id	sid	tid	token	lemma	pos
admet-910	1	1	strategies	strategy	NOUN
admet-910	1	2	of	of	ADP
admet-910	1	3	solubility	solubility	NOUN
admet-910	1	4	enhancement	enhancement	NOUN
admet-910	1	5	and	and	CCONJ
admet-910	1	6	perspectives	perspective	NOUN
admet-910	1	7	in	in	ADP
admet-910	1	8	solubility	solubility	NOUN
admet-910	1	9	measurements	measurement	NOUN
admet-910	1	10	of	of	ADP
admet-910	1	11	pharmaceutical	pharmaceutical	NOUN
admet-910	1	12	compounds	compound	NOUN
admet-910	1	13	doi	doi	NOUN
admet-910	1	14	:	:	PUNCT
admet-910	1	15	https://doi.org/10.5599/admet.910	https://doi.org/10.5599/admet.910	PROPN
admet-910	1	16	176	176	NUM
admet-910	1	17	admet	admet	X
admet-910	1	18	&	&	CCONJ
admet-910	1	19	dmpk	dmpk	PROPN
admet-910	1	20	8(3	8(3	NUM
admet-910	1	21	)	)	PUNCT
admet-910	1	22	(	(	PUNCT
admet-910	1	23	2020	2020	NUM
admet-910	1	24	)	)	PUNCT
admet-910	1	25	176	176	NUM
admet-910	1	26	-	-	SYM
admet-910	1	27	179	179	NUM
admet-910	1	28	;	;	PUNCT
admet-910	1	29	doi	doi	NOUN
admet-910	1	30	:	:	PUNCT
admet-910	1	31	http://dx.doi.org/10.5599/admet.910	http://dx.doi.org/10.5599/admet.910	NOUN
admet-910	1	32	open	open	ADJ
admet-910	1	33	access	access	NOUN
admet-910	1	34	:	:	PUNCT
admet-910	1	35	issn	issn	PROPN
admet-910	1	36	:	:	PUNCT
admet-910	1	37	1848	1848	NUM
admet-910	1	38	-	-	SYM
admet-910	1	39	7718	7718	NUM
admet-910	1	40	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-910	1	41	editorial	editorial	ADJ
admet-910	1	42	strategies	strategy	NOUN
admet-910	1	43	of	of	ADP
admet-910	1	44	solubility	solubility	NOUN
admet-910	1	45	enhancement	enhancement	NOUN
admet-910	1	46	and	and	CCONJ
admet-910	1	47	perspectives	perspective	NOUN
admet-910	1	48	in	in	ADP
admet-910	1	49	solubility	solubility	NOUN
admet-910	1	50	measurements	measurement	NOUN
admet-910	1	51	of	of	ADP
admet-910	1	52	pharmaceutical	pharmaceutical	NOUN
admet-910	1	53	compounds	compound	VERB
admet-910	1	54	christel	christel	PROPN
admet-910	1	55	a.s	a.s	PROPN
admet-910	1	56	.	.	PROPN
admet-910	1	57	bergström1,2	bergström1,2	PROPN
admet-910	1	58	*	*	PROPN
admet-910	1	59	and	and	CCONJ
admet-910	1	60	antonio	antonio	PROPN
admet-910	1	61	llinas3	llinas3	PROPN
admet-910	1	62	*	*	SYM
admet-910	1	63	1	1	NUM
admet-910	1	64	department	department	NOUN
admet-910	1	65	of	of	ADP
admet-910	1	66	pharmacy	pharmacy	NOUN
admet-910	1	67	,	,	PUNCT
admet-910	1	68	uppsala	uppsala	PROPN
admet-910	1	69	university	university	PROPN
admet-910	1	70	,	,	PUNCT
admet-910	1	71	uppsala	uppsala	PROPN
admet-910	1	72	biomedical	biomedical	PROPN
admet-910	1	73	center	center	PROPN
admet-910	1	74	,	,	PUNCT
admet-910	1	75	p.o	p.o	PROPN
admet-910	1	76	.	.	PROPN
admet-910	1	77	box	box	PROPN
admet-910	1	78	580,se-751	580,se-751	PROPN
admet-910	1	79	23	23	NUM
admet-910	1	80	uppsala	uppsala	PROPN
admet-910	1	81	,	,	PUNCT
admet-910	1	82	sweden	sweden	PROPN
admet-910	1	83	2	2	NUM
admet-910	1	84	the	the	DET
admet-910	1	85	swedish	swedish	ADJ
admet-910	1	86	drug	drug	NOUN
admet-910	1	87	delivery	delivery	NOUN
admet-910	1	88	center	center	NOUN
admet-910	1	89	,	,	PUNCT
admet-910	1	90	department	department	NOUN
admet-910	1	91	of	of	ADP
admet-910	1	92	pharmacy	pharmacy	NOUN
admet-910	1	93	,	,	PUNCT
admet-910	1	94	uppsala	uppsala	PROPN
admet-910	1	95	university	university	PROPN
admet-910	1	96	,	,	PUNCT
admet-910	1	97	uppsala	uppsala	PROPN
admet-910	1	98	biomedical	biomedical	PROPN
admet-910	1	99	center	center	PROPN
admet-910	1	100	,	,	PUNCT
admet-910	1	101	p.o	p.o	PROPN
admet-910	1	102	.	.	PROPN
admet-910	1	103	box	box	PROPN
admet-910	1	104	580	580	NUM
admet-910	1	105	,	,	PUNCT
admet-910	1	106	se-751	se-751	PROPN
admet-910	1	107	23	23	NUM
admet-910	1	108	uppsala	uppsala	PROPN
admet-910	1	109	,	,	PUNCT
admet-910	1	110	sweden	sweden	PROPN
admet-910	1	111	3	3	NUM
admet-910	1	112	respiratory	respiratory	NOUN
admet-910	1	113	,	,	PUNCT
admet-910	1	114	inflammation	inflammation	NOUN
admet-910	1	115	and	and	CCONJ
admet-910	1	116	autoimmunity	autoimmunity	NOUN
admet-910	1	117	imed	imed	PROPN
admet-910	1	118	biotech	biotech	PROPN
admet-910	1	119	unit	unit	NOUN
admet-910	1	120	,	,	PUNCT
admet-910	1	121	astrazeneca	astrazeneca	PROPN
admet-910	1	122	,	,	PUNCT
admet-910	1	123	gothenburg	gothenburg	PROPN
admet-910	1	124	,	,	PUNCT
admet-910	1	125	sweden	sweden	PROPN
admet-910	1	126	*	*	PUNCT
admet-910	1	127	corresponding	correspond	VERB
admet-910	1	128	authors	author	NOUN
admet-910	1	129	emails	email	NOUN
admet-910	1	130	:	:	PUNCT
admet-910	1	131	christel.bergstrom@farmaci.uu.se	christel.bergstrom@farmaci.uu.se	NUM
admet-910	1	132	;	;	PUNCT
admet-910	1	133	antonio.llinas@astrazeneca.com	antonio.llinas@astrazeneca.com	X
admet-910	1	134	.	.	PUNCT
admet-910	2	1	received	receive	VERB
admet-910	2	2	:	:	PUNCT
admet-910	2	3	september	september	PROPN
admet-910	2	4	19	19	NUM
admet-910	2	5	,	,	PUNCT
admet-910	2	6	2020	2020	NUM
admet-910	2	7	;	;	PUNCT
admet-910	2	8	revised	revise	VERB
admet-910	2	9	:	:	PUNCT
admet-910	2	10	september	september	PROPN
admet-910	2	11	25	25	NUM
admet-910	2	12	,	,	PUNCT
admet-910	2	13	2020	2020	NUM
admet-910	2	14	;	;	PUNCT
admet-910	2	15	published	publish	VERB
admet-910	2	16	:	:	PUNCT
admet-910	2	17	september	september	PROPN
admet-910	2	18	27	27	NUM
admet-910	2	19	,	,	PUNCT
admet-910	2	20	2020	2020	NUM
admet-910	2	21	the	the	DET
admet-910	2	22	genesis	genesis	NOUN
admet-910	2	23	of	of	ADP
admet-910	2	24	this	this	DET
admet-910	2	25	theme	theme	NOUN
admet-910	2	26	issue	issue	NOUN
admet-910	2	27	was	be	AUX
admet-910	2	28	a	a	DET
admet-910	2	29	conversation	conversation	NOUN
admet-910	2	30	we	we	PRON
admet-910	2	31	had	have	VERB
admet-910	2	32	during	during	ADP
admet-910	2	33	the	the	DET
admet-910	2	34	iapc-8	iapc-8	NUM
admet-910	2	35	meeting	meeting	NOUN
admet-910	2	36	in	in	ADP
admet-910	2	37	split	split	NOUN
admet-910	2	38	,	,	PUNCT
admet-910	2	39	croatia	croatia	PROPN
admet-910	2	40	in	in	ADP
admet-910	2	41	september	september	PROPN
admet-910	2	42	2019	2019	NUM
admet-910	2	43	.	.	PUNCT
admet-910	3	1	in	in	ADP
admet-910	3	2	it	it	PRON
admet-910	3	3	,	,	PUNCT
admet-910	3	4	we	we	PRON
admet-910	3	5	started	start	VERB
admet-910	3	6	the	the	DET
admet-910	3	7	interesting	interesting	ADJ
admet-910	3	8	and	and	CCONJ
admet-910	3	9	important	important	ADJ
admet-910	3	10	discussions	discussion	NOUN
admet-910	3	11	surrounding	surround	VERB
admet-910	3	12	the	the	DET
admet-910	3	13	special	special	ADJ
admet-910	3	14	session	session	NOUN
admet-910	3	15	dedicated	dedicate	VERB
admet-910	3	16	to	to	ADP
admet-910	3	17	‘	'	PUNCT
admet-910	3	18	state	state	NOUN
admet-910	3	19	-	-	PUNCT
admet-910	3	20	of	of	ADP
admet-910	3	21	-	-	PUNCT
admet-910	3	22	the	the	DET
admet-910	3	23	-	-	PUNCT
admet-910	3	24	art	art	NOUN
admet-910	3	25	solubility	solubility	NOUN
admet-910	3	26	in	in	ADP
admet-910	3	27	drug	drug	NOUN
admet-910	3	28	development	development	NOUN
admet-910	3	29	’	'	PUNCT
admet-910	3	30	.	.	PUNCT
admet-910	4	1	the	the	DET
admet-910	4	2	session	session	NOUN
admet-910	4	3	was	be	AUX
admet-910	4	4	introduced	introduce	VERB
admet-910	4	5	in	in	ADP
admet-910	4	6	the	the	DET
admet-910	4	7	preliminary	preliminary	ADJ
admet-910	4	8	mini	mini	ADJ
admet-910	4	9	-	-	ADJ
admet-910	4	10	review	review	NOUN
admet-910	4	11	paper	paper	NOUN
admet-910	4	12	intended	intend	VERB
admet-910	4	13	to	to	PART
admet-910	4	14	serve	serve	VERB
admet-910	4	15	as	as	ADP
admet-910	4	16	prologue	prologue	NOUN
admet-910	4	17	or	or	CCONJ
admet-910	4	18	accompaniment	accompaniment	NOUN
admet-910	4	19	to	to	ADP
admet-910	4	20	an	an	DET
admet-910	4	21	upcoming	upcoming	ADJ
admet-910	4	22	session	session	NOUN
admet-910	4	23	on	on	ADP
admet-910	4	24	solubility	solubility	NOUN
admet-910	4	25	at	at	ADP
admet-910	4	26	the	the	DET
admet-910	4	27	iapc-8	iapc-8	NUM
admet-910	4	28	meeting	meeting	NOUN
admet-910	4	29	in	in	ADP
admet-910	4	30	split	split	NOUN
admet-910	4	31	,	,	PUNCT
admet-910	4	32	croatia	croatia	PROPN
admet-910	4	33	,	,	PUNCT
admet-910	4	34	9	9	NUM
admet-910	4	35	-	-	SYM
admet-910	4	36	11	11	NUM
admet-910	4	37	september	september	NOUN
admet-910	4	38	2019	2019	NUM
admet-910	5	1	[	[	X
admet-910	5	2	1	1	NUM
admet-910	5	3	]	]	PUNCT
admet-910	5	4	.	.	PUNCT
admet-910	6	1	the	the	DET
admet-910	6	2	session	session	NOUN
admet-910	6	3	had	have	AUX
admet-910	6	4	received	receive	VERB
admet-910	6	5	a	a	DET
admet-910	6	6	high	high	ADJ
admet-910	6	7	number	number	NOUN
admet-910	6	8	of	of	ADP
admet-910	6	9	abstracts	abstract	NOUN
admet-910	6	10	and	and	CCONJ
admet-910	6	11	hence	hence	ADV
admet-910	6	12	,	,	PUNCT
admet-910	6	13	was	be	AUX
admet-910	6	14	extended	extend	VERB
admet-910	6	15	from	from	ADP
admet-910	6	16	a	a	DET
admet-910	6	17	half	half	ADJ
admet-910	6	18	-	-	PUNCT
admet-910	6	19	day	day	NOUN
admet-910	6	20	session	session	NOUN
admet-910	6	21	to	to	ADP
admet-910	6	22	a	a	DET
admet-910	6	23	session	session	NOUN
admet-910	6	24	spanning	span	VERB
admet-910	6	25	over	over	ADP
admet-910	6	26	two	two	NUM
admet-910	6	27	days	day	NOUN
admet-910	6	28	with	with	ADP
admet-910	6	29	many	many	ADJ
admet-910	6	30	engaged	engaged	ADJ
admet-910	6	31	speakers	speaker	NOUN
admet-910	6	32	on	on	ADP
admet-910	6	33	topics	topic	NOUN
admet-910	6	34	around	around	ADP
admet-910	6	35	solubility	solubility	NOUN
admet-910	6	36	,	,	PUNCT
admet-910	6	37	dissolution	dissolution	NOUN
admet-910	6	38	and	and	CCONJ
admet-910	6	39	enabling	enable	VERB
admet-910	6	40	formulation	formulation	NOUN
admet-910	6	41	strategies	strategy	NOUN
admet-910	6	42	.	.	PUNCT
admet-910	7	1	in	in	ADP
admet-910	7	2	response	response	NOUN
admet-910	7	3	to	to	ADP
admet-910	7	4	this	this	DET
admet-910	7	5	successful	successful	ADJ
admet-910	7	6	session	session	NOUN
admet-910	7	7	,	,	PUNCT
admet-910	7	8	professor	professor	NOUN
admet-910	7	9	mandic	mandic	ADJ
admet-910	7	10	and	and	CCONJ
admet-910	7	11	professor	professor	NOUN
admet-910	7	12	tam	tam	X
admet-910	7	13	in	in	ADP
admet-910	7	14	their	their	PRON
admet-910	7	15	role	role	NOUN
admet-910	7	16	as	as	SCONJ
admet-910	7	17	editors	editor	NOUN
admet-910	7	18	suggested	suggest	VERB
admet-910	7	19	us	we	PRON
admet-910	7	20	to	to	PART
admet-910	7	21	take	take	VERB
admet-910	7	22	lead	lead	NOUN
admet-910	7	23	for	for	ADP
admet-910	7	24	a	a	DET
