stored	store	VERB
admet-839	160	17	at	at	ADP
admet-839	160	18	22	22	NUM
admet-839	160	19	°	°	NUM
admet-839	160	20	c/75	c/75	PROPN
admet-839	160	21	%	%	INTJ
admet-839	160	22	rh	rh	PROPN
admet-839	160	23	.	.	PROPN
admet-839	161	1	dotted	dotted	ADJ
admet-839	161	2	line	line	NOUN
admet-839	161	3	represents	represent	VERB
admet-839	161	4	the	the	DET
admet-839	161	5	average	average	ADJ
admet-839	161	6	plateau	plateau	NOUN
admet-839	161	7	solubility	solubility	NOUN
admet-839	161	8	(	(	PUNCT
admet-839	161	9	2.04	2.04	NUM
admet-839	161	10	±	±	NUM
admet-839	161	11	0.79	0.79	NUM
admet-839	161	12	µg	µg	NOUN
admet-839	161	13	/	/	SYM
admet-839	161	14	ml	ml	NOUN
admet-839	161	15	)	)	PUNCT
admet-839	161	16	.	.	PUNCT
admet-839	162	1	for	for	ADP
admet-839	162	2	the	the	DET
admet-839	162	3	sample	sample	NOUN
admet-839	162	4	stored	store	VERB
admet-839	162	5	at	at	ADP
admet-839	162	6	75	75	NUM
admet-839	162	7	%	%	NOUN
admet-839	162	8	rh	rh	PROPN
admet-839	162	9	,	,	PUNCT
admet-839	162	10	the	the	DET
admet-839	162	11	solubility	solubility	NOUN
admet-839	162	12	sharply	sharply	ADV
admet-839	162	13	drops	drop	VERB
admet-839	162	14	already	already	ADV
admet-839	162	15	on	on	ADP
admet-839	162	16	the	the	DET
admet-839	162	17	second	second	ADJ
admet-839	162	18	day	day	NOUN
admet-839	162	19	and	and	CCONJ
admet-839	162	20	then	then	ADV
admet-839	162	21	fluctuates	fluctuate	VERB
admet-839	162	22	around	around	ADP
admet-839	162	23	2.04	2.04	NUM
admet-839	162	24	µg	µg	NOUN
admet-839	162	25	/	/	SYM
admet-839	162	26	ml	ml	ADV
admet-839	162	27	–	–	PUNCT
admet-839	162	28	slightly	slightly	ADV
admet-839	162	29	above	above	ADP
admet-839	162	30	the	the	DET
admet-839	162	31	solubility	solubility	NOUN
admet-839	162	32	of	of	ADP
admet-839	162	33	the	the	DET
admet-839	162	34	reference	reference	NOUN
admet-839	162	35	γ	γ	NOUN
admet-839	162	36	form	form	NOUN
admet-839	162	37	,	,	PUNCT
admet-839	162	38	but	but	CCONJ
admet-839	162	39	below	below	ADP
admet-839	162	40	the	the	DET
admet-839	162	41	solubility	solubility	NOUN
admet-839	162	42	of	of	ADP
admet-839	162	43	the	the	DET
admet-839	162	44	α	α	PROPN
admet-839	162	45	form	form	NOUN
admet-839	162	46	measured	measure	VERB
admet-839	162	47	in	in	ADP
admet-839	162	48	this	this	DET
admet-839	162	49	study	study	NOUN
admet-839	162	50	(	(	PUNCT
admet-839	162	51	3.5	3.5	NUM
admet-839	162	52	±	±	NUM
admet-839	162	53	0.6	0.6	NUM
admet-839	162	54	µg	µg	NOUN
admet-839	162	55	/	/	SYM
admet-839	162	56	ml	ml	NOUN
admet-839	162	57	)	)	PUNCT
admet-839	162	58	.	.	PUNCT
admet-839	163	1	we	we	PRON
admet-839	163	2	have	have	AUX
admet-839	163	3	earlier	early	ADV
admet-839	163	4	reported	report	VERB
admet-839	163	5	the	the	DET
admet-839	163	6	solubility	solubility	NOUN
admet-839	163	7	of	of	ADP
admet-839	163	8	the	the	DET
admet-839	163	9	α	α	PROPN
admet-839	163	10	indomethacin	indomethacin	NOUN
admet-839	163	11	form	form	NOUN
admet-839	163	12	being	be	AUX
admet-839	163	13	roughly	roughly	ADV
admet-839	163	14	3	3	NUM
admet-839	163	15	times	time	NOUN
admet-839	163	16	higher	high	ADJ
admet-839	163	17	compared	compare	VERB
admet-839	163	18	to	to	ADP
admet-839	163	19	the	the	DET
admet-839	163	20	solubility	solubility	NOUN
admet-839	163	21	of	of	ADP
admet-839	163	22	the	the	DET
admet-839	163	23	γ	γ	PROPN
admet-839	163	24	form	form	NOUN
admet-839	163	25	[	[	X
admet-839	163	26	22	22	NUM
admet-839	163	27	]	]	PUNCT
admet-839	163	28	.	.	PUNCT
admet-839	164	1	however	however	ADV
admet-839	164	2	,	,	PUNCT
admet-839	164	3	the	the	DET
admet-839	164	4	higher	high	ADJ
admet-839	164	5	solubility	solubility	NOUN
admet-839	164	6	of	of	ADP
admet-839	164	7	the	the	DET
admet-839	164	8	amorphous	amorphous	ADJ
admet-839	164	9	sample	sample	NOUN
admet-839	164	10	stored	store	VERB
admet-839	164	11	at	at	ADP
admet-839	164	12	75	75	NUM
admet-839	164	13	%	%	NOUN
admet-839	164	14	rh	rh	NOUN
admet-839	164	15	measured	measure	VERB
admet-839	164	16	over	over	ADP
admet-839	164	17	time	time	NOUN
admet-839	164	18	in	in	ADP
admet-839	164	19	this	this	DET
admet-839	164	20	study	study	NOUN
admet-839	164	21	is	be	AUX
admet-839	164	22	most	most	ADV
admet-839	164	23	likely	likely	ADJ
admet-839	164	24	the	the	DET
admet-839	164	25	result	result	NOUN
admet-839	164	26	of	of	ADP
admet-839	164	27	one	one	NUM
admet-839	164	28	or	or	CCONJ
admet-839	164	29	both	both	PRON
admet-839	164	30	of	of	ADP
admet-839	164	31	the	the	DET
admet-839	164	32	following	follow	VERB
admet-839	164	33	phenomena	phenomena	PROPN
admet-839	164	34	:	:	PUNCT
admet-839	164	35	i	i	X
admet-839	164	36	)	)	PUNCT
admet-839	164	37	the	the	DET
admet-839	164	38	presence	presence	NOUN
admet-839	164	39	of	of	ADP
admet-839	164	40	minor	minor	ADJ
admet-839	164	41	amounts	amount	NOUN
admet-839	164	42	of	of	ADP
admet-839	164	43	the	the	DET
admet-839	164	44	α	α	NOUN
admet-839	164	45	form	form	NOUN
admet-839	164	46	in	in	ADP
admet-839	164	47	the	the	DET
admet-839	164	48	sample	sample	NOUN
admet-839	164	49	,	,	PUNCT
admet-839	164	50	and	and	CCONJ
admet-839	164	51	ii	ii	X
admet-839	164	52	)	)	PUNCT
admet-839	164	53	differences	difference	NOUN
admet-839	164	54	in	in	ADP
admet-839	164	55	surface	surface	NOUN
admet-839	164	56	morphology	morphology	NOUN
admet-839	164	57	,	,	PUNCT
admet-839	164	58	including	include	VERB
admet-839	164	59	crystal	crystal	NOUN
admet-839	164	60	habit	habit	NOUN
admet-839	164	61	,	,	PUNCT
admet-839	164	62	size	size	NOUN
admet-839	164	63	and	and	CCONJ
admet-839	164	64	crystal	crystal	NOUN
admet-839	164	65	defects	defect	NOUN
admet-839	164	66	,	,	PUNCT
admet-839	164	67	due	due	ADP
admet-839	164	68	to	to	ADP
admet-839	164	69	nanocrystals	nanocrystal	NOUN
admet-839	164	70	forming	form	VERB
admet-839	164	71	during	during	ADP
admet-839	164	72	storage	storage	NOUN
admet-839	164	73	,	,	PUNCT
admet-839	164	74	as	as	SCONJ
admet-839	164	75	observed	observe	VERB
admet-839	164	76	by	by	ADP
admet-839	164	77	priemel	priemel	X
admet-839	164	78	et	et	PROPN
admet-839	164	79	al	al	PROPN
admet-839	164	80	.	.	PUNCT
admet-839	165	1	[	[	X
admet-839	165	2	13	13	NUM
admet-839	165	3	]	]	PUNCT
admet-839	165	4	,	,	PUNCT
admet-839	165	5	versus	versus	ADP
admet-839	165	6	single	single	ADJ
admet-839	165	7	micro	micro	ADJ
admet-839	165	8	-	-	NOUN
admet-839	165	9	scale	scale	ADJ
admet-839	165	10	crystals	crystal	NOUN
admet-839	165	11	of	of	ADP
admet-839	165	12	the	the	DET
admet-839	165	13	reference	reference	NOUN
admet-839	165	14	γ	γ	NOUN
admet-839	165	15	form	form	NOUN
admet-839	165	16	.	.	PUNCT
admet-839	166	1	the	the	DET
admet-839	166	2	sharp	sharp	ADJ
admet-839	166	3	drop	drop	NOUN
admet-839	166	4	in	in	ADP
admet-839	166	5	solubility	solubility	NOUN
admet-839	166	6	on	on	ADP
admet-839	166	7	the	the	DET
admet-839	166	8	second	second	ADJ
admet-839	166	9	day	day	NOUN
admet-839	166	10	,	,	PUNCT
admet-839	166	11	on	on	ADP
admet-839	166	12	the	the	DET
admet-839	166	13	other	other	ADJ
admet-839	166	14	hand	hand	NOUN
admet-839	166	15	,	,	PUNCT
admet-839	166	16	may	may	AUX
admet-839	166	17	be	be	AUX
admet-839	166	18	the	the	DET
admet-839	166	19	result	result	NOUN
admet-839	166	20	of	of	ADP
admet-839	166	21	two	two	NUM
admet-839	166	22	coinciding	coincide	VERB
admet-839	166	23	factors	factor	NOUN
admet-839	166	24	:	:	PUNCT
admet-839	166	25	i	i	PRON
admet-839	166	26	)	)	PUNCT
admet-839	166	27	grinding	grind	VERB
admet-839	166	28	resulted	result	VERB
admet-839	166	29	in	in	ADP
admet-839	166	30	the	the	DET
