id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ajlm-731	Molaudzi, Mulalo; Molepo, Julitha	The use of real-time polymerase chain reaction and an adenosine deaminase assay for diagnosing pleural tuberculosis	2019		.htm	text/html	4201	233	52	Due to the paucibacillary nature of pleural tuberculosis, the sensitivity of pleural fluid microscopy (about 10%) and culture (about 20%) in pleural tuberculosis cases is low.3,4,5 Culture also has a longer turn-around time, ranging from 4 to 8 weeks.6 The poor sensitivity and specificity of the conventional methods of diagnosis suggest the need for more effective methods, such as an adenosine deaminase assay (ADA) and real-time polymerase chain reaction (qPCR). Pleural fluid ADA has been shown to be a valuable biochemical marker that has a high sensitivity and specificity for pleural tuberculosis diagnosis.7 The use of ADA as a diagnostic marker has additional merits, since results can be produced rapidly.8 Molecular diagnostic tests such as qPCR have been used in the diagnosis of tuberculosis.	cache/ajlm-731.htm	txt/ajlm-731.txt