admet-910	7	25	special	special	ADJ
admet-910	7	26	issue	issue	NOUN
admet-910	7	27	dedicated	dedicate	VERB
admet-910	7	28	to	to	ADP
admet-910	7	29	these	these	DET
admet-910	7	30	topics	topic	NOUN
admet-910	7	31	as	as	SCONJ
admet-910	7	32	they	they	PRON
admet-910	7	33	had	have	AUX
admet-910	7	34	listened	listen	VERB
admet-910	7	35	in	in	ADP
admet-910	7	36	to	to	ADP
admet-910	7	37	the	the	DET
admet-910	7	38	scientific	scientific	ADJ
admet-910	7	39	discussions	discussion	NOUN
admet-910	7	40	.	.	PUNCT
admet-910	8	1	we	we	PRON
admet-910	8	2	were	be	AUX
admet-910	8	3	both	both	PRON
admet-910	8	4	delighted	delighted	ADJ
admet-910	8	5	to	to	PART
admet-910	8	6	take	take	VERB
admet-910	8	7	on	on	ADP
admet-910	8	8	the	the	DET
admet-910	8	9	role	role	NOUN
admet-910	8	10	as	as	ADP
admet-910	8	11	guest	guest	NOUN
admet-910	8	12	editors	editor	NOUN
admet-910	8	13	.	.	PUNCT
admet-910	9	1	we	we	PRON
admet-910	9	2	have	have	AUX
admet-910	9	3	been	be	AUX
admet-910	9	4	overwhelmed	overwhelm	VERB
admet-910	9	5	by	by	ADP
admet-910	9	6	the	the	DET
admet-910	9	7	response	response	NOUN
admet-910	9	8	and	and	CCONJ
admet-910	9	9	number	number	NOUN
admet-910	9	10	of	of	ADP
admet-910	9	11	high	high	ADJ
admet-910	9	12	quality	quality	NOUN
admet-910	9	13	articles	article	NOUN
admet-910	9	14	submitted	submit	VERB
admet-910	9	15	for	for	ADP
admet-910	9	16	this	this	DET
admet-910	9	17	special	special	ADJ
admet-910	9	18	issue	issue	NOUN
admet-910	9	19	.	.	PUNCT
admet-910	10	1	indeed	indeed	ADV
admet-910	10	2	,	,	PUNCT
admet-910	10	3	it	it	PRON
admet-910	10	4	was	be	AUX
admet-910	10	5	during	during	ADP
admet-910	10	6	the	the	DET
admet-910	10	7	course	course	NOUN
admet-910	10	8	of	of	ADP
admet-910	10	9	this	this	DET
admet-910	10	10	work	work	NOUN
admet-910	10	11	decided	decide	VERB
admet-910	10	12	to	to	PART
admet-910	10	13	split	split	VERB
admet-910	10	14	the	the	DET
admet-910	10	15	special	special	ADJ
admet-910	10	16	issue	issue	NOUN
admet-910	10	17	into	into	ADP
admet-910	10	18	two	two	NUM
admet-910	10	19	consecutive	consecutive	ADJ
admet-910	10	20	issues	issue	NOUN
admet-910	10	21	due	due	ADP
admet-910	10	22	to	to	ADP
admet-910	10	23	the	the	DET
admet-910	10	24	large	large	ADJ
admet-910	10	25	number	number	NOUN
admet-910	10	26	of	of	ADP
admet-910	10	27	papers	paper	NOUN
admet-910	10	28	being	be	AUX
admet-910	10	29	accepted	accept	VERB
admet-910	10	30	.	.	PUNCT
admet-910	11	1	with	with	ADP
admet-910	11	2	this	this	DET
admet-910	11	3	short	short	ADJ
admet-910	11	4	editorial	editorial	NOUN
admet-910	11	5	,	,	PUNCT
admet-910	11	6	we	we	PRON
admet-910	11	7	thank	thank	VERB
admet-910	11	8	all	all	DET
admet-910	11	9	authors	author	NOUN
admet-910	11	10	for	for	ADP
admet-910	11	11	their	their	PRON
admet-910	11	12	excellent	excellent	ADJ
admet-910	11	13	contribution	contribution	NOUN
admet-910	11	14	to	to	ADP
admet-910	11	15	this	this	DET
admet-910	11	16	special	special	ADJ
admet-910	11	17	issue	issue	NOUN
admet-910	11	18	on	on	ADP
admet-910	11	19	solubility	solubility	NOUN
admet-910	11	20	enhancement	enhancement	NOUN
admet-910	11	21	and	and	CCONJ
admet-910	11	22	measurements	measurement	NOUN
admet-910	11	23	.	.	PUNCT
admet-910	12	1	in	in	ADP
admet-910	12	2	the	the	DET
admet-910	12	3	first	first	ADJ
admet-910	12	4	issue	issue	NOUN
admet-910	12	5	of	of	ADP
admet-910	12	6	admet&dmpk	admet&dmpk	NOUN
admet-910	12	7	focus	focus	NOUN
admet-910	12	8	is	be	AUX
admet-910	12	9	set	set	VERB
admet-910	12	10	on	on	ADP
admet-910	12	11	computational	computational	ADJ
admet-910	12	12	tools	tool	NOUN
admet-910	12	13	and	and	CCONJ
admet-910	12	14	mathematical	mathematical	ADJ
admet-910	12	15	modelling	modelling	NOUN
admet-910	12	16	useful	useful	ADJ
admet-910	12	17	to	to	PART
admet-910	12	18	understand	understand	VERB
admet-910	12	19	solubility	solubility	NOUN
admet-910	12	20	and	and	CCONJ
admet-910	12	21	dissolution	dissolution	NOUN
admet-910	12	22	,	,	PUNCT
admet-910	12	23	with	with	ADP
admet-910	12	24	avdeef	avdeef	NOUN
admet-910	12	25	and	and	CCONJ
admet-910	12	26	kansy	kansy	VERB
admet-910	13	1	[	[	X
admet-910	13	2	2	2	NUM
admet-910	13	3	]	]	PUNCT
admet-910	13	4	as	as	ADV
admet-910	13	5	well	well	ADV
admet-910	13	6	as	as	ADP
admet-910	13	7	caron	caron	PROPN
admet-910	13	8	and	and	CCONJ
admet-910	13	9	colleagues	colleague	NOUN
admet-910	13	10	[	[	X
admet-910	13	11	3	3	X
admet-910	13	12	]	]	PUNCT
admet-910	13	13	focusing	focus	VERB
admet-910	13	14	their	their	PRON
admet-910	13	15	work	work	NOUN
admet-910	13	16	on	on	ADP
admet-910	13	17	compounds	compound	NOUN
admet-910	13	18	in	in	ADP
admet-910	13	19	the	the	DET
admet-910	13	20	beyond	beyond	ADP
admet-910	13	21	rule	rule	NOUN
admet-910	13	22	-	-	PUNCT
admet-910	13	23	of-5	of-5	PUNCT
admet-910	13	24	(	(	PUNCT
admet-910	13	25	bro5	bro5	NOUN
admet-910	13	26	)	)	PUNCT
admet-910	13	27	chemical	chemical	NOUN
admet-910	13	28	space	space	NOUN
admet-910	13	29	.	.	PUNCT
admet-910	14	1	avdeef	avdeef	PROPN
admet-910	14	2	and	and	CCONJ
admet-910	14	3	kansy	kansy	PROPN
admet-910	14	4	explored	explore	VERB
admet-910	14	5	to	to	ADP
admet-910	14	6	what	what	DET
admet-910	14	7	extent	extent	NOUN
admet-910	14	8	computational	computational	ADJ
admet-910	14	9	models	model	NOUN
admet-910	14	10	established	establish	VERB
admet-910	14	11	on	on	ADP
admet-910	14	12	training	training	NOUN
admet-910	14	13	sets	set	NOUN
admet-910	14	14	from	from	ADP
admet-910	14	15	the	the	DET
admet-910	14	16	small	small	ADJ
admet-910	14	17	molecular	molecular	ADJ
admet-910	14	18	chemical	chemical	NOUN
admet-910	14	19	space	space	NOUN
admet-910	14	20	were	be	AUX
admet-910	14	21	applicable	applicable	ADJ
admet-910	14	22	to	to	ADP
admet-910	14	23	the	the	DET
admet-910	14	24	bro5	bro5	NOUN
admet-910	14	25	chemical	chemical	NOUN
admet-910	14	26	space	space	NOUN
admet-910	14	27	.	.	PUNCT
admet-910	15	1	they	they	PRON
admet-910	15	2	concluded	conclude	VERB
admet-910	15	3	that	that	SCONJ
admet-910	15	4	random	random	ADJ
admet-910	15	5	forest	forest	NOUN
admet-910	15	6	(	(	PUNCT
admet-910	15	7	rf	rf	NOUN
admet-910	15	8	)	)	PUNCT
admet-910	15	9	regression	regression	NOUN
admet-910	15	10	methods	method	NOUN
admet-910	15	11	predicted	predict	VERB
admet-910	15	12	the	the	DET
admet-910	15	13	solubility	solubility	NOUN
admet-910	15	14	slightly	slightly	ADV
admet-910	15	15	better	well	ADV
admet-910	15	16	for	for	ADP
admet-910	15	17	these	these	DET
admet-910	15	18	compounds	compound	NOUN
admet-910	15	19	than	than	ADP
admet-910	15	20	the	the	DET
admet-910	15	21	general	general	ADJ
admet-910	15	22	solubility	solubility	NOUN
admet-910	15	23	equation	equation	NOUN
admet-910	15	24	(	(	PUNCT
admet-910	15	25	gse	gse	PROPN
admet-910	15	26	)	)	PUNCT
admet-910	15	27	and	and	CCONJ
admet-910	15	28	the	the	DET
admet-910	15	29	abraham	abraham	PROPN
admet-910	15	30	solvation	solvation	NOUN
admet-910	15	31	equation	equation	NOUN
admet-910	15	32	(	(	PUNCT
admet-910	15	33	absolv	absolv	PROPN
admet-910	15	34	)	)	PUNCT
admet-910	15	35	.	.	PUNCT
admet-910	16	1	however	however	ADV
admet-910	16	2	,	,	PUNCT
admet-910	16	3	the	the	DET
admet-910	16	4	gse	gse	NOUN
admet-910	16	5	performed	perform	VERB
admet-910	16	6	better	well	ADV
admet-910	16	7	(	(	PUNCT
admet-910	16	8	for	for	SCONJ
admet-910	16	9	the	the	DET
admet-910	16	10	dataset	dataset	NOUN
admet-910	16	11	explored	explore	VERB
admet-910	16	12	)	)	PUNCT
admet-910	16	13	when	when	SCONJ
admet-910	16	14	the	the	DET
admet-910	16	15	log	log	NOUN
admet-910	16	16	p	p	NOUN
admet-910	16	17	coefficient	coefficient	NOUN
admet-910	16	18	was	be	AUX
admet-910	16	19	changed	change	VERB
admet-910	16	20	from	from	ADP
admet-910	16	21	-1	-1	ADJ
admet-910	16	22	to	to	ADP
admet-910	16	23	-0.4	-0.4	NUM
admet-910	16	24	,	,	PUNCT
admet-910	16	25	providing	provide	VERB
admet-910	16	26	less	less	ADJ
admet-910	16	27	weight	weight	NOUN
admet-910	16	28	to	to	ADP
admet-910	16	29	lipophilicity	lipophilicity	NOUN
admet-910	16	30	in	in	ADP
admet-910	16	31	the	the	DET
admet-910	16	32	predictions	prediction	NOUN
admet-910	16	33	.	.	PUNCT
admet-910	17	1	they	they	PRON
admet-910	17	2	also	also	ADV
admet-910	17	3	concluded	conclude	VERB
admet-910	17	4	that	that	SCONJ
admet-910	17	5	the	the	DET
admet-910	17	6	increased	increase	VERB
admet-910	17	7	flexibility	flexibility	NOUN
admet-910	17	8	of	of	ADP
admet-910	17	9	the	the	DET
admet-910	17	10	larger	large	ADJ
admet-910	17	11	molecules	molecule	NOUN
admet-910	17	12	in	in	ADP
admet-910	17	13	the	the	DET
admet-910	17	14	bro5	bro5	NOUN
admet-910	17	15	space	space	NOUN
admet-910	17	16	is	be	AUX
admet-910	17	17	one	one	NUM
admet-910	17	18	of	of	ADP
admet-910	17	19	the	the	DET
admet-910	17	20	underlying	underlie	VERB
admet-910	17	21	reasons	reason	NOUN
admet-910	17	22	for	for	ADP
admet-910	17	23	less	less	ADV
admet-910	17	24	accurate	accurate	ADJ
admet-910	17	25	predictions	prediction	NOUN
admet-910	17	26	of	of	ADP
admet-910	17	27	traditionally	traditionally	ADV
admet-910	17	28	developed	develop	VERB
admet-910	17	29	models	model	NOUN
admet-910	17	30	.	.	PUNCT
admet-910	18	1	the	the	DET
admet-910	18	2	latter	latter	ADJ
admet-910	18	3	is	be	AUX
admet-910	18	4	also	also	ADV
admet-910	18	5	the	the	DET
admet-910	18	6	conclusion	conclusion	NOUN
admet-910	18	7	from	from	ADP
admet-910	18	8	the	the	DET
admet-910	18	9	study	study	NOUN
admet-910	18	10	by	by	ADP
admet-910	18	11	caron	caron	PROPN
admet-910	18	12	and	and	CCONJ
admet-910	18	13	coworkers	coworker	NOUN
admet-910	18	14	[	[	X
admet-910	18	15	3	3	NUM
admet-910	18	16	]	]	PUNCT
admet-910	18	17	.	.	PUNCT
admet-910	19	1	they	they	PRON
admet-910	19	2	emphasise	emphasise	VERB
admet-910	19	3	the	the	DET
admet-910	19	4	https://doi.org/10.5599/admet.910	https://doi.org/10.5599/admet.910	NOUN
admet-910	19	5	http://dx.doi.org/10.5599/admet.910	http://dx.doi.org/10.5599/admet.910	NOUN
admet-910	19	6	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-910	19	7	mailto:christel.bergstrom@farmaci.uu.se	mailto:christel.bergstrom@farmaci.uu.se	NOUN
admet-910	19	8	mailto:antonio.llinas@astrazeneca.com	mailto:antonio.llinas@astrazeneca.com	X
admet-910	19	9	admet	admet	PROPN
admet-910	19	10	&	&	CCONJ
admet-910	19	11	dmpk	dmpk	PROPN
admet-910	19	12	8(3	8(3	NUM
admet-910	19	13	)	)	PUNCT
