id	sid	tid	token	lemma	pos
admet-843	1	1	solubility	solubility	NOUN
admet-843	1	2	and	and	CCONJ
admet-843	1	3	admet	admet	PROPN
admet-843	1	4	profiles	profile	NOUN
admet-843	1	5	of	of	ADP
admet-843	1	6	short	short	ADJ
admet-843	1	7	oligomers	oligomer	NOUN
admet-843	1	8	of	of	ADP
admet-843	1	9	lactic	lactic	ADJ
admet-843	1	10	acid	acid	NOUN
admet-843	1	11	doi	doi	NOUN
admet-843	1	12	:	:	PUNCT
admet-843	1	13	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	NOUN
admet-843	1	14	425	425	NUM
admet-843	1	15	admet	admet	PROPN
admet-843	1	16	&	&	CCONJ
admet-843	1	17	dmpk	dmpk	PROPN
admet-843	1	18	8(4	8(4	NOUN
admet-843	1	19	)	)	PUNCT
admet-843	1	20	(	(	PUNCT
admet-843	1	21	2020	2020	NUM
admet-843	1	22	)	)	PUNCT
admet-843	1	23	425	425	NUM
admet-843	1	24	-	-	SYM
admet-843	1	25	436	436	NUM
admet-843	1	26	;	;	PUNCT
admet-843	1	27	doi	doi	NOUN
admet-843	1	28	:	:	PUNCT
admet-843	1	29	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	ADP
admet-843	1	30	open	open	ADJ
admet-843	1	31	access	access	NOUN
admet-843	1	32	:	:	PUNCT
admet-843	1	33	issn	issn	PROPN
admet-843	1	34	:	:	PUNCT
admet-843	1	35	1848	1848	NUM
admet-843	1	36	-	-	SYM
admet-843	1	37	7718	7718	NUM
admet-843	1	38	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-843	1	39	original	original	ADJ
admet-843	1	40	scientific	scientific	ADJ
admet-843	1	41	paper	paper	NOUN
admet-843	1	42	solubility	solubility	NOUN
admet-843	1	43	and	and	CCONJ
admet-843	1	44	admet	admet	PROPN
admet-843	1	45	profiles	profile	NOUN
admet-843	1	46	of	of	ADP
admet-843	1	47	short	short	ADJ
admet-843	1	48	oligomers	oligomer	NOUN
admet-843	1	49	of	of	ADP
admet-843	1	50	lactic	lactic	ADJ
admet-843	1	51	acid	acid	NOUN
admet-843	1	52	daniela	daniela	NOUN
admet-843	1	53	dascălu1	dascălu1	PROPN
admet-843	1	54	#	#	PROPN
admet-843	1	55	,	,	PUNCT
admet-843	1	56	diana	diana	PROPN
admet-843	1	57	larisa	larisa	PROPN
admet-843	1	58	roman1	roman1	PROPN
admet-843	1	59	#	#	PROPN
admet-843	1	60	,	,	PUNCT
admet-843	1	61	madalina	madalina	PROPN
admet-843	1	62	filip1	filip1	PROPN
admet-843	1	63	,	,	PUNCT
admet-843	1	64	alecu	alecu	PROPN
admet-843	1	65	ciorsac2	ciorsac2	PROPN
admet-843	1	66	,	,	PUNCT
admet-843	1	67	vasile	vasile	PROPN
admet-843	1	68	ostafe1	ostafe1	PROPN
admet-843	1	69	,	,	PUNCT
admet-843	1	70	adriana	adriana	PROPN
admet-843	1	71	isvoran1	isvoran1	PROPN
admet-843	1	72	*	*	SYM
admet-843	1	73	1	1	NUM
admet-843	1	74	department	department	NOUN
admet-843	1	75	of	of	ADP
admet-843	1	76	biology	biology	NOUN
admet-843	1	77	-	-	PUNCT
admet-843	1	78	chemistry	chemistry	NOUN
admet-843	1	79	and	and	CCONJ
admet-843	1	80	advanced	advanced	ADJ
admet-843	1	81	environmental	environmental	ADJ
admet-843	1	82	research	research	NOUN
admet-843	1	83	laboratories	laboratory	NOUN
admet-843	1	84	,	,	PUNCT
admet-843	1	85	west	west	PROPN
admet-843	1	86	university	university	PROPN
admet-843	1	87	of	of	ADP
admet-843	1	88	timișoara	timișoara	PROPN
admet-843	1	89	,	,	PUNCT
admet-843	1	90	timișoara	timișoara	PROPN
admet-843	1	91	,	,	PUNCT
admet-843	1	92	romania	romania	PROPN
admet-843	1	93	2	2	NUM
admet-843	1	94	department	department	NOUN
admet-843	1	95	of	of	ADP
admet-843	1	96	physical	physical	ADJ
admet-843	1	97	education	education	NOUN
admet-843	1	98	and	and	CCONJ
admet-843	1	99	sport	sport	NOUN
admet-843	1	100	,	,	PUNCT
admet-843	1	101	university	university	NOUN
admet-843	1	102	politehnica	politehnica	NOUN
admet-843	1	103	timișoara	timișoara	PROPN
admet-843	1	104	,	,	PUNCT
admet-843	1	105	timișoara	timișoara	PROPN
admet-843	1	106	,	,	PUNCT
admet-843	1	107	romania	romania	PROPN
admet-843	1	108	;	;	PUNCT
admet-843	1	109	*	*	PUNCT
admet-843	1	110	corresponding	correspond	VERB
admet-843	1	111	author	author	NOUN
admet-843	1	112	:	:	PUNCT
admet-843	1	113	e	e	NOUN
admet-843	1	114	-	-	NOUN
admet-843	1	115	mail	mail	NOUN
admet-843	1	116	:	:	PUNCT
admet-843	1	117	adriana.isvoran@e-uvt.ro	adriana.isvoran@e-uvt.ro	NOUN
admet-843	1	118	;	;	PUNCT
admet-843	1	119	tel	tel	PROPN
admet-843	1	120	.	.	PROPN
admet-843	1	121	:	:	PUNCT
admet-843	2	1	+40	+40	VERB
admet-843	2	2	-	-	SYM
admet-843	2	3	256	256	NUM
admet-843	2	4	-	-	NUM
admet-843	2	5	592	592	NUM
admet-843	2	6	-	-	NUM
admet-843	2	7	634	634	NUM
admet-843	2	8	;	;	PUNCT
admet-843	2	9	fax	fax	NOUN
admet-843	2	10	:	:	PUNCT
admet-843	2	11	+40	+40	ADJ
admet-843	2	12	-	-	SYM
admet-843	2	13	256	256	NUM
admet-843	2	14	-	-	NUM
admet-843	2	15	592	592	NUM
admet-843	2	16	-	-	NUM
admet-843	2	17	620	620	NUM
admet-843	2	18	#	#	NOUN
admet-843	2	19	the	the	DET
admet-843	2	20	two	two	NUM
admet-843	2	21	authors	author	NOUN
admet-843	2	22	have	have	VERB
admet-843	2	23	an	an	DET
admet-843	2	24	equal	equal	ADJ
admet-843	2	25	contribution	contribution	NOUN
admet-843	2	26	to	to	ADP
admet-843	2	27	this	this	DET
admet-843	2	28	study	study	NOUN
admet-843	2	29	.	.	PUNCT
admet-843	3	1	received	receive	VERB
admet-843	3	2	:	:	PUNCT
admet-843	3	3	may	may	AUX
admet-843	3	4	01	01	NUM
admet-843	3	5	,	,	PUNCT
admet-843	3	6	2020	2020	NUM
admet-843	3	7	;	;	PUNCT
admet-843	3	8	revised	revise	VERB
admet-843	3	9	:	:	PUNCT
admet-843	3	10	june	june	PROPN
admet-843	3	11	21	21	NUM
admet-843	3	12	,	,	PUNCT
admet-843	3	13	2020	2020	NUM
admet-843	3	14	;	;	PUNCT
admet-843	3	15	published	publish	VERB
admet-843	3	16	:	:	PUNCT
admet-843	3	17	june	june	PROPN
admet-843	3	18	28	28	NUM
admet-843	3	19	,	,	PUNCT
admet-843	3	20	2020	2020	NUM
admet-843	3	21	abstract	abstract	ADJ
admet-843	3	22	polylactic	polylactic	ADJ
admet-843	3	23	acid	acid	NOUN
admet-843	3	24	(	(	PUNCT
admet-843	3	25	pla	pla	NOUN
admet-843	3	26	)	)	PUNCT
admet-843	3	27	is	be	AUX
admet-843	3	28	a	a	DET
admet-843	3	29	polymer	polymer	NOUN
admet-843	3	30	with	with	ADP
admet-843	3	31	an	an	DET
admet-843	3	32	increased	increase	VERB
admet-843	3	33	potential	potential	NOUN
admet-843	3	34	to	to	PART
admet-843	3	35	be	be	AUX
admet-843	3	36	used	use	VERB
admet-843	3	37	in	in	ADP
admet-843	3	38	different	different	ADJ
admet-843	3	39	medical	medical	ADJ
admet-843	3	40	applications	application	NOUN
admet-843	3	41	,	,	PUNCT
admet-843	3	42	including	include	VERB
admet-843	3	43	tissue	tissue	NOUN
admet-843	3	44	engineering	engineering	NOUN
admet-843	3	45	and	and	CCONJ
admet-843	3	46	drug	drug	NOUN
admet-843	3	47	-	-	PUNCT
admet-843	3	48	carries	carry	VERB
admet-843	3	49	.	.	PUNCT
admet-843	4	1	the	the	DET
admet-843	4	2	use	use	NOUN
admet-843	4	3	of	of	ADP
admet-843	4	4	pla	pla	NOUN
admet-843	4	5	in	in	ADP
admet-843	4	6	medical	medical	ADJ
admet-843	4	7	applications	application	NOUN
admet-843	4	8	implies	imply	VERB
admet-843	4	9	the	the	DET
admet-843	4	10	evaluation	evaluation	NOUN
admet-843	4	11	of	of	ADP
admet-843	4	12	the	the	DET
admet-843	4	13	human	human	ADJ
admet-843	4	14	organism	organism	NOUN
admet-843	4	15	's	's	PART
admet-843	4	16	response	response	NOUN
admet-843	4	17	to	to	ADP
admet-843	4	18	the	the	DET
admet-843	4	19	polymer	polymer	NOUN
admet-843	4	20	inserting	inserting	NOUN
admet-843	4	21	and	and	CCONJ
admet-843	4	22	to	to	ADP
admet-843	4	23	its	its	PRON
admet-843	4	24	degradation	degradation	NOUN
admet-843	4	25	products	product	NOUN
admet-843	4	26	.	.	PUNCT
admet-843	5	1	consequently	consequently	ADV
admet-843	5	2	,	,	PUNCT
admet-843	5	3	within	within	ADP
admet-843	5	4	this	this	DET
admet-843	5	5	study	study	NOUN
admet-843	5	6	,	,	PUNCT
admet-843	5	7	we	we	PRON
admet-843	5	8	have	have	AUX
admet-843	5	9	investigated	investigate	VERB
admet-843	5	10	the	the	DET
admet-843	5	11	solubility	solubility	NOUN
admet-843	5	12	and	and	CCONJ
admet-843	5	13	admet	admet	PROPN
admet-843	5	14	profiles	profile	NOUN
admet-843	5	15	of	of	ADP
admet-843	5	16	the	the	DET
admet-843	5	17	short	short	ADJ
admet-843	5	18	oligomers	oligomer	NOUN
admet-843	5	19	(	(	PUNCT
admet-843	5	20	having	have	VERB
admet-843	5	21	the	the	DET
admet-843	5	22	molecular	molecular	ADJ
admet-843	5	23	weight	weight	NOUN
admet-843	5	24	lower	low	ADJ
admet-843	5	25	than	than	ADP
admet-843	5	26	3000	3000	NUM
admet-843	5	27	da	da	NOUN
admet-843	5	28	)	)	PUNCT
admet-843	5	29	resulting	result	VERB
admet-843	5	30	in	in	ADP
admet-843	5	31	degradation	degradation	NOUN
admet-843	5	32	products	product	NOUN
admet-843	5	33	of	of	ADP
admet-843	5	34	pla	pla	NOUN
admet-843	5	35	.	.	PUNCT
admet-843	6	1	there	there	PRON
admet-843	6	2	is	be	VERB
admet-843	6	3	a	a	DET
admet-843	6	4	linear	linear	ADJ
admet-843	6	5	decrease	decrease	NOUN
admet-843	6	6	of	of	ADP
admet-843	6	7	the	the	DET
admet-843	6	8	molar	molar	ADJ
admet-843	6	9	solubility	solubility	NOUN
admet-843	6	10	of	of	ADP
admet-843	6	11	investigated	investigate	VERB
admet-843	6	12	oligomers	oligomer	NOUN
admet-843	6	13	with	with	ADP
admet-843	6	14	molecular	molecular	ADJ
admet-843	6	15	weight	weight	NOUN
admet-843	6	16	.	.	PUNCT
admet-843	7	1	the	the	DET
admet-843	7	2	results	result	NOUN
admet-843	7	3	that	that	PRON
admet-843	7	4	are	be	AUX
admet-843	7	5	obtained	obtain	VERB
admet-843	7	6	also	also	ADV
admet-843	7	7	reveal	reveal	VERB
admet-843	7	8	that	that	SCONJ
admet-843	7	9	short	short	ADJ
admet-843	7	10	oligomers	oligomer	NOUN
admet-843	7	11	of	of	ADP
admet-843	7	12	pla	pla	PROPN
admet-843	7	13	have	have	AUX
admet-843	7	14	promising	promise	VERB
admet-843	7	15	pharmacological	pharmacological	ADJ
admet-843	7	16	profiles	profile	NOUN
admet-843	7	17	and	and	CCONJ
admet-843	7	18	limited	limited	ADJ
admet-843	7	19	toxicological	toxicological	ADJ
admet-843	7	20	effects	effect	NOUN
admet-843	7	21	on	on	ADP
admet-843	7	22	humans	human	NOUN
admet-843	7	23	.	.	PUNCT
admet-843	8	1	these	these	DET
admet-843	8	2	oligomers	oligomer	NOUN
admet-843	8	3	are	be	AUX
admet-843	8	4	predicted	predict	VERB
admet-843	8	5	as	as	ADP
admet-843	8	6	potential	potential	ADJ
admet-843	8	7	inhibitors	inhibitor	NOUN
admet-843	8	8	of	of	ADP
admet-843	8	9	the	the	DET
admet-843	8	10	organic	organic	ADJ
admet-843	8	11	anion	anion	NOUN
admet-843	8	12	transporting	transport	VERB
admet-843	8	13	peptides	peptide	NOUN
admet-843	8	14	oatp1b1	oatp1b1	NOUN
admet-843	8	15	and	and	CCONJ
admet-843	8	16	oatp1b3	oatp1b3	NUM
admet-843	8	17	,	,	PUNCT
admet-843	8	18	they	they	PRON
admet-843	8	19	present	present	VERB
admet-843	8	20	minor	minor	ADJ
admet-843	8	21	probability	probability	NOUN
admet-843	8	22	to	to	PART
admet-843	8	23	affect	affect	VERB
admet-843	8	24	the	the	DET
admet-843	8	25	androgen	androgen	NOUN
admet-843	8	26	and	and	CCONJ
admet-843	8	27	glucocorticoid	glucocorticoid	ADJ
admet-843	8	28	receptors	receptor	NOUN
admet-843	8	29	,	,	PUNCT
admet-843	8	30	have	have	VERB
admet-843	8	31	a	a	DET
admet-843	8	32	weak	weak	ADJ
admet-843	8	33	potential	potential	NOUN
admet-843	8	34	of	of	ADP
admet-843	8	35	hepatotoxicity	hepatotoxicity	NOUN
admet-843	8	36	,	,	PUNCT
admet-843	8	37	and	and	CCONJ
admet-843	8	38	may	may	AUX
admet-843	8	39	produce	produce	VERB
admet-843	8	40	eye	eye	NOUN
admet-843	8	41	injuries	injury	NOUN
admet-843	8	42	.	.	PUNCT
admet-843	9	1	these	these	DET
admet-843	9	2	outcomes	outcome	NOUN
admet-843	9	3	may	may	AUX
admet-843	9	4	be	be	AUX
admet-843	9	5	used	use	VERB
admet-843	9	6	to	to	PART
admet-843	9	7	guide	guide	VERB
admet-843	9	8	or	or	CCONJ
admet-843	9	9	to	to	PART
admet-843	9	10	supplement	supplement	VERB
admet-843	9	11	in	in	ADP
admet-843	9	12	vitro	vitro	X
admet-843	9	13	and/or	and/or	CCONJ
admet-843	9	14	in	in	ADP
admet-843	9	15	vivo	vivo	ADJ
admet-843	9	16	toxicity	toxicity	NOUN
admet-843	9	17	tests	test	NOUN
admet-843	9	18	such	such	ADJ
admet-843	9	19	as	as	ADP
admet-843	9	20	to	to	PART
admet-843	9	21	enhance	enhance	VERB
admet-843	9	22	the	the	DET
admet-843	9	23	biodegradation	biodegradation	NOUN
admet-843	9	24	properties	property	NOUN
admet-843	9	25	of	of	ADP
admet-843	9	26	the	the	DET
admet-843	9	27	biopolymer	biopolymer	NOUN
admet-843	9	28	.	.	PUNCT
admet-843	10	1	©	©	PROPN
admet-843	10	2	2020	2020	NUM
admet-843	10	3	by	by	ADP
admet-843	10	4	the	the	DET
admet-843	10	5	authors	author	NOUN
admet-843	10	6	.	.	PUNCT
admet-843	11	1	this	this	DET
admet-843	11	2	article	article	NOUN
admet-843	11	3	is	be	AUX
admet-843	11	4	an	an	DET
admet-843	11	5	open	open	ADJ
admet-843	11	6	-	-	PUNCT
admet-843	11	7	access	access	NOUN
admet-843	11	8	article	article	NOUN
admet-843	11	9	distributed	distribute	VERB
admet-843	11	10	under	under	ADP
admet-843	11	11	the	the	DET
admet-843	11	12	terms	term	NOUN
admet-843	11	13	and	and	CCONJ
admet-843	11	14	conditions	condition	NOUN
admet-843	11	15	of	of	ADP
admet-843	11	16	the	the	DET
admet-843	11	17	creative	creative	ADJ
admet-843	11	18	commons	common	NOUN
admet-843	11	19	attribution	attribution	NOUN
admet-843	11	20	license	license	NOUN
admet-843	11	21	(	(	PUNCT
admet-843	11	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-843	11	23	)	)	PUNCT
admet-843	11	24	.	.	PUNCT
admet-843	12	1	keywords	keyword	VERB
admet-843	12	2	pharmacokinetics	pharmacokinetic	NOUN
admet-843	12	3	;	;	PUNCT
admet-843	12	4	toxicological	toxicological	ADJ
admet-843	12	5	endpoints	endpoint	NOUN
admet-843	12	6	;	;	PUNCT
admet-843	12	7	biodegradation	biodegradation	NOUN
admet-843	12	8	products	product	NOUN
admet-843	12	9	of	of	ADP
admet-843	12	10	pla	pla	NOUN
admet-843	12	11	introduction	introduction	NOUN
admet-843	12	12	for	for	ADP
admet-843	12	13	a	a	DET
admet-843	12	14	few	few	ADJ
admet-843	12	15	decades	decade	NOUN
admet-843	12	16	,	,	PUNCT
admet-843	12	17	biopolymers	biopolymer	NOUN
admet-843	12	18	are	be	AUX
admet-843	12	19	extensively	extensively	ADV
admet-843	12	20	in	in	ADP
admet-843	12	21	use	use	NOUN
admet-843	12	22	as	as	ADP
admet-843	12	23	food	food	NOUN
admet-843	12	24	additives	additive	NOUN
admet-843	12	25	,	,	PUNCT
admet-843	12	26	cosmetics	cosmetic	NOUN
admet-843	12	27	,	,	PUNCT
admet-843	12	28	medical	medical	ADJ
admet-843	12	29	materials	material	NOUN
admet-843	12	30	,	,	PUNCT
admet-843	12	31	water	water	NOUN
admet-843	12	32	treatment	treatment	NOUN
admet-843	12	33	chemicals	chemical	NOUN
admet-843	12	34	,	,	PUNCT
admet-843	12	35	packaging	packaging	NOUN
admet-843	12	36	,	,	PUNCT
admet-843	12	37	etc	etc	X
admet-843	12	38	.	.	X
admet-843	12	39	because	because	SCONJ
admet-843	12	40	of	of	ADP
admet-843	12	41	their	their	PRON
admet-843	12	42	intrinsic	intrinsic	ADJ
admet-843	12	43	properties	property	NOUN
admet-843	12	44	,	,	PUNCT
admet-843	12	45	especially	especially	ADV
admet-843	12	46	non	non	ADJ
admet-843	12	47	-	-	NOUN
admet-843	12	48	cytotoxicity	cytotoxicity	NOUN
admet-843	12	49	,	,	PUNCT
admet-843	12	50	biocompatibility	biocompatibility	NOUN
admet-843	12	51	and	and	CCONJ
admet-843	12	52	biodegradation	biodegradation	NOUN
admet-843	12	53	,	,	PUNCT
admet-843	12	54	biopolymers	biopolymer	NOUN
admet-843	12	55	are	be	AUX
admet-843	12	56	a	a	DET
admet-843	12	57	class	class	NOUN
admet-843	12	58	of	of	ADP
admet-843	12	59	materials	material	NOUN
admet-843	12	60	that	that	PRON
admet-843	12	61	provides	provide	VERB
admet-843	12	62	a	a	DET
admet-843	12	63	wide	wide	ADJ
admet-843	12	64	range	range	NOUN
admet-843	12	65	of	of	ADP
admet-843	12	66	applications	application	NOUN
admet-843	12	67	in	in	ADP
admet-843	12	68	medicine	medicine	NOUN
admet-843	12	69	[	[	X
admet-843	12	70	1	1	NUM
admet-843	12	71	]	]	PUNCT
admet-843	12	72	.	.	PUNCT
admet-843	13	1	they	they	PRON
admet-843	13	2	are	be	AUX
admet-843	13	3	considered	consider	VERB
admet-843	13	4	outstanding	outstanding	ADJ
admet-843	13	5	candidates	candidate	NOUN
admet-843	13	6	to	to	PART
admet-843	13	7	be	be	AUX
admet-843	13	8	used	use	VERB
admet-843	13	9	for	for	ADP
admet-843	13	10	the	the	DET
admet-843	13	11	preparation	preparation	NOUN
admet-843	13	12	of	of	ADP
admet-843	13	13	many	many	ADJ
admet-843	13	14	medical	medical	ADJ
admet-843	13	15	and	and	CCONJ
admet-843	13	16	body	body	NOUN
admet-843	13	17	implants	implant	NOUN
admet-843	13	18	and	and	CCONJ
admet-843	13	19	also	also	ADV
admet-843	13	20	as	as	ADP
admet-843	13	21	controlled	control	VERB
admet-843	13	22	drug	drug	NOUN
admet-843	13	23	delivery	delivery	NOUN
admet-843	13	24	systems	system	NOUN
admet-843	13	25	.	.	PUNCT
admet-843	14	1	polylactic	polylactic	ADJ
admet-843	14	2	acid	acid	NOUN
admet-843	14	3	(	(	PUNCT
admet-843	14	4	pla	pla	NOUN
admet-843	14	5	)	)	PUNCT
admet-843	14	6	,	,	PUNCT
admet-843	14	7	with	with	ADP
admet-843	14	8	the	the	DET
admet-843	14	9	chemical	chemical	NOUN
admet-843	14	10	formula	formula	NOUN
admet-843	14	11	(	(	PUNCT
admet-843	14	12	c3h4o2)n	c3h4o2)n	NOUN
admet-843	14	13	and	and	CCONJ
admet-843	14	14	illustrated	illustrate	VERB
admet-843	14	15	in	in	ADP
admet-843	14	16	figure	figure	NOUN
admet-843	14	17	1	1	NUM
admet-843	14	18	,	,	PUNCT
admet-843	14	19	is	be	AUX
admet-843	14	20	one	one	NUM
admet-843	14	21	of	of	ADP
admet-843	14	22	the	the	DET
admet-843	14	23	most	most	ADV
admet-843	14	24	commercially	commercially	ADV
admet-843	14	25	competitive	competitive	ADJ
admet-843	14	26	polymers	polymer	NOUN
admet-843	14	27	used	use	VERB
admet-843	14	28	for	for	ADP
admet-843	14	29	medical	medical	ADJ
admet-843	14	30	applications	application	NOUN
admet-843	14	31	acting	act	VERB
admet-843	14	32	as	as	ADP
admet-843	14	33	biologically	biologically	ADV
admet-843	14	34	inert	inert	ADJ
admet-843	14	35	supporting	support	VERB
admet-843	14	36	materials	material	NOUN
admet-843	14	37	as	as	ADP
admet-843	14	38	scaffolds	scaffold	NOUN
admet-843	14	39	or	or	CCONJ
admet-843	14	40	drug	drug	NOUN
admet-843	14	41	-	-	PUNCT
admet-843	14	42	carriers	carrier	NOUN
admet-843	14	43	[	[	X
admet-843	14	44	2,3	2,3	NUM
admet-843	14	45	]	]	PUNCT
admet-843	14	46	.	.	PUNCT
admet-843	15	1	pla	pla	PROPN
admet-843	15	2	is	be	AUX
admet-843	15	3	bio	bio	ADV
admet-843	15	4	absorbable	absorbable	PROPN
admet-843	15	5	being	be	AUX
admet-843	15	6	transformed	transform	VERB
admet-843	15	7	in	in	ADP
admet-843	15	8	the	the	DET
admet-843	15	9	human	human	ADJ
admet-843	15	10	organism	organism	NOUN
admet-843	15	11	by	by	ADP
admet-843	15	12	simple	simple	ADJ
admet-843	15	13	hydrolysis	hydrolysis	NOUN
admet-843	15	14	to	to	ADP
admet-843	15	15	products	product	NOUN
admet-843	15	16	that	that	PRON
admet-843	15	17	can	can	AUX
admet-843	15	18	be	be	AUX
admet-843	15	19	further	far	ADV
admet-843	15	20	metabolized	metabolize	VERB
admet-843	15	21	or	or	CCONJ
admet-843	15	22	excreted	excrete	VERB
admet-843	15	23	[	[	X
admet-843	15	24	4,5	4,5	NUM
admet-843	15	25	]	]	PUNCT
admet-843	15	26	.	.	PUNCT
admet-843	16	1	the	the	DET
admet-843	16	2	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	NOUN
admet-843	16	3	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	NOUN
admet-843	16	4	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-843	16	5	file:///y:/users/adriana/appdata/local/temp/adriana.isvoran@e-uvt.ro	file:///y:/users/adriana/appdata/local/temp/adriana.isvoran@e-uvt.ro	PROPN
admet-843	17	1	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-843	17	2	d.	d.	PROPN
admet-843	17	3	dascălu	dascălu	VERB
admet-843	17	4	et	et	PROPN
admet-843	17	5	al	al	PROPN
admet-843	17	6	.	.	PROPN
admet-843	17	7	admet	admet	PROPN
admet-843	17	8	&	&	CCONJ
admet-843	17	9	dmpk	dmpk	PROPN
admet-843	17	10	8(4	8(4	NOUN
admet-843	17	11	)	)	PUNCT
admet-843	17	12	(	(	PUNCT
admet-843	17	13	2020	2020	NUM
admet-843	17	14	)	)	PUNCT
admet-843	17	15	425	425	NUM
admet-843	17	16	-	-	SYM
admet-843	17	17	436	436	NUM
admet-843	17	18	426	426	NUM
admet-843	17	19	biomedical	biomedical	ADJ
admet-843	17	20	applications	application	NOUN
admet-843	17	21	of	of	ADP
admet-843	17	22	the	the	DET
admet-843	17	23	polylactic	polylactic	ADJ
admet-843	17	24	acid	acid	NOUN
admet-843	17	25	(	(	PUNCT
admet-843	17	26	pla	pla	NOUN
admet-843	17	27	)	)	PUNCT
admet-843	17	28	are	be	AUX
admet-843	17	29	drug	drug	NOUN
admet-843	17	30	delivery	delivery	NOUN
admet-843	17	31	systems	system	NOUN
admet-843	17	32	,	,	PUNCT
admet-843	17	33	suture	suture	NOUN
admet-843	17	34	threads	thread	NOUN
admet-843	17	35	,	,	PUNCT
admet-843	17	36	bone	bone	NOUN
admet-843	17	37	fixation	fixation	NOUN
admet-843	17	38	screws	screw	NOUN
admet-843	17	39	[	[	X
admet-843	17	40	3	3	NUM
admet-843	17	41	]	]	PUNCT
admet-843	17	42	.	.	PUNCT
admet-843	18	1	pla	pla	PROPN
admet-843	18	2	is	be	AUX
admet-843	18	3	degraded	degrade	VERB
admet-843	18	4	in	in	ADP
admet-843	18	5	situ	situ	NOUN
admet-843	18	6	through	through	ADP
admet-843	18	7	hydrolysis	hydrolysis	NOUN
admet-843	18	8	with	with	ADP
admet-843	18	9	the	the	DET
admet-843	18	10	production	production	NOUN
admet-843	18	11	of	of	ADP
admet-843	18	12	oligomers	oligomer	NOUN
admet-843	18	13	which	which	PRON
admet-843	18	14	are	be	AUX
admet-843	18	15	more	more	ADJ
admet-843	18	16	water	water	NOUN
admet-843	18	17	-	-	PUNCT
admet-843	18	18	soluble	soluble	ADJ
admet-843	18	19	.	.	PUNCT
admet-843	19	1	depending	depend	VERB
admet-843	19	2	on	on	ADP
admet-843	19	3	the	the	DET
admet-843	19	4	extent	extent	NOUN
admet-843	19	5	of	of	ADP
admet-843	19	6	hydrolysis	hydrolysis	NOUN
admet-843	19	7	,	,	PUNCT
admet-843	19	8	the	the	DET
admet-843	19	9	products	product	NOUN
admet-843	19	10	can	can	AUX
admet-843	19	11	be	be	AUX
admet-843	19	12	short	short	ADJ
admet-843	19	13	oligomers	oligomer	NOUN
admet-843	19	14	(	(	PUNCT
admet-843	19	15	olas	olas	PROPN
admet-843	19	16	)	)	PUNCT
admet-843	19	17	and	and	CCONJ
admet-843	19	18	lactic	lactic	ADJ
admet-843	19	19	acid	acid	NOUN
admet-843	19	20	(	(	PUNCT
admet-843	19	21	2	2	NUM
admet-843	19	22	-	-	PUNCT
admet-843	19	23	hydroxypropanoic	hydroxypropanoic	VERB
admet-843	19	24	acid	acid	NOUN
admet-843	19	25	the	the	DET
admet-843	19	26	monomer	monomer	NOUN
admet-843	19	27	)	)	PUNCT
admet-843	20	1	[	[	X
admet-843	20	2	3,5	3,5	NUM
admet-843	20	3	]	]	PUNCT
admet-843	20	4	.	.	PUNCT
admet-843	21	1	lactic	lactic	ADJ
admet-843	21	2	acid	acid	NOUN
admet-843	21	3	is	be	AUX
admet-843	21	4	a	a	DET
admet-843	21	5	nontoxic	nontoxic	ADJ
admet-843	21	6	compound	compound	NOUN
admet-843	21	7	and	and	CCONJ
admet-843	21	8	a	a	DET
admet-843	21	9	biochemical	biochemical	ADJ
admet-843	21	10	intermediate	intermediate	NOUN
admet-843	21	11	in	in	ADP
admet-843	21	12	carbohydrate	carbohydrate	ADJ
admet-843	21	13	metabolism	metabolism	NOUN
admet-843	22	1	[	[	X
admet-843	22	2	6	6	NUM
admet-843	22	3	]	]	PUNCT
admet-843	22	4	.	.	PUNCT
admet-843	23	1	the	the	DET
admet-843	23	2	oligomers	oligomer	NOUN
admet-843	23	3	produced	produce	VERB
admet-843	23	4	from	from	ADP
admet-843	23	5	hydrolysis	hydrolysis	NOUN
admet-843	23	6	may	may	AUX
admet-843	23	7	act	act	VERB
admet-843	23	8	as	as	ADP
admet-843	23	9	catalysts	catalyst	NOUN
admet-843	23	10	and	and	CCONJ
admet-843	23	11	they	they	PRON
admet-843	23	12	can	can	AUX
admet-843	23	13	diffuse	diffuse	VERB
admet-843	23	14	from	from	ADP
admet-843	23	15	the	the	DET
admet-843	23	16	sample	sample	NOUN
admet-843	23	17	toward	toward	ADP
admet-843	23	18	the	the	DET
admet-843	23	19	surfaces	surface	NOUN
admet-843	23	20	,	,	PUNCT
admet-843	23	21	these	these	DET
admet-843	23	22	phenomena	phenomenon	NOUN
admet-843	23	23	influencing	influence	VERB
admet-843	23	24	the	the	DET
admet-843	23	25	polymer	polymer	NOUN
admet-843	23	26	degradation	degradation	NOUN
admet-843	24	1	[	[	X
admet-843	24	2	3	3	NUM
admet-843	24	3	]	]	PUNCT
admet-843	24	4	.	.	PUNCT
admet-843	25	1	the	the	DET
admet-843	25	2	counter	counter	NOUN
admet-843	25	3	-	-	NOUN
admet-843	25	4	diffusion	diffusion	NOUN
admet-843	25	5	of	of	ADP
admet-843	25	6	the	the	DET
admet-843	25	7	larger	large	ADJ
admet-843	25	8	oligomers	oligomer	NOUN
admet-843	25	9	can	can	AUX
admet-843	25	10	be	be	AUX
admet-843	25	11	the	the	DET
admet-843	25	12	determining	determine	VERB
admet-843	25	13	phase	phase	NOUN
admet-843	25	14	for	for	ADP
admet-843	25	15	biodegradation	biodegradation	NOUN
admet-843	25	16	as	as	SCONJ
admet-843	25	17	the	the	DET
admet-843	25	18	oligomers	oligomer	NOUN
admet-843	25	19	having	have	VERB
admet-843	25	20	large	large	ADJ
admet-843	25	21	dimensions	dimension	NOUN
admet-843	25	22	can	can	AUX
admet-843	25	23	not	not	PART
admet-843	25	24	diffuse	diffuse	VERB
admet-843	25	25	fast	fast	ADV
admet-843	25	26	enough	enough	ADV
admet-843	25	27	.	.	PUNCT
admet-843	26	1	increased	increase	VERB
admet-843	26	2	solubility	solubility	NOUN
admet-843	26	3	of	of	ADP
admet-843	26	4	oligomers	oligomer	NOUN
admet-843	26	5	may	may	AUX
admet-843	26	6	facilitate	facilitate	VERB
admet-843	26	7	diffusion	diffusion	NOUN
admet-843	26	8	and	and	CCONJ
admet-843	26	9	consequently	consequently	ADV
admet-843	26	10	,	,	PUNCT
admet-843	26	11	the	the	DET
admet-843	26	12	biodegradability	biodegradability	NOUN
admet-843	26	13	of	of	ADP
admet-843	26	14	the	the	DET
admet-843	26	15	polymer	polymer	NOUN
admet-843	26	16	.	.	PUNCT
admet-843	27	1	it	it	PRON
admet-843	27	2	is	be	AUX
admet-843	27	3	already	already	ADV
admet-843	27	4	known	know	VERB
admet-843	27	5	that	that	SCONJ
admet-843	27	6	the	the	DET
admet-843	27	7	degradation	degradation	NOUN
admet-843	27	8	of	of	ADP
admet-843	27	9	biopolymers	biopolymer	NOUN
admet-843	27	10	is	be	AUX
admet-843	27	11	important	important	ADJ
admet-843	27	12	for	for	ADP
admet-843	27	13	controlled	control	VERB
admet-843	27	14	drug	drug	NOUN
admet-843	27	15	delivery	delivery	NOUN
admet-843	27	16	systems	system	NOUN
admet-843	27	17	and	and	CCONJ
admet-843	27	18	for	for	ADP
admet-843	27	19	various	various	ADJ
admet-843	27	20	types	type	NOUN
admet-843	27	21	of	of	ADP
admet-843	27	22	implants	implant	NOUN
admet-843	27	23	.	.	PUNCT
admet-843	28	1	biopolymers	biopolymer	NOUN
admet-843	28	2	can	can	AUX
admet-843	28	3	be	be	AUX
admet-843	28	4	degraded	degrade	VERB
admet-843	28	5	by	by	ADP
admet-843	28	6	random	random	ADJ
admet-843	28	7	chain	chain	NOUN
admet-843	28	8	scission	scission	NOUN
admet-843	28	9	to	to	ADP
admet-843	28	10	oligomers	oligomer	NOUN
admet-843	28	11	with	with	ADP
admet-843	28	12	lower	low	ADJ
admet-843	28	13	molecular	molecular	ADJ
admet-843	28	14	weight	weight	NOUN
admet-843	28	15	[	[	X
admet-843	28	16	7	7	NUM
admet-843	28	17	]	]	PUNCT
admet-843	28	18	.	.	PUNCT
admet-843	29	1	the	the	DET
admet-843	29	2	degradation	degradation	NOUN
admet-843	29	3	products	product	NOUN
admet-843	29	4	,	,	PUNCT
admet-843	29	5	the	the	DET
admet-843	29	6	oligomers	oligomer	NOUN
admet-843	29	7	,	,	PUNCT
admet-843	29	8	may	may	AUX
admet-843	29	9	also	also	ADV
admet-843	29	10	affect	affect	VERB
admet-843	29	11	the	the	DET
admet-843	29	12	human	human	ADJ
admet-843	29	13	organism	organism	NOUN
admet-843	29	14	,	,	PUNCT
admet-843	29	15	the	the	DET
admet-843	29	16	effects	effect	NOUN
admet-843	29	17	they	they	PRON
admet-843	29	18	produce	produce	VERB
admet-843	29	19	being	be	AUX
admet-843	29	20	dependent	dependent	ADJ
admet-843	29	21	on	on	ADP
admet-843	29	22	absorption	absorption	NOUN
admet-843	29	23	,	,	PUNCT
admet-843	29	24	distribution	distribution	NOUN
admet-843	29	25	,	,	PUNCT
admet-843	29	26	metabolism	metabolism	NOUN
admet-843	29	27	,	,	PUNCT
admet-843	29	28	excretion	excretion	NOUN
admet-843	29	29	and	and	CCONJ
admet-843	29	30	toxicity	toxicity	NOUN
admet-843	29	31	(	(	PUNCT
admet-843	29	32	admet	admet	ADJ
admet-843	29	33	)	)	PUNCT
admet-843	29	34	profile	profile	NOUN
admet-843	30	1	[	[	X
admet-843	30	2	8	8	NUM
admet-843	30	3	]	]	PUNCT
admet-843	30	4	.	.	PUNCT
admet-843	31	1	the	the	DET
admet-843	31	2	solubility	solubility	NOUN
admet-843	31	3	in	in	ADP
admet-843	31	4	aqueous	aqueous	ADJ
admet-843	31	5	media	medium	NOUN
admet-843	31	6	is	be	AUX
admet-843	31	7	one	one	NUM
admet-843	31	8	of	of	ADP
admet-843	31	9	the	the	DET
admet-843	31	10	most	most	ADV
admet-843	31	11	important	important	ADJ
admet-843	31	12	physicochemical	physicochemical	ADJ
admet-843	31	13	characteristics	characteristic	NOUN
admet-843	31	14	influencing	influence	VERB
admet-843	31	15	the	the	DET
admet-843	31	16	admet	admet	NOUN
admet-843	31	17	properties	property	NOUN
admet-843	31	18	[	[	X
admet-843	31	19	9,10	9,10	NUM
admet-843	31	20	]	]	X
admet-843	31	21	.	.	PUNCT
admet-843	32	1	the	the	DET
