id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ajlm-1834	Cook, Annie E.; Jalavu, Thumeka P.; Zemlin, Annalise E.	Audit of amylase and lipase requests in suspected acute pancreatitis and cost implications, South Africa	2022		.htm	text/html	3732	172	45	A recent 2017 review of nine studies by Ismail and Bhayana,8 which included studies carried out by Chang and Chung5 and Hofmeyr et al.,11 concluded a negligible difference in sensitivity and specificity from dual testing of lipase and amylase compared with singular testing of lipase.5,8,11 Whilst studies by Basnayake and Ratnam,9 and Ismail and Bhayana8 have commented that the ratio between amylase and lipase levels could help direct clinicians to the aetiology of AP,8,9 it was generally concluded across several reviews and studies, that dual testing was not a cost-effective option for diagnosis of AP.5,8,11,13 A prospective study by Hofmeyr et al.11 concluded that on admission to Tygerberg Hospital lipase sensitivity was significantly improved at 91% compared with 62% for amylase. Specificities were relatively equivocal for single amylase (98.6%) and lipase tests (96.9%) (Table 2).	cache/ajlm-1834.htm	txt/ajlm-1834.txt