admet-910	19	14	(	(	PUNCT
admet-910	19	15	2020	2020	NUM
admet-910	19	16	)	)	PUNCT
admet-910	19	17	176	176	NUM
admet-910	19	18	-	-	SYM
admet-910	19	19	179	179	NUM
admet-910	19	20	editorial	editorial	NOUN
admet-910	19	21	,	,	PUNCT
admet-910	19	22	solubility	solubility	NOUN
admet-910	19	23	issue	issue	NOUN
admet-910	19	24	doi	doi	PROPN
admet-910	19	25	:	:	PUNCT
admet-910	19	26	https://doi.org/10.5599/admet.910	https://doi.org/10.5599/admet.910	NOUN
admet-910	19	27	177	177	NUM
admet-910	19	28	role	role	NOUN
admet-910	19	29	of	of	ADP
admet-910	19	30	flexibility	flexibility	NOUN
admet-910	19	31	and	and	CCONJ
admet-910	19	32	its	its	PRON
admet-910	19	33	importance	importance	NOUN
admet-910	19	34	for	for	ADP
admet-910	19	35	chameleonic	chameleonic	ADJ
admet-910	19	36	behaviour	behaviour	NOUN
admet-910	19	37	,	,	PUNCT
admet-910	19	38	i.e.	i.e.	X
admet-910	19	39	the	the	DET
admet-910	19	40	ability	ability	NOUN
admet-910	19	41	of	of	ADP
admet-910	19	42	the	the	DET
admet-910	19	43	molecule	molecule	NOUN
admet-910	19	44	to	to	PART
admet-910	19	45	adopt	adopt	VERB
admet-910	19	46	to	to	ADP
admet-910	19	47	the	the	DET
admet-910	19	48	environment	environment	NOUN
admet-910	19	49	it	it	PRON
admet-910	19	50	is	be	AUX
admet-910	19	51	exposed	expose	VERB
admet-910	19	52	to	to	ADP
admet-910	19	53	.	.	PUNCT
admet-910	20	1	they	they	PRON
admet-910	20	2	conclude	conclude	VERB
admet-910	20	3	that	that	SCONJ
admet-910	20	4	the	the	DET
admet-910	20	5	current	current	ADJ
admet-910	20	6	models	model	NOUN
admet-910	20	7	are	be	AUX
admet-910	20	8	not	not	PART
admet-910	20	9	accurate	accurate	ADJ
admet-910	20	10	enough	enough	ADV
admet-910	20	11	for	for	ADP
admet-910	20	12	predictions	prediction	NOUN
admet-910	20	13	of	of	ADP
admet-910	20	14	this	this	DET
admet-910	20	15	type	type	NOUN
admet-910	20	16	of	of	ADP
admet-910	20	17	compounds	compound	NOUN
admet-910	20	18	and	and	CCONJ
admet-910	20	19	that	that	SCONJ
admet-910	20	20	the	the	DET
admet-910	20	21	solubility	solubility	NOUN
admet-910	20	22	models	model	NOUN
admet-910	20	23	need	need	VERB
admet-910	20	24	to	to	PART
admet-910	20	25	be	be	AUX
admet-910	20	26	developed	develop	VERB
admet-910	20	27	for	for	ADP
admet-910	20	28	this	this	DET
admet-910	20	29	chemical	chemical	ADJ
admet-910	20	30	space	space	NOUN
admet-910	20	31	.	.	PUNCT
admet-910	21	1	in	in	ADP
admet-910	21	2	relation	relation	NOUN
admet-910	21	3	to	to	ADP
admet-910	21	4	generation	generation	NOUN
admet-910	21	5	of	of	ADP
admet-910	21	6	more	more	ADJ
admet-910	21	7	predictive	predictive	ADJ
admet-910	21	8	solubility	solubility	NOUN
admet-910	21	9	models	model	NOUN
admet-910	21	10	,	,	PUNCT
admet-910	21	11	mitchell	mitchell	PROPN
admet-910	21	12	contributes	contribute	VERB
admet-910	21	13	with	with	ADP
admet-910	21	14	a	a	DET
admet-910	21	15	paper	paper	NOUN
admet-910	21	16	using	use	VERB
admet-910	21	17	three	three	NUM
admet-910	21	18	different	different	ADJ
admet-910	21	19	machine	machine	NOUN
admet-910	21	20	learning	learning	NOUN
admet-910	21	21	models	model	NOUN
admet-910	21	22	to	to	PART
admet-910	21	23	predict	predict	VERB
admet-910	21	24	the	the	DET
admet-910	21	25	‘	'	PUNCT
admet-910	21	26	2019	2019	NUM
admet-910	21	27	solubility	solubility	NOUN
admet-910	21	28	challenge	challenge	NOUN
admet-910	21	29	dataset	dataset	NOUN
admet-910	21	30	’	'	PUNCT
admet-910	22	1	[	[	X
admet-910	22	2	4	4	NUM
admet-910	22	3	]	]	PUNCT
admet-910	22	4	.	.	PUNCT
admet-910	23	1	it	it	PRON
admet-910	23	2	should	should	AUX
admet-910	23	3	be	be	AUX
admet-910	23	4	noted	note	VERB
admet-910	23	5	that	that	SCONJ
admet-910	23	6	this	this	DET
admet-910	23	7	dataset	dataset	NOUN
admet-910	23	8	is	be	AUX
admet-910	23	9	more	more	ADV
admet-910	23	10	traditional	traditional	ADJ
admet-910	23	11	,	,	PUNCT
admet-910	23	12	and	and	CCONJ
admet-910	23	13	biased	bias	VERB
admet-910	23	14	towards	towards	ADP
admet-910	23	15	the	the	DET
admet-910	23	16	small	small	ADJ
admet-910	23	17	molecule	molecule	NOUN
admet-910	23	18	space	space	NOUN
admet-910	23	19	,	,	PUNCT
admet-910	23	20	i.e.	i.e.	X
admet-910	23	21	not	not	PART
admet-910	23	22	the	the	DET
admet-910	23	23	bro5	bro5	NOUN
admet-910	23	24	space	space	NOUN
admet-910	23	25	.	.	PUNCT
admet-910	24	1	all	all	DET
admet-910	24	2	three	three	NUM
admet-910	24	3	models	model	NOUN
admet-910	24	4	were	be	AUX
admet-910	24	5	based	base	VERB
admet-910	24	6	on	on	ADP
admet-910	24	7	tree	tree	NOUN
admet-910	24	8	-	-	PUNCT
admet-910	24	9	like	like	ADJ
admet-910	24	10	classifiers	classifier	NOUN
admet-910	24	11	;	;	PUNCT
admet-910	24	12	rf	rf	VERB
admet-910	24	13	,	,	PUNCT
admet-910	24	14	the	the	DET
admet-910	24	15	extra	extra	ADJ
admet-910	24	16	trees	tree	NOUN
admet-910	24	17	algorithm	algorithm	NOUN
admet-910	24	18	,	,	PUNCT
admet-910	24	19	and	and	CCONJ
admet-910	24	20	a	a	DET
admet-910	24	21	consensus	consensus	NOUN
admet-910	24	22	model	model	NOUN
admet-910	24	23	of	of	ADP
admet-910	24	24	the	the	DET
admet-910	24	25	two	two	NUM
admet-910	24	26	.	.	PUNCT
admet-910	25	1	it	it	PRON
admet-910	25	2	was	be	AUX
admet-910	25	3	found	find	VERB
admet-910	25	4	the	the	DET
admet-910	25	5	extra	extra	ADJ
admet-910	25	6	trees	tree	NOUN
admet-910	25	7	provided	provide	VERB
admet-910	25	8	the	the	DET
admet-910	25	9	best	good	ADJ
admet-910	25	10	classifier	classifier	NOUN
admet-910	25	11	whereas	whereas	SCONJ
admet-910	25	12	both	both	PRON
admet-910	25	13	rf	rf	ADJ
admet-910	25	14	and	and	CCONJ
admet-910	25	15	the	the	DET
admet-910	25	16	consensus	consensus	NOUN
admet-910	25	17	model	model	NOUN
admet-910	25	18	were	be	AUX
admet-910	25	19	slightly	slightly	ADV
admet-910	25	20	better	well	ADJ
admet-910	25	21	for	for	ADP
admet-910	25	22	an	an	DET
admet-910	25	23	explored	explore	VERB
admet-910	25	24	test	test	NOUN
admet-910	25	25	set	set	NOUN
admet-910	25	26	.	.	PUNCT
admet-910	26	1	the	the	DET
admet-910	26	2	author	author	NOUN
admet-910	26	3	reports	report	VERB
admet-910	26	4	rmses	rmse	NOUN
admet-910	26	5	of	of	ADP
admet-910	26	6	0.95	0.95	NUM
admet-910	26	7	(	(	PUNCT
admet-910	26	8	tight	tight	ADJ
admet-910	26	9	dataset	dataset	NOUN
admet-910	26	10	;	;	PUNCT
admet-910	26	11	extra	extra	ADJ
admet-910	26	12	trees	tree	NOUN
admet-910	26	13	)	)	PUNCT
admet-910	26	14	and	and	CCONJ
admet-910	26	15	1.49	1.49	NUM
admet-910	26	16	(	(	PUNCT
admet-910	26	17	loose	loose	ADJ
admet-910	26	18	dataset	dataset	NOUN
admet-910	26	19	;	;	PUNCT
admet-910	26	20	rf	rf	ADJ
admet-910	26	21	/	/	SYM
admet-910	26	22	consensus	consensus	NOUN
admet-910	26	23	)	)	PUNCT
admet-910	26	24	indicating	indicate	VERB
admet-910	26	25	the	the	DET
admet-910	26	26	dependency	dependency	NOUN
admet-910	26	27	of	of	ADP
admet-910	26	28	the	the	DET
admet-910	26	29	chemical	chemical	NOUN
admet-910	26	30	space	space	NOUN
admet-910	26	31	explored	explore	VERB
admet-910	26	32	.	.	PUNCT
admet-910	27	1	falcón	falcón	PROPN
admet-910	27	2	-	-	PUNCT
admet-910	27	3	cano	cano	PROPN
admet-910	27	4	et	et	NOUN
admet-910	27	5	al	al	PROPN
admet-910	27	6	.	.	PUNCT
admet-910	28	1	[	[	X
admet-910	28	2	5	5	NUM
admet-910	28	3	]	]	PUNCT
admet-910	28	4	also	also	ADV
admet-910	28	5	explored	explore	VERB
admet-910	28	6	rf	rf	PRON
admet-910	28	7	approaches	approach	NOUN
admet-910	28	8	and	and	CCONJ
admet-910	28	9	consensus	consensus	NOUN
admet-910	28	10	modelling	modelling	NOUN
admet-910	28	11	to	to	PART
admet-910	28	12	predict	predict	VERB
admet-910	28	13	solubility	solubility	NOUN
admet-910	28	14	,	,	PUNCT
admet-910	28	15	with	with	ADP
admet-910	28	16	focus	focus	NOUN
admet-910	28	17	on	on	ADP
admet-910	28	18	generating	generate	VERB
admet-910	28	19	better	well	ADJ
admet-910	28	20	algorithms	algorithm	NOUN
admet-910	28	21	and	and	CCONJ
admet-910	28	22	improved	improve	VERB
admet-910	28	23	work	work	NOUN
admet-910	28	24	-	-	PUNCT
admet-910	28	25	flow	flow	NOUN
admet-910	28	26	during	during	ADP
admet-910	28	27	the	the	DET
admet-910	28	28	modelling	modelling	NOUN
admet-910	28	29	for	for	ADP
admet-910	28	30	data	data	NOUN
admet-910	28	31	curation	curation	NOUN
admet-910	28	32	and	and	CCONJ
admet-910	28	33	variable	variable	ADJ
admet-910	28	34	selection	selection	NOUN
admet-910	28	35	.	.	PUNCT
admet-910	29	1	in	in	ADP
admet-910	29	2	their	their	PRON
admet-910	29	3	study	study	NOUN
admet-910	29	4	the	the	DET
admet-910	29	5	reported	report	VERB
admet-910	29	6	rmse	rmse	NOUN
admet-910	29	7	of	of	ADP
admet-910	29	8	the	the	DET
admet-910	29	9	generated	generate	VERB
admet-910	29	10	model	model	NOUN
admet-910	29	11	is	be	AUX
admet-910	29	12	0.93	0.93	NUM
admet-910	29	13	log	log	NOUN
admet-910	29	14	units	unit	NOUN
admet-910	29	15	for	for	ADP
admet-910	29	16	the	the	DET
admet-910	29	17	test	test	NOUN
admet-910	29	18	set	set	NOUN
admet-910	29	19	taken	take	VERB
admet-910	29	20	from	from	ADP
admet-910	29	21	the	the	DET
admet-910	29	22	solubility	solubility	NOUN
admet-910	29	23	challenge	challenge	NOUN
admet-910	29	24	dataset	dataset	VERB
admet-910	29	25	.	.	PUNCT
admet-910	30	1	the	the	DET
admet-910	30	2	authors	author	NOUN
admet-910	30	3	also	also	ADV
admet-910	30	4	contrast	contrast	VERB
admet-910	30	5	their	their	PRON
admet-910	30	6	models	model	NOUN
admet-910	30	7	to	to	ADP
admet-910	30	8	other	other	ADJ
admet-910	30	9	solubility	solubility	NOUN
admet-910	30	10	models	model	NOUN
admet-910	30	11	,	,	PUNCT
admet-910	30	12	providing	provide	VERB
admet-910	30	13	an	an	DET
admet-910	30	14	updated	update	VERB
admet-910	30	15	view	view	NOUN
admet-910	30	16	on	on	ADP
admet-910	30	17	the	the	DET
admet-910	30	18	standing	standing	NOUN
admet-910	30	19	of	of	ADP
admet-910	30	20	this	this	DET
admet-910	30	21	field	field	NOUN
admet-910	30	22	.	.	PUNCT
admet-910	31	1	improved	improve	VERB
admet-910	31	2	modelling	modelling	NOUN
admet-910	31	3	approaches	approach	NOUN
admet-910	31	4	are	be	AUX
admet-910	31	5	further	far	ADV
admet-910	31	6	studied	study	VERB
admet-910	31	7	by	by	ADP
admet-910	31	8	mecklenfeld	mecklenfeld	NOUN
admet-910	31	9	and	and	CCONJ
admet-910	31	10	raabe	raabe	NOUN
admet-910	32	1	[	[	X
admet-910	32	2	6	6	NUM
admet-910	32	3	]	]	PUNCT
admet-910	32	4	.	.	PUNCT
admet-910	33	1	they	they	PRON
admet-910	33	2	embarked	embark	VERB
admet-910	33	3	on	on	ADP
admet-910	33	4	a	a	DET
admet-910	33	5	study	study	NOUN