admet-843	32	2	soluble	soluble	ADJ
admet-843	32	3	degradation	degradation	NOUN
admet-843	32	4	products	product	NOUN
admet-843	32	5	are	be	AUX
admet-843	32	6	either	either	CCONJ
admet-843	32	7	metabolized	metabolize	VERB
admet-843	32	8	or	or	CCONJ
admet-843	32	9	transported	transport	VERB
admet-843	32	10	through	through	ADP
admet-843	32	11	the	the	DET
admet-843	32	12	lymphatic	lymphatic	ADJ
admet-843	32	13	system	system	NOUN
admet-843	32	14	to	to	ADP
admet-843	32	15	the	the	DET
admet-843	32	16	kidney	kidney	NOUN
admet-843	32	17	to	to	PART
admet-843	32	18	be	be	AUX
admet-843	32	19	excreted	excrete	VERB
admet-843	32	20	from	from	ADP
admet-843	32	21	the	the	DET
admet-843	32	22	organism	organism	NOUN
admet-843	33	1	[	[	X
admet-843	33	2	11	11	NUM
admet-843	33	3	]	]	PUNCT
admet-843	33	4	.	.	PUNCT
admet-843	34	1	pla	pla	PROPN
admet-843	34	2	is	be	AUX
admet-843	34	3	known	know	VERB
admet-843	34	4	as	as	ADP
admet-843	34	5	a	a	DET
admet-843	34	6	biodegradable	biodegradable	ADJ
admet-843	34	7	,	,	PUNCT
admet-843	34	8	biocompatible	biocompatible	ADJ
admet-843	34	9	,	,	PUNCT
admet-843	34	10	non	non	ADJ
admet-843	34	11	-	-	ADJ
admet-843	34	12	toxic	toxic	ADJ
admet-843	34	13	and	and	CCONJ
admet-843	34	14	eco	eco	NOUN
admet-843	34	15	-	-	PUNCT
admet-843	34	16	friendly	friendly	ADJ
admet-843	34	17	polymer	polymer	NOUN
admet-843	34	18	[	[	X
admet-843	34	19	12	12	NUM
admet-843	34	20	]	]	PUNCT
admet-843	34	21	but	but	CCONJ
admet-843	34	22	there	there	PRON
admet-843	34	23	is	be	VERB
admet-843	34	24	a	a	DET
admet-843	34	25	recent	recent	ADJ
admet-843	34	26	in	in	ADP
admet-843	34	27	vitro	vitro	X
admet-843	34	28	study	study	NOUN
admet-843	34	29	revealing	reveal	VERB
admet-843	34	30	some	some	DET
admet-843	34	31	toxic	toxic	ADJ
admet-843	34	32	effects	effect	NOUN
admet-843	34	33	of	of	ADP
admet-843	34	34	pla	pla	NOUN
admet-843	35	1	[	[	X
admet-843	35	2	13	13	NUM
admet-843	35	3	]	]	X
admet-843	35	4	:	:	PUNCT
admet-843	35	5	pla	pla	PROPN
admet-843	35	6	inhibited	inhibit	VERB
admet-843	35	7	bioluminescence	bioluminescence	NOUN
admet-843	35	8	(	(	PUNCT
admet-843	35	9	an	an	DET
admet-843	35	10	endpoint	endpoint	NOUN
admet-843	35	11	illustrating	illustrate	VERB
admet-843	35	12	cytotoxicity	cytotoxicity	NOUN
admet-843	35	13	in	in	ADP
admet-843	35	14	mammalian	mammalian	ADJ
admet-843	35	15	cells	cell	NOUN
admet-843	35	16	)	)	PUNCT
admet-843	35	17	with	with	ADP
admet-843	35	18	high	high	ADJ
admet-843	35	19	efficiency	efficiency	NOUN
admet-843	35	20	,	,	PUNCT
admet-843	35	21	induced	induce	VERB
admet-843	35	22	an	an	DET
admet-843	35	23	oxidative	oxidative	ADJ
admet-843	35	24	stress	stress	NOUN
admet-843	35	25	response	response	NOUN
admet-843	35	26	and	and	CCONJ
admet-843	35	27	it	it	PRON
admet-843	35	28	contains	contain	VERB
admet-843	35	29	estrogenic	estrogenic	ADJ
admet-843	35	30	compounds	compound	NOUN
admet-843	35	31	.	.	PUNCT
admet-843	36	1	to	to	ADP
admet-843	36	2	the	the	DET
admet-843	36	3	best	good	ADJ
admet-843	36	4	of	of	ADP
admet-843	36	5	our	our	PRON
admet-843	36	6	knowledge	knowledge	NOUN
admet-843	36	7	,	,	PUNCT
admet-843	36	8	there	there	PRON
admet-843	36	9	are	be	VERB
admet-843	36	10	no	no	DET
admet-843	36	11	available	available	ADJ
admet-843	36	12	studies	study	NOUN
admet-843	36	13	concerning	concern	VERB
admet-843	36	14	the	the	DET
admet-843	36	15	biological	biological	ADJ
admet-843	36	16	effects	effect	NOUN
admet-843	36	17	of	of	ADP
admet-843	36	18	olas	olas	PROPN
admet-843	36	19	.	.	PUNCT
admet-843	37	1	taking	take	VERB
admet-843	37	2	into	into	ADP
admet-843	37	3	account	account	NOUN
admet-843	37	4	this	this	DET
admet-843	37	5	information	information	NOUN
admet-843	37	6	,	,	PUNCT
admet-843	37	7	the	the	DET
admet-843	37	8	aim	aim	NOUN
admet-843	37	9	of	of	ADP
admet-843	37	10	this	this	DET
admet-843	37	11	study	study	NOUN
admet-843	37	12	is	be	AUX
admet-843	37	13	to	to	PART
admet-843	37	14	predict	predict	VERB
admet-843	37	15	the	the	DET
admet-843	37	16	aqueous	aqueous	ADJ
admet-843	37	17	solubility	solubility	NOUN
admet-843	37	18	and	and	CCONJ
admet-843	37	19	admet	admet	NOUN
admet-843	37	20	profiles	profile	NOUN
admet-843	37	21	for	for	ADP
admet-843	37	22	short	short	ADJ
admet-843	37	23	oligomers	oligomer	NOUN
admet-843	37	24	(	(	PUNCT
admet-843	37	25	containing	contain	VERB
admet-843	37	26	up	up	ADP
admet-843	37	27	to	to	PART
admet-843	37	28	40	40	NUM
admet-843	37	29	monomeric	monomeric	ADJ
admet-843	37	30	units	unit	NOUN
admet-843	37	31	and	and	CCONJ
admet-843	37	32	having	have	VERB
admet-843	37	33	the	the	DET
admet-843	37	34	molecular	molecular	ADJ
admet-843	37	35	weight	weight	NOUN
admet-843	37	36	up	up	ADP
admet-843	37	37	to	to	PART
admet-843	37	38	3000	3000	NUM
admet-843	37	39	da	da	NOUN
admet-843	37	40	)	)	PUNCT
admet-843	37	41	resulted	result	VERB
admet-843	37	42	from	from	ADP
admet-843	37	43	the	the	DET
admet-843	37	44	degradation	degradation	NOUN
admet-843	37	45	of	of	ADP
admet-843	37	46	pla	pla	NOUN
admet-843	37	47	.	.	PUNCT
admet-843	38	1	our	our	PRON
admet-843	38	2	methodology	methodology	NOUN
admet-843	38	3	is	be	AUX
admet-843	38	4	based	base	VERB
admet-843	38	5	on	on	ADP
admet-843	38	6	the	the	DET
admet-843	38	7	fact	fact	NOUN
admet-843	38	8	that	that	SCONJ
admet-843	38	9	controlling	control	VERB
admet-843	38	10	agencies	agency	NOUN
admet-843	38	11	in	in	ADP
admet-843	38	12	the	the	DET
admet-843	38	13	field	field	NOUN
admet-843	38	14	of	of	ADP
admet-843	38	15	drug	drug	NOUN
admet-843	38	16	and	and	CCONJ
admet-843	38	17	medical	medical	ADJ
admet-843	38	18	devices	device	NOUN
admet-843	38	19	development	development	NOUN
admet-843	38	20	have	have	AUX
admet-843	38	21	confidence	confidence	NOUN
admet-843	38	22	in	in	ADP
admet-843	38	23	the	the	DET
admet-843	38	24	results	result	NOUN
admet-843	38	25	obtained	obtain	VERB
admet-843	38	26	by	by	ADP
admet-843	38	27	the	the	DET
admet-843	38	28	use	use	NOUN
admet-843	38	29	of	of	ADP
admet-843	38	30	computational	computational	ADJ
admet-843	38	31	tools	tool	NOUN
admet-843	38	32	for	for	ADP
admet-843	38	33	the	the	DET
admet-843	38	34	prediction	prediction	NOUN
admet-843	38	35	of	of	ADP
admet-843	38	36	the	the	DET
admet-843	38	37	biological	biological	ADJ
admet-843	38	38	effects	effect	NOUN
admet-843	38	39	.	.	PUNCT
admet-843	39	1	method	method	NOUN
admet-843	39	2	within	within	ADP
admet-843	39	3	this	this	DET
admet-843	39	4	study	study	NOUN
admet-843	39	5	,	,	PUNCT
admet-843	39	6	we	we	PRON
admet-843	39	7	have	have	AUX
admet-843	39	8	considered	consider	VERB
admet-843	39	9	short	short	ADJ
admet-843	39	10	pla	pla	NOUN
admet-843	39	11	oligomers	oligomer	NOUN
admet-843	39	12	(	(	PUNCT
admet-843	39	13	olas	olas	PROPN
admet-843	39	14	)	)	PUNCT
admet-843	39	15	containing	contain	VERB
admet-843	39	16	from	from	ADP
admet-843	39	17	1	1	NUM
admet-843	39	18	to	to	PART
admet-843	39	19	40	40	NUM
admet-843	39	20	lactic	lactic	ADJ
admet-843	39	21	acid	acid	NOUN
admet-843	39	22	units	unit	NOUN
admet-843	39	23	.	.	PUNCT
admet-843	40	1	we	we	PRON
admet-843	40	2	used	use	VERB
admet-843	40	3	the	the	DET
admet-843	40	4	swissadme	swissadme	PROPN
admet-843	40	5	computational	computational	ADJ
admet-843	40	6	facility	facility	NOUN
admet-843	40	7	[	[	X
admet-843	40	8	14	14	NUM
admet-843	40	9	]	]	PUNCT
admet-843	40	10	to	to	PART
admet-843	40	11	predict	predict	VERB
admet-843	40	12	the	the	DET
admet-843	40	13	values	value	NOUN
admet-843	40	14	of	of	ADP
admet-843	40	15	their	their	PRON
admet-843	40	16	decimal	decimal	ADJ
admet-843	40	17	logarithm	logarithm	NOUN
admet-843	40	18	of	of	ADP
admet-843	40	19	the	the	DET
admet-843	40	20	molar	molar	ADJ
admet-843	40	21	solubility	solubility	NOUN
admet-843	40	22	in	in	ADP
admet-843	40	23	water	water	NOUN
admet-843	40	24	(	(	PUNCT
admet-843	40	25	log	log	VERB
admet-843	40	26	s	s	PART
admet-843	40	27	)	)	PUNCT
admet-843	40	28	and	and	CCONJ
admet-843	40	29	their	their	PRON
admet-843	40	30	admet	admet	NOUN
admet-843	40	31	properties	property	NOUN
admet-843	40	32	.	.	PUNCT
admet-843	41	1	three	three	NUM
admet-843	41	2	methods	method	NOUN
admet-843	41	3	are	be	AUX
admet-843	41	4	included	include	VERB
admet-843	41	5	in	in	ADP
admet-843	41	6	swissadme	swissadme	NOUN
admet-843	41	7	to	to	PART
admet-843	41	8	predict	predict	VERB
admet-843	41	9	aqueous	aqueous	ADJ
admet-843	41	10	solubility	solubility	NOUN
admet-843	41	11	:	:	PUNCT
admet-843	41	12	the	the	DET
admet-843	41	13	estimate	estimate	NOUN
admet-843	41	14	solubility	solubility	NOUN
admet-843	41	15	(	(	PUNCT
admet-843	41	16	esol	esol	PROPN
admet-843	41	17	)	)	PUNCT
admet-843	41	18	model	model	NOUN
admet-843	42	1	[	[	X
admet-843	42	2	15	15	NUM
admet-843	42	3	]	]	X
admet-843	42	4	,	,	PUNCT
admet-843	42	5	a	a	DET
admet-843	42	6	method	method	NOUN
admet-843	42	7	adapted	adapt	VERB
admet-843	42	8	from	from	ADP
admet-843	42	9	ali	ali	PROPN
admet-843	42	10	and	and	CCONJ
admet-843	42	11	co	co	NOUN
admet-843	42	12	-	-	NOUN
admet-843	42	13	workers	worker	NOUN
admet-843	42	14	[	[	X
admet-843	42	15	16	16	NUM
admet-843	42	16	]	]	PUNCT
admet-843	42	17	,	,	PUNCT
admet-843	42	18	and	and	CCONJ
admet-843	42	19	a	a	DET
admet-843	42	20	method	method	NOUN
admet-843	42	21	based	base	VERB
admet-843	42	22	on	on	ADP
admet-843	42	23	a	a	DET
admet-843	42	24	system	system	NOUN
admet-843	42	25	of	of	ADP
admet-843	42	26	16	16	NUM
admet-843	42	27	fragmental	fragmental	ADJ
admet-843	42	28	contributions	contribution	NOUN
admet-843	42	29	modulated	modulate	VERB
admet-843	42	30	by	by	ADP
admet-843	42	31	the	the	DET
admet-843	42	32	squared	square	VERB
admet-843	42	33	root	root	NOUN
admet-843	42	34	of	of	ADP
admet-843	42	35	molecular	molecular	ADJ
admet-843	42	36	weight	weight	NOUN
admet-843	42	37	implemented	implement	VERB
admet-843	42	38	under	under	ADP
admet-843	42	39	filter	filter	NOUN
admet-843	42	40	-	-	PUNCT
admet-843	42	41	it	it	PRON
admet-843	42	42	software	software	NOUN
admet-843	42	43	,	,	PUNCT
admet-843	42	44	version	version	NOUN
admet-843	42	45	1.0.2	1.0.2	PROPN
admet-843	42	46	(	(	PUNCT
admet-843	42	47	http://silicos-it.be.s3-website-eu-west-1.amazonaws.com/software/filter-it/1.0.2/filter-it.html	http://silicos-it.be.s3-website-eu-west-1.amazonaws.com/software/filter-it/1.0.2/filter-it.html	NOUN
admet-843	42	48	)	)	PUNCT
admet-843	42	49	.	.	PUNCT
admet-843	43	1	esol	esol	PROPN
admet-843	43	2	is	be	AUX
admet-843	43	3	a	a	DET
admet-843	43	4	method	method	NOUN
admet-843	43	5	used	use	VERB
admet-843	43	6	for	for	ADP
admet-843	43	7	estimating	estimate	VERB
admet-843	43	8	the	the	DET
admet-843	43	9	aqueous	aqueous	ADJ
admet-843	43	10	solubility	solubility	NOUN
admet-843	43	11	starting	start	VERB
admet-843	43	12	from	from	ADP
admet-843	43	13	its	its	PRON
admet-843	43	14	molecular	molecular	ADJ
admet-843	43	15	topology	topology	NOUN
admet-843	43	16	[	[	X
admet-843	43	17	15	15	NUM
admet-843	43	18	]	]	PUNCT
admet-843	43	19	and	and	CCONJ
admet-843	43	20	is	be	AUX
admet-843	43	21	based	base	VERB
admet-843	43	22	on	on	ADP
admet-843	43	23	4	4	NUM
admet-843	43	24	molecular	molecular	ADJ
admet-843	43	25	descriptors	descriptor	NOUN
admet-843	43	26	:	:	PUNCT
admet-843	43	27	the	the	DET
admet-843	43	28	computed	computed	ADJ
admet-843	43	29	partition	partition	NOUN
admet-843	43	30	coefficient	coefficient	NOUN
admet-843	43	31	(	(	PUNCT
admet-843	43	32	clogp	clogp	ADJ
admet-843	43	33	)	)	PUNCT
admet-843	43	34	,	,	PUNCT
admet-843	43	35	the	the	DET
admet-843	43	36	molecular	molecular	ADJ
admet-843	43	37	weight	weight	NOUN
admet-843	43	38	(	(	PUNCT
admet-843	43	39	mw	mw	PROPN
admet-843	43	40	)	)	PUNCT
admet-843	43	41	,	,	PUNCT
admet-843	43	42	the	the	DET
admet-843	43	43	number	number	NOUN
admet-843	43	44	of	of	ADP
admet-843	43	45	rotatable	rotatable	ADJ
admet-843	43	46	bonds	bond	NOUN
admet-843	43	47	(	(	PUNCT
admet-843	43	48	rb	rb	NOUN
admet-843	43	49	)	)	PUNCT
admet-843	43	50	and	and	CCONJ
admet-843	43	51	the	the	DET
admet-843	43	52	proportion	proportion	NOUN
admet-843	43	53	of	of	ADP
admet-843	43	54	heavy	heavy	ADJ
admet-843	43	55	atoms	atom	NOUN
admet-843	43	56	in	in	ADP
admet-843	43	57	aromatic	aromatic	ADJ
admet-843	43	58	systems	system	NOUN
admet-843	43	59	(	(	PUNCT
admet-843	43	60	ap	ap	PROPN
admet-843	43	61	)	)	PUNCT
admet-843	44	1	[	[	X
admet-843	44	2	15	15	NUM
admet-843	44	3	]	]	PUNCT
admet-843	44	4	.	.	PUNCT
admet-843	45	1	the	the	DET
admet-843	45	2	equation	equation	NOUN
admet-843	45	3	allowing	allow	VERB
admet-843	45	4	the	the	DET
admet-843	45	5	computation	computation	NOUN
admet-843	45	6	of	of	ADP
admet-843	45	7	logs	log	NOUN
admet-843	45	8	taking	take	VERB
admet-843	45	9	into	into	ADP
admet-843	45	10	account	account	NOUN
admet-843	45	11	these	these	DET
admet-843	45	12	descriptors	descriptor	NOUN
admet-843	45	13	is	be	AUX
admet-843	45	14	:	:	PUNCT
admet-843	45	15	figure	figure	NOUN
admet-843	45	16	1	1	NUM
admet-843	45	17	.	.	PUNCT
admet-843	46	1	the	the	DET
admet-843	46	2	structural	structural	ADJ
admet-843	46	3	formula	formula	NOUN
admet-843	46	4	of	of	ADP
admet-843	46	5	poly	poly	ADJ
admet-843	46	6	-	-	PUNCT
admet-843	46	7	lactic	lactic	ADJ
admet-843	46	8	acid	acid	NOUN
admet-843	46	9	http://silicos-it.be.s3-website-eu-west-1.amazonaws.com/software/filter-it/1.0.2/filter-it.html	http://silicos-it.be.s3-website-eu-west-1.amazonaws.com/software/filter-it/1.0.2/filter-it.html	PRON
admet-843	46	10	admet	admet	PROPN
admet-843	46	11	&	&	CCONJ
admet-843	46	12	dmpk	dmpk	PROPN
admet-843	46	13	8(4	8(4	NOUN
admet-843	46	14	)	)	PUNCT
admet-843	46	15	(	(	PUNCT
admet-843	46	16	2020	2020	NUM
admet-843	46	17	)	)	PUNCT
admet-843	46	18	425	425	NUM
admet-843	46	19	-	-	SYM
admet-843	46	20	436	436	NUM
admet-843	46	21	admet	admet	NOUN
admet-843	46	22	profiles	profile	NOUN
admet-843	46	23	of	of	ADP
admet-843	46	24	oligomers	oligomer	NOUN
admet-843	46	25	of	of	ADP
admet-843	46	26	lactic	lactic	ADJ
admet-843	46	27	acid	acid	NOUN
admet-843	46	28	doi	doi	NOUN
admet-843	46	29	:	:	PUNCT
admet-843	46	30	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	NOUN
admet-843	46	31	427	427	NUM
admet-843	46	32	wlog	wlog	NOUN
admet-843	46	33	0.16	0.16	NUM
admet-843	46	34	0.63	0.63	NUM
admet-843	46	35	log	log	NOUN
admet-843	46	36	0.062	0.062	NUM
admet-843	46	37	0.066	0.066	NUM
admet-843	46	38	0.74s	0.74s	NUM
admet-843	47	1	c	c	NOUN
admet-843	47	2	p	p	NOUN
admet-843	47	3	m	m	NOUN
admet-843	47	4	rb	rb	ADJ
admet-843	47	5	ap	ap	ADJ
admet-843	47	6			PROPN
admet-843	47	7			PROPN
admet-843	47	8			VERB
admet-843	47	9			NOUN
admet-843	47	10	.	.	PUNCT
admet-843	48	1	(	(	PUNCT
admet-843	48	2	1	1	X
admet-843	48	3	)	)	PUNCT
admet-843	48	4	the	the	DET
admet-843	48	5	model	model	NOUN
admet-843	48	6	introduced	introduce	VERB
admet-843	48	7	by	by	ADP
admet-843	48	8	ali	ali	PROPN
admet-843	48	9	and	and	CCONJ
admet-843	48	10	co	co	NOUN
admet-843	48	11	-	-	NOUN
admet-843	48	12	workers	worker	NOUN
admet-843	48	13	is	be	AUX
admet-843	48	14	based	base	VERB
admet-843	48	15	on	on	ADP
admet-843	48	16	two	two	NUM
admet-843	48	17	molecular	molecular	ADJ
admet-843	48	18	descriptors	descriptor	NOUN
admet-843	48	19	:	:	PUNCT
admet-843	48	20	log	log	VERB
admet-843	48	21	p	p	NOUN
admet-843	48	22	and	and	CCONJ
admet-843	48	23	topological	topological	ADJ
admet-843	48	24	polar	polar	ADJ
admet-843	48	25	surface	surface	NOUN
admet-843	48	26	area	area	NOUN
admet-843	48	27	(	(	PUNCT
admet-843	48	28	tpsa	tpsa	NOUN
admet-843	48	29	)	)	PUNCT
admet-843	49	1	[	[	X
admet-843	49	2	16	16	NUM
admet-843	49	3	]	]	X
admet-843	49	4	:	:	PUNCT
admet-843	49	5	log	log	NOUN
admet-843	49	6	1.0377log	1.0377log	NUM
admet-843	49	7	0.021	0.021	NUM
admet-843	49	8	0.4488s	0.4488s	PROPN
admet-843	49	9	p	p	PROPN
admet-843	49	10	tpsa	tpsa	PROPN
admet-843	49	11			PROPN
admet-843	49	12			PROPN
admet-843	49	13			PUNCT
admet-843	49	14	.	.	PUNCT
admet-843	50	1	(	(	PUNCT
admet-843	50	2	2	2	X
admet-843	50	3	)	)	PUNCT
admet-843	50	4	besides	besides	SCONJ
admet-843	50	5	the	the	DET
admet-843	50	6	contribution	contribution	NOUN
admet-843	50	7	of	of	ADP
admet-843	50	8	the	the	DET
admet-843	50	9	other	other	ADJ
admet-843	50	10	physicochemical	physicochemical	ADJ
admet-843	50	11	parameters	parameter	NOUN
admet-843	50	12	,	,	PUNCT
admet-843	50	13	these	these	DET
admet-843	50	14	equations	equation	NOUN
admet-843	50	15	consider	consider	VERB
admet-843	50	16	a	a	DET
admet-843	50	17	linear	linear	ADJ
admet-843	50	18	decrease	decrease	NOUN
admet-843	50	19	of	of	ADP
admet-843	50	20	the	the	DET
admet-843	50	21	logarithm	logarithm	NOUN
admet-843	50	22	of	of	ADP
admet-843	50	23	the	the	DET
admet-843	50	24	molar	molar	ADJ
admet-843	50	25	solubility	solubility	NOUN
admet-843	50	26	coefficient	coefficient	NOUN
admet-843	50	27	with	with	ADP
admet-843	50	28	mw	mw	NOUN
admet-843	50	29	and	and	CCONJ
admet-843	50	30	log	log	VERB
admet-843	50	31	p	p	PRON
admet-843	50	32	,	,	PUNCT
admet-843	50	33	respectively	respectively	ADV
admet-843	50	34	.	.	PUNCT
admet-843	51	1	the	the	DET
admet-843	51	2	calculation	calculation	NOUN
admet-843	51	3	of	of	ADP
admet-843	51	4	the	the	DET
admet-843	51	5	log	log	NOUN
admet-843	51	6	s	s	NOUN
admet-843	51	7	in	in	ADP
admet-843	51	8	filter	filter	NOUN
admet-843	51	9	-	-	PUNCT
admet-843	51	10	it	it	PRON
admet-843	51	11	software	software	NOUN
admet-843	51	12	is	be	AUX
admet-843	51	13	based	base	VERB
admet-843	51	14	on	on	ADP
admet-843	51	15	the	the	DET
admet-843	51	16	equation	equation	NOUN
admet-843	51	17	:	:	PUNCT
admet-843	51	18	w	w	X
admet-843	51	19	i	i	PRON
admet-843	51	20	ilog	ilog	VERB
admet-843	51	21	0.898	0.898	NUM
admet-843	51	22	0.104s	0.104s	NOUN
admet-843	51	23	m	m	PROPN
admet-843	51	24	w	w	PROPN
admet-843	51	25	c	c	PROPN
admet-843	51	26			ADV
admet-843	51	27			PUNCT
admet-843	51	28			PROPN
admet-843	51	29	,	,	PUNCT
admet-843	51	30	(	(	PUNCT
admet-843	51	31	3	3	X
admet-843	51	32	)	)	PUNCT
admet-843	51	33	where	where	SCONJ
admet-843	51	34	wi	wi	PROPN
admet-843	51	35	and	and	CCONJ
admet-843	51	36	ci	ci	PROPN
admet-843	51	37	are	be	AUX
admet-843	51	38	the	the	DET
admet-843	51	39	respective	respective	ADJ
admet-843	51	40	weights	weight	NOUN
admet-843	51	41	and	and	CCONJ
admet-843	51	42	counts	count	NOUN
admet-843	51	43	for	for	ADP
admet-843	51	44	the	the	DET
admet-843	51	45	fragment	fragment	NOUN
admet-843	51	46	i	i	PROPN
admet-843	51	47	,	,	PUNCT
admet-843	51	48	and	and	CCONJ
admet-843	51	49	mw	mw	X
admet-843	51	50	is	be	AUX
admet-843	51	51	the	the	DET
admet-843	51	52	molecular	molecular	ADJ
admet-843	51	53	weight	weight	NOUN
admet-843	51	54	of	of	ADP
admet-843	51	55	the	the	DET
admet-843	51	56	compound	compound	NOUN
admet-843	51	57	(	(	PUNCT
admet-843	51	58	http://silicos-it.be.s3-website-eu-west-1.amazonaws.com/software/filter-it/1.0.2/filterit.html	http://silicos-it.be.s3-website-eu-west-1.amazonaws.com/software/filter-it/1.0.2/filterit.html	PROPN
admet-843	51	59	)	)	PUNCT
admet-843	51	60	.	.	PUNCT
admet-843	52	1	swissadme	swissadme	PROPN
admet-843	52	2	computational	computational	ADJ
admet-843	52	3	tool	tool	NOUN
admet-843	52	4	uses	use	VERB
admet-843	52	5	for	for	ADP
admet-843	52	6	lipophilicity	lipophilicity	NOUN
admet-843	52	7	descriptor	descriptor	NOUN
admet-843	52	8	(	(	PUNCT
admet-843	52	9	log	log	VERB
admet-843	52	10	p	p	X
admet-843	52	11	)	)	PUNCT
admet-843	52	12	in	in	ADP
admet-843	52	13	equations	equation	NOUN
admet-843	52	14	(	(	PUNCT
admet-843	52	15	1	1	NUM
admet-843	52	16	)	)	PUNCT
admet-843	52	17	and	and	CCONJ
admet-843	52	18	(	(	PUNCT
admet-843	52	19	2	2	X
admet-843	52	20	)	)	PUNCT
admet-843	52	21	the	the	DET
admet-843	52	22	value	value	NOUN
admet-843	52	23	computed	compute	VERB
admet-843	52	24	using	use	VERB
admet-843	52	25	xlogp3	xlogp3	PROPN
admet-843	52	26	method	method	NOUN
admet-843	52	27	[	[	X
admet-843	52	28	17	17	NUM
admet-843	52	29	]	]	PUNCT
admet-843	52	30	.	.	PUNCT
admet-843	53	1	the	the	DET
admet-843	53	2	input	input	NOUN
admet-843	53	3	for	for	ADP
admet-843	53	4	the	the	DET
admet-843	53	5	swissadme	swissadme	PROPN
admet-843	53	6	tool	tool	NOUN
admet-843	53	7	is	be	AUX
admet-843	53	8	the	the	DET
admet-843	53	9	structure	structure	NOUN
admet-843	53	10	of	of	ADP
admet-843	53	11	a	a	DET
admet-843	53	12	chemical	chemical	NOUN
admet-843	53	13	compound	compound	NOUN
admet-843	53	14	in	in	ADP
admet-843	53	15	the	the	DET
admet-843	53	16	simplified	simplified	ADJ
admet-843	53	17	molecular	molecular	ADJ
admet-843	53	18	-	-	PUNCT
admet-843	53	19	input	input	NOUN
admet-843	53	20	line	line	NOUN
admet-843	53	21	-	-	PUNCT
admet-843	53	22	entry	entry	NOUN
admet-843	53	23	system	system	NOUN
admet-843	53	24	(	(	PUNCT
admet-843	53	25	smiles	smile	NOUN
admet-843	53	26	)	)	PUNCT
admet-843	53	27	format	format	NOUN
admet-843	53	28	.	.	PUNCT
admet-843	54	1	admet	admet	PROPN
admet-843	54	2	profiles	profile	NOUN
admet-843	54	3	,	,	PUNCT
admet-843	54	4	organ	organ	NOUN
admet-843	54	5	and	and	CCONJ
admet-843	54	6	genomic	genomic	NOUN
admet-843	54	7	toxicity	toxicity	NOUN
admet-843	54	8	of	of	ADP
admet-843	54	9	olas	ola	NOUN
admet-843	54	10	have	have	AUX
admet-843	54	11	been	be	AUX
admet-843	54	12	predicted	predict	VERB
admet-843	54	13	using	use	VERB
admet-843	54	14	admetsar2.0	admetsar2.0	PROPN
admet-843	54	15	[	[	X
admet-843	54	16	18,19	18,19	NUM
admet-843	54	17	]	]	PUNCT
admet-843	54	18	,	,	PUNCT
admet-843	54	19	pred	pre	VERB
admet-843	54	20	-	-	PUNCT
admet-843	54	21	h	h	NOUN
admet-843	54	22	-	-	PUNCT
admet-843	54	23	erg	erg	NOUN
admet-843	54	24	,	,	PUNCT
admet-843	54	25	pred	pre	VERB
admet-843	54	26	-	-	PUNCT
admet-843	54	27	skin	skin	NOUN
admet-843	54	28	[	[	X
admet-843	54	29	20,21	20,21	NUM
admet-843	54	30	]	]	PUNCT
admet-843	54	31	,	,	PUNCT
admet-843	54	32	endocrine	endocrine	NOUN
admet-843	54	33	disruptome	disruptome	NOUN
admet-843	55	1	[	[	X
admet-843	55	2	22	22	NUM
admet-843	55	3	]	]	PUNCT
admet-843	55	4	,	,	PUNCT
admet-843	55	5	toxtree	toxtree	NOUN
admet-843	56	1	[	[	X
admet-843	56	2	23	23	NUM
admet-843	56	3	]	]	PUNCT
admet-843	56	4	and	and	CCONJ
admet-843	56	5	carcino	carcino	NOUN
admet-843	56	6	-	-	PUNCT
admet-843	56	7	predel	predel	NOUN
admet-843	56	8	[	[	X
admet-843	56	9	24	24	NUM
admet-843	56	10	]	]	PUNCT
admet-843	56	11	.	.	PUNCT
admet-843	57	1	we	we	PRON
admet-843	57	2	have	have	AUX
admet-843	57	3	selected	select	VERB
admet-843	57	4	these	these	DET
admet-843	57	5	computational	computational	ADJ
admet-843	57	6	tools	tool	NOUN
admet-843	57	7	among	among	ADP
admet-843	57	8	the	the	DET
admet-843	57	9	numerous	numerous	ADJ
admet-843	57	10	available	available	ADJ
admet-843	57	11	facilities	facility	NOUN
admet-843	57	12	,	,	PUNCT
admet-843	57	13	as	as	SCONJ
admet-843	57	14	they	they	PRON
admet-843	57	15	have	have	VERB
admet-843	57	16	the	the	DET
admet-843	57	17	accuracy	accuracy	NOUN
admet-843	57	18	of	of	ADP
admet-843	57	19	prediction	prediction	NOUN
admet-843	57	20	usually	usually	ADV
admet-843	57	21	higher	high	ADJ
admet-843	57	22	than	than	ADP
admet-843	57	23	70	70	NUM
admet-843	57	24	%	%	NOUN
admet-843	57	25	and	and	CCONJ
admet-843	57	26	friendly	friendly	ADJ
admet-843	57	27	interfaces	interface	NOUN
admet-843	57	28	and	and	CCONJ
admet-843	57	29	tutorials	tutorial	NOUN
admet-843	57	30	that	that	PRON
admet-843	57	31	are	be	AUX
admet-843	57	32	available	available	ADJ
admet-843	57	33	for	for	ADP
admet-843	57	34	free	free	ADJ
admet-843	57	35	(	(	PUNCT
admet-843	57	36	online	online	ADJ
admet-843	57	37	or	or	CCONJ
admet-843	57	38	open	open	ADJ
admet-843	57	39	-	-	PUNCT
admet-843	57	40	source	source	NOUN
admet-843	57	41	)	)	PUNCT
admet-843	57	42	.	.	PUNCT
admet-843	58	1	a	a	DET
admet-843	58	2	short	short	ADJ
admet-843	58	3	description	description	NOUN
admet-843	58	4	of	of	ADP
admet-843	58	5	the	the	DET
admet-843	58	6	considered	consider	VERB
admet-843	58	7	computational	computational	ADJ
admet-843	58	8	tools	tool	NOUN
admet-843	58	9	is	be	AUX
admet-843	58	10	given	give	VERB
admet-843	58	11	in	in	ADP
admet-843	58	12	table	table	NOUN
admet-843	58	13	1	1	NUM
admet-843	58	14	.	.	PUNCT
admet-843	59	1	these	these	DET
admet-843	59	2	computational	computational	ADJ
admet-843	59	3	tools	tool	NOUN
admet-843	59	4	have	have	AUX
admet-843	59	5	been	be	AUX
admet-843	59	6	used	use	VERB
admet-843	59	7	for	for	ADP
admet-843	59	8	assessing	assess	VERB
admet-843	59	9	the	the	DET
admet-843	59	10	admet	admet	NOUN
admet-843	59	11	profiles	profile	NOUN
admet-843	59	12	and	and	CCONJ
admet-843	59	13	toxicological	toxicological	ADJ
admet-843	59	14	endpoints	endpoint	NOUN
admet-843	59	15	for	for	ADP
admet-843	59	16	numerous	numerous	ADJ
admet-843	59	17	classes	class	NOUN
admet-843	59	18	of	of	ADP
admet-843	59	19	chemicals	chemical	NOUN
admet-843	59	20	:	:	PUNCT
admet-843	59	21	chito	chito	NOUN
admet-843	59	22	-	-	NOUN
admet-843	59	23	oligomers	oligomer	NOUN
admet-843	59	24	[	[	X
admet-843	59	25	8	8	NUM
admet-843	59	26	]	]	PUNCT
admet-843	59	27	,	,	PUNCT
admet-843	59	28	synthetic	synthetic	ADJ
admet-843	59	29	steroids	steroid	NOUN
admet-843	60	1	[	[	X
admet-843	60	2	25	25	NUM
admet-843	60	3	]	]	PUNCT
admet-843	60	4	,	,	PUNCT
admet-843	60	5	cosmetic	cosmetic	ADJ
admet-843	60	6	ingredients	ingredient	NOUN
admet-843	60	7	[	[	X
admet-843	60	8	26,27	26,27	NUM
admet-843	60	9	]	]	PUNCT
admet-843	60	10	,	,	PUNCT
admet-843	60	11	pesticides	pesticide	VERB
admet-843	60	12	[	[	X
admet-843	60	13	26,28	26,28	NUM
admet-843	60	14	]	]	X
admet-843	60	15	,	,	PUNCT
admet-843	60	16	water	water	NOUN
admet-843	60	17	-	-	PUNCT
admet-843	60	18	soluble	soluble	ADJ
admet-843	60	19	derivatives	derivative	NOUN
admet-843	60	20	of	of	ADP
admet-843	60	21	chitosan	chitosan	NOUN
admet-843	60	22	[	[	X
admet-843	60	23	29	29	NUM
admet-843	60	24	]	]	PUNCT
admet-843	60	25	.	.	PUNCT
admet-843	61	1	it	it	PRON
admet-843	61	2	demonstrates	demonstrate	VERB
admet-843	61	3	their	their	PRON
admet-843	61	4	wide	wide	ADV
admet-843	61	5	-	-	PUNCT
admet-843	61	6	ranging	range	VERB
admet-843	61	7	applicability	applicability	NOUN
admet-843	61	8	.	.	PUNCT
admet-843	62	1	all	all	DET
admet-843	62	2	the	the	DET
admet-843	62	3	considered	consider	VERB
admet-843	62	4	computational	computational	ADJ
admet-843	62	5	tools	tool	NOUN
admet-843	62	6	use	use	VERB
admet-843	62	7	as	as	ADP
admet-843	62	8	inputs	input	NOUN
admet-843	62	9	smiles	smile	NOUN
admet-843	62	10	(	(	PUNCT
admet-843	62	11	simplified	simplify	VERB
admet-843	62	12	molecular	molecular	ADJ
admet-843	62	13	-	-	PUNCT
admet-843	62	14	input	input	NOUN
admet-843	62	15	line	line	NOUN
admet-843	62	16	-	-	PUNCT
admet-843	62	17	entry	entry	NOUN
admet-843	62	18	system	system	NOUN
admet-843	62	19	)	)	PUNCT
admet-843	62	20	formulas	formula	NOUN
admet-843	62	21	of	of	ADP
admet-843	62	22	the	the	DET
admet-843	62	23	oligomers	oligomer	NOUN
admet-843	62	24	under	under	ADP
admet-843	62	25	investigation	investigation	NOUN
admet-843	62	26	.	.	PUNCT
admet-843	63	1	these	these	DET
admet-843	63	2	formulas	formula	NOUN
admet-843	63	3	have	have	AUX
admet-843	63	4	been	be	AUX
admet-843	63	5	obtained	obtain	VERB
admet-843	63	6	using	use	VERB
admet-843	63	7	acd	acd	NOUN
admet-843	63	8	/	/	SYM
admet-843	63	9	chemsketch	chemsketch	NOUN
admet-843	63	10	utility	utility	NOUN
admet-843	63	11	(	(	PUNCT
admet-843	63	12	https://chemicalize.com	https://chemicalize.com	X
admet-843	63	13	accessed	access	VERB
admet-843	63	14	–	–	PUNCT
admet-843	63	15	accessed	access	VERB
admet-843	63	16	in	in	ADP
admet-843	63	17	march	march	PROPN
admet-843	63	18	2019	2019	NUM
admet-843	63	19	)	)	PUNCT
admet-843	63	20	.	.	PUNCT
admet-843	64	1	as	as	SCONJ
admet-843	64	2	it	it	PRON
admet-843	64	3	may	may	AUX
admet-843	64	4	be	be	AUX
admet-843	64	5	noticed	notice	VERB
admet-843	64	6	from	from	ADP
admet-843	64	7	table	table	NOUN
admet-843	64	8	1	1	NUM
admet-843	64	9	,	,	PUNCT
admet-843	64	10	none	none	NOUN
admet-843	64	11	of	of	ADP
admet-843	64	12	these	these	DET
admet-843	64	13	methods	method	NOUN
admet-843	64	14	considers	consider	VERB
admet-843	64	15	the	the	DET
