id	sid	tid	token	lemma	pos
ijassa-998	1	1	adv	adv	PROPN
ijassa-998	1	2	syst	syst	PROPN
ijassa-998	1	3	sci	sci	PROPN
ijassa-998	1	4	appl	appl	PROPN
ijassa-998	1	5	2020	2020	NUM
ijassa-998	1	6	;	;	PUNCT
ijassa-998	1	7	04:83–104	04:83–104	NUM
ijassa-998	1	8	published	publish	VERB
ijassa-998	1	9	online	online	ADV
ijassa-998	1	10	at	at	ADP
ijassa-998	1	11	https://ijassa.ipu.ru	https://ijassa.ipu.ru	ADV
ijassa-998	1	12	.	.	PUNCT
ijassa-998	2	1	on	on	ADP
ijassa-998	2	2	optimal	optimal	ADJ
ijassa-998	2	3	therapy	therapy	NOUN
ijassa-998	2	4	protocols	protocol	NOUN
ijassa-998	2	5	in	in	ADP
ijassa-998	2	6	the	the	DET
ijassa-998	2	7	mathematical	mathematical	ADJ
ijassa-998	2	8	model	model	NOUN
ijassa-998	2	9	of	of	ADP
ijassa-998	2	10	prostate	prostate	NOUN
ijassa-998	2	11	cancer	cancer	NOUN
ijassa-998	2	12	progression	progression	NOUN
ijassa-998	2	13	marie	marie	PROPN
ijassa-998	2	14	-	-	PUNCT
ijassa-998	2	15	christin	christin	PROPN
ijassa-998	2	16	litzinger1	litzinger1	PROPN
ijassa-998	2	17	,	,	PUNCT
ijassa-998	2	18	y.	y.	PROPN
ijassa-998	2	19	todorov1	todorov1	PROPN
ijassa-998	2	20	,	,	PUNCT
ijassa-998	2	21	miriam	miriam	PROPN
ijassa-998	2	22	föller	föller	PROPN
ijassa-998	2	23	-	-	PUNCT
ijassa-998	2	24	nord1	nord1	PROPN
ijassa-998	2	25	,	,	PUNCT
ijassa-998	2	26	manitjaiswal	manitjaiswal	PROPN
ijassa-998	2	27	k.	k.	PROPN
ijassa-998	2	28	chaudhary2	chaudhary2	PROPN
ijassa-998	2	29	,	,	PUNCT
ijassa-998	2	30	alexander	alexander	PROPN
ijassa-998	2	31	s.	s.	PROPN
ijassa-998	2	32	bratus3,4∗	bratus3,4∗	PROPN
ijassa-998	2	33	1university	1university	NUM
ijassa-998	2	34	of	of	ADP
ijassa-998	2	35	applied	apply	VERB
ijassa-998	2	36	sciences	science	NOUN
ijassa-998	2	37	,	,	PUNCT
ijassa-998	2	38	paul	paul	PROPN
ijassa-998	2	39	-	-	PUNCT
ijassa-998	2	40	wittsack	wittsack	PROPN
ijassa-998	2	41	-	-	PUNCT
ijassa-998	2	42	str	str	NOUN
ijassa-998	2	43	.	.	PUNCT
ijassa-998	3	1	10	10	NUM
ijassa-998	3	2	,	,	PUNCT
ijassa-998	3	3	68163	68163	NUM
ijassa-998	3	4	,	,	PUNCT
ijassa-998	3	5	mannheim	mannheim	PROPN
ijassa-998	3	6	,	,	PUNCT
ijassa-998	3	7	germany	germany	PROPN
ijassa-998	3	8	2nikolsky	2nikolsky	PROPN
ijassa-998	3	9	mathematical	mathematical	ADJ
ijassa-998	3	10	institute	institute	NOUN
ijassa-998	3	11	,	,	PUNCT
ijassa-998	3	12	rudn	rudn	PROPN
ijassa-998	3	13	university	university	NOUN
ijassa-998	3	14	,	,	PUNCT
ijassa-998	3	15	miklukho	miklukho	PROPN
ijassa-998	3	16	-	-	PUNCT
ijassa-998	3	17	maklaya	maklaya	PROPN
ijassa-998	3	18	str.6	str.6	PROPN
ijassa-998	3	19	,	,	PUNCT
ijassa-998	3	20	moscow	moscow	PROPN
ijassa-998	3	21	,	,	PUNCT
ijassa-998	3	22	117198	117198	NUM
ijassa-998	3	23	,	,	PUNCT
ijassa-998	3	24	russia	russia	PROPN
ijassa-998	3	25	3russian	3russian	PROPN
ijassa-998	3	26	university	university	PROPN
ijassa-998	3	27	of	of	ADP
ijassa-998	3	28	transport	transport	NOUN
ijassa-998	3	29	,	,	PUNCT
ijassa-998	3	30	obraztsova	obraztsova	X
ijassa-998	3	31	15	15	NUM
ijassa-998	3	32	,	,	PUNCT
ijassa-998	3	33	moscow	moscow	PROPN
ijassa-998	3	34	,	,	PUNCT
ijassa-998	3	35	127994	127994	NUM
ijassa-998	3	36	,	,	PUNCT
ijassa-998	3	37	russia	russia	PROPN
ijassa-998	3	38	4moscow	4moscow	NUM
ijassa-998	3	39	center	center	NOUN
ijassa-998	3	40	of	of	ADP
ijassa-998	3	41	fundamental	fundamental	ADJ
ijassa-998	3	42	and	and	CCONJ
ijassa-998	3	43	applied	applied	ADJ
ijassa-998	3	44	mathematics	mathematic	NOUN
ijassa-998	3	45	,	,	PUNCT
ijassa-998	3	46	msu	msu	PROPN
ijassa-998	3	47	,	,	PUNCT
ijassa-998	3	48	gsp-1	gsp-1	NOUN
ijassa-998	3	49	,	,	PUNCT
ijassa-998	3	50	leninskie	leninskie	ADJ
ijassa-998	3	51	gory	gory	NOUN
ijassa-998	3	52	,	,	PUNCT
ijassa-998	3	53	moscow	moscow	PROPN
ijassa-998	3	54	,	,	PUNCT
ijassa-998	3	55	119991	119991	NUM
ijassa-998	3	56	,	,	PUNCT
ijassa-998	3	57	russia	russia	PROPN
ijassa-998	3	58	abstract	abstract	NOUN
ijassa-998	3	59	:	:	PUNCT
ijassa-998	3	60	a	a	DET
ijassa-998	3	61	mathematical	mathematical	ADJ
ijassa-998	3	62	model	model	NOUN
ijassa-998	3	63	for	for	ADP
ijassa-998	3	64	the	the	DET
ijassa-998	3	65	treatment	treatment	NOUN
ijassa-998	3	66	of	of	ADP
ijassa-998	3	67	prostate	prostate	NOUN
ijassa-998	3	68	cancer	cancer	NOUN
ijassa-998	3	69	regarding	regard	VERB
ijassa-998	3	70	androgen	androgen	NOUN
ijassa-998	3	71	ablation	ablation	NOUN
ijassa-998	3	72	is	be	AUX
ijassa-998	3	73	considered	consider	VERB
ijassa-998	3	74	.	.	PUNCT
ijassa-998	4	1	the	the	DET
ijassa-998	4	2	effect	effect	NOUN
ijassa-998	4	3	of	of	ADP
ijassa-998	4	4	the	the	DET
ijassa-998	4	5	therapy	therapy	NOUN
ijassa-998	4	6	on	on	ADP
ijassa-998	4	7	healthy	healthy	ADJ
ijassa-998	4	8	cells	cell	NOUN
ijassa-998	4	9	is	be	AUX
ijassa-998	4	10	taken	take	VERB
ijassa-998	4	11	into	into	ADP
ijassa-998	4	12	account	account	NOUN
ijassa-998	4	13	and	and	CCONJ
ijassa-998	4	14	modelled	model	VERB
ijassa-998	4	15	as	as	ADP
ijassa-998	4	16	a	a	DET
ijassa-998	4	17	second	second	ADJ
ijassa-998	4	18	order	order	NOUN
ijassa-998	4	19	state	state	NOUN
ijassa-998	4	20	constraint	constraint	NOUN
ijassa-998	4	21	.	.	PUNCT
ijassa-998	5	1	a	a	DET
ijassa-998	5	2	mathematical	mathematical	ADJ
ijassa-998	5	3	overview	overview	NOUN
ijassa-998	5	4	about	about	ADP
ijassa-998	5	5	possible	possible	ADJ
ijassa-998	5	6	therapy	therapy	NOUN
ijassa-998	5	7	strategies	strategy	NOUN
ijassa-998	5	8	is	be	AUX
ijassa-998	5	9	presented	present	VERB
ijassa-998	5	10	.	.	PUNCT
ijassa-998	6	1	keywords	keyword	NOUN
ijassa-998	6	2	:	:	PUNCT
ijassa-998	6	3	prostate	prostate	NOUN
ijassa-998	6	4	cancer	cancer	NOUN
ijassa-998	6	5	,	,	PUNCT
ijassa-998	6	6	androgen	androgen	NOUN
ijassa-998	6	7	ablation	ablation	NOUN
ijassa-998	6	8	,	,	PUNCT
ijassa-998	6	9	therapy	therapy	NOUN
ijassa-998	6	10	strategies	strategy	NOUN
ijassa-998	6	11	,	,	PUNCT
ijassa-998	6	12	optimal	optimal	ADJ
ijassa-998	6	13	control	control	NOUN
ijassa-998	6	14	,	,	PUNCT
ijassa-998	6	15	state	state	NOUN
ijassa-998	6	16	constraint	constraint	NOUN
ijassa-998	6	17	1	1	NUM
ijassa-998	6	18	.	.	PUNCT
ijassa-998	6	19	introduction	introduction	NOUN
ijassa-998	6	20	regarding	regard	VERB
ijassa-998	6	21	prostate	prostate	NOUN
ijassa-998	6	22	cancer	cancer	NOUN
ijassa-998	6	23	progression	progression	NOUN
ijassa-998	6	24	and	and	CCONJ
ijassa-998	6	25	development	development	NOUN
ijassa-998	6	26	testosterone	testosterone	NOUN
ijassa-998	6	27	and	and	CCONJ
ijassa-998	6	28	its	its	PRON
ijassa-998	6	29	role	role	NOUN
ijassa-998	6	30	in	in	ADP
ijassa-998	6	31	the	the	DET
ijassa-998	6	32	biological	biological	ADJ
ijassa-998	6	33	mechanisms	mechanism	NOUN
ijassa-998	6	34	of	of	ADP
ijassa-998	6	35	epithelial	epithelial	ADJ
ijassa-998	6	36	prostate	prostate	NOUN
ijassa-998	6	37	cells	cell	NOUN
ijassa-998	6	38	are	be	AUX
ijassa-998	6	39	of	of	ADP
ijassa-998	6	40	particular	particular	ADJ
ijassa-998	6	41	interest	interest	NOUN
ijassa-998	6	42	for	for	ADP
ijassa-998	6	43	developing	develop	VERB
ijassa-998	6	44	therapy	therapy	NOUN
ijassa-998	6	45	strategies	strategy	NOUN
ijassa-998	6	46	.	.	PUNCT
ijassa-998	7	1	therefore	therefore	ADV
ijassa-998	7	2	the	the	DET
ijassa-998	7	3	main	main	ADJ
ijassa-998	7	4	steps	step	NOUN
ijassa-998	7	5	of	of	ADP
ijassa-998	7	6	testosterone	testosterone	NOUN
ijassa-998	7	7	procession	procession	NOUN
ijassa-998	7	8	are	be	AUX
ijassa-998	7	9	now	now	ADV
ijassa-998	7	10	outlined	outline	VERB
ijassa-998	7	11	briefly	briefly	ADV
ijassa-998	7	12	.	.	PUNCT
ijassa-998	8	1	after	after	ADP
ijassa-998	8	2	entering	enter	VERB
ijassa-998	8	3	the	the	DET
ijassa-998	8	4	cells	cell	NOUN
ijassa-998	8	5	testosterone	testosterone	NOUN
ijassa-998	8	6	is	be	AUX
ijassa-998	8	7	either	either	CCONJ
ijassa-998	8	8	able	able	ADJ
ijassa-998	8	9	to	to	PART
ijassa-998	8	10	bind	bind	VERB
ijassa-998	8	11	to	to	ADP
ijassa-998	8	12	androgen	androgen	NOUN
ijassa-998	8	13	receptors	receptor	NOUN
ijassa-998	8	14	(	(	PUNCT
ijassa-998	8	15	ar	ar	NOUN
ijassa-998	8	16	)	)	PUNCT
ijassa-998	8	17	straight	straight	ADV
ijassa-998	8	18	away	away	ADV
ijassa-998	8	19	or	or	CCONJ
ijassa-998	8	20	it	it	PRON
ijassa-998	8	21	is	be	AUX
ijassa-998	8	22	first	first	ADV
ijassa-998	8	23	converted	convert	VERB
ijassa-998	8	24	to	to	ADP
ijassa-998	8	25	dihydrotestosterone	dihydrotestosterone	NOUN
ijassa-998	8	26	(	(	PUNCT
ijassa-998	8	27	dht	dht	NOUN
ijassa-998	8	28	)	)	PUNCT
ijassa-998	8	29	.	.	PUNCT
ijassa-998	9	1	in	in	ADP
ijassa-998	9	2	contrast	contrast	NOUN
ijassa-998	9	3	to	to	ADP
ijassa-998	9	4	testosterone	testosterone	NOUN
ijassa-998	9	5	,	,	PUNCT
ijassa-998	9	6	dht	dht	NOUN
ijassa-998	9	7	and	and	CCONJ
ijassa-998	9	8	ar	ar	NOUN
ijassa-998	9	9	form	form	NOUN
ijassa-998	9	10	a	a	DET
ijassa-998	9	11	more	more	ADV
ijassa-998	9	12	stable	stable	ADJ
ijassa-998	9	13	complex	complex	NOUN
ijassa-998	9	14	.	.	PUNCT
ijassa-998	10	1	after	after	ADP
ijassa-998	10	2	being	be	AUX
ijassa-998	10	3	phosphorylated	phosphorylate	VERB
ijassa-998	10	4	and	and	CCONJ
ijassa-998	10	5	dimerized	dimerize	VERB
ijassa-998	10	6	that	that	SCONJ
ijassa-998	10	7	complex	complex	ADJ
ijassa-998	10	8	binds	bind	VERB
ijassa-998	10	9	to	to	ADP
ijassa-998	10	10	the	the	DET
ijassa-998	10	11	dna	dna	NOUN
ijassa-998	10	12	,	,	PUNCT
ijassa-998	10	13	where	where	SCONJ
ijassa-998	10	14	it	it	PRON
ijassa-998	10	15	causes	cause	VERB
ijassa-998	10	16	a	a	DET
ijassa-998	10	17	higher	high	ADJ
ijassa-998	10	18	transcription	transcription	NOUN
ijassa-998	10	19	rate	rate	NOUN
ijassa-998	10	20	of	of	ADP
ijassa-998	10	21	with	with	ADP
ijassa-998	10	22	proliferation	proliferation	NOUN
ijassa-998	10	23	,	,	PUNCT
ijassa-998	10	24	survival	survival	NOUN
ijassa-998	10	25	and	and	CCONJ
ijassa-998	10	26	differentiation	differentiation	NOUN
ijassa-998	10	27	associated	associate	VERB
ijassa-998	10	28	genes	gene	NOUN
ijassa-998	11	1	[	[	X
ijassa-998	11	2	11][10	11][10	X
ijassa-998	11	3	]	]	PUNCT
ijassa-998	11	4	.	.	PUNCT
ijassa-998	12	1	consequently	consequently	ADV
ijassa-998	12	2	,	,	PUNCT
ijassa-998	12	3	there	there	PRON
ijassa-998	12	4	are	be	VERB
ijassa-998	12	5	several	several	ADJ
ijassa-998	12	6	points	point	NOUN
ijassa-998	12	7	in	in	ADP
ijassa-998	12	8	the	the	DET
ijassa-998	12	9	mechanism	mechanism	NOUN
ijassa-998	12	10	where	where	SCONJ
ijassa-998	12	11	the	the	DET
ijassa-998	12	12	therapy	therapy	NOUN
ijassa-998	12	13	can	can	AUX
ijassa-998	12	14	intervene	intervene	VERB
ijassa-998	12	15	,	,	PUNCT
ijassa-998	12	16	for	for	ADP
ijassa-998	12	17	example	example	NOUN
ijassa-998	12	18	through	through	ADP
ijassa-998	12	19	inhibiting	inhibit	VERB
ijassa-998	12	20	the	the	DET
ijassa-998	12	21	testosterone	testosterone	NOUN
ijassa-998	12	22	production	production	NOUN
ijassa-998	12	23	or	or	CCONJ
ijassa-998	12	24	blocking	block	VERB
ijassa-998	12	25	androgen	androgen	NOUN
ijassa-998	12	26	receptors	receptor	NOUN
ijassa-998	12	27	[	[	X
ijassa-998	12	28	2	2	NUM
ijassa-998	12	29	]	]	PUNCT
ijassa-998	12	30	.	.	PUNCT
ijassa-998	13	1	after	after	ADP
ijassa-998	13	2	some	some	DET
ijassa-998	13	3	time	time	NOUN
ijassa-998	13	4	prostate	prostate	NOUN
ijassa-998	13	5	cancer	cancer	NOUN
ijassa-998	13	6	cells	cell	NOUN
ijassa-998	13	7	are	be	AUX
ijassa-998	13	8	able	able	ADJ
ijassa-998	13	9	to	to	PART
ijassa-998	13	10	grow	grow	VERB
ijassa-998	13	11	even	even	ADV
ijassa-998	13	12	in	in	ADP
ijassa-998	13	13	the	the	DET
ijassa-998	13	14	absence	absence	NOUN
ijassa-998	13	15	of	of	ADP
ijassa-998	13	16	androgen	androgen	NOUN
ijassa-998	13	17	.	.	PUNCT
ijassa-998	14	1	due	due	ADP
ijassa-998	14	2	to	to	ADP
ijassa-998	14	3	the	the	DET
ijassa-998	14	4	following	follow	VERB
ijassa-998	14	5	therapy	therapy	NOUN
ijassa-998	14	6	resistance	resistance	NOUN
ijassa-998	14	7	an	an	DET
ijassa-998	14	8	intermittent	intermittent	ADJ
ijassa-998	14	9	androgen	androgen	NOUN
ijassa-998	14	10	therapy	therapy	NOUN
ijassa-998	14	11	can	can	AUX
ijassa-998	14	12	be	be	AUX
ijassa-998	14	13	applied	apply	VERB
ijassa-998	14	14	[	[	PUNCT
ijassa-998	14	15	9	9	NUM
ijassa-998	14	16	,	,	PUNCT
ijassa-998	14	17	19	19	NUM
ijassa-998	14	18	]	]	PUNCT
ijassa-998	14	19	.	.	PUNCT
ijassa-998	15	1	it	it	PRON
ijassa-998	15	2	is	be	AUX
ijassa-998	15	3	important	important	ADJ
ijassa-998	15	4	that	that	SCONJ
ijassa-998	15	5	healthy	healthy	ADJ
ijassa-998	15	6	and	and	CCONJ
ijassa-998	15	7	cancer	cancer	NOUN
ijassa-998	15	8	cells	cell	NOUN
ijassa-998	15	9	both	both	PRON
ijassa-998	15	10	produce	produce	VERB
ijassa-998	15	11	prostate	prostate	NOUN
ijassa-998	15	12	-	-	PUNCT
ijassa-998	15	13	specific	specific	ADJ
ijassa-998	15	14	antigene	antigene	NOUN
ijassa-998	15	15	(	(	PUNCT
ijassa-998	15	16	psa	psa	NOUN
ijassa-998	15	17	)	)	PUNCT
ijassa-998	15	18	.	.	PUNCT
ijassa-998	16	1	in	in	ADP
ijassa-998	16	2	noncancerous	noncancerous	ADJ
ijassa-998	16	3	cells	cell	NOUN
ijassa-998	16	4	only	only	ADV
ijassa-998	16	5	a	a	DET
ijassa-998	16	6	limited	limited	ADJ
ijassa-998	16	7	amount	amount	NOUN
ijassa-998	16	8	of	of	ADP
ijassa-998	16	9	psa	psa	NOUN
ijassa-998	16	10	enters	enter	NOUN
ijassa-998	16	11	into	into	ADP
ijassa-998	16	12	the	the	DET
ijassa-998	16	13	bloodstream	bloodstream	NOUN
ijassa-998	16	14	due	due	ADP
ijassa-998	16	15	to	to	ADP
ijassa-998	16	16	natural	natural	ADJ
ijassa-998	16	17	barriers	barrier	NOUN
ijassa-998	16	18	.	.	PUNCT
ijassa-998	17	1	in	in	ADP
ijassa-998	17	2	the	the	DET
ijassa-998	17	3	presence	presence	NOUN
ijassa-998	17	4	of	of	ADP
ijassa-998	17	5	cancer	cancer	NOUN
ijassa-998	17	6	these	these	DET
ijassa-998	17	7	barriers	barrier	NOUN
ijassa-998	17	8	break	break	VERB
ijassa-998	17	9	down	down	ADP
ijassa-998	17	10	and	and	CCONJ
ijassa-998	17	11	more	more	ADJ
ijassa-998	17	12	psa	psa	VERB
ijassa-998	17	13	leaks	leak	NOUN
ijassa-998	17	14	into	into	ADP
ijassa-998	17	15	the	the	DET
ijassa-998	17	16	blood	blood	NOUN
ijassa-998	17	17	.	.	PUNCT
ijassa-998	18	1	the	the	DET
ijassa-998	18	2	psa	psa	NOUN
ijassa-998	18	3	-	-	PUNCT
ijassa-998	18	4	level	level	NOUN
ijassa-998	18	5	in	in	ADP
ijassa-998	18	6	the	the	DET
ijassa-998	18	7	blood	blood	NOUN
ijassa-998	18	8	serum	serum	NOUN
ijassa-998	18	9	therefore	therefore	ADV
ijassa-998	18	10	acts	act	VERB
ijassa-998	18	11	as	as	ADP
ijassa-998	18	12	an	an	DET
ijassa-998	18	13	indicator	indicator	NOUN
ijassa-998	18	14	for	for	ADP
ijassa-998	18	15	the	the	DET
ijassa-998	18	16	stadium	stadium	NOUN
ijassa-998	18	17	and	and	CCONJ
ijassa-998	18	18	the	the	DET
ijassa-998	18	19	presence	presence	NOUN
ijassa-998	18	20	of	of	ADP
ijassa-998	18	21	prostate	prostate	NOUN
ijassa-998	18	22	cancer	cancer	NOUN
ijassa-998	18	23	[	[	X
ijassa-998	18	24	11	11	NUM
ijassa-998	18	25	]	]	PUNCT
ijassa-998	18	26	.	.	PUNCT
ijassa-998	19	1	due	due	ADP
ijassa-998	19	2	to	to	ADP
ijassa-998	19	3	the	the	DET
ijassa-998	19	4	complex	complex	ADJ
ijassa-998	19	5	mechanisms	mechanism	NOUN
ijassa-998	19	6	of	of	ADP
ijassa-998	19	7	cancer	cancer	NOUN
ijassa-998	19	8	the	the	DET
ijassa-998	19	9	cooperation	cooperation	NOUN
ijassa-998	19	10	of	of	ADP
ijassa-998	19	11	different	different	ADJ
ijassa-998	19	12	scientific	scientific	ADJ
ijassa-998	19	13	areas	area	NOUN
ijassa-998	19	14	is	be	AUX
ijassa-998	19	15	necessary	necessary	ADJ
ijassa-998	19	16	and	and	CCONJ
ijassa-998	19	17	mentioned	mention	VERB
ijassa-998	19	18	in	in	ADP
ijassa-998	19	19	[	[	X
ijassa-998	19	20	3	3	NUM
ijassa-998	19	21	]	]	PUNCT
ijassa-998	19	22	and	and	CCONJ
ijassa-998	19	23	[	[	X
ijassa-998	19	24	6	6	NUM
ijassa-998	19	25	]	]	PUNCT
ijassa-998	19	26	.	.	PUNCT
ijassa-998	20	1	since	since	SCONJ
ijassa-998	20	2	the	the	DET
ijassa-998	20	3	last	last	ADJ
ijassa-998	20	4	fifty	fifty	NUM
ijassa-998	20	5	years	year	NOUN
ijassa-998	20	6	the	the	DET
ijassa-998	20	7	application	application	NOUN
ijassa-998	20	8	of	of	ADP
ijassa-998	20	9	∗corresponding	∗corresponde	VERB
ijassa-998	20	10	author	author	NOUN
ijassa-998	20	11	:	:	PUNCT
ijassa-998	20	12	alexander.bratus@yandex.ru	alexander.bratus@yandex.ru	VERB
ijassa-998	20	13	84	84	NUM
ijassa-998	20	14	m.-c	m.-c	NOUN
ijassa-998	20	15	.	.	PUNCT
ijassa-998	21	1	litzinger	litzinger	NOUN
ijassa-998	21	2	,	,	PUNCT
ijassa-998	21	3	y.	y.	PROPN
ijassa-998	21	4	todorov	todorov	PROPN
ijassa-998	21	5	,	,	PUNCT
ijassa-998	21	6	m.	m.	NOUN
ijassa-998	21	7	föller	föller	PROPN
ijassa-998	21	8	-	-	PUNCT
ijassa-998	21	9	nord	nord	PROPN
ijassa-998	21	10	,	,	PUNCT
ijassa-998	21	11	m.k	m.k	PROPN
ijassa-998	21	12	.	.	PUNCT
ijassa-998	21	13	chaudhary	chaudhary	PROPN
ijassa-998	21	14	,	,	PUNCT
ijassa-998	21	15	a.s	a.s	PROPN
ijassa-998	21	16	.	.	PROPN
ijassa-998	21	17	bratus	bratus	PROPN
ijassa-998	21	18	mathematical	mathematical	ADJ
ijassa-998	21	19	approaches	approach	NOUN
ijassa-998	21	20	in	in	ADP
ijassa-998	21	21	order	order	NOUN
ijassa-998	21	22	to	to	PART
ijassa-998	21	23	analyze	analyze	VERB
ijassa-998	21	24	the	the	DET
ijassa-998	21	25	dynamics	dynamic	NOUN
ijassa-998	21	26	of	of	ADP
ijassa-998	21	27	cancer	cancer	NOUN
ijassa-998	21	28	is	be	AUX
ijassa-998	21	29	therefore	therefore	ADV
ijassa-998	21	30	common	common	ADJ
ijassa-998	21	31	and	and	CCONJ
ijassa-998	21	32	discussed	discuss	VERB
ijassa-998	21	33	in	in	ADP
ijassa-998	21	34	[	[	X
ijassa-998	21	35	3	3	NUM
ijassa-998	21	36	]	]	PUNCT
ijassa-998	21	37	.	.	PUNCT
ijassa-998	22	1	furthermore	furthermore	ADV
ijassa-998	22	2	mathematical	mathematical	ADJ
ijassa-998	22	3	models	model	NOUN
ijassa-998	22	4	and	and	CCONJ
ijassa-998	22	5	methods	method	NOUN
ijassa-998	22	6	for	for	ADP
ijassa-998	22	7	the	the	DET
ijassa-998	22	8	analysis	analysis	NOUN
ijassa-998	22	9	of	of	ADP
ijassa-998	22	10	the	the	DET
ijassa-998	22	11	dynamics	dynamic	NOUN
ijassa-998	22	12	of	of	ADP
ijassa-998	22	13	tumor	tumor	NOUN
ijassa-998	22	14	-	-	PUNCT
ijassa-998	22	15	immune	immune	ADJ
ijassa-998	22	16	interaction	interaction	NOUN
ijassa-998	22	17	are	be	AUX
ijassa-998	22	18	considered	consider	VERB
ijassa-998	22	19	to	to	PART
ijassa-998	22	20	evolve	evolve	VERB
ijassa-998	22	21	research	research	NOUN
ijassa-998	22	22	perspectives	perspective	NOUN
ijassa-998	22	23	[	[	X
ijassa-998	22	24	4	4	NUM
ijassa-998	22	25	]	]	PUNCT
ijassa-998	22	26	.	.	PUNCT
ijassa-998	23	1	however	however	ADV
ijassa-998	23	2	,	,	PUNCT
ijassa-998	23	3	not	not	PART
ijassa-998	23	4	only	only	ADV
ijassa-998	23	5	the	the	DET
ijassa-998	23	6	competition	competition	NOUN
ijassa-998	23	7	between	between	ADP
ijassa-998	23	8	cancer	cancer	NOUN
ijassa-998	23	9	and	and	CCONJ
ijassa-998	23	10	healthy	healthy	ADJ
ijassa-998	23	11	cells	cell	NOUN
ijassa-998	23	12	,	,	PUNCT
ijassa-998	23	13	but	but	CCONJ
ijassa-998	23	14	also	also	ADV
ijassa-998	23	15	the	the	DET
ijassa-998	23	16	toxicity	toxicity	NOUN
ijassa-998	23	17	of	of	ADP
ijassa-998	23	18	the	the	DET
ijassa-998	23	19	therapy	therapy	NOUN
ijassa-998	23	20	,	,	PUNCT
ijassa-998	23	21	which	which	PRON
ijassa-998	23	22	damages	damage	VERB
ijassa-998	23	23	healthy	healthy	ADJ
ijassa-998	23	24	cells	cell	NOUN
ijassa-998	23	25	,	,	PUNCT
ijassa-998	23	26	are	be	AUX
ijassa-998	23	27	negative	negative	ADJ
ijassa-998	23	28	side	side	ADJ
ijassa-998	23	29	effects	effect	NOUN
ijassa-998	23	30	.	.	PUNCT
ijassa-998	24	1	these	these	PRON
ijassa-998	24	2	are	be	AUX
ijassa-998	24	3	essential	essential	ADJ
ijassa-998	24	4	for	for	ADP
ijassa-998	24	5	developing	develop	VERB
ijassa-998	24	6	effective	effective	ADJ
ijassa-998	24	7	medicine	medicine	NOUN
ijassa-998	24	8	and	and	CCONJ
ijassa-998	24	9	therapy	therapy	NOUN
ijassa-998	24	10	strategies	strategy	NOUN
ijassa-998	24	11	.	.	PUNCT
ijassa-998	25	1	consequently	consequently	ADV
ijassa-998	25	2	,	,	PUNCT
ijassa-998	25	3	the	the	DET
ijassa-998	25	4	mathematical	mathematical	ADJ
ijassa-998	25	5	theory	theory	NOUN
ijassa-998	25	6	of	of	ADP
ijassa-998	25	7	optimal	optimal	ADJ
ijassa-998	25	8	control	control	NOUN
ijassa-998	25	9	processes	process	NOUN
ijassa-998	25	10	is	be	AUX
ijassa-998	25	11	needed	need	VERB
ijassa-998	25	12	to	to	PART
ijassa-998	25	13	develop	develop	VERB
ijassa-998	25	14	successful	successful	ADJ
ijassa-998	25	15	therapy	therapy	NOUN
ijassa-998	25	16	protocols	protocol	NOUN
ijassa-998	26	1	[	[	X
ijassa-998	26	2	17][22	17][22	X
ijassa-998	26	3	]	]	X
ijassa-998	26	4	.	.	PUNCT
ijassa-998	27	1	due	due	ADP
ijassa-998	27	2	to	to	ADP
ijassa-998	27	3	the	the	DET
ijassa-998	27	4	adverse	adverse	ADJ
ijassa-998	27	5	effects	effect	NOUN
ijassa-998	27	6	caused	cause	VERB
ijassa-998	27	7	by	by	ADP
ijassa-998	27	8	the	the	DET
ijassa-998	27	9	ablation	ablation	NOUN
ijassa-998	27	10	of	of	ADP
ijassa-998	27	11	androgen	androgen	NOUN
ijassa-998	27	12	,	,	PUNCT
ijassa-998	27	13	for	for	ADP
ijassa-998	27	14	example	example	NOUN
ijassa-998	27	15	the	the	DET
ijassa-998	27	16	decrease	decrease	NOUN
ijassa-998	27	17	of	of	ADP
ijassa-998	27	18	quality	quality	NOUN
ijassa-998	27	19	of	of	ADP
ijassa-998	27	20	life	life	NOUN
ijassa-998	27	21	[	[	X
ijassa-998	27	22	5	5	NUM
ijassa-998	27	23	]	]	PUNCT
ijassa-998	27	24	,	,	PUNCT
ijassa-998	27	25	it	it	PRON
ijassa-998	27	26	is	be	AUX
ijassa-998	27	27	convenient	convenient	ADJ
ijassa-998	27	28	to	to	PART
ijassa-998	27	29	introduce	introduce	VERB
ijassa-998	27	30	a	a	DET
ijassa-998	27	31	limitation	limitation	NOUN
ijassa-998	27	32	of	of	ADP
ijassa-998	27	33	the	the	DET
ijassa-998	27	34	healthy	healthy	ADJ
ijassa-998	27	35	epithelial	epithelial	ADJ
ijassa-998	27	36	prostate	prostate	NOUN
ijassa-998	27	37	cells	cell	NOUN
ijassa-998	27	38	during	during	ADP
ijassa-998	27	39	androgen	androgen	NOUN
ijassa-998	27	40	ablation	ablation	NOUN
ijassa-998	27	41	therapy	therapy	NOUN
ijassa-998	27	42	.	.	PUNCT
ijassa-998	28	1	in	in	ADP
ijassa-998	28	2	the	the	DET
ijassa-998	28	3	present	present	ADJ
ijassa-998	28	4	work	work	NOUN
ijassa-998	28	5	three	three	NUM
ijassa-998	28	6	approaches	approach	NOUN
ijassa-998	28	7	–	–	PUNCT
ijassa-998	28	8	an	an	DET
ijassa-998	28	9	alternative	alternative	NOUN
ijassa-998	28	10	,	,	PUNCT
ijassa-998	28	11	suboptimal	suboptimal	ADJ
ijassa-998	28	12	and	and	CCONJ
ijassa-998	28	13	optimal	optimal	ADJ
ijassa-998	28	14	one	one	NOUN
ijassa-998	28	15	–	–	PUNCT
ijassa-998	28	16	in	in	ADP
ijassa-998	28	17	the	the	DET
ijassa-998	28	18	mathematical	mathematical	ADJ
ijassa-998	28	19	model	model	NOUN
ijassa-998	28	20	for	for	ADP
ijassa-998	28	21	prostate	prostate	NOUN
ijassa-998	28	22	cancer	cancer	NOUN
ijassa-998	28	23	progression	progression	NOUN
ijassa-998	28	24	in	in	ADP
ijassa-998	28	25	response	response	NOUN
ijassa-998	28	26	to	to	ADP
ijassa-998	28	27	androgen	androgen	NOUN
ijassa-998	28	28	ablation	ablation	NOUN
ijassa-998	28	29	therapy	therapy	NOUN
ijassa-998	28	30	are	be	AUX
ijassa-998	28	31	introduced	introduce	VERB
ijassa-998	28	32	.	.	PUNCT
ijassa-998	29	1	in	in	ADP
ijassa-998	29	2	all	all	DET
ijassa-998	29	3	three	three	NUM
ijassa-998	29	4	approaches	approach	NOUN
ijassa-998	29	5	the	the	DET
ijassa-998	29	6	side	side	NOUN
ijassa-998	29	7	effects	effect	NOUN
ijassa-998	29	8	of	of	ADP
ijassa-998	29	9	the	the	DET
ijassa-998	29	10	androgen	androgen	NOUN
ijassa-998	29	11	ablation	ablation	NOUN
ijassa-998	29	12	therapy	therapy	NOUN
ijassa-998	29	13	are	be	AUX
ijassa-998	29	14	considered	consider	VERB
ijassa-998	29	15	as	as	ADP
ijassa-998	29	16	a	a	DET
ijassa-998	29	17	second	second	ADJ
ijassa-998	29	18	order	order	NOUN
ijassa-998	29	19	pure	pure	ADJ
ijassa-998	29	20	state	state	NOUN
ijassa-998	29	21	constraint	constraint	NOUN
ijassa-998	29	22	on	on	ADP
ijassa-998	29	23	the	the	DET
ijassa-998	29	24	amount	amount	NOUN
ijassa-998	29	25	of	of	ADP
ijassa-998	29	26	the	the	DET
ijassa-998	29	27	healthy	healthy	ADJ
ijassa-998	29	28	epithelial	epithelial	ADJ
ijassa-998	29	29	prostate	prostate	NOUN
ijassa-998	29	30	cells	cell	NOUN
ijassa-998	29	31	.	.	PUNCT
ijassa-998	30	1	the	the	DET
ijassa-998	30	2	goal	goal	NOUN
ijassa-998	30	3	is	be	AUX
ijassa-998	30	4	to	to	PART
ijassa-998	30	5	minimize	minimize	VERB
ijassa-998	30	6	the	the	DET
ijassa-998	30	7	amount	amount	NOUN
ijassa-998	30	8	of	of	ADP
ijassa-998	30	9	cancer	cancer	NOUN
ijassa-998	30	10	cells	cell	NOUN
ijassa-998	30	11	while	while	SCONJ
ijassa-998	30	12	keeping	keep	VERB
ijassa-998	30	13	the	the	DET
ijassa-998	30	14	amount	amount	NOUN
ijassa-998	30	15	of	of	ADP
ijassa-998	30	16	healthy	healthy	ADJ
ijassa-998	30	17	cells	cell	NOUN
ijassa-998	30	18	above	above	ADP
ijassa-998	30	19	a	a	DET
ijassa-998	30	20	given	give	VERB
ijassa-998	30	21	critical	critical	ADJ
ijassa-998	30	22	limit	limit	NOUN
ijassa-998	30	23	.	.	PUNCT
ijassa-998	31	1	the	the	DET
ijassa-998	31	2	resistance	resistance	NOUN
ijassa-998	31	3	of	of	ADP
ijassa-998	31	4	prostate	prostate	NOUN
ijassa-998	31	5	cancer	cancer	NOUN
ijassa-998	31	6	cells	cell	NOUN
ijassa-998	31	7	during	during	ADP
ijassa-998	31	8	the	the	DET
ijassa-998	31	9	androgen	androgen	NOUN
ijassa-998	31	10	ablation	ablation	NOUN
ijassa-998	31	11	therapy	therapy	NOUN
ijassa-998	31	12	is	be	AUX
ijassa-998	31	13	also	also	ADV
ijassa-998	31	14	taken	take	VERB
ijassa-998	31	15	into	into	ADP
ijassa-998	31	16	account	account	NOUN
ijassa-998	31	17	.	.	PUNCT
ijassa-998	32	1	in	in	ADP
ijassa-998	32	2	the	the	DET
ijassa-998	32	3	following	follow	VERB
ijassa-998	32	4	a	a	DET
ijassa-998	32	5	brief	brief	ADJ
ijassa-998	32	6	description	description	NOUN
ijassa-998	32	7	of	of	ADP
ijassa-998	32	8	each	each	DET
ijassa-998	32	9	therapy	therapy	NOUN
ijassa-998	32	10	strategy	strategy	NOUN
ijassa-998	32	11	is	be	AUX
ijassa-998	32	12	given	give	VERB
ijassa-998	32	13	.	.	PUNCT
ijassa-998	33	1	the	the	DET
ijassa-998	33	2	alternative	alternative	ADJ
ijassa-998	33	3	therapy	therapy	NOUN
ijassa-998	33	4	strategy	strategy	NOUN
ijassa-998	33	5	is	be	AUX
ijassa-998	33	6	based	base	VERB
ijassa-998	33	7	on	on	ADP
ijassa-998	33	8	the	the	DET
ijassa-998	33	9	dynamical	dynamical	ADJ
ijassa-998	33	10	analysis	analysis	NOUN
ijassa-998	33	11	of	of	ADP
ijassa-998	33	12	the	the	DET
ijassa-998	33	13	system	system	NOUN
ijassa-998	33	14	and	and	CCONJ
ijassa-998	33	15	its	its	PRON
ijassa-998	33	16	critical	critical	ADJ
ijassa-998	33	17	points	point	NOUN
ijassa-998	33	18	.	.	PUNCT
ijassa-998	34	1	this	this	DET
ijassa-998	34	2	approach	approach	NOUN
ijassa-998	34	3	circumvents	circumvent	VERB
ijassa-998	34	4	the	the	DET
ijassa-998	34	5	classical	classical	ADJ
ijassa-998	34	6	optimal	optimal	ADJ
ijassa-998	34	7	control	control	NOUN
ijassa-998	34	8	theory	theory	NOUN
ijassa-998	34	9	.	.	PUNCT
ijassa-998	35	1	in	in	ADP
ijassa-998	35	2	combination	combination	NOUN
ijassa-998	35	3	with	with	ADP
ijassa-998	35	4	a	a	DET
ijassa-998	35	5	numerical	numerical	ADJ
ijassa-998	35	6	improvement	improvement	NOUN
ijassa-998	35	7	algorithm	algorithm	NOUN
ijassa-998	35	8	it	it	PRON
ijassa-998	35	9	provides	provide	VERB
ijassa-998	35	10	feasible	feasible	ADJ
ijassa-998	35	11	results	result	NOUN
ijassa-998	35	12	which	which	PRON
ijassa-998	35	13	are	be	AUX
ijassa-998	35	14	similar	similar	ADJ
ijassa-998	35	15	to	to	ADP
ijassa-998	35	16	the	the	DET
ijassa-998	35	17	optimal	optimal	ADJ
ijassa-998	35	18	one	one	NOUN
ijassa-998	35	19	.	.	PUNCT
ijassa-998	36	1	pontraygin	pontraygin	PROPN
ijassa-998	36	2	’s	’s	PART
ijassa-998	36	3	maximum	maximum	ADJ
ijassa-998	36	4	principle	principle	NOUN
ijassa-998	36	5	without	without	SCONJ
ijassa-998	36	6	state	state	NOUN
ijassa-998	36	7	constraints	constraint	NOUN
ijassa-998	36	8	is	be	AUX
ijassa-998	36	9	used	use	VERB
ijassa-998	36	10	to	to	PART
ijassa-998	36	11	develop	develop	VERB
ijassa-998	36	12	a	a	DET
ijassa-998	36	13	therapy	therapy	NOUN
ijassa-998	36	14	protocol	protocol	NOUN
ijassa-998	36	15	at	at	ADP
ijassa-998	36	16	which	which	PRON
ijassa-998	36	17	the	the	DET
ijassa-998	36	18	conditions	condition	NOUN
ijassa-998	36	19	of	of	ADP
ijassa-998	36	20	the	the	DET
ijassa-998	36	21	states	state	NOUN
ijassa-998	36	22	on	on	ADP
ijassa-998	36	23	the	the	DET
ijassa-998	36	24	constraint	constraint	NOUN
ijassa-998	36	25	boundary	boundary	NOUN
ijassa-998	36	26	are	be	AUX
ijassa-998	36	27	analyzed	analyze	VERB
ijassa-998	36	28	.	.	PUNCT
ijassa-998	37	1	the	the	DET
ijassa-998	37	2	considered	consider	VERB
ijassa-998	37	3	approach	approach	NOUN
ijassa-998	37	4	always	always	ADV
ijassa-998	37	5	guarantees	guarantee	VERB
ijassa-998	37	6	a	a	DET
ijassa-998	37	7	feasible	feasible	ADJ
ijassa-998	37	8	therapy	therapy	NOUN
ijassa-998	37	9	process	process	NOUN
ijassa-998	37	10	if	if	SCONJ
ijassa-998	37	11	there	there	PRON
ijassa-998	37	12	exists	exist	VERB
ijassa-998	37	13	such	such	ADJ
ijassa-998	37	14	possible	possible	ADJ
ijassa-998	37	15	one	one	NUM
ijassa-998	37	16	.	.	PUNCT
ijassa-998	38	1	the	the	DET
ijassa-998	38	2	results	result	NOUN
ijassa-998	38	3	are	be	AUX
ijassa-998	38	4	used	use	VERB
ijassa-998	38	5	to	to	PART
ijassa-998	38	6	obtain	obtain	VERB
ijassa-998	38	7	the	the	DET
ijassa-998	38	8	so	so	ADV
ijassa-998	38	9	called	call	VERB
ijassa-998	38	10	suboptimal	suboptimal	ADJ
ijassa-998	38	11	therapy	therapy	NOUN
ijassa-998	38	12	strategy	strategy	NOUN
ijassa-998	38	13	.	.	PUNCT
ijassa-998	39	1	an	an	DET
ijassa-998	39	2	analytical	analytical	ADJ
ijassa-998	39	3	determination	determination	NOUN
ijassa-998	39	4	of	of	ADP
ijassa-998	39	5	an	an	DET
ijassa-998	39	6	optimal	optimal	ADJ
ijassa-998	39	7	therapy	therapy	NOUN
ijassa-998	39	8	strategy	strategy	NOUN
ijassa-998	39	9	in	in	ADP
ijassa-998	39	10	the	the	DET
ijassa-998	39	11	presence	presence	NOUN
ijassa-998	39	12	of	of	ADP
ijassa-998	39	13	state	state	NOUN
ijassa-998	39	14	constraints	constraint	NOUN
ijassa-998	39	15	of	of	ADP
ijassa-998	39	16	order	order	NOUN
ijassa-998	39	17	two	two	NUM
ijassa-998	39	18	is	be	AUX
ijassa-998	39	19	considered	consider	VERB
ijassa-998	39	20	by	by	ADP
ijassa-998	39	21	means	mean	NOUN
ijassa-998	39	22	of	of	ADP
ijassa-998	39	23	analytical	analytical	ADJ
ijassa-998	39	24	and	and	CCONJ
ijassa-998	39	25	numerical	numerical	ADJ
ijassa-998	39	26	techniques	technique	NOUN
ijassa-998	39	27	.	.	PUNCT
ijassa-998	40	1	therefore	therefore	ADV
ijassa-998	40	2	the	the	DET
ijassa-998	40	3	software	software	NOUN
ijassa-998	40	4	tool	tool	NOUN
ijassa-998	40	5	bocop	bocop	NOUN
ijassa-998	40	6	is	be	AUX
ijassa-998	40	7	used	use	VERB
ijassa-998	40	8	.	.	PUNCT
ijassa-998	41	1	the	the	DET
ijassa-998	41	2	results	result	NOUN
ijassa-998	41	3	of	of	ADP
ijassa-998	41	4	the	the	DET
ijassa-998	41	5	presented	present	VERB
ijassa-998	41	6	approaches	approach	NOUN
ijassa-998	41	7	are	be	AUX
ijassa-998	41	8	compared	compare	VERB
ijassa-998	41	9	and	and	CCONJ
ijassa-998	41	10	discussed	discuss	VERB
ijassa-998	41	11	.	.	PUNCT
ijassa-998	42	1	2	2	X
ijassa-998	42	2	.	.	X
ijassa-998	42	3	mathematical	mathematical	ADJ
ijassa-998	42	4	model	model	NOUN
ijassa-998	42	5	of	of	ADP
ijassa-998	42	6	prostate	prostate	NOUN
ijassa-998	42	7	cancer	cancer	NOUN
ijassa-998	42	8	in	in	ADP
ijassa-998	42	9	this	this	DET
ijassa-998	42	10	article	article	NOUN
ijassa-998	42	11	a	a	DET
ijassa-998	42	12	mathematical	mathematical	ADJ
ijassa-998	42	13	model	model	NOUN
ijassa-998	42	14	of	of	ADP
ijassa-998	42	15	prostate	prostate	NOUN
ijassa-998	42	16	cancer	cancer	NOUN
ijassa-998	42	17	based	base	VERB
ijassa-998	42	18	on	on	ADP
ijassa-998	42	19	[	[	X
ijassa-998	42	20	11	11	NUM
ijassa-998	42	21	]	]	PUNCT
ijassa-998	42	22	is	be	AUX
ijassa-998	42	23	considered	consider	VERB
ijassa-998	42	24	.	.	PUNCT
ijassa-998	43	1	copyright	copyright	NOUN
ijassa-998	43	2	c	c	ADP
ijassa-998	43	3	©	©	PROPN
ijassa-998	43	4	2020	2020	NUM
ijassa-998	43	5	assa	assa	NOUN
ijassa-998	43	6	.	.	PUNCT
ijassa-998	44	1	adv	adv	PROPN
ijassa-998	44	2	syst	syst	PROPN
ijassa-998	44	3	sci	sci	PROPN
ijassa-998	44	4	appl	appl	PROPN
ijassa-998	44	5	(	(	PUNCT
ijassa-998	44	6	2020	2020	NUM
ijassa-998	44	7	)	)	PUNCT
ijassa-998	44	8	on	on	ADP
ijassa-998	44	9	optimal	optimal	ADJ
ijassa-998	44	10	therapy	therapy	NOUN
ijassa-998	44	11	protocols	protocol	NOUN
ijassa-998	44	12	in	in	ADP
ijassa-998	44	13	the	the	DET
ijassa-998	44	14	math	math	NOUN
ijassa-998	44	15	.	.	PUNCT
ijassa-998	45	1	model	model	NOUN
ijassa-998	45	2	of	of	ADP
ijassa-998	45	3	prostate	prostate	NOUN
ijassa-998	45	4	cancer	cancer	NOUN
ijassa-998	45	5	progression	progression	NOUN
ijassa-998	45	6	85	85	NUM
ijassa-998	45	7	de(t	de(t	NUM
ijassa-998	45	8	)	)	PUNCT
ijassa-998	45	9	dt	dt	NOUN
ijassa-998	46	1	=	=	SYM
ijassa-998	46	2	µee(t	µee(t	PROPN
ijassa-998	46	3	)	)	PUNCT
ijassa-998	46	4	(	(	PUNCT
ijassa-998	46	5	1−	1−	NUM
ijassa-998	46	6	e(t	e(t	NOUN
ijassa-998	46	7	)	)	PUNCT
ijassa-998	46	8	ηe	ηe	ADP
ijassa-998	46	9	)	)	PUNCT
ijassa-998	46	10	−	−	PROPN
ijassa-998	46	11	εe(t)(m(t	εe(t)(m(t	NOUN
ijassa-998	46	12	)	)	PUNCT
ijassa-998	47	1	+	+	NOUN
ijassa-998	47	2	n(t	n(t	X
ijassa-998	47	3	)	)	PUNCT
ijassa-998	47	4	)	)	PUNCT
ijassa-998	47	5	ηe	ηe	ADP
ijassa-998	47	6	−	−	PROPN
ijassa-998	47	7	δee(t	δee(t	NOUN
ijassa-998	47	8	)	)	PUNCT
ijassa-998	47	9	dn(t	dn(t	PUNCT
ijassa-998	47	10	)	)	PUNCT
ijassa-998	47	11	dt	dt	NOUN
ijassa-998	48	1	=	=	PUNCT
ijassa-998	48	2	(	(	PUNCT
ijassa-998	48	3	1−	1−	NUM
ijassa-998	48	4	αm)µnn(t	αm)µnn(t	NUM
ijassa-998	48	5	)	)	PUNCT
ijassa-998	48	6	(	(	PUNCT
ijassa-998	48	7	1−	1−	NUM
ijassa-998	48	8	n(t	n(t	PROPN
ijassa-998	48	9	)	)	PUNCT
ijassa-998	49	1	+	+	SYM
ijassa-998	49	2	m(t	m(t	X
ijassa-998	49	3	)	)	PUNCT
ijassa-998	49	4	η	η	PROPN
ijassa-998	49	5	)	)	PUNCT
ijassa-998	49	6	−	−	PROPN
ijassa-998	49	7	δnn(t	δnn(t	PROPN
ijassa-998	49	8	)	)	PUNCT
ijassa-998	49	9	dm(t	dm(t	PUNCT
ijassa-998	49	10	)	)	PUNCT
ijassa-998	50	1	dt	dt	PUNCT
ijassa-998	51	1	=	=	PUNCT
ijassa-998	51	2	(	(	PUNCT
ijassa-998	51	3	µmm(t	µmm(t	SYM
ijassa-998	51	4	)	)	PUNCT
ijassa-998	52	1	+	+	NUM
ijassa-998	52	2	αmµmn(t	αmµmn(t	NUM
ijassa-998	52	3	)	)	PUNCT
ijassa-998	52	4	)	)	PUNCT
ijassa-998	53	1	(	(	PUNCT
ijassa-998	53	2	1−	1−	NUM
ijassa-998	53	3	n(t	n(t	PROPN
ijassa-998	53	4	)	)	PUNCT
ijassa-998	54	1	+	+	SYM
ijassa-998	54	2	m(t	m(t	X
ijassa-998	54	3	)	)	PUNCT
ijassa-998	54	4	η	η	PROPN
ijassa-998	54	5	)	)	PUNCT
ijassa-998	55	1	−	−	ADP
ijassa-998	55	2	δmm(t	δmm(t	PROPN
ijassa-998	55	3	)	)	PUNCT
ijassa-998	55	4	dr(t	dr(t	X
ijassa-998	55	5	)	)	PUNCT
ijassa-998	55	6	dt	dt	NOUN
ijassa-998	56	1	=	=	SYM
ijassa-998	56	2	αr	αr	PROPN
ijassa-998	56	3	−	−	PROPN
ijassa-998	56	4	λrr(t)−	λrr(t)−	PROPN
ijassa-998	56	5	kdf	kdf	PROPN
ijassa-998	56	6	r(t)d(t	r(t)d(t	NOUN
ijassa-998	56	7	)	)	PUNCT
ijassa-998	56	8	+	+	CCONJ
ijassa-998	56	9	kdr	kdr	PROPN
ijassa-998	56	10	a(t)−	a(t)−	PROPN
ijassa-998	56	11	ktf	ktf	PROPN
ijassa-998	56	12	r(t)t	r(t)t	PROPN
ijassa-998	56	13	(	(	PUNCT
ijassa-998	56	14	t	t	PROPN
ijassa-998	56	15	)	)	PUNCT
ijassa-998	57	1	+	+	CCONJ
ijassa-998	57	2	ktr	ktr	PROPN
ijassa-998	57	3	a(t	a(t	NOUN
ijassa-998	57	4	)	)	PUNCT
ijassa-998	57	5	dd(t	dd(t	NOUN
ijassa-998	57	6	)	)	PUNCT
ijassa-998	57	7	dt	dt	NOUN
ijassa-998	58	1	=	=	PUNCT
ijassa-998	58	2	βt	βt	PROPN
ijassa-998	58	3	t	t	PROPN
ijassa-998	58	4	(	(	PUNCT
ijassa-998	58	5	t	t	PROPN
ijassa-998	58	6	)	)	PUNCT
ijassa-998	58	7	kt	kt	PROPN
ijassa-998	59	1	+	+	PROPN
ijassa-998	59	2	t	t	PROPN
ijassa-998	59	3	(	(	PUNCT
ijassa-998	59	4	t	t	PROPN
ijassa-998	59	5	)	)	PUNCT
ijassa-998	59	6	−	−	PROPN
ijassa-998	60	1	λdd(t)−	λdd(t)−	PROPN
ijassa-998	60	2	kdf	kdf	PROPN
ijassa-998	60	3	r(t)d(t	r(t)d(t	NUM
ijassa-998	60	4	)	)	PUNCT
ijassa-998	60	5	+	+	CCONJ
ijassa-998	60	6	kdr	kdr	PROPN
ijassa-998	60	7	a(t	a(t	PROPN
ijassa-998	60	8	)	)	PUNCT
ijassa-998	60	9	dt	dt	X
ijassa-998	60	10	(	(	PUNCT
ijassa-998	60	11	t	t	NOUN
ijassa-998	60	12	)	)	PUNCT
ijassa-998	60	13	dt	dt	NOUN
ijassa-998	61	1	=	=	PUNCT
ijassa-998	61	2	f(ts)−	f(ts)−	X
ijassa-998	62	1	λtt	λtt	PROPN
ijassa-998	62	2	(	(	PUNCT
ijassa-998	62	3	t)−	t)−	PROPN
ijassa-998	62	4	βt	βt	X
ijassa-998	62	5	(	(	PUNCT
ijassa-998	62	6	t	t	PROPN
ijassa-998	62	7	)	)	PUNCT
ijassa-998	62	8	t	t	PROPN
ijassa-998	62	9	(	(	PUNCT
ijassa-998	62	10	t	t	PROPN
ijassa-998	62	11	)	)	PUNCT
ijassa-998	62	12	kt	kt	PROPN
ijassa-998	62	13	+	+	PROPN
ijassa-998	62	14	t	t	PROPN
ijassa-998	62	15	(	(	PUNCT
ijassa-998	62	16	t	t	PROPN
ijassa-998	62	17	)	)	PUNCT
ijassa-998	62	18	−	−	PROPN
ijassa-998	63	1	ktf	ktf	PROPN
ijassa-998	63	2	r(t)t	r(t)t	PROPN
ijassa-998	63	3	(	(	PUNCT
ijassa-998	63	4	t	t	PROPN
ijassa-998	63	5	)	)	PUNCT
ijassa-998	64	1	+	+	CCONJ
ijassa-998	64	2	ktr	ktr	PROPN
ijassa-998	64	3	at(t	at(t	NOUN
ijassa-998	64	4	)	)	PUNCT
ijassa-998	64	5	da(t	da(t	NOUN
ijassa-998	64	6	)	)	PUNCT
ijassa-998	64	7	dt	dt	NOUN
ijassa-998	65	1	=	=	SYM
ijassa-998	65	2	−λaa(t	−λaa(t	PROPN
ijassa-998	65	3	)	)	PUNCT
ijassa-998	66	1	+	+	CCONJ
ijassa-998	66	2	kdf	kdf	PROPN
ijassa-998	66	3	r(t)d(t)−	r(t)d(t)−	PROPN
ijassa-998	66	4	kdr	kdr	PROPN
ijassa-998	66	5	a(t	a(t	PROPN
ijassa-998	66	6	)	)	PUNCT
ijassa-998	66	7	dat(t	dat(t	PROPN
ijassa-998	66	8	)	)	PUNCT
ijassa-998	66	9	dt	dt	NOUN
ijassa-998	67	1	=	=	SYM
ijassa-998	67	2	−λatat(t	−λatat(t	NOUN
ijassa-998	67	3	)	)	PUNCT
ijassa-998	68	1	+	+	CCONJ
ijassa-998	68	2	ktf	ktf	PROPN
ijassa-998	68	3	r(t)t	r(t)t	PROPN
ijassa-998	68	4	(	(	PUNCT
ijassa-998	68	5	t)−	t)−	PROPN
ijassa-998	68	6	ktr	ktr	PROPN
ijassa-998	68	7	at(t	at(t	NOUN
ijassa-998	68	8	)	)	PUNCT
ijassa-998	69	1	dp	dp	PROPN
ijassa-998	69	2	(	(	PUNCT
ijassa-998	69	3	t	t	NOUN
ijassa-998	69	4	)	)	PUNCT
ijassa-998	69	5	dt	dt	NOUN
ijassa-998	69	6	=	=	PUNCT
ijassa-998	69	7	βp(a(t	βp(a(t	X
ijassa-998	69	8	)	)	PUNCT
ijassa-998	69	9	+	+	NUM
ijassa-998	69	10	at(t	at(t	NUM
ijassa-998	69	11	)	)	PUNCT
ijassa-998	70	1	+	+	CCONJ
ijassa-998	70	2	ϕ)−	ϕ)−	PROPN
ijassa-998	70	3	αpp	αpp	PROPN
ijassa-998	70	4	(	(	PUNCT
ijassa-998	70	5	t)efrac	t)efrac	NOUN
ijassa-998	70	6	−	−	PROPN
ijassa-998	71	1	γpp	γpp	PROPN
ijassa-998	71	2	(	(	PUNCT
ijassa-998	71	3	t	t	NOUN
ijassa-998	71	4	)	)	PUNCT
ijassa-998	71	5	(	(	PUNCT
ijassa-998	71	6	m(t	m(t	NOUN
ijassa-998	71	7	)	)	PUNCT
ijassa-998	72	1	+	+	NUM
ijassa-998	72	2	n(t))2	n(t))2	NOUN
ijassa-998	72	3	kp	kp	NOUN
ijassa-998	72	4	+	+	CCONJ
ijassa-998	72	5	(	(	PUNCT
ijassa-998	72	6	m(t	m(t	X
ijassa-998	72	7	)	)	PUNCT
ijassa-998	72	8	+	+	VERB
ijassa-998	72	9	n(t	n(t	X
ijassa-998	72	10	)	)	PUNCT
ijassa-998	72	11	)	)	PUNCT
ijassa-998	73	1	−	−	PROPN
ijassa-998	73	2	λpp	λpp	ADJ
ijassa-998	73	3	(	(	PUNCT
ijassa-998	73	4	t	t	PROPN
ijassa-998	73	5	)	)	PUNCT
ijassa-998	73	6	t	t	PROPN
ijassa-998	73	7	∈	∈	PROPN
ijassa-998	74	1	[	[	X
ijassa-998	74	2	0	0	NUM
ijassa-998	74	3	,	,	PUNCT
ijassa-998	74	4	t	t	X
ijassa-998	74	5	]	]	PUNCT
ijassa-998	74	6	,	,	PUNCT
ijassa-998	74	7	e(0	e(0	NOUN
ijassa-998	74	8	)	)	PUNCT
ijassa-998	74	9	,	,	PUNCT
ijassa-998	74	10	n(0	n(0	PROPN
ijassa-998	74	11	)	)	PUNCT
ijassa-998	74	12	,	,	PUNCT
ijassa-998	74	13	m(0	m(0	PROPN
ijassa-998	74	14	)	)	PUNCT
ijassa-998	74	15	,	,	PUNCT
ijassa-998	74	16	r(0	r(0	PROPN
ijassa-998	74	17	)	)	PUNCT
ijassa-998	74	18	,	,	PUNCT
ijassa-998	74	19	d(0	d(0	PROPN
ijassa-998	74	20	)	)	PUNCT
ijassa-998	74	21	,	,	PUNCT
ijassa-998	74	22	t	t	PROPN
ijassa-998	74	23	(	(	PUNCT
ijassa-998	74	24	0	0	NUM
ijassa-998	74	25	)	)	PUNCT
ijassa-998	74	26	,	,	PUNCT
ijassa-998	74	27	a(0	a(0	PROPN
ijassa-998	74	28	)	)	PUNCT
ijassa-998	74	29	,	,	PUNCT
ijassa-998	74	30	at(0	at(0	PROPN
ijassa-998	74	31	)	)	PUNCT
ijassa-998	74	32	,	,	PUNCT
ijassa-998	74	33	p	p	X
ijassa-998	74	34	(	(	PUNCT
ijassa-998	74	35	0	0	NUM
ijassa-998	74	36	)	)	PUNCT
ijassa-998	74	37	∈	∈	PROPN
ijassa-998	74	38	r+	r+	NOUN
ijassa-998	74	39	,	,	PUNCT
ijassa-998	74	40	(	(	PUNCT
ijassa-998	74	41	2.1	2.1	NUM
ijassa-998	74	42	)	)	PUNCT
ijassa-998	74	43	where	where	SCONJ
ijassa-998	74	44	efrac	efrac	ADJ
ijassa-998	74	45	=	=	PUNCT
ijassa-998	74	46	vc	vc	X
ijassa-998	74	47	e	e	NOUN
ijassa-998	74	48	pv	pv	INTJ
ijassa-998	74	49	ol	ol	ADJ
ijassa-998	74	50	,	,	PUNCT
ijassa-998	74	51	pv	pv	INTJ
ijassa-998	74	52	ol	ol	ADJ
ijassa-998	74	53	=	=	PUNCT
ijassa-998	74	54	αvt	αvt	NOUN
ijassa-998	74	55	dv	dv	PROPN
ijassa-998	74	56	bdvv	bdvv	NOUN
ijassa-998	74	57	+	+	CCONJ
ijassa-998	74	58	tdv	tdv	NOUN
ijassa-998	74	59	.	.	PUNCT
ijassa-998	75	1	in	in	ADP
ijassa-998	75	2	(	(	PUNCT
ijassa-998	75	3	2.1	2.1	NUM
ijassa-998	75	4	)	)	PUNCT
ijassa-998	75	5	it	it	PRON
ijassa-998	75	6	is	be	AUX
ijassa-998	75	7	assumed	assume	VERB
ijassa-998	75	8	that	that	SCONJ
ijassa-998	75	9	the	the	DET
ijassa-998	75	10	healthy	healthy	ADJ
ijassa-998	75	11	cells	cell	NOUN
ijassa-998	75	12	e	e	X
ijassa-998	75	13	have	have	VERB
ijassa-998	75	14	the	the	DET
ijassa-998	75	15	proliferation	proliferation	NOUN
ijassa-998	75	16	rate	rate	NOUN
ijassa-998	75	17	µe	µe	ADP
ijassa-998	75	18	,	,	PUNCT
ijassa-998	75	19	the	the	DET
ijassa-998	75	20	death	death	NOUN
ijassa-998	75	21	rate	rate	NOUN
ijassa-998	75	22	δe	δe	NOUN
ijassa-998	75	23	and	and	CCONJ
ijassa-998	75	24	a	a	DET
ijassa-998	75	25	limit	limit	NOUN
ijassa-998	75	26	ηe	ηe	ADP
ijassa-998	75	27	.	.	PUNCT
ijassa-998	76	1	the	the	DET
ijassa-998	76	2	magnitude	magnitude	NOUN
ijassa-998	76	3	of	of	ADP
ijassa-998	76	4	the	the	DET
ijassa-998	76	5	competition	competition	NOUN
ijassa-998	76	6	between	between	ADP
ijassa-998	76	7	healthy	healthy	ADJ
ijassa-998	76	8	and	and	CCONJ
ijassa-998	76	9	cancer	cancer	NOUN
ijassa-998	76	10	cells	cell	NOUN
ijassa-998	76	11	is	be	AUX
ijassa-998	76	12	modelled	model	VERB
ijassa-998	76	13	by	by	ADP
ijassa-998	76	14	means	mean	NOUN
ijassa-998	76	15	of	of	ADP
ijassa-998	76	16	the	the	DET
ijassa-998	76	17	parameter	parameter	NOUN
ijassa-998	76	18	ε	ε	PROPN
ijassa-998	76	19	.	.	PUNCT
ijassa-998	77	1	the	the	DET
ijassa-998	77	2	androgen	androgen	NOUN
ijassa-998	77	3	-	-	PUNCT
ijassa-998	77	4	dependent	dependent	ADJ
ijassa-998	77	5	cancer	cancer	NOUN
ijassa-998	77	6	cells	cell	NOUN
ijassa-998	77	7	n	n	CCONJ
ijassa-998	77	8	proliferate	proliferate	VERB
ijassa-998	77	9	at	at	ADP
ijassa-998	77	10	rate	rate	NOUN
ijassa-998	77	11	µn	µn	NOUN
ijassa-998	77	12	,	,	PUNCT
ijassa-998	77	13	decease	decease	VERB
ijassa-998	77	14	with	with	ADP
ijassa-998	77	15	rate	rate	NOUN
ijassa-998	77	16	δn	δn	NOUN
ijassa-998	77	17	and	and	CCONJ
ijassa-998	77	18	have	have	VERB
ijassa-998	77	19	the	the	DET
ijassa-998	77	20	limit	limit	NOUN
ijassa-998	77	21	ηn	ηn	INTJ
ijassa-998	77	22	.	.	PUNCT
ijassa-998	78	1	with	with	SCONJ
ijassa-998	78	2	the	the	DET
ijassa-998	78	3	probability	probability	NOUN
ijassa-998	78	4	αm	αm	PROPN
ijassa-998	78	5	∈	∈	PROPN
ijassa-998	78	6	(	(	PUNCT
ijassa-998	78	7	0	0	NUM
ijassa-998	78	8	,	,	PUNCT
ijassa-998	78	9	1	1	X
ijassa-998	78	10	)	)	PUNCT
ijassa-998	78	11	cancer	cancer	NOUN
ijassa-998	78	12	cells	cell	NOUN
ijassa-998	78	13	n	n	PRON
ijassa-998	78	14	mutate	mutate	VERB
ijassa-998	78	15	to	to	ADP
ijassa-998	78	16	castrationresistant	castrationresistant	ADJ
ijassa-998	78	17	cancer	cancer	NOUN
ijassa-998	78	18	cells	cell	NOUN
ijassa-998	78	19	m	m	VERB
ijassa-998	78	20	where	where	SCONJ
ijassa-998	78	21	the	the	DET
ijassa-998	78	22	parameters	parameter	NOUN
ijassa-998	78	23	µm	µm	ADP
ijassa-998	78	24	and	and	CCONJ
ijassa-998	78	25	δm	δm	PROPN
ijassa-998	78	26	represent	represent	VERB
ijassa-998	78	27	the	the	DET
ijassa-998	78	28	proliferation	proliferation	NOUN
ijassa-998	78	29	and	and	CCONJ
ijassa-998	78	30	dead	dead	ADJ
ijassa-998	78	31	rate	rate	NOUN
ijassa-998	78	32	respectively	respectively	ADV
ijassa-998	78	33	.	.	PUNCT
ijassa-998	79	1	because	because	SCONJ
ijassa-998	79	2	of	of	ADP
ijassa-998	79	3	the	the	DET
ijassa-998	79	4	character	character	NOUN
ijassa-998	79	5	of	of	ADP
ijassa-998	79	6	this	this	DET
ijassa-998	79	7	article	article	NOUN
ijassa-998	79	8	the	the	DET
ijassa-998	79	9	remaining	remain	VERB
ijassa-998	79	10	state	state	NOUN
ijassa-998	79	11	variables	variable	NOUN
ijassa-998	79	12	of	of	ADP
ijassa-998	79	13	the	the	DET
ijassa-998	79	14	dynamic	dynamic	ADJ
ijassa-998	79	15	system	system	NOUN
ijassa-998	79	16	(	(	PUNCT
ijassa-998	79	17	2.1	2.1	NUM
ijassa-998	79	18	)	)	PUNCT
ijassa-998	79	19	which	which	PRON
ijassa-998	79	20	represent	represent	VERB
ijassa-998	79	21	specific	specific	ADJ
ijassa-998	79	22	hormone	hormone	NOUN
ijassa-998	79	23	levels	level	NOUN
ijassa-998	79	24	in	in	ADP
ijassa-998	79	25	the	the	DET
ijassa-998	79	26	organism	organism	NOUN
ijassa-998	79	27	are	be	AUX
ijassa-998	79	28	only	only	ADV
ijassa-998	79	29	mentioned	mention	VERB
ijassa-998	79	30	:	:	PUNCT
ijassa-998	79	31	t	t	X
ijassa-998	79	32	testosterone	testosterone	NOUN
ijassa-998	79	33	concentration	concentration	NOUN
ijassa-998	79	34	,	,	PUNCT
ijassa-998	79	35	p	p	NOUN
ijassa-998	79	36	tissue	tissue	NOUN
ijassa-998	79	37	psa	psa	NOUN
ijassa-998	79	38	concentration	concentration	NOUN
ijassa-998	79	39	,	,	PUNCT
ijassa-998	79	40	r	r	NOUN
ijassa-998	79	41	free	free	ADJ
ijassa-998	79	42	androgen	androgen	NOUN
ijassa-998	79	43	receptor	receptor	NOUN
ijassa-998	79	44	concentration	concentration	NOUN
ijassa-998	79	45	,	,	PUNCT
ijassa-998	79	46	d	d	DET
ijassa-998	79	47	dihydrotestosterone	dihydrotestosterone	NOUN
ijassa-998	79	48	concentration	concentration	NOUN
ijassa-998	79	49	,	,	PUNCT
ijassa-998	79	50	a	a	DET
ijassa-998	79	51	dihydrotestosterone	dihydrotestosterone	NOUN
ijassa-998	79	52	-	-	PUNCT
ijassa-998	79	53	activated	activate	VERB
ijassa-998	79	54	androgen	androgen	NOUN
ijassa-998	79	55	receptor	receptor	NOUN
ijassa-998	79	56	concentration	concentration	NOUN
ijassa-998	79	57	,	,	PUNCT
ijassa-998	79	58	at	at	ADP
ijassa-998	79	59	testosterone	testosterone	NOUN
ijassa-998	79	60	-	-	PUNCT
ijassa-998	79	61	activated	activate	VERB
ijassa-998	79	62	androgen	androgen	NOUN
ijassa-998	79	63	receptor	receptor	NOUN
ijassa-998	79	64	concentration	concentration	NOUN
ijassa-998	79	65	.	.	PUNCT
ijassa-998	80	1	in	in	ADP
ijassa-998	80	2	this	this	DET
ijassa-998	80	3	article	article	NOUN
ijassa-998	80	4	all	all	DET
ijassa-998	80	5	cell	cell	NOUN
ijassa-998	80	6	types	type	NOUN
ijassa-998	80	7	are	be	AUX
ijassa-998	80	8	estimated	estimate	VERB
ijassa-998	80	9	in	in	ADP
ijassa-998	80	10	billions	billion	NOUN
ijassa-998	80	11	.	.	PUNCT
ijassa-998	81	1	detailed	detailed	ADJ
ijassa-998	81	2	information	information	NOUN
ijassa-998	81	3	,	,	PUNCT
ijassa-998	81	4	the	the	DET
ijassa-998	81	5	biological	biological	ADJ
ijassa-998	81	6	background	background	NOUN
ijassa-998	81	7	of	of	ADP
ijassa-998	81	8	the	the	DET
ijassa-998	81	9	variables	variable	NOUN
ijassa-998	81	10	and	and	CCONJ
ijassa-998	81	11	the	the	DET
ijassa-998	81	12	associated	associated	ADJ
ijassa-998	81	13	parameters	parameter	NOUN
ijassa-998	81	14	are	be	AUX
ijassa-998	81	15	given	give	VERB
ijassa-998	81	16	in	in	ADP
ijassa-998	81	17	[	[	X
ijassa-998	81	18	?	?	PUNCT
ijassa-998	81	19	]	]	PUNCT
ijassa-998	81	20	.	.	PUNCT
ijassa-998	82	1	assuming	assume	VERB
ijassa-998	82	2	µn	µn	PROPN
ijassa-998	82	3	=	=	SYM
ijassa-998	82	4	µm	µm	X
ijassa-998	82	5	=	=	SYM
ijassa-998	82	6	µ	µ	X
ijassa-998	82	7	,	,	PUNCT
ijassa-998	82	8	δn	δn	NOUN
ijassa-998	82	9	=	=	PUNCT
ijassa-998	82	10	δm	δm	PROPN
ijassa-998	82	11	=	=	PROPN
ijassa-998	82	12	δ	δ	PROPN
ijassa-998	82	13	,	,	PUNCT
ijassa-998	82	14	n(t	n(t	PROPN
ijassa-998	82	15	)	)	PUNCT
ijassa-998	82	16	and	and	CCONJ
ijassa-998	82	17	m(t	m(t	NOUN
ijassa-998	82	18	)	)	PUNCT
ijassa-998	82	19	can	can	AUX
ijassa-998	82	20	be	be	AUX
ijassa-998	82	21	substituted	substitute	VERB
ijassa-998	82	22	in	in	ADP
ijassa-998	82	23	order	order	NOUN
ijassa-998	82	24	to	to	PART
ijassa-998	82	25	represent	represent	VERB
ijassa-998	82	26	the	the	DET
ijassa-998	82	27	total	total	ADJ
ijassa-998	82	28	number	number	NOUN
ijassa-998	82	29	of	of	ADP
ijassa-998	82	30	the	the	DET
ijassa-998	82	31	prostate	prostate	NOUN
ijassa-998	82	32	cancer	cancer	NOUN
ijassa-998	82	33	cells	cell	NOUN
ijassa-998	82	34	.	.	PUNCT
ijassa-998	83	1	from	from	ADP
ijassa-998	83	2	the	the	DET
ijassa-998	83	3	addition	addition	NOUN
ijassa-998	83	4	n(t	n(t	NOUN
ijassa-998	83	5	)	)	PUNCT
ijassa-998	83	6	+	+	NOUN
ijassa-998	83	7	m(t	m(t	X
ijassa-998	83	8	)	)	PUNCT
ijassa-998	83	9	=	=	PUNCT
ijassa-998	83	10	z(t	z(t	NOUN
ijassa-998	83	11	)	)	PUNCT
ijassa-998	83	12	follows	follow	VERB
ijassa-998	83	13	dz(t	dz(t	NOUN
ijassa-998	83	14	)	)	PUNCT
ijassa-998	83	15	dt	dt	X
ijassa-998	84	1	=	=	SYM
ijassa-998	84	2	µz(t	µz(t	X
ijassa-998	84	3	)	)	PUNCT
ijassa-998	84	4	(	(	PUNCT
ijassa-998	84	5	1−	1−	NUM
ijassa-998	84	6	z(t	z(t	NOUN
ijassa-998	84	7	)	)	PUNCT
ijassa-998	84	8	η	η	PROPN
ijassa-998	84	9	)	)	PUNCT
ijassa-998	84	10	−	−	PROPN
ijassa-998	85	1	δz(t	δz(t	NOUN
ijassa-998	85	2	)	)	PUNCT
ijassa-998	85	3	.	.	PUNCT
ijassa-998	86	1	(	(	PUNCT
ijassa-998	86	2	2.2	2.2	NUM
ijassa-998	86	3	)	)	PUNCT
ijassa-998	86	4	the	the	DET
ijassa-998	86	5	following	follow	VERB
ijassa-998	86	6	figures	figure	NOUN
ijassa-998	86	7	illustrate	illustrate	VERB
ijassa-998	86	8	the	the	DET
ijassa-998	86	9	behaviour	behaviour	NOUN
ijassa-998	86	10	of	of	ADP
ijassa-998	86	11	healthy	healthy	ADJ
ijassa-998	86	12	and	and	CCONJ
ijassa-998	86	13	cancer	cancer	NOUN
ijassa-998	86	14	cells	cell	NOUN
ijassa-998	86	15	as	as	ADV
ijassa-998	86	16	well	well	ADV
ijassa-998	86	17	as	as	ADP
ijassa-998	86	18	the	the	DET
ijassa-998	86	19	psa	psa	NOUN
ijassa-998	86	20	-	-	PUNCT
ijassa-998	86	21	level	level	NOUN
ijassa-998	86	22	in	in	ADP
ijassa-998	86	23	the	the	DET
ijassa-998	86	24	absence	absence	NOUN
ijassa-998	86	25	of	of	ADP
ijassa-998	86	26	therapy	therapy	NOUN
ijassa-998	86	27	.	.	PUNCT
ijassa-998	87	1	the	the	DET
ijassa-998	87	2	parameters	parameter	NOUN
ijassa-998	87	3	of	of	ADP
ijassa-998	87	4	the	the	DET
ijassa-998	87	5	model	model	NOUN
ijassa-998	87	6	which	which	PRON
ijassa-998	87	7	were	be	AUX
ijassa-998	87	8	used	use	VERB
ijassa-998	87	9	in	in	ADP
ijassa-998	87	10	this	this	DET
ijassa-998	87	11	copyright	copyright	NOUN
ijassa-998	87	12	c	c	ADP
ijassa-998	87	13	©	©	PROPN
ijassa-998	87	14	2020	2020	NUM
ijassa-998	87	15	assa	assa	NOUN
ijassa-998	87	16	.	.	PUNCT
ijassa-998	88	1	adv	adv	PROPN
ijassa-998	88	2	syst	syst	PROPN
ijassa-998	88	3	sci	sci	PROPN
ijassa-998	88	4	appl	appl	PROPN
ijassa-998	88	5	(	(	PUNCT
ijassa-998	88	6	2020	2020	NUM
ijassa-998	88	7	)	)	PUNCT
ijassa-998	88	8	86	86	NUM
ijassa-998	88	9	m.-c	m.-c	NOUN
ijassa-998	88	10	.	.	PUNCT
ijassa-998	89	1	litzinger	litzinger	NOUN
ijassa-998	89	2	,	,	PUNCT
ijassa-998	89	3	y.	y.	PROPN
ijassa-998	89	4	todorov	todorov	PROPN
ijassa-998	89	5	,	,	PUNCT
ijassa-998	89	6	m.	m.	NOUN
ijassa-998	89	7	föller	föller	PROPN
ijassa-998	89	8	-	-	PUNCT
ijassa-998	89	9	nord	nord	PROPN
ijassa-998	89	10	,	,	PUNCT
ijassa-998	89	11	m.k	m.k	PROPN
ijassa-998	89	12	.	.	PUNCT
ijassa-998	89	13	chaudhary	chaudhary	PROPN
ijassa-998	89	14	,	,	PUNCT
ijassa-998	89	15	a.s	a.s	PROPN
ijassa-998	89	16	.	.	PROPN
ijassa-998	89	17	bratus	bratus	PROPN
ijassa-998	89	18	article	article	NOUN
ijassa-998	89	19	describe	describe	VERB
ijassa-998	89	20	a	a	DET
ijassa-998	89	21	scenario	scenario	NOUN
ijassa-998	89	22	in	in	ADP
ijassa-998	89	23	which	which	PRON
ijassa-998	89	24	the	the	DET
ijassa-998	89	25	amount	amount	NOUN
ijassa-998	89	26	of	of	ADP
ijassa-998	89	27	healthy	healthy	ADJ
ijassa-998	89	28	cells	cell	NOUN
ijassa-998	89	29	is	be	AUX
ijassa-998	89	30	not	not	PART
ijassa-998	89	31	strongly	strongly	ADV
ijassa-998	89	32	influenced	influence	VERB
ijassa-998	89	33	by	by	ADP
ijassa-998	89	34	cancer	cancer	NOUN
ijassa-998	89	35	cells	cell	NOUN
ijassa-998	89	36	.	.	PUNCT
ijassa-998	90	1	the	the	DET
ijassa-998	90	2	set	set	NOUN
ijassa-998	90	3	of	of	ADP
ijassa-998	90	4	parameters	parameter	NOUN
ijassa-998	90	5	and	and	CCONJ
ijassa-998	90	6	their	their	PRON
ijassa-998	90	7	description	description	NOUN
ijassa-998	90	8	is	be	AUX
ijassa-998	90	9	given	give	VERB
ijassa-998	90	10	(	(	PUNCT
ijassa-998	90	11	see	see	VERB
ijassa-998	90	12	a.1	a.1	NOUN
ijassa-998	90	13	)	)	PUNCT
ijassa-998	90	14	.	.	PUNCT
ijassa-998	91	1	0	0	NUM
ijassa-998	91	2	50	50	NUM
ijassa-998	91	3	100	100	NUM
ijassa-998	91	4	150	150	NUM
ijassa-998	91	5	non	non	ADJ
ijassa-998	91	6	-	-	ADJ
ijassa-998	91	7	dimensional	dimensional	ADJ
ijassa-998	91	8	time	time	NOUN
ijassa-998	91	9	0	0	NUM
ijassa-998	91	10	50	50	NUM
ijassa-998	91	11	100	100	NUM
ijassa-998	91	12	150	150	NUM
ijassa-998	91	13	200	200	NUM
ijassa-998	91	14	250	250	NUM
ijassa-998	91	15	300	300	NUM
ijassa-998	91	16	fig	fig	NOUN
ijassa-998	91	17	.	.	PUNCT
ijassa-998	92	1	2.1	2.1	NUM
ijassa-998	92	2	.	.	PUNCT
ijassa-998	92	3	time	time	NOUN
ijassa-998	92	4	response	response	NOUN
ijassa-998	92	5	of	of	ADP
ijassa-998	92	6	healthy	healthy	ADJ
ijassa-998	92	7	e(t	e(t	NOUN
ijassa-998	92	8	)	)	PUNCT
ijassa-998	92	9	and	and	CCONJ
ijassa-998	92	10	cancer	cancer	NOUN
ijassa-998	92	11	cells	cell	NOUN
ijassa-998	92	12	z(t	z(t	NOUN
ijassa-998	92	13	)	)	PUNCT
ijassa-998	92	14	0	0	NUM
ijassa-998	93	1	50	50	NUM
ijassa-998	93	2	100	100	NUM
ijassa-998	93	3	150	150	NUM
ijassa-998	93	4	non	non	ADJ
ijassa-998	93	5	-	-	ADJ
ijassa-998	93	6	dimensional	dimensional	ADJ
ijassa-998	93	7	time	time	NOUN
ijassa-998	93	8	0	0	NUM
ijassa-998	93	9	1	1	NUM
ijassa-998	93	10	2	2	NUM
ijassa-998	93	11	3	3	NUM
ijassa-998	93	12	4	4	NUM
ijassa-998	93	13	5	5	NUM
ijassa-998	93	14	6	6	NUM
ijassa-998	93	15	7	7	NUM
ijassa-998	93	16	8	8	NUM
ijassa-998	93	17	9	9	NUM
ijassa-998	93	18	10	10	NUM
ijassa-998	93	19	fig	fig	NOUN
ijassa-998	93	20	.	.	PUNCT
ijassa-998	94	1	2.2	2.2	NUM
ijassa-998	94	2	.	.	PUNCT
ijassa-998	94	3	time	time	NOUN
ijassa-998	94	4	response	response	NOUN
ijassa-998	94	5	of	of	ADP
ijassa-998	94	6	the	the	DET
ijassa-998	94	7	psa	psa	NOUN
ijassa-998	94	8	function	function	PROPN
ijassa-998	94	9	p	p	PROPN
ijassa-998	94	10	(	(	PUNCT
ijassa-998	94	11	t	t	NOUN
ijassa-998	94	12	)	)	PUNCT
ijassa-998	94	13	copyright	copyright	NOUN
ijassa-998	94	14	c	c	ADP
ijassa-998	94	15	©	©	PROPN
ijassa-998	94	16	2020	2020	NUM
ijassa-998	94	17	assa	assa	NOUN
ijassa-998	94	18	.	.	PUNCT
ijassa-998	95	1	adv	adv	PROPN
ijassa-998	95	2	syst	syst	PROPN
ijassa-998	95	3	sci	sci	PROPN
ijassa-998	95	4	appl	appl	PROPN
ijassa-998	95	5	(	(	PUNCT
ijassa-998	95	6	2020	2020	NUM
ijassa-998	95	7	)	)	PUNCT
ijassa-998	95	8	on	on	ADP
ijassa-998	95	9	optimal	optimal	ADJ
ijassa-998	95	10	therapy	therapy	NOUN
ijassa-998	95	11	protocols	protocol	NOUN
ijassa-998	95	12	in	in	ADP
ijassa-998	95	13	the	the	DET
ijassa-998	95	14	math	math	NOUN
ijassa-998	95	15	.	.	PUNCT
ijassa-998	96	1	model	model	NOUN
ijassa-998	96	2	of	of	ADP
ijassa-998	96	3	prostate	prostate	NOUN
ijassa-998	96	4	cancer	cancer	NOUN
ijassa-998	96	5	progression	progression	NOUN
ijassa-998	96	6	87	87	NUM
ijassa-998	96	7	as	as	SCONJ
ijassa-998	96	8	mentioned	mention	VERB
ijassa-998	96	9	before	before	ADP
ijassa-998	96	10	intermittent	intermittent	PROPN
ijassa-998	96	11	therapy	therapy	NOUN
ijassa-998	96	12	is	be	AUX
ijassa-998	96	13	one	one	NUM
ijassa-998	96	14	way	way	NOUN
ijassa-998	96	15	to	to	PART
ijassa-998	96	16	slow	slow	VERB
ijassa-998	96	17	down	down	ADP
ijassa-998	96	18	the	the	DET
ijassa-998	96	19	development	development	NOUN
ijassa-998	96	20	of	of	ADP
ijassa-998	96	21	therapy	therapy	NOUN
ijassa-998	96	22	resistance	resistance	NOUN
ijassa-998	96	23	.	.	PUNCT
ijassa-998	97	1	the	the	DET
ijassa-998	97	2	following	follow	VERB
ijassa-998	97	3	figures	figure	NOUN
ijassa-998	97	4	show	show	VERB
ijassa-998	97	5	the	the	DET
ijassa-998	97	6	dynamics	dynamic	NOUN
ijassa-998	97	7	of	of	ADP
ijassa-998	97	8	the	the	DET
ijassa-998	97	9	system	system	NOUN
ijassa-998	97	10	when	when	SCONJ
ijassa-998	97	11	such	such	ADJ
ijassa-998	97	12	therapy	therapy	NOUN
ijassa-998	97	13	is	be	AUX
ijassa-998	97	14	applied	apply	VERB
ijassa-998	97	15	.	.	PUNCT
ijassa-998	98	1	0	0	NUM
ijassa-998	98	2	50	50	NUM
ijassa-998	98	3	100	100	NUM
ijassa-998	98	4	150	150	NUM
ijassa-998	98	5	non	non	ADJ
ijassa-998	98	6	-	-	ADJ
ijassa-998	98	7	dimensional	dimensional	ADJ
ijassa-998	98	8	time	time	NOUN
ijassa-998	98	9	0	0	NUM
ijassa-998	98	10	1	1	NUM
ijassa-998	98	11	2	2	NUM
ijassa-998	98	12	3	3	NUM
ijassa-998	98	13	4	4	NUM
ijassa-998	98	14	5	5	NUM
ijassa-998	98	15	fig	fig	NOUN
ijassa-998	98	16	.	.	PUNCT
ijassa-998	99	1	2.3	2.3	NUM
ijassa-998	99	2	.	.	PUNCT
ijassa-998	99	3	amount	amount	NOUN
ijassa-998	99	4	of	of	ADP
ijassa-998	99	5	the	the	DET
ijassa-998	99	6	administered	administer	VERB
ijassa-998	99	7	drug	drug	NOUN
ijassa-998	99	8	u(t	u(t	NOUN
ijassa-998	99	9	)	)	PUNCT
ijassa-998	99	10	0	0	NUM
ijassa-998	99	11	50	50	NUM
ijassa-998	99	12	100	100	NUM
ijassa-998	99	13	150	150	NUM
ijassa-998	99	14	non	non	ADJ
ijassa-998	99	15	-	-	ADJ
ijassa-998	99	16	dimensional	dimensional	ADJ
ijassa-998	99	17	time	time	NOUN
ijassa-998	99	18	0	0	NUM
ijassa-998	99	19	50	50	NUM
ijassa-998	99	20	100	100	NUM
ijassa-998	99	21	150	150	NUM
ijassa-998	99	22	200	200	NUM
ijassa-998	99	23	250	250	NUM
ijassa-998	99	24	300	300	NUM
ijassa-998	99	25	fig	fig	NOUN
ijassa-998	99	26	.	.	PUNCT
ijassa-998	100	1	2.4	2.4	NUM
ijassa-998	100	2	.	.	PUNCT
ijassa-998	100	3	time	time	NOUN
ijassa-998	100	4	response	response	NOUN
ijassa-998	100	5	of	of	ADP
ijassa-998	100	6	healthy	healthy	ADJ
ijassa-998	100	7	e(t	e(t	NOUN
ijassa-998	100	8	)	)	PUNCT
ijassa-998	100	9	and	and	CCONJ
ijassa-998	100	10	cancer	cancer	NOUN
ijassa-998	100	11	cells	cell	NOUN
ijassa-998	100	12	z(t	z(t	NOUN
ijassa-998	100	13	)	)	PUNCT
ijassa-998	100	14	copyright	copyright	NOUN
ijassa-998	100	15	c	c	ADP
ijassa-998	100	16	©	©	PROPN
ijassa-998	100	17	2020	2020	NUM
ijassa-998	100	18	assa	assa	NOUN
ijassa-998	100	19	.	.	PUNCT
ijassa-998	101	1	adv	adv	PROPN
ijassa-998	101	2	syst	syst	PROPN
ijassa-998	101	3	sci	sci	PROPN
ijassa-998	101	4	appl	appl	PROPN
ijassa-998	101	5	(	(	PUNCT
ijassa-998	101	6	2020	2020	NUM
ijassa-998	101	7	)	)	PUNCT
ijassa-998	101	8	88	88	NUM
ijassa-998	101	9	m.-c	m.-c	NOUN
ijassa-998	101	10	.	.	PUNCT
ijassa-998	102	1	litzinger	litzinger	NOUN
ijassa-998	102	2	,	,	PUNCT
ijassa-998	102	3	y.	y.	PROPN
ijassa-998	102	4	todorov	todorov	PROPN
ijassa-998	102	5	,	,	PUNCT
ijassa-998	102	6	m.	m.	NOUN
ijassa-998	102	7	föller	föller	PROPN
ijassa-998	102	8	-	-	PUNCT
ijassa-998	102	9	nord	nord	PROPN
ijassa-998	102	10	,	,	PUNCT
ijassa-998	102	11	m.k	m.k	PROPN
ijassa-998	102	12	.	.	PUNCT
ijassa-998	102	13	chaudhary	chaudhary	PROPN
ijassa-998	102	14	,	,	PUNCT
ijassa-998	102	15	a.s	a.s	PROPN
ijassa-998	102	16	.	.	PROPN
ijassa-998	102	17	bratus	bratus	PROPN
ijassa-998	102	18	0	0	NUM
ijassa-998	102	19	50	50	NUM
ijassa-998	102	20	100	100	NUM
ijassa-998	102	21	150	150	NUM
ijassa-998	102	22	non	non	ADJ
ijassa-998	102	23	-	-	ADJ
ijassa-998	102	24	dimensional	dimensional	ADJ
ijassa-998	102	25	time	time	NOUN
ijassa-998	102	26	0	0	NUM
ijassa-998	102	27	1	1	NUM
ijassa-998	102	28	2	2	NUM
ijassa-998	102	29	3	3	NUM
ijassa-998	102	30	4	4	NUM
ijassa-998	102	31	5	5	NUM
ijassa-998	102	32	6	6	NUM
ijassa-998	102	33	7	7	NUM
ijassa-998	102	34	8	8	NUM
ijassa-998	102	35	9	9	NUM
ijassa-998	102	36	10	10	NUM
ijassa-998	102	37	fig	fig	NOUN
ijassa-998	102	38	.	.	PUNCT
ijassa-998	103	1	2.5	2.5	NUM
ijassa-998	103	2	.	.	PUNCT
ijassa-998	103	3	time	time	NOUN
ijassa-998	103	4	response	response	NOUN
ijassa-998	103	5	of	of	ADP
ijassa-998	103	6	the	the	DET
ijassa-998	103	7	psa	psa	NOUN
ijassa-998	103	8	function	function	PROPN
ijassa-998	103	9	p	p	PROPN
ijassa-998	103	10	(	(	PUNCT
ijassa-998	103	11	t	t	PROPN
ijassa-998	103	12	)	)	PUNCT
ijassa-998	103	13	in	in	ADP
ijassa-998	103	14	the	the	DET
ijassa-998	103	15	following	follow	VERB
ijassa-998	103	16	sections	section	NOUN
ijassa-998	103	17	different	different	ADJ
ijassa-998	103	18	therapy	therapy	NOUN
ijassa-998	103	19	strategies	strategy	NOUN
ijassa-998	103	20	are	be	AUX
ijassa-998	103	21	determined	determine	VERB
ijassa-998	103	22	and	and	CCONJ
ijassa-998	103	23	used	use	VERB
ijassa-998	103	24	to	to	PART
ijassa-998	103	25	minimize	minimize	VERB
ijassa-998	103	26	cancer	cancer	NOUN
ijassa-998	103	27	cells	cell	NOUN
ijassa-998	103	28	without	without	ADP
ijassa-998	103	29	violating	violate	VERB
ijassa-998	103	30	the	the	DET
ijassa-998	103	31	constraint	constraint	NOUN
ijassa-998	103	32	boundary	boundary	NOUN
ijassa-998	103	33	on	on	ADP
ijassa-998	103	34	healthy	healthy	ADJ
ijassa-998	103	35	cells	cell	NOUN
ijassa-998	103	36	.	.	PUNCT
ijassa-998	104	1	3	3	X
ijassa-998	104	2	.	.	X
ijassa-998	104	3	an	an	DET
ijassa-998	104	4	alternative	alternative	ADJ
ijassa-998	104	5	therapy	therapy	NOUN
ijassa-998	104	6	strategy	strategy	NOUN
ijassa-998	104	7	consider	consider	VERB
ijassa-998	104	8	the	the	DET
ijassa-998	104	9	optimal	optimal	ADJ
ijassa-998	104	10	control	control	NOUN
ijassa-998	104	11	problem	problem	NOUN
ijassa-998	104	12	after	after	ADP
ijassa-998	104	13	the	the	DET
ijassa-998	104	14	substitution	substitution	NOUN
ijassa-998	104	15	(	(	PUNCT
ijassa-998	104	16	2.2	2.2	NUM
ijassa-998	104	17	)	)	PUNCT
ijassa-998	105	1	min	min	NOUN
ijassa-998	105	2	u	u	PROPN
ijassa-998	105	3	j	j	PROPN
ijassa-998	105	4	=	=	SYM
ijassa-998	105	5	∫	∫	PROPN
ijassa-998	105	6	t	t	PROPN
ijassa-998	105	7	0	0	PROPN
ijassa-998	105	8	z(t)dt→	z(t)dt→	PROPN
ijassa-998	105	9	min	min	PROPN
ijassa-998	105	10	(	(	PUNCT
ijassa-998	105	11	3.3	3.3	NUM
ijassa-998	105	12	)	)	PUNCT
ijassa-998	105	13	copyright	copyright	NOUN
ijassa-998	105	14	c	c	ADP
ijassa-998	105	15	©	©	PROPN
ijassa-998	105	16	2020	2020	NUM
ijassa-998	105	17	assa	assa	NOUN
ijassa-998	105	18	.	.	PUNCT
ijassa-998	106	1	adv	adv	PROPN
ijassa-998	106	2	syst	syst	PROPN
ijassa-998	106	3	sci	sci	PROPN
ijassa-998	106	4	appl	appl	PROPN
ijassa-998	106	5	(	(	PUNCT
ijassa-998	106	6	2020	2020	NUM
ijassa-998	106	7	)	)	PUNCT
ijassa-998	106	8	on	on	ADP
ijassa-998	106	9	optimal	optimal	ADJ
ijassa-998	106	10	therapy	therapy	NOUN
ijassa-998	106	11	protocols	protocol	NOUN
ijassa-998	106	12	in	in	ADP
ijassa-998	106	13	the	the	DET
ijassa-998	106	14	math	math	NOUN
ijassa-998	106	15	.	.	PUNCT
ijassa-998	107	1	model	model	NOUN
ijassa-998	107	2	of	of	ADP
ijassa-998	107	3	prostate	prostate	NOUN
ijassa-998	107	4	cancer	cancer	NOUN
ijassa-998	107	5	progression	progression	NOUN
ijassa-998	107	6	89	89	NUM
ijassa-998	107	7	de(t	de(t	NUM
ijassa-998	107	8	)	)	PUNCT
ijassa-998	107	9	dt	dt	NOUN
ijassa-998	108	1	=	=	SYM
ijassa-998	108	2	µee(t	µee(t	PROPN
ijassa-998	108	3	)	)	PUNCT
ijassa-998	108	4	(	(	PUNCT
ijassa-998	108	5	1−	1−	NUM
ijassa-998	108	6	e(t	e(t	NOUN
ijassa-998	108	7	)	)	PUNCT
ijassa-998	108	8	ηe	ηe	ADP
ijassa-998	108	9	)	)	PUNCT
ijassa-998	108	10	−	−	PROPN
ijassa-998	108	11	εe(t)(m(t	εe(t)(m(t	NOUN
ijassa-998	108	12	)	)	PUNCT
ijassa-998	109	1	+	+	NOUN
ijassa-998	109	2	n(t	n(t	X
ijassa-998	109	3	)	)	PUNCT
ijassa-998	109	4	)	)	PUNCT
ijassa-998	109	5	ηe	ηe	ADP
ijassa-998	109	6	−	−	PROPN
ijassa-998	109	7	δee(t	δee(t	NOUN
ijassa-998	109	8	)	)	PUNCT
ijassa-998	109	9	dz(t	dz(t	NOUN
ijassa-998	109	10	)	)	PUNCT
ijassa-998	109	11	dt	dt	X
ijassa-998	109	12	=	=	SYM
ijassa-998	109	13	µ(h)z(t	µ(h)z(t	PROPN
ijassa-998	109	14	)	)	PUNCT
ijassa-998	109	15	(	(	PUNCT
ijassa-998	109	16	1−	1−	NUM
ijassa-998	109	17	z(t	z(t	NOUN
ijassa-998	109	18	)	)	PUNCT
ijassa-998	109	19	η	η	PROPN
ijassa-998	109	20	)	)	PUNCT
ijassa-998	109	21	−	−	ADP
ijassa-998	109	22	δz(t	δz(t	NOUN
ijassa-998	109	23	)	)	PUNCT
ijassa-998	109	24	dr(t	dr(t	NOUN
ijassa-998	109	25	)	)	PUNCT
ijassa-998	109	26	dt	dt	NOUN
ijassa-998	110	1	=	=	SYM
ijassa-998	110	2	αr	αr	PROPN
ijassa-998	110	3	−	−	PROPN
ijassa-998	110	4	λrr(t)−	λrr(t)−	PROPN
ijassa-998	110	5	kdf	kdf	PROPN
ijassa-998	110	6	r(t)d(t	r(t)d(t	NOUN
ijassa-998	110	7	)	)	PUNCT
ijassa-998	110	8	+	+	CCONJ
ijassa-998	110	9	kdr	kdr	PROPN
ijassa-998	110	10	a(t)−	a(t)−	PROPN
ijassa-998	110	11	ktf	ktf	PROPN
ijassa-998	110	12	r(t)t	r(t)t	PROPN
ijassa-998	110	13	(	(	PUNCT
ijassa-998	110	14	t	t	PROPN
ijassa-998	110	15	)	)	PUNCT
ijassa-998	111	1	+	+	CCONJ
ijassa-998	111	2	ktr	ktr	PROPN
ijassa-998	111	3	a(t	a(t	NOUN
ijassa-998	111	4	)	)	PUNCT
ijassa-998	111	5	dd(t	dd(t	NOUN
ijassa-998	111	6	)	)	PUNCT
ijassa-998	111	7	dt	dt	NOUN
ijassa-998	112	1	=	=	PUNCT
ijassa-998	112	2	βt	βt	PROPN
ijassa-998	112	3	t	t	PROPN
ijassa-998	112	4	(	(	PUNCT
ijassa-998	112	5	t	t	PROPN
ijassa-998	112	6	)	)	PUNCT
ijassa-998	112	7	kt	kt	PROPN
ijassa-998	113	1	+	+	PROPN
ijassa-998	113	2	t	t	PROPN
ijassa-998	113	3	(	(	PUNCT
ijassa-998	113	4	t	t	PROPN
ijassa-998	113	5	)	)	PUNCT
ijassa-998	113	6	−	−	PROPN
ijassa-998	114	1	λdd(t)−	λdd(t)−	PROPN
ijassa-998	114	2	kdf	kdf	PROPN
ijassa-998	114	3	r(t)d(t	r(t)d(t	NUM
ijassa-998	114	4	)	)	PUNCT
ijassa-998	114	5	+	+	CCONJ
ijassa-998	114	6	kdr	kdr	PROPN
ijassa-998	114	7	a(t	a(t	PROPN
ijassa-998	114	8	)	)	PUNCT
ijassa-998	114	9	dt	dt	X
ijassa-998	114	10	(	(	PUNCT
ijassa-998	114	11	t	t	NOUN
ijassa-998	114	12	)	)	PUNCT
ijassa-998	114	13	dt	dt	NOUN
ijassa-998	115	1	=	=	PUNCT
ijassa-998	115	2	f(ts)−	f(ts)−	X
ijassa-998	116	1	λtt	λtt	PROPN
ijassa-998	116	2	(	(	PUNCT
ijassa-998	116	3	t)−	t)−	PROPN
ijassa-998	116	4	βt	βt	X
ijassa-998	116	5	(	(	PUNCT
ijassa-998	116	6	t	t	PROPN
ijassa-998	116	7	)	)	PUNCT
ijassa-998	116	8	t	t	PROPN
ijassa-998	116	9	(	(	PUNCT
ijassa-998	116	10	t	t	PROPN
ijassa-998	116	11	)	)	PUNCT
ijassa-998	116	12	kt	kt	PROPN
ijassa-998	116	13	+	+	PROPN
ijassa-998	116	14	t	t	PROPN
ijassa-998	116	15	(	(	PUNCT
ijassa-998	116	16	t	t	PROPN
ijassa-998	116	17	)	)	PUNCT
ijassa-998	116	18	−	−	PROPN
ijassa-998	117	1	ktf	ktf	PROPN
ijassa-998	117	2	r(t)t	r(t)t	PROPN
ijassa-998	117	3	(	(	PUNCT
ijassa-998	117	4	t	t	PROPN
ijassa-998	117	5	)	)	PUNCT
ijassa-998	118	1	+	+	CCONJ
ijassa-998	118	2	ktr	ktr	PROPN
ijassa-998	118	3	at(t	at(t	NOUN
ijassa-998	118	4	)	)	PUNCT
ijassa-998	118	5	da(t	da(t	NOUN
ijassa-998	118	6	)	)	PUNCT
ijassa-998	118	7	dt	dt	NOUN
ijassa-998	119	1	=	=	SYM
ijassa-998	119	2	−λaa(t	−λaa(t	PROPN
ijassa-998	119	3	)	)	PUNCT
ijassa-998	120	1	+	+	CCONJ
ijassa-998	120	2	kdf	kdf	PROPN
ijassa-998	120	3	r(t)d(t)−	r(t)d(t)−	PROPN
ijassa-998	120	4	kdr	kdr	PROPN
ijassa-998	120	5	a(t	a(t	PROPN
ijassa-998	120	6	)	)	PUNCT
ijassa-998	120	7	dat(t	dat(t	PROPN
ijassa-998	120	8	)	)	PUNCT
ijassa-998	120	9	dt	dt	NOUN
ijassa-998	121	1	=	=	SYM
ijassa-998	121	2	−λatat(t	−λatat(t	NOUN
ijassa-998	121	3	)	)	PUNCT
ijassa-998	122	1	+	+	CCONJ
ijassa-998	122	2	ktf	ktf	PROPN
ijassa-998	122	3	r(t)t	r(t)t	PROPN
ijassa-998	122	4	(	(	PUNCT
ijassa-998	122	5	t)−	t)−	PROPN
ijassa-998	122	6	ktr	ktr	PROPN
ijassa-998	122	7	at(t	at(t	NOUN
ijassa-998	122	8	)	)	PUNCT
ijassa-998	123	1	dp	dp	PROPN
ijassa-998	123	2	(	(	PUNCT
ijassa-998	123	3	t	t	NOUN
ijassa-998	123	4	)	)	PUNCT
ijassa-998	123	5	dt	dt	NOUN
ijassa-998	123	6	=	=	PUNCT
ijassa-998	123	7	βp(a(t	βp(a(t	X
ijassa-998	123	8	)	)	PUNCT
ijassa-998	123	9	+	+	NUM
ijassa-998	123	10	at(t	at(t	NUM
ijassa-998	123	11	)	)	PUNCT
ijassa-998	124	1	+	+	CCONJ
ijassa-998	124	2	ϕ)−	ϕ)−	PROPN
ijassa-998	124	3	αpp	αpp	PROPN
ijassa-998	124	4	(	(	PUNCT
ijassa-998	124	5	t)efrac	t)efrac	NOUN
ijassa-998	124	6	−	−	PROPN
ijassa-998	125	1	γpp	γpp	PROPN
ijassa-998	125	2	(	(	PUNCT
ijassa-998	125	3	t	t	NOUN
ijassa-998	125	4	)	)	PUNCT
ijassa-998	125	5	(	(	PUNCT
ijassa-998	125	6	m(t	m(t	NOUN
ijassa-998	125	7	)	)	PUNCT
ijassa-998	126	1	+	+	NUM
ijassa-998	126	2	n(t))2	n(t))2	NOUN
ijassa-998	126	3	kp	kp	NOUN
ijassa-998	126	4	+	+	CCONJ
ijassa-998	126	5	(	(	PUNCT
ijassa-998	126	6	m(t	m(t	X
ijassa-998	126	7	)	)	PUNCT
ijassa-998	126	8	+	+	VERB
ijassa-998	126	9	n(t	n(t	X
ijassa-998	126	10	)	)	PUNCT
ijassa-998	126	11	)	)	PUNCT
ijassa-998	127	1	−	−	PROPN
ijassa-998	127	2	λpp	λpp	PROPN
ijassa-998	127	3	(	(	PUNCT
ijassa-998	127	4	t	t	NOUN
ijassa-998	127	5	)	)	PUNCT
ijassa-998	127	6	dh(t	dh(t	X
ijassa-998	127	7	)	)	PUNCT
ijassa-998	127	8	dt	dt	PUNCT
ijassa-998	127	9	=	=	PUNCT
ijassa-998	127	10	−γh(t	−γh(t	X
ijassa-998	127	11	)	)	PUNCT
ijassa-998	127	12	+	+	CCONJ
ijassa-998	127	13	u(t	u(t	NOUN
ijassa-998	127	14	)	)	PUNCT
ijassa-998	127	15	0	0	NUM
ijassa-998	127	16	≤	≤	NUM
ijassa-998	127	17	u(t	u(t	NOUN
ijassa-998	127	18	)	)	PUNCT
ijassa-998	127	19	≤	≤	NOUN
ijassa-998	127	20	umax	umax	PROPN
ijassa-998	127	21	,	,	PUNCT
ijassa-998	127	22	t	t	PROPN
ijassa-998	127	23	∈	∈	PROPN
ijassa-998	128	1	[	[	X
ijassa-998	128	2	0	0	NUM
ijassa-998	128	3	,	,	PUNCT
ijassa-998	128	4	t	t	X
ijassa-998	128	5	]	]	PUNCT
ijassa-998	128	6	,	,	PUNCT
ijassa-998	128	7	t	t	PROPN
ijassa-998	128	8	-fixed	-fixe	VERB
ijassa-998	128	9	e(0	e(0	NOUN
ijassa-998	128	10	)	)	PUNCT
ijassa-998	128	11	,	,	PUNCT
ijassa-998	128	12	z(0	z(0	X
ijassa-998	128	13	)	)	PUNCT
ijassa-998	128	14	,	,	PUNCT
ijassa-998	128	15	r(0	r(0	PROPN
ijassa-998	128	16	)	)	PUNCT
ijassa-998	128	17	,	,	PUNCT
ijassa-998	128	18	d(0	d(0	PROPN
ijassa-998	128	19	)	)	PUNCT
ijassa-998	128	20	,	,	PUNCT
ijassa-998	128	21	t	t	PROPN
ijassa-998	128	22	(	(	PUNCT
ijassa-998	128	23	0	0	NUM
ijassa-998	128	24	)	)	PUNCT
ijassa-998	128	25	,	,	PUNCT
ijassa-998	128	26	a(0	a(0	PROPN
ijassa-998	128	27	)	)	PUNCT
ijassa-998	128	28	,	,	PUNCT
ijassa-998	128	29	at(0	at(0	PROPN
ijassa-998	128	30	)	)	PUNCT
ijassa-998	128	31	,	,	PUNCT
ijassa-998	128	32	p	p	X
ijassa-998	128	33	(	(	PUNCT
ijassa-998	128	34	0	0	NUM
ijassa-998	128	35	)	)	PUNCT
ijassa-998	128	36	,	,	PUNCT
ijassa-998	128	37	h(0	h(0	PROPN
ijassa-998	128	38	)	)	PUNCT
ijassa-998	128	39	∈	∈	PROPN
ijassa-998	128	40	r+	r+	NOUN
ijassa-998	128	41	,	,	PUNCT
ijassa-998	128	42	(	(	PUNCT
ijassa-998	128	43	3.4	3.4	NUM
ijassa-998	128	44	)	)	PUNCT
ijassa-998	128	45	and	and	CCONJ
ijassa-998	128	46	the	the	DET
ijassa-998	128	47	state	state	NOUN
ijassa-998	128	48	constraint	constraint	NOUN
ijassa-998	128	49	on	on	ADP
ijassa-998	128	50	the	the	DET
ijassa-998	128	51	amount	amount	NOUN
ijassa-998	128	52	of	of	ADP
ijassa-998	128	53	healthy	healthy	ADJ
ijassa-998	128	54	cells	cell	NOUN
ijassa-998	128	55	g(t	g(t	PROPN
ijassa-998	128	56	)	)	PUNCT
ijassa-998	129	1	=	=	SYM
ijassa-998	129	2	e(t)−	e(t)−	PROPN
ijassa-998	129	3	ec	ec	PROPN
ijassa-998	129	4	≥	≥	PROPN
ijassa-998	129	5	0	0	PUNCT
ijassa-998	129	6	∀t	∀t	PROPN
ijassa-998	129	7	∈	∈	X
ijassa-998	130	1	[	[	X
ijassa-998	130	2	0	0	NUM
ijassa-998	130	3	,	,	PUNCT
ijassa-998	130	4	t	t	X
ijassa-998	130	5	]	]	PUNCT
ijassa-998	130	6	.	.	PUNCT
ijassa-998	131	1	(	(	PUNCT
ijassa-998	131	2	3.5	3.5	NUM
ijassa-998	131	3	)	)	PUNCT
ijassa-998	131	4	the	the	DET
ijassa-998	131	5	last	last	ADJ
ijassa-998	131	6	equation	equation	NOUN
ijassa-998	131	7	in	in	ADP
ijassa-998	131	8	(	(	PUNCT
ijassa-998	131	9	3.4	3.4	NUM
ijassa-998	131	10	)	)	PUNCT
ijassa-998	131	11	describes	describe	VERB
ijassa-998	131	12	the	the	DET
ijassa-998	131	13	pharmacokinetic	pharmacokinetic	NOUN
ijassa-998	131	14	and	and	CCONJ
ijassa-998	131	15	the	the	DET
ijassa-998	131	16	functions	function	NOUN
ijassa-998	131	17	µ(h	µ(h	ADV
ijassa-998	131	18	)	)	PUNCT
ijassa-998	132	1	=	=	SYM
ijassa-998	132	2	µ0	µ0	NOUN
ijassa-998	132	3	(	(	PUNCT
ijassa-998	132	4	1−	1−	NUM
ijassa-998	132	5	kh	kh	X
ijassa-998	132	6	h+	h+	PROPN
ijassa-998	132	7	1	1	NUM
ijassa-998	132	8	)	)	PUNCT
ijassa-998	132	9	and	and	CCONJ
ijassa-998	132	10	µe(h	µe(h	PUNCT
ijassa-998	132	11	)	)	PUNCT
ijassa-998	133	1	=	=	SYM
ijassa-998	133	2	µ0	µ0	NOUN
ijassa-998	133	3	(	(	PUNCT
ijassa-998	133	4	1−	1−	NUM
ijassa-998	133	5	keh	keh	INTJ
ijassa-998	133	6	h+	h+	PROPN
ijassa-998	133	7	1	1	X
ijassa-998	133	8	)	)	PUNCT
ijassa-998	133	9	the	the	DET
ijassa-998	133	10	pharamcodynamic	pharamcodynamic	ADJ
ijassa-998	133	11	of	of	ADP
ijassa-998	133	12	the	the	DET
ijassa-998	133	13	administered	administer	VERB
ijassa-998	133	14	medicine	medicine	NOUN
ijassa-998	133	15	.	.	PUNCT
ijassa-998	134	1	the	the	DET
ijassa-998	134	2	parameters	parameter	NOUN
ijassa-998	134	3	γ	γ	X
ijassa-998	134	4	,	,	PUNCT
ijassa-998	134	5	k	k	PROPN
ijassa-998	134	6	,	,	PUNCT
ijassa-998	134	7	ke	ke	PROPN
ijassa-998	134	8	,	,	PUNCT
ijassa-998	134	9	µ0	µ0	PROPN
ijassa-998	134	10	,	,	PUNCT
ijassa-998	134	11	µ0	µ0	NOUN
ijassa-998	134	12	e	e	NOUN
ijassa-998	134	13	∈	∈	PROPN
ijassa-998	134	14	r+	r+	NOUN
ijassa-998	134	15	,	,	PUNCT
ijassa-998	134	16	where	where	SCONJ
ijassa-998	134	17	γ	γ	PROPN
ijassa-998	134	18	stands	stand	VERB
ijassa-998	134	19	for	for	ADP
ijassa-998	134	20	the	the	DET
ijassa-998	134	21	dissipation	dissipation	NOUN
ijassa-998	134	22	rate	rate	NOUN
ijassa-998	134	23	of	of	ADP
ijassa-998	134	24	the	the	DET
ijassa-998	134	25	administered	administer	VERB
ijassa-998	134	26	drug	drug	NOUN
ijassa-998	134	27	respectively	respectively	ADV
ijassa-998	134	28	,	,	PUNCT
ijassa-998	134	29	k	k	PROPN
ijassa-998	134	30	and	and	CCONJ
ijassa-998	134	31	ke	ke	PROPN
ijassa-998	134	32	describe	describe	VERB
ijassa-998	134	33	the	the	DET
ijassa-998	134	34	effect	effect	NOUN
ijassa-998	134	35	of	of	ADP
ijassa-998	134	36	the	the	DET
ijassa-998	134	37	drug	drug	NOUN
ijassa-998	134	38	on	on	ADP
ijassa-998	134	39	cancer	cancer	NOUN
ijassa-998	134	40	and	and	CCONJ
ijassa-998	134	41	healthy	healthy	ADJ
ijassa-998	134	42	cells	cell	NOUN
ijassa-998	134	43	and	and	CCONJ
ijassa-998	134	44	µ0	µ0	NOUN
ijassa-998	134	45	and	and	CCONJ
ijassa-998	134	46	µ0	µ0	NOUN
ijassa-998	134	47	e	e	NOUN
ijassa-998	134	48	are	be	AUX
ijassa-998	134	49	the	the	DET
ijassa-998	134	50	replication	replication	NOUN
ijassa-998	134	51	rates	rate	NOUN
ijassa-998	134	52	of	of	ADP
ijassa-998	134	53	the	the	DET
ijassa-998	134	54	two	two	NUM
ijassa-998	134	55	cell	cell	NOUN
ijassa-998	134	56	populations	population	NOUN
ijassa-998	134	57	.	.	PUNCT
ijassa-998	135	1	the	the	DET
ijassa-998	135	2	equation	equation	NOUN
ijassa-998	135	3	(	(	PUNCT
ijassa-998	135	4	3.5	3.5	NUM
ijassa-998	135	5	)	)	PUNCT
ijassa-998	135	6	has	have	VERB
ijassa-998	135	7	to	to	PART
ijassa-998	135	8	guarantee	guarantee	VERB
ijassa-998	135	9	that	that	SCONJ
ijassa-998	135	10	the	the	DET
ijassa-998	135	11	amount	amount	NOUN
ijassa-998	135	12	of	of	ADP
ijassa-998	135	13	the	the	DET
ijassa-998	135	14	healthy	healthy	ADJ
ijassa-998	135	15	cells	cell	NOUN
ijassa-998	135	16	does	do	AUX
ijassa-998	135	17	not	not	PART
ijassa-998	135	18	undercut	undercut	VERB
ijassa-998	135	19	a	a	DET
ijassa-998	135	20	given	give	VERB
ijassa-998	135	21	critical	critical	ADJ
ijassa-998	135	22	limit	limit	NOUN
ijassa-998	135	23	ec	ec	PROPN
ijassa-998	135	24	during	during	ADP
ijassa-998	135	25	the	the	DET
ijassa-998	135	26	therapy	therapy	NOUN
ijassa-998	135	27	process	process	NOUN
ijassa-998	135	28	.	.	PUNCT
ijassa-998	136	1	because	because	SCONJ
ijassa-998	136	2	of	of	ADP
ijassa-998	136	3	the	the	DET
ijassa-998	136	4	mathematical	mathematical	ADJ
ijassa-998	136	5	complexity	complexity	NOUN
ijassa-998	136	6	of	of	ADP
ijassa-998	136	7	the	the	DET
ijassa-998	136	8	optimal	optimal	ADJ
ijassa-998	136	9	control	control	NOUN
ijassa-998	136	10	problem	problem	NOUN
ijassa-998	136	11	(	(	PUNCT
ijassa-998	136	12	3.3)-(3.5	3.3)-(3.5	NUM
ijassa-998	136	13	)	)	PUNCT
ijassa-998	136	14	an	an	DET
ijassa-998	136	15	alternative	alternative	ADJ
ijassa-998	136	16	approach	approach	NOUN
ijassa-998	136	17	,	,	PUNCT
ijassa-998	136	18	which	which	PRON
ijassa-998	136	19	will	will	AUX
ijassa-998	136	20	further	far	ADV
ijassa-998	136	21	be	be	AUX
ijassa-998	136	22	called	call	VERB
ijassa-998	136	23	alternative	alternative	ADJ
ijassa-998	136	24	therapy	therapy	NOUN
ijassa-998	136	25	strategy	strategy	NOUN
ijassa-998	136	26	,	,	PUNCT
ijassa-998	136	27	is	be	AUX
ijassa-998	136	28	considered	consider	VERB
ijassa-998	136	29	at	at	ADP
ijassa-998	136	30	first	first	ADV
ijassa-998	136	31	.	.	PUNCT
ijassa-998	137	1	in	in	ADP
ijassa-998	137	2	order	order	NOUN
ijassa-998	137	3	to	to	PART
ijassa-998	137	4	analyze	analyze	VERB
ijassa-998	137	5	whether	whether	SCONJ
ijassa-998	137	6	small	small	ADJ
ijassa-998	137	7	changes	change	NOUN
ijassa-998	137	8	of	of	ADP
ijassa-998	137	9	the	the	DET
ijassa-998	137	10	initial	initial	ADJ
ijassa-998	137	11	conditions	condition	NOUN
ijassa-998	137	12	of	of	ADP
ijassa-998	137	13	the	the	DET
ijassa-998	137	14	considered	consider	VERB
ijassa-998	137	15	system	system	NOUN
ijassa-998	137	16	lead	lead	VERB
ijassa-998	137	17	to	to	ADP
ijassa-998	137	18	a	a	DET
ijassa-998	137	19	different	different	ADJ
ijassa-998	137	20	behaviour	behaviour	NOUN
ijassa-998	137	21	of	of	ADP
ijassa-998	137	22	the	the	DET
ijassa-998	137	23	corresponding	corresponding	ADJ
ijassa-998	137	24	trajectories	trajectory	NOUN
ijassa-998	137	25	its	its	PRON
ijassa-998	137	26	critical	critical	ADJ
ijassa-998	137	27	points	point	NOUN
ijassa-998	137	28	are	be	AUX
ijassa-998	137	29	analyzed	analyze	VERB
ijassa-998	137	30	(	(	PUNCT
ijassa-998	137	31	see	see	VERB
ijassa-998	137	32	a.2	a.2	PUNCT
ijassa-998	137	33	)	)	PUNCT
ijassa-998	137	34	.	.	PUNCT
ijassa-998	138	1	due	due	ADP
ijassa-998	138	2	to	to	ADP
ijassa-998	138	3	the	the	DET
ijassa-998	138	4	practical	practical	ADJ
ijassa-998	138	5	irrelevance	irrelevance	NOUN
ijassa-998	138	6	of	of	ADP
ijassa-998	138	7	the	the	DET
ijassa-998	138	8	trivial	trivial	ADJ
ijassa-998	138	9	critical	critical	ADJ
ijassa-998	138	10	point	point	NOUN
ijassa-998	138	11	(	(	PUNCT
ijassa-998	138	12	ē	ē	ADP
ijassa-998	138	13	,	,	PUNCT
ijassa-998	138	14	z̄	z̄	NOUN
ijassa-998	138	15	,	,	PUNCT
ijassa-998	138	16	h̄	h̄	NOUN
ijassa-998	138	17	)	)	PUNCT
ijassa-998	138	18	=	=	SYM
ijassa-998	138	19	(	(	PUNCT
ijassa-998	138	20	0	0	NUM
ijassa-998	138	21	,	,	PUNCT
ijassa-998	138	22	0	0	NUM
ijassa-998	138	23	)	)	PUNCT
ijassa-998	138	24	only	only	ADV
ijassa-998	138	25	z̄	z̄	PUNCT
ijassa-998	138	26	=	=	PRON
ijassa-998	138	27	(	(	PUNCT
ijassa-998	138	28	1−	1−	NUM
ijassa-998	138	29	δ	δ	PROPN
ijassa-998	138	30	µ(h	µ(h	PROPN
ijassa-998	138	31	)	)	PUNCT
ijassa-998	138	32	)	)	PUNCT
ijassa-998	138	33	η	η	NOUN
ijassa-998	138	34	,	,	PUNCT
ijassa-998	138	35	ē	ē	ADV
ijassa-998	138	36	=	=	NOUN
ijassa-998	138	37	ηe	ηe	ADP
ijassa-998	138	38	−	−	NOUN
ijassa-998	138	39	ε(µ(h)−	ε(µ(h)−	PUNCT
ijassa-998	138	40	δ)η	δ)η	ADJ
ijassa-998	138	41	µe(h)µ(h	µe(h)µ(h	X
ijassa-998	138	42	)	)	PUNCT
ijassa-998	138	43	−	−	NOUN
ijassa-998	138	44	δeηe	δeηe	VERB
ijassa-998	138	45	µe(h	µe(h	PUNCT
ijassa-998	138	46	)	)	PUNCT
ijassa-998	138	47	,	,	PUNCT
ijassa-998	138	48	h̄	h̄	NOUN
ijassa-998	138	49	=	=	SYM
ijassa-998	138	50	u	u	X
ijassa-998	138	51	γ	γ	X
ijassa-998	138	52	(	(	PUNCT
ijassa-998	138	53	3.6	3.6	NUM
ijassa-998	138	54	)	)	PUNCT
ijassa-998	138	55	is	be	AUX
ijassa-998	138	56	taken	take	VERB
ijassa-998	138	57	into	into	ADP
ijassa-998	138	58	account	account	NOUN
ijassa-998	138	59	.	.	PUNCT
ijassa-998	139	1	from	from	ADP
ijassa-998	139	2	the	the	DET
ijassa-998	139	3	dynamical	dynamical	ADJ
ijassa-998	139	4	analysis	analysis	NOUN
ijassa-998	139	5	of	of	ADP
ijassa-998	139	6	the	the	DET
ijassa-998	139	7	considered	consider	VERB
ijassa-998	139	8	system	system	NOUN
ijassa-998	139	9	(	(	PUNCT
ijassa-998	139	10	see	see	VERB
ijassa-998	139	11	a.3	a.3	X
ijassa-998	139	12	)	)	PUNCT
ijassa-998	139	13	it	it	PRON
ijassa-998	139	14	is	be	AUX
ijassa-998	139	15	obvious	obvious	ADJ
ijassa-998	139	16	,	,	PUNCT
ijassa-998	139	17	that	that	SCONJ
ijassa-998	139	18	for	for	ADP
ijassa-998	139	19	realistic	realistic	ADJ
ijassa-998	139	20	parameters	parameter	NOUN
ijassa-998	139	21	of	of	ADP
ijassa-998	139	22	the	the	DET
ijassa-998	139	23	model	model	NOUN
ijassa-998	139	24	the	the	DET
ijassa-998	139	25	critical	critical	ADJ
ijassa-998	139	26	point	point	NOUN
ijassa-998	139	27	(	(	PUNCT
ijassa-998	139	28	3.6	3.6	NUM
ijassa-998	139	29	)	)	PUNCT
ijassa-998	139	30	is	be	AUX
ijassa-998	139	31	a	a	DET
ijassa-998	139	32	stable	stable	ADJ
ijassa-998	139	33	node	node	NOUN
ijassa-998	139	34	.	.	PUNCT
ijassa-998	140	1	copyright	copyright	NOUN
ijassa-998	140	2	c	c	ADP
ijassa-998	140	3	©	©	PROPN
ijassa-998	140	4	2020	2020	NUM
ijassa-998	140	5	assa	assa	NOUN
ijassa-998	140	6	.	.	PUNCT
ijassa-998	141	1	adv	adv	PROPN
ijassa-998	141	2	syst	syst	PROPN
ijassa-998	141	3	sci	sci	PROPN
ijassa-998	141	4	appl	appl	PROPN
ijassa-998	141	5	(	(	PUNCT
ijassa-998	141	6	2020	2020	NUM
ijassa-998	141	7	)	)	PUNCT
ijassa-998	141	8	90	90	NUM
ijassa-998	141	9	m.-c	m.-c	NOUN
ijassa-998	141	10	.	.	PUNCT
ijassa-998	142	1	litzinger	litzinger	NOUN
ijassa-998	142	2	,	,	PUNCT
ijassa-998	142	3	y.	y.	PROPN
ijassa-998	142	4	todorov	todorov	PROPN
ijassa-998	142	5	,	,	PUNCT
ijassa-998	142	6	m.	m.	NOUN
ijassa-998	142	7	föller	föller	PROPN
ijassa-998	142	8	-	-	PUNCT
ijassa-998	142	9	nord	nord	PROPN
ijassa-998	142	10	,	,	PUNCT
ijassa-998	142	11	m.k	m.k	PROPN
ijassa-998	142	12	.	.	PUNCT
ijassa-998	142	13	chaudhary	chaudhary	PROPN
ijassa-998	142	14	,	,	PUNCT
ijassa-998	142	15	a.s	a.s	PROPN
ijassa-998	142	16	.	.	PROPN
ijassa-998	142	17	bratus	bratus	PROPN
ijassa-998	142	18	assuming	assume	VERB
ijassa-998	142	19	now	now	ADV
ijassa-998	142	20	that	that	SCONJ
ijassa-998	142	21	u	u	NOUN
ijassa-998	142	22	is	be	AUX
ijassa-998	142	23	a	a	DET
ijassa-998	142	24	constant	constant	ADJ
ijassa-998	142	25	parameter	parameter	NOUN
ijassa-998	142	26	such	such	ADJ
ijassa-998	142	27	that	that	SCONJ
ijassa-998	142	28	0	0	NUM
ijassa-998	142	29	≤	≤	NUM
ijassa-998	142	30	u	u	NOUN
ijassa-998	142	31	≤	≤	X
ijassa-998	142	32	umax	umax	NOUN
ijassa-998	142	33	we	we	PRON
ijassa-998	142	34	consider	consider	VERB
ijassa-998	142	35	the	the	DET
ijassa-998	142	36	objective	objective	ADJ
ijassa-998	142	37	function	function	NOUN
ijassa-998	142	38	j̃(u	j̃(u	PROPN
ijassa-998	142	39	)	)	PUNCT
ijassa-998	142	40	:	:	PUNCT
ijassa-998	142	41	=	=	SYM
ijassa-998	142	42	j̃(ē	j̃(ē	PROPN
ijassa-998	142	43	,	,	PUNCT
ijassa-998	142	44	z̄	z̄	NOUN
ijassa-998	142	45	)	)	PUNCT
ijassa-998	142	46	=	=	SYM
ijassa-998	142	47	z̄	z̄	PROPN
ijassa-998	143	1	+	+	CCONJ
ijassa-998	143	2	κ(ē	κ(ē	NUM
ijassa-998	143	3	−	−	PROPN
ijassa-998	143	4	ec)2	ec)2	NOUN
ijassa-998	143	5	→	→	SYM
ijassa-998	143	6	min	min	PROPN
ijassa-998	143	7	,	,	PUNCT
ijassa-998	143	8	(	(	PUNCT
ijassa-998	143	9	3.7	3.7	NUM
ijassa-998	143	10	)	)	PUNCT
ijassa-998	143	11	where	where	SCONJ
ijassa-998	143	12	with	with	ADP
ijassa-998	143	13	the	the	DET
ijassa-998	143	14	scale	scale	NOUN
ijassa-998	143	15	of	of	ADP
ijassa-998	143	16	the	the	DET
ijassa-998	143	17	weighting	weighting	NOUN
ijassa-998	143	18	factor	factor	NOUN
ijassa-998	143	19	κ	κ	PROPN
ijassa-998	143	20	∈	∈	PROPN
ijassa-998	143	21	r+	r+	PUNCT
ijassa-998	143	22	the	the	DET
ijassa-998	143	23	state	state	NOUN
ijassa-998	143	24	constraint	constraint	NOUN
ijassa-998	143	25	on	on	ADP
ijassa-998	143	26	the	the	DET
ijassa-998	143	27	amount	amount	NOUN
ijassa-998	143	28	of	of	ADP
ijassa-998	143	29	healthy	healthy	ADJ
ijassa-998	143	30	cells	cell	NOUN
ijassa-998	143	31	is	be	AUX
ijassa-998	143	32	taken	take	VERB
ijassa-998	143	33	into	into	ADP
ijassa-998	143	34	account	account	NOUN
ijassa-998	143	35	.	.	PUNCT
ijassa-998	144	1	it	it	PRON
ijassa-998	144	2	follows	follow	VERB
ijassa-998	144	3	from	from	ADP
ijassa-998	144	4	the	the	DET
ijassa-998	144	5	implicit	implicit	ADJ
ijassa-998	144	6	function	function	NOUN
ijassa-998	144	7	theorem	theorem	VERB
ijassa-998	144	8	that	that	PRON
ijassa-998	144	9	ē	ē	ADV
ijassa-998	144	10	and	and	CCONJ
ijassa-998	144	11	z̄	z̄	AUX
ijassa-998	144	12	can	can	AUX
ijassa-998	144	13	be	be	AUX
ijassa-998	144	14	considered	consider	VERB
ijassa-998	144	15	as	as	ADP
ijassa-998	144	16	functions	function	NOUN
ijassa-998	144	17	of	of	ADP
ijassa-998	144	18	u	u	NOUN
ijassa-998	144	19	and	and	CCONJ
ijassa-998	144	20	consequently	consequently	ADV
ijassa-998	144	21	the	the	DET
ijassa-998	144	22	minimization	minimization	NOUN
ijassa-998	144	23	of	of	ADP
ijassa-998	144	24	the	the	DET
ijassa-998	144	25	functional	functional	ADJ
ijassa-998	144	26	(	(	PUNCT
ijassa-998	144	27	3.7	3.7	NUM
ijassa-998	144	28	)	)	PUNCT
ijassa-998	144	29	can	can	AUX
ijassa-998	144	30	be	be	AUX
ijassa-998	144	31	approached	approach	VERB
ijassa-998	144	32	as	as	ADP
ijassa-998	144	33	a	a	DET
ijassa-998	144	34	mathematical	mathematical	ADJ
ijassa-998	144	35	programming	programming	NOUN
ijassa-998	144	36	problem	problem	NOUN
ijassa-998	144	37	.	.	PUNCT
ijassa-998	145	1	due	due	ADP
ijassa-998	145	2	to	to	ADP
ijassa-998	145	3	the	the	DET
ijassa-998	145	4	theorem	theorem	NOUN
ijassa-998	145	5	of	of	ADP
ijassa-998	145	6	weierstrass	weierstrass	NOUN
ijassa-998	145	7	a	a	DET
ijassa-998	145	8	solution	solution	NOUN
ijassa-998	145	9	of	of	ADP
ijassa-998	145	10	this	this	DET
ijassa-998	145	11	problem	problem	NOUN
ijassa-998	145	12	always	always	ADV
ijassa-998	145	13	exists	exist	VERB
ijassa-998	145	14	.	.	PUNCT
ijassa-998	146	1	assuming	assume	VERB
ijassa-998	146	2	that	that	SCONJ
ijassa-998	146	3	u	u	NOUN
ijassa-998	146	4	=	=	PUNCT
ijassa-998	146	5	ū	ū	X
ijassa-998	146	6	∈	∈	PROPN
ijassa-998	147	1	[	[	X
ijassa-998	147	2	0	0	NUM
ijassa-998	147	3	,	,	PUNCT
ijassa-998	147	4	umax	umax	PROPN
ijassa-998	147	5	]	]	X
ijassa-998	147	6	is	be	AUX
ijassa-998	147	7	the	the	DET
ijassa-998	147	8	value	value	NOUN
ijassa-998	147	9	for	for	ADP
ijassa-998	147	10	which	which	PRON
ijassa-998	147	11	the	the	DET
ijassa-998	147	12	minimum	minimum	NOUN
ijassa-998	147	13	of	of	ADP
ijassa-998	147	14	the	the	DET
ijassa-998	147	15	functional	functional	ADJ
ijassa-998	147	16	(	(	PUNCT
ijassa-998	147	17	3.7	3.7	NUM
ijassa-998	147	18	)	)	PUNCT
ijassa-998	147	19	is	be	AUX
ijassa-998	147	20	achieved	achieve	VERB
ijassa-998	147	21	.	.	PUNCT
ijassa-998	148	1	now	now	ADV
ijassa-998	148	2	consider	consider	VERB
ijassa-998	148	3	the	the	DET
ijassa-998	148	4	function	function	NOUN
ijassa-998	148	5	u(t	u(t	NOUN
ijassa-998	148	6	)	)	PUNCT
ijassa-998	148	7	=	=	PUNCT
ijassa-998	148	8	umax	umax	PROPN
ijassa-998	148	9	,	,	PUNCT
ijassa-998	148	10	0	0	NUM
ijassa-998	148	11	≤	≤	NUM
ijassa-998	148	12	t	t	PROPN
ijassa-998	148	13	≤	≤	NUM
ijassa-998	148	14	t̂.	t̂.	NOUN
ijassa-998	148	15	here	here	ADV
ijassa-998	148	16	umax	umax	ADJ
ijassa-998	148	17	and	and	CCONJ
ijassa-998	148	18	t̂	t̂	NUM
ijassa-998	148	19	are	be	AUX
ijassa-998	148	20	two	two	NUM
ijassa-998	148	21	constants	constant	NOUN
ijassa-998	148	22	such	such	ADJ
ijassa-998	148	23	that	that	SCONJ
ijassa-998	148	24	the	the	DET
ijassa-998	148	25	solution	solution	NOUN
ijassa-998	148	26	of	of	ADP
ijassa-998	148	27	the	the	DET
ijassa-998	148	28	last	last	ADJ
ijassa-998	148	29	equation	equation	NOUN
ijassa-998	148	30	in	in	ADP
ijassa-998	148	31	(	(	PUNCT
ijassa-998	148	32	3.4	3.4	NUM
ijassa-998	148	33	)	)	PUNCT
ijassa-998	148	34	with	with	ADP
ijassa-998	148	35	initial	initial	ADJ
ijassa-998	148	36	condition	condition	NOUN
ijassa-998	148	37	h(0	h(0	PROPN
ijassa-998	148	38	)	)	PUNCT
ijassa-998	148	39	=	=	SYM
ijassa-998	148	40	0	0	PUNCT
ijassa-998	148	41	reaches	reach	VERB
ijassa-998	148	42	the	the	DET
ijassa-998	148	43	value	value	NOUN
ijassa-998	148	44	h	h	NOUN
ijassa-998	148	45	=	=	SYM
ijassa-998	148	46	ū	ū	NOUN
ijassa-998	148	47	γ	γ	NOUN
ijassa-998	148	48	at	at	ADP
ijassa-998	148	49	the	the	DET
ijassa-998	148	50	moment	moment	NOUN
ijassa-998	148	51	t	t	NOUN
ijassa-998	148	52	=	=	PUNCT
ijassa-998	148	53	t̂.	t̂.	NOUN
ijassa-998	148	54	since	since	SCONJ
ijassa-998	148	55	h(t	h(t	NUM
ijassa-998	148	56	)	)	PUNCT
ijassa-998	149	1	=	=	VERB
ijassa-998	149	2	umax	umax	INTJ
ijassa-998	149	3	γh	γh	INTJ
ijassa-998	149	4	(	(	PUNCT
ijassa-998	149	5	1−	1−	NUM
ijassa-998	149	6	e−γt	e−γt	NOUN
ijassa-998	149	7	)	)	PUNCT
ijassa-998	149	8	(	(	PUNCT
ijassa-998	149	9	3.8	3.8	NUM
ijassa-998	149	10	)	)	PUNCT
ijassa-998	149	11	the	the	DET
ijassa-998	149	12	condition	condition	NOUN
ijassa-998	149	13	h(t̂	h(t̂	VERB
ijassa-998	149	14	)	)	PUNCT
ijassa-998	149	15	=	=	SYM
ijassa-998	149	16	ū	ū	NOUN
ijassa-998	149	17	γ	γ	NOUN
ijassa-998	149	18	is	be	AUX
ijassa-998	149	19	fulfilled	fulfil	VERB
ijassa-998	149	20	iff	iff	PROPN
ijassa-998	149	21	t̂	t̂	PUNCT
ijassa-998	149	22	=	=	SYM
ijassa-998	149	23	1	1	NUM
ijassa-998	149	24	γ	γ	X
ijassa-998	149	25	ln	ln	X
ijassa-998	149	26	(	(	PUNCT
ijassa-998	149	27	1−	1−	NUM
ijassa-998	149	28	ū	ū	NOUN
ijassa-998	149	29	umax	umax	ADJ
ijassa-998	149	30	)	)	PUNCT
ijassa-998	149	31	.	.	PUNCT
ijassa-998	150	1	(	(	PUNCT
ijassa-998	150	2	3.9	3.9	NUM
ijassa-998	150	3	)	)	PUNCT
ijassa-998	150	4	the	the	DET
ijassa-998	150	5	last	last	ADJ
ijassa-998	150	6	equality	equality	NOUN
ijassa-998	150	7	provides	provide	VERB
ijassa-998	150	8	the	the	DET
ijassa-998	150	9	required	require	VERB
ijassa-998	150	10	time	time	NOUN
ijassa-998	150	11	of	of	ADP
ijassa-998	150	12	the	the	DET
ijassa-998	150	13	function	function	NOUN
ijassa-998	150	14	h(t	h(t	PROPN
ijassa-998	150	15	)	)	PUNCT
ijassa-998	150	16	to	to	PART
ijassa-998	150	17	reach	reach	VERB
ijassa-998	150	18	the	the	DET
ijassa-998	150	19	value	value	NOUN
ijassa-998	150	20	of	of	ADP
ijassa-998	150	21	ū	ū	NOUN
ijassa-998	150	22	γ	γ	PROPN
ijassa-998	150	23	if	if	SCONJ
ijassa-998	150	24	the	the	DET
ijassa-998	150	25	control	control	NOUN
ijassa-998	150	26	function	function	NOUN
ijassa-998	150	27	u(t	u(t	NOUN
ijassa-998	150	28	)	)	PUNCT
ijassa-998	150	29	=	=	PRON
ijassa-998	151	1	umax	umax	ADJ
ijassa-998	151	2	in	in	ADP
ijassa-998	151	3	the	the	DET
ijassa-998	151	4	time	time	NOUN
ijassa-998	151	5	interval	interval	NOUN
ijassa-998	151	6	0	0	NUM
ijassa-998	151	7	≤	≤	NUM
ijassa-998	151	8	t	t	PROPN
ijassa-998	151	9	≤	≤	NOUN
ijassa-998	151	10	t̂	t̂	NUM
ijassa-998	151	11	,	,	PUNCT
ijassa-998	151	12	which	which	PRON
ijassa-998	151	13	is	be	AUX
ijassa-998	151	14	called	call	VERB
ijassa-998	151	15	intensive	intensive	ADJ
ijassa-998	151	16	therapy	therapy	NOUN
ijassa-998	151	17	time	time	NOUN
ijassa-998	151	18	.	.	PUNCT
ijassa-998	152	1	in	in	ADP
ijassa-998	152	2	the	the	DET
ijassa-998	152	3	remaining	remain	VERB
ijassa-998	152	4	time	time	NOUN
ijassa-998	152	5	interval	interval	NOUN
ijassa-998	152	6	t̂	t̂	ADP
ijassa-998	152	7	<	<	X
ijassa-998	152	8	t	t	PROPN
ijassa-998	152	9	≤	≤	X
ijassa-998	152	10	t	t	PROPN
ijassa-998	152	11	the	the	DET
ijassa-998	152	12	control	control	NOUN
ijassa-998	152	13	function	function	NOUN
ijassa-998	152	14	u(t	u(t	NOUN
ijassa-998	152	15	)	)	PUNCT
ijassa-998	152	16	has	have	VERB
ijassa-998	152	17	to	to	PART
ijassa-998	152	18	keep	keep	VERB
ijassa-998	152	19	the	the	DET
ijassa-998	152	20	value	value	NOUN
ijassa-998	152	21	ū	ū	NOUN
ijassa-998	152	22	γ	γ	NOUN
ijassa-998	152	23	which	which	PRON
ijassa-998	152	24	minimizes	minimize	VERB
ijassa-998	152	25	the	the	DET
ijassa-998	152	26	objective	objective	ADJ
ijassa-998	152	27	function	function	NOUN
ijassa-998	152	28	j̃(u	j̃(u	PROPN
ijassa-998	152	29	)	)	PUNCT
ijassa-998	152	30	.	.	PUNCT
ijassa-998	153	1	this	this	DET
ijassa-998	153	2	therapy	therapy	NOUN
ijassa-998	153	3	interval	interval	NOUN
ijassa-998	153	4	time	time	NOUN
ijassa-998	153	5	is	be	AUX
ijassa-998	153	6	called	call	VERB
ijassa-998	153	7	relaxation	relaxation	NOUN
ijassa-998	153	8	therapy	therapy	NOUN
ijassa-998	153	9	time	time	NOUN
ijassa-998	153	10	.	.	PUNCT
ijassa-998	154	1	the	the	DET
ijassa-998	154	2	determined	determined	ADJ
ijassa-998	154	3	strategy	strategy	NOUN
ijassa-998	154	4	is	be	AUX
ijassa-998	154	5	called	call	VERB
ijassa-998	154	6	alternative	alternative	ADJ
ijassa-998	154	7	therapy	therapy	NOUN
ijassa-998	154	8	strategy	strategy	NOUN
ijassa-998	154	9	and	and	CCONJ
ijassa-998	154	10	can	can	AUX
ijassa-998	154	11	be	be	AUX
ijassa-998	154	12	defined	define	VERB
ijassa-998	154	13	as	as	ADP
ijassa-998	154	14	u(t	u(t	NOUN
ijassa-998	154	15	)	)	PUNCT
ijassa-998	154	16	=	=	SYM
ijassa-998	154	17	umax	umax	PROPN
ijassa-998	154	18	,	,	PUNCT
ijassa-998	154	19	0	0	NUM
ijassa-998	154	20	≤	≤	NUM
ijassa-998	154	21	t	t	PROPN
ijassa-998	154	22	≤	≤	NOUN
ijassa-998	154	23	t̂	t̂	NUM
ijassa-998	154	24	,	,	PUNCT
ijassa-998	154	25	ū	ū	NOUN
ijassa-998	154	26	γ	γ	X
ijassa-998	154	27	,	,	PUNCT
ijassa-998	154	28	t̂	t̂	NUM
ijassa-998	154	29	<	<	X
ijassa-998	154	30	t	t	NOUN
ijassa-998	154	31	≤	≤	NUM
ijassa-998	154	32	t.	t.	NOUN
ijassa-998	154	33	(	(	PUNCT
ijassa-998	154	34	3.10	3.10	NUM
ijassa-998	154	35	)	)	PUNCT
ijassa-998	154	36	according	accord	VERB
ijassa-998	154	37	to	to	ADP
ijassa-998	154	38	the	the	DET
ijassa-998	154	39	considerations	consideration	NOUN
ijassa-998	154	40	above	above	ADP
ijassa-998	154	41	the	the	DET
ijassa-998	154	42	alternative	alternative	ADJ
ijassa-998	154	43	control	control	NOUN
ijassa-998	154	44	strategy	strategy	NOUN
ijassa-998	154	45	consists	consist	VERB
ijassa-998	154	46	out	out	ADP
ijassa-998	154	47	of	of	ADP
ijassa-998	154	48	two	two	NUM
ijassa-998	154	49	stages	stage	NOUN
ijassa-998	154	50	:	:	PUNCT
ijassa-998	154	51	the	the	DET
ijassa-998	154	52	stage	stage	NOUN
ijassa-998	154	53	of	of	ADP
ijassa-998	154	54	the	the	DET
ijassa-998	154	55	intensive	intensive	ADJ
ijassa-998	154	56	therapy	therapy	NOUN
ijassa-998	154	57	and	and	CCONJ
ijassa-998	154	58	the	the	DET
ijassa-998	154	59	stage	stage	NOUN
ijassa-998	154	60	of	of	ADP
ijassa-998	154	61	relaxation	relaxation	NOUN
ijassa-998	154	62	.	.	PUNCT
ijassa-998	155	1	in	in	ADP
ijassa-998	155	2	order	order	NOUN
ijassa-998	155	3	to	to	PART
ijassa-998	155	4	avoid	avoid	VERB
ijassa-998	155	5	disadvantages	disadvantage	NOUN
ijassa-998	155	6	in	in	ADP
ijassa-998	155	7	the	the	DET
ijassa-998	155	8	approach	approach	NOUN
ijassa-998	155	9	considered	consider	VERB
ijassa-998	155	10	above	above	ADV
ijassa-998	155	11	,	,	PUNCT
ijassa-998	155	12	the	the	DET
ijassa-998	155	13	following	follow	VERB
ijassa-998	155	14	modification	modification	NOUN
ijassa-998	155	15	,	,	PUNCT
ijassa-998	155	16	presented	present	VERB
ijassa-998	155	17	in	in	ADP
ijassa-998	155	18	[	[	X
ijassa-998	155	19	22	22	NUM
ijassa-998	155	20	]	]	PUNCT
ijassa-998	155	21	,	,	PUNCT
ijassa-998	155	22	will	will	AUX
ijassa-998	155	23	be	be	AUX
ijassa-998	155	24	used	use	VERB
ijassa-998	155	25	.	.	PUNCT
ijassa-998	156	1	this	this	PRON
ijassa-998	156	2	requires	require	VERB
ijassa-998	156	3	the	the	DET
ijassa-998	156	4	introduction	introduction	NOUN
ijassa-998	156	5	of	of	ADP
ijassa-998	156	6	the	the	DET
ijassa-998	156	7	shifting	shift	VERB
ijassa-998	156	8	variable	variable	NOUN
ijassa-998	156	9	s	s	PART
ijassa-998	156	10	∈	∈	PROPN
ijassa-998	156	11	r+	r+	NOUN
ijassa-998	156	12	in	in	ADP
ijassa-998	156	13	the	the	DET
ijassa-998	156	14	penalty	penalty	NOUN
ijassa-998	156	15	term	term	NOUN
ijassa-998	156	16	of	of	ADP
ijassa-998	156	17	the	the	DET
ijassa-998	156	18	objective	objective	ADJ
ijassa-998	156	19	function	function	NOUN
ijassa-998	156	20	(	(	PUNCT
ijassa-998	156	21	3.7	3.7	NUM
ijassa-998	156	22	)	)	PUNCT
ijassa-998	156	23	j̃(u	j̃(u	PROPN
ijassa-998	156	24	)	)	PUNCT
ijassa-998	156	25	:	:	PUNCT
ijassa-998	157	1	=	=	SYM
ijassa-998	157	2	j̃(ē	j̃(ē	PROPN
ijassa-998	157	3	,	,	PUNCT
ijassa-998	157	4	z̄	z̄	NOUN
ijassa-998	157	5	)	)	PUNCT
ijassa-998	157	6	=	=	SYM
ijassa-998	157	7	z̄	z̄	PROPN
ijassa-998	157	8	+	+	CCONJ
ijassa-998	157	9	κ(ē	κ(ē	NUM
ijassa-998	157	10	−	−	PROPN
ijassa-998	157	11	(	(	PUNCT
ijassa-998	157	12	ec	ec	PROPN
ijassa-998	157	13	+	+	CCONJ
ijassa-998	157	14	s))2	s))2	NOUN
ijassa-998	157	15	→	→	SYM
ijassa-998	157	16	min	min	NOUN
ijassa-998	157	17	.	.	PROPN
ijassa-998	157	18	(	(	PUNCT
ijassa-998	157	19	3.11	3.11	NUM
ijassa-998	157	20	)	)	PUNCT
ijassa-998	157	21	in	in	ADP
ijassa-998	157	22	the	the	DET
ijassa-998	157	23	numerical	numerical	ADJ
ijassa-998	157	24	procedure	procedure	NOUN
ijassa-998	157	25	some	some	DET
ijassa-998	157	26	iterations	iteration	NOUN
ijassa-998	157	27	are	be	AUX
ijassa-998	157	28	usually	usually	ADV
ijassa-998	157	29	necessary	necessary	ADJ
ijassa-998	157	30	to	to	PART
ijassa-998	157	31	obtain	obtain	VERB
ijassa-998	157	32	a	a	DET
ijassa-998	157	33	good	good	ADJ
ijassa-998	157	34	result	result	NOUN
ijassa-998	157	35	and	and	CCONJ
ijassa-998	157	36	the	the	DET
ijassa-998	157	37	new	new	ADJ
ijassa-998	157	38	value	value	NOUN
ijassa-998	157	39	of	of	ADP
ijassa-998	157	40	the	the	DET
ijassa-998	157	41	shifting	shift	VERB
ijassa-998	157	42	variable	variable	NOUN
ijassa-998	157	43	after	after	SCONJ
ijassa-998	157	44	every	every	DET
ijassa-998	157	45	iteration	iteration	NOUN
ijassa-998	157	46	has	have	VERB
ijassa-998	157	47	to	to	PART
ijassa-998	157	48	be	be	AUX
ijassa-998	157	49	calculated	calculate	VERB
ijassa-998	157	50	as	as	SCONJ
ijassa-998	157	51	follows	follow	VERB
ijassa-998	157	52	:	:	PUNCT
ijassa-998	157	53	s(q+1	s(q+1	NUM
ijassa-998	157	54	)	)	PUNCT
ijassa-998	158	1	=	=	SYM
ijassa-998	158	2	s(q	s(q	NOUN
ijassa-998	158	3	)	)	PUNCT
ijassa-998	159	1	+	+	CCONJ
ijassa-998	159	2	max{ec	max{ec	VERB
ijassa-998	159	3	−	−	PRON
ijassa-998	159	4	e(t)|	e(t)|	ADJ
ijassa-998	159	5	e(t	e(t	NOUN
ijassa-998	159	6	)	)	PUNCT
ijassa-998	159	7	<	<	X
ijassa-998	159	8	ec	ec	PROPN
ijassa-998	159	9	,	,	PUNCT
ijassa-998	159	10	t	t	PROPN
ijassa-998	159	11	∈	∈	PROPN
ijassa-998	159	12	(	(	PUNCT
ijassa-998	159	13	0	0	NUM
ijassa-998	159	14	,	,	PUNCT
ijassa-998	159	15	t	t	NOUN
ijassa-998	159	16	)	)	PUNCT
ijassa-998	159	17	}	}	PUNCT
ijassa-998	159	18	,	,	PUNCT
ijassa-998	159	19	where	where	SCONJ
ijassa-998	159	20	q	q	NOUN
ijassa-998	159	21	is	be	AUX
ijassa-998	159	22	the	the	DET
ijassa-998	159	23	number	number	NOUN
ijassa-998	159	24	of	of	ADP
ijassa-998	159	25	the	the	DET
ijassa-998	159	26	last	last	ADJ
ijassa-998	159	27	iteration	iteration	NOUN
ijassa-998	159	28	.	.	PUNCT
ijassa-998	160	1	if	if	SCONJ
ijassa-998	160	2	the	the	DET
ijassa-998	160	3	maximal	maximal	ADJ
ijassa-998	160	4	number	number	NOUN
ijassa-998	160	5	of	of	ADP
ijassa-998	160	6	iteration	iteration	NOUN
ijassa-998	160	7	qmax	qmax	NOUN
ijassa-998	160	8	or	or	CCONJ
ijassa-998	160	9	the	the	DET
ijassa-998	160	10	desired	desire	VERB
ijassa-998	160	11	accuracy	accuracy	NOUN
ijassa-998	160	12	θ	θ	PROPN
ijassa-998	160	13	≥	≥	NUM
ijassa-998	160	14	|s(q	|s(q	NOUN
ijassa-998	160	15	)	)	PUNCT
ijassa-998	160	16	−	−	PROPN
ijassa-998	160	17	s(q−1)|	s(q−1)|	NOUN
ijassa-998	160	18	is	be	AUX
ijassa-998	160	19	reached	reach	VERB
ijassa-998	160	20	the	the	DET
ijassa-998	160	21	procedure	procedure	NOUN
ijassa-998	160	22	has	have	VERB
ijassa-998	160	23	to	to	PART
ijassa-998	160	24	be	be	AUX
ijassa-998	160	25	terminated	terminate	VERB
ijassa-998	160	26	.	.	PUNCT
ijassa-998	161	1	the	the	DET
ijassa-998	161	2	following	follow	VERB
ijassa-998	161	3	numerical	numerical	ADJ
ijassa-998	161	4	results	result	NOUN
ijassa-998	161	5	illustrate	illustrate	VERB
ijassa-998	161	6	the	the	DET
ijassa-998	161	7	time	time	NOUN
ijassa-998	161	8	response	response	NOUN
ijassa-998	161	9	of	of	ADP
ijassa-998	161	10	healthy	healthy	ADJ
ijassa-998	161	11	and	and	CCONJ
ijassa-998	161	12	cancer	cancer	NOUN
ijassa-998	161	13	cells	cell	NOUN
ijassa-998	161	14	as	as	ADV
ijassa-998	161	15	well	well	ADV
ijassa-998	161	16	as	as	ADP
ijassa-998	161	17	the	the	DET
ijassa-998	161	18	psa	psa	NOUN
ijassa-998	161	19	-	-	PUNCT
ijassa-998	161	20	level	level	NOUN
ijassa-998	161	21	and	and	CCONJ
ijassa-998	161	22	the	the	DET
ijassa-998	161	23	control	control	NOUN
ijassa-998	161	24	function	function	NOUN
ijassa-998	161	25	using	use	VERB
ijassa-998	161	26	the	the	DET
ijassa-998	161	27	alternative	alternative	ADJ
ijassa-998	161	28	therapy	therapy	NOUN
ijassa-998	161	29	strategy	strategy	NOUN
ijassa-998	161	30	.	.	PUNCT
ijassa-998	162	1	copyright	copyright	NOUN
ijassa-998	162	2	c	c	ADP
ijassa-998	162	3	©	©	PROPN
ijassa-998	162	4	2020	2020	NUM
ijassa-998	162	5	assa	assa	NOUN
ijassa-998	162	6	.	.	PUNCT
ijassa-998	163	1	adv	adv	PROPN
ijassa-998	163	2	syst	syst	PROPN
ijassa-998	163	3	sci	sci	PROPN
ijassa-998	163	4	appl	appl	PROPN
ijassa-998	163	5	(	(	PUNCT
ijassa-998	163	6	2020	2020	NUM
ijassa-998	163	7	)	)	PUNCT
ijassa-998	163	8	on	on	ADP
ijassa-998	163	9	optimal	optimal	ADJ
ijassa-998	163	10	therapy	therapy	NOUN
ijassa-998	163	11	protocols	protocol	NOUN
ijassa-998	163	12	in	in	ADP
ijassa-998	163	13	the	the	DET
ijassa-998	163	14	math	math	NOUN
ijassa-998	163	15	.	.	PUNCT
ijassa-998	164	1	model	model	NOUN
ijassa-998	164	2	of	of	ADP
ijassa-998	164	3	prostate	prostate	NOUN
ijassa-998	164	4	cancer	cancer	NOUN
ijassa-998	164	5	progression	progression	NOUN
ijassa-998	164	6	91	91	NUM
ijassa-998	164	7	0	0	NUM
ijassa-998	164	8	50	50	NUM
ijassa-998	164	9	100	100	NUM
ijassa-998	164	10	150	150	NUM
ijassa-998	164	11	non	non	ADJ
ijassa-998	164	12	-	-	ADJ
ijassa-998	164	13	dimensional	dimensional	ADJ
ijassa-998	164	14	time	time	NOUN
ijassa-998	164	15	44	44	NUM
ijassa-998	164	16	46	46	NUM
ijassa-998	164	17	48	48	NUM
ijassa-998	164	18	50	50	NUM
ijassa-998	164	19	52	52	NUM
ijassa-998	164	20	54	54	NUM
ijassa-998	164	21	56	56	NUM
ijassa-998	164	22	58	58	NUM
ijassa-998	164	23	fig	fig	NOUN
ijassa-998	164	24	.	.	PUNCT
ijassa-998	165	1	3.6	3.6	NUM
ijassa-998	165	2	.	.	PUNCT
ijassa-998	165	3	time	time	NOUN
ijassa-998	165	4	response	response	NOUN
ijassa-998	165	5	of	of	ADP
ijassa-998	165	6	healthy	healthy	ADJ
ijassa-998	165	7	cells	cell	NOUN
ijassa-998	165	8	e(t	e(t	NOUN
ijassa-998	165	9	)	)	PUNCT
ijassa-998	166	1	using	use	VERB
ijassa-998	166	2	the	the	DET
ijassa-998	166	3	alternative	alternative	ADJ
ijassa-998	166	4	therapy	therapy	NOUN
ijassa-998	166	5	strategy	strategy	NOUN
ijassa-998	166	6	0	0	NUM
ijassa-998	166	7	50	50	NUM
ijassa-998	166	8	100	100	NUM
ijassa-998	166	9	150	150	NUM
ijassa-998	166	10	non	non	ADJ
ijassa-998	166	11	-	-	ADJ
ijassa-998	166	12	dimensional	dimensional	ADJ
ijassa-998	166	13	time	time	NOUN
ijassa-998	166	14	115	115	NUM
ijassa-998	166	15	120	120	NUM
ijassa-998	166	16	125	125	NUM
ijassa-998	166	17	130	130	NUM
ijassa-998	166	18	135	135	NUM
ijassa-998	166	19	140	140	NUM
ijassa-998	166	20	145	145	NUM
ijassa-998	166	21	150	150	NUM
ijassa-998	166	22	fig	fig	NOUN
ijassa-998	166	23	.	.	PUNCT
ijassa-998	167	1	3.7	3.7	NUM
ijassa-998	167	2	.	.	PUNCT
ijassa-998	167	3	time	time	NOUN
ijassa-998	167	4	response	response	NOUN
ijassa-998	167	5	of	of	ADP
ijassa-998	167	6	cancer	cancer	NOUN
ijassa-998	167	7	cells	cell	NOUN
ijassa-998	167	8	z(t	z(t	NOUN
ijassa-998	167	9	)	)	PUNCT
ijassa-998	167	10	using	use	VERB
ijassa-998	167	11	the	the	DET
ijassa-998	167	12	alternative	alternative	ADJ
ijassa-998	167	13	therapy	therapy	NOUN
ijassa-998	167	14	strategy	strategy	NOUN
ijassa-998	167	15	cancer	cancer	NOUN
ijassa-998	167	16	and	and	CCONJ
ijassa-998	167	17	healthy	healthy	ADJ
ijassa-998	167	18	cells	cell	NOUN
ijassa-998	167	19	decrease	decrease	NOUN
ijassa-998	167	20	(	(	PUNCT
ijassa-998	167	21	fig	fig	NOUN
ijassa-998	167	22	.	.	PUNCT
ijassa-998	168	1	3.6	3.6	NUM
ijassa-998	168	2	)	)	PUNCT
ijassa-998	168	3	,	,	PUNCT
ijassa-998	168	4	(	(	PUNCT
ijassa-998	168	5	fig	fig	NOUN
ijassa-998	168	6	.	.	PUNCT
ijassa-998	169	1	3.7	3.7	NUM
ijassa-998	169	2	)	)	PUNCT
ijassa-998	169	3	.	.	PUNCT
ijassa-998	170	1	healthy	healthy	ADJ
ijassa-998	170	2	cells	cell	NOUN
ijassa-998	170	3	reach	reach	VERB
ijassa-998	170	4	the	the	DET
ijassa-998	170	5	constraint	constraint	NOUN
ijassa-998	170	6	boundary	boundary	NOUN
ijassa-998	170	7	without	without	ADP
ijassa-998	170	8	violating	violate	VERB
ijassa-998	170	9	it	it	PRON
ijassa-998	170	10	.	.	PUNCT
ijassa-998	171	1	copyright	copyright	NOUN
ijassa-998	171	2	c	c	ADP
ijassa-998	171	3	©	©	PROPN
ijassa-998	171	4	2020	2020	NUM
ijassa-998	171	5	assa	assa	NOUN
ijassa-998	171	6	.	.	PUNCT
ijassa-998	172	1	adv	adv	PROPN
ijassa-998	172	2	syst	syst	PROPN
ijassa-998	172	3	sci	sci	PROPN
ijassa-998	172	4	appl	appl	PROPN
ijassa-998	172	5	(	(	PUNCT
ijassa-998	172	6	2020	2020	NUM
ijassa-998	172	7	)	)	PUNCT
ijassa-998	172	8	92	92	NUM
ijassa-998	172	9	m.-c	m.-c	NOUN
ijassa-998	172	10	.	.	PUNCT
ijassa-998	173	1	litzinger	litzinger	NOUN
ijassa-998	173	2	,	,	PUNCT
ijassa-998	173	3	y.	y.	PROPN
ijassa-998	173	4	todorov	todorov	PROPN
ijassa-998	173	5	,	,	PUNCT
ijassa-998	173	6	m.	m.	NOUN
ijassa-998	173	7	föller	föller	PROPN
ijassa-998	173	8	-	-	PUNCT
ijassa-998	173	9	nord	nord	PROPN
ijassa-998	173	10	,	,	PUNCT
ijassa-998	173	11	m.k	m.k	PROPN
ijassa-998	173	12	.	.	PUNCT
ijassa-998	173	13	chaudhary	chaudhary	PROPN
ijassa-998	173	14	,	,	PUNCT
ijassa-998	173	15	a.s	a.s	PROPN
ijassa-998	173	16	.	.	PROPN
ijassa-998	173	17	bratus	bratus	PROPN
ijassa-998	173	18	0	0	NUM
ijassa-998	173	19	50	50	NUM
ijassa-998	173	20	100	100	NUM
ijassa-998	173	21	150	150	NUM
ijassa-998	173	22	non	non	ADJ
ijassa-998	173	23	-	-	ADJ
ijassa-998	173	24	dimensional	dimensional	ADJ
ijassa-998	173	25	time	time	NOUN
ijassa-998	173	26	0	0	NUM
ijassa-998	173	27	0.5	0.5	NUM
ijassa-998	173	28	1	1	NUM
ijassa-998	173	29	1.5	1.5	NUM
ijassa-998	173	30	2	2	NUM
ijassa-998	173	31	2.5	2.5	NUM
ijassa-998	173	32	3	3	NUM
ijassa-998	173	33	3.5	3.5	NUM
ijassa-998	173	34	4	4	NUM
ijassa-998	173	35	4.5	4.5	NUM
ijassa-998	173	36	5	5	NUM
ijassa-998	173	37	fig	fig	NOUN
ijassa-998	173	38	.	.	PUNCT
ijassa-998	174	1	3.8	3.8	NUM
ijassa-998	174	2	.	.	PUNCT
ijassa-998	174	3	amount	amount	NOUN
ijassa-998	174	4	of	of	ADP
ijassa-998	174	5	the	the	DET
ijassa-998	174	6	administered	administer	VERB
ijassa-998	174	7	drug	drug	NOUN
ijassa-998	174	8	u(t	u(t	NOUN
ijassa-998	174	9	)	)	PUNCT
ijassa-998	174	10	using	use	VERB
ijassa-998	174	11	the	the	DET
ijassa-998	174	12	alternative	alternative	ADJ
ijassa-998	174	13	therapy	therapy	NOUN
ijassa-998	174	14	strategy	strategy	NOUN
ijassa-998	174	15	0	0	NUM
ijassa-998	174	16	50	50	NUM
ijassa-998	174	17	100	100	NUM
ijassa-998	174	18	150	150	NUM
ijassa-998	174	19	non	non	ADJ
ijassa-998	174	20	-	-	ADJ
ijassa-998	174	21	dimensional	dimensional	ADJ
ijassa-998	174	22	time	time	NOUN
ijassa-998	174	23	0	0	NUM
ijassa-998	174	24	1	1	NUM
ijassa-998	174	25	2	2	NUM
ijassa-998	174	26	3	3	NUM
ijassa-998	174	27	4	4	NUM
ijassa-998	174	28	5	5	NUM
ijassa-998	174	29	6	6	NUM
ijassa-998	174	30	7	7	NUM
ijassa-998	174	31	8	8	NUM
ijassa-998	174	32	9	9	NUM
ijassa-998	174	33	10	10	NUM
ijassa-998	174	34	fig	fig	NOUN
ijassa-998	174	35	.	.	PUNCT
ijassa-998	175	1	3.9	3.9	NUM
ijassa-998	175	2	.	.	PUNCT
ijassa-998	175	3	time	time	NOUN
ijassa-998	175	4	response	response	NOUN
ijassa-998	175	5	of	of	ADP
ijassa-998	175	6	the	the	DET
ijassa-998	175	7	psa	psa	NOUN
ijassa-998	175	8	function	function	PROPN
ijassa-998	175	9	p	p	PROPN
ijassa-998	175	10	(	(	PUNCT
ijassa-998	175	11	t	t	NOUN
ijassa-998	175	12	)	)	PUNCT
ijassa-998	175	13	using	use	VERB
ijassa-998	175	14	the	the	DET
ijassa-998	175	15	alternative	alternative	ADJ
ijassa-998	175	16	therapy	therapy	NOUN
ijassa-998	175	17	strategy	strategy	NOUN
ijassa-998	175	18	the	the	DET
ijassa-998	175	19	maximal	maximal	ADJ
ijassa-998	175	20	dose	dose	NOUN
ijassa-998	175	21	of	of	ADP
ijassa-998	175	22	therapy	therapy	NOUN
ijassa-998	175	23	is	be	AUX
ijassa-998	175	24	used	use	VERB
ijassa-998	175	25	for	for	ADP
ijassa-998	175	26	a	a	DET
ijassa-998	175	27	short	short	ADJ
ijassa-998	175	28	amount	amount	NOUN
ijassa-998	175	29	of	of	ADP
ijassa-998	175	30	time	time	NOUN
ijassa-998	175	31	and	and	CCONJ
ijassa-998	175	32	then	then	ADV
ijassa-998	175	33	a	a	DET
ijassa-998	175	34	constant	constant	ADJ
ijassa-998	175	35	amount	amount	NOUN
ijassa-998	175	36	is	be	AUX
ijassa-998	175	37	administered	administer	VERB
ijassa-998	175	38	(	(	PUNCT
ijassa-998	175	39	fig	fig	NOUN
ijassa-998	175	40	.	.	PUNCT
ijassa-998	176	1	3.8	3.8	NUM
ijassa-998	176	2	)	)	PUNCT
ijassa-998	176	3	.	.	PUNCT
ijassa-998	177	1	due	due	ADP
ijassa-998	177	2	to	to	ADP
ijassa-998	177	3	the	the	DET
ijassa-998	177	4	reduction	reduction	NOUN
ijassa-998	177	5	of	of	ADP
ijassa-998	177	6	cancer	cancer	NOUN
ijassa-998	177	7	cells	cell	NOUN
ijassa-998	177	8	less	less	ADJ
ijassa-998	177	9	psa	psa	NOUN
ijassa-998	177	10	is	be	AUX
ijassa-998	177	11	produced	produce	VERB
ijassa-998	177	12	in	in	ADP
ijassa-998	177	13	the	the	DET
ijassa-998	177	14	tissue	tissue	NOUN
ijassa-998	177	15	and	and	CCONJ
ijassa-998	177	16	can	can	AUX
ijassa-998	177	17	consequently	consequently	ADV
ijassa-998	177	18	be	be	AUX
ijassa-998	177	19	found	find	VERB
ijassa-998	177	20	in	in	ADP
ijassa-998	177	21	the	the	DET
ijassa-998	177	22	blood	blood	NOUN
ijassa-998	177	23	serum	serum	NOUN
ijassa-998	177	24	(	(	PUNCT
ijassa-998	177	25	fig	fig	NOUN
ijassa-998	177	26	.	.	PUNCT
ijassa-998	178	1	3.9	3.9	NUM
ijassa-998	178	2	)	)	PUNCT
ijassa-998	178	3	.	.	PUNCT
ijassa-998	179	1	copyright	copyright	NOUN
ijassa-998	179	2	c	c	ADP
ijassa-998	179	3	©	©	PROPN
ijassa-998	179	4	2020	2020	NUM
ijassa-998	179	5	assa	assa	NOUN
ijassa-998	179	6	.	.	PUNCT
ijassa-998	180	1	adv	adv	PROPN
ijassa-998	180	2	syst	syst	PROPN
ijassa-998	180	3	sci	sci	PROPN
ijassa-998	180	4	appl	appl	PROPN
ijassa-998	180	5	(	(	PUNCT
ijassa-998	180	6	2020	2020	NUM
ijassa-998	180	7	)	)	PUNCT
ijassa-998	180	8	on	on	ADP
ijassa-998	180	9	optimal	optimal	ADJ
ijassa-998	180	10	therapy	therapy	NOUN
ijassa-998	180	11	protocols	protocol	NOUN
ijassa-998	180	12	in	in	ADP
ijassa-998	180	13	the	the	DET
ijassa-998	180	14	math	math	NOUN
ijassa-998	180	15	.	.	PUNCT
ijassa-998	181	1	model	model	NOUN
ijassa-998	181	2	of	of	ADP
ijassa-998	181	3	prostate	prostate	NOUN
ijassa-998	181	4	cancer	cancer	NOUN
ijassa-998	181	5	progression	progression	NOUN
ijassa-998	181	6	93	93	NUM
ijassa-998	181	7	4	4	NUM
ijassa-998	181	8	.	.	PUNCT
ijassa-998	181	9	suboptimal	suboptimal	ADJ
ijassa-998	181	10	therapy	therapy	NOUN
ijassa-998	181	11	strategy	strategy	NOUN
ijassa-998	181	12	in	in	ADP
ijassa-998	181	13	this	this	DET
ijassa-998	181	14	section	section	NOUN
ijassa-998	181	15	a	a	DET
ijassa-998	181	16	suboptimal	suboptimal	ADJ
ijassa-998	181	17	therapy	therapy	NOUN
ijassa-998	181	18	strategy	strategy	NOUN
ijassa-998	181	19	for	for	ADP
ijassa-998	181	20	the	the	DET
ijassa-998	181	21	problem	problem	NOUN
ijassa-998	181	22	(	(	PUNCT
ijassa-998	181	23	3.3)-(3.5	3.3)-(3.5	NUM
ijassa-998	181	24	)	)	PUNCT
ijassa-998	181	25	is	be	AUX
ijassa-998	181	26	introduced	introduce	VERB
ijassa-998	181	27	.	.	PUNCT
ijassa-998	182	1	in	in	ADP
ijassa-998	182	2	order	order	NOUN
ijassa-998	182	3	to	to	PART
ijassa-998	182	4	minimize	minimize	VERB
ijassa-998	182	5	the	the	DET
ijassa-998	182	6	objective	objective	ADJ
ijassa-998	182	7	function	function	NOUN
ijassa-998	182	8	(	(	PUNCT
ijassa-998	182	9	3.3	3.3	NUM
ijassa-998	182	10	)	)	PUNCT
ijassa-998	182	11	it	it	PRON
ijassa-998	182	12	is	be	AUX
ijassa-998	182	13	natural	natural	ADJ
ijassa-998	182	14	to	to	PART
ijassa-998	182	15	apply	apply	VERB
ijassa-998	182	16	the	the	DET
ijassa-998	182	17	maximal	maximal	ADJ
ijassa-998	182	18	admissible	admissible	ADJ
ijassa-998	182	19	amount	amount	NOUN
ijassa-998	182	20	of	of	ADP
ijassa-998	182	21	the	the	DET
ijassa-998	182	22	drug	drug	NOUN
ijassa-998	182	23	so	so	ADV
ijassa-998	182	24	long	long	ADV
ijassa-998	182	25	as	as	ADP
ijassa-998	182	26	possible	possible	ADJ
ijassa-998	182	27	.	.	PUNCT
ijassa-998	183	1	however	however	ADV
ijassa-998	183	2	,	,	PUNCT
ijassa-998	183	3	it	it	PRON
ijassa-998	183	4	has	have	VERB
ijassa-998	183	5	to	to	PART
ijassa-998	183	6	be	be	AUX
ijassa-998	183	7	guaranteed	guarantee	VERB
ijassa-998	183	8	that	that	SCONJ
ijassa-998	183	9	the	the	DET
ijassa-998	183	10	amount	amount	NOUN
ijassa-998	183	11	of	of	ADP
ijassa-998	183	12	healthy	healthy	ADJ
ijassa-998	183	13	cells	cell	NOUN
ijassa-998	183	14	does	do	AUX
ijassa-998	183	15	not	not	PART
ijassa-998	183	16	violate	violate	VERB
ijassa-998	183	17	the	the	DET
ijassa-998	183	18	constraint	constraint	NOUN
ijassa-998	183	19	(	(	PUNCT
ijassa-998	183	20	3.5	3.5	NUM
ijassa-998	183	21	)	)	PUNCT
ijassa-998	183	22	.	.	PUNCT
ijassa-998	184	1	i.e.	i.e.	X
ijassa-998	184	2	that	that	SCONJ
ijassa-998	184	3	the	the	DET
ijassa-998	184	4	time	time	NOUN
ijassa-998	184	5	derivation	derivation	NOUN
ijassa-998	184	6	ė	ė	ADJ
ijassa-998	184	7	on	on	ADP
ijassa-998	184	8	the	the	DET
ijassa-998	184	9	constraint	constraint	NOUN
ijassa-998	184	10	boundary	boundary	NOUN
ijassa-998	184	11	has	have	VERB
ijassa-998	184	12	to	to	PART
ijassa-998	184	13	be	be	AUX
ijassa-998	184	14	non	non	X
ijassa-998	184	15	negative	negative	ADJ
ijassa-998	184	16	.	.	PUNCT
ijassa-998	185	1	from	from	ADP
ijassa-998	185	2	ė(tj	ė(tj	NOUN
ijassa-998	185	3	)	)	PUNCT
ijassa-998	185	4	≥	≥	X
ijassa-998	185	5	0	0	NUM
ijassa-998	185	6	follows	follow	VERB
ijassa-998	185	7	µe(h)ec	µe(h)ec	PROPN
ijassa-998	185	8	(	(	PUNCT
ijassa-998	185	9	1−	1−	NUM
ijassa-998	185	10	ec	ec	PROPN
ijassa-998	185	11	ηe	ηe	ADP
ijassa-998	185	12	)	)	PUNCT
ijassa-998	185	13	−	−	PROPN
ijassa-998	185	14	εecz(tj	εecz(tj	PROPN
ijassa-998	185	15	)	)	PUNCT
ijassa-998	185	16	ηe	ηe	ADP
ijassa-998	185	17	−	−	PROPN
ijassa-998	185	18	δeec	δeec	ADJ
ijassa-998	185	19	≥	≥	NOUN
ijassa-998	185	20	0	0	NUM
ijassa-998	185	21	⇒	⇒	PROPN
ijassa-998	185	22	µ0	µ0	NOUN
ijassa-998	185	23	e	e	PROPN
ijassa-998	185	24	(	(	PUNCT
ijassa-998	185	25	1−	1−	NUM
ijassa-998	185	26	keh(tj	keh(tj	NOUN
ijassa-998	185	27	)	)	PUNCT
ijassa-998	185	28	h(tj	h(tj	PROPN
ijassa-998	185	29	)	)	PUNCT
ijassa-998	186	1	+	+	CCONJ
ijassa-998	186	2	1	1	X
ijassa-998	186	3	)	)	PUNCT
ijassa-998	186	4	≥	≥	NOUN
ijassa-998	186	5	εz(tj	εz(tj	PROPN
ijassa-998	186	6	)	)	PUNCT
ijassa-998	186	7	+	+	CCONJ
ijassa-998	186	8	δeηe	δeηe	VERB
ijassa-998	186	9	ηe	ηe	ADP
ijassa-998	186	10	−	−	PROPN
ijassa-998	186	11	ec	ec	PROPN
ijassa-998	186	12	⇒	⇒	PROPN
ijassa-998	186	13	keh(tj	keh(tj	VERB
ijassa-998	186	14	)	)	PUNCT
ijassa-998	186	15	≤	≤	NOUN
ijassa-998	186	16	(	(	PUNCT
ijassa-998	186	17	1−	1−	NUM
ijassa-998	186	18	εz(tj	εz(tj	ADJ
ijassa-998	186	19	)	)	PUNCT
ijassa-998	186	20	+	+	CCONJ
ijassa-998	186	21	δeηe	δeηe	X
ijassa-998	186	22	(	(	PUNCT
ijassa-998	186	23	ηe	ηe	ADP
ijassa-998	186	24	−	−	PROPN
ijassa-998	186	25	ec)µ0	ec)µ0	PROPN
ijassa-998	186	26	e	e	PROPN
ijassa-998	186	27	)	)	PUNCT
ijassa-998	186	28	(	(	PUNCT
ijassa-998	186	29	h(tj	h(tj	NOUN
ijassa-998	186	30	)	)	PUNCT
ijassa-998	186	31	+	+	CCONJ
ijassa-998	186	32	1	1	X
ijassa-998	186	33	)	)	PUNCT
ijassa-998	186	34	(	(	PUNCT
ijassa-998	186	35	4.12	4.12	NUM
ijassa-998	186	36	)	)	PUNCT
ijassa-998	186	37	⇒	⇒	NOUN
ijassa-998	186	38	h(tj	h(tj	NUM
ijassa-998	186	39	)	)	PUNCT
ijassa-998	186	40	(	(	PUNCT
ijassa-998	186	41	ke	ke	NOUN
ijassa-998	186	42	−	−	PROPN
ijassa-998	186	43	(	(	PUNCT
ijassa-998	186	44	1−	1−	NUM
ijassa-998	186	45	εz(tj	εz(tj	PROPN
ijassa-998	186	46	)	)	PUNCT
ijassa-998	187	1	+	+	CCONJ
ijassa-998	187	2	δeηe	δeηe	X
ijassa-998	187	3	(	(	PUNCT
ijassa-998	187	4	ηe	ηe	ADP
ijassa-998	187	5	−	−	PROPN
ijassa-998	187	6	ec)µ0	ec)µ0	PROPN
ijassa-998	187	7	e	e	PROPN
ijassa-998	187	8	)	)	PUNCT
ijassa-998	187	9	)	)	PUNCT
ijassa-998	187	10	≤	≤	NOUN
ijassa-998	187	11	(	(	PUNCT
ijassa-998	187	12	1−	1−	NUM
ijassa-998	187	13	εz(tj	εz(tj	ADJ
ijassa-998	187	14	)	)	PUNCT
ijassa-998	188	1	+	+	CCONJ
ijassa-998	188	2	δeηe	δeηe	X
ijassa-998	188	3	(	(	PUNCT
ijassa-998	188	4	ηe	ηe	ADP
ijassa-998	188	5	−	−	PROPN
ijassa-998	188	6	ec)µ0	ec)µ0	PROPN
ijassa-998	188	7	e	e	PROPN
ijassa-998	188	8	)	)	PUNCT
ijassa-998	188	9	⇒	⇒	PROPN
ijassa-998	188	10	h(tj	h(tj	NUM
ijassa-998	188	11	)	)	PUNCT
ijassa-998	188	12	≤	≤	NOUN
ijassa-998	188	13	(	(	PUNCT
ijassa-998	188	14	1−	1−	NUM
ijassa-998	188	15	εz(tj	εz(tj	ADJ
ijassa-998	188	16	)	)	PUNCT
ijassa-998	189	1	+	+	CCONJ
ijassa-998	189	2	δeηe	δeηe	X
ijassa-998	189	3	(	(	PUNCT
ijassa-998	189	4	ηe	ηe	ADP
ijassa-998	189	5	−	−	PROPN
ijassa-998	189	6	ec)µ0	ec)µ0	PROPN
ijassa-998	189	7	e	e	PROPN
ijassa-998	189	8	)	)	PUNCT
ijassa-998	189	9	ke	ke	NOUN
ijassa-998	189	10	−	−	PROPN
ijassa-998	190	1	(	(	PUNCT
ijassa-998	190	2	1−	1−	NUM
ijassa-998	190	3	εz(tj	εz(tj	PROPN
ijassa-998	190	4	)	)	PUNCT
ijassa-998	191	1	+	+	CCONJ
ijassa-998	191	2	δeηe	δeηe	X
ijassa-998	191	3	(	(	PUNCT
ijassa-998	191	4	ηe	ηe	ADP
ijassa-998	191	5	−	−	PROPN
ijassa-998	191	6	ec)µ0	ec)µ0	PROPN
ijassa-998	191	7	e	e	PROPN
ijassa-998	191	8	)	)	PUNCT
ijassa-998	191	9	,	,	PUNCT
ijassa-998	191	10	where	where	SCONJ
ijassa-998	191	11	tj	tj	X
ijassa-998	191	12	:	:	PUNCT
ijassa-998	191	13	=	=	X
ijassa-998	191	14	{	{	PUNCT
ijassa-998	191	15	t	t	NOUN
ijassa-998	191	16	∈	∈	PROPN
ijassa-998	191	17	(	(	PUNCT
ijassa-998	191	18	0	0	NUM
ijassa-998	191	19	,	,	PUNCT
ijassa-998	191	20	t	t	NOUN
ijassa-998	191	21	)	)	PUNCT
ijassa-998	191	22	|	|	ADV
ijassa-998	191	23	e(t	e(t	NOUN
ijassa-998	191	24	)	)	PUNCT
ijassa-998	191	25	=	=	SYM
ijassa-998	191	26	ec	ec	PROPN
ijassa-998	191	27	}	}	PUNCT
ijassa-998	191	28	.	.	PUNCT
ijassa-998	192	1	due	due	ADP
ijassa-998	192	2	to	to	ADP
ijassa-998	192	3	the	the	DET
ijassa-998	192	4	continuity	continuity	NOUN
ijassa-998	192	5	of	of	ADP
ijassa-998	192	6	e	e	NOUN
ijassa-998	192	7	the	the	DET
ijassa-998	192	8	strong	strong	ADJ
ijassa-998	192	9	inequality	inequality	NOUN
ijassa-998	192	10	in	in	ADP
ijassa-998	192	11	the	the	DET
ijassa-998	192	12	last	last	ADJ
ijassa-998	192	13	expression	expression	NOUN
ijassa-998	192	14	can	can	AUX
ijassa-998	192	15	not	not	PART
ijassa-998	192	16	appear	appear	VERB
ijassa-998	192	17	.	.	PUNCT
ijassa-998	193	1	the	the	DET
ijassa-998	193	2	last	last	ADJ
ijassa-998	193	3	expression	expression	NOUN
ijassa-998	193	4	in	in	ADP
ijassa-998	193	5	(	(	PUNCT
ijassa-998	193	6	4.12	4.12	NUM
ijassa-998	193	7	)	)	PUNCT
ijassa-998	193	8	gives	give	VERB
ijassa-998	193	9	the	the	DET
ijassa-998	193	10	necessary	necessary	ADJ
ijassa-998	193	11	condition	condition	NOUN
ijassa-998	193	12	for	for	ADP
ijassa-998	193	13	h	h	NOUN
ijassa-998	193	14	on	on	ADP
ijassa-998	193	15	the	the	DET
ijassa-998	193	16	constraint	constraint	NOUN
ijassa-998	193	17	boundary	boundary	NOUN
ijassa-998	193	18	,	,	PUNCT
ijassa-998	193	19	which	which	PRON
ijassa-998	193	20	guarantees	guarantee	VERB
ijassa-998	193	21	an	an	DET
ijassa-998	193	22	admissible	admissible	ADJ
ijassa-998	193	23	process	process	NOUN
ijassa-998	193	24	.	.	PUNCT
ijassa-998	194	1	therefore	therefore	ADV
ijassa-998	194	2	the	the	DET
ijassa-998	194	3	following	follow	VERB
ijassa-998	194	4	analysis	analysis	NOUN
ijassa-998	194	5	is	be	AUX
ijassa-998	194	6	needed	need	VERB
ijassa-998	194	7	.	.	PUNCT
ijassa-998	195	1	from	from	ADP
ijassa-998	195	2	the	the	DET
ijassa-998	195	3	last	last	ADJ
ijassa-998	195	4	equation	equation	NOUN
ijassa-998	195	5	of	of	ADP
ijassa-998	195	6	the	the	DET
ijassa-998	195	7	system	system	NOUN
ijassa-998	195	8	(	(	PUNCT
ijassa-998	195	9	3.4	3.4	NUM
ijassa-998	195	10	)	)	PUNCT
ijassa-998	195	11	holds	hold	VERB
ijassa-998	195	12	for	for	ADP
ijassa-998	195	13	u(t	u(t	NOUN
ijassa-998	195	14	)	)	PUNCT
ijassa-998	195	15	=	=	PRON
ijassa-998	196	1	umax	umax	PROPN
ijassa-998	196	2	h(tj	h(tj	NUM
ijassa-998	196	3	)	)	PUNCT
ijassa-998	196	4	=	=	PRON
ijassa-998	197	1	e−γtj	e−γtj	VERB
ijassa-998	197	2	∫	∫	PROPN
ijassa-998	197	3	tj	tj	PROPN
ijassa-998	197	4	0	0	PROPN
ijassa-998	197	5	eγtumaxdt	eγtumaxdt	NOUN
ijassa-998	197	6	=	=	SYM
ijassa-998	197	7	umax	umax	PROPN
ijassa-998	197	8	γ	γ	X
ijassa-998	197	9	(	(	PUNCT
ijassa-998	197	10	1−	1−	NUM
ijassa-998	197	11	e−γtj	e−γtj	PROPN
ijassa-998	197	12	)	)	PUNCT
ijassa-998	197	13	.	.	PUNCT
ijassa-998	198	1	(	(	PUNCT
ijassa-998	198	2	4.13	4.13	NUM
ijassa-998	198	3	)	)	PUNCT
ijassa-998	198	4	thus	thus	ADV
ijassa-998	199	1	if	if	SCONJ
ijassa-998	199	2	the	the	DET
ijassa-998	199	3	maximal	maximal	ADJ
ijassa-998	199	4	amount	amount	NOUN
ijassa-998	199	5	of	of	ADP
ijassa-998	199	6	the	the	DET
ijassa-998	199	7	drug	drug	NOUN
ijassa-998	199	8	,	,	PUNCT
ijassa-998	199	9	u(t	u(t	PROPN
ijassa-998	199	10	)	)	PUNCT
ijassa-998	199	11	=	=	PUNCT
ijassa-998	199	12	umax	umax	PROPN
ijassa-998	199	13	,	,	PUNCT
ijassa-998	199	14	t	t	PROPN
ijassa-998	199	15	∈	∈	PROPN
ijassa-998	200	1	[	[	X
ijassa-998	200	2	0	0	NUM
ijassa-998	200	3	,	,	PUNCT
ijassa-998	200	4	tj	tj	NOUN
ijassa-998	200	5	)	)	PUNCT
ijassa-998	200	6	,	,	PUNCT
ijassa-998	200	7	is	be	AUX
ijassa-998	200	8	administered	administer	VERB
ijassa-998	200	9	until	until	SCONJ
ijassa-998	200	10	the	the	DET
ijassa-998	200	11	critical	critical	ADJ
ijassa-998	200	12	boundary	boundary	NOUN
ijassa-998	200	13	of	of	ADP
ijassa-998	200	14	the	the	DET
ijassa-998	200	15	healthy	healthy	ADJ
ijassa-998	200	16	cells	cell	NOUN
ijassa-998	200	17	is	be	AUX
ijassa-998	200	18	reached	reach	VERB
ijassa-998	200	19	,	,	PUNCT
ijassa-998	200	20	the	the	DET
ijassa-998	200	21	following	follow	VERB
ijassa-998	200	22	relation	relation	NOUN
ijassa-998	200	23	has	have	VERB
ijassa-998	200	24	to	to	PART
ijassa-998	200	25	be	be	AUX
ijassa-998	200	26	fulfilled	fulfil	VERB
ijassa-998	200	27	(	(	PUNCT
ijassa-998	200	28	1−	1−	NUM
ijassa-998	200	29	εz(tj	εz(tj	PROPN
ijassa-998	200	30	)	)	PUNCT
ijassa-998	201	1	+	+	CCONJ
ijassa-998	201	2	δeηe	δeηe	X
ijassa-998	201	3	(	(	PUNCT
ijassa-998	201	4	ηe	ηe	ADP
ijassa-998	201	5	−	−	PROPN
ijassa-998	201	6	ec)µ0	ec)µ0	PROPN
ijassa-998	201	7	e	e	PROPN
ijassa-998	201	8	)	)	PUNCT
ijassa-998	201	9	ke	ke	NOUN
ijassa-998	201	10	−	−	PROPN
ijassa-998	202	1	(	(	PUNCT
ijassa-998	202	2	1−	1−	NUM
ijassa-998	202	3	εz(tj	εz(tj	PROPN
ijassa-998	202	4	)	)	PUNCT
ijassa-998	203	1	+	+	CCONJ
ijassa-998	203	2	δeηe	δeηe	X
ijassa-998	203	3	(	(	PUNCT
ijassa-998	203	4	ηe	ηe	ADP
ijassa-998	203	5	−	−	PROPN
ijassa-998	203	6	ec)µ0	ec)µ0	PROPN
ijassa-998	203	7	e	e	NOUN
ijassa-998	203	8	)	)	PUNCT
ijassa-998	204	1	=	=	VERB
ijassa-998	204	2	umax	umax	VERB
ijassa-998	204	3	γ	γ	X
ijassa-998	204	4	(	(	PUNCT
ijassa-998	204	5	1−	1−	NUM
ijassa-998	204	6	e−γtj	e−γtj	ADJ
ijassa-998	204	7	)	)	PUNCT
ijassa-998	204	8	.	.	PUNCT
ijassa-998	205	1	(	(	PUNCT
ijassa-998	205	2	4.14	4.14	NUM
ijassa-998	205	3	)	)	PUNCT
ijassa-998	205	4	note	note	NOUN
ijassa-998	205	5	,	,	PUNCT
ijassa-998	205	6	that	that	SCONJ
ijassa-998	205	7	this	this	PRON
ijassa-998	205	8	is	be	AUX
ijassa-998	205	9	a	a	DET
ijassa-998	205	10	special	special	ADJ
ijassa-998	205	11	case	case	NOUN
ijassa-998	205	12	which	which	PRON
ijassa-998	205	13	can	can	AUX
ijassa-998	205	14	only	only	ADV
ijassa-998	205	15	appear	appear	VERB
ijassa-998	205	16	with	with	ADP
ijassa-998	205	17	a	a	DET
ijassa-998	205	18	given	give	VERB
ijassa-998	205	19	set	set	NOUN
ijassa-998	205	20	of	of	ADP
ijassa-998	205	21	parameters	parameter	NOUN
ijassa-998	205	22	of	of	ADP
ijassa-998	205	23	the	the	DET
ijassa-998	205	24	model	model	NOUN
ijassa-998	205	25	and	and	CCONJ
ijassa-998	205	26	initial	initial	ADJ
ijassa-998	205	27	conditions	condition	NOUN
ijassa-998	205	28	.	.	PUNCT
ijassa-998	206	1	in	in	ADP
ijassa-998	206	2	this	this	DET
ijassa-998	206	3	case	case	NOUN
ijassa-998	206	4	the	the	DET
ijassa-998	206	5	therapy	therapy	NOUN
ijassa-998	206	6	strategy	strategy	NOUN
ijassa-998	206	7	can	can	AUX
ijassa-998	206	8	be	be	AUX
ijassa-998	206	9	changed	change	VERB
ijassa-998	206	10	when	when	SCONJ
ijassa-998	206	11	the	the	DET
ijassa-998	206	12	amount	amount	NOUN
ijassa-998	206	13	of	of	ADP
ijassa-998	206	14	the	the	DET
ijassa-998	206	15	healthy	healthy	ADJ
ijassa-998	206	16	cells	cell	NOUN
ijassa-998	206	17	reaches	reach	VERB
ijassa-998	206	18	the	the	DET
ijassa-998	206	19	critical	critical	ADJ
ijassa-998	206	20	value	value	NOUN
ijassa-998	206	21	without	without	ADP
ijassa-998	206	22	violating	violate	VERB
ijassa-998	206	23	the	the	DET
ijassa-998	206	24	therapy	therapy	NOUN
ijassa-998	206	25	process	process	NOUN
ijassa-998	206	26	.	.	PUNCT
ijassa-998	207	1	the	the	DET
ijassa-998	207	2	therapy	therapy	NOUN
ijassa-998	207	3	strategy	strategy	NOUN
ijassa-998	207	4	stated	state	VERB
ijassa-998	207	5	below	below	ADV
ijassa-998	207	6	is	be	AUX
ijassa-998	207	7	in	in	ADP
ijassa-998	207	8	this	this	DET
ijassa-998	207	9	case	case	NOUN
ijassa-998	207	10	optimal	optimal	ADJ
ijassa-998	207	11	(	(	PUNCT
ijassa-998	207	12	see	see	VERB
ijassa-998	207	13	a.4	a.4	NOUN
ijassa-998	207	14	)	)	PUNCT
ijassa-998	207	15	.	.	PUNCT
ijassa-998	208	1	copyright	copyright	NOUN
ijassa-998	208	2	c	c	ADP
ijassa-998	208	3	©	©	PROPN
ijassa-998	208	4	2020	2020	NUM
ijassa-998	208	5	assa	assa	NOUN
ijassa-998	208	6	.	.	PUNCT
ijassa-998	209	1	adv	adv	PROPN
ijassa-998	209	2	syst	syst	PROPN
ijassa-998	209	3	sci	sci	PROPN
ijassa-998	209	4	appl	appl	PROPN
ijassa-998	209	5	(	(	PUNCT
ijassa-998	209	6	2020	2020	NUM
ijassa-998	209	7	)	)	PUNCT
ijassa-998	209	8	94	94	NUM
ijassa-998	209	9	m.-c	m.-c	NOUN
ijassa-998	209	10	.	.	PUNCT
ijassa-998	210	1	litzinger	litzinger	NOUN
ijassa-998	210	2	,	,	PUNCT
ijassa-998	210	3	y.	y.	PROPN
ijassa-998	210	4	todorov	todorov	PROPN
ijassa-998	210	5	,	,	PUNCT
ijassa-998	210	6	m.	m.	NOUN
ijassa-998	210	7	föller	föller	PROPN
ijassa-998	210	8	-	-	PUNCT
ijassa-998	210	9	nord	nord	PROPN
ijassa-998	210	10	,	,	PUNCT
ijassa-998	210	11	m.k	m.k	PROPN
ijassa-998	210	12	.	.	PUNCT
ijassa-998	210	13	chaudhary	chaudhary	PROPN
ijassa-998	210	14	,	,	PUNCT
ijassa-998	210	15	a.s	a.s	PROPN
ijassa-998	210	16	.	.	PROPN
ijassa-998	210	17	bratus	bratus	PROPN
ijassa-998	210	18	u(t	u(t	PROPN
ijassa-998	210	19	)	)	PUNCT
ijassa-998	210	20	=	=	SYM
ijassa-998	210	21			NUM
ijassa-998	210	22	umax	umax	PROPN
ijassa-998	210	23	,	,	PUNCT
ijassa-998	210	24	0	0	NUM
ijassa-998	210	25	≤	≤	NUM
ijassa-998	210	26	t	t	PROPN
ijassa-998	210	27	≤	≤	NUM
ijassa-998	210	28	tj	tj	NOUN
ijassa-998	210	29	,	,	PUNCT
ijassa-998	210	30	γ	γ	X
ijassa-998	210	31	1−	1−	ADV
ijassa-998	210	32	εz(t	εz(t	NOUN
ijassa-998	210	33	)	)	PUNCT
ijassa-998	210	34	+	+	CCONJ
ijassa-998	210	35	δeηe	δeηe	X
ijassa-998	210	36	(	(	PUNCT
ijassa-998	210	37	ηe	ηe	ADP
ijassa-998	210	38	−	−	PROPN
ijassa-998	210	39	ec)µ0	ec)µ0	PROPN
ijassa-998	210	40	e	e	NOUN
ijassa-998	210	41			PROPN
ijassa-998	210	42	ke−	ke−	PROPN
ijassa-998	210	43	1−	1−	NOUN
ijassa-998	210	44	εz(t	εz(t	NOUN
ijassa-998	210	45	)	)	PUNCT
ijassa-998	211	1	+	+	CCONJ
ijassa-998	211	2	δeηe	δeηe	X
ijassa-998	211	3	(	(	PUNCT
ijassa-998	211	4	ηe	ηe	ADP
ijassa-998	211	5	−	−	PROPN
ijassa-998	211	6	ec)µ0	ec)µ0	PROPN
ijassa-998	211	7	e	e	X
ijassa-998	211	8			PROPN
ijassa-998	211	9	,	,	PUNCT
ijassa-998	211	10	tj	tj	X
ijassa-998	211	11	<	<	X
ijassa-998	211	12	t	t	X
ijassa-998	211	13	≤	≤	ADJ
ijassa-998	211	14	t.	t.	NOUN
ijassa-998	211	15	(	(	PUNCT
ijassa-998	211	16	4.15	4.15	NUM
ijassa-998	211	17	)	)	PUNCT
ijassa-998	211	18	in	in	ADP
ijassa-998	211	19	general	general	ADJ
ijassa-998	211	20	the	the	DET
ijassa-998	211	21	change	change	NOUN
ijassa-998	211	22	of	of	ADP
ijassa-998	211	23	the	the	DET
ijassa-998	211	24	administered	administer	VERB
ijassa-998	211	25	amount	amount	NOUN
ijassa-998	211	26	of	of	ADP
ijassa-998	211	27	the	the	DET
ijassa-998	211	28	drug	drug	NOUN
ijassa-998	211	29	can	can	AUX
ijassa-998	211	30	not	not	PART
ijassa-998	211	31	induce	induce	VERB
ijassa-998	211	32	the	the	DET
ijassa-998	211	33	change	change	NOUN
ijassa-998	211	34	of	of	ADP
ijassa-998	211	35	the	the	DET
ijassa-998	211	36	slope	slope	NOUN
ijassa-998	211	37	of	of	ADP
ijassa-998	211	38	the	the	DET
ijassa-998	211	39	development	development	NOUN
ijassa-998	211	40	of	of	ADP
ijassa-998	211	41	the	the	DET
ijassa-998	211	42	healthy	healthy	ADJ
ijassa-998	211	43	cells	cell	NOUN
ijassa-998	211	44	immediately	immediately	ADV
ijassa-998	211	45	.	.	PUNCT
ijassa-998	212	1	this	this	PRON
ijassa-998	212	2	is	be	AUX
ijassa-998	212	3	caused	cause	VERB
ijassa-998	212	4	by	by	ADP
ijassa-998	212	5	the	the	DET
ijassa-998	212	6	inertia	inertia	NOUN
ijassa-998	212	7	of	of	ADP
ijassa-998	212	8	the	the	DET
ijassa-998	212	9	dynamic	dynamic	ADJ
ijassa-998	212	10	system	system	NOUN
ijassa-998	212	11	.	.	PUNCT
ijassa-998	213	1	therefore	therefore	ADV
ijassa-998	213	2	investigations	investigation	NOUN
ijassa-998	213	3	of	of	ADP
ijassa-998	213	4	the	the	DET
ijassa-998	213	5	more	more	ADV
ijassa-998	213	6	realistic	realistic	ADJ
ijassa-998	213	7	cases	case	NOUN
ijassa-998	213	8	have	have	VERB
ijassa-998	213	9	to	to	PART
ijassa-998	213	10	be	be	AUX
ijassa-998	213	11	done	do	VERB
ijassa-998	213	12	.	.	PUNCT
ijassa-998	214	1	the	the	DET
ijassa-998	214	2	case	case	NOUN
ijassa-998	214	3	in	in	ADP
ijassa-998	214	4	which	which	PRON
ijassa-998	214	5	the	the	DET
ijassa-998	214	6	maximal	maximal	ADJ
ijassa-998	214	7	admissible	admissible	ADJ
ijassa-998	214	8	amount	amount	NOUN
ijassa-998	214	9	of	of	ADP
ijassa-998	214	10	the	the	DET
ijassa-998	214	11	drug	drug	NOUN
ijassa-998	214	12	has	have	VERB
ijassa-998	214	13	to	to	PART
ijassa-998	214	14	be	be	AUX
ijassa-998	214	15	changed	change	VERB
ijassa-998	214	16	before	before	SCONJ
ijassa-998	214	17	the	the	DET
ijassa-998	214	18	critical	critical	ADJ
ijassa-998	214	19	boundary	boundary	NOUN
ijassa-998	214	20	of	of	ADP
ijassa-998	214	21	the	the	DET
ijassa-998	214	22	healthy	healthy	ADJ
ijassa-998	214	23	cells	cell	NOUN
ijassa-998	214	24	is	be	AUX
ijassa-998	214	25	reached	reach	VERB
ijassa-998	214	26	,	,	PUNCT
ijassa-998	214	27	is	be	AUX
ijassa-998	214	28	considered	consider	VERB
ijassa-998	214	29	.	.	PUNCT
ijassa-998	215	1	i.e.	i.e.	X
ijassa-998	215	2	,	,	PUNCT
ijassa-998	215	3	(	(	PUNCT
ijassa-998	215	4	1−	1−	NUM
ijassa-998	215	5	εz(tj	εz(tj	PROPN
ijassa-998	215	6	)	)	PUNCT
ijassa-998	216	1	+	+	CCONJ
ijassa-998	216	2	δeηe	δeηe	X
ijassa-998	216	3	(	(	PUNCT
ijassa-998	216	4	ηe	ηe	ADP
ijassa-998	216	5	−	−	PROPN
ijassa-998	216	6	ec)µ0	ec)µ0	PROPN
ijassa-998	216	7	e	e	PROPN
ijassa-998	216	8	)	)	PUNCT
ijassa-998	216	9	ke	ke	NOUN
ijassa-998	216	10	−	−	PROPN
ijassa-998	217	1	(	(	PUNCT
ijassa-998	217	2	1−	1−	NUM
ijassa-998	217	3	εz(tj	εz(tj	PROPN
ijassa-998	217	4	)	)	PUNCT
ijassa-998	218	1	+	+	CCONJ
ijassa-998	218	2	δeηe	δeηe	X
ijassa-998	218	3	(	(	PUNCT
ijassa-998	218	4	ηe	ηe	ADP
ijassa-998	218	5	−	−	PROPN
ijassa-998	218	6	ec)µ0	ec)µ0	PROPN
ijassa-998	218	7	e	e	PROPN
ijassa-998	218	8	)	)	PUNCT
ijassa-998	218	9	<	<	X
ijassa-998	218	10	umax	umax	PROPN
ijassa-998	218	11	γ	γ	X
ijassa-998	218	12	(	(	PUNCT
ijassa-998	218	13	1−	1−	NUM
ijassa-998	218	14	e−γtj	e−γtj	ADJ
ijassa-998	218	15	)	)	PUNCT
ijassa-998	218	16	.	.	PUNCT
ijassa-998	219	1	(	(	PUNCT
ijassa-998	219	2	4.16	4.16	NUM
ijassa-998	219	3	)	)	PUNCT
ijassa-998	219	4	the	the	DET
ijassa-998	219	5	admissible	admissible	ADJ
ijassa-998	219	6	process	process	NOUN
ijassa-998	219	7	can	can	AUX
ijassa-998	219	8	be	be	AUX
ijassa-998	219	9	guaranteed	guarantee	VERB
ijassa-998	219	10	if	if	SCONJ
ijassa-998	219	11	the	the	DET
ijassa-998	219	12	maximal	maximal	ADJ
ijassa-998	219	13	admissible	admissible	ADJ
ijassa-998	219	14	amount	amount	NOUN
ijassa-998	219	15	of	of	ADP
ijassa-998	219	16	the	the	DET
ijassa-998	219	17	drug	drug	NOUN
ijassa-998	219	18	is	be	AUX
ijassa-998	219	19	reduced	reduce	VERB
ijassa-998	219	20	at	at	ADP
ijassa-998	219	21	the	the	DET
ijassa-998	219	22	point	point	NOUN
ijassa-998	219	23	of	of	ADP
ijassa-998	219	24	time	time	NOUN
ijassa-998	219	25	t′	t′	X
ijassa-998	219	26	<	<	X
ijassa-998	219	27	tj	tj	NOUN
ijassa-998	219	28	so	so	SCONJ
ijassa-998	219	29	that	that	SCONJ
ijassa-998	219	30	h(t′	h(t′	NUM
ijassa-998	219	31	)	)	PUNCT
ijassa-998	219	32	=	=	PRON
ijassa-998	219	33	(	(	PUNCT
ijassa-998	219	34	1−	1−	NUM
ijassa-998	219	35	εz(tj(umax	εz(tj(umax	PROPN
ijassa-998	219	36	)	)	PUNCT
ijassa-998	219	37	)	)	PUNCT
ijassa-998	220	1	+	+	CCONJ
ijassa-998	220	2	δeηe	δeηe	X
ijassa-998	220	3	(	(	PUNCT
ijassa-998	220	4	ηe	ηe	ADP
ijassa-998	220	5	−	−	PROPN
ijassa-998	220	6	ec)µ0	ec)µ0	PROPN
ijassa-998	220	7	e	e	PROPN
ijassa-998	220	8	)	)	PUNCT
ijassa-998	220	9	ke	ke	NOUN
ijassa-998	220	10	−	−	PROPN
ijassa-998	221	1	(	(	PUNCT
ijassa-998	221	2	1−	1−	NUM
ijassa-998	221	3	εz(tj(umax	εz(tj(umax	PROPN
ijassa-998	221	4	)	)	PUNCT
ijassa-998	221	5	)	)	PUNCT
ijassa-998	222	1	+	+	CCONJ
ijassa-998	222	2	δeηe	δeηe	X
ijassa-998	222	3	(	(	PUNCT
ijassa-998	222	4	ηe	ηe	ADP
ijassa-998	222	5	−	−	PROPN
ijassa-998	222	6	ec)µ0	ec)µ0	PROPN
ijassa-998	222	7	e	e	PROPN
ijassa-998	222	8	)	)	PUNCT
ijassa-998	222	9	holds	hold	VERB
ijassa-998	222	10	,	,	PUNCT
ijassa-998	222	11	where	where	SCONJ
ijassa-998	222	12	z(tj(umax	z(tj(umax	NOUN
ijassa-998	222	13	)	)	PUNCT
ijassa-998	222	14	)	)	PUNCT
ijassa-998	222	15	is	be	AUX
ijassa-998	222	16	the	the	DET
ijassa-998	222	17	amount	amount	NOUN
ijassa-998	222	18	of	of	ADP
ijassa-998	222	19	the	the	DET
ijassa-998	222	20	cancer	cancer	NOUN
ijassa-998	222	21	cells	cell	NOUN
ijassa-998	222	22	on	on	ADP
ijassa-998	222	23	the	the	DET
ijassa-998	222	24	constraint	constraint	NOUN
ijassa-998	222	25	boundary	boundary	NOUN
ijassa-998	222	26	using	use	VERB
ijassa-998	222	27	the	the	DET
ijassa-998	222	28	maximal	maximal	ADJ
ijassa-998	222	29	dose	dose	NOUN
ijassa-998	222	30	of	of	ADP
ijassa-998	222	31	medicine	medicine	NOUN
ijassa-998	222	32	(	(	PUNCT
ijassa-998	222	33	u(t	u(t	PROPN
ijassa-998	222	34	)	)	PUNCT
ijassa-998	223	1	=	=	PUNCT
ijassa-998	223	2	umax	umax	PROPN
ijassa-998	223	3	,	,	PUNCT
ijassa-998	223	4	t	t	PROPN
ijassa-998	223	5	∈	∈	PROPN
ijassa-998	224	1	[	[	X
ijassa-998	224	2	0	0	NUM
ijassa-998	224	3	,	,	PUNCT
ijassa-998	224	4	tj	tj	NOUN
ijassa-998	224	5	]	]	NOUN
ijassa-998	224	6	)	)	PUNCT
ijassa-998	224	7	.	.	PUNCT
ijassa-998	225	1	thus	thus	ADV
ijassa-998	225	2	the	the	DET
ijassa-998	225	3	suboptimal	suboptimal	ADJ
ijassa-998	225	4	therapy	therapy	NOUN
ijassa-998	225	5	strategy	strategy	NOUN
ijassa-998	225	6	can	can	AUX
ijassa-998	225	7	be	be	AUX
ijassa-998	225	8	given	give	VERB
ijassa-998	225	9	by	by	ADP
ijassa-998	225	10	u(t	u(t	NOUN
ijassa-998	225	11	)	)	PUNCT
ijassa-998	225	12	=	=	SYM
ijassa-998	226	1			NUM
ijassa-998	226	2	umax	umax	PROPN
ijassa-998	226	3	,	,	PUNCT
ijassa-998	226	4	0	0	NUM
ijassa-998	226	5	≤	≤	NUM
ijassa-998	226	6	t	t	X
ijassa-998	226	7	≤	≤	NUM
ijassa-998	226	8	t′	t′	NUM
ijassa-998	226	9	,	,	PUNCT
ijassa-998	226	10	γ	γ	X
ijassa-998	226	11	1−	1−	PRON
ijassa-998	226	12	εz(tj(umax	εz(tj(umax	PROPN
ijassa-998	226	13	)	)	PUNCT
ijassa-998	226	14	)	)	PUNCT
ijassa-998	227	1	+	+	CCONJ
ijassa-998	227	2	δeηe	δeηe	X
ijassa-998	227	3	(	(	PUNCT
ijassa-998	227	4	ηe	ηe	ADP
ijassa-998	227	5	−	−	NUM
ijassa-998	227	6	e(t))µ0	e(t))µ0	PRON
ijassa-998	227	7	e	e	X
ijassa-998	227	8			PROPN
ijassa-998	227	9	ke−	ke−	PROPN
ijassa-998	227	10	1−	1−	PRON
ijassa-998	227	11	εz(tj(umax	εz(tj(umax	PROPN
ijassa-998	227	12	)	)	PUNCT
ijassa-998	227	13	)	)	PUNCT
ijassa-998	228	1	+	+	CCONJ
ijassa-998	228	2	δeηe	δeηe	X
ijassa-998	228	3	(	(	PUNCT
ijassa-998	228	4	ηe	ηe	ADP
ijassa-998	228	5	−	−	PROPN
ijassa-998	228	6	e(t))µ0	e(t))µ0	NOUN
ijassa-998	228	7	e	e	X
ijassa-998	228	8			PROPN
ijassa-998	228	9	,	,	PUNCT
ijassa-998	228	10	t′	t′	NUM
ijassa-998	228	11	<	<	X
ijassa-998	228	12	t	t	X
ijassa-998	228	13	≤	≤	ADJ
ijassa-998	228	14	t.	t.	NOUN
ijassa-998	228	15	(	(	PUNCT
ijassa-998	228	16	4.17	4.17	NUM
ijassa-998	228	17	)	)	PUNCT
ijassa-998	228	18	the	the	DET
ijassa-998	228	19	following	follow	VERB
ijassa-998	228	20	figures	figure	NOUN
ijassa-998	228	21	present	present	VERB
ijassa-998	228	22	the	the	DET
ijassa-998	228	23	results	result	NOUN
ijassa-998	228	24	of	of	ADP
ijassa-998	228	25	the	the	DET
ijassa-998	228	26	suboptimal	suboptimal	ADJ
ijassa-998	228	27	control	control	PROPN
ijassa-998	228	28	approach	approach	NOUN
ijassa-998	228	29	.	.	PUNCT
ijassa-998	229	1	cancer	cancer	NOUN
ijassa-998	229	2	and	and	CCONJ
ijassa-998	229	3	healthy	healthy	ADJ
ijassa-998	229	4	cells	cell	NOUN
ijassa-998	229	5	decrease	decrease	NOUN
ijassa-998	229	6	and	and	CCONJ
ijassa-998	229	7	the	the	DET
ijassa-998	229	8	healthy	healthy	ADJ
ijassa-998	229	9	cells	cell	NOUN
ijassa-998	229	10	do	do	AUX
ijassa-998	229	11	not	not	PART
ijassa-998	229	12	reach	reach	VERB
ijassa-998	229	13	the	the	DET
ijassa-998	229	14	constraint	constraint	NOUN
ijassa-998	229	15	boundary	boundary	NOUN
ijassa-998	229	16	(	(	PUNCT
ijassa-998	229	17	fig	fig	NOUN
ijassa-998	229	18	.	.	PUNCT
ijassa-998	230	1	4.10	4.10	NUM
ijassa-998	230	2	)	)	PUNCT
ijassa-998	230	3	,	,	PUNCT
ijassa-998	230	4	(	(	PUNCT
ijassa-998	230	5	fig	fig	NOUN
ijassa-998	230	6	.	.	PUNCT
ijassa-998	231	1	4.11	4.11	NUM
ijassa-998	231	2	)	)	PUNCT
ijassa-998	231	3	.	.	PUNCT
ijassa-998	232	1	since	since	SCONJ
ijassa-998	232	2	cancer	cancer	NOUN
ijassa-998	232	3	cells	cell	NOUN
ijassa-998	232	4	are	be	AUX
ijassa-998	232	5	decreasing	decrease	VERB
ijassa-998	232	6	continuously	continuously	ADV
ijassa-998	232	7	the	the	DET
ijassa-998	232	8	quantity	quantity	NOUN
ijassa-998	232	9	of	of	ADP
ijassa-998	232	10	psa	psa	NOUN
ijassa-998	232	11	in	in	ADP
ijassa-998	232	12	the	the	DET
ijassa-998	232	13	tissue	tissue	NOUN
ijassa-998	232	14	and	and	CCONJ
ijassa-998	232	15	therefore	therefore	ADV
ijassa-998	232	16	in	in	ADP
ijassa-998	232	17	the	the	DET
ijassa-998	232	18	blood	blood	NOUN
ijassa-998	232	19	serum	serum	NOUN
ijassa-998	232	20	also	also	ADV
ijassa-998	232	21	decreases	decrease	VERB
ijassa-998	232	22	(	(	PUNCT
ijassa-998	232	23	fig	fig	NOUN
ijassa-998	232	24	.	.	PUNCT
ijassa-998	233	1	4.13	4.13	NUM
ijassa-998	233	2	)	)	PUNCT
ijassa-998	233	3	.	.	PUNCT
ijassa-998	234	1	5	5	X
ijassa-998	234	2	.	.	X
ijassa-998	234	3	optimal	optimal	ADJ
ijassa-998	234	4	therapy	therapy	NOUN
ijassa-998	234	5	strategy	strategy	NOUN
ijassa-998	234	6	in	in	ADP
ijassa-998	234	7	this	this	DET
ijassa-998	234	8	section	section	NOUN
ijassa-998	234	9	the	the	DET
ijassa-998	234	10	therapy	therapy	NOUN
ijassa-998	234	11	strategy	strategy	NOUN
ijassa-998	234	12	related	relate	VERB
ijassa-998	234	13	to	to	ADP
ijassa-998	234	14	the	the	DET
ijassa-998	234	15	optimal	optimal	ADJ
ijassa-998	234	16	control	control	NOUN
ijassa-998	234	17	problem	problem	NOUN
ijassa-998	234	18	(	(	PUNCT
ijassa-998	234	19	3.3)-(3.5	3.3)-(3.5	NUM
ijassa-998	234	20	)	)	PUNCT
ijassa-998	234	21	is	be	AUX
ijassa-998	234	22	investigated	investigate	VERB
ijassa-998	234	23	with	with	ADP
ijassa-998	234	24	pontryagin	pontryagin	NOUN
ijassa-998	234	25	’s	’s	PART
ijassa-998	234	26	maximum	maximum	ADJ
ijassa-998	234	27	principle	principle	NOUN
ijassa-998	234	28	,	,	PUNCT
ijassa-998	234	29	which	which	PRON
ijassa-998	234	30	is	be	AUX
ijassa-998	234	31	the	the	DET
ijassa-998	234	32	necessary	necessary	ADJ
ijassa-998	234	33	condition	condition	NOUN
ijassa-998	234	34	for	for	ADP
ijassa-998	234	35	an	an	DET
ijassa-998	234	36	optimal	optimal	ADJ
ijassa-998	234	37	process	process	NOUN
ijassa-998	234	38	.	.	PUNCT
ijassa-998	235	1	the	the	DET
ijassa-998	235	2	restriction	restriction	NOUN
ijassa-998	235	3	on	on	ADP
ijassa-998	235	4	the	the	DET
ijassa-998	235	5	minimal	minimal	ADJ
ijassa-998	235	6	admissible	admissible	ADJ
ijassa-998	235	7	amount	amount	NOUN
ijassa-998	235	8	of	of	ADP
ijassa-998	235	9	healthy	healthy	ADJ
ijassa-998	235	10	cells	cell	NOUN
ijassa-998	235	11	(	(	PUNCT
ijassa-998	235	12	3.5	3.5	NUM
ijassa-998	235	13	)	)	PUNCT
ijassa-998	235	14	has	have	VERB
ijassa-998	235	15	to	to	PART
ijassa-998	235	16	be	be	AUX
ijassa-998	235	17	interpreted	interpret	VERB
ijassa-998	235	18	as	as	ADP
ijassa-998	235	19	a	a	DET
ijassa-998	235	20	second	second	ADJ
ijassa-998	235	21	order	order	NOUN
ijassa-998	235	22	state	state	NOUN
ijassa-998	235	23	constraint	constraint	NOUN
ijassa-998	235	24	.	.	PUNCT
ijassa-998	236	1	because	because	SCONJ
ijassa-998	236	2	of	of	ADP
ijassa-998	236	3	the	the	DET
ijassa-998	236	4	high	high	ADJ
ijassa-998	236	5	complexity	complexity	NOUN
ijassa-998	236	6	of	of	ADP
ijassa-998	236	7	optimal	optimal	ADJ
ijassa-998	236	8	copyright	copyright	NOUN
ijassa-998	236	9	c	c	ADP
ijassa-998	236	10	©	©	PROPN
ijassa-998	236	11	2020	2020	NUM
ijassa-998	236	12	assa	assa	NOUN
ijassa-998	236	13	.	.	PUNCT
ijassa-998	237	1	adv	adv	PROPN
ijassa-998	237	2	syst	syst	PROPN
ijassa-998	237	3	sci	sci	PROPN
ijassa-998	237	4	appl	appl	PROPN
ijassa-998	237	5	(	(	PUNCT
ijassa-998	237	6	2020	2020	NUM
ijassa-998	237	7	)	)	PUNCT
ijassa-998	237	8	on	on	ADP
ijassa-998	237	9	optimal	optimal	ADJ
ijassa-998	237	10	therapy	therapy	NOUN
ijassa-998	237	11	protocols	protocol	NOUN
ijassa-998	237	12	in	in	ADP
ijassa-998	237	13	the	the	DET
ijassa-998	237	14	math	math	NOUN
ijassa-998	237	15	.	.	PUNCT
ijassa-998	238	1	model	model	NOUN
ijassa-998	238	2	of	of	ADP
ijassa-998	238	3	prostate	prostate	NOUN
ijassa-998	238	4	cancer	cancer	NOUN
ijassa-998	238	5	progression	progression	NOUN
ijassa-998	238	6	95	95	NUM
ijassa-998	238	7	0	0	NUM
ijassa-998	238	8	50	50	NUM
ijassa-998	238	9	100	100	NUM
ijassa-998	238	10	150	150	NUM
ijassa-998	238	11	non	non	ADJ
ijassa-998	238	12	-	-	ADJ
ijassa-998	238	13	dimensional	dimensional	ADJ
ijassa-998	238	14	time	time	NOUN
ijassa-998	238	15	44	44	NUM
ijassa-998	238	16	46	46	NUM
ijassa-998	238	17	48	48	NUM
ijassa-998	238	18	50	50	NUM
ijassa-998	238	19	52	52	NUM
ijassa-998	238	20	54	54	NUM
ijassa-998	238	21	56	56	NUM
ijassa-998	238	22	58	58	NUM
ijassa-998	238	23	fig	fig	NOUN
ijassa-998	238	24	.	.	PUNCT
ijassa-998	239	1	4.10	4.10	NUM
ijassa-998	239	2	.	.	PUNCT
ijassa-998	239	3	time	time	NOUN
ijassa-998	239	4	response	response	NOUN
ijassa-998	239	5	of	of	ADP
ijassa-998	239	6	healthy	healthy	ADJ
ijassa-998	239	7	cells	cell	NOUN
ijassa-998	239	8	e(t	e(t	NOUN
ijassa-998	239	9	)	)	PUNCT
ijassa-998	240	1	using	use	VERB
ijassa-998	240	2	the	the	DET
ijassa-998	240	3	suboptimal	suboptimal	ADJ
ijassa-998	240	4	therapy	therapy	NOUN
ijassa-998	240	5	strategy	strategy	NOUN
ijassa-998	240	6	0	0	NUM
ijassa-998	240	7	50	50	NUM
ijassa-998	240	8	100	100	NUM
ijassa-998	240	9	150	150	NUM
ijassa-998	240	10	non	non	ADJ
ijassa-998	240	11	-	-	ADJ
ijassa-998	240	12	dimensional	dimensional	ADJ
ijassa-998	240	13	time	time	NOUN
ijassa-998	240	14	120	120	NUM
ijassa-998	240	15	125	125	NUM
ijassa-998	240	16	130	130	NUM
ijassa-998	240	17	135	135	NUM
ijassa-998	240	18	140	140	NUM
ijassa-998	240	19	145	145	NUM
ijassa-998	240	20	150	150	NUM
ijassa-998	240	21	fig	fig	NOUN
ijassa-998	240	22	.	.	PUNCT
ijassa-998	241	1	4.11	4.11	NUM
ijassa-998	241	2	.	.	PUNCT
ijassa-998	241	3	time	time	NOUN
ijassa-998	241	4	response	response	NOUN
ijassa-998	241	5	of	of	ADP
ijassa-998	241	6	cancer	cancer	NOUN
ijassa-998	241	7	cells	cell	NOUN
ijassa-998	241	8	z(t	z(t	NOUN
ijassa-998	241	9	)	)	PUNCT
ijassa-998	241	10	using	use	VERB
ijassa-998	241	11	the	the	DET
ijassa-998	241	12	suboptimal	suboptimal	ADJ
ijassa-998	241	13	therapy	therapy	NOUN
ijassa-998	241	14	strategy	strategy	NOUN
ijassa-998	241	15	control	control	NOUN
ijassa-998	241	16	problems	problem	NOUN
ijassa-998	241	17	with	with	ADP
ijassa-998	241	18	higher	high	ADJ
ijassa-998	241	19	order	order	NOUN
ijassa-998	241	20	state	state	NOUN
ijassa-998	241	21	constraints	constraint	NOUN
ijassa-998	241	22	the	the	DET
ijassa-998	241	23	introduced	introduce	VERB
ijassa-998	241	24	approach	approach	NOUN
ijassa-998	241	25	is	be	AUX
ijassa-998	241	26	a	a	DET
ijassa-998	241	27	composition	composition	NOUN
ijassa-998	241	28	of	of	ADP
ijassa-998	241	29	analytical	analytical	ADJ
ijassa-998	241	30	investigations	investigation	NOUN
ijassa-998	241	31	and	and	CCONJ
ijassa-998	241	32	numerical	numerical	ADJ
ijassa-998	241	33	results	result	NOUN
ijassa-998	241	34	.	.	PUNCT
ijassa-998	242	1	copyright	copyright	NOUN
ijassa-998	242	2	c	c	ADP
ijassa-998	242	3	©	©	PROPN
ijassa-998	242	4	2020	2020	NUM
ijassa-998	242	5	assa	assa	NOUN
ijassa-998	242	6	.	.	PUNCT
ijassa-998	243	1	adv	adv	PROPN
ijassa-998	243	2	syst	syst	PROPN
ijassa-998	243	3	sci	sci	PROPN
ijassa-998	243	4	appl	appl	PROPN
ijassa-998	243	5	(	(	PUNCT
ijassa-998	243	6	2020	2020	NUM
ijassa-998	243	7	)	)	PUNCT
ijassa-998	243	8	96	96	NUM
ijassa-998	243	9	m.-c	m.-c	NOUN
ijassa-998	243	10	.	.	PUNCT
ijassa-998	244	1	litzinger	litzinger	NOUN
ijassa-998	244	2	,	,	PUNCT
ijassa-998	244	3	y.	y.	PROPN
ijassa-998	244	4	todorov	todorov	PROPN
ijassa-998	244	5	,	,	PUNCT
ijassa-998	244	6	m.	m.	NOUN
ijassa-998	244	7	föller	föller	PROPN
ijassa-998	244	8	-	-	PUNCT
ijassa-998	244	9	nord	nord	PROPN
ijassa-998	244	10	,	,	PUNCT
ijassa-998	244	11	m.k	m.k	PROPN
ijassa-998	244	12	.	.	PUNCT
ijassa-998	244	13	chaudhary	chaudhary	PROPN
ijassa-998	244	14	,	,	PUNCT
ijassa-998	244	15	a.s	a.s	PROPN
ijassa-998	244	16	.	.	PROPN
ijassa-998	244	17	bratus	bratus	PROPN
ijassa-998	244	18	0	0	NUM
ijassa-998	244	19	50	50	NUM
ijassa-998	244	20	100	100	NUM
ijassa-998	244	21	150	150	NUM
ijassa-998	244	22	non	non	ADJ
ijassa-998	244	23	-	-	ADJ
ijassa-998	244	24	dimensional	dimensional	ADJ
ijassa-998	244	25	time	time	NOUN
ijassa-998	244	26	0	0	NUM
ijassa-998	244	27	0.5	0.5	NUM
ijassa-998	244	28	1	1	NUM
ijassa-998	244	29	1.5	1.5	NUM
ijassa-998	244	30	2	2	NUM
ijassa-998	244	31	2.5	2.5	NUM
ijassa-998	244	32	3	3	NUM
ijassa-998	244	33	3.5	3.5	NUM
ijassa-998	244	34	4	4	NUM
ijassa-998	244	35	4.5	4.5	NUM
ijassa-998	244	36	5	5	NUM
ijassa-998	244	37	fig	fig	NOUN
ijassa-998	244	38	.	.	PUNCT
ijassa-998	245	1	4.12	4.12	NUM
ijassa-998	245	2	.	.	NOUN
ijassa-998	245	3	time	time	NOUN
ijassa-998	245	4	response	response	NOUN
ijassa-998	245	5	of	of	ADP
ijassa-998	245	6	the	the	DET
ijassa-998	245	7	quantity	quantity	NOUN
ijassa-998	245	8	of	of	ADP
ijassa-998	245	9	the	the	DET
ijassa-998	245	10	u(t	u(t	NOUN
ijassa-998	245	11	)	)	PUNCT
ijassa-998	245	12	using	use	VERB
ijassa-998	245	13	the	the	DET
ijassa-998	245	14	suboptimal	suboptimal	ADJ
ijassa-998	245	15	therapy	therapy	NOUN
ijassa-998	245	16	strategy	strategy	NOUN
ijassa-998	245	17	0	0	NUM
ijassa-998	245	18	50	50	NUM
ijassa-998	245	19	100	100	NUM
ijassa-998	245	20	150	150	NUM
ijassa-998	245	21	non	non	ADJ
ijassa-998	245	22	-	-	ADJ
ijassa-998	245	23	dimensional	dimensional	ADJ
ijassa-998	245	24	time	time	NOUN
ijassa-998	245	25	0	0	NUM
ijassa-998	245	26	1	1	NUM
ijassa-998	245	27	2	2	NUM
ijassa-998	245	28	3	3	NUM
ijassa-998	245	29	4	4	NUM
ijassa-998	245	30	5	5	NUM
ijassa-998	245	31	6	6	NUM
ijassa-998	245	32	7	7	NUM
ijassa-998	245	33	8	8	NUM
ijassa-998	245	34	9	9	NUM
ijassa-998	245	35	10	10	NUM
ijassa-998	245	36	fig	fig	NOUN
ijassa-998	245	37	.	.	PUNCT
ijassa-998	246	1	4.13	4.13	NUM
ijassa-998	246	2	.	.	PUNCT
ijassa-998	246	3	time	time	NOUN
ijassa-998	246	4	response	response	NOUN
ijassa-998	246	5	of	of	ADP
ijassa-998	246	6	the	the	DET
ijassa-998	246	7	psa	psa	NOUN
ijassa-998	246	8	function	function	PROPN
ijassa-998	246	9	p	p	PROPN
ijassa-998	246	10	(	(	PUNCT
ijassa-998	246	11	t	t	NOUN
ijassa-998	246	12	)	)	PUNCT
ijassa-998	246	13	using	use	VERB
ijassa-998	246	14	the	the	DET
ijassa-998	246	15	suboptimal	suboptimal	ADJ
ijassa-998	246	16	therapy	therapy	NOUN
ijassa-998	246	17	strategy	strategy	NOUN
ijassa-998	246	18	because	because	SCONJ
ijassa-998	246	19	of	of	ADP
ijassa-998	246	20	the	the	DET
ijassa-998	246	21	nature	nature	NOUN
ijassa-998	246	22	of	of	ADP
ijassa-998	246	23	the	the	DET
ijassa-998	246	24	maximum	maximum	ADJ
ijassa-998	246	25	principle	principle	NOUN
ijassa-998	246	26	it	it	PRON
ijassa-998	246	27	is	be	AUX
ijassa-998	246	28	essential	essential	ADJ
ijassa-998	246	29	to	to	PART
ijassa-998	246	30	primarily	primarily	ADV
ijassa-998	246	31	investigate	investigate	VERB
ijassa-998	246	32	the	the	DET
ijassa-998	246	33	optimal	optimal	ADJ
ijassa-998	246	34	therapy	therapy	NOUN
ijassa-998	246	35	strategy	strategy	NOUN
ijassa-998	246	36	without	without	ADP
ijassa-998	246	37	state	state	NOUN
ijassa-998	246	38	constraints	constraint	NOUN
ijassa-998	246	39	.	.	PUNCT
ijassa-998	247	1	the	the	DET
ijassa-998	247	2	optimality	optimality	NOUN
ijassa-998	247	3	of	of	ADP
ijassa-998	247	4	this	this	DET
ijassa-998	247	5	process	process	NOUN
ijassa-998	247	6	till	till	SCONJ
ijassa-998	247	7	the	the	DET
ijassa-998	247	8	state	state	NOUN
ijassa-998	247	9	variable	variable	NOUN
ijassa-998	247	10	e	e	PROPN
ijassa-998	247	11	reaches	reach	VERB
ijassa-998	247	12	the	the	DET
ijassa-998	247	13	constraint	constraint	NOUN
ijassa-998	247	14	boundary	boundary	NOUN
ijassa-998	247	15	is	be	AUX
ijassa-998	247	16	determined	determine	VERB
ijassa-998	247	17	.	.	PUNCT
ijassa-998	248	1	copyright	copyright	NOUN
ijassa-998	248	2	c	c	ADP
ijassa-998	248	3	©	©	PROPN
ijassa-998	248	4	2020	2020	NUM
ijassa-998	248	5	assa	assa	NOUN
ijassa-998	248	6	.	.	PUNCT
ijassa-998	249	1	adv	adv	PROPN
ijassa-998	249	2	syst	syst	PROPN
ijassa-998	249	3	sci	sci	PROPN
ijassa-998	249	4	appl	appl	PROPN
ijassa-998	249	5	(	(	PUNCT
ijassa-998	249	6	2020	2020	NUM
ijassa-998	249	7	)	)	PUNCT
ijassa-998	249	8	on	on	ADP
ijassa-998	249	9	optimal	optimal	ADJ
ijassa-998	249	10	therapy	therapy	NOUN
ijassa-998	249	11	protocols	protocol	NOUN
ijassa-998	249	12	in	in	ADP
ijassa-998	249	13	the	the	DET
ijassa-998	249	14	math	math	NOUN
ijassa-998	249	15	.	.	PUNCT
ijassa-998	250	1	model	model	NOUN
ijassa-998	250	2	of	of	ADP
ijassa-998	250	3	prostate	prostate	NOUN
ijassa-998	250	4	cancer	cancer	NOUN
ijassa-998	250	5	progression	progression	NOUN
ijassa-998	250	6	97	97	NUM
ijassa-998	250	7	the	the	DET
ijassa-998	250	8	investigations	investigation	NOUN
ijassa-998	250	9	given	give	VERB
ijassa-998	250	10	in	in	ADP
ijassa-998	250	11	a.3	a.3	NOUN
ijassa-998	250	12	prove	prove	VERB
ijassa-998	250	13	the	the	DET
ijassa-998	250	14	following	follow	VERB
ijassa-998	250	15	theorem	theorem	ADJ
ijassa-998	250	16	.	.	PUNCT
ijassa-998	250	17	theorem	theorem	VERB
ijassa-998	250	18	5.1	5.1	NUM
ijassa-998	250	19	:	:	PUNCT
ijassa-998	250	20	the	the	DET
ijassa-998	250	21	optimal	optimal	ADJ
ijassa-998	250	22	therapy	therapy	NOUN
ijassa-998	250	23	strategy	strategy	NOUN
ijassa-998	250	24	in	in	ADP
ijassa-998	250	25	the	the	DET
ijassa-998	250	26	absence	absence	NOUN
ijassa-998	250	27	of	of	ADP
ijassa-998	250	28	the	the	DET
ijassa-998	250	29	state	state	NOUN
ijassa-998	250	30	constraint	constraint	NOUN
ijassa-998	250	31	(	(	PUNCT
ijassa-998	250	32	3.5	3.5	NUM
ijassa-998	250	33	)	)	PUNCT
ijassa-998	250	34	is	be	AUX
ijassa-998	250	35	given	give	VERB
ijassa-998	250	36	as	as	ADP
ijassa-998	250	37	u∗(t	u∗(t	NOUN
ijassa-998	250	38	)	)	PUNCT
ijassa-998	250	39	=	=	VERB
ijassa-998	251	1	umax	umax	ADJ
ijassa-998	251	2	∀t	∀t	PROPN
ijassa-998	251	3	∈	∈	PROPN
ijassa-998	252	1	[	[	X
ijassa-998	252	2	0	0	NUM
ijassa-998	252	3	,	,	PUNCT
ijassa-998	252	4	t	t	X
ijassa-998	252	5	]	]	PUNCT
ijassa-998	252	6	.	.	PUNCT
ijassa-998	253	1	from	from	ADP
ijassa-998	253	2	the	the	DET
ijassa-998	253	3	practical	practical	ADJ
ijassa-998	253	4	point	point	NOUN
ijassa-998	253	5	of	of	ADP
ijassa-998	253	6	view	view	NOUN
ijassa-998	253	7	this	this	DET
ijassa-998	253	8	result	result	NOUN
ijassa-998	253	9	is	be	AUX
ijassa-998	253	10	equivalent	equivalent	ADJ
ijassa-998	253	11	to	to	ADP
ijassa-998	253	12	the	the	DET
ijassa-998	253	13	situation	situation	NOUN
ijassa-998	253	14	in	in	ADP
ijassa-998	253	15	which	which	PRON
ijassa-998	253	16	the	the	DET
ijassa-998	253	17	test	test	NOUN
ijassa-998	253	18	results	result	NOUN
ijassa-998	253	19	of	of	ADP
ijassa-998	253	20	a	a	DET
ijassa-998	253	21	patient	patient	NOUN
ijassa-998	253	22	are	be	AUX
ijassa-998	253	23	acceptable	acceptable	ADJ
ijassa-998	253	24	during	during	ADP
ijassa-998	253	25	the	the	DET
ijassa-998	253	26	therapy	therapy	NOUN
ijassa-998	253	27	.	.	PUNCT
ijassa-998	254	1	therefore	therefore	ADV
ijassa-998	254	2	the	the	DET
ijassa-998	254	3	therapy	therapy	NOUN
ijassa-998	254	4	has	have	VERB
ijassa-998	254	5	to	to	PART
ijassa-998	254	6	be	be	AUX
ijassa-998	254	7	executed	execute	VERB
ijassa-998	254	8	with	with	ADP
ijassa-998	254	9	the	the	DET
ijassa-998	254	10	maximal	maximal	ADJ
ijassa-998	254	11	admissible	admissible	ADJ
ijassa-998	254	12	amount	amount	NOUN
ijassa-998	254	13	of	of	ADP
ijassa-998	254	14	the	the	DET
ijassa-998	254	15	drug	drug	NOUN
ijassa-998	254	16	in	in	ADP
ijassa-998	254	17	order	order	NOUN
ijassa-998	254	18	to	to	PART
ijassa-998	254	19	eradicate	eradicate	VERB
ijassa-998	254	20	the	the	DET
ijassa-998	254	21	cancer	cancer	NOUN
ijassa-998	254	22	cells	cell	NOUN
ijassa-998	254	23	.	.	PUNCT
ijassa-998	255	1	in	in	ADP
ijassa-998	255	2	the	the	DET
ijassa-998	255	3	opposite	opposite	ADJ
ijassa-998	255	4	case	case	NOUN
ijassa-998	255	5	the	the	DET
ijassa-998	255	6	amount	amount	NOUN
ijassa-998	255	7	of	of	ADP
ijassa-998	255	8	healthy	healthy	ADJ
ijassa-998	255	9	cells	cell	NOUN
ijassa-998	255	10	e	e	NOUN
ijassa-998	255	11	reaches	reach	VERB
ijassa-998	255	12	the	the	DET
ijassa-998	255	13	critical	critical	ADJ
ijassa-998	255	14	value	value	NOUN
ijassa-998	255	15	ec	ec	PROPN
ijassa-998	255	16	.	.	PUNCT
ijassa-998	256	1	because	because	SCONJ
ijassa-998	256	2	of	of	ADP
ijassa-998	256	3	the	the	DET
ijassa-998	256	4	complexity	complexity	NOUN
ijassa-998	256	5	the	the	DET
ijassa-998	256	6	strict	strict	ADJ
ijassa-998	256	7	mathematical	mathematical	ADJ
ijassa-998	256	8	investigation	investigation	NOUN
ijassa-998	256	9	of	of	ADP
ijassa-998	256	10	the	the	DET
ijassa-998	256	11	constraint	constraint	NOUN
ijassa-998	256	12	problem	problem	NOUN
ijassa-998	256	13	is	be	AUX
ijassa-998	256	14	not	not	PART
ijassa-998	256	15	considered	consider	VERB
ijassa-998	256	16	.	.	PUNCT
ijassa-998	257	1	instead	instead	ADV
ijassa-998	257	2	of	of	ADP
ijassa-998	257	3	that	that	DET
ijassa-998	257	4	numerical	numerical	ADJ
ijassa-998	257	5	results	result	NOUN
ijassa-998	257	6	using	use	VERB
ijassa-998	257	7	the	the	DET
ijassa-998	257	8	software	software	NOUN
ijassa-998	257	9	tool	tool	NOUN
ijassa-998	257	10	bocop	bocop	NOUN
ijassa-998	257	11	are	be	AUX
ijassa-998	257	12	presented	present	VERB
ijassa-998	257	13	.	.	PUNCT
ijassa-998	258	1	the	the	DET
ijassa-998	258	2	numerical	numerical	ADJ
ijassa-998	258	3	results	result	NOUN
ijassa-998	258	4	show	show	VERB
ijassa-998	258	5	the	the	DET
ijassa-998	258	6	development	development	NOUN
ijassa-998	258	7	of	of	ADP
ijassa-998	258	8	healthy	healthy	ADJ
ijassa-998	258	9	cells	cell	NOUN
ijassa-998	258	10	,	,	PUNCT
ijassa-998	258	11	cancer	cancer	NOUN
ijassa-998	258	12	cells	cell	NOUN
ijassa-998	258	13	and	and	CCONJ
ijassa-998	258	14	the	the	DET
ijassa-998	258	15	optimal	optimal	ADJ
ijassa-998	258	16	control	control	NOUN
ijassa-998	258	17	.	.	PUNCT
ijassa-998	259	1	0	0	NUM
ijassa-998	259	2	50	50	NUM
ijassa-998	259	3	100	100	NUM
ijassa-998	259	4	150	150	NUM
ijassa-998	259	5	non	non	ADJ
ijassa-998	259	6	-	-	ADJ
ijassa-998	259	7	dimensional	dimensional	ADJ
ijassa-998	259	8	time	time	NOUN
ijassa-998	259	9	40	40	NUM
ijassa-998	259	10	42	42	NUM
ijassa-998	259	11	44	44	NUM
ijassa-998	259	12	46	46	NUM
ijassa-998	259	13	48	48	NUM
ijassa-998	259	14	50	50	NUM
ijassa-998	259	15	52	52	NUM
ijassa-998	259	16	54	54	NUM
ijassa-998	259	17	56	56	NUM
ijassa-998	259	18	58	58	NUM
ijassa-998	259	19	60	60	NUM
ijassa-998	259	20	fig	fig	NOUN
ijassa-998	259	21	.	.	PUNCT
ijassa-998	260	1	5.14	5.14	NUM
ijassa-998	260	2	.	.	PUNCT
ijassa-998	260	3	time	time	NOUN
ijassa-998	260	4	response	response	NOUN
ijassa-998	260	5	of	of	ADP
ijassa-998	260	6	healthy	healthy	ADJ
ijassa-998	260	7	cells	cell	NOUN
ijassa-998	260	8	e(t	e(t	NOUN
ijassa-998	260	9	)	)	PUNCT
ijassa-998	261	1	using	use	VERB
ijassa-998	261	2	the	the	DET
ijassa-998	261	3	optimal	optimal	ADJ
ijassa-998	261	4	therapy	therapy	NOUN
ijassa-998	261	5	strategy	strategy	NOUN
ijassa-998	261	6	healthy	healthy	ADJ
ijassa-998	261	7	and	and	CCONJ
ijassa-998	261	8	cancer	cancer	NOUN
ijassa-998	261	9	cells	cell	NOUN
ijassa-998	261	10	decrease	decrease	NOUN
ijassa-998	261	11	(	(	PUNCT
ijassa-998	261	12	fig	fig	NOUN
ijassa-998	261	13	.	.	PUNCT
ijassa-998	262	1	5.14	5.14	NUM
ijassa-998	262	2	)	)	PUNCT
ijassa-998	262	3	,	,	PUNCT
ijassa-998	262	4	(	(	PUNCT
ijassa-998	262	5	fig	fig	NOUN
ijassa-998	262	6	.	.	PUNCT
ijassa-998	263	1	5.15	5.15	NUM
ijassa-998	263	2	)	)	PUNCT
ijassa-998	263	3	.	.	PUNCT
ijassa-998	264	1	healthy	healthy	ADJ
ijassa-998	264	2	cellse(t	cellse(t	PROPN
ijassa-998	264	3	)	)	PUNCT
ijassa-998	264	4	then	then	ADV
ijassa-998	264	5	progress	progress	VERB
ijassa-998	264	6	along	along	ADP
ijassa-998	264	7	the	the	DET
ijassa-998	264	8	boundary	boundary	NOUN
ijassa-998	264	9	.	.	PUNCT
ijassa-998	265	1	after	after	ADP
ijassa-998	265	2	a	a	DET
ijassa-998	265	3	period	period	NOUN
ijassa-998	265	4	where	where	SCONJ
ijassa-998	265	5	the	the	DET
ijassa-998	265	6	maximal	maximal	ADJ
ijassa-998	265	7	amount	amount	NOUN
ijassa-998	265	8	of	of	ADP
ijassa-998	265	9	drug	drug	NOUN
ijassa-998	265	10	is	be	AUX
ijassa-998	265	11	administered	administer	VERB
ijassa-998	265	12	follows	follow	VERB
ijassa-998	265	13	a	a	DET
ijassa-998	265	14	short	short	ADJ
ijassa-998	265	15	relaxation	relaxation	NOUN
ijassa-998	265	16	phase	phase	NOUN
ijassa-998	265	17	.	.	PUNCT
ijassa-998	266	1	then	then	ADV
ijassa-998	266	2	the	the	DET
ijassa-998	266	3	maximal	maximal	ADJ
ijassa-998	266	4	admissible	admissible	ADJ
ijassa-998	266	5	amount	amount	NOUN
ijassa-998	266	6	of	of	ADP
ijassa-998	266	7	medicine	medicine	NOUN
ijassa-998	266	8	which	which	PRON
ijassa-998	266	9	minimizes	minimize	VERB
ijassa-998	266	10	the	the	DET
ijassa-998	266	11	objective	objective	ADJ
ijassa-998	266	12	function	function	NOUN
ijassa-998	266	13	is	be	AUX
ijassa-998	266	14	applied	apply	VERB
ijassa-998	266	15	.	.	PUNCT
ijassa-998	267	1	the	the	DET
ijassa-998	267	2	following	follow	VERB
ijassa-998	267	3	table	table	NOUN
ijassa-998	267	4	presents	present	VERB
ijassa-998	267	5	the	the	DET
ijassa-998	267	6	values	value	NOUN
ijassa-998	267	7	of	of	ADP
ijassa-998	267	8	the	the	DET
ijassa-998	267	9	objective	objective	ADJ
ijassa-998	267	10	function	function	NOUN
ijassa-998	267	11	,	,	PUNCT
ijassa-998	267	12	the	the	DET
ijassa-998	267	13	healthy	healthy	ADJ
ijassa-998	267	14	cells	cell	NOUN
ijassa-998	267	15	and	and	CCONJ
ijassa-998	267	16	cancer	cancer	NOUN
ijassa-998	267	17	cells	cell	NOUN
ijassa-998	267	18	at	at	ADP
ijassa-998	267	19	the	the	DET
ijassa-998	267	20	end	end	NOUN
ijassa-998	267	21	of	of	ADP
ijassa-998	267	22	the	the	DET
ijassa-998	267	23	therapy	therapy	NOUN
ijassa-998	267	24	process	process	NOUN
ijassa-998	267	25	(	(	PUNCT
ijassa-998	267	26	t	t	NOUN
ijassa-998	267	27	=	=	SYM
ijassa-998	267	28	150	150	NUM
ijassa-998	267	29	)	)	PUNCT
ijassa-998	267	30	.	.	PUNCT
ijassa-998	268	1	note	note	VERB
ijassa-998	268	2	that	that	SCONJ
ijassa-998	268	3	in	in	ADP
ijassa-998	268	4	the	the	DET
ijassa-998	268	5	results	result	NOUN
ijassa-998	268	6	achieved	achieve	VERB
ijassa-998	268	7	by	by	ADP
ijassa-998	268	8	the	the	DET
ijassa-998	268	9	alternative	alternative	ADJ
ijassa-998	268	10	therapy	therapy	NOUN
ijassa-998	268	11	strategy	strategy	NOUN
ijassa-998	268	12	the	the	DET
ijassa-998	268	13	modification	modification	NOUN
ijassa-998	268	14	(	(	PUNCT
ijassa-998	268	15	3.11	3.11	NUM
ijassa-998	268	16	)	)	PUNCT
ijassa-998	268	17	is	be	AUX
ijassa-998	268	18	used	use	VERB
ijassa-998	268	19	.	.	PUNCT
ijassa-998	269	1	therefore	therefore	ADV
ijassa-998	269	2	the	the	DET
ijassa-998	269	3	results	result	NOUN
ijassa-998	269	4	of	of	ADP
ijassa-998	269	5	the	the	DET
ijassa-998	269	6	alternative	alternative	ADJ
ijassa-998	269	7	strategy	strategy	NOUN
ijassa-998	269	8	are	be	AUX
ijassa-998	269	9	better	well	ADJ
ijassa-998	269	10	than	than	ADP
ijassa-998	269	11	the	the	DET
ijassa-998	269	12	ones	one	NOUN
ijassa-998	269	13	obtained	obtain	VERB
ijassa-998	269	14	with	with	ADP
ijassa-998	269	15	the	the	DET
ijassa-998	269	16	suboptimal	suboptimal	ADJ
ijassa-998	269	17	one	one	NOUN
ijassa-998	269	18	.	.	PUNCT
ijassa-998	270	1	copyright	copyright	NOUN
ijassa-998	270	2	c	c	ADP
ijassa-998	270	3	©	©	PROPN
ijassa-998	270	4	2020	2020	NUM
ijassa-998	270	5	assa	assa	NOUN
ijassa-998	270	6	.	.	PUNCT
ijassa-998	271	1	adv	adv	PROPN
ijassa-998	271	2	syst	syst	PROPN
ijassa-998	271	3	sci	sci	PROPN
ijassa-998	271	4	appl	appl	PROPN
ijassa-998	271	5	(	(	PUNCT
ijassa-998	271	6	2020	2020	NUM
ijassa-998	271	7	)	)	PUNCT
ijassa-998	271	8	98	98	NUM
ijassa-998	271	9	m.-c	m.-c	NOUN
ijassa-998	271	10	.	.	PUNCT
ijassa-998	272	1	litzinger	litzinger	NOUN
ijassa-998	272	2	,	,	PUNCT
ijassa-998	272	3	y.	y.	PROPN
ijassa-998	272	4	todorov	todorov	PROPN
ijassa-998	272	5	,	,	PUNCT
ijassa-998	272	6	m.	m.	NOUN
ijassa-998	272	7	föller	föller	PROPN
ijassa-998	272	8	-	-	PUNCT
ijassa-998	272	9	nord	nord	PROPN
ijassa-998	272	10	,	,	PUNCT
ijassa-998	272	11	m.k	m.k	PROPN
ijassa-998	272	12	.	.	PUNCT
ijassa-998	272	13	chaudhary	chaudhary	PROPN
ijassa-998	272	14	,	,	PUNCT
ijassa-998	272	15	a.s	a.s	PROPN
ijassa-998	272	16	.	.	PROPN
ijassa-998	272	17	bratus	bratus	PROPN
ijassa-998	272	18	0	0	NUM
ijassa-998	272	19	50	50	NUM
ijassa-998	272	20	100	100	NUM
ijassa-998	272	21	150	150	NUM
ijassa-998	272	22	non	non	ADJ
ijassa-998	272	23	-	-	ADJ
ijassa-998	272	24	dimensional	dimensional	ADJ
ijassa-998	272	25	time	time	NOUN
ijassa-998	272	26	100	100	NUM
ijassa-998	272	27	110	110	NUM
ijassa-998	272	28	120	120	NUM
ijassa-998	272	29	130	130	NUM
ijassa-998	272	30	140	140	NUM
ijassa-998	272	31	150	150	NUM
ijassa-998	272	32	160	160	NUM
ijassa-998	272	33	fig	fig	NOUN
ijassa-998	272	34	.	.	PUNCT
ijassa-998	273	1	5.15	5.15	NUM
ijassa-998	273	2	.	.	PUNCT
ijassa-998	273	3	time	time	NOUN
ijassa-998	273	4	response	response	NOUN
ijassa-998	273	5	of	of	ADP
ijassa-998	273	6	the	the	DET
ijassa-998	273	7	cancer	cancer	NOUN
ijassa-998	273	8	cells	cell	NOUN
ijassa-998	273	9	z(t	z(t	NOUN
ijassa-998	273	10	)	)	PUNCT
ijassa-998	274	1	using	use	VERB
ijassa-998	274	2	the	the	DET
ijassa-998	274	3	optimal	optimal	ADJ
ijassa-998	274	4	therapy	therapy	NOUN
ijassa-998	274	5	strategy	strategy	NOUN
ijassa-998	274	6	0	0	NUM
ijassa-998	274	7	50	50	NUM
ijassa-998	274	8	100	100	NUM
ijassa-998	274	9	150	150	NUM
ijassa-998	274	10	non	non	ADJ
ijassa-998	274	11	-	-	ADJ
ijassa-998	274	12	dimensional	dimensional	ADJ
ijassa-998	274	13	time	time	NOUN
ijassa-998	274	14	0	0	NUM
ijassa-998	274	15	0.5	0.5	NUM
ijassa-998	274	16	1	1	NUM
ijassa-998	274	17	1.5	1.5	NUM
ijassa-998	274	18	2	2	NUM
ijassa-998	274	19	2.5	2.5	NUM
ijassa-998	274	20	3	3	NUM
ijassa-998	274	21	3.5	3.5	NUM
ijassa-998	274	22	4	4	NUM
ijassa-998	274	23	4.5	4.5	NUM
ijassa-998	274	24	5	5	NUM
ijassa-998	274	25	fig	fig	NOUN
ijassa-998	274	26	.	.	PUNCT
ijassa-998	275	1	5.16	5.16	NUM
ijassa-998	275	2	.	.	PUNCT
ijassa-998	275	3	amount	amount	NOUN
ijassa-998	275	4	of	of	ADP
ijassa-998	275	5	the	the	DET
ijassa-998	275	6	administered	administer	VERB
ijassa-998	275	7	drug	drug	NOUN
ijassa-998	275	8	u(t	u(t	NOUN
ijassa-998	275	9	)	)	PUNCT
ijassa-998	275	10	using	use	VERB
ijassa-998	275	11	the	the	DET
ijassa-998	275	12	optimal	optimal	ADJ
ijassa-998	275	13	therapy	therapy	NOUN
ijassa-998	275	14	strategy	strategy	NOUN
ijassa-998	275	15	6	6	NUM
ijassa-998	275	16	.	.	PUNCT
ijassa-998	275	17	summary	summary	VERB
ijassa-998	275	18	a	a	DET
ijassa-998	275	19	simplified	simplified	ADJ
ijassa-998	275	20	mathematical	mathematical	ADJ
ijassa-998	275	21	model	model	NOUN
ijassa-998	275	22	for	for	ADP
ijassa-998	275	23	the	the	DET
ijassa-998	275	24	therapy	therapy	NOUN
ijassa-998	275	25	of	of	ADP
ijassa-998	275	26	prostate	prostate	NOUN
ijassa-998	275	27	cancer	cancer	NOUN
ijassa-998	275	28	regarding	regard	VERB
ijassa-998	275	29	androgen	androgen	NOUN
ijassa-998	275	30	ablation	ablation	NOUN
ijassa-998	275	31	is	be	AUX
ijassa-998	275	32	considered	consider	VERB
ijassa-998	275	33	.	.	PUNCT
ijassa-998	276	1	the	the	DET
ijassa-998	276	2	effect	effect	NOUN
ijassa-998	276	3	of	of	ADP
ijassa-998	276	4	the	the	DET
ijassa-998	276	5	therapy	therapy	NOUN
ijassa-998	276	6	on	on	ADP
ijassa-998	276	7	cancer	cancer	NOUN
ijassa-998	276	8	and	and	CCONJ
ijassa-998	276	9	healthy	healthy	ADJ
ijassa-998	276	10	cells	cell	NOUN
ijassa-998	276	11	is	be	AUX
ijassa-998	276	12	assumed	assume	VERB
ijassa-998	276	13	to	to	ADP
ijassa-998	276	14	copyright	copyright	NOUN
ijassa-998	276	15	c	c	ADP
ijassa-998	276	16	©	©	PROPN
ijassa-998	276	17	2020	2020	NUM
ijassa-998	276	18	assa	assa	NOUN
ijassa-998	276	19	.	.	PUNCT
ijassa-998	277	1	adv	adv	PROPN
ijassa-998	277	2	syst	syst	PROPN
ijassa-998	277	3	sci	sci	PROPN
ijassa-998	277	4	appl	appl	PROPN
ijassa-998	277	5	(	(	PUNCT
ijassa-998	277	6	2020	2020	NUM
ijassa-998	277	7	)	)	PUNCT
ijassa-998	277	8	on	on	ADP
ijassa-998	277	9	optimal	optimal	ADJ
ijassa-998	277	10	therapy	therapy	NOUN
ijassa-998	277	11	protocols	protocol	NOUN
ijassa-998	277	12	in	in	ADP
ijassa-998	277	13	the	the	DET
ijassa-998	277	14	math	math	NOUN
ijassa-998	277	15	.	.	PUNCT
ijassa-998	278	1	model	model	NOUN
ijassa-998	278	2	of	of	ADP
ijassa-998	278	3	prostate	prostate	NOUN
ijassa-998	278	4	cancer	cancer	NOUN
ijassa-998	278	5	progression	progression	NOUN
ijassa-998	278	6	99	99	NUM
ijassa-998	278	7	therapy	therapy	NOUN
ijassa-998	278	8	strategy	strategy	NOUN
ijassa-998	278	9	j(t	j(t	PROPN
ijassa-998	278	10	)	)	PUNCT
ijassa-998	279	1	e(t	e(t	PROPN
ijassa-998	279	2	)	)	PUNCT
ijassa-998	280	1	z(t	z(t	NOUN
ijassa-998	280	2	)	)	PUNCT
ijassa-998	280	3	alternative	alternative	NOUN
ijassa-998	280	4	therapy	therapy	NOUN
ijassa-998	280	5	strategy	strategy	NOUN
ijassa-998	280	6	1.988	1.988	NUM
ijassa-998	280	7	·	·	SYM
ijassa-998	280	8	104	104	NUM
ijassa-998	280	9	46.222	46.222	NUM
ijassa-998	280	10	117.88	117.88	NUM
ijassa-998	280	11	suboptimal	suboptimal	ADJ
ijassa-998	280	12	therapy	therapy	NOUN
ijassa-998	280	13	strategy	strategy	NOUN
ijassa-998	280	14	2.029	2.029	NUM
ijassa-998	280	15	·	·	PUNCT
ijassa-998	281	1	104	104	NUM
ijassa-998	281	2	47.414	47.414	NUM
ijassa-998	281	3	123.14	123.14	NUM
ijassa-998	281	4	optimal	optimal	ADJ
ijassa-998	281	5	therapy	therapy	NOUN
ijassa-998	281	6	strategy	strategy	NOUN
ijassa-998	281	7	1.195	1.195	NUM
ijassa-998	281	8	·	·	SYM
ijassa-998	281	9	104	104	NUM
ijassa-998	281	10	46.000	46.000	NUM
ijassa-998	281	11	114.98	114.98	NUM
ijassa-998	281	12	table	table	NOUN
ijassa-998	281	13	5.1	5.1	NUM
ijassa-998	281	14	.	.	PUNCT
ijassa-998	282	1	comparison	comparison	NOUN
ijassa-998	282	2	of	of	ADP
ijassa-998	282	3	the	the	DET
ijassa-998	282	4	terminal	terminal	ADJ
ijassa-998	282	5	values	value	NOUN
ijassa-998	282	6	of	of	ADP
ijassa-998	282	7	the	the	DET
ijassa-998	282	8	three	three	NUM
ijassa-998	282	9	considered	consider	VERB
ijassa-998	282	10	approaches	approach	NOUN
ijassa-998	282	11	reduce	reduce	VERB
ijassa-998	282	12	the	the	DET
ijassa-998	282	13	birth	birth	NOUN
ijassa-998	282	14	rate	rate	NOUN
ijassa-998	282	15	of	of	ADP
ijassa-998	282	16	the	the	DET
ijassa-998	282	17	populations	population	NOUN
ijassa-998	282	18	of	of	ADP
ijassa-998	282	19	the	the	DET
ijassa-998	282	20	considered	consider	VERB
ijassa-998	282	21	cell	cell	NOUN
ijassa-998	282	22	types	type	NOUN
ijassa-998	282	23	.	.	PUNCT
ijassa-998	283	1	an	an	DET
ijassa-998	283	2	optimization	optimization	NOUN
ijassa-998	283	3	problem	problem	NOUN
ijassa-998	283	4	with	with	ADP
ijassa-998	283	5	a	a	DET
ijassa-998	283	6	constraint	constraint	NOUN
ijassa-998	283	7	on	on	ADP
ijassa-998	283	8	the	the	DET
ijassa-998	283	9	amount	amount	NOUN
ijassa-998	283	10	of	of	ADP
ijassa-998	283	11	healthy	healthy	ADJ
ijassa-998	283	12	cells	cell	NOUN
ijassa-998	283	13	during	during	ADP
ijassa-998	283	14	the	the	DET
ijassa-998	283	15	therapy	therapy	NOUN
ijassa-998	283	16	process	process	NOUN
ijassa-998	283	17	is	be	AUX
ijassa-998	283	18	introduced	introduce	VERB
ijassa-998	283	19	.	.	PUNCT
ijassa-998	284	1	three	three	NUM
ijassa-998	284	2	therapy	therapy	NOUN
ijassa-998	284	3	strategy	strategy	NOUN
ijassa-998	284	4	approaches	approach	NOUN
ijassa-998	284	5	of	of	ADP
ijassa-998	284	6	the	the	DET
ijassa-998	284	7	problem	problem	NOUN
ijassa-998	284	8	are	be	AUX
ijassa-998	284	9	illustrated	illustrate	VERB
ijassa-998	284	10	and	and	CCONJ
ijassa-998	284	11	solved	solve	VERB
ijassa-998	284	12	by	by	ADP
ijassa-998	284	13	combinating	combinate	VERB
ijassa-998	284	14	analytical	analytical	ADJ
ijassa-998	284	15	and	and	CCONJ
ijassa-998	284	16	numerical	numerical	ADJ
ijassa-998	284	17	procedures	procedure	NOUN
ijassa-998	284	18	.	.	PUNCT
ijassa-998	285	1	the	the	DET
ijassa-998	285	2	presented	present	VERB
ijassa-998	285	3	results	result	NOUN
ijassa-998	285	4	of	of	ADP
ijassa-998	285	5	the	the	DET
ijassa-998	285	6	therapy	therapy	NOUN
ijassa-998	285	7	strategies	strategy	NOUN
ijassa-998	285	8	using	use	VERB
ijassa-998	285	9	the	the	DET
ijassa-998	285	10	suboptimal	suboptimal	ADJ
ijassa-998	285	11	and	and	CCONJ
ijassa-998	285	12	alternative	alternative	ADJ
ijassa-998	285	13	control	control	NOUN
ijassa-998	285	14	demonstrate	demonstrate	VERB
ijassa-998	285	15	that	that	SCONJ
ijassa-998	285	16	the	the	DET
ijassa-998	285	17	mathematical	mathematical	ADJ
ijassa-998	285	18	challenges	challenge	NOUN
ijassa-998	285	19	of	of	ADP
ijassa-998	285	20	the	the	DET
ijassa-998	285	21	classical	classical	ADJ
ijassa-998	285	22	optimal	optimal	ADJ
ijassa-998	285	23	control	control	NOUN
ijassa-998	285	24	problem	problem	NOUN
ijassa-998	285	25	with	with	ADP
ijassa-998	285	26	state	state	NOUN
ijassa-998	285	27	constraints	constraint	NOUN
ijassa-998	285	28	can	can	AUX
ijassa-998	285	29	be	be	AUX
ijassa-998	285	30	circumvented	circumvent	VERB
ijassa-998	285	31	and	and	CCONJ
ijassa-998	285	32	the	the	DET
ijassa-998	285	33	approaches	approach	NOUN
ijassa-998	285	34	can	can	AUX
ijassa-998	285	35	be	be	AUX
ijassa-998	285	36	used	use	VERB
ijassa-998	285	37	for	for	ADP
ijassa-998	285	38	medicine	medicine	NOUN
ijassa-998	285	39	.	.	PUNCT
ijassa-998	286	1	moreover	moreover	ADV
ijassa-998	286	2	the	the	DET
ijassa-998	286	3	suggested	suggest	VERB
ijassa-998	286	4	mathematical	mathematical	ADJ
ijassa-998	286	5	model	model	NOUN
ijassa-998	286	6	produces	produce	VERB
ijassa-998	286	7	possibilities	possibility	NOUN
ijassa-998	286	8	for	for	ADP
ijassa-998	286	9	further	further	ADJ
ijassa-998	286	10	investigations	investigation	NOUN
ijassa-998	286	11	regarding	regard	VERB
ijassa-998	286	12	the	the	DET
ijassa-998	286	13	physical	physical	ADJ
ijassa-998	286	14	condition	condition	NOUN
ijassa-998	286	15	of	of	ADP
ijassa-998	286	16	a	a	DET
ijassa-998	286	17	patient	patient	NOUN
ijassa-998	286	18	which	which	PRON
ijassa-998	286	19	can	can	AUX
ijassa-998	286	20	be	be	AUX
ijassa-998	286	21	modelled	model	VERB
ijassa-998	286	22	by	by	ADP
ijassa-998	286	23	means	mean	NOUN
ijassa-998	286	24	of	of	ADP
ijassa-998	286	25	different	different	ADJ
ijassa-998	286	26	parameters	parameter	NOUN
ijassa-998	286	27	of	of	ADP
ijassa-998	286	28	the	the	DET
ijassa-998	286	29	model	model	NOUN
ijassa-998	286	30	.	.	PUNCT
ijassa-998	287	1	from	from	ADP
ijassa-998	287	2	the	the	DET
ijassa-998	287	3	mathematical	mathematical	ADJ
ijassa-998	287	4	point	point	NOUN
ijassa-998	287	5	of	of	ADP
ijassa-998	287	6	view	view	NOUN
ijassa-998	287	7	the	the	DET
ijassa-998	287	8	considered	consider	VERB
ijassa-998	287	9	problem	problem	NOUN
ijassa-998	287	10	covers	cover	VERB
ijassa-998	287	11	theoretical	theoretical	ADJ
ijassa-998	287	12	investigations	investigation	NOUN
ijassa-998	287	13	on	on	ADP
ijassa-998	287	14	the	the	DET
ijassa-998	287	15	necessary	necessary	ADJ
ijassa-998	287	16	and	and	CCONJ
ijassa-998	287	17	sufficient	sufficient	ADJ
ijassa-998	287	18	conditions	condition	NOUN
ijassa-998	287	19	of	of	ADP
ijassa-998	287	20	optimal	optimal	ADJ
ijassa-998	287	21	control	control	NOUN
ijassa-998	287	22	problems	problem	NOUN
ijassa-998	287	23	with	with	ADP
ijassa-998	287	24	state	state	NOUN
ijassa-998	287	25	constraints	constraint	NOUN
ijassa-998	287	26	.	.	PUNCT
ijassa-998	288	1	acknowledgements	acknowledgement	NOUN
ijassa-998	288	2	this	this	DET
ijassa-998	288	3	research	research	NOUN
ijassa-998	288	4	is	be	AUX
ijassa-998	288	5	supported	support	VERB
ijassa-998	288	6	by	by	ADP
ijassa-998	288	7	the	the	DET
ijassa-998	288	8	russian	russian	ADJ
ijassa-998	288	9	scientific	scientific	ADJ
ijassa-998	288	10	foundation	foundation	NOUN
ijassa-998	288	11	grant	grant	VERB
ijassa-998	288	12	19	19	NUM
ijassa-998	288	13	-	-	PUNCT
ijassa-998	288	14	11	11	NUM
ijassa-998	288	15	-	-	PUNCT
ijassa-998	288	16	00008	00008	NUM
ijassa-998	288	17	and	and	CCONJ
ijassa-998	288	18	grant	grant	VERB
ijassa-998	288	19	rfbi	rfbi	NOUN
ijassa-998	288	20	20	20	NUM
ijassa-998	288	21	-	-	PUNCT
ijassa-998	288	22	04	04	NUM
ijassa-998	288	23	-	-	PUNCT
ijassa-998	288	24	60157	60157	NUM
ijassa-998	288	25	and	and	CCONJ
ijassa-998	288	26	ministry	ministry	PROPN
ijassa-998	288	27	of	of	ADP
ijassa-998	288	28	science	science	NOUN
ijassa-998	288	29	of	of	ADP
ijassa-998	288	30	higher	high	ADJ
ijassa-998	288	31	education	education	NOUN
ijassa-998	288	32	grant	grant	NOUN
ijassa-998	288	33	075	075	NUM
ijassa-998	288	34	-	-	PUNCT
ijassa-998	288	35	15	15	NUM
ijassa-998	288	36	-	-	SYM
ijassa-998	288	37	20191621	20191621	NUM
ijassa-998	288	38	.	.	PUNCT
ijassa-998	289	1	references	reference	NOUN
ijassa-998	289	2	1	1	NUM
ijassa-998	289	3	.	.	PUNCT
ijassa-998	290	1	agus	agus	PROPN
ijassa-998	290	2	,	,	PUNCT
ijassa-998	290	3	d.b	d.b	PROPN
ijassa-998	290	4	.	.	PROPN
ijassa-998	290	5	,	,	PUNCT
ijassa-998	290	6	et	et	PROPN
ijassa-998	290	7	al	al	PROPN
ijassa-998	290	8	.	.	PROPN
ijassa-998	290	9	(	(	PUNCT
ijassa-998	290	10	1990	1990	NUM
ijassa-998	290	11	)	)	PUNCT
ijassa-998	290	12	,	,	PUNCT
ijassa-998	290	13	prostate	prostate	NOUN
ijassa-998	290	14	cancer	cancer	NOUN
ijassa-998	290	15	cell	cell	NOUN
ijassa-998	290	16	cycle	cycle	NOUN
ijassa-998	290	17	regulators	regulator	NOUN
ijassa-998	290	18	:	:	PUNCT
ijassa-998	290	19	response	response	NOUN
ijassa-998	290	20	to	to	ADP
ijassa-998	290	21	androgen	androgen	NOUN
ijassa-998	290	22	withdrawal	withdrawal	NOUN
ijassa-998	290	23	and	and	CCONJ
ijassa-998	290	24	development	development	NOUN
ijassa-998	290	25	of	of	ADP
ijassa-998	290	26	androgen	androgen	NOUN
ijassa-998	290	27	independence	independence	NOUN
ijassa-998	290	28	,	,	PUNCT
ijassa-998	290	29	j	j	PROPN
ijassa-998	290	30	natl	natl	PROPN
ijassa-998	290	31	cancer	cancer	PROPN
ijassa-998	290	32	inst	inst	PROPN
ijassa-998	290	33	,	,	PUNCT
ijassa-998	290	34	91	91	NUM
ijassa-998	290	35	,	,	PUNCT
ijassa-998	290	36	1869	1869	NUM
ijassa-998	290	37	–	–	PUNCT
ijassa-998	290	38	1876	1876	NUM
ijassa-998	290	39	.	.	PUNCT
ijassa-998	291	1	2	2	X
ijassa-998	291	2	.	.	NUM
ijassa-998	291	3	balk	balk	VERB
ijassa-998	291	4	,	,	PUNCT
ijassa-998	291	5	s.p	s.p	PROPN
ijassa-998	291	6	.	.	PUNCT
ijassa-998	291	7	(	(	PUNCT
ijassa-998	291	8	2002	2002	NUM
ijassa-998	291	9	)	)	PUNCT
ijassa-998	291	10	,	,	PUNCT
ijassa-998	291	11	androgen	androgen	NOUN
ijassa-998	291	12	receptor	receptor	NOUN
ijassa-998	291	13	as	as	ADP
ijassa-998	291	14	a	a	DET
ijassa-998	291	15	target	target	NOUN
ijassa-998	291	16	in	in	ADP
ijassa-998	291	17	androgen	androgen	NOUN
ijassa-998	291	18	-	-	PUNCT
ijassa-998	291	19	independent	independent	ADJ
ijassa-998	291	20	prostate	prostate	NOUN
ijassa-998	291	21	cancer	cancer	NOUN
ijassa-998	291	22	,	,	PUNCT
ijassa-998	291	23	urology	urology	NOUN
ijassa-998	291	24	,	,	PUNCT
ijassa-998	291	25	60	60	NUM
ijassa-998	291	26	,	,	PUNCT
ijassa-998	291	27	132–138	132–138	NUM
ijassa-998	291	28	.	.	PUNCT
ijassa-998	292	1	3	3	X
ijassa-998	292	2	.	.	X
ijassa-998	292	3	byrne	byrne	PROPN
ijassa-998	292	4	,	,	PUNCT
ijassa-998	292	5	h.m	h.m	PROPN
ijassa-998	292	6	.	.	PROPN
ijassa-998	292	7	(	(	PUNCT
ijassa-998	292	8	2010	2010	NUM
ijassa-998	292	9	)	)	PUNCT
ijassa-998	292	10	,	,	PUNCT
ijassa-998	292	11	dissecting	dissect	VERB
ijassa-998	292	12	cancer	cancer	NOUN
ijassa-998	292	13	through	through	ADP
ijassa-998	292	14	mathematics	mathematic	NOUN
ijassa-998	292	15	:	:	PUNCT
ijassa-998	292	16	from	from	ADP
ijassa-998	292	17	the	the	DET
ijassa-998	292	18	cell	cell	NOUN
ijassa-998	292	19	to	to	ADP
ijassa-998	292	20	the	the	DET
ijassa-998	292	21	animal	animal	NOUN
ijassa-998	292	22	model	model	NOUN
ijassa-998	292	23	,	,	PUNCT
ijassa-998	292	24	nature	nature	NOUN
ijassa-998	292	25	reviews	review	NOUN
ijassa-998	292	26	cancer	cancer	NOUN
ijassa-998	292	27	,	,	PUNCT
ijassa-998	292	28	10	10	NUM
ijassa-998	292	29	,	,	PUNCT
ijassa-998	292	30	221–230	221–230	NUM
ijassa-998	292	31	.	.	PUNCT
ijassa-998	293	1	4	4	NUM
ijassa-998	293	2	.	.	X
ijassa-998	293	3	bellomo	bellomo	PROPN
ijassa-998	293	4	,	,	PUNCT
ijassa-998	293	5	n.	n.	PROPN
ijassa-998	293	6	&	&	CCONJ
ijassa-998	293	7	preziosi	preziosi	PROPN
ijassa-998	293	8	,	,	PUNCT
ijassa-998	293	9	l.	l.	PROPN
ijassa-998	293	10	(	(	PUNCT
ijassa-998	293	11	2000	2000	NUM
ijassa-998	293	12	)	)	PUNCT
ijassa-998	293	13	,	,	PUNCT
ijassa-998	293	14	modelling	modelling	NOUN
ijassa-998	293	15	and	and	CCONJ
ijassa-998	293	16	mathematical	mathematical	ADJ
ijassa-998	293	17	problems	problem	NOUN
ijassa-998	293	18	related	relate	VERB
ijassa-998	293	19	to	to	ADP
ijassa-998	293	20	tumor	tumor	NOUN
ijassa-998	293	21	evolution	evolution	NOUN
ijassa-998	293	22	and	and	CCONJ
ijassa-998	293	23	its	its	PRON
ijassa-998	293	24	interaction	interaction	NOUN
ijassa-998	293	25	with	with	ADP
ijassa-998	293	26	the	the	DET
ijassa-998	293	27	immune	immune	ADJ
ijassa-998	293	28	system	system	NOUN
ijassa-998	293	29	,	,	PUNCT
ijassa-998	293	30	mathematical	mathematical	ADJ
ijassa-998	293	31	and	and	CCONJ
ijassa-998	293	32	computer	computer	NOUN
ijassa-998	293	33	modelling	modelling	NOUN
ijassa-998	293	34	,	,	PUNCT
ijassa-998	293	35	32	32	NUM
ijassa-998	293	36	,	,	PUNCT
ijassa-998	293	37	413–452	413–452	NUM
ijassa-998	293	38	.	.	PUNCT
ijassa-998	294	1	5	5	X
ijassa-998	294	2	.	.	X
ijassa-998	294	3	donovan	donovan	PROPN
ijassa-998	294	4	,	,	PUNCT
ijassa-998	294	5	k.a	k.a	PROPN
ijassa-998	294	6	.	.	PROPN
ijassa-998	294	7	,	,	PUNCT
ijassa-998	294	8	walker	walker	PROPN
ijassa-998	294	9	,	,	PUNCT
ijassa-998	294	10	l.m	l.m	PROPN
ijassa-998	294	11	.	.	PROPN
ijassa-998	294	12	,	,	PUNCT
ijassa-998	294	13	wassersug	wassersug	NOUN
ijassa-998	294	14	,	,	PUNCT
ijassa-998	294	15	r.j	r.j	PROPN
ijassa-998	294	16	.	.	PROPN
ijassa-998	294	17	,	,	PUNCT
ijassa-998	294	18	thompson	thompson	PROPN
ijassa-998	294	19	,	,	PUNCT
ijassa-998	294	20	l.m	l.m	PROPN
ijassa-998	294	21	.	.	PROPN
ijassa-998	294	22	&	&	CCONJ
ijassa-998	294	23	robinson	robinson	PROPN
ijassa-998	294	24	,	,	PUNCT
ijassa-998	294	25	j.w	j.w	PROPN
ijassa-998	294	26	.	.	PROPN
ijassa-998	295	1	(	(	PUNCT
ijassa-998	295	2	2015	2015	NUM
ijassa-998	295	3	)	)	PUNCT
ijassa-998	295	4	,	,	PUNCT
ijassa-998	295	5	psychological	psychological	ADJ
ijassa-998	295	6	effects	effect	NOUN
ijassa-998	295	7	of	of	ADP
ijassa-998	295	8	androgen	androgen	NOUN
ijassa-998	295	9	-	-	PUNCT
ijassa-998	295	10	deprivation	deprivation	NOUN
ijassa-998	295	11	therapy	therapy	NOUN
ijassa-998	295	12	on	on	ADP
ijassa-998	295	13	men	man	NOUN
ijassa-998	295	14	with	with	ADP
ijassa-998	295	15	prostate	prostate	NOUN
ijassa-998	295	16	cancer	cancer	NOUN
ijassa-998	295	17	and	and	CCONJ
ijassa-998	295	18	their	their	PRON
ijassa-998	295	19	partners	partner	NOUN
ijassa-998	295	20	,	,	PUNCT
ijassa-998	295	21	cancer	cancer	NOUN
ijassa-998	295	22	,	,	PUNCT
ijassa-998	295	23	121	121	NUM
ijassa-998	295	24	,	,	PUNCT
ijassa-998	295	25	4286–4299	4286–4299	NUM
ijassa-998	295	26	.	.	PROPN
ijassa-998	296	1	6	6	X
ijassa-998	296	2	.	.	X
ijassa-998	296	3	gatenby	gatenby	PROPN
ijassa-998	296	4	,	,	PUNCT
ijassa-998	296	5	r.a	r.a	PROPN
ijassa-998	296	6	.	.	PROPN
ijassa-998	296	7	and	and	CCONJ
ijassa-998	296	8	maini	maini	PROPN
ijassa-998	296	9	,	,	PUNCT
ijassa-998	296	10	p.k	p.k	PROPN
ijassa-998	296	11	.	.	PUNCT
ijassa-998	296	12	(	(	PUNCT
ijassa-998	296	13	2003	2003	NUM
ijassa-998	296	14	)	)	PUNCT
ijassa-998	296	15	,	,	PUNCT
ijassa-998	296	16	mathematical	mathematical	ADJ
ijassa-998	296	17	oncology	oncology	NOUN
ijassa-998	296	18	:	:	PUNCT
ijassa-998	296	19	cancer	cancer	NOUN
ijassa-998	296	20	summed	sum	VERB
ijassa-998	296	21	up	up	ADP
ijassa-998	296	22	,	,	PUNCT
ijassa-998	296	23	nature	nature	NOUN
ijassa-998	296	24	,	,	PUNCT
ijassa-998	296	25	421	421	NUM
ijassa-998	296	26	,	,	PUNCT
ijassa-998	296	27	page	page	NOUN
ijassa-998	296	28	321	321	NUM
ijassa-998	296	29	.	.	PUNCT
ijassa-998	297	1	7	7	X
ijassa-998	297	2	.	.	X
ijassa-998	297	3	gann	gann	PROPN
ijassa-998	297	4	,	,	PUNCT
ijassa-998	297	5	p.h	p.h	PROPN
ijassa-998	297	6	.	.	PROPN
ijassa-998	297	7	,	,	PUNCT
ijassa-998	297	8	hennekens	hennekens	PROPN
ijassa-998	298	1	c.h	c.h	PROPN
ijassa-998	298	2	.	.	PROPN
ijassa-998	298	3	,	,	PUNCT
ijassa-998	298	4	ma	ma	PROPN
ijassa-998	298	5	j.	j.	PROPN
ijassa-998	298	6	,	,	PUNCT
ijassa-998	298	7	longcope	longcope	PROPN
ijassa-998	298	8	,	,	PUNCT
ijassa-998	298	9	c.	c.	NOUN
ijassa-998	298	10	,	,	PUNCT
ijassa-998	298	11	stampfer	stampfer	NOUN
ijassa-998	298	12	,	,	PUNCT
ijassa-998	298	13	m.j	m.j	PROPN
ijassa-998	298	14	.	.	PROPN
ijassa-998	298	15	(	(	PUNCT
ijassa-998	298	16	1996	1996	NUM
ijassa-998	298	17	)	)	PUNCT
ijassa-998	298	18	,	,	PUNCT
ijassa-998	298	19	prospective	prospective	ADJ
ijassa-998	298	20	study	study	NOUN
ijassa-998	298	21	of	of	ADP
ijassa-998	298	22	sex	sex	NOUN
ijassa-998	298	23	hormone	hormone	NOUN
ijassa-998	298	24	levels	level	NOUN
ijassa-998	298	25	and	and	CCONJ
ijassa-998	298	26	risk	risk	NOUN
ijassa-998	298	27	of	of	ADP
ijassa-998	298	28	prostate	prostate	NOUN
ijassa-998	298	29	cancer	cancer	NOUN
ijassa-998	298	30	,	,	PUNCT
ijassa-998	298	31	j	j	PROPN
ijassa-998	298	32	natl	natl	PROPN
ijassa-998	298	33	cancer	cancer	PROPN
ijassa-998	298	34	inst	inst	PROPN
ijassa-998	298	35	,	,	PUNCT
ijassa-998	298	36	88	88	NUM
ijassa-998	298	37	,	,	PUNCT
ijassa-998	298	38	1118	1118	NUM
ijassa-998	298	39	–	–	PUNCT
ijassa-998	298	40	1126	1126	NUM
ijassa-998	298	41	.	.	PUNCT
ijassa-998	299	1	8	8	X
ijassa-998	299	2	.	.	X
ijassa-998	300	1	heinlein	heinlein	PROPN
ijassa-998	300	2	,	,	PUNCT
ijassa-998	300	3	c.a	c.a	PROPN
ijassa-998	300	4	.	.	PROPN
ijassa-998	300	5	,	,	PUNCT
ijassa-998	300	6	chang	chang	PROPN
ijassa-998	300	7	,	,	PUNCT
ijassa-998	300	8	c.	c.	PROPN
ijassa-998	300	9	(	(	PUNCT
ijassa-998	300	10	2004	2004	NUM
ijassa-998	300	11	)	)	PUNCT
ijassa-998	300	12	,	,	PUNCT
ijassa-998	300	13	androgen	androgen	NOUN
ijassa-998	300	14	receptor	receptor	NOUN
ijassa-998	300	15	in	in	ADP
ijassa-998	300	16	prostate	prostate	NOUN
ijassa-998	300	17	cancer	cancer	NOUN
ijassa-998	300	18	,	,	PUNCT
ijassa-998	300	19	endocr	endocr	PROPN
ijassa-998	300	20	rev	rev	PROPN
ijassa-998	300	21	,	,	PUNCT
ijassa-998	300	22	25	25	NUM
ijassa-998	300	23	,	,	PUNCT
ijassa-998	300	24	276–308	276–308	NUM
ijassa-998	300	25	.	.	PUNCT
ijassa-998	301	1	9	9	NUM
ijassa-998	301	2	.	.	X
ijassa-998	301	3	hirata	hirata	NOUN
ijassa-998	301	4	,	,	PUNCT
ijassa-998	301	5	y.	y.	PROPN
ijassa-998	301	6	,	,	PUNCT
ijassa-998	301	7	tanaka	tanaka	PROPN
ijassa-998	301	8	,	,	PUNCT
ijassa-998	301	9	g.	g.	PROPN
ijassa-998	301	10	,	,	PUNCT
ijassa-998	301	11	bruchovsky	bruchovsky	NOUN
ijassa-998	301	12	,	,	PUNCT
ijassa-998	301	13	n.	n.	NOUN
ijassa-998	301	14	and	and	CCONJ
ijassa-998	301	15	aihara	aihara	PROPN
ijassa-998	301	16	,	,	PUNCT
ijassa-998	301	17	k.	k.	PROPN
ijassa-998	301	18	(	(	PUNCT
ijassa-998	301	19	2012	2012	NUM
ijassa-998	301	20	)	)	PUNCT
ijassa-998	301	21	,	,	PUNCT
ijassa-998	301	22	mathematically	mathematically	ADV
ijassa-998	301	23	modelling	model	VERB
ijassa-998	301	24	and	and	CCONJ
ijassa-998	301	25	controlling	control	VERB
ijassa-998	301	26	prostate	prostate	NOUN
ijassa-998	301	27	cancer	cancer	NOUN
ijassa-998	301	28	under	under	ADP
ijassa-998	301	29	intermittent	intermittent	ADJ
ijassa-998	301	30	hormone	hormone	NOUN
ijassa-998	301	31	therapy	therapy	NOUN
ijassa-998	301	32	,	,	PUNCT
ijassa-998	301	33	asian	asian	ADJ
ijassa-998	301	34	journal	journal	NOUN
ijassa-998	301	35	of	of	ADP
ijassa-998	301	36	copyright	copyright	NOUN
ijassa-998	301	37	c	c	ADP
ijassa-998	301	38	©	©	PROPN
ijassa-998	301	39	2020	2020	NUM
ijassa-998	301	40	assa	assa	NOUN
ijassa-998	301	41	.	.	PUNCT
ijassa-998	302	1	adv	adv	PROPN
ijassa-998	302	2	syst	syst	PROPN
ijassa-998	302	3	sci	sci	PROPN
ijassa-998	302	4	appl	appl	PROPN
ijassa-998	302	5	(	(	PUNCT
ijassa-998	302	6	2020	2020	NUM
ijassa-998	302	7	)	)	PUNCT
ijassa-998	302	8	100	100	NUM
ijassa-998	302	9	m.-c	m.-c	NOUN
ijassa-998	302	10	.	.	PUNCT
ijassa-998	303	1	litzinger	litzinger	NOUN
ijassa-998	303	2	,	,	PUNCT
ijassa-998	303	3	y.	y.	PROPN
ijassa-998	303	4	todorov	todorov	PROPN
ijassa-998	303	5	,	,	PUNCT
ijassa-998	303	6	m.	m.	NOUN
ijassa-998	303	7	föller	föller	PROPN
ijassa-998	303	8	-	-	PUNCT
ijassa-998	303	9	nord	nord	PROPN
ijassa-998	303	10	,	,	PUNCT
ijassa-998	303	11	m.k	m.k	PROPN
ijassa-998	303	12	.	.	PUNCT
ijassa-998	303	13	chaudhary	chaudhary	PROPN
ijassa-998	303	14	,	,	PUNCT
ijassa-998	303	15	a.s	a.s	PROPN
ijassa-998	303	16	.	.	PROPN
ijassa-998	303	17	bratus	bratus	PROPN
ijassa-998	303	18	andrology	andrology	PROPN
ijassa-998	303	19	,	,	PUNCT
ijassa-998	303	20	270–277	270–277	NUM
ijassa-998	303	21	.	.	PUNCT
ijassa-998	304	1	10	10	NUM
ijassa-998	304	2	.	.	X
ijassa-998	305	1	hussain	hussain	PROPN
ijassa-998	305	2	,	,	PUNCT
ijassa-998	305	3	m.	m.	NOUN
ijassa-998	305	4	,	,	PUNCT
ijassa-998	305	5	et	et	PROPN
ijassa-998	305	6	al	al	PROPN
ijassa-998	305	7	.	.	PUNCT
ijassa-998	306	1	(	(	PUNCT
ijassa-998	306	2	2009	2009	NUM
ijassa-998	306	3	)	)	PUNCT
ijassa-998	306	4	,	,	PUNCT
ijassa-998	306	5	prostate	prostate	NOUN
ijassa-998	306	6	-	-	PUNCT
ijassa-998	306	7	specific	specific	ADJ
ijassa-998	306	8	antigen	antigen	NOUN
ijassa-998	306	9	progression	progression	NOUN
ijassa-998	306	10	predicts	predict	VERB
ijassa-998	306	11	overall	overall	ADJ
ijassa-998	306	12	survival	survival	NOUN
ijassa-998	306	13	in	in	ADP
ijassa-998	306	14	patients	patient	NOUN
ijassa-998	306	15	with	with	ADP
ijassa-998	306	16	metastatic	metastatic	ADJ
ijassa-998	306	17	prostate	prostate	NOUN
ijassa-998	306	18	cancer	cancer	NOUN
ijassa-998	306	19	:	:	PUNCT
ijassa-998	306	20	data	datum	NOUN
ijassa-998	306	21	from	from	ADP
ijassa-998	306	22	the	the	DET
ijassa-998	306	23	southwest	southwest	ADJ
ijassa-998	306	24	oncology	oncology	NOUN
ijassa-998	306	25	group	group	NOUN
ijassa-998	306	26	trials	trial	NOUN
ijassa-998	306	27	9346	9346	NUM
ijassa-998	306	28	(	(	PUNCT
ijassa-998	306	29	intergroup	intergroup	NOUN
ijassa-998	306	30	study	study	NOUN
ijassa-998	306	31	0162	0162	NUM
ijassa-998	306	32	)	)	PUNCT
ijassa-998	306	33	and	and	CCONJ
ijassa-998	306	34	9916	9916	NUM
ijassa-998	306	35	,	,	PUNCT
ijassa-998	306	36	j	j	PROPN
ijassa-998	306	37	clin	clin	PROPN
ijassa-998	306	38	oncol	oncol	PROPN
ijassa-998	306	39	,	,	PUNCT
ijassa-998	306	40	27	27	NUM
ijassa-998	306	41	,	,	PUNCT
ijassa-998	306	42	2450–2456	2450–2456	NUM
ijassa-998	306	43	.	.	PUNCT
ijassa-998	307	1	11	11	NUM
ijassa-998	307	2	.	.	X
ijassa-998	307	3	jain	jain	PROPN
ijassa-998	307	4	,	,	PUNCT
ijassa-998	307	5	h.v	h.v	PROPN
ijassa-998	307	6	.	.	PROPN
ijassa-998	307	7	,	,	PUNCT
ijassa-998	307	8	clinton	clinton	PROPN
ijassa-998	307	9	,	,	PUNCT
ijassa-998	307	10	s.k	s.k	PROPN
ijassa-998	307	11	.	.	PROPN
ijassa-998	307	12	,	,	PUNCT
ijassa-998	307	13	bhinder	bhinder	ADJ
ijassa-998	307	14	,	,	PUNCT
ijassa-998	307	15	a.	a.	PROPN
ijassa-998	307	16	&	&	CCONJ
ijassa-998	307	17	friedman	friedman	PROPN
ijassa-998	307	18	,	,	PUNCT
ijassa-998	307	19	a.	a.	NOUN
ijassa-998	307	20	(	(	PUNCT
ijassa-998	307	21	2011	2011	NUM
ijassa-998	307	22	)	)	PUNCT
ijassa-998	307	23	,	,	PUNCT
ijassa-998	307	24	mathematical	mathematical	ADJ
ijassa-998	307	25	modelling	modelling	NOUN
ijassa-998	307	26	of	of	ADP
ijassa-998	307	27	prostate	prostate	NOUN
ijassa-998	307	28	cancer	cancer	NOUN
ijassa-998	307	29	progression	progression	NOUN
ijassa-998	307	30	in	in	ADP
ijassa-998	307	31	response	response	NOUN
ijassa-998	307	32	to	to	ADP
ijassa-998	307	33	androgen	androgen	NOUN
ijassa-998	307	34	ablation	ablation	NOUN
ijassa-998	307	35	therapy	therapy	NOUN
ijassa-998	307	36	,	,	PUNCT
ijassa-998	307	37	proc	proc	PROPN
ijassa-998	307	38	.	.	PUNCT
ijassa-998	308	1	natl	natl	PROPN
ijassa-998	308	2	acad	acad	PROPN
ijassa-998	308	3	.	.	PUNCT
ijassa-998	309	1	sci	sci	PROPN
ijassa-998	309	2	.	.	PROPN
ijassa-998	309	3	usa	usa	PROPN
ijassa-998	309	4	,	,	PUNCT
ijassa-998	309	5	108	108	NUM
ijassa-998	309	6	,	,	PUNCT
ijassa-998	309	7	19701–19706	19701–19706	NUM
ijassa-998	309	8	.	.	NOUN
ijassa-998	309	9	12	12	NUM
ijassa-998	309	10	.	.	PUNCT
ijassa-998	310	1	ledzewicz	ledzewicz	NOUN
ijassa-998	310	2	,	,	PUNCT
ijassa-998	310	3	u.	u.	PROPN
ijassa-998	310	4	,	,	PUNCT
ijassa-998	310	5	schättler	schättler	PRON
ijassa-998	310	6	,	,	PUNCT
ijassa-998	310	7	h.	h.	PROPN
ijassa-998	310	8	(	(	PUNCT
ijassa-998	310	9	2006	2006	NUM
ijassa-998	310	10	)	)	PUNCT
ijassa-998	310	11	,	,	PUNCT
ijassa-998	310	12	application	application	NOUN
ijassa-998	310	13	of	of	ADP
ijassa-998	310	14	optimal	optimal	ADJ
ijassa-998	310	15	control	control	NOUN
ijassa-998	310	16	to	to	ADP
ijassa-998	310	17	a	a	DET
ijassa-998	310	18	system	system	NOUN
ijassa-998	310	19	describing	describe	VERB
ijassa-998	310	20	tumor	tumor	NOUN
ijassa-998	310	21	anti	anti	ADJ
ijassa-998	310	22	-	-	ADJ
ijassa-998	310	23	angiogenesis	angiogenesis	ADJ
ijassa-998	310	24	,	,	PUNCT
ijassa-998	310	25	proceedings	proceeding	NOUN
ijassa-998	310	26	of	of	ADP
ijassa-998	310	27	the	the	DET
ijassa-998	310	28	17th	17th	ADJ
ijassa-998	310	29	international	international	ADJ
ijassa-998	310	30	symposium	symposium	NOUN
ijassa-998	310	31	on	on	ADP
ijassa-998	310	32	mathematical	mathematical	ADJ
ijassa-998	310	33	theory	theory	NOUN
ijassa-998	310	34	of	of	ADP
ijassa-998	310	35	networks	network	NOUN
ijassa-998	310	36	and	and	CCONJ
ijassa-998	310	37	systems	system	NOUN
ijassa-998	310	38	(	(	PUNCT
ijassa-998	310	39	mtns	mtns	PROPN
ijassa-998	310	40	)	)	PUNCT
ijassa-998	310	41	,	,	PUNCT
ijassa-998	310	42	kyoto	kyoto	PROPN
ijassa-998	310	43	,	,	PUNCT
ijassa-998	310	44	japan	japan	PROPN
ijassa-998	310	45	,	,	PUNCT
ijassa-998	310	46	478–484	478–484	NUM
ijassa-998	310	47	.	.	PUNCT
ijassa-998	311	1	13	13	NUM
ijassa-998	311	2	.	.	X
ijassa-998	312	1	ledzewicz	ledzewicz	NOUN
ijassa-998	312	2	,	,	PUNCT
ijassa-998	312	3	u.	u.	PROPN
ijassa-998	312	4	,	,	PUNCT
ijassa-998	312	5	schättler	schättler	PRON
ijassa-998	312	6	,	,	PUNCT
ijassa-998	312	7	h.	h.	PROPN
ijassa-998	312	8	(	(	PUNCT
ijassa-998	312	9	2005	2005	NUM
ijassa-998	312	10	)	)	PUNCT
ijassa-998	312	11	,	,	PUNCT
ijassa-998	312	12	a	a	DET
ijassa-998	312	13	synthesis	synthesis	NOUN
ijassa-998	312	14	of	of	ADP
ijassa-998	312	15	optimal	optimal	ADJ
ijassa-998	312	16	controls	control	NOUN
ijassa-998	312	17	for	for	ADP
ijassa-998	312	18	a	a	DET
ijassa-998	312	19	model	model	NOUN
ijassa-998	312	20	of	of	ADP
ijassa-998	312	21	tumor	tumor	NOUN
ijassa-998	312	22	growth	growth	NOUN
ijassa-998	312	23	under	under	ADP
ijassa-998	312	24	angiogenic	angiogenic	ADJ
ijassa-998	312	25	inhibitors	inhibitor	NOUN
ijassa-998	312	26	,	,	PUNCT
ijassa-998	312	27	proceedings	proceeding	NOUN
ijassa-998	312	28	of	of	ADP
ijassa-998	312	29	the	the	DET
ijassa-998	312	30	44th	44th	ADJ
ijassa-998	312	31	ieee	ieee	NOUN
ijassa-998	312	32	conference	conference	NOUN
ijassa-998	312	33	on	on	ADP
ijassa-998	312	34	decision	decision	NOUN
ijassa-998	312	35	and	and	CCONJ
ijassa-998	312	36	control	control	NOUN
ijassa-998	312	37	,	,	PUNCT
ijassa-998	312	38	945–950	945–950	NUM
ijassa-998	312	39	.	.	PUNCT
ijassa-998	313	1	14	14	NUM
ijassa-998	313	2	.	.	X
ijassa-998	313	3	miyamoto	miyamoto	PROPN
ijassa-998	313	4	,	,	PUNCT
ijassa-998	313	5	h.	h.	PROPN
ijassa-998	313	6	,	,	PUNCT
ijassa-998	313	7	messing	messing	NOUN
ijassa-998	313	8	,	,	PUNCT
ijassa-998	313	9	e.m	e.m	PROPN
ijassa-998	313	10	.	.	PROPN
ijassa-998	313	11	,	,	PUNCT
ijassa-998	313	12	chang	chang	PROPN
ijassa-998	313	13	,	,	PUNCT
ijassa-998	313	14	c.	c.	PROPN
ijassa-998	313	15	(	(	PUNCT
ijassa-998	313	16	2004	2004	NUM
ijassa-998	313	17	)	)	PUNCT
ijassa-998	313	18	,	,	PUNCT
ijassa-998	313	19	androgen	androgen	NOUN
ijassa-998	313	20	deprivation	deprivation	NOUN
ijassa-998	313	21	therapy	therapy	NOUN
ijassa-998	313	22	for	for	ADP
ijassa-998	313	23	prostate	prostate	NOUN
ijassa-998	313	24	cancer	cancer	NOUN
ijassa-998	313	25	:	:	PUNCT
ijassa-998	313	26	current	current	ADJ
ijassa-998	313	27	status	status	NOUN
ijassa-998	313	28	and	and	CCONJ
ijassa-998	313	29	future	future	ADJ
ijassa-998	313	30	prospects	prospect	NOUN
ijassa-998	313	31	,	,	PUNCT
ijassa-998	313	32	prostate	prostate	NOUN
ijassa-998	313	33	,	,	PUNCT
ijassa-998	313	34	61	61	NUM
ijassa-998	313	35	,	,	PUNCT
ijassa-998	313	36	332–353	332–353	NUM
ijassa-998	313	37	.	.	NOUN
ijassa-998	313	38	15	15	NUM
ijassa-998	313	39	.	.	PUNCT
ijassa-998	314	1	murray	murray	PROPN
ijassa-998	314	2	,	,	PUNCT
ijassa-998	314	3	j.m	j.m	PROPN
ijassa-998	314	4	.	.	PROPN
ijassa-998	314	5	(	(	PUNCT
ijassa-998	314	6	1990	1990	NUM
ijassa-998	314	7	)	)	PUNCT
ijassa-998	314	8	,	,	PUNCT
ijassa-998	314	9	optimal	optimal	ADJ
ijassa-998	314	10	control	control	NOUN
ijassa-998	314	11	for	for	ADP
ijassa-998	314	12	a	a	DET
ijassa-998	314	13	cancer	cancer	NOUN
ijassa-998	314	14	chemotherapy	chemotherapy	NOUN
ijassa-998	314	15	problem	problem	NOUN
ijassa-998	314	16	with	with	ADP
ijassa-998	314	17	general	general	ADJ
ijassa-998	314	18	growth	growth	NOUN
ijassa-998	314	19	and	and	CCONJ
ijassa-998	314	20	loss	loss	NOUN
ijassa-998	314	21	functions	function	NOUN
ijassa-998	314	22	,	,	PUNCT
ijassa-998	314	23	math	math	PROPN
ijassa-998	314	24	biosci	biosci	PROPN
ijassa-998	314	25	.	.	PUNCT
ijassa-998	314	26	,	,	PUNCT
ijassa-998	314	27	98(2	98(2	NUM
ijassa-998	314	28	)	)	PUNCT
ijassa-998	314	29	,	,	PUNCT
ijassa-998	314	30	273–287	273–287	NUM
ijassa-998	314	31	.	.	PUNCT
ijassa-998	315	1	16	16	NUM
ijassa-998	315	2	.	.	PUNCT
ijassa-998	315	3	pontryagin	pontryagin	NOUN
ijassa-998	315	4	,	,	PUNCT
ijassa-998	315	5	l.s	l.s	PROPN
ijassa-998	315	6	.	.	PROPN
ijassa-998	315	7	,	,	PUNCT
ijassa-998	315	8	boltyanskii	boltyanskii	PROPN
ijassa-998	315	9	,	,	PUNCT
ijassa-998	315	10	v.g	v.g	PROPN
ijassa-998	315	11	.	.	PROPN
ijassa-998	315	12	,	,	PUNCT
ijassa-998	315	13	gamkrelidze	gamkrelidze	PROPN
ijassa-998	315	14	,	,	PUNCT
ijassa-998	315	15	r.v	r.v	PROPN
ijassa-998	315	16	.	.	PROPN
ijassa-998	315	17	&	&	CCONJ
ijassa-998	315	18	mishchenko	mishchenko	PROPN
ijassa-998	315	19	ef	ef	PROPN
ijassa-998	315	20	(	(	PUNCT
ijassa-998	315	21	1962	1962	NUM
ijassa-998	315	22	)	)	PUNCT
ijassa-998	315	23	,	,	PUNCT
ijassa-998	315	24	the	the	DET
ijassa-998	315	25	mathematical	mathematical	ADJ
ijassa-998	315	26	theory	theory	NOUN
ijassa-998	315	27	of	of	ADP
ijassa-998	315	28	optimal	optimal	ADJ
ijassa-998	315	29	processes	process	NOUN
ijassa-998	315	30	,	,	PUNCT
ijassa-998	315	31	interscience	interscience	NOUN
ijassa-998	315	32	publishers	publisher	NOUN
ijassa-998	315	33	.	.	PUNCT
ijassa-998	316	1	17	17	NUM
ijassa-998	316	2	.	.	PUNCT
ijassa-998	317	1	rubinow	rubinow	PROPN
ijassa-998	317	2	s.i	s.i	PROPN
ijassa-998	317	3	.	.	PROPN
ijassa-998	317	4	,	,	PUNCT
ijassa-998	317	5	lebowitz	lebowitz	PROPN
ijassa-998	317	6	j.l	j.l	PROPN
ijassa-998	317	7	.	.	PUNCT
ijassa-998	317	8	(	(	PUNCT
ijassa-998	317	9	1976	1976	NUM
ijassa-998	317	10	)	)	PUNCT
ijassa-998	317	11	,	,	PUNCT
ijassa-998	317	12	a	a	DET
ijassa-998	317	13	mathematical	mathematical	ADJ
ijassa-998	317	14	model	model	NOUN
ijassa-998	317	15	of	of	ADP
ijassa-998	317	16	the	the	DET
ijassa-998	317	17	chemotherapeutic	chemotherapeutic	ADJ
ijassa-998	317	18	treatment	treatment	NOUN
ijassa-998	317	19	of	of	ADP
ijassa-998	317	20	acute	acute	ADJ
ijassa-998	317	21	myeloblastic	myeloblastic	ADJ
ijassa-998	317	22	leukemia	leukemia	NOUN
ijassa-998	317	23	,	,	PUNCT
ijassa-998	317	24	biophys	biophy	NOUN
ijassa-998	317	25	.	.	PUNCT
ijassa-998	318	1	j.	j.	PROPN
ijassa-998	318	2	,	,	PUNCT
ijassa-998	318	3	1257–1271	1257–1271	NUM
ijassa-998	318	4	.	.	PUNCT
ijassa-998	319	1	18	18	NUM
ijassa-998	319	2	.	.	X
ijassa-998	319	3	seidenfeld	seidenfeld	PROPN
ijassa-998	319	4	j.	j.	PROPN
ijassa-998	319	5	,	,	PUNCT
ijassa-998	319	6	et	et	PROPN
ijassa-998	319	7	al	al	PROPN
ijassa-998	319	8	.	.	PUNCT
ijassa-998	320	1	(	(	PUNCT
ijassa-998	320	2	2000	2000	NUM
ijassa-998	320	3	)	)	PUNCT
ijassa-998	320	4	,	,	PUNCT
ijassa-998	320	5	single	single	ADJ
ijassa-998	320	6	-	-	PUNCT
ijassa-998	320	7	therapy	therapy	NOUN
ijassa-998	320	8	androgen	androgen	NOUN
ijassa-998	320	9	suppression	suppression	NOUN
ijassa-998	320	10	in	in	ADP
ijassa-998	320	11	men	man	NOUN
ijassa-998	320	12	with	with	ADP
ijassa-998	320	13	advanced	advanced	ADJ
ijassa-998	320	14	prostate	prostate	NOUN
ijassa-998	320	15	cancer	cancer	NOUN
ijassa-998	320	16	:	:	PUNCT
ijassa-998	320	17	a	a	DET
ijassa-998	320	18	systematic	systematic	ADJ
ijassa-998	320	19	review	review	NOUN
ijassa-998	320	20	and	and	CCONJ
ijassa-998	320	21	meta	meta	ADJ
ijassa-998	320	22	-	-	PUNCT
ijassa-998	320	23	analysis	analysis	NOUN
ijassa-998	320	24	,	,	PUNCT
ijassa-998	320	25	ann	ann	PROPN
ijassa-998	320	26	intern	intern	NOUN
ijassa-998	320	27	med	me	VERB
ijassa-998	320	28	,	,	PUNCT
ijassa-998	320	29	132	132	NUM
ijassa-998	320	30	,	,	PUNCT
ijassa-998	320	31	566–577	566–577	NUM
ijassa-998	320	32	.	.	NOUN
ijassa-998	321	1	19	19	NUM
ijassa-998	321	2	.	.	X
ijassa-998	321	3	suzuki	suzuki	PROPN
ijassa-998	321	4	,	,	PUNCT
ijassa-998	321	5	y.	y.	PROPN
ijassa-998	321	6	,	,	PUNCT
ijassa-998	321	7	sakai	sakai	PROPN
ijassa-998	321	8	,	,	PUNCT
ijassa-998	321	9	d.	d.	PROPN
ijassa-998	321	10	,	,	PUNCT
ijassa-998	321	11	nomura	nomura	NOUN
ijassa-998	321	12	,	,	PUNCT
ijassa-998	321	13	t.	t.	PROPN
ijassa-998	321	14	,	,	PUNCT
ijassa-998	321	15	hirata	hirata	NOUN
ijassa-998	321	16	,	,	PUNCT
ijassa-998	321	17	y.	y.	PROPN
ijassa-998	321	18	and	and	CCONJ
ijassa-998	321	19	aihara	aihara	PROPN
ijassa-998	321	20	,	,	PUNCT
ijassa-998	321	21	k.	k.	PROPN
ijassa-998	321	22	(	(	PUNCT
ijassa-998	321	23	2014	2014	NUM
ijassa-998	321	24	)	)	PUNCT
ijassa-998	321	25	,	,	PUNCT
ijassa-998	321	26	a	a	DET
ijassa-998	321	27	new	new	ADJ
ijassa-998	321	28	protocol	protocol	NOUN
ijassa-998	321	29	for	for	ADP
ijassa-998	321	30	intermittent	intermittent	ADJ
ijassa-998	321	31	androgen	androgen	NOUN
ijassa-998	321	32	suppression	suppression	NOUN
ijassa-998	321	33	therapy	therapy	NOUN
ijassa-998	321	34	of	of	ADP
ijassa-998	321	35	prostate	prostate	NOUN
ijassa-998	321	36	cancer	cancer	NOUN
ijassa-998	321	37	with	with	ADP
ijassa-998	321	38	unstable	unstable	ADJ
ijassa-998	321	39	saddle	saddle	NOUN
ijassa-998	321	40	-	-	PUNCT
ijassa-998	321	41	point	point	NOUN
ijassa-998	321	42	dynamics	dynamic	NOUN
ijassa-998	321	43	,	,	PUNCT
ijassa-998	321	44	journal	journal	NOUN
ijassa-998	321	45	of	of	ADP
ijassa-998	321	46	theoretical	theoretical	ADJ
ijassa-998	321	47	biology	biology	NOUN
ijassa-998	321	48	,	,	PUNCT
ijassa-998	321	49	350	350	NUM
ijassa-998	321	50	,	,	PUNCT
ijassa-998	321	51	1–16	1–16	NOUN
ijassa-998	321	52	.	.	PUNCT
ijassa-998	322	1	20	20	NUM
ijassa-998	322	2	.	.	PUNCT
ijassa-998	322	3	swanson	swanson	PROPN
ijassa-998	322	4	,	,	PUNCT
ijassa-998	322	5	k.r	k.r	PROPN
ijassa-998	322	6	.	.	PROPN
ijassa-998	322	7	,	,	PUNCT
ijassa-998	322	8	true	true	ADJ
ijassa-998	322	9	,	,	PUNCT
ijassa-998	322	10	l.d	l.d	PROPN
ijassa-998	322	11	.	.	PROPN
ijassa-998	322	12	,	,	PUNCT
ijassa-998	322	13	lin	lin	PROPN
ijassa-998	322	14	,	,	PUNCT
ijassa-998	322	15	d.w	d.w	PROPN
ijassa-998	322	16	.	.	PROPN
ijassa-998	322	17	,	,	PUNCT
ijassa-998	322	18	buhler	buhler	PROPN
ijassa-998	322	19	,	,	PUNCT
ijassa-998	322	20	k.r	k.r	PROPN
ijassa-998	322	21	.	.	PROPN
ijassa-998	322	22	,	,	PUNCT
ijassa-998	322	23	vessella	vessella	PROPN
ijassa-998	322	24	,	,	PUNCT
ijassa-998	322	25	r.	r.	PROPN
ijassa-998	322	26	and	and	CCONJ
ijassa-998	322	27	murray	murray	PROPN
ijassa-998	322	28	,	,	PUNCT
ijassa-998	322	29	j.d	j.d	PROPN
ijassa-998	322	30	.	.	PROPN
ijassa-998	322	31	(	(	PUNCT
ijassa-998	322	32	2001	2001	NUM
ijassa-998	322	33	)	)	PUNCT
ijassa-998	322	34	,	,	PUNCT
ijassa-998	322	35	a	a	DET
ijassa-998	322	36	quantitative	quantitative	ADJ
ijassa-998	322	37	model	model	NOUN
ijassa-998	322	38	for	for	ADP
ijassa-998	322	39	the	the	DET
ijassa-998	322	40	dynamics	dynamic	NOUN
ijassa-998	322	41	of	of	ADP
ijassa-998	322	42	serum	serum	NOUN
ijassa-998	322	43	prostate	prostate	NOUN
ijassa-998	322	44	-	-	PUNCT
ijassa-998	322	45	specific	specific	ADJ
ijassa-998	322	46	antigen	antigen	NOUN
ijassa-998	322	47	as	as	ADP
ijassa-998	322	48	a	a	DET
ijassa-998	322	49	marker	marker	NOUN
ijassa-998	322	50	for	for	ADP
ijassa-998	322	51	cancerous	cancerous	ADJ
ijassa-998	322	52	growth	growth	NOUN
ijassa-998	322	53	:	:	PUNCT
ijassa-998	322	54	an	an	DET
ijassa-998	322	55	explanation	explanation	NOUN
ijassa-998	322	56	for	for	ADP
ijassa-998	322	57	a	a	DET
ijassa-998	322	58	medical	medical	ADJ
ijassa-998	322	59	anomaly	anomaly	NOUN
ijassa-998	322	60	,	,	PUNCT
ijassa-998	322	61	the	the	DET
ijassa-998	322	62	american	american	PROPN
ijassa-998	322	63	journal	journal	PROPN
ijassa-998	322	64	of	of	ADP
ijassa-998	322	65	pathology	pathology	PROPN
ijassa-998	322	66	,	,	PUNCT
ijassa-998	322	67	158(6	158(6	NUM
ijassa-998	322	68	)	)	PUNCT
ijassa-998	322	69	,	,	PUNCT
ijassa-998	322	70	2195–2199	2195–2199	NUM
ijassa-998	322	71	.	.	PUNCT
ijassa-998	323	1	21	21	NUM
ijassa-998	323	2	.	.	PUNCT
ijassa-998	323	3	swan	swan	PROPN
ijassa-998	323	4	,	,	PUNCT
ijassa-998	323	5	g.w	g.w	PROPN
ijassa-998	323	6	.	.	PROPN
ijassa-998	323	7	(	(	PUNCT
ijassa-998	323	8	1990	1990	NUM
ijassa-998	323	9	)	)	PUNCT
ijassa-998	323	10	,	,	PUNCT
ijassa-998	323	11	role	role	NOUN
ijassa-998	323	12	of	of	ADP
ijassa-998	323	13	optimal	optimal	ADJ
ijassa-998	323	14	control	control	NOUN
ijassa-998	323	15	theory	theory	NOUN
ijassa-998	323	16	in	in	ADP
ijassa-998	323	17	cancer	cancer	NOUN
ijassa-998	323	18	chemotherapy	chemotherapy	NOUN
ijassa-998	323	19	,	,	PUNCT
ijassa-998	323	20	math	math	PROPN
ijassa-998	323	21	biosci	biosci	PROPN
ijassa-998	323	22	.	.	PUNCT
ijassa-998	323	23	,	,	PUNCT
ijassa-998	323	24	101(2	101(2	NUM
ijassa-998	323	25	)	)	PUNCT
ijassa-998	323	26	,	,	PUNCT
ijassa-998	323	27	237–284	237–284	NUM
ijassa-998	323	28	.	.	PUNCT
ijassa-998	324	1	22	22	NUM
ijassa-998	324	2	.	.	PUNCT
ijassa-998	325	1	todorov	todorov	PROPN
ijassa-998	325	2	,	,	PUNCT
ijassa-998	325	3	y.	y.	PROPN
ijassa-998	325	4	,	,	PUNCT
ijassa-998	325	5	nuernberg	nuernberg	PROPN
ijassa-998	325	6	,	,	PUNCT
ijassa-998	325	7	f.	f.	PROPN
ijassa-998	325	8	(	(	PUNCT
ijassa-998	325	9	2014	2014	NUM
ijassa-998	325	10	)	)	PUNCT
ijassa-998	325	11	,	,	PUNCT
ijassa-998	325	12	optimal	optimal	ADJ
ijassa-998	325	13	therapy	therapy	NOUN
ijassa-998	325	14	protocols	protocol	NOUN
ijassa-998	325	15	in	in	ADP
ijassa-998	325	16	the	the	DET
ijassa-998	325	17	mathematical	mathematical	ADJ
ijassa-998	325	18	model	model	NOUN
ijassa-998	325	19	of	of	ADP
ijassa-998	325	20	acute	acute	ADJ
ijassa-998	325	21	leukemia	leukemia	NOUN
ijassa-998	325	22	with	with	ADP
ijassa-998	325	23	several	several	ADJ
ijassa-998	325	24	phase	phase	NOUN
ijassa-998	325	25	constraints	constraint	NOUN
ijassa-998	325	26	,	,	PUNCT
ijassa-998	325	27	ocam	ocam	NOUN
ijassa-998	325	28	,	,	PUNCT
ijassa-998	325	29	35(5	35(5	NUM
ijassa-998	325	30	)	)	PUNCT
ijassa-998	325	31	,	,	PUNCT
ijassa-998	325	32	559–574	559–574	NUM
ijassa-998	325	33	.	.	PUNCT
ijassa-998	326	1	copyright	copyright	NOUN
ijassa-998	326	2	c	c	ADP
ijassa-998	326	3	©	©	PROPN
ijassa-998	326	4	2020	2020	NUM
ijassa-998	326	5	assa	assa	NOUN
ijassa-998	326	6	.	.	PUNCT
ijassa-998	327	1	adv	adv	PROPN
ijassa-998	327	2	syst	syst	PROPN
ijassa-998	327	3	sci	sci	PROPN
ijassa-998	327	4	appl	appl	PROPN
ijassa-998	327	5	(	(	PUNCT
ijassa-998	327	6	2020	2020	NUM
ijassa-998	327	7	)	)	PUNCT
ijassa-998	327	8	on	on	ADP
ijassa-998	327	9	optimal	optimal	ADJ
ijassa-998	327	10	therapy	therapy	NOUN
ijassa-998	327	11	protocols	protocol	NOUN
ijassa-998	327	12	in	in	ADP
ijassa-998	327	13	the	the	DET
ijassa-998	327	14	math	math	NOUN
ijassa-998	327	15	.	.	PUNCT
ijassa-998	328	1	model	model	NOUN
ijassa-998	328	2	of	of	ADP
ijassa-998	328	3	prostate	prostate	NOUN
ijassa-998	328	4	cancer	cancer	NOUN
ijassa-998	328	5	progression101	progression101	PROPN
ijassa-998	328	6	a.	a.	NOUN
ijassa-998	328	7	appendixes	appendix	NOUN
ijassa-998	328	8	a.1	a.1	PROPN
ijassa-998	328	9	.	.	PUNCT
ijassa-998	329	1	model	model	PROPN
ijassa-998	329	2	parameter	parameter	PROPN
ijassa-998	329	3	values	value	VERB
ijassa-998	329	4	the	the	DET
ijassa-998	329	5	following	follow	VERB
ijassa-998	329	6	values	value	NOUN
ijassa-998	329	7	were	be	AUX
ijassa-998	329	8	used	use	VERB
ijassa-998	329	9	for	for	ADP
ijassa-998	329	10	the	the	DET
ijassa-998	329	11	model	model	NOUN
ijassa-998	329	12	parameters	parameter	NOUN
ijassa-998	329	13	(	(	PUNCT
ijassa-998	329	14	taken	take	VERB
ijassa-998	329	15	from	from	ADP
ijassa-998	329	16	[	[	X
ijassa-998	329	17	11	11	NUM
ijassa-998	329	18	]	]	NUM
ijassa-998	329	19	)	)	PUNCT
ijassa-998	329	20	.	.	PUNCT
ijassa-998	330	1	parameter	parameter	PROPN
ijassa-998	330	2	value	value	NOUN
ijassa-998	330	3	parameter	parameter	NOUN
ijassa-998	330	4	value	value	NOUN
ijassa-998	330	5	parameter	parameter	NOUN
ijassa-998	330	6	value	value	NOUN
ijassa-998	330	7	ηe	ηe	ADP
ijassa-998	330	8	110.24	110.24	NUM
ijassa-998	330	9	δe	δe	NOUN
ijassa-998	330	10	0.0081	0.0081	NUM
ijassa-998	330	11	δ	δ	NOUN
ijassa-998	330	12	0.00405	0.00405	NUM
ijassa-998	330	13	γ	γ	X
ijassa-998	330	14	0.1	0.1	NUM
ijassa-998	330	15	µe0	µe0	PROPN
ijassa-998	330	16	0.22	0.22	NUM
ijassa-998	330	17	µ0	µ0	NOUN
ijassa-998	330	18	0.1	0.1	NUM
ijassa-998	330	19	ke	ke	NOUN
ijassa-998	330	20	0.889	0.889	NUM
ijassa-998	330	21	k	k	NOUN
ijassa-998	330	22	0.99	0.99	NUM
ijassa-998	330	23	ats	ats	PROPN
ijassa-998	330	24	1.00	1.00	NUM
ijassa-998	330	25	bts	bt	NOUN
ijassa-998	330	26	22.23	22.23	NUM
ijassa-998	330	27	cts	ct	NOUN
ijassa-998	330	28	0.23	0.23	NUM
ijassa-998	330	29	ktf	ktf	PROPN
ijassa-998	330	30	0.14	0.14	NUM
ijassa-998	330	31	ktr	ktr	PROPN
ijassa-998	330	32	0.07	0.07	NUM
ijassa-998	330	33	αp	αp	NOUN
ijassa-998	330	34	0.001515	0.001515	NUM
ijassa-998	330	35	ε	ε	PROPN
ijassa-998	330	36	0.009	0.009	NUM
ijassa-998	330	37	λd	λd	NOUN
ijassa-998	330	38	log(2	log(2	NOUN
ijassa-998	330	39	)	)	PUNCT
ijassa-998	330	40	9	9	NUM
ijassa-998	330	41	λp	λp	SYM
ijassa-998	330	42	log(2	log(2	NOUN
ijassa-998	330	43	)	)	PUNCT
ijassa-998	330	44	12.3	12.3	NUM
ijassa-998	330	45	λat	λat	NOUN
ijassa-998	330	46	log(2	log(2	NOUN
ijassa-998	330	47	)	)	PUNCT
ijassa-998	330	48	3	3	NUM
ijassa-998	330	49	βm	βm	VERB
ijassa-998	330	50	0.003	0.003	NUM
ijassa-998	330	51	βn	βn	NOUN
ijassa-998	330	52	0.002	0.002	NUM
ijassa-998	330	53	βt	βt	NOUN
ijassa-998	330	54	4.569	4.569	NUM
ijassa-998	330	55	pn	pn	NOUN
ijassa-998	330	56	10	10	NUM
ijassa-998	330	57	pm	pm	NOUN
ijassa-998	330	58	10	10	NUM
ijassa-998	330	59	kp	kp	PROPN
ijassa-998	330	60	7	7	NUM
ijassa-998	330	61	γp	γp	NOUN
ijassa-998	330	62	0.6	0.6	NUM
ijassa-998	330	63	104	104	NUM
ijassa-998	330	64	kdf	kdf	PROPN
ijassa-998	330	65	0.018	0.018	NUM
ijassa-998	330	66	kdr	kdr	PROPN
ijassa-998	330	67	0.053	0.053	NUM
ijassa-998	330	68	100	100	NUM
ijassa-998	330	69	kt	kt	PROPN
ijassa-998	330	70	0.104	0.104	NUM
ijassa-998	330	71	aet	aet	NOUN
ijassa-998	330	72	1.62	1.62	NUM
ijassa-998	330	73	λr	λr	NOUN
ijassa-998	330	74	log(2	log(2	NOUN
ijassa-998	330	75	)	)	PUNCT
ijassa-998	330	76	3	3	NUM
ijassa-998	330	77	λa	λa	NOUN
ijassa-998	330	78	log(2	log(2	NOUN
ijassa-998	330	79	)	)	PUNCT
ijassa-998	330	80	3	3	NUM
ijassa-998	330	81	λt	λt	ADP
ijassa-998	330	82	log(2	log(2	NOUN
ijassa-998	330	83	)	)	PUNCT
ijassa-998	330	84	3	3	NUM
ijassa-998	330	85	av	av	PROPN
ijassa-998	330	86	18.397	18.397	NUM
ijassa-998	330	87	bv	bv	PROPN
ijassa-998	330	88	67.753	67.753	NUM
ijassa-998	330	89	cv	cv	NOUN
ijassa-998	330	90	28.4	28.4	NUM
ijassa-998	330	91	dv	dv	PROPN
ijassa-998	330	92	12	12	NUM
ijassa-998	330	93	vc	vc	PROPN
ijassa-998	330	94	5.56	5.56	NUM
ijassa-998	330	95	106	106	NUM
ijassa-998	330	96	r0	r0	NOUN
ijassa-998	330	97	e	e	NOUN
ijassa-998	330	98	90	90	NUM
ijassa-998	330	99	0.002622	0.002622	NUM
ijassa-998	330	100	β	β	NOUN
ijassa-998	330	101	table	table	NOUN
ijassa-998	330	102	a.2	a.2	PRON
ijassa-998	330	103	.	.	PUNCT
ijassa-998	331	1	parameters	parameter	NOUN
ijassa-998	331	2	of	of	ADP
ijassa-998	331	3	the	the	DET
ijassa-998	331	4	model	model	NOUN
ijassa-998	331	5	more	more	ADV
ijassa-998	331	6	detailed	detailed	ADJ
ijassa-998	331	7	information	information	NOUN
ijassa-998	331	8	is	be	AUX
ijassa-998	331	9	given	give	VERB
ijassa-998	331	10	in	in	ADP
ijassa-998	331	11	[	[	PUNCT
ijassa-998	331	12	11	11	NUM
ijassa-998	331	13	]	]	PUNCT
ijassa-998	331	14	.	.	PUNCT
ijassa-998	332	1	a.2	a.2	PUNCT
ijassa-998	332	2	.	.	PUNCT
ijassa-998	333	1	dynamical	dynamical	ADJ
ijassa-998	333	2	analysis	analysis	NOUN
ijassa-998	333	3	the	the	DET
ijassa-998	333	4	motivation	motivation	NOUN
ijassa-998	333	5	for	for	ADP
ijassa-998	333	6	the	the	DET
ijassa-998	333	7	construction	construction	NOUN
ijassa-998	333	8	of	of	ADP
ijassa-998	333	9	the	the	DET
ijassa-998	333	10	alternative	alternative	ADJ
ijassa-998	333	11	control	control	NOUN
ijassa-998	333	12	strategy	strategy	NOUN
ijassa-998	333	13	rests	rest	VERB
ijassa-998	333	14	upon	upon	SCONJ
ijassa-998	333	15	the	the	DET
ijassa-998	333	16	asymptotically	asymptotically	ADJ
ijassa-998	333	17	behaviour	behaviour	NOUN
ijassa-998	333	18	of	of	ADP
ijassa-998	333	19	the	the	DET
ijassa-998	333	20	considered	consider	VERB
ijassa-998	333	21	system	system	NOUN
ijassa-998	333	22	(	(	PUNCT
ijassa-998	333	23	3.4	3.4	NUM
ijassa-998	333	24	)	)	PUNCT
ijassa-998	333	25	.	.	PUNCT
ijassa-998	334	1	a	a	DET
ijassa-998	334	2	relocation	relocation	NOUN
ijassa-998	334	3	of	of	ADP
ijassa-998	334	4	an	an	DET
ijassa-998	334	5	asymptotic	asymptotic	ADJ
ijassa-998	334	6	stable	stable	ADJ
ijassa-998	334	7	critical	critical	ADJ
ijassa-998	334	8	point	point	NOUN
ijassa-998	334	9	in	in	ADP
ijassa-998	334	10	order	order	NOUN
ijassa-998	334	11	to	to	PART
ijassa-998	334	12	minimize	minimize	VERB
ijassa-998	334	13	the	the	DET
ijassa-998	334	14	functional	functional	ADJ
ijassa-998	334	15	(	(	PUNCT
ijassa-998	334	16	3.3	3.3	NUM
ijassa-998	334	17	)	)	PUNCT
ijassa-998	334	18	provides	provide	VERB
ijassa-998	334	19	the	the	DET
ijassa-998	334	20	alternative	alternative	ADJ
ijassa-998	334	21	therapy	therapy	NOUN
ijassa-998	334	22	strategy	strategy	NOUN
ijassa-998	334	23	.	.	PUNCT
ijassa-998	335	1	therefore	therefore	ADV
ijassa-998	335	2	the	the	DET
ijassa-998	335	3	type	type	NOUN
ijassa-998	335	4	of	of	ADP
ijassa-998	335	5	the	the	DET
ijassa-998	335	6	nontrivial	nontrivial	ADJ
ijassa-998	335	7	critical	critical	ADJ
ijassa-998	335	8	point	point	NOUN
ijassa-998	335	9	given	give	VERB
ijassa-998	335	10	in	in	ADP
ijassa-998	335	11	(	(	PUNCT
ijassa-998	335	12	3.6	3.6	NUM
ijassa-998	335	13	)	)	PUNCT
ijassa-998	335	14	is	be	AUX
ijassa-998	335	15	analyzed	analyze	VERB
ijassa-998	335	16	.	.	PUNCT
ijassa-998	336	1	define	define	VERB
ijassa-998	336	2	the	the	DET
ijassa-998	336	3	jacobian	jacobian	PROPN
ijassa-998	336	4	j	j	PROPN
ijassa-998	336	5	=	=	SYM
ijassa-998	336	6	∂f	∂f	PROPN
ijassa-998	336	7	∂x	∂x	PROPN
ijassa-998	336	8	=	=	SYM
ijassa-998	336	9			PROPN
ijassa-998	336	10	∂e(t	∂e(t	X
ijassa-998	336	11	)	)	PUNCT
ijassa-998	336	12	∂e	∂e	PROPN
ijassa-998	336	13	∂e(t	∂e(t	PROPN
ijassa-998	336	14	)	)	PUNCT
ijassa-998	336	15	∂z	∂z	PROPN
ijassa-998	336	16	∂z(t	∂z(t	PROPN
ijassa-998	336	17	)	)	PUNCT
ijassa-998	336	18	∂e	∂e	PROPN
ijassa-998	336	19	∂z(t	∂z(t	PROPN
ijassa-998	336	20	)	)	PUNCT
ijassa-998	336	21	∂z	∂z	PROPN
ijassa-998	336	22			NOUN
ijassa-998	336	23	=	=	PUNCT
ijassa-998	336	24	µe(h)−	µe(h)−	NOUN
ijassa-998	336	25	2eµe(h	2eµe(h	NUM
ijassa-998	336	26	)	)	PUNCT
ijassa-998	336	27	ηe	ηe	ADP
ijassa-998	336	28	−	−	PROPN
ijassa-998	336	29	εz	εz	AUX
ijassa-998	336	30	ηe	ηe	ADP
ijassa-998	336	31	−	−	PROPN
ijassa-998	336	32	δe	δe	NOUN
ijassa-998	336	33	−εe	−εe	NOUN
ijassa-998	336	34	ηe	ηe	ADP
ijassa-998	336	35	0	0	NUM
ijassa-998	336	36	µ(h)−	µ(h)−	PROPN
ijassa-998	336	37	2zµ(h	2zµ(h	NUM
ijassa-998	336	38	)	)	PUNCT
ijassa-998	336	39	η	η	PROPN
ijassa-998	336	40	−	−	PROPN
ijassa-998	336	41	δ	δ	PROPN
ijassa-998	336	42			NOUN
ijassa-998	336	43	at	at	ADP
ijassa-998	336	44	the	the	DET
ijassa-998	336	45	considered	consider	VERB
ijassa-998	336	46	critical	critical	ADJ
ijassa-998	336	47	point	point	NOUN
ijassa-998	336	48	(	(	PUNCT
ijassa-998	336	49	3.6	3.6	NUM
ijassa-998	336	50	)	)	PUNCT
ijassa-998	336	51	holds	hold	VERB
ijassa-998	336	52	j	j	PROPN
ijassa-998	336	53	|(ē,z̄	|(ē,z̄	PROPN
ijassa-998	336	54	)	)	PUNCT
ijassa-998	337	1	=	=	SYM
ijassa-998	337	2	−µe(h̄	−µe(h̄	PROPN
ijassa-998	337	3	)	)	PUNCT
ijassa-998	338	1	+	+	CCONJ
ijassa-998	338	2	ēµe(h̄	ēµe(h̄	NOUN
ijassa-998	338	3	)	)	PUNCT
ijassa-998	338	4	ηe	ηe	ADP
ijassa-998	339	1	+	+	PUNCT
ijassa-998	339	2	δe	δe	ADP
ijassa-998	339	3	−εē	−εē	NUM
ijassa-998	339	4	ηe	ηe	ADP
ijassa-998	339	5	0	0	NUM
ijassa-998	339	6	−µ(h̄	−µ(h̄	NOUN
ijassa-998	339	7	)	)	PUNCT
ijassa-998	340	1	+	+	CCONJ
ijassa-998	340	2	δ	δ	PROPN
ijassa-998	340	3			PROPN
ijassa-998	340	4	.	.	PUNCT
ijassa-998	341	1	copyright	copyright	NOUN
ijassa-998	341	2	c	c	ADP
ijassa-998	341	3	©	©	PROPN
ijassa-998	341	4	2020	2020	NUM
ijassa-998	341	5	assa	assa	NOUN
ijassa-998	341	6	.	.	PUNCT
ijassa-998	342	1	adv	adv	PROPN
ijassa-998	342	2	syst	syst	PROPN
ijassa-998	342	3	sci	sci	PROPN
ijassa-998	342	4	appl	appl	PROPN
ijassa-998	342	5	(	(	PUNCT
ijassa-998	342	6	2020	2020	NUM
ijassa-998	342	7	)	)	PUNCT
ijassa-998	342	8	102	102	NUM
ijassa-998	342	9	m.-c	m.-c	NOUN
ijassa-998	342	10	.	.	PUNCT
ijassa-998	343	1	litzinger	litzinger	NOUN
ijassa-998	343	2	,	,	PUNCT
ijassa-998	343	3	y.	y.	PROPN
ijassa-998	343	4	todorov	todorov	PROPN
ijassa-998	343	5	,	,	PUNCT
ijassa-998	343	6	m.	m.	NOUN
ijassa-998	343	7	föller	föller	PROPN
ijassa-998	343	8	-	-	PUNCT
ijassa-998	343	9	nord	nord	PROPN
ijassa-998	343	10	,	,	PUNCT
ijassa-998	343	11	m.k	m.k	PROPN
ijassa-998	343	12	.	.	PUNCT
ijassa-998	343	13	chaudhary	chaudhary	PROPN
ijassa-998	343	14	,	,	PUNCT
ijassa-998	343	15	a.s	a.s	PROPN
ijassa-998	343	16	.	.	PROPN
ijassa-998	343	17	bratus	bratus	NOUN
ijassa-998	343	18	in	in	ADP
ijassa-998	343	19	order	order	NOUN
ijassa-998	343	20	to	to	PART
ijassa-998	343	21	analyze	analyze	VERB
ijassa-998	343	22	the	the	DET
ijassa-998	343	23	behaviour	behaviour	NOUN
ijassa-998	343	24	of	of	ADP
ijassa-998	343	25	the	the	DET
ijassa-998	343	26	considered	consider	VERB
ijassa-998	343	27	critical	critical	ADJ
ijassa-998	343	28	point	point	NOUN
ijassa-998	343	29	it	it	PRON
ijassa-998	343	30	is	be	AUX
ijassa-998	343	31	necessary	necessary	ADJ
ijassa-998	343	32	to	to	PART
ijassa-998	343	33	analyze	analyze	VERB
ijassa-998	343	34	the	the	DET
ijassa-998	343	35	sign	sign	NOUN
ijassa-998	343	36	of	of	ADP
ijassa-998	343	37	the	the	DET
ijassa-998	343	38	eigenvalues	eigenvalue	NOUN
ijassa-998	343	39	of	of	ADP
ijassa-998	343	40	the	the	DET
ijassa-998	343	41	jacobian	jacobian	ADJ
ijassa-998	343	42	.	.	PUNCT
ijassa-998	344	1	i.e.	i.e.	X
ijassa-998	344	2	,	,	PUNCT
ijassa-998	344	3	to	to	PART
ijassa-998	344	4	find	find	VERB
ijassa-998	344	5	the	the	DET
ijassa-998	344	6	roots	root	NOUN
ijassa-998	344	7	of	of	ADP
ijassa-998	344	8	the	the	DET
ijassa-998	344	9	polynomial	polynomial	NOUN
ijassa-998	344	10	defined	define	VERB
ijassa-998	344	11	by	by	ADP
ijassa-998	344	12	det(j	det(j	PROPN
ijassa-998	344	13	−	−	PROPN
ijassa-998	344	14	λē	λē	NOUN
ijassa-998	344	15	)	)	PUNCT
ijassa-998	345	1	=	=	SYM
ijassa-998	345	2	(	(	PUNCT
ijassa-998	345	3	−	−	NOUN
ijassa-998	345	4	µe(h̄	µe(h̄	NOUN
ijassa-998	345	5	)	)	PUNCT
ijassa-998	345	6	+	+	CCONJ
ijassa-998	345	7	ēµe(h̄	ēµe(h̄	NOUN
ijassa-998	345	8	)	)	PUNCT
ijassa-998	345	9	ηe	ηe	ADP
ijassa-998	346	1	+	+	PUNCT
ijassa-998	346	2	δe	δe	DET
ijassa-998	346	3	−	−	PROPN
ijassa-998	346	4	λ	λ	PROPN
ijassa-998	346	5	)	)	PUNCT
ijassa-998	346	6	(	(	PUNCT
ijassa-998	346	7	−	−	PROPN
ijassa-998	346	8	µ(h̄	µ(h̄	NUM
ijassa-998	346	9	)	)	PUNCT
ijassa-998	346	10	+	+	NUM
ijassa-998	346	11	δ	δ	PROPN
ijassa-998	346	12	−	−	PROPN
ijassa-998	346	13	λ	λ	PROPN
ijassa-998	346	14	)	)	PUNCT
ijassa-998	346	15	.	.	PUNCT
ijassa-998	347	1	the	the	DET
ijassa-998	347	2	eigenvalues	eigenvalue	NOUN
ijassa-998	347	3	λ1	λ1	ADJ
ijassa-998	347	4	,	,	PUNCT
ijassa-998	347	5	λ2	λ2	NOUN
ijassa-998	347	6	of	of	ADP
ijassa-998	347	7	j	j	PROPN
ijassa-998	347	8	are	be	AUX
ijassa-998	347	9	λ1	λ1	PROPN
ijassa-998	347	10	=	=	SYM
ijassa-998	347	11	−µ(h̄	−µ(h̄	NOUN
ijassa-998	347	12	)	)	PUNCT
ijassa-998	348	1	+	+	CCONJ
ijassa-998	348	2	δ	δ	X
ijassa-998	348	3	<	<	X
ijassa-998	348	4	0	0	PUNCT
ijassa-998	348	5	and	and	CCONJ
ijassa-998	348	6	λ2	λ2	NOUN
ijassa-998	348	7	=	=	SYM
ijassa-998	348	8	−µe(h̄	−µe(h̄	NOUN
ijassa-998	348	9	)	)	PUNCT
ijassa-998	349	1	+	+	CCONJ
ijassa-998	349	2	ēµe(h̄	ēµe(h̄	NOUN
ijassa-998	349	3	)	)	PUNCT
ijassa-998	349	4	ηe	ηe	X
ijassa-998	350	1	+	+	X
ijassa-998	350	2	δe	δe	VERB
ijassa-998	350	3	.	.	NOUN
ijassa-998	350	4	for	for	ADP
ijassa-998	350	5	the	the	DET
ijassa-998	350	6	given	give	VERB
ijassa-998	350	7	set	set	NOUN
ijassa-998	350	8	of	of	ADP
ijassa-998	350	9	parameters	parameter	NOUN
ijassa-998	350	10	(	(	PUNCT
ijassa-998	350	11	see	see	VERB
ijassa-998	350	12	a.1	a.1	NOUN
ijassa-998	350	13	)	)	PUNCT
ijassa-998	350	14	the	the	DET
ijassa-998	350	15	critical	critical	ADJ
ijassa-998	350	16	point	point	NOUN
ijassa-998	350	17	(	(	PUNCT
ijassa-998	350	18	ē	ē	NOUN
ijassa-998	350	19	,	,	PUNCT
ijassa-998	350	20	z̄	z̄	X
ijassa-998	350	21	)	)	PUNCT
ijassa-998	350	22	is	be	AUX
ijassa-998	350	23	always	always	ADV
ijassa-998	350	24	stable	stable	ADJ
ijassa-998	350	25	.	.	PUNCT
ijassa-998	351	1	a.3	a.3	X
ijassa-998	351	2	.	.	PUNCT
ijassa-998	352	1	optimal	optimal	ADJ
ijassa-998	352	2	control	control	NOUN
ijassa-998	352	3	without	without	ADP
ijassa-998	352	4	state	state	NOUN
ijassa-998	352	5	constraint	constraint	NOUN
ijassa-998	352	6	constructing	construct	VERB
ijassa-998	352	7	the	the	DET
ijassa-998	352	8	pontryagin	pontryagin	NOUN
ijassa-998	352	9	-	-	PUNCT
ijassa-998	352	10	hamilton	hamilton	PROPN
ijassa-998	352	11	function	function	NOUN
ijassa-998	352	12	[	[	X
ijassa-998	352	13	16	16	NUM
ijassa-998	352	14	]	]	PUNCT
ijassa-998	352	15	to	to	ADP
ijassa-998	352	16	the	the	DET
ijassa-998	352	17	problem	problem	NOUN
ijassa-998	352	18	(	(	PUNCT
ijassa-998	352	19	3	3	NUM
ijassa-998	352	20	)	)	PUNCT
ijassa-998	352	21	,	,	PUNCT
ijassa-998	352	22	(	(	PUNCT
ijassa-998	352	23	4	4	X
ijassa-998	352	24	)	)	PUNCT
ijassa-998	352	25	h	h	NOUN
ijassa-998	352	26	:	:	PUNCT
ijassa-998	352	27	=	=	SYM
ijassa-998	352	28	h(e	h(e	PROPN
ijassa-998	352	29	,	,	PUNCT
ijassa-998	352	30	z	z	NOUN
ijassa-998	352	31	,	,	PUNCT
ijassa-998	352	32	r	r	NOUN
ijassa-998	352	33	,	,	PUNCT
ijassa-998	352	34	d	d	PROPN
ijassa-998	352	35	,	,	PUNCT
ijassa-998	352	36	t	t	PROPN
ijassa-998	352	37	,	,	PUNCT
ijassa-998	352	38	a	a	PRON
ijassa-998	352	39	,	,	PUNCT
ijassa-998	352	40	at	at	ADP
ijassa-998	352	41	,	,	PUNCT
ijassa-998	352	42	p	p	X
ijassa-998	352	43	,	,	PUNCT
ijassa-998	352	44	h	h	NOUN
ijassa-998	352	45	,	,	PUNCT
ijassa-998	352	46	ψ0	ψ0	ADJ
ijassa-998	352	47	,	,	PUNCT
ijassa-998	352	48	ψ1	ψ1	NOUN
ijassa-998	352	49	,	,	PUNCT
ijassa-998	352	50	ψ2	ψ2	NOUN
ijassa-998	352	51	,	,	PUNCT
ijassa-998	352	52	ψ3	ψ3	NOUN
ijassa-998	352	53	,	,	PUNCT
ijassa-998	352	54	ψ4	ψ4	PROPN
ijassa-998	352	55	,	,	PUNCT
ijassa-998	352	56	ψ5	ψ5	PROPN
ijassa-998	352	57	,	,	PUNCT
ijassa-998	352	58	ψ6	ψ6	NOUN
ijassa-998	352	59	,	,	PUNCT
ijassa-998	352	60	ψ7	ψ7	PROPN
ijassa-998	352	61	,	,	PUNCT
ijassa-998	352	62	ψ8	ψ8	PROPN
ijassa-998	352	63	,	,	PUNCT
ijassa-998	352	64	ψ9	ψ9	PROPN
ijassa-998	352	65	,	,	PUNCT
ijassa-998	352	66	u	u	NOUN
ijassa-998	352	67	)	)	PUNCT
ijassa-998	352	68	=	=	PUNCT
ijassa-998	353	1	+	+	CCONJ
ijassa-998	353	2	ψ0(z	ψ0(z	PROPN
ijassa-998	353	3	)	)	PUNCT
ijassa-998	353	4	+	+	CCONJ
ijassa-998	353	5	ψ1	ψ1	NOUN
ijassa-998	353	6	(	(	PUNCT
ijassa-998	353	7	µee	µee	PROPN
ijassa-998	353	8	(	(	PUNCT
ijassa-998	353	9	1−	1−	NUM
ijassa-998	353	10	e	e	NOUN
ijassa-998	353	11	ηe	ηe	PROPN
ijassa-998	353	12	)	)	PUNCT
ijassa-998	353	13	−	−	PROPN
ijassa-998	353	14	εez	εez	INTJ
ijassa-998	353	15	ηe	ηe	ADP
ijassa-998	353	16	−	−	PROPN
ijassa-998	353	17	δee	δee	NOUN
ijassa-998	353	18	)	)	PUNCT
ijassa-998	354	1	+	+	CCONJ
ijassa-998	354	2	ψ2	ψ2	NOUN
ijassa-998	354	3	(	(	PUNCT
ijassa-998	354	4	µz(t	µz(t	X
ijassa-998	354	5	)	)	PUNCT
ijassa-998	354	6	(	(	PUNCT
ijassa-998	354	7	1−	1−	NUM
ijassa-998	354	8	z(t	z(t	NOUN
ijassa-998	354	9	)	)	PUNCT
ijassa-998	354	10	η	η	PROPN
ijassa-998	354	11	)	)	PUNCT
ijassa-998	354	12	−	−	NOUN
ijassa-998	354	13	δz(t	δz(t	NOUN
ijassa-998	354	14	)	)	PUNCT
ijassa-998	354	15	)	)	PUNCT
ijassa-998	355	1	+	+	PUNCT
ijassa-998	355	2	+	+	NUM
ijassa-998	355	3	ψ3	ψ3	NOUN
ijassa-998	355	4	(	(	PUNCT
ijassa-998	355	5	αr	αr	NUM
ijassa-998	355	6	−	−	PROPN
ijassa-998	356	1	λrr−	λrr−	PROPN
ijassa-998	356	2	kdf	kdf	PROPN
ijassa-998	356	3	rd	rd	PROPN
ijassa-998	356	4	+	+	CCONJ
ijassa-998	356	5	kdr	kdr	PROPN
ijassa-998	356	6	a−	a−	PROPN
ijassa-998	356	7	ktf	ktf	PROPN
ijassa-998	356	8	rt	rt	PROPN
ijassa-998	357	1	+	+	CCONJ
ijassa-998	357	2	ktr	ktr	PROPN
ijassa-998	357	3	a	a	PRON
ijassa-998	357	4	)	)	PUNCT
ijassa-998	358	1	+	+	PUNCT
ijassa-998	358	2	+	+	CCONJ
ijassa-998	358	3	ψ4	ψ4	NOUN
ijassa-998	358	4	(	(	PUNCT
ijassa-998	358	5	βt	βt	NOUN
ijassa-998	358	6	t	t	PROPN
ijassa-998	358	7	kt	kt	PROPN
ijassa-998	359	1	+	+	PROPN
ijassa-998	359	2	t	t	PROPN
ijassa-998	359	3	−	−	NOUN
ijassa-998	359	4	λdd	λdd	PROPN
ijassa-998	359	5	−	−	PROPN
ijassa-998	359	6	kdf	kdf	PROPN
ijassa-998	359	7	rd	rd	PROPN
ijassa-998	359	8	+	+	CCONJ
ijassa-998	359	9	kdr	kdr	PROPN
ijassa-998	359	10	a	a	PRON
ijassa-998	359	11	)	)	PUNCT
ijassa-998	359	12	+	+	PUNCT
ijassa-998	360	1	+	+	CCONJ
ijassa-998	360	2	ψ5	ψ5	NUM
ijassa-998	360	3	(	(	PUNCT
ijassa-998	360	4	f(ts)−	f(ts)−	ADV
ijassa-998	360	5	λtt	λtt	INTJ
ijassa-998	360	6	−	−	PROPN
ijassa-998	360	7	βt	βt	ADP
ijassa-998	360	8	t	t	PROPN
ijassa-998	360	9	kt	kt	PROPN
ijassa-998	360	10	+	+	PROPN
ijassa-998	360	11	t	t	PROPN
ijassa-998	360	12	−	−	PROPN
ijassa-998	360	13	ktf	ktf	PROPN
ijassa-998	360	14	rt	rt	PROPN
ijassa-998	361	1	+	+	CCONJ
ijassa-998	361	2	ktr	ktr	PROPN
ijassa-998	361	3	at	at	ADP
ijassa-998	361	4	)	)	PUNCT
ijassa-998	362	1	+	+	PUNCT
ijassa-998	363	1	+	+	CCONJ
ijassa-998	363	2	ψ6	ψ6	NOUN
ijassa-998	363	3	(	(	PUNCT
ijassa-998	363	4	−	−	PROPN
ijassa-998	363	5	λaa+	λaa+	PROPN
ijassa-998	363	6	kdf	kdf	PROPN
ijassa-998	363	7	rd	rd	PROPN
ijassa-998	363	8	−	−	PROPN
ijassa-998	363	9	kdr	kdr	PROPN
ijassa-998	363	10	a	a	PROPN
ijassa-998	363	11	)	)	PUNCT
ijassa-998	364	1	+	+	CCONJ
ijassa-998	364	2	ψ7(−λtat	ψ7(−λtat	PROPN
ijassa-998	364	3	+	+	CCONJ
ijassa-998	364	4	ktf	ktf	PROPN
ijassa-998	364	5	rt	rt	PROPN
ijassa-998	364	6	−	−	PROPN
ijassa-998	364	7	ktr	ktr	PROPN
ijassa-998	364	8	at	at	ADP
ijassa-998	364	9	)	)	PUNCT
ijassa-998	365	1	+	+	CCONJ
ijassa-998	365	2	+	+	X
ijassa-998	365	3	ψ7	ψ7	PROPN
ijassa-998	365	4	(	(	PUNCT
ijassa-998	365	5	−λatat(t	−λatat(t	NOUN
ijassa-998	365	6	)	)	PUNCT
ijassa-998	366	1	+	+	CCONJ
ijassa-998	366	2	ktf	ktf	PROPN
ijassa-998	366	3	r(t)t	r(t)t	PROPN
ijassa-998	366	4	(	(	PUNCT
ijassa-998	366	5	t)−	t)−	PROPN
ijassa-998	366	6	ktr	ktr	PROPN
ijassa-998	366	7	at(t	at(t	ADV
ijassa-998	366	8	)	)	PUNCT
ijassa-998	366	9	)	)	PUNCT
ijassa-998	367	1	+	+	PUNCT
ijassa-998	367	2	+	+	CCONJ
ijassa-998	367	3	ψ8	ψ8	ADJ
ijassa-998	367	4	(	(	PUNCT
ijassa-998	367	5	βp(a+	βp(a+	NOUN
ijassa-998	367	6	at	at	ADP
ijassa-998	367	7	+	+	CCONJ
ijassa-998	367	8	ϕ)−	ϕ)−	PROPN
ijassa-998	367	9	αppefrac	αppefrac	NOUN
ijassa-998	367	10	−	−	PROPN
ijassa-998	367	11	γpp	γpp	NOUN
ijassa-998	367	12	(	(	PUNCT
ijassa-998	367	13	n	n	X
ijassa-998	367	14	+	+	ADJ
ijassa-998	367	15	m)2	m)2	PROPN
ijassa-998	367	16	kp	kp	NOUN
ijassa-998	368	1	+	+	PROPN
ijassa-998	368	2	n	n	PROPN
ijassa-998	368	3	+	+	NOUN
ijassa-998	368	4	m	m	NOUN
ijassa-998	368	5	−	−	NOUN
ijassa-998	368	6	λpp	λpp	ADJ
ijassa-998	368	7	)	)	PUNCT
ijassa-998	369	1	+	+	CCONJ
ijassa-998	369	2	ψ9	ψ9	PROPN
ijassa-998	369	3	(	(	PUNCT
ijassa-998	369	4	−	−	PUNCT
ijassa-998	369	5	γh+	γh+	NOUN
ijassa-998	369	6	u	u	PROPN
ijassa-998	369	7	)	)	PUNCT
ijassa-998	369	8	the	the	DET
ijassa-998	369	9	optimal	optimal	ADJ
ijassa-998	369	10	control	control	NOUN
ijassa-998	369	11	law	law	NOUN
ijassa-998	369	12	is	be	AUX
ijassa-998	369	13	given	give	VERB
ijassa-998	369	14	as	as	ADP
ijassa-998	369	15	u∗(t	u∗(t	NOUN
ijassa-998	369	16	)	)	PUNCT
ijassa-998	369	17	=	=	SYM
ijassa-998	369	18	umax	umax	PROPN
ijassa-998	369	19	,	,	PUNCT
ijassa-998	369	20	ψ9(t	ψ9(t	PROPN
ijassa-998	369	21	)	)	PUNCT
ijassa-998	369	22	>	>	X
ijassa-998	369	23	0	0	NUM
ijassa-998	369	24	,	,	PUNCT
ijassa-998	369	25	0	0	NUM
ijassa-998	369	26	,	,	PUNCT
ijassa-998	369	27	ψ9(t	ψ9(t	NOUN
ijassa-998	369	28	)	)	PUNCT
ijassa-998	369	29	<	<	X
ijassa-998	369	30	0	0	NUM
ijassa-998	369	31	,	,	PUNCT
ijassa-998	369	32	us	us	PROPN
ijassa-998	369	33	∈	∈	PROPN
ijassa-998	369	34	(	(	PUNCT
ijassa-998	369	35	0	0	NUM
ijassa-998	369	36	,	,	PUNCT
ijassa-998	369	37	umax	umax	ADJ
ijassa-998	369	38	)	)	PUNCT
ijassa-998	369	39	,	,	PUNCT
ijassa-998	369	40	ψ9(t	ψ9(t	PROPN
ijassa-998	369	41	)	)	PUNCT
ijassa-998	369	42	=	=	SYM
ijassa-998	369	43	0	0	PUNCT
ijassa-998	370	1	∀t	∀t	PROPN
ijassa-998	370	2	∈	∈	PROPN
ijassa-998	370	3	(	(	PUNCT
ijassa-998	370	4	t1	t1	NOUN
ijassa-998	370	5	,	,	PUNCT
ijassa-998	370	6	t2	t2	NOUN
ijassa-998	370	7	)	)	PUNCT
ijassa-998	370	8	,	,	PUNCT
ijassa-998	370	9	(	(	PUNCT
ijassa-998	370	10	t1	t1	NOUN
ijassa-998	370	11	,	,	PUNCT
ijassa-998	370	12	t2	t2	PROPN
ijassa-998	370	13	)	)	PUNCT
ijassa-998	370	14	⊂	⊂	PROPN
ijassa-998	371	1	[	[	X
ijassa-998	371	2	0	0	NUM
ijassa-998	371	3	,	,	PUNCT
ijassa-998	371	4	t	t	X
ijassa-998	371	5	]	]	PUNCT
ijassa-998	371	6	,	,	PUNCT
ijassa-998	371	7	where	where	SCONJ
ijassa-998	371	8	ψ9(t	ψ9(t	VERB
ijassa-998	371	9	)	)	PUNCT
ijassa-998	371	10	is	be	AUX
ijassa-998	371	11	the	the	DET
ijassa-998	371	12	so	so	ADV
ijassa-998	371	13	called	call	VERB
ijassa-998	371	14	switching	switch	VERB
ijassa-998	371	15	function	function	NOUN
ijassa-998	371	16	.	.	PUNCT
ijassa-998	372	1	note	note	VERB
ijassa-998	372	2	,	,	PUNCT
ijassa-998	372	3	that	that	SCONJ
ijassa-998	372	4	the	the	DET
ijassa-998	372	5	optimal	optimal	ADJ
ijassa-998	372	6	control	control	NOUN
ijassa-998	372	7	function	function	NOUN
ijassa-998	372	8	u∗(t	u∗(t	NOUN
ijassa-998	372	9	)	)	PUNCT
ijassa-998	372	10	maximizes	maximize	VERB
ijassa-998	372	11	h	h	NOUN
ijassa-998	372	12	in	in	ADP
ijassa-998	372	13	all	all	DET
ijassa-998	372	14	points	point	NOUN
ijassa-998	372	15	t	t	PROPN
ijassa-998	372	16	∈	∈	PROPN
ijassa-998	373	1	[	[	X
ijassa-998	373	2	0	0	NUM
ijassa-998	373	3	,	,	PUNCT
ijassa-998	373	4	t	t	X
ijassa-998	373	5	]	]	PUNCT
ijassa-998	373	6	.	.	PUNCT
ijassa-998	374	1	copyright	copyright	NOUN
ijassa-998	374	2	c	c	ADP
ijassa-998	374	3	©	©	PROPN
ijassa-998	374	4	2020	2020	NUM
ijassa-998	374	5	assa	assa	NOUN
ijassa-998	374	6	.	.	PUNCT
ijassa-998	375	1	adv	adv	PROPN
ijassa-998	375	2	syst	syst	PROPN
ijassa-998	375	3	sci	sci	PROPN
ijassa-998	375	4	appl	appl	PROPN
ijassa-998	375	5	(	(	PUNCT
ijassa-998	375	6	2020	2020	NUM
ijassa-998	375	7	)	)	PUNCT
ijassa-998	375	8	on	on	ADP
ijassa-998	375	9	optimal	optimal	ADJ
ijassa-998	375	10	therapy	therapy	NOUN
ijassa-998	375	11	protocols	protocol	NOUN
ijassa-998	375	12	in	in	ADP
ijassa-998	375	13	the	the	DET
ijassa-998	375	14	math	math	NOUN
ijassa-998	375	15	.	.	PUNCT
ijassa-998	376	1	model	model	NOUN
ijassa-998	376	2	of	of	ADP
ijassa-998	376	3	prostate	prostate	NOUN
ijassa-998	376	4	cancer	cancer	NOUN
ijassa-998	376	5	progression103	progression103	PROPN
ijassa-998	376	6	from	from	ADP
ijassa-998	376	7	pontryagin	pontryagin	NOUN
ijassa-998	376	8	’s	’s	PART
ijassa-998	376	9	maximum	maximum	ADJ
ijassa-998	376	10	principle	principle	NOUN
ijassa-998	376	11	the	the	DET
ijassa-998	376	12	system	system	NOUN
ijassa-998	376	13	of	of	ADP
ijassa-998	376	14	adjoint	adjoint	NOUN
ijassa-998	376	15	variables	variable	NOUN
ijassa-998	376	16	is	be	AUX
ijassa-998	376	17	given	give	VERB
ijassa-998	376	18	by	by	ADP
ijassa-998	376	19	ψ̇1(t	ψ̇1(t	PROPN
ijassa-998	376	20	)	)	PUNCT
ijassa-998	377	1	=	=	SYM
ijassa-998	377	2	−∂h	−∂h	PROPN
ijassa-998	377	3	∂e	∂e	PROPN
ijassa-998	377	4	=	=	SYM
ijassa-998	377	5	−ψ1	−ψ1	PROPN
ijassa-998	377	6	(	(	PUNCT
ijassa-998	377	7	+	+	ADP
ijassa-998	377	8	µe(h(t))−	µe(h(t))−	ADJ
ijassa-998	377	9	2e(t)µe(h(t	2e(t)µe(h(t	NUM
ijassa-998	377	10	)	)	PUNCT
ijassa-998	377	11	)	)	PUNCT
ijassa-998	377	12	ηe	ηe	ADP
ijassa-998	377	13	−	−	PROPN
ijassa-998	377	14	εz(t	εz(t	NOUN
ijassa-998	377	15	)	)	PUNCT
ijassa-998	377	16	ηe	ηe	ADP
ijassa-998	377	17	−	−	PROPN
ijassa-998	377	18	δe	δe	NOUN
ijassa-998	377	19	)	)	PUNCT
ijassa-998	377	20	,	,	PUNCT
ijassa-998	377	21	(	(	PUNCT
ijassa-998	377	22	a.18	a.18	NOUN
ijassa-998	377	23	)	)	PUNCT
ijassa-998	377	24	ψ̇2(t	ψ̇2(t	PROPN
ijassa-998	377	25	)	)	PUNCT
ijassa-998	377	26	=	=	PUNCT
ijassa-998	378	1	−∂h	−∂h	NOUN
ijassa-998	378	2	∂z	∂z	PROPN
ijassa-998	378	3	=	=	PUNCT
ijassa-998	378	4	−ψ0	−ψ0	PROPN
ijassa-998	378	5	+	+	CCONJ
ijassa-998	378	6	ψ1	ψ1	PROPN
ijassa-998	378	7	e(t)ε	e(t)ε	PROPN
ijassa-998	378	8	ηe	ηe	ADP
ijassa-998	378	9	+	+	ADJ
ijassa-998	378	10	ψ2	ψ2	NOUN
ijassa-998	378	11	(	(	PUNCT
ijassa-998	378	12	−µ(h(t	−µ(h(t	PROPN
ijassa-998	378	13	)	)	PUNCT
ijassa-998	378	14	)	)	PUNCT
ijassa-998	379	1	+	+	CCONJ
ijassa-998	379	2	2µz(t	2µz(t	NUM
ijassa-998	379	3	)	)	PUNCT
ijassa-998	379	4	η	η	PROPN
ijassa-998	379	5	+	+	PROPN
ijassa-998	379	6	δ	δ	PROPN
ijassa-998	379	7	)	)	PUNCT
ijassa-998	379	8	,	,	PUNCT
ijassa-998	379	9	(	(	PUNCT
ijassa-998	379	10	a.19	a.19	NOUN
ijassa-998	379	11	)	)	PUNCT
ijassa-998	379	12	ψ̇9(t	ψ̇9(t	NOUN
ijassa-998	379	13	)	)	PUNCT
ijassa-998	379	14	=	=	SYM
ijassa-998	379	15	−∂h	−∂h	PROPN
ijassa-998	379	16	∂h	∂h	PROPN
ijassa-998	379	17	=	=	SYM
ijassa-998	379	18	−ψ1	−ψ1	PROPN
ijassa-998	379	19	dµe(h(t	dµe(h(t	PROPN
ijassa-998	379	20	)	)	PUNCT
ijassa-998	379	21	)	)	PUNCT
ijassa-998	379	22	dh(t	dh(t	NUM
ijassa-998	379	23	)	)	PUNCT
ijassa-998	379	24	e(t	e(t	PROPN
ijassa-998	379	25	)	)	PUNCT
ijassa-998	379	26	(	(	PUNCT
ijassa-998	379	27	1−	1−	NUM
ijassa-998	379	28	e(t	e(t	NOUN
ijassa-998	379	29	)	)	PUNCT
ijassa-998	379	30	ηe	ηe	ADP
ijassa-998	379	31	)	)	PUNCT
ijassa-998	379	32	−	−	PROPN
ijassa-998	379	33	ψ2	ψ2	NOUN
ijassa-998	379	34	dµ(h(t	dµ(h(t	NUM
ijassa-998	379	35	)	)	PUNCT
ijassa-998	379	36	)	)	PUNCT
ijassa-998	379	37	dh(t	dh(t	X
ijassa-998	379	38	)	)	PUNCT
ijassa-998	379	39	µz(t	µz(t	X
ijassa-998	379	40	)	)	PUNCT
ijassa-998	379	41	(	(	PUNCT
ijassa-998	379	42	1−	1−	NUM
ijassa-998	379	43	z(t	z(t	NOUN
ijassa-998	379	44	)	)	PUNCT
ijassa-998	379	45	η	η	PROPN
ijassa-998	379	46	)	)	PUNCT
ijassa-998	380	1	+	+	PUNCT
ijassa-998	381	1	+	+	ADV
ijassa-998	381	2	ψ9γ	ψ9γ	ADJ
ijassa-998	381	3	,	,	PUNCT
ijassa-998	381	4	ψ1(t	ψ1(t	X
ijassa-998	381	5	)	)	PUNCT
ijassa-998	382	1	=	=	SYM
ijassa-998	382	2	ψ2(t	ψ2(t	PROPN
ijassa-998	382	3	)	)	PUNCT
ijassa-998	382	4	=	=	SYM
ijassa-998	382	5	ψ9(t	ψ9(t	PROPN
ijassa-998	382	6	)	)	PUNCT
ijassa-998	382	7	=	=	SYM
ijassa-998	382	8	0	0	X
ijassa-998	382	9	.	.	PUNCT
ijassa-998	383	1	lemma	lemma	PROPN
ijassa-998	383	2	a.1	a.1	PROPN
ijassa-998	383	3	:	:	PUNCT
ijassa-998	383	4	in	in	ADP
ijassa-998	383	5	the	the	DET
ijassa-998	383	6	optimal	optimal	ADJ
ijassa-998	383	7	control	control	NOUN
ijassa-998	383	8	problem	problem	NOUN
ijassa-998	383	9	(	(	PUNCT
ijassa-998	383	10	3.4	3.4	NUM
ijassa-998	383	11	)	)	PUNCT
ijassa-998	383	12	holds	hold	VERB
ijassa-998	383	13	ψ0	ψ0	ADJ
ijassa-998	383	14	=	=	SYM
ijassa-998	383	15	−1	−1	NOUN
ijassa-998	383	16	.	.	PUNCT
ijassa-998	384	1	proof	proof	NOUN
ijassa-998	384	2	from	from	ADP
ijassa-998	384	3	ψi(t	ψi(t	NOUN
ijassa-998	384	4	)	)	PUNCT
ijassa-998	384	5	=	=	SYM
ijassa-998	384	6	0	0	NUM
ijassa-998	384	7	,	,	PUNCT
ijassa-998	384	8	1	1	NUM
ijassa-998	384	9	≤	≤	NUM
ijassa-998	384	10	i	i	PRON
ijassa-998	384	11	≤	≤	ADV
ijassa-998	384	12	9	9	NUM
ijassa-998	384	13	,	,	PUNCT
ijassa-998	384	14	and	and	CCONJ
ijassa-998	384	15	the	the	DET
ijassa-998	384	16	condition	condition	NOUN
ijassa-998	384	17	(	(	PUNCT
ijassa-998	384	18	ψ0	ψ0	ADJ
ijassa-998	384	19	,	,	PUNCT
ijassa-998	384	20	ψ1	ψ1	ADJ
ijassa-998	384	21	,	,	PUNCT
ijassa-998	384	22	...	...	PUNCT
ijassa-998	384	23	,	,	PUNCT
ijassa-998	384	24	ψ9	ψ9	PROPN
ijassa-998	384	25	)	)	PUNCT
ijassa-998	384	26	6=	6=	ADP
ijassa-998	384	27	0	0	NUM
ijassa-998	384	28	follows	follow	VERB
ijassa-998	384	29	that	that	SCONJ
ijassa-998	384	30	ψ0	ψ0	ADJ
ijassa-998	384	31	=	=	SYM
ijassa-998	384	32	−1	−1	NOUN
ijassa-998	384	33	.	.	PUNCT
ijassa-998	385	1	from	from	ADP
ijassa-998	385	2	lemma	lemma	PROPN
ijassa-998	385	3	a.1	a.1	PROPN
ijassa-998	385	4	follows	follow	VERB
ijassa-998	385	5	ψ1(t	ψ1(t	PART
ijassa-998	385	6	)	)	PUNCT
ijassa-998	385	7	=	=	SYM
ijassa-998	385	8	0	0	PUNCT
ijassa-998	385	9	∀t	∀t	PROPN
ijassa-998	385	10	∈	∈	X
ijassa-998	386	1	[	[	X
ijassa-998	386	2	0	0	NUM
ijassa-998	386	3	,	,	PUNCT
ijassa-998	386	4	t	t	X
ijassa-998	386	5	]	]	PUNCT
ijassa-998	386	6	,	,	PUNCT
ijassa-998	386	7	ψ2(t	ψ2(t	PROPN
ijassa-998	386	8	)	)	PUNCT
ijassa-998	386	9	=	=	SYM
ijassa-998	386	10	ew2(t	ew2(t	PROPN
ijassa-998	386	11	)	)	PUNCT
ijassa-998	386	12	(	(	PUNCT
ijassa-998	386	13	∫	∫	PROPN
ijassa-998	386	14	t	t	PROPN
ijassa-998	386	15	0	0	NUM
ijassa-998	386	16	e−w2(s)ds−	e−w2(s)ds−	PROPN
ijassa-998	386	17	∫	∫	PROPN
ijassa-998	386	18	t	t	NOUN
ijassa-998	386	19	0	0	NUM
ijassa-998	386	20	e−w2(t)dt	e−w2(t)dt	PROPN
ijassa-998	386	21	)	)	PUNCT
ijassa-998	386	22	,	,	PUNCT
ijassa-998	386	23	ψ9(t	ψ9(t	PROPN
ijassa-998	386	24	)	)	PUNCT
ijassa-998	386	25	=	=	SYM
ijassa-998	386	26	eγt[−	eγt[−	PROPN
ijassa-998	386	27	∫	∫	PROPN
ijassa-998	386	28	t	t	PROPN
ijassa-998	386	29	0	0	NUM
ijassa-998	386	30	e−γsψ2(s	e−γsψ2(s	NOUN
ijassa-998	386	31	)	)	PUNCT
ijassa-998	386	32	dµ(h(s	dµ(h(	NOUN
ijassa-998	386	33	)	)	PUNCT
ijassa-998	386	34	)	)	PUNCT
ijassa-998	387	1	dh(s	dh(s	X
ijassa-998	387	2	)	)	PUNCT
ijassa-998	387	3	z(s	z(s	NOUN
ijassa-998	387	4	)	)	PUNCT
ijassa-998	387	5	(	(	PUNCT
ijassa-998	387	6	1−	1−	NUM
ijassa-998	387	7	z(s	z(s	PROPN
ijassa-998	387	8	)	)	PUNCT
ijassa-998	387	9	η	η	PROPN
ijassa-998	387	10	)	)	PUNCT
ijassa-998	387	11	ds+	ds+	PROPN
ijassa-998	388	1	+	+	CCONJ
ijassa-998	388	2	∫	∫	PROPN
ijassa-998	388	3	t	t	PROPN
ijassa-998	388	4	0	0	NUM
ijassa-998	388	5	e−γtψ2(t	e−γtψ2(t	NOUN
ijassa-998	388	6	)	)	PUNCT
ijassa-998	388	7	dµ(h(t	dµ(h(t	NOUN
ijassa-998	388	8	)	)	PUNCT
ijassa-998	388	9	)	)	PUNCT
ijassa-998	388	10	dh(t	dh(t	NUM
ijassa-998	388	11	)	)	PUNCT
ijassa-998	388	12	z(t	z(t	NOUN
ijassa-998	388	13	)	)	PUNCT
ijassa-998	388	14	(	(	PUNCT
ijassa-998	388	15	1−	1−	NUM
ijassa-998	388	16	z(t	z(t	NOUN
ijassa-998	388	17	)	)	PUNCT
ijassa-998	388	18	η	η	PROPN
ijassa-998	388	19	)	)	PUNCT
ijassa-998	388	20	dt	dt	X
ijassa-998	389	1	]	]	X
ijassa-998	389	2	,	,	PUNCT
ijassa-998	389	3	where	where	SCONJ
ijassa-998	389	4	w2(t	w2(t	NOUN
ijassa-998	389	5	)	)	PUNCT
ijassa-998	389	6	=	=	SYM
ijassa-998	390	1	∫	∫	PROPN
ijassa-998	390	2	t	t	PROPN
ijassa-998	390	3	0	0	NUM
ijassa-998	390	4	(	(	PUNCT
ijassa-998	390	5	−µ(h(s	−µ(h(s	PROPN
ijassa-998	390	6	)	)	PUNCT
ijassa-998	390	7	)	)	PUNCT
ijassa-998	391	1	+	+	CCONJ
ijassa-998	391	2	2µ(h(s))z(s	2µ(h(s))z(s	X
ijassa-998	391	3	)	)	PUNCT
ijassa-998	391	4	η	η	PROPN
ijassa-998	391	5	+	+	PROPN
ijassa-998	391	6	δ	δ	PROPN
ijassa-998	391	7	)	)	PUNCT
ijassa-998	391	8	ds	ds	PROPN
ijassa-998	391	9	.	.	PUNCT
ijassa-998	391	10	ψ9(t	ψ9(t	PART
ijassa-998	391	11	)	)	PUNCT
ijassa-998	391	12	depends	depend	VERB
ijassa-998	391	13	on	on	ADP
ijassa-998	391	14	ψ2(t	ψ2(t	PROPN
ijassa-998	391	15	)	)	PUNCT
ijassa-998	391	16	and	and	CCONJ
ijassa-998	391	17	therefore	therefore	ADV
ijassa-998	391	18	this	this	DET
ijassa-998	391	19	function	function	NOUN
ijassa-998	391	20	is	be	AUX
ijassa-998	391	21	analysed	analyse	VERB
ijassa-998	391	22	for	for	ADP
ijassa-998	391	23	the	the	DET
ijassa-998	391	24	mathematical	mathematical	ADJ
ijassa-998	391	25	solution	solution	NOUN
ijassa-998	391	26	of	of	ADP
ijassa-998	391	27	this	this	DET
ijassa-998	391	28	problem	problem	NOUN
ijassa-998	391	29	.	.	PUNCT
ijassa-998	392	1	note	note	NOUN
ijassa-998	392	2	,	,	PUNCT
ijassa-998	392	3	that	that	PRON
ijassa-998	392	4	ψ9(t	ψ9(t	VERB
ijassa-998	392	5	)	)	PUNCT
ijassa-998	392	6	also	also	ADV
ijassa-998	392	7	depends	depend	VERB
ijassa-998	392	8	on	on	ADP
ijassa-998	392	9	ψ1(t	ψ1(t	NOUN
ijassa-998	392	10	)	)	PUNCT
ijassa-998	392	11	but	but	CCONJ
ijassa-998	392	12	as	as	SCONJ
ijassa-998	392	13	shown	show	VERB
ijassa-998	392	14	before	before	ADP
ijassa-998	392	15	ψ1(t	ψ1(t	PROPN
ijassa-998	392	16	)	)	PUNCT
ijassa-998	392	17	≡	≡	PROPN
ijassa-998	392	18	0	0	PUNCT
ijassa-998	392	19	.	.	PUNCT
ijassa-998	393	1	proof	proof	NOUN
ijassa-998	393	2	of	of	ADP
ijassa-998	393	3	theorem	theorem	ADJ
ijassa-998	393	4	5.1	5.1	NUM
ijassa-998	393	5	lemma	lemma	PROPN
ijassa-998	393	6	a.2	a.2	NOUN
ijassa-998	393	7	:	:	PUNCT
ijassa-998	393	8	ψ2(t	ψ2(t	PROPN
ijassa-998	393	9	)	)	PUNCT
ijassa-998	393	10	is	be	AUX
ijassa-998	393	11	a	a	DET
ijassa-998	393	12	negative	negative	ADJ
ijassa-998	393	13	monotone	monotone	ADJ
ijassa-998	393	14	increasing	increase	VERB
ijassa-998	393	15	function	function	NOUN
ijassa-998	393	16	on	on	ADP
ijassa-998	393	17	[	[	X
ijassa-998	393	18	0	0	NUM
ijassa-998	393	19	,	,	PUNCT
ijassa-998	393	20	t	t	X
ijassa-998	393	21	]	]	PUNCT
ijassa-998	393	22	.	.	PUNCT
ijassa-998	394	1	proof	proof	NOUN
ijassa-998	394	2	in	in	ADP
ijassa-998	394	3	order	order	NOUN
ijassa-998	394	4	to	to	PART
ijassa-998	394	5	analyse	analyse	VERB
ijassa-998	394	6	the	the	DET
ijassa-998	394	7	behaviour	behaviour	NOUN
ijassa-998	394	8	of	of	ADP
ijassa-998	394	9	ψ2(t	ψ2(t	PROPN
ijassa-998	394	10	)	)	PUNCT
ijassa-998	394	11	the	the	DET
ijassa-998	394	12	auxiliary	auxiliary	ADJ
ijassa-998	394	13	function	function	NOUN
ijassa-998	394	14	ψ̃2	ψ̃2	PROPN
ijassa-998	394	15	=	=	SYM
ijassa-998	394	16	e−w2(t)ψ2(t	e−w2(t)ψ2(t	NOUN
ijassa-998	394	17	)	)	PUNCT
ijassa-998	394	18	which	which	PRON
ijassa-998	394	19	has	have	VERB
ijassa-998	394	20	the	the	DET
ijassa-998	394	21	same	same	ADJ
ijassa-998	394	22	sign	sign	NOUN
ijassa-998	394	23	and	and	CCONJ
ijassa-998	394	24	zeros	zero	NOUN
ijassa-998	394	25	as	as	ADP
ijassa-998	394	26	ψ2(t	ψ2(t	PROPN
ijassa-998	394	27	)	)	PUNCT
ijassa-998	394	28	is	be	AUX
ijassa-998	394	29	used	use	VERB
ijassa-998	394	30	.	.	PUNCT
ijassa-998	395	1	it	it	PRON
ijassa-998	395	2	holds	hold	VERB
ijassa-998	395	3	ψ̃2(t	ψ̃2(t	PROPN
ijassa-998	395	4	)	)	PUNCT
ijassa-998	395	5	<	<	X
ijassa-998	395	6	0	0	NUM
ijassa-998	395	7	,	,	PUNCT
ijassa-998	395	8	t	t	PROPN
ijassa-998	395	9	∈	∈	PROPN
ijassa-998	396	1	[	[	X
ijassa-998	396	2	0	0	NUM
ijassa-998	396	3	,	,	PUNCT
ijassa-998	396	4	t	t	PROPN
ijassa-998	396	5	)	)	PUNCT
ijassa-998	396	6	due	due	ADP
ijassa-998	396	7	to	to	ADP
ijassa-998	396	8	t∫	t∫	PRON
ijassa-998	396	9	0	0	NUM
ijassa-998	396	10	e−w2(t)dt	e−w2(t)dt	PROPN
ijassa-998	396	11	>	>	X
ijassa-998	396	12	t∫	t∫	PROPN
ijassa-998	396	13	0	0	PUNCT
ijassa-998	396	14	e−w2(s)ds	e−w2(s)ds	PROPN
ijassa-998	396	15	∀t	∀t	PROPN
ijassa-998	396	16	∈	∈	PROPN
ijassa-998	396	17	[	[	X
ijassa-998	396	18	0	0	NUM
ijassa-998	396	19	,	,	PUNCT
ijassa-998	396	20	t	t	NOUN
ijassa-998	396	21	)	)	PUNCT
ijassa-998	396	22	and	and	CCONJ
ijassa-998	396	23	ψ̃2(t	ψ̃2(t	PROPN
ijassa-998	396	24	)	)	PUNCT
ijassa-998	397	1	=	=	PUNCT
ijassa-998	397	2	0	0	X
ijassa-998	397	3	.	.	PUNCT
ijassa-998	398	1	copyright	copyright	NOUN
ijassa-998	398	2	c	c	ADP
ijassa-998	398	3	©	©	PROPN
ijassa-998	398	4	2020	2020	NUM
ijassa-998	398	5	assa	assa	NOUN
ijassa-998	398	6	.	.	PUNCT
ijassa-998	399	1	adv	adv	PROPN
ijassa-998	399	2	syst	syst	PROPN
ijassa-998	399	3	sci	sci	PROPN
ijassa-998	399	4	appl	appl	PROPN
ijassa-998	399	5	(	(	PUNCT
ijassa-998	399	6	2020	2020	NUM
ijassa-998	399	7	)	)	PUNCT
ijassa-998	399	8	104	104	NUM
ijassa-998	399	9	m.-c	m.-c	NOUN
ijassa-998	399	10	.	.	PUNCT
ijassa-998	400	1	litzinger	litzinger	NOUN
ijassa-998	400	2	,	,	PUNCT
ijassa-998	400	3	y.	y.	PROPN
ijassa-998	400	4	todorov	todorov	PROPN
ijassa-998	400	5	,	,	PUNCT
ijassa-998	400	6	m.	m.	NOUN
ijassa-998	400	7	föller	föller	PROPN
ijassa-998	400	8	-	-	PUNCT
ijassa-998	400	9	nord	nord	PROPN
ijassa-998	400	10	,	,	PUNCT
ijassa-998	400	11	m.k	m.k	PROPN
ijassa-998	400	12	.	.	PUNCT
ijassa-998	400	13	chaudhary	chaudhary	PROPN
ijassa-998	400	14	,	,	PUNCT
ijassa-998	400	15	a.s	a.s	PROPN
ijassa-998	400	16	.	.	PROPN
ijassa-998	400	17	bratus	bratus	PROPN
ijassa-998	400	18	because	because	SCONJ
ijassa-998	400	19	t∫	t∫	PRON
ijassa-998	400	20	0	0	NUM
ijassa-998	400	21	ew2(s)ds	ew2(s)ds	NOUN
ijassa-998	400	22	is	be	AUX
ijassa-998	400	23	a	a	DET
ijassa-998	400	24	strictly	strictly	ADV
ijassa-998	400	25	increasing	increase	VERB
ijassa-998	400	26	function	function	NOUN
ijassa-998	400	27	ψ̃2(t	ψ̃2(t	PROPN
ijassa-998	400	28	)	)	PUNCT
ijassa-998	400	29	has	have	VERB
ijassa-998	400	30	no	no	DET
ijassa-998	400	31	zeros	zero	NOUN
ijassa-998	400	32	on	on	ADP
ijassa-998	400	33	[	[	X
ijassa-998	400	34	0	0	NUM
ijassa-998	400	35	,	,	PUNCT
ijassa-998	400	36	t	t	NOUN
ijassa-998	400	37	)	)	PUNCT
ijassa-998	400	38	and	and	CCONJ
ijassa-998	400	39	therefore	therefore	ADV
ijassa-998	400	40	ψ2(t	ψ2(t	PROPN
ijassa-998	400	41	)	)	PUNCT
ijassa-998	400	42	is	be	AUX
ijassa-998	400	43	a	a	DET
ijassa-998	400	44	negative	negative	ADJ
ijassa-998	400	45	monotone	monotone	ADJ
ijassa-998	400	46	increasing	increase	VERB
ijassa-998	400	47	function	function	NOUN
ijassa-998	400	48	with	with	ADP
ijassa-998	400	49	ψ2(t	ψ2(t	PROPN
ijassa-998	400	50	)	)	PUNCT
ijassa-998	400	51	≤	≤	NOUN
ijassa-998	401	1	0	0	NUM
ijassa-998	402	1	∀t	∀t	PROPN
ijassa-998	402	2	∈	∈	PROPN
ijassa-998	403	1	[	[	X
ijassa-998	403	2	0	0	NUM
ijassa-998	403	3	,	,	PUNCT
ijassa-998	403	4	t	t	X
ijassa-998	403	5	]	]	PUNCT
ijassa-998	403	6	.	.	PUNCT
ijassa-998	404	1	lemma	lemma	PROPN
ijassa-998	404	2	a.3	a.3	PROPN
ijassa-998	404	3	:	:	PUNCT
ijassa-998	404	4	ψ9(t	ψ9(t	NUM
ijassa-998	404	5	)	)	PUNCT
ijassa-998	404	6	is	be	AUX
ijassa-998	404	7	a	a	DET
ijassa-998	404	8	positive	positive	ADJ
ijassa-998	404	9	decreasing	decrease	VERB
ijassa-998	404	10	function	function	NOUN
ijassa-998	404	11	on	on	ADP
ijassa-998	404	12	[	[	X
ijassa-998	404	13	0	0	NUM
ijassa-998	404	14	,	,	PUNCT
ijassa-998	404	15	t	t	X
ijassa-998	404	16	]	]	PUNCT
ijassa-998	404	17	.	.	PUNCT
ijassa-998	405	1	proof	proof	NOUN
ijassa-998	405	2	from	from	ADP
ijassa-998	405	3	ψ9(t	ψ9(t	PROPN
ijassa-998	405	4	)	)	PUNCT
ijassa-998	405	5	=	=	SYM
ijassa-998	405	6	eγt	eγt	NOUN
ijassa-998	405	7	(	(	PUNCT
ijassa-998	405	8	ψ90	ψ90	PROPN
ijassa-998	405	9	−	−	PROPN
ijassa-998	405	10	∫	∫	PROPN
ijassa-998	405	11	t	t	PROPN
ijassa-998	405	12	0	0	NUM
ijassa-998	405	13	e−γsψ2(s	e−γsψ2(s	PROPN
ijassa-998	405	14	)	)	PUNCT
ijassa-998	405	15	µ(h(s	µ(h(s	PROPN
ijassa-998	405	16	)	)	PUNCT
ijassa-998	405	17	)	)	PUNCT
ijassa-998	405	18	dh(s	dh(s	X
ijassa-998	405	19	)	)	PUNCT
ijassa-998	405	20	z(s	z(s	NOUN
ijassa-998	405	21	)	)	PUNCT
ijassa-998	405	22	(	(	PUNCT
ijassa-998	405	23	1−	1−	NUM
ijassa-998	405	24	z(s	z(s	PROPN
ijassa-998	405	25	)	)	PUNCT
ijassa-998	405	26	η	η	PROPN
ijassa-998	405	27	)	)	PUNCT
ijassa-998	405	28	ds	ds	PROPN
ijassa-998	405	29	)	)	PUNCT
ijassa-998	405	30	and	and	CCONJ
ijassa-998	405	31	ψ9(t	ψ9(t	PART
ijassa-998	405	32	)	)	PUNCT
ijassa-998	405	33	=	=	SYM
ijassa-998	405	34	0	0	NUM
ijassa-998	405	35	ψ90	ψ90	NOUN
ijassa-998	405	36	=	=	SYM
ijassa-998	405	37	∫	∫	PROPN
ijassa-998	405	38	t	t	PROPN
ijassa-998	405	39	0	0	NUM
ijassa-998	405	40	e−γtψ2(t	e−γtψ2(t	NOUN
ijassa-998	405	41	)	)	PUNCT
ijassa-998	405	42	µ(h(t	µ(h(t	PROPN
ijassa-998	405	43	)	)	PUNCT
ijassa-998	405	44	)	)	PUNCT
ijassa-998	405	45	dh(t	dh(t	X
ijassa-998	405	46	)	)	PUNCT
ijassa-998	405	47	z(t	z(t	NOUN
ijassa-998	405	48	)	)	PUNCT
ijassa-998	405	49	(	(	PUNCT
ijassa-998	405	50	1−	1−	NUM
ijassa-998	405	51	z(t	z(t	NOUN
ijassa-998	405	52	)	)	PUNCT
ijassa-998	405	53	η	η	PROPN
ijassa-998	405	54	)	)	PUNCT
ijassa-998	405	55	dt	dt	PROPN
ijassa-998	405	56	from	from	ADP
ijassa-998	405	57	the	the	DET
ijassa-998	405	58	definition	definition	NOUN
ijassa-998	405	59	of	of	ADP
ijassa-998	405	60	the	the	DET
ijassa-998	405	61	given	give	VERB
ijassa-998	405	62	problem	problem	NOUN
ijassa-998	405	63	follows	follow	VERB
ijassa-998	405	64	z(t	z(t	NOUN
ijassa-998	405	65	)	)	PUNCT
ijassa-998	405	66	≥	≥	NOUN
ijassa-998	405	67	0	0	NUM
ijassa-998	405	68	∀t	∀t	PROPN
ijassa-998	405	69	∈	∈	X
ijassa-998	406	1	[	[	X
ijassa-998	406	2	0	0	NUM
ijassa-998	406	3	,	,	PUNCT
ijassa-998	406	4	t	t	NOUN
ijassa-998	406	5	]	]	PUNCT
ijassa-998	406	6	and	and	CCONJ
ijassa-998	406	7	(	(	PUNCT
ijassa-998	406	8	1−	1−	NUM
ijassa-998	406	9	z(t	z(t	NOUN
ijassa-998	406	10	)	)	PUNCT
ijassa-998	406	11	η	η	PROPN
ijassa-998	406	12	)	)	PUNCT
ijassa-998	406	13	∈	∈	PROPN
ijassa-998	406	14	(	(	PUNCT
ijassa-998	406	15	0	0	NUM
ijassa-998	406	16	,	,	PUNCT
ijassa-998	406	17	1	1	NUM
ijassa-998	406	18	)	)	PUNCT
ijassa-998	406	19	.	.	PUNCT
ijassa-998	407	1	moreover	moreover	ADV
ijassa-998	407	2	it	it	PRON
ijassa-998	407	3	holds	hold	VERB
ijassa-998	407	4	ψ2	ψ2	NOUN
ijassa-998	407	5	≤	≤	NUM
ijassa-998	407	6	0	0	NUM
ijassa-998	407	7	and	and	CCONJ
ijassa-998	407	8	dµ(h	dµ(h	NOUN
ijassa-998	407	9	)	)	PUNCT
ijassa-998	408	1	dh	dh	NOUN
ijassa-998	408	2	<	<	X
ijassa-998	408	3	0	0	PUNCT
ijassa-998	408	4	∀t	∀t	PROPN
ijassa-998	408	5	∈	∈	PROPN
ijassa-998	409	1	[	[	X
ijassa-998	409	2	0	0	NUM
ijassa-998	409	3	,	,	PUNCT
ijassa-998	409	4	t	t	X
ijassa-998	409	5	]	]	PUNCT
ijassa-998	409	6	.	.	PUNCT
ijassa-998	410	1	therefore	therefore	ADV
ijassa-998	410	2	it	it	PRON
ijassa-998	410	3	follows∫	follows∫	VERB
ijassa-998	410	4	t	t	NOUN
ijassa-998	410	5	0	0	NUM
ijassa-998	410	6	e−γtψ2(t	e−γtψ2(t	NOUN
ijassa-998	410	7	)	)	PUNCT
ijassa-998	410	8	dµ(h(t	dµ(h(t	NOUN
ijassa-998	410	9	)	)	PUNCT
ijassa-998	410	10	)	)	PUNCT
ijassa-998	410	11	dh(t	dh(t	NUM
ijassa-998	410	12	)	)	PUNCT
ijassa-998	410	13	z(t	z(t	NOUN
ijassa-998	410	14	)	)	PUNCT
ijassa-998	410	15	(	(	PUNCT
ijassa-998	410	16	1−	1−	NUM
ijassa-998	410	17	z(t	z(t	NOUN
ijassa-998	410	18	)	)	PUNCT
ijassa-998	410	19	η	η	PROPN
ijassa-998	410	20	)	)	PUNCT
ijassa-998	411	1	dt	dt	X
ijassa-998	411	2	>	>	X
ijassa-998	411	3	∫	∫	PROPN
ijassa-998	411	4	t	t	PROPN
ijassa-998	411	5	0	0	NUM
ijassa-998	411	6	e−γsψ2(s	e−γsψ2(s	NOUN
ijassa-998	411	7	)	)	PUNCT
ijassa-998	411	8	dµ(h(s	dµ(h(	NOUN
ijassa-998	411	9	)	)	PUNCT
ijassa-998	411	10	)	)	PUNCT
ijassa-998	412	1	dh(s	dh(s	X
ijassa-998	412	2	)	)	PUNCT
ijassa-998	412	3	z(s	z(s	NOUN
ijassa-998	412	4	)	)	PUNCT
ijassa-998	412	5	(	(	PUNCT
ijassa-998	412	6	1−	1−	NUM
ijassa-998	412	7	z(s	z(s	PROPN
ijassa-998	412	8	)	)	PUNCT
ijassa-998	412	9	η	η	PROPN
ijassa-998	412	10	)	)	PUNCT
ijassa-998	412	11	ds	ds	ADJ
ijassa-998	412	12	∀t	∀t	PROPN
ijassa-998	412	13	∈	∈	PROPN
ijassa-998	413	1	[	[	X
ijassa-998	413	2	0	0	NUM
ijassa-998	413	3	,	,	PUNCT
ijassa-998	413	4	t	t	X
ijassa-998	413	5	]	]	PUNCT
ijassa-998	413	6	.	.	PUNCT
ijassa-998	414	1	thus	thus	ADV
ijassa-998	414	2	ψ9(t	ψ9(t	VERB
ijassa-998	414	3	)	)	PUNCT
ijassa-998	414	4	>	>	X
ijassa-998	414	5	0	0	PUNCT
ijassa-998	414	6	∀t	∀t	PROPN
ijassa-998	414	7	∈	∈	X
ijassa-998	415	1	[	[	X
ijassa-998	415	2	0	0	NUM
ijassa-998	415	3	,	,	PUNCT
ijassa-998	415	4	t	t	NOUN
ijassa-998	415	5	)	)	PUNCT
ijassa-998	415	6	and	and	CCONJ
ijassa-998	415	7	u∗(t	u∗(t	NOUN
ijassa-998	415	8	)	)	PUNCT
ijassa-998	415	9	=	=	PUNCT
ijassa-998	415	10	umax	umax	PROPN
ijassa-998	415	11	.	.	PUNCT
ijassa-998	416	1	a.4	a.4	X
ijassa-998	416	2	.	.	PUNCT
ijassa-998	417	1	proof	proof	NOUN
ijassa-998	417	2	of	of	ADP
ijassa-998	417	3	the	the	DET
ijassa-998	417	4	statement	statement	NOUN
ijassa-998	417	5	proof	proof	NOUN
ijassa-998	417	6	from	from	ADP
ijassa-998	417	7	theorem	theorem	ADJ
ijassa-998	417	8	5.1	5.1	NUM
ijassa-998	417	9	follows	follow	VERB
ijassa-998	417	10	u∗(t	u∗(t	NOUN
ijassa-998	417	11	)	)	PUNCT
ijassa-998	417	12	=	=	PUNCT
ijassa-998	418	1	umax	umax	ADJ
ijassa-998	418	2	for	for	ADP
ijassa-998	418	3	t	t	PROPN
ijassa-998	418	4	∈	∈	PROPN
ijassa-998	419	1	[	[	X
ijassa-998	419	2	0	0	NUM
ijassa-998	419	3	,	,	PUNCT
ijassa-998	419	4	tj	tj	NOUN
ijassa-998	419	5	)	)	PUNCT
ijassa-998	419	6	.	.	PUNCT
ijassa-998	420	1	because	because	SCONJ
ijassa-998	420	2	of	of	ADP
ijassa-998	420	3	the	the	DET
ijassa-998	420	4	minimization	minimization	NOUN
ijassa-998	420	5	of	of	ADP
ijassa-998	420	6	the	the	DET
ijassa-998	420	7	objective	objective	ADJ
ijassa-998	420	8	function	function	NOUN
ijassa-998	420	9	(	(	PUNCT
ijassa-998	420	10	3.3	3.3	NUM
ijassa-998	420	11	)	)	PUNCT
ijassa-998	420	12	the	the	DET
ijassa-998	420	13	maximal	maximal	ADJ
ijassa-998	420	14	admissible	admissible	ADJ
ijassa-998	420	15	value	value	NOUN
ijassa-998	420	16	of	of	ADP
ijassa-998	420	17	u	u	NOUN
ijassa-998	420	18	on	on	ADP
ijassa-998	420	19	the	the	DET
ijassa-998	420	20	constraint	constraint	NOUN
ijassa-998	420	21	boundary	boundary	NOUN
ijassa-998	420	22	has	have	VERB
ijassa-998	420	23	to	to	PART
ijassa-998	420	24	be	be	AUX
ijassa-998	420	25	chosen	choose	VERB
ijassa-998	420	26	.	.	PUNCT
ijassa-998	421	1	the	the	DET
ijassa-998	421	2	limit	limit	NOUN
ijassa-998	421	3	of	of	ADP
ijassa-998	421	4	this	this	DET
ijassa-998	421	5	value	value	NOUN
ijassa-998	421	6	is	be	AUX
ijassa-998	421	7	given	give	VERB
ijassa-998	421	8	by	by	ADP
ijassa-998	421	9	u(t	u(t	NOUN
ijassa-998	421	10	)	)	PUNCT
ijassa-998	421	11	=	=	PUNCT
ijassa-998	421	12	(	(	PUNCT
ijassa-998	421	13	1−	1−	NUM
ijassa-998	421	14	εz(tj	εz(tj	PROPN
ijassa-998	421	15	)	)	PUNCT
ijassa-998	422	1	+	+	CCONJ
ijassa-998	422	2	δeηe	δeηe	X
ijassa-998	422	3	(	(	PUNCT
ijassa-998	422	4	ηe	ηe	ADP
ijassa-998	422	5	−	−	PROPN
ijassa-998	422	6	ec)µ0	ec)µ0	PROPN
ijassa-998	422	7	e	e	PROPN
ijassa-998	422	8	)	)	PUNCT
ijassa-998	422	9	ke	ke	NOUN
ijassa-998	422	10	−	−	PROPN
ijassa-998	423	1	(	(	PUNCT
ijassa-998	423	2	1−	1−	NUM
ijassa-998	423	3	εz(tj	εz(tj	PROPN
ijassa-998	423	4	)	)	PUNCT
ijassa-998	424	1	+	+	CCONJ
ijassa-998	424	2	δeηe	δeηe	X
ijassa-998	424	3	(	(	PUNCT
ijassa-998	424	4	ηe	ηe	ADP
ijassa-998	424	5	−	−	PROPN
ijassa-998	424	6	ec)µ0	ec)µ0	PROPN
ijassa-998	424	7	e	e	PROPN
ijassa-998	424	8	)	)	PUNCT
ijassa-998	424	9	,	,	PUNCT
ijassa-998	424	10	t	t	PROPN
ijassa-998	424	11	∈	∈	PROPN
ijassa-998	425	1	[	[	X
ijassa-998	425	2	tj	tj	X
ijassa-998	425	3	,	,	PUNCT
ijassa-998	425	4	t	t	X
ijassa-998	425	5	]	]	PUNCT
ijassa-998	425	6	.	.	PUNCT
ijassa-998	426	1	copyright	copyright	NOUN
ijassa-998	426	2	c	c	ADP
ijassa-998	426	3	©	©	PROPN
ijassa-998	426	4	2020	2020	NUM
ijassa-998	426	5	assa	assa	NOUN
ijassa-998	426	6	.	.	PUNCT
ijassa-998	427	1	adv	adv	PROPN
ijassa-998	427	2	syst	syst	PROPN
ijassa-998	427	3	sci	sci	PROPN
ijassa-998	427	4	appl	appl	PROPN
ijassa-998	427	5	(	(	PUNCT
ijassa-998	427	6	2020	2020	NUM
ijassa-998	427	7	)	)	PUNCT
ijassa-998	427	8	introduction	introduction	NOUN
ijassa-998	427	9	mathematical	mathematical	ADJ
ijassa-998	427	10	model	model	NOUN
ijassa-998	427	11	of	of	ADP
ijassa-998	427	12	prostate	prostate	NOUN
ijassa-998	427	13	cancer	cancer	NOUN
ijassa-998	427	14	an	an	DET
ijassa-998	427	15	alternative	alternative	NOUN
ijassa-998	427	16	therapy	therapy	NOUN
ijassa-998	427	17	strategy	strategy	NOUN
ijassa-998	427	18	suboptimal	suboptimal	ADJ
ijassa-998	427	19	therapy	therapy	NOUN
ijassa-998	427	20	strategy	strategy	NOUN
ijassa-998	427	21	optimal	optimal	ADJ
ijassa-998	427	22	therapy	therapy	NOUN
ijassa-998	427	23	strategy	strategy	NOUN
ijassa-998	427	24	summary	summary	NOUN
ijassa-998	427	25	appendixes	appendix	NOUN
ijassa-998	427	26	model	model	PROPN
ijassa-998	427	27	parameter	parameter	PROPN
ijassa-998	427	28	values	value	VERB
ijassa-998	427	29	dynamical	dynamical	ADJ
ijassa-998	427	30	analysis	analysis	NOUN
ijassa-998	427	31	optimal	optimal	ADJ
ijassa-998	427	32	control	control	NOUN
ijassa-998	427	33	without	without	ADP
ijassa-998	427	34	state	state	NOUN
ijassa-998	427	35	constraint	constraint	NOUN
ijassa-998	427	36	proof	proof	NOUN
ijassa-998	427	37	of	of	ADP
ijassa-998	427	38	the	the	DET
ijassa-998	427	39	statement	statement	NOUN