admet-839	166	31	formation	formation	NOUN
admet-839	166	32	of	of	ADP
admet-839	166	33	crystallization	crystallization	NOUN
admet-839	166	34	nuclei	nucleus	NOUN
admet-839	166	35	on	on	ADP
admet-839	166	36	the	the	DET
admet-839	166	37	surface	surface	NOUN
admet-839	166	38	of	of	ADP
admet-839	166	39	the	the	DET
admet-839	166	40	particles	particle	NOUN
admet-839	166	41	,	,	PUNCT
admet-839	166	42	which	which	PRON
admet-839	166	43	were	be	AUX
admet-839	166	44	undetectable	undetectable	ADJ
admet-839	166	45	with	with	ADP
admet-839	166	46	the	the	DET
admet-839	166	47	xrpd	xrpd	PROPN
admet-839	167	1	[	[	X
admet-839	167	2	21	21	NUM
admet-839	167	3	]	]	PUNCT
admet-839	167	4	,	,	PUNCT
admet-839	167	5	and	and	CCONJ
admet-839	167	6	ii	ii	X
admet-839	167	7	)	)	PUNCT
admet-839	167	8	during	during	ADP
admet-839	167	9	storage	storage	NOUN
admet-839	167	10	,	,	PUNCT
admet-839	167	11	adsorbed	adsorb	VERB
admet-839	167	12	water	water	NOUN
admet-839	167	13	on	on	ADP
admet-839	167	14	the	the	DET
admet-839	167	15	surface	surface	NOUN
admet-839	167	16	increased	increase	VERB
admet-839	167	17	the	the	DET
admet-839	167	18	molecular	molecular	ADJ
admet-839	167	19	mobility	mobility	NOUN
admet-839	167	20	and	and	CCONJ
admet-839	167	21	decreased	decrease	VERB
admet-839	167	22	the	the	DET
admet-839	167	23	tg	tg	PROPN
admet-839	167	24	of	of	ADP
admet-839	167	25	the	the	DET
admet-839	167	26	amorphous	amorphous	ADJ
admet-839	167	27	indomethacin	indomethacin	NOUN
admet-839	167	28	thus	thus	ADV
admet-839	167	29	further	far	ADV
admet-839	167	30	facilitating	facilitate	VERB
admet-839	167	31	the	the	DET
admet-839	167	32	surface	surface	NOUN
admet-839	167	33	crystallization	crystallization	NOUN
admet-839	167	34	[	[	X
admet-839	167	35	6,10	6,10	X
admet-839	167	36	]	]	PUNCT
admet-839	167	37	.	.	PUNCT
admet-839	168	1	once	once	ADV
admet-839	168	2	exposed	expose	VERB
admet-839	168	3	to	to	ADP
admet-839	168	4	the	the	DET
admet-839	168	5	dissolution	dissolution	NOUN
admet-839	168	6	medium	medium	NOUN
admet-839	168	7	,	,	PUNCT
admet-839	168	8	even	even	ADV
admet-839	168	9	if	if	SCONJ
admet-839	168	10	the	the	DET
admet-839	168	11	surface	surface	NOUN
admet-839	168	12	was	be	AUX
admet-839	168	13	not	not	PART
admet-839	168	14	yet	yet	ADV
admet-839	168	15	fully	fully	ADV
admet-839	168	16	crystalline	crystalline	ADJ
admet-839	168	17	,	,	PUNCT
admet-839	168	18	it	it	PRON
admet-839	168	19	was	be	AUX
admet-839	168	20	certainly	certainly	ADV
admet-839	168	21	very	very	ADV
admet-839	168	22	prone	prone	ADJ
admet-839	168	23	to	to	ADP
admet-839	168	24	rapid	rapid	ADJ
admet-839	168	25	crystallization	crystallization	NOUN
admet-839	168	26	.	.	PUNCT
admet-839	169	1	http://dx.doi.org/10.5599/admet.839	http://dx.doi.org/10.5599/admet.839	PROPN
admet-839	169	2	jernej	jernej	PROPN
admet-839	169	3	štukelj	štukelj	PROPN
admet-839	169	4	et	et	PROPN
admet-839	169	5	al	al	PROPN
admet-839	169	6	.	.	PROPN
admet-839	169	7	admet	admet	PROPN
admet-839	169	8	&	&	CCONJ
admet-839	169	9	dmpk	dmpk	PROPN
admet-839	169	10	8(4	8(4	NOUN
admet-839	169	11	)	)	PUNCT
admet-839	169	12	(	(	PUNCT
admet-839	169	13	2020	2020	NUM
admet-839	169	14	)	)	PUNCT
admet-839	169	15	401	401	NUM
admet-839	169	16	-	-	SYM
admet-839	169	17	409	409	NUM
admet-839	169	18	408	408	NUM
admet-839	169	19	conclusions	conclusion	NOUN
admet-839	169	20	in	in	ADP
admet-839	169	21	this	this	DET
admet-839	169	22	study	study	NOUN
admet-839	169	23	,	,	PUNCT
admet-839	169	24	we	we	PRON
admet-839	169	25	have	have	AUX
admet-839	169	26	demonstrated	demonstrate	VERB
admet-839	169	27	the	the	DET
admet-839	169	28	suitability	suitability	NOUN
admet-839	169	29	of	of	ADP
admet-839	169	30	the	the	DET
admet-839	169	31	spa	spa	NOUN
admet-839	169	32	technology	technology	NOUN
admet-839	169	33	for	for	ADP
admet-839	169	34	tracking	track	VERB
admet-839	169	35	the	the	DET
admet-839	169	36	stability	stability	NOUN
admet-839	169	37	/	/	SYM
admet-839	169	38	solubility	solubility	NOUN
admet-839	169	39	of	of	ADP
admet-839	169	40	an	an	DET
admet-839	169	41	initially	initially	ADV
admet-839	169	42	amorphous	amorphous	ADJ
admet-839	169	43	sample	sample	NOUN
admet-839	169	44	during	during	ADP
admet-839	169	45	storage	storage	NOUN
admet-839	169	46	.	.	PUNCT
admet-839	170	1	the	the	DET
admet-839	170	2	short	short	ADJ
admet-839	170	3	equilibration	equilibration	NOUN
admet-839	170	4	time	time	NOUN
admet-839	170	5	and	and	CCONJ
admet-839	170	6	low	low	ADJ
admet-839	170	7	sample	sample	NOUN
admet-839	170	8	consumption	consumption	NOUN
admet-839	170	9	of	of	ADP
admet-839	170	10	the	the	DET
admet-839	170	11	method	method	NOUN
admet-839	170	12	enabled	enable	VERB
admet-839	170	13	–	–	PUNCT
admet-839	170	14	for	for	ADP
admet-839	170	15	the	the	DET
admet-839	170	16	first	first	ADJ
admet-839	170	17	time	time	NOUN
admet-839	170	18	–	–	PUNCT
admet-839	170	19	continuous	continuous	ADJ
admet-839	170	20	observation	observation	NOUN
admet-839	170	21	of	of	ADP
admet-839	170	22	solubility	solubility	NOUN
admet-839	170	23	of	of	ADP
admet-839	170	24	a	a	DET
admet-839	170	25	particulate	particulate	NOUN
admet-839	170	26	amorphous	amorphous	ADJ
admet-839	170	27	sample	sample	NOUN
admet-839	170	28	as	as	SCONJ
admet-839	170	29	opposed	oppose	VERB
admet-839	170	30	to	to	ADP
admet-839	170	31	tablets	tablet	NOUN
admet-839	170	32	which	which	PRON
admet-839	170	33	have	have	AUX
admet-839	170	34	conventionally	conventionally	ADV
admet-839	170	35	been	be	AUX
admet-839	170	36	required	require	VERB
admet-839	170	37	.	.	PUNCT
admet-839	171	1	the	the	DET
admet-839	171	2	results	result	NOUN
admet-839	171	3	for	for	ADP
admet-839	171	4	the	the	DET
admet-839	171	5	amorphous	amorphous	ADJ
admet-839	171	6	indomethacin	indomethacin	NOUN
admet-839	171	7	stored	store	VERB
admet-839	171	8	at	at	ADP
admet-839	171	9	22	22	NUM
admet-839	171	10	°	°	NUM
admet-839	171	11	c/23	c/23	ADJ
admet-839	171	12	%	%	NOUN
admet-839	171	13	rh	rh	PROPN
admet-839	171	14	indicate	indicate	VERB
admet-839	171	15	a	a	DET
admet-839	171	16	gradual	gradual	ADJ
admet-839	171	17	decrease	decrease	NOUN
admet-839	171	18	in	in	ADP
admet-839	171	19	solubility	solubility	NOUN
admet-839	171	20	towards	towards	ADP
admet-839	171	21	the	the	DET
admet-839	171	22	intrinsic	intrinsic	ADJ
admet-839	171	23	solubility	solubility	NOUN
admet-839	171	24	of	of	ADP
admet-839	171	25	the	the	DET
admet-839	171	26	γ	γ	PROPN
admet-839	171	27	form	form	NOUN
admet-839	171	28	.	.	PUNCT
admet-839	172	1	the	the	DET
admet-839	172	2	y	y	PROPN
admet-839	172	3	form	form	NOUN
admet-839	172	4	solubility	solubility	NOUN
admet-839	172	5	was	be	AUX
admet-839	172	6	reached	reach	VERB
admet-839	172	7	at	at	ADP
admet-839	172	8	day	day	NOUN
admet-839	172	9	25	25	NUM
admet-839	172	10	,	,	PUNCT
admet-839	172	11	which	which	PRON
admet-839	172	12	was	be	AUX
admet-839	172	13	roughly	roughly	ADV
admet-839	172	14	15	15	NUM
admet-839	172	15	days	day	NOUN
admet-839	172	16	prior	prior	ADV
admet-839	172	17	to	to	ADP
admet-839	172	18	xrpd	xrpd	PROPN
admet-839	172	19	detecting	detect	VERB
admet-839	172	20	a	a	DET
admet-839	172	21	fully	fully	ADV
admet-839	172	22	crystalline	crystalline	ADJ
admet-839	172	23	sample	sample	NOUN
admet-839	172	24	.	.	PUNCT
admet-839	173	1	for	for	ADP
admet-839	173	2	the	the	DET
admet-839	173	3	sample	sample	NOUN
admet-839	173	4	stored	store	VERB
admet-839	173	5	at	at	ADP
admet-839	173	6	22	22	NUM
admet-839	173	7	°	°	NUM
admet-839	173	8	c/75	c/75	PROPN
admet-839	173	9	%	%	NOUN