admet-843	64	16	concentration	concentration	NOUN
admet-843	64	17	of	of	ADP
admet-843	64	18	the	the	DET
admet-843	64	19	investigated	investigate	VERB
admet-843	64	20	compound	compound	NOUN
admet-843	64	21	when	when	SCONJ
admet-843	64	22	making	make	VERB
admet-843	64	23	predictions	prediction	NOUN
admet-843	64	24	.	.	PUNCT
admet-843	65	1	this	this	PRON
admet-843	65	2	is	be	AUX
admet-843	65	3	one	one	NUM
admet-843	65	4	of	of	ADP
admet-843	65	5	the	the	DET
admet-843	65	6	limitations	limitation	NOUN
admet-843	65	7	of	of	ADP
admet-843	65	8	computational	computational	ADJ
admet-843	65	9	assessment	assessment	NOUN
admet-843	65	10	of	of	ADP
admet-843	65	11	biological	biological	ADJ
admet-843	65	12	effects	effect	NOUN
admet-843	65	13	of	of	ADP
admet-843	65	14	chemicals	chemical	NOUN
admet-843	65	15	based	base	VERB
admet-843	65	16	on	on	ADP
admet-843	65	17	expert	expert	NOUN
admet-843	65	18	rules	rule	NOUN
admet-843	65	19	and/or	and/or	CCONJ
admet-843	65	20	qsar	qsar	NOUN
admet-843	65	21	methods	method	NOUN
admet-843	65	22	.	.	PUNCT
admet-843	66	1	for	for	ADP
admet-843	66	2	scientific	scientific	ADJ
admet-843	66	3	graphing	graphing	NOUN
admet-843	66	4	and	and	CCONJ
admet-843	66	5	data	datum	NOUN
admet-843	66	6	analysis	analysis	NOUN
admet-843	66	7	we	we	PRON
admet-843	66	8	have	have	AUX
admet-843	66	9	used	use	VERB
admet-843	66	10	origin	origin	NOUN
admet-843	66	11	8.0	8.0	NUM
admet-843	66	12	software	software	NOUN
admet-843	66	13	.	.	PUNCT
admet-843	67	1	results	result	NOUN
admet-843	67	2	and	and	CCONJ
admet-843	67	3	discussions	discussion	NOUN
admet-843	67	4	pla	pla	NOUN
admet-843	67	5	is	be	AUX
admet-843	67	6	a	a	DET
admet-843	67	7	hydrophobic	hydrophobic	NOUN
admet-843	67	8	polymer	polymer	NOUN
admet-843	67	9	,	,	PUNCT
admet-843	67	10	its	its	PRON
admet-843	67	11	aqueous	aqueous	ADJ
admet-843	67	12	solubility	solubility	NOUN
admet-843	67	13	decreasing	decrease	VERB
admet-843	67	14	as	as	ADP
admet-843	67	15	its	its	PRON
admet-843	67	16	molecular	molecular	ADJ
admet-843	67	17	weight	weight	NOUN
admet-843	67	18	increases	increase	NOUN
admet-843	67	19	[	[	X
admet-843	67	20	5	5	NUM
admet-843	67	21	]	]	PUNCT
admet-843	67	22	.	.	PUNCT
admet-843	68	1	within	within	ADP
admet-843	68	2	this	this	DET
admet-843	68	3	study	study	NOUN
admet-843	68	4	,	,	PUNCT
admet-843	68	5	we	we	PRON
admet-843	68	6	have	have	AUX
admet-843	68	7	assessed	assess	VERB
admet-843	68	8	the	the	DET
admet-843	68	9	dependence	dependence	NOUN
admet-843	68	10	of	of	ADP
admet-843	68	11	the	the	DET
admet-843	68	12	logarithm	logarithm	NOUN
admet-843	68	13	of	of	ADP
admet-843	68	14	the	the	DET
admet-843	68	15	molar	molar	ADJ
admet-843	68	16	solubility	solubility	NOUN
admet-843	68	17	in	in	ADP
admet-843	68	18	water	water	NOUN
admet-843	68	19	(	(	PUNCT
admet-843	68	20	log	log	NOUN
admet-843	68	21	s	s	PART
admet-843	68	22	)	)	PUNCT
admet-843	68	23	of	of	ADP
admet-843	68	24	olas	ola	NOUN
admet-843	68	25	on	on	ADP
admet-843	68	26	the	the	DET
admet-843	68	27	molecular	molecular	ADJ
admet-843	68	28	weight	weight	NOUN
admet-843	68	29	and	and	CCONJ
admet-843	68	30	log	log	VERB
admet-843	68	31	p	p	PRON
admet-843	68	32	,	,	PUNCT
admet-843	68	33	respectively	respectively	ADV
admet-843	68	34	.	.	PUNCT
admet-843	69	1	the	the	DET
admet-843	69	2	swissadme	swissadme	PROPN
admet-843	69	3	tool	tool	PROPN
admet-843	69	4	allowed	allow	VERB
admet-843	69	5	to	to	PART
admet-843	69	6	compute	compute	VERB
admet-843	69	7	the	the	DET
admet-843	69	8	values	value	NOUN
admet-843	69	9	of	of	ADP
admet-843	69	10	the	the	DET
admet-843	69	11	logs	log	NOUN
admet-843	69	12	using	use	VERB
admet-843	69	13	the	the	DET
admet-843	69	14	three	three	NUM
admet-843	69	15	methods	method	NOUN
admet-843	69	16	described	describe	VERB
admet-843	69	17	above	above	ADV
admet-843	69	18	.	.	PUNCT
admet-843	70	1	the	the	DET
admet-843	70	2	obtained	obtain	VERB
admet-843	70	3	logs	logs	NOUN
admet-843	70	4	values	value	NOUN
admet-843	70	5	are	be	AUX
admet-843	70	6	plotted	plot	VERB
admet-843	70	7	against	against	ADP
admet-843	70	8	the	the	DET
admet-843	70	9	molecular	molecular	ADJ
admet-843	70	10	weight	weight	NOUN
admet-843	70	11	(	(	PUNCT
admet-843	70	12	figures	figure	NOUN
admet-843	70	13	2	2	NUM
admet-843	70	14	)	)	PUNCT
admet-843	70	15	and	and	CCONJ
admet-843	70	16	log	log	VERB
admet-843	70	17	p	p	NOUN
admet-843	70	18	(	(	PUNCT
admet-843	70	19	figures	figure	NOUN
admet-843	70	20	3	3	NUM
admet-843	70	21	)	)	PUNCT
admet-843	70	22	and	and	CCONJ
admet-843	70	23	they	they	PRON
admet-843	70	24	were	be	AUX
admet-843	70	25	fitted	fit	VERB
admet-843	70	26	with	with	ADP
admet-843	70	27	appropriate	appropriate	ADJ
admet-843	70	28	curves	curve	NOUN
admet-843	70	29	such	such	ADJ
admet-843	70	30	as	as	ADP
admet-843	70	31	to	to	PART
admet-843	70	32	obtain	obtain	VERB
admet-843	70	33	the	the	DET
admet-843	70	34	highest	high	ADJ
admet-843	70	35	values	value	NOUN
admet-843	70	36	of	of	ADP
admet-843	70	37	the	the	DET
admet-843	70	38	coefficients	coefficient	NOUN
admet-843	70	39	of	of	ADP
admet-843	70	40	determination	determination	NOUN
admet-843	70	41	(	(	PUNCT
admet-843	70	42	r	r	NOUN
admet-843	70	43	squared	square	VERB
admet-843	70	44	)	)	PUNCT
admet-843	70	45	.	.	PUNCT
admet-843	71	1	the	the	DET
admet-843	71	2	equations	equation	NOUN
admet-843	71	3	obtained	obtain	VERB
admet-843	71	4	by	by	ADP
admet-843	71	5	data	datum	NOUN
admet-843	71	6	analysis	analysis	NOUN
admet-843	71	7	are	be	AUX
admet-843	71	8	presented	present	VERB
admet-843	71	9	in	in	ADP
admet-843	71	10	table	table	NOUN
admet-843	71	11	2	2	NUM
admet-843	71	12	.	.	PUNCT
admet-843	72	1	for	for	ADP
admet-843	72	2	values	value	NOUN
admet-843	72	3	computed	compute	VERB
admet-843	72	4	using	use	VERB
admet-843	72	5	both	both	CCONJ
admet-843	72	6	esol	esol	NOUN
admet-843	72	7	and	and	CCONJ
admet-843	72	8	ali	ali	PROPN
admet-843	72	9	methods	method	NOUN
admet-843	72	10	,	,	PUNCT
admet-843	72	11	there	there	PRON
admet-843	72	12	is	be	VERB
admet-843	72	13	a	a	DET
admet-843	72	14	linear	linear	ADJ
admet-843	72	15	decrease	decrease	NOUN
admet-843	72	16	in	in	ADP
admet-843	72	17	the	the	DET
admet-843	72	18	logs	log	NOUN
admet-843	72	19	values	value	NOUN
admet-843	72	20	of	of	ADP
admet-843	72	21	olas	ola	NOUN
admet-843	72	22	with	with	ADP
admet-843	72	23	the	the	DET
admet-843	72	24	mw	mw	NOUN
admet-843	72	25	and	and	CCONJ
admet-843	72	26	logp	logp	NOUN
admet-843	72	27	respectively	respectively	ADV
admet-843	72	28	,	,	PUNCT
admet-843	72	29	the	the	DET
admet-843	72	30	decrease	decrease	NOUN
admet-843	72	31	described	describe	VERB
admet-843	72	32	by	by	ADP
admet-843	72	33	ali	ali	PROPN
admet-843	72	34	method	method	PROPN
admet-843	72	35	being	be	AUX
admet-843	72	36	more	more	ADV
admet-843	72	37	pronounced	pronounced	ADJ
admet-843	72	38	.	.	PUNCT
admet-843	73	1	the	the	DET
admet-843	73	2	silicos	silico	NOUN
admet-843	73	3	-	-	PUNCT
admet-843	73	4	it	it	PRON
admet-843	73	5	method	method	VERB
admet-843	73	6	conducts	conduct	NOUN
admet-843	73	7	to	to	ADP
admet-843	73	8	a	a	DET
admet-843	73	9	polynomial	polynomial	ADJ
admet-843	73	10	fit	fit	NOUN
admet-843	73	11	of	of	ADP
admet-843	73	12	order	order	NOUN
admet-843	73	13	3	3	NUM
admet-843	73	14	for	for	ADP
admet-843	73	15	the	the	DET
admet-843	73	16	variation	variation	NOUN
admet-843	73	17	of	of	ADP
admet-843	73	18	the	the	DET
admet-843	73	19	logs	log	NOUN
admet-843	73	20	with	with	ADP
admet-843	73	21	mw	mw	NOUN
admet-843	73	22	and	and	CCONJ
admet-843	73	23	log	log	VERB
admet-843	73	24	p	p	PRON
admet-843	73	25	,	,	PUNCT
admet-843	73	26	respectively	respectively	ADV
admet-843	73	27	(	(	PUNCT
admet-843	73	28	table	table	NOUN
admet-843	73	29	2	2	NUM
admet-843	73	30	)	)	PUNCT
admet-843	73	31	.	.	PUNCT
admet-843	74	1	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	ADV
admet-843	74	2	http://silicos-it.be.s3-website-eu-west-1.amazonaws.com/software/filter-it/1.0.2/filter-it.html	http://silicos-it.be.s3-website-eu-west-1.amazonaws.com/software/filter-it/1.0.2/filter-it.html	PRON
admet-843	74	3	http://silicos-it.be.s3-website-eu-west-1.amazonaws.com/software/filter-it/1.0.2/filter-it.html	http://silicos-it.be.s3-website-eu-west-1.amazonaws.com/software/filter-it/1.0.2/filter-it.html	NUM
admet-843	75	1	https://chemicalize.com/	https://chemicalize.com/	PROPN
admet-843	75	2	d.	d.	PROPN
admet-843	75	3	dascălu	dascălu	PROPN
admet-843	75	4	et	et	PROPN
admet-843	75	5	al	al	PROPN
admet-843	75	6	.	.	PROPN
admet-843	75	7	admet	admet	PROPN
admet-843	75	8	&	&	CCONJ
admet-843	75	9	dmpk	dmpk	PROPN
admet-843	75	10	8(4	8(4	NOUN
admet-843	75	11	)	)	PUNCT
admet-843	75	12	(	(	PUNCT
admet-843	75	13	2020	2020	NUM
admet-843	75	14	)	)	PUNCT
admet-843	75	15	425	425	NUM
admet-843	75	16	-	-	SYM
admet-843	75	17	436	436	NUM
admet-843	75	18	428	428	NUM
admet-843	75	19	table	table	NOUN
admet-843	75	20	1	1	NUM
admet-843	75	21	.	.	PUNCT
admet-843	75	22	short	short	ADJ
admet-843	75	23	presentation	presentation	NOUN
admet-843	75	24	of	of	ADP
admet-843	75	25	the	the	DET
admet-843	75	26	computational	computational	ADJ
admet-843	75	27	tools	tool	NOUN
admet-843	75	28	that	that	PRON
admet-843	75	29	were	be	AUX
admet-843	75	30	used	use	VERB
admet-843	75	31	in	in	ADP
admet-843	75	32	the	the	DET
admet-843	75	33	present	present	ADJ
admet-843	75	34	study	study	NOUN
admet-843	75	35	.	.	PUNCT
admet-843	76	1	qsar	qsar	PROPN
admet-843	76	2	–	–	PUNCT
admet-843	76	3	quantitative	quantitative	ADJ
admet-843	76	4	structure	structure	NOUN
admet-843	76	5	-	-	PUNCT
admet-843	76	6	activity	activity	NOUN
admet-843	76	7	relationship	relationship	NOUN
admet-843	76	8	tool	tool	NOUN
admet-843	76	9	method	method	VERB
admet-843	76	10	output	output	NOUN
admet-843	76	11	accuracy	accuracy	NOUN
admet-843	76	12	of	of	ADP
admet-843	76	13	predictions	prediction	NOUN
admet-843	76	14	,	,	PUNCT
admet-843	76	15	%	%	NOUN
admet-843	76	16	references	reference	NOUN
admet-843	76	17	swissadme	swissadme	PROPN
admet-843	76	18	expert	expert	NOUN
admet-843	76	19	-	-	PUNCT
admet-843	76	20	rules	rule	NOUN
admet-843	76	21	based	base	VERB
admet-843	76	22	2d	2d	NUM
admet-843	76	23	qsar	qsar	NOUN
admet-843	76	24	drug	drug	NOUN
admet-843	76	25	likeness	likeness	NOUN
admet-843	76	26	,	,	PUNCT
admet-843	76	27	pharmacokinetic	pharmacokinetic	ADJ
admet-843	76	28	profile	profile	NOUN
admet-843	76	29	specifying	specify	VERB
admet-843	76	30	yes	yes	INTJ
admet-843	76	31	or	or	CCONJ
admet-843	76	32	no	no	NOUN
admet-843	76	33	for	for	ADP
admet-843	76	34	every	every	DET
admet-843	76	35	investigated	investigate	VERB
admet-843	76	36	biological	biological	ADJ
admet-843	76	37	action	action	NOUN
admet-843	76	38	72	72	NUM
admet-843	76	39	-	-	SYM
admet-843	76	40	94	94	NUM
admet-843	77	1	[	[	X
admet-843	77	2	14	14	NUM
admet-843	77	3	]	]	PUNCT
admet-843	77	4	admetsar2.0	admetsar2.0	X
admet-843	77	5	2d	2d	NUM
admet-843	77	6	qsar	qsar	VERB
admet-843	77	7	pharmacokinetic	pharmacokinetic	ADJ
admet-843	77	8	profiles	profile	NOUN
admet-843	77	9	,	,	PUNCT
admet-843	77	10	organ	organ	NOUN
admet-843	77	11	(	(	PUNCT
admet-843	77	12	eye	eye	NOUN
admet-843	77	13	,	,	PUNCT
admet-843	77	14	heart	heart	NOUN
admet-843	77	15	,	,	PUNCT
admet-843	77	16	liver	liver	NOUN
admet-843	77	17	)	)	PUNCT
admet-843	77	18	and	and	CCONJ
admet-843	77	19	genomic	genomic	NOUN
admet-843	77	20	toxicity	toxicity	NOUN
admet-843	77	21	specifying	specify	VERB
admet-843	77	22	the	the	DET
admet-843	77	23	probability	probability	NOUN
admet-843	77	24	of	of	ADP
admet-843	77	25	the	the	DET
admet-843	77	26	presence	presence	NOUN
admet-843	77	27	or	or	CCONJ
admet-843	77	28	absence	absence	NOUN
admet-843	77	29	of	of	ADP
admet-843	77	30	a	a	DET
admet-843	77	31	biological	biological	ADJ
admet-843	77	32	action	action	NOUN
admet-843	77	33	.	.	PUNCT
admet-843	78	1	72	72	NUM
admet-843	78	2	-	-	SYM
admet-843	78	3	77	77	NUM
admet-843	78	4	[	[	X
admet-843	78	5	18,19	18,19	X
admet-843	78	6	]	]	X
admet-843	78	7	pred	pre	VERB
admet-843	78	8	-	-	PUNCT
admet-843	78	9	herg	herg	PROPN
admet-843	78	10	2d	2d	PROPN
admet-843	78	11	qsar	qsar	NOUN
admet-843	78	12	ability	ability	NOUN
admet-843	78	13	of	of	ADP
admet-843	78	14	a	a	DET
admet-843	78	15	chemical	chemical	NOUN
admet-843	78	16	compound	compound	NOUN
admet-843	78	17	to	to	PART
admet-843	78	18	inhibit	inhibit	VERB
admet-843	78	19	the	the	DET
admet-843	78	20	human	human	ADJ
admet-843	78	21	ether	ether	NOUN
admet-843	78	22	-	-	PUNCT
admet-843	78	23	à	à	NOUN
admet-843	78	24	-	-	ADJ
admet-843	78	25	go	go	NOUN
admet-843	78	26	-	-	PUNCT
admet-843	78	27	go	go	NOUN
admet-843	78	28	related	related	ADJ
admet-843	78	29	gene	gene	NOUN
admet-843	78	30	(	(	PUNCT
admet-843	78	31	herg)k+	herg)k+	NOUN
admet-843	78	32	channels	channel	NOUN
admet-843	78	33	using	use	VERB
admet-843	78	34	both	both	CCONJ
admet-843	78	35	a	a	DET
admet-843	78	36	binary	binary	NOUN
admet-843	78	37	and	and	CCONJ
admet-843	78	38	a	a	DET
admet-843	78	39	multiclass	multiclass	ADJ
admet-843	78	40	model	model	NOUN
admet-843	78	41	.	.	PUNCT
admet-843	79	1	70	70	NUM
admet-843	79	2	-	-	SYM
admet-843	79	3	89	89	NUM
admet-843	79	4	[	[	X
admet-843	79	5	21,30,31	21,30,31	NUM
admet-843	79	6	]	]	PUNCT
admet-843	79	7	pred	pre	VERB
admet-843	79	8	-	-	PUNCT
admet-843	79	9	skin	skin	NOUN
admet-843	79	10	2d	2d	NOUN
admet-843	79	11	-	-	PUNCT
admet-843	79	12	qsar	qsar	NOUN
admet-843	79	13	skin	skin	NOUN
admet-843	79	14	sensitization	sensitization	NOUN
admet-843	79	15	potential	potential	NOUN
admet-843	79	16	based	base	VERB
admet-843	79	17	on	on	ADP
admet-843	79	18	multiple	multiple	ADJ
admet-843	79	19	qsar	qsar	NOUN
admet-843	79	20	models	model	NOUN
admet-843	79	21	:	:	PUNCT
admet-843	79	22	prediction	prediction	NOUN
admet-843	79	23	by	by	ADP
admet-843	79	24	binary	binary	ADJ
admet-843	79	25	model	model	NOUN
admet-843	79	26	using	use	VERB
admet-843	79	27	human	human	ADJ
admet-843	79	28	data	datum	NOUN
admet-843	79	29	,	,	PUNCT
admet-843	79	30	binary	binary	ADJ
admet-843	79	31	and	and	CCONJ
admet-843	79	32	multiclass	multiclass	ADJ
admet-843	79	33	predictions	prediction	NOUN
admet-843	79	34	of	of	ADP
admet-843	79	35	murine	murine	ADJ
admet-843	79	36	skin	skin	NOUN
admet-843	79	37	sensitization	sensitization	NOUN
admet-843	79	38	potential	potential	NOUN
admet-843	79	39	based	base	VERB
admet-843	79	40	on	on	ADP
admet-843	79	41	animal	animal	NOUN
admet-843	79	42	data	datum	NOUN
admet-843	79	43	,	,	PUNCT
admet-843	79	44	and	and	CCONJ
admet-843	79	45	binary	binary	ADJ
admet-843	79	46	predictions	prediction	NOUN
admet-843	79	47	based	base	VERB
admet-843	79	48	on	on	ADP
admet-843	79	49	non	non	ADJ
admet-843	79	50	-	-	ADJ
admet-843	79	51	animal	animal	ADJ
admet-843	79	52	data	datum	NOUN
admet-843	79	53	,	,	PUNCT
admet-843	79	54	i.e	i.e	PRON
admet-843	79	55	direct	direct	ADJ
admet-843	79	56	peptide	peptide	NOUN
admet-843	79	57	reactivity	reactivity	NOUN
admet-843	79	58	assay	assay	NOUN
admet-843	79	59	(	(	PUNCT
admet-843	79	60	dpra	dpra	NOUN
admet-843	79	61	)	)	PUNCT
admet-843	79	62	,	,	PUNCT
admet-843	79	63	keratinosens	keratinosen	NOUN
admet-843	79	64	,	,	PUNCT
admet-843	79	65	and	and	CCONJ
admet-843	79	66	the	the	DET
admet-843	79	67	human	human	ADJ
admet-843	79	68	cell	cell	NOUN
admet-843	79	69	line	line	NOUN
admet-843	79	70	activation	activation	NOUN
admet-843	79	71	test	test	NOUN
admet-843	79	72	(	(	PUNCT
admet-843	79	73	h	h	NOUN
admet-843	79	74	-	-	PUNCT
admet-843	79	75	clat	clat	NOUN
admet-843	79	76	)	)	PUNCT
admet-843	79	77	]	]	PUNCT
admet-843	80	1	70	70	NUM
admet-843	80	2	-	-	SYM
admet-843	80	3	84	84	NUM
admet-843	80	4	[	[	X
admet-843	80	5	20,21,31	20,21,31	NUM
admet-843	80	6	]	]	SYM
admet-843	80	7	endocrine	endocrine	NOUN
admet-843	80	8	disruptome	disruptome	NOUN
admet-843	80	9	molecular	molecular	ADJ
admet-843	80	10	docking	docking	NOUN
admet-843	80	11	probability	probability	NOUN
admet-843	80	12	of	of	ADP
admet-843	80	13	binding	bind	VERB
admet-843	80	14	to	to	ADP
admet-843	80	15	nuclear	nuclear	ADJ
admet-843	80	16	receptors	receptor	NOUN
admet-843	80	17	.	.	PUNCT
admet-843	81	1	70	70	NUM
admet-843	81	2	-	-	SYM
admet-843	81	3	90	90	NUM
admet-843	81	4	[	[	SYM
admet-843	81	5	22	22	NUM
admet-843	81	6	]	]	PUNCT
admet-843	81	7	toxtree	toxtree	NOUN
admet-843	81	8	expert	expert	NOUN
admet-843	81	9	-	-	PUNCT
admet-843	81	10	rules	rule	NOUN
admet-843	81	11	based	base	VERB
admet-843	81	12	carcinogenic	carcinogenic	ADJ
admet-843	81	13	and	and	CCONJ
admet-843	81	14	mutagenic	mutagenic	ADJ
admet-843	81	15	potential	potential	NOUN
admet-843	81	16	expressed	express	VERB
admet-843	81	17	by	by	ADP
admet-843	81	18	yes	yes	INTJ
admet-843	81	19	or	or	CCONJ
admet-843	81	20	no	no	INTJ
admet-843	81	21	.	.	NOUN
admet-843	81	22	70	70	NUM
admet-843	82	1	[	[	X
admet-843	82	2	23	23	NUM
admet-843	82	3	]	]	PUNCT
admet-843	82	4	carcinopredel	carcinopredel	NOUN
admet-843	82	5	2d	2d	PROPN
admet-843	82	6	qsar	qsar	PROPN
admet-843	82	7	carcinogenic	carcinogenic	ADJ
admet-843	82	8	potential	potential	NOUN
admet-843	82	9	expressed	express	VERB
admet-843	82	10	by	by	ADP
admet-843	82	11	yes	yes	INTJ
admet-843	82	12	or	or	CCONJ
admet-843	82	13	no	no	INTJ
admet-843	82	14	.	.	NOUN
admet-843	82	15	70	70	NUM
admet-843	83	1	[	[	X
admet-843	83	2	24	24	NUM
admet-843	83	3	]	]	PUNCT
admet-843	83	4	figure	figure	NOUN
admet-843	83	5	2	2	NUM
admet-843	83	6	.	.	X
admet-843	83	7	solubility	solubility	NOUN
admet-843	83	8	in	in	ADP
admet-843	83	9	water	water	NOUN
admet-843	83	10	dependence	dependence	NOUN
admet-843	83	11	on	on	ADP
admet-843	83	12	the	the	DET
admet-843	83	13	molecular	molecular	ADJ
admet-843	83	14	weight	weight	NOUN
admet-843	83	15	of	of	ADP
admet-843	83	16	the	the	DET
admet-843	83	17	small	small	ADJ
admet-843	83	18	oligomers	oligomer	NOUN
admet-843	83	19	of	of	ADP
admet-843	83	20	pla	pla	NOUN
admet-843	83	21	:	:	PUNCT
admet-843	83	22	log	log	PROPN
admet-843	83	23	s	s	NOUN
admet-843	83	24	values	value	NOUN
admet-843	83	25	are	be	AUX
admet-843	83	26	computed	compute	VERB
admet-843	83	27	using	use	VERB
admet-843	83	28	esol	esol	PROPN
admet-843	83	29	and	and	CCONJ
admet-843	83	30	ali	ali	PROPN
admet-843	83	31	methods	method	NOUN
admet-843	83	32	(	(	PUNCT
admet-843	83	33	a	a	NOUN
admet-843	83	34	)	)	PUNCT
admet-843	83	35	and	and	CCONJ
admet-843	83	36	silicos	silico	NOUN
admet-843	83	37	-	-	PUNCT
admet-843	83	38	it	it	PRON
admet-843	83	39	method	method	NOUN
admet-843	83	40	(	(	PUNCT
admet-843	83	41	b	b	NOUN
admet-843	83	42	)	)	PUNCT
admet-843	83	43	.	.	PUNCT
admet-843	84	1	red	red	ADJ
admet-843	84	2	lines	line	NOUN
admet-843	84	3	correspond	correspond	VERB
admet-843	84	4	to	to	ADP
admet-843	84	5	the	the	DET
admet-843	84	6	fitting	fitting	NOUN
admet-843	84	7	of	of	ADP
admet-843	84	8	data	datum	NOUN
admet-843	84	9	,	,	PUNCT
admet-843	84	10	linear	linear	ADJ
admet-843	84	11	fit	fit	NOUN
admet-843	84	12	for	for	ADP
admet-843	84	13	the	the	DET
admet-843	84	14	values	value	NOUN
admet-843	84	15	obtained	obtain	VERB
admet-843	84	16	using	use	VERB
admet-843	84	17	esol	esol	PROPN
admet-843	84	18	and	and	CCONJ
admet-843	84	19	ali	ali	PROPN
admet-843	84	20	methods	method	NOUN
admet-843	84	21	(	(	PUNCT
admet-843	84	22	a	a	NOUN
admet-843	84	23	)	)	PUNCT
admet-843	84	24	and	and	CCONJ
admet-843	84	25	polynomial	polynomial	ADJ
admet-843	84	26	fit	fit	NOUN
admet-843	84	27	of	of	ADP
admet-843	84	28	order	order	NOUN
admet-843	84	29	3	3	NUM
admet-843	84	30	for	for	ADP
admet-843	84	31	the	the	DET
admet-843	84	32	values	value	NOUN
admet-843	84	33	obtained	obtain	VERB
admet-843	84	34	using	use	VERB
admet-843	84	35	silicos	silico	NOUN
admet-843	84	36	-	-	PUNCT
admet-843	84	37	it	it	PRON
admet-843	84	38	method	method	NOUN
admet-843	84	39	(	(	PUNCT
admet-843	84	40	b	b	NOUN
admet-843	84	41	)	)	PUNCT
admet-843	84	42	.	.	PUNCT
admet-843	85	1	admet	admet	PROPN
admet-843	85	2	&	&	CCONJ
admet-843	85	3	dmpk	dmpk	PROPN
admet-843	85	4	8(4	8(4	NOUN
admet-843	85	5	)	)	PUNCT
admet-843	85	6	(	(	PUNCT
admet-843	85	7	2020	2020	NUM
admet-843	85	8	)	)	PUNCT
admet-843	85	9	425	425	NUM
admet-843	85	10	-	-	SYM
admet-843	85	11	436	436	NUM
admet-843	85	12	admet	admet	NOUN
admet-843	85	13	profiles	profile	NOUN
admet-843	85	14	of	of	ADP
admet-843	85	15	oligomers	oligomer	NOUN
admet-843	85	16	of	of	ADP
admet-843	85	17	lactic	lactic	ADJ
admet-843	85	18	acid	acid	NOUN
admet-843	85	19	doi	doi	NOUN
admet-843	85	20	:	:	PUNCT
admet-843	85	21	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	ADP
admet-843	85	22	429	429	NUM
admet-843	85	23	figure	figure	NOUN
admet-843	85	24	3	3	NUM
admet-843	85	25	.	.	X
admet-843	85	26	solubility	solubility	NOUN
admet-843	85	27	in	in	ADP
admet-843	85	28	water	water	NOUN
admet-843	85	29	dependence	dependence	NOUN
admet-843	85	30	on	on	ADP
admet-843	85	31	the	the	DET
admet-843	85	32	log	log	NOUN
admet-843	85	33	p	p	NOUN
admet-843	85	34	values	value	NOUN
admet-843	85	35	for	for	ADP
admet-843	85	36	the	the	DET
admet-843	85	37	small	small	ADJ
admet-843	85	38	oligomers	oligomer	NOUN
admet-843	85	39	of	of	ADP
admet-843	85	40	pla	pla	NOUN
admet-843	85	41	:	:	PUNCT
admet-843	85	42	log	log	PROPN
admet-843	85	43	s	s	NOUN
admet-843	85	44	values	value	NOUN
admet-843	85	45	are	be	AUX
admet-843	85	46	computed	compute	VERB
admet-843	85	47	using	use	VERB
admet-843	85	48	esol	esol	PROPN
admet-843	85	49	and	and	CCONJ
admet-843	85	50	ali	ali	PROPN
admet-843	85	51	methods	method	NOUN
admet-843	85	52	(	(	PUNCT
admet-843	85	53	a	a	NOUN
admet-843	85	54	)	)	PUNCT
admet-843	85	55	and	and	CCONJ
admet-843	85	56	silicos	silico	NOUN
admet-843	85	57	-	-	PUNCT
admet-843	85	58	it	it	PRON
admet-843	85	59	method	method	NOUN
admet-843	85	60	(	(	PUNCT
admet-843	85	61	b	b	NOUN
admet-843	85	62	)	)	PUNCT
admet-843	85	63	.	.	PUNCT
admet-843	86	1	red	red	ADJ
admet-843	86	2	lines	line	NOUN
admet-843	86	3	correspond	correspond	VERB
admet-843	86	4	to	to	ADP
admet-843	86	5	the	the	DET
admet-843	86	6	fitting	fitting	NOUN
admet-843	86	7	of	of	ADP
admet-843	86	8	data	datum	NOUN
admet-843	86	9	,	,	PUNCT
admet-843	86	10	linear	linear	ADJ
admet-843	86	11	fit	fit	NOUN
admet-843	86	12	for	for	ADP
admet-843	86	13	the	the	DET
admet-843	86	14	values	value	NOUN
admet-843	86	15	obtained	obtain	VERB
admet-843	86	16	using	use	VERB
admet-843	86	17	esol	esol	PROPN
admet-843	86	18	and	and	CCONJ
admet-843	86	19	ali	ali	PROPN
admet-843	86	20	methods	method	NOUN
admet-843	86	21	(	(	PUNCT
admet-843	86	22	a	a	NOUN
admet-843	86	23	)	)	PUNCT
admet-843	86	24	and	and	CCONJ
admet-843	86	25	polynomial	polynomial	ADJ
admet-843	86	26	fit	fit	NOUN
admet-843	86	27	of	of	ADP
admet-843	86	28	order	order	NOUN
admet-843	86	29	3	3	NUM
admet-843	86	30	for	for	ADP
admet-843	86	31	the	the	DET
admet-843	86	32	values	value	NOUN
admet-843	86	33	obtained	obtain	VERB
admet-843	86	34	using	use	VERB
admet-843	86	35	silicos	silico	NOUN
admet-843	86	36	-	-	PUNCT
admet-843	86	37	it	it	PRON
admet-843	86	38	method	method	NOUN
admet-843	86	39	(	(	PUNCT
admet-843	86	40	b	b	NOUN
admet-843	86	41	)	)	PUNCT
admet-843	86	42	.	.	PUNCT
admet-843	87	1	table	table	NOUN
admet-843	87	2	2	2	NUM
admet-843	87	3	.	.	PUNCT
admet-843	88	1	equations	equation	NOUN
admet-843	88	2	corresponding	correspond	VERB
admet-843	88	3	to	to	ADP
admet-843	88	4	data	data	NOUN
admet-843	88	5	analysis	analysis	NOUN
admet-843	88	6	of	of	ADP
admet-843	88	7	the	the	DET
admet-843	88	8	molar	molar	ADJ
admet-843	88	9	solubility	solubility	NOUN
admet-843	88	10	in	in	ADP
admet-843	88	11	water	water	NOUN
admet-843	88	12	(	(	PUNCT
admet-843	88	13	log	log	NOUN
admet-843	88	14	s	s	PART
admet-843	88	15	)	)	PUNCT
admet-843	88	16	values	value	NOUN
admet-843	88	17	plotted	plot	VERB
admet-843	88	18	against	against	ADP
admet-843	88	19	molecular	molecular	ADJ
admet-843	88	20	weight	weight	NOUN
admet-843	88	21	(	(	PUNCT
admet-843	88	22	mw	mw	NOUN
admet-843	88	23	)	)	PUNCT
admet-843	88	24	and	and	CCONJ
admet-843	88	25	partition	partition	NOUN
admet-843	88	26	coefficient	coefficient	NOUN
admet-843	88	27	(	(	PUNCT
admet-843	88	28	log	log	VERB
admet-843	88	29	p	p	X
admet-843	88	30	)	)	PUNCT
admet-843	88	31	respectively	respectively	ADV
admet-843	88	32	for	for	ADP
admet-843	88	33	the	the	DET
admet-843	88	34	three	three	NUM
admet-843	88	35	used	use	VERB
admet-843	88	36	methods	method	NOUN
admet-843	88	37	to	to	PART
admet-843	88	38	compute	compute	VERB
admet-843	88	39	log	log	PROPN
admet-843	88	40	s	s	PART
admet-843	88	41	values	value	NOUN
admet-843	88	42	esol	esol	PROPN
admet-843	88	43	,	,	PUNCT
admet-843	88	44	ali	ali	PROPN
admet-843	88	45	and	and	CCONJ
admet-843	88	46	silicos	silico	NOUN
admet-843	88	47	-	-	PUNCT
admet-843	88	48	it	it	PRON
admet-843	88	49	.	.	PUNCT
admet-843	89	1	method/	method/	NUM
admet-843	89	2	parameter	parameter	NOUN
admet-843	89	3	mw	mw	INTJ
admet-843	89	4	log	log	NOUN
admet-843	89	5	p	p	NOUN
admet-843	89	6	equation	equation	NOUN
admet-843	89	7	r	r	NOUN
admet-843	89	8	2	2	NUM
admet-843	89	9	equation	equation	NOUN
admet-843	89	10	r	r	NOUN
admet-843	89	11	2	2	NUM
admet-843	89	12	esol	esol	NOUN
admet-843	89	13	log	log	NOUN
admet-843	89	14	s	s	NOUN
admet-843	89	15	=	=	NOUN
admet-843	89	16	0.61	0.61	NUM
admet-843	89	17	-	-	SYM
admet-843	89	18	0.006	0.006	NUM
admet-843	89	19	mw	mw	NOUN
admet-843	89	20	0.9996	0.9996	NUM
admet-843	89	21	log	log	NOUN
admet-843	89	22	s	s	PART
admet-843	89	23	=	=	NOUN
admet-843	89	24	-0.82	-0.82	NUM
admet-843	89	25	-	-	NOUN
admet-843	89	26	2.51log	2.51log	NUM
admet-843	89	27	p	p	NOUN
admet-843	89	28	0.9987	0.9987	NUM
admet-843	89	29	ali	ali	NOUN
admet-843	89	30	log	log	NOUN
admet-843	89	31	s	s	PART
admet-843	89	32	=	=	NOUN
admet-843	89	33	0.88	0.88	NUM
admet-843	89	34	-	-	PUNCT
admet-843	89	35	0.012	0.012	NUM
admet-843	89	36	mw	mw	NOUN
admet-843	89	37	0.9997	0.9997	NUM
admet-843	89	38	log	log	NOUN
admet-843	89	39	s	s	PART
admet-843	89	40	=	=	NOUN
admet-843	89	41	-1.92	-1.92	NOUN
admet-843	89	42	-	-	PUNCT
admet-843	89	43	4.89	4.89	NUM
admet-843	89	44	log	log	NOUN
admet-843	89	45	p	p	PROPN
admet-843	89	46	0.9989	0.9989	NUM
admet-843	89	47	silicos	silico	NOUN
admet-843	89	48	it	it	PRON
admet-843	89	49	log	log	VERB
admet-843	89	50	s	s	NOUN
admet-843	89	51	=	=	NOUN
admet-843	89	52	1.02	1.02	NUM
admet-843	89	53	-	-	SYM
admet-843	89	54	0.002	0.002	NUM
admet-843	89	55	mw	mw	NOUN
admet-843	89	56	+	+	ADP
admet-843	89	57	1.15.10	1.15.10	NUM
admet-843	89	58	-6	-6	INTJ
admet-843	89	59	mw	mw	INTJ
admet-843	89	60	2	2	NUM
admet-843	89	61	-1.8.10	-1.8.10	NOUN
admet-843	89	62	-10	-10	PUNCT
admet-843	89	63	mw	mw	VERB
admet-843	89	64	3	3	NUM
admet-843	89	65	0.9767	0.9767	NUM
admet-843	89	66	log	log	NOUN
admet-843	89	67	s	s	PART
admet-843	89	68	=	=	NOUN
admet-843	89	69	0.66	0.66	NUM
admet-843	89	70	-	-	SYM
admet-843	89	71	0.51	0.51	NUM
admet-843	89	72	log	log	NOUN
admet-843	89	73	p	p	NOUN
admet-843	90	1	+	+	CCONJ
admet-843	90	2	0.17	0.17	NUM
admet-843	90	3	log	log	NOUN
admet-843	90	4	p	p	NOUN
admet-843	90	5	2	2	NUM
admet-843	90	6	-0.012	-0.012	NOUN
admet-843	90	7	log	log	NOUN
admet-843	90	8	p	p	NOUN
admet-843	90	9	3	3	NUM
admet-843	90	10	0.9923	0.9923	NUM
admet-843	90	11	excepting	except	VERB
admet-843	90	12	the	the	DET
admet-843	90	13	lactic	lactic	ADJ
admet-843	90	14	acid	acid	NOUN
admet-843	90	15	,	,	PUNCT
admet-843	90	16	no	no	DET
admet-843	90	17	experimental	experimental	ADJ
admet-843	90	18	data	datum	NOUN
admet-843	90	19	on	on	ADP
admet-843	90	20	the	the	DET
admet-843	90	21	molar	molar	ADJ
admet-843	90	22	solubility	solubility	NOUN
admet-843	90	23	of	of	ADP
admet-843	90	24	the	the	DET
admet-843	90	25	other	other	ADJ
admet-843	90	26	olas	ola	NOUN
admet-843	90	27	were	be	AUX
admet-843	90	28	available	available	ADJ
admet-843	90	29	for	for	ADP
admet-843	90	30	comparison	comparison	NOUN
admet-843	90	31	and	and	CCONJ
admet-843	90	32	for	for	ADP
admet-843	90	33	evaluating	evaluate	VERB
admet-843	90	34	these	these	DET
admet-843	90	35	mathematical	mathematical	ADJ
admet-843	90	36	models	model	NOUN
admet-843	90	37	.	.	PUNCT