admet-910	33	6	to	to	PART
admet-910	33	7	optimise	optimise	VERB
admet-910	33	8	the	the	DET
admet-910	33	9	force	force	NOUN
admet-910	33	10	field	field	NOUN
admet-910	33	11	parameters	parameter	NOUN
admet-910	33	12	used	use	VERB
admet-910	33	13	for	for	ADP
admet-910	33	14	solvation	solvation	NOUN
admet-910	33	15	energy	energy	NOUN
admet-910	33	16	calculations	calculation	NOUN
admet-910	33	17	.	.	PUNCT
admet-910	34	1	they	they	PRON
admet-910	34	2	developed	develop	VERB
admet-910	34	3	and	and	CCONJ
admet-910	34	4	validated	validate	VERB
admet-910	34	5	general	general	ADJ
admet-910	34	6	amber	amber	PROPN
admet-910	34	7	force	force	PROPN
admet-910	34	8	field	field	PROPN
admet-910	34	9	(	(	PUNCT
admet-910	34	10	gaff	gaff	NOUN
admet-910	34	11	)	)	PUNCT
admet-910	34	12	parameters	parameter	NOUN
admet-910	34	13	by	by	ADP
admet-910	34	14	taking	take	VERB
admet-910	34	15	into	into	ADP
admet-910	34	16	account	account	NOUN
admet-910	34	17	the	the	DET
admet-910	34	18	lennard	lennard	PROPN
admet-910	34	19	-	-	PUNCT
admet-910	34	20	jones	jones	PROPN
admet-910	34	21	parameters	parameter	NOUN
admet-910	34	22	in	in	ADP
admet-910	34	23	combination	combination	NOUN
admet-910	34	24	with	with	ADP
admet-910	34	25	implicit	implicit	ADJ
admet-910	34	26	polarized	polarize	VERB
admet-910	34	27	charges	charge	NOUN
admet-910	34	28	.	.	PUNCT
admet-910	35	1	the	the	DET
admet-910	35	2	validation	validation	NOUN
admet-910	35	3	was	be	AUX
admet-910	35	4	performed	perform	VERB
admet-910	35	5	by	by	ADP
admet-910	35	6	making	make	VERB
admet-910	35	7	use	use	NOUN
admet-910	35	8	of	of	ADP
admet-910	35	9	142	142	NUM
admet-910	35	10	free	free	ADJ
admet-910	35	11	energies	energy	NOUN
admet-910	35	12	and	and	CCONJ
admet-910	35	13	100	100	NUM
admet-910	35	14	densities	density	NOUN
admet-910	35	15	of	of	ADP
admet-910	35	16	binary	binary	ADJ
admet-910	35	17	mixtures	mixture	NOUN
admet-910	35	18	and	and	CCONJ
admet-910	35	19	resulted	result	VERB
admet-910	35	20	in	in	ADP
admet-910	35	21	improved	improved	ADJ
admet-910	35	22	models	model	NOUN
admet-910	35	23	of	of	ADP
admet-910	35	24	relative	relative	ADJ
admet-910	35	25	solubilities	solubility	NOUN
admet-910	35	26	and	and	CCONJ
admet-910	35	27	fluid	fluid	ADJ
admet-910	35	28	phase	phase	NOUN
admet-910	35	29	behaviour	behaviour	NOUN
admet-910	35	30	.	.	PUNCT
admet-910	36	1	the	the	DET
admet-910	36	2	final	final	ADJ
admet-910	36	3	two	two	NUM
admet-910	36	4	papers	paper	NOUN
admet-910	36	5	in	in	ADP
admet-910	36	6	the	the	DET
admet-910	36	7	first	first	ADJ
admet-910	36	8	special	special	ADJ
admet-910	36	9	issue	issue	NOUN
admet-910	36	10	focus	focus	VERB
admet-910	36	11	on	on	ADP
admet-910	36	12	mathematical	mathematical	ADJ
admet-910	36	13	models	model	NOUN
admet-910	36	14	of	of	ADP
admet-910	36	15	dissolution	dissolution	NOUN
admet-910	36	16	of	of	ADP
admet-910	36	17	particles	particle	NOUN
admet-910	36	18	and	and	CCONJ
admet-910	36	19	gastrointestinal	gastrointestinal	ADJ
admet-910	36	20	motility	motility	NOUN
admet-910	36	21	.	.	PUNCT
admet-910	37	1	grassi	grassi	PROPN
admet-910	37	2	and	and	CCONJ
admet-910	37	3	coworkers	coworker	NOUN
admet-910	37	4	[	[	X
admet-910	37	5	7	7	NUM
admet-910	37	6	]	]	PUNCT
admet-910	37	7	described	describe	VERB
admet-910	37	8	dissolution	dissolution	NOUN
admet-910	37	9	of	of	ADP
admet-910	37	10	poly	poly	NOUN
admet-910	37	11	-	-	PUNCT
admet-910	37	12	dispersed	disperse	VERB
admet-910	37	13	particles	particle	NOUN
admet-910	37	14	in	in	ADP
admet-910	37	15	a	a	DET
admet-910	37	16	finite	finite	ADJ
admet-910	37	17	liquid	liquid	ADJ
admet-910	37	18	environment	environment	NOUN
admet-910	37	19	,	,	PUNCT
admet-910	37	20	and	and	CCONJ
admet-910	37	21	developed	develop	VERB
admet-910	37	22	two	two	NUM
admet-910	37	23	different	different	ADJ
admet-910	37	24	equations	equation	NOUN
admet-910	37	25	that	that	PRON
admet-910	37	26	take	take	VERB
admet-910	37	27	into	into	ADP
admet-910	37	28	consideration	consideration	NOUN
admet-910	37	29	size	size	NOUN
admet-910	37	30	reduction	reduction	NOUN
admet-910	37	31	,	,	PUNCT
admet-910	37	32	polydispersity	polydispersity	NOUN
admet-910	37	33	and	and	CCONJ
admet-910	37	34	particle	particle	NOUN
admet-910	37	35	geometry	geometry	NOUN
admet-910	37	36	(	(	PUNCT
admet-910	37	37	spherical	spherical	ADJ
admet-910	37	38	,	,	PUNCT
admet-910	37	39	cylindrical	cylindrical	ADJ
admet-910	37	40	and	and	CCONJ
admet-910	37	41	parallelepided	parallelepide	VERB
admet-910	37	42	)	)	PUNCT
admet-910	37	43	.	.	PUNCT
admet-910	38	1	these	these	DET
admet-910	38	2	mathematical	mathematical	ADJ
admet-910	38	3	models	model	NOUN
admet-910	38	4	are	be	AUX
admet-910	38	5	useful	useful	ADJ
admet-910	38	6	to	to	ADP
admet-910	38	7	,	,	PUNCT
admet-910	38	8	among	among	ADP
admet-910	38	9	others	other	NOUN
admet-910	38	10	,	,	PUNCT
admet-910	38	11	early	early	ADV
admet-910	38	12	evaluate	evaluate	VERB
admet-910	38	13	the	the	DET
admet-910	38	14	importance	importance	NOUN
admet-910	38	15	of	of	ADP
admet-910	38	16	wettability	wettability	NOUN
admet-910	38	17	for	for	ADP
admet-910	38	18	the	the	DET
admet-910	38	19	dissolution	dissolution	NOUN
admet-910	38	20	process	process	NOUN
admet-910	38	21	.	.	PUNCT
admet-910	39	1	johnson	johnson	PROPN
admet-910	39	2	also	also	ADV
admet-910	39	3	models	model	VERB
admet-910	39	4	dissolution	dissolution	ADJ
admet-910	39	5	by	by	ADP
admet-910	39	6	coupling	couple	VERB
admet-910	39	7	the	the	DET
admet-910	39	8	dissolution	dissolution	ADJ
admet-910	39	9	process	process	NOUN
admet-910	39	10	to	to	ADP
admet-910	39	11	the	the	DET
admet-910	39	12	gastrointestinal	gastrointestinal	ADJ
admet-910	39	13	motility	motility	NOUN
admet-910	39	14	[	[	X
admet-910	39	15	8	8	NUM
admet-910	39	16	]	]	PUNCT
admet-910	39	17	.	.	PUNCT
admet-910	40	1	in	in	ADP
admet-910	40	2	this	this	DET
admet-910	40	3	work	work	NOUN
admet-910	40	4	,	,	PUNCT
admet-910	40	5	the	the	DET
admet-910	40	6	multiple	multiple	ADJ
admet-910	40	7	moving	move	VERB
admet-910	40	8	plug	plug	NOUN
admet-910	40	9	model	model	NOUN
admet-910	40	10	was	be	AUX
admet-910	40	11	described	describe	VERB
admet-910	40	12	and	and	CCONJ
admet-910	40	13	used	use	VERB
admet-910	40	14	to	to	PART
admet-910	40	15	simulate	simulate	VERB
admet-910	40	16	the	the	DET
admet-910	40	17	effect	effect	NOUN
admet-910	40	18	of	of	ADP
admet-910	40	19	the	the	DET
admet-910	40	20	gi	gi	NOUN
admet-910	40	21	motility	motility	NOUN
admet-910	40	22	and	and	CCONJ
admet-910	40	23	particle	particle	NOUN
admet-910	40	24	dissolution	dissolution	NOUN
admet-910	40	25	on	on	ADP
admet-910	40	26	the	the	DET
admet-910	40	27	resulting	result	VERB
admet-910	40	28	pharmacokinetic	pharmacokinetic	ADJ
admet-910	40	29	profile	profile	NOUN
admet-910	40	30	of	of	ADP
admet-910	40	31	the	the	DET
admet-910	40	32	compound	compound	NOUN
admet-910	40	33	.	.	PUNCT
admet-910	41	1	this	this	DET
admet-910	41	2	work	work	NOUN
admet-910	41	3	builds	build	VERB
admet-910	41	4	on	on	ADP
admet-910	41	5	the	the	DET
admet-910	41	6	experimental	experimental	ADJ
admet-910	41	7	evidence	evidence	NOUN
admet-910	41	8	that	that	SCONJ
admet-910	41	9	the	the	DET
admet-910	41	10	gi	gi	NOUN
admet-910	41	11	fluid	fluid	NOUN
admet-910	41	12	exists	exist	VERB
admet-910	41	13	in	in	ADP
admet-910	41	14	water	water	NOUN
admet-910	41	15	pockets	pocket	NOUN
admet-910	41	16	,	,	PUNCT
admet-910	41	17	and	and	CCONJ
admet-910	41	18	hence	hence	ADV
admet-910	41	19	,	,	PUNCT
admet-910	41	20	the	the	DET
admet-910	41	21	model	model	NOUN
admet-910	41	22	provides	provide	VERB
admet-910	41	23	a	a	DET
admet-910	41	24	more	more	ADV
admet-910	41	25	physiologically	physiologically	ADV
admet-910	41	26	relevant	relevant	ADJ
admet-910	41	27	approach	approach	NOUN
admet-910	41	28	to	to	PART
admet-910	41	29	explore	explore	VERB
admet-910	41	30	the	the	DET
admet-910	41	31	dissolution	dissolution	NOUN
admet-910	41	32	process	process	NOUN
admet-910	41	33	in	in	ADP
admet-910	41	34	vivo	vivo	NOUN
admet-910	41	35	.	.	PUNCT
admet-910	42	1	in	in	ADP
admet-910	42	2	the	the	DET
admet-910	42	3	second	second	ADJ
admet-910	42	4	issue	issue	NOUN
admet-910	42	5	focus	focus	NOUN
admet-910	42	6	is	be	AUX
admet-910	42	7	shifted	shift	VERB
admet-910	42	8	towards	towards	ADP
admet-910	42	9	experimental	experimental	ADJ
admet-910	42	10	assessment	assessment	NOUN
admet-910	42	11	and	and	CCONJ
admet-910	42	12	technologies	technology	NOUN
admet-910	42	13	for	for	ADP
admet-910	42	14	profiling	profiling	NOUN
admet-910	42	15	and	and	CCONJ
admet-910	42	16	enabling	enable	VERB
admet-910	42	17	absorption	absorption	NOUN
admet-910	42	18	of	of	ADP
admet-910	42	19	poorly	poorly	ADJ
admet-910	42	20	-	-	PUNCT
admet-910	42	21	water	water	NOUN
admet-910	42	22	soluble	soluble	ADJ
admet-910	42	23	compounds	compound	NOUN
admet-910	42	24	.	.	PUNCT
admet-910	43	1	a	a	DET
admet-910	43	2	series	series	NOUN
admet-910	43	3	of	of	ADP
admet-910	43	4	extensive	extensive	ADJ
admet-910	43	5	reviews	review	NOUN
admet-910	43	6	are	be	AUX
admet-910	43	7	provided	provide	VERB
admet-910	43	8	in	in	ADP
admet-910	43	9	this	this	DET
admet-910	43	10	special	special	ADJ
admet-910	43	11	issue	issue	NOUN
admet-910	43	12	,	,	PUNCT
admet-910	43	13	describing	describe	VERB
admet-910	43	14	the	the	DET
admet-910	43	15	current	current	ADJ
admet-910	43	16	standing	standing	NOUN
admet-910	43	17	of	of	ADP
admet-910	43	18	electrospun	electrospun	NOUN
admet-910	43	19	nanofibers	nanofiber	NOUN
admet-910	43	20	for	for	ADP
admet-910	43	21	drug	drug	NOUN
admet-910	43	22	delivery	delivery	NOUN
admet-910	43	23	and	and	CCONJ
admet-910	43	24	optimised	optimise	VERB
admet-910	43	25	dissolution	dissolution	NOUN
admet-910	43	26	profiles	profile	NOUN
admet-910	43	27	[	[	X
admet-910	43	28	9	9	NUM
admet-910	43	29	]	]	PUNCT
admet-910	43	30	,	,	PUNCT
admet-910	43	31	supercritical	supercritical	ADJ
admet-910	43	32	fluid	fluid	ADJ
admet-910	43	33	technology	technology	NOUN
admet-910	43	34	for	for	ADP
admet-910	43	35	controlled	control	VERB
admet-910	43	36	production	production	NOUN
admet-910	43	37	of	of	ADP
admet-910	43	38	nanoand	nanoand	NOUN
admet-910	43	39	microparticles	microparticle	NOUN
admet-910	43	40	of	of	ADP
admet-910	43	41	poorly	poorly	ADV
admet-910	43	42	soluble	soluble	ADJ
admet-910	43	43	compounds	compound	NOUN
admet-910	43	44	[	[	X
admet-910	43	45	10	10	NUM
admet-910	43	46	]	]	PUNCT
admet-910	43	47	,	,	PUNCT
admet-910	43	48	nanoparticles	nanoparticle	NOUN
admet-910	43	49	and	and	CCONJ
admet-910	43	50	their	their	PRON
admet-910	43	51	in	in	ADP
admet-910	43	52	vivo	vivo	ADJ
admet-910	43	53	performance	performance	NOUN
admet-910	43	54	[	[	X
admet-910	43	55	11	11	NUM
admet-910	43	56	]	]	PUNCT
admet-910	43	57	and	and	CCONJ
admet-910	43	58	solubility	solubility	NOUN
admet-910	43	59	aspects	aspect	NOUN
admet-910	43	60	for	for	ADP
admet-910	43	61	proteins	protein	NOUN
admet-910	43	62	[	[	X
admet-910	43	63	12	12	NUM
admet-910	43	64	]	]	PUNCT
admet-910	43	65	.	.	PUNCT
admet-910	44	1	in	in	ADP
admet-910	44	2	addition	addition	NOUN
admet-910	44	3	to	to	ADP
admet-910	44	4	these	these	DET
admet-910	44	5	timely	timely	ADJ
admet-910	44	6	reviews	review	NOUN
admet-910	44	7	on	on	ADP
admet-910	44	8	important	important	ADJ
admet-910	44	9	topics	topic	NOUN
admet-910	44	10	for	for	ADP
admet-910	44	11	solubility	solubility	NOUN
admet-910	44	12	,	,	PUNCT
admet-910	44	13	dissolution	dissolution	NOUN
admet-910	44	14	and	and	CCONJ
admet-910	44	15	enabling	enable	VERB
admet-910	44	16	formualations	formualation	NOUN
admet-910	44	17	,	,	PUNCT
admet-910	44	18	papers	paper	NOUN
admet-910	44	19	describing	describe	VERB
admet-910	44	20	original	original	ADJ
admet-910	44	21	research	research	NOUN
admet-910	44	22	on	on	ADP
admet-910	44	23	assessment	assessment	NOUN
admet-910	44	24	and	and	CCONJ
admet-910	44	25	drug	drug	NOUN
admet-910	44	26	delivery	delivery	NOUN
admet-910	44	27	of	of	ADP
admet-910	44	28	poorly	poorly	ADV
admet-910	44	29	soluble	soluble	ADJ
admet-910	44	30	compounds	compound	NOUN
admet-910	44	31	are	be	AUX
admet-910	44	32	included	include	VERB
admet-910	44	33	.	.	PUNCT
admet-910	45	1	štukelj	štukelj	VERB
admet-910	45	2	et	et	PROPN
admet-910	45	3	al	al	PROPN
admet-910	45	4	.	.	PUNCT
admet-910	46	1	[	[	X
admet-910	46	2	13	13	NUM
admet-910	46	3	]	]	PUNCT
admet-910	46	4	describes	describe	VERB
admet-910	46	5	a	a	DET
admet-910	46	6	new	new	ADJ
admet-910	46	7	methodology	methodology	NOUN
admet-910	46	8	to	to	PART
admet-910	46	9	determine	determine	VERB
admet-910	46	10	dissolution	dissolution	NOUN
admet-910	46	11	of	of	ADP
admet-910	46	12	amorphous	amorphous	ADJ
admet-910	46	13	powders	powder	NOUN
admet-910	46	14	based	base	VERB
admet-910	46	15	on	on	ADP
admet-910	46	16	image	image	NOUN
admet-910	46	17	analysis	analysis	NOUN
admet-910	46	18	.	.	PUNCT
admet-910	47	1	in	in	ADP
admet-910	47	2	this	this	DET
admet-910	47	3	work	work	NOUN
admet-910	47	4	,	,	PUNCT
admet-910	47	5	image	image	NOUN
admet-910	47	6	-	-	PUNCT
admet-910	47	7	based	base	VERB
admet-910	47	8	single	single	ADJ
admet-910	47	9	particle	particle	NOUN
admet-910	47	10	analysis	analysis	NOUN
admet-910	47	11	was	be	AUX
admet-910	47	12	used	use	VERB
admet-910	47	13	to	to	PART
admet-910	47	14	study	study	VERB
admet-910	47	15	dissolution	dissolution	NOUN
admet-910	47	16	of	of	ADP
admet-910	47	17	amorphous	amorphous	ADJ
admet-910	47	18	indomethacin	indomethacin	NOUN
admet-910	47	19	over	over	ADP
admet-910	47	20	time	time	NOUN
admet-910	47	21	and	and	CCONJ
admet-910	47	22	the	the	DET
admet-910	47	23	results	result	NOUN
admet-910	47	24	were	be	AUX
admet-910	47	25	compared	compare	VERB
admet-910	47	26	to	to	ADP
admet-910	47	27	powder	powder	NOUN
admet-910	47	28	xrd	xrd	NOUN
admet-910	47	29	analysis	analysis	NOUN
admet-910	47	30	.	.	PUNCT
admet-910	48	1	the	the	DET
admet-910	48	2	single	single	ADJ
admet-910	48	3	particle	particle	NOUN
admet-910	48	4	analysis	analysis	NOUN
admet-910	48	5	was	be	AUX
admet-910	48	6	useful	useful	ADJ
admet-910	48	7	to	to	PART
admet-910	48	8	study	study	VERB
admet-910	48	9	local	local	ADJ
admet-910	48	10	recrystallization	recrystallization	NOUN
admet-910	48	11	occurring	occur	VERB
admet-910	48	12	on	on	ADP
admet-910	48	13	the	the	DET
admet-910	48	14	particle	particle	NOUN
admet-910	48	15	surface	surface	NOUN
admet-910	48	16	,	,	PUNCT
admet-910	48	17	providing	provide	VERB
admet-910	48	18	crucial	crucial	ADJ
admet-910	48	19	information	information	NOUN
admet-910	48	20	to	to	PART
admet-910	48	21	understand	understand	VERB
admet-910	48	22	surface	surface	NOUN
admet-910	48	23	chemistry	chemistry	NOUN
admet-910	48	24	effects	effect	NOUN
admet-910	48	25	during	during	ADP
admet-910	48	26	storage	storage	NOUN
admet-910	48	27	and	and	CCONJ
admet-910	48	28	dissolution	dissolution	NOUN
admet-910	48	29	.	.	PUNCT
admet-910	49	1	dissolution	dissolution	PROPN
admet-910	49	2	was	be	AUX
admet-910	49	3	also	also	ADV
admet-910	49	4	studied	study	VERB
admet-910	49	5	by	by	ADP
admet-910	49	6	gigante	gigante	PROPN
admet-910	49	7	et	et	PROPN
admet-910	49	8	al	al	PROPN
admet-910	49	9	.	.	PUNCT
admet-910	50	1	[	[	X
admet-910	50	2	14	14	NUM
admet-910	50	3	]	]	PUNCT
admet-910	50	4	who	who	PRON
admet-910	50	5	set	set	VERB
admet-910	50	6	out	out	ADP
admet-910	50	7	to	to	PART
admet-910	50	8	perform	perform	VERB
admet-910	50	9	a	a	DET
admet-910	50	10	global	global	ADJ
admet-910	50	11	evaluation	evaluation	NOUN
admet-910	50	12	of	of	ADP
admet-910	50	13	https://doi.org/10.5599/admet.910	https://doi.org/10.5599/admet.910	NOUN
admet-910	51	1	c.	c.	PROPN
admet-910	51	2	bergström	bergström	PROPN
admet-910	51	3	and	and	CCONJ
admet-910	51	4	a.	a.	PROPN
admet-910	51	5	llinas	llinas	PROPN
admet-910	51	6	admet	admet	PROPN
admet-910	51	7	&	&	CCONJ
admet-910	51	8	dmpk	dmpk	PROPN
admet-910	51	9	8(3	8(3	NUM
admet-910	51	10	)	)	PUNCT
admet-910	51	11	(	(	PUNCT
admet-910	51	12	2020	2020	NUM
admet-910	51	13	)	)	PUNCT
admet-910	51	14	176	176	NUM
admet-910	51	15	-	-	SYM
admet-910	51	16	179	179	NUM
admet-910	51	17	178	178	NUM
admet-910	51	18	the	the	PRON
admet-910	51	19	who	who	PRON
admet-910	51	20	harmonised	harmonise	VERB
admet-910	51	21	protocol	protocol	NOUN
admet-910	51	22	for	for	ADP
admet-910	51	23	equilibrium	equilibrium	NOUN
admet-910	51	24	solubility	solubility	NOUN
admet-910	51	25	experiments	experiment	NOUN
admet-910	51	26	.	.	PUNCT
admet-910	52	1	the	the	DET
admet-910	52	2	study	study	NOUN
admet-910	52	3	focused	focus	VERB
admet-910	52	4	on	on	ADP
admet-910	52	5	measurement	measurement	NOUN
admet-910	52	6	of	of	ADP
admet-910	52	7	16	16	NUM
admet-910	52	8	compounds	compound	NOUN
admet-910	52	9	for	for	ADP
admet-910	52	10	which	which	PRON
admet-910	52	11	the	the	DET
admet-910	52	12	biopharmaceutics	biopharmaceutics	NOUN
admet-910	52	13	classification	classification	NOUN
admet-910	52	14	had	have	AUX
admet-910	52	15	previously	previously	ADV
admet-910	52	16	been	be	AUX
admet-910	52	17	performed	perform	VERB
admet-910	52	18	.	.	PUNCT
admet-910	53	1	they	they	PRON
admet-910	53	2	successfully	successfully	ADV
admet-910	53	3	validated	validate	VERB
admet-910	53	4	the	the	DET
admet-910	53	5	current	current	ADJ
admet-910	53	6	protocol	protocol	NOUN
admet-910	53	7	in	in	ADP
admet-910	53	8	this	this	DET
admet-910	53	9	extensive	extensive	ADJ
admet-910	53	10	collaboration	collaboration	NOUN
admet-910	53	11	involving	involve	VERB
admet-910	53	12	11	11	NUM
admet-910	53	13	laboratories	laboratory	NOUN
admet-910	53	14	worldwide	worldwide	ADV
admet-910	53	15	.	.	PUNCT
admet-910	54	1	the	the	DET
admet-910	54	2	study	study	NOUN
admet-910	54	3	also	also	ADV
admet-910	54	4	indicates	indicate	VERB
admet-910	54	5	that	that	SCONJ
admet-910	54	6	some	some	DET
admet-910	54	7	compounds	compound	NOUN
admet-910	54	8	may	may	AUX
admet-910	54	9	have	have	AUX
admet-910	54	10	been	be	AUX
admet-910	54	11	sorted	sort	VERB
admet-910	54	12	into	into	ADP
admet-910	54	13	the	the	DET
admet-910	54	14	wrong	wrong	ADJ
admet-910	54	15	bcs	bcs	NOUN
admet-910	54	16	class	class	NOUN
admet-910	54	17	in	in	ADP
admet-910	54	18	previous	previous	ADJ
admet-910	54	19	studies	study	NOUN
admet-910	54	20	,	,	PUNCT
admet-910	54	21	meriting	merit	VERB
admet-910	54	22	further	further	ADJ
admet-910	54	23	exploration	exploration	NOUN
admet-910	54	24	.	.	PUNCT
admet-910	55	1	dissolution	dissolution	ADJ
admet-910	55	2	evaluation	evaluation	NOUN
admet-910	55	3	of	of	ADP
admet-910	55	4	furosemide	furosemide	ADJ
admet-910	55	5	products	product	NOUN
admet-910	55	6	was	be	AUX
admet-910	55	7	performed	perform	VERB
admet-910	55	8	by	by	ADP
admet-910	55	9	medina	medina	PROPN
admet-910	55	10	-	-	PUNCT
admet-910	55	11	lopéz	lopéz	PROPN
admet-910	55	12	and	and	CCONJ
admet-910	55	13	coworkers	coworker	NOUN
admet-910	55	14	[	[	X
admet-910	55	15	15	15	NUM
admet-910	55	16	]	]	PUNCT
admet-910	55	17	.	.	PUNCT
admet-910	56	1	they	they	PRON
admet-910	56	2	studied	study	VERB
admet-910	56	3	dissolution	dissolution	NOUN
admet-910	56	4	for	for	ADP
admet-910	56	5	furosemide	furosemide	ADJ
admet-910	56	6	reference	reference	NOUN
admet-910	56	7	tablets	tablet	NOUN
admet-910	56	8	in	in	ADP
admet-910	56	9	usp	usp	NOUN
admet-910	56	10	apparatus	apparatus	NOUN
admet-910	56	11	1	1	NUM
admet-910	56	12	,	,	PUNCT
admet-910	56	13	2	2	NUM
admet-910	56	14	and	and	CCONJ
admet-910	56	15	4	4	NUM
admet-910	56	16	,	,	PUNCT
admet-910	56	17	under	under	ADP
admet-910	56	18	different	different	ADJ
admet-910	56	19	experimental	experimental	ADJ
admet-910	56	20	conditions	condition	NOUN
admet-910	56	21	.	.	PUNCT
admet-910	57	1	they	they	PRON
admet-910	57	2	observed	observe	VERB
admet-910	57	3	statistically	statistically	ADV
admet-910	57	4	significant	significant	ADJ
admet-910	57	5	differences	difference	NOUN
admet-910	57	6	between	between	ADP
admet-910	57	7	usp	usp	NOUN
admet-910	57	8	apparatus	apparatus	NOUN
admet-910	57	9	1	1	NUM
admet-910	57	10	and	and	CCONJ
admet-910	57	11	2	2	NUM
admet-910	57	12	,	,	PUNCT
admet-910	57	13	whereas	whereas	SCONJ
admet-910	57	14	conditions	condition	NOUN
admet-910	57	15	producing	produce	VERB
admet-910	57	16	similar	similar	ADJ
admet-910	57	17	dissolution	dissolution	NOUN
admet-910	57	18	profiles	profile	NOUN
admet-910	57	19	for	for	ADP
admet-910	57	20	usp	usp	NOUN
admet-910	57	21	apparatus	apparatus	NOUN
admet-910	57	22	2	2	NUM
admet-910	57	23	and	and	CCONJ
admet-910	57	24	4	4	NUM
admet-910	57	25	were	be	AUX
admet-910	57	26	identified	identify	VERB
admet-910	57	27	.	.	PUNCT
admet-910	58	1	in	in	ADP
admet-910	58	2	the	the	DET
admet-910	58	3	paper	paper	NOUN
admet-910	58	4	authored	author	VERB
admet-910	58	5	by	by	ADP
admet-910	58	6	isvoran	isvoran	NOUN
admet-910	58	7	et	et	PROPN
admet-910	58	8	al	al	PROPN
admet-910	58	9	.	.	PUNCT
admet-910	59	1	[	[	X
admet-910	59	2	16	16	NUM
admet-910	59	3	]	]	X
admet-910	59	4	solubility	solubility	NOUN
admet-910	59	5	of	of	ADP
admet-910	59	6	short	short	ADJ
admet-910	59	7	oligomers	oligomer	NOUN
admet-910	59	8	of	of	ADP
admet-910	59	9	lactic	lactic	ADJ
admet-910	59	10	acid	acid	NOUN
admet-910	59	11	is	be	AUX
admet-910	59	12	studied	study	VERB
admet-910	59	13	.	.	PUNCT
admet-910	60	1	polylactic	polylactic	ADJ
admet-910	60	2	acid	acid	NOUN
admet-910	60	3	has	have	VERB
admet-910	60	4	potential	potential	NOUN
admet-910	60	5	to	to	PART
admet-910	60	6	be	be	AUX
admet-910	60	7	used	use	VERB
admet-910	60	8	in	in	ADP
admet-910	60	9	medical	medical	ADJ
admet-910	60	10	applications	application	NOUN
admet-910	60	11	,	,	PUNCT
admet-910	60	12	and	and	CCONJ
admet-910	60	13	hence	hence	ADV
admet-910	60	14	the	the	DET
admet-910	60	15	solubility	solubility	NOUN
admet-910	60	16	of	of	ADP
admet-910	60	17	this	this	DET
admet-910	60	18	polymer	polymer	NOUN
admet-910	60	19	is	be	AUX
admet-910	60	20	important	important	ADJ
admet-910	60	21	.	.	PUNCT
admet-910	61	1	the	the	DET
admet-910	61	2	authors	author	NOUN
admet-910	61	3	conclude	conclude	VERB
admet-910	61	4	that	that	SCONJ
admet-910	61	5	solubility	solubility	NOUN
admet-910	61	6	decreases	decrease	VERB
admet-910	61	7	linearly	linearly	ADV
admet-910	61	8	with	with	ADP
admet-910	61	9	increased	increase	VERB
admet-910	61	10	molecular	molecular	ADJ
admet-910	61	11	weight	weight	NOUN
admet-910	61	12	and	and	CCONJ
admet-910	61	13	that	that	SCONJ
admet-910	61	14	the	the	DET
admet-910	61	15	short	short	ADJ
admet-910	61	16	oligomers	oligomer	NOUN
admet-910	61	17	have	have	AUX
admet-910	61	18	limited	limit	VERB
admet-910	61	19	toxicology	toxicology	NOUN
admet-910	61	20	but	but	CCONJ
admet-910	61	21	potentially	potentially	ADV
admet-910	61	22	may	may	AUX
admet-910	61	23	interact	interact	VERB
admet-910	61	24	with	with	ADP
admet-910	61	25	organic	organic	ADJ
admet-910	61	26	anion	anion	NOUN
admet-910	61	27	transportrs	transportrs	NOUN
admet-910	61	28	(	(	PUNCT
admet-910	61	29	oatp1b1	oatp1b1	NUM
admet-910	61	30	and	and	CCONJ
admet-910	61	31	oatp1b3	oatp1b3	NOUN
admet-910	61	32	)	)	PUNCT
admet-910	61	33	.	.	PUNCT
admet-910	62	1	the	the	DET
admet-910	62	2	final	final	ADJ
admet-910	62	3	contribution	contribution	NOUN
admet-910	62	4	to	to	ADP
admet-910	62	5	this	this	DET
admet-910	62	6	special	special	ADJ
admet-910	62	7	issue	issue	NOUN
admet-910	62	8	is	be	AUX
admet-910	62	9	a	a	DET
admet-910	62	10	paper	paper	NOUN
admet-910	62	11	by	by	ADP
admet-910	62	12	prestidge	prestidge	NOUN
admet-910	62	13	et	et	PROPN
admet-910	62	14	al	al	PROPN
admet-910	62	15	.	.	PUNCT
admet-910	63	1	[	[	X
admet-910	63	2	17	17	NUM
admet-910	63	3	]	]	PUNCT
admet-910	63	4	.	.	PUNCT
admet-910	64	1	they	they	PRON
admet-910	64	2	study	study	VERB
admet-910	64	3	a	a	DET
admet-910	64	4	system	system	NOUN
admet-910	64	5	composed	compose	VERB
admet-910	64	6	of	of	ADP
admet-910	64	7	a	a	DET
admet-910	64	8	lipid	lipid	NOUN
admet-910	64	9	-	-	PUNCT
admet-910	64	10	silica	silica	NOUN
admet-910	64	11	hybrid	hybrid	NOUN
admet-910	64	12	to	to	PART
admet-910	64	13	deliver	deliver	VERB
admet-910	64	14	highly	highly	ADV
admet-910	64	15	lipophilic	lipophilic	ADJ
admet-910	64	16	antipsychotic	antipsychotic	ADJ
admet-910	64	17	compounds	compound	NOUN
admet-910	64	18	.	.	PUNCT
admet-910	65	1	while	while	SCONJ
admet-910	65	2	lurasidone	lurasidone	NOUN
admet-910	65	3	performed	perform	VERB
admet-910	65	4	as	as	SCONJ
admet-910	65	5	expected	expect	VERB
admet-910	65	6	in	in	ADP
admet-910	65	7	this	this	DET
admet-910	65	8	system	system	NOUN
admet-910	65	9	,	,	PUNCT
admet-910	65	10	with	with	ADP
admet-910	65	11	a	a	DET
admet-910	65	12	23	23	NUM
admet-910	65	13	-	-	ADJ
admet-910	65	14	fold	fold	ADJ
admet-910	65	15	increase	increase	NOUN
admet-910	65	16	in	in	ADP
admet-910	65	17	solubilisation	solubilisation	NOUN
admet-910	65	18	being	be	AUX
admet-910	65	19	observed	observe	VERB
admet-910	65	20	for	for	ADP
admet-910	65	21	the	the	DET
admet-910	65	22	developed	develop	VERB
admet-910	65	23	hybrid	hybrid	NOUN
admet-910	65	24	system	system	NOUN
admet-910	65	25	,	,	PUNCT
admet-910	65	26	risperidone	risperidone	NOUN
admet-910	65	27	instead	instead	ADV
admet-910	65	28	showed	show	VERB
admet-910	65	29	a	a	DET
admet-910	65	30	2.2	2.2	NUM
admet-910	65	31	-	-	ADJ
admet-910	65	32	fold	fold	ADJ
admet-910	65	33	reduction	reduction	NOUN
admet-910	65	34	when	when	SCONJ
admet-910	65	35	encapsulated	encapsulate	VERB
admet-910	65	36	in	in	ADP
admet-910	65	37	this	this	DET
admet-910	65	38	hybrid	hybrid	NOUN
admet-910	65	39	.	.	PUNCT
admet-910	66	1	it	it	PRON
admet-910	66	2	was	be	AUX
admet-910	66	3	shown	show	VERB
admet-910	66	4	that	that	SCONJ
admet-910	66	5	differences	difference	NOUN
admet-910	66	6	in	in	ADP
admet-910	66	7	ionization	ionization	NOUN
admet-910	66	8	between	between	ADP
admet-910	66	9	these	these	DET
admet-910	66	10	two	two	NUM
admet-910	66	11	compounds	compound	NOUN
admet-910	66	12	resulted	result	VERB
admet-910	66	13	in	in	ADP
admet-910	66	14	the	the	DET
admet-910	66	15	risperidone	risperidone	NOUN
admet-910	66	16	adsorbed	adsorb	VERB
admet-910	66	17	stronger	strong	ADJ
admet-910	66	18	to	to	ADP
admet-910	66	19	the	the	DET
admet-910	66	20	silica	silica	NOUN
admet-910	66	21	than	than	ADP
admet-910	66	22	the	the	DET
admet-910	66	23	lurasidone	lurasidone	NOUN
admet-910	66	24	,	,	PUNCT
admet-910	66	25	emphasising	emphasise	VERB
admet-910	66	26	the	the	DET
admet-910	66	27	interplay	interplay	NOUN
admet-910	66	28	of	of	ADP
admet-910	66	29	the	the	DET
admet-910	66	30	drug	drug	NOUN
admet-910	66	31	delivery	delivery	NOUN
admet-910	66	32	system	system	NOUN
admet-910	66	33	and	and	CCONJ
admet-910	66	34	the	the	DET
admet-910	66	35	drug	drug	NOUN
admet-910	66	36	itself	itself	PRON
admet-910	66	37	for	for	ADP
admet-910	66	38	optimal	optimal	ADJ
admet-910	66	39	performance	performance	NOUN
admet-910	66	40	.	.	PUNCT
admet-910	67	1	references	reference	NOUN
admet-910	67	2	[	[	X
admet-910	67	3	1	1	X
admet-910	67	4	]	]	PUNCT
admet-910	67	5	c.a.s	c.a.s	PROPN
admet-910	67	6	.	.	PROPN
admet-910	67	7	bergström	bergström	NOUN
admet-910	67	8	,	,	PUNCT
admet-910	67	9	a.	a.	NOUN
admet-910	67	10	avdeef	avdeef	PROPN
admet-910	67	11	.	.	PUNCT
admet-910	68	1	perspectives	perspective	NOUN
admet-910	68	2	in	in	ADP
admet-910	68	3	solubility	solubility	NOUN
admet-910	68	4	measurement	measurement	NOUN
admet-910	68	5	and	and	CCONJ
admet-910	68	6	interpretation	interpretation	NOUN
admet-910	68	7	.	.	PUNCT
admet-910	69	1	admet	admet	PROPN
admet-910	69	2	and	and	CCONJ
admet-910	69	3	dmpk	dmpk	VERB
admet-910	69	4	7	7	NUM
admet-910	69	5	(	(	PUNCT
admet-910	69	6	2019	2019	NUM
admet-910	69	7	)	)	PUNCT
admet-910	69	8	88	88	NUM
admet-910	69	9	-	-	SYM
admet-910	69	10	105	105	NUM
admet-910	69	11	.	.	PUNCT
admet-910	70	1	[	[	X
admet-910	70	2	2	2	NUM
admet-910	70	3	]	]	PUNCT
admet-910	70	4	a.	a.	NOUN
admet-910	70	5	avdeef	avdeef	PROPN
admet-910	70	6	,	,	PUNCT
admet-910	70	7	m.	m.	PROPN
admet-910	70	8	kansy	kansy	PROPN
admet-910	70	9	.	.	PUNCT
admet-910	71	1	can	can	AUX
admet-910	71	2	small	small	ADJ
admet-910	71	3	drugs	drug	NOUN
admet-910	71	4	predict	predict	VERB
admet-910	71	5	the	the	DET
admet-910	71	6	intrinsic	intrinsic	ADJ
admet-910	71	7	aqueous	aqueous	ADJ
admet-910	71	8	solubility	solubility	NOUN
admet-910	71	9	of	of	ADP
admet-910	71	10	‘	'	PUNCT
admet-910	71	11	beyond	beyond	ADP
admet-910	71	12	rule	rule	NOUN
admet-910	71	13	of	of	ADP
admet-910	71	14	5	5	NUM
admet-910	71	15	’	'	PUNCT
admet-910	71	16	big	big	ADJ
admet-910	71	17	drugs	drug	NOUN
admet-910	71	18	?	?	PUNCT
admet-910	71	19	.	.	PUNCT
admet-910	72	1	admet	admet	PROPN
admet-910	72	2	and	and	CCONJ
admet-910	72	3	dmpk	dmpk	VERB
admet-910	72	4	8(3	8(3	NUM
admet-910	72	5	)	)	PUNCT
admet-910	72	6	(	(	PUNCT
admet-910	72	7	2020	2020	NUM
admet-910	72	8	)	)	PUNCT
admet-910	72	9	180	180	NUM
admet-910	72	10	-	-	SYM
admet-910	72	11	206	206	NUM
admet-910	72	12	.	.	PUNCT
admet-910	73	1	[	[	X
admet-910	73	2	3	3	X
admet-910	73	3	]	]	X
admet-910	73	4	g.	g.	NOUN
admet-910	73	5	ermondi	ermondi	PROPN
admet-910	73	6	,	,	PUNCT
admet-910	73	7	v.	v.	ADP
admet-910	73	8	poongavanam	poongavanam	PROPN
admet-910	73	9	,	,	PUNCT
admet-910	73	10	m.	m.	NOUN
admet-910	73	11	vallaro	vallaro	NOUN
admet-910	73	12	,	,	PUNCT
admet-910	73	13	j.	j.	PROPN
admet-910	73	14	kihlberg	kihlberg	PROPN
admet-910	73	15	,	,	PUNCT
admet-910	73	16	g.	g.	PROPN
admet-910	73	17	caron	caron	PROPN
admet-910	73	18	.	.	PUNCT
admet-910	74	1	solubility	solubility	NOUN
admet-910	74	2	prediction	prediction	NOUN
admet-910	74	3	in	in	ADP
admet-910	74	4	the	the	DET
admet-910	74	5	bro5	bro5	NOUN
admet-910	74	6	chemical	chemical	NOUN
admet-910	74	7	space	space	NOUN
admet-910	74	8	:	:	PUNCT
admet-910	74	9	where	where	SCONJ
admet-910	74	10	are	be	AUX
admet-910	74	11	we	we	PRON
admet-910	74	12	right	right	ADV
admet-910	74	13	now	now	ADV
admet-910	74	14	?	?	PUNCT
admet-910	74	15	.	.	PUNCT
admet-910	75	1	admet	admet	PROPN
admet-910	75	2	and	and	CCONJ
admet-910	75	3	dmpk	dmpk	VERB
admet-910	75	4	8(3	8(3	NUM
admet-910	75	5	)	)	PUNCT
admet-910	75	6	(	(	PUNCT
admet-910	75	7	2020	2020	NUM
admet-910	75	8	)	)	PUNCT
admet-910	75	9	207	207	NUM
admet-910	75	10	-	-	SYM
admet-910	75	11	214	214	NUM
admet-910	75	12	.	.	PUNCT
admet-910	76	1	[	[	X
admet-910	76	2	4	4	X
admet-910	76	3	]	]	PUNCT
admet-910	76	4	j.	j.	PROPN
admet-910	76	5	mitchell	mitchell	PROPN
admet-910	76	6	.	.	PUNCT
admet-910	77	1	three	three	NUM
admet-910	77	2	machine	machine	NOUN
admet-910	77	3	learning	learning	NOUN
admet-910	77	4	models	model	NOUN
admet-910	77	5	for	for	ADP
admet-910	77	6	the	the	DET
admet-910	77	7	2019	2019	NUM
admet-910	77	8	solubility	solubility	NOUN
admet-910	77	9	challenge	challenge	NOUN
admet-910	77	10	.	.	PUNCT
admet-910	78	1	admet	admet	PROPN
admet-910	78	2	and	and	CCONJ
admet-910	78	3	dmpk	dmpk	VERB
admet-910	78	4	8(3	8(3	NUM
admet-910	78	5	)	)	PUNCT
admet-910	78	6	(	(	PUNCT
admet-910	78	7	2020	2020	NUM
admet-910	78	8	)	)	PUNCT
admet-910	78	9	215	215	NUM
admet-910	78	10	-	-	SYM
admet-910	78	11	250	250	NUM
admet-910	78	12	.	.	PUNCT
admet-910	79	1	[	[	X
admet-910	79	2	5	5	NUM
admet-910	79	3	]	]	X
admet-910	79	4	g.	g.	PROPN
admet-910	79	5	falcón	falcón	PROPN
admet-910	79	6	-	-	PUNCT
admet-910	79	7	cano	cano	PROPN
admet-910	79	8	,	,	PUNCT
admet-910	79	9	c.	c.	PROPN
admet-910	79	10	molina	molina	PROPN
admet-910	79	11	,	,	PUNCT
admet-910	79	12	m.a	m.a	PROPN
admet-910	79	13	.	.	PROPN
admet-910	79	14	cabrera	cabrera	NOUN
admet-910	79	15	-	-	PUNCT
admet-910	79	16	pérez	pérez	NOUN
admet-910	79	17	.	.	PUNCT
admet-910	80	1	adme	adme	NOUN
admet-910	80	2	prediction	prediction	NOUN
admet-910	80	3	with	with	ADP
admet-910	80	4	knime	knime	NOUN
admet-910	80	5	:	:	PUNCT
admet-910	80	6	in	in	ADP
admet-910	80	7	silico	silico	NOUN
admet-910	80	8	aqueous	aqueous	ADJ
admet-910	80	9	solubility	solubility	NOUN
admet-910	80	10	consensus	consensus	NOUN
admet-910	80	11	model	model	NOUN
admet-910	80	12	based	base	VERB
admet-910	80	13	on	on	ADP
admet-910	80	14	supervised	supervised	ADJ
admet-910	80	15	recursive	recursive	ADJ
admet-910	80	16	random	random	ADJ
admet-910	80	17	forest	forest	NOUN
admet-910	80	18	approaches	approach	NOUN
admet-910	80	19	.	.	PUNCT
admet-910	81	1	admet	admet	PROPN
admet-910	81	2	and	and	CCONJ
admet-910	81	3	dmpk	dmpk	VERB
admet-910	81	4	8(3	8(3	NUM
admet-910	81	5	)	)	PUNCT
admet-910	81	6	(	(	PUNCT
admet-910	81	7	2020	2020	NUM
admet-910	81	8	)	)	PUNCT
admet-910	81	9	251	251	NUM
admet-910	81	10	-	-	SYM
admet-910	81	11	273	273	NUM
admet-910	81	12	.	.	PUNCT
admet-910	82	1	[	[	X
admet-910	82	2	6	6	NUM
admet-910	82	3	]	]	PUNCT
admet-910	82	4	a.	a.	NOUN
admet-910	82	5	mecklenfeld	mecklenfeld	PROPN
admet-910	82	6	,	,	PUNCT
admet-910	82	7	g.	g.	PROPN
admet-910	82	8	raabe	raabe	PROPN
admet-910	82	9	.	.	PUNCT
admet-910	82	10	gaff	gaff	PROPN
admet-910	82	11	/	/	SYM
admet-910	82	12	ipolq	ipolq	NOUN
admet-910	82	13	-	-	PUNCT
admet-910	82	14	mod+lj	mod+lj	NOUN
admet-910	82	15	-	-	NOUN
admet-910	82	16	fit	fit	ADJ
admet-910	82	17	:	:	PUNCT
admet-910	82	18	optimized	optimize	VERB
admet-910	82	19	force	force	NOUN
admet-910	82	20	field	field	NOUN
admet-910	82	21	parameters	parameter	NOUN
admet-910	82	22	for	for	ADP
admet-910	82	23	solvation	solvation	NOUN
admet-910	82	24	free	free	ADJ
admet-910	82	25	energy	energy	NOUN
admet-910	82	26	predictions	prediction	NOUN
admet-910	82	27	.	.	PUNCT
admet-910	83	1	admet	admet	PROPN
admet-910	83	2	and	and	CCONJ
admet-910	83	3	dmpk	dmpk	VERB
admet-910	83	4	8(3	8(3	NUM
admet-910	83	5	)	)	PUNCT
admet-910	83	6	(	(	PUNCT
admet-910	83	7	2020	2020	NUM
admet-910	83	8	)	)	PUNCT
admet-910	83	9	274	274	NUM
admet-910	83	10	-	-	SYM
admet-910	83	11	296	296	NUM
admet-910	83	12	.	.	PUNCT
admet-910	84	1	[	[	X
admet-910	84	2	7	7	X
admet-910	84	3	]	]	PUNCT
admet-910	84	4	m.	m.	NOUN
admet-910	84	5	abrami	abrami	PROPN
admet-910	84	6	,	,	PUNCT
admet-910	84	7	l.	l.	PROPN
admet-910	84	8	grassi	grassi	PROPN
admet-910	84	9	,	,	PUNCT
admet-910	84	10	r.	r.	PROPN
admet-910	84	11	di	di	PROPN
admet-910	84	12	vittorio	vittorio	PROPN
admet-910	84	13	,	,	PUNCT
admet-910	84	14	d.	d.	PROPN
admet-910	84	15	hasa	hasa	PROPN
admet-910	84	16	,	,	PUNCT
admet-910	84	17	b.	b.	PROPN
admet-910	84	18	perissutti	perissutti	PROPN
admet-910	84	19	,	,	PUNCT
admet-910	84	20	d.	d.	PROPN
admet-910	84	21	voinovich	voinovich	PROPN
admet-910	84	22	,	,	PUNCT
admet-910	84	23	g.	g.	PROPN
admet-910	84	24	grassi	grassi	PROPN
admet-910	84	25	,	,	PUNCT
admet-910	84	26	i.	i.	PROPN
admet-910	84	27	colombo	colombo	PROPN
admet-910	84	28	,	,	PUNCT
admet-910	84	29	m.	m.	NOUN
admet-910	84	30	grassi	grassi	PROPN
admet-910	84	31	.	.	PUNCT
admet-910	85	1	dissolution	dissolution	NOUN
admet-910	85	2	of	of	ADP
admet-910	85	3	an	an	DET
admet-910	85	4	ensemble	ensemble	NOUN
admet-910	85	5	of	of	ADP
admet-910	85	6	differently	differently	ADV
admet-910	85	7	shaped	shape	VERB
admet-910	85	8	poly	poly	ADJ
admet-910	85	9	-	-	PUNCT
admet-910	85	10	dispersed	disperse	VERB
admet-910	85	11	drug	drug	NOUN
admet-910	85	12	particles	particle	NOUN
admet-910	85	13	undergoing	undergo	VERB
admet-910	85	14	solubility	solubility	NOUN
admet-910	85	15	reduction	reduction	NOUN
admet-910	85	16	:	:	PUNCT
admet-910	85	17	mathematical	mathematical	ADJ
admet-910	85	18	modelling	modelling	NOUN
admet-910	85	19	.	.	PUNCT
admet-910	86	1	admet	admet	PROPN
admet-910	86	2	and	and	CCONJ
admet-910	86	3	dmpk	dmpk	VERB
admet-910	86	4	8(3	8(3	NUM
admet-910	86	5	)	)	PUNCT
admet-910	86	6	(	(	PUNCT
admet-910	86	7	2020	2020	NUM
admet-910	86	8	)	)	PUNCT
admet-910	86	9	297	297	NUM
admet-910	86	10	-	-	SYM
admet-910	86	11	313	313	NUM
admet-910	86	12	.	.	PUNCT
admet-910	87	1	[	[	X
admet-910	87	2	8	8	NUM
admet-910	87	3	]	]	X
admet-910	87	4	k.c	k.c	PROPN
admet-910	87	5	.	.	PROPN
admet-910	87	6	johnson	johnson	PROPN
admet-910	87	7	.	.	PUNCT
admet-910	88	1	mechanistic	mechanistic	ADJ
admet-910	88	2	modeling	modeling	NOUN
admet-910	88	3	of	of	ADP
admet-910	88	4	gastrointestinal	gastrointestinal	ADJ
admet-910	88	5	motility	motility	NOUN
admet-910	88	6	with	with	ADP
admet-910	88	7	integrated	integrate	VERB
admet-910	88	8	dissolution	dissolution	NOUN
admet-910	88	9	for	for	ADP
admet-910	88	10	simulating	simulate	VERB
admet-910	88	11	drug	drug	NOUN
admet-910	88	12	absorption	absorption	NOUN
admet-910	88	13	.	.	PUNCT
admet-910	89	1	admet	admet	PROPN
admet-910	89	2	and	and	CCONJ
admet-910	89	3	dmpk	dmpk	VERB
admet-910	89	4	8(3	8(3	NUM
admet-910	89	5	)	)	PUNCT
admet-910	89	6	(	(	PUNCT
admet-910	89	7	2020	2020	NUM
admet-910	89	8	)	)	PUNCT
admet-910	89	9	314	314	NUM
admet-910	89	10	-	-	SYM
admet-910	89	11	324	324	NUM
admet-910	89	12	.	.	PUNCT
admet-910	90	1	[	[	X
admet-910	90	2	9	9	NUM
admet-910	90	3	]	]	PUNCT
admet-910	90	4	l.	l.	PROPN
admet-910	90	5	castillo	castillo	PROPN
admet-910	90	6	-	-	PUNCT
admet-910	90	7	henríquez	henríquez	PROPN
admet-910	90	8	,	,	PUNCT
admet-910	90	9	r.	r.	PROPN
admet-910	90	10	vargas	vargas	PROPN
admet-910	90	11	-	-	PUNCT
admet-910	90	12	zúñiga	zúñiga	PROPN
admet-910	90	13	,	,	PUNCT
admet-910	90	14	j.	j.	PROPN
admet-910	90	15	pacheco	pacheco	PROPN
admet-910	90	16	-	-	PUNCT
admet-910	90	17	molina	molina	PROPN
admet-910	90	18	,	,	PUNCT
admet-910	90	19	j.	j.	PROPN
admet-910	90	20	vega	vega	PROPN
admet-910	90	21	-	-	PUNCT
admet-910	90	22	baudrit	baudrit	PROPN
admet-910	90	23	.	.	PUNCT
admet-910	91	1	electrospun	electrospun	PROPN
admet-910	91	2	nanofibers	nanofiber	VERB
admet-910	91	3	:	:	PUNCT
admet-910	91	4	a	a	DET
admet-910	91	5	nanotechnological	nanotechnological	ADJ
admet-910	91	6	approach	approach	NOUN
admet-910	91	7	for	for	ADP
admet-910	91	8	drug	drug	NOUN
admet-910	91	9	delivery	delivery	NOUN
admet-910	91	10	and	and	CCONJ
admet-910	91	11	dissolution	dissolution	ADJ
admet-910	91	12	optimization	optimization	NOUN
admet-910	91	13	in	in	ADP
admet-910	91	14	poorly	poorly	ADV
admet-910	91	15	water	water	NOUN
admet-910	91	16	-	-	PUNCT
admet-910	91	17	soluble	soluble	ADJ
admet-910	91	18	drugs	drug	NOUN
admet-910	91	19	.	.	PUNCT
admet-910	92	1	admet	admet	PROPN
admet-910	92	2	and	and	CCONJ
admet-910	92	3	dmpk	dmpk	NOUN
admet-910	92	4	8(4	8(4	NOUN
admet-910	92	5	)	)	PUNCT
admet-910	92	6	(	(	PUNCT
admet-910	92	7	2020	2020	NUM
admet-910	92	8	)	)	PUNCT
admet-910	92	9	325	325	NUM
admet-910	92	10	-	-	SYM
admet-910	92	11	353	353	NUM
admet-910	92	12	.	.	PUNCT
admet-910	93	1	[	[	X
admet-910	93	2	10	10	NUM
admet-910	93	3	]	]	X
admet-910	93	4	s.k	s.k	PROPN
admet-910	93	5	.	.	PROPN
admet-910	93	6	misra	misra	PROPN
admet-910	93	7	,	,	PUNCT
admet-910	93	8	k.	k.	PROPN
admet-910	93	9	pathak	pathak	PROPN
admet-910	93	10	.	.	PUNCT
admet-910	94	1	supercritical	supercritical	ADJ
admet-910	94	2	fluid	fluid	ADJ
admet-910	94	3	technology	technology	NOUN
admet-910	94	4	for	for	ADP
admet-910	94	5	solubilization	solubilization	NOUN
admet-910	94	6	of	of	ADP
admet-910	94	7	poorly	poorly	ADV
admet-910	94	8	water	water	NOUN
admet-910	94	9	soluble	soluble	ADJ
admet-910	94	10	drugs	drug	NOUN
admet-910	94	11	via	via	ADP
admet-910	94	12	microand	microand	NOUN
admet-910	94	13	naonosized	naonosize	VERB
admet-910	94	14	particle	particle	NOUN
admet-910	94	15	generation	generation	NOUN
admet-910	94	16	.	.	PUNCT
admet-910	95	1	admet	admet	PROPN
admet-910	95	2	and	and	CCONJ
admet-910	95	3	dmpk	dmpk	NOUN
admet-910	95	4	8(4	8(4	NOUN
admet-910	95	5	)	)	PUNCT
admet-910	95	6	(	(	PUNCT
admet-910	95	7	2020	2020	NUM
admet-910	95	8	)	)	PUNCT
admet-910	95	9	355	355	NUM
admet-910	95	10	-	-	SYM
admet-910	95	11	374	374	NUM
admet-910	95	12	.	.	PUNCT
admet-910	96	1	[	[	X
admet-910	96	2	11	11	NUM
admet-910	96	3	]	]	X
admet-910	96	4	d.	d.	PROPN
admet-910	96	5	dahlgren	dahlgren	PROPN
admet-910	96	6	,	,	PUNCT
admet-910	96	7	e.	e.	PROPN
admet-910	96	8	sjögren	sjögren	PROPN
admet-910	96	9	,	,	PUNCT
admet-910	96	10	h.	h.	PROPN
admet-910	96	11	lennernäs	lennernäs	PROPN
admet-910	96	12	.	.	PUNCT
admet-910	97	1	intestinal	intestinal	ADJ
admet-910	97	2	absorption	absorption	NOUN
admet-910	97	3	of	of	ADP
admet-910	97	4	bcs	bcs	NOUN
admet-910	97	5	class	class	NOUN
admet-910	97	6	ii	ii	NOUN
admet-910	97	7	drugs	drug	NOUN
admet-910	97	8	administered	administer	VERB
admet-910	97	9	as	as	ADP
admet-910	97	10	nanoparticles	nanoparticle	NOUN
admet-910	97	11	:	:	PUNCT
admet-910	97	12	a	a	DET
admet-910	97	13	review	review	NOUN
admet-910	97	14	based	base	VERB
admet-910	97	15	on	on	ADP
admet-910	97	16	in	in	ADP
admet-910	97	17	vivo	vivo	ADJ
admet-910	97	18	data	datum	NOUN
admet-910	97	19	from	from	ADP
admet-910	97	20	intestinal	intestinal	ADJ
admet-910	97	21	perfusion	perfusion	NOUN
admet-910	97	22	models	model	NOUN
admet-910	97	23	.	.	PUNCT
admet-910	98	1	admet	admet	PROPN
admet-910	98	2	and	and	CCONJ
admet-910	98	3	dmpk	dmpk	NOUN
admet-910	98	4	8(4	8(4	NOUN
admet-910	98	5	)	)	PUNCT
admet-910	98	6	(	(	PUNCT
admet-910	98	7	2020	2020	NUM
admet-910	98	8	)	)	PUNCT
admet-910	98	9	375	375	NUM
admet-910	98	10	-	-	SYM
admet-910	98	11	390	390	NUM
admet-910	98	12	.	.	PUNCT
admet-910	99	1	admet	admet	PROPN
admet-910	99	2	&	&	CCONJ
admet-910	99	3	dmpk	dmpk	PROPN
admet-910	99	4	8(3	8(3	NUM
admet-910	99	5	)	)	PUNCT
admet-910	99	6	(	(	PUNCT
admet-910	99	7	2020	2020	NUM
admet-910	99	8	)	)	PUNCT
admet-910	99	9	176	176	NUM
admet-910	99	10	-	-	SYM
admet-910	99	11	179	179	NUM
admet-910	99	12	editorial	editorial	NOUN
admet-910	99	13	,	,	PUNCT
admet-910	99	14	solubility	solubility	NOUN
admet-910	99	15	issue	issue	NOUN
admet-910	99	16	doi	doi	PROPN
admet-910	99	17	:	:	PUNCT
admet-910	99	18	https://doi.org/10.5599/admet.910	https://doi.org/10.5599/admet.910	NOUN
admet-910	99	19	179	179	NUM
admet-910	100	1	[	[	X
admet-910	100	2	12	12	NUM
admet-910	100	3	]	]	PUNCT
admet-910	100	4	m.	m.	NOUN
admet-910	100	5	vihinen	vihinen	PROPN
admet-910	100	6	.	.	PUNCT
admet-910	101	1	solubility	solubility	NOUN
admet-910	101	2	of	of	ADP
admet-910	101	3	proteins	protein	NOUN
admet-910	101	4	.	.	PUNCT
admet-910	102	1	admet	admet	PROPN
admet-910	102	2	and	and	CCONJ
admet-910	102	3	dmpk	dmpk	NOUN
admet-910	102	4	8(4	8(4	NOUN
admet-910	102	5	)	)	PUNCT
admet-910	102	6	(	(	PUNCT
admet-910	102	7	2020	2020	NUM
admet-910	102	8	)	)	PUNCT
admet-910	102	9	391	391	NUM
admet-910	102	10	-	-	SYM
admet-910	102	11	399	399	NUM
admet-910	102	12	.	.	PUNCT
admet-910	103	1	[	[	X
admet-910	103	2	13	13	NUM
admet-910	103	3	]	]	PUNCT
admet-910	103	4	j.	j.	PROPN
admet-910	103	5	štukelj	štukelj	PROPN
admet-910	103	6	,	,	PUNCT
admet-910	103	7	m.	m.	NOUN
admet-910	103	8	agopov	agopov	PROPN
admet-910	103	9	,	,	PUNCT
admet-910	103	10	j.	j.	PROPN
admet-910	103	11	yliruusi	yliruusi	PROPN
admet-910	103	12	,	,	PUNCT
admet-910	103	13	c.j	c.j	PROPN
admet-910	103	14	.	.	PROPN
admet-910	103	15	strachan	strachan	PROPN
admet-910	103	16	,	,	PUNCT
admet-910	103	17	s.	s.	PROPN
admet-910	103	18	svanbäck	svanbäck	PROPN
admet-910	103	19	.	.	PUNCT
admet-910	103	20	image	image	NOUN
admet-910	103	21	-	-	PUNCT
admet-910	103	22	based	base	VERB
admet-910	103	23	dissolution	dissolution	ADJ
admet-910	103	24	analysis	analysis	NOUN
admet-910	103	25	for	for	ADP
admet-910	103	26	tracking	track	VERB
admet-910	103	27	the	the	DET
admet-910	103	28	surface	surface	NOUN
admet-910	103	29	stability	stability	NOUN
admet-910	103	30	of	of	ADP
admet-910	103	31	amorphous	amorphous	ADJ
admet-910	103	32	powders	powder	NOUN
admet-910	103	33	.	.	PUNCT
admet-910	104	1	admet	admet	PROPN
admet-910	104	2	and	and	CCONJ
admet-910	104	3	dmpk	dmpk	NOUN
admet-910	104	4	8(4	8(4	NOUN
admet-910	104	5	)	)	PUNCT
admet-910	104	6	(	(	PUNCT
admet-910	104	7	2020	2020	NUM
admet-910	104	8	)	)	PUNCT
admet-910	104	9	401	401	NUM
admet-910	104	10	-	-	SYM
admet-910	104	11	409	409	NUM
admet-910	104	12	.	.	PUNCT
admet-910	105	1	[	[	X
admet-910	105	2	14	14	NUM
admet-910	105	3	]	]	X
admet-910	105	4	v.	v.	X
admet-910	105	5	gigante	gigante	PROPN
admet-910	105	6	,	,	PUNCT
admet-910	105	7	g.m	g.m	PROPN
admet-910	105	8	.	.	PROPN
admet-910	105	9	pauletti	pauletti	PROPN
admet-910	105	10	,	,	PUNCT
admet-910	105	11	s.	s.	PROPN
admet-910	105	12	kopp	kopp	PROPN
admet-910	105	13	,	,	PUNCT
admet-910	105	14	m.	m.	PROPN
admet-910	105	15	xu	xu	PROPN
admet-910	105	16	,	,	PUNCT
admet-910	105	17	i.	i.	PROPN
admet-910	105	18	gonzalez	gonzalez	PROPN
admet-910	105	19	-	-	PUNCT
admet-910	105	20	alvarez	alvarez	PROPN
admet-910	105	21	,	,	PUNCT
admet-910	105	22	v.	v.	ADP
admet-910	105	23	merino	merino	NOUN
admet-910	105	24	,	,	PUNCT
admet-910	105	25	m.p	m.p	PROPN
admet-910	105	26	.	.	PROPN
admet-910	105	27	mcintosh	mcintosh	PROPN
admet-910	105	28	,	,	PUNCT
admet-910	105	29	a.	a.	PROPN
admet-910	105	30	wessels	wessels	PROPN
admet-910	105	31	,	,	PUNCT
admet-910	105	32	b.-j	b.-j	PROPN
admet-910	105	33	.	.	PUNCT
admet-910	106	1	lee	lee	PROPN
admet-910	106	2	,	,	PUNCT
admet-910	106	3	k.r	k.r	PROPN
admet-910	106	4	.	.	PROPN
admet-910	106	5	rezende	rezende	PROPN
admet-910	106	6	,	,	PUNCT
admet-910	106	7	g.k.e	g.k.e	NOUN
admet-910	106	8	.	.	PUNCT
admet-910	106	9	scriba	scriba	PROPN
admet-910	106	10	,	,	PUNCT
admet-910	106	11	g.p.s	g.p.s	PROPN
admet-910	106	12	.	.	PUNCT
admet-910	106	13	jadaun	jadaun	PROPN
admet-910	106	14	,	,	PUNCT
admet-910	106	15	m.	m.	NOUN
admet-910	106	16	bermejo	bermejo	PROPN
admet-910	106	17	.	.	PUNCT
admet-910	107	1	admet	admet	PROPN
admet-910	107	2	and	and	CCONJ
admet-910	107	3	dmpk	dmpk	PROPN
admet-910	107	4	doi	doi	PROPN
admet-910	107	5	:	:	PUNCT
admet-910	107	6	https://doi.org/10.5599/admet.850	https://doi.org/10.5599/admet.850	PROPN
admet-910	107	7	.	.	PUNCT
admet-910	108	1	[	[	X
admet-910	108	2	15	15	NUM
admet-910	108	3	]	]	X
admet-910	108	4	r.	r.	PROPN
admet-910	108	5	medina	medina	PROPN
admet-910	108	6	-	-	PUNCT
admet-910	108	7	lópez	lópez	PROPN
admet-910	108	8	,	,	PUNCT
admet-910	108	9	s.	s.	PROPN
admet-910	108	10	guillén	guillén	PROPN
admet-910	108	11	-	-	PUNCT
admet-910	108	12	moedano	moedano	ADJ
admet-910	108	13	,	,	PUNCT
admet-910	108	14	m.	m.	NOUN
admet-910	108	15	hurtado	hurtado	NOUN
admet-910	108	16	.	.	PUNCT
admet-910	109	1	in	in	ADP
admet-910	109	2	vitro	vitro	X
admet-910	109	3	release	release	NOUN
admet-910	109	4	studies	study	NOUN
admet-910	109	5	of	of	ADP
admet-910	109	6	furosemide	furosemide	ADJ
admet-910	109	7	reference	reference	NOUN
admet-910	109	8	tablets	tablet	NOUN
admet-910	109	9	:	:	PUNCT
admet-910	109	10	influence	influence	NOUN
admet-910	109	11	of	of	ADP
admet-910	109	12	agitation	agitation	NOUN
admet-910	109	13	rate	rate	NOUN
admet-910	109	14	,	,	PUNCT
admet-910	109	15	usp	usp	NOUN
admet-910	109	16	apparatus	apparatus	NOUN
admet-910	109	17	and	and	CCONJ
admet-910	109	18	dissolution	dissolution	ADJ
admet-910	109	19	media	medium	NOUN
admet-910	109	20	.	.	PUNCT
admet-910	110	1	admet	admet	PROPN
admet-910	110	2	and	and	CCONJ
admet-910	110	3	dmpk	dmpk	NOUN
admet-910	110	4	8(4	8(4	NOUN
admet-910	110	5	)	)	PUNCT
admet-910	110	6	(	(	PUNCT
admet-910	110	7	2020	2020	NUM
admet-910	110	8	)	)	PUNCT
admet-910	110	9	411	411	NUM
admet-910	110	10	-	-	SYM
admet-910	110	11	423	423	NUM
admet-910	110	12	.	.	PUNCT
admet-910	111	1	[	[	X
admet-910	111	2	16	16	NUM
admet-910	111	3	]	]	X
admet-910	111	4	d.	d.	PROPN
admet-910	111	5	dascălu	dascălu	PROPN
admet-910	111	6	,	,	PUNCT
admet-910	111	7	d.l	d.l	PROPN
admet-910	111	8	.	.	PROPN
admet-910	111	9	roman	roman	PROPN
admet-910	111	10	,	,	PUNCT
admet-910	111	11	m.	m.	NOUN
admet-910	111	12	filip	filip	PROPN
admet-910	111	13	,	,	PUNCT
admet-910	111	14	a.a	a.a	PROPN
admet-910	111	15	.	.	PROPN
admet-910	111	16	ciorsac	ciorsac	PROPN
admet-910	111	17	,	,	PUNCT
admet-910	111	18	v.	v.	ADP
admet-910	111	19	ostafe	ostafe	NOUN
admet-910	111	20	,	,	PUNCT
admet-910	111	21	a.	a.	NOUN
admet-910	111	22	isvoran	isvoran	NOUN
admet-910	111	23	.	.	PUNCT
admet-910	112	1	solubility	solubility	NOUN
admet-910	112	2	and	and	CCONJ
admet-910	112	3	admet	admet	PROPN
admet-910	112	4	profiles	profile	NOUN
admet-910	112	5	of	of	ADP
admet-910	112	6	short	short	ADJ
admet-910	112	7	oligomers	oligomer	NOUN
admet-910	112	8	of	of	ADP
admet-910	112	9	lactic	lactic	ADJ
admet-910	112	10	acid	acid	NOUN
admet-910	112	11	.	.	PUNCT
admet-910	113	1	admet	admet	PROPN
admet-910	113	2	and	and	CCONJ
admet-910	113	3	dmpk	dmpk	NOUN
admet-910	113	4	8(4	8(4	NOUN
admet-910	113	5	)	)	PUNCT
admet-910	113	6	(	(	PUNCT
admet-910	113	7	2020	2020	NUM
admet-910	113	8	)	)	PUNCT
admet-910	113	9	425	425	NUM
admet-910	113	10	-	-	SYM
admet-910	113	11	436	436	NUM
admet-910	113	12	.	.	PUNCT
admet-910	114	1	[	[	X
admet-910	114	2	17	17	NUM
admet-910	114	3	]	]	X
admet-910	114	4	t.r	t.r	PROPN
admet-910	114	5	.	.	PROPN
admet-910	114	6	meola	meola	PROPN
admet-910	114	7	,	,	PUNCT
admet-910	114	8	k.	k.	PROPN
admet-910	114	9	paxton	paxton	PROPN
admet-910	114	10	,	,	PUNCT
admet-910	114	11	p.	p.	PROPN
admet-910	114	12	joyce	joyce	PROPN
admet-910	114	13	,	,	PUNCT
admet-910	114	14	h.b	h.b	PROPN
admet-910	114	15	.	.	PROPN
admet-910	114	16	schultz	schultz	PROPN
admet-910	114	17	,	,	PUNCT
admet-910	114	18	c.a	c.a	PROPN
admet-910	114	19	.	.	PROPN
admet-910	114	20	prestidge	prestidge	PROPN
admet-910	114	21	.	.	PUNCT
admet-910	115	1	the	the	DET
admet-910	115	2	effect	effect	NOUN
admet-910	115	3	of	of	ADP
admet-910	115	4	drug	drug	NOUN
admet-910	115	5	ionization	ionization	NOUN
admet-910	115	6	on	on	ADP
admet-910	115	7	lipidbased	lipidbased	ADJ
admet-910	115	8	formulations	formulation	NOUN
admet-910	115	9	for	for	ADP
admet-910	115	10	the	the	DET
admet-910	115	11	oral	oral	ADJ
admet-910	115	12	delivery	delivery	NOUN
admet-910	115	13	of	of	ADP
admet-910	115	14	anti	anti	NOUN
admet-910	115	15	-	-	NOUN
admet-910	115	16	psychotics	psychotic	NOUN
admet-910	115	17	.	.	PUNCT
admet-910	116	1	admet	admet	PROPN
admet-910	116	2	and	and	CCONJ
admet-910	116	3	dmpk	dmpk	NOUN
admet-910	116	4	8(4	8(4	NOUN
admet-910	116	5	)	)	PUNCT
admet-910	116	6	(	(	PUNCT
admet-910	116	7	2020	2020	NUM
admet-910	116	8	)	)	PUNCT
admet-910	116	9	437	437	NUM
admet-910	116	10	-	-	SYM
admet-910	116	11	451	451	NUM
admet-910	116	12	.	.	PUNCT
admet-910	117	1	©	©	PROPN
admet-910	117	2	2020	2020	NUM
admet-910	117	3	by	by	ADP
admet-910	117	4	the	the	DET
admet-910	117	5	authors	author	NOUN
admet-910	117	6	;	;	PUNCT
admet-910	117	7	licensee	licensee	PROPN
admet-910	117	8	iapc	iapc	PROPN
admet-910	117	9	,	,	PUNCT
admet-910	117	10	zagreb	zagreb	PROPN
admet-910	117	11	,	,	PUNCT
admet-910	117	12	croatia	croatia	PROPN
admet-910	117	13	.	.	PUNCT
admet-910	118	1	this	this	DET
admet-910	118	2	article	article	NOUN
admet-910	118	3	is	be	AUX
admet-910	118	4	an	an	DET
admet-910	118	5	open	open	ADJ
admet-910	118	6	-	-	PUNCT
admet-910	118	7	access	access	NOUN
admet-910	118	8	article	article	NOUN
admet-910	118	9	distributed	distribute	VERB
admet-910	118	10	under	under	ADP
admet-910	118	11	the	the	DET
admet-910	118	12	terms	term	NOUN
admet-910	118	13	and	and	CCONJ
admet-910	118	14	conditions	condition	NOUN
admet-910	118	15	of	of	ADP
admet-910	118	16	the	the	DET
admet-910	118	17	creative	creative	ADJ
admet-910	118	18	commons	common	NOUN
admet-910	118	19	attribution	attribution	NOUN
admet-910	118	20	license	license	NOUN
admet-910	118	21	(	(	PUNCT
admet-910	118	22	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN
admet-910	118	23	)	)	PUNCT
admet-910	118	24	https://doi.org/10.5599/admet.910	https://doi.org/10.5599/admet.910	NOUN
admet-910	118	25	https://doi.org/10.5599/admet.850	https://doi.org/10.5599/admet.850	ADV
admet-910	118	26	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN