id	sid	tid	token	lemma	pos
admet-942	1	1	organ	organ	VERB
admet-942	1	2	-	-	PUNCT
admet-942	1	3	on	on	ADP
admet-942	1	4	-	-	PUNCT
admet-942	1	5	a	a	DET
admet-942	1	6	-	-	PUNCT
admet-942	1	7	chip	chip	NOUN
admet-942	1	8	systems	system	NOUN
admet-942	1	9	for	for	ADP
admet-942	1	10	new	new	ADJ
admet-942	1	11	drugs	drug	NOUN
admet-942	1	12	development	development	NOUN
admet-942	1	13	doi	doi	PROPN
admet-942	1	14	:	:	PUNCT
admet-942	1	15	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	NOUN
admet-942	1	16	111	111	NUM
admet-942	1	17	admet	admet	X
admet-942	1	18	&	&	CCONJ
admet-942	1	19	dmpk	dmpk	PROPN
admet-942	1	20	9(2	9(2	NUM
admet-942	1	21	)	)	PUNCT
admet-942	1	22	(	(	PUNCT
admet-942	1	23	2021	2021	NUM
admet-942	1	24	)	)	PUNCT
admet-942	1	25	111	111	NUM
admet-942	1	26	-	-	SYM
admet-942	1	27	141	141	NUM
admet-942	1	28	;	;	PUNCT
admet-942	1	29	doi	doi	NOUN
admet-942	1	30	:	:	PUNCT
admet-942	1	31	http://dx.doi.org/10.5599/admet.942	http://dx.doi.org/10.5599/admet.942	ADJ
admet-942	1	32	open	open	ADJ
admet-942	1	33	access	access	NOUN
admet-942	1	34	:	:	PUNCT
admet-942	1	35	issn	issn	PROPN
admet-942	1	36	:	:	PUNCT
admet-942	1	37	1848	1848	NUM
admet-942	1	38	-	-	SYM
admet-942	1	39	7718	7718	NUM
admet-942	1	40	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	NOUN
admet-942	1	41	review	review	NOUN
admet-942	1	42	organ	organ	NOUN
admet-942	1	43	-	-	PUNCT
admet-942	1	44	on	on	ADP
admet-942	1	45	-	-	PUNCT
admet-942	1	46	a	a	DET
admet-942	1	47	-	-	PUNCT
admet-942	1	48	chip	chip	NOUN
admet-942	1	49	systems	system	NOUN
admet-942	1	50	for	for	ADP
admet-942	1	51	new	new	ADJ
admet-942	1	52	drugs	drug	NOUN
admet-942	1	53	development	development	PROPN
admet-942	1	54	ronny	ronny	PROPN
admet-942	1	55	vargas1,2	vargas1,2	PROPN
admet-942	1	56	*	*	PROPN
admet-942	1	57	,	,	PUNCT
admet-942	1	58	andrea	andrea	PROPN
admet-942	1	59	egurbide	egurbide	NOUN
admet-942	1	60	-	-	PUNCT
admet-942	1	61	sifre2	sifre2	NOUN
admet-942	1	62	and	and	CCONJ
admet-942	1	63	laura	laura	PROPN
admet-942	1	64	medina2	medina2	NOUN
admet-942	1	65	1	1	NUM
admet-942	1	66	industrial	industrial	ADJ
admet-942	1	67	pharmacy	pharmacy	NOUN
admet-942	1	68	department	department	NOUN
admet-942	1	69	,	,	PUNCT
admet-942	1	70	faculty	faculty	NOUN
admet-942	1	71	of	of	ADP
admet-942	1	72	pharmacy	pharmacy	NOUN
admet-942	1	73	,	,	PUNCT
admet-942	1	74	university	university	PROPN
admet-942	1	75	of	of	ADP
admet-942	1	76	costa	costa	PROPN
admet-942	1	77	rica	rica	PROPN
admet-942	1	78	11501	11501	NUM
admet-942	1	79	-	-	SYM
admet-942	1	80	2060	2060	NUM
admet-942	1	81	,	,	PUNCT
admet-942	1	82	san	san	PROPN
admet-942	1	83	josé	josé	PROPN
admet-942	1	84	,	,	PUNCT
admet-942	1	85	costa	costa	PROPN
admet-942	1	86	rica	rica	PROPN
admet-942	1	87	2	2	NUM
admet-942	1	88	faculty	faculty	NOUN
admet-942	1	89	of	of	ADP
admet-942	1	90	pharmacy	pharmacy	NOUN
admet-942	1	91	and	and	CCONJ
admet-942	1	92	food	food	NOUN
admet-942	1	93	sciences	science	NOUN
admet-942	1	94	,	,	PUNCT
admet-942	1	95	university	university	PROPN
admet-942	1	96	of	of	ADP
admet-942	1	97	barcelona	barcelona	PROPN
admet-942	1	98	,	,	PUNCT
admet-942	1	99	av	av	PROPN
admet-942	1	100	.	.	PUNCT
admet-942	1	101	joan	joan	PROPN
admet-942	1	102	xxiii	xxiii	PROPN
admet-942	1	103	,	,	PUNCT
admet-942	1	104	27	27	NUM
admet-942	1	105	-	-	SYM
admet-942	1	106	1	1	NUM
admet-942	1	107	,	,	PUNCT
admet-942	1	108	08028	08028	NUM
admet-942	1	109	,	,	PUNCT
admet-942	1	110	barcelona	barcelona	PROPN
admet-942	1	111	,	,	PUNCT
admet-942	1	112	spain	spain	PROPN
admet-942	1	113	.	.	PUNCT
admet-942	2	1	*	*	PUNCT
admet-942	2	2	corresponding	correspond	VERB
admet-942	2	3	author	author	NOUN
admet-942	2	4	:	:	PUNCT
admet-942	2	5	e	e	NOUN
admet-942	2	6	-	-	NOUN
admet-942	2	7	mail	mail	NOUN
admet-942	2	8	:	:	PUNCT
admet-942	2	9	ronny.vargas_m@ucr.ac.cr	ronny.vargas_m@ucr.ac.cr	ADJ
admet-942	2	10	;	;	PUNCT
admet-942	2	11	tel	tel	PROPN
admet-942	2	12	.	.	PUNCT
admet-942	2	13	:	:	PUNCT
admet-942	3	1	+34	+34	ADJ
admet-942	3	2	-	-	PUNCT
admet-942	3	3	665	665	NUM
admet-942	3	4	-	-	PUNCT
admet-942	3	5	873	873	NUM
admet-942	3	6	-	-	PUNCT
admet-942	3	7	028	028	NUM
admet-942	3	8	received	receive	VERB
admet-942	3	9	:	:	PUNCT
admet-942	3	10	december	december	PROPN
admet-942	3	11	22	22	NUM
admet-942	3	12	,	,	PUNCT
admet-942	3	13	2020	2020	NUM
admet-942	3	14	;	;	PUNCT
admet-942	3	15	revised	revise	VERB
admet-942	3	16	:	:	PUNCT
admet-942	3	17	march	march	PROPN
admet-942	3	18	04	04	NUM
admet-942	3	19	,	,	PUNCT
admet-942	3	20	2021	2021	NUM
admet-942	3	21	;	;	PUNCT
admet-942	3	22	published	publish	VERB
admet-942	3	23	online	online	ADV
admet-942	3	24	:	:	PUNCT
admet-942	3	25	march	march	PROPN
admet-942	3	26	22	22	NUM
admet-942	3	27	,	,	PUNCT
admet-942	3	28	2021	2021	NUM
admet-942	3	29	abstract	abstract	ADJ
admet-942	3	30	research	research	NOUN
admet-942	3	31	on	on	ADP
admet-942	3	32	alternatives	alternative	NOUN
admet-942	3	33	to	to	ADP
admet-942	3	34	the	the	DET
admet-942	3	35	use	use	NOUN
admet-942	3	36	of	of	ADP
admet-942	3	37	animal	animal	NOUN
admet-942	3	38	models	model	NOUN
admet-942	3	39	and	and	CCONJ
admet-942	3	40	cell	cell	NOUN
admet-942	3	41	cultures	culture	NOUN
admet-942	3	42	has	have	AUX
admet-942	3	43	led	lead	VERB
admet-942	3	44	to	to	ADP
admet-942	3	45	the	the	DET
admet-942	3	46	creation	creation	NOUN
admet-942	3	47	of	of	ADP
admet-942	3	48	organ	organ	NOUN
admet-942	3	49	-	-	PUNCT
admet-942	3	50	ona	ona	NOUN
admet-942	3	51	-	-	PUNCT
admet-942	3	52	chip	chip	NOUN
admet-942	3	53	systems	system	NOUN
admet-942	3	54	,	,	PUNCT
admet-942	3	55	in	in	ADP
admet-942	3	56	which	which	PRON
admet-942	3	57	organs	organ	NOUN
admet-942	3	58	and	and	CCONJ
admet-942	3	59	their	their	PRON
admet-942	3	60	physiological	physiological	ADJ
admet-942	3	61	reactions	reaction	NOUN
admet-942	3	62	to	to	ADP
admet-942	3	63	the	the	DET
admet-942	3	64	presence	presence	NOUN
admet-942	3	65	of	of	ADP
admet-942	3	66	external	external	ADJ
admet-942	3	67	stimuli	stimulus	NOUN
admet-942	3	68	are	be	AUX
admet-942	3	69	simulated	simulate	VERB
admet-942	3	70	.	.	PUNCT
admet-942	4	1	these	these	DET
admet-942	4	2	systems	system	NOUN
admet-942	4	3	could	could	AUX
admet-942	4	4	even	even	ADV
admet-942	4	5	replace	replace	VERB
admet-942	4	6	the	the	DET
admet-942	4	7	use	use	NOUN
admet-942	4	8	of	of	ADP
admet-942	4	9	human	human	ADJ
admet-942	4	10	beings	being	NOUN
admet-942	4	11	as	as	ADP
admet-942	4	12	subjects	subject	NOUN
admet-942	4	13	for	for	ADP
admet-942	4	14	the	the	DET
admet-942	4	15	study	study	NOUN
admet-942	4	16	of	of	ADP
admet-942	4	17	drugs	drug	NOUN
admet-942	4	18	in	in	ADP
admet-942	4	19	clinical	clinical	ADJ
admet-942	4	20	phases	phase	NOUN
admet-942	4	21	and	and	CCONJ
admet-942	4	22	have	have	VERB
admet-942	4	23	an	an	DET
admet-942	4	24	impact	impact	NOUN
admet-942	4	25	on	on	ADP
admet-942	4	26	personalized	personalized	ADJ
admet-942	4	27	therapies	therapy	NOUN
admet-942	4	28	.	.	PUNCT
admet-942	5	1	organ	organ	NOUN
admet-942	5	2	-	-	PUNCT
admet-942	5	3	on	on	ADP
admet-942	5	4	-	-	PUNCT
admet-942	5	5	a	a	DET
admet-942	5	6	-	-	PUNCT
admet-942	5	7	chip	chip	NOUN
admet-942	5	8	technology	technology	NOUN
admet-942	5	9	present	present	VERB
admet-942	5	10	higher	high	ADJ
admet-942	5	11	potential	potential	NOUN
admet-942	5	12	than	than	ADP
admet-942	5	13	traditional	traditional	ADJ
admet-942	5	14	cell	cell	NOUN
admet-942	5	15	cultures	culture	NOUN
admet-942	5	16	for	for	ADP
admet-942	5	17	an	an	DET
admet-942	5	18	appropriate	appropriate	ADJ
admet-942	5	19	prediction	prediction	NOUN
admet-942	5	20	of	of	ADP
admet-942	5	21	functional	functional	ADJ
admet-942	5	22	impairments	impairment	NOUN
admet-942	5	23	,	,	PUNCT
admet-942	5	24	appearance	appearance	NOUN
admet-942	5	25	of	of	ADP
admet-942	5	26	adverse	adverse	ADJ
admet-942	5	27	effects	effect	NOUN
admet-942	5	28	,	,	PUNCT
admet-942	5	29	the	the	DET
admet-942	5	30	pharmacokinetic	pharmacokinetic	ADJ
admet-942	5	31	and	and	CCONJ
admet-942	5	32	toxicological	toxicological	ADJ
admet-942	5	33	profile	profile	NOUN
admet-942	5	34	and	and	CCONJ
admet-942	5	35	the	the	DET
admet-942	5	36	efficacy	efficacy	NOUN
admet-942	5	37	of	of	ADP
admet-942	5	38	a	a	DET
admet-942	5	39	drug	drug	NOUN
admet-942	5	40	.	.	PUNCT
admet-942	6	1	this	this	DET
admet-942	6	2	potential	potential	NOUN
admet-942	6	3	is	be	AUX
admet-942	6	4	given	give	VERB
admet-942	6	5	by	by	ADP
admet-942	6	6	the	the	DET
admet-942	6	7	possibility	possibility	NOUN
admet-942	6	8	of	of	ADP
admet-942	6	9	placing	place	VERB
admet-942	6	10	different	different	ADJ
admet-942	6	11	cell	cell	NOUN
admet-942	6	12	lines	line	NOUN
admet-942	6	13	in	in	ADP
admet-942	6	14	a	a	DET
admet-942	6	15	three	three	NUM
admet-942	6	16	-	-	PUNCT
admet-942	6	17	dimensional	dimensional	ADJ
admet-942	6	18	-	-	PUNCT
admet-942	6	19	arranged	arrange	VERB
admet-942	6	20	polymer	polymer	NOUN
admet-942	6	21	piece	piece	NOUN
admet-942	6	22	and	and	CCONJ
admet-942	6	23	simulating	simulate	VERB
admet-942	6	24	and	and	CCONJ
admet-942	6	25	controlling	control	VERB
admet-942	6	26	specific	specific	ADJ
admet-942	6	27	conditions	condition	NOUN
admet-942	6	28	.	.	PUNCT
admet-942	7	1	thus	thus	ADV
admet-942	7	2	,	,	PUNCT
admet-942	7	3	the	the	DET
admet-942	7	4	normal	normal	ADJ
admet-942	7	5	functioning	functioning	NOUN
admet-942	7	6	of	of	ADP
admet-942	7	7	an	an	DET
admet-942	7	8	organ	organ	NOUN
admet-942	7	9	,	,	PUNCT
admet-942	7	10	tissue	tissue	NOUN
admet-942	7	11	,	,	PUNCT
admet-942	7	12	barrier	barrier	NOUN
admet-942	7	13	,	,	PUNCT
admet-942	7	14	or	or	CCONJ
admet-942	7	15	physiological	physiological	ADJ
admet-942	7	16	phenomenon	phenomenon	NOUN
admet-942	7	17	can	can	AUX
admet-942	7	18	be	be	AUX
admet-942	7	19	simulated	simulate	VERB
admet-942	7	20	,	,	PUNCT
admet-942	7	21	as	as	ADV
admet-942	7	22	well	well	ADV
admet-942	7	23	as	as	ADP
admet-942	7	24	the	the	DET
admet-942	7	25	interrelation	interrelation	NOUN
admet-942	7	26	between	between	ADP
admet-942	7	27	different	different	ADJ
admet-942	7	28	systems	system	NOUN
admet-942	7	29	.	.	PUNCT
admet-942	8	1	furthermore	furthermore	ADV
admet-942	8	2	,	,	PUNCT
admet-942	8	3	this	this	DET
admet-942	8	4	alternative	alternative	NOUN
admet-942	8	5	allows	allow	VERB
admet-942	8	6	the	the	DET
admet-942	8	7	study	study	NOUN
admet-942	8	8	of	of	ADP
admet-942	8	9	physiological	physiological	ADJ
admet-942	8	10	and	and	CCONJ
admet-942	8	11	pathophysiological	pathophysiological	ADJ
admet-942	8	12	processes	process	NOUN
admet-942	8	13	.	.	PUNCT
admet-942	9	1	its	its	PRON
admet-942	9	2	design	design	NOUN
admet-942	9	3	combines	combine	VERB
admet-942	9	4	different	different	ADJ
admet-942	9	5	disciplines	discipline	NOUN
admet-942	9	6	such	such	ADJ
admet-942	9	7	as	as	ADP
admet-942	9	8	materials	material	NOUN
admet-942	9	9	engineering	engineering	NOUN
admet-942	9	10	,	,	PUNCT
admet-942	9	11	cell	cell	NOUN
admet-942	9	12	cultures	culture	NOUN
admet-942	9	13	,	,	PUNCT
admet-942	9	14	microfluidics	microfluidic	NOUN
admet-942	9	15	and	and	CCONJ
admet-942	9	16	physiology	physiology	NOUN
admet-942	9	17	,	,	PUNCT
admet-942	9	18	among	among	ADP
admet-942	9	19	others	other	NOUN
admet-942	9	20	.	.	PUNCT
admet-942	10	1	this	this	DET
admet-942	10	2	work	work	NOUN
admet-942	10	3	presents	present	VERB
admet-942	10	4	the	the	DET
admet-942	10	5	main	main	ADJ
admet-942	10	6	considerations	consideration	NOUN
admet-942	10	7	of	of	ADP
admet-942	10	8	ooc	ooc	NOUN
admet-942	10	9	systems	system	NOUN
admet-942	10	10	,	,	PUNCT
admet-942	10	11	the	the	DET
admet-942	10	12	materials	material	NOUN
admet-942	10	13	,	,	PUNCT
admet-942	10	14	methods	method	NOUN
admet-942	10	15	and	and	CCONJ
admet-942	10	16	cell	cell	NOUN
admet-942	10	17	lines	line	NOUN
admet-942	10	18	used	use	VERB
admet-942	10	19	for	for	ADP
admet-942	10	20	their	their	PRON
admet-942	10	21	design	design	NOUN
admet-942	10	22	,	,	PUNCT
admet-942	10	23	and	and	CCONJ
admet-942	10	24	the	the	DET
admet-942	10	25	conditions	condition	NOUN
admet-942	10	26	required	require	VERB
admet-942	10	27	for	for	ADP
admet-942	10	28	their	their	PRON
admet-942	10	29	proper	proper	ADJ
admet-942	10	30	functioning	functioning	NOUN
admet-942	10	31	.	.	PUNCT
admet-942	11	1	examples	example	NOUN
admet-942	11	2	of	of	ADP
admet-942	11	3	applications	application	NOUN
admet-942	11	4	and	and	CCONJ
admet-942	11	5	main	main	ADJ
admet-942	11	6	challenges	challenge	NOUN
admet-942	11	7	for	for	ADP
admet-942	11	8	the	the	DET
admet-942	11	9	development	development	NOUN
admet-942	11	10	of	of	ADP
admet-942	11	11	more	more	ADJ
admet-942	11	12	robust	robust	ADJ
admet-942	11	13	systems	system	NOUN
admet-942	11	14	are	be	AUX
admet-942	11	15	shown	show	VERB
admet-942	11	16	.	.	PUNCT
admet-942	12	1	this	this	DET
admet-942	12	2	nonsystematic	nonsystematic	ADJ
admet-942	12	3	review	review	NOUN
admet-942	12	4	is	be	AUX
admet-942	12	5	intended	intend	VERB
admet-942	12	6	to	to	PART
admet-942	12	7	be	be	AUX
admet-942	12	8	a	a	DET
admet-942	12	9	reference	reference	NOUN
admet-942	12	10	framework	framework	NOUN
admet-942	12	11	that	that	PRON
admet-942	12	12	facilitates	facilitate	VERB
admet-942	12	13	research	research	NOUN
admet-942	12	14	focused	focus	VERB
admet-942	12	15	on	on	ADP
admet-942	12	16	the	the	DET
admet-942	12	17	development	development	NOUN
admet-942	12	18	of	of	ADP
admet-942	12	19	new	new	ADJ
admet-942	12	20	ooc	ooc	NOUN
admet-942	12	21	systems	system	NOUN
admet-942	12	22	,	,	PUNCT
admet-942	12	23	as	as	ADV
admet-942	12	24	well	well	ADV
admet-942	12	25	as	as	ADP
admet-942	12	26	their	their	PRON
admet-942	12	27	use	use	NOUN
admet-942	12	28	as	as	ADP
admet-942	12	29	alternatives	alternative	NOUN
admet-942	12	30	in	in	ADP
admet-942	12	31	pharmacological	pharmacological	NOUN
admet-942	12	32	,	,	PUNCT
admet-942	12	33	pharmacokinetic	pharmacokinetic	ADJ
admet-942	12	34	and	and	CCONJ
admet-942	12	35	toxicological	toxicological	ADJ
admet-942	12	36	studies	study	NOUN
admet-942	12	37	.	.	PUNCT
admet-942	13	1	©	©	PROPN
admet-942	13	2	2021	2021	NUM
admet-942	13	3	by	by	ADP
admet-942	13	4	the	the	DET
admet-942	13	5	authors	author	NOUN
admet-942	13	6	.	.	PUNCT
admet-942	14	1	this	this	DET
admet-942	14	2	article	article	NOUN
admet-942	14	3	is	be	AUX
admet-942	14	4	an	an	DET
admet-942	14	5	open	open	ADJ
admet-942	14	6	-	-	PUNCT
admet-942	14	7	access	access	NOUN
admet-942	14	8	article	article	NOUN
admet-942	14	9	distributed	distribute	VERB
admet-942	14	10	under	under	ADP
admet-942	14	11	the	the	DET
admet-942	14	12	terms	term	NOUN
admet-942	14	13	and	and	CCONJ
admet-942	14	14	conditions	condition	NOUN
admet-942	14	15	of	of	ADP
admet-942	14	16	the	the	DET
admet-942	14	17	creative	creative	ADJ
admet-942	14	18	commons	common	NOUN
admet-942	14	19	attribution	attribution	NOUN
admet-942	14	20	license	license	NOUN
admet-942	14	21	(	(	PUNCT
admet-942	14	22	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-942	14	23	)	)	PUNCT
admet-942	14	24	.	.	PUNCT
admet-942	15	1	keywords	keyword	VERB
admet-942	15	2	drug	drug	NOUN
admet-942	15	3	discovery	discovery	NOUN
admet-942	15	4	;	;	PUNCT
admet-942	15	5	tissue	tissue	NOUN
admet-942	15	6	engineering	engineering	NOUN
admet-942	15	7	;	;	PUNCT
admet-942	15	8	cell	cell	NOUN
admet-942	15	9	culture	culture	NOUN
admet-942	15	10	;	;	PUNCT
admet-942	15	11	preclinical	preclinical	ADJ
admet-942	15	12	models	model	NOUN
admet-942	15	13	;	;	PUNCT
admet-942	15	14	organoids	organoid	NOUN
admet-942	15	15	;	;	PUNCT
admet-942	15	16	lab	lab	NOUN
admet-942	15	17	-	-	PUNCT
admet-942	15	18	on	on	ADP
admet-942	15	19	-	-	PUNCT
admet-942	15	20	a	a	DET
admet-942	15	21	-	-	PUNCT
admet-942	15	22	chip	chip	NOUN
admet-942	15	23	devices	device	NOUN
admet-942	15	24	introduction	introduction	VERB
admet-942	15	25	the	the	DET
admet-942	15	26	development	development	NOUN
admet-942	15	27	of	of	ADP
admet-942	15	28	new	new	ADJ
admet-942	15	29	drugs	drug	NOUN
admet-942	15	30	is	be	AUX
admet-942	15	31	an	an	DET
admet-942	15	32	expensive	expensive	ADJ
admet-942	15	33	process	process	NOUN
admet-942	15	34	that	that	PRON
admet-942	15	35	presents	present	VERB
admet-942	15	36	several	several	ADJ
admet-942	15	37	challenges	challenge	NOUN
admet-942	15	38	in	in	ADP
admet-942	15	39	preclinical	preclinical	ADJ
admet-942	15	40	and	and	CCONJ
admet-942	15	41	clinical	clinical	ADJ
admet-942	15	42	studies	study	NOUN
admet-942	15	43	[	[	X
admet-942	15	44	1,2	1,2	NUM
admet-942	15	45	]	]	PUNCT
admet-942	15	46	,	,	PUNCT
admet-942	15	47	where	where	SCONJ
admet-942	15	48	a	a	DET
admet-942	15	49	59	59	NUM
admet-942	15	50	%	%	NOUN
admet-942	15	51	of	of	ADP
admet-942	15	52	the	the	DET
admet-942	15	53	medicines	medicine	NOUN
admet-942	15	54	that	that	PRON
admet-942	15	55	initiate	initiate	VERB
admet-942	15	56	a	a	DET
admet-942	15	57	clinical	clinical	ADJ
admet-942	15	58	study	study	NOUN
admet-942	15	59	go	go	VERB
admet-942	15	60	into	into	ADP
admet-942	15	61	phase	phase	NOUN
admet-942	15	62	ii	ii	NOUN
admet-942	15	63	,	,	PUNCT
admet-942	15	64	just	just	ADV
admet-942	15	65	a	a	DET
admet-942	15	66	21	21	NUM
admet-942	15	67	%	%	NOUN
admet-942	15	68	starts	start	NOUN
admet-942	15	69	phase	phase	NOUN
admet-942	15	70	iii	iii	NOUN
admet-942	15	71	,	,	PUNCT
admet-942	15	72	and	and	CCONJ
admet-942	15	73	merely	merely	ADV
admet-942	15	74	a	a	DET
admet-942	15	75	10	10	NUM
admet-942	15	76	%	%	NOUN
admet-942	15	77	reach	reach	VERB
admet-942	15	78	approval	approval	NOUN
admet-942	15	79	by	by	ADP
admet-942	15	80	the	the	DET
admet-942	15	81	regulatory	regulatory	ADJ
admet-942	15	82	authority	authority	NOUN
admet-942	15	83	.	.	PUNCT
admet-942	16	1	the	the	DET
admet-942	16	2	appearance	appearance	NOUN
admet-942	16	3	of	of	ADP
admet-942	16	4	adverse	adverse	ADJ
admet-942	16	5	effects	effect	NOUN
admet-942	16	6	is	be	AUX
admet-942	16	7	one	one	NUM
admet-942	16	8	of	of	ADP
admet-942	16	9	the	the	DET
admet-942	16	10	main	main	ADJ
admet-942	16	11	reasons	reason	NOUN
admet-942	16	12	for	for	ADP
admet-942	16	13	drug	drug	NOUN
admet-942	16	14	failure	failure	NOUN
admet-942	16	15	,	,	PUNCT
admet-942	16	16	becoming	become	VERB
admet-942	16	17	one	one	NUM
admet-942	16	18	of	of	ADP
admet-942	16	19	the	the	DET
admet-942	16	20	biggest	big	ADJ
admet-942	16	21	challenges	challenge	NOUN
admet-942	16	22	and	and	CCONJ
admet-942	16	23	weaknesses	weakness	NOUN
admet-942	16	24	presented	present	VERB
admet-942	16	25	by	by	ADP
admet-942	16	26	preclinical	preclinical	ADJ
admet-942	16	27	models	model	NOUN
admet-942	16	28	as	as	ADP
admet-942	16	29	predictors	predictor	NOUN
admet-942	16	30	of	of	ADP
admet-942	16	31	clinical	clinical	ADJ
admet-942	16	32	performance	performance	NOUN
admet-942	16	33	[	[	X
admet-942	16	34	2–5	2–5	X
admet-942	16	35	]	]	PUNCT
admet-942	16	36	.	.	PUNCT
admet-942	17	1	however	however	ADV
admet-942	17	2	,	,	PUNCT
admet-942	17	3	clinical	clinical	ADJ
admet-942	17	4	failures	failure	NOUN
admet-942	17	5	are	be	AUX
admet-942	17	6	not	not	PART
admet-942	17	7	just	just	ADV
admet-942	17	8	the	the	DET
admet-942	17	9	result	result	NOUN
admet-942	17	10	of	of	ADP
admet-942	17	11	safety	safety	NOUN
admet-942	17	12	-	-	PUNCT
admet-942	17	13	related	relate	VERB
admet-942	17	14	situations	situation	NOUN
admet-942	17	15	,	,	PUNCT
admet-942	17	16	but	but	CCONJ
admet-942	17	17	are	be	AUX
admet-942	17	18	also	also	ADV
admet-942	17	19	linked	link	VERB
admet-942	17	20	to	to	ADP
admet-942	17	21	the	the	DET
admet-942	17	22	lack	lack	NOUN
admet-942	17	23	of	of	ADP
admet-942	17	24	clinical	clinical	ADJ
admet-942	17	25	efficacy	efficacy	NOUN
admet-942	17	26	[	[	X
admet-942	17	27	6	6	NUM
admet-942	17	28	]	]	PUNCT
admet-942	17	29	.	.	PUNCT
admet-942	18	1	the	the	DET
admet-942	18	2	non	non	NOUN
admet-942	18	3	-	-	NOUN
admet-942	18	4	detection	detection	NOUN
admet-942	18	5	of	of	ADP
admet-942	18	6	side	side	NOUN
admet-942	18	7	effects	effect	NOUN
admet-942	18	8	can	can	AUX
admet-942	18	9	also	also	ADV
admet-942	18	10	become	become	VERB
admet-942	18	11	an	an	DET
admet-942	18	12	issue	issue	NOUN
admet-942	18	13	for	for	ADP
admet-942	18	14	a	a	DET
admet-942	18	15	drug	drug	NOUN
admet-942	18	16	that	that	PRON
admet-942	18	17	has	have	AUX
admet-942	18	18	already	already	ADV
admet-942	18	19	passed	pass	VERB
admet-942	18	20	the	the	DET
admet-942	18	21	clinical	clinical	ADJ
admet-942	18	22	phase	phase	NOUN
admet-942	18	23	.	.	PUNCT
admet-942	19	1	the	the	DET
admet-942	19	2	non	non	ADJ
admet-942	19	3	-	-	ADJ
admet-942	19	4	adequate	adequate	ADJ
admet-942	19	5	determination	determination	NOUN
admet-942	19	6	of	of	ADP
admet-942	19	7	adverse	adverse	ADJ
admet-942	19	8	effects	effect	NOUN
admet-942	19	9	can	can	AUX
admet-942	19	10	lead	lead	VERB
admet-942	19	11	to	to	ADP
admet-942	19	12	market	market	NOUN
admet-942	19	13	recalls	recall	VERB
admet-942	19	14	.	.	PUNCT
admet-942	20	1	these	these	PRON
admet-942	20	2	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	20	3	http://dx.doi.org/10.5599/admet.942	http://dx.doi.org/10.5599/admet.942	ADJ
admet-942	20	4	http://www.pub.iapchem.org/ojs/index.php/admet/index	http://www.pub.iapchem.org/ojs/index.php/admet/index	PROPN
admet-942	20	5	mailto:ronny.vargas_m@ucr.ac.cr	mailto:ronny.vargas_m@ucr.ac.cr	PROPN
admet-942	20	6	http://creativecommons.org/licenses/by/4.0/	http://creativecommons.org/licenses/by/4.0/	PROPN
admet-942	20	7	r.	r.	PROPN
admet-942	20	8	vargas	vargas	PROPN
admet-942	20	9	,	,	PUNCT
admet-942	20	10	a.	a.	NOUN
admet-942	20	11	egurbide	egurbide	NOUN
admet-942	20	12	-	-	PUNCT
admet-942	20	13	sifre	sifre	NOUN
admet-942	20	14	and	and	CCONJ
admet-942	20	15	l.	l.	PROPN
admet-942	20	16	medina	medina	PROPN
admet-942	20	17	admet	admet	PROPN
admet-942	20	18	&	&	CCONJ
admet-942	20	19	dmpk	dmpk	PROPN
admet-942	20	20	9(2	9(2	NUM
admet-942	20	21	)	)	PUNCT
admet-942	20	22	(	(	PUNCT
admet-942	20	23	2021	2021	NUM
admet-942	20	24	)	)	PUNCT
admet-942	20	25	111	111	NUM
admet-942	20	26	-	-	SYM
admet-942	20	27	141	141	NUM
admet-942	20	28	112	112	NUM
admet-942	20	29	unwanted	unwanted	ADJ
admet-942	20	30	events	event	NOUN
admet-942	20	31	are	be	AUX
admet-942	20	32	mainly	mainly	ADV
admet-942	20	33	liveror	liveror	ADJ
admet-942	20	34	heart	heart	NOUN
admet-942	20	35	-	-	PUNCT
admet-942	20	36	related	relate	VERB
admet-942	20	37	,	,	PUNCT
admet-942	20	38	due	due	ADP
admet-942	20	39	to	to	ADP
admet-942	20	40	the	the	DET
admet-942	20	41	effect	effect	NOUN
admet-942	20	42	of	of	ADP
admet-942	20	43	metabolite	metabolite	NOUN
admet-942	20	44	generation	generation	NOUN
admet-942	20	45	[	[	X
admet-942	20	46	5,7	5,7	NUM
admet-942	20	47	]	]	PUNCT
admet-942	20	48	.	.	PUNCT
admet-942	21	1	animal	animal	NOUN
admet-942	21	2	models	model	NOUN
admet-942	21	3	applied	apply	VERB
admet-942	21	4	in	in	ADP
admet-942	21	5	preclinical	preclinical	ADJ
admet-942	21	6	phases	phase	NOUN
admet-942	21	7	are	be	AUX
admet-942	21	8	often	often	ADV
admet-942	21	9	unrepresentative	unrepresentative	ADJ
admet-942	21	10	to	to	ADP
admet-942	21	11	the	the	DET
admet-942	21	12	human	human	ADJ
admet-942	21	13	body	body	NOUN
admet-942	21	14	,	,	PUNCT
admet-942	21	15	thus	thus	ADV
admet-942	21	16	failing	fail	VERB
admet-942	21	17	in	in	ADP
admet-942	21	18	the	the	DET
admet-942	21	19	prediction	prediction	NOUN
admet-942	21	20	of	of	ADP
admet-942	21	21	the	the	DET
admet-942	21	22	efficacy	efficacy	NOUN
admet-942	21	23	and	and	CCONJ
admet-942	21	24	safety	safety	NOUN
admet-942	21	25	of	of	ADP
admet-942	21	26	drugs	drug	NOUN
admet-942	21	27	[	[	X
admet-942	21	28	1,3,4,8,9	1,3,4,8,9	NUM
admet-942	21	29	]	]	PUNCT
admet-942	21	30	.	.	PUNCT
admet-942	22	1	however	however	ADV
admet-942	22	2	,	,	PUNCT
admet-942	22	3	clinical	clinical	ADJ
admet-942	22	4	failures	failure	NOUN
admet-942	22	5	might	might	AUX
admet-942	22	6	be	be	AUX
admet-942	22	7	mitigated	mitigate	VERB
admet-942	22	8	by	by	ADP
admet-942	22	9	adding	add	VERB
admet-942	22	10	models	model	NOUN
admet-942	22	11	with	with	ADP
admet-942	22	12	a	a	DET
admet-942	22	13	superior	superior	ADJ
admet-942	22	14	predictor	predictor	NOUN
admet-942	22	15	capacity	capacity	NOUN
admet-942	22	16	in	in	ADP
admet-942	22	17	preclinical	preclinical	ADJ
admet-942	22	18	phases	phase	NOUN
admet-942	22	19	[	[	X
admet-942	22	20	10	10	NUM
admet-942	22	21	]	]	PUNCT
admet-942	22	22	.	.	PUNCT
admet-942	23	1	the	the	DET
admet-942	23	2	use	use	NOUN
admet-942	23	3	of	of	ADP
admet-942	23	4	traditional	traditional	ADJ
admet-942	23	5	twodimensional	twodimensional	ADJ
admet-942	23	6	(	(	PUNCT
admet-942	23	7	2d	2d	NOUN
admet-942	23	8	)	)	PUNCT
admet-942	23	9	cell	cell	NOUN
admet-942	23	10	cultures	culture	NOUN
admet-942	23	11	has	have	AUX
admet-942	23	12	made	make	VERB
admet-942	23	13	great	great	ADJ
admet-942	23	14	contributions	contribution	NOUN
admet-942	23	15	to	to	ADP
admet-942	23	16	medicine	medicine	NOUN
admet-942	23	17	so	so	ADV
admet-942	23	18	far	far	ADV
admet-942	23	19	,	,	PUNCT
admet-942	23	20	and	and	CCONJ
admet-942	23	21	it	it	PRON
admet-942	23	22	has	have	AUX
admet-942	23	23	led	lead	VERB
admet-942	23	24	to	to	PART
admet-942	23	25	reduce	reduce	VERB
admet-942	23	26	the	the	DET
admet-942	23	27	use	use	NOUN
admet-942	23	28	of	of	ADP
admet-942	23	29	laboratory	laboratory	NOUN
admet-942	23	30	animals	animal	NOUN
admet-942	23	31	.	.	PUNCT
admet-942	24	1	however	however	ADV
admet-942	24	2	,	,	PUNCT
admet-942	24	3	these	these	DET
admet-942	24	4	systems	system	NOUN
admet-942	24	5	do	do	AUX
admet-942	24	6	not	not	PART
admet-942	24	7	allow	allow	VERB
admet-942	24	8	the	the	DET
admet-942	24	9	study	study	NOUN
admet-942	24	10	of	of	ADP
admet-942	24	11	tissue	tissue	NOUN
admet-942	24	12	’s	’s	PART
admet-942	24	13	microenvironment	microenvironment	NOUN
admet-942	24	14	or	or	CCONJ
admet-942	24	15	the	the	DET
admet-942	24	16	complex	complex	ADJ
admet-942	24	17	interrelationships	interrelationship	NOUN
admet-942	24	18	between	between	ADP
admet-942	24	19	different	different	ADJ
admet-942	24	20	tissues	tissue	NOUN
admet-942	24	21	and	and	CCONJ
admet-942	24	22	organs	organ	NOUN
admet-942	24	23	of	of	ADP
admet-942	24	24	the	the	DET
admet-942	24	25	human	human	ADJ
admet-942	24	26	body	body	NOUN
admet-942	24	27	.	.	PUNCT
admet-942	25	1	moreover	moreover	ADV
admet-942	25	2	,	,	PUNCT
admet-942	25	3	the	the	DET
admet-942	25	4	study	study	NOUN
admet-942	25	5	of	of	ADP
admet-942	25	6	isolated	isolated	ADJ
admet-942	25	7	cells	cell	NOUN
admet-942	25	8	without	without	ADP
admet-942	25	9	a	a	DET
admet-942	25	10	systematic	systematic	ADJ
admet-942	25	11	functional	functional	ADJ
admet-942	25	12	evaluation	evaluation	NOUN
admet-942	25	13	presents	present	VERB
admet-942	25	14	the	the	DET
admet-942	25	15	risk	risk	NOUN
admet-942	25	16	of	of	ADP
admet-942	25	17	ignoring	ignore	VERB
admet-942	25	18	structural	structural	ADJ
admet-942	25	19	alterations	alteration	NOUN
admet-942	25	20	that	that	PRON
admet-942	25	21	may	may	AUX
admet-942	25	22	have	have	VERB
admet-942	25	23	an	an	DET
admet-942	25	24	impact	impact	NOUN
admet-942	25	25	on	on	ADP
admet-942	25	26	the	the	DET
admet-942	25	27	organ	organ	NOUN
admet-942	25	28	’s	’s	PART
admet-942	25	29	function	function	NOUN
admet-942	25	30	,	,	PUNCT
admet-942	25	31	even	even	ADV
admet-942	25	32	if	if	SCONJ
admet-942	25	33	those	those	DET
admet-942	25	34	isolated	isolated	ADJ
admet-942	25	35	cells	cell	NOUN
admet-942	25	36	remained	remain	VERB
admet-942	25	37	viable	viable	ADJ
admet-942	25	38	[	[	X
admet-942	25	39	1,10	1,10	NUM
admet-942	25	40	]	]	PUNCT
admet-942	25	41	.	.	PUNCT
admet-942	26	1	in	in	ADP
admet-942	26	2	recent	recent	ADJ
admet-942	26	3	years	year	NOUN
admet-942	26	4	,	,	PUNCT
admet-942	26	5	the	the	DET
admet-942	26	6	organ	organ	NOUN
admet-942	26	7	-	-	PUNCT
admet-942	26	8	on	on	ADP
admet-942	26	9	-	-	PUNCT
admet-942	26	10	a	a	DET
admet-942	26	11	-	-	PUNCT
admet-942	26	12	chip	chip	NOUN
admet-942	26	13	(	(	PUNCT
admet-942	26	14	ooc	ooc	NOUN
admet-942	26	15	)	)	PUNCT
admet-942	26	16	technology	technology	NOUN
admet-942	26	17	has	have	AUX
admet-942	26	18	emerged	emerge	VERB
admet-942	26	19	as	as	ADP
admet-942	26	20	an	an	DET
admet-942	26	21	alternative	alternative	NOUN
admet-942	26	22	in	in	ADP
admet-942	26	23	drug	drug	NOUN
admet-942	26	24	development	development	NOUN
admet-942	26	25	,	,	PUNCT
admet-942	26	26	as	as	SCONJ
admet-942	26	27	it	it	PRON
admet-942	26	28	aims	aim	VERB
admet-942	26	29	to	to	PART
admet-942	26	30	reflect	reflect	VERB
admet-942	26	31	the	the	DET
admet-942	26	32	environmental	environmental	ADJ
admet-942	26	33	,	,	PUNCT
admet-942	26	34	functional	functional	ADJ
admet-942	26	35	,	,	PUNCT
admet-942	26	36	and	and	CCONJ
admet-942	26	37	interrelationship	interrelationship	NOUN
admet-942	26	38	characteristics	characteristic	NOUN
admet-942	26	39	of	of	ADP
admet-942	26	40	organs	organ	NOUN
admet-942	26	41	and	and	CCONJ
admet-942	26	42	tissues	tissue	NOUN
admet-942	26	43	[	[	X
admet-942	26	44	2,11	2,11	NOUN
admet-942	26	45	]	]	PUNCT
admet-942	26	46	.	.	PUNCT
admet-942	27	1	the	the	DET
admet-942	27	2	concept	concept	NOUN
admet-942	27	3	of	of	ADP
admet-942	27	4	reproducing	reproduce	VERB
admet-942	27	5	organic	organic	ADJ
admet-942	27	6	and	and	CCONJ
admet-942	27	7	physiological	physiological	ADJ
admet-942	27	8	functions	function	NOUN
admet-942	27	9	of	of	ADP
admet-942	27	10	the	the	DET
admet-942	27	11	human	human	ADJ
admet-942	27	12	body	body	NOUN
admet-942	27	13	by	by	ADP
admet-942	27	14	using	use	VERB
admet-942	27	15	cells	cell	NOUN
admet-942	27	16	within	within	ADP
admet-942	27	17	a	a	DET
admet-942	27	18	microfluidic	microfluidic	ADJ
admet-942	27	19	chip	chip	NOUN
admet-942	27	20	was	be	AUX
admet-942	27	21	first	first	ADV
admet-942	27	22	published	publish	VERB
admet-942	27	23	in	in	ADP
admet-942	27	24	2004	2004	NUM
admet-942	27	25	,	,	PUNCT
admet-942	27	26	when	when	SCONJ
admet-942	27	27	shuler	shuler	PROPN
admet-942	27	28	et	et	PROPN
admet-942	27	29	al	al	PROPN
admet-942	27	30	.	.	PROPN
admet-942	27	31	showed	show	VERB
admet-942	27	32	a	a	DET
admet-942	27	33	cell	cell	NOUN
admet-942	27	34	culture	culture	NOUN
admet-942	27	35	that	that	PRON
admet-942	27	36	exemplified	exemplify	VERB
admet-942	27	37	the	the	DET
admet-942	27	38	interaction	interaction	NOUN
admet-942	27	39	between	between	ADP
admet-942	27	40	the	the	DET
admet-942	27	41	lung	lung	NOUN
admet-942	27	42	and	and	CCONJ
admet-942	27	43	the	the	DET
admet-942	27	44	liver	liver	NOUN
admet-942	27	45	on	on	ADP
admet-942	27	46	a	a	DET
admet-942	27	47	square	square	ADJ
admet-942	27	48	-	-	PUNCT
admet-942	27	49	inch	inch	NOUN
admet-942	27	50	silicone	silicone	NOUN
admet-942	27	51	chip	chip	NOUN
admet-942	27	52	.	.	PUNCT
admet-942	28	1	the	the	DET
admet-942	28	2	term	term	NOUN
admet-942	28	3	organ	organ	NOUN
admet-942	28	4	-	-	PUNCT
admet-942	28	5	on	on	ADP
admet-942	28	6	-	-	PUNCT
admet-942	28	7	a	a	DET
admet-942	28	8	-	-	PUNCT
admet-942	28	9	chip	chip	NOUN
admet-942	28	10	was	be	AUX
admet-942	28	11	adopted	adopt	VERB
admet-942	28	12	in	in	ADP
admet-942	28	13	2010	2010	NUM
admet-942	28	14	[	[	X
admet-942	28	15	2,7,12,13	2,7,12,13	NUM
admet-942	28	16	]	]	PUNCT
admet-942	28	17	.	.	PUNCT
admet-942	29	1	compared	compare	VERB
admet-942	29	2	with	with	ADP
admet-942	29	3	traditional	traditional	ADJ
admet-942	29	4	models	model	NOUN
admet-942	29	5	,	,	PUNCT
admet-942	29	6	this	this	DET
admet-942	29	7	technique	technique	NOUN
admet-942	29	8	provides	provide	VERB
admet-942	29	9	improved	improved	ADJ
admet-942	29	10	information	information	NOUN
admet-942	29	11	about	about	ADP
admet-942	29	12	cells	cell	NOUN
admet-942	29	13	mechanical	mechanical	ADJ
admet-942	29	14	properties	property	NOUN
admet-942	29	15	,	,	PUNCT
admet-942	29	16	morphology	morphology	NOUN
admet-942	29	17	,	,	PUNCT
admet-942	29	18	and	and	CCONJ
admet-942	29	19	differentiation	differentiation	NOUN
admet-942	29	20	,	,	PUNCT
admet-942	29	21	among	among	ADP
admet-942	29	22	others	other	NOUN
admet-942	29	23	.	.	PUNCT
admet-942	30	1	ooc	ooc	PRON
admet-942	30	2	improve	improve	VERB
admet-942	30	3	the	the	DET
admet-942	30	4	determination	determination	NOUN
admet-942	30	5	of	of	ADP
admet-942	30	6	cell	cell	NOUN
admet-942	30	7	responses	response	NOUN
admet-942	30	8	,	,	PUNCT
admet-942	30	9	genetic	genetic	ADJ
admet-942	30	10	expressions	expression	NOUN
admet-942	30	11	,	,	PUNCT
admet-942	30	12	and	and	CCONJ
admet-942	30	13	cell	cell	NOUN
admet-942	30	14	function	function	NOUN
admet-942	30	15	.	.	PUNCT
admet-942	31	1	these	these	DET
admet-942	31	2	systems	system	NOUN
admet-942	31	3	can	can	AUX
admet-942	31	4	have	have	VERB
admet-942	31	5	an	an	DET
admet-942	31	6	impact	impact	NOUN
admet-942	31	7	on	on	ADP
admet-942	31	8	the	the	DET
admet-942	31	9	candidates	candidate	NOUN
admet-942	31	10	selection	selection	NOUN
admet-942	31	11	and	and	CCONJ
admet-942	31	12	evaluation	evaluation	NOUN
admet-942	31	13	for	for	ADP
admet-942	31	14	the	the	DET
admet-942	31	15	development	development	NOUN
admet-942	31	16	of	of	ADP
admet-942	31	17	new	new	ADJ
admet-942	31	18	medicines	medicine	NOUN
admet-942	31	19	,	,	PUNCT
admet-942	31	20	as	as	SCONJ
admet-942	31	21	they	they	PRON
admet-942	31	22	allow	allow	VERB
admet-942	31	23	gaining	gain	VERB
admet-942	31	24	information	information	NOUN
admet-942	31	25	about	about	ADP
admet-942	31	26	metabolites	metabolite	NOUN
admet-942	31	27	secretion	secretion	NOUN
admet-942	31	28	performed	perform	VERB
admet-942	31	29	by	by	ADP
admet-942	31	30	certain	certain	ADJ
admet-942	31	31	cells	cell	NOUN
admet-942	31	32	when	when	SCONJ
admet-942	31	33	interacting	interact	VERB
admet-942	31	34	with	with	ADP
admet-942	31	35	drugs	drug	NOUN
admet-942	31	36	[	[	X
admet-942	31	37	1	1	NUM
admet-942	31	38	]	]	PUNCT
admet-942	31	39	.	.	PUNCT
admet-942	32	1	furthermore	furthermore	ADV
admet-942	32	2	,	,	PUNCT
admet-942	32	3	ooc	ooc	PRON
admet-942	32	4	have	have	VERB
admet-942	32	5	the	the	DET
admet-942	32	6	potential	potential	NOUN
admet-942	32	7	to	to	PART
admet-942	32	8	reduce	reduce	VERB
admet-942	32	9	and	and	CCONJ
admet-942	32	10	supplement	supplement	VERB
admet-942	32	11	the	the	DET
admet-942	32	12	use	use	NOUN
admet-942	32	13	of	of	ADP
admet-942	32	14	animals	animal	NOUN
admet-942	32	15	,	,	PUNCT
admet-942	32	16	cell	cell	NOUN
admet-942	32	17	models	model	NOUN
admet-942	32	18	,	,	PUNCT
admet-942	32	19	and	and	CCONJ
admet-942	32	20	even	even	ADV
admet-942	32	21	humans	human	NOUN
admet-942	32	22	in	in	ADP
admet-942	32	23	new	new	ADJ
admet-942	32	24	drugs	drug	NOUN
admet-942	32	25	development	development	NOUN
admet-942	32	26	[	[	X
admet-942	32	27	7	7	NUM
admet-942	32	28	]	]	PUNCT
admet-942	32	29	.	.	PUNCT
admet-942	33	1	ooc	ooc	NOUN
admet-942	33	2	systems	system	NOUN
admet-942	33	3	offer	offer	VERB
admet-942	33	4	a	a	DET
admet-942	33	5	better	well	ADJ
admet-942	33	6	understanding	understanding	NOUN
admet-942	33	7	of	of	ADP
admet-942	33	8	pathophysiology	pathophysiology	NOUN
admet-942	33	9	,	,	PUNCT
admet-942	33	10	allowing	allow	VERB
admet-942	33	11	new	new	ADJ
admet-942	33	12	drugs	drug	NOUN
admet-942	33	13	design	design	VERB
admet-942	33	14	into	into	ADP
admet-942	33	15	specific	specific	ADJ
admet-942	33	16	mechanisms	mechanism	NOUN
admet-942	33	17	and	and	CCONJ
admet-942	33	18	promote	promote	VERB
admet-942	33	19	therapeutic	therapeutic	ADJ
admet-942	33	20	development	development	NOUN
admet-942	33	21	for	for	ADP
admet-942	33	22	pathologies	pathology	NOUN
admet-942	33	23	such	such	ADJ
admet-942	33	24	as	as	ADP
admet-942	33	25	cancer	cancer	NOUN
admet-942	33	26	,	,	PUNCT
admet-942	33	27	neurological	neurological	ADJ
admet-942	33	28	disorders	disorder	NOUN
admet-942	33	29	,	,	PUNCT
admet-942	33	30	and	and	CCONJ
admet-942	33	31	orphan	orphan	NOUN
admet-942	33	32	diseases	disease	NOUN
admet-942	33	33	[	[	X
admet-942	33	34	2	2	NUM
admet-942	33	35	]	]	PUNCT
admet-942	33	36	.	.	PUNCT
admet-942	34	1	choi	choi	PROPN
admet-942	34	2	et	et	PROPN
admet-942	34	3	al	al	PROPN
admet-942	34	4	.	.	PROPN
admet-942	34	5	used	use	VERB
admet-942	34	6	a	a	DET
admet-942	34	7	tridimensional	tridimensional	ADJ
admet-942	34	8	(	(	PUNCT
admet-942	34	9	3d	3d	NOUN
admet-942	34	10	)	)	PUNCT
admet-942	34	11	cancer	cancer	NOUN
admet-942	34	12	model	model	NOUN
admet-942	34	13	for	for	ADP
admet-942	34	14	the	the	DET
admet-942	34	15	selection	selection	NOUN
admet-942	34	16	of	of	ADP
admet-942	34	17	a	a	DET
admet-942	34	18	most	most	ADV
admet-942	34	19	effective	effective	ADJ
admet-942	34	20	drug	drug	NOUN
admet-942	34	21	against	against	ADP
admet-942	34	22	lung	lung	NOUN
admet-942	34	23	cancer	cancer	NOUN
admet-942	34	24	cells	cell	NOUN
admet-942	34	25	[	[	X
admet-942	34	26	14	14	NUM
admet-942	34	27	]	]	PUNCT
admet-942	34	28	.	.	PUNCT
admet-942	35	1	liu	liu	PROPN
admet-942	35	2	et	et	PROPN
admet-942	35	3	al	al	PROPN
admet-942	35	4	.	.	PROPN
admet-942	36	1	studied	study	VERB
admet-942	36	2	brain	brain	NOUN
admet-942	36	3	metastasis	metastasis	NOUN
admet-942	36	4	with	with	ADP
admet-942	36	5	a	a	DET
admet-942	36	6	multi	multi	ADJ
admet-942	36	7	-	-	ADJ
admet-942	36	8	organ	organ	ADJ
admet-942	36	9	chip	chip	NOUN
admet-942	36	10	that	that	PRON
admet-942	36	11	showed	show	VERB
admet-942	36	12	functional	functional	ADJ
admet-942	36	13	barrier	barrier	NOUN
admet-942	36	14	characteristics	characteristic	NOUN
admet-942	36	15	[	[	X
admet-942	36	16	15	15	NUM
admet-942	36	17	]	]	PUNCT
admet-942	36	18	.	.	PUNCT
admet-942	37	1	during	during	ADP
admet-942	37	2	the	the	DET
admet-942	37	3	covid-19	covid-19	PROPN
admet-942	37	4	pandemic	pandemic	NOUN
admet-942	37	5	caused	cause	VERB
admet-942	37	6	by	by	ADP
admet-942	37	7	the	the	DET
admet-942	37	8	sars	sar	NOUN
admet-942	37	9	-	-	PUNCT
admet-942	37	10	cov-2	cov-2	NOUN
admet-942	37	11	in	in	ADP
admet-942	37	12	2020	2020	NUM
admet-942	37	13	,	,	PUNCT
admet-942	37	14	and	and	CCONJ
admet-942	37	15	in	in	ADP
admet-942	37	16	the	the	DET
admet-942	37	17	middle	middle	NOUN
admet-942	37	18	of	of	ADP
admet-942	37	19	a	a	DET
admet-942	37	20	global	global	ADJ
admet-942	37	21	race	race	NOUN
admet-942	37	22	to	to	PART
admet-942	37	23	slow	slow	VERB
admet-942	37	24	down	down	ADP
admet-942	37	25	the	the	DET
admet-942	37	26	progression	progression	NOUN
admet-942	37	27	of	of	ADP
admet-942	37	28	the	the	DET
admet-942	37	29	disease	disease	NOUN
admet-942	37	30	,	,	PUNCT
admet-942	37	31	oocs	ooc	NOUN
admet-942	37	32	were	be	AUX
admet-942	37	33	applied	apply	VERB
admet-942	37	34	in	in	ADP
admet-942	37	35	the	the	DET
admet-942	37	36	research	research	NOUN
admet-942	37	37	for	for	ADP
admet-942	37	38	treatments	treatment	NOUN
admet-942	37	39	with	with	ADP
admet-942	37	40	fast	fast	ADJ
admet-942	37	41	and	and	CCONJ
admet-942	37	42	reliable	reliable	ADJ
admet-942	37	43	results	result	NOUN
admet-942	37	44	on	on	ADP
admet-942	37	45	the	the	DET
admet-942	37	46	preclinical	preclinical	ADJ
admet-942	37	47	scale	scale	NOUN
admet-942	37	48	[	[	X
admet-942	37	49	16	16	NUM
admet-942	37	50	]	]	PUNCT
admet-942	37	51	.	.	PUNCT
admet-942	38	1	the	the	DET
admet-942	38	2	development	development	NOUN
admet-942	38	3	of	of	ADP
admet-942	38	4	these	these	DET
admet-942	38	5	models	model	NOUN
admet-942	38	6	brought	bring	VERB
admet-942	38	7	to	to	ADP
admet-942	38	8	the	the	DET
admet-942	38	9	emergence	emergence	NOUN
admet-942	38	10	of	of	ADP
admet-942	38	11	an	an	DET
admet-942	38	12	industry	industry	NOUN
admet-942	38	13	with	with	ADP
admet-942	38	14	more	more	ADJ
admet-942	38	15	than	than	ADP
admet-942	38	16	28	28	NUM
admet-942	38	17	companies	company	NOUN
admet-942	38	18	founded	found	VERB
admet-942	38	19	in	in	ADP
admet-942	38	20	7	7	NUM
admet-942	38	21	years	year	NOUN
admet-942	38	22	[	[	X
admet-942	38	23	7,17,18	7,17,18	X
admet-942	38	24	]	]	X
admet-942	38	25	.	.	PUNCT
admet-942	39	1	hundreds	hundred	NOUN
admet-942	39	2	of	of	ADP
admet-942	39	3	publications	publication	NOUN
admet-942	39	4	are	be	AUX
admet-942	39	5	generated	generate	VERB
admet-942	39	6	each	each	DET
admet-942	39	7	year	year	NOUN
admet-942	39	8	regarding	regard	VERB
admet-942	39	9	this	this	DET
admet-942	39	10	topic	topic	NOUN
admet-942	39	11	,	,	PUNCT
admet-942	39	12	which	which	PRON
admet-942	39	13	rises	rise	VERB
admet-942	39	14	the	the	DET
admet-942	39	15	interest	interest	NOUN
admet-942	39	16	of	of	ADP
admet-942	39	17	companies	company	NOUN
admet-942	39	18	carrying	carry	VERB
admet-942	39	19	out	out	ADP
admet-942	39	20	basic	basic	ADJ
admet-942	39	21	research	research	NOUN
admet-942	39	22	in	in	ADP
admet-942	39	23	the	the	DET
admet-942	39	24	field	field	NOUN
admet-942	39	25	of	of	ADP
admet-942	39	26	drugs	drug	NOUN
admet-942	39	27	and	and	CCONJ
admet-942	39	28	also	also	ADV
admet-942	39	29	in	in	ADP
admet-942	39	30	other	other	ADJ
admet-942	39	31	areas	area	NOUN
admet-942	39	32	such	such	ADJ
admet-942	39	33	as	as	ADP
admet-942	39	34	cosmetics	cosmetic	NOUN
admet-942	39	35	,	,	PUNCT
admet-942	39	36	food	food	NOUN
admet-942	39	37	and	and	CCONJ
admet-942	39	38	medical	medical	ADJ
admet-942	39	39	devices	device	NOUN
admet-942	39	40	[	[	X
admet-942	39	41	8,11,19–22	8,11,19–22	NUM
admet-942	39	42	]	]	PUNCT
admet-942	39	43	.	.	PUNCT
admet-942	40	1	some	some	PRON
admet-942	40	2	of	of	ADP
admet-942	40	3	the	the	DET
admet-942	40	4	synonyms	synonym	NOUN
admet-942	40	5	under	under	ADP
admet-942	40	6	which	which	PRON
admet-942	40	7	ooc	ooc	PRON
admet-942	40	8	can	can	AUX
admet-942	40	9	be	be	AUX
admet-942	40	10	found	find	VERB
admet-942	40	11	in	in	ADP
admet-942	40	12	the	the	DET
admet-942	40	13	literature	literature	NOUN
admet-942	40	14	are	be	AUX
admet-942	40	15	the	the	DET
admet-942	40	16	following	following	ADJ
admet-942	40	17	ones	one	NOUN
admet-942	40	18	:	:	PUNCT
admet-942	40	19	lab	lab	NOUN
admet-942	40	20	-	-	PUNCT
admet-942	40	21	on	on	ADP
admet-942	40	22	-	-	PUNCT
admet-942	40	23	achip	achip	NOUN
admet-942	40	24	[	[	X
admet-942	40	25	17	17	NUM
admet-942	40	26	]	]	PUNCT
admet-942	40	27	,	,	PUNCT
admet-942	40	28	organoids	organoid	NOUN
admet-942	40	29	-	-	PUNCT
admet-942	40	30	on	on	ADP
admet-942	40	31	-	-	PUNCT
admet-942	40	32	chip	chip	NOUN
admet-942	40	33	[	[	X
admet-942	40	34	23	23	NUM
admet-942	40	35	]	]	PUNCT
admet-942	40	36	,	,	PUNCT
admet-942	40	37	organ	organ	NOUN
admet-942	40	38	-	-	PUNCT
admet-942	40	39	on	on	ADP
admet-942	40	40	-	-	PUNCT
admet-942	40	41	a	a	PRON
admet-942	40	42	-	-	PUNCT
admet-942	40	43	plate[6	plate[6	NOUN
admet-942	40	44	]	]	PUNCT
admet-942	40	45	,	,	PUNCT
admet-942	40	46	tissue	tissue	NOUN
admet-942	40	47	-	-	PUNCT
admet-942	40	48	on	on	ADP
admet-942	40	49	-	-	PUNCT
admet-942	40	50	chip	chip	NOUN
admet-942	40	51	[	[	X
admet-942	40	52	9	9	NUM
admet-942	40	53	]	]	PUNCT
admet-942	40	54	,	,	PUNCT
admet-942	40	55	microphysiological	microphysiological	ADJ
admet-942	40	56	system	system	NOUN
admet-942	40	57	(	(	PUNCT
admet-942	40	58	mps)[6	mps)[6	X
admet-942	40	59	]	]	PUNCT
admet-942	40	60	,	,	PUNCT
admet-942	40	61	and	and	CCONJ
admet-942	40	62	mps	mp	NOUN
admet-942	40	63	-	-	PUNCT
admet-942	40	64	based	base	VERB
admet-942	40	65	organ	organ	NOUN
admet-942	40	66	model	model	NOUN
admet-942	40	67	[	[	X
admet-942	40	68	24	24	NUM
admet-942	40	69	]	]	PUNCT
admet-942	40	70	.	.	PUNCT
admet-942	41	1	this	this	DET
admet-942	41	2	work	work	NOUN
admet-942	41	3	is	be	AUX
admet-942	41	4	intended	intend	VERB
admet-942	41	5	to	to	PART
admet-942	41	6	be	be	AUX
admet-942	41	7	a	a	DET
admet-942	41	8	reference	reference	NOUN
admet-942	41	9	framework	framework	NOUN
admet-942	41	10	that	that	PRON
admet-942	41	11	facilitates	facilitate	VERB
admet-942	41	12	research	research	NOUN
admet-942	41	13	focused	focus	VERB
admet-942	41	14	on	on	ADP
admet-942	41	15	the	the	DET
admet-942	41	16	development	development	NOUN
admet-942	41	17	of	of	ADP
admet-942	41	18	new	new	ADJ
admet-942	41	19	ooc	ooc	NOUN
admet-942	41	20	systems	system	NOUN
admet-942	41	21	,	,	PUNCT
admet-942	41	22	as	as	ADV
admet-942	41	23	well	well	ADV
admet-942	41	24	as	as	ADP
admet-942	41	25	their	their	PRON
admet-942	41	26	use	use	NOUN
admet-942	41	27	as	as	ADP
admet-942	41	28	alternative	alternative	ADJ
admet-942	41	29	in	in	ADP
admet-942	41	30	pharmacological	pharmacological	NOUN
admet-942	41	31	,	,	PUNCT
admet-942	41	32	pharmacokinetic	pharmacokinetic	ADJ
admet-942	41	33	and	and	CCONJ
admet-942	41	34	toxicological	toxicological	ADJ
admet-942	41	35	studies	study	NOUN
admet-942	41	36	with	with	ADP
admet-942	41	37	the	the	DET
admet-942	41	38	aim	aim	NOUN
admet-942	41	39	of	of	ADP
admet-942	41	40	making	make	VERB
admet-942	41	41	them	they	PRON
admet-942	41	42	become	become	VERB
admet-942	41	43	a	a	DET
admet-942	41	44	more	more	ADV
admet-942	41	45	powerful	powerful	ADJ
admet-942	41	46	,	,	PUNCT
admet-942	41	47	accurate	accurate	ADJ
admet-942	41	48	and	and	CCONJ
admet-942	41	49	used	use	VERB
admet-942	41	50	research	research	NOUN
admet-942	41	51	tool	tool	NOUN
admet-942	41	52	in	in	ADP
admet-942	41	53	drug	drug	NOUN
admet-942	41	54	development	development	NOUN
admet-942	41	55	.	.	PUNCT
admet-942	42	1	ooc	ooc	PRON
admet-942	42	2	basic	basic	ADJ
admet-942	42	3	features	feature	VERB
admet-942	42	4	this	this	DET
admet-942	42	5	field	field	NOUN
admet-942	42	6	of	of	ADP
admet-942	42	7	study	study	NOUN
admet-942	42	8	emerges	emerge	VERB
admet-942	42	9	as	as	ADP
admet-942	42	10	a	a	DET
admet-942	42	11	combination	combination	NOUN
admet-942	42	12	of	of	ADP
admet-942	42	13	cellular	cellular	ADJ
admet-942	42	14	biology	biology	NOUN
admet-942	42	15	,	,	PUNCT
admet-942	42	16	cell	cell	NOUN
admet-942	42	17	culture	culture	NOUN
admet-942	42	18	engineering	engineering	NOUN
admet-942	42	19	,	,	PUNCT
admet-942	42	20	microsystem	microsystem	NOUN
admet-942	42	21	admet	admet	PROPN
admet-942	42	22	&	&	CCONJ
admet-942	42	23	dmpk	dmpk	PROPN
admet-942	42	24	9(2	9(2	NUM
admet-942	42	25	)	)	PUNCT
admet-942	42	26	(	(	PUNCT
admet-942	42	27	2021	2021	NUM
admet-942	42	28	)	)	PUNCT
admet-942	42	29	111	111	NUM
admet-942	42	30	-	-	SYM
admet-942	42	31	141	141	NUM
admet-942	42	32	organ	organ	NOUN
admet-942	42	33	-	-	PUNCT
admet-942	42	34	on	on	ADP
admet-942	42	35	-	-	PUNCT
admet-942	42	36	a	a	DET
admet-942	42	37	-	-	PUNCT
admet-942	42	38	chip	chip	NOUN
admet-942	42	39	systems	system	NOUN
admet-942	42	40	for	for	ADP
admet-942	42	41	new	new	ADJ
admet-942	42	42	drugs	drug	NOUN
admet-942	42	43	development	development	NOUN
admet-942	42	44	doi	doi	PROPN
admet-942	42	45	:	:	PUNCT
admet-942	42	46	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	42	47	113	113	NUM
admet-942	42	48	engineering	engineering	NOUN
admet-942	42	49	,	,	PUNCT
admet-942	42	50	microfluidic	microfluidic	ADJ
admet-942	42	51	studies	study	NOUN
admet-942	42	52	,	,	PUNCT
admet-942	42	53	and	and	CCONJ
admet-942	42	54	materials	material	NOUN
admet-942	42	55	engineering	engineering	NOUN
admet-942	42	56	.	.	PUNCT
admet-942	43	1	this	this	DET
admet-942	43	2	complexity	complexity	NOUN
admet-942	43	3	of	of	ADP
admet-942	43	4	disciplines	discipline	NOUN
admet-942	43	5	allows	allow	VERB
admet-942	43	6	to	to	PART
admet-942	43	7	create	create	VERB
admet-942	43	8	microenvironments	microenvironment	NOUN
admet-942	43	9	with	with	ADP
admet-942	43	10	precise	precise	ADJ
admet-942	43	11	mechanical	mechanical	ADJ
admet-942	43	12	,	,	PUNCT
admet-942	43	13	and	and	CCONJ
admet-942	43	14	structural	structural	ADJ
admet-942	43	15	control	control	NOUN
admet-942	43	16	,	,	PUNCT
admet-942	43	17	providing	provide	VERB
admet-942	43	18	the	the	DET
admet-942	43	19	ability	ability	NOUN
admet-942	43	20	to	to	PART
admet-942	43	21	recreate	recreate	VERB
admet-942	43	22	concentration	concentration	NOUN
admet-942	43	23	gradients	gradient	NOUN
admet-942	43	24	,	,	PUNCT
admet-942	43	25	and	and	CCONJ
admet-942	43	26	nutrients	nutrient	NOUN
admet-942	43	27	and	and	CCONJ
admet-942	43	28	metabolites	metabolite	NOUN
admet-942	43	29	flows	flow	VERB
admet-942	43	30	[	[	X
admet-942	43	31	2,3,7,25–31	2,3,7,25–31	NUM
admet-942	43	32	]	]	X
admet-942	43	33	.	.	PUNCT
admet-942	44	1	therefore	therefore	ADV
admet-942	44	2	,	,	PUNCT
admet-942	44	3	they	they	PRON
admet-942	44	4	are	be	AUX
admet-942	44	5	versatile	versatile	ADJ
admet-942	44	6	and	and	CCONJ
admet-942	44	7	modifiable	modifiable	ADJ
admet-942	44	8	systems	system	NOUN
admet-942	44	9	with	with	ADP
admet-942	44	10	the	the	DET
admet-942	44	11	aim	aim	NOUN
admet-942	44	12	of	of	ADP
admet-942	44	13	showing	show	VERB
admet-942	44	14	an	an	DET
admet-942	44	15	adequate	adequate	ADJ
admet-942	44	16	histological	histological	ADJ
admet-942	44	17	composition	composition	NOUN
admet-942	44	18	that	that	PRON
admet-942	44	19	is	be	AUX
admet-942	44	20	suitable	suitable	ADJ
admet-942	44	21	for	for	ADP
admet-942	44	22	live	live	ADJ
admet-942	44	23	evaluation	evaluation	NOUN
admet-942	44	24	,	,	PUNCT
admet-942	44	25	which	which	PRON
admet-942	44	26	can	can	AUX
admet-942	44	27	not	not	PART
admet-942	44	28	be	be	AUX
admet-942	44	29	done	do	VERB
admet-942	44	30	by	by	ADP
admet-942	44	31	using	use	VERB
admet-942	44	32	animal	animal	NOUN
admet-942	44	33	models	model	NOUN
admet-942	44	34	[	[	X
admet-942	44	35	32	32	NUM
admet-942	44	36	]	]	PUNCT
admet-942	44	37	.	.	PUNCT
admet-942	45	1	as	as	ADP
admet-942	45	2	an	an	DET
admet-942	45	3	interdisciplinary	interdisciplinary	ADJ
admet-942	45	4	field	field	NOUN
admet-942	45	5	,	,	PUNCT
admet-942	45	6	a	a	DET
admet-942	45	7	broader	broad	ADJ
admet-942	45	8	understanding	understanding	NOUN
admet-942	45	9	of	of	ADP
admet-942	45	10	the	the	DET
admet-942	45	11	ooc	ooc	NOUN
admet-942	45	12	technology	technology	NOUN
admet-942	45	13	requires	require	VERB
admet-942	45	14	knowledge	knowledge	NOUN
admet-942	45	15	in	in	ADP
admet-942	45	16	each	each	PRON
admet-942	45	17	of	of	ADP
admet-942	45	18	the	the	DET
admet-942	45	19	sciences	science	NOUN
admet-942	45	20	that	that	PRON
admet-942	45	21	are	be	AUX
admet-942	45	22	part	part	NOUN
admet-942	45	23	of	of	ADP
admet-942	45	24	it	it	PRON
admet-942	45	25	.	.	PUNCT
admet-942	46	1	since	since	SCONJ
admet-942	46	2	the	the	DET
admet-942	46	3	evolution	evolution	NOUN
admet-942	46	4	of	of	ADP
admet-942	46	5	these	these	DET
admet-942	46	6	devices	device	NOUN
admet-942	46	7	involves	involve	VERB
admet-942	46	8	technology	technology	NOUN
admet-942	46	9	advances	advance	NOUN
admet-942	46	10	in	in	ADP
admet-942	46	11	each	each	PRON
admet-942	46	12	of	of	ADP
admet-942	46	13	these	these	DET
admet-942	46	14	areas	area	NOUN
admet-942	46	15	,	,	PUNCT
admet-942	46	16	it	it	PRON
admet-942	46	17	faces	face	VERB
admet-942	46	18	the	the	DET
admet-942	46	19	same	same	ADJ
admet-942	46	20	difficulties	difficulty	NOUN
admet-942	46	21	as	as	SCONJ
admet-942	46	22	they	they	PRON
admet-942	46	23	do	do	VERB
admet-942	46	24	[	[	X
admet-942	46	25	18	18	NUM
admet-942	46	26	]	]	X
admet-942	46	27	,	,	PUNCT
admet-942	46	28	especially	especially	ADV
admet-942	46	29	with	with	ADP
admet-942	46	30	the	the	DET
admet-942	46	31	objective	objective	NOUN
admet-942	46	32	of	of	ADP
admet-942	46	33	mass	mass	ADJ
admet-942	46	34	production	production	NOUN
admet-942	46	35	and	and	CCONJ
admet-942	46	36	sustainable	sustainable	ADJ
admet-942	46	37	implementation	implementation	NOUN
admet-942	46	38	of	of	ADP
admet-942	46	39	ooc	ooc	NOUN
admet-942	46	40	.	.	PUNCT
admet-942	47	1	some	some	PRON
admet-942	47	2	of	of	ADP
admet-942	47	3	these	these	DET
admet-942	47	4	challenges	challenge	NOUN
admet-942	47	5	are	be	AUX
admet-942	47	6	discussed	discuss	VERB
admet-942	47	7	later	later	ADV
admet-942	47	8	in	in	ADP
admet-942	47	9	this	this	DET
admet-942	47	10	document	document	NOUN
admet-942	47	11	,	,	PUNCT
admet-942	47	12	although	although	SCONJ
admet-942	47	13	the	the	DET
admet-942	47	14	authors	author	NOUN
admet-942	47	15	recommend	recommend	VERB
admet-942	47	16	a	a	DET
admet-942	47	17	further	further	ADJ
admet-942	47	18	study	study	NOUN
admet-942	47	19	of	of	ADP
admet-942	47	20	the	the	DET
admet-942	47	21	basic	basic	ADJ
admet-942	47	22	principles	principle	NOUN
admet-942	47	23	and	and	CCONJ
admet-942	47	24	state	state	NOUN
admet-942	47	25	of	of	ADP
admet-942	47	26	the	the	DET
admet-942	47	27	art	art	NOUN
admet-942	47	28	of	of	ADP
admet-942	47	29	the	the	DET
admet-942	47	30	abovementioned	abovementioned	ADJ
admet-942	47	31	scientific	scientific	ADJ
admet-942	47	32	fields	field	NOUN
admet-942	47	33	.	.	PUNCT
admet-942	48	1	detailed	detailed	ADJ
admet-942	48	2	reviews	review	NOUN
admet-942	48	3	focused	focus	VERB
admet-942	48	4	on	on	ADP
admet-942	48	5	each	each	PRON
admet-942	48	6	of	of	ADP
admet-942	48	7	these	these	DET
admet-942	48	8	research	research	NOUN
admet-942	48	9	areas	area	NOUN
admet-942	48	10	can	can	AUX
admet-942	48	11	be	be	AUX
admet-942	48	12	consulted	consult	VERB
admet-942	48	13	elsewhere	elsewhere	ADV
admet-942	48	14	[	[	X
admet-942	48	15	33–41	33–41	NUM
admet-942	48	16	]	]	PUNCT
admet-942	48	17	.	.	PUNCT
admet-942	49	1	the	the	DET
admet-942	49	2	spatial	spatial	ADJ
admet-942	49	3	configuration	configuration	NOUN
admet-942	49	4	of	of	ADP
admet-942	49	5	each	each	DET
admet-942	49	6	ooc	ooc	NOUN
admet-942	49	7	depends	depend	VERB
admet-942	49	8	on	on	ADP
admet-942	49	9	its	its	PRON
admet-942	49	10	design	design	NOUN
admet-942	49	11	and	and	CCONJ
admet-942	49	12	desired	desire	VERB
admet-942	49	13	function	function	NOUN
admet-942	49	14	,	,	PUNCT
admet-942	49	15	however	however	ADV
admet-942	49	16	,	,	PUNCT
admet-942	49	17	most	most	ADJ
admet-942	49	18	of	of	ADP
admet-942	49	19	them	they	PRON
admet-942	49	20	show	show	VERB
admet-942	49	21	the	the	DET
admet-942	49	22	general	general	ADJ
admet-942	49	23	outlines	outline	NOUN
admet-942	49	24	presented	present	VERB
admet-942	49	25	in	in	ADP
admet-942	49	26	figure	figure	NOUN
admet-942	49	27	1	1	NUM
admet-942	49	28	;	;	PUNCT
admet-942	49	29	they	they	PRON
admet-942	49	30	are	be	AUX
admet-942	49	31	constituted	constitute	VERB
admet-942	49	32	by	by	ADP
admet-942	49	33	a	a	DET
admet-942	49	34	physical	physical	ADJ
admet-942	49	35	compartment	compartment	NOUN
admet-942	49	36	for	for	ADP
admet-942	49	37	cell	cell	NOUN
admet-942	49	38	confinement	confinement	NOUN
admet-942	49	39	and	and	CCONJ
admet-942	49	40	several	several	ADJ
admet-942	49	41	microfluidic	microfluidic	ADJ
admet-942	49	42	channels	channel	NOUN
admet-942	49	43	,	,	PUNCT
admet-942	49	44	which	which	PRON
admet-942	49	45	are	be	AUX
admet-942	49	46	used	use	VERB
admet-942	49	47	for	for	ADP
admet-942	49	48	the	the	DET
admet-942	49	49	administration	administration	NOUN
admet-942	49	50	and	and	CCONJ
admet-942	49	51	transport	transport	NOUN
admet-942	49	52	of	of	ADP
admet-942	49	53	substances	substance	NOUN
admet-942	49	54	and	and	CCONJ
admet-942	49	55	measurable	measurable	ADJ
admet-942	49	56	signals	signal	NOUN
admet-942	49	57	.	.	PUNCT
admet-942	50	1	in	in	ADP
admet-942	50	2	their	their	PRON
admet-942	50	3	integrated	integrate	VERB
admet-942	50	4	compartment	compartment	NOUN
admet-942	50	5	oocs	ooc	NOUN
admet-942	50	6	allow	allow	VERB
admet-942	50	7	to	to	PART
admet-942	50	8	study	study	VERB
admet-942	50	9	,	,	PUNCT
admet-942	50	10	measure	measure	NOUN
admet-942	50	11	and	and	CCONJ
admet-942	50	12	control	control	NOUN
admet-942	50	13	cell	cell	NOUN
admet-942	50	14	behavior	behavior	NOUN
admet-942	50	15	,	,	PUNCT
admet-942	50	16	as	as	ADV
admet-942	50	17	well	well	ADV
admet-942	50	18	as	as	ADP
admet-942	50	19	the	the	DET
admet-942	50	20	response	response	NOUN
admet-942	50	21	of	of	ADP
admet-942	50	22	the	the	DET
admet-942	50	23	target	target	NOUN
admet-942	50	24	tissue	tissue	NOUN
admet-942	50	25	microenvironment	microenvironment	NOUN
admet-942	50	26	in	in	ADP
admet-942	50	27	front	front	NOUN
admet-942	50	28	of	of	ADP
admet-942	50	29	certain	certain	ADJ
admet-942	50	30	stimuli	stimulus	NOUN
admet-942	50	31	[	[	X
admet-942	50	32	2	2	NUM
admet-942	50	33	]	]	PUNCT
admet-942	50	34	.	.	PUNCT
admet-942	51	1	it	it	PRON
admet-942	51	2	is	be	AUX
admet-942	51	3	also	also	ADV
admet-942	51	4	possible	possible	ADJ
admet-942	51	5	to	to	PART
admet-942	51	6	integrate	integrate	VERB
admet-942	51	7	secondary	secondary	ADJ
admet-942	51	8	tissues	tissue	NOUN
admet-942	51	9	in	in	ADP
admet-942	51	10	the	the	DET
admet-942	51	11	ooc	ooc	NOUN
admet-942	51	12	,	,	PUNCT
admet-942	51	13	which	which	PRON
admet-942	51	14	can	can	AUX
admet-942	51	15	not	not	PART
admet-942	51	16	be	be	AUX
admet-942	51	17	performed	perform	VERB
admet-942	51	18	in	in	ADP
admet-942	51	19	traditional	traditional	ADJ
admet-942	51	20	cellular	cellular	ADJ
admet-942	51	21	models	model	NOUN
admet-942	51	22	[	[	X
admet-942	51	23	5	5	NUM
admet-942	51	24	]	]	PUNCT
admet-942	51	25	.	.	PUNCT
admet-942	52	1	the	the	DET
admet-942	52	2	ooc	ooc	NOUN
admet-942	52	3	can	can	AUX
admet-942	52	4	reproduce	reproduce	VERB
admet-942	52	5	particular	particular	ADJ
admet-942	52	6	conditions	condition	NOUN
admet-942	52	7	,	,	PUNCT
admet-942	52	8	such	such	ADJ
admet-942	52	9	as	as	ADP
admet-942	52	10	the	the	DET
admet-942	52	11	presence	presence	NOUN
admet-942	52	12	of	of	ADP
admet-942	52	13	specific	specific	ADJ
admet-942	52	14	pathologies	pathology	NOUN
admet-942	52	15	,	,	PUNCT
admet-942	52	16	age	age	NOUN
admet-942	52	17	and	and	CCONJ
admet-942	52	18	sex	sex	NOUN
admet-942	52	19	differences	difference	NOUN
admet-942	52	20	,	,	PUNCT
admet-942	52	21	or	or	CCONJ
admet-942	52	22	metabolic	metabolic	NOUN
admet-942	52	23	modifications	modification	NOUN
admet-942	52	24	[	[	X
admet-942	52	25	3,7,8,15,42–44	3,7,8,15,42–44	NOUN
admet-942	52	26	]	]	X
admet-942	52	27	.	.	PUNCT
admet-942	53	1	the	the	DET
admet-942	53	2	ability	ability	NOUN
admet-942	53	3	of	of	ADP
admet-942	53	4	ooc	ooc	NOUN
admet-942	53	5	systems	system	NOUN
admet-942	53	6	to	to	PART
admet-942	53	7	mimic	mimic	VERB
admet-942	53	8	the	the	DET
admet-942	53	9	functionality	functionality	NOUN
admet-942	53	10	of	of	ADP
admet-942	53	11	an	an	DET
admet-942	53	12	organ	organ	NOUN
admet-942	53	13	allows	allow	VERB
admet-942	53	14	to	to	PART
admet-942	53	15	visualize	visualize	VERB
admet-942	53	16	the	the	DET
admet-942	53	17	impact	impact	NOUN
admet-942	53	18	of	of	ADP
admet-942	53	19	a	a	DET
admet-942	53	20	condition	condition	NOUN
admet-942	53	21	on	on	ADP
admet-942	53	22	the	the	DET
admet-942	53	23	organ	organ	NOUN
admet-942	53	24	’s	’s	PART
admet-942	53	25	function	function	NOUN
admet-942	53	26	.	.	PUNCT
admet-942	54	1	for	for	ADP
admet-942	54	2	example	example	NOUN
admet-942	54	3	,	,	PUNCT
admet-942	54	4	for	for	ADP
admet-942	54	5	the	the	DET
admet-942	54	6	study	study	NOUN
admet-942	54	7	of	of	ADP
admet-942	54	8	a	a	DET
admet-942	54	9	viral	viral	ADJ
admet-942	54	10	infection	infection	NOUN
admet-942	54	11	at	at	ADP
admet-942	54	12	kidney	kidney	NOUN
admet-942	54	13	level	level	NOUN
admet-942	54	14	,	,	PUNCT
admet-942	54	15	a	a	DET
admet-942	54	16	traditional	traditional	ADJ
admet-942	54	17	2d	2d	NUM
admet-942	54	18	culture	culture	NOUN
admet-942	54	19	would	would	AUX
admet-942	54	20	be	be	AUX
admet-942	54	21	able	able	ADJ
admet-942	54	22	to	to	PART
admet-942	54	23	demonstrate	demonstrate	VERB
admet-942	54	24	the	the	DET
admet-942	54	25	virus	virus	NOUN
admet-942	54	26	replication	replication	NOUN
admet-942	54	27	but	but	CCONJ
admet-942	54	28	its	its	PRON
admet-942	54	29	impact	impact	NOUN
admet-942	54	30	on	on	ADP
admet-942	54	31	the	the	DET
admet-942	54	32	kidney	kidney	NOUN
admet-942	54	33	’s	’s	PART
admet-942	54	34	function	function	NOUN
admet-942	54	35	would	would	AUX
admet-942	54	36	not	not	PART
admet-942	54	37	be	be	AUX
admet-942	54	38	proved	prove	VERB
admet-942	54	39	unless	unless	SCONJ
admet-942	54	40	the	the	DET
admet-942	54	41	2d	2d	PROPN
admet-942	54	42	culture	culture	NOUN
admet-942	54	43	was	be	AUX
admet-942	54	44	coupled	couple	VERB
admet-942	54	45	to	to	ADP
admet-942	54	46	an	an	DET
admet-942	54	47	ooc	ooc	NOUN
admet-942	54	48	system	system	NOUN
admet-942	54	49	capable	capable	ADJ
admet-942	54	50	of	of	ADP
admet-942	54	51	mimicking	mimic	VERB
admet-942	54	52	glomerular	glomerular	ADJ
admet-942	54	53	filtration	filtration	NOUN
admet-942	55	1	[	[	X
admet-942	55	2	45	45	NUM
admet-942	55	3	]	]	PUNCT
admet-942	55	4	.	.	PUNCT
admet-942	56	1	figure	figure	NOUN
admet-942	56	2	1	1	NUM
admet-942	56	3	.	.	PUNCT
admet-942	57	1	examples	example	NOUN
admet-942	57	2	of	of	ADP
admet-942	57	3	ooc	ooc	NOUN
admet-942	57	4	devices	device	NOUN
admet-942	57	5	.	.	PUNCT
admet-942	58	1	a	a	DET
admet-942	58	2	)	)	PUNCT
admet-942	58	3	three	three	NUM
admet-942	58	4	-	-	PUNCT
admet-942	58	5	layer	layer	NOUN
admet-942	58	6	chip	chip	NOUN
admet-942	58	7	with	with	ADP
admet-942	58	8	a	a	DET
admet-942	58	9	cell	cell	NOUN
admet-942	58	10	culture	culture	NOUN
admet-942	58	11	receptacle	receptacle	NOUN
admet-942	58	12	on	on	ADP
admet-942	58	13	the	the	DET
admet-942	58	14	bottom	bottom	ADJ
admet-942	58	15	plate	plate	NOUN
admet-942	58	16	,	,	PUNCT
admet-942	58	17	and	and	CCONJ
admet-942	58	18	multiple	multiple	ADJ
admet-942	58	19	channel	channel	NOUN
admet-942	58	20	connectors	connector	NOUN
admet-942	58	21	for	for	ADP
admet-942	58	22	feed	feed	NOUN
admet-942	58	23	and	and	CCONJ
admet-942	58	24	signal	signal	VERB
admet-942	58	25	control	control	NOUN
admet-942	58	26	on	on	ADP
admet-942	58	27	the	the	DET
admet-942	58	28	top	top	ADJ
admet-942	58	29	plate	plate	NOUN
admet-942	58	30	.	.	PUNCT
admet-942	59	1	adapted	adapt	VERB
admet-942	59	2	from	from	ADP
admet-942	59	3	[	[	X
admet-942	59	4	46	46	NUM
admet-942	59	5	]	]	PUNCT
admet-942	59	6	with	with	ADP
admet-942	59	7	permission	permission	NOUN
admet-942	59	8	from	from	ADP
admet-942	59	9	the	the	DET
admet-942	59	10	royal	royal	ADJ
admet-942	59	11	society	society	NOUN
admet-942	59	12	of	of	ADP
admet-942	59	13	chemistry	chemistry	NOUN
admet-942	59	14	.	.	PUNCT
admet-942	60	1	copyright	copyright	NOUN
admet-942	60	2	(	(	PUNCT
admet-942	60	3	2018	2018	NUM
admet-942	60	4	)	)	PUNCT
admet-942	60	5	b	b	NOUN
admet-942	60	6	)	)	PUNCT
admet-942	60	7	a	a	DET
admet-942	60	8	two	two	NUM
admet-942	60	9	-	-	PUNCT
admet-942	60	10	channel	channel	NOUN
admet-942	60	11	ooc	ooc	NOUN
admet-942	60	12	for	for	ADP
admet-942	60	13	the	the	DET
admet-942	60	14	simulation	simulation	NOUN
admet-942	60	15	of	of	ADP
admet-942	60	16	an	an	DET
admet-942	60	17	epithelial	epithelial	ADJ
admet-942	60	18	tissue	tissue	NOUN
admet-942	60	19	.	.	PUNCT
admet-942	61	1	reproduced	reproduce	VERB
admet-942	61	2	from	from	ADP
admet-942	61	3	[	[	X
admet-942	61	4	47	47	NUM
admet-942	61	5	]	]	PUNCT
admet-942	61	6	under	under	ADP
admet-942	61	7	terms	term	NOUN
admet-942	61	8	of	of	ADP
admet-942	61	9	the	the	DET
admet-942	61	10	creative	creative	ADJ
admet-942	61	11	commons	common	NOUN
admet-942	61	12	attribution	attribution	NOUN
admet-942	61	13	license	license	NOUN
admet-942	61	14	.	.	PUNCT
admet-942	62	1	c	c	X
admet-942	62	2	)	)	PUNCT
admet-942	62	3	ooc	ooc	NOUN
admet-942	62	4	model	model	NOUN
admet-942	62	5	for	for	ADP
admet-942	62	6	the	the	DET
admet-942	62	7	simulation	simulation	NOUN
admet-942	62	8	of	of	ADP
admet-942	62	9	the	the	DET
admet-942	62	10	blood	blood	NOUN
admet-942	62	11	-	-	PUNCT
admet-942	62	12	brain	brain	NOUN
admet-942	62	13	barrier	barrier	NOUN
admet-942	62	14	with	with	ADP
admet-942	62	15	gel	gel	NOUN
admet-942	62	16	suspended	suspend	VERB
admet-942	62	17	astrocytes	astrocyte	NOUN
admet-942	62	18	and	and	CCONJ
admet-942	62	19	neurons	neuron	NOUN
admet-942	62	20	.	.	PUNCT
admet-942	63	1	reproduced	reproduce	VERB
admet-942	63	2	from	from	ADP
admet-942	63	3	[	[	X
admet-942	63	4	48	48	NUM
admet-942	63	5	]	]	PUNCT
admet-942	63	6	with	with	ADP
admet-942	63	7	permission	permission	NOUN
admet-942	63	8	from	from	ADP
admet-942	63	9	the	the	DET
admet-942	63	10	royal	royal	ADJ
admet-942	63	11	society	society	NOUN
admet-942	63	12	of	of	ADP
admet-942	63	13	chemistry	chemistry	NOUN
admet-942	63	14	.	.	PUNCT
admet-942	64	1	copyright	copyright	NOUN
admet-942	64	2	(	(	PUNCT
admet-942	64	3	2017	2017	NUM
admet-942	64	4	)	)	PUNCT
admet-942	64	5	.	.	PUNCT
admet-942	65	1	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	65	2	r.	r.	PROPN
admet-942	65	3	vargas	vargas	PROPN
admet-942	65	4	,	,	PUNCT
admet-942	65	5	a.	a.	NOUN
admet-942	65	6	egurbide	egurbide	NOUN
admet-942	65	7	-	-	PUNCT
admet-942	65	8	sifre	sifre	NOUN
admet-942	65	9	and	and	CCONJ
admet-942	65	10	l.	l.	PROPN
admet-942	65	11	medina	medina	PROPN
admet-942	65	12	admet	admet	PROPN
admet-942	65	13	&	&	CCONJ
admet-942	65	14	dmpk	dmpk	PROPN
admet-942	65	15	9(2	9(2	NUM
admet-942	65	16	)	)	PUNCT
admet-942	65	17	(	(	PUNCT
admet-942	65	18	2021	2021	NUM
admet-942	65	19	)	)	PUNCT
admet-942	65	20	111	111	NUM
admet-942	65	21	-	-	SYM
admet-942	65	22	141	141	NUM
admet-942	65	23	114	114	NUM
admet-942	65	24	ooc	ooc	NOUN
admet-942	65	25	systems	system	NOUN
admet-942	65	26	are	be	AUX
admet-942	65	27	intended	intend	VERB
admet-942	65	28	to	to	PART
admet-942	65	29	be	be	AUX
admet-942	65	30	a	a	DET
admet-942	65	31	useful	useful	ADJ
admet-942	65	32	tool	tool	NOUN
admet-942	65	33	to	to	PART
admet-942	65	34	reduce	reduce	VERB
admet-942	65	35	the	the	DET
admet-942	65	36	number	number	NOUN
admet-942	65	37	of	of	ADP
admet-942	65	38	false	false	ADJ
admet-942	65	39	positives	positive	NOUN
admet-942	65	40	and	and	CCONJ
admet-942	65	41	false	false	ADJ
admet-942	65	42	negatives	negative	NOUN
admet-942	65	43	in	in	ADP
admet-942	65	44	the	the	DET
admet-942	65	45	preclinical	preclinical	ADJ
admet-942	65	46	evaluation	evaluation	NOUN
admet-942	65	47	of	of	ADP
admet-942	65	48	potential	potential	ADJ
admet-942	65	49	drug	drug	NOUN
admet-942	65	50	prototypes	prototype	NOUN
admet-942	65	51	.	.	PUNCT
admet-942	66	1	therefore	therefore	ADV
admet-942	66	2	,	,	PUNCT
admet-942	66	3	they	they	PRON
admet-942	66	4	might	might	AUX
admet-942	66	5	be	be	AUX
admet-942	66	6	able	able	ADJ
admet-942	66	7	to	to	PART
admet-942	66	8	raise	raise	VERB
admet-942	66	9	the	the	DET
admet-942	66	10	number	number	NOUN
admet-942	66	11	of	of	ADP
admet-942	66	12	candidates	candidate	NOUN
admet-942	66	13	that	that	PRON
admet-942	66	14	successfully	successfully	ADV
admet-942	66	15	complete	complete	VERB
admet-942	66	16	clinical	clinical	ADJ
admet-942	66	17	trials	trial	NOUN
admet-942	66	18	[	[	X
admet-942	66	19	6	6	NUM
admet-942	66	20	]	]	PUNCT
admet-942	66	21	.	.	PUNCT
admet-942	67	1	moreover	moreover	ADV
admet-942	67	2	,	,	PUNCT
admet-942	67	3	these	these	DET
admet-942	67	4	systems	system	NOUN
admet-942	67	5	have	have	VERB
admet-942	67	6	fewer	few	ADJ
admet-942	67	7	ethical	ethical	ADJ
admet-942	67	8	or	or	CCONJ
admet-942	67	9	animal	animal	NOUN
admet-942	67	10	welfare	welfare	NOUN
admet-942	67	11	concerns	concern	NOUN
admet-942	67	12	than	than	ADP
admet-942	67	13	traditional	traditional	ADJ
admet-942	67	14	animal	animal	NOUN
admet-942	67	15	models	model	NOUN
admet-942	68	1	[	[	X
admet-942	68	2	49,50	49,50	X
admet-942	68	3	]	]	PUNCT
admet-942	68	4	.	.	PUNCT
admet-942	69	1	ooc	ooc	PROPN
admet-942	69	2	can	can	AUX
admet-942	69	3	facilitate	facilitate	VERB
admet-942	69	4	the	the	DET
admet-942	69	5	design	design	NOUN
admet-942	69	6	and	and	CCONJ
admet-942	69	7	validation	validation	NOUN
admet-942	69	8	of	of	ADP
admet-942	69	9	drugs	drug	NOUN
admet-942	69	10	that	that	PRON
admet-942	69	11	aim	aim	VERB
admet-942	69	12	specific	specific	ADJ
admet-942	69	13	cellular	cellular	ADJ
admet-942	69	14	and	and	CCONJ
admet-942	69	15	molecular	molecular	ADJ
admet-942	69	16	targets	target	NOUN
admet-942	69	17	[	[	X
admet-942	69	18	18,44	18,44	X
admet-942	69	19	]	]	X
admet-942	69	20	,	,	PUNCT
admet-942	69	21	and	and	CCONJ
admet-942	69	22	could	could	AUX
admet-942	69	23	be	be	AUX
admet-942	69	24	used	use	VERB
admet-942	69	25	to	to	PART
admet-942	69	26	establish	establish	VERB
admet-942	69	27	the	the	DET
admet-942	69	28	pharmacokinetic	pharmacokinetic	ADJ
admet-942	69	29	profile	profile	NOUN
admet-942	69	30	of	of	ADP
admet-942	69	31	drugs	drug	NOUN
admet-942	69	32	[	[	X
admet-942	69	33	51	51	NUM
admet-942	69	34	]	]	PUNCT
admet-942	69	35	.	.	PUNCT
admet-942	70	1	table	table	NOUN
admet-942	70	2	1	1	NUM
admet-942	70	3	shows	show	VERB
admet-942	70	4	some	some	PRON
admet-942	70	5	of	of	ADP
admet-942	70	6	the	the	DET
admet-942	70	7	main	main	ADJ
admet-942	70	8	characteristics	characteristic	NOUN
admet-942	70	9	of	of	ADP
admet-942	70	10	existing	exist	VERB
admet-942	70	11	preclinical	preclinical	ADJ
admet-942	70	12	models	model	NOUN
admet-942	70	13	for	for	ADP
admet-942	70	14	a	a	DET
admet-942	70	15	comparative	comparative	ADJ
admet-942	70	16	benefits	benefit	NOUN
admet-942	70	17	-	-	PUNCT
admet-942	70	18	drawbacks	drawback	NOUN
admet-942	70	19	evaluation	evaluation	NOUN
admet-942	70	20	.	.	PUNCT
admet-942	71	1	table	table	NOUN
admet-942	71	2	1	1	NUM
admet-942	71	3	.	.	PUNCT
admet-942	71	4	main	main	ADJ
admet-942	71	5	comparative	comparative	ADJ
admet-942	71	6	characteristics	characteristic	NOUN
admet-942	71	7	of	of	ADP
admet-942	71	8	traditional	traditional	ADJ
admet-942	71	9	preclinical	preclinical	ADJ
admet-942	71	10	evaluation	evaluation	NOUN
admet-942	71	11	models	model	NOUN
admet-942	71	12	and	and	CCONJ
admet-942	71	13	ooc	ooc	NOUN
admet-942	71	14	.	.	PUNCT
admet-942	72	1	modified	modify	VERB
admet-942	72	2	from	from	ADP
admet-942	72	3	[	[	X
admet-942	72	4	5	5	NUM
admet-942	72	5	]	]	PUNCT
admet-942	72	6	.	.	PUNCT
admet-942	73	1	characteristics	characteristics	PROPN
admet-942	73	2	animal	animal	NOUN
admet-942	73	3	2d	2d	NUM
admet-942	73	4	ooc	ooc	NOUN
admet-942	73	5	target	target	NOUN
admet-942	73	6	tissue	tissue	NOUN
admet-942	73	7	’s	’s	PART
admet-942	73	8	representativeness	representativeness	ADJ
admet-942	73	9	low	low	ADJ
admet-942	73	10	low	low	ADJ
admet-942	73	11	high	high	ADJ
admet-942	73	12	ethical	ethical	ADJ
admet-942	73	13	implications	implication	NOUN
admet-942	73	14	medium	medium	ADJ
admet-942	73	15	low	low	ADJ
admet-942	73	16	low	low	ADJ
admet-942	73	17	associated	associated	ADJ
admet-942	73	18	costs	cost	VERB
admet-942	73	19	high	high	ADJ
admet-942	73	20	low	low	ADJ
admet-942	73	21	low	low	ADJ
admet-942	73	22	viability	viability	NOUN
admet-942	73	23	maintenance	maintenance	NOUN
admet-942	73	24	medium	medium	ADJ
admet-942	73	25	high	high	ADJ
admet-942	73	26	high	high	ADJ
admet-942	73	27	high	high	ADJ
admet-942	73	28	throughput	throughput	NOUN
admet-942	73	29	analysis	analysis	NOUN
admet-942	73	30	aptitude	aptitude	NOUN
admet-942	73	31	low	low	ADJ
admet-942	73	32	high	high	ADJ
admet-942	73	33	medium	medium	ADJ
admet-942	73	34	full	full	ADJ
admet-942	73	35	body	body	NOUN
admet-942	73	36	representativeness	representativenes	VERB
admet-942	73	37	high	high	ADJ
admet-942	73	38	low	low	ADJ
admet-942	73	39	medium	medium	NOUN
admet-942	73	40	ooc	ooc	ADJ
admet-942	73	41	functional	functional	ADJ
admet-942	73	42	characteristics	characteristic	NOUN
admet-942	73	43	the	the	DET
admet-942	73	44	design	design	NOUN
admet-942	73	45	of	of	ADP
admet-942	73	46	ooc	ooc	PRON
admet-942	73	47	involves	involve	VERB
admet-942	73	48	reverse	reverse	ADJ
admet-942	73	49	engineering	engineering	NOUN
admet-942	73	50	of	of	ADP
admet-942	73	51	living	live	VERB
admet-942	73	52	organs	organ	NOUN
admet-942	73	53	[	[	X
admet-942	73	54	42,52	42,52	NOUN
admet-942	73	55	]	]	PUNCT
admet-942	73	56	,	,	PUNCT
admet-942	73	57	which	which	PRON
admet-942	73	58	requires	require	VERB
admet-942	73	59	an	an	DET
admet-942	73	60	in	in	ADP
admet-942	73	61	-	-	PUNCT
admet-942	73	62	depth	depth	NOUN
admet-942	73	63	study	study	NOUN
admet-942	73	64	of	of	ADP
admet-942	73	65	the	the	DET
admet-942	73	66	organs	organ	NOUN
admet-942	73	67	and	and	CCONJ
admet-942	73	68	their	their	PRON
admet-942	73	69	functions	function	NOUN
admet-942	73	70	to	to	PART
admet-942	73	71	develop	develop	VERB
admet-942	73	72	systems	system	NOUN
admet-942	73	73	more	more	ADV
admet-942	73	74	physiologically	physiologically	ADV
admet-942	73	75	relevant	relevant	ADJ
admet-942	73	76	than	than	ADP
admet-942	73	77	current	current	ADJ
admet-942	73	78	in	in	ADP
admet-942	73	79	vitro	vitro	X
admet-942	73	80	models	model	NOUN
admet-942	73	81	.	.	PUNCT
admet-942	74	1	this	this	PRON
admet-942	74	2	has	have	AUX
admet-942	74	3	promoted	promote	VERB
admet-942	74	4	the	the	DET
admet-942	74	5	physio	physio	ADJ
admet-942	74	6	-	-	PUNCT
admet-942	74	7	pathological	pathological	ADJ
admet-942	74	8	study	study	NOUN
admet-942	74	9	of	of	ADP
admet-942	74	10	multi	multi	ADJ
admet-942	74	11	-	-	ADJ
admet-942	74	12	organ	organ	ADJ
admet-942	74	13	interrelationships	interrelationship	NOUN
admet-942	74	14	[	[	X
admet-942	74	15	31,42,44,49,53	31,42,44,49,53	NUM
admet-942	74	16	]	]	PUNCT
admet-942	74	17	.	.	PUNCT
admet-942	75	1	the	the	DET
admet-942	75	2	main	main	ADJ
admet-942	75	3	benefits	benefit	NOUN
admet-942	75	4	of	of	ADP
admet-942	75	5	ooc	ooc	NOUN
admet-942	75	6	arise	arise	NOUN
admet-942	75	7	from	from	ADP
admet-942	75	8	their	their	PRON
admet-942	75	9	ability	ability	NOUN
admet-942	75	10	to	to	PART
admet-942	75	11	mimic	mimic	VERB
admet-942	75	12	three	three	NUM
admet-942	75	13	key	key	ADJ
admet-942	75	14	organ	organ	NOUN
admet-942	75	15	aspects	aspect	NOUN
admet-942	75	16	in	in	ADP
admet-942	75	17	their	their	PRON
admet-942	75	18	physiological	physiological	ADJ
admet-942	75	19	function	function	NOUN
admet-942	75	20	[	[	X
admet-942	75	21	7,54	7,54	X
admet-942	75	22	]	]	X
admet-942	75	23	,	,	PUNCT
admet-942	75	24	which	which	PRON
admet-942	75	25	are	be	AUX
admet-942	75	26	:	:	PUNCT
admet-942	75	27	1	1	X
admet-942	75	28	.	.	X
admet-942	75	29	interfaces	interface	NOUN
admet-942	75	30	that	that	PRON
admet-942	75	31	present	present	ADJ
admet-942	75	32	barrier	barrier	NOUN
admet-942	75	33	functions	function	NOUN
admet-942	75	34	composed	compose	VERB
admet-942	75	35	of	of	ADP
admet-942	75	36	multiple	multiple	ADJ
admet-942	75	37	tissues	tissue	NOUN
admet-942	75	38	and	and	CCONJ
admet-942	75	39	vasculature	vasculature	NOUN
admet-942	75	40	.	.	PUNCT
admet-942	76	1	2	2	X
admet-942	76	2	.	.	X
admet-942	76	3	organization	organization	NOUN
admet-942	76	4	at	at	ADP
admet-942	76	5	a	a	DET
admet-942	76	6	parenchymal	parenchymal	ADJ
admet-942	76	7	level	level	NOUN
admet-942	76	8	(	(	PUNCT
admet-942	76	9	i.e.	i.e.	X
admet-942	76	10	the	the	DET
admet-942	76	11	presence	presence	NOUN
admet-942	76	12	of	of	ADP
admet-942	76	13	different	different	ADJ
admet-942	76	14	tissue	tissue	NOUN
admet-942	76	15	substructures	substructure	NOUN
admet-942	76	16	within	within	ADP
admet-942	76	17	the	the	DET
admet-942	76	18	same	same	ADJ
admet-942	76	19	organ	organ	NOUN
admet-942	76	20	)	)	PUNCT
admet-942	76	21	.	.	PUNCT
admet-942	77	1	3	3	X
admet-942	77	2	.	.	X
admet-942	77	3	the	the	DET
admet-942	77	4	interaction	interaction	NOUN
admet-942	77	5	between	between	ADP
admet-942	77	6	different	different	ADJ
admet-942	77	7	organs	organ	NOUN
admet-942	77	8	.	.	PUNCT
admet-942	78	1	additionally	additionally	ADV
admet-942	78	2	,	,	PUNCT
admet-942	78	3	to	to	PART
admet-942	78	4	be	be	AUX
admet-942	78	5	adaptable	adaptable	ADJ
admet-942	78	6	to	to	ADP
admet-942	78	7	hts	hts	PROPN
admet-942	78	8	,	,	PUNCT
admet-942	78	9	ooc	ooc	PROPN
admet-942	78	10	systems	system	NOUN
admet-942	78	11	require	require	VERB
admet-942	78	12	the	the	DET
admet-942	78	13	incorporation	incorporation	NOUN
admet-942	78	14	of	of	ADP
admet-942	78	15	sensors	sensor	NOUN
admet-942	78	16	and	and	CCONJ
admet-942	78	17	communication	communication	NOUN
admet-942	78	18	channels	channel	NOUN
admet-942	78	19	[	[	X
admet-942	78	20	7,27,28	7,27,28	NUM
admet-942	78	21	]	]	PUNCT
admet-942	78	22	for	for	ADP
admet-942	78	23	real	real	ADJ
admet-942	78	24	-	-	PUNCT
admet-942	78	25	time	time	NOUN
admet-942	78	26	data	datum	NOUN
admet-942	78	27	collection	collection	NOUN
admet-942	78	28	and	and	CCONJ
admet-942	78	29	analysis	analysis	NOUN
admet-942	78	30	[	[	X
admet-942	78	31	42	42	NUM
admet-942	78	32	]	]	PUNCT
admet-942	78	33	.	.	PUNCT
admet-942	79	1	reproduction	reproduction	NOUN
admet-942	79	2	of	of	ADP
admet-942	79	3	barrier	barrier	NOUN
admet-942	79	4	or	or	CCONJ
admet-942	79	5	interface	interface	NOUN
admet-942	79	6	properties	property	NOUN
admet-942	79	7	non	non	ADJ
admet-942	79	8	-	-	ADJ
admet-942	79	9	homogeneous	homogeneous	ADJ
admet-942	79	10	cell	cell	NOUN
admet-942	79	11	mixtures	mixture	NOUN
admet-942	79	12	contain	contain	VERB
admet-942	79	13	variations	variation	NOUN
admet-942	79	14	in	in	ADP
admet-942	79	15	shape	shape	NOUN
admet-942	79	16	,	,	PUNCT
admet-942	79	17	arrangement	arrangement	NOUN
admet-942	79	18	and	and	CCONJ
admet-942	79	19	interaction	interaction	NOUN
admet-942	79	20	through	through	ADP
admet-942	79	21	interfaces	interface	NOUN
admet-942	79	22	of	of	ADP
admet-942	79	23	different	different	ADJ
admet-942	79	24	cells	cell	NOUN
admet-942	79	25	,	,	PUNCT
admet-942	79	26	which	which	PRON
admet-942	79	27	limits	limit	VERB
admet-942	79	28	the	the	DET
admet-942	79	29	use	use	NOUN
admet-942	79	30	of	of	ADP
admet-942	79	31	2d	2d	NUM
admet-942	79	32	cell	cell	NOUN
admet-942	79	33	cultures	culture	NOUN
admet-942	79	34	[	[	X
admet-942	79	35	7	7	NUM
admet-942	79	36	]	]	PUNCT
admet-942	79	37	.	.	PUNCT
admet-942	80	1	traditionally	traditionally	ADV
admet-942	80	2	,	,	PUNCT
admet-942	80	3	epithelia	epithelium	NOUN
admet-942	80	4	used	use	VERB
admet-942	80	5	to	to	PART
admet-942	80	6	be	be	AUX
admet-942	80	7	reproduced	reproduce	VERB
admet-942	80	8	in	in	ADP
admet-942	80	9	vitro	vitro	X
admet-942	80	10	as	as	ADP
admet-942	80	11	several	several	ADJ
admet-942	80	12	cell	cell	NOUN
admet-942	80	13	layers	layer	NOUN
admet-942	80	14	on	on	ADP
admet-942	80	15	a	a	DET
admet-942	80	16	surface	surface	NOUN
admet-942	80	17	.	.	PUNCT
admet-942	81	1	however	however	ADV
admet-942	81	2	,	,	PUNCT
admet-942	81	3	the	the	DET
admet-942	81	4	evolution	evolution	NOUN
admet-942	81	5	of	of	ADP
admet-942	81	6	ooc	ooc	NOUN
admet-942	81	7	production	production	NOUN
admet-942	81	8	systems	system	NOUN
admet-942	81	9	,	,	PUNCT
admet-942	81	10	and	and	CCONJ
admet-942	81	11	the	the	DET
admet-942	81	12	ability	ability	NOUN
admet-942	81	13	to	to	PART
admet-942	81	14	diversify	diversify	VERB
admet-942	81	15	3d	3d	NUM
admet-942	81	16	structures	structure	NOUN
admet-942	81	17	,	,	PUNCT
admet-942	81	18	allow	allow	VERB
admet-942	81	19	a	a	DET
admet-942	81	20	more	more	ADV
admet-942	81	21	accurate	accurate	ADJ
admet-942	81	22	correspondence	correspondence	NOUN
admet-942	81	23	with	with	ADP
admet-942	81	24	the	the	DET
admet-942	81	25	physiological	physiological	ADJ
admet-942	81	26	and	and	CCONJ
admet-942	81	27	anatomic	anatomic	ADJ
admet-942	81	28	-	-	PUNCT
admet-942	81	29	functional	functional	ADJ
admet-942	81	30	conditions	condition	NOUN
admet-942	81	31	of	of	ADP
admet-942	81	32	epithelial	epithelial	ADJ
admet-942	81	33	barriers	barrier	NOUN
admet-942	81	34	[	[	X
admet-942	81	35	47	47	NUM
admet-942	81	36	]	]	PUNCT
admet-942	81	37	.	.	PUNCT
admet-942	82	1	ooc	ooc	PRON
admet-942	82	2	microfluidic	microfluidic	ADJ
admet-942	82	3	channels	channel	NOUN
admet-942	82	4	can	can	AUX
admet-942	82	5	incorporate	incorporate	VERB
admet-942	82	6	polymeric	polymeric	ADJ
admet-942	82	7	membranes	membrane	NOUN
admet-942	82	8	to	to	PART
admet-942	82	9	model	model	VERB
admet-942	82	10	tissue	tissue	NOUN
admet-942	82	11	interfaces	interface	NOUN
admet-942	82	12	,	,	PUNCT
admet-942	82	13	simulate	simulate	VERB
admet-942	82	14	barrier	barrier	NOUN
admet-942	82	15	properties	property	NOUN
admet-942	82	16	and	and	CCONJ
admet-942	82	17	,	,	PUNCT
admet-942	82	18	in	in	ADP
admet-942	82	19	some	some	DET
admet-942	82	20	cases	case	NOUN
admet-942	82	21	,	,	PUNCT
admet-942	82	22	they	they	PRON
admet-942	82	23	can	can	AUX
admet-942	82	24	even	even	ADV
admet-942	82	25	include	include	VERB
admet-942	82	26	programmed	program	VERB
admet-942	82	27	mechanical	mechanical	ADJ
admet-942	82	28	instruments	instrument	NOUN
admet-942	83	1	[	[	X
admet-942	83	2	7,50,55	7,50,55	NUM
admet-942	83	3	]	]	PUNCT
admet-942	83	4	.	.	PUNCT
admet-942	84	1	the	the	DET
admet-942	84	2	possibility	possibility	NOUN
admet-942	84	3	of	of	ADP
admet-942	84	4	establishing	establish	VERB
admet-942	84	5	a	a	DET
admet-942	84	6	3d	3d	NUM
admet-942	84	7	vascular	vascular	ADJ
admet-942	84	8	structure	structure	NOUN
admet-942	84	9	enables	enable	VERB
admet-942	84	10	to	to	PART
admet-942	84	11	extend	extend	VERB
admet-942	84	12	the	the	DET
admet-942	84	13	complexity	complexity	NOUN
admet-942	84	14	and	and	CCONJ
admet-942	84	15	representativeness	representativeness	NOUN
admet-942	84	16	of	of	ADP
admet-942	84	17	the	the	DET
admet-942	84	18	systems	system	NOUN
admet-942	84	19	mimicked	mimic	VERB
admet-942	84	20	in	in	ADP
admet-942	84	21	an	an	DET
admet-942	84	22	ooc	ooc	NOUN
admet-942	84	23	.	.	PUNCT
admet-942	85	1	this	this	PRON
admet-942	85	2	is	be	AUX
admet-942	85	3	especially	especially	ADV
admet-942	85	4	valuable	valuable	ADJ
admet-942	85	5	with	with	ADP
admet-942	85	6	regard	regard	NOUN
admet-942	85	7	to	to	ADP
admet-942	85	8	the	the	DET
admet-942	85	9	targeting	targeting	NOUN
admet-942	85	10	of	of	ADP
admet-942	85	11	nutrients	nutrient	NOUN
admet-942	85	12	and	and	CCONJ
admet-942	85	13	exogenous	exogenous	ADJ
admet-942	85	14	substances	substance	NOUN
admet-942	85	15	if	if	SCONJ
admet-942	85	16	compared	compare	VERB
admet-942	85	17	to	to	ADP
admet-942	85	18	2d	2d	NUM
admet-942	85	19	tissues	tissue	NOUN
admet-942	85	20	,	,	PUNCT
admet-942	85	21	where	where	SCONJ
admet-942	85	22	transport	transport	NOUN
admet-942	85	23	occurs	occur	VERB
admet-942	85	24	by	by	ADP
admet-942	85	25	simple	simple	ADJ
admet-942	85	26	diffusion	diffusion	NOUN
admet-942	85	27	[	[	X
admet-942	85	28	55	55	NUM
admet-942	85	29	]	]	PUNCT
admet-942	85	30	.	.	PUNCT
admet-942	86	1	furthermore	furthermore	ADV
admet-942	86	2	,	,	PUNCT
admet-942	86	3	oocs	ooc	NOUN
admet-942	86	4	have	have	VERB
admet-942	86	5	the	the	DET
admet-942	86	6	ability	ability	NOUN
admet-942	86	7	to	to	PART
admet-942	86	8	include	include	VERB
admet-942	86	9	dynamic	dynamic	ADJ
admet-942	86	10	factors	factor	NOUN
admet-942	86	11	that	that	PRON
admet-942	86	12	simulate	simulate	VERB
admet-942	86	13	complex	complex	ADJ
admet-942	86	14	biological	biological	ADJ
admet-942	86	15	events	event	NOUN
admet-942	87	1	[	[	X
admet-942	87	2	7,56	7,56	X
admet-942	87	3	]	]	PUNCT
admet-942	87	4	.	.	PUNCT
admet-942	88	1	on	on	ADP
admet-942	88	2	one	one	NUM
admet-942	88	3	hand	hand	NOUN
admet-942	88	4	,	,	PUNCT
admet-942	88	5	the	the	DET
admet-942	88	6	simulation	simulation	NOUN
admet-942	88	7	of	of	ADP
admet-942	88	8	the	the	DET
admet-942	88	9	physiological	physiological	ADJ
admet-942	88	10	interface	interface	NOUN
admet-942	88	11	can	can	AUX
admet-942	88	12	be	be	AUX
admet-942	88	13	performed	perform	VERB
admet-942	88	14	in	in	ADP
admet-942	88	15	the	the	DET
admet-942	88	16	chip	chip	NOUN
admet-942	88	17	’s	’s	PART
admet-942	88	18	primary	primary	ADJ
admet-942	88	19	admet	admet	PROPN
admet-942	88	20	&	&	CCONJ
admet-942	88	21	dmpk	dmpk	PROPN
admet-942	88	22	9(2	9(2	NUM
admet-942	88	23	)	)	PUNCT
admet-942	88	24	(	(	PUNCT
admet-942	88	25	2021	2021	NUM
admet-942	88	26	)	)	PUNCT
admet-942	88	27	111	111	NUM
admet-942	88	28	-	-	SYM
admet-942	88	29	141	141	NUM
admet-942	88	30	organ	organ	NOUN
admet-942	88	31	-	-	PUNCT
admet-942	88	32	on	on	ADP
admet-942	88	33	-	-	PUNCT
admet-942	88	34	a	a	DET
admet-942	88	35	-	-	PUNCT
admet-942	88	36	chip	chip	NOUN
admet-942	88	37	systems	system	NOUN
admet-942	88	38	for	for	ADP
admet-942	88	39	new	new	ADJ
admet-942	88	40	drugs	drug	NOUN
admet-942	88	41	development	development	NOUN
admet-942	88	42	doi	doi	PROPN
admet-942	88	43	:	:	PUNCT
admet-942	88	44	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	NOUN
admet-942	88	45	115	115	NUM
admet-942	88	46	physical	physical	ADJ
admet-942	88	47	structure	structure	NOUN
admet-942	88	48	itself	itself	PRON
admet-942	88	49	or	or	CCONJ
admet-942	88	50	by	by	ADP
admet-942	88	51	controlling	control	VERB
admet-942	88	52	the	the	DET
admet-942	88	53	mobility	mobility	NOUN
admet-942	88	54	of	of	ADP