admet-843	91	1	taking	take	VERB
admet-843	91	2	into	into	ADP
admet-843	91	3	account	account	NOUN
admet-843	91	4	that	that	SCONJ
admet-843	91	5	the	the	DET
admet-843	91	6	aqueous	aqueous	ADJ
admet-843	91	7	solubility	solubility	NOUN
admet-843	91	8	of	of	ADP
admet-843	91	9	pla	pla	PROPN
admet-843	91	10	decreases	decrease	VERB
admet-843	91	11	with	with	ADP
admet-843	91	12	increasing	increase	VERB
admet-843	91	13	molecular	molecular	ADJ
admet-843	91	14	weight	weight	NOUN
admet-843	92	1	[	[	X
admet-843	92	2	5	5	NUM
admet-843	92	3	]	]	PUNCT
admet-843	92	4	and	and	CCONJ
admet-843	92	5	the	the	DET
admet-843	92	6	r2	r2	PROPN
admet-843	92	7	values	value	NOUN
admet-843	92	8	in	in	ADP
admet-843	92	9	table	table	NOUN
admet-843	92	10	2	2	NUM
admet-843	92	11	,	,	PUNCT
admet-843	92	12	ali	ali	PROPN
admet-843	92	13	method	method	PROPN
admet-843	92	14	seems	seem	VERB
admet-843	92	15	to	to	PART
admet-843	92	16	be	be	AUX
admet-843	92	17	appropriate	appropriate	ADJ
admet-843	92	18	to	to	PART
admet-843	92	19	be	be	AUX
admet-843	92	20	used	use	VERB
admet-843	92	21	to	to	PART
admet-843	92	22	predict	predict	VERB
admet-843	92	23	aqueous	aqueous	ADJ
admet-843	92	24	solubility	solubility	NOUN
admet-843	92	25	for	for	ADP
admet-843	92	26	olas	olas	PROPN
admet-843	92	27	.	.	PUNCT
admet-843	93	1	the	the	DET
admet-843	93	2	discrepancy	discrepancy	NOUN
admet-843	93	3	of	of	ADP
admet-843	93	4	the	the	DET
admet-843	93	5	three	three	NUM
admet-843	93	6	prediction	prediction	NOUN
admet-843	93	7	may	may	AUX
admet-843	93	8	come	come	VERB
admet-843	93	9	from	from	ADP
admet-843	93	10	the	the	DET
admet-843	93	11	data	data	NOUN
admet-843	93	12	sets	set	NOUN
admet-843	93	13	used	use	VERB
admet-843	93	14	to	to	PART
admet-843	93	15	derive	derive	VERB
admet-843	93	16	the	the	DET
admet-843	93	17	models	model	NOUN
admet-843	93	18	for	for	ADP
admet-843	93	19	predicting	predict	VERB
admet-843	93	20	the	the	DET
admet-843	93	21	solubility	solubility	NOUN
admet-843	93	22	values	value	NOUN
admet-843	93	23	.	.	PUNCT
admet-843	94	1	the	the	DET
admet-843	94	2	data	datum	NOUN
admet-843	94	3	set	set	VERB
admet-843	94	4	used	use	VERB
admet-843	94	5	to	to	PART
admet-843	94	6	derive	derive	VERB
admet-843	94	7	the	the	DET
admet-843	94	8	esol	esol	PROPN
admet-843	94	9	model	model	NOUN
admet-843	94	10	(	(	PUNCT
admet-843	94	11	2874	2874	NUM
admet-843	94	12	compounds	compound	NOUN
admet-843	94	13	,	,	PUNCT
admet-843	94	14	predictive	predictive	ADJ
admet-843	94	15	ability	ability	NOUN
admet-843	94	16	r2	r2	NOUN
admet-843	94	17	=	=	NOUN
admet-843	94	18	0.72	0.72	NUM
admet-843	94	19	)	)	PUNCT
admet-843	95	1	[	[	X
admet-843	95	2	15	15	NUM
admet-843	95	3	]	]	X
admet-843	95	4	is	be	AUX
admet-843	95	5	much	much	ADV
admet-843	95	6	larger	large	ADJ
admet-843	95	7	than	than	ADP
admet-843	95	8	the	the	DET
admet-843	95	9	data	datum	NOUN
admet-843	95	10	set	set	VERB
admet-843	95	11	(	(	PUNCT
admet-843	95	12	1265	1265	NUM
admet-843	95	13	compounds	compound	NOUN
admet-843	95	14	,	,	PUNCT
admet-843	95	15	predictive	predictive	ADJ
admet-843	95	16	ability	ability	NOUN
admet-843	95	17	r2	r2	NOUN
admet-843	95	18	=	=	NOUN
admet-843	95	19	0.869	0.869	NUM
admet-843	95	20	)	)	PUNCT
admet-843	95	21	being	be	AUX
admet-843	95	22	used	use	VERB
admet-843	95	23	in	in	ADP
admet-843	95	24	ali	ali	PROPN
admet-843	95	25	model	model	PROPN
admet-843	95	26	.	.	PUNCT
admet-843	96	1	the	the	DET
admet-843	96	2	ali	ali	PROPN
admet-843	96	3	model	model	PROPN
admet-843	96	4	uses	use	VERB
admet-843	96	5	experimentally	experimentally	ADV
admet-843	96	6	determined	determine	VERB
admet-843	96	7	logp	logp	NOUN
admet-843	96	8	values	value	NOUN
admet-843	96	9	and	and	CCONJ
admet-843	96	10	esol	esol	PROPN
admet-843	96	11	model	model	NOUN
admet-843	96	12	uses	use	VERB
admet-843	96	13	calculated	calculate	VERB
admet-843	96	14	logp	logp	NOUN
admet-843	96	15	values	value	NOUN
admet-843	96	16	(	(	PUNCT
admet-843	96	17	clogp	clogp	ADJ
admet-843	96	18	)	)	PUNCT
admet-843	96	19	.	.	PUNCT
admet-843	97	1	ali	ali	PROPN
admet-843	97	2	and	and	CCONJ
admet-843	97	3	his	his	PRON
admet-843	97	4	co	co	NOUN
admet-843	97	5	-	-	NOUN
admet-843	97	6	worker	worker	NOUN
admet-843	97	7	tested	test	VERB
admet-843	97	8	the	the	DET
admet-843	97	9	esol	esol	ADJ
admet-843	97	10	model	model	NOUN
admet-843	97	11	for	for	ADP
admet-843	97	12	489	489	NUM
admet-843	97	13	compounds	compound	NOUN
admet-843	97	14	with	with	ADP
admet-843	97	15	measured	measured	ADJ
admet-843	97	16	values	value	NOUN
admet-843	97	17	for	for	ADP
admet-843	97	18	logp	logp	NOUN
admet-843	97	19	,	,	PUNCT
admet-843	97	20	solubility	solubility	NOUN
admet-843	97	21	and	and	CCONJ
admet-843	97	22	melting	melting	NOUN
admet-843	97	23	points	point	NOUN
admet-843	97	24	,	,	PUNCT
admet-843	97	25	and	and	CCONJ
admet-843	97	26	there	there	PRON
admet-843	97	27	was	be	VERB
admet-843	97	28	an	an	DET
admet-843	97	29	improvement	improvement	NOUN
admet-843	97	30	of	of	ADP
admet-843	97	31	the	the	DET
admet-843	97	32	model	model	NOUN
admet-843	97	33	[	[	X
admet-843	97	34	16	16	NUM
admet-843	97	35	]	]	PUNCT
admet-843	97	36	.	.	PUNCT
admet-843	98	1	furthermore	furthermore	ADV
admet-843	98	2	,	,	PUNCT
admet-843	98	3	ali	ali	PROPN
admet-843	98	4	method	method	PROPN
admet-843	98	5	explicitly	explicitly	ADV
admet-843	98	6	accounts	account	VERB
admet-843	98	7	for	for	ADP
admet-843	98	8	the	the	DET
admet-843	98	9	effect	effect	NOUN
admet-843	98	10	of	of	ADP
admet-843	98	11	polar	polar	ADJ
admet-843	98	12	and	and	CCONJ
admet-843	98	13	polarizable	polarizable	ADJ
admet-843	98	14	atoms	atom	NOUN
admet-843	98	15	on	on	ADP
admet-843	98	16	aqueous	aqueous	ADJ
admet-843	98	17	solubility	solubility	NOUN
admet-843	98	18	.	.	PUNCT
admet-843	99	1	the	the	DET
admet-843	99	2	discrepancy	discrepancy	NOUN
admet-843	99	3	of	of	ADP
admet-843	99	4	the	the	DET
admet-843	99	5	prediction	prediction	NOUN
admet-843	99	6	models	model	NOUN
admet-843	99	7	also	also	ADV
admet-843	99	8	underlines	underline	VERB
admet-843	99	9	the	the	DET
admet-843	99	10	limitations	limitation	NOUN
admet-843	99	11	of	of	ADP
admet-843	99	12	the	the	DET
admet-843	99	13	in	in	ADP
admet-843	99	14	silico	silico	NOUN
admet-843	99	15	studies	study	NOUN
admet-843	99	16	and	and	CCONJ
admet-843	99	17	the	the	DET
admet-843	99	18	necessity	necessity	NOUN
admet-843	99	19	of	of	ADP
admet-843	99	20	further	further	ADJ
admet-843	99	21	experimental	experimental	ADJ
admet-843	99	22	measurements	measurement	NOUN
admet-843	99	23	such	such	ADJ
admet-843	99	24	as	as	ADP
admet-843	99	25	to	to	PART
admet-843	99	26	improve	improve	VERB
admet-843	99	27	our	our	PRON
admet-843	99	28	understanding	understanding	NOUN
admet-843	99	29	of	of	ADP
admet-843	99	30	olas	olas	PROPN
admet-843	99	31	solubility	solubility	PROPN
admet-843	99	32	.	.	PUNCT
admet-843	100	1	we	we	PRON
admet-843	100	2	have	have	AUX
admet-843	100	3	also	also	ADV
admet-843	100	4	assessed	assess	VERB
admet-843	100	5	the	the	DET
admet-843	100	6	admet	admet	NOUN
admet-843	100	7	properties	property	NOUN
admet-843	100	8	of	of	ADP
admet-843	100	9	short	short	ADJ
admet-843	100	10	olas	olas	PROPN
admet-843	100	11	.	.	PUNCT
admet-843	101	1	data	datum	NOUN
admet-843	101	2	obtained	obtain	VERB
admet-843	101	3	using	use	VERB
admet-843	101	4	admetsar2.0	admetsar2.0	PROPN
admet-843	101	5	and	and	CCONJ
admet-843	101	6	swissadme	swissadme	PROPN
admet-843	101	7	computational	computational	ADJ
admet-843	101	8	tools	tool	NOUN
admet-843	101	9	are	be	AUX
admet-843	101	10	illustrated	illustrate	VERB
admet-843	101	11	in	in	ADP
admet-843	101	12	tables	table	NOUN
admet-843	101	13	3	3	NUM
admet-843	101	14	and	and	CCONJ
admet-843	101	15	4	4	NUM
admet-843	101	16	.	.	NOUN
admet-843	101	17	numerical	numerical	PROPN
admet-843	101	18	data	data	PROPN
admet-843	101	19	represent	represent	VERB
admet-843	101	20	the	the	DET
admet-843	101	21	values	value	NOUN
admet-843	101	22	of	of	ADP
admet-843	101	23	the	the	DET
admet-843	101	24	probabilities	probability	NOUN
admet-843	101	25	that	that	PRON
admet-843	101	26	olas	ola	NOUN
admet-843	101	27	have	have	VERB
admet-843	101	28	(	(	PUNCT
admet-843	101	29	positive	positive	ADJ
admet-843	101	30	values	value	NOUN
admet-843	101	31	)	)	PUNCT
admet-843	101	32	or	or	CCONJ
admet-843	101	33	have	have	VERB
admet-843	101	34	not	not	PART
admet-843	101	35	(	(	PUNCT
admet-843	101	36	negative	negative	ADJ
admet-843	101	37	values	value	NOUN
admet-843	101	38	)	)	PUNCT
admet-843	101	39	a	a	DET
admet-843	101	40	certain	certain	ADJ
admet-843	101	41	biological	biological	ADJ
admet-843	101	42	action	action	NOUN
admet-843	101	43	.	.	PUNCT
admet-843	102	1	usually	usually	ADV
admet-843	102	2	,	,	PUNCT
admet-843	102	3	there	there	PRON
admet-843	102	4	is	be	VERB
admet-843	102	5	a	a	DET
admet-843	102	6	good	good	ADJ
admet-843	102	7	correlation	correlation	NOUN
admet-843	102	8	between	between	ADP
admet-843	102	9	the	the	DET
admet-843	102	10	predictions	prediction	NOUN
admet-843	102	11	obtained	obtain	VERB
admet-843	102	12	using	use	VERB
admet-843	102	13	the	the	DET
admet-843	102	14	two	two	NUM
admet-843	102	15	computational	computational	ADJ
admet-843	102	16	tools	tool	NOUN
admet-843	102	17	.	.	PUNCT
admet-843	103	1	furthermore	furthermore	ADV
admet-843	103	2	,	,	PUNCT
admet-843	103	3	many	many	ADJ
admet-843	103	4	of	of	ADP
admet-843	103	5	the	the	DET
admet-843	103	6	predictions	prediction	NOUN
admet-843	103	7	that	that	PRON
admet-843	103	8	we	we	PRON
admet-843	103	9	have	have	AUX
admet-843	103	10	obtained	obtain	VERB
admet-843	103	11	for	for	ADP
admet-843	103	12	olas	ola	NOUN
admet-843	103	13	are	be	AUX
admet-843	103	14	in	in	ADP
admet-843	103	15	good	good	ADJ
admet-843	103	16	agreement	agreement	NOUN
admet-843	103	17	with	with	ADP
admet-843	103	18	experimental	experimental	ADJ
admet-843	103	19	literature	literature	NOUN
admet-843	103	20	data	datum	NOUN
admet-843	103	21	concerning	concern	VERB
admet-843	103	22	the	the	DET
admet-843	103	23	biological	biological	ADJ
admet-843	103	24	actions	action	NOUN
admet-843	103	25	of	of	ADP
admet-843	103	26	pla	pla	NOUN
admet-843	103	27	:	:	PUNCT
admet-843	103	28	estrogenic	estrogenic	ADJ
admet-843	103	29	effects	effect	NOUN
admet-843	103	30	[	[	X
admet-843	103	31	13	13	NUM
admet-843	103	32	]	]	PUNCT
admet-843	103	33	,	,	PUNCT
admet-843	103	34	good	good	ADJ
admet-843	103	35	gastrointestinal	gastrointestinal	ADJ
admet-843	103	36	absorption	absorption	NOUN
admet-843	103	37	[	[	X
admet-843	103	38	32	32	NUM
admet-843	103	39	]	]	PUNCT
admet-843	103	40	,	,	PUNCT
admet-843	103	41	weak	weak	ADJ
admet-843	103	42	potential	potential	NOUN
admet-843	103	43	of	of	ADP
admet-843	103	44	p	p	NOUN
admet-843	103	45	-	-	PUNCT
admet-843	103	46	gp	gp	NOUN
admet-843	103	47	inhibition	inhibition	NOUN
admet-843	103	48	[	[	X
admet-843	103	49	33,34	33,34	NOUN
admet-843	103	50	]	]	PUNCT
admet-843	103	51	,	,	PUNCT
admet-843	103	52	binding	bind	VERB
admet-843	103	53	to	to	ADP
admet-843	103	54	human	human	ADJ
admet-843	103	55	serum	serum	NOUN
admet-843	103	56	albumin	albumin	NOUN
admet-843	104	1	[	[	X
admet-843	104	2	35,36	35,36	NUM
admet-843	104	3	]	]	PUNCT
admet-843	104	4	,	,	PUNCT
admet-843	104	5	penetration	penetration	NOUN
admet-843	104	6	of	of	ADP
admet-843	104	7	the	the	DET
admet-843	104	8	blood	blood	NOUN
admet-843	104	9	brain	brain	NOUN
admet-843	104	10	barrier	barrier	NOUN
admet-843	104	11	[	[	X
admet-843	104	12	37	37	NUM
admet-843	104	13	]	]	PUNCT
admet-843	104	14	.	.	PUNCT
admet-843	105	1	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	PROPN
admet-843	105	2	d.	d.	PROPN
admet-843	105	3	dascălu	dascălu	PROPN
admet-843	105	4	et	et	PROPN
admet-843	105	5	al	al	PROPN
admet-843	105	6	.	.	PROPN
admet-843	105	7	admet	admet	PROPN
admet-843	105	8	&	&	CCONJ
admet-843	105	9	dmpk	dmpk	PROPN
admet-843	105	10	8(4	8(4	NOUN
admet-843	105	11	)	)	PUNCT
admet-843	105	12	(	(	PUNCT
admet-843	105	13	2020	2020	NUM
admet-843	105	14	)	)	PUNCT
admet-843	105	15	425	425	NUM
admet-843	105	16	-	-	SYM
admet-843	105	17	436	436	NUM
admet-843	105	18	430	430	NUM
admet-843	105	19	table	table	NOUN
admet-843	105	20	3	3	NUM
admet-843	105	21	.	.	PUNCT
admet-843	106	1	admet	admet	PROPN
admet-843	106	2	properties	property	NOUN
admet-843	106	3	of	of	ADP
admet-843	106	4	olas	olas	PROPN
admet-843	106	5	:	:	PUNCT
admet-843	106	6	gi	gi	X
admet-843	106	7	–	–	PUNCT
admet-843	106	8	gastrointestinal	gastrointestinal	ADJ
admet-843	106	9	absorption	absorption	NOUN
admet-843	106	10	,	,	PUNCT
admet-843	106	11	bbbp	bbbp	NOUN
admet-843	106	12	–	–	PUNCT
admet-843	106	13	blood	blood	NOUN
admet-843	106	14	-	-	PUNCT
admet-843	106	15	brain	brain	NOUN
admet-843	106	16	barrier	barrier	NOUN
admet-843	106	17	penetration	penetration	NOUN
admet-843	106	18	,	,	PUNCT
admet-843	106	19	p	p	NOUN
admet-843	106	20	-	-	PUNCT
admet-843	106	21	gpssubstrate	gpssubstrate	NOUN
admet-843	106	22	of	of	ADP
admet-843	106	23	the	the	DET
admet-843	106	24	glycoprotein	glycoprotein	NOUN
admet-843	106	25	p	p	X
admet-843	106	26	,	,	PUNCT
admet-843	106	27	p	p	NOUN
admet-843	106	28	-	-	PUNCT
admet-843	106	29	gpiinhibitor	gpiinhibitor	NOUN
admet-843	106	30	of	of	ADP
admet-843	106	31	the	the	DET
admet-843	106	32	glycoprotein	glycoprotein	NOUN
admet-843	106	33	p	p	NOUN
admet-843	106	34	,	,	PUNCT
admet-843	106	35	ppb	ppb	NOUN
admet-843	106	36	–	–	PUNCT
admet-843	106	37	plasma	plasma	NOUN
admet-843	106	38	proteins	protein	NOUN
admet-843	106	39	binding	bind	VERB
admet-843	106	40	.	.	PUNCT
admet-843	107	1	the	the	DET
admet-843	107	2	numerical	numerical	ADJ
admet-843	107	3	values	value	NOUN
admet-843	107	4	in	in	ADP
admet-843	107	5	this	this	DET
admet-843	107	6	table	table	NOUN
admet-843	107	7	represent	represent	VERB
admet-843	107	8	the	the	DET
admet-843	107	9	probabilities	probability	NOUN
admet-843	107	10	that	that	PRON
admet-843	107	11	investigated	investigate	VERB
admet-843	107	12	oligomers	oligomer	NOUN
admet-843	107	13	have	have	VERB
admet-843	107	14	(	(	PUNCT
admet-843	107	15	positive	positive	ADJ
admet-843	107	16	values	value	NOUN
admet-843	107	17	)	)	PUNCT
admet-843	107	18	or	or	CCONJ
admet-843	107	19	have	have	VERB
admet-843	107	20	not	not	PART
admet-843	107	21	(	(	PUNCT
admet-843	107	22	negative	negative	ADJ
admet-843	107	23	values	value	NOUN
admet-843	107	24	)	)	PUNCT
admet-843	107	25	a	a	DET
admet-843	107	26	certain	certain	ADJ
admet-843	107	27	biological	biological	ADJ
admet-843	107	28	action	action	NOUN
admet-843	107	29	.	.	PUNCT
admet-843	108	1	the	the	DET
admet-843	108	2	notation	notation	NOUN
admet-843	108	3	”	"	PUNCT
admet-843	108	4	u	u	NOUN
admet-843	108	5	”	"	PUNCT
admet-843	108	6	refers	refer	VERB
admet-843	108	7	to	to	ADP
admet-843	108	8	the	the	DET
admet-843	108	9	number	number	NOUN
admet-843	108	10	of	of	ADP
admet-843	108	11	the	the	DET
admet-843	108	12	monomers	monomer	NOUN
admet-843	108	13	in	in	ADP
admet-843	108	14	the	the	DET
admet-843	108	15	oligomer	oligomer	NOUN
admet-843	108	16	.	.	PUNCT
admet-843	109	1	oligomer/	oligomer/	NUM
admet-843	109	2	biological	biological	ADJ
admet-843	109	3	action	action	NOUN
admet-843	109	4	and	and	CCONJ
admet-843	109	5	tool	tool	NOUN
admet-843	109	6	gi	gi	VERB
admet-843	109	7	bbbp	bbbp	PROPN
admet-843	109	8	p	p	PROPN
admet-843	109	9	-	-	PUNCT
admet-843	109	10	gps	gps	PROPN
admet-843	109	11	p	p	PROPN
admet-843	109	12	-	-	PUNCT
admet-843	109	13	gpi	gpi	PROPN
admet-843	109	14	ppb	ppb	PROPN
admet-843	109	15	admet	admet	PROPN
admet-843	109	16	sar	sar	PROPN
admet-843	109	17	swiss	swiss	PROPN
admet-843	109	18	adme	adme	PROPN
admet-843	109	19	admet	admet	PROPN
admet-843	109	20	sar	sar	PROPN
admet-843	109	21	swiss	swiss	PROPN
admet-843	109	22	adme	adme	PROPN
admet-843	109	23	admet	admet	PROPN
admet-843	109	24	sar	sar	PROPN
admet-843	109	25	admet	admet	PROPN
admet-843	109	26	sar	sar	PROPN
admet-843	109	27	swiss	swiss	PROPN
admet-843	109	28	adme	adme	PROPN
admet-843	109	29	admet	admet	PROPN
admet-843	109	30	sar	sar	PROPN
admet-843	109	31	ola	ola	PROPN
admet-843	109	32	1u	1u	PROPN
admet-843	109	33	0.86	0.86	NUM
admet-843	109	34	high	high	ADJ
admet-843	109	35	0.95	0.95	NUM
admet-843	110	1	no	no	DET
admet-843	110	2	-1.00	-1.00	NUM
admet-843	110	3	-0.99	-0.99	NOUN
admet-843	110	4	no	no	DET
admet-843	110	5	0.63	0.63	NUM
admet-843	110	6	ola	ola	PROPN
admet-843	110	7	2u	2u	PROPN
admet-843	110	8	0.90	0.90	NUM
admet-843	110	9	high	high	ADJ
admet-843	110	10	0.98	0.98	NUM
admet-843	110	11	no	no	DET
admet-843	110	12	-0.99	-0.99	NOUN
admet-843	110	13	-0.98	-0.98	NOUN
admet-843	111	1	no	no	INTJ
admet-843	111	2	0.63	0.63	NUM
admet-843	111	3	ola	ola	PROPN
admet-843	111	4	3u	3u	NUM
admet-843	111	5	0.90	0.90	NUM
admet-843	111	6	high	high	ADJ
admet-843	111	7	0.98	0.98	NUM
admet-843	111	8	no	no	DET
admet-843	111	9	-0.99	-0.99	NOUN
admet-843	111	10	-0.94	-0.94	NOUN
admet-843	111	11	no	no	DET
admet-843	111	12	0.58	0.58	NUM
admet-843	112	1	ola	ola	PROPN
admet-843	112	2	4u	4u	NOUN
admet-843	112	3	0.90	0.90	NUM
admet-843	112	4	low	low	ADV
admet-843	112	5	0.98	0.98	NUM
admet-843	112	6	no	no	DET
admet-843	112	7	-0.99	-0.99	NOUN
admet-843	112	8	-0.85	-0.85	NOUN
admet-843	112	9	no	no	DET
admet-843	112	10	0.55	0.55	NUM
admet-843	112	11	ola	ola	PROPN
admet-843	112	12	5u	5u	NUM
admet-843	112	13	0.90	0.90	NUM
admet-843	112	14	low	low	ADJ
admet-843	112	15	0.98	0.98	NUM
admet-843	112	16	no	no	DET
admet-843	112	17	-0.99	-0.99	NOUN
admet-843	112	18	-0.66	-0.66	NUM
admet-843	113	1	no	no	DET
admet-843	113	2	0.53	0.53	NOUN
admet-843	113	3	ola	ola	PROPN
admet-843	113	4	6u	6u	NUM
admet-843	113	5	0.90	0.90	NUM
admet-843	113	6	low	low	ADJ
admet-843	113	7	0.98	0.98	NUM
admet-843	113	8	no	no	DET
admet-843	113	9	-0.99	-0.99	NOUN
admet-843	113	10	-0.49	-0.49	NOUN
admet-843	113	11	no	no	DET
admet-843	113	12	0.52	0.52	NUM
admet-843	113	13	ola	ola	PROPN
admet-843	113	14	7u	7u	NUM
admet-843	113	15	0.90	0.90	NUM
admet-843	113	16	low	low	ADJ
admet-843	113	17	0.98	0.98	NUM
admet-843	113	18	no	no	DET
admet-843	113	19	-0.99	-0.99	NOUN
admet-843	113	20	0.62	0.62	NUM
admet-843	113	21	no	no	DET
admet-843	113	22	0.52	0.52	NUM
admet-843	113	23	ola	ola	PROPN
admet-843	113	24	8u	8u	PROPN
admet-843	113	25	0.90	0.90	NUM
admet-843	113	26	low	low	ADJ
admet-843	113	27	0.98	0.98	NUM
admet-843	113	28	no	no	DET
admet-843	113	29	-0.99	-0.99	NOUN
admet-843	113	30	0.68	0.68	NUM
admet-843	114	1	no	no	DET
admet-843	114	2	0.51	0.51	NUM
admet-843	114	3	ola	ola	PROPN
admet-843	114	4	10u	10u	NOUN
admet-843	114	5	0.90	0.90	NUM
admet-843	114	6	low	low	ADJ
admet-843	114	7	0.98	0.98	NUM
admet-843	114	8	no	no	DET
admet-843	114	9	-0.99	-0.99	NOUN
admet-843	114	10	0.73	0.73	NUM
admet-843	114	11	no	no	DET
admet-843	114	12	0.50	0.50	NUM
admet-843	114	13	ola	ola	PROPN
admet-843	114	14	12u	12u	PROPN
admet-843	114	15	0.90	0.90	NUM
admet-843	114	16	low	low	ADJ
admet-843	114	17	0.98	0.98	NUM
admet-843	114	18	no	no	DET
admet-843	114	19	-0.99	-0.99	NOUN
admet-843	114	20	0.74	0.74	NUM
admet-843	115	1	no	no	DET
admet-843	115	2	0.50	0.50	NUM
admet-843	115	3	ola	ola	PROPN
admet-843	115	4	14u	14u	NUM
admet-843	115	5	0.90	0.90	NUM
admet-843	115	6	low	low	ADJ
admet-843	115	7	0.98	0.98	NUM
admet-843	115	8	no	no	DET
admet-843	115	9	-0.99	-0.99	NOUN
admet-843	115	10	0.74	0.74	NUM
admet-843	115	11	no	no	INTJ
admet-843	115	12	0.49	0.49	NUM
admet-843	115	13	ola	ola	PROPN
admet-843	115	14	16uola	16uola	PROPN
admet-843	115	15	40u	40u	PROPN
admet-843	115	16	0.90	0.90	NUM
admet-843	115	17	low	low	ADJ
admet-843	115	18	0.98	0.98	NUM
admet-843	115	19	no	no	DET
admet-843	115	20	-0.99	-0.99	NOUN
admet-843	115	21	0.74	0.74	NUM
admet-843	115	22	no	no	DET
admet-843	115	23	0.49	0.49	NUM
admet-843	115	24	data	datum	NOUN
admet-843	115	25	presented	present	VERB
admet-843	115	26	in	in	ADP
admet-843	115	27	table	table	NOUN
admet-843	115	28	3	3	NUM
admet-843	115	29	illustrate	illustrate	VERB
admet-843	115	30	that	that	SCONJ
admet-843	115	31	pla	pla	PROPN
admet-843	115	32	short	short	ADJ
admet-843	115	33	oligomers	oligomer	NOUN
admet-843	115	34	are	be	AUX
admet-843	115	35	predicted	predict	VERB
admet-843	115	36	to	to	PART
admet-843	115	37	have	have	VERB
admet-843	115	38	good	good	ADJ
admet-843	115	39	gastrointestinal	gastrointestinal	ADJ
admet-843	115	40	absorption	absorption	NOUN
admet-843	115	41	and	and	CCONJ
admet-843	115	42	they	they	PRON
admet-843	115	43	are	be	AUX
admet-843	115	44	not	not	PART
admet-843	115	45	considered	consider	VERB
admet-843	115	46	substrates	substrate	NOUN
admet-843	115	47	of	of	ADP
admet-843	115	48	the	the	DET
admet-843	115	49	p	p	NOUN
admet-843	115	50	-	-	PUNCT
admet-843	115	51	glycoprotein	glycoprotein	NOUN
admet-843	115	52	.	.	PUNCT
admet-843	116	1	the	the	DET
admet-843	116	2	good	good	ADJ
admet-843	116	3	gastrointestinal	gastrointestinal	ADJ
admet-843	116	4	absorption	absorption	NOUN
admet-843	116	5	of	of	ADP
admet-843	116	6	pla	pla	PROPN
admet-843	116	7	has	have	AUX
admet-843	116	8	been	be	AUX
admet-843	116	9	also	also	ADV
admet-843	116	10	observed	observe	VERB
admet-843	116	11	by	by	ADP
admet-843	116	12	fernandez	fernandez	PROPN
admet-843	116	13	et	et	PROPN
admet-843	116	14	al	al	PROPN
admet-843	116	15	(	(	PUNCT
admet-843	116	16	2017	2017	NUM
admet-843	116	17	)	)	PUNCT
admet-843	117	1	[	[	X
admet-843	117	2	32	32	NUM
admet-843	117	3	]	]	PUNCT
admet-843	117	4	by	by	ADP
admet-843	117	5	modeling	model	VERB
admet-843	117	6	the	the	DET
admet-843	117	7	pla	pla	NOUN
admet-843	117	8	nanoparticles	nanoparticle	VERB
admet-843	117	9	absorption	absorption	NOUN
admet-843	117	10	under	under	ADP
admet-843	117	11	gastrointestinal	gastrointestinal	ADJ
admet-843	117	12	conditions	condition	NOUN
admet-843	117	13	.	.	PUNCT
admet-843	118	1	their	their	PRON
admet-843	118	2	study	study	NOUN
admet-843	118	3	revealed	reveal	VERB
admet-843	118	4	that	that	SCONJ
admet-843	118	5	the	the	DET
admet-843	118	6	intestinal	intestinal	ADJ
admet-843	118	7	absorption	absorption	NOUN
admet-843	118	8	of	of	ADP
admet-843	118	9	grape	grape	NOUN
admet-843	118	10	seed	seed	NOUN
admet-843	118	11	and	and	CCONJ
admet-843	118	12	skin	skin	NOUN
admet-843	118	13	extracts	extract	NOUN
admet-843	118	14	encapsulated	encapsulate	VERB
admet-843	118	15	in	in	ADP
admet-843	118	16	pla	pla	NOUN
admet-843	118	17	nanoparticles	nanoparticle	NOUN
admet-843	118	18	was	be	AUX
admet-843	118	19	significantly	significantly	ADV
admet-843	118	20	increased	increase	VERB
admet-843	118	21	.	.	PUNCT
admet-843	119	1	admetsar	admetsar	ADJ
admet-843	119	2	tool	tool	NOUN
admet-843	119	3	reveals	reveal	VERB
admet-843	119	4	that	that	SCONJ
admet-843	119	5	oligomers	oligomer	NOUN
admet-843	119	6	containing	contain	VERB
admet-843	119	7	between	between	ADP
admet-843	119	8	7	7	NUM
admet-843	119	9	(	(	PUNCT
admet-843	119	10	mw	mw	X
admet-843	119	11	=	=	SYM
admet-843	119	12	523	523	NUM
admet-843	119	13	da	da	NOUN
admet-843	119	14	)	)	PUNCT
admet-843	119	15	and	and	CCONJ
admet-843	119	16	40	40	NUM
admet-843	119	17	(	(	PUNCT
admet-843	119	18	mw	mw	X
admet-843	119	19	=	=	SYM
admet-843	119	20	2900	2900	NUM
admet-843	119	21	da	da	NOUN
admet-843	119	22	)	)	PUNCT
admet-843	119	23	lactic	lactic	ADJ
admet-843	119	24	acid	acid	NOUN
admet-843	119	25	units	unit	NOUN
admet-843	119	26	illustrate	illustrate	VERB
admet-843	119	27	a	a	DET
admet-843	119	28	mean	mean	ADJ
admet-843	119	29	probability	probability	NOUN
admet-843	119	30	to	to	PART
admet-843	119	31	be	be	AUX
admet-843	119	32	inhibitors	inhibitor	NOUN
admet-843	119	33	of	of	ADP
admet-843	119	34	p	p	NOUN
admet-843	119	35	-	-	PUNCT
admet-843	119	36	glycoprotein	glycoprotein	NOUN
admet-843	119	37	,	,	PUNCT
admet-843	119	38	this	this	DET
admet-843	119	39	probability	probability	NOUN
admet-843	119	40	increases	increase	VERB
admet-843	119	41	with	with	ADP
admet-843	119	42	the	the	DET
admet-843	119	43	chain	chain	NOUN
admet-843	119	44	length	length	NOUN
admet-843	119	45	.	.	PUNCT
admet-843	120	1	this	this	DET
admet-843	120	2	prediction	prediction	NOUN
admet-843	120	3	is	be	AUX
admet-843	120	4	in	in	ADP
admet-843	120	5	good	good	ADJ
admet-843	120	6	agreement	agreement	NOUN
admet-843	120	7	with	with	ADP
admet-843	120	8	published	publish	VERB
admet-843	120	9	data	datum	NOUN
admet-843	120	10	by	by	ADP
admet-843	120	11	li	li	PROPN
admet-843	120	12	and	and	CCONJ
admet-843	120	13	his	his	PRON
admet-843	120	14	co	co	NOUN
admet-843	120	15	-	-	NOUN
admet-843	120	16	workers	worker	NOUN
admet-843	120	17	(	(	PUNCT
admet-843	120	18	2013	2013	NUM
admet-843	120	19	)	)	PUNCT
admet-843	121	1	[	[	X
admet-843	121	2	33	33	NUM
admet-843	121	3	]	]	PUNCT
admet-843	121	4	.	.	PUNCT
admet-843	122	1	the	the	DET
admet-843	122	2	study	study	NOUN
admet-843	122	3	of	of	ADP
admet-843	122	4	li	li	PROPN
admet-843	122	5	and	and	CCONJ
admet-843	122	6	co	co	NOUN
admet-843	122	7	-	-	NOUN
admet-843	122	8	workers	worker	NOUN
admet-843	122	9	revealed	reveal	VERB
admet-843	122	10	that	that	SCONJ
admet-843	122	11	copolymers	copolymer	NOUN
admet-843	122	12	of	of	ADP
admet-843	122	13	mpeg	mpeg	NOUN
admet-843	122	14	-	-	PUNCT
admet-843	122	15	pla	pla	NOUN
admet-843	122	16	could	could	AUX
admet-843	122	17	inhibit	inhibit	VERB
admet-843	122	18	p	p	NOUN
admet-843	122	19	-	-	PUNCT
admet-843	122	20	gp	gp	NOUN
admet-843	122	21	mediated	mediate	VERB
admet-843	122	22	efflux	efflux	NOUN
admet-843	122	23	and	and	CCONJ
admet-843	122	24	that	that	DET
admet-843	122	25	concentration	concentration	NOUN
admet-843	122	26	played	play	VERB
admet-843	122	27	a	a	DET
admet-843	122	28	major	major	ADJ
admet-843	122	29	role	role	NOUN
admet-843	122	30	in	in	ADP
admet-843	122	31	the	the	DET
admet-843	122	32	p	p	NOUN
admet-843	122	33	-	-	PUNCT
admet-843	122	34	gp	gp	NOUN
admet-843	122	35	inhibition	inhibition	NOUN
admet-843	122	36	activity	activity	NOUN
admet-843	122	37	.	.	PUNCT
admet-843	123	1	polyethylene	polyethylene	NOUN
admet-843	123	2	glycol	glycol	NOUN
admet-843	123	3	(	(	PUNCT
admet-843	123	4	peg	peg	NOUN
admet-843	123	5	)	)	PUNCT
admet-843	123	6	is	be	AUX
admet-843	123	7	a	a	DET
admet-843	123	8	known	know	VERB
admet-843	123	9	p	p	NOUN
admet-843	123	10	-	-	PUNCT
admet-843	123	11	gp	gp	NOUN
admet-843	123	12	inhibitor	inhibitor	NOUN
admet-843	124	1	[	[	X
admet-843	124	2	34	34	NUM
admet-843	124	3	]	]	PUNCT
admet-843	124	4	and	and	CCONJ
admet-843	124	5	the	the	DET
admet-843	124	6	fact	fact	NOUN
admet-843	124	7	that	that	SCONJ
admet-843	124	8	the	the	DET
admet-843	124	9	inhibitory	inhibitory	ADJ
admet-843	124	10	effect	effect	NOUN
admet-843	124	11	on	on	ADP
admet-843	124	12	p	p	NOUN
admet-843	124	13	-	-	PUNCT
admet-843	124	14	gp	gp	NOUN
admet-843	124	15	efflux	efflux	NOUN
admet-843	124	16	of	of	ADP
admet-843	124	17	the	the	DET
admet-843	124	18	copolymers	copolymer	NOUN
admet-843	124	19	mpeg	mpeg	NOUN
admet-843	124	20	-	-	PUNCT
admet-843	124	21	pla	pla	NOUN
admet-843	124	22	having	have	VERB
admet-843	124	23	the	the	DET
admet-843	124	24	same	same	ADJ
admet-843	124	25	peg	peg	NOUN
admet-843	124	26	chain	chain	NOUN
admet-843	124	27	length	length	NOUN
admet-843	124	28	is	be	AUX
admet-843	124	29	depended	depend	VERB
admet-843	124	30	on	on	ADP
admet-843	124	31	the	the	DET
admet-843	124	32	pla	pla	NOUN
admet-843	124	33	chain	chain	NOUN
admet-843	124	34	length	length	NOUN
admet-843	124	35	,	,	PUNCT
admet-843	124	36	underlines	underline	VERB
admet-843	124	37	that	that	PRON
admet-843	124	38	pla	pla	PROPN
admet-843	124	39	also	also	ADV
admet-843	124	40	has	have	VERB
admet-843	124	41	an	an	DET
admet-843	124	42	inhibitory	inhibitory	ADJ
admet-843	124	43	effect	effect	NOUN
admet-843	124	44	on	on	ADP
admet-843	124	45	p	p	NOUN
admet-843	124	46	-	-	PUNCT
admet-843	124	47	gp	gp	NOUN
admet-843	124	48	activity	activity	NOUN
admet-843	124	49	.	.	PUNCT
admet-843	125	1	the	the	DET
admet-843	125	2	copolymer	copolymer	NOUN
admet-843	125	3	with	with	ADP
admet-843	125	4	pla	pla	PROPN
admet-843	125	5	chain	chain	NOUN
admet-843	125	6	length	length	NOUN
admet-843	125	7	of	of	ADP
admet-843	125	8	4802	4802	NUM
admet-843	125	9	da	da	PROPN
admet-843	125	10	was	be	AUX
admet-843	125	11	the	the	DET
admet-843	125	12	most	most	ADV
admet-843	125	13	efficient	efficient	ADJ
admet-843	125	14	pgp	pgp	NOUN
admet-843	125	15	activity	activity	NOUN
admet-843	125	16	inhibitor	inhibitor	NOUN
admet-843	125	17	and	and	CCONJ
admet-843	125	18	copolymers	copolymer	NOUN
admet-843	125	19	with	with	ADP
admet-843	125	20	longer	long	ADJ
admet-843	125	21	or	or	CCONJ
admet-843	125	22	shorter	short	ADJ
admet-843	125	23	pla	pla	NOUN
admet-843	125	24	chain	chain	NOUN
admet-843	125	25	lengths	length	NOUN
admet-843	125	26	,	,	PUNCT
admet-843	125	27	gradually	gradually	ADV
admet-843	125	28	showed	show	VERB
admet-843	125	29	weaker	weak	ADJ
admet-843	125	30	inhibitory	inhibitory	ADJ
admet-843	125	31	potential	potential	NOUN
admet-843	125	32	on	on	ADP
admet-843	125	33	p	p	NOUN
admet-843	125	34	-	-	PUNCT
admet-843	125	35	gp	gp	NOUN
admet-843	125	36	function	function	NOUN
admet-843	125	37	[	[	X
admet-843	125	38	33	33	NUM
admet-843	125	39	]	]	PUNCT
admet-843	125	40	.	.	PUNCT
admet-843	126	1	there	there	PRON
admet-843	126	2	is	be	VERB
admet-843	126	3	a	a	DET
admet-843	126	4	disparity	disparity	NOUN
admet-843	126	5	between	between	ADP
admet-843	126	6	the	the	DET
admet-843	126	7	predictions	prediction	NOUN
admet-843	126	8	made	make	VERB
admet-843	126	9	by	by	ADP
admet-843	126	10	the	the	DET
admet-843	126	11	two	two	NUM
admet-843	126	12	computational	computational	ADJ
admet-843	126	13	tools	tool	NOUN
admet-843	126	14	concerning	concern	VERB
admet-843	126	15	the	the	DET
admet-843	126	16	ability	ability	NOUN
admet-843	126	17	of	of	ADP
admet-843	126	18	olas	olas	PROPN
admet-843	126	19	to	to	PART
admet-843	126	20	penetrate	penetrate	VERB
admet-843	126	21	the	the	DET
admet-843	126	22	blood	blood	NOUN
admet-843	126	23	-	-	PUNCT
admet-843	126	24	brain	brain	NOUN
admet-843	126	25	barrier	barrier	NOUN
admet-843	126	26	,	,	PUNCT
admet-843	126	27	admetsar	admetsar	ADJ
admet-843	126	28	predicts	predict	VERB
admet-843	126	29	high	high	ADJ
admet-843	126	30	probabilities	probability	NOUN
admet-843	126	31	of	of	ADP
admet-843	126	32	penetration	penetration	NOUN
admet-843	126	33	of	of	ADP
admet-843	126	34	bloodbrain	bloodbrain	NOUN
admet-843	126	35	barrier	barrier	NOUN
admet-843	126	36	and	and	CCONJ
admet-843	126	37	swissadme	swissadme	NOUN
admet-843	126	38	outcomes	outcome	NOUN
admet-843	126	39	reveal	reveal	VERB
admet-843	126	40	that	that	SCONJ
admet-843	126	41	olas	ola	NOUN
admet-843	126	42	are	be	AUX
admet-843	126	43	not	not	PART
admet-843	126	44	able	able	ADJ
admet-843	126	45	to	to	PART
admet-843	126	46	penetrate	penetrate	VERB
admet-843	126	47	this	this	DET
admet-843	126	48	barrier	barrier	NOUN
admet-843	126	49	.	.	PUNCT
admet-843	127	1	swissadme	swissadme	PROPN
admet-843	127	2	tool	tool	PROPN
admet-843	127	3	uses	use	VERB
admet-843	127	4	for	for	ADP
admet-843	127	5	computing	compute	VERB
admet-843	127	6	blood	blood	NOUN
admet-843	127	7	-	-	PUNCT
admet-843	127	8	brain	brain	NOUN
admet-843	127	9	–	–	PUNCT
admet-843	127	10	barrier	barrier	NOUN
admet-843	127	11	permeation	permeation	NOUN
admet-843	127	12	a	a	DET
admet-843	127	13	model	model	NOUN
admet-843	127	14	containing	contain	VERB
admet-843	127	15	260	260	NUM
admet-843	127	16	molecules	molecule	NOUN
admet-843	127	17	(	(	PUNCT
admet-843	127	18	156	156	NUM
admet-843	127	19	permeant	permeant	ADJ
admet-843	127	20	and	and	CCONJ
admet-843	127	21	104	104	NUM
admet-843	127	22	non	non	ADJ
admet-843	127	23	-	-	ADJ
admet-843	127	24	permeant	permeant	ADJ
admet-843	127	25	)	)	PUNCT
admet-843	127	26	with	with	ADP
admet-843	127	27	reliable	reliable	ADJ
admet-843	127	28	measurements	measurement	NOUN
admet-843	127	29	of	of	ADP
admet-843	127	30	blood	blood	NOUN
admet-843	127	31	–	–	PUNCT
admet-843	127	32	brain	brain	NOUN
admet-843	127	33	partition	partition	NOUN
admet-843	127	34	and	and	CCONJ
admet-843	127	35	has	have	VERB
admet-843	127	36	a	a	DET
admet-843	127	37	classification	classification	NOUN
admet-843	127	38	accuracy	accuracy	NOUN
admet-843	127	39	of	of	ADP
admet-843	127	40	90	90	NUM
admet-843	127	41	%	%	NOUN
admet-843	128	1	[	[	X
admet-843	128	2	38	38	NUM
admet-843	128	3	]	]	PUNCT
admet-843	128	4	.	.	PUNCT
admet-843	129	1	admetsar	admetsar	ADJ
admet-843	129	2	tool	tool	NOUN
admet-843	129	3	uses	use	VERB
admet-843	129	4	for	for	ADP
admet-843	129	5	predicting	predict	VERB
admet-843	129	6	blood	blood	NOUN
admet-843	129	7	barrier	barrier	NOUN
admet-843	129	8	penetration	penetration	NOUN
admet-843	129	9	a	a	DET
admet-843	129	10	binary	binary	ADJ
admet-843	129	11	model	model	NOUN
admet-843	129	12	containing	contain	VERB
admet-843	129	13	a	a	DET
admet-843	129	14	higher	high	ADJ
admet-843	129	15	number	number	NOUN
admet-843	129	16	of	of	ADP
admet-843	129	17	compounds	compound	NOUN
admet-843	129	18	(	(	PUNCT
admet-843	129	19	1839	1839	NUM
admet-843	129	20	with	with	ADP
admet-843	129	21	1438	1438	NUM
admet-843	129	22	permeant	permeant	ADJ
admet-843	129	23	and	and	CCONJ
admet-843	129	24	401	401	NUM
admet-843	129	25	no	no	ADV
admet-843	129	26	-	-	PUNCT
admet-843	129	27	permeant	permeant	ADJ
admet-843	129	28	)	)	PUNCT
admet-843	129	29	,	,	PUNCT
admet-843	129	30	has	have	VERB
admet-843	129	31	an	an	DET
admet-843	129	32	accuracy	accuracy	NOUN
admet-843	129	33	of	of	ADP
admet-843	129	34	prediction	prediction	NOUN
admet-843	129	35	of	of	ADP
admet-843	129	36	90.7	90.7	NUM
admet-843	129	37	%	%	NOUN
admet-843	129	38	and	and	CCONJ
admet-843	129	39	a	a	DET
admet-843	129	40	specificity	specificity	NOUN
admet-843	129	41	of	of	ADP
admet-843	129	42	86.2	86.2	NUM
admet-843	129	43	%	%	NOUN
admet-843	130	1	[	[	X
admet-843	130	2	18	18	NUM
admet-843	130	3	]	]	PUNCT
admet-843	130	4	.	.	PUNCT
admet-843	131	1	the	the	DET
admet-843	131	2	in	in	ADP
admet-843	131	3	vivo	vivo	ADJ
admet-843	131	4	experiments	experiment	NOUN
admet-843	131	5	proved	prove	VERB
admet-843	131	6	that	that	SCONJ
admet-843	131	7	the	the	DET
admet-843	131	8	pla	pla	NOUN
admet-843	131	9	nanoparticles	nanoparticle	NOUN
admet-843	131	10	are	be	AUX
admet-843	131	11	able	able	ADJ
admet-843	131	12	to	to	PART
admet-843	131	13	penetrate	penetrate	VERB
admet-843	131	14	bbb	bbb	NOUN
admet-843	131	15	using	use	VERB
admet-843	131	16	transcytosis	transcytosis	NOUN
admet-843	131	17	by	by	ADP
admet-843	131	18	microvascular	microvascular	ADJ
admet-843	131	19	endothelial	endothelial	ADJ
admet-843	131	20	cells	cell	NOUN
admet-843	131	21	[	[	X
admet-843	131	22	34	34	NUM
admet-843	131	23	]	]	PUNCT
admet-843	131	24	.	.	PUNCT
admet-843	132	1	admetsar2.0	admetsar2.0	PROPN
admet-843	132	2	tool	tool	NOUN
admet-843	132	3	seems	seem	VERB
admet-843	132	4	to	to	PART
admet-843	132	5	better	well	ADV
admet-843	132	6	predict	predict	VERB
admet-843	132	7	the	the	DET
admet-843	132	8	ability	ability	NOUN
admet-843	132	9	of	of	ADP
admet-843	132	10	the	the	DET
admet-843	132	11	blood	blood	NOUN
admet-843	132	12	barrier	barrier	NOUN
admet-843	132	13	permeation	permeation	NOUN
admet-843	132	14	for	for	ADP
admet-843	132	15	olas	olas	PROPN
admet-843	132	16	.	.	PUNCT
admet-843	133	1	the	the	DET
admet-843	133	2	admet	admet	PROPN
admet-843	133	3	&	&	CCONJ
admet-843	133	4	dmpk	dmpk	PROPN
admet-843	133	5	8(4	8(4	NOUN
admet-843	133	6	)	)	PUNCT
admet-843	133	7	(	(	PUNCT
admet-843	133	8	2020	2020	NUM
admet-843	133	9	)	)	PUNCT
admet-843	133	10	425	425	NUM
admet-843	133	11	-	-	SYM
admet-843	133	12	436	436	NUM
admet-843	133	13	admet	admet	NOUN
admet-843	133	14	profiles	profile	NOUN
admet-843	133	15	of	of	ADP
admet-843	133	16	oligomers	oligomer	NOUN
admet-843	133	17	of	of	ADP
admet-843	133	18	lactic	lactic	ADJ
admet-843	133	19	acid	acid	NOUN
admet-843	133	20	doi	doi	NOUN
admet-843	133	21	:	:	PUNCT
admet-843	133	22	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	NOUN
admet-843	133	23	431	431	NUM
admet-843	133	24	disagreement	disagreement	NOUN
admet-843	133	25	of	of	ADP
admet-843	133	26	the	the	DET
admet-843	133	27	predictions	prediction	NOUN
admet-843	133	28	made	make	VERB
admet-843	133	29	by	by	ADP
admet-843	133	30	the	the	DET
admet-843	133	31	two	two	NUM
admet-843	133	32	computational	computational	ADJ
admet-843	133	33	tolls	toll	NOUN
admet-843	133	34	also	also	ADV
admet-843	133	35	underlines	underline	VERB
admet-843	133	36	the	the	DET
admet-843	133	37	limitations	limitation	NOUN
admet-843	133	38	of	of	ADP
admet-843	133	39	the	the	DET
admet-843	133	40	computational	computational	ADJ
admet-843	133	41	evaluation	evaluation	NOUN
admet-843	133	42	of	of	ADP
admet-843	133	43	the	the	DET
admet-843	133	44	biological	biological	ADJ
admet-843	133	45	effects	effect	NOUN
admet-843	133	46	of	of	ADP
admet-843	133	47	chemicals	chemical	NOUN
admet-843	133	48	and	and	CCONJ
admet-843	133	49	the	the	DET
admet-843	133	50	necessity	necessity	NOUN
admet-843	133	51	to	to	PART
admet-843	133	52	perform	perform	VERB
admet-843	133	53	experimental	experimental	ADJ
admet-843	133	54	studies	study	NOUN
admet-843	133	55	to	to	PART
admet-843	133	56	assess	assess	VERB
admet-843	133	57	this	this	DET
admet-843	133	58	property	property	NOUN
admet-843	133	59	for	for	ADP
admet-843	133	60	olas	olas	PROPN
admet-843	133	61	.	.	PUNCT
admet-843	134	1	data	datum	NOUN
admet-843	134	2	from	from	ADP
admet-843	134	3	table	table	NOUN
admet-843	134	4	3	3	NUM
admet-843	134	5	also	also	ADV
admet-843	134	6	illustrate	illustrate	VERB
admet-843	134	7	that	that	SCONJ
admet-843	134	8	the	the	DET
admet-843	134	9	probability	probability	NOUN
admet-843	134	10	of	of	ADP
admet-843	134	11	olas	olas	PROPN
admet-843	134	12	to	to	PART
admet-843	134	13	bind	bind	VERB
admet-843	134	14	to	to	ADP
admet-843	134	15	plasma	plasma	NOUN
admet-843	134	16	proteins	protein	NOUN
admet-843	134	17	is	be	AUX
admet-843	134	18	reduced	reduce	VERB
admet-843	134	19	and	and	CCONJ
admet-843	134	20	it	it	PRON
admet-843	134	21	decreases	decrease	VERB
admet-843	134	22	with	with	ADP
admet-843	134	23	increasing	increase	VERB
admet-843	134	24	the	the	DET
admet-843	134	25	chain	chain	NOUN
admet-843	134	26	length	length	NOUN
admet-843	134	27	.	.	PUNCT
admet-843	135	1	earlier	early	ADJ
admet-843	135	2	studies	study	NOUN
admet-843	135	3	revealed	reveal	VERB
admet-843	135	4	that	that	SCONJ
admet-843	135	5	lactic	lactic	ADJ
admet-843	135	6	acid	acid	NOUN
admet-843	135	7	is	be	AUX
admet-843	135	8	able	able	ADJ
admet-843	135	9	to	to	PART
admet-843	135	10	bind	bind	VERB
admet-843	135	11	to	to	PART
admet-843	135	12	bovine	bovine	VERB
admet-843	135	13	serum	serum	NOUN
admet-843	135	14	albumin	albumin	NOUN
admet-843	136	1	[	[	X
admet-843	136	2	35	35	NUM
admet-843	136	3	]	]	PUNCT
admet-843	136	4	and	and	CCONJ
admet-843	136	5	adsorption	adsorption	NOUN
admet-843	136	6	/	/	SYM
admet-843	136	7	desorption	desorption	NOUN
admet-843	136	8	of	of	ADP
admet-843	136	9	human	human	ADJ
admet-843	136	10	serum	serum	NOUN
admet-843	136	11	albumin	albumin	NOUN
admet-843	136	12	at	at	ADP
admet-843	136	13	the	the	DET
admet-843	136	14	surface	surface	NOUN
admet-843	136	15	of	of	ADP
admet-843	136	16	pla	pla	PROPN
admet-843	136	17	nanoparticles	nanoparticle	NOUN
admet-843	136	18	(	(	PUNCT
admet-843	136	19	nps	nps	PROPN
admet-843	136	20	)	)	PUNCT
admet-843	136	21	that	that	PRON
admet-843	136	22	decreased	decrease	VERB
admet-843	136	23	with	with	ADP
admet-843	136	24	increasing	increase	VERB
admet-843	136	25	the	the	DET
admet-843	136	26	diameter	diameter	NOUN
admet-843	136	27	of	of	ADP
admet-843	136	28	nps	nps	PROPN
admet-843	136	29	has	have	AUX
admet-843	136	30	been	be	AUX
admet-843	136	31	observed	observe	VERB
admet-843	136	32	[	[	X
admet-843	136	33	36	36	NUM
admet-843	136	34	]	]	PUNCT
admet-843	136	35	.	.	PUNCT
admet-843	137	1	table	table	NOUN
admet-843	137	2	4	4	NUM
admet-843	137	3	.	.	PUNCT
admet-843	137	4	probabilities	probability	NOUN
admet-843	137	5	that	that	PRON
admet-843	137	6	olas	ola	NOUN
admet-843	137	7	are	be	AUX
admet-843	137	8	substrates	substrate	NOUN
admet-843	137	9	(	(	PUNCT
admet-843	137	10	s	s	NOUN
admet-843	137	11	)	)	PUNCT
admet-843	137	12	and	and	CCONJ
admet-843	137	13	inhibitors	inhibitor	NOUN
admet-843	137	14	(	(	PUNCT
admet-843	137	15	i	i	NOUN
admet-843	137	16	)	)	PUNCT
admet-843	137	17	of	of	ADP
admet-843	137	18	the	the	DET
admet-843	137	19	human	human	ADJ
admet-843	137	20	cytochromes	cytochrome	NOUN
admet-843	137	21	(	(	PUNCT
admet-843	137	22	cyp	cyp	ADJ
admet-843	137	23	)	)	PUNCT
admet-843	137	24	involved	involve	VERB
admet-843	137	25	in	in	ADP
admet-843	137	26	the	the	DET
admet-843	137	27	metabolism	metabolism	NOUN
admet-843	137	28	of	of	ADP
admet-843	137	29	xenobiotics	xenobiotics	PROPN
admet-843	137	30	.	.	PUNCT
admet-843	138	1	the	the	DET
admet-843	138	2	values	value	NOUN
admet-843	138	3	in	in	ADP
admet-843	138	4	this	this	DET
admet-843	138	5	table	table	NOUN
admet-843	138	6	represent	represent	VERB
admet-843	138	7	the	the	DET
admet-843	138	8	probabilities	probability	NOUN
admet-843	138	9	that	that	PRON
admet-843	138	10	investigated	investigate	VERB
admet-843	138	11	oligomers	oligomer	NOUN
admet-843	138	12	are	be	AUX
admet-843	138	13	(	(	PUNCT
admet-843	138	14	positive	positive	ADJ
admet-843	138	15	values	value	NOUN
admet-843	138	16	)	)	PUNCT
admet-843	138	17	or	or	CCONJ
admet-843	138	18	are	be	AUX
admet-843	138	19	not	not	PART
admet-843	138	20	(	(	PUNCT
admet-843	138	21	negative	negative	ADJ
admet-843	138	22	values	value	NOUN
admet-843	138	23	)	)	PUNCT
admet-843	138	24	substrates	substrate	NOUN
admet-843	138	25	or	or	CCONJ
admet-843	138	26	inhibitors	inhibitor	NOUN
admet-843	138	27	of	of	ADP
admet-843	138	28	cytochromes	cytochrome	NOUN
admet-843	138	29	.	.	PUNCT
admet-843	139	1	the	the	DET
admet-843	139	2	notation	notation	NOUN
admet-843	139	3	”	"	PUNCT
admet-843	139	4	u	u	NOUN
admet-843	139	5	”	"	PUNCT
admet-843	139	6	refers	refer	VERB
admet-843	139	7	to	to	ADP
admet-843	139	8	the	the	DET
admet-843	139	9	number	number	NOUN
admet-843	139	10	of	of	ADP
admet-843	139	11	the	the	DET
admet-843	139	12	monomers	monomer	NOUN
admet-843	139	13	in	in	ADP
admet-843	139	14	the	the	DET
admet-843	139	15	oligomer	oligomer	NOUN
admet-843	139	16	.	.	PUNCT
admet-843	140	1	tool/	tool/	NUM
admet-843	140	2	cytochrom/	cytochrom/	NUM
admet-843	140	3	oligomer	oligomer	ADJ
admet-843	140	4	ola	ola	PROPN
admet-843	140	5	1u	1u	PROPN
admet-843	140	6	ola	ola	PROPN
admet-843	140	7	2u	2u	PROPN
admet-843	140	8	ola	ola	PROPN
admet-843	140	9	3u	3u	PROPN
admet-843	140	10	ola	ola	PROPN
admet-843	140	11	40u	40u	PROPN
admet-843	140	12	admetsar	admetsar	VERB
admet-843	140	13	cyp3a4s	cyp3a4s	PROPN
admet-843	140	14	-0.84	-0.84	NOUN
admet-843	140	15	-0.71	-0.71	PROPN
admet-843	140	16	-0.69	-0.69	NOUN
admet-843	140	17	cyp2c9s	cyp2c9s	PROPN
admet-843	140	18	0.60	0.60	NUM
admet-843	140	19	0.60	0.60	NUM
admet-843	140	20	0.60	0.60	NUM
admet-843	140	21	cypsd6s	cypsd6s	PROPN
admet-843	140	22	-0.87	-0.87	NUM
admet-843	140	23	-0.88	-0.88	NUM
admet-843	140	24	-0.88	-0.88	PROPN
admet-843	140	25	cyp3a4i	cyp3a4i	PROPN
admet-843	140	26	-0.98	-0.98	NUM
admet-843	140	27	-0.97	-0.97	NOUN
admet-843	140	28	-0.95	-0.95	NUM
admet-843	140	29	cyp2c9i	cyp2c9i	PROPN
admet-843	140	30	-0.88	-0.88	NUM
admet-843	140	31	-0.91	-0.91	NOUN
admet-843	140	32	-0.93	-0.93	INTJ
admet-843	140	33	cyp2c19i	cyp2c19i	ADP
admet-843	140	34	-0.98	-0.98	PUNCT
admet-843	140	35	-0.96	-0.96	NUM
admet-843	140	36	-0.97	-0.97	NOUN
admet-843	140	37	cyp2d6i	cyp2d6i	NOUN
admet-843	140	38	-0.98	-0.98	NUM
admet-843	140	39	-0.96	-0.96	NUM
admet-843	140	40	-0.95	-0.95	NUM
admet-843	140	41	cyp1a2i	cyp1a2i	PROPN
admet-843	140	42	-0.97	-0.97	NOUN
admet-843	140	43	-0.98	-0.98	PRON
admet-843	140	44	-0.98	-0.98	NUM
admet-843	140	45	swiss	swiss	ADJ
admet-843	140	46	adme	adme	NOUN
admet-843	140	47	cyp3a4i	cyp3a4i	VERB
admet-843	141	1	no	no	INTJ
admet-843	141	2	no	no	INTJ
admet-843	141	3	no	no	INTJ
admet-843	141	4	cyp2c9i	cyp2c9i	PROPN
admet-843	142	1	no	no	INTJ
admet-843	142	2	no	no	INTJ
admet-843	142	3	no	no	INTJ
admet-843	142	4	cyp2c19i	cyp2c19i	INTJ
admet-843	142	5	no	no	INTJ
admet-843	142	6	no	no	INTJ
admet-843	142	7	no	no	INTJ
admet-843	142	8	cyp2d6i	cyp2d6i	NOUN
admet-843	142	9	no	no	INTJ
admet-843	142	10	no	no	INTJ
admet-843	143	1	no	no	INTJ
admet-843	143	2	cyp1a2i	cyp1a2i	NOUN
admet-843	144	1	no	no	INTJ
admet-843	144	2	no	no	INTJ
admet-843	145	1	no	no	DET
admet-843	145	2	data	datum	NOUN
admet-843	145	3	presented	present	VERB
admet-843	145	4	in	in	ADP
admet-843	145	5	table	table	NOUN
admet-843	145	6	4	4	NUM
admet-843	145	7	illustrate	illustrate	VERB
admet-843	145	8	that	that	SCONJ
admet-843	145	9	olas	ola	NOUN
admet-843	145	10	are	be	AUX
admet-843	145	11	not	not	PART
admet-843	145	12	considered	consider	VERB
admet-843	145	13	substrates	substrate	NOUN
admet-843	145	14	and	and	CCONJ
admet-843	145	15	inhibitors	inhibitor	NOUN
admet-843	145	16	of	of	ADP
admet-843	145	17	the	the	DET
admet-843	145	18	human	human	ADJ
admet-843	145	19	cytochromes	cytochrome	NOUN
admet-843	145	20	involved	involve	VERB
admet-843	145	21	in	in	ADP
admet-843	145	22	the	the	DET
admet-843	145	23	metabolism	metabolism	NOUN
admet-843	145	24	of	of	ADP
admet-843	145	25	xenobiotics	xenobiotics	PROPN
admet-843	145	26	and	and	CCONJ
admet-843	145	27	their	their	PRON
admet-843	145	28	presence	presence	NOUN
admet-843	145	29	in	in	ADP
admet-843	145	30	the	the	DET
admet-843	145	31	human	human	ADJ
admet-843	145	32	organism	organism	NOUN
admet-843	145	33	do	do	AUX
admet-843	145	34	not	not	PART
admet-843	145	35	interfere	interfere	VERB
admet-843	145	36	with	with	ADP
admet-843	145	37	other	other	ADJ
admet-843	145	38	compounds	compound	NOUN
admet-843	145	39	that	that	PRON
admet-843	145	40	are	be	AUX
admet-843	145	41	metabolized	metabolize	VERB
admet-843	145	42	by	by	ADP
admet-843	145	43	these	these	DET
admet-843	145	44	enzymes	enzyme	NOUN
admet-843	145	45	.	.	PUNCT
admet-843	146	1	we	we	PRON
admet-843	146	2	were	be	AUX
admet-843	146	3	not	not	PART
admet-843	146	4	able	able	ADJ
admet-843	146	5	to	to	PART
admet-843	146	6	find	find	VERB
admet-843	146	7	scientific	scientific	ADJ
admet-843	146	8	literature	literature	NOUN
admet-843	146	9	mentioning	mention	VERB
admet-843	146	10	the	the	DET
admet-843	146	11	effects	effect	NOUN
admet-843	146	12	of	of	ADP
admet-843	146	13	olas	ola	NOUN
admet-843	146	14	or	or	CCONJ
admet-843	146	15	pla	pla	NOUN
admet-843	146	16	on	on	ADP
admet-843	146	17	the	the	DET
admet-843	146	18	human	human	ADJ
admet-843	146	19	cytochromes	cytochrome	NOUN
admet-843	146	20	.	.	PUNCT
admet-843	147	1	the	the	DET
admet-843	147	2	probabilities	probability	NOUN
admet-843	147	3	corresponding	correspond	VERB
admet-843	147	4	to	to	ADP
admet-843	147	5	the	the	DET
admet-843	147	6	ability	ability	NOUN
admet-843	147	7	of	of	ADP
admet-843	147	8	investigated	investigate	VERB
admet-843	147	9	olas	olas	PROPN
admet-843	147	10	to	to	PART
admet-843	147	11	inhibit	inhibit	VERB
admet-843	147	12	the	the	DET
admet-843	147	13	organic	organic	ADJ
admet-843	147	14	anions	anion	NOUN
admet-843	147	15	and/or	and/or	CCONJ
admet-843	147	16	cations	cation	NOUN
admet-843	147	17	transporters	transporter	NOUN
admet-843	147	18	are	be	AUX
admet-843	147	19	presented	present	VERB
admet-843	147	20	in	in	ADP
admet-843	147	21	figure	figure	NOUN
admet-843	147	22	4	4	NUM
admet-843	147	23	.	.	PUNCT
admet-843	147	24	figure	figure	VERB
admet-843	147	25	4	4	NUM
admet-843	147	26	illustrates	illustrate	VERB
admet-843	147	27	that	that	SCONJ
admet-843	147	28	olas	ola	NOUN
admet-843	147	29	are	be	AUX
admet-843	147	30	able	able	ADJ
admet-843	147	31	to	to	PART
admet-843	147	32	inhibit	inhibit	VERB
admet-843	147	33	the	the	DET
admet-843	147	34	liverspecific	liverspecific	NOUN
admet-843	147	35	organic	organic	ADJ
admet-843	147	36	anion	anion	NOUN
admet-843	147	37	transporters	transporter	NOUN
admet-843	147	38	oatp1b1	oatp1b1	X
admet-843	147	39	and	and	CCONJ
admet-843	147	40	oatp1b3	oatp1b3	NOUN
admet-843	147	41	.	.	PUNCT
admet-843	148	1	this	this	DET
admet-843	148	2	possibility	possibility	NOUN
admet-843	148	3	should	should	AUX
admet-843	148	4	be	be	AUX
admet-843	148	5	addressed	address	VERB
admet-843	148	6	in	in	ADP
admet-843	148	7	experimental	experimental	ADJ
admet-843	148	8	studies	study	NOUN
admet-843	148	9	as	as	SCONJ
admet-843	148	10	these	these	DET
admet-843	148	11	transporters	transporter	NOUN
admet-843	148	12	are	be	AUX
admet-843	148	13	of	of	ADP
admet-843	148	14	particular	particular	ADJ
admet-843	148	15	importance	importance	NOUN
admet-843	148	16	for	for	ADP
admet-843	148	17	hepatic	hepatic	ADJ
admet-843	148	18	pharmacokinetics	pharmacokinetic	NOUN
admet-843	148	19	and	and	CCONJ
admet-843	148	20	elimination	elimination	NOUN
admet-843	148	21	of	of	ADP
admet-843	148	22	xenobiotics	xenobiotic	NOUN
admet-843	148	23	,	,	PUNCT
admet-843	148	24	and	and	CCONJ
admet-843	148	25	the	the	DET
admet-843	148	26	inhibition	inhibition	NOUN
admet-843	148	27	of	of	ADP
admet-843	148	28	these	these	DET
admet-843	148	29	transporters	transporter	NOUN
admet-843	148	30	may	may	AUX
admet-843	148	31	result	result	VERB
admet-843	148	32	in	in	ADP
admet-843	148	33	drug	drug	NOUN
admet-843	148	34	–	–	PUNCT
admet-843	148	35	drug	drug	NOUN
admet-843	148	36	interactions	interaction	NOUN
admet-843	148	37	[	[	X
admet-843	148	38	39	39	NUM
admet-843	148	39	]	]	PUNCT
admet-843	148	40	.	.	PUNCT
admet-843	149	1	the	the	DET
admet-843	149	2	potential	potential	NOUN
admet-843	149	3	of	of	ADP
admet-843	149	4	endocrine	endocrine	ADJ
admet-843	149	5	disruption	disruption	NOUN
admet-843	149	6	of	of	ADP
admet-843	149	7	small	small	ADJ
admet-843	149	8	oligomers	oligomer	NOUN
admet-843	149	9	of	of	ADP
admet-843	149	10	olas	olas	PROPN
admet-843	149	11	has	have	AUX
admet-843	149	12	been	be	AUX
admet-843	149	13	obtained	obtain	VERB
admet-843	149	14	using	use	VERB
admet-843	149	15	endocrine	endocrine	NOUN
admet-843	149	16	disruptome	disruptome	NOUN
admet-843	149	17	computational	computational	ADJ
admet-843	149	18	tool	tool	NOUN
admet-843	149	19	and	and	CCONJ
admet-843	149	20	is	be	AUX
admet-843	149	21	presented	present	VERB
admet-843	149	22	in	in	ADP
admet-843	149	23	figure	figure	NOUN
admet-843	149	24	5	5	NUM
admet-843	149	25	.	.	PUNCT
admet-843	150	1	oligomers	oligomer	NOUN
admet-843	150	2	containing	contain	VERB
admet-843	150	3	more	more	ADJ
admet-843	150	4	than	than	ADP
admet-843	150	5	10	10	NUM
admet-843	150	6	lactic	lactic	ADJ
admet-843	150	7	acid	acid	NOUN
admet-843	150	8	units	unit	NOUN
admet-843	150	9	were	be	AUX
admet-843	150	10	too	too	ADV
admet-843	150	11	big	big	ADJ
admet-843	150	12	to	to	PART
admet-843	150	13	accommodate	accommodate	VERB
admet-843	150	14	in	in	ADP
admet-843	150	15	the	the	DET
admet-843	150	16	active	active	ADJ
admet-843	150	17	sites	site	NOUN
admet-843	150	18	of	of	ADP
admet-843	150	19	the	the	DET
admet-843	150	20	considered	consider	VERB
admet-843	150	21	nuclear	nuclear	ADJ
admet-843	150	22	receptors	receptor	NOUN
admet-843	150	23	and	and	CCONJ
admet-843	150	24	the	the	DET
admet-843	150	25	computations	computation	NOUN
admet-843	150	26	have	have	AUX
admet-843	150	27	been	be	AUX
admet-843	150	28	aborted	abort	VERB
admet-843	150	29	.	.	PUNCT
admet-843	151	1	investigated	investigate	VERB
admet-843	151	2	oligomers	oligomer	NOUN
admet-843	151	3	containing	contain	VERB
admet-843	151	4	up	up	ADP
admet-843	151	5	to	to	PART
admet-843	151	6	7	7	NUM
admet-843	151	7	lactic	lactic	ADJ
admet-843	151	8	acid	acid	NOUN
admet-843	151	9	units	unit	NOUN
admet-843	151	10	present	present	VERB
admet-843	151	11	a	a	DET
admet-843	151	12	small	small	ADJ
admet-843	151	13	binding	bind	VERB
admet-843	151	14	capacity	capacity	NOUN
admet-843	151	15	to	to	ADP
admet-843	151	16	the	the	DET
admet-843	151	17	androgen	androgen	NOUN
admet-843	151	18	receptor	receptor	NOUN
admet-843	151	19	in	in	ADP
admet-843	151	20	the	the	DET
admet-843	151	21	antagonistic	antagonistic	ADJ
admet-843	151	22	conformation	conformation	NOUN
admet-843	151	23	,	,	PUNCT
admet-843	151	24	and	and	CCONJ
admet-843	151	25	they	they	PRON
admet-843	151	26	may	may	AUX
admet-843	151	27	produce	produce	VERB
admet-843	151	28	reproductive	reproductive	ADJ
admet-843	151	29	dysfunctions	dysfunction	NOUN
admet-843	151	30	.	.	PUNCT
admet-843	152	1	oligomers	oligomer	NOUN
admet-843	152	2	containing	contain	VERB
admet-843	152	3	from	from	ADP
admet-843	152	4	6	6	NUM
admet-843	152	5	to	to	PART
admet-843	152	6	10	10	NUM
admet-843	152	7	lactic	lactic	ADJ
admet-843	152	8	acid	acid	NOUN
admet-843	152	9	units	unit	NOUN
admet-843	152	10	may	may	AUX
admet-843	152	11	affect	affect	VERB
admet-843	152	12	the	the	DET
admet-843	152	13	glucocorticoid	glucocorticoid	ADJ
admet-843	152	14	receptor	receptor	NOUN
admet-843	152	15	.	.	PUNCT
admet-843	153	1	these	these	DET
admet-843	153	2	results	result	NOUN
admet-843	153	3	are	be	AUX
admet-843	153	4	in	in	ADP
admet-843	153	5	good	good	ADJ
admet-843	153	6	agreement	agreement	NOUN
admet-843	153	7	with	with	ADP
admet-843	153	8	published	publish	VERB
admet-843	153	9	data	datum	NOUN
admet-843	153	10	,	,	PUNCT
admet-843	153	11	zimmerman	zimmerman	PROPN
admet-843	153	12	et	et	PROPN
admet-843	153	13	al	al	PROPN
admet-843	153	14	(	(	PUNCT
admet-843	153	15	2019	2019	NUM
admet-843	153	16	)	)	PUNCT
admet-843	154	1	[	[	X
admet-843	154	2	13	13	NUM
admet-843	154	3	]	]	PUNCT
admet-843	154	4	illustrated	illustrate	VERB
admet-843	154	5	that	that	SCONJ
admet-843	154	6	pla	pla	PROPN
admet-843	154	7	may	may	AUX
admet-843	154	8	have	have	VERB
admet-843	154	9	estrogenic	estrogenic	ADJ
admet-843	154	10	effects	effect	NOUN
admet-843	154	11	.	.	PUNCT
admet-843	155	1	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	PROPN
admet-843	155	2	d.	d.	PROPN
admet-843	155	3	dascălu	dascălu	PROPN
admet-843	155	4	et	et	PROPN
admet-843	155	5	al	al	PROPN
admet-843	155	6	.	.	PROPN
admet-843	155	7	admet	admet	PROPN
admet-843	155	8	&	&	CCONJ
admet-843	155	9	dmpk	dmpk	PROPN
admet-843	155	10	8(4	8(4	NOUN
admet-843	155	11	)	)	PUNCT
admet-843	155	12	(	(	PUNCT
admet-843	155	13	2020	2020	NUM
admet-843	155	14	)	)	PUNCT
admet-843	155	15	425	425	NUM
admet-843	155	16	-	-	SYM
admet-843	155	17	436	436	NUM
admet-843	155	18	432	432	NUM
admet-843	155	19	figure	figure	NOUN
admet-843	155	20	4	4	NUM
admet-843	155	21	.	.	PUNCT
admet-843	155	22	probabilities	probability	NOUN
admet-843	155	23	of	of	ADP
admet-843	155	24	investigated	investigate	VERB
admet-843	155	25	olas	olas	PROPN
admet-843	155	26	to	to	PART
admet-843	155	27	inhibit	inhibit	VERB
admet-843	155	28	(	(	PUNCT
admet-843	155	29	positive	positive	ADJ
admet-843	155	30	values	value	NOUN
admet-843	155	31	)	)	PUNCT
admet-843	155	32	or	or	CCONJ
admet-843	155	33	not	not	PART
admet-843	155	34	inhibit	inhibit	VERB
admet-843	155	35	(	(	PUNCT
admet-843	155	36	negative	negative	ADJ
admet-843	155	37	values	value	NOUN
admet-843	155	38	)	)	PUNCT
admet-843	155	39	the	the	DET
admet-843	155	40	organic	organic	ADJ
admet-843	155	41	anions	anion	NOUN
admet-843	155	42	and/or	and/or	CCONJ
admet-843	155	43	cations	cation	NOUN
admet-843	155	44	transporters	transporter	NOUN
admet-843	155	45	(	(	PUNCT
admet-843	155	46	oatp	oatp	ADJ
admet-843	155	47	/	/	SYM
admet-843	155	48	oct	oct	NOUN
admet-843	155	49	)	)	PUNCT
admet-843	155	50	obtained	obtain	VERB
admet-843	155	51	using	use	VERB
admet-843	155	52	admetsar	admetsar	ADJ
admet-843	155	53	tool	tool	NOUN
admet-843	155	54	.	.	PUNCT
admet-843	156	1	the	the	DET
admet-843	156	2	notation	notation	NOUN
admet-843	156	3	”	"	PUNCT
admet-843	156	4	u	u	NOUN
admet-843	156	5	”	"	PUNCT
admet-843	156	6	refers	refer	VERB
admet-843	156	7	to	to	ADP
admet-843	156	8	the	the	DET
admet-843	156	9	number	number	NOUN
admet-843	156	10	of	of	ADP
admet-843	156	11	the	the	DET
admet-843	156	12	monomers	monomer	NOUN
admet-843	156	13	in	in	ADP
admet-843	156	14	the	the	DET
admet-843	156	15	oligomer	oligomer	NOUN
admet-843	156	16	.	.	PUNCT
admet-843	157	1	figure	figure	NOUN
admet-843	157	2	5	5	NUM
admet-843	157	3	.	.	PUNCT
admet-843	158	1	predictions	prediction	NOUN
admet-843	158	2	obtained	obtain	VERB
admet-843	158	3	using	use	VERB
admet-843	158	4	endocrine	endocrine	NOUN
admet-843	158	5	disruptome	disruptome	NOUN
admet-843	158	6	computational	computational	ADJ
admet-843	158	7	tool	tool	NOUN
admet-843	158	8	to	to	PART
admet-843	158	9	assess	assess	VERB
admet-843	158	10	the	the	DET
admet-843	158	11	endocrine	endocrine	ADJ
admet-843	158	12	disruption	disruption	NOUN
admet-843	158	13	potential	potential	NOUN
admet-843	158	14	of	of	ADP
admet-843	158	15	investigated	investigate	VERB
admet-843	158	16	olas	ola	NOUN
admet-843	158	17	:	:	PUNCT
admet-843	158	18	ar	ar	NOUN
admet-843	158	19	androgen	androgen	NOUN
admet-843	158	20	receptor	receptor	NOUN
admet-843	158	21	,	,	PUNCT
admet-843	158	22	erα	erα	NOUN
admet-843	158	23	and	and	CCONJ
admet-843	158	24	erβ	erβ	ADJ
admet-843	158	25	oestrogen	oestrogen	NOUN
admet-843	158	26	receptors	receptor	NOUN
admet-843	158	27	α	α	NOUN
admet-843	158	28	and	and	CCONJ
admet-843	158	29	β	β	X
admet-843	158	30	,	,	PUNCT
admet-843	158	31	gr	gr	ADP
admet-843	158	32	glucocorticoid	glucocorticoid	ADJ
admet-843	158	33	receptor	receptor	NOUN
admet-843	158	34	,	,	PUNCT
admet-843	158	35	lxrα	lxrα	VERB
admet-843	158	36	and	and	CCONJ
admet-843	158	37	lrxβ	lrxβ	VERB
admet-843	159	1	liver	liver	NOUN
admet-843	159	2	x	x	NOUN
admet-843	159	3	receptors	receptor	NOUN
admet-843	159	4	α	α	NOUN
admet-843	159	5	and	and	CCONJ
admet-843	159	6	β	β	NOUN
admet-843	159	7	,	,	PUNCT
admet-843	159	8	ppraα	ppraα	ADJ
admet-843	159	9	,	,	PUNCT
admet-843	159	10	ppraβ	ppraβ	PRON
admet-843	159	11	and	and	CCONJ
admet-843	159	12	ppraγ	ppraγ	PROPN
admet-843	159	13	peroxisome	peroxisome	PROPN
admet-843	159	14	proliferator	proliferator	NOUN
admet-843	159	15	activated	activate	VERB
admet-843	159	16	receptors	receptor	NOUN
admet-843	159	17	α	α	NOUN
admet-843	159	18	,	,	PUNCT
admet-843	159	19	β	β	X
admet-843	159	20	/	/	SYM
admet-843	159	21	δ	δ	PROPN
admet-843	159	22	and	and	CCONJ
admet-843	159	23	γ	γ	PROPN
admet-843	159	24	,	,	PUNCT
admet-843	159	25	rxrα	rxrα	VERB
admet-843	159	26	retinoid	retinoid	NOUN
admet-843	159	27	x	x	SYM
admet-843	159	28	receptor	receptor	NOUN
admet-843	159	29	α	α	NOUN
admet-843	159	30	,	,	PUNCT
admet-843	159	31	trα	trα	NOUN
admet-843	160	1	and	and	CCONJ
admet-843	160	2	trβ	trβ	PROPN
admet-843	160	3	thyroid	thyroid	NOUN
admet-843	160	4	receptors	receptor	NOUN
admet-843	160	5	α	α	NOUN
admet-843	160	6	and	and	CCONJ
admet-843	160	7	β	β	X
admet-843	160	8	.	.	PUNCT
admet-843	161	1	both	both	CCONJ
admet-843	161	2	agonistic	agonistic	ADJ
admet-843	161	3	and	and	CCONJ
admet-843	161	4	antagonistic	antagonistic	ADJ
admet-843	161	5	(	(	PUNCT
admet-843	161	6	an	an	NOUN
admet-843	161	7	)	)	PUNCT
admet-843	161	8	effects	effect	NOUN
admet-843	161	9	for	for	ADP
admet-843	161	10	the	the	DET
admet-843	161	11	nuclear	nuclear	ADJ
admet-843	161	12	receptors	receptor	NOUN
admet-843	161	13	ar	ar	PROPN
admet-843	161	14	,	,	PUNCT
admet-843	161	15	erα	erα	ADJ
admet-843	161	16	,	,	PUNCT
admet-843	161	17	erβ	erβ	PROPN
admet-843	161	18	and	and	CCONJ
admet-843	161	19	gr	gr	NOUN
admet-843	161	20	are	be	AUX
admet-843	161	21	predicted	predict	VERB
admet-843	161	22	.	.	PUNCT
admet-843	162	1	the	the	DET
admet-843	162	2	notation	notation	NOUN
admet-843	162	3	”	"	PUNCT
admet-843	162	4	u	u	NOUN
admet-843	162	5	”	"	PUNCT
admet-843	162	6	refers	refer	VERB
admet-843	162	7	to	to	ADP
admet-843	162	8	the	the	DET
admet-843	162	9	number	number	NOUN
admet-843	162	10	of	of	ADP
admet-843	162	11	the	the	DET
admet-843	162	12	monomers	monomer	NOUN
admet-843	162	13	in	in	ADP
admet-843	162	14	the	the	DET
admet-843	162	15	oligomer	oligomer	NOUN
admet-843	162	16	.	.	PUNCT
admet-843	163	1	oligomers	oligomer	NOUN
admet-843	163	2	containing	contain	VERB
admet-843	163	3	more	more	ADJ
admet-843	163	4	than	than	ADP
admet-843	163	5	10	10	NUM
admet-843	163	6	lactic	lactic	ADJ
admet-843	163	7	acid	acid	NOUN
admet-843	163	8	units	unit	NOUN
admet-843	163	9	were	be	AUX
admet-843	163	10	too	too	ADV
admet-843	163	11	big	big	ADJ
admet-843	163	12	to	to	PART
admet-843	163	13	accommodate	accommodate	VERB
admet-843	163	14	in	in	ADP
admet-843	163	15	the	the	DET
admet-843	163	16	active	active	ADJ
admet-843	163	17	sites	site	NOUN
admet-843	163	18	of	of	ADP
admet-843	163	19	the	the	DET
admet-843	163	20	considered	consider	VERB
admet-843	163	21	nuclear	nuclear	ADJ
admet-843	163	22	receptors	receptor	NOUN
admet-843	163	23	and	and	CCONJ
admet-843	163	24	the	the	DET
admet-843	163	25	computations	computation	NOUN
admet-843	163	26	have	have	AUX
admet-843	163	27	been	be	AUX
admet-843	163	28	aborted	abort	VERB
admet-843	163	29	.	.	PUNCT
admet-843	164	1	the	the	DET
admet-843	164	2	results	result	NOUN
admet-843	164	3	that	that	PRON
admet-843	164	4	we	we	PRON
admet-843	164	5	have	have	AUX
admet-843	164	6	obtained	obtain	VERB
admet-843	164	7	for	for	ADP
admet-843	164	8	the	the	DET
admet-843	164	9	organ	organ	NOUN
admet-843	164	10	and	and	CCONJ
admet-843	164	11	genomic	genomic	NOUN
admet-843	164	12	toxicity	toxicity	NOUN
admet-843	164	13	of	of	ADP
admet-843	164	14	small	small	ADJ
admet-843	164	15	olas	ola	NOUN
admet-843	164	16	using	use	VERB
admet-843	164	17	all	all	DET
admet-843	164	18	considered	consider	VERB
admet-843	164	19	computational	computational	ADJ
admet-843	164	20	tools	tool	NOUN
admet-843	164	21	mentioned	mention	VERB
admet-843	164	22	above	above	ADV
admet-843	164	23	are	be	AUX
admet-843	164	24	presented	present	VERB
admet-843	164	25	in	in	ADP
admet-843	164	26	figure	figure	NOUN
admet-843	164	27	6	6	NUM
admet-843	164	28	.	.	PUNCT
admet-843	165	1	none	none	NOUN
admet-843	165	2	of	of	ADP
admet-843	165	3	the	the	DET
admet-843	165	4	investigated	investigate	VERB
admet-843	165	5	compounds	compound	NOUN
admet-843	165	6	reflects	reflect	VERB
admet-843	165	7	skin	skin	NOUN
admet-843	165	8	sensitization	sensitization	NOUN
admet-843	165	9	potential	potential	NOUN
admet-843	165	10	,	,	PUNCT
admet-843	165	11	cardiotoxicity	cardiotoxicity	NOUN
admet-843	165	12	,	,	PUNCT
admet-843	165	13	carcinogenicity	carcinogenicity	NOUN
admet-843	165	14	and	and	CCONJ
admet-843	165	15	mutagenicity	mutagenicity	NOUN
admet-843	165	16	.	.	PUNCT
admet-843	166	1	all	all	DET
admet-843	166	2	investigated	investigate	VERB
admet-843	166	3	oligomers	oligomer	NOUN
admet-843	166	4	are	be	AUX
admet-843	166	5	considered	consider	VERB
admet-843	166	6	to	to	PART
admet-843	166	7	be	be	AUX
admet-843	166	8	able	able	ADJ
admet-843	166	9	to	to	PART
admet-843	166	10	produce	produce	VERB
admet-843	166	11	eye	eye	NOUN
admet-843	166	12	corrosion	corrosion	NOUN
admet-843	166	13	and	and	CCONJ
admet-843	166	14	smaller	small	ADJ
admet-843	166	15	oligomers	oligomer	NOUN
admet-843	166	16	(	(	PUNCT
admet-843	166	17	from	from	ADP
admet-843	166	18	1	1	NUM
admet-843	166	19	to	to	PART
admet-843	166	20	3	3	NUM
admet-843	166	21	lactic	lactic	ADJ
admet-843	166	22	acid	acid	NOUN
admet-843	166	23	units	unit	NOUN
admet-843	166	24	)	)	PUNCT
admet-843	166	25	may	may	AUX
admet-843	166	26	also	also	ADV
admet-843	166	27	produce	produce	VERB
admet-843	166	28	eye	eye	NOUN
admet-843	166	29	irritations	irritation	NOUN
admet-843	166	30	and	and	CCONJ
admet-843	166	31	olas	ola	NOUN
admet-843	166	32	containing	contain	VERB
admet-843	166	33	at	at	ADV
admet-843	166	34	least	least	ADV
admet-843	166	35	5	5	NUM
admet-843	166	36	units	unit	NOUN
admet-843	166	37	of	of	ADP
admet-843	166	38	lactic	lactic	ADJ
admet-843	166	39	acids	acid	NOUN
admet-843	166	40	emphasize	emphasize	VERB
admet-843	166	41	a	a	DET
admet-843	166	42	weak	weak	ADJ
admet-843	166	43	potential	potential	NOUN
admet-843	166	44	of	of	ADP
admet-843	166	45	hepatotoxicity	hepatotoxicity	NOUN
admet-843	166	46	.	.	PUNCT
admet-843	167	1	literature	literature	NOUN
admet-843	167	2	data	datum	NOUN
admet-843	167	3	reveal	reveal	VERB
admet-843	167	4	one	one	NUM
admet-843	167	5	case	case	NOUN
admet-843	167	6	of	of	ADP
admet-843	167	7	blindness	blindness	NOUN
admet-843	167	8	and	and	CCONJ
admet-843	167	9	ophthalmoplegia	ophthalmoplegia	NOUN
admet-843	167	10	following	follow	VERB
admet-843	167	11	a	a	DET
admet-843	167	12	treatment	treatment	NOUN
admet-843	167	13	of	of	ADP
admet-843	167	14	the	the	DET
admet-843	167	15	left	left	ADJ
admet-843	167	16	periorbital	periorbital	ADJ
admet-843	167	17	region	region	NOUN
admet-843	167	18	with	with	ADP
admet-843	167	19	the	the	DET
admet-843	167	20	subcutaneous	subcutaneous	ADJ
admet-843	167	21	filler	filler	NOUN
admet-843	167	22	of	of	ADP
admet-843	167	23	pla	pla	NOUN
admet-843	168	1	[	[	X
admet-843	168	2	40	40	NUM
admet-843	168	3	]	]	PUNCT
admet-843	168	4	.	.	PUNCT
admet-843	169	1	in	in	ADP
admet-843	169	2	vitro	vitro	X
admet-843	169	3	and	and	CCONJ
admet-843	169	4	in	in	ADP
admet-843	169	5	vivo	vivo	NOUN
admet-843	169	6	animal	animal	NOUN
admet-843	169	7	data	datum	NOUN
admet-843	169	8	illustrated	illustrate	VERB
admet-843	169	9	that	that	SCONJ
admet-843	169	10	lactic	lactic	ADJ
admet-843	169	11	acid	acid	NOUN
admet-843	169	12	has	have	VERB
admet-843	169	13	skin	skin	NOUN
admet-843	169	14	and	and	CCONJ
admet-843	169	15	eye	eye	NOUN
admet-843	169	16	irritation	irritation	NOUN
admet-843	169	17	potential	potential	NOUN
admet-843	169	18	(	(	PUNCT
admet-843	169	19	pubchem	pubchem	NOUN
admet-843	169	20	,	,	PUNCT
admet-843	169	21	accessed	access	VERB
admet-843	169	22	in	in	ADP
admet-843	169	23	24	24	NUM
admet-843	169	24	of	of	ADP
admet-843	169	25	april	april	PROPN
admet-843	169	26	,	,	PUNCT
admet-843	169	27	2020	2020	NUM
admet-843	169	28	)	)	PUNCT
admet-843	169	29	.	.	PUNCT
admet-843	170	1	admet	admet	PROPN
admet-843	170	2	&	&	CCONJ
admet-843	170	3	dmpk	dmpk	PROPN
admet-843	170	4	8(4	8(4	NOUN
admet-843	170	5	)	)	PUNCT
admet-843	170	6	(	(	PUNCT
admet-843	170	7	2020	2020	NUM
admet-843	170	8	)	)	PUNCT
admet-843	170	9	425	425	NUM
admet-843	170	10	-	-	SYM
admet-843	170	11	436	436	NUM
admet-843	170	12	admet	admet	NOUN
admet-843	170	13	profiles	profile	NOUN
admet-843	170	14	of	of	ADP
admet-843	170	15	oligomers	oligomer	NOUN
admet-843	170	16	of	of	ADP
admet-843	170	17	lactic	lactic	ADJ
admet-843	170	18	acid	acid	NOUN
admet-843	170	19	doi	doi	NOUN
admet-843	170	20	:	:	PUNCT
admet-843	170	21	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	NOUN
admet-843	170	22	433	433	NUM
admet-843	170	23	figure	figure	NOUN
admet-843	170	24	6	6	NUM
admet-843	170	25	.	.	PUNCT
admet-843	170	26	predictions	prediction	NOUN
admet-843	170	27	of	of	ADP
admet-843	170	28	organ	organ	NOUN
admet-843	170	29	and	and	CCONJ
admet-843	170	30	genomic	genomic	NOUN
admet-843	170	31	toxicity	toxicity	NOUN
admet-843	170	32	of	of	ADP
admet-843	170	33	small	small	ADJ
admet-843	170	34	olas	ola	NOUN
admet-843	170	35	:	:	PUNCT
admet-843	170	36	green	green	ADJ
admet-843	170	37	cells	cell	NOUN
admet-843	170	38	illustrate	illustrate	VERB
admet-843	170	39	non	non	ADJ
admet-843	170	40	-	-	NOUN
admet-843	170	41	toxicity	toxicity	ADJ
admet-843	170	42	and	and	CCONJ
admet-843	170	43	yellow	yellow	ADJ
admet-843	170	44	cells	cell	NOUN
admet-843	170	45	illustrate	illustrate	VERB
admet-843	170	46	possible	possible	ADJ
admet-843	170	47	toxicological	toxicological	ADJ
admet-843	170	48	effects	effect	NOUN
admet-843	170	49	.	.	PUNCT
admet-843	171	1	the	the	DET
admet-843	171	2	notation	notation	NOUN
admet-843	171	3	”	"	PUNCT
admet-843	171	4	u	u	NOUN
admet-843	171	5	”	"	PUNCT
admet-843	171	6	refers	refer	VERB
admet-843	171	7	to	to	ADP
admet-843	171	8	the	the	DET
admet-843	171	9	number	number	NOUN
admet-843	171	10	of	of	ADP
admet-843	171	11	the	the	DET
admet-843	171	12	monomers	monomer	NOUN
admet-843	171	13	in	in	ADP
admet-843	171	14	the	the	DET
admet-843	171	15	oligomer	oligomer	NOUN
admet-843	171	16	and	and	CCONJ
admet-843	171	17	crg	crg	PROPN
admet-843	171	18	means	mean	NOUN
admet-843	171	19	carcinogenicty	carcinogenicty	PROPN
admet-843	171	20	.	.	PUNCT
admet-843	172	1	also	also	ADV
admet-843	172	2	,	,	PUNCT
admet-843	172	3	literature	literature	NOUN
admet-843	172	4	data	datum	NOUN
admet-843	172	5	mention	mention	VERB
admet-843	172	6	non	non	ADJ
admet-843	172	7	-	-	NOUN
admet-843	172	8	carcinogenicity	carcinogenicity	NOUN
admet-843	172	9	[	[	X
admet-843	172	10	41	41	NUM
admet-843	172	11	]	]	PUNCT
admet-843	172	12	,	,	PUNCT
admet-843	172	13	non	non	ADJ
admet-843	172	14	-	-	NOUN
admet-843	172	15	mutagenicity	mutagenicity	NOUN
admet-843	172	16	[	[	X
admet-843	172	17	42	42	NUM
admet-843	172	18	]	]	PUNCT
admet-843	172	19	,	,	PUNCT
admet-843	172	20	non	non	ADJ
admet-843	172	21	-	-	ADJ
admet-843	172	22	hepatotoxicity	hepatotoxicity	ADJ
admet-843	172	23	and	and	CCONJ
admet-843	172	24	non	non	ADJ
admet-843	172	25	-	-	ADJ
admet-843	172	26	skin	skin	ADJ
admet-843	172	27	sensitization	sensitization	NOUN
admet-843	172	28	potential	potential	NOUN
admet-843	173	1	[	[	X
admet-843	173	2	43	43	NUM
admet-843	173	3	]	]	PUNCT
admet-843	173	4	of	of	ADP
admet-843	173	5	pla	pla	NOUN
admet-843	173	6	.	.	PUNCT
admet-843	174	1	we	we	PRON
admet-843	174	2	were	be	AUX
admet-843	174	3	not	not	PART
admet-843	174	4	able	able	ADJ
admet-843	174	5	to	to	PART
admet-843	174	6	find	find	VERB
admet-843	174	7	information	information	NOUN
admet-843	174	8	concerning	concern	VERB
admet-843	174	9	the	the	DET
admet-843	174	10	cardiotoxicity	cardiotoxicity	NOUN
admet-843	174	11	of	of	ADP
admet-843	174	12	this	this	DET
admet-843	174	13	polymer	polymer	NOUN
admet-843	174	14	and	and	CCONJ
admet-843	174	15	of	of	ADP
admet-843	174	16	the	the	DET
admet-843	174	17	investigated	investigate	VERB
admet-843	174	18	oligomers	oligomer	NOUN
admet-843	174	19	.	.	PUNCT
admet-843	175	1	conclusions	conclusion	NOUN
admet-843	175	2	within	within	ADP
admet-843	175	3	this	this	DET
admet-843	175	4	study	study	NOUN
admet-843	175	5	,	,	PUNCT
admet-843	175	6	we	we	PRON
admet-843	175	7	have	have	AUX
admet-843	175	8	predicted	predict	VERB
admet-843	175	9	the	the	DET
admet-843	175	10	solubility	solubility	NOUN
admet-843	175	11	and	and	CCONJ
admet-843	175	12	admet	admet	PROPN
admet-843	175	13	profiles	profile	NOUN
admet-843	175	14	of	of	ADP
admet-843	175	15	short	short	ADJ
admet-843	175	16	oligomers	oligomer	NOUN
admet-843	175	17	of	of	ADP
admet-843	175	18	poly	poly	ADJ
admet-843	175	19	-	-	PUNCT
admet-843	175	20	lactic	lactic	ADJ
admet-843	175	21	acid	acid	NOUN
admet-843	175	22	(	(	PUNCT
admet-843	175	23	containing	contain	VERB
admet-843	175	24	from	from	ADP
admet-843	175	25	1	1	NUM
admet-843	175	26	to	to	PART
admet-843	175	27	40	40	NUM
admet-843	175	28	lactic	lactic	ADJ
admet-843	175	29	acid	acid	NOUN
admet-843	175	30	units	unit	NOUN
admet-843	175	31	,	,	PUNCT
admet-843	175	32	olas	olas	PROPN
admet-843	175	33	)	)	PUNCT
admet-843	175	34	that	that	PRON
admet-843	175	35	may	may	AUX
admet-843	175	36	be	be	AUX
admet-843	175	37	released	release	VERB
admet-843	175	38	during	during	ADP
admet-843	175	39	the	the	DET
admet-843	175	40	degradation	degradation	NOUN
admet-843	175	41	in	in	ADP
admet-843	175	42	the	the	DET
admet-843	175	43	human	human	ADJ
admet-843	175	44	organisms	organism	NOUN
admet-843	175	45	.	.	PUNCT
admet-843	176	1	the	the	DET
admet-843	176	2	outcomes	outcome	NOUN
admet-843	176	3	of	of	ADP
admet-843	176	4	our	our	PRON
admet-843	176	5	computational	computational	ADJ
admet-843	176	6	study	study	NOUN
admet-843	176	7	reveal	reveal	VERB
admet-843	176	8	a	a	DET
admet-843	176	9	linear	linear	ADJ
admet-843	176	10	decrease	decrease	NOUN
admet-843	176	11	of	of	ADP
admet-843	176	12	the	the	DET
admet-843	176	13	solubility	solubility	NOUN
admet-843	176	14	of	of	ADP
admet-843	176	15	olas	olas	PROPN
admet-843	176	16	with	with	ADP
admet-843	176	17	molecular	molecular	ADJ
admet-843	176	18	weight	weight	NOUN
admet-843	176	19	and	and	CCONJ
admet-843	176	20	logp	logp	NOUN
admet-843	176	21	respectively	respectively	ADV
admet-843	176	22	.	.	PUNCT
admet-843	177	1	the	the	DET
admet-843	177	2	low	low	ADJ
admet-843	177	3	aqueous	aqueous	ADJ
admet-843	177	4	solubility	solubility	NOUN
admet-843	177	5	of	of	ADP
admet-843	177	6	oals	oal	NOUN
admet-843	177	7	is	be	AUX
admet-843	177	8	an	an	DET
admet-843	177	9	important	important	ADJ
admet-843	177	10	factor	factor	NOUN
admet-843	177	11	limiting	limit	VERB
admet-843	177	12	the	the	DET
admet-843	177	13	hydrolysis	hydrolysis	NOUN
admet-843	177	14	processes	process	NOUN
admet-843	177	15	and	and	CCONJ
admet-843	177	16	the	the	DET
admet-843	177	17	linear	linear	ADJ
admet-843	177	18	decreases	decrease	NOUN
admet-843	177	19	of	of	ADP
admet-843	177	20	logs	log	NOUN
admet-843	177	21	with	with	ADP
admet-843	177	22	the	the	DET
admet-843	177	23	molecular	molecular	ADJ
admet-843	177	24	weight	weight	NOUN
admet-843	177	25	may	may	AUX
admet-843	177	26	be	be	AUX
admet-843	177	27	used	use	VERB
admet-843	177	28	as	as	ADP
admet-843	177	29	an	an	DET
admet-843	177	30	evaluating	evaluating	NOUN
admet-843	177	31	tool	tool	NOUN
admet-843	177	32	for	for	ADP
admet-843	177	33	predicting	predict	VERB
admet-843	177	34	the	the	DET
admet-843	177	35	olas	olas	PROPN
admet-843	177	36	behaviour	behaviour	NOUN
admet-843	177	37	in	in	ADP
admet-843	177	38	aqueous	aqueous	ADJ
admet-843	177	39	environments	environment	NOUN
admet-843	177	40	.	.	PUNCT
admet-843	178	1	although	although	SCONJ
admet-843	178	2	the	the	DET
admet-843	178	3	oligomers	oligomer	NOUN
admet-843	178	4	of	of	ADP
admet-843	178	5	the	the	DET
admet-843	178	6	biodegradable	biodegradable	ADJ
admet-843	178	7	polymers	polymer	NOUN
admet-843	178	8	are	be	AUX
admet-843	178	9	considered	consider	VERB
admet-843	178	10	to	to	PART
admet-843	178	11	be	be	AUX
admet-843	178	12	easily	easily	ADV
admet-843	178	13	excreted	excrete	VERB
admet-843	178	14	through	through	ADP
admet-843	178	15	common	common	ADJ
admet-843	178	16	metabolic	metabolic	NOUN
admet-843	178	17	pathways	pathway	NOUN
admet-843	178	18	,	,	PUNCT
admet-843	178	19	their	their	PRON
admet-843	178	20	possible	possible	ADJ
admet-843	178	21	toxic	toxic	ADJ
admet-843	178	22	effects	effect	NOUN
admet-843	178	23	need	need	VERB
admet-843	178	24	to	to	PART
admet-843	178	25	be	be	AUX
admet-843	178	26	deeply	deeply	ADV
admet-843	178	27	understood	understand	VERB
admet-843	178	28	and	and	CCONJ
admet-843	178	29	detailed	detailed	ADJ
admet-843	178	30	studies	study	NOUN
admet-843	178	31	must	must	AUX
admet-843	178	32	be	be	AUX
admet-843	178	33	conducted	conduct	VERB
admet-843	178	34	.	.	PUNCT
admet-843	179	1	admet	admet	PROPN
admet-843	179	2	profile	profile	PROPN
admet-843	179	3	assessment	assessment	NOUN
admet-843	179	4	for	for	ADP
admet-843	179	5	investigated	investigate	VERB
admet-843	179	6	olas	olas	PROPN
admet-843	179	7	reveals	reveal	VERB
admet-843	179	8	their	their	PRON
admet-843	179	9	favourable	favourable	ADJ
admet-843	179	10	pharmacological	pharmacological	ADJ
admet-843	179	11	profiles	profile	NOUN
admet-843	179	12	and	and	CCONJ
admet-843	179	13	limited	limited	ADJ
admet-843	179	14	toxicological	toxicological	ADJ
admet-843	179	15	effects	effect	NOUN
admet-843	179	16	on	on	ADP
admet-843	179	17	humans	human	NOUN
admet-843	179	18	.	.	PUNCT
admet-843	180	1	according	accord	VERB
admet-843	180	2	to	to	ADP
admet-843	180	3	the	the	DET
admet-843	180	4	outcomes	outcome	NOUN
admet-843	180	5	of	of	ADP
admet-843	180	6	the	the	DET
admet-843	180	7	computational	computational	ADJ
admet-843	180	8	tools	tool	NOUN
admet-843	180	9	that	that	PRON
admet-843	180	10	we	we	PRON
admet-843	180	11	have	have	AUX
admet-843	180	12	used	use	VERB
admet-843	180	13	,	,	PUNCT
admet-843	180	14	these	these	DET
admet-843	180	15	oligomers	oligomer	NOUN
admet-843	180	16	may	may	AUX
admet-843	180	17	inhibit	inhibit	VERB
admet-843	180	18	the	the	DET
admet-843	180	19	organic	organic	ADJ
admet-843	180	20	anion	anion	NOUN
admet-843	180	21	transporting	transport	VERB
admet-843	180	22	peptides	peptide	NOUN
admet-843	180	23	oatp1b1	oatp1b1	NOUN
admet-843	180	24	and/or	and/or	CCONJ
admet-843	180	25	oatp1b3	oatp1b3	PROPN
admet-843	180	26	,	,	PUNCT
admet-843	180	27	they	they	PRON
admet-843	180	28	illustrate	illustrate	VERB
admet-843	180	29	a	a	DET
admet-843	180	30	minor	minor	ADJ
admet-843	180	31	probability	probability	NOUN
admet-843	180	32	of	of	ADP
admet-843	180	33	affecting	affect	VERB
admet-843	180	34	the	the	DET
admet-843	180	35	androgen	androgen	NOUN
admet-843	180	36	and	and	CCONJ
admet-843	180	37	glucocorticoid	glucocorticoid	ADJ
admet-843	180	38	receptors	receptor	NOUN
admet-843	180	39	,	,	PUNCT
admet-843	180	40	have	have	VERB
admet-843	180	41	a	a	DET
admet-843	180	42	weak	weak	ADJ
admet-843	180	43	potential	potential	NOUN
admet-843	180	44	of	of	ADP
admet-843	180	45	hepatotoxicity	hepatotoxicity	NOUN
admet-843	180	46	,	,	PUNCT
admet-843	180	47	and	and	CCONJ
admet-843	180	48	may	may	AUX
admet-843	180	49	produce	produce	VERB
admet-843	180	50	eye	eye	NOUN
admet-843	180	51	injuries	injury	NOUN
admet-843	180	52	.	.	PUNCT
admet-843	181	1	these	these	DET
admet-843	181	2	outcomes	outcome	NOUN
admet-843	181	3	may	may	AUX
admet-843	181	4	be	be	AUX
admet-843	181	5	used	use	VERB
admet-843	181	6	to	to	PART
admet-843	181	7	define	define	VERB
admet-843	181	8	further	further	ADJ
admet-843	181	9	experimental	experimental	ADJ
admet-843	181	10	measurements	measurement	NOUN
admet-843	181	11	needed	need	VERB
admet-843	181	12	to	to	PART
admet-843	181	13	improve	improve	VERB
admet-843	181	14	our	our	PRON
admet-843	181	15	understanding	understanding	NOUN
admet-843	181	16	of	of	ADP
admet-843	181	17	the	the	DET
admet-843	181	18	effects	effect	NOUN
admet-843	181	19	of	of	ADP
admet-843	181	20	the	the	DET
admet-843	181	21	product	product	NOUN
admet-843	181	22	of	of	ADP
admet-843	181	23	pla	pla	PROPN
admet-843	181	24	degradation	degradation	NOUN
admet-843	181	25	.	.	PUNCT
admet-843	182	1	acknowledgements	acknowledgement	NOUN
admet-843	182	2	:	:	PUNCT
admet-843	182	3	this	this	DET
admet-843	182	4	work	work	NOUN
admet-843	182	5	was	be	AUX
admet-843	182	6	supported	support	VERB
admet-843	182	7	by	by	ADP
admet-843	182	8	the	the	DET
admet-843	182	9	grant	grant	NOUN
admet-843	182	10	pniii	pniii	NOUN
admet-843	182	11	-	-	PUNCT
admet-843	182	12	p3	p3	NOUN
admet-843	182	13	-	-	PUNCT
admet-843	182	14	285	285	NUM
admet-843	182	15	,	,	PUNCT
admet-843	182	16	polymeric	polymeric	ADJ
admet-843	182	17	nanobiomaterials	nanobiomaterial	NOUN
admet-843	182	18	for	for	ADP
admet-843	182	19	drug	drug	NOUN
admet-843	182	20	delivery	delivery	NOUN
admet-843	182	21	:	:	PUNCT
admet-843	182	22	developing	developing	NOUN
admet-843	182	23	and	and	CCONJ
admet-843	182	24	implementation	implementation	NOUN
admet-843	182	25	of	of	ADP
admet-843	182	26	safe	safe	ADJ
admet-843	182	27	-	-	PUNCT
admet-843	182	28	by	by	ADP
admet-843	182	29	-	-	PUNCT
admet-843	182	30	design	design	NOUN
admet-843	182	31	concept	concept	NOUN
admet-843	182	32	enabling	enable	VERB
admet-843	182	33	safe	safe	ADJ
admet-843	182	34	healthcare	healthcare	NOUN
admet-843	182	35	solutions	solution	NOUN
admet-843	182	36	.	.	PUNCT
admet-843	183	1	conflict	conflict	NOUN
admet-843	183	2	of	of	ADP
admet-843	183	3	interest	interest	NOUN
admet-843	183	4	:	:	PUNCT
admet-843	183	5	the	the	DET
admet-843	183	6	authors	author	NOUN
admet-843	183	7	declare	declare	VERB
admet-843	183	8	no	no	DET
admet-843	183	9	conflict	conflict	NOUN
admet-843	183	10	of	of	ADP
admet-843	183	11	interest	interest	NOUN
admet-843	183	12	.	.	PUNCT
admet-843	184	1	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	PROPN
admet-843	184	2	d.	d.	PROPN
admet-843	184	3	dascălu	dascălu	PROPN
admet-843	184	4	et	et	PROPN
admet-843	184	5	al	al	PROPN
admet-843	184	6	.	.	PROPN
admet-843	184	7	admet	admet	PROPN
admet-843	184	8	&	&	CCONJ
admet-843	184	9	dmpk	dmpk	PROPN
admet-843	184	10	8(4	8(4	NOUN
admet-843	184	11	)	)	PUNCT
admet-843	184	12	(	(	PUNCT
admet-843	184	13	2020	2020	NUM
admet-843	184	14	)	)	PUNCT
admet-843	184	15	425	425	NUM
admet-843	184	16	-	-	SYM
admet-843	184	17	436	436	NUM
admet-843	184	18	434	434	NUM
admet-843	184	19	references	reference	NOUN
admet-843	184	20	[	[	X
admet-843	184	21	1	1	NUM
admet-843	184	22	]	]	PUNCT
admet-843	184	23	r.	r.	PROPN
admet-843	184	24	rebelo	rebelo	PROPN
admet-843	184	25	,	,	PUNCT
admet-843	184	26	m.	m.	NOUN
admet-843	184	27	fernandes	fernandes	PROPN
admet-843	184	28	,	,	PUNCT
admet-843	184	29	r.	r.	PROPN
admet-843	184	30	fangueiro	fangueiro	PROPN
admet-843	184	31	.	.	PUNCT
admet-843	185	1	biopolymers	biopolymer	NOUN
admet-843	185	2	in	in	ADP
admet-843	185	3	medical	medical	ADJ
admet-843	185	4	implants	implant	NOUN
admet-843	185	5	:	:	PUNCT
admet-843	185	6	a	a	DET
admet-843	185	7	brief	brief	ADJ
admet-843	185	8	review	review	NOUN
admet-843	185	9	.	.	PUNCT
admet-843	186	1	procedia	procedia	PROPN
admet-843	186	2	engineering	engineer	VERB
admet-843	186	3	200	200	NUM
admet-843	186	4	(	(	PUNCT
admet-843	186	5	2017	2017	NUM
admet-843	186	6	)	)	PUNCT
admet-843	186	7	236–243	236–243	NUM
admet-843	186	8	.	.	PUNCT
admet-843	187	1	[	[	X
admet-843	187	2	2	2	NUM
admet-843	187	3	]	]	PUNCT
admet-843	187	4	i.	i.	NOUN
admet-843	187	5	manavitehrani	manavitehrani	PROPN
admet-843	187	6	,	,	PUNCT
admet-843	187	7	a.	a.	NOUN
admet-843	187	8	fathi	fathi	PROPN
admet-843	187	9	,	,	PUNCT
admet-843	187	10	h.	h.	PROPN
admet-843	187	11	badr	badr	PROPN
admet-843	187	12	,	,	PUNCT
admet-843	187	13	s.	s.	PROPN
admet-843	187	14	daly	daly	PROPN
admet-843	187	15	,	,	PUNCT
admet-843	187	16	a.	a.	PROPN
admet-843	187	17	negahi	negahi	PROPN
admet-843	187	18	shirazi	shirazi	PROPN
admet-843	187	19	,	,	PUNCT
admet-843	187	20	f.	f.	PROPN
admet-843	187	21	dehghani	dehghani	PROPN
admet-843	187	22	.	.	PUNCT
admet-843	188	1	biomedical	biomedical	ADJ
admet-843	188	2	applications	application	NOUN
admet-843	188	3	of	of	ADP
admet-843	188	4	biodegradable	biodegradable	ADJ
admet-843	188	5	polyesters	polyester	NOUN
admet-843	188	6	.	.	PUNCT
admet-843	189	1	polymers	polymer	NOUN
admet-843	189	2	(	(	PUNCT
admet-843	189	3	basel	basel	PROPN
admet-843	189	4	)	)	PUNCT
admet-843	189	5	8	8	NUM
admet-843	189	6	(	(	PUNCT
admet-843	189	7	2016	2016	NUM
admet-843	189	8	)	)	PUNCT
admet-843	189	9	20	20	NUM
admet-843	189	10	.	.	PUNCT
admet-843	190	1	doi	doi	NOUN
admet-843	190	2	:	:	PUNCT
admet-843	190	3	https://doi.org/10.3390/polym8010020	https://doi.org/10.3390/polym8010020	VERB
admet-843	190	4	.	.	PUNCT
admet-843	191	1	[	[	X
admet-843	191	2	3	3	X
admet-843	191	3	]	]	X
admet-843	191	4	g.	g.	NOUN
admet-843	191	5	gorrasi	gorrasi	PROPN
admet-843	191	6	,	,	PUNCT
admet-843	191	7	r.	r.	PROPN
admet-843	191	8	pantani	pantani	PROPN
admet-843	191	9	.	.	PUNCT
admet-843	192	1	hydrolysis	hydrolysis	NOUN
admet-843	192	2	and	and	CCONJ
admet-843	192	3	biodegradation	biodegradation	NOUN
admet-843	192	4	of	of	ADP
admet-843	192	5	poly	poly	ADJ
admet-843	192	6	(	(	PUNCT
admet-843	192	7	lactic	lactic	ADJ
admet-843	192	8	acid	acid	NOUN
admet-843	192	9	)	)	PUNCT
admet-843	192	10	.	.	PUNCT
admet-843	193	1	advances	advance	NOUN
admet-843	193	2	in	in	ADP
admet-843	193	3	polymer	polymer	NOUN
admet-843	193	4	science	science	NOUN
admet-843	193	5	279	279	NUM
admet-843	193	6	(	(	PUNCT
admet-843	193	7	2018	2018	NUM
admet-843	193	8	)	)	PUNCT
admet-843	193	9	119	119	NUM
admet-843	193	10	-	-	SYM
admet-843	193	11	151	151	NUM
admet-843	193	12	.	.	PUNCT
admet-843	194	1	doi	doi	NOUN
admet-843	194	2	:	:	PUNCT
admet-843	194	3	https://doi.org/10.1007/12_2016_12	https://doi.org/10.1007/12_2016_12	PROPN
admet-843	194	4	.	.	PUNCT
admet-843	195	1	[	[	X
admet-843	195	2	4	4	NUM
admet-843	195	3	]	]	PUNCT
admet-843	195	4	m.	m.	NOUN
admet-843	195	5	savioli	savioli	PROPN
admet-843	195	6	lopes	lopes	PROPN
admet-843	195	7	,	,	PUNCT
admet-843	195	8	a.l	a.l	PROPN
admet-843	195	9	.	.	PROPN
admet-843	195	10	jardini	jardini	PROPN
admet-843	195	11	,	,	PUNCT
admet-843	195	12	r.	r.	PROPN
admet-843	195	13	maciel	maciel	PROPN
admet-843	195	14	filho	filho	PROPN
admet-843	195	15	.	.	PUNCT
admet-843	196	1	poly	poly	ADJ
admet-843	196	2	(	(	PUNCT
admet-843	196	3	lactic	lactic	ADJ
admet-843	196	4	acid	acid	NOUN
admet-843	196	5	)	)	PUNCT
admet-843	196	6	production	production	NOUN
admet-843	196	7	for	for	ADP
admet-843	196	8	tissue	tissue	NOUN
admet-843	196	9	engineering	engineering	NOUN
admet-843	196	10	applications	application	NOUN
admet-843	196	11	.	.	PUNCT
admet-843	197	1	procedia	procedia	PROPN
admet-843	197	2	engineering	engineer	VERB
admet-843	197	3	42	42	NUM
admet-843	197	4	(	(	PUNCT
admet-843	197	5	2012	2012	NUM
admet-843	197	6	)	)	PUNCT
admet-843	197	7	1402	1402	NUM
admet-843	197	8	–	–	PUNCT
admet-843	197	9	1413	1413	NUM
admet-843	197	10	.	.	PUNCT
admet-843	198	1	doi	doi	NOUN
admet-843	198	2	:	:	PUNCT
admet-843	198	3	https://doi.org/10.1016/j.proeng.2012.07.534	https://doi.org/10.1016/j.proeng.2012.07.534	ADJ
admet-843	198	4	.	.	PUNCT
admet-843	199	1	[	[	X
admet-843	199	2	5	5	X
admet-843	199	3	]	]	PUNCT
admet-843	199	4	t.	t.	NOUN
admet-843	199	5	casalini	casalini	PROPN
admet-843	199	6	,	,	PUNCT
admet-843	199	7	f.	f.	PROPN
admet-843	199	8	rossi	rossi	PROPN
admet-843	199	9	,	,	PUNCT
admet-843	199	10	a.	a.	PROPN
admet-843	199	11	castrovinci	castrovinci	PROPN
admet-843	199	12	,	,	PUNCT
admet-843	199	13	g.	g.	PROPN
admet-843	199	14	perale	perale	PROPN
admet-843	199	15	.	.	PUNCT
admet-843	200	1	a	a	DET
admet-843	200	2	perspective	perspective	NOUN
admet-843	200	3	on	on	ADP
admet-843	200	4	polylactic	polylactic	ADJ
admet-843	200	5	acid	acid	NOUN
admet-843	200	6	-	-	PUNCT
admet-843	200	7	based	base	VERB
admet-843	200	8	polymers	polymer	NOUN
admet-843	200	9	use	use	VERB
admet-843	200	10	for	for	ADP
admet-843	200	11	nanoparticles	nanoparticle	NOUN
admet-843	200	12	synthesis	synthesis	NOUN
admet-843	200	13	and	and	CCONJ
admet-843	200	14	applications	application	NOUN
admet-843	200	15	.	.	PUNCT
admet-843	201	1	frontiers	frontier	NOUN
admet-843	201	2	in	in	ADP
admet-843	201	3	bioengineering	bioengineering	NOUN
admet-843	201	4	and	and	CCONJ
admet-843	201	5	biotechnology	biotechnology	NOUN
admet-843	201	6	7	7	NUM
admet-843	201	7	(	(	PUNCT
admet-843	201	8	219	219	NUM
admet-843	201	9	)	)	PUNCT
admet-843	201	10	259	259	NUM
admet-843	201	11	.	.	PUNCT
admet-843	202	1	doi	doi	NOUN
admet-843	202	2	:	:	PUNCT
admet-843	202	3	https://doi.org/10.3389/fbioe.2019.00259	https://doi.org/10.3389/fbioe.2019.00259	X
admet-843	202	4	.	.	PUNCT
admet-843	203	1	[	[	X
admet-843	203	2	6	6	NUM
admet-843	203	3	]	]	PUNCT
admet-843	203	4	s.	s.	PROPN
admet-843	203	5	shakeri	shakeri	PROPN
admet-843	203	6	,	,	PUNCT
admet-843	203	7	m.	m.	NOUN
admet-843	203	8	ashrafizadeh	ashrafizadeh	PROPN
admet-843	203	9	,	,	PUNCT
admet-843	203	10	a.	a.	NOUN
admet-843	203	11	zarrabi	zarrabi	PROPN
admet-843	203	12	,	,	PUNCT
admet-843	203	13	r.	r.	PROPN
admet-843	203	14	roghanian	roghanian	PROPN
admet-843	203	15	,	,	PUNCT
admet-843	203	16	e.g.	e.g.	ADV
admet-843	203	17	afshar	afshar	ADJ
admet-843	203	18	,	,	PUNCT
admet-843	203	19	a.	a.	NOUN
admet-843	203	20	pardakhty	pardakhty	NOUN
admet-843	203	21	,	,	PUNCT
admet-843	203	22	r.	r.	PROPN
admet-843	203	23	mohammadinejad	mohammadinejad	PROPN
admet-843	203	24	,	,	PUNCT
admet-843	203	25	a.	a.	PROPN
admet-843	203	26	kumar	kumar	PROPN
admet-843	203	27	,	,	PUNCT
admet-843	203	28	v.k	v.k	PROPN
admet-843	203	29	.	.	PROPN
admet-843	203	30	thakur	thakur	PROPN
admet-843	203	31	.	.	PUNCT
admet-843	204	1	multifunctional	multifunctional	ADJ
admet-843	204	2	polymeric	polymeric	ADJ
admet-843	204	3	nanoplatforms	nanoplatform	NOUN
admet-843	204	4	for	for	ADP
admet-843	204	5	brain	brain	NOUN
admet-843	204	6	diseases	disease	NOUN
admet-843	204	7	diagnosis	diagnosis	NOUN
admet-843	204	8	,	,	PUNCT
admet-843	204	9	therapy	therapy	NOUN
admet-843	204	10	and	and	CCONJ
admet-843	204	11	theranostics	theranostic	NOUN
admet-843	204	12	.	.	PUNCT
admet-843	205	1	biomedicines	biomedicine	VERB
admet-843	205	2	8	8	NUM
admet-843	205	3	(	(	PUNCT
admet-843	205	4	2020	2020	NUM
admet-843	205	5	)	)	PUNCT
admet-843	205	6	13	13	NUM
admet-843	205	7	.	.	PUNCT
admet-843	206	1	doi	doi	NOUN
admet-843	206	2	:	:	PUNCT
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admet-843	206	4	.	.	PUNCT
admet-843	207	1	[	[	X
admet-843	207	2	7	7	X
admet-843	207	3	]	]	X
admet-843	207	4	m.a	m.a	PROPN
admet-843	207	5	.	.	PROPN
admet-843	207	6	elsawy	elsawy	PROPN
admet-843	207	7	,	,	PUNCT
admet-843	207	8	k.h	k.h	PROPN
admet-843	207	9	.	.	PROPN
admet-843	207	10	kim	kim	PROPN
admet-843	207	11	,	,	PUNCT
admet-843	207	12	j.w	j.w	PROPN
admet-843	207	13	.	.	PROPN
admet-843	207	14	park	park	PROPN
admet-843	207	15	,	,	PUNCT
admet-843	207	16	a.	a.	NOUN
admet-843	207	17	deep	deep	ADJ
admet-843	207	18	.	.	PUNCT
admet-843	208	1	hydrolytic	hydrolytic	ADJ
admet-843	208	2	degradation	degradation	NOUN
admet-843	208	3	of	of	ADP
admet-843	208	4	polylactic	polylactic	ADJ
admet-843	208	5	acid	acid	NOUN
admet-843	208	6	(	(	PUNCT
admet-843	208	7	pla	pla	NOUN
admet-843	208	8	)	)	PUNCT
admet-843	208	9	and	and	CCONJ
admet-843	208	10	its	its	PRON
admet-843	208	11	composites	composite	NOUN
admet-843	208	12	.	.	PUNCT
admet-843	209	1	renewable	renewable	ADJ
admet-843	209	2	and	and	CCONJ
admet-843	209	3	sustainable	sustainable	ADJ
admet-843	209	4	energy	energy	NOUN
admet-843	209	5	reviews	review	NOUN
admet-843	209	6	79	79	NUM
admet-843	209	7	(	(	PUNCT
admet-843	209	8	2017	2017	NUM
admet-843	209	9	)	)	PUNCT
admet-843	209	10	1346	1346	NUM
admet-843	209	11	-	-	SYM
admet-843	209	12	1352	1352	NUM
admet-843	209	13	.	.	PUNCT
admet-843	210	1	https://doi.org/10.1016/j.rser.2017.05.143	https://doi.org/10.1016/j.rser.2017.05.143	NOUN
admet-843	210	2	.	.	PUNCT
admet-843	211	1	[	[	X
admet-843	211	2	8	8	NUM
admet-843	211	3	]	]	X
admet-843	211	4	d.l	d.l	PROPN
admet-843	211	5	.	.	PROPN
admet-843	211	6	roman	roman	PROPN
admet-843	211	7	,	,	PUNCT
admet-843	211	8	m.	m.	NOUN
admet-843	211	9	roman	roman	NOUN
admet-843	211	10	,	,	PUNCT
admet-843	211	11	c.	c.	PROPN
admet-843	211	12	som	som	PROPN
admet-843	211	13	,	,	PUNCT
admet-843	211	14	m.	m.	NOUN
admet-843	211	15	schmutz	schmutz	PROPN
admet-843	211	16	,	,	PUNCT
admet-843	211	17	e.	e.	PROPN
admet-843	211	18	hernandez	hernandez	PROPN
admet-843	211	19	,	,	PUNCT
admet-843	211	20	p.	p.	PROPN
admet-843	211	21	wick	wick	PROPN
admet-843	211	22	,	,	PUNCT
admet-843	211	23	t.	t.	NOUN
admet-843	211	24	casalini	casalini	PROPN
admet-843	211	25	,	,	PUNCT
admet-843	211	26	g.	g.	PROPN
admet-843	211	27	perale	perale	PROPN
admet-843	211	28	,	,	PUNCT
admet-843	211	29	v.	v.	ADP
admet-843	211	30	ostafe	ostafe	NOUN
admet-843	211	31	,	,	PUNCT
admet-843	211	32	a.	a.	NOUN
admet-843	211	33	isvoran	isvoran	NOUN
admet-843	211	34	.	.	PUNCT
admet-843	212	1	computational	computational	ADJ
admet-843	212	2	assessment	assessment	NOUN
admet-843	212	3	of	of	ADP
admet-843	212	4	the	the	DET
admet-843	212	5	pharmacological	pharmacological	ADJ
admet-843	212	6	profiles	profile	NOUN
admet-843	212	7	of	of	ADP
admet-843	212	8	degradation	degradation	NOUN
admet-843	212	9	products	product	NOUN
admet-843	212	10	of	of	ADP
admet-843	212	11	chitosan	chitosan	NOUN
admet-843	212	12	.	.	PUNCT
admet-843	213	1	frontiers	frontier	NOUN
admet-843	213	2	in	in	ADP
admet-843	213	3	bioengineering	bioengineering	NOUN
admet-843	213	4	and	and	CCONJ
admet-843	213	5	biotechnology	biotechnology	NOUN
admet-843	213	6	7	7	NUM
admet-843	213	7	(	(	PUNCT
admet-843	213	8	2019	2019	NUM
admet-843	213	9	)	)	PUNCT
admet-843	213	10	214	214	NUM
admet-843	213	11	.	.	PUNCT
admet-843	214	1	doi	doi	NOUN
admet-843	214	2	:	:	PUNCT
admet-843	214	3	https://doi.org/10.3389/fbioe.2019.00214	https://doi.org/10.3389/fbioe.2019.00214	PROPN
admet-843	214	4	.	.	PUNCT
admet-843	215	1	[	[	X
admet-843	215	2	9	9	NUM
admet-843	215	3	]	]	X
admet-843	215	4	d.f	d.f	PROPN
admet-843	215	5	.	.	PROPN
admet-843	215	6	veber	veber	PROPN
admet-843	215	7	,	,	PUNCT
admet-843	215	8	s.r	s.r	PROPN
admet-843	215	9	.	.	PROPN
admet-843	215	10	johnson	johnson	PROPN
admet-843	215	11	,	,	PUNCT
admet-843	215	12	h.y	h.y	PROPN
admet-843	215	13	.	.	PROPN
admet-843	215	14	cheng	cheng	PROPN
admet-843	215	15	,	,	PUNCT
admet-843	215	16	b.r	b.r	PROPN
admet-843	215	17	.	.	PROPN
admet-843	215	18	smith	smith	PROPN
admet-843	215	19	,	,	PUNCT
admet-843	215	20	k.w	k.w	PROPN
admet-843	215	21	.	.	PROPN
admet-843	215	22	ward	ward	PROPN
admet-843	215	23	,	,	PUNCT
admet-843	215	24	k.d	k.d	PROPN
admet-843	215	25	.	.	PROPN
admet-843	215	26	kopple	kopple	PROPN
admet-843	215	27	.	.	PUNCT
admet-843	216	1	molecular	molecular	ADJ
admet-843	216	2	properties	property	NOUN
admet-843	216	3	that	that	PRON
admet-843	216	4	influence	influence	VERB
admet-843	216	5	the	the	DET
admet-843	216	6	oral	oral	ADJ
admet-843	216	7	bioavailability	bioavailability	NOUN
admet-843	216	8	of	of	ADP
admet-843	216	9	drug	drug	NOUN
admet-843	216	10	candidates	candidate	NOUN
admet-843	216	11	.	.	PUNCT
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admet-843	217	6	(	(	PUNCT
admet-843	217	7	2002	2002	NUM
admet-843	217	8	)	)	PUNCT
admet-843	217	9	26152623	26152623	NUM
admet-843	217	10	.	.	PUNCT
admet-843	218	1	doi	doi	NOUN
admet-843	218	2	:	:	PUNCT
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admet-843	219	1	[	[	X
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admet-843	220	8	.	.	PUNCT
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admet-843	221	7	)	)	PUNCT
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admet-843	221	12	.	.	PUNCT
admet-843	222	1	doi	doi	PROPN
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admet-843	223	2	11	11	NUM
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admet-843	224	3	,	,	PUNCT
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admet-843	224	6	,	,	PUNCT
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admet-843	224	11	,	,	PUNCT
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admet-843	224	14	.	.	PUNCT
admet-843	225	1	[	[	X
admet-843	225	2	12	12	NUM
admet-843	225	3	]	]	X
admet-843	225	4	r.p	r.p	PROPN
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admet-843	225	19	,	,	PUNCT
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admet-843	225	23	.	.	PUNCT
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admet-843	226	8	)	)	PUNCT
admet-843	226	9	.	.	PUNCT
admet-843	227	1	recent	recent	ADJ
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admet-843	227	7	(	(	PUNCT
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admet-843	227	9	)	)	PUNCT
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admet-843	227	11	-	-	SYM
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admet-843	227	13	.	.	PUNCT
admet-843	228	1	doi	doi	NOUN
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admet-843	228	4	.	.	PUNCT
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admet-843	229	2	13	13	NUM
admet-843	229	3	]	]	PUNCT
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admet-843	230	6	(	(	PUNCT
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admet-843	230	8	)	)	PUNCT
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admet-843	230	10	.	.	PUNCT
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admet-843	233	4	(	(	PUNCT
admet-843	233	5	2017	2017	NUM
admet-843	233	6	)	)	PUNCT
admet-843	233	7	42717	42717	NUM
admet-843	233	8	.	.	PUNCT
admet-843	234	1	doi	doi	NOUN
admet-843	234	2	:	:	PUNCT
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admet-843	234	4	.	.	PUNCT
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admet-843	235	17	.	.	PUNCT
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admet-843	236	9	(	(	PUNCT
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admet-843	236	11	)	)	PUNCT
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admet-843	236	13	.	.	PUNCT
admet-843	236	14	doi	doi	PROPN
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admet-843	236	17	.	.	PUNCT
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admet-843	237	2	16	16	NUM
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admet-843	240	2	.	.	PUNCT
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admet-843	243	12	-	-	SYM
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admet-843	243	14	.	.	PUNCT
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admet-843	246	5	https://doi.org/10.1021/ci034243x	https://doi.org/10.1021/ci034243x	NOUN
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admet-843	246	7	https://doi.org/10.1021/ci700257y	https://doi.org/10.1021/ci700257y	X
admet-843	246	8	admet	admet	PROPN
admet-843	246	9	&	&	CCONJ
admet-843	246	10	dmpk	dmpk	PROPN
admet-843	246	11	8(4	8(4	NOUN
admet-843	246	12	)	)	PUNCT
admet-843	246	13	(	(	PUNCT
admet-843	246	14	2020	2020	NUM
admet-843	246	15	)	)	PUNCT
admet-843	246	16	425	425	NUM
admet-843	246	17	-	-	SYM
admet-843	246	18	436	436	NUM
admet-843	246	19	admet	admet	NOUN
admet-843	246	20	profiles	profile	NOUN
admet-843	246	21	of	of	ADP
admet-843	246	22	oligomers	oligomer	NOUN
admet-843	246	23	of	of	ADP
admet-843	246	24	lactic	lactic	ADJ
admet-843	246	25	acid	acid	NOUN
admet-843	246	26	doi	doi	NOUN
admet-843	246	27	:	:	PUNCT
admet-843	246	28	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	NOUN
admet-843	246	29	435	435	NUM
admet-843	246	30	[	[	SYM
admet-843	246	31	18	18	NUM
admet-843	246	32	]	]	X
admet-843	246	33	f.	f.	PROPN
admet-843	246	34	cheng	cheng	PROPN
admet-843	246	35	,	,	PUNCT
admet-843	246	36	w.	w.	PROPN
admet-843	246	37	li	li	PROPN
admet-843	246	38	,	,	PUNCT
admet-843	246	39	y.	y.	PROPN
admet-843	246	40	zhou	zhou	PROPN
admet-843	246	41	,	,	PUNCT
admet-843	246	42	j.	j.	PROPN
admet-843	246	43	shen	shen	PROPN
admet-843	246	44	,	,	PUNCT
admet-843	246	45	z.	z.	PROPN
admet-843	246	46	wu	wu	PROPN
admet-843	246	47	,	,	PUNCT
admet-843	246	48	g.	g.	PROPN
admet-843	246	49	liu	liu	PROPN
admet-843	246	50	,	,	PUNCT
admet-843	246	51	p.w	p.w	PROPN
admet-843	246	52	.	.	PROPN
admet-843	246	53	lee	lee	PROPN
admet-843	246	54	,	,	PUNCT
admet-843	246	55	y.	y.	PROPN
admet-843	246	56	tang	tang	PROPN
admet-843	246	57	.	.	PUNCT
admet-843	247	1	admetsar	admetsar	ADJ
admet-843	247	2	:	:	PUNCT
admet-843	247	3	a	a	DET
admet-843	247	4	comprehensive	comprehensive	ADJ
admet-843	247	5	source	source	NOUN
admet-843	247	6	and	and	CCONJ
admet-843	247	7	free	free	ADJ
admet-843	247	8	tool	tool	NOUN
admet-843	247	9	for	for	ADP
admet-843	247	10	evaluating	evaluate	VERB
admet-843	247	11	chemical	chemical	ADJ
admet-843	247	12	admet	admet	NOUN
admet-843	247	13	properties	property	NOUN
admet-843	247	14	.	.	PUNCT
admet-843	248	1	journal	journal	PROPN
admet-843	248	2	of	of	ADP
admet-843	248	3	chemical	chemical	ADJ
admet-843	248	4	information	information	NOUN
admet-843	248	5	and	and	CCONJ
admet-843	248	6	modeling	model	VERB
admet-843	248	7	52	52	NUM
admet-843	248	8	(	(	PUNCT
admet-843	248	9	2012	2012	NUM
admet-843	248	10	)	)	PUNCT
admet-843	248	11	3099	3099	NUM
admet-843	248	12	-	-	SYM
admet-843	248	13	3105	3105	NUM
admet-843	248	14	.	.	PUNCT
admet-843	249	1	doi	doi	NOUN
admet-843	249	2	:	:	PUNCT
admet-843	249	3	https://doi.org/10.1021/ci300367a	https://doi.org/10.1021/ci300367a	X
admet-843	249	4	.	.	PUNCT
admet-843	250	1	[	[	X
admet-843	250	2	19	19	NUM
admet-843	250	3	]	]	X
admet-843	250	4	h.	h.	PROPN
admet-843	250	5	yang	yang	PROPN
admet-843	250	6	,	,	PUNCT
admet-843	250	7	c.	c.	PROPN
admet-843	250	8	lou	lou	PROPN
admet-843	250	9	,	,	PUNCT
admet-843	250	10	l.	l.	PROPN
admet-843	250	11	sun	sun	PROPN
admet-843	250	12	,	,	PUNCT
admet-843	250	13	j.	j.	PROPN
admet-843	250	14	li	li	PROPN
admet-843	250	15	,	,	PUNCT
admet-843	250	16	y.	y.	PROPN
admet-843	250	17	cai	cai	PROPN
admet-843	250	18	,	,	PUNCT
admet-843	250	19	z.	z.	PROPN
admet-843	250	20	wang	wang	PROPN
admet-843	250	21	,	,	PUNCT
admet-843	250	22	w.	w.	PROPN
admet-843	250	23	li	li	PROPN
admet-843	250	24	,	,	PUNCT
admet-843	250	25	g.	g.	PROPN
admet-843	250	26	liu	liu	PROPN
admet-843	250	27	,	,	PUNCT
admet-843	250	28	y.	y.	PROPN
admet-843	250	29	tang	tang	PROPN
admet-843	250	30	.	.	PUNCT
admet-843	251	1	admetsar	admetsar	ADJ
admet-843	251	2	2.0	2.0	NUM
admet-843	251	3	:	:	PUNCT
admet-843	251	4	web	web	NOUN
admet-843	251	5	-	-	NOUN
admet-843	251	6	service	service	NOUN
admet-843	251	7	for	for	ADP
admet-843	251	8	prediction	prediction	NOUN
admet-843	251	9	and	and	CCONJ
admet-843	251	10	optimization	optimization	NOUN
admet-843	251	11	of	of	ADP
admet-843	251	12	chemical	chemical	ADJ
admet-843	251	13	admet	admet	PROPN
admet-843	251	14	properties	property	NOUN
admet-843	251	15	.	.	PUNCT
admet-843	252	1	bioinformatics	bioinformatic	NOUN
admet-843	252	2	35	35	NUM
admet-843	252	3	(	(	PUNCT
admet-843	252	4	2019	2019	NUM
admet-843	252	5	)	)	PUNCT
admet-843	252	6	1067–1069	1067–1069	NUM
admet-843	252	7	.	.	PUNCT
admet-843	253	1	doi	doi	NOUN
admet-843	253	2	:	:	PUNCT
admet-843	253	3	https://doi.org/10.1093/bioinformatics/bty707	https://doi.org/10.1093/bioinformatics/bty707	NOUN
admet-843	253	4	.	.	PUNCT
admet-843	254	1	[	[	X
admet-843	254	2	20	20	NUM
admet-843	254	3	]	]	X
admet-843	254	4	r.c	r.c	PROPN
admet-843	254	5	.	.	PROPN
admet-843	254	6	braga	braga	PROPN
admet-843	254	7	,	,	PUNCT
admet-843	254	8	v.m	v.m	PROPN
admet-843	254	9	.	.	PROPN
admet-843	254	10	alves	alves	PROPN
admet-843	254	11	,	,	PUNCT
admet-843	254	12	e.n	e.n	PROPN
admet-843	254	13	.	.	PROPN
admet-843	254	14	muratov	muratov	PROPN
admet-843	254	15	,	,	PUNCT
admet-843	254	16	j.	j.	PROPN
admet-843	254	17	strickland	strickland	PROPN
admet-843	254	18	,	,	PUNCT
admet-843	254	19	n.	n.	PROPN
admet-843	254	20	kleinstreuer	kleinstreuer	PROPN
admet-843	254	21	,	,	PUNCT
admet-843	254	22	a.	a.	PROPN
admet-843	254	23	trospsha	trospsha	PROPN
admet-843	254	24	,	,	PUNCT
admet-843	254	25	c.h	c.h	PROPN
admet-843	254	26	.	.	PROPN
admet-843	254	27	andrade	andrade	PROPN
admet-843	254	28	.	.	PUNCT
admet-843	255	1	predskin	predskin	PROPN
admet-843	255	2	:	:	PUNCT
admet-843	255	3	a	a	DET
admet-843	255	4	fast	fast	ADJ
admet-843	255	5	and	and	CCONJ
admet-843	255	6	reliable	reliable	ADJ
admet-843	255	7	web	web	NOUN
admet-843	255	8	application	application	NOUN
admet-843	255	9	to	to	PART
admet-843	255	10	assess	assess	VERB
admet-843	255	11	skin	skin	NOUN
admet-843	255	12	sensitization	sensitization	NOUN
admet-843	255	13	effect	effect	NOUN
admet-843	255	14	of	of	ADP
admet-843	255	15	chemicals	chemical	NOUN
admet-843	255	16	.	.	PUNCT
admet-843	256	1	journal	journal	PROPN
admet-843	256	2	of	of	ADP
admet-843	256	3	chemical	chemical	ADJ
admet-843	256	4	information	information	NOUN
admet-843	256	5	and	and	CCONJ
admet-843	256	6	modeling	model	VERB
admet-843	256	7	57	57	NUM
admet-843	256	8	(	(	PUNCT
admet-843	256	9	2017	2017	NUM
admet-843	256	10	)	)	PUNCT
admet-843	256	11	1013	1013	NUM
admet-843	256	12	-	-	SYM
admet-843	256	13	1017	1017	NUM
admet-843	256	14	.	.	PUNCT
admet-843	257	1	doi	doi	NOUN
admet-843	257	2	:	:	PUNCT
admet-843	257	3	https://doi.org/10.1021/acs.jcim.7b00194	https://doi.org/10.1021/acs.jcim.7b00194	X
admet-843	257	4	.	.	PUNCT
admet-843	258	1	[	[	X
admet-843	258	2	21	21	NUM
admet-843	258	3	]	]	X
admet-843	258	4	v.m	v.m	PROPN
admet-843	258	5	.	.	PROPN
admet-843	258	6	alves	alves	PROPN
admet-843	258	7	,	,	PUNCT
admet-843	258	8	s.j	s.j	PROPN
admet-843	258	9	.	.	PROPN
admet-843	258	10	capuzzi	capuzzi	PROPN
admet-843	258	11	,	,	PUNCT
admet-843	258	12	r.c	r.c	PROPN
admet-843	258	13	.	.	PROPN
admet-843	258	14	braga	braga	PROPN
admet-843	258	15	,	,	PUNCT
admet-843	258	16	j.v.b	j.v.b	PROPN
admet-843	258	17	.	.	PUNCT
admet-843	258	18	borba	borba	PROPN
admet-843	258	19	,	,	PUNCT
admet-843	258	20	a.c	a.c	PROPN
admet-843	258	21	.	.	PROPN
admet-843	258	22	silva	silva	PROPN
admet-843	258	23	,	,	PUNCT
admet-843	258	24	t.	t.	PROPN
admet-843	258	25	luechtefeld	luechtefeld	PROPN
admet-843	258	26	,	,	PUNCT
admet-843	258	27	t.	t.	PROPN
admet-843	258	28	hartung	hartung	PROPN
admet-843	258	29	,	,	PUNCT
admet-843	258	30	c.h	c.h	PROPN
admet-843	258	31	.	.	PROPN
admet-843	258	32	andrade	andrade	PROPN
admet-843	258	33	,	,	PUNCT
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admet-843	258	35	.	.	PROPN
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admet-843	258	37	,	,	PUNCT
admet-843	258	38	a.	a.	NOUN
admet-843	258	39	tropsha	tropsha	PROPN
admet-843	258	40	.	.	PUNCT
admet-843	259	1	a	a	DET
admet-843	259	2	perspective	perspective	NOUN
admet-843	259	3	and	and	CCONJ
admet-843	259	4	a	a	DET
admet-843	259	5	new	new	ADJ
admet-843	259	6	integrated	integrated	ADJ
admet-843	259	7	computational	computational	ADJ
admet-843	259	8	strategy	strategy	NOUN
admet-843	259	9	for	for	ADP
admet-843	259	10	skin	skin	NOUN
admet-843	259	11	sensitization	sensitization	NOUN
admet-843	259	12	assessment	assessment	NOUN
admet-843	259	13	.	.	PUNCT
admet-843	260	1	acs	acs	PROPN
admet-843	260	2	sustainable	sustainable	ADJ
admet-843	260	3	chemistry	chemistry	NOUN
admet-843	260	4	&	&	CCONJ
admet-843	260	5	engineering	engineering	NOUN
admet-843	260	6	6	6	NUM
admet-843	260	7	(	(	PUNCT
admet-843	260	8	2018	2018	NUM
admet-843	260	9	)	)	PUNCT
admet-843	260	10	2845	2845	NUM
admet-843	260	11	-	-	SYM
admet-843	260	12	2859	2859	NUM
admet-843	260	13	.	.	PUNCT
admet-843	261	1	https://doi.org/10.1021/acssuschemeng.7b04220	https://doi.org/10.1021/acssuschemeng.7b04220	NOUN
admet-843	261	2	.	.	PUNCT
admet-843	262	1	[	[	X
admet-843	262	2	22	22	NUM
admet-843	262	3	]	]	PUNCT
admet-843	262	4	k.	k.	PROPN
admet-843	262	5	kolsek	kolsek	PROPN
admet-843	262	6	,	,	PUNCT
admet-843	262	7	j.	j.	PROPN
admet-843	262	8	mavri	mavri	PROPN
admet-843	262	9	,	,	PUNCT
admet-843	262	10	m.	m.	NOUN
admet-843	262	11	sollner	sollner	PROPN
admet-843	262	12	dolenc	dolenc	PROPN
admet-843	262	13	,	,	PUNCT
admet-843	262	14	s.	s.	PROPN
admet-843	262	15	gobec	gobec	PROPN
admet-843	262	16	,	,	PUNCT
admet-843	262	17	s.	s.	PROPN
admet-843	262	18	turk	turk	PROPN
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admet-843	263	1	endocrine	endocrine	PROPN
admet-843	263	2	disruptome	disruptome	VERB
admet-843	263	3	an	an	DET
admet-843	263	4	open	open	ADJ
admet-843	263	5	source	source	NOUN
admet-843	263	6	prediction	prediction	NOUN
admet-843	263	7	tool	tool	NOUN
admet-843	263	8	for	for	ADP
admet-843	263	9	assessing	assess	VERB
admet-843	263	10	endocrine	endocrine	ADJ
admet-843	263	11	disruption	disruption	NOUN
admet-843	263	12	potential	potential	NOUN
admet-843	263	13	through	through	ADP
admet-843	263	14	nuclear	nuclear	ADJ
admet-843	263	15	receptor	receptor	NOUN
admet-843	263	16	binding	bind	VERB
admet-843	263	17	.	.	PUNCT
admet-843	264	1	journal	journal	PROPN
admet-843	264	2	of	of	ADP
admet-843	264	3	chemical	chemical	ADJ
admet-843	264	4	information	information	NOUN
admet-843	264	5	and	and	CCONJ
admet-843	264	6	modeling	model	VERB
admet-843	264	7	54	54	NUM
admet-843	264	8	(	(	PUNCT
admet-843	264	9	2014	2014	NUM
admet-843	264	10	)	)	PUNCT
admet-843	264	11	1254	1254	NUM
admet-843	264	12	-	-	SYM
admet-843	264	13	1267	1267	NUM
admet-843	264	14	.	.	PUNCT
admet-843	265	1	doi	doi	NOUN
admet-843	265	2	:	:	PUNCT
admet-843	265	3	https://doi.org/10.1021/ci400649p	https://doi.org/10.1021/ci400649p	ADJ
admet-843	265	4	.	.	PUNCT
admet-843	266	1	[	[	X
admet-843	266	2	23	23	NUM
admet-843	266	3	]	]	X
admet-843	266	4	g.	g.	PROPN
admet-843	266	5	patlewicz	patlewicz	PROPN
admet-843	266	6	,	,	PUNCT
admet-843	266	7	n.	n.	PROPN
admet-843	266	8	jeliazkova	jeliazkova	PROPN
admet-843	266	9	,	,	PUNCT
admet-843	266	10	r.j	r.j	PROPN
admet-843	266	11	.	.	PROPN
admet-843	266	12	safford	safford	PROPN
admet-843	266	13	,	,	PUNCT
admet-843	266	14	a.p	a.p	PROPN
admet-843	266	15	.	.	PROPN
admet-843	266	16	worth	worth	PROPN
admet-843	266	17	,	,	PUNCT
admet-843	266	18	b.	b.	PROPN
admet-843	266	19	aleksiev	aleksiev	ADV
admet-843	266	20	.	.	PUNCT
admet-843	267	1	an	an	DET
admet-843	267	2	evaluation	evaluation	NOUN
admet-843	267	3	of	of	ADP
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admet-843	267	5	implementation	implementation	NOUN
admet-843	267	6	of	of	ADP
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admet-843	267	8	cramer	cramer	PROPN
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admet-843	267	10	scheme	scheme	NOUN
admet-843	267	11	in	in	ADP
admet-843	267	12	the	the	DET
admet-843	267	13	toxtree	toxtree	ADJ
admet-843	267	14	software	software	NOUN
admet-843	267	15	.	.	PUNCT
admet-843	268	1	sar	sar	PROPN
admet-843	268	2	nd	nd	PROPN
admet-843	268	3	qsar	qsar	PROPN
admet-843	268	4	in	in	ADP
admet-843	268	5	environmental	environmental	ADJ
admet-843	268	6	research	research	NOUN
admet-843	268	7	19	19	NUM
admet-843	268	8	(	(	PUNCT
admet-843	268	9	2008	2008	NUM
admet-843	268	10	)	)	PUNCT
admet-843	268	11	495	495	NUM
admet-843	268	12	-	-	SYM
admet-843	268	13	524	524	NUM
admet-843	268	14	.	.	PUNCT
admet-843	269	1	doi	doi	NOUN
admet-843	269	2	:	:	PUNCT
admet-843	269	3	https://doi.org/10.1080/10629360802083871	https://doi.org/10.1080/10629360802083871	ADJ
admet-843	269	4	.	.	PUNCT
admet-843	270	1	[	[	X
admet-843	270	2	24	24	NUM
admet-843	270	3	]	]	PUNCT
admet-843	270	4	l.	l.	PROPN
admet-843	270	5	zhang	zhang	PROPN
admet-843	270	6	,	,	PUNCT
admet-843	270	7	h.	h.	PROPN
admet-843	270	8	ai	ai	PROPN
admet-843	270	9	,	,	PUNCT
admet-843	270	10	w.	w.	PROPN
admet-843	270	11	chen	chen	PROPN
admet-843	270	12	,	,	PUNCT
admet-843	270	13	z.	z.	PROPN
admet-843	270	14	yin	yin	PROPN
admet-843	270	15	,	,	PUNCT
admet-843	270	16	h.	h.	PROPN
admet-843	270	17	hu	hu	PROPN
admet-843	270	18	,	,	PUNCT
admet-843	270	19	j.	j.	PROPN
admet-843	270	20	zhu	zhu	PROPN
admet-843	270	21	,	,	PUNCT
admet-843	270	22	j.	j.	PROPN
admet-843	270	23	zhao	zhao	PROPN
admet-843	270	24	,	,	PUNCT
admet-843	270	25	q.	q.	PROPN
admet-843	270	26	zhao	zhao	PROPN
admet-843	270	27	,	,	PUNCT
admet-843	270	28	h.	h.	PROPN
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admet-843	270	32	-	-	PUNCT
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admet-843	270	37	for	for	ADP
admet-843	270	38	predicting	predict	VERB
admet-843	270	39	the	the	DET
admet-843	270	40	carcinogenicity	carcinogenicity	NOUN
admet-843	270	41	of	of	ADP
admet-843	270	42	chemicals	chemical	NOUN
admet-843	270	43	using	use	VERB
admet-843	270	44	molecular	molecular	ADJ
admet-843	270	45	fingerprints	fingerprint	NOUN
admet-843	270	46	and	and	CCONJ
admet-843	270	47	ensemble	ensemble	ADJ
admet-843	270	48	learning	learning	NOUN
admet-843	270	49	methods	method	NOUN
admet-843	270	50	.	.	PUNCT
admet-843	271	1	scientific	scientific	ADJ
admet-843	271	2	reports	report	NOUN
admet-843	271	3	7	7	NUM
admet-843	271	4	(	(	PUNCT
admet-843	271	5	2017	2017	NUM
admet-843	271	6	)	)	PUNCT
admet-843	271	7	2118	2118	NUM
admet-843	271	8	.	.	PUNCT
admet-843	272	1	doi	doi	NOUN
admet-843	272	2	:	:	PUNCT
admet-843	272	3	https://doi.org/10.1038/s41598-017-02365-0	https://doi.org/10.1038/s41598-017-02365-0	NUM
admet-843	272	4	.	.	PUNCT
admet-843	273	1	[	[	X
admet-843	273	2	25	25	NUM
admet-843	273	3	]	]	PUNCT
admet-843	273	4	m.	m.	NOUN
admet-843	273	5	roman	roman	PROPN
admet-843	273	6	,	,	PUNCT
admet-843	273	7	d.l	d.l	PROPN
admet-843	273	8	.	.	PROPN
admet-843	273	9	roman	roman	PROPN
admet-843	273	10	,	,	PUNCT
admet-843	273	11	v.	v.	ADP
admet-843	273	12	ostafe	ostafe	NOUN
admet-843	273	13	,	,	PUNCT
admet-843	273	14	a.	a.	NOUN
admet-843	273	15	ciorsac	ciorsac	NOUN
admet-843	273	16	,	,	PUNCT
admet-843	273	17	a.	a.	NOUN
admet-843	273	18	isvoran	isvoran	NOUN
admet-843	273	19	.	.	PUNCT
admet-843	274	1	computational	computational	ADJ
admet-843	274	2	assessment	assessment	NOUN
admet-843	274	3	of	of	ADP
admet-843	274	4	pharmacokinetics	pharmacokinetic	NOUN
admet-843	274	5	and	and	CCONJ
admet-843	274	6	biological	biological	ADJ
admet-843	274	7	effects	effect	NOUN
admet-843	274	8	of	of	ADP
admet-843	274	9	some	some	DET
admet-843	274	10	anabolic	anabolic	NOUN
admet-843	274	11	and	and	CCONJ
admet-843	274	12	androgenic	androgenic	ADJ
admet-843	274	13	steroids	steroid	NOUN
admet-843	274	14	.	.	PUNCT
admet-843	275	1	pharmaceutical	pharmaceutical	NOUN
admet-843	275	2	research	research	NOUN
admet-843	275	3	35	35	NUM
admet-843	275	4	(	(	PUNCT
admet-843	275	5	2018	2018	NUM
admet-843	275	6	)	)	PUNCT
admet-843	275	7	41	41	NUM
admet-843	275	8	.	.	PUNCT
admet-843	276	1	doi	doi	NOUN
admet-843	276	2	:	:	PUNCT
admet-843	276	3	https://doi.org/10.1007/s11095-018-2353-1	https://doi.org/10.1007/s11095-018-2353-1	NUM
admet-843	276	4	.	.	PUNCT
admet-843	277	1	[	[	X
admet-843	277	2	26	26	NUM
admet-843	277	3	]	]	X
admet-843	277	4	v.m	v.m	PROPN
admet-843	277	5	.	.	PROPN
admet-843	277	6	alves	alves	PROPN
admet-843	277	7	,	,	PUNCT
admet-843	277	8	e.n	e.n	PROPN
admet-843	277	9	.	.	PROPN
admet-843	277	10	muratov	muratov	PROPN
admet-843	277	11	,	,	PUNCT
admet-843	277	12	a.	a.	NOUN
admet-843	277	13	zakharov	zakharov	PROPN
admet-843	277	14	,	,	PUNCT
admet-843	277	15	n.n	n.n	PROPN
admet-843	277	16	.	.	PROPN
admet-843	277	17	muratov	muratov	PROPN
admet-843	277	18	,	,	PUNCT
admet-843	277	19	c.h	c.h	PROPN
admet-843	277	20	.	.	PROPN
admet-843	277	21	andrade	andrade	PROPN
admet-843	277	22	,	,	PUNCT
admet-843	277	23	a.	a.	PROPN
admet-843	277	24	tropsha	tropsha	PROPN
admet-843	277	25	.	.	PUNCT
admet-843	277	26	chemical	chemical	NOUN
admet-843	277	27	toxicity	toxicity	NOUN
admet-843	277	28	prediction	prediction	NOUN
admet-843	277	29	for	for	ADP
admet-843	277	30	major	major	ADJ
admet-843	277	31	classes	class	NOUN
admet-843	277	32	of	of	ADP
admet-843	277	33	industrial	industrial	ADJ
admet-843	277	34	chemicals	chemical	NOUN
admet-843	277	35	:	:	PUNCT
admet-843	277	36	is	be	AUX
admet-843	277	37	it	it	PRON
admet-843	277	38	possible	possible	ADJ
admet-843	277	39	to	to	PART
admet-843	277	40	develop	develop	VERB
admet-843	277	41	universal	universal	ADJ
admet-843	277	42	models	model	NOUN
admet-843	277	43	covering	cover	VERB
admet-843	277	44	cosmetics	cosmetic	NOUN
admet-843	277	45	,	,	PUNCT
admet-843	277	46	drugs	drug	NOUN
admet-843	277	47	,	,	PUNCT
admet-843	277	48	and	and	CCONJ
admet-843	277	49	pesticides	pesticide	NOUN
admet-843	277	50	?	?	PUNCT
admet-843	277	51	.	.	PUNCT
admet-843	278	1	food	food	NOUN
admet-843	278	2	and	and	CCONJ
admet-843	278	3	chemical	chemical	NOUN
admet-843	278	4	toxicology	toxicology	NOUN
admet-843	278	5	112	112	NUM
admet-843	278	6	(	(	PUNCT
admet-843	278	7	2018	2018	NUM
admet-843	278	8	)	)	PUNCT
admet-843	278	9	526	526	NUM
admet-843	278	10	-	-	SYM
admet-843	278	11	534	534	NUM
admet-843	278	12	.	.	PUNCT
admet-843	279	1	doi	doi	NOUN
admet-843	279	2	:	:	PUNCT
admet-843	279	3	https://doi.org/10.1016/j.fct.2017.04.008	https://doi.org/10.1016/j.fct.2017.04.008	NOUN
admet-843	279	4	.	.	PUNCT
admet-843	280	1	[	[	X
admet-843	280	2	27	27	NUM
admet-843	280	3	]	]	PUNCT
admet-843	280	4	m.	m.	NOUN
admet-843	280	5	roman	roman	PROPN
admet-843	280	6	,	,	PUNCT
admet-843	280	7	d.l	d.l	PROPN
admet-843	280	8	.	.	PROPN
admet-843	280	9	roman	roman	PROPN
admet-843	280	10	,	,	PUNCT
admet-843	280	11	v.	v.	ADP
admet-843	280	12	ostafe	ostafe	NOUN
admet-843	280	13	,	,	PUNCT
admet-843	280	14	a.	a.	NOUN
admet-843	280	15	isvoran	isvoran	NOUN
admet-843	280	16	.	.	PUNCT
admet-843	281	1	computational	computational	ADJ
admet-843	281	2	assessment	assessment	NOUN
admet-843	281	3	of	of	ADP
admet-843	281	4	biological	biological	ADJ
admet-843	281	5	effects	effect	NOUN
admet-843	281	6	of	of	ADP
admet-843	281	7	methyl-,ethyl-	methyl-,ethyl-	PROPN
admet-843	281	8	,	,	PUNCT
admet-843	281	9	propyland	propyland	NOUN
admet-843	281	10	butyl	butyl	NOUN
admet-843	281	11	-	-	PUNCT
admet-843	281	12	parabens	paraben	NOUN
admet-843	281	13	.	.	PUNCT
admet-843	282	1	jsm	jsm	PROPN
admet-843	282	2	bioinformatics	bioinformatics	PROPN
admet-843	282	3	,	,	PUNCT
admet-843	282	4	genomics	genomic	NOUN
admet-843	282	5	and	and	CCONJ
admet-843	282	6	proteomics	proteomic	NOUN
admet-843	282	7	3	3	NUM
admet-843	282	8	(	(	PUNCT
admet-843	282	9	2018	2018	NUM
admet-843	282	10	)	)	PUNCT
admet-843	282	11	1029	1029	NUM
admet-843	282	12	.	.	PUNCT
admet-843	283	1	[	[	X
admet-843	283	2	28	28	NUM
admet-843	283	3	]	]	X
admet-843	283	4	i.m	i.m	PROPN
admet-843	283	5	.	.	PROPN
admet-843	283	6	gridan	gridan	PROPN
admet-843	283	7	,	,	PUNCT
admet-843	283	8	a.a	a.a	PROPN
admet-843	283	9	.	.	PROPN
admet-843	283	10	ciorsac	ciorsac	PROPN
admet-843	283	11	,	,	PUNCT
admet-843	283	12	a.	a.	NOUN
admet-843	283	13	isvoran	isvoran	NOUN
admet-843	283	14	.	.	PUNCT
admet-843	284	1	prediction	prediction	NOUN
admet-843	284	2	of	of	ADP
admet-843	284	3	adme	adme	NOUN
admet-843	284	4	-	-	PUNCT
admet-843	284	5	tox	tox	NOUN
admet-843	284	6	properties	property	NOUN
admet-843	284	7	and	and	CCONJ
admet-843	284	8	toxicological	toxicological	ADJ
admet-843	284	9	endpoints	endpoint	NOUN
admet-843	284	10	of	of	ADP
admet-843	284	11	triazole	triazole	ADJ
admet-843	284	12	fungicides	fungicide	NOUN
admet-843	284	13	used	use	VERB
admet-843	284	14	for	for	ADP
admet-843	284	15	cereals	cereal	NOUN
admet-843	284	16	protection	protection	NOUN
admet-843	284	17	.	.	PUNCT
admet-843	285	1	admet&dmpk	admet&dmpk	NOUN
admet-843	285	2	7	7	NUM
admet-843	285	3	(	(	PUNCT
admet-843	285	4	2019	2019	NUM
admet-843	285	5	)	)	PUNCT
admet-843	285	6	161	161	NUM
admet-843	285	7	-	-	SYM
admet-843	285	8	173	173	NUM
admet-843	285	9	.	.	PUNCT
admet-843	285	10	https://dx.doi.org/10.5599/admet.668	https://dx.doi.org/10.5599/admet.668	NOUN
admet-843	285	11	.	.	PUNCT
admet-843	286	1	[	[	X
admet-843	286	2	29	29	NUM
admet-843	286	3	]	]	PUNCT
admet-843	286	4	a.	a.	NOUN
admet-843	286	5	isvoran	isvoran	NOUN
admet-843	286	6	,	,	PUNCT
admet-843	286	7	a.	a.	NOUN
admet-843	286	8	ciorsac	ciorsac	NOUN
admet-843	286	9	,	,	PUNCT
admet-843	286	10	v.	v.	ADP
admet-843	286	11	ostafe	ostafe	NOUN
admet-843	286	12	.	.	PUNCT
admet-843	287	1	adme	adme	NOUN
admet-843	287	2	-	-	PUNCT
admet-843	287	3	tox	tox	NOUN
admet-843	287	4	profiling	profiling	NOUN
admet-843	287	5	of	of	ADP
admet-843	287	6	some	some	DET
admet-843	287	7	low	low	ADJ
admet-843	287	8	molecular	molecular	ADJ
admet-843	287	9	weight	weight	NOUN
admet-843	287	10	water	water	NOUN
admet-843	287	11	soluble	soluble	ADJ
admet-843	287	12	chitosan	chitosan	NOUN
admet-843	287	13	derivatives	derivative	NOUN
admet-843	287	14	.	.	PUNCT
admet-843	288	1	admet	admet	PROPN
admet-843	288	2	&	&	CCONJ
admet-843	288	3	dmpk	dmpk	PROPN
admet-843	288	4	5	5	NUM
admet-843	288	5	(	(	PUNCT
admet-843	288	6	2017	2017	NUM
admet-843	288	7	)	)	PUNCT
admet-843	288	8	192	192	NUM
admet-843	288	9	-	-	SYM
admet-843	288	10	200	200	NUM
admet-843	288	11	.	.	PUNCT
admet-843	289	1	https://doi.org/10.5599/admet.5.3.423	https://doi.org/10.5599/admet.5.3.423	NOUN
admet-843	289	2	.	.	PUNCT
admet-843	290	1	[	[	X
admet-843	290	2	30	30	NUM
admet-843	290	3	]	]	X
admet-843	290	4	r.c	r.c	PROPN
admet-843	290	5	.	.	PROPN
admet-843	290	6	braga	braga	PROPN
admet-843	290	7	,	,	PUNCT
admet-843	290	8	v.m	v.m	PROPN
admet-843	290	9	.	.	PROPN
admet-843	290	10	alves	alves	PROPN
admet-843	290	11	,	,	PUNCT
admet-843	290	12	m.f	m.f	PROPN
admet-843	290	13	.	.	PROPN
admet-843	290	14	silva	silva	PROPN
admet-843	290	15	,	,	PUNCT
admet-843	290	16	e.	e.	PROPN
admet-843	290	17	muratov	muratov	PROPN
admet-843	290	18	,	,	PUNCT
admet-843	290	19	d.	d.	PROPN
admet-843	290	20	fourches	fourches	PROPN
admet-843	290	21	,	,	PUNCT
admet-843	290	22	l.m	l.m	PROPN
admet-843	290	23	.	.	PROPN
admet-843	290	24	lião	lião	PROPN
admet-843	290	25	,	,	PUNCT
admet-843	290	26	a.	a.	NOUN
admet-843	290	27	tropsha	tropsha	PROPN
admet-843	290	28	,	,	PUNCT
admet-843	290	29	c.h	c.h	PROPN
admet-843	290	30	.	.	PROPN
admet-843	290	31	andrade	andrade	PROPN
admet-843	290	32	.	.	PUNCT
admet-843	291	1	predherg	predherg	PROPN
admet-843	291	2	:	:	PUNCT
admet-843	291	3	a	a	DET
admet-843	291	4	novel	novel	ADJ
admet-843	291	5	web	web	NOUN
admet-843	291	6	-	-	ADJ
admet-843	291	7	accessible	accessible	ADJ
admet-843	291	8	computational	computational	ADJ
admet-843	291	9	tool	tool	NOUN
admet-843	291	10	for	for	ADP
admet-843	291	11	predicting	predict	VERB
admet-843	291	12	cardiac	cardiac	ADJ
admet-843	291	13	toxicity	toxicity	NOUN
admet-843	291	14	.	.	PUNCT
admet-843	292	1	molecular	molecular	ADJ
admet-843	292	2	informatics	informatic	NOUN
admet-843	292	3	34	34	NUM
admet-843	292	4	(	(	PUNCT
admet-843	292	5	2015	2015	NUM
admet-843	292	6	)	)	PUNCT
admet-843	292	7	698	698	NUM
admet-843	292	8	-	-	SYM
admet-843	292	9	701	701	NUM
admet-843	292	10	.	.	PUNCT
admet-843	292	11	doi	doi	NOUN
admet-843	292	12	:	:	PUNCT
admet-843	292	13	https://doi.org/10.1002/minf.201500040	https://doi.org/10.1002/minf.201500040	X
admet-843	292	14	.	.	PUNCT
admet-843	293	1	[	[	X
admet-843	293	2	31	31	NUM
admet-843	293	3	]	]	X
admet-843	293	4	v.m	v.m	PROPN
admet-843	293	5	.	.	PROPN
admet-843	293	6	alves	alves	PROPN
admet-843	293	7	,	,	PUNCT
admet-843	293	8	r.c	r.c	PROPN
admet-843	293	9	.	.	PROPN
admet-843	293	10	braga	braga	PROPN
admet-843	293	11	,	,	PUNCT
admet-843	293	12	e.	e.	PROPN
admet-843	293	13	muratov	muratov	PROPN
admet-843	293	14	,	,	PUNCT
admet-843	293	15	c.h	c.h	PROPN
admet-843	293	16	.	.	PROPN
admet-843	293	17	andrade	andrade	PROPN
admet-843	293	18	.	.	PUNCT
admet-843	294	1	development	development	PROPN
admet-843	294	2	of	of	ADP
admet-843	294	3	web	web	NOUN
admet-843	294	4	and	and	CCONJ
admet-843	294	5	mobile	mobile	ADJ
admet-843	294	6	applications	application	NOUN
admet-843	294	7	for	for	ADP
admet-843	294	8	chemical	chemical	NOUN
admet-843	294	9	toxicity	toxicity	NOUN
admet-843	294	10	prediction	prediction	NOUN
admet-843	294	11	.	.	PUNCT
admet-843	295	1	journal	journal	NOUN
admet-843	295	2	of	of	ADP
admet-843	295	3	the	the	DET
admet-843	295	4	brazilian	brazilian	ADJ
admet-843	295	5	chemical	chemical	PROPN
admet-843	295	6	society	society	NOUN
admet-843	295	7	29	29	NUM
admet-843	295	8	(	(	PUNCT
admet-843	295	9	2018b	2018b	NUM
admet-843	295	10	)	)	PUNCT
admet-843	295	11	982	982	NUM
admet-843	295	12	-	-	PUNCT
admet-843	295	13	988	988	NUM
admet-843	295	14	.	.	PUNCT
admet-843	296	1	https://doi.org/10.21577/0103-5053.20180013	https://doi.org/10.21577/0103-5053.20180013	PROPN
admet-843	296	2	.	.	PUNCT
admet-843	297	1	[	[	X
admet-843	297	2	32	32	NUM
admet-843	297	3	]	]	PUNCT
admet-843	297	4	k.	k.	PROPN
admet-843	297	5	fernández	fernández	PROPN
admet-843	297	6	,	,	PUNCT
admet-843	297	7	m.	m.	NOUN
admet-843	297	8	roeckel	roeckel	PROPN
admet-843	297	9	,	,	PUNCT
admet-843	297	10	e.	e.	PROPN
admet-843	297	11	canales	canales	PROPN
admet-843	297	12	,	,	PUNCT
admet-843	297	13	j.	j.	PROPN
admet-843	297	14	dumont	dumont	PROPN
admet-843	297	15	.	.	PUNCT
admet-843	298	1	modeling	modeling	NOUN
admet-843	298	2	of	of	ADP
admet-843	298	3	the	the	DET
admet-843	298	4	nanoparticles	nanoparticle	NOUN
admet-843	298	5	absorption	absorption	NOUN
admet-843	298	6	under	under	ADP
admet-843	298	7	a	a	DET
admet-843	298	8	gastrointestinal	gastrointestinal	ADJ
admet-843	298	9	simulated	simulate	VERB
admet-843	298	10	ambient	ambient	ADJ
admet-843	298	11	condition	condition	NOUN
admet-843	298	12	.	.	PUNCT
admet-843	299	1	aaps	aap	NOUN
admet-843	299	2	pharmscitech	pharmscitech	VERB
admet-843	299	3	18	18	NUM
admet-843	299	4	(	(	PUNCT
admet-843	299	5	2017	2017	NUM
admet-843	299	6	)	)	PUNCT
admet-843	299	7	2691	2691	NUM
admet-843	299	8	-	-	SYM
admet-843	299	9	2701	2701	NUM
admet-843	299	10	.	.	PUNCT
admet-843	300	1	doi	doi	NOUN
admet-843	300	2	:	:	PUNCT
admet-843	300	3	https://doi.org/10.1208/s12249-017-0751-z	https://doi.org/10.1208/s12249-017-0751-z	NOUN
admet-843	300	4	.	.	PUNCT
admet-843	301	1	[	[	X
admet-843	301	2	33	33	NUM
admet-843	301	3	]	]	PUNCT
admet-843	301	4	w.	w.	PROPN
admet-843	301	5	li	li	PROPN
admet-843	301	6	,	,	PUNCT
admet-843	301	7	x.	x.	PROPN
admet-843	301	8	li	li	PROPN
admet-843	301	9	,	,	PUNCT
admet-843	301	10	,	,	PUNCT
admet-843	301	11	y.	y.	PROPN
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admet-843	301	13	,	,	PUNCT
admet-843	301	14	,	,	PUNCT
admet-843	301	15	y.	y.	PROPN
admet-843	301	16	zhou	zhou	PROPN
admet-843	301	17	,	,	PUNCT
admet-843	301	18	s.	s.	PROPN
admet-843	301	19	ma	ma	PROPN
admet-843	301	20	,	,	PUNCT
admet-843	301	21	y.	y.	PROPN
admet-843	301	22	zhao	zhao	PROPN
admet-843	301	23	,	,	PUNCT
admet-843	301	24	j.	j.	PROPN
admet-843	301	25	li	li	PROPN
admet-843	301	26	,	,	PUNCT
admet-843	301	27	y.	y.	PROPN
admet-843	301	28	liu	liu	PROPN
admet-843	301	29	,	,	PUNCT
admet-843	301	30	x.	x.	PROPN
admet-843	301	31	wang	wang	PROPN
admet-843	301	32	,	,	PUNCT
admet-843	301	33	d.	d.	PROPN
admet-843	301	34	yin	yin	PROPN
admet-843	301	35	.	.	PUNCT
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admet-843	302	2	mechanism	mechanism	NOUN
admet-843	302	3	of	of	ADP
admet-843	302	4	pglycoprotein	pglycoprotein	ADJ
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admet-843	302	6	efflux	efflux	NOUN
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admet-843	302	8	mpeg	mpeg	NOUN
admet-843	302	9	-	-	PUNCT
admet-843	302	10	pla	pla	NOUN
admet-843	302	11	and	and	CCONJ
admet-843	302	12	influence	influence	NOUN
admet-843	302	13	of	of	ADP
admet-843	302	14	pla	pla	PROPN
admet-843	302	15	chain	chain	NOUN
admet-843	302	16	length	length	NOUN
admet-843	302	17	on	on	ADP
admet-843	302	18	p	p	NOUN
admet-843	302	19	-	-	PUNCT
admet-843	302	20	glycoprotein	glycoprotein	NOUN
admet-843	302	21	http://dx.doi.org/10.5599/admet.843	http://dx.doi.org/10.5599/admet.843	NOUN
admet-843	302	22	https://doi.org/10.1021/ci300367a	https://doi.org/10.1021/ci300367a	NOUN
admet-843	302	23	https://doi.org/10.1093/bioinformatics/bty707	https://doi.org/10.1093/bioinformatics/bty707	NOUN
admet-843	302	24	https://doi.org/10.1021/acs.jcim.7b00194	https://doi.org/10.1021/acs.jcim.7b00194	INTJ
admet-843	302	25	https://doi.org/10.1021/acs.jcim.7b00194	https://doi.org/10.1021/acs.jcim.7b00194	INTJ
admet-843	302	26	https://doi.org/10.1021/acssuschemeng.7b04220	https://doi.org/10.1021/acssuschemeng.7b04220	VERB
admet-843	302	27	https://doi.org/10.1021/acssuschemeng.7b04220	https://doi.org/10.1021/acssuschemeng.7b04220	ADP
admet-843	302	28	https://doi.org/10.1021/ci400649p	https://doi.org/10.1021/ci400649p	X
admet-843	302	29	https://doi.org/10.1080/10629360802083871	https://doi.org/10.1080/10629360802083871	PROPN
admet-843	302	30	https://doi.org/10.1038/s41598-017-02365-0	https://doi.org/10.1038/s41598-017-02365-0	NUM
admet-843	302	31	https://doi.org/10.1007/s11095-018-2353-1	https://doi.org/10.1007/s11095-018-2353-1	NUM
admet-843	302	32	https://doi.org/10.1016/j.fct.2017.04.008	https://doi.org/10.1016/j.fct.2017.04.008	PROPN
admet-843	302	33	https://dx.doi.org/10.5599/admet.668	https://dx.doi.org/10.5599/admet.668	NOUN
admet-843	302	34	https://dx.doi.org/10.5599/admet.668	https://dx.doi.org/10.5599/admet.668	AUX
admet-843	303	1	https://doi.org/10.5599/admet.5.3.423	https://doi.org/10.5599/admet.5.3.423	NOUN
admet-843	303	2	https://doi.org/10.1002/minf.201500040	https://doi.org/10.1002/minf.201500040	NOUN
admet-843	303	3	https://doi.org/10.21577/0103-5053.20180013	https://doi.org/10.21577/0103-5053.20180013	PROPN
admet-843	303	4	https://doi.org/10.1208/s12249-017-0751-z	https://doi.org/10.1208/s12249-017-0751-z	PROPN
admet-843	303	5	d.	d.	PROPN
admet-843	303	6	dascălu	dascălu	INTJ
admet-843	303	7	et	et	PROPN
admet-843	303	8	al	al	PROPN
admet-843	303	9	.	.	PROPN
admet-843	303	10	admet	admet	PROPN
admet-843	303	11	&	&	CCONJ
admet-843	303	12	dmpk	dmpk	PROPN
admet-843	303	13	8(4	8(4	NOUN
admet-843	303	14	)	)	PUNCT
admet-843	303	15	(	(	PUNCT
admet-843	303	16	2020	2020	NUM
admet-843	303	17	)	)	PUNCT
admet-843	303	18	425	425	NUM
admet-843	303	19	-	-	SYM
admet-843	303	20	436	436	NUM
admet-843	303	21	436	436	NUM
admet-843	303	22	inhibition	inhibition	NOUN
admet-843	303	23	activity	activity	NOUN
admet-843	303	24	.	.	PUNCT
admet-843	304	1	molecular	molecular	ADJ
admet-843	304	2	pharmaceutics	pharmaceutic	NOUN
admet-843	304	3	11	11	NUM
admet-843	304	4	(	(	PUNCT
admet-843	304	5	2013	2013	NUM
admet-843	304	6	)	)	PUNCT
admet-843	304	7	71–80	71–80	NUM
admet-843	304	8	.	.	PUNCT
admet-843	305	1	doi	doi	NOUN
admet-843	305	2	:	:	PUNCT
admet-843	305	3	https://doi.org/10.1021/mp4004223	https://doi.org/10.1021/mp4004223	X
admet-843	305	4	.	.	PUNCT
admet-843	306	1	[	[	X
admet-843	306	2	34	34	NUM
admet-843	306	3	]	]	PUNCT
admet-843	306	4	m.	m.	NOUN
admet-843	306	5	mokhtar	mokhtar	PROPN
admet-843	306	6	,	,	PUNCT
admet-843	306	7	p.	p.	PROPN
admet-843	306	8	gosselin	gosselin	PROPN
admet-843	306	9	,	,	PUNCT
admet-843	306	10	f.	f.	PROPN
admet-843	306	11	lacasse	lacasse	PROPN
admet-843	306	12	,	,	PUNCT
admet-843	306	13	p.	p.	PROPN
admet-843	306	14	hildgen	hildgen	PROPN
admet-843	306	15	.	.	PUNCT
admet-843	307	1	design	design	NOUN
admet-843	307	2	of	of	ADP
admet-843	307	3	peg	peg	NOUN
admet-843	307	4	-	-	PUNCT
admet-843	307	5	grafted	graft	VERB
admet-843	307	6	-	-	PUNCT
admet-843	307	7	pla	pla	NOUN
admet-843	307	8	nanoparticles	nanoparticle	NOUN
admet-843	307	9	as	as	ADP
admet-843	307	10	oral	oral	ADJ
admet-843	307	11	permeability	permeability	NOUN
admet-843	307	12	enhancer	enhancer	NOUN
admet-843	307	13	for	for	ADP
admet-843	307	14	p	p	NOUN
admet-843	307	15	-	-	PUNCT
admet-843	307	16	gp	gp	NOUN
admet-843	307	17	substrate	substrate	NOUN
admet-843	307	18	drug	drug	NOUN
admet-843	307	19	model	model	NOUN
admet-843	307	20	famotidine	famotidine	PROPN
admet-843	307	21	.	.	PUNCT
admet-843	308	1	journal	journal	PROPN
admet-843	308	2	of	of	ADP
admet-843	308	3	microencapsulation	microencapsulation	NOUN
admet-843	308	4	34(1	34(1	NOUN
admet-843	308	5	)	)	PUNCT
admet-843	308	6	(	(	PUNCT
admet-843	308	7	2017	2017	NUM
admet-843	308	8	)	)	PUNCT
admet-843	308	9	91–103	91–103	NUM
admet-843	308	10	.	.	PUNCT
admet-843	308	11	doi	doi	PROPN
admet-843	308	12	:	:	PUNCT
admet-843	308	13	https://doi.org/10.1080/02652048.2017.1290155	https://doi.org/10.1080/02652048.2017.1290155	PROPN
admet-843	308	14	.	.	PUNCT
admet-843	309	1	[	[	X
admet-843	309	2	35	35	NUM
admet-843	309	3	]	]	X
admet-843	309	4	j.c	j.c	PROPN
admet-843	309	5	.	.	PROPN
admet-843	309	6	chatham	chatham	PROPN
admet-843	309	7	,	,	PUNCT
admet-843	309	8	j.r	j.r	PROPN
admet-843	309	9	.	.	PROPN
admet-843	309	10	forder	forder	NOUN
admet-843	309	11	.	.	PUNCT
admet-843	309	12	lactic	lactic	ADJ
admet-843	309	13	acid	acid	NOUN
admet-843	309	14	and	and	CCONJ
admet-843	309	15	protein	protein	NOUN
admet-843	309	16	interactions	interaction	NOUN
admet-843	309	17	:	:	PUNCT
admet-843	309	18	implications	implication	NOUN
admet-843	309	19	for	for	ADP
admet-843	309	20	the	the	DET
admet-843	309	21	nmr	nmr	NOUN
admet-843	309	22	visibility	visibility	NOUN
admet-843	309	23	of	of	ADP
admet-843	309	24	lactate	lactate	NOUN
admet-843	309	25	in	in	ADP
admet-843	309	26	biological	biological	ADJ
admet-843	309	27	systems	system	NOUN
admet-843	309	28	.	.	PUNCT
admet-843	310	1	biochim	biochim	PROPN
admet-843	310	2	biophys	biophy	NOUN
admet-843	310	3	acta	acta	PROPN
admet-843	310	4	1426	1426	NUM
admet-843	310	5	(	(	PUNCT
admet-843	310	6	1999	1999	NUM
admet-843	310	7	)	)	PUNCT
admet-843	310	8	177	177	NUM
admet-843	310	9	-	-	SYM
admet-843	310	10	184	184	NUM
admet-843	310	11	.	.	PUNCT
admet-843	311	1	doi	doi	NOUN
admet-843	311	2	:	:	PUNCT
admet-843	311	3	https://doi.org/10.1016/s0304-4165(98)00154-8	https://doi.org/10.1016/s0304-4165(98)00154-8	NOUN
admet-843	311	4	.	.	PUNCT
admet-843	312	1	[	[	X
admet-843	312	2	36	36	NUM
admet-843	312	3	]	]	X
admet-843	312	4	t.	t.	PROPN
admet-843	312	5	verrecchia	verrecchia	PROPN
admet-843	312	6	,	,	PUNCT
admet-843	312	7	p.	p.	NOUN
admet-843	312	8	huve	huve	NOUN
admet-843	312	9	,	,	PUNCT
admet-843	312	10	d.	d.	PROPN
admet-843	312	11	bazile	bazile	NOUN
admet-843	312	12	,	,	PUNCT
admet-843	312	13	m.	m.	NOUN
admet-843	312	14	veillard	veillard	PROPN
admet-843	312	15	,	,	PUNCT
admet-843	312	16	g.	g.	PROPN
admet-843	312	17	spenlehauer	spenlehauer	PROPN
admet-843	312	18	,	,	PUNCT
admet-843	312	19	p.	p.	PROPN
admet-843	312	20	couvreur	couvreur	PROPN
admet-843	312	21	.	.	PUNCT
admet-843	312	22	adsorption	adsorption	NOUN
admet-843	312	23	/	/	SYM
admet-843	312	24	desorption	desorption	NOUN
admet-843	312	25	of	of	ADP
admet-843	312	26	human	human	ADJ
admet-843	312	27	serum	serum	NOUN
admet-843	312	28	albumin	albumin	NOUN
admet-843	312	29	at	at	ADP
admet-843	312	30	the	the	DET
admet-843	312	31	surface	surface	NOUN
admet-843	312	32	of	of	ADP
admet-843	312	33	poly	poly	ADJ
admet-843	312	34	(	(	PUNCT
admet-843	312	35	1actic	1actic	ADJ
admet-843	312	36	acid	acid	NOUN
admet-843	312	37	)	)	PUNCT
admet-843	312	38	nanoparticles	nanoparticle	NOUN
admet-843	312	39	prepared	prepare	VERB
admet-843	312	40	by	by	ADP
admet-843	312	41	a	a	DET
admet-843	312	42	solvent	solvent	ADJ
admet-843	312	43	evaporation	evaporation	NOUN
admet-843	312	44	process	process	NOUN
admet-843	312	45	.	.	PUNCT
admet-843	313	1	journal	journal	PROPN
admet-843	313	2	of	of	ADP
admet-843	313	3	biomedical	biomedical	ADJ
admet-843	313	4	materials	material	NOUN
admet-843	313	5	research	research	NOUN
admet-843	313	6	27	27	NUM
admet-843	313	7	(	(	PUNCT
admet-843	313	8	1993	1993	NUM
admet-843	313	9	)	)	PUNCT
admet-843	313	10	1019	1019	NUM
admet-843	313	11	-	-	SYM
admet-843	313	12	1028	1028	NUM
admet-843	313	13	.	.	PUNCT
admet-843	314	1	https://doi.org/10.1002/jbm.820270807	https://doi.org/10.1002/jbm.820270807	NOUN
admet-843	314	2	.	.	PUNCT
admet-843	315	1	[	[	X
admet-843	315	2	37	37	NUM
admet-843	315	3	]	]	X
admet-843	315	4	wang	wang	PROPN
admet-843	315	5	hf	hf	PROPN
admet-843	315	6	,	,	PUNCT
admet-843	315	7	hu	hu	PROPN
admet-843	315	8	y	y	PROPN
admet-843	315	9	,	,	PUNCT
admet-843	315	10	sun	sun	PROPN
admet-843	315	11	wq	wq	PROPN
admet-843	315	12	,	,	PUNCT
admet-843	315	13	xie	xie	PROPN
admet-843	315	14	cs	cs	PROPN
admet-843	315	15	.	.	PROPN
admet-843	315	16	polylactic	polylactic	ADJ
admet-843	315	17	acid	acid	NOUN
admet-843	315	18	nanoparticles	nanoparticle	NOUN
admet-843	315	19	across	across	ADP
admet-843	315	20	the	the	DET
admet-843	315	21	brain	brain	NOUN
admet-843	315	22	-	-	PUNCT
admet-843	315	23	blood	blood	NOUN
admet-843	315	24	barrier	barrier	NOUN
admet-843	315	25	observed	observe	VERB
admet-843	315	26	with	with	ADP
admet-843	315	27	analytical	analytical	ADJ
admet-843	315	28	electron	electron	NOUN
admet-843	315	29	microscopy	microscopy	NOUN
admet-843	315	30	.	.	PUNCT
admet-843	316	1	chinese	chinese	ADJ
admet-843	316	2	journal	journal	PROPN
admet-843	316	3	of	of	ADP
admet-843	316	4	biotechnology	biotechnology	NOUN
admet-843	316	5	20(5	20(5	NOUN
admet-843	316	6	)	)	PUNCT
admet-843	316	7	(	(	PUNCT
admet-843	316	8	2004	2004	NUM
admet-843	316	9	)	)	PUNCT
admet-843	316	10	790794	790794	NUM
admet-843	316	11	.	.	PUNCT
admet-843	317	1	https://pubmed.ncbi.nlm.nih.gov/15974011/.	https://pubmed.ncbi.nlm.nih.gov/15974011/.	PROPN
admet-843	318	1	[	[	X
admet-843	318	2	38	38	NUM
admet-843	318	3	]	]	PUNCT
admet-843	318	4	a.	a.	NOUN
admet-843	318	5	daina	daina	PROPN
admet-843	318	6	,	,	PUNCT
admet-843	318	7	v.	v.	PROPN
admet-843	318	8	zoete	zoete	PROPN
admet-843	318	9	.	.	PUNCT
admet-843	319	1	a	a	DET
admet-843	319	2	boiled	boil	VERB
admet-843	319	3	-	-	PUNCT
admet-843	319	4	egg	egg	NOUN
admet-843	319	5	to	to	PART
admet-843	319	6	predict	predict	VERB
admet-843	319	7	gastrointestinal	gastrointestinal	ADJ
admet-843	319	8	absorption	absorption	NOUN
admet-843	319	9	and	and	CCONJ
admet-843	319	10	brain	brain	NOUN
admet-843	319	11	penetration	penetration	NOUN
admet-843	319	12	of	of	ADP
admet-843	319	13	small	small	ADJ
admet-843	319	14	molecules	molecule	NOUN
admet-843	319	15	.	.	PUNCT
admet-843	320	1	chemmedchem	chemmedchem	PROPN
admet-843	320	2	11	11	NUM
admet-843	320	3	(	(	PUNCT
admet-843	320	4	2016	2016	NUM
admet-843	320	5	)	)	PUNCT
admet-843	320	6	1117–1121	1117–1121	NUM
admet-843	320	7	.	.	PUNCT
admet-843	321	1	doi	doi	NOUN
admet-843	321	2	:	:	PUNCT
admet-843	321	3	https://doi.org/10.1002/cmdc.201600182	https://doi.org/10.1002/cmdc.201600182	NOUN
admet-843	321	4	.	.	PUNCT
admet-843	322	1	[	[	X
admet-843	322	2	39	39	NUM
admet-843	322	3	]	]	X
admet-843	322	4	n.f	n.f	PROPN
admet-843	322	5	.	.	PROPN
admet-843	322	6	smith	smith	PROPN
admet-843	322	7	,	,	PUNCT
admet-843	322	8	w.d	w.d	PROPN
admet-843	322	9	.	.	PROPN
admet-843	322	10	figg	figg	PROPN
admet-843	322	11	,	,	PUNCT
admet-843	322	12	a.	a.	NOUN
admet-843	322	13	sparreboom	sparreboom	NOUN
admet-843	322	14	.	.	PUNCT
admet-843	323	1	role	role	NOUN
admet-843	323	2	of	of	ADP
admet-843	323	3	the	the	DET
admet-843	323	4	liver	liver	NOUN
admet-843	323	5	-	-	PUNCT
admet-843	323	6	specific	specific	ADJ
admet-843	323	7	transporters	transporter	NOUN
admet-843	323	8	oatp1b1	oatp1b1	X
admet-843	323	9	and	and	CCONJ
admet-843	323	10	oatp1b3	oatp1b3	NOUN
admet-843	323	11	in	in	ADP
admet-843	323	12	governing	govern	VERB
admet-843	323	13	drug	drug	NOUN
admet-843	323	14	elimination	elimination	NOUN
admet-843	323	15	.	.	PUNCT
admet-843	324	1	expert	expert	ADJ
admet-843	324	2	opinion	opinion	NOUN
admet-843	324	3	on	on	ADP
admet-843	324	4	drug	drug	NOUN
admet-843	324	5	metabolism	metabolism	NOUN
admet-843	324	6	&	&	CCONJ
admet-843	324	7	toxicology	toxicology	NOUN
admet-843	324	8	1	1	NUM
admet-843	324	9	(	(	PUNCT
admet-843	324	10	2005	2005	NUM
admet-843	324	11	)	)	PUNCT
admet-843	324	12	429	429	NUM
admet-843	324	13	-	-	SYM
admet-843	324	14	445	445	NUM
admet-843	324	15	.	.	PUNCT
admet-843	325	1	https://doi.org/10.1517/17425255.1.3.429	https://doi.org/10.1517/17425255.1.3.429	NOUN
admet-843	325	2	.	.	PUNCT
admet-843	326	1	[	[	X
admet-843	326	2	40	40	NUM
admet-843	326	3	]	]	X
admet-843	326	4	s.a	s.a	PROPN
admet-843	326	5	.	.	PROPN
admet-843	326	6	roberts	roberts	PROPN
admet-843	326	7	,	,	PUNCT
admet-843	326	8	b.p	b.p	PROPN
admet-843	326	9	.	.	PROPN
admet-843	326	10	arthurs	arthurs	PROPN
admet-843	326	11	.	.	PUNCT
admet-843	327	1	severe	severe	ADJ
admet-843	327	2	visual	visual	ADJ
admet-843	327	3	loss	loss	NOUN
admet-843	327	4	and	and	CCONJ
admet-843	327	5	orbital	orbital	ADJ
admet-843	327	6	infarction	infarction	NOUN
admet-843	327	7	following	follow	VERB
admet-843	327	8	periorbital	periorbital	ADJ
admet-843	327	9	aesthetic	aesthetic	ADJ
admet-843	327	10	poly-(l)-lactic	poly-(l)-lactic	ADJ
admet-843	327	11	acid	acid	NOUN
admet-843	327	12	(	(	PUNCT
admet-843	327	13	plla	plla	NOUN
admet-843	327	14	)	)	PUNCT
admet-843	327	15	injection	injection	NOUN
admet-843	327	16	.	.	PUNCT
admet-843	328	1	ophthalmic	ophthalmic	ADJ
admet-843	328	2	plastic	plastic	NOUN
admet-843	328	3	and	and	CCONJ
admet-843	328	4	reconstructive	reconstructive	ADJ
admet-843	328	5	surgery	surgery	NOUN
admet-843	328	6	28	28	NUM
admet-843	328	7	(	(	PUNCT
admet-843	328	8	2012	2012	NUM
admet-843	328	9	)	)	PUNCT
admet-843	328	10	68	68	NUM
admet-843	328	11	-	-	SYM
admet-843	328	12	70	70	NUM
admet-843	328	13	.	.	PUNCT
admet-843	329	1	doi	doi	NOUN
admet-843	329	2	:	:	PUNCT
admet-843	329	3	https://doi.org/10.1097/iop.0b013e3182288e4d	https://doi.org/10.1097/iop.0b013e3182288e4d	X
admet-843	329	4	.	.	PUNCT
admet-843	330	1	[	[	X
admet-843	330	2	41	41	NUM
admet-843	330	3	]	]	X
admet-843	330	4	r.a	r.a	PROPN
admet-843	330	5	.	.	PROPN
admet-843	330	6	abd	abd	PROPN
admet-843	330	7	alsaheb	alsaheb	PROPN
admet-843	330	8	,	,	PUNCT
admet-843	330	9	a.	a.	NOUN
admet-843	330	10	aladdin	aladdin	NOUN
admet-843	330	11	,	,	PUNCT
admet-843	330	12	n.z	n.z	PROPN
admet-843	330	13	.	.	PROPN
admet-843	330	14	othman	othman	PROPN
admet-843	330	15	,	,	PUNCT
admet-843	330	16	r.a	r.a	PROPN
admet-843	330	17	.	.	PROPN
admet-843	330	18	malek	malek	PROPN
admet-843	330	19	,	,	PUNCT
admet-843	330	20	o.m	o.m	PROPN
admet-843	330	21	.	.	PUNCT
admet-843	330	22	leng	leng	PROPN
admet-843	330	23	,	,	PUNCT
admet-843	330	24	r.	r.	PROPN
admet-843	330	25	aziz	aziz	PROPN
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