admet-839	173	10	rh	rh	PROPN
admet-839	173	11	,	,	PUNCT
admet-839	173	12	the	the	DET
admet-839	173	13	xrpd	xrpd	PROPN
admet-839	173	14	signal	signal	PROPN
admet-839	173	15	initially	initially	ADV
admet-839	173	16	indicated	indicate	VERB
admet-839	173	17	fast	fast	ADJ
admet-839	173	18	crystallization	crystallization	NOUN
admet-839	173	19	.	.	PUNCT
admet-839	174	1	however	however	ADV
admet-839	174	2	,	,	PUNCT
admet-839	174	3	the	the	DET
admet-839	174	4	sample	sample	NOUN
admet-839	174	5	did	do	AUX
admet-839	174	6	not	not	PART
admet-839	174	7	fully	fully	ADV
admet-839	174	8	crystallize	crystallize	VERB
admet-839	174	9	in	in	ADP
admet-839	174	10	80	80	NUM
admet-839	174	11	days	day	NOUN
admet-839	174	12	.	.	PUNCT
admet-839	175	1	in	in	ADP
admet-839	175	2	contrast	contrast	NOUN
admet-839	175	3	,	,	PUNCT
admet-839	175	4	on	on	ADP
admet-839	175	5	the	the	DET
admet-839	175	6	second	second	ADJ
admet-839	175	7	day	day	NOUN
admet-839	175	8	,	,	PUNCT
admet-839	175	9	spa	spa	NOUN
admet-839	175	10	detected	detect	VERB
admet-839	175	11	a	a	DET
admet-839	175	12	rapid	rapid	ADJ
admet-839	175	13	decrease	decrease	NOUN
admet-839	175	14	in	in	ADP
admet-839	175	15	solubility	solubility	NOUN
admet-839	175	16	towards	towards	ADP
admet-839	175	17	a	a	DET
admet-839	175	18	value	value	NOUN
admet-839	175	19	slightly	slightly	ADV
admet-839	175	20	above	above	ADP
admet-839	175	21	the	the	DET
admet-839	175	22	solubility	solubility	NOUN
admet-839	175	23	of	of	ADP
admet-839	175	24	the	the	DET
admet-839	175	25	γ	γ	PROPN
admet-839	175	26	form	form	NOUN
admet-839	175	27	.	.	PUNCT
admet-839	176	1	the	the	DET
admet-839	176	2	slightly	slightly	ADV
admet-839	176	3	higher	high	ADJ
admet-839	176	4	solubility	solubility	NOUN
admet-839	176	5	was	be	AUX
admet-839	176	6	most	most	ADV
admet-839	176	7	likely	likely	ADV
admet-839	176	8	measured	measure	VERB
admet-839	176	9	due	due	ADP
admet-839	176	10	to	to	ADP
admet-839	176	11	the	the	DET
admet-839	176	12	presence	presence	NOUN
admet-839	176	13	of	of	ADP
admet-839	176	14	crystals	crystal	NOUN
admet-839	176	15	with	with	ADP
admet-839	176	16	different	different	ADJ
admet-839	176	17	morphology	morphology	NOUN
admet-839	176	18	,	,	PUNCT
admet-839	176	19	nanocrystals	nanocrystal	NOUN
admet-839	176	20	,	,	PUNCT
admet-839	176	21	and	and	CCONJ
admet-839	176	22	some	some	DET
admet-839	176	23	associated	associated	ADJ
admet-839	176	24	residual	residual	ADJ
admet-839	176	25	disorder	disorder	NOUN
admet-839	176	26	on	on	ADP
admet-839	176	27	the	the	DET
admet-839	176	28	surface	surface	NOUN
admet-839	176	29	compared	compare	VERB
admet-839	176	30	to	to	ADP
admet-839	176	31	single	single	ADJ
admet-839	176	32	crystals	crystal	NOUN
admet-839	176	33	of	of	ADP
admet-839	176	34	the	the	DET
admet-839	176	35	reference	reference	NOUN
admet-839	176	36	γ	γ	NOUN
admet-839	176	37	form	form	NOUN
admet-839	176	38	.	.	PUNCT
admet-839	177	1	the	the	DET
admet-839	177	2	stability	stability	NOUN
admet-839	177	3	of	of	ADP
admet-839	177	4	an	an	DET
admet-839	177	5	amorphous	amorphous	ADJ
admet-839	177	6	material	material	NOUN
admet-839	177	7	approached	approach	VERB
admet-839	177	8	from	from	ADP
admet-839	177	9	the	the	DET
admet-839	177	10	solubility	solubility	NOUN
admet-839	177	11	perspective	perspective	NOUN
admet-839	177	12	,	,	PUNCT
admet-839	177	13	as	as	SCONJ
admet-839	177	14	enabled	enable	VERB
admet-839	177	15	with	with	ADP
admet-839	177	16	spa	spa	NOUN
admet-839	177	17	,	,	PUNCT
admet-839	177	18	directly	directly	ADV
admet-839	177	19	reflects	reflect	VERB
admet-839	177	20	the	the	DET
admet-839	177	21	changes	change	NOUN
admet-839	177	22	occurring	occur	VERB
admet-839	177	23	on	on	ADP
admet-839	177	24	particle	particle	NOUN
admet-839	177	25	surfaces	surface	NOUN
admet-839	177	26	that	that	PRON
admet-839	177	27	dictate	dictate	VERB
admet-839	177	28	the	the	DET
admet-839	177	29	dissolution	dissolution	ADJ
admet-839	177	30	behaviour	behaviour	NOUN
admet-839	177	31	.	.	PUNCT
admet-839	178	1	this	this	DET
admet-839	178	2	straight	straight	ADJ
admet-839	178	3	-	-	PUNCT
admet-839	178	4	forward	forward	NOUN
admet-839	178	5	and	and	CCONJ
admet-839	178	6	sensitive	sensitive	ADJ
admet-839	178	7	approach	approach	NOUN
admet-839	178	8	could	could	AUX
admet-839	178	9	provide	provide	VERB
admet-839	178	10	crucial	crucial	ADJ
admet-839	178	11	information	information	NOUN
admet-839	178	12	for	for	ADP
admet-839	178	13	better	well	ADJ
admet-839	178	14	understanding	understanding	NOUN
admet-839	178	15	of	of	ADP
admet-839	178	16	the	the	DET
admet-839	178	17	link	link	NOUN
admet-839	178	18	between	between	ADP
admet-839	178	19	stability	stability	NOUN
admet-839	178	20	of	of	ADP
admet-839	178	21	amorphous	amorphous	ADJ
admet-839	178	22	,	,	PUNCT
admet-839	178	23	and	and	CCONJ
admet-839	178	24	also	also	ADV
admet-839	178	25	other	other	ADJ
admet-839	178	26	,	,	PUNCT
admet-839	178	27	materials	material	NOUN
admet-839	178	28	,	,	PUNCT
admet-839	178	29	their	their	PRON
admet-839	178	30	solubility	solubility	NOUN
admet-839	178	31	and	and	CCONJ
admet-839	178	32	in	in	ADP
admet-839	178	33	vivo	vivo	ADJ
admet-839	178	34	performance	performance	NOUN
admet-839	178	35	,	,	PUNCT
admet-839	178	36	which	which	PRON
admet-839	178	37	is	be	AUX
admet-839	178	38	especially	especially	ADV
admet-839	178	39	important	important	ADJ
admet-839	178	40	in	in	ADP
admet-839	178	41	pharmaceutical	pharmaceutical	ADJ
admet-839	178	42	science	science	NOUN
admet-839	178	43	.	.	PUNCT
admet-839	179	1	acknowledgements	acknowledgement	NOUN
admet-839	179	2	:	:	PUNCT
admet-839	179	3	j.š	j.š	PROPN
admet-839	179	4	.	.	PROPN
admet-839	179	5	acknowledges	acknowledge	VERB
admet-839	179	6	doctoral	doctoral	ADJ
admet-839	179	7	programme	programme	NOUN
admet-839	179	8	in	in	ADP
admet-839	179	9	drug	drug	NOUN
admet-839	179	10	research	research	NOUN
admet-839	179	11	(	(	PUNCT
admet-839	179	12	dpdr	dpdr	NOUN
admet-839	179	13	)	)	PUNCT
admet-839	179	14	funding	funding	NOUN
admet-839	179	15	.	.	PUNCT
admet-839	180	1	conflict	conflict	NOUN
admet-839	180	2	of	of	ADP
admet-839	180	3	interest	interest	NOUN
admet-839	180	4	:	:	PUNCT
admet-839	180	5	j.š	j.š	PROPN
admet-839	180	6	.	.	PROPN
admet-839	180	7	,	,	PUNCT
admet-839	180	8	m.a	m.a	PROPN
admet-839	180	9	.	.	PROPN
admet-839	180	10	,	,	PUNCT
admet-839	180	11	j.y	j.y	PROPN
admet-839	180	12	.	.	PROPN
admet-839	180	13	and	and	CCONJ
admet-839	180	14	s.s	s.s	PROPN
admet-839	180	15	.	.	PROPN
admet-839	180	16	are	be	AUX
admet-839	180	17	shareholders	shareholder	NOUN
admet-839	180	18	of	of	ADP
admet-839	180	19	the	the	DET
admet-839	180	20	solubility	solubility	NOUN
admet-839	180	21	company	company	NOUN
admet-839	180	22	oy	oy	NOUN
admet-839	180	23	that	that	PRON
admet-839	180	24	owns	own	VERB
admet-839	180	25	the	the	DET
admet-839	180	26	intellectual	intellectual	ADJ
admet-839	180	27	property	property	NOUN
admet-839	180	28	rights	right	NOUN
admet-839	180	29	to	to	ADP
admet-839	180	30	the	the	DET
admet-839	180	31	spa	spa	NOUN
admet-839	180	32	method	method	NOUN
admet-839	180	33	.	.	PUNCT
admet-839	181	1	references	reference	NOUN
admet-839	181	2	[	[	X
admet-839	181	3	1	1	NUM
admet-839	181	4	]	]	X
admet-839	181	5	b.c	b.c	PROPN
admet-839	181	6	.	.	PROPN
admet-839	181	7	hancock	hancock	PROPN
admet-839	181	8	,	,	PUNCT
admet-839	181	9	m.	m.	NOUN
admet-839	181	10	parks	park	NOUN
admet-839	181	11	.	.	PUNCT
admet-839	182	1	what	what	PRON
admet-839	182	2	is	be	AUX
