id	sid	tid	token	lemma	pos
ajlm-1946	1	1	abstract	abstract	ADJ
ajlm-1946	1	2	introduction	introduction	NOUN
ajlm-1946	1	3	signs	sign	NOUN
ajlm-1946	1	4	and	and	CCONJ
ajlm-1946	1	5	symptoms	symptom	NOUN
ajlm-1946	1	6	of	of	ADP
ajlm-1946	1	7	inherited	inherit	VERB
ajlm-1946	1	8	metabolic	metabolic	NOUN
ajlm-1946	1	9	disorders	disorder	NOUN
ajlm-1946	1	10	basic	basic	ADJ
ajlm-1946	1	11	methods	method	NOUN
ajlm-1946	1	12	for	for	ADP
ajlm-1946	1	13	the	the	DET
ajlm-1946	1	14	laboratory	laboratory	NOUN
ajlm-1946	1	15	investigation	investigation	NOUN
ajlm-1946	1	16	of	of	ADP
ajlm-1946	1	17	inborn	inborn	ADJ
ajlm-1946	1	18	errors	error	NOUN
ajlm-1946	1	19	of	of	ADP
ajlm-1946	1	20	metabolism	metabolism	NOUN
ajlm-1946	1	21	purine	purine	NOUN
ajlm-1946	1	22	metabolism	metabolism	NOUN
ajlm-1946	1	23	disorder	disorder	NOUN
ajlm-1946	1	24	conclusion	conclusion	NOUN
ajlm-1946	1	25	acknowledgements	acknowledgement	NOUN
ajlm-1946	1	26	references	reference	NOUN
ajlm-1946	1	27	about	about	ADP
ajlm-1946	1	28	the	the	DET
ajlm-1946	1	29	author(s	author(s	NOUN
ajlm-1946	1	30	)	)	PUNCT
ajlm-1946	1	31	john	john	PROPN
ajlm-1946	1	32	i.	i.	PROPN
ajlm-1946	1	33	anetor	anetor	PROPN
ajlm-1946	1	34	department	department	PROPN
ajlm-1946	1	35	of	of	ADP
ajlm-1946	1	36	chemical	chemical	PROPN
ajlm-1946	1	37	pathology	pathology	PROPN
ajlm-1946	1	38	,	,	PUNCT
ajlm-1946	1	39	faculty	faculty	NOUN
ajlm-1946	1	40	of	of	ADP
ajlm-1946	1	41	basic	basic	ADJ
ajlm-1946	1	42	medical	medical	ADJ
ajlm-1946	1	43	sciences	science	NOUN
ajlm-1946	1	44	,	,	PUNCT
ajlm-1946	1	45	university	university	NOUN
ajlm-1946	1	46	of	of	ADP
ajlm-1946	1	47	ibadan	ibadan	PROPN
ajlm-1946	1	48	,	,	PUNCT
ajlm-1946	1	49	ibadan	ibadan	PROPN
ajlm-1946	1	50	,	,	PUNCT
ajlm-1946	1	51	nigeria	nigeria	PROPN
ajlm-1946	1	52	bose	bose	PROPN
ajlm-1946	1	53	e.	e.	PROPN
ajlm-1946	1	54	orimadegun	orimadegun	PROPN
ajlm-1946	1	55	department	department	PROPN
ajlm-1946	1	56	of	of	ADP
ajlm-1946	1	57	chemical	chemical	PROPN
ajlm-1946	1	58	pathology	pathology	PROPN
ajlm-1946	1	59	,	,	PUNCT
ajlm-1946	1	60	faculty	faculty	NOUN
ajlm-1946	1	61	of	of	ADP
ajlm-1946	1	62	basic	basic	ADJ
ajlm-1946	1	63	medical	medical	ADJ
ajlm-1946	1	64	sciences	science	NOUN
ajlm-1946	1	65	,	,	PUNCT
ajlm-1946	1	66	university	university	NOUN
ajlm-1946	1	67	of	of	ADP
ajlm-1946	1	68	ibadan	ibadan	PROPN
ajlm-1946	1	69	,	,	PUNCT
ajlm-1946	1	70	ibadan	ibadan	PROPN
ajlm-1946	1	71	,	,	PUNCT
ajlm-1946	1	72	nigeria	nigeria	PROPN
ajlm-1946	1	73	gloria	gloria	PROPN
ajlm-1946	1	74	o.	o.	PROPN
ajlm-1946	1	75	anetor	anetor	PROPN
ajlm-1946	1	76	department	department	PROPN
ajlm-1946	1	77	of	of	ADP
ajlm-1946	1	78	public	public	ADJ
ajlm-1946	1	79	health	health	NOUN
ajlm-1946	1	80	science	science	NOUN
ajlm-1946	1	81	,	,	PUNCT
ajlm-1946	1	82	faculty	faculty	NOUN
ajlm-1946	1	83	of	of	ADP
ajlm-1946	1	84	health	health	NOUN
ajlm-1946	1	85	sciences	sciences	PROPN
ajlm-1946	1	86	,	,	PUNCT
ajlm-1946	1	87	national	national	ADJ
ajlm-1946	1	88	open	open	ADJ
ajlm-1946	1	89	university	university	PROPN
ajlm-1946	1	90	of	of	ADP
ajlm-1946	1	91	nigeria	nigeria	PROPN
ajlm-1946	1	92	,	,	PUNCT
ajlm-1946	1	93	abuja	abuja	PROPN
ajlm-1946	1	94	,	,	PUNCT
ajlm-1946	1	95	nigeria	nigeria	PROPN
ajlm-1946	1	96	citation	citation	PROPN
ajlm-1946	1	97	anetor	anetor	PROPN
ajlm-1946	1	98	ji	ji	PROPN
ajlm-1946	1	99	,	,	PUNCT
ajlm-1946	1	100	orimadegun	orimadegun	PROPN
ajlm-1946	1	101	be	be	AUX
ajlm-1946	1	102	,	,	PUNCT
ajlm-1946	1	103	anetor	anetor	NOUN
ajlm-1946	1	104	go	go	VERB
ajlm-1946	1	105	.	.	PUNCT
ajlm-1946	2	1	a	a	DET
ajlm-1946	2	2	pragmatic	pragmatic	ADJ
ajlm-1946	2	3	approach	approach	NOUN
ajlm-1946	2	4	to	to	ADP
ajlm-1946	2	5	the	the	DET
ajlm-1946	2	6	diagnosis	diagnosis	NOUN
ajlm-1946	2	7	of	of	ADP
ajlm-1946	2	8	inborn	inborn	ADJ
ajlm-1946	2	9	errors	error	NOUN
ajlm-1946	2	10	of	of	ADP
ajlm-1946	2	11	metabolism	metabolism	NOUN
ajlm-1946	2	12	in	in	ADP
ajlm-1946	2	13	developing	develop	VERB
ajlm-1946	2	14	countries	country	NOUN
ajlm-1946	2	15	.	.	PUNCT
ajlm-1946	3	1	afr	afr	PROPN
ajlm-1946	3	2	j	j	PROPN
ajlm-1946	3	3	lab	lab	PROPN
ajlm-1946	3	4	med	med	PROPN
ajlm-1946	3	5	.	.	PUNCT
ajlm-1946	4	1	2023;12(1	2023;12(1	NUM
ajlm-1946	4	2	)	)	PUNCT
ajlm-1946	4	3	,	,	PUNCT
ajlm-1946	5	1	a1946	a1946	PROPN
ajlm-1946	5	2	.	.	PUNCT
ajlm-1946	5	3	https://doi.org/10.4102/ajlm.v12i1.1946	https://doi.org/10.4102/ajlm.v12i1.1946	PROPN
ajlm-1946	5	4	review	review	NOUN
ajlm-1946	5	5	article	article	NOUN
ajlm-1946	5	6	a	a	DET
ajlm-1946	5	7	pragmatic	pragmatic	ADJ
ajlm-1946	5	8	approach	approach	NOUN
ajlm-1946	5	9	to	to	ADP
ajlm-1946	5	10	the	the	DET
ajlm-1946	5	11	diagnosis	diagnosis	NOUN
ajlm-1946	5	12	of	of	ADP
ajlm-1946	5	13	inborn	inborn	ADJ
ajlm-1946	5	14	errors	error	NOUN
ajlm-1946	5	15	of	of	ADP
ajlm-1946	5	16	metabolism	metabolism	NOUN
ajlm-1946	5	17	in	in	ADP
ajlm-1946	5	18	developing	develop	VERB
ajlm-1946	5	19	countries	country	NOUN
ajlm-1946	5	20	john	john	PROPN
ajlm-1946	5	21	i.	i.	PROPN
ajlm-1946	5	22	anetor	anetor	PROPN
ajlm-1946	5	23	,	,	PUNCT
ajlm-1946	5	24	bose	bose	PROPN
ajlm-1946	5	25	e.	e.	PROPN
ajlm-1946	5	26	orimadegun	orimadegun	PROPN
ajlm-1946	5	27	,	,	PUNCT
ajlm-1946	5	28	gloria	gloria	PROPN
ajlm-1946	5	29	o.	o.	PROPN
ajlm-1946	5	30	anetor	anetor	PROPN
ajlm-1946	5	31	received	receive	VERB
ajlm-1946	5	32	:	:	PUNCT
ajlm-1946	5	33	30	30	NUM
ajlm-1946	5	34	apr	apr	NOUN
ajlm-1946	5	35	.	.	PUNCT
ajlm-1946	5	36	2022	2022	NUM
ajlm-1946	5	37	;	;	PUNCT
ajlm-1946	5	38	accepted	accept	VERB
ajlm-1946	5	39	:	:	PUNCT
ajlm-1946	5	40	05	05	NUM
ajlm-1946	5	41	apr	apr	NOUN
ajlm-1946	5	42	.	.	PUNCT
ajlm-1946	5	43	2023	2023	NUM
ajlm-1946	5	44	;	;	PUNCT
ajlm-1946	5	45	published	publish	VERB
ajlm-1946	5	46	:	:	PUNCT
ajlm-1946	5	47	30	30	NUM
ajlm-1946	5	48	may	may	PROPN
ajlm-1946	5	49	2023	2023	NUM
ajlm-1946	5	50	copyright	copyright	NOUN
ajlm-1946	5	51	:	:	PUNCT
ajlm-1946	5	52	©	©	PROPN
ajlm-1946	5	53	2023	2023	NUM
ajlm-1946	5	54	.	.	PUNCT
ajlm-1946	6	1	the	the	DET
ajlm-1946	6	2	author(s	author(s	NOUN
ajlm-1946	6	3	)	)	PUNCT
ajlm-1946	6	4	.	.	PUNCT
ajlm-1946	7	1	licensee	licensee	NOUN
ajlm-1946	7	2	:	:	PUNCT
ajlm-1946	7	3	aosis	aosis	NOUN
ajlm-1946	7	4	.	.	PUNCT
ajlm-1946	8	1	this	this	PRON
ajlm-1946	8	2	is	be	AUX
ajlm-1946	8	3	an	an	DET
ajlm-1946	8	4	open	open	ADJ
ajlm-1946	8	5	access	access	NOUN
ajlm-1946	8	6	article	article	NOUN
ajlm-1946	8	7	distributed	distribute	VERB
ajlm-1946	8	8	under	under	ADP
ajlm-1946	8	9	the	the	DET
ajlm-1946	8	10	terms	term	NOUN
ajlm-1946	8	11	of	of	ADP
ajlm-1946	8	12	the	the	DET
ajlm-1946	8	13	creative	creative	ADJ
ajlm-1946	8	14	commons	common	NOUN
ajlm-1946	8	15	attribution	attribution	NOUN
ajlm-1946	8	16	license	license	NOUN
ajlm-1946	8	17	,	,	PUNCT
ajlm-1946	8	18	which	which	PRON
ajlm-1946	8	19	permits	permit	VERB
ajlm-1946	8	20	unrestricted	unrestricted	ADJ
ajlm-1946	8	21	use	use	NOUN
ajlm-1946	8	22	,	,	PUNCT
ajlm-1946	8	23	distribution	distribution	NOUN
ajlm-1946	8	24	,	,	PUNCT
ajlm-1946	8	25	and	and	CCONJ
ajlm-1946	8	26	reproduction	reproduction	NOUN
ajlm-1946	8	27	in	in	ADP
ajlm-1946	8	28	any	any	DET
ajlm-1946	8	29	medium	medium	NOUN
ajlm-1946	8	30	,	,	PUNCT
ajlm-1946	8	31	provided	provide	VERB
ajlm-1946	8	32	the	the	DET
ajlm-1946	8	33	original	original	ADJ
ajlm-1946	8	34	work	work	NOUN
ajlm-1946	8	35	is	be	AUX
ajlm-1946	8	36	properly	properly	ADV
ajlm-1946	8	37	cited	cite	VERB
ajlm-1946	8	38	.	.	PUNCT
ajlm-1946	9	1	abstract	abstract	ADJ
ajlm-1946	9	2	inborn	inborn	ADJ
ajlm-1946	9	3	errors	error	NOUN
ajlm-1946	9	4	of	of	ADP
ajlm-1946	9	5	metabolism	metabolism	NOUN
ajlm-1946	9	6	(	(	PUNCT
ajlm-1946	9	7	iem	iem	PROPN
ajlm-1946	9	8	)	)	PUNCT
ajlm-1946	9	9	are	be	AUX
ajlm-1946	9	10	a	a	DET
ajlm-1946	9	11	group	group	NOUN
ajlm-1946	9	12	of	of	ADP
ajlm-1946	9	13	genetically	genetically	ADV
ajlm-1946	9	14	derived	derive	VERB
ajlm-1946	9	15	diseases	disease	NOUN
ajlm-1946	9	16	that	that	PRON
ajlm-1946	9	17	are	be	AUX
ajlm-1946	9	18	individually	individually	ADV
ajlm-1946	9	19	rare	rare	ADJ
ajlm-1946	9	20	but	but	CCONJ
ajlm-1946	9	21	collectively	collectively	ADV
ajlm-1946	9	22	common	common	ADJ
ajlm-1946	9	23	and	and	CCONJ
ajlm-1946	9	24	can	can	AUX
ajlm-1946	9	25	be	be	AUX
ajlm-1946	9	26	very	very	ADV
ajlm-1946	9	27	severe	severe	ADJ
ajlm-1946	9	28	.	.	PUNCT
ajlm-1946	10	1	while	while	SCONJ
ajlm-1946	10	2	high	high	ADJ
ajlm-1946	10	3	-	-	PUNCT
ajlm-1946	10	4	income	income	NOUN
ajlm-1946	10	5	countries	country	NOUN
ajlm-1946	10	6	usually	usually	ADV
ajlm-1946	10	7	employ	employ	VERB
ajlm-1946	10	8	modern	modern	ADJ
ajlm-1946	10	9	scientific	scientific	ADJ
ajlm-1946	10	10	technologies	technology	NOUN
ajlm-1946	10	11	like	like	ADP
ajlm-1946	10	12	tandem	tandem	PROPN
ajlm-1946	10	13	mass	mass	ADJ
ajlm-1946	10	14	spectrometry	spectrometry	NOUN
ajlm-1946	10	15	for	for	ADP
ajlm-1946	10	16	iem	iem	PROPN
ajlm-1946	10	17	investigation	investigation	NOUN
ajlm-1946	10	18	,	,	PUNCT
ajlm-1946	10	19	these	these	DET
ajlm-1946	10	20	disorders	disorder	NOUN
ajlm-1946	10	21	are	be	AUX
ajlm-1946	10	22	,	,	PUNCT
ajlm-1946	10	23	in	in	ADP
ajlm-1946	10	24	contrast	contrast	NOUN
ajlm-1946	10	25	,	,	PUNCT
ajlm-1946	10	26	only	only	ADV
ajlm-1946	10	27	rarely	rarely	ADV
ajlm-1946	10	28	screened	screen	VERB
ajlm-1946	10	29	for	for	ADP
ajlm-1946	10	30	in	in	ADP
ajlm-1946	10	31	developing	develop	VERB
ajlm-1946	10	32	countries	country	NOUN
ajlm-1946	10	33	due	due	ADP
ajlm-1946	10	34	to	to	ADP
ajlm-1946	10	35	misconceptions	misconception	NOUN
ajlm-1946	10	36	that	that	SCONJ
ajlm-1946	10	37	the	the	DET
ajlm-1946	10	38	required	require	VERB
ajlm-1946	10	39	facilities	facility	NOUN
ajlm-1946	10	40	are	be	AUX
ajlm-1946	10	41	beyond	beyond	ADP
ajlm-1946	10	42	the	the	DET
ajlm-1946	10	43	reach	reach	NOUN
ajlm-1946	10	44	of	of	ADP
ajlm-1946	10	45	these	these	DET
ajlm-1946	10	46	countries	country	NOUN
ajlm-1946	10	47	.	.	PUNCT
ajlm-1946	11	1	this	this	DET
ajlm-1946	11	2	paper	paper	NOUN
ajlm-1946	11	3	attempts	attempt	VERB
ajlm-1946	11	4	to	to	PART
ajlm-1946	11	5	educate	educate	VERB
ajlm-1946	11	6	scientists	scientist	NOUN
ajlm-1946	11	7	and	and	CCONJ
ajlm-1946	11	8	clinicians	clinician	NOUN
ajlm-1946	11	9	in	in	ADP
ajlm-1946	11	10	developing	develop	VERB
ajlm-1946	11	11	countries	country	NOUN
ajlm-1946	11	12	on	on	ADP
ajlm-1946	11	13	low	low	ADJ
ajlm-1946	11	14	-	-	PUNCT
ajlm-1946	11	15	technology	technology	NOUN
ajlm-1946	11	16	iem	iem	ADJ
ajlm-1946	11	17	screening	screen	VERB
ajlm-1946	11	18	methods	method	NOUN
ajlm-1946	11	19	that	that	PRON
ajlm-1946	11	20	only	only	ADV
ajlm-1946	11	21	require	require	VERB
ajlm-1946	11	22	moderate	moderate	ADJ
ajlm-1946	11	23	facilities	facility	NOUN
ajlm-1946	11	24	.	.	PUNCT
ajlm-1946	12	1	although	although	SCONJ
ajlm-1946	12	2	a	a	DET
ajlm-1946	12	3	definitive	definitive	ADJ
ajlm-1946	12	4	diagnosis	diagnosis	NOUN
ajlm-1946	12	5	of	of	ADP
ajlm-1946	12	6	iem	iem	PROPN
ajlm-1946	12	7	may	may	AUX
ajlm-1946	12	8	require	require	VERB
ajlm-1946	12	9	specialised	specialised	ADJ
ajlm-1946	12	10	laboratory	laboratory	NOUN
ajlm-1946	12	11	investigations	investigation	NOUN
ajlm-1946	12	12	and	and	CCONJ
ajlm-1946	12	13	attendant	attendant	ADJ
ajlm-1946	12	14	interpretation	interpretation	NOUN
ajlm-1946	12	15	,	,	PUNCT
ajlm-1946	12	16	in	in	ADP
ajlm-1946	12	17	most	most	ADJ
ajlm-1946	12	18	cases	case	NOUN
ajlm-1946	12	19	,	,	PUNCT
ajlm-1946	12	20	the	the	DET
ajlm-1946	12	21	basic	basic	ADJ
ajlm-1946	12	22	facilities	facility	NOUN
ajlm-1946	12	23	available	available	ADJ
ajlm-1946	12	24	in	in	ADP
ajlm-1946	12	25	the	the	DET
ajlm-1946	12	26	average	average	ADJ
ajlm-1946	12	27	clinical	clinical	ADJ
ajlm-1946	12	28	chemistry	chemistry	NOUN
ajlm-1946	12	29	laboratory	laboratory	NOUN
ajlm-1946	12	30	in	in	ADP
ajlm-1946	12	31	developing	develop	VERB
ajlm-1946	12	32	countries	country	NOUN
ajlm-1946	12	33	can	can	AUX
ajlm-1946	12	34	allow	allow	VERB
ajlm-1946	12	35	the	the	DET
ajlm-1946	12	36	early	early	ADJ
ajlm-1946	12	37	detection	detection	NOUN
ajlm-1946	12	38	of	of	ADP
ajlm-1946	12	39	iem	iem	PROPN
ajlm-1946	12	40	.	.	PUNCT
ajlm-1946	13	1	this	this	DET
ajlm-1946	13	2	early	early	ADJ
ajlm-1946	13	3	detection	detection	NOUN
ajlm-1946	13	4	would	would	AUX
ajlm-1946	13	5	facilitate	facilitate	VERB
ajlm-1946	13	6	critical	critical	ADJ
ajlm-1946	13	7	early	early	ADJ
ajlm-1946	13	8	decision	decision	NOUN
ajlm-1946	13	9	making	making	NOUN
ajlm-1946	13	10	,	,	PUNCT
ajlm-1946	13	11	thus	thus	ADV
ajlm-1946	13	12	leading	lead	VERB
ajlm-1946	13	13	to	to	ADP
ajlm-1946	13	14	better	well	ADJ
ajlm-1946	13	15	management	management	NOUN
ajlm-1946	13	16	,	,	PUNCT
ajlm-1946	13	17	optimised	optimise	VERB
ajlm-1946	13	18	treatment	treatment	NOUN
ajlm-1946	13	19	,	,	PUNCT
ajlm-1946	13	20	and	and	CCONJ
ajlm-1946	13	21	reduced	reduced	ADJ
ajlm-1946	13	22	morbidity	morbidity	NOUN
ajlm-1946	13	23	and	and	CCONJ
ajlm-1946	13	24	or	or	CCONJ
ajlm-1946	13	25	mortality	mortality	NOUN
ajlm-1946	13	26	of	of	ADP
ajlm-1946	13	27	iem	iem	NOUN
ajlm-1946	13	28	in	in	ADP
ajlm-1946	13	29	these	these	DET
ajlm-1946	13	30	resource	resource	NOUN
ajlm-1946	13	31	-	-	PUNCT
ajlm-1946	13	32	limited	limit	VERB
ajlm-1946	13	33	countries	country	NOUN
ajlm-1946	13	34	.	.	PUNCT
ajlm-1946	14	1	with	with	ADP
ajlm-1946	14	2	this	this	DET
ajlm-1946	14	3	approach	approach	NOUN
ajlm-1946	14	4	,	,	PUNCT
ajlm-1946	14	5	a	a	DET
ajlm-1946	14	6	few	few	ADJ
ajlm-1946	14	7	referral	referral	ADJ
ajlm-1946	14	8	centres	centre	NOUN
ajlm-1946	14	9	for	for	ADP
ajlm-1946	14	10	confirmatory	confirmatory	NOUN
ajlm-1946	14	11	investigation	investigation	NOUN
ajlm-1946	14	12	,	,	PUNCT
ajlm-1946	14	13	comparable	comparable	ADJ
ajlm-1946	14	14	to	to	ADP
ajlm-1946	14	15	those	those	PRON
ajlm-1946	14	16	existing	exist	VERB
ajlm-1946	14	17	in	in	ADP
ajlm-1946	14	18	developed	develop	VERB
ajlm-1946	14	19	countries	country	NOUN
ajlm-1946	14	20	,	,	PUNCT
ajlm-1946	14	21	could	could	AUX
ajlm-1946	14	22	be	be	AUX
ajlm-1946	14	23	established	establish	VERB
ajlm-1946	14	24	.	.	PUNCT
ajlm-1946	15	1	this	this	PRON
ajlm-1946	15	2	can	can	AUX
ajlm-1946	15	3	be	be	AUX
ajlm-1946	15	4	integrated	integrate	VERB
ajlm-1946	15	5	into	into	ADP
ajlm-1946	15	6	creative	creative	ADJ
ajlm-1946	15	7	health	health	NOUN
ajlm-1946	15	8	education	education	NOUN
ajlm-1946	15	9	for	for	ADP
ajlm-1946	15	10	healthcare	healthcare	NOUN
ajlm-1946	15	11	professionals	professional	NOUN
ajlm-1946	15	12	and	and	CCONJ
ajlm-1946	15	13	families	family	NOUN
ajlm-1946	15	14	who	who	PRON
ajlm-1946	15	15	have	have	VERB
ajlm-1946	15	16	individuals	individual	NOUN
ajlm-1946	15	17	with	with	ADP
ajlm-1946	15	18	iem	iem	PROPN
ajlm-1946	15	19	.	.	PUNCT
ajlm-1946	16	1	what	what	PRON
ajlm-1946	16	2	this	this	DET
ajlm-1946	16	3	study	study	NOUN
ajlm-1946	16	4	adds	add	VERB
ajlm-1946	16	5	:	:	PUNCT
ajlm-1946	16	6	iems	iem	NOUN
ajlm-1946	16	7	are	be	AUX
ajlm-1946	16	8	important	important	ADJ
ajlm-1946	16	9	enough	enough	ADV
ajlm-1946	16	10	that	that	SCONJ
ajlm-1946	16	11	every	every	DET
ajlm-1946	16	12	country	country	NOUN
ajlm-1946	16	13	,	,	PUNCT
ajlm-1946	16	14	developed	develop	VERB
ajlm-1946	16	15	or	or	CCONJ
ajlm-1946	16	16	developing	develop	VERB
ajlm-1946	16	17	,	,	PUNCT
ajlm-1946	16	18	should	should	AUX
ajlm-1946	16	19	have	have	VERB
ajlm-1946	16	20	screening	screen	VERB
ajlm-1946	16	21	plans	plan	NOUN
ajlm-1946	16	22	and	and	CCONJ
ajlm-1946	16	23	basic	basic	ADJ
ajlm-1946	16	24	laboratory	laboratory	NOUN
ajlm-1946	16	25	facilities	facility	NOUN
ajlm-1946	16	26	that	that	PRON
ajlm-1946	16	27	are	be	AUX
ajlm-1946	16	28	adequate	adequate	ADJ
ajlm-1946	16	29	for	for	ADP
ajlm-1946	16	30	initial	initial	ADJ
ajlm-1946	16	31	iem	iem	ADJ
ajlm-1946	16	32	diagnosis	diagnosis	NOUN
ajlm-1946	16	33	.	.	PUNCT
ajlm-1946	17	1	no	no	DET
ajlm-1946	17	2	country	country	NOUN
ajlm-1946	17	3	should	should	AUX
ajlm-1946	17	4	therefore	therefore	ADV
ajlm-1946	17	5	give	give	VERB
ajlm-1946	17	6	up	up	ADP
ajlm-1946	17	7	on	on	ADP
ajlm-1946	17	8	testing	testing	NOUN
ajlm-1946	17	9	for	for	ADP
ajlm-1946	17	10	iems	iem	NOUN
ajlm-1946	17	11	on	on	ADP
ajlm-1946	17	12	the	the	DET
ajlm-1946	17	13	excuse	excuse	NOUN
ajlm-1946	17	14	of	of	ADP
ajlm-1946	17	15	a	a	DET
ajlm-1946	17	16	paucity	paucity	NOUN
ajlm-1946	17	17	of	of	ADP
ajlm-1946	17	18	advanced	advanced	ADJ
ajlm-1946	17	19	facilities	facility	NOUN
ajlm-1946	17	20	.	.	PUNCT
ajlm-1946	18	1	keywords	keyword	NOUN
ajlm-1946	18	2	:	:	PUNCT
ajlm-1946	18	3	basic	basic	ADJ
ajlm-1946	18	4	laboratory	laboratory	NOUN
ajlm-1946	18	5	investigations	investigation	NOUN
ajlm-1946	18	6	;	;	PUNCT
ajlm-1946	18	7	developing	develop	VERB
ajlm-1946	18	8	countries	country	NOUN
ajlm-1946	18	9	;	;	PUNCT
ajlm-1946	18	10	inborn	inborn	ADJ
ajlm-1946	18	11	errors	error	NOUN
ajlm-1946	18	12	of	of	ADP
ajlm-1946	18	13	metabolism	metabolism	NOUN
ajlm-1946	18	14	;	;	PUNCT
ajlm-1946	18	15	health	health	NOUN
ajlm-1946	18	16	education	education	NOUN
ajlm-1946	18	17	;	;	PUNCT
ajlm-1946	18	18	optimisation	optimisation	NOUN
ajlm-1946	18	19	of	of	ADP
ajlm-1946	18	20	treatment	treatment	NOUN
ajlm-1946	18	21	.	.	PUNCT
ajlm-1946	19	1	introduction	introduction	NOUN
ajlm-1946	19	2	inborn	inborn	ADJ
ajlm-1946	19	3	errors	error	NOUN
ajlm-1946	19	4	of	of	ADP
ajlm-1946	19	5	metabolism	metabolism	NOUN
ajlm-1946	19	6	(	(	PUNCT
ajlm-1946	19	7	iem	iem	PROPN
ajlm-1946	19	8	)	)	PUNCT
ajlm-1946	19	9	,	,	PUNCT
ajlm-1946	19	10	also	also	ADV
ajlm-1946	19	11	referred	refer	VERB
ajlm-1946	19	12	to	to	ADP
ajlm-1946	19	13	as	as	ADP
ajlm-1946	19	14	inherited	inherit	VERB
ajlm-1946	19	15	metabolic	metabolic	NOUN
ajlm-1946	19	16	disorders	disorder	NOUN
ajlm-1946	19	17	,	,	PUNCT
ajlm-1946	19	18	are	be	AUX
ajlm-1946	19	19	mutational	mutational	ADJ
ajlm-1946	19	20	disorders	disorder	NOUN
ajlm-1946	19	21	that	that	PRON
ajlm-1946	19	22	impair	impair	VERB
ajlm-1946	19	23	the	the	DET
ajlm-1946	19	24	function	function	NOUN
ajlm-1946	19	25	of	of	ADP
ajlm-1946	19	26	proteins	protein	NOUN
ajlm-1946	19	27	in	in	ADP
ajlm-1946	19	28	every	every	DET
ajlm-1946	19	29	way	way	NOUN
ajlm-1946	19	30	(	(	PUNCT
ajlm-1946	19	31	mostly	mostly	ADV
ajlm-1946	19	32	enzymatic	enzymatic	ADJ
ajlm-1946	19	33	functions	function	NOUN
ajlm-1946	19	34	)	)	PUNCT
ajlm-1946	19	35	.	.	PUNCT
ajlm-1946	20	1	archibald	archibald	PROPN
ajlm-1946	20	2	garrod	garrod	PROPN
ajlm-1946	20	3	,	,	PUNCT
ajlm-1946	20	4	who	who	PRON
ajlm-1946	20	5	was	be	AUX
ajlm-1946	20	6	the	the	DET
ajlm-1946	20	7	first	first	ADJ
ajlm-1946	20	8	to	to	PART
ajlm-1946	20	9	explain	explain	VERB
ajlm-1946	20	10	the	the	DET
ajlm-1946	20	11	relationship	relationship	NOUN
ajlm-1946	20	12	between	between	ADP
ajlm-1946	20	13	genotype	genotype	NOUN
ajlm-1946	20	14	and	and	CCONJ
ajlm-1946	20	15	phenotype	phenotype	NOUN
ajlm-1946	20	16	,	,	PUNCT
ajlm-1946	20	17	helped	help	VERB
ajlm-1946	20	18	bring	bring	VERB
ajlm-1946	20	19	attention	attention	NOUN
ajlm-1946	20	20	to	to	ADP
ajlm-1946	20	21	iem	iem	NOUN
ajlm-1946	20	22	through	through	ADP
ajlm-1946	20	23	his	his	PRON
ajlm-1946	20	24	pioneering	pioneer	VERB
ajlm-1946	20	25	work	work	NOUN
ajlm-1946	20	26	on	on	ADP
ajlm-1946	20	27	one	one	NUM
ajlm-1946	20	28	of	of	ADP
ajlm-1946	20	29	the	the	DET
ajlm-1946	20	30	first	first	ADJ
ajlm-1946	20	31	types	type	NOUN
ajlm-1946	20	32	of	of	ADP
ajlm-1946	20	33	iem	iem	PROPN
ajlm-1946	20	34	discovered	discover	VERB
ajlm-1946	20	35	–	–	PUNCT
ajlm-1946	20	36	alkaptonuria.1,2	alkaptonuria.1,2	ADV
ajlm-1946	20	37	his	his	PRON
ajlm-1946	20	38	work	work	NOUN
ajlm-1946	20	39	helped	help	VERB
ajlm-1946	20	40	to	to	PART
ajlm-1946	20	41	elucidate	elucidate	VERB
ajlm-1946	20	42	iem	iem	PROPN
ajlm-1946	20	43	,	,	PUNCT
ajlm-1946	20	44	thus	thus	ADV
ajlm-1946	20	45	paving	pave	VERB
ajlm-1946	20	46	the	the	DET
ajlm-1946	20	47	way	way	NOUN
ajlm-1946	20	48	for	for	ADP
ajlm-1946	20	49	the	the	DET
ajlm-1946	20	50	realisation	realisation	NOUN
ajlm-1946	20	51	that	that	SCONJ
ajlm-1946	20	52	every	every	DET
ajlm-1946	20	53	aspect	aspect	NOUN
ajlm-1946	20	54	of	of	ADP
ajlm-1946	20	55	human	human	ADJ
ajlm-1946	20	56	anatomy	anatomy	NOUN
ajlm-1946	20	57	and	and	CCONJ
ajlm-1946	20	58	physiology	physiology	NOUN
ajlm-1946	20	59	is	be	AUX
ajlm-1946	20	60	determined	determine	VERB
ajlm-1946	20	61	by	by	ADP
ajlm-1946	20	62	biochemical	biochemical	ADJ
ajlm-1946	20	63	reactions	reaction	NOUN
ajlm-1946	20	64	catalysed	catalyse	VERB
ajlm-1946	20	65	by	by	ADP
ajlm-1946	20	66	specific	specific	ADJ
ajlm-1946	20	67	enzymes	enzyme	NOUN
ajlm-1946	20	68	,	,	PUNCT
ajlm-1946	20	69	and	and	CCONJ
ajlm-1946	20	70	that	that	SCONJ
ajlm-1946	20	71	enzymes	enzyme	NOUN
ajlm-1946	20	72	are	be	AUX
ajlm-1946	20	73	determined	determine	VERB
ajlm-1946	20	74	by	by	ADP
ajlm-1946	20	75	genetic	genetic	ADJ
ajlm-1946	20	76	constitution	constitution	NOUN
ajlm-1946	20	77	.	.	PUNCT
ajlm-1946	21	1	since	since	SCONJ
ajlm-1946	21	2	then	then	ADV
ajlm-1946	21	3	,	,	PUNCT
ajlm-1946	21	4	several	several	ADJ
ajlm-1946	21	5	additional	additional	ADJ
ajlm-1946	21	6	types	type	NOUN
ajlm-1946	21	7	of	of	ADP
ajlm-1946	21	8	iem	iem	PROPN
ajlm-1946	21	9	have	have	AUX
ajlm-1946	21	10	been	be	AUX
ajlm-1946	21	11	described	describe	VERB
ajlm-1946	21	12	,	,	PUNCT
ajlm-1946	21	13	and	and	CCONJ
ajlm-1946	21	14	many	many	ADJ
ajlm-1946	21	15	more	more	ADJ
ajlm-1946	21	16	are	be	AUX
ajlm-1946	21	17	being	be	AUX
ajlm-1946	21	18	investigated	investigate	VERB
ajlm-1946	21	19	(	(	PUNCT
ajlm-1946	21	20	table	table	NOUN
ajlm-1946	21	21	1).3	1).3	NUM
ajlm-1946	21	22	although	although	SCONJ
ajlm-1946	21	23	iems	iem	NOUN
ajlm-1946	21	24	are	be	AUX
ajlm-1946	21	25	quite	quite	ADV
ajlm-1946	21	26	common	common	ADJ
ajlm-1946	21	27	collectively	collectively	ADV
ajlm-1946	21	28	,	,	PUNCT
ajlm-1946	21	29	individual	individual	ADJ
ajlm-1946	21	30	iem	iem	PROPN
ajlm-1946	21	31	disorders	disorder	NOUN
ajlm-1946	21	32	are	be	AUX
ajlm-1946	21	33	rare	rare	ADJ
ajlm-1946	21	34	.	.	PUNCT
ajlm-1946	22	1	the	the	DET
ajlm-1946	22	2	most	most	ADV
ajlm-1946	22	3	frequently	frequently	ADV
ajlm-1946	22	4	encountered	encounter	VERB
ajlm-1946	22	5	iems	iem	NOUN
ajlm-1946	22	6	are	be	AUX
ajlm-1946	22	7	monogenic	monogenic	ADJ
ajlm-1946	22	8	forms.4,5	forms.4,5	ADV
ajlm-1946	22	9	in	in	ADP
ajlm-1946	22	10	most	most	ADJ
ajlm-1946	22	11	cases	case	NOUN
ajlm-1946	22	12	,	,	PUNCT
ajlm-1946	22	13	iems	iem	NOUN
ajlm-1946	22	14	are	be	AUX
ajlm-1946	22	15	autosomal	autosomal	ADJ
ajlm-1946	22	16	recessive	recessive	ADJ
ajlm-1946	22	17	.	.	PUNCT
ajlm-1946	23	1	table	table	NOUN
ajlm-1946	23	2	1	1	NUM
ajlm-1946	23	3	:	:	PUNCT
ajlm-1946	23	4	 	 	SPACE
ajlm-1946	23	5	types	type	NOUN
ajlm-1946	23	6	of	of	ADP
ajlm-1946	23	7	inborn	inborn	ADJ
ajlm-1946	23	8	errors	error	NOUN
ajlm-1946	23	9	of	of	ADP
ajlm-1946	23	10	metabolism	metabolism	NOUN
ajlm-1946	23	11	commonly	commonly	ADV
ajlm-1946	23	12	investigated	investigate	VERB
ajlm-1946	23	13	using	use	VERB
ajlm-1946	23	14	laboratory	laboratory	NOUN
ajlm-1946	23	15	procedures	procedure	NOUN
ajlm-1946	23	16	.	.	PUNCT
ajlm-1946	24	1	according	accord	VERB
ajlm-1946	24	2	to	to	ADP
ajlm-1946	24	3	the	the	DET
ajlm-1946	24	4	2003	2003	NUM
ajlm-1946	24	5	institute	institute	NOUN
ajlm-1946	24	6	of	of	ADP
ajlm-1946	24	7	medicine	medicine	PROPN
ajlm-1946	24	8	report	report	NOUN
ajlm-1946	24	9	‘	'	PUNCT
ajlm-1946	24	10	reducing	reduce	VERB
ajlm-1946	24	11	birth	birth	NOUN
ajlm-1946	24	12	defects	defect	NOUN
ajlm-1946	24	13	:	:	PUNCT
ajlm-1946	24	14	meeting	meet	VERB
ajlm-1946	24	15	the	the	DET
ajlm-1946	24	16	challenge	challenge	NOUN
ajlm-1946	24	17	in	in	ADP
ajlm-1946	24	18	the	the	DET
ajlm-1946	24	19	developing	develop	VERB
ajlm-1946	24	20	world’,6	world’,6	ADJ
ajlm-1946	24	21	birth	birth	NOUN
ajlm-1946	24	22	defects	defect	NOUN
ajlm-1946	24	23	are	be	AUX
ajlm-1946	24	24	the	the	DET
ajlm-1946	24	25	leading	lead	VERB
ajlm-1946	24	26	cause	cause	NOUN
ajlm-1946	24	27	of	of	ADP
ajlm-1946	24	28	infant	infant	NOUN
ajlm-1946	24	29	mortality	mortality	NOUN
ajlm-1946	24	30	in	in	ADP
ajlm-1946	24	31	many	many	ADJ
ajlm-1946	24	32	regions	region	NOUN
ajlm-1946	24	33	of	of	ADP
ajlm-1946	24	34	developing	develop	VERB
ajlm-1946	24	35	countries.7	countries.7	NOUN
ajlm-1946	24	36	in	in	ADP
ajlm-1946	24	37	these	these	DET
ajlm-1946	24	38	countries	country	NOUN
ajlm-1946	24	39	,	,	PUNCT
ajlm-1946	24	40	malnutrition	malnutrition	NOUN
ajlm-1946	24	41	,	,	PUNCT
ajlm-1946	24	42	poverty	poverty	NOUN
ajlm-1946	24	43	,	,	PUNCT
ajlm-1946	24	44	disease	disease	NOUN
ajlm-1946	24	45	,	,	PUNCT
ajlm-1946	24	46	and	and	CCONJ
ajlm-1946	24	47	lack	lack	NOUN
ajlm-1946	24	48	of	of	ADP
ajlm-1946	24	49	access	access	NOUN
ajlm-1946	24	50	to	to	ADP
ajlm-1946	24	51	healthcare	healthcare	NOUN
ajlm-1946	24	52	elevate	elevate	VERB
ajlm-1946	24	53	the	the	DET
ajlm-1946	24	54	prenatal	prenatal	ADJ
ajlm-1946	24	55	risk	risk	NOUN
ajlm-1946	24	56	of	of	ADP
ajlm-1946	24	57	birth	birth	NOUN
ajlm-1946	24	58	defects	defect	NOUN
ajlm-1946	24	59	and	and	CCONJ
ajlm-1946	24	60	impose	impose	VERB
ajlm-1946	24	61	enormous	enormous	ADJ
ajlm-1946	24	62	personal	personal	ADJ
ajlm-1946	24	63	and	and	CCONJ
ajlm-1946	24	64	societal	societal	ADJ
ajlm-1946	24	65	consequences	consequence	NOUN
ajlm-1946	24	66	.	.	PUNCT
ajlm-1946	25	1	experts	expert	NOUN
ajlm-1946	25	2	in	in	ADP
ajlm-1946	25	3	developed	develop	VERB
ajlm-1946	25	4	countries	country	NOUN
ajlm-1946	25	5	often	often	ADV
ajlm-1946	25	6	have	have	VERB
ajlm-1946	25	7	similar	similar	ADJ
ajlm-1946	25	8	concerns	concern	NOUN
ajlm-1946	25	9	because	because	SCONJ
ajlm-1946	25	10	birth	birth	NOUN
ajlm-1946	25	11	defects	defect	NOUN
ajlm-1946	25	12	are	be	AUX
ajlm-1946	25	13	also	also	ADV
ajlm-1946	25	14	the	the	DET
ajlm-1946	25	15	highest	high	ADJ
ajlm-1946	25	16	single	single	ADJ
ajlm-1946	25	17	cause	cause	NOUN
ajlm-1946	25	18	of	of	ADP
ajlm-1946	25	19	infant	infant	NOUN
ajlm-1946	25	20	death	death	NOUN
ajlm-1946	25	21	in	in	ADP
ajlm-1946	25	22	many	many	ADJ
ajlm-1946	25	23	regions.8	regions.8	PROPN
ajlm-1946	25	24	there	there	PRON
ajlm-1946	25	25	is	be	VERB
ajlm-1946	25	26	a	a	DET
ajlm-1946	25	27	link	link	NOUN
ajlm-1946	25	28	between	between	ADP
ajlm-1946	25	29	birth	birth	NOUN
ajlm-1946	25	30	defects	defect	NOUN
ajlm-1946	25	31	and	and	CCONJ
ajlm-1946	25	32	genetic	genetic	ADJ
ajlm-1946	25	33	abnormalities	abnormality	NOUN
ajlm-1946	25	34	such	such	ADJ
ajlm-1946	25	35	as	as	ADP
ajlm-1946	25	36	iems,7	iems,7	NOUN
ajlm-1946	25	37	and	and	CCONJ
ajlm-1946	25	38	environmental	environmental	ADJ
ajlm-1946	25	39	and	and	CCONJ
ajlm-1946	25	40	genetic	genetic	ADJ
ajlm-1946	25	41	factors	factor	NOUN
ajlm-1946	25	42	are	be	AUX
ajlm-1946	25	43	inextricably	inextricably	ADV
ajlm-1946	25	44	linked	link	VERB
ajlm-1946	25	45	.	.	PUNCT
ajlm-1946	26	1	as	as	SCONJ
ajlm-1946	26	2	these	these	DET
ajlm-1946	26	3	gene	gene	NOUN
ajlm-1946	26	4	-	-	PUNCT
ajlm-1946	26	5	environment	environment	NOUN
ajlm-1946	26	6	interactions	interaction	NOUN
ajlm-1946	26	7	are	be	AUX
ajlm-1946	26	8	important	important	ADJ
ajlm-1946	26	9	in	in	ADP
ajlm-1946	26	10	iem	iem	PROPN
ajlm-1946	26	11	,	,	PUNCT
ajlm-1946	26	12	people	people	NOUN
ajlm-1946	26	13	in	in	ADP
ajlm-1946	26	14	developing	develop	VERB
ajlm-1946	26	15	countries	country	NOUN
ajlm-1946	26	16	are	be	AUX
ajlm-1946	26	17	at	at	ADP
ajlm-1946	26	18	a	a	DET
ajlm-1946	26	19	greater	great	ADJ
ajlm-1946	26	20	risk	risk	NOUN
ajlm-1946	26	21	of	of	ADP
ajlm-1946	26	22	developing	develop	VERB
ajlm-1946	26	23	an	an	DET
ajlm-1946	26	24	iem.9	iem.9	PROPN
ajlm-1946	26	25	this	this	DET
ajlm-1946	26	26	highlights	highlight	NOUN
ajlm-1946	26	27	the	the	DET
ajlm-1946	26	28	need	need	NOUN
ajlm-1946	26	29	for	for	SCONJ
ajlm-1946	26	30	scientists	scientist	NOUN
ajlm-1946	26	31	and	and	CCONJ
ajlm-1946	26	32	doctors	doctor	NOUN
ajlm-1946	26	33	to	to	PART
ajlm-1946	26	34	prioritise	prioritise	VERB
ajlm-1946	26	35	iem	iem	PROPN
ajlm-1946	26	36	detection	detection	NOUN
ajlm-1946	26	37	,	,	PUNCT
ajlm-1946	26	38	management	management	NOUN
ajlm-1946	26	39	,	,	PUNCT
ajlm-1946	26	40	and	and	CCONJ
ajlm-1946	26	41	prevention	prevention	NOUN
ajlm-1946	26	42	through	through	ADP
ajlm-1946	26	43	research	research	NOUN
ajlm-1946	26	44	aimed	aim	VERB
ajlm-1946	26	45	at	at	ADP
ajlm-1946	26	46	identifying	identify	VERB
ajlm-1946	26	47	environmental	environmental	ADJ
ajlm-1946	26	48	red	red	ADJ
ajlm-1946	26	49	flags	flag	NOUN
ajlm-1946	26	50	.	.	PUNCT
ajlm-1946	27	1	a	a	DET
ajlm-1946	27	2	holistic	holistic	ADJ
ajlm-1946	27	3	and	and	CCONJ
ajlm-1946	27	4	integrated	integrated	ADJ
ajlm-1946	27	5	approach	approach	NOUN
ajlm-1946	27	6	is	be	AUX
ajlm-1946	27	7	also	also	ADV
ajlm-1946	27	8	required	require	VERB
ajlm-1946	27	9	for	for	ADP
ajlm-1946	27	10	the	the	DET
ajlm-1946	27	11	effective	effective	ADJ
ajlm-1946	27	12	investigation	investigation	NOUN
ajlm-1946	27	13	and	and	CCONJ
ajlm-1946	27	14	treatment	treatment	NOUN
ajlm-1946	27	15	of	of	ADP
ajlm-1946	27	16	iem	iem	PROPN
ajlm-1946	27	17	.	.	PUNCT
ajlm-1946	28	1	to	to	PART
ajlm-1946	28	2	achieve	achieve	VERB
ajlm-1946	28	3	this	this	PRON
ajlm-1946	28	4	,	,	PUNCT
ajlm-1946	28	5	collaboration	collaboration	NOUN
ajlm-1946	28	6	across	across	ADP
ajlm-1946	28	7	the	the	DET
ajlm-1946	28	8	distinct	distinct	ADJ
ajlm-1946	28	9	disciplines	discipline	NOUN
ajlm-1946	28	10	of	of	ADP
ajlm-1946	28	11	genetics	genetic	NOUN
ajlm-1946	28	12	,	,	PUNCT
ajlm-1946	28	13	evolutionary	evolutionary	ADJ
ajlm-1946	28	14	and	and	CCONJ
ajlm-1946	28	15	developmental	developmental	ADJ
ajlm-1946	28	16	biology	biology	NOUN
ajlm-1946	28	17	,	,	PUNCT
ajlm-1946	28	18	environmental	environmental	ADJ
ajlm-1946	28	19	science	science	NOUN
ajlm-1946	28	20	,	,	PUNCT
ajlm-1946	28	21	and	and	CCONJ
ajlm-1946	28	22	sociology	sociology	NOUN
ajlm-1946	28	23	is	be	AUX
ajlm-1946	28	24	necessary.7	necessary.7	NOUN
ajlm-1946	28	25	this	this	DET
ajlm-1946	28	26	article	article	NOUN
ajlm-1946	28	27	is	be	AUX
ajlm-1946	28	28	,	,	PUNCT
ajlm-1946	28	29	in	in	ADP
ajlm-1946	28	30	part	part	NOUN
ajlm-1946	28	31	,	,	PUNCT
ajlm-1946	28	32	an	an	DET
ajlm-1946	28	33	extended	extended	ADJ
ajlm-1946	28	34	response	response	NOUN
ajlm-1946	28	35	one	one	NUM
ajlm-1946	28	36	of	of	ADP
ajlm-1946	28	37	the	the	DET
ajlm-1946	28	38	authors	author	NOUN
ajlm-1946	28	39	gave	give	VERB
ajlm-1946	28	40	at	at	ADP
ajlm-1946	28	41	a	a	DET
ajlm-1946	28	42	laboratory	laboratory	NOUN
ajlm-1946	28	43	medicine	medicine	NOUN
ajlm-1946	28	44	congress	congress	PROPN
ajlm-1946	28	45	in	in	ADP
ajlm-1946	28	46	north	north	PROPN
ajlm-1946	28	47	africa	africa	PROPN
ajlm-1946	28	48	in	in	ADP
ajlm-1946	28	49	late	late	ADJ
ajlm-1946	28	50	2019	2019	NUM
ajlm-1946	28	51	,	,	PUNCT
ajlm-1946	28	52	where	where	SCONJ
ajlm-1946	28	53	a	a	DET
ajlm-1946	28	54	questioner	questioner	NOUN
ajlm-1946	28	55	inferred	infer	VERB
ajlm-1946	28	56	that	that	SCONJ
ajlm-1946	28	57	iems	iem	NOUN
ajlm-1946	28	58	are	be	AUX
ajlm-1946	28	59	not	not	PART
ajlm-1946	28	60	screened	screen	VERB
ajlm-1946	28	61	for	for	ADP
ajlm-1946	28	62	or	or	CCONJ
ajlm-1946	28	63	diagnosed	diagnose	VERB
ajlm-1946	28	64	in	in	ADP
ajlm-1946	28	65	developing	develop	VERB
ajlm-1946	28	66	nations	nation	NOUN
ajlm-1946	28	67	because	because	SCONJ
ajlm-1946	28	68	the	the	DET
ajlm-1946	28	69	needed	need	VERB
ajlm-1946	28	70	specialist	specialist	NOUN
ajlm-1946	28	71	laboratory	laboratory	NOUN
ajlm-1946	28	72	facilities	facility	NOUN
ajlm-1946	28	73	are	be	AUX
ajlm-1946	28	74	not	not	PART
ajlm-1946	28	75	available	available	ADJ
ajlm-1946	28	76	.	.	PUNCT
ajlm-1946	29	1	although	although	SCONJ
ajlm-1946	29	2	a	a	DET
ajlm-1946	29	3	recent	recent	ADJ
ajlm-1946	29	4	report	report	NOUN
ajlm-1946	29	5	from	from	ADP
ajlm-1946	29	6	colombia	colombia	PROPN
ajlm-1946	29	7	(	(	PUNCT
ajlm-1946	29	8	a	a	DET
ajlm-1946	29	9	developing	develop	VERB
ajlm-1946	29	10	country	country	NOUN
ajlm-1946	29	11	)	)	PUNCT
ajlm-1946	29	12	by	by	ADP
ajlm-1946	29	13	echeverri	echeverri	NOUN
ajlm-1946	29	14	et	et	PROPN
ajlm-1946	29	15	al.10	al.10	PROPN
ajlm-1946	29	16	outlines	outline	VERB
ajlm-1946	29	17	the	the	DET
ajlm-1946	29	18	activities	activity	NOUN
ajlm-1946	29	19	in	in	ADP
ajlm-1946	29	20	their	their	PRON
ajlm-1946	29	21	reference	reference	NOUN
ajlm-1946	29	22	centre	centre	NOUN
ajlm-1946	29	23	that	that	PRON
ajlm-1946	29	24	support	support	VERB
ajlm-1946	29	25	the	the	DET
ajlm-1946	29	26	questioner	questioner	NOUN
ajlm-1946	29	27	’s	’s	PART
ajlm-1946	29	28	position	position	NOUN
ajlm-1946	29	29	,	,	PUNCT
ajlm-1946	29	30	their	their	PRON
ajlm-1946	29	31	diagnostic	diagnostic	ADJ
ajlm-1946	29	32	approach	approach	NOUN
ajlm-1946	29	33	is	be	AUX
ajlm-1946	29	34	not	not	PART
ajlm-1946	29	35	pragmatic	pragmatic	ADJ
ajlm-1946	29	36	or	or	CCONJ
ajlm-1946	29	37	applicable	applicable	ADJ
ajlm-1946	29	38	to	to	ADP
ajlm-1946	29	39	most	most	ADJ
ajlm-1946	29	40	developing	develop	VERB
ajlm-1946	29	41	countries	country	NOUN
ajlm-1946	29	42	but	but	CCONJ
ajlm-1946	29	43	may	may	AUX
ajlm-1946	29	44	apply	apply	VERB
ajlm-1946	29	45	to	to	ADP
ajlm-1946	29	46	referral	referral	ADJ
ajlm-1946	29	47	centres	centre	NOUN
ajlm-1946	29	48	in	in	ADP
ajlm-1946	29	49	developing	develop	VERB
ajlm-1946	29	50	countries	country	NOUN
ajlm-1946	29	51	.	.	PUNCT
ajlm-1946	30	1	nevertheless	nevertheless	ADV
ajlm-1946	30	2	,	,	PUNCT
ajlm-1946	30	3	they	they	PRON
ajlm-1946	30	4	did	do	AUX
ajlm-1946	30	5	make	make	VERB
ajlm-1946	30	6	a	a	DET
ajlm-1946	30	7	notable	notable	ADJ
ajlm-1946	30	8	point	point	NOUN
ajlm-1946	30	9	about	about	ADP
ajlm-1946	30	10	the	the	DET
ajlm-1946	30	11	importance	importance	NOUN
ajlm-1946	30	12	of	of	ADP
ajlm-1946	30	13	health	health	NOUN
ajlm-1946	30	14	education	education	NOUN
ajlm-1946	30	15	for	for	ADP
ajlm-1946	30	16	both	both	DET
ajlm-1946	30	17	health	health	NOUN
ajlm-1946	30	18	and	and	CCONJ
ajlm-1946	30	19	non	non	ADJ
ajlm-1946	30	20	-	-	ADJ
ajlm-1946	30	21	health	health	ADJ
ajlm-1946	30	22	professionals	professional	NOUN
ajlm-1946	30	23	,	,	PUNCT
ajlm-1946	30	24	who	who	PRON
ajlm-1946	30	25	are	be	AUX
ajlm-1946	30	26	critical	critical	ADJ
ajlm-1946	30	27	and	and	CCONJ
ajlm-1946	30	28	underappreciated	underappreciated	ADJ
ajlm-1946	30	29	in	in	ADP
ajlm-1946	30	30	the	the	DET
ajlm-1946	30	31	field	field	NOUN
ajlm-1946	30	32	of	of	ADP
ajlm-1946	30	33	iem	iem	PROPN
ajlm-1946	30	34	.	.	PUNCT
ajlm-1946	31	1	a	a	DET
ajlm-1946	31	2	recent	recent	ADJ
ajlm-1946	31	3	report	report	NOUN
ajlm-1946	31	4	by	by	ADP
ajlm-1946	31	5	civallero	civallero	NOUN
ajlm-1946	31	6	,	,	PUNCT
ajlm-1946	31	7	de	de	PROPN
ajlm-1946	31	8	kremer	kremer	PROPN
ajlm-1946	31	9	and	and	CCONJ
ajlm-1946	31	10	giugliani11	giugliani11	NOUN
ajlm-1946	31	11	proposed	propose	VERB
ajlm-1946	31	12	the	the	DET
ajlm-1946	31	13	use	use	NOUN
ajlm-1946	31	14	of	of	ADP
ajlm-1946	31	15	a	a	DET
ajlm-1946	31	16	few	few	ADJ
ajlm-1946	31	17	simple	simple	ADJ
ajlm-1946	31	18	and	and	CCONJ
ajlm-1946	31	19	affordable	affordable	ADJ
ajlm-1946	31	20	instruments	instrument	NOUN
ajlm-1946	31	21	such	such	ADJ
ajlm-1946	31	22	as	as	ADP
ajlm-1946	31	23	spectrophotometer	spectrophotometer	NOUN
ajlm-1946	31	24	and	and	CCONJ
ajlm-1946	31	25	gas	gas	NOUN
ajlm-1946	31	26	chromatography	chromatography	NOUN
ajlm-1946	31	27	-	-	PUNCT
ajlm-1946	31	28	mass	mass	NOUN
ajlm-1946	31	29	spectrometry	spectrometry	NOUN
ajlm-1946	31	30	for	for	ADP
ajlm-1946	31	31	iem	iem	PROPN
ajlm-1946	31	32	investigations	investigation	NOUN
ajlm-1946	31	33	,	,	PUNCT
ajlm-1946	31	34	as	as	SCONJ
ajlm-1946	31	35	these	these	PRON
ajlm-1946	31	36	can	can	AUX
ajlm-1946	31	37	give	give	VERB
ajlm-1946	31	38	an	an	DET
ajlm-1946	31	39	enormous	enormous	ADJ
ajlm-1946	31	40	amount	amount	NOUN
ajlm-1946	31	41	of	of	ADP
ajlm-1946	31	42	information	information	NOUN
ajlm-1946	31	43	that	that	PRON
ajlm-1946	31	44	can	can	AUX
ajlm-1946	31	45	be	be	AUX
ajlm-1946	31	46	adapted	adapt	VERB
ajlm-1946	31	47	to	to	ADP
ajlm-1946	31	48	the	the	DET
ajlm-1946	31	49	needs	need	NOUN
ajlm-1946	31	50	of	of	ADP
ajlm-1946	31	51	health	health	NOUN
ajlm-1946	31	52	facilities	facility	NOUN
ajlm-1946	31	53	in	in	ADP
ajlm-1946	31	54	developing	develop	VERB
ajlm-1946	31	55	countries	country	NOUN
ajlm-1946	31	56	.	.	PUNCT
ajlm-1946	32	1	this	this	DET
ajlm-1946	32	2	approach	approach	NOUN
ajlm-1946	32	3	contrasts	contrast	VERB
ajlm-1946	32	4	that	that	SCONJ
ajlm-1946	32	5	of	of	ADP
ajlm-1946	32	6	echeverri	echeverri	NOUN
ajlm-1946	32	7	et	et	NOUN
ajlm-1946	32	8	al.10	al.10	NOUN
ajlm-1946	32	9	and	and	CCONJ
ajlm-1946	32	10	may	may	AUX
ajlm-1946	32	11	be	be	AUX
ajlm-1946	32	12	more	more	ADV
ajlm-1946	32	13	relevant	relevant	ADJ
ajlm-1946	32	14	to	to	ADP
ajlm-1946	32	15	health	health	NOUN
ajlm-1946	32	16	facilities	facility	NOUN
ajlm-1946	32	17	in	in	ADP
ajlm-1946	32	18	developing	develop	VERB
ajlm-1946	32	19	countries	country	NOUN
ajlm-1946	32	20	.	.	PUNCT
ajlm-1946	33	1	the	the	DET
ajlm-1946	33	2	mayo	mayo	PROPN
ajlm-1946	33	3	clinic	clinic	PROPN
ajlm-1946	33	4	has	have	AUX
ajlm-1946	33	5	also	also	ADV
ajlm-1946	33	6	outlined	outline	VERB
ajlm-1946	33	7	another	another	DET
ajlm-1946	33	8	diagnostic	diagnostic	ADJ
ajlm-1946	33	9	approach	approach	NOUN
ajlm-1946	33	10	that	that	PRON
ajlm-1946	33	11	can	can	AUX
ajlm-1946	33	12	be	be	AUX
ajlm-1946	33	13	modified	modify	VERB
ajlm-1946	33	14	for	for	ADP
ajlm-1946	33	15	the	the	DET
ajlm-1946	33	16	qualitative	qualitative	ADJ
ajlm-1946	33	17	and	and	CCONJ
ajlm-1946	33	18	quantitative	quantitative	ADJ
ajlm-1946	33	19	determination	determination	NOUN
ajlm-1946	33	20	of	of	ADP
ajlm-1946	33	21	diagnostic	diagnostic	ADJ
ajlm-1946	33	22	markers	marker	NOUN
ajlm-1946	33	23	of	of	ADP
ajlm-1946	33	24	iem	iem	PROPN
ajlm-1946	33	25	(	(	PUNCT
ajlm-1946	33	26	table	table	NOUN
ajlm-1946	33	27	2).12	2).12	NUM
ajlm-1946	33	28	table	table	NOUN
ajlm-1946	33	29	2	2	NUM
ajlm-1946	33	30	:	:	PUNCT
ajlm-1946	33	31	 	 	SPACE
ajlm-1946	33	32	general	general	ADJ
ajlm-1946	33	33	methods	method	NOUN
ajlm-1946	33	34	for	for	ADP
ajlm-1946	33	35	the	the	DET
ajlm-1946	33	36	qualitative	qualitative	ADJ
ajlm-1946	33	37	and	and	CCONJ
ajlm-1946	33	38	quantitative	quantitative	ADJ
ajlm-1946	33	39	determination	determination	NOUN
ajlm-1946	33	40	of	of	ADP
ajlm-1946	33	41	diagnostic	diagnostic	ADJ
ajlm-1946	33	42	markers	marker	NOUN
ajlm-1946	33	43	of	of	ADP
ajlm-1946	33	44	inborn	inborn	ADJ
ajlm-1946	33	45	errors	error	NOUN
ajlm-1946	33	46	of	of	ADP
ajlm-1946	33	47	metabolism	metabolism	NOUN
ajlm-1946	33	48	.	.	PUNCT
ajlm-1946	34	1	clinically	clinically	ADV
ajlm-1946	34	2	,	,	PUNCT
ajlm-1946	34	3	iem	iem	PROPN
ajlm-1946	34	4	can	can	AUX
ajlm-1946	34	5	be	be	AUX
ajlm-1946	34	6	grouped	group	VERB
ajlm-1946	34	7	into	into	ADP
ajlm-1946	34	8	three	three	NUM
ajlm-1946	34	9	categories	category	NOUN
ajlm-1946	34	10	,	,	PUNCT
ajlm-1946	34	11	namely	namely	ADV
ajlm-1946	34	12	,	,	PUNCT
ajlm-1946	34	13	disorders	disorder	NOUN
ajlm-1946	34	14	that	that	PRON
ajlm-1946	34	15	cause	cause	VERB
ajlm-1946	34	16	intoxication	intoxication	NOUN
ajlm-1946	34	17	,	,	PUNCT
ajlm-1946	34	18	disorders	disorder	NOUN
ajlm-1946	34	19	that	that	PRON
ajlm-1946	34	20	affect	affect	VERB
ajlm-1946	34	21	energy	energy	NOUN
ajlm-1946	34	22	metabolism	metabolism	NOUN
ajlm-1946	34	23	,	,	PUNCT
ajlm-1946	34	24	and	and	CCONJ
ajlm-1946	34	25	disorders	disorder	NOUN
ajlm-1946	34	26	that	that	PRON
ajlm-1946	34	27	affect	affect	VERB
ajlm-1946	34	28	complex	complex	ADJ
ajlm-1946	34	29	molecules.13,14	molecules.13,14	NOUN
ajlm-1946	34	30	in	in	ADP
ajlm-1946	34	31	disorders	disorder	NOUN
ajlm-1946	34	32	of	of	ADP
ajlm-1946	34	33	intoxication	intoxication	NOUN
ajlm-1946	34	34	,	,	PUNCT
ajlm-1946	34	35	metabolites	metabolite	NOUN
ajlm-1946	34	36	accumulate	accumulate	VERB
ajlm-1946	34	37	at	at	ADP
ajlm-1946	34	38	toxic	toxic	ADJ
ajlm-1946	34	39	concentrations	concentration	NOUN
ajlm-1946	34	40	and	and	CCONJ
ajlm-1946	34	41	the	the	DET
ajlm-1946	34	42	accumulating	accumulate	VERB
ajlm-1946	34	43	metabolites	metabolite	NOUN
ajlm-1946	34	44	are	be	AUX
ajlm-1946	34	45	usually	usually	ADV
ajlm-1946	34	46	proximal	proximal	ADJ
ajlm-1946	34	47	to	to	ADP
ajlm-1946	34	48	the	the	DET
ajlm-1946	34	49	metabolic	metabolic	NOUN
ajlm-1946	34	50	block	block	NOUN
ajlm-1946	34	51	.	.	PUNCT
ajlm-1946	35	1	consequently	consequently	ADV
ajlm-1946	35	2	,	,	PUNCT
ajlm-1946	35	3	identifying	identify	VERB
ajlm-1946	35	4	these	these	DET
ajlm-1946	35	5	metabolites	metabolite	NOUN
ajlm-1946	35	6	provides	provide	VERB
ajlm-1946	35	7	a	a	DET
ajlm-1946	35	8	basis	basis	NOUN
ajlm-1946	35	9	for	for	ADP
ajlm-1946	35	10	diagnosis	diagnosis	NOUN
ajlm-1946	35	11	using	use	VERB
ajlm-1946	35	12	basic	basic	ADJ
ajlm-1946	35	13	laboratory	laboratory	NOUN
ajlm-1946	35	14	facilities	facility	NOUN
ajlm-1946	35	15	,	,	PUNCT
ajlm-1946	35	16	which	which	PRON
ajlm-1946	35	17	are	be	AUX
ajlm-1946	35	18	readily	readily	ADV
ajlm-1946	35	19	affordable	affordable	ADJ
ajlm-1946	35	20	in	in	ADP
ajlm-1946	35	21	resource	resource	NOUN
ajlm-1946	35	22	-	-	PUNCT
ajlm-1946	35	23	limited	limit	VERB
ajlm-1946	35	24	settings	setting	NOUN
ajlm-1946	35	25	.	.	PUNCT
ajlm-1946	36	1	therefore	therefore	ADV
ajlm-1946	36	2	,	,	PUNCT
ajlm-1946	36	3	this	this	DET
ajlm-1946	36	4	article	article	NOUN
ajlm-1946	36	5	aims	aim	VERB
ajlm-1946	36	6	to	to	PART
ajlm-1946	36	7	raise	raise	VERB
ajlm-1946	36	8	awareness	awareness	NOUN
ajlm-1946	36	9	of	of	ADP
ajlm-1946	36	10	basic	basic	ADJ
ajlm-1946	36	11	investigations	investigation	NOUN
ajlm-1946	36	12	that	that	PRON
ajlm-1946	36	13	can	can	AUX
ajlm-1946	36	14	detect	detect	VERB
ajlm-1946	36	15	iem	iem	PROPN
ajlm-1946	36	16	early	early	ADV
ajlm-1946	36	17	and	and	CCONJ
ajlm-1946	36	18	do	do	AUX
ajlm-1946	36	19	not	not	PART
ajlm-1946	36	20	require	require	VERB
ajlm-1946	36	21	expensive	expensive	ADJ
ajlm-1946	36	22	or	or	CCONJ
ajlm-1946	36	23	sophisticated	sophisticated	ADJ
ajlm-1946	36	24	equipment	equipment	NOUN
ajlm-1946	36	25	commonly	commonly	ADV
ajlm-1946	36	26	used	use	VERB
ajlm-1946	36	27	in	in	ADP
ajlm-1946	36	28	developed	develop	VERB
ajlm-1946	36	29	countries	country	NOUN
ajlm-1946	36	30	.	.	PUNCT
ajlm-1946	37	1	a	a	DET
ajlm-1946	37	2	quasi	quasi	ADJ
ajlm-1946	37	3	-	-	ADJ
ajlm-1946	37	4	systematic	systematic	ADJ
ajlm-1946	37	5	review	review	NOUN
ajlm-1946	37	6	was	be	AUX
ajlm-1946	37	7	conducted	conduct	VERB
ajlm-1946	37	8	where	where	SCONJ
ajlm-1946	37	9	the	the	DET
ajlm-1946	37	10	science	science	NOUN
ajlm-1946	37	11	citation	citation	NOUN
ajlm-1946	37	12	index	index	NOUN
ajlm-1946	37	13	and	and	CCONJ
ajlm-1946	37	14	pubmed	pubmed	PROPN
ajlm-1946	37	15	databases	database	NOUN
ajlm-1946	37	16	were	be	AUX
ajlm-1946	37	17	searched	search	VERB
ajlm-1946	37	18	,	,	PUNCT
ajlm-1946	37	19	independent	independent	ADJ
ajlm-1946	37	20	of	of	ADP
ajlm-1946	37	21	date	date	NOUN
ajlm-1946	37	22	of	of	ADP
ajlm-1946	37	23	publication	publication	NOUN
ajlm-1946	37	24	,	,	PUNCT
ajlm-1946	37	25	for	for	ADP
ajlm-1946	37	26	articles	article	NOUN
ajlm-1946	37	27	on	on	ADP
ajlm-1946	37	28	iem	iem	PROPN
ajlm-1946	37	29	.	.	PUNCT
ajlm-1946	38	1	we	we	PRON
ajlm-1946	38	2	prioritised	prioritise	VERB
ajlm-1946	38	3	articles	article	NOUN
ajlm-1946	38	4	that	that	PRON
ajlm-1946	38	5	were	be	AUX
ajlm-1946	38	6	published	publish	VERB
ajlm-1946	38	7	in	in	ADP
ajlm-1946	38	8	developing	develop	VERB
ajlm-1946	38	9	countries	country	NOUN
ajlm-1946	38	10	and	and	CCONJ
ajlm-1946	38	11	articles	article	NOUN
ajlm-1946	38	12	published	publish	VERB
ajlm-1946	38	13	by	by	ADP
ajlm-1946	38	14	leading	lead	VERB
ajlm-1946	38	15	authorities	authority	NOUN
ajlm-1946	38	16	and	and	CCONJ
ajlm-1946	38	17	institutions	institution	NOUN
ajlm-1946	38	18	.	.	PUNCT
ajlm-1946	39	1	we	we	PRON
ajlm-1946	39	2	also	also	ADV
ajlm-1946	39	3	included	include	VERB
ajlm-1946	39	4	the	the	DET
ajlm-1946	39	5	early	early	ADJ
ajlm-1946	39	6	lectures	lecture	NOUN
ajlm-1946	39	7	of	of	ADP
ajlm-1946	39	8	the	the	DET
ajlm-1946	39	9	‘	'	PUNCT
ajlm-1946	39	10	father	father	NOUN
ajlm-1946	39	11	of	of	ADP
ajlm-1946	39	12	inborn	inborn	ADJ
ajlm-1946	39	13	errors	error	NOUN
ajlm-1946	39	14	of	of	ADP
ajlm-1946	39	15	metabolism	metabolism	NOUN
ajlm-1946	39	16	’	'	PUNCT
ajlm-1946	39	17	,	,	PUNCT
ajlm-1946	39	18	archibald	archibald	PROPN
ajlm-1946	39	19	garrod.1,2	garrod.1,2	PROPN
ajlm-1946	39	20	we	we	PRON
ajlm-1946	39	21	conducted	conduct	VERB
ajlm-1946	39	22	a	a	DET
ajlm-1946	39	23	limited	limited	ADJ
ajlm-1946	39	24	synthesis	synthesis	NOUN
ajlm-1946	39	25	of	of	ADP
ajlm-1946	39	26	all	all	DET
ajlm-1946	39	27	retrieved	retrieve	VERB
ajlm-1946	39	28	articles	article	NOUN
ajlm-1946	39	29	and	and	CCONJ
ajlm-1946	39	30	found	find	VERB
ajlm-1946	39	31	evidence	evidence	NOUN
ajlm-1946	39	32	of	of	ADP
ajlm-1946	39	33	the	the	DET
ajlm-1946	39	34	paucity	paucity	NOUN
ajlm-1946	39	35	of	of	ADP
ajlm-1946	39	36	investigations	investigation	NOUN
ajlm-1946	39	37	of	of	ADP
ajlm-1946	39	38	iem	iem	NOUN
ajlm-1946	39	39	in	in	ADP
ajlm-1946	39	40	developing	develop	VERB
ajlm-1946	39	41	countries	country	NOUN
ajlm-1946	39	42	due	due	ADP
ajlm-1946	39	43	to	to	ADP
ajlm-1946	39	44	the	the	DET
ajlm-1946	39	45	lack	lack	NOUN
ajlm-1946	39	46	of	of	ADP
ajlm-1946	39	47	facilities	facility	NOUN
ajlm-1946	39	48	,	,	PUNCT
ajlm-1946	39	49	which	which	PRON
ajlm-1946	39	50	we	we	PRON
ajlm-1946	39	51	have	have	AUX
ajlm-1946	39	52	tried	try	VERB
ajlm-1946	39	53	to	to	PART
ajlm-1946	39	54	address	address	VERB
ajlm-1946	39	55	in	in	ADP
ajlm-1946	39	56	this	this	DET
ajlm-1946	39	57	article	article	NOUN
ajlm-1946	39	58	.	.	PUNCT
ajlm-1946	40	1	a	a	DET
ajlm-1946	40	2	major	major	ADJ
ajlm-1946	40	3	limitation	limitation	NOUN
ajlm-1946	40	4	of	of	ADP
ajlm-1946	40	5	our	our	PRON
ajlm-1946	40	6	approach	approach	NOUN
ajlm-1946	40	7	is	be	AUX
ajlm-1946	40	8	that	that	SCONJ
ajlm-1946	40	9	it	it	PRON
ajlm-1946	40	10	only	only	ADV
ajlm-1946	40	11	provides	provide	VERB
ajlm-1946	40	12	a	a	DET
ajlm-1946	40	13	cursory	cursory	ADJ
ajlm-1946	40	14	overview	overview	NOUN
ajlm-1946	40	15	of	of	ADP
ajlm-1946	40	16	the	the	DET
ajlm-1946	40	17	topic	topic	NOUN
ajlm-1946	40	18	.	.	PUNCT
ajlm-1946	41	1	signs	sign	NOUN
ajlm-1946	41	2	and	and	CCONJ
ajlm-1946	41	3	symptoms	symptom	NOUN
ajlm-1946	41	4	of	of	ADP
ajlm-1946	41	5	inherited	inherit	VERB
ajlm-1946	41	6	metabolic	metabolic	NOUN
ajlm-1946	41	7	disorders	disorder	NOUN
ajlm-1946	41	8	there	there	PRON
ajlm-1946	41	9	are	be	VERB
ajlm-1946	41	10	some	some	DET
ajlm-1946	41	11	common	common	ADJ
ajlm-1946	41	12	signs	sign	NOUN
ajlm-1946	41	13	and	and	CCONJ
ajlm-1946	41	14	symptoms	symptom	NOUN
ajlm-1946	41	15	that	that	PRON
ajlm-1946	41	16	raise	raise	VERB
ajlm-1946	41	17	the	the	DET
ajlm-1946	41	18	index	index	NOUN
ajlm-1946	41	19	of	of	ADP
ajlm-1946	41	20	suspicion	suspicion	NOUN
ajlm-1946	41	21	of	of	ADP
ajlm-1946	41	22	iem.15	iem.15	NOUN
ajlm-1946	41	23	these	these	PRON
ajlm-1946	41	24	include	include	VERB
ajlm-1946	41	25	acute	acute	ADJ
ajlm-1946	41	26	life	life	NOUN
ajlm-1946	41	27	-	-	PUNCT
ajlm-1946	41	28	threatening	threaten	VERB
ajlm-1946	41	29	crisis	crisis	NOUN
ajlm-1946	41	30	,	,	PUNCT
ajlm-1946	41	31	lethargy	lethargy	NOUN
ajlm-1946	41	32	or	or	CCONJ
ajlm-1946	41	33	coma	coma	NOUN
ajlm-1946	41	34	with	with	ADP
ajlm-1946	41	35	or	or	CCONJ
ajlm-1946	41	36	without	without	ADP
ajlm-1946	41	37	a	a	DET
ajlm-1946	41	38	symptom	symptom	NOUN
ajlm-1946	41	39	-	-	PUNCT
ajlm-1946	41	40	free	free	ADJ
ajlm-1946	41	41	period	period	NOUN
ajlm-1946	41	42	,	,	PUNCT
ajlm-1946	41	43	seizures	seizure	NOUN
ajlm-1946	41	44	,	,	PUNCT
ajlm-1946	41	45	persistent	persistent	ADJ
ajlm-1946	41	46	vomiting	vomiting	NOUN
ajlm-1946	41	47	,	,	PUNCT
ajlm-1946	41	48	respiratory	respiratory	ADJ
ajlm-1946	41	49	distress	distress	NOUN
ajlm-1946	41	50	syndrome	syndrome	NOUN
ajlm-1946	41	51	(	(	PUNCT
ajlm-1946	41	52	apnoea	apnoea	NOUN
ajlm-1946	41	53	)	)	PUNCT
ajlm-1946	41	54	,	,	PUNCT
ajlm-1946	41	55	poor	poor	ADJ
ajlm-1946	41	56	feeding	feeding	NOUN
ajlm-1946	41	57	/	/	SYM
ajlm-1946	41	58	failure	failure	NOUN
ajlm-1946	41	59	to	to	PART
ajlm-1946	41	60	thrive	thrive	VERB
ajlm-1946	41	61	,	,	PUNCT
ajlm-1946	41	62	hypotonicity	hypotonicity	ADJ
ajlm-1946	41	63	/	/	SYM
ajlm-1946	41	64	hypertonicity	hypertonicity	NOUN
ajlm-1946	41	65	(	(	PUNCT
ajlm-1946	41	66	ataxia	ataxia	NOUN
ajlm-1946	41	67	,	,	PUNCT
ajlm-1946	41	68	posturing	posturing	NOUN
ajlm-1946	41	69	)	)	PUNCT
ajlm-1946	41	70	,	,	PUNCT
ajlm-1946	41	71	hepatosplenomegaly	hepatosplenomegaly	PROPN
ajlm-1946	41	72	/	/	SYM
ajlm-1946	41	73	jaundice	jaundice	NOUN
ajlm-1946	41	74	,	,	PUNCT
ajlm-1946	41	75	dysmorphic	dysmorphic	ADJ
ajlm-1946	41	76	features	feature	NOUN
ajlm-1946	41	77	(	(	PUNCT
ajlm-1946	41	78	facial	facial	ADJ
ajlm-1946	41	79	coarsening	coarsening	NOUN
ajlm-1946	41	80	)	)	PUNCT
ajlm-1946	41	81	,	,	PUNCT
ajlm-1946	41	82	macroglossia	macroglossia	NOUN
ajlm-1946	41	83	,	,	PUNCT
ajlm-1946	41	84	ocular	ocular	ADJ
ajlm-1946	41	85	features	feature	NOUN
ajlm-1946	41	86	(	(	PUNCT
ajlm-1946	41	87	cataract	cataract	NOUN
ajlm-1946	41	88	,	,	PUNCT
ajlm-1946	41	89	corneal	corneal	ADJ
ajlm-1946	41	90	clouding	clouding	NOUN
ajlm-1946	41	91	,	,	PUNCT
ajlm-1946	41	92	abnormal	abnormal	ADJ
ajlm-1946	41	93	eye	eye	NOUN
ajlm-1946	41	94	movements	movement	NOUN
ajlm-1946	41	95	)	)	PUNCT
ajlm-1946	41	96	,	,	PUNCT
ajlm-1946	41	97	coarse	coarse	ADJ
ajlm-1946	41	98	hair	hair	NOUN
ajlm-1946	41	99	with	with	ADP
ajlm-1946	41	100	abnormal	abnormal	ADJ
ajlm-1946	41	101	texture	texture	NOUN
ajlm-1946	41	102	,	,	PUNCT
ajlm-1946	41	103	abnormal	abnormal	ADJ
ajlm-1946	41	104	odour	odour	NOUN
ajlm-1946	41	105	of	of	ADP
ajlm-1946	41	106	urine	urine	NOUN
ajlm-1946	41	107	/	/	SYM
ajlm-1946	41	108	body	body	NOUN
ajlm-1946	41	109	,	,	PUNCT
ajlm-1946	41	110	loss	loss	NOUN
ajlm-1946	41	111	of	of	ADP
ajlm-1946	41	112	developmental	developmental	ADJ
ajlm-1946	41	113	milestones	milestone	NOUN
ajlm-1946	41	114	,	,	PUNCT
ajlm-1946	41	115	unusual	unusual	ADJ
ajlm-1946	41	116	responses	response	NOUN
ajlm-1946	41	117	to	to	ADP
ajlm-1946	41	118	fasting	fast	VERB
ajlm-1946	41	119	and	and	CCONJ
ajlm-1946	41	120	intercurrent	intercurrent	ADJ
ajlm-1946	41	121	infection	infection	NOUN
ajlm-1946	41	122	(	(	PUNCT
ajlm-1946	41	123	von	von	PROPN
ajlm-1946	41	124	gierke	gierke	PROPN
ajlm-1946	41	125	’s	’s	PART
ajlm-1946	41	126	disease	disease	NOUN
ajlm-1946	41	127	,	,	PUNCT
ajlm-1946	41	128	type	type	NOUN
ajlm-1946	41	129	1	1	NUM
ajlm-1946	41	130	glycogenosis	glycogenosis	NOUN
ajlm-1946	41	131	)	)	PUNCT
ajlm-1946	41	132	,	,	PUNCT
ajlm-1946	41	133	and	and	CCONJ
ajlm-1946	41	134	fluctuating	fluctuate	VERB
ajlm-1946	41	135	neurological	neurological	ADJ
ajlm-1946	41	136	status	status	NOUN
ajlm-1946	41	137	.	.	PUNCT
ajlm-1946	42	1	basic	basic	ADJ
ajlm-1946	42	2	methods	method	NOUN
ajlm-1946	42	3	for	for	ADP
ajlm-1946	42	4	the	the	DET
ajlm-1946	42	5	laboratory	laboratory	NOUN
ajlm-1946	42	6	investigation	investigation	NOUN
ajlm-1946	42	7	of	of	ADP
ajlm-1946	42	8	inborn	inborn	ADJ
ajlm-1946	42	9	errors	error	NOUN
ajlm-1946	42	10	of	of	ADP
ajlm-1946	42	11	metabolism	metabolism	NOUN
ajlm-1946	42	12	alkaptonuria	alkaptonuria	NOUN
ajlm-1946	42	13	alkaptonuria	alkaptonuria	PROPN
ajlm-1946	42	14	is	be	AUX
ajlm-1946	42	15	one	one	NUM
ajlm-1946	42	16	of	of	ADP
ajlm-1946	42	17	the	the	DET
ajlm-1946	42	18	earliest	early	ADJ
ajlm-1946	42	19	iems	iem	NOUN
ajlm-1946	42	20	described	describe	VERB
ajlm-1946	42	21	by	by	ADP
ajlm-1946	42	22	garrod.2	garrod.2	NOUN
ajlm-1946	42	23	this	this	PRON
ajlm-1946	42	24	is	be	AUX
ajlm-1946	42	25	a	a	DET
ajlm-1946	42	26	benign	benign	ADJ
ajlm-1946	42	27	disorder	disorder	NOUN
ajlm-1946	42	28	that	that	PRON
ajlm-1946	42	29	poses	pose	VERB
ajlm-1946	42	30	no	no	DET
ajlm-1946	42	31	danger	danger	NOUN
ajlm-1946	42	32	to	to	ADP
ajlm-1946	42	33	life	life	NOUN
ajlm-1946	42	34	except	except	SCONJ
ajlm-1946	42	35	for	for	ADP
ajlm-1946	42	36	ochronosis	ochronosis	NOUN
ajlm-1946	42	37	(	(	PUNCT
ajlm-1946	42	38	darkening	darkening	NOUN
ajlm-1946	42	39	)	)	PUNCT
ajlm-1946	42	40	of	of	ADP
ajlm-1946	42	41	the	the	DET
ajlm-1946	42	42	cartilage	cartilage	NOUN
ajlm-1946	42	43	,	,	PUNCT
ajlm-1946	42	44	and	and	CCONJ
ajlm-1946	42	45	patients	patient	NOUN
ajlm-1946	42	46	with	with	ADP
ajlm-1946	42	47	this	this	DET
ajlm-1946	42	48	condition	condition	NOUN
ajlm-1946	42	49	are	be	AUX
ajlm-1946	42	50	prone	prone	ADJ
ajlm-1946	42	51	to	to	ADP
ajlm-1946	42	52	arthritis	arthritis	NOUN
ajlm-1946	42	53	from	from	ADP
ajlm-1946	42	54	the	the	DET
ajlm-1946	42	55	fourth	fourth	ADJ
ajlm-1946	42	56	decade	decade	NOUN
ajlm-1946	42	57	of	of	ADP
ajlm-1946	42	58	life	life	NOUN
ajlm-1946	42	59	.	.	PUNCT
ajlm-1946	43	1	alkaptonuria	alkaptonuria	PROPN
ajlm-1946	43	2	is	be	AUX
ajlm-1946	43	3	characterised	characterise	VERB
ajlm-1946	43	4	by	by	ADP
ajlm-1946	43	5	the	the	DET
ajlm-1946	43	6	darkening	darkening	NOUN
ajlm-1946	43	7	of	of	ADP
ajlm-1946	43	8	standing	stand	VERB
ajlm-1946	43	9	urine	urine	NOUN
ajlm-1946	43	10	,	,	PUNCT
ajlm-1946	43	11	and	and	CCONJ
ajlm-1946	43	12	a	a	DET
ajlm-1946	43	13	simple	simple	ADJ
ajlm-1946	43	14	benedict	benedict	NOUN
ajlm-1946	43	15	’s	’s	PART
ajlm-1946	43	16	reaction	reaction	NOUN
ajlm-1946	43	17	on	on	ADP
ajlm-1946	43	18	the	the	DET
ajlm-1946	43	19	urine	urine	NOUN
ajlm-1946	43	20	sample	sample	NOUN
ajlm-1946	43	21	will	will	AUX
ajlm-1946	43	22	give	give	VERB
ajlm-1946	43	23	a	a	DET
ajlm-1946	43	24	positive	positive	ADJ
ajlm-1946	43	25	reaction	reaction	NOUN
ajlm-1946	43	26	.	.	PUNCT
ajlm-1946	44	1	all	all	PRON
ajlm-1946	44	2	that	that	PRON
ajlm-1946	44	3	is	be	AUX
ajlm-1946	44	4	required	require	VERB
ajlm-1946	44	5	for	for	ADP
ajlm-1946	44	6	this	this	DET
ajlm-1946	44	7	test	test	NOUN
ajlm-1946	44	8	is	be	AUX
ajlm-1946	44	9	copper	copper	NOUN
ajlm-1946	44	10	sulphate	sulphate	NOUN
ajlm-1946	44	11	in	in	ADP
ajlm-1946	44	12	an	an	DET
ajlm-1946	44	13	alkaline	alkaline	NOUN
ajlm-1946	44	14	medium	medium	NOUN
ajlm-1946	44	15	,	,	PUNCT
ajlm-1946	44	16	which	which	PRON
ajlm-1946	44	17	is	be	AUX
ajlm-1946	44	18	inexpensive	inexpensive	ADJ
ajlm-1946	44	19	.	.	PUNCT
ajlm-1946	45	1	phenylketonuria	phenylketonuria	NOUN
ajlm-1946	45	2	some	some	DET
ajlm-1946	45	3	basic	basic	ADJ
ajlm-1946	45	4	investigations	investigation	NOUN
ajlm-1946	45	5	can	can	AUX
ajlm-1946	45	6	also	also	ADV
ajlm-1946	45	7	aid	aid	VERB
ajlm-1946	45	8	in	in	ADP
ajlm-1946	45	9	the	the	DET
ajlm-1946	45	10	early	early	ADJ
ajlm-1946	45	11	detection	detection	NOUN
ajlm-1946	45	12	of	of	ADP
ajlm-1946	45	13	phenylketonuria	phenylketonuria	NOUN
ajlm-1946	45	14	,	,	PUNCT
ajlm-1946	45	15	which	which	PRON
ajlm-1946	45	16	is	be	AUX
ajlm-1946	45	17	one	one	NUM
ajlm-1946	45	18	of	of	ADP
ajlm-1946	45	19	the	the	DET
ajlm-1946	45	20	most	most	ADV
ajlm-1946	45	21	well	well	ADV
ajlm-1946	45	22	-	-	PUNCT
ajlm-1946	45	23	known	know	VERB
ajlm-1946	45	24	and	and	CCONJ
ajlm-1946	45	25	potentially	potentially	ADV
ajlm-1946	45	26	fatal	fatal	ADJ
ajlm-1946	45	27	iems	iem	NOUN
ajlm-1946	45	28	that	that	PRON
ajlm-1946	45	29	is	be	AUX
ajlm-1946	45	30	associated	associate	VERB
ajlm-1946	45	31	with	with	ADP
ajlm-1946	45	32	profound	profound	ADJ
ajlm-1946	45	33	intelligence	intelligence	NOUN
ajlm-1946	45	34	quotient	quotient	NOUN
ajlm-1946	45	35	loss	loss	NOUN
ajlm-1946	45	36	and	and	CCONJ
ajlm-1946	45	37	severe	severe	ADJ
ajlm-1946	45	38	mental	mental	ADJ
ajlm-1946	45	39	retardation	retardation	NOUN
ajlm-1946	45	40	(	(	PUNCT
ajlm-1946	45	41	mr	mr	PROPN
ajlm-1946	45	42	)	)	PUNCT
ajlm-1946	45	43	.	.	PUNCT
ajlm-1946	46	1	phenylketonuria	phenylketonuria	NOUN
ajlm-1946	46	2	can	can	AUX
ajlm-1946	46	3	easily	easily	ADV
ajlm-1946	46	4	be	be	AUX
ajlm-1946	46	5	diagnosed	diagnose	VERB
ajlm-1946	46	6	using	use	VERB
ajlm-1946	46	7	the	the	DET
ajlm-1946	46	8	fecl3	fecl3	PROPN
ajlm-1946	46	9	test	test	NOUN
ajlm-1946	46	10	(	(	PUNCT
ajlm-1946	46	11	on	on	ADP
ajlm-1946	46	12	which	which	PRON
ajlm-1946	46	13	the	the	DET
ajlm-1946	46	14	phenistix	phenistix	NOUN
ajlm-1946	46	15	test	test	NOUN
ajlm-1946	46	16	is	be	AUX
ajlm-1946	46	17	based	base	VERB
ajlm-1946	46	18	)	)	PUNCT
ajlm-1946	46	19	that	that	PRON
ajlm-1946	46	20	requires	require	VERB
ajlm-1946	46	21	only	only	ADV
ajlm-1946	46	22	a	a	DET
ajlm-1946	46	23	10	10	NUM
ajlm-1946	46	24	%	%	NOUN
ajlm-1946	46	25	fecl3	fecl3	NOUN
ajlm-1946	46	26	solution	solution	NOUN
ajlm-1946	46	27	,	,	PUNCT
ajlm-1946	46	28	the	the	DET
ajlm-1946	46	29	guthrie	guthrie	PROPN
ajlm-1946	46	30	test	test	NOUN
ajlm-1946	46	31	,	,	PUNCT
ajlm-1946	46	32	amino	amino	NOUN
ajlm-1946	46	33	acid	acid	NOUN
ajlm-1946	46	34	analysis	analysis	NOUN
ajlm-1946	46	35	using	use	VERB
ajlm-1946	46	36	high	high	ADJ
ajlm-1946	46	37	-	-	PUNCT
ajlm-1946	46	38	performance	performance	NOUN
ajlm-1946	46	39	liquid	liquid	ADJ
ajlm-1946	46	40	chromatography	chromatography	NOUN
ajlm-1946	46	41	or	or	CCONJ
ajlm-1946	46	42	tandem	tandem	NOUN
ajlm-1946	46	43	mass	mass	ADJ
ajlm-1946	46	44	spectrometry	spectrometry	NOUN
ajlm-1946	46	45	.	.	PUNCT
ajlm-1946	47	1	the	the	DET
ajlm-1946	47	2	latter	latter	ADJ
ajlm-1946	47	3	two	two	NUM
ajlm-1946	47	4	methods	method	NOUN
ajlm-1946	47	5	may	may	AUX
ajlm-1946	47	6	be	be	AUX
ajlm-1946	47	7	expensive	expensive	ADJ
ajlm-1946	47	8	but	but	CCONJ
ajlm-1946	47	9	could	could	AUX
ajlm-1946	47	10	be	be	AUX
ajlm-1946	47	11	made	make	VERB
ajlm-1946	47	12	available	available	ADJ
ajlm-1946	47	13	in	in	ADP
ajlm-1946	47	14	a	a	DET
ajlm-1946	47	15	referral	referral	ADJ
ajlm-1946	47	16	centre	centre	NOUN
ajlm-1946	47	17	.	.	PUNCT
ajlm-1946	48	1	the	the	DET
ajlm-1946	48	2	guthrie	guthrie	PROPN
ajlm-1946	48	3	screening	screening	NOUN
ajlm-1946	48	4	test	test	NOUN
ajlm-1946	48	5	for	for	ADP
ajlm-1946	48	6	increased	increase	VERB
ajlm-1946	48	7	phenylalanine	phenylalanine	NOUN
ajlm-1946	48	8	in	in	ADP
ajlm-1946	48	9	serum	serum	NOUN
ajlm-1946	48	10	is	be	AUX
ajlm-1946	48	11	one	one	NUM
ajlm-1946	48	12	alternative	alternative	NOUN
ajlm-1946	48	13	to	to	ADP
ajlm-1946	48	14	specialised	specialised	ADJ
ajlm-1946	48	15	high	high	ADJ
ajlm-1946	48	16	-	-	PUNCT
ajlm-1946	48	17	performance	performance	NOUN
ajlm-1946	48	18	liquid	liquid	ADJ
ajlm-1946	48	19	chromatography	chromatography	NOUN
ajlm-1946	48	20	for	for	ADP
ajlm-1946	48	21	amino	amino	NOUN
ajlm-1946	48	22	acid	acid	NOUN
ajlm-1946	48	23	analysis	analysis	NOUN
ajlm-1946	48	24	that	that	PRON
ajlm-1946	48	25	is	be	AUX
ajlm-1946	48	26	within	within	ADP
ajlm-1946	48	27	the	the	DET
ajlm-1946	48	28	reach	reach	NOUN
ajlm-1946	48	29	of	of	ADP
ajlm-1946	48	30	many	many	ADJ
ajlm-1946	48	31	laboratories	laboratory	NOUN
ajlm-1946	48	32	in	in	ADP
ajlm-1946	48	33	developing	develop	VERB
ajlm-1946	48	34	countries	country	NOUN
ajlm-1946	48	35	.	.	PUNCT
ajlm-1946	49	1	it	it	PRON
ajlm-1946	49	2	is	be	AUX
ajlm-1946	49	3	a	a	DET
ajlm-1946	49	4	microbiological	microbiological	ADJ
ajlm-1946	49	5	test	test	NOUN
ajlm-1946	49	6	that	that	PRON
ajlm-1946	49	7	relies	rely	VERB
ajlm-1946	49	8	on	on	ADP
ajlm-1946	49	9	phenylalanine	phenylalanine	NOUN
ajlm-1946	49	10	’s	’s	PART
ajlm-1946	49	11	ability	ability	NOUN
ajlm-1946	49	12	to	to	PART
ajlm-1946	49	13	counteract	counteract	VERB
ajlm-1946	49	14	the	the	DET
ajlm-1946	49	15	effects	effect	NOUN
ajlm-1946	49	16	of	of	ADP
ajlm-1946	49	17	a	a	DET
ajlm-1946	49	18	metabolic	metabolic	NOUN
ajlm-1946	49	19	antagonist	antagonist	NOUN
ajlm-1946	49	20	on	on	ADP
ajlm-1946	49	21	the	the	DET
ajlm-1946	49	22	growth	growth	NOUN
ajlm-1946	49	23	of	of	ADP
ajlm-1946	49	24	a	a	DET
ajlm-1946	49	25	bacillus	bacillus	NOUN
ajlm-1946	49	26	subtilis	subtili	NOUN
ajlm-1946	49	27	strain	strain	NOUN
ajlm-1946	49	28	that	that	PRON
ajlm-1946	49	29	requires	require	VERB
ajlm-1946	49	30	phenylalanine	phenylalanine	NOUN
ajlm-1946	49	31	as	as	ADP
ajlm-1946	49	32	a	a	DET
ajlm-1946	49	33	growth	growth	NOUN
ajlm-1946	49	34	factor	factor	NOUN
ajlm-1946	49	35	.	.	PUNCT
ajlm-1946	50	1	the	the	DET
ajlm-1946	50	2	test	test	NOUN
ajlm-1946	50	3	procedure	procedure	NOUN
ajlm-1946	50	4	involves	involve	VERB
ajlm-1946	50	5	the	the	DET
ajlm-1946	50	6	suspension	suspension	NOUN
ajlm-1946	50	7	of	of	ADP
ajlm-1946	50	8	b.	b.	PROPN
ajlm-1946	50	9	subtilis	subtilis	PROPN
ajlm-1946	50	10	spores	spore	NOUN
ajlm-1946	50	11	in	in	ADP
ajlm-1946	50	12	an	an	DET
ajlm-1946	50	13	agar	agar	NOUN
ajlm-1946	50	14	medium	medium	NOUN
ajlm-1946	50	15	containing	contain	VERB
ajlm-1946	50	16	a	a	DET
ajlm-1946	50	17	minimum	minimum	NOUN
ajlm-1946	50	18	amount	amount	NOUN
ajlm-1946	50	19	of	of	ADP
ajlm-1946	50	20	growth	growth	NOUN
ajlm-1946	50	21	nutrients	nutrient	NOUN
ajlm-1946	50	22	plus	plus	CCONJ
ajlm-1946	50	23	a	a	DET
ajlm-1946	50	24	fixed	fix	VERB
ajlm-1946	50	25	amount	amount	NOUN
ajlm-1946	50	26	of	of	ADP
ajlm-1946	50	27	the	the	DET
ajlm-1946	50	28	metabolic	metabolic	NOUN
ajlm-1946	50	29	antagonist	antagonist	NOUN
ajlm-1946	50	30	,	,	PUNCT
ajlm-1946	50	31	β-2	β-2	ADJ
ajlm-1946	50	32	-	-	PUNCT
ajlm-1946	50	33	thienylalanine	thienylalanine	NOUN
ajlm-1946	50	34	,	,	PUNCT
ajlm-1946	50	35	which	which	PRON
ajlm-1946	50	36	is	be	AUX
ajlm-1946	50	37	a	a	DET
ajlm-1946	50	38	non	non	ADJ
ajlm-1946	50	39	-	-	ADJ
ajlm-1946	50	40	protein	protein	ADJ
ajlm-1946	50	41	amino	amino	NOUN
ajlm-1946	50	42	acid	acid	NOUN
ajlm-1946	50	43	similar	similar	ADJ
ajlm-1946	50	44	in	in	ADP
ajlm-1946	50	45	structure	structure	NOUN
ajlm-1946	50	46	to	to	ADP
ajlm-1946	50	47	phenylalanine	phenylalanine	NOUN
ajlm-1946	50	48	.	.	PUNCT
ajlm-1946	51	1	when	when	SCONJ
ajlm-1946	51	2	the	the	DET
ajlm-1946	51	3	infant	infant	NOUN
ajlm-1946	51	4	is	be	AUX
ajlm-1946	51	5	6	6	NUM
ajlm-1946	51	6	days	day	NOUN
ajlm-1946	51	7	old	old	ADJ
ajlm-1946	51	8	(	(	PUNCT
ajlm-1946	51	9	or	or	CCONJ
ajlm-1946	51	10	as	as	ADV
ajlm-1946	51	11	soon	soon	ADV
ajlm-1946	51	12	as	as	ADP
ajlm-1946	51	13	possible	possible	ADJ
ajlm-1946	51	14	if	if	SCONJ
ajlm-1946	51	15	the	the	DET
ajlm-1946	51	16	baby	baby	NOUN
ajlm-1946	51	17	is	be	AUX
ajlm-1946	51	18	being	be	AUX
ajlm-1946	51	19	treated	treat	VERB
ajlm-1946	51	20	with	with	ADP
ajlm-1946	51	21	antibiotics	antibiotic	NOUN
ajlm-1946	51	22	that	that	PRON
ajlm-1946	51	23	interfere	interfere	VERB
ajlm-1946	51	24	with	with	ADP
ajlm-1946	51	25	the	the	DET
ajlm-1946	51	26	test	test	NOUN
ajlm-1946	51	27	)	)	PUNCT
ajlm-1946	51	28	,	,	PUNCT
ajlm-1946	51	29	blood	blood	NOUN
ajlm-1946	51	30	is	be	AUX
ajlm-1946	51	31	drawn	draw	VERB
ajlm-1946	51	32	by	by	ADP
ajlm-1946	51	33	heel	heel	NOUN
ajlm-1946	51	34	prick	prick	NOUN
ajlm-1946	51	35	onto	onto	ADP
ajlm-1946	51	36	filter	filter	NOUN
ajlm-1946	51	37	paper	paper	NOUN
ajlm-1946	51	38	,	,	PUNCT
ajlm-1946	51	39	dried	dry	VERB
ajlm-1946	51	40	,	,	PUNCT
ajlm-1946	51	41	and	and	CCONJ
ajlm-1946	51	42	sent	send	VERB
ajlm-1946	51	43	to	to	ADP
ajlm-1946	51	44	the	the	DET
ajlm-1946	51	45	laboratory	laboratory	NOUN
ajlm-1946	51	46	.	.	PUNCT
ajlm-1946	52	1	these	these	DET
ajlm-1946	52	2	blood	blood	NOUN
ajlm-1946	52	3	spots	spot	NOUN
ajlm-1946	52	4	are	be	AUX
ajlm-1946	52	5	cut	cut	VERB
ajlm-1946	52	6	into	into	ADP
ajlm-1946	52	7	uniform	uniform	ADJ
ajlm-1946	52	8	discs	disc	NOUN
ajlm-1946	52	9	and	and	CCONJ
ajlm-1946	52	10	then	then	ADV
ajlm-1946	52	11	placed	place	VERB
ajlm-1946	52	12	on	on	ADP
ajlm-1946	52	13	agar	agar	NOUN
ajlm-1946	52	14	plates	plate	NOUN
ajlm-1946	52	15	inoculated	inoculate	VERB
ajlm-1946	52	16	with	with	ADP
ajlm-1946	52	17	the	the	DET
ajlm-1946	52	18	b.	b.	PROPN
ajlm-1946	52	19	subtilis	subtilis	PROPN
ajlm-1946	52	20	isolate	isolate	PROPN
ajlm-1946	52	21	,	,	PUNCT
ajlm-1946	52	22	with	with	ADP
ajlm-1946	52	23	the	the	DET
ajlm-1946	52	24	only	only	ADJ
ajlm-1946	52	25	source	source	NOUN
ajlm-1946	52	26	of	of	ADP
ajlm-1946	52	27	phenylalanine	phenylalanine	NOUN
ajlm-1946	52	28	being	be	AUX
ajlm-1946	52	29	the	the	DET
ajlm-1946	52	30	blood	blood	NOUN
ajlm-1946	52	31	spot	spot	NOUN
ajlm-1946	52	32	.	.	PUNCT
ajlm-1946	53	1	the	the	DET
ajlm-1946	53	2	blood	blood	NOUN
ajlm-1946	53	3	spot	spot	NOUN
ajlm-1946	53	4	discs	disc	NOUN
ajlm-1946	53	5	are	be	AUX
ajlm-1946	53	6	compared	compare	VERB
ajlm-1946	53	7	to	to	ADP
ajlm-1946	53	8	discs	disc	NOUN
ajlm-1946	53	9	containing	contain	VERB
ajlm-1946	53	10	known	know	VERB
ajlm-1946	53	11	amounts	amount	NOUN
ajlm-1946	53	12	of	of	ADP
ajlm-1946	53	13	phenylalanine	phenylalanine	NOUN
ajlm-1946	53	14	.	.	PUNCT
ajlm-1946	54	1	if	if	SCONJ
ajlm-1946	54	2	the	the	DET
ajlm-1946	54	3	serum	serum	NOUN
ajlm-1946	54	4	contains	contain	VERB
ajlm-1946	54	5	a	a	DET
ajlm-1946	54	6	high	high	ADJ
ajlm-1946	54	7	level	level	NOUN
ajlm-1946	54	8	of	of	ADP
ajlm-1946	54	9	phenylalanine	phenylalanine	NOUN
ajlm-1946	54	10	,	,	PUNCT
ajlm-1946	54	11	the	the	DET
ajlm-1946	54	12	phenylalanine	phenylalanine	NOUN
ajlm-1946	54	13	will	will	AUX
ajlm-1946	54	14	diffuse	diffuse	VERB
ajlm-1946	54	15	from	from	ADP
ajlm-1946	54	16	the	the	DET
ajlm-1946	54	17	sample	sample	NOUN
ajlm-1946	54	18	disc	disc	NOUN
ajlm-1946	54	19	into	into	ADP
ajlm-1946	54	20	the	the	DET
ajlm-1946	54	21	bacterial	bacterial	ADJ
ajlm-1946	54	22	medium	medium	NOUN
ajlm-1946	54	23	to	to	PART
ajlm-1946	54	24	counteract	counteract	VERB
ajlm-1946	54	25	the	the	DET
ajlm-1946	54	26	inhibitory	inhibitory	ADJ
ajlm-1946	54	27	effect	effect	NOUN
ajlm-1946	54	28	of	of	ADP
ajlm-1946	54	29	thienylalanine	thienylalanine	NOUN
ajlm-1946	54	30	,	,	PUNCT
ajlm-1946	54	31	resulting	result	VERB
ajlm-1946	54	32	in	in	ADP
ajlm-1946	54	33	a	a	DET
ajlm-1946	54	34	ring	ring	NOUN
ajlm-1946	54	35	of	of	ADP
ajlm-1946	54	36	bacterial	bacterial	ADJ
ajlm-1946	54	37	growth	growth	NOUN
ajlm-1946	54	38	around	around	ADP
ajlm-1946	54	39	the	the	DET
ajlm-1946	54	40	disc	disc	NOUN
ajlm-1946	54	41	.	.	PUNCT
ajlm-1946	55	1	if	if	SCONJ
ajlm-1946	55	2	the	the	DET
ajlm-1946	55	3	phenylalanine	phenylalanine	NOUN
ajlm-1946	55	4	level	level	NOUN
ajlm-1946	55	5	is	be	AUX
ajlm-1946	55	6	less	less	ADJ
ajlm-1946	55	7	than	than	ADP
ajlm-1946	55	8	2	2	NUM
ajlm-1946	55	9	mg	mg	PROPN
ajlm-1946	55	10	/	/	SYM
ajlm-1946	55	11	dl	dl	PROPN
ajlm-1946	55	12	,	,	PUNCT
ajlm-1946	55	13	the	the	DET
ajlm-1946	55	14	growth	growth	NOUN
ajlm-1946	55	15	inhibition	inhibition	NOUN
ajlm-1946	55	16	will	will	AUX
ajlm-1946	55	17	not	not	PART
ajlm-1946	55	18	be	be	AUX
ajlm-1946	55	19	overcome	overcome	VERB
ajlm-1946	55	20	,	,	PUNCT
ajlm-1946	55	21	and	and	CCONJ
ajlm-1946	55	22	no	no	DET
ajlm-1946	55	23	bacterial	bacterial	ADJ
ajlm-1946	55	24	growth	growth	NOUN
ajlm-1946	55	25	will	will	AUX
ajlm-1946	55	26	be	be	AUX
ajlm-1946	55	27	observed	observe	VERB
ajlm-1946	55	28	.	.	PUNCT
ajlm-1946	56	1	as	as	SCONJ
ajlm-1946	56	2	false	false	ADJ
ajlm-1946	56	3	positives	positive	NOUN
ajlm-1946	56	4	can	can	AUX
ajlm-1946	56	5	occur	occur	VERB
ajlm-1946	56	6	,	,	PUNCT
ajlm-1946	56	7	positive	positive	ADJ
ajlm-1946	56	8	results	result	NOUN
ajlm-1946	56	9	should	should	AUX
ajlm-1946	56	10	be	be	AUX
ajlm-1946	56	11	confirmed	confirm	VERB
ajlm-1946	56	12	using	use	VERB
ajlm-1946	56	13	a	a	DET
ajlm-1946	56	14	chemical	chemical	NOUN
ajlm-1946	56	15	method	method	NOUN
ajlm-1946	56	16	or	or	CCONJ
ajlm-1946	56	17	chromatography	chromatography	NOUN
ajlm-1946	56	18	.	.	PUNCT
ajlm-1946	57	1	to	to	PART
ajlm-1946	57	2	avoid	avoid	VERB
ajlm-1946	57	3	false	false	ADJ
ajlm-1946	57	4	positive	positive	ADJ
ajlm-1946	57	5	results	result	NOUN
ajlm-1946	57	6	due	due	ADP
ajlm-1946	57	7	to	to	ADP
ajlm-1946	57	8	liver	liver	NOUN
ajlm-1946	57	9	immaturity	immaturity	NOUN
ajlm-1946	57	10	,	,	PUNCT
ajlm-1946	57	11	tests	test	NOUN
ajlm-1946	57	12	should	should	AUX
ajlm-1946	57	13	not	not	PART
ajlm-1946	57	14	be	be	AUX
ajlm-1946	57	15	performed	perform	VERB
ajlm-1946	57	16	on	on	ADP
ajlm-1946	57	17	premature	premature	ADJ
ajlm-1946	57	18	infants	infant	NOUN
ajlm-1946	57	19	or	or	CCONJ
ajlm-1946	57	20	full	full	ADJ
ajlm-1946	57	21	-	-	PUNCT
ajlm-1946	57	22	term	term	NOUN
ajlm-1946	57	23	babies	baby	NOUN
ajlm-1946	57	24	immediately	immediately	ADV
ajlm-1946	57	25	after	after	ADP
ajlm-1946	57	26	birth	birth	NOUN
ajlm-1946	57	27	.	.	PUNCT
ajlm-1946	58	1	the	the	DET
ajlm-1946	58	2	infant	infant	NOUN
ajlm-1946	58	3	should	should	AUX
ajlm-1946	58	4	also	also	ADV
ajlm-1946	58	5	be	be	AUX
ajlm-1946	58	6	on	on	ADP
ajlm-1946	58	7	a	a	DET
ajlm-1946	58	8	phenylalanine	phenylalanine	NOUN
ajlm-1946	58	9	-	-	PUNCT
ajlm-1946	58	10	containing	contain	VERB
ajlm-1946	58	11	diet	diet	NOUN
ajlm-1946	58	12	for	for	ADP
ajlm-1946	58	13	at	at	ADV
ajlm-1946	58	14	least	least	ADV
ajlm-1946	58	15	24	24	NUM
ajlm-1946	58	16	h	h	NOUN
ajlm-1946	58	17	before	before	SCONJ
ajlm-1946	58	18	the	the	DET
ajlm-1946	58	19	sample	sample	NOUN
ajlm-1946	58	20	is	be	AUX
ajlm-1946	58	21	collected.3	collected.3	PROPN
ajlm-1946	58	22	maple	maple	NOUN
ajlm-1946	58	23	syrup	syrup	NOUN
ajlm-1946	58	24	urine	urine	NOUN
ajlm-1946	58	25	disease	disease	NOUN
ajlm-1946	58	26	in	in	ADP
ajlm-1946	58	27	maple	maple	NOUN
ajlm-1946	58	28	syrup	syrup	NOUN
ajlm-1946	58	29	urine	urine	NOUN
ajlm-1946	58	30	disease	disease	NOUN
ajlm-1946	58	31	,	,	PUNCT
ajlm-1946	58	32	there	there	PRON
ajlm-1946	58	33	is	be	VERB
ajlm-1946	58	34	a	a	DET
ajlm-1946	58	35	deficiency	deficiency	NOUN
ajlm-1946	58	36	of	of	ADP
ajlm-1946	58	37	the	the	DET
ajlm-1946	58	38	branched	branched	ADJ
ajlm-1946	58	39	chain	chain	NOUN
ajlm-1946	58	40	α	α	NOUN
ajlm-1946	58	41	-	-	PUNCT
ajlm-1946	58	42	ketoacid	ketoacid	ADJ
ajlm-1946	58	43	dehydrogenase	dehydrogenase	NOUN
ajlm-1946	58	44	enzyme	enzyme	NOUN
ajlm-1946	58	45	that	that	PRON
ajlm-1946	58	46	decarboxylates	decarboxylate	VERB
ajlm-1946	58	47	the	the	DET
ajlm-1946	58	48	branched	branched	ADJ
ajlm-1946	58	49	chain	chain	NOUN
ajlm-1946	58	50	amino	amino	NOUN
ajlm-1946	58	51	acids	acid	NOUN
ajlm-1946	58	52	(	(	PUNCT
ajlm-1946	58	53	leucine	leucine	NOUN
ajlm-1946	58	54	,	,	PUNCT
ajlm-1946	58	55	isoleucine	isoleucine	NOUN
ajlm-1946	58	56	,	,	PUNCT
ajlm-1946	58	57	and	and	CCONJ
ajlm-1946	58	58	valine	valine	NOUN
ajlm-1946	58	59	)	)	PUNCT
ajlm-1946	58	60	.	.	PUNCT
ajlm-1946	59	1	this	this	DET
ajlm-1946	59	2	results	result	NOUN
ajlm-1946	59	3	in	in	ADP
ajlm-1946	59	4	the	the	DET
ajlm-1946	59	5	accumulation	accumulation	NOUN
ajlm-1946	59	6	of	of	ADP
ajlm-1946	59	7	these	these	DET
ajlm-1946	59	8	amino	amino	ADJ
ajlm-1946	59	9	acids	acid	NOUN
ajlm-1946	59	10	and	and	CCONJ
ajlm-1946	59	11	their	their	PRON
ajlm-1946	59	12	metabolites	metabolite	NOUN
ajlm-1946	59	13	(	(	PUNCT
ajlm-1946	59	14	a	a	DET
ajlm-1946	59	15	-	-	PUNCT
ajlm-1946	59	16	ketoacids	ketoacid	NOUN
ajlm-1946	59	17	)	)	PUNCT
ajlm-1946	59	18	in	in	ADP
ajlm-1946	59	19	the	the	DET
ajlm-1946	59	20	blood	blood	NOUN
ajlm-1946	59	21	.	.	PUNCT
ajlm-1946	60	1	maple	maple	NOUN
ajlm-1946	60	2	syrup	syrup	NOUN
ajlm-1946	60	3	urine	urine	NOUN
ajlm-1946	60	4	disease	disease	NOUN
ajlm-1946	60	5	is	be	AUX
ajlm-1946	60	6	a	a	DET
ajlm-1946	60	7	severe	severe	ADJ
ajlm-1946	60	8	iem	iem	NOUN
ajlm-1946	60	9	that	that	PRON
ajlm-1946	60	10	begins	begin	VERB
ajlm-1946	60	11	in	in	ADP
ajlm-1946	60	12	the	the	DET
ajlm-1946	60	13	first	first	ADJ
ajlm-1946	60	14	year	year	NOUN
ajlm-1946	60	15	of	of	ADP
ajlm-1946	60	16	life	life	NOUN
ajlm-1946	60	17	and	and	CCONJ
ajlm-1946	60	18	progresses	progress	NOUN
ajlm-1946	60	19	to	to	ADP
ajlm-1946	60	20	severe	severe	ADJ
ajlm-1946	60	21	mr	mr	PROPN
ajlm-1946	60	22	,	,	PUNCT
ajlm-1946	60	23	acidosis	acidosis	NOUN
ajlm-1946	60	24	,	,	PUNCT
ajlm-1946	60	25	coma	coma	NOUN
ajlm-1946	60	26	,	,	PUNCT
ajlm-1946	60	27	and	and	CCONJ
ajlm-1946	60	28	death	death	NOUN
ajlm-1946	60	29	within	within	ADP
ajlm-1946	60	30	5	5	NUM
ajlm-1946	60	31	years	year	NOUN
ajlm-1946	60	32	if	if	SCONJ
ajlm-1946	60	33	left	leave	VERB
ajlm-1946	60	34	untreated	untreated	ADJ
ajlm-1946	60	35	.	.	PUNCT
ajlm-1946	61	1	as	as	ADP
ajlm-1946	61	2	an	an	DET
ajlm-1946	61	3	alternative	alternative	NOUN
ajlm-1946	61	4	to	to	AUX
ajlm-1946	61	5	tandem	tandem	VERB
ajlm-1946	61	6	mass	mass	ADJ
ajlm-1946	61	7	spectrometry	spectrometry	NOUN
ajlm-1946	61	8	and	and	CCONJ
ajlm-1946	61	9	high	high	ADJ
ajlm-1946	61	10	-	-	PUNCT
ajlm-1946	61	11	performance	performance	NOUN
ajlm-1946	61	12	liquid	liquid	ADJ
ajlm-1946	61	13	chromatography	chromatography	NOUN
ajlm-1946	61	14	analysis	analysis	NOUN
ajlm-1946	61	15	of	of	ADP
ajlm-1946	61	16	organic	organic	ADJ
ajlm-1946	61	17	acids	acid	NOUN
ajlm-1946	61	18	,	,	PUNCT
ajlm-1946	61	19	maple	maple	NOUN
ajlm-1946	61	20	syrup	syrup	NOUN
ajlm-1946	61	21	urine	urine	NOUN
ajlm-1946	61	22	disease	disease	NOUN
ajlm-1946	61	23	can	can	AUX
ajlm-1946	61	24	easily	easily	ADV
ajlm-1946	61	25	be	be	AUX
ajlm-1946	61	26	detected	detect	VERB
ajlm-1946	61	27	in	in	ADP
ajlm-1946	61	28	the	the	DET
ajlm-1946	61	29	laboratory	laboratory	NOUN
ajlm-1946	61	30	using	use	VERB
ajlm-1946	61	31	the	the	DET
ajlm-1946	61	32	rothera	rothera	NOUN
ajlm-1946	61	33	’s	’s	PART
ajlm-1946	61	34	test	test	NOUN
ajlm-1946	61	35	.	.	PUNCT
ajlm-1946	62	1	this	this	PRON
ajlm-1946	62	2	requires	require	VERB
ajlm-1946	62	3	a	a	DET
ajlm-1946	62	4	simple	simple	ADJ
ajlm-1946	62	5	sodium	sodium	NOUN
ajlm-1946	62	6	nitroprusside	nitroprusside	ADP
ajlm-1946	62	7	reagent	reagent	NOUN
ajlm-1946	62	8	(	(	PUNCT
ajlm-1946	62	9	a	a	DET
ajlm-1946	62	10	common	common	ADJ
ajlm-1946	62	11	reagent	reagent	NOUN
ajlm-1946	62	12	in	in	ADP
ajlm-1946	62	13	most	most	ADJ
ajlm-1946	62	14	clinical	clinical	ADJ
ajlm-1946	62	15	chemistry	chemistry	NOUN
ajlm-1946	62	16	laboratories	laboratory	NOUN
ajlm-1946	62	17	)	)	PUNCT
ajlm-1946	62	18	and	and	CCONJ
ajlm-1946	62	19	ammonium	ammonium	NOUN
ajlm-1946	62	20	hydroxide	hydroxide	NOUN
ajlm-1946	62	21	.	.	PUNCT
ajlm-1946	63	1	when	when	SCONJ
ajlm-1946	63	2	mixed	mixed	ADJ
ajlm-1946	63	3	and	and	CCONJ
ajlm-1946	63	4	pulverised	pulverise	VERB
ajlm-1946	63	5	,	,	PUNCT
ajlm-1946	63	6	the	the	DET
ajlm-1946	63	7	test	test	NOUN
ajlm-1946	63	8	retains	retain	VERB
ajlm-1946	63	9	its	its	PRON
ajlm-1946	63	10	positive	positive	ADJ
ajlm-1946	63	11	reaction	reaction	NOUN
ajlm-1946	63	12	,	,	PUNCT
ajlm-1946	63	13	unlike	unlike	ADP
ajlm-1946	63	14	in	in	ADP
ajlm-1946	63	15	cases	case	NOUN
ajlm-1946	63	16	of	of	ADP
ajlm-1946	63	17	metabolic	metabolic	NOUN
ajlm-1946	63	18	derangement	derangement	NOUN
ajlm-1946	63	19	such	such	ADJ
ajlm-1946	63	20	as	as	ADP
ajlm-1946	63	21	type	type	NOUN
ajlm-1946	63	22	1	1	NUM
ajlm-1946	63	23	diabetes	diabetes	NOUN
ajlm-1946	63	24	mellitus	mellitus	NOUN
ajlm-1946	63	25	(	(	PUNCT
ajlm-1946	63	26	diabetes	diabetes	VERB
ajlm-1946	63	27	ketoacidosis	ketoacidosis	NOUN
ajlm-1946	63	28	)	)	PUNCT
ajlm-1946	63	29	,	,	PUNCT
ajlm-1946	63	30	where	where	SCONJ
ajlm-1946	63	31	the	the	DET
ajlm-1946	63	32	ketone	ketone	NOUN
ajlm-1946	63	33	bodies	body	NOUN
ajlm-1946	63	34	(	(	PUNCT
ajlm-1946	63	35	acetoacetate	acetoacetate	NOUN
ajlm-1946	63	36	,	,	PUNCT
ajlm-1946	63	37	acetone	acetone	NOUN
ajlm-1946	63	38	,	,	PUNCT
ajlm-1946	63	39	and	and	CCONJ
ajlm-1946	63	40	3	3	NUM
ajlm-1946	63	41	-	-	PUNCT
ajlm-1946	63	42	hydroxy	hydroxy	VERB
ajlm-1946	63	43	butyrate	butyrate	NOUN
ajlm-1946	63	44	)	)	PUNCT
ajlm-1946	63	45	are	be	AUX
ajlm-1946	63	46	responsible	responsible	ADJ
ajlm-1946	63	47	for	for	ADP
ajlm-1946	63	48	the	the	DET
ajlm-1946	63	49	positive	positive	ADJ
ajlm-1946	63	50	reaction	reaction	NOUN
ajlm-1946	63	51	.	.	PUNCT
ajlm-1946	64	1	the	the	DET
ajlm-1946	64	2	clinical	clinical	ADJ
ajlm-1946	64	3	observation	observation	NOUN
ajlm-1946	64	4	of	of	ADP
ajlm-1946	64	5	the	the	DET
ajlm-1946	64	6	characteristic	characteristic	ADJ
ajlm-1946	64	7	offensive	offensive	ADJ
ajlm-1946	64	8	odour	odour	NOUN
ajlm-1946	64	9	of	of	ADP
ajlm-1946	64	10	the	the	DET
ajlm-1946	64	11	urine	urine	NOUN
ajlm-1946	64	12	(	(	PUNCT
ajlm-1946	64	13	isovaleric	isovaleric	ADJ
ajlm-1946	64	14	aciduria	aciduria	NOUN
ajlm-1946	64	15	)	)	PUNCT
ajlm-1946	64	16	,	,	PUNCT
ajlm-1946	64	17	which	which	PRON
ajlm-1946	64	18	may	may	AUX
ajlm-1946	64	19	be	be	AUX
ajlm-1946	64	20	the	the	DET
ajlm-1946	64	21	first	first	ADJ
ajlm-1946	64	22	suggestive	suggestive	ADJ
ajlm-1946	64	23	sign	sign	NOUN
ajlm-1946	64	24	of	of	ADP
ajlm-1946	64	25	abnormal	abnormal	ADJ
ajlm-1946	64	26	metabolite	metabolite	NOUN
ajlm-1946	64	27	excretion	excretion	NOUN
ajlm-1946	64	28	,	,	PUNCT
ajlm-1946	64	29	may	may	AUX
ajlm-1946	64	30	be	be	AUX
ajlm-1946	64	31	an	an	DET
ajlm-1946	64	32	indication	indication	NOUN
ajlm-1946	64	33	for	for	ADP
ajlm-1946	64	34	this	this	DET
ajlm-1946	64	35	investigation	investigation	NOUN
ajlm-1946	64	36	.	.	PUNCT
ajlm-1946	65	1	alpha-1	alpha-1	NUM
ajlm-1946	65	2	-	-	PUNCT
ajlm-1946	65	3	antitrypsin	antitrypsin	NOUN
ajlm-1946	65	4	deficiency	deficiency	NOUN
ajlm-1946	65	5	another	another	DET
ajlm-1946	65	6	iem	iem	NOUN
ajlm-1946	65	7	that	that	PRON
ajlm-1946	65	8	can	can	AUX
ajlm-1946	65	9	readily	readily	ADV
ajlm-1946	65	10	be	be	AUX
ajlm-1946	65	11	investigated	investigate	VERB
ajlm-1946	65	12	with	with	ADP
ajlm-1946	65	13	the	the	DET
ajlm-1946	65	14	moderate	moderate	ADJ
ajlm-1946	65	15	facilities	facility	NOUN
ajlm-1946	65	16	available	available	ADJ
ajlm-1946	65	17	in	in	ADP
ajlm-1946	65	18	most	most	ADJ
ajlm-1946	65	19	developing	develop	VERB
ajlm-1946	65	20	countries	country	NOUN
ajlm-1946	65	21	,	,	PUNCT
ajlm-1946	65	22	is	be	AUX
ajlm-1946	65	23	alpha-1	alpha-1	NOUN
ajlm-1946	65	24	-	-	PUNCT
ajlm-1946	65	25	antitrypsin	antitrypsin	NOUN
ajlm-1946	65	26	deficiency	deficiency	NOUN
ajlm-1946	65	27	.	.	PUNCT
ajlm-1946	66	1	alpha-1	alpha-1	NUM
ajlm-1946	66	2	-	-	PUNCT
ajlm-1946	66	3	antitrypsin	antitrypsin	NOUN
ajlm-1946	66	4	is	be	AUX
ajlm-1946	66	5	an	an	DET
ajlm-1946	66	6	antiprotease	antiprotease	NOUN
ajlm-1946	66	7	synthesised	synthesise	VERB
ajlm-1946	66	8	in	in	ADP
ajlm-1946	66	9	the	the	DET
ajlm-1946	66	10	liver	liver	NOUN
ajlm-1946	66	11	,	,	PUNCT
ajlm-1946	66	12	and	and	CCONJ
ajlm-1946	66	13	its	its	PRON
ajlm-1946	66	14	deficiency	deficiency	NOUN
ajlm-1946	66	15	arises	arise	VERB
ajlm-1946	66	16	from	from	ADP
ajlm-1946	66	17	point	point	NOUN
ajlm-1946	66	18	mutations	mutation	NOUN
ajlm-1946	66	19	in	in	ADP
ajlm-1946	66	20	the	the	DET
ajlm-1946	66	21	serpina1	serpina1	PROPN
ajlm-1946	66	22	gene	gene	NOUN
ajlm-1946	66	23	(	(	PUNCT
ajlm-1946	66	24	single	single	ADJ
ajlm-1946	66	25	amino	amino	NOUN
ajlm-1946	66	26	acid	acid	NOUN
ajlm-1946	66	27	substitution	substitution	NOUN
ajlm-1946	66	28	)	)	PUNCT
ajlm-1946	66	29	,	,	PUNCT
ajlm-1946	66	30	with	with	ADP
ajlm-1946	66	31	over	over	ADP
ajlm-1946	66	32	70	70	NUM
ajlm-1946	66	33	alleles	allele	NOUN
ajlm-1946	66	34	described.16	described.16	VERB
ajlm-1946	66	35	the	the	DET
ajlm-1946	66	36	normal	normal	ADJ
ajlm-1946	66	37	genotype	genotype	NOUN
ajlm-1946	66	38	is	be	AUX
ajlm-1946	66	39	pimm	pimm	NOUN
ajlm-1946	66	40	,	,	PUNCT
ajlm-1946	66	41	and	and	CCONJ
ajlm-1946	66	42	pimz	pimz	ADJ
ajlm-1946	66	43	is	be	AUX
ajlm-1946	66	44	the	the	DET
ajlm-1946	66	45	heterozygous	heterozygous	ADJ
ajlm-1946	66	46	genotype	genotype	NOUN
ajlm-1946	66	47	for	for	ADP
ajlm-1946	66	48	the	the	DET
ajlm-1946	66	49	z	z	NOUN
ajlm-1946	66	50	gene	gene	NOUN
ajlm-1946	66	51	.	.	PUNCT
ajlm-1946	67	1	alpha-1	alpha-1	NUM
ajlm-1946	67	2	-	-	PUNCT
ajlm-1946	67	3	antitrypsin	antitrypsin	NOUN
ajlm-1946	67	4	deficiency	deficiency	NOUN
ajlm-1946	67	5	frequently	frequently	ADV
ajlm-1946	67	6	arises	arise	VERB
ajlm-1946	67	7	from	from	ADP
ajlm-1946	67	8	pizz	pizz	NOUN
ajlm-1946	67	9	(	(	PUNCT
ajlm-1946	67	10	the	the	DET
ajlm-1946	67	11	homozygous	homozygous	ADJ
ajlm-1946	67	12	genotype	genotype	NOUN
ajlm-1946	67	13	for	for	ADP
ajlm-1946	67	14	the	the	DET
ajlm-1946	67	15	z	z	PROPN
ajlm-1946	67	16	gene).17	gene).17	PROPN
ajlm-1946	67	17	this	this	DET
ajlm-1946	67	18	genetic	genetic	ADJ
ajlm-1946	67	19	defect	defect	NOUN
ajlm-1946	67	20	causes	cause	VERB
ajlm-1946	67	21	the	the	DET
ajlm-1946	67	22	protein	protein	NOUN
ajlm-1946	67	23	to	to	PART
ajlm-1946	67	24	form	form	VERB
ajlm-1946	67	25	aggregates	aggregate	NOUN
ajlm-1946	67	26	in	in	ADP
ajlm-1946	67	27	the	the	DET
ajlm-1946	67	28	liver	liver	NOUN
ajlm-1946	67	29	that	that	PRON
ajlm-1946	67	30	can	can	AUX
ajlm-1946	67	31	not	not	PART
ajlm-1946	67	32	be	be	AUX
ajlm-1946	67	33	excreted	excrete	VERB
ajlm-1946	67	34	,	,	PUNCT
ajlm-1946	67	35	thus	thus	ADV
ajlm-1946	67	36	causing	cause	VERB
ajlm-1946	67	37	liver	liver	NOUN
ajlm-1946	67	38	damage	damage	NOUN
ajlm-1946	67	39	.	.	PUNCT
ajlm-1946	68	1	the	the	DET
ajlm-1946	68	2	absence	absence	NOUN
ajlm-1946	68	3	of	of	ADP
ajlm-1946	68	4	its	its	PRON
ajlm-1946	68	5	antiprotease	antiprotease	NOUN
ajlm-1946	68	6	activity	activity	NOUN
ajlm-1946	68	7	also	also	ADV
ajlm-1946	68	8	causes	cause	VERB
ajlm-1946	68	9	emphysema	emphysema	NOUN
ajlm-1946	68	10	and	and	CCONJ
ajlm-1946	68	11	cirrhosis	cirrhosis	NOUN
ajlm-1946	68	12	in	in	ADP
ajlm-1946	68	13	children	child	NOUN
ajlm-1946	68	14	.	.	PUNCT
ajlm-1946	69	1	although	although	SCONJ
ajlm-1946	69	2	alpha-1	alpha-1	NUM
ajlm-1946	69	3	-	-	PUNCT
ajlm-1946	69	4	antitrypsin	antitrypsin	NOUN
ajlm-1946	69	5	deficiency	deficiency	NOUN
ajlm-1946	69	6	is	be	AUX
ajlm-1946	69	7	commonly	commonly	ADV
ajlm-1946	69	8	investigated	investigate	VERB
ajlm-1946	69	9	using	use	VERB
ajlm-1946	69	10	polymerase	polymerase	NOUN
ajlm-1946	69	11	chain	chain	NOUN
ajlm-1946	69	12	reaction	reaction	NOUN
ajlm-1946	69	13	in	in	ADP
ajlm-1946	69	14	advanced	advanced	ADJ
ajlm-1946	69	15	laboratories	laboratory	NOUN
ajlm-1946	69	16	,	,	PUNCT
ajlm-1946	69	17	the	the	DET
ajlm-1946	69	18	combination	combination	NOUN
ajlm-1946	69	19	of	of	ADP
ajlm-1946	69	20	traditional	traditional	ADJ
ajlm-1946	69	21	liver	liver	NOUN
ajlm-1946	69	22	function	function	NOUN
ajlm-1946	69	23	tests	test	NOUN
ajlm-1946	69	24	and	and	CCONJ
ajlm-1946	69	25	cellulose	cellulose	NOUN
ajlm-1946	69	26	acetate	acetate	NOUN
ajlm-1946	69	27	serum	serum	NOUN
ajlm-1946	69	28	protein	protein	NOUN
ajlm-1946	69	29	electrophoresis	electrophoresis	NOUN
ajlm-1946	69	30	,	,	PUNCT
ajlm-1946	69	31	when	when	SCONJ
ajlm-1946	69	32	the	the	DET
ajlm-1946	69	33	α	α	NOUN
ajlm-1946	69	34	-	-	NOUN
ajlm-1946	69	35	band	band	NOUN
ajlm-1946	69	36	is	be	AUX
ajlm-1946	69	37	either	either	CCONJ
ajlm-1946	69	38	significantly	significantly	ADV
ajlm-1946	69	39	reduced	reduce	VERB
ajlm-1946	69	40	or	or	CCONJ
ajlm-1946	69	41	completely	completely	ADV
ajlm-1946	69	42	absent	absent	ADJ
ajlm-1946	69	43	,	,	PUNCT
ajlm-1946	69	44	is	be	AUX
ajlm-1946	69	45	highly	highly	ADV
ajlm-1946	69	46	suggestive	suggestive	ADJ
ajlm-1946	69	47	.	.	PUNCT
ajlm-1946	70	1	wilson	wilson	PROPN
ajlm-1946	70	2	’s	’s	PART
ajlm-1946	70	3	disease	disease	PROPN
ajlm-1946	70	4	wilson	wilson	PROPN
ajlm-1946	70	5	’s	’s	PART
ajlm-1946	70	6	disease	disease	NOUN
ajlm-1946	70	7	(	(	PUNCT
ajlm-1946	70	8	hepatolenticular	hepatolenticular	ADJ
ajlm-1946	70	9	degeneration	degeneration	NOUN
ajlm-1946	70	10	)	)	PUNCT
ajlm-1946	70	11	is	be	AUX
ajlm-1946	70	12	another	another	DET
ajlm-1946	70	13	iem	iem	NOUN
ajlm-1946	70	14	that	that	PRON
ajlm-1946	70	15	can	can	AUX
ajlm-1946	70	16	easily	easily	ADV
ajlm-1946	70	17	be	be	AUX
ajlm-1946	70	18	investigated	investigate	VERB
ajlm-1946	70	19	in	in	ADP
ajlm-1946	70	20	a	a	DET
ajlm-1946	70	21	basic	basic	ADJ
ajlm-1946	70	22	clinical	clinical	ADJ
ajlm-1946	70	23	laboratory	laboratory	NOUN
ajlm-1946	70	24	.	.	PUNCT
ajlm-1946	71	1	the	the	DET
ajlm-1946	71	2	disease	disease	NOUN
ajlm-1946	71	3	is	be	AUX
ajlm-1946	71	4	due	due	ADJ
ajlm-1946	71	5	to	to	ADP
ajlm-1946	71	6	a	a	DET
ajlm-1946	71	7	mutation	mutation	NOUN
ajlm-1946	71	8	in	in	ADP
ajlm-1946	71	9	the	the	DET
ajlm-1946	71	10	atp7b	atp7b	PROPN
ajlm-1946	71	11	gene	gene	NOUN
ajlm-1946	71	12	,	,	PUNCT
ajlm-1946	71	13	which	which	PRON
ajlm-1946	71	14	encodes	encode	VERB
ajlm-1946	71	15	the	the	DET
ajlm-1946	71	16	copper	copper	NOUN
ajlm-1946	71	17	-	-	PUNCT
ajlm-1946	71	18	transporting	transport	VERB
ajlm-1946	71	19	protein	protein	NOUN
ajlm-1946	71	20	,	,	PUNCT
ajlm-1946	71	21	ceruloplasmin	ceruloplasmin	PROPN
ajlm-1946	71	22	.	.	PUNCT
ajlm-1946	71	23	wilson	wilson	PROPN
ajlm-1946	71	24	’s	’s	PART
ajlm-1946	71	25	disease	disease	NOUN
ajlm-1946	71	26	is	be	AUX
ajlm-1946	71	27	easily	easily	ADV
ajlm-1946	71	28	identified	identify	VERB
ajlm-1946	71	29	by	by	ADP
ajlm-1946	71	30	kayser	kayser	PROPN
ajlm-1946	71	31	fleischer	fleischer	PROPN
ajlm-1946	71	32	’s	’s	PART
ajlm-1946	71	33	rings	ring	NOUN
ajlm-1946	71	34	(	(	PUNCT
ajlm-1946	71	35	almond	almond	NOUN
ajlm-1946	71	36	-	-	PUNCT
ajlm-1946	71	37	coloured	colour	VERB
ajlm-1946	71	38	rings	ring	NOUN
ajlm-1946	71	39	around	around	ADP
ajlm-1946	71	40	the	the	DET
ajlm-1946	71	41	cornea	cornea	NOUN
ajlm-1946	71	42	)	)	PUNCT
ajlm-1946	71	43	.	.	PUNCT
ajlm-1946	72	1	in	in	ADP
ajlm-1946	72	2	the	the	DET
ajlm-1946	72	3	laboratory	laboratory	NOUN
ajlm-1946	72	4	,	,	PUNCT
ajlm-1946	72	5	wilson	wilson	PROPN
ajlm-1946	72	6	’s	’s	PART
ajlm-1946	72	7	disease	disease	NOUN
ajlm-1946	72	8	can	can	AUX
ajlm-1946	72	9	be	be	AUX
ajlm-1946	72	10	diagnosed	diagnose	VERB
ajlm-1946	72	11	by	by	ADP
ajlm-1946	72	12	determining	determine	VERB
ajlm-1946	72	13	serum	serum	NOUN
ajlm-1946	72	14	copper	copper	NOUN
ajlm-1946	72	15	levels	level	NOUN
ajlm-1946	72	16	using	use	VERB
ajlm-1946	72	17	simple	simple	ADJ
ajlm-1946	72	18	flame	flame	ADJ
ajlm-1946	72	19	atomic	atomic	ADJ
ajlm-1946	72	20	absorption	absorption	NOUN
ajlm-1946	72	21	spectrophotometry	spectrophotometry	NOUN
ajlm-1946	72	22	and	and	CCONJ
ajlm-1946	72	23	ceruloplasmin	ceruloplasmin	NOUN
ajlm-1946	72	24	by	by	ADP
ajlm-1946	72	25	standard	standard	ADJ
ajlm-1946	72	26	spectrophotometric	spectrophotometric	ADJ
ajlm-1946	72	27	methods	method	NOUN
ajlm-1946	72	28	.	.	PUNCT
ajlm-1946	73	1	the	the	DET
ajlm-1946	73	2	result	result	NOUN
ajlm-1946	73	3	will	will	AUX
ajlm-1946	73	4	show	show	VERB
ajlm-1946	73	5	low	low	ADJ
ajlm-1946	73	6	ceruloplasmin	ceruloplasmin	NOUN
ajlm-1946	73	7	concentrations	concentration	NOUN
ajlm-1946	73	8	and	and	CCONJ
ajlm-1946	73	9	serum	serum	NOUN
ajlm-1946	73	10	copper	copper	NOUN
ajlm-1946	73	11	levels	level	NOUN
ajlm-1946	73	12	accompanied	accompany	VERB
ajlm-1946	73	13	by	by	ADP
ajlm-1946	73	14	massive	massive	ADJ
ajlm-1946	73	15	copper	copper	NOUN
ajlm-1946	73	16	excretion	excretion	NOUN
ajlm-1946	73	17	in	in	ADP
ajlm-1946	73	18	the	the	DET
ajlm-1946	73	19	urine	urine	NOUN
ajlm-1946	73	20	.	.	PUNCT
ajlm-1946	74	1	if	if	SCONJ
ajlm-1946	74	2	necessary	necessary	ADJ
ajlm-1946	74	3	,	,	PUNCT
ajlm-1946	74	4	a	a	DET
ajlm-1946	74	5	liver	liver	NOUN
ajlm-1946	74	6	biopsy	biopsy	NOUN
ajlm-1946	74	7	can	can	AUX
ajlm-1946	74	8	be	be	AUX
ajlm-1946	74	9	done	do	VERB
ajlm-1946	74	10	to	to	PART
ajlm-1946	74	11	detect	detect	VERB
ajlm-1946	74	12	excessive	excessive	ADJ
ajlm-1946	74	13	amounts	amount	NOUN
ajlm-1946	74	14	of	of	ADP
ajlm-1946	74	15	copper	copper	NOUN
ajlm-1946	74	16	in	in	ADP
ajlm-1946	74	17	the	the	DET
ajlm-1946	74	18	liver	liver	NOUN
ajlm-1946	74	19	.	.	PUNCT
ajlm-1946	75	1	cystic	cystic	ADJ
ajlm-1946	75	2	fibrosis	fibrosis	NOUN
ajlm-1946	75	3	cystic	cystic	ADJ
ajlm-1946	75	4	fibrosis	fibrosis	NOUN
ajlm-1946	75	5	is	be	AUX
ajlm-1946	75	6	a	a	DET
ajlm-1946	75	7	common	common	ADJ
ajlm-1946	75	8	iem	iem	NOUN
ajlm-1946	75	9	that	that	PRON
ajlm-1946	75	10	affects	affect	VERB
ajlm-1946	75	11	one	one	NUM
ajlm-1946	75	12	out	out	ADP
ajlm-1946	75	13	of	of	ADP
ajlm-1946	75	14	every	every	DET
ajlm-1946	75	15	2500	2500	NUM
ajlm-1946	75	16	live	live	ADJ
ajlm-1946	75	17	births	birth	NOUN
ajlm-1946	75	18	in	in	ADP
ajlm-1946	75	19	the	the	DET
ajlm-1946	75	20	united	united	PROPN
ajlm-1946	75	21	kingdom.18	kingdom.18	PROPN
ajlm-1946	75	22	cystic	cystic	ADJ
ajlm-1946	75	23	fibrosis	fibrosis	NOUN
ajlm-1946	75	24	is	be	AUX
ajlm-1946	75	25	inherited	inherit	VERB
ajlm-1946	75	26	in	in	ADP
ajlm-1946	75	27	a	a	DET
ajlm-1946	75	28	recessive	recessive	ADJ
ajlm-1946	75	29	mendelian	mendelian	ADJ
ajlm-1946	75	30	pattern	pattern	NOUN
ajlm-1946	75	31	,	,	PUNCT
ajlm-1946	75	32	and	and	CCONJ
ajlm-1946	75	33	individuals	individual	NOUN
ajlm-1946	75	34	with	with	ADP
ajlm-1946	75	35	this	this	DET
ajlm-1946	75	36	disease	disease	NOUN
ajlm-1946	75	37	experience	experience	VERB
ajlm-1946	75	38	a	a	DET
ajlm-1946	75	39	generalised	generalised	ADJ
ajlm-1946	75	40	exocrine	exocrine	NOUN
ajlm-1946	75	41	secretion	secretion	NOUN
ajlm-1946	75	42	disorder	disorder	NOUN
ajlm-1946	75	43	that	that	PRON
ajlm-1946	75	44	is	be	AUX
ajlm-1946	75	45	characterised	characterise	VERB
ajlm-1946	75	46	by	by	ADP
ajlm-1946	75	47	abnormally	abnormally	ADV
ajlm-1946	75	48	viscous	viscous	ADJ
ajlm-1946	75	49	secretions	secretion	NOUN
ajlm-1946	75	50	.	.	PUNCT
ajlm-1946	76	1	the	the	DET
ajlm-1946	76	2	functional	functional	ADJ
ajlm-1946	76	3	defect	defect	NOUN
ajlm-1946	76	4	is	be	AUX
ajlm-1946	76	5	caused	cause	VERB
ajlm-1946	76	6	by	by	ADP
ajlm-1946	76	7	the	the	DET
ajlm-1946	76	8	cystic	cystic	ADJ
ajlm-1946	76	9	fibrosis	fibrosis	NOUN
ajlm-1946	76	10	transmembrane	transmembrane	NOUN
ajlm-1946	76	11	conductance	conductance	NOUN
ajlm-1946	76	12	regulator	regulator	NOUN
ajlm-1946	76	13	protein	protein	NOUN
ajlm-1946	76	14	,	,	PUNCT
ajlm-1946	76	15	which	which	PRON
ajlm-1946	76	16	controls	control	VERB
ajlm-1946	76	17	transmembrane	transmembrane	ADJ
ajlm-1946	76	18	chloride	chloride	NOUN
ajlm-1946	76	19	transport.19	transport.19	NOUN
ajlm-1946	76	20	surprisingly	surprisingly	ADV
ajlm-1946	76	21	,	,	PUNCT
ajlm-1946	76	22	cystic	cystic	ADJ
ajlm-1946	76	23	fibrosis	fibrosis	NOUN
ajlm-1946	76	24	patients	patient	NOUN
ajlm-1946	76	25	who	who	PRON
ajlm-1946	76	26	do	do	AUX
ajlm-1946	76	27	not	not	PART
ajlm-1946	76	28	have	have	VERB
ajlm-1946	76	29	functional	functional	ADJ
ajlm-1946	76	30	copies	copy	NOUN
ajlm-1946	76	31	of	of	ADP
ajlm-1946	76	32	the	the	DET
ajlm-1946	76	33	protein	protein	NOUN
ajlm-1946	76	34	have	have	VERB
ajlm-1946	76	35	a	a	DET
ajlm-1946	76	36	slew	slew	NOUN
ajlm-1946	76	37	of	of	ADP
ajlm-1946	76	38	lung	lung	NOUN
ajlm-1946	76	39	and	and	CCONJ
ajlm-1946	76	40	digestive	digestive	ADJ
ajlm-1946	76	41	problems.20	problems.20	NOUN
ajlm-1946	76	42	symptoms	symptom	NOUN
ajlm-1946	76	43	include	include	VERB
ajlm-1946	76	44	recurrent	recurrent	ADJ
ajlm-1946	76	45	respiratory	respiratory	ADJ
ajlm-1946	76	46	infections	infection	NOUN
ajlm-1946	76	47	,	,	PUNCT
ajlm-1946	76	48	irreversible	irreversible	ADJ
ajlm-1946	76	49	lung	lung	NOUN
ajlm-1946	76	50	disease	disease	NOUN
ajlm-1946	76	51	,	,	PUNCT
ajlm-1946	76	52	and	and	CCONJ
ajlm-1946	76	53	pancreatic	pancreatic	ADJ
ajlm-1946	76	54	insufficiency	insufficiency	NOUN
ajlm-1946	76	55	leading	lead	VERB
ajlm-1946	76	56	to	to	ADP
ajlm-1946	76	57	malabsorption	malabsorption	NOUN
ajlm-1946	76	58	.	.	PUNCT
ajlm-1946	77	1	in	in	ADP
ajlm-1946	77	2	neonates	neonate	NOUN
ajlm-1946	77	3	,	,	PUNCT
ajlm-1946	77	4	intestinal	intestinal	ADJ
ajlm-1946	77	5	obstruction	obstruction	NOUN
ajlm-1946	77	6	can	can	AUX
ajlm-1946	77	7	occur	occur	VERB
ajlm-1946	77	8	due	due	ADP
ajlm-1946	77	9	to	to	ADP
ajlm-1946	77	10	the	the	DET
ajlm-1946	77	11	increased	increase	VERB
ajlm-1946	77	12	viscosity	viscosity	NOUN
ajlm-1946	77	13	of	of	ADP
ajlm-1946	77	14	faecal	faecal	ADJ
ajlm-1946	77	15	material	material	NOUN
ajlm-1946	77	16	,	,	PUNCT
ajlm-1946	77	17	which	which	PRON
ajlm-1946	77	18	is	be	AUX
ajlm-1946	77	19	useful	useful	ADJ
ajlm-1946	77	20	in	in	ADP
ajlm-1946	77	21	laboratories	laboratory	NOUN
ajlm-1946	77	22	for	for	ADP
ajlm-1946	77	23	disease	disease	NOUN
ajlm-1946	77	24	screening	screen	VERB
ajlm-1946	77	25	.	.	PUNCT
ajlm-1946	78	1	cystic	cystic	ADJ
ajlm-1946	78	2	fibrosis	fibrosis	NOUN
ajlm-1946	78	3	can	can	AUX
ajlm-1946	78	4	be	be	AUX
ajlm-1946	78	5	identified	identify	VERB
ajlm-1946	78	6	clinically	clinically	ADV
ajlm-1946	78	7	through	through	ADP
ajlm-1946	78	8	slit	slit	ADJ
ajlm-1946	78	9	-	-	PUNCT
ajlm-1946	78	10	lamp	lamp	NOUN
ajlm-1946	78	11	examination	examination	NOUN
ajlm-1946	78	12	of	of	ADP
ajlm-1946	78	13	affected	affected	ADJ
ajlm-1946	78	14	patients	patient	NOUN
ajlm-1946	78	15	’	'	PUNCT
ajlm-1946	78	16	eyes	eye	NOUN
ajlm-1946	78	17	,	,	PUNCT
ajlm-1946	78	18	which	which	PRON
ajlm-1946	78	19	may	may	AUX
ajlm-1946	78	20	reveal	reveal	VERB
ajlm-1946	78	21	pathognomonic	pathognomonic	ADJ
ajlm-1946	78	22	crystals	crystal	NOUN
ajlm-1946	78	23	of	of	ADP
ajlm-1946	78	24	cystine	cystine	NOUN
ajlm-1946	78	25	in	in	ADP
ajlm-1946	78	26	the	the	DET
ajlm-1946	78	27	cornea	cornea	NOUN
ajlm-1946	78	28	.	.	PUNCT
ajlm-1946	79	1	this	this	DET
ajlm-1946	79	2	corneal	corneal	ADJ
ajlm-1946	79	3	defect	defect	NOUN
ajlm-1946	79	4	can	can	AUX
ajlm-1946	79	5	cause	cause	VERB
ajlm-1946	79	6	photophobia	photophobia	NOUN
ajlm-1946	79	7	,	,	PUNCT
ajlm-1946	79	8	beginning	begin	VERB
ajlm-1946	79	9	around	around	ADP
ajlm-1946	79	10	the	the	DET
ajlm-1946	79	11	age	age	NOUN
ajlm-1946	79	12	of	of	ADP
ajlm-1946	79	13	two	two	NUM
ajlm-1946	79	14	.	.	PUNCT
ajlm-1946	80	1	cystic	cystic	ADJ
ajlm-1946	80	2	fibrosis	fibrosis	NOUN
ajlm-1946	80	3	can	can	AUX
ajlm-1946	80	4	be	be	AUX
ajlm-1946	80	5	screened	screen	VERB
ajlm-1946	80	6	for	for	ADP
ajlm-1946	80	7	using	use	VERB
ajlm-1946	80	8	immunoreactive	immunoreactive	ADJ
ajlm-1946	80	9	trypsin	trypsin	NOUN
ajlm-1946	80	10	in	in	ADP
ajlm-1946	80	11	blood	blood	NOUN
ajlm-1946	80	12	.	.	PUNCT
ajlm-1946	81	1	also	also	ADV
ajlm-1946	81	2	,	,	PUNCT
ajlm-1946	81	3	faecal	faecal	ADJ
ajlm-1946	81	4	pancreatic	pancreatic	NOUN
ajlm-1946	81	5	elastase-1	elastase-1	PROPN
ajlm-1946	81	6	is	be	AUX
ajlm-1946	81	7	the	the	DET
ajlm-1946	81	8	most	most	ADV
ajlm-1946	81	9	widely	widely	ADV
ajlm-1946	81	10	used	use	VERB
ajlm-1946	81	11	test	test	NOUN
ajlm-1946	81	12	to	to	PART
ajlm-1946	81	13	diagnose	diagnose	VERB
ajlm-1946	81	14	pancreatic	pancreatic	ADJ
ajlm-1946	81	15	insufficiency	insufficiency	NOUN
ajlm-1946	81	16	in	in	ADP
ajlm-1946	81	17	people	people	NOUN
ajlm-1946	81	18	with	with	ADP
ajlm-1946	81	19	cystic	cystic	ADJ
ajlm-1946	81	20	fibrosis	fibrosis	NOUN
ajlm-1946	81	21	.	.	PUNCT
ajlm-1946	82	1	sweat	sweat	NOUN
ajlm-1946	82	2	electrolyte	electrolyte	ADJ
ajlm-1946	82	3	analysis	analysis	NOUN
ajlm-1946	82	4	is	be	AUX
ajlm-1946	82	5	used	use	VERB
ajlm-1946	82	6	to	to	PART
ajlm-1946	82	7	make	make	VERB
ajlm-1946	82	8	the	the	DET
ajlm-1946	82	9	final	final	ADJ
ajlm-1946	82	10	diagnosis	diagnosis	NOUN
ajlm-1946	82	11	;	;	PUNCT
ajlm-1946	82	12	when	when	SCONJ
ajlm-1946	82	13	sweat	sweat	NOUN
ajlm-1946	82	14	chloride	chloride	NOUN
ajlm-1946	82	15	level	level	NOUN
ajlm-1946	82	16	is	be	AUX
ajlm-1946	82	17	less	less	ADJ
ajlm-1946	82	18	than	than	ADP
ajlm-1946	82	19	30	30	NUM
ajlm-1946	82	20	mmol	mmol	NOUN
ajlm-1946	82	21	/	/	SYM
ajlm-1946	82	22	l	l	NOUN
ajlm-1946	82	23	,	,	PUNCT
ajlm-1946	82	24	cystic	cystic	ADJ
ajlm-1946	82	25	fibrosis	fibrosis	NOUN
ajlm-1946	82	26	is	be	AUX
ajlm-1946	82	27	not	not	PART
ajlm-1946	82	28	likely	likely	ADJ
ajlm-1946	82	29	,	,	PUNCT
ajlm-1946	82	30	but	but	CCONJ
ajlm-1946	82	31	when	when	SCONJ
ajlm-1946	82	32	it	it	PRON
ajlm-1946	82	33	is	be	AUX
ajlm-1946	82	34	greater	great	ADJ
ajlm-1946	82	35	than	than	ADP
ajlm-1946	82	36	or	or	CCONJ
ajlm-1946	82	37	equal	equal	ADJ
ajlm-1946	82	38	to	to	ADP
ajlm-1946	82	39	60	60	NUM
ajlm-1946	82	40	mmol	mmol	NOUN
ajlm-1946	82	41	/	/	SYM
ajlm-1946	82	42	l	l	NOUN
ajlm-1946	82	43	,	,	PUNCT
ajlm-1946	82	44	it	it	PRON
ajlm-1946	82	45	is	be	AUX
ajlm-1946	82	46	diagnostic.21	diagnostic.21	ADJ
ajlm-1946	82	47	pilocarpine	pilocarpine	NOUN
ajlm-1946	82	48	iontophoresis	iontophoresis	NOUN
ajlm-1946	82	49	(	(	PUNCT
ajlm-1946	82	50	using	use	VERB
ajlm-1946	82	51	an	an	DET
ajlm-1946	82	52	electric	electric	ADJ
ajlm-1946	82	53	device	device	NOUN
ajlm-1946	82	54	to	to	PART
ajlm-1946	82	55	stimulate	stimulate	VERB
ajlm-1946	82	56	sweating	sweating	NOUN
ajlm-1946	82	57	)	)	PUNCT
ajlm-1946	82	58	is	be	AUX
ajlm-1946	82	59	also	also	ADV
ajlm-1946	82	60	a	a	DET
ajlm-1946	82	61	standard	standard	ADJ
ajlm-1946	82	62	test	test	NOUN
ajlm-1946	82	63	used	use	VERB
ajlm-1946	82	64	in	in	ADP
ajlm-1946	82	65	the	the	DET
ajlm-1946	82	66	diagnosis	diagnosis	NOUN
ajlm-1946	82	67	of	of	ADP
ajlm-1946	82	68	cystic	cystic	ADJ
ajlm-1946	82	69	fibrosis	fibrosis	NOUN
ajlm-1946	82	70	.	.	PUNCT
ajlm-1946	83	1	galactosaemia	galactosaemia	NOUN
ajlm-1946	83	2	galactosaemia	galactosaemia	PROPN
ajlm-1946	83	3	is	be	AUX
ajlm-1946	83	4	caused	cause	VERB
ajlm-1946	83	5	by	by	ADP
ajlm-1946	83	6	a	a	DET
ajlm-1946	83	7	lack	lack	NOUN
ajlm-1946	83	8	of	of	ADP
ajlm-1946	83	9	galactose-1	galactose-1	NOUN
ajlm-1946	83	10	-	-	PUNCT
ajlm-1946	83	11	phosphate	phosphate	NOUN
ajlm-1946	83	12	uridyltransferase	uridyltransferase	NOUN
ajlm-1946	83	13	,	,	PUNCT
ajlm-1946	83	14	a	a	DET
ajlm-1946	83	15	rate	rate	NOUN
ajlm-1946	83	16	-	-	PUNCT
ajlm-1946	83	17	limiting	limit	VERB
ajlm-1946	83	18	enzyme	enzyme	NOUN
ajlm-1946	83	19	that	that	PRON
ajlm-1946	83	20	causes	cause	VERB
ajlm-1946	83	21	hypoglycaemia	hypoglycaemia	NOUN
ajlm-1946	83	22	.	.	PUNCT
ajlm-1946	84	1	this	this	PRON
ajlm-1946	84	2	leads	lead	VERB
ajlm-1946	84	3	to	to	ADP
ajlm-1946	84	4	increased	increase	VERB
ajlm-1946	84	5	levels	level	NOUN
ajlm-1946	84	6	of	of	ADP
ajlm-1946	84	7	galactose-1	galactose-1	NOUN
ajlm-1946	84	8	-	-	PUNCT
ajlm-1946	84	9	phosphate	phosphate	NOUN
ajlm-1946	84	10	due	due	ADP
ajlm-1946	84	11	to	to	ADP
ajlm-1946	84	12	blockage	blockage	NOUN
ajlm-1946	84	13	of	of	ADP
ajlm-1946	84	14	the	the	DET
ajlm-1946	84	15	typical	typical	ADJ
ajlm-1946	84	16	metabolic	metabolic	NOUN
ajlm-1946	84	17	pathway	pathway	NOUN
ajlm-1946	84	18	,	,	PUNCT
ajlm-1946	84	19	and	and	CCONJ
ajlm-1946	84	20	this	this	PRON
ajlm-1946	84	21	may	may	AUX
ajlm-1946	84	22	lead	lead	VERB
ajlm-1946	84	23	to	to	ADP
ajlm-1946	84	24	alternative	alternative	ADJ
ajlm-1946	84	25	metabolism	metabolism	NOUN
ajlm-1946	84	26	and	and	CCONJ
ajlm-1946	84	27	direct	direct	ADJ
ajlm-1946	84	28	tissue	tissue	NOUN
ajlm-1946	84	29	damage	damage	NOUN
ajlm-1946	84	30	.	.	PUNCT
ajlm-1946	85	1	some	some	DET
ajlm-1946	85	2	key	key	ADJ
ajlm-1946	85	3	biochemical	biochemical	ADJ
ajlm-1946	85	4	features	feature	NOUN
ajlm-1946	85	5	of	of	ADP
ajlm-1946	85	6	galactosaemia	galactosaemia	NOUN
ajlm-1946	85	7	include	include	VERB
ajlm-1946	85	8	impaired	impaired	ADJ
ajlm-1946	85	9	bilirubin	bilirubin	NOUN
ajlm-1946	85	10	uptake	uptake	NOUN
ajlm-1946	85	11	and	and	CCONJ
ajlm-1946	85	12	conjugation	conjugation	NOUN
ajlm-1946	85	13	,	,	PUNCT
ajlm-1946	85	14	increased	increase	VERB
ajlm-1946	85	15	unconjugated	unconjugated	ADJ
ajlm-1946	85	16	hyperbilirubinemia	hyperbilirubinemia	NOUN
ajlm-1946	85	17	,	,	PUNCT
ajlm-1946	85	18	hepatomegaly	hepatomegaly	NOUN
ajlm-1946	85	19	,	,	PUNCT
ajlm-1946	85	20	jaundice	jaundice	NOUN
ajlm-1946	85	21	,	,	PUNCT
ajlm-1946	85	22	severe	severe	ADJ
ajlm-1946	85	23	mr	mr	PROPN
ajlm-1946	85	24	,	,	PUNCT
ajlm-1946	85	25	accumulation	accumulation	NOUN
ajlm-1946	85	26	of	of	ADP
ajlm-1946	85	27	free	free	ADJ
ajlm-1946	85	28	galactose	galactose	NOUN
ajlm-1946	85	29	,	,	PUNCT
ajlm-1946	85	30	and	and	CCONJ
ajlm-1946	85	31	deposition	deposition	NOUN
ajlm-1946	85	32	of	of	ADP
ajlm-1946	85	33	galactose-1	galactose-1	NOUN
ajlm-1946	85	34	-	-	PUNCT
ajlm-1946	85	35	phosphate	phosphate	NOUN
ajlm-1946	85	36	in	in	ADP
ajlm-1946	85	37	renal	renal	ADJ
ajlm-1946	85	38	tubules	tubule	NOUN
ajlm-1946	85	39	with	with	ADP
ajlm-1946	85	40	attendant	attendant	ADJ
ajlm-1946	85	41	renal	renal	ADJ
ajlm-1946	85	42	damage	damage	NOUN
ajlm-1946	85	43	and	and	CCONJ
ajlm-1946	85	44	associated	associate	VERB
ajlm-1946	85	45	generalised	generalise	VERB
ajlm-1946	85	46	aminoaciduria	aminoaciduria	NOUN
ajlm-1946	85	47	.	.	PUNCT
ajlm-1946	86	1	simple	simple	ADJ
ajlm-1946	86	2	and	and	CCONJ
ajlm-1946	86	3	practical	practical	ADJ
ajlm-1946	86	4	tests	test	NOUN
ajlm-1946	86	5	that	that	PRON
ajlm-1946	86	6	can	can	AUX
ajlm-1946	86	7	be	be	AUX
ajlm-1946	86	8	used	use	VERB
ajlm-1946	86	9	to	to	PART
ajlm-1946	86	10	investigate	investigate	VERB
ajlm-1946	86	11	galactosaemia	galactosaemia	NOUN
ajlm-1946	86	12	include	include	VERB
ajlm-1946	86	13	benedict	benedict	PROPN
ajlm-1946	86	14	’s	’s	PART
ajlm-1946	86	15	test	test	NOUN
ajlm-1946	86	16	to	to	PART
ajlm-1946	86	17	detect	detect	VERB
ajlm-1946	86	18	the	the	DET
ajlm-1946	86	19	presence	presence	NOUN
ajlm-1946	86	20	of	of	ADP
ajlm-1946	86	21	reducing	reduce	VERB
ajlm-1946	86	22	substances	substance	NOUN
ajlm-1946	86	23	,	,	PUNCT
ajlm-1946	86	24	thin	thin	ADJ
ajlm-1946	86	25	-	-	PUNCT
ajlm-1946	86	26	layer	layer	NOUN
ajlm-1946	86	27	chromatography	chromatography	NOUN
ajlm-1946	86	28	to	to	PART
ajlm-1946	86	29	determine	determine	VERB
ajlm-1946	86	30	the	the	DET
ajlm-1946	86	31	presence	presence	NOUN
ajlm-1946	86	32	of	of	ADP
ajlm-1946	86	33	galactose	galactose	NOUN
ajlm-1946	86	34	in	in	ADP
ajlm-1946	86	35	urine	urine	NOUN
ajlm-1946	86	36	,	,	PUNCT
ajlm-1946	86	37	and	and	CCONJ
ajlm-1946	86	38	galactose-1	galactose-1	NOUN
ajlm-1946	86	39	-	-	PUNCT
ajlm-1946	86	40	phosphate	phosphate	ADJ
ajlm-1946	86	41	uridyltransferase	uridyltransferase	NOUN
ajlm-1946	86	42	enzyme	enzyme	NOUN
ajlm-1946	86	43	assay	assay	VERB
ajlm-1946	86	44	to	to	PART
ajlm-1946	86	45	detect	detect	VERB
ajlm-1946	86	46	elevated	elevated	ADJ
ajlm-1946	86	47	blood	blood	NOUN
ajlm-1946	86	48	galactose	galactose	NOUN
ajlm-1946	86	49	.	.	PUNCT
ajlm-1946	87	1	amniocentesis	amniocentesis	NOUN
ajlm-1946	87	2	may	may	AUX
ajlm-1946	87	3	be	be	AUX
ajlm-1946	87	4	used	use	VERB
ajlm-1946	87	5	for	for	ADP
ajlm-1946	87	6	prenatal	prenatal	ADJ
ajlm-1946	87	7	diagnosis	diagnosis	NOUN
ajlm-1946	87	8	,	,	PUNCT
ajlm-1946	87	9	and	and	CCONJ
ajlm-1946	87	10	the	the	DET
ajlm-1946	87	11	galactose	galactose	ADJ
ajlm-1946	87	12	tolerance	tolerance	NOUN
ajlm-1946	87	13	test	test	NOUN
ajlm-1946	87	14	may	may	AUX
ajlm-1946	87	15	be	be	AUX
ajlm-1946	87	16	performed	perform	VERB
ajlm-1946	87	17	if	if	SCONJ
ajlm-1946	87	18	the	the	DET
ajlm-1946	87	19	expected	expect	VERB
ajlm-1946	87	20	rise	rise	NOUN
ajlm-1946	87	21	in	in	ADP
ajlm-1946	87	22	the	the	DET
ajlm-1946	87	23	blood	blood	NOUN
ajlm-1946	87	24	glucose	glucose	NOUN
ajlm-1946	87	25	level	level	NOUN
ajlm-1946	87	26	after	after	SCONJ
ajlm-1946	87	27	galactose	galactose	ADJ
ajlm-1946	87	28	administration	administration	NOUN
ajlm-1946	87	29	is	be	AUX
ajlm-1946	87	30	not	not	PART
ajlm-1946	87	31	observed	observe	VERB
ajlm-1946	87	32	.	.	PUNCT
ajlm-1946	88	1	in	in	ADP
ajlm-1946	88	2	advanced	advanced	ADJ
ajlm-1946	88	3	laboratories	laboratory	NOUN
ajlm-1946	88	4	,	,	PUNCT
ajlm-1946	88	5	molecular	molecular	ADJ
ajlm-1946	88	6	analysis	analysis	NOUN
ajlm-1946	88	7	is	be	AUX
ajlm-1946	88	8	available.22	available.22	NOUN
ajlm-1946	88	9	the	the	DET
ajlm-1946	88	10	diagnosis	diagnosis	NOUN
ajlm-1946	88	11	of	of	ADP
ajlm-1946	88	12	galactosaemia	galactosaemia	NOUN
ajlm-1946	88	13	is	be	AUX
ajlm-1946	88	14	well	well	ADV
ajlm-1946	88	15	within	within	ADP
ajlm-1946	88	16	the	the	DET
ajlm-1946	88	17	capabilities	capability	NOUN
ajlm-1946	88	18	of	of	ADP
ajlm-1946	88	19	most	most	ADJ
ajlm-1946	88	20	basic	basic	ADJ
ajlm-1946	88	21	medical	medical	ADJ
ajlm-1946	88	22	facilities	facility	NOUN
ajlm-1946	88	23	and	and	CCONJ
ajlm-1946	88	24	the	the	DET
ajlm-1946	88	25	treatment	treatment	NOUN
ajlm-1946	88	26	is	be	AUX
ajlm-1946	88	27	simple	simple	ADJ
ajlm-1946	88	28	,	,	PUNCT
ajlm-1946	88	29	only	only	ADV
ajlm-1946	88	30	requiring	require	VERB
ajlm-1946	88	31	the	the	DET
ajlm-1946	88	32	elimination	elimination	NOUN
ajlm-1946	88	33	of	of	ADP
ajlm-1946	88	34	galactose	galactose	NOUN
ajlm-1946	88	35	from	from	ADP
ajlm-1946	88	36	the	the	DET
ajlm-1946	88	37	diet	diet	NOUN
ajlm-1946	88	38	.	.	PUNCT
ajlm-1946	89	1	von	von	PROPN
ajlm-1946	89	2	gierke	gierke	PROPN
ajlm-1946	89	3	’s	’s	PART
ajlm-1946	89	4	disease	disease	NOUN
ajlm-1946	89	5	in	in	ADP
ajlm-1946	89	6	von	von	PROPN
ajlm-1946	89	7	gierke	gierke	PROPN
ajlm-1946	89	8	’s	’s	PART
ajlm-1946	89	9	disease	disease	NOUN
ajlm-1946	89	10	,	,	PUNCT
ajlm-1946	89	11	there	there	PRON
ajlm-1946	89	12	is	be	VERB
ajlm-1946	89	13	deficiency	deficiency	NOUN
ajlm-1946	89	14	of	of	ADP
ajlm-1946	89	15	glucose-6	glucose-6	NOUN
ajlm-1946	89	16	-	-	NOUN
ajlm-1946	89	17	phosphatase	phosphatase	NOUN
ajlm-1946	89	18	,	,	PUNCT
ajlm-1946	89	19	an	an	DET
ajlm-1946	89	20	enzyme	enzyme	NOUN
ajlm-1946	89	21	that	that	PRON
ajlm-1946	89	22	splits	split	VERB
ajlm-1946	89	23	glucose	glucose	NOUN
ajlm-1946	89	24	from	from	ADP
ajlm-1946	89	25	glucose-6	glucose-6	NOUN
ajlm-1946	89	26	-	-	PUNCT
ajlm-1946	89	27	phosphate	phosphate	NOUN
ajlm-1946	89	28	(	(	PUNCT
ajlm-1946	89	29	glucose-6	glucose-6	PROPN
ajlm-1946	89	30	-	-	PUNCT
ajlm-1946	89	31	po4	po4	PROPN
ajlm-1946	89	32	+	+	CCONJ
ajlm-1946	89	33	g-6	g-6	NOUN
ajlm-1946	89	34	-	-	PUNCT
ajlm-1946	89	35	phosphatase	phosphatase	NOUN
ajlm-1946	89	36	→	→	SYM
ajlm-1946	89	37	glucose	glucose	NOUN
ajlm-1946	89	38	+	+	CCONJ
ajlm-1946	89	39	po4	po4	NOUN
ajlm-1946	89	40	)	)	PUNCT
ajlm-1946	89	41	.	.	PUNCT
ajlm-1946	90	1	owing	owe	VERB
ajlm-1946	90	2	to	to	ADP
ajlm-1946	90	3	this	this	DET
ajlm-1946	90	4	metabolic	metabolic	NOUN
ajlm-1946	90	5	block	block	NOUN
ajlm-1946	90	6	,	,	PUNCT
ajlm-1946	90	7	glucose-6	glucose-6	NOUN
ajlm-1946	90	8	-	-	PUNCT
ajlm-1946	90	9	phosphate	phosphate	NOUN
ajlm-1946	90	10	accumulates	accumulate	VERB
ajlm-1946	90	11	in	in	ADP
ajlm-1946	90	12	the	the	DET
ajlm-1946	90	13	liver	liver	NOUN
ajlm-1946	90	14	.	.	PUNCT
ajlm-1946	91	1	the	the	DET
ajlm-1946	91	2	presence	presence	NOUN
ajlm-1946	91	3	of	of	ADP
ajlm-1946	91	4	fasting	fast	VERB
ajlm-1946	91	5	hypoglycaemia	hypoglycaemia	NOUN
ajlm-1946	91	6	and	and	CCONJ
ajlm-1946	91	7	hepatomegaly	hepatomegaly	NOUN
ajlm-1946	91	8	are	be	AUX
ajlm-1946	91	9	strongly	strongly	ADV
ajlm-1946	91	10	suggestive	suggestive	ADJ
ajlm-1946	91	11	of	of	ADP
ajlm-1946	91	12	von	von	PROPN
ajlm-1946	91	13	gierke	gierke	PROPN
ajlm-1946	91	14	’s	’s	PART
ajlm-1946	91	15	disease	disease	NOUN
ajlm-1946	91	16	and	and	CCONJ
ajlm-1946	91	17	clearly	clearly	ADV
ajlm-1946	91	18	distinguishes	distinguish	VERB
ajlm-1946	91	19	it	it	PRON
ajlm-1946	91	20	from	from	ADP
ajlm-1946	91	21	other	other	ADJ
ajlm-1946	91	22	glycogenoses	glycogenose	NOUN
ajlm-1946	91	23	such	such	ADJ
ajlm-1946	91	24	as	as	ADP
ajlm-1946	91	25	pompe	pompe	PROPN
ajlm-1946	91	26	’s	’s	PROPN
ajlm-1946	91	27	,	,	PUNCT
ajlm-1946	91	28	mcardle	mcardle	PROPN
ajlm-1946	91	29	’s	’s	PART
ajlm-1946	91	30	,	,	PUNCT
ajlm-1946	91	31	and	and	CCONJ
ajlm-1946	91	32	many	many	ADJ
ajlm-1946	91	33	others	other	NOUN
ajlm-1946	91	34	.	.	PUNCT
ajlm-1946	92	1	urea	urea	NOUN
ajlm-1946	92	2	cycle	cycle	NOUN
ajlm-1946	92	3	disorders	disorder	NOUN
ajlm-1946	92	4	type	type	VERB
ajlm-1946	92	5	1	1	NUM
ajlm-1946	92	6	hyperammonaemia	hyperammonaemia	NOUN
ajlm-1946	92	7	type	type	NOUN
ajlm-1946	92	8	1	1	NUM
ajlm-1946	92	9	hyperammonaemia	hyperammonaemia	NOUN
ajlm-1946	92	10	is	be	AUX
ajlm-1946	92	11	one	one	NUM
ajlm-1946	92	12	of	of	ADP
ajlm-1946	92	13	the	the	DET
ajlm-1946	92	14	common	common	ADJ
ajlm-1946	92	15	urea	urea	NOUN
ajlm-1946	92	16	cycle	cycle	NOUN
ajlm-1946	92	17	disorders	disorder	NOUN
ajlm-1946	92	18	(	(	PUNCT
ajlm-1946	92	19	ucds	ucds	NOUN
ajlm-1946	92	20	)	)	PUNCT
ajlm-1946	92	21	.	.	PUNCT
ajlm-1946	93	1	it	it	PRON
ajlm-1946	93	2	is	be	AUX
ajlm-1946	93	3	an	an	DET
ajlm-1946	93	4	autosomal	autosomal	ADJ
ajlm-1946	93	5	recessive	recessive	ADJ
ajlm-1946	93	6	disorder	disorder	NOUN
ajlm-1946	93	7	that	that	PRON
ajlm-1946	93	8	is	be	AUX
ajlm-1946	93	9	caused	cause	VERB
ajlm-1946	93	10	by	by	ADP
ajlm-1946	93	11	a	a	DET
ajlm-1946	93	12	deficiency	deficiency	NOUN
ajlm-1946	93	13	of	of	ADP
ajlm-1946	93	14	the	the	DET
ajlm-1946	93	15	carbamoyl	carbamoyl	NOUN
ajlm-1946	93	16	phosphate	phosphate	ADJ
ajlm-1946	93	17	synthetase	synthetase	NOUN
ajlm-1946	93	18	1	1	NUM
ajlm-1946	93	19	enzyme	enzyme	NOUN
ajlm-1946	93	20	.	.	PUNCT
ajlm-1946	94	1	the	the	DET
ajlm-1946	94	2	main	main	ADJ
ajlm-1946	94	3	biochemical	biochemical	ADJ
ajlm-1946	94	4	characteristics	characteristic	NOUN
ajlm-1946	94	5	of	of	ADP
ajlm-1946	94	6	ucds	ucds	NOUN
ajlm-1946	94	7	are	be	AUX
ajlm-1946	94	8	extremely	extremely	ADV
ajlm-1946	94	9	high	high	ADJ
ajlm-1946	94	10	blood	blood	NOUN
ajlm-1946	94	11	ammonia	ammonia	NOUN
ajlm-1946	94	12	levels	level	NOUN
ajlm-1946	94	13	,	,	PUNCT
ajlm-1946	94	14	mr	mr	PROPN
ajlm-1946	94	15	,	,	PUNCT
ajlm-1946	94	16	and	and	CCONJ
ajlm-1946	94	17	a	a	DET
ajlm-1946	94	18	low	low	ADJ
ajlm-1946	94	19	urea	urea	NOUN
ajlm-1946	94	20	level	level	NOUN
ajlm-1946	94	21	.	.	PUNCT
ajlm-1946	95	1	because	because	SCONJ
ajlm-1946	95	2	of	of	ADP
ajlm-1946	95	3	the	the	DET
ajlm-1946	95	4	mr	mr	PROPN
ajlm-1946	95	5	that	that	PRON
ajlm-1946	95	6	comes	come	VERB
ajlm-1946	95	7	with	with	ADP
ajlm-1946	95	8	this	this	DET
ajlm-1946	95	9	metabolic	metabolic	NOUN
ajlm-1946	95	10	disorder	disorder	NOUN
ajlm-1946	95	11	,	,	PUNCT
ajlm-1946	95	12	early	early	ADJ
ajlm-1946	95	13	detection	detection	NOUN
ajlm-1946	95	14	is	be	AUX
ajlm-1946	95	15	critical	critical	ADJ
ajlm-1946	95	16	,	,	PUNCT
ajlm-1946	95	17	and	and	CCONJ
ajlm-1946	95	18	the	the	DET
ajlm-1946	95	19	diagnosis	diagnosis	NOUN
ajlm-1946	95	20	is	be	AUX
ajlm-1946	95	21	within	within	ADP
ajlm-1946	95	22	the	the	DET
ajlm-1946	95	23	capabilities	capability	NOUN
ajlm-1946	95	24	of	of	ADP
ajlm-1946	95	25	a	a	DET
ajlm-1946	95	26	typical	typical	ADJ
ajlm-1946	95	27	laboratory	laboratory	NOUN
ajlm-1946	95	28	.	.	PUNCT
ajlm-1946	96	1	to	to	PART
ajlm-1946	96	2	screen	screen	VERB
ajlm-1946	96	3	for	for	ADP
ajlm-1946	96	4	type	type	NOUN
ajlm-1946	96	5	1	1	NUM
ajlm-1946	96	6	hyperammonaemia	hyperammonaemia	NOUN
ajlm-1946	96	7	,	,	PUNCT
ajlm-1946	96	8	advanced	advanced	ADJ
ajlm-1946	96	9	methods	method	NOUN
ajlm-1946	96	10	such	such	ADJ
ajlm-1946	96	11	as	as	ADP
ajlm-1946	96	12	amino	amino	NOUN
ajlm-1946	96	13	acid	acid	NOUN
ajlm-1946	96	14	analysis	analysis	NOUN
ajlm-1946	96	15	using	use	VERB
ajlm-1946	96	16	high	high	ADJ
ajlm-1946	96	17	-	-	PUNCT
ajlm-1946	96	18	performance	performance	NOUN
ajlm-1946	96	19	liquid	liquid	ADJ
ajlm-1946	96	20	chromatography	chromatography	NOUN
ajlm-1946	96	21	or	or	CCONJ
ajlm-1946	96	22	tandem	tandem	PROPN
ajlm-1946	96	23	mass	mass	ADJ
ajlm-1946	96	24	spectrometry	spectrometry	NOUN
ajlm-1946	96	25	may	may	AUX
ajlm-1946	96	26	be	be	AUX
ajlm-1946	96	27	required	require	VERB
ajlm-1946	96	28	.	.	PUNCT
ajlm-1946	97	1	in	in	ADP
ajlm-1946	97	2	a	a	DET
ajlm-1946	97	3	resource	resource	NOUN
ajlm-1946	97	4	-	-	PUNCT
ajlm-1946	97	5	limited	limit	VERB
ajlm-1946	97	6	medical	medical	ADJ
ajlm-1946	97	7	facility	facility	NOUN
ajlm-1946	97	8	,	,	PUNCT
ajlm-1946	97	9	blood	blood	NOUN
ajlm-1946	97	10	gas	gas	NOUN
ajlm-1946	97	11	and	and	CCONJ
ajlm-1946	97	12	electrolyte	electrolyte	NOUN
ajlm-1946	97	13	abnormalities	abnormality	NOUN
ajlm-1946	97	14	are	be	AUX
ajlm-1946	97	15	important	important	ADJ
ajlm-1946	97	16	for	for	ADP
ajlm-1946	97	17	detecting	detect	VERB
ajlm-1946	97	18	ucds	ucds	PRON
ajlm-1946	97	19	.	.	PUNCT
ajlm-1946	98	1	the	the	DET
ajlm-1946	98	2	presence	presence	NOUN
ajlm-1946	98	3	of	of	ADP
ajlm-1946	98	4	reduced	reduce	VERB
ajlm-1946	98	5	blood	blood	NOUN
ajlm-1946	98	6	urea	urea	NOUN
ajlm-1946	98	7	levels	level	NOUN
ajlm-1946	98	8	,	,	PUNCT
ajlm-1946	98	9	increased	increase	VERB
ajlm-1946	98	10	ammonia	ammonia	NOUN
ajlm-1946	98	11	levels	level	NOUN
ajlm-1946	98	12	,	,	PUNCT
ajlm-1946	98	13	elevated	elevated	ADJ
ajlm-1946	98	14	transaminase	transaminase	NOUN
ajlm-1946	98	15	(	(	PUNCT
ajlm-1946	98	16	alanine	alanine	NOUN
ajlm-1946	98	17	transaminase	transaminase	NOUN
ajlm-1946	98	18	and	and	CCONJ
ajlm-1946	98	19	aspartate	aspartate	NOUN
ajlm-1946	98	20	transaminase	transaminase	NOUN
ajlm-1946	98	21	)	)	PUNCT
ajlm-1946	98	22	activity	activity	NOUN
ajlm-1946	98	23	,	,	PUNCT
ajlm-1946	98	24	and	and	CCONJ
ajlm-1946	98	25	coagulopathy	coagulopathy	ADJ
ajlm-1946	98	26	(	(	PUNCT
ajlm-1946	98	27	increased	increase	VERB
ajlm-1946	98	28	prothrombin	prothrombin	ADJ
ajlm-1946	98	29	time	time	NOUN
ajlm-1946	98	30	and	and	CCONJ
ajlm-1946	98	31	partial	partial	ADJ
ajlm-1946	98	32	thromboplastin	thromboplastin	NOUN
ajlm-1946	98	33	time	time	NOUN
ajlm-1946	98	34	)	)	PUNCT
ajlm-1946	98	35	should	should	AUX
ajlm-1946	98	36	be	be	AUX
ajlm-1946	98	37	strongly	strongly	ADV
ajlm-1946	98	38	suggestive	suggestive	ADJ
ajlm-1946	98	39	of	of	ADP
ajlm-1946	98	40	a	a	DET
ajlm-1946	98	41	urea	urea	NOUN
ajlm-1946	98	42	cycle	cycle	NOUN
ajlm-1946	98	43	defect	defect	NOUN
ajlm-1946	98	44	and	and	CCONJ
ajlm-1946	98	45	risk	risk	NOUN
ajlm-1946	98	46	of	of	ADP
ajlm-1946	98	47	encephalopathy	encephalopathy	NOUN
ajlm-1946	98	48	and	and	CCONJ
ajlm-1946	98	49	should	should	AUX
ajlm-1946	98	50	be	be	AUX
ajlm-1946	98	51	sufficient	sufficient	ADJ
ajlm-1946	98	52	basis	basis	NOUN
ajlm-1946	98	53	for	for	ADP
ajlm-1946	98	54	referring	refer	VERB
ajlm-1946	98	55	patients	patient	NOUN
ajlm-1946	98	56	for	for	ADP
ajlm-1946	98	57	specialist	specialist	ADJ
ajlm-1946	98	58	investigation	investigation	NOUN
ajlm-1946	98	59	and	and	CCONJ
ajlm-1946	98	60	initiating	initiate	VERB
ajlm-1946	98	61	early	early	ADJ
ajlm-1946	98	62	patient	patient	ADJ
ajlm-1946	98	63	management	management	NOUN
ajlm-1946	98	64	.	.	PUNCT
ajlm-1946	99	1	hyperammonaemia	hyperammonaemia	PROPN
ajlm-1946	99	2	type	type	PROPN
ajlm-1946	99	3	ii	ii	PROPN
ajlm-1946	99	4	the	the	DET
ajlm-1946	99	5	biochemical	biochemical	ADJ
ajlm-1946	99	6	lesion	lesion	NOUN
ajlm-1946	99	7	of	of	ADP
ajlm-1946	99	8	hyperammonaemia	hyperammonaemia	PROPN
ajlm-1946	99	9	type	type	PROPN
ajlm-1946	99	10	ii	ii	PROPN
ajlm-1946	99	11	is	be	AUX
ajlm-1946	99	12	a	a	DET
ajlm-1946	99	13	deficiency	deficiency	NOUN
ajlm-1946	99	14	of	of	ADP
ajlm-1946	99	15	the	the	DET
ajlm-1946	99	16	ornithine	ornithine	NOUN
ajlm-1946	99	17	transcarbamoyl	transcarbamoyl	ADJ
ajlm-1946	99	18	transferase	transferase	NOUN
ajlm-1946	99	19	enzyme	enzyme	NOUN
ajlm-1946	99	20	,	,	PUNCT
ajlm-1946	99	21	and	and	CCONJ
ajlm-1946	99	22	the	the	DET
ajlm-1946	99	23	inheritance	inheritance	NOUN
ajlm-1946	99	24	pattern	pattern	NOUN
ajlm-1946	99	25	is	be	AUX
ajlm-1946	99	26	x	x	NOUN
ajlm-1946	99	27	-	-	VERB
ajlm-1946	99	28	linked	link	VERB
ajlm-1946	99	29	.	.	PUNCT
ajlm-1946	100	1	the	the	DET
ajlm-1946	100	2	key	key	ADJ
ajlm-1946	100	3	features	feature	NOUN
ajlm-1946	100	4	of	of	ADP
ajlm-1946	100	5	this	this	DET
ajlm-1946	100	6	disorder	disorder	NOUN
ajlm-1946	100	7	include	include	VERB
ajlm-1946	100	8	elevated	elevated	ADJ
ajlm-1946	100	9	ammonia	ammonia	NOUN
ajlm-1946	100	10	levels	level	NOUN
ajlm-1946	100	11	in	in	ADP
ajlm-1946	100	12	the	the	DET
ajlm-1946	100	13	blood	blood	NOUN
ajlm-1946	100	14	,	,	PUNCT
ajlm-1946	100	15	cerebrospinal	cerebrospinal	ADJ
ajlm-1946	100	16	fluid	fluid	NOUN
ajlm-1946	100	17	and	and	CCONJ
ajlm-1946	100	18	urine	urine	NOUN
ajlm-1946	100	19	,	,	PUNCT
ajlm-1946	100	20	as	as	ADV
ajlm-1946	100	21	well	well	ADV
ajlm-1946	100	22	as	as	ADP
ajlm-1946	100	23	orotic	orotic	ADJ
ajlm-1946	100	24	aciduria	aciduria	NOUN
ajlm-1946	100	25	caused	cause	VERB
ajlm-1946	100	26	by	by	ADP
ajlm-1946	100	27	carbamoyl	carbamoyl	NOUN
ajlm-1946	100	28	phosphate	phosphate	NOUN
ajlm-1946	100	29	channelling	channelling	NOUN
ajlm-1946	100	30	into	into	ADP
ajlm-1946	100	31	pyrimidine	pyrimidine	NOUN
ajlm-1946	100	32	synthesis	synthesis	NOUN
ajlm-1946	100	33	.	.	PUNCT
ajlm-1946	101	1	hyperammonaemia	hyperammonaemia	PROPN
ajlm-1946	101	2	is	be	AUX
ajlm-1946	101	3	caused	cause	VERB
ajlm-1946	101	4	by	by	ADP
ajlm-1946	101	5	a	a	DET
ajlm-1946	101	6	lack	lack	NOUN
ajlm-1946	101	7	of	of	ADP
ajlm-1946	101	8	any	any	PRON
ajlm-1946	101	9	of	of	ADP
ajlm-1946	101	10	the	the	DET
ajlm-1946	101	11	urea	urea	NOUN
ajlm-1946	101	12	cycle	cycle	NOUN
ajlm-1946	101	13	enzymes	enzyme	NOUN
ajlm-1946	101	14	.	.	PUNCT
ajlm-1946	102	1	if	if	SCONJ
ajlm-1946	102	2	the	the	DET
ajlm-1946	102	3	metabolic	metabolic	NOUN
ajlm-1946	102	4	block	block	NOUN
ajlm-1946	102	5	occurs	occur	VERB
ajlm-1946	102	6	in	in	ADP
ajlm-1946	102	7	one	one	NUM
ajlm-1946	102	8	of	of	ADP
ajlm-1946	102	9	the	the	DET
ajlm-1946	102	10	earlier	early	ADJ
ajlm-1946	102	11	steps	step	NOUN
ajlm-1946	102	12	of	of	ADP
ajlm-1946	102	13	the	the	DET
ajlm-1946	102	14	urea	urea	NOUN
ajlm-1946	102	15	cycle	cycle	NOUN
ajlm-1946	102	16	,	,	PUNCT
ajlm-1946	102	17	ammonia	ammonia	NOUN
ajlm-1946	102	18	,	,	PUNCT
ajlm-1946	102	19	which	which	PRON
ajlm-1946	102	20	is	be	AUX
ajlm-1946	102	21	neurotoxic	neurotoxic	ADJ
ajlm-1946	102	22	,	,	PUNCT
ajlm-1946	102	23	accumulates	accumulate	VERB
ajlm-1946	102	24	and	and	CCONJ
ajlm-1946	102	25	causes	cause	VERB
ajlm-1946	102	26	a	a	DET
ajlm-1946	102	27	more	more	ADV
ajlm-1946	102	28	severe	severe	ADJ
ajlm-1946	102	29	condition	condition	NOUN
ajlm-1946	102	30	.	.	PUNCT
ajlm-1946	103	1	conversely	conversely	ADV
ajlm-1946	103	2	,	,	PUNCT
ajlm-1946	103	3	the	the	DET
ajlm-1946	103	4	absence	absence	NOUN
ajlm-1946	103	5	of	of	ADP
ajlm-1946	103	6	enzymes	enzyme	NOUN
ajlm-1946	103	7	catalysing	catalyse	VERB
ajlm-1946	103	8	reactions	reaction	NOUN
ajlm-1946	103	9	in	in	ADP
ajlm-1946	103	10	the	the	DET
ajlm-1946	103	11	later	later	ADJ
ajlm-1946	103	12	stages	stage	NOUN
ajlm-1946	103	13	of	of	ADP
ajlm-1946	103	14	the	the	DET
ajlm-1946	103	15	urea	urea	NOUN
ajlm-1946	103	16	cycle	cycle	NOUN
ajlm-1946	103	17	results	result	NOUN
ajlm-1946	103	18	in	in	ADP
ajlm-1946	103	19	the	the	DET
ajlm-1946	103	20	accumulation	accumulation	NOUN
ajlm-1946	103	21	of	of	ADP
ajlm-1946	103	22	less	less	ADV
ajlm-1946	103	23	toxic	toxic	ADJ
ajlm-1946	103	24	intermediates	intermediate	NOUN
ajlm-1946	103	25	and	and	CCONJ
ajlm-1946	103	26	less	less	ADV
ajlm-1946	103	27	severe	severe	ADJ
ajlm-1946	103	28	symptoms	symptom	NOUN
ajlm-1946	103	29	.	.	PUNCT
ajlm-1946	104	1	hence	hence	ADV
ajlm-1946	104	2	,	,	PUNCT
ajlm-1946	104	3	the	the	DET
ajlm-1946	104	4	exact	exact	ADJ
ajlm-1946	104	5	point	point	NOUN
ajlm-1946	104	6	of	of	ADP
ajlm-1946	104	7	the	the	DET
ajlm-1946	104	8	metabolic	metabolic	NOUN
ajlm-1946	104	9	block	block	NOUN
ajlm-1946	104	10	needs	need	VERB
ajlm-1946	104	11	to	to	PART
ajlm-1946	104	12	be	be	AUX
ajlm-1946	104	13	identified	identify	VERB
ajlm-1946	104	14	as	as	SCONJ
ajlm-1946	104	15	it	it	PRON
ajlm-1946	104	16	determines	determine	VERB
ajlm-1946	104	17	the	the	DET
ajlm-1946	104	18	prognosis	prognosis	NOUN
ajlm-1946	104	19	.	.	PUNCT
ajlm-1946	105	1	because	because	SCONJ
ajlm-1946	105	2	the	the	DET
ajlm-1946	105	3	brain	brain	NOUN
ajlm-1946	105	4	is	be	AUX
ajlm-1946	105	5	sensitive	sensitive	ADJ
ajlm-1946	105	6	to	to	ADP
ajlm-1946	105	7	ammonia	ammonia	NOUN
ajlm-1946	105	8	,	,	PUNCT
ajlm-1946	105	9	hyperammonaemia	hyperammonaemia	NOUN
ajlm-1946	105	10	,	,	PUNCT
ajlm-1946	105	11	as	as	ADV
ajlm-1946	105	12	well	well	ADV
ajlm-1946	105	13	as	as	ADP
ajlm-1946	105	14	elevated	elevated	ADJ
ajlm-1946	105	15	ammonia	ammonia	NOUN
ajlm-1946	105	16	levels	level	NOUN
ajlm-1946	105	17	in	in	ADP
ajlm-1946	105	18	other	other	ADJ
ajlm-1946	105	19	body	body	NOUN
ajlm-1946	105	20	fluids	fluid	NOUN
ajlm-1946	105	21	,	,	PUNCT
ajlm-1946	105	22	causes	cause	VERB
ajlm-1946	105	23	toxic	toxic	ADJ
ajlm-1946	105	24	symptoms	symptom	NOUN
ajlm-1946	105	25	and	and	CCONJ
ajlm-1946	105	26	neurological	neurological	ADJ
ajlm-1946	105	27	damage	damage	NOUN
ajlm-1946	105	28	.	.	PUNCT
ajlm-1946	106	1	understanding	understand	VERB
ajlm-1946	106	2	the	the	DET
ajlm-1946	106	3	situation	situation	NOUN
ajlm-1946	106	4	is	be	AUX
ajlm-1946	106	5	critical	critical	ADJ
ajlm-1946	106	6	because	because	SCONJ
ajlm-1946	106	7	it	it	PRON
ajlm-1946	106	8	guides	guide	VERB
ajlm-1946	106	9	treatment	treatment	NOUN
ajlm-1946	106	10	,	,	PUNCT
ajlm-1946	106	11	which	which	PRON
ajlm-1946	106	12	primarily	primarily	ADV
ajlm-1946	106	13	consists	consist	VERB
ajlm-1946	106	14	of	of	ADP
ajlm-1946	106	15	a	a	DET
ajlm-1946	106	16	low	low	ADJ
ajlm-1946	106	17	-	-	PUNCT
ajlm-1946	106	18	protein	protein	NOUN
ajlm-1946	106	19	diet	diet	NOUN
ajlm-1946	106	20	and	and	CCONJ
ajlm-1946	106	21	frequent	frequent	ADJ
ajlm-1946	106	22	small	small	ADJ
ajlm-1946	106	23	feeds	feed	NOUN
ajlm-1946	106	24	.	.	PUNCT
ajlm-1946	107	1	hippuric	hippuric	ADJ
ajlm-1946	107	2	acid	acid	NOUN
ajlm-1946	107	3	formation	formation	NOUN
ajlm-1946	107	4	(	(	PUNCT
ajlm-1946	107	5	conjugation	conjugation	NOUN
ajlm-1946	107	6	product	product	NOUN
ajlm-1946	107	7	between	between	ADP
ajlm-1946	107	8	glycine	glycine	NOUN
ajlm-1946	107	9	and	and	CCONJ
ajlm-1946	107	10	benzoyl	benzoyl	NOUN
ajlm-1946	107	11	is	be	AUX
ajlm-1946	107	12	a	a	DET
ajlm-1946	107	13	detoxification	detoxification	NOUN
ajlm-1946	107	14	step	step	NOUN
ajlm-1946	107	15	)	)	PUNCT
ajlm-1946	107	16	or	or	CCONJ
ajlm-1946	107	17	phenylacetyl	phenylacetyl	NOUN
ajlm-1946	107	18	glycine	glycine	NOUN
ajlm-1946	107	19	can	can	AUX
ajlm-1946	107	20	also	also	ADV
ajlm-1946	107	21	eliminate	eliminate	VERB
ajlm-1946	107	22	amino	amino	NOUN
ajlm-1946	107	23	nitrogen	nitrogen	NOUN
ajlm-1946	107	24	.	.	PUNCT
ajlm-1946	108	1	citrullinaemia	citrullinaemia	PROPN
ajlm-1946	108	2	citrullinaemia	citrullinaemia	PROPN
ajlm-1946	108	3	is	be	AUX
ajlm-1946	108	4	another	another	DET
ajlm-1946	108	5	example	example	NOUN
ajlm-1946	108	6	of	of	ADP
ajlm-1946	108	7	ucds	ucds	PROPN
ajlm-1946	108	8	.	.	PUNCT
ajlm-1946	109	1	citrullinaemia	citrullinaemia	PROPN
ajlm-1946	109	2	is	be	AUX
ajlm-1946	109	3	caused	cause	VERB
ajlm-1946	109	4	by	by	ADP
ajlm-1946	109	5	arginosuccinate	arginosuccinate	ADJ
ajlm-1946	109	6	synthetase	synthetase	NOUN
ajlm-1946	109	7	deficiency	deficiency	NOUN
ajlm-1946	109	8	,	,	PUNCT
ajlm-1946	109	9	which	which	PRON
ajlm-1946	109	10	results	result	VERB
ajlm-1946	109	11	in	in	ADP
ajlm-1946	109	12	elevated	elevated	ADJ
ajlm-1946	109	13	ammonia	ammonia	NOUN
ajlm-1946	109	14	and	and	CCONJ
ajlm-1946	109	15	citrulline	citrulline	NOUN
ajlm-1946	109	16	levels	level	NOUN
ajlm-1946	109	17	in	in	ADP
ajlm-1946	109	18	the	the	DET
ajlm-1946	109	19	blood	blood	NOUN
ajlm-1946	109	20	.	.	PUNCT
ajlm-1946	110	1	breast	breast	NOUN
ajlm-1946	110	2	milk	milk	NOUN
ajlm-1946	110	3	should	should	AUX
ajlm-1946	110	4	be	be	AUX
ajlm-1946	110	5	avoided	avoid	VERB
ajlm-1946	110	6	in	in	ADP
ajlm-1946	110	7	this	this	DET
ajlm-1946	110	8	condition	condition	NOUN
ajlm-1946	110	9	because	because	SCONJ
ajlm-1946	110	10	it	it	PRON
ajlm-1946	110	11	contains	contain	VERB
ajlm-1946	110	12	high	high	ADJ
ajlm-1946	110	13	amounts	amount	NOUN
ajlm-1946	110	14	of	of	ADP
ajlm-1946	110	15	citrulline	citrulline	NOUN
ajlm-1946	110	16	.	.	PUNCT
ajlm-1946	111	1	hyperornithinaemia	hyperornithinaemia	VERB
ajlm-1946	111	2	another	another	DET
ajlm-1946	111	3	urea	urea	NOUN
ajlm-1946	111	4	cycle	cycle	NOUN
ajlm-1946	111	5	enzyme	enzyme	NOUN
ajlm-1946	111	6	deficiency	deficiency	NOUN
ajlm-1946	111	7	is	be	AUX
ajlm-1946	111	8	hyperornithinaemia	hyperornithinaemia	PROPN
ajlm-1946	111	9	,	,	PUNCT
ajlm-1946	111	10	which	which	PRON
ajlm-1946	111	11	is	be	AUX
ajlm-1946	111	12	an	an	DET
ajlm-1946	111	13	ornithine	ornithine	ADJ
ajlm-1946	111	14	transport	transport	NOUN
ajlm-1946	111	15	defect	defect	NOUN
ajlm-1946	111	16	.	.	PUNCT
ajlm-1946	112	1	it	it	PRON
ajlm-1946	112	2	is	be	AUX
ajlm-1946	112	3	an	an	DET
ajlm-1946	112	4	autosomal	autosomal	ADJ
ajlm-1946	112	5	recessive	recessive	ADJ
ajlm-1946	112	6	condition	condition	NOUN
ajlm-1946	112	7	in	in	ADP
ajlm-1946	112	8	which	which	PRON
ajlm-1946	112	9	ammonia	ammonia	NOUN
ajlm-1946	112	10	and	and	CCONJ
ajlm-1946	112	11	ornithine	ornithine	NOUN
ajlm-1946	112	12	levels	level	NOUN
ajlm-1946	112	13	in	in	ADP
ajlm-1946	112	14	the	the	DET
ajlm-1946	112	15	blood	blood	NOUN
ajlm-1946	112	16	are	be	AUX
ajlm-1946	112	17	elevated	elevate	VERB
ajlm-1946	112	18	.	.	PUNCT
ajlm-1946	113	1	hyperargininaemia	hyperargininaemia	NOUN
ajlm-1946	113	2	hyperargininaemia	hyperargininaemia	NOUN
ajlm-1946	113	3	,	,	PUNCT
ajlm-1946	113	4	which	which	PRON
ajlm-1946	113	5	results	result	VERB
ajlm-1946	113	6	from	from	ADP
ajlm-1946	113	7	arginase	arginase	ADJ
ajlm-1946	113	8	deficiency	deficiency	NOUN
ajlm-1946	113	9	and	and	CCONJ
ajlm-1946	113	10	causes	cause	VERB
ajlm-1946	113	11	arginine	arginine	NOUN
ajlm-1946	113	12	accumulation	accumulation	NOUN
ajlm-1946	113	13	in	in	ADP
ajlm-1946	113	14	the	the	DET
ajlm-1946	113	15	blood	blood	NOUN
ajlm-1946	113	16	and	and	CCONJ
ajlm-1946	113	17	cerebrospinal	cerebrospinal	ADJ
ajlm-1946	113	18	fluid	fluid	NOUN
ajlm-1946	113	19	,	,	PUNCT
ajlm-1946	113	20	is	be	AUX
ajlm-1946	113	21	another	another	DET
ajlm-1946	113	22	metabolic	metabolic	NOUN
ajlm-1946	113	23	abnormality	abnormality	NOUN
ajlm-1946	113	24	seen	see	VERB
ajlm-1946	113	25	in	in	ADP
ajlm-1946	113	26	ucds	ucds	PRON
ajlm-1946	113	27	.	.	PUNCT
ajlm-1946	114	1	it	it	PRON
ajlm-1946	114	2	is	be	AUX
ajlm-1946	114	3	worth	worth	ADJ
ajlm-1946	114	4	noting	note	VERB
ajlm-1946	114	5	that	that	SCONJ
ajlm-1946	114	6	in	in	ADP
ajlm-1946	114	7	this	this	DET
ajlm-1946	114	8	condition	condition	NOUN
ajlm-1946	114	9	,	,	PUNCT
ajlm-1946	114	10	cysteine	cysteine	NOUN
ajlm-1946	114	11	and	and	CCONJ
ajlm-1946	114	12	lysine	lysine	NOUN
ajlm-1946	114	13	are	be	AUX
ajlm-1946	114	14	excreted	excrete	VERB
ajlm-1946	114	15	in	in	ADP
ajlm-1946	114	16	the	the	DET
ajlm-1946	114	17	urine	urine	NOUN
ajlm-1946	114	18	instead	instead	ADV
ajlm-1946	114	19	of	of	ADP
ajlm-1946	114	20	arginine	arginine	NOUN
ajlm-1946	114	21	.	.	PUNCT
ajlm-1946	115	1	mass	mass	ADJ
ajlm-1946	115	2	spectrometry	spectrometry	NOUN
ajlm-1946	115	3	can	can	AUX
ajlm-1946	115	4	be	be	AUX
ajlm-1946	115	5	used	use	VERB
ajlm-1946	115	6	to	to	PART
ajlm-1946	115	7	screen	screen	VERB
ajlm-1946	115	8	for	for	ADP
ajlm-1946	115	9	hyperargininaemia	hyperargininaemia	NOUN
ajlm-1946	115	10	.	.	PUNCT
ajlm-1946	116	1	purine	purine	NOUN
ajlm-1946	116	2	metabolism	metabolism	NOUN
ajlm-1946	116	3	disorder	disorder	NOUN
ajlm-1946	116	4	purine	purine	NOUN
ajlm-1946	116	5	metabolism	metabolism	NOUN
ajlm-1946	116	6	disorder	disorder	NOUN
ajlm-1946	116	7	is	be	AUX
ajlm-1946	116	8	best	well	ADV
ajlm-1946	116	9	illustrated	illustrate	VERB
ajlm-1946	116	10	by	by	ADP
ajlm-1946	116	11	lesch	lesch	PROPN
ajlm-1946	116	12	-	-	PUNCT
ajlm-1946	116	13	nyhan	nyhan	NOUN
ajlm-1946	116	14	’s	’s	PART
ajlm-1946	116	15	(	(	PUNCT
ajlm-1946	116	16	l	l	NOUN
ajlm-1946	116	17	-	-	PUNCT
ajlm-1946	116	18	n	n	CCONJ
ajlm-1946	116	19	)	)	PUNCT
ajlm-1946	116	20	syndrome	syndrome	NOUN
ajlm-1946	116	21	,	,	PUNCT
ajlm-1946	116	22	an	an	DET
ajlm-1946	116	23	x	x	ADV
ajlm-1946	116	24	-	-	ADJ
ajlm-1946	116	25	linked	link	VERB
ajlm-1946	116	26	inherited	inherit	VERB
ajlm-1946	116	27	purine	purine	NOUN
ajlm-1946	116	28	metabolism	metabolism	NOUN
ajlm-1946	116	29	disorder	disorder	NOUN
ajlm-1946	116	30	.	.	PUNCT
ajlm-1946	117	1	the	the	DET
ajlm-1946	117	2	biochemical	biochemical	ADJ
ajlm-1946	117	3	lesion	lesion	NOUN
ajlm-1946	117	4	is	be	AUX
ajlm-1946	117	5	caused	cause	VERB
ajlm-1946	117	6	by	by	ADP
ajlm-1946	117	7	a	a	DET
ajlm-1946	117	8	hypoxanthine	hypoxanthine	NOUN
ajlm-1946	117	9	-	-	PUNCT
ajlm-1946	117	10	guanine	guanine	NOUN
ajlm-1946	117	11	phosphoribosyltransferase	phosphoribosyltransferase	NOUN
ajlm-1946	117	12	deficiency	deficiency	NOUN
ajlm-1946	117	13	,	,	PUNCT
ajlm-1946	117	14	which	which	PRON
ajlm-1946	117	15	impairs	impair	VERB
ajlm-1946	117	16	the	the	DET
ajlm-1946	117	17	purine	purine	NOUN
ajlm-1946	117	18	salvage	salvage	NOUN
ajlm-1946	117	19	pathway	pathway	NOUN
ajlm-1946	117	20	.	.	PUNCT
ajlm-1946	118	1	this	this	DET
ajlm-1946	118	2	results	result	NOUN
ajlm-1946	118	3	in	in	ADP
ajlm-1946	118	4	the	the	DET
ajlm-1946	118	5	accumulation	accumulation	NOUN
ajlm-1946	118	6	of	of	ADP
ajlm-1946	118	7	phosphoribosyl	phosphoribosyl	ADJ
ajlm-1946	118	8	pyrophosphate	pyrophosphate	NOUN
ajlm-1946	118	9	,	,	PUNCT
ajlm-1946	118	10	an	an	DET
ajlm-1946	118	11	intermediate	intermediate	ADJ
ajlm-1946	118	12	in	in	ADP
ajlm-1946	118	13	the	the	DET
ajlm-1946	118	14	purine	purine	NOUN
ajlm-1946	118	15	synthetic	synthetic	ADJ
ajlm-1946	118	16	pathway	pathway	NOUN
ajlm-1946	118	17	,	,	PUNCT
ajlm-1946	118	18	and	and	CCONJ
ajlm-1946	118	19	other	other	ADJ
ajlm-1946	118	20	purine	purine	NOUN
ajlm-1946	118	21	synthetic	synthetic	NOUN
ajlm-1946	118	22	cycle	cycle	NOUN
ajlm-1946	118	23	intermediates	intermediate	NOUN
ajlm-1946	118	24	in	in	ADP
ajlm-1946	118	25	the	the	DET
ajlm-1946	118	26	biosynthetic	biosynthetic	ADJ
ajlm-1946	118	27	pathway	pathway	NOUN
ajlm-1946	118	28	.	.	PUNCT
ajlm-1946	119	1	hypoxanthine	hypoxanthine	NOUN
ajlm-1946	119	2	-	-	PUNCT
ajlm-1946	119	3	guanine	guanine	NOUN
ajlm-1946	119	4	phosphoribosyltransferase	phosphoribosyltransferase	NOUN
ajlm-1946	119	5	activity	activity	NOUN
ajlm-1946	119	6	is	be	AUX
ajlm-1946	119	7	normal	normal	ADJ
ajlm-1946	119	8	in	in	ADP
ajlm-1946	119	9	the	the	DET
ajlm-1946	119	10	brain	brain	NOUN
ajlm-1946	119	11	and	and	CCONJ
ajlm-1946	119	12	at	at	ADP
ajlm-1946	119	13	low	low	ADJ
ajlm-1946	119	14	levels	level	NOUN
ajlm-1946	119	15	in	in	ADP
ajlm-1946	119	16	the	the	DET
ajlm-1946	119	17	liver	liver	NOUN
ajlm-1946	119	18	and	and	CCONJ
ajlm-1946	119	19	spleen.23	spleen.23	VERB
ajlm-1946	119	20	some	some	PRON
ajlm-1946	119	21	of	of	ADP
ajlm-1946	119	22	the	the	DET
ajlm-1946	119	23	neurological	neurological	ADJ
ajlm-1946	119	24	manifestations	manifestation	NOUN
ajlm-1946	119	25	of	of	ADP
ajlm-1946	119	26	l	l	NOUN
ajlm-1946	119	27	-	-	PUNCT
ajlm-1946	119	28	n	n	PRON
ajlm-1946	119	29	syndrome	syndrome	NOUN
ajlm-1946	119	30	are	be	AUX
ajlm-1946	119	31	thought	think	VERB
ajlm-1946	119	32	to	to	PART
ajlm-1946	119	33	be	be	AUX
ajlm-1946	119	34	due	due	ADJ
ajlm-1946	119	35	to	to	ADP
ajlm-1946	119	36	the	the	DET
ajlm-1946	119	37	toxicity	toxicity	NOUN
ajlm-1946	119	38	of	of	ADP
ajlm-1946	119	39	the	the	DET
ajlm-1946	119	40	purine	purine	NOUN
ajlm-1946	119	41	degradation	degradation	NOUN
ajlm-1946	119	42	products	product	NOUN
ajlm-1946	119	43	to	to	ADP
ajlm-1946	119	44	the	the	DET
ajlm-1946	119	45	developing	develop	VERB
ajlm-1946	119	46	central	central	ADJ
ajlm-1946	119	47	nervous	nervous	ADJ
ajlm-1946	119	48	system	system	NOUN
ajlm-1946	119	49	or	or	CCONJ
ajlm-1946	119	50	the	the	DET
ajlm-1946	119	51	absence	absence	NOUN
ajlm-1946	119	52	of	of	ADP
ajlm-1946	119	53	hypoxanthine	hypoxanthine	NOUN
ajlm-1946	119	54	-	-	PUNCT
ajlm-1946	119	55	guanine	guanine	NOUN
ajlm-1946	119	56	phosphoribosyltransferase	phosphoribosyltransferase	NOUN
ajlm-1946	119	57	,	,	PUNCT
ajlm-1946	119	58	which	which	PRON
ajlm-1946	119	59	results	result	VERB
ajlm-1946	119	60	in	in	ADP
ajlm-1946	119	61	an	an	DET
ajlm-1946	119	62	imbalance	imbalance	NOUN
ajlm-1946	119	63	in	in	ADP
ajlm-1946	119	64	adenine	adenine	NOUN
ajlm-1946	119	65	and	and	CCONJ
ajlm-1946	119	66	guanine	guanine	NOUN
ajlm-1946	119	67	nucleotides	nucleotide	NOUN
ajlm-1946	119	68	at	at	ADP
ajlm-1946	119	69	a	a	DET
ajlm-1946	119	70	critical	critical	ADJ
ajlm-1946	119	71	developmental	developmental	ADJ
ajlm-1946	119	72	phase	phase	NOUN
ajlm-1946	119	73	for	for	ADP
ajlm-1946	119	74	the	the	DET
ajlm-1946	119	75	infant.24	infant.24	ADJ
ajlm-1946	119	76	self	self	NOUN
ajlm-1946	119	77	-	-	PUNCT
ajlm-1946	119	78	mutilation	mutilation	NOUN
ajlm-1946	119	79	,	,	PUNCT
ajlm-1946	119	80	mr	mr	PROPN
ajlm-1946	119	81	,	,	PUNCT
ajlm-1946	119	82	raised	raise	VERB
ajlm-1946	119	83	uric	uric	ADJ
ajlm-1946	119	84	acid	acid	NOUN
ajlm-1946	119	85	levels	level	NOUN
ajlm-1946	119	86	(	(	PUNCT
ajlm-1946	119	87	described	describe	VERB
ajlm-1946	119	88	as	as	ADP
ajlm-1946	119	89	petit	petit	NOUN
ajlm-1946	119	90	gout	gout	NOUN
ajlm-1946	119	91	)	)	PUNCT
ajlm-1946	119	92	,	,	PUNCT
ajlm-1946	119	93	nephrolithiasis	nephrolithiasis	NOUN
ajlm-1946	119	94	(	(	PUNCT
ajlm-1946	119	95	renal	renal	ADJ
ajlm-1946	119	96	stone	stone	NOUN
ajlm-1946	119	97	)	)	PUNCT
ajlm-1946	119	98	,	,	PUNCT
ajlm-1946	119	99	and	and	CCONJ
ajlm-1946	119	100	gout	gout	NOUN
ajlm-1946	119	101	later	later	ADV
ajlm-1946	119	102	in	in	ADP
ajlm-1946	119	103	life	life	NOUN
ajlm-1946	119	104	are	be	AUX
ajlm-1946	119	105	the	the	DET
ajlm-1946	119	106	main	main	ADJ
ajlm-1946	119	107	characteristics	characteristic	NOUN
ajlm-1946	119	108	of	of	ADP
ajlm-1946	119	109	l	l	NOUN
ajlm-1946	119	110	-	-	ADJ
ajlm-1946	119	111	n	n	PRON
ajlm-1946	119	112	syndrome	syndrome	NOUN
ajlm-1946	119	113	.	.	PUNCT
ajlm-1946	120	1	the	the	DET
ajlm-1946	120	2	elevated	elevated	ADJ
ajlm-1946	120	3	uric	uric	ADJ
ajlm-1946	120	4	acid	acid	NOUN
ajlm-1946	120	5	level	level	NOUN
ajlm-1946	120	6	in	in	ADP
ajlm-1946	120	7	relation	relation	NOUN
ajlm-1946	120	8	to	to	ADP
ajlm-1946	120	9	the	the	DET
ajlm-1946	120	10	patient	patient	NOUN
ajlm-1946	120	11	’s	’s	PART
ajlm-1946	120	12	age	age	NOUN
ajlm-1946	120	13	and	and	CCONJ
ajlm-1946	120	14	other	other	ADJ
ajlm-1946	120	15	clinical	clinical	ADJ
ajlm-1946	120	16	manifestations	manifestation	NOUN
ajlm-1946	120	17	,	,	PUNCT
ajlm-1946	120	18	such	such	ADJ
ajlm-1946	120	19	as	as	ADP
ajlm-1946	120	20	mr	mr	PROPN
ajlm-1946	120	21	,	,	PUNCT
ajlm-1946	120	22	are	be	AUX
ajlm-1946	120	23	sufficient	sufficient	ADJ
ajlm-1946	120	24	indications	indication	NOUN
ajlm-1946	120	25	for	for	ADP
ajlm-1946	120	26	l	l	NOUN
ajlm-1946	120	27	-	-	PUNCT
ajlm-1946	120	28	n	n	PRON
ajlm-1946	120	29	syndrome	syndrome	NOUN
ajlm-1946	120	30	diagnosis	diagnosis	NOUN
ajlm-1946	120	31	in	in	ADP
ajlm-1946	120	32	resource	resource	NOUN
ajlm-1946	120	33	-	-	PUNCT
ajlm-1946	120	34	limited	limit	VERB
ajlm-1946	120	35	countries	country	NOUN
ajlm-1946	120	36	.	.	PUNCT
ajlm-1946	121	1	molecular	molecular	ADJ
ajlm-1946	121	2	investigation	investigation	NOUN
ajlm-1946	121	3	for	for	ADP
ajlm-1946	121	4	confirmation	confirmation	NOUN
ajlm-1946	121	5	may	may	AUX
ajlm-1946	121	6	be	be	AUX
ajlm-1946	121	7	requested	request	VERB
ajlm-1946	121	8	from	from	ADP
ajlm-1946	121	9	referral	referral	ADJ
ajlm-1946	121	10	centres	centre	NOUN
ajlm-1946	121	11	.	.	PUNCT
ajlm-1946	122	1	tangier	tangy	ADJ
ajlm-1946	122	2	’s	’s	PART
ajlm-1946	122	3	disease	disease	NOUN
ajlm-1946	122	4	tangier	tangy	ADJ
ajlm-1946	122	5	’s	’s	PART
ajlm-1946	122	6	disease	disease	NOUN
ajlm-1946	122	7	is	be	AUX
ajlm-1946	122	8	one	one	NUM
ajlm-1946	122	9	of	of	ADP
ajlm-1946	122	10	the	the	DET
ajlm-1946	122	11	common	common	ADJ
ajlm-1946	122	12	iems	iem	NOUN
ajlm-1946	122	13	of	of	ADP
ajlm-1946	122	14	lipid	lipid	ADJ
ajlm-1946	122	15	metabolism	metabolism	NOUN
ajlm-1946	122	16	.	.	PUNCT
ajlm-1946	123	1	tangier	tangy	ADJ
ajlm-1946	123	2	’s	’s	PART
ajlm-1946	123	3	disease	disease	NOUN
ajlm-1946	123	4	is	be	AUX
ajlm-1946	123	5	an	an	DET
ajlm-1946	123	6	autosomal	autosomal	ADJ
ajlm-1946	123	7	dominant	dominant	ADJ
ajlm-1946	123	8	metabolic	metabolic	NOUN
ajlm-1946	123	9	disorder	disorder	NOUN
ajlm-1946	123	10	that	that	PRON
ajlm-1946	123	11	derives	derive	VERB
ajlm-1946	123	12	from	from	ADP
ajlm-1946	123	13	the	the	DET
ajlm-1946	123	14	deficiency	deficiency	NOUN
ajlm-1946	123	15	of	of	ADP
ajlm-1946	123	16	adenosine	adenosine	ADJ
ajlm-1946	123	17	triphosphate	triphosphate	NOUN
ajlm-1946	123	18	-	-	PUNCT
ajlm-1946	123	19	binding	bind	VERB
ajlm-1946	123	20	cassette	cassette	NOUN
ajlm-1946	123	21	transporter-1	transporter-1	PROPN
ajlm-1946	123	22	.	.	PUNCT
ajlm-1946	124	1	the	the	DET
ajlm-1946	124	2	key	key	ADJ
ajlm-1946	124	3	biochemical	biochemical	ADJ
ajlm-1946	124	4	and	and	CCONJ
ajlm-1946	124	5	clinical	clinical	ADJ
ajlm-1946	124	6	characteristics	characteristic	NOUN
ajlm-1946	124	7	of	of	ADP
ajlm-1946	124	8	tangier	tangy	ADJ
ajlm-1946	124	9	’s	’s	PART
ajlm-1946	124	10	disease	disease	NOUN
ajlm-1946	124	11	include	include	VERB
ajlm-1946	124	12	defective	defective	ADJ
ajlm-1946	124	13	efflux	efflux	NOUN
ajlm-1946	124	14	of	of	ADP
ajlm-1946	124	15	cholesterol	cholesterol	NOUN
ajlm-1946	124	16	from	from	ADP
ajlm-1946	124	17	cells	cell	NOUN
ajlm-1946	124	18	,	,	PUNCT
ajlm-1946	124	19	reduction	reduction	NOUN
ajlm-1946	124	20	in	in	ADP
ajlm-1946	124	21	high	high	ADJ
ajlm-1946	124	22	-	-	PUNCT
ajlm-1946	124	23	density	density	NOUN
ajlm-1946	124	24	lipoprotein	lipoprotein	ADJ
ajlm-1946	124	25	levels	level	NOUN
ajlm-1946	124	26	in	in	ADP
ajlm-1946	124	27	the	the	DET
ajlm-1946	124	28	blood	blood	NOUN
ajlm-1946	124	29	,	,	PUNCT
ajlm-1946	124	30	absence	absence	NOUN
ajlm-1946	124	31	of	of	ADP
ajlm-1946	124	32	the	the	DET
ajlm-1946	124	33	α	α	NOUN
ajlm-1946	124	34	-	-	NOUN
ajlm-1946	124	35	band	band	NOUN
ajlm-1946	124	36	in	in	ADP
ajlm-1946	124	37	serum	serum	NOUN
ajlm-1946	124	38	protein	protein	NOUN
ajlm-1946	124	39	electrophoresis	electrophoresis	NOUN
ajlm-1946	124	40	,	,	PUNCT
ajlm-1946	124	41	accumulation	accumulation	NOUN
ajlm-1946	124	42	of	of	ADP
ajlm-1946	124	43	cholesterol	cholesterol	NOUN
ajlm-1946	124	44	esters	ester	NOUN
ajlm-1946	124	45	in	in	ADP
ajlm-1946	124	46	tissues	tissue	NOUN
ajlm-1946	124	47	,	,	PUNCT
ajlm-1946	124	48	presence	presence	NOUN
ajlm-1946	124	49	of	of	ADP
ajlm-1946	124	50	large	large	ADJ
ajlm-1946	124	51	orange	orange	ADJ
ajlm-1946	124	52	-	-	PUNCT
ajlm-1946	124	53	yellow	yellow	NOUN
ajlm-1946	124	54	tonsils	tonsil	NOUN
ajlm-1946	124	55	,	,	PUNCT
ajlm-1946	124	56	and	and	CCONJ
ajlm-1946	124	57	muscle	muscle	NOUN
ajlm-1946	124	58	atrophy	atrophy	NOUN
ajlm-1946	124	59	associated	associate	VERB
ajlm-1946	124	60	with	with	ADP
ajlm-1946	124	61	recurrent	recurrent	ADJ
ajlm-1946	124	62	neuropathies	neuropathy	NOUN
ajlm-1946	124	63	and	and	CCONJ
ajlm-1946	124	64	atherosclerosis	atherosclerosis	NOUN
ajlm-1946	124	65	.	.	PUNCT
ajlm-1946	125	1	the	the	DET
ajlm-1946	125	2	aforementioned	aforementioned	ADJ
ajlm-1946	125	3	features	feature	NOUN
ajlm-1946	125	4	of	of	ADP
ajlm-1946	125	5	the	the	DET
ajlm-1946	125	6	disease	disease	NOUN
ajlm-1946	125	7	are	be	AUX
ajlm-1946	125	8	sufficient	sufficient	ADJ
ajlm-1946	125	9	indicators	indicator	NOUN
ajlm-1946	125	10	for	for	ADP
ajlm-1946	125	11	the	the	DET
ajlm-1946	125	12	early	early	ADJ
ajlm-1946	125	13	detection	detection	NOUN
ajlm-1946	125	14	of	of	ADP
ajlm-1946	125	15	tangier	tangy	ADJ
ajlm-1946	125	16	’s	’s	PART
ajlm-1946	125	17	disease	disease	NOUN
ajlm-1946	125	18	before	before	ADP
ajlm-1946	125	19	the	the	DET
ajlm-1946	125	20	onset	onset	NOUN
ajlm-1946	125	21	of	of	ADP
ajlm-1946	125	22	the	the	DET
ajlm-1946	125	23	later	late	ADJ
ajlm-1946	125	24	features	feature	NOUN
ajlm-1946	125	25	,	,	PUNCT
ajlm-1946	125	26	such	such	ADJ
ajlm-1946	125	27	as	as	ADP
ajlm-1946	125	28	neuropathy	neuropathy	ADJ
ajlm-1946	125	29	and	and	CCONJ
ajlm-1946	125	30	atherosclerosis	atherosclerosis	NOUN
ajlm-1946	125	31	.	.	PUNCT
ajlm-1946	126	1	porphyrias	porphyria	NOUN
ajlm-1946	126	2	the	the	DET
ajlm-1946	126	3	porphyrias	porphyria	NOUN
ajlm-1946	126	4	are	be	AUX
ajlm-1946	126	5	a	a	DET
ajlm-1946	126	6	group	group	NOUN
ajlm-1946	126	7	of	of	ADP
ajlm-1946	126	8	iems	iem	NOUN
ajlm-1946	126	9	associated	associate	VERB
ajlm-1946	126	10	with	with	ADP
ajlm-1946	126	11	the	the	DET
ajlm-1946	126	12	absence	absence	NOUN
ajlm-1946	126	13	of	of	ADP
ajlm-1946	126	14	genes	gene	NOUN
ajlm-1946	126	15	encoding	encode	VERB
ajlm-1946	126	16	enzymes	enzyme	NOUN
ajlm-1946	126	17	that	that	PRON
ajlm-1946	126	18	catalyse	catalyse	VERB
ajlm-1946	126	19	reactions	reaction	NOUN
ajlm-1946	126	20	in	in	ADP
ajlm-1946	126	21	the	the	DET
ajlm-1946	126	22	haem	haem	NOUN
ajlm-1946	126	23	biosynthetic	biosynthetic	ADJ
ajlm-1946	126	24	pathway	pathway	NOUN
ajlm-1946	126	25	(	(	PUNCT
ajlm-1946	126	26	porphyria	porphyria	PROPN
ajlm-1946	126	27	means	mean	VERB
ajlm-1946	126	28	purple	purple	ADJ
ajlm-1946	126	29	)	)	PUNCT
ajlm-1946	126	30	.	.	PUNCT
ajlm-1946	127	1	the	the	DET
ajlm-1946	127	2	porphyrias	porphyria	NOUN
ajlm-1946	127	3	are	be	AUX
ajlm-1946	127	4	characterised	characterise	VERB
ajlm-1946	127	5	by	by	ADP
ajlm-1946	127	6	increased	increase	VERB
ajlm-1946	127	7	production	production	NOUN
ajlm-1946	127	8	and	and	CCONJ
ajlm-1946	127	9	excretion	excretion	NOUN
ajlm-1946	127	10	of	of	ADP
ajlm-1946	127	11	porphyrin	porphyrin	NOUN
ajlm-1946	127	12	precursors	precursor	NOUN
ajlm-1946	127	13	(	(	PUNCT
ajlm-1946	127	14	delta	delta	NOUN
ajlm-1946	127	15	aminolaevulinic	aminolaevulinic	NOUN
ajlm-1946	127	16	acid	acid	PROPN
ajlm-1946	127	17	and	and	CCONJ
ajlm-1946	127	18	porphobilinogen	porphobilinogen	NOUN
ajlm-1946	127	19	)	)	PUNCT
ajlm-1946	127	20	.	.	PUNCT
ajlm-1946	128	1	most	most	ADJ
ajlm-1946	128	2	are	be	AUX
ajlm-1946	128	3	inherited	inherit	VERB
ajlm-1946	128	4	as	as	ADP
ajlm-1946	128	5	autosomal	autosomal	ADJ
ajlm-1946	128	6	dominant	dominant	ADJ
ajlm-1946	128	7	traits	trait	NOUN
ajlm-1946	128	8	and	and	CCONJ
ajlm-1946	128	9	are	be	AUX
ajlm-1946	128	10	classified	classify	VERB
ajlm-1946	128	11	into	into	ADP
ajlm-1946	128	12	three	three	NUM
ajlm-1946	128	13	broad	broad	ADJ
ajlm-1946	128	14	groups	group	NOUN
ajlm-1946	128	15	:	:	PUNCT
ajlm-1946	128	16	hepatic	hepatic	ADJ
ajlm-1946	128	17	porphyrias	porphyria	NOUN
ajlm-1946	128	18	,	,	PUNCT
ajlm-1946	128	19	erythropoietic	erythropoietic	ADJ
ajlm-1946	128	20	porphyrias	porphyria	NOUN
ajlm-1946	128	21	,	,	PUNCT
ajlm-1946	128	22	and	and	CCONJ
ajlm-1946	128	23	combined	combined	ADJ
ajlm-1946	128	24	erythropoietic	erythropoietic	ADJ
ajlm-1946	128	25	and	and	CCONJ
ajlm-1946	128	26	hepatic	hepatic	ADJ
ajlm-1946	128	27	abnormalities	abnormality	NOUN
ajlm-1946	128	28	.	.	PUNCT
ajlm-1946	129	1	the	the	DET
ajlm-1946	129	2	classification	classification	NOUN
ajlm-1946	129	3	is	be	AUX
ajlm-1946	129	4	based	base	VERB
ajlm-1946	129	5	on	on	ADP
ajlm-1946	129	6	the	the	DET
ajlm-1946	129	7	major	major	ADJ
ajlm-1946	129	8	site	site	NOUN
ajlm-1946	129	9	where	where	SCONJ
ajlm-1946	129	10	the	the	DET
ajlm-1946	129	11	enzyme	enzyme	NOUN
ajlm-1946	129	12	deficiency	deficiency	NOUN
ajlm-1946	129	13	is	be	AUX
ajlm-1946	129	14	manifested	manifest	VERB
ajlm-1946	129	15	.	.	PUNCT
ajlm-1946	130	1	the	the	DET
ajlm-1946	130	2	clinical	clinical	ADJ
ajlm-1946	130	3	manifestations	manifestation	NOUN
ajlm-1946	130	4	of	of	ADP
ajlm-1946	130	5	porphyrias	porphyria	NOUN
ajlm-1946	130	6	vary	vary	VERB
ajlm-1946	130	7	and	and	CCONJ
ajlm-1946	130	8	are	be	AUX
ajlm-1946	130	9	not	not	PART
ajlm-1946	130	10	usually	usually	ADV
ajlm-1946	130	11	associated	associate	VERB
ajlm-1946	130	12	with	with	ADP
ajlm-1946	130	13	anaemia	anaemia	NOUN
ajlm-1946	130	14	.	.	PUNCT
ajlm-1946	131	1	one	one	NUM
ajlm-1946	131	2	of	of	ADP
ajlm-1946	131	3	the	the	DET
ajlm-1946	131	4	most	most	ADV
ajlm-1946	131	5	common	common	ADJ
ajlm-1946	131	6	clinical	clinical	ADJ
ajlm-1946	131	7	manifestations	manifestation	NOUN
ajlm-1946	131	8	is	be	AUX
ajlm-1946	131	9	acute	acute	ADJ
ajlm-1946	131	10	intermittent	intermittent	ADJ
ajlm-1946	131	11	porphyria	porphyria	NOUN
ajlm-1946	131	12	,	,	PUNCT
ajlm-1946	131	13	which	which	PRON
ajlm-1946	131	14	is	be	AUX
ajlm-1946	131	15	an	an	DET
ajlm-1946	131	16	inherited	inherit	VERB
ajlm-1946	131	17	genetic	genetic	ADJ
ajlm-1946	131	18	disorder.25	disorder.25	NOUN
ajlm-1946	131	19	the	the	DET
ajlm-1946	131	20	biochemical	biochemical	ADJ
ajlm-1946	131	21	lesion	lesion	NOUN
ajlm-1946	131	22	in	in	ADP
ajlm-1946	131	23	acute	acute	ADJ
ajlm-1946	131	24	intermittent	intermittent	ADJ
ajlm-1946	131	25	porphyria	porphyria	NOUN
ajlm-1946	131	26	is	be	AUX
ajlm-1946	131	27	a	a	DET
ajlm-1946	131	28	lack	lack	NOUN
ajlm-1946	131	29	of	of	ADP
ajlm-1946	131	30	porphobilinogen	porphobilinogen	NOUN
ajlm-1946	131	31	deaminase	deaminase	NOUN
ajlm-1946	131	32	(	(	PUNCT
ajlm-1946	131	33	uroporphyrinogen-1	uroporphyrinogen-1	NOUN
ajlm-1946	131	34	-	-	PUNCT
ajlm-1946	131	35	synthetase	synthetase	NOUN
ajlm-1946	131	36	)	)	PUNCT
ajlm-1946	131	37	,	,	PUNCT
ajlm-1946	131	38	which	which	PRON
ajlm-1946	131	39	causes	cause	VERB
ajlm-1946	131	40	a	a	DET
ajlm-1946	131	41	secondary	secondary	ADJ
ajlm-1946	131	42	increase	increase	NOUN
ajlm-1946	131	43	in	in	ADP
ajlm-1946	131	44	aminolaevulinic	aminolaevulinic	ADJ
ajlm-1946	131	45	acid	acid	NOUN
ajlm-1946	131	46	synthase	synthase	NOUN
ajlm-1946	131	47	activity	activity	NOUN
ajlm-1946	131	48	(	(	PUNCT
ajlm-1946	131	49	negative	negative	ADJ
ajlm-1946	131	50	feedback	feedback	NOUN
ajlm-1946	131	51	mechanism	mechanism	NOUN
ajlm-1946	131	52	abolished	abolish	VERB
ajlm-1946	131	53	)	)	PUNCT
ajlm-1946	131	54	.	.	PUNCT
ajlm-1946	132	1	delta	delta	NOUN
ajlm-1946	132	2	aminolaevulinic	aminolaevulinic	NOUN
ajlm-1946	132	3	acid	acid	PROPN
ajlm-1946	132	4	and	and	CCONJ
ajlm-1946	132	5	porphobilinogen	porphobilinogen	NOUN
ajlm-1946	132	6	,	,	PUNCT
ajlm-1946	132	7	two	two	NUM
ajlm-1946	132	8	key	key	ADJ
ajlm-1946	132	9	intermediates	intermediate	NOUN
ajlm-1946	132	10	in	in	ADP
ajlm-1946	132	11	the	the	DET
ajlm-1946	132	12	haem	haem	NOUN
ajlm-1946	132	13	biosynthetic	biosynthetic	ADJ
ajlm-1946	132	14	pathway	pathway	NOUN
ajlm-1946	132	15	,	,	PUNCT
ajlm-1946	132	16	are	be	AUX
ajlm-1946	132	17	elevated	elevate	VERB
ajlm-1946	132	18	in	in	ADP
ajlm-1946	132	19	blood	blood	NOUN
ajlm-1946	132	20	and	and	CCONJ
ajlm-1946	132	21	urine	urine	NOUN
ajlm-1946	132	22	of	of	ADP
ajlm-1946	132	23	patients	patient	NOUN
ajlm-1946	132	24	with	with	ADP
ajlm-1946	132	25	porphyrias	porphyria	NOUN
ajlm-1946	132	26	.	.	PUNCT
ajlm-1946	133	1	the	the	DET
ajlm-1946	133	2	porphobilinogen	porphobilinogen	NOUN
ajlm-1946	133	3	assay	assay	NOUN
ajlm-1946	133	4	should	should	AUX
ajlm-1946	133	5	be	be	AUX
ajlm-1946	133	6	conducted	conduct	VERB
ajlm-1946	133	7	using	use	VERB
ajlm-1946	133	8	fresh	fresh	ADJ
ajlm-1946	133	9	urine	urine	NOUN
ajlm-1946	133	10	samples	sample	NOUN
ajlm-1946	133	11	transported	transport	VERB
ajlm-1946	133	12	in	in	ADP
ajlm-1946	133	13	dark	dark	ADJ
ajlm-1946	133	14	bottles	bottle	NOUN
ajlm-1946	133	15	.	.	PUNCT
ajlm-1946	134	1	the	the	DET
ajlm-1946	134	2	key	key	ADJ
ajlm-1946	134	3	reagent	reagent	NOUN
ajlm-1946	134	4	required	require	VERB
ajlm-1946	134	5	for	for	ADP
ajlm-1946	134	6	porphobilinogen	porphobilinogen	NOUN
ajlm-1946	134	7	is	be	AUX
ajlm-1946	134	8	p	p	NOUN
ajlm-1946	134	9	-	-	PUNCT
ajlm-1946	134	10	dimethylaminobenzaldehyde	dimethylaminobenzaldehyde	NOUN
ajlm-1946	134	11	(	(	PUNCT
ajlm-1946	134	12	ehrlich	ehrlich	NOUN
ajlm-1946	134	13	’s	’s	PART
ajlm-1946	134	14	reaction	reaction	NOUN
ajlm-1946	134	15	)	)	PUNCT
ajlm-1946	134	16	,	,	PUNCT
ajlm-1946	134	17	which	which	PRON
ajlm-1946	134	18	is	be	AUX
ajlm-1946	134	19	commonly	commonly	ADV
ajlm-1946	134	20	employed	employ	VERB
ajlm-1946	134	21	in	in	ADP
ajlm-1946	134	22	testing	testing	NOUN
ajlm-1946	134	23	for	for	ADP
ajlm-1946	134	24	urobilinogen	urobilinogen	NOUN
ajlm-1946	134	25	,	,	PUNCT
ajlm-1946	134	26	a	a	DET
ajlm-1946	134	27	basic	basic	ADJ
ajlm-1946	134	28	test	test	NOUN
ajlm-1946	134	29	conducted	conduct	VERB
ajlm-1946	134	30	in	in	ADP
ajlm-1946	134	31	all	all	DET
ajlm-1946	134	32	laboratories	laboratory	NOUN
ajlm-1946	134	33	.	.	PUNCT
ajlm-1946	135	1	elevated	elevated	ADJ
ajlm-1946	135	2	urinary	urinary	ADJ
ajlm-1946	135	3	porphobilinogen	porphobilinogen	NOUN
ajlm-1946	135	4	excretion	excretion	NOUN
ajlm-1946	135	5	confirms	confirm	VERB
ajlm-1946	135	6	the	the	DET
ajlm-1946	135	7	presence	presence	NOUN
ajlm-1946	135	8	of	of	ADP
ajlm-1946	135	9	hepatic	hepatic	ADJ
ajlm-1946	135	10	porphyria	porphyria	NOUN
ajlm-1946	135	11	.	.	PUNCT
ajlm-1946	136	1	if	if	SCONJ
ajlm-1946	136	2	porphobilinogen	porphobilinogen	NOUN
ajlm-1946	136	3	excretion	excretion	NOUN
ajlm-1946	136	4	exceeds	exceed	NOUN
ajlm-1946	136	5	aminolaevulinic	aminolaevulinic	ADJ
ajlm-1946	136	6	acid	acid	NOUN
ajlm-1946	136	7	excretion	excretion	NOUN
ajlm-1946	136	8	,	,	PUNCT
ajlm-1946	136	9	lead	lead	ADJ
ajlm-1946	136	10	poisoning	poisoning	NOUN
ajlm-1946	136	11	can	can	AUX
ajlm-1946	136	12	be	be	AUX
ajlm-1946	136	13	ruled	rule	VERB
ajlm-1946	136	14	out.26,27	out.26,27	PRON
ajlm-1946	136	15	acute	acute	ADJ
ajlm-1946	136	16	abdominal	abdominal	ADJ
ajlm-1946	136	17	pain	pain	NOUN
ajlm-1946	136	18	and	and	CCONJ
ajlm-1946	136	19	neurological	neurological	ADJ
ajlm-1946	136	20	manifestations	manifestation	NOUN
ajlm-1946	136	21	,	,	PUNCT
ajlm-1946	136	22	such	such	ADJ
ajlm-1946	136	23	as	as	ADP
ajlm-1946	136	24	sensory	sensory	ADJ
ajlm-1946	136	25	and	and	CCONJ
ajlm-1946	136	26	motor	motor	NOUN
ajlm-1946	136	27	disturbances	disturbance	NOUN
ajlm-1946	136	28	,	,	PUNCT
ajlm-1946	136	29	including	include	VERB
ajlm-1946	136	30	confusion	confusion	NOUN
ajlm-1946	136	31	and	and	CCONJ
ajlm-1946	136	32	agitation	agitation	NOUN
ajlm-1946	136	33	,	,	PUNCT
ajlm-1946	136	34	are	be	AUX
ajlm-1946	136	35	among	among	ADP
ajlm-1946	136	36	the	the	DET
ajlm-1946	136	37	clinical	clinical	ADJ
ajlm-1946	136	38	symptoms	symptom	NOUN
ajlm-1946	136	39	that	that	PRON
ajlm-1946	136	40	may	may	AUX
ajlm-1946	136	41	be	be	AUX
ajlm-1946	136	42	intermittent	intermittent	ADJ
ajlm-1946	136	43	and	and	CCONJ
ajlm-1946	136	44	vague	vague	ADJ
ajlm-1946	136	45	(	(	PUNCT
ajlm-1946	136	46	dubbed	dub	VERB
ajlm-1946	136	47	‘	'	PUNCT
ajlm-1946	136	48	little	little	ADJ
ajlm-1946	136	49	imitators	imitator	NOUN
ajlm-1946	136	50	’	'	PUNCT
ajlm-1946	136	51	)	)	PUNCT
ajlm-1946	136	52	.	.	PUNCT
ajlm-1946	137	1	a	a	DET
ajlm-1946	137	2	simple	simple	ADJ
ajlm-1946	137	3	ultraviolet	ultraviolet	ADJ
ajlm-1946	137	4	fluorescence	fluorescence	NOUN
ajlm-1946	137	5	test	test	NOUN
ajlm-1946	137	6	with	with	ADP
ajlm-1946	137	7	a	a	DET
ajlm-1946	137	8	wood	wood	NOUN
ajlm-1946	137	9	’s	’s	PART
ajlm-1946	137	10	lamp	lamp	NOUN
ajlm-1946	137	11	to	to	PART
ajlm-1946	137	12	demonstrate	demonstrate	VERB
ajlm-1946	137	13	porphyrin	porphyrin	NOUN
ajlm-1946	137	14	is	be	AUX
ajlm-1946	137	15	also	also	ADV
ajlm-1946	137	16	useful	useful	ADJ
ajlm-1946	137	17	and	and	CCONJ
ajlm-1946	137	18	easily	easily	ADV
ajlm-1946	137	19	accessible	accessible	ADJ
ajlm-1946	137	20	.	.	PUNCT
ajlm-1946	138	1	congenital	congenital	ADJ
ajlm-1946	138	2	hypothyroidism	hypothyroidism	NOUN
ajlm-1946	138	3	all	all	DET
ajlm-1946	138	4	newborns	newborn	NOUN
ajlm-1946	138	5	in	in	ADP
ajlm-1946	138	6	every	every	DET
ajlm-1946	138	7	hospital	hospital	NOUN
ajlm-1946	138	8	should	should	AUX
ajlm-1946	138	9	be	be	AUX
ajlm-1946	138	10	screened	screen	VERB
ajlm-1946	138	11	for	for	ADP
ajlm-1946	138	12	congenital	congenital	ADJ
ajlm-1946	138	13	hypothyroidism	hypothyroidism	NOUN
ajlm-1946	138	14	before	before	SCONJ
ajlm-1946	138	15	they	they	PRON
ajlm-1946	138	16	are	be	AUX
ajlm-1946	138	17	discharged	discharge	VERB
ajlm-1946	138	18	.	.	PUNCT
ajlm-1946	139	1	congenital	congenital	ADJ
ajlm-1946	139	2	hypothyroidism	hypothyroidism	NOUN
ajlm-1946	139	3	is	be	AUX
ajlm-1946	139	4	a	a	DET
ajlm-1946	139	5	clinically	clinically	ADV
ajlm-1946	139	6	significant	significant	ADJ
ajlm-1946	139	7	disorder	disorder	NOUN
ajlm-1946	139	8	,	,	PUNCT
ajlm-1946	139	9	especially	especially	ADV
ajlm-1946	139	10	due	due	ADP
ajlm-1946	139	11	to	to	ADP
ajlm-1946	139	12	its	its	PRON
ajlm-1946	139	13	adverse	adverse	ADJ
ajlm-1946	139	14	neurological	neurological	ADJ
ajlm-1946	139	15	outcome	outcome	NOUN
ajlm-1946	139	16	.	.	PUNCT
ajlm-1946	140	1	this	this	DET
ajlm-1946	140	2	adverse	adverse	ADJ
ajlm-1946	140	3	neurological	neurological	ADJ
ajlm-1946	140	4	outcome	outcome	NOUN
ajlm-1946	140	5	can	can	AUX
ajlm-1946	140	6	however	however	ADV
ajlm-1946	140	7	be	be	AUX
ajlm-1946	140	8	easily	easily	ADV
ajlm-1946	140	9	reversed	reverse	VERB
ajlm-1946	140	10	if	if	SCONJ
ajlm-1946	140	11	detected	detect	VERB
ajlm-1946	140	12	early	early	ADV
ajlm-1946	140	13	.	.	PUNCT
ajlm-1946	141	1	most	most	ADJ
ajlm-1946	141	2	infants	infant	NOUN
ajlm-1946	141	3	are	be	AUX
ajlm-1946	141	4	asymptomatic	asymptomatic	ADJ
ajlm-1946	141	5	at	at	ADP
ajlm-1946	141	6	birth	birth	NOUN
ajlm-1946	141	7	because	because	SCONJ
ajlm-1946	141	8	thyroxin	thyroxin	NOUN
ajlm-1946	141	9	from	from	ADP
ajlm-1946	141	10	the	the	DET
ajlm-1946	141	11	maternal	maternal	ADJ
ajlm-1946	141	12	circulation	circulation	NOUN
ajlm-1946	141	13	diffuses	diffuse	VERB
ajlm-1946	141	14	across	across	ADP
ajlm-1946	141	15	the	the	DET
ajlm-1946	141	16	placenta	placenta	NOUN
ajlm-1946	141	17	.	.	PUNCT
ajlm-1946	142	1	congenital	congenital	ADJ
ajlm-1946	142	2	hypothyroidism	hypothyroidism	NOUN
ajlm-1946	142	3	may	may	AUX
ajlm-1946	142	4	be	be	AUX
ajlm-1946	142	5	suggested	suggest	VERB
ajlm-1946	142	6	by	by	ADP
ajlm-1946	142	7	clinical	clinical	ADJ
ajlm-1946	142	8	features	feature	NOUN
ajlm-1946	142	9	such	such	ADJ
ajlm-1946	142	10	as	as	ADP
ajlm-1946	142	11	lethargy	lethargy	NOUN
ajlm-1946	142	12	,	,	PUNCT
ajlm-1946	142	13	umbilical	umbilical	ADJ
ajlm-1946	142	14	hernia	hernia	NOUN
ajlm-1946	142	15	,	,	PUNCT
ajlm-1946	142	16	slow	slow	ADJ
ajlm-1946	142	17	movement	movement	NOUN
ajlm-1946	142	18	,	,	PUNCT
ajlm-1946	142	19	hoarse	hoarse	ADJ
ajlm-1946	142	20	cry	cry	NOUN
ajlm-1946	142	21	,	,	PUNCT
ajlm-1946	142	22	macroglossia	macroglossia	NOUN
ajlm-1946	142	23	,	,	PUNCT
ajlm-1946	142	24	hypothermia	hypothermia	NOUN
ajlm-1946	142	25	,	,	PUNCT
ajlm-1946	142	26	and	and	CCONJ
ajlm-1946	142	27	hypotonia.28	hypotonia.28	VERB
ajlm-1946	142	28	a	a	DET
ajlm-1946	142	29	simple	simple	ADJ
ajlm-1946	142	30	panel	panel	NOUN
ajlm-1946	142	31	of	of	ADP
ajlm-1946	142	32	thyroid	thyroid	NOUN
ajlm-1946	142	33	function	function	NOUN
ajlm-1946	142	34	tests	test	NOUN
ajlm-1946	142	35	,	,	PUNCT
ajlm-1946	142	36	especially	especially	ADV
ajlm-1946	142	37	thyroid	thyroid	NOUN
ajlm-1946	142	38	-	-	PUNCT
ajlm-1946	142	39	stimulating	stimulate	VERB
ajlm-1946	142	40	hormone	hormone	NOUN
ajlm-1946	142	41	,	,	PUNCT
ajlm-1946	142	42	are	be	AUX
ajlm-1946	142	43	useful	useful	ADJ
ajlm-1946	142	44	investigations	investigation	NOUN
ajlm-1946	142	45	to	to	PART
ajlm-1946	142	46	confirm	confirm	VERB
ajlm-1946	142	47	these	these	DET
ajlm-1946	142	48	clinical	clinical	ADJ
ajlm-1946	142	49	findings	finding	NOUN
ajlm-1946	142	50	where	where	SCONJ
ajlm-1946	142	51	they	they	PRON
ajlm-1946	142	52	manifest	manifest	VERB
ajlm-1946	142	53	.	.	PUNCT
ajlm-1946	143	1	the	the	DET
ajlm-1946	143	2	thyroid	thyroid	NOUN
ajlm-1946	143	3	-	-	PUNCT
ajlm-1946	143	4	stimulating	stimulate	VERB
ajlm-1946	143	5	hormone	hormone	NOUN
ajlm-1946	143	6	value	value	NOUN
ajlm-1946	143	7	is	be	AUX
ajlm-1946	143	8	particularly	particularly	ADV
ajlm-1946	143	9	important	important	ADJ
ajlm-1946	143	10	as	as	SCONJ
ajlm-1946	143	11	it	it	PRON
ajlm-1946	143	12	is	be	AUX
ajlm-1946	143	13	very	very	ADV
ajlm-1946	143	14	sensitive.29	sensitive.29	NOUN
ajlm-1946	143	15	congenital	congenital	ADJ
ajlm-1946	143	16	adrenal	adrenal	ADJ
ajlm-1946	143	17	hyperplasia	hyperplasia	NOUN
ajlm-1946	143	18	congenital	congenital	ADJ
ajlm-1946	143	19	adrenal	adrenal	ADJ
ajlm-1946	143	20	hyperplasia	hyperplasia	NOUN
ajlm-1946	143	21	is	be	AUX
ajlm-1946	143	22	an	an	DET
ajlm-1946	143	23	inherited	inherit	VERB
ajlm-1946	143	24	endocrinopathy	endocrinopathy	NOUN
ajlm-1946	143	25	caused	cause	VERB
ajlm-1946	143	26	by	by	ADP
ajlm-1946	143	27	the	the	DET
ajlm-1946	143	28	genetic	genetic	ADJ
ajlm-1946	143	29	absence	absence	NOUN
ajlm-1946	143	30	of	of	ADP
ajlm-1946	143	31	certain	certain	ADJ
ajlm-1946	143	32	enzymes	enzyme	NOUN
ajlm-1946	143	33	involved	involve	VERB
ajlm-1946	143	34	in	in	ADP
ajlm-1946	143	35	steroidogenesis	steroidogenesis	NOUN
ajlm-1946	143	36	,	,	PUNCT
ajlm-1946	143	37	particularly	particularly	ADV
ajlm-1946	143	38	the	the	DET
ajlm-1946	143	39	cortisol	cortisol	ADJ
ajlm-1946	143	40	pathway	pathway	NOUN
ajlm-1946	143	41	.	.	PUNCT
ajlm-1946	144	1	due	due	ADP
ajlm-1946	144	2	to	to	ADP
ajlm-1946	144	3	the	the	DET
ajlm-1946	144	4	lack	lack	NOUN
ajlm-1946	144	5	of	of	ADP
ajlm-1946	144	6	a	a	DET
ajlm-1946	144	7	negative	negative	ADJ
ajlm-1946	144	8	feedback	feedback	NOUN
ajlm-1946	144	9	mechanism	mechanism	NOUN
ajlm-1946	144	10	,	,	PUNCT
ajlm-1946	144	11	this	this	DET
ajlm-1946	144	12	biochemical	biochemical	ADJ
ajlm-1946	144	13	lesion	lesion	NOUN
ajlm-1946	144	14	results	result	VERB
ajlm-1946	144	15	in	in	ADP
ajlm-1946	144	16	the	the	DET
ajlm-1946	144	17	accumulation	accumulation	NOUN
ajlm-1946	144	18	of	of	ADP
ajlm-1946	144	19	intermediates	intermediate	NOUN
ajlm-1946	144	20	,	,	PUNCT
ajlm-1946	144	21	some	some	PRON
ajlm-1946	144	22	of	of	ADP
ajlm-1946	144	23	which	which	PRON
ajlm-1946	144	24	are	be	AUX
ajlm-1946	144	25	potent	potent	ADJ
ajlm-1946	144	26	androgens	androgen	NOUN
ajlm-1946	144	27	such	such	ADJ
ajlm-1946	144	28	as	as	ADP
ajlm-1946	144	29	17	17	NUM
ajlm-1946	144	30	-	-	PUNCT
ajlm-1946	144	31	hydroxyprogesterone	hydroxyprogesterone	NOUN
ajlm-1946	144	32	,	,	PUNCT
ajlm-1946	144	33	which	which	PRON
ajlm-1946	144	34	accounts	account	VERB
ajlm-1946	144	35	for	for	ADP
ajlm-1946	144	36	virilism	virilism	NOUN
ajlm-1946	144	37	and	and	CCONJ
ajlm-1946	144	38	genital	genital	ADJ
ajlm-1946	144	39	ambiguity	ambiguity	NOUN
ajlm-1946	144	40	in	in	ADP
ajlm-1946	144	41	affected	affected	ADJ
ajlm-1946	144	42	patients	patient	NOUN
ajlm-1946	144	43	.	.	PUNCT
ajlm-1946	145	1	the	the	DET
ajlm-1946	145	2	most	most	ADV
ajlm-1946	145	3	common	common	ADJ
ajlm-1946	145	4	of	of	ADP
ajlm-1946	145	5	these	these	DET
ajlm-1946	145	6	enzyme	enzyme	NOUN
ajlm-1946	145	7	deficiencies	deficiency	NOUN
ajlm-1946	145	8	is	be	AUX
ajlm-1946	145	9	a	a	DET
ajlm-1946	145	10	21	21	NUM
ajlm-1946	145	11	-	-	PUNCT
ajlm-1946	145	12	hydroxylase	hydroxylase	NOUN
ajlm-1946	145	13	deficiency	deficiency	NOUN
ajlm-1946	145	14	.	.	PUNCT
ajlm-1946	146	1	the	the	DET
ajlm-1946	146	2	enzyme	enzyme	NOUN
ajlm-1946	146	3	responsible	responsible	ADJ
ajlm-1946	146	4	for	for	ADP
ajlm-1946	146	5	producing	produce	VERB
ajlm-1946	146	6	the	the	DET
ajlm-1946	146	7	mineralocorticoid	mineralocorticoid	NOUN
ajlm-1946	146	8	aldosterone	aldosterone	NOUN
ajlm-1946	146	9	may	may	AUX
ajlm-1946	146	10	also	also	ADV
ajlm-1946	146	11	be	be	AUX
ajlm-1946	146	12	altered	alter	VERB
ajlm-1946	146	13	,	,	PUNCT
ajlm-1946	146	14	which	which	PRON
ajlm-1946	146	15	could	could	AUX
ajlm-1946	146	16	explain	explain	VERB
ajlm-1946	146	17	the	the	DET
ajlm-1946	146	18	salt	salt	NOUN
ajlm-1946	146	19	-	-	PUNCT
ajlm-1946	146	20	loss	loss	NOUN
ajlm-1946	146	21	presentation	presentation	NOUN
ajlm-1946	146	22	(	(	PUNCT
ajlm-1946	146	23	hyponatraemia	hyponatraemia	NOUN
ajlm-1946	146	24	and	and	CCONJ
ajlm-1946	146	25	hyperkalaemia	hyperkalaemia	NOUN
ajlm-1946	146	26	)	)	PUNCT
ajlm-1946	146	27	.	.	PUNCT
ajlm-1946	147	1	some	some	PRON
ajlm-1946	147	2	of	of	ADP
ajlm-1946	147	3	the	the	DET
ajlm-1946	147	4	key	key	ADJ
ajlm-1946	147	5	clinical	clinical	ADJ
ajlm-1946	147	6	and	and	CCONJ
ajlm-1946	147	7	biochemical	biochemical	ADJ
ajlm-1946	147	8	features	feature	NOUN
ajlm-1946	147	9	include	include	VERB
ajlm-1946	147	10	precocious	precocious	ADJ
ajlm-1946	147	11	growth	growth	NOUN
ajlm-1946	147	12	,	,	PUNCT
ajlm-1946	147	13	increased	increase	VERB
ajlm-1946	147	14	testosterone	testosterone	NOUN
ajlm-1946	147	15	,	,	PUNCT
ajlm-1946	147	16	increased	increase	VERB
ajlm-1946	147	17	17	17	NUM
ajlm-1946	147	18	-	-	PUNCT
ajlm-1946	147	19	hydroxyprogesterone	hydroxyprogesterone	ADJ
ajlm-1946	147	20	,	,	PUNCT
ajlm-1946	147	21	suboptimal	suboptimal	ADJ
ajlm-1946	147	22	cortisol	cortisol	ADJ
ajlm-1946	147	23	level	level	NOUN
ajlm-1946	147	24	with	with	ADP
ajlm-1946	147	25	basal	basal	NOUN
ajlm-1946	147	26	and	and	CCONJ
ajlm-1946	147	27	adrenocorticotropic	adrenocorticotropic	NOUN
ajlm-1946	147	28	hormone	hormone	NOUN
ajlm-1946	147	29	stimulation	stimulation	NOUN
ajlm-1946	147	30	tests	test	NOUN
ajlm-1946	147	31	,	,	PUNCT
ajlm-1946	147	32	small	small	ADJ
ajlm-1946	147	33	testes	testis	NOUN
ajlm-1946	147	34	,	,	PUNCT
ajlm-1946	147	35	and	and	CCONJ
ajlm-1946	147	36	shock	shock	NOUN
ajlm-1946	147	37	.	.	PUNCT
ajlm-1946	148	1	though	though	SCONJ
ajlm-1946	148	2	genetic	genetic	ADJ
ajlm-1946	148	3	tests	test	NOUN
ajlm-1946	148	4	like	like	ADP
ajlm-1946	148	5	karyotyping	karyotyping	NOUN
ajlm-1946	148	6	may	may	AUX
ajlm-1946	148	7	be	be	AUX
ajlm-1946	148	8	used	use	VERB
ajlm-1946	148	9	to	to	PART
ajlm-1946	148	10	detect	detect	VERB
ajlm-1946	148	11	congenital	congenital	ADJ
ajlm-1946	148	12	adrenal	adrenal	ADJ
ajlm-1946	148	13	hyperplasia	hyperplasia	NOUN
ajlm-1946	148	14	,	,	PUNCT
ajlm-1946	148	15	basic	basic	ADJ
ajlm-1946	148	16	tests	test	NOUN
ajlm-1946	148	17	such	such	ADJ
ajlm-1946	148	18	as	as	ADP
ajlm-1946	148	19	sodium	sodium	NOUN
ajlm-1946	148	20	assay	assay	NOUN
ajlm-1946	148	21	(	(	PUNCT
ajlm-1946	148	22	hyponatraemia	hyponatraemia	NOUN
ajlm-1946	148	23	)	)	PUNCT
ajlm-1946	148	24	,	,	PUNCT
ajlm-1946	148	25	potassium	potassium	NOUN
ajlm-1946	148	26	assay	assay	NOUN
ajlm-1946	148	27	(	(	PUNCT
ajlm-1946	148	28	hyperkalaemia	hyperkalaemia	NOUN
ajlm-1946	148	29	)	)	PUNCT
ajlm-1946	148	30	,	,	PUNCT
ajlm-1946	148	31	urinary	urinary	ADJ
ajlm-1946	148	32	sodium	sodium	NOUN
ajlm-1946	148	33	test	test	NOUN
ajlm-1946	148	34	(	(	PUNCT
ajlm-1946	148	35	increased	increase	VERB
ajlm-1946	148	36	sodium	sodium	NOUN
ajlm-1946	148	37	level	level	NOUN
ajlm-1946	148	38	)	)	PUNCT
ajlm-1946	148	39	,	,	PUNCT
ajlm-1946	148	40	and	and	CCONJ
ajlm-1946	148	41	plasma	plasma	NOUN
ajlm-1946	148	42	renin	renin	ADJ
ajlm-1946	148	43	activity	activity	NOUN
ajlm-1946	148	44	(	(	PUNCT
ajlm-1946	148	45	increased	increase	VERB
ajlm-1946	148	46	plasma	plasma	NOUN
ajlm-1946	148	47	renin	renin	ADJ
ajlm-1946	148	48	activity	activity	NOUN
ajlm-1946	148	49	level	level	NOUN
ajlm-1946	148	50	)	)	PUNCT
ajlm-1946	148	51	may	may	AUX
ajlm-1946	148	52	be	be	AUX
ajlm-1946	148	53	within	within	ADP
ajlm-1946	148	54	the	the	DET
ajlm-1946	148	55	reach	reach	NOUN
ajlm-1946	148	56	of	of	ADP
ajlm-1946	148	57	laboratories	laboratory	NOUN
ajlm-1946	148	58	in	in	ADP
ajlm-1946	148	59	resource	resource	NOUN
ajlm-1946	148	60	-	-	PUNCT
ajlm-1946	148	61	limited	limit	VERB
ajlm-1946	148	62	countries	country	NOUN
ajlm-1946	148	63	.	.	PUNCT
ajlm-1946	149	1	owing	owe	VERB
ajlm-1946	149	2	to	to	ADP
ajlm-1946	149	3	the	the	DET
ajlm-1946	149	4	severity	severity	NOUN
ajlm-1946	149	5	of	of	ADP
ajlm-1946	149	6	congenital	congenital	ADJ
ajlm-1946	149	7	adrenal	adrenal	ADJ
ajlm-1946	149	8	hyperplasia	hyperplasia	NOUN
ajlm-1946	149	9	,	,	PUNCT
ajlm-1946	149	10	we	we	PRON
ajlm-1946	149	11	think	think	VERB
ajlm-1946	149	12	it	it	PRON
ajlm-1946	149	13	should	should	AUX
ajlm-1946	149	14	be	be	AUX
ajlm-1946	149	15	a	a	DET
ajlm-1946	149	16	candidate	candidate	NOUN
ajlm-1946	149	17	for	for	ADP
ajlm-1946	149	18	newborn	newborn	ADJ
ajlm-1946	149	19	screening	screening	NOUN
ajlm-1946	149	20	programs	program	NOUN
ajlm-1946	149	21	in	in	ADP
ajlm-1946	149	22	these	these	DET
ajlm-1946	149	23	countries	country	NOUN
ajlm-1946	149	24	.	.	PUNCT
ajlm-1946	150	1	inherited	inherit	VERB
ajlm-1946	150	2	hyperbilirubinaemias	hyperbilirubinaemias	NOUN
ajlm-1946	150	3	congenital	congenital	ADJ
ajlm-1946	150	4	hyperbilirubinaemias	hyperbilirubinaemia	NOUN
ajlm-1946	150	5	arise	arise	VERB
ajlm-1946	150	6	from	from	ADP
ajlm-1946	150	7	the	the	DET
ajlm-1946	150	8	absence	absence	NOUN
ajlm-1946	150	9	of	of	ADP
ajlm-1946	150	10	enzymes	enzyme	NOUN
ajlm-1946	150	11	involved	involve	VERB
ajlm-1946	150	12	in	in	ADP
ajlm-1946	150	13	bilirubin	bilirubin	NOUN
ajlm-1946	150	14	metabolism	metabolism	NOUN
ajlm-1946	150	15	and	and	CCONJ
ajlm-1946	150	16	transportation	transportation	NOUN
ajlm-1946	150	17	,	,	PUNCT
ajlm-1946	150	18	especially	especially	ADV
ajlm-1946	150	19	uridine	uridine	ADJ
ajlm-1946	150	20	diphosphate	diphosphate	NOUN
ajlm-1946	150	21	glycosyltransferase	glycosyltransferase	NOUN
ajlm-1946	150	22	.	.	PUNCT
ajlm-1946	151	1	some	some	PRON
ajlm-1946	151	2	of	of	ADP
ajlm-1946	151	3	these	these	DET
ajlm-1946	151	4	hyperbilirubinaemias	hyperbilirubinaemia	NOUN
ajlm-1946	151	5	include	include	VERB
ajlm-1946	151	6	crigler	crigler	NOUN
ajlm-1946	151	7	najjar	najjar	PROPN
ajlm-1946	151	8	,	,	PUNCT
ajlm-1946	151	9	gilbert	gilbert	PROPN
ajlm-1946	151	10	,	,	PUNCT
ajlm-1946	151	11	dubin	dubin	PROPN
ajlm-1946	151	12	-	-	PUNCT
ajlm-1946	151	13	johnson	johnson	PROPN
ajlm-1946	151	14	,	,	PUNCT
ajlm-1946	151	15	and	and	CCONJ
ajlm-1946	151	16	rotors	rotor	NOUN
ajlm-1946	151	17	.	.	PUNCT
ajlm-1946	152	1	these	these	PRON
ajlm-1946	152	2	can	can	AUX
ajlm-1946	152	3	be	be	AUX
ajlm-1946	152	4	easily	easily	ADV
ajlm-1946	152	5	diagnosed	diagnose	VERB
ajlm-1946	152	6	by	by	ADP
ajlm-1946	152	7	basic	basic	ADJ
ajlm-1946	152	8	bilirubin	bilirubin	NOUN
ajlm-1946	152	9	determination	determination	NOUN
ajlm-1946	152	10	(	(	PUNCT
ajlm-1946	152	11	total	total	ADJ
ajlm-1946	152	12	and	and	CCONJ
ajlm-1946	152	13	conjugated	conjugate	VERB
ajlm-1946	152	14	)	)	PUNCT
ajlm-1946	152	15	and	and	CCONJ
ajlm-1946	152	16	related	relate	VERB
ajlm-1946	152	17	to	to	ADP
ajlm-1946	152	18	clinical	clinical	ADJ
ajlm-1946	152	19	presentation	presentation	NOUN
ajlm-1946	152	20	.	.	PUNCT
ajlm-1946	153	1	a	a	DET
ajlm-1946	153	2	combination	combination	NOUN
ajlm-1946	153	3	of	of	ADP
ajlm-1946	153	4	blood	blood	NOUN
ajlm-1946	153	5	and	and	CCONJ
ajlm-1946	153	6	urine	urine	NOUN
ajlm-1946	153	7	findings	finding	NOUN
ajlm-1946	153	8	helps	help	VERB
ajlm-1946	153	9	in	in	ADP
ajlm-1946	153	10	the	the	DET
ajlm-1946	153	11	differential	differential	ADJ
ajlm-1946	153	12	diagnosis	diagnosis	NOUN
ajlm-1946	153	13	.	.	PUNCT
ajlm-1946	154	1	newborn	newborn	ADJ
ajlm-1946	154	2	screening	screening	NOUN
ajlm-1946	154	3	programmes	programme	NOUN
ajlm-1946	154	4	newborn	newborn	ADJ
ajlm-1946	154	5	screening	screening	NOUN
ajlm-1946	154	6	programmes	programme	NOUN
ajlm-1946	154	7	are	be	AUX
ajlm-1946	154	8	useful	useful	ADJ
ajlm-1946	154	9	for	for	ADP
ajlm-1946	154	10	the	the	DET
ajlm-1946	154	11	early	early	ADJ
ajlm-1946	154	12	detection	detection	NOUN
ajlm-1946	154	13	of	of	ADP
ajlm-1946	154	14	conditions	condition	NOUN
ajlm-1946	154	15	with	with	ADP
ajlm-1946	154	16	a	a	DET
ajlm-1946	154	17	presumptive	presumptive	ADJ
ajlm-1946	154	18	period	period	NOUN
ajlm-1946	154	19	during	during	ADP
ajlm-1946	154	20	which	which	PRON
ajlm-1946	154	21	treatment	treatment	NOUN
ajlm-1946	154	22	can	can	AUX
ajlm-1946	154	23	dramatically	dramatically	ADV
ajlm-1946	154	24	improve	improve	VERB
ajlm-1946	154	25	the	the	DET
ajlm-1946	154	26	outcome	outcome	NOUN
ajlm-1946	154	27	.	.	PUNCT
ajlm-1946	155	1	these	these	DET
ajlm-1946	155	2	programmes	programme	NOUN
ajlm-1946	155	3	are	be	AUX
ajlm-1946	155	4	especially	especially	ADV
ajlm-1946	155	5	useful	useful	ADJ
ajlm-1946	155	6	in	in	ADP
ajlm-1946	155	7	resource	resource	NOUN
ajlm-1946	155	8	-	-	PUNCT
ajlm-1946	155	9	poor	poor	ADJ
ajlm-1946	155	10	countries	country	NOUN
ajlm-1946	155	11	where	where	SCONJ
ajlm-1946	155	12	facilities	facility	NOUN
ajlm-1946	155	13	for	for	ADP
ajlm-1946	155	14	managing	manage	VERB
ajlm-1946	155	15	ensuing	ensue	VERB
ajlm-1946	155	16	complications	complication	NOUN
ajlm-1946	155	17	are	be	AUX
ajlm-1946	155	18	unavailable	unavailable	ADJ
ajlm-1946	155	19	in	in	ADP
ajlm-1946	155	20	delayed	delay	VERB
ajlm-1946	155	21	cases	case	NOUN
ajlm-1946	155	22	.	.	PUNCT
ajlm-1946	156	1	while	while	SCONJ
ajlm-1946	156	2	screening	screen	VERB
ajlm-1946	156	3	programmes	programme	NOUN
ajlm-1946	156	4	are	be	AUX
ajlm-1946	156	5	available	available	ADJ
ajlm-1946	156	6	in	in	ADP
ajlm-1946	156	7	many	many	ADJ
ajlm-1946	156	8	developed	develop	VERB
ajlm-1946	156	9	countries	country	NOUN
ajlm-1946	156	10	,	,	PUNCT
ajlm-1946	156	11	they	they	PRON
ajlm-1946	156	12	are	be	AUX
ajlm-1946	156	13	not	not	PART
ajlm-1946	156	14	available	available	ADJ
ajlm-1946	156	15	in	in	ADP
ajlm-1946	156	16	many	many	ADJ
ajlm-1946	156	17	developing	develop	VERB
ajlm-1946	156	18	countries	country	NOUN
ajlm-1946	156	19	,	,	PUNCT
ajlm-1946	156	20	and	and	CCONJ
ajlm-1946	156	21	those	those	PRON
ajlm-1946	156	22	that	that	PRON
ajlm-1946	156	23	were	be	AUX
ajlm-1946	156	24	previously	previously	ADV
ajlm-1946	156	25	available	available	ADJ
ajlm-1946	156	26	have	have	AUX
ajlm-1946	156	27	degenerated	degenerate	VERB
ajlm-1946	156	28	.	.	PUNCT
ajlm-1946	157	1	the	the	DET
ajlm-1946	157	2	assumption	assumption	NOUN
ajlm-1946	157	3	that	that	SCONJ
ajlm-1946	157	4	the	the	DET
ajlm-1946	157	5	observed	observed	ADJ
ajlm-1946	157	6	degeneration	degeneration	NOUN
ajlm-1946	157	7	is	be	AUX
ajlm-1946	157	8	due	due	ADJ
ajlm-1946	157	9	to	to	ADP
ajlm-1946	157	10	a	a	DET
ajlm-1946	157	11	lack	lack	NOUN
ajlm-1946	157	12	of	of	ADP
ajlm-1946	157	13	advanced	advanced	ADJ
ajlm-1946	157	14	scientific	scientific	ADJ
ajlm-1946	157	15	equipment	equipment	NOUN
ajlm-1946	157	16	required	require	VERB
ajlm-1946	157	17	for	for	ADP
ajlm-1946	157	18	investigation	investigation	NOUN
ajlm-1946	157	19	is	be	AUX
ajlm-1946	157	20	false	false	ADJ
ajlm-1946	157	21	as	as	SCONJ
ajlm-1946	157	22	many	many	ADJ
ajlm-1946	157	23	iems	iem	NOUN
ajlm-1946	157	24	can	can	AUX
ajlm-1946	157	25	be	be	AUX
ajlm-1946	157	26	detected	detect	VERB
ajlm-1946	157	27	using	use	VERB
ajlm-1946	157	28	basic	basic	ADJ
ajlm-1946	157	29	clinical	clinical	ADJ
ajlm-1946	157	30	chemistry	chemistry	NOUN
ajlm-1946	157	31	laboratory	laboratory	NOUN
ajlm-1946	157	32	facilities	facility	NOUN
ajlm-1946	157	33	;	;	PUNCT
ajlm-1946	157	34	this	this	PRON
ajlm-1946	157	35	has	have	AUX
ajlm-1946	157	36	been	be	AUX
ajlm-1946	157	37	demonstrated	demonstrate	VERB
ajlm-1946	157	38	in	in	ADP
ajlm-1946	157	39	this	this	DET
ajlm-1946	157	40	brief	brief	ADJ
ajlm-1946	157	41	article	article	NOUN
ajlm-1946	157	42	and	and	CCONJ
ajlm-1946	157	43	supported	support	VERB
ajlm-1946	157	44	by	by	ADP
ajlm-1946	157	45	brown	brown	NOUN
ajlm-1946	157	46	and	and	CCONJ
ajlm-1946	157	47	lo14	lo14	PROPN
ajlm-1946	157	48	and	and	CCONJ
ajlm-1946	157	49	,	,	PUNCT
ajlm-1946	157	50	more	more	ADV
ajlm-1946	157	51	recently	recently	ADV
ajlm-1946	157	52	,	,	PUNCT
ajlm-1946	157	53	civallero	civallero	PROPN
ajlm-1946	157	54	,	,	PUNCT
ajlm-1946	157	55	de	de	PROPN
ajlm-1946	157	56	kremer	kremer	PROPN
ajlm-1946	157	57	and	and	CCONJ
ajlm-1946	157	58	giugliani.11	giugliani.11	PROPN
ajlm-1946	157	59	even	even	ADV
ajlm-1946	157	60	in	in	ADP
ajlm-1946	157	61	the	the	DET
ajlm-1946	157	62	absence	absence	NOUN
ajlm-1946	157	63	of	of	ADP
ajlm-1946	157	64	tandem	tandem	PROPN
ajlm-1946	157	65	mass	mass	PROPN
ajlm-1946	157	66	spectrophotometry	spectrophotometry	NOUN
ajlm-1946	157	67	in	in	ADP
ajlm-1946	157	68	these	these	DET
ajlm-1946	157	69	countries	country	NOUN
ajlm-1946	157	70	,	,	PUNCT
ajlm-1946	157	71	basic	basic	ADJ
ajlm-1946	157	72	laboratory	laboratory	NOUN
ajlm-1946	157	73	investigations	investigation	NOUN
ajlm-1946	157	74	can	can	AUX
ajlm-1946	157	75	accomplish	accomplish	VERB
ajlm-1946	157	76	a	a	DET
ajlm-1946	157	77	great	great	ADJ
ajlm-1946	157	78	deal	deal	NOUN
ajlm-1946	157	79	.	.	PUNCT
ajlm-1946	158	1	inherited	inherit	VERB
ajlm-1946	158	2	metabolic	metabolic	NOUN
ajlm-1946	158	3	disorders	disorder	NOUN
ajlm-1946	158	4	such	such	ADJ
ajlm-1946	158	5	as	as	ADP
ajlm-1946	158	6	congenital	congenital	ADJ
ajlm-1946	158	7	hypothyroidism	hypothyroidism	NOUN
ajlm-1946	158	8	(	(	PUNCT
ajlm-1946	158	9	cretinism	cretinism	NOUN
ajlm-1946	158	10	)	)	PUNCT
ajlm-1946	158	11	,	,	PUNCT
ajlm-1946	158	12	phenylketonuria	phenylketonuria	NOUN
ajlm-1946	158	13	,	,	PUNCT
ajlm-1946	158	14	and	and	CCONJ
ajlm-1946	158	15	cystic	cystic	ADJ
ajlm-1946	158	16	fibrosis	fibrosis	NOUN
ajlm-1946	158	17	are	be	AUX
ajlm-1946	158	18	commonly	commonly	ADV
ajlm-1946	158	19	screened	screen	VERB
ajlm-1946	158	20	for	for	ADP
ajlm-1946	158	21	in	in	ADP
ajlm-1946	158	22	high	high	ADJ
ajlm-1946	158	23	-	-	PUNCT
ajlm-1946	158	24	income	income	NOUN
ajlm-1946	158	25	countries	country	NOUN
ajlm-1946	158	26	like	like	ADP
ajlm-1946	158	27	the	the	DET
ajlm-1946	158	28	united	united	ADJ
ajlm-1946	158	29	kingdom	kingdom	PROPN
ajlm-1946	158	30	.	.	PUNCT
ajlm-1946	159	1	in	in	ADP
ajlm-1946	159	2	developing	develop	VERB
ajlm-1946	159	3	countries	country	NOUN
ajlm-1946	159	4	,	,	PUNCT
ajlm-1946	159	5	these	these	DET
ajlm-1946	159	6	disorders	disorder	NOUN
ajlm-1946	159	7	,	,	PUNCT
ajlm-1946	159	8	as	as	ADV
ajlm-1946	159	9	well	well	ADV
ajlm-1946	159	10	as	as	ADP
ajlm-1946	159	11	others	other	NOUN
ajlm-1946	159	12	such	such	ADJ
ajlm-1946	159	13	as	as	ADP
ajlm-1946	159	14	maple	maple	NOUN
ajlm-1946	159	15	syrup	syrup	NOUN
ajlm-1946	159	16	urine	urine	NOUN
ajlm-1946	159	17	disease	disease	NOUN
ajlm-1946	159	18	,	,	PUNCT
ajlm-1946	159	19	galactosaemia	galactosaemia	NOUN
ajlm-1946	159	20	,	,	PUNCT
ajlm-1946	159	21	alpha-1	alpha-1	NUM
ajlm-1946	159	22	-	-	PUNCT
ajlm-1946	159	23	antitrypsin	antitrypsin	NOUN
ajlm-1946	159	24	deficiency	deficiency	NOUN
ajlm-1946	159	25	,	,	PUNCT
ajlm-1946	159	26	ucds	ucds	NOUN
ajlm-1946	159	27	,	,	PUNCT
ajlm-1946	159	28	and	and	CCONJ
ajlm-1946	159	29	l	l	NOUN
ajlm-1946	159	30	-	-	NOUN
ajlm-1946	159	31	n	n	PRON
ajlm-1946	159	32	syndrome	syndrome	NOUN
ajlm-1946	159	33	,	,	PUNCT
ajlm-1946	159	34	can	can	AUX
ajlm-1946	159	35	also	also	ADV
ajlm-1946	159	36	routinely	routinely	ADV
ajlm-1946	159	37	be	be	AUX
ajlm-1946	159	38	investigated	investigate	VERB
ajlm-1946	159	39	using	use	VERB
ajlm-1946	159	40	basic	basic	ADJ
ajlm-1946	159	41	laboratory	laboratory	NOUN
ajlm-1946	159	42	facilities	facility	NOUN
ajlm-1946	159	43	.	.	PUNCT
ajlm-1946	160	1	for	for	ADP
ajlm-1946	160	2	early	early	ADJ
ajlm-1946	160	3	diagnosis	diagnosis	NOUN
ajlm-1946	160	4	and	and	CCONJ
ajlm-1946	160	5	to	to	PART
ajlm-1946	160	6	avoid	avoid	VERB
ajlm-1946	160	7	the	the	DET
ajlm-1946	160	8	serious	serious	ADJ
ajlm-1946	160	9	and	and	CCONJ
ajlm-1946	160	10	irreversible	irreversible	ADJ
ajlm-1946	160	11	consequences	consequence	NOUN
ajlm-1946	160	12	of	of	ADP
ajlm-1946	160	13	iem	iem	PROPN
ajlm-1946	160	14	,	,	PUNCT
ajlm-1946	160	15	close	close	ADJ
ajlm-1946	160	16	collaboration	collaboration	NOUN
ajlm-1946	160	17	between	between	ADP
ajlm-1946	160	18	clinics	clinic	NOUN
ajlm-1946	160	19	and	and	CCONJ
ajlm-1946	160	20	metabolic	metabolic	NOUN
ajlm-1946	160	21	laboratories	laboratory	NOUN
ajlm-1946	160	22	,	,	PUNCT
ajlm-1946	160	23	or	or	CCONJ
ajlm-1946	160	24	just	just	ADV
ajlm-1946	160	25	clinical	clinical	ADJ
ajlm-1946	160	26	laboratories	laboratory	NOUN
ajlm-1946	160	27	,	,	PUNCT
ajlm-1946	160	28	is	be	AUX
ajlm-1946	160	29	critical	critical	ADJ
ajlm-1946	160	30	.	.	PUNCT
ajlm-1946	161	1	a	a	DET
ajlm-1946	161	2	structured	structured	ADJ
ajlm-1946	161	3	approach	approach	NOUN
ajlm-1946	161	4	should	should	AUX
ajlm-1946	161	5	be	be	AUX
ajlm-1946	161	6	in	in	ADP
ajlm-1946	161	7	place	place	NOUN
ajlm-1946	161	8	and	and	CCONJ
ajlm-1946	161	9	may	may	AUX
ajlm-1946	161	10	include	include	VERB
ajlm-1946	161	11	targeted	target	VERB
ajlm-1946	161	12	laboratory	laboratory	NOUN
ajlm-1946	161	13	investigation	investigation	NOUN
ajlm-1946	161	14	and	and	CCONJ
ajlm-1946	161	15	a	a	DET
ajlm-1946	161	16	comprehensive	comprehensive	ADJ
ajlm-1946	161	17	patient	patient	NOUN
ajlm-1946	161	18	examination	examination	NOUN
ajlm-1946	161	19	to	to	PART
ajlm-1946	161	20	assess	assess	VERB
ajlm-1946	161	21	drug	drug	NOUN
ajlm-1946	161	22	use	use	NOUN
ajlm-1946	161	23	,	,	PUNCT
ajlm-1946	161	24	feeding	feed	VERB
ajlm-1946	161	25	history	history	NOUN
ajlm-1946	161	26	,	,	PUNCT
ajlm-1946	161	27	transfusion	transfusion	NOUN
ajlm-1946	161	28	history	history	NOUN
ajlm-1946	161	29	,	,	PUNCT
ajlm-1946	161	30	and	and	CCONJ
ajlm-1946	161	31	family	family	NOUN
ajlm-1946	161	32	medical	medical	ADJ
ajlm-1946	161	33	history	history	NOUN
ajlm-1946	161	34	.	.	PUNCT
ajlm-1946	162	1	at	at	ADP
ajlm-1946	162	2	the	the	DET
ajlm-1946	162	3	minimum	minimum	NOUN
ajlm-1946	162	4	,	,	PUNCT
ajlm-1946	162	5	an	an	DET
ajlm-1946	162	6	iem	iem	ADJ
ajlm-1946	162	7	team	team	NOUN
ajlm-1946	162	8	consisting	consist	VERB
ajlm-1946	162	9	of	of	ADP
ajlm-1946	162	10	clinicians	clinician	NOUN
ajlm-1946	162	11	(	(	PUNCT
ajlm-1946	162	12	paediatricians	paediatrician	NOUN
ajlm-1946	162	13	)	)	PUNCT
ajlm-1946	162	14	,	,	PUNCT
ajlm-1946	162	15	a	a	DET
ajlm-1946	162	16	clinical	clinical	ADJ
ajlm-1946	162	17	chemist	chemist	NOUN
ajlm-1946	162	18	or	or	CCONJ
ajlm-1946	162	19	laboratory	laboratory	NOUN
ajlm-1946	162	20	scientist	scientist	NOUN
ajlm-1946	162	21	,	,	PUNCT
ajlm-1946	162	22	and	and	CCONJ
ajlm-1946	162	23	a	a	DET
ajlm-1946	162	24	dietician	dietician	NOUN
ajlm-1946	162	25	must	must	AUX
ajlm-1946	162	26	be	be	AUX
ajlm-1946	162	27	available	available	ADJ
ajlm-1946	162	28	.	.	PUNCT
ajlm-1946	163	1	interpretation	interpretation	NOUN
ajlm-1946	163	2	of	of	ADP
ajlm-1946	163	3	findings	finding	NOUN
ajlm-1946	163	4	should	should	AUX
ajlm-1946	163	5	take	take	VERB
ajlm-1946	163	6	a	a	DET
ajlm-1946	163	7	multidisciplinary	multidisciplinary	ADJ
ajlm-1946	163	8	approach	approach	NOUN
ajlm-1946	163	9	as	as	SCONJ
ajlm-1946	163	10	this	this	PRON
ajlm-1946	163	11	is	be	AUX
ajlm-1946	163	12	one	one	NUM
ajlm-1946	163	13	area	area	NOUN
ajlm-1946	163	14	where	where	SCONJ
ajlm-1946	163	15	clinicians	clinician	NOUN
ajlm-1946	163	16	require	require	VERB
ajlm-1946	163	17	a	a	DET
ajlm-1946	163	18	great	great	ADJ
ajlm-1946	163	19	deal	deal	NOUN
ajlm-1946	163	20	of	of	ADP
ajlm-1946	163	21	guidance	guidance	NOUN
ajlm-1946	163	22	from	from	ADP
ajlm-1946	163	23	laboratory	laboratory	NOUN
ajlm-1946	163	24	specialists	specialist	NOUN
ajlm-1946	163	25	.	.	PUNCT
ajlm-1946	164	1	many	many	ADJ
ajlm-1946	164	2	physicians	physician	NOUN
ajlm-1946	164	3	who	who	PRON
ajlm-1946	164	4	request	request	VERB
ajlm-1946	164	5	laboratory	laboratory	NOUN
ajlm-1946	164	6	tests	test	NOUN
ajlm-1946	164	7	are	be	AUX
ajlm-1946	164	8	unfamiliar	unfamiliar	ADJ
ajlm-1946	164	9	with	with	ADP
ajlm-1946	164	10	the	the	DET
ajlm-1946	164	11	metabolic	metabolic	NOUN
ajlm-1946	164	12	derangements	derangement	NOUN
ajlm-1946	164	13	associated	associate	VERB
ajlm-1946	164	14	with	with	ADP
ajlm-1946	164	15	various	various	ADJ
ajlm-1946	164	16	iems	iem	NOUN
ajlm-1946	164	17	.	.	PUNCT
ajlm-1946	165	1	brown	brown	ADJ
ajlm-1946	165	2	and	and	CCONJ
ajlm-1946	165	3	lo14	lo14	PROPN
ajlm-1946	165	4	propose	propose	VERB
ajlm-1946	165	5	that	that	SCONJ
ajlm-1946	165	6	metabolic	metabolic	NOUN
ajlm-1946	165	7	investigation	investigation	NOUN
ajlm-1946	165	8	reports	report	NOUN
ajlm-1946	165	9	should	should	AUX
ajlm-1946	165	10	include	include	VERB
ajlm-1946	165	11	age	age	NOUN
ajlm-1946	165	12	-	-	PUNCT
ajlm-1946	165	13	related	relate	VERB
ajlm-1946	165	14	reference	reference	NOUN
ajlm-1946	165	15	intervals	interval	NOUN
ajlm-1946	165	16	for	for	ADP
ajlm-1946	165	17	quantitative	quantitative	ADJ
ajlm-1946	165	18	results	result	NOUN
ajlm-1946	165	19	.	.	PUNCT
ajlm-1946	166	1	with	with	ADP
ajlm-1946	166	2	a	a	DET
ajlm-1946	166	3	differential	differential	ADJ
ajlm-1946	166	4	diagnosis	diagnosis	NOUN
ajlm-1946	166	5	derived	derive	VERB
ajlm-1946	166	6	from	from	ADP
ajlm-1946	166	7	relevant	relevant	ADJ
ajlm-1946	166	8	abnormal	abnormal	ADJ
ajlm-1946	166	9	and/or	and/or	CCONJ
ajlm-1946	166	10	normal	normal	ADJ
ajlm-1946	166	11	data	datum	NOUN
ajlm-1946	166	12	,	,	PUNCT
ajlm-1946	166	13	recommendations	recommendation	NOUN
ajlm-1946	166	14	for	for	ADP
ajlm-1946	166	15	further	further	ADJ
ajlm-1946	166	16	specialist	specialist	ADJ
ajlm-1946	166	17	investigations	investigation	NOUN
ajlm-1946	166	18	,	,	PUNCT
ajlm-1946	166	19	and	and	CCONJ
ajlm-1946	166	20	sufficient	sufficient	ADJ
ajlm-1946	166	21	contact	contact	NOUN
ajlm-1946	166	22	information	information	NOUN
ajlm-1946	166	23	for	for	ADP
ajlm-1946	166	24	such	such	ADJ
ajlm-1946	166	25	institutions	institution	NOUN
ajlm-1946	166	26	,	,	PUNCT
ajlm-1946	166	27	there	there	PRON
ajlm-1946	166	28	should	should	AUX
ajlm-1946	166	29	be	be	AUX
ajlm-1946	166	30	enough	enough	ADJ
ajlm-1946	166	31	collaboration	collaboration	NOUN
ajlm-1946	166	32	for	for	ADP
ajlm-1946	166	33	clinicians	clinician	NOUN
ajlm-1946	166	34	to	to	PART
ajlm-1946	166	35	feel	feel	VERB
ajlm-1946	166	36	free	free	ADJ
ajlm-1946	166	37	to	to	PART
ajlm-1946	166	38	contact	contact	VERB
ajlm-1946	166	39	the	the	DET
ajlm-1946	166	40	laboratory	laboratory	NOUN
ajlm-1946	166	41	if	if	SCONJ
ajlm-1946	166	42	questions	question	NOUN
ajlm-1946	166	43	arise	arise	VERB
ajlm-1946	166	44	.	.	PUNCT
ajlm-1946	167	1	laboratory	laboratory	NOUN
ajlm-1946	167	2	reports	report	NOUN
ajlm-1946	167	3	are	be	AUX
ajlm-1946	167	4	best	well	ADV
ajlm-1946	167	5	interpreted	interpret	VERB
ajlm-1946	167	6	when	when	SCONJ
ajlm-1946	167	7	clinical	clinical	ADJ
ajlm-1946	167	8	and	and	CCONJ
ajlm-1946	167	9	relevant	relevant	ADJ
ajlm-1946	167	10	laboratory	laboratory	NOUN
ajlm-1946	167	11	information	information	NOUN
ajlm-1946	167	12	are	be	AUX
ajlm-1946	167	13	provided	provide	VERB
ajlm-1946	167	14	along	along	ADP
ajlm-1946	167	15	with	with	ADP
ajlm-1946	167	16	the	the	DET
ajlm-1946	167	17	test	test	NOUN
ajlm-1946	167	18	requisition	requisition	NOUN
ajlm-1946	167	19	,	,	PUNCT
ajlm-1946	167	20	as	as	SCONJ
ajlm-1946	167	21	is	be	AUX
ajlm-1946	167	22	well	well	ADV
ajlm-1946	167	23	-	-	PUNCT
ajlm-1946	167	24	known	know	VERB
ajlm-1946	167	25	in	in	ADP
ajlm-1946	167	26	pathology	pathology	NOUN
ajlm-1946	167	27	and	and	CCONJ
ajlm-1946	167	28	laboratory	laboratory	NOUN
ajlm-1946	167	29	medicine	medicine	NOUN
ajlm-1946	167	30	.	.	PUNCT
ajlm-1946	168	1	results	result	NOUN
ajlm-1946	168	2	pointing	point	VERB
ajlm-1946	168	3	to	to	ADP
ajlm-1946	168	4	multiple	multiple	ADJ
ajlm-1946	168	5	iems	iem	NOUN
ajlm-1946	168	6	should	should	AUX
ajlm-1946	168	7	be	be	AUX
ajlm-1946	168	8	correlated	correlate	VERB
ajlm-1946	168	9	with	with	ADP
ajlm-1946	168	10	the	the	DET
ajlm-1946	168	11	patient	patient	NOUN
ajlm-1946	168	12	’s	’s	PART
ajlm-1946	168	13	clinical	clinical	ADJ
ajlm-1946	168	14	and	and	CCONJ
ajlm-1946	168	15	laboratory	laboratory	NOUN
ajlm-1946	168	16	data	datum	NOUN
ajlm-1946	168	17	to	to	PART
ajlm-1946	168	18	narrow	narrow	VERB
ajlm-1946	168	19	the	the	DET
ajlm-1946	168	20	differential	differential	ADJ
ajlm-1946	168	21	diagnosis	diagnosis	NOUN
ajlm-1946	168	22	before	before	ADP
ajlm-1946	168	23	further	further	ADJ
ajlm-1946	168	24	investigation.14,30	investigation.14,30	NOUN
ajlm-1946	168	25	it	it	PRON
ajlm-1946	168	26	is	be	AUX
ajlm-1946	168	27	recommended	recommend	VERB
ajlm-1946	168	28	to	to	PART
ajlm-1946	168	29	conduct	conduct	VERB
ajlm-1946	168	30	basic	basic	ADJ
ajlm-1946	168	31	investigations	investigation	NOUN
ajlm-1946	168	32	that	that	PRON
ajlm-1946	168	33	are	be	AUX
ajlm-1946	168	34	useful	useful	ADJ
ajlm-1946	168	35	in	in	ADP
ajlm-1946	168	36	the	the	DET
ajlm-1946	168	37	diagnosis	diagnosis	NOUN
ajlm-1946	168	38	of	of	ADP
ajlm-1946	168	39	iems	iem	NOUN
ajlm-1946	168	40	as	as	SCONJ
ajlm-1946	168	41	these	these	PRON
ajlm-1946	168	42	are	be	AUX
ajlm-1946	168	43	beneficial	beneficial	ADJ
ajlm-1946	168	44	to	to	ADP
ajlm-1946	168	45	the	the	DET
ajlm-1946	168	46	community	community	NOUN
ajlm-1946	168	47	(	(	PUNCT
ajlm-1946	168	48	table	table	NOUN
ajlm-1946	168	49	3).31	3).31	NUM
ajlm-1946	168	50	table	table	NOUN
ajlm-1946	169	1	3	3	NUM
ajlm-1946	169	2	:	:	PUNCT
ajlm-1946	169	3	 	 	SPACE
ajlm-1946	169	4	basic	basic	ADJ
ajlm-1946	169	5	investigations	investigation	NOUN
ajlm-1946	169	6	useful	useful	ADJ
ajlm-1946	169	7	in	in	ADP
ajlm-1946	169	8	the	the	DET
ajlm-1946	169	9	diagnosis	diagnosis	NOUN
ajlm-1946	169	10	of	of	ADP
ajlm-1946	169	11	inborn	inborn	ADJ
ajlm-1946	169	12	errors	error	NOUN
ajlm-1946	169	13	of	of	ADP
ajlm-1946	169	14	metabolism	metabolism	NOUN
ajlm-1946	169	15	.	.	PUNCT
ajlm-1946	170	1	conclusion	conclusion	NOUN
ajlm-1946	170	2	although	although	SCONJ
ajlm-1946	170	3	the	the	DET
ajlm-1946	170	4	individual	individual	ADJ
ajlm-1946	170	5	types	type	NOUN
ajlm-1946	170	6	of	of	ADP
ajlm-1946	170	7	iems	iem	NOUN
ajlm-1946	170	8	are	be	AUX
ajlm-1946	170	9	rare	rare	ADJ
ajlm-1946	170	10	,	,	PUNCT
ajlm-1946	170	11	this	this	DET
ajlm-1946	170	12	category	category	NOUN
ajlm-1946	170	13	of	of	ADP
ajlm-1946	170	14	diseases	disease	NOUN
ajlm-1946	170	15	is	be	AUX
ajlm-1946	170	16	common	common	ADJ
ajlm-1946	170	17	and	and	CCONJ
ajlm-1946	170	18	often	often	ADV
ajlm-1946	170	19	severe	severe	ADJ
ajlm-1946	170	20	.	.	PUNCT
ajlm-1946	171	1	because	because	SCONJ
ajlm-1946	171	2	severe	severe	ADJ
ajlm-1946	171	3	morbidity	morbidity	NOUN
ajlm-1946	171	4	and/or	and/or	CCONJ
ajlm-1946	171	5	mortality	mortality	NOUN
ajlm-1946	171	6	can	can	AUX
ajlm-1946	171	7	be	be	AUX
ajlm-1946	171	8	avoided	avoid	VERB
ajlm-1946	171	9	in	in	ADP
ajlm-1946	171	10	some	some	DET
ajlm-1946	171	11	forms	form	NOUN
ajlm-1946	171	12	of	of	ADP
ajlm-1946	171	13	iem	iem	PROPN
ajlm-1946	171	14	,	,	PUNCT
ajlm-1946	171	15	it	it	PRON
ajlm-1946	171	16	is	be	AUX
ajlm-1946	171	17	critical	critical	ADJ
ajlm-1946	171	18	to	to	PART
ajlm-1946	171	19	make	make	VERB
ajlm-1946	171	20	accurate	accurate	ADJ
ajlm-1946	171	21	diagnoses	diagnosis	NOUN
ajlm-1946	171	22	early	early	ADV
ajlm-1946	171	23	,	,	PUNCT
ajlm-1946	171	24	especially	especially	ADV
ajlm-1946	171	25	in	in	ADP
ajlm-1946	171	26	developing	develop	VERB
ajlm-1946	171	27	countries	country	NOUN
ajlm-1946	171	28	with	with	ADP
ajlm-1946	171	29	limited	limited	ADJ
ajlm-1946	171	30	complication	complication	NOUN
ajlm-1946	171	31	management	management	NOUN
ajlm-1946	171	32	facilities	facility	NOUN
ajlm-1946	171	33	.	.	PUNCT
ajlm-1946	172	1	though	though	SCONJ
ajlm-1946	172	2	the	the	DET
ajlm-1946	172	3	definitive	definitive	ADJ
ajlm-1946	172	4	diagnosis	diagnosis	NOUN
ajlm-1946	172	5	of	of	ADP
ajlm-1946	172	6	iems	iem	NOUN
ajlm-1946	172	7	may	may	AUX
ajlm-1946	172	8	require	require	VERB
ajlm-1946	172	9	specialised	specialised	ADJ
ajlm-1946	172	10	laboratory	laboratory	NOUN
ajlm-1946	172	11	investigations	investigation	NOUN
ajlm-1946	172	12	and	and	CCONJ
ajlm-1946	172	13	interpretation	interpretation	NOUN
ajlm-1946	172	14	,	,	PUNCT
ajlm-1946	172	15	basic	basic	ADJ
ajlm-1946	172	16	investigations	investigation	NOUN
ajlm-1946	172	17	that	that	PRON
ajlm-1946	172	18	can	can	AUX
ajlm-1946	172	19	be	be	AUX
ajlm-1946	172	20	conducted	conduct	VERB
ajlm-1946	172	21	in	in	ADP
ajlm-1946	172	22	the	the	DET
ajlm-1946	172	23	average	average	ADJ
ajlm-1946	172	24	clinical	clinical	ADJ
ajlm-1946	172	25	chemistry	chemistry	NOUN
ajlm-1946	172	26	laboratory	laboratory	NOUN
ajlm-1946	172	27	in	in	ADP
ajlm-1946	172	28	developing	develop	VERB
ajlm-1946	172	29	countries	country	NOUN
ajlm-1946	172	30	can	can	AUX
ajlm-1946	172	31	provide	provide	VERB
ajlm-1946	172	32	valuable	valuable	ADJ
ajlm-1946	172	33	information	information	NOUN
ajlm-1946	172	34	for	for	ADP
ajlm-1946	172	35	critical	critical	ADJ
ajlm-1946	172	36	and	and	CCONJ
ajlm-1946	172	37	early	early	ADJ
ajlm-1946	172	38	decision	decision	NOUN
ajlm-1946	172	39	making	make	VERB
ajlm-1946	172	40	in	in	ADP
ajlm-1946	172	41	most	most	ADJ
ajlm-1946	172	42	cases	case	NOUN
ajlm-1946	172	43	.	.	PUNCT
ajlm-1946	173	1	referrals	referral	NOUN
ajlm-1946	173	2	to	to	ADP
ajlm-1946	173	3	specialised	specialised	ADJ
ajlm-1946	173	4	centres	centre	NOUN
ajlm-1946	173	5	for	for	ADP
ajlm-1946	173	6	further	further	ADJ
ajlm-1946	173	7	investigation	investigation	NOUN
ajlm-1946	173	8	can	can	AUX
ajlm-1946	173	9	then	then	ADV
ajlm-1946	173	10	be	be	AUX
ajlm-1946	173	11	done	do	VERB
ajlm-1946	173	12	.	.	PUNCT
ajlm-1946	174	1	appropriate	appropriate	ADJ
ajlm-1946	174	2	interpretation	interpretation	NOUN
ajlm-1946	174	3	of	of	ADP
ajlm-1946	174	4	investigation	investigation	NOUN
ajlm-1946	174	5	findings	finding	NOUN
ajlm-1946	174	6	requires	require	VERB
ajlm-1946	174	7	interdisciplinary	interdisciplinary	ADJ
ajlm-1946	174	8	collaboration	collaboration	NOUN
ajlm-1946	174	9	between	between	ADP
ajlm-1946	174	10	clinical	clinical	ADJ
ajlm-1946	174	11	laboratory	laboratory	NOUN
ajlm-1946	174	12	scientists	scientist	NOUN
ajlm-1946	174	13	and	and	CCONJ
ajlm-1946	174	14	clinicians	clinician	NOUN
ajlm-1946	174	15	and	and	CCONJ
ajlm-1946	174	16	is	be	AUX
ajlm-1946	174	17	critical	critical	ADJ
ajlm-1946	174	18	for	for	ADP
ajlm-1946	174	19	the	the	DET
ajlm-1946	174	20	early	early	ADJ
ajlm-1946	174	21	diagnosis	diagnosis	NOUN
ajlm-1946	174	22	of	of	ADP
ajlm-1946	174	23	patients	patient	NOUN
ajlm-1946	174	24	with	with	ADP
ajlm-1946	174	25	iem	iem	PROPN
ajlm-1946	174	26	and	and	CCONJ
ajlm-1946	174	27	improved	improve	VERB
ajlm-1946	174	28	management	management	NOUN
ajlm-1946	174	29	of	of	ADP
ajlm-1946	174	30	complex	complex	ADJ
ajlm-1946	174	31	cases	case	NOUN
ajlm-1946	174	32	.	.	PUNCT
ajlm-1946	175	1	a	a	DET
ajlm-1946	175	2	good	good	ADJ
ajlm-1946	175	3	team	team	NOUN
ajlm-1946	175	4	of	of	ADP
ajlm-1946	175	5	paediatricians	paediatrician	NOUN
ajlm-1946	175	6	,	,	PUNCT
ajlm-1946	175	7	clinical	clinical	ADJ
ajlm-1946	175	8	chemists	chemist	NOUN
ajlm-1946	175	9	(	(	PUNCT
ajlm-1946	175	10	or	or	CCONJ
ajlm-1946	175	11	laboratory	laboratory	NOUN
ajlm-1946	175	12	scientists	scientist	NOUN
ajlm-1946	175	13	)	)	PUNCT
ajlm-1946	175	14	,	,	PUNCT
ajlm-1946	175	15	and	and	CCONJ
ajlm-1946	175	16	a	a	DET
ajlm-1946	175	17	dietician	dietician	NOUN
ajlm-1946	175	18	can	can	AUX
ajlm-1946	175	19	be	be	AUX
ajlm-1946	175	20	extremely	extremely	ADV
ajlm-1946	175	21	useful	useful	ADJ
ajlm-1946	175	22	.	.	PUNCT
ajlm-1946	176	1	it	it	PRON
ajlm-1946	176	2	is	be	AUX
ajlm-1946	176	3	critical	critical	ADJ
ajlm-1946	176	4	to	to	PART
ajlm-1946	176	5	emphasise	emphasise	VERB
ajlm-1946	176	6	that	that	DET
ajlm-1946	176	7	education	education	NOUN
ajlm-1946	176	8	and	and	CCONJ
ajlm-1946	176	9	training	training	NOUN
ajlm-1946	176	10	for	for	ADP
ajlm-1946	176	11	both	both	DET
ajlm-1946	176	12	health	health	NOUN
ajlm-1946	176	13	and	and	CCONJ
ajlm-1946	176	14	non	non	ADJ
ajlm-1946	176	15	-	-	ADJ
ajlm-1946	176	16	health	health	ADJ
ajlm-1946	176	17	professionals	professional	NOUN
ajlm-1946	176	18	are	be	AUX
ajlm-1946	176	19	both	both	PRON
ajlm-1946	176	20	essential	essential	ADJ
ajlm-1946	176	21	and	and	CCONJ
ajlm-1946	176	22	beneficial	beneficial	ADJ
ajlm-1946	176	23	.	.	PUNCT
ajlm-1946	177	1	health	health	NOUN
ajlm-1946	177	2	facilities	facility	NOUN
ajlm-1946	177	3	in	in	ADP
ajlm-1946	177	4	developing	develop	VERB
ajlm-1946	177	5	countries	country	NOUN
ajlm-1946	177	6	need	need	VERB
ajlm-1946	177	7	support	support	NOUN
ajlm-1946	177	8	from	from	ADP
ajlm-1946	177	9	international	international	ADJ
ajlm-1946	177	10	organisations	organisation	NOUN
ajlm-1946	177	11	like	like	ADP
ajlm-1946	177	12	the	the	DET
ajlm-1946	177	13	international	international	PROPN
ajlm-1946	177	14	federation	federation	PROPN
ajlm-1946	177	15	of	of	ADP
ajlm-1946	177	16	clinical	clinical	ADJ
ajlm-1946	177	17	chemistry	chemistry	NOUN
ajlm-1946	177	18	to	to	PART
ajlm-1946	177	19	improve	improve	VERB
ajlm-1946	177	20	current	current	ADJ
ajlm-1946	177	21	diagnostic	diagnostic	ADJ
ajlm-1946	177	22	capacity	capacity	NOUN
ajlm-1946	177	23	.	.	PUNCT
ajlm-1946	178	1	acknowledgements	acknowledgement	NOUN
ajlm-1946	178	2	competing	compete	VERB
ajlm-1946	178	3	interests	interest	NOUN
ajlm-1946	178	4	the	the	DET
ajlm-1946	178	5	authors	author	NOUN
ajlm-1946	178	6	declare	declare	VERB
ajlm-1946	178	7	that	that	SCONJ
ajlm-1946	178	8	they	they	PRON
ajlm-1946	178	9	have	have	VERB
ajlm-1946	178	10	no	no	DET
ajlm-1946	178	11	financial	financial	ADJ
ajlm-1946	178	12	or	or	CCONJ
ajlm-1946	178	13	personal	personal	ADJ
ajlm-1946	178	14	relationships	relationship	NOUN
ajlm-1946	178	15	that	that	PRON
ajlm-1946	178	16	may	may	AUX
ajlm-1946	178	17	have	have	AUX
ajlm-1946	178	18	inappropriately	inappropriately	ADV
ajlm-1946	178	19	influenced	influence	VERB
ajlm-1946	178	20	them	they	PRON
ajlm-1946	178	21	in	in	ADP
ajlm-1946	178	22	writing	write	VERB
ajlm-1946	178	23	this	this	DET
ajlm-1946	178	24	article	article	NOUN
ajlm-1946	178	25	.	.	PUNCT
ajlm-1946	179	1	authors	author	NOUN
ajlm-1946	179	2	’	’	PART
ajlm-1946	179	3	contributions	contribution	NOUN
ajlm-1946	179	4	j.i.a	j.i.a	ADV
ajlm-1946	179	5	.	.	PUNCT
ajlm-1946	179	6	,	,	PUNCT
ajlm-1946	179	7	b.e.o	b.e.o	PROPN
ajlm-1946	179	8	.	.	PUNCT
ajlm-1946	179	9	and	and	CCONJ
ajlm-1946	179	10	g.o.a	g.o.a	PROPN
ajlm-1946	179	11	.	.	PUNCT
ajlm-1946	179	12	contributed	contribute	VERB
ajlm-1946	179	13	equally	equally	ADV
ajlm-1946	179	14	to	to	ADP
ajlm-1946	179	15	the	the	DET
ajlm-1946	179	16	conceptualisation	conceptualisation	NOUN
ajlm-1946	179	17	,	,	PUNCT
ajlm-1946	179	18	review	review	NOUN
ajlm-1946	179	19	and	and	CCONJ
ajlm-1946	179	20	final	final	ADJ
ajlm-1946	179	21	approval	approval	NOUN
ajlm-1946	179	22	of	of	ADP
ajlm-1946	179	23	the	the	DET
ajlm-1946	179	24	manuscript	manuscript	NOUN
ajlm-1946	179	25	.	.	PUNCT
ajlm-1946	180	1	ethical	ethical	ADJ
ajlm-1946	180	2	considerations	consideration	NOUN
ajlm-1946	180	3	this	this	DET
ajlm-1946	180	4	article	article	NOUN
ajlm-1946	180	5	followed	follow	VERB
ajlm-1946	180	6	all	all	DET
ajlm-1946	180	7	ethical	ethical	ADJ
ajlm-1946	180	8	standards	standard	NOUN
ajlm-1946	180	9	for	for	ADP
ajlm-1946	180	10	research	research	NOUN
ajlm-1946	180	11	without	without	ADP
ajlm-1946	180	12	direct	direct	ADJ
ajlm-1946	180	13	contact	contact	NOUN
ajlm-1946	180	14	with	with	ADP
ajlm-1946	180	15	human	human	ADJ
ajlm-1946	180	16	or	or	CCONJ
ajlm-1946	180	17	animal	animal	NOUN
ajlm-1946	180	18	subjects	subject	NOUN
ajlm-1946	180	19	.	.	PUNCT
ajlm-1946	181	1	sources	source	NOUN
ajlm-1946	181	2	of	of	ADP
ajlm-1946	181	3	support	support	NOUN
ajlm-1946	181	4	this	this	DET
ajlm-1946	181	5	research	research	NOUN
ajlm-1946	181	6	received	receive	VERB
ajlm-1946	181	7	no	no	DET
ajlm-1946	181	8	specific	specific	ADJ
ajlm-1946	181	9	grant	grant	NOUN
ajlm-1946	181	10	from	from	ADP
ajlm-1946	181	11	any	any	DET
ajlm-1946	181	12	funding	funding	NOUN
ajlm-1946	181	13	agency	agency	NOUN
ajlm-1946	181	14	in	in	ADP
ajlm-1946	181	15	the	the	DET
ajlm-1946	181	16	public	public	ADJ
ajlm-1946	181	17	,	,	PUNCT
ajlm-1946	181	18	commercial	commercial	ADJ
ajlm-1946	181	19	,	,	PUNCT
ajlm-1946	181	20	or	or	CCONJ
ajlm-1946	181	21	not	not	PART
ajlm-1946	181	22	-	-	PUNCT
ajlm-1946	181	23	for	for	ADP
ajlm-1946	181	24	-	-	PUNCT
ajlm-1946	181	25	profit	profit	NOUN
ajlm-1946	181	26	sectors	sector	NOUN
ajlm-1946	181	27	.	.	PUNCT
ajlm-1946	182	1	data	datum	NOUN
ajlm-1946	182	2	availability	availability	NOUN
ajlm-1946	182	3	data	datum	NOUN
ajlm-1946	182	4	sharing	sharing	NOUN
ajlm-1946	182	5	does	do	AUX
ajlm-1946	182	6	not	not	PART
ajlm-1946	182	7	apply	apply	VERB
ajlm-1946	182	8	to	to	ADP
ajlm-1946	182	9	this	this	DET
ajlm-1946	182	10	article	article	NOUN
ajlm-1946	182	11	as	as	SCONJ
ajlm-1946	182	12	no	no	DET
ajlm-1946	182	13	new	new	ADJ
ajlm-1946	182	14	data	datum	NOUN
ajlm-1946	182	15	were	be	AUX
ajlm-1946	182	16	created	create	VERB
ajlm-1946	182	17	or	or	CCONJ
ajlm-1946	182	18	analysed	analyse	VERB
ajlm-1946	182	19	in	in	ADP
ajlm-1946	182	20	this	this	DET
ajlm-1946	182	21	study	study	NOUN
ajlm-1946	182	22	.	.	PUNCT
ajlm-1946	183	1	disclaimer	disclaimer	VERB
ajlm-1946	183	2	the	the	DET
ajlm-1946	183	3	views	view	NOUN
ajlm-1946	183	4	and	and	CCONJ
ajlm-1946	183	5	opinions	opinion	NOUN
ajlm-1946	183	6	expressed	express	VERB
ajlm-1946	183	7	in	in	ADP
ajlm-1946	183	8	this	this	DET
ajlm-1946	183	9	manuscript	manuscript	NOUN
ajlm-1946	183	10	are	be	AUX
ajlm-1946	183	11	those	those	PRON
ajlm-1946	183	12	of	of	ADP
ajlm-1946	183	13	the	the	DET
ajlm-1946	183	14	authors	author	NOUN
ajlm-1946	183	15	and	and	CCONJ
ajlm-1946	183	16	do	do	AUX
ajlm-1946	183	17	not	not	PART
ajlm-1946	183	18	reflect	reflect	VERB
ajlm-1946	183	19	the	the	DET
ajlm-1946	183	20	official	official	ADJ
ajlm-1946	183	21	policy	policy	NOUN
ajlm-1946	183	22	or	or	CCONJ
ajlm-1946	183	23	position	position	NOUN
ajlm-1946	183	24	of	of	ADP
ajlm-1946	183	25	any	any	DET
ajlm-1946	183	26	affiliated	affiliated	ADJ
ajlm-1946	183	27	agency	agency	NOUN
ajlm-1946	183	28	of	of	ADP
ajlm-1946	183	29	the	the	DET
ajlm-1946	183	30	authors	author	NOUN
ajlm-1946	183	31	.	.	PUNCT
ajlm-1946	184	1	references	reference	NOUN
ajlm-1946	184	2	garrod	garrod	PROPN
ajlm-1946	184	3	ae	ae	PROPN
ajlm-1946	184	4	.	.	PUNCT
ajlm-1946	185	1	inborn	inborn	ADJ
ajlm-1946	185	2	errors	error	NOUN
ajlm-1946	185	3	of	of	ADP
ajlm-1946	185	4	metabolism	metabolism	NOUN
ajlm-1946	185	5	.	.	PUNCT
ajlm-1946	186	1	the	the	DET
ajlm-1946	186	2	croonian	croonian	ADJ
ajlm-1946	186	3	lectures	lecture	NOUN
ajlm-1946	186	4	.	.	PUNCT
ajlm-1946	187	1	london	london	PROPN
ajlm-1946	187	2	:	:	PUNCT
ajlm-1946	187	3	oxford	oxford	PROPN
ajlm-1946	187	4	university	university	PROPN
ajlm-1946	187	5	press	press	NOUN
ajlm-1946	187	6	;	;	PUNCT
ajlm-1946	187	7	1909	1909	NUM
ajlm-1946	187	8	.	.	PUNCT
ajlm-1946	188	1	garrod	garrod	PROPN
ajlm-1946	188	2	ae	ae	PROPN
ajlm-1946	188	3	.	.	PUNCT
ajlm-1946	189	1	the	the	DET
ajlm-1946	189	2	incidence	incidence	NOUN
ajlm-1946	189	3	of	of	ADP
ajlm-1946	189	4	alkaptonuria	alkaptonuria	NOUN
ajlm-1946	189	5	:	:	PUNCT
ajlm-1946	189	6	a	a	DET
ajlm-1946	189	7	study	study	NOUN
ajlm-1946	189	8	in	in	ADP
ajlm-1946	189	9	chemical	chemical	NOUN
ajlm-1946	189	10	individuality	individuality	NOUN
ajlm-1946	189	11	.	.	PUNCT
ajlm-1946	190	1	med	me	VERB
ajlm-1946	190	2	chir	chir	PROPN
ajlm-1946	190	3	trans	trans	PROPN
ajlm-1946	190	4	.	.	PUNCT
ajlm-1946	191	1	1902;85:69–78	1902;85:69–78	NUM
ajlm-1946	191	2	.	.	PUNCT
ajlm-1946	192	1	hortin	hortin	PROPN
ajlm-1946	192	2	gl	gl	PROPN
ajlm-1946	192	3	.	.	PROPN
ajlm-1946	192	4	amino	amino	PROPN
ajlm-1946	192	5	acids	acid	NOUN
ajlm-1946	192	6	,	,	PUNCT
ajlm-1946	192	7	peptides	peptide	NOUN
ajlm-1946	192	8	and	and	CCONJ
ajlm-1946	192	9	proteins	protein	NOUN
ajlm-1946	192	10	.	.	PUNCT
ajlm-1946	193	1	in	in	ADP
ajlm-1946	193	2	:	:	PUNCT
ajlm-1946	193	3	burtis	burtis	NOUN
ajlm-1946	193	4	ca	can	AUX
ajlm-1946	193	5	,	,	PUNCT
ajlm-1946	193	6	bruns	bruns	X
ajlm-1946	193	7	de	de	PROPN
ajlm-1946	193	8	,	,	PUNCT
ajlm-1946	193	9	editors	editor	NOUN
ajlm-1946	193	10	.	.	PUNCT
ajlm-1946	194	1	tietz	tietz	VERB
ajlm-1946	194	2	fundamentals	fundamental	NOUN
ajlm-1946	194	3	of	of	ADP
ajlm-1946	194	4	clinical	clinical	ADJ
ajlm-1946	194	5	chemistry	chemistry	NOUN
ajlm-1946	194	6	and	and	CCONJ
ajlm-1946	194	7	molecular	molecular	ADJ
ajlm-1946	194	8	diagnostics	diagnostic	NOUN
ajlm-1946	194	9	.	.	PUNCT
ajlm-1946	195	1	st	st	PROPN
ajlm-1946	195	2	.	.	PROPN
ajlm-1946	195	3	louis	louis	PROPN
ajlm-1946	195	4	,	,	PUNCT
ajlm-1946	195	5	mo	mo	PROPN
ajlm-1946	195	6	:	:	PUNCT
ajlm-1946	195	7	saunders	saunder	NOUN
ajlm-1946	195	8	,	,	PUNCT
ajlm-1946	195	9	elsevier	elsevier	PROPN
ajlm-1946	195	10	inc	inc	PROPN
ajlm-1946	195	11	.	.	PROPN
ajlm-1946	195	12	;	;	PUNCT
ajlm-1946	195	13	2015	2015	NUM
ajlm-1946	195	14	.	.	PUNCT
ajlm-1946	196	1	pp	pp	ADV
ajlm-1946	196	2	.	.	PUNCT
ajlm-1946	197	1	286–317	286–317	NUM
ajlm-1946	197	2	.	.	PUNCT
ajlm-1946	198	1	leonard	leonard	PROPN
ajlm-1946	198	2	jv	jv	PROPN
ajlm-1946	198	3	,	,	PUNCT
ajlm-1946	198	4	morris	morris	PROPN
ajlm-1946	198	5	aam	aam	PROPN
ajlm-1946	198	6	.	.	PUNCT
ajlm-1946	198	7	inborn	inborn	ADJ
ajlm-1946	198	8	errors	error	NOUN
ajlm-1946	198	9	of	of	ADP
ajlm-1946	198	10	metabolism	metabolism	NOUN
ajlm-1946	198	11	around	around	ADP
ajlm-1946	198	12	the	the	DET
ajlm-1946	198	13	time	time	NOUN
ajlm-1946	198	14	of	of	ADP
ajlm-1946	198	15	birth	birth	NOUN
ajlm-1946	198	16	.	.	PUNCT
ajlm-1946	199	1	lancet	lancet	NOUN
ajlm-1946	199	2	.	.	PUNCT
ajlm-1946	200	1	2000;356:583–587	2000;356:583–587	NUM
ajlm-1946	200	2	.	.	PUNCT
ajlm-1946	201	1	https://doi.org/10.1016/s0140-6736(00)02591-5	https://doi.org/10.1016/s0140-6736(00)02591-5	PROPN
ajlm-1946	201	2	marshall	marshall	PROPN
ajlm-1946	201	3	wj	wj	PROPN
ajlm-1946	201	4	,	,	PUNCT
ajlm-1946	201	5	lapsley	lapsley	PROPN
ajlm-1946	201	6	m	m	PROPN
ajlm-1946	201	7	,	,	PUNCT
ajlm-1946	201	8	day	day	NOUN
ajlm-1946	201	9	a	a	PRON
ajlm-1946	201	10	,	,	PUNCT
ajlm-1946	201	11	ayling	ayle	VERB
ajlm-1946	201	12	r.	r.	PROPN
ajlm-1946	201	13	clinical	clinical	ADJ
ajlm-1946	201	14	biochemistry	biochemistry	NOUN
ajlm-1946	201	15	:	:	PUNCT
ajlm-1946	201	16	metabolic	metabolic	NOUN
ajlm-1946	201	17	and	and	CCONJ
ajlm-1946	201	18	clinical	clinical	ADJ
ajlm-1946	201	19	aspects	aspect	NOUN
ajlm-1946	201	20	.	.	PUNCT
ajlm-1946	202	1	3rd	3rd	ADJ
ajlm-1946	202	2	ed	ed	NOUN
ajlm-1946	202	3	.	.	PUNCT
ajlm-1946	202	4	edinburgh	edinburgh	PROPN
ajlm-1946	202	5	:	:	PUNCT
ajlm-1946	202	6	churchill	churchill	PROPN
ajlm-1946	202	7	livingstone	livingstone	PROPN
ajlm-1946	202	8	,	,	PUNCT
ajlm-1946	202	9	2014	2014	NUM
ajlm-1946	202	10	;	;	PUNCT
ajlm-1946	203	1	pp	pp	ADP
ajlm-1946	203	2	.	.	PUNCT
ajlm-1946	204	1	461–483	461–483	NUM
ajlm-1946	204	2	.	.	X
ajlm-1946	204	3	institute	institute	PROPN
ajlm-1946	204	4	of	of	ADP
ajlm-1946	204	5	medicine	medicine	PROPN
ajlm-1946	204	6	committee	committee	PROPN
ajlm-1946	204	7	on	on	ADP
ajlm-1946	204	8	improving	improve	VERB
ajlm-1946	204	9	birth	birth	NOUN
ajlm-1946	204	10	o.	o.	NOUN
ajlm-1946	204	11	in	in	ADP
ajlm-1946	204	12	:	:	PUNCT
ajlm-1946	204	13	bale	bale	PROPN
ajlm-1946	204	14	jr	jr	PROPN
ajlm-1946	204	15	,	,	PUNCT
ajlm-1946	204	16	stoll	stoll	PROPN
ajlm-1946	204	17	bj	bj	PROPN
ajlm-1946	204	18	,	,	PUNCT
ajlm-1946	204	19	lucas	lucas	PROPN
ajlm-1946	204	20	ao	ao	PROPN
ajlm-1946	204	21	,	,	PUNCT
ajlm-1946	204	22	editors	editor	NOUN
ajlm-1946	204	23	.	.	PUNCT
ajlm-1946	205	1	reducing	reduce	VERB
ajlm-1946	205	2	birth	birth	NOUN
ajlm-1946	205	3	defects	defect	NOUN
ajlm-1946	205	4	:	:	PUNCT
ajlm-1946	205	5	meeting	meet	VERB
ajlm-1946	205	6	the	the	DET
ajlm-1946	205	7	challenge	challenge	NOUN
ajlm-1946	205	8	in	in	ADP
ajlm-1946	205	9	the	the	DET
ajlm-1946	205	10	developing	develop	VERB
ajlm-1946	205	11	world	world	NOUN
ajlm-1946	205	12	.	.	PUNCT
ajlm-1946	206	1	washington	washington	PROPN
ajlm-1946	206	2	(	(	PUNCT
ajlm-1946	206	3	dc	dc	PROPN
ajlm-1946	206	4	):	):	PUNCT
ajlm-1946	206	5	national	national	PROPN
ajlm-1946	206	6	academy	academy	PROPN
ajlm-1946	206	7	of	of	ADP
ajlm-1946	206	8	sciences	sciences	PROPN
ajlm-1946	206	9	press	press	PROPN
ajlm-1946	206	10	,	,	PUNCT
ajlm-1946	206	11	usa	usa	PROPN
ajlm-1946	206	12	;	;	PUNCT
ajlm-1946	206	13	2003	2003	NUM
ajlm-1946	206	14	.	.	PUNCT
ajlm-1946	207	1	weinhold	weinhold	PROPN
ajlm-1946	207	2	b.	b.	PROPN
ajlm-1946	207	3	environmental	environmental	ADJ
ajlm-1946	207	4	factors	factor	NOUN
ajlm-1946	207	5	in	in	ADP
ajlm-1946	207	6	birth	birth	NOUN
ajlm-1946	207	7	defects	defect	NOUN
ajlm-1946	207	8	:	:	PUNCT
ajlm-1946	207	9	what	what	PRON
ajlm-1946	207	10	we	we	PRON
ajlm-1946	207	11	need	need	VERB
ajlm-1946	207	12	to	to	PART
ajlm-1946	207	13	know	know	VERB
ajlm-1946	207	14	.	.	PUNCT
ajlm-1946	208	1	environ	environ	PROPN
ajlm-1946	208	2	health	health	NOUN
ajlm-1946	208	3	perspect	perspect	NOUN
ajlm-1946	208	4	.	.	PUNCT
ajlm-1946	209	1	2009;117(10):a440	2009;117(10):a440	X
ajlm-1946	209	2	–	–	PUNCT
ajlm-1946	209	3	a447	a447	PROPN
ajlm-1946	209	4	.	.	PUNCT
ajlm-1946	210	1	https://doi.org/10.1289/ehp.117-a440	https://doi.org/10.1289/ehp.117-a440	PROPN
ajlm-1946	210	2	arnold	arnold	PROPN
ajlm-1946	210	3	gl	gl	PROPN
ajlm-1946	210	4	.	.	PROPN
ajlm-1946	210	5	inborn	inborn	ADJ
ajlm-1946	210	6	errors	error	NOUN
ajlm-1946	210	7	of	of	ADP
ajlm-1946	210	8	metabolism	metabolism	NOUN
ajlm-1946	210	9	in	in	ADP
ajlm-1946	210	10	the	the	DET
ajlm-1946	210	11	21(st	21(st	NUM
ajlm-1946	210	12	)	)	PUNCT
ajlm-1946	210	13	century	century	NOUN
ajlm-1946	210	14	:	:	PUNCT
ajlm-1946	210	15	past	past	ADJ
ajlm-1946	210	16	to	to	PART
ajlm-1946	210	17	present	present	VERB
ajlm-1946	210	18	.	.	PUNCT
ajlm-1946	211	1	annals	annal	NOUN
ajlm-1946	211	2	of	of	ADP
ajlm-1946	211	3	translational	translational	ADJ
ajlm-1946	211	4	medicine	medicine	NOUN
ajlm-1946	211	5	.	.	PUNCT
ajlm-1946	212	1	2018;6(24):467	2018;6(24):467	X
ajlm-1946	212	2	.	.	PUNCT
ajlm-1946	213	1	https://doi.org/10.21037/atm.2018.11.36	https://doi.org/10.21037/atm.2018.11.36	PROPN
ajlm-1946	213	2	edwards	edwards	PROPN
ajlm-1946	213	3	tm	tm	PROPN
ajlm-1946	213	4	,	,	PUNCT
ajlm-1946	213	5	myers	myers	PROPN
ajlm-1946	213	6	jp	jp	PROPN
ajlm-1946	213	7	.	.	PUNCT
ajlm-1946	214	1	environmental	environmental	ADJ
ajlm-1946	214	2	exposures	exposure	NOUN
ajlm-1946	214	3	and	and	CCONJ
ajlm-1946	214	4	gene	gene	NOUN
ajlm-1946	214	5	regulation	regulation	NOUN
ajlm-1946	214	6	in	in	ADP
ajlm-1946	214	7	disease	disease	NOUN
ajlm-1946	214	8	etiology	etiology	NOUN
ajlm-1946	214	9	.	.	PUNCT
ajlm-1946	215	1	environ	environ	PROPN
ajlm-1946	215	2	health	health	NOUN
ajlm-1946	215	3	perspect	perspect	NOUN
ajlm-1946	215	4	.	.	PUNCT
ajlm-1946	216	1	2007;115(9):1264–70	2007;115(9):1264–70	NOUN
ajlm-1946	216	2	.	.	PUNCT
ajlm-1946	217	1	https://doi.org/10.1289/ehp.9951	https://doi.org/10.1289/ehp.9951	PROPN
ajlm-1946	217	2	echeverri	echeverri	NOUN
ajlm-1946	217	3	ox	ox	NOUN
ajlm-1946	217	4	,	,	PUNCT
ajlm-1946	217	5	guevara	guevara	PROPN
ajlm-1946	217	6	jm	jm	PROPN
ajlm-1946	217	7	,	,	PUNCT
ajlm-1946	217	8	espejo	espejo	PROPN
ajlm-1946	217	9	j	j	PROPN
ajlm-1946	217	10	,	,	PUNCT
ajlm-1946	217	11	et	et	PROPN
ajlm-1946	217	12	al	al	PROPN
ajlm-1946	217	13	.	.	PROPN
ajlm-1946	217	14	research	research	NOUN
ajlm-1946	217	15	,	,	PUNCT
ajlm-1946	217	16	diagnosis	diagnosis	NOUN
ajlm-1946	217	17	,	,	PUNCT
ajlm-1946	217	18	and	and	CCONJ
ajlm-1946	217	19	education	education	NOUN
ajlm-1946	217	20	in	in	ADP
ajlm-1946	217	21	inborn	inborn	ADJ
ajlm-1946	217	22	errors	error	NOUN
ajlm-1946	217	23	of	of	ADP
ajlm-1946	217	24	metabolism	metabolism	NOUN
ajlm-1946	217	25	in	in	ADP
ajlm-1946	217	26	colombia	colombia	PROPN
ajlm-1946	217	27	:	:	PUNCT
ajlm-1946	217	28	20	20	NUM
ajlm-1946	217	29	years	year	NOUN
ajlm-1946	217	30	’	'	PUNCT
ajlm-1946	217	31	experience	experience	NOUN
ajlm-1946	217	32	from	from	ADP
ajlm-1946	217	33	a	a	DET
ajlm-1946	217	34	reference	reference	NOUN
ajlm-1946	217	35	center	center	NOUN
ajlm-1946	217	36	.	.	PUNCT
ajlm-1946	218	1	orphanet	orphanet	PROPN
ajlm-1946	218	2	j	j	PROPN
ajlm-1946	218	3	rare	rare	ADJ
ajlm-1946	218	4	dis	dis	PROPN
ajlm-1946	218	5	.	.	PUNCT
ajlm-1946	219	1	2018;13(1):141	2018;13(1):141	NUM
ajlm-1946	219	2	.	.	PUNCT
ajlm-1946	220	1	https://doi.org/10.1186/s13023-018-0879-2	https://doi.org/10.1186/s13023-018-0879-2	NOUN
ajlm-1946	220	2	civallero	civallero	VERB
ajlm-1946	220	3	g	g	PROPN
ajlm-1946	220	4	,	,	PUNCT
ajlm-1946	220	5	de	de	PROPN
ajlm-1946	220	6	kremer	kremer	PROPN
ajlm-1946	220	7	r	r	PROPN
ajlm-1946	220	8	,	,	PUNCT
ajlm-1946	220	9	giugliani	giugliani	PROPN
ajlm-1946	220	10	r.	r.	PROPN
ajlm-1946	220	11	high	high	ADJ
ajlm-1946	220	12	-	-	PUNCT
ajlm-1946	220	13	risk	risk	NOUN
ajlm-1946	220	14	screening	screening	NOUN
ajlm-1946	220	15	and	and	CCONJ
ajlm-1946	220	16	diagnosis	diagnosis	NOUN
ajlm-1946	220	17	of	of	ADP
ajlm-1946	220	18	inborn	inborn	ADJ
ajlm-1946	220	19	errors	error	NOUN
ajlm-1946	220	20	of	of	ADP
ajlm-1946	220	21	metabolism	metabolism	NOUN
ajlm-1946	220	22	:	:	PUNCT
ajlm-1946	220	23	a	a	DET
ajlm-1946	220	24	practical	practical	ADJ
ajlm-1946	220	25	guide	guide	NOUN
ajlm-1946	220	26	for	for	ADP
ajlm-1946	220	27	laboratories	laboratory	NOUN
ajlm-1946	220	28	.	.	PUNCT
ajlm-1946	221	1	j	j	PROPN
ajlm-1946	221	2	inborn	inborn	ADJ
ajlm-1946	221	3	errors	error	NOUN
ajlm-1946	221	4	metab	metab	NOUN
ajlm-1946	221	5	screen	screen	NOUN
ajlm-1946	221	6	.	.	PUNCT
ajlm-1946	222	1	2018;6	2018;6	NOUN
ajlm-1946	222	2	.	.	PUNCT
ajlm-1946	223	1	https://doi.org/10.1177/2326409818792065	https://doi.org/10.1177/2326409818792065	PROPN
ajlm-1946	223	2	mayo	mayo	PROPN
ajlm-1946	223	3	clinic	clinic	PROPN
ajlm-1946	223	4	medical	medical	ADJ
ajlm-1946	223	5	laboratories	laboratory	NOUN
ajlm-1946	223	6	.	.	PUNCT
ajlm-1946	224	1	biochemical	biochemical	ADJ
ajlm-1946	224	2	genetics	genetic	NOUN
ajlm-1946	224	3	–	–	PUNCT
ajlm-1946	224	4	inborn	inborn	ADJ
ajlm-1946	224	5	errors	error	NOUN
ajlm-1946	224	6	of	of	ADP
ajlm-1946	224	7	metabolism	metabolism	NOUN
ajlm-1946	224	8	.	.	PUNCT
ajlm-1946	225	1	rochester	rochester	PROPN
ajlm-1946	225	2	,	,	PUNCT
ajlm-1946	225	3	mn	mn	PROPN
ajlm-1946	225	4	:	:	PUNCT
ajlm-1946	225	5	mayo	mayo	PROPN
ajlm-1946	225	6	foundation	foundation	PROPN
ajlm-1946	225	7	for	for	ADP
ajlm-1946	225	8	medical	medical	ADJ
ajlm-1946	225	9	education	education	NOUN
ajlm-1946	225	10	and	and	CCONJ
ajlm-1946	225	11	research	research	NOUN
ajlm-1946	225	12	;	;	PUNCT
ajlm-1946	225	13	2011	2011	NUM
ajlm-1946	225	14	.	.	PUNCT
ajlm-1946	226	1	fernandes	fernandes	PROPN
ajlm-1946	226	2	j	j	PROPN
ajlm-1946	226	3	,	,	PUNCT
ajlm-1946	226	4	saudubray	saudubray	PROPN
ajlm-1946	226	5	jm	jm	PROPN
ajlm-1946	226	6	,	,	PUNCT
ajlm-1946	226	7	van	van	PROPN
ajlm-1946	226	8	den	den	PROPN
ajlm-1946	226	9	berghe	berghe	NOUN
ajlm-1946	226	10	g.	g.	PROPN
ajlm-1946	226	11	inborn	inborn	ADJ
ajlm-1946	226	12	metabolic	metabolic	NOUN
ajlm-1946	226	13	diseases	disease	NOUN
ajlm-1946	226	14	:	:	PUNCT
ajlm-1946	226	15	diagnosis	diagnosis	NOUN
ajlm-1946	226	16	and	and	CCONJ
ajlm-1946	226	17	treatment	treatment	NOUN
ajlm-1946	226	18	.	.	PUNCT
ajlm-1946	227	1	4th	4th	ADJ
ajlm-1946	227	2	ed	ed	NOUN
ajlm-1946	227	3	.	.	PUNCT
ajlm-1946	228	1	berlin	berlin	PROPN
ajlm-1946	228	2	:	:	PUNCT
ajlm-1946	228	3	springer	springer	NOUN
ajlm-1946	228	4	verlag	verlag	PROPN
ajlm-1946	228	5	,	,	PUNCT
ajlm-1946	228	6	2000	2000	NUM
ajlm-1946	228	7	;	;	PUNCT
ajlm-1946	228	8	p.	p.	NOUN
ajlm-1946	228	9	561	561	NUM
ajlm-1946	228	10	.	.	PUNCT
ajlm-1946	229	1	brown	brown	PROPN
ajlm-1946	229	2	sm	sm	PROPN
ajlm-1946	229	3	,	,	PUNCT
ajlm-1946	229	4	lo	lo	PROPN
ajlm-1946	229	5	sf	sf	PROPN
ajlm-1946	229	6	.	.	PUNCT
ajlm-1946	229	7	inborn	inborn	ADJ
ajlm-1946	229	8	errors	error	NOUN
ajlm-1946	229	9	of	of	ADP
ajlm-1946	229	10	metabolism	metabolism	NOUN
ajlm-1946	229	11	.	.	PUNCT
ajlm-1946	230	1	in	in	ADP
ajlm-1946	230	2	:	:	PUNCT
ajlm-1946	230	3	clark	clark	PROPN
ajlm-1946	230	4	w	w	PROPN
ajlm-1946	230	5	,	,	PUNCT
ajlm-1946	230	6	editor	editor	NOUN
ajlm-1946	230	7	.	.	PUNCT
ajlm-1946	231	1	contemporary	contemporary	ADJ
ajlm-1946	231	2	practice	practice	NOUN
ajlm-1946	231	3	in	in	ADP
ajlm-1946	231	4	clinical	clinical	ADJ
ajlm-1946	231	5	chemistry	chemistry	NOUN
ajlm-1946	231	6	.	.	PUNCT
ajlm-1946	232	1	3rd	3rd	ADJ
ajlm-1946	232	2	ed	ed	NOUN
ajlm-1946	232	3	.	.	PUNCT
ajlm-1946	233	1	london	london	PROPN
ajlm-1946	233	2	:	:	PUNCT
ajlm-1946	233	3	aacc	aacc	PROPN
ajlm-1946	233	4	press	press	PROPN
ajlm-1946	233	5	,	,	PUNCT
ajlm-1946	233	6	2016	2016	NUM
ajlm-1946	233	7	;	;	PUNCT
ajlm-1946	233	8	p.	p.	NOUN
ajlm-1946	233	9	651	651	NUM
ajlm-1946	233	10	.	.	PUNCT
ajlm-1946	234	1	bakerman	bakerman	PROPN
ajlm-1946	234	2	s.	s.	PROPN
ajlm-1946	234	3	bakerman	bakerman	PROPN
ajlm-1946	234	4	’s	’s	PART
ajlm-1946	234	5	abc	abc	PROPN
ajlm-1946	234	6	of	of	ADP
ajlm-1946	234	7	interpretive	interpretive	ADJ
ajlm-1946	234	8	laboratory	laboratory	NOUN
ajlm-1946	234	9	data	datum	NOUN
ajlm-1946	234	10	.	.	PUNCT
ajlm-1946	235	1	chicago	chicago	PROPN
ajlm-1946	235	2	,	,	PUNCT
ajlm-1946	235	3	il	il	PROPN
ajlm-1946	235	4	:	:	PUNCT
ajlm-1946	235	5	yearbook	yearbook	VERB
ajlm-1946	235	6	medical	medical	ADJ
ajlm-1946	235	7	publishers	publisher	NOUN
ajlm-1946	235	8	;	;	PUNCT
ajlm-1946	235	9	2002	2002	NUM
ajlm-1946	235	10	.	.	PUNCT
ajlm-1946	236	1	stoller	stoller	PROPN
ajlm-1946	236	2	jk	jk	PROPN
ajlm-1946	236	3	,	,	PUNCT
ajlm-1946	236	4	hupertz	hupertz	PROPN
ajlm-1946	236	5	v	v	NOUN
ajlm-1946	236	6	,	,	PUNCT
ajlm-1946	236	7	aboussouan	aboussouan	ADP
ajlm-1946	236	8	ls	ls	PROPN
ajlm-1946	236	9	.	.	PUNCT
ajlm-1946	237	1	alpha-1	alpha-1	NUM
ajlm-1946	237	2	antitrypsin	antitrypsin	NOUN
ajlm-1946	237	3	deficiency	deficiency	NOUN
ajlm-1946	237	4	.	.	PUNCT
ajlm-1946	238	1	in	in	ADP
ajlm-1946	238	2	:	:	PUNCT
ajlm-1946	238	3	adam	adam	PROPN
ajlm-1946	238	4	mp	mp	PROPN
ajlm-1946	238	5	,	,	PUNCT
ajlm-1946	238	6	everman	everman	NOUN
ajlm-1946	238	7	db	db	PROPN
ajlm-1946	238	8	,	,	PUNCT
ajlm-1946	238	9	mirzaa	mirzaa	ADJ
ajlm-1946	238	10	gm	gm	PROPN
ajlm-1946	238	11	,	,	PUNCT
ajlm-1946	238	12	et	et	PROPN
ajlm-1946	238	13	al	al	PROPN
ajlm-1946	238	14	.	.	PROPN
ajlm-1946	238	15	,	,	PUNCT
ajlm-1946	238	16	editors	editor	NOUN
ajlm-1946	238	17	.	.	PUNCT
ajlm-1946	239	1	genereviews	genereview	NOUN
ajlm-1946	239	2	®	®	PROPN
ajlm-1946	239	3	.	.	PUNCT
ajlm-1946	240	1	seattle	seattle	PROPN
ajlm-1946	240	2	,	,	PUNCT
ajlm-1946	240	3	wa	wa	PROPN
ajlm-1946	240	4	:	:	PUNCT
ajlm-1946	240	5	university	university	PROPN
ajlm-1946	240	6	of	of	ADP
ajlm-1946	240	7	washington	washington	PROPN
ajlm-1946	240	8	,	,	PUNCT
ajlm-1946	240	9	2006	2006	NUM
ajlm-1946	240	10	;	;	PUNCT
ajlm-1946	240	11	pp	pp	PROPN
ajlm-1946	240	12	.	.	PUNCT
ajlm-1946	240	13	1993–2022	1993–2022	NUM
ajlm-1946	240	14	.	.	PUNCT
ajlm-1946	241	1	demir	demir	PROPN
ajlm-1946	241	2	n	n	CCONJ
ajlm-1946	241	3	,	,	PUNCT
ajlm-1946	241	4	diken	diken	PROPN
ajlm-1946	241	5	eo	eo	PROPN
ajlm-1946	241	6	,	,	PUNCT
ajlm-1946	241	7	karabulut	karabulut	PROPN
ajlm-1946	241	8	gh	gh	PROPN
ajlm-1946	241	9	,	,	PUNCT
ajlm-1946	241	10	karnak	karnak	PROPN
ajlm-1946	241	11	d	d	PROPN
ajlm-1946	241	12	,	,	PUNCT
ajlm-1946	241	13	kayacan	kayacan	PROPN
ajlm-1946	241	14	o.	o.	PROPN
ajlm-1946	241	15	alpha-1	alpha-1	PROPN
ajlm-1946	241	16	antitrypsin	antitrypsin	NOUN
ajlm-1946	241	17	levels	level	NOUN
ajlm-1946	241	18	and	and	CCONJ
ajlm-1946	241	19	polymorphisms	polymorphism	NOUN
ajlm-1946	241	20	in	in	ADP
ajlm-1946	241	21	interstitial	interstitial	ADJ
ajlm-1946	241	22	lung	lung	NOUN
ajlm-1946	241	23	diseases	disease	NOUN
ajlm-1946	241	24	.	.	PUNCT
ajlm-1946	242	1	turk	turk	PROPN
ajlm-1946	242	2	j	j	PROPN
ajlm-1946	242	3	med	med	PROPN
ajlm-1946	242	4	sci	sci	PROPN
ajlm-1946	242	5	.	.	PUNCT
ajlm-1946	243	1	2017;47(2):476–482	2017;47(2):476–482	NUM
ajlm-1946	243	2	.	.	PROPN
ajlm-1946	243	3	https://doi.org/10.3906/sag-1508-76	https://doi.org/10.3906/sag-1508-76	PROPN
ajlm-1946	243	4	nickle	nickle	PROPN
ajlm-1946	243	5	t	t	PROPN
ajlm-1946	243	6	,	,	PUNCT
ajlm-1946	243	7	barrette	barrette	NOUN
ajlm-1946	243	8	-	-	PUNCT
ajlm-1946	243	9	n	n	CCONJ
ajlm-1946	243	10	i.	i.	NOUN
ajlm-1946	243	11	mutation	mutation	NOUN
ajlm-1946	243	12	and	and	CCONJ
ajlm-1946	243	13	variation	variation	NOUN
ajlm-1946	243	14	usa	usa	PROPN
ajlm-1946	244	1	[	[	X
ajlm-1946	244	2	homepage	homepage	NOUN
ajlm-1946	244	3	on	on	ADP
ajlm-1946	244	4	the	the	DET
ajlm-1946	244	5	internet	internet	NOUN
ajlm-1946	244	6	]	]	PUNCT
ajlm-1946	244	7	.	.	PUNCT
ajlm-1946	245	1	libretexts	libretext	NOUN
ajlm-1946	245	2	;	;	PUNCT
ajlm-1946	245	3	c2021	c2021	PROPN
ajlm-1946	245	4	[	[	X
ajlm-1946	245	5	cited	cite	VERB
ajlm-1946	245	6	2021	2021	NUM
ajlm-1946	245	7	feb	feb	NOUN
ajlm-1946	245	8	01	01	NUM
ajlm-1946	245	9	]	]	PUNCT
ajlm-1946	245	10	.	.	PUNCT
ajlm-1946	246	1	available	available	ADJ
ajlm-1946	246	2	from	from	ADP
ajlm-1946	246	3	:	:	PUNCT
ajlm-1946	246	4	https://bio.libretexts.org/bookshelves/genetics/book%3a_online_open_genetics_(nickle_and_barrette-ng)/04%3a_mutation_and_variation	https://bio.libretexts.org/bookshelves/genetics/book%3a_online_open_genetics_(nickle_and_barrette-ng)/04%3a_mutation_and_variation	NOUN
ajlm-1946	246	5	ooi	ooi	PROPN
ajlm-1946	246	6	cy	cy	PROPN
ajlm-1946	246	7	,	,	PUNCT
ajlm-1946	246	8	durie	durie	VERB
ajlm-1946	246	9	pr	pr	NOUN
ajlm-1946	246	10	.	.	PUNCT
ajlm-1946	247	1	cystic	cystic	ADJ
ajlm-1946	247	2	fibrosis	fibrosis	NOUN
ajlm-1946	247	3	transmembrane	transmembrane	NOUN
ajlm-1946	247	4	conductance	conductance	NOUN
ajlm-1946	247	5	regulator	regulator	NOUN
ajlm-1946	247	6	(	(	PUNCT
ajlm-1946	247	7	cftr	cftr	NOUN
ajlm-1946	247	8	)	)	PUNCT
ajlm-1946	247	9	gene	gene	NOUN
ajlm-1946	247	10	mutations	mutation	NOUN
ajlm-1946	247	11	in	in	ADP
ajlm-1946	247	12	pancreatitis	pancreatitis	PROPN
ajlm-1946	247	13	.	.	PUNCT
ajlm-1946	248	1	j	j	PROPN
ajlm-1946	248	2	cyst	cyst	NOUN
ajlm-1946	248	3	fibrosis	fibrosis	NOUN
ajlm-1946	248	4	.	.	PUNCT
ajlm-1946	249	1	2012;11(5):35–562	2012;11(5):35–562	NUM
ajlm-1946	249	2	.	.	PUNCT
ajlm-1946	250	1	https://doi.org/10.1016/j.jcf.2012.05.001	https://doi.org/10.1016/j.jcf.2012.05.001	PROPN
ajlm-1946	250	2	gibson	gibson	PROPN
ajlm-1946	250	3	-	-	PUNCT
ajlm-1946	250	4	corley	corley	PROPN
ajlm-1946	250	5	kn	kn	PROPN
ajlm-1946	250	6	,	,	PUNCT
ajlm-1946	250	7	meyerholz	meyerholz	PROPN
ajlm-1946	250	8	dk	dk	PROPN
ajlm-1946	250	9	,	,	PUNCT
ajlm-1946	250	10	engelhardt	engelhardt	PROPN
ajlm-1946	250	11	jf	jf	PROPN
ajlm-1946	250	12	.	.	PROPN
ajlm-1946	250	13	pancreatic	pancreatic	ADJ
ajlm-1946	250	14	pathophysiology	pathophysiology	NOUN
ajlm-1946	250	15	in	in	ADP
ajlm-1946	250	16	cystic	cystic	ADJ
ajlm-1946	250	17	fibrosis	fibrosis	NOUN
ajlm-1946	250	18	.	.	PUNCT
ajlm-1946	251	1	j	j	PROPN
ajlm-1946	251	2	pathol	pathol	NOUN
ajlm-1946	251	3	.	.	PUNCT
ajlm-1946	252	1	2016;238(2):311–320	2016;238(2):311–320	X
ajlm-1946	252	2	.	.	PROPN
ajlm-1946	252	3	https://doi.org/10.1002/path.4634	https://doi.org/10.1002/path.4634	NOUN
ajlm-1946	252	4	schmidt	schmidt	PROPN
ajlm-1946	252	5	h	h	PROPN
ajlm-1946	252	6	,	,	PUNCT
ajlm-1946	252	7	sharma	sharma	PROPN
ajlm-1946	252	8	g.	g.	PROPN
ajlm-1946	252	9	sweat	sweat	PROPN
ajlm-1946	252	10	testing	testing	NOUN
ajlm-1946	252	11	.	.	PUNCT
ajlm-1946	253	1	in	in	ADP
ajlm-1946	253	2	:	:	PUNCT
ajlm-1946	253	3	statpearls	statpearl	NOUN
ajlm-1946	254	1	[	[	X
ajlm-1946	254	2	homepage	homepage	NOUN
ajlm-1946	254	3	on	on	ADP
ajlm-1946	254	4	the	the	DET
ajlm-1946	254	5	internet	internet	NOUN
ajlm-1946	254	6	]	]	PUNCT
ajlm-1946	254	7	.	.	PUNCT
ajlm-1946	255	1	treasure	treasure	NOUN
ajlm-1946	255	2	island	island	NOUN
ajlm-1946	255	3	,	,	PUNCT
ajlm-1946	255	4	fl	fl	PROPN
ajlm-1946	255	5	:	:	PUNCT
ajlm-1946	255	6	statpearls	statpearls	PROPN
ajlm-1946	255	7	publishing	publishing	NOUN
ajlm-1946	255	8	;	;	PUNCT
ajlm-1946	255	9	2022	2022	NUM
ajlm-1946	255	10	[	[	X
ajlm-1946	255	11	updated	update	VERB
ajlm-1946	255	12	2022	2022	NUM
ajlm-1946	255	13	may	may	AUX
ajlm-1946	255	14	08	08	NUM
ajlm-1946	255	15	]	]	PUNCT
ajlm-1946	255	16	.	.	PUNCT
ajlm-1946	256	1	available	available	ADJ
ajlm-1946	256	2	from	from	ADP
ajlm-1946	256	3	:	:	PUNCT
ajlm-1946	256	4	https://www.ncbi.nlm.nih.gov/books/nbk547728/	https://www.ncbi.nlm.nih.gov/books/nbk547728/	PROPN
ajlm-1946	256	5	timson	timson	NOUN
ajlm-1946	256	6	dj	dj	NOUN
ajlm-1946	256	7	.	.	PUNCT
ajlm-1946	257	1	the	the	DET
ajlm-1946	257	2	molecular	molecular	ADJ
ajlm-1946	257	3	basis	basis	NOUN
ajlm-1946	257	4	of	of	ADP
ajlm-1946	257	5	galactosemia	galactosemia	NOUN
ajlm-1946	257	6	–	–	PUNCT
ajlm-1946	257	7	past	past	ADP
ajlm-1946	257	8	present	present	NOUN
ajlm-1946	257	9	and	and	CCONJ
ajlm-1946	257	10	future	future	NOUN
ajlm-1946	257	11	.	.	PUNCT
ajlm-1946	258	1	gene	gene	NOUN
ajlm-1946	258	2	.	.	PUNCT
ajlm-1946	259	1	2015;589(2):133–141	2015;589(2):133–141	X
ajlm-1946	259	2	.	.	X
ajlm-1946	260	1	https://doi.org/10.1016/j.gene.2015.06.077	https://doi.org/10.1016/j.gene.2015.06.077	PROPN
ajlm-1946	260	2	green	green	PROPN
ajlm-1946	260	3	a	a	PROPN
ajlm-1946	260	4	,	,	PUNCT
ajlm-1946	261	1	morgan	morgan	PROPN
ajlm-1946	261	2	i	i	PROPN
ajlm-1946	261	3	,	,	PUNCT
ajlm-1946	261	4	gray	gray	ADJ
ajlm-1946	261	5	j.	j.	PROPN
ajlm-1946	261	6	neonatology	neonatology	PROPN
ajlm-1946	261	7	and	and	CCONJ
ajlm-1946	261	8	laboratory	laboratory	NOUN
ajlm-1946	261	9	medicine	medicine	NOUN
ajlm-1946	261	10	.	.	PUNCT
ajlm-1946	262	1	london	london	PROPN
ajlm-1946	262	2	:	:	PUNCT
ajlm-1946	262	3	acb	acb	PROPN
ajlm-1946	262	4	venture	venture	NOUN
ajlm-1946	262	5	publication	publication	NOUN
ajlm-1946	262	6	;	;	PUNCT
ajlm-1946	262	7	2003	2003	NUM
ajlm-1946	262	8	.	.	PUNCT
ajlm-1946	263	1	sciver	sciver	PROPN
ajlm-1946	263	2	cr	cr	PROPN
ajlm-1946	263	3	,	,	PUNCT
ajlm-1946	263	4	beaudet	beaudet	PROPN
ajlm-1946	263	5	al	al	PROPN
ajlm-1946	263	6	,	,	PUNCT
ajlm-1946	263	7	sly	sly	ADJ
ajlm-1946	263	8	wl	wl	PROPN
ajlm-1946	263	9	,	,	PUNCT
ajlm-1946	263	10	et	et	PROPN
ajlm-1946	263	11	al	al	PROPN
ajlm-1946	263	12	.	.	PROPN
ajlm-1946	263	13	,	,	PUNCT
ajlm-1946	263	14	editors	editor	NOUN
ajlm-1946	263	15	.	.	PUNCT
ajlm-1946	264	1	the	the	DET
ajlm-1946	264	2	metabolic	metabolic	NOUN
ajlm-1946	264	3	and	and	CCONJ
ajlm-1946	264	4	molecular	molecular	ADJ
ajlm-1946	264	5	basis	basis	NOUN
ajlm-1946	264	6	of	of	ADP
ajlm-1946	264	7	inherited	inherit	VERB
ajlm-1946	264	8	disease	disease	NOUN
ajlm-1946	264	9	.	.	PUNCT
ajlm-1946	265	1	8th	8th	ADJ
ajlm-1946	265	2	ed	ed	NOUN
ajlm-1946	265	3	.	.	PUNCT
ajlm-1946	266	1	new	new	PROPN
ajlm-1946	266	2	york	york	PROPN
ajlm-1946	266	3	,	,	PUNCT
ajlm-1946	266	4	ny	ny	PROPN
ajlm-1946	266	5	:	:	PUNCT
ajlm-1946	266	6	mcgraw	mcgraw	PROPN
ajlm-1946	266	7	-	-	PUNCT
ajlm-1946	266	8	hill	hill	NOUN
ajlm-1946	266	9	;	;	PUNCT
ajlm-1946	266	10	2001	2001	NUM
ajlm-1946	266	11	.	.	PUNCT
ajlm-1946	267	1	peters	peters	PROPN
ajlm-1946	267	2	tj	tj	PROPN
ajlm-1946	267	3	,	,	PUNCT
ajlm-1946	267	4	sarkany	sarkany	PROPN
ajlm-1946	267	5	r.	r.	PROPN
ajlm-1946	267	6	porphyria	porphyria	PROPN
ajlm-1946	267	7	for	for	ADP
ajlm-1946	267	8	the	the	DET
ajlm-1946	267	9	general	general	ADJ
ajlm-1946	267	10	physician	physician	NOUN
ajlm-1946	267	11	.	.	PUNCT
ajlm-1946	268	1	clin	clin	PROPN
ajlm-1946	268	2	med	med	PROPN
ajlm-1946	268	3	.	.	PUNCT
ajlm-1946	269	1	2005;5(3):275–281	2005;5(3):275–281	X
ajlm-1946	269	2	.	.	PUNCT
ajlm-1946	270	1	https://doi.org/10.7861/clinmedicine.5-3-275	https://doi.org/10.7861/clinmedicine.5-3-275	PROPN
ajlm-1946	270	2	anderson	anderson	PROPN
ajlm-1946	270	3	ka	ka	PROPN
ajlm-1946	270	4	,	,	PUNCT
ajlm-1946	270	5	sassa	sassa	NOUN
ajlm-1946	270	6	s	s	PROPN
ajlm-1946	270	7	,	,	PUNCT
ajlm-1946	270	8	bishop	bishop	PROPN
ajlm-1946	270	9	d	d	PROPN
ajlm-1946	270	10	,	,	PUNCT
ajlm-1946	270	11	desnick	desnick	PROPN
ajlm-1946	270	12	r.	r.	NOUN
ajlm-1946	270	13	disorders	disorder	NOUN
ajlm-1946	270	14	of	of	ADP
ajlm-1946	270	15	heme	heme	NOUN
ajlm-1946	270	16	biosynthesis	biosynthesis	NOUN
ajlm-1946	270	17	:	:	PUNCT
ajlm-1946	270	18	x	x	X
ajlm-1946	270	19	-	-	ADJ
ajlm-1946	270	20	linked	link	VERB
ajlm-1946	270	21	sideroblastic	sideroblastic	ADJ
ajlm-1946	270	22	anemia	anemia	NOUN
ajlm-1946	270	23	and	and	CCONJ
ajlm-1946	270	24	the	the	DET
ajlm-1946	270	25	porphyrias	porphyria	NOUN
ajlm-1946	270	26	.	.	PUNCT
ajlm-1946	271	1	in	in	ADP
ajlm-1946	271	2	:	:	PUNCT
ajlm-1946	271	3	sciver	sciver	PROPN
ajlm-1946	271	4	c	c	PROPN
ajlm-1946	271	5	,	,	PUNCT
ajlm-1946	271	6	beaudet	beaudet	NOUN
ajlm-1946	271	7	a	a	DET
ajlm-1946	271	8	,	,	PUNCT
ajlm-1946	271	9	sly	sly	ADJ
ajlm-1946	271	10	w	w	NOUN
ajlm-1946	271	11	,	,	PUNCT
ajlm-1946	271	12	valle	valle	PROPN
ajlm-1946	271	13	d	d	NOUN
ajlm-1946	271	14	,	,	PUNCT
ajlm-1946	271	15	childs	child	VERB
ajlm-1946	271	16	b	b	NOUN
ajlm-1946	271	17	,	,	PUNCT
ajlm-1946	271	18	editors	editor	NOUN
ajlm-1946	271	19	.	.	PUNCT
ajlm-1946	272	1	metabolic	metabolic	NOUN
ajlm-1946	272	2	and	and	CCONJ
ajlm-1946	272	3	molecular	molecular	ADJ
ajlm-1946	272	4	bases	basis	NOUN
ajlm-1946	272	5	of	of	ADP
ajlm-1946	272	6	inherited	inherit	VERB
ajlm-1946	272	7	disease	disease	NOUN
ajlm-1946	273	1	[	[	X
ajlm-1946	273	2	homepage	homepage	NOUN
ajlm-1946	273	3	on	on	ADP
ajlm-1946	273	4	the	the	DET
ajlm-1946	273	5	internet	internet	NOUN
ajlm-1946	273	6	]	]	PUNCT
ajlm-1946	273	7	.	.	PUNCT
ajlm-1946	274	1	new	new	PROPN
ajlm-1946	274	2	york	york	PROPN
ajlm-1946	274	3	,	,	PUNCT
ajlm-1946	274	4	ny	ny	PROPN
ajlm-1946	274	5	:	:	PUNCT
ajlm-1946	274	6	mcgraw	mcgraw	PROPN
ajlm-1946	274	7	-	-	PUNCT
ajlm-1946	274	8	hill	hill	NOUN
ajlm-1946	274	9	,	,	PUNCT
ajlm-1946	274	10	2001	2001	NUM
ajlm-1946	274	11	;	;	PUNCT
ajlm-1946	274	12	pp	pp	NUM
ajlm-1946	274	13	.	.	PUNCT
ajlm-1946	275	1	2991–3062	2991–3062	NUM
ajlm-1946	275	2	.	.	PUNCT
ajlm-1946	276	1	shedlofsky	shedlofsky	PROPN
ajlm-1946	276	2	si	si	PROPN
ajlm-1946	276	3	.	.	PUNCT
ajlm-1946	276	4	young	young	ADJ
ajlm-1946	276	5	woman	woman	NOUN
ajlm-1946	276	6	with	with	ADP
ajlm-1946	276	7	recurrent	recurrent	ADJ
ajlm-1946	276	8	abdominal	abdominal	ADJ
ajlm-1946	276	9	pain	pain	NOUN
ajlm-1946	276	10	.	.	PUNCT
ajlm-1946	277	1	in	in	ADP
ajlm-1946	277	2	:	:	PUNCT
ajlm-1946	277	3	scott	scott	PROPN
ajlm-1946	277	4	mg	mg	PROPN
ajlm-1946	277	5	,	,	PUNCT
ajlm-1946	277	6	grownowski	grownowski	NOUN
ajlm-1946	277	7	am	am	NOUN
ajlm-1946	277	8	,	,	PUNCT
ajlm-1946	277	9	eby	eby	PROPN
ajlm-1946	277	10	cs	cs	PROPN
ajlm-1946	277	11	,	,	PUNCT
ajlm-1946	277	12	editors	editor	NOUN
ajlm-1946	277	13	.	.	PUNCT
ajlm-1946	278	1	tietz	tietz	VERB
ajlm-1946	278	2	’s	’s	PART
ajlm-1946	278	3	applied	apply	VERB
ajlm-1946	278	4	laboratory	laboratory	NOUN
ajlm-1946	278	5	medicine	medicine	NOUN
ajlm-1946	278	6	.	.	PUNCT
ajlm-1946	279	1	hoboken	hoboken	PROPN
ajlm-1946	279	2	,	,	PUNCT
ajlm-1946	279	3	nj	nj	PROPN
ajlm-1946	279	4	:	:	PUNCT
ajlm-1946	279	5	john	john	PROPN
ajlm-1946	279	6	wiley	wiley	PROPN
ajlm-1946	279	7	,	,	PUNCT
ajlm-1946	279	8	2007	2007	NUM
ajlm-1946	279	9	;	;	PUNCT
ajlm-1946	279	10	pp	pp	ADP
ajlm-1946	279	11	.	.	PUNCT
ajlm-1946	280	1	513–522	513–522	NUM
ajlm-1946	280	2	.	.	PUNCT
ajlm-1946	280	3	ain	ain	PROPN
ajlm-1946	280	4	.	.	PUNCT
ajlm-1946	281	1	the	the	DET
ajlm-1946	281	2	fatigued	fatigue	VERB
ajlm-1946	281	3	attorney	attorney	NOUN
ajlm-1946	281	4	.	.	PUNCT
ajlm-1946	282	1	in	in	ADP
ajlm-1946	282	2	:	:	PUNCT
ajlm-1946	282	3	scott	scott	PROPN
ajlm-1946	282	4	mg	mg	PROPN
ajlm-1946	282	5	,	,	PUNCT
ajlm-1946	282	6	grownowski	grownowski	NOUN
ajlm-1946	282	7	am	am	NOUN
ajlm-1946	282	8	,	,	PUNCT
ajlm-1946	282	9	eby	eby	PROPN
ajlm-1946	282	10	cs	cs	PROPN
ajlm-1946	282	11	,	,	PUNCT
ajlm-1946	282	12	editors	editor	NOUN
ajlm-1946	282	13	.	.	PUNCT
ajlm-1946	283	1	tietz	tietz	VERB
ajlm-1946	283	2	’s	’s	PART
ajlm-1946	283	3	applied	apply	VERB
ajlm-1946	283	4	laboratory	laboratory	NOUN
ajlm-1946	283	5	medicine	medicine	NOUN
ajlm-1946	283	6	.	.	PUNCT
ajlm-1946	284	1	hoboken	hoboken	PROPN
ajlm-1946	284	2	,	,	PUNCT
ajlm-1946	284	3	nj	nj	PROPN
ajlm-1946	284	4	:	:	PUNCT
ajlm-1946	284	5	john	john	PROPN
ajlm-1946	284	6	wiley	wiley	PROPN
ajlm-1946	284	7	,	,	PUNCT
ajlm-1946	284	8	2007	2007	NUM
ajlm-1946	284	9	;	;	PUNCT
ajlm-1946	284	10	pp	pp	ADP
ajlm-1946	284	11	.	.	PUNCT
ajlm-1946	285	1	513–522	513–522	NUM
ajlm-1946	285	2	.	.	PUNCT
ajlm-1946	286	1	demers	demers	PROPN
ajlm-1946	286	2	lm	lm	PROPN
ajlm-1946	286	3	,	,	PUNCT
ajlm-1946	286	4	spencer	spencer	PROPN
ajlm-1946	286	5	ca	ca	PROPN
ajlm-1946	286	6	.	.	PUNCT
ajlm-1946	287	1	laboratory	laboratory	PROPN
ajlm-1946	287	2	medicine	medicine	NOUN
ajlm-1946	287	3	practice	practice	NOUN
ajlm-1946	287	4	guidelines	guideline	NOUN
ajlm-1946	287	5	:	:	PUNCT
ajlm-1946	287	6	laboratory	laboratory	NOUN
ajlm-1946	287	7	support	support	NOUN
ajlm-1946	287	8	for	for	ADP
ajlm-1946	287	9	the	the	DET
ajlm-1946	287	10	diagnosis	diagnosis	NOUN
ajlm-1946	287	11	and	and	CCONJ
ajlm-1946	287	12	monitoring	monitoring	NOUN
ajlm-1946	287	13	of	of	ADP
ajlm-1946	287	14	thyroid	thyroid	NOUN
ajlm-1946	287	15	disease	disease	NOUN
ajlm-1946	287	16	.	.	PUNCT
ajlm-1946	288	1	clin	clin	PROPN
ajlm-1946	288	2	endocrinol	endocrinol	PROPN
ajlm-1946	288	3	(	(	PUNCT
ajlm-1946	288	4	oxf	oxf	PROPN
ajlm-1946	288	5	)	)	PUNCT
ajlm-1946	288	6	.	.	PUNCT
ajlm-1946	289	1	2003;58(2):138–140	2003;58(2):138–140	NUM
ajlm-1946	289	2	.	.	PUNCT
ajlm-1946	289	3	https://doi.org/10.1046/j.1365-2265.2003.01681.x	https://doi.org/10.1046/j.1365-2265.2003.01681.x	NOUN
ajlm-1946	289	4	anetor	anetor	PROPN
ajlm-1946	289	5	ji	ji	PROPN
ajlm-1946	289	6	,	,	PUNCT
ajlm-1946	289	7	durojaiye	durojaiye	VERB
ajlm-1946	289	8	oo	oo	PROPN
ajlm-1946	289	9	,	,	PUNCT
ajlm-1946	289	10	iyanda	iyanda	PROPN
ajlm-1946	289	11	a	a	PRON
ajlm-1946	289	12	,	,	PUNCT
ajlm-1946	289	13	adeniyi	adeniyi	ADV
ajlm-1946	289	14	a	a	PRON
ajlm-1946	289	15	,	,	PUNCT
ajlm-1946	289	16	agbedana	agbedana	PROPN
ajlm-1946	289	17	eo	eo	PROPN
ajlm-1946	289	18	.	.	PROPN
ajlm-1946	289	19	a	a	DET
ajlm-1946	289	20	basic	basic	ADJ
ajlm-1946	289	21	investigation	investigation	NOUN
ajlm-1946	289	22	for	for	ADP
ajlm-1946	289	23	inherited	inherit	VERB
ajlm-1946	289	24	metabolic	metabolic	NOUN
ajlm-1946	289	25	disease	disease	NOUN
ajlm-1946	289	26	in	in	ADP
ajlm-1946	289	27	two	two	NUM
ajlm-1946	289	28	institutions	institution	NOUN
ajlm-1946	289	29	for	for	ADP
ajlm-1946	289	30	the	the	DET
ajlm-1946	289	31	handicapped	handicap	VERB
ajlm-1946	289	32	in	in	ADP
ajlm-1946	289	33	ibadan	ibadan	NOUN
ajlm-1946	289	34	:	:	PUNCT
ajlm-1946	289	35	indication	indication	NOUN
ajlm-1946	289	36	for	for	ADP
ajlm-1946	289	37	genomics	genomic	NOUN
ajlm-1946	289	38	.	.	PUNCT
ajlm-1946	290	1	j	j	PROPN
ajlm-1946	290	2	biomed	biome	VERB
ajlm-1946	290	3	invest	invest	NOUN
ajlm-1946	290	4	.	.	PUNCT
ajlm-1946	291	1	2006;4(1):23–27	2006;4(1):23–27	NUM
ajlm-1946	291	2	.	.	PUNCT
ajlm-1946	292	1	https://doi.org/10.4314/jbi.v4i1.30411	https://doi.org/10.4314/jbi.v4i1.30411	VERB
ajlm-1946	292	2	kruszka	kruszka	PROPN
ajlm-1946	293	1	p	p	NOUN
ajlm-1946	293	2	,	,	PUNCT
ajlm-1946	293	3	regier	regi	ADJ
ajlm-1946	293	4	d.	d.	PROPN
ajlm-1946	293	5	inborn	inborn	ADJ
ajlm-1946	293	6	errors	error	NOUN
ajlm-1946	293	7	of	of	ADP
ajlm-1946	293	8	metabolism	metabolism	NOUN
ajlm-1946	293	9	:	:	PUNCT
ajlm-1946	293	10	from	from	ADP
ajlm-1946	293	11	preconception	preconception	NOUN
ajlm-1946	293	12	to	to	ADP
ajlm-1946	293	13	adulthood	adulthood	NOUN
ajlm-1946	293	14	.	.	PUNCT
ajlm-1946	294	1	am	be	AUX
ajlm-1946	294	2	fam	fam	NOUN
ajlm-1946	294	3	physician	physician	NOUN
ajlm-1946	294	4	.	.	PUNCT
ajlm-1946	295	1	2019;99(1):25–32	2019;99(1):25–32	X
ajlm-1946	295	2	.	.	PUNCT