admet-942	88	55	hydrogels	hydrogel	NOUN
admet-942	88	56	through	through	ADP
admet-942	88	57	the	the	DET
admet-942	88	58	channels	channel	NOUN
admet-942	88	59	of	of	ADP
admet-942	88	60	this	this	DET
admet-942	88	61	polymeric	polymeric	ADJ
admet-942	88	62	structure	structure	NOUN
admet-942	88	63	[	[	X
admet-942	88	64	7	7	NUM
admet-942	88	65	]	]	PUNCT
admet-942	88	66	.	.	PUNCT
admet-942	89	1	current	current	ADJ
admet-942	89	2	printing	printing	NOUN
admet-942	89	3	techniques	technique	NOUN
admet-942	89	4	allow	allow	VERB
admet-942	89	5	complex	complex	ADJ
admet-942	89	6	3d	3d	NUM
admet-942	89	7	structures	structure	NOUN
admet-942	89	8	to	to	PART
admet-942	89	9	simulate	simulate	VERB
admet-942	89	10	vascularized	vascularized	ADJ
admet-942	89	11	tissues	tissue	NOUN
admet-942	89	12	and	and	CCONJ
admet-942	89	13	to	to	PART
admet-942	89	14	modulate	modulate	VERB
admet-942	89	15	permeability	permeability	NOUN
admet-942	89	16	through	through	ADP
admet-942	89	17	the	the	DET
admet-942	89	18	creation	creation	NOUN
admet-942	89	19	of	of	ADP
admet-942	89	20	nano	nano	NOUN
admet-942	89	21	-	-	PUNCT
admet-942	89	22	porosities	porosity	NOUN
admet-942	89	23	[	[	X
admet-942	89	24	7,42,57,58	7,42,57,58	NUM
admet-942	89	25	]	]	PUNCT
admet-942	89	26	.	.	PUNCT
admet-942	90	1	therefore	therefore	ADV
admet-942	90	2	,	,	PUNCT
admet-942	90	3	it	it	PRON
admet-942	90	4	is	be	AUX
admet-942	90	5	possible	possible	ADJ
admet-942	90	6	to	to	PART
admet-942	90	7	provide	provide	VERB
admet-942	90	8	mechanical	mechanical	ADJ
admet-942	90	9	stability	stability	NOUN
admet-942	90	10	to	to	ADP
admet-942	90	11	functional	functional	ADJ
admet-942	90	12	cell	cell	NOUN
admet-942	90	13	cultures	culture	NOUN
admet-942	90	14	and	and	CCONJ
admet-942	90	15	to	to	PART
admet-942	90	16	generate	generate	VERB
admet-942	90	17	a	a	DET
admet-942	90	18	network	network	NOUN
admet-942	90	19	designed	design	VERB
admet-942	90	20	for	for	ADP
admet-942	90	21	the	the	DET
admet-942	90	22	transport	transport	NOUN
admet-942	90	23	of	of	ADP
admet-942	90	24	substances	substance	NOUN
admet-942	90	25	and	and	CCONJ
admet-942	90	26	to	to	PART
admet-942	90	27	simulate	simulate	VERB
admet-942	90	28	specific	specific	ADJ
admet-942	90	29	desired	desire	VERB
admet-942	90	30	(	(	PUNCT
admet-942	90	31	even	even	ADV
admet-942	90	32	pathogenic	pathogenic	ADJ
admet-942	90	33	)	)	PUNCT
admet-942	90	34	organ	organ	NOUN
admet-942	90	35	-	-	PUNCT
admet-942	90	36	organ	organ	NOUN
admet-942	90	37	interaction	interaction	NOUN
admet-942	90	38	conditions	condition	NOUN
admet-942	90	39	[	[	X
admet-942	90	40	7,26	7,26	NOUN
admet-942	90	41	]	]	PUNCT
admet-942	90	42	.	.	PUNCT
admet-942	91	1	on	on	ADP
admet-942	91	2	the	the	DET
admet-942	91	3	other	other	ADJ
admet-942	91	4	hand	hand	NOUN
admet-942	91	5	,	,	PUNCT
admet-942	91	6	the	the	DET
admet-942	91	7	use	use	NOUN
admet-942	91	8	of	of	ADP
admet-942	91	9	hydrogels	hydrogel	NOUN
admet-942	91	10	(	(	PUNCT
admet-942	91	11	e.g.	e.g.	ADV
admet-942	91	12	gelatine	gelatine	NOUN
admet-942	91	13	,	,	PUNCT
admet-942	91	14	fibrin	fibrin	NOUN
admet-942	91	15	or	or	CCONJ
admet-942	91	16	collagen	collagen	NOUN
admet-942	91	17	)	)	PUNCT
admet-942	91	18	within	within	ADP
admet-942	91	19	the	the	DET
admet-942	91	20	chip	chip	NOUN
admet-942	91	21	channels	channel	NOUN
admet-942	91	22	generates	generate	VERB
admet-942	91	23	hydrophilic	hydrophilic	ADJ
admet-942	91	24	networks	network	NOUN
admet-942	91	25	that	that	PRON
admet-942	91	26	provide	provide	VERB
admet-942	91	27	the	the	DET
admet-942	91	28	system	system	NOUN
admet-942	91	29	with	with	ADP
admet-942	91	30	slight	slight	ADJ
admet-942	91	31	selective	selective	ADJ
admet-942	91	32	permeability	permeability	NOUN
admet-942	91	33	[	[	X
admet-942	91	34	43,59,60	43,59,60	NUM
admet-942	91	35	]	]	PUNCT
admet-942	91	36	.	.	PUNCT
admet-942	92	1	the	the	DET
admet-942	92	2	mimicking	mimicking	NOUN
admet-942	92	3	of	of	ADP
admet-942	92	4	several	several	ADJ
admet-942	92	5	epithelial	epithelial	ADJ
admet-942	92	6	structures	structure	NOUN
admet-942	92	7	such	such	ADJ
admet-942	92	8	as	as	ADP
admet-942	92	9	blood	blood	NOUN
admet-942	92	10	vessels	vessel	NOUN
admet-942	92	11	,	,	PUNCT
admet-942	92	12	alveoli	alveoli	PRON
admet-942	92	13	and	and	CCONJ
admet-942	92	14	the	the	DET
admet-942	92	15	blood	blood	NOUN
admet-942	92	16	-	-	PUNCT
admet-942	92	17	brain	brain	NOUN
admet-942	92	18	barrier	barrier	NOUN
admet-942	92	19	have	have	AUX
admet-942	92	20	been	be	AUX
admet-942	92	21	achieved	achieve	VERB
admet-942	92	22	by	by	ADP
admet-942	92	23	using	use	VERB
admet-942	92	24	oocs	ooc	NOUN
admet-942	92	25	[	[	X
admet-942	92	26	61	61	NUM
admet-942	92	27	]	]	PUNCT
admet-942	92	28	.	.	PUNCT
admet-942	93	1	reproduction	reproduction	NOUN
admet-942	93	2	of	of	ADP
admet-942	93	3	parenchymal	parenchymal	ADJ
admet-942	93	4	tissue	tissue	NOUN
admet-942	93	5	in	in	ADP
admet-942	93	6	a	a	DET
admet-942	93	7	living	live	VERB
admet-942	93	8	organism	organism	NOUN
admet-942	93	9	,	,	PUNCT
admet-942	93	10	cells	cell	NOUN
admet-942	93	11	are	be	AUX
admet-942	93	12	specifically	specifically	ADV
admet-942	93	13	organized	organize	VERB
admet-942	93	14	according	accord	VERB
admet-942	93	15	to	to	ADP
admet-942	93	16	tissue	tissue	NOUN
admet-942	93	17	’s	’s	PART
admet-942	93	18	function	function	NOUN
admet-942	94	1	[	[	X
admet-942	94	2	2,7,43,62	2,7,43,62	NOUN
admet-942	94	3	]	]	PUNCT
admet-942	94	4	.	.	PUNCT
admet-942	95	1	the	the	DET
admet-942	95	2	arrangement	arrangement	NOUN
admet-942	95	3	of	of	ADP
admet-942	95	4	these	these	DET
admet-942	95	5	cells	cell	NOUN
admet-942	95	6	is	be	AUX
admet-942	95	7	one	one	NUM
admet-942	95	8	of	of	ADP
admet-942	95	9	the	the	DET
admet-942	95	10	main	main	ADJ
admet-942	95	11	features	feature	NOUN
admet-942	95	12	to	to	PART
admet-942	95	13	consider	consider	VERB
admet-942	95	14	for	for	ADP
admet-942	95	15	the	the	DET
admet-942	95	16	physiological	physiological	ADJ
admet-942	95	17	simulation	simulation	NOUN
admet-942	95	18	outside	outside	ADP
admet-942	95	19	the	the	DET
admet-942	95	20	native	native	ADJ
admet-942	95	21	environment	environment	NOUN
admet-942	95	22	[	[	X
admet-942	95	23	8,31,42,63	8,31,42,63	NUM
admet-942	95	24	]	]	PUNCT
admet-942	95	25	.	.	PUNCT
admet-942	96	1	while	while	SCONJ
admet-942	96	2	membranes	membrane	NOUN
admet-942	96	3	and	and	CCONJ
admet-942	96	4	barriers	barrier	NOUN
admet-942	96	5	can	can	AUX
admet-942	96	6	be	be	AUX
admet-942	96	7	simulated	simulate	VERB
admet-942	96	8	in	in	ADP
admet-942	96	9	both	both	PRON
admet-942	96	10	2d	2d	NOUN
admet-942	96	11	and	and	CCONJ
admet-942	96	12	3d	3d	NUM
admet-942	96	13	cultures	culture	NOUN
admet-942	96	14	,	,	PUNCT
admet-942	96	15	complex	complex	ADJ
admet-942	96	16	parenchymal	parenchymal	ADJ
admet-942	96	17	structures	structure	NOUN
admet-942	96	18	can	can	AUX
admet-942	96	19	not	not	PART
admet-942	96	20	be	be	AUX
admet-942	96	21	mimicked	mimic	VERB
admet-942	96	22	in	in	ADP
admet-942	96	23	a	a	DET
admet-942	96	24	2d	2d	NUM
admet-942	96	25	culture	culture	NOUN
admet-942	96	26	[	[	X
admet-942	96	27	1,7,8,28,43,63	1,7,8,28,43,63	NUM
admet-942	96	28	]	]	PUNCT
admet-942	96	29	.	.	PUNCT
admet-942	97	1	furthermore	furthermore	ADV
admet-942	97	2	,	,	PUNCT
admet-942	97	3	gene	gene	NOUN
admet-942	97	4	expression	expression	NOUN
admet-942	97	5	of	of	ADP
admet-942	97	6	cells	cell	NOUN
admet-942	97	7	has	have	AUX
admet-942	97	8	been	be	AUX
admet-942	97	9	observed	observe	VERB
admet-942	97	10	to	to	PART
admet-942	97	11	be	be	AUX
admet-942	97	12	greater	great	ADJ
admet-942	97	13	in	in	ADP
admet-942	97	14	3d	3d	PROPN
admet-942	97	15	tissues	tissue	NOUN
admet-942	97	16	compared	compare	VERB
admet-942	97	17	to	to	ADP
admet-942	97	18	2d	2d	NUM
admet-942	97	19	cell	cell	NOUN
admet-942	97	20	cultures	culture	NOUN
admet-942	97	21	[	[	X
admet-942	97	22	64	64	NUM
admet-942	97	23	]	]	PUNCT
admet-942	97	24	.	.	PUNCT
admet-942	98	1	considering	consider	VERB
admet-942	98	2	two	two	NUM
admet-942	98	3	models	model	NOUN
admet-942	98	4	of	of	ADP
admet-942	98	5	cardiotoxicity	cardiotoxicity	NOUN
admet-942	98	6	assessment	assessment	NOUN
admet-942	98	7	,	,	PUNCT
admet-942	98	8	an	an	DET
admet-942	98	9	in	in	ADP
admet-942	98	10	vitro	vitro	X
admet-942	98	11	2d	2d	NUM
admet-942	98	12	model	model	NOUN
admet-942	98	13	enables	enable	VERB
admet-942	98	14	the	the	DET
admet-942	98	15	evaluation	evaluation	NOUN
admet-942	98	16	of	of	ADP
admet-942	98	17	the	the	DET
admet-942	98	18	cardiomyocytes	cardiomyocyte	NOUN
admet-942	98	19	viability	viability	NOUN
admet-942	98	20	in	in	ADP
admet-942	98	21	the	the	DET
admet-942	98	22	presence	presence	NOUN
admet-942	98	23	of	of	ADP
admet-942	98	24	a	a	DET
admet-942	98	25	drug	drug	NOUN
admet-942	98	26	but	but	CCONJ
admet-942	98	27	it	it	PRON
admet-942	98	28	can	can	AUX
admet-942	98	29	not	not	PART
admet-942	98	30	assess	assess	VERB
admet-942	98	31	the	the	DET
admet-942	98	32	functionality	functionality	NOUN
admet-942	98	33	of	of	ADP
admet-942	98	34	the	the	DET
admet-942	98	35	cells	cell	NOUN
admet-942	98	36	.	.	PUNCT
admet-942	99	1	nevertheless	nevertheless	ADV
admet-942	99	2	,	,	PUNCT
admet-942	99	3	the	the	DET
admet-942	99	4	effect	effect	NOUN
admet-942	99	5	that	that	SCONJ
admet-942	99	6	this	this	DET
admet-942	99	7	drug	drug	NOUN
admet-942	99	8	may	may	AUX
admet-942	99	9	produce	produce	VERB
admet-942	99	10	in	in	ADP
admet-942	99	11	the	the	DET
admet-942	99	12	contraction	contraction	NOUN
admet-942	99	13	capacity	capacity	NOUN
admet-942	99	14	of	of	ADP
admet-942	99	15	cardiomyocytes	cardiomyocyte	NOUN
admet-942	99	16	could	could	AUX
admet-942	99	17	be	be	AUX
admet-942	99	18	observed	observe	VERB
admet-942	99	19	by	by	ADP
admet-942	99	20	using	use	VERB
admet-942	99	21	a	a	DET
admet-942	99	22	3d	3d	NUM
admet-942	99	23	arrangement	arrangement	NOUN
admet-942	99	24	.	.	PUNCT
admet-942	100	1	an	an	DET
admet-942	100	2	adverse	adverse	ADJ
admet-942	100	3	reaction	reaction	NOUN
admet-942	100	4	,	,	PUNCT
admet-942	100	5	such	such	ADJ
admet-942	100	6	as	as	ADP
admet-942	100	7	arrhythmia	arrhythmia	NOUN
admet-942	100	8	,	,	PUNCT
admet-942	100	9	might	might	AUX
admet-942	100	10	not	not	PART
admet-942	100	11	be	be	AUX
admet-942	100	12	detected	detect	VERB
admet-942	100	13	in	in	ADP
admet-942	100	14	the	the	DET
admet-942	100	15	2d	2d	NUM
admet-942	100	16	model	model	NOUN
admet-942	100	17	and	and	CCONJ
admet-942	100	18	would	would	AUX
admet-942	100	19	become	become	VERB
admet-942	100	20	a	a	DET
admet-942	100	21	potential	potential	ADJ
admet-942	100	22	issue	issue	NOUN
admet-942	100	23	on	on	ADP
admet-942	100	24	further	further	ADJ
admet-942	100	25	clinical	clinical	ADJ
admet-942	100	26	phases	phase	NOUN
admet-942	100	27	,	,	PUNCT
admet-942	100	28	but	but	CCONJ
admet-942	100	29	it	it	PRON
admet-942	100	30	could	could	AUX
admet-942	100	31	be	be	AUX
admet-942	100	32	noticed	notice	VERB
admet-942	100	33	employing	employ	VERB
admet-942	100	34	an	an	DET
admet-942	100	35	ooc	ooc	NOUN
admet-942	100	36	that	that	PRON
admet-942	100	37	evaluates	evaluate	VERB
admet-942	100	38	changes	change	NOUN
admet-942	100	39	in	in	ADP
admet-942	100	40	the	the	DET
admet-942	100	41	3d	3d	NUM
admet-942	100	42	accommodation	accommodation	NOUN
admet-942	100	43	and	and	CCONJ
admet-942	100	44	the	the	DET
admet-942	100	45	proper	proper	ADJ
admet-942	100	46	functionality	functionality	NOUN
admet-942	100	47	of	of	ADP
admet-942	100	48	the	the	DET
admet-942	100	49	organ	organ	NOUN
admet-942	101	1	[	[	X
admet-942	101	2	44,65	44,65	NOUN
admet-942	101	3	]	]	PUNCT
admet-942	101	4	.	.	PUNCT
admet-942	102	1	reproduction	reproduction	NOUN
admet-942	102	2	of	of	ADP
admet-942	102	3	the	the	DET
admet-942	102	4	interaction	interaction	NOUN
admet-942	102	5	between	between	ADP
admet-942	102	6	organs	organ	NOUN
admet-942	102	7	living	live	VERB
admet-942	102	8	tissues	tissue	NOUN
admet-942	102	9	are	be	AUX
admet-942	102	10	highly	highly	ADV
admet-942	102	11	integrated	integrate	VERB
admet-942	102	12	,	,	PUNCT
admet-942	102	13	they	they	PRON
admet-942	102	14	are	be	AUX
admet-942	102	15	not	not	PART
admet-942	102	16	isolated	isolate	VERB
admet-942	102	17	,	,	PUNCT
admet-942	102	18	in	in	ADP
admet-942	102	19	such	such	DET
admet-942	102	20	a	a	DET
admet-942	102	21	way	way	NOUN
admet-942	102	22	that	that	PRON
admet-942	102	23	the	the	DET
admet-942	102	24	effects	effect	NOUN
admet-942	102	25	in	in	ADP
admet-942	102	26	one	one	NUM
admet-942	102	27	tissue	tissue	NOUN
admet-942	102	28	can	can	AUX
admet-942	102	29	impact	impact	VERB
admet-942	102	30	other	other	ADJ
admet-942	102	31	tissues	tissue	NOUN
admet-942	102	32	[	[	X
admet-942	102	33	66	66	NUM
admet-942	102	34	]	]	PUNCT
admet-942	102	35	.	.	PUNCT
admet-942	103	1	intercommunication	intercommunication	NOUN
admet-942	103	2	between	between	ADP
admet-942	103	3	different	different	ADJ
admet-942	103	4	organs	organ	NOUN
admet-942	103	5	plays	play	VERB
admet-942	103	6	an	an	DET
admet-942	103	7	important	important	ADJ
admet-942	103	8	role	role	NOUN
admet-942	103	9	in	in	ADP
admet-942	103	10	the	the	DET
admet-942	103	11	safety	safety	NOUN
admet-942	103	12	of	of	ADP
admet-942	103	13	a	a	DET
admet-942	103	14	drug	drug	NOUN
admet-942	103	15	and	and	CCONJ
admet-942	103	16	,	,	PUNCT
admet-942	103	17	thus	thus	ADV
admet-942	103	18	,	,	PUNCT
admet-942	103	19	in	in	ADP
admet-942	103	20	the	the	DET
admet-942	103	21	cost	cost	NOUN
admet-942	103	22	-	-	PUNCT
admet-942	103	23	benefit	benefit	NOUN
admet-942	103	24	ratio	ratio	NOUN
admet-942	103	25	of	of	ADP
admet-942	103	26	the	the	DET
admet-942	103	27	clinical	clinical	ADJ
admet-942	103	28	studies	study	NOUN
admet-942	103	29	[	[	X
admet-942	103	30	42	42	NUM
admet-942	103	31	]	]	PUNCT
admet-942	103	32	.	.	PUNCT
admet-942	104	1	this	this	DET
admet-942	104	2	inter	inter	ADJ
admet-942	104	3	-	-	ADJ
admet-942	104	4	organ	organ	ADJ
admet-942	104	5	communication	communication	NOUN
admet-942	104	6	is	be	AUX
admet-942	104	7	absent	absent	ADJ
admet-942	104	8	in	in	ADP
admet-942	104	9	most	most	ADV
admet-942	104	10	traditional	traditional	ADJ
admet-942	104	11	cell	cell	NOUN
admet-942	104	12	cultures	culture	NOUN
admet-942	104	13	,	,	PUNCT
admet-942	104	14	however	however	ADV
admet-942	104	15	,	,	PUNCT
admet-942	104	16	oocs	ooc	NOUN
admet-942	104	17	allow	allow	VERB
admet-942	104	18	the	the	DET
admet-942	104	19	coupling	coupling	NOUN
admet-942	104	20	of	of	ADP
admet-942	104	21	different	different	ADJ
admet-942	104	22	organs	organ	NOUN
admet-942	104	23	according	accord	VERB
admet-942	104	24	to	to	ADP
admet-942	104	25	their	their	PRON
admet-942	104	26	physiological	physiological	ADJ
admet-942	104	27	disposition	disposition	NOUN
admet-942	104	28	[	[	X
admet-942	104	29	42,44,51	42,44,51	NOUN
admet-942	104	30	]	]	X
admet-942	104	31	,	,	PUNCT
admet-942	104	32	either	either	CCONJ
admet-942	104	33	on	on	ADP
admet-942	104	34	a	a	DET
admet-942	104	35	chip	chip	NOUN
admet-942	104	36	with	with	ADP
admet-942	104	37	different	different	ADJ
admet-942	104	38	cavities	cavity	NOUN
admet-942	104	39	or	or	CCONJ
admet-942	104	40	by	by	ADP
admet-942	104	41	interconnecting	interconnect	VERB
admet-942	104	42	different	different	ADJ
admet-942	104	43	chips	chip	NOUN
admet-942	104	44	[	[	X
admet-942	104	45	7,42	7,42	X
admet-942	104	46	]	]	X
admet-942	104	47	,	,	PUNCT
admet-942	104	48	as	as	SCONJ
admet-942	104	49	shown	show	VERB
admet-942	104	50	in	in	ADP
admet-942	104	51	figure	figure	NOUN
admet-942	104	52	2	2	NUM
admet-942	104	53	.	.	PUNCT
admet-942	105	1	the	the	DET
admet-942	105	2	mimicking	mimicking	NOUN
admet-942	105	3	of	of	ADP
admet-942	105	4	this	this	DET
admet-942	105	5	organ	organ	NOUN
admet-942	105	6	-	-	PUNCT
admet-942	105	7	organ	organ	NOUN
admet-942	105	8	interaction	interaction	NOUN
admet-942	105	9	in	in	ADP
admet-942	105	10	ooc	ooc	PROPN
admet-942	105	11	leads	lead	VERB
admet-942	105	12	to	to	ADP
admet-942	105	13	better	well	ADJ
admet-942	105	14	evaluations	evaluation	NOUN
admet-942	105	15	of	of	ADP
admet-942	105	16	absorption	absorption	NOUN
admet-942	105	17	and	and	CCONJ
admet-942	105	18	metabolism	metabolism	NOUN
admet-942	105	19	[	[	X
admet-942	105	20	10,51	10,51	X
admet-942	105	21	]	]	X
admet-942	105	22	.	.	PUNCT
admet-942	106	1	therefore	therefore	ADV
admet-942	106	2	,	,	PUNCT
admet-942	106	3	these	these	DET
admet-942	106	4	systems	system	NOUN
admet-942	106	5	enable	enable	VERB
admet-942	106	6	to	to	PART
admet-942	106	7	observe	observe	VERB
admet-942	106	8	how	how	SCONJ
admet-942	106	9	the	the	DET
admet-942	106	10	organs	organ	NOUN
admet-942	106	11	are	be	AUX
admet-942	106	12	affected	affect	VERB
admet-942	106	13	by	by	ADP
admet-942	106	14	the	the	DET
admet-942	106	15	main	main	ADJ
admet-942	106	16	compound	compound	NOUN
admet-942	106	17	and	and	CCONJ
admet-942	106	18	by	by	ADP
admet-942	106	19	the	the	DET
admet-942	106	20	metabolites	metabolite	NOUN
admet-942	106	21	that	that	PRON
admet-942	106	22	might	might	AUX
admet-942	106	23	be	be	AUX
admet-942	106	24	generated	generate	VERB
admet-942	106	25	under	under	ADP
admet-942	106	26	physiological	physiological	ADJ
admet-942	106	27	conditions	condition	NOUN
admet-942	106	28	[	[	X
admet-942	106	29	11,67,68	11,67,68	NUM
admet-942	106	30	]	]	X
admet-942	106	31	.	.	PUNCT
admet-942	107	1	multicellular	multicellular	ADJ
admet-942	107	2	tissues	tissue	NOUN
admet-942	107	3	and	and	CCONJ
admet-942	107	4	structures	structure	NOUN
admet-942	107	5	in	in	ADP
admet-942	107	6	living	live	VERB
admet-942	107	7	organs	organ	NOUN
admet-942	107	8	experience	experience	VERB
admet-942	107	9	mechanical	mechanical	ADJ
admet-942	107	10	forces	force	NOUN
admet-942	107	11	such	such	ADJ
admet-942	107	12	as	as	ADP
admet-942	107	13	blood	blood	NOUN
admet-942	107	14	flow	flow	NOUN
admet-942	107	15	,	,	PUNCT
admet-942	107	16	compression	compression	NOUN
admet-942	107	17	,	,	PUNCT
admet-942	107	18	and	and	CCONJ
admet-942	107	19	tension	tension	NOUN
admet-942	107	20	,	,	PUNCT
admet-942	107	21	that	that	PRON
admet-942	107	22	are	be	AUX
admet-942	107	23	important	important	ADJ
admet-942	107	24	for	for	ADP
admet-942	107	25	physiological	physiological	ADJ
admet-942	107	26	processes	process	NOUN
admet-942	107	27	[	[	X
admet-942	107	28	42,44,70,71	42,44,70,71	PROPN
admet-942	107	29	]	]	PUNCT
admet-942	107	30	.	.	PUNCT
admet-942	108	1	blood	blood	NOUN
admet-942	108	2	flow	flow	NOUN
admet-942	108	3	is	be	AUX
admet-942	108	4	critical	critical	ADJ
admet-942	108	5	for	for	ADP
admet-942	108	6	cells	cell	NOUN
admet-942	108	7	maturation	maturation	NOUN
admet-942	108	8	and	and	CCONJ
admet-942	108	9	differentiation	differentiation	NOUN
admet-942	108	10	,	,	PUNCT
admet-942	108	11	as	as	ADV
admet-942	108	12	well	well	ADV
admet-942	108	13	as	as	ADP
admet-942	108	14	for	for	ADP
admet-942	108	15	their	their	PRON
admet-942	108	16	proper	proper	ADJ
admet-942	108	17	functioning	functioning	NOUN
admet-942	108	18	[	[	X
admet-942	108	19	55,70	55,70	NUM
admet-942	108	20	]	]	PUNCT
admet-942	108	21	.	.	PUNCT
admet-942	109	1	ooc	ooc	PROPN
admet-942	109	2	devices	device	NOUN
admet-942	109	3	enable	enable	VERB
admet-942	109	4	the	the	DET
admet-942	109	5	reproduction	reproduction	NOUN
admet-942	109	6	of	of	ADP
admet-942	109	7	some	some	DET
admet-942	109	8	forces	force	NOUN
admet-942	109	9	by	by	ADP
admet-942	109	10	modulating	modulate	VERB
admet-942	109	11	the	the	DET
admet-942	109	12	flow	flow	NOUN
admet-942	109	13	characteristics	characteristic	NOUN
admet-942	109	14	[	[	X
admet-942	109	15	42,70	42,70	NOUN
admet-942	109	16	]	]	X
admet-942	109	17	.	.	PUNCT
admet-942	110	1	this	this	PRON
admet-942	110	2	can	can	AUX
admet-942	110	3	be	be	AUX
admet-942	110	4	performed	perform	VERB
admet-942	110	5	by	by	ADP
admet-942	110	6	passive	passive	ADJ
admet-942	110	7	manners	manner	NOUN
admet-942	110	8	,	,	PUNCT
admet-942	110	9	when	when	SCONJ
admet-942	110	10	talking	talk	VERB
admet-942	110	11	of	of	ADP
admet-942	110	12	gravity	gravity	NOUN
admet-942	110	13	or	or	CCONJ
admet-942	110	14	concentration	concentration	NOUN
admet-942	110	15	gradient	gradient	NOUN
admet-942	110	16	,	,	PUNCT
admet-942	110	17	or	or	CCONJ
admet-942	110	18	actively	actively	ADV
admet-942	110	19	,	,	PUNCT
admet-942	110	20	through	through	ADP
admet-942	110	21	the	the	DET
admet-942	110	22	integration	integration	NOUN
admet-942	110	23	of	of	ADP
admet-942	110	24	micro	micro	NOUN
admet-942	110	25	-	-	NOUN
admet-942	110	26	pumps	pump	NOUN
admet-942	110	27	together	together	ADV
admet-942	110	28	with	with	ADP
admet-942	110	29	their	their	PRON
admet-942	110	30	respective	respective	ADJ
admet-942	110	31	control	control	NOUN
admet-942	110	32	and	and	CCONJ
admet-942	110	33	measurement	measurement	NOUN
admet-942	110	34	systems	system	NOUN
admet-942	110	35	[	[	X
admet-942	110	36	44,54,72,73	44,54,72,73	NOUN
admet-942	110	37	]	]	PUNCT
admet-942	110	38	.	.	PUNCT
admet-942	111	1	good	good	ADJ
admet-942	111	2	simulations	simulation	NOUN
admet-942	111	3	of	of	ADP
admet-942	111	4	cell	cell	NOUN
admet-942	111	5	migration	migration	NOUN
admet-942	111	6	from	from	ADP
admet-942	111	7	one	one	NUM
admet-942	111	8	tissue	tissue	NOUN
admet-942	111	9	to	to	ADP
admet-942	111	10	another	another	PRON
admet-942	111	11	,	,	PUNCT
admet-942	111	12	as	as	SCONJ
admet-942	111	13	can	can	AUX
admet-942	111	14	be	be	AUX
admet-942	111	15	immune	immune	ADJ
admet-942	111	16	cells	cell	NOUN
admet-942	111	17	,	,	PUNCT
admet-942	111	18	or	or	CCONJ
admet-942	111	19	cancer	cancer	NOUN
admet-942	111	20	cells	cell	NOUN
admet-942	111	21	in	in	ADP
admet-942	111	22	methasteses	methastese	NOUN
admet-942	111	23	,	,	PUNCT
admet-942	111	24	are	be	AUX
admet-942	111	25	important	important	ADJ
admet-942	111	26	challenges	challenge	NOUN
admet-942	111	27	[	[	X
admet-942	111	28	7	7	NUM
admet-942	111	29	]	]	PUNCT
admet-942	111	30	.	.	PUNCT
admet-942	112	1	sophisticated	sophisticated	ADJ
admet-942	112	2	microenvironments	microenvironment	NOUN
admet-942	112	3	can	can	AUX
admet-942	112	4	also	also	ADV
admet-942	112	5	be	be	AUX
admet-942	112	6	mimicked	mimic	VERB
admet-942	112	7	by	by	ADP
admet-942	112	8	using	use	VERB
admet-942	112	9	multilayer	multilayer	ADJ
admet-942	112	10	technologies	technology	NOUN
admet-942	112	11	,	,	PUNCT
admet-942	112	12	parallel	parallel	ADJ
admet-942	112	13	microchannels	microchannel	NOUN
admet-942	112	14	,	,	PUNCT
admet-942	112	15	cellular	cellular	ADJ
admet-942	112	16	spheroids	spheroid	NOUN
admet-942	112	17	,	,	PUNCT
admet-942	112	18	turning	turn	VERB
admet-942	112	19	devices	device	NOUN
admet-942	112	20	,	,	PUNCT
admet-942	112	21	or	or	CCONJ
admet-942	112	22	varying	vary	VERB
admet-942	112	23	the	the	DET
admet-942	112	24	cellular	cellular	ADJ
admet-942	112	25	arrangement	arrangement	NOUN
admet-942	112	26	pattern	pattern	NOUN
admet-942	112	27	,	,	PUNCT
admet-942	112	28	among	among	ADP
admet-942	112	29	others	other	NOUN
admet-942	112	30	[	[	X
admet-942	112	31	30	30	NUM
admet-942	112	32	]	]	PUNCT
admet-942	112	33	.	.	PUNCT
admet-942	113	1	the	the	DET
admet-942	113	2	integration	integration	NOUN
admet-942	113	3	of	of	ADP
admet-942	113	4	the	the	DET
admet-942	113	5	support	support	NOUN
admet-942	113	6	and	and	CCONJ
admet-942	113	7	channel	channel	NOUN
admet-942	113	8	architectures	architecture	NOUN
admet-942	113	9	,	,	PUNCT
admet-942	113	10	the	the	DET
admet-942	113	11	3d	3d	NOUN
admet-942	113	12	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	113	13	r.	r.	PROPN
admet-942	113	14	vargas	vargas	PROPN
admet-942	113	15	,	,	PUNCT
admet-942	113	16	a.	a.	NOUN
admet-942	113	17	egurbide	egurbide	NOUN
admet-942	113	18	-	-	PUNCT
admet-942	113	19	sifre	sifre	NOUN
admet-942	113	20	and	and	CCONJ
admet-942	113	21	l.	l.	PROPN
admet-942	113	22	medina	medina	PROPN
admet-942	113	23	admet	admet	PROPN
admet-942	113	24	&	&	CCONJ
admet-942	113	25	dmpk	dmpk	PROPN
admet-942	113	26	9(2	9(2	NUM
admet-942	113	27	)	)	PUNCT
admet-942	113	28	(	(	PUNCT
admet-942	113	29	2021	2021	NUM
admet-942	113	30	)	)	PUNCT
admet-942	113	31	111	111	NUM
admet-942	113	32	-	-	SYM
admet-942	113	33	141	141	NUM
admet-942	113	34	116	116	NUM
admet-942	113	35	cell	cell	NOUN
admet-942	113	36	arrangement	arrangement	NOUN
admet-942	113	37	and	and	CCONJ
admet-942	113	38	the	the	DET
admet-942	113	39	flow	flow	NOUN
admet-942	113	40	systems	system	NOUN
admet-942	113	41	enable	enable	VERB
admet-942	113	42	the	the	DET
admet-942	113	43	appropriate	appropriate	ADJ
admet-942	113	44	nutrients	nutrient	NOUN
admet-942	113	45	supply	supply	NOUN
admet-942	113	46	,	,	PUNCT
admet-942	113	47	the	the	DET
admet-942	113	48	waste	waste	NOUN
admet-942	113	49	elimination	elimination	NOUN
admet-942	113	50	and	and	CCONJ
admet-942	113	51	the	the	DET
admet-942	113	52	exchange	exchange	NOUN
admet-942	113	53	of	of	ADP
admet-942	113	54	molecular	molecular	ADJ
admet-942	113	55	and	and	CCONJ
admet-942	113	56	analytical	analytical	ADJ
admet-942	113	57	signals	signal	NOUN
admet-942	113	58	[	[	X
admet-942	113	59	13,49,50,52,58,74	13,49,50,52,58,74	NUM
admet-942	113	60	]	]	PUNCT
admet-942	113	61	.	.	PUNCT
admet-942	114	1	figure	figure	NOUN
admet-942	114	2	2	2	NUM
admet-942	114	3	.	.	PUNCT
admet-942	114	4	organ	organ	NOUN
admet-942	114	5	interaction	interaction	NOUN
admet-942	114	6	in	in	ADP
admet-942	114	7	ooc	ooc	PRON
admet-942	114	8	.	.	PUNCT
admet-942	115	1	a	a	DET
admet-942	115	2	)	)	PUNCT
admet-942	115	3	schematic	schematic	ADJ
admet-942	115	4	representation	representation	NOUN
admet-942	115	5	of	of	ADP
admet-942	115	6	miniaturized	miniaturize	VERB
admet-942	115	7	digestive	digestive	ADJ
admet-942	115	8	system	system	NOUN
admet-942	115	9	.	.	PUNCT
admet-942	116	1	b	b	X
admet-942	116	2	)	)	PUNCT
admet-942	116	3	heart	heart	NOUN
admet-942	116	4	–	–	PUNCT
admet-942	116	5	liver	liver	NOUN
admet-942	116	6	body	body	NOUN
admet-942	116	7	-	-	PUNCT
admet-942	116	8	on	on	ADP
admet-942	116	9	-	-	PUNCT
admet-942	116	10	a	a	DET
admet-942	116	11	-	-	PUNCT
admet-942	116	12	chip	chip	NOUN
admet-942	116	13	with	with	ADP
admet-942	116	14	a	a	DET
admet-942	116	15	liver	liver	NOUN
admet-942	116	16	module	module	NOUN
admet-942	116	17	,	,	PUNCT
admet-942	116	18	cardiomyocytes	cardiomyocyte	NOUN
admet-942	116	19	and	and	CCONJ
admet-942	116	20	a	a	DET
admet-942	116	21	skin	skin	NOUN
admet-942	116	22	module	module	NOUN
admet-942	116	23	on	on	ADP
admet-942	116	24	a	a	DET
admet-942	116	25	single	single	ADJ
admet-942	116	26	chip	chip	NOUN
admet-942	116	27	.	.	PUNCT
admet-942	117	1	c	c	X
admet-942	117	2	)	)	PUNCT
admet-942	117	3	body	body	NOUN
admet-942	117	4	-	-	PUNCT
admet-942	117	5	on	on	ADP
admet-942	117	6	-	-	PUNCT
admet-942	117	7	achip	achip	NOUN
admet-942	117	8	simulation	simulation	NOUN
admet-942	117	9	with	with	ADP
admet-942	117	10	gastrointestinal	gastrointestinal	ADJ
admet-942	117	11	tract	tract	NOUN
admet-942	117	12	and	and	CCONJ
admet-942	117	13	liver	liver	NOUN
admet-942	117	14	tissue	tissue	NOUN
admet-942	117	15	with	with	ADP
admet-942	117	16	two	two	NUM
admet-942	117	17	coupled	couple	VERB
admet-942	117	18	chips	chip	NOUN
admet-942	117	19	.	.	PUNCT
admet-942	117	20	adapted	adapt	VERB
admet-942	117	21	respectively	respectively	ADV
admet-942	117	22	from	from	ADP
admet-942	117	23	[	[	X
admet-942	117	24	69	69	NUM
admet-942	117	25	]	]	PUNCT
admet-942	117	26	,	,	PUNCT
admet-942	117	27	[	[	X
admet-942	117	28	67	67	NUM
admet-942	117	29	]	]	PUNCT
admet-942	117	30	,	,	PUNCT
admet-942	117	31	and	and	CCONJ
admet-942	117	32	[	[	X
admet-942	117	33	68	68	NUM
admet-942	117	34	]	]	PUNCT
admet-942	117	35	with	with	ADP
admet-942	117	36	permission	permission	NOUN
admet-942	117	37	from	from	ADP
admet-942	117	38	the	the	DET
admet-942	117	39	royal	royal	ADJ
admet-942	117	40	society	society	NOUN
admet-942	117	41	of	of	ADP
admet-942	117	42	chemistry	chemistry	NOUN
admet-942	117	43	.	.	PUNCT
admet-942	118	1	copyright	copyright	NOUN
admet-942	118	2	(	(	PUNCT
admet-942	118	3	2019	2019	NUM
admet-942	118	4	,	,	PUNCT
admet-942	118	5	2020	2020	NUM
admet-942	118	6	&	&	CCONJ
admet-942	118	7	2014	2014	NUM
admet-942	118	8	)	)	PUNCT
admet-942	118	9	measurement	measurement	NOUN
admet-942	118	10	systems	system	NOUN
admet-942	118	11	integration	integration	NOUN
admet-942	118	12	although	although	SCONJ
admet-942	118	13	several	several	ADJ
admet-942	118	14	analytical	analytical	ADJ
admet-942	118	15	methods	method	NOUN
admet-942	118	16	can	can	AUX
admet-942	118	17	be	be	AUX
admet-942	118	18	coupled	couple	VERB
admet-942	118	19	to	to	ADP
admet-942	118	20	ooc	ooc	PROPN
admet-942	118	21	(	(	PUNCT
admet-942	118	22	see	see	VERB
admet-942	118	23	table	table	NOUN
admet-942	118	24	2	2	NUM
admet-942	118	25	for	for	ADP
admet-942	118	26	some	some	DET
admet-942	118	27	examples	example	NOUN
admet-942	118	28	)	)	PUNCT
admet-942	118	29	,	,	PUNCT
admet-942	118	30	these	these	DET
admet-942	118	31	systems	system	NOUN
admet-942	118	32	still	still	ADV
admet-942	118	33	show	show	VERB
admet-942	118	34	lower	low	ADJ
admet-942	118	35	capacity	capacity	NOUN
admet-942	118	36	to	to	PART
admet-942	118	37	adapt	adapt	VERB
admet-942	118	38	to	to	ADP
admet-942	118	39	hts	hts	PROPN
admet-942	118	40	than	than	ADP
admet-942	118	41	2d	2d	NUM
admet-942	118	42	tissues	tissue	NOUN
admet-942	118	43	.	.	PUNCT
admet-942	119	1	ooc	ooc	PRON
admet-942	119	2	will	will	NOUN
admet-942	119	3	,	,	PUNCT
admet-942	119	4	however	however	ADV
admet-942	119	5	,	,	PUNCT
admet-942	119	6	present	present	VERB
admet-942	119	7	a	a	DET
admet-942	119	8	higher	high	ADJ
admet-942	119	9	adaptability	adaptability	NOUN
admet-942	119	10	as	as	ADV
admet-942	119	11	soon	soon	ADV
admet-942	119	12	as	as	ADP
admet-942	119	13	faster	fast	ADV
admet-942	119	14	and	and	CCONJ
admet-942	119	15	more	more	ADV
admet-942	119	16	reliable	reliable	ADJ
admet-942	119	17	analytical	analytical	ADJ
admet-942	119	18	systems	system	NOUN
admet-942	119	19	are	be	AUX
admet-942	119	20	developed	develop	VERB
admet-942	119	21	for	for	ADP
admet-942	119	22	on	on	ADP
admet-942	119	23	-	-	PUNCT
admet-942	119	24	line	line	NOUN
admet-942	119	25	analysis	analysis	NOUN
admet-942	120	1	[	[	X
admet-942	120	2	4,13,62,71,75	4,13,62,71,75	NOUN
admet-942	120	3	]	]	X
admet-942	120	4	.	.	PUNCT
admet-942	121	1	table	table	NOUN
admet-942	121	2	2	2	NUM
admet-942	121	3	.	.	X
admet-942	121	4	main	main	ADJ
admet-942	121	5	analytical	analytical	ADJ
admet-942	121	6	techniques	technique	NOUN
admet-942	121	7	reported	report	VERB
admet-942	121	8	for	for	ADP
admet-942	121	9	on	on	ADP
admet-942	121	10	-	-	PUNCT
admet-942	121	11	line	line	NOUN
admet-942	121	12	analysis	analysis	NOUN
admet-942	121	13	of	of	ADP
admet-942	121	14	ooc	ooc	PRON
admet-942	121	15	.	.	PUNCT
admet-942	122	1	analytical	analytical	ADJ
admet-942	122	2	technique	technique	NOUN
admet-942	122	3	references	reference	NOUN
admet-942	122	4	fluorescence	fluorescence	NOUN
admet-942	122	5	[	[	X
admet-942	122	6	24,53,76,77][78	24,53,76,77][78	X
admet-942	122	7	]	]	X
admet-942	122	8	electrochemical	electrochemical	ADJ
admet-942	122	9	detection	detection	NOUN
admet-942	122	10	[	[	X
admet-942	122	11	24,79,80	24,79,80	NUM
admet-942	122	12	]	]	X
admet-942	122	13	microscopy	microscopy	NOUN
admet-942	122	14	[	[	X
admet-942	122	15	48,80,81	48,80,81	NOUN
admet-942	122	16	]	]	X
admet-942	122	17	chromatography	chromatography	NOUN
admet-942	122	18	[	[	X
admet-942	122	19	3,80	3,80	NUM
admet-942	122	20	]	]	SYM
admet-942	122	21	electrophoresis	electrophoresis	NOUN
admet-942	122	22	and	and	CCONJ
admet-942	122	23	magnetophoresis	magnetophoresis	NOUN
admet-942	122	24	[	[	X
admet-942	122	25	3,75	3,75	NOUN
admet-942	122	26	]	]	X
admet-942	122	27	high	high	ADJ
admet-942	122	28	definition	definition	NOUN
admet-942	122	29	cameras	camera	NOUN
admet-942	122	30	[	[	X
admet-942	122	31	24	24	NUM
admet-942	122	32	]	]	PUNCT
admet-942	122	33	color	color	NOUN
admet-942	122	34	change	change	NOUN
admet-942	122	35	(	(	PUNCT
admet-942	122	36	ph	ph	PROPN
admet-942	122	37	)	)	PUNCT
admet-942	123	1	[	[	X
admet-942	123	2	28	28	NUM
admet-942	123	3	]	]	X
admet-942	123	4	light	light	NOUN
admet-942	123	5	scattering	scatter	VERB
admet-942	123	6	[	[	X
admet-942	123	7	76	76	NUM
admet-942	123	8	]	]	PUNCT
admet-942	123	9	ionization	ionization	NOUN
admet-942	123	10	spectroscopy	spectroscopy	NOUN
admet-942	123	11	[	[	X
admet-942	123	12	80	80	NUM
admet-942	123	13	]	]	SYM
admet-942	123	14	filtration	filtration	NOUN
admet-942	124	1	[	[	X
admet-942	124	2	75	75	NUM
admet-942	124	3	]	]	X
admet-942	124	4	immuno	immuno	ADJ
admet-942	124	5	-	-	PUNCT
admet-942	124	6	agglutination	agglutination	NOUN
admet-942	124	7	[	[	X
admet-942	124	8	76	76	NUM
admet-942	124	9	]	]	X
admet-942	124	10	potentiometry	potentiometry	NOUN
admet-942	124	11	[	[	X
admet-942	124	12	24	24	NUM
admet-942	124	13	]	]	PUNCT
admet-942	124	14	trans	trans	ADJ
admet-942	124	15	-	-	ADJ
admet-942	124	16	epithelial	epithelial	ADJ
admet-942	124	17	resistance	resistance	NOUN
admet-942	124	18	[	[	X
admet-942	124	19	24	24	NUM
admet-942	124	20	]	]	X
admet-942	124	21	acoustic	acoustic	ADJ
admet-942	124	22	techniques	technique	NOUN
admet-942	124	23	[	[	X
admet-942	124	24	75	75	NUM
admet-942	124	25	]	]	PUNCT
admet-942	124	26	photoacoustic	photoacoustic	ADJ
admet-942	124	27	tomography	tomography	NOUN
admet-942	125	1	[	[	X
admet-942	125	2	44	44	NUM
admet-942	125	3	]	]	SYM
admet-942	125	4	force	force	NOUN
admet-942	125	5	transducers	transducer	NOUN
admet-942	125	6	[	[	X
admet-942	125	7	24	24	NUM
admet-942	125	8	]	]	PUNCT
admet-942	125	9	flow	flow	NOUN
admet-942	125	10	cytometry	cytometry	NOUN
admet-942	126	1	[	[	X
admet-942	126	2	82	82	NUM
admet-942	126	3	]	]	X
admet-942	126	4	admet	admet	PROPN
admet-942	126	5	&	&	CCONJ
admet-942	126	6	dmpk	dmpk	PROPN
admet-942	126	7	9(2	9(2	NUM
admet-942	126	8	)	)	PUNCT
admet-942	126	9	(	(	PUNCT
admet-942	126	10	2021	2021	NUM
admet-942	126	11	)	)	PUNCT
admet-942	126	12	111	111	NUM
admet-942	126	13	-	-	SYM
admet-942	126	14	141	141	NUM
admet-942	126	15	organ	organ	NOUN
admet-942	126	16	-	-	PUNCT
admet-942	126	17	on	on	ADP
admet-942	126	18	-	-	PUNCT
admet-942	126	19	a	a	DET
admet-942	126	20	-	-	PUNCT
admet-942	126	21	chip	chip	NOUN
admet-942	126	22	systems	system	NOUN
admet-942	126	23	for	for	ADP
admet-942	126	24	new	new	ADJ
admet-942	126	25	drugs	drug	NOUN
admet-942	126	26	development	development	NOUN
admet-942	126	27	doi	doi	PROPN
admet-942	126	28	:	:	PUNCT
admet-942	126	29	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	126	30	117	117	NUM
admet-942	126	31	the	the	DET
admet-942	126	32	integration	integration	NOUN
admet-942	126	33	of	of	ADP
admet-942	126	34	sensors	sensor	NOUN
admet-942	126	35	in	in	ADP
admet-942	126	36	ooc	ooc	NOUN
admet-942	126	37	systems	system	NOUN
admet-942	126	38	provides	provide	VERB
admet-942	126	39	an	an	DET
admet-942	126	40	additional	additional	ADJ
admet-942	126	41	advantage	advantage	NOUN
admet-942	126	42	over	over	ADP
admet-942	126	43	animal	animal	NOUN
admet-942	126	44	and	and	CCONJ
admet-942	126	45	human	human	ADJ
admet-942	126	46	models	model	NOUN
admet-942	126	47	as	as	SCONJ
admet-942	126	48	electrophysiological	electrophysiological	ADJ
admet-942	126	49	signals	signal	NOUN
admet-942	126	50	can	can	AUX
admet-942	126	51	be	be	AUX
admet-942	126	52	collected	collect	VERB
admet-942	126	53	and	and	CCONJ
admet-942	126	54	analyzed	analyze	VERB
admet-942	126	55	on	on	ADP
admet-942	126	56	real	real	ADJ
admet-942	126	57	-	-	PUNCT
admet-942	126	58	time[28,58	time[28,58	NOUN
admet-942	126	59	]	]	PUNCT
admet-942	126	60	.	.	PUNCT
admet-942	127	1	this	this	PRON
admet-942	127	2	allows	allow	VERB
admet-942	127	3	the	the	DET
admet-942	127	4	quantification	quantification	NOUN
admet-942	127	5	of	of	ADP
admet-942	127	6	cellular	cellular	ADJ
admet-942	127	7	metabolites	metabolite	NOUN
admet-942	127	8	and	and	CCONJ
admet-942	127	9	study	study	VERB
admet-942	127	10	their	their	PRON
admet-942	127	11	evolution	evolution	NOUN
admet-942	127	12	in	in	ADP
admet-942	127	13	front	front	NOUN
admet-942	127	14	of	of	ADP
admet-942	127	15	external	external	ADJ
admet-942	127	16	stimuli	stimulus	NOUN
admet-942	127	17	[	[	X
admet-942	127	18	53	53	NUM
admet-942	127	19	]	]	PUNCT
admet-942	127	20	.	.	PUNCT
admet-942	128	1	furthermore	furthermore	ADV
admet-942	128	2	,	,	PUNCT
admet-942	128	3	the	the	DET
admet-942	128	4	functionality	functionality	NOUN
admet-942	128	5	of	of	ADP
admet-942	128	6	tissues	tissue	NOUN
admet-942	128	7	,	,	PUNCT
admet-942	128	8	cells	cell	NOUN
admet-942	128	9	or	or	CCONJ
admet-942	128	10	even	even	ADV
admet-942	128	11	intracellular	intracellular	ADJ
admet-942	128	12	organelles	organelle	NOUN
admet-942	128	13	can	can	AUX
admet-942	128	14	be	be	AUX
admet-942	128	15	tracked	track	VERB
admet-942	128	16	[	[	X
admet-942	128	17	80	80	NUM
admet-942	128	18	]	]	PUNCT
admet-942	128	19	.	.	PUNCT
admet-942	129	1	the	the	DET
admet-942	129	2	main	main	ADJ
admet-942	129	3	challenge	challenge	NOUN
admet-942	129	4	of	of	ADP
admet-942	129	5	these	these	DET
admet-942	129	6	measuring	measure	VERB
admet-942	129	7	systems	system	NOUN
admet-942	129	8	is	be	AUX
admet-942	129	9	to	to	PART
admet-942	129	10	properly	properly	ADV
admet-942	129	11	assess	assess	VERB
admet-942	129	12	drug	drug	NOUN
admet-942	129	13	concentration	concentration	NOUN
admet-942	129	14	changes	change	NOUN
admet-942	129	15	and	and	CCONJ
admet-942	129	16	physiological	physiological	ADJ
admet-942	129	17	responses	response	NOUN
admet-942	129	18	by	by	ADP
admet-942	129	19	employing	employ	VERB
admet-942	129	20	low	low	ADJ
admet-942	129	21	sample	sample	NOUN
admet-942	129	22	quantities	quantity	NOUN
admet-942	129	23	at	at	ADP
admet-942	129	24	low	low	ADJ
admet-942	129	25	flows	flow	NOUN
admet-942	129	26	and	and	CCONJ
admet-942	129	27	with	with	ADP
admet-942	129	28	high	high	ADJ
admet-942	129	29	dynamism	dynamism	NOUN
admet-942	129	30	,	,	PUNCT
admet-942	129	31	in	in	ADP
admet-942	129	32	a	a	DET
admet-942	129	33	heterogeneous	heterogeneous	ADJ
admet-942	129	34	and	and	CCONJ
admet-942	129	35	complex	complex	ADJ
admet-942	129	36	-	-	PUNCT
admet-942	129	37	composition	composition	NOUN
admet-942	129	38	environment	environment	NOUN
admet-942	129	39	with	with	ADP
admet-942	129	40	the	the	DET
admet-942	129	41	presence	presence	NOUN
admet-942	129	42	of	of	ADP
admet-942	129	43	salts	salt	NOUN
admet-942	129	44	,	,	PUNCT
admet-942	129	45	sugars	sugar	NOUN
admet-942	129	46	and	and	CCONJ
admet-942	129	47	proteins	protein	NOUN
admet-942	129	48	,	,	PUNCT
admet-942	129	49	among	among	ADP
admet-942	129	50	others	other	NOUN
admet-942	129	51	[	[	X
admet-942	129	52	3,28,53,80	3,28,53,80	ADP
admet-942	129	53	]	]	PUNCT
admet-942	129	54	.	.	PUNCT
admet-942	130	1	aside	aside	ADV
admet-942	130	2	from	from	ADP
admet-942	130	3	the	the	DET
admet-942	130	4	selection	selection	NOUN
admet-942	130	5	of	of	ADP
admet-942	130	6	an	an	DET
admet-942	130	7	appropriate	appropriate	ADJ
admet-942	130	8	analytical	analytical	ADJ
admet-942	130	9	technique	technique	NOUN
admet-942	130	10	,	,	PUNCT
admet-942	130	11	an	an	DET
admet-942	130	12	integrated	integrate	VERB
admet-942	130	13	ooc	ooc	NOUN
admet-942	130	14	system	system	NOUN
admet-942	130	15	requires	require	VERB
admet-942	130	16	the	the	DET
admet-942	130	17	development	development	NOUN
admet-942	130	18	of	of	ADP
admet-942	130	19	specific	specific	ADJ
admet-942	130	20	computer	computer	NOUN
admet-942	130	21	systems	system	NOUN
admet-942	130	22	dedicated	dedicate	VERB
admet-942	130	23	to	to	PART
admet-942	130	24	analyze	analyze	VERB
admet-942	130	25	and	and	CCONJ
admet-942	130	26	integrate	integrate	VERB
admet-942	130	27	the	the	DET
admet-942	130	28	measured	measured	ADJ
admet-942	130	29	signals	signal	NOUN
admet-942	130	30	[	[	X
admet-942	130	31	76,83	76,83	NUM
admet-942	130	32	]	]	PUNCT
admet-942	130	33	.	.	PUNCT
admet-942	131	1	ooc	ooc	NOUN
admet-942	131	2	systems	system	NOUN
admet-942	131	3	production	production	NOUN
admet-942	131	4	3d	3d	NUM
admet-942	131	5	printing	print	VERB
admet-942	131	6	one	one	NUM
admet-942	131	7	of	of	ADP
admet-942	131	8	the	the	DET
admet-942	131	9	major	major	ADJ
admet-942	131	10	technological	technological	ADJ
admet-942	131	11	contributions	contribution	NOUN
admet-942	131	12	for	for	ADP
admet-942	131	13	the	the	DET
admet-942	131	14	development	development	NOUN
admet-942	131	15	of	of	ADP
admet-942	131	16	oocs	ooc	NOUN
admet-942	131	17	is	be	AUX
admet-942	131	18	the	the	DET
admet-942	131	19	3d	3d	NUM
admet-942	131	20	printing	printing	NOUN
admet-942	131	21	.	.	PUNCT
admet-942	132	1	this	this	DET
admet-942	132	2	technique	technique	NOUN
admet-942	132	3	allows	allow	VERB
admet-942	132	4	the	the	DET
admet-942	132	5	construction	construction	NOUN
admet-942	132	6	of	of	ADP
admet-942	132	7	the	the	DET
admet-942	132	8	desired	desire	VERB
admet-942	132	9	architecture	architecture	NOUN
admet-942	132	10	,	,	PUNCT
admet-942	132	11	communication	communication	NOUN
admet-942	132	12	channels	channel	NOUN
admet-942	132	13	and	and	CCONJ
admet-942	132	14	functional	functional	ADJ
admet-942	132	15	structures	structure	NOUN
admet-942	132	16	with	with	ADP
admet-942	132	17	cells	cell	NOUN
admet-942	132	18	and	and	CCONJ
admet-942	132	19	polymeric	polymeric	ADJ
admet-942	132	20	materials	material	NOUN
admet-942	132	21	[	[	X
admet-942	132	22	28,44,57	28,44,57	NUM
admet-942	132	23	]	]	PUNCT
admet-942	132	24	,	,	PUNCT
admet-942	132	25	which	which	PRON
admet-942	132	26	makes	make	VERB
admet-942	132	27	it	it	PRON
admet-942	132	28	possible	possible	ADJ
admet-942	132	29	to	to	PART
admet-942	132	30	control	control	VERB
admet-942	132	31	specific	specific	ADJ
admet-942	132	32	conditions	condition	NOUN
admet-942	132	33	by	by	ADP
admet-942	132	34	modelling	model	VERB
admet-942	132	35	mechanical	mechanical	ADJ
admet-942	132	36	features	feature	NOUN
admet-942	132	37	[	[	X
admet-942	132	38	7,28,60	7,28,60	NUM
admet-942	132	39	]	]	PUNCT
admet-942	132	40	.	.	PUNCT
admet-942	133	1	the	the	DET
admet-942	133	2	support	support	NOUN
admet-942	133	3	structure	structure	NOUN
admet-942	133	4	is	be	AUX
admet-942	133	5	made	make	VERB
admet-942	133	6	of	of	ADP
admet-942	133	7	polymeric	polymeric	ADJ
admet-942	133	8	materials	material	NOUN
admet-942	133	9	that	that	PRON
admet-942	133	10	must	must	AUX
admet-942	133	11	accomplish	accomplish	VERB
admet-942	133	12	three	three	NUM
admet-942	133	13	main	main	ADJ
admet-942	133	14	characteristics	characteristic	NOUN
admet-942	133	15	:	:	PUNCT
admet-942	133	16	biocompatibility	biocompatibility	NOUN
admet-942	133	17	,	,	PUNCT
admet-942	133	18	easy	easy	ADJ
admet-942	133	19	to	to	ADP
admet-942	133	20	shaping	shaping	NOUN
admet-942	133	21	and	and	CCONJ
admet-942	133	22	transparency	transparency	NOUN
admet-942	133	23	.	.	PUNCT
admet-942	134	1	the	the	DET
admet-942	134	2	most	most	ADV
admet-942	134	3	commonly	commonly	ADV
admet-942	134	4	used	use	VERB
admet-942	134	5	polymer	polymer	NOUN
admet-942	134	6	for	for	ADP
admet-942	134	7	this	this	DET
admet-942	134	8	purpose	purpose	NOUN
admet-942	134	9	is	be	AUX
admet-942	134	10	polydimethylsiloxane	polydimethylsiloxane	NOUN
admet-942	134	11	(	(	PUNCT
admet-942	134	12	pdms	pdms	NOUN
admet-942	134	13	)	)	PUNCT
admet-942	135	1	[	[	X
admet-942	135	2	1,84	1,84	NUM
admet-942	135	3	]	]	PUNCT
admet-942	135	4	.	.	PUNCT
admet-942	136	1	four	four	NUM
admet-942	136	2	different	different	ADJ
admet-942	136	3	techniques	technique	NOUN
admet-942	136	4	can	can	AUX
admet-942	136	5	be	be	AUX
admet-942	136	6	used	use	VERB
admet-942	136	7	to	to	PART
admet-942	136	8	form	form	VERB
admet-942	136	9	ooc	ooc	NOUN
admet-942	136	10	by	by	ADP
admet-942	136	11	3d	3d	PROPN
admet-942	136	12	printing	printing	NOUN
admet-942	136	13	:	:	PUNCT
admet-942	136	14	micro	micro	NOUN
admet-942	136	15	-	-	NOUN
admet-942	136	16	extrusion	extrusion	ADJ
admet-942	136	17	,	,	PUNCT
admet-942	136	18	stereolithography	stereolithography	NOUN
admet-942	136	19	,	,	PUNCT
admet-942	136	20	inkjet	inkjet	NOUN
admet-942	136	21	bioprinting	bioprinting	NOUN
admet-942	136	22	and	and	CCONJ
admet-942	136	23	laser	laser	NOUN
admet-942	136	24	bioprinting	bioprinting	NOUN
admet-942	136	25	[	[	X
admet-942	136	26	1,28	1,28	NUM
admet-942	136	27	]	]	PUNCT
admet-942	136	28	.	.	PUNCT
admet-942	137	1	in	in	ADP
admet-942	137	2	micro	micro	NOUN
admet-942	137	3	-	-	NOUN
admet-942	137	4	extrusion	extrusion	ADJ
admet-942	137	5	,	,	PUNCT
admet-942	137	6	a	a	DET
admet-942	137	7	continuous	continuous	ADJ
admet-942	137	8	flow	flow	NOUN
admet-942	137	9	of	of	ADP
admet-942	137	10	small	small	ADJ
admet-942	137	11	drops	drop	NOUN
admet-942	137	12	of	of	ADP
admet-942	137	13	bio	bio	NOUN
admet-942	137	14	-	-	ADJ
admet-942	137	15	ink	ink	NOUN
admet-942	137	16	(	(	PUNCT
admet-942	137	17	polymer	polymer	NOUN
admet-942	137	18	and	and	CCONJ
admet-942	137	19	cell	cell	NOUN
admet-942	137	20	suspension	suspension	NOUN
admet-942	137	21	)	)	PUNCT
admet-942	137	22	is	be	AUX
admet-942	137	23	generated	generate	VERB
admet-942	137	24	and	and	CCONJ
admet-942	137	25	pressed	press	VERB
admet-942	137	26	out	out	ADP
admet-942	137	27	from	from	ADP
admet-942	137	28	a	a	DET
admet-942	137	29	small	small	ADJ
admet-942	137	30	opening	opening	NOUN
admet-942	137	31	whose	whose	DET
admet-942	137	32	movement	movement	NOUN
admet-942	137	33	is	be	AUX
admet-942	137	34	precisely	precisely	ADV
admet-942	137	35	controlled	control	VERB
admet-942	137	36	by	by	ADP
admet-942	137	37	a	a	DET
admet-942	137	38	computerized	computerized	ADJ
admet-942	137	39	system	system	NOUN
admet-942	137	40	.	.	PUNCT
admet-942	138	1	although	although	SCONJ
admet-942	138	2	this	this	DET
admet-942	138	3	technique	technique	NOUN
admet-942	138	4	allows	allow	VERB
admet-942	138	5	the	the	DET
admet-942	138	6	use	use	NOUN
admet-942	138	7	of	of	ADP
admet-942	138	8	bio	bio	NOUN
admet-942	138	9	-	-	NOUN
admet-942	138	10	inks	ink	NOUN
admet-942	138	11	with	with	ADP
admet-942	138	12	complex	complex	ADJ
admet-942	138	13	compositions	composition	NOUN
admet-942	138	14	and	and	CCONJ
admet-942	138	15	high	high	ADJ
admet-942	138	16	viscosity	viscosity	NOUN
admet-942	138	17	,	,	PUNCT
admet-942	138	18	cell	cell	NOUN
admet-942	138	19	viability	viability	NOUN
admet-942	138	20	could	could	AUX
admet-942	138	21	be	be	AUX
admet-942	138	22	reduced	reduce	VERB
admet-942	138	23	[	[	X
admet-942	138	24	1,28,57	1,28,57	NUM
admet-942	138	25	]	]	PUNCT
admet-942	138	26	.	.	PUNCT
admet-942	139	1	micro	micro	NOUN
admet-942	139	2	-	-	NOUN
admet-942	139	3	extrusion	extrusion	NOUN
admet-942	139	4	is	be	AUX
admet-942	139	5	one	one	NUM
admet-942	139	6	of	of	ADP
admet-942	139	7	the	the	DET
admet-942	139	8	most	most	ADV
admet-942	139	9	used	use	VERB
admet-942	139	10	techniques	technique	NOUN
admet-942	139	11	for	for	ADP
admet-942	139	12	the	the	DET
admet-942	139	13	formation	formation	NOUN
admet-942	139	14	of	of	ADP
admet-942	139	15	ooc	ooc	PRON
admet-942	139	16	due	due	ADJ
admet-942	139	17	to	to	ADP
admet-942	139	18	its	its	PRON
admet-942	139	19	low	low	ADJ
admet-942	139	20	cost	cost	NOUN
admet-942	139	21	,	,	PUNCT
admet-942	139	22	however	however	ADV
admet-942	139	23	,	,	PUNCT
admet-942	139	24	it	it	PRON
admet-942	139	25	shows	show	VERB
admet-942	139	26	limitations	limitation	NOUN
admet-942	139	27	in	in	ADP
admet-942	139	28	terms	term	NOUN
admet-942	139	29	of	of	ADP
admet-942	139	30	texture	texture	ADJ
admet-942	139	31	creation	creation	NOUN
admet-942	139	32	and	and	CCONJ
admet-942	139	33	,	,	PUNCT
admet-942	139	34	thus	thus	ADV
admet-942	139	35	,	,	PUNCT
admet-942	139	36	it	it	PRON
admet-942	139	37	is	be	AUX
admet-942	139	38	not	not	PART
admet-942	139	39	suitable	suitable	ADJ
admet-942	139	40	for	for	ADP
admet-942	139	41	the	the	DET
admet-942	139	42	elaboration	elaboration	NOUN
admet-942	139	43	of	of	ADP
admet-942	139	44	complex	complex	ADJ
admet-942	139	45	structures	structure	NOUN
admet-942	139	46	in	in	ADP
admet-942	139	47	heterogeneous	heterogeneous	ADJ
admet-942	139	48	ooc	ooc	NOUN
admet-942	139	49	systems	system	NOUN
admet-942	140	1	[	[	X
admet-942	140	2	58	58	NUM
admet-942	140	3	]	]	PUNCT
admet-942	140	4	.	.	PUNCT
admet-942	141	1	stereolithography	stereolithography	NOUN
admet-942	141	2	creates	create	VERB
admet-942	141	3	a	a	DET
admet-942	141	4	liquid	liquid	ADJ
admet-942	141	5	pattern	pattern	NOUN
admet-942	141	6	that	that	PRON
admet-942	141	7	is	be	AUX
admet-942	141	8	later	later	ADV
admet-942	141	9	polymerized	polymerize	VERB
admet-942	141	10	using	use	VERB
admet-942	141	11	a	a	DET
admet-942	141	12	laser	laser	NOUN
admet-942	141	13	or	or	CCONJ
admet-942	141	14	ultraviolet	ultraviolet	NOUN
admet-942	141	15	(	(	PUNCT
admet-942	141	16	uv	uv	NOUN
admet-942	141	17	)	)	PUNCT
admet-942	141	18	light	light	NOUN
admet-942	141	19	.	.	PUNCT
admet-942	142	1	in	in	ADP
admet-942	142	2	this	this	DET
admet-942	142	3	technique	technique	NOUN
admet-942	142	4	,	,	PUNCT
admet-942	142	5	cell	cell	NOUN
admet-942	142	6	viability	viability	NOUN
admet-942	142	7	may	may	AUX
admet-942	142	8	be	be	AUX
admet-942	142	9	affected	affect	VERB
admet-942	142	10	due	due	ADP
admet-942	142	11	to	to	ADP
admet-942	142	12	the	the	DET
admet-942	142	13	length	length	NOUN
admet-942	142	14	of	of	ADP
admet-942	142	15	time	time	NOUN
admet-942	142	16	of	of	ADP
admet-942	142	17	the	the	DET
admet-942	142	18	process	process	NOUN
admet-942	142	19	and	and	CCONJ
admet-942	142	20	the	the	DET
admet-942	142	21	use	use	NOUN
admet-942	142	22	of	of	ADP
admet-942	142	23	intense	intense	ADJ
admet-942	142	24	radiation	radiation	NOUN
admet-942	142	25	[	[	X
admet-942	142	26	28,57,60	28,57,60	NOUN
admet-942	142	27	]	]	PUNCT
admet-942	142	28	.	.	PUNCT
admet-942	143	1	however	however	ADV
admet-942	143	2	,	,	PUNCT
admet-942	143	3	by	by	ADP
admet-942	143	4	using	use	VERB
admet-942	143	5	stereolithography	stereolithography	NOUN
admet-942	143	6	,	,	PUNCT
admet-942	143	7	vascularized	vascularized	ADJ
admet-942	143	8	channels	channel	NOUN
admet-942	143	9	can	can	AUX
admet-942	143	10	be	be	AUX
admet-942	143	11	integrated	integrate	VERB
admet-942	143	12	and	and	CCONJ
admet-942	143	13	hydrogels	hydrogel	NOUN
admet-942	143	14	can	can	AUX
admet-942	143	15	be	be	AUX
admet-942	143	16	introduced	introduce	VERB
admet-942	143	17	in	in	ADP
admet-942	143	18	an	an	DET
admet-942	143	19	easier	easy	ADJ
admet-942	143	20	way	way	NOUN
admet-942	144	1	[	[	X
admet-942	144	2	57	57	NUM
admet-942	144	3	]	]	PUNCT
admet-942	144	4	.	.	PUNCT
admet-942	145	1	in	in	ADP
admet-942	145	2	the	the	DET
admet-942	145	3	inkjet	inkjet	NOUN
admet-942	145	4	bioprinting	bioprinting	NOUN
admet-942	145	5	technique	technique	NOUN
admet-942	145	6	,	,	PUNCT
admet-942	145	7	drops	drop	NOUN
admet-942	145	8	of	of	ADP
admet-942	145	9	a	a	DET
admet-942	145	10	non	non	ADJ
admet-942	145	11	-	-	ADJ
admet-942	145	12	viscous	viscous	ADJ
admet-942	145	13	bio	bio	NOUN
admet-942	145	14	-	-	ADJ
admet-942	145	15	ink	ink	NOUN
admet-942	145	16	are	be	AUX
admet-942	145	17	released	release	VERB
admet-942	145	18	into	into	ADP
admet-942	145	19	a	a	DET
admet-942	145	20	polymeric	polymeric	ADJ
admet-942	145	21	substrate	substrate	NOUN
admet-942	145	22	obtaining	obtain	VERB
admet-942	145	23	a	a	DET
admet-942	145	24	rapid	rapid	ADJ
admet-942	145	25	formation	formation	NOUN
admet-942	145	26	of	of	ADP
admet-942	145	27	structures	structure	NOUN
admet-942	145	28	by	by	ADP
admet-942	145	29	using	use	VERB
admet-942	145	30	a	a	DET
admet-942	145	31	low	low	ADJ
admet-942	145	32	-	-	PUNCT
admet-942	145	33	cost	cost	NOUN
admet-942	145	34	process	process	NOUN
admet-942	145	35	.	.	PUNCT
admet-942	146	1	there	there	PRON
admet-942	146	2	is	be	VERB
admet-942	146	3	,	,	PUNCT
admet-942	146	4	however	however	ADV
admet-942	146	5	,	,	PUNCT
admet-942	146	6	a	a	DET
admet-942	146	7	lack	lack	NOUN
admet-942	146	8	of	of	ADP
admet-942	146	9	precision	precision	NOUN
admet-942	146	10	in	in	ADP
admet-942	146	11	the	the	DET
admet-942	146	12	direction	direction	NOUN
admet-942	146	13	of	of	ADP
admet-942	146	14	the	the	DET
admet-942	146	15	drop	drop	NOUN
admet-942	146	16	and	and	CCONJ
admet-942	146	17	in	in	ADP
admet-942	146	18	the	the	DET
admet-942	146	19	control	control	NOUN
admet-942	146	20	of	of	ADP
admet-942	146	21	the	the	DET
admet-942	146	22	viscosity	viscosity	NOUN
admet-942	146	23	,	,	PUNCT
admet-942	146	24	which	which	PRON
admet-942	146	25	makes	make	VERB
admet-942	146	26	the	the	DET
admet-942	146	27	construction	construction	NOUN
admet-942	146	28	of	of	ADP
admet-942	146	29	complex	complex	ADJ
admet-942	146	30	designs	design	NOUN
admet-942	146	31	difficult	difficult	ADJ
admet-942	146	32	[	[	X
admet-942	146	33	28,85	28,85	X
admet-942	146	34	]	]	X
admet-942	146	35	.	.	PUNCT
admet-942	147	1	finally	finally	ADV
admet-942	147	2	,	,	PUNCT
admet-942	147	3	laser	laser	NOUN
admet-942	147	4	bioprinting	bioprinting	NOUN
admet-942	147	5	uses	use	VERB
admet-942	147	6	a	a	DET
admet-942	147	7	laser	laser	NOUN
admet-942	147	8	beam	beam	NOUN
admet-942	147	9	to	to	PART
admet-942	147	10	push	push	VERB
admet-942	147	11	a	a	DET
admet-942	147	12	gelled	gelled	ADJ
admet-942	147	13	solution	solution	NOUN
admet-942	147	14	of	of	ADP
admet-942	147	15	cells	cell	NOUN
admet-942	147	16	onto	onto	ADP
admet-942	147	17	a	a	DET
admet-942	147	18	substrate	substrate	NOUN
admet-942	147	19	.	.	PUNCT
admet-942	148	1	this	this	DET
admet-942	148	2	technique	technique	NOUN
admet-942	148	3	offers	offer	VERB
admet-942	148	4	high	high	ADJ
admet-942	148	5	precision	precision	NOUN
admet-942	148	6	in	in	ADP
admet-942	148	7	tissue	tissue	NOUN
admet-942	148	8	production	production	NOUN
admet-942	148	9	and	and	CCONJ
admet-942	148	10	a	a	DET
admet-942	148	11	large	large	ADJ
admet-942	148	12	variety	variety	NOUN
admet-942	148	13	of	of	ADP
admet-942	148	14	materials	material	NOUN
admet-942	148	15	can	can	AUX
admet-942	148	16	be	be	AUX
admet-942	148	17	used	use	VERB
admet-942	148	18	.	.	PUNCT
admet-942	149	1	however	however	ADV
admet-942	149	2	,	,	PUNCT
admet-942	149	3	cells	cell	NOUN
admet-942	149	4	viability	viability	NOUN
admet-942	149	5	can	can	AUX
admet-942	149	6	be	be	AUX
admet-942	149	7	affected	affect	VERB
admet-942	149	8	by	by	ADP
admet-942	149	9	the	the	DET
admet-942	149	10	high	high	ADJ
admet-942	149	11	temperatures	temperature	NOUN
admet-942	149	12	produced	produce	VERB
admet-942	149	13	by	by	ADP
admet-942	149	14	the	the	DET
admet-942	149	15	laser	laser	NOUN
admet-942	149	16	during	during	ADP
admet-942	149	17	the	the	DET
admet-942	149	18	long	long	ADJ
admet-942	149	19	processing	processing	NOUN
admet-942	149	20	time	time	NOUN
admet-942	149	21	[	[	X
admet-942	149	22	1,58	1,58	X
admet-942	149	23	]	]	X
admet-942	149	24	.	.	PUNCT
admet-942	150	1	cell	cell	NOUN
admet-942	150	2	lines	line	NOUN
admet-942	150	3	obtention	obtention	VERB
admet-942	150	4	the	the	DET
admet-942	150	5	correct	correct	ADJ
admet-942	150	6	selection	selection	NOUN
admet-942	150	7	of	of	ADP
admet-942	150	8	biological	biological	ADJ
admet-942	150	9	sources	source	NOUN
admet-942	150	10	for	for	ADP
admet-942	150	11	the	the	DET
admet-942	150	12	production	production	NOUN
admet-942	150	13	of	of	ADP
admet-942	150	14	cellular	cellular	ADJ
admet-942	150	15	tissues	tissue	NOUN
admet-942	150	16	is	be	AUX
admet-942	150	17	a	a	DET
admet-942	150	18	key	key	ADJ
admet-942	150	19	factor	factor	NOUN
admet-942	150	20	to	to	PART
admet-942	150	21	obtain	obtain	VERB
admet-942	150	22	a	a	DET
admet-942	150	23	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	NOUN
admet-942	150	24	r.	r.	PROPN
admet-942	150	25	vargas	vargas	PROPN
admet-942	150	26	,	,	PUNCT
admet-942	150	27	a.	a.	NOUN
admet-942	150	28	egurbide	egurbide	NOUN
admet-942	150	29	-	-	PUNCT
admet-942	150	30	sifre	sifre	NOUN
admet-942	150	31	and	and	CCONJ
admet-942	150	32	l.	l.	PROPN
admet-942	150	33	medina	medina	PROPN
admet-942	150	34	admet	admet	PROPN
admet-942	150	35	&	&	CCONJ
admet-942	150	36	dmpk	dmpk	PROPN
admet-942	150	37	9(2	9(2	NUM
admet-942	150	38	)	)	PUNCT
admet-942	150	39	(	(	PUNCT
admet-942	150	40	2021	2021	NUM
admet-942	150	41	)	)	PUNCT
admet-942	150	42	111	111	NUM
admet-942	150	43	-	-	SYM
admet-942	150	44	141	141	NUM
admet-942	150	45	118	118	NUM
admet-942	150	46	greater	great	ADJ
admet-942	150	47	similarity	similarity	NOUN
admet-942	150	48	between	between	ADP
admet-942	150	49	occs	occs	NOUN
admet-942	150	50	and	and	CCONJ
admet-942	150	51	human	human	ADJ
admet-942	150	52	tissues	tissue	NOUN
admet-942	150	53	.	.	PUNCT
admet-942	151	1	the	the	DET
admet-942	151	2	choice	choice	NOUN
admet-942	151	3	of	of	ADP
admet-942	151	4	the	the	DET
admet-942	151	5	source	source	NOUN
admet-942	151	6	will	will	AUX
admet-942	151	7	depend	depend	VERB
admet-942	151	8	on	on	ADP
admet-942	151	9	the	the	DET
admet-942	151	10	organ	organ	NOUN
admet-942	151	11	and	and	CCONJ
admet-942	151	12	the	the	DET
admet-942	151	13	genetic	genetic	ADJ
admet-942	151	14	background	background	NOUN
admet-942	151	15	aimed	aim	VERB
admet-942	151	16	to	to	PART
admet-942	151	17	be	be	AUX
admet-942	151	18	studied	study	VERB
admet-942	151	19	[	[	X
admet-942	151	20	2,26,42	2,26,42	NUM
admet-942	151	21	]	]	PUNCT
admet-942	151	22	.	.	PUNCT
admet-942	152	1	both	both	DET
admet-942	152	2	primary	primary	ADJ
admet-942	152	3	tissue	tissue	NOUN
admet-942	152	4	cells	cell	NOUN
admet-942	152	5	and	and	CCONJ
admet-942	152	6	immortalized	immortalize	VERB
admet-942	152	7	lines	line	NOUN
admet-942	152	8	can	can	AUX
admet-942	152	9	be	be	AUX
admet-942	152	10	used	use	VERB
admet-942	152	11	for	for	ADP
admet-942	152	12	these	these	DET
admet-942	152	13	purposes	purpose	NOUN
admet-942	152	14	,	,	PUNCT
admet-942	152	15	although	although	SCONJ
admet-942	152	16	the	the	DET
admet-942	152	17	latter	latter	ADJ
admet-942	152	18	may	may	AUX
admet-942	152	19	show	show	VERB
admet-942	152	20	more	more	ADJ
admet-942	152	21	difficulties	difficulty	NOUN
admet-942	152	22	performing	perform	VERB
admet-942	152	23	the	the	DET
admet-942	152	24	physiological	physiological	ADJ
admet-942	152	25	functions	function	NOUN
admet-942	152	26	of	of	ADP
admet-942	152	27	primary	primary	ADJ
admet-942	152	28	cells	cell	NOUN
admet-942	152	29	[	[	X
admet-942	152	30	42	42	NUM
admet-942	152	31	]	]	PUNCT
admet-942	152	32	.	.	PUNCT
admet-942	153	1	numerous	numerous	ADJ
admet-942	153	2	authors	author	NOUN
admet-942	153	3	have	have	AUX
admet-942	153	4	cited	cite	VERB
admet-942	153	5	the	the	DET
admet-942	153	6	use	use	NOUN
admet-942	153	7	of	of	ADP
admet-942	153	8	induced	induced	ADJ
admet-942	153	9	pluripotent	pluripotent	ADJ
admet-942	153	10	stem	stem	NOUN
admet-942	153	11	cells	cell	NOUN
admet-942	153	12	(	(	PUNCT
admet-942	153	13	ipscs	ipsc	NOUN
admet-942	153	14	)	)	PUNCT
admet-942	153	15	for	for	ADP
admet-942	153	16	regenerative	regenerative	ADJ
admet-942	153	17	medicine	medicine	NOUN
admet-942	153	18	,	,	PUNCT
admet-942	153	19	drug	drug	NOUN
admet-942	153	20	discovery	discovery	NOUN
admet-942	153	21	and	and	CCONJ
admet-942	153	22	disease	disease	NOUN
admet-942	153	23	modelling	model	VERB
admet-942	153	24	[	[	X
admet-942	153	25	2,3,5,42,74,86–91	2,3,5,42,74,86–91	NUM
admet-942	153	26	]	]	PUNCT
admet-942	153	27	.	.	PUNCT
admet-942	154	1	these	these	DET
admet-942	154	2	cells	cell	NOUN
admet-942	154	3	show	show	VERB
admet-942	154	4	an	an	DET
admet-942	154	5	extraordinary	extraordinary	ADJ
admet-942	154	6	organizational	organizational	ADJ
admet-942	154	7	capacity	capacity	NOUN
admet-942	154	8	that	that	PRON
admet-942	154	9	allows	allow	VERB
admet-942	154	10	them	they	PRON
admet-942	154	11	to	to	PART
admet-942	154	12	be	be	AUX
admet-942	154	13	modelled	model	VERB
admet-942	154	14	to	to	ADP
admet-942	154	15	any	any	DET
admet-942	154	16	physiological	physiological	ADJ
admet-942	154	17	or	or	CCONJ
admet-942	154	18	pathological	pathological	ADJ
admet-942	154	19	condition	condition	NOUN
admet-942	154	20	[	[	X
admet-942	154	21	2,62,74,86	2,62,74,86	NUM
admet-942	154	22	]	]	PUNCT
admet-942	154	23	.	.	PUNCT
admet-942	155	1	figure	figure	NOUN
admet-942	155	2	3	3	NUM
admet-942	155	3	shows	show	VERB
admet-942	155	4	an	an	DET
admet-942	155	5	outline	outline	NOUN
admet-942	155	6	of	of	ADP
admet-942	155	7	ipscs	ipscs	NOUN
admet-942	155	8	preparation	preparation	NOUN
admet-942	155	9	from	from	ADP
admet-942	155	10	various	various	ADJ
admet-942	155	11	sources	source	NOUN
admet-942	155	12	by	by	ADP
admet-942	155	13	using	use	VERB
admet-942	155	14	different	different	ADJ
admet-942	155	15	reprogramming	reprogramme	VERB
admet-942	155	16	methods	method	NOUN
admet-942	155	17	,	,	PUNCT
admet-942	155	18	including	include	VERB
admet-942	155	19	crisp	crisp	ADJ
admet-942	155	20	-	-	PUNCT
admet-942	155	21	cas9	cas9	NOUN
admet-942	155	22	genome	genome	NOUN
admet-942	155	23	editing	editing	NOUN
admet-942	155	24	[	[	X
admet-942	155	25	92	92	NUM
admet-942	155	26	]	]	PUNCT
admet-942	155	27	.	.	PUNCT
admet-942	156	1	the	the	DET
admet-942	156	2	integration	integration	NOUN
admet-942	156	3	of	of	ADP
admet-942	156	4	ipscs	ipscs	NOUN
admet-942	156	5	in	in	ADP
admet-942	156	6	an	an	DET
admet-942	156	7	ooc	ooc	NOUN
admet-942	156	8	can	can	AUX
admet-942	156	9	be	be	AUX
admet-942	156	10	a	a	DET
admet-942	156	11	useful	useful	ADJ
admet-942	156	12	tool	tool	NOUN
admet-942	156	13	for	for	ADP
admet-942	156	14	personalized	personalized	ADJ
admet-942	156	15	medicine	medicine	NOUN
admet-942	156	16	.	.	PUNCT
admet-942	157	1	these	these	DET
admet-942	157	2	kind	kind	NOUN
admet-942	157	3	of	of	ADP
admet-942	157	4	cells	cell	NOUN
admet-942	157	5	have	have	VERB
admet-942	157	6	a	a	DET
admet-942	157	7	great	great	ADJ
admet-942	157	8	capacity	capacity	NOUN
admet-942	157	9	to	to	PART
admet-942	157	10	induce	induce	VERB
admet-942	157	11	genetic	genetic	ADJ
admet-942	157	12	variability	variability	NOUN
admet-942	157	13	[	[	X
admet-942	157	14	65,90	65,90	NOUN
admet-942	157	15	]	]	PUNCT
admet-942	157	16	and	and	CCONJ
admet-942	157	17	make	make	VERB
admet-942	157	18	it	it	PRON
admet-942	157	19	possible	possible	ADJ
admet-942	157	20	to	to	PART
admet-942	157	21	execute	execute	VERB
admet-942	157	22	specific	specific	ADJ
admet-942	157	23	pathological	pathological	ADJ
admet-942	157	24	evaluations	evaluation	NOUN
admet-942	157	25	,	,	PUNCT
admet-942	157	26	which	which	PRON
admet-942	157	27	can	can	AUX
admet-942	157	28	not	not	PART
admet-942	157	29	be	be	AUX
admet-942	157	30	performed	perform	VERB
admet-942	157	31	through	through	ADP
admet-942	157	32	current	current	ADJ
admet-942	157	33	alternatives	alternative	NOUN
admet-942	157	34	[	[	X
admet-942	157	35	2,5	2,5	NUM
admet-942	157	36	]	]	PUNCT
admet-942	157	37	.	.	PUNCT
admet-942	158	1	musah	musah	NOUN
admet-942	158	2	et	et	PROPN
admet-942	158	3	al	al	PROPN
admet-942	158	4	.	.	PROPN
admet-942	158	5	established	establish	VERB
admet-942	158	6	protocols	protocol	NOUN
admet-942	158	7	to	to	PART
admet-942	158	8	differentiate	differentiate	VERB
admet-942	158	9	ipscs	ipsc	NOUN
admet-942	158	10	into	into	ADP
admet-942	158	11	mature	mature	ADJ
admet-942	158	12	-	-	PUNCT
admet-942	158	13	functional	functional	ADJ
admet-942	158	14	podocytes	podocyte	NOUN
admet-942	158	15	and	and	CCONJ
admet-942	158	16	built	build	VERB
admet-942	158	17	a	a	DET
admet-942	158	18	human	human	ADJ
admet-942	158	19	glomerulus	glomerulus	NOUN
admet-942	158	20	in	in	ADP
admet-942	158	21	a	a	DET
admet-942	158	22	chip	chip	NOUN
admet-942	158	23	with	with	ADP
admet-942	158	24	the	the	DET
admet-942	158	25	aims	aim	NOUN
admet-942	158	26	of	of	ADP
admet-942	158	27	nephrotoxicity	nephrotoxicity	NOUN
admet-942	158	28	screening	screening	NOUN
admet-942	158	29	,	,	PUNCT
admet-942	158	30	therapeutic	therapeutic	ADJ
admet-942	158	31	development	development	NOUN
admet-942	158	32	and	and	CCONJ
admet-942	158	33	the	the	DET
admet-942	158	34	study	study	NOUN
admet-942	158	35	of	of	ADP
admet-942	158	36	kidney	kidney	NOUN
admet-942	158	37	development	development	NOUN
admet-942	158	38	and	and	CCONJ
admet-942	158	39	renal	renal	ADJ
admet-942	158	40	impairment	impairment	NOUN
admet-942	158	41	[	[	X
admet-942	158	42	87	87	NUM
admet-942	158	43	]	]	PUNCT
admet-942	158	44	.	.	PUNCT
admet-942	159	1	smith	smith	PROPN
admet-942	159	2	et	et	PROPN
admet-942	159	3	al	al	PROPN
admet-942	159	4	.	.	PROPN
admet-942	160	1	highlighted	highlight	VERB
admet-942	160	2	methods	method	NOUN
admet-942	160	3	to	to	PART
admet-942	160	4	produce	produce	VERB
admet-942	160	5	ipsc	ipsc	NOUN
admet-942	160	6	-	-	PUNCT
admet-942	160	7	derived	derive	VERB
admet-942	160	8	cardiomyocytes	cardiomyocyte	NOUN
admet-942	160	9	for	for	ADP
admet-942	160	10	efficacy	efficacy	NOUN
admet-942	160	11	/	/	SYM
admet-942	160	12	toxicity	toxicity	NOUN
admet-942	160	13	screening	screening	NOUN
admet-942	160	14	and	and	CCONJ
admet-942	160	15	modelling	modelling	NOUN
admet-942	160	16	of	of	ADP
admet-942	160	17	cardiac	cardiac	ADJ
admet-942	160	18	diseases	disease	NOUN
admet-942	160	19	[	[	X
admet-942	160	20	65	65	NUM
admet-942	160	21	]	]	PUNCT
admet-942	160	22	.	.	PUNCT
admet-942	161	1	moreover	moreover	ADV
admet-942	161	2	,	,	PUNCT
admet-942	161	3	wang	wang	PROPN
admet-942	161	4	et	et	PROPN
admet-942	161	5	al	al	PROPN
admet-942	161	6	.	.	PROPN
admet-942	161	7	developed	develop	VERB
admet-942	161	8	liver	liver	NOUN
admet-942	161	9	organoids	organoid	NOUN
admet-942	161	10	that	that	PRON
admet-942	161	11	showed	show	VERB
admet-942	161	12	hepatic	hepatic	ADJ
admet-942	161	13	functions	function	NOUN
admet-942	161	14	from	from	ADP
admet-942	161	15	ipscs	ipscs	NOUN
admet-942	161	16	[	[	X
admet-942	161	17	89	89	NUM
admet-942	161	18	]	]	PUNCT
admet-942	161	19	.	.	PUNCT
admet-942	162	1	in	in	ADP
admet-942	162	2	another	another	DET
admet-942	162	3	approach	approach	NOUN
admet-942	162	4	,	,	PUNCT
admet-942	162	5	vatine	vatine	NOUN
admet-942	162	6	et	et	PROPN
admet-942	162	7	al	al	PROPN
admet-942	162	8	.	.	PROPN
admet-942	162	9	used	use	VERB
admet-942	162	10	patient	patient	NOUN
admet-942	162	11	-	-	PUNCT
admet-942	162	12	derived	derive	VERB
admet-942	162	13	ipscs	ipscs	NOUN
admet-942	162	14	from	from	ADP
admet-942	162	15	individuals	individual	NOUN
admet-942	162	16	with	with	ADP
admet-942	162	17	neurological	neurological	ADJ
admet-942	162	18	diseases	disease	NOUN
admet-942	162	19	to	to	PART
admet-942	162	20	simulate	simulate	VERB
admet-942	162	21	the	the	DET
admet-942	162	22	disorder	disorder	NOUN
admet-942	162	23	’s	’s	PART
admet-942	162	24	specific	specific	ADJ
admet-942	162	25	physiopathology	physiopathology	NOUN
admet-942	163	1	[	[	X
admet-942	163	2	74	74	NUM
admet-942	163	3	]	]	PUNCT
admet-942	163	4	.	.	PUNCT
admet-942	164	1	figure	figure	NOUN
admet-942	164	2	3	3	NUM
admet-942	164	3	.	.	X
admet-942	164	4	diagram	diagram	PROPN
admet-942	164	5	of	of	ADP
admet-942	164	6	ipsc	ipsc	PROPN
admet-942	164	7	obtainment	obtainment	PROPN
admet-942	164	8	from	from	ADP
admet-942	164	9	i	i	PRON
admet-942	164	10	)	)	PUNCT
admet-942	164	11	fibroblasts	fibroblast	NOUN
admet-942	164	12	,	,	PUNCT
admet-942	164	13	keratinocytes	keratinocyte	NOUN
admet-942	164	14	or	or	CCONJ
admet-942	164	15	melanocytes	melanocyte	NOUN
admet-942	164	16	obtained	obtain	VERB
admet-942	164	17	in	in	ADP
admet-942	164	18	skin	skin	NOUN
admet-942	164	19	biopsy	biopsy	NOUN
admet-942	164	20	,	,	PUNCT
admet-942	164	21	ii	ii	NOUN
admet-942	164	22	)	)	PUNCT
admet-942	165	1	cd34	cd34	PROPN
admet-942	165	2	+	+	NUM
admet-942	165	3	from	from	ADP
admet-942	165	4	blood	blood	NOUN
admet-942	165	5	samples	sample	NOUN
admet-942	165	6	,	,	PUNCT
admet-942	165	7	iii	iii	NOUN
admet-942	165	8	)	)	PUNCT
admet-942	165	9	cd133	cd133	PROPN
admet-942	165	10	+	+	X
admet-942	165	11	from	from	ADP
admet-942	165	12	umbilical	umbilical	ADJ
admet-942	165	13	cord	cord	NOUN
admet-942	165	14	or	or	CCONJ
admet-942	165	15	iv	iv	X
admet-942	165	16	)	)	PUNCT
admet-942	165	17	multipotent	multipotent	NOUN
admet-942	165	18	cell	cell	NOUN
admet-942	165	19	from	from	ADP
admet-942	165	20	adipose	adipose	ADJ
admet-942	165	21	tissue	tissue	NOUN
admet-942	165	22	;	;	PUNCT
admet-942	165	23	ipsc	ipsc	PROPN
admet-942	165	24	reprogrammed	reprogramme	VERB
admet-942	165	25	towards	towards	ADP
admet-942	165	26	pluripotent	pluripotent	ADJ
admet-942	165	27	cells	cell	NOUN
admet-942	165	28	through	through	ADP
admet-942	165	29	different	different	ADJ
admet-942	165	30	induction	induction	NOUN
admet-942	165	31	mechanisms	mechanism	NOUN
admet-942	165	32	such	such	ADJ
admet-942	165	33	as	as	ADP
admet-942	165	34	:	:	PUNCT
admet-942	165	35	v	v	ADJ
admet-942	165	36	)	)	PUNCT
admet-942	165	37	microrna	microrna	PROPN
admet-942	165	38	delivery	delivery	PROPN
admet-942	165	39	,	,	PUNCT
admet-942	165	40	vi	vi	NOUN
admet-942	165	41	)	)	PUNCT
admet-942	165	42	viral	viral	ADJ
admet-942	165	43	transfection	transfection	NOUN
admet-942	165	44	,	,	PUNCT
admet-942	165	45	vii	vii	PROPN
admet-942	165	46	)	)	PUNCT
admet-942	165	47	integration	integration	NOUN
admet-942	165	48	vectors	vector	NOUN
admet-942	165	49	or	or	CCONJ
admet-942	165	50	viii	viii	NOUN
admet-942	165	51	)	)	PUNCT
admet-942	165	52	protein	protein	NOUN
admet-942	165	53	transfection	transfection	NOUN
admet-942	165	54	.	.	PUNCT
admet-942	166	1	adapted	adapt	VERB
admet-942	166	2	from	from	ADP
admet-942	166	3	[	[	X
admet-942	166	4	40	40	NUM
admet-942	166	5	]	]	PUNCT
admet-942	166	6	under	under	ADP
admet-942	166	7	terms	term	NOUN
admet-942	166	8	of	of	ADP
admet-942	166	9	the	the	DET
admet-942	166	10	creative	creative	ADJ
admet-942	166	11	commons	common	NOUN
admet-942	166	12	attribution	attribution	NOUN
admet-942	166	13	license	license	NOUN
admet-942	166	14	.	.	PUNCT
admet-942	167	1	copyright	copyright	NOUN
admet-942	167	2	(	(	PUNCT
admet-942	167	3	2017	2017	NUM
admet-942	167	4	)	)	PUNCT
admet-942	167	5	.	.	PUNCT
admet-942	168	1	applications	application	NOUN
admet-942	168	2	oocs	ooc	NOUN
admet-942	168	3	are	be	AUX
admet-942	168	4	currently	currently	ADV
admet-942	168	5	used	use	VERB
admet-942	168	6	in	in	ADP
admet-942	168	7	preclinical	preclinical	ADJ
admet-942	168	8	phases	phase	NOUN
admet-942	168	9	as	as	ADP
admet-942	168	10	a	a	DET
admet-942	168	11	complement	complement	NOUN
admet-942	168	12	to	to	ADP
admet-942	168	13	animal	animal	NOUN
admet-942	168	14	models	model	NOUN
admet-942	168	15	and	and	CCONJ
admet-942	168	16	cell	cell	NOUN
admet-942	168	17	cultures	culture	NOUN
admet-942	168	18	[	[	X
admet-942	168	19	1,3	1,3	NUM
admet-942	168	20	]	]	X
admet-942	168	21	.	.	PUNCT
admet-942	169	1	2d	2d	NUM
admet-942	169	2	models	model	NOUN
admet-942	169	3	can	can	AUX
admet-942	169	4	not	not	PART
admet-942	169	5	be	be	AUX
admet-942	169	6	used	use	VERB
admet-942	169	7	for	for	ADP
admet-942	169	8	drug	drug	NOUN
admet-942	169	9	evaluation	evaluation	NOUN
admet-942	169	10	in	in	ADP
admet-942	169	11	terms	term	NOUN
admet-942	169	12	of	of	ADP
admet-942	169	13	metabolic	metabolic	NOUN
admet-942	169	14	activity	activity	NOUN
admet-942	169	15	,	,	PUNCT
admet-942	169	16	efficacy	efficacy	NOUN
admet-942	169	17	or	or	CCONJ
admet-942	169	18	systemic	systemic	ADJ
admet-942	169	19	toxicity	toxicity	NOUN
admet-942	169	20	[	[	X
admet-942	169	21	31,42,43,63	31,42,43,63	NUM
admet-942	169	22	]	]	PUNCT
admet-942	169	23	.	.	PUNCT
admet-942	170	1	nevertheless	nevertheless	ADV
admet-942	170	2	,	,	PUNCT
admet-942	170	3	oocs	ooc	NOUN
admet-942	170	4	have	have	VERB
admet-942	170	5	the	the	DET
admet-942	170	6	potential	potential	NOUN
admet-942	170	7	to	to	PART
admet-942	170	8	replace	replace	VERB
admet-942	170	9	traditional	traditional	ADJ
admet-942	170	10	experimental	experimental	ADJ
admet-942	170	11	models	model	NOUN
admet-942	170	12	,	,	PUNCT
admet-942	170	13	as	as	SCONJ
admet-942	170	14	they	they	PRON
admet-942	170	15	have	have	AUX
admet-942	170	16	shown	show	VERB
admet-942	170	17	better	well	ADV
admet-942	170	18	in	in	ADP
admet-942	170	19	vivo	vivo	NOUN
admet-942	170	20	/	/	SYM
admet-942	170	21	in	in	X
admet-942	170	22	vitro	vitro	X
admet-942	170	23	extrapolation	extrapolation	NOUN
admet-942	171	1	[	[	X
admet-942	171	2	6,51,93	6,51,93	NUM
admet-942	171	3	]	]	PUNCT
admet-942	171	4	and	and	CCONJ
admet-942	171	5	potentially	potentially	ADV
admet-942	171	6	represent	represent	VERB
admet-942	171	7	a	a	DET
admet-942	171	8	more	more	ADV
admet-942	171	9	favorable	favorable	ADJ
admet-942	171	10	admet	admet	NOUN
admet-942	171	11	&	&	CCONJ
admet-942	171	12	dmpk	dmpk	PROPN
admet-942	171	13	9(2	9(2	NUM
admet-942	171	14	)	)	PUNCT
admet-942	171	15	(	(	PUNCT
admet-942	171	16	2021	2021	NUM
admet-942	171	17	)	)	PUNCT
admet-942	171	18	111	111	NUM
admet-942	171	19	-	-	SYM
admet-942	171	20	141	141	NUM
admet-942	171	21	organ	organ	NOUN
admet-942	171	22	-	-	PUNCT
admet-942	171	23	on	on	ADP
admet-942	171	24	-	-	PUNCT
admet-942	171	25	a	a	DET
admet-942	171	26	-	-	PUNCT
admet-942	171	27	chip	chip	NOUN
admet-942	171	28	systems	system	NOUN
admet-942	171	29	for	for	ADP
admet-942	171	30	new	new	ADJ
admet-942	171	31	drugs	drug	NOUN
admet-942	171	32	development	development	NOUN
admet-942	171	33	doi	doi	PROPN
admet-942	171	34	:	:	PUNCT
admet-942	171	35	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	171	36	119	119	NUM
admet-942	171	37	risk	risk	NOUN
admet-942	171	38	/	/	SYM
admet-942	171	39	benefit	benefit	NOUN
admet-942	171	40	value	value	NOUN
admet-942	171	41	in	in	ADP
admet-942	171	42	drug	drug	NOUN
admet-942	171	43	research	research	NOUN
admet-942	171	44	and	and	CCONJ
admet-942	171	45	development	development	NOUN
admet-942	171	46	[	[	X
admet-942	171	47	18	18	NUM
admet-942	171	48	]	]	PUNCT
admet-942	171	49	.	.	PUNCT
admet-942	172	1	these	these	DET
admet-942	172	2	systems	system	NOUN
admet-942	172	3	present	present	VERB
admet-942	172	4	outstanding	outstanding	ADJ
admet-942	172	5	features	feature	NOUN
admet-942	172	6	such	such	ADJ
admet-942	172	7	as	as	ADP
admet-942	172	8	the	the	DET
admet-942	172	9	chance	chance	NOUN
admet-942	172	10	to	to	PART
admet-942	172	11	simulate	simulate	VERB
admet-942	172	12	dynamic	dynamic	ADJ
admet-942	172	13	multi	multi	ADJ
admet-942	172	14	-	-	ADJ
admet-942	172	15	organ	organ	ADJ
admet-942	172	16	environment	environment	NOUN
admet-942	173	1	[	[	X
admet-942	173	2	1,2,81,94	1,2,81,94	X
admet-942	173	3	]	]	PUNCT
admet-942	173	4	and	and	CCONJ
admet-942	173	5	to	to	PART
admet-942	173	6	replace	replace	VERB
admet-942	173	7	the	the	DET
admet-942	173	8	use	use	NOUN
admet-942	173	9	of	of	ADP
admet-942	173	10	humans	human	NOUN
admet-942	173	11	in	in	ADP
admet-942	173	12	some	some	DET
admet-942	173	13	phases	phase	NOUN
admet-942	173	14	of	of	ADP
admet-942	173	15	clinical	clinical	ADJ
admet-942	173	16	studies	study	NOUN
admet-942	173	17	[	[	X
admet-942	173	18	80	80	NUM
admet-942	173	19	]	]	PUNCT
admet-942	173	20	.	.	PUNCT
admet-942	174	1	tables	table	NOUN
admet-942	174	2	3	3	NUM
admet-942	174	3	and	and	CCONJ
admet-942	174	4	4	4	NUM
admet-942	174	5	summarize	summarize	VERB
admet-942	174	6	some	some	DET
admet-942	174	7	examples	example	NOUN
admet-942	174	8	of	of	ADP
admet-942	174	9	the	the	DET
admet-942	174	10	applications	application	NOUN
admet-942	174	11	of	of	ADP
admet-942	174	12	ooc	ooc	NOUN
admet-942	174	13	technologies	technology	NOUN
admet-942	174	14	for	for	ADP
admet-942	174	15	organs	organ	NOUN
admet-942	174	16	,	,	PUNCT
admet-942	174	17	systems	system	NOUN
admet-942	174	18	and	and	CCONJ
admet-942	174	19	pathophysiological	pathophysiological	ADJ
admet-942	174	20	conditions	condition	NOUN
admet-942	174	21	.	.	PUNCT
admet-942	175	1	the	the	DET
admet-942	175	2	following	follow	VERB
admet-942	175	3	sections	section	NOUN
admet-942	175	4	point	point	VERB
admet-942	175	5	out	out	ADP
admet-942	175	6	additional	additional	ADJ
admet-942	175	7	features	feature	NOUN
admet-942	175	8	for	for	ADP
admet-942	175	9	some	some	PRON
admet-942	175	10	of	of	ADP
admet-942	175	11	the	the	DET
admet-942	175	12	most	most	ADV
admet-942	175	13	advanced	advanced	ADJ
admet-942	175	14	applications	application	NOUN
admet-942	175	15	with	with	ADP
admet-942	175	16	the	the	DET
admet-942	175	17	greatest	great	ADJ
admet-942	175	18	impact	impact	NOUN
admet-942	175	19	on	on	ADP
admet-942	175	20	academic	academic	ADJ
admet-942	175	21	production	production	NOUN
admet-942	175	22	.	.	PUNCT
admet-942	176	1	table	table	NOUN
admet-942	176	2	3	3	NUM
admet-942	176	3	.	.	X
admet-942	177	1	overview	overview	NOUN
admet-942	177	2	of	of	ADP
admet-942	177	3	some	some	DET
admet-942	177	4	functionalities	functionality	NOUN
admet-942	177	5	and	and	CCONJ
admet-942	177	6	applications	application	NOUN
admet-942	177	7	of	of	ADP
admet-942	177	8	organs	organ	NOUN
admet-942	177	9	or	or	CCONJ
admet-942	177	10	systems	system	NOUN
admet-942	177	11	on	on	ADP
admet-942	177	12	a	a	DET
admet-942	177	13	chip	chip	NOUN
admet-942	177	14	.	.	PUNCT
admet-942	178	1	modified	modify	VERB
admet-942	178	2	from	from	ADP
admet-942	178	3	[	[	X
admet-942	178	4	1,2	1,2	NUM
admet-942	178	5	]	]	PUNCT
admet-942	178	6	.	.	PUNCT
admet-942	179	1	organ	organ	NOUN
admet-942	179	2	or	or	CCONJ
admet-942	179	3	system	system	VERB
admet-942	179	4	main	main	ADJ
admet-942	179	5	components	component	NOUN
admet-942	179	6	of	of	ADP
admet-942	179	7	the	the	DET
admet-942	179	8	ooc	ooc	NOUN
admet-942	179	9	functionality	functionality	NOUN
admet-942	179	10	preclinical	preclinical	ADJ
admet-942	179	11	application	application	NOUN
admet-942	179	12	references	reference	NOUN
admet-942	179	13	heart	heart	NOUN
admet-942	179	14	contractible	contractible	ADJ
admet-942	179	15	3d	3d	NUM
admet-942	179	16	conformation	conformation	NOUN
admet-942	179	17	.	.	PUNCT
admet-942	180	1	incorporation	incorporation	NOUN
admet-942	180	2	of	of	ADP
admet-942	180	3	structural	structural	ADJ
admet-942	180	4	proteins	protein	NOUN
admet-942	180	5	.	.	PUNCT
admet-942	181	1	electrical	electrical	ADJ
admet-942	181	2	stimulation	stimulation	NOUN
admet-942	181	3	.	.	PUNCT
admet-942	182	1	regulated	regulate	VERB
admet-942	182	2	mitochondrial	mitochondrial	ADJ
admet-942	182	3	distribution	distribution	NOUN
admet-942	182	4	.	.	PUNCT
admet-942	183	1	simulation	simulation	NOUN
admet-942	183	2	of	of	ADP
admet-942	183	3	frank	frank	ADJ
admet-942	183	4	-	-	PUNCT
admet-942	183	5	starling	starle	VERB
admet-942	183	6	mechanics	mechanic	NOUN
admet-942	183	7	in	in	ADP
admet-942	183	8	cardiomyocytes	cardiomyocyte	NOUN
admet-942	183	9	.	.	PUNCT
admet-942	184	1	demonstration	demonstration	NOUN
admet-942	184	2	of	of	ADP
admet-942	184	3	auxotonic	auxotonic	ADJ
admet-942	184	4	contractions	contraction	NOUN
admet-942	184	5	.	.	PUNCT
admet-942	185	1	cardiotoxicity	cardiotoxicity	NOUN
admet-942	185	2	tests	test	NOUN
admet-942	185	3	.	.	PUNCT
admet-942	186	1	study	study	NOUN
admet-942	186	2	of	of	ADP
admet-942	186	3	physiological	physiological	ADJ
admet-942	186	4	phenomena	phenomenon	NOUN
admet-942	186	5	involved	involve	VERB
admet-942	186	6	in	in	ADP
admet-942	186	7	cardiac	cardiac	ADJ
admet-942	186	8	functioning	functioning	NOUN
admet-942	186	9	.	.	PUNCT
admet-942	187	1	[	[	X
admet-942	187	2	2][4][6][7][11][18	2][4][6][7][11][18	X
admet-942	187	3	]	]	X
admet-942	188	1	[	[	X
admet-942	188	2	21	21	NUM
admet-942	188	3	]	]	X
admet-942	189	1	[	[	X
admet-942	189	2	44][71][70	44][71][70	X
admet-942	189	3	]	]	X
admet-942	190	1	[	[	X
admet-942	190	2	65	65	NUM
admet-942	190	3	]	]	X
admet-942	191	1	[	[	X
admet-942	191	2	82	82	NUM
admet-942	191	3	]	]	X
admet-942	192	1	[	[	X
admet-942	192	2	84][95	84][95	X
admet-942	192	3	]	]	X
admet-942	192	4	[	[	X
admet-942	192	5	96	96	NUM
admet-942	192	6	]	]	X
admet-942	192	7	kidney	kidney	NOUN
admet-942	192	8	barriers	barrier	VERB
admet-942	192	9	formation	formation	NOUN
admet-942	192	10	.	.	PUNCT
admet-942	193	1	permeability	permeability	NOUN
admet-942	193	2	modulation	modulation	NOUN
admet-942	193	3	with	with	ADP
admet-942	193	4	different	different	ADJ
admet-942	193	5	types	type	NOUN
admet-942	193	6	of	of	ADP
admet-942	193	7	proteins	protein	NOUN
admet-942	193	8	.	.	PUNCT
admet-942	194	1	generation	generation	NOUN
admet-942	194	2	of	of	ADP
admet-942	194	3	structural	structural	ADJ
admet-942	194	4	proteins	protein	NOUN
admet-942	194	5	.	.	PUNCT
admet-942	195	1	functional	functional	ADJ
admet-942	195	2	assessment	assessment	NOUN
admet-942	195	3	under	under	ADP
admet-942	195	4	mechanical	mechanical	ADJ
admet-942	195	5	stress	stress	NOUN
admet-942	195	6	conditions	condition	NOUN
admet-942	195	7	.	.	PUNCT
admet-942	196	1	separation	separation	NOUN
admet-942	196	2	of	of	ADP
admet-942	196	3	tubular	tubular	ADJ
admet-942	196	4	flow	flow	NOUN
admet-942	196	5	and	and	CCONJ
admet-942	196	6	interstitial	interstitial	ADJ
admet-942	196	7	fluids	fluid	NOUN
admet-942	196	8	.	.	PUNCT
admet-942	196	9	selective	selective	ADJ
admet-942	196	10	filtration	filtration	NOUN
admet-942	196	11	in	in	ADP
admet-942	196	12	kidney	kidney	NOUN
admet-942	196	13	models	model	NOUN
admet-942	196	14	.	.	PUNCT
admet-942	197	1	simulation	simulation	NOUN
admet-942	197	2	of	of	ADP
admet-942	197	3	type	type	NOUN
admet-942	197	4	ii	ii	PROPN
admet-942	197	5	diabetes	diabetes	NOUN
admet-942	197	6	mellitus	mellitus	NOUN
admet-942	197	7	nephropathy	nephropathy	NOUN
admet-942	197	8	.	.	PUNCT
admet-942	198	1	evaluation	evaluation	NOUN
admet-942	198	2	of	of	ADP
admet-942	198	3	drug	drug	NOUN
admet-942	198	4	-	-	PUNCT
admet-942	198	5	induced	induce	VERB
admet-942	198	6	nephrotoxicity	nephrotoxicity	NOUN
admet-942	198	7	.	.	PUNCT
admet-942	199	1	research	research	NOUN
admet-942	199	2	on	on	ADP
admet-942	199	3	the	the	DET
admet-942	199	4	physiological	physiological	ADJ
admet-942	199	5	role	role	NOUN
admet-942	199	6	of	of	ADP
admet-942	199	7	specific	specific	ADJ
admet-942	199	8	proteins	protein	NOUN
admet-942	199	9	.	.	PUNCT
admet-942	200	1	study	study	NOUN
admet-942	200	2	of	of	ADP
admet-942	200	3	viral	viral	ADJ
admet-942	200	4	infections	infection	NOUN
admet-942	200	5	.	.	PUNCT
admet-942	201	1	[	[	X
admet-942	201	2	1][2][4][13	1][2][4][13	X
admet-942	201	3	]	]	X
admet-942	201	4	[	[	X
admet-942	201	5	21	21	NUM
admet-942	201	6	]	]	X
admet-942	201	7	[	[	X
admet-942	201	8	45][87][75][84	45][87][75][84	X
admet-942	201	9	]	]	X
admet-942	201	10	[	[	X
admet-942	201	11	97][98	97][98	NUM
admet-942	201	12	]	]	PUNCT
admet-942	201	13	lung	lung	NOUN
admet-942	201	14	simulation	simulation	NOUN
admet-942	201	15	of	of	ADP
admet-942	201	16	the	the	DET
admet-942	201	17	alveolus	alveolus	ADJ
admet-942	201	18	/	/	SYM
admet-942	201	19	capillary	capillary	ADJ
admet-942	201	20	interface	interface	NOUN
admet-942	201	21	.	.	PUNCT
admet-942	202	1	modulation	modulation	NOUN
admet-942	202	2	of	of	ADP
admet-942	202	3	cell	cell	NOUN
admet-942	202	4	permeability	permeability	NOUN
admet-942	202	5	.	.	PUNCT
admet-942	203	1	presence	presence	NOUN
admet-942	203	2	of	of	ADP
admet-942	203	3	intercellular	intercellular	ADJ
admet-942	203	4	proteins	protein	NOUN
admet-942	203	5	.	.	PUNCT
admet-942	204	1	simulation	simulation	NOUN
admet-942	204	2	of	of	ADP
admet-942	204	3	air	air	NOUN
admet-942	204	4	-	-	PUNCT
admet-942	204	5	water	water	NOUN
admet-942	204	6	interfaces	interface	NOUN
admet-942	204	7	with	with	ADP
admet-942	204	8	or	or	CCONJ
admet-942	204	9	without	without	ADP
admet-942	204	10	the	the	DET
admet-942	204	11	presence	presence	NOUN
admet-942	204	12	of	of	ADP
admet-942	204	13	airflow	airflow	NOUN
admet-942	204	14	.	.	PUNCT
admet-942	205	1	breathing	breathing	NOUN
admet-942	205	2	simulation	simulation	NOUN
admet-942	205	3	using	use	VERB
admet-942	205	4	cyclic	cyclic	ADJ
admet-942	205	5	mechanical	mechanical	ADJ
admet-942	205	6	stress	stress	NOUN
admet-942	205	7	.	.	PUNCT
admet-942	206	1	evaluation	evaluation	NOUN
admet-942	206	2	of	of	ADP
admet-942	206	3	resistance	resistance	NOUN
admet-942	206	4	mechanisms	mechanism	NOUN
admet-942	206	5	in	in	ADP
admet-942	206	6	lung	lung	NOUN
admet-942	206	7	cancer	cancer	NOUN
admet-942	206	8	.	.	PUNCT
admet-942	207	1	lung	lung	NOUN
admet-942	207	2	proteins	protein	NOUN
admet-942	207	3	study	study	NOUN
admet-942	207	4	.	.	PUNCT
admet-942	208	1	metabolism	metabolism	NOUN
admet-942	208	2	of	of	ADP
admet-942	208	3	drugs	drug	NOUN
admet-942	208	4	.	.	PUNCT
admet-942	209	1	systemic	systemic	ADJ
admet-942	209	2	toxicity	toxicity	NOUN
admet-942	209	3	studies	study	NOUN
admet-942	209	4	.	.	PUNCT
admet-942	210	1	[	[	X
admet-942	210	2	1][13][18][21][29	1][13][18][21][29	X
admet-942	210	3	]	]	X
admet-942	210	4	[	[	X
admet-942	210	5	42][52][54][71	42][52][54][71	X
admet-942	210	6	]	]	PUNCT
admet-942	211	1	[	[	X
admet-942	211	2	99][100	99][100	X
admet-942	211	3	]	]	X
admet-942	212	1	[	[	X
admet-942	212	2	101	101	NUM
admet-942	212	3	]	]	PUNCT
admet-942	212	4	gut	gut	NOUN
admet-942	212	5	differentiation	differentiation	NOUN
admet-942	212	6	of	of	ADP
admet-942	212	7	the	the	DET
admet-942	212	8	intestinal	intestinal	ADJ
admet-942	212	9	epithelium	epithelium	NOUN
admet-942	212	10	.	.	PUNCT
admet-942	213	1	reproduction	reproduction	NOUN
admet-942	213	2	of	of	ADP
admet-942	213	3	peristalsis	peristalsis	NOUN
admet-942	213	4	.	.	PUNCT
admet-942	214	1	incorporation	incorporation	NOUN
admet-942	214	2	of	of	ADP
admet-942	214	3	extracellular	extracellular	ADJ
admet-942	214	4	proteins	protein	NOUN
admet-942	214	5	.	.	PUNCT
admet-942	215	1	reproduction	reproduction	NOUN
admet-942	215	2	of	of	ADP
admet-942	215	3	intracellular	intracellular	ADJ
admet-942	215	4	and	and	CCONJ
admet-942	215	5	paracellular	paracellular	ADJ
admet-942	215	6	transport	transport	NOUN
admet-942	215	7	.	.	PUNCT
admet-942	216	1	microbiota	microbiota	NOUN
admet-942	216	2	interactions	interaction	NOUN
admet-942	216	3	studies	study	NOUN
admet-942	216	4	.	.	PUNCT
admet-942	217	1	pathogenic	pathogenic	ADJ
admet-942	217	2	bacteria	bacteria	NOUN
admet-942	217	3	models	model	NOUN
admet-942	217	4	.	.	PUNCT
admet-942	218	1	study	study	NOUN
admet-942	218	2	of	of	ADP
admet-942	218	3	viral	viral	ADJ
admet-942	218	4	infections	infection	NOUN
admet-942	218	5	.	.	PUNCT
admet-942	219	1	simulation	simulation	NOUN
admet-942	219	2	of	of	ADP
admet-942	219	3	barrier	barrier	NOUN
admet-942	219	4	function	function	NOUN
admet-942	219	5	loss	loss	NOUN
admet-942	219	6	.	.	PUNCT
admet-942	220	1	drug	drug	NOUN
admet-942	220	2	absorption	absorption	NOUN
admet-942	220	3	and	and	CCONJ
admet-942	220	4	metabolism	metabolism	NOUN
admet-942	220	5	evaluation	evaluation	NOUN
admet-942	220	6	.	.	PUNCT
admet-942	221	1	[	[	X
admet-942	221	2	1][2][4][7][8][13	1][2][4][7][8][13	X
admet-942	221	3	]	]	PUNCT
admet-942	222	1	[	[	X
admet-942	222	2	31][51][52][69	31][51][52][69	X
admet-942	222	3	]	]	X
admet-942	223	1	[	[	X
admet-942	223	2	72][102][103	72][102][103	X
admet-942	223	3	]	]	X
admet-942	224	1	[	[	X
admet-942	224	2	104	104	X
admet-942	224	3	]	]	PUNCT
admet-942	225	1	[	[	X
admet-942	225	2	105][106	105][106	X
admet-942	225	3	]	]	X
admet-942	225	4	liver	liver	NOUN
admet-942	225	5	3d	3d	NUM
admet-942	225	6	cultures	culture	NOUN
admet-942	225	7	with	with	ADP
admet-942	225	8	specific	specific	ADJ
admet-942	225	9	liver	liver	NOUN
admet-942	225	10	substructures	substructure	NOUN
admet-942	225	11	.	.	PUNCT
admet-942	226	1	kupffer	kupffer	NOUN
admet-942	226	2	cell	cell	NOUN
admet-942	226	3	incorporation	incorporation	NOUN
admet-942	226	4	.	.	PUNCT
admet-942	227	1	incorporation	incorporation	NOUN
admet-942	227	2	of	of	ADP
admet-942	227	3	structural	structural	ADJ
admet-942	227	4	proteins	protein	NOUN
admet-942	227	5	.	.	PUNCT
admet-942	228	1	secretion	secretion	NOUN
admet-942	228	2	and	and	CCONJ
admet-942	228	3	production	production	NOUN
admet-942	228	4	of	of	ADP
admet-942	228	5	high	high	ADJ
admet-942	228	6	levels	level	NOUN
admet-942	228	7	of	of	ADP
admet-942	228	8	urea	urea	NOUN
admet-942	228	9	and	and	CCONJ
admet-942	228	10	albumin	albumin	ADJ
admet-942	228	11	.	.	PUNCT
admet-942	229	1	enzymatic	enzymatic	ADJ
admet-942	229	2	activity	activity	NOUN
admet-942	229	3	.	.	PUNCT
admet-942	230	1	production	production	NOUN
admet-942	230	2	of	of	ADP
admet-942	230	3	bile	bile	NOUN
admet-942	230	4	and	and	CCONJ
admet-942	230	5	formation	formation	NOUN
admet-942	230	6	of	of	ADP
admet-942	230	7	gallbladder	gallbladder	NOUN
admet-942	230	8	.	.	PUNCT
admet-942	231	1	drug	drug	NOUN
admet-942	231	2	metabolism	metabolism	NOUN
admet-942	231	3	studies	study	NOUN
admet-942	231	4	.	.	PUNCT
admet-942	232	1	hepatotoxic	hepatotoxic	ADJ
admet-942	232	2	effect	effect	NOUN
admet-942	232	3	of	of	ADP
admet-942	232	4	drugs	drug	NOUN
admet-942	232	5	and	and	CCONJ
admet-942	232	6	toxicity	toxicity	NOUN
admet-942	232	7	effects	effect	NOUN
admet-942	232	8	on	on	ADP
admet-942	232	9	other	other	ADJ
admet-942	232	10	organs	organ	NOUN
admet-942	232	11	(	(	PUNCT
admet-942	232	12	including	include	VERB
admet-942	232	13	the	the	DET
admet-942	232	14	influence	influence	NOUN
admet-942	232	15	of	of	ADP
admet-942	232	16	liver	liver	NOUN
admet-942	232	17	metabolites	metabolite	NOUN
admet-942	232	18	)	)	PUNCT
admet-942	232	19	.	.	PUNCT
admet-942	233	1	glycogenesis	glycogenesis	PROPN
admet-942	233	2	studies	study	NOUN
admet-942	233	3	(	(	PUNCT
admet-942	233	4	and	and	CCONJ
admet-942	233	5	inhibition	inhibition	NOUN
admet-942	233	6	by	by	ADP
admet-942	233	7	drugs	drug	NOUN
admet-942	233	8	)	)	PUNCT
admet-942	233	9	.	.	PUNCT
admet-942	234	1	fatty	fatty	VERB
admet-942	234	2	liver	liver	NOUN
admet-942	234	3	drug	drug	NOUN
admet-942	234	4	development	development	NOUN
admet-942	234	5	.	.	PUNCT
admet-942	235	1	[	[	X
admet-942	235	2	2][4][11][13][43	2][4][11][13][43	X
admet-942	235	3	]	]	X
admet-942	236	1	[	[	X
admet-942	236	2	51][67][68][71	51][67][68][71	X
admet-942	236	3	]	]	X
admet-942	236	4	[	[	X
admet-942	236	5	89	89	NUM
admet-942	236	6	]	]	X
admet-942	236	7	[	[	X
admet-942	236	8	99][104][107	99][104][107	X
admet-942	236	9	]	]	X
admet-942	236	10	[	[	X
admet-942	236	11	108	108	NUM
admet-942	236	12	]	]	PUNCT
admet-942	236	13	brain	brain	NOUN
admet-942	236	14	/	/	SYM
admet-942	236	15	central	central	ADJ
admet-942	236	16	nervous	nervous	ADJ
admet-942	236	17	system	system	NOUN
admet-942	236	18	blood	blood	NOUN
admet-942	236	19	-	-	PUNCT
admet-942	236	20	brain	brain	NOUN
admet-942	236	21	barrier	barrier	NOUN
admet-942	236	22	(	(	PUNCT
admet-942	236	23	bbb	bbb	NOUN
admet-942	236	24	)	)	PUNCT
admet-942	236	25	formation	formation	NOUN
admet-942	236	26	in	in	ADP
admet-942	236	27	the	the	DET
admet-942	236	28	presence	presence	NOUN
admet-942	236	29	of	of	ADP
admet-942	236	30	astrocytes	astrocyte	NOUN
admet-942	236	31	and	and	CCONJ
admet-942	236	32	neurons	neuron	NOUN
admet-942	236	33	,	,	PUNCT
admet-942	236	34	and	and	CCONJ
admet-942	236	35	with	with	ADP
admet-942	236	36	modulated	modulate	VERB
admet-942	236	37	cell	cell	NOUN
admet-942	236	38	permeability	permeability	NOUN
admet-942	236	39	.	.	PUNCT
admet-942	237	1	formation	formation	NOUN
admet-942	237	2	of	of	ADP
admet-942	237	3	tubular	tubular	ADJ
admet-942	237	4	vessels	vessel	NOUN
admet-942	237	5	.	.	PUNCT
admet-942	238	1	structural	structural	ADJ
admet-942	238	2	protein	protein	NOUN
admet-942	238	3	incorporation	incorporation	NOUN
admet-942	238	4	.	.	PUNCT
admet-942	239	1	brain	brain	NOUN
admet-942	239	2	folding	folding	NOUN
admet-942	239	3	.	.	PUNCT
admet-942	240	1	replication	replication	NOUN
admet-942	240	2	of	of	ADP
admet-942	240	3	the	the	DET
admet-942	240	4	neurovascular	neurovascular	ADJ
admet-942	240	5	unit	unit	NOUN
admet-942	240	6	.	.	PUNCT
admet-942	241	1	study	study	NOUN
admet-942	241	2	of	of	ADP
admet-942	241	3	neurodegenerative	neurodegenerative	ADJ
admet-942	241	4	diseases	disease	NOUN
admet-942	241	5	.	.	PUNCT
admet-942	242	1	inflammation	inflammation	NOUN
admet-942	242	2	studies	study	NOUN
admet-942	242	3	by	by	ADP
admet-942	242	4	lipopolysaccharide	lipopolysaccharide	ADJ
admet-942	242	5	endotoxins	endotoxin	NOUN
admet-942	242	6	or	or	CCONJ
admet-942	242	7	others	other	NOUN
admet-942	242	8	.	.	PUNCT
admet-942	243	1	study	study	NOUN
admet-942	243	2	of	of	ADP
admet-942	243	3	the	the	DET
admet-942	243	4	influence	influence	NOUN
admet-942	243	5	of	of	ADP
admet-942	243	6	drugs	drug	NOUN
admet-942	243	7	in	in	ADP
admet-942	243	8	the	the	DET
admet-942	243	9	prenatal	prenatal	ADJ
admet-942	243	10	period	period	NOUN
admet-942	243	11	.	.	PUNCT
admet-942	244	1	determination	determination	NOUN
admet-942	244	2	of	of	ADP
admet-942	244	3	permeability	permeability	NOUN
admet-942	244	4	of	of	ADP
admet-942	244	5	drugs	drug	NOUN
admet-942	244	6	and	and	CCONJ
admet-942	244	7	nanoparticles	nanoparticle	NOUN
admet-942	244	8	through	through	ADP
admet-942	244	9	bbb	bbb	PROPN
admet-942	244	10	.	.	PUNCT
admet-942	245	1	[	[	X
admet-942	245	2	1][2][4][21][48	1][2][4][21][48	ADP
admet-942	245	3	]	]	X
admet-942	246	1	[	[	X
admet-942	246	2	49][64][49][74	49][64][49][74	X
admet-942	246	3	]	]	X
admet-942	247	1	[	[	X
admet-942	247	2	75][88][109	75][88][109	X
admet-942	247	3	]	]	PUNCT
admet-942	247	4	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	ADV
admet-942	247	5	r.	r.	PROPN
admet-942	247	6	vargas	vargas	PROPN
admet-942	247	7	,	,	PUNCT
admet-942	247	8	a.	a.	NOUN
admet-942	247	9	egurbide	egurbide	NOUN
admet-942	247	10	-	-	PUNCT
admet-942	247	11	sifre	sifre	NOUN
admet-942	247	12	and	and	CCONJ
admet-942	247	13	l.	l.	PROPN
admet-942	247	14	medina	medina	PROPN
admet-942	247	15	admet	admet	PROPN
admet-942	247	16	&	&	CCONJ
admet-942	247	17	dmpk	dmpk	PROPN
admet-942	247	18	9(2	9(2	NUM
admet-942	247	19	)	)	PUNCT
admet-942	247	20	(	(	PUNCT
admet-942	247	21	2021	2021	NUM
admet-942	247	22	)	)	PUNCT
admet-942	247	23	111	111	NUM
admet-942	247	24	-	-	SYM
admet-942	247	25	141	141	NUM
admet-942	247	26	120	120	NUM
admet-942	247	27	table	table	NOUN
admet-942	247	28	3	3	NUM
admet-942	247	29	.	.	NUM
admet-942	247	30	continued	continue	VERB
admet-942	247	31	…	…	PUNCT
admet-942	247	32	organ	organ	NOUN
admet-942	247	33	or	or	CCONJ
admet-942	247	34	system	system	VERB
admet-942	247	35	main	main	ADJ
admet-942	247	36	components	component	NOUN
admet-942	247	37	of	of	ADP
admet-942	247	38	the	the	DET
admet-942	247	39	ooc	ooc	NOUN
admet-942	247	40	functionality	functionality	NOUN
admet-942	247	41	preclinical	preclinical	ADJ
admet-942	247	42	application	application	NOUN
admet-942	247	43	references	reference	NOUN
admet-942	247	44	placenta	placenta	VERB
admet-942	247	45	formation	formation	NOUN
admet-942	247	46	of	of	ADP
admet-942	247	47	the	the	DET
admet-942	247	48	placental	placental	ADJ
admet-942	247	49	barrier	barrier	NOUN
admet-942	247	50	.	.	PUNCT
admet-942	248	1	permeability	permeability	NOUN
admet-942	248	2	modulation	modulation	NOUN
admet-942	248	3	for	for	ADP
admet-942	248	4	high	high	ADJ
admet-942	248	5	molecular	molecular	ADJ
admet-942	248	6	weight	weight	NOUN
admet-942	248	7	proteins	protein	NOUN
admet-942	248	8	.	.	PUNCT
admet-942	249	1	division	division	NOUN
admet-942	249	2	of	of	ADP
admet-942	249	3	fetal	fetal	ADJ
admet-942	249	4	and	and	CCONJ
admet-942	249	5	maternal	maternal	ADJ
admet-942	249	6	chambers	chamber	NOUN
admet-942	249	7	with	with	ADP
admet-942	249	8	fluid	fluid	ADJ
admet-942	249	9	flow	flow	NOUN
admet-942	249	10	.	.	PUNCT
admet-942	250	1	transfer	transfer	NOUN
admet-942	250	2	of	of	ADP
admet-942	250	3	nutrients	nutrient	NOUN
admet-942	250	4	and	and	CCONJ
admet-942	250	5	glucose	glucose	NOUN
admet-942	250	6	to	to	ADP
admet-942	250	7	fetal	fetal	ADJ
admet-942	250	8	compartments	compartment	NOUN
admet-942	250	9	.	.	PUNCT
admet-942	251	1	evaluation	evaluation	NOUN
admet-942	251	2	of	of	ADP
admet-942	251	3	placental	placental	NOUN
admet-942	251	4	responses	response	NOUN
admet-942	251	5	.	.	PUNCT
admet-942	252	1	simulation	simulation	NOUN
admet-942	252	2	of	of	ADP
admet-942	252	3	drug	drug	NOUN
admet-942	252	4	transport	transport	NOUN
admet-942	252	5	across	across	ADP
admet-942	252	6	the	the	DET
admet-942	252	7	placenta	placenta	NOUN
admet-942	252	8	using	use	VERB
admet-942	252	9	cancer	cancer	NOUN
admet-942	252	10	-	-	PUNCT
admet-942	252	11	derived	derive	VERB
admet-942	252	12	cells	cell	NOUN
admet-942	252	13	.	.	PUNCT
admet-942	253	1	study	study	NOUN
admet-942	253	2	of	of	ADP
admet-942	253	3	the	the	DET
admet-942	253	4	influence	influence	NOUN
admet-942	253	5	of	of	ADP
admet-942	253	6	drugs	drug	NOUN
admet-942	253	7	in	in	ADP
admet-942	253	8	the	the	DET
admet-942	253	9	prenatal	prenatal	ADJ
admet-942	253	10	period	period	NOUN
admet-942	253	11	.	.	PUNCT
admet-942	254	1	[	[	X
admet-942	254	2	1][21][110][111	1][21][110][111	NUM
admet-942	254	3	]	]	PUNCT
admet-942	254	4	adipose	adipose	ADP
admet-942	254	5	tissue	tissue	NOUN
admet-942	254	6	creation	creation	NOUN
admet-942	254	7	of	of	ADP
admet-942	254	8	adipose	adipose	ADJ
admet-942	254	9	spheres	sphere	NOUN
admet-942	254	10	that	that	PRON
admet-942	254	11	simulate	simulate	VERB
admet-942	254	12	adipose	adipose	PRON
admet-942	254	13	tissue	tissue	NOUN
admet-942	254	14	in	in	ADP
admet-942	254	15	vivo	vivo	NOUN
admet-942	254	16	.	.	PUNCT
admet-942	255	1	vascular	vascular	ADJ
admet-942	255	2	-	-	PUNCT
admet-942	255	3	adipose	adipose	NOUN
admet-942	255	4	tissue	tissue	NOUN
admet-942	255	5	interface	interface	NOUN
admet-942	255	6	.	.	PUNCT
admet-942	256	1	fatty	fatty	NOUN
admet-942	256	2	acid	acid	NOUN
admet-942	256	3	absorption	absorption	NOUN
admet-942	256	4	.	.	PUNCT
admet-942	257	1	glucose	glucose	NOUN
admet-942	257	2	uptake	uptake	ADJ
admet-942	257	3	studies	study	NOUN
admet-942	257	4	.	.	PUNCT
admet-942	258	1	obesity	obesity	NOUN
admet-942	258	2	models	model	NOUN
admet-942	258	3	.	.	PUNCT
admet-942	259	1	development	development	NOUN
admet-942	259	2	of	of	ADP
admet-942	259	3	cell	cell	NOUN
admet-942	259	4	retention	retention	NOUN
admet-942	259	5	methods	method	NOUN
admet-942	259	6	.	.	PUNCT
admet-942	260	1	[	[	X
admet-942	260	2	1][96][102	1][96][102	NUM
admet-942	260	3	]	]	PUNCT
admet-942	260	4	retina	retina	VERB
admet-942	260	5	retinal	retinal	ADJ
admet-942	260	6	pigment	pigment	NOUN
admet-942	260	7	formation	formation	NOUN
admet-942	260	8	.	.	PUNCT
admet-942	261	1	development	development	NOUN
admet-942	261	2	of	of	ADP
admet-942	261	3	the	the	DET
admet-942	261	4	epitheliumchoroid	epitheliumchoroid	ADJ
admet-942	261	5	structure	structure	NOUN
admet-942	261	6	.	.	PUNCT
admet-942	262	1	presence	presence	NOUN
admet-942	262	2	of	of	ADP
admet-942	262	3	structural	structural	ADJ
admet-942	262	4	proteins	protein	NOUN
admet-942	262	5	.	.	PUNCT
admet-942	263	1	pathologies	pathology	NOUN
admet-942	263	2	models	model	NOUN
admet-942	263	3	.	.	PUNCT
admet-942	264	1	reproduction	reproduction	NOUN
admet-942	264	2	of	of	ADP
admet-942	264	3	imaging	imaging	NOUN
admet-942	264	4	processes	process	NOUN
admet-942	264	5	.	.	PUNCT
admet-942	265	1	[	[	X
admet-942	265	2	1][62][112][113	1][62][112][113	NUM
admet-942	265	3	]	]	X
admet-942	265	4	muscle	muscle	NOUN
admet-942	265	5	contractile	contractile	NOUN
admet-942	265	6	units	unit	NOUN
admet-942	265	7	through	through	ADP
admet-942	265	8	chemical	chemical	NOUN
admet-942	265	9	or	or	CCONJ
admet-942	265	10	electrical	electrical	ADJ
admet-942	265	11	stimuli	stimulus	NOUN
admet-942	265	12	.	.	PUNCT
admet-942	266	1	evaluation	evaluation	NOUN
admet-942	266	2	of	of	ADP
admet-942	266	3	the	the	DET
admet-942	266	4	effect	effect	NOUN
admet-942	266	5	and	and	CCONJ
admet-942	266	6	toxicity	toxicity	NOUN
admet-942	266	7	of	of	ADP
admet-942	266	8	drugs	drug	NOUN
admet-942	266	9	.	.	PUNCT
admet-942	267	1	study	study	NOUN
admet-942	267	2	of	of	ADP
admet-942	267	3	degenerative	degenerative	ADJ
admet-942	267	4	diseases	disease	NOUN
admet-942	267	5	and	and	CCONJ
admet-942	267	6	muscle	muscle	NOUN
admet-942	267	7	physiology	physiology	NOUN
admet-942	267	8	.	.	PUNCT
admet-942	268	1	[	[	X
admet-942	268	2	2][114][115	2][114][115	NUM
admet-942	268	3	]	]	SYM
admet-942	268	4	others	other	NOUN
admet-942	268	5	immune	immune	ADJ
admet-942	268	6	system	system	NOUN
admet-942	268	7	[	[	X
admet-942	268	8	50,71	50,71	NOUN
admet-942	268	9	]	]	X
admet-942	268	10	,	,	PUNCT
admet-942	268	11	bone	bone	NOUN
admet-942	269	1	[	[	X
admet-942	269	2	116,117	116,117	NUM
admet-942	269	3	]	]	PUNCT
admet-942	269	4	,	,	PUNCT
admet-942	270	1	breast	breast	NOUN
admet-942	270	2	tissue	tissue	NOUN
admet-942	271	1	[	[	X
admet-942	271	2	118,119	118,119	NUM
admet-942	271	3	]	]	PUNCT
admet-942	271	4	,	,	PUNCT
admet-942	271	5	pancreas	pancrea	NOUN
admet-942	271	6	[	[	X
admet-942	271	7	120,121	120,121	NUM
admet-942	271	8	]	]	PUNCT
admet-942	271	9	,	,	PUNCT
admet-942	271	10	bladder	bladder	NOUN
admet-942	271	11	,	,	PUNCT
admet-942	271	12	reproductive	reproductive	ADJ
admet-942	271	13	tract	tract	NOUN
admet-942	271	14	[	[	X
admet-942	271	15	104	104	NUM
admet-942	271	16	]	]	PUNCT
admet-942	271	17	,	,	PUNCT
admet-942	271	18	skin	skin	NOUN
admet-942	271	19	[	[	X
admet-942	271	20	13	13	NUM
admet-942	271	21	]	]	PUNCT
admet-942	271	22	.	.	PUNCT
admet-942	272	1	heart	heart	NOUN
admet-942	272	2	-	-	PUNCT
admet-942	272	3	on	on	ADP
admet-942	272	4	-	-	PUNCT
admet-942	272	5	a	a	DET
admet-942	272	6	-	-	PUNCT
admet-942	272	7	chip	chip	NOUN
admet-942	272	8	cardiotoxicity	cardiotoxicity	NOUN
admet-942	272	9	is	be	AUX
admet-942	272	10	one	one	NUM
admet-942	272	11	of	of	ADP
admet-942	272	12	the	the	DET
admet-942	272	13	most	most	ADV
admet-942	272	14	common	common	ADJ
admet-942	272	15	causes	cause	NOUN
admet-942	272	16	of	of	ADP
admet-942	272	17	drug	drug	NOUN
admet-942	272	18	failures	failure	NOUN
admet-942	272	19	in	in	ADP
admet-942	272	20	phase	phase	NOUN
admet-942	272	21	i	i	PRON
admet-942	272	22	clinical	clinical	ADJ
admet-942	272	23	trials	trial	NOUN
admet-942	272	24	[	[	X
admet-942	272	25	13	13	NUM
admet-942	272	26	]	]	PUNCT
admet-942	272	27	,	,	PUNCT
admet-942	272	28	highlighting	highlight	VERB
admet-942	272	29	the	the	DET
admet-942	272	30	necessity	necessity	NOUN
admet-942	272	31	of	of	ADP
admet-942	272	32	more	more	ADV
admet-942	272	33	accurate	accurate	ADJ
admet-942	272	34	prediction	prediction	NOUN
admet-942	272	35	models	model	NOUN
admet-942	272	36	for	for	ADP
admet-942	272	37	a	a	DET
admet-942	272	38	preclinical	preclinical	ADJ
admet-942	272	39	screening	screening	NOUN
admet-942	272	40	.	.	PUNCT
admet-942	273	1	an	an	DET
admet-942	273	2	interesting	interesting	ADJ
admet-942	273	3	number	number	NOUN
admet-942	273	4	of	of	ADP
admet-942	273	5	ooc	ooc	NOUN
admet-942	273	6	models	model	NOUN
admet-942	273	7	simulating	simulate	VERB
admet-942	273	8	the	the	DET
admet-942	273	9	human	human	ADJ
admet-942	273	10	heart	heart	NOUN
admet-942	273	11	have	have	AUX
admet-942	273	12	been	be	AUX
admet-942	273	13	developed	develop	VERB
admet-942	273	14	with	with	ADP
admet-942	273	15	different	different	ADJ
admet-942	273	16	levels	level	NOUN
admet-942	273	17	of	of	ADP
admet-942	273	18	complexity	complexity	NOUN
admet-942	273	19	.	.	PUNCT
admet-942	274	1	its	its	PRON
admet-942	274	2	main	main	ADJ
admet-942	274	3	application	application	NOUN
admet-942	274	4	is	be	AUX
admet-942	274	5	centered	center	VERB
admet-942	274	6	on	on	ADP
admet-942	274	7	the	the	DET
admet-942	274	8	evaluation	evaluation	NOUN
admet-942	274	9	of	of	ADP
admet-942	274	10	the	the	DET
admet-942	274	11	contractile	contractile	NOUN
admet-942	274	12	and	and	CCONJ
admet-942	274	13	rhythmic	rhythmic	ADJ
admet-942	274	14	functions	function	NOUN
admet-942	274	15	[	[	X
admet-942	274	16	6,7,13,18,44,122	6,7,13,18,44,122	NUM
admet-942	274	17	]	]	PUNCT
admet-942	274	18	.	.	PUNCT
admet-942	275	1	the	the	DET
admet-942	275	2	ooc	ooc	NOUN
admet-942	275	3	application	application	NOUN
admet-942	275	4	for	for	ADP
admet-942	275	5	heart	heart	NOUN
admet-942	275	6	reproduction	reproduction	NOUN
admet-942	275	7	can	can	AUX
admet-942	275	8	be	be	AUX
admet-942	275	9	a	a	DET
admet-942	275	10	powerful	powerful	ADJ
admet-942	275	11	tool	tool	NOUN
admet-942	275	12	in	in	ADP
admet-942	275	13	the	the	DET
admet-942	275	14	preclinical	preclinical	ADJ
admet-942	275	15	evaluation	evaluation	NOUN
admet-942	275	16	of	of	ADP
admet-942	275	17	a	a	DET
admet-942	275	18	drug	drug	NOUN
admet-942	275	19	,	,	PUNCT
admet-942	275	20	as	as	SCONJ
admet-942	275	21	it	it	PRON
admet-942	275	22	allows	allow	VERB
admet-942	275	23	to	to	PART
admet-942	275	24	connect	connect	VERB
admet-942	275	25	the	the	DET
admet-942	275	26	heart	heart	NOUN
admet-942	275	27	with	with	ADP
admet-942	275	28	the	the	DET
admet-942	275	29	lungs	lung	NOUN
admet-942	275	30	and	and	CCONJ
admet-942	275	31	the	the	DET
admet-942	275	32	liver	liver	NOUN
admet-942	275	33	and	and	CCONJ
admet-942	275	34	to	to	PART
admet-942	275	35	detect	detect	VERB
admet-942	275	36	toxic	toxic	ADJ
admet-942	275	37	reactions	reaction	NOUN
admet-942	275	38	that	that	PRON
admet-942	275	39	may	may	AUX
admet-942	275	40	be	be	AUX
admet-942	275	41	absent	absent	ADJ
admet-942	275	42	when	when	SCONJ
admet-942	275	43	the	the	DET
admet-942	275	44	drug	drug	NOUN
admet-942	275	45	is	be	AUX
admet-942	275	46	assessed	assess	VERB
admet-942	275	47	in	in	ADP
admet-942	275	48	an	an	DET
admet-942	275	49	isolated	isolated	ADJ
admet-942	275	50	tissue	tissue	NOUN
admet-942	276	1	[	[	X
admet-942	276	2	1,11,65	1,11,65	NUM
admet-942	276	3	]	]	PUNCT
admet-942	276	4	.	.	PUNCT
admet-942	277	1	schroer	schroer	PROPN
admet-942	277	2	et	et	PROPN
admet-942	277	3	al	al	PROPN
admet-942	277	4	.	.	PROPN
admet-942	277	5	published	publish	VERB
admet-942	277	6	a	a	DET
admet-942	277	7	work	work	NOUN
admet-942	277	8	focused	focus	VERB
admet-942	277	9	on	on	ADP
admet-942	277	10	contractile	contractile	NOUN
admet-942	277	11	characteristics	characteristic	NOUN
admet-942	277	12	and	and	CCONJ
admet-942	277	13	parameter	parameter	NOUN
admet-942	277	14	determination	determination	NOUN
admet-942	277	15	for	for	ADP
admet-942	277	16	personalized	personalized	ADJ
admet-942	277	17	cardiac	cardiac	ADJ
admet-942	277	18	cell	cell	NOUN
admet-942	277	19	tissues	tissue	NOUN
admet-942	278	1	[	[	X
admet-942	278	2	95	95	NUM
admet-942	278	3	]	]	PUNCT
admet-942	278	4	.	.	PUNCT
admet-942	279	1	the	the	DET
admet-942	279	2	heart	heart	NOUN
admet-942	279	3	-	-	PUNCT
admet-942	279	4	on	on	ADP
admet-942	279	5	-	-	PUNCT
admet-942	279	6	a	a	DET
admet-942	279	7	-	-	PUNCT
admet-942	279	8	chip	chip	NOUN
admet-942	279	9	developed	develop	VERB
admet-942	279	10	by	by	ADP
admet-942	279	11	abulaiti	abulaiti	PROPN
admet-942	279	12	et	et	PROPN
admet-942	279	13	al	al	PROPN
admet-942	279	14	,	,	PUNCT
admet-942	279	15	(	(	PUNCT
admet-942	279	16	figure	figure	NOUN
admet-942	279	17	4	4	NUM
admet-942	279	18	)	)	PUNCT
admet-942	279	19	allowed	allow	VERB
admet-942	279	20	the	the	DET
admet-942	279	21	evaluation	evaluation	NOUN
admet-942	279	22	of	of	ADP
admet-942	279	23	heart	heart	NOUN
admet-942	279	24	tissue	tissue	NOUN
admet-942	279	25	function	function	NOUN
admet-942	279	26	and	and	CCONJ
admet-942	279	27	visualization	visualization	NOUN
admet-942	279	28	of	of	ADP
admet-942	279	29	cardiac	cardiac	ADJ
admet-942	279	30	micro	micro	NOUN
admet-942	279	31	-	-	ADJ
admet-942	279	32	tissue	tissue	ADJ
admet-942	279	33	kinetics	kinetic	NOUN
admet-942	279	34	by	by	ADP
admet-942	279	35	monitoring	monitor	VERB
admet-942	279	36	the	the	DET
admet-942	279	37	displacement	displacement	NOUN
admet-942	279	38	of	of	ADP
admet-942	279	39	fluorescent	fluorescent	ADJ
admet-942	279	40	particles	particle	NOUN
admet-942	279	41	incorporated	incorporate	VERB
admet-942	279	42	within	within	ADP
admet-942	279	43	one	one	NUM
admet-942	279	44	of	of	ADP
admet-942	279	45	the	the	DET
admet-942	279	46	device	device	NOUN
admet-942	279	47	’s	’s	PART
admet-942	279	48	compartments	compartment	NOUN
admet-942	279	49	through	through	ADP
admet-942	279	50	fluorescence	fluorescence	NOUN
admet-942	279	51	microscopy	microscopy	NOUN
admet-942	279	52	,	,	PUNCT
admet-942	279	53	flow	flow	NOUN
admet-942	279	54	cytometry	cytometry	NOUN
admet-942	279	55	and	and	CCONJ
admet-942	279	56	high	high	ADJ
admet-942	279	57	resolution	resolution	NOUN
admet-942	279	58	cameras	camera	NOUN
admet-942	279	59	[	[	X
admet-942	279	60	82	82	NUM
admet-942	279	61	]	]	PUNCT
admet-942	279	62	.	.	PUNCT
admet-942	280	1	kidney	kidney	NOUN
admet-942	280	2	-	-	PUNCT
admet-942	280	3	on	on	ADP
admet-942	280	4	-	-	PUNCT
admet-942	280	5	a	a	DET
admet-942	280	6	-	-	PUNCT
admet-942	280	7	chip	chip	NOUN
admet-942	280	8	the	the	DET
admet-942	280	9	kidney	kidney	NOUN
admet-942	280	10	is	be	AUX
admet-942	280	11	the	the	DET
admet-942	280	12	main	main	ADJ
admet-942	280	13	organ	organ	NOUN
admet-942	280	14	for	for	ADP
admet-942	280	15	hemofiltration	hemofiltration	NOUN
admet-942	280	16	,	,	PUNCT
admet-942	280	17	it	it	PRON
admet-942	280	18	is	be	AUX
admet-942	280	19	involved	involve	VERB
admet-942	280	20	in	in	ADP
admet-942	280	21	waste	waste	NOUN
admet-942	280	22	excretion	excretion	NOUN
admet-942	280	23	and	and	CCONJ
admet-942	280	24	it	it	PRON
admet-942	280	25	is	be	AUX
admet-942	280	26	indispensable	indispensable	ADJ
admet-942	280	27	for	for	ADP
admet-942	280	28	homeostasis	homeostasis	NOUN
admet-942	280	29	.	.	PUNCT
admet-942	281	1	therefore	therefore	ADV
admet-942	281	2	,	,	PUNCT
admet-942	281	3	the	the	DET
admet-942	281	4	study	study	NOUN
admet-942	281	5	of	of	ADP
admet-942	281	6	the	the	DET
admet-942	281	7	renal	renal	ADJ
admet-942	281	8	function	function	NOUN
admet-942	281	9	by	by	ADP
admet-942	281	10	using	use	VERB
admet-942	281	11	ooc	ooc	NOUN
admet-942	281	12	can	can	AUX
admet-942	281	13	be	be	AUX
admet-942	281	14	a	a	DET
admet-942	281	15	very	very	ADV
admet-942	281	16	interesting	interesting	ADJ
admet-942	281	17	tool	tool	NOUN
admet-942	281	18	for	for	ADP
admet-942	281	19	drug	drug	NOUN
admet-942	281	20	development	development	NOUN
admet-942	281	21	and	and	CCONJ
admet-942	281	22	for	for	ADP
admet-942	281	23	the	the	DET
admet-942	281	24	determination	determination	NOUN
admet-942	281	25	of	of	ADP
admet-942	281	26	the	the	DET
admet-942	281	27	systemic	systemic	ADJ
admet-942	281	28	safety	safety	NOUN
admet-942	281	29	profile	profile	NOUN
admet-942	281	30	of	of	ADP
admet-942	281	31	drugs	drug	NOUN
admet-942	281	32	[	[	X
admet-942	281	33	2	2	NUM
admet-942	281	34	]	]	PUNCT
admet-942	281	35	.	.	PUNCT
admet-942	282	1	the	the	DET
admet-942	282	2	greatest	great	ADJ
admet-942	282	3	challenge	challenge	NOUN
admet-942	282	4	in	in	ADP
admet-942	282	5	developing	develop	VERB
admet-942	282	6	functional	functional	ADJ
admet-942	282	7	kidneys	kidney	NOUN
admet-942	282	8	-	-	PUNCT
admet-942	282	9	on	on	ADP
admet-942	282	10	-	-	PUNCT
admet-942	282	11	a	a	DET
admet-942	282	12	-	-	PUNCT
admet-942	282	13	chip	chip	NOUN
admet-942	282	14	is	be	AUX
admet-942	282	15	the	the	DET
admet-942	282	16	simulation	simulation	NOUN
admet-942	282	17	of	of	ADP
admet-942	282	18	the	the	DET
admet-942	282	19	tubular	tubular	ADJ
admet-942	282	20	structure	structure	NOUN
admet-942	282	21	with	with	ADP
admet-942	282	22	a	a	DET
admet-942	282	23	sophisticated	sophisticated	ADJ
admet-942	282	24	control	control	NOUN
admet-942	282	25	of	of	ADP
admet-942	282	26	the	the	DET
admet-942	282	27	physical	physical	ADJ
admet-942	282	28	parameters	parameter	NOUN
admet-942	282	29	involved	involve	VERB
admet-942	282	30	in	in	ADP
admet-942	282	31	the	the	DET
admet-942	282	32	glomerular	glomerular	ADJ
admet-942	282	33	filtration	filtration	NOUN
admet-942	282	34	[	[	X
admet-942	282	35	1,2,87	1,2,87	X
admet-942	282	36	]	]	PUNCT
admet-942	282	37	.	.	PUNCT
admet-942	283	1	the	the	DET
admet-942	283	2	introduction	introduction	NOUN
admet-942	283	3	of	of	ADP
admet-942	283	4	an	an	DET
admet-942	283	5	on	on	ADP
admet-942	283	6	-	-	PUNCT
admet-942	283	7	line	line	NOUN
admet-942	283	8	renal	renal	ADJ
admet-942	283	9	function	function	NOUN
admet-942	283	10	detection	detection	NOUN
admet-942	283	11	unit	unit	NOUN
admet-942	283	12	in	in	ADP
admet-942	283	13	the	the	DET
admet-942	283	14	ooc	ooc	NOUN
admet-942	283	15	allows	allow	VERB
admet-942	283	16	compounds	compound	NOUN
admet-942	283	17	at	at	ADP
admet-942	283	18	very	very	ADV
admet-942	283	19	low	low	ADJ
admet-942	283	20	concentrations	concentration	NOUN
admet-942	283	21	to	to	PART
admet-942	283	22	be	be	AUX
admet-942	283	23	detected	detect	VERB
admet-942	283	24	in	in	ADP
admet-942	283	25	the	the	DET
admet-942	283	26	system	system	NOUN
admet-942	283	27	[	[	X
admet-942	283	28	1	1	NUM
admet-942	283	29	]	]	PUNCT
admet-942	283	30	.	.	PUNCT
admet-942	284	1	admet	admet	PROPN
admet-942	284	2	&	&	CCONJ
admet-942	284	3	dmpk	dmpk	PROPN
admet-942	284	4	9(2	9(2	NUM
admet-942	284	5	)	)	PUNCT
admet-942	284	6	(	(	PUNCT
admet-942	284	7	2021	2021	NUM
admet-942	284	8	)	)	PUNCT
admet-942	284	9	111	111	NUM
admet-942	284	10	-	-	SYM
admet-942	284	11	141	141	NUM
admet-942	284	12	organ	organ	NOUN
admet-942	284	13	-	-	PUNCT
admet-942	284	14	on	on	ADP
admet-942	284	15	-	-	PUNCT
admet-942	284	16	a	a	DET
admet-942	284	17	-	-	PUNCT
admet-942	284	18	chip	chip	NOUN
admet-942	284	19	systems	system	NOUN
admet-942	284	20	for	for	ADP
admet-942	284	21	new	new	ADJ
admet-942	284	22	drugs	drug	NOUN
admet-942	284	23	development	development	NOUN
admet-942	284	24	doi	doi	PROPN
admet-942	284	25	:	:	PUNCT
admet-942	284	26	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	284	27	121	121	NUM
admet-942	284	28	figure	figure	NOUN
admet-942	284	29	4	4	NUM
admet-942	284	30	.	.	PUNCT
admet-942	285	1	heart	heart	NOUN
admet-942	285	2	-	-	PUNCT
admet-942	285	3	on	on	ADP
admet-942	285	4	-	-	PUNCT
admet-942	285	5	a	a	DET
admet-942	285	6	-	-	PUNCT
admet-942	285	7	chip	chip	NOUN
admet-942	285	8	for	for	ADP
admet-942	285	9	the	the	DET
admet-942	285	10	evaluation	evaluation	NOUN
admet-942	285	11	of	of	ADP
admet-942	285	12	physiological	physiological	ADJ
admet-942	285	13	parameters	parameter	NOUN
admet-942	285	14	.	.	PUNCT
admet-942	286	1	a	a	DET
admet-942	286	2	)	)	PUNCT
admet-942	286	3	device	device	NOUN
admet-942	286	4	diagram	diagram	NOUN
admet-942	286	5	and	and	CCONJ
admet-942	286	6	structure	structure	NOUN
admet-942	286	7	.	.	PUNCT
admet-942	287	1	graphs	graphs	PROPN
admet-942	287	2	b	b	NOUN
admet-942	287	3	)	)	PUNCT
admet-942	287	4	and	and	CCONJ
admet-942	287	5	c	c	X
admet-942	287	6	)	)	PUNCT
admet-942	287	7	respectively	respectively	ADV
admet-942	287	8	show	show	VERB
admet-942	287	9	the	the	DET
admet-942	287	10	effect	effect	NOUN
admet-942	287	11	of	of	ADP
admet-942	287	12	two	two	NUM
admet-942	287	13	different	different	ADJ
admet-942	287	14	isoprotenol	isoprotenol	ADJ
admet-942	287	15	concentrations	concentration	NOUN
admet-942	287	16	on	on	ADP
admet-942	287	17	the	the	DET
admet-942	287	18	heart	heart	NOUN
admet-942	287	19	rate	rate	NOUN
admet-942	287	20	and	and	CCONJ
admet-942	287	21	the	the	DET
admet-942	287	22	magnitude	magnitude	NOUN
admet-942	287	23	of	of	ADP
admet-942	287	24	contractile	contractile	ADJ
admet-942	287	25	displacement	displacement	NOUN
admet-942	287	26	,	,	PUNCT
admet-942	287	27	compared	compare	VERB
admet-942	287	28	to	to	ADP
admet-942	287	29	no	no	DET
admet-942	287	30	treatment	treatment	NOUN
admet-942	287	31	values	value	NOUN
admet-942	287	32	.	.	PUNCT
admet-942	288	1	adapted	adapt	VERB
admet-942	288	2	from	from	ADP
admet-942	288	3	[	[	X
admet-942	288	4	82	82	NUM
admet-942	288	5	]	]	PUNCT
admet-942	288	6	under	under	ADP
admet-942	288	7	terms	term	NOUN
admet-942	288	8	of	of	ADP
admet-942	288	9	the	the	DET
admet-942	288	10	creative	creative	ADJ
admet-942	288	11	commons	common	NOUN
admet-942	288	12	attribution	attribution	NOUN
admet-942	288	13	license	license	NOUN
admet-942	288	14	.	.	PUNCT
admet-942	289	1	copyright	copyright	NOUN
admet-942	289	2	(	(	PUNCT
admet-942	289	3	2020	2020	NUM
admet-942	289	4	)	)	PUNCT
admet-942	289	5	.	.	PUNCT
admet-942	290	1	some	some	DET
admet-942	290	2	examples	example	NOUN
admet-942	290	3	of	of	ADP
admet-942	290	4	this	this	DET
admet-942	290	5	technology	technology	NOUN
admet-942	290	6	can	can	AUX
admet-942	290	7	be	be	AUX
admet-942	290	8	found	find	VERB
admet-942	290	9	in	in	ADP
admet-942	290	10	the	the	DET
admet-942	290	11	work	work	NOUN
admet-942	290	12	of	of	ADP
admet-942	290	13	yin	yin	PROPN
admet-942	290	14	et	et	PROPN
admet-942	290	15	al	al	PROPN
admet-942	290	16	,	,	PUNCT
admet-942	290	17	who	who	PRON
admet-942	290	18	developed	develop	VERB
admet-942	290	19	a	a	DET
admet-942	290	20	kidney	kidney	NOUN
admet-942	290	21	-	-	PUNCT
admet-942	290	22	on	on	ADP
admet-942	290	23	-	-	PUNCT
admet-942	290	24	achip	achip	NOUN
admet-942	290	25	device	device	NOUN
admet-942	290	26	for	for	ADP
admet-942	290	27	drug	drug	NOUN
admet-942	290	28	screening	screening	NOUN
admet-942	290	29	and	and	CCONJ
admet-942	290	30	nephrotoxicity	nephrotoxicity	NOUN
admet-942	290	31	assessment	assessment	NOUN
admet-942	290	32	(	(	PUNCT
admet-942	290	33	figure	figure	NOUN
admet-942	290	34	5	5	NUM
admet-942	290	35	)	)	PUNCT
admet-942	290	36	.	.	PUNCT
admet-942	291	1	they	they	PRON
admet-942	291	2	achieved	achieve	VERB
admet-942	291	3	tissue	tissue	NOUN
admet-942	291	4	differentiation	differentiation	NOUN
admet-942	291	5	and	and	CCONJ
admet-942	291	6	functionality	functionality	NOUN
admet-942	291	7	by	by	ADP
admet-942	291	8	growing	grow	VERB
admet-942	291	9	the	the	DET
admet-942	291	10	two	two	NUM
admet-942	291	11	cell	cell	NOUN
admet-942	291	12	cultures	culture	NOUN
admet-942	291	13	on	on	ADP
admet-942	291	14	opposite	opposite	ADJ
admet-942	291	15	membranes	membrane	NOUN
admet-942	291	16	,	,	PUNCT
admet-942	291	17	and	and	CCONJ
admet-942	291	18	evaluated	evaluate	VERB
admet-942	291	19	the	the	DET
admet-942	291	20	cell	cell	NOUN
admet-942	291	21	growth	growth	NOUN
admet-942	291	22	and	and	CCONJ
admet-942	291	23	viability	viability	NOUN
admet-942	291	24	using	use	VERB
admet-942	291	25	fluorescent	fluorescent	ADJ
admet-942	291	26	markers	marker	NOUN
admet-942	291	27	[	[	X
admet-942	291	28	97	97	NUM
admet-942	291	29	]	]	PUNCT
admet-942	291	30	.	.	PUNCT
admet-942	292	1	on	on	ADP
admet-942	292	2	the	the	DET
admet-942	292	3	other	other	ADJ
admet-942	292	4	hand	hand	NOUN
admet-942	292	5	,	,	PUNCT
admet-942	292	6	jang	jang	PROPN
admet-942	292	7	et	et	PROPN
admet-942	292	8	al	al	PROPN
admet-942	292	9	.	.	PROPN
admet-942	292	10	built	build	VERB
admet-942	292	11	a	a	DET
admet-942	292	12	system	system	NOUN
admet-942	292	13	for	for	ADP
admet-942	292	14	drug	drug	NOUN
admet-942	292	15	transport	transport	NOUN
admet-942	292	16	and	and	CCONJ
admet-942	292	17	nephrotoxicity	nephrotoxicity	NOUN
admet-942	292	18	assessment	assessment	NOUN
admet-942	292	19	in	in	ADP
admet-942	292	20	preclinical	preclinical	ADJ
admet-942	292	21	phases	phase	NOUN
admet-942	292	22	that	that	PRON
admet-942	292	23	mimicked	mimic	VERB
admet-942	292	24	key	key	ADJ
admet-942	292	25	functions	function	NOUN
admet-942	292	26	of	of	ADP
admet-942	292	27	the	the	DET
admet-942	292	28	human	human	ADJ
admet-942	292	29	kidney	kidney	NOUN
admet-942	292	30	proximal	proximal	ADJ
admet-942	292	31	tubule	tubule	NOUN
admet-942	292	32	.	.	PUNCT
admet-942	293	1	the	the	DET
admet-942	293	2	chips	chip	NOUN
admet-942	293	3	architecture	architecture	NOUN
admet-942	293	4	exposed	expose	VERB
admet-942	293	5	cell	cell	NOUN
admet-942	293	6	layers	layer	NOUN
admet-942	293	7	to	to	ADP
admet-942	293	8	a	a	DET
admet-942	293	9	fluid	fluid	ADJ
admet-942	293	10	shear	shear	NOUN
admet-942	293	11	stress	stress	NOUN
admet-942	293	12	similar	similar	ADJ
admet-942	293	13	of	of	ADP
admet-942	293	14	that	that	PRON
admet-942	293	15	found	find	VERB
admet-942	293	16	in	in	ADP
admet-942	293	17	living	live	VERB
admet-942	293	18	kidney	kidney	NOUN
admet-942	293	19	tubules	tubule	NOUN
admet-942	293	20	,	,	PUNCT
admet-942	293	21	resulting	result	VERB
admet-942	293	22	in	in	ADP
admet-942	293	23	an	an	DET
admet-942	293	24	enhanced	enhanced	ADJ
admet-942	293	25	epithelial	epithelial	ADJ
admet-942	293	26	cell	cell	NOUN
admet-942	293	27	polarization	polarization	NOUN
admet-942	293	28	,	,	PUNCT
admet-942	293	29	differentiation	differentiation	NOUN
admet-942	293	30	and	and	CCONJ
admet-942	293	31	function	function	NOUN
admet-942	293	32	compared	compare	VERB
admet-942	293	33	to	to	ADP
admet-942	293	34	traditional	traditional	ADJ
admet-942	293	35	transwell	transwell	NOUN
admet-942	293	36	culture	culture	NOUN
admet-942	293	37	system	system	NOUN
admet-942	293	38	[	[	X
admet-942	293	39	98	98	NUM
admet-942	293	40	]	]	PUNCT
admet-942	293	41	.	.	PUNCT
admet-942	294	1	wang	wang	PROPN
admet-942	294	2	et	et	PROPN
admet-942	294	3	al	al	PROPN
admet-942	294	4	.	.	PROPN
admet-942	294	5	developed	develop	VERB
admet-942	294	6	a	a	DET
admet-942	294	7	kidney	kidney	NOUN
admet-942	294	8	-	-	PUNCT
admet-942	294	9	on	on	ADP
admet-942	294	10	-	-	PUNCT
admet-942	294	11	a	a	DET
admet-942	294	12	-	-	PUNCT
admet-942	294	13	chip	chip	NOUN
admet-942	294	14	for	for	ADP
admet-942	294	15	the	the	DET
admet-942	294	16	study	study	NOUN
admet-942	294	17	of	of	ADP
admet-942	294	18	virus	virus	NOUN
admet-942	294	19	pathogenic	pathogenic	ADJ
admet-942	294	20	mechanisms	mechanism	NOUN
admet-942	294	21	inducing	induce	VERB
admet-942	294	22	renal	renal	ADJ
admet-942	294	23	infections	infection	NOUN
admet-942	294	24	,	,	PUNCT
admet-942	294	25	which	which	PRON
admet-942	294	26	allowed	allow	VERB
admet-942	294	27	in	in	ADP
admet-942	294	28	-	-	PUNCT
admet-942	294	29	line	line	NOUN
admet-942	294	30	cell	cell	NOUN
admet-942	294	31	characterization	characterization	NOUN
admet-942	294	32	using	use	VERB
admet-942	294	33	confocal	confocal	ADJ
admet-942	294	34	imaging	imaging	NOUN
admet-942	294	35	and	and	CCONJ
admet-942	294	36	scanning	scan	VERB
admet-942	294	37	electron	electron	NOUN
admet-942	294	38	microscope	microscope	NOUN
admet-942	294	39	imaging	imaging	NOUN
admet-942	294	40	[	[	X
admet-942	294	41	45	45	NUM
admet-942	294	42	]	]	PUNCT
admet-942	294	43	.	.	PUNCT
admet-942	295	1	lung	lung	NOUN
admet-942	295	2	-	-	PUNCT
admet-942	295	3	on	on	ADP
admet-942	295	4	-	-	PUNCT
admet-942	295	5	a	a	DET
admet-942	295	6	-	-	PUNCT
admet-942	295	7	chip	chip	NOUN
admet-942	295	8	modern	modern	ADJ
admet-942	295	9	ooc	ooc	NOUN
admet-942	295	10	systems	system	NOUN
admet-942	295	11	are	be	AUX
admet-942	295	12	inspired	inspire	VERB
admet-942	295	13	by	by	ADP
admet-942	295	14	the	the	DET
admet-942	295	15	pioneering	pioneering	ADJ
admet-942	295	16	development	development	NOUN
admet-942	295	17	of	of	ADP
admet-942	295	18	a	a	DET
admet-942	295	19	lung	lung	NOUN
admet-942	295	20	-	-	PUNCT
admet-942	295	21	on	on	ADP
admet-942	295	22	-	-	PUNCT
admet-942	295	23	a	a	DET
admet-942	295	24	-	-	PUNCT
admet-942	295	25	chip	chip	NOUN
admet-942	295	26	.	.	PUNCT
admet-942	296	1	the	the	DET
admet-942	296	2	main	main	ADJ
admet-942	296	3	challenges	challenge	NOUN
admet-942	296	4	for	for	ADP
admet-942	296	5	an	an	DET
admet-942	296	6	accurate	accurate	ADJ
admet-942	296	7	lung	lung	NOUN
admet-942	296	8	function	function	NOUN
admet-942	296	9	are	be	AUX
admet-942	296	10	the	the	DET
admet-942	296	11	generation	generation	NOUN
admet-942	296	12	of	of	ADP
admet-942	296	13	biomechanical	biomechanical	ADJ
admet-942	296	14	ventilation	ventilation	NOUN
admet-942	296	15	,	,	PUNCT
admet-942	296	16	reproduction	reproduction	NOUN
admet-942	296	17	of	of	ADP
admet-942	296	18	lung	lung	NOUN
admet-942	296	19	mucosa	mucosa	NOUN
admet-942	296	20	and	and	CCONJ
admet-942	296	21	the	the	DET
admet-942	296	22	capability	capability	NOUN
admet-942	296	23	to	to	PART
admet-942	296	24	overcome	overcome	VERB
admet-942	296	25	the	the	DET
admet-942	296	26	possible	possible	ADJ
admet-942	296	27	prothrombotic	prothrombotic	ADJ
admet-942	296	28	interference	interference	NOUN
admet-942	296	29	and	and	CCONJ
admet-942	296	30	the	the	DET
admet-942	296	31	rigidity	rigidity	NOUN
admet-942	296	32	of	of	ADP
admet-942	296	33	the	the	DET
admet-942	296	34	simulated	simulate	VERB
admet-942	296	35	lung	lung	NOUN
admet-942	296	36	tissue	tissue	NOUN
admet-942	296	37	[	[	X
admet-942	296	38	1,13	1,13	NUM
admet-942	296	39	]	]	PUNCT
admet-942	296	40	.	.	PUNCT
admet-942	297	1	stucki	stucki	PROPN
admet-942	297	2	et	et	PROPN
admet-942	297	3	al	al	PROPN
admet-942	297	4	.	.	PROPN
admet-942	297	5	developed	develop	VERB
admet-942	297	6	a	a	DET
admet-942	297	7	system	system	NOUN
admet-942	297	8	that	that	PRON
admet-942	297	9	enables	enable	VERB
admet-942	297	10	the	the	DET
admet-942	297	11	imitation	imitation	NOUN
admet-942	297	12	of	of	ADP
admet-942	297	13	the	the	DET
admet-942	297	14	alveolar	alveolar	ADJ
admet-942	297	15	parenchyma	parenchyma	NOUN
admet-942	297	16	and	and	CCONJ
admet-942	297	17	that	that	PRON
admet-942	297	18	can	can	AUX
admet-942	297	19	produce	produce	VERB
admet-942	297	20	a	a	DET
admet-942	297	21	mechanical	mechanical	ADJ
admet-942	297	22	stretching	stretching	NOUN
admet-942	297	23	that	that	PRON
admet-942	297	24	mimics	mimic	VERB
admet-942	297	25	the	the	DET
admet-942	297	26	breathing	breathing	NOUN
admet-942	297	27	mechanism	mechanism	NOUN
admet-942	297	28	using	use	VERB
admet-942	297	29	a	a	DET
admet-942	297	30	pneumatic	pneumatic	ADJ
admet-942	297	31	micro	micro	NOUN
admet-942	297	32	-	-	NOUN
admet-942	297	33	diaphragm	diaphragm	PROPN
admet-942	297	34	.	.	PUNCT
admet-942	298	1	they	they	PRON
admet-942	298	2	demonstrated	demonstrate	VERB
admet-942	298	3	that	that	SCONJ
admet-942	298	4	the	the	DET
admet-942	298	5	mechanical	mechanical	ADJ
admet-942	298	6	stress	stress	NOUN
admet-942	298	7	affects	affect	VERB
admet-942	298	8	the	the	DET
admet-942	298	9	epithelial	epithelial	ADJ
admet-942	298	10	barrier	barrier	NOUN
admet-942	298	11	permeability	permeability	NOUN
admet-942	299	1	[	[	X
admet-942	299	2	99	99	NUM
admet-942	299	3	]	]	PUNCT
admet-942	299	4	,	,	PUNCT
admet-942	299	5	which	which	PRON
admet-942	299	6	i	i	PROPN
admet-942	299	7	d	d	VERB
admet-942	299	8	something	something	PRON
admet-942	299	9	to	to	PART
admet-942	299	10	consider	consider	VERB
admet-942	299	11	when	when	SCONJ
admet-942	299	12	manufacturing	manufacture	VERB
admet-942	299	13	other	other	ADJ
admet-942	299	14	lung	lung	NOUN
admet-942	299	15	models	model	NOUN
admet-942	299	16	reproducing	reproduce	VERB
admet-942	299	17	somehow	somehow	ADV
admet-942	299	18	this	this	DET
admet-942	299	19	kind	kind	NOUN
admet-942	299	20	of	of	ADP
admet-942	299	21	mechanical	mechanical	ADJ
admet-942	299	22	stress	stress	NOUN
admet-942	299	23	.	.	PUNCT
admet-942	300	1	felder	felder	NOUN
admet-942	300	2	et	et	PROPN
admet-942	300	3	al	al	PROPN
admet-942	300	4	.	.	PROPN
admet-942	300	5	studied	study	VERB
admet-942	300	6	wound	wound	NOUN
admet-942	300	7	healing	healing	NOUN
admet-942	300	8	recreating	recreate	VERB
admet-942	300	9	an	an	DET
admet-942	300	10	alveolar	alveolar	ADJ
admet-942	300	11	epithelium	epithelium	NOUN
admet-942	300	12	on	on	ADP
admet-942	300	13	a	a	DET
admet-942	300	14	chip	chip	NOUN
admet-942	300	15	also	also	ADV
admet-942	300	16	including	include	VERB
admet-942	300	17	mechanical	mechanical	ADJ
admet-942	300	18	strain	strain	NOUN
admet-942	300	19	with	with	ADP
admet-942	300	20	the	the	DET
admet-942	300	21	incorporation	incorporation	NOUN
admet-942	300	22	of	of	ADP
admet-942	300	23	an	an	DET
admet-942	300	24	ultra	ultra	ADJ
admet-942	300	25	-	-	ADJ
admet-942	300	26	thin	thin	ADJ
admet-942	300	27	elastic	elastic	ADJ
admet-942	300	28	membrane	membrane	NOUN
admet-942	300	29	(	(	PUNCT
admet-942	300	30	figure	figure	NOUN
admet-942	300	31	6	6	NUM
admet-942	300	32	)	)	PUNCT
admet-942	300	33	.	.	PUNCT
admet-942	301	1	this	this	DET
admet-942	301	2	device	device	NOUN
admet-942	301	3	used	use	VERB
admet-942	301	4	immunofluorescence	immunofluorescence	NOUN
admet-942	301	5	microscopy	microscopy	NOUN
admet-942	301	6	and	and	CCONJ
admet-942	301	7	scanning	scan	VERB
admet-942	301	8	electron	electron	NOUN
admet-942	301	9	microscopy	microscopy	NOUN
admet-942	301	10	for	for	ADP
admet-942	301	11	the	the	DET
admet-942	301	12	evaluation	evaluation	NOUN
admet-942	301	13	of	of	ADP
admet-942	301	14	test	test	NOUN
admet-942	301	15	outcomes	outcome	NOUN
admet-942	301	16	[	[	X
admet-942	301	17	100	100	NUM
admet-942	301	18	]	]	PUNCT
admet-942	301	19	.	.	PUNCT
admet-942	302	1	the	the	DET
admet-942	302	2	lung	lung	NOUN
admet-942	302	3	-	-	PUNCT
admet-942	302	4	on	on	ADP
admet-942	302	5	-	-	PUNCT
admet-942	302	6	a	a	DET
admet-942	302	7	-	-	PUNCT
admet-942	302	8	chip	chip	NOUN
admet-942	302	9	developed	develop	VERB
admet-942	302	10	by	by	ADP
admet-942	302	11	asad	asad	PROPN
admet-942	302	12	et	et	PROPN
admet-942	302	13	al	al	PROPN
admet-942	302	14	.	.	PROPN
admet-942	302	15	incorporated	incorporate	VERB
admet-942	302	16	on	on	ADP
admet-942	302	17	line	line	NOUN
admet-942	302	18	detection	detection	NOUN
admet-942	302	19	of	of	ADP
admet-942	302	20	ph	ph	NOUN
admet-942	302	21	and	and	CCONJ
admet-942	302	22	trans	trans	ADJ
admet-942	302	23	-	-	ADJ
admet-942	302	24	epithelial	epithelial	ADJ
admet-942	302	25	electrical	electrical	ADJ
admet-942	302	26	impedance	impedance	NOUN
admet-942	302	27	,	,	PUNCT
admet-942	302	28	as	as	ADV
admet-942	302	29	well	well	ADV
admet-942	302	30	as	as	ADP
admet-942	302	31	a	a	DET
admet-942	302	32	microscope	microscope	NOUN
admet-942	302	33	that	that	PRON
admet-942	302	34	allows	allow	VERB
admet-942	302	35	visual	visual	ADJ
admet-942	302	36	monitoring	monitoring	NOUN
admet-942	302	37	due	due	ADP
admet-942	302	38	to	to	ADP
admet-942	302	39	the	the	DET
admet-942	302	40	chip	chip	NOUN
admet-942	302	41	’s	’s	PART
admet-942	302	42	transparency	transparency	NOUN
admet-942	303	1	[	[	X
admet-942	303	2	101	101	NUM
admet-942	303	3	]	]	PUNCT
admet-942	303	4	.	.	PUNCT
admet-942	304	1	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	304	2	r.	r.	PROPN
admet-942	304	3	vargas	vargas	PROPN
admet-942	304	4	,	,	PUNCT
admet-942	304	5	a.	a.	NOUN
admet-942	304	6	egurbide	egurbide	NOUN
admet-942	304	7	-	-	PUNCT
admet-942	304	8	sifre	sifre	NOUN
admet-942	304	9	and	and	CCONJ
admet-942	304	10	l.	l.	PROPN
admet-942	304	11	medina	medina	PROPN
admet-942	304	12	admet	admet	PROPN
admet-942	304	13	&	&	CCONJ
admet-942	304	14	dmpk	dmpk	PROPN
admet-942	304	15	9(2	9(2	NUM
admet-942	304	16	)	)	PUNCT
admet-942	304	17	(	(	PUNCT
admet-942	304	18	2021	2021	NUM
admet-942	304	19	)	)	PUNCT
admet-942	304	20	111	111	NUM
admet-942	304	21	-	-	SYM
admet-942	304	22	141	141	NUM
admet-942	304	23	122	122	NUM
admet-942	304	24	figure	figure	NOUN
admet-942	304	25	5	5	NUM
admet-942	304	26	.	.	PUNCT
admet-942	304	27	kidney	kidney	NOUN
admet-942	304	28	-	-	PUNCT
admet-942	304	29	on	on	ADP
admet-942	304	30	-	-	PUNCT
admet-942	304	31	a	a	DET
admet-942	304	32	-	-	PUNCT
admet-942	304	33	chip	chip	NOUN
admet-942	304	34	device	device	NOUN
admet-942	304	35	for	for	ADP
admet-942	304	36	drug	drug	NOUN
admet-942	304	37	screening	screening	NOUN
admet-942	304	38	and	and	CCONJ
admet-942	304	39	nephrotoxicity	nephrotoxicity	NOUN
admet-942	304	40	assessment	assessment	NOUN
admet-942	304	41	.	.	PUNCT
admet-942	305	1	a	a	DET
admet-942	305	2	)	)	PUNCT
admet-942	305	3	schematic	schematic	ADJ
admet-942	305	4	representation	representation	NOUN
admet-942	305	5	of	of	ADP
admet-942	305	6	the	the	DET
admet-942	305	7	chip	chip	NOUN
admet-942	305	8	’s	’s	PART
admet-942	305	9	two	two	NUM
admet-942	305	10	chambers	chamber	NOUN
admet-942	305	11	.	.	PUNCT
admet-942	306	1	b	b	X
admet-942	306	2	)	)	PUNCT
admet-942	306	3	diagram	diagram	NOUN
admet-942	306	4	of	of	ADP
admet-942	306	5	the	the	DET
admet-942	306	6	complete	complete	ADJ
admet-942	306	7	device	device	NOUN
admet-942	306	8	including	include	VERB
admet-942	306	9	:	:	PUNCT
admet-942	306	10	the	the	DET
admet-942	306	11	chip	chip	NOUN
admet-942	306	12	and	and	CCONJ
admet-942	306	13	the	the	DET
admet-942	306	14	temperature	temperature	NOUN
admet-942	306	15	and	and	CCONJ
admet-942	306	16	the	the	DET
admet-942	306	17	flow	flow	NOUN
admet-942	306	18	control	control	NOUN
admet-942	306	19	device	device	NOUN
admet-942	306	20	.	.	PUNCT
admet-942	307	1	adapted	adapt	VERB
admet-942	307	2	from	from	ADP
admet-942	307	3	[	[	X
admet-942	307	4	97	97	NUM
admet-942	307	5	]	]	PUNCT
admet-942	307	6	under	under	ADP
admet-942	307	7	terms	term	NOUN
admet-942	307	8	of	of	ADP
admet-942	307	9	the	the	DET
admet-942	307	10	creative	creative	ADJ
admet-942	307	11	commons	common	NOUN
admet-942	307	12	attribution	attribution	NOUN
admet-942	307	13	license	license	NOUN
admet-942	307	14	.	.	PUNCT
admet-942	308	1	copyright	copyright	NOUN
admet-942	308	2	(	(	PUNCT
admet-942	308	3	2020	2020	NUM
admet-942	308	4	)	)	PUNCT
admet-942	308	5	.	.	PUNCT
admet-942	309	1	gut	gut	VERB
admet-942	309	2	-	-	PUNCT
admet-942	309	3	on	on	ADP
admet-942	309	4	-	-	PUNCT
admet-942	309	5	a	a	DET
admet-942	309	6	-	-	PUNCT
admet-942	309	7	chip	chip	NOUN
admet-942	309	8	the	the	DET
admet-942	309	9	small	small	ADJ
admet-942	309	10	intestine	intestine	NOUN
admet-942	309	11	has	have	VERB
admet-942	309	12	important	important	ADJ
admet-942	309	13	functions	function	NOUN
admet-942	309	14	associated	associate	VERB
admet-942	309	15	with	with	ADP
admet-942	309	16	drug	drug	NOUN
admet-942	309	17	absorption	absorption	NOUN
admet-942	309	18	and	and	CCONJ
admet-942	309	19	the	the	DET
admet-942	309	20	immune	immune	ADJ
admet-942	309	21	system	system	NOUN
admet-942	309	22	[	[	X
admet-942	309	23	2,7	2,7	NUM
admet-942	309	24	]	]	PUNCT
admet-942	309	25	.	.	PUNCT
admet-942	310	1	applications	application	NOUN
admet-942	310	2	for	for	ADP
admet-942	310	3	ooc	ooc	ADJ
admet-942	310	4	-	-	PUNCT
admet-942	310	5	gut	gut	NOUN
admet-942	310	6	models	model	NOUN
admet-942	310	7	include	include	VERB
admet-942	310	8	pharmacodynamics	pharmacodynamic	NOUN
admet-942	310	9	,	,	PUNCT
admet-942	310	10	pharmacokinetics	pharmacokinetic	NOUN
admet-942	310	11	and	and	CCONJ
admet-942	310	12	physiological	physiological	ADJ
admet-942	310	13	studies	study	NOUN
admet-942	310	14	,	,	PUNCT
admet-942	310	15	and	and	CCONJ
admet-942	310	16	are	be	AUX
admet-942	310	17	frequently	frequently	ADV
admet-942	310	18	linked	link	VERB
admet-942	310	19	with	with	ADP
admet-942	310	20	the	the	DET
admet-942	310	21	use	use	NOUN
admet-942	310	22	of	of	ADP
admet-942	310	23	caco2	caco2	NOUN
admet-942	310	24	cells	cell	NOUN
admet-942	310	25	.	.	PUNCT
admet-942	311	1	these	these	DET
admet-942	311	2	gut	gut	NOUN
admet-942	311	3	-	-	PUNCT
admet-942	311	4	on	on	ADP
admet-942	311	5	-	-	PUNCT
admet-942	311	6	a	a	DET
admet-942	311	7	-	-	PUNCT
admet-942	311	8	chip	chip	NOUN
admet-942	311	9	models	model	NOUN
admet-942	311	10	enable	enable	VERB
admet-942	311	11	to	to	PART
admet-942	311	12	investigate	investigate	VERB
admet-942	311	13	the	the	DET
admet-942	311	14	way	way	NOUN
admet-942	311	15	how	how	SCONJ
admet-942	311	16	the	the	DET
admet-942	311	17	tissue	tissue	NOUN
admet-942	311	18	-	-	PUNCT
admet-942	311	19	microbiota	microbiota	NOUN
admet-942	311	20	interrelationship	interrelationship	NOUN
admet-942	311	21	can	can	AUX
admet-942	311	22	affect	affect	VERB
admet-942	311	23	the	the	DET
admet-942	311	24	nutrient	nutrient	ADJ
admet-942	311	25	absorption	absorption	NOUN
admet-942	311	26	in	in	ADP
admet-942	311	27	the	the	DET
admet-942	311	28	gut	gut	NOUN
admet-942	311	29	,	,	PUNCT
admet-942	311	30	and	and	CCONJ
admet-942	311	31	allow	allow	VERB
admet-942	311	32	the	the	DET
admet-942	311	33	study	study	NOUN
admet-942	311	34	of	of	ADP
admet-942	311	35	the	the	DET
admet-942	311	36	signaling	signaling	NOUN
admet-942	311	37	between	between	ADP
admet-942	311	38	gastric	gastric	ADJ
admet-942	311	39	and	and	CCONJ
admet-942	311	40	intestinal	intestinal	ADJ
admet-942	311	41	cells	cell	NOUN
admet-942	311	42	[	[	X
admet-942	311	43	1,54,72,103	1,54,72,103	NUM
admet-942	311	44	]	]	X
admet-942	311	45	.	.	PUNCT
admet-942	312	1	ooc	ooc	ADJ
admet-942	312	2	-	-	PUNCT
admet-942	312	3	gut	gut	NOUN
admet-942	312	4	models	model	NOUN
admet-942	312	5	have	have	AUX
admet-942	312	6	also	also	ADV
admet-942	312	7	been	be	AUX
admet-942	312	8	used	use	VERB
admet-942	312	9	to	to	PART
admet-942	312	10	evaluate	evaluate	VERB
admet-942	312	11	the	the	DET
admet-942	312	12	mucus	mucus	NOUN
admet-942	312	13	formation	formation	NOUN
admet-942	312	14	,	,	PUNCT
admet-942	312	15	accumulation	accumulation	NOUN
admet-942	312	16	and	and	CCONJ
admet-942	312	17	impact	impact	NOUN
admet-942	312	18	on	on	ADP
admet-942	312	19	intestinal	intestinal	ADJ
admet-942	312	20	functionality	functionality	NOUN
admet-942	313	1	[	[	X
admet-942	313	2	31,72	31,72	NOUN
admet-942	313	3	]	]	X
admet-942	313	4	.	.	PUNCT
admet-942	314	1	peters	peters	PROPN
admet-942	314	2	et	et	PROPN
admet-942	314	3	al	al	PROPN
admet-942	314	4	.	.	PROPN
admet-942	314	5	highlighted	highlight	VERB
admet-942	314	6	the	the	DET
admet-942	314	7	importance	importance	NOUN
admet-942	314	8	of	of	ADP
admet-942	314	9	in	in	ADP
admet-942	314	10	vitro	vitro	X
admet-942	314	11	testing	testing	NOUN
admet-942	314	12	to	to	PART
admet-942	314	13	assess	assess	VERB
admet-942	314	14	gastrointestinal	gastrointestinal	ADJ
admet-942	314	15	safety	safety	NOUN
admet-942	314	16	[	[	X
admet-942	314	17	54	54	NUM
admet-942	314	18	]	]	PUNCT
admet-942	314	19	.	.	PUNCT
admet-942	315	1	in	in	ADP
admet-942	315	2	another	another	DET
admet-942	315	3	approach	approach	NOUN
admet-942	315	4	,	,	PUNCT
admet-942	315	5	de	de	X
admet-942	315	6	haan	haan	PROPN
admet-942	315	7	et	et	PROPN
admet-942	315	8	al	al	PROPN
admet-942	315	9	.	.	PROPN
admet-942	315	10	monitored	monitor	VERB
admet-942	315	11	enzymatic	enzymatic	ADJ
admet-942	315	12	digestion	digestion	NOUN
admet-942	315	13	of	of	ADP
admet-942	315	14	milk	milk	NOUN
admet-942	315	15	using	use	VERB
admet-942	315	16	a	a	DET
admet-942	315	17	microfluidic	microfluidic	ADJ
admet-942	315	18	chip	chip	NOUN
admet-942	315	19	and	and	CCONJ
admet-942	315	20	demonstrated	demonstrate	VERB
admet-942	315	21	the	the	DET
admet-942	315	22	importance	importance	NOUN
admet-942	315	23	of	of	ADP
admet-942	315	24	adjusting	adjust	VERB
admet-942	315	25	and	and	CCONJ
admet-942	315	26	correlating	correlate	VERB
admet-942	315	27	digestion	digestion	NOUN
admet-942	315	28	times	time	NOUN
admet-942	315	29	at	at	ADP
admet-942	315	30	physiological	physiological	ADJ
admet-942	315	31	conditions	condition	NOUN
admet-942	315	32	on	on	ADP
admet-942	315	33	ooc	ooc	PRON
admet-942	315	34	[	[	X
admet-942	315	35	69	69	NUM
admet-942	315	36	]	]	SYM
admet-942	315	37	.	.	PUNCT
admet-942	316	1	sailer	sailer	PROPN
admet-942	316	2	et	et	PROPN
admet-942	316	3	al	al	PROPN
admet-942	316	4	.	.	PROPN
admet-942	316	5	built	build	VERB
admet-942	316	6	a	a	DET
admet-942	316	7	gut	gut	NOUN
admet-942	316	8	-	-	PUNCT
admet-942	316	9	on	on	ADP
admet-942	316	10	-	-	PUNCT
admet-942	316	11	a	a	DET
admet-942	316	12	-	-	PUNCT
admet-942	316	13	chip	chip	NOUN
admet-942	316	14	from	from	ADP
admet-942	316	15	patient	patient	NOUN
admet-942	316	16	-	-	PUNCT
admet-942	316	17	derived	derive	VERB
admet-942	316	18	intestinal	intestinal	ADJ
admet-942	316	19	subepithelial	subepithelial	ADJ
admet-942	316	20	myofibroblasts	myofibroblast	NOUN
admet-942	316	21	,	,	PUNCT
admet-942	316	22	which	which	PRON
admet-942	316	23	incorporated	incorporate	VERB
admet-942	316	24	growth	growth	NOUN
admet-942	316	25	factors	factor	NOUN
admet-942	316	26	and	and	CCONJ
admet-942	316	27	controlled	control	VERB
admet-942	316	28	physiological	physiological	ADJ
admet-942	316	29	conditions	condition	NOUN
admet-942	316	30	that	that	PRON
admet-942	316	31	showed	show	VERB
admet-942	316	32	angiogenic	angiogenic	ADJ
admet-942	316	33	properties	property	NOUN
admet-942	316	34	under	under	ADP
admet-942	316	35	simulated	simulated	ADJ
admet-942	316	36	perfusion	perfusion	NOUN
admet-942	316	37	(	(	PUNCT
admet-942	316	38	figure	figure	NOUN
admet-942	316	39	7	7	NUM
admet-942	316	40	)	)	PUNCT
admet-942	317	1	[	[	X
admet-942	317	2	105	105	NUM
admet-942	317	3	]	]	PUNCT
admet-942	317	4	.	.	PUNCT
admet-942	318	1	the	the	PRON
admet-942	318	2	gut	gut	NOUN
admet-942	318	3	-	-	PUNCT
admet-942	318	4	on	on	ADP
admet-942	318	5	-	-	PUNCT
admet-942	318	6	a	a	DET
admet-942	318	7	-	-	PUNCT
admet-942	318	8	chip	chip	NOUN
admet-942	318	9	also	also	ADV
admet-942	318	10	can	can	AUX
admet-942	318	11	be	be	AUX
admet-942	318	12	found	find	VERB
admet-942	318	13	coupled	couple	VERB
admet-942	318	14	with	with	ADP
admet-942	318	15	other	other	ADJ
admet-942	318	16	organs	organ	NOUN
admet-942	318	17	,	,	PUNCT
admet-942	318	18	such	such	ADJ
admet-942	318	19	as	as	ADP
admet-942	318	20	the	the	DET
admet-942	318	21	liver	liver	NOUN
admet-942	318	22	,	,	PUNCT
admet-942	318	23	which	which	PRON
admet-942	318	24	allows	allow	VERB
admet-942	318	25	to	to	PART
admet-942	318	26	study	study	VERB
admet-942	318	27	the	the	DET
admet-942	318	28	absorption	absorption	NOUN
admet-942	318	29	and	and	CCONJ
admet-942	318	30	metabolism	metabolism	NOUN
admet-942	318	31	of	of	ADP
admet-942	318	32	drugs	drug	NOUN
admet-942	318	33	[	[	X
admet-942	318	34	51	51	NUM
admet-942	318	35	]	]	PUNCT
admet-942	318	36	.	.	PUNCT
admet-942	319	1	admet	admet	PROPN
admet-942	319	2	&	&	CCONJ
admet-942	319	3	dmpk	dmpk	PROPN
admet-942	319	4	9(2	9(2	NUM
admet-942	319	5	)	)	PUNCT
admet-942	319	6	(	(	PUNCT
admet-942	319	7	2021	2021	NUM
admet-942	319	8	)	)	PUNCT
admet-942	319	9	111	111	NUM
admet-942	319	10	-	-	SYM
admet-942	319	11	141	141	NUM
admet-942	319	12	organ	organ	NOUN
admet-942	319	13	-	-	PUNCT
admet-942	319	14	on	on	ADP
admet-942	319	15	-	-	PUNCT
admet-942	319	16	a	a	DET
admet-942	319	17	-	-	PUNCT
admet-942	319	18	chip	chip	NOUN
admet-942	319	19	systems	system	NOUN
admet-942	319	20	for	for	ADP
admet-942	319	21	new	new	ADJ
admet-942	319	22	drugs	drug	NOUN
admet-942	319	23	development	development	NOUN
admet-942	319	24	doi	doi	PROPN
admet-942	319	25	:	:	PUNCT
admet-942	319	26	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	319	27	123	123	NUM
admet-942	319	28	figure	figure	NOUN
admet-942	319	29	6	6	NUM
admet-942	319	30	.	.	PUNCT
admet-942	319	31	mimicking	mimic	VERB
admet-942	319	32	of	of	ADP
admet-942	319	33	breathing	breathing	NOUN
admet-942	319	34	mechanics	mechanic	NOUN
admet-942	319	35	.	.	PUNCT
admet-942	320	1	schematic	schematic	ADJ
admet-942	320	2	representation	representation	NOUN
admet-942	320	3	of	of	ADP
admet-942	320	4	a	a	PRON
admet-942	320	5	)	)	PUNCT
admet-942	320	6	the	the	DET
admet-942	320	7	movement	movement	NOUN
admet-942	320	8	of	of	ADP
admet-942	320	9	the	the	DET
admet-942	320	10	diaphragm	diaphragm	NOUN
admet-942	320	11	leading	lead	VERB
admet-942	320	12	to	to	ADP
admet-942	320	13	the	the	DET
admet-942	320	14	lungs	lung	NOUN
admet-942	320	15	expansion	expansion	NOUN
admet-942	320	16	during	during	ADP
admet-942	320	17	inhalation	inhalation	NOUN
admet-942	320	18	and	and	CCONJ
admet-942	320	19	b	b	NOUN
admet-942	320	20	)	)	PUNCT
admet-942	320	21	the	the	DET
admet-942	320	22	imitation	imitation	NOUN
admet-942	320	23	of	of	ADP
admet-942	320	24	this	this	DET
admet-942	320	25	motion	motion	NOUN
admet-942	320	26	by	by	ADP
admet-942	320	27	a	a	DET
admet-942	320	28	mechanical	mechanical	ADJ
admet-942	320	29	microdiaphragm	microdiaphragm	NOUN
admet-942	320	30	used	use	VERB
admet-942	320	31	in	in	ADP
admet-942	320	32	lung	lung	NOUN
admet-942	320	33	-	-	PUNCT
admet-942	320	34	on	on	ADP
admet-942	320	35	-	-	PUNCT
admet-942	320	36	a	a	DET
admet-942	320	37	-	-	PUNCT
admet-942	320	38	chip	chip	NOUN
admet-942	320	39	devices	device	NOUN
admet-942	320	40	.	.	PUNCT
admet-942	321	1	reproduced	reproduce	VERB
admet-942	321	2	from	from	ADP
admet-942	321	3	[	[	X
admet-942	321	4	100	100	NUM
admet-942	321	5	]	]	PUNCT
admet-942	321	6	under	under	ADP
admet-942	321	7	terms	term	NOUN
admet-942	321	8	of	of	ADP
admet-942	321	9	the	the	DET
admet-942	321	10	creative	creative	ADJ
admet-942	321	11	commons	common	NOUN
admet-942	321	12	attribution	attribution	NOUN
admet-942	321	13	license	license	NOUN
admet-942	321	14	.	.	PUNCT
admet-942	322	1	copyright	copyright	NOUN
admet-942	322	2	(	(	PUNCT
admet-942	322	3	2019	2019	NUM
admet-942	322	4	)	)	PUNCT
admet-942	322	5	figure	figure	NOUN
admet-942	322	6	7	7	NUM
admet-942	322	7	.	.	PUNCT
admet-942	323	1	gut	gut	VERB
admet-942	323	2	-	-	PUNCT
admet-942	323	3	on	on	ADP
admet-942	323	4	-	-	PUNCT
admet-942	323	5	a	a	DET
admet-942	323	6	-	-	PUNCT
admet-942	323	7	chip	chip	NOUN
admet-942	323	8	(	(	PUNCT
admet-942	323	9	goc	goc	PROPN
admet-942	323	10	)	)	PUNCT
admet-942	323	11	formed	form	VERB
admet-942	323	12	by	by	ADP
admet-942	323	13	two	two	NUM
admet-942	323	14	channels	channel	NOUN
admet-942	323	15	separated	separate	VERB
admet-942	323	16	by	by	ADP
admet-942	323	17	a	a	DET
admet-942	323	18	thin	thin	ADJ
admet-942	323	19	membrane	membrane	NOUN
admet-942	323	20	with	with	ADP
admet-942	323	21	perfusion	perfusion	NOUN
admet-942	323	22	vasculature	vasculature	NOUN
admet-942	323	23	on	on	ADP
admet-942	323	24	the	the	DET
admet-942	323	25	lower	low	ADJ
admet-942	323	26	channel	channel	NOUN
admet-942	323	27	.	.	PUNCT
admet-942	324	1	adapted	adapt	VERB
admet-942	324	2	from	from	ADP
admet-942	324	3	[	[	X
admet-942	324	4	105	105	NUM
admet-942	324	5	]	]	PUNCT
admet-942	324	6	under	under	ADP
admet-942	324	7	terms	term	NOUN
admet-942	324	8	of	of	ADP
admet-942	324	9	the	the	DET
admet-942	324	10	creative	creative	ADJ
admet-942	324	11	commons	common	NOUN
admet-942	324	12	attribution	attribution	NOUN
admet-942	324	13	license	license	NOUN
admet-942	324	14	.	.	PUNCT
admet-942	325	1	copyright	copyright	NOUN
admet-942	325	2	(	(	PUNCT
admet-942	325	3	2020	2020	NUM
admet-942	325	4	)	)	PUNCT
admet-942	325	5	.	.	PUNCT
admet-942	326	1	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	326	2	r.	r.	PROPN
admet-942	326	3	vargas	vargas	PROPN
admet-942	326	4	,	,	PUNCT
admet-942	326	5	a.	a.	NOUN
admet-942	326	6	egurbide	egurbide	NOUN
admet-942	326	7	-	-	PUNCT
admet-942	326	8	sifre	sifre	NOUN
admet-942	326	9	and	and	CCONJ
admet-942	326	10	l.	l.	PROPN
admet-942	326	11	medina	medina	PROPN
admet-942	326	12	admet	admet	PROPN
admet-942	326	13	&	&	CCONJ
admet-942	326	14	dmpk	dmpk	PROPN
admet-942	326	15	9(2	9(2	NUM
admet-942	326	16	)	)	PUNCT
admet-942	326	17	(	(	PUNCT
admet-942	326	18	2021	2021	NUM
admet-942	326	19	)	)	PUNCT
admet-942	326	20	111	111	NUM
admet-942	326	21	-	-	SYM
admet-942	326	22	141	141	NUM
admet-942	326	23	124	124	NUM
admet-942	326	24	liver	liver	NOUN
admet-942	326	25	-	-	PUNCT
admet-942	326	26	on	on	ADP
admet-942	326	27	-	-	PUNCT
admet-942	326	28	a	a	DET
admet-942	326	29	-	-	PUNCT
admet-942	326	30	chip	chip	NOUN
admet-942	326	31	the	the	DET
admet-942	326	32	liver	liver	NOUN
admet-942	326	33	plays	play	VERB
admet-942	326	34	a	a	DET
admet-942	326	35	crucial	crucial	ADJ
admet-942	326	36	role	role	NOUN
admet-942	326	37	in	in	ADP
admet-942	326	38	the	the	DET
admet-942	326	39	drug	drug	NOUN
admet-942	326	40	metabolism	metabolism	NOUN
admet-942	326	41	and	and	CCONJ
admet-942	326	42	the	the	DET
admet-942	326	43	detoxification	detoxification	NOUN
admet-942	326	44	of	of	ADP
admet-942	326	45	the	the	DET
admet-942	326	46	body	body	NOUN
admet-942	326	47	.	.	PUNCT
admet-942	327	1	therefore	therefore	ADV
admet-942	327	2	,	,	PUNCT
admet-942	327	3	it	it	PRON
admet-942	327	4	is	be	AUX
admet-942	327	5	another	another	DET
admet-942	327	6	important	important	ADJ
admet-942	327	7	organ	organ	NOUN
admet-942	327	8	to	to	PART
admet-942	327	9	take	take	VERB
admet-942	327	10	into	into	ADP
admet-942	327	11	consideration	consideration	NOUN
admet-942	327	12	during	during	ADP
admet-942	327	13	the	the	DET
admet-942	327	14	development	development	NOUN
admet-942	327	15	of	of	ADP
admet-942	327	16	new	new	ADJ
admet-942	327	17	drugs	drug	NOUN
admet-942	327	18	and	and	CCONJ
admet-942	327	19	their	their	PRON
admet-942	327	20	effects	effect	NOUN
admet-942	327	21	in	in	ADP
admet-942	327	22	the	the	DET
admet-942	327	23	other	other	ADJ
admet-942	327	24	parts	part	NOUN
admet-942	327	25	of	of	ADP
admet-942	327	26	the	the	DET
admet-942	327	27	system	system	NOUN
admet-942	327	28	[	[	X
admet-942	327	29	2,11,21,89	2,11,21,89	NUM
admet-942	327	30	]	]	X
admet-942	327	31	.	.	PUNCT
admet-942	328	1	liver	liver	NOUN
admet-942	328	2	cells	cell	NOUN
admet-942	328	3	grown	grow	VERB
admet-942	328	4	under	under	ADP
admet-942	328	5	3d	3d	PROPN
admet-942	328	6	conditions	condition	NOUN
admet-942	328	7	are	be	AUX
admet-942	328	8	more	more	ADV
admet-942	328	9	viable	viable	ADJ
admet-942	328	10	,	,	PUNCT
admet-942	328	11	functional	functional	ADJ
admet-942	328	12	and	and	CCONJ
admet-942	328	13	reproducible	reproducible	ADJ
admet-942	328	14	than	than	ADP
admet-942	328	15	those	those	PRON
admet-942	328	16	cultured	cultured	ADJ
admet-942	328	17	in	in	ADP
admet-942	328	18	2d	2d	NUM
admet-942	328	19	[	[	X
admet-942	328	20	2,108	2,108	NUM
admet-942	328	21	]	]	PUNCT
admet-942	328	22	.	.	PUNCT
admet-942	329	1	liver	liver	NOUN
admet-942	329	2	-	-	PUNCT
admet-942	329	3	on	on	ADP
admet-942	329	4	-	-	PUNCT
admet-942	329	5	a	a	DET
admet-942	329	6	-	-	PUNCT
admet-942	329	7	chip	chip	NOUN
admet-942	329	8	models	model	NOUN
admet-942	329	9	associated	associate	VERB
admet-942	329	10	with	with	ADP
admet-942	329	11	other	other	ADJ
admet-942	329	12	tissues	tissue	NOUN
admet-942	329	13	or	or	CCONJ
admet-942	329	14	organs	organ	NOUN
admet-942	329	15	,	,	PUNCT
admet-942	329	16	such	such	ADJ
admet-942	329	17	as	as	ADP
admet-942	329	18	the	the	DET
admet-942	329	19	intestine	intestine	NOUN
admet-942	329	20	,	,	PUNCT
admet-942	329	21	may	may	AUX
admet-942	329	22	allow	allow	VERB
admet-942	329	23	to	to	PART
admet-942	329	24	obtain	obtain	VERB
admet-942	329	25	first	first	ADJ
admet-942	329	26	-	-	PUNCT
admet-942	329	27	step	step	NOUN
admet-942	329	28	metabolism	metabolism	NOUN
admet-942	329	29	profiles	profile	NOUN
admet-942	329	30	closer	close	ADJ
admet-942	329	31	to	to	ADP
admet-942	329	32	those	those	PRON
admet-942	329	33	that	that	PRON
admet-942	329	34	could	could	AUX
admet-942	329	35	be	be	AUX
admet-942	329	36	acquired	acquire	VERB
admet-942	329	37	through	through	ADP
admet-942	329	38	traditional	traditional	ADJ
admet-942	329	39	cell	cell	NOUN
admet-942	329	40	cultures	culture	NOUN
admet-942	329	41	[	[	X
admet-942	329	42	1,3,89	1,3,89	NUM
admet-942	329	43	]	]	PUNCT
admet-942	329	44	.	.	PUNCT
admet-942	330	1	jia	jia	PROPN
admet-942	330	2	et	et	PROPN
admet-942	330	3	al	al	PROPN
admet-942	330	4	.	.	PROPN
admet-942	330	5	described	describe	VERB
admet-942	330	6	a	a	DET
admet-942	330	7	3d	3d	NUM
admet-942	330	8	hepatic	hepatic	NOUN
admet-942	330	9	system	system	NOUN
admet-942	330	10	for	for	ADP
admet-942	330	11	liver	liver	NOUN
admet-942	330	12	injury	injury	NOUN
admet-942	330	13	studies	study	NOUN
admet-942	330	14	by	by	ADP
admet-942	330	15	controlling	control	VERB
admet-942	330	16	hepatocyte	hepatocyte	NOUN
admet-942	330	17	viability	viability	NOUN
admet-942	330	18	,	,	PUNCT
admet-942	330	19	function	function	NOUN
admet-942	330	20	,	,	PUNCT
admet-942	330	21	morphology	morphology	NOUN
admet-942	330	22	and	and	CCONJ
admet-942	330	23	polarity	polarity	NOUN
admet-942	330	24	,	,	PUNCT
admet-942	330	25	and	and	CCONJ
admet-942	330	26	thus	thus	ADV
admet-942	330	27	,	,	PUNCT
admet-942	330	28	maintaining	maintain	VERB
admet-942	330	29	the	the	DET
admet-942	330	30	tissue	tissue	NOUN
admet-942	330	31	morphology	morphology	NOUN
admet-942	330	32	,	,	PUNCT
admet-942	330	33	mrna	mrna	PROPN
admet-942	330	34	expression	expression	NOUN
admet-942	330	35	,	,	PUNCT
admet-942	330	36	bile	bile	NOUN
admet-942	330	37	secretion	secretion	NOUN
admet-942	330	38	and	and	CCONJ
admet-942	330	39	a	a	DET
admet-942	330	40	better	well	ADJ
admet-942	330	41	cell	cell	NOUN
admet-942	330	42	viability	viability	NOUN
admet-942	330	43	compared	compare	VERB
admet-942	330	44	to	to	ADP
admet-942	330	45	other	other	ADJ
admet-942	330	46	types	type	NOUN
admet-942	330	47	of	of	ADP
admet-942	330	48	cell	cell	NOUN
admet-942	330	49	cultures	culture	NOUN
admet-942	330	50	.	.	PUNCT
admet-942	331	1	they	they	PRON
admet-942	331	2	controlled	control	VERB
admet-942	331	3	the	the	DET
admet-942	331	4	morphology	morphology	NOUN
admet-942	331	5	encapsulating	encapsulate	VERB
admet-942	331	6	the	the	DET
admet-942	331	7	cell	cell	NOUN
admet-942	331	8	culture	culture	NOUN
admet-942	331	9	inside	inside	ADP
admet-942	331	10	a	a	DET
admet-942	331	11	alginate	alginate	NOUN
admet-942	331	12	hydrogel	hydrogel	NOUN
admet-942	331	13	(	(	PUNCT
admet-942	331	14	figure	figure	NOUN
admet-942	331	15	8a	8a	NUM
admet-942	331	16	)	)	PUNCT
admet-942	332	1	[	[	X
admet-942	332	2	43	43	NUM
admet-942	332	3	]	]	PUNCT
admet-942	332	4	.	.	PUNCT
admet-942	333	1	freyer	freyer	PROPN
admet-942	333	2	et	et	PROPN
admet-942	333	3	al	al	PROPN
admet-942	333	4	.	.	PROPN
admet-942	333	5	built	build	VERB
admet-942	333	6	an	an	DET
admet-942	333	7	ooc	ooc	NOUN
admet-942	333	8	model	model	NOUN
admet-942	333	9	for	for	ADP
admet-942	333	10	hepatotoxicity	hepatotoxicity	NOUN
admet-942	333	11	testing	testing	NOUN
admet-942	333	12	,	,	PUNCT
admet-942	333	13	highlighting	highlight	VERB
admet-942	333	14	the	the	DET
admet-942	333	15	importance	importance	NOUN
admet-942	333	16	of	of	ADP
admet-942	333	17	the	the	DET
admet-942	333	18	control	control	NOUN
admet-942	333	19	and	and	CCONJ
admet-942	333	20	monitoring	monitoring	NOUN
admet-942	333	21	of	of	ADP
admet-942	333	22	chemical	chemical	ADJ
admet-942	333	23	physiological	physiological	ADJ
admet-942	333	24	parameters	parameter	NOUN
admet-942	333	25	(	(	PUNCT
admet-942	333	26	such	such	ADJ
admet-942	333	27	as	as	ADP
admet-942	333	28	lactate	lactate	NOUN
admet-942	333	29	production	production	NOUN
admet-942	333	30	and	and	CCONJ
admet-942	333	31	ammonia	ammonia	NOUN
admet-942	333	32	release	release	NOUN
admet-942	333	33	)	)	PUNCT
admet-942	333	34	(	(	PUNCT
admet-942	333	35	figure	figure	NOUN
admet-942	333	36	8b	8b	NUM
admet-942	333	37	)	)	PUNCT
admet-942	333	38	.	.	PUNCT
admet-942	334	1	they	they	PRON
admet-942	334	2	validated	validate	VERB
admet-942	334	3	the	the	DET
admet-942	334	4	ooc	ooc	NOUN
admet-942	334	5	by	by	ADP
admet-942	334	6	performing	perform	VERB
admet-942	334	7	a	a	DET
admet-942	334	8	paracetamol	paracetamol	NOUN
admet-942	334	9	hepatotoxicity	hepatotoxicity	NOUN
admet-942	334	10	determination	determination	NOUN
admet-942	334	11	,	,	PUNCT
admet-942	334	12	which	which	PRON
admet-942	334	13	included	include	VERB
admet-942	334	14	a	a	DET
admet-942	334	15	histological	histological	ADJ
admet-942	334	16	and	and	CCONJ
admet-942	334	17	immunohistochemical	immunohistochemical	ADJ
admet-942	334	18	evaluation	evaluation	NOUN
admet-942	334	19	of	of	ADP
admet-942	334	20	the	the	DET
admet-942	334	21	damage	damage	NOUN
admet-942	334	22	.	.	PUNCT
admet-942	335	1	they	they	PRON
admet-942	335	2	also	also	ADV
admet-942	335	3	stablished	stablishe	VERB
admet-942	335	4	the	the	DET
admet-942	335	5	need	need	NOUN
admet-942	335	6	of	of	ADP
admet-942	335	7	modifications	modification	NOUN
admet-942	335	8	of	of	ADP
admet-942	335	9	the	the	DET
admet-942	335	10	ooc	ooc	NOUN
admet-942	335	11	to	to	PART
admet-942	335	12	include	include	VERB
admet-942	335	13	non	non	ADJ
admet-942	335	14	-	-	ADJ
admet-942	335	15	parenchymal	parenchymal	ADJ
admet-942	335	16	cell	cell	NOUN
admet-942	335	17	types	type	NOUN
admet-942	335	18	at	at	ADP
admet-942	335	19	physiological	physiological	ADJ
admet-942	335	20	ratios	ratio	NOUN
admet-942	335	21	and	and	CCONJ
admet-942	335	22	the	the	DET
admet-942	335	23	creation	creation	NOUN
admet-942	335	24	of	of	ADP
admet-942	335	25	defined	define	VERB
admet-942	335	26	oxygen	oxygen	NOUN
admet-942	335	27	gradients	gradient	NOUN
admet-942	335	28	in	in	ADP
admet-942	335	29	order	order	NOUN
admet-942	335	30	to	to	PART
admet-942	335	31	increase	increase	VERB
admet-942	335	32	the	the	DET
admet-942	335	33	system	system	NOUN
admet-942	335	34	’s	’s	PART
admet-942	335	35	sensibility	sensibility	NOUN
admet-942	335	36	for	for	ADP
admet-942	335	37	further	further	ADJ
admet-942	335	38	toxicity	toxicity	NOUN
admet-942	335	39	studies	study	NOUN
admet-942	335	40	[	[	X
admet-942	335	41	107	107	NUM
admet-942	335	42	]	]	PUNCT
admet-942	335	43	.	.	PUNCT
admet-942	336	1	on	on	ADP
admet-942	336	2	another	another	DET
admet-942	336	3	approach	approach	NOUN
admet-942	336	4	,	,	PUNCT
admet-942	336	5	kostrzewski	kostrzewski	PROPN
admet-942	336	6	et	et	PROPN
admet-942	336	7	al	al	PROPN
admet-942	336	8	.	.	PROPN
admet-942	336	9	prepared	prepare	VERB
admet-942	336	10	a	a	DET
admet-942	336	11	3d	3d	NUM
admet-942	336	12	culture	culture	NOUN
admet-942	336	13	on	on	ADP
admet-942	336	14	a	a	DET
admet-942	336	15	plate	plate	NOUN
admet-942	336	16	from	from	ADP
admet-942	336	17	primary	primary	ADJ
admet-942	336	18	cells	cell	NOUN
admet-942	336	19	that	that	PRON
admet-942	336	20	showed	show	VERB
admet-942	336	21	positive	positive	ADJ
admet-942	336	22	progression	progression	NOUN
admet-942	336	23	on	on	ADP
admet-942	336	24	fatty	fatty	NOUN
admet-942	336	25	liver	liver	NOUN
admet-942	336	26	recovery	recovery	NOUN
admet-942	336	27	by	by	ADP
admet-942	336	28	using	use	VERB
admet-942	336	29	known	know	VERB
admet-942	336	30	anti	anti	ADJ
admet-942	336	31	-	-	ADJ
admet-942	336	32	steatosis	steatosis	ADJ
admet-942	336	33	compounds	compound	NOUN
admet-942	336	34	.	.	PUNCT
admet-942	337	1	this	this	DET
admet-942	337	2	model	model	NOUN
admet-942	337	3	showed	show	VERB
admet-942	337	4	adipokine	adipokine	ADJ
admet-942	337	5	expression	expression	NOUN
admet-942	337	6	and	and	CCONJ
admet-942	337	7	metabolic	metabolic	NOUN
admet-942	337	8	responses	response	NOUN
admet-942	337	9	similar	similar	ADJ
admet-942	337	10	to	to	ADP
admet-942	337	11	those	those	PRON
admet-942	337	12	seen	see	VERB
admet-942	337	13	in	in	ADP
admet-942	337	14	clinical	clinical	ADJ
admet-942	337	15	non	non	ADJ
admet-942	337	16	-	-	ADJ
admet-942	337	17	alcoholic	alcoholic	ADJ
admet-942	337	18	fatty	fatty	NOUN
admet-942	337	19	liver	liver	NOUN
admet-942	337	20	disease	disease	NOUN
admet-942	337	21	.	.	PUNCT
admet-942	338	1	the	the	DET
admet-942	338	2	chip	chip	NOUN
admet-942	338	3	is	be	AUX
admet-942	338	4	not	not	PART
admet-942	338	5	designed	design	VERB
admet-942	338	6	for	for	ADP
admet-942	338	7	on	on	ADP
admet-942	338	8	-	-	PUNCT
admet-942	338	9	line	line	NOUN
admet-942	338	10	quantifications	quantification	NOUN
admet-942	338	11	and	and	CCONJ
admet-942	338	12	most	most	ADJ
admet-942	338	13	of	of	ADP
admet-942	338	14	the	the	DET
admet-942	338	15	analytical	analytical	ADJ
admet-942	338	16	determinations	determination	NOUN
admet-942	338	17	had	have	VERB
admet-942	338	18	to	to	PART
admet-942	338	19	be	be	AUX
admet-942	338	20	made	make	VERB
admet-942	338	21	after	after	ADP
admet-942	338	22	removing	remove	VERB
admet-942	338	23	the	the	DET
admet-942	338	24	microtissues	microtissue	NOUN
admet-942	338	25	from	from	ADP
admet-942	338	26	the	the	DET
admet-942	338	27	chip	chip	NOUN
admet-942	339	1	[	[	X
admet-942	339	2	108	108	NUM
admet-942	339	3	]	]	PUNCT
admet-942	339	4	.	.	PUNCT
admet-942	340	1	as	as	ADV
admet-942	340	2	well	well	ADV
admet-942	340	3	as	as	ADP
admet-942	340	4	the	the	DET
admet-942	340	5	heart	heart	NOUN
admet-942	340	6	or	or	CCONJ
admet-942	340	7	the	the	DET
admet-942	340	8	intestine	intestine	NOUN
admet-942	340	9	,	,	PUNCT
admet-942	340	10	the	the	DET
admet-942	340	11	liver	liver	NOUN
admet-942	340	12	has	have	AUX
admet-942	340	13	been	be	AUX
admet-942	340	14	studied	study	VERB
admet-942	340	15	in	in	ADP
admet-942	340	16	multiorgan	multiorgan	NOUN
admet-942	340	17	chips	chip	NOUN
admet-942	340	18	to	to	PART
admet-942	340	19	investigate	investigate	VERB
admet-942	340	20	systemic	systemic	ADJ
admet-942	340	21	effects	effect	NOUN
admet-942	340	22	,	,	PUNCT
admet-942	340	23	absorption	absorption	NOUN
admet-942	340	24	and	and	CCONJ
admet-942	340	25	metabolism	metabolism	NOUN
admet-942	341	1	[	[	X
admet-942	341	2	51,67,68	51,67,68	NUM
admet-942	341	3	]	]	PUNCT
admet-942	341	4	.	.	PUNCT
admet-942	342	1	central	central	ADJ
admet-942	342	2	nervous	nervous	ADJ
admet-942	342	3	system-	system-	NOUN
admet-942	342	4	,	,	PUNCT
admet-942	342	5	brainor	brainor	NOUN
admet-942	342	6	blood	blood	NOUN
admet-942	342	7	brain	brain	NOUN
admet-942	342	8	barrier	barrier	NOUN
admet-942	342	9	(	(	PUNCT
admet-942	342	10	bbb)-on	bbb)-on	NOUN
admet-942	342	11	-	-	PUNCT
admet-942	342	12	a	a	DET
admet-942	342	13	-	-	PUNCT
admet-942	342	14	chip	chip	NOUN
admet-942	342	15	it	it	PRON
admet-942	342	16	is	be	AUX
admet-942	342	17	possible	possible	ADJ
admet-942	342	18	to	to	PART
admet-942	342	19	simulate	simulate	VERB
admet-942	342	20	physiological	physiological	ADJ
admet-942	342	21	and	and	CCONJ
admet-942	342	22	pathological	pathological	ADJ
admet-942	342	23	mechanisms	mechanism	NOUN
admet-942	342	24	of	of	ADP
admet-942	342	25	the	the	DET
admet-942	342	26	central	central	ADJ
admet-942	342	27	nervous	nervous	ADJ
admet-942	342	28	system	system	NOUN
admet-942	342	29	(	(	PUNCT
admet-942	342	30	cns	cns	NOUN
admet-942	342	31	)	)	PUNCT
admet-942	342	32	in	in	ADP
admet-942	342	33	an	an	DET
admet-942	342	34	ooc	ooc	NOUN
admet-942	343	1	[	[	X
admet-942	343	2	2,88	2,88	NUM
admet-942	343	3	]	]	PUNCT
admet-942	343	4	.	.	PUNCT
admet-942	344	1	these	these	DET
admet-942	344	2	models	model	NOUN
admet-942	344	3	can	can	AUX
admet-942	344	4	be	be	AUX
admet-942	344	5	very	very	ADV
admet-942	344	6	useful	useful	ADJ
admet-942	344	7	considering	consider	VERB
admet-942	344	8	the	the	DET
admet-942	344	9	complexity	complexity	NOUN
admet-942	344	10	of	of	ADP
admet-942	344	11	the	the	DET
admet-942	344	12	human	human	ADJ
admet-942	344	13	brain	brain	NOUN
admet-942	344	14	,	,	PUNCT
admet-942	344	15	which	which	PRON
admet-942	344	16	makes	make	VERB
admet-942	344	17	it	it	PRON
admet-942	344	18	difficult	difficult	ADJ
admet-942	344	19	to	to	PART
admet-942	344	20	study	study	VERB
admet-942	344	21	the	the	DET
admet-942	344	22	cns	cns	NOUN
admet-942	344	23	in	in	ADP
admet-942	344	24	animal	animal	NOUN
admet-942	344	25	models	model	NOUN
admet-942	344	26	or	or	CCONJ
admet-942	344	27	2d	2d	NOUN
admet-942	344	28	cultures	culture	NOUN
admet-942	344	29	[	[	X
admet-942	344	30	13].the	13].the	DET
admet-942	344	31	blood	blood	NOUN
admet-942	344	32	-	-	PUNCT
admet-942	344	33	brain	brain	NOUN
admet-942	344	34	barrier	barrier	NOUN
admet-942	344	35	plays	play	VERB
admet-942	344	36	a	a	DET
admet-942	344	37	vital	vital	ADJ
admet-942	344	38	role	role	NOUN
admet-942	344	39	in	in	ADP
admet-942	344	40	homeostasis	homeostasis	NOUN
admet-942	344	41	and	and	CCONJ
admet-942	344	42	it	it	PRON
admet-942	344	43	is	be	AUX
admet-942	344	44	the	the	DET
admet-942	344	45	main	main	ADJ
admet-942	344	46	limitation	limitation	NOUN
admet-942	344	47	for	for	ADP
admet-942	344	48	the	the	DET
admet-942	344	49	administration	administration	NOUN
admet-942	344	50	of	of	ADP
admet-942	344	51	drugs	drug	NOUN
admet-942	344	52	in	in	ADP
admet-942	344	53	the	the	DET
admet-942	344	54	brain	brain	NOUN
admet-942	345	1	[	[	X
admet-942	345	2	109	109	NUM
admet-942	345	3	]	]	PUNCT
admet-942	345	4	.	.	PUNCT
admet-942	346	1	the	the	DET
admet-942	346	2	development	development	NOUN
admet-942	346	3	of	of	ADP
admet-942	346	4	integrated	integrate	VERB
admet-942	346	5	systems	system	NOUN
admet-942	346	6	reproducing	reproduce	VERB
admet-942	346	7	the	the	DET
admet-942	346	8	barrier	barrier	NOUN
admet-942	346	9	properties	property	NOUN
admet-942	346	10	and	and	CCONJ
admet-942	346	11	modelling	model	VERB
admet-942	346	12	inter	inter	ADJ
admet-942	346	13	-	-	ADJ
admet-942	346	14	individual	individual	ADJ
admet-942	346	15	variation	variation	NOUN
admet-942	346	16	[	[	X
admet-942	346	17	2,15,74	2,15,74	NUM
admet-942	346	18	]	]	PUNCT
admet-942	346	19	makes	make	VERB
admet-942	346	20	it	it	PRON
admet-942	346	21	possible	possible	ADJ
admet-942	346	22	to	to	PART
admet-942	346	23	assess	assess	VERB
admet-942	346	24	whether	whether	SCONJ
admet-942	346	25	a	a	DET
admet-942	346	26	drug	drug	NOUN
admet-942	346	27	designed	design	VERB
admet-942	346	28	to	to	PART
admet-942	346	29	treat	treat	VERB
admet-942	346	30	a	a	DET
admet-942	346	31	neuro	neuro	NOUN
admet-942	346	32	-	-	PUNCT
admet-942	346	33	related	relate	VERB
admet-942	346	34	disease	disease	NOUN
admet-942	346	35	can	can	AUX
admet-942	346	36	actually	actually	ADV
admet-942	346	37	reach	reach	VERB
admet-942	346	38	its	its	PRON
admet-942	346	39	therapeutic	therapeutic	ADJ
admet-942	346	40	target	target	NOUN
admet-942	347	1	[	[	X
admet-942	347	2	13,78	13,78	NUM
admet-942	347	3	]	]	PUNCT
admet-942	347	4	.	.	PUNCT
admet-942	348	1	adriani	adriani	PROPN
admet-942	348	2	et	et	PROPN
admet-942	348	3	al	al	PROPN
admet-942	348	4	.	.	PROPN
admet-942	348	5	were	be	AUX
admet-942	348	6	able	able	ADJ
admet-942	348	7	to	to	PART
admet-942	348	8	develop	develop	VERB
admet-942	348	9	a	a	DET
admet-942	348	10	chip	chip	NOUN
admet-942	348	11	with	with	ADP
admet-942	348	12	neurons	neuron	NOUN
admet-942	348	13	and	and	CCONJ
admet-942	348	14	astrocytes	astrocyte	NOUN
admet-942	348	15	that	that	PRON
admet-942	348	16	showed	show	VERB
admet-942	348	17	adequate	adequate	ADJ
admet-942	348	18	morphology	morphology	NOUN
admet-942	348	19	,	,	PUNCT
admet-942	348	20	growth	growth	NOUN
admet-942	348	21	and	and	CCONJ
admet-942	348	22	vascular	vascular	ADJ
admet-942	348	23	function	function	NOUN
admet-942	348	24	,	,	PUNCT
admet-942	348	25	identifying	identify	VERB
admet-942	348	26	the	the	DET
admet-942	348	27	opportunity	opportunity	NOUN
admet-942	348	28	to	to	PART
admet-942	348	29	include	include	VERB
admet-942	348	30	other	other	ADJ
admet-942	348	31	types	type	NOUN
admet-942	348	32	of	of	ADP
admet-942	348	33	cells	cell	NOUN
admet-942	348	34	such	such	ADJ
admet-942	348	35	as	as	ADP
admet-942	348	36	pericytes	pericyte	NOUN
admet-942	348	37	and	and	CCONJ
admet-942	348	38	microglia	microglia	NOUN
admet-942	348	39	,	,	PUNCT
admet-942	348	40	which	which	PRON
admet-942	348	41	increased	increase	VERB
admet-942	348	42	the	the	DET
admet-942	348	43	model	model	NOUN
admet-942	348	44	’s	’s	PART
admet-942	348	45	potential	potential	NOUN
admet-942	348	46	to	to	PART
admet-942	348	47	be	be	AUX
admet-942	348	48	used	use	VERB
admet-942	348	49	for	for	ADP
admet-942	348	50	neurovascular	neurovascular	ADJ
admet-942	348	51	studies	study	NOUN
admet-942	348	52	and	and	CCONJ
admet-942	348	53	too	too	ADV
admet-942	348	54	assess	assess	VERB
admet-942	348	55	drug	drug	NOUN
admet-942	348	56	effects	effect	NOUN
admet-942	348	57	on	on	ADP
admet-942	348	58	brain	brain	NOUN
admet-942	348	59	neural	neural	ADJ
admet-942	348	60	function	function	NOUN
admet-942	348	61	[	[	X
admet-942	348	62	48	48	NUM
admet-942	348	63	]	]	PUNCT
admet-942	348	64	.	.	PUNCT
admet-942	349	1	the	the	DET
admet-942	349	2	brain	brain	NOUN
admet-942	349	3	endothelium	endothelium	NOUN
admet-942	349	4	created	create	VERB
admet-942	349	5	from	from	ADP
admet-942	349	6	primary	primary	ADJ
admet-942	349	7	patient	patient	NOUN
admet-942	349	8	cells	cell	NOUN
admet-942	349	9	by	by	ADP
admet-942	349	10	vatine	vatine	NOUN
admet-942	349	11	et	et	PROPN
admet-942	349	12	al	al	PROPN
admet-942	349	13	.	.	PROPN
admet-942	349	14	reproduced	reproduce	VERB
admet-942	349	15	complex	complex	ADJ
admet-942	349	16	bbb	bbb	NOUN
admet-942	349	17	functions	function	NOUN
admet-942	349	18	with	with	ADP
admet-942	349	19	the	the	DET
admet-942	349	20	potential	potential	ADJ
admet-942	349	21	applications	application	NOUN
admet-942	349	22	of	of	ADP
admet-942	349	23	drug	drug	NOUN
admet-942	349	24	screening	screening	NOUN
admet-942	349	25	and	and	CCONJ
admet-942	349	26	personalized	personalized	ADJ
admet-942	349	27	medicine	medicine	NOUN
admet-942	349	28	,	,	PUNCT
admet-942	349	29	using	use	VERB
admet-942	349	30	immunocytochemistry	immunocytochemistry	NOUN
admet-942	349	31	,	,	PUNCT
admet-942	349	32	confocal	confocal	ADJ
admet-942	349	33	microscopy	microscopy	NOUN
admet-942	349	34	,	,	PUNCT
admet-942	349	35	calcium	calcium	NOUN
admet-942	349	36	imaging	imaging	NOUN
admet-942	349	37	and	and	CCONJ
admet-942	349	38	mass	mass	ADJ
admet-942	349	39	chromatography	chromatography	NOUN
admet-942	349	40	as	as	ADP
admet-942	349	41	analytical	analytical	ADJ
admet-942	349	42	methods	method	NOUN
admet-942	349	43	,	,	PUNCT
admet-942	349	44	among	among	ADP
admet-942	349	45	others	other	NOUN
admet-942	349	46	[	[	X
admet-942	349	47	74	74	NUM
admet-942	349	48	]	]	PUNCT
admet-942	349	49	.	.	PUNCT
admet-942	350	1	tu	tu	PROPN
admet-942	350	2	et	et	PROPN
admet-942	350	3	al	al	PROPN
admet-942	350	4	.	.	PROPN
admet-942	350	5	developed	develop	VERB
admet-942	350	6	a	a	DET
admet-942	350	7	bbb	bbb	NOUN
admet-942	350	8	system	system	NOUN
admet-942	350	9	that	that	PRON
admet-942	350	10	incorporated	incorporate	VERB
admet-942	350	11	transendothelial	transendothelial	ADJ
admet-942	350	12	electrical	electrical	ADJ
admet-942	350	13	resistance	resistance	NOUN
admet-942	350	14	(	(	PUNCT
admet-942	350	15	teer	teer	NOUN
admet-942	350	16	)	)	PUNCT
admet-942	350	17	micro	micro	NOUN
admet-942	350	18	-	-	NOUN
admet-942	350	19	electrodes	electrode	NOUN
admet-942	350	20	to	to	PART
admet-942	350	21	monitor	monitor	VERB
admet-942	350	22	cell	cell	NOUN
admet-942	350	23	growth	growth	NOUN
admet-942	350	24	and	and	CCONJ
admet-942	350	25	response	response	NOUN
admet-942	350	26	in	in	ADP
admet-942	350	27	the	the	DET
admet-942	350	28	presence	presence	NOUN
admet-942	350	29	of	of	ADP
admet-942	350	30	drugs	drug	NOUN
admet-942	350	31	(	(	PUNCT
admet-942	350	32	figure	figure	NOUN
admet-942	350	33	9	9	NUM
admet-942	350	34	)	)	PUNCT
admet-942	351	1	[	[	X
admet-942	351	2	123	123	NUM
admet-942	351	3	]	]	PUNCT
admet-942	351	4	.	.	PUNCT
admet-942	352	1	admet	admet	PROPN
admet-942	352	2	&	&	CCONJ
admet-942	352	3	dmpk	dmpk	PROPN
admet-942	352	4	9(2	9(2	NUM
admet-942	352	5	)	)	PUNCT
admet-942	352	6	(	(	PUNCT
admet-942	352	7	2021	2021	NUM
admet-942	352	8	)	)	PUNCT
admet-942	352	9	111	111	NUM
admet-942	352	10	-	-	SYM
admet-942	352	11	141	141	NUM
admet-942	352	12	organ	organ	NOUN
admet-942	352	13	-	-	PUNCT
admet-942	352	14	on	on	ADP
admet-942	352	15	-	-	PUNCT
admet-942	352	16	a	a	DET
admet-942	352	17	-	-	PUNCT
admet-942	352	18	chip	chip	NOUN
admet-942	352	19	systems	system	NOUN
admet-942	352	20	for	for	ADP
admet-942	352	21	new	new	ADJ
admet-942	352	22	drugs	drug	NOUN
admet-942	352	23	development	development	NOUN
admet-942	352	24	doi	doi	PROPN
admet-942	352	25	:	:	PUNCT
admet-942	352	26	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	352	27	125	125	NUM
admet-942	352	28	figure	figure	NOUN
admet-942	352	29	8	8	NUM
admet-942	352	30	.	.	PUNCT
admet-942	353	1	schematic	schematic	ADJ
admet-942	353	2	examples	example	NOUN
admet-942	353	3	of	of	ADP
admet-942	353	4	liver	liver	NOUN
admet-942	353	5	-	-	PUNCT
admet-942	353	6	on	on	ADP
admet-942	353	7	-	-	PUNCT
admet-942	353	8	a	a	DET
admet-942	353	9	-	-	PUNCT
admet-942	353	10	chip	chip	NOUN
admet-942	353	11	devices	device	NOUN
admet-942	353	12	.	.	PUNCT
admet-942	354	1	a	a	PRON
admet-942	354	2	)	)	PUNCT
admet-942	354	3	multichannel	multichannel	NOUN
admet-942	354	4	ooc	ooc	NOUN
admet-942	354	5	.	.	PUNCT
admet-942	355	1	representation	representation	NOUN
admet-942	355	2	of	of	ADP
admet-942	355	3	a	a	DET
admet-942	355	4	i	i	NOUN
admet-942	355	5	)	)	PUNCT
admet-942	355	6	microfluidic	microfluidic	ADJ
admet-942	355	7	device	device	NOUN
admet-942	355	8	with	with	ADP
admet-942	355	9	several	several	ADJ
admet-942	355	10	channels	channel	NOUN
admet-942	355	11	of	of	ADP
admet-942	355	12	different	different	ADJ
admet-942	355	13	compositions	composition	NOUN
admet-942	355	14	for	for	ADP
admet-942	355	15	the	the	DET
admet-942	355	16	formation	formation	NOUN
admet-942	355	17	of	of	ADP
admet-942	355	18	encapsulated	encapsulate	VERB
admet-942	355	19	hepatic	hepatic	ADJ
admet-942	355	20	plate	plate	NOUN
admet-942	355	21	structures	structure	NOUN
admet-942	355	22	,	,	PUNCT
admet-942	355	23	and	and	CCONJ
admet-942	355	24	a	a	DET
admet-942	355	25	ii	ii	NOUN
admet-942	355	26	)	)	PUNCT
admet-942	355	27	system	system	NOUN
admet-942	355	28	of	of	ADP
admet-942	355	29	syringe	syringe	NOUN
admet-942	355	30	pumps	pump	NOUN
admet-942	355	31	supplying	supply	VERB
admet-942	355	32	the	the	DET
admet-942	355	33	microfluidic	microfluidic	ADJ
admet-942	355	34	channels	channel	NOUN
admet-942	355	35	of	of	ADP
admet-942	355	36	the	the	DET
admet-942	355	37	ooc	ooc	NOUN
admet-942	355	38	with	with	ADP
admet-942	355	39	solutions	solution	NOUN
admet-942	355	40	.	.	PUNCT
admet-942	356	1	adapted	adapt	VERB
admet-942	356	2	from	from	ADP
admet-942	356	3	[	[	X
admet-942	356	4	43	43	NUM
admet-942	356	5	]	]	PUNCT
admet-942	356	6	under	under	ADP
admet-942	356	7	terms	term	NOUN
admet-942	356	8	of	of	ADP
admet-942	356	9	the	the	DET
admet-942	356	10	creative	creative	ADJ
admet-942	356	11	commons	common	NOUN
admet-942	356	12	attribution	attribution	NOUN
admet-942	356	13	license	license	NOUN
admet-942	356	14	.	.	PUNCT
admet-942	357	1	copyright	copyright	NOUN
admet-942	357	2	(	(	PUNCT
admet-942	357	3	2020	2020	NUM
admet-942	357	4	)	)	PUNCT
admet-942	357	5	.	.	PUNCT
admet-942	358	1	b	b	X
admet-942	358	2	)	)	PUNCT
admet-942	358	3	diagram	diagram	NOUN
admet-942	358	4	of	of	ADP
admet-942	358	5	a	a	DET
admet-942	358	6	pressure	pressure	NOUN
admet-942	358	7	-	-	PUNCT
admet-942	358	8	driven	drive	VERB
admet-942	358	9	flow	flow	NOUN
admet-942	358	10	control	control	NOUN
admet-942	358	11	system	system	NOUN
admet-942	358	12	of	of	ADP
admet-942	358	13	a	a	DET
admet-942	358	14	3d	3d	NUM
admet-942	358	15	liver	liver	NOUN
admet-942	358	16	bioreactor	bioreactor	NOUN
admet-942	358	17	for	for	ADP
admet-942	358	18	hepatotoxicity	hepatotoxicity	NOUN
admet-942	358	19	testing	testing	NOUN
admet-942	358	20	under	under	ADP
admet-942	358	21	perfusion	perfusion	NOUN
admet-942	358	22	conditions	condition	NOUN
admet-942	358	23	.	.	PUNCT
admet-942	359	1	adapted	adapt	VERB
admet-942	359	2	from	from	ADP
admet-942	359	3	[	[	X
admet-942	359	4	107	107	NUM
admet-942	359	5	]	]	PUNCT
admet-942	359	6	under	under	ADP
admet-942	359	7	terms	term	NOUN
admet-942	359	8	of	of	ADP
admet-942	359	9	the	the	DET
admet-942	359	10	creative	creative	ADJ
admet-942	359	11	commons	common	NOUN
admet-942	359	12	attribution	attribution	NOUN
admet-942	359	13	license	license	NOUN
admet-942	359	14	.	.	PUNCT
admet-942	360	1	copyright	copyright	NOUN
admet-942	360	2	(	(	PUNCT
admet-942	360	3	2018	2018	NUM
admet-942	360	4	)	)	PUNCT
admet-942	360	5	.	.	PUNCT
admet-942	361	1	figure	figure	NOUN
admet-942	361	2	9	9	NUM
admet-942	361	3	.	.	PUNCT
admet-942	362	1	bbb	bbb	NOUN
admet-942	362	2	-	-	PUNCT
admet-942	362	3	on	on	ADP
admet-942	362	4	-	-	PUNCT
admet-942	362	5	a	a	DET
admet-942	362	6	-	-	PUNCT
admet-942	362	7	chip	chip	NOUN
admet-942	362	8	with	with	ADP
admet-942	362	9	microelectrodes	microelectrode	NOUN
admet-942	362	10	incorporated	incorporate	VERB
admet-942	362	11	.	.	PUNCT
admet-942	363	1	a	a	DET
admet-942	363	2	)	)	PUNCT
admet-942	363	3	diagram	diagram	NOUN
admet-942	363	4	of	of	ADP
admet-942	363	5	the	the	DET
admet-942	363	6	main	main	ADJ
admet-942	363	7	channel	channel	NOUN
admet-942	363	8	.	.	PUNCT
admet-942	364	1	b	b	X
admet-942	364	2	)	)	PUNCT
admet-942	364	3	diagram	diagram	NOUN
admet-942	364	4	of	of	ADP
admet-942	364	5	the	the	DET
admet-942	364	6	electrodes	electrode	NOUN
admet-942	364	7	and	and	CCONJ
admet-942	364	8	the	the	DET
admet-942	364	9	chip	chip	NOUN
admet-942	364	10	structure	structure	NOUN
admet-942	364	11	.	.	PUNCT
admet-942	365	1	c	c	X
admet-942	365	2	)	)	PUNCT
admet-942	365	3	photograph	photograph	NOUN
admet-942	365	4	of	of	ADP
admet-942	365	5	the	the	DET
admet-942	365	6	integrated	integrate	VERB
admet-942	365	7	system	system	NOUN
admet-942	365	8	.	.	PUNCT
admet-942	366	1	adapted	adapt	VERB
admet-942	366	2	from	from	ADP
admet-942	366	3	[	[	X
admet-942	366	4	123	123	NUM
admet-942	366	5	]	]	PUNCT
admet-942	366	6	under	under	ADP
admet-942	366	7	terms	term	NOUN
admet-942	366	8	of	of	ADP
admet-942	366	9	the	the	DET
admet-942	366	10	creative	creative	ADJ
admet-942	366	11	commons	common	NOUN
admet-942	366	12	attribution	attribution	NOUN
admet-942	366	13	license	license	NOUN
admet-942	366	14	.	.	PUNCT
admet-942	367	1	copyright	copyright	NOUN
admet-942	367	2	(	(	PUNCT
admet-942	367	3	2020	2020	NUM
admet-942	367	4	)	)	PUNCT
admet-942	367	5	.	.	PUNCT
admet-942	368	1	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	368	2	r.	r.	PROPN
admet-942	368	3	vargas	vargas	PROPN
admet-942	368	4	,	,	PUNCT
admet-942	368	5	a.	a.	NOUN
admet-942	368	6	egurbide	egurbide	NOUN
admet-942	368	7	-	-	PUNCT
admet-942	368	8	sifre	sifre	NOUN
admet-942	368	9	and	and	CCONJ
admet-942	368	10	l.	l.	PROPN
admet-942	368	11	medina	medina	PROPN
admet-942	368	12	admet	admet	PROPN
admet-942	368	13	&	&	CCONJ
admet-942	368	14	dmpk	dmpk	PROPN
admet-942	368	15	9(2	9(2	NUM
admet-942	368	16	)	)	PUNCT
admet-942	368	17	(	(	PUNCT
admet-942	368	18	2021	2021	NUM
admet-942	368	19	)	)	PUNCT
admet-942	368	20	111	111	NUM
admet-942	368	21	-	-	SYM
admet-942	368	22	141	141	NUM
admet-942	368	23	126	126	NUM
admet-942	368	24	table	table	NOUN
admet-942	368	25	4	4	NUM
admet-942	368	26	.	.	PUNCT
admet-942	368	27	main	main	ADJ
admet-942	368	28	pathological	pathological	ADJ
admet-942	368	29	conditions	condition	NOUN
admet-942	368	30	simulated	simulate	VERB
admet-942	368	31	in	in	ADP
admet-942	368	32	ooc	ooc	NOUN
admet-942	368	33	systems	system	NOUN
admet-942	368	34	pathology	pathology	NOUN
admet-942	368	35	references	reference	NOUN
admet-942	368	36	cancer	cancer	NOUN
admet-942	369	1	[	[	X
admet-942	369	2	13–15,23,42,50,63,122,124–127	13–15,23,42,50,63,122,124–127	NUM
admet-942	369	3	]	]	X
admet-942	369	4	inflammation	inflammation	NOUN
admet-942	369	5	[	[	X
admet-942	369	6	7,128–130	7,128–130	X
admet-942	369	7	]	]	X
admet-942	369	8	epilepsy	epilepsy	NOUN
admet-942	370	1	[	[	X
admet-942	370	2	44	44	NUM
admet-942	370	3	]	]	PUNCT
admet-942	371	1	[	[	X
admet-942	371	2	64	64	NUM
admet-942	371	3	]	]	PUNCT
admet-942	371	4	alzheimer	alzheimer	PROPN
admet-942	371	5	's	's	PART
admet-942	371	6	disease	disease	NOUN
admet-942	371	7	[	[	X
admet-942	371	8	64	64	NUM
admet-942	371	9	]	]	PUNCT
admet-942	371	10	musculoskeletal	musculoskeletal	ADJ
admet-942	371	11	abnormalities	abnormality	NOUN
admet-942	371	12	[	[	X
admet-942	371	13	23	23	NUM
admet-942	371	14	]	]	PUNCT
admet-942	371	15	arthritis	arthritis	NOUN
admet-942	372	1	[	[	X
admet-942	372	2	23	23	NUM
admet-942	372	3	]	]	PUNCT
admet-942	372	4	arrhythmias	arrhythmia	VERB
admet-942	372	5	[	[	X
admet-942	372	6	44	44	NUM
admet-942	372	7	]	]	PUNCT
admet-942	372	8	diabetes	diabetes	NOUN
admet-942	372	9	[	[	X
admet-942	372	10	102	102	NUM
admet-942	372	11	]	]	X
admet-942	372	12	hematological	hematological	ADJ
admet-942	372	13	diseases	disease	NOUN
admet-942	373	1	[	[	X
admet-942	373	2	23	23	NUM
admet-942	373	3	]	]	PUNCT
admet-942	373	4	pneumonia	pneumonia	NOUN
admet-942	373	5	[	[	X
admet-942	373	6	44	44	NUM
admet-942	373	7	]	]	X
admet-942	373	8	parkinson	parkinson	NOUN
admet-942	373	9	[	[	X
admet-942	373	10	64	64	NUM
admet-942	373	11	]	]	SYM
admet-942	373	12	thrombosis	thrombosis	NOUN
admet-942	373	13	[	[	X
admet-942	373	14	23	23	NUM
admet-942	373	15	]	]	X
admet-942	373	16	inflammation	inflammation	NOUN
admet-942	373	17	-	-	PUNCT
admet-942	373	18	on	on	ADP
admet-942	373	19	-	-	PUNCT
admet-942	373	20	a	a	DET
admet-942	373	21	-	-	PUNCT
admet-942	373	22	chip	chip	NOUN
admet-942	373	23	,	,	PUNCT
admet-942	373	24	or	or	CCONJ
admet-942	373	25	immune	immune	ADJ
admet-942	373	26	system	system	NOUN
admet-942	373	27	-	-	PUNCT
admet-942	373	28	on	on	ADP
admet-942	373	29	-	-	PUNCT
admet-942	373	30	a	a	DET
admet-942	373	31	-	-	PUNCT
admet-942	373	32	chip	chip	NOUN
admet-942	373	33	ooc	ooc	NOUN
admet-942	373	34	can	can	AUX
admet-942	373	35	also	also	ADV
admet-942	373	36	reproduce	reproduce	VERB
admet-942	373	37	complex	complex	ADJ
admet-942	373	38	physiological	physiological	ADJ
admet-942	373	39	events	event	NOUN
admet-942	373	40	or	or	CCONJ
admet-942	373	41	multi	multi	ADJ
admet-942	373	42	-	-	ADJ
admet-942	373	43	organ	organ	ADJ
admet-942	373	44	functions	function	NOUN
admet-942	373	45	[	[	X
admet-942	373	46	7,128	7,128	NUM
admet-942	373	47	]	]	PUNCT
admet-942	373	48	.	.	PUNCT
admet-942	374	1	the	the	DET
admet-942	374	2	development	development	NOUN
admet-942	374	3	of	of	ADP
admet-942	374	4	the	the	DET
admet-942	374	5	inflammatory	inflammatory	ADJ
admet-942	374	6	system	system	NOUN
admet-942	374	7	-	-	PUNCT
admet-942	374	8	on	on	ADP
admet-942	374	9	-	-	PUNCT
admet-942	374	10	a	a	DET
admet-942	374	11	-	-	PUNCT
admet-942	374	12	chip	chip	NOUN
admet-942	374	13	enables	enable	VERB
admet-942	374	14	a	a	DET
admet-942	374	15	better	well	ADJ
admet-942	374	16	understanding	understanding	NOUN
admet-942	374	17	of	of	ADP
admet-942	374	18	how	how	SCONJ
admet-942	374	19	immune	immune	ADJ
admet-942	374	20	system	system	NOUN
admet-942	374	21	cells	cell	NOUN
admet-942	374	22	synchronize	synchronize	VERB
admet-942	374	23	their	their	PRON
admet-942	374	24	activities	activity	NOUN
admet-942	374	25	to	to	PART
admet-942	374	26	fight	fight	VERB
admet-942	374	27	a	a	DET
admet-942	374	28	disease	disease	NOUN
admet-942	374	29	.	.	PUNCT
admet-942	375	1	the	the	DET
admet-942	375	2	evaluation	evaluation	NOUN
admet-942	375	3	of	of	ADP
admet-942	375	4	the	the	DET
admet-942	375	5	coordinated	coordinate	VERB
admet-942	375	6	cellular	cellular	ADJ
admet-942	375	7	activities	activity	NOUN
admet-942	375	8	related	relate	VERB
admet-942	375	9	to	to	ADP
admet-942	375	10	inflammation	inflammation	NOUN
admet-942	375	11	could	could	AUX
admet-942	375	12	have	have	VERB
admet-942	375	13	interesting	interesting	ADJ
admet-942	375	14	biological	biological	ADJ
admet-942	375	15	and	and	CCONJ
admet-942	375	16	clinical	clinical	ADJ
admet-942	375	17	applications	application	NOUN
admet-942	375	18	[	[	X
admet-942	375	19	128	128	NUM
admet-942	375	20	]	]	PUNCT
admet-942	375	21	.	.	PUNCT
admet-942	376	1	autoimmune	autoimmune	ADJ
admet-942	376	2	diseases	disease	NOUN
admet-942	376	3	or	or	CCONJ
admet-942	376	4	immunity	immunity	NOUN
admet-942	376	5	generated	generate	VERB
admet-942	376	6	by	by	ADP
admet-942	376	7	vaccines	vaccine	NOUN
admet-942	376	8	can	can	AUX
admet-942	376	9	also	also	ADV
admet-942	376	10	be	be	AUX
admet-942	376	11	assessed	assess	VERB
admet-942	376	12	by	by	ADP
admet-942	376	13	ooc	ooc	NOUN
admet-942	376	14	systems	system	NOUN
admet-942	376	15	[	[	X
admet-942	376	16	50,71,102	50,71,102	NUM
admet-942	376	17	]	]	X
admet-942	376	18	.	.	PUNCT
admet-942	377	1	sharifi	sharifi	PROPN
admet-942	377	2	et	et	PROPN
admet-942	377	3	al	al	PROPN
admet-942	377	4	.	.	PROPN
admet-942	377	5	developed	develop	VERB
admet-942	377	6	a	a	DET
admet-942	377	7	system	system	NOUN
admet-942	377	8	on	on	ADP
admet-942	377	9	a	a	DET
admet-942	377	10	chip	chip	NOUN
admet-942	377	11	for	for	ADP
admet-942	377	12	modeling	model	VERB
admet-942	377	13	the	the	DET
admet-942	377	14	immune	immune	ADJ
admet-942	377	15	response	response	NOUN
admet-942	377	16	cascade	cascade	NOUN
admet-942	377	17	of	of	ADP
admet-942	377	18	events	event	NOUN
admet-942	377	19	during	during	ADP
admet-942	377	20	immune	immune	ADJ
admet-942	377	21	cell	cell	NOUN
admet-942	377	22	response	response	NOUN
admet-942	377	23	to	to	ADP
admet-942	377	24	implants	implant	NOUN
admet-942	377	25	[	[	X
admet-942	377	26	130	130	NUM
admet-942	377	27	]	]	PUNCT
admet-942	377	28	,	,	PUNCT
admet-942	377	29	and	and	CCONJ
admet-942	377	30	goyal	goyal	AUX
admet-942	377	31	et	et	PROPN
admet-942	377	32	al	al	PROPN
admet-942	377	33	.	.	PROPN
admet-942	377	34	described	describe	VERB
admet-942	377	35	a	a	DET
admet-942	377	36	microfluidic	microfluidic	ADJ
admet-942	377	37	chip	chip	NOUN
admet-942	377	38	for	for	ADP
admet-942	377	39	evaluation	evaluation	NOUN
admet-942	377	40	of	of	ADP
admet-942	377	41	vaccine	vaccine	NOUN
admet-942	377	42	response	response	NOUN
admet-942	377	43	that	that	PRON
admet-942	377	44	was	be	AUX
admet-942	377	45	able	able	ADJ
admet-942	377	46	to	to	PART
admet-942	377	47	obtain	obtain	VERB
admet-942	377	48	antibodies	antibody	NOUN
admet-942	377	49	and	and	CCONJ
admet-942	377	50	can	can	AUX
admet-942	377	51	be	be	AUX
admet-942	377	52	useful	useful	ADJ
admet-942	377	53	for	for	ADP
admet-942	377	54	immunotherapy	immunotherapy	NOUN
admet-942	377	55	candidate	candidate	NOUN
admet-942	377	56	selection	selection	NOUN
admet-942	377	57	[	[	X
admet-942	377	58	130	130	NUM
admet-942	377	59	]	]	PUNCT
admet-942	377	60	.	.	PUNCT
admet-942	378	1	gopalakrishnan	gopalakrishnan	NOUN
admet-942	378	2	et	et	PROPN
admet-942	378	3	al	al	PROPN
admet-942	378	4	.	.	PROPN
admet-942	378	5	worked	work	VERB
admet-942	378	6	on	on	ADP
admet-942	378	7	a	a	DET
admet-942	378	8	real	real	ADJ
admet-942	378	9	-	-	PUNCT
admet-942	378	10	time	time	NOUN
admet-942	378	11	continuous	continuous	ADJ
admet-942	378	12	monitoring	monitoring	NOUN
admet-942	378	13	chip	chip	NOUN
admet-942	378	14	(	(	PUNCT
admet-942	378	15	using	use	VERB
admet-942	378	16	microscopy	microscopy	NOUN
admet-942	378	17	and	and	CCONJ
admet-942	378	18	fluorescence	fluorescence	NOUN
admet-942	378	19	)	)	PUNCT
admet-942	378	20	for	for	ADP
admet-942	378	21	studying	study	VERB
admet-942	378	22	cellular	cellular	ADJ
admet-942	378	23	migration	migration	NOUN
admet-942	378	24	and	and	CCONJ
admet-942	378	25	organization	organization	NOUN
admet-942	378	26	during	during	ADP
admet-942	378	27	inflammatory	inflammatory	ADJ
admet-942	378	28	processes	process	NOUN
admet-942	378	29	in	in	ADP
admet-942	378	30	response	response	NOUN
admet-942	378	31	to	to	ADP
admet-942	378	32	simulated	simulated	ADJ
admet-942	378	33	cytokine	cytokine	ADJ
admet-942	378	34	gradients	gradient	NOUN
admet-942	378	35	(	(	PUNCT
admet-942	378	36	figure	figure	NOUN
admet-942	378	37	10	10	NUM
admet-942	378	38	)	)	PUNCT
admet-942	379	1	[	[	X
admet-942	379	2	131	131	NUM
admet-942	379	3	]	]	PUNCT
admet-942	379	4	.	.	PUNCT
admet-942	380	1	figure	figure	NOUN
admet-942	380	2	10	10	NUM
admet-942	380	3	.	.	PUNCT
admet-942	381	1	microfluidic	microfluidic	ADJ
admet-942	381	2	device	device	NOUN
admet-942	381	3	allowing	allow	VERB
admet-942	381	4	cell	cell	NOUN
admet-942	381	5	migration	migration	NOUN
admet-942	381	6	.	.	PUNCT
admet-942	382	1	a	a	DET
admet-942	382	2	)	)	PUNCT
admet-942	382	3	simulation	simulation	NOUN
admet-942	382	4	of	of	ADP
admet-942	382	5	an	an	DET
admet-942	382	6	in	in	ADP
admet-942	382	7	vivo	vivo	ADJ
admet-942	382	8	scenario	scenario	NOUN
admet-942	382	9	with	with	ADP
admet-942	382	10	the	the	DET
admet-942	382	11	chip	chip	NOUN
admet-942	382	12	construction	construction	NOUN
admet-942	382	13	.	.	PUNCT
admet-942	383	1	b	b	X
admet-942	383	2	)	)	PUNCT
admet-942	383	3	schematic	schematic	ADJ
admet-942	383	4	of	of	ADP
admet-942	383	5	the	the	DET
admet-942	383	6	device	device	NOUN
admet-942	383	7	’s	’s	PART
admet-942	383	8	manufacture	manufacture	NOUN
admet-942	383	9	by	by	ADP
admet-942	383	10	soft	soft	ADJ
admet-942	383	11	lithography	lithography	NOUN
admet-942	383	12	.	.	PUNCT
admet-942	384	1	reproduced	reproduce	VERB
admet-942	384	2	from	from	ADP
admet-942	384	3	[	[	X
admet-942	384	4	131	131	NUM
admet-942	384	5	]	]	PUNCT
admet-942	384	6	with	with	ADP
admet-942	384	7	permission	permission	NOUN
admet-942	384	8	from	from	ADP
admet-942	384	9	the	the	DET
admet-942	384	10	royal	royal	ADJ
admet-942	384	11	society	society	NOUN
admet-942	384	12	of	of	ADP
admet-942	384	13	chemistry	chemistry	NOUN
admet-942	384	14	.	.	PUNCT
admet-942	385	1	copyright	copyright	NOUN
admet-942	385	2	(	(	PUNCT
admet-942	385	3	2015	2015	NUM
admet-942	385	4	)	)	PUNCT
admet-942	385	5	.	.	PUNCT
admet-942	386	1	cancer	cancer	NOUN
admet-942	386	2	-	-	PUNCT
admet-942	386	3	on	on	ADP
admet-942	386	4	-	-	PUNCT
admet-942	386	5	a	a	DET
admet-942	386	6	-	-	PUNCT
admet-942	386	7	chip	chip	NOUN
admet-942	386	8	cancer	cancer	NOUN
admet-942	386	9	models	model	NOUN
admet-942	386	10	in	in	ADP
admet-942	386	11	mice	mouse	NOUN
admet-942	386	12	have	have	AUX
admet-942	386	13	resulted	result	VERB
admet-942	386	14	in	in	ADP
admet-942	386	15	countless	countless	ADJ
admet-942	386	16	treatments	treatment	NOUN
admet-942	386	17	to	to	PART
admet-942	386	18	cure	cure	VERB
admet-942	386	19	cancer	cancer	NOUN
admet-942	386	20	in	in	ADP
admet-942	386	21	the	the	DET
admet-942	386	22	animals	animal	NOUN
admet-942	386	23	,	,	PUNCT
admet-942	386	24	although	although	SCONJ
admet-942	386	25	they	they	PRON
admet-942	386	26	present	present	VERB
admet-942	386	27	an	an	DET
admet-942	386	28	alarming	alarming	ADJ
admet-942	386	29	difficulty	difficulty	NOUN
admet-942	386	30	to	to	PART
admet-942	386	31	transfer	transfer	VERB
admet-942	386	32	these	these	DET
admet-942	386	33	results	result	NOUN
admet-942	386	34	to	to	ADP
admet-942	386	35	humans	human	NOUN
admet-942	386	36	.	.	PUNCT
admet-942	387	1	ooc	ooc	NOUN
admet-942	387	2	systems	system	NOUN
admet-942	387	3	provide	provide	VERB
admet-942	387	4	the	the	DET
admet-942	387	5	possibility	possibility	NOUN
admet-942	387	6	to	to	PART
admet-942	387	7	study	study	VERB
admet-942	387	8	the	the	DET
admet-942	387	9	physio	physio	NOUN
admet-942	387	10	-	-	PUNCT
admet-942	387	11	pathological	pathological	ADJ
admet-942	387	12	mechanisms	mechanism	NOUN
admet-942	387	13	and	and	CCONJ
admet-942	387	14	the	the	DET
admet-942	387	15	resistance	resistance	NOUN
admet-942	387	16	reactions	reaction	NOUN
admet-942	387	17	in	in	ADP
admet-942	387	18	an	an	DET
admet-942	387	19	environment	environment	NOUN
admet-942	387	20	almost	almost	ADV
admet-942	387	21	identical	identical	ADJ
admet-942	387	22	not	not	PART
admet-942	387	23	only	only	ADV
admet-942	387	24	to	to	ADP
admet-942	387	25	human	human	ADJ
admet-942	387	26	disease	disease	NOUN
admet-942	387	27	but	but	CCONJ
admet-942	387	28	to	to	ADP
admet-942	387	29	the	the	DET
admet-942	387	30	specific	specific	ADJ
admet-942	387	31	individual	individual	NOUN
admet-942	387	32	.	.	PUNCT
admet-942	388	1	therefore	therefore	ADV
admet-942	388	2	,	,	PUNCT
admet-942	388	3	these	these	DET
admet-942	388	4	systems	system	NOUN
admet-942	388	5	can	can	AUX
admet-942	388	6	open	open	VERB
admet-942	388	7	the	the	DET
admet-942	388	8	door	door	NOUN
admet-942	388	9	to	to	ADP
admet-942	388	10	many	many	ADJ
admet-942	388	11	treatments	treatment	NOUN
admet-942	388	12	against	against	ADP
admet-942	388	13	cancer	cancer	NOUN
admet-942	388	14	[	[	X
admet-942	388	15	13,14	13,14	NUM
admet-942	388	16	]	]	PUNCT
admet-942	388	17	.	.	PUNCT
admet-942	389	1	admet	admet	PROPN
admet-942	389	2	&	&	CCONJ
admet-942	389	3	dmpk	dmpk	PROPN
admet-942	389	4	9(2	9(2	NUM
admet-942	389	5	)	)	PUNCT
admet-942	389	6	(	(	PUNCT
admet-942	389	7	2021	2021	NUM
admet-942	389	8	)	)	PUNCT
admet-942	389	9	111	111	NUM
admet-942	389	10	-	-	SYM
admet-942	389	11	141	141	NUM
admet-942	389	12	organ	organ	NOUN
admet-942	389	13	-	-	PUNCT
admet-942	389	14	on	on	ADP
admet-942	389	15	-	-	PUNCT
admet-942	389	16	a	a	DET
admet-942	389	17	-	-	PUNCT
admet-942	389	18	chip	chip	NOUN
admet-942	389	19	systems	system	NOUN
admet-942	389	20	for	for	ADP
admet-942	389	21	new	new	ADJ
admet-942	389	22	drugs	drug	NOUN
admet-942	389	23	development	development	NOUN
admet-942	389	24	doi	doi	PROPN
admet-942	389	25	:	:	PUNCT
admet-942	389	26	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	389	27	127	127	NUM
admet-942	389	28	scientists	scientist	NOUN
admet-942	389	29	have	have	AUX
admet-942	389	30	been	be	AUX
admet-942	389	31	able	able	ADJ
admet-942	389	32	to	to	PART
admet-942	389	33	modulate	modulate	VERB
admet-942	389	34	through	through	ADP
admet-942	389	35	ooc	ooc	PROPN
admet-942	389	36	devices	device	NOUN
admet-942	389	37	phenomena	phenomenon	NOUN
admet-942	389	38	such	such	ADJ
admet-942	389	39	as	as	ADP
admet-942	389	40	metastatic	metastatic	ADJ
admet-942	389	41	cells	cell	NOUN
admet-942	389	42	migration	migration	NOUN
admet-942	389	43	,	,	PUNCT
admet-942	389	44	tumor	tumor	NOUN
admet-942	389	45	growth	growth	NOUN
admet-942	389	46	or	or	CCONJ
admet-942	389	47	even	even	ADV
admet-942	389	48	drug	drug	NOUN
admet-942	389	49	resistance	resistance	NOUN
admet-942	390	1	[	[	X
admet-942	390	2	124,132	124,132	NUM
admet-942	390	3	]	]	PUNCT
admet-942	390	4	.	.	PUNCT
admet-942	391	1	moreover	moreover	ADV
admet-942	391	2	,	,	PUNCT
admet-942	391	3	potential	potential	ADJ
admet-942	391	4	therapeutic	therapeutic	ADJ
admet-942	391	5	targets	target	NOUN
admet-942	391	6	and	and	CCONJ
admet-942	391	7	possible	possible	ADJ
admet-942	391	8	chemical	chemical	NOUN
admet-942	391	9	markers	marker	NOUN
admet-942	391	10	have	have	AUX
admet-942	391	11	been	be	AUX
admet-942	391	12	identified	identify	VERB
admet-942	391	13	in	in	ADP
admet-942	391	14	preliminary	preliminary	ADJ
admet-942	391	15	research	research	NOUN
admet-942	391	16	based	base	VERB
admet-942	391	17	on	on	ADP
admet-942	391	18	ooc	ooc	PRON
admet-942	391	19	[	[	X
admet-942	391	20	15	15	NUM
admet-942	391	21	]	]	PUNCT
admet-942	391	22	.	.	PUNCT
admet-942	392	1	nguyen	nguyen	PROPN
admet-942	392	2	et	et	PROPN
admet-942	392	3	al	al	PROPN
admet-942	392	4	.	.	PROPN
admet-942	392	5	used	use	VERB
admet-942	392	6	an	an	DET
admet-942	392	7	ooc	ooc	NOUN
admet-942	392	8	model	model	NOUN
admet-942	392	9	to	to	PART
admet-942	392	10	demonstrate	demonstrate	VERB
admet-942	392	11	pathogenic	pathogenic	ADJ
admet-942	392	12	mechanisms	mechanism	NOUN
admet-942	392	13	involved	involve	VERB
admet-942	392	14	with	with	ADP
admet-942	392	15	the	the	DET
admet-942	392	16	endothelial	endothelial	ADJ
admet-942	392	17	changes	change	NOUN
admet-942	392	18	observed	observe	VERB
admet-942	392	19	in	in	ADP
admet-942	392	20	pancreatic	pancreatic	ADJ
admet-942	392	21	cancer	cancer	NOUN
admet-942	392	22	,	,	PUNCT
admet-942	392	23	as	as	ADV
admet-942	392	24	well	well	ADV
admet-942	392	25	as	as	ADP
admet-942	392	26	to	to	PART
admet-942	392	27	identify	identify	VERB
admet-942	392	28	chemical	chemical	ADJ
admet-942	392	29	mediators	mediator	NOUN
admet-942	392	30	of	of	ADP
admet-942	392	31	these	these	DET
admet-942	392	32	phenomena	phenomenon	NOUN
admet-942	392	33	(	(	PUNCT
admet-942	392	34	figure	figure	NOUN
admet-942	392	35	11	11	NUM
admet-942	392	36	)	)	PUNCT
admet-942	393	1	[	[	X
admet-942	393	2	125	125	NUM
admet-942	393	3	]	]	PUNCT
admet-942	393	4	.	.	PUNCT
admet-942	394	1	shuford	shuford	PROPN
admet-942	394	2	et	et	PROPN
admet-942	394	3	al	al	PROPN
admet-942	394	4	.	.	PROPN
admet-942	395	1	used	use	VERB
admet-942	395	2	primary	primary	ADJ
admet-942	395	3	patient	patient	ADJ
admet-942	395	4	tissue	tissue	NOUN
admet-942	395	5	on	on	ADP
admet-942	395	6	a	a	DET
admet-942	395	7	chip	chip	NOUN
admet-942	395	8	for	for	ADP
admet-942	395	9	the	the	DET
admet-942	395	10	prediction	prediction	NOUN
admet-942	395	11	of	of	ADP
admet-942	395	12	patient	patient	NOUN
admet-942	395	13	-	-	PUNCT
admet-942	395	14	specific	specific	ADJ
admet-942	395	15	response	response	NOUN
admet-942	395	16	before	before	ADP
admet-942	395	17	clinical	clinical	ADJ
admet-942	395	18	treatment	treatment	NOUN
admet-942	395	19	in	in	ADP
admet-942	395	20	ovarian	ovarian	ADJ
admet-942	395	21	cancer	cancer	NOUN
admet-942	395	22	[	[	X
admet-942	395	23	126	126	NUM
admet-942	395	24	]	]	PUNCT
admet-942	395	25	.	.	PUNCT
admet-942	396	1	choi	choi	PROPN
admet-942	396	2	et	et	PROPN
admet-942	396	3	al	al	PROPN
admet-942	396	4	.	.	PROPN
admet-942	396	5	designed	design	VERB
admet-942	396	6	a	a	DET
admet-942	396	7	device	device	NOUN
admet-942	396	8	with	with	ADP
admet-942	396	9	the	the	DET
admet-942	396	10	microarchitecture	microarchitecture	NOUN
admet-942	396	11	of	of	ADP
admet-942	396	12	breast	breast	NOUN
admet-942	396	13	carcinoma	carcinoma	NOUN
admet-942	396	14	to	to	PART
admet-942	396	15	be	be	AUX
admet-942	396	16	used	use	VERB
admet-942	396	17	as	as	ADP
admet-942	396	18	drug	drug	NOUN
admet-942	396	19	screening	screening	NOUN
admet-942	396	20	platform	platform	NOUN
admet-942	396	21	.	.	PUNCT
admet-942	397	1	they	they	PRON
admet-942	397	2	validated	validate	VERB
admet-942	397	3	the	the	DET
admet-942	397	4	screening	screening	NOUN
admet-942	397	5	capacity	capacity	NOUN
admet-942	397	6	using	use	VERB
admet-942	397	7	it	it	PRON
admet-942	397	8	to	to	PART
admet-942	397	9	evaluate	evaluate	VERB
admet-942	397	10	efficacy	efficacy	NOUN
admet-942	397	11	and	and	CCONJ
admet-942	397	12	toxicity	toxicity	NOUN
admet-942	397	13	of	of	ADP
admet-942	397	14	paclitaxel	paclitaxel	NOUN
admet-942	397	15	[	[	X
admet-942	397	16	127	127	NUM
admet-942	397	17	]	]	PUNCT
admet-942	397	18	.	.	PUNCT
admet-942	398	1	body	body	NOUN
admet-942	398	2	-	-	PUNCT
admet-942	398	3	on	on	ADP
admet-942	398	4	-	-	PUNCT
admet-942	398	5	a	a	DET
admet-942	398	6	-	-	PUNCT
admet-942	398	7	chip	chip	NOUN
admet-942	398	8	or	or	CCONJ
admet-942	398	9	human	human	NOUN
admet-942	398	10	-	-	PUNCT
admet-942	398	11	on	on	ADP
admet-942	398	12	-	-	PUNCT
admet-942	398	13	a	a	DET
admet-942	398	14	-	-	PUNCT
admet-942	398	15	chip	chip	NOUN
admet-942	398	16	for	for	ADP
admet-942	398	17	adme	adme	NOUN
admet-942	398	18	evaluation	evaluation	NOUN
admet-942	398	19	and	and	CCONJ
admet-942	398	20	preclinical	preclinical	ADJ
admet-942	398	21	development	development	NOUN
admet-942	398	22	oocs	ooc	NOUN
admet-942	398	23	can	can	AUX
admet-942	398	24	assembly	assembly	VERB
admet-942	398	25	multiple	multiple	ADJ
admet-942	398	26	tissues	tissue	NOUN
admet-942	398	27	and	and	CCONJ
admet-942	398	28	simulate	simulate	VERB
admet-942	398	29	the	the	DET
admet-942	398	30	systematic	systematic	ADJ
admet-942	398	31	functionality	functionality	NOUN
admet-942	398	32	of	of	ADP
admet-942	398	33	the	the	DET
admet-942	398	34	human	human	ADJ
admet-942	398	35	body	body	NOUN
admet-942	398	36	.	.	PUNCT
admet-942	399	1	as	as	ADV
admet-942	399	2	long	long	ADV
admet-942	399	3	as	as	SCONJ
admet-942	399	4	each	each	DET
admet-942	399	5	organ	organ	NOUN
admet-942	399	6	shows	show	VERB
admet-942	399	7	the	the	DET
admet-942	399	8	most	most	ADV
admet-942	399	9	relevant	relevant	ADJ
admet-942	399	10	functions	function	NOUN
admet-942	399	11	associated	associate	VERB
admet-942	399	12	with	with	ADP
admet-942	399	13	the	the	DET
admet-942	399	14	pharmacokinetic	pharmacokinetic	ADJ
admet-942	399	15	phenomena	phenomenon	NOUN
admet-942	399	16	to	to	PART
admet-942	399	17	be	be	AUX
admet-942	399	18	studied	study	VERB
admet-942	399	19	,	,	PUNCT
admet-942	399	20	these	these	DET
admet-942	399	21	systems	system	NOUN
admet-942	399	22	have	have	VERB
admet-942	399	23	the	the	DET
admet-942	399	24	potential	potential	NOUN
admet-942	399	25	to	to	PART
admet-942	399	26	determine	determine	VERB
admet-942	399	27	the	the	DET
admet-942	399	28	pharmacokinetic	pharmacokinetic	ADJ
admet-942	399	29	profile	profile	NOUN
admet-942	399	30	of	of	ADP
admet-942	399	31	drugs	drug	NOUN
admet-942	399	32	[	[	X
admet-942	399	33	7,10,13,42,50,102	7,10,13,42,50,102	NOUN
admet-942	399	34	]	]	X
admet-942	399	35	.	.	PUNCT
admet-942	400	1	the	the	DET
admet-942	400	2	processes	process	NOUN
admet-942	400	3	of	of	ADP
admet-942	400	4	absorption	absorption	NOUN
admet-942	400	5	,	,	PUNCT
admet-942	400	6	distribution	distribution	NOUN
admet-942	400	7	,	,	PUNCT
admet-942	400	8	excretion	excretion	NOUN
admet-942	400	9	and	and	CCONJ
admet-942	400	10	metabolism	metabolism	NOUN
admet-942	400	11	(	(	PUNCT
admet-942	400	12	adme	adme	NOUN
admet-942	400	13	)	)	PUNCT
admet-942	400	14	can	can	AUX
admet-942	400	15	be	be	AUX
admet-942	400	16	simulated	simulate	VERB
admet-942	400	17	from	from	ADP
admet-942	400	18	various	various	ADJ
admet-942	400	19	routes	route	NOUN
admet-942	400	20	of	of	ADP
admet-942	400	21	administration	administration	NOUN
admet-942	400	22	and	and	CCONJ
admet-942	400	23	,	,	PUNCT
admet-942	400	24	moreover	moreover	ADV
admet-942	400	25	,	,	PUNCT
admet-942	400	26	mathematical	mathematical	ADJ
admet-942	400	27	models	model	NOUN
admet-942	400	28	can	can	AUX
admet-942	400	29	be	be	AUX
admet-942	400	30	applied	apply	VERB
admet-942	400	31	to	to	PART
admet-942	400	32	make	make	VERB
admet-942	400	33	real	real	ADJ
admet-942	400	34	-	-	PUNCT
admet-942	400	35	body	body	NOUN
admet-942	400	36	predictions	prediction	NOUN
admet-942	400	37	[	[	X
admet-942	400	38	10,27,51,66,132,133	10,27,51,66,132,133	NUM
admet-942	400	39	]	]	PUNCT
admet-942	400	40	.	.	PUNCT
admet-942	401	1	this	this	DET
admet-942	401	2	approach	approach	NOUN
admet-942	401	3	has	have	AUX
admet-942	401	4	been	be	AUX
admet-942	401	5	used	use	VERB
admet-942	401	6	to	to	PART
admet-942	401	7	evaluate	evaluate	VERB
admet-942	401	8	the	the	DET
admet-942	401	9	adme	adme	NOUN
admet-942	401	10	profile	profile	NOUN
admet-942	401	11	of	of	ADP
admet-942	401	12	drugs	drug	NOUN
admet-942	401	13	and	and	CCONJ
admet-942	401	14	the	the	DET
admet-942	401	15	appearance	appearance	NOUN
admet-942	401	16	of	of	ADP
admet-942	401	17	physiological	physiological	ADJ
admet-942	401	18	events	event	NOUN
admet-942	401	19	that	that	PRON
admet-942	401	20	cause	cause	VERB
admet-942	401	21	adverse	adverse	ADJ
admet-942	401	22	effects	effect	NOUN
admet-942	401	23	in	in	ADP
admet-942	401	24	devices	device	NOUN
admet-942	401	25	of	of	ADP
admet-942	401	26	up	up	ADP
admet-942	401	27	to	to	PART
admet-942	401	28	20	20	NUM
admet-942	401	29	different	different	ADJ
admet-942	401	30	tissues	tissue	NOUN
admet-942	402	1	[	[	X
admet-942	402	2	7,10,32	7,10,32	NUM
admet-942	402	3	]	]	PUNCT
admet-942	402	4	.	.	PUNCT
admet-942	403	1	furthermore	furthermore	ADV
admet-942	403	2	,	,	PUNCT
admet-942	403	3	they	they	PRON
admet-942	403	4	can	can	AUX
admet-942	403	5	also	also	ADV
admet-942	403	6	be	be	AUX
admet-942	403	7	used	use	VERB
admet-942	403	8	to	to	PART
admet-942	403	9	assess	assess	VERB
admet-942	403	10	a	a	DET
admet-942	403	11	compound	compound	NOUN
admet-942	403	12	effectiveness	effectiveness	NOUN
admet-942	403	13	[	[	X
admet-942	403	14	13,133	13,133	NUM
admet-942	403	15	]	]	PUNCT
admet-942	403	16	.	.	PUNCT
admet-942	404	1	de	de	PROPN
admet-942	404	2	melo	melo	PROPN
admet-942	404	3	et	et	PROPN
admet-942	404	4	al	al	PROPN
admet-942	404	5	.	.	PROPN
admet-942	404	6	developed	develop	VERB
admet-942	404	7	a	a	DET
admet-942	404	8	heart	heart	NOUN
admet-942	404	9	-	-	PUNCT
admet-942	404	10	liver	liver	NOUN
admet-942	404	11	-	-	PUNCT
admet-942	404	12	skin	skin	NOUN
admet-942	404	13	device	device	NOUN
admet-942	404	14	for	for	ADP
admet-942	404	15	the	the	DET
admet-942	404	16	systemic	systemic	ADJ
admet-942	404	17	evaluation	evaluation	NOUN
admet-942	404	18	of	of	ADP
admet-942	404	19	drugs	drug	NOUN
admet-942	404	20	administrated	administrate	VERB
admet-942	404	21	topically	topically	ADV
admet-942	404	22	and	and	CCONJ
admet-942	404	23	for	for	ADP
admet-942	404	24	the	the	DET
admet-942	404	25	comparison	comparison	NOUN
admet-942	404	26	of	of	ADP
admet-942	404	27	acute	acute	ADJ
admet-942	404	28	and	and	CCONJ
admet-942	404	29	systemic	systemic	ADJ
admet-942	404	30	toxicity	toxicity	NOUN
admet-942	404	31	(	(	PUNCT
admet-942	404	32	figure	figure	NOUN
admet-942	404	33	2b	2b	NOUN
admet-942	404	34	)	)	PUNCT
admet-942	405	1	[	[	X
admet-942	405	2	67	67	NUM
admet-942	405	3	]	]	PUNCT
admet-942	405	4	.	.	PUNCT
admet-942	406	1	figure	figure	NOUN
admet-942	406	2	11	11	NUM
admet-942	406	3	.	.	PUNCT
admet-942	407	1	pancreatic	pancreatic	ADJ
admet-942	407	2	-	-	PUNCT
admet-942	407	3	cancer	cancer	NOUN
admet-942	407	4	-	-	PUNCT
admet-942	407	5	on	on	ADP
admet-942	407	6	-	-	PUNCT
admet-942	407	7	a	a	DET
admet-942	407	8	-	-	PUNCT
admet-942	407	9	chip	chip	NOUN
admet-942	407	10	.	.	PUNCT
admet-942	408	1	a	a	PRON
admet-942	408	2	)	)	PUNCT
admet-942	408	3	i	i	PRON
admet-942	408	4	:	:	PUNCT
admet-942	408	5	image	image	NOUN
admet-942	408	6	of	of	ADP
admet-942	408	7	a	a	DET
admet-942	408	8	pancreatic	pancreatic	ADJ
admet-942	408	9	duct	duct	NOUN
admet-942	408	10	(	(	PUNCT
admet-942	408	11	seeded	seed	VERB
admet-942	408	12	with	with	ADP
admet-942	408	13	pancreatic	pancreatic	ADJ
admet-942	408	14	cancer	cancer	NOUN
admet-942	408	15	cells	cell	NOUN
admet-942	408	16	)	)	PUNCT
admet-942	408	17	and	and	CCONJ
admet-942	408	18	a	a	DET
admet-942	408	19	blood	blood	NOUN
admet-942	408	20	vessel	vessel	NOUN
admet-942	408	21	(	(	PUNCT
admet-942	408	22	seeded	seed	VERB
admet-942	408	23	with	with	ADP
admet-942	408	24	endothelial	endothelial	ADJ
admet-942	408	25	cells	cell	NOUN
admet-942	408	26	)	)	PUNCT
admet-942	408	27	nested	nest	VERB
admet-942	408	28	within	within	ADP
admet-942	408	29	a	a	DET
admet-942	408	30	collagen	collagen	NOUN
admet-942	408	31	matrix	matrix	NOUN
admet-942	408	32	that	that	PRON
admet-942	408	33	are	be	AUX
admet-942	408	34	shown	show	VERB
admet-942	408	35	on	on	ADP
admet-942	408	36	the	the	DET
admet-942	408	37	right	right	ADJ
admet-942	408	38	image	image	NOUN
admet-942	408	39	;	;	PUNCT
admet-942	408	40	ii	ii	NUM
admet-942	408	41	:	:	PUNCT
admet-942	408	42	representation	representation	NOUN
admet-942	408	43	of	of	ADP
admet-942	408	44	the	the	DET
admet-942	408	45	cross	cross	NOUN
admet-942	408	46	section	section	NOUN
admet-942	408	47	of	of	ADP
admet-942	408	48	the	the	DET
admet-942	408	49	right	right	ADJ
admet-942	408	50	image	image	NOUN
admet-942	408	51	.	.	PUNCT
admet-942	409	1	b	b	X
admet-942	409	2	)	)	PUNCT
admet-942	409	3	invasion	invasion	NOUN
admet-942	409	4	distance	distance	NOUN
admet-942	409	5	that	that	SCONJ
admet-942	409	6	cancer	cancer	NOUN
admet-942	409	7	cells	cell	NOUN
admet-942	409	8	traverse	traverse	VERB
admet-942	409	9	within	within	ADP
admet-942	409	10	the	the	DET
admet-942	409	11	collagen	collagen	NOUN
admet-942	409	12	matrix	matrix	NOUN
admet-942	409	13	as	as	ADP
admet-942	409	14	a	a	DET
admet-942	409	15	function	function	NOUN
admet-942	409	16	of	of	ADP
admet-942	409	17	time	time	NOUN
admet-942	409	18	,	,	PUNCT
admet-942	409	19	with	with	ADP
admet-942	409	20	and	and	CCONJ
admet-942	409	21	without	without	ADP
admet-942	409	22	the	the	DET
admet-942	409	23	addition	addition	NOUN
admet-942	409	24	of	of	ADP
admet-942	409	25	human	human	ADJ
admet-942	409	26	umbilical	umbilical	ADJ
admet-942	409	27	vein	vein	ADJ
admet-942	409	28	endothelial	endothelial	NOUN
admet-942	409	29	cells	cell	NOUN
admet-942	409	30	(	(	PUNCT
admet-942	409	31	huvecs	huvecs	PROPN
admet-942	409	32	)	)	PUNCT
admet-942	409	33	.	.	PUNCT
admet-942	410	1	c	c	X
admet-942	410	2	)	)	PUNCT
admet-942	410	3	and	and	CCONJ
admet-942	410	4	d	d	X
admet-942	410	5	)	)	PUNCT
admet-942	410	6	invasion	invasion	NOUN
admet-942	410	7	of	of	ADP
admet-942	410	8	tumoral	tumoral	ADJ
admet-942	410	9	cells	cell	NOUN
admet-942	410	10	(	(	PUNCT
admet-942	410	11	green	green	ADJ
admet-942	410	12	)	)	PUNCT
admet-942	410	13	into	into	ADP
admet-942	410	14	the	the	DET
admet-942	410	15	blood	blood	NOUN
admet-942	410	16	vessel	vessel	NOUN
admet-942	410	17	(	(	PUNCT
admet-942	410	18	red	red	ADJ
admet-942	410	19	)	)	PUNCT
admet-942	410	20	.	.	PUNCT
admet-942	411	1	e	e	X
admet-942	411	2	)	)	PUNCT
admet-942	412	1	i	i	PRON
admet-942	412	2	:	:	PUNCT
admet-942	412	3	invasion	invasion	NOUN
admet-942	412	4	of	of	ADP
admet-942	412	5	the	the	DET
admet-942	412	6	blood	blood	NOUN
admet-942	412	7	vessel	vessel	NOUN
admet-942	412	8	by	by	ADP
admet-942	412	9	cancer	cancer	NOUN
admet-942	412	10	cells	cell	NOUN
admet-942	412	11	,	,	PUNCT
admet-942	412	12	inducing	induce	VERB
admet-942	412	13	to	to	ADP
admet-942	412	14	the	the	DET
admet-942	412	15	apoptosis	apoptosis	NOUN
admet-942	412	16	(	(	PUNCT
admet-942	412	17	marked	mark	VERB
admet-942	412	18	in	in	ADP
admet-942	412	19	white	white	NOUN
admet-942	412	20	in	in	ADP
admet-942	412	21	ii	ii	PROPN
admet-942	412	22	)	)	PUNCT
admet-942	412	23	of	of	ADP
admet-942	412	24	endothelial	endothelial	ADJ
admet-942	412	25	cells	cell	NOUN
admet-942	412	26	.	.	PUNCT
admet-942	413	1	modified	modify	VERB
admet-942	413	2	from	from	ADP
admet-942	413	3	[	[	X
admet-942	413	4	125	125	NUM
admet-942	413	5	]	]	PUNCT
admet-942	413	6	under	under	ADP
admet-942	413	7	terms	term	NOUN
admet-942	413	8	of	of	ADP
admet-942	413	9	the	the	DET
admet-942	413	10	creative	creative	ADJ
admet-942	413	11	commons	common	NOUN
admet-942	413	12	attribution	attribution	NOUN
admet-942	413	13	license	license	NOUN
admet-942	413	14	.	.	PUNCT
admet-942	414	1	copyright	copyright	NOUN
admet-942	414	2	(	(	PUNCT
admet-942	414	3	2019	2019	NUM
admet-942	414	4	)	)	PUNCT
admet-942	414	5	.	.	PUNCT
admet-942	415	1	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	415	2	r.	r.	PROPN
admet-942	415	3	vargas	vargas	PROPN
admet-942	415	4	,	,	PUNCT
admet-942	415	5	a.	a.	NOUN
admet-942	415	6	egurbide	egurbide	NOUN
admet-942	415	7	-	-	PUNCT
admet-942	415	8	sifre	sifre	NOUN
admet-942	415	9	and	and	CCONJ
admet-942	415	10	l.	l.	PROPN
admet-942	415	11	medina	medina	PROPN
admet-942	415	12	admet	admet	PROPN
admet-942	415	13	&	&	CCONJ
admet-942	415	14	dmpk	dmpk	PROPN
admet-942	415	15	9(2	9(2	NUM
admet-942	415	16	)	)	PUNCT
admet-942	415	17	(	(	PUNCT
admet-942	415	18	2021	2021	NUM
admet-942	415	19	)	)	PUNCT
admet-942	415	20	111	111	NUM
admet-942	415	21	-	-	SYM
admet-942	415	22	141	141	NUM
admet-942	415	23	128	128	NUM
admet-942	415	24	the	the	DET
admet-942	415	25	system	system	NOUN
admet-942	415	26	developed	develop	VERB
admet-942	415	27	by	by	ADP
admet-942	415	28	rajan	rajan	PROPN
admet-942	415	29	et	et	PROPN
admet-942	415	30	al	al	PROPN
admet-942	415	31	.	.	PROPN
admet-942	415	32	including	include	VERB
admet-942	415	33	tissues	tissue	NOUN
admet-942	415	34	from	from	ADP
admet-942	415	35	the	the	DET
admet-942	415	36	brain	brain	NOUN
admet-942	415	37	,	,	PUNCT
admet-942	415	38	liver	liver	NOUN
admet-942	415	39	,	,	PUNCT
admet-942	415	40	lung	lung	NOUN
admet-942	415	41	,	,	PUNCT
admet-942	415	42	heart	heart	NOUN
admet-942	415	43	and	and	CCONJ
admet-942	415	44	endothelium	endothelium	NOUN
admet-942	415	45	showed	show	VERB
admet-942	415	46	metabolizing	metabolize	VERB
admet-942	415	47	capacity	capacity	NOUN
admet-942	415	48	for	for	ADP
admet-942	415	49	prodrug	prodrug	NOUN
admet-942	415	50	transformation	transformation	NOUN
admet-942	415	51	,	,	PUNCT
admet-942	415	52	as	as	ADV
admet-942	415	53	well	well	ADV
admet-942	415	54	as	as	ADP
admet-942	415	55	representativity	representativity	NOUN
admet-942	415	56	of	of	ADP
admet-942	415	57	cardiac	cardiac	ADJ
admet-942	415	58	toxicity	toxicity	NOUN
admet-942	415	59	[	[	X
admet-942	415	60	10	10	NUM
admet-942	415	61	]	]	PUNCT
admet-942	415	62	.	.	PUNCT
admet-942	416	1	marin	marin	NOUN
admet-942	416	2	et	et	PROPN
admet-942	416	3	al	al	PROPN
admet-942	416	4	.	.	PROPN
admet-942	416	5	studied	study	VERB
admet-942	416	6	acetaminophen	acetaminophen	NOUN
admet-942	416	7	absorption	absorption	NOUN
admet-942	416	8	and	and	CCONJ
admet-942	416	9	metabolism	metabolism	NOUN
admet-942	416	10	with	with	ADP
admet-942	416	11	an	an	DET
admet-942	416	12	intestine	intestine	NOUN
admet-942	416	13	/	/	SYM
admet-942	416	14	liver	liver	NOUN
admet-942	416	15	microphysiological	microphysiological	ADJ
admet-942	416	16	system	system	NOUN
admet-942	416	17	demonstrating	demonstrate	VERB
admet-942	416	18	the	the	DET
admet-942	416	19	potential	potential	NOUN
admet-942	416	20	of	of	ADP
admet-942	416	21	these	these	DET
admet-942	416	22	kind	kind	NOUN
admet-942	416	23	of	of	ADP
admet-942	416	24	systems	system	NOUN
admet-942	416	25	for	for	ADP
admet-942	416	26	pharmacokinetic	pharmacokinetic	ADJ
admet-942	416	27	profiling	profiling	NOUN
admet-942	416	28	of	of	ADP
admet-942	416	29	drug	drug	NOUN
admet-942	416	30	substances	substance	NOUN
admet-942	416	31	[	[	X
admet-942	416	32	51	51	NUM
admet-942	416	33	]	]	PUNCT
admet-942	416	34	.	.	PUNCT
admet-942	417	1	the	the	DET
admet-942	417	2	cardiotoxicity	cardiotoxicity	NOUN
admet-942	417	3	of	of	ADP
admet-942	417	4	the	the	DET
admet-942	417	5	main	main	ADJ
admet-942	417	6	compound	compound	NOUN
admet-942	417	7	and	and	CCONJ
admet-942	417	8	the	the	DET
admet-942	417	9	metabolites	metabolite	NOUN
admet-942	417	10	was	be	AUX
admet-942	417	11	evaluated	evaluate	VERB
admet-942	417	12	with	with	ADP
admet-942	417	13	an	an	DET
admet-942	417	14	ooc	ooc	ADJ
admet-942	417	15	device	device	NOUN
admet-942	417	16	by	by	ADP
admet-942	417	17	oleaga	oleaga	NOUN
admet-942	417	18	et	et	PROPN
admet-942	417	19	al	al	PROPN
admet-942	417	20	.	.	PROPN
admet-942	417	21	,	,	PUNCT
admet-942	417	22	who	who	PRON
admet-942	417	23	developed	develop	VERB
admet-942	417	24	a	a	DET
admet-942	417	25	model	model	NOUN
admet-942	417	26	that	that	PRON
admet-942	417	27	can	can	AUX
admet-942	417	28	be	be	AUX
admet-942	417	29	used	use	VERB
admet-942	417	30	in	in	ADP
admet-942	417	31	preclinical	preclinical	ADJ
admet-942	417	32	evaluation	evaluation	NOUN
admet-942	417	33	and	and	CCONJ
admet-942	417	34	for	for	ADP
admet-942	417	35	chronic	chronic	ADJ
admet-942	417	36	studies	study	NOUN
admet-942	417	37	[	[	X
admet-942	417	38	11	11	NUM
admet-942	417	39	]	]	PUNCT
admet-942	417	40	.	.	PUNCT
admet-942	418	1	maschmeyer	maschmeyer	PROPN
admet-942	418	2	et	et	PROPN
admet-942	418	3	al	al	PROPN
admet-942	418	4	.	.	PROPN
admet-942	418	5	proposed	propose	VERB
admet-942	418	6	one	one	NUM
admet-942	418	7	of	of	ADP
admet-942	418	8	the	the	DET
admet-942	418	9	first	first	ADJ
admet-942	418	10	devices	device	NOUN
admet-942	418	11	to	to	PART
admet-942	418	12	integrate	integrate	VERB
admet-942	418	13	intestine	intestine	NOUN
admet-942	418	14	,	,	PUNCT
admet-942	418	15	liver	liver	NOUN
admet-942	418	16	,	,	PUNCT
admet-942	418	17	skin	skin	NOUN
admet-942	418	18	and	and	CCONJ
admet-942	418	19	kidney	kidney	NOUN
admet-942	418	20	organoids	organoid	NOUN
admet-942	418	21	for	for	ADP
admet-942	418	22	adme	adme	NOUN
admet-942	418	23	profiling	profiling	NOUN
admet-942	418	24	,	,	PUNCT
admet-942	418	25	and	and	CCONJ
admet-942	418	26	repeated	repeat	VERB
admet-942	418	27	dose	dose	NOUN
admet-942	418	28	systemic	systemic	ADJ
admet-942	418	29	toxicity	toxicity	NOUN
admet-942	418	30	testing	testing	NOUN
admet-942	418	31	of	of	ADP
admet-942	418	32	drug	drug	NOUN
admet-942	418	33	candidates	candidate	NOUN
admet-942	418	34	,	,	PUNCT
admet-942	418	35	which	which	PRON
admet-942	418	36	was	be	AUX
admet-942	418	37	sustainable	sustainable	ADJ
admet-942	418	38	throughout	throughout	ADP
admet-942	418	39	28	28	NUM
admet-942	418	40	days	day	NOUN
admet-942	418	41	[	[	X
admet-942	418	42	134	134	NUM
admet-942	418	43	]	]	PUNCT
admet-942	418	44	.	.	PUNCT
admet-942	419	1	the	the	DET
admet-942	419	2	system	system	NOUN
admet-942	419	3	of	of	ADP
admet-942	419	4	fluidically	fluidically	ADV
admet-942	419	5	coupled	couple	VERB
admet-942	419	6	vascularized	vascularized	ADJ
admet-942	419	7	chips	chip	NOUN
admet-942	419	8	proposed	propose	VERB
admet-942	419	9	by	by	ADP
admet-942	419	10	herland	herland	PROPN
admet-942	419	11	et	et	PROPN
admet-942	419	12	al	al	PROPN
admet-942	419	13	.	.	PROPN
admet-942	419	14	allowed	allow	VERB
admet-942	419	15	modeling	model	VERB
admet-942	419	16	the	the	DET
admet-942	419	17	pharmacokinetics	pharmacokinetic	NOUN
admet-942	419	18	of	of	ADP
admet-942	419	19	orally	orally	ADV
admet-942	419	20	and	and	CCONJ
admet-942	419	21	intravenous	intravenous	ADJ
admet-942	419	22	administered	administer	VERB
admet-942	419	23	drugs	drug	NOUN
admet-942	419	24	.	.	PUNCT
admet-942	420	1	their	their	PRON
admet-942	420	2	arrangement	arrangement	NOUN
admet-942	420	3	was	be	AUX
admet-942	420	4	able	able	ADJ
admet-942	420	5	to	to	PART
admet-942	420	6	couple	couple	VERB
admet-942	420	7	with	with	ADP
admet-942	420	8	robotic	robotic	ADJ
admet-942	420	9	pumps	pump	NOUN
admet-942	420	10	,	,	PUNCT
admet-942	420	11	chips	chip	NOUN
admet-942	420	12	that	that	PRON
admet-942	420	13	represent	represent	VERB
admet-942	420	14	the	the	DET
admet-942	420	15	gut	gut	NOUN
admet-942	420	16	,	,	PUNCT
admet-942	420	17	liver	liver	NOUN
admet-942	420	18	,	,	PUNCT
admet-942	420	19	kidney	kidney	NOUN
admet-942	420	20	,	,	PUNCT
admet-942	420	21	and	and	CCONJ
admet-942	420	22	bone	bone	NOUN
admet-942	420	23	marrow	marrow	NOUN
admet-942	420	24	,	,	PUNCT
admet-942	420	25	and	and	CCONJ
admet-942	420	26	presented	present	VERB
admet-942	420	27	an	an	DET
admet-942	420	28	arteriovenous	arteriovenous	ADJ
admet-942	420	29	fluid	fluid	NOUN
admet-942	420	30	-	-	PUNCT
admet-942	420	31	mixing	mix	VERB
admet-942	420	32	reservoir	reservoir	NOUN
admet-942	420	33	.	.	PUNCT
admet-942	421	1	they	they	PRON
admet-942	421	2	obtained	obtain	VERB
admet-942	421	3	pharmacokinetic	pharmacokinetic	ADJ
admet-942	421	4	results	result	NOUN
admet-942	421	5	similar	similar	ADJ
admet-942	421	6	to	to	AUX
admet-942	421	7	previously	previously	ADV
admet-942	421	8	reported	report	VERB
admet-942	421	9	clinical	clinical	ADJ
admet-942	421	10	data	datum	NOUN
admet-942	421	11	[	[	X
admet-942	421	12	135	135	NUM
admet-942	421	13	]	]	PUNCT
admet-942	421	14	.	.	PUNCT
admet-942	422	1	one	one	NUM
admet-942	422	2	of	of	ADP
admet-942	422	3	the	the	DET
admet-942	422	4	most	most	ADV
admet-942	422	5	important	important	ADJ
admet-942	422	6	challenges	challenge	NOUN
admet-942	422	7	in	in	ADP
admet-942	422	8	the	the	DET
admet-942	422	9	body	body	NOUN
admet-942	422	10	-	-	PUNCT
admet-942	422	11	on	on	ADP
admet-942	422	12	-	-	PUNCT
admet-942	422	13	a	a	DET
admet-942	422	14	-	-	PUNCT
admet-942	422	15	chip	chip	NOUN
admet-942	422	16	development	development	NOUN
admet-942	422	17	is	be	AUX
admet-942	422	18	the	the	DET
admet-942	422	19	proportional	proportional	ADJ
admet-942	422	20	replication	replication	NOUN
admet-942	422	21	of	of	ADP
admet-942	422	22	organs	organ	NOUN
admet-942	422	23	in	in	ADP
admet-942	422	24	terms	term	NOUN
admet-942	422	25	of	of	ADP
admet-942	422	26	size	size	NOUN
admet-942	422	27	,	,	PUNCT
admet-942	422	28	blood	blood	NOUN
admet-942	422	29	flow	flow	NOUN
admet-942	422	30	and	and	CCONJ
admet-942	422	31	metabolic	metabolic	NOUN
admet-942	422	32	rates	rate	NOUN
admet-942	422	33	.	.	PUNCT
admet-942	423	1	however	however	ADV
admet-942	423	2	,	,	PUNCT
admet-942	423	3	in	in	ADP
admet-942	423	4	many	many	ADJ
admet-942	423	5	cases	case	NOUN
admet-942	423	6	,	,	PUNCT
admet-942	423	7	these	these	DET
admet-942	423	8	proportions	proportion	NOUN
admet-942	423	9	are	be	AUX
admet-942	423	10	still	still	ADV
admet-942	423	11	unknown	unknown	ADJ
admet-942	423	12	for	for	ADP
admet-942	423	13	the	the	DET
admet-942	423	14	human	human	ADJ
admet-942	423	15	body	body	NOUN
admet-942	423	16	[	[	X
admet-942	423	17	7	7	NUM
admet-942	423	18	]	]	PUNCT
admet-942	423	19	.	.	PUNCT
admet-942	424	1	another	another	DET
admet-942	424	2	challenge	challenge	NOUN
admet-942	424	3	of	of	ADP
admet-942	424	4	these	these	DET
admet-942	424	5	ooc	ooc	NOUN
admet-942	424	6	devices	device	NOUN
admet-942	424	7	is	be	AUX
admet-942	424	8	that	that	SCONJ
admet-942	424	9	they	they	PRON
admet-942	424	10	represent	represent	VERB
admet-942	424	11	a	a	DET
admet-942	424	12	small	small	ADJ
admet-942	424	13	number	number	NOUN
admet-942	424	14	of	of	ADP
admet-942	424	15	cells	cell	NOUN
admet-942	424	16	,	,	PUNCT
admet-942	424	17	and	and	CCONJ
admet-942	424	18	their	their	PRON
admet-942	424	19	intercommunication	intercommunication	NOUN
admet-942	424	20	substances	substance	NOUN
admet-942	424	21	undergo	undergo	VERB
admet-942	424	22	under	under	ADP
admet-942	424	23	significant	significant	ADJ
admet-942	424	24	dilution	dilution	NOUN
admet-942	424	25	conditions	condition	NOUN
admet-942	424	26	[	[	X
admet-942	424	27	42	42	NUM
admet-942	424	28	]	]	PUNCT
admet-942	424	29	.	.	PUNCT
admet-942	425	1	nearly	nearly	ADV
admet-942	425	2	a	a	DET
admet-942	425	3	70	70	NUM
admet-942	425	4	%	%	NOUN
admet-942	425	5	of	of	ADP
admet-942	425	6	drug	drug	NOUN
admet-942	425	7	withdrawals	withdrawal	NOUN
admet-942	425	8	correspond	correspond	VERB
admet-942	425	9	to	to	ADP
admet-942	425	10	hepato	hepato	NOUN
admet-942	425	11	-	-	PUNCT
admet-942	425	12	cardio	cardio	NOUN
admet-942	425	13	toxicity	toxicity	NOUN
admet-942	425	14	,	,	PUNCT
admet-942	425	15	therefore	therefore	ADV
admet-942	425	16	,	,	PUNCT
admet-942	425	17	it	it	PRON
admet-942	425	18	is	be	AUX
admet-942	425	19	believed	believe	VERB
admet-942	425	20	that	that	SCONJ
admet-942	425	21	a	a	DET
admet-942	425	22	system	system	NOUN
admet-942	425	23	that	that	PRON
admet-942	425	24	included	include	VERB
admet-942	425	25	at	at	ADP
admet-942	425	26	least	least	ADJ
admet-942	425	27	those	those	DET
admet-942	425	28	organs	organ	NOUN
admet-942	425	29	would	would	AUX
admet-942	425	30	be	be	AUX
admet-942	425	31	enough	enough	ADJ
admet-942	425	32	for	for	SCONJ
admet-942	425	33	a	a	DET
admet-942	425	34	preclinical	preclinical	ADJ
admet-942	425	35	safety	safety	NOUN
admet-942	425	36	screening	screen	VERB
admet-942	425	37	[	[	X
admet-942	425	38	136	136	NUM
admet-942	425	39	]	]	PUNCT
admet-942	425	40	.	.	PUNCT
admet-942	426	1	oocs	ooc	NOUN
admet-942	426	2	could	could	AUX
admet-942	426	3	be	be	AUX
admet-942	426	4	used	use	VERB
admet-942	426	5	in	in	ADP
admet-942	426	6	the	the	DET
admet-942	426	7	future	future	NOUN
admet-942	426	8	for	for	ADP
admet-942	426	9	clinical	clinical	ADJ
admet-942	426	10	studies	study	NOUN
admet-942	426	11	by	by	ADP
admet-942	426	12	introducing	introduce	VERB
admet-942	426	13	specific	specific	ADJ
admet-942	426	14	variables	variable	NOUN
admet-942	426	15	needed	need	VERB
admet-942	426	16	according	accord	VERB
admet-942	426	17	to	to	ADP
admet-942	426	18	personalized	personalized	ADJ
admet-942	426	19	groups	group	NOUN
admet-942	426	20	of	of	ADP
admet-942	426	21	patients	patient	NOUN
admet-942	426	22	.	.	PUNCT
admet-942	427	1	moreover	moreover	ADV
admet-942	427	2	,	,	PUNCT
admet-942	427	3	this	this	PRON
admet-942	427	4	might	might	AUX
admet-942	427	5	allow	allow	VERB
admet-942	427	6	studies	study	NOUN
admet-942	427	7	of	of	ADP
admet-942	427	8	pathologies	pathology	NOUN
admet-942	427	9	for	for	ADP
admet-942	427	10	which	which	PRON
admet-942	427	11	there	there	PRON
admet-942	427	12	are	be	VERB
admet-942	427	13	usually	usually	ADV
admet-942	427	14	not	not	PART
admet-942	427	15	enough	enough	ADJ
admet-942	427	16	candidates	candidate	NOUN
admet-942	427	17	for	for	ADP
admet-942	427	18	a	a	DET
admet-942	427	19	representative	representative	ADJ
admet-942	427	20	clinical	clinical	ADJ
admet-942	427	21	trial	trial	NOUN
admet-942	427	22	[	[	X
admet-942	427	23	13	13	NUM
admet-942	427	24	]	]	PUNCT
admet-942	427	25	.	.	PUNCT
admet-942	428	1	the	the	DET
admet-942	428	2	use	use	NOUN
admet-942	428	3	of	of	ADP
admet-942	428	4	ooc	ooc	NOUN
admet-942	428	5	systems	system	NOUN
admet-942	428	6	in	in	ADP
admet-942	428	7	the	the	DET
admet-942	428	8	development	development	NOUN
admet-942	428	9	of	of	ADP
admet-942	428	10	new	new	ADJ
admet-942	428	11	drugs	drug	NOUN
admet-942	428	12	would	would	AUX
admet-942	428	13	enable	enable	VERB
admet-942	428	14	designs	design	NOUN
admet-942	428	15	based	base	VERB
admet-942	428	16	on	on	ADP
admet-942	428	17	better	well	ADJ
admet-942	428	18	physiological	physiological	ADJ
admet-942	428	19	understanding	understanding	NOUN
admet-942	428	20	and	and	CCONJ
admet-942	428	21	better	well	ADJ
admet-942	428	22	candidate	candidate	NOUN
admet-942	428	23	screening	screen	VERB
admet-942	429	1	[	[	X
admet-942	429	2	86	86	NUM
admet-942	429	3	]	]	PUNCT
admet-942	429	4	.	.	PUNCT
admet-942	430	1	this	this	PRON
admet-942	430	2	would	would	AUX
admet-942	430	3	lead	lead	VERB
admet-942	430	4	to	to	ADP
admet-942	430	5	an	an	DET
admet-942	430	6	increase	increase	NOUN
admet-942	430	7	in	in	ADP
admet-942	430	8	drug	drug	NOUN
admet-942	430	9	development	development	NOUN
admet-942	430	10	efficiency	efficiency	NOUN
admet-942	430	11	by	by	ADP
admet-942	430	12	reducing	reduce	VERB
admet-942	430	13	costs	cost	NOUN
admet-942	430	14	(	(	PUNCT
admet-942	430	15	up	up	ADP
admet-942	430	16	to	to	PART
admet-942	430	17	25	25	NUM
admet-942	430	18	%	%	NOUN
admet-942	430	19	)	)	PUNCT
admet-942	430	20	and	and	CCONJ
admet-942	430	21	time	time	NOUN
admet-942	430	22	for	for	ADP
admet-942	430	23	the	the	DET
admet-942	430	24	experimental	experimental	ADJ
admet-942	430	25	phases	phase	NOUN
admet-942	430	26	[	[	X
admet-942	430	27	9,18,29	9,18,29	NUM
admet-942	430	28	]	]	PUNCT
admet-942	430	29	,	,	PUNCT
admet-942	430	30	lowering	lower	VERB
admet-942	430	31	the	the	DET
admet-942	430	32	risk	risk	NOUN
admet-942	430	33	for	for	ADP
admet-942	430	34	patients	patient	NOUN
admet-942	430	35	and	and	CCONJ
admet-942	430	36	raising	raise	VERB
admet-942	430	37	the	the	DET
admet-942	430	38	investment	investment	NOUN
admet-942	430	39	in	in	ADP
admet-942	430	40	new	new	ADJ
admet-942	430	41	drugs	drug	NOUN
admet-942	430	42	production	production	NOUN
admet-942	430	43	[	[	X
admet-942	430	44	13	13	NUM
admet-942	430	45	]	]	PUNCT
admet-942	430	46	.	.	PUNCT
admet-942	431	1	this	this	PRON
admet-942	431	2	could	could	AUX
admet-942	431	3	increase	increase	VERB
admet-942	431	4	the	the	DET
admet-942	431	5	number	number	NOUN
admet-942	431	6	of	of	ADP
admet-942	431	7	new	new	ADJ
admet-942	431	8	discoveries	discovery	NOUN
admet-942	431	9	and	and	CCONJ
admet-942	431	10	reduce	reduce	VERB
admet-942	431	11	their	their	PRON
admet-942	431	12	prices	price	NOUN
admet-942	431	13	,	,	PUNCT
admet-942	431	14	benefiting	benefit	VERB
admet-942	431	15	,	,	PUNCT
admet-942	431	16	therefore	therefore	ADV
admet-942	431	17	,	,	PUNCT
admet-942	431	18	the	the	DET
admet-942	431	19	health	health	NOUN
admet-942	431	20	systems	system	NOUN
admet-942	431	21	at	at	ADP
admet-942	431	22	various	various	ADJ
admet-942	431	23	levels	level	NOUN
admet-942	431	24	[	[	X
admet-942	431	25	9,18,20,71	9,18,20,71	X
admet-942	431	26	]	]	PUNCT
admet-942	431	27	.	.	PUNCT
admet-942	432	1	challenges	challenge	NOUN
admet-942	432	2	and	and	CCONJ
admet-942	432	3	perspectives	perspective	NOUN
admet-942	432	4	in	in	ADP
admet-942	432	5	order	order	NOUN
admet-942	432	6	to	to	PART
admet-942	432	7	exploit	exploit	VERB
admet-942	432	8	the	the	DET
admet-942	432	9	full	full	ADJ
admet-942	432	10	potential	potential	NOUN
admet-942	432	11	of	of	ADP
admet-942	432	12	ooc	ooc	NOUN
admet-942	432	13	systems	system	NOUN
admet-942	432	14	and	and	CCONJ
admet-942	432	15	make	make	VERB
admet-942	432	16	them	they	PRON
admet-942	432	17	become	become	VERB
admet-942	432	18	a	a	DET
admet-942	432	19	validated	validated	ADJ
admet-942	432	20	alternative	alternative	NOUN
admet-942	432	21	,	,	PUNCT
admet-942	432	22	several	several	ADJ
admet-942	432	23	physical	physical	ADJ
admet-942	432	24	,	,	PUNCT
admet-942	432	25	physiological	physiological	ADJ
admet-942	432	26	and	and	CCONJ
admet-942	432	27	regulatory	regulatory	ADJ
admet-942	432	28	challenges	challenge	NOUN
admet-942	432	29	must	must	AUX
admet-942	432	30	be	be	AUX
admet-942	432	31	overcome	overcome	VERB
admet-942	432	32	.	.	PUNCT
admet-942	433	1	the	the	DET
admet-942	433	2	first	first	ADJ
admet-942	433	3	step	step	NOUN
admet-942	433	4	to	to	PART
admet-942	433	5	obtain	obtain	VERB
admet-942	433	6	sophisticated	sophisticated	ADJ
admet-942	433	7	and	and	CCONJ
admet-942	433	8	accurate	accurate	ADJ
admet-942	433	9	ooc	ooc	NOUN
admet-942	433	10	with	with	ADP
admet-942	433	11	a	a	DET
admet-942	433	12	minimum	minimum	ADJ
admet-942	433	13	functional	functional	ADJ
admet-942	433	14	unit	unit	NOUN
admet-942	433	15	[	[	X
admet-942	433	16	13,133	13,133	NUM
admet-942	433	17	]	]	PUNCT
admet-942	433	18	is	be	AUX
admet-942	433	19	to	to	PART
admet-942	433	20	have	have	VERB
admet-942	433	21	a	a	DET
admet-942	433	22	deep	deep	ADJ
admet-942	433	23	knowledge	knowledge	NOUN
admet-942	433	24	of	of	ADP
admet-942	433	25	the	the	DET
admet-942	433	26	organ	organ	NOUN
admet-942	433	27	’s	’s	PART
admet-942	433	28	physiology	physiology	NOUN
admet-942	433	29	,	,	PUNCT
admet-942	433	30	the	the	DET
admet-942	433	31	cellular	cellular	ADJ
admet-942	433	32	metabolism	metabolism	NOUN
admet-942	433	33	and	and	CCONJ
admet-942	433	34	all	all	DET
admet-942	433	35	pathological	pathological	ADJ
admet-942	433	36	mechanisms	mechanism	NOUN
admet-942	433	37	that	that	PRON
admet-942	433	38	can	can	AUX
admet-942	433	39	affect	affect	VERB
admet-942	433	40	the	the	DET
admet-942	433	41	organ	organ	NOUN
admet-942	434	1	[	[	X
admet-942	434	2	31,44,50,53	31,44,50,53	NUM
admet-942	434	3	]	]	PUNCT
admet-942	434	4	.	.	PUNCT
admet-942	435	1	table	table	NOUN
admet-942	435	2	5	5	NUM
admet-942	435	3	shows	show	VERB
admet-942	435	4	the	the	DET
admet-942	435	5	main	main	ADJ
admet-942	435	6	challenges	challenge	NOUN
admet-942	435	7	or	or	CCONJ
admet-942	435	8	advances	advance	NOUN
admet-942	435	9	required	require	VERB
admet-942	435	10	in	in	ADP
admet-942	435	11	the	the	DET
admet-942	435	12	manufacture	manufacture	NOUN
admet-942	435	13	of	of	ADP
admet-942	435	14	ooc	ooc	NOUN
admet-942	435	15	systems	system	NOUN
admet-942	435	16	for	for	ADP
admet-942	435	17	some	some	DET
admet-942	435	18	specific	specific	ADJ
admet-942	435	19	organs	organ	NOUN
admet-942	435	20	.	.	PUNCT
admet-942	435	21	table	table	NOUN
admet-942	435	22	5	5	NUM
admet-942	435	23	.	.	PUNCT
admet-942	435	24	main	main	ADJ
admet-942	435	25	challenges	challenge	NOUN
admet-942	435	26	for	for	ADP
admet-942	435	27	the	the	DET
admet-942	435	28	improvement	improvement	NOUN
admet-942	435	29	of	of	ADP
admet-942	435	30	some	some	DET
admet-942	435	31	specific	specific	ADJ
admet-942	435	32	organ	organ	NOUN
admet-942	435	33	-	-	PUNCT
admet-942	435	34	on	on	ADP
admet-942	435	35	-	-	PUNCT
admet-942	435	36	a	a	DET
admet-942	435	37	-	-	PUNCT
admet-942	435	38	chip	chip	NOUN
admet-942	435	39	systems	system	NOUN
admet-942	435	40	:	:	PUNCT
admet-942	435	41	modified	modify	VERB
admet-942	435	42	from	from	ADP
admet-942	435	43	[	[	X
admet-942	435	44	1,7	1,7	NUM
admet-942	435	45	]	]	PUNCT
admet-942	435	46	.	.	PUNCT
admet-942	436	1	organ	organ	VERB
admet-942	436	2	main	main	ADJ
admet-942	436	3	challenges	challenge	NOUN
admet-942	436	4	kidney	kidney	NOUN
admet-942	436	5	formation	formation	NOUN
admet-942	436	6	of	of	ADP
admet-942	436	7	glomeruli	glomeruli	NOUN
admet-942	436	8	with	with	ADP
admet-942	436	9	podocytes	podocyte	NOUN
admet-942	436	10	and	and	CCONJ
admet-942	436	11	entangled	entangle	VERB
admet-942	436	12	proximal	proximal	ADJ
admet-942	436	13	tubules	tubule	NOUN
admet-942	436	14	.	.	PUNCT
admet-942	437	1	lung	lung	NOUN
admet-942	437	2	generation	generation	NOUN
admet-942	437	3	of	of	ADP
admet-942	437	4	biomechanical	biomechanical	ADJ
admet-942	437	5	ventilation	ventilation	NOUN
admet-942	437	6	without	without	ADP
admet-942	437	7	assistance	assistance	NOUN
admet-942	437	8	.	.	PUNCT
admet-942	438	1	further	further	ADJ
admet-942	438	2	studies	study	NOUN
admet-942	438	3	with	with	ADP
admet-942	438	4	inflammatory	inflammatory	ADJ
admet-942	438	5	and	and	CCONJ
admet-942	438	6	immunological	immunological	ADJ
admet-942	438	7	processes	process	NOUN
admet-942	438	8	and	and	CCONJ
admet-942	438	9	tumors	tumor	NOUN
admet-942	438	10	.	.	PUNCT
admet-942	439	1	heart	heart	NOUN
admet-942	439	2	establishment	establishment	NOUN
admet-942	439	3	of	of	ADP
admet-942	439	4	validated	validate	VERB
admet-942	439	5	studies	study	NOUN
admet-942	439	6	for	for	ADP
admet-942	439	7	reproducible	reproducible	ADJ
admet-942	439	8	cardiotoxicity	cardiotoxicity	NOUN
admet-942	439	9	with	with	ADP
admet-942	439	10	various	various	ADJ
admet-942	439	11	drugs	drug	NOUN
admet-942	439	12	.	.	PUNCT
admet-942	440	1	gut	gut	VERB
admet-942	440	2	deepening	deepen	VERB
admet-942	440	3	knowledge	knowledge	NOUN
admet-942	440	4	of	of	ADP
admet-942	440	5	mesenchymal	mesenchymal	ADJ
admet-942	440	6	-	-	ADJ
admet-942	440	7	epithelial	epithelial	ADJ
admet-942	440	8	interactions	interaction	NOUN
admet-942	440	9	.	.	PUNCT
admet-942	441	1	placenta	placenta	NOUN
admet-942	441	2	modelling	modelling	NOUN
admet-942	441	3	with	with	ADP
admet-942	441	4	primary	primary	ADJ
admet-942	441	5	cells	cell	NOUN
admet-942	441	6	.	.	PUNCT
admet-942	442	1	adipose	adipose	ADP
admet-942	442	2	tissue	tissue	NOUN
admet-942	442	3	more	more	ADJ
admet-942	442	4	knowledge	knowledge	NOUN
admet-942	442	5	of	of	ADP
admet-942	442	6	the	the	DET
admet-942	442	7	functioning	functioning	NOUN
admet-942	442	8	of	of	ADP
admet-942	442	9	brown	brown	ADJ
admet-942	442	10	fat	fat	NOUN
admet-942	442	11	in	in	ADP
admet-942	442	12	adipose	adipose	ADJ
admet-942	442	13	tissue	tissue	NOUN
admet-942	442	14	.	.	PUNCT
admet-942	443	1	brain	brain	NOUN
admet-942	443	2	standardization	standardization	NOUN
admet-942	443	3	and	and	CCONJ
admet-942	443	4	reproducibility	reproducibility	NOUN
admet-942	443	5	of	of	ADP
admet-942	443	6	brain	brain	NOUN
admet-942	443	7	organoids	organoid	NOUN
admet-942	443	8	.	.	PUNCT
admet-942	444	1	admet	admet	PROPN
admet-942	444	2	&	&	CCONJ
admet-942	444	3	dmpk	dmpk	PROPN
admet-942	444	4	9(2	9(2	NUM
admet-942	444	5	)	)	PUNCT
admet-942	444	6	(	(	PUNCT
admet-942	444	7	2021	2021	NUM
admet-942	444	8	)	)	PUNCT
admet-942	444	9	111	111	NUM
admet-942	444	10	-	-	SYM
admet-942	444	11	141	141	NUM
admet-942	444	12	organ	organ	NOUN
admet-942	444	13	-	-	PUNCT
admet-942	444	14	on	on	ADP
admet-942	444	15	-	-	PUNCT
admet-942	444	16	a	a	DET
admet-942	444	17	-	-	PUNCT
admet-942	444	18	chip	chip	NOUN
admet-942	444	19	systems	system	NOUN
admet-942	444	20	for	for	ADP
admet-942	444	21	new	new	ADJ
admet-942	444	22	drugs	drug	NOUN
admet-942	444	23	development	development	NOUN
admet-942	444	24	doi	doi	PROPN
admet-942	444	25	:	:	PUNCT
admet-942	444	26	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	NOUN
admet-942	444	27	129	129	NUM
admet-942	444	28	as	as	ADP
admet-942	444	29	a	a	DET
admet-942	444	30	field	field	NOUN
admet-942	444	31	that	that	PRON
admet-942	444	32	influences	influence	VERB
admet-942	444	33	a	a	DET
admet-942	444	34	wide	wide	ADJ
admet-942	444	35	spectrum	spectrum	NOUN
admet-942	444	36	of	of	ADP
admet-942	444	37	disciplines	discipline	NOUN
admet-942	444	38	[	[	X
admet-942	444	39	22	22	NUM
admet-942	444	40	]	]	PUNCT
admet-942	444	41	,	,	PUNCT
admet-942	444	42	oocs	ooc	NOUN
admet-942	444	43	require	require	VERB
admet-942	444	44	significant	significant	ADJ
admet-942	444	45	advances	advance	NOUN
admet-942	444	46	in	in	ADP
admet-942	444	47	the	the	DET
admet-942	444	48	availability	availability	NOUN
admet-942	444	49	and	and	CCONJ
admet-942	444	50	the	the	DET
admet-942	444	51	implementation	implementation	NOUN
admet-942	444	52	of	of	ADP
admet-942	444	53	the	the	DET
admet-942	444	54	newest	new	ADJ
admet-942	444	55	trends	trend	NOUN
admet-942	444	56	from	from	ADP
admet-942	444	57	the	the	DET
admet-942	444	58	scientific	scientific	ADJ
admet-942	444	59	areas	area	NOUN
admet-942	444	60	related	relate	VERB
admet-942	444	61	to	to	ADP
admet-942	444	62	their	their	PRON
admet-942	444	63	design	design	NOUN
admet-942	444	64	,	,	PUNCT
admet-942	444	65	development	development	NOUN
admet-942	444	66	,	,	PUNCT
admet-942	444	67	application	application	NOUN
admet-942	444	68	and	and	CCONJ
admet-942	444	69	production	production	NOUN
admet-942	444	70	.	.	PUNCT
admet-942	445	1	overcoming	overcome	VERB
admet-942	445	2	the	the	DET
admet-942	445	3	individual	individual	ADJ
admet-942	445	4	challenges	challenge	NOUN
admet-942	445	5	is	be	AUX
admet-942	445	6	the	the	DET
admet-942	445	7	key	key	NOUN
admet-942	445	8	for	for	ADP
admet-942	445	9	translating	translate	VERB
admet-942	445	10	ooc	ooc	PRON
admet-942	445	11	to	to	ADP
admet-942	445	12	cost	cost	NOUN
admet-942	445	13	-	-	PUNCT
admet-942	445	14	effective	effective	ADJ
admet-942	445	15	and	and	CCONJ
admet-942	445	16	sustainable	sustainable	ADJ
admet-942	445	17	implementation	implementation	NOUN
admet-942	445	18	.	.	PUNCT
admet-942	446	1	we	we	PRON
admet-942	446	2	briefly	briefly	ADV
admet-942	446	3	introduce	introduce	VERB
admet-942	446	4	some	some	PRON
admet-942	446	5	of	of	ADP
admet-942	446	6	those	those	DET
admet-942	446	7	relevant	relevant	ADJ
admet-942	446	8	challenges	challenge	NOUN
admet-942	446	9	,	,	PUNCT
admet-942	446	10	however	however	ADV
admet-942	446	11	,	,	PUNCT
admet-942	446	12	more	more	ADJ
admet-942	446	13	insight	insight	NOUN
admet-942	446	14	into	into	ADP
admet-942	446	15	each	each	DET
admet-942	446	16	research	research	NOUN
admet-942	446	17	area	area	NOUN
admet-942	446	18	can	can	AUX
admet-942	446	19	be	be	AUX
admet-942	446	20	found	find	VERB
admet-942	446	21	on	on	ADP
admet-942	446	22	specific	specific	ADJ
admet-942	446	23	reviews	review	NOUN
admet-942	446	24	developed	develop	VERB
admet-942	446	25	for	for	ADP
admet-942	446	26	this	this	DET
admet-942	446	27	purpose	purpose	NOUN
admet-942	446	28	,	,	PUNCT
admet-942	446	29	which	which	PRON
admet-942	446	30	can	can	AUX
admet-942	446	31	be	be	AUX
admet-942	446	32	found	find	VERB
admet-942	446	33	elsewhere	elsewhere	ADV
admet-942	446	34	[	[	X
admet-942	446	35	33–41,137,138	33–41,137,138	NUM
admet-942	446	36	]	]	PUNCT
admet-942	446	37	.	.	PUNCT
admet-942	447	1	challenges	challenge	NOUN
admet-942	447	2	in	in	ADP
admet-942	447	3	fluid	fluid	ADJ
admet-942	447	4	mechanics	mechanic	NOUN
admet-942	447	5	microfluidics	microfluidic	NOUN
admet-942	447	6	are	be	AUX
admet-942	447	7	essential	essential	ADJ
admet-942	447	8	for	for	ADP
admet-942	447	9	the	the	DET
admet-942	447	10	reproduction	reproduction	NOUN
admet-942	447	11	of	of	ADP
admet-942	447	12	the	the	DET
admet-942	447	13	organ	organ	NOUN
admet-942	447	14	’s	’s	PART
admet-942	447	15	conditions	condition	NOUN
admet-942	447	16	in	in	ADP
admet-942	447	17	an	an	DET
admet-942	447	18	ooc	ooc	NOUN
admet-942	447	19	.	.	PUNCT
admet-942	448	1	the	the	DET
admet-942	448	2	use	use	NOUN
admet-942	448	3	of	of	ADP
admet-942	448	4	external	external	ADJ
admet-942	448	5	systems	system	NOUN
admet-942	448	6	is	be	AUX
admet-942	448	7	critical	critical	ADJ
admet-942	448	8	[	[	X
admet-942	448	9	73	73	NUM
admet-942	448	10	]	]	PUNCT
admet-942	448	11	,	,	PUNCT
admet-942	448	12	as	as	ADV
admet-942	448	13	well	well	ADV
admet-942	448	14	as	as	ADP
admet-942	448	15	the	the	DET
admet-942	448	16	3d	3d	NUM
admet-942	448	17	arrangement	arrangement	NOUN
admet-942	448	18	of	of	ADP
admet-942	448	19	the	the	DET
admet-942	448	20	microchannels	microchannel	NOUN
admet-942	448	21	.	.	PUNCT
admet-942	449	1	many	many	ADJ
admet-942	449	2	of	of	ADP
admet-942	449	3	the	the	DET
admet-942	449	4	current	current	ADJ
admet-942	449	5	devices	device	NOUN
admet-942	449	6	present	present	VERB
admet-942	449	7	a	a	DET
admet-942	449	8	gravity	gravity	NOUN
admet-942	449	9	-	-	PUNCT
admet-942	449	10	mediated	mediate	VERB
admet-942	449	11	flow	flow	NOUN
admet-942	449	12	distribution	distribution	NOUN
admet-942	449	13	[	[	X
admet-942	449	14	7,11	7,11	X
admet-942	449	15	]	]	PUNCT
admet-942	449	16	,	,	PUNCT
admet-942	449	17	however	however	ADV
admet-942	449	18	,	,	PUNCT
admet-942	449	19	the	the	DET
admet-942	449	20	development	development	NOUN
admet-942	449	21	of	of	ADP
admet-942	449	22	better	well	ADJ
admet-942	449	23	microfluidic	microfluidic	ADJ
admet-942	449	24	control	control	NOUN
admet-942	449	25	systems	system	NOUN
admet-942	449	26	is	be	AUX
admet-942	449	27	essential	essential	ADJ
admet-942	449	28	to	to	PART
admet-942	449	29	improve	improve	VERB
admet-942	449	30	the	the	DET
admet-942	449	31	reproduction	reproduction	NOUN
admet-942	449	32	and	and	CCONJ
admet-942	449	33	to	to	PART
admet-942	449	34	control	control	VERB
admet-942	449	35	the	the	DET
admet-942	449	36	microflows	microflow	NOUN
admet-942	449	37	that	that	PRON
admet-942	449	38	generate	generate	VERB
admet-942	449	39	more	more	ADJ
admet-942	449	40	bio	bio	ADJ
admet-942	449	41	-	-	ADJ
admet-942	449	42	relevant	relevant	ADJ
admet-942	449	43	conditions	condition	NOUN
admet-942	449	44	within	within	ADP
admet-942	449	45	the	the	DET
admet-942	449	46	chips	chip	NOUN
admet-942	449	47	[	[	X
admet-942	449	48	42,73	42,73	X
admet-942	449	49	]	]	PUNCT
admet-942	449	50	.	.	PUNCT
admet-942	450	1	the	the	DET
admet-942	450	2	development	development	NOUN
admet-942	450	3	of	of	ADP
admet-942	450	4	microfluidic	microfluidic	NOUN
admet-942	450	5	is	be	AUX
admet-942	450	6	,	,	PUNCT
admet-942	450	7	perhaps	perhaps	ADV
admet-942	450	8	,	,	PUNCT
admet-942	450	9	the	the	DET
admet-942	450	10	most	most	ADV
admet-942	450	11	important	important	ADJ
admet-942	450	12	driver	driver	NOUN
admet-942	450	13	in	in	ADP
admet-942	450	14	the	the	DET
admet-942	450	15	progress	progress	NOUN
admet-942	450	16	to	to	ADP
admet-942	450	17	more	more	ADV
admet-942	450	18	complex	complex	ADJ
admet-942	450	19	,	,	PUNCT
admet-942	450	20	robust	robust	ADJ
admet-942	450	21	,	,	PUNCT
admet-942	450	22	significant	significant	ADJ
admet-942	450	23	and	and	CCONJ
admet-942	450	24	scalable	scalable	ADJ
admet-942	450	25	oocs	ooc	NOUN
admet-942	450	26	.	.	PUNCT
admet-942	451	1	for	for	ADP
admet-942	451	2	example	example	NOUN
admet-942	451	3	,	,	PUNCT
admet-942	451	4	hts	hts	PROPN
admet-942	451	5	using	use	VERB
admet-942	451	6	ooc	ooc	NOUN
admet-942	451	7	devices	device	NOUN
admet-942	451	8	requires	require	VERB
admet-942	451	9	improvements	improvement	NOUN
admet-942	451	10	in	in	ADP
admet-942	451	11	microfluidics	microfluidic	NOUN
admet-942	451	12	that	that	PRON
admet-942	451	13	allow	allow	VERB
admet-942	451	14	a	a	DET
admet-942	451	15	better	well	ADV
admet-942	451	16	controlled	control	VERB
admet-942	451	17	perfusion	perfusion	NOUN
admet-942	451	18	,	,	PUNCT
admet-942	451	19	sampling	sampling	NOUN
admet-942	451	20	and	and	CCONJ
admet-942	451	21	cell	cell	NOUN
admet-942	451	22	injection	injection	NOUN
admet-942	451	23	[	[	X
admet-942	451	24	18,139	18,139	NUM
admet-942	451	25	]	]	PUNCT
admet-942	451	26	,	,	PUNCT
admet-942	451	27	while	while	SCONJ
admet-942	451	28	on	on	ADP
admet-942	451	29	the	the	DET
admet-942	451	30	other	other	ADJ
admet-942	451	31	hand	hand	NOUN
admet-942	451	32	,	,	PUNCT
admet-942	451	33	stem	stem	NOUN
admet-942	451	34	cell	cell	NOUN
admet-942	451	35	’s	’s	PART
admet-942	451	36	experimentation	experimentation	NOUN
admet-942	451	37	,	,	PUNCT
admet-942	451	38	production	production	NOUN
admet-942	451	39	and	and	CCONJ
admet-942	451	40	analysis	analysis	NOUN
admet-942	451	41	requires	require	VERB
admet-942	451	42	high	high	ADJ
admet-942	451	43	level	level	NOUN
admet-942	451	44	of	of	ADP
admet-942	451	45	microenvironmental	microenvironmental	ADJ
admet-942	451	46	control	control	NOUN
admet-942	452	1	[	[	X
admet-942	452	2	140	140	NUM
admet-942	452	3	]	]	PUNCT
admet-942	452	4	.	.	PUNCT
admet-942	453	1	chips	chip	NOUN
admet-942	453	2	with	with	ADP
admet-942	453	3	integrated	integrate	VERB
admet-942	453	4	micro	micro	ADJ
admet-942	453	5	pumps	pump	NOUN
admet-942	453	6	and	and	CCONJ
admet-942	453	7	,	,	PUNCT
admet-942	453	8	with	with	ADP
admet-942	453	9	structural	structural	ADJ
admet-942	453	10	and	and	CCONJ
admet-942	453	11	mechanical	mechanical	ADJ
admet-942	453	12	considerations	consideration	NOUN
admet-942	453	13	that	that	PRON
admet-942	453	14	allow	allow	VERB
admet-942	453	15	cell	cell	NOUN
admet-942	453	16	circulation	circulation	NOUN
admet-942	453	17	and	and	CCONJ
admet-942	453	18	passive	passive	ADJ
admet-942	453	19	flow	flow	NOUN
admet-942	453	20	control	control	NOUN
admet-942	453	21	are	be	AUX
admet-942	453	22	some	some	PRON
admet-942	453	23	of	of	ADP
admet-942	453	24	the	the	DET
admet-942	453	25	microfluidic	microfluidic	ADJ
admet-942	453	26	topics	topic	NOUN
admet-942	453	27	with	with	ADP
admet-942	453	28	more	more	ADJ
admet-942	453	29	progress	progress	NOUN
admet-942	453	30	in	in	ADP
admet-942	453	31	the	the	DET
admet-942	453	32	past	past	ADJ
admet-942	453	33	years	year	NOUN
admet-942	454	1	[	[	X
admet-942	454	2	41	41	NUM
admet-942	454	3	]	]	PUNCT
admet-942	454	4	.	.	PUNCT
admet-942	455	1	challenges	challenge	NOUN
admet-942	455	2	on	on	ADP
admet-942	455	3	cell	cell	NOUN
admet-942	455	4	availability	availability	NOUN
admet-942	455	5	physiological	physiological	ADJ
admet-942	455	6	reproducibility	reproducibility	NOUN
admet-942	455	7	of	of	ADP
admet-942	455	8	ooc	ooc	PRON
admet-942	455	9	mainly	mainly	ADV
admet-942	455	10	depends	depend	VERB
admet-942	455	11	on	on	ADP
admet-942	455	12	the	the	DET
admet-942	455	13	cells	cell	NOUN
admet-942	455	14	that	that	PRON
admet-942	455	15	are	be	AUX
admet-942	455	16	employed	employ	VERB
admet-942	455	17	to	to	PART
admet-942	455	18	build	build	VERB
admet-942	455	19	them	they	PRON
admet-942	455	20	.	.	PUNCT
admet-942	456	1	cell	cell	NOUN
admet-942	456	2	availability	availability	NOUN
admet-942	456	3	challenges	challenge	NOUN
admet-942	456	4	in	in	ADP
admet-942	456	5	ooc	ooc	NUM
admet-942	456	6	are	be	AUX
admet-942	456	7	the	the	DET
admet-942	456	8	same	same	ADJ
admet-942	456	9	restrictions	restriction	NOUN
admet-942	456	10	than	than	ADP
admet-942	456	11	those	those	PRON
admet-942	456	12	related	relate	VERB
admet-942	456	13	to	to	ADP
admet-942	456	14	cellular	cellular	ADJ
admet-942	456	15	tissues	tissue	NOUN
admet-942	456	16	:	:	PUNCT
admet-942	456	17	limited	limited	ADJ
admet-942	456	18	access	access	NOUN
admet-942	456	19	to	to	ADP
admet-942	456	20	primary	primary	ADJ
admet-942	456	21	cells	cell	NOUN
admet-942	456	22	and	and	CCONJ
admet-942	456	23	possible	possible	ADJ
admet-942	456	24	dysfunction	dysfunction	NOUN
admet-942	456	25	of	of	ADP
admet-942	456	26	immortalized	immortalized	ADJ
admet-942	456	27	cells	cell	NOUN
admet-942	456	28	[	[	X
admet-942	456	29	7,42	7,42	X
admet-942	456	30	]	]	PUNCT
admet-942	456	31	.	.	PUNCT
admet-942	457	1	to	to	PART
admet-942	457	2	have	have	AUX
admet-942	457	3	different	different	ADJ
admet-942	457	4	cell	cell	NOUN
admet-942	457	5	culture	culture	NOUN
admet-942	457	6	types	type	NOUN
admet-942	457	7	in	in	ADP
admet-942	457	8	the	the	DET
admet-942	457	9	same	same	ADJ
admet-942	457	10	environment	environment	NOUN
admet-942	457	11	brings	bring	VERB
admet-942	457	12	to	to	ADP
admet-942	457	13	an	an	DET
admet-942	457	14	extra	extra	ADJ
admet-942	457	15	difficulty	difficulty	NOUN
admet-942	457	16	,	,	PUNCT
admet-942	457	17	which	which	PRON
admet-942	457	18	is	be	AUX
admet-942	457	19	shared	share	VERB
admet-942	457	20	with	with	ADP
admet-942	457	21	regenerative	regenerative	ADJ
admet-942	457	22	medicine	medicine	NOUN
admet-942	457	23	techniques	technique	NOUN
admet-942	457	24	[	[	X
admet-942	457	25	28,90	28,90	NUM
admet-942	457	26	]	]	PUNCT
admet-942	457	27	.	.	PUNCT
admet-942	458	1	obtaining	obtain	VERB
admet-942	458	2	reproducible	reproducible	ADJ
admet-942	458	3	tissues	tissue	NOUN
admet-942	458	4	,	,	PUNCT
admet-942	458	5	suitable	suitable	ADJ
admet-942	458	6	for	for	ADP
admet-942	458	7	application	application	NOUN
admet-942	458	8	in	in	ADP
admet-942	458	9	ooc	ooc	NOUN
admet-942	458	10	systems	system	NOUN
admet-942	458	11	,	,	PUNCT
admet-942	458	12	requires	require	VERB
admet-942	458	13	the	the	DET
admet-942	458	14	development	development	NOUN
admet-942	458	15	of	of	ADP
admet-942	458	16	more	more	ADJ
admet-942	458	17	and	and	CCONJ
admet-942	458	18	better	well	ADJ
admet-942	458	19	techniques	technique	NOUN
admet-942	458	20	for	for	ADP
admet-942	458	21	the	the	DET
admet-942	458	22	culture	culture	NOUN
admet-942	458	23	,	,	PUNCT
admet-942	458	24	maturation	maturation	NOUN
admet-942	458	25	and	and	CCONJ
admet-942	458	26	differentiation	differentiation	NOUN
admet-942	458	27	of	of	ADP
admet-942	458	28	pluripotent	pluripotent	ADJ
admet-942	458	29	cells	cell	NOUN
admet-942	458	30	,	,	PUNCT
admet-942	458	31	as	as	ADV
admet-942	458	32	well	well	ADV
admet-942	458	33	as	as	ADP
admet-942	458	34	the	the	DET
admet-942	458	35	standardization	standardization	NOUN
admet-942	458	36	of	of	ADP
admet-942	458	37	the	the	DET
admet-942	458	38	obtention	obtention	NOUN
admet-942	458	39	of	of	ADP
admet-942	458	40	protocols	protocol	NOUN
admet-942	458	41	[	[	X
admet-942	458	42	5,55,90	5,55,90	NUM
admet-942	458	43	]	]	PUNCT
admet-942	458	44	.	.	PUNCT
admet-942	459	1	major	major	ADJ
admet-942	459	2	breakthroughs	breakthrough	NOUN
admet-942	459	3	in	in	ADP
admet-942	459	4	this	this	DET
admet-942	459	5	field	field	NOUN
admet-942	459	6	include	include	VERB
admet-942	459	7	relevant	relevant	ADJ
admet-942	459	8	experimentation	experimentation	NOUN
admet-942	459	9	on	on	ADP
admet-942	459	10	novel	novel	NOUN
admet-942	459	11	and	and	CCONJ
admet-942	459	12	standardized	standardized	ADJ
admet-942	459	13	methods	method	NOUN
admet-942	459	14	to	to	PART
admet-942	459	15	obtain	obtain	VERB
admet-942	459	16	and	and	CCONJ
admet-942	459	17	differentiate	differentiate	VERB
admet-942	459	18	stem	stem	NOUN
admet-942	459	19	cells	cell	NOUN
admet-942	459	20	into	into	ADP
admet-942	459	21	functional	functional	ADJ
admet-942	459	22	organ	organ	NOUN
admet-942	459	23	models	model	NOUN
admet-942	459	24	[	[	X
admet-942	459	25	141–143	141–143	NUM
admet-942	459	26	]	]	PUNCT
admet-942	459	27	,	,	PUNCT
admet-942	459	28	and	and	CCONJ
admet-942	459	29	the	the	DET
admet-942	459	30	continuous	continuous	ADJ
admet-942	459	31	efforts	effort	NOUN
admet-942	459	32	for	for	ADP
admet-942	459	33	the	the	DET
admet-942	459	34	development	development	NOUN
admet-942	459	35	of	of	ADP
admet-942	459	36	a	a	DET
admet-942	459	37	blood	blood	NOUN
admet-942	459	38	substitute	substitute	NOUN
admet-942	459	39	,	,	PUNCT
admet-942	459	40	a	a	DET
admet-942	459	41	representative	representative	ADJ
admet-942	459	42	universal	universal	ADJ
admet-942	459	43	cell	cell	NOUN
admet-942	459	44	medium	medium	NOUN
admet-942	459	45	for	for	ADP
admet-942	459	46	ooc	ooc	PRON
admet-942	459	47	[	[	X
admet-942	459	48	41	41	NUM
admet-942	459	49	]	]	PUNCT
admet-942	459	50	.	.	PUNCT
admet-942	460	1	challenges	challenge	NOUN
admet-942	460	2	in	in	ADP
admet-942	460	3	materials	material	NOUN
admet-942	460	4	engineering	engineering	NOUN
admet-942	460	5	in	in	ADP
admet-942	460	6	this	this	DET
admet-942	460	7	area	area	NOUN
admet-942	460	8	it	it	PRON
admet-942	460	9	is	be	AUX
admet-942	460	10	required	require	VERB
admet-942	460	11	to	to	PART
admet-942	460	12	develop	develop	VERB
admet-942	460	13	materials	material	NOUN
admet-942	460	14	that	that	PRON
admet-942	460	15	accomplish	accomplish	VERB
admet-942	460	16	all	all	PRON
admet-942	460	17	–	–	PUNCT
admet-942	460	18	or	or	CCONJ
admet-942	460	19	most	most	ADJ
admet-942	460	20	of	of	ADP
admet-942	460	21	–	–	PUNCT
admet-942	460	22	the	the	DET
admet-942	460	23	application	application	NOUN
admet-942	460	24	criteria	criterion	NOUN
admet-942	460	25	in	in	ADP
admet-942	460	26	an	an	DET
admet-942	460	27	ooc	ooc	NOUN
admet-942	460	28	,	,	PUNCT
admet-942	460	29	such	such	ADJ
admet-942	460	30	as	as	ADP
admet-942	460	31	plasticity	plasticity	NOUN
admet-942	460	32	,	,	PUNCT
admet-942	460	33	elasticity	elasticity	NOUN
admet-942	460	34	,	,	PUNCT
admet-942	460	35	transparency	transparency	NOUN
admet-942	460	36	,	,	PUNCT
admet-942	460	37	biocompatibility	biocompatibility	NOUN
admet-942	460	38	or	or	CCONJ
admet-942	460	39	versatility	versatility	NOUN
admet-942	461	1	[	[	X
admet-942	461	2	7,63	7,63	X
admet-942	461	3	]	]	PUNCT
admet-942	461	4	.	.	PUNCT
admet-942	462	1	these	these	DET
admet-942	462	2	materials	material	NOUN
admet-942	462	3	must	must	AUX
admet-942	462	4	be	be	AUX
admet-942	462	5	inert	inert	ADJ
admet-942	462	6	to	to	ADP
admet-942	462	7	the	the	DET
admet-942	462	8	drugs	drug	NOUN
admet-942	462	9	to	to	PART
admet-942	462	10	evaluate	evaluate	VERB
admet-942	462	11	[	[	X
admet-942	462	12	44,75	44,75	NOUN
admet-942	462	13	]	]	PUNCT
admet-942	462	14	and	and	CCONJ
admet-942	462	15	exhibit	exhibit	VERB
admet-942	462	16	easy	easy	ADJ
admet-942	462	17	printing	printing	NOUN
admet-942	462	18	,	,	PUNCT
admet-942	462	19	while	while	SCONJ
admet-942	462	20	achieving	achieve	VERB
admet-942	462	21	adequate	adequate	ADJ
admet-942	462	22	mimicry	mimicry	NOUN
admet-942	462	23	with	with	ADP
admet-942	462	24	living	live	VERB
admet-942	462	25	tissues	tissue	NOUN
admet-942	462	26	[	[	X
admet-942	462	27	28	28	NUM
admet-942	462	28	]	]	PUNCT
admet-942	462	29	.	.	PUNCT
admet-942	463	1	the	the	DET
admet-942	463	2	materials	material	NOUN
admet-942	463	3	that	that	PRON
admet-942	463	4	are	be	AUX
admet-942	463	5	currently	currently	ADV
admet-942	463	6	used	use	VERB
admet-942	463	7	do	do	AUX
admet-942	463	8	not	not	PART
admet-942	463	9	meet	meet	VERB
admet-942	463	10	all	all	DET
admet-942	463	11	the	the	DET
admet-942	463	12	requirements	requirement	NOUN
admet-942	463	13	simultaneously	simultaneously	ADV
admet-942	463	14	.	.	PUNCT
admet-942	464	1	for	for	ADP
admet-942	464	2	example	example	NOUN
admet-942	464	3	,	,	PUNCT
admet-942	464	4	pdms	pdms	NOUN
admet-942	464	5	is	be	AUX
admet-942	464	6	one	one	NUM
admet-942	464	7	of	of	ADP
admet-942	464	8	the	the	DET
admet-942	464	9	most	most	ADV
admet-942	464	10	widely	widely	ADV
admet-942	464	11	used	use	VERB
admet-942	464	12	materials	material	NOUN
admet-942	464	13	to	to	PART
admet-942	464	14	manufacture	manufacture	VERB
admet-942	464	15	ooc	ooc	PRON
admet-942	464	16	due	due	ADP
admet-942	464	17	to	to	ADP
admet-942	464	18	its	its	PRON
admet-942	464	19	versatility	versatility	NOUN
admet-942	464	20	and	and	CCONJ
admet-942	464	21	biocompatibility	biocompatibility	NOUN
admet-942	464	22	,	,	PUNCT
admet-942	464	23	nevertheless	nevertheless	ADV
admet-942	464	24	,	,	PUNCT
admet-942	464	25	it	it	PRON
admet-942	464	26	has	have	AUX
admet-942	464	27	shown	show	VERB
admet-942	464	28	a	a	DET
admet-942	464	29	tendency	tendency	NOUN
admet-942	464	30	to	to	PART
admet-942	464	31	absorb	absorb	VERB
admet-942	464	32	small	small	ADJ
admet-942	464	33	molecules	molecule	NOUN
admet-942	464	34	,	,	PUNCT
admet-942	464	35	such	such	ADJ
admet-942	464	36	as	as	ADP
admet-942	464	37	many	many	ADJ
admet-942	464	38	of	of	ADP
admet-942	464	39	the	the	DET
admet-942	464	40	drugs	drug	NOUN
admet-942	464	41	evaluated	evaluate	VERB
admet-942	465	1	[	[	X
admet-942	465	2	10,18,30,144	10,18,30,144	NUM
admet-942	465	3	]	]	X
admet-942	465	4	.	.	PUNCT
admet-942	466	1	therefore	therefore	ADV
admet-942	466	2	,	,	PUNCT
admet-942	466	3	the	the	DET
admet-942	466	4	discovery	discovery	NOUN
admet-942	466	5	of	of	ADP
admet-942	466	6	intelligent	intelligent	ADJ
admet-942	466	7	materials	material	NOUN
admet-942	466	8	that	that	PRON
admet-942	466	9	can	can	AUX
admet-942	466	10	change	change	VERB
admet-942	466	11	their	their	PRON
admet-942	466	12	shape	shape	NOUN
admet-942	466	13	and	and	CCONJ
admet-942	466	14	reactivity	reactivity	NOUN
admet-942	466	15	in	in	ADP
admet-942	466	16	front	front	NOUN
admet-942	466	17	of	of	ADP
admet-942	466	18	different	different	ADJ
admet-942	466	19	stimuli	stimulus	NOUN
admet-942	466	20	,	,	PUNCT
admet-942	466	21	known	know	VERB
admet-942	466	22	as	as	ADP
admet-942	466	23	four	four	NUM
admet-942	466	24	-	-	PUNCT
admet-942	466	25	dimensional	dimensional	ADJ
admet-942	466	26	printing	printing	NOUN
admet-942	466	27	,	,	PUNCT
admet-942	466	28	is	be	AUX
admet-942	466	29	a	a	DET
admet-942	466	30	promising	promising	ADJ
admet-942	466	31	strategy	strategy	NOUN
admet-942	466	32	for	for	ADP
admet-942	466	33	the	the	DET
admet-942	466	34	future	future	NOUN
admet-942	466	35	ooc	ooc	NOUN
admet-942	466	36	[	[	X
admet-942	466	37	58	58	NUM
admet-942	466	38	]	]	PUNCT
admet-942	466	39	.	.	PUNCT
admet-942	467	1	recent	recent	ADJ
admet-942	467	2	advances	advance	NOUN
admet-942	467	3	include	include	VERB
admet-942	467	4	the	the	DET
admet-942	467	5	introduction	introduction	NOUN
admet-942	467	6	of	of	ADP
admet-942	467	7	a	a	DET
admet-942	467	8	variety	variety	NOUN
admet-942	467	9	of	of	ADP
admet-942	467	10	biocompatible	biocompatible	ADJ
admet-942	467	11	and	and	CCONJ
admet-942	467	12	thermoplastic	thermoplastic	ADJ
admet-942	467	13	materials	material	NOUN
admet-942	467	14	that	that	PRON
admet-942	467	15	are	be	AUX
admet-942	467	16	presumably	presumably	ADV
admet-942	467	17	more	more	ADV
admet-942	467	18	suitable	suitable	ADJ
admet-942	467	19	for	for	ADP
admet-942	467	20	large	large	ADJ
admet-942	467	21	scale	scale	NOUN
admet-942	467	22	manufacturing	manufacturing	NOUN
admet-942	467	23	processes	process	NOUN
admet-942	467	24	[	[	X
admet-942	467	25	41	41	NUM
admet-942	467	26	]	]	PUNCT
admet-942	467	27	.	.	PUNCT
admet-942	468	1	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	468	2	r.	r.	PROPN
admet-942	468	3	vargas	vargas	PROPN
admet-942	468	4	,	,	PUNCT
admet-942	468	5	a.	a.	NOUN
admet-942	468	6	egurbide	egurbide	NOUN
admet-942	468	7	-	-	PUNCT
admet-942	468	8	sifre	sifre	NOUN
admet-942	468	9	and	and	CCONJ
admet-942	468	10	l.	l.	PROPN
admet-942	468	11	medina	medina	PROPN
admet-942	468	12	admet	admet	PROPN
admet-942	468	13	&	&	CCONJ
admet-942	468	14	dmpk	dmpk	PROPN
admet-942	468	15	9(2	9(2	NUM
admet-942	468	16	)	)	PUNCT
admet-942	468	17	(	(	PUNCT
admet-942	468	18	2021	2021	NUM
admet-942	468	19	)	)	PUNCT
admet-942	468	20	111	111	NUM
admet-942	468	21	-	-	SYM
admet-942	468	22	141	141	NUM
admet-942	468	23	130	130	NUM
admet-942	468	24	challenges	challenge	NOUN
admet-942	468	25	in	in	ADP
admet-942	468	26	measurement	measurement	NOUN
admet-942	468	27	systems	system	NOUN
admet-942	468	28	the	the	DET
admet-942	468	29	evolution	evolution	NOUN
admet-942	468	30	of	of	ADP
admet-942	468	31	ooc	ooc	PROPN
admet-942	468	32	requires	require	VERB
admet-942	468	33	an	an	DET
admet-942	468	34	improvement	improvement	NOUN
admet-942	468	35	in	in	ADP
admet-942	468	36	the	the	DET
admet-942	468	37	development	development	NOUN
admet-942	468	38	of	of	ADP
admet-942	468	39	specific	specific	ADJ
admet-942	468	40	electrodes	electrode	NOUN
admet-942	468	41	and/or	and/or	CCONJ
admet-942	468	42	biosensors	biosensor	NOUN
admet-942	468	43	[	[	X
admet-942	468	44	7,28	7,28	X
admet-942	468	45	]	]	X
admet-942	468	46	with	with	ADP
admet-942	468	47	high	high	ADJ
admet-942	468	48	performance	performance	NOUN
admet-942	468	49	,	,	PUNCT
admet-942	468	50	high	high	ADJ
admet-942	468	51	sensitivity	sensitivity	NOUN
admet-942	468	52	and	and	CCONJ
admet-942	468	53	high	high	ADJ
admet-942	468	54	specificity	specificity	NOUN
admet-942	468	55	[	[	X
admet-942	468	56	18,53,80	18,53,80	NUM
admet-942	468	57	]	]	PUNCT
admet-942	468	58	.	.	PUNCT
admet-942	469	1	the	the	DET
admet-942	469	2	high	high	ADJ
admet-942	469	3	sensitivity	sensitivity	NOUN
admet-942	469	4	is	be	AUX
admet-942	469	5	required	require	VERB
admet-942	469	6	due	due	ADP
admet-942	469	7	to	to	ADP
admet-942	469	8	the	the	DET
admet-942	469	9	low	low	ADJ
admet-942	469	10	amount	amount	NOUN
admet-942	469	11	of	of	ADP
admet-942	469	12	metabolic	metabolic	NOUN
admet-942	469	13	secretions	secretion	NOUN
admet-942	469	14	[	[	X
admet-942	469	15	3	3	NUM
admet-942	469	16	]	]	PUNCT
admet-942	469	17	.	.	PUNCT
admet-942	470	1	moreover	moreover	ADV
admet-942	470	2	,	,	PUNCT
admet-942	470	3	it	it	PRON
admet-942	470	4	must	must	AUX
admet-942	470	5	be	be	AUX
admet-942	470	6	possible	possible	ADJ
admet-942	470	7	to	to	PART
admet-942	470	8	measure	measure	VERB
admet-942	470	9	the	the	DET
admet-942	470	10	tissue	tissue	NOUN
admet-942	470	11	response	response	NOUN
admet-942	470	12	at	at	ADP
admet-942	470	13	many	many	ADJ
admet-942	470	14	other	other	ADJ
admet-942	470	15	levels	level	NOUN
admet-942	470	16	,	,	PUNCT
admet-942	470	17	as	as	ADV
admet-942	470	18	well	well	ADV
admet-942	470	19	as	as	ADP
admet-942	470	20	the	the	DET
admet-942	470	21	concentration	concentration	NOUN
admet-942	470	22	variations	variation	NOUN
admet-942	470	23	of	of	ADP
admet-942	470	24	the	the	DET
admet-942	470	25	specific	specific	ADJ
admet-942	470	26	substance	substance	NOUN
admet-942	470	27	[	[	X
admet-942	470	28	42	42	NUM
admet-942	470	29	]	]	PUNCT
admet-942	470	30	.	.	PUNCT
admet-942	471	1	therefore	therefore	ADV
admet-942	471	2	,	,	PUNCT
admet-942	471	3	ooc	ooc	NOUN
admet-942	471	4	systems	system	NOUN
admet-942	471	5	must	must	AUX
admet-942	471	6	have	have	VERB
admet-942	471	7	the	the	DET
admet-942	471	8	ability	ability	NOUN
admet-942	471	9	to	to	PART
admet-942	471	10	detect	detect	VERB
admet-942	471	11	small	small	ADJ
admet-942	471	12	non	non	ADJ
admet-942	471	13	-	-	ADJ
admet-942	471	14	lethal	lethal	ADJ
admet-942	471	15	changes	change	NOUN
admet-942	471	16	that	that	PRON
admet-942	471	17	affect	affect	VERB
admet-942	471	18	functionality	functionality	NOUN
admet-942	471	19	at	at	ADP
admet-942	471	20	the	the	DET
admet-942	471	21	cellular	cellular	ADJ
admet-942	471	22	level	level	NOUN
admet-942	471	23	[	[	X
admet-942	471	24	7,41	7,41	NOUN
admet-942	471	25	]	]	X
admet-942	471	26	.	.	PUNCT
admet-942	472	1	more	more	ADV
admet-942	472	2	feasible	feasible	ADJ
admet-942	472	3	,	,	PUNCT
admet-942	472	4	adaptable	adaptable	ADJ
admet-942	472	5	to	to	ADP
admet-942	472	6	hts	ht	NOUN
admet-942	472	7	and	and	CCONJ
admet-942	472	8	scalable	scalable	ADJ
admet-942	472	9	bio	bio	NOUN
admet-942	472	10	-	-	PUNCT
admet-942	472	11	assays	assay	NOUN
admet-942	472	12	also	also	ADV
admet-942	472	13	require	require	VERB
admet-942	472	14	microfluid	microfluid	ADJ
admet-942	472	15	regulators	regulator	NOUN
admet-942	472	16	such	such	ADJ
admet-942	472	17	as	as	ADP
admet-942	472	18	valves	valve	NOUN
admet-942	472	19	,	,	PUNCT
admet-942	472	20	pumps	pump	NOUN
admet-942	472	21	,	,	PUNCT
admet-942	472	22	mixers	mixer	NOUN
admet-942	472	23	and	and	CCONJ
admet-942	472	24	other	other	ADJ
admet-942	472	25	functional	functional	ADJ
admet-942	472	26	elements	element	NOUN
admet-942	472	27	to	to	PART
admet-942	472	28	get	get	VERB
admet-942	472	29	cell	cell	NOUN
admet-942	472	30	perfusion	perfusion	NOUN
admet-942	472	31	with	with	ADP
admet-942	472	32	fresh	fresh	ADJ
admet-942	472	33	media	medium	NOUN
admet-942	472	34	and	and	CCONJ
admet-942	472	35	assay	assay	ADJ
admet-942	472	36	reagents	reagent	NOUN
admet-942	472	37	[	[	X
admet-942	472	38	139	139	NUM
admet-942	472	39	]	]	PUNCT
admet-942	472	40	.	.	PUNCT
admet-942	473	1	these	these	DET
admet-942	473	2	systems	system	NOUN
admet-942	473	3	must	must	AUX
admet-942	473	4	allow	allow	VERB
admet-942	473	5	non	non	ADJ
admet-942	473	6	-	-	ADJ
admet-942	473	7	invasive	invasive	ADJ
admet-942	473	8	parallel	parallel	ADJ
admet-942	473	9	measurements	measurement	NOUN
admet-942	473	10	,	,	PUNCT
admet-942	473	11	automation	automation	NOUN
admet-942	473	12	and	and	CCONJ
admet-942	473	13	flexibility	flexibility	NOUN
admet-942	473	14	in	in	ADP
admet-942	473	15	order	order	NOUN
admet-942	473	16	to	to	PART
admet-942	473	17	fit	fit	VERB
admet-942	473	18	hts	ht	NOUN
admet-942	473	19	programs	program	NOUN
admet-942	473	20	used	use	VERB
admet-942	473	21	by	by	ADP
admet-942	473	22	big	big	ADJ
admet-942	473	23	pharma	pharma	PROPN
admet-942	473	24	companies	company	NOUN
admet-942	473	25	to	to	PART
admet-942	473	26	evaluate	evaluate	VERB
admet-942	473	27	their	their	PRON
admet-942	473	28	compound	compound	NOUN
admet-942	473	29	libraries	library	NOUN
admet-942	473	30	[	[	X
admet-942	473	31	4,18,29,41,75	4,18,29,41,75	NOUN
admet-942	473	32	]	]	X
admet-942	473	33	.	.	PUNCT
admet-942	474	1	commercially	commercially	ADV
admet-942	474	2	available	available	ADJ
admet-942	474	3	micro	micro	NOUN
admet-942	474	4	-	-	NOUN
admet-942	474	5	sensors	sensor	NOUN
admet-942	474	6	of	of	ADP
admet-942	474	7	thermos	thermos	PROPN
admet-942	474	8	responsive	responsive	ADJ
admet-942	474	9	materials	material	NOUN
admet-942	474	10	and	and	CCONJ
admet-942	474	11	electrodes	electrode	NOUN
admet-942	474	12	,	,	PUNCT
admet-942	474	13	as	as	ADV
admet-942	474	14	well	well	ADV
admet-942	474	15	as	as	ADP
admet-942	474	16	optical	optical	ADJ
admet-942	474	17	methods	method	NOUN
admet-942	474	18	for	for	ADP
admet-942	474	19	ph	ph	NOUN
admet-942	474	20	and	and	CCONJ
admet-942	474	21	oxygen	oxygen	NOUN
admet-942	474	22	determination	determination	NOUN
admet-942	474	23	,	,	PUNCT
admet-942	474	24	have	have	AUX
admet-942	474	25	been	be	AUX
admet-942	474	26	successfully	successfully	ADV
admet-942	474	27	incorporated	incorporate	VERB
admet-942	474	28	to	to	ADP
admet-942	474	29	ooc	ooc	NOUN
admet-942	474	30	devices	device	NOUN
admet-942	474	31	,	,	PUNCT
admet-942	475	1	[	[	X
admet-942	475	2	41	41	NUM
admet-942	475	3	]	]	PUNCT
admet-942	475	4	in	in	ADP
admet-942	475	5	addition	addition	NOUN
admet-942	475	6	to	to	ADP
admet-942	475	7	several	several	ADJ
admet-942	475	8	prototypes	prototype	NOUN
admet-942	475	9	of	of	ADP
admet-942	475	10	organic	organic	ADJ
admet-942	475	11	biotransistors	biotransistor	NOUN
admet-942	476	1	[	[	X
admet-942	476	2	145	145	NUM
admet-942	476	3	]	]	PUNCT
admet-942	476	4	.	.	PUNCT
admet-942	477	1	in	in	ADP
admet-942	477	2	the	the	DET
admet-942	477	3	particular	particular	ADJ
admet-942	477	4	case	case	NOUN
admet-942	477	5	of	of	ADP
admet-942	477	6	a	a	DET
admet-942	477	7	bbb	bbb	NOUN
admet-942	477	8	-	-	PUNCT
admet-942	477	9	on	on	ADP
admet-942	477	10	-	-	PUNCT
admet-942	477	11	a	a	DET
admet-942	477	12	-	-	PUNCT
admet-942	477	13	chip	chip	NOUN
admet-942	477	14	,	,	PUNCT
admet-942	477	15	teer	teer	PROPN
admet-942	477	16	has	have	AUX
admet-942	477	17	become	become	VERB
admet-942	477	18	the	the	DET
admet-942	477	19	most	most	ADV
admet-942	477	20	popular	popular	ADJ
admet-942	477	21	online	online	ADJ
admet-942	477	22	sense	sense	NOUN
admet-942	477	23	method	method	NOUN
admet-942	477	24	.	.	PUNCT
admet-942	478	1	but	but	CCONJ
admet-942	478	2	other	other	ADJ
admet-942	478	3	alternatives	alternative	NOUN
admet-942	478	4	such	such	ADJ
admet-942	478	5	as	as	ADP
admet-942	478	6	physical	physical	ADJ
admet-942	478	7	sensors	sensor	NOUN
admet-942	478	8	,	,	PUNCT
admet-942	478	9	with	with	ADP
admet-942	478	10	the	the	DET
admet-942	478	11	ability	ability	NOUN
admet-942	478	12	of	of	ADP
admet-942	478	13	measuring	measure	VERB
admet-942	478	14	small	small	ADJ
admet-942	478	15	concentrations	concentration	NOUN
admet-942	478	16	of	of	ADP
admet-942	478	17	metabolites	metabolite	NOUN
admet-942	478	18	,	,	PUNCT
admet-942	478	19	and	and	CCONJ
admet-942	478	20	a	a	DET
admet-942	478	21	variety	variety	NOUN
admet-942	478	22	of	of	ADP
admet-942	478	23	biosensors	biosensor	NOUN
admet-942	478	24	,	,	PUNCT
admet-942	478	25	bioreceptors	bioreceptor	NOUN
admet-942	478	26	that	that	PRON
admet-942	478	27	generate	generate	VERB
admet-942	478	28	an	an	DET
admet-942	478	29	electric	electric	ADJ
admet-942	478	30	signal	signal	NOUN
admet-942	478	31	after	after	ADP
admet-942	478	32	binding	bind	VERB
admet-942	478	33	a	a	DET
admet-942	478	34	biological	biological	ADJ
admet-942	478	35	target	target	NOUN
admet-942	478	36	,	,	PUNCT
admet-942	478	37	have	have	AUX
admet-942	478	38	been	be	AUX
admet-942	478	39	proposed	propose	VERB
admet-942	478	40	(	(	PUNCT
admet-942	478	41	figure	figure	NOUN
admet-942	478	42	12	12	NUM
admet-942	478	43	)	)	PUNCT
admet-942	479	1	[	[	X
admet-942	479	2	146	146	NUM
admet-942	479	3	]	]	PUNCT
admet-942	479	4	.	.	PUNCT
admet-942	480	1	software	software	NOUN
admet-942	480	2	-	-	PUNCT
admet-942	480	3	driven	drive	VERB
admet-942	480	4	analyses	analysis	NOUN
admet-942	480	5	of	of	ADP
admet-942	480	6	optical	optical	ADJ
admet-942	480	7	recordings	recording	NOUN
admet-942	480	8	have	have	AUX
admet-942	480	9	been	be	AUX
admet-942	480	10	described	describe	VERB
admet-942	480	11	for	for	ADP
admet-942	480	12	several	several	ADJ
admet-942	480	13	cellular	cellular	ADJ
admet-942	480	14	functions	function	NOUN
admet-942	480	15	such	such	ADJ
admet-942	480	16	as	as	ADP
admet-942	480	17	the	the	DET
admet-942	480	18	heart	heart	NOUN
admet-942	480	19	rate	rate	NOUN
admet-942	480	20	[	[	X
admet-942	480	21	82	82	NUM
admet-942	480	22	]	]	PUNCT
admet-942	480	23	,	,	PUNCT
admet-942	480	24	which	which	PRON
admet-942	480	25	can	can	AUX
admet-942	480	26	be	be	AUX
admet-942	480	27	used	use	VERB
admet-942	480	28	to	to	PART
admet-942	480	29	evaluate	evaluate	VERB
admet-942	480	30	other	other	ADJ
admet-942	480	31	related	relate	VERB
admet-942	480	32	muscular	muscular	ADJ
admet-942	480	33	functions	function	NOUN
admet-942	480	34	.	.	PUNCT
admet-942	481	1	figure	figure	NOUN
admet-942	481	2	12	12	NUM
admet-942	481	3	.	.	PUNCT
admet-942	482	1	biosensors	biosensor	NOUN
admet-942	482	2	and	and	CCONJ
admet-942	482	3	sensors	sensor	NOUN
admet-942	482	4	on	on	ADP
admet-942	482	5	bbb	bbb	PROPN
admet-942	482	6	-	-	PUNCT
admet-942	482	7	on	on	ADP
admet-942	482	8	-	-	PUNCT
admet-942	482	9	a	a	DET
admet-942	482	10	-	-	PUNCT
admet-942	482	11	chip	chip	NOUN
admet-942	482	12	transducing	transducing	NOUN
admet-942	482	13	signals	signal	NOUN
admet-942	482	14	to	to	ADP
admet-942	482	15	a	a	DET
admet-942	482	16	pc	pc	NOUN
admet-942	482	17	or	or	CCONJ
admet-942	482	18	mobile	mobile	ADJ
admet-942	482	19	interface	interface	NOUN
admet-942	482	20	.	.	PUNCT
admet-942	483	1	reproduced	reproduce	VERB
admet-942	483	2	from	from	ADP
admet-942	483	3	[	[	X
admet-942	483	4	146	146	NUM
admet-942	483	5	]	]	PUNCT
admet-942	483	6	under	under	ADP
admet-942	483	7	terms	term	NOUN
admet-942	483	8	of	of	ADP
admet-942	483	9	the	the	DET
admet-942	483	10	creative	creative	ADJ
admet-942	483	11	commons	common	NOUN
admet-942	483	12	attribution	attribution	NOUN
admet-942	483	13	license	license	NOUN
admet-942	483	14	.	.	PUNCT
admet-942	484	1	copyright	copyright	NOUN
admet-942	484	2	(	(	PUNCT
admet-942	484	3	2019	2019	NUM
admet-942	484	4	)	)	PUNCT
admet-942	484	5	.	.	PUNCT
admet-942	485	1	challenges	challenge	NOUN
admet-942	485	2	on	on	ADP
admet-942	485	3	industrial	industrial	ADJ
admet-942	485	4	scale	scale	NOUN
admet-942	485	5	production	production	NOUN
admet-942	485	6	there	there	PRON
admet-942	485	7	are	be	VERB
admet-942	485	8	many	many	ADJ
admet-942	485	9	ooc	ooc	ADJ
admet-942	485	10	prototypes	prototype	NOUN
admet-942	485	11	that	that	PRON
admet-942	485	12	have	have	AUX
admet-942	485	13	been	be	AUX
admet-942	485	14	presented	present	VERB
admet-942	485	15	only	only	ADV
admet-942	485	16	as	as	ADP
admet-942	485	17	a	a	DET
admet-942	485	18	pilot	pilot	NOUN
admet-942	485	19	test	test	NOUN
admet-942	485	20	at	at	ADP
admet-942	485	21	laboratory	laboratory	NOUN
admet-942	485	22	level	level	NOUN
admet-942	485	23	.	.	PUNCT
admet-942	486	1	the	the	DET
admet-942	486	2	success	success	NOUN
admet-942	486	3	of	of	ADP
admet-942	486	4	an	an	DET
admet-942	486	5	ooc	ooc	NOUN
admet-942	486	6	system	system	NOUN
admet-942	486	7	in	in	ADP
admet-942	486	8	solving	solve	VERB
admet-942	486	9	real	real	ADJ
admet-942	486	10	problems	problem	NOUN
admet-942	486	11	depends	depend	VERB
admet-942	486	12	on	on	ADP
admet-942	486	13	how	how	SCONJ
admet-942	486	14	rigorously	rigorously	ADV
admet-942	486	15	it	it	PRON
admet-942	486	16	fits	fit	VERB
admet-942	486	17	the	the	DET
admet-942	486	18	real	real	ADJ
admet-942	486	19	model	model	NOUN
admet-942	486	20	,	,	PUNCT
admet-942	486	21	but	but	CCONJ
admet-942	486	22	furthermore	furthermore	ADV
admet-942	486	23	,	,	PUNCT
admet-942	486	24	on	on	ADP
admet-942	486	25	how	how	SCONJ
admet-942	486	26	easily	easily	ADV
admet-942	486	27	it	it	PRON
admet-942	486	28	can	can	AUX
admet-942	486	29	be	be	AUX
admet-942	486	30	transferred	transfer	VERB
admet-942	486	31	to	to	ADP
admet-942	486	32	industrial	industrial	ADJ
admet-942	486	33	production	production	NOUN
admet-942	486	34	.	.	PUNCT
admet-942	487	1	in	in	ADP
admet-942	487	2	many	many	ADJ
admet-942	487	3	cases	case	NOUN
admet-942	487	4	,	,	PUNCT
admet-942	487	5	the	the	DET
admet-942	487	6	ooc	ooc	NOUN
admet-942	487	7	prototype	prototype	NOUN
admet-942	487	8	admet	admet	PROPN
admet-942	487	9	&	&	CCONJ
admet-942	487	10	dmpk	dmpk	PROPN
admet-942	487	11	9(2	9(2	NUM
admet-942	487	12	)	)	PUNCT
admet-942	487	13	(	(	PUNCT
admet-942	487	14	2021	2021	NUM
admet-942	487	15	)	)	PUNCT
admet-942	487	16	111	111	NUM
admet-942	487	17	-	-	SYM
admet-942	487	18	141	141	NUM
admet-942	487	19	organ	organ	NOUN
admet-942	487	20	-	-	PUNCT
admet-942	487	21	on	on	ADP
admet-942	487	22	-	-	PUNCT
admet-942	487	23	a	a	DET
admet-942	487	24	-	-	PUNCT
admet-942	487	25	chip	chip	NOUN
admet-942	487	26	systems	system	NOUN
admet-942	487	27	for	for	ADP
admet-942	487	28	new	new	ADJ
admet-942	487	29	drugs	drug	NOUN
admet-942	487	30	development	development	NOUN
admet-942	487	31	doi	doi	PROPN
admet-942	487	32	:	:	PUNCT
admet-942	487	33	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	NOUN
admet-942	487	34	131	131	NUM
admet-942	487	35	is	be	AUX
admet-942	487	36	obtained	obtain	VERB
admet-942	487	37	through	through	ADP
admet-942	487	38	an	an	DET
admet-942	487	39	effective	effective	ADJ
admet-942	487	40	3d	3d	NUM
admet-942	487	41	printing	printing	NOUN
admet-942	487	42	technique	technique	NOUN
admet-942	487	43	,	,	PUNCT
admet-942	487	44	but	but	CCONJ
admet-942	487	45	it	it	PRON
admet-942	487	46	is	be	AUX
admet-942	487	47	inefficient	inefficient	ADJ
admet-942	487	48	for	for	ADP
admet-942	487	49	large	large	ADJ
admet-942	487	50	scale	scale	NOUN
admet-942	487	51	due	due	ADP
admet-942	487	52	to	to	ADP
admet-942	487	53	the	the	DET
admet-942	487	54	low	low	ADJ
admet-942	487	55	speed	speed	NOUN
admet-942	487	56	at	at	ADP
admet-942	487	57	which	which	PRON
admet-942	487	58	the	the	DET
admet-942	487	59	structures	structure	NOUN
admet-942	487	60	are	be	AUX
admet-942	487	61	created	create	VERB
admet-942	487	62	[	[	X
admet-942	487	63	7,11,28	7,11,28	NUM
admet-942	487	64	]	]	X
admet-942	487	65	.	.	PUNCT
admet-942	488	1	low	low	ADJ
admet-942	488	2	cost	cost	NOUN
admet-942	488	3	or	or	CCONJ
admet-942	488	4	reusable	reusable	ADJ
admet-942	488	5	materials	material	NOUN
admet-942	488	6	could	could	AUX
admet-942	488	7	lead	lead	VERB
admet-942	488	8	to	to	ADP
admet-942	488	9	a	a	DET
admet-942	488	10	more	more	ADV
admet-942	488	11	widespread	widespread	ADJ
admet-942	488	12	use	use	NOUN
admet-942	488	13	of	of	ADP
admet-942	488	14	ooc	ooc	NOUN
admet-942	488	15	in	in	ADP
admet-942	488	16	early	early	ADJ
admet-942	488	17	stages	stage	NOUN
admet-942	488	18	of	of	ADP
admet-942	488	19	drug	drug	NOUN
admet-942	488	20	discovery	discovery	NOUN
admet-942	488	21	[	[	X
admet-942	488	22	143	143	NUM
admet-942	488	23	]	]	PUNCT
admet-942	488	24	.	.	PUNCT
admet-942	489	1	massive	massive	ADJ
admet-942	489	2	parallelization	parallelization	NOUN
admet-942	489	3	and	and	CCONJ
admet-942	489	4	automation	automation	NOUN
admet-942	489	5	of	of	ADP
admet-942	489	6	ooc	ooc	PROPN
admet-942	489	7	systems	system	NOUN
admet-942	489	8	are	be	AUX
admet-942	489	9	among	among	ADP
admet-942	489	10	the	the	DET
admet-942	489	11	biggest	big	ADJ
admet-942	489	12	challenges	challenge	NOUN
admet-942	489	13	to	to	PART
admet-942	489	14	overcome	overcome	VERB
admet-942	489	15	in	in	ADP
admet-942	489	16	order	order	NOUN
admet-942	489	17	to	to	PART
admet-942	489	18	meet	meet	VERB
admet-942	489	19	industrial	industrial	ADJ
admet-942	489	20	requirements	requirement	NOUN
admet-942	489	21	of	of	ADP
admet-942	489	22	hts	hts	PROPN
admet-942	489	23	[	[	X
admet-942	489	24	18	18	NUM
admet-942	489	25	]	]	PUNCT
admet-942	489	26	.	.	PUNCT
admet-942	490	1	the	the	DET
admet-942	490	2	work	work	NOUN
admet-942	490	3	of	of	ADP
admet-942	490	4	ramadan	ramadan	PROPN
admet-942	490	5	and	and	CCONJ
admet-942	490	6	zourob	zourob	X
admet-942	490	7	[	[	X
admet-942	490	8	137	137	NUM
admet-942	490	9	]	]	PUNCT
admet-942	490	10	contains	contain	VERB
admet-942	490	11	a	a	DET
admet-942	490	12	comprehensive	comprehensive	ADJ
admet-942	490	13	review	review	NOUN
admet-942	490	14	not	not	PART
admet-942	490	15	only	only	ADV
admet-942	490	16	of	of	ADP
admet-942	490	17	the	the	DET
admet-942	490	18	main	main	ADJ
admet-942	490	19	challenges	challenge	NOUN
admet-942	490	20	,	,	PUNCT
admet-942	490	21	but	but	CCONJ
admet-942	490	22	of	of	ADP
admet-942	490	23	specific	specific	ADJ
admet-942	490	24	strategies	strategy	NOUN
admet-942	490	25	to	to	PART
admet-942	490	26	solve	solve	VERB
admet-942	490	27	them	they	PRON
admet-942	490	28	,	,	PUNCT
admet-942	490	29	trends	trend	NOUN
admet-942	490	30	and	and	CCONJ
admet-942	490	31	examples	example	NOUN
admet-942	490	32	of	of	ADP
admet-942	490	33	the	the	DET
admet-942	490	34	main	main	ADJ
admet-942	490	35	industrialization	industrialization	NOUN
admet-942	490	36	activities	activity	NOUN
admet-942	490	37	of	of	ADP
admet-942	490	38	some	some	PRON
admet-942	490	39	of	of	ADP
admet-942	490	40	the	the	DET
admet-942	490	41	developing	develop	VERB
admet-942	490	42	ooc	ooc	NOUN
admet-942	490	43	systems	system	NOUN
admet-942	490	44	.	.	PUNCT
admet-942	491	1	the	the	DET
admet-942	491	2	more	more	ADV
admet-942	491	3	sophisticated	sophisticated	ADJ
admet-942	491	4	an	an	DET
admet-942	491	5	ooc	ooc	NOUN
admet-942	491	6	becomes	become	VERB
admet-942	491	7	,	,	PUNCT
admet-942	491	8	the	the	PRON
admet-942	491	9	more	more	ADJ
admet-942	491	10	it	it	PRON
admet-942	491	11	needs	need	VERB
admet-942	491	12	to	to	PART
admet-942	491	13	be	be	AUX
admet-942	491	14	controlled	control	VERB
admet-942	491	15	,	,	PUNCT
admet-942	491	16	which	which	PRON
admet-942	491	17	increases	increase	VERB
admet-942	491	18	its	its	PRON
admet-942	491	19	cost	cost	NOUN
admet-942	491	20	and	and	CCONJ
admet-942	491	21	limits	limit	VERB
admet-942	491	22	its	its	PRON
admet-942	491	23	usege	usege	NOUN
admet-942	491	24	.	.	PUNCT
admet-942	492	1	to	to	PART
admet-942	492	2	ensure	ensure	VERB
admet-942	492	3	reproducibility	reproducibility	NOUN
admet-942	492	4	of	of	ADP
admet-942	492	5	oocs	ooc	NOUN
admet-942	492	6	[	[	X
admet-942	492	7	49	49	NUM
admet-942	492	8	]	]	X
admet-942	492	9	specific	specific	ADJ
admet-942	492	10	tests	test	NOUN
admet-942	492	11	must	must	AUX
admet-942	492	12	be	be	AUX
admet-942	492	13	developed	develop	VERB
admet-942	492	14	in	in	ADP
admet-942	492	15	parallel	parallel	NOUN
admet-942	492	16	for	for	ADP
admet-942	492	17	the	the	DET
admet-942	492	18	quality	quality	NOUN
admet-942	492	19	control	control	NOUN
admet-942	492	20	of	of	ADP
admet-942	492	21	the	the	DET
admet-942	492	22	devices	device	NOUN
admet-942	493	1	[	[	X
admet-942	493	2	133	133	NUM
admet-942	493	3	]	]	PUNCT
admet-942	493	4	.	.	PUNCT
admet-942	494	1	besides	besides	SCONJ
admet-942	494	2	any	any	DET
admet-942	494	3	limitation	limitation	NOUN
admet-942	494	4	,	,	PUNCT
admet-942	494	5	the	the	DET
admet-942	494	6	number	number	NOUN
admet-942	494	7	of	of	ADP
admet-942	494	8	commercially	commercially	ADV
admet-942	494	9	available	available	ADJ
admet-942	494	10	ooc	ooc	NOUN
admet-942	494	11	devices	device	NOUN
admet-942	494	12	,	,	PUNCT
admet-942	494	13	new	new	ADJ
admet-942	494	14	start	start	VERB
admet-942	494	15	-	-	PUNCT
admet-942	494	16	up	up	ADP
admet-942	494	17	companies	company	NOUN
admet-942	494	18	and	and	CCONJ
admet-942	494	19	patent	patent	NOUN
admet-942	494	20	applications	application	NOUN
admet-942	494	21	have	have	AUX
admet-942	494	22	considerably	considerably	ADV
admet-942	494	23	increased	increase	VERB
admet-942	494	24	these	these	DET
admet-942	494	25	last	last	ADJ
admet-942	494	26	years	year	NOUN
admet-942	495	1	[	[	X
admet-942	495	2	136	136	NUM
admet-942	495	3	]	]	PUNCT
admet-942	495	4	.	.	PUNCT
admet-942	496	1	ooc	ooc	PRON
admet-942	496	2	validation	validation	NOUN
admet-942	496	3	the	the	DET
admet-942	496	4	validation	validation	NOUN
admet-942	496	5	of	of	ADP
admet-942	496	6	ooc	ooc	NOUN
admet-942	496	7	systems	system	NOUN
admet-942	496	8	is	be	AUX
admet-942	496	9	particularly	particularly	ADV
admet-942	496	10	important	important	ADJ
admet-942	496	11	for	for	SCONJ
admet-942	496	12	regulatory	regulatory	ADJ
admet-942	496	13	agencies	agency	NOUN
admet-942	496	14	to	to	PART
admet-942	496	15	accept	accept	VERB
admet-942	496	16	them	they	PRON
admet-942	496	17	as	as	ADP
admet-942	496	18	clinical	clinical	ADJ
admet-942	496	19	and	and	CCONJ
admet-942	496	20	experimental	experimental	ADJ
admet-942	496	21	alternatives	alternative	NOUN
admet-942	496	22	,	,	PUNCT
admet-942	496	23	especially	especially	ADV
admet-942	496	24	in	in	ADP
admet-942	496	25	toxicity	toxicity	NOUN
admet-942	496	26	trials	trial	NOUN
admet-942	496	27	[	[	X
admet-942	496	28	13,42,43	13,42,43	NUM
admet-942	496	29	]	]	PUNCT
admet-942	496	30	.	.	PUNCT
admet-942	497	1	so	so	ADV
admet-942	497	2	far	far	ADV
admet-942	497	3	,	,	PUNCT
admet-942	497	4	many	many	ADJ
admet-942	497	5	ooc	ooc	ADJ
admet-942	497	6	developments	development	NOUN
admet-942	497	7	correspond	correspond	VERB
admet-942	497	8	to	to	ADP
admet-942	497	9	isolated	isolated	ADJ
admet-942	497	10	publications	publication	NOUN
admet-942	497	11	with	with	ADP
admet-942	497	12	a	a	DET
admet-942	497	13	lack	lack	NOUN
admet-942	497	14	of	of	ADP
admet-942	497	15	standardized	standardized	ADJ
admet-942	497	16	protocols	protocol	NOUN
admet-942	497	17	for	for	ADP
admet-942	497	18	operation	operation	NOUN
admet-942	497	19	,	,	PUNCT
admet-942	497	20	data	datum	NOUN
admet-942	497	21	collection	collection	NOUN
admet-942	497	22	and	and	CCONJ
admet-942	497	23	analyses	analysis	NOUN
admet-942	497	24	[	[	X
admet-942	497	25	63	63	NUM
admet-942	497	26	]	]	PUNCT
admet-942	497	27	.	.	PUNCT
admet-942	498	1	direct	direct	ADJ
admet-942	498	2	comparisons	comparison	NOUN
admet-942	498	3	require	require	VERB
admet-942	498	4	specific	specific	ADJ
admet-942	498	5	clinical	clinical	ADJ
admet-942	498	6	studies	study	NOUN
admet-942	498	7	and	and	CCONJ
admet-942	498	8	long	long	ADJ
admet-942	498	9	-	-	PUNCT
admet-942	498	10	term	term	NOUN
admet-942	498	11	gathered	gather	VERB
admet-942	498	12	data	datum	NOUN
admet-942	498	13	.	.	PUNCT
admet-942	499	1	thus	thus	ADV
admet-942	499	2	,	,	PUNCT
admet-942	499	3	many	many	ADJ
admet-942	499	4	ooc	ooc	NOUN
admet-942	499	5	system	system	NOUN
admet-942	499	6	improvements	improvement	NOUN
admet-942	499	7	are	be	AUX
admet-942	499	8	performed	perform	VERB
admet-942	499	9	in	in	ADP
admet-942	499	10	collaboration	collaboration	NOUN
admet-942	499	11	between	between	ADP
admet-942	499	12	academia	academia	NOUN
admet-942	499	13	,	,	PUNCT
admet-942	499	14	industry	industry	NOUN
admet-942	499	15	and	and	CCONJ
admet-942	499	16	regulatory	regulatory	ADJ
admet-942	499	17	authorities	authority	NOUN
admet-942	499	18	[	[	X
admet-942	499	19	7,50	7,50	X
admet-942	499	20	]	]	PUNCT
admet-942	499	21	.	.	PUNCT
admet-942	500	1	regulatory	regulatory	ADJ
admet-942	500	2	agencies	agency	NOUN
admet-942	500	3	,	,	PUNCT
admet-942	500	4	academia	academia	NOUN
admet-942	500	5	and	and	CCONJ
admet-942	500	6	several	several	ADJ
admet-942	500	7	companies	company	NOUN
admet-942	500	8	have	have	AUX
admet-942	500	9	been	be	AUX
admet-942	500	10	conducting	conduct	VERB
admet-942	500	11	efforts	effort	NOUN
admet-942	500	12	to	to	PART
admet-942	500	13	establish	establish	VERB
admet-942	500	14	industrial	industrial	ADJ
admet-942	500	15	standards	standard	NOUN
admet-942	500	16	and	and	CCONJ
admet-942	500	17	validation	validation	NOUN
admet-942	500	18	guidelines	guideline	NOUN
admet-942	500	19	for	for	ADP
admet-942	500	20	ooc	ooc	NOUN
admet-942	500	21	technologies	technology	NOUN
admet-942	500	22	[	[	X
admet-942	500	23	136	136	NUM
admet-942	500	24	]	]	PUNCT
admet-942	500	25	.	.	PUNCT
admet-942	501	1	the	the	DET
admet-942	501	2	replication	replication	NOUN
admet-942	501	3	of	of	ADP
admet-942	501	4	already	already	ADV
admet-942	501	5	-	-	PUNCT
admet-942	501	6	conducted	conduct	VERB
admet-942	501	7	trials	trial	NOUN
admet-942	501	8	executed	execute	VERB
admet-942	501	9	with	with	ADP
admet-942	501	10	approved	approve	VERB
admet-942	501	11	products	product	NOUN
admet-942	501	12	and	and	CCONJ
admet-942	501	13	the	the	DET
admet-942	501	14	comparison	comparison	NOUN
admet-942	501	15	of	of	ADP
admet-942	501	16	their	their	PRON
admet-942	501	17	results	result	NOUN
admet-942	501	18	with	with	ADP
admet-942	501	19	the	the	DET
admet-942	501	20	results	result	NOUN
admet-942	501	21	obtained	obtain	VERB
admet-942	501	22	with	with	ADP
admet-942	501	23	approved	approve	VERB
admet-942	501	24	assays	assay	NOUN
admet-942	501	25	is	be	AUX
admet-942	501	26	one	one	NUM
admet-942	501	27	way	way	NOUN
admet-942	501	28	of	of	ADP
admet-942	501	29	achieving	achieve	VERB
admet-942	501	30	the	the	DET
admet-942	501	31	acceptance	acceptance	NOUN
admet-942	501	32	of	of	ADP
admet-942	501	33	ooc	ooc	NOUN
admet-942	501	34	systems	system	NOUN
admet-942	501	35	as	as	ADP
admet-942	501	36	alternative	alternative	ADJ
admet-942	501	37	methods	method	NOUN
admet-942	501	38	for	for	ADP
admet-942	501	39	pre	pre	ADJ
admet-942	501	40	-	-	ADJ
admet-942	501	41	clinical	clinical	ADJ
admet-942	501	42	–	–	PUNCT
admet-942	501	43	or	or	CCONJ
admet-942	501	44	even	even	ADV
admet-942	501	45	clinical	clinical	ADJ
admet-942	501	46	–	–	PUNCT
admet-942	501	47	studies	study	NOUN
admet-942	501	48	[	[	X
admet-942	501	49	7,136	7,136	NUM
admet-942	501	50	]	]	PUNCT
admet-942	501	51	.	.	PUNCT
admet-942	502	1	ooc	ooc	PRON
admet-942	502	2	could	could	AUX
admet-942	502	3	be	be	AUX
admet-942	502	4	used	use	VERB
admet-942	502	5	to	to	PART
admet-942	502	6	replicate	replicate	VERB
admet-942	502	7	cases	case	NOUN
admet-942	502	8	of	of	ADP
admet-942	502	9	clinical	clinical	ADJ
admet-942	502	10	studies	study	NOUN
admet-942	502	11	in	in	ADP
admet-942	502	12	which	which	PRON
admet-942	502	13	severe	severe	ADJ
admet-942	502	14	adverse	adverse	ADJ
admet-942	502	15	events	event	NOUN
admet-942	502	16	were	be	AUX
admet-942	502	17	not	not	PART
admet-942	502	18	detected	detect	VERB
admet-942	502	19	pre	pre	ADJ
admet-942	502	20	-	-	ADJ
admet-942	502	21	clinical	clinical	ADJ
admet-942	502	22	stages	stage	NOUN
admet-942	502	23	and	and	CCONJ
admet-942	502	24	drugs	drug	NOUN
admet-942	502	25	had	have	VERB
admet-942	502	26	to	to	PART
admet-942	502	27	be	be	AUX
admet-942	502	28	withdrawn	withdraw	VERB
admet-942	502	29	from	from	ADP
admet-942	502	30	the	the	DET
admet-942	502	31	market	market	NOUN
admet-942	502	32	,	,	PUNCT
admet-942	502	33	therefore	therefore	ADV
admet-942	502	34	,	,	PUNCT
admet-942	502	35	it	it	PRON
admet-942	502	36	could	could	AUX
admet-942	502	37	be	be	AUX
admet-942	502	38	determined	determine	VERB
admet-942	502	39	if	if	SCONJ
admet-942	502	40	this	this	DET
admet-942	502	41	technology	technology	NOUN
admet-942	502	42	has	have	VERB
admet-942	502	43	a	a	DET
admet-942	502	44	greater	great	ADJ
admet-942	502	45	or	or	CCONJ
admet-942	502	46	equal	equal	ADJ
admet-942	502	47	predictive	predictive	ADJ
admet-942	502	48	capacity	capacity	NOUN
admet-942	502	49	[	[	X
admet-942	502	50	44	44	NUM
admet-942	502	51	]	]	PUNCT
admet-942	502	52	.	.	PUNCT
admet-942	503	1	conclusions	conclusion	NOUN
admet-942	503	2	there	there	PRON
admet-942	503	3	is	be	VERB
admet-942	503	4	growing	grow	VERB
admet-942	503	5	evidence	evidence	NOUN
admet-942	503	6	that	that	SCONJ
admet-942	503	7	ooc	ooc	NOUN
admet-942	503	8	systems	system	NOUN
admet-942	503	9	are	be	AUX
admet-942	503	10	a	a	DET
admet-942	503	11	novel	novel	ADJ
admet-942	503	12	tool	tool	NOUN
admet-942	503	13	that	that	PRON
admet-942	503	14	will	will	AUX
admet-942	503	15	facilitate	facilitate	VERB
admet-942	503	16	the	the	DET
admet-942	503	17	search	search	NOUN
admet-942	503	18	,	,	PUNCT
admet-942	503	19	development	development	NOUN
admet-942	503	20	and	and	CCONJ
admet-942	503	21	evaluation	evaluation	NOUN
admet-942	503	22	of	of	ADP
admet-942	503	23	new	new	ADJ
admet-942	503	24	drugs	drug	NOUN
admet-942	503	25	.	.	PUNCT
admet-942	504	1	these	these	DET
admet-942	504	2	systems	system	NOUN
admet-942	504	3	show	show	VERB
admet-942	504	4	characteristics	characteristic	NOUN
admet-942	504	5	of	of	ADP
admet-942	504	6	reproducibility	reproducibility	NOUN
admet-942	504	7	,	,	PUNCT
admet-942	504	8	adaptability	adaptability	NOUN
admet-942	504	9	and	and	CCONJ
admet-942	504	10	versatility	versatility	NOUN
admet-942	504	11	that	that	PRON
admet-942	504	12	make	make	VERB
admet-942	504	13	them	they	PRON
admet-942	504	14	a	a	DET
admet-942	504	15	potential	potential	ADJ
admet-942	504	16	alternative	alternative	NOUN
admet-942	504	17	to	to	ADP
admet-942	504	18	the	the	DET
admet-942	504	19	use	use	NOUN
admet-942	504	20	of	of	ADP
admet-942	504	21	experimental	experimental	ADJ
admet-942	504	22	animals	animal	NOUN
admet-942	504	23	.	.	PUNCT
admet-942	505	1	oocs	ooc	NOUN
admet-942	505	2	are	be	AUX
admet-942	505	3	an	an	DET
admet-942	505	4	evolution	evolution	NOUN
admet-942	505	5	of	of	ADP
admet-942	505	6	2d	2d	NUM
admet-942	505	7	cell	cell	NOUN
admet-942	505	8	cultures	culture	NOUN
admet-942	505	9	,	,	PUNCT
admet-942	505	10	thus	thus	ADV
admet-942	505	11	maintaining	maintain	VERB
admet-942	505	12	some	some	PRON
admet-942	505	13	of	of	ADP
admet-942	505	14	the	the	DET
admet-942	505	15	characteristics	characteristic	NOUN
admet-942	505	16	of	of	ADP
admet-942	505	17	cell	cell	NOUN
admet-942	505	18	tissue	tissue	NOUN
admet-942	505	19	evaluations	evaluation	NOUN
admet-942	505	20	.	.	PUNCT
admet-942	506	1	however	however	ADV
admet-942	506	2	,	,	PUNCT
admet-942	506	3	these	these	DET
admet-942	506	4	new	new	ADJ
admet-942	506	5	systems	system	NOUN
admet-942	506	6	overcome	overcome	VERB
admet-942	506	7	many	many	ADJ
admet-942	506	8	of	of	ADP
admet-942	506	9	the	the	DET
admet-942	506	10	conventional	conventional	ADJ
admet-942	506	11	cell	cell	NOUN
admet-942	506	12	cultures	culture	NOUN
admet-942	506	13	weaknesses	weakness	NOUN
admet-942	506	14	,	,	PUNCT
admet-942	506	15	such	such	ADJ
admet-942	506	16	as	as	ADP
admet-942	506	17	the	the	DET
admet-942	506	18	poor	poor	ADJ
admet-942	506	19	extrapolation	extrapolation	NOUN
admet-942	506	20	to	to	ADP
admet-942	506	21	an	an	DET
admet-942	506	22	entire	entire	ADJ
admet-942	506	23	organism	organism	NOUN
admet-942	506	24	.	.	PUNCT
admet-942	507	1	ooc	ooc	PRON
admet-942	507	2	simulate	simulate	VERB
admet-942	507	3	the	the	DET
admet-942	507	4	real	real	ADJ
admet-942	507	5	microenvironment	microenvironment	NOUN
admet-942	507	6	and	and	CCONJ
admet-942	507	7	the	the	DET
admet-942	507	8	key	key	ADJ
admet-942	507	9	functional	functional	ADJ
admet-942	507	10	aspects	aspect	NOUN
admet-942	507	11	of	of	ADP
admet-942	507	12	organs	organ	NOUN
admet-942	507	13	at	at	ADP
admet-942	507	14	a	a	DET
admet-942	507	15	microscopic	microscopic	ADJ
admet-942	507	16	scale	scale	NOUN
admet-942	507	17	.	.	PUNCT
admet-942	508	1	this	this	PRON
admet-942	508	2	enables	enable	VERB
admet-942	508	3	the	the	DET
admet-942	508	4	study	study	NOUN
admet-942	508	5	of	of	ADP
admet-942	508	6	drugs	drug	NOUN
admet-942	508	7	as	as	ADV
admet-942	508	8	well	well	ADV
admet-942	508	9	as	as	ADP
admet-942	508	10	the	the	DET
admet-942	508	11	investigation	investigation	NOUN
admet-942	508	12	of	of	ADP
admet-942	508	13	physiological	physiological	ADJ
admet-942	508	14	and	and	CCONJ
admet-942	508	15	physio	physio	NOUN
admet-942	508	16	-	-	PUNCT
admet-942	508	17	pathological	pathological	ADJ
admet-942	508	18	phenomena	phenomenon	NOUN
admet-942	508	19	.	.	PUNCT
admet-942	509	1	the	the	DET
admet-942	509	2	construction	construction	NOUN
admet-942	509	3	of	of	ADP
admet-942	509	4	ooc	ooc	NOUN
admet-942	509	5	requires	require	VERB
admet-942	509	6	a	a	DET
admet-942	509	7	deep	deep	ADJ
admet-942	509	8	understanding	understanding	NOUN
admet-942	509	9	of	of	ADP
admet-942	509	10	the	the	DET
admet-942	509	11	real	real	ADJ
admet-942	509	12	functionality	functionality	NOUN
admet-942	509	13	of	of	ADP
admet-942	509	14	the	the	DET
admet-942	509	15	tissue	tissue	NOUN
admet-942	509	16	/	/	SYM
admet-942	509	17	organ	organ	NOUN
admet-942	509	18	to	to	PART
admet-942	509	19	be	be	AUX
admet-942	509	20	studied	study	VERB
admet-942	509	21	and	and	CCONJ
admet-942	509	22	mimicked	mimic	VERB
admet-942	509	23	.	.	PUNCT
admet-942	510	1	in	in	ADP
admet-942	510	2	many	many	ADJ
admet-942	510	3	cases	case	NOUN
admet-942	510	4	,	,	PUNCT
admet-942	510	5	this	this	DET
admet-942	510	6	knowledge	knowledge	NOUN
admet-942	510	7	is	be	AUX
admet-942	510	8	limited	limited	ADJ
admet-942	510	9	,	,	PUNCT
admet-942	510	10	thus	thus	ADV
admet-942	510	11	leading	lead	VERB
admet-942	510	12	to	to	ADP
admet-942	510	13	a	a	DET
admet-942	510	14	synergy	synergy	NOUN
admet-942	510	15	between	between	ADP
admet-942	510	16	the	the	DET
admet-942	510	17	research	research	NOUN
admet-942	510	18	in	in	ADP
admet-942	510	19	physiology	physiology	NOUN
admet-942	510	20	and	and	CCONJ
admet-942	510	21	the	the	DET
admet-942	510	22	development	development	NOUN
admet-942	510	23	of	of	ADP
admet-942	510	24	oocs	ooc	NOUN
admet-942	510	25	.	.	PUNCT
admet-942	511	1	these	these	DET
admet-942	511	2	systems	system	NOUN
admet-942	511	3	could	could	AUX
admet-942	511	4	–	–	PUNCT
admet-942	511	5	scientifically	scientifically	ADV
admet-942	511	6	and	and	CCONJ
admet-942	511	7	financially	financially	ADV
admet-942	511	8	–	–	PUNCT
admet-942	511	9	promote	promote	VERB
admet-942	511	10	the	the	DET
admet-942	511	11	development	development	NOUN
admet-942	511	12	of	of	ADP
admet-942	511	13	new	new	ADJ
admet-942	511	14	drugs	drug	NOUN
admet-942	511	15	.	.	PUNCT
admet-942	512	1	risk	risk	NOUN
admet-942	512	2	reduction	reduction	NOUN
admet-942	512	3	could	could	AUX
admet-942	512	4	revolutionize	revolutionize	VERB
admet-942	512	5	the	the	DET
admet-942	512	6	way	way	NOUN
admet-942	512	7	big	big	ADJ
admet-942	512	8	pharmaceutical	pharmaceutical	ADJ
admet-942	512	9	companies	company	NOUN
admet-942	512	10	focus	focus	VERB
admet-942	512	11	their	their	PRON
admet-942	512	12	development	development	NOUN
admet-942	512	13	efforts	effort	NOUN
admet-942	512	14	,	,	PUNCT
admet-942	512	15	as	as	ADV
admet-942	512	16	well	well	ADV
admet-942	512	17	as	as	ADP
admet-942	512	18	the	the	DET
admet-942	512	19	approach	approach	NOUN
admet-942	512	20	of	of	ADP
admet-942	512	21	how	how	SCONJ
admet-942	512	22	clinical	clinical	ADJ
admet-942	512	23	and	and	CCONJ
admet-942	512	24	preclinical	preclinical	ADJ
admet-942	512	25	studies	study	NOUN
admet-942	512	26	are	be	AUX
admet-942	512	27	conducted	conduct	VERB
admet-942	512	28	.	.	PUNCT
admet-942	513	1	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	513	2	r.	r.	PROPN
admet-942	513	3	vargas	vargas	PROPN
admet-942	513	4	,	,	PUNCT
admet-942	513	5	a.	a.	NOUN
admet-942	513	6	egurbide	egurbide	NOUN
admet-942	513	7	-	-	PUNCT
admet-942	513	8	sifre	sifre	NOUN
admet-942	513	9	and	and	CCONJ
admet-942	513	10	l.	l.	PROPN
admet-942	513	11	medina	medina	PROPN
admet-942	513	12	admet	admet	PROPN
admet-942	513	13	&	&	CCONJ
admet-942	513	14	dmpk	dmpk	PROPN
admet-942	513	15	9(2	9(2	NUM
admet-942	513	16	)	)	PUNCT
admet-942	513	17	(	(	PUNCT
admet-942	513	18	2021	2021	NUM
admet-942	513	19	)	)	PUNCT
admet-942	513	20	111	111	NUM
admet-942	513	21	-	-	SYM
admet-942	513	22	141	141	NUM
admet-942	513	23	132	132	NUM
admet-942	513	24	ooc	ooc	NOUN
admet-942	513	25	's	's	PART
admet-942	513	26	progress	progress	NOUN
admet-942	513	27	efforts	effort	NOUN
admet-942	513	28	must	must	AUX
admet-942	513	29	converge	converge	VERB
admet-942	513	30	on	on	ADP
admet-942	513	31	the	the	DET
admet-942	513	32	development	development	NOUN
admet-942	513	33	of	of	ADP
admet-942	513	34	systems	system	NOUN
admet-942	513	35	with	with	ADP
admet-942	513	36	enough	enough	ADJ
admet-942	513	37	representativeness	representativeness	NOUN
admet-942	513	38	,	,	PUNCT
admet-942	513	39	reproducibility	reproducibility	NOUN
admet-942	513	40	,	,	PUNCT
admet-942	513	41	scalability	scalability	NOUN
admet-942	513	42	and	and	CCONJ
admet-942	513	43	suitability	suitability	NOUN
admet-942	513	44	for	for	ADP
admet-942	513	45	hts	hts	PROPN
admet-942	513	46	,	,	PUNCT
admet-942	513	47	which	which	PRON
admet-942	513	48	maintain	maintain	VERB
admet-942	513	49	at	at	ADP
admet-942	513	50	the	the	DET
admet-942	513	51	same	same	ADJ
admet-942	513	52	time	time	NOUN
admet-942	513	53	reasonable	reasonable	ADJ
admet-942	513	54	production	production	NOUN
admet-942	513	55	and	and	CCONJ
admet-942	513	56	implementations	implementation	NOUN
admet-942	513	57	costs	cost	NOUN
admet-942	513	58	.	.	PUNCT
admet-942	514	1	although	although	SCONJ
admet-942	514	2	science	science	NOUN
admet-942	514	3	is	be	AUX
admet-942	514	4	far	far	ADV
admet-942	514	5	from	from	ADP
admet-942	514	6	being	be	AUX
admet-942	514	7	able	able	ADJ
admet-942	514	8	to	to	PART
admet-942	514	9	mimic	mimic	VERB
admet-942	514	10	at	at	ADP
admet-942	514	11	100	100	NUM
admet-942	514	12	%	%	NOUN
admet-942	514	13	the	the	DET
admet-942	514	14	human	human	ADJ
admet-942	514	15	body	body	NOUN
admet-942	514	16	in	in	ADP
admet-942	514	17	a	a	DET
admet-942	514	18	laboratory	laboratory	NOUN
admet-942	514	19	,	,	PUNCT
admet-942	514	20	any	any	DET
admet-942	514	21	advance	advance	NOUN
admet-942	514	22	will	will	AUX
admet-942	514	23	increase	increase	VERB
admet-942	514	24	the	the	DET
admet-942	514	25	predictive	predictive	ADJ
admet-942	514	26	potential	potential	NOUN
admet-942	514	27	of	of	ADP
admet-942	514	28	ooc	ooc	NOUN
admet-942	514	29	systems	system	NOUN
admet-942	514	30	and	and	CCONJ
admet-942	514	31	will	will	AUX
admet-942	514	32	provide	provide	VERB
admet-942	514	33	innumerable	innumerable	ADJ
admet-942	514	34	benefits	benefit	NOUN
admet-942	514	35	for	for	ADP
admet-942	514	36	new	new	ADJ
admet-942	514	37	drugs	drug	NOUN
admet-942	514	38	development	development	NOUN
admet-942	514	39	.	.	PUNCT
admet-942	515	1	acknowledgements	acknowledgement	NOUN
admet-942	515	2	:	:	PUNCT
admet-942	515	3	this	this	DET
admet-942	515	4	work	work	NOUN
admet-942	515	5	was	be	AUX
admet-942	515	6	possible	possible	ADJ
admet-942	515	7	thanks	thank	NOUN
admet-942	515	8	to	to	ADP
admet-942	515	9	the	the	DET
admet-942	515	10	grant	grant	NOUN
admet-942	515	11	of	of	ADP
admet-942	515	12	the	the	DET
admet-942	515	13	office	office	NOUN
admet-942	515	14	of	of	ADP
admet-942	515	15	international	international	ADJ
admet-942	515	16	affairs	affair	NOUN
admet-942	515	17	of	of	ADP
admet-942	515	18	the	the	DET
admet-942	515	19	university	university	PROPN
admet-942	515	20	of	of	ADP
admet-942	515	21	costa	costa	PROPN
admet-942	515	22	rica	rica	PROPN
admet-942	515	23	(	(	PUNCT
admet-942	515	24	oaice-64	oaice-64	PROPN
admet-942	515	25	-	-	PUNCT
admet-942	515	26	2019	2019	NUM
admet-942	515	27	)	)	PUNCT
admet-942	515	28	.	.	PUNCT
admet-942	516	1	the	the	DET
admet-942	516	2	authors	author	NOUN
admet-942	516	3	would	would	AUX
admet-942	516	4	like	like	VERB
admet-942	516	5	to	to	PART
admet-942	516	6	acknowledge	acknowledge	VERB
admet-942	516	7	lic	lic	PROPN
admet-942	516	8	.	.	PUNCT
admet-942	517	1	pablo	pablo	PROPN
admet-942	517	2	vargas	vargas	PROPN
admet-942	517	3	monge	monge	PROPN
admet-942	517	4	for	for	ADP
admet-942	517	5	his	his	PRON
admet-942	517	6	contribution	contribution	NOUN
admet-942	517	7	with	with	ADP
admet-942	517	8	the	the	DET
admet-942	517	9	elaboration	elaboration	NOUN
admet-942	517	10	of	of	ADP
admet-942	517	11	the	the	DET
admet-942	517	12	graphical	graphical	ADJ
admet-942	517	13	abstract	abstract	NOUN
admet-942	517	14	.	.	PUNCT
admet-942	518	1	conflict	conflict	NOUN
admet-942	518	2	of	of	ADP
admet-942	518	3	interest	interest	NOUN
admet-942	518	4	:	:	PUNCT
admet-942	518	5	the	the	DET
admet-942	518	6	authors	author	NOUN
admet-942	518	7	have	have	VERB
admet-942	518	8	no	no	DET
admet-942	518	9	conflicts	conflict	NOUN
admet-942	518	10	of	of	ADP
admet-942	518	11	interest	interest	NOUN
admet-942	518	12	to	to	PART
admet-942	518	13	declare	declare	VERB
admet-942	518	14	.	.	PUNCT
admet-942	519	1	references	reference	NOUN
admet-942	519	2	[	[	X
admet-942	519	3	1	1	NUM
admet-942	519	4	]	]	PUNCT
admet-942	519	5	r.	r.	PROPN
admet-942	519	6	mittal	mittal	PROPN
admet-942	519	7	,	,	PUNCT
admet-942	519	8	f.w	f.w	PROPN
admet-942	519	9	.	.	PROPN
admet-942	519	10	woo	woo	PROPN
admet-942	519	11	,	,	PUNCT
admet-942	519	12	c.s	c.s	PROPN
admet-942	519	13	.	.	PROPN
admet-942	519	14	castro	castro	PROPN
admet-942	519	15	,	,	PUNCT
admet-942	519	16	m.a	m.a	PROPN
admet-942	519	17	.	.	PROPN
admet-942	519	18	cohen	cohen	PROPN
admet-942	519	19	,	,	PUNCT
admet-942	519	20	j.	j.	PROPN
admet-942	519	21	karanxha	karanxha	PROPN
admet-942	519	22	,	,	PUNCT
admet-942	519	23	j.	j.	PROPN
admet-942	519	24	mittal	mittal	PROPN
admet-942	519	25	,	,	PUNCT
admet-942	519	26	t.	t.	PROPN
admet-942	519	27	chhibber	chhibber	PROPN
admet-942	519	28	,	,	PUNCT
admet-942	519	29	v.m	v.m	PROPN
admet-942	519	30	.	.	PROPN
admet-942	519	31	jhaveri	jhaveri	PROPN
admet-942	519	32	.	.	PUNCT
admet-942	520	1	organon	organon	PROPN
admet-942	520	2	-	-	PUNCT
admet-942	520	3	chip	chip	NOUN
admet-942	520	4	models	model	NOUN
admet-942	520	5	:	:	PUNCT
admet-942	520	6	implications	implication	NOUN
admet-942	520	7	in	in	ADP
admet-942	520	8	drug	drug	NOUN
admet-942	520	9	discovery	discovery	NOUN
admet-942	520	10	and	and	CCONJ
admet-942	520	11	clinical	clinical	ADJ
admet-942	520	12	applications	application	NOUN
admet-942	520	13	.	.	PUNCT
admet-942	521	1	journal	journal	NOUN
admet-942	521	2	of	of	ADP
admet-942	521	3	cellular	cellular	ADJ
admet-942	521	4	physiology	physiology	NOUN
admet-942	521	5	234	234	NUM
admet-942	521	6	(	(	PUNCT
admet-942	521	7	2019	2019	NUM
admet-942	521	8	)	)	PUNCT
admet-942	521	9	8352	8352	NUM
admet-942	521	10	-	-	SYM
admet-942	521	11	8380	8380	NUM
admet-942	521	12	.	.	PUNCT
admet-942	522	1	https://doi.org/10.1002/jcp.27729	https://doi.org/10.1002/jcp.27729	PROPN
admet-942	522	2	.	.	PUNCT
admet-942	523	1	[	[	X
admet-942	523	2	2	2	NUM
admet-942	523	3	]	]	X
admet-942	523	4	y.a	y.a	PROPN
admet-942	523	5	.	.	PROPN
admet-942	523	6	jodat	jodat	PROPN
admet-942	523	7	,	,	PUNCT
admet-942	523	8	m.g	m.g	PROPN
admet-942	523	9	.	.	PROPN
admet-942	523	10	kang	kang	PROPN
admet-942	523	11	,	,	PUNCT
admet-942	523	12	k.	k.	PROPN
admet-942	523	13	kiaee	kiaee	PROPN
admet-942	523	14	,	,	PUNCT
admet-942	523	15	g.j	g.j	PROPN
admet-942	523	16	.	.	PROPN
admet-942	523	17	kim	kim	PROPN
admet-942	523	18	,	,	PUNCT
admet-942	523	19	a.f.h	a.f.h	PROPN
admet-942	523	20	.	.	PUNCT
admet-942	523	21	martinez	martinez	PROPN
admet-942	523	22	,	,	PUNCT
admet-942	523	23	a.	a.	NOUN
admet-942	523	24	rosenkranz	rosenkranz	PROPN
admet-942	523	25	,	,	PUNCT
admet-942	523	26	h.	h.	PROPN
admet-942	523	27	bae	bae	PROPN
admet-942	523	28	,	,	PUNCT
admet-942	523	29	s.r	s.r	PROPN
admet-942	523	30	.	.	PROPN
admet-942	523	31	shin	shin	PROPN
admet-942	523	32	.	.	PUNCT
admet-942	524	1	humanderived	humanderive	VERB
admet-942	524	2	organ	organ	NOUN
admet-942	524	3	-	-	PUNCT
admet-942	524	4	on	on	ADP
admet-942	524	5	-	-	PUNCT
admet-942	524	6	a	a	DET
admet-942	524	7	-	-	PUNCT
admet-942	524	8	chip	chip	NOUN
admet-942	524	9	for	for	ADP
admet-942	524	10	personalized	personalized	ADJ
admet-942	524	11	drug	drug	NOUN
admet-942	524	12	development	development	NOUN
admet-942	524	13	.	.	PUNCT
admet-942	525	1	current	current	ADJ
admet-942	525	2	pharmaceutical	pharmaceutical	ADJ
admet-942	525	3	design	design	NOUN
admet-942	525	4	24	24	NUM
admet-942	525	5	(	(	PUNCT
admet-942	525	6	2019	2019	NUM
admet-942	525	7	)	)	PUNCT
admet-942	525	8	5471	5471	NUM
admet-942	525	9	-	-	SYM
admet-942	525	10	5486	5486	NUM
admet-942	525	11	.	.	PUNCT
admet-942	526	1	https://doi.org/10.2174/1381612825666190308150055	https://doi.org/10.2174/1381612825666190308150055	VERB
admet-942	526	2	.	.	PUNCT
admet-942	527	1	[	[	X
admet-942	527	2	3	3	NUM
admet-942	527	3	]	]	PUNCT
admet-942	527	4	a.	a.	NOUN
admet-942	527	5	lin	lin	PROPN
admet-942	527	6	,	,	PUNCT
admet-942	527	7	f.	f.	PROPN
admet-942	527	8	sved	sve	VERB
admet-942	527	9	skottvoll	skottvoll	NOUN
admet-942	527	10	,	,	PUNCT
admet-942	527	11	s.	s.	PROPN
admet-942	527	12	rayner	rayner	PROPN
admet-942	527	13	,	,	PUNCT
admet-942	527	14	s.	s.	PROPN
admet-942	527	15	pedersen	pedersen	PROPN
admet-942	527	16	-	-	PUNCT
admet-942	527	17	bjergaard	bjergaard	NOUN
admet-942	527	18	,	,	PUNCT
admet-942	527	19	g.	g.	PROPN
admet-942	527	20	sullivan	sullivan	PROPN
admet-942	527	21	,	,	PUNCT
admet-942	527	22	s.	s.	PROPN
admet-942	527	23	krauss	krauss	PROPN
admet-942	527	24	,	,	PUNCT
admet-942	527	25	s.	s.	PROPN
admet-942	527	26	ray	ray	PROPN
admet-942	527	27	wilson	wilson	PROPN
admet-942	527	28	,	,	PUNCT
admet-942	527	29	s.	s.	PROPN
admet-942	527	30	harrison	harrison	PROPN
admet-942	527	31	.	.	PUNCT
admet-942	528	1	3d	3d	NUM
admet-942	528	2	cell	cell	NOUN
admet-942	528	3	culture	culture	NOUN
admet-942	528	4	models	model	NOUN
admet-942	528	5	and	and	CCONJ
admet-942	528	6	organ	organ	NOUN
admet-942	528	7	-	-	PUNCT
admet-942	528	8	on	on	ADP
admet-942	528	9	-	-	PUNCT
admet-942	528	10	a	a	DET
admet-942	528	11	-	-	PUNCT
admet-942	528	12	chip	chip	NOUN
admet-942	528	13	:	:	PUNCT
admet-942	528	14	meet	meet	VERB
admet-942	528	15	separation	separation	NOUN
admet-942	528	16	science	science	NOUN
admet-942	528	17	and	and	CCONJ
admet-942	528	18	mass	mass	ADJ
admet-942	528	19	spectrometry	spectrometry	NOUN
admet-942	528	20	.	.	PUNCT
admet-942	529	1	electrophoresis	electrophoresis	NOUN
admet-942	529	2	41	41	NUM
admet-942	529	3	(	(	PUNCT
admet-942	529	4	2020	2020	NUM
admet-942	529	5	)	)	PUNCT
admet-942	529	6	56	56	NUM
admet-942	529	7	-	-	SYM
admet-942	529	8	64	64	NUM
admet-942	529	9	.	.	PUNCT
admet-942	530	1	https://doi.org/10.1002/elps.201900170	https://doi.org/10.1002/elps.201900170	NOUN
admet-942	530	2	.	.	PUNCT
admet-942	531	1	[	[	X
admet-942	531	2	4	4	NUM
admet-942	531	3	]	]	X
admet-942	531	4	j.a	j.a	PROPN
admet-942	531	5	.	.	PROPN
admet-942	531	6	kim	kim	PROPN
admet-942	531	7	,	,	PUNCT
admet-942	531	8	s.	s.	PROPN
admet-942	531	9	hong	hong	PROPN
admet-942	531	10	,	,	PUNCT
admet-942	531	11	w.j	w.j	PROPN
admet-942	531	12	.	.	PROPN
admet-942	531	13	rhee	rhee	PROPN
admet-942	531	14	.	.	PUNCT
admet-942	532	1	microfluidic	microfluidic	ADJ
admet-942	532	2	three	three	NUM
admet-942	532	3	-	-	PUNCT
admet-942	532	4	dimensional	dimensional	ADJ
admet-942	532	5	cell	cell	NOUN
admet-942	532	6	culture	culture	NOUN
admet-942	532	7	of	of	ADP
admet-942	532	8	stem	stem	NOUN
admet-942	532	9	cells	cell	NOUN
admet-942	532	10	for	for	ADP
admet-942	532	11	highthroughput	highthroughput	ADJ
admet-942	532	12	analysis	analysis	NOUN
admet-942	532	13	.	.	PUNCT
admet-942	533	1	world	world	PROPN
admet-942	533	2	j	j	PROPN
admet-942	533	3	stem	stem	NOUN
admet-942	533	4	cells	cell	NOUN
admet-942	533	5	11	11	NUM
admet-942	533	6	(	(	PUNCT
admet-942	533	7	2019	2019	NUM
admet-942	533	8	)	)	PUNCT
admet-942	533	9	803	803	NUM
admet-942	533	10	-	-	SYM
admet-942	533	11	816	816	NUM
admet-942	533	12	.	.	PUNCT
admet-942	533	13	https://doi.org/10.4252/wjsc.v11.i10.803	https://doi.org/10.4252/wjsc.v11.i10.803	NOUN
admet-942	533	14	.	.	PUNCT
admet-942	534	1	[	[	X
admet-942	534	2	5	5	NUM
admet-942	534	3	]	]	X
admet-942	534	4	c.c	c.c	PROPN
admet-942	534	5	.	.	PROPN
admet-942	534	6	miranda	miranda	PROPN
admet-942	534	7	,	,	PUNCT
admet-942	534	8	t.g	t.g	PROPN
admet-942	534	9	.	.	PROPN
admet-942	534	10	fernandes	fernandes	PROPN
admet-942	534	11	,	,	PUNCT
admet-942	534	12	m.m	m.m	PROPN
admet-942	534	13	.	.	PROPN
admet-942	534	14	diogo	diogo	PROPN
admet-942	534	15	,	,	PUNCT
admet-942	534	16	j.m.s	j.m.s	PROPN
admet-942	534	17	.	.	PUNCT
admet-942	535	1	cabral	cabral	PROPN
admet-942	535	2	.	.	PROPN
admet-942	536	1	towards	towards	ADP
admet-942	536	2	multi	multi	ADJ
admet-942	536	3	-	-	ADJ
admet-942	536	4	organoid	organoid	ADJ
admet-942	536	5	systems	system	NOUN
admet-942	536	6	for	for	ADP
admet-942	536	7	drug	drug	NOUN
admet-942	536	8	screening	screening	NOUN
admet-942	536	9	applications	application	NOUN
admet-942	536	10	.	.	PUNCT
admet-942	537	1	bioengineering	bioengineere	VERB
admet-942	537	2	5	5	NUM
admet-942	537	3	(	(	PUNCT
admet-942	537	4	2018	2018	NUM
admet-942	537	5	)	)	PUNCT
admet-942	537	6	1	1	NUM
admet-942	537	7	-	-	SYM
admet-942	537	8	17	17	NUM
admet-942	537	9	.	.	PUNCT
admet-942	538	1	https://doi.org/10.3390/bioengineering5030049	https://doi.org/10.3390/bioengineering5030049	PROPN
admet-942	538	2	.	.	PUNCT
admet-942	539	1	[	[	X
admet-942	539	2	6	6	NUM
admet-942	539	3	]	]	PUNCT
admet-942	539	4	t.	t.	PROPN
admet-942	539	5	meyer	meyer	PROPN
admet-942	539	6	,	,	PUNCT
admet-942	539	7	m.	m.	NOUN
admet-942	539	8	tiburcy	tiburcy	PROPN
admet-942	539	9	,	,	PUNCT
admet-942	539	10	w.h	w.h	PROPN
admet-942	539	11	.	.	PROPN
admet-942	539	12	zimmermann	zimmermann	PROPN
admet-942	539	13	.	.	PUNCT
admet-942	540	1	cardiac	cardiac	ADJ
admet-942	540	2	macrotissues	macrotissue	NOUN
admet-942	540	3	-	-	PUNCT
admet-942	540	4	on	on	ADP
admet-942	540	5	-	-	PUNCT
admet-942	540	6	a	a	DET
admet-942	540	7	-	-	PUNCT
admet-942	540	8	plate	plate	NOUN
admet-942	540	9	models	model	NOUN
admet-942	540	10	for	for	ADP
admet-942	540	11	phenotypic	phenotypic	ADJ
admet-942	540	12	drug	drug	NOUN
admet-942	540	13	screens	screen	NOUN
admet-942	540	14	.	.	PUNCT
admet-942	541	1	advanced	advanced	ADJ
admet-942	541	2	drug	drug	NOUN
admet-942	541	3	delivery	delivery	NOUN
admet-942	541	4	reviews	review	NOUN
admet-942	541	5	140	140	NUM
admet-942	541	6	(	(	PUNCT
admet-942	541	7	2019	2019	NUM
admet-942	541	8	)	)	PUNCT
admet-942	541	9	93	93	NUM
admet-942	541	10	-	-	SYM
admet-942	541	11	100	100	NUM
admet-942	541	12	.	.	PUNCT
admet-942	542	1	https://doi.org/10.1016/j.addr.2019.03.002	https://doi.org/10.1016/j.addr.2019.03.002	NOUN
admet-942	542	2	.	.	PUNCT
admet-942	543	1	[	[	X
admet-942	543	2	7	7	X
admet-942	543	3	]	]	PUNCT
admet-942	543	4	b.	b.	PROPN
admet-942	543	5	zhang	zhang	PROPN
admet-942	543	6	,	,	PUNCT
admet-942	543	7	a.	a.	NOUN
admet-942	543	8	korolj	korolj	PROPN
admet-942	543	9	,	,	PUNCT
admet-942	543	10	b.f.l	b.f.l	PROPN
admet-942	543	11	.	.	PUNCT
admet-942	544	1	lai	lai	PROPN
admet-942	544	2	,	,	PUNCT
admet-942	544	3	m.	m.	NOUN
admet-942	544	4	radisic	radisic	NOUN
admet-942	544	5	.	.	PUNCT
admet-942	545	1	advances	advance	NOUN
admet-942	545	2	in	in	ADP
admet-942	545	3	organ	organ	NOUN
admet-942	545	4	-	-	PUNCT
admet-942	545	5	on	on	ADP
admet-942	545	6	-	-	PUNCT
admet-942	545	7	a	a	DET
admet-942	545	8	-	-	PUNCT
admet-942	545	9	chip	chip	NOUN
admet-942	545	10	engineering	engineering	NOUN
admet-942	545	11	.	.	PUNCT
admet-942	546	1	nature	nature	NOUN
admet-942	546	2	reviews	review	VERB
admet-942	546	3	materials	material	NOUN
admet-942	546	4	3	3	NUM
admet-942	546	5	(	(	PUNCT
admet-942	546	6	2018	2018	NUM
admet-942	546	7	)	)	PUNCT
admet-942	546	8	257	257	NUM
admet-942	546	9	-	-	SYM
admet-942	546	10	278	278	NUM
admet-942	546	11	.	.	PUNCT
admet-942	547	1	https://doi.org/10.1038/s41578-018-0034-7	https://doi.org/10.1038/s41578-018-0034-7	NUM
admet-942	547	2	.	.	PUNCT
admet-942	548	1	[	[	X
admet-942	548	2	8	8	NUM
admet-942	548	3	]	]	X
admet-942	548	4	l.h.m	l.h.m	NOUN
admet-942	548	5	.	.	PUNCT
admet-942	549	1	van	van	PROPN
admet-942	549	2	de	de	PROPN
admet-942	549	3	burgwal	burgwal	PROPN
admet-942	549	4	,	,	PUNCT
admet-942	549	5	p.	p.	PROPN
admet-942	549	6	van	van	PROPN
admet-942	549	7	dorst	dorst	PROPN
admet-942	549	8	,	,	PUNCT
admet-942	549	9	h.	h.	PROPN
admet-942	549	10	viëtor	viëtor	PROPN
admet-942	549	11	,	,	PUNCT
admet-942	549	12	r.	r.	PROPN
admet-942	549	13	luttge	luttge	PROPN
admet-942	549	14	,	,	PUNCT
admet-942	549	15	e.	e.	PROPN
admet-942	549	16	claassen	claassen	PROPN
admet-942	549	17	.	.	PUNCT
admet-942	550	1	hybrid	hybrid	ADJ
admet-942	550	2	business	business	NOUN
admet-942	550	3	models	model	NOUN
admet-942	550	4	for	for	ADP
admet-942	550	5	‘	'	PUNCT
admet-942	550	6	organ	organ	VERB
admet-942	550	7	-	-	PUNCT
admet-942	550	8	on	on	ADP
admet-942	550	9	-	-	PUNCT
admet-942	550	10	a	a	DET
admet-942	550	11	-	-	PUNCT
admet-942	550	12	chip	chip	NOUN
admet-942	550	13	’	'	PUNCT
admet-942	550	14	technology	technology	NOUN
admet-942	550	15	:	:	PUNCT
admet-942	550	16	the	the	DET
admet-942	550	17	best	good	ADJ
admet-942	550	18	of	of	ADP
admet-942	550	19	both	both	DET
admet-942	550	20	worlds	world	NOUN
admet-942	550	21	.	.	PUNCT
admet-942	551	1	pharmanutrition	pharmanutrition	NOUN
admet-942	551	2	6	6	NUM
admet-942	551	3	(	(	PUNCT
admet-942	551	4	2018	2018	NUM
admet-942	551	5	)	)	PUNCT
admet-942	551	6	55	55	NUM
admet-942	551	7	-	-	SYM
admet-942	551	8	63	63	NUM
admet-942	551	9	.	.	PUNCT
admet-942	552	1	https://doi.org/10.1016/j.phanu.2018.02.001	https://doi.org/10.1016/j.phanu.2018.02.001	NOUN
admet-942	552	2	.	.	PUNCT
admet-942	553	1	[	[	X
admet-942	553	2	9	9	NUM
admet-942	553	3	]	]	X
admet-942	553	4	n.	n.	PROPN
admet-942	553	5	franzen	franzen	PROPN
admet-942	553	6	,	,	PUNCT
admet-942	553	7	w.h	w.h	PROPN
admet-942	553	8	.	.	PROPN
admet-942	553	9	van	van	PROPN
admet-942	553	10	harten	harten	PROPN
admet-942	553	11	,	,	PUNCT
admet-942	553	12	v.p	v.p	PROPN
admet-942	553	13	.	.	PROPN
admet-942	553	14	retèl	retèl	PROPN
admet-942	553	15	,	,	PUNCT
admet-942	553	16	p.	p.	PROPN
admet-942	553	17	loskill	loskill	PROPN
admet-942	553	18	,	,	PUNCT
admet-942	553	19	j.	j.	PROPN
admet-942	553	20	van	van	PROPN
admet-942	553	21	den	den	PROPN
admet-942	553	22	eijnden	eijnden	PROPN
admet-942	553	23	-	-	PUNCT
admet-942	553	24	van	van	NOUN
admet-942	553	25	raaij	raaij	NOUN
admet-942	553	26	,	,	PUNCT
admet-942	553	27	m.	m.	PROPN
admet-942	553	28	ijzerman	ijzerman	PROPN
admet-942	553	29	.	.	PUNCT
admet-942	553	30	impact	impact	NOUN
admet-942	553	31	of	of	ADP
admet-942	553	32	organ	organ	NOUN
admet-942	553	33	-	-	PUNCT
admet-942	553	34	on	on	ADP
admet-942	553	35	-	-	PUNCT
admet-942	553	36	a	a	DET
admet-942	553	37	-	-	PUNCT
admet-942	553	38	chip	chip	NOUN
admet-942	553	39	technology	technology	NOUN
admet-942	553	40	on	on	ADP
admet-942	553	41	pharmaceutical	pharmaceutical	ADJ
admet-942	553	42	r&d	r&d	NOUN
admet-942	553	43	costs	cost	NOUN
admet-942	553	44	.	.	PUNCT
admet-942	554	1	drug	drug	NOUN
admet-942	554	2	discovery	discovery	PROPN
admet-942	554	3	today	today	NOUN
admet-942	554	4	24	24	NUM
admet-942	554	5	(	(	PUNCT
admet-942	554	6	2019	2019	NUM
admet-942	554	7	)	)	PUNCT
admet-942	554	8	17201724	17201724	NUM
admet-942	554	9	.	.	PUNCT
admet-942	555	1	https://doi.org/10.1016/j.drudis.2019.06.003	https://doi.org/10.1016/j.drudis.2019.06.003	VERB
admet-942	555	2	.	.	PUNCT
admet-942	556	1	[	[	X
admet-942	556	2	10	10	NUM
admet-942	556	3	]	]	X
admet-942	556	4	s.a.p	s.a.p	NOUN
admet-942	556	5	.	.	PUNCT
admet-942	556	6	rajan	rajan	PROPN
admet-942	556	7	,	,	PUNCT
admet-942	556	8	j.	j.	PROPN
admet-942	556	9	aleman	aleman	PROPN
admet-942	556	10	,	,	PUNCT
admet-942	556	11	m.m	m.m	PROPN
admet-942	556	12	.	.	PROPN
admet-942	556	13	wan	wan	PROPN
admet-942	556	14	,	,	PUNCT
admet-942	556	15	n.	n.	PROPN
admet-942	556	16	pourhabibi	pourhabibi	PROPN
admet-942	556	17	zarandi	zarandi	PROPN
admet-942	556	18	,	,	PUNCT
admet-942	556	19	g.	g.	PROPN
admet-942	556	20	nzou	nzou	PROPN
admet-942	556	21	,	,	PUNCT
admet-942	556	22	s.	s.	PROPN
admet-942	556	23	murphy	murphy	PROPN
admet-942	556	24	,	,	PUNCT
admet-942	556	25	c.e	c.e	PROPN
admet-942	556	26	.	.	PROPN
admet-942	556	27	bishop	bishop	PROPN
admet-942	556	28	,	,	PUNCT
admet-942	556	29	h.	h.	PROPN
admet-942	556	30	sadriardekani	sadriardekani	PROPN
admet-942	556	31	,	,	PUNCT
admet-942	556	32	t.	t.	PROPN
admet-942	556	33	shupe	shupe	PROPN
admet-942	556	34	,	,	PUNCT
admet-942	556	35	a.	a.	PROPN
admet-942	556	36	atala	atala	PROPN
admet-942	556	37	,	,	PUNCT
admet-942	556	38	a.r	a.r	PROPN
admet-942	556	39	.	.	PROPN
admet-942	556	40	hall	hall	PROPN
admet-942	556	41	,	,	PUNCT
admet-942	556	42	a.	a.	NOUN
admet-942	556	43	skardal	skardal	NOUN
admet-942	556	44	.	.	PUNCT
admet-942	557	1	probing	probe	VERB
admet-942	557	2	prodrug	prodrug	NOUN
admet-942	557	3	metabolism	metabolism	NOUN
admet-942	557	4	and	and	CCONJ
admet-942	557	5	reciprocal	reciprocal	ADJ
admet-942	557	6	toxicity	toxicity	NOUN
admet-942	557	7	with	with	ADP
admet-942	557	8	an	an	DET
admet-942	557	9	integrated	integrate	VERB
admet-942	557	10	and	and	CCONJ
admet-942	557	11	humanized	humanize	VERB
admet-942	557	12	multi	multi	ADJ
admet-942	557	13	-	-	ADJ
admet-942	557	14	tissue	tissue	ADJ
admet-942	557	15	organ	organ	NOUN
admet-942	557	16	-	-	PUNCT
admet-942	557	17	on	on	ADP
admet-942	557	18	-	-	PUNCT
admet-942	557	19	a	a	DET
admet-942	557	20	-	-	PUNCT
admet-942	557	21	chip	chip	NOUN
admet-942	557	22	platform	platform	NOUN
admet-942	557	23	.	.	PUNCT
admet-942	558	1	acta	acta	PROPN
admet-942	558	2	biomaterialia	biomaterialia	PROPN
admet-942	558	3	106	106	NUM
admet-942	558	4	(	(	PUNCT
admet-942	558	5	2020	2020	NUM
admet-942	558	6	)	)	PUNCT
admet-942	558	7	124	124	NUM
admet-942	558	8	-	-	SYM
admet-942	558	9	135	135	NUM
admet-942	558	10	.	.	PUNCT
admet-942	559	1	https://doi.org/10.1016/j.actbio.2020.02.015	https://doi.org/10.1016/j.actbio.2020.02.015	PROPN
admet-942	559	2	.	.	PUNCT
admet-942	560	1	[	[	X
admet-942	560	2	11	11	NUM
admet-942	560	3	]	]	PUNCT
admet-942	560	4	c.	c.	PROPN
admet-942	560	5	oleaga	oleaga	PROPN
admet-942	560	6	,	,	PUNCT
admet-942	560	7	a.	a.	PROPN
admet-942	560	8	riu	riu	PROPN
admet-942	560	9	,	,	PUNCT
admet-942	560	10	s.	s.	PROPN
admet-942	560	11	rothemund	rothemund	PROPN
admet-942	560	12	,	,	PUNCT
admet-942	560	13	a.	a.	NOUN
admet-942	560	14	lavado	lavado	PROPN
admet-942	560	15	,	,	PUNCT
admet-942	560	16	c.w	c.w	PROPN
admet-942	560	17	.	.	PROPN
admet-942	560	18	mcaleer	mcaleer	PROPN
admet-942	560	19	,	,	PUNCT
admet-942	560	20	c.j	c.j	PROPN
admet-942	560	21	.	.	PROPN
admet-942	560	22	long	long	PROPN
admet-942	560	23	,	,	PUNCT
admet-942	560	24	k.	k.	PROPN
admet-942	560	25	persaud	persaud	PROPN
admet-942	560	26	,	,	PUNCT
admet-942	560	27	n.s	n.s	PROPN
admet-942	560	28	.	.	PROPN
admet-942	560	29	narasimhan	narasimhan	PROPN
admet-942	560	30	,	,	PUNCT
admet-942	560	31	m.	m.	NOUN
admet-942	560	32	tran	tran	PROPN
admet-942	560	33	,	,	PUNCT
admet-942	560	34	j.	j.	PROPN
admet-942	560	35	roles	roles	PROPN
admet-942	560	36	,	,	PUNCT
admet-942	560	37	c.a	c.a	PROPN
admet-942	560	38	.	.	PROPN
admet-942	560	39	carmona	carmona	PROPN
admet-942	560	40	-	-	PUNCT
admet-942	560	41	moran	moran	PROPN
admet-942	560	42	,	,	PUNCT
admet-942	560	43	t.	t.	PROPN
admet-942	560	44	sasserath	sasserath	PROPN
admet-942	560	45	,	,	PUNCT
admet-942	560	46	d.h	d.h	PROPN
admet-942	560	47	.	.	PROPN
admet-942	560	48	elbrecht	elbrecht	PROPN
admet-942	560	49	,	,	PUNCT
admet-942	560	50	l.	l.	PROPN
admet-942	560	51	kumanchik	kumanchik	PROPN
admet-942	560	52	,	,	PUNCT
admet-942	560	53	l.r	l.r	PROPN
admet-942	560	54	.	.	PROPN
admet-942	560	55	bridges	bridge	NOUN
admet-942	560	56	,	,	PUNCT
admet-942	560	57	c.	c.	PROPN
admet-942	560	58	martin	martin	PROPN
admet-942	560	59	,	,	PUNCT
admet-942	560	60	m.t	m.t	PROPN
admet-942	560	61	.	.	PROPN
admet-942	560	62	schnepper	schnepper	PROPN
admet-942	560	63	,	,	PUNCT
admet-942	560	64	g.	g.	PROPN
admet-942	560	65	ekman	ekman	PROPN
admet-942	560	66	,	,	PUNCT
admet-942	560	67	m.	m.	PROPN
admet-942	560	68	jackson	jackson	PROPN
admet-942	560	69	,	,	PUNCT
admet-942	560	70	y.i	y.i	PROPN
admet-942	560	71	.	.	PROPN
admet-942	560	72	wang	wang	PROPN
admet-942	560	73	,	,	PUNCT
admet-942	560	74	r.	r.	PROPN
admet-942	560	75	note	note	PROPN
admet-942	560	76	,	,	PUNCT
admet-942	560	77	j.	j.	PROPN
admet-942	560	78	langer	langer	PROPN
admet-942	560	79	,	,	PUNCT
admet-942	560	80	s.	s.	PROPN
admet-942	560	81	teissier	teissier	PROPN
admet-942	560	82	,	,	PUNCT
admet-942	560	83	j.j	j.j	PROPN
admet-942	560	84	.	.	PROPN
admet-942	560	85	hickman	hickman	PROPN
admet-942	560	86	.	.	PUNCT
admet-942	561	1	investigation	investigation	NOUN
admet-942	561	2	of	of	ADP
admet-942	561	3	the	the	DET
admet-942	561	4	effect	effect	NOUN
admet-942	561	5	of	of	ADP
admet-942	561	6	hepatic	hepatic	ADJ
admet-942	561	7	metabolism	metabolism	NOUN
admet-942	561	8	on	on	ADP
admet-942	561	9	off	off	ADP
admet-942	561	10	-	-	PUNCT
admet-942	561	11	target	target	NOUN
admet-942	561	12	cardiotoxicity	cardiotoxicity	NOUN
admet-942	561	13	in	in	ADP
admet-942	561	14	a	a	DET
admet-942	561	15	multi	multi	ADJ
admet-942	561	16	-	-	ADJ
admet-942	561	17	organ	organ	ADJ
admet-942	561	18	humanhttps://doi.org/10.1002/jcp.27729	humanhttps://doi.org/10.1002/jcp.27729	PROPN
admet-942	561	19	https://doi.org/10.2174/1381612825666190308150055	https://doi.org/10.2174/1381612825666190308150055	PROPN
admet-942	561	20	https://doi.org/10.1002/elps.201900170	https://doi.org/10.1002/elps.201900170	ADP
admet-942	561	21	https://doi.org/10.4252/wjsc.v11.i10.803	https://doi.org/10.4252/wjsc.v11.i10.803	NOUN
admet-942	561	22	https://doi.org/10.1038/s41578-018-0034-7	https://doi.org/10.1038/s41578-018-0034-7	NUM
admet-942	561	23	https://doi.org/10.1016/j.phanu.2018.02.001	https://doi.org/10.1016/j.phanu.2018.02.001	PROPN
admet-942	561	24	https://doi.org/10.1016/j.drudis.2019.06.003	https://doi.org/10.1016/j.drudis.2019.06.003	NUM
admet-942	561	25	https://doi.org/10.1016/j.actbio.2020.02.015	https://doi.org/10.1016/j.actbio.2020.02.015	PROPN
admet-942	561	26	admet	admet	PROPN
admet-942	561	27	&	&	CCONJ
admet-942	561	28	dmpk	dmpk	PROPN
admet-942	561	29	9(2	9(2	NUM
admet-942	561	30	)	)	PUNCT
admet-942	561	31	(	(	PUNCT
admet-942	561	32	2021	2021	NUM
admet-942	561	33	)	)	PUNCT
admet-942	561	34	111	111	NUM
admet-942	561	35	-	-	SYM
admet-942	561	36	141	141	NUM
admet-942	561	37	organ	organ	NOUN
admet-942	561	38	-	-	PUNCT
admet-942	561	39	on	on	ADP
admet-942	561	40	-	-	PUNCT
admet-942	561	41	a	a	DET
admet-942	561	42	-	-	PUNCT
admet-942	561	43	chip	chip	NOUN
admet-942	561	44	systems	system	NOUN
admet-942	561	45	for	for	ADP
admet-942	561	46	new	new	ADJ
admet-942	561	47	drugs	drug	NOUN
admet-942	561	48	development	development	NOUN
admet-942	561	49	doi	doi	PROPN
admet-942	561	50	:	:	PUNCT
admet-942	561	51	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	561	52	133	133	NUM
admet-942	561	53	on	on	ADP
admet-942	561	54	-	-	PUNCT
admet-942	561	55	a	a	DET
admet-942	561	56	-	-	PUNCT
admet-942	561	57	chip	chip	NOUN
admet-942	561	58	system	system	NOUN
admet-942	561	59	.	.	PUNCT
admet-942	562	1	biomaterials	biomaterial	NOUN
admet-942	562	2	182	182	NUM
admet-942	562	3	(	(	PUNCT
admet-942	562	4	2018	2018	NUM
admet-942	562	5	)	)	PUNCT
admet-942	562	6	176	176	NUM
admet-942	562	7	-	-	SYM
admet-942	562	8	190	190	NUM
admet-942	562	9	.	.	PUNCT
admet-942	563	1	https://doi.org/10.1016/j.biomaterials.2018.07.062	https://doi.org/10.1016/j.biomaterials.2018.07.062	PROPN
admet-942	563	2	.	.	PUNCT
admet-942	564	1	[	[	X
admet-942	564	2	12	12	NUM
admet-942	564	3	]	]	PUNCT
admet-942	564	4	k.	k.	PROPN
admet-942	564	5	viravaidya	viravaidya	PROPN
admet-942	564	6	,	,	PUNCT
admet-942	564	7	a.	a.	NOUN
admet-942	564	8	sin	sin	NOUN
admet-942	564	9	,	,	PUNCT
admet-942	564	10	m.l	m.l	PROPN
admet-942	564	11	.	.	PROPN
admet-942	564	12	shuler	shuler	PROPN
admet-942	564	13	.	.	PUNCT
admet-942	565	1	development	development	NOUN
admet-942	565	2	of	of	ADP
admet-942	565	3	a	a	DET
admet-942	565	4	microscale	microscale	ADJ
admet-942	565	5	cell	cell	NOUN
admet-942	565	6	culture	culture	NOUN
admet-942	565	7	analog	analog	NOUN
admet-942	565	8	to	to	PART
admet-942	565	9	probe	probe	VERB
admet-942	565	10	naphthalene	naphthalene	NOUN
admet-942	565	11	toxicity	toxicity	NOUN
admet-942	565	12	.	.	PUNCT
admet-942	566	1	biotechnology	biotechnology	NOUN
admet-942	566	2	progress	progress	VERB
admet-942	566	3	20	20	NUM
admet-942	566	4	(	(	PUNCT
admet-942	566	5	2004	2004	NUM
admet-942	566	6	)	)	PUNCT
admet-942	566	7	316	316	NUM
admet-942	566	8	-	-	SYM
admet-942	566	9	323	323	NUM
admet-942	566	10	.	.	PUNCT
admet-942	567	1	https://doi.org/10.1021/bp0341996	https://doi.org/10.1021/bp0341996	X
admet-942	567	2	.	.	PUNCT
admet-942	568	1	[	[	X
admet-942	568	2	13	13	NUM
admet-942	568	3	]	]	PUNCT
admet-942	568	4	k.	k.	PROPN
admet-942	568	5	ronaldson	ronaldson	PROPN
admet-942	568	6	-	-	PUNCT
admet-942	568	7	bouchard	bouchard	PROPN
admet-942	568	8	,	,	PUNCT
admet-942	568	9	g.	g.	PROPN
admet-942	568	10	vunjak	vunjak	PROPN
admet-942	568	11	-	-	PUNCT
admet-942	568	12	novakovic	novakovic	ADJ
admet-942	568	13	.	.	PUNCT
admet-942	569	1	organs	organ	NOUN
admet-942	569	2	-	-	PUNCT
admet-942	569	3	on	on	ADP
admet-942	569	4	-	-	PUNCT
admet-942	569	5	a	a	DET
admet-942	569	6	-	-	PUNCT
admet-942	569	7	chip	chip	NOUN
admet-942	569	8	:	:	PUNCT
admet-942	569	9	a	a	DET
admet-942	569	10	fast	fast	ADJ
admet-942	569	11	track	track	NOUN
admet-942	569	12	for	for	ADP
admet-942	569	13	engineered	engineer	VERB
admet-942	569	14	human	human	ADJ
admet-942	569	15	tissues	tissue	NOUN
admet-942	569	16	in	in	ADP
admet-942	569	17	drug	drug	NOUN
admet-942	569	18	development	development	NOUN
admet-942	569	19	.	.	PUNCT
admet-942	570	1	cell	cell	NOUN
admet-942	570	2	stem	stem	NOUN
admet-942	570	3	cell	cell	NOUN
admet-942	570	4	22	22	NUM
admet-942	570	5	(	(	PUNCT
admet-942	570	6	2018	2018	NUM
admet-942	570	7	)	)	PUNCT
admet-942	570	8	310	310	NUM
admet-942	570	9	-	-	SYM
admet-942	570	10	324	324	NUM
admet-942	570	11	.	.	PUNCT
admet-942	571	1	https://doi.org/10.1016/j.stem.2018.02.011	https://doi.org/10.1016/j.stem.2018.02.011	X
admet-942	571	2	.	.	PUNCT
admet-942	572	1	[	[	X
admet-942	572	2	14	14	NUM
admet-942	572	3	]	]	X
admet-942	572	4	j.w	j.w	PROPN
admet-942	572	5	.	.	PUNCT
admet-942	572	6	choi	choi	PROPN
admet-942	572	7	,	,	PUNCT
admet-942	572	8	s.-y	s.-y	NOUN
admet-942	572	9	.	.	PUNCT
admet-942	573	1	lee	lee	PROPN
admet-942	573	2	,	,	PUNCT
admet-942	573	3	d.w	d.w	PROPN
admet-942	573	4	.	.	PROPN
admet-942	573	5	lee	lee	PROPN
admet-942	573	6	.	.	PUNCT
admet-942	574	1	a	a	DET
admet-942	574	2	cancer	cancer	NOUN
admet-942	574	3	spheroid	spheroid	NOUN
admet-942	574	4	array	array	VERB
admet-942	574	5	chip	chip	NOUN
admet-942	574	6	for	for	ADP
admet-942	574	7	selecting	select	VERB
admet-942	574	8	effective	effective	ADJ
admet-942	574	9	drug	drug	NOUN
admet-942	574	10	.	.	PUNCT
admet-942	575	1	micromachines	micromachine	NOUN
admet-942	575	2	10	10	NUM
admet-942	575	3	(	(	PUNCT
admet-942	575	4	2019	2019	NUM
admet-942	575	5	)	)	PUNCT
admet-942	575	6	688	688	NUM
admet-942	575	7	.	.	PUNCT
admet-942	576	1	https://doi.org/10.3390/mi10100688	https://doi.org/10.3390/mi10100688	X
admet-942	576	2	.	.	PUNCT
admet-942	577	1	[	[	X
admet-942	577	2	15	15	NUM
admet-942	577	3	]	]	X
admet-942	577	4	w.	w.	PROPN
admet-942	577	5	liu	liu	PROPN
admet-942	577	6	,	,	PUNCT
admet-942	577	7	j.	j.	PROPN
admet-942	577	8	song	song	PROPN
admet-942	577	9	,	,	PUNCT
admet-942	577	10	x.	x.	NOUN
admet-942	577	11	du	du	PROPN
admet-942	577	12	,	,	PUNCT
admet-942	577	13	y.	y.	PROPN
admet-942	577	14	zhou	zhou	PROPN
admet-942	577	15	,	,	PUNCT
admet-942	577	16	y.	y.	PROPN
admet-942	577	17	li	li	PROPN
admet-942	577	18	,	,	PUNCT
admet-942	577	19	r.	r.	PROPN
admet-942	577	20	li	li	PROPN
admet-942	577	21	,	,	PUNCT
admet-942	577	22	l.	l.	PROPN
admet-942	577	23	lyu	lyu	PROPN
admet-942	577	24	,	,	PUNCT
admet-942	577	25	y.	y.	PROPN
admet-942	577	26	he	he	PRON
admet-942	577	27	,	,	PUNCT
admet-942	577	28	j.	j.	PROPN
admet-942	577	29	hao	hao	PROPN
admet-942	577	30	,	,	PUNCT
admet-942	577	31	j.	j.	PROPN
admet-942	577	32	ben	ben	PROPN
admet-942	577	33	,	,	PUNCT
admet-942	577	34	w.	w.	PROPN
admet-942	577	35	wang	wang	PROPN
admet-942	577	36	,	,	PUNCT
admet-942	577	37	h.	h.	PROPN
admet-942	577	38	shi	shi	PROPN
admet-942	577	39	,	,	PUNCT
admet-942	577	40	q.	q.	PROPN
admet-942	577	41	wang	wang	PROPN
admet-942	577	42	.	.	PUNCT
admet-942	578	1	akr1b10	akr1b10	PROPN
admet-942	578	2	(	(	PUNCT
admet-942	578	3	aldo	aldo	PROPN
admet-942	578	4	-	-	PUNCT
admet-942	578	5	keto	keto	NOUN
admet-942	578	6	reductase	reductase	NOUN
admet-942	578	7	family	family	NOUN
admet-942	578	8	1	1	NUM
admet-942	578	9	b10	b10	PROPN
admet-942	578	10	)	)	PUNCT
admet-942	578	11	promotes	promote	VERB
admet-942	578	12	brain	brain	NOUN
admet-942	578	13	metastasis	metastasis	NOUN
admet-942	578	14	of	of	ADP
admet-942	578	15	lung	lung	NOUN
admet-942	578	16	cancer	cancer	NOUN
admet-942	578	17	cells	cell	NOUN
admet-942	578	18	in	in	ADP
admet-942	578	19	a	a	DET
admet-942	578	20	multi	multi	ADJ
admet-942	578	21	-	-	ADJ
admet-942	578	22	organ	organ	ADJ
admet-942	578	23	microfluidic	microfluidic	ADJ
admet-942	578	24	chip	chip	NOUN
admet-942	578	25	model	model	NOUN
admet-942	578	26	.	.	PUNCT
admet-942	579	1	acta	acta	PROPN
admet-942	579	2	biomaterialia	biomaterialia	PROPN
admet-942	579	3	91	91	NUM
admet-942	579	4	(	(	PUNCT
admet-942	579	5	2019	2019	NUM
admet-942	579	6	)	)	PUNCT
admet-942	579	7	195	195	NUM
admet-942	579	8	-	-	SYM
admet-942	579	9	208	208	NUM
admet-942	579	10	.	.	PUNCT
admet-942	580	1	https://doi.org/10.1016/j.actbio.2019.04.053	https://doi.org/10.1016/j.actbio.2019.04.053	NOUN
admet-942	580	2	.	.	PUNCT
admet-942	581	1	[	[	X
admet-942	581	2	16	16	X
admet-942	581	3	]	]	X
admet-942	581	4	v.	v.	PROPN
admet-942	581	5	monteil	monteil	PROPN
admet-942	581	6	,	,	PUNCT
admet-942	581	7	h.	h.	PROPN
admet-942	581	8	kwon	kwon	PROPN
admet-942	581	9	,	,	PUNCT
admet-942	581	10	p.	p.	PROPN
admet-942	581	11	prado	prado	PROPN
admet-942	581	12	,	,	PUNCT
admet-942	581	13	a.	a.	NOUN
admet-942	581	14	hagelkrüys	hagelkrüys	PROPN
admet-942	581	15	,	,	PUNCT
admet-942	581	16	r.a	r.a	PROPN
admet-942	581	17	.	.	PROPN
admet-942	581	18	wimmer	wimmer	PROPN
admet-942	581	19	,	,	PUNCT
admet-942	581	20	m.	m.	PROPN
admet-942	581	21	stahl	stahl	PROPN
admet-942	581	22	,	,	PUNCT
admet-942	581	23	a.	a.	NOUN
admet-942	581	24	leopoldi	leopoldi	PROPN
admet-942	581	25	,	,	PUNCT
admet-942	581	26	e.	e.	PROPN
admet-942	581	27	garreta	garreta	PROPN
admet-942	581	28	,	,	PUNCT
admet-942	581	29	c.	c.	PROPN
admet-942	581	30	hurtado	hurtado	PROPN
admet-942	581	31	del	del	PROPN
admet-942	581	32	pozo	pozo	PROPN
admet-942	581	33	,	,	PUNCT
admet-942	581	34	f.	f.	PROPN
admet-942	581	35	prosper	prosper	PROPN
admet-942	581	36	,	,	PUNCT
admet-942	581	37	j.p	j.p	PROPN
admet-942	581	38	.	.	PROPN
admet-942	581	39	romero	romero	PROPN
admet-942	581	40	,	,	PUNCT
admet-942	581	41	g.	g.	PROPN
admet-942	581	42	wirnsberger	wirnsberger	PROPN
admet-942	581	43	,	,	PUNCT
admet-942	581	44	h.	h.	PROPN
admet-942	581	45	zhang	zhang	PROPN
admet-942	581	46	,	,	PUNCT
admet-942	581	47	a.s	a.s	PROPN
admet-942	581	48	.	.	PROPN
admet-942	581	49	slutsky	slutsky	PROPN
admet-942	581	50	,	,	PUNCT
admet-942	581	51	r.	r.	PROPN
admet-942	581	52	conder	conder	PROPN
admet-942	581	53	,	,	PUNCT
admet-942	581	54	n.	n.	PROPN
admet-942	581	55	montserrat	montserrat	PROPN
admet-942	581	56	,	,	PUNCT
admet-942	581	57	a.	a.	PROPN
admet-942	581	58	mirazimi	mirazimi	PROPN
admet-942	581	59	,	,	PUNCT
admet-942	581	60	j.m	j.m	PROPN
admet-942	581	61	.	.	PROPN
admet-942	581	62	penninger	penninger	NOUN
admet-942	581	63	.	.	PUNCT
admet-942	582	1	inhibition	inhibition	NOUN
admet-942	582	2	of	of	ADP
admet-942	582	3	sars	sar	NOUN
admet-942	582	4	-	-	PUNCT
admet-942	582	5	cov-2	cov-2	NOUN
admet-942	582	6	infections	infection	NOUN
admet-942	582	7	in	in	ADP
admet-942	582	8	engineered	engineer	VERB
admet-942	582	9	human	human	ADJ
admet-942	582	10	tissues	tissue	NOUN
admet-942	582	11	using	use	VERB
admet-942	582	12	clinical	clinical	ADJ
admet-942	582	13	-	-	PUNCT
admet-942	582	14	grade	grade	NOUN
admet-942	582	15	soluble	soluble	ADJ
admet-942	582	16	human	human	ADJ
admet-942	582	17	ace2	ace2	NOUN
admet-942	582	18	.	.	PUNCT
admet-942	583	1	cell	cell	NOUN
admet-942	583	2	181	181	NUM
admet-942	583	3	(	(	PUNCT
admet-942	583	4	2020	2020	NUM
admet-942	583	5	)	)	PUNCT
admet-942	583	6	905	905	NUM
admet-942	583	7	-	-	PUNCT
admet-942	583	8	913.e7	913.e7	PROPN
admet-942	583	9	.	.	PUNCT
admet-942	583	10	https://doi.org/10.1016/j.cell.2020.04.004	https://doi.org/10.1016/j.cell.2020.04.004	PROPN
admet-942	583	11	.	.	PUNCT
admet-942	584	1	[	[	X
admet-942	584	2	17	17	NUM
admet-942	584	3	]	]	PUNCT
admet-942	584	4	b.	b.	PROPN
admet-942	584	5	zhang	zhang	PROPN
admet-942	584	6	,	,	PUNCT
admet-942	584	7	m.	m.	NOUN
admet-942	584	8	radisic	radisic	NOUN
admet-942	584	9	.	.	PUNCT
admet-942	585	1	organ	organ	NOUN
admet-942	585	2	-	-	PUNCT
admet-942	585	3	on	on	ADP
admet-942	585	4	-	-	PUNCT
admet-942	585	5	a	a	DET
admet-942	585	6	-	-	PUNCT
admet-942	585	7	chip	chip	NOUN
admet-942	585	8	devices	device	NOUN
admet-942	585	9	advance	advance	VERB
admet-942	585	10	to	to	ADP
admet-942	585	11	market	market	NOUN
admet-942	585	12	.	.	PUNCT
admet-942	586	1	lab	lab	NOUN
admet-942	586	2	on	on	ADP
admet-942	586	3	a	a	DET
admet-942	586	4	chip	chip	NOUN
admet-942	586	5	17	17	NUM
admet-942	586	6	(	(	PUNCT
admet-942	586	7	2017	2017	NUM
admet-942	586	8	)	)	PUNCT
admet-942	586	9	23952420	23952420	NUM
admet-942	586	10	.	.	PUNCT
admet-942	587	1	https://doi.org/10.1039/c6lc01554a	https://doi.org/10.1039/c6lc01554a	NOUN
admet-942	587	2	.	.	PUNCT
admet-942	588	1	[	[	X
admet-942	588	2	18	18	NUM
admet-942	588	3	]	]	X
admet-942	588	4	c.	c.	PROPN
admet-942	588	5	probst	probst	PROPN
admet-942	588	6	,	,	PUNCT
admet-942	588	7	s.	s.	PROPN
admet-942	588	8	schneider	schneider	PROPN
admet-942	588	9	,	,	PUNCT
admet-942	588	10	p.	p.	PROPN
admet-942	588	11	loskill	loskill	PROPN
admet-942	588	12	.	.	PUNCT
admet-942	589	1	high	high	ADJ
admet-942	589	2	-	-	PUNCT
admet-942	589	3	throughput	throughput	NOUN
admet-942	589	4	organ	organ	NOUN
admet-942	589	5	-	-	PUNCT
admet-942	589	6	on	on	ADP
admet-942	589	7	-	-	PUNCT
admet-942	589	8	a	a	DET
admet-942	589	9	-	-	PUNCT
admet-942	589	10	chip	chip	NOUN
admet-942	589	11	systems	system	NOUN
admet-942	589	12	:	:	PUNCT
admet-942	589	13	current	current	ADJ
admet-942	589	14	status	status	NOUN
admet-942	589	15	and	and	CCONJ
admet-942	589	16	remaining	remain	VERB
admet-942	589	17	challenges	challenge	NOUN
admet-942	589	18	.	.	PUNCT
admet-942	590	1	current	current	ADJ
admet-942	590	2	opinion	opinion	NOUN
admet-942	590	3	in	in	ADP
admet-942	590	4	biomedical	biomedical	ADJ
admet-942	590	5	engineering	engineering	NOUN
admet-942	590	6	6	6	NUM
admet-942	590	7	(	(	PUNCT
admet-942	590	8	2018	2018	NUM
admet-942	590	9	)	)	PUNCT
admet-942	590	10	33	33	NUM
admet-942	590	11	-	-	SYM
admet-942	590	12	41	41	NUM
admet-942	590	13	.	.	PUNCT
admet-942	591	1	https://doi.org/10.1016/j.cobme.2018.02.004	https://doi.org/10.1016/j.cobme.2018.02.004	NOUN
admet-942	591	2	.	.	PUNCT
admet-942	592	1	[	[	X
admet-942	592	2	19	19	NUM
admet-942	592	3	]	]	X
admet-942	592	4	u.	u.	PROPN
admet-942	592	5	marx	marx	PROPN
admet-942	592	6	,	,	PUNCT
admet-942	592	7	t.	t.	PROPN
admet-942	592	8	akabane	akabane	PROPN
admet-942	592	9	,	,	PUNCT
admet-942	592	10	t.b	t.b	PROPN
admet-942	592	11	.	.	PROPN
admet-942	592	12	andersson	andersson	PROPN
admet-942	592	13	,	,	PUNCT
admet-942	592	14	b.	b.	PROPN
admet-942	592	15	elizabeth	elizabeth	PROPN
admet-942	592	16	,	,	PUNCT
admet-942	592	17	m.	m.	NOUN
admet-942	592	18	beilmann	beilmann	PROPN
admet-942	592	19	,	,	PUNCT
admet-942	592	20	s.	s.	PROPN
admet-942	592	21	beken	beken	VERB
admet-942	592	22	,	,	PUNCT
admet-942	592	23	s.	s.	PROPN
admet-942	592	24	brendler	brendler	NOUN
admet-942	592	25	-	-	PUNCT
admet-942	592	26	schwaab	schwaab	PROPN
admet-942	592	27	,	,	PUNCT
admet-942	592	28	m.	m.	NOUN
admet-942	592	29	cirit	cirit	PROPN
admet-942	592	30	,	,	PUNCT
admet-942	592	31	r.	r.	PROPN
admet-942	592	32	david	david	PROPN
admet-942	592	33	,	,	PUNCT
admet-942	592	34	e.-m	e.-m	PROPN
admet-942	592	35	.	.	PUNCT
admet-942	593	1	dehne	dehne	PROPN
admet-942	593	2	,	,	PUNCT
admet-942	593	3	i.	i.	PROPN
admet-942	593	4	durieux	durieux	PROPN
admet-942	593	5	,	,	PUNCT
admet-942	593	6	l.	l.	PROPN
admet-942	593	7	ewart	ewart	PROPN
admet-942	593	8	,	,	PUNCT
admet-942	593	9	s.c	s.c	PROPN
admet-942	593	10	.	.	PROPN
admet-942	593	11	fitzpatrick	fitzpatrick	PROPN
admet-942	593	12	,	,	PUNCT
admet-942	593	13	o.	o.	PROPN
admet-942	593	14	frey	frey	PROPN
admet-942	593	15	,	,	PUNCT
admet-942	593	16	f.	f.	PROPN
admet-942	593	17	fuchs	fuchs	PROPN
admet-942	593	18	,	,	PUNCT
admet-942	593	19	l.g	l.g	PROPN
admet-942	593	20	.	.	PROPN
admet-942	593	21	griffith	griffith	PROPN
admet-942	593	22	,	,	PUNCT
admet-942	593	23	g.a	g.a	PROPN
admet-942	593	24	.	.	PROPN
admet-942	593	25	hamilton	hamilton	PROPN
admet-942	593	26	,	,	PUNCT
admet-942	593	27	t.	t.	PROPN
admet-942	593	28	hartung	hartung	PROPN
admet-942	593	29	,	,	PUNCT
admet-942	593	30	j.	j.	PROPN
admet-942	593	31	hoeng	hoeng	PROPN
admet-942	593	32	,	,	PUNCT
admet-942	593	33	h.	h.	PROPN
admet-942	593	34	hogberg	hogberg	PROPN
admet-942	593	35	,	,	PUNCT
admet-942	593	36	d.j	d.j	PROPN
admet-942	593	37	.	.	PROPN
admet-942	593	38	hughes	hughes	PROPN
admet-942	593	39	,	,	PUNCT
admet-942	593	40	d.e	d.e	PROPN
admet-942	593	41	.	.	PROPN
admet-942	593	42	ingber	ingber	PROPN
admet-942	593	43	,	,	PUNCT
admet-942	593	44	a.	a.	PROPN
admet-942	593	45	iskandar	iskandar	PROPN
admet-942	593	46	,	,	PUNCT
admet-942	593	47	t.	t.	PROPN
admet-942	593	48	kanamori	kanamori	PROPN
admet-942	593	49	,	,	PUNCT
admet-942	593	50	h.	h.	PROPN
admet-942	593	51	kojima	kojima	PROPN
admet-942	593	52	,	,	PUNCT
admet-942	593	53	j.	j.	PROPN
admet-942	593	54	kuehnl	kuehnl	PROPN
admet-942	593	55	,	,	PUNCT
admet-942	593	56	m.	m.	NOUN
admet-942	593	57	leist	leist	NOUN
admet-942	593	58	,	,	PUNCT
admet-942	593	59	b.	b.	PROPN
admet-942	593	60	li	li	PROPN
admet-942	593	61	,	,	PUNCT
admet-942	593	62	p.	p.	PROPN
admet-942	593	63	loskill	loskill	PROPN
admet-942	593	64	,	,	PUNCT
admet-942	593	65	d.l	d.l	PROPN
admet-942	593	66	.	.	PROPN
admet-942	593	67	mendrick	mendrick	PROPN
admet-942	593	68	,	,	PUNCT
admet-942	593	69	thomas	thomas	PROPN
admet-942	593	70	neu	neu	PROPN
admet-942	593	71	,	,	PUNCT
admet-942	593	72	g.	g.	PROPN
admet-942	593	73	pallocca	pallocca	PROPN
admet-942	593	74	,	,	PUNCT
admet-942	593	75	i.	i.	PROPN
admet-942	593	76	rusyn	rusyn	PROPN
admet-942	593	77	,	,	PUNCT
admet-942	593	78	l.	l.	PROPN
admet-942	593	79	smirnova	smirnova	PROPN
admet-942	593	80	,	,	PUNCT
admet-942	593	81	t.	t.	PROPN
admet-942	593	82	steger	steger	PROPN
admet-942	593	83	-	-	PUNCT
admet-942	593	84	hartmann	hartmann	PROPN
admet-942	593	85	,	,	PUNCT
admet-942	593	86	d.a	d.a	PROPN
admet-942	593	87	.	.	PROPN
admet-942	593	88	tagle	tagle	PROPN
admet-942	593	89	,	,	PUNCT
admet-942	593	90	a.	a.	NOUN
admet-942	593	91	tonevitsky	tonevitsky	NOUN
admet-942	593	92	,	,	PUNCT
admet-942	593	93	s.	s.	PROPN
admet-942	593	94	tsyb	tsyb	PROPN
admet-942	593	95	,	,	PUNCT
admet-942	593	96	m.	m.	NOUN
admet-942	593	97	trapecar	trapecar	NOUN
admet-942	593	98	,	,	PUNCT
admet-942	593	99	b.	b.	PROPN
admet-942	593	100	van	van	PROPN
admet-942	593	101	de	de	PROPN
admet-942	593	102	water	water	PROPN
admet-942	593	103	,	,	PUNCT
admet-942	593	104	van	van	PROPN
admet-942	593	105	den	den	PROPN
admet-942	593	106	e.r	e.r	PROPN
admet-942	593	107	.	.	PROPN
admet-942	593	108	janny	janny	PROPN
admet-942	593	109	,	,	PUNCT
admet-942	593	110	p.	p.	NOUN
admet-942	593	111	vulto	vulto	PROPN
admet-942	593	112	,	,	PUNCT
admet-942	593	113	k.	k.	PROPN
admet-942	593	114	watanabe	watanabe	PROPN
admet-942	593	115	,	,	PUNCT
admet-942	593	116	a.	a.	NOUN
admet-942	593	117	wolf	wolf	PROPN
admet-942	593	118	,	,	PUNCT
admet-942	593	119	x.	x.	NOUN
admet-942	593	120	zhou	zhou	PROPN
admet-942	593	121	,	,	PUNCT
admet-942	593	122	a.	a.	PROPN
admet-942	593	123	roth	roth	PROPN
admet-942	593	124	.	.	PUNCT
admet-942	594	1	biology	biology	NOUN
admet-942	594	2	-	-	PUNCT
admet-942	594	3	inspired	inspire	VERB
admet-942	594	4	microphysiological	microphysiological	ADJ
admet-942	594	5	systems	system	NOUN
admet-942	594	6	to	to	PART
admet-942	594	7	advance	advance	VERB
admet-942	594	8	patient	patient	ADJ
admet-942	594	9	benefit	benefit	NOUN
admet-942	594	10	and	and	CCONJ
admet-942	594	11	animal	animal	NOUN
admet-942	594	12	welfare	welfare	NOUN
admet-942	594	13	in	in	ADP
admet-942	594	14	drug	drug	NOUN
admet-942	594	15	development	development	NOUN
admet-942	594	16	.	.	PUNCT
admet-942	595	1	t4	t4	PROPN
admet-942	595	2	the	the	DET
admet-942	595	3	transatlantic	transatlantic	ADJ
admet-942	595	4	think	think	NOUN
admet-942	595	5	tank	tank	NOUN
admet-942	595	6	for	for	ADP
admet-942	595	7	toxicology	toxicology	NOUN
admet-942	595	8	workshop	workshop	NOUN
admet-942	595	9	report	report	NOUN
admet-942	595	10	37	37	NUM
admet-942	595	11	(	(	PUNCT
admet-942	595	12	2020	2020	NUM
admet-942	595	13	)	)	PUNCT
admet-942	595	14	1	1	NUM
admet-942	595	15	-	-	SYM
admet-942	595	16	30	30	NUM
admet-942	595	17	.	.	PUNCT
admet-942	596	1	https://doi.org/10.14573/altex.2001241	https://doi.org/10.14573/altex.2001241	NOUN
admet-942	596	2	.	.	PUNCT
admet-942	597	1	[	[	X
admet-942	597	2	20	20	NUM
admet-942	597	3	]	]	PUNCT
admet-942	597	4	z.	z.	PROPN
admet-942	597	5	wang	wang	PROPN
admet-942	597	6	,	,	PUNCT
admet-942	597	7	x.	x.	PROPN
admet-942	598	1	he	he	PRON
admet-942	598	2	,	,	PUNCT
admet-942	598	3	h.	h.	PROPN
admet-942	598	4	qiao	qiao	PROPN
admet-942	598	5	,	,	PUNCT
admet-942	598	6	p.	p.	NOUN
admet-942	598	7	chen	chen	PROPN
admet-942	598	8	.	.	PUNCT
admet-942	599	1	global	global	ADJ
admet-942	599	2	trends	trend	NOUN
admet-942	599	3	of	of	ADP
admet-942	599	4	organoid	organoid	NOUN
admet-942	599	5	and	and	CCONJ
admet-942	599	6	organ	organ	NOUN
admet-942	599	7	-	-	PUNCT
admet-942	599	8	on	on	ADP
admet-942	599	9	-	-	PUNCT
admet-942	599	10	a	a	DET
admet-942	599	11	-	-	PUNCT
admet-942	599	12	chip	chip	NOUN
admet-942	599	13	in	in	ADP
admet-942	599	14	the	the	DET
admet-942	599	15	past	past	ADJ
admet-942	599	16	decade	decade	NOUN
admet-942	599	17	:	:	PUNCT
admet-942	599	18	a	a	DET
admet-942	599	19	bibliometric	bibliometric	ADJ
admet-942	599	20	and	and	CCONJ
admet-942	599	21	comparative	comparative	ADJ
admet-942	599	22	study	study	NOUN
admet-942	599	23	.	.	PUNCT
admet-942	600	1	tissue	tissue	NOUN
admet-942	600	2	engineering	engineering	NOUN
admet-942	600	3	part	part	NOUN
admet-942	600	4	a	a	DET
admet-942	600	5	00	00	NUM
admet-942	600	6	(	(	PUNCT
admet-942	600	7	2020	2020	NUM
admet-942	600	8	)	)	PUNCT
admet-942	600	9	1	1	NUM
admet-942	600	10	-	-	SYM
admet-942	600	11	16	16	NUM
admet-942	600	12	.	.	PUNCT
admet-942	601	1	https://doi.org/10.1089/ten.tea.2019.0251	https://doi.org/10.1089/ten.tea.2019.0251	PROPN
admet-942	601	2	.	.	PUNCT
admet-942	602	1	[	[	X
admet-942	602	2	21	21	NUM
admet-942	602	3	]	]	PUNCT
admet-942	602	4	m.	m.	NOUN
admet-942	602	5	rothbauer	rothbauer	NOUN
admet-942	602	6	,	,	PUNCT
admet-942	602	7	j.m	j.m	PROPN
admet-942	602	8	.	.	PROPN
admet-942	602	9	rosser	rosser	PROPN
admet-942	602	10	,	,	PUNCT
admet-942	602	11	h.	h.	PROPN
admet-942	602	12	zirath	zirath	PROPN
admet-942	602	13	,	,	PUNCT
admet-942	602	14	p.	p.	PROPN
admet-942	602	15	ertl	ertl	PROPN
admet-942	602	16	.	.	PUNCT
admet-942	603	1	tomorrow	tomorrow	NOUN
admet-942	603	2	today	today	NOUN
admet-942	603	3	:	:	PUNCT
admet-942	603	4	organ	organ	NOUN
admet-942	603	5	-	-	PUNCT
admet-942	603	6	on	on	ADP
admet-942	603	7	-	-	PUNCT
admet-942	603	8	a	a	DET
admet-942	603	9	-	-	PUNCT
admet-942	603	10	chip	chip	NOUN
admet-942	603	11	advances	advance	NOUN
admet-942	603	12	towards	towards	ADP
admet-942	603	13	clinically	clinically	ADV
admet-942	603	14	relevant	relevant	ADJ
admet-942	603	15	pharmaceutical	pharmaceutical	NOUN
admet-942	603	16	and	and	CCONJ
admet-942	603	17	medical	medical	ADJ
admet-942	603	18	in	in	ADP
admet-942	603	19	vitro	vitro	X
admet-942	603	20	models	model	NOUN
admet-942	603	21	.	.	PUNCT
admet-942	604	1	current	current	ADJ
admet-942	604	2	opinion	opinion	NOUN
admet-942	604	3	in	in	ADP
admet-942	604	4	biotechnology	biotechnology	NOUN
admet-942	604	5	55	55	NUM
admet-942	604	6	(	(	PUNCT
admet-942	604	7	2019	2019	NUM
admet-942	604	8	)	)	PUNCT
admet-942	604	9	81	81	NUM
admet-942	604	10	-	-	SYM
admet-942	604	11	86	86	NUM
admet-942	604	12	.	.	PUNCT
admet-942	605	1	https://doi.org/10.1016/j.copbio.2018.08.009	https://doi.org/10.1016/j.copbio.2018.08.009	NUM
admet-942	605	2	.	.	PUNCT
admet-942	606	1	[	[	X
admet-942	606	2	22	22	NUM
admet-942	606	3	]	]	PUNCT
admet-942	606	4	z.	z.	PROPN
admet-942	606	5	wang	wang	PROPN
admet-942	606	6	,	,	PUNCT
admet-942	606	7	x.	x.	PROPN
admet-942	606	8	he	he	PRON
admet-942	606	9	,	,	PUNCT
admet-942	606	10	h.	h.	PROPN
admet-942	606	11	qiao	qiao	PROPN
admet-942	606	12	,	,	PUNCT
admet-942	606	13	p.	p.	NOUN
admet-942	606	14	chen	chen	PROPN
admet-942	606	15	.	.	PUNCT
admet-942	607	1	global	global	ADJ
admet-942	607	2	trends	trend	NOUN
admet-942	607	3	of	of	ADP
admet-942	607	4	organoid	organoid	NOUN
admet-942	607	5	and	and	CCONJ
admet-942	607	6	organ	organ	NOUN
admet-942	607	7	-	-	PUNCT
admet-942	607	8	on	on	ADP
admet-942	607	9	-	-	PUNCT
admet-942	607	10	a	a	DET
admet-942	607	11	-	-	PUNCT
admet-942	607	12	chip	chip	NOUN
admet-942	607	13	in	in	ADP
admet-942	607	14	the	the	DET
admet-942	607	15	past	past	ADJ
admet-942	607	16	decade	decade	NOUN
admet-942	607	17	:	:	PUNCT
admet-942	607	18	a	a	DET
admet-942	607	19	bibliometric	bibliometric	ADJ
admet-942	607	20	and	and	CCONJ
admet-942	607	21	comparative	comparative	ADJ
admet-942	607	22	study	study	NOUN
admet-942	607	23	.	.	PUNCT
admet-942	608	1	tissue	tissue	NOUN
admet-942	608	2	engineering	engineering	NOUN
admet-942	608	3	part	part	NOUN
admet-942	608	4	a	a	DET
admet-942	608	5	26	26	NUM
admet-942	608	6	(	(	PUNCT
admet-942	608	7	2020	2020	NUM
admet-942	608	8	)	)	PUNCT
admet-942	608	9	656	656	NUM
admet-942	608	10	-	-	SYM
admet-942	608	11	671	671	NUM
admet-942	608	12	.	.	PUNCT
admet-942	609	1	https://doi.org/10.1089/ten.tea.2019.0251	https://doi.org/10.1089/ten.tea.2019.0251	X
admet-942	609	2	.	.	PUNCT
admet-942	610	1	[	[	X
admet-942	610	2	23	23	NUM
admet-942	610	3	]	]	X
admet-942	610	4	c.	c.	PROPN
admet-942	610	5	arrigoni	arrigoni	PROPN
admet-942	610	6	,	,	PUNCT
admet-942	610	7	s.	s.	PROPN
admet-942	610	8	lopa	lopa	PROPN
admet-942	610	9	,	,	PUNCT
admet-942	610	10	c.	c.	PROPN
admet-942	610	11	candrian	candrian	PROPN
admet-942	610	12	,	,	PUNCT
admet-942	610	13	m.	m.	PROPN
admet-942	610	14	moretti	moretti	PROPN
admet-942	610	15	.	.	PUNCT
admet-942	611	1	organs	organ	NOUN
admet-942	611	2	-	-	PUNCT
admet-942	611	3	on	on	ADP
admet-942	611	4	-	-	PUNCT
admet-942	611	5	a	a	DET
admet-942	611	6	-	-	PUNCT
admet-942	611	7	chip	chip	NOUN
admet-942	611	8	as	as	ADP
admet-942	611	9	model	model	NOUN
admet-942	611	10	systems	system	NOUN
admet-942	611	11	for	for	ADP
admet-942	611	12	multifactorial	multifactorial	ADJ
admet-942	611	13	musculoskeletal	musculoskeletal	ADJ
admet-942	611	14	diseases	disease	NOUN
admet-942	611	15	.	.	PUNCT
admet-942	612	1	current	current	ADJ
admet-942	612	2	opinion	opinion	NOUN
admet-942	612	3	in	in	ADP
admet-942	612	4	biotechnology	biotechnology	NOUN
admet-942	612	5	63	63	NUM
admet-942	612	6	(	(	PUNCT
admet-942	612	7	2020	2020	NUM
admet-942	612	8	)	)	PUNCT
admet-942	612	9	79	79	NUM
admet-942	612	10	-	-	SYM
admet-942	612	11	88	88	NUM
admet-942	612	12	.	.	PUNCT
admet-942	613	1	https://doi.org/10.1016/j.copbio.2019.12.006	https://doi.org/10.1016/j.copbio.2019.12.006	ADJ
admet-942	613	2	.	.	PUNCT
admet-942	614	1	[	[	X
admet-942	614	2	24	24	NUM
admet-942	614	3	]	]	X
admet-942	614	4	s.r	s.r	PROPN
admet-942	614	5	.	.	PROPN
admet-942	614	6	adam	adam	PROPN
admet-942	614	7	kratz	kratz	PROPN
admet-942	614	8	,	,	PUNCT
admet-942	614	9	g.	g.	PROPN
admet-942	614	10	höll	höll	PROPN
admet-942	614	11	,	,	PUNCT
admet-942	614	12	p.	p.	NOUN
admet-942	614	13	schuller	schuller	NOUN
admet-942	614	14	,	,	PUNCT
admet-942	614	15	p.	p.	PROPN
admet-942	614	16	ertl	ertl	PROPN
admet-942	614	17	,	,	PUNCT
admet-942	614	18	m.	m.	NOUN
admet-942	614	19	rothbauer	rothbauer	NOUN
admet-942	614	20	.	.	PUNCT
admet-942	615	1	latest	late	ADJ
admet-942	615	2	trends	trend	NOUN
admet-942	615	3	in	in	ADP
admet-942	615	4	biosensing	biosense	VERB
admet-942	615	5	for	for	ADP
admet-942	615	6	microphysiological	microphysiological	ADJ
admet-942	615	7	organs	organ	NOUN
admet-942	615	8	-	-	PUNCT
admet-942	615	9	on	on	ADP
admet-942	615	10	-	-	PUNCT
admet-942	615	11	a	a	DET
admet-942	615	12	-	-	PUNCT
admet-942	615	13	chip	chip	NOUN
admet-942	615	14	and	and	CCONJ
admet-942	615	15	body	body	NOUN
admet-942	615	16	-	-	PUNCT
admet-942	615	17	on	on	ADP
admet-942	615	18	-	-	PUNCT
admet-942	615	19	a	a	DET
admet-942	615	20	-	-	PUNCT
admet-942	615	21	chip	chip	NOUN
admet-942	615	22	systems	system	NOUN
admet-942	615	23	.	.	PUNCT
admet-942	616	1	biosensors	biosensor	NOUN
admet-942	616	2	9	9	NUM
admet-942	616	3	(	(	PUNCT
admet-942	616	4	2019	2019	NUM
admet-942	616	5	)	)	PUNCT
admet-942	616	6	.	.	PUNCT
admet-942	617	1	https://doi.org/10.3390/bios9030110	https://doi.org/10.3390/bios9030110	PROPN
admet-942	617	2	.	.	PUNCT
admet-942	618	1	[	[	X
admet-942	618	2	25	25	NUM
admet-942	618	3	]	]	X
admet-942	618	4	m.m	m.m	PROPN
admet-942	618	5	.	.	PROPN
admet-942	618	6	silva	silva	PROPN
admet-942	618	7	.	.	PUNCT
admet-942	619	1	voyage	voyage	NOUN
admet-942	619	2	from	from	ADP
admet-942	619	3	fiction	fiction	NOUN
admet-942	619	4	to	to	ADP
admet-942	619	5	reality	reality	NOUN
admet-942	619	6	:	:	PUNCT
admet-942	619	7	organs	organ	NOUN
admet-942	619	8	-	-	PUNCT
admet-942	619	9	on	on	ADP
admet-942	619	10	-	-	PUNCT
admet-942	619	11	chips	chip	NOUN
admet-942	619	12	in	in	ADP
admet-942	619	13	the	the	DET
admet-942	619	14	service	service	NOUN
admet-942	619	15	of	of	ADP
admet-942	619	16	science	science	NOUN
admet-942	619	17	and	and	CCONJ
admet-942	619	18	medicine	medicine	NOUN
admet-942	619	19	.	.	PUNCT
admet-942	620	1	revista	revista	PROPN
admet-942	620	2	odontológica	odontológica	NOUN
admet-942	620	3	mexicana	mexicana	PROPN
admet-942	620	4	20	20	NUM
admet-942	620	5	(	(	PUNCT
admet-942	620	6	2016	2016	NUM
admet-942	620	7	)	)	PUNCT
admet-942	620	8	74	74	NUM
admet-942	620	9	-	-	SYM
admet-942	620	10	75	75	NUM
admet-942	620	11	.	.	PUNCT
admet-942	621	1	https://doi.org/10.1016/j.rodmex.2016.04.010	https://doi.org/10.1016/j.rodmex.2016.04.010	PROPN
admet-942	621	2	.	.	PUNCT
admet-942	622	1	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	622	2	https://doi.org/10.1016/j.biomaterials.2018.07.062	https://doi.org/10.1016/j.biomaterials.2018.07.062	PROPN
admet-942	622	3	https://doi.org/10.1016/j.biomaterials.2018.07.062	https://doi.org/10.1016/j.biomaterials.2018.07.062	PRON
admet-942	622	4	https://doi.org/10.1016/j.stem.2018.02.011	https://doi.org/10.1016/j.stem.2018.02.011	NUM
admet-942	622	5	https://doi.org/10.1016/j.stem.2018.02.011	https://doi.org/10.1016/j.stem.2018.02.011	PRON
admet-942	622	6	https://doi.org/10.3390/mi10100688	https://doi.org/10.3390/mi10100688	SYM
admet-942	622	7	https://doi.org/10.1016/j.cell.2020.04.004	https://doi.org/10.1016/j.cell.2020.04.004	X
admet-942	622	8	https://doi.org/10.1016/j.cell.2020.04.004	https://doi.org/10.1016/j.cell.2020.04.004	PROPN
admet-942	622	9	https://doi.org/10.1039/c6lc01554a	https://doi.org/10.1039/c6lc01554a	PROPN
admet-942	622	10	https://doi.org/10.14573/altex.2001241	https://doi.org/10.14573/altex.2001241	X
admet-942	622	11	https://doi.org/10.1016/j.copbio.2018.08.009	https://doi.org/10.1016/j.copbio.2018.08.009	PROPN
admet-942	622	12	https://doi.org/10.1089/ten.tea.2019.0251	https://doi.org/10.1089/ten.tea.2019.0251	PROPN
admet-942	622	13	https://doi.org/10.3390/bios9030110	https://doi.org/10.3390/bios9030110	PROPN
admet-942	622	14	https://doi.org/10.1016/j.rodmex.2016.04.010	https://doi.org/10.1016/j.rodmex.2016.04.010	PROPN
admet-942	622	15	r.	r.	PROPN
admet-942	622	16	vargas	vargas	PROPN
admet-942	622	17	,	,	PUNCT
admet-942	622	18	a.	a.	NOUN
admet-942	622	19	egurbide	egurbide	NOUN
admet-942	622	20	-	-	PUNCT
admet-942	622	21	sifre	sifre	NOUN
admet-942	622	22	and	and	CCONJ
admet-942	622	23	l.	l.	PROPN
admet-942	622	24	medina	medina	PROPN
admet-942	622	25	admet	admet	PROPN
admet-942	622	26	&	&	CCONJ
admet-942	622	27	dmpk	dmpk	PROPN
admet-942	622	28	9(2	9(2	NUM
admet-942	622	29	)	)	PUNCT
admet-942	622	30	(	(	PUNCT
admet-942	622	31	2021	2021	NUM
admet-942	622	32	)	)	PUNCT
admet-942	622	33	111	111	NUM
admet-942	622	34	-	-	SYM
admet-942	622	35	141	141	NUM
admet-942	622	36	134	134	NUM
admet-942	623	1	[	[	X
admet-942	623	2	26	26	NUM
admet-942	623	3	]	]	X
admet-942	623	4	f.	f.	PROPN
admet-942	623	5	zheng	zheng	PROPN
admet-942	623	6	,	,	PUNCT
admet-942	623	7	f.	f.	PROPN
admet-942	623	8	fu	fu	PROPN
admet-942	623	9	,	,	PUNCT
admet-942	623	10	y.	y.	PROPN
admet-942	623	11	cheng	cheng	PROPN
admet-942	623	12	,	,	PUNCT
admet-942	623	13	c.	c.	PROPN
admet-942	623	14	wang	wang	PROPN
admet-942	623	15	,	,	PUNCT
admet-942	623	16	y.	y.	PROPN
admet-942	623	17	zhao	zhao	PROPN
admet-942	623	18	,	,	PUNCT
admet-942	623	19	z.	z.	PROPN
admet-942	623	20	gu	gu	PROPN
admet-942	623	21	.	.	PROPN
admet-942	623	22	organ	organ	PROPN
admet-942	623	23	-	-	PUNCT
admet-942	623	24	on	on	ADP
admet-942	623	25	-	-	PUNCT
admet-942	623	26	a	a	DET
admet-942	623	27	-	-	PUNCT
admet-942	623	28	chip	chip	NOUN
admet-942	623	29	systems	system	NOUN
admet-942	623	30	:	:	PUNCT
admet-942	623	31	microengineering	microengineere	VERB
admet-942	623	32	to	to	ADP
admet-942	623	33	biomimic	biomimic	ADJ
admet-942	623	34	living	living	NOUN
admet-942	623	35	systems	system	NOUN
admet-942	623	36	.	.	PUNCT
admet-942	624	1	small	small	ADJ
admet-942	624	2	12	12	NUM
admet-942	624	3	(	(	PUNCT
admet-942	624	4	2016	2016	NUM
admet-942	624	5	)	)	PUNCT
admet-942	624	6	2253	2253	NUM
admet-942	624	7	-	-	SYM
admet-942	624	8	2282	2282	NUM
admet-942	624	9	.	.	PUNCT
admet-942	625	1	https://doi.org/10.1002/smll.201503208	https://doi.org/10.1002/smll.201503208	ADJ
admet-942	625	2	.	.	PUNCT
admet-942	626	1	[	[	X
admet-942	626	2	27	27	NUM
admet-942	626	3	]	]	X
admet-942	626	4	h.	h.	PROPN
admet-942	626	5	kimura	kimura	PROPN
admet-942	626	6	,	,	PUNCT
admet-942	626	7	y.	y.	PROPN
admet-942	626	8	sakai	sakai	PROPN
admet-942	626	9	,	,	PUNCT
admet-942	626	10	t.	t.	PROPN
admet-942	626	11	fujii	fujii	PROPN
admet-942	626	12	.	.	PUNCT
admet-942	627	1	organ	organ	NOUN
admet-942	627	2	/	/	SYM
admet-942	627	3	body	body	NOUN
admet-942	627	4	-	-	PUNCT
admet-942	627	5	on	on	ADP
admet-942	627	6	-	-	PUNCT
admet-942	627	7	a	a	DET
admet-942	627	8	-	-	PUNCT
admet-942	627	9	chip	chip	NOUN
admet-942	627	10	based	base	VERB
admet-942	627	11	on	on	ADP
admet-942	627	12	microfluidic	microfluidic	ADJ
admet-942	627	13	technology	technology	NOUN
admet-942	627	14	for	for	ADP
admet-942	627	15	drug	drug	NOUN
admet-942	627	16	discovery	discovery	NOUN
admet-942	627	17	.	.	PUNCT
admet-942	628	1	drug	drug	NOUN
admet-942	628	2	metabolism	metabolism	NOUN
admet-942	628	3	and	and	CCONJ
admet-942	628	4	pharmacokinetics	pharmacokinetic	NOUN
admet-942	628	5	33	33	NUM
admet-942	628	6	(	(	PUNCT
admet-942	628	7	2018	2018	NUM
admet-942	628	8	)	)	PUNCT
admet-942	628	9	43	43	NUM
admet-942	628	10	-	-	SYM
admet-942	628	11	48	48	NUM
admet-942	628	12	.	.	PUNCT
admet-942	629	1	https://doi.org/10.1016/j.dmpk.2017.11.003	https://doi.org/10.1016/j.dmpk.2017.11.003	NUM
admet-942	629	2	.	.	PUNCT
admet-942	630	1	[	[	X
admet-942	630	2	28	28	NUM
admet-942	630	3	]	]	X
admet-942	630	4	j.y	j.y	PROPN
admet-942	630	5	.	.	PROPN
admet-942	630	6	park	park	PROPN
admet-942	630	7	,	,	PUNCT
admet-942	630	8	j.	j.	PROPN
admet-942	630	9	jang	jang	PROPN
admet-942	630	10	,	,	PUNCT
admet-942	630	11	h.w	h.w	PROPN
admet-942	630	12	.	.	PROPN
admet-942	630	13	kang	kang	PROPN
admet-942	630	14	.	.	PUNCT
admet-942	631	1	3d	3d	PROPN
admet-942	631	2	bioprinting	bioprinting	NOUN
admet-942	631	3	and	and	CCONJ
admet-942	631	4	its	its	PRON
admet-942	631	5	application	application	NOUN
admet-942	631	6	to	to	ADP
admet-942	631	7	organ	organ	VERB
admet-942	631	8	-	-	PUNCT
admet-942	631	9	on	on	ADP
admet-942	631	10	-	-	PUNCT
admet-942	631	11	a	a	DET
admet-942	631	12	-	-	PUNCT
admet-942	631	13	chip	chip	NOUN
admet-942	631	14	.	.	PUNCT
admet-942	632	1	microelectronic	microelectronic	ADJ
admet-942	632	2	engineering	engineering	NOUN
admet-942	632	3	200	200	NUM
admet-942	632	4	(	(	PUNCT
admet-942	632	5	2018	2018	NUM
admet-942	632	6	)	)	PUNCT
admet-942	632	7	1	1	NUM
admet-942	632	8	-	-	SYM
admet-942	632	9	11	11	NUM
admet-942	632	10	.	.	PUNCT
admet-942	633	1	https://doi.org/10.1016/j.mee.2018.08.004	https://doi.org/10.1016/j.mee.2018.08.004	PROPN
admet-942	633	2	.	.	PUNCT
admet-942	634	1	[	[	X
admet-942	634	2	29	29	NUM
admet-942	634	3	]	]	PUNCT
admet-942	634	4	a.	a.	NOUN
admet-942	634	5	junaid	junaid	PROPN
admet-942	634	6	,	,	PUNCT
admet-942	634	7	a.	a.	PROPN
admet-942	634	8	mashaghi	mashaghi	PROPN
admet-942	634	9	,	,	PUNCT
admet-942	634	10	t.	t.	NOUN
admet-942	634	11	hankemeier	hankemeier	NOUN
admet-942	634	12	,	,	PUNCT
admet-942	634	13	p.	p.	NOUN
admet-942	634	14	vulto	vulto	NOUN
admet-942	634	15	.	.	PUNCT
admet-942	635	1	an	an	DET
admet-942	635	2	end	end	NOUN
admet-942	635	3	-	-	PUNCT
admet-942	635	4	user	user	NOUN
admet-942	635	5	perspective	perspective	NOUN
admet-942	635	6	on	on	ADP
admet-942	635	7	organ	organ	NOUN
admet-942	635	8	-	-	PUNCT
admet-942	635	9	on	on	ADP
admet-942	635	10	-	-	PUNCT
admet-942	635	11	a	a	DET
admet-942	635	12	-	-	PUNCT
admet-942	635	13	chip	chip	NOUN
admet-942	635	14	:	:	PUNCT
admet-942	635	15	assays	assay	NOUN
admet-942	635	16	and	and	CCONJ
admet-942	635	17	usability	usability	NOUN
admet-942	635	18	aspects	aspect	NOUN
admet-942	635	19	.	.	PUNCT
admet-942	636	1	current	current	ADJ
admet-942	636	2	opinion	opinion	NOUN
admet-942	636	3	in	in	ADP
admet-942	636	4	biomedical	biomedical	ADJ
admet-942	636	5	engineering	engineering	NOUN
admet-942	636	6	1	1	NUM
admet-942	636	7	(	(	PUNCT
admet-942	636	8	2017	2017	NUM
admet-942	636	9	)	)	PUNCT
admet-942	636	10	15	15	NUM
admet-942	636	11	-	-	SYM
admet-942	636	12	22	22	NUM
admet-942	636	13	.	.	PUNCT
admet-942	637	1	https://doi.org/10.1016/j.cobme.2017.02.002	https://doi.org/10.1016/j.cobme.2017.02.002	NOUN
admet-942	637	2	.	.	PUNCT
admet-942	638	1	[	[	X
admet-942	638	2	30	30	NUM
admet-942	638	3	]	]	X
admet-942	638	4	c.	c.	PROPN
admet-942	638	5	tian	tian	PROPN
admet-942	638	6	,	,	PUNCT
admet-942	638	7	q.	q.	PROPN
admet-942	638	8	tu	tu	PROPN
admet-942	638	9	,	,	PUNCT
admet-942	638	10	w.	w.	PROPN
admet-942	638	11	liu	liu	PROPN
admet-942	638	12	,	,	PUNCT
admet-942	638	13	j.	j.	PROPN
admet-942	638	14	wang	wang	PROPN
admet-942	638	15	.	.	PUNCT
admet-942	639	1	recent	recent	ADJ
admet-942	639	2	advances	advance	NOUN
admet-942	639	3	in	in	ADP
admet-942	639	4	microfluidic	microfluidic	ADJ
admet-942	639	5	technologies	technology	NOUN
admet-942	639	6	for	for	ADP
admet-942	639	7	organ	organ	NOUN
admet-942	639	8	-	-	PUNCT
admet-942	639	9	on	on	ADP
admet-942	639	10	-	-	PUNCT
admet-942	639	11	a	a	DET
admet-942	639	12	-	-	PUNCT
admet-942	639	13	chip	chip	NOUN
admet-942	639	14	.	.	PUNCT
admet-942	640	1	trac	trac	NOUN
admet-942	640	2	trends	trend	NOUN
admet-942	640	3	in	in	ADP
admet-942	640	4	analytical	analytical	ADJ
admet-942	640	5	chemistry	chemistry	NOUN
admet-942	640	6	117	117	NUM
admet-942	640	7	(	(	PUNCT
admet-942	640	8	2019	2019	NUM
admet-942	640	9	)	)	PUNCT
admet-942	640	10	146	146	NUM
admet-942	640	11	-	-	SYM
admet-942	640	12	156	156	NUM
admet-942	640	13	.	.	PUNCT
admet-942	641	1	https://doi.org/10.1016/j.trac.2019.06.005	https://doi.org/10.1016/j.trac.2019.06.005	X
admet-942	641	2	.	.	PUNCT
admet-942	642	1	[	[	X
admet-942	642	2	31	31	NUM
admet-942	642	3	]	]	X
admet-942	642	4	d.e	d.e	PROPN
admet-942	642	5	.	.	PROPN
admet-942	642	6	ingber	ingber	PROPN
admet-942	642	7	.	.	PUNCT
admet-942	643	1	developmentally	developmentally	ADV
admet-942	643	2	inspired	inspire	VERB
admet-942	643	3	human	human	ADJ
admet-942	643	4	‘	'	PUNCT
admet-942	643	5	organs	organ	NOUN
admet-942	643	6	on	on	ADP
admet-942	643	7	chips	chip	NOUN
admet-942	643	8	’	'	PUNCT
admet-942	643	9	.	.	PUNCT
admet-942	644	1	development	development	NOUN
admet-942	644	2	(	(	PUNCT
admet-942	644	3	cambridge	cambridge	PROPN
admet-942	644	4	)	)	PUNCT
admet-942	644	5	145	145	NUM
admet-942	644	6	(	(	PUNCT
admet-942	644	7	2018	2018	NUM
admet-942	644	8	)	)	PUNCT
admet-942	644	9	10	10	NUM
admet-942	644	10	-	-	SYM
admet-942	644	11	13	13	NUM
admet-942	644	12	.	.	PUNCT
admet-942	645	1	https://doi.org/10.1242/dev.156125	https://doi.org/10.1242/dev.156125	PROPN
admet-942	645	2	.	.	PUNCT
admet-942	646	1	[	[	X
admet-942	646	2	32	32	NUM
admet-942	646	3	]	]	PUNCT
admet-942	646	4	p.	p.	PROPN
admet-942	646	5	ng	ng	PROPN
admet-942	646	6	,	,	PUNCT
admet-942	646	7	c.	c.	PROPN
admet-942	646	8	belgur	belgur	PROPN
admet-942	646	9	,	,	PUNCT
admet-942	646	10	s.	s.	PROPN
admet-942	646	11	barthakur	barthakur	PROPN
admet-942	646	12	,	,	PUNCT
admet-942	646	13	a.d	a.d	PROPN
admet-942	646	14	.	.	PROPN
admet-942	646	15	van	van	PROPN
admet-942	646	16	der	der	PROPN
admet-942	646	17	meer	meer	PROPN
admet-942	646	18	,	,	PUNCT
admet-942	646	19	g.a	g.a	PROPN
admet-942	646	20	.	.	PROPN
admet-942	646	21	hamilton	hamilton	PROPN
admet-942	646	22	,	,	PUNCT
admet-942	646	23	r.	r.	PROPN
admet-942	646	24	barrile	barrile	PROPN
admet-942	646	25	.	.	PUNCT
admet-942	647	1	organs	organ	NOUN
admet-942	647	2	-	-	PUNCT
admet-942	647	3	on	on	ADP
admet-942	647	4	-	-	PUNCT
admet-942	647	5	chips	chip	NOUN
admet-942	647	6	:	:	PUNCT
admet-942	647	7	a	a	DET
admet-942	647	8	new	new	ADJ
admet-942	647	9	paradigm	paradigm	NOUN
admet-942	647	10	for	for	ADP
admet-942	647	11	safety	safety	NOUN
admet-942	647	12	assessment	assessment	NOUN
admet-942	647	13	of	of	ADP
admet-942	647	14	drug	drug	NOUN
admet-942	647	15	-	-	PUNCT
admet-942	647	16	induced	induce	VERB
admet-942	647	17	thrombosis	thrombosis	NOUN
admet-942	647	18	.	.	PUNCT
admet-942	648	1	current	current	ADJ
admet-942	648	2	opinion	opinion	NOUN
admet-942	648	3	in	in	ADP
admet-942	648	4	toxicology	toxicology	NOUN
admet-942	648	5	17	17	NUM
admet-942	648	6	(	(	PUNCT
admet-942	648	7	2019	2019	NUM
admet-942	648	8	)	)	PUNCT
admet-942	648	9	1	1	NUM
admet-942	648	10	-	-	SYM
admet-942	648	11	8	8	NUM
admet-942	648	12	.	.	PUNCT
admet-942	649	1	https://doi.org/10.1016/j.cotox.2019.08.004	https://doi.org/10.1016/j.cotox.2019.08.004	PROPN
admet-942	649	2	.	.	PUNCT
admet-942	650	1	[	[	X
admet-942	650	2	33	33	NUM
admet-942	650	3	]	]	X
admet-942	650	4	c.	c.	PROPN
admet-942	650	5	tian	tian	PROPN
admet-942	650	6	,	,	PUNCT
admet-942	650	7	q.	q.	PROPN
admet-942	650	8	tu	tu	PROPN
admet-942	650	9	,	,	PUNCT
admet-942	650	10	w.	w.	PROPN
admet-942	650	11	liu	liu	PROPN
admet-942	650	12	,	,	PUNCT
admet-942	650	13	j.	j.	PROPN
admet-942	650	14	wang	wang	PROPN
admet-942	650	15	.	.	PUNCT
admet-942	651	1	recent	recent	ADJ
admet-942	651	2	advances	advance	NOUN
admet-942	651	3	in	in	ADP
admet-942	651	4	microfluidic	microfluidic	ADJ
admet-942	651	5	technologies	technology	NOUN
admet-942	651	6	for	for	ADP
admet-942	651	7	organ	organ	NOUN
admet-942	651	8	-	-	PUNCT
admet-942	651	9	on	on	ADP
admet-942	651	10	-	-	PUNCT
admet-942	651	11	a	a	DET
admet-942	651	12	-	-	PUNCT
admet-942	651	13	chip	chip	NOUN
admet-942	651	14	.	.	PUNCT
admet-942	652	1	trac	trac	NOUN
admet-942	652	2	trends	trend	NOUN
admet-942	652	3	in	in	ADP
admet-942	652	4	analytical	analytical	ADJ
admet-942	652	5	chemistry	chemistry	NOUN
admet-942	652	6	117	117	NUM
admet-942	652	7	(	(	PUNCT
admet-942	652	8	2019	2019	NUM
admet-942	652	9	)	)	PUNCT
admet-942	652	10	146	146	NUM
admet-942	652	11	-	-	SYM
admet-942	652	12	156	156	NUM
admet-942	652	13	.	.	PUNCT
admet-942	653	1	https://doi.org/10.1016/j.trac.2019.06.005	https://doi.org/10.1016/j.trac.2019.06.005	X
admet-942	653	2	.	.	PUNCT
admet-942	654	1	[	[	X
admet-942	654	2	34	34	NUM
admet-942	654	3	]	]	X
admet-942	654	4	f.	f.	PROPN
admet-942	654	5	yu	yu	PROPN
admet-942	654	6	,	,	PUNCT
admet-942	654	7	d.	d.	PROPN
admet-942	654	8	choudhury	choudhury	PROPN
admet-942	654	9	.	.	PUNCT
admet-942	654	10	microfluidic	microfluidic	ADJ
admet-942	654	11	bioprinting	bioprinting	NOUN
admet-942	654	12	for	for	ADP
admet-942	654	13	organ	organ	NOUN
admet-942	654	14	-	-	PUNCT
admet-942	654	15	on	on	ADP
admet-942	654	16	-	-	PUNCT
admet-942	654	17	a	a	DET
admet-942	654	18	-	-	PUNCT
admet-942	654	19	chip	chip	NOUN
admet-942	654	20	models	model	NOUN
admet-942	654	21	.	.	PUNCT
admet-942	655	1	drug	drug	NOUN
admet-942	655	2	discovery	discovery	PROPN
admet-942	655	3	today	today	NOUN
admet-942	655	4	24	24	NUM
admet-942	655	5	(	(	PUNCT
admet-942	655	6	2019	2019	NUM
admet-942	655	7	)	)	PUNCT
admet-942	655	8	1248	1248	NUM
admet-942	655	9	-	-	SYM
admet-942	655	10	1257	1257	NUM
admet-942	655	11	.	.	PUNCT
admet-942	656	1	https://doi.org/10.1016/j.drudis.2019.03.025	https://doi.org/10.1016/j.drudis.2019.03.025	NUM
admet-942	656	2	.	.	PUNCT
admet-942	657	1	[	[	X
admet-942	657	2	35	35	NUM
admet-942	657	3	]	]	X
admet-942	657	4	h.	h.	PROPN
admet-942	657	5	sun	sun	PROPN
admet-942	657	6	,	,	PUNCT
admet-942	657	7	y.	y.	PROPN
admet-942	657	8	jia	jia	PROPN
admet-942	657	9	,	,	PUNCT
admet-942	657	10	h.	h.	PROPN
admet-942	657	11	dong	dong	PROPN
admet-942	657	12	,	,	PUNCT
admet-942	657	13	d.	d.	PROPN
admet-942	657	14	dong	dong	PROPN
admet-942	657	15	,	,	PUNCT
admet-942	657	16	j.	j.	PROPN
admet-942	657	17	zheng	zheng	PROPN
admet-942	657	18	.	.	PUNCT
admet-942	658	1	combining	combine	VERB
admet-942	658	2	additive	additive	ADJ
admet-942	658	3	manufacturing	manufacturing	NOUN
admet-942	658	4	with	with	ADP
admet-942	658	5	microfluidics	microfluidic	NOUN
admet-942	658	6	:	:	PUNCT
admet-942	658	7	an	an	DET
admet-942	658	8	emerging	emerge	VERB
admet-942	658	9	method	method	NOUN
admet-942	658	10	for	for	ADP
admet-942	658	11	developing	develop	VERB
admet-942	658	12	novel	novel	ADJ
admet-942	658	13	organs	organ	NOUN
admet-942	658	14	-	-	PUNCT
admet-942	658	15	on	on	ADP
admet-942	658	16	-	-	PUNCT
admet-942	658	17	chips	chip	NOUN
admet-942	658	18	.	.	PUNCT
admet-942	659	1	current	current	ADJ
admet-942	659	2	opinion	opinion	NOUN
admet-942	659	3	in	in	ADP
admet-942	659	4	chemical	chemical	ADJ
admet-942	659	5	engineering	engineering	NOUN
admet-942	659	6	28	28	NUM
admet-942	659	7	(	(	PUNCT
admet-942	659	8	2020	2020	NUM
admet-942	659	9	)	)	PUNCT
admet-942	659	10	1	1	NUM
admet-942	659	11	-	-	SYM
admet-942	659	12	9	9	NUM
admet-942	659	13	.	.	PUNCT
admet-942	659	14	https://doi.org/10.1016/j.coche.2019.10.006	https://doi.org/10.1016/j.coche.2019.10.006	NOUN
admet-942	659	15	.	.	PUNCT
admet-942	660	1	[	[	X
admet-942	660	2	36	36	NUM
admet-942	660	3	]	]	PUNCT
admet-942	660	4	x.	x.	PROPN
admet-942	660	5	yu	yu	PROPN
admet-942	660	6	,	,	PUNCT
admet-942	660	7	n.	n.	PROPN
admet-942	660	8	wu	wu	PROPN
admet-942	660	9	,	,	PUNCT
admet-942	660	10	f.	f.	PROPN
admet-942	660	11	chen	chen	PROPN
admet-942	660	12	,	,	PUNCT
admet-942	660	13	j.	j.	PROPN
admet-942	660	14	wei	wei	PROPN
admet-942	660	15	,	,	PUNCT
admet-942	660	16	y.	y.	PROPN
admet-942	660	17	zhao	zhao	PROPN
admet-942	660	18	.	.	PUNCT
admet-942	661	1	engineering	engineer	VERB
admet-942	661	2	microfluidic	microfluidic	ADJ
admet-942	661	3	chip	chip	NOUN
admet-942	661	4	for	for	ADP
admet-942	661	5	circulating	circulate	VERB
admet-942	661	6	tumor	tumor	NOUN
admet-942	661	7	cells	cell	NOUN
admet-942	661	8	:	:	PUNCT
admet-942	661	9	from	from	ADP
admet-942	661	10	enrichment	enrichment	NOUN
admet-942	661	11	,	,	PUNCT
admet-942	661	12	release	release	NOUN
admet-942	661	13	to	to	ADP
admet-942	661	14	single	single	ADJ
admet-942	661	15	cell	cell	NOUN
admet-942	661	16	analysis	analysis	NOUN
admet-942	661	17	.	.	PUNCT
admet-942	662	1	trac	trac	NOUN
admet-942	662	2	trends	trend	NOUN
admet-942	662	3	in	in	ADP
admet-942	662	4	analytical	analytical	ADJ
admet-942	662	5	chemistry	chemistry	NOUN
admet-942	662	6	117	117	NUM
admet-942	662	7	(	(	PUNCT
admet-942	662	8	2019	2019	NUM
admet-942	662	9	)	)	PUNCT
admet-942	662	10	27	27	NUM
admet-942	662	11	-	-	SYM
admet-942	662	12	38	38	NUM
admet-942	662	13	.	.	PUNCT
admet-942	663	1	https://doi.org/10.1016/j.trac.2019.03.027	https://doi.org/10.1016/j.trac.2019.03.027	NOUN
admet-942	663	2	.	.	PUNCT
admet-942	664	1	[	[	X
admet-942	664	2	37	37	NUM
admet-942	664	3	]	]	PUNCT
admet-942	664	4	k.	k.	NOUN
admet-942	664	5	sakthivel	sakthivel	PROPN
admet-942	664	6	,	,	PUNCT
admet-942	664	7	a.	a.	PROPN
admet-942	664	8	o’brien	o’brien	PROPN
admet-942	664	9	,	,	PUNCT
admet-942	664	10	k.	k.	PROPN
admet-942	664	11	kim	kim	PROPN
admet-942	664	12	,	,	PUNCT
admet-942	664	13	m.	m.	NOUN
admet-942	664	14	hoorfar	hoorfar	PROPN
admet-942	664	15	.	.	PUNCT
admet-942	665	1	microfluidic	microfluidic	ADJ
admet-942	665	2	analysis	analysis	NOUN
admet-942	665	3	of	of	ADP
admet-942	665	4	heterotypic	heterotypic	ADJ
admet-942	665	5	cellular	cellular	ADJ
admet-942	665	6	interactions	interaction	NOUN
admet-942	665	7	:	:	PUNCT
admet-942	665	8	a	a	DET
admet-942	665	9	review	review	NOUN
admet-942	665	10	of	of	ADP
admet-942	665	11	techniques	technique	NOUN
admet-942	665	12	and	and	CCONJ
admet-942	665	13	applications	application	NOUN
admet-942	665	14	.	.	PUNCT
admet-942	666	1	trac	trac	NOUN
admet-942	666	2	trends	trend	NOUN
admet-942	666	3	in	in	ADP
admet-942	666	4	analytical	analytical	ADJ
admet-942	666	5	chemistry	chemistry	NOUN
admet-942	666	6	117	117	NUM
admet-942	666	7	(	(	PUNCT
admet-942	666	8	2019	2019	NUM
admet-942	666	9	)	)	PUNCT
admet-942	666	10	166	166	NUM
admet-942	666	11	-	-	SYM
admet-942	666	12	185	185	NUM
admet-942	666	13	.	.	PUNCT
admet-942	667	1	https://doi.org/10.1016/j.trac.2019.03.026	https://doi.org/10.1016/j.trac.2019.03.026	PROPN
admet-942	667	2	.	.	PUNCT
admet-942	668	1	[	[	X
admet-942	668	2	38	38	NUM
admet-942	668	3	]	]	X
admet-942	668	4	m.s	m.s	PROPN
admet-942	668	5	.	.	PROPN
admet-942	668	6	hall	hall	PROPN
admet-942	668	7	,	,	PUNCT
admet-942	668	8	j.t	j.t	PROPN
admet-942	668	9	.	.	PROPN
admet-942	668	10	decker	decker	PROPN
admet-942	668	11	,	,	PUNCT
admet-942	668	12	l.d	l.d	PROPN
admet-942	668	13	.	.	PROPN
admet-942	668	14	shea	shea	PROPN
admet-942	668	15	.	.	PUNCT
admet-942	669	1	towards	towards	ADP
admet-942	669	2	systems	system	NOUN
admet-942	669	3	tissue	tissue	NOUN
admet-942	669	4	engineering	engineering	NOUN
admet-942	669	5	:	:	PUNCT
admet-942	669	6	elucidating	elucidate	VERB
admet-942	669	7	the	the	DET
admet-942	669	8	dynamics	dynamic	NOUN
admet-942	669	9	,	,	PUNCT
admet-942	669	10	spatial	spatial	ADJ
admet-942	669	11	coordination	coordination	NOUN
admet-942	669	12	,	,	PUNCT
admet-942	669	13	and	and	CCONJ
admet-942	669	14	individual	individual	ADJ
admet-942	669	15	cells	cell	NOUN
admet-942	669	16	driving	drive	VERB
admet-942	669	17	emergent	emergent	ADJ
admet-942	669	18	behaviors	behavior	NOUN
admet-942	669	19	.	.	PUNCT
admet-942	670	1	biomaterials	biomaterial	NOUN
admet-942	670	2	255	255	NUM
admet-942	670	3	(	(	PUNCT
admet-942	670	4	2020	2020	NUM
admet-942	670	5	)	)	PUNCT
admet-942	670	6	120189	120189	NUM
admet-942	670	7	.	.	PUNCT
admet-942	671	1	https://doi.org/10.1016/j.biomaterials.2020.120189	https://doi.org/10.1016/j.biomaterials.2020.120189	NOUN
admet-942	671	2	.	.	PUNCT
admet-942	672	1	[	[	X
admet-942	672	2	39	39	NUM
admet-942	672	3	]	]	PUNCT
admet-942	672	4	d.	d.	PROPN
admet-942	672	5	he	he	PRON
admet-942	672	6	,	,	PUNCT
admet-942	672	7	h.	h.	PROPN
admet-942	672	8	li	li	PROPN
admet-942	672	9	.	.	PROPN
admet-942	672	10	biomaterials	biomaterial	NOUN
admet-942	672	11	affect	affect	VERB
admet-942	672	12	cell	cell	NOUN
admet-942	672	13	-	-	PUNCT
admet-942	672	14	cell	cell	NOUN
admet-942	672	15	interactions	interaction	NOUN
admet-942	672	16	in	in	ADP
admet-942	672	17	vitro	vitro	X
admet-942	672	18	in	in	ADP
admet-942	672	19	tissue	tissue	NOUN
admet-942	672	20	engineering	engineering	NOUN
admet-942	672	21	.	.	PUNCT
admet-942	673	1	journal	journal	NOUN
admet-942	673	2	of	of	ADP
admet-942	673	3	materials	material	NOUN
admet-942	673	4	science	science	NOUN
admet-942	673	5	and	and	CCONJ
admet-942	673	6	technology	technology	NOUN
admet-942	673	7	63	63	NUM
admet-942	673	8	(	(	PUNCT
admet-942	673	9	2021	2021	NUM
admet-942	673	10	)	)	PUNCT
admet-942	673	11	62	62	NUM
admet-942	673	12	-	-	SYM
admet-942	673	13	72	72	NUM
admet-942	673	14	.	.	PUNCT
admet-942	673	15	https://doi.org/10.1016/j.jmst.2020.03.022	https://doi.org/10.1016/j.jmst.2020.03.022	NOUN
admet-942	673	16	.	.	PUNCT
admet-942	674	1	[	[	X
admet-942	674	2	40	40	NUM
admet-942	674	3	]	]	PUNCT
admet-942	674	4	m.	m.	NOUN
admet-942	674	5	khazaei	khazaei	PROPN
admet-942	674	6	,	,	PUNCT
admet-942	674	7	c.s	c.s	PROPN
admet-942	674	8	.	.	PROPN
admet-942	674	9	ahuja	ahuja	PROPN
admet-942	674	10	,	,	PUNCT
admet-942	674	11	m.g	m.g	PROPN
admet-942	674	12	.	.	PROPN
admet-942	674	13	fehlings	fehling	NOUN
admet-942	674	14	.	.	PUNCT
admet-942	675	1	induced	induce	VERB
admet-942	675	2	pluripotent	pluripotent	ADJ
admet-942	675	3	stem	stem	NOUN
admet-942	675	4	cells	cell	NOUN
admet-942	675	5	for	for	ADP
admet-942	675	6	traumatic	traumatic	ADJ
admet-942	675	7	spinal	spinal	NOUN
admet-942	675	8	cord	cord	NOUN
admet-942	675	9	injury	injury	NOUN
admet-942	675	10	.	.	PUNCT
admet-942	676	1	frontiers	frontier	NOUN
admet-942	676	2	in	in	ADP
admet-942	676	3	cell	cell	NOUN
admet-942	676	4	and	and	CCONJ
admet-942	676	5	developmental	developmental	ADJ
admet-942	676	6	biology	biology	NOUN
admet-942	676	7	4	4	NUM
admet-942	676	8	(	(	PUNCT
admet-942	676	9	2017	2017	NUM
admet-942	676	10	)	)	PUNCT
admet-942	676	11	1	1	NUM
admet-942	676	12	-	-	SYM
admet-942	676	13	9	9	NUM
admet-942	676	14	.	.	PUNCT
admet-942	677	1	https://doi.org/10.3389/fcell.2016.00152	https://doi.org/10.3389/fcell.2016.00152	PROPN
admet-942	677	2	.	.	PUNCT
admet-942	678	1	[	[	X
admet-942	678	2	41	41	NUM
admet-942	678	3	]	]	X
admet-942	678	4	j.h	j.h	PROPN
admet-942	678	5	.	.	PROPN
admet-942	678	6	sung	sung	PROPN
admet-942	678	7	,	,	PUNCT
admet-942	678	8	y.i	y.i	PROPN
admet-942	678	9	.	.	PROPN
admet-942	678	10	wang	wang	PROPN
admet-942	678	11	,	,	PUNCT
admet-942	678	12	n.	n.	PROPN
admet-942	678	13	narasimhan	narasimhan	PROPN
admet-942	678	14	sriram	sriram	PROPN
admet-942	678	15	,	,	PUNCT
admet-942	678	16	m.	m.	PROPN
admet-942	678	17	jackson	jackson	PROPN
admet-942	678	18	,	,	PUNCT
admet-942	678	19	c.	c.	PROPN
admet-942	678	20	long	long	PROPN
admet-942	678	21	,	,	PUNCT
admet-942	678	22	j.j	j.j	PROPN
admet-942	678	23	.	.	PROPN
admet-942	678	24	hickman	hickman	PROPN
admet-942	678	25	,	,	PUNCT
admet-942	678	26	m.l	m.l	PROPN
admet-942	678	27	.	.	PROPN
admet-942	678	28	shuler	shuler	PROPN
admet-942	678	29	.	.	PUNCT
admet-942	679	1	recent	recent	ADJ
admet-942	679	2	advances	advance	NOUN
admet-942	679	3	in	in	ADP
admet-942	679	4	body	body	NOUN
admet-942	679	5	-	-	PUNCT
admet-942	679	6	on	on	ADP
admet-942	679	7	-	-	PUNCT
admet-942	679	8	a	a	DET
admet-942	679	9	-	-	PUNCT
admet-942	679	10	chip	chip	NOUN
admet-942	679	11	systems	system	NOUN
admet-942	679	12	.	.	PUNCT
admet-942	680	1	analytical	analytical	ADJ
admet-942	680	2	chemistry	chemistry	NOUN
admet-942	680	3	91	91	NUM
admet-942	680	4	(	(	PUNCT
admet-942	680	5	2019	2019	NUM
admet-942	680	6	)	)	PUNCT
admet-942	680	7	330	330	NUM
admet-942	680	8	-	-	SYM
admet-942	680	9	351	351	NUM
admet-942	680	10	.	.	PUNCT
admet-942	681	1	https://doi.org/10.1021/acs.analchem.8b05293	https://doi.org/10.1021/acs.analchem.8b05293	X
admet-942	681	2	.	.	PUNCT
admet-942	682	1	[	[	X
admet-942	682	2	42	42	NUM
admet-942	682	3	]	]	X
admet-942	682	4	s.h	s.h	PROPN
admet-942	682	5	.	.	PROPN
admet-942	682	6	lee	lee	PROPN
admet-942	682	7	,	,	PUNCT
admet-942	682	8	b.h	b.h	PROPN
admet-942	682	9	.	.	PUNCT
admet-942	682	10	jun	jun	PROPN
admet-942	682	11	.	.	PROPN
admet-942	682	12	advances	advance	NOUN
admet-942	682	13	in	in	ADP
admet-942	682	14	dynamic	dynamic	ADJ
admet-942	682	15	microphysiological	microphysiological	ADJ
admet-942	682	16	organ	organ	NOUN
admet-942	682	17	-	-	PUNCT
admet-942	682	18	on	on	ADP
admet-942	682	19	-	-	PUNCT
admet-942	682	20	a	a	DET
admet-942	682	21	-	-	PUNCT
admet-942	682	22	chip	chip	NOUN
admet-942	682	23	:	:	PUNCT
admet-942	682	24	design	design	NOUN
admet-942	682	25	principle	principle	NOUN
admet-942	682	26	and	and	CCONJ
admet-942	682	27	its	its	PRON
admet-942	682	28	biomedical	biomedical	ADJ
admet-942	682	29	application	application	NOUN
admet-942	682	30	.	.	PUNCT
admet-942	683	1	journal	journal	PROPN
admet-942	683	2	of	of	ADP
admet-942	683	3	industrial	industrial	ADJ
admet-942	683	4	and	and	CCONJ
admet-942	683	5	engineering	engineer	VERB
admet-942	683	6	chemistry	chemistry	NOUN
admet-942	683	7	71	71	NUM
admet-942	683	8	(	(	PUNCT
admet-942	683	9	2019	2019	NUM
admet-942	683	10	)	)	PUNCT
admet-942	683	11	65	65	NUM
admet-942	683	12	-	-	SYM
admet-942	683	13	77	77	NUM
admet-942	683	14	.	.	PUNCT
admet-942	684	1	https://doi.org/10.1016/j.jiec.2018.11.041	https://doi.org/10.1016/j.jiec.2018.11.041	NOUN
admet-942	684	2	.	.	PUNCT
admet-942	685	1	[	[	X
admet-942	685	2	43	43	NUM
admet-942	685	3	]	]	PUNCT
admet-942	685	4	z.	z.	PROPN
admet-942	685	5	jia	jia	PROPN
admet-942	685	6	,	,	PUNCT
admet-942	685	7	y.	y.	PROPN
admet-942	685	8	cheng	cheng	PROPN
admet-942	685	9	,	,	PUNCT
admet-942	685	10	x.	x.	PROPN
admet-942	685	11	jiang	jiang	PROPN
admet-942	685	12	,	,	PUNCT
admet-942	685	13	c.	c.	PROPN
admet-942	685	14	zhang	zhang	PROPN
admet-942	685	15	,	,	PUNCT
admet-942	685	16	g.	g.	PROPN
admet-942	685	17	wang	wang	PROPN
admet-942	685	18	.	.	PUNCT
admet-942	686	1	3d	3d	NUM
admet-942	686	2	culture	culture	NOUN
admet-942	686	3	system	system	NOUN
admet-942	686	4	for	for	ADP
admet-942	686	5	liver	liver	NOUN
admet-942	686	6	tissue	tissue	NOUN
admet-942	686	7	mimicking	mimic	VERB
admet-942	686	8	hepatic	hepatic	ADJ
admet-942	686	9	plates	plate	NOUN
admet-942	686	10	for	for	ADP
admet-942	686	11	improvement	improvement	NOUN
admet-942	686	12	of	of	ADP
admet-942	686	13	human	human	ADJ
admet-942	686	14	hepatocyte	hepatocyte	NOUN
admet-942	686	15	(	(	PUNCT
admet-942	686	16	c3a	c3a	PROPN
admet-942	686	17	)	)	PUNCT
admet-942	686	18	function	function	NOUN
admet-942	686	19	and	and	CCONJ
admet-942	686	20	polarity	polarity	NOUN
admet-942	686	21	.	.	PUNCT
admet-942	686	22	biomed	biome	VERB
admet-942	686	23	research	research	NOUN
admet-942	686	24	international	international	ADJ
admet-942	686	25	(	(	PUNCT
admet-942	686	26	2020	2020	NUM
admet-942	686	27	)	)	PUNCT
admet-942	686	28	.	.	PUNCT
admet-942	687	1	https://doi.org/10.1155/2020/6354183	https://doi.org/10.1155/2020/6354183	PROPN
admet-942	687	2	.	.	PUNCT
admet-942	688	1	https://doi.org/10.1002/smll.201503208	https://doi.org/10.1002/smll.201503208	ADJ
admet-942	688	2	https://doi.org/10.1016/j.mee.2018.08.004	https://doi.org/10.1016/j.mee.2018.08.004	ADJ
admet-942	688	3	https://doi.org/10.1016/j.cobme.2017.02.002	https://doi.org/10.1016/j.cobme.2017.02.002	NOUN
admet-942	688	4	https://doi.org/10.1016/j.cobme.2017.02.002	https://doi.org/10.1016/j.cobme.2017.02.002	NOUN
admet-942	688	5	https://doi.org/10.1242/dev.156125	https://doi.org/10.1242/dev.156125	PROPN
admet-942	688	6	https://doi.org/10.1016/j.cotox.2019.08.004	https://doi.org/10.1016/j.cotox.2019.08.004	PROPN
admet-942	688	7	https://doi.org/10.1016/j.drudis.2019.03.025	https://doi.org/10.1016/j.drudis.2019.03.025	PROPN
admet-942	688	8	https://doi.org/10.1016/j.coche.2019.10.006	https://doi.org/10.1016/j.coche.2019.10.006	PROPN
admet-942	688	9	https://doi.org/10.1016/j.trac.2019.03.027	https://doi.org/10.1016/j.trac.2019.03.027	PROPN
admet-942	688	10	https://doi.org/10.1016/j.trac.2019.03.026	https://doi.org/10.1016/j.trac.2019.03.026	PROPN
admet-942	688	11	https://doi.org/10.1016/j.biomaterials.2020.120189	https://doi.org/10.1016/j.biomaterials.2020.120189	ADJ
admet-942	688	12	https://doi.org/10.1016/j.jmst.2020.03.022	https://doi.org/10.1016/j.jmst.2020.03.022	NOUN
admet-942	688	13	https://doi.org/10.3389/fcell.2016.00152	https://doi.org/10.3389/fcell.2016.00152	PROPN
admet-942	688	14	https://doi.org/10.1016/j.jiec.2018.11.041	https://doi.org/10.1016/j.jiec.2018.11.041	NOUN
admet-942	688	15	https://doi.org/10.1155/2020/6354183	https://doi.org/10.1155/2020/6354183	NOUN
admet-942	688	16	admet	admet	PROPN
admet-942	688	17	&	&	CCONJ
admet-942	688	18	dmpk	dmpk	PROPN
admet-942	688	19	9(2	9(2	NUM
admet-942	688	20	)	)	PUNCT
admet-942	688	21	(	(	PUNCT
admet-942	688	22	2021	2021	NUM
admet-942	688	23	)	)	PUNCT
admet-942	688	24	111	111	NUM
admet-942	688	25	-	-	SYM
admet-942	688	26	141	141	NUM
admet-942	688	27	organ	organ	NOUN
admet-942	688	28	-	-	PUNCT
admet-942	688	29	on	on	ADP
admet-942	688	30	-	-	PUNCT
admet-942	688	31	a	a	DET
admet-942	688	32	-	-	PUNCT
admet-942	688	33	chip	chip	NOUN
admet-942	688	34	systems	system	NOUN
admet-942	688	35	for	for	ADP
admet-942	688	36	new	new	ADJ
admet-942	688	37	drugs	drug	NOUN
admet-942	688	38	development	development	NOUN
admet-942	688	39	doi	doi	PROPN
admet-942	688	40	:	:	PUNCT
admet-942	688	41	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	NOUN
admet-942	688	42	135	135	NUM
admet-942	688	43	[	[	SYM
admet-942	688	44	44	44	NUM
admet-942	688	45	]	]	PUNCT
admet-942	688	46	k.	k.	PROPN
admet-942	688	47	gold	gold	PROPN
admet-942	688	48	,	,	PUNCT
admet-942	688	49	a.k	a.k	PROPN
admet-942	688	50	.	.	PROPN
admet-942	688	51	gaharwar	gaharwar	PROPN
admet-942	688	52	,	,	PUNCT
admet-942	688	53	a.	a.	NOUN
admet-942	688	54	jain	jain	PROPN
admet-942	688	55	.	.	PUNCT
admet-942	689	1	emerging	emerge	VERB
admet-942	689	2	trends	trend	NOUN
admet-942	689	3	in	in	ADP
admet-942	689	4	multiscale	multiscale	ADJ
admet-942	689	5	modeling	modeling	NOUN
admet-942	689	6	of	of	ADP
admet-942	689	7	vascular	vascular	ADJ
admet-942	689	8	pathophysiology	pathophysiology	NOUN
admet-942	689	9	:	:	PUNCT
admet-942	689	10	organ	organ	NOUN
admet-942	689	11	-	-	PUNCT
admet-942	689	12	on	on	ADP
admet-942	689	13	-	-	PUNCT
admet-942	689	14	a	a	DET
admet-942	689	15	-	-	PUNCT
admet-942	689	16	chip	chip	NOUN
admet-942	689	17	and	and	CCONJ
admet-942	689	18	3d	3d	NUM
admet-942	689	19	printing	printing	NOUN
admet-942	689	20	.	.	PUNCT
admet-942	690	1	biomaterials	biomaterial	NOUN
admet-942	690	2	196	196	NUM
admet-942	690	3	(	(	PUNCT
admet-942	690	4	2019	2019	NUM
admet-942	690	5	)	)	PUNCT
admet-942	690	6	2	2	NUM
admet-942	690	7	-	-	SYM
admet-942	690	8	17	17	NUM
admet-942	690	9	.	.	PUNCT
admet-942	691	1	https://doi.org/10.1016/j.biomaterials.2018.07.029	https://doi.org/10.1016/j.biomaterials.2018.07.029	PROPN
admet-942	691	2	.	.	PUNCT
admet-942	692	1	[	[	X
admet-942	692	2	45	45	NUM
admet-942	692	3	]	]	PUNCT
admet-942	692	4	j.	j.	PROPN
admet-942	692	5	wang	wang	PROPN
admet-942	692	6	,	,	PUNCT
admet-942	692	7	c.	c.	PROPN
admet-942	692	8	wang	wang	PROPN
admet-942	692	9	,	,	PUNCT
admet-942	692	10	n.	n.	PROPN
admet-942	692	11	xu	xu	PROPN
admet-942	692	12	,	,	PUNCT
admet-942	692	13	z.f	z.f	PROPN
admet-942	692	14	.	.	PROPN
admet-942	692	15	liu	liu	PROPN
admet-942	692	16	,	,	PUNCT
admet-942	692	17	d.w	d.w	PROPN
admet-942	692	18	.	.	PROPN
admet-942	692	19	pang	pang	NOUN
admet-942	692	20	,	,	PUNCT
admet-942	692	21	z.l	z.l	PROPN
admet-942	692	22	.	.	PROPN
admet-942	692	23	zhang	zhang	PROPN
admet-942	692	24	.	.	PUNCT
admet-942	693	1	a	a	DET
admet-942	693	2	virus	virus	NOUN
admet-942	693	3	-	-	PUNCT
admet-942	693	4	induced	induce	VERB
admet-942	693	5	kidney	kidney	NOUN
admet-942	693	6	disease	disease	NOUN
admet-942	693	7	model	model	NOUN
admet-942	693	8	based	base	VERB
admet-942	693	9	on	on	ADP
admet-942	693	10	organ	organ	NOUN
admet-942	693	11	-	-	PUNCT
admet-942	693	12	on	on	ADP
admet-942	693	13	-	-	PUNCT
admet-942	693	14	a	a	DET
admet-942	693	15	-	-	PUNCT
admet-942	693	16	chip	chip	NOUN
admet-942	693	17	:	:	PUNCT
admet-942	693	18	pathogenesis	pathogenesis	NOUN
admet-942	693	19	exploration	exploration	NOUN
admet-942	693	20	of	of	ADP
admet-942	693	21	virus	virus	NOUN
admet-942	693	22	-	-	PUNCT
admet-942	693	23	related	relate	VERB
admet-942	693	24	renal	renal	ADJ
admet-942	693	25	dysfunctions	dysfunction	NOUN
admet-942	693	26	.	.	PUNCT
admet-942	694	1	biomaterials	biomaterial	NOUN
admet-942	694	2	219	219	NUM
admet-942	694	3	(	(	PUNCT
admet-942	694	4	2019	2019	NUM
admet-942	694	5	)	)	PUNCT
admet-942	694	6	.	.	PUNCT
admet-942	695	1	https://doi.org/10.1016/j.biomaterials.2019.119367	https://doi.org/10.1016/j.biomaterials.2019.119367	PROPN
admet-942	695	2	.	.	PUNCT
admet-942	696	1	[	[	X
admet-942	696	2	46	46	NUM
admet-942	696	3	]	]	PUNCT
admet-942	696	4	a.	a.	NOUN
admet-942	696	5	moya	moya	PROPN
admet-942	696	6	,	,	PUNCT
admet-942	696	7	m.	m.	PROPN
admet-942	696	8	ortega	ortega	PROPN
admet-942	696	9	-	-	PUNCT
admet-942	696	10	ribera	ribera	PROPN
admet-942	696	11	,	,	PUNCT
admet-942	696	12	x.	x.	NOUN
admet-942	696	13	guimerà	guimerà	PROPN
admet-942	696	14	,	,	PUNCT
admet-942	696	15	e.	e.	PROPN
admet-942	696	16	sowade	sowade	PROPN
admet-942	696	17	,	,	PUNCT
admet-942	696	18	m.	m.	NOUN
admet-942	696	19	zea	zea	PROPN
admet-942	696	20	,	,	PUNCT
admet-942	696	21	x.	x.	NOUN
admet-942	696	22	illa	illa	PROPN
admet-942	696	23	,	,	PUNCT
admet-942	696	24	e.	e.	PROPN
admet-942	696	25	ramon	ramon	PROPN
admet-942	696	26	,	,	PUNCT
admet-942	696	27	r.	r.	PROPN
admet-942	696	28	villa	villa	PROPN
admet-942	696	29	,	,	PUNCT
admet-942	696	30	j.	j.	PROPN
admet-942	696	31	graciasancho	graciasancho	PROPN
admet-942	696	32	,	,	PUNCT
admet-942	696	33	g.	g.	PROPN
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admet-942	696	35	.	.	PUNCT
admet-942	697	1	online	online	ADJ
admet-942	697	2	oxygen	oxygen	NOUN
admet-942	697	3	monitoring	monitoring	NOUN
admet-942	697	4	using	use	VERB
admet-942	697	5	integrated	integrated	ADJ
admet-942	697	6	inkjet	inkjet	NOUN
admet-942	697	7	-	-	PUNCT
admet-942	697	8	printed	print	VERB
admet-942	697	9	sensors	sensor	NOUN
admet-942	697	10	in	in	ADP
admet-942	697	11	a	a	DET
admet-942	697	12	liver	liver	NOUN
admet-942	697	13	-	-	PUNCT
admet-942	697	14	on	on	ADP
admet-942	697	15	-	-	PUNCT
admet-942	697	16	achip	achip	NOUN
admet-942	697	17	system	system	NOUN
admet-942	697	18	.	.	PUNCT
admet-942	698	1	lab	lab	NOUN
admet-942	698	2	on	on	ADP
admet-942	698	3	a	a	DET
admet-942	698	4	chip	chip	NOUN
admet-942	698	5	18	18	NUM
admet-942	698	6	(	(	PUNCT
admet-942	698	7	2018	2018	NUM
admet-942	698	8	)	)	PUNCT
admet-942	698	9	2023	2023	NUM
admet-942	698	10	-	-	SYM
admet-942	698	11	2035	2035	NUM
admet-942	698	12	.	.	PUNCT
admet-942	699	1	https://doi.org/10.1039/c8lc00456k	https://doi.org/10.1039/c8lc00456k	PROPN
admet-942	699	2	.	.	PUNCT
admet-942	700	1	[	[	X
admet-942	700	2	47	47	NUM
admet-942	700	3	]	]	X
admet-942	700	4	n.	n.	PROPN
admet-942	700	5	torras	torras	PROPN
admet-942	700	6	,	,	PUNCT
admet-942	700	7	m.	m.	NOUN
admet-942	700	8	garcía	garcía	NOUN
admet-942	700	9	-	-	PUNCT
admet-942	700	10	díaz	díaz	NOUN
admet-942	700	11	,	,	PUNCT
admet-942	700	12	v.	v.	ADP
admet-942	700	13	fernández	fernández	PROPN
admet-942	700	14	-	-	PUNCT
admet-942	700	15	majada	majada	PROPN
admet-942	700	16	,	,	PUNCT
admet-942	700	17	e.	e.	PROPN
admet-942	700	18	martínez	martínez	PROPN
admet-942	700	19	.	.	PUNCT
admet-942	700	20	mimicking	mimic	VERB
admet-942	700	21	epithelial	epithelial	ADJ
admet-942	700	22	tissues	tissue	NOUN
admet-942	700	23	in	in	ADP
admet-942	700	24	threedimensional	threedimensional	ADJ
admet-942	700	25	cell	cell	NOUN
admet-942	700	26	culture	culture	NOUN
admet-942	700	27	models	model	NOUN
admet-942	700	28	.	.	PUNCT
admet-942	701	1	frontiers	frontier	NOUN
admet-942	701	2	in	in	ADP
admet-942	701	3	bioengineering	bioengineering	NOUN
admet-942	701	4	and	and	CCONJ
admet-942	701	5	biotechnology	biotechnology	NOUN
admet-942	701	6	6	6	NUM
admet-942	701	7	(	(	PUNCT
admet-942	701	8	2018	2018	NUM
admet-942	701	9	)	)	PUNCT
admet-942	701	10	1	1	NUM
admet-942	701	11	-	-	SYM
admet-942	701	12	7	7	NUM
admet-942	701	13	.	.	PUNCT
admet-942	702	1	https://doi.org/10.3389/fbioe.2018.00197	https://doi.org/10.3389/fbioe.2018.00197	NOUN
admet-942	702	2	.	.	PUNCT
admet-942	703	1	[	[	X
admet-942	703	2	48	48	NUM
admet-942	703	3	]	]	X
admet-942	703	4	g.	g.	PROPN
admet-942	703	5	adriani	adriani	PROPN
admet-942	703	6	,	,	PUNCT
admet-942	703	7	d.	d.	PROPN
admet-942	703	8	ma	ma	PROPN
admet-942	703	9	,	,	PUNCT
admet-942	703	10	a.	a.	NOUN
admet-942	703	11	pavesi	pavesi	PROPN
admet-942	703	12	,	,	PUNCT
admet-942	703	13	r.d	r.d	PROPN
admet-942	703	14	.	.	PROPN
admet-942	703	15	kamm	kamm	PROPN
admet-942	703	16	,	,	PUNCT
admet-942	703	17	e.l.k	e.l.k	PROPN
admet-942	703	18	.	.	PUNCT
admet-942	704	1	goh	goh	PROPN
admet-942	704	2	.	.	PUNCT
admet-942	705	1	a	a	DET
admet-942	705	2	3d	3d	NUM
admet-942	705	3	neurovascular	neurovascular	ADJ
admet-942	705	4	microfluidic	microfluidic	ADJ
admet-942	705	5	model	model	NOUN
admet-942	705	6	consisting	consist	VERB
admet-942	705	7	of	of	ADP
admet-942	705	8	neurons	neuron	NOUN
admet-942	705	9	,	,	PUNCT
admet-942	705	10	astrocytes	astrocyte	NOUN
admet-942	705	11	and	and	CCONJ
admet-942	705	12	cerebral	cerebral	ADJ
admet-942	705	13	endothelial	endothelial	ADJ
admet-942	705	14	cells	cell	NOUN
admet-942	705	15	as	as	ADP
admet-942	705	16	a	a	DET
admet-942	705	17	blood	blood	NOUN
admet-942	705	18	-	-	PUNCT
admet-942	705	19	brain	brain	NOUN
admet-942	705	20	barrier	barrier	NOUN
admet-942	705	21	.	.	PUNCT
admet-942	706	1	lab	lab	NOUN
admet-942	706	2	on	on	ADP
admet-942	706	3	a	a	DET
admet-942	706	4	chip	chip	NOUN
admet-942	706	5	17	17	NUM
admet-942	706	6	(	(	PUNCT
admet-942	706	7	2017	2017	NUM
admet-942	706	8	)	)	PUNCT
admet-942	706	9	448	448	NUM
admet-942	706	10	-	-	SYM
admet-942	706	11	459	459	NUM
admet-942	706	12	.	.	PUNCT
admet-942	707	1	https://doi.org/10.1039/c6lc00638h	https://doi.org/10.1039/c6lc00638h	PROPN
admet-942	707	2	.	.	PUNCT
admet-942	708	1	[	[	X
admet-942	708	2	49	49	NUM
admet-942	708	3	]	]	X
admet-942	708	4	f.	f.	PROPN
admet-942	708	5	yu	yu	PROPN
admet-942	708	6	,	,	PUNCT
admet-942	708	7	w.	w.	PROPN
admet-942	708	8	hunziker	hunziker	PROPN
admet-942	708	9	,	,	PUNCT
admet-942	708	10	d.	d.	PROPN
admet-942	708	11	choudhury	choudhury	PROPN
admet-942	708	12	.	.	PUNCT
admet-942	709	1	engineering	engineer	VERB
admet-942	709	2	microfluidic	microfluidic	ADJ
admet-942	709	3	organoid	organoid	NOUN
admet-942	709	4	-	-	PUNCT
admet-942	709	5	on	on	ADP
admet-942	709	6	-	-	PUNCT
admet-942	709	7	a	a	DET
admet-942	709	8	-	-	PUNCT
admet-942	709	9	chip	chip	NOUN
admet-942	709	10	platforms	platform	NOUN
admet-942	709	11	.	.	PUNCT
admet-942	710	1	micromachines	micromachine	NOUN
admet-942	710	2	10	10	NUM
admet-942	710	3	(	(	PUNCT
admet-942	710	4	2019	2019	NUM
admet-942	710	5	)	)	PUNCT
admet-942	710	6	1	1	NUM
admet-942	710	7	-	-	SYM
admet-942	710	8	12	12	NUM
admet-942	710	9	.	.	PUNCT
admet-942	711	1	https://doi.org/10.3390/mi10030165	https://doi.org/10.3390/mi10030165	NOUN
admet-942	711	2	.	.	PUNCT
admet-942	712	1	[	[	X
admet-942	712	2	50	50	NUM
admet-942	712	3	]	]	X
admet-942	712	4	k.a	k.a	PROPN
admet-942	712	5	.	.	PROPN
admet-942	712	6	sun	sun	PROPN
admet-942	712	7	w	w	PROPN
admet-942	712	8	,	,	PUNCT
admet-942	712	9	luo	luo	PROPN
admet-942	712	10	z	z	PROPN
admet-942	712	11	,	,	PUNCT
admet-942	712	12	lee	lee	PROPN
admet-942	712	13	j	j	PROPN
admet-942	712	14	,	,	PUNCT
admet-942	712	15	kim	kim	PROPN
admet-942	712	16	hj	hj	PROPN
admet-942	712	17	,	,	PUNCT
admet-942	712	18	lee	lee	PROPN
admet-942	712	19	k	k	PROPN
admet-942	712	20	,	,	PUNCT
admet-942	712	21	tebon	tebon	PROPN
admet-942	712	22	p	p	X
admet-942	712	23	,	,	PUNCT
admet-942	712	24	feng	feng	PROPN
admet-942	712	25	y	y	PROPN
admet-942	712	26	,	,	PUNCT
admet-942	712	27	dokmec	dokmec	PROPN
admet-942	712	28	,	,	PUNCT
admet-942	712	29	m	m	PROPN
admet-942	712	30	,	,	PUNCT
admet-942	712	31	sengupta	sengupta	NOUN
admet-942	712	32	s.	s.	PROPN
admet-942	712	33	organ	organ	PROPN
admet-942	712	34	-	-	PUNCT
admet-942	712	35	on	on	ADP
admet-942	712	36	-	-	PUNCT
admet-942	712	37	a	a	DET
admet-942	712	38	-	-	PUNCT
admet-942	712	39	chip	chip	NOUN
admet-942	712	40	for	for	ADP
admet-942	712	41	cancer	cancer	NOUN
admet-942	712	42	and	and	CCONJ
admet-942	712	43	immune	immune	ADJ
admet-942	712	44	organs	organ	NOUN
admet-942	712	45	modeling	model	VERB
admet-942	712	46	.	.	PUNCT
admet-942	713	1	adv	adv	PROPN
admet-942	713	2	healthc	healthc	PROPN
admet-942	713	3	mater	mater	PROPN
admet-942	713	4	.	.	PROPN
admet-942	713	5	8	8	NUM
admet-942	713	6	(	(	PUNCT
admet-942	713	7	2019	2019	NUM
admet-942	713	8	)	)	PUNCT
admet-942	713	9	139	139	NUM
admet-942	713	10	-	-	SYM
admet-942	713	11	148	148	NUM
admet-942	713	12	.	.	PUNCT
admet-942	714	1	doi	doi	NOUN
admet-942	714	2	:	:	PUNCT
admet-942	714	3	https://doi.org/10.1002/adhm.201801363	https://doi.org/10.1002/adhm.201801363	X
admet-942	714	4	.	.	PUNCT
admet-942	715	1	[	[	X
admet-942	715	2	51	51	NUM
admet-942	715	3	]	]	X
admet-942	715	4	t.m	t.m	PROPN
admet-942	715	5	.	.	PROPN
admet-942	715	6	marin	marin	PROPN
admet-942	715	7	,	,	PUNCT
admet-942	715	8	n.	n.	PROPN
admet-942	715	9	de	de	PROPN
admet-942	715	10	carvalho	carvalho	PROPN
admet-942	715	11	indolfo	indolfo	PROPN
admet-942	715	12	,	,	PUNCT
admet-942	715	13	s.a	s.a	PROPN
admet-942	715	14	.	.	PROPN
admet-942	715	15	rocco	rocco	PROPN
admet-942	715	16	,	,	PUNCT
admet-942	715	17	f.l	f.l	PROPN
admet-942	715	18	.	.	PROPN
admet-942	715	19	basei	basei	PROPN
admet-942	715	20	,	,	PUNCT
admet-942	715	21	m.	m.	NOUN
admet-942	715	22	de	de	PROPN
admet-942	715	23	carvalho	carvalho	PROPN
admet-942	715	24	,	,	PUNCT
admet-942	715	25	k.	k.	PROPN
admet-942	715	26	de	de	PROPN
admet-942	715	27	almeida	almeida	PROPN
admet-942	715	28	gonçalves	gonçalves	PROPN
admet-942	715	29	,	,	PUNCT
admet-942	715	30	e.	e.	PROPN
admet-942	715	31	pagani	pagani	PROPN
admet-942	715	32	.	.	PUNCT
admet-942	716	1	acetaminophen	acetaminophen	NOUN
admet-942	716	2	absorption	absorption	NOUN
admet-942	716	3	and	and	CCONJ
admet-942	716	4	metabolism	metabolism	NOUN
admet-942	716	5	in	in	ADP
admet-942	716	6	an	an	DET
admet-942	716	7	intestine	intestine	NOUN
admet-942	716	8	/	/	SYM
admet-942	716	9	liver	liver	NOUN
admet-942	716	10	microphysiological	microphysiological	ADJ
admet-942	716	11	system	system	NOUN
admet-942	716	12	.	.	PUNCT
admet-942	717	1	chemico	chemico	ADJ
admet-942	717	2	-	-	ADJ
admet-942	717	3	biological	biological	ADJ
admet-942	717	4	interactions	interaction	NOUN
admet-942	717	5	299	299	NUM
admet-942	717	6	(	(	PUNCT
admet-942	717	7	2019	2019	NUM
admet-942	717	8	)	)	PUNCT
admet-942	717	9	59	59	NUM
admet-942	717	10	-	-	SYM
admet-942	717	11	76	76	NUM
admet-942	717	12	.	.	PUNCT
admet-942	718	1	https://doi.org/10.1016/j.cbi.2018.11.010	https://doi.org/10.1016/j.cbi.2018.11.010	NOUN
admet-942	718	2	.	.	PUNCT
admet-942	719	1	[	[	X
admet-942	719	2	52	52	NUM
admet-942	719	3	]	]	X
admet-942	719	4	d.e	d.e	PROPN
admet-942	719	5	.	.	PROPN
admet-942	719	6	ingber	ingber	PROPN
admet-942	719	7	.	.	PUNCT
admet-942	720	1	reverse	reverse	VERB
admet-942	720	2	engineering	engineer	VERB
admet-942	720	3	human	human	ADJ
admet-942	720	4	pathophysiology	pathophysiology	NOUN
admet-942	720	5	with	with	ADP
admet-942	720	6	organs	organ	NOUN
admet-942	720	7	-	-	PUNCT
admet-942	720	8	on	on	ADP
admet-942	720	9	-	-	PUNCT
admet-942	720	10	chips	chip	NOUN
admet-942	720	11	.	.	PUNCT
admet-942	721	1	cell	cell	NOUN
admet-942	721	2	164	164	NUM
admet-942	721	3	(	(	PUNCT
admet-942	721	4	2016	2016	NUM
admet-942	721	5	)	)	PUNCT
admet-942	721	6	1105	1105	NUM
admet-942	721	7	-	-	SYM
admet-942	721	8	1109	1109	NUM
admet-942	721	9	.	.	PUNCT
admet-942	722	1	https://doi.org/10.1016/j.cell.2016.02.049	https://doi.org/10.1016/j.cell.2016.02.049	NOUN
admet-942	722	2	.	.	PUNCT
admet-942	723	1	[	[	X
admet-942	723	2	53	53	NUM
admet-942	723	3	]	]	PUNCT
admet-942	723	4	j.	j.	PROPN
admet-942	723	5	shi	shi	PROPN
admet-942	723	6	,	,	PUNCT
admet-942	723	7	l.	l.	PROPN
admet-942	723	8	tong	tong	PROPN
admet-942	723	9	,	,	PUNCT
admet-942	723	10	w.	w.	PROPN
admet-942	723	11	tong	tong	PROPN
admet-942	723	12	,	,	PUNCT
admet-942	723	13	h.	h.	PROPN
admet-942	723	14	chen	chen	PROPN
admet-942	723	15	,	,	PUNCT
admet-942	723	16	m.	m.	PROPN
admet-942	723	17	lan	lan	PROPN
admet-942	723	18	,	,	PUNCT
admet-942	723	19	x.	x.	PROPN
admet-942	723	20	sun	sun	PROPN
admet-942	723	21	,	,	PUNCT
admet-942	723	22	y.	y.	PROPN
admet-942	723	23	zhu	zhu	PROPN
admet-942	723	24	.	.	PUNCT
admet-942	724	1	current	current	ADJ
admet-942	724	2	progress	progress	NOUN
admet-942	724	3	in	in	ADP
admet-942	724	4	long	long	ADJ
admet-942	724	5	-	-	PUNCT
admet-942	724	6	term	term	NOUN
admet-942	724	7	and	and	CCONJ
admet-942	724	8	continuous	continuous	ADJ
admet-942	724	9	cell	cell	NOUN
admet-942	724	10	metabolite	metabolite	NOUN
admet-942	724	11	detection	detection	NOUN
admet-942	724	12	using	use	VERB
admet-942	724	13	microfluidics	microfluidic	NOUN
admet-942	724	14	.	.	PUNCT
admet-942	725	1	trac	trac	NOUN
admet-942	725	2	trends	trend	NOUN
admet-942	725	3	in	in	ADP
admet-942	725	4	analytical	analytical	ADJ
admet-942	725	5	chemistry	chemistry	NOUN
admet-942	725	6	117	117	NUM
admet-942	725	7	(	(	PUNCT
admet-942	725	8	2019	2019	NUM
admet-942	725	9	)	)	PUNCT
admet-942	725	10	263279	263279	NUM
admet-942	725	11	.	.	PUNCT
admet-942	726	1	https://doi.org/10.1016/j.trac.2019.05.028	https://doi.org/10.1016/j.trac.2019.05.028	PROPN
admet-942	726	2	.	.	PUNCT
admet-942	727	1	[	[	X
admet-942	727	2	54	54	NUM
admet-942	727	3	]	]	PUNCT
admet-942	727	4	m.	m.	NOUN
admet-942	727	5	peters	peters	PROPN
admet-942	727	6	,	,	PUNCT
admet-942	727	7	a.	a.	NOUN
admet-942	727	8	choy	choy	NOUN
admet-942	727	9	,	,	PUNCT
admet-942	727	10	c.	c.	PROPN
admet-942	727	11	pin	pin	PROPN
admet-942	727	12	,	,	PUNCT
admet-942	727	13	d.	d.	PROPN
admet-942	727	14	leishmann	leishmann	PROPN
admet-942	727	15	,	,	PUNCT
admet-942	727	16	a.	a.	PROPN
admet-942	727	17	moisan	moisan	PROPN
admet-942	727	18	,	,	PUNCT
admet-942	727	19	l.c	l.c	PROPN
admet-942	727	20	.	.	PROPN
admet-942	727	21	ewart	ewart	PROPN
admet-942	727	22	,	,	PUNCT
admet-942	727	23	p.	p.	NOUN
admet-942	727	24	guzzie	guzzie	PROPN
admet-942	727	25	-	-	PUNCT
admet-942	727	26	peck	peck	PROPN
admet-942	727	27	,	,	PUNCT
admet-942	727	28	r.	r.	PROPN
admet-942	727	29	sura	sura	PROPN
admet-942	727	30	,	,	PUNCT
admet-942	727	31	d.	d.	PROPN
admet-942	727	32	keller	keller	PROPN
admet-942	727	33	,	,	PUNCT
admet-942	727	34	c.w	c.w	PROPN
admet-942	727	35	.	.	PROPN
admet-942	727	36	scott	scott	PROPN
admet-942	727	37	,	,	PUNCT
admet-942	727	38	k.	k.	PROPN
admet-942	727	39	kolaja	kolaja	PROPN
admet-942	727	40	.	.	PUNCT
admet-942	728	1	developing	develop	VERB
admet-942	728	2	in	in	ADP
admet-942	728	3	vitro	vitro	X
admet-942	728	4	assays	assay	NOUN
admet-942	728	5	to	to	PART
admet-942	728	6	transform	transform	VERB
admet-942	728	7	gastrointestinal	gastrointestinal	ADJ
admet-942	728	8	safety	safety	NOUN
admet-942	728	9	assessment	assessment	NOUN
admet-942	728	10	:	:	PUNCT
admet-942	728	11	potential	potential	NOUN
admet-942	728	12	for	for	ADP
admet-942	728	13	microphysiological	microphysiological	ADJ
admet-942	728	14	systems	system	NOUN
admet-942	728	15	.	.	PUNCT
admet-942	729	1	lab	lab	NOUN
admet-942	729	2	on	on	ADP
admet-942	729	3	a	a	DET
admet-942	729	4	chip	chip	NOUN
admet-942	729	5	20	20	NUM
admet-942	729	6	(	(	PUNCT
admet-942	729	7	2020	2020	NUM
admet-942	729	8	)	)	PUNCT
admet-942	729	9	1177	1177	NUM
admet-942	729	10	-	-	SYM
admet-942	729	11	1190	1190	NUM
admet-942	729	12	.	.	PUNCT
admet-942	730	1	https://doi.org/10.1039/c9lc01107b	https://doi.org/10.1039/c9lc01107b	X
admet-942	730	2	.	.	PUNCT
admet-942	731	1	[	[	X
admet-942	731	2	55	55	NUM
admet-942	731	3	]	]	PUNCT
admet-942	731	4	t.	t.	NOUN
admet-942	731	5	osaki	osaki	PROPN
admet-942	731	6	,	,	PUNCT
admet-942	731	7	v.	v.	PROPN
admet-942	731	8	sivathanu	sivathanu	PROPN
admet-942	731	9	,	,	PUNCT
admet-942	731	10	r.d	r.d	PROPN
admet-942	731	11	.	.	PROPN
admet-942	731	12	kamm	kamm	PROPN
admet-942	731	13	.	.	PUNCT
admet-942	731	14	vascularized	vascularized	ADJ
admet-942	731	15	microfluidic	microfluidic	ADJ
admet-942	731	16	organ	organ	NOUN
admet-942	731	17	-	-	PUNCT
admet-942	731	18	chips	chip	NOUN
admet-942	731	19	for	for	ADP
admet-942	731	20	drug	drug	NOUN
admet-942	731	21	screening	screening	NOUN
admet-942	731	22	,	,	PUNCT
admet-942	731	23	disease	disease	NOUN
admet-942	731	24	models	model	NOUN
admet-942	731	25	and	and	CCONJ
admet-942	731	26	tissue	tissue	NOUN
admet-942	731	27	engineering	engineering	NOUN
admet-942	731	28	.	.	PUNCT
admet-942	732	1	current	current	ADJ
admet-942	732	2	opinion	opinion	NOUN
admet-942	732	3	in	in	ADP
admet-942	732	4	biotechnology	biotechnology	NOUN
admet-942	732	5	52	52	NUM
admet-942	732	6	(	(	PUNCT
admet-942	732	7	2018	2018	NUM
admet-942	732	8	)	)	PUNCT
admet-942	732	9	116	116	NUM
admet-942	732	10	-	-	SYM
admet-942	732	11	123	123	NUM
admet-942	732	12	.	.	PUNCT
admet-942	733	1	https://doi.org/10.1016/j.copbio.2018.03.011	https://doi.org/10.1016/j.copbio.2018.03.011	NOUN
admet-942	733	2	.	.	PUNCT
admet-942	734	1	[	[	X
admet-942	734	2	56	56	NUM
admet-942	734	3	]	]	PUNCT
admet-942	734	4	d.t.t	d.t.t	NOUN
admet-942	734	5	.	.	PUNCT
admet-942	734	6	phan	phan	PROPN
admet-942	734	7	,	,	PUNCT
admet-942	734	8	r.h.f	r.h.f	ADJ
admet-942	734	9	.	.	PUNCT
admet-942	734	10	bender	bender	PROPN
admet-942	734	11	,	,	PUNCT
admet-942	734	12	j.w	j.w	PROPN
admet-942	734	13	.	.	PROPN
admet-942	734	14	andrejecsk	andrejecsk	PROPN
admet-942	734	15	,	,	PUNCT
admet-942	734	16	a.	a.	NOUN
admet-942	734	17	sobrino	sobrino	PROPN
admet-942	734	18	,	,	PUNCT
admet-942	734	19	s.j	s.j	PROPN
admet-942	734	20	.	.	PROPN
admet-942	734	21	hachey	hachey	PROPN
admet-942	734	22	,	,	PUNCT
admet-942	734	23	s.c	s.c	PROPN
admet-942	734	24	.	.	PROPN
admet-942	734	25	george	george	PROPN
admet-942	734	26	,	,	PUNCT
admet-942	734	27	c.c.w	c.c.w	PROPN
admet-942	734	28	.	.	PUNCT
admet-942	735	1	hughes	hughes	PROPN
admet-942	735	2	.	.	PUNCT
admet-942	736	1	blood	blood	NOUN
admet-942	736	2	–	–	PUNCT
admet-942	736	3	brain	brain	NOUN
admet-942	736	4	barrier	barrier	NOUN
admet-942	736	5	-	-	PUNCT
admet-942	736	6	on	on	ADP
admet-942	736	7	-	-	PUNCT
admet-942	736	8	a	a	DET
admet-942	736	9	-	-	PUNCT
admet-942	736	10	chip	chip	NOUN
admet-942	736	11	:	:	PUNCT
admet-942	736	12	microphysiological	microphysiological	ADJ
admet-942	736	13	systems	system	NOUN
admet-942	736	14	that	that	PRON
admet-942	736	15	capture	capture	VERB
admet-942	736	16	the	the	DET
admet-942	736	17	complexity	complexity	NOUN
admet-942	736	18	of	of	ADP
admet-942	736	19	the	the	DET
admet-942	736	20	blood	blood	NOUN
admet-942	736	21	–	–	PUNCT
admet-942	736	22	central	central	ADJ
admet-942	736	23	nervous	nervous	ADJ
admet-942	736	24	system	system	NOUN
admet-942	736	25	interface	interface	NOUN
admet-942	736	26	.	.	PUNCT
admet-942	737	1	experimental	experimental	ADJ
admet-942	737	2	biology	biology	NOUN
admet-942	737	3	and	and	CCONJ
admet-942	737	4	medicine	medicine	NOUN
admet-942	737	5	242	242	NUM
admet-942	737	6	(	(	PUNCT
admet-942	737	7	2017	2017	NUM
admet-942	737	8	)	)	PUNCT
admet-942	737	9	1669	1669	NUM
admet-942	737	10	-	-	SYM
admet-942	737	11	1678	1678	NUM
admet-942	737	12	.	.	PUNCT
admet-942	738	1	https://doi.org/10.1177/1535370217694100	https://doi.org/10.1177/1535370217694100	PROPN
admet-942	738	2	.	.	PUNCT
admet-942	739	1	[	[	X
admet-942	739	2	57	57	NUM
admet-942	739	3	]	]	PUNCT
admet-942	739	4	t.	t.	NOUN
admet-942	739	5	grix	grix	PROPN
admet-942	739	6	,	,	PUNCT
admet-942	739	7	a.	a.	NOUN
admet-942	739	8	ruppelt	ruppelt	PROPN
admet-942	739	9	,	,	PUNCT
admet-942	739	10	a.	a.	PROPN
admet-942	739	11	thomas	thomas	PROPN
admet-942	739	12	,	,	PUNCT
admet-942	739	13	a.k	a.k	PROPN
admet-942	739	14	.	.	PROPN
admet-942	739	15	amler	amler	PROPN
admet-942	739	16	,	,	PUNCT
admet-942	739	17	b.p	b.p	PROPN
admet-942	739	18	.	.	PUNCT
admet-942	740	1	noichl	noichl	PROPN
admet-942	740	2	,	,	PUNCT
admet-942	740	3	r.	r.	PROPN
admet-942	740	4	lauster	lauster	PROPN
admet-942	740	5	,	,	PUNCT
admet-942	740	6	l.	l.	PROPN
admet-942	740	7	kloke	kloke	PROPN
admet-942	740	8	.	.	PUNCT
admet-942	741	1	bioprinting	bioprinting	NOUN
admet-942	741	2	perfusionenabled	perfusionenable	VERB
admet-942	741	3	liver	liver	NOUN
admet-942	741	4	equivalents	equivalent	NOUN
admet-942	741	5	for	for	ADP
admet-942	741	6	advanced	advanced	ADJ
admet-942	741	7	organ	organ	NOUN
admet-942	741	8	-	-	PUNCT
admet-942	741	9	on	on	ADP
admet-942	741	10	-	-	PUNCT
admet-942	741	11	a	a	DET
admet-942	741	12	-	-	PUNCT
admet-942	741	13	chip	chip	NOUN
admet-942	741	14	applications	application	NOUN
admet-942	741	15	.	.	PUNCT
admet-942	742	1	genes	gene	NOUN
admet-942	742	2	9	9	NUM
admet-942	742	3	(	(	PUNCT
admet-942	742	4	2018	2018	NUM
admet-942	742	5	)	)	PUNCT
admet-942	742	6	.	.	PUNCT
admet-942	743	1	https://doi.org/10.3390/genes9040176	https://doi.org/10.3390/genes9040176	NOUN
admet-942	743	2	.	.	PUNCT
admet-942	744	1	[	[	X
admet-942	744	2	58	58	NUM
admet-942	744	3	]	]	X
admet-942	744	4	f.	f.	PROPN
admet-942	744	5	yu	yu	PROPN
admet-942	744	6	,	,	PUNCT
admet-942	744	7	d.	d.	PROPN
admet-942	744	8	choudhury	choudhury	PROPN
admet-942	744	9	.	.	PUNCT
admet-942	744	10	microfluidic	microfluidic	ADJ
admet-942	744	11	bioprinting	bioprinting	NOUN
admet-942	744	12	for	for	ADP
admet-942	744	13	organ	organ	NOUN
admet-942	744	14	-	-	PUNCT
admet-942	744	15	on	on	ADP
admet-942	744	16	-	-	PUNCT
admet-942	744	17	a	a	DET
admet-942	744	18	-	-	PUNCT
admet-942	744	19	chip	chip	NOUN
admet-942	744	20	models	model	NOUN
admet-942	744	21	.	.	PUNCT
admet-942	745	1	drug	drug	NOUN
admet-942	745	2	discovery	discovery	PROPN
admet-942	745	3	today	today	NOUN
admet-942	745	4	24	24	NUM
admet-942	745	5	(	(	PUNCT
admet-942	745	6	2019	2019	NUM
admet-942	745	7	)	)	PUNCT
admet-942	745	8	1248	1248	NUM
admet-942	745	9	-	-	SYM
admet-942	745	10	1257	1257	NUM
admet-942	745	11	.	.	PUNCT
admet-942	746	1	https://doi.org/10.1016/j.drudis.2019.03.025	https://doi.org/10.1016/j.drudis.2019.03.025	NUM
admet-942	746	2	.	.	PUNCT
admet-942	747	1	[	[	X
admet-942	747	2	59	59	NUM
admet-942	747	3	]	]	PUNCT
admet-942	747	4	i.	i.	PROPN
admet-942	747	5	maimouni	maimouni	PROPN
admet-942	747	6	,	,	PUNCT
admet-942	747	7	c.m	c.m	PROPN
admet-942	747	8	.	.	PROPN
admet-942	747	9	cejas	cejas	PROPN
admet-942	747	10	,	,	PUNCT
admet-942	747	11	j.	j.	PROPN
admet-942	747	12	cossy	cossy	PROPN
admet-942	747	13	,	,	PUNCT
admet-942	747	14	p.	p.	PROPN
admet-942	747	15	tabeling	tabeling	PROPN
admet-942	747	16	,	,	PUNCT
admet-942	747	17	m.	m.	NOUN
admet-942	747	18	russo	russo	PROPN
admet-942	747	19	.	.	PUNCT
admet-942	748	1	microfluidics	microfluidic	NOUN
admet-942	748	2	mediated	mediate	VERB
admet-942	748	3	production	production	NOUN
admet-942	748	4	of	of	ADP
admet-942	748	5	foams	foam	NOUN
admet-942	748	6	for	for	ADP
admet-942	748	7	biomedical	biomedical	ADJ
admet-942	748	8	applications	application	NOUN
admet-942	748	9	.	.	PUNCT
admet-942	749	1	micromachines	micromachine	NOUN
admet-942	749	2	11	11	NUM
admet-942	749	3	(	(	PUNCT
admet-942	749	4	2020	2020	NUM
admet-942	749	5	)	)	PUNCT
admet-942	749	6	1	1	NUM
admet-942	749	7	-	-	SYM
admet-942	749	8	20	20	NUM
admet-942	749	9	.	.	PUNCT
admet-942	750	1	https://doi.org/10.3390/mi11010083	https://doi.org/10.3390/mi11010083	X
admet-942	750	2	.	.	PUNCT
admet-942	751	1	[	[	X
admet-942	751	2	60	60	NUM
admet-942	751	3	]	]	X
admet-942	751	4	e.s	e.s	PROPN
admet-942	751	5	.	.	PROPN
admet-942	751	6	bishop	bishop	PROPN
admet-942	751	7	,	,	PUNCT
admet-942	751	8	s.	s.	PROPN
admet-942	751	9	mostafa	mostafa	PROPN
admet-942	751	10	,	,	PUNCT
admet-942	751	11	m.	m.	PROPN
admet-942	751	12	pakvasa	pakvasa	PROPN
admet-942	751	13	,	,	PUNCT
admet-942	751	14	h.h	h.h	PROPN
admet-942	751	15	.	.	PROPN
admet-942	751	16	luu	luu	PROPN
admet-942	751	17	,	,	PUNCT
admet-942	751	18	m.j	m.j	PROPN
admet-942	751	19	.	.	PROPN
admet-942	751	20	lee	lee	PROPN
admet-942	751	21	,	,	PUNCT
admet-942	751	22	j.m	j.m	PROPN
admet-942	751	23	.	.	PROPN
admet-942	751	24	wolf	wolf	PROPN
admet-942	751	25	,	,	PUNCT
admet-942	751	26	g.a	g.a	PROPN
admet-942	751	27	.	.	PROPN
admet-942	751	28	ameer	ameer	PROPN
admet-942	751	29	,	,	PUNCT
admet-942	751	30	t.c	t.c	PROPN
admet-942	751	31	.	.	PUNCT
admet-942	752	1	he	he	PRON
admet-942	752	2	,	,	PUNCT
admet-942	752	3	r.r	r.r	PROPN
admet-942	752	4	.	.	PROPN
admet-942	752	5	reid	reid	PROPN
admet-942	752	6	.	.	PUNCT
admet-942	753	1	3	3	NUM
admet-942	753	2	-	-	SYM
admet-942	753	3	d	d	NOUN
admet-942	753	4	bioprinting	bioprinting	NOUN
admet-942	753	5	technologies	technology	NOUN
admet-942	753	6	in	in	ADP
admet-942	753	7	tissue	tissue	NOUN
admet-942	753	8	engineering	engineering	NOUN
admet-942	753	9	and	and	CCONJ
admet-942	753	10	regenerative	regenerative	ADJ
admet-942	753	11	medicine	medicine	NOUN
admet-942	753	12	:	:	PUNCT
admet-942	753	13	current	current	ADJ
admet-942	753	14	and	and	CCONJ
admet-942	753	15	future	future	ADJ
admet-942	753	16	trends	trend	NOUN
admet-942	753	17	.	.	PUNCT
admet-942	754	1	genes	gene	NOUN
admet-942	754	2	and	and	CCONJ
admet-942	754	3	diseases	disease	NOUN
admet-942	754	4	4	4	NUM
admet-942	754	5	(	(	PUNCT
admet-942	754	6	2017	2017	NUM
admet-942	754	7	)	)	PUNCT
admet-942	754	8	185	185	NUM
admet-942	754	9	-	-	SYM
admet-942	754	10	195	195	NUM
admet-942	754	11	.	.	PUNCT
admet-942	754	12	https://doi.org/10.1016/j.gendis.2017.10.002	https://doi.org/10.1016/j.gendis.2017.10.002	PROPN
admet-942	754	13	.	.	PUNCT
admet-942	755	1	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	755	2	https://doi.org/10.1016/j.biomaterials.2019.119367	https://doi.org/10.1016/j.biomaterials.2019.119367	PROPN
admet-942	755	3	https://doi.org/10.1039/c8lc00456k	https://doi.org/10.1039/c8lc00456k	PROPN
admet-942	755	4	https://doi.org/10.3389/fbioe.2018.00197	https://doi.org/10.3389/fbioe.2018.00197	PROPN
admet-942	755	5	https://doi.org/10.1039/c6lc00638h	https://doi.org/10.1039/c6lc00638h	PROPN
admet-942	755	6	https://doi.org/10.3390/mi10030165	https://doi.org/10.3390/mi10030165	PROPN
admet-942	755	7	https://doi.org/10.1016/j.cbi.2018.11.010	https://doi.org/10.1016/j.cbi.2018.11.010	NOUN
admet-942	755	8	https://doi.org/10.1016/j.cell.2016.02.049	https://doi.org/10.1016/j.cell.2016.02.049	PRON
admet-942	755	9	https://doi.org/10.1016/j.trac.2019.05.028	https://doi.org/10.1016/j.trac.2019.05.028	ADJ
admet-942	755	10	https://doi.org/10.1039/c9lc01107b	https://doi.org/10.1039/c9lc01107b	PROPN
admet-942	755	11	https://doi.org/10.1039/c9lc01107b	https://doi.org/10.1039/c9lc01107b	PROPN
admet-942	755	12	https://doi.org/10.1177/1535370217694100	https://doi.org/10.1177/1535370217694100	PROPN
admet-942	755	13	https://doi.org/10.3390/genes9040176	https://doi.org/10.3390/genes9040176	NOUN
admet-942	755	14	https://doi.org/10.1016/j.drudis.2019.03.025	https://doi.org/10.1016/j.drudis.2019.03.025	PROPN
admet-942	755	15	https://doi.org/10.3390/mi11010083	https://doi.org/10.3390/mi11010083	PROPN
admet-942	755	16	https://doi.org/10.1016/j.gendis.2017.10.002	https://doi.org/10.1016/j.gendis.2017.10.002	PROPN
admet-942	755	17	r.	r.	PROPN
admet-942	755	18	vargas	vargas	PROPN
admet-942	755	19	,	,	PUNCT
admet-942	755	20	a.	a.	NOUN
admet-942	755	21	egurbide	egurbide	NOUN
admet-942	755	22	-	-	PUNCT
admet-942	755	23	sifre	sifre	NOUN
admet-942	755	24	and	and	CCONJ
admet-942	755	25	l.	l.	PROPN
admet-942	755	26	medina	medina	PROPN
admet-942	755	27	admet	admet	PROPN
admet-942	755	28	&	&	CCONJ
admet-942	755	29	dmpk	dmpk	PROPN
admet-942	755	30	9(2	9(2	NUM
admet-942	755	31	)	)	PUNCT
admet-942	755	32	(	(	PUNCT
admet-942	755	33	2021	2021	NUM
admet-942	755	34	)	)	PUNCT
admet-942	755	35	111	111	NUM
admet-942	755	36	-	-	SYM
admet-942	755	37	141	141	NUM
admet-942	755	38	136	136	NUM
admet-942	755	39	[	[	X
admet-942	755	40	61	61	NUM
admet-942	755	41	]	]	X
admet-942	755	42	d.	d.	PROPN
admet-942	755	43	huh	huh	PROPN
admet-942	755	44	,	,	PUNCT
admet-942	755	45	b.d	b.d	PROPN
admet-942	755	46	.	.	PROPN
admet-942	755	47	matthews	matthews	PROPN
admet-942	755	48	,	,	PUNCT
admet-942	755	49	a.	a.	NOUN
admet-942	755	50	mammoto	mammoto	PROPN
admet-942	755	51	,	,	PUNCT
admet-942	755	52	m.	m.	NOUN
admet-942	755	53	montoya	montoya	PROPN
admet-942	755	54	-	-	PUNCT
admet-942	755	55	zavala	zavala	PROPN
admet-942	755	56	,	,	PUNCT
admet-942	755	57	h.	h.	PROPN
admet-942	755	58	yuan	yuan	PROPN
admet-942	755	59	hsin	hsin	PROPN
admet-942	755	60	,	,	PUNCT
admet-942	755	61	d.e	d.e	PROPN
admet-942	755	62	.	.	PROPN
admet-942	755	63	ingber	ingber	PROPN
admet-942	755	64	.	.	PUNCT
admet-942	756	1	reconstituting	reconstitute	VERB
admet-942	756	2	organ	organ	NOUN
admet-942	756	3	-	-	PUNCT
admet-942	756	4	level	level	NOUN
admet-942	756	5	lung	lung	NOUN
admet-942	756	6	functions	function	NOUN
admet-942	756	7	on	on	ADP
admet-942	756	8	a	a	DET
admet-942	756	9	chip	chip	NOUN
admet-942	756	10	.	.	PUNCT
admet-942	757	1	science	science	NOUN
admet-942	757	2	.	.	PUNCT
admet-942	758	1	328	328	NUM
admet-942	758	2	(	(	PUNCT
admet-942	758	3	2010	2010	NUM
admet-942	758	4	)	)	PUNCT
admet-942	758	5	1662	1662	NUM
admet-942	758	6	-	-	SYM
admet-942	758	7	1668	1668	NUM
admet-942	758	8	.	.	PUNCT
admet-942	759	1	https://doi.org/10.1126/science.1188302	https://doi.org/10.1126/science.1188302	ADJ
admet-942	759	2	.	.	PUNCT
admet-942	760	1	[	[	X
admet-942	760	2	62	62	NUM
admet-942	760	3	]	]	PUNCT
admet-942	760	4	t.	t.	NOUN
admet-942	760	5	takebe	takebe	NOUN
admet-942	760	6	,	,	PUNCT
admet-942	760	7	b.	b.	PROPN
admet-942	760	8	zhang	zhang	PROPN
admet-942	760	9	,	,	PUNCT
admet-942	760	10	m.	m.	NOUN
admet-942	760	11	radisic	radisic	NOUN
admet-942	760	12	.	.	PUNCT
admet-942	761	1	synergistic	synergistic	ADJ
admet-942	761	2	engineering	engineering	NOUN
admet-942	761	3	:	:	PUNCT
admet-942	761	4	organoids	organoid	NOUN
admet-942	761	5	meet	meet	VERB
admet-942	761	6	organs	organ	NOUN
admet-942	761	7	-	-	PUNCT
admet-942	761	8	on	on	ADP
admet-942	761	9	-	-	PUNCT
admet-942	761	10	a	a	DET
admet-942	761	11	-	-	PUNCT
admet-942	761	12	chip	chip	NOUN
admet-942	761	13	.	.	PUNCT
admet-942	762	1	cell	cell	NOUN
admet-942	762	2	stem	stem	NOUN
admet-942	762	3	cell	cell	NOUN
admet-942	762	4	21	21	NUM
admet-942	762	5	(	(	PUNCT
admet-942	762	6	2017	2017	NUM
admet-942	762	7	)	)	PUNCT
admet-942	762	8	297	297	NUM
admet-942	762	9	-	-	SYM
admet-942	762	10	300	300	NUM
admet-942	762	11	.	.	PUNCT
admet-942	763	1	https://doi.org/10.1016/j.stem.2017.08.016	https://doi.org/10.1016/j.stem.2017.08.016	NUM
admet-942	763	2	.	.	PUNCT
admet-942	764	1	[	[	X
admet-942	764	2	63	63	NUM
admet-942	764	3	]	]	PUNCT
admet-942	764	4	p.	p.	NOUN
admet-942	765	1	saglam	saglam	PROPN
admet-942	765	2	-	-	NOUN
admet-942	765	3	metiner	metiner	NOUN
admet-942	765	4	,	,	PUNCT
admet-942	765	5	s.	s.	PROPN
admet-942	765	6	gulce	gulce	PROPN
admet-942	765	7	-	-	PUNCT
admet-942	765	8	iz	iz	PROPN
admet-942	765	9	,	,	PUNCT
admet-942	765	10	c.	c.	PROPN
admet-942	765	11	biray	biray	PROPN
admet-942	765	12	-	-	PUNCT
admet-942	765	13	avci	avci	PROPN
admet-942	765	14	.	.	PUNCT
admet-942	766	1	bioengineering	bioengineere	VERB
admet-942	766	2	-	-	PUNCT
admet-942	766	3	inspired	inspire	VERB
admet-942	766	4	three	three	NUM
admet-942	766	5	-	-	PUNCT
admet-942	766	6	dimensional	dimensional	ADJ
admet-942	766	7	culture	culture	NOUN
admet-942	766	8	systems	system	NOUN
admet-942	766	9	:	:	PUNCT
admet-942	766	10	organoids	organoid	NOUN
admet-942	766	11	to	to	PART
admet-942	766	12	create	create	VERB
admet-942	766	13	tumor	tumor	NOUN
admet-942	766	14	microenvironment	microenvironment	NOUN
admet-942	766	15	.	.	PUNCT
admet-942	767	1	gene	gene	NOUN
admet-942	767	2	686	686	NUM
admet-942	767	3	(	(	PUNCT
admet-942	767	4	2019	2019	NUM
admet-942	767	5	)	)	PUNCT
admet-942	767	6	203	203	NUM
admet-942	767	7	-	-	SYM
admet-942	767	8	212	212	NUM
admet-942	767	9	.	.	PUNCT
admet-942	768	1	https://doi.org/10.1016/j.gene.2018.11.058	https://doi.org/10.1016/j.gene.2018.11.058	NOUN
admet-942	768	2	.	.	PUNCT
admet-942	769	1	[	[	X
admet-942	769	2	64	64	NUM
admet-942	769	3	]	]	PUNCT
admet-942	769	4	j.-p	j.-p	PROPN
admet-942	769	5	.	.	PUNCT
admet-942	769	6	frimat	frimat	PROPN
admet-942	769	7	,	,	PUNCT
admet-942	769	8	r.	r.	PROPN
admet-942	769	9	luttge	luttge	PROPN
admet-942	769	10	.	.	PUNCT
admet-942	770	1	the	the	DET
admet-942	770	2	need	need	NOUN
admet-942	770	3	for	for	ADP
admet-942	770	4	physiological	physiological	ADJ
admet-942	770	5	micro	micro	ADJ
admet-942	770	6	-	-	ADJ
admet-942	770	7	nanofluidic	nanofluidic	ADJ
admet-942	770	8	systems	system	NOUN
admet-942	770	9	of	of	ADP
admet-942	770	10	the	the	DET
admet-942	770	11	brain	brain	NOUN
admet-942	770	12	.	.	PUNCT
admet-942	771	1	frontiers	frontier	NOUN
admet-942	771	2	in	in	ADP
admet-942	771	3	bioengineering	bioengineering	NOUN
admet-942	771	4	and	and	CCONJ
admet-942	771	5	biotechnology	biotechnology	NOUN
admet-942	771	6	7	7	NUM
admet-942	771	7	(	(	PUNCT
admet-942	771	8	2019	2019	NUM
admet-942	771	9	)	)	PUNCT
admet-942	771	10	1	1	NUM
admet-942	771	11	-	-	SYM
admet-942	771	12	11	11	NUM
admet-942	771	13	.	.	PUNCT
admet-942	772	1	https://doi.org/10.3389/fbioe.2019.00100	https://doi.org/10.3389/fbioe.2019.00100	PROPN
admet-942	772	2	.	.	PUNCT
admet-942	773	1	[	[	X
admet-942	773	2	65	65	NUM
admet-942	773	3	]	]	X
admet-942	773	4	m.l	m.l	PROPN
admet-942	773	5	.	.	PROPN
admet-942	773	6	alec	alec	PROPN
admet-942	773	7	smith	smith	PROPN
admet-942	773	8	,	,	PUNCT
admet-942	773	9	jesse	jesse	PROPN
admet-942	773	10	macadangdang	macadangdang	PROPN
admet-942	773	11	,	,	PUNCT
admet-942	773	12	winnie	winnie	PROPN
admet-942	773	13	leung	leung	PROPN
admet-942	773	14	,	,	PUNCT
admet-942	773	15	d.-h	d.-h	PROPN
admet-942	773	16	.	.	PUNCT
admet-942	774	1	kim	kim	PROPN
admet-942	774	2	.	.	PUNCT
admet-942	775	1	human	human	PROPN
admet-942	775	2	ipsc	ipsc	PROPN
admet-942	775	3	-	-	PUNCT
admet-942	775	4	derived	derive	VERB
admet-942	775	5	cardiomyocytes	cardiomyocyte	NOUN
admet-942	775	6	and	and	CCONJ
admet-942	775	7	tissue	tissue	NOUN
admet-942	775	8	engineering	engineering	NOUN
admet-942	775	9	strategies	strategy	NOUN
admet-942	775	10	for	for	ADP
admet-942	775	11	disease	disease	NOUN
admet-942	775	12	modeling	modeling	NOUN
admet-942	775	13	and	and	CCONJ
admet-942	775	14	drug	drug	NOUN
admet-942	775	15	screening	screening	NOUN
admet-942	775	16	.	.	PUNCT
admet-942	776	1	biotechnol	biotechnol	PROPN
admet-942	776	2	adv	adv	PROPN
admet-942	776	3	.	.	PROPN
admet-942	777	1	176	176	NUM
admet-942	777	2	(	(	PUNCT
admet-942	777	3	2017	2017	NUM
admet-942	777	4	)	)	PUNCT
admet-942	777	5	139	139	NUM
admet-942	777	6	-	-	SYM
admet-942	777	7	148	148	NUM
admet-942	777	8	.	.	PUNCT
admet-942	778	1	https://doi.org/10.1016/j.biotechadv.2016.12.002	https://doi.org/10.1016/j.biotechadv.2016.12.002	NOUN
admet-942	778	2	.	.	PUNCT
admet-942	779	1	[	[	X
admet-942	779	2	66	66	NUM
admet-942	779	3	]	]	PUNCT
admet-942	779	4	a.	a.	NOUN
admet-942	779	5	skardal	skardal	NOUN
admet-942	779	6	,	,	PUNCT
admet-942	779	7	s.	s.	PROPN
admet-942	779	8	v.	v.	PROPN
admet-942	779	9	murphy	murphy	PROPN
admet-942	779	10	,	,	PUNCT
admet-942	779	11	m.	m.	NOUN
admet-942	779	12	devarasetty	devarasetty	PROPN
admet-942	779	13	,	,	PUNCT
admet-942	779	14	i.	i.	PROPN
admet-942	779	15	mead	mead	PROPN
admet-942	779	16	,	,	PUNCT
admet-942	779	17	h.w	h.w	PROPN
admet-942	779	18	.	.	PROPN
admet-942	779	19	kang	kang	PROPN
admet-942	779	20	,	,	PUNCT
admet-942	779	21	y.j	y.j	PROPN
admet-942	779	22	.	.	PUNCT
admet-942	779	23	seol	seol	PROPN
admet-942	779	24	,	,	PUNCT
admet-942	779	25	y.s	y.s	PROPN
admet-942	779	26	.	.	PROPN
admet-942	779	27	zhang	zhang	PROPN
admet-942	779	28	,	,	PUNCT
admet-942	779	29	s.r	s.r	PROPN
admet-942	779	30	.	.	PROPN
admet-942	779	31	shin	shin	PROPN
admet-942	779	32	,	,	PUNCT
admet-942	779	33	l.	l.	PROPN
admet-942	779	34	zhao	zhao	PROPN
admet-942	779	35	,	,	PUNCT
admet-942	779	36	j.	j.	PROPN
admet-942	779	37	aleman	aleman	PROPN
admet-942	779	38	,	,	PUNCT
admet-942	779	39	a.r	a.r	PROPN
admet-942	779	40	.	.	PROPN
admet-942	779	41	hall	hall	PROPN
admet-942	779	42	,	,	PUNCT
admet-942	779	43	t.d	t.d	PROPN
admet-942	779	44	.	.	PROPN
admet-942	779	45	shupe	shupe	PROPN
admet-942	779	46	,	,	PUNCT
admet-942	779	47	a.	a.	PROPN
admet-942	779	48	kleensang	kleensang	PROPN
admet-942	779	49	,	,	PUNCT
admet-942	779	50	m.r	m.r	PROPN
admet-942	779	51	.	.	PROPN
admet-942	779	52	dokmeci	dokmeci	PROPN
admet-942	779	53	,	,	PUNCT
admet-942	779	54	s.	s.	PROPN
admet-942	779	55	jin	jin	PROPN
admet-942	779	56	lee	lee	PROPN
admet-942	779	57	,	,	PUNCT
admet-942	779	58	j.d	j.d	PROPN
admet-942	779	59	.	.	PROPN
admet-942	779	60	jackson	jackson	PROPN
admet-942	779	61	,	,	PUNCT
admet-942	779	62	j.j	j.j	PROPN
admet-942	779	63	.	.	PROPN
admet-942	779	64	yoo	yoo	PROPN
admet-942	779	65	,	,	PUNCT
admet-942	779	66	t.	t.	PROPN
admet-942	779	67	hartung	hartung	PROPN
admet-942	779	68	,	,	PUNCT
admet-942	779	69	a.	a.	NOUN
admet-942	779	70	khademhosseini	khademhosseini	PROPN
admet-942	779	71	,	,	PUNCT
admet-942	779	72	s.	s.	PROPN
admet-942	779	73	soker	soker	PROPN
admet-942	779	74	,	,	PUNCT
admet-942	779	75	c.e	c.e	PROPN
admet-942	779	76	.	.	PROPN
admet-942	779	77	bishop	bishop	PROPN
admet-942	779	78	,	,	PUNCT
admet-942	779	79	a.	a.	PROPN
admet-942	779	80	atala	atala	PROPN
admet-942	779	81	.	.	PUNCT
admet-942	780	1	multi	multi	ADJ
admet-942	780	2	-	-	ADJ
admet-942	780	3	tissue	tissue	ADJ
admet-942	780	4	interactions	interaction	NOUN
admet-942	780	5	in	in	ADP
admet-942	780	6	an	an	DET
admet-942	780	7	integrated	integrate	VERB
admet-942	780	8	three	three	NUM
admet-942	780	9	-	-	PUNCT
admet-942	780	10	tissue	tissue	NOUN
admet-942	780	11	organ	organ	NOUN
admet-942	780	12	-	-	PUNCT
admet-942	780	13	on	on	ADP
admet-942	780	14	-	-	PUNCT
admet-942	780	15	a	a	DET
admet-942	780	16	-	-	PUNCT
admet-942	780	17	chip	chip	NOUN
admet-942	780	18	platform	platform	NOUN
admet-942	780	19	.	.	PUNCT
admet-942	781	1	scientific	scientific	ADJ
admet-942	781	2	reports	report	NOUN
admet-942	781	3	7	7	NUM
admet-942	781	4	(	(	PUNCT
admet-942	781	5	2017	2017	NUM
admet-942	781	6	)	)	PUNCT
admet-942	781	7	1	1	NUM
admet-942	781	8	-	-	SYM
admet-942	781	9	16	16	NUM
admet-942	781	10	.	.	PUNCT
admet-942	782	1	https://doi.org/10.1038/s41598-017-08879-x	https://doi.org/10.1038/s41598-017-08879-x	NOUN
admet-942	782	2	.	.	PUNCT
admet-942	783	1	[	[	X
admet-942	783	2	67	67	NUM
admet-942	783	3	]	]	X
admet-942	783	4	c.p	c.p	PROPN
admet-942	783	5	.	.	PROPN
admet-942	783	6	pires	pires	PROPN
admet-942	783	7	de	de	PROPN
admet-942	783	8	mello	mello	PROPN
admet-942	783	9	,	,	PUNCT
admet-942	783	10	c.	c.	PROPN
admet-942	783	11	carmona	carmona	PROPN
admet-942	783	12	-	-	PUNCT
admet-942	783	13	moran	moran	PROPN
admet-942	783	14	,	,	PUNCT
admet-942	783	15	c.w	c.w	PROPN
admet-942	783	16	.	.	PROPN
admet-942	783	17	mcaleer	mcaleer	PROPN
admet-942	783	18	,	,	PUNCT
admet-942	783	19	j.	j.	PROPN
admet-942	783	20	perez	perez	PROPN
admet-942	783	21	,	,	PUNCT
admet-942	783	22	e.a	e.a	PROPN
admet-942	783	23	.	.	PROPN
admet-942	783	24	coln	coln	PROPN
admet-942	783	25	,	,	PUNCT
admet-942	783	26	c.j	c.j	PROPN
admet-942	783	27	.	.	PROPN
admet-942	783	28	long	long	PROPN
admet-942	783	29	,	,	PUNCT
admet-942	783	30	c.	c.	PROPN
admet-942	783	31	oleaga	oleaga	PROPN
admet-942	783	32	,	,	PUNCT
admet-942	783	33	a.	a.	PROPN
admet-942	783	34	riu	riu	PROPN
admet-942	783	35	,	,	PUNCT
admet-942	783	36	r.	r.	PROPN
admet-942	783	37	note	note	PROPN
admet-942	783	38	,	,	PUNCT
admet-942	783	39	s.	s.	PROPN
admet-942	783	40	teissier	teissier	PROPN
admet-942	783	41	,	,	PUNCT
admet-942	783	42	j.	j.	PROPN
admet-942	783	43	langer	langer	PROPN
admet-942	783	44	,	,	PUNCT
admet-942	783	45	j.j	j.j	PROPN
admet-942	783	46	.	.	PROPN
admet-942	783	47	hickman	hickman	PROPN
admet-942	783	48	.	.	PUNCT
admet-942	784	1	microphysiological	microphysiological	ADJ
admet-942	784	2	heart	heart	NOUN
admet-942	784	3	-	-	PUNCT
admet-942	784	4	liver	liver	NOUN
admet-942	784	5	body	body	NOUN
admet-942	784	6	-	-	PUNCT
admet-942	784	7	on	on	ADP
admet-942	784	8	-	-	PUNCT
admet-942	784	9	a	a	DET
admet-942	784	10	-	-	PUNCT
admet-942	784	11	chip	chip	NOUN
admet-942	784	12	system	system	NOUN
admet-942	784	13	with	with	ADP
admet-942	784	14	a	a	DET
admet-942	784	15	skin	skin	NOUN
admet-942	784	16	mimic	mimic	NOUN
admet-942	784	17	for	for	ADP
admet-942	784	18	evaluating	evaluate	VERB
admet-942	784	19	topical	topical	ADJ
admet-942	784	20	drug	drug	NOUN
admet-942	784	21	delivery	delivery	NOUN
admet-942	784	22	.	.	PUNCT
admet-942	785	1	lab	lab	NOUN
admet-942	785	2	on	on	ADP
admet-942	785	3	a	a	DET
admet-942	785	4	chip	chip	NOUN
admet-942	785	5	20	20	NUM
admet-942	785	6	(	(	PUNCT
admet-942	785	7	2020	2020	NUM
admet-942	785	8	)	)	PUNCT
admet-942	785	9	749	749	NUM
admet-942	785	10	-	-	SYM
admet-942	785	11	759	759	NUM
admet-942	785	12	.	.	PUNCT
admet-942	786	1	https://doi.org/10.1039/c9lc00861f	https://doi.org/10.1039/c9lc00861f	X
admet-942	786	2	.	.	PUNCT
admet-942	787	1	[	[	X
admet-942	787	2	68	68	NUM
admet-942	787	3	]	]	X
admet-942	787	4	m.b	m.b	PROPN
admet-942	787	5	.	.	PROPN
admet-942	787	6	esch	esch	PROPN
admet-942	787	7	,	,	PUNCT
admet-942	787	8	g.j	g.j	PROPN
admet-942	787	9	.	.	PROPN
admet-942	787	10	mahler	mahler	PROPN
admet-942	787	11	,	,	PUNCT
admet-942	787	12	t.	t.	PROPN
admet-942	787	13	stokol	stokol	PROPN
admet-942	787	14	,	,	PUNCT
admet-942	787	15	m.l	m.l	PROPN
admet-942	787	16	.	.	PROPN
admet-942	787	17	shuler	shuler	PROPN
admet-942	787	18	.	.	PUNCT
admet-942	787	19	body	body	NOUN
admet-942	787	20	-	-	PUNCT
admet-942	787	21	on	on	ADP
admet-942	787	22	-	-	PUNCT
admet-942	787	23	a	a	DET
admet-942	787	24	-	-	PUNCT
admet-942	787	25	chip	chip	NOUN
admet-942	787	26	simulation	simulation	NOUN
admet-942	787	27	with	with	ADP
admet-942	787	28	gastrointestinal	gastrointestinal	ADJ
admet-942	787	29	tract	tract	NOUN
admet-942	787	30	and	and	CCONJ
admet-942	787	31	liver	liver	NOUN
admet-942	787	32	tissues	tissue	NOUN
admet-942	787	33	suggests	suggest	VERB
admet-942	787	34	that	that	SCONJ
admet-942	787	35	ingested	ingest	VERB
admet-942	787	36	nanoparticles	nanoparticle	NOUN
admet-942	787	37	have	have	VERB
admet-942	787	38	the	the	DET
admet-942	787	39	potential	potential	NOUN
admet-942	787	40	to	to	PART
admet-942	787	41	cause	cause	VERB
admet-942	787	42	liver	liver	NOUN
admet-942	787	43	injury	injury	NOUN
admet-942	787	44	.	.	PUNCT
admet-942	788	1	lab	lab	NOUN
admet-942	788	2	on	on	ADP
admet-942	788	3	a	a	DET
admet-942	788	4	chip	chip	NOUN
admet-942	788	5	14	14	NUM
admet-942	788	6	(	(	PUNCT
admet-942	788	7	2014	2014	NUM
admet-942	788	8	)	)	PUNCT
admet-942	788	9	3081	3081	NUM
admet-942	788	10	-	-	SYM
admet-942	788	11	3092	3092	NUM
admet-942	788	12	.	.	PUNCT
admet-942	789	1	https://doi.org/10.1039/c4lc00371c	https://doi.org/10.1039/c4lc00371c	NOUN
admet-942	789	2	.	.	PUNCT
admet-942	790	1	[	[	X
admet-942	790	2	69	69	NUM
admet-942	790	3	]	]	PUNCT
admet-942	790	4	p.	p.	PROPN
admet-942	790	5	de	de	PROPN
admet-942	790	6	haan	haan	PROPN
admet-942	790	7	,	,	PUNCT
admet-942	790	8	m.a	m.a	PROPN
admet-942	790	9	.	.	PROPN
admet-942	790	10	ianovska	ianovska	PROPN
admet-942	790	11	,	,	PUNCT
admet-942	790	12	k.	k.	PROPN
admet-942	790	13	mathwig	mathwig	PROPN
admet-942	790	14	,	,	PUNCT
admet-942	790	15	g.a.a	g.a.a	PROPN
admet-942	790	16	.	.	PUNCT
admet-942	791	1	van	van	PROPN
admet-942	791	2	lieshout	lieshout	PROPN
admet-942	791	3	,	,	PUNCT
admet-942	791	4	v.	v.	PROPN
admet-942	791	5	triantis	triantis	PROPN
admet-942	791	6	,	,	PUNCT
admet-942	791	7	h.	h.	PROPN
admet-942	791	8	bouwmeester	bouwmeester	PROPN
admet-942	791	9	,	,	PUNCT
admet-942	791	10	e.	e.	PROPN
admet-942	791	11	verpoorte	verpoorte	PROPN
admet-942	791	12	.	.	PUNCT
admet-942	792	1	digestion	digestion	NOUN
admet-942	792	2	-	-	PUNCT
admet-942	792	3	on	on	ADP
admet-942	792	4	-	-	PUNCT
admet-942	792	5	a	a	DET
admet-942	792	6	-	-	PUNCT
admet-942	792	7	chip	chip	NOUN
admet-942	792	8	:	:	PUNCT
admet-942	792	9	a	a	DET
admet-942	792	10	continuous	continuous	ADJ
admet-942	792	11	-	-	PUNCT
admet-942	792	12	flow	flow	NOUN
admet-942	792	13	modular	modular	ADJ
admet-942	792	14	microsystem	microsystem	NOUN
admet-942	792	15	recreating	recreate	VERB
admet-942	792	16	enzymatic	enzymatic	ADJ
admet-942	792	17	digestion	digestion	NOUN
admet-942	792	18	in	in	ADP
admet-942	792	19	the	the	DET
admet-942	792	20	gastrointestinal	gastrointestinal	ADJ
admet-942	792	21	tract	tract	NOUN
admet-942	792	22	.	.	PUNCT
admet-942	793	1	lab	lab	NOUN
admet-942	793	2	on	on	ADP
admet-942	793	3	a	a	DET
admet-942	793	4	chip	chip	NOUN
admet-942	793	5	19	19	NUM
admet-942	793	6	(	(	PUNCT
admet-942	793	7	2019	2019	NUM
admet-942	793	8	)	)	PUNCT
admet-942	793	9	1599	1599	NUM
admet-942	793	10	-	-	SYM
admet-942	793	11	1609	1609	NUM
admet-942	793	12	.	.	PUNCT
admet-942	794	1	https://doi.org/10.1039/c8lc01080c	https://doi.org/10.1039/c8lc01080c	NOUN
admet-942	794	2	.	.	PUNCT
admet-942	795	1	[	[	X
admet-942	795	2	70	70	NUM
admet-942	795	3	]	]	X
admet-942	795	4	h.	h.	PROPN
admet-942	795	5	chen	chen	PROPN
admet-942	795	6	,	,	PUNCT
admet-942	795	7	z.	z.	PROPN
admet-942	795	8	yu	yu	PROPN
admet-942	795	9	,	,	PUNCT
admet-942	795	10	s.	s.	PROPN
admet-942	795	11	bai	bai	PROPN
admet-942	795	12	,	,	PUNCT
admet-942	795	13	h.	h.	PROPN
admet-942	795	14	lu	lu	PROPN
admet-942	795	15	,	,	PUNCT
admet-942	795	16	d.	d.	PROPN
admet-942	795	17	xu	xu	PROPN
admet-942	795	18	,	,	PUNCT
admet-942	795	19	c.	c.	PROPN
admet-942	795	20	chen	chen	PROPN
admet-942	795	21	,	,	PUNCT
admet-942	795	22	d.	d.	PROPN
admet-942	795	23	liu	liu	PROPN
admet-942	795	24	,	,	PUNCT
admet-942	795	25	y.	y.	PROPN
admet-942	795	26	zhu	zhu	PROPN
admet-942	795	27	.	.	PUNCT
admet-942	796	1	microfluidic	microfluidic	ADJ
admet-942	796	2	models	model	NOUN
admet-942	796	3	of	of	ADP
admet-942	796	4	physiological	physiological	ADJ
admet-942	796	5	or	or	CCONJ
admet-942	796	6	pathological	pathological	ADJ
admet-942	796	7	flow	flow	NOUN
admet-942	796	8	shear	shear	NOUN
admet-942	796	9	stress	stress	NOUN
admet-942	796	10	for	for	ADP
admet-942	796	11	cell	cell	NOUN
admet-942	796	12	biology	biology	NOUN
admet-942	796	13	,	,	PUNCT
admet-942	796	14	disease	disease	NOUN
admet-942	796	15	modeling	modeling	NOUN
admet-942	796	16	and	and	CCONJ
admet-942	796	17	drug	drug	NOUN
admet-942	796	18	development	development	NOUN
admet-942	796	19	.	.	PUNCT
admet-942	797	1	trends	trend	NOUN
admet-942	797	2	in	in	ADP
admet-942	797	3	analytical	analytical	ADJ
admet-942	797	4	chemistry	chemistry	NOUN
admet-942	797	5	117	117	NUM
admet-942	797	6	(	(	PUNCT
admet-942	797	7	2019	2019	NUM
admet-942	797	8	)	)	PUNCT
admet-942	797	9	186	186	NUM
admet-942	797	10	-	-	SYM
admet-942	797	11	199	199	NUM
admet-942	797	12	.	.	PUNCT
admet-942	798	1	https://doi.org/10.1016/j.trac.2019.06.023	https://doi.org/10.1016/j.trac.2019.06.023	NOUN
admet-942	798	2	.	.	PUNCT
admet-942	799	1	[	[	X
admet-942	799	2	71	71	NUM
admet-942	799	3	]	]	X
admet-942	799	4	d.	d.	PROPN
admet-942	799	5	kim	kim	PROPN
admet-942	799	6	,	,	PUNCT
admet-942	799	7	x.	x.	PROPN
admet-942	799	8	wu	wu	PROPN
admet-942	799	9	,	,	PUNCT
admet-942	799	10	a.t	a.t	PROPN
admet-942	799	11	.	.	PROPN
admet-942	799	12	young	young	PROPN
admet-942	799	13	,	,	PUNCT
admet-942	799	14	c.l	c.l	PROPN
admet-942	799	15	.	.	PROPN
admet-942	799	16	haynes	haynes	PROPN
admet-942	799	17	.	.	PUNCT
admet-942	800	1	microfluidics	microfluidic	NOUN
admet-942	800	2	-	-	PUNCT
admet-942	800	3	based	base	VERB
admet-942	800	4	in	in	ADP
admet-942	800	5	vivo	vivo	ADJ
admet-942	800	6	mimetic	mimetic	ADJ
admet-942	800	7	systems	system	NOUN
admet-942	800	8	for	for	ADP
admet-942	800	9	the	the	DET
admet-942	800	10	study	study	NOUN
admet-942	800	11	of	of	ADP
admet-942	800	12	cellular	cellular	ADJ
admet-942	800	13	biology	biology	NOUN
admet-942	800	14	.	.	PUNCT
admet-942	801	1	accounts	account	NOUN
admet-942	801	2	of	of	ADP
admet-942	801	3	chemical	chemical	ADJ
admet-942	801	4	research	research	NOUN
admet-942	801	5	47	47	NUM
admet-942	801	6	(	(	PUNCT
admet-942	801	7	2014	2014	NUM
admet-942	801	8	)	)	PUNCT
admet-942	801	9	1165	1165	NUM
admet-942	801	10	-	-	SYM
admet-942	801	11	1173	1173	NUM
admet-942	801	12	.	.	PUNCT
admet-942	802	1	https://doi.org/10.1021/ar4002608	https://doi.org/10.1021/ar4002608	X
admet-942	802	2	.	.	PUNCT
admet-942	803	1	[	[	X
admet-942	803	2	72	72	NUM
admet-942	803	3	]	]	X
admet-942	803	4	a.	a.	NOUN
admet-942	803	5	sontheimer	sontheimer	PROPN
admet-942	803	6	-	-	PUNCT
admet-942	803	7	phelps	phelps	PROPN
admet-942	803	8	,	,	PUNCT
admet-942	803	9	d.b	d.b	PROPN
admet-942	803	10	.	.	PROPN
admet-942	803	11	chou	chou	PROPN
admet-942	803	12	,	,	PUNCT
admet-942	803	13	a.	a.	PROPN
admet-942	803	14	tovaglieri	tovaglieri	PROPN
admet-942	803	15	,	,	PUNCT
admet-942	803	16	t.c	t.c	PROPN
admet-942	803	17	.	.	PROPN
admet-942	803	18	ferrante	ferrante	PROPN
admet-942	803	19	,	,	PUNCT
admet-942	803	20	t.	t.	NOUN
admet-942	803	21	duckworth	duckworth	PROPN
admet-942	803	22	,	,	PUNCT
admet-942	803	23	c.	c.	PROPN
admet-942	803	24	fadel	fadel	PROPN
admet-942	803	25	,	,	PUNCT
admet-942	803	26	v.	v.	PROPN
admet-942	803	27	frismantas	frismantas	PROPN
admet-942	803	28	,	,	PUNCT
admet-942	803	29	a.d	a.d	PROPN
admet-942	803	30	.	.	PROPN
admet-942	803	31	sutherland	sutherland	PROPN
admet-942	803	32	,	,	PUNCT
admet-942	803	33	s.	s.	PROPN
admet-942	803	34	jalili	jalili	PROPN
admet-942	803	35	-	-	PUNCT
admet-942	803	36	firoozinezhad	firoozinezhad	VERB
admet-942	803	37	,	,	PUNCT
admet-942	803	38	m.	m.	NOUN
admet-942	803	39	kasendra	kasendra	PROPN
admet-942	803	40	,	,	PUNCT
admet-942	803	41	e.	e.	PROPN
admet-942	803	42	stas	stas	PROPN
admet-942	803	43	,	,	PUNCT
admet-942	803	44	j.c	j.c	PROPN
admet-942	803	45	.	.	PROPN
admet-942	803	46	weaver	weaver	PROPN
admet-942	803	47	,	,	PUNCT
admet-942	803	48	c.a	c.a	PROPN
admet-942	803	49	.	.	PROPN
admet-942	803	50	richmond	richmond	PROPN
admet-942	803	51	,	,	PUNCT
admet-942	803	52	o.	o.	PROPN
admet-942	803	53	levy	levy	PROPN
admet-942	803	54	,	,	PUNCT
admet-942	803	55	r.	r.	PROPN
admet-942	803	56	prantil	prantil	PROPN
admet-942	803	57	-	-	PUNCT
admet-942	803	58	baun	baun	NOUN
admet-942	803	59	,	,	PUNCT
admet-942	803	60	d.t	d.t	PROPN
admet-942	803	61	.	.	PROPN
admet-942	803	62	breault	breault	PROPN
admet-942	803	63	,	,	PUNCT
admet-942	803	64	d.e	d.e	PROPN
admet-942	803	65	.	.	PROPN
admet-942	803	66	ingber	ingber	PROPN
admet-942	803	67	.	.	PUNCT
admet-942	804	1	human	human	ADJ
admet-942	804	2	colon	colon	NOUN
admet-942	804	3	-	-	PUNCT
admet-942	804	4	on	on	ADP
admet-942	804	5	-	-	PUNCT
admet-942	804	6	a	a	DET
admet-942	804	7	-	-	PUNCT
admet-942	804	8	chip	chip	NOUN
admet-942	804	9	enables	enable	VERB
admet-942	804	10	continuous	continuous	ADJ
admet-942	804	11	in	in	ADP
admet-942	804	12	vitro	vitro	X
admet-942	804	13	analysis	analysis	NOUN
admet-942	804	14	of	of	ADP
admet-942	804	15	colon	colon	NOUN
admet-942	804	16	mucus	mucus	NOUN
admet-942	804	17	layer	layer	NOUN
admet-942	804	18	accumulation	accumulation	NOUN
admet-942	804	19	and	and	CCONJ
admet-942	804	20	physiology	physiology	NOUN
admet-942	804	21	.	.	PUNCT
admet-942	805	1	cmgh	cmgh	NOUN
admet-942	805	2	9	9	NUM
admet-942	805	3	(	(	PUNCT
admet-942	805	4	2020	2020	NUM
admet-942	805	5	)	)	PUNCT
admet-942	805	6	507	507	NUM
admet-942	805	7	-	-	SYM
admet-942	805	8	526	526	NUM
admet-942	805	9	.	.	PUNCT
admet-942	806	1	https://doi.org/10.1016/j.jcmgh.2019.11.008	https://doi.org/10.1016/j.jcmgh.2019.11.008	NOUN
admet-942	806	2	.	.	PUNCT
admet-942	807	1	[	[	X
admet-942	807	2	73	73	NUM
admet-942	807	3	]	]	PUNCT
admet-942	807	4	s.	s.	PROPN
admet-942	807	5	mi	mi	PROPN
admet-942	807	6	,	,	PUNCT
admet-942	807	7	h.	h.	PROPN
admet-942	807	8	pu	pu	PROPN
admet-942	807	9	,	,	PUNCT
admet-942	807	10	s.	s.	PROPN
admet-942	807	11	xia	xia	PROPN
admet-942	807	12	,	,	PUNCT
admet-942	807	13	w.	w.	PROPN
admet-942	807	14	sun	sun	PROPN
admet-942	807	15	.	.	PUNCT
admet-942	808	1	a	a	DET
admet-942	808	2	minimized	minimized	ADJ
admet-942	808	3	valveless	valveless	NOUN
admet-942	808	4	electromagnetic	electromagnetic	NOUN
admet-942	808	5	micropump	micropump	NOUN
admet-942	808	6	for	for	ADP
admet-942	808	7	microfluidic	microfluidic	ADJ
admet-942	808	8	actuation	actuation	NOUN
admet-942	808	9	on	on	ADP
admet-942	808	10	organ	organ	NOUN
admet-942	808	11	chips	chip	NOUN
admet-942	808	12	.	.	PUNCT
admet-942	809	1	sensors	sensor	NOUN
admet-942	809	2	and	and	CCONJ
admet-942	809	3	actuators	actuator	NOUN
admet-942	809	4	,	,	PUNCT
admet-942	809	5	a	a	PRON
admet-942	809	6	:	:	PUNCT
admet-942	809	7	physical	physical	ADJ
admet-942	809	8	301	301	NUM
admet-942	809	9	(	(	PUNCT
admet-942	809	10	2020	2020	NUM
admet-942	809	11	)	)	PUNCT
admet-942	809	12	111704	111704	NUM
admet-942	809	13	.	.	PUNCT
admet-942	810	1	https://doi.org/10.1016/j.sna.2019.111704	https://doi.org/10.1016/j.sna.2019.111704	VERB
admet-942	810	2	.	.	PUNCT
admet-942	811	1	[	[	X
admet-942	811	2	74	74	NUM
admet-942	811	3	]	]	X
admet-942	811	4	g.d	g.d	PROPN
admet-942	811	5	.	.	PROPN
admet-942	811	6	vatine	vatine	PROPN
admet-942	811	7	,	,	PUNCT
admet-942	811	8	r.	r.	PROPN
admet-942	811	9	barrile	barrile	PROPN
admet-942	811	10	,	,	PUNCT
admet-942	811	11	m.j	m.j	PROPN
admet-942	811	12	.	.	PROPN
admet-942	811	13	workman	workman	PROPN
admet-942	811	14	,	,	PUNCT
admet-942	811	15	s.	s.	PROPN
admet-942	811	16	sances	sances	PROPN
admet-942	811	17	,	,	PUNCT
admet-942	811	18	b.k	b.k	PROPN
admet-942	811	19	.	.	PUNCT
admet-942	811	20	barriga	barriga	PROPN
admet-942	811	21	,	,	PUNCT
admet-942	811	22	m.	m.	NOUN
admet-942	811	23	rahnama	rahnama	PROPN
admet-942	811	24	,	,	PUNCT
admet-942	811	25	s.	s.	PROPN
admet-942	811	26	barthakur	barthakur	PROPN
admet-942	811	27	,	,	PUNCT
admet-942	811	28	m.	m.	NOUN
admet-942	811	29	kasendra	kasendra	PROPN
admet-942	811	30	,	,	PUNCT
admet-942	811	31	c.	c.	PROPN
admet-942	811	32	lucchesi	lucchesi	PROPN
admet-942	811	33	,	,	PUNCT
admet-942	811	34	j.	j.	PROPN
admet-942	811	35	kerns	kerns	PROPN
admet-942	811	36	,	,	PUNCT
admet-942	811	37	n.	n.	PROPN
admet-942	811	38	wen	wen	PROPN
admet-942	811	39	,	,	PUNCT
admet-942	811	40	w.r	w.r	PROPN
admet-942	811	41	.	.	PROPN
admet-942	811	42	spivia	spivia	PROPN
admet-942	811	43	,	,	PUNCT
admet-942	811	44	z.	z.	PROPN
admet-942	811	45	chen	chen	PROPN
admet-942	811	46	,	,	PUNCT
admet-942	811	47	j.	j.	PROPN
admet-942	811	48	van	van	PROPN
admet-942	811	49	eyk	eyk	PROPN
admet-942	811	50	,	,	PUNCT
admet-942	811	51	c.n	c.n	PROPN
admet-942	811	52	.	.	PROPN
admet-942	811	53	svendsen	svendsen	PROPN
admet-942	811	54	.	.	PUNCT
admet-942	812	1	human	human	ADJ
admet-942	812	2	ipscderived	ipscderive	VERB
admet-942	812	3	blood	blood	NOUN
admet-942	812	4	-	-	PUNCT
admet-942	812	5	brain	brain	NOUN
admet-942	812	6	barrier	barrier	NOUN
admet-942	812	7	chips	chip	NOUN
admet-942	812	8	enable	enable	VERB
admet-942	812	9	disease	disease	NOUN
admet-942	812	10	modeling	modeling	NOUN
admet-942	812	11	and	and	CCONJ
admet-942	812	12	personalized	personalized	ADJ
admet-942	812	13	medicine	medicine	NOUN
admet-942	812	14	applications	application	NOUN
admet-942	812	15	.	.	PUNCT
admet-942	813	1	cell	cell	NOUN
admet-942	813	2	stem	stem	NOUN
admet-942	813	3	cell	cell	NOUN
admet-942	813	4	24	24	NUM
admet-942	813	5	(	(	PUNCT
admet-942	813	6	2019	2019	NUM
admet-942	813	7	)	)	PUNCT
admet-942	813	8	995	995	NUM
admet-942	813	9	-	-	SYM
admet-942	813	10	1005	1005	NUM
admet-942	813	11	.	.	PUNCT
admet-942	814	1	https://doi.org/10.1016/j.stem.2019.05.011	https://doi.org/10.1016/j.stem.2019.05.011	ADJ
admet-942	814	2	.	.	PUNCT
admet-942	815	1	[	[	X
admet-942	815	2	75	75	NUM
admet-942	815	3	]	]	PUNCT
admet-942	815	4	k.	k.	PROPN
admet-942	815	5	song	song	PROPN
admet-942	815	6	,	,	PUNCT
admet-942	815	7	g.	g.	PROPN
admet-942	815	8	li	li	PROPN
admet-942	815	9	,	,	PUNCT
admet-942	815	10	x.	x.	PROPN
admet-942	815	11	zu	zu	PROPN
admet-942	815	12	,	,	PUNCT
admet-942	815	13	z.	z.	PROPN
admet-942	815	14	du	du	PROPN
admet-942	815	15	,	,	PUNCT
admet-942	815	16	l.	l.	PROPN
admet-942	815	17	liu	liu	PROPN
admet-942	815	18	,	,	PUNCT
admet-942	815	19	z.	z.	PROPN
admet-942	815	20	hu	hu	PROPN
admet-942	815	21	.	.	PUNCT
admet-942	816	1	the	the	DET
admet-942	816	2	fabrication	fabrication	NOUN
admet-942	816	3	and	and	CCONJ
admet-942	816	4	application	application	NOUN
admet-942	816	5	mechanism	mechanism	NOUN
admet-942	816	6	of	of	ADP
admet-942	816	7	microfluidic	microfluidic	ADJ
admet-942	816	8	systems	system	NOUN
admet-942	816	9	for	for	ADP
admet-942	816	10	high	high	ADJ
admet-942	816	11	throughput	throughput	NOUN
admet-942	816	12	biomedical	biomedical	ADJ
admet-942	816	13	screening	screening	NOUN
admet-942	816	14	:	:	PUNCT
admet-942	816	15	a	a	DET
admet-942	816	16	review	review	NOUN
admet-942	816	17	.	.	PUNCT
admet-942	817	1	micromachines	micromachine	NOUN
admet-942	817	2	11	11	NUM
admet-942	817	3	(	(	PUNCT
admet-942	817	4	2020	2020	NUM
admet-942	817	5	)	)	PUNCT
admet-942	817	6	297	297	NUM
admet-942	817	7	.	.	PUNCT
admet-942	818	1	https://doi.org/10.3390/mi11030297	https://doi.org/10.3390/mi11030297	PROPN
admet-942	818	2	.	.	PUNCT
admet-942	819	1	https://doi.org/10.1016/j.stem.2017.08.016	https://doi.org/10.1016/j.stem.2017.08.016	PROPN
admet-942	819	2	https://doi.org/10.1016/j.gene.2018.11.058	https://doi.org/10.1016/j.gene.2018.11.058	NUM
admet-942	819	3	https://doi.org/10.1016/j.gene.2018.11.058	https://doi.org/10.1016/j.gene.2018.11.058	PROPN
admet-942	819	4	https://doi.org/10.3389/fbioe.2019.00100	https://doi.org/10.3389/fbioe.2019.00100	PROPN
admet-942	819	5	https://doi.org/10.1016/j.biotechadv.2016.12.002	https://doi.org/10.1016/j.biotechadv.2016.12.002	NOUN
admet-942	819	6	https://doi.org/10.1039/c9lc00861f	https://doi.org/10.1039/c9lc00861f	PROPN
admet-942	819	7	https://doi.org/10.1039/c9lc00861f	https://doi.org/10.1039/c9lc00861f	PROPN
admet-942	819	8	https://doi.org/10.1039/c4lc00371c	https://doi.org/10.1039/c4lc00371c	NUM
admet-942	819	9	https://doi.org/10.1016/j.trac.2019.06.023	https://doi.org/10.1016/j.trac.2019.06.023	PROPN
admet-942	819	10	https://doi.org/10.1021/ar4002608	https://doi.org/10.1021/ar4002608	PROPN
admet-942	819	11	https://doi.org/10.1021/ar4002608	https://doi.org/10.1021/ar4002608	VERB
admet-942	819	12	https://doi.org/10.1016/j.sna.2019.111704	https://doi.org/10.1016/j.sna.2019.111704	VERB
admet-942	819	13	https://doi.org/10.1016/j.sna.2019.111704	https://doi.org/10.1016/j.sna.2019.111704	VERB
admet-942	819	14	https://doi.org/10.1016/j.stem.2019.05.011	https://doi.org/10.1016/j.stem.2019.05.011	PROPN
admet-942	819	15	admet	admet	X
admet-942	819	16	&	&	CCONJ
admet-942	819	17	dmpk	dmpk	PROPN
admet-942	819	18	9(2	9(2	NUM
admet-942	819	19	)	)	PUNCT
admet-942	819	20	(	(	PUNCT
admet-942	819	21	2021	2021	NUM
admet-942	819	22	)	)	PUNCT
admet-942	819	23	111	111	NUM
admet-942	819	24	-	-	SYM
admet-942	819	25	141	141	NUM
admet-942	819	26	organ	organ	NOUN
admet-942	819	27	-	-	PUNCT
admet-942	819	28	on	on	ADP
admet-942	819	29	-	-	PUNCT
admet-942	819	30	a	a	DET
admet-942	819	31	-	-	PUNCT
admet-942	819	32	chip	chip	NOUN
admet-942	819	33	systems	system	NOUN
admet-942	819	34	for	for	ADP
admet-942	819	35	new	new	ADJ
admet-942	819	36	drugs	drug	NOUN
admet-942	819	37	development	development	NOUN
admet-942	819	38	doi	doi	PROPN
admet-942	819	39	:	:	PUNCT
admet-942	819	40	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	NOUN
admet-942	819	41	137	137	NUM
admet-942	819	42	[	[	SYM
admet-942	819	43	76	76	NUM
admet-942	819	44	]	]	X
admet-942	819	45	s.	s.	PROPN
admet-942	819	46	cho	cho	PROPN
admet-942	819	47	,	,	PUNCT
admet-942	819	48	a.	a.	PROPN
admet-942	819	49	islas	islas	PROPN
admet-942	819	50	-	-	PUNCT
admet-942	819	51	robles	robles	PROPN
admet-942	819	52	,	,	PUNCT
admet-942	819	53	a.m.	a.m.	PROPN
admet-942	819	54	nicolini	nicolini	PROPN
admet-942	819	55	,	,	PUNCT
admet-942	819	56	t.j	t.j	PROPN
admet-942	819	57	.	.	PROPN
admet-942	819	58	monks	monks	PROPN
admet-942	819	59	,	,	PUNCT
admet-942	819	60	j.y	j.y	PROPN
admet-942	819	61	.	.	PROPN
admet-942	819	62	yoon	yoon	PROPN
admet-942	819	63	.	.	PUNCT
admet-942	820	1	in	in	ADP
admet-942	820	2	situ	situ	NOUN
admet-942	820	3	,	,	PUNCT
admet-942	820	4	dual	dual	ADJ
admet-942	820	5	-	-	PUNCT
admet-942	820	6	mode	mode	NOUN
admet-942	820	7	monitoring	monitoring	NOUN
admet-942	820	8	of	of	ADP
admet-942	820	9	organ	organ	NOUN
admet-942	820	10	-	-	PUNCT
admet-942	820	11	ona	ona	NOUN
admet-942	820	12	-	-	PUNCT
admet-942	820	13	chip	chip	NOUN
admet-942	820	14	with	with	ADP
admet-942	820	15	smartphone	smartphone	NOUN
admet-942	820	16	-	-	PUNCT
admet-942	820	17	based	base	VERB
admet-942	820	18	fluorescence	fluorescence	NOUN
admet-942	820	19	microscope	microscope	NOUN
admet-942	820	20	.	.	PUNCT
admet-942	821	1	biosensors	biosensor	NOUN
admet-942	821	2	and	and	CCONJ
admet-942	821	3	bioelectronics	bioelectronic	NOUN
admet-942	821	4	86	86	NUM
admet-942	821	5	(	(	PUNCT
admet-942	821	6	2016	2016	NUM
admet-942	821	7	)	)	PUNCT
admet-942	821	8	697	697	NUM
admet-942	821	9	-	-	SYM
admet-942	821	10	705	705	NUM
admet-942	821	11	.	.	PUNCT
admet-942	822	1	https://doi.org/10.1016/j.bios.2016.07.015	https://doi.org/10.1016/j.bios.2016.07.015	NUM
admet-942	822	2	.	.	PUNCT
admet-942	823	1	[	[	X
admet-942	823	2	77	77	NUM
admet-942	823	3	]	]	X
admet-942	823	4	f.	f.	PROPN
admet-942	823	5	sivandzade	sivandzade	PROPN
admet-942	823	6	,	,	PUNCT
admet-942	823	7	l.	l.	PROPN
admet-942	823	8	cucullo	cucullo	PROPN
admet-942	823	9	.	.	PUNCT
admet-942	824	1	in	in	ADP
admet-942	824	2	-	-	PUNCT
admet-942	824	3	vitro	vitro	X
admet-942	824	4	blood	blood	NOUN
admet-942	824	5	–	–	PUNCT
admet-942	824	6	brain	brain	NOUN
admet-942	824	7	barrier	barrier	NOUN
admet-942	824	8	modeling	modeling	NOUN
admet-942	824	9	:	:	PUNCT
admet-942	824	10	a	a	DET
admet-942	824	11	review	review	NOUN
admet-942	824	12	of	of	ADP
admet-942	824	13	modern	modern	ADJ
admet-942	824	14	and	and	CCONJ
admet-942	824	15	fastadvancing	fastadvance	VERB
admet-942	824	16	technologies	technology	NOUN
admet-942	824	17	.	.	PUNCT
admet-942	825	1	journal	journal	NOUN
admet-942	825	2	of	of	ADP
admet-942	825	3	cerebral	cerebral	ADJ
admet-942	825	4	blood	blood	NOUN
admet-942	825	5	flow	flow	NOUN
admet-942	825	6	and	and	CCONJ
admet-942	825	7	metabolism	metabolism	NOUN
admet-942	825	8	38	38	NUM
admet-942	825	9	(	(	PUNCT
admet-942	825	10	2018	2018	NUM
admet-942	825	11	)	)	PUNCT
admet-942	825	12	1667	1667	NUM
admet-942	825	13	-	-	SYM
admet-942	825	14	1681	1681	NUM
admet-942	825	15	.	.	PUNCT
admet-942	826	1	https://doi.org/10.1177/0271678x18788769	https://doi.org/10.1177/0271678x18788769	NOUN
admet-942	826	2	.	.	PUNCT
admet-942	827	1	[	[	X
admet-942	827	2	78	78	NUM
admet-942	827	3	]	]	PUNCT
admet-942	827	4	b.	b.	PROPN
admet-942	827	5	peng	peng	PROPN
admet-942	827	6	,	,	PUNCT
admet-942	827	7	z.	z.	PROPN
admet-942	827	8	tong	tong	PROPN
admet-942	827	9	,	,	PUNCT
admet-942	827	10	w.y	w.y	PROPN
admet-942	827	11	.	.	PUNCT
admet-942	828	1	tong	tong	PROPN
admet-942	828	2	,	,	PUNCT
admet-942	828	3	p.j	p.j	PROPN
admet-942	828	4	.	.	PROPN
admet-942	828	5	pasic	pasic	PROPN
admet-942	828	6	,	,	PUNCT
admet-942	828	7	a.	a.	NOUN
admet-942	828	8	oddo	oddo	NOUN
admet-942	828	9	,	,	PUNCT
admet-942	828	10	y.	y.	PROPN
admet-942	828	11	dai	dai	PROPN
admet-942	828	12	,	,	PUNCT
admet-942	828	13	m.	m.	PROPN
admet-942	828	14	luo	luo	PROPN
admet-942	828	15	,	,	PUNCT
admet-942	828	16	j.	j.	PROPN
admet-942	828	17	frescene	frescene	PROPN
admet-942	828	18	,	,	PUNCT
admet-942	828	19	n.g	n.g	PROPN
admet-942	828	20	.	.	PROPN
admet-942	828	21	welch	welch	PROPN
admet-942	828	22	,	,	PUNCT
admet-942	828	23	c.d	c.d	PROPN
admet-942	828	24	.	.	PROPN
admet-942	828	25	easton	easton	PROPN
admet-942	828	26	,	,	PUNCT
admet-942	828	27	h.	h.	PROPN
admet-942	828	28	thissen	thissen	PROPN
admet-942	828	29	,	,	PUNCT
admet-942	828	30	n.h	n.h	PROPN
admet-942	828	31	.	.	PROPN
admet-942	828	32	voelcker	voelcker	PROPN
admet-942	828	33	.	.	PUNCT
admet-942	829	1	in	in	ADP
admet-942	829	2	situ	situ	ADJ
admet-942	829	3	surface	surface	NOUN
admet-942	829	4	modification	modification	NOUN
admet-942	829	5	of	of	ADP
admet-942	829	6	microfluidic	microfluidic	ADJ
admet-942	829	7	blood	blood	NOUN
admet-942	829	8	-	-	PUNCT
admet-942	829	9	brain	brain	NOUN
admet-942	829	10	-	-	PUNCT
admet-942	829	11	barriers	barrier	NOUN
admet-942	829	12	for	for	ADP
admet-942	829	13	improved	improved	ADJ
admet-942	829	14	screening	screening	NOUN
admet-942	829	15	of	of	ADP
admet-942	829	16	small	small	ADJ
admet-942	829	17	molecules	molecule	NOUN
admet-942	829	18	and	and	CCONJ
admet-942	829	19	nanoparticles	nanoparticle	NOUN
admet-942	829	20	.	.	PUNCT
admet-942	830	1	acs	acs	PROPN
admet-942	830	2	applied	apply	VERB
admet-942	830	3	materials	material	NOUN
admet-942	830	4	and	and	CCONJ
admet-942	830	5	interfaces	interface	NOUN
admet-942	830	6	12	12	NUM
admet-942	830	7	(	(	PUNCT
admet-942	830	8	2020	2020	NUM
admet-942	830	9	)	)	PUNCT
admet-942	830	10	56753	56753	NUM
admet-942	830	11	-	-	SYM
admet-942	830	12	56766	56766	NUM
admet-942	830	13	.	.	PUNCT
admet-942	831	1	https://doi.org/10.1021/acsami.0c17102	https://doi.org/10.1021/acsami.0c17102	NOUN
admet-942	831	2	.	.	PUNCT
admet-942	832	1	[	[	X
admet-942	832	2	79	79	NUM
admet-942	832	3	]	]	X
admet-942	832	4	l.	l.	PROPN
admet-942	832	5	tong	tong	PROPN
admet-942	832	6	,	,	PUNCT
admet-942	832	7	m.	m.	NOUN
admet-942	832	8	mozneb	mozneb	PROPN
admet-942	832	9	,	,	PUNCT
admet-942	832	10	e.	e.	PROPN
admet-942	832	11	bravo	bravo	PROPN
admet-942	832	12	,	,	PUNCT
admet-942	832	13	v.	v.	ADP
admet-942	832	14	ferrando	ferrando	PROPN
admet-942	832	15	,	,	PUNCT
admet-942	832	16	c.z	c.z	PROPN
admet-942	832	17	.	.	PUNCT
admet-942	833	1	li	li	PROPN
admet-942	833	2	.	.	PROPN
admet-942	834	1	whole	whole	ADJ
admet-942	834	2	cell	cell	NOUN
admet-942	834	3	analysis	analysis	NOUN
admet-942	834	4	ranging	range	VERB
admet-942	834	5	from	from	ADP
admet-942	834	6	intercellular	intercellular	ADJ
admet-942	834	7	assay	assay	NOUN
admet-942	834	8	to	to	PART
admet-942	834	9	organ	organ	VERB
admet-942	834	10	on	on	ADP
admet-942	834	11	a	a	DET
admet-942	834	12	chip	chip	NOUN
admet-942	834	13	.	.	PUNCT
admet-942	835	1	trends	trend	NOUN
admet-942	835	2	in	in	ADP
admet-942	835	3	analytical	analytical	ADJ
admet-942	835	4	chemistry	chemistry	NOUN
admet-942	835	5	117	117	NUM
admet-942	835	6	(	(	PUNCT
admet-942	835	7	2019	2019	NUM
admet-942	835	8	)	)	PUNCT
admet-942	835	9	157	157	NUM
admet-942	835	10	-	-	SYM
admet-942	835	11	165	165	NUM
admet-942	835	12	.	.	PUNCT
admet-942	836	1	https://doi.org/10.1016/j.trac.2019.05.021	https://doi.org/10.1016/j.trac.2019.05.021	NOUN
admet-942	836	2	.	.	PUNCT
admet-942	837	1	[	[	X
admet-942	837	2	80	80	NUM
admet-942	837	3	]	]	X
admet-942	837	4	m.j.c	m.j.c	PROPN
admet-942	837	5	.	.	PUNCT
admet-942	837	6	santbergen	santbergen	PROPN
admet-942	837	7	,	,	PUNCT
admet-942	837	8	m.	m.	NOUN
admet-942	837	9	van	van	PROPN
admet-942	837	10	der	der	PROPN
admet-942	837	11	zande	zande	NOUN
admet-942	837	12	,	,	PUNCT
admet-942	837	13	h.	h.	PROPN
admet-942	837	14	bouwmeester	bouwmeester	PROPN
admet-942	837	15	,	,	PUNCT
admet-942	837	16	m.w.f	m.w.f	PROPN
admet-942	837	17	.	.	PUNCT
admet-942	837	18	nielen	nielen	PROPN
admet-942	837	19	.	.	PUNCT
admet-942	838	1	online	online	ADV
admet-942	838	2	and	and	CCONJ
admet-942	838	3	in	in	ADP
admet-942	838	4	situ	situ	ADJ
admet-942	838	5	analysis	analysis	NOUN
admet-942	838	6	of	of	ADP
admet-942	838	7	organs	organ	NOUN
admet-942	838	8	-	-	PUNCT
admet-942	838	9	on	on	ADP
admet-942	838	10	-	-	PUNCT
admet-942	838	11	a	a	DET
admet-942	838	12	-	-	PUNCT
admet-942	838	13	chip	chip	NOUN
admet-942	838	14	.	.	PUNCT
admet-942	839	1	trends	trend	NOUN
admet-942	839	2	in	in	ADP
admet-942	839	3	analytical	analytical	ADJ
admet-942	839	4	chemistry	chemistry	NOUN
admet-942	839	5	115	115	NUM
admet-942	839	6	(	(	PUNCT
admet-942	839	7	2019	2019	NUM
admet-942	839	8	)	)	PUNCT
admet-942	839	9	138	138	NUM
admet-942	839	10	-	-	SYM
admet-942	839	11	146	146	NUM
admet-942	839	12	.	.	PUNCT
admet-942	839	13	https://doi.org/10.1016/j.trac.2019.04.006	https://doi.org/10.1016/j.trac.2019.04.006	PROPN
admet-942	839	14	.	.	PUNCT
admet-942	840	1	[	[	X
admet-942	840	2	81	81	NUM
admet-942	840	3	]	]	X
admet-942	840	4	n.f	n.f	PROPN
admet-942	840	5	.	.	PROPN
admet-942	840	6	huang	huang	PROPN
admet-942	840	7	,	,	PUNCT
admet-942	840	8	o.	o.	PROPN
admet-942	840	9	chaudhuri	chaudhuri	PROPN
admet-942	840	10	,	,	PUNCT
admet-942	840	11	p.	p.	PROPN
admet-942	840	12	cahan	cahan	PROPN
admet-942	840	13	,	,	PUNCT
admet-942	840	14	a.	a.	PROPN
admet-942	840	15	wang	wang	PROPN
admet-942	840	16	,	,	PUNCT
admet-942	840	17	a.j	a.j	PROPN
admet-942	840	18	.	.	PROPN
admet-942	840	19	engler	engler	PROPN
admet-942	840	20	,	,	PUNCT
admet-942	840	21	y.	y.	PROPN
admet-942	840	22	wang	wang	PROPN
admet-942	840	23	,	,	PUNCT
admet-942	840	24	s.	s.	PROPN
admet-942	840	25	kumar	kumar	PROPN
admet-942	840	26	,	,	PUNCT
admet-942	840	27	a.	a.	NOUN
admet-942	840	28	khademhosseini	khademhosseini	PROPN
admet-942	840	29	,	,	PUNCT
admet-942	840	30	s.	s.	PROPN
admet-942	840	31	li	li	PROPN
admet-942	840	32	.	.	PUNCT
admet-942	840	33	multi	multi	ADJ
admet-942	840	34	-	-	ADJ
admet-942	840	35	scale	scale	ADJ
admet-942	840	36	cellular	cellular	ADJ
admet-942	840	37	engineering	engineering	NOUN
admet-942	840	38	:	:	PUNCT
admet-942	840	39	from	from	ADP
admet-942	840	40	molecules	molecule	NOUN
admet-942	840	41	to	to	AUX
admet-942	840	42	organ	organ	NOUN
admet-942	840	43	-	-	PUNCT
admet-942	840	44	on	on	ADP
admet-942	840	45	-	-	PUNCT
admet-942	840	46	a	a	DET
admet-942	840	47	-	-	PUNCT
admet-942	840	48	chip	chip	NOUN
admet-942	840	49	.	.	PUNCT
admet-942	841	1	apl	apl	PROPN
admet-942	841	2	bioengineering	bioengineere	VERB
admet-942	841	3	4	4	NUM
admet-942	841	4	(	(	PUNCT
admet-942	841	5	2020	2020	NUM
admet-942	841	6	)	)	PUNCT
admet-942	841	7	010906	010906	NUM
admet-942	841	8	.	.	PUNCT
admet-942	842	1	https://doi.org/10.1063/1.5129788	https://doi.org/10.1063/1.5129788	PROPN
admet-942	842	2	.	.	PUNCT
admet-942	843	1	[	[	X
admet-942	843	2	82	82	NUM
admet-942	843	3	]	]	X
admet-942	843	4	m.	m.	NOUN
admet-942	843	5	abulaiti	abulaiti	PROPN
admet-942	843	6	,	,	PUNCT
admet-942	843	7	y.	y.	PROPN
admet-942	843	8	yalikun	yalikun	PROPN
admet-942	843	9	,	,	PUNCT
admet-942	843	10	k.	k.	PROPN
admet-942	843	11	murata	murata	PROPN
admet-942	843	12	,	,	PUNCT
admet-942	843	13	a.	a.	NOUN
admet-942	843	14	sato	sato	PROPN
admet-942	843	15	,	,	PUNCT
admet-942	843	16	m.m	m.m	PROPN
admet-942	843	17	.	.	PROPN
admet-942	843	18	sami	sami	PROPN
admet-942	843	19	,	,	PUNCT
admet-942	843	20	y.	y.	PROPN
admet-942	843	21	sasaki	sasaki	PROPN
admet-942	843	22	,	,	PUNCT
admet-942	843	23	y.	y.	PROPN
admet-942	843	24	fujiwara	fujiwara	PROPN
admet-942	843	25	,	,	PUNCT
admet-942	843	26	k.	k.	PROPN
admet-942	843	27	minatoya	minatoya	PROPN
admet-942	843	28	,	,	PUNCT
admet-942	843	29	y.	y.	PROPN
admet-942	843	30	shiba	shiba	PROPN
admet-942	843	31	,	,	PUNCT
admet-942	843	32	y.	y.	PROPN
admet-942	843	33	tanaka	tanaka	PROPN
admet-942	843	34	,	,	PUNCT
admet-942	843	35	h.	h.	PROPN
admet-942	843	36	masumoto	masumoto	PROPN
admet-942	843	37	.	.	PUNCT
admet-942	844	1	establishment	establishment	NOUN
admet-942	844	2	of	of	ADP
admet-942	844	3	a	a	DET
admet-942	844	4	heart	heart	NOUN
admet-942	844	5	-	-	PUNCT
admet-942	844	6	on	on	ADP
admet-942	844	7	-	-	PUNCT
admet-942	844	8	a	a	DET
admet-942	844	9	-	-	PUNCT
admet-942	844	10	chip	chip	NOUN
admet-942	844	11	microdevice	microdevice	NOUN
admet-942	844	12	based	base	VERB
admet-942	844	13	on	on	ADP
admet-942	844	14	human	human	ADJ
admet-942	844	15	ips	ips	NOUN
admet-942	844	16	cells	cell	NOUN
admet-942	844	17	for	for	ADP
admet-942	844	18	the	the	DET
admet-942	844	19	evaluation	evaluation	NOUN
admet-942	844	20	of	of	ADP
admet-942	844	21	human	human	ADJ
admet-942	844	22	heart	heart	NOUN
admet-942	844	23	tissue	tissue	NOUN
admet-942	844	24	function	function	NOUN
admet-942	844	25	.	.	PUNCT
admet-942	845	1	scientific	scientific	ADJ
admet-942	845	2	reports	report	NOUN
admet-942	845	3	10	10	NUM
admet-942	845	4	(	(	PUNCT
admet-942	845	5	2020	2020	NUM
admet-942	845	6	)	)	PUNCT
admet-942	845	7	19201	19201	NUM
admet-942	845	8	.	.	PUNCT
admet-942	846	1	https://doi.org/10.1038/s41598-020-76062-w	https://doi.org/10.1038/s41598-020-76062-w	ADV
admet-942	846	2	.	.	PUNCT
admet-942	847	1	[	[	X
admet-942	847	2	83	83	NUM
admet-942	847	3	]	]	SYM
admet-942	847	4	m.c	m.c	PROPN
admet-942	847	5	.	.	PROPN
admet-942	847	6	comes	come	VERB
admet-942	847	7	,	,	PUNCT
admet-942	847	8	a.	a.	NOUN
admet-942	847	9	mencattini	mencattini	PROPN
admet-942	847	10	,	,	PUNCT
admet-942	847	11	d.	d.	PROPN
admet-942	847	12	di	di	PROPN
admet-942	847	13	giuseppe	giuseppe	PROPN
admet-942	847	14	,	,	PUNCT
admet-942	847	15	j.	j.	PROPN
admet-942	847	16	filippi	filippi	PROPN
admet-942	847	17	,	,	PUNCT
admet-942	847	18	m.d	m.d	PROPN
admet-942	847	19	.	.	PROPN
admet-942	847	20	orazio	orazio	PROPN
admet-942	847	21	,	,	PUNCT
admet-942	847	22	p.	p.	NOUN
admet-942	847	23	casti	casti	PROPN
admet-942	847	24	,	,	PUNCT
admet-942	847	25	f.	f.	PROPN
admet-942	847	26	corsi	corsi	PROPN
admet-942	847	27	,	,	PUNCT
admet-942	847	28	l.	l.	PROPN
admet-942	847	29	ghibelli	ghibelli	PROPN
admet-942	847	30	,	,	PUNCT
admet-942	847	31	c.	c.	PROPN
admet-942	847	32	di	di	PROPN
admet-942	847	33	natale	natale	PROPN
admet-942	847	34	,	,	PUNCT
admet-942	847	35	e.	e.	PROPN
admet-942	847	36	martinelli	martinelli	PROPN
admet-942	847	37	.	.	PUNCT
admet-942	848	1	a	a	DET
admet-942	848	2	camera	camera	NOUN
admet-942	848	3	sensors	sensor	NOUN
admet-942	848	4	-	-	PUNCT
admet-942	848	5	based	base	VERB
admet-942	848	6	system	system	NOUN
admet-942	848	7	to	to	PART
admet-942	848	8	study	study	VERB
admet-942	848	9	drug	drug	NOUN
admet-942	848	10	cancer	cancer	NOUN
admet-942	848	11	cells	cell	NOUN
admet-942	848	12	.	.	PUNCT
admet-942	849	1	sensors	sensor	NOUN
admet-942	849	2	20	20	NUM
admet-942	849	3	(	(	PUNCT
admet-942	849	4	2020	2020	NUM
admet-942	849	5	)	)	PUNCT
admet-942	849	6	1531	1531	NUM
admet-942	849	7	-	-	SYM
admet-942	849	8	1556	1556	NUM
admet-942	849	9	.	.	PUNCT
admet-942	850	1	https://doi.org/10.3390/s20051531	https://doi.org/10.3390/s20051531	NUM
admet-942	850	2	.	.	PUNCT
admet-942	851	1	[	[	X
admet-942	851	2	84	84	NUM
admet-942	851	3	]	]	X
admet-942	851	4	n.s	n.s	PROPN
admet-942	851	5	.	.	PROPN
admet-942	851	6	bhise	bhise	PROPN
admet-942	851	7	,	,	PUNCT
admet-942	851	8	j.	j.	PROPN
admet-942	851	9	ribas	ribas	PROPN
admet-942	851	10	,	,	PUNCT
admet-942	851	11	v.	v.	ADP
admet-942	851	12	manoharan	manoharan	NOUN
admet-942	851	13	,	,	PUNCT
admet-942	851	14	y.s	y.s	PROPN
admet-942	851	15	.	.	PROPN
admet-942	851	16	zhang	zhang	PROPN
admet-942	851	17	,	,	PUNCT
admet-942	851	18	a.	a.	PROPN
admet-942	851	19	polini	polini	PROPN
admet-942	851	20	,	,	PUNCT
admet-942	851	21	s.	s.	PROPN
admet-942	851	22	massa	massa	PROPN
admet-942	851	23	,	,	PUNCT
admet-942	851	24	m.r	m.r	PROPN
admet-942	851	25	.	.	PROPN
admet-942	851	26	dokmeci	dokmeci	PROPN
admet-942	851	27	,	,	PUNCT
admet-942	851	28	a.	a.	NOUN
admet-942	851	29	khademhosseini	khademhosseini	PROPN
admet-942	851	30	.	.	PUNCT
admet-942	851	31	organ	organ	NOUN
admet-942	851	32	-	-	PUNCT
admet-942	851	33	on	on	ADP
admet-942	851	34	-	-	PUNCT
admet-942	851	35	a	a	DET
admet-942	851	36	-	-	PUNCT
admet-942	851	37	chip	chip	NOUN
admet-942	851	38	platforms	platform	NOUN
admet-942	851	39	for	for	ADP
admet-942	851	40	studying	study	VERB
admet-942	851	41	drug	drug	NOUN
admet-942	851	42	delivery	delivery	NOUN
admet-942	851	43	systems	system	NOUN
admet-942	851	44	.	.	PUNCT
admet-942	852	1	journal	journal	PROPN
admet-942	852	2	of	of	ADP
admet-942	852	3	controlled	control	VERB
admet-942	852	4	release	release	NOUN
admet-942	852	5	190	190	NUM
admet-942	852	6	(	(	PUNCT
admet-942	852	7	2014	2014	NUM
admet-942	852	8	)	)	PUNCT
admet-942	852	9	82	82	NUM
admet-942	852	10	-	-	SYM
admet-942	852	11	93	93	NUM
admet-942	852	12	.	.	PUNCT
admet-942	853	1	https://doi.org/10.1016/j.jconrel.2014.05.004	https://doi.org/10.1016/j.jconrel.2014.05.004	NOUN
admet-942	853	2	.	.	PUNCT
admet-942	854	1	[	[	X
admet-942	854	2	85	85	NUM
admet-942	854	3	]	]	PUNCT
admet-942	854	4	m.	m.	NOUN
admet-942	854	5	rimann	rimann	PROPN
admet-942	854	6	,	,	PUNCT
admet-942	854	7	e.	e.	PROPN
admet-942	854	8	bono	bono	PROPN
admet-942	854	9	,	,	PUNCT
admet-942	854	10	h.	h.	PROPN
admet-942	854	11	annaheim	annaheim	PROPN
admet-942	854	12	,	,	PUNCT
admet-942	854	13	m.	m.	PROPN
admet-942	854	14	bleisch	bleisch	PROPN
admet-942	854	15	,	,	PUNCT
admet-942	854	16	u.	u.	PROPN
admet-942	854	17	graf	graf	PROPN
admet-942	854	18	-	-	PUNCT
admet-942	854	19	hausner	hausner	NOUN
admet-942	854	20	.	.	PUNCT
admet-942	855	1	standardized	standardize	VERB
admet-942	855	2	3d	3d	NUM
admet-942	855	3	bioprinting	bioprinting	NOUN
admet-942	855	4	of	of	ADP
admet-942	855	5	soft	soft	ADJ
admet-942	855	6	tissue	tissue	NOUN
admet-942	855	7	models	model	NOUN
admet-942	855	8	with	with	ADP
admet-942	855	9	human	human	ADJ
admet-942	855	10	primary	primary	ADJ
admet-942	855	11	cells	cell	NOUN
admet-942	855	12	.	.	PUNCT
admet-942	856	1	journal	journal	PROPN
admet-942	856	2	of	of	ADP
admet-942	856	3	laboratory	laboratory	NOUN
admet-942	856	4	automation	automation	NOUN
admet-942	856	5	21	21	NUM
admet-942	856	6	(	(	PUNCT
admet-942	856	7	2016	2016	NUM
admet-942	856	8	)	)	PUNCT
admet-942	856	9	496	496	NUM
admet-942	856	10	-	-	SYM
admet-942	856	11	509	509	NUM
admet-942	856	12	.	.	PUNCT
admet-942	857	1	https://doi.org/10.1177/2211068214567146	https://doi.org/10.1177/2211068214567146	NOUN
admet-942	857	2	.	.	PUNCT
admet-942	858	1	[	[	X
admet-942	858	2	86	86	NUM
admet-942	858	3	]	]	X
admet-942	858	4	c.	c.	PROPN
admet-942	858	5	liu	liu	PROPN
admet-942	858	6	,	,	PUNCT
admet-942	858	7	a.	a.	NOUN
admet-942	858	8	oikonomopoulos	oikonomopoulos	PROPN
admet-942	858	9	,	,	PUNCT
admet-942	858	10	n.	n.	PROPN
admet-942	858	11	sayed	sayed	PROPN
admet-942	858	12	,	,	PUNCT
admet-942	858	13	j.c	j.c	PROPN
admet-942	858	14	.	.	PROPN
admet-942	858	15	wu	wu	PROPN
admet-942	858	16	.	.	PUNCT
admet-942	859	1	modeling	model	VERB
admet-942	859	2	human	human	ADJ
admet-942	859	3	diseases	disease	NOUN
admet-942	859	4	with	with	ADP
admet-942	859	5	induced	induced	ADJ
admet-942	859	6	pluripotent	pluripotent	ADJ
admet-942	859	7	stem	stem	NOUN
admet-942	859	8	cells	cell	NOUN
admet-942	859	9	:	:	PUNCT
admet-942	859	10	from	from	ADP
admet-942	859	11	2d	2d	NUM
admet-942	859	12	to	to	ADP
admet-942	859	13	3d	3d	NUM
admet-942	859	14	and	and	CCONJ
admet-942	859	15	beyond	beyond	ADP
admet-942	859	16	.	.	PUNCT
admet-942	860	1	development	development	NOUN
admet-942	860	2	(	(	PUNCT
admet-942	860	3	cambridge	cambridge	PROPN
admet-942	860	4	)	)	PUNCT
admet-942	860	5	145	145	NUM
admet-942	860	6	(	(	PUNCT
admet-942	860	7	2018	2018	NUM
admet-942	860	8	)	)	PUNCT
admet-942	860	9	1	1	NUM
admet-942	860	10	-	-	SYM
admet-942	860	11	6	6	NUM
admet-942	860	12	.	.	PUNCT
admet-942	861	1	https://doi.org/10.1242/dev.156166	https://doi.org/10.1242/dev.156166	NOUN
admet-942	861	2	.	.	PUNCT
admet-942	862	1	[	[	X
admet-942	862	2	87	87	NUM
admet-942	862	3	]	]	X
admet-942	862	4	c.g	c.g	PROPN
admet-942	862	5	.	.	PROPN
admet-942	862	6	musah	musah	PROPN
admet-942	862	7	s	s	PROPN
admet-942	862	8	,	,	PUNCT
admet-942	862	9	dimitrakakis	dimitrakaki	NOUN
admet-942	862	10	n	n	CCONJ
admet-942	862	11	,	,	PUNCT
admet-942	862	12	camacho	camacho	PROPN
admet-942	862	13	dm	dm	PROPN
admet-942	862	14	,	,	PUNCT
admet-942	862	15	i.	i.	PROPN
admet-942	862	16	de	de	PROPN
admet-942	862	17	.	.	PROPN
admet-942	862	18	directed	direct	VERB
admet-942	862	19	differentiation	differentiation	NOUN
admet-942	862	20	of	of	ADP
admet-942	862	21	human	human	ADJ
admet-942	862	22	induced	induced	ADJ
admet-942	862	23	pluripotent	pluripotent	ADJ
admet-942	862	24	stem	stem	NOUN
admet-942	862	25	cells	cell	NOUN
admet-942	862	26	into	into	ADP
admet-942	862	27	mature	mature	ADJ
admet-942	862	28	kidney	kidney	NOUN
admet-942	862	29	podocytes	podocyte	NOUN
admet-942	862	30	and	and	CCONJ
admet-942	862	31	establishment	establishment	NOUN
admet-942	862	32	of	of	ADP
admet-942	862	33	a	a	DET
admet-942	862	34	glomerulus	glomerulus	NOUN
admet-942	862	35	chip	chip	NOUN
admet-942	862	36	.	.	PUNCT
admet-942	863	1	nat	nat	PROPN
admet-942	863	2	protoc	protoc	VERB
admet-942	863	3	176	176	NUM
admet-942	863	4	(	(	PUNCT
admet-942	863	5	2016	2016	NUM
admet-942	863	6	)	)	PUNCT
admet-942	863	7	139	139	NUM
admet-942	863	8	-	-	SYM
admet-942	863	9	148	148	NUM
admet-942	863	10	.	.	PUNCT
admet-942	863	11	https://doi.org/10.1038/s41596-018-0007-8	https://doi.org/10.1038/s41596-018-0007-8	NUM
admet-942	863	12	.	.	PUNCT
admet-942	864	1	[	[	X
admet-942	864	2	88	88	NUM
admet-942	864	3	]	]	X
admet-942	864	4	g.	g.	PROPN
admet-942	864	5	woodruff	woodruff	PROPN
admet-942	864	6	,	,	PUNCT
admet-942	864	7	s.m	s.m	PROPN
admet-942	864	8	.	.	PROPN
admet-942	864	9	reyna	reyna	PROPN
admet-942	864	10	,	,	PUNCT
admet-942	864	11	m.	m.	NOUN
admet-942	864	12	dunlap	dunlap	PROPN
admet-942	864	13	,	,	PUNCT
admet-942	864	14	r.	r.	PROPN
admet-942	864	15	van	van	PROPN
admet-942	864	16	der	der	PROPN
admet-942	864	17	kant	kant	PROPN
admet-942	864	18	,	,	PUNCT
admet-942	864	19	j.a	j.a	PROPN
admet-942	864	20	.	.	PROPN
admet-942	864	21	callender	callender	PROPN
admet-942	864	22	,	,	PUNCT
admet-942	864	23	j.e	j.e	PROPN
admet-942	864	24	.	.	PROPN
admet-942	864	25	young	young	PROPN
admet-942	864	26	,	,	PUNCT
admet-942	864	27	e.a	e.a	PROPN
admet-942	864	28	.	.	PROPN
admet-942	864	29	roberts	roberts	PROPN
admet-942	864	30	,	,	PUNCT
admet-942	864	31	l.s.b	l.s.b	ADV
admet-942	864	32	.	.	PUNCT
admet-942	865	1	goldstein	goldstein	PROPN
admet-942	865	2	.	.	PROPN
admet-942	866	1	defective	defective	ADJ
admet-942	866	2	transcytosis	transcytosis	NOUN
admet-942	866	3	of	of	ADP
admet-942	866	4	app	app	NOUN
admet-942	866	5	and	and	CCONJ
admet-942	866	6	lipoproteins	lipoprotein	NOUN
admet-942	866	7	in	in	ADP
admet-942	866	8	human	human	ADJ
admet-942	866	9	ipsc	ipsc	NOUN
admet-942	866	10	-	-	PUNCT
admet-942	866	11	derived	derive	VERB
admet-942	866	12	neurons	neuron	NOUN
admet-942	866	13	with	with	ADP
admet-942	866	14	familial	familial	ADJ
admet-942	866	15	alzheimer	alzheimer	PROPN
admet-942	866	16	’s	’s	PART
admet-942	866	17	disease	disease	NOUN
admet-942	866	18	mutations	mutation	NOUN
admet-942	866	19	.	.	PUNCT
admet-942	867	1	cell	cell	NOUN
admet-942	867	2	reports	report	VERB
admet-942	867	3	17	17	NUM
admet-942	867	4	(	(	PUNCT
admet-942	867	5	2016	2016	NUM
admet-942	867	6	)	)	PUNCT
admet-942	867	7	759	759	NUM
admet-942	867	8	-	-	SYM
admet-942	867	9	773	773	NUM
admet-942	867	10	.	.	PUNCT
admet-942	868	1	https://doi.org/10.1016/j.celrep.2016.09.034	https://doi.org/10.1016/j.celrep.2016.09.034	X
admet-942	868	2	.	.	PUNCT
admet-942	869	1	[	[	X
admet-942	869	2	89	89	NUM
admet-942	869	3	]	]	X
admet-942	869	4	y.	y.	PROPN
admet-942	869	5	wang	wang	PROPN
admet-942	869	6	,	,	PUNCT
admet-942	869	7	h.	h.	PROPN
admet-942	869	8	wang	wang	PROPN
admet-942	869	9	,	,	PUNCT
admet-942	869	10	p.	p.	PROPN
admet-942	869	11	deng	deng	PROPN
admet-942	869	12	,	,	PUNCT
admet-942	869	13	w.	w.	PROPN
admet-942	869	14	chen	chen	PROPN
admet-942	869	15	,	,	PUNCT
admet-942	869	16	y.	y.	PROPN
admet-942	869	17	guo	guo	PROPN
admet-942	869	18	,	,	PUNCT
admet-942	869	19	t.	t.	PROPN
admet-942	869	20	tao	tao	PROPN
admet-942	869	21	,	,	PUNCT
admet-942	869	22	j.	j.	PROPN
admet-942	869	23	qin	qin	PROPN
admet-942	869	24	.	.	PUNCT
admet-942	870	1	in	in	ADP
admet-942	870	2	situ	situ	ADJ
admet-942	870	3	differentiation	differentiation	NOUN
admet-942	870	4	and	and	CCONJ
admet-942	870	5	generation	generation	NOUN
admet-942	870	6	of	of	ADP
admet-942	870	7	functional	functional	ADJ
admet-942	870	8	liver	liver	NOUN
admet-942	870	9	organoids	organoid	NOUN
admet-942	870	10	from	from	ADP
admet-942	870	11	human	human	ADJ
admet-942	870	12	ipscs	ipsc	NOUN
admet-942	870	13	in	in	ADP
admet-942	870	14	a	a	DET
admet-942	870	15	3d	3d	PROPN
admet-942	870	16	perfusable	perfusable	ADJ
admet-942	870	17	chip	chip	NOUN
admet-942	870	18	system	system	NOUN
admet-942	870	19	.	.	PUNCT
admet-942	871	1	lab	lab	NOUN
admet-942	871	2	on	on	ADP
admet-942	871	3	a	a	DET
admet-942	871	4	chip	chip	NOUN
admet-942	871	5	18	18	NUM
admet-942	871	6	(	(	PUNCT
admet-942	871	7	2018	2018	NUM
admet-942	871	8	)	)	PUNCT
admet-942	871	9	3606	3606	NUM
admet-942	871	10	-	-	SYM
admet-942	871	11	3616	3616	NUM
admet-942	871	12	.	.	PUNCT
admet-942	872	1	https://doi.org/10.1039/c8lc00869h	https://doi.org/10.1039/c8lc00869h	NOUN
admet-942	872	2	.	.	PUNCT
admet-942	873	1	[	[	X
admet-942	873	2	90	90	NUM
admet-942	873	3	]	]	PUNCT
admet-942	873	4	a.	a.	NOUN
admet-942	873	5	wnorowski	wnorowski	NOUN
admet-942	873	6	,	,	PUNCT
admet-942	873	7	h.	h.	PROPN
admet-942	873	8	yang	yang	PROPN
admet-942	873	9	,	,	PUNCT
admet-942	873	10	j.c	j.c	PROPN
admet-942	873	11	.	.	PROPN
admet-942	873	12	wu	wu	PROPN
admet-942	873	13	.	.	PUNCT
admet-942	874	1	progress	progress	PROPN
admet-942	874	2	,	,	PUNCT
admet-942	874	3	obstacles	obstacle	NOUN
admet-942	874	4	,	,	PUNCT
admet-942	874	5	and	and	CCONJ
admet-942	874	6	limitations	limitation	NOUN
admet-942	874	7	in	in	ADP
admet-942	874	8	the	the	DET
admet-942	874	9	use	use	NOUN
admet-942	874	10	of	of	ADP
admet-942	874	11	stem	stem	NOUN
admet-942	874	12	cells	cell	NOUN
admet-942	874	13	in	in	ADP
admet-942	874	14	organon	organon	PROPN
admet-942	874	15	-	-	PUNCT
admet-942	874	16	a	a	DET
admet-942	874	17	-	-	PUNCT
admet-942	874	18	chip	chip	NOUN
admet-942	874	19	models	model	NOUN
admet-942	874	20	.	.	PUNCT
admet-942	875	1	advanced	advanced	ADJ
admet-942	875	2	drug	drug	NOUN
admet-942	875	3	delivery	delivery	NOUN
admet-942	875	4	reviews	review	NOUN
admet-942	875	5	140	140	NUM
admet-942	875	6	(	(	PUNCT
admet-942	875	7	2019	2019	NUM
admet-942	875	8	)	)	PUNCT
admet-942	875	9	3	3	NUM
admet-942	875	10	-	-	SYM
admet-942	875	11	11	11	NUM
admet-942	875	12	.	.	PUNCT
admet-942	876	1	https://doi.org/10.1016/j.addr.2018.06.001	https://doi.org/10.1016/j.addr.2018.06.001	PROPN
admet-942	876	2	.	.	PUNCT
admet-942	877	1	[	[	X
admet-942	877	2	91	91	NUM
admet-942	877	3	]	]	X
admet-942	877	4	r.d	r.d	PROPN
admet-942	877	5	.	.	PROPN
admet-942	877	6	kamm	kamm	PROPN
admet-942	877	7	,	,	PUNCT
admet-942	877	8	r.	r.	PROPN
admet-942	877	9	bashir	bashir	PROPN
admet-942	877	10	,	,	PUNCT
admet-942	877	11	n.	n.	PROPN
admet-942	877	12	arora	arora	PROPN
admet-942	877	13	,	,	PUNCT
admet-942	877	14	r.d	r.d	PROPN
admet-942	877	15	.	.	PROPN
admet-942	877	16	dar	dar	PROPN
admet-942	877	17	,	,	PUNCT
admet-942	877	18	m.u	m.u	PROPN
admet-942	877	19	.	.	PROPN
admet-942	877	20	gillette	gillette	PROPN
admet-942	877	21	,	,	PUNCT
admet-942	877	22	l.g	l.g	PROPN
admet-942	877	23	.	.	PROPN
admet-942	877	24	griffith	griffith	PROPN
admet-942	877	25	,	,	PUNCT
admet-942	877	26	m.l	m.l	PROPN
admet-942	877	27	.	.	PROPN
admet-942	877	28	kemp	kemp	PROPN
admet-942	877	29	,	,	PUNCT
admet-942	877	30	k.	k.	PROPN
admet-942	877	31	kinlaw	kinlaw	PROPN
admet-942	877	32	,	,	PUNCT
admet-942	877	33	m.	m.	PROPN
admet-942	877	34	levin	levin	PROPN
admet-942	877	35	,	,	PUNCT
admet-942	877	36	a.c	a.c	PROPN
admet-942	877	37	.	.	PROPN
admet-942	877	38	martin	martin	PROPN
admet-942	877	39	,	,	PUNCT
admet-942	877	40	t.c	t.c	PROPN
admet-942	877	41	.	.	PROPN
admet-942	877	42	mcdevitt	mcdevitt	PROPN
admet-942	877	43	,	,	PUNCT
admet-942	877	44	r.m	r.m	PROPN
admet-942	877	45	.	.	PROPN
admet-942	877	46	nerem	nerem	PROPN
admet-942	877	47	,	,	PUNCT
admet-942	877	48	m.j	m.j	PROPN
admet-942	877	49	.	.	PROPN
admet-942	877	50	powers	powers	PROPN
admet-942	877	51	,	,	PUNCT
admet-942	877	52	t.a	t.a	PROPN
admet-942	877	53	.	.	PROPN
admet-942	877	54	saif	saif	PROPN
admet-942	877	55	,	,	PUNCT
admet-942	877	56	j.	j.	PROPN
admet-942	877	57	sharpe	sharpe	PROPN
admet-942	877	58	,	,	PUNCT
admet-942	877	59	s.	s.	PROPN
admet-942	877	60	takayama	takayama	PROPN
admet-942	877	61	,	,	PUNCT
admet-942	877	62	s.	s.	PROPN
admet-942	877	63	takeuchi	takeuchi	PROPN
admet-942	877	64	,	,	PUNCT
admet-942	877	65	r.	r.	PROPN
admet-942	877	66	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	877	67	https://doi.org/10.1016/j.bios.2016.07.015	https://doi.org/10.1016/j.bios.2016.07.015	PRON
admet-942	877	68	https://doi.org/10.1021/acsami.0c17102	https://doi.org/10.1021/acsami.0c17102	NUM
admet-942	877	69	https://doi.org/10.1063/1.5129788	https://doi.org/10.1063/1.5129788	NOUN
admet-942	877	70	https://doi.org/10.1038/s41598-020-76062-w	https://doi.org/10.1038/s41598-020-76062-w	PROPN
admet-942	877	71	https://doi.org/10.1038/s41598-020-76062-w	https://doi.org/10.1038/s41598-020-76062-w	PROPN
admet-942	877	72	https://doi.org/10.3390/s20051531	https://doi.org/10.3390/s20051531	NUM
admet-942	877	73	https://doi.org/10.1016/j.jconrel.2014.05.004	https://doi.org/10.1016/j.jconrel.2014.05.004	PROPN
admet-942	877	74	https://doi.org/10.1242/dev.156166	https://doi.org/10.1242/dev.156166	PROPN
admet-942	878	1	https://doi.org/10.1242/dev.156166	https://doi.org/10.1242/dev.156166	PROPN
admet-942	878	2	https://doi.org/10.1038/s41596-018-0007-8	https://doi.org/10.1038/s41596-018-0007-8	NUM
admet-942	878	3	https://doi.org/10.1039/c8lc00869h	https://doi.org/10.1039/c8lc00869h	PROPN
admet-942	878	4	r.	r.	PROPN
admet-942	878	5	vargas	vargas	PROPN
admet-942	878	6	,	,	PUNCT
admet-942	878	7	a.	a.	NOUN
admet-942	878	8	egurbide	egurbide	NOUN
admet-942	878	9	-	-	PUNCT
admet-942	878	10	sifre	sifre	NOUN
admet-942	878	11	and	and	CCONJ
admet-942	878	12	l.	l.	PROPN
admet-942	878	13	medina	medina	PROPN
admet-942	878	14	admet	admet	PROPN
admet-942	878	15	&	&	CCONJ
admet-942	878	16	dmpk	dmpk	PROPN
admet-942	878	17	9(2	9(2	NUM
admet-942	878	18	)	)	PUNCT
admet-942	878	19	(	(	PUNCT
admet-942	878	20	2021	2021	NUM
admet-942	878	21	)	)	PUNCT
admet-942	878	22	111	111	NUM
admet-942	878	23	-	-	SYM
admet-942	878	24	141	141	NUM
admet-942	878	25	138	138	NUM
admet-942	878	26	weiss	weiss	NOUN
admet-942	878	27	,	,	PUNCT
admet-942	878	28	k.	k.	PROPN
admet-942	878	29	ye	ye	PROPN
admet-942	878	30	,	,	PUNCT
admet-942	878	31	h.g	h.g	PROPN
admet-942	878	32	.	.	PROPN
admet-942	878	33	yevick	yevick	PROPN
admet-942	878	34	,	,	PUNCT
admet-942	878	35	m.h	m.h	PROPN
admet-942	878	36	.	.	PROPN
admet-942	878	37	zaman	zaman	PROPN
admet-942	878	38	.	.	PUNCT
admet-942	879	1	perspective	perspective	NOUN
admet-942	879	2	:	:	PUNCT
admet-942	879	3	the	the	DET
admet-942	879	4	promise	promise	NOUN
admet-942	879	5	of	of	ADP
admet-942	879	6	multi	multi	ADJ
admet-942	879	7	-	-	ADJ
admet-942	879	8	cellular	cellular	ADJ
admet-942	879	9	engineered	engineer	VERB
admet-942	879	10	living	living	NOUN
admet-942	879	11	systems	system	NOUN
admet-942	879	12	.	.	PUNCT
admet-942	880	1	apl	apl	PROPN
admet-942	880	2	bioengineering	bioengineere	VERB
admet-942	880	3	2	2	NUM
admet-942	880	4	(	(	PUNCT
admet-942	880	5	2018	2018	NUM
admet-942	880	6	)	)	PUNCT
admet-942	880	7	040901	040901	NUM
admet-942	880	8	.	.	PUNCT
admet-942	881	1	https://doi.org/10.1063/1.5038337	https://doi.org/10.1063/1.5038337	NOUN
admet-942	881	2	.	.	PUNCT
admet-942	882	1	[	[	X
admet-942	882	2	92	92	NUM
admet-942	882	3	]	]	X
admet-942	882	4	c.p.p	c.p.p	PROPN
admet-942	882	5	.	.	PUNCT
admet-942	882	6	de	de	PROPN
admet-942	882	7	mello	mello	PROPN
admet-942	882	8	,	,	PUNCT
admet-942	882	9	j.	j.	PROPN
admet-942	882	10	rumsey	rumsey	PROPN
admet-942	882	11	,	,	PUNCT
admet-942	882	12	v.	v.	ADP
admet-942	882	13	slaughter	slaughter	PROPN
admet-942	882	14	,	,	PUNCT
admet-942	882	15	j.j	j.j	PROPN
admet-942	882	16	.	.	PROPN
admet-942	882	17	hickman	hickman	PROPN
admet-942	882	18	.	.	PUNCT
admet-942	883	1	a	a	DET
admet-942	883	2	human	human	NOUN
admet-942	883	3	-	-	PUNCT
admet-942	883	4	on	on	ADP
admet-942	883	5	-	-	PUNCT
admet-942	883	6	a	a	DET
admet-942	883	7	-	-	PUNCT
admet-942	883	8	chip	chip	NOUN
admet-942	883	9	approach	approach	NOUN
admet-942	883	10	to	to	ADP
admet-942	883	11	tackling	tackle	VERB
admet-942	883	12	rare	rare	ADJ
admet-942	883	13	diseases	disease	NOUN
admet-942	883	14	.	.	PUNCT
admet-942	884	1	drug	drug	NOUN
admet-942	884	2	discovery	discovery	PROPN
admet-942	884	3	today	today	NOUN
admet-942	884	4	24	24	NUM
admet-942	884	5	(	(	PUNCT
admet-942	884	6	2019	2019	NUM
admet-942	884	7	)	)	PUNCT
admet-942	884	8	2139	2139	NUM
admet-942	884	9	-	-	SYM
admet-942	884	10	2151	2151	NUM
admet-942	884	11	.	.	PUNCT
admet-942	885	1	https://doi.org/10.1016/j.drudis.2019.08.001	https://doi.org/10.1016/j.drudis.2019.08.001	X
admet-942	885	2	.	.	PUNCT
admet-942	886	1	[	[	X
admet-942	886	2	93	93	NUM
admet-942	886	3	]	]	PUNCT
admet-942	886	4	m.	m.	NOUN
admet-942	886	5	haddrick	haddrick	PROPN
admet-942	886	6	,	,	PUNCT
admet-942	886	7	p.b	p.b	PROPN
admet-942	886	8	.	.	PROPN
admet-942	886	9	simpson	simpson	PROPN
admet-942	886	10	.	.	PUNCT
admet-942	886	11	organ	organ	PROPN
admet-942	886	12	-	-	PUNCT
admet-942	886	13	on	on	ADP
admet-942	886	14	-	-	PUNCT
admet-942	886	15	a	a	DET
admet-942	886	16	-	-	PUNCT
admet-942	886	17	chip	chip	NOUN
admet-942	886	18	technology	technology	NOUN
admet-942	886	19	:	:	PUNCT
admet-942	886	20	turning	turn	VERB
admet-942	886	21	its	its	PRON
admet-942	886	22	potential	potential	NOUN
admet-942	886	23	for	for	ADP
admet-942	886	24	clinical	clinical	ADJ
admet-942	886	25	benefit	benefit	NOUN
admet-942	886	26	into	into	ADP
admet-942	886	27	reality	reality	NOUN
admet-942	886	28	.	.	PUNCT
admet-942	887	1	drug	drug	NOUN
admet-942	887	2	discovery	discovery	PROPN
admet-942	887	3	today	today	NOUN
admet-942	887	4	24	24	NUM
admet-942	887	5	(	(	PUNCT
admet-942	887	6	2019	2019	NUM
admet-942	887	7	)	)	PUNCT
admet-942	887	8	1217	1217	NUM
admet-942	887	9	-	-	SYM
admet-942	887	10	1223	1223	NUM
admet-942	887	11	.	.	PUNCT
admet-942	888	1	https://doi.org/10.1016/j.drudis.2019.03.011	https://doi.org/10.1016/j.drudis.2019.03.011	PROPN
admet-942	888	2	.	.	PUNCT
admet-942	889	1	[	[	X
admet-942	889	2	94	94	NUM
admet-942	889	3	]	]	X
admet-942	889	4	j.d	j.d	PROPN
admet-942	889	5	.	.	PROPN
admet-942	889	6	caplin	caplin	PROPN
admet-942	889	7	,	,	PUNCT
admet-942	889	8	n.g	n.g	PROPN
admet-942	889	9	.	.	PROPN
admet-942	889	10	granados	granados	PROPN
admet-942	889	11	,	,	PUNCT
admet-942	889	12	m.r	m.r	PROPN
admet-942	889	13	.	.	PROPN
admet-942	889	14	james	james	PROPN
admet-942	889	15	,	,	PUNCT
admet-942	889	16	r.	r.	PROPN
admet-942	889	17	montazami	montazami	PROPN
admet-942	889	18	,	,	PUNCT
admet-942	889	19	n.	n.	PROPN
admet-942	889	20	hashemi	hashemi	PROPN
admet-942	889	21	.	.	PUNCT
admet-942	890	1	microfluidic	microfluidic	ADJ
admet-942	890	2	organ	organ	NOUN
admet-942	890	3	-	-	PUNCT
admet-942	890	4	on	on	ADP
admet-942	890	5	-	-	PUNCT
admet-942	890	6	a	a	DET
admet-942	890	7	-	-	PUNCT
admet-942	890	8	chip	chip	NOUN
admet-942	890	9	technology	technology	NOUN
admet-942	890	10	for	for	ADP
admet-942	890	11	advancement	advancement	NOUN
admet-942	890	12	of	of	ADP
admet-942	890	13	drug	drug	NOUN
admet-942	890	14	development	development	NOUN
admet-942	890	15	and	and	CCONJ
admet-942	890	16	toxicology	toxicology	NOUN
admet-942	890	17	.	.	PUNCT
admet-942	891	1	advanced	advanced	ADJ
admet-942	891	2	healthcare	healthcare	NOUN
admet-942	891	3	materials	material	NOUN
admet-942	891	4	4	4	NUM
admet-942	891	5	(	(	PUNCT
admet-942	891	6	2015	2015	NUM
admet-942	891	7	)	)	PUNCT
admet-942	891	8	1426	1426	NUM
admet-942	891	9	-	-	SYM
admet-942	891	10	1450	1450	NUM
admet-942	891	11	.	.	PUNCT
admet-942	892	1	https://doi.org/10.1002/adhm.201500040	https://doi.org/10.1002/adhm.201500040	X
admet-942	892	2	.	.	PUNCT
admet-942	893	1	[	[	X
admet-942	893	2	95	95	NUM
admet-942	893	3	]	]	X
admet-942	893	4	a.k	a.k	PROPN
admet-942	893	5	.	.	PROPN
admet-942	893	6	schroer	schroer	PROPN
admet-942	893	7	,	,	PUNCT
admet-942	893	8	m.s	m.s	PROPN
admet-942	893	9	.	.	PROPN
admet-942	893	10	shotwell	shotwell	PROPN
admet-942	893	11	,	,	PUNCT
admet-942	893	12	v.y	v.y	PROPN
admet-942	893	13	.	.	PROPN
admet-942	893	14	sidorov	sidorov	PROPN
admet-942	893	15	,	,	PUNCT
admet-942	893	16	j.p	j.p	PROPN
admet-942	893	17	.	.	PROPN
admet-942	893	18	wikswo	wikswo	PROPN
admet-942	893	19	,	,	PUNCT
admet-942	893	20	w.d	w.d	PROPN
admet-942	893	21	.	.	PUNCT
admet-942	893	22	merryman	merryman	NOUN
admet-942	893	23	.	.	PUNCT
admet-942	894	1	i	i	PRON
admet-942	894	2	-	-	PUNCT
admet-942	894	3	wire	wire	NOUN
admet-942	894	4	heart	heart	NOUN
admet-942	894	5	-	-	PUNCT
admet-942	894	6	on	on	ADP
admet-942	894	7	-	-	PUNCT
admet-942	894	8	a	a	DET
admet-942	894	9	-	-	PUNCT
admet-942	894	10	chip	chip	NOUN
admet-942	894	11	ii	ii	NOUN
admet-942	894	12	:	:	PUNCT
admet-942	894	13	biomechanical	biomechanical	ADJ
admet-942	894	14	analysis	analysis	NOUN
admet-942	894	15	of	of	ADP
admet-942	894	16	contractile	contractile	NOUN
admet-942	894	17	,	,	PUNCT
admet-942	894	18	three	three	NUM
admet-942	894	19	-	-	PUNCT
admet-942	894	20	dimensional	dimensional	ADJ
admet-942	894	21	cardiomyocyte	cardiomyocyte	NOUN
admet-942	894	22	tissue	tissue	NOUN
admet-942	894	23	constructs	construct	VERB
admet-942	894	24	.	.	PUNCT
admet-942	895	1	acta	acta	PROPN
admet-942	895	2	biomaterialia	biomaterialia	PROPN
admet-942	895	3	48	48	NUM
admet-942	895	4	(	(	PUNCT
admet-942	895	5	2017	2017	NUM
admet-942	895	6	)	)	PUNCT
admet-942	895	7	79	79	NUM
admet-942	895	8	-	-	SYM
admet-942	895	9	87	87	NUM
admet-942	895	10	.	.	PUNCT
admet-942	896	1	https://doi.org/10.1016/j.actbio.2016.11.010	https://doi.org/10.1016/j.actbio.2016.11.010	NUM
admet-942	896	2	.	.	PUNCT
admet-942	897	1	[	[	X
admet-942	897	2	96	96	NUM
admet-942	897	3	]	]	X
admet-942	897	4	p.	p.	NOUN
admet-942	897	5	loskill	loskill	PROPN
admet-942	897	6	,	,	PUNCT
admet-942	897	7	a.	a.	PROPN
admet-942	897	8	mathur	mathur	PROPN
admet-942	897	9	,	,	PUNCT
admet-942	897	10	b.r	b.r	PROPN
admet-942	897	11	.	.	PROPN
admet-942	897	12	conklin	conklin	PROPN
admet-942	897	13	,	,	PUNCT
admet-942	897	14	a.	a.	PROPN
admet-942	897	15	stahl	stahl	PROPN
admet-942	897	16	,	,	PUNCT
admet-942	897	17	l.p	l.p	PROPN
admet-942	897	18	.	.	PROPN
admet-942	897	19	lee	lee	PROPN
admet-942	897	20	,	,	PUNCT
admet-942	897	21	k.e	k.e	PROPN
admet-942	897	22	.	.	PROPN
admet-942	897	23	healy	healy	PROPN
admet-942	897	24	.	.	PUNCT
admet-942	898	1	organs	organ	NOUN
admet-942	898	2	-	-	PUNCT
admet-942	898	3	on	on	ADP
admet-942	898	4	-	-	PUNCT
admet-942	898	5	a	a	DET
admet-942	898	6	-	-	PUNCT
admet-942	898	7	chip	chip	NOUN
admet-942	898	8	–	–	PUNCT
admet-942	898	9	microphysiological	microphysiological	ADJ
admet-942	898	10	platforms	platform	NOUN
admet-942	898	11	as	as	ADP
admet-942	898	12	in	in	ADP
admet-942	898	13	vitro	vitro	X
admet-942	898	14	models	model	NOUN
admet-942	898	15	of	of	ADP
admet-942	898	16	cardiac	cardiac	ADJ
admet-942	898	17	and	and	CCONJ
admet-942	898	18	adipose	adipose	ADJ
admet-942	898	19	tissue	tissue	NOUN
admet-942	898	20	.	.	PUNCT
admet-942	899	1	toxicology	toxicology	NOUN
admet-942	899	2	letters	letter	NOUN
admet-942	899	3	258	258	NUM
admet-942	899	4	(	(	PUNCT
admet-942	899	5	2016	2016	NUM
admet-942	899	6	)	)	PUNCT
admet-942	899	7	s153	s153	NUM
admet-942	899	8	.	.	PUNCT
admet-942	900	1	https://doi.org/10.1016/j.toxlet.2016.06.1586	https://doi.org/10.1016/j.toxlet.2016.06.1586	PROPN
admet-942	900	2	.	.	PUNCT
admet-942	901	1	[	[	X
admet-942	901	2	97	97	NUM
admet-942	901	3	]	]	X
admet-942	901	4	l.	l.	PROPN
admet-942	901	5	yin	yin	PROPN
admet-942	901	6	,	,	PUNCT
admet-942	901	7	g.	g.	PROPN
admet-942	901	8	du	du	PROPN
admet-942	901	9	,	,	PUNCT
admet-942	901	10	b.	b.	PROPN
admet-942	901	11	zhang	zhang	PROPN
admet-942	901	12	,	,	PUNCT
admet-942	901	13	h.	h.	PROPN
admet-942	901	14	zhang	zhang	PROPN
admet-942	901	15	,	,	PUNCT
admet-942	901	16	r.	r.	PROPN
admet-942	901	17	yin	yin	PROPN
admet-942	901	18	,	,	PUNCT
admet-942	901	19	w.	w.	PROPN
admet-942	901	20	zhang	zhang	PROPN
admet-942	901	21	,	,	PUNCT
admet-942	901	22	s.m	s.m	PROPN
admet-942	901	23	.	.	PROPN
admet-942	901	24	yang	yang	PROPN
admet-942	901	25	.	.	PUNCT
admet-942	902	1	efficient	efficient	ADJ
admet-942	902	2	drug	drug	NOUN
admet-942	902	3	screening	screening	NOUN
admet-942	902	4	and	and	CCONJ
admet-942	902	5	nephrotoxicity	nephrotoxicity	NOUN
admet-942	902	6	assessment	assessment	NOUN
admet-942	902	7	on	on	ADP
admet-942	902	8	co	co	ADJ
admet-942	902	9	-	-	NOUN
admet-942	902	10	culture	culture	ADJ
admet-942	902	11	microfluidic	microfluidic	ADJ
admet-942	902	12	kidney	kidney	NOUN
admet-942	902	13	chip	chip	NOUN
admet-942	902	14	.	.	PUNCT
admet-942	903	1	scientific	scientific	ADJ
admet-942	903	2	reports	report	NOUN
admet-942	903	3	10	10	NUM
admet-942	903	4	(	(	PUNCT
admet-942	903	5	2020	2020	NUM
admet-942	903	6	)	)	PUNCT
admet-942	903	7	1	1	NUM
admet-942	903	8	-	-	SYM
admet-942	903	9	11	11	NUM
admet-942	903	10	.	.	PUNCT
admet-942	904	1	https://doi.org/10.1038/s41598-020-63096-3	https://doi.org/10.1038/s41598-020-63096-3	X
admet-942	904	2	.	.	PUNCT
admet-942	905	1	[	[	X
admet-942	905	2	98	98	NUM
admet-942	905	3	]	]	X
admet-942	905	4	k.-j	k.-j	PROPN
admet-942	905	5	.	.	PUNCT
admet-942	905	6	jang	jang	PROPN
admet-942	905	7	,	,	PUNCT
admet-942	905	8	a.p	a.p	PROPN
admet-942	905	9	.	.	PROPN
admet-942	905	10	mehr	mehr	PROPN
admet-942	905	11	,	,	PUNCT
admet-942	905	12	g.a	g.a	PROPN
admet-942	905	13	.	.	PROPN
admet-942	905	14	hamilton	hamilton	PROPN
admet-942	905	15	,	,	PUNCT
admet-942	905	16	l.a	l.a	PROPN
admet-942	905	17	.	.	PROPN
admet-942	905	18	mcpartlin	mcpartlin	PROPN
admet-942	905	19	,	,	PUNCT
admet-942	905	20	s.	s.	PROPN
admet-942	905	21	chung	chung	PROPN
admet-942	905	22	,	,	PUNCT
admet-942	905	23	k.-y	k.-y	NOUN
admet-942	905	24	.	.	PUNCT
admet-942	906	1	suh	suh	PROPN
admet-942	906	2	,	,	PUNCT
admet-942	906	3	d.e	d.e	PROPN
admet-942	906	4	.	.	PROPN
admet-942	906	5	ingber	ingber	PROPN
admet-942	906	6	.	.	PUNCT
admet-942	907	1	human	human	ADJ
admet-942	907	2	kidney	kidney	PROPN
admet-942	907	3	proximal	proximal	ADJ
admet-942	907	4	tubule	tubule	NOUN
admet-942	907	5	-	-	PUNCT
admet-942	907	6	on	on	ADP
admet-942	907	7	-	-	PUNCT
admet-942	907	8	a	a	DET
admet-942	907	9	-	-	PUNCT
admet-942	907	10	chip	chip	NOUN
admet-942	907	11	for	for	ADP
admet-942	907	12	drug	drug	NOUN
admet-942	907	13	transport	transport	NOUN
admet-942	907	14	and	and	CCONJ
admet-942	907	15	nephrotoxicity	nephrotoxicity	NOUN
admet-942	907	16	assessment	assessment	NOUN
admet-942	907	17	.	.	PUNCT
admet-942	908	1	integrative	integrative	ADJ
admet-942	908	2	biology	biology	NOUN
admet-942	908	3	5	5	NUM
admet-942	908	4	(	(	PUNCT
admet-942	908	5	2013	2013	NUM
admet-942	908	6	)	)	PUNCT
admet-942	908	7	1119	1119	NUM
admet-942	908	8	-	-	SYM
admet-942	908	9	1129	1129	NUM
admet-942	908	10	.	.	PUNCT
admet-942	909	1	https://doi.org/10.1039/c3ib40049b	https://doi.org/10.1039/c3ib40049b	NOUN
admet-942	909	2	.	.	PUNCT
admet-942	910	1	[	[	X
admet-942	910	2	99	99	NUM
admet-942	910	3	]	]	X
admet-942	910	4	a.o	a.o	PROPN
admet-942	910	5	.	.	PROPN
admet-942	910	6	stucki	stucki	PROPN
admet-942	910	7	,	,	PUNCT
admet-942	910	8	j.d	j.d	PROPN
admet-942	910	9	.	.	PROPN
admet-942	910	10	stucki	stucki	PROPN
admet-942	910	11	,	,	PUNCT
admet-942	910	12	s.r.r	s.r.r	PROPN
admet-942	910	13	.	.	PROPN
admet-942	910	14	hall	hall	PROPN
admet-942	910	15	,	,	PUNCT
admet-942	910	16	m.	m.	NOUN
admet-942	910	17	felder	felder	PROPN
admet-942	910	18	,	,	PUNCT
admet-942	910	19	y.	y.	PROPN
admet-942	910	20	mermoud	mermoud	PROPN
admet-942	910	21	,	,	PUNCT
admet-942	910	22	r.a	r.a	PROPN
admet-942	910	23	.	.	PROPN
admet-942	910	24	schmid	schmid	PROPN
admet-942	910	25	,	,	PUNCT
admet-942	910	26	t.	t.	PROPN
admet-942	910	27	geiser	geiser	PROPN
admet-942	910	28	,	,	PUNCT
admet-942	910	29	o.t	o.t	PROPN
admet-942	910	30	.	.	PROPN
admet-942	910	31	guenat	guenat	PROPN
admet-942	910	32	.	.	PUNCT
admet-942	911	1	a	a	DET
admet-942	911	2	lung	lung	NOUN
admet-942	911	3	-	-	PUNCT
admet-942	911	4	on	on	ADP
admet-942	911	5	-	-	PUNCT
admet-942	911	6	a	a	DET
admet-942	911	7	-	-	PUNCT
admet-942	911	8	chip	chip	NOUN
admet-942	911	9	array	array	NOUN
admet-942	911	10	with	with	ADP
admet-942	911	11	an	an	DET
admet-942	911	12	integrated	integrate	VERB
admet-942	911	13	bio	bio	ADJ
admet-942	911	14	-	-	PUNCT
admet-942	911	15	inspired	inspire	VERB
admet-942	911	16	respiration	respiration	NOUN
admet-942	911	17	mechanism	mechanism	NOUN
admet-942	911	18	.	.	PUNCT
admet-942	912	1	lab	lab	NOUN
admet-942	912	2	on	on	ADP
admet-942	912	3	a	a	DET
admet-942	912	4	chip	chip	NOUN
admet-942	912	5	15	15	NUM
admet-942	912	6	(	(	PUNCT
admet-942	912	7	2015	2015	NUM
admet-942	912	8	)	)	PUNCT
admet-942	912	9	1302	1302	NUM
admet-942	912	10	-	-	SYM
admet-942	912	11	1310	1310	NUM
admet-942	912	12	.	.	PUNCT
admet-942	913	1	https://doi.org/10.1039/c4lc01252f	https://doi.org/10.1039/c4lc01252f	PROPN
admet-942	913	2	.	.	PUNCT
admet-942	914	1	[	[	X
admet-942	914	2	100	100	NUM
admet-942	914	3	]	]	PUNCT
admet-942	914	4	m.	m.	NOUN
admet-942	914	5	felder	felder	PROPN
admet-942	914	6	,	,	PUNCT
admet-942	914	7	b.	b.	PROPN
admet-942	914	8	trueeb	trueeb	PROPN
admet-942	914	9	,	,	PUNCT
admet-942	914	10	a.o	a.o	PROPN
admet-942	914	11	.	.	PROPN
admet-942	914	12	stucki	stucki	PROPN
admet-942	914	13	,	,	PUNCT
admet-942	914	14	s.	s.	PROPN
admet-942	914	15	borcard	borcard	PROPN
admet-942	914	16	,	,	PUNCT
admet-942	914	17	j.d	j.d	PROPN
admet-942	914	18	.	.	PROPN
admet-942	914	19	stucki	stucki	PROPN
admet-942	914	20	,	,	PUNCT
admet-942	914	21	b.	b.	PROPN
admet-942	914	22	schnyder	schnyder	PROPN
admet-942	914	23	,	,	PUNCT
admet-942	914	24	t.	t.	PROPN
admet-942	914	25	geiser	geiser	PROPN
admet-942	914	26	,	,	PUNCT
admet-942	914	27	o.t	o.t	PROPN
admet-942	914	28	.	.	PROPN
admet-942	914	29	guenat	guenat	PROPN
admet-942	914	30	.	.	PUNCT
admet-942	915	1	impaired	impair	VERB
admet-942	915	2	wound	wound	NOUN
admet-942	915	3	healing	healing	NOUN
admet-942	915	4	of	of	ADP
admet-942	915	5	alveolar	alveolar	ADJ
admet-942	915	6	lung	lung	NOUN
admet-942	915	7	epithelial	epithelial	ADJ
admet-942	915	8	cells	cell	NOUN
admet-942	915	9	in	in	ADP
admet-942	915	10	a	a	DET
admet-942	915	11	breathing	breathe	VERB
admet-942	915	12	lung	lung	NOUN
admet-942	915	13	-	-	PUNCT
admet-942	915	14	on	on	ADP
admet-942	915	15	-	-	PUNCT
admet-942	915	16	a	a	DET
admet-942	915	17	-	-	PUNCT
admet-942	915	18	chip	chip	NOUN
admet-942	915	19	.	.	PUNCT
admet-942	916	1	frontiers	frontier	NOUN
admet-942	916	2	in	in	ADP
admet-942	916	3	bioengineering	bioengineering	NOUN
admet-942	916	4	and	and	CCONJ
admet-942	916	5	biotechnology	biotechnology	NOUN
admet-942	916	6	7	7	NUM
admet-942	916	7	(	(	PUNCT
admet-942	916	8	2019	2019	NUM
admet-942	916	9	)	)	PUNCT
admet-942	916	10	3	3	NUM
admet-942	916	11	.	.	PUNCT
admet-942	917	1	https://doi.org/10.3389/fbioe.2019.00003	https://doi.org/10.3389/fbioe.2019.00003	NOUN
admet-942	917	2	.	.	PUNCT
admet-942	918	1	[	[	X
admet-942	918	2	101	101	NUM
admet-942	918	3	]	]	PUNCT
admet-942	918	4	m.a.u	m.a.u	NOUN
admet-942	918	5	.	.	PUNCT
admet-942	919	1	khalid	khalid	PROPN
admet-942	919	2	,	,	PUNCT
admet-942	919	3	y.s	y.s	PROPN
admet-942	919	4	.	.	PROPN
admet-942	919	5	kim	kim	PROPN
admet-942	919	6	,	,	PUNCT
admet-942	919	7	m.	m.	PROPN
admet-942	919	8	ali	ali	PROPN
admet-942	919	9	,	,	PUNCT
admet-942	919	10	b.g	b.g	PROPN
admet-942	919	11	.	.	PROPN
admet-942	919	12	lee	lee	PROPN
admet-942	919	13	,	,	PUNCT
admet-942	919	14	y.j	y.j	PROPN
admet-942	919	15	.	.	PUNCT
admet-942	919	16	cho	cho	PROPN
admet-942	919	17	,	,	PUNCT
admet-942	919	18	k.h	k.h	PROPN
admet-942	919	19	.	.	PROPN
admet-942	919	20	choi	choi	PROPN
admet-942	919	21	.	.	PUNCT
admet-942	920	1	a	a	DET
admet-942	920	2	lung	lung	NOUN
admet-942	920	3	cancer	cancer	NOUN
admet-942	920	4	-	-	PUNCT
admet-942	920	5	on	on	ADP
admet-942	920	6	-	-	PUNCT
admet-942	920	7	chip	chip	NOUN
admet-942	920	8	platform	platform	NOUN
admet-942	920	9	with	with	ADP
admet-942	920	10	integrated	integrated	ADJ
admet-942	920	11	biosensors	biosensor	NOUN
admet-942	920	12	for	for	ADP
admet-942	920	13	physiological	physiological	ADJ
admet-942	920	14	monitoring	monitoring	NOUN
admet-942	920	15	and	and	CCONJ
admet-942	920	16	toxicity	toxicity	NOUN
admet-942	920	17	assessment	assessment	NOUN
admet-942	920	18	.	.	PUNCT
admet-942	921	1	biochemical	biochemical	ADJ
admet-942	921	2	engineering	engineering	NOUN
admet-942	921	3	journal	journal	PROPN
admet-942	921	4	155	155	NUM
admet-942	921	5	(	(	PUNCT
admet-942	921	6	2020	2020	NUM
admet-942	921	7	)	)	PUNCT
admet-942	921	8	107469	107469	NUM
admet-942	921	9	.	.	PUNCT
admet-942	922	1	https://doi.org/10.1016/j.bej.2019.107469	https://doi.org/10.1016/j.bej.2019.107469	PUNCT
admet-942	922	2	.	.	PUNCT
admet-942	923	1	[	[	X
admet-942	923	2	102	102	NUM
admet-942	923	3	]	]	X
admet-942	923	4	j.	j.	PROPN
admet-942	923	5	rogal	rogal	PROPN
admet-942	923	6	,	,	PUNCT
admet-942	923	7	a.	a.	NOUN
admet-942	923	8	zbinden	zbinden	PROPN
admet-942	923	9	,	,	PUNCT
admet-942	923	10	k.	k.	PROPN
admet-942	923	11	schenke	schenke	PROPN
admet-942	923	12	-	-	PUNCT
admet-942	923	13	layland	layland	NOUN
admet-942	923	14	,	,	PUNCT
admet-942	923	15	p.	p.	PROPN
admet-942	923	16	loskill	loskill	PROPN
admet-942	923	17	.	.	PUNCT
admet-942	923	18	stem	stem	NOUN
admet-942	923	19	-	-	PUNCT
admet-942	923	20	cell	cell	NOUN
admet-942	923	21	based	base	VERB
admet-942	923	22	organ	organ	NOUN
admet-942	923	23	-	-	PUNCT
admet-942	923	24	on	on	ADP
admet-942	923	25	-	-	PUNCT
admet-942	923	26	a	a	DET
admet-942	923	27	-	-	PUNCT
admet-942	923	28	chip	chip	NOUN
admet-942	923	29	models	model	NOUN
admet-942	923	30	for	for	ADP
admet-942	923	31	diabetes	diabetes	NOUN
admet-942	923	32	research	research	NOUN
admet-942	923	33	.	.	PUNCT
admet-942	924	1	advanced	advanced	ADJ
admet-942	924	2	drug	drug	NOUN
admet-942	924	3	delivery	delivery	NOUN
admet-942	924	4	reviews	review	NOUN
admet-942	924	5	140	140	NUM
admet-942	924	6	(	(	PUNCT
admet-942	924	7	2019	2019	NUM
admet-942	924	8	)	)	PUNCT
admet-942	924	9	101	101	NUM
admet-942	924	10	-	-	SYM
admet-942	924	11	128	128	NUM
admet-942	924	12	.	.	PUNCT
admet-942	925	1	https://doi.org/10.1016/j.addr.2018.10.010	https://doi.org/10.1016/j.addr.2018.10.010	PROPN
admet-942	925	2	.	.	PUNCT
admet-942	926	1	[	[	X
admet-942	926	2	103	103	NUM
admet-942	926	3	]	]	PUNCT
admet-942	926	4	a.	a.	NOUN
admet-942	926	5	bein	bein	PROPN
admet-942	926	6	,	,	PUNCT
admet-942	926	7	w.	w.	PROPN
admet-942	926	8	shin	shin	PROPN
admet-942	926	9	,	,	PUNCT
admet-942	926	10	s.	s.	PROPN
admet-942	926	11	jalili	jalili	PROPN
admet-942	926	12	-	-	PUNCT
admet-942	926	13	firoozinezhad	firoozinezhad	VERB
admet-942	926	14	,	,	PUNCT
admet-942	926	15	m.h	m.h	PROPN
admet-942	926	16	.	.	PROPN
admet-942	926	17	park	park	PROPN
admet-942	926	18	,	,	PUNCT
admet-942	926	19	a.	a.	PROPN
admet-942	926	20	sontheimer	sontheimer	PROPN
admet-942	926	21	-	-	PUNCT
admet-942	926	22	phelps	phelps	PROPN
admet-942	926	23	,	,	PUNCT
admet-942	926	24	a.	a.	PROPN
admet-942	926	25	tovaglieri	tovaglieri	PROPN
admet-942	926	26	,	,	PUNCT
admet-942	926	27	a.	a.	NOUN
admet-942	926	28	chalkiadaki	chalkiadaki	PROPN
admet-942	926	29	,	,	PUNCT
admet-942	926	30	h.j	h.j	PROPN
admet-942	926	31	.	.	PROPN
admet-942	926	32	kim	kim	PROPN
admet-942	926	33	,	,	PUNCT
admet-942	926	34	d.e	d.e	PROPN
admet-942	926	35	.	.	PROPN
admet-942	926	36	ingber	ingber	PROPN
admet-942	926	37	.	.	PUNCT
admet-942	927	1	microfluidic	microfluidic	ADJ
admet-942	927	2	organ	organ	NOUN
admet-942	927	3	-	-	PUNCT
admet-942	927	4	on	on	ADP
admet-942	927	5	-	-	PUNCT
admet-942	927	6	a	a	DET
admet-942	927	7	-	-	PUNCT
admet-942	927	8	chip	chip	NOUN
admet-942	927	9	models	model	NOUN
admet-942	927	10	of	of	ADP
admet-942	927	11	human	human	ADJ
admet-942	927	12	intestine	intestine	NOUN
admet-942	927	13	.	.	PUNCT
admet-942	928	1	cmgh	cmgh	NOUN
admet-942	928	2	5	5	NUM
admet-942	928	3	(	(	PUNCT
admet-942	928	4	2018	2018	NUM
admet-942	928	5	)	)	PUNCT
admet-942	928	6	659668	659668	NUM
admet-942	928	7	.	.	PUNCT
admet-942	929	1	https://doi.org/10.1016/j.jcmgh.2017.12.010	https://doi.org/10.1016/j.jcmgh.2017.12.010	NUM
admet-942	929	2	.	.	PUNCT
admet-942	930	1	[	[	X
admet-942	930	2	104	104	X
admet-942	930	3	]	]	X
admet-942	930	4	c.a	c.a	PROPN
admet-942	930	5	.	.	PROPN
admet-942	930	6	richmond	richmond	PROPN
admet-942	930	7	,	,	PUNCT
admet-942	930	8	d.t	d.t	PROPN
admet-942	930	9	.	.	PROPN
admet-942	930	10	breault	breault	PROPN
admet-942	930	11	.	.	PUNCT
admet-942	930	12	move	move	VERB
admet-942	930	13	over	over	ADP
admet-942	930	14	caco-2	caco-2	NUM
admet-942	930	15	cells	cell	NOUN
admet-942	930	16	:	:	PUNCT
admet-942	930	17	human	human	NOUN
admet-942	930	18	-	-	PUNCT
admet-942	930	19	induced	induce	VERB
admet-942	930	20	organoids	organoid	NOUN
admet-942	930	21	meet	meet	VERB
admet-942	930	22	gut	gut	NOUN
admet-942	930	23	-	-	PUNCT
admet-942	930	24	on	on	ADP
admet-942	930	25	-	-	PUNCT
admet-942	930	26	achip	achip	NOUN
admet-942	930	27	.	.	PUNCT
admet-942	931	1	cmgh	cmgh	NOUN
admet-942	931	2	5	5	NUM
admet-942	931	3	(	(	PUNCT
admet-942	931	4	2018	2018	NUM
admet-942	931	5	)	)	PUNCT
admet-942	931	6	634	634	NUM
admet-942	931	7	-	-	SYM
admet-942	931	8	635	635	NUM
admet-942	931	9	.	.	PUNCT
admet-942	932	1	https://doi.org/10.1016/j.jcmgh.2018.01.016	https://doi.org/10.1016/j.jcmgh.2018.01.016	PROPN
admet-942	932	2	.	.	PUNCT
admet-942	933	1	[	[	X
admet-942	933	2	105	105	NUM
admet-942	933	3	]	]	X
admet-942	933	4	k.m	k.m	PROPN
admet-942	933	5	.	.	PROPN
admet-942	933	6	seiler	seiler	PROPN
admet-942	933	7	,	,	PUNCT
admet-942	933	8	a.	a.	NOUN
admet-942	933	9	bajinting	bajinting	PROPN
admet-942	933	10	,	,	PUNCT
admet-942	933	11	d.m	d.m	PROPN
admet-942	933	12	.	.	PUNCT
admet-942	934	1	alvarado	alvarado	PROPN
admet-942	934	2	,	,	PUNCT
admet-942	934	3	m.a	m.a	PROPN
admet-942	934	4	.	.	PROPN
admet-942	934	5	traore	traore	PROPN
admet-942	934	6	,	,	PUNCT
admet-942	934	7	m.m	m.m	PROPN
admet-942	934	8	.	.	PROPN
admet-942	934	9	binkley	binkley	PROPN
admet-942	934	10	,	,	PUNCT
admet-942	934	11	w.h	w.h	PROPN
admet-942	934	12	.	.	PROPN
admet-942	934	13	goo	goo	PROPN
admet-942	934	14	,	,	PUNCT
admet-942	934	15	w.e	w.e	PROPN
admet-942	934	16	.	.	PROPN
admet-942	934	17	lanik	lanik	PROPN
admet-942	934	18	,	,	PUNCT
admet-942	934	19	j.	j.	PROPN
admet-942	934	20	ou	ou	PROPN
admet-942	934	21	,	,	PUNCT
admet-942	934	22	u.	u.	PROPN
admet-942	934	23	ismail	ismail	PROPN
admet-942	934	24	,	,	PUNCT
admet-942	934	25	m.	m.	NOUN
admet-942	934	26	iticovici	iticovici	PROPN
admet-942	934	27	,	,	PUNCT
admet-942	934	28	c.r	c.r	PROPN
admet-942	934	29	.	.	PROPN
admet-942	934	30	king	king	PROPN
admet-942	934	31	,	,	PUNCT
admet-942	934	32	k.l	k.l	PROPN
admet-942	934	33	.	.	PROPN
admet-942	934	34	vandussen	vandussen	PROPN
admet-942	934	35	,	,	PUNCT
admet-942	934	36	e.a	e.a	PROPN
admet-942	934	37	.	.	PROPN
admet-942	934	38	swietlicki	swietlicki	PROPN
admet-942	934	39	,	,	PUNCT
admet-942	934	40	v.	v.	PROPN
admet-942	934	41	gazit	gazit	PROPN
admet-942	934	42	,	,	PUNCT
admet-942	934	43	j.	j.	PROPN
admet-942	934	44	guo	guo	PROPN
admet-942	934	45	,	,	PUNCT
admet-942	934	46	c.j	c.j	PROPN
admet-942	934	47	.	.	PROPN
admet-942	934	48	luke	luke	PROPN
admet-942	934	49	,	,	PUNCT
admet-942	934	50	t.	t.	NOUN
admet-942	934	51	stappenbeck	stappenbeck	NOUN
admet-942	934	52	,	,	PUNCT
admet-942	934	53	m.a	m.a	PROPN
admet-942	934	54	.	.	PROPN
admet-942	934	55	ciorba	ciorba	PROPN
admet-942	934	56	,	,	PUNCT
admet-942	934	57	s.c	s.c	PROPN
admet-942	934	58	.	.	PROPN
admet-942	934	59	george	george	PROPN
admet-942	934	60	,	,	PUNCT
admet-942	934	61	j.m	j.m	PROPN
admet-942	934	62	.	.	PROPN
admet-942	934	63	meacham	meacham	PROPN
admet-942	934	64	,	,	PUNCT
admet-942	934	65	d.c	d.c	PROPN
admet-942	934	66	.	.	PUNCT
admet-942	934	67	rubin	rubin	PROPN
admet-942	934	68	,	,	PUNCT
admet-942	934	69	m.	m.	PROPN
admet-942	934	70	good	good	PROPN
admet-942	934	71	,	,	PUNCT
admet-942	934	72	b.w	b.w	PROPN
admet-942	934	73	.	.	PROPN
admet-942	934	74	warner	warner	PROPN
admet-942	934	75	.	.	PUNCT
admet-942	935	1	patientderived	patientderive	VERB
admet-942	935	2	small	small	ADJ
admet-942	935	3	intestinal	intestinal	ADJ
admet-942	935	4	myofibroblasts	myofibroblast	NOUN
admet-942	935	5	direct	direct	ADJ
admet-942	935	6	perfused	perfuse	VERB
admet-942	935	7	,	,	PUNCT
admet-942	935	8	physiologically	physiologically	ADV
admet-942	935	9	responsive	responsive	ADJ
admet-942	935	10	capillary	capillary	ADJ
admet-942	935	11	development	development	NOUN
admet-942	935	12	in	in	ADP
admet-942	935	13	a	a	DET
admet-942	935	14	microfluidic	microfluidic	ADJ
admet-942	935	15	gut	gut	NOUN
admet-942	935	16	-	-	PUNCT
admet-942	935	17	on	on	ADP
admet-942	935	18	-	-	PUNCT
admet-942	935	19	a	a	DET
admet-942	935	20	-	-	PUNCT
admet-942	935	21	chip	chip	NOUN
admet-942	935	22	model	model	NOUN
admet-942	935	23	.	.	PUNCT
admet-942	936	1	scientific	scientific	ADJ
admet-942	936	2	reports	report	NOUN
admet-942	936	3	10	10	NUM
admet-942	936	4	(	(	PUNCT
admet-942	936	5	2020	2020	NUM
admet-942	936	6	)	)	PUNCT
admet-942	936	7	.	.	PUNCT
admet-942	937	1	https://doi.org/10.1038/s41598-020-60672-5	https://doi.org/10.1038/s41598-020-60672-5	NOUN
admet-942	937	2	.	.	PUNCT
admet-942	938	1	[	[	X
admet-942	938	2	106	106	NUM
admet-942	938	3	]	]	X
admet-942	938	4	m.	m.	NOUN
admet-942	938	5	kasendra	kasendra	PROPN
admet-942	938	6	,	,	PUNCT
admet-942	938	7	a.	a.	PROPN
admet-942	938	8	tovaglieri	tovaglieri	PROPN
admet-942	938	9	,	,	PUNCT
admet-942	938	10	a.	a.	PROPN
admet-942	938	11	sontheimer	sontheimer	PROPN
admet-942	938	12	-	-	PUNCT
admet-942	938	13	phelps	phelps	PROPN
admet-942	938	14	,	,	PUNCT
admet-942	938	15	s.	s.	PROPN
admet-942	938	16	jalili	jalili	PROPN
admet-942	938	17	-	-	PUNCT
admet-942	938	18	firoozinezhad	firoozinezhad	PROPN
admet-942	938	19	,	,	PUNCT
admet-942	938	20	a.	a.	NOUN
admet-942	938	21	bein	bein	PROPN
admet-942	938	22	,	,	PUNCT
admet-942	938	23	a.	a.	NOUN
admet-942	938	24	chalkiadaki	chalkiadaki	PROPN
admet-942	938	25	,	,	PUNCT
admet-942	938	26	w.	w.	PROPN
admet-942	938	27	scholl	scholl	PROPN
admet-942	938	28	,	,	PUNCT
admet-942	938	29	c.	c.	PROPN
admet-942	938	30	zhang	zhang	PROPN
admet-942	938	31	,	,	PUNCT
admet-942	938	32	h.	h.	PROPN
admet-942	938	33	rickner	rickner	PROPN
admet-942	938	34	,	,	PUNCT
admet-942	938	35	c.a	c.a	PROPN
admet-942	938	36	.	.	PROPN
admet-942	938	37	richmond	richmond	PROPN
admet-942	938	38	,	,	PUNCT
admet-942	938	39	h.	h.	PROPN
admet-942	938	40	li	li	PROPN
admet-942	938	41	,	,	PUNCT
admet-942	938	42	d.t	d.t	PROPN
admet-942	938	43	.	.	PROPN
admet-942	938	44	breault	breault	PROPN
admet-942	938	45	,	,	PUNCT
admet-942	938	46	d.e	d.e	PROPN
admet-942	938	47	.	.	PROPN
admet-942	938	48	ingber	ingber	PROPN
admet-942	938	49	.	.	PUNCT
admet-942	939	1	development	development	NOUN
admet-942	939	2	of	of	ADP
admet-942	939	3	a	a	DET
admet-942	939	4	primary	primary	ADJ
admet-942	939	5	human	human	ADJ
admet-942	939	6	small	small	ADJ
admet-942	939	7	intestine	intestine	NOUN
admet-942	939	8	-	-	PUNCT
admet-942	939	9	on	on	ADP
admet-942	939	10	-	-	PUNCT
admet-942	939	11	a	a	DET
admet-942	939	12	-	-	PUNCT
admet-942	939	13	chip	chip	NOUN
admet-942	939	14	using	use	VERB
admet-942	939	15	biopsy	biopsy	NOUN
admet-942	939	16	-	-	PUNCT
admet-942	939	17	derived	derive	VERB
admet-942	939	18	organoids	organoid	NOUN
admet-942	939	19	.	.	PUNCT
admet-942	940	1	scientific	scientific	ADJ
admet-942	940	2	reports	report	NOUN
admet-942	940	3	8	8	NUM
admet-942	940	4	(	(	PUNCT
admet-942	940	5	2018	2018	NUM
admet-942	940	6	)	)	PUNCT
admet-942	940	7	2871	2871	NUM
admet-942	940	8	.	.	PUNCT
admet-942	941	1	https://doi.org/10.1038/s41598-018-21201-7	https://doi.org/10.1038/s41598-018-21201-7	PROPN
admet-942	941	2	.	.	PUNCT
admet-942	942	1	https://doi.org/10.1063/1.5038337	https://doi.org/10.1063/1.5038337	PROPN
admet-942	942	2	https://doi.org/10.1016/j.drudis.2019.03.011	https://doi.org/10.1016/j.drudis.2019.03.011	VERB
admet-942	942	3	https://doi.org/10.1002/adhm.201500040	https://doi.org/10.1002/adhm.201500040	PART
admet-942	942	4	https://doi.org/10.1016/j.actbio.2016.11.010	https://doi.org/10.1016/j.actbio.2016.11.010	NUM
admet-942	942	5	https://doi.org/10.1016/j.toxlet.2016.06.1586	https://doi.org/10.1016/j.toxlet.2016.06.1586	ADJ
admet-942	942	6	https://doi.org/10.1039/c3ib40049b	https://doi.org/10.1039/c3ib40049b	PROPN
admet-942	942	7	https://doi.org/10.1039/c4lc01252f	https://doi.org/10.1039/c4lc01252f	PROPN
admet-942	942	8	https://doi.org/10.3389/fbioe.2019.00003	https://doi.org/10.3389/fbioe.2019.00003	PROPN
admet-942	942	9	https://doi.org/10.1016/j.bej.2019.107469	https://doi.org/10.1016/j.bej.2019.107469	X
admet-942	942	10	https://doi.org/10.1016/j.addr.2018.10.010	https://doi.org/10.1016/j.addr.2018.10.010	PROPN
admet-942	942	11	https://doi.org/10.1016/j.addr.2018.10.010	https://doi.org/10.1016/j.addr.2018.10.010	PROPN
admet-942	942	12	https://doi.org/10.1016/j.jcmgh.2017.12.010	https://doi.org/10.1016/j.jcmgh.2017.12.010	NOUN
admet-942	942	13	https://doi.org/10.1016/j.jcmgh.2018.01.016	https://doi.org/10.1016/j.jcmgh.2018.01.016	PROPN
admet-942	942	14	https://doi.org/10.1038/s41598-018-21201-7	https://doi.org/10.1038/s41598-018-21201-7	NUM
admet-942	942	15	admet	admet	PROPN
admet-942	942	16	&	&	CCONJ
admet-942	942	17	dmpk	dmpk	PROPN
admet-942	942	18	9(2	9(2	NUM
admet-942	942	19	)	)	PUNCT
admet-942	942	20	(	(	PUNCT
admet-942	942	21	2021	2021	NUM
admet-942	942	22	)	)	PUNCT
admet-942	942	23	111	111	NUM
admet-942	942	24	-	-	SYM
admet-942	942	25	141	141	NUM
admet-942	942	26	organ	organ	NOUN
admet-942	942	27	-	-	PUNCT
admet-942	942	28	on	on	ADP
admet-942	942	29	-	-	PUNCT
admet-942	942	30	a	a	DET
admet-942	942	31	-	-	PUNCT
admet-942	942	32	chip	chip	NOUN
admet-942	942	33	systems	system	NOUN
admet-942	942	34	for	for	ADP
admet-942	942	35	new	new	ADJ
admet-942	942	36	drugs	drug	NOUN
admet-942	942	37	development	development	NOUN
admet-942	942	38	doi	doi	PROPN
admet-942	942	39	:	:	PUNCT
admet-942	942	40	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	942	41	139	139	NUM
admet-942	942	42	[	[	SYM
admet-942	942	43	107	107	NUM
admet-942	942	44	]	]	X
admet-942	942	45	n.	n.	PROPN
admet-942	942	46	freyer	freyer	PROPN
admet-942	942	47	,	,	PUNCT
admet-942	942	48	s.	s.	PROPN
admet-942	942	49	greuel	greuel	PROPN
admet-942	942	50	,	,	PUNCT
admet-942	942	51	f.	f.	PROPN
admet-942	942	52	knöspel	knöspel	PROPN
admet-942	942	53	,	,	PUNCT
admet-942	942	54	f.	f.	PROPN
admet-942	942	55	gerstmann	gerstmann	PROPN
admet-942	942	56	,	,	PUNCT
admet-942	942	57	l.	l.	PROPN
admet-942	942	58	storch	storch	PROPN
admet-942	942	59	,	,	PUNCT
admet-942	942	60	g.	g.	PROPN
admet-942	942	61	damm	damm	PROPN
admet-942	942	62	,	,	PUNCT
admet-942	942	63	d.	d.	PROPN
admet-942	942	64	seehofer	seehofer	PROPN
admet-942	942	65	,	,	PUNCT
admet-942	942	66	j.f	j.f	PROPN
admet-942	942	67	.	.	PROPN
admet-942	942	68	harris	harris	PROPN
admet-942	942	69	,	,	PUNCT
admet-942	942	70	r.	r.	PROPN
admet-942	942	71	iyer	iyer	PROPN
admet-942	942	72	,	,	PUNCT
admet-942	942	73	f.	f.	PROPN
admet-942	942	74	schubert	schubert	PROPN
admet-942	942	75	,	,	PUNCT
admet-942	942	76	k.	k.	PROPN
admet-942	942	77	zeilinger	zeilinger	PROPN
admet-942	942	78	.	.	PUNCT
admet-942	943	1	microscale	microscale	ADJ
admet-942	943	2	3d	3d	NUM
admet-942	943	3	liver	liver	NOUN
admet-942	943	4	bioreactor	bioreactor	NOUN
admet-942	943	5	for	for	ADP
admet-942	943	6	in	in	X
admet-942	943	7	vitro	vitro	X
admet-942	943	8	hepatotoxicity	hepatotoxicity	NOUN
admet-942	943	9	testing	testing	NOUN
admet-942	943	10	under	under	ADP
admet-942	943	11	perfusion	perfusion	NOUN
admet-942	943	12	conditions	condition	NOUN
admet-942	943	13	.	.	PUNCT
admet-942	944	1	bioengineering	bioengineere	VERB
admet-942	944	2	5	5	NUM
admet-942	944	3	(	(	PUNCT
admet-942	944	4	2018	2018	NUM
admet-942	944	5	)	)	PUNCT
admet-942	944	6	.	.	PUNCT
admet-942	945	1	https://doi.org/10.3390/bioengineering5010024	https://doi.org/10.3390/bioengineering5010024	PROPN
admet-942	945	2	.	.	PUNCT
admet-942	946	1	[	[	X
admet-942	946	2	108	108	NUM
admet-942	946	3	]	]	PUNCT
admet-942	946	4	t.	t.	PROPN
admet-942	946	5	kostrzewski	kostrzewski	PROPN
admet-942	946	6	,	,	PUNCT
admet-942	946	7	t.	t.	PROPN
admet-942	946	8	cornforth	cornforth	PROPN
admet-942	946	9	,	,	PUNCT
admet-942	946	10	s.a	s.a	PROPN
admet-942	946	11	.	.	PROPN
admet-942	946	12	snow	snow	PROPN
admet-942	946	13	,	,	PUNCT
admet-942	946	14	l.	l.	PROPN
admet-942	946	15	ouro	ouro	PROPN
admet-942	946	16	-	-	PUNCT
admet-942	946	17	gnao	gnao	PROPN
admet-942	946	18	,	,	PUNCT
admet-942	946	19	c.	c.	PROPN
admet-942	946	20	rowe	rowe	PROPN
admet-942	946	21	,	,	PUNCT
admet-942	946	22	e.m	e.m	PROPN
admet-942	946	23	.	.	PROPN
admet-942	946	24	large	large	ADJ
admet-942	946	25	,	,	PUNCT
admet-942	946	26	d.j	d.j	PROPN
admet-942	946	27	.	.	PROPN
admet-942	946	28	hughes	hughes	PROPN
admet-942	946	29	.	.	PUNCT
admet-942	947	1	threedimensional	threedimensional	PROPN
admet-942	947	2	perfused	perfuse	VERB
admet-942	947	3	human	human	NOUN
admet-942	947	4	in	in	ADP
admet-942	947	5	vitro	vitro	X
admet-942	947	6	model	model	NOUN
admet-942	947	7	of	of	ADP
admet-942	947	8	non	non	ADJ
admet-942	947	9	-	-	ADJ
admet-942	947	10	alcoholic	alcoholic	ADJ
admet-942	947	11	fatty	fatty	NOUN
admet-942	947	12	liver	liver	NOUN
admet-942	947	13	disease	disease	NOUN
admet-942	947	14	.	.	PUNCT
admet-942	948	1	world	world	PROPN
admet-942	948	2	journal	journal	PROPN
admet-942	948	3	of	of	ADP
admet-942	948	4	gastroenterology	gastroenterology	NOUN
admet-942	948	5	23	23	NUM
admet-942	948	6	(	(	PUNCT
admet-942	948	7	2017	2017	NUM
admet-942	948	8	)	)	PUNCT
admet-942	948	9	204	204	NUM
admet-942	948	10	-	-	SYM
admet-942	948	11	215	215	NUM
admet-942	948	12	.	.	PUNCT
admet-942	949	1	https://doi.org/10.3748/wjg.v23.i2.204	https://doi.org/10.3748/wjg.v23.i2.204	ADV
admet-942	949	2	.	.	PUNCT
admet-942	950	1	[	[	X
admet-942	950	2	109	109	NUM
admet-942	950	3	]	]	PUNCT
admet-942	950	4	a.	a.	NOUN
admet-942	950	5	bhalerao	bhalerao	PROPN
admet-942	950	6	,	,	PUNCT
admet-942	950	7	f.	f.	PROPN
admet-942	950	8	sivandzade	sivandzade	PROPN
admet-942	950	9	,	,	PUNCT
admet-942	950	10	s.r	s.r	PROPN
admet-942	950	11	.	.	PROPN
admet-942	950	12	archie	archie	PROPN
admet-942	950	13	,	,	PUNCT
admet-942	950	14	e.a	e.a	PROPN
admet-942	950	15	.	.	PROPN
admet-942	950	16	chowdhury	chowdhury	PROPN
admet-942	950	17	,	,	PUNCT
admet-942	950	18	b.	b.	PROPN
admet-942	950	19	noorani	noorani	PROPN
admet-942	950	20	,	,	PUNCT
admet-942	950	21	l.	l.	PROPN
admet-942	950	22	cucullo	cucullo	PROPN
admet-942	950	23	.	.	PUNCT
admet-942	951	1	in	in	ADP
admet-942	951	2	vitro	vitro	X
admet-942	951	3	modeling	modeling	NOUN
admet-942	951	4	of	of	ADP
admet-942	951	5	the	the	DET
admet-942	951	6	neurovascular	neurovascular	ADJ
admet-942	951	7	unit	unit	NOUN
admet-942	951	8	:	:	PUNCT
admet-942	951	9	advances	advance	NOUN
admet-942	951	10	in	in	ADP
admet-942	951	11	the	the	DET
admet-942	951	12	field	field	NOUN
admet-942	951	13	.	.	PUNCT
admet-942	952	1	fluids	fluid	NOUN
admet-942	952	2	and	and	CCONJ
admet-942	952	3	barriers	barrier	NOUN
admet-942	952	4	of	of	ADP
admet-942	952	5	the	the	DET
admet-942	952	6	cns	cns	PROPN
admet-942	952	7	17	17	NUM
admet-942	952	8	(	(	PUNCT
admet-942	952	9	2020	2020	NUM
admet-942	952	10	)	)	PUNCT
admet-942	952	11	22	22	NUM
admet-942	952	12	.	.	PUNCT
admet-942	953	1	https://doi.org/10.1186/s12987-020-00183-7	https://doi.org/10.1186/s12987-020-00183-7	NUM
admet-942	953	2	.	.	PUNCT
admet-942	954	1	[	[	X
admet-942	954	2	110	110	NUM
admet-942	954	3	]	]	X
admet-942	954	4	f.	f.	PROPN
admet-942	954	5	yin	yin	PROPN
admet-942	954	6	,	,	PUNCT
admet-942	954	7	y.	y.	PROPN
admet-942	954	8	zhu	zhu	PROPN
admet-942	954	9	,	,	PUNCT
admet-942	954	10	m.	m.	PROPN
admet-942	954	11	zhang	zhang	PROPN
admet-942	954	12	,	,	PUNCT
admet-942	954	13	h.	h.	PROPN
admet-942	954	14	yu	yu	PROPN
admet-942	954	15	,	,	PUNCT
admet-942	954	16	w.	w.	PROPN
admet-942	954	17	chen	chen	PROPN
admet-942	954	18	,	,	PUNCT
admet-942	954	19	j.	j.	PROPN
admet-942	954	20	qin	qin	PROPN
admet-942	954	21	.	.	PUNCT
admet-942	955	1	a	a	DET
admet-942	955	2	3d	3d	NUM
admet-942	955	3	human	human	ADJ
admet-942	955	4	placenta	placenta	NOUN
admet-942	955	5	-	-	PUNCT
admet-942	955	6	on	on	ADP
admet-942	955	7	-	-	PUNCT
admet-942	955	8	a	a	DET
admet-942	955	9	-	-	PUNCT
admet-942	955	10	chip	chip	NOUN
admet-942	955	11	model	model	NOUN
admet-942	955	12	to	to	PART
admet-942	955	13	probe	probe	VERB
admet-942	955	14	nanoparticle	nanoparticle	NOUN
admet-942	955	15	exposure	exposure	NOUN
admet-942	955	16	at	at	ADP
admet-942	955	17	the	the	DET
admet-942	955	18	placental	placental	ADJ
admet-942	955	19	barrier	barrier	NOUN
admet-942	955	20	.	.	PUNCT
admet-942	956	1	toxicology	toxicology	NOUN
admet-942	956	2	in	in	ADP
admet-942	956	3	vitro	vitro	X
admet-942	956	4	54	54	NUM
admet-942	956	5	(	(	PUNCT
admet-942	956	6	2019	2019	NUM
admet-942	956	7	)	)	PUNCT
admet-942	956	8	105	105	NUM
admet-942	956	9	-	-	SYM
admet-942	956	10	113	113	NUM
admet-942	956	11	.	.	PUNCT
admet-942	957	1	https://doi.org/10.1016/j.tiv.2018.08.014	https://doi.org/10.1016/j.tiv.2018.08.014	PROPN
admet-942	957	2	.	.	PUNCT
admet-942	958	1	[	[	X
admet-942	958	2	111	111	NUM
admet-942	958	3	]	]	PUNCT
admet-942	958	4	e.	e.	PROPN
admet-942	958	5	knyazev	knyazev	PROPN
admet-942	958	6	,	,	PUNCT
admet-942	958	7	a.	a.	PROPN
admet-942	958	8	khristichenko	khristichenko	PROPN
admet-942	958	9	,	,	PUNCT
admet-942	958	10	d.	d.	PROPN
admet-942	958	11	maltseva	maltseva	PROPN
admet-942	958	12	,	,	PUNCT
admet-942	958	13	t.	t.	PROPN
admet-942	958	14	gerasimenko	gerasimenko	PROPN
admet-942	958	15	,	,	PUNCT
admet-942	958	16	o.	o.	PROPN
admet-942	958	17	kindeeva	kindeeva	PROPN
admet-942	958	18	,	,	PUNCT
admet-942	958	19	v.	v.	PROPN
admet-942	958	20	petrov	petrov	PROPN
admet-942	958	21	,	,	PUNCT
admet-942	958	22	d.	d.	PROPN
admet-942	958	23	sakharov	sakharov	PROPN
admet-942	958	24	.	.	PUNCT
admet-942	959	1	placenta	placenta	PROPN
admet-942	959	2	-	-	PUNCT
admet-942	959	3	on	on	ADP
admet-942	959	4	-	-	PUNCT
admet-942	959	5	a	a	DET
admet-942	959	6	-	-	PUNCT
admet-942	959	7	chip	chip	NOUN
admet-942	959	8	model	model	NOUN
admet-942	959	9	for	for	ADP
admet-942	959	10	assessing	assess	VERB
admet-942	959	11	the	the	DET
admet-942	959	12	transport	transport	NOUN
admet-942	959	13	and	and	CCONJ
admet-942	959	14	toxicity	toxicity	NOUN
admet-942	959	15	of	of	ADP
admet-942	959	16	xenobiotics	xenobiotics	PROPN
admet-942	959	17	in	in	ADP
admet-942	959	18	vitro	vitro	X
admet-942	959	19	.	.	PUNCT
admet-942	960	1	placenta	placenta	PROPN
admet-942	960	2	83	83	NUM
admet-942	960	3	(	(	PUNCT
admet-942	960	4	2019	2019	NUM
admet-942	960	5	)	)	PUNCT
admet-942	960	6	e59	e59	NOUN
admet-942	960	7	-	-	PUNCT
admet-942	960	8	e60	e60	NOUN
admet-942	960	9	.	.	PUNCT
admet-942	961	1	https://doi.org/10.1016/j.placenta.2019.06.195	https://doi.org/10.1016/j.placenta.2019.06.195	NOUN
admet-942	961	2	.	.	PUNCT
admet-942	962	1	[	[	X
admet-942	962	2	112	112	NUM
admet-942	962	3	]	]	X
admet-942	962	4	n.	n.	PROPN
admet-942	962	5	manafi	manafi	PROPN
admet-942	962	6	,	,	PUNCT
admet-942	962	7	f.	f.	PROPN
admet-942	962	8	shokri	shokri	PROPN
admet-942	962	9	,	,	PUNCT
admet-942	962	10	k.	k.	PROPN
admet-942	962	11	achberger	achberger	PROPN
admet-942	962	12	,	,	PUNCT
admet-942	962	13	m.	m.	NOUN
admet-942	962	14	hirayama	hirayama	PROPN
admet-942	962	15	,	,	PUNCT
admet-942	962	16	m.h	m.h	PROPN
admet-942	962	17	.	.	PROPN
admet-942	962	18	mohammadi	mohammadi	PROPN
admet-942	962	19	,	,	PUNCT
admet-942	962	20	f.	f.	PROPN
admet-942	962	21	noorizadeh	noorizadeh	PROPN
admet-942	962	22	,	,	PUNCT
admet-942	962	23	j.	j.	PROPN
admet-942	962	24	hong	hong	PROPN
admet-942	962	25	,	,	PUNCT
admet-942	962	26	s.	s.	PROPN
admet-942	962	27	liebau	liebau	PROPN
admet-942	962	28	,	,	PUNCT
admet-942	962	29	t.	t.	PROPN
admet-942	962	30	tsuji	tsuji	PROPN
admet-942	962	31	,	,	PUNCT
admet-942	962	32	p.m.j	p.m.j	PROPN
admet-942	962	33	.	.	PUNCT
admet-942	962	34	quinn	quinn	PROPN
admet-942	962	35	,	,	PUNCT
admet-942	962	36	a.	a.	PROPN
admet-942	962	37	mashaghi	mashaghi	PROPN
admet-942	962	38	.	.	PUNCT
admet-942	963	1	organoids	organoid	NOUN
admet-942	963	2	and	and	CCONJ
admet-942	963	3	organ	organ	NOUN
admet-942	963	4	chips	chip	NOUN
admet-942	963	5	in	in	ADP
admet-942	963	6	ophthalmology	ophthalmology	NOUN
admet-942	963	7	.	.	PUNCT
admet-942	964	1	the	the	DET
admet-942	964	2	ocular	ocular	ADJ
admet-942	964	3	surface	surface	NOUN
admet-942	964	4	19	19	NUM
admet-942	964	5	(	(	PUNCT
admet-942	964	6	2021	2021	NUM
admet-942	964	7	)	)	PUNCT
admet-942	964	8	1	1	NUM
admet-942	964	9	-	-	SYM
admet-942	964	10	15	15	NUM
admet-942	964	11	.	.	PUNCT
admet-942	964	12	https://doi.org/10.1016/j.jtos.2020.11.004	https://doi.org/10.1016/j.jtos.2020.11.004	X
admet-942	964	13	.	.	PUNCT
admet-942	965	1	[	[	X
admet-942	965	2	113	113	NUM
admet-942	965	3	]	]	X
admet-942	965	4	d.s	d.s	PROPN
admet-942	965	5	.	.	PROPN
admet-942	965	6	park	park	PROPN
admet-942	965	7	,	,	PUNCT
admet-942	965	8	j.h	j.h	PROPN
admet-942	965	9	.	.	PROPN
admet-942	965	10	kim	kim	PROPN
admet-942	965	11	,	,	PUNCT
admet-942	965	12	h.s	h.s	PROPN
admet-942	965	13	.	.	PROPN
admet-942	965	14	kim	kim	PROPN
admet-942	965	15	,	,	PUNCT
admet-942	965	16	j.h	j.h	PROPN
admet-942	965	17	.	.	PROPN
admet-942	965	18	park	park	PROPN
admet-942	965	19	,	,	PUNCT
admet-942	965	20	j.k	j.k	PROPN
admet-942	965	21	.	.	PROPN
admet-942	965	22	shin	shin	PROPN
admet-942	965	23	,	,	PUNCT
admet-942	965	24	m.	m.	PROPN
admet-942	965	25	lee	lee	PROPN
admet-942	965	26	.	.	PUNCT
admet-942	966	1	a	a	DET
admet-942	966	2	foveated	foveate	VERB
admet-942	966	3	-	-	PUNCT
admet-942	966	4	structure	structure	NOUN
admet-942	966	5	cmos	cmos	NOUN
admet-942	966	6	retina	retina	NOUN
admet-942	966	7	chip	chip	NOUN
admet-942	966	8	for	for	ADP
admet-942	966	9	edge	edge	NOUN
admet-942	966	10	detection	detection	NOUN
admet-942	966	11	with	with	ADP
admet-942	966	12	local	local	ADJ
admet-942	966	13	light	light	ADJ
admet-942	966	14	adaptation	adaptation	NOUN
admet-942	966	15	.	.	PUNCT
admet-942	967	1	en	en	ADP
admet-942	967	2	:	:	PUNCT
admet-942	967	3	sensors	sensor	NOUN
admet-942	967	4	actuators	actuator	NOUN
admet-942	967	5	,	,	PUNCT
admet-942	967	6	a	a	DET
admet-942	967	7	phys	phy	NOUN
admet-942	967	8	.	.	PUNCT
admet-942	967	9	,	,	PUNCT
admet-942	967	10	elsevier	elsevier	NOUN
admet-942	967	11	,	,	PUNCT
admet-942	967	12	2003	2003	NUM
admet-942	967	13	:	:	PUNCT
admet-942	968	1	pp	pp	ADJ
admet-942	968	2	.	.	PUNCT
admet-942	969	1	75	75	NUM
admet-942	969	2	-	-	SYM
admet-942	969	3	80	80	NUM
admet-942	969	4	.	.	PUNCT
admet-942	970	1	https://doi.org/10.1016/s0924-4247(03)00292-9	https://doi.org/10.1016/s0924-4247(03)00292-9	NOUN
admet-942	970	2	.	.	PUNCT
admet-942	971	1	[	[	X
admet-942	971	2	114	114	NUM
admet-942	971	3	]	]	PUNCT
admet-942	971	4	a.	a.	NOUN
admet-942	971	5	grosberg	grosberg	PROPN
admet-942	971	6	,	,	PUNCT
admet-942	971	7	a.p	a.p	PROPN
admet-942	971	8	.	.	PROPN
admet-942	971	9	nesmith	nesmith	PROPN
admet-942	971	10	,	,	PUNCT
admet-942	971	11	j.a	j.a	PROPN
admet-942	971	12	.	.	PROPN
admet-942	971	13	goss	goss	PROPN
admet-942	971	14	,	,	PUNCT
admet-942	971	15	m.d	m.d	PROPN
admet-942	971	16	.	.	PROPN
admet-942	971	17	brigham	brigham	PROPN
admet-942	971	18	,	,	PUNCT
admet-942	971	19	m.l	m.l	PROPN
admet-942	971	20	.	.	PROPN
admet-942	971	21	mccain	mccain	PROPN
admet-942	971	22	,	,	PUNCT
admet-942	971	23	k.k	k.k	PROPN
admet-942	971	24	.	.	PROPN
admet-942	971	25	parker	parker	PROPN
admet-942	971	26	.	.	PUNCT
admet-942	972	1	muscle	muscle	NOUN
admet-942	972	2	on	on	ADP
admet-942	972	3	a	a	DET
admet-942	972	4	chip	chip	NOUN
admet-942	972	5	:	:	PUNCT
admet-942	972	6	in	in	ADP
admet-942	972	7	vitro	vitro	X
admet-942	972	8	contractility	contractility	NOUN
admet-942	972	9	assays	assay	NOUN
admet-942	972	10	for	for	ADP
admet-942	972	11	smooth	smooth	ADJ
admet-942	972	12	and	and	CCONJ
admet-942	972	13	striated	striated	ADJ
admet-942	972	14	muscle	muscle	NOUN
admet-942	972	15	.	.	PUNCT
admet-942	973	1	journal	journal	NOUN
admet-942	973	2	of	of	ADP
admet-942	973	3	pharmacological	pharmacological	ADJ
admet-942	973	4	and	and	CCONJ
admet-942	973	5	toxicological	toxicological	ADJ
admet-942	973	6	methods	method	NOUN
admet-942	973	7	65	65	NUM
admet-942	973	8	(	(	PUNCT
admet-942	973	9	2012	2012	NUM
admet-942	973	10	)	)	PUNCT
admet-942	973	11	126	126	NUM
admet-942	973	12	-	-	SYM
admet-942	973	13	135	135	NUM
admet-942	973	14	.	.	PUNCT
admet-942	974	1	https://doi.org/10.1016/j.vascn.2012.04.001	https://doi.org/10.1016/j.vascn.2012.04.001	NOUN
admet-942	974	2	.	.	PUNCT
admet-942	975	1	[	[	X
admet-942	975	2	115	115	NUM
admet-942	975	3	]	]	X
admet-942	975	4	b.p	b.p	PROPN
admet-942	975	5	.	.	PROPN
admet-942	975	6	jena	jena	PROPN
admet-942	975	7	,	,	PUNCT
admet-942	975	8	d.l	d.l	PROPN
admet-942	975	9	.	.	PROPN
admet-942	975	10	gatti	gatti	PROPN
admet-942	975	11	,	,	PUNCT
admet-942	975	12	s.	s.	PROPN
admet-942	975	13	arslanturk	arslanturk	PROPN
admet-942	975	14	,	,	PUNCT
admet-942	975	15	s.	s.	PROPN
admet-942	975	16	pernal	pernal	PROPN
admet-942	975	17	,	,	PUNCT
admet-942	975	18	d.j	d.j	PROPN
admet-942	975	19	.	.	PROPN
admet-942	975	20	taatjes	taatjes	PROPN
admet-942	975	21	.	.	PUNCT
admet-942	976	1	human	human	ADJ
admet-942	976	2	skeletal	skeletal	ADJ
admet-942	976	3	muscle	muscle	NOUN
admet-942	976	4	cell	cell	NOUN
admet-942	976	5	atlas	atlas	PROPN
admet-942	976	6	:	:	PUNCT
admet-942	976	7	unraveling	unravel	VERB
admet-942	976	8	cellular	cellular	ADJ
admet-942	976	9	secrets	secret	NOUN
admet-942	976	10	utilizing	utilize	VERB
admet-942	976	11	‘	'	PUNCT
admet-942	976	12	muscle	muscle	NOUN
admet-942	976	13	-	-	PUNCT
admet-942	976	14	on	on	ADP
admet-942	976	15	-	-	PUNCT
admet-942	976	16	a	a	DET
admet-942	976	17	-	-	PUNCT
admet-942	976	18	chip	chip	NOUN
admet-942	976	19	’	'	PUNCT
admet-942	976	20	,	,	PUNCT
admet-942	976	21	differential	differential	ADJ
admet-942	976	22	expansion	expansion	NOUN
admet-942	976	23	microscopy	microscopy	NOUN
admet-942	976	24	,	,	PUNCT
admet-942	976	25	mass	mass	ADJ
admet-942	976	26	spectrometry	spectrometry	NOUN
admet-942	976	27	,	,	PUNCT
admet-942	976	28	nanothermometry	nanothermometry	NOUN
admet-942	976	29	and	and	CCONJ
admet-942	976	30	machine	machine	NOUN
admet-942	976	31	learning	learning	NOUN
admet-942	976	32	.	.	PUNCT
admet-942	977	1	micron	micron	NOUN
admet-942	977	2	117	117	NUM
admet-942	977	3	(	(	PUNCT
admet-942	977	4	2019	2019	NUM
admet-942	977	5	)	)	PUNCT
admet-942	977	6	55	55	NUM
admet-942	977	7	-	-	SYM
admet-942	977	8	59	59	NUM
admet-942	977	9	.	.	PUNCT
admet-942	977	10	https://doi.org/10.1016/j.micron.2018.11.002	https://doi.org/10.1016/j.micron.2018.11.002	NOUN
admet-942	977	11	.	.	PUNCT
admet-942	978	1	[	[	X
admet-942	978	2	116	116	X
admet-942	978	3	]	]	X
admet-942	978	4	q.	q.	PROPN
admet-942	978	5	tang	tang	PROPN
admet-942	978	6	,	,	PUNCT
admet-942	978	7	x.	x.	PROPN
admet-942	978	8	li	li	PROPN
admet-942	978	9	,	,	PUNCT
admet-942	978	10	c.	c.	PROPN
admet-942	978	11	lai	lai	PROPN
admet-942	978	12	,	,	PUNCT
admet-942	978	13	l.	l.	PROPN
admet-942	978	14	li	li	PROPN
admet-942	978	15	,	,	PUNCT
admet-942	978	16	h.	h.	PROPN
admet-942	978	17	wu	wu	PROPN
admet-942	978	18	,	,	PUNCT
admet-942	978	19	y.	y.	PROPN
admet-942	978	20	wang	wang	PROPN
admet-942	978	21	,	,	PUNCT
admet-942	978	22	x.	x.	PROPN
admet-942	978	23	shi	shi	PROPN
admet-942	978	24	.	.	PUNCT
admet-942	979	1	fabrication	fabrication	NOUN
admet-942	979	2	of	of	ADP
admet-942	979	3	a	a	DET
admet-942	979	4	hydroxyapatite	hydroxyapatite	NOUN
admet-942	979	5	-	-	PUNCT
admet-942	979	6	pdms	pdms	NOUN
admet-942	979	7	microfluidic	microfluidic	ADJ
admet-942	979	8	chip	chip	NOUN
admet-942	979	9	for	for	ADP
admet-942	979	10	bone	bone	NOUN
admet-942	979	11	-	-	PUNCT
admet-942	979	12	related	relate	VERB
admet-942	979	13	cell	cell	NOUN
admet-942	979	14	culture	culture	NOUN
admet-942	979	15	and	and	CCONJ
admet-942	979	16	drug	drug	NOUN
admet-942	979	17	screening	screening	NOUN
admet-942	979	18	.	.	PUNCT
admet-942	980	1	bioactive	bioactive	ADJ
admet-942	980	2	materials	material	NOUN
admet-942	980	3	6	6	NUM
admet-942	980	4	(	(	PUNCT
admet-942	980	5	2021	2021	NUM
admet-942	980	6	)	)	PUNCT
admet-942	980	7	169	169	NUM
admet-942	980	8	-	-	SYM
admet-942	980	9	178	178	NUM
admet-942	980	10	.	.	PUNCT
admet-942	981	1	https://doi.org/10.1016/j.bioactmat.2020.07.016	https://doi.org/10.1016/j.bioactmat.2020.07.016	PROPN
admet-942	981	2	.	.	PUNCT
admet-942	982	1	[	[	X
admet-942	982	2	117	117	NUM
admet-942	982	3	]	]	X
admet-942	982	4	e.l	e.l	PROPN
admet-942	982	5	.	.	PROPN
admet-942	982	6	george	george	PROPN
admet-942	982	7	,	,	PUNCT
admet-942	982	8	s.l	s.l	PROPN
admet-942	982	9	.	.	PROPN
admet-942	982	10	truesdell	truesdell	PROPN
admet-942	982	11	,	,	PUNCT
admet-942	982	12	s.l	s.l	PROPN
admet-942	982	13	.	.	PROPN
admet-942	982	14	york	york	PROPN
admet-942	982	15	,	,	PUNCT
admet-942	982	16	m.m	m.m	PROPN
admet-942	982	17	.	.	PROPN
admet-942	982	18	saunders	saunders	PROPN
admet-942	982	19	.	.	PUNCT
admet-942	983	1	lab	lab	NOUN
admet-942	983	2	-	-	PUNCT
admet-942	983	3	on	on	ADP
admet-942	983	4	-	-	PUNCT
admet-942	983	5	a	a	DET
admet-942	983	6	-	-	PUNCT
admet-942	983	7	chip	chip	NOUN
admet-942	983	8	platforms	platform	NOUN
admet-942	983	9	for	for	ADP
admet-942	983	10	quantification	quantification	NOUN
admet-942	983	11	of	of	ADP
admet-942	983	12	multicellular	multicellular	ADJ
admet-942	983	13	interactions	interaction	NOUN
admet-942	983	14	in	in	ADP
admet-942	983	15	bone	bone	NOUN
admet-942	983	16	remodeling	remodeling	NOUN
admet-942	983	17	.	.	PUNCT
admet-942	984	1	experimental	experimental	ADJ
admet-942	984	2	cell	cell	NOUN
admet-942	984	3	research	research	NOUN
admet-942	984	4	365	365	NUM
admet-942	984	5	(	(	PUNCT
admet-942	984	6	2018	2018	NUM
admet-942	984	7	)	)	PUNCT
admet-942	984	8	106	106	NUM
admet-942	984	9	-	-	SYM
admet-942	984	10	118	118	NUM
admet-942	984	11	.	.	PUNCT
admet-942	985	1	https://doi.org/10.1016/j.yexcr.2018.02.027	https://doi.org/10.1016/j.yexcr.2018.02.027	NOUN
admet-942	985	2	.	.	PUNCT
admet-942	986	1	[	[	X
admet-942	986	2	118	118	NUM
admet-942	986	3	]	]	X
admet-942	986	4	y.	y.	PROPN
admet-942	986	5	chen	chen	PROPN
admet-942	986	6	,	,	PUNCT
admet-942	986	7	d.	d.	PROPN
admet-942	986	8	gao	gao	PROPN
admet-942	986	9	,	,	PUNCT
admet-942	986	10	y.	y.	PROPN
admet-942	986	11	wang	wang	PROPN
admet-942	986	12	,	,	PUNCT
admet-942	986	13	s.	s.	PROPN
admet-942	986	14	lin	lin	PROPN
admet-942	986	15	,	,	PUNCT
admet-942	986	16	y.	y.	PROPN
admet-942	986	17	jiang	jiang	PROPN
admet-942	986	18	.	.	PUNCT
admet-942	987	1	a	a	DET
admet-942	987	2	novel	novel	ADJ
admet-942	987	3	3d	3d	NUM
admet-942	987	4	breast	breast	NOUN
admet-942	987	5	-	-	PUNCT
admet-942	987	6	cancer	cancer	NOUN
admet-942	987	7	-	-	PUNCT
admet-942	987	8	on	on	ADP
admet-942	987	9	-	-	PUNCT
admet-942	987	10	chip	chip	NOUN
admet-942	987	11	platform	platform	NOUN
admet-942	987	12	for	for	ADP
admet-942	987	13	therapeutic	therapeutic	ADJ
admet-942	987	14	evaluation	evaluation	NOUN
admet-942	987	15	of	of	ADP
admet-942	987	16	drug	drug	NOUN
admet-942	987	17	delivery	delivery	NOUN
admet-942	987	18	systems	system	NOUN
admet-942	987	19	.	.	PUNCT
admet-942	988	1	analytica	analytica	PROPN
admet-942	988	2	chimica	chimica	PROPN
admet-942	988	3	acta	acta	PROPN
admet-942	988	4	1036	1036	NUM
admet-942	988	5	(	(	PUNCT
admet-942	988	6	2018	2018	NUM
admet-942	988	7	)	)	PUNCT
admet-942	988	8	97	97	NUM
admet-942	988	9	-	-	SYM
admet-942	988	10	106	106	NUM
admet-942	988	11	.	.	PUNCT
admet-942	989	1	https://doi.org/10.1016/j.aca.2018.06.038	https://doi.org/10.1016/j.aca.2018.06.038	PROPN
admet-942	989	2	.	.	PUNCT
admet-942	990	1	[	[	X
admet-942	990	2	119	119	NUM
admet-942	990	3	]	]	PUNCT
admet-942	990	4	x.	x.	PROPN
admet-942	990	5	zhang	zhang	PROPN
admet-942	990	6	,	,	PUNCT
admet-942	990	7	x.	x.	PROPN
admet-942	990	8	lu	lu	PROPN
admet-942	990	9	,	,	PUNCT
admet-942	990	10	w.	w.	PROPN
admet-942	990	11	gao	gao	PROPN
admet-942	990	12	,	,	PUNCT
admet-942	990	13	y.	y.	PROPN
admet-942	990	14	wang	wang	PROPN
admet-942	990	15	,	,	PUNCT
admet-942	990	16	c.	c.	PROPN
admet-942	990	17	jia	jia	PROPN
admet-942	990	18	,	,	PUNCT
admet-942	990	19	h.	h.	PROPN
admet-942	990	20	cong	cong	PROPN
admet-942	990	21	.	.	PUNCT
admet-942	991	1	a	a	DET
admet-942	991	2	label	label	NOUN
admet-942	991	3	-	-	PUNCT
admet-942	991	4	free	free	ADJ
admet-942	991	5	microfluidic	microfluidic	ADJ
admet-942	991	6	chip	chip	NOUN
admet-942	991	7	for	for	ADP
admet-942	991	8	the	the	DET
admet-942	991	9	highly	highly	ADV
admet-942	991	10	selective	selective	ADJ
admet-942	991	11	isolation	isolation	NOUN
admet-942	991	12	of	of	ADP
admet-942	991	13	single	single	ADJ
admet-942	991	14	and	and	CCONJ
admet-942	991	15	cluster	cluster	NOUN
admet-942	991	16	ctcs	ctcs	NOUN
admet-942	991	17	from	from	ADP
admet-942	991	18	breast	breast	NOUN
admet-942	991	19	cancer	cancer	NOUN
admet-942	991	20	patients	patient	NOUN
admet-942	991	21	.	.	PUNCT
admet-942	992	1	translational	translational	ADJ
admet-942	992	2	oncology	oncology	NOUN
admet-942	992	3	14	14	NUM
admet-942	992	4	(	(	PUNCT
admet-942	992	5	2021	2021	NUM
admet-942	992	6	)	)	PUNCT
admet-942	992	7	100959	100959	NUM
admet-942	992	8	.	.	PUNCT
admet-942	993	1	https://doi.org/10.1016/j.tranon.2020.100959	https://doi.org/10.1016/j.tranon.2020.100959	NOUN
admet-942	993	2	.	.	PUNCT
admet-942	994	1	[	[	X
admet-942	994	2	120	120	NUM
admet-942	994	3	]	]	X
admet-942	994	4	k.s	k.s	PROPN
admet-942	994	5	.	.	PROPN
admet-942	994	6	mun	mun	PROPN
admet-942	994	7	,	,	PUNCT
admet-942	994	8	m.	m.	PROPN
admet-942	994	9	abu	abu	PROPN
admet-942	994	10	-	-	PUNCT
admet-942	994	11	el	el	PROPN
admet-942	994	12	-	-	PUNCT
admet-942	994	13	haija	haija	NOUN
admet-942	994	14	,	,	PUNCT
admet-942	994	15	j.d	j.d	PROPN
admet-942	994	16	.	.	PROPN
admet-942	994	17	nathan	nathan	PROPN
admet-942	994	18	,	,	PUNCT
admet-942	994	19	r.a	r.a	PROPN
admet-942	994	20	.	.	PROPN
admet-942	994	21	liddle	liddle	PROPN
admet-942	994	22	,	,	PUNCT
admet-942	994	23	a.p	a.p	PROPN
admet-942	994	24	.	.	PROPN
admet-942	994	25	naren	naren	PROPN
admet-942	994	26	.	.	PUNCT
admet-942	995	1	mo1373	mo1373	PROPN
admet-942	995	2	human	human	ADJ
admet-942	995	3	pancreas	pancrea	NOUN
admet-942	995	4	-	-	PUNCT
admet-942	995	5	on	on	ADP
admet-942	995	6	-	-	PUNCT
admet-942	995	7	achip	achip	NOUN
admet-942	995	8	to	to	PART
admet-942	995	9	study	study	VERB
admet-942	995	10	pressure	pressure	NOUN
admet-942	995	11	-	-	PUNCT
admet-942	995	12	induced	induce	VERB
admet-942	995	13	pancreatitis	pancreatitis	NOUN
admet-942	995	14	.	.	PUNCT
admet-942	996	1	gastroenterology	gastroenterology	NOUN
admet-942	996	2	158	158	NUM
admet-942	996	3	(	(	PUNCT
admet-942	996	4	2020	2020	NUM
admet-942	996	5	)	)	PUNCT
admet-942	996	6	s-868	s-868	PROPN
admet-942	996	7	.	.	PUNCT
admet-942	997	1	https://doi.org/10.1016/s0016-5085(20)32850-x	https://doi.org/10.1016/s0016-5085(20)32850-x	PROPN
admet-942	997	2	.	.	PUNCT
admet-942	998	1	[	[	X
admet-942	998	2	121	121	NUM
admet-942	998	3	]	]	PUNCT
admet-942	998	4	a.	a.	NOUN
admet-942	998	5	essaouiba	essaouiba	PROPN
admet-942	998	6	,	,	PUNCT
admet-942	998	7	t.	t.	PROPN
admet-942	998	8	okitsu	okitsu	PROPN
admet-942	998	9	,	,	PUNCT
admet-942	998	10	r.	r.	PROPN
admet-942	998	11	kinoshita	kinoshita	PROPN
admet-942	998	12	,	,	PUNCT
admet-942	998	13	r.	r.	PROPN
admet-942	998	14	jellali	jellali	PROPN
admet-942	998	15	,	,	PUNCT
admet-942	998	16	m.	m.	NOUN
admet-942	998	17	shinohara	shinohara	PROPN
admet-942	998	18	,	,	PUNCT
admet-942	998	19	m.	m.	NOUN
admet-942	998	20	danoy	danoy	PROPN
admet-942	998	21	,	,	PUNCT
admet-942	998	22	c.	c.	PROPN
admet-942	998	23	legallais	legallais	PROPN
admet-942	998	24	,	,	PUNCT
admet-942	998	25	y.	y.	PROPN
admet-942	998	26	sakai	sakai	PROPN
admet-942	998	27	,	,	PUNCT
admet-942	998	28	e.	e.	PROPN
admet-942	998	29	leclerc	leclerc	PROPN
admet-942	998	30	.	.	PUNCT
admet-942	999	1	development	development	NOUN
admet-942	999	2	of	of	ADP
admet-942	999	3	a	a	DET
admet-942	999	4	pancreas	pancreas	NOUN
admet-942	999	5	-	-	PUNCT
admet-942	999	6	liver	liver	NOUN
admet-942	999	7	organ	organ	NOUN
admet-942	999	8	-	-	PUNCT
admet-942	999	9	on	on	ADP
admet-942	999	10	-	-	PUNCT
admet-942	999	11	chip	chip	NOUN
admet-942	999	12	coculture	coculture	NOUN
admet-942	999	13	model	model	NOUN
admet-942	999	14	for	for	ADP
admet-942	999	15	organ	organ	NOUN
admet-942	999	16	-	-	PUNCT
admet-942	999	17	to	to	ADP
admet-942	999	18	-	-	PUNCT
admet-942	999	19	organ	organ	NOUN
admet-942	999	20	interaction	interaction	NOUN
admet-942	999	21	studies	study	NOUN
admet-942	999	22	.	.	PUNCT
admet-942	1000	1	biochemical	biochemical	ADJ
admet-942	1000	2	engineering	engineering	NOUN
admet-942	1000	3	journal	journal	PROPN
admet-942	1000	4	164	164	NUM
admet-942	1000	5	(	(	PUNCT
admet-942	1000	6	2020	2020	NUM
admet-942	1000	7	)	)	PUNCT
admet-942	1000	8	107783	107783	NUM
admet-942	1000	9	.	.	PUNCT
admet-942	1001	1	https://doi.org/10.1016/j.bej.2020.107783	https://doi.org/10.1016/j.bej.2020.107783	NOUN
admet-942	1001	2	.	.	PUNCT
admet-942	1002	1	[	[	X
admet-942	1002	2	122	122	NUM
admet-942	1002	3	]	]	PUNCT
admet-942	1002	4	j.	j.	PROPN
admet-942	1002	5	radhakrishnan	radhakrishnan	PROPN
admet-942	1002	6	,	,	PUNCT
admet-942	1002	7	s.	s.	PROPN
admet-942	1002	8	varadaraj	varadaraj	PROPN
admet-942	1002	9	,	,	PUNCT
admet-942	1002	10	s.k	s.k	PROPN
admet-942	1002	11	.	.	NOUN
admet-942	1002	12	dash	dash	NOUN
admet-942	1002	13	,	,	PUNCT
admet-942	1002	14	a.	a.	NOUN
admet-942	1002	15	sharma	sharma	PROPN
admet-942	1002	16	,	,	PUNCT
admet-942	1002	17	r.s	r.s	PROPN
admet-942	1002	18	.	.	PROPN
admet-942	1002	19	verma	verma	PROPN
admet-942	1002	20	.	.	PUNCT
admet-942	1003	1	organotypic	organotypic	ADJ
admet-942	1003	2	cancer	cancer	NOUN
admet-942	1003	3	tissue	tissue	NOUN
admet-942	1003	4	models	model	NOUN
admet-942	1003	5	for	for	ADP
admet-942	1003	6	drug	drug	NOUN
admet-942	1003	7	screening	screening	NOUN
admet-942	1003	8	:	:	PUNCT
admet-942	1003	9	3d	3d	NOUN
admet-942	1003	10	constructs	construct	NOUN
admet-942	1003	11	,	,	PUNCT
admet-942	1003	12	bioprinting	bioprinting	NOUN
admet-942	1003	13	and	and	CCONJ
admet-942	1003	14	microfluidic	microfluidic	ADJ
admet-942	1003	15	chips	chip	NOUN
admet-942	1003	16	.	.	PUNCT
admet-942	1004	1	drug	drug	NOUN
admet-942	1004	2	discovery	discovery	PROPN
admet-942	1004	3	today	today	NOUN
admet-942	1004	4	00	00	NUM
admet-942	1004	5	(	(	PUNCT
admet-942	1004	6	2020	2020	NUM
admet-942	1004	7	)	)	PUNCT
admet-942	1004	8	.	.	PUNCT
admet-942	1005	1	https://doi.org/10.1016/j.drudis.2020.03.002	https://doi.org/10.1016/j.drudis.2020.03.002	NOUN
admet-942	1005	2	.	.	PUNCT
admet-942	1005	3	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	1005	4	https://doi.org/10.3390/bioengineering5010024	https://doi.org/10.3390/bioengineering5010024	VERB
admet-942	1005	5	https://doi.org/10.3748/wjg.v23.i2.204	https://doi.org/10.3748/wjg.v23.i2.204	VERB
admet-942	1005	6	https://doi.org/10.1016/j.tiv.2018.08.014	https://doi.org/10.1016/j.tiv.2018.08.014	ADJ
admet-942	1005	7	https://doi.org/10.1016/j.placenta.2019.06.195	https://doi.org/10.1016/j.placenta.2019.06.195	PROPN
admet-942	1005	8	https://doi.org/10.1016/j.jtos.2020.11.004	https://doi.org/10.1016/j.jtos.2020.11.004	PROPN
admet-942	1005	9	https://doi.org/10.1016/j.vascn.2012.04.001	https://doi.org/10.1016/j.vascn.2012.04.001	NOUN
admet-942	1005	10	https://doi.org/10.1016/j.bioactmat.2020.07.016	https://doi.org/10.1016/j.bioactmat.2020.07.016	PROPN
admet-942	1005	11	https://doi.org/10.1016/j.aca.2018.06.038	https://doi.org/10.1016/j.aca.2018.06.038	ADJ
admet-942	1005	12	https://doi.org/10.1016/j.aca.2018.06.038	https://doi.org/10.1016/j.aca.2018.06.038	PROPN
admet-942	1005	13	https://doi.org/10.1016/j.tranon.2020.100959	https://doi.org/10.1016/j.tranon.2020.100959	PROPN
admet-942	1005	14	https://doi.org/10.1016/j.bej.2020.107783	https://doi.org/10.1016/j.bej.2020.107783	PROPN
admet-942	1005	15	https://doi.org/10.1016/j.bej.2020.107783	https://doi.org/10.1016/j.bej.2020.107783	PROPN
admet-942	1005	16	https://doi.org/10.1016/j.drudis.2020.03.002	https://doi.org/10.1016/j.drudis.2020.03.002	PROPN
admet-942	1005	17	r.	r.	PROPN
admet-942	1005	18	vargas	vargas	PROPN
admet-942	1005	19	,	,	PUNCT
admet-942	1005	20	a.	a.	NOUN
admet-942	1005	21	egurbide	egurbide	NOUN
admet-942	1005	22	-	-	PUNCT
admet-942	1005	23	sifre	sifre	NOUN
admet-942	1005	24	and	and	CCONJ
admet-942	1005	25	l.	l.	PROPN
admet-942	1005	26	medina	medina	PROPN
admet-942	1005	27	admet	admet	PROPN
admet-942	1005	28	&	&	CCONJ
admet-942	1005	29	dmpk	dmpk	PROPN
admet-942	1005	30	9(2	9(2	NUM
admet-942	1005	31	)	)	PUNCT
admet-942	1005	32	(	(	PUNCT
admet-942	1005	33	2021	2021	NUM
admet-942	1005	34	)	)	PUNCT
admet-942	1005	35	111	111	NUM
admet-942	1005	36	-	-	SYM
admet-942	1005	37	141	141	NUM
admet-942	1005	38	140	140	NUM
admet-942	1005	39	[	[	X
admet-942	1005	40	123	123	NUM
admet-942	1005	41	]	]	PUNCT
admet-942	1005	42	k.-h	k.-h	NOUN
admet-942	1005	43	.	.	PUNCT
admet-942	1006	1	tu	tu	PROPN
admet-942	1006	2	,	,	PUNCT
admet-942	1006	3	l.-s	l.-s	PROPN
admet-942	1006	4	.	.	PUNCT
admet-942	1007	1	yu	yu	PROPN
admet-942	1007	2	,	,	PUNCT
admet-942	1007	3	z.-h	z.-h	NOUN
admet-942	1007	4	.	.	PUNCT
admet-942	1008	1	sie	sie	PROPN
admet-942	1008	2	,	,	PUNCT
admet-942	1008	3	h.-y	h.-y	NOUN
admet-942	1008	4	.	.	PUNCT
admet-942	1009	1	hsu	hsu	PROPN
admet-942	1009	2	,	,	PUNCT
admet-942	1009	3	k.t	k.t	PROPN
admet-942	1009	4	.	.	PROPN
admet-942	1009	5	al	al	PROPN
admet-942	1009	6	-	-	PUNCT
admet-942	1009	7	jamal	jamal	PROPN
admet-942	1009	8	,	,	PUNCT
admet-942	1009	9	j.t.-w	j.t.-w	PROPN
admet-942	1009	10	.	.	PROPN
admet-942	1009	11	wang	wang	PROPN
admet-942	1009	12	,	,	PUNCT
admet-942	1009	13	y.-y	y.-y	PROPN
admet-942	1009	14	.	.	PUNCT
admet-942	1010	1	chiang	chiang	PROPN
admet-942	1010	2	.	.	PUNCT
admet-942	1011	1	development	development	NOUN
admet-942	1011	2	of	of	ADP
admet-942	1011	3	realtime	realtime	ADJ
admet-942	1011	4	transendothelial	transendothelial	ADJ
admet-942	1011	5	electrical	electrical	ADJ
admet-942	1011	6	resistance	resistance	NOUN
admet-942	1011	7	monitoring	monitoring	NOUN
admet-942	1011	8	for	for	ADP
admet-942	1011	9	an	an	DET
admet-942	1011	10	in	in	X
admet-942	1011	11	vitro	vitro	X
admet-942	1011	12	blood	blood	NOUN
admet-942	1011	13	-	-	PUNCT
admet-942	1011	14	brain	brain	NOUN
admet-942	1011	15	barrier	barrier	NOUN
admet-942	1011	16	system	system	NOUN
admet-942	1011	17	.	.	PUNCT
admet-942	1012	1	micromachines	micromachine	NOUN
admet-942	1012	2	12	12	NUM
admet-942	1012	3	(	(	PUNCT
admet-942	1012	4	2020	2020	NUM
admet-942	1012	5	)	)	PUNCT
admet-942	1012	6	37	37	NUM
admet-942	1012	7	.	.	PUNCT
admet-942	1012	8	https://doi.org/10.3390/mi12010037	https://doi.org/10.3390/mi12010037	X
admet-942	1012	9	.	.	PUNCT
admet-942	1013	1	[	[	X
admet-942	1013	2	124	124	NUM
admet-942	1013	3	]	]	X
admet-942	1013	4	b.a	b.a	PROPN
admet-942	1013	5	.	.	PROPN
admet-942	1013	6	hassell	hassell	PROPN
admet-942	1013	7	,	,	PUNCT
admet-942	1013	8	g.	g.	PROPN
admet-942	1013	9	goyal	goyal	PROPN
admet-942	1013	10	,	,	PUNCT
admet-942	1013	11	e.	e.	PROPN
admet-942	1013	12	lee	lee	PROPN
admet-942	1013	13	,	,	PUNCT
admet-942	1013	14	a.	a.	PROPN
admet-942	1013	15	sontheimer	sontheimer	PROPN
admet-942	1013	16	-	-	PUNCT
admet-942	1013	17	phelps	phelps	PROPN
admet-942	1013	18	,	,	PUNCT
admet-942	1013	19	o.	o.	PROPN
admet-942	1013	20	levy	levy	PROPN
admet-942	1013	21	,	,	PUNCT
admet-942	1013	22	c.s	c.s	PROPN
admet-942	1013	23	.	.	PROPN
admet-942	1013	24	chen	chen	PROPN
admet-942	1013	25	,	,	PUNCT
admet-942	1013	26	d.e	d.e	PROPN
admet-942	1013	27	.	.	PROPN
admet-942	1013	28	ingber	ingber	PROPN
admet-942	1013	29	.	.	PUNCT
admet-942	1014	1	human	human	ADJ
admet-942	1014	2	organ	organ	NOUN
admet-942	1014	3	chip	chip	NOUN
admet-942	1014	4	models	model	NOUN
admet-942	1014	5	recapitulate	recapitulate	VERB
admet-942	1014	6	orthotopic	orthotopic	ADJ
admet-942	1014	7	lung	lung	NOUN
admet-942	1014	8	cancer	cancer	NOUN
admet-942	1014	9	growth	growth	NOUN
admet-942	1014	10	,	,	PUNCT
admet-942	1014	11	therapeutic	therapeutic	ADJ
admet-942	1014	12	responses	response	NOUN
admet-942	1014	13	,	,	PUNCT
admet-942	1014	14	and	and	CCONJ
admet-942	1014	15	tumor	tumor	NOUN
admet-942	1014	16	dormancy	dormancy	NOUN
admet-942	1014	17	in	in	ADP
admet-942	1014	18	vitro	vitro	X
admet-942	1014	19	.	.	PUNCT
admet-942	1015	1	cell	cell	NOUN
admet-942	1015	2	reports	report	VERB
admet-942	1015	3	21	21	NUM
admet-942	1015	4	(	(	PUNCT
admet-942	1015	5	2017	2017	NUM
admet-942	1015	6	)	)	PUNCT
admet-942	1015	7	508	508	NUM
admet-942	1015	8	-	-	SYM
admet-942	1015	9	516	516	NUM
admet-942	1015	10	.	.	PUNCT
admet-942	1016	1	https://doi.org/10.1016/j.celrep.2017.09.043	https://doi.org/10.1016/j.celrep.2017.09.043	NOUN
admet-942	1016	2	.	.	PUNCT
admet-942	1017	1	[	[	X
admet-942	1017	2	125	125	NUM
admet-942	1017	3	]	]	X
admet-942	1017	4	d.h.t	d.h.t	NOUN
admet-942	1017	5	.	.	PUNCT
admet-942	1017	6	nguyen	nguyen	PROPN
admet-942	1017	7	,	,	PUNCT
admet-942	1017	8	e.	e.	PROPN
admet-942	1017	9	lee	lee	PROPN
admet-942	1017	10	,	,	PUNCT
admet-942	1017	11	s.	s.	PROPN
admet-942	1017	12	alimperti	alimperti	PROPN
admet-942	1017	13	,	,	PUNCT
admet-942	1017	14	r.j	r.j	PROPN
admet-942	1017	15	.	.	PROPN
admet-942	1017	16	norgard	norgard	PROPN
admet-942	1017	17	,	,	PUNCT
admet-942	1017	18	a.	a.	PROPN
admet-942	1017	19	wong	wong	PROPN
admet-942	1017	20	,	,	PUNCT
admet-942	1017	21	j.j.k	j.j.k	PROPN
admet-942	1017	22	.	.	PROPN
admet-942	1017	23	lee	lee	PROPN
admet-942	1017	24	,	,	PUNCT
admet-942	1017	25	j.	j.	PROPN
admet-942	1017	26	eyckmans	eyckmans	PROPN
admet-942	1017	27	,	,	PUNCT
admet-942	1017	28	b.z	b.z	PROPN
admet-942	1017	29	.	.	PROPN
admet-942	1017	30	stanger	stanger	PROPN
admet-942	1017	31	,	,	PUNCT
admet-942	1017	32	c.s	c.s	PROPN
admet-942	1017	33	.	.	PROPN
admet-942	1017	34	chen	chen	PROPN
admet-942	1017	35	.	.	PUNCT
admet-942	1018	1	a	a	DET
admet-942	1018	2	biomimetic	biomimetic	ADJ
admet-942	1018	3	pancreatic	pancreatic	ADJ
admet-942	1018	4	cancer	cancer	NOUN
admet-942	1018	5	on	on	ADP
admet-942	1018	6	-	-	PUNCT
admet-942	1018	7	chip	chip	NOUN
admet-942	1018	8	reveals	reveal	VERB
admet-942	1018	9	endothelial	endothelial	ADJ
admet-942	1018	10	ablation	ablation	NOUN
admet-942	1018	11	via	via	ADP
admet-942	1018	12	alk7	alk7	NOUN
admet-942	1018	13	signaling	signal	VERB
admet-942	1018	14	.	.	PUNCT
admet-942	1019	1	science	science	NOUN
admet-942	1019	2	advances	advance	VERB
admet-942	1019	3	5	5	NUM
admet-942	1019	4	(	(	PUNCT
admet-942	1019	5	2019	2019	NUM
admet-942	1019	6	)	)	PUNCT
admet-942	1019	7	6789	6789	NUM
admet-942	1019	8	-	-	SYM
admet-942	1019	9	6817	6817	NUM
admet-942	1019	10	.	.	PUNCT
admet-942	1020	1	https://doi.org/10.1126/sciadv.aav6789	https://doi.org/10.1126/sciadv.aav6789	ADV
admet-942	1020	2	.	.	PUNCT
admet-942	1021	1	[	[	X
admet-942	1021	2	126	126	NUM
admet-942	1021	3	]	]	X
admet-942	1021	4	s.	s.	PROPN
admet-942	1021	5	shuford	shuford	PROPN
admet-942	1021	6	,	,	PUNCT
admet-942	1021	7	c.	c.	PROPN
admet-942	1021	8	wilhelm	wilhelm	PROPN
admet-942	1021	9	,	,	PUNCT
admet-942	1021	10	m.	m.	NOUN
admet-942	1021	11	rayner	rayner	PROPN
admet-942	1021	12	,	,	PUNCT
admet-942	1021	13	a.	a.	NOUN
admet-942	1021	14	elrod	elrod	PROPN
admet-942	1021	15	,	,	PUNCT
admet-942	1021	16	m.	m.	PROPN
admet-942	1021	17	millard	millard	PROPN
admet-942	1021	18	,	,	PUNCT
admet-942	1021	19	c.	c.	PROPN
admet-942	1021	20	mattingly	mattingly	PROPN
admet-942	1021	21	,	,	PUNCT
admet-942	1021	22	a.	a.	PROPN
admet-942	1021	23	lotstein	lotstein	PROPN
admet-942	1021	24	,	,	PUNCT
admet-942	1021	25	a.m.	a.m.	PROPN
admet-942	1021	26	smith	smith	PROPN
admet-942	1021	27	,	,	PUNCT
admet-942	1021	28	q.j	q.j	PROPN
admet-942	1021	29	.	.	PROPN
admet-942	1021	30	guo	guo	PROPN
admet-942	1021	31	,	,	PUNCT
admet-942	1021	32	l.	l.	PROPN
admet-942	1021	33	o’donnell	o’donnell	PROPN
admet-942	1021	34	,	,	PUNCT
admet-942	1021	35	j.	j.	PROPN
admet-942	1021	36	elder	elder	PROPN
admet-942	1021	37	,	,	PUNCT
admet-942	1021	38	l.	l.	PROPN
admet-942	1021	39	puls	puls	PROPN
admet-942	1021	40	,	,	PUNCT
admet-942	1021	41	s.j	s.j	PROPN
admet-942	1021	42	.	.	PROPN
admet-942	1021	43	weroha	weroha	PROPN
admet-942	1021	44	,	,	PUNCT
admet-942	1021	45	x.	x.	PROPN
admet-942	1021	46	hou	hou	PROPN
admet-942	1021	47	,	,	PUNCT
admet-942	1021	48	v.	v.	PROPN
admet-942	1021	49	zanfagnin	zanfagnin	PROPN
admet-942	1021	50	,	,	PUNCT
admet-942	1021	51	a.	a.	PROPN
admet-942	1021	52	nick	nick	PROPN
admet-942	1021	53	,	,	PUNCT
admet-942	1021	54	m.p	m.p	PROPN
admet-942	1021	55	.	.	PROPN
admet-942	1021	56	stany	stany	PROPN
admet-942	1021	57	,	,	PUNCT
admet-942	1021	58	g.l	g.l	PROPN
admet-942	1021	59	.	.	PROPN
admet-942	1021	60	maxwell	maxwell	PROPN
admet-942	1021	61	,	,	PUNCT
admet-942	1021	62	t.	t.	PROPN
admet-942	1021	63	conrads	conrads	PROPN
admet-942	1021	64	,	,	PUNCT
admet-942	1021	65	a.k	a.k	PROPN
admet-942	1021	66	.	.	PROPN
admet-942	1021	67	sood	sood	PROPN
admet-942	1021	68	,	,	PUNCT
admet-942	1021	69	d.	d.	PROPN
admet-942	1021	70	orr	orr	PROPN
admet-942	1021	71	,	,	PUNCT
admet-942	1021	72	l.m	l.m	PROPN
admet-942	1021	73	.	.	PROPN
admet-942	1021	74	holmes	holmes	PROPN
admet-942	1021	75	,	,	PUNCT
admet-942	1021	76	m.	m.	NOUN
admet-942	1021	77	gevaert	gevaert	PROPN
admet-942	1021	78	,	,	PUNCT
admet-942	1021	79	h.e	h.e	PROPN
admet-942	1021	80	.	.	PROPN
admet-942	1021	81	crosswell	crosswell	PROPN
admet-942	1021	82	,	,	PUNCT
admet-942	1021	83	t.m	t.m	PROPN
admet-942	1021	84	.	.	PROPN
admet-942	1021	85	desrochers	desrochers	PROPN
admet-942	1021	86	.	.	PUNCT
admet-942	1022	1	prospective	prospective	ADJ
admet-942	1022	2	validation	validation	NOUN
admet-942	1022	3	of	of	ADP
admet-942	1022	4	an	an	DET
admet-942	1022	5	ex	ex	X
admet-942	1022	6	vivo	vivo	NOUN
admet-942	1022	7	,	,	PUNCT
admet-942	1022	8	patient	patient	NOUN
admet-942	1022	9	-	-	PUNCT
admet-942	1022	10	derived	derive	VERB
admet-942	1022	11	3d	3d	NOUN
admet-942	1022	12	spheroid	spheroid	NOUN
admet-942	1022	13	model	model	NOUN
admet-942	1022	14	for	for	ADP
admet-942	1022	15	response	response	NOUN
admet-942	1022	16	predictions	prediction	NOUN
admet-942	1022	17	in	in	ADP
admet-942	1022	18	newly	newly	ADV
admet-942	1022	19	diagnosed	diagnose	VERB
admet-942	1022	20	ovarian	ovarian	ADJ
admet-942	1022	21	cancer	cancer	NOUN
admet-942	1022	22	.	.	PUNCT
admet-942	1023	1	scientific	scientific	ADJ
admet-942	1023	2	reports	report	NOUN
admet-942	1023	3	9	9	NUM
admet-942	1023	4	(	(	PUNCT
admet-942	1023	5	2019	2019	NUM
admet-942	1023	6	)	)	PUNCT
admet-942	1023	7	1	1	NUM
admet-942	1023	8	-	-	SYM
admet-942	1023	9	13	13	NUM
admet-942	1023	10	.	.	PUNCT
admet-942	1024	1	https://doi.org/10.1038/s41598019-47578-7	https://doi.org/10.1038/s41598019-47578-7	NOUN
admet-942	1024	2	.	.	PUNCT
admet-942	1025	1	[	[	X
admet-942	1025	2	127	127	NUM
admet-942	1025	3	]	]	X
admet-942	1025	4	y.	y.	NOUN
admet-942	1025	5	choi	choi	PROPN
admet-942	1025	6	,	,	PUNCT
admet-942	1025	7	e.	e.	PROPN
admet-942	1025	8	hyun	hyun	PROPN
admet-942	1025	9	,	,	PUNCT
admet-942	1025	10	j.	j.	PROPN
admet-942	1025	11	seo	seo	PROPN
admet-942	1025	12	,	,	PUNCT
admet-942	1025	13	c.	c.	PROPN
admet-942	1025	14	blundell	blundell	PROPN
admet-942	1025	15	,	,	PUNCT
admet-942	1025	16	h.c	h.c	PROPN
admet-942	1025	17	.	.	PUNCT
admet-942	1025	18	kim	kim	PROPN
admet-942	1025	19	,	,	PUNCT
admet-942	1025	20	e.	e.	PROPN
admet-942	1025	21	lee	lee	PROPN
admet-942	1025	22	,	,	PUNCT
admet-942	1025	23	s.h	s.h	PROPN
admet-942	1025	24	.	.	PROPN
admet-942	1025	25	lee	lee	PROPN
admet-942	1025	26	,	,	PUNCT
admet-942	1025	27	a.	a.	PROPN
admet-942	1025	28	moon	moon	PROPN
admet-942	1025	29	,	,	PUNCT
admet-942	1025	30	w.k	w.k	PROPN
admet-942	1025	31	.	.	PROPN
admet-942	1025	32	moon	moon	PROPN
admet-942	1025	33	,	,	PUNCT
admet-942	1025	34	d.	d.	PROPN
admet-942	1025	35	huh	huh	INTJ
admet-942	1025	36	.	.	PUNCT
admet-942	1026	1	a	a	DET
admet-942	1026	2	microengineered	microengineere	VERB
admet-942	1026	3	pathophysiological	pathophysiological	ADJ
admet-942	1026	4	model	model	NOUN
admet-942	1026	5	of	of	ADP
admet-942	1026	6	early	early	ADJ
admet-942	1026	7	-	-	PUNCT
admet-942	1026	8	stage	stage	NOUN
admet-942	1026	9	breast	breast	NOUN
admet-942	1026	10	cancer	cancer	NOUN
admet-942	1026	11	.	.	PUNCT
admet-942	1027	1	lab	lab	NOUN
admet-942	1027	2	on	on	ADP
admet-942	1027	3	a	a	DET
admet-942	1027	4	chip	chip	NOUN
admet-942	1027	5	15	15	NUM
admet-942	1027	6	(	(	PUNCT
admet-942	1027	7	2015	2015	NUM
admet-942	1027	8	)	)	PUNCT
admet-942	1027	9	3350	3350	NUM
admet-942	1027	10	-	-	SYM
admet-942	1027	11	3357	3357	NUM
admet-942	1027	12	.	.	PUNCT
admet-942	1028	1	https://doi.org/10.1039/c5lc00514k	https://doi.org/10.1039/c5lc00514k	X
admet-942	1028	2	.	.	PUNCT
admet-942	1029	1	[	[	X
admet-942	1029	2	128	128	NUM
admet-942	1029	3	]	]	X
admet-942	1029	4	d.	d.	PROPN
admet-942	1029	5	irimia	irimia	PROPN
admet-942	1029	6	,	,	PUNCT
admet-942	1029	7	x.	x.	PROPN
admet-942	1029	8	wang	wang	PROPN
admet-942	1029	9	.	.	PUNCT
admet-942	1030	1	inflammation	inflammation	NOUN
admet-942	1030	2	-	-	PUNCT
admet-942	1030	3	on	on	ADP
admet-942	1030	4	-	-	PUNCT
admet-942	1030	5	a	a	DET
admet-942	1030	6	-	-	PUNCT
admet-942	1030	7	chip	chip	NOUN
admet-942	1030	8	:	:	PUNCT
admet-942	1030	9	probing	probe	VERB
admet-942	1030	10	the	the	DET
admet-942	1030	11	immune	immune	ADJ
admet-942	1030	12	system	system	NOUN
admet-942	1030	13	ex	ex	X
admet-942	1030	14	vivo	vivo	NOUN
admet-942	1030	15	.	.	PUNCT
admet-942	1031	1	trends	trend	NOUN
admet-942	1031	2	in	in	ADP
admet-942	1031	3	biotechnology	biotechnology	NOUN
admet-942	1031	4	36	36	NUM
admet-942	1031	5	(	(	PUNCT
admet-942	1031	6	2018	2018	NUM
admet-942	1031	7	)	)	PUNCT
admet-942	1031	8	923	923	NUM
admet-942	1031	9	-	-	SYM
admet-942	1031	10	937	937	NUM
admet-942	1031	11	.	.	PUNCT
admet-942	1032	1	https://doi.org/10.1016/j.tibtech.2018.03.011	https://doi.org/10.1016/j.tibtech.2018.03.011	X
admet-942	1032	2	.	.	PUNCT
admet-942	1033	1	[	[	X
admet-942	1033	2	129	129	NUM
admet-942	1033	3	]	]	PUNCT
admet-942	1033	4	f.	f.	PROPN
admet-942	1033	5	sharifi	sharifi	PROPN
admet-942	1033	6	,	,	PUNCT
admet-942	1033	7	s.s	s.s	PROPN
admet-942	1033	8	.	.	PROPN
admet-942	1033	9	htwe	htwe	PROPN
admet-942	1033	10	,	,	PUNCT
admet-942	1033	11	m.	m.	NOUN
admet-942	1033	12	righi	righi	PROPN
admet-942	1033	13	,	,	PUNCT
admet-942	1033	14	h.	h.	PROPN
admet-942	1033	15	liu	liu	PROPN
admet-942	1033	16	,	,	PUNCT
admet-942	1033	17	a.	a.	NOUN
admet-942	1033	18	pietralunga	pietralunga	NOUN
admet-942	1033	19	,	,	PUNCT
admet-942	1033	20	o.	o.	PROPN
admet-942	1033	21	yesil	yesil	NOUN
admet-942	1033	22	-	-	PUNCT
admet-942	1033	23	celiktas	celikta	NOUN
admet-942	1033	24	,	,	PUNCT
admet-942	1033	25	s.	s.	PROPN
admet-942	1033	26	maharjan	maharjan	PROPN
admet-942	1033	27	,	,	PUNCT
admet-942	1033	28	b.-h	b.-h	NOUN
admet-942	1033	29	.	.	PUNCT
admet-942	1034	1	cha	cha	PROPN
admet-942	1034	2	,	,	PUNCT
admet-942	1034	3	s.r	s.r	PROPN
admet-942	1034	4	.	.	PROPN
admet-942	1034	5	shin	shin	PROPN
admet-942	1034	6	,	,	PUNCT
admet-942	1034	7	m.r	m.r	PROPN
admet-942	1034	8	.	.	PROPN
admet-942	1034	9	dokmeci	dokmeci	PROPN
admet-942	1034	10	,	,	PUNCT
admet-942	1034	11	n.e	n.e	PROPN
admet-942	1034	12	.	.	PROPN
admet-942	1034	13	vrana	vrana	PROPN
admet-942	1034	14	,	,	PUNCT
admet-942	1034	15	a.m.	a.m.	PROPN
admet-942	1034	16	ghaemmaghami	ghaemmaghami	PROPN
admet-942	1034	17	,	,	PUNCT
admet-942	1034	18	a.	a.	NOUN
admet-942	1034	19	khademhosseini	khademhosseini	PROPN
admet-942	1034	20	,	,	PUNCT
admet-942	1034	21	y.s	y.s	PROPN
admet-942	1034	22	.	.	PROPN
admet-942	1034	23	zhang	zhang	PROPN
admet-942	1034	24	.	.	PUNCT
admet-942	1035	1	a	a	DET
admet-942	1035	2	foreign	foreign	ADJ
admet-942	1035	3	body	body	NOUN
admet-942	1035	4	response	response	NOUN
admet-942	1035	5	-	-	PUNCT
admet-942	1035	6	on	on	ADP
admet-942	1035	7	-	-	PUNCT
admet-942	1035	8	a	a	DET
admet-942	1035	9	-	-	PUNCT
admet-942	1035	10	chip	chip	NOUN
admet-942	1035	11	platform	platform	NOUN
admet-942	1035	12	.	.	PUNCT
admet-942	1036	1	advanced	advanced	ADJ
admet-942	1036	2	healthcare	healthcare	NOUN
admet-942	1036	3	materials	material	NOUN
admet-942	1036	4	8	8	NUM
admet-942	1036	5	(	(	PUNCT
admet-942	1036	6	2019	2019	NUM
admet-942	1036	7	)	)	PUNCT
admet-942	1036	8	1801425	1801425	NUM
admet-942	1036	9	.	.	PUNCT
admet-942	1037	1	https://doi.org/10.1002/adhm.201801425	https://doi.org/10.1002/adhm.201801425	NOUN
admet-942	1037	2	.	.	PUNCT
admet-942	1038	1	[	[	X
admet-942	1038	2	130	130	NUM
admet-942	1038	3	]	]	PUNCT
admet-942	1038	4	g.	g.	PROPN
admet-942	1038	5	goyal	goyal	PROPN
admet-942	1038	6	,	,	PUNCT
admet-942	1038	7	b.	b.	PROPN
admet-942	1038	8	bausk	bausk	PROPN
admet-942	1038	9	,	,	PUNCT
admet-942	1038	10	p.	p.	NOUN
admet-942	1038	11	prabhala	prabhala	PROPN
admet-942	1038	12	,	,	PUNCT
admet-942	1038	13	l.	l.	PROPN
admet-942	1038	14	xie	xie	PROPN
admet-942	1038	15	,	,	PUNCT
admet-942	1038	16	d.	d.	PROPN
admet-942	1038	17	curran	curran	PROPN
admet-942	1038	18	,	,	PUNCT
admet-942	1038	19	j.	j.	PROPN
admet-942	1038	20	long	long	PROPN
admet-942	1038	21	,	,	PUNCT
admet-942	1038	22	l.	l.	PROPN
admet-942	1038	23	cohen	cohen	PROPN
admet-942	1038	24	,	,	PUNCT
admet-942	1038	25	o.	o.	PROPN
admet-942	1038	26	levy	levy	PROPN
admet-942	1038	27	,	,	PUNCT
admet-942	1038	28	r.	r.	PROPN
admet-942	1038	29	prantil	prantil	PROPN
admet-942	1038	30	-	-	PUNCT
admet-942	1038	31	baun	baun	NOUN
admet-942	1038	32	,	,	PUNCT
admet-942	1038	33	d.	d.	PROPN
admet-942	1038	34	walt	walt	PROPN
admet-942	1038	35	,	,	PUNCT
admet-942	1038	36	d.	d.	PROPN
admet-942	1038	37	ingber	ingber	PROPN
admet-942	1038	38	.	.	PUNCT
admet-942	1039	1	lymph	lymph	NOUN
admet-942	1039	2	node	node	VERB
admet-942	1039	3	follicle	follicle	NOUN
admet-942	1039	4	formation	formation	NOUN
admet-942	1039	5	and	and	CCONJ
admet-942	1039	6	vaccination	vaccination	NOUN
admet-942	1039	7	responses	response	NOUN
admet-942	1039	8	reconstituted	reconstitute	VERB
admet-942	1039	9	in	in	ADP
admet-942	1039	10	vitro	vitro	X
admet-942	1039	11	in	in	ADP
admet-942	1039	12	a	a	DET
admet-942	1039	13	human	human	ADJ
admet-942	1039	14	organ	organ	NOUN
admet-942	1039	15	chip	chip	NOUN
admet-942	1039	16	.	.	PUNCT
admet-942	1040	1	biorxiv	biorxiv	NOUN
admet-942	1040	2	(	(	PUNCT
admet-942	1040	3	2019	2019	NUM
admet-942	1040	4	)	)	PUNCT
admet-942	1040	5	806505	806505	NUM
admet-942	1040	6	.	.	PUNCT
admet-942	1041	1	https://doi.org/10.1101/806505	https://doi.org/10.1101/806505	X
admet-942	1041	2	.	.	PUNCT
admet-942	1042	1	[	[	X
admet-942	1042	2	131	131	NUM
admet-942	1042	3	]	]	X
admet-942	1042	4	n.	n.	NOUN
admet-942	1042	5	gopalakrishnan	gopalakrishnan	PROPN
admet-942	1042	6	,	,	PUNCT
admet-942	1042	7	r.	r.	PROPN
admet-942	1042	8	hannam	hannam	PROPN
admet-942	1042	9	,	,	PUNCT
admet-942	1042	10	g.p	g.p	PROPN
admet-942	1042	11	.	.	PROPN
admet-942	1042	12	casoni	casoni	PROPN
admet-942	1042	13	,	,	PUNCT
admet-942	1042	14	d.	d.	PROPN
admet-942	1042	15	barriet	barriet	PROPN
admet-942	1042	16	,	,	PUNCT
admet-942	1042	17	j.m	j.m	PROPN
admet-942	1042	18	.	.	PROPN
admet-942	1042	19	ribe	ribe	PROPN
admet-942	1042	20	,	,	PUNCT
admet-942	1042	21	m.	m.	NOUN
admet-942	1042	22	haug	haug	PROPN
admet-942	1042	23	,	,	PUNCT
admet-942	1042	24	halaas	halaas	PROPN
admet-942	1042	25	.	.	PUNCT
admet-942	1043	1	infection	infection	NOUN
admet-942	1043	2	and	and	CCONJ
admet-942	1043	3	immunity	immunity	NOUN
admet-942	1043	4	on	on	ADP
admet-942	1043	5	a	a	DET
admet-942	1043	6	chip	chip	NOUN
admet-942	1043	7	:	:	PUNCT
admet-942	1043	8	a	a	DET
admet-942	1043	9	compartmentalised	compartmentalised	ADJ
admet-942	1043	10	microfluidic	microfluidic	ADJ
admet-942	1043	11	platform	platform	NOUN
admet-942	1043	12	to	to	PART
admet-942	1043	13	monitor	monitor	VERB
admet-942	1043	14	immune	immune	ADJ
admet-942	1043	15	cell	cell	NOUN
admet-942	1043	16	behaviour	behaviour	NOUN
admet-942	1043	17	in	in	ADP
admet-942	1043	18	real	real	ADJ
admet-942	1043	19	time	time	NOUN
admet-942	1043	20	.	.	PUNCT
admet-942	1044	1	lab	lab	NOUN
admet-942	1044	2	on	on	ADP
admet-942	1044	3	a	a	DET
admet-942	1044	4	chip	chip	NOUN
admet-942	1044	5	15	15	NUM
admet-942	1044	6	(	(	PUNCT
admet-942	1044	7	2015	2015	NUM
admet-942	1044	8	)	)	PUNCT
admet-942	1044	9	1481	1481	NUM
admet-942	1044	10	-	-	SYM
admet-942	1044	11	1487	1487	NUM
admet-942	1044	12	.	.	PUNCT
admet-942	1045	1	https://doi.org/10.1039/c4lc01438c	https://doi.org/10.1039/c4lc01438c	PROPN
admet-942	1045	2	.	.	PUNCT
admet-942	1046	1	[	[	X
admet-942	1046	2	132	132	NUM
admet-942	1046	3	]	]	PUNCT
admet-942	1046	4	s.	s.	PROPN
admet-942	1046	5	parlato	parlato	PROPN
admet-942	1046	6	,	,	PUNCT
admet-942	1046	7	g.	g.	PROPN
admet-942	1046	8	grisanti	grisanti	PROPN
admet-942	1046	9	,	,	PUNCT
admet-942	1046	10	g.	g.	PROPN
admet-942	1046	11	sinibaldi	sinibaldi	PROPN
admet-942	1046	12	,	,	PUNCT
admet-942	1046	13	g.	g.	PROPN
admet-942	1046	14	peruzzi	peruzzi	PROPN
admet-942	1046	15	,	,	PUNCT
admet-942	1046	16	c.m	c.m	PROPN
admet-942	1046	17	.	.	PROPN
admet-942	1046	18	casciola	casciola	PROPN
admet-942	1046	19	,	,	PUNCT
admet-942	1046	20	l.	l.	PROPN
admet-942	1046	21	gabriele	gabriele	PROPN
admet-942	1046	22	.	.	PUNCT
admet-942	1047	1	tumor	tumor	NOUN
admet-942	1047	2	-	-	PUNCT
admet-942	1047	3	on	on	ADP
admet-942	1047	4	-	-	PUNCT
admet-942	1047	5	a	a	DET
admet-942	1047	6	-	-	PUNCT
admet-942	1047	7	chip	chip	NOUN
admet-942	1047	8	platforms	platform	NOUN
admet-942	1047	9	to	to	PART
admet-942	1047	10	study	study	VERB
admet-942	1047	11	cancer	cancer	NOUN
admet-942	1047	12	-	-	PUNCT
admet-942	1047	13	immune	immune	ADJ
admet-942	1047	14	system	system	NOUN
admet-942	1047	15	crosstalk	crosstalk	NOUN
admet-942	1047	16	in	in	ADP
admet-942	1047	17	the	the	DET
admet-942	1047	18	era	era	NOUN
admet-942	1047	19	of	of	ADP
admet-942	1047	20	immunotherapy	immunotherapy	NOUN
admet-942	1047	21	.	.	PUNCT
admet-942	1048	1	lab	lab	NOUN
admet-942	1048	2	on	on	ADP
admet-942	1048	3	a	a	DET
admet-942	1048	4	chip	chip	NOUN
admet-942	1048	5	21	21	NUM
admet-942	1048	6	(	(	PUNCT
admet-942	1048	7	2021	2021	NUM
admet-942	1048	8	)	)	PUNCT
admet-942	1048	9	234253	234253	NUM
admet-942	1048	10	.	.	PUNCT
admet-942	1049	1	https://doi.org/10.1039/d0lc00799d	https://doi.org/10.1039/d0lc00799d	X
admet-942	1049	2	.	.	PUNCT
admet-942	1050	1	[	[	X
admet-942	1050	2	133	133	NUM
admet-942	1050	3	]	]	PUNCT
admet-942	1050	4	s.	s.	PROPN
admet-942	1050	5	ishida	ishida	PROPN
admet-942	1050	6	.	.	PUNCT
admet-942	1051	1	organs	organ	NOUN
admet-942	1051	2	-	-	PUNCT
admet-942	1051	3	on	on	ADP
admet-942	1051	4	-	-	PUNCT
admet-942	1051	5	a	a	DET
admet-942	1051	6	-	-	PUNCT
admet-942	1051	7	chip	chip	NOUN
admet-942	1051	8	:	:	PUNCT
admet-942	1051	9	current	current	ADJ
admet-942	1051	10	applications	application	NOUN
admet-942	1051	11	and	and	CCONJ
admet-942	1051	12	consideration	consideration	NOUN
admet-942	1051	13	points	point	NOUN
admet-942	1051	14	for	for	ADP
admet-942	1051	15	in	in	ADP
admet-942	1051	16	vitro	vitro	X
admet-942	1051	17	adme	adme	NOUN
admet-942	1051	18	-	-	PUNCT
admet-942	1051	19	tox	tox	NOUN
admet-942	1051	20	studies	study	NOUN
admet-942	1051	21	.	.	PUNCT
admet-942	1052	1	drug	drug	NOUN
admet-942	1052	2	metabolism	metabolism	NOUN
admet-942	1052	3	and	and	CCONJ
admet-942	1052	4	pharmacokinetics	pharmacokinetic	NOUN
admet-942	1052	5	33	33	NUM
admet-942	1052	6	(	(	PUNCT
admet-942	1052	7	2018	2018	NUM
admet-942	1052	8	)	)	PUNCT
admet-942	1052	9	49	49	NUM
admet-942	1052	10	-	-	SYM
admet-942	1052	11	54	54	NUM
admet-942	1052	12	.	.	PUNCT
admet-942	1052	13	https://doi.org/10.1016/j.dmpk.2018.01.003	https://doi.org/10.1016/j.dmpk.2018.01.003	NOUN
admet-942	1052	14	.	.	PUNCT
admet-942	1053	1	[	[	X
admet-942	1053	2	134	134	NUM
admet-942	1053	3	]	]	PUNCT
admet-942	1053	4	i.	i.	NOUN
admet-942	1053	5	maschmeyer	maschmeyer	PROPN
admet-942	1053	6	,	,	PUNCT
admet-942	1053	7	a.k	a.k	PROPN
admet-942	1053	8	.	.	PROPN
admet-942	1053	9	lorenz	lorenz	PROPN
admet-942	1053	10	,	,	PUNCT
admet-942	1053	11	k.	k.	PROPN
admet-942	1053	12	schimek	schimek	PROPN
admet-942	1053	13	,	,	PUNCT
admet-942	1053	14	t.	t.	PROPN
admet-942	1053	15	hasenberg	hasenberg	PROPN
admet-942	1053	16	,	,	PUNCT
admet-942	1053	17	a.p	a.p	PROPN
admet-942	1053	18	.	.	PROPN
admet-942	1053	19	ramme	ramme	NOUN
admet-942	1053	20	,	,	PUNCT
admet-942	1053	21	j.	j.	PROPN
admet-942	1053	22	hübner	hübner	PROPN
admet-942	1053	23	,	,	PUNCT
admet-942	1053	24	m.	m.	NOUN
admet-942	1053	25	lindner	lindner	PROPN
admet-942	1053	26	,	,	PUNCT
admet-942	1053	27	c.	c.	PROPN
admet-942	1053	28	drewell	drewell	PROPN
admet-942	1053	29	,	,	PUNCT
admet-942	1053	30	s.	s.	PROPN
admet-942	1053	31	bauer	bauer	PROPN
admet-942	1053	32	,	,	PUNCT
admet-942	1053	33	a.	a.	PROPN
admet-942	1053	34	thomas	thomas	PROPN
admet-942	1053	35	,	,	PUNCT
admet-942	1053	36	n.s	n.s	PROPN
admet-942	1053	37	.	.	PROPN
admet-942	1053	38	sambo	sambo	PROPN
admet-942	1053	39	,	,	PUNCT
admet-942	1053	40	f.	f.	PROPN
admet-942	1053	41	sonntag	sonntag	PROPN
admet-942	1053	42	,	,	PUNCT
admet-942	1053	43	r.	r.	PROPN
admet-942	1053	44	lauster	lauster	PROPN
admet-942	1053	45	,	,	PUNCT
admet-942	1053	46	u.	u.	PROPN
admet-942	1053	47	marx	marx	PROPN
admet-942	1053	48	.	.	PUNCT
admet-942	1054	1	a	a	DET
admet-942	1054	2	four	four	NUM
admet-942	1054	3	-	-	PUNCT
admet-942	1054	4	organ	organ	NOUN
admet-942	1054	5	-	-	PUNCT
admet-942	1054	6	chip	chip	NOUN
admet-942	1054	7	for	for	ADP
admet-942	1054	8	interconnected	interconnected	ADJ
admet-942	1054	9	long	long	ADJ
admet-942	1054	10	-	-	PUNCT
admet-942	1054	11	term	term	NOUN
admet-942	1054	12	co	co	NOUN
admet-942	1054	13	-	-	NOUN
admet-942	1054	14	culture	culture	NOUN
admet-942	1054	15	of	of	ADP
admet-942	1054	16	human	human	ADJ
admet-942	1054	17	intestine	intestine	NOUN
admet-942	1054	18	,	,	PUNCT
admet-942	1054	19	liver	liver	NOUN
admet-942	1054	20	,	,	PUNCT
admet-942	1054	21	skin	skin	NOUN
admet-942	1054	22	and	and	CCONJ
admet-942	1054	23	kidney	kidney	NOUN
admet-942	1054	24	equivalents	equivalent	NOUN
admet-942	1054	25	.	.	PUNCT
admet-942	1055	1	lab	lab	NOUN
admet-942	1055	2	on	on	ADP
admet-942	1055	3	a	a	DET
admet-942	1055	4	chip	chip	NOUN
admet-942	1055	5	15	15	NUM
admet-942	1055	6	(	(	PUNCT
admet-942	1055	7	2015	2015	NUM
admet-942	1055	8	)	)	PUNCT
admet-942	1055	9	2688	2688	NUM
admet-942	1055	10	-	-	SYM
admet-942	1055	11	2699	2699	NUM
admet-942	1055	12	.	.	PUNCT
admet-942	1056	1	https://doi.org/10.1039/c5lc00392j	https://doi.org/10.1039/c5lc00392j	ADJ
admet-942	1056	2	.	.	PUNCT
admet-942	1057	1	[	[	X
admet-942	1057	2	135	135	NUM
admet-942	1057	3	]	]	PUNCT
admet-942	1057	4	a.	a.	NOUN
admet-942	1057	5	herland	herland	PROPN
admet-942	1057	6	,	,	PUNCT
admet-942	1057	7	b.m	b.m	PROPN
admet-942	1057	8	.	.	PROPN
admet-942	1057	9	maoz	maoz	PROPN
admet-942	1057	10	,	,	PUNCT
admet-942	1057	11	d.	d.	PROPN
admet-942	1057	12	das	das	PROPN
admet-942	1057	13	,	,	PUNCT
admet-942	1057	14	m.r	m.r	PROPN
admet-942	1057	15	.	.	PROPN
admet-942	1057	16	somayaji	somayaji	PROPN
admet-942	1057	17	,	,	PUNCT
admet-942	1057	18	r.	r.	PROPN
admet-942	1057	19	prantil	prantil	PROPN
admet-942	1057	20	-	-	PUNCT
admet-942	1057	21	baun	baun	NOUN
admet-942	1057	22	,	,	PUNCT
admet-942	1057	23	r.	r.	PROPN
admet-942	1057	24	novak	novak	PROPN
admet-942	1057	25	,	,	PUNCT
admet-942	1057	26	m.	m.	NOUN
admet-942	1057	27	cronce	cronce	NOUN
admet-942	1057	28	,	,	PUNCT
admet-942	1057	29	t.	t.	PROPN
admet-942	1057	30	huffstater	huffstater	PROPN
admet-942	1057	31	,	,	PUNCT
admet-942	1057	32	s.s.f	s.s.f	PROPN
admet-942	1057	33	.	.	PROPN
admet-942	1057	34	jeanty	jeanty	PROPN
admet-942	1057	35	,	,	PUNCT
admet-942	1057	36	m.	m.	PROPN
admet-942	1057	37	ingram	ingram	PROPN
admet-942	1057	38	,	,	PUNCT
admet-942	1057	39	a.	a.	NOUN
admet-942	1057	40	chalkiadaki	chalkiadaki	PROPN
admet-942	1057	41	,	,	PUNCT
admet-942	1057	42	d.	d.	PROPN
admet-942	1057	43	benson	benson	PROPN
admet-942	1057	44	chou	chou	PROPN
admet-942	1057	45	,	,	PUNCT
admet-942	1057	46	s.	s.	PROPN
admet-942	1057	47	marquez	marquez	PROPN
admet-942	1057	48	,	,	PUNCT
admet-942	1057	49	a.	a.	NOUN
admet-942	1057	50	delahanty	delahanty	PROPN
admet-942	1057	51	,	,	PUNCT
admet-942	1057	52	s.	s.	PROPN
admet-942	1057	53	jalilifiroozinezhad	jalilifiroozinezhad	PROPN
admet-942	1057	54	,	,	PUNCT
admet-942	1057	55	y.	y.	PROPN
admet-942	1057	56	milton	milton	PROPN
admet-942	1057	57	,	,	PUNCT
admet-942	1057	58	a.	a.	PROPN
admet-942	1057	59	sontheimer	sontheimer	PROPN
admet-942	1057	60	-	-	PUNCT
admet-942	1057	61	phelps	phelps	PROPN
admet-942	1057	62	,	,	PUNCT
admet-942	1057	63	b.	b.	PROPN
admet-942	1057	64	swenor	swenor	PROPN
admet-942	1057	65	,	,	PUNCT
admet-942	1057	66	o.	o.	PROPN
admet-942	1057	67	levy	levy	NOUN
admet-942	1057	68	,	,	PUNCT
admet-942	1057	69	k.k	k.k	PROPN
admet-942	1057	70	.	.	PROPN
admet-942	1057	71	parker	parker	PROPN
admet-942	1057	72	,	,	PUNCT
admet-942	1057	73	a.	a.	PROPN
admet-942	1057	74	przekwas	przekwas	PROPN
admet-942	1057	75	,	,	PUNCT
admet-942	1057	76	d.e	d.e	PROPN
admet-942	1057	77	.	.	PROPN
admet-942	1057	78	ingber	ingber	PROPN
admet-942	1057	79	.	.	PUNCT
admet-942	1058	1	quantitative	quantitative	ADJ
admet-942	1058	2	prediction	prediction	NOUN
admet-942	1058	3	of	of	ADP
admet-942	1058	4	human	human	ADJ
admet-942	1058	5	pharmacokinetic	pharmacokinetic	ADJ
admet-942	1058	6	responses	response	NOUN
admet-942	1058	7	to	to	ADP
admet-942	1058	8	drugs	drug	NOUN
admet-942	1058	9	via	via	ADP
admet-942	1058	10	fluidically	fluidically	ADV
admet-942	1058	11	coupled	couple	VERB
admet-942	1058	12	vascularized	vascularized	ADJ
admet-942	1058	13	organ	organ	NOUN
admet-942	1058	14	chips	chip	NOUN
admet-942	1058	15	.	.	PUNCT
admet-942	1059	1	nature	nature	NOUN
admet-942	1059	2	biomedical	biomedical	ADJ
admet-942	1059	3	engineering	engineering	NOUN
admet-942	1059	4	4	4	NUM
admet-942	1059	5	(	(	PUNCT
admet-942	1059	6	2020	2020	NUM
admet-942	1059	7	)	)	PUNCT
admet-942	1059	8	421	421	NUM
admet-942	1059	9	-	-	SYM
admet-942	1059	10	436	436	NUM
admet-942	1059	11	.	.	PUNCT
admet-942	1060	1	https://doi.org/10.1038/s41551-019-0498-9	https://doi.org/10.1038/s41551-019-0498-9	NOUN
admet-942	1060	2	.	.	PUNCT
admet-942	1061	1	[	[	X
admet-942	1061	2	136	136	NUM
admet-942	1061	3	]	]	PUNCT
admet-942	1061	4	b.	b.	PROPN
admet-942	1061	5	zhang	zhang	PROPN
admet-942	1061	6	,	,	PUNCT
admet-942	1061	7	m.	m.	NOUN
admet-942	1061	8	radisic	radisic	NOUN
admet-942	1061	9	.	.	PUNCT
admet-942	1062	1	organ	organ	NOUN
admet-942	1062	2	-	-	PUNCT
admet-942	1062	3	on	on	ADP
admet-942	1062	4	-	-	PUNCT
admet-942	1062	5	a	a	DET
admet-942	1062	6	-	-	PUNCT
admet-942	1062	7	chip	chip	NOUN
admet-942	1062	8	devices	device	NOUN
admet-942	1062	9	advance	advance	VERB
admet-942	1062	10	to	to	ADP
admet-942	1062	11	market	market	NOUN
admet-942	1062	12	.	.	PUNCT
admet-942	1063	1	lab	lab	NOUN
admet-942	1063	2	on	on	ADP
admet-942	1063	3	a	a	DET
admet-942	1063	4	chip	chip	NOUN
admet-942	1063	5	17	17	NUM
admet-942	1063	6	(	(	PUNCT
admet-942	1063	7	2017	2017	NUM
admet-942	1063	8	)	)	PUNCT
admet-942	1063	9	23952420	23952420	NUM
admet-942	1063	10	.	.	PUNCT
admet-942	1064	1	https://doi.org/10.1039/c6lc01554a	https://doi.org/10.1039/c6lc01554a	NOUN
admet-942	1064	2	.	.	PUNCT
admet-942	1065	1	[	[	X
admet-942	1065	2	137	137	NUM
admet-942	1065	3	]	]	PUNCT
admet-942	1065	4	q.	q.	PROPN
admet-942	1065	5	ramadan	ramadan	PROPN
admet-942	1065	6	,	,	PUNCT
admet-942	1065	7	m.	m.	NOUN
admet-942	1065	8	zourob	zourob	PROPN
admet-942	1065	9	.	.	PUNCT
admet-942	1065	10	organ	organ	PROPN
admet-942	1065	11	-	-	PUNCT
admet-942	1065	12	on	on	ADP
admet-942	1065	13	-	-	PUNCT
admet-942	1065	14	a	a	DET
admet-942	1065	15	-	-	PUNCT
admet-942	1065	16	chip	chip	NOUN
admet-942	1065	17	engineering	engineering	NOUN
admet-942	1065	18	:	:	PUNCT
admet-942	1065	19	toward	toward	ADP
admet-942	1065	20	bridging	bridge	VERB
admet-942	1065	21	the	the	DET
admet-942	1065	22	gap	gap	NOUN
admet-942	1065	23	between	between	ADP
admet-942	1065	24	lab	lab	NOUN
admet-942	1065	25	and	and	CCONJ
admet-942	1065	26	industry	industry	NOUN
admet-942	1065	27	.	.	PUNCT
admet-942	1066	1	biomicrofluidics	biomicrofluidic	NOUN
admet-942	1066	2	14	14	NUM
admet-942	1066	3	(	(	PUNCT
admet-942	1066	4	2020	2020	NUM
admet-942	1066	5	)	)	PUNCT
admet-942	1066	6	.	.	PUNCT
admet-942	1067	1	https://doi.org/10.1063/5.0011583	https://doi.org/10.1063/5.0011583	NOUN
admet-942	1067	2	.	.	PUNCT
admet-942	1068	1	https://doi.org/10.3390/mi12010037	https://doi.org/10.3390/mi12010037	PROPN
admet-942	1068	2	https://doi.org/10.1016/j.celrep.2017.09.043	https://doi.org/10.1016/j.celrep.2017.09.043	PROPN
admet-942	1068	3	https://doi.org/10.1126/sciadv.aav6789	https://doi.org/10.1126/sciadv.aav6789	NOUN
admet-942	1068	4	https://doi.org/10.1038/s41598-019-47578-7	https://doi.org/10.1038/s41598-019-47578-7	NUM
admet-942	1068	5	https://doi.org/10.1038/s41598-019-47578-7	https://doi.org/10.1038/s41598-019-47578-7	NUM
admet-942	1068	6	https://doi.org/10.1039/c5lc00514k	https://doi.org/10.1039/c5lc00514k	NOUN
admet-942	1068	7	https://doi.org/10.1016/j.tibtech.2018.03.011	https://doi.org/10.1016/j.tibtech.2018.03.011	NUM
admet-942	1068	8	https://doi.org/10.1101/806505	https://doi.org/10.1101/806505	ADP
admet-942	1068	9	https://doi.org/10.1039/c4lc01438c	https://doi.org/10.1039/c4lc01438c	PROPN
admet-942	1068	10	https://doi.org/10.1039/d0lc00799d	https://doi.org/10.1039/d0lc00799d	PROPN
admet-942	1068	11	https://doi.org/10.1039/c5lc00392j	https://doi.org/10.1039/c5lc00392j	ADP
admet-942	1068	12	https://doi.org/10.1038/s41551-019-0498-9	https://doi.org/10.1038/s41551-019-0498-9	NUM
admet-942	1068	13	https://doi.org/10.1038/s41551-019-0498-9	https://doi.org/10.1038/s41551-019-0498-9	NUM
admet-942	1068	14	https://doi.org/10.1039/c6lc01554a	https://doi.org/10.1039/c6lc01554a	NOUN
admet-942	1068	15	https://doi.org/10.1063/5.0011583	https://doi.org/10.1063/5.0011583	PROPN
admet-942	1068	16	admet	admet	PROPN
admet-942	1068	17	&	&	CCONJ
admet-942	1068	18	dmpk	dmpk	PROPN
admet-942	1068	19	9(2	9(2	NUM
admet-942	1068	20	)	)	PUNCT
admet-942	1068	21	(	(	PUNCT
admet-942	1068	22	2021	2021	NUM
admet-942	1068	23	)	)	PUNCT
admet-942	1068	24	111	111	NUM
admet-942	1068	25	-	-	SYM
admet-942	1068	26	141	141	NUM
admet-942	1068	27	organ	organ	NOUN
admet-942	1068	28	-	-	PUNCT
admet-942	1068	29	on	on	ADP
admet-942	1068	30	-	-	PUNCT
admet-942	1068	31	a	a	DET
admet-942	1068	32	-	-	PUNCT
admet-942	1068	33	chip	chip	NOUN
admet-942	1068	34	systems	system	NOUN
admet-942	1068	35	for	for	ADP
admet-942	1068	36	new	new	ADJ
admet-942	1068	37	drugs	drug	NOUN
admet-942	1068	38	development	development	NOUN
admet-942	1068	39	doi	doi	PROPN
admet-942	1068	40	:	:	PUNCT
admet-942	1068	41	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	NOUN
admet-942	1068	42	141	141	NUM
admet-942	1068	43	[	[	SYM
admet-942	1068	44	138	138	NUM
admet-942	1068	45	]	]	X
admet-942	1068	46	e.m	e.m	PROPN
admet-942	1068	47	.	.	PROPN
admet-942	1068	48	dehne	dehne	PROPN
admet-942	1068	49	,	,	PUNCT
admet-942	1068	50	h.	h.	PROPN
admet-942	1068	51	erfurth	erfurth	PROPN
admet-942	1068	52	,	,	PUNCT
admet-942	1068	53	a.k	a.k	PROPN
admet-942	1068	54	.	.	PROPN
admet-942	1068	55	muhsmann	muhsmann	PROPN
admet-942	1068	56	,	,	PUNCT
admet-942	1068	57	u.	u.	PROPN
admet-942	1068	58	marx	marx	PROPN
admet-942	1068	59	.	.	PUNCT
admet-942	1068	60	automation	automation	NOUN
admet-942	1068	61	and	and	CCONJ
admet-942	1068	62	opportunities	opportunity	NOUN
admet-942	1068	63	for	for	ADP
admet-942	1068	64	industry	industry	NOUN
admet-942	1068	65	scale	scale	NOUN
admet-942	1068	66	-	-	PUNCT
admet-942	1068	67	up	up	NOUN
admet-942	1068	68	of	of	ADP
admet-942	1068	69	microphysiological	microphysiological	ADJ
admet-942	1068	70	systems	system	NOUN
admet-942	1068	71	.	.	PUNCT
admet-942	1069	1	en	en	ADJ
admet-942	1069	2	:	:	PUNCT
admet-942	1069	3	organ	organ	NOUN
admet-942	1069	4	-	-	PUNCT
admet-942	1069	5	on	on	ADP
admet-942	1069	6	-	-	PUNCT
admet-942	1069	7	a	a	DET
admet-942	1069	8	-	-	PUNCT
admet-942	1069	9	chip	chip	NOUN
admet-942	1069	10	eng	eng	PROPN
admet-942	1069	11	.	.	PROPN
admet-942	1069	12	microenviron	microenviron	PROPN
admet-942	1069	13	.	.	PUNCT
admet-942	1070	1	saf	saf	PROPN
admet-942	1070	2	.	.	PROPN
admet-942	1070	3	effic	effic	PROPN
admet-942	1070	4	.	.	PUNCT
admet-942	1071	1	test	test	NOUN
admet-942	1071	2	.	.	PUNCT
admet-942	1072	1	,	,	PUNCT
admet-942	1072	2	elsevier	elsevier	NOUN
admet-942	1072	3	,	,	PUNCT
admet-942	1072	4	2019	2019	NUM
admet-942	1072	5	:	:	PUNCT
admet-942	1073	1	pp	pp	ADJ
admet-942	1073	2	.	.	PUNCT
admet-942	1074	1	441	441	NUM
admet-942	1074	2	-	-	SYM
admet-942	1074	3	462	462	NUM
admet-942	1074	4	.	.	PUNCT
admet-942	1075	1	https://doi.org/10.1016/b978-0-12-817202-5.00014-0	https://doi.org/10.1016/b978-0-12-817202-5.00014-0	VERB
admet-942	1075	2	.	.	PUNCT
admet-942	1076	1	[	[	X
admet-942	1076	2	139	139	NUM
admet-942	1076	3	]	]	X
admet-942	1076	4	a.r	a.r	PROPN
admet-942	1076	5	.	.	PROPN
admet-942	1076	6	perestrelo	perestrelo	PROPN
admet-942	1076	7	,	,	PUNCT
admet-942	1076	8	a.c.p	a.c.p	PROPN
admet-942	1076	9	.	.	PUNCT
admet-942	1076	10	águas	águas	PROPN
admet-942	1076	11	,	,	PUNCT
admet-942	1076	12	a.	a.	NOUN
admet-942	1076	13	rainer	rainer	PROPN
admet-942	1076	14	,	,	PUNCT
admet-942	1076	15	g.	g.	PROPN
admet-942	1076	16	forte	forte	PROPN
admet-942	1076	17	.	.	PUNCT
admet-942	1076	18	microfluidic	microfluidic	ADJ
admet-942	1076	19	organ	organ	NOUN
admet-942	1076	20	/	/	SYM
admet-942	1076	21	body	body	NOUN
admet-942	1076	22	-	-	PUNCT
admet-942	1076	23	on	on	ADP
admet-942	1076	24	-	-	PUNCT
admet-942	1076	25	a	a	DET
admet-942	1076	26	-	-	PUNCT
admet-942	1076	27	chip	chip	NOUN
admet-942	1076	28	devices	device	NOUN
admet-942	1076	29	at	at	ADP
admet-942	1076	30	the	the	DET
admet-942	1076	31	convergence	convergence	NOUN
admet-942	1076	32	of	of	ADP
admet-942	1076	33	biology	biology	NOUN
admet-942	1076	34	and	and	CCONJ
admet-942	1076	35	microengineering	microengineering	NOUN
admet-942	1076	36	.	.	PUNCT
admet-942	1077	1	sensors	sensor	NOUN
admet-942	1077	2	(	(	PUNCT
admet-942	1077	3	switzerland	switzerland	PROPN
admet-942	1077	4	)	)	PUNCT
admet-942	1077	5	15	15	NUM
admet-942	1077	6	(	(	PUNCT
admet-942	1077	7	2015	2015	NUM
admet-942	1077	8	)	)	PUNCT
admet-942	1077	9	31142	31142	NUM
admet-942	1077	10	-	-	SYM
admet-942	1077	11	31170	31170	NUM
admet-942	1077	12	.	.	PUNCT
admet-942	1078	1	https://doi.org/10.3390/s151229848	https://doi.org/10.3390/s151229848	NUM
admet-942	1078	2	.	.	PUNCT
admet-942	1079	1	[	[	X
admet-942	1079	2	140	140	NUM
admet-942	1079	3	]	]	PUNCT
admet-942	1079	4	j.	j.	PROPN
admet-942	1079	5	zhang	zhang	PROPN
admet-942	1079	6	,	,	PUNCT
admet-942	1079	7	x.	x.	PROPN
admet-942	1079	8	wei	wei	PROPN
admet-942	1079	9	,	,	PUNCT
admet-942	1079	10	r.	r.	PROPN
admet-942	1079	11	zeng	zeng	PROPN
admet-942	1079	12	,	,	PUNCT
admet-942	1079	13	f.	f.	PROPN
admet-942	1079	14	xu	xu	PROPN
admet-942	1079	15	,	,	PUNCT
admet-942	1079	16	x.	x.	PROPN
admet-942	1079	17	li	li	PROPN
admet-942	1079	18	.	.	PROPN
admet-942	1079	19	stem	stem	NOUN
admet-942	1079	20	cell	cell	NOUN
admet-942	1079	21	culture	culture	NOUN
admet-942	1079	22	and	and	CCONJ
admet-942	1079	23	differentiation	differentiation	NOUN
admet-942	1079	24	in	in	ADP
admet-942	1079	25	microfluidic	microfluidic	ADJ
admet-942	1079	26	devices	device	NOUN
admet-942	1079	27	toward	toward	ADP
admet-942	1079	28	organ	organ	NOUN
admet-942	1079	29	-	-	PUNCT
admet-942	1079	30	on	on	ADP
admet-942	1079	31	-	-	PUNCT
admet-942	1079	32	a	a	DET
admet-942	1079	33	-	-	PUNCT
admet-942	1079	34	chip	chip	NOUN
admet-942	1079	35	.	.	PUNCT
admet-942	1080	1	future	future	ADJ
admet-942	1080	2	science	science	NOUN
admet-942	1080	3	oa	oa	ADP
admet-942	1080	4	3	3	NUM
admet-942	1080	5	(	(	PUNCT
admet-942	1080	6	2017	2017	NUM
admet-942	1080	7	)	)	PUNCT
admet-942	1080	8	fso187	fso187	PROPN
admet-942	1080	9	.	.	PUNCT
admet-942	1081	1	https://doi.org/10.4155/fsoa-20160091	https://doi.org/10.4155/fsoa-20160091	PROPN
admet-942	1081	2	.	.	PUNCT
admet-942	1082	1	[	[	X
admet-942	1082	2	141	141	NUM
admet-942	1082	3	]	]	X
admet-942	1082	4	i.r	i.r	PROPN
admet-942	1082	5	.	.	PROPN
admet-942	1082	6	mccracken	mccracken	PROPN
admet-942	1082	7	,	,	PUNCT
admet-942	1082	8	r.s	r.s	PROPN
admet-942	1082	9	.	.	PROPN
admet-942	1082	10	taylor	taylor	PROPN
admet-942	1082	11	,	,	PUNCT
admet-942	1082	12	f.o	f.o	PROPN
admet-942	1082	13	.	.	PROPN
admet-942	1082	14	kok	kok	PROPN
admet-942	1082	15	,	,	PUNCT
admet-942	1082	16	f.	f.	PROPN
admet-942	1082	17	de	de	PROPN
admet-942	1082	18	la	la	PROPN
admet-942	1082	19	cuesta	cuesta	PROPN
admet-942	1082	20	,	,	PUNCT
admet-942	1082	21	r.	r.	PROPN
admet-942	1082	22	dobie	dobie	PROPN
admet-942	1082	23	,	,	PUNCT
admet-942	1082	24	b.e.p	b.e.p	PROPN
admet-942	1082	25	.	.	PUNCT
admet-942	1082	26	henderson	henderson	PROPN
admet-942	1082	27	,	,	PUNCT
admet-942	1082	28	j.c	j.c	PROPN
admet-942	1082	29	.	.	PROPN
admet-942	1082	30	mountford	mountford	PROPN
admet-942	1082	31	,	,	PUNCT
admet-942	1082	32	a.	a.	PROPN
admet-942	1082	33	caudrillier	caudrillier	PROPN
admet-942	1082	34	,	,	PUNCT
admet-942	1082	35	n.c	n.c	PROPN
admet-942	1082	36	.	.	PROPN
admet-942	1082	37	henderson	henderson	PROPN
admet-942	1082	38	,	,	PUNCT
admet-942	1082	39	c.p	c.p	PROPN
admet-942	1082	40	.	.	PROPN
admet-942	1082	41	ponting	ponting	NOUN
admet-942	1082	42	,	,	PUNCT
admet-942	1082	43	a.h	a.h	PROPN
admet-942	1082	44	.	.	PROPN
admet-942	1082	45	baker	baker	PROPN
admet-942	1082	46	.	.	PUNCT
admet-942	1083	1	transcriptional	transcriptional	ADJ
admet-942	1083	2	dynamics	dynamic	NOUN
admet-942	1083	3	of	of	ADP
admet-942	1083	4	pluripotent	pluripotent	ADJ
admet-942	1083	5	stemcell	stemcell	PROPN
admet-942	1083	6	-	-	PUNCT
admet-942	1083	7	derived	derive	VERB
admet-942	1083	8	endothelial	endothelial	NOUN
admet-942	1083	9	cell	cell	NOUN
admet-942	1083	10	differentiation	differentiation	NOUN
admet-942	1083	11	revealed	reveal	VERB
admet-942	1083	12	by	by	ADP
admet-942	1083	13	single	single	ADJ
admet-942	1083	14	-	-	PUNCT
admet-942	1083	15	cell	cell	NOUN
admet-942	1083	16	rna	rna	NOUN
admet-942	1083	17	sequencing	sequencing	NOUN
admet-942	1083	18	.	.	PUNCT
admet-942	1084	1	european	european	ADJ
admet-942	1084	2	heart	heart	PROPN
admet-942	1084	3	journal	journal	PROPN
admet-942	1084	4	41	41	NUM
admet-942	1084	5	(	(	PUNCT
admet-942	1084	6	2020	2020	NUM
admet-942	1084	7	)	)	PUNCT
admet-942	1084	8	1024	1024	NUM
admet-942	1084	9	-	-	SYM
admet-942	1084	10	1036	1036	NUM
admet-942	1084	11	.	.	PUNCT
admet-942	1085	1	https://doi.org/10.1093/eurheartj/ehz351	https://doi.org/10.1093/eurheartj/ehz351	NOUN
admet-942	1085	2	.	.	PUNCT
admet-942	1086	1	[	[	X
admet-942	1086	2	142	142	NUM
admet-942	1086	3	]	]	PUNCT
admet-942	1086	4	s.w	s.w	PROPN
admet-942	1086	5	.	.	PROPN
admet-942	1086	6	tang	tang	PROPN
admet-942	1086	7	,	,	PUNCT
admet-942	1086	8	w.y	w.y	PROPN
admet-942	1086	9	.	.	PUNCT
admet-942	1086	10	tong	tong	PROPN
admet-942	1086	11	,	,	PUNCT
admet-942	1086	12	s.w	s.w	PROPN
admet-942	1086	13	.	.	PROPN
admet-942	1086	14	pang	pang	PROPN
admet-942	1086	15	,	,	PUNCT
admet-942	1086	16	n.h	n.h	PROPN
admet-942	1086	17	.	.	PROPN
admet-942	1086	18	voelcker	voelcker	PROPN
admet-942	1086	19	,	,	PUNCT
admet-942	1086	20	y.w	y.w	PROPN
admet-942	1086	21	.	.	PROPN
admet-942	1086	22	lam	lam	PROPN
admet-942	1086	23	.	.	PUNCT
admet-942	1087	1	deconstructing	deconstruct	VERB
admet-942	1087	2	,	,	PUNCT
admet-942	1087	3	replicating	replicating	NOUN
admet-942	1087	4	,	,	PUNCT
admet-942	1087	5	and	and	CCONJ
admet-942	1087	6	engineering	engineer	VERB
admet-942	1087	7	tissue	tissue	NOUN
admet-942	1087	8	microenvironment	microenvironment	NOUN
admet-942	1087	9	for	for	ADP
admet-942	1087	10	stem	stem	NOUN
admet-942	1087	11	cell	cell	NOUN
admet-942	1087	12	differentiation	differentiation	NOUN
admet-942	1087	13	.	.	PUNCT
admet-942	1088	1	tissue	tissue	NOUN
admet-942	1088	2	engineering	engineering	NOUN
admet-942	1088	3	part	part	NOUN
admet-942	1088	4	b	b	NOUN
admet-942	1088	5	:	:	PUNCT
admet-942	1088	6	reviews	review	NOUN
admet-942	1088	7	00	00	PUNCT
admet-942	1088	8	(	(	PUNCT
admet-942	1088	9	2020	2020	NUM
admet-942	1088	10	)	)	PUNCT
admet-942	1088	11	.	.	PUNCT
admet-942	1089	1	https://doi.org/10.1089/ten.teb.2020.0044	https://doi.org/10.1089/ten.teb.2020.0044	X
admet-942	1089	2	.	.	PUNCT
admet-942	1090	1	[	[	X
admet-942	1090	2	143	143	NUM
admet-942	1090	3	]	]	X
admet-942	1090	4	q.	q.	PROPN
admet-942	1090	5	wu	wu	PROPN
admet-942	1090	6	,	,	PUNCT
admet-942	1090	7	j.	j.	PROPN
admet-942	1090	8	liu	liu	PROPN
admet-942	1090	9	,	,	PUNCT
admet-942	1090	10	x.	x.	PROPN
admet-942	1090	11	wang	wang	PROPN
admet-942	1090	12	,	,	PUNCT
admet-942	1090	13	l.	l.	PROPN
admet-942	1090	14	feng	feng	PROPN
admet-942	1090	15	,	,	PUNCT
admet-942	1090	16	j.	j.	PROPN
admet-942	1090	17	wu	wu	PROPN
admet-942	1090	18	,	,	PUNCT
admet-942	1090	19	x.	x.	PROPN
admet-942	1090	20	zhu	zhu	PROPN
admet-942	1090	21	,	,	PUNCT
admet-942	1090	22	w.	w.	PROPN
admet-942	1090	23	wen	wen	PROPN
admet-942	1090	24	,	,	PUNCT
admet-942	1090	25	x.	x.	PROPN
admet-942	1090	26	gong	gong	PROPN
admet-942	1090	27	.	.	PUNCT
admet-942	1091	1	organ	organ	NOUN
admet-942	1091	2	-	-	PUNCT
admet-942	1091	3	on	on	ADP
admet-942	1091	4	-	-	PUNCT
admet-942	1091	5	a	a	DET
admet-942	1091	6	-	-	PUNCT
admet-942	1091	7	chip	chip	NOUN
admet-942	1091	8	:	:	PUNCT
admet-942	1091	9	recent	recent	ADJ
admet-942	1091	10	breakthroughs	breakthrough	NOUN
admet-942	1091	11	and	and	CCONJ
admet-942	1091	12	future	future	ADJ
admet-942	1091	13	prospects	prospect	NOUN
admet-942	1091	14	.	.	PUNCT
admet-942	1092	1	biomedical	biomedical	ADJ
admet-942	1092	2	engineering	engineering	NOUN
admet-942	1092	3	online	online	ADV
admet-942	1092	4	19	19	NUM
admet-942	1092	5	(	(	PUNCT
admet-942	1092	6	2020	2020	NUM
admet-942	1092	7	)	)	PUNCT
admet-942	1092	8	1	1	NUM
admet-942	1092	9	-	-	SYM
admet-942	1092	10	19	19	NUM
admet-942	1092	11	.	.	PUNCT
admet-942	1092	12	https://doi.org/10.1186/s12938-020-0752-0	https://doi.org/10.1186/s12938-020-0752-0	NUM
admet-942	1092	13	.	.	PUNCT
admet-942	1093	1	[	[	X
admet-942	1093	2	144	144	NUM
admet-942	1093	3	]	]	X
admet-942	1093	4	h.	h.	PROPN
admet-942	1093	5	hirama	hirama	PROPN
admet-942	1093	6	,	,	PUNCT
admet-942	1093	7	t.	t.	NOUN
admet-942	1093	8	satoh	satoh	PROPN
admet-942	1093	9	,	,	PUNCT
admet-942	1093	10	s.	s.	PROPN
admet-942	1093	11	sugiura	sugiura	PROPN
admet-942	1093	12	,	,	PUNCT
admet-942	1093	13	k.	k.	PROPN
admet-942	1093	14	shin	shin	PROPN
admet-942	1093	15	,	,	PUNCT
admet-942	1093	16	r.	r.	PROPN
admet-942	1093	17	onuki	onuki	PROPN
admet-942	1093	18	-	-	PUNCT
admet-942	1093	19	nagasaki	nagasaki	PROPN
admet-942	1093	20	,	,	PUNCT
admet-942	1093	21	t.	t.	PROPN
admet-942	1093	22	kanamori	kanamori	PROPN
admet-942	1093	23	,	,	PUNCT
admet-942	1093	24	t.	t.	PROPN
admet-942	1093	25	inoue	inoue	PROPN
admet-942	1093	26	.	.	PUNCT
admet-942	1093	27	glass	glass	NOUN
admet-942	1093	28	-	-	PUNCT
admet-942	1093	29	based	base	VERB
admet-942	1093	30	organon	organon	NOUN
admet-942	1093	31	-	-	PUNCT
admet-942	1093	32	a	a	DET
admet-942	1093	33	-	-	PUNCT
admet-942	1093	34	chip	chip	NOUN
admet-942	1093	35	device	device	NOUN
admet-942	1093	36	for	for	ADP
admet-942	1093	37	restricting	restrict	VERB
admet-942	1093	38	small	small	ADJ
admet-942	1093	39	molecular	molecular	ADJ
admet-942	1093	40	absorption	absorption	NOUN
admet-942	1093	41	.	.	PUNCT
admet-942	1094	1	journal	journal	NOUN
admet-942	1094	2	of	of	ADP
admet-942	1094	3	bioscience	bioscience	NOUN
admet-942	1094	4	and	and	CCONJ
admet-942	1094	5	bioengineering	bioengineere	VERB
admet-942	1094	6	127	127	NUM
admet-942	1094	7	(	(	PUNCT
admet-942	1094	8	2019	2019	NUM
admet-942	1094	9	)	)	PUNCT
admet-942	1094	10	641	641	NUM
admet-942	1094	11	-	-	SYM
admet-942	1094	12	646	646	NUM
admet-942	1094	13	.	.	PUNCT
admet-942	1095	1	https://doi.org/10.1016/j.jbiosc.2018.10.019	https://doi.org/10.1016/j.jbiosc.2018.10.019	PROPN
admet-942	1095	2	.	.	PUNCT
admet-942	1096	1	[	[	X
admet-942	1096	2	145	145	NUM
admet-942	1096	3	]	]	PUNCT
admet-942	1096	4	a.	a.	NOUN
admet-942	1096	5	spanu	spanu	PROPN
admet-942	1096	6	,	,	PUNCT
admet-942	1096	7	l.	l.	PROPN
admet-942	1096	8	martines	martines	PROPN
admet-942	1096	9	,	,	PUNCT
admet-942	1096	10	a.	a.	PROPN
admet-942	1096	11	bonfiglio	bonfiglio	PROPN
admet-942	1096	12	.	.	PUNCT
admet-942	1097	1	interfacing	interface	VERB
admet-942	1097	2	cells	cell	NOUN
admet-942	1097	3	with	with	ADP
admet-942	1097	4	organic	organic	ADJ
admet-942	1097	5	transistors	transistor	NOUN
admet-942	1097	6	:	:	PUNCT
admet-942	1097	7	a	a	DET
admet-942	1097	8	review	review	NOUN
admet-942	1097	9	of	of	ADP
admet-942	1097	10	in	in	ADP
admet-942	1097	11	vitro	vitro	X
admet-942	1097	12	and	and	CCONJ
admet-942	1097	13	in	in	ADP
admet-942	1097	14	vivo	vivo	ADJ
admet-942	1097	15	applications	application	NOUN
admet-942	1097	16	.	.	PUNCT
admet-942	1098	1	lab	lab	NOUN
admet-942	1098	2	on	on	ADP
admet-942	1098	3	a	a	DET
admet-942	1098	4	chip	chip	NOUN
admet-942	1098	5	(	(	PUNCT
admet-942	1098	6	2021	2021	NUM
admet-942	1098	7	)	)	PUNCT
admet-942	1098	8	.	.	PUNCT
admet-942	1099	1	https://doi.org/10.1039/d0lc01007c	https://doi.org/10.1039/d0lc01007c	PROPN
admet-942	1099	2	.	.	PUNCT
admet-942	1100	1	[	[	X
admet-942	1100	2	146	146	NUM
admet-942	1100	3	]	]	X
admet-942	1100	4	y.	y.	PROPN
admet-942	1100	5	liang	liang	PROPN
admet-942	1100	6	,	,	PUNCT
admet-942	1100	7	j.-y	j.-y	PROPN
admet-942	1100	8	.	.	PUNCT
admet-942	1101	1	yoon	yoon	PROPN
admet-942	1101	2	.	.	PUNCT
admet-942	1102	1	in	in	ADP
admet-942	1102	2	situ	situ	ADJ
admet-942	1102	3	sensors	sensor	NOUN
admet-942	1102	4	for	for	ADP
admet-942	1102	5	blood	blood	NOUN
admet-942	1102	6	-	-	PUNCT
admet-942	1102	7	brain	brain	NOUN
admet-942	1102	8	barrier	barrier	NOUN
admet-942	1102	9	(	(	PUNCT
admet-942	1102	10	bbb	bbb	NOUN
admet-942	1102	11	)	)	PUNCT
admet-942	1102	12	on	on	ADP
admet-942	1102	13	a	a	DET
admet-942	1102	14	chip	chip	NOUN
admet-942	1102	15	.	.	PUNCT
admet-942	1103	1	sensors	sensor	NOUN
admet-942	1103	2	and	and	CCONJ
admet-942	1103	3	actuators	actuator	NOUN
admet-942	1103	4	reports	report	NOUN
admet-942	1103	5	(	(	PUNCT
admet-942	1103	6	2021	2021	NUM
admet-942	1103	7	)	)	PUNCT
admet-942	1103	8	100031	100031	NUM
admet-942	1103	9	.	.	PUNCT
admet-942	1104	1	https://doi.org/10.1016/j.snr.2021.100031	https://doi.org/10.1016/j.snr.2021.100031	PROPN
admet-942	1104	2	.	.	PUNCT
admet-942	1105	1	©	©	PROPN
admet-942	1105	2	2021	2021	NUM
admet-942	1105	3	by	by	ADP
admet-942	1105	4	the	the	DET
admet-942	1105	5	authors	author	NOUN
admet-942	1105	6	;	;	PUNCT
admet-942	1105	7	licensee	licensee	PROPN
admet-942	1105	8	iapc	iapc	PROPN
admet-942	1105	9	,	,	PUNCT
admet-942	1105	10	zagreb	zagreb	PROPN
admet-942	1105	11	,	,	PUNCT
admet-942	1105	12	croatia	croatia	PROPN
admet-942	1105	13	.	.	PUNCT
admet-942	1106	1	this	this	DET
admet-942	1106	2	article	article	NOUN
admet-942	1106	3	is	be	AUX
admet-942	1106	4	an	an	DET
admet-942	1106	5	open	open	ADJ
admet-942	1106	6	-	-	PUNCT
admet-942	1106	7	access	access	NOUN
admet-942	1106	8	article	article	NOUN
admet-942	1106	9	distributed	distribute	VERB
admet-942	1106	10	under	under	ADP
admet-942	1106	11	the	the	DET
admet-942	1106	12	terms	term	NOUN
admet-942	1106	13	and	and	CCONJ
admet-942	1106	14	conditions	condition	NOUN
admet-942	1106	15	of	of	ADP
admet-942	1106	16	the	the	DET
admet-942	1106	17	creative	creative	ADJ
admet-942	1106	18	commons	common	NOUN
admet-942	1106	19	attribution	attribution	NOUN
admet-942	1106	20	license(http://creativecommons.org	license(http://creativecommons.org	X
admet-942	1106	21	/	/	SYM
admet-942	1106	22	licenses	license	NOUN
admet-942	1106	23	/	/	SYM
admet-942	1106	24	by/3.0/	by/3.0/	NOUN
admet-942	1106	25	)	)	PUNCT
admet-942	1106	26	http://doi.org/10.5599/admet.942	http://doi.org/10.5599/admet.942	VERB
admet-942	1106	27	https://doi.org/10.1016/b978-0-12-817202-5.00014-0	https://doi.org/10.1016/b978-0-12-817202-5.00014-0	VERB
admet-942	1106	28	https://doi.org/10.4155/fsoa-2016-0091	https://doi.org/10.4155/fsoa-2016-0091	PROPN
admet-942	1106	29	https://doi.org/10.4155/fsoa-2016-0091	https://doi.org/10.4155/fsoa-2016-0091	PROPN
admet-942	1106	30	https://doi.org/10.1093/eurheartj/ehz351	https://doi.org/10.1093/eurheartj/ehz351	NOUN
admet-942	1106	31	https://doi.org/10.1089/ten.teb.2020.0044	https://doi.org/10.1089/ten.teb.2020.0044	PROPN
admet-942	1106	32	https://doi.org/10.1039/d0lc01007c	https://doi.org/10.1039/d0lc01007c	PROPN
admet-942	1106	33	https://doi.org/10.1016/j.snr.2021.100031	https://doi.org/10.1016/j.snr.2021.100031	PROPN
admet-942	1106	34	http://creativecommons.org/licenses/by/3.0/	http://creativecommons.org/licenses/by/3.0/	PROPN