admet-839	182	3	the	the	DET
admet-839	182	4	true	true	ADJ
admet-839	182	5	solubility	solubility	NOUN
admet-839	182	6	advantage	advantage	NOUN
admet-839	182	7	for	for	ADP
admet-839	182	8	amorphous	amorphous	ADJ
admet-839	182	9	pharmaceuticals	pharmaceutical	NOUN
admet-839	182	10	?	?	PUNCT
admet-839	182	11	.	.	PUNCT
admet-839	183	1	pharm	pharm	PROPN
admet-839	183	2	.	.	PUNCT
admet-839	184	1	res	re	NOUN
admet-839	184	2	.	.	PROPN
admet-839	185	1	17	17	NUM
admet-839	185	2	(	(	PUNCT
admet-839	185	3	2000	2000	NUM
admet-839	185	4	)	)	PUNCT
admet-839	186	1	397–404	397–404	NUM
admet-839	186	2	.	.	PUNCT
admet-839	187	1	[	[	X
admet-839	187	2	2	2	NUM
admet-839	187	3	]	]	X
admet-839	187	4	s.b	s.b	PROPN
admet-839	187	5	.	.	PROPN
admet-839	187	6	murdande	murdande	PROPN
admet-839	187	7	,	,	PUNCT
admet-839	187	8	m.j	m.j	PROPN
admet-839	187	9	.	.	PROPN
admet-839	187	10	pikal	pikal	PROPN
admet-839	187	11	,	,	PUNCT
admet-839	187	12	r.m	r.m	PROPN
admet-839	187	13	.	.	PROPN
admet-839	187	14	shanker	shanker	PROPN
admet-839	187	15	,	,	PUNCT
admet-839	187	16	r.h	r.h	PROPN
admet-839	187	17	.	.	PROPN
admet-839	187	18	bogner	bogner	PROPN
admet-839	187	19	.	.	PUNCT
admet-839	188	1	solubility	solubility	NOUN
admet-839	188	2	advantage	advantage	NOUN
admet-839	188	3	of	of	ADP
admet-839	188	4	amorphous	amorphous	ADJ
admet-839	188	5	pharmaceuticals	pharmaceutical	NOUN
admet-839	188	6	:	:	PUNCT
admet-839	188	7	i.	i.	NOUN
admet-839	188	8	a	a	DET
admet-839	188	9	thermodynamic	thermodynamic	ADJ
admet-839	188	10	analysis	analysis	NOUN
admet-839	188	11	.	.	PUNCT
admet-839	189	1	j.	j.	PROPN
admet-839	189	2	pharm	pharm	PROPN
admet-839	189	3	.	.	PUNCT
admet-839	190	1	sci	sci	PROPN
admet-839	190	2	.	.	PROPN
admet-839	191	1	99	99	NUM
admet-839	191	2	(	(	PUNCT
admet-839	191	3	2010	2010	NUM
admet-839	191	4	)	)	PUNCT
admet-839	191	5	1255–1263	1255–1263	NUM
admet-839	191	6	.	.	PUNCT
admet-839	192	1	[	[	X
admet-839	192	2	3	3	X
admet-839	192	3	]	]	X
admet-839	192	4	s.b	s.b	PROPN
admet-839	192	5	.	.	PROPN
admet-839	192	6	murdande	murdande	PROPN
admet-839	192	7	,	,	PUNCT
admet-839	192	8	m.j	m.j	PROPN
admet-839	192	9	.	.	PROPN
admet-839	192	10	pikal	pikal	PROPN
admet-839	192	11	,	,	PUNCT
admet-839	192	12	r.m	r.m	PROPN
admet-839	192	13	.	.	PROPN
admet-839	192	14	shanker	shanker	PROPN
admet-839	192	15	,	,	PUNCT
admet-839	192	16	r.h	r.h	PROPN
admet-839	192	17	.	.	PROPN
admet-839	192	18	bogner	bogner	PROPN
admet-839	192	19	.	.	PUNCT
admet-839	193	1	solubility	solubility	NOUN
admet-839	193	2	advantage	advantage	NOUN
admet-839	193	3	of	of	ADP
admet-839	193	4	amorphous	amorphous	ADJ
admet-839	193	5	pharmaceuticals	pharmaceutical	NOUN
admet-839	193	6	:	:	PUNCT
admet-839	193	7	ii	ii	PROPN
admet-839	193	8	.	.	PUNCT
admet-839	194	1	application	application	NOUN
admet-839	194	2	of	of	ADP
admet-839	194	3	quantitative	quantitative	ADJ
admet-839	194	4	thermodynamic	thermodynamic	ADJ
admet-839	194	5	relationships	relationship	NOUN
admet-839	194	6	for	for	ADP
admet-839	194	7	prediction	prediction	NOUN
admet-839	194	8	of	of	ADP
admet-839	194	9	solubility	solubility	NOUN
admet-839	194	10	enhancement	enhancement	NOUN
admet-839	194	11	in	in	ADP
admet-839	194	12	structurally	structurally	ADV
admet-839	194	13	diverse	diverse	ADJ
admet-839	194	14	insoluble	insoluble	ADJ
admet-839	194	15	pharmaceuticals	pharmaceutical	NOUN
admet-839	194	16	.	.	PUNCT
admet-839	195	1	pharm	pharm	NOUN
admet-839	195	2	.	.	PUNCT
admet-839	196	1	res	re	NOUN
admet-839	196	2	.	.	PROPN
admet-839	197	1	27	27	NUM
admet-839	197	2	(	(	PUNCT
admet-839	197	3	2010	2010	NUM
admet-839	197	4	)	)	PUNCT
admet-839	197	5	2704–2714	2704–2714	NUM
admet-839	197	6	.	.	PUNCT
admet-839	198	1	[	[	X
admet-839	198	2	4	4	NUM
admet-839	198	3	]	]	PUNCT
admet-839	198	4	l.	l.	PROPN
admet-839	198	5	borka	borka	PROPN
admet-839	198	6	.	.	PUNCT
admet-839	199	1	the	the	DET
admet-839	199	2	polymorphism	polymorphism	NOUN
admet-839	199	3	of	of	ADP
admet-839	199	4	indomethacine	indomethacine	NOUN
admet-839	199	5	.	.	PUNCT
admet-839	200	1	new	new	ADJ
admet-839	200	2	modifications	modification	NOUN
admet-839	200	3	,	,	PUNCT
admet-839	200	4	their	their	PRON
admet-839	200	5	melting	melt	VERB
admet-839	200	6	behavior	behavior	NOUN
admet-839	200	7	and	and	CCONJ
admet-839	200	8	solubility	solubility	NOUN
admet-839	200	9	.	.	PUNCT
admet-839	201	1	acta	acta	PROPN
admet-839	201	2	pharm	pharm	PROPN
admet-839	201	3	.	.	PUNCT
admet-839	202	1	suec	suec	PROPN
admet-839	202	2	.	.	PROPN
admet-839	202	3	11	11	NUM
admet-839	202	4	(	(	PUNCT
admet-839	202	5	1974	1974	NUM
admet-839	202	6	)	)	PUNCT
admet-839	202	7	295–303	295–303	NUM
admet-839	202	8	.	.	PUNCT
admet-839	203	1	[	[	X
admet-839	203	2	5	5	X
admet-839	203	3	]	]	PUNCT
admet-839	203	4	h.	h.	PROPN
admet-839	203	5	imaizumi	imaizumi	PROPN
admet-839	203	6	,	,	PUNCT
admet-839	203	7	n.	n.	PROPN
admet-839	203	8	nambu	nambu	PROPN
admet-839	203	9	,	,	PUNCT
admet-839	203	10	t.	t.	PROPN
admet-839	203	11	nagai	nagai	PROPN
admet-839	203	12	.	.	PUNCT
admet-839	204	1	stability	stability	NOUN
admet-839	204	2	and	and	CCONJ
admet-839	204	3	several	several	ADJ
admet-839	204	4	physical	physical	ADJ
admet-839	204	5	properties	property	NOUN
admet-839	204	6	of	of	ADP
admet-839	204	7	amorphous	amorphous	ADJ
admet-839	204	8	and	and	CCONJ
admet-839	204	9	crystalline	crystalline	ADJ
admet-839	204	10	forms	form	NOUN
admet-839	204	11	of	of	ADP
admet-839	204	12	indomethacin	indomethacin	NOUN
admet-839	204	13	.	.	PUNCT
admet-839	205	1	chem	chem	PROPN
admet-839	205	2	.	.	PUNCT
admet-839	206	1	pharm	pharm	NOUN
admet-839	206	2	.	.	PUNCT
admet-839	207	1	bull	bull	NOUN
admet-839	207	2	.	.	PUNCT
admet-839	208	1	28	28	NUM
admet-839	209	1	(	(	PUNCT
admet-839	209	2	1979	1979	NUM
admet-839	209	3	)	)	PUNCT
admet-839	209	4	2565–2569	2565–2569	NUM
admet-839	209	5	.	.	PUNCT
admet-839	210	1	[	[	X
admet-839	210	2	6	6	NUM
admet-839	210	3	]	]	PUNCT
admet-839	210	4	v.	v.	ADP
admet-839	210	5	andronis	andronis	NOUN
admet-839	210	6	,	,	PUNCT
admet-839	210	7	m.	m.	NOUN
admet-839	210	8	yoshioka	yoshioka	PROPN
admet-839	210	9	,	,	PUNCT
admet-839	210	10	g.	g.	PROPN
admet-839	210	11	zografi	zografi	PROPN
admet-839	210	12	.	.	PUNCT
admet-839	211	1	effects	effect	NOUN
admet-839	211	2	of	of	ADP
admet-839	211	3	sorbed	sorb	VERB
admet-839	211	4	water	water	NOUN
admet-839	211	5	on	on	ADP
admet-839	211	6	the	the	DET
admet-839	211	7	crystallization	crystallization	NOUN
admet-839	211	8	of	of	ADP
admet-839	211	9	indomethacin	indomethacin	NOUN
admet-839	211	10	from	from	ADP
admet-839	211	11	the	the	DET
admet-839	211	12	amorphous	amorphous	ADJ
admet-839	211	13	state	state	NOUN
admet-839	211	14	.	.	PUNCT
admet-839	212	1	j.	j.	PROPN
admet-839	212	2	pharm	pharm	PROPN
admet-839	212	3	.	.	PUNCT
admet-839	213	1	sci	sci	PROPN
admet-839	213	2	.	.	PROPN
admet-839	214	1	86	86	NUM
admet-839	214	2	(	(	PUNCT
admet-839	214	3	1997	1997	NUM
admet-839	214	4	)	)	PUNCT
admet-839	214	5	346–357	346–357	NUM
admet-839	214	6	.	.	PUNCT
admet-839	215	1	[	[	X
admet-839	215	2	7	7	X
admet-839	215	3	]	]	X
admet-839	215	4	v.	v.	ADP
admet-839	215	5	andronis	andronis	NOUN
admet-839	215	6	,	,	PUNCT
admet-839	215	7	g.	g.	PROPN
admet-839	215	8	zografi	zografi	PROPN
admet-839	215	9	.	.	PUNCT
admet-839	216	1	crystal	crystal	NOUN
admet-839	216	2	nucleation	nucleation	NOUN
admet-839	216	3	and	and	CCONJ
admet-839	216	4	growth	growth	NOUN
admet-839	216	5	of	of	ADP
admet-839	216	6	indomethacin	indomethacin	ADJ
admet-839	216	7	polymorphs	polymorphs	NOUN
admet-839	216	8	from	from	ADP
admet-839	216	9	the	the	DET
admet-839	216	10	amorphous	amorphous	ADJ
admet-839	216	11	state	state	NOUN
admet-839	216	12	.	.	PUNCT
admet-839	217	1	j.	j.	PROPN
admet-839	217	2	non	non	PROPN
admet-839	217	3	.	.	PROPN
admet-839	217	4	cryst	cryst	PROPN
admet-839	217	5	.	.	PUNCT
admet-839	218	1	solids	solid	NOUN
admet-839	218	2	.	.	PUNCT
admet-839	219	1	271	271	NUM
admet-839	219	2	(	(	PUNCT
admet-839	219	3	2000	2000	NUM
admet-839	219	4	)	)	PUNCT
admet-839	220	1	236–248	236–248	NUM
admet-839	220	2	.	.	PUNCT
admet-839	221	1	[	[	X
admet-839	221	2	8	8	NUM
admet-839	221	3	]	]	PUNCT
admet-839	221	4	t.	t.	PROPN
admet-839	221	5	wu	wu	PROPN
admet-839	221	6	,	,	PUNCT
admet-839	221	7	l.	l.	PROPN
admet-839	221	8	yu	yu	PROPN
admet-839	221	9	.	.	PUNCT
admet-839	221	10	surface	surface	NOUN
admet-839	221	11	crystallization	crystallization	NOUN
admet-839	221	12	of	of	ADP
admet-839	221	13	indomethacin	indomethacin	NOUN
admet-839	221	14	below	below	ADP
admet-839	221	15	tg	tg	PROPN
admet-839	221	16	.	.	PUNCT
admet-839	222	1	pharm	pharm	PROPN
admet-839	222	2	.	.	PUNCT
admet-839	223	1	res	re	NOUN
admet-839	223	2	.	.	PUNCT
admet-839	224	1	23	23	NUM
admet-839	224	2	(	(	PUNCT
admet-839	224	3	2006	2006	NUM
admet-839	224	4	)	)	PUNCT
admet-839	224	5	2350–2355	2350–2355	NUM
admet-839	224	6	.	.	PUNCT
admet-839	225	1	[	[	X
admet-839	225	2	9	9	NUM
admet-839	225	3	]	]	X
admet-839	225	4	d.e	d.e	PROPN
admet-839	225	5	.	.	PROPN
admet-839	225	6	alonzo	alonzo	PROPN
admet-839	225	7	,	,	PUNCT
admet-839	225	8	g.g	g.g	PROPN
admet-839	225	9	.	.	PROPN
admet-839	225	10	z.	z.	PROPN
admet-839	225	11	zhang	zhang	PROPN
admet-839	225	12	,	,	PUNCT
admet-839	225	13	d.	d.	PROPN
admet-839	225	14	zhou	zhou	PROPN
admet-839	225	15	,	,	PUNCT
admet-839	225	16	y.	y.	PROPN
admet-839	225	17	gao	gao	PROPN
admet-839	225	18	,	,	PUNCT
admet-839	225	19	l.s	l.s	PROPN
admet-839	225	20	.	.	PROPN
admet-839	225	21	taylor	taylor	PROPN
admet-839	225	22	.	.	PUNCT
admet-839	226	1	understanding	understand	VERB
admet-839	226	2	the	the	DET
admet-839	226	3	behavior	behavior	NOUN
admet-839	226	4	of	of	ADP
admet-839	226	5	amorphous	amorphous	ADJ
admet-839	226	6	pharmaceutical	pharmaceutical	NOUN
admet-839	226	7	systems	system	NOUN
admet-839	226	8	during	during	ADP
admet-839	226	9	dissolution	dissolution	NOUN
admet-839	226	10	.	.	PUNCT
admet-839	227	1	pharm	pharm	NOUN
admet-839	227	2	.	.	PUNCT
admet-839	228	1	res	re	NOUN
admet-839	228	2	.	.	PROPN
admet-839	229	1	27	27	NUM
admet-839	229	2	(	(	PUNCT
admet-839	229	3	2010	2010	NUM
admet-839	229	4	)	)	PUNCT
admet-839	230	1	608–618	608–618	NUM
admet-839	230	2	.	.	PUNCT
admet-839	231	1	[	[	X
admet-839	231	2	10	10	NUM
admet-839	231	3	]	]	X
admet-839	231	4	v.	v.	CCONJ
admet-839	231	5	andronis	andronis	NOUN
admet-839	231	6	,	,	PUNCT
admet-839	231	7	g.	g.	PROPN
admet-839	231	8	zografi	zografi	PROPN
admet-839	231	9	.	.	PUNCT
admet-839	232	1	the	the	DET
admet-839	232	2	molecular	molecular	ADJ
admet-839	232	3	mobility	mobility	NOUN
admet-839	232	4	of	of	ADP
admet-839	232	5	supercooled	supercoole	VERB
admet-839	232	6	amorphous	amorphous	ADJ
admet-839	232	7	indomethacin	indomethacin	NOUN
admet-839	232	8	as	as	ADP
admet-839	232	9	a	a	DET
admet-839	232	10	function	function	NOUN
admet-839	232	11	of	of	ADP
admet-839	232	12	temperature	temperature	NOUN
admet-839	232	13	and	and	CCONJ
admet-839	232	14	relative	relative	ADJ
admet-839	232	15	humidity	humidity	NOUN
admet-839	232	16	.	.	PUNCT
admet-839	233	1	pharm	pharm	NOUN
admet-839	233	2	.	.	PUNCT
admet-839	234	1	res	re	NOUN
admet-839	234	2	.	.	PROPN
admet-839	235	1	15	15	NUM
admet-839	235	2	(	(	PUNCT
admet-839	235	3	1998	1998	NUM
admet-839	235	4	)	)	PUNCT
admet-839	236	1	835–842	835–842	NUM
admet-839	236	2	.	.	PUNCT
admet-839	237	1	admet	admet	PROPN
admet-839	237	2	&	&	CCONJ
admet-839	237	3	dmpk	dmpk	PROPN
admet-839	237	4	8(4	8(4	NOUN
admet-839	237	5	)	)	PUNCT
admet-839	237	6	(	(	PUNCT
admet-839	237	7	2020	2020	NUM
admet-839	237	8	)	)	PUNCT
admet-839	237	9	401	401	NUM
admet-839	237	10	-	-	SYM
admet-839	237	11	409	409	NUM
admet-839	237	12	amorphous	amorphous	ADJ
admet-839	237	13	solubility	solubility	NOUN
admet-839	237	14	over	over	ADP
admet-839	237	15	time	time	NOUN
admet-839	237	16	doi	doi	PROPN
admet-839	237	17	:	:	PUNCT
admet-839	237	18	https://dx.doi.org/10.5599/admet.839	https://dx.doi.org/10.5599/admet.839	NOUN
admet-839	237	19	409	409	NUM
admet-839	238	1	[	[	SYM
admet-839	238	2	11	11	NUM
admet-839	238	3	]	]	PUNCT
admet-839	238	4	m.	m.	NOUN
admet-839	238	5	savolainen	savolainen	PROPN
admet-839	238	6	k.	k.	PROPN
admet-839	238	7	kogermann	kogermann	PROPN
admet-839	238	8	,	,	PUNCT
admet-839	238	9	a.	a.	PROPN
admet-839	238	10	heinz	heinz	PROPN
admet-839	238	11	,	,	PUNCT
admet-839	238	12	j.	j.	PROPN
admet-839	238	13	aaltonen	aaltonen	PROPN
admet-839	238	14	,	,	PUNCT
admet-839	238	15	l.	l.	PROPN
admet-839	238	16	peltonen	peltonen	PROPN
admet-839	238	17	,	,	PUNCT
admet-839	238	18	c.	c.	PROPN
admet-839	238	19	strachan	strachan	PROPN
admet-839	238	20	,	,	PUNCT
admet-839	238	21	j.	j.	PROPN
admet-839	238	22	yliruusi	yliruusi	PROPN
admet-839	238	23	.	.	PUNCT
admet-839	239	1	better	well	ADJ
admet-839	239	2	understanding	understanding	NOUN
admet-839	239	3	of	of	ADP
admet-839	239	4	dissolution	dissolution	ADJ
admet-839	239	5	behaviour	behaviour	NOUN
admet-839	239	6	of	of	ADP
admet-839	239	7	amorphous	amorphous	ADJ
admet-839	239	8	drugs	drug	NOUN
admet-839	239	9	by	by	ADP
admet-839	239	10	in	in	ADP
admet-839	239	11	situ	situ	ADJ
admet-839	239	12	solid	solid	ADJ
admet-839	239	13	-	-	PUNCT
admet-839	239	14	state	state	NOUN
admet-839	239	15	analysis	analysis	NOUN
admet-839	239	16	using	use	VERB
admet-839	239	17	raman	raman	NOUN
admet-839	239	18	spectroscopy	spectroscopy	NOUN
admet-839	239	19	.	.	PUNCT
admet-839	240	1	eur	eur	PROPN
admet-839	240	2	.	.	PUNCT
admet-839	241	1	j.	j.	PROPN
admet-839	241	2	pharm	pharm	PROPN
admet-839	241	3	.	.	PUNCT
admet-839	242	1	biopharm	biopharm	PROPN
admet-839	242	2	.	.	PUNCT
admet-839	243	1	71	71	NUM
admet-839	243	2	(	(	PUNCT
admet-839	243	3	2009	2009	NUM
admet-839	243	4	)	)	PUNCT
admet-839	244	1	71–79	71–79	ADV
admet-839	244	2	.	.	PUNCT
admet-839	245	1	[	[	X
admet-839	245	2	12	12	NUM
admet-839	245	3	]	]	PUNCT
admet-839	245	4	k.	k.	PROPN
admet-839	245	5	greco	greco	PROPN
admet-839	245	6	,	,	PUNCT
admet-839	245	7	r.	r.	PROPN
admet-839	245	8	bogner	bogner	PROPN
admet-839	245	9	.	.	PUNCT
admet-839	246	1	crystallization	crystallization	NOUN
admet-839	246	2	of	of	ADP
admet-839	246	3	amorphous	amorphous	ADJ
admet-839	246	4	indomethacin	indomethacin	NOUN
admet-839	246	5	during	during	ADP
admet-839	246	6	dissolution	dissolution	NOUN
admet-839	246	7	:	:	PUNCT
admet-839	246	8	effect	effect	NOUN
admet-839	246	9	of	of	ADP
admet-839	246	10	processing	processing	NOUN
admet-839	246	11	and	and	CCONJ
admet-839	246	12	annealing	annealing	NOUN
admet-839	246	13	.	.	PUNCT
admet-839	247	1	mol	mol	PROPN
admet-839	247	2	.	.	PUNCT
admet-839	247	3	pharm	pharm	PROPN
admet-839	247	4	.	.	PUNCT
admet-839	248	1	7	7	NUM
admet-839	248	2	(	(	PUNCT
admet-839	248	3	2010	2010	NUM
admet-839	248	4	)	)	PUNCT
admet-839	248	5	1406–1418	1406–1418	NUM
admet-839	248	6	.	.	PUNCT
admet-839	249	1	[	[	X
admet-839	249	2	13	13	NUM
admet-839	249	3	]	]	X
admet-839	249	4	p.a	p.a	PROPN
admet-839	249	5	.	.	PROPN
admet-839	249	6	priemel	priemel	PROPN
admet-839	249	7	,	,	PUNCT
admet-839	249	8	h.	h.	PROPN
admet-839	249	9	grohganz	grohganz	PROPN
admet-839	249	10	,	,	PUNCT
admet-839	249	11	k.c	k.c	PROPN
admet-839	249	12	.	.	PROPN
admet-839	249	13	gordon	gordon	PROPN
admet-839	249	14	,	,	PUNCT
admet-839	249	15	t.	t.	PROPN
admet-839	249	16	rades	rades	PROPN
admet-839	249	17	,	,	PUNCT
admet-839	249	18	c.j	c.j	PROPN
admet-839	249	19	.	.	PROPN
admet-839	249	20	strachan	strachan	PROPN
admet-839	249	21	.	.	PUNCT
admet-839	250	1	the	the	DET
admet-839	250	2	impact	impact	NOUN
admet-839	250	3	of	of	ADP
admet-839	250	4	surfaceand	surfaceand	NOUN
admet-839	250	5	nanocrystallisation	nanocrystallisation	NOUN
admet-839	250	6	on	on	ADP
admet-839	250	7	the	the	DET
admet-839	250	8	detected	detect	VERB
admet-839	250	9	amorphous	amorphous	ADJ
admet-839	250	10	content	content	NOUN
admet-839	250	11	and	and	CCONJ
admet-839	250	12	the	the	DET
admet-839	250	13	dissolution	dissolution	ADJ
admet-839	250	14	behaviour	behaviour	NOUN
admet-839	250	15	of	of	ADP
admet-839	250	16	amorphous	amorphous	ADJ
admet-839	250	17	indomethacin	indomethacin	NOUN
admet-839	250	18	.	.	PUNCT
admet-839	251	1	eur	eur	PROPN
admet-839	251	2	.	.	PUNCT
admet-839	252	1	j.	j.	PROPN
admet-839	252	2	pharm	pharm	PROPN
admet-839	252	3	.	.	PUNCT
admet-839	253	1	biopharm	biopharm	PROPN
admet-839	253	2	.	.	PUNCT
admet-839	254	1	82	82	NUM
admet-839	254	2	(	(	PUNCT
admet-839	254	3	2012	2012	NUM
admet-839	254	4	)	)	PUNCT
admet-839	255	1	187–193	187–193	NUM
admet-839	255	2	.	.	PUNCT
admet-839	256	1	[	[	X
admet-839	256	2	14	14	NUM
admet-839	256	3	]	]	X
admet-839	256	4	d.	d.	PROPN
admet-839	256	5	novakovic	novakovic	PROPN
admet-839	256	6	,	,	PUNCT
admet-839	256	7	a.	a.	NOUN
admet-839	256	8	isomäki	isomäki	NOUN
admet-839	256	9	,	,	PUNCT
admet-839	256	10	b.	b.	PROPN
admet-839	256	11	pleunis	pleunis	PROPN
admet-839	256	12	,	,	PUNCT
admet-839	256	13	s.j	s.j	PROPN
admet-839	256	14	.	.	PROPN
admet-839	256	15	fraser	fraser	PROPN
admet-839	256	16	-	-	PUNCT
admet-839	256	17	miller	miller	PROPN
admet-839	256	18	,	,	PUNCT
admet-839	256	19	l.	l.	PROPN
admet-839	256	20	peltonen	peltonen	PROPN
admet-839	256	21	,	,	PUNCT
admet-839	256	22	t.	t.	PROPN
admet-839	256	23	laaksonen	laaksonen	PROPN
admet-839	256	24	,	,	PUNCT
admet-839	256	25	c.j	c.j	PROPN
admet-839	256	26	.	.	PROPN
admet-839	256	27	strachan	strachan	PROPN
admet-839	256	28	.	.	PUNCT
admet-839	257	1	understanding	understand	VERB
admet-839	257	2	dissolution	dissolution	NOUN
admet-839	257	3	and	and	CCONJ
admet-839	257	4	crystallization	crystallization	NOUN
admet-839	257	5	with	with	ADP
admet-839	257	6	imaging	imaging	NOUN
admet-839	257	7	 	 	SPACE
admet-839	257	8	:	:	PUNCT
admet-839	257	9	a	a	DET
admet-839	257	10	surface	surface	NOUN
admet-839	257	11	point	point	NOUN
admet-839	257	12	of	of	ADP
admet-839	257	13	view	view	NOUN
admet-839	257	14	.	.	PUNCT
admet-839	258	1	mol	mol	X
admet-839	258	2	.	.	PUNCT
admet-839	258	3	pharm	pharm	PROPN
admet-839	258	4	.	.	PUNCT
admet-839	259	1	15	15	NUM
admet-839	259	2	(	(	PUNCT
admet-839	259	3	2018	2018	NUM
admet-839	259	4	)	)	PUNCT
admet-839	259	5	5361–5373	5361–5373	NUM
admet-839	259	6	.	.	PUNCT
admet-839	260	1	[	[	X
admet-839	260	2	15	15	NUM
admet-839	260	3	]	]	X
admet-839	260	4	d.	d.	PROPN
admet-839	260	5	novakovic	novakovic	PROPN
admet-839	260	6	,	,	PUNCT
admet-839	260	7	l.	l.	PROPN
admet-839	260	8	peltonen	peltonen	PROPN
admet-839	260	9	,	,	PUNCT
admet-839	260	10	a.	a.	NOUN
admet-839	260	11	isomäki	isomäki	NOUN
admet-839	260	12	,	,	PUNCT
admet-839	260	13	s.	s.	PROPN
admet-839	260	14	j.	j.	PROPN
admet-839	260	15	fraser	fraser	PROPN
admet-839	260	16	-	-	PUNCT
admet-839	260	17	miller	miller	PROPN
admet-839	260	18	,	,	PUNCT
admet-839	260	19	l.	l.	PROPN
admet-839	260	20	h.	h.	PROPN
admet-839	260	21	nielsen	nielsen	PROPN
admet-839	260	22	,	,	PUNCT
admet-839	260	23	t.	t.	PROPN
admet-839	260	24	laaksonen	laaksonen	PROPN
admet-839	260	25	,	,	PUNCT
admet-839	260	26	c.	c.	PROPN
admet-839	260	27	j.	j.	PROPN
admet-839	260	28	strachan	strachan	PROPN
admet-839	260	29	.	.	PUNCT
admet-839	260	30	surface	surface	PROPN
admet-839	260	31	stabilization	stabilization	NOUN
admet-839	260	32	and	and	CCONJ
admet-839	260	33	dissolution	dissolution	NOUN
admet-839	260	34	rate	rate	NOUN
admet-839	260	35	improvement	improvement	NOUN
admet-839	260	36	of	of	ADP
admet-839	260	37	amorphous	amorphous	ADJ
admet-839	260	38	compacts	compact	NOUN
admet-839	260	39	with	with	ADP
admet-839	260	40	thin	thin	ADJ
admet-839	260	41	polymer	polymer	NOUN
admet-839	260	42	coatings	coating	NOUN
admet-839	260	43	:	:	PUNCT
admet-839	260	44	can	can	AUX
admet-839	260	45	we	we	PRON
admet-839	260	46	have	have	VERB
admet-839	260	47	it	it	PRON
admet-839	260	48	all	all	PRON
admet-839	260	49	?	?	PUNCT
admet-839	260	50	.	.	PUNCT
admet-839	261	1	mol	mol	PROPN
admet-839	261	2	.	.	PUNCT
admet-839	261	3	pharm	pharm	PROPN
admet-839	261	4	.	.	PUNCT
admet-839	262	1	17	17	NUM
admet-839	262	2	(	(	PUNCT
admet-839	262	3	2020	2020	NUM
admet-839	262	4	)	)	PUNCT
admet-839	262	5	1248	1248	NUM
admet-839	262	6	-	-	SYM
admet-839	262	7	1260	1260	NUM
admet-839	262	8	.	.	PUNCT
admet-839	263	1	[	[	X
admet-839	263	2	16	16	NUM
admet-839	263	3	]	]	X
admet-839	263	4	s.b	s.b	PROPN
admet-839	263	5	.	.	PROPN
admet-839	263	6	murdande	murdande	PROPN
admet-839	263	7	,	,	PUNCT
admet-839	263	8	m.j	m.j	PROPN
admet-839	263	9	.	.	PROPN
admet-839	263	10	pikal	pikal	PROPN
admet-839	263	11	,	,	PUNCT
admet-839	263	12	r.m	r.m	PROPN
admet-839	263	13	.	.	PROPN
admet-839	263	14	shanker	shanker	PROPN
admet-839	263	15	,	,	PUNCT
admet-839	263	16	r.h	r.h	PROPN
admet-839	263	17	.	.	PROPN
admet-839	263	18	bogner	bogner	PROPN
admet-839	263	19	.	.	PUNCT
admet-839	264	1	aqueous	aqueous	ADJ
admet-839	264	2	solubility	solubility	NOUN
admet-839	264	3	of	of	ADP
admet-839	264	4	crystalline	crystalline	NOUN
admet-839	264	5	and	and	CCONJ
admet-839	264	6	amorphous	amorphous	ADJ
admet-839	264	7	drugs	drug	NOUN
admet-839	264	8	:	:	PUNCT
admet-839	264	9	challenges	challenge	NOUN
admet-839	264	10	in	in	ADP
admet-839	264	11	measurement	measurement	NOUN
admet-839	264	12	.	.	PUNCT
admet-839	265	1	pharm	pharm	PROPN
admet-839	265	2	.	.	PUNCT
admet-839	266	1	dev	dev	PROPN
admet-839	266	2	.	.	PUNCT
admet-839	266	3	technol	technol	PROPN
admet-839	266	4	.	.	PUNCT
admet-839	267	1	16	16	NUM
admet-839	267	2	(	(	PUNCT
admet-839	267	3	2011	2011	NUM
admet-839	267	4	)	)	PUNCT
admet-839	268	1	187–200	187–200	NUM
admet-839	268	2	.	.	PUNCT
admet-839	269	1	[	[	X
admet-839	269	2	17	17	NUM
admet-839	269	3	]	]	X
admet-839	269	4	s.	s.	PROPN
admet-839	269	5	svanbäck	svanbäck	PROPN
admet-839	269	6	,	,	PUNCT
admet-839	269	7	h.	h.	PROPN
admet-839	269	8	ehlers	ehlers	PROPN
admet-839	269	9	,	,	PUNCT
admet-839	269	10	o.	o.	PROPN
admet-839	269	11	antikainen	antikainen	PROPN
admet-839	269	12	,	,	PUNCT
admet-839	269	13	j.	j.	PROPN
admet-839	269	14	yliruusi	yliruusi	PROPN
admet-839	269	15	.	.	PUNCT
admet-839	270	1	on	on	ADP
admet-839	270	2	-	-	PUNCT
admet-839	270	3	chip	chip	NOUN
admet-839	270	4	optofluidic	optofluidic	ADJ
admet-839	270	5	single	single	ADJ
admet-839	270	6	-	-	PUNCT
admet-839	270	7	particle	particle	NOUN
admet-839	270	8	method	method	NOUN
admet-839	270	9	for	for	ADP
admet-839	270	10	rapid	rapid	ADJ
admet-839	270	11	microscale	microscale	ADJ
admet-839	270	12	equilibrium	equilibrium	NOUN
admet-839	270	13	solubility	solubility	NOUN
admet-839	270	14	screening	screening	NOUN
admet-839	270	15	of	of	ADP
admet-839	270	16	biologically	biologically	ADV
admet-839	270	17	active	active	ADJ
admet-839	270	18	substances	substance	NOUN
admet-839	270	19	.	.	PUNCT
admet-839	271	1	anal	anal	ADJ
admet-839	271	2	.	.	PUNCT
admet-839	271	3	chem	chem	PROPN
admet-839	271	4	.	.	PUNCT
admet-839	272	1	87	87	NUM
admet-839	272	2	(	(	PUNCT
admet-839	272	3	2015	2015	NUM
admet-839	272	4	)	)	PUNCT
admet-839	272	5	5041–5045	5041–5045	NUM
admet-839	272	6	.	.	PUNCT
admet-839	273	1	[	[	X
admet-839	273	2	18	18	NUM
admet-839	273	3	]	]	X
admet-839	273	4	j.	j.	PROPN
admet-839	273	5	štukelj	štukelj	PROPN
admet-839	273	6	,	,	PUNCT
admet-839	273	7	s.	s.	PROPN
admet-839	273	8	svanbäck	svanbäck	PROPN
admet-839	273	9	,	,	PUNCT
admet-839	273	10	m.	m.	NOUN
admet-839	273	11	agopov	agopov	PROPN
admet-839	273	12	,	,	PUNCT
admet-839	273	13	k.	k.	PROPN
admet-839	273	14	löbmann	löbmann	PROPN
admet-839	273	15	,	,	PUNCT
admet-839	273	16	c.j	c.j	PROPN
admet-839	273	17	.	.	PROPN
admet-839	273	18	strachan	strachan	PROPN
admet-839	273	19	,	,	PUNCT
admet-839	273	20	t.	t.	PROPN
admet-839	273	21	rades	rades	PROPN
admet-839	273	22	,	,	PUNCT
admet-839	273	23	j.	j.	PROPN
admet-839	273	24	yliruusi	yliruusi	PROPN
admet-839	273	25	.	.	PUNCT
admet-839	274	1	direct	direct	ADJ
admet-839	274	2	measurement	measurement	NOUN
admet-839	274	3	of	of	ADP
admet-839	274	4	amorphous	amorphous	ADJ
admet-839	274	5	solubility	solubility	NOUN
admet-839	274	6	.	.	PUNCT
admet-839	275	1	anal	anal	PROPN
admet-839	275	2	.	.	PUNCT
admet-839	275	3	chem	chem	PROPN
admet-839	275	4	.	.	PUNCT
admet-839	276	1	91	91	NUM
admet-839	276	2	(	(	PUNCT
admet-839	276	3	2019	2019	NUM
admet-839	276	4	)	)	PUNCT
admet-839	276	5	7411–7417	7411–7417	NUM
admet-839	276	6	.	.	PUNCT
admet-839	277	1	[	[	X
admet-839	277	2	19	19	NUM
admet-839	277	3	]	]	PUNCT
admet-839	277	4	m.	m.	NOUN
admet-839	277	5	savolainen	savolainen	PROPN
admet-839	277	6	,	,	PUNCT
admet-839	277	7	a.	a.	PROPN
admet-839	277	8	heinz	heinz	PROPN
admet-839	277	9	,	,	PUNCT
admet-839	277	10	c.	c.	PROPN
admet-839	277	11	strachan	strachan	PROPN
admet-839	277	12	,	,	PUNCT
admet-839	277	13	k.	k.	PROPN
admet-839	277	14	c.	c.	PROPN
admet-839	277	15	gordon	gordon	PROPN
admet-839	277	16	,	,	PUNCT
admet-839	277	17	j.	j.	PROPN
admet-839	277	18	yliruusi	yliruusi	PROPN
admet-839	277	19	,	,	PUNCT
admet-839	277	20	t.	t.	PROPN
admet-839	277	21	rades	rades	PROPN
admet-839	277	22	,	,	PUNCT
admet-839	277	23	n.	n.	NOUN
admet-839	277	24	sandler	sandler	PROPN
admet-839	277	25	.	.	PUNCT
admet-839	278	1	screening	screen	VERB
admet-839	278	2	for	for	ADP
admet-839	278	3	differences	difference	NOUN
admet-839	278	4	in	in	ADP
admet-839	278	5	the	the	DET
admet-839	278	6	amorphous	amorphous	ADJ
admet-839	278	7	state	state	NOUN
admet-839	278	8	of	of	ADP
admet-839	278	9	indomethacin	indomethacin	NOUN
admet-839	278	10	using	use	VERB
admet-839	278	11	multivariate	multivariate	NOUN
admet-839	278	12	visualization	visualization	NOUN
admet-839	278	13	.	.	PUNCT
admet-839	279	1	eur	eur	PROPN
admet-839	279	2	.	.	PUNCT
admet-839	280	1	j.	j.	PROPN
admet-839	280	2	pharm	pharm	PROPN
admet-839	280	3	.	.	PUNCT
admet-839	281	1	sci	sci	PROPN
admet-839	281	2	.	.	PROPN
admet-839	281	3	,	,	PUNCT
admet-839	281	4	vol	vol	NOUN
admet-839	281	5	.	.	PROPN
admet-839	281	6	30	30	NUM
admet-839	281	7	(	(	PUNCT
admet-839	281	8	2007	2007	NUM
admet-839	281	9	)	)	PUNCT
admet-839	281	10	113–123	113–123	NUM
admet-839	281	11	.	.	PUNCT
admet-839	282	1	[	[	X
admet-839	282	2	20	20	NUM
admet-839	282	3	]	]	X
admet-839	282	4	s.a	s.a	PROPN
admet-839	282	5	.	.	PROPN
admet-839	282	6	surwase	surwase	PROPN
admet-839	282	7	,	,	PUNCT
admet-839	282	8	j.p	j.p	PROPN
admet-839	282	9	.	.	PROPN
admet-839	282	10	boetker	boetker	PROPN
admet-839	282	11	,	,	PUNCT
admet-839	282	12	d.	d.	PROPN
admet-839	282	13	saville	saville	PROPN
admet-839	282	14	,	,	PUNCT
admet-839	282	15	b.j	b.j	PROPN
admet-839	282	16	.	.	PROPN
admet-839	282	17	boyd	boyd	PROPN
admet-839	282	18	,	,	PUNCT
admet-839	282	19	k.c	k.c	PROPN
admet-839	282	20	.	.	PROPN
admet-839	282	21	gordon	gordon	PROPN
admet-839	282	22	,	,	PUNCT
admet-839	282	23	l.	l.	PROPN
admet-839	282	24	peltonen	peltonen	PROPN
admet-839	282	25	,	,	PUNCT
admet-839	282	26	c.j	c.j	PROPN
admet-839	282	27	.	.	PROPN
admet-839	282	28	strachan	strachan	PROPN
admet-839	282	29	.	.	PROPN
admet-839	282	30	indomethacin	indomethacin	PROPN
admet-839	282	31	:	:	PUNCT
admet-839	282	32	new	new	ADJ
admet-839	282	33	polymorphs	polymorph	NOUN
admet-839	282	34	of	of	ADP
admet-839	282	35	an	an	DET
admet-839	282	36	old	old	ADJ
admet-839	282	37	drug	drug	NOUN
admet-839	282	38	.	.	PUNCT
admet-839	283	1	mol	mol	PROPN
admet-839	283	2	.	.	PUNCT
admet-839	283	3	pharm	pharm	PROPN
admet-839	283	4	.	.	PUNCT
admet-839	284	1	10	10	NUM
admet-839	284	2	(	(	PUNCT
admet-839	284	3	2013	2013	NUM
admet-839	284	4	)	)	PUNCT
admet-839	284	5	4472–4480	4472–4480	NOUN
admet-839	284	6	.	.	PUNCT
admet-839	285	1	[	[	X
admet-839	285	2	21	21	NUM
admet-839	285	3	]	]	X
admet-839	285	4	j.e	j.e	PROPN
admet-839	285	5	.	.	PROPN
admet-839	285	6	patterson	patterson	PROPN
admet-839	285	7	,	,	PUNCT
admet-839	285	8	m.b	m.b	PROPN
admet-839	285	9	.	.	PROPN
admet-839	285	10	james	james	PROPN
admet-839	285	11	,	,	PUNCT
admet-839	285	12	a.h	a.h	PROPN
admet-839	285	13	.	.	PROPN
admet-839	285	14	forster	forster	PROPN
admet-839	285	15	,	,	PUNCT
admet-839	285	16	r.w	r.w	PROPN
admet-839	285	17	.	.	PROPN
admet-839	285	18	lancaster	lancaster	PROPN
admet-839	285	19	,	,	PUNCT
admet-839	285	20	j.m	j.m	PROPN
admet-839	285	21	.	.	PROPN
admet-839	285	22	butler	butler	PROPN
admet-839	285	23	,	,	PUNCT
admet-839	285	24	t.	t.	PROPN
admet-839	285	25	rades	rade	NOUN
admet-839	285	26	.	.	PUNCT
admet-839	286	1	the	the	DET
admet-839	286	2	influence	influence	NOUN
admet-839	286	3	of	of	ADP
admet-839	286	4	thermal	thermal	ADJ
admet-839	286	5	and	and	CCONJ
admet-839	286	6	mechanical	mechanical	ADJ
admet-839	286	7	preparative	preparative	ADJ
admet-839	286	8	techniques	technique	NOUN
admet-839	286	9	on	on	ADP
admet-839	286	10	the	the	DET
admet-839	286	11	amorphous	amorphous	ADJ
admet-839	286	12	state	state	NOUN
admet-839	286	13	of	of	ADP
admet-839	286	14	four	four	NUM
admet-839	286	15	poorly	poorly	ADV
admet-839	286	16	soluble	soluble	ADJ
admet-839	286	17	compounds	compound	NOUN
admet-839	286	18	.	.	PUNCT
admet-839	287	1	j.	j.	PROPN
admet-839	287	2	pharm	pharm	PROPN
admet-839	287	3	.	.	PUNCT
admet-839	288	1	sci	sci	PROPN
admet-839	288	2	.	.	PROPN
admet-839	289	1	94	94	NUM
admet-839	289	2	(	(	PUNCT
admet-839	289	3	2005	2005	NUM
admet-839	289	4	)	)	PUNCT
admet-839	289	5	1998–2012	1998–2012	NUM
admet-839	289	6	.	.	PUNCT
admet-839	290	1	[	[	X
admet-839	290	2	22	22	NUM
admet-839	290	3	]	]	PUNCT
admet-839	290	4	j.	j.	PROPN
admet-839	290	5	štukelj	štukelj	PROPN
admet-839	290	6	,	,	PUNCT
admet-839	290	7	s.	s.	PROPN
admet-839	290	8	svanbäck	svanbäck	PROPN
admet-839	290	9	,	,	PUNCT
admet-839	290	10	j.	j.	PROPN
admet-839	290	11	kristl	kristl	PROPN
admet-839	290	12	,	,	PUNCT
admet-839	290	13	c.j	c.j	PROPN
admet-839	290	14	.	.	PROPN
admet-839	290	15	strachan	strachan	PROPN
admet-839	290	16	,	,	PUNCT
admet-839	290	17	j.	j.	PROPN
admet-839	290	18	yliruusi	yliruusi	PROPN
admet-839	290	19	.	.	PUNCT
admet-839	291	1	image	image	NOUN
admet-839	291	2	-	-	PUNCT
admet-839	291	3	based	base	VERB
admet-839	291	4	investigation	investigation	NOUN
admet-839	291	5	:	:	PUNCT
admet-839	291	6	biorelevant	biorelevant	NOUN
admet-839	291	7	solubility	solubility	NOUN
admet-839	291	8	of	of	ADP
admet-839	291	9	α	α	PROPN
admet-839	291	10	and	and	CCONJ
admet-839	291	11	γ	γ	PROPN
admet-839	291	12	indomethacin	indomethacin	PROPN
admet-839	291	13	.	.	PUNCT
admet-839	292	1	anal	anal	PROPN
admet-839	292	2	.	.	PUNCT
admet-839	292	3	chem	chem	PROPN
admet-839	292	4	.	.	PUNCT
admet-839	293	1	91	91	NUM
admet-839	293	2	(	(	PUNCT
admet-839	293	3	2019	2019	NUM
admet-839	293	4	)	)	PUNCT
admet-839	293	5	3997–4003	3997–4003	NUM
admet-839	293	6	.	.	PUNCT
admet-839	294	1	[	[	X
admet-839	294	2	23	23	NUM
admet-839	294	3	]	]	X
admet-839	294	4	s.	s.	PROPN
admet-839	294	5	svanbäck	svanbäck	PROPN
admet-839	294	6	.	.	PUNCT
admet-839	295	1	toward	toward	ADP
admet-839	295	2	accurate	accurate	ADJ
admet-839	295	3	high	high	ADJ
admet-839	295	4	-	-	PUNCT
admet-839	295	5	throughput	throughput	NOUN
admet-839	295	6	physicochemical	physicochemical	ADJ
admet-839	295	7	profiling	profiling	NOUN
admet-839	295	8	using	use	VERB
admet-839	295	9	image	image	NOUN
admet-839	295	10	-	-	PUNCT
admet-839	295	11	based	base	VERB
admet-839	295	12	singleparticle	singleparticle	NOUN
admet-839	295	13	analysis	analysis	NOUN
admet-839	295	14	.	.	PUNCT
admet-839	296	1	ph.d	ph.d	PROPN
admet-839	296	2	.	.	PUNCT
admet-839	296	3	dissertation	dissertation	NOUN
admet-839	296	4	.	.	PUNCT
admet-839	297	1	university	university	NOUN
admet-839	297	2	of	of	ADP
admet-839	297	3	helsinki	helsinki	PROPN
admet-839	297	4	,	,	PUNCT
admet-839	297	5	finland	finland	PROPN
admet-839	297	6	,	,	PUNCT
admet-839	297	7	2016	2016	NUM
admet-839	297	8	.	.	PUNCT
admet-839	298	1	[	[	X
admet-839	298	2	24	24	NUM
admet-839	298	3	]	]	PUNCT
admet-839	298	4	p.	p.	NOUN
admet-839	298	5	karmwar	karmwar	PROPN
admet-839	298	6	,	,	PUNCT
admet-839	298	7	k.	k.	PROPN
admet-839	298	8	graeser	graeser	PROPN
admet-839	298	9	,	,	PUNCT
admet-839	298	10	k.c	k.c	PROPN
admet-839	298	11	.	.	PROPN
admet-839	298	12	gordon	gordon	PROPN
admet-839	298	13	,	,	PUNCT
admet-839	298	14	c.j	c.j	PROPN
admet-839	298	15	.	.	PROPN
admet-839	298	16	strachan	strachan	PROPN
admet-839	298	17	.	.	PUNCT
admet-839	298	18	investigation	investigation	NOUN
admet-839	298	19	of	of	ADP
admet-839	298	20	properties	property	NOUN
admet-839	298	21	and	and	CCONJ
admet-839	298	22	recrystallisation	recrystallisation	NOUN
admet-839	298	23	behaviour	behaviour	NOUN
admet-839	298	24	of	of	ADP
admet-839	298	25	amorphous	amorphous	ADJ
admet-839	298	26	indomethacin	indomethacin	NOUN
admet-839	298	27	samples	sample	NOUN
admet-839	298	28	prepared	prepare	VERB
admet-839	298	29	by	by	ADP
admet-839	298	30	different	different	ADJ
admet-839	298	31	methods	method	NOUN
admet-839	298	32	.	.	PUNCT
admet-839	299	1	int	int	NOUN
admet-839	299	2	.	.	PUNCT
admet-839	300	1	j.	j.	PROPN
admet-839	300	2	pharm	pharm	PROPN
admet-839	300	3	.	.	PUNCT
admet-839	301	1	417	417	NUM
admet-839	301	2	(	(	PUNCT
admet-839	301	3	2011	2011	NUM
admet-839	301	4	)	)	PUNCT
admet-839	301	5	94–100	94–100	NUM
admet-839	301	6	.	.	PUNCT
admet-839	302	1	[	[	X
admet-839	302	2	25	25	NUM
admet-839	302	3	]	]	X
admet-839	302	4	w.l	w.l	PROPN
admet-839	302	5	.	.	PROPN
admet-839	302	6	jorgensen	jorgensen	PROPN
admet-839	302	7	,	,	PUNCT
admet-839	302	8	e.m	e.m	PROPN
admet-839	302	9	.	.	PROPN
admet-839	302	10	duffy	duffy	PROPN
admet-839	302	11	.	.	PROPN
admet-839	302	12	prediction	prediction	NOUN
admet-839	302	13	of	of	ADP
admet-839	302	14	drug	drug	NOUN
admet-839	302	15	solubility	solubility	NOUN
admet-839	302	16	from	from	ADP
admet-839	302	17	structure	structure	NOUN
admet-839	302	18	.	.	PUNCT
admet-839	303	1	adv	adv	PROPN
admet-839	303	2	.	.	PUNCT
admet-839	303	3	drug	drug	PROPN
admet-839	303	4	deliv	deliv	PROPN
admet-839	303	5	.	.	PUNCT
admet-839	304	1	rev	rev	PROPN
admet-839	304	2	.	.	PROPN
admet-839	304	3	54	54	NUM
admet-839	304	4	(	(	PUNCT
admet-839	304	5	2002	2002	NUM
admet-839	304	6	)	)	PUNCT
admet-839	305	1	355–366	355–366	NUM
admet-839	305	2	.	.	PUNCT
admet-839	306	1	[	[	X
admet-839	306	2	26	26	NUM
admet-839	306	3	]	]	X
admet-839	306	4	d.	d.	PROPN
admet-839	306	5	novakovic	novakovic	PROPN
admet-839	306	6	,	,	PUNCT
admet-839	306	7	j.	j.	PROPN
admet-839	306	8	saarinen	saarinen	PROPN
admet-839	306	9	,	,	PUNCT
admet-839	306	10	t.	t.	PROPN
admet-839	306	11	rojalin	rojalin	PROPN
admet-839	306	12	,	,	PUNCT
admet-839	306	13	o.	o.	PROPN
admet-839	306	14	antikainen	antikainen	PROPN
admet-839	306	15	,	,	PUNCT
admet-839	306	16	s.	s.	PROPN
admet-839	306	17	j.	j.	PROPN
admet-839	306	18	fraser	fraser	PROPN
admet-839	306	19	-	-	PUNCT
admet-839	306	20	miller	miller	PROPN
admet-839	306	21	,	,	PUNCT
admet-839	306	22	t.	t.	PROPN
admet-839	306	23	laaksonen	laaksonen	PROPN
admet-839	306	24	,	,	PUNCT
admet-839	306	25	l.	l.	PROPN
admet-839	306	26	peltonen	peltonen	PROPN
admet-839	306	27	,	,	PUNCT
admet-839	306	28	a.	a.	NOUN
admet-839	306	29	isomäki	isomäki	NOUN
admet-839	306	30	,	,	PUNCT
admet-839	306	31	c.	c.	PROPN
admet-839	306	32	j.	j.	PROPN
admet-839	306	33	strachan	strachan	PROPN
admet-839	306	34	.	.	PUNCT
admet-839	306	35	multimodal	multimodal	ADJ
admet-839	306	36	non	non	ADJ
admet-839	306	37	-	-	ADJ
admet-839	306	38	linear	linear	ADJ
admet-839	306	39	optical	optical	ADJ
admet-839	306	40	imaging	imaging	NOUN
admet-839	306	41	for	for	ADP
admet-839	306	42	sensitive	sensitive	ADJ
admet-839	306	43	detection	detection	NOUN
admet-839	306	44	of	of	ADP
admet-839	306	45	multiple	multiple	ADJ
admet-839	306	46	pharmaceutical	pharmaceutical	ADJ
admet-839	306	47	solid	solid	ADJ
admet-839	306	48	-	-	PUNCT
admet-839	306	49	state	state	NOUN
admet-839	306	50	forms	form	NOUN
admet-839	306	51	and	and	CCONJ
admet-839	306	52	surface	surface	NOUN
admet-839	306	53	transformations	transformation	NOUN
admet-839	306	54	.	.	PUNCT
admet-839	307	1	anal	anal	ADJ
admet-839	307	2	.	.	PUNCT
admet-839	307	3	chem	chem	PROPN
admet-839	307	4	.	.	PUNCT
admet-839	308	1	89	89	NUM
admet-839	308	2	(	(	PUNCT
admet-839	308	3	2017	2017	NUM
admet-839	308	4	)	)	PUNCT
admet-839	308	5	11460–11467	11460–11467	NUM
admet-839	308	6	.	.	PUNCT
admet-839	309	1	©	©	PROPN
admet-839	309	2	2020	2020	NUM
admet-839	309	3	by	by	ADP
admet-839	309	4	the	the	DET
admet-839	309	5	authors	author	NOUN
admet-839	309	6	;	;	PUNCT
admet-839	309	7	licensee	licensee	PROPN
admet-839	309	8	iapc	iapc	PROPN
admet-839	309	9	,	,	PUNCT
admet-839	309	10	zagreb	zagreb	PROPN
admet-839	309	11	,	,	PUNCT
admet-839	309	12	croatia	croatia	PROPN
admet-839	309	13	.	.	PUNCT
admet-839	310	1	this	this	DET
admet-839	310	2	article	article	NOUN
admet-839	310	3	is	be	AUX
admet-839	310	4	an	an	DET
admet-839	310	5	open	open	ADJ
admet-839	310	6	-	-	PUNCT
admet-839	310	7	access	access	NOUN
admet-839	310	8	article	article	NOUN
admet-839	310	9	distributed	distribute	VERB
admet-839	310	10	under	under	ADP
admet-839	310	11	the	the	DET
admet-839	310	12	terms	term	NOUN
admet-839	310	13	and	and	CCONJ
admet-839	310	14	conditions	condition	NOUN
admet-839	310	15	of	of	ADP
admet-839	310	16	the	the	DET
admet-839	310	17	creative	creative	ADJ
admet-839	310	18	commons	common	NOUN
admet-839	310	19	attribution	attribution	NOUN
admet-839	310	20	license	license	NOUN
admet-839	310	21	(	(	PUNCT
admet-839	310	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-839	310	23	)	)	PUNCT
admet-839	310	24	http://dx.doi.org/10.5599/admet.839	http://dx.doi.org/10.5599/admet.839	VERB
admet-839	310	25	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN