id	sid	tid	token	lemma	pos
ajlm-1975	1	1	abstract	abstract	ADJ
ajlm-1975	1	2	introduction	introduction	NOUN
ajlm-1975	1	3	methods	method	NOUN
ajlm-1975	1	4	results	result	VERB
ajlm-1975	1	5	discussion	discussion	NOUN
ajlm-1975	1	6	acknowledgements	acknowledgement	NOUN
ajlm-1975	1	7	references	reference	NOUN
ajlm-1975	1	8	about	about	ADP
ajlm-1975	1	9	the	the	DET
ajlm-1975	1	10	author(s	author(s	NOUN
ajlm-1975	1	11	)	)	PUNCT
ajlm-1975	1	12	nomonde	nomonde	PROPN
ajlm-1975	1	13	r.	r.	PROPN
ajlm-1975	1	14	mvelase	mvelase	PROPN
ajlm-1975	1	15	department	department	PROPN
ajlm-1975	1	16	of	of	ADP
ajlm-1975	1	17	medical	medical	ADJ
ajlm-1975	1	18	microbiology	microbiology	NOUN
ajlm-1975	1	19	,	,	PUNCT
ajlm-1975	1	20	kwazulu	kwazulu	VERB
ajlm-1975	1	21	-	-	PUNCT
ajlm-1975	1	22	natal	natal	ADJ
ajlm-1975	1	23	academic	academic	ADJ
ajlm-1975	1	24	complex	complex	NOUN
ajlm-1975	1	25	,	,	PUNCT
ajlm-1975	1	26	national	national	ADJ
ajlm-1975	1	27	health	health	PROPN
ajlm-1975	1	28	laboratory	laboratory	PROPN
ajlm-1975	1	29	service	service	PROPN
ajlm-1975	1	30	,	,	PUNCT
ajlm-1975	1	31	durban	durban	PROPN
ajlm-1975	1	32	,	,	PUNCT
ajlm-1975	1	33	south	south	PROPN
ajlm-1975	1	34	africa	africa	PROPN
ajlm-1975	1	35	school	school	PROPN
ajlm-1975	1	36	of	of	ADP
ajlm-1975	1	37	laboratory	laboratory	NOUN
ajlm-1975	1	38	medicine	medicine	NOUN
ajlm-1975	1	39	and	and	CCONJ
ajlm-1975	1	40	medical	medical	ADJ
ajlm-1975	1	41	sciences	science	NOUN
ajlm-1975	1	42	,	,	PUNCT
ajlm-1975	1	43	college	college	NOUN
ajlm-1975	1	44	of	of	ADP
ajlm-1975	1	45	health	health	PROPN
ajlm-1975	1	46	sciences	sciences	PROPN
ajlm-1975	1	47	,	,	PUNCT
ajlm-1975	1	48	university	university	NOUN
ajlm-1975	1	49	of	of	ADP
ajlm-1975	1	50	kwazulu	kwazulu	PROPN
ajlm-1975	1	51	-	-	PUNCT
ajlm-1975	1	52	natal	natal	ADJ
ajlm-1975	1	53	,	,	PUNCT
ajlm-1975	1	54	durban	durban	PROPN
ajlm-1975	1	55	,	,	PUNCT
ajlm-1975	1	56	south	south	PROPN
ajlm-1975	1	57	africa	africa	PROPN
ajlm-1975	1	58	lindiwe	lindiwe	PROPN
ajlm-1975	1	59	p.	p.	PROPN
ajlm-1975	1	60	cele	cele	PROPN
ajlm-1975	2	1	department	department	PROPN
ajlm-1975	2	2	of	of	ADP
ajlm-1975	2	3	public	public	ADJ
ajlm-1975	2	4	health	health	NOUN
ajlm-1975	2	5	,	,	PUNCT
ajlm-1975	2	6	epidemiology	epidemiology	NOUN
ajlm-1975	2	7	and	and	CCONJ
ajlm-1975	2	8	biostatistics	biostatistic	NOUN
ajlm-1975	2	9	unit	unit	NOUN
ajlm-1975	2	10	,	,	PUNCT
ajlm-1975	2	11	sefako	sefako	VERB
ajlm-1975	2	12	makgatho	makgatho	PROPN
ajlm-1975	2	13	health	health	PROPN
ajlm-1975	2	14	sciences	sciences	PROPN
ajlm-1975	2	15	university	university	PROPN
ajlm-1975	2	16	,	,	PUNCT
ajlm-1975	2	17	pretoria	pretoria	PROPN
ajlm-1975	2	18	,	,	PUNCT
ajlm-1975	2	19	south	south	PROPN
ajlm-1975	2	20	africa	africa	PROPN
ajlm-1975	2	21	ravesh	ravesh	PROPN
ajlm-1975	2	22	singh	singh	PROPN
ajlm-1975	2	23	department	department	PROPN
ajlm-1975	2	24	of	of	ADP
ajlm-1975	2	25	medical	medical	ADJ
ajlm-1975	2	26	microbiology	microbiology	NOUN
ajlm-1975	2	27	,	,	PUNCT
ajlm-1975	2	28	kwazulu	kwazulu	VERB
ajlm-1975	2	29	-	-	PUNCT
ajlm-1975	2	30	natal	natal	ADJ
ajlm-1975	2	31	academic	academic	ADJ
ajlm-1975	2	32	complex	complex	NOUN
ajlm-1975	2	33	,	,	PUNCT
ajlm-1975	2	34	national	national	ADJ
ajlm-1975	2	35	health	health	PROPN
ajlm-1975	2	36	laboratory	laboratory	PROPN
ajlm-1975	2	37	service	service	PROPN
ajlm-1975	2	38	,	,	PUNCT
ajlm-1975	2	39	durban	durban	PROPN
ajlm-1975	2	40	,	,	PUNCT
ajlm-1975	2	41	south	south	PROPN
ajlm-1975	2	42	africa	africa	PROPN
ajlm-1975	2	43	school	school	PROPN
ajlm-1975	2	44	of	of	ADP
ajlm-1975	2	45	laboratory	laboratory	NOUN
ajlm-1975	2	46	medicine	medicine	NOUN
ajlm-1975	2	47	and	and	CCONJ
ajlm-1975	2	48	medical	medical	ADJ
ajlm-1975	2	49	sciences	science	NOUN
ajlm-1975	2	50	,	,	PUNCT
ajlm-1975	2	51	college	college	NOUN
ajlm-1975	2	52	of	of	ADP
ajlm-1975	2	53	health	health	PROPN
ajlm-1975	2	54	sciences	sciences	PROPN
ajlm-1975	2	55	,	,	PUNCT
ajlm-1975	2	56	university	university	NOUN
ajlm-1975	2	57	of	of	ADP
ajlm-1975	2	58	kwazulu	kwazulu	PROPN
ajlm-1975	2	59	-	-	PUNCT
ajlm-1975	2	60	natal	natal	ADJ
ajlm-1975	2	61	,	,	PUNCT
ajlm-1975	2	62	durban	durban	PROPN
ajlm-1975	2	63	,	,	PUNCT
ajlm-1975	2	64	south	south	PROPN
ajlm-1975	2	65	africa	africa	PROPN
ajlm-1975	2	66	yeshnee	yeshnee	PROPN
ajlm-1975	2	67	naidoo	naidoo	PROPN
ajlm-1975	2	68	kwazulu	kwazulu	PROPN
ajlm-1975	2	69	-	-	PUNCT
ajlm-1975	2	70	natal	natal	ADJ
ajlm-1975	2	71	research	research	NOUN
ajlm-1975	2	72	innovation	innovation	NOUN
ajlm-1975	2	73	and	and	CCONJ
ajlm-1975	2	74	sequencing	sequence	VERB
ajlm-1975	2	75	platform	platform	NOUN
ajlm-1975	2	76	,	,	PUNCT
ajlm-1975	2	77	nelson	nelson	PROPN
ajlm-1975	2	78	r	r	PROPN
ajlm-1975	2	79	mandela	mandela	PROPN
ajlm-1975	2	80	school	school	NOUN
ajlm-1975	2	81	of	of	ADP
ajlm-1975	2	82	medicine	medicine	NOUN
ajlm-1975	2	83	,	,	PUNCT
ajlm-1975	2	84	university	university	NOUN
ajlm-1975	2	85	of	of	ADP
ajlm-1975	2	86	kwazulu	kwazulu	PROPN
ajlm-1975	2	87	-	-	PUNCT
ajlm-1975	2	88	natal	natal	ADJ
ajlm-1975	2	89	,	,	PUNCT
ajlm-1975	2	90	durban	durban	PROPN
ajlm-1975	2	91	,	,	PUNCT
ajlm-1975	2	92	south	south	PROPN
ajlm-1975	2	93	africa	africa	PROPN
ajlm-1975	2	94	centre	centre	PROPN
ajlm-1975	2	95	for	for	ADP
ajlm-1975	2	96	epidemic	epidemic	NOUN
ajlm-1975	2	97	response	response	NOUN
ajlm-1975	2	98	and	and	CCONJ
ajlm-1975	2	99	innovation	innovation	NOUN
ajlm-1975	2	100	,	,	PUNCT
ajlm-1975	2	101	school	school	NOUN
ajlm-1975	2	102	of	of	ADP
ajlm-1975	2	103	data	datum	NOUN
ajlm-1975	2	104	science	science	NOUN
ajlm-1975	2	105	and	and	CCONJ
ajlm-1975	2	106	computational	computational	ADJ
ajlm-1975	2	107	thinking	thinking	NOUN
ajlm-1975	2	108	,	,	PUNCT
ajlm-1975	2	109	stellenbosch	stellenbosch	PROPN
ajlm-1975	2	110	university	university	PROPN
ajlm-1975	2	111	,	,	PUNCT
ajlm-1975	2	112	stellenbosch	stellenbosch	PROPN
ajlm-1975	2	113	,	,	PUNCT
ajlm-1975	2	114	south	south	PROPN
ajlm-1975	2	115	africa	africa	PROPN
ajlm-1975	2	116	jennifer	jennifer	PROPN
ajlm-1975	2	117	giandhari	giandhari	PROPN
ajlm-1975	2	118	kwazulu	kwazulu	PROPN
ajlm-1975	2	119	-	-	PUNCT
ajlm-1975	2	120	natal	natal	ADJ
ajlm-1975	2	121	research	research	NOUN
ajlm-1975	2	122	innovation	innovation	NOUN
ajlm-1975	2	123	and	and	CCONJ
ajlm-1975	2	124	sequencing	sequence	VERB
ajlm-1975	2	125	platform	platform	NOUN
ajlm-1975	2	126	,	,	PUNCT
ajlm-1975	2	127	nelson	nelson	PROPN
ajlm-1975	2	128	r	r	PROPN
ajlm-1975	2	129	mandela	mandela	PROPN
ajlm-1975	2	130	school	school	NOUN
ajlm-1975	2	131	of	of	ADP
ajlm-1975	2	132	medicine	medicine	NOUN
ajlm-1975	2	133	,	,	PUNCT
ajlm-1975	2	134	university	university	NOUN
ajlm-1975	2	135	of	of	ADP
ajlm-1975	2	136	kwazulu	kwazulu	PROPN
ajlm-1975	2	137	-	-	PUNCT
ajlm-1975	2	138	natal	natal	ADJ
ajlm-1975	2	139	,	,	PUNCT
ajlm-1975	2	140	durban	durban	PROPN
ajlm-1975	2	141	,	,	PUNCT
ajlm-1975	2	142	south	south	PROPN
ajlm-1975	2	143	africa	africa	PROPN
ajlm-1975	2	144	eduan	eduan	PROPN
ajlm-1975	2	145	wilkinson	wilkinson	PROPN
ajlm-1975	2	146	kwazulu	kwazulu	PROPN
ajlm-1975	2	147	-	-	PUNCT
ajlm-1975	2	148	natal	natal	ADJ
ajlm-1975	2	149	research	research	NOUN
ajlm-1975	2	150	innovation	innovation	NOUN
ajlm-1975	2	151	and	and	CCONJ
ajlm-1975	2	152	sequencing	sequence	VERB
ajlm-1975	2	153	platform	platform	NOUN
ajlm-1975	2	154	,	,	PUNCT
ajlm-1975	2	155	nelson	nelson	PROPN
ajlm-1975	2	156	r	r	PROPN
ajlm-1975	2	157	mandela	mandela	PROPN
ajlm-1975	2	158	school	school	NOUN
ajlm-1975	2	159	of	of	ADP
ajlm-1975	2	160	medicine	medicine	NOUN
ajlm-1975	2	161	,	,	PUNCT
ajlm-1975	2	162	university	university	NOUN
ajlm-1975	2	163	of	of	ADP
ajlm-1975	2	164	kwazulu	kwazulu	PROPN
ajlm-1975	2	165	-	-	PUNCT
ajlm-1975	2	166	natal	natal	ADJ
ajlm-1975	2	167	,	,	PUNCT
ajlm-1975	2	168	durban	durban	PROPN
ajlm-1975	2	169	,	,	PUNCT
ajlm-1975	2	170	south	south	PROPN
ajlm-1975	2	171	africa	africa	PROPN
ajlm-1975	2	172	centre	centre	PROPN
ajlm-1975	2	173	for	for	ADP
ajlm-1975	2	174	epidemic	epidemic	NOUN
ajlm-1975	2	175	response	response	NOUN
ajlm-1975	2	176	and	and	CCONJ
ajlm-1975	2	177	innovation	innovation	NOUN
ajlm-1975	2	178	,	,	PUNCT
ajlm-1975	2	179	school	school	NOUN
ajlm-1975	2	180	of	of	ADP
ajlm-1975	2	181	data	datum	NOUN
ajlm-1975	2	182	science	science	NOUN
ajlm-1975	2	183	and	and	CCONJ
ajlm-1975	2	184	computational	computational	ADJ
ajlm-1975	2	185	thinking	thinking	NOUN
ajlm-1975	2	186	,	,	PUNCT
ajlm-1975	2	187	stellenbosch	stellenbosch	PROPN
ajlm-1975	2	188	university	university	PROPN
ajlm-1975	2	189	,	,	PUNCT
ajlm-1975	2	190	stellenbosch	stellenbosch	PROPN
ajlm-1975	2	191	,	,	PUNCT
ajlm-1975	2	192	south	south	PROPN
ajlm-1975	2	193	africa	africa	PROPN
ajlm-1975	2	194	tulio	tulio	PROPN
ajlm-1975	2	195	de	de	PROPN
ajlm-1975	2	196	oliveira	oliveira	PROPN
ajlm-1975	2	197	kwazulu	kwazulu	PROPN
ajlm-1975	2	198	-	-	PUNCT
ajlm-1975	2	199	natal	natal	ADJ
ajlm-1975	2	200	research	research	NOUN
ajlm-1975	2	201	innovation	innovation	NOUN
ajlm-1975	2	202	and	and	CCONJ
ajlm-1975	2	203	sequencing	sequence	VERB
ajlm-1975	2	204	platform	platform	NOUN
ajlm-1975	2	205	,	,	PUNCT
ajlm-1975	2	206	nelson	nelson	PROPN
ajlm-1975	2	207	r	r	PROPN
ajlm-1975	2	208	mandela	mandela	PROPN
ajlm-1975	2	209	school	school	NOUN
ajlm-1975	2	210	of	of	ADP
ajlm-1975	2	211	medicine	medicine	NOUN
ajlm-1975	2	212	,	,	PUNCT
ajlm-1975	2	213	university	university	NOUN
ajlm-1975	2	214	of	of	ADP
ajlm-1975	2	215	kwazulu	kwazulu	PROPN
ajlm-1975	2	216	-	-	PUNCT
ajlm-1975	2	217	natal	natal	ADJ
ajlm-1975	2	218	,	,	PUNCT
ajlm-1975	2	219	durban	durban	PROPN
ajlm-1975	2	220	,	,	PUNCT
ajlm-1975	2	221	south	south	PROPN
ajlm-1975	2	222	africa	africa	PROPN
ajlm-1975	2	223	centre	centre	PROPN
ajlm-1975	2	224	for	for	ADP
ajlm-1975	2	225	epidemic	epidemic	NOUN
ajlm-1975	2	226	response	response	NOUN
ajlm-1975	2	227	and	and	CCONJ
ajlm-1975	2	228	innovation	innovation	NOUN
ajlm-1975	2	229	,	,	PUNCT
ajlm-1975	2	230	school	school	NOUN
ajlm-1975	2	231	of	of	ADP
ajlm-1975	2	232	data	datum	NOUN
ajlm-1975	2	233	science	science	NOUN
ajlm-1975	2	234	and	and	CCONJ
ajlm-1975	2	235	computational	computational	ADJ
ajlm-1975	2	236	thinking	thinking	NOUN
ajlm-1975	2	237	,	,	PUNCT
ajlm-1975	2	238	stellenbosch	stellenbosch	PROPN
ajlm-1975	2	239	university	university	PROPN
ajlm-1975	2	240	,	,	PUNCT
ajlm-1975	2	241	stellenbosch	stellenbosch	PROPN
ajlm-1975	2	242	,	,	PUNCT
ajlm-1975	2	243	south	south	PROPN
ajlm-1975	2	244	africa	africa	PROPN
ajlm-1975	2	245	centre	centre	PROPN
ajlm-1975	2	246	for	for	ADP
ajlm-1975	2	247	the	the	DET
ajlm-1975	2	248	aids	aids	PROPN
ajlm-1975	2	249	programme	programme	NOUN
ajlm-1975	2	250	of	of	ADP
ajlm-1975	2	251	research	research	NOUN
ajlm-1975	2	252	in	in	ADP
ajlm-1975	2	253	south	south	PROPN
ajlm-1975	2	254	africa	africa	PROPN
ajlm-1975	2	255	,	,	PUNCT
ajlm-1975	2	256	university	university	PROPN
ajlm-1975	2	257	of	of	ADP
ajlm-1975	2	258	kwazulu	kwazulu	PROPN
ajlm-1975	2	259	-	-	PUNCT
ajlm-1975	2	260	natal	natal	ADJ
ajlm-1975	2	261	,	,	PUNCT
ajlm-1975	2	262	durban	durban	PROPN
ajlm-1975	2	263	,	,	PUNCT
ajlm-1975	2	264	south	south	PROPN
ajlm-1975	2	265	africa	africa	PROPN
ajlm-1975	2	266	khine	khine	PROPN
ajlm-1975	2	267	swe	swe	PROPN
ajlm-1975	2	268	swe	swe	PROPN
ajlm-1975	2	269	-	-	PUNCT
ajlm-1975	2	270	han	han	PROPN
ajlm-1975	2	271	department	department	PROPN
ajlm-1975	2	272	of	of	ADP
ajlm-1975	2	273	medical	medical	ADJ
ajlm-1975	2	274	microbiology	microbiology	NOUN
ajlm-1975	2	275	,	,	PUNCT
ajlm-1975	2	276	kwazulu	kwazulu	VERB
ajlm-1975	2	277	-	-	PUNCT
ajlm-1975	2	278	natal	natal	ADJ
ajlm-1975	2	279	academic	academic	ADJ
ajlm-1975	2	280	complex	complex	NOUN
ajlm-1975	2	281	,	,	PUNCT
ajlm-1975	2	282	national	national	ADJ
ajlm-1975	2	283	health	health	PROPN
ajlm-1975	2	284	laboratory	laboratory	PROPN
ajlm-1975	2	285	service	service	PROPN
ajlm-1975	2	286	,	,	PUNCT
ajlm-1975	2	287	durban	durban	PROPN
ajlm-1975	2	288	,	,	PUNCT
ajlm-1975	2	289	south	south	PROPN
ajlm-1975	2	290	africa	africa	PROPN
ajlm-1975	2	291	school	school	PROPN
ajlm-1975	2	292	of	of	ADP
ajlm-1975	2	293	laboratory	laboratory	NOUN
ajlm-1975	2	294	medicine	medicine	NOUN
ajlm-1975	2	295	and	and	CCONJ
ajlm-1975	2	296	medical	medical	ADJ
ajlm-1975	2	297	sciences	science	NOUN
ajlm-1975	2	298	,	,	PUNCT
ajlm-1975	2	299	college	college	NOUN
ajlm-1975	2	300	of	of	ADP
ajlm-1975	2	301	health	health	PROPN
ajlm-1975	2	302	sciences	sciences	PROPN
ajlm-1975	2	303	,	,	PUNCT
ajlm-1975	2	304	university	university	NOUN
ajlm-1975	2	305	of	of	ADP
ajlm-1975	2	306	kwazulu	kwazulu	PROPN
ajlm-1975	2	307	-	-	PUNCT
ajlm-1975	2	308	natal	natal	ADJ
ajlm-1975	2	309	,	,	PUNCT
ajlm-1975	2	310	durban	durban	PROPN
ajlm-1975	2	311	,	,	PUNCT
ajlm-1975	2	312	south	south	PROPN
ajlm-1975	2	313	africa	africa	PROPN
ajlm-1975	2	314	koleka	koleka	PROPN
ajlm-1975	3	1	p.	p.	PROPN
ajlm-1975	3	2	mlisana	mlisana	PROPN
ajlm-1975	3	3	department	department	PROPN
ajlm-1975	3	4	of	of	ADP
ajlm-1975	3	5	medical	medical	ADJ
ajlm-1975	3	6	microbiology	microbiology	NOUN
ajlm-1975	3	7	,	,	PUNCT
ajlm-1975	3	8	kwazulu	kwazulu	VERB
ajlm-1975	3	9	-	-	PUNCT
ajlm-1975	3	10	natal	natal	ADJ
ajlm-1975	3	11	academic	academic	ADJ
ajlm-1975	3	12	complex	complex	NOUN
ajlm-1975	3	13	,	,	PUNCT
ajlm-1975	3	14	national	national	ADJ
ajlm-1975	3	15	health	health	PROPN
ajlm-1975	3	16	laboratory	laboratory	PROPN
ajlm-1975	3	17	service	service	PROPN
ajlm-1975	3	18	,	,	PUNCT
ajlm-1975	3	19	durban	durban	PROPN
ajlm-1975	3	20	,	,	PUNCT
ajlm-1975	3	21	south	south	PROPN
ajlm-1975	3	22	africa	africa	PROPN
ajlm-1975	3	23	school	school	PROPN
ajlm-1975	3	24	of	of	ADP
ajlm-1975	3	25	laboratory	laboratory	NOUN
ajlm-1975	3	26	medicine	medicine	NOUN
ajlm-1975	3	27	and	and	CCONJ
ajlm-1975	3	28	medical	medical	ADJ
ajlm-1975	3	29	sciences	science	NOUN
ajlm-1975	3	30	,	,	PUNCT
ajlm-1975	3	31	college	college	NOUN
ajlm-1975	3	32	of	of	ADP
ajlm-1975	3	33	health	health	PROPN
ajlm-1975	3	34	sciences	sciences	PROPN
ajlm-1975	3	35	,	,	PUNCT
ajlm-1975	3	36	university	university	NOUN
ajlm-1975	3	37	of	of	ADP
ajlm-1975	3	38	kwazulu	kwazulu	PROPN
ajlm-1975	3	39	-	-	PUNCT
ajlm-1975	3	40	natal	natal	ADJ
ajlm-1975	3	41	,	,	PUNCT
ajlm-1975	3	42	durban	durban	PROPN
ajlm-1975	3	43	,	,	PUNCT
ajlm-1975	3	44	south	south	PROPN
ajlm-1975	3	45	africa	africa	PROPN
ajlm-1975	3	46	centre	centre	PROPN
ajlm-1975	3	47	for	for	ADP
ajlm-1975	3	48	the	the	DET
ajlm-1975	3	49	aids	aids	PROPN
ajlm-1975	3	50	programme	programme	NOUN
ajlm-1975	3	51	of	of	ADP
ajlm-1975	3	52	research	research	NOUN
ajlm-1975	3	53	in	in	ADP
ajlm-1975	3	54	south	south	PROPN
ajlm-1975	3	55	africa	africa	PROPN
ajlm-1975	3	56	,	,	PUNCT
ajlm-1975	3	57	university	university	PROPN
ajlm-1975	3	58	of	of	ADP
ajlm-1975	3	59	kwazulu	kwazulu	PROPN
ajlm-1975	3	60	-	-	PUNCT
ajlm-1975	3	61	natal	natal	ADJ
ajlm-1975	3	62	,	,	PUNCT
ajlm-1975	3	63	durban	durban	PROPN
ajlm-1975	3	64	,	,	PUNCT
ajlm-1975	3	65	south	south	PROPN
ajlm-1975	3	66	africa	africa	PROPN
ajlm-1975	3	67	citation	citation	PROPN
ajlm-1975	3	68	mvelase	mvelase	PROPN
ajlm-1975	3	69	nr	nr	PROPN
ajlm-1975	3	70	,	,	PUNCT
ajlm-1975	3	71	cele	cele	PROPN
ajlm-1975	3	72	lp	lp	PROPN
ajlm-1975	3	73	,	,	PUNCT
ajlm-1975	3	74	singh	singh	PROPN
ajlm-1975	3	75	r	r	PROPN
ajlm-1975	3	76	,	,	PUNCT
ajlm-1975	3	77	et	et	PROPN
ajlm-1975	3	78	al	al	PROPN
ajlm-1975	3	79	.	.	PUNCT
ajlm-1975	4	1	consequences	consequence	NOUN
ajlm-1975	4	2	of	of	ADP
ajlm-1975	4	3	rpob	rpob	ADJ
ajlm-1975	4	4	mutations	mutation	NOUN
ajlm-1975	4	5	missed	miss	VERB
ajlm-1975	4	6	by	by	ADP
ajlm-1975	4	7	the	the	DET
ajlm-1975	4	8	genotype	genotype	NOUN
ajlm-1975	4	9	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	4	10	assay	assay	NOUN
ajlm-1975	4	11	in	in	ADP
ajlm-1975	4	12	a	a	DET
ajlm-1975	4	13	programmatic	programmatic	ADJ
ajlm-1975	4	14	setting	setting	NOUN
ajlm-1975	4	15	in	in	ADP
ajlm-1975	4	16	south	south	PROPN
ajlm-1975	4	17	africa	africa	PROPN
ajlm-1975	4	18	.	.	PUNCT
ajlm-1975	5	1	afr	afr	PROPN
ajlm-1975	5	2	j	j	PROPN
ajlm-1975	5	3	lab	lab	PROPN
ajlm-1975	5	4	med	med	PROPN
ajlm-1975	5	5	.	.	PUNCT
ajlm-1975	6	1	2023;12(1	2023;12(1	NUM
ajlm-1975	6	2	)	)	PUNCT
ajlm-1975	6	3	,	,	PUNCT
ajlm-1975	7	1	a1975	a1975	PROPN
ajlm-1975	7	2	.	.	PUNCT
ajlm-1975	8	1	https://doi.org/10.4102/ajlm.v12i1.1975	https://doi.org/10.4102/ajlm.v12i1.1975	X
ajlm-1975	8	2	original	original	ADJ
ajlm-1975	8	3	research	research	NOUN
ajlm-1975	8	4	consequences	consequence	NOUN
ajlm-1975	8	5	of	of	ADP
ajlm-1975	8	6	rpob	rpob	ADJ
ajlm-1975	8	7	mutations	mutation	NOUN
ajlm-1975	8	8	missed	miss	VERB
ajlm-1975	8	9	by	by	ADP
ajlm-1975	8	10	the	the	DET
ajlm-1975	8	11	genotype	genotype	NOUN
ajlm-1975	8	12	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	8	13	assay	assay	NOUN
ajlm-1975	8	14	in	in	ADP
ajlm-1975	8	15	a	a	DET
ajlm-1975	8	16	programmatic	programmatic	ADJ
ajlm-1975	8	17	setting	setting	NOUN
ajlm-1975	8	18	in	in	ADP
ajlm-1975	8	19	south	south	PROPN
ajlm-1975	8	20	africa	africa	PROPN
ajlm-1975	8	21	nomonde	nomonde	PROPN
ajlm-1975	8	22	r.	r.	PROPN
ajlm-1975	8	23	mvelase	mvelase	PROPN
ajlm-1975	8	24	,	,	PUNCT
ajlm-1975	8	25	lindiwe	lindiwe	PROPN
ajlm-1975	8	26	p.	p.	PROPN
ajlm-1975	8	27	cele	cele	PROPN
ajlm-1975	8	28	,	,	PUNCT
ajlm-1975	8	29	ravesh	ravesh	PROPN
ajlm-1975	8	30	singh	singh	PROPN
ajlm-1975	8	31	,	,	PUNCT
ajlm-1975	8	32	yeshnee	yeshnee	PROPN
ajlm-1975	8	33	naidoo	naidoo	PROPN
ajlm-1975	8	34	,	,	PUNCT
ajlm-1975	8	35	jennifer	jennifer	PROPN
ajlm-1975	8	36	giandhari	giandhari	PROPN
ajlm-1975	8	37	,	,	PUNCT
ajlm-1975	8	38	eduan	eduan	PROPN
ajlm-1975	8	39	wilkinson	wilkinson	PROPN
ajlm-1975	8	40	,	,	PUNCT
ajlm-1975	8	41	tulio	tulio	PROPN
ajlm-1975	8	42	de	de	PROPN
ajlm-1975	8	43	oliveira	oliveira	PROPN
ajlm-1975	8	44	,	,	PUNCT
ajlm-1975	8	45	khine	khine	PROPN
ajlm-1975	8	46	swe	swe	PROPN
ajlm-1975	8	47	swe	swe	PROPN
ajlm-1975	8	48	-	-	PUNCT
ajlm-1975	8	49	han	han	PROPN
ajlm-1975	8	50	,	,	PUNCT
ajlm-1975	8	51	koleka	koleka	PROPN
ajlm-1975	8	52	p.	p.	PROPN
ajlm-1975	8	53	mlisana	mlisana	PROPN
ajlm-1975	8	54	received	receive	VERB
ajlm-1975	8	55	:	:	PUNCT
ajlm-1975	8	56	06	06	NUM
ajlm-1975	8	57	june	june	PROPN
ajlm-1975	8	58	2022	2022	NUM
ajlm-1975	8	59	;	;	PUNCT
ajlm-1975	8	60	accepted	accept	VERB
ajlm-1975	8	61	:	:	PUNCT
ajlm-1975	8	62	24	24	NUM
ajlm-1975	8	63	oct	oct	PROPN
ajlm-1975	8	64	.	.	PROPN
ajlm-1975	8	65	2022	2022	NUM
ajlm-1975	8	66	;	;	PUNCT
ajlm-1975	8	67	published	publish	VERB
ajlm-1975	8	68	:	:	PUNCT
ajlm-1975	8	69	06	06	NUM
ajlm-1975	8	70	feb	feb	X
ajlm-1975	8	71	.	.	PROPN
ajlm-1975	9	1	2023	2023	NUM
ajlm-1975	9	2	copyright	copyright	NOUN
ajlm-1975	9	3	:	:	PUNCT
ajlm-1975	9	4	©	©	PROPN
ajlm-1975	9	5	2023	2023	NUM
ajlm-1975	9	6	.	.	PUNCT
ajlm-1975	10	1	the	the	DET
ajlm-1975	10	2	author(s	author(s	NOUN
ajlm-1975	10	3	)	)	PUNCT
ajlm-1975	10	4	.	.	PUNCT
ajlm-1975	11	1	licensee	licensee	NOUN
ajlm-1975	11	2	:	:	PUNCT
ajlm-1975	11	3	aosis	aosis	NOUN
ajlm-1975	11	4	.	.	PUNCT
ajlm-1975	12	1	this	this	PRON
ajlm-1975	12	2	is	be	AUX
ajlm-1975	12	3	an	an	DET
ajlm-1975	12	4	open	open	ADJ
ajlm-1975	12	5	access	access	NOUN
ajlm-1975	12	6	article	article	NOUN
ajlm-1975	12	7	distributed	distribute	VERB
ajlm-1975	12	8	under	under	ADP
ajlm-1975	12	9	the	the	DET
ajlm-1975	12	10	terms	term	NOUN
ajlm-1975	12	11	of	of	ADP
ajlm-1975	12	12	the	the	DET
ajlm-1975	12	13	creative	creative	ADJ
ajlm-1975	12	14	commons	common	NOUN
ajlm-1975	12	15	attribution	attribution	NOUN
ajlm-1975	12	16	license	license	NOUN
ajlm-1975	12	17	,	,	PUNCT
ajlm-1975	12	18	which	which	PRON
ajlm-1975	12	19	permits	permit	VERB
ajlm-1975	12	20	unrestricted	unrestricted	ADJ
ajlm-1975	12	21	use	use	NOUN
ajlm-1975	12	22	,	,	PUNCT
ajlm-1975	12	23	distribution	distribution	NOUN
ajlm-1975	12	24	,	,	PUNCT
ajlm-1975	12	25	and	and	CCONJ
ajlm-1975	12	26	reproduction	reproduction	NOUN
ajlm-1975	12	27	in	in	ADP
ajlm-1975	12	28	any	any	DET
ajlm-1975	12	29	medium	medium	NOUN
ajlm-1975	12	30	,	,	PUNCT
ajlm-1975	12	31	provided	provide	VERB
ajlm-1975	12	32	the	the	DET
ajlm-1975	12	33	original	original	ADJ
ajlm-1975	12	34	work	work	NOUN
ajlm-1975	12	35	is	be	AUX
ajlm-1975	12	36	properly	properly	ADV
ajlm-1975	12	37	cited	cite	VERB
ajlm-1975	12	38	.	.	PUNCT
ajlm-1975	13	1	abstract	abstract	ADJ
ajlm-1975	13	2	background	background	NOUN
ajlm-1975	13	3	:	:	PUNCT
ajlm-1975	13	4	rifampicin	rifampicin	VERB
ajlm-1975	13	5	resistance	resistance	NOUN
ajlm-1975	13	6	missed	miss	VERB
ajlm-1975	13	7	by	by	ADP
ajlm-1975	13	8	commercial	commercial	ADJ
ajlm-1975	13	9	rapid	rapid	ADJ
ajlm-1975	13	10	molecular	molecular	ADJ
ajlm-1975	13	11	assays	assay	NOUN
ajlm-1975	13	12	but	but	CCONJ
ajlm-1975	13	13	detected	detect	VERB
ajlm-1975	13	14	by	by	ADP
ajlm-1975	13	15	phenotypic	phenotypic	ADJ
ajlm-1975	13	16	assays	assay	NOUN
ajlm-1975	13	17	may	may	AUX
ajlm-1975	13	18	lead	lead	VERB
ajlm-1975	13	19	to	to	ADP
ajlm-1975	13	20	discordant	discordant	ADJ
ajlm-1975	13	21	susceptibility	susceptibility	NOUN
ajlm-1975	13	22	results	result	NOUN
ajlm-1975	13	23	and	and	CCONJ
ajlm-1975	13	24	affect	affect	VERB
ajlm-1975	13	25	patient	patient	ADJ
ajlm-1975	13	26	management	management	NOUN
ajlm-1975	13	27	.	.	PUNCT
ajlm-1975	14	1	objective	objective	NOUN
ajlm-1975	14	2	:	:	PUNCT
ajlm-1975	14	3	this	this	DET
ajlm-1975	14	4	study	study	NOUN
ajlm-1975	14	5	was	be	AUX
ajlm-1975	14	6	conducted	conduct	VERB
ajlm-1975	14	7	to	to	PART
ajlm-1975	14	8	evaluate	evaluate	VERB
ajlm-1975	14	9	the	the	DET
ajlm-1975	14	10	causes	cause	NOUN
ajlm-1975	14	11	of	of	ADP
ajlm-1975	14	12	rifampicin	rifampicin	VERB
ajlm-1975	14	13	resistance	resistance	NOUN
ajlm-1975	14	14	missed	miss	VERB
ajlm-1975	14	15	by	by	ADP
ajlm-1975	14	16	the	the	DET
ajlm-1975	14	17	genotype	genotype	NOUN
ajlm-1975	14	18	mtbdrplus	mtbdrplus	NOUN
ajlm-1975	14	19	and	and	CCONJ
ajlm-1975	14	20	its	its	PRON
ajlm-1975	14	21	impact	impact	NOUN
ajlm-1975	14	22	on	on	ADP
ajlm-1975	14	23	the	the	DET
ajlm-1975	14	24	programmatic	programmatic	ADJ
ajlm-1975	14	25	management	management	NOUN
ajlm-1975	14	26	of	of	ADP
ajlm-1975	14	27	tuberculosis	tuberculosis	NOUN
ajlm-1975	14	28	in	in	ADP
ajlm-1975	14	29	kwazulu	kwazulu	NOUN
ajlm-1975	14	30	-	-	PUNCT
ajlm-1975	14	31	natal	natal	ADJ
ajlm-1975	14	32	,	,	PUNCT
ajlm-1975	14	33	south	south	PROPN
ajlm-1975	14	34	africa	africa	PROPN
ajlm-1975	14	35	.	.	PUNCT
ajlm-1975	15	1	methods	method	NOUN
ajlm-1975	15	2	:	:	PUNCT
ajlm-1975	15	3	we	we	PRON
ajlm-1975	15	4	analysed	analyse	VERB
ajlm-1975	15	5	routine	routine	ADJ
ajlm-1975	15	6	tuberculosis	tuberculosis	NOUN
ajlm-1975	15	7	programme	programme	NOUN
ajlm-1975	15	8	data	datum	NOUN
ajlm-1975	15	9	from	from	ADP
ajlm-1975	15	10	january	january	PROPN
ajlm-1975	15	11	2014	2014	NUM
ajlm-1975	15	12	to	to	ADP
ajlm-1975	15	13	december	december	PROPN
ajlm-1975	15	14	2014	2014	NUM
ajlm-1975	15	15	on	on	ADP
ajlm-1975	15	16	isolates	isolate	NOUN
ajlm-1975	15	17	showing	show	VERB
ajlm-1975	15	18	rifampicin	rifampicin	VERB
ajlm-1975	15	19	susceptibility	susceptibility	NOUN
ajlm-1975	15	20	on	on	ADP
ajlm-1975	15	21	the	the	DET
ajlm-1975	15	22	genotype	genotype	NOUN
ajlm-1975	15	23	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	15	24	assay	assay	NOUN
ajlm-1975	15	25	but	but	CCONJ
ajlm-1975	15	26	resistance	resistance	NOUN
ajlm-1975	15	27	on	on	ADP
ajlm-1975	15	28	the	the	DET
ajlm-1975	15	29	phenotypic	phenotypic	NOUN
ajlm-1975	15	30	agar	agar	NOUN
ajlm-1975	15	31	proportion	proportion	NOUN
ajlm-1975	15	32	method	method	NOUN
ajlm-1975	15	33	.	.	PUNCT
ajlm-1975	16	1	whole	whole	ADJ
ajlm-1975	16	2	-	-	PUNCT
ajlm-1975	16	3	genome	genome	NOUN
ajlm-1975	16	4	sequencing	sequencing	NOUN
ajlm-1975	16	5	was	be	AUX
ajlm-1975	16	6	performed	perform	VERB
ajlm-1975	16	7	on	on	ADP
ajlm-1975	16	8	a	a	DET
ajlm-1975	16	9	subset	subset	NOUN
ajlm-1975	16	10	of	of	ADP
ajlm-1975	16	11	these	these	DET
ajlm-1975	16	12	isolates	isolate	NOUN
ajlm-1975	16	13	.	.	PUNCT
ajlm-1975	17	1	results	result	NOUN
ajlm-1975	17	2	:	:	PUNCT
ajlm-1975	17	3	out	out	ADP
ajlm-1975	17	4	of	of	ADP
ajlm-1975	17	5	505	505	NUM
ajlm-1975	17	6	patients	patient	NOUN
ajlm-1975	17	7	with	with	ADP
ajlm-1975	17	8	isoniazid	isoniazid	NOUN
ajlm-1975	17	9	mono	mono	NOUN
ajlm-1975	17	10	-	-	PUNCT
ajlm-1975	17	11	resistant	resistant	ADJ
ajlm-1975	17	12	tuberculosis	tuberculosis	NOUN
ajlm-1975	17	13	on	on	ADP
ajlm-1975	17	14	the	the	DET
ajlm-1975	17	15	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	17	16	,	,	PUNCT
ajlm-1975	17	17	145	145	NUM
ajlm-1975	17	18	(	(	PUNCT
ajlm-1975	17	19	28.7	28.7	NUM
ajlm-1975	17	20	%	%	NOUN
ajlm-1975	17	21	)	)	PUNCT
ajlm-1975	17	22	isolates	isolate	NOUN
ajlm-1975	17	23	showed	show	VERB
ajlm-1975	17	24	both	both	DET
ajlm-1975	17	25	isoniazid	isoniazid	NOUN
ajlm-1975	17	26	and	and	CCONJ
ajlm-1975	17	27	rifampicin	rifampicin	VERB
ajlm-1975	17	28	resistance	resistance	NOUN
ajlm-1975	17	29	on	on	ADP
ajlm-1975	17	30	the	the	DET
ajlm-1975	17	31	phenotypic	phenotypic	NOUN
ajlm-1975	17	32	assay	assay	NOUN
ajlm-1975	17	33	.	.	PUNCT
ajlm-1975	18	1	the	the	DET
ajlm-1975	18	2	mean	mean	ADJ
ajlm-1975	18	3	time	time	NOUN
ajlm-1975	18	4	from	from	ADP
ajlm-1975	18	5	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	18	6	results	result	NOUN
ajlm-1975	18	7	to	to	ADP
ajlm-1975	18	8	initiation	initiation	NOUN
ajlm-1975	18	9	of	of	ADP
ajlm-1975	18	10	drug	drug	NOUN
ajlm-1975	18	11	-	-	PUNCT
ajlm-1975	18	12	resistant	resistant	ADJ
ajlm-1975	18	13	tuberculosis	tuberculosis	NOUN
ajlm-1975	18	14	therapy	therapy	NOUN
ajlm-1975	18	15	was	be	AUX
ajlm-1975	18	16	93.7	93.7	NUM
ajlm-1975	18	17	days	day	NOUN
ajlm-1975	18	18	.	.	PUNCT
ajlm-1975	19	1	65.7	65.7	NUM
ajlm-1975	19	2	%	%	NOUN
ajlm-1975	19	3	of	of	ADP
ajlm-1975	19	4	the	the	DET
ajlm-1975	19	5	patients	patient	NOUN
ajlm-1975	19	6	had	have	AUX
ajlm-1975	19	7	received	receive	VERB
ajlm-1975	19	8	previous	previous	ADJ
ajlm-1975	19	9	tuberculosis	tuberculosis	NOUN
ajlm-1975	19	10	treatment	treatment	NOUN
ajlm-1975	19	11	.	.	PUNCT
ajlm-1975	20	1	the	the	DET
ajlm-1975	20	2	most	most	ADV
ajlm-1975	20	3	common	common	ADJ
ajlm-1975	20	4	mutations	mutation	NOUN
ajlm-1975	20	5	detected	detect	VERB
ajlm-1975	20	6	in	in	ADP
ajlm-1975	20	7	the	the	DET
ajlm-1975	20	8	36	36	NUM
ajlm-1975	20	9	sequenced	sequence	VERB
ajlm-1975	20	10	isolates	isolate	NOUN
ajlm-1975	20	11	were	be	AUX
ajlm-1975	20	12	i491f	i491f	PROPN
ajlm-1975	20	13	(	(	PUNCT
ajlm-1975	20	14	16	16	NUM
ajlm-1975	20	15	;	;	PUNCT
ajlm-1975	20	16	44.4	44.4	NUM
ajlm-1975	20	17	%	%	NOUN
ajlm-1975	20	18	)	)	PUNCT
ajlm-1975	20	19	and	and	CCONJ
ajlm-1975	20	20	l452p	l452p	NOUN
ajlm-1975	20	21	(	(	PUNCT
ajlm-1975	20	22	12	12	NUM
ajlm-1975	20	23	;	;	PUNCT
ajlm-1975	20	24	33.3	33.3	NUM
ajlm-1975	20	25	%	%	NOUN
ajlm-1975	20	26	)	)	PUNCT
ajlm-1975	20	27	.	.	PUNCT
ajlm-1975	21	1	among	among	ADP
ajlm-1975	21	2	the	the	DET
ajlm-1975	21	3	36	36	NUM
ajlm-1975	21	4	isolates	isolate	NOUN
ajlm-1975	21	5	,	,	PUNCT
ajlm-1975	21	6	resistance	resistance	NOUN
ajlm-1975	21	7	to	to	ADP
ajlm-1975	21	8	other	other	ADJ
ajlm-1975	21	9	anti	anti	ADJ
ajlm-1975	21	10	-	-	ADJ
ajlm-1975	21	11	tuberculosis	tuberculosis	ADJ
ajlm-1975	21	12	drugs	drug	NOUN
ajlm-1975	21	13	was	be	AUX
ajlm-1975	21	14	69.4	69.4	NUM
ajlm-1975	21	15	%	%	NOUN
ajlm-1975	21	16	for	for	ADP
ajlm-1975	21	17	pyrazinamide	pyrazinamide	NOUN
ajlm-1975	21	18	,	,	PUNCT
ajlm-1975	21	19	83.3	83.3	NUM
ajlm-1975	21	20	%	%	NOUN
ajlm-1975	21	21	for	for	ADP
ajlm-1975	21	22	ethambutol	ethambutol	ADJ
ajlm-1975	21	23	,	,	PUNCT
ajlm-1975	21	24	69.4	69.4	NUM
ajlm-1975	21	25	%	%	NOUN
ajlm-1975	21	26	for	for	ADP
ajlm-1975	21	27	streptomycin	streptomycin	PROPN
ajlm-1975	21	28	,	,	PUNCT
ajlm-1975	21	29	and	and	CCONJ
ajlm-1975	21	30	50	50	NUM
ajlm-1975	21	31	%	%	NOUN
ajlm-1975	21	32	for	for	ADP
ajlm-1975	21	33	ethionamide	ethionamide	NOUN
ajlm-1975	21	34	.	.	PUNCT
ajlm-1975	22	1	conclusion	conclusion	NOUN
ajlm-1975	22	2	:	:	PUNCT
ajlm-1975	22	3	missed	miss	VERB
ajlm-1975	22	4	rifampicin	rifampicin	VERB
ajlm-1975	22	5	resistance	resistance	NOUN
ajlm-1975	22	6	was	be	AUX
ajlm-1975	22	7	mostly	mostly	ADV
ajlm-1975	22	8	due	due	ADJ
ajlm-1975	22	9	to	to	ADP
ajlm-1975	22	10	the	the	DET
ajlm-1975	22	11	i491f	i491f	PROPN
ajlm-1975	22	12	mutation	mutation	NOUN
ajlm-1975	22	13	located	locate	VERB
ajlm-1975	22	14	outside	outside	ADP
ajlm-1975	22	15	the	the	DET
ajlm-1975	22	16	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	22	17	detection	detection	NOUN
ajlm-1975	22	18	area	area	NOUN
ajlm-1975	22	19	and	and	CCONJ
ajlm-1975	22	20	the	the	DET
ajlm-1975	22	21	l452p	l452p	NOUN
ajlm-1975	22	22	mutation	mutation	NOUN
ajlm-1975	22	23	,	,	PUNCT
ajlm-1975	22	24	which	which	PRON
ajlm-1975	22	25	was	be	AUX
ajlm-1975	22	26	not	not	PART
ajlm-1975	22	27	included	include	VERB
ajlm-1975	22	28	in	in	ADP
ajlm-1975	22	29	the	the	DET
ajlm-1975	22	30	initial	initial	ADJ
ajlm-1975	22	31	version	version	NOUN
ajlm-1975	22	32	2	2	NUM
ajlm-1975	22	33	of	of	ADP
ajlm-1975	22	34	the	the	DET
ajlm-1975	22	35	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	22	36	.	.	PUNCT
ajlm-1975	23	1	this	this	PRON
ajlm-1975	23	2	led	lead	VERB
ajlm-1975	23	3	to	to	ADP
ajlm-1975	23	4	substantial	substantial	ADJ
ajlm-1975	23	5	delays	delay	NOUN
ajlm-1975	23	6	in	in	ADP
ajlm-1975	23	7	the	the	DET
ajlm-1975	23	8	initiation	initiation	NOUN
ajlm-1975	23	9	of	of	ADP
ajlm-1975	23	10	appropriate	appropriate	ADJ
ajlm-1975	23	11	therapy	therapy	NOUN
ajlm-1975	23	12	.	.	PUNCT
ajlm-1975	24	1	the	the	DET
ajlm-1975	24	2	previous	previous	ADJ
ajlm-1975	24	3	tuberculosis	tuberculosis	NOUN
ajlm-1975	24	4	treatment	treatment	NOUN
ajlm-1975	24	5	history	history	NOUN
ajlm-1975	24	6	and	and	CCONJ
ajlm-1975	24	7	the	the	DET
ajlm-1975	24	8	high	high	ADJ
ajlm-1975	24	9	level	level	NOUN
ajlm-1975	24	10	of	of	ADP
ajlm-1975	24	11	resistance	resistance	NOUN
ajlm-1975	24	12	to	to	ADP
ajlm-1975	24	13	other	other	ADJ
ajlm-1975	24	14	anti	anti	ADJ
ajlm-1975	24	15	-	-	ADJ
ajlm-1975	24	16	tuberculosis	tuberculosis	ADJ
ajlm-1975	24	17	drugs	drug	NOUN
ajlm-1975	24	18	suggest	suggest	VERB
ajlm-1975	24	19	an	an	DET
ajlm-1975	24	20	accumulation	accumulation	NOUN
ajlm-1975	24	21	of	of	ADP
ajlm-1975	24	22	resistance	resistance	NOUN
ajlm-1975	24	23	.	.	PUNCT
ajlm-1975	25	1	keywords	keyword	NOUN
ajlm-1975	25	2	:	:	PUNCT
ajlm-1975	25	3	tuberculosis	tuberculosis	NOUN
ajlm-1975	25	4	;	;	PUNCT
ajlm-1975	25	5	rifampicin	rifampicin	VERB
ajlm-1975	25	6	resistance	resistance	NOUN
ajlm-1975	25	7	;	;	PUNCT
ajlm-1975	25	8	rpob	rpob	ADJ
ajlm-1975	25	9	mutations	mutation	NOUN
ajlm-1975	25	10	;	;	PUNCT
ajlm-1975	25	11	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	25	12	;	;	PUNCT
ajlm-1975	25	13	discordance	discordance	NOUN
ajlm-1975	25	14	.	.	PUNCT
ajlm-1975	26	1	introduction	introduction	NOUN
ajlm-1975	26	2	access	access	NOUN
ajlm-1975	26	3	to	to	ADP
ajlm-1975	26	4	reliable	reliable	ADJ
ajlm-1975	26	5	,	,	PUNCT
ajlm-1975	26	6	rapid	rapid	ADJ
ajlm-1975	26	7	and	and	CCONJ
ajlm-1975	26	8	automated	automated	ADJ
ajlm-1975	26	9	nucleic	nucleic	ADJ
ajlm-1975	26	10	acid	acid	NOUN
ajlm-1975	26	11	amplification	amplification	NOUN
ajlm-1975	26	12	tests	test	NOUN
ajlm-1975	26	13	remains	remain	VERB
ajlm-1975	26	14	one	one	NUM
ajlm-1975	26	15	of	of	ADP
ajlm-1975	26	16	the	the	DET
ajlm-1975	26	17	key	key	ADJ
ajlm-1975	26	18	factors	factor	NOUN
ajlm-1975	26	19	in	in	ADP
ajlm-1975	26	20	fulfilling	fulfil	VERB
ajlm-1975	26	21	the	the	DET
ajlm-1975	26	22	early	early	ADJ
ajlm-1975	26	23	tuberculosis	tuberculosis	NOUN
ajlm-1975	26	24	diagnosis	diagnosis	NOUN
ajlm-1975	26	25	and	and	CCONJ
ajlm-1975	26	26	universal	universal	ADJ
ajlm-1975	26	27	access	access	NOUN
ajlm-1975	26	28	to	to	ADP
ajlm-1975	26	29	drug	drug	NOUN
ajlm-1975	26	30	susceptibility	susceptibility	NOUN
ajlm-1975	26	31	testing	testing	NOUN
ajlm-1975	26	32	(	(	PUNCT
ajlm-1975	26	33	dst	dst	NOUN
ajlm-1975	26	34	)	)	PUNCT
ajlm-1975	26	35	requirement	requirement	NOUN
ajlm-1975	26	36	of	of	ADP
ajlm-1975	26	37	the	the	DET
ajlm-1975	26	38	world	world	PROPN
ajlm-1975	26	39	health	health	NOUN
ajlm-1975	26	40	organization	organization	NOUN
ajlm-1975	26	41	(	(	PUNCT
ajlm-1975	26	42	who	who	PRON
ajlm-1975	26	43	)	)	PUNCT
ajlm-1975	26	44	end	end	VERB
ajlm-1975	26	45	tb	tb	ADP
ajlm-1975	26	46	strategy.1	strategy.1	NOUN
ajlm-1975	26	47	the	the	DET
ajlm-1975	26	48	past	past	ADJ
ajlm-1975	26	49	decade	decade	NOUN
ajlm-1975	26	50	has	have	AUX
ajlm-1975	26	51	seen	see	VERB
ajlm-1975	26	52	the	the	DET
ajlm-1975	26	53	development	development	NOUN
ajlm-1975	26	54	of	of	ADP
ajlm-1975	26	55	many	many	ADJ
ajlm-1975	26	56	molecular	molecular	ADJ
ajlm-1975	26	57	tests	test	NOUN
ajlm-1975	26	58	,	,	PUNCT
ajlm-1975	26	59	some	some	PRON
ajlm-1975	26	60	of	of	ADP
ajlm-1975	26	61	which	which	PRON
ajlm-1975	26	62	have	have	AUX
ajlm-1975	26	63	been	be	AUX
ajlm-1975	26	64	endorsed	endorse	VERB
ajlm-1975	26	65	by	by	ADP
ajlm-1975	26	66	the	the	DET
ajlm-1975	26	67	who	who	PRON
ajlm-1975	26	68	.	.	PUNCT
ajlm-1975	27	1	the	the	DET
ajlm-1975	27	2	genotype	genotype	NOUN
ajlm-1975	27	3	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	27	4	assay	assay	PROPN
ajlm-1975	27	5	was	be	AUX
ajlm-1975	27	6	the	the	DET
ajlm-1975	27	7	first	first	ADJ
ajlm-1975	27	8	to	to	PART
ajlm-1975	27	9	be	be	AUX
ajlm-1975	27	10	endorsed	endorse	VERB
ajlm-1975	27	11	by	by	ADP
ajlm-1975	27	12	the	the	DET
ajlm-1975	27	13	who	who	PRON
ajlm-1975	27	14	in	in	ADP
ajlm-1975	27	15	2008	2008	NUM
ajlm-1975	27	16	,	,	PUNCT
ajlm-1975	27	17	followed	follow	VERB
ajlm-1975	27	18	by	by	ADP
ajlm-1975	27	19	the	the	DET
ajlm-1975	27	20	xpert	xpert	PROPN
ajlm-1975	27	21	mtb	mtb	PROPN
ajlm-1975	27	22	/	/	SYM
ajlm-1975	27	23	rif	rif	PROPN
ajlm-1975	27	24	(	(	PUNCT
ajlm-1975	27	25	xpert	xpert	PROPN
ajlm-1975	27	26	)	)	PUNCT
ajlm-1975	27	27	in	in	ADP
ajlm-1975	27	28	2010.2,3	2010.2,3	NUM
ajlm-1975	27	29	because	because	SCONJ
ajlm-1975	27	30	of	of	ADP
ajlm-1975	27	31	its	its	PRON
ajlm-1975	27	32	ease	ease	NOUN
ajlm-1975	27	33	of	of	ADP
ajlm-1975	27	34	use	use	NOUN
ajlm-1975	27	35	,	,	PUNCT
ajlm-1975	27	36	the	the	DET
ajlm-1975	27	37	xpert	xpert	PROPN
ajlm-1975	27	38	has	have	AUX
ajlm-1975	27	39	been	be	AUX
ajlm-1975	27	40	implemented	implement	VERB
ajlm-1975	27	41	in	in	ADP
ajlm-1975	27	42	many	many	ADJ
ajlm-1975	27	43	settings	setting	NOUN
ajlm-1975	27	44	for	for	ADP
ajlm-1975	27	45	the	the	DET
ajlm-1975	27	46	initial	initial	ADJ
ajlm-1975	27	47	diagnosis	diagnosis	NOUN
ajlm-1975	27	48	of	of	ADP
ajlm-1975	27	49	tuberculosis	tuberculosis	NOUN
ajlm-1975	27	50	and	and	CCONJ
ajlm-1975	27	51	detection	detection	NOUN
ajlm-1975	27	52	of	of	ADP
ajlm-1975	27	53	rifampicin	rifampicin	VERB
ajlm-1975	27	54	resistance	resistance	NOUN
ajlm-1975	27	55	.	.	PUNCT
ajlm-1975	28	1	both	both	CCONJ
ajlm-1975	28	2	the	the	DET
ajlm-1975	28	3	mtbdrplus	mtbdrplus	NOUN
ajlm-1975	28	4	and	and	CCONJ
ajlm-1975	28	5	the	the	DET
ajlm-1975	28	6	xpert	xpert	PROPN
ajlm-1975	28	7	detect	detect	VERB
ajlm-1975	28	8	rifampicin	rifampicin	VERB
ajlm-1975	28	9	resistance	resistance	NOUN
ajlm-1975	28	10	by	by	ADP
ajlm-1975	28	11	identifying	identify	VERB
ajlm-1975	28	12	mutations	mutation	NOUN
ajlm-1975	28	13	in	in	ADP
ajlm-1975	28	14	the	the	DET
ajlm-1975	28	15	81	81	NUM
ajlm-1975	28	16	-	-	PUNCT
ajlm-1975	28	17	base	base	NOUN
ajlm-1975	28	18	pair	pair	NOUN
ajlm-1975	28	19	region	region	NOUN
ajlm-1975	28	20	of	of	ADP
ajlm-1975	28	21	the	the	DET
ajlm-1975	28	22	rpob	rpob	PROPN
ajlm-1975	28	23	gene	gene	NOUN
ajlm-1975	28	24	,	,	PUNCT
ajlm-1975	28	25	which	which	PRON
ajlm-1975	28	26	spans	span	VERB
ajlm-1975	28	27	codon	codon	ADJ
ajlm-1975	28	28	426–452	426–452	PROPN
ajlm-1975	28	29	in	in	ADP
ajlm-1975	28	30	the	the	DET
ajlm-1975	28	31	mycobacterium	mycobacterium	NOUN
ajlm-1975	28	32	tuberculosis	tuberculosis	NOUN
ajlm-1975	28	33	numbering	numbering	NOUN
ajlm-1975	28	34	system	system	NOUN
ajlm-1975	28	35	and	and	CCONJ
ajlm-1975	28	36	codon	codon	NOUN
ajlm-1975	28	37	507–533	507–533	NUM
ajlm-1975	28	38	in	in	ADP
ajlm-1975	28	39	the	the	DET
ajlm-1975	28	40	escherichia	escherichia	NOUN
ajlm-1975	28	41	coli	coli	NOUN
ajlm-1975	28	42	numbering	number	VERB
ajlm-1975	28	43	system.4	system.4	NOUN
ajlm-1975	28	44	this	this	DET
ajlm-1975	28	45	region	region	NOUN
ajlm-1975	28	46	is	be	AUX
ajlm-1975	28	47	also	also	ADV
ajlm-1975	28	48	called	call	VERB
ajlm-1975	28	49	the	the	DET
ajlm-1975	28	50	rifampicin	rifampicin	VERB
ajlm-1975	28	51	resistance	resistance	NOUN
ajlm-1975	28	52	-	-	PUNCT
ajlm-1975	28	53	determining	determine	VERB
ajlm-1975	28	54	region	region	NOUN
ajlm-1975	28	55	(	(	PUNCT
ajlm-1975	28	56	rrdr	rrdr	PROPN
ajlm-1975	28	57	)	)	PUNCT
ajlm-1975	28	58	,	,	PUNCT
ajlm-1975	28	59	as	as	SCONJ
ajlm-1975	28	60	most	most	ADJ
ajlm-1975	28	61	of	of	ADP
ajlm-1975	28	62	the	the	DET
ajlm-1975	28	63	rifampicin	rifampicin	VERB
ajlm-1975	28	64	resistance	resistance	NOUN
ajlm-1975	28	65	-	-	PUNCT
ajlm-1975	28	66	conferring	confer	VERB
ajlm-1975	28	67	mutations	mutation	NOUN
ajlm-1975	28	68	are	be	AUX
ajlm-1975	28	69	found	find	VERB
ajlm-1975	28	70	in	in	ADP
ajlm-1975	28	71	this	this	DET
ajlm-1975	28	72	region.5	region.5	NOUN
ajlm-1975	28	73	additionally	additionally	ADV
ajlm-1975	28	74	,	,	PUNCT
ajlm-1975	28	75	the	the	DET
ajlm-1975	28	76	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	28	77	also	also	ADV
ajlm-1975	28	78	detects	detect	VERB
ajlm-1975	28	79	resistance	resistance	NOUN
ajlm-1975	28	80	against	against	ADP
ajlm-1975	28	81	isoniazid	isoniazid	NOUN
ajlm-1975	28	82	by	by	ADP
ajlm-1975	28	83	identifying	identify	VERB
ajlm-1975	28	84	mutations	mutation	NOUN
ajlm-1975	28	85	in	in	ADP
ajlm-1975	28	86	the	the	DET
ajlm-1975	28	87	katg	katg	PROPN
ajlm-1975	28	88	gene	gene	NOUN
ajlm-1975	28	89	and	and	CCONJ
ajlm-1975	28	90	the	the	DET
ajlm-1975	28	91	promoter	promoter	NOUN
ajlm-1975	28	92	region	region	NOUN
ajlm-1975	28	93	of	of	ADP
ajlm-1975	28	94	the	the	DET
ajlm-1975	28	95	inha	inha	NOUN
ajlm-1975	28	96	gene	gene	NOUN
ajlm-1975	28	97	.	.	PUNCT
ajlm-1975	29	1	due	due	ADP
ajlm-1975	29	2	to	to	ADP
ajlm-1975	29	3	the	the	DET
ajlm-1975	29	4	limitations	limitation	NOUN
ajlm-1975	29	5	of	of	ADP
ajlm-1975	29	6	the	the	DET
ajlm-1975	29	7	xpert	xpert	PROPN
ajlm-1975	29	8	and	and	CCONJ
ajlm-1975	29	9	the	the	DET
ajlm-1975	29	10	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	29	11	assays	assay	NOUN
ajlm-1975	29	12	,	,	PUNCT
ajlm-1975	29	13	phenotypic	phenotypic	ADJ
ajlm-1975	29	14	methods	method	NOUN
ajlm-1975	29	15	remain	remain	VERB
ajlm-1975	29	16	the	the	DET
ajlm-1975	29	17	gold	gold	ADJ
ajlm-1975	29	18	standard	standard	NOUN
ajlm-1975	29	19	for	for	ADP
ajlm-1975	29	20	tuberculosis	tuberculosis	NOUN
ajlm-1975	29	21	dst	dst	NOUN
ajlm-1975	29	22	.	.	PUNCT
ajlm-1975	30	1	both	both	DET
ajlm-1975	30	2	assays	assay	NOUN
ajlm-1975	30	3	demonstrate	demonstrate	VERB
ajlm-1975	30	4	variable	variable	ADJ
ajlm-1975	30	5	performance	performance	NOUN
ajlm-1975	30	6	in	in	ADP
ajlm-1975	30	7	detecting	detect	VERB
ajlm-1975	30	8	heteroresistance	heteroresistance	NOUN
ajlm-1975	30	9	and	and	CCONJ
ajlm-1975	30	10	do	do	AUX
ajlm-1975	30	11	not	not	PART
ajlm-1975	30	12	detect	detect	VERB
ajlm-1975	30	13	rpob	rpob	ADJ
ajlm-1975	30	14	gene	gene	NOUN
ajlm-1975	30	15	mutations	mutation	NOUN
ajlm-1975	30	16	outside	outside	ADP
ajlm-1975	30	17	the	the	DET
ajlm-1975	30	18	rrdr.6	rrdr.6	NOUN
ajlm-1975	30	19	until	until	ADP
ajlm-1975	30	20	recently	recently	ADV
ajlm-1975	30	21	,	,	PUNCT
ajlm-1975	30	22	mutations	mutation	NOUN
ajlm-1975	30	23	outside	outside	ADP
ajlm-1975	30	24	the	the	DET
ajlm-1975	30	25	rrdr	rrdr	NOUN
ajlm-1975	30	26	were	be	AUX
ajlm-1975	30	27	believed	believe	VERB
ajlm-1975	30	28	to	to	PART
ajlm-1975	30	29	only	only	ADV
ajlm-1975	30	30	account	account	VERB
ajlm-1975	30	31	for	for	ADP
ajlm-1975	30	32	less	less	ADJ
ajlm-1975	30	33	than	than	ADP
ajlm-1975	30	34	5	5	NUM
ajlm-1975	30	35	%	%	NOUN
ajlm-1975	30	36	of	of	ADP
ajlm-1975	30	37	overall	overall	ADJ
ajlm-1975	30	38	rifampicin	rifampicin	VERB
ajlm-1975	30	39	resistance.7,8	resistance.7,8	NOUN
ajlm-1975	30	40	however	however	ADV
ajlm-1975	30	41	,	,	PUNCT
ajlm-1975	30	42	in	in	ADP
ajlm-1975	30	43	a	a	DET
ajlm-1975	30	44	national	national	ADJ
ajlm-1975	30	45	drug	drug	NOUN
ajlm-1975	30	46	resistance	resistance	NOUN
ajlm-1975	30	47	survey	survey	NOUN
ajlm-1975	30	48	conducted	conduct	VERB
ajlm-1975	30	49	in	in	ADP
ajlm-1975	30	50	eswatini	eswatini	NOUN
ajlm-1975	30	51	between	between	ADP
ajlm-1975	30	52	2009	2009	NUM
ajlm-1975	30	53	and	and	CCONJ
ajlm-1975	30	54	2010	2010	NUM
ajlm-1975	30	55	,	,	PUNCT
ajlm-1975	30	56	30	30	NUM
ajlm-1975	30	57	%	%	NOUN
ajlm-1975	30	58	of	of	ADP
ajlm-1975	30	59	multidrug	multidrug	NOUN
ajlm-1975	30	60	-	-	PUNCT
ajlm-1975	30	61	resistant	resistant	ADJ
ajlm-1975	30	62	tuberculosis	tuberculosis	NOUN
ajlm-1975	30	63	(	(	PUNCT
ajlm-1975	30	64	mdr	mdr	PROPN
ajlm-1975	30	65	-	-	NOUN
ajlm-1975	30	66	tb	tb	NOUN
ajlm-1975	30	67	:	:	PUNCT
ajlm-1975	30	68	resistant	resistant	ADJ
ajlm-1975	30	69	to	to	ADP
ajlm-1975	30	70	rifampicin	rifampicin	VERB
ajlm-1975	30	71	and	and	CCONJ
ajlm-1975	30	72	isoniazid	isoniazid	NOUN
ajlm-1975	30	73	)	)	PUNCT
ajlm-1975	30	74	isolates	isolate	NOUN
ajlm-1975	30	75	carried	carry	VERB
ajlm-1975	30	76	the	the	DET
ajlm-1975	30	77	i491f	i491f	PROPN
ajlm-1975	30	78	rpob	rpob	PROPN
ajlm-1975	30	79	gene	gene	NOUN
ajlm-1975	30	80	mutation	mutation	NOUN
ajlm-1975	30	81	located	locate	VERB
ajlm-1975	30	82	outside	outside	ADP
ajlm-1975	30	83	the	the	DET
ajlm-1975	30	84	rrdr.9	rrdr.9	PROPN
ajlm-1975	30	85	this	this	PRON
ajlm-1975	30	86	caused	cause	VERB
ajlm-1975	30	87	concerns	concern	NOUN
ajlm-1975	30	88	,	,	PUNCT
ajlm-1975	30	89	especially	especially	ADV
ajlm-1975	30	90	in	in	ADP
ajlm-1975	30	91	neighbouring	neighbouring	ADJ
ajlm-1975	30	92	countries	country	NOUN
ajlm-1975	30	93	like	like	ADP
ajlm-1975	30	94	south	south	PROPN
ajlm-1975	30	95	africa	africa	PROPN
ajlm-1975	30	96	,	,	PUNCT
ajlm-1975	30	97	because	because	SCONJ
ajlm-1975	30	98	while	while	SCONJ
ajlm-1975	30	99	this	this	DET
ajlm-1975	30	100	mutation	mutation	NOUN
ajlm-1975	30	101	is	be	AUX
ajlm-1975	30	102	rare	rare	ADJ
ajlm-1975	30	103	globally	globally	ADV
ajlm-1975	30	104	,	,	PUNCT
ajlm-1975	30	105	it	it	PRON
ajlm-1975	30	106	might	might	AUX
ajlm-1975	30	107	be	be	AUX
ajlm-1975	30	108	more	more	ADV
ajlm-1975	30	109	common	common	ADJ
ajlm-1975	30	110	in	in	ADP
ajlm-1975	30	111	certain	certain	ADJ
ajlm-1975	30	112	geographical	geographical	ADJ
ajlm-1975	30	113	settings	setting	NOUN
ajlm-1975	30	114	.	.	PUNCT
ajlm-1975	31	1	a	a	DET
ajlm-1975	31	2	subsequent	subsequent	ADJ
ajlm-1975	31	3	study	study	NOUN
ajlm-1975	31	4	conducted	conduct	VERB
ajlm-1975	31	5	in	in	ADP
ajlm-1975	31	6	the	the	DET
ajlm-1975	31	7	northern	northern	ADJ
ajlm-1975	31	8	provinces	province	NOUN
ajlm-1975	31	9	of	of	ADP
ajlm-1975	31	10	south	south	PROPN
ajlm-1975	31	11	africa	africa	PROPN
ajlm-1975	31	12	showed	show	VERB
ajlm-1975	31	13	that	that	SCONJ
ajlm-1975	31	14	15	15	NUM
ajlm-1975	31	15	%	%	NOUN
ajlm-1975	31	16	of	of	ADP
ajlm-1975	31	17	isoniazid	isoniazid	NOUN
ajlm-1975	31	18	mono	mono	NOUN
ajlm-1975	31	19	-	-	PUNCT
ajlm-1975	31	20	resistant	resistant	ADJ
ajlm-1975	31	21	strains	strain	NOUN
ajlm-1975	31	22	carried	carry	VERB
ajlm-1975	31	23	the	the	DET
ajlm-1975	31	24	i491	i491	PROPN
ajlm-1975	31	25	mutation	mutation	NOUN
ajlm-1975	31	26	,	,	PUNCT
ajlm-1975	31	27	meaning	mean	VERB
ajlm-1975	31	28	they	they	PRON
ajlm-1975	31	29	were	be	AUX
ajlm-1975	31	30	mdr	mdr	PROPN
ajlm-1975	31	31	-	-	PROPN
ajlm-1975	31	32	tb	tb	ADP
ajlm-1975	31	33	strains.10	strains.10	NOUN
ajlm-1975	31	34	the	the	DET
ajlm-1975	31	35	same	same	ADJ
ajlm-1975	31	36	study	study	NOUN
ajlm-1975	31	37	also	also	ADV
ajlm-1975	31	38	revealed	reveal	VERB
ajlm-1975	31	39	that	that	SCONJ
ajlm-1975	31	40	strains	strain	NOUN
ajlm-1975	31	41	carrying	carry	VERB
ajlm-1975	31	42	this	this	DET
ajlm-1975	31	43	mutation	mutation	NOUN
ajlm-1975	31	44	may	may	AUX
ajlm-1975	31	45	be	be	AUX
ajlm-1975	31	46	driving	drive	VERB
ajlm-1975	31	47	outbreaks	outbreak	NOUN
ajlm-1975	31	48	of	of	ADP
ajlm-1975	31	49	mdr	mdr	PROPN
ajlm-1975	31	50	-	-	NOUN
ajlm-1975	31	51	tb	tb	NOUN
ajlm-1975	31	52	in	in	ADP
ajlm-1975	31	53	eswatini	eswatini	PROPN
ajlm-1975	31	54	and	and	CCONJ
ajlm-1975	31	55	south	south	ADJ
ajlm-1975	31	56	africa.10	africa.10	ADJ
ajlm-1975	31	57	rapid	rapid	ADJ
ajlm-1975	31	58	molecular	molecular	ADJ
ajlm-1975	31	59	tests	test	NOUN
ajlm-1975	31	60	that	that	PRON
ajlm-1975	31	61	only	only	ADV
ajlm-1975	31	62	detect	detect	VERB
ajlm-1975	31	63	mutations	mutation	NOUN
ajlm-1975	31	64	in	in	ADP
ajlm-1975	31	65	the	the	DET
ajlm-1975	31	66	rrdr	rrdr	NOUN
ajlm-1975	31	67	may	may	AUX
ajlm-1975	31	68	fail	fail	VERB
ajlm-1975	31	69	to	to	PART
ajlm-1975	31	70	detect	detect	VERB
ajlm-1975	31	71	rifampicin	rifampicin	VERB
ajlm-1975	31	72	resistance	resistance	NOUN
ajlm-1975	31	73	in	in	ADP
ajlm-1975	31	74	patients	patient	NOUN
ajlm-1975	31	75	with	with	ADP
ajlm-1975	31	76	tuberculosis	tuberculosis	NOUN
ajlm-1975	31	77	caused	cause	VERB
ajlm-1975	31	78	by	by	ADP
ajlm-1975	31	79	strains	strain	NOUN
ajlm-1975	31	80	carrying	carry	VERB
ajlm-1975	31	81	mutations	mutation	NOUN
ajlm-1975	31	82	outside	outside	ADP
ajlm-1975	31	83	the	the	DET
ajlm-1975	31	84	rrdr	rrdr	NOUN
ajlm-1975	31	85	,	,	PUNCT
ajlm-1975	31	86	and	and	CCONJ
ajlm-1975	31	87	this	this	PRON
ajlm-1975	31	88	may	may	AUX
ajlm-1975	31	89	lead	lead	VERB
ajlm-1975	31	90	to	to	ADP
ajlm-1975	31	91	inappropriate	inappropriate	ADJ
ajlm-1975	31	92	management	management	NOUN
ajlm-1975	31	93	,	,	PUNCT
ajlm-1975	31	94	resulting	result	VERB
ajlm-1975	31	95	in	in	ADP
ajlm-1975	31	96	resistance	resistance	NOUN
ajlm-1975	31	97	selection	selection	NOUN
ajlm-1975	31	98	,	,	PUNCT
ajlm-1975	31	99	accumulation	accumulation	NOUN
ajlm-1975	31	100	of	of	ADP
ajlm-1975	31	101	resistance	resistance	NOUN
ajlm-1975	31	102	,	,	PUNCT
ajlm-1975	31	103	treatment	treatment	NOUN
ajlm-1975	31	104	failure	failure	NOUN
ajlm-1975	31	105	and	and	CCONJ
ajlm-1975	31	106	increased	increase	VERB
ajlm-1975	31	107	transmission	transmission	NOUN
ajlm-1975	31	108	.	.	PUNCT
ajlm-1975	32	1	in	in	ADP
ajlm-1975	32	2	settings	setting	NOUN
ajlm-1975	32	3	where	where	SCONJ
ajlm-1975	32	4	molecular	molecular	ADJ
ajlm-1975	32	5	and	and	CCONJ
ajlm-1975	32	6	phenotypic	phenotypic	ADJ
ajlm-1975	32	7	rifampicin	rifampicin	VERB
ajlm-1975	32	8	dst	dst	NOUN
ajlm-1975	32	9	are	be	AUX
ajlm-1975	32	10	performed	perform	VERB
ajlm-1975	32	11	concurrently	concurrently	ADV
ajlm-1975	32	12	,	,	PUNCT
ajlm-1975	32	13	discordant	discordant	ADJ
ajlm-1975	32	14	results	result	NOUN
ajlm-1975	32	15	often	often	ADV
ajlm-1975	32	16	occur	occur	VERB
ajlm-1975	32	17	,	,	PUNCT
ajlm-1975	32	18	especially	especially	ADV
ajlm-1975	32	19	with	with	ADP
ajlm-1975	32	20	liquid	liquid	ADJ
ajlm-1975	32	21	culture	culture	NOUN
ajlm-1975	32	22	-	-	PUNCT
ajlm-1975	32	23	based	base	VERB
ajlm-1975	32	24	assays.11,12	assays.11,12	NOUN
ajlm-1975	32	25	given	give	VERB
ajlm-1975	32	26	the	the	DET
ajlm-1975	32	27	fact	fact	NOUN
ajlm-1975	32	28	that	that	SCONJ
ajlm-1975	32	29	rifampicin	rifampicin	VERB
ajlm-1975	32	30	is	be	AUX
ajlm-1975	32	31	the	the	DET
ajlm-1975	32	32	key	key	ADJ
ajlm-1975	32	33	determinant	determinant	NOUN
ajlm-1975	32	34	of	of	ADP
ajlm-1975	32	35	the	the	DET
ajlm-1975	32	36	choice	choice	NOUN
ajlm-1975	32	37	of	of	ADP
ajlm-1975	32	38	a	a	DET
ajlm-1975	32	39	treatment	treatment	NOUN
ajlm-1975	32	40	regimen	regiman	NOUN
ajlm-1975	32	41	,	,	PUNCT
ajlm-1975	32	42	the	the	DET
ajlm-1975	32	43	hesitancy	hesitancy	NOUN
ajlm-1975	32	44	caused	cause	VERB
ajlm-1975	32	45	by	by	ADP
ajlm-1975	32	46	discordant	discordant	ADJ
ajlm-1975	32	47	results	result	NOUN
ajlm-1975	32	48	may	may	AUX
ajlm-1975	32	49	also	also	ADV
ajlm-1975	32	50	affect	affect	VERB
ajlm-1975	32	51	the	the	DET
ajlm-1975	32	52	decision	decision	NOUN
ajlm-1975	32	53	to	to	PART
ajlm-1975	32	54	start	start	VERB
ajlm-1975	32	55	appropriate	appropriate	ADJ
ajlm-1975	32	56	treatment	treatment	NOUN
ajlm-1975	32	57	in	in	ADP
ajlm-1975	32	58	the	the	DET
ajlm-1975	32	59	affected	affected	ADJ
ajlm-1975	32	60	patients	patient	NOUN
ajlm-1975	32	61	.	.	PUNCT
ajlm-1975	33	1	often	often	ADV
ajlm-1975	33	2	,	,	PUNCT
ajlm-1975	33	3	an	an	DET
ajlm-1975	33	4	attempt	attempt	NOUN
ajlm-1975	33	5	is	be	AUX
ajlm-1975	33	6	made	make	VERB
ajlm-1975	33	7	to	to	PART
ajlm-1975	33	8	confirm	confirm	VERB
ajlm-1975	33	9	a	a	DET
ajlm-1975	33	10	discordant	discordant	ADJ
ajlm-1975	33	11	result	result	NOUN
ajlm-1975	33	12	by	by	ADP
ajlm-1975	33	13	either	either	CCONJ
ajlm-1975	33	14	repeating	repeat	VERB
ajlm-1975	33	15	the	the	DET
ajlm-1975	33	16	test	test	NOUN
ajlm-1975	33	17	or	or	CCONJ
ajlm-1975	33	18	using	use	VERB
ajlm-1975	33	19	another	another	DET
ajlm-1975	33	20	confirmatory	confirmatory	NOUN
ajlm-1975	33	21	assay	assay	NOUN
ajlm-1975	33	22	(	(	PUNCT
ajlm-1975	33	23	if	if	SCONJ
ajlm-1975	33	24	available	available	ADJ
ajlm-1975	33	25	)	)	PUNCT
ajlm-1975	33	26	,	,	PUNCT
ajlm-1975	33	27	thus	thus	ADV
ajlm-1975	33	28	causing	cause	VERB
ajlm-1975	33	29	further	further	ADJ
ajlm-1975	33	30	delay	delay	NOUN
ajlm-1975	33	31	in	in	ADP
ajlm-1975	33	32	initiating	initiate	VERB
ajlm-1975	33	33	appropriate	appropriate	ADJ
ajlm-1975	33	34	therapy	therapy	NOUN
ajlm-1975	33	35	.	.	PUNCT
ajlm-1975	34	1	because	because	SCONJ
ajlm-1975	34	2	the	the	DET
ajlm-1975	34	3	kwazulu	kwazulu	VERB
ajlm-1975	34	4	-	-	PUNCT
ajlm-1975	34	5	natal	natal	ADJ
ajlm-1975	34	6	province	province	NOUN
ajlm-1975	34	7	accounts	account	VERB
ajlm-1975	34	8	for	for	ADP
ajlm-1975	34	9	almost	almost	ADV
ajlm-1975	34	10	30	30	NUM
ajlm-1975	34	11	%	%	NOUN
ajlm-1975	34	12	of	of	ADP
ajlm-1975	34	13	south	south	PROPN
ajlm-1975	34	14	africa	africa	PROPN
ajlm-1975	34	15	’s	’s	PART
ajlm-1975	34	16	drug	drug	NOUN
ajlm-1975	34	17	-	-	PUNCT
ajlm-1975	34	18	resistant	resistant	ADJ
ajlm-1975	34	19	tuberculosis	tuberculosis	NOUN
ajlm-1975	34	20	(	(	PUNCT
ajlm-1975	34	21	dr	dr	NOUN
ajlm-1975	34	22	-	-	PUNCT
ajlm-1975	34	23	tb	tb	NOUN
ajlm-1975	34	24	)	)	PUNCT
ajlm-1975	34	25	cases	case	NOUN
ajlm-1975	34	26	,	,	PUNCT
ajlm-1975	34	27	and	and	CCONJ
ajlm-1975	34	28	since	since	SCONJ
ajlm-1975	34	29	eswatini	eswatini	NOUN
ajlm-1975	34	30	forms	form	NOUN
ajlm-1975	34	31	part	part	NOUN
ajlm-1975	34	32	of	of	ADP
ajlm-1975	34	33	its	its	PRON
ajlm-1975	34	34	northern	northern	ADJ
ajlm-1975	34	35	border	border	NOUN
ajlm-1975	34	36	,	,	PUNCT
ajlm-1975	34	37	we	we	PRON
ajlm-1975	34	38	conducted	conduct	VERB
ajlm-1975	34	39	this	this	DET
ajlm-1975	34	40	study	study	NOUN
ajlm-1975	34	41	in	in	ADP
ajlm-1975	34	42	kwazulu	kwazulu	PROPN
ajlm-1975	34	43	-	-	PUNCT
ajlm-1975	34	44	natal	natal	ADJ
ajlm-1975	34	45	,	,	PUNCT
ajlm-1975	34	46	south	south	PROPN
ajlm-1975	34	47	africa	africa	PROPN
ajlm-1975	34	48	,	,	PUNCT
ajlm-1975	34	49	to	to	PART
ajlm-1975	34	50	determine	determine	VERB
ajlm-1975	34	51	why	why	SCONJ
ajlm-1975	34	52	phenotypically	phenotypically	ADV
ajlm-1975	34	53	resistant	resistant	ADJ
ajlm-1975	34	54	isolates	isolate	NOUN
ajlm-1975	34	55	were	be	AUX
ajlm-1975	34	56	reported	report	VERB
ajlm-1975	34	57	as	as	SCONJ
ajlm-1975	34	58	rifampicin	rifampicin	VERB
ajlm-1975	34	59	susceptible	susceptible	ADJ
ajlm-1975	34	60	on	on	ADP
ajlm-1975	34	61	the	the	DET
ajlm-1975	34	62	mtbdrplus.13	mtbdrplus.13	PROPN
ajlm-1975	34	63	considering	consider	VERB
ajlm-1975	34	64	the	the	DET
ajlm-1975	34	65	dearth	dearth	NOUN
ajlm-1975	34	66	of	of	ADP
ajlm-1975	34	67	information	information	NOUN
ajlm-1975	34	68	on	on	ADP
ajlm-1975	34	69	the	the	DET
ajlm-1975	34	70	clinical	clinical	ADJ
ajlm-1975	34	71	management	management	NOUN
ajlm-1975	34	72	of	of	ADP
ajlm-1975	34	73	patients	patient	NOUN
ajlm-1975	34	74	with	with	ADP
ajlm-1975	34	75	rifampicin	rifampicin	VERB
ajlm-1975	34	76	-	-	PUNCT
ajlm-1975	34	77	discordant	discordant	ADJ
ajlm-1975	34	78	tuberculosis	tuberculosis	NOUN
ajlm-1975	34	79	results	result	NOUN
ajlm-1975	34	80	globally	globally	ADV
ajlm-1975	34	81	,	,	PUNCT
ajlm-1975	34	82	we	we	PRON
ajlm-1975	34	83	also	also	ADV
ajlm-1975	34	84	report	report	VERB
ajlm-1975	34	85	on	on	ADP
ajlm-1975	34	86	the	the	DET
ajlm-1975	34	87	programmatic	programmatic	ADJ
ajlm-1975	34	88	management	management	NOUN
ajlm-1975	34	89	of	of	ADP
ajlm-1975	34	90	these	these	DET
ajlm-1975	34	91	patients	patient	NOUN
ajlm-1975	34	92	in	in	ADP
ajlm-1975	34	93	our	our	PRON
ajlm-1975	34	94	setting	setting	NOUN
ajlm-1975	34	95	.	.	PUNCT
ajlm-1975	35	1	methods	method	NOUN
ajlm-1975	35	2	ethical	ethical	ADJ
ajlm-1975	35	3	considerations	consideration	NOUN
ajlm-1975	35	4	ethics	ethic	NOUN
ajlm-1975	35	5	approval	approval	NOUN
ajlm-1975	35	6	was	be	AUX
ajlm-1975	35	7	obtained	obtain	VERB
ajlm-1975	35	8	from	from	ADP
ajlm-1975	35	9	the	the	DET
ajlm-1975	35	10	university	university	NOUN
ajlm-1975	35	11	of	of	ADP
ajlm-1975	35	12	kwazulu	kwazulu	PROPN
ajlm-1975	35	13	-	-	PUNCT
ajlm-1975	35	14	natal	natal	ADJ
ajlm-1975	35	15	biomedical	biomedical	ADJ
ajlm-1975	35	16	research	research	NOUN
ajlm-1975	35	17	ethics	ethic	NOUN
ajlm-1975	35	18	council	council	PROPN
ajlm-1975	35	19	(	(	PUNCT
ajlm-1975	35	20	be267/18	be267/18	PROPN
ajlm-1975	35	21	)	)	PUNCT
ajlm-1975	35	22	.	.	PUNCT
ajlm-1975	36	1	individual	individual	ADJ
ajlm-1975	36	2	patient	patient	ADJ
ajlm-1975	36	3	consent	consent	NOUN
ajlm-1975	36	4	was	be	AUX
ajlm-1975	36	5	not	not	PART
ajlm-1975	36	6	required	require	VERB
ajlm-1975	36	7	as	as	SCONJ
ajlm-1975	36	8	only	only	ADV
ajlm-1975	36	9	routine	routine	ADJ
ajlm-1975	36	10	programmatic	programmatic	ADJ
ajlm-1975	36	11	data	datum	NOUN
ajlm-1975	36	12	was	be	AUX
ajlm-1975	36	13	accessed	access	VERB
ajlm-1975	36	14	;	;	PUNCT
ajlm-1975	36	15	however	however	ADV
ajlm-1975	36	16	,	,	PUNCT
ajlm-1975	36	17	permission	permission	NOUN
ajlm-1975	36	18	was	be	AUX
ajlm-1975	36	19	obtained	obtain	VERB
ajlm-1975	36	20	from	from	ADP
ajlm-1975	36	21	the	the	DET
ajlm-1975	36	22	provincial	provincial	ADJ
ajlm-1975	36	23	department	department	NOUN
ajlm-1975	36	24	of	of	ADP
ajlm-1975	36	25	health	health	NOUN
ajlm-1975	36	26	.	.	PUNCT
ajlm-1975	37	1	for	for	ADP
ajlm-1975	37	2	anonymity	anonymity	NOUN
ajlm-1975	37	3	,	,	PUNCT
ajlm-1975	37	4	patients	patient	NOUN
ajlm-1975	37	5	’	'	PUNCT
ajlm-1975	37	6	names	name	NOUN
ajlm-1975	37	7	were	be	AUX
ajlm-1975	37	8	only	only	ADV
ajlm-1975	37	9	used	use	VERB
ajlm-1975	37	10	for	for	ADP
ajlm-1975	37	11	data	data	NOUN
ajlm-1975	37	12	collection	collection	NOUN
ajlm-1975	37	13	and	and	CCONJ
ajlm-1975	37	14	were	be	AUX
ajlm-1975	37	15	not	not	PART
ajlm-1975	37	16	used	use	VERB
ajlm-1975	37	17	during	during	ADP
ajlm-1975	37	18	analysis	analysis	NOUN
ajlm-1975	37	19	.	.	PUNCT
ajlm-1975	38	1	study	study	NOUN
ajlm-1975	38	2	design	design	NOUN
ajlm-1975	38	3	and	and	CCONJ
ajlm-1975	38	4	setting	set	VERB
ajlm-1975	38	5	the	the	DET
ajlm-1975	38	6	study	study	NOUN
ajlm-1975	38	7	was	be	AUX
ajlm-1975	38	8	conducted	conduct	VERB
ajlm-1975	38	9	in	in	ADP
ajlm-1975	38	10	the	the	DET
ajlm-1975	38	11	kwazulu	kwazulu	VERB
ajlm-1975	38	12	-	-	PUNCT
ajlm-1975	38	13	natal	natal	ADJ
ajlm-1975	38	14	province	province	NOUN
ajlm-1975	38	15	in	in	ADP
ajlm-1975	38	16	south	south	PROPN
ajlm-1975	38	17	africa	africa	PROPN
ajlm-1975	38	18	.	.	PUNCT
ajlm-1975	39	1	the	the	DET
ajlm-1975	39	2	province	province	NOUN
ajlm-1975	39	3	has	have	VERB
ajlm-1975	39	4	the	the	DET
ajlm-1975	39	5	second	second	ADV
ajlm-1975	39	6	-	-	PUNCT
ajlm-1975	39	7	highest	high	ADJ
ajlm-1975	39	8	population	population	NOUN
ajlm-1975	39	9	in	in	ADP
ajlm-1975	39	10	the	the	DET
ajlm-1975	39	11	country	country	NOUN
ajlm-1975	39	12	with	with	ADP
ajlm-1975	39	13	more	more	ADJ
ajlm-1975	39	14	than	than	ADP
ajlm-1975	39	15	11	11	NUM
ajlm-1975	39	16	million	million	NUM
ajlm-1975	39	17	people	people	NOUN
ajlm-1975	39	18	.	.	PUNCT
ajlm-1975	40	1	there	there	PRON
ajlm-1975	40	2	are	be	VERB
ajlm-1975	40	3	11	11	NUM
ajlm-1975	40	4	districts	district	NOUN
ajlm-1975	40	5	in	in	ADP
ajlm-1975	40	6	the	the	DET
ajlm-1975	40	7	province	province	NOUN
ajlm-1975	40	8	and	and	CCONJ
ajlm-1975	40	9	one	one	NUM
ajlm-1975	40	10	mdr	mdr	NOUN
ajlm-1975	40	11	-	-	NOUN
ajlm-1975	40	12	tb	tb	ADP
ajlm-1975	40	13	treatment	treatment	NOUN
ajlm-1975	40	14	facility	facility	NOUN
ajlm-1975	40	15	per	per	ADP
ajlm-1975	40	16	district	district	NOUN
ajlm-1975	40	17	.	.	PUNCT
ajlm-1975	41	1	in	in	ADP
ajlm-1975	41	2	health	health	NOUN
ajlm-1975	41	3	facilities	facility	NOUN
ajlm-1975	41	4	in	in	ADP
ajlm-1975	41	5	the	the	DET
ajlm-1975	41	6	kwazulu	kwazulu	ADJ
ajlm-1975	41	7	-	-	PUNCT
ajlm-1975	41	8	natal	natal	NOUN
ajlm-1975	41	9	province	province	NOUN
ajlm-1975	41	10	,	,	PUNCT
ajlm-1975	41	11	the	the	DET
ajlm-1975	41	12	initial	initial	ADJ
ajlm-1975	41	13	diagnosis	diagnosis	NOUN
ajlm-1975	41	14	of	of	ADP
ajlm-1975	41	15	tuberculosis	tuberculosis	NOUN
ajlm-1975	41	16	and	and	CCONJ
ajlm-1975	41	17	rifampicin	rifampicin	VERB
ajlm-1975	41	18	resistance	resistance	NOUN
ajlm-1975	41	19	is	be	AUX
ajlm-1975	41	20	routinely	routinely	ADV
ajlm-1975	41	21	done	do	VERB
ajlm-1975	41	22	using	use	VERB
ajlm-1975	41	23	the	the	DET
ajlm-1975	41	24	xpert	xpert	PROPN
ajlm-1975	41	25	(	(	PUNCT
ajlm-1975	41	26	xpert	xpert	PROPN
ajlm-1975	41	27	mtb	mtb	PROPN
ajlm-1975	41	28	/	/	SYM
ajlm-1975	41	29	rif	rif	PROPN
ajlm-1975	41	30	,	,	PUNCT
ajlm-1975	41	31	cepheid	cepheid	PROPN
ajlm-1975	41	32	,	,	PUNCT
ajlm-1975	41	33	sunnyvale	sunnyvale	PROPN
ajlm-1975	41	34	,	,	PUNCT
ajlm-1975	41	35	california	california	PROPN
ajlm-1975	41	36	,	,	PUNCT
ajlm-1975	41	37	united	united	PROPN
ajlm-1975	41	38	states	states	PROPN
ajlm-1975	41	39	)	)	PUNCT
ajlm-1975	41	40	in	in	ADP
ajlm-1975	41	41	all	all	DET
ajlm-1975	41	42	patients	patient	NOUN
ajlm-1975	41	43	suspected	suspect	VERB
ajlm-1975	41	44	of	of	ADP
ajlm-1975	41	45	tuberculosis	tuberculosis	NUM
ajlm-1975	41	46	disease	disease	NOUN
ajlm-1975	41	47	.	.	PUNCT
ajlm-1975	42	1	the	the	DET
ajlm-1975	42	2	xpert	xpert	PROPN
ajlm-1975	42	3	was	be	AUX
ajlm-1975	42	4	previously	previously	ADV
ajlm-1975	42	5	used	use	VERB
ajlm-1975	42	6	but	but	CCONJ
ajlm-1975	42	7	was	be	AUX
ajlm-1975	42	8	later	later	ADV
ajlm-1975	42	9	replaced	replace	VERB
ajlm-1975	42	10	by	by	ADP
ajlm-1975	42	11	its	its	PRON
ajlm-1975	42	12	successor	successor	NOUN
ajlm-1975	42	13	,	,	PUNCT
ajlm-1975	42	14	the	the	DET
ajlm-1975	42	15	xpert	xpert	PROPN
ajlm-1975	42	16	mtb	mtb	PROPN
ajlm-1975	42	17	/	/	SYM
ajlm-1975	42	18	rif	rif	PROPN
ajlm-1975	42	19	ultra	ultra	PROPN
ajlm-1975	42	20	(	(	PUNCT
ajlm-1975	42	21	xpert	xpert	PROPN
ajlm-1975	42	22	ultra	ultra	PROPN
ajlm-1975	42	23	,	,	PUNCT
ajlm-1975	42	24	cepheid	cepheid	NOUN
ajlm-1975	42	25	,	,	PUNCT
ajlm-1975	42	26	sunnyvale	sunnyvale	PROPN
ajlm-1975	42	27	,	,	PUNCT
ajlm-1975	42	28	california	california	PROPN
ajlm-1975	42	29	,	,	PUNCT
ajlm-1975	42	30	united	united	PROPN
ajlm-1975	42	31	states	states	PROPN
ajlm-1975	42	32	)	)	PUNCT
ajlm-1975	42	33	,	,	PUNCT
ajlm-1975	42	34	in	in	ADP
ajlm-1975	42	35	2017	2017	NUM
ajlm-1975	42	36	.	.	PUNCT
ajlm-1975	43	1	for	for	ADP
ajlm-1975	43	2	patients	patient	NOUN
ajlm-1975	43	3	with	with	ADP
ajlm-1975	43	4	rifampicin	rifampicin	VERB
ajlm-1975	43	5	-	-	PUNCT
ajlm-1975	43	6	susceptible	susceptible	ADJ
ajlm-1975	43	7	tuberculosis	tuberculosis	NOUN
ajlm-1975	43	8	,	,	PUNCT
ajlm-1975	43	9	no	no	PRON
ajlm-1975	43	10	further	far	ADV
ajlm-1975	43	11	dst	dst	NOUN
ajlm-1975	43	12	is	be	AUX
ajlm-1975	43	13	performed	perform	VERB
ajlm-1975	43	14	,	,	PUNCT
ajlm-1975	43	15	and	and	CCONJ
ajlm-1975	43	16	they	they	PRON
ajlm-1975	43	17	are	be	AUX
ajlm-1975	43	18	treated	treat	VERB
ajlm-1975	43	19	using	use	VERB
ajlm-1975	43	20	first	first	ADJ
ajlm-1975	43	21	-	-	PUNCT
ajlm-1975	43	22	line	line	NOUN
ajlm-1975	43	23	tuberculosis	tuberculosis	NOUN
ajlm-1975	43	24	therapy	therapy	NOUN
ajlm-1975	43	25	.	.	PUNCT
ajlm-1975	44	1	in	in	ADP
ajlm-1975	44	2	patients	patient	NOUN
ajlm-1975	44	3	with	with	ADP
ajlm-1975	44	4	rifampicin	rifampicin	NOUN
ajlm-1975	44	5	-	-	PUNCT
ajlm-1975	44	6	resistant	resistant	ADJ
ajlm-1975	44	7	tuberculosis	tuberculosis	NOUN
ajlm-1975	44	8	on	on	ADP
ajlm-1975	44	9	the	the	DET
ajlm-1975	44	10	xpert	xpert	PROPN
ajlm-1975	44	11	(	(	PUNCT
ajlm-1975	44	12	ultra	ultra	ADJ
ajlm-1975	44	13	)	)	PUNCT
ajlm-1975	44	14	,	,	PUNCT
ajlm-1975	44	15	a	a	DET
ajlm-1975	44	16	second	second	ADJ
ajlm-1975	44	17	sample	sample	NOUN
ajlm-1975	44	18	is	be	AUX
ajlm-1975	44	19	taken	take	VERB
ajlm-1975	44	20	for	for	ADP
ajlm-1975	44	21	culture	culture	NOUN
ajlm-1975	44	22	and	and	CCONJ
ajlm-1975	44	23	dst	dst	PROPN
ajlm-1975	44	24	.	.	PUNCT
ajlm-1975	45	1	other	other	ADJ
ajlm-1975	45	2	indications	indication	NOUN
ajlm-1975	45	3	for	for	ADP
ajlm-1975	45	4	tuberculosis	tuberculosis	NOUN
ajlm-1975	45	5	culture	culture	NOUN
ajlm-1975	45	6	include	include	VERB
ajlm-1975	45	7	treatment	treatment	NOUN
ajlm-1975	45	8	failure	failure	NOUN
ajlm-1975	45	9	and	and	CCONJ
ajlm-1975	45	10	paucibacillary	paucibacillary	ADJ
ajlm-1975	45	11	tuberculosis	tuberculosis	NOUN
ajlm-1975	45	12	that	that	PRON
ajlm-1975	45	13	shows	show	VERB
ajlm-1975	45	14	a	a	DET
ajlm-1975	45	15	negative	negative	ADJ
ajlm-1975	45	16	result	result	NOUN
ajlm-1975	45	17	on	on	ADP
ajlm-1975	45	18	the	the	DET
ajlm-1975	45	19	xpert	xpert	PROPN
ajlm-1975	45	20	(	(	PUNCT
ajlm-1975	45	21	ultra	ultra	ADJ
ajlm-1975	45	22	)	)	PUNCT
ajlm-1975	45	23	.	.	PUNCT
ajlm-1975	46	1	during	during	ADP
ajlm-1975	46	2	the	the	DET
ajlm-1975	46	3	study	study	NOUN
ajlm-1975	46	4	period	period	NOUN
ajlm-1975	46	5	between	between	ADP
ajlm-1975	46	6	january	january	PROPN
ajlm-1975	46	7	2014	2014	NUM
ajlm-1975	46	8	and	and	CCONJ
ajlm-1975	46	9	december	december	PROPN
ajlm-1975	46	10	2014	2014	NUM
ajlm-1975	46	11	,	,	PUNCT
ajlm-1975	46	12	the	the	DET
ajlm-1975	46	13	automated	automate	VERB
ajlm-1975	46	14	bactec	bactec	ADJ
ajlm-1975	46	15	mycobacteria	mycobacteria	NOUN
ajlm-1975	46	16	growth	growth	NOUN
ajlm-1975	46	17	indicator	indicator	NOUN
ajlm-1975	46	18	tube	tube	NOUN
ajlm-1975	46	19	960	960	NUM
ajlm-1975	46	20	system	system	NOUN
ajlm-1975	46	21	(	(	PUNCT
ajlm-1975	46	22	becton	becton	PROPN
ajlm-1975	46	23	dickinson	dickinson	PROPN
ajlm-1975	46	24	,	,	PUNCT
ajlm-1975	46	25	sparks	spark	VERB
ajlm-1975	46	26	,	,	PUNCT
ajlm-1975	46	27	maryland	maryland	PROPN
ajlm-1975	46	28	,	,	PUNCT
ajlm-1975	46	29	united	united	PROPN
ajlm-1975	46	30	states	states	PROPN
ajlm-1975	46	31	)	)	PUNCT
ajlm-1975	46	32	was	be	AUX
ajlm-1975	46	33	used	use	VERB
ajlm-1975	46	34	for	for	ADP
ajlm-1975	46	35	m.	m.	NOUN
ajlm-1975	46	36	tuberculosis	tuberculosis	NOUN
ajlm-1975	46	37	culture	culture	NOUN
ajlm-1975	46	38	,	,	PUNCT
ajlm-1975	46	39	and	and	CCONJ
ajlm-1975	46	40	initial	initial	ADJ
ajlm-1975	46	41	dst	dst	NOUN
ajlm-1975	46	42	was	be	AUX
ajlm-1975	46	43	done	do	VERB
ajlm-1975	46	44	on	on	ADP
ajlm-1975	46	45	all	all	DET
ajlm-1975	46	46	positive	positive	ADJ
ajlm-1975	46	47	cultures	culture	NOUN
ajlm-1975	46	48	using	use	VERB
ajlm-1975	46	49	the	the	DET
ajlm-1975	46	50	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	46	51	version	version	NOUN
ajlm-1975	46	52	2	2	NUM
ajlm-1975	46	53	assay	assay	NOUN
ajlm-1975	46	54	(	(	PUNCT
ajlm-1975	46	55	hain	hain	NOUN
ajlm-1975	46	56	lifescience	lifescience	NOUN
ajlm-1975	46	57	,	,	PUNCT
ajlm-1975	46	58	nehren	nehren	PROPN
ajlm-1975	46	59	,	,	PUNCT
ajlm-1975	46	60	germany	germany	PROPN
ajlm-1975	46	61	)	)	PUNCT
ajlm-1975	46	62	to	to	PART
ajlm-1975	46	63	confirm	confirm	VERB
ajlm-1975	46	64	rifampicin	rifampicin	VERB
ajlm-1975	46	65	resistance	resistance	NOUN
ajlm-1975	46	66	and	and	CCONJ
ajlm-1975	46	67	test	test	NOUN
ajlm-1975	46	68	for	for	ADP
ajlm-1975	46	69	isoniazid	isoniazid	NOUN
ajlm-1975	46	70	resistance	resistance	NOUN
ajlm-1975	46	71	.	.	PUNCT
ajlm-1975	47	1	the	the	DET
ajlm-1975	47	2	mtbdrplus	mtbdrplus	PROPN
ajlm-1975	47	3	assay	assay	NOUN
ajlm-1975	47	4	uses	use	VERB
ajlm-1975	47	5	dna	dna	PROPN
ajlm-1975	47	6	strip	strip	PROPN
ajlm-1975	47	7	technology	technology	NOUN
ajlm-1975	47	8	where	where	SCONJ
ajlm-1975	47	9	the	the	DET
ajlm-1975	47	10	strip	strip	NOUN
ajlm-1975	47	11	contains	contain	VERB
ajlm-1975	47	12	both	both	PRON
ajlm-1975	47	13	wild	wild	ADJ
ajlm-1975	47	14	-	-	PUNCT
ajlm-1975	47	15	type	type	NOUN
ajlm-1975	47	16	probes	probe	NOUN
ajlm-1975	47	17	and	and	CCONJ
ajlm-1975	47	18	mutation	mutation	NOUN
ajlm-1975	47	19	probes	probe	NOUN
ajlm-1975	47	20	for	for	ADP
ajlm-1975	47	21	the	the	DET
ajlm-1975	47	22	commonly	commonly	ADV
ajlm-1975	47	23	occurring	occur	VERB
ajlm-1975	47	24	mutations	mutation	NOUN
ajlm-1975	47	25	(	(	PUNCT
ajlm-1975	47	26	s450l	s450l	PROPN
ajlm-1975	47	27	,	,	PUNCT
ajlm-1975	47	28	h455y	h455y	PROPN
ajlm-1975	47	29	,	,	PUNCT
ajlm-1975	47	30	h455d	h455d	PROPN
ajlm-1975	47	31	,	,	PUNCT
ajlm-1975	47	32	and	and	CCONJ
ajlm-1975	47	33	d435v	d435v	ADJ
ajlm-1975	47	34	for	for	ADP
ajlm-1975	47	35	rifampicin	rifampicin	NUM
ajlm-1975	47	36	)	)	PUNCT
ajlm-1975	47	37	.	.	PUNCT
ajlm-1975	48	1	the	the	DET
ajlm-1975	48	2	labelled	label	VERB
ajlm-1975	48	3	polymerase	polymerase	NOUN
ajlm-1975	48	4	chain	chain	NOUN
ajlm-1975	48	5	reaction	reaction	NOUN
ajlm-1975	48	6	products	product	NOUN
ajlm-1975	48	7	from	from	ADP
ajlm-1975	48	8	an	an	DET
ajlm-1975	48	9	amplified	amplify	VERB
ajlm-1975	48	10	target	target	NOUN
ajlm-1975	48	11	are	be	AUX
ajlm-1975	48	12	hybridised	hybridise	VERB
ajlm-1975	48	13	with	with	ADP
ajlm-1975	48	14	specific	specific	ADJ
ajlm-1975	48	15	probes	probe	NOUN
ajlm-1975	48	16	immobilised	immobilise	VERB
ajlm-1975	48	17	on	on	ADP
ajlm-1975	48	18	a	a	DET
ajlm-1975	48	19	strip	strip	NOUN
ajlm-1975	48	20	(	(	PUNCT
ajlm-1975	48	21	reverse	reverse	ADJ
ajlm-1975	48	22	hybridisation	hybridisation	NOUN
ajlm-1975	48	23	)	)	PUNCT
ajlm-1975	48	24	.	.	PUNCT
ajlm-1975	49	1	resistance	resistance	NOUN
ajlm-1975	49	2	is	be	AUX
ajlm-1975	49	3	reported	report	VERB
ajlm-1975	49	4	when	when	SCONJ
ajlm-1975	49	5	there	there	PRON
ajlm-1975	49	6	is	be	VERB
ajlm-1975	49	7	a	a	DET
ajlm-1975	49	8	lack	lack	NOUN
ajlm-1975	49	9	of	of	ADP
ajlm-1975	49	10	binding	bind	VERB
ajlm-1975	49	11	to	to	ADP
ajlm-1975	49	12	the	the	DET
ajlm-1975	49	13	wild	wild	ADJ
ajlm-1975	49	14	-	-	PUNCT
ajlm-1975	49	15	type	type	NOUN
ajlm-1975	49	16	probe	probe	NOUN
ajlm-1975	49	17	with	with	ADP
ajlm-1975	49	18	or	or	CCONJ
ajlm-1975	49	19	without	without	ADP
ajlm-1975	49	20	binding	bind	VERB
ajlm-1975	49	21	to	to	ADP
ajlm-1975	49	22	a	a	DET
ajlm-1975	49	23	mutation	mutation	NOUN
ajlm-1975	49	24	probe.14	probe.14	NOUN
ajlm-1975	49	25	isolates	isolate	NOUN
ajlm-1975	49	26	that	that	PRON
ajlm-1975	49	27	were	be	AUX
ajlm-1975	49	28	resistant	resistant	ADJ
ajlm-1975	49	29	to	to	ADP
ajlm-1975	49	30	either	either	CCONJ
ajlm-1975	49	31	rifampicin	rifampicin	VERB
ajlm-1975	49	32	or	or	CCONJ
ajlm-1975	49	33	isoniazid	isoniazid	NOUN
ajlm-1975	49	34	on	on	ADP
ajlm-1975	49	35	the	the	DET
ajlm-1975	49	36	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	49	37	assay	assay	NOUN
ajlm-1975	49	38	were	be	AUX
ajlm-1975	49	39	further	far	ADV
ajlm-1975	49	40	tested	test	VERB
ajlm-1975	49	41	for	for	ADP
ajlm-1975	49	42	resistance	resistance	NOUN
ajlm-1975	49	43	to	to	ADP
ajlm-1975	49	44	critical	critical	ADJ
ajlm-1975	49	45	concentrations	concentration	NOUN
ajlm-1975	49	46	of	of	ADP
ajlm-1975	49	47	isoniazid	isoniazid	NOUN
ajlm-1975	49	48	(	(	PUNCT
ajlm-1975	49	49	0.2	0.2	NUM
ajlm-1975	49	50	µg	µg	ADV
ajlm-1975	49	51	/	/	SYM
ajlm-1975	49	52	ml	ml	NOUN
ajlm-1975	49	53	)	)	PUNCT
ajlm-1975	49	54	,	,	PUNCT
ajlm-1975	49	55	rifampicin	rifampicin	VERB
ajlm-1975	49	56	(	(	PUNCT
ajlm-1975	49	57	1	1	NUM
ajlm-1975	49	58	µg	µg	NOUN
ajlm-1975	49	59	/	/	SYM
ajlm-1975	49	60	ml	ml	NOUN
ajlm-1975	49	61	)	)	PUNCT
ajlm-1975	49	62	,	,	PUNCT
ajlm-1975	49	63	ofloxacin	ofloxacin	NOUN
ajlm-1975	49	64	(	(	PUNCT
ajlm-1975	49	65	2	2	NUM
ajlm-1975	49	66	µg	µg	NOUN
ajlm-1975	49	67	/	/	SYM
ajlm-1975	49	68	ml	ml	NOUN
ajlm-1975	49	69	)	)	PUNCT
ajlm-1975	49	70	,	,	PUNCT
ajlm-1975	49	71	streptomycin	streptomycin	PROPN
ajlm-1975	49	72	(	(	PUNCT
ajlm-1975	49	73	2	2	NUM
ajlm-1975	49	74	µg	µg	NOUN
ajlm-1975	49	75	/	/	SYM
ajlm-1975	49	76	ml	ml	NOUN
ajlm-1975	49	77	)	)	PUNCT
ajlm-1975	49	78	,	,	PUNCT
ajlm-1975	49	79	and	and	CCONJ
ajlm-1975	49	80	kanamycin	kanamycin	PROPN
ajlm-1975	49	81	(	(	PUNCT
ajlm-1975	49	82	5	5	NUM
ajlm-1975	49	83	µg	µg	ADV
ajlm-1975	49	84	/	/	SYM
ajlm-1975	49	85	ml	ml	NOUN
ajlm-1975	49	86	)	)	PUNCT
ajlm-1975	49	87	using	use	VERB
ajlm-1975	49	88	the	the	DET
ajlm-1975	49	89	1	1	NUM
ajlm-1975	49	90	%	%	NOUN
ajlm-1975	49	91	agar	agar	NOUN
ajlm-1975	49	92	proportion	proportion	NOUN
ajlm-1975	49	93	method	method	NOUN
ajlm-1975	49	94	on	on	ADP
ajlm-1975	49	95	middlebrook	middlebrook	PROPN
ajlm-1975	49	96	7h10	7h10	NOUN
ajlm-1975	49	97	agar	agar	NOUN
ajlm-1975	49	98	(	(	PUNCT
ajlm-1975	49	99	becton	becton	PROPN
ajlm-1975	49	100	dickinson	dickinson	PROPN
ajlm-1975	49	101	,	,	PUNCT
ajlm-1975	49	102	sparks	spark	VERB
ajlm-1975	49	103	,	,	PUNCT
ajlm-1975	49	104	maryland	maryland	PROPN
ajlm-1975	49	105	,	,	PUNCT
ajlm-1975	49	106	united	united	PROPN
ajlm-1975	49	107	states).15	states).15	PROPN
ajlm-1975	49	108	the	the	DET
ajlm-1975	49	109	simultaneous	simultaneous	ADJ
ajlm-1975	49	110	performance	performance	NOUN
ajlm-1975	49	111	of	of	ADP
ajlm-1975	49	112	molecular	molecular	ADJ
ajlm-1975	49	113	and	and	CCONJ
ajlm-1975	49	114	phenotypic	phenotypic	ADJ
ajlm-1975	49	115	rifampicin	rifampicin	VERB
ajlm-1975	49	116	dst	dst	PROPN
ajlm-1975	49	117	allowed	allow	VERB
ajlm-1975	49	118	the	the	DET
ajlm-1975	49	119	detection	detection	NOUN
ajlm-1975	49	120	of	of	ADP
ajlm-1975	49	121	discordance	discordance	NOUN
ajlm-1975	49	122	between	between	ADP
ajlm-1975	49	123	these	these	DET
ajlm-1975	49	124	two	two	NUM
ajlm-1975	49	125	tests	test	NOUN
ajlm-1975	49	126	.	.	PUNCT
ajlm-1975	50	1	laboratory	laboratory	NOUN
ajlm-1975	50	2	analysis	analysis	NOUN
ajlm-1975	50	3	routine	routine	ADJ
ajlm-1975	50	4	clinical	clinical	ADJ
ajlm-1975	50	5	isolates	isolate	NOUN
ajlm-1975	50	6	from	from	ADP
ajlm-1975	50	7	specimens	specimen	NOUN
ajlm-1975	50	8	received	receive	VERB
ajlm-1975	50	9	at	at	ADP
ajlm-1975	50	10	the	the	DET
ajlm-1975	50	11	inkosi	inkosi	PROPN
ajlm-1975	50	12	albert	albert	PROPN
ajlm-1975	50	13	luthuli	luthuli	PROPN
ajlm-1975	50	14	central	central	PROPN
ajlm-1975	50	15	hospital	hospital	PROPN
ajlm-1975	50	16	laboratory	laboratory	NOUN
ajlm-1975	50	17	of	of	ADP
ajlm-1975	50	18	the	the	DET
ajlm-1975	50	19	kwazulu	kwazulu	PROPN
ajlm-1975	50	20	-	-	PUNCT
ajlm-1975	50	21	natal	natal	NOUN
ajlm-1975	50	22	province	province	NOUN
ajlm-1975	50	23	between	between	ADP
ajlm-1975	50	24	january	january	PROPN
ajlm-1975	50	25	2014	2014	NUM
ajlm-1975	50	26	and	and	CCONJ
ajlm-1975	50	27	december	december	PROPN
ajlm-1975	50	28	2014	2014	NUM
ajlm-1975	50	29	were	be	AUX
ajlm-1975	50	30	used	use	VERB
ajlm-1975	50	31	for	for	ADP
ajlm-1975	50	32	this	this	DET
ajlm-1975	50	33	study	study	NOUN
ajlm-1975	50	34	.	.	PUNCT
ajlm-1975	51	1	isolates	isolate	NOUN
ajlm-1975	51	2	were	be	AUX
ajlm-1975	51	3	selected	select	VERB
ajlm-1975	51	4	if	if	SCONJ
ajlm-1975	51	5	they	they	PRON
ajlm-1975	51	6	showed	show	VERB
ajlm-1975	51	7	rifampicin	rifampicin	VERB
ajlm-1975	51	8	susceptibility	susceptibility	NOUN
ajlm-1975	51	9	on	on	ADP
ajlm-1975	51	10	the	the	DET
ajlm-1975	51	11	mtbdrplus	mtbdrplus	NOUN
ajlm-1975	51	12	but	but	CCONJ
ajlm-1975	51	13	were	be	AUX
ajlm-1975	51	14	rifampicin	rifampicin	VERB
ajlm-1975	51	15	resistant	resistant	ADJ
ajlm-1975	51	16	on	on	ADP
ajlm-1975	51	17	the	the	DET
ajlm-1975	51	18	1	1	NUM
ajlm-1975	51	19	%	%	NOUN
ajlm-1975	51	20	agar	agar	NOUN
ajlm-1975	51	21	proportion	proportion	NOUN
ajlm-1975	51	22	method	method	NOUN
ajlm-1975	51	23	on	on	ADP
ajlm-1975	51	24	middlebrook	middlebrook	PROPN
ajlm-1975	52	1	7h10	7h10	NUM
ajlm-1975	52	2	agar	agar	NOUN
ajlm-1975	52	3	at	at	ADP
ajlm-1975	52	4	a	a	DET
ajlm-1975	52	5	critical	critical	ADJ
ajlm-1975	52	6	rifampicin	rifampicin	VERB
ajlm-1975	52	7	concentration	concentration	NOUN
ajlm-1975	52	8	of	of	ADP
ajlm-1975	52	9	1	1	NUM
ajlm-1975	52	10	µg	µg	NOUN
ajlm-1975	52	11	/	/	SYM
ajlm-1975	52	12	ml	ml	NOUN
ajlm-1975	52	13	.	.	PUNCT
ajlm-1975	53	1	the	the	DET
ajlm-1975	53	2	isolates	isolate	NOUN
ajlm-1975	53	3	from	from	ADP
ajlm-1975	53	4	2014	2014	NUM
ajlm-1975	53	5	were	be	AUX
ajlm-1975	53	6	chosen	choose	VERB
ajlm-1975	53	7	because	because	SCONJ
ajlm-1975	53	8	simultaneous	simultaneous	ADJ
ajlm-1975	53	9	molecular	molecular	ADJ
ajlm-1975	53	10	and	and	CCONJ
ajlm-1975	53	11	phenotypic	phenotypic	ADJ
ajlm-1975	53	12	rifampicin	rifampicin	VERB
ajlm-1975	53	13	dst	dst	NOUN
ajlm-1975	53	14	was	be	AUX
ajlm-1975	53	15	performed	perform	VERB
ajlm-1975	53	16	during	during	ADP
ajlm-1975	53	17	this	this	DET
ajlm-1975	53	18	time	time	NOUN
ajlm-1975	53	19	but	but	CCONJ
ajlm-1975	53	20	was	be	AUX
ajlm-1975	53	21	subsequently	subsequently	ADV
ajlm-1975	53	22	stopped	stop	VERB
ajlm-1975	53	23	.	.	PUNCT
ajlm-1975	54	1	the	the	DET
ajlm-1975	54	2	selected	select	VERB
ajlm-1975	54	3	isolates	isolate	NOUN
ajlm-1975	54	4	were	be	AUX
ajlm-1975	54	5	then	then	ADV
ajlm-1975	54	6	stored	store	VERB
ajlm-1975	54	7	at	at	ADP
ajlm-1975	54	8	–	–	PUNCT
ajlm-1975	54	9	70	70	NUM
ajlm-1975	54	10	°	°	ADP
ajlm-1975	54	11	c	c	NOUN
ajlm-1975	54	12	and	and	CCONJ
ajlm-1975	54	13	later	later	ADV
ajlm-1975	54	14	used	use	VERB
ajlm-1975	54	15	for	for	ADP
ajlm-1975	54	16	this	this	DET
ajlm-1975	54	17	study	study	NOUN
ajlm-1975	54	18	.	.	PUNCT
ajlm-1975	55	1	of	of	ADP
ajlm-1975	55	2	the	the	DET
ajlm-1975	55	3	isolates	isolate	NOUN
ajlm-1975	55	4	that	that	PRON
ajlm-1975	55	5	had	have	VERB
ajlm-1975	55	6	discordant	discordant	ADJ
ajlm-1975	55	7	rifampicin	rifampicin	VERB
ajlm-1975	55	8	results	result	NOUN
ajlm-1975	55	9	,	,	PUNCT
ajlm-1975	55	10	36	36	NUM
ajlm-1975	55	11	were	be	AUX
ajlm-1975	55	12	randomly	randomly	ADV
ajlm-1975	55	13	selected	select	VERB
ajlm-1975	55	14	for	for	ADP
ajlm-1975	55	15	further	further	ADJ
ajlm-1975	55	16	evaluation	evaluation	NOUN
ajlm-1975	55	17	using	use	VERB
ajlm-1975	55	18	whole	whole	ADJ
ajlm-1975	55	19	-	-	PUNCT
ajlm-1975	55	20	genome	genome	NOUN
ajlm-1975	55	21	sequencing	sequencing	NOUN
ajlm-1975	55	22	.	.	PUNCT
ajlm-1975	56	1	whole	whole	ADJ
ajlm-1975	56	2	-	-	PUNCT
ajlm-1975	56	3	genome	genome	NOUN
ajlm-1975	56	4	sequencing	sequencing	NOUN
ajlm-1975	56	5	stored	store	VERB
ajlm-1975	56	6	isolates	isolate	NOUN
ajlm-1975	56	7	were	be	AUX
ajlm-1975	56	8	grown	grow	VERB
ajlm-1975	56	9	on	on	ADP
ajlm-1975	56	10	7h11	7h11	PROPN
ajlm-1975	56	11	middlebrook	middlebrook	PROPN
ajlm-1975	56	12	agar	agar	VERB
ajlm-1975	56	13	for	for	ADP
ajlm-1975	56	14	over	over	ADP
ajlm-1975	56	15	three	three	NUM
ajlm-1975	56	16	weeks	week	NOUN
ajlm-1975	56	17	.	.	PUNCT
ajlm-1975	57	1	genomic	genomic	PROPN
ajlm-1975	57	2	dna	dna	PROPN
ajlm-1975	57	3	was	be	AUX
ajlm-1975	57	4	extracted	extract	VERB
ajlm-1975	57	5	from	from	ADP
ajlm-1975	57	6	isolates	isolate	NOUN
ajlm-1975	57	7	using	use	VERB
ajlm-1975	57	8	the	the	DET
ajlm-1975	57	9	quick	quick	ADJ
ajlm-1975	57	10	-	-	PUNCT
ajlm-1975	57	11	dna	dna	NOUN
ajlm-1975	57	12	™	™	ADJ
ajlm-1975	57	13	miniprep	miniprep	NOUN
ajlm-1975	57	14	kit	kit	NOUN
ajlm-1975	57	15	(	(	PUNCT
ajlm-1975	57	16	zymo	zymo	NOUN
ajlm-1975	57	17	research	research	NOUN
ajlm-1975	57	18	,	,	PUNCT
ajlm-1975	57	19	irvine	irvine	PROPN
ajlm-1975	57	20	,	,	PUNCT
ajlm-1975	57	21	california	california	PROPN
ajlm-1975	57	22	,	,	PUNCT
ajlm-1975	57	23	united	united	PROPN
ajlm-1975	57	24	states	states	PROPN
ajlm-1975	57	25	)	)	PUNCT
ajlm-1975	57	26	.	.	PUNCT
ajlm-1975	58	1	the	the	DET
ajlm-1975	58	2	concentration	concentration	NOUN
ajlm-1975	58	3	of	of	ADP
ajlm-1975	58	4	dna	dna	PROPN
ajlm-1975	58	5	was	be	AUX
ajlm-1975	58	6	determined	determine	VERB
ajlm-1975	58	7	using	use	VERB
ajlm-1975	58	8	the	the	DET
ajlm-1975	58	9	qubit	qubit	NOUN
ajlm-1975	58	10	dsdna	dsdna	PROPN
ajlm-1975	58	11	hs	hs	PROPN
ajlm-1975	58	12	assay	assay	PROPN
ajlm-1975	58	13	kit	kit	NOUN
ajlm-1975	58	14	(	(	PUNCT
ajlm-1975	58	15	invitrogen	invitrogen	PROPN
ajlm-1975	58	16	,	,	PUNCT
ajlm-1975	58	17	carlsbad	carlsbad	PROPN
ajlm-1975	58	18	,	,	PUNCT
ajlm-1975	58	19	california	california	PROPN
ajlm-1975	58	20	united	united	PROPN
ajlm-1975	58	21	states	states	PROPN
ajlm-1975	58	22	)	)	PUNCT
ajlm-1975	58	23	.	.	PUNCT
ajlm-1975	59	1	a	a	DET
ajlm-1975	59	2	minimum	minimum	NOUN
ajlm-1975	59	3	of	of	ADP
ajlm-1975	59	4	2	2	NUM
ajlm-1975	59	5	ng/µl	ng/µl	NUM
ajlm-1975	59	6	dna	dna	NOUN
ajlm-1975	59	7	was	be	AUX
ajlm-1975	59	8	used	use	VERB
ajlm-1975	59	9	for	for	ADP
ajlm-1975	59	10	library	library	ADJ
ajlm-1975	59	11	preparation	preparation	NOUN
ajlm-1975	59	12	.	.	PUNCT
ajlm-1975	60	1	libraries	library	NOUN
ajlm-1975	60	2	were	be	AUX
ajlm-1975	60	3	prepared	prepare	VERB
ajlm-1975	60	4	using	use	VERB
ajlm-1975	60	5	the	the	DET
ajlm-1975	60	6	nextera	nextera	ADJ
ajlm-1975	60	7	dna	dna	PROPN
ajlm-1975	60	8	library	library	NOUN
ajlm-1975	60	9	preparation	preparation	NOUN
ajlm-1975	60	10	kit	kit	NOUN
ajlm-1975	60	11	and	and	CCONJ
ajlm-1975	60	12	nextera	nextera	PROPN
ajlm-1975	60	13	cd	cd	PROPN
ajlm-1975	60	14	index	index	NOUN
ajlm-1975	60	15	kit	kit	NOUN
ajlm-1975	60	16	(	(	PUNCT
ajlm-1975	60	17	illumina	illumina	PROPN
ajlm-1975	60	18	,	,	PUNCT
ajlm-1975	60	19	san	san	PROPN
ajlm-1975	60	20	diego	diego	PROPN
ajlm-1975	60	21	,	,	PUNCT
ajlm-1975	60	22	california	california	PROPN
ajlm-1975	60	23	united	united	PROPN
ajlm-1975	60	24	states	states	PROPN
ajlm-1975	60	25	)	)	PUNCT
ajlm-1975	60	26	according	accord	VERB
ajlm-1975	60	27	to	to	ADP
ajlm-1975	60	28	the	the	DET
ajlm-1975	60	29	manufacturer	manufacturer	NOUN
ajlm-1975	60	30	’s	’s	PART
ajlm-1975	60	31	protocol	protocol	NOUN
ajlm-1975	60	32	.	.	PUNCT
ajlm-1975	61	1	each	each	DET
ajlm-1975	61	2	library	library	NOUN
ajlm-1975	61	3	was	be	AUX
ajlm-1975	61	4	pooled	pool	VERB
ajlm-1975	61	5	and	and	CCONJ
ajlm-1975	61	6	diluted	dilute	VERB
ajlm-1975	61	7	to	to	ADP
ajlm-1975	61	8	an	an	DET
ajlm-1975	61	9	equimolar	equimolar	ADJ
ajlm-1975	61	10	concentration	concentration	NOUN
ajlm-1975	61	11	of	of	ADP
ajlm-1975	61	12	4	4	NUM
ajlm-1975	61	13	nm	nm	NOUN
ajlm-1975	61	14	followed	follow	VERB
ajlm-1975	61	15	by	by	ADP
ajlm-1975	61	16	denaturation	denaturation	NOUN
ajlm-1975	61	17	and	and	CCONJ
ajlm-1975	61	18	dilution	dilution	NOUN
ajlm-1975	61	19	to	to	ADP
ajlm-1975	61	20	the	the	DET
ajlm-1975	61	21	final	final	ADJ
ajlm-1975	61	22	loading	loading	NOUN
ajlm-1975	61	23	concentration	concentration	NOUN
ajlm-1975	61	24	.	.	PUNCT
ajlm-1975	62	1	the	the	DET
ajlm-1975	62	2	library	library	NOUN
ajlm-1975	62	3	was	be	AUX
ajlm-1975	62	4	spiked	spike	VERB
ajlm-1975	62	5	with	with	ADP
ajlm-1975	62	6	1	1	NUM
ajlm-1975	62	7	%	%	NOUN
ajlm-1975	62	8	phix	phix	NOUN
ajlm-1975	62	9	,	,	PUNCT
ajlm-1975	62	10	which	which	PRON
ajlm-1975	62	11	serves	serve	VERB
ajlm-1975	62	12	as	as	ADP
ajlm-1975	62	13	an	an	DET
ajlm-1975	62	14	internal	internal	ADJ
ajlm-1975	62	15	control	control	NOUN
ajlm-1975	62	16	to	to	PART
ajlm-1975	62	17	account	account	VERB
ajlm-1975	62	18	for	for	ADP
ajlm-1975	62	19	low	low	ADJ
ajlm-1975	62	20	-	-	PUNCT
ajlm-1975	62	21	diversity	diversity	NOUN
ajlm-1975	62	22	libraries	library	NOUN
ajlm-1975	62	23	,	,	PUNCT
ajlm-1975	62	24	and	and	CCONJ
ajlm-1975	62	25	run	run	VERB
ajlm-1975	62	26	on	on	ADP
ajlm-1975	62	27	an	an	DET
ajlm-1975	62	28	illumina	illumina	ADJ
ajlm-1975	62	29	miseq	miseq	PROPN
ajlm-1975	62	30	platform	platform	PROPN
ajlm-1975	62	31	(	(	PUNCT
ajlm-1975	62	32	illumina	illumina	PROPN
ajlm-1975	62	33	,	,	PUNCT
ajlm-1975	62	34	san	san	PROPN
ajlm-1975	62	35	diego	diego	PROPN
ajlm-1975	62	36	,	,	PUNCT
ajlm-1975	62	37	california	california	PROPN
ajlm-1975	62	38	,	,	PUNCT
ajlm-1975	62	39	united	united	PROPN
ajlm-1975	62	40	states	states	PROPN
ajlm-1975	62	41	)	)	PUNCT
ajlm-1975	62	42	using	use	VERB
ajlm-1975	62	43	the	the	DET
ajlm-1975	62	44	miseq	miseq	ADJ
ajlm-1975	62	45	v2	v2	PROPN
ajlm-1975	62	46	500	500	NUM
ajlm-1975	62	47	cycle	cycle	NOUN
ajlm-1975	62	48	reagent	reagent	NOUN
ajlm-1975	62	49	kit	kit	NOUN
ajlm-1975	62	50	(	(	PUNCT
ajlm-1975	62	51	illumina	illumina	PROPN
ajlm-1975	62	52	,	,	PUNCT
ajlm-1975	62	53	san	san	PROPN
ajlm-1975	62	54	diego	diego	PROPN
ajlm-1975	62	55	,	,	PUNCT
ajlm-1975	62	56	california	california	PROPN
ajlm-1975	62	57	,	,	PUNCT
ajlm-1975	62	58	united	united	PROPN
ajlm-1975	62	59	states	states	PROPN
ajlm-1975	62	60	)	)	PUNCT
ajlm-1975	62	61	.	.	PUNCT
ajlm-1975	63	1	drug	drug	NOUN
ajlm-1975	63	2	resistance	resistance	NOUN
ajlm-1975	63	3	and	and	CCONJ
ajlm-1975	63	4	strain	strain	ADJ
ajlm-1975	63	5	-	-	PUNCT
ajlm-1975	63	6	type	type	NOUN
ajlm-1975	63	7	profiles	profile	NOUN
ajlm-1975	63	8	were	be	AUX
ajlm-1975	63	9	determined	determine	VERB
ajlm-1975	63	10	using	use	VERB
ajlm-1975	63	11	the	the	DET
ajlm-1975	63	12	tbprofiler	tbprofiler	ADJ
ajlm-1975	63	13	pipeline	pipeline	NOUN
ajlm-1975	63	14	(	(	PUNCT
ajlm-1975	63	15	http:\\tbdr.lshtm.ac.uk\).16	http:\\tbdr.lshtm.ac.uk\).16	NOUN
ajlm-1975	63	16	mutations	mutation	NOUN
ajlm-1975	63	17	were	be	AUX
ajlm-1975	63	18	called	call	VERB
ajlm-1975	63	19	out	out	ADP
ajlm-1975	63	20	at	at	ADP
ajlm-1975	63	21	100×	100×	ADJ
ajlm-1975	63	22	depth	depth	NOUN
ajlm-1975	63	23	of	of	ADP
ajlm-1975	63	24	coverage	coverage	NOUN
ajlm-1975	63	25	.	.	PUNCT
ajlm-1975	64	1	clinical	clinical	ADJ
ajlm-1975	64	2	data	data	NOUN
ajlm-1975	64	3	patients	patient	NOUN
ajlm-1975	64	4	with	with	ADP
ajlm-1975	64	5	discordant	discordant	ADJ
ajlm-1975	64	6	rifampicin	rifampicin	VERB
ajlm-1975	64	7	susceptibility	susceptibility	NOUN
ajlm-1975	64	8	results	result	NOUN
ajlm-1975	64	9	were	be	AUX
ajlm-1975	64	10	identified	identify	VERB
ajlm-1975	64	11	from	from	ADP
ajlm-1975	64	12	the	the	DET
ajlm-1975	64	13	laboratory	laboratory	NOUN
ajlm-1975	64	14	.	.	PUNCT
ajlm-1975	65	1	further	further	ADJ
ajlm-1975	65	2	laboratory	laboratory	NOUN
ajlm-1975	65	3	results	result	NOUN
ajlm-1975	65	4	(	(	PUNCT
ajlm-1975	65	5	phenotypic	phenotypic	NOUN
ajlm-1975	65	6	dst	dst	PROPN
ajlm-1975	65	7	,	,	PUNCT
ajlm-1975	65	8	hiv	hiv	PROPN
ajlm-1975	65	9	status	status	NOUN
ajlm-1975	65	10	,	,	PUNCT
ajlm-1975	65	11	cd4	cd4	PROPN
ajlm-1975	65	12	count	count	NOUN
ajlm-1975	65	13	,	,	PUNCT
ajlm-1975	65	14	and	and	CCONJ
ajlm-1975	65	15	viral	viral	ADJ
ajlm-1975	65	16	load	load	NOUN
ajlm-1975	65	17	results	result	NOUN
ajlm-1975	65	18	)	)	PUNCT
ajlm-1975	65	19	were	be	AUX
ajlm-1975	65	20	obtained	obtain	VERB
ajlm-1975	65	21	from	from	ADP
ajlm-1975	65	22	the	the	DET
ajlm-1975	65	23	laboratory	laboratory	NOUN
ajlm-1975	65	24	information	information	NOUN
ajlm-1975	65	25	system	system	NOUN
ajlm-1975	65	26	.	.	PUNCT
ajlm-1975	66	1	treatment	treatment	NOUN
ajlm-1975	66	2	data	datum	NOUN
ajlm-1975	66	3	was	be	AUX
ajlm-1975	66	4	obtained	obtain	VERB
ajlm-1975	66	5	from	from	ADP
ajlm-1975	66	6	the	the	DET
ajlm-1975	66	7	electronic	electronic	ADJ
ajlm-1975	66	8	drug	drug	NOUN
ajlm-1975	66	9	-	-	PUNCT
ajlm-1975	66	10	resistant	resistant	ADJ
ajlm-1975	66	11	tuberculosis	tuberculosis	NOUN
ajlm-1975	66	12	treatment	treatment	NOUN
ajlm-1975	66	13	register	register	NOUN
ajlm-1975	66	14	of	of	ADP
ajlm-1975	66	15	the	the	DET
ajlm-1975	66	16	kwazulu	kwazulu	ADJ
ajlm-1975	66	17	-	-	PUNCT
ajlm-1975	66	18	natal	natal	ADJ
ajlm-1975	66	19	provincial	provincial	ADJ
ajlm-1975	66	20	department	department	NOUN
ajlm-1975	66	21	of	of	ADP
ajlm-1975	66	22	health	health	PROPN
ajlm-1975	66	23	.	.	PUNCT
ajlm-1975	67	1	treatment	treatment	NOUN
ajlm-1975	67	2	outcomes	outcome	NOUN
ajlm-1975	67	3	were	be	AUX
ajlm-1975	67	4	defined	define	VERB
ajlm-1975	67	5	according	accord	VERB
ajlm-1975	67	6	to	to	ADP
ajlm-1975	67	7	the	the	DET
ajlm-1975	67	8	who	who	PRON
ajlm-1975	67	9	definitions.17	definitions.17	PROPN
ajlm-1975	67	10	data	datum	NOUN
ajlm-1975	67	11	analysis	analysis	NOUN
ajlm-1975	67	12	the	the	DET
ajlm-1975	67	13	data	datum	NOUN
ajlm-1975	67	14	were	be	AUX
ajlm-1975	67	15	captured	capture	VERB
ajlm-1975	67	16	into	into	ADP
ajlm-1975	67	17	an	an	DET
ajlm-1975	67	18	excel	excel	NOUN
ajlm-1975	67	19	file	file	NOUN
ajlm-1975	67	20	(	(	PUNCT
ajlm-1975	67	21	microsoft	microsoft	PROPN
ajlm-1975	67	22	corp	corp	PROPN
ajlm-1975	67	23	.	.	PROPN
ajlm-1975	67	24	,	,	PUNCT
ajlm-1975	67	25	redmond	redmond	PROPN
ajlm-1975	67	26	,	,	PUNCT
ajlm-1975	67	27	washington	washington	PROPN
ajlm-1975	67	28	,	,	PUNCT
ajlm-1975	67	29	united	united	PROPN
ajlm-1975	67	30	states	states	PROPN
ajlm-1975	67	31	)	)	PUNCT
ajlm-1975	67	32	and	and	CCONJ
ajlm-1975	67	33	cleaned	clean	VERB
ajlm-1975	67	34	and	and	CCONJ
ajlm-1975	67	35	coded	code	VERB
ajlm-1975	67	36	before	before	ADP
ajlm-1975	67	37	being	be	AUX
ajlm-1975	67	38	imported	import	VERB
ajlm-1975	67	39	into	into	ADP
ajlm-1975	67	40	stata	stata	ADJ
ajlm-1975	67	41	version	version	NOUN
ajlm-1975	67	42	13	13	NUM
ajlm-1975	67	43	(	(	PUNCT
ajlm-1975	67	44	statacorp	statacorp	PROPN
ajlm-1975	67	45	,	,	PUNCT
ajlm-1975	67	46	college	college	NOUN
ajlm-1975	67	47	station	station	NOUN
ajlm-1975	67	48	,	,	PUNCT
ajlm-1975	67	49	texas	texas	PROPN
ajlm-1975	67	50	,	,	PUNCT
ajlm-1975	67	51	united	united	PROPN
ajlm-1975	67	52	states	states	PROPN
ajlm-1975	67	53	)	)	PUNCT
ajlm-1975	67	54	for	for	ADP
ajlm-1975	67	55	statistical	statistical	ADJ
ajlm-1975	67	56	analysis	analysis	NOUN
ajlm-1975	67	57	.	.	PUNCT
ajlm-1975	68	1	patient	patient	ADJ
ajlm-1975	68	2	names	name	NOUN
ajlm-1975	68	3	and	and	CCONJ
ajlm-1975	68	4	ages	age	NOUN
ajlm-1975	68	5	were	be	AUX
ajlm-1975	68	6	used	use	VERB
ajlm-1975	68	7	to	to	PART
ajlm-1975	68	8	remove	remove	VERB
ajlm-1975	68	9	duplicate	duplicate	ADJ
ajlm-1975	68	10	entries	entry	NOUN
ajlm-1975	68	11	.	.	PUNCT
ajlm-1975	69	1	descriptive	descriptive	ADJ
ajlm-1975	69	2	analysis	analysis	NOUN
ajlm-1975	69	3	was	be	AUX
ajlm-1975	69	4	conducted	conduct	VERB
ajlm-1975	69	5	on	on	ADP
ajlm-1975	69	6	data	datum	NOUN
ajlm-1975	69	7	for	for	ADP
ajlm-1975	69	8	all	all	DET
ajlm-1975	69	9	patients	patient	NOUN
ajlm-1975	69	10	with	with	ADP
ajlm-1975	69	11	rifampicin	rifampicin	VERB
ajlm-1975	69	12	-	-	PUNCT
ajlm-1975	69	13	discordant	discordant	ADJ
ajlm-1975	69	14	tuberculosis	tuberculosis	NOUN
ajlm-1975	69	15	results	result	NOUN
ajlm-1975	69	16	,	,	PUNCT
ajlm-1975	69	17	as	as	ADV
ajlm-1975	69	18	well	well	ADV
ajlm-1975	69	19	as	as	ADP
ajlm-1975	69	20	those	those	PRON
ajlm-1975	69	21	selected	select	VERB
ajlm-1975	69	22	for	for	ADP
ajlm-1975	69	23	whole	whole	ADJ
ajlm-1975	69	24	-	-	PUNCT
ajlm-1975	69	25	genome	genome	NOUN
ajlm-1975	69	26	sequencing	sequencing	NOUN
ajlm-1975	69	27	.	.	PUNCT
ajlm-1975	70	1	categorical	categorical	ADJ
ajlm-1975	70	2	variables	variable	NOUN
ajlm-1975	70	3	such	such	ADJ
ajlm-1975	70	4	as	as	ADP
ajlm-1975	70	5	sex	sex	NOUN
ajlm-1975	70	6	,	,	PUNCT
ajlm-1975	70	7	hiv	hiv	PROPN
ajlm-1975	70	8	status	status	NOUN
ajlm-1975	70	9	,	,	PUNCT
ajlm-1975	70	10	previous	previous	ADJ
ajlm-1975	70	11	tuberculosis	tuberculosis	NOUN
ajlm-1975	70	12	treatment	treatment	NOUN
ajlm-1975	70	13	,	,	PUNCT
ajlm-1975	70	14	as	as	ADV
ajlm-1975	70	15	well	well	ADV
ajlm-1975	70	16	as	as	ADP
ajlm-1975	70	17	the	the	DET
ajlm-1975	70	18	xpert	xpert	PROPN
ajlm-1975	70	19	,	,	PUNCT
ajlm-1975	70	20	phenotypic	phenotypic	ADJ
ajlm-1975	70	21	dst	dst	NOUN
ajlm-1975	70	22	and	and	CCONJ
ajlm-1975	70	23	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	70	24	results	result	NOUN
ajlm-1975	70	25	,	,	PUNCT
ajlm-1975	70	26	were	be	AUX
ajlm-1975	70	27	presented	present	VERB
ajlm-1975	70	28	as	as	ADP
ajlm-1975	70	29	proportions	proportion	NOUN
ajlm-1975	70	30	and	and	CCONJ
ajlm-1975	70	31	percentages	percentage	NOUN
ajlm-1975	70	32	.	.	PUNCT
ajlm-1975	71	1	continuous	continuous	ADJ
ajlm-1975	71	2	variables	variable	NOUN
ajlm-1975	71	3	such	such	ADJ
ajlm-1975	71	4	as	as	ADP
ajlm-1975	71	5	age	age	NOUN
ajlm-1975	71	6	,	,	PUNCT
ajlm-1975	71	7	cd4	cd4	PROPN
ajlm-1975	71	8	count	count	NOUN
ajlm-1975	71	9	,	,	PUNCT
ajlm-1975	71	10	and	and	CCONJ
ajlm-1975	71	11	the	the	DET
ajlm-1975	71	12	time	time	NOUN
ajlm-1975	71	13	taken	take	VERB
ajlm-1975	71	14	to	to	ADP
ajlm-1975	71	15	treatment	treatment	NOUN
ajlm-1975	71	16	initiation	initiation	NOUN
ajlm-1975	71	17	were	be	AUX
ajlm-1975	71	18	presented	present	VERB
ajlm-1975	71	19	as	as	ADP
ajlm-1975	71	20	means	mean	NOUN
ajlm-1975	71	21	with	with	ADP
ajlm-1975	71	22	standard	standard	ADJ
ajlm-1975	71	23	deviation	deviation	NOUN
ajlm-1975	71	24	.	.	PUNCT
ajlm-1975	72	1	a	a	DET
ajlm-1975	72	2	bivariate	bivariate	ADJ
ajlm-1975	72	3	analysis	analysis	NOUN
ajlm-1975	72	4	was	be	AUX
ajlm-1975	72	5	conducted	conduct	VERB
ajlm-1975	72	6	using	use	VERB
ajlm-1975	72	7	the	the	DET
ajlm-1975	72	8	two	two	NUM
ajlm-1975	72	9	-	-	PUNCT
ajlm-1975	72	10	sample	sample	NOUN
ajlm-1975	72	11	t	t	NOUN
ajlm-1975	72	12	-	-	PUNCT
ajlm-1975	72	13	test	test	NOUN
ajlm-1975	72	14	to	to	PART
ajlm-1975	72	15	compare	compare	VERB
ajlm-1975	72	16	the	the	DET
ajlm-1975	72	17	mean	mean	ADJ
ajlm-1975	72	18	time	time	NOUN
ajlm-1975	72	19	taken	take	VERB
ajlm-1975	72	20	to	to	ADP
ajlm-1975	72	21	treatment	treatment	NOUN
ajlm-1975	72	22	initiation	initiation	NOUN
ajlm-1975	72	23	between	between	ADP
ajlm-1975	72	24	the	the	DET
ajlm-1975	72	25	xpert	xpert	PROPN
ajlm-1975	72	26	-	-	PUNCT
ajlm-1975	72	27	susceptible	susceptible	ADJ
ajlm-1975	72	28	and	and	CCONJ
ajlm-1975	72	29	xpert	xpert	NOUN
ajlm-1975	72	30	-	-	PUNCT
ajlm-1975	72	31	resistant	resistant	ADJ
ajlm-1975	72	32	results	result	NOUN
ajlm-1975	72	33	,	,	PUNCT
ajlm-1975	72	34	and	and	CCONJ
ajlm-1975	72	35	a	a	DET
ajlm-1975	72	36	p	p	NOUN
ajlm-1975	72	37	-	-	PUNCT
ajlm-1975	72	38	value	value	NOUN
ajlm-1975	72	39	of	of	ADP
ajlm-1975	72	40	<	<	X
ajlm-1975	72	41	0.05	0.05	NUM
ajlm-1975	72	42	was	be	AUX
ajlm-1975	72	43	considered	consider	VERB
ajlm-1975	72	44	indicative	indicative	ADJ
ajlm-1975	72	45	of	of	ADP
ajlm-1975	72	46	statistical	statistical	ADJ
ajlm-1975	72	47	significance	significance	NOUN
ajlm-1975	72	48	.	.	PUNCT
ajlm-1975	73	1	results	result	NOUN
ajlm-1975	73	2	in	in	ADP
ajlm-1975	73	3	2014	2014	NUM
ajlm-1975	73	4	,	,	PUNCT
ajlm-1975	73	5	out	out	ADP
ajlm-1975	73	6	of	of	ADP
ajlm-1975	73	7	12	12	NUM
ajlm-1975	73	8	279	279	NUM
ajlm-1975	73	9	m.	m.	NOUN
ajlm-1975	73	10	tuberculosis	tuberculosis	PRON
ajlm-1975	73	11	complex	complex	ADJ
ajlm-1975	73	12	cases	case	NOUN
ajlm-1975	73	13	detected	detect	VERB
ajlm-1975	73	14	using	use	VERB
ajlm-1975	73	15	the	the	DET
ajlm-1975	73	16	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	73	17	assay	assay	NOUN
ajlm-1975	73	18	,	,	PUNCT
ajlm-1975	73	19	505	505	NUM
ajlm-1975	73	20	(	(	PUNCT
ajlm-1975	73	21	4.1	4.1	NUM
ajlm-1975	73	22	%	%	NOUN
ajlm-1975	73	23	)	)	PUNCT
ajlm-1975	73	24	were	be	AUX
ajlm-1975	73	25	isoniazid	isoniazid	NOUN
ajlm-1975	73	26	mono	mono	NOUN
ajlm-1975	73	27	-	-	PUNCT
ajlm-1975	73	28	resistant	resistant	ADJ
ajlm-1975	73	29	.	.	PUNCT
ajlm-1975	74	1	from	from	ADP
ajlm-1975	74	2	the	the	DET
ajlm-1975	74	3	505	505	NUM
ajlm-1975	74	4	isoniazid	isoniazid	NOUN
ajlm-1975	74	5	mono	mono	NOUN
ajlm-1975	74	6	-	-	PUNCT
ajlm-1975	74	7	resistant	resistant	ADJ
ajlm-1975	74	8	cases	case	NOUN
ajlm-1975	74	9	,	,	PUNCT
ajlm-1975	74	10	145	145	NUM
ajlm-1975	74	11	(	(	PUNCT
ajlm-1975	74	12	28.7	28.7	NUM
ajlm-1975	74	13	%	%	NOUN
ajlm-1975	74	14	)	)	PUNCT
ajlm-1975	74	15	were	be	AUX
ajlm-1975	74	16	mdr	mdr	PROPN
ajlm-1975	74	17	-	-	PROPN
ajlm-1975	74	18	tb	tb	NOUN
ajlm-1975	74	19	based	base	VERB
ajlm-1975	74	20	on	on	ADP
ajlm-1975	74	21	the	the	DET
ajlm-1975	74	22	phenotypic	phenotypic	ADJ
ajlm-1975	74	23	1	1	NUM
ajlm-1975	74	24	%	%	NOUN
ajlm-1975	74	25	agar	agar	NOUN
ajlm-1975	74	26	proportion	proportion	NOUN
ajlm-1975	74	27	method	method	NOUN
ajlm-1975	74	28	(	(	PUNCT
ajlm-1975	74	29	i.e.	i.e.	X
ajlm-1975	74	30	,	,	PUNCT
ajlm-1975	74	31	had	have	AUX
ajlm-1975	74	32	discordant	discordant	ADJ
ajlm-1975	74	33	rifampicin	rifampicin	VERB
ajlm-1975	74	34	dst	dst	NOUN
ajlm-1975	74	35	results	result	NOUN
ajlm-1975	74	36	)	)	PUNCT
ajlm-1975	74	37	.	.	PUNCT
ajlm-1975	75	1	the	the	DET
ajlm-1975	75	2	median	median	ADJ
ajlm-1975	75	3	age	age	NOUN
ajlm-1975	75	4	of	of	ADP
ajlm-1975	75	5	the	the	DET
ajlm-1975	75	6	patients	patient	NOUN
ajlm-1975	75	7	with	with	ADP
ajlm-1975	75	8	discordant	discordant	ADJ
ajlm-1975	75	9	rifampicin	rifampicin	VERB
ajlm-1975	75	10	dst	dst	NOUN
ajlm-1975	75	11	results	result	NOUN
ajlm-1975	75	12	was	be	AUX
ajlm-1975	75	13	33.8	33.8	NUM
ajlm-1975	75	14	years	year	NOUN
ajlm-1975	75	15	,	,	PUNCT
ajlm-1975	75	16	and	and	CCONJ
ajlm-1975	75	17	52.4	52.4	NUM
ajlm-1975	75	18	%	%	NOUN
ajlm-1975	75	19	were	be	AUX
ajlm-1975	75	20	male	male	ADJ
ajlm-1975	75	21	(	(	PUNCT
ajlm-1975	75	22	table	table	NOUN
ajlm-1975	75	23	1	1	NUM
ajlm-1975	75	24	)	)	PUNCT
ajlm-1975	75	25	.	.	PUNCT
ajlm-1975	76	1	table	table	NOUN
ajlm-1975	76	2	1	1	NUM
ajlm-1975	76	3	:	:	PUNCT
ajlm-1975	76	4	 	 	SPACE
ajlm-1975	76	5	patient	patient	ADJ
ajlm-1975	76	6	characteristics	characteristic	NOUN
ajlm-1975	76	7	of	of	ADP
ajlm-1975	76	8	isolates	isolate	NOUN
ajlm-1975	76	9	with	with	ADP
ajlm-1975	76	10	rpob	rpob	ADJ
ajlm-1975	76	11	gene	gene	NOUN
ajlm-1975	76	12	mutations	mutation	NOUN
ajlm-1975	76	13	missed	miss	VERB
ajlm-1975	76	14	by	by	ADP
ajlm-1975	76	15	the	the	DET
ajlm-1975	76	16	genotype	genotype	NOUN
ajlm-1975	76	17	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	76	18	assay	assay	NOUN
ajlm-1975	76	19	at	at	ADP
ajlm-1975	76	20	inkosi	inkosi	PROPN
ajlm-1975	76	21	albert	albert	PROPN
ajlm-1975	76	22	luthuli	luthuli	PROPN
ajlm-1975	76	23	central	central	PROPN
ajlm-1975	76	24	hospital	hospital	PROPN
ajlm-1975	76	25	laboratory	laboratory	NOUN
ajlm-1975	76	26	in	in	ADP
ajlm-1975	76	27	kwazulu	kwazulu	PROPN
ajlm-1975	76	28	-	-	PUNCT
ajlm-1975	76	29	natal	natal	ADJ
ajlm-1975	76	30	,	,	PUNCT
ajlm-1975	76	31	south	south	PROPN
ajlm-1975	76	32	africa	africa	PROPN
ajlm-1975	76	33	between	between	ADP
ajlm-1975	76	34	january	january	PROPN
ajlm-1975	76	35	2014	2014	NUM
ajlm-1975	76	36	and	and	CCONJ
ajlm-1975	76	37	december	december	PROPN
ajlm-1975	76	38	2014	2014	NUM
ajlm-1975	76	39	.	.	PUNCT
ajlm-1975	77	1	microbiology	microbiology	NOUN
ajlm-1975	77	2	results	result	VERB
ajlm-1975	77	3	out	out	ADP
ajlm-1975	77	4	of	of	ADP
ajlm-1975	77	5	the	the	DET
ajlm-1975	77	6	145	145	NUM
ajlm-1975	77	7	isolates	isolate	NOUN
ajlm-1975	77	8	with	with	ADP
ajlm-1975	77	9	discordant	discordant	ADJ
ajlm-1975	77	10	rifampicin	rifampicin	VERB
ajlm-1975	77	11	dst	dst	NOUN
ajlm-1975	77	12	results	result	NOUN
ajlm-1975	77	13	,	,	PUNCT
ajlm-1975	77	14	phenotypic	phenotypic	NOUN
ajlm-1975	77	15	dst	dst	NOUN
ajlm-1975	77	16	showed	show	VERB
ajlm-1975	77	17	that	that	SCONJ
ajlm-1975	77	18	79	79	NUM
ajlm-1975	77	19	(	(	PUNCT
ajlm-1975	77	20	54.5	54.5	NUM
ajlm-1975	77	21	%	%	NOUN
ajlm-1975	77	22	)	)	PUNCT
ajlm-1975	77	23	were	be	AUX
ajlm-1975	77	24	mdr	mdr	PROPN
ajlm-1975	77	25	-	-	PROPN
ajlm-1975	77	26	tb	tb	PROPN
ajlm-1975	77	27	plus	plus	CCONJ
ajlm-1975	77	28	streptomycin	streptomycin	PROPN
ajlm-1975	77	29	resistant	resistant	ADJ
ajlm-1975	77	30	,	,	PUNCT
ajlm-1975	77	31	43	43	NUM
ajlm-1975	77	32	(	(	PUNCT
ajlm-1975	77	33	29.7	29.7	NUM
ajlm-1975	77	34	%	%	NOUN
ajlm-1975	77	35	)	)	PUNCT
ajlm-1975	77	36	were	be	AUX
ajlm-1975	77	37	mdr	mdr	PROPN
ajlm-1975	77	38	-	-	PROPN
ajlm-1975	77	39	tb	tb	NOUN
ajlm-1975	77	40	,	,	PUNCT
ajlm-1975	77	41	10	10	NUM
ajlm-1975	77	42	(	(	PUNCT
ajlm-1975	77	43	6.9	6.9	NUM
ajlm-1975	77	44	%	%	NOUN
ajlm-1975	77	45	)	)	PUNCT
ajlm-1975	77	46	were	be	AUX
ajlm-1975	77	47	mdr	mdr	PROPN
ajlm-1975	77	48	-	-	PROPN
ajlm-1975	77	49	tb	tb	ADP
ajlm-1975	77	50	plus	plus	CCONJ
ajlm-1975	77	51	resistance	resistance	NOUN
ajlm-1975	77	52	to	to	ADP
ajlm-1975	77	53	a	a	DET
ajlm-1975	77	54	fluoroquinolone	fluoroquinolone	NOUN
ajlm-1975	77	55	,	,	PUNCT
ajlm-1975	77	56	seven	seven	NUM
ajlm-1975	77	57	(	(	PUNCT
ajlm-1975	77	58	4.8	4.8	NUM
ajlm-1975	77	59	%	%	NOUN
ajlm-1975	77	60	)	)	PUNCT
ajlm-1975	77	61	were	be	AUX
ajlm-1975	77	62	mdr	mdr	PROPN
ajlm-1975	77	63	-	-	PROPN
ajlm-1975	77	64	tb	tb	ADP
ajlm-1975	77	65	plus	plus	CCONJ
ajlm-1975	77	66	resistance	resistance	NOUN
ajlm-1975	77	67	to	to	ADP
ajlm-1975	77	68	a	a	DET
ajlm-1975	77	69	fluoroquinolone	fluoroquinolone	NOUN
ajlm-1975	77	70	and	and	CCONJ
ajlm-1975	77	71	any	any	DET
ajlm-1975	77	72	second	second	ADJ
ajlm-1975	77	73	-	-	PUNCT
ajlm-1975	77	74	line	line	NOUN
ajlm-1975	77	75	injectable	injectable	ADJ
ajlm-1975	77	76	agent	agent	NOUN
ajlm-1975	77	77	,	,	PUNCT
ajlm-1975	77	78	five	five	NUM
ajlm-1975	77	79	(	(	PUNCT
ajlm-1975	77	80	3.5	3.5	NUM
ajlm-1975	77	81	%	%	NOUN
ajlm-1975	77	82	)	)	PUNCT
ajlm-1975	77	83	were	be	AUX
ajlm-1975	77	84	mdr	mdr	PROPN
ajlm-1975	77	85	-	-	PROPN
ajlm-1975	77	86	tb	tb	ADP
ajlm-1975	77	87	plus	plus	CCONJ
ajlm-1975	77	88	resistance	resistance	NOUN
ajlm-1975	77	89	to	to	ADP
ajlm-1975	77	90	a	a	DET
ajlm-1975	77	91	second	second	ADJ
ajlm-1975	77	92	-	-	PUNCT
ajlm-1975	77	93	line	line	NOUN
ajlm-1975	77	94	injectable	injectable	ADJ
ajlm-1975	77	95	agent	agent	NOUN
ajlm-1975	77	96	,	,	PUNCT
ajlm-1975	77	97	and	and	CCONJ
ajlm-1975	77	98	one	one	NUM
ajlm-1975	77	99	(	(	PUNCT
ajlm-1975	77	100	0.7	0.7	NUM
ajlm-1975	77	101	%	%	NOUN
ajlm-1975	77	102	)	)	PUNCT
ajlm-1975	77	103	was	be	AUX
ajlm-1975	77	104	rifampicin	rifampicin	VERB
ajlm-1975	77	105	mono	mono	NOUN
ajlm-1975	77	106	-	-	PUNCT
ajlm-1975	77	107	resistant	resistant	ADJ
ajlm-1975	77	108	.	.	PUNCT
ajlm-1975	78	1	xpert	xpert	PROPN
ajlm-1975	78	2	results	result	NOUN
ajlm-1975	78	3	were	be	AUX
ajlm-1975	78	4	available	available	ADJ
ajlm-1975	78	5	for	for	ADP
ajlm-1975	78	6	97	97	NUM
ajlm-1975	78	7	(	(	PUNCT
ajlm-1975	78	8	66.9	66.9	NUM
ajlm-1975	78	9	%	%	NOUN
ajlm-1975	78	10	)	)	PUNCT
ajlm-1975	78	11	of	of	ADP
ajlm-1975	78	12	the	the	DET
ajlm-1975	78	13	145	145	NUM
ajlm-1975	78	14	patients	patient	NOUN
ajlm-1975	78	15	.	.	PUNCT
ajlm-1975	79	1	of	of	ADP
ajlm-1975	79	2	these	these	PRON
ajlm-1975	79	3	,	,	PUNCT
ajlm-1975	79	4	37	37	NUM
ajlm-1975	79	5	(	(	PUNCT
ajlm-1975	79	6	38.1	38.1	NUM
ajlm-1975	79	7	%	%	NOUN
ajlm-1975	79	8	)	)	PUNCT
ajlm-1975	79	9	were	be	AUX
ajlm-1975	79	10	rifampicin	rifampicin	VERB
ajlm-1975	79	11	resistant	resistant	ADJ
ajlm-1975	79	12	,	,	PUNCT
ajlm-1975	79	13	and	and	CCONJ
ajlm-1975	79	14	60	60	NUM
ajlm-1975	79	15	(	(	PUNCT
ajlm-1975	79	16	61.9	61.9	NUM
ajlm-1975	79	17	%	%	NOUN
ajlm-1975	79	18	)	)	PUNCT
ajlm-1975	79	19	were	be	AUX
ajlm-1975	79	20	susceptible	susceptible	ADJ
ajlm-1975	79	21	.	.	PUNCT
ajlm-1975	80	1	treatment	treatment	NOUN
ajlm-1975	80	2	details	detail	NOUN
ajlm-1975	80	3	patient	patient	NOUN
ajlm-1975	80	4	records	record	NOUN
ajlm-1975	80	5	were	be	AUX
ajlm-1975	80	6	found	find	VERB
ajlm-1975	80	7	for	for	ADP
ajlm-1975	80	8	108	108	NUM
ajlm-1975	80	9	(	(	PUNCT
ajlm-1975	80	10	74.5	74.5	NUM
ajlm-1975	80	11	%	%	NOUN
ajlm-1975	80	12	)	)	PUNCT
ajlm-1975	80	13	of	of	ADP
ajlm-1975	80	14	the	the	DET
ajlm-1975	80	15	145	145	NUM
ajlm-1975	80	16	isolates	isolate	NOUN
ajlm-1975	80	17	on	on	ADP
ajlm-1975	80	18	the	the	DET
ajlm-1975	80	19	dr	dr	PROPN
ajlm-1975	80	20	-	-	PUNCT
ajlm-1975	80	21	tb	tb	NOUN
ajlm-1975	80	22	treatment	treatment	NOUN
ajlm-1975	80	23	register	register	NOUN
ajlm-1975	80	24	.	.	PUNCT
ajlm-1975	81	1	of	of	ADP
ajlm-1975	81	2	these	these	PRON
ajlm-1975	81	3	,	,	PUNCT
ajlm-1975	81	4	71	71	NUM
ajlm-1975	81	5	(	(	PUNCT
ajlm-1975	81	6	65.7	65.7	NUM
ajlm-1975	81	7	%	%	NOUN
ajlm-1975	81	8	)	)	PUNCT
ajlm-1975	82	1	patients	patient	NOUN
ajlm-1975	82	2	had	have	VERB
ajlm-1975	82	3	a	a	DET
ajlm-1975	82	4	previous	previous	ADJ
ajlm-1975	82	5	tuberculosis	tuberculosis	NOUN
ajlm-1975	82	6	treatment	treatment	NOUN
ajlm-1975	82	7	history	history	NOUN
ajlm-1975	82	8	.	.	PUNCT
ajlm-1975	83	1	sixty	sixty	NUM
ajlm-1975	83	2	-	-	PUNCT
ajlm-1975	83	3	seven	seven	NUM
ajlm-1975	83	4	(	(	PUNCT
ajlm-1975	83	5	62.0	62.0	NUM
ajlm-1975	83	6	%	%	NOUN
ajlm-1975	83	7	)	)	PUNCT
ajlm-1975	83	8	patients	patient	NOUN
ajlm-1975	83	9	had	have	VERB
ajlm-1975	83	10	favourable	favourable	ADJ
ajlm-1975	83	11	treatment	treatment	NOUN
ajlm-1975	83	12	outcomes	outcome	NOUN
ajlm-1975	83	13	(	(	PUNCT
ajlm-1975	83	14	cured	cure	VERB
ajlm-1975	83	15	and	and	CCONJ
ajlm-1975	83	16	treatment	treatment	NOUN
ajlm-1975	83	17	completed	complete	VERB
ajlm-1975	83	18	)	)	PUNCT
ajlm-1975	83	19	and	and	CCONJ
ajlm-1975	83	20	the	the	DET
ajlm-1975	83	21	average	average	ADJ
ajlm-1975	83	22	treatment	treatment	NOUN
ajlm-1975	83	23	duration	duration	NOUN
ajlm-1975	83	24	was	be	AUX
ajlm-1975	83	25	18.4	18.4	NUM
ajlm-1975	83	26	months	month	NOUN
ajlm-1975	83	27	.	.	PUNCT
ajlm-1975	84	1	seventy	seventy	NUM
ajlm-1975	84	2	-	-	PUNCT
ajlm-1975	84	3	six	six	NUM
ajlm-1975	84	4	(	(	PUNCT
ajlm-1975	84	5	70.4	70.4	NUM
ajlm-1975	84	6	%	%	NOUN
ajlm-1975	84	7	)	)	PUNCT
ajlm-1975	84	8	patients	patient	NOUN
ajlm-1975	84	9	on	on	ADP
ajlm-1975	84	10	the	the	DET
ajlm-1975	84	11	dr	dr	PROPN
ajlm-1975	84	12	-	-	PUNCT
ajlm-1975	84	13	tb	tb	NOUN
ajlm-1975	84	14	treatment	treatment	NOUN
ajlm-1975	84	15	register	register	NOUN
ajlm-1975	84	16	had	have	VERB
ajlm-1975	84	17	an	an	DET
ajlm-1975	84	18	xpert	xpert	PROPN
ajlm-1975	84	19	result	result	NOUN
ajlm-1975	84	20	;	;	PUNCT
ajlm-1975	84	21	34	34	NUM
ajlm-1975	84	22	of	of	ADP
ajlm-1975	84	23	these	these	PRON
ajlm-1975	84	24	were	be	AUX
ajlm-1975	84	25	rifampicin	rifampicin	VERB
ajlm-1975	84	26	resistant	resistant	ADJ
ajlm-1975	84	27	and	and	CCONJ
ajlm-1975	84	28	42	42	NUM
ajlm-1975	84	29	were	be	AUX
ajlm-1975	84	30	rifampicin	rifampicin	VERB
ajlm-1975	84	31	susceptible	susceptible	ADJ
ajlm-1975	84	32	(	(	PUNCT
ajlm-1975	84	33	table	table	NOUN
ajlm-1975	84	34	2	2	NUM
ajlm-1975	84	35	)	)	PUNCT
ajlm-1975	84	36	.	.	PUNCT
ajlm-1975	85	1	the	the	DET
ajlm-1975	85	2	mean	mean	ADJ
ajlm-1975	85	3	time	time	NOUN
ajlm-1975	85	4	to	to	ADP
ajlm-1975	85	5	dr	dr	PROPN
ajlm-1975	85	6	-	-	PUNCT
ajlm-1975	85	7	tb	tb	NOUN
ajlm-1975	85	8	treatment	treatment	NOUN
ajlm-1975	85	9	initiation	initiation	NOUN
ajlm-1975	85	10	was	be	AUX
ajlm-1975	85	11	32.7	32.7	NUM
ajlm-1975	85	12	days	day	NOUN
ajlm-1975	85	13	for	for	ADP
ajlm-1975	85	14	patients	patient	NOUN
ajlm-1975	85	15	with	with	ADP
ajlm-1975	85	16	rifampicin	rifampicin	NOUN
ajlm-1975	85	17	-	-	PUNCT
ajlm-1975	85	18	resistant	resistant	ADJ
ajlm-1975	85	19	xpert	xpert	NOUN
ajlm-1975	85	20	results	result	NOUN
ajlm-1975	85	21	,	,	PUNCT
ajlm-1975	85	22	and	and	CCONJ
ajlm-1975	85	23	186.6	186.6	NUM
ajlm-1975	85	24	days	day	NOUN
ajlm-1975	85	25	for	for	ADP
ajlm-1975	85	26	patients	patient	NOUN
ajlm-1975	85	27	with	with	ADP
ajlm-1975	85	28	rifampicin	rifampicin	VERB
ajlm-1975	85	29	-	-	PUNCT
ajlm-1975	85	30	susceptible	susceptible	ADJ
ajlm-1975	85	31	xpert	xpert	PROPN
ajlm-1975	85	32	results	result	NOUN
ajlm-1975	85	33	.	.	PUNCT
ajlm-1975	86	1	the	the	DET
ajlm-1975	86	2	difference	difference	NOUN
ajlm-1975	86	3	in	in	ADP
ajlm-1975	86	4	the	the	DET
ajlm-1975	86	5	time	time	NOUN
ajlm-1975	86	6	to	to	ADP
ajlm-1975	86	7	treatment	treatment	NOUN
ajlm-1975	86	8	between	between	ADP
ajlm-1975	86	9	the	the	DET
ajlm-1975	86	10	two	two	NUM
ajlm-1975	86	11	groups	group	NOUN
ajlm-1975	86	12	was	be	AUX
ajlm-1975	86	13	statistically	statistically	ADV
ajlm-1975	86	14	significant	significant	ADJ
ajlm-1975	86	15	(	(	PUNCT
ajlm-1975	86	16	p	p	X
ajlm-1975	86	17	<	<	X
ajlm-1975	86	18	0.001	0.001	NUM
ajlm-1975	86	19	)	)	PUNCT
ajlm-1975	86	20	.	.	PUNCT
ajlm-1975	87	1	table	table	NOUN
ajlm-1975	87	2	2	2	NUM
ajlm-1975	87	3	:	:	PUNCT
ajlm-1975	87	4	 	 	SPACE
ajlm-1975	87	5	time	time	NOUN
ajlm-1975	87	6	from	from	ADP
ajlm-1975	87	7	availability	availability	NOUN
ajlm-1975	87	8	of	of	ADP
ajlm-1975	87	9	results	result	NOUN
ajlm-1975	87	10	to	to	ADP
ajlm-1975	87	11	initiation	initiation	NOUN
ajlm-1975	87	12	of	of	ADP
ajlm-1975	87	13	drug	drug	NOUN
ajlm-1975	87	14	-	-	PUNCT
ajlm-1975	87	15	resistant	resistant	ADJ
ajlm-1975	87	16	tuberculosis	tuberculosis	NOUN
ajlm-1975	87	17	treatment	treatment	NOUN
ajlm-1975	87	18	in	in	ADP
ajlm-1975	87	19	patients	patient	NOUN
ajlm-1975	87	20	with	with	ADP
ajlm-1975	87	21	m.	m.	NOUN
ajlm-1975	87	22	tuberculosis	tuberculosis	NOUN
ajlm-1975	87	23	isolates	isolate	NOUN
ajlm-1975	87	24	with	with	ADP
ajlm-1975	87	25	discordant	discordant	ADJ
ajlm-1975	87	26	rifampicin	rifampicin	VERB
ajlm-1975	87	27	susceptibility	susceptibility	NOUN
ajlm-1975	87	28	results	result	NOUN
ajlm-1975	87	29	in	in	ADP
ajlm-1975	87	30	kwazulu	kwazulu	NOUN
ajlm-1975	87	31	-	-	PUNCT
ajlm-1975	87	32	natal	natal	ADJ
ajlm-1975	87	33	,	,	PUNCT
ajlm-1975	87	34	south	south	PROPN
ajlm-1975	87	35	africa	africa	PROPN
ajlm-1975	87	36	between	between	ADP
ajlm-1975	87	37	january	january	PROPN
ajlm-1975	87	38	2014	2014	NUM
ajlm-1975	87	39	and	and	CCONJ
ajlm-1975	87	40	december	december	PROPN
ajlm-1975	87	41	2014	2014	NUM
ajlm-1975	87	42	.	.	PUNCT
ajlm-1975	88	1	when	when	SCONJ
ajlm-1975	88	2	calculating	calculate	VERB
ajlm-1975	88	3	the	the	DET
ajlm-1975	88	4	mean	mean	ADJ
ajlm-1975	88	5	time	time	NOUN
ajlm-1975	88	6	to	to	PART
ajlm-1975	88	7	results	result	NOUN
ajlm-1975	88	8	in	in	ADP
ajlm-1975	88	9	reference	reference	NOUN
ajlm-1975	88	10	to	to	ADP
ajlm-1975	88	11	the	the	DET
ajlm-1975	88	12	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	88	13	assay	assay	NOUN
ajlm-1975	88	14	and	and	CCONJ
ajlm-1975	88	15	phenotypic	phenotypic	ADJ
ajlm-1975	88	16	dst	dst	NOUN
ajlm-1975	88	17	results	result	NOUN
ajlm-1975	88	18	,	,	PUNCT
ajlm-1975	88	19	the	the	DET
ajlm-1975	88	20	34	34	NUM
ajlm-1975	88	21	xpert	xpert	PROPN
ajlm-1975	88	22	rifampicin	rifampicin	VERB
ajlm-1975	88	23	resistant	resistant	ADJ
ajlm-1975	88	24	cases	case	NOUN
ajlm-1975	88	25	were	be	AUX
ajlm-1975	88	26	removed	remove	VERB
ajlm-1975	88	27	.	.	PUNCT
ajlm-1975	89	1	additionally	additionally	ADV
ajlm-1975	89	2	,	,	PUNCT
ajlm-1975	89	3	in	in	ADP
ajlm-1975	89	4	two	two	NUM
ajlm-1975	89	5	other	other	ADJ
ajlm-1975	89	6	patients	patient	NOUN
ajlm-1975	89	7	initiated	initiate	VERB
ajlm-1975	89	8	on	on	ADP
ajlm-1975	89	9	treatment	treatment	NOUN
ajlm-1975	89	10	,	,	PUNCT
ajlm-1975	89	11	the	the	DET
ajlm-1975	89	12	date	date	NOUN
ajlm-1975	89	13	of	of	ADP
ajlm-1975	89	14	initiation	initiation	NOUN
ajlm-1975	89	15	was	be	AUX
ajlm-1975	89	16	not	not	PART
ajlm-1975	89	17	recorded	record	VERB
ajlm-1975	89	18	.	.	PUNCT
ajlm-1975	90	1	of	of	ADP
ajlm-1975	90	2	the	the	DET
ajlm-1975	90	3	remaining	remain	VERB
ajlm-1975	90	4	72	72	NUM
ajlm-1975	90	5	patients	patient	NOUN
ajlm-1975	90	6	,	,	PUNCT
ajlm-1975	90	7	11	11	NUM
ajlm-1975	90	8	patients	patient	NOUN
ajlm-1975	90	9	started	start	VERB
ajlm-1975	90	10	treatment	treatment	NOUN
ajlm-1975	90	11	before	before	SCONJ
ajlm-1975	90	12	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	90	13	results	result	NOUN
ajlm-1975	90	14	became	become	VERB
ajlm-1975	90	15	available	available	ADJ
ajlm-1975	90	16	,	,	PUNCT
ajlm-1975	90	17	while	while	SCONJ
ajlm-1975	90	18	61	61	NUM
ajlm-1975	90	19	started	start	VERB
ajlm-1975	90	20	treatment	treatment	NOUN
ajlm-1975	90	21	after	after	ADP
ajlm-1975	90	22	a	a	DET
ajlm-1975	90	23	mean	mean	NOUN
ajlm-1975	90	24	of	of	ADP
ajlm-1975	90	25	93.7	93.7	NUM
ajlm-1975	90	26	days	day	NOUN
ajlm-1975	90	27	from	from	ADP
ajlm-1975	90	28	the	the	DET
ajlm-1975	90	29	availability	availability	NOUN
ajlm-1975	90	30	of	of	ADP
ajlm-1975	90	31	results	result	NOUN
ajlm-1975	90	32	.	.	PUNCT
ajlm-1975	91	1	similarly	similarly	ADV
ajlm-1975	91	2	,	,	PUNCT
ajlm-1975	91	3	for	for	ADP
ajlm-1975	91	4	phenotypic	phenotypic	ADJ
ajlm-1975	91	5	dst	dst	NOUN
ajlm-1975	91	6	,	,	PUNCT
ajlm-1975	91	7	49	49	NUM
ajlm-1975	91	8	of	of	ADP
ajlm-1975	91	9	the	the	DET
ajlm-1975	91	10	72	72	NUM
ajlm-1975	91	11	patients	patient	NOUN
ajlm-1975	91	12	started	start	VERB
ajlm-1975	91	13	treatment	treatment	NOUN
ajlm-1975	91	14	prior	prior	ADV
ajlm-1975	91	15	to	to	ADP
ajlm-1975	91	16	the	the	DET
ajlm-1975	91	17	availability	availability	NOUN
ajlm-1975	91	18	of	of	ADP
ajlm-1975	91	19	results	result	NOUN
ajlm-1975	91	20	while	while	SCONJ
ajlm-1975	91	21	23	23	NUM
ajlm-1975	91	22	started	start	VERB
ajlm-1975	91	23	treatment	treatment	NOUN
ajlm-1975	91	24	after	after	ADP
ajlm-1975	91	25	(	(	PUNCT
ajlm-1975	91	26	mean	mean	NOUN
ajlm-1975	91	27	19.8	19.8	NUM
ajlm-1975	91	28	days	day	NOUN
ajlm-1975	91	29	)	)	PUNCT
ajlm-1975	91	30	results	result	NOUN
ajlm-1975	91	31	were	be	AUX
ajlm-1975	91	32	available	available	ADJ
ajlm-1975	91	33	.	.	PUNCT
ajlm-1975	92	1	whole	whole	ADJ
ajlm-1975	92	2	-	-	PUNCT
ajlm-1975	92	3	genome	genome	NOUN
ajlm-1975	92	4	sequencing	sequencing	NOUN
ajlm-1975	92	5	results	result	NOUN
ajlm-1975	92	6	out	out	ADP
ajlm-1975	92	7	of	of	ADP
ajlm-1975	92	8	the	the	DET
ajlm-1975	92	9	36	36	NUM
ajlm-1975	92	10	isolates	isolate	NOUN
ajlm-1975	92	11	whose	whose	DET
ajlm-1975	92	12	whole	whole	ADJ
ajlm-1975	92	13	genomes	genome	NOUN
ajlm-1975	92	14	were	be	AUX
ajlm-1975	92	15	sequenced	sequence	VERB
ajlm-1975	92	16	,	,	PUNCT
ajlm-1975	92	17	19	19	NUM
ajlm-1975	92	18	(	(	PUNCT
ajlm-1975	92	19	52.8	52.8	NUM
ajlm-1975	92	20	%	%	NOUN
ajlm-1975	92	21	)	)	PUNCT
ajlm-1975	92	22	had	have	VERB
ajlm-1975	92	23	single	single	ADJ
ajlm-1975	92	24	rpob	rpob	ADJ
ajlm-1975	92	25	mutations	mutation	NOUN
ajlm-1975	92	26	outside	outside	ADP
ajlm-1975	92	27	the	the	DET
ajlm-1975	92	28	rrdr	rrdr	NOUN
ajlm-1975	92	29	,	,	PUNCT
ajlm-1975	92	30	namely	namely	ADV
ajlm-1975	92	31	i491f	i491f	PROPN
ajlm-1975	92	32	(	(	PUNCT
ajlm-1975	92	33	16	16	NUM
ajlm-1975	92	34	isolates	isolate	NOUN
ajlm-1975	92	35	;	;	PUNCT
ajlm-1975	92	36	44.4	44.4	NUM
ajlm-1975	92	37	%	%	NOUN
ajlm-1975	92	38	)	)	PUNCT
ajlm-1975	92	39	,	,	PUNCT
ajlm-1975	92	40	v170f	v170f	PROPN
ajlm-1975	92	41	(	(	PUNCT
ajlm-1975	92	42	2	2	NUM
ajlm-1975	92	43	;	;	PUNCT
ajlm-1975	92	44	5.6	5.6	NUM
ajlm-1975	92	45	%	%	NOUN
ajlm-1975	92	46	)	)	PUNCT
ajlm-1975	92	47	and	and	CCONJ
ajlm-1975	92	48	p483l	p483l	NOUN
ajlm-1975	92	49	(	(	PUNCT
ajlm-1975	92	50	1	1	NUM
ajlm-1975	92	51	;	;	PUNCT
ajlm-1975	92	52	2.8	2.8	NUM
ajlm-1975	92	53	%	%	NOUN
ajlm-1975	92	54	)	)	PUNCT
ajlm-1975	92	55	(	(	PUNCT
ajlm-1975	92	56	figure	figure	NOUN
ajlm-1975	92	57	1	1	NUM
ajlm-1975	92	58	)	)	PUNCT
ajlm-1975	92	59	.	.	PUNCT
ajlm-1975	93	1	there	there	PRON
ajlm-1975	93	2	were	be	VERB
ajlm-1975	93	3	14	14	NUM
ajlm-1975	93	4	(	(	PUNCT
ajlm-1975	93	5	38.9	38.9	NUM
ajlm-1975	93	6	%	%	NOUN
ajlm-1975	93	7	)	)	PUNCT
ajlm-1975	93	8	isolates	isolate	NOUN
ajlm-1975	93	9	with	with	ADP
ajlm-1975	93	10	single	single	ADJ
ajlm-1975	93	11	rpob	rpob	ADJ
ajlm-1975	93	12	mutations	mutation	NOUN
ajlm-1975	93	13	located	locate	VERB
ajlm-1975	93	14	within	within	ADP
ajlm-1975	93	15	the	the	DET
ajlm-1975	93	16	rrdr	rrdr	NOUN
ajlm-1975	93	17	,	,	PUNCT
ajlm-1975	93	18	namely	namely	ADV
ajlm-1975	93	19	12	12	NUM
ajlm-1975	93	20	isolates	isolate	NOUN
ajlm-1975	93	21	(	(	PUNCT
ajlm-1975	93	22	33.3	33.3	NUM
ajlm-1975	93	23	%	%	NOUN
ajlm-1975	93	24	)	)	PUNCT
ajlm-1975	93	25	with	with	ADP
ajlm-1975	93	26	l452p	l452p	NOUN
ajlm-1975	93	27	mutation	mutation	NOUN
ajlm-1975	93	28	and	and	CCONJ
ajlm-1975	93	29	two	two	NUM
ajlm-1975	93	30	isolates	isolate	NOUN
ajlm-1975	93	31	(	(	PUNCT
ajlm-1975	93	32	5.6	5.6	NUM
ajlm-1975	93	33	%	%	NOUN
ajlm-1975	93	34	)	)	PUNCT
ajlm-1975	93	35	with	with	ADP
ajlm-1975	93	36	s450l	s450l	PROPN
ajlm-1975	93	37	mutation	mutation	NOUN
ajlm-1975	93	38	.	.	PUNCT
ajlm-1975	94	1	the	the	DET
ajlm-1975	94	2	three	three	NUM
ajlm-1975	94	3	remaining	remain	VERB
ajlm-1975	94	4	isolates	isolate	NOUN
ajlm-1975	94	5	(	(	PUNCT
ajlm-1975	94	6	8.3	8.3	NUM
ajlm-1975	94	7	%	%	NOUN
ajlm-1975	94	8	)	)	PUNCT
ajlm-1975	94	9	had	have	VERB
ajlm-1975	94	10	double	double	ADJ
ajlm-1975	94	11	rpob	rpob	ADJ
ajlm-1975	94	12	mutations	mutation	NOUN
ajlm-1975	94	13	,	,	PUNCT
ajlm-1975	94	14	including	include	VERB
ajlm-1975	94	15	one	one	NUM
ajlm-1975	94	16	isolate	isolate	NOUN
ajlm-1975	94	17	with	with	ADP
ajlm-1975	94	18	a	a	DET
ajlm-1975	94	19	combination	combination	NOUN
ajlm-1975	94	20	of	of	ADP
ajlm-1975	94	21	the	the	DET
ajlm-1975	94	22	s450l	s450l	PROPN
ajlm-1975	94	23	mutation	mutation	NOUN
ajlm-1975	94	24	(	(	PUNCT
ajlm-1975	94	25	located	locate	VERB
ajlm-1975	94	26	within	within	ADP
ajlm-1975	94	27	the	the	DET
ajlm-1975	94	28	rrdr	rrdr	NOUN
ajlm-1975	94	29	)	)	PUNCT
ajlm-1975	94	30	and	and	CCONJ
ajlm-1975	94	31	t400a	t400a	PROPN
ajlm-1975	94	32	mutation	mutation	NOUN
ajlm-1975	94	33	(	(	PUNCT
ajlm-1975	94	34	located	locate	VERB
ajlm-1975	94	35	outside	outside	ADP
ajlm-1975	94	36	the	the	DET
ajlm-1975	94	37	rrdr	rrdr	NOUN
ajlm-1975	94	38	)	)	PUNCT
ajlm-1975	94	39	,	,	PUNCT
ajlm-1975	94	40	and	and	CCONJ
ajlm-1975	94	41	two	two	NUM
ajlm-1975	94	42	isolates	isolate	NOUN
ajlm-1975	94	43	with	with	ADP
ajlm-1975	94	44	double	double	ADJ
ajlm-1975	94	45	mutations	mutation	NOUN
ajlm-1975	94	46	located	locate	VERB
ajlm-1975	94	47	within	within	ADP
ajlm-1975	94	48	the	the	DET
ajlm-1975	94	49	rrdr	rrdr	NOUN
ajlm-1975	94	50	–	–	PUNCT
ajlm-1975	94	51	one	one	NUM
ajlm-1975	94	52	with	with	ADP
ajlm-1975	94	53	d435	d435	PROPN
ajlm-1975	94	54	g	g	PROPN
ajlm-1975	94	55	and	and	CCONJ
ajlm-1975	94	56	l452p	l452p	NOUN
ajlm-1975	94	57	mutations	mutation	NOUN
ajlm-1975	94	58	and	and	CCONJ
ajlm-1975	94	59	another	another	DET
ajlm-1975	94	60	one	one	NOUN
ajlm-1975	94	61	with	with	ADP
ajlm-1975	94	62	d435y	d435y	PROPN
ajlm-1975	94	63	and	and	CCONJ
ajlm-1975	94	64	l452p	l452p	NOUN
ajlm-1975	94	65	mutations	mutation	NOUN
ajlm-1975	94	66	.	.	PUNCT
ajlm-1975	95	1	figure	figure	VERB
ajlm-1975	95	2	1	1	NUM
ajlm-1975	95	3	:	:	PUNCT
ajlm-1975	95	4	whole	whole	ADJ
ajlm-1975	95	5	-	-	PUNCT
ajlm-1975	95	6	genome	genome	NOUN
ajlm-1975	95	7	sequencing	sequencing	NOUN
ajlm-1975	95	8	results	result	NOUN
ajlm-1975	95	9	of	of	ADP
ajlm-1975	95	10	36	36	NUM
ajlm-1975	95	11	isolates	isolate	NOUN
ajlm-1975	95	12	with	with	ADP
ajlm-1975	95	13	rpob	rpob	ADJ
ajlm-1975	95	14	gene	gene	NOUN
ajlm-1975	95	15	mutations	mutation	NOUN
ajlm-1975	95	16	missed	miss	VERB
ajlm-1975	95	17	by	by	ADP
ajlm-1975	95	18	the	the	DET
ajlm-1975	95	19	genotype	genotype	NOUN
ajlm-1975	95	20	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	95	21	assay	assay	NOUN
ajlm-1975	95	22	at	at	ADP
ajlm-1975	95	23	inkosi	inkosi	PROPN
ajlm-1975	95	24	albert	albert	PROPN
ajlm-1975	95	25	luthuli	luthuli	PROPN
ajlm-1975	95	26	central	central	PROPN
ajlm-1975	95	27	hospital	hospital	PROPN
ajlm-1975	95	28	laboratory	laboratory	NOUN
ajlm-1975	95	29	in	in	ADP
ajlm-1975	95	30	kwazulu	kwazulu	PROPN
ajlm-1975	95	31	-	-	PUNCT
ajlm-1975	95	32	natal	natal	ADJ
ajlm-1975	95	33	,	,	PUNCT
ajlm-1975	95	34	south	south	PROPN
ajlm-1975	95	35	africa	africa	PROPN
ajlm-1975	95	36	,	,	PUNCT
ajlm-1975	95	37	between	between	ADP
ajlm-1975	95	38	january	january	PROPN
ajlm-1975	95	39	2014	2014	NUM
ajlm-1975	95	40	and	and	CCONJ
ajlm-1975	95	41	december	december	PROPN
ajlm-1975	95	42	2014	2014	NUM
ajlm-1975	95	43	.	.	PUNCT
ajlm-1975	96	1	the	the	DET
ajlm-1975	96	2	most	most	ADV
ajlm-1975	96	3	common	common	ADJ
ajlm-1975	96	4	isoniazid	isoniazid	NOUN
ajlm-1975	96	5	resistance	resistance	NOUN
ajlm-1975	96	6	-	-	PUNCT
ajlm-1975	96	7	conferring	confer	VERB
ajlm-1975	96	8	mutation	mutation	NOUN
ajlm-1975	96	9	was	be	AUX
ajlm-1975	96	10	the	the	DET
ajlm-1975	96	11	s315	s315	PROPN
ajlm-1975	96	12	t	t	NOUN
ajlm-1975	96	13	mutation	mutation	NOUN
ajlm-1975	96	14	,	,	PUNCT
ajlm-1975	96	15	(	(	PUNCT
ajlm-1975	96	16	29	29	NUM
ajlm-1975	96	17	isolates	isolate	NOUN
ajlm-1975	96	18	;	;	PUNCT
ajlm-1975	96	19	80.6	80.6	NUM
ajlm-1975	96	20	%	%	NOUN
ajlm-1975	96	21	)	)	PUNCT
ajlm-1975	96	22	.	.	PUNCT
ajlm-1975	97	1	this	this	PRON
ajlm-1975	97	2	was	be	AUX
ajlm-1975	97	3	followed	follow	VERB
ajlm-1975	97	4	by	by	ADP
ajlm-1975	97	5	the	the	DET
ajlm-1975	97	6	inha	inha	NOUN
ajlm-1975	97	7	promoter	promoter	NOUN
ajlm-1975	97	8	region	region	NOUN
ajlm-1975	97	9	mutation	mutation	NOUN
ajlm-1975	97	10	t-8a	t-8a	PROPN
ajlm-1975	97	11	(	(	PUNCT
ajlm-1975	97	12	15	15	NUM
ajlm-1975	97	13	isolates	isolate	NOUN
ajlm-1975	97	14	;	;	PUNCT
ajlm-1975	97	15	41.7	41.7	NUM
ajlm-1975	97	16	%	%	NOUN
ajlm-1975	97	17	)	)	PUNCT
ajlm-1975	97	18	,	,	PUNCT
ajlm-1975	97	19	which	which	PRON
ajlm-1975	97	20	was	be	AUX
ajlm-1975	97	21	found	find	VERB
ajlm-1975	97	22	together	together	ADV
ajlm-1975	97	23	with	with	ADP
ajlm-1975	97	24	the	the	DET
ajlm-1975	97	25	katg	katg	PROPN
ajlm-1975	97	26	mutation	mutation	NOUN
ajlm-1975	97	27	in	in	ADP
ajlm-1975	97	28	all	all	DET
ajlm-1975	97	29	isolates	isolate	NOUN
ajlm-1975	97	30	.	.	PUNCT
ajlm-1975	98	1	besides	besides	SCONJ
ajlm-1975	98	2	resistance	resistance	NOUN
ajlm-1975	98	3	to	to	ADP
ajlm-1975	98	4	rifampicin	rifampicin	NOUN
ajlm-1975	98	5	and	and	CCONJ
ajlm-1975	98	6	isoniazid	isoniazid	NOUN
ajlm-1975	98	7	,	,	PUNCT
ajlm-1975	98	8	most	most	ADJ
ajlm-1975	98	9	isolates	isolate	NOUN
ajlm-1975	98	10	were	be	AUX
ajlm-1975	98	11	also	also	ADV
ajlm-1975	98	12	resistant	resistant	ADJ
ajlm-1975	98	13	to	to	ADP
ajlm-1975	98	14	other	other	ADJ
ajlm-1975	98	15	first	first	ADJ
ajlm-1975	98	16	-	-	PUNCT
ajlm-1975	98	17	line	line	NOUN
ajlm-1975	98	18	drugs	drug	NOUN
ajlm-1975	98	19	,	,	PUNCT
ajlm-1975	98	20	including	include	VERB
ajlm-1975	98	21	pyrazinamide	pyrazinamide	NOUN
ajlm-1975	98	22	(	(	PUNCT
ajlm-1975	98	23	25	25	NUM
ajlm-1975	98	24	isolates	isolate	NOUN
ajlm-1975	98	25	;	;	PUNCT
ajlm-1975	98	26	69.4	69.4	NUM
ajlm-1975	98	27	%	%	NOUN
ajlm-1975	98	28	)	)	PUNCT
ajlm-1975	98	29	,	,	PUNCT
ajlm-1975	98	30	ethambutol	ethambutol	X
ajlm-1975	98	31	(	(	PUNCT
ajlm-1975	98	32	30	30	NUM
ajlm-1975	98	33	;	;	PUNCT
ajlm-1975	98	34	83.3	83.3	NUM
ajlm-1975	98	35	%	%	NOUN
ajlm-1975	98	36	)	)	PUNCT
ajlm-1975	98	37	,	,	PUNCT
ajlm-1975	98	38	and	and	CCONJ
ajlm-1975	98	39	streptomycin	streptomycin	PROPN
ajlm-1975	98	40	(	(	PUNCT
ajlm-1975	98	41	25	25	NUM
ajlm-1975	98	42	;	;	PUNCT
ajlm-1975	98	43	69.4	69.4	NUM
ajlm-1975	98	44	%	%	NOUN
ajlm-1975	98	45	)	)	PUNCT
ajlm-1975	98	46	.	.	PUNCT
ajlm-1975	99	1	some	some	DET
ajlm-1975	99	2	isolates	isolate	NOUN
ajlm-1975	99	3	were	be	AUX
ajlm-1975	99	4	also	also	ADV
ajlm-1975	99	5	resistant	resistant	ADJ
ajlm-1975	99	6	to	to	ADP
ajlm-1975	99	7	second	second	ADJ
ajlm-1975	99	8	-	-	PUNCT
ajlm-1975	99	9	line	line	NOUN
ajlm-1975	99	10	drugs	drug	NOUN
ajlm-1975	99	11	,	,	PUNCT
ajlm-1975	99	12	including	include	VERB
ajlm-1975	99	13	the	the	DET
ajlm-1975	99	14	second	second	ADJ
ajlm-1975	99	15	-	-	PUNCT
ajlm-1975	99	16	line	line	NOUN
ajlm-1975	99	17	injectable	injectable	ADJ
ajlm-1975	99	18	agents	agent	NOUN
ajlm-1975	99	19	(	(	PUNCT
ajlm-1975	99	20	three	three	NUM
ajlm-1975	99	21	isolates	isolate	NOUN
ajlm-1975	99	22	;	;	PUNCT
ajlm-1975	99	23	8.3	8.3	NUM
ajlm-1975	99	24	%	%	NOUN
ajlm-1975	99	25	)	)	PUNCT
ajlm-1975	99	26	,	,	PUNCT
ajlm-1975	99	27	fluoroquinolones	fluoroquinolone	NOUN
ajlm-1975	99	28	(	(	PUNCT
ajlm-1975	99	29	six	six	NUM
ajlm-1975	99	30	;	;	PUNCT
ajlm-1975	99	31	16.7	16.7	NUM
ajlm-1975	99	32	%	%	NOUN
ajlm-1975	99	33	)	)	PUNCT
ajlm-1975	99	34	,	,	PUNCT
ajlm-1975	99	35	and	and	CCONJ
ajlm-1975	99	36	ethionamide	ethionamide	NOUN
ajlm-1975	99	37	(	(	PUNCT
ajlm-1975	99	38	18	18	NUM
ajlm-1975	99	39	;	;	PUNCT
ajlm-1975	99	40	50.0	50.0	NUM
ajlm-1975	99	41	%	%	NOUN
ajlm-1975	99	42	)	)	PUNCT
ajlm-1975	99	43	.	.	PUNCT
ajlm-1975	100	1	one	one	NUM
ajlm-1975	100	2	isolate	isolate	NOUN
ajlm-1975	100	3	had	have	VERB
ajlm-1975	100	4	an	an	DET
ajlm-1975	100	5	insertion	insertion	NOUN
ajlm-1975	100	6	in	in	ADP
ajlm-1975	100	7	the	the	DET
ajlm-1975	100	8	mmpr5	mmpr5	NOUN
ajlm-1975	100	9	gene	gene	NOUN
ajlm-1975	100	10	,	,	PUNCT
ajlm-1975	100	11	which	which	PRON
ajlm-1975	100	12	is	be	AUX
ajlm-1975	100	13	associated	associate	VERB
ajlm-1975	100	14	with	with	ADP
ajlm-1975	100	15	bedaquiline	bedaquiline	NOUN
ajlm-1975	100	16	and	and	CCONJ
ajlm-1975	100	17	clofazimine	clofazimine	ADJ
ajlm-1975	100	18	resistance	resistance	NOUN
ajlm-1975	100	19	.	.	PUNCT
ajlm-1975	101	1	among	among	ADP
ajlm-1975	101	2	the	the	DET
ajlm-1975	101	3	16	16	NUM
ajlm-1975	101	4	isolates	isolate	NOUN
ajlm-1975	101	5	with	with	ADP
ajlm-1975	101	6	an	an	DET
ajlm-1975	101	7	i491f	i491f	PROPN
ajlm-1975	101	8	rpob	rpob	PROPN
ajlm-1975	101	9	mutation	mutation	NOUN
ajlm-1975	101	10	,	,	PUNCT
ajlm-1975	101	11	one	one	NUM
ajlm-1975	101	12	belonged	belong	VERB
ajlm-1975	101	13	to	to	ADP
ajlm-1975	101	14	sub	sub	VERB
ajlm-1975	101	15	-	-	NOUN
ajlm-1975	101	16	lineage	lineage	NOUN
ajlm-1975	101	17	2.2.1	2.2.1	NUM
ajlm-1975	101	18	,	,	PUNCT
ajlm-1975	101	19	while	while	SCONJ
ajlm-1975	101	20	the	the	DET
ajlm-1975	101	21	remaining	remain	VERB
ajlm-1975	101	22	15	15	NUM
ajlm-1975	101	23	isolates	isolate	NOUN
ajlm-1975	101	24	belonged	belong	VERB
ajlm-1975	101	25	to	to	ADP
ajlm-1975	101	26	three	three	NUM
ajlm-1975	101	27	distinct	distinct	ADJ
ajlm-1975	101	28	sub	sub	NOUN
ajlm-1975	101	29	-	-	NOUN
ajlm-1975	101	30	lineages	lineage	NOUN
ajlm-1975	101	31	of	of	ADP
ajlm-1975	101	32	lineage	lineage	NOUN
ajlm-1975	101	33	4	4	NUM
ajlm-1975	101	34	.	.	PUNCT
ajlm-1975	101	35	of	of	ADP
ajlm-1975	101	36	these	these	DET
ajlm-1975	101	37	15	15	NUM
ajlm-1975	101	38	isolates	isolate	NOUN
ajlm-1975	101	39	,	,	PUNCT
ajlm-1975	101	40	three	three	NUM
ajlm-1975	101	41	isolates	isolate	NOUN
ajlm-1975	101	42	each	each	PRON
ajlm-1975	101	43	had	have	VERB
ajlm-1975	101	44	unique	unique	ADJ
ajlm-1975	101	45	mutation	mutation	NOUN
ajlm-1975	101	46	patterns	pattern	NOUN
ajlm-1975	101	47	,	,	PUNCT
ajlm-1975	101	48	while	while	SCONJ
ajlm-1975	101	49	12	12	NUM
ajlm-1975	101	50	clustered	cluster	VERB
ajlm-1975	101	51	into	into	ADP
ajlm-1975	101	52	two	two	NUM
ajlm-1975	101	53	groups	group	NOUN
ajlm-1975	101	54	based	base	VERB
ajlm-1975	101	55	on	on	ADP
ajlm-1975	101	56	mutation	mutation	NOUN
ajlm-1975	101	57	patterns	pattern	NOUN
ajlm-1975	101	58	.	.	PUNCT
ajlm-1975	102	1	one	one	NUM
ajlm-1975	102	2	group	group	NOUN
ajlm-1975	102	3	of	of	ADP
ajlm-1975	102	4	six	six	NUM
ajlm-1975	102	5	isolates	isolate	NOUN
ajlm-1975	102	6	belonging	belong	VERB
ajlm-1975	102	7	to	to	ADP
ajlm-1975	102	8	the	the	DET
ajlm-1975	102	9	4.4.1.1	4.4.1.1	NUM
ajlm-1975	102	10	sub	sub	NOUN
ajlm-1975	102	11	-	-	ADJ
ajlm-1975	102	12	lineage	lineage	NOUN
ajlm-1975	102	13	carried	carry	VERB
ajlm-1975	102	14	katg	katg	NOUN
ajlm-1975	102	15	s315	s315	PROPN
ajlm-1975	102	16	t	t	PROPN
ajlm-1975	102	17	,	,	PUNCT
ajlm-1975	102	18	pnca	pnca	PROPN
ajlm-1975	102	19	h51d	h51d	PROPN
ajlm-1975	102	20	,	,	PUNCT
ajlm-1975	102	21	embb	embb	ADJ
ajlm-1975	102	22	m306i	m306i	PROPN
ajlm-1975	102	23	,	,	PUNCT
ajlm-1975	102	24	and	and	CCONJ
ajlm-1975	102	25	rpsl	rpsl	VERB
ajlm-1975	102	26	k43r	k43r	PROPN
ajlm-1975	102	27	,	,	PUNCT
ajlm-1975	102	28	which	which	PRON
ajlm-1975	102	29	confer	confer	VERB
ajlm-1975	102	30	resistance	resistance	NOUN
ajlm-1975	102	31	to	to	ADP
ajlm-1975	102	32	isoniazid	isoniazid	NOUN
ajlm-1975	102	33	,	,	PUNCT
ajlm-1975	102	34	pyrazinamide	pyrazinamide	NOUN
ajlm-1975	102	35	,	,	PUNCT
ajlm-1975	102	36	ethambutol	ethambutol	ADJ
ajlm-1975	102	37	,	,	PUNCT
ajlm-1975	102	38	and	and	CCONJ
ajlm-1975	102	39	streptomycin	streptomycin	PROPN
ajlm-1975	102	40	.	.	PUNCT
ajlm-1975	103	1	another	another	DET
ajlm-1975	103	2	group	group	NOUN
ajlm-1975	103	3	of	of	ADP
ajlm-1975	103	4	six	six	NUM
ajlm-1975	103	5	isolates	isolate	NOUN
ajlm-1975	103	6	belonging	belong	VERB
ajlm-1975	103	7	to	to	ADP
ajlm-1975	103	8	sub	sub	ADJ
ajlm-1975	103	9	-	-	NOUN
ajlm-1975	103	10	lineage	lineage	ADJ
ajlm-1975	103	11	4.3.3	4.3.3	NUM
ajlm-1975	103	12	had	have	VERB
ajlm-1975	103	13	mutations	mutation	NOUN
ajlm-1975	103	14	conferring	confer	VERB
ajlm-1975	103	15	isoniazid	isoniazid	NOUN
ajlm-1975	103	16	(	(	PUNCT
ajlm-1975	103	17	inha	inha	NOUN
ajlm-1975	103	18	[	[	X
ajlm-1975	103	19	fabg1	fabg1	NOUN
ajlm-1975	103	20	8	8	NUM
ajlm-1975	103	21	t	t	NOUN
ajlm-1975	103	22	>	>	X
ajlm-1975	103	23	a	a	X
ajlm-1975	103	24	]	]	PUNCT
ajlm-1975	103	25	plus	plus	CCONJ
ajlm-1975	103	26	katg	katg	PROPN
ajlm-1975	103	27	s315	s315	PROPN
ajlm-1975	103	28	t	t	PROPN
ajlm-1975	103	29	)	)	PUNCT
ajlm-1975	103	30	,	,	PUNCT
ajlm-1975	103	31	pyrazinamide	pyrazinamide	NOUN
ajlm-1975	103	32	(	(	PUNCT
ajlm-1975	103	33	pnca	pnca	PROPN
ajlm-1975	103	34	g132a	g132a	PROPN
ajlm-1975	103	35	)	)	PUNCT
ajlm-1975	103	36	,	,	PUNCT
ajlm-1975	103	37	ethambutol	ethambutol	X
ajlm-1975	103	38	(	(	PUNCT
ajlm-1975	103	39	embb	embb	PROPN
ajlm-1975	103	40	m306v	m306v	PROPN
ajlm-1975	103	41	)	)	PUNCT
ajlm-1975	103	42	,	,	PUNCT
ajlm-1975	103	43	streptomycin	streptomycin	PROPN
ajlm-1975	103	44	(	(	PUNCT
ajlm-1975	103	45	gidb	gidb	NOUN
ajlm-1975	103	46	130bp	130bp	ADJ
ajlm-1975	103	47	deletion	deletion	NOUN
ajlm-1975	103	48	)	)	PUNCT
ajlm-1975	103	49	,	,	PUNCT
ajlm-1975	103	50	and	and	CCONJ
ajlm-1975	103	51	ethionamide	ethionamide	NOUN
ajlm-1975	103	52	(	(	PUNCT
ajlm-1975	103	53	etha	etha	PROPN
ajlm-1975	103	54	11a	11a	PROPN
ajlm-1975	103	55	>	>	SYM
ajlm-1975	103	56	g	g	PROPN
ajlm-1975	103	57	)	)	PUNCT
ajlm-1975	103	58	resistance	resistance	NOUN
ajlm-1975	103	59	.	.	PUNCT
ajlm-1975	104	1	the	the	DET
ajlm-1975	104	2	12	12	NUM
ajlm-1975	104	3	isolates	isolate	NOUN
ajlm-1975	104	4	carrying	carry	VERB
ajlm-1975	104	5	a	a	DET
ajlm-1975	104	6	single	single	ADJ
ajlm-1975	104	7	l452p	l452p	NOUN
ajlm-1975	104	8	mutation	mutation	NOUN
ajlm-1975	104	9	also	also	ADV
ajlm-1975	104	10	belonged	belong	VERB
ajlm-1975	104	11	to	to	PART
ajlm-1975	104	12	lineage	lineage	VERB
ajlm-1975	104	13	4	4	NUM
ajlm-1975	104	14	.	.	PUNCT
ajlm-1975	105	1	among	among	ADP
ajlm-1975	105	2	the	the	DET
ajlm-1975	105	3	12	12	NUM
ajlm-1975	105	4	isolates	isolate	NOUN
ajlm-1975	105	5	,	,	PUNCT
ajlm-1975	105	6	there	there	PRON
ajlm-1975	105	7	were	be	VERB
ajlm-1975	105	8	two	two	NUM
ajlm-1975	105	9	clusters	cluster	NOUN
ajlm-1975	105	10	with	with	ADP
ajlm-1975	105	11	common	common	ADJ
ajlm-1975	105	12	resistance	resistance	NOUN
ajlm-1975	105	13	-	-	PUNCT
ajlm-1975	105	14	conferring	confer	VERB
ajlm-1975	105	15	mutations	mutation	NOUN
ajlm-1975	105	16	.	.	PUNCT
ajlm-1975	106	1	the	the	DET
ajlm-1975	106	2	first	first	ADJ
ajlm-1975	106	3	group	group	NOUN
ajlm-1975	106	4	consisted	consist	VERB
ajlm-1975	106	5	of	of	ADP
ajlm-1975	106	6	eight	eight	NUM
ajlm-1975	106	7	isolates	isolate	NOUN
ajlm-1975	106	8	belonging	belong	VERB
ajlm-1975	106	9	to	to	ADP
ajlm-1975	106	10	sub	sub	NOUN
ajlm-1975	106	11	-	-	NOUN
ajlm-1975	106	12	lineage	lineage	ADJ
ajlm-1975	106	13	4.3.3	4.3.3	NUM
ajlm-1975	106	14	and	and	CCONJ
ajlm-1975	106	15	had	have	VERB
ajlm-1975	106	16	the	the	DET
ajlm-1975	106	17	inha	inha	NOUN
ajlm-1975	106	18	fabg1c.-8	fabg1c.-8	NOUN
ajlm-1975	106	19	t	t	PROPN
ajlm-1975	106	20	>	>	X
ajlm-1975	106	21	a	a	DET
ajlm-1975	106	22	plus	plus	ADJ
ajlm-1975	106	23	katg	katg	NOUN
ajlm-1975	106	24	s315	s315	PROPN
ajlm-1975	106	25	t	t	PROPN
ajlm-1975	106	26	isoniazid	isoniazid	NOUN
ajlm-1975	106	27	resistance	resistance	NOUN
ajlm-1975	106	28	-	-	PUNCT
ajlm-1975	106	29	conferring	confer	VERB
ajlm-1975	106	30	mutations	mutation	NOUN
ajlm-1975	106	31	,	,	PUNCT
ajlm-1975	106	32	as	as	ADV
ajlm-1975	106	33	well	well	ADV
ajlm-1975	106	34	as	as	ADP
ajlm-1975	106	35	the	the	DET
ajlm-1975	106	36	pnca	pnca	PROPN
ajlm-1975	106	37	456_457	456_457	PROPN
ajlm-1975	106	38	c	c	NOUN
ajlm-1975	106	39	insertion	insertion	NOUN
ajlm-1975	106	40	(	(	PUNCT
ajlm-1975	106	41	pyrazinamide	pyrazinamide	NOUN
ajlm-1975	106	42	resistance	resistance	NOUN
ajlm-1975	106	43	)	)	PUNCT
ajlm-1975	106	44	,	,	PUNCT
ajlm-1975	106	45	embb	embb	PROPN
ajlm-1975	106	46	m306v	m306v	PROPN
ajlm-1975	106	47	(	(	PUNCT
ajlm-1975	106	48	ethambutol	ethambutol	NOUN
ajlm-1975	106	49	resistance	resistance	NOUN
ajlm-1975	106	50	)	)	PUNCT
ajlm-1975	106	51	,	,	PUNCT
ajlm-1975	106	52	etha_11a	etha_11a	PROPN
ajlm-1975	106	53	>	>	X
ajlm-1975	106	54	g	g	PROPN
ajlm-1975	106	55	(	(	PUNCT
ajlm-1975	106	56	ethionamide	ethionamide	PROPN
ajlm-1975	106	57	resistance	resistance	NOUN
ajlm-1975	106	58	)	)	PUNCT
ajlm-1975	106	59	,	,	PUNCT
ajlm-1975	106	60	and	and	CCONJ
ajlm-1975	106	61	the	the	DET
ajlm-1975	106	62	gidb	gidb	NOUN
ajlm-1975	106	63	130bp	130bp	ADJ
ajlm-1975	106	64	deletion	deletion	NOUN
ajlm-1975	106	65	(	(	PUNCT
ajlm-1975	106	66	streptomycin	streptomycin	NOUN
ajlm-1975	106	67	resistance	resistance	NOUN
ajlm-1975	106	68	)	)	PUNCT
ajlm-1975	106	69	mutations	mutation	NOUN
ajlm-1975	106	70	.	.	PUNCT
ajlm-1975	107	1	the	the	DET
ajlm-1975	107	2	second	second	ADJ
ajlm-1975	107	3	group	group	NOUN
ajlm-1975	107	4	consisted	consist	VERB
ajlm-1975	107	5	of	of	ADP
ajlm-1975	107	6	three	three	NUM
ajlm-1975	107	7	isolates	isolate	NOUN
ajlm-1975	107	8	belonging	belong	VERB
ajlm-1975	107	9	to	to	ADP
ajlm-1975	107	10	sub	sub	ADJ
ajlm-1975	107	11	-	-	NOUN
ajlm-1975	107	12	lineage	lineage	ADJ
ajlm-1975	107	13	4.4.1.1.1	4.4.1.1.1	NOUN
ajlm-1975	107	14	and	and	CCONJ
ajlm-1975	107	15	carrying	carry	VERB
ajlm-1975	107	16	katg	katg	NOUN
ajlm-1975	107	17	s315	s315	PROPN
ajlm-1975	107	18	t	t	PROPN
ajlm-1975	107	19	and	and	CCONJ
ajlm-1975	107	20	embb	embb	ADJ
ajlm-1975	107	21	m306i	m306i	PROPN
ajlm-1975	107	22	mutations	mutation	NOUN
ajlm-1975	107	23	for	for	ADP
ajlm-1975	107	24	isoniazid	isoniazid	NOUN
ajlm-1975	107	25	and	and	CCONJ
ajlm-1975	107	26	ethambutol	ethambutol	ADJ
ajlm-1975	107	27	resistance	resistance	NOUN
ajlm-1975	107	28	.	.	PUNCT
ajlm-1975	108	1	discussion	discussion	NOUN
ajlm-1975	108	2	in	in	ADP
ajlm-1975	108	3	this	this	DET
ajlm-1975	108	4	study	study	NOUN
ajlm-1975	108	5	,	,	PUNCT
ajlm-1975	108	6	almost	almost	ADV
ajlm-1975	108	7	29	29	NUM
ajlm-1975	108	8	%	%	NOUN
ajlm-1975	108	9	of	of	ADP
ajlm-1975	108	10	the	the	DET
ajlm-1975	108	11	isoniazid	isoniazid	NOUN
ajlm-1975	108	12	mono	mono	NOUN
ajlm-1975	108	13	-	-	PUNCT
ajlm-1975	108	14	resistant	resistant	ADJ
ajlm-1975	108	15	tuberculosis	tuberculosis	NOUN
ajlm-1975	108	16	cases	case	NOUN
ajlm-1975	108	17	detected	detect	VERB
ajlm-1975	108	18	using	use	VERB
ajlm-1975	108	19	the	the	DET
ajlm-1975	108	20	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	108	21	assay	assay	NOUN
ajlm-1975	108	22	were	be	AUX
ajlm-1975	108	23	mdr	mdr	PROPN
ajlm-1975	108	24	-	-	ADJ
ajlm-1975	108	25	tb	tb	ADP
ajlm-1975	108	26	cases	case	NOUN
ajlm-1975	108	27	.	.	PUNCT
ajlm-1975	109	1	this	this	PRON
ajlm-1975	109	2	led	lead	VERB
ajlm-1975	109	3	to	to	ADP
ajlm-1975	109	4	significant	significant	ADJ
ajlm-1975	109	5	delays	delay	NOUN
ajlm-1975	109	6	in	in	ADP
ajlm-1975	109	7	the	the	DET
ajlm-1975	109	8	initiation	initiation	NOUN
ajlm-1975	109	9	of	of	ADP
ajlm-1975	109	10	dr	dr	PROPN
ajlm-1975	109	11	-	-	PUNCT
ajlm-1975	109	12	tb	tb	NOUN
ajlm-1975	109	13	treatment	treatment	NOUN
ajlm-1975	109	14	.	.	PUNCT
ajlm-1975	110	1	the	the	DET
ajlm-1975	110	2	main	main	ADJ
ajlm-1975	110	3	cause	cause	NOUN
ajlm-1975	110	4	of	of	ADP
ajlm-1975	110	5	rifampicin	rifampicin	VERB
ajlm-1975	110	6	resistance	resistance	NOUN
ajlm-1975	110	7	missed	miss	VERB
ajlm-1975	110	8	by	by	ADP
ajlm-1975	110	9	the	the	DET
ajlm-1975	110	10	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	110	11	assay	assay	NOUN
ajlm-1975	110	12	was	be	AUX
ajlm-1975	110	13	the	the	DET
ajlm-1975	110	14	presence	presence	NOUN
ajlm-1975	110	15	of	of	ADP
ajlm-1975	110	16	mutations	mutation	NOUN
ajlm-1975	110	17	outside	outside	ADP
ajlm-1975	110	18	the	the	DET
ajlm-1975	110	19	rrdr	rrdr	NOUN
ajlm-1975	110	20	(	(	PUNCT
ajlm-1975	110	21	mainly	mainly	ADV
ajlm-1975	110	22	i491f	i491f	PROPN
ajlm-1975	110	23	)	)	PUNCT
ajlm-1975	110	24	,	,	PUNCT
ajlm-1975	110	25	as	as	ADV
ajlm-1975	110	26	well	well	ADV
ajlm-1975	110	27	as	as	ADP
ajlm-1975	110	28	the	the	DET
ajlm-1975	110	29	l452p	l452p	PROPN
ajlm-1975	110	30	rpob	rpob	PROPN
ajlm-1975	110	31	mutation	mutation	NOUN
ajlm-1975	110	32	.	.	PUNCT
ajlm-1975	111	1	mutations	mutation	NOUN
ajlm-1975	111	2	outside	outside	ADP
ajlm-1975	111	3	the	the	DET
ajlm-1975	111	4	rrdr	rrdr	NOUN
ajlm-1975	111	5	are	be	AUX
ajlm-1975	111	6	not	not	PART
ajlm-1975	111	7	detected	detect	VERB
ajlm-1975	111	8	by	by	ADP
ajlm-1975	111	9	the	the	DET
ajlm-1975	111	10	currently	currently	ADV
ajlm-1975	111	11	used	use	VERB
ajlm-1975	111	12	who	who	PRON
ajlm-1975	111	13	-	-	PUNCT
ajlm-1975	111	14	endorsed	endorse	VERB
ajlm-1975	111	15	rapid	rapid	ADJ
ajlm-1975	111	16	molecular	molecular	ADJ
ajlm-1975	111	17	assays	assay	NOUN
ajlm-1975	111	18	,	,	PUNCT
ajlm-1975	111	19	while	while	SCONJ
ajlm-1975	111	20	the	the	DET
ajlm-1975	111	21	l452p	l452p	NOUN
ajlm-1975	111	22	mutations	mutation	NOUN
ajlm-1975	111	23	were	be	AUX
ajlm-1975	111	24	missed	miss	VERB
ajlm-1975	111	25	by	by	ADP
ajlm-1975	111	26	the	the	DET
ajlm-1975	111	27	previous	previous	ADJ
ajlm-1975	111	28	version	version	NOUN
ajlm-1975	111	29	of	of	ADP
ajlm-1975	111	30	the	the	DET
ajlm-1975	111	31	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	111	32	assay	assay	NOUN
ajlm-1975	111	33	.	.	PUNCT
ajlm-1975	112	1	importantly	importantly	ADV
ajlm-1975	112	2	,	,	PUNCT
ajlm-1975	112	3	isolates	isolate	NOUN
ajlm-1975	112	4	carrying	carry	VERB
ajlm-1975	112	5	these	these	DET
ajlm-1975	112	6	mutations	mutation	NOUN
ajlm-1975	112	7	were	be	AUX
ajlm-1975	112	8	also	also	ADV
ajlm-1975	112	9	resistant	resistant	ADJ
ajlm-1975	112	10	to	to	ADP
ajlm-1975	112	11	other	other	ADJ
ajlm-1975	112	12	first	first	ADJ
ajlm-1975	112	13	-	-	PUNCT
ajlm-1975	112	14	line	line	NOUN
ajlm-1975	112	15	anti	anti	ADJ
ajlm-1975	112	16	-	-	ADJ
ajlm-1975	112	17	tuberculosis	tuberculosis	ADJ
ajlm-1975	112	18	drugs	drug	NOUN
ajlm-1975	112	19	whose	whose	DET
ajlm-1975	112	20	resistance	resistance	NOUN
ajlm-1975	112	21	is	be	AUX
ajlm-1975	112	22	not	not	PART
ajlm-1975	112	23	routinely	routinely	ADV
ajlm-1975	112	24	tested	test	VERB
ajlm-1975	112	25	in	in	ADP
ajlm-1975	112	26	tuberculosis	tuberculosis	NOUN
ajlm-1975	112	27	patients	patient	NOUN
ajlm-1975	112	28	globally	globally	ADV
ajlm-1975	112	29	,	,	PUNCT
ajlm-1975	112	30	and	and	CCONJ
ajlm-1975	112	31	the	the	DET
ajlm-1975	112	32	isolates	isolate	NOUN
ajlm-1975	112	33	also	also	ADV
ajlm-1975	112	34	clustered	cluster	VERB
ajlm-1975	112	35	into	into	ADP
ajlm-1975	112	36	distinct	distinct	ADJ
ajlm-1975	112	37	groups	group	NOUN
ajlm-1975	112	38	with	with	ADP
ajlm-1975	112	39	unique	unique	ADJ
ajlm-1975	112	40	mutation	mutation	NOUN
ajlm-1975	112	41	profiles	profile	NOUN
ajlm-1975	112	42	.	.	PUNCT
ajlm-1975	113	1	the	the	DET
ajlm-1975	113	2	rpob	rpob	PROPN
ajlm-1975	113	3	l452p	l452p	PROPN
ajlm-1975	113	4	mutation	mutation	NOUN
ajlm-1975	113	5	was	be	AUX
ajlm-1975	113	6	left	leave	VERB
ajlm-1975	113	7	out	out	ADP
ajlm-1975	113	8	of	of	ADP
ajlm-1975	113	9	the	the	DET
ajlm-1975	113	10	earlier	early	ADJ
ajlm-1975	113	11	version	version	NOUN
ajlm-1975	113	12	(	(	PUNCT
ajlm-1975	113	13	version	version	NOUN
ajlm-1975	113	14	2	2	NUM
ajlm-1975	113	15	,	,	PUNCT
ajlm-1975	113	16	released	release	VERB
ajlm-1975	113	17	in	in	ADP
ajlm-1975	113	18	2011	2011	NUM
ajlm-1975	113	19	)	)	PUNCT
ajlm-1975	113	20	of	of	ADP
ajlm-1975	113	21	the	the	DET
ajlm-1975	113	22	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	113	23	assay	assay	NOUN
ajlm-1975	113	24	as	as	SCONJ
ajlm-1975	113	25	it	it	PRON
ajlm-1975	113	26	was	be	AUX
ajlm-1975	113	27	thought	think	VERB
ajlm-1975	113	28	to	to	PART
ajlm-1975	113	29	be	be	AUX
ajlm-1975	113	30	clinically	clinically	ADV
ajlm-1975	113	31	insignificant.18	insignificant.18	VERB
ajlm-1975	113	32	this	this	PRON
ajlm-1975	113	33	was	be	AUX
ajlm-1975	113	34	later	later	ADV
ajlm-1975	113	35	corrected	correct	VERB
ajlm-1975	113	36	in	in	ADP
ajlm-1975	113	37	an	an	DET
ajlm-1975	113	38	updated	update	VERB
ajlm-1975	113	39	version	version	NOUN
ajlm-1975	113	40	of	of	ADP
ajlm-1975	113	41	the	the	DET
ajlm-1975	113	42	assay	assay	NOUN
ajlm-1975	113	43	launched	launch	VERB
ajlm-1975	113	44	in	in	ADP
ajlm-1975	113	45	2014.18,19	2014.18,19	NUM
ajlm-1975	113	46	at	at	ADP
ajlm-1975	113	47	the	the	DET
ajlm-1975	113	48	time	time	NOUN
ajlm-1975	113	49	of	of	ADP
ajlm-1975	113	50	this	this	DET
ajlm-1975	113	51	study	study	NOUN
ajlm-1975	113	52	,	,	PUNCT
ajlm-1975	113	53	the	the	DET
ajlm-1975	113	54	older	old	ADJ
ajlm-1975	113	55	version	version	NOUN
ajlm-1975	113	56	2	2	NUM
ajlm-1975	113	57	was	be	AUX
ajlm-1975	113	58	still	still	ADV
ajlm-1975	113	59	in	in	ADP
ajlm-1975	113	60	use	use	NOUN
ajlm-1975	113	61	,	,	PUNCT
ajlm-1975	113	62	hence	hence	ADV
ajlm-1975	113	63	the	the	DET
ajlm-1975	113	64	discordant	discordant	ADJ
ajlm-1975	113	65	rifampicin	rifampicin	VERB
ajlm-1975	113	66	results	result	NOUN
ajlm-1975	113	67	between	between	ADP
ajlm-1975	113	68	the	the	DET
ajlm-1975	113	69	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	113	70	assay	assay	NOUN
ajlm-1975	113	71	and	and	CCONJ
ajlm-1975	113	72	the	the	DET
ajlm-1975	113	73	phenotypic	phenotypic	NOUN
ajlm-1975	113	74	assay	assay	VERB
ajlm-1975	113	75	in	in	ADP
ajlm-1975	113	76	isolates	isolate	NOUN
ajlm-1975	113	77	harbouring	harbour	VERB
ajlm-1975	113	78	this	this	DET
ajlm-1975	113	79	mutation	mutation	NOUN
ajlm-1975	113	80	.	.	PUNCT
ajlm-1975	114	1	the	the	DET
ajlm-1975	114	2	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	114	3	assay	assay	NOUN
ajlm-1975	114	4	may	may	AUX
ajlm-1975	114	5	also	also	ADV
ajlm-1975	114	6	miss	miss	VERB
ajlm-1975	114	7	heteroresistance	heteroresistance	NOUN
ajlm-1975	114	8	.	.	PUNCT
ajlm-1975	115	1	one	one	NUM
ajlm-1975	115	2	belgian	belgian	ADJ
ajlm-1975	115	3	study	study	NOUN
ajlm-1975	115	4	from	from	ADP
ajlm-1975	115	5	2019	2019	NUM
ajlm-1975	115	6	found	find	VERB
ajlm-1975	115	7	that	that	SCONJ
ajlm-1975	115	8	the	the	DET
ajlm-1975	115	9	limit	limit	NOUN
ajlm-1975	115	10	of	of	ADP
ajlm-1975	115	11	detection	detection	NOUN
ajlm-1975	115	12	of	of	ADP
ajlm-1975	115	13	rifampicin	rifampicin	VERB
ajlm-1975	115	14	heteroresistance	heteroresistance	NOUN
ajlm-1975	115	15	was	be	AUX
ajlm-1975	115	16	5	5	NUM
ajlm-1975	115	17	%	%	NOUN
ajlm-1975	115	18	–	–	PUNCT
ajlm-1975	115	19	10%.6	10%.6	NOUN
ajlm-1975	115	20	this	this	PRON
ajlm-1975	115	21	may	may	AUX
ajlm-1975	115	22	explain	explain	VERB
ajlm-1975	115	23	the	the	DET
ajlm-1975	115	24	other	other	ADJ
ajlm-1975	115	25	rrdr	rrdr	ADJ
ajlm-1975	115	26	mutations	mutation	NOUN
ajlm-1975	115	27	missed	miss	VERB
ajlm-1975	115	28	by	by	ADP
ajlm-1975	115	29	the	the	DET
ajlm-1975	115	30	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	115	31	assay	assay	NOUN
ajlm-1975	115	32	in	in	ADP
ajlm-1975	115	33	this	this	DET
ajlm-1975	115	34	study	study	NOUN
ajlm-1975	115	35	.	.	PUNCT
ajlm-1975	116	1	notably	notably	ADV
ajlm-1975	116	2	,	,	PUNCT
ajlm-1975	116	3	among	among	ADP
ajlm-1975	116	4	isolates	isolate	NOUN
ajlm-1975	116	5	that	that	PRON
ajlm-1975	116	6	had	have	VERB
ajlm-1975	116	7	an	an	DET
ajlm-1975	116	8	xpert	xpert	PROPN
ajlm-1975	116	9	result	result	NOUN
ajlm-1975	116	10	and	and	CCONJ
ajlm-1975	116	11	had	have	VERB
ajlm-1975	116	12	the	the	DET
ajlm-1975	116	13	l452p	l452p	NOUN
ajlm-1975	116	14	mutation	mutation	NOUN
ajlm-1975	116	15	as	as	SCONJ
ajlm-1975	116	16	detected	detect	VERB
ajlm-1975	116	17	by	by	ADP
ajlm-1975	116	18	whole	whole	ADJ
ajlm-1975	116	19	-	-	PUNCT
ajlm-1975	116	20	genome	genome	NOUN
ajlm-1975	116	21	sequencing	sequencing	NOUN
ajlm-1975	116	22	,	,	PUNCT
ajlm-1975	116	23	the	the	DET
ajlm-1975	116	24	xpert	xpert	PROPN
ajlm-1975	116	25	assay	assay	PROPN
ajlm-1975	116	26	detected	detect	VERB
ajlm-1975	116	27	rifampicin	rifampicin	VERB
ajlm-1975	116	28	resistance	resistance	NOUN
ajlm-1975	116	29	.	.	PUNCT
ajlm-1975	117	1	mutations	mutation	NOUN
ajlm-1975	117	2	outside	outside	ADP
ajlm-1975	117	3	the	the	DET
ajlm-1975	117	4	rrdr	rrdr	NOUN
ajlm-1975	117	5	were	be	AUX
ajlm-1975	117	6	found	find	VERB
ajlm-1975	117	7	in	in	ADP
ajlm-1975	117	8	just	just	ADV
ajlm-1975	117	9	over	over	ADP
ajlm-1975	117	10	half	half	NOUN
ajlm-1975	117	11	(	(	PUNCT
ajlm-1975	117	12	19/36	19/36	NUM
ajlm-1975	117	13	)	)	PUNCT
ajlm-1975	117	14	of	of	ADP
ajlm-1975	117	15	isolates	isolate	NOUN
ajlm-1975	117	16	with	with	ADP
ajlm-1975	117	17	discordant	discordant	ADJ
ajlm-1975	117	18	results	result	NOUN
ajlm-1975	117	19	that	that	PRON
ajlm-1975	117	20	were	be	AUX
ajlm-1975	117	21	tested	test	VERB
ajlm-1975	117	22	using	use	VERB
ajlm-1975	117	23	whole	whole	ADJ
ajlm-1975	117	24	-	-	PUNCT
ajlm-1975	117	25	genome	genome	NOUN
ajlm-1975	117	26	sequencing	sequencing	NOUN
ajlm-1975	117	27	.	.	PUNCT
ajlm-1975	118	1	if	if	SCONJ
ajlm-1975	118	2	we	we	PRON
ajlm-1975	118	3	assume	assume	VERB
ajlm-1975	118	4	that	that	SCONJ
ajlm-1975	118	5	this	this	DET
ajlm-1975	118	6	proportion	proportion	NOUN
ajlm-1975	118	7	is	be	AUX
ajlm-1975	118	8	representative	representative	NOUN
ajlm-1975	118	9	of	of	ADP
ajlm-1975	118	10	the	the	DET
ajlm-1975	118	11	whole	whole	ADJ
ajlm-1975	118	12	145	145	NUM
ajlm-1975	118	13	samples	sample	NOUN
ajlm-1975	118	14	with	with	ADP
ajlm-1975	118	15	discordant	discordant	ADJ
ajlm-1975	118	16	results	result	NOUN
ajlm-1975	118	17	(	(	PUNCT
ajlm-1975	118	18	i.e.	i.e.	X
ajlm-1975	118	19	52.7	52.7	NUM
ajlm-1975	118	20	%	%	NOUN
ajlm-1975	118	21	of	of	ADP
ajlm-1975	118	22	all	all	DET
ajlm-1975	118	23	discordant	discordant	ADJ
ajlm-1975	118	24	results	result	NOUN
ajlm-1975	118	25	are	be	AUX
ajlm-1975	118	26	due	due	ADJ
ajlm-1975	118	27	to	to	ADP
ajlm-1975	118	28	mutations	mutation	NOUN
ajlm-1975	118	29	outside	outside	ADP
ajlm-1975	118	30	the	the	DET
ajlm-1975	118	31	rrdr	rrdr	NOUN
ajlm-1975	118	32	)	)	PUNCT
ajlm-1975	118	33	,	,	PUNCT
ajlm-1975	118	34	this	this	PRON
ajlm-1975	118	35	will	will	AUX
ajlm-1975	118	36	equate	equate	VERB
ajlm-1975	118	37	to	to	ADP
ajlm-1975	118	38	76	76	NUM
ajlm-1975	118	39	out	out	ADP
ajlm-1975	118	40	of	of	ADP
ajlm-1975	118	41	145	145	NUM
ajlm-1975	118	42	discordant	discordant	ADJ
ajlm-1975	118	43	isolates	isolate	NOUN
ajlm-1975	118	44	.	.	PUNCT
ajlm-1975	119	1	this	this	PRON
ajlm-1975	119	2	means	mean	VERB
ajlm-1975	119	3	that	that	SCONJ
ajlm-1975	119	4	about	about	ADV
ajlm-1975	119	5	15	15	NUM
ajlm-1975	119	6	%	%	NOUN
ajlm-1975	119	7	(	(	PUNCT
ajlm-1975	119	8	76/505	76/505	NUM
ajlm-1975	119	9	)	)	PUNCT
ajlm-1975	119	10	of	of	ADP
ajlm-1975	119	11	isoniazid	isoniazid	NOUN
ajlm-1975	119	12	mono	mono	NOUN
ajlm-1975	119	13	-	-	PUNCT
ajlm-1975	119	14	resistant	resistant	ADJ
ajlm-1975	119	15	cases	case	NOUN
ajlm-1975	119	16	had	have	VERB
ajlm-1975	119	17	mutations	mutation	NOUN
ajlm-1975	119	18	outside	outside	ADP
ajlm-1975	119	19	the	the	DET
ajlm-1975	119	20	rrdr	rrdr	NOUN
ajlm-1975	119	21	.	.	PUNCT
ajlm-1975	120	1	this	this	PRON
ajlm-1975	120	2	is	be	AUX
ajlm-1975	120	3	the	the	DET
ajlm-1975	120	4	same	same	ADJ
ajlm-1975	120	5	prevalence	prevalence	NOUN
ajlm-1975	120	6	found	find	VERB
ajlm-1975	120	7	by	by	ADP
ajlm-1975	120	8	makhado	makhado	NOUN
ajlm-1975	120	9	et	et	PROPN
ajlm-1975	120	10	al	al	PROPN
ajlm-1975	120	11	.	.	PROPN
ajlm-1975	120	12	from	from	ADP
ajlm-1975	120	13	pretoria	pretoria	PROPN
ajlm-1975	120	14	,	,	PUNCT
ajlm-1975	120	15	south	south	PROPN
ajlm-1975	120	16	africa	africa	PROPN
ajlm-1975	120	17	,	,	PUNCT
ajlm-1975	120	18	when	when	SCONJ
ajlm-1975	120	19	they	they	PRON
ajlm-1975	120	20	screened	screen	VERB
ajlm-1975	120	21	isoniazid	isoniazid	NOUN
ajlm-1975	120	22	mono	mono	NOUN
ajlm-1975	120	23	-	-	PUNCT
ajlm-1975	120	24	resistant	resistant	ADJ
ajlm-1975	120	25	cases	case	NOUN
ajlm-1975	120	26	for	for	ADP
ajlm-1975	120	27	the	the	DET
ajlm-1975	120	28	i491f	i491f	PROPN
ajlm-1975	120	29	mutation	mutation	NOUN
ajlm-1975	120	30	in	in	ADP
ajlm-1975	120	31	clinical	clinical	ADJ
ajlm-1975	120	32	samples	sample	NOUN
ajlm-1975	120	33	collected	collect	VERB
ajlm-1975	120	34	between	between	ADP
ajlm-1975	120	35	2013	2013	NUM
ajlm-1975	120	36	and	and	CCONJ
ajlm-1975	120	37	2016.10	2016.10	NUM
ajlm-1975	120	38	unlike	unlike	ADP
ajlm-1975	120	39	makhado	makhado	INTJ
ajlm-1975	120	40	et	et	NOUN
ajlm-1975	120	41	al	al	PROPN
ajlm-1975	120	42	.	.	PROPN
ajlm-1975	120	43	,	,	PUNCT
ajlm-1975	120	44	who	who	PRON
ajlm-1975	120	45	used	use	VERB
ajlm-1975	120	46	molecular	molecular	ADJ
ajlm-1975	120	47	methods	method	NOUN
ajlm-1975	120	48	to	to	PART
ajlm-1975	120	49	screen	screen	VERB
ajlm-1975	120	50	for	for	ADP
ajlm-1975	120	51	the	the	DET
ajlm-1975	120	52	i491f	i491f	PROPN
ajlm-1975	120	53	mutation	mutation	NOUN
ajlm-1975	120	54	,	,	PUNCT
ajlm-1975	120	55	we	we	PRON
ajlm-1975	120	56	used	use	VERB
ajlm-1975	120	57	the	the	DET
ajlm-1975	120	58	1	1	NUM
ajlm-1975	120	59	%	%	NOUN
ajlm-1975	120	60	agar	agar	NOUN
ajlm-1975	120	61	proportion	proportion	NOUN
ajlm-1975	120	62	method	method	NOUN
ajlm-1975	120	63	to	to	PART
ajlm-1975	120	64	test	test	VERB
ajlm-1975	120	65	for	for	ADP
ajlm-1975	120	66	rifampicin	rifampicin	VERB
ajlm-1975	120	67	resistance	resistance	NOUN
ajlm-1975	120	68	missed	miss	VERB
ajlm-1975	120	69	by	by	ADP
ajlm-1975	120	70	the	the	DET
ajlm-1975	120	71	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	120	72	assay	assay	NOUN
ajlm-1975	120	73	.	.	PUNCT
ajlm-1975	121	1	phenotypic	phenotypic	ADJ
ajlm-1975	121	2	methods	method	NOUN
ajlm-1975	121	3	,	,	PUNCT
ajlm-1975	121	4	especially	especially	ADV
ajlm-1975	121	5	liquid	liquid	NOUN
ajlm-1975	121	6	-	-	PUNCT
ajlm-1975	121	7	based	base	VERB
ajlm-1975	121	8	methods	method	NOUN
ajlm-1975	121	9	,	,	PUNCT
ajlm-1975	121	10	can	can	AUX
ajlm-1975	121	11	fail	fail	VERB
ajlm-1975	121	12	to	to	PART
ajlm-1975	121	13	detect	detect	VERB
ajlm-1975	121	14	rifampicin	rifampicin	VERB
ajlm-1975	121	15	resistance	resistance	NOUN
ajlm-1975	121	16	caused	cause	VERB
ajlm-1975	121	17	by	by	ADP
ajlm-1975	121	18	the	the	DET
ajlm-1975	121	19	i491f	i491f	PROPN
ajlm-1975	121	20	mutation	mutation	NOUN
ajlm-1975	121	21	.	.	PUNCT
ajlm-1975	122	1	in	in	ADP
ajlm-1975	122	2	a	a	DET
ajlm-1975	122	3	2019	2019	NUM
ajlm-1975	122	4	study	study	NOUN
ajlm-1975	122	5	conducted	conduct	VERB
ajlm-1975	122	6	in	in	ADP
ajlm-1975	122	7	belgium	belgium	NOUN
ajlm-1975	122	8	by	by	ADP
ajlm-1975	122	9	torrea	torrea	NOUN
ajlm-1975	122	10	et	et	PROPN
ajlm-1975	122	11	al	al	PROPN
ajlm-1975	122	12	.	.	PROPN
ajlm-1975	122	13	,	,	PUNCT
ajlm-1975	122	14	the	the	DET
ajlm-1975	122	15	agar	agar	NOUN
ajlm-1975	122	16	proportion	proportion	NOUN
ajlm-1975	122	17	method	method	NOUN
ajlm-1975	122	18	detected	detect	VERB
ajlm-1975	122	19	rifampicin	rifampicin	VERB
ajlm-1975	122	20	resistance	resistance	NOUN
ajlm-1975	122	21	in	in	ADP
ajlm-1975	122	22	75	75	NUM
ajlm-1975	122	23	%	%	NOUN
ajlm-1975	122	24	of	of	ADP
ajlm-1975	122	25	isolates	isolate	NOUN
ajlm-1975	122	26	with	with	ADP
ajlm-1975	122	27	i491f	i491f	PROPN
ajlm-1975	122	28	that	that	PRON
ajlm-1975	122	29	was	be	AUX
ajlm-1975	122	30	missed	miss	VERB
ajlm-1975	122	31	by	by	ADP
ajlm-1975	122	32	the	the	DET
ajlm-1975	122	33	mycobacteria	mycobacteria	NOUN
ajlm-1975	122	34	growth	growth	NOUN
ajlm-1975	122	35	indicator	indicator	NOUN
ajlm-1975	122	36	tube	tube	NOUN
ajlm-1975	122	37	dst.12	dst.12	VERB
ajlm-1975	122	38	it	it	PRON
ajlm-1975	122	39	is	be	AUX
ajlm-1975	122	40	therefore	therefore	ADV
ajlm-1975	122	41	likely	likely	ADJ
ajlm-1975	122	42	that	that	SCONJ
ajlm-1975	122	43	the	the	DET
ajlm-1975	122	44	occurrence	occurrence	NOUN
ajlm-1975	122	45	of	of	ADP
ajlm-1975	122	46	these	these	DET
ajlm-1975	122	47	mutations	mutation	NOUN
ajlm-1975	122	48	is	be	AUX
ajlm-1975	122	49	more	more	ADV
ajlm-1975	122	50	frequent	frequent	ADJ
ajlm-1975	122	51	than	than	ADP
ajlm-1975	122	52	what	what	PRON
ajlm-1975	122	53	we	we	PRON
ajlm-1975	122	54	found	find	VERB
ajlm-1975	122	55	in	in	ADP
ajlm-1975	122	56	this	this	DET
ajlm-1975	122	57	study	study	NOUN
ajlm-1975	122	58	.	.	PUNCT
ajlm-1975	123	1	while	while	SCONJ
ajlm-1975	123	2	the	the	DET
ajlm-1975	123	3	overall	overall	ADJ
ajlm-1975	123	4	prevalence	prevalence	NOUN
ajlm-1975	123	5	of	of	ADP
ajlm-1975	123	6	i491f	i491f	PROPN
ajlm-1975	123	7	mutation	mutation	NOUN
ajlm-1975	123	8	among	among	ADP
ajlm-1975	123	9	tuberculosis	tuberculosis	NOUN
ajlm-1975	123	10	patients	patient	NOUN
ajlm-1975	123	11	is	be	AUX
ajlm-1975	123	12	reportedly	reportedly	ADV
ajlm-1975	123	13	low	low	ADJ
ajlm-1975	123	14	,	,	PUNCT
ajlm-1975	123	15	in	in	ADP
ajlm-1975	123	16	patients	patient	NOUN
ajlm-1975	123	17	with	with	ADP
ajlm-1975	123	18	isoniazid	isoniazid	NOUN
ajlm-1975	123	19	resistance	resistance	NOUN
ajlm-1975	123	20	,	,	PUNCT
ajlm-1975	123	21	the	the	DET
ajlm-1975	123	22	prevalence	prevalence	NOUN
ajlm-1975	123	23	is	be	AUX
ajlm-1975	123	24	high.9,10,20	high.9,10,20	ADJ
ajlm-1975	123	25	the	the	PRON
ajlm-1975	123	26	who	who	PRON
ajlm-1975	123	27	defines	define	VERB
ajlm-1975	123	28	universal	universal	ADJ
ajlm-1975	123	29	access	access	NOUN
ajlm-1975	123	30	to	to	ADP
ajlm-1975	123	31	dst	dst	NOUN
ajlm-1975	123	32	as	as	ADP
ajlm-1975	123	33	performing	perform	VERB
ajlm-1975	123	34	rapid	rapid	ADJ
ajlm-1975	123	35	dst	dst	NOUN
ajlm-1975	123	36	for	for	ADP
ajlm-1975	123	37	at	at	ADV
ajlm-1975	123	38	least	least	ADJ
ajlm-1975	123	39	rifampicin	rifampicin	VERB
ajlm-1975	123	40	in	in	ADP
ajlm-1975	123	41	all	all	DET
ajlm-1975	123	42	patients	patient	NOUN
ajlm-1975	123	43	with	with	ADP
ajlm-1975	123	44	bacteriologically	bacteriologically	ADV
ajlm-1975	123	45	confirmed	confirm	VERB
ajlm-1975	123	46	tuberculosis	tuberculosis	NOUN
ajlm-1975	123	47	plus	plus	CCONJ
ajlm-1975	123	48	additional	additional	ADJ
ajlm-1975	123	49	dst	dst	NOUN
ajlm-1975	123	50	for	for	ADP
ajlm-1975	123	51	at	at	ADP
ajlm-1975	123	52	least	least	ADJ
ajlm-1975	123	53	fluoroquinolones	fluoroquinolone	NOUN
ajlm-1975	123	54	and	and	CCONJ
ajlm-1975	123	55	second	second	ADJ
ajlm-1975	123	56	-	-	PUNCT
ajlm-1975	123	57	line	line	NOUN
ajlm-1975	123	58	injectable	injectable	ADJ
ajlm-1975	123	59	agents	agent	NOUN
ajlm-1975	123	60	in	in	ADP
ajlm-1975	123	61	patients	patient	NOUN
ajlm-1975	123	62	with	with	ADP
ajlm-1975	123	63	rifampicin	rifampicin	VERB
ajlm-1975	123	64	resistance.1	resistance.1	VERB
ajlm-1975	123	65	the	the	DET
ajlm-1975	123	66	use	use	NOUN
ajlm-1975	123	67	of	of	ADP
ajlm-1975	123	68	xpert	xpert	PROPN
ajlm-1975	123	69	as	as	ADP
ajlm-1975	123	70	an	an	DET
ajlm-1975	123	71	entry	entry	NOUN
ajlm-1975	123	72	point	point	NOUN
ajlm-1975	123	73	to	to	ADP
ajlm-1975	123	74	tuberculosis	tuberculosis	NOUN
ajlm-1975	123	75	care	care	NOUN
ajlm-1975	123	76	without	without	ADP
ajlm-1975	123	77	investigating	investigate	VERB
ajlm-1975	123	78	isoniazid	isoniazid	NOUN
ajlm-1975	123	79	resistance	resistance	NOUN
ajlm-1975	123	80	would	would	AUX
ajlm-1975	123	81	prove	prove	VERB
ajlm-1975	123	82	disastrous	disastrous	ADJ
ajlm-1975	123	83	for	for	ADP
ajlm-1975	123	84	patients	patient	NOUN
ajlm-1975	123	85	infected	infect	VERB
ajlm-1975	123	86	with	with	ADP
ajlm-1975	123	87	m.	m.	NOUN
ajlm-1975	123	88	tuberculosis	tuberculosis	NOUN
ajlm-1975	123	89	strains	strain	NOUN
ajlm-1975	123	90	that	that	PRON
ajlm-1975	123	91	have	have	VERB
ajlm-1975	123	92	mutations	mutation	NOUN
ajlm-1975	123	93	outside	outside	ADP
ajlm-1975	123	94	the	the	DET
ajlm-1975	123	95	area	area	NOUN
ajlm-1975	123	96	of	of	ADP
ajlm-1975	123	97	detection	detection	NOUN
ajlm-1975	123	98	and	and	CCONJ
ajlm-1975	123	99	are	be	AUX
ajlm-1975	123	100	resistant	resistant	ADJ
ajlm-1975	123	101	to	to	ADP
ajlm-1975	123	102	all	all	DET
ajlm-1975	123	103	other	other	ADJ
ajlm-1975	123	104	first	first	ADJ
ajlm-1975	123	105	-	-	PUNCT
ajlm-1975	123	106	line	line	NOUN
ajlm-1975	123	107	drugs	drug	NOUN
ajlm-1975	123	108	.	.	PUNCT
ajlm-1975	124	1	recent	recent	ADJ
ajlm-1975	124	2	studies	study	NOUN
ajlm-1975	124	3	conducted	conduct	VERB
ajlm-1975	124	4	between	between	ADP
ajlm-1975	124	5	2015	2015	NUM
ajlm-1975	124	6	and	and	CCONJ
ajlm-1975	124	7	2017	2017	NUM
ajlm-1975	124	8	have	have	AUX
ajlm-1975	124	9	shown	show	VERB
ajlm-1975	124	10	that	that	SCONJ
ajlm-1975	124	11	isoniazid	isoniazid	NOUN
ajlm-1975	124	12	resistance	resistance	NOUN
ajlm-1975	124	13	generally	generally	ADV
ajlm-1975	124	14	develops	develop	VERB
ajlm-1975	124	15	before	before	ADP
ajlm-1975	124	16	rifampicin	rifampicin	VERB
ajlm-1975	124	17	resistance.21,22	resistance.21,22	NOUN
ajlm-1975	124	18	notwithstanding	notwithstanding	ADP
ajlm-1975	124	19	the	the	DET
ajlm-1975	124	20	importance	importance	NOUN
ajlm-1975	124	21	of	of	ADP
ajlm-1975	124	22	testing	test	VERB
ajlm-1975	124	23	for	for	ADP
ajlm-1975	124	24	rifampicin	rifampicin	VERB
ajlm-1975	124	25	resistance	resistance	NOUN
ajlm-1975	124	26	,	,	PUNCT
ajlm-1975	124	27	the	the	DET
ajlm-1975	124	28	neglect	neglect	NOUN
ajlm-1975	124	29	of	of	ADP
ajlm-1975	124	30	isoniazid	isoniazid	NOUN
ajlm-1975	124	31	testing	testing	NOUN
ajlm-1975	124	32	leads	lead	VERB
ajlm-1975	124	33	to	to	ADP
ajlm-1975	124	34	inappropriate	inappropriate	ADJ
ajlm-1975	124	35	therapy	therapy	NOUN
ajlm-1975	124	36	,	,	PUNCT
ajlm-1975	124	37	treatment	treatment	NOUN
ajlm-1975	124	38	failure	failure	NOUN
ajlm-1975	124	39	and	and	CCONJ
ajlm-1975	124	40	accumulation	accumulation	NOUN
ajlm-1975	124	41	of	of	ADP
ajlm-1975	124	42	resistance	resistance	NOUN
ajlm-1975	124	43	in	in	ADP
ajlm-1975	124	44	patients	patient	NOUN
ajlm-1975	124	45	with	with	ADP
ajlm-1975	124	46	initial	initial	ADJ
ajlm-1975	124	47	isoniazid	isoniazid	NOUN
ajlm-1975	124	48	resistance.23	resistance.23	VERB
ajlm-1975	124	49	we	we	PRON
ajlm-1975	124	50	therefore	therefore	ADV
ajlm-1975	124	51	propose	propose	VERB
ajlm-1975	124	52	an	an	DET
ajlm-1975	124	53	algorithm	algorithm	NOUN
ajlm-1975	124	54	to	to	PART
ajlm-1975	124	55	optimise	optimise	VERB
ajlm-1975	124	56	dr	dr	PROPN
ajlm-1975	124	57	-	-	PUNCT
ajlm-1975	124	58	tb	tb	NOUN
ajlm-1975	124	59	detection	detection	NOUN
ajlm-1975	124	60	(	(	PUNCT
ajlm-1975	124	61	figure	figure	NOUN
ajlm-1975	124	62	2	2	NUM
ajlm-1975	124	63	)	)	PUNCT
ajlm-1975	124	64	.	.	PUNCT
ajlm-1975	125	1	we	we	PRON
ajlm-1975	125	2	submit	submit	VERB
ajlm-1975	125	3	that	that	SCONJ
ajlm-1975	125	4	the	the	DET
ajlm-1975	125	5	initial	initial	ADJ
ajlm-1975	125	6	dst	dst	NOUN
ajlm-1975	125	7	should	should	AUX
ajlm-1975	125	8	include	include	VERB
ajlm-1975	125	9	both	both	DET
ajlm-1975	125	10	isoniazid	isoniazid	NOUN
ajlm-1975	125	11	and	and	CCONJ
ajlm-1975	125	12	rifampicin	rifampicin	VERB
ajlm-1975	125	13	.	.	PUNCT
ajlm-1975	126	1	importantly	importantly	ADV
ajlm-1975	126	2	,	,	PUNCT
ajlm-1975	126	3	if	if	SCONJ
ajlm-1975	126	4	resistance	resistance	NOUN
ajlm-1975	126	5	is	be	AUX
ajlm-1975	126	6	found	find	VERB
ajlm-1975	126	7	to	to	ADP
ajlm-1975	126	8	any	any	PRON
ajlm-1975	126	9	of	of	ADP
ajlm-1975	126	10	these	these	DET
ajlm-1975	126	11	two	two	NUM
ajlm-1975	126	12	drugs	drug	NOUN
ajlm-1975	126	13	,	,	PUNCT
ajlm-1975	126	14	it	it	PRON
ajlm-1975	126	15	should	should	AUX
ajlm-1975	126	16	trigger	trigger	VERB
ajlm-1975	126	17	further	further	ADJ
ajlm-1975	126	18	dst	dst	NOUN
ajlm-1975	126	19	of	of	ADP
ajlm-1975	126	20	other	other	ADJ
ajlm-1975	126	21	first	first	ADJ
ajlm-1975	126	22	-	-	PUNCT
ajlm-1975	126	23	line	line	NOUN
ajlm-1975	126	24	and	and	CCONJ
ajlm-1975	126	25	second	second	ADJ
ajlm-1975	126	26	-	-	PUNCT
ajlm-1975	126	27	line	line	NOUN
ajlm-1975	126	28	drugs	drug	NOUN
ajlm-1975	126	29	that	that	PRON
ajlm-1975	126	30	will	will	AUX
ajlm-1975	126	31	be	be	AUX
ajlm-1975	126	32	used	use	VERB
ajlm-1975	126	33	for	for	ADP
ajlm-1975	126	34	treatment	treatment	NOUN
ajlm-1975	126	35	.	.	PUNCT
ajlm-1975	127	1	moreover	moreover	ADV
ajlm-1975	127	2	,	,	PUNCT
ajlm-1975	127	3	an	an	DET
ajlm-1975	127	4	attempt	attempt	NOUN
ajlm-1975	127	5	should	should	AUX
ajlm-1975	127	6	be	be	AUX
ajlm-1975	127	7	made	make	VERB
ajlm-1975	127	8	to	to	PART
ajlm-1975	127	9	look	look	VERB
ajlm-1975	127	10	for	for	ADP
ajlm-1975	127	11	the	the	DET
ajlm-1975	127	12	i491f	i491f	PROPN
ajlm-1975	127	13	mutation	mutation	NOUN
ajlm-1975	127	14	in	in	ADP
ajlm-1975	127	15	isolates	isolate	NOUN
ajlm-1975	127	16	from	from	ADP
ajlm-1975	127	17	patients	patient	NOUN
ajlm-1975	127	18	with	with	ADP
ajlm-1975	127	19	isoniazid	isoniazid	NOUN
ajlm-1975	127	20	mono	mono	NOUN
ajlm-1975	127	21	-	-	PUNCT
ajlm-1975	127	22	resistant	resistant	ADJ
ajlm-1975	127	23	tuberculosis	tuberculosis	NOUN
ajlm-1975	127	24	as	as	SCONJ
ajlm-1975	127	25	this	this	DET
ajlm-1975	127	26	mutation	mutation	NOUN
ajlm-1975	127	27	may	may	AUX
ajlm-1975	127	28	be	be	AUX
ajlm-1975	127	29	missed	miss	VERB
ajlm-1975	127	30	by	by	ADP
ajlm-1975	127	31	both	both	DET
ajlm-1975	127	32	phenotypic	phenotypic	ADJ
ajlm-1975	127	33	and	and	CCONJ
ajlm-1975	127	34	genotypic	genotypic	NOUN
ajlm-1975	127	35	dst	dst	NOUN
ajlm-1975	127	36	methods	method	NOUN
ajlm-1975	127	37	that	that	PRON
ajlm-1975	127	38	are	be	AUX
ajlm-1975	127	39	routinely	routinely	ADV
ajlm-1975	127	40	used	use	VERB
ajlm-1975	127	41	for	for	ADP
ajlm-1975	127	42	the	the	DET
ajlm-1975	127	43	detection	detection	NOUN
ajlm-1975	127	44	of	of	ADP
ajlm-1975	127	45	rifampicin	rifampicin	VERB
ajlm-1975	127	46	resistance	resistance	NOUN
ajlm-1975	127	47	.	.	PUNCT
ajlm-1975	128	1	figure	figure	NOUN
ajlm-1975	128	2	2	2	NUM
ajlm-1975	128	3	:	:	PUNCT
ajlm-1975	128	4	proposed	propose	VERB
ajlm-1975	128	5	algorithm	algorithm	NOUN
ajlm-1975	128	6	for	for	ADP
ajlm-1975	128	7	the	the	DET
ajlm-1975	128	8	diagnosis	diagnosis	NOUN
ajlm-1975	128	9	of	of	ADP
ajlm-1975	128	10	drug	drug	NOUN
ajlm-1975	128	11	-	-	PUNCT
ajlm-1975	128	12	resistant	resistant	ADJ
ajlm-1975	128	13	tuberculosis	tuberculosis	NOUN
ajlm-1975	128	14	.	.	PUNCT
ajlm-1975	129	1	the	the	DET
ajlm-1975	129	2	largest	large	ADJ
ajlm-1975	129	3	global	global	ADJ
ajlm-1975	129	4	cluster	cluster	NOUN
ajlm-1975	129	5	of	of	ADP
ajlm-1975	129	6	extensively	extensively	ADV
ajlm-1975	129	7	drug	drug	NOUN
ajlm-1975	129	8	-	-	PUNCT
ajlm-1975	129	9	resistant	resistant	ADJ
ajlm-1975	129	10	tuberculosis	tuberculosis	NOUN
ajlm-1975	129	11	that	that	PRON
ajlm-1975	129	12	was	be	AUX
ajlm-1975	129	13	ever	ever	ADV
ajlm-1975	129	14	reported	report	VERB
ajlm-1975	129	15	was	be	AUX
ajlm-1975	129	16	from	from	ADP
ajlm-1975	129	17	tugela	tugela	ADP
ajlm-1975	129	18	ferry	ferry	NOUN
ajlm-1975	129	19	in	in	ADP
ajlm-1975	129	20	kwazulu	kwazulu	NOUN
ajlm-1975	129	21	-	-	PUNCT
ajlm-1975	129	22	natal	natal	NOUN
ajlm-1975	129	23	in	in	ADP
ajlm-1975	129	24	2005	2005	NUM
ajlm-1975	129	25	and	and	CCONJ
ajlm-1975	129	26	it	it	PRON
ajlm-1975	129	27	was	be	AUX
ajlm-1975	129	28	caused	cause	VERB
ajlm-1975	129	29	by	by	ADP
ajlm-1975	129	30	a	a	DET
ajlm-1975	129	31	strain	strain	NOUN
ajlm-1975	129	32	named	name	VERB
ajlm-1975	129	33	f15	f15	PROPN
ajlm-1975	129	34	/	/	SYM
ajlm-1975	129	35	lam4	lam4	PROPN
ajlm-1975	129	36	/	/	SYM
ajlm-1975	129	37	kzn.24	kzn.24	NOUN
ajlm-1975	129	38	a	a	DET
ajlm-1975	129	39	study	study	NOUN
ajlm-1975	129	40	conducted	conduct	VERB
ajlm-1975	129	41	by	by	ADP
ajlm-1975	129	42	pillay	pillay	PROPN
ajlm-1975	129	43	et	et	PROPN
ajlm-1975	129	44	al	al	PROPN
ajlm-1975	129	45	.	.	PUNCT
ajlm-1975	130	1	using	use	VERB
ajlm-1975	130	2	m.	m.	NOUN
ajlm-1975	130	3	tuberculosis	tuberculosis	NOUN
ajlm-1975	130	4	isolates	isolate	NOUN
ajlm-1975	130	5	collected	collect	VERB
ajlm-1975	130	6	between	between	ADP
ajlm-1975	130	7	1994	1994	NUM
ajlm-1975	130	8	and	and	CCONJ
ajlm-1975	130	9	2002	2002	NUM
ajlm-1975	130	10	showed	show	VERB
ajlm-1975	130	11	how	how	SCONJ
ajlm-1975	130	12	this	this	DET
ajlm-1975	130	13	extensively	extensively	ADV
ajlm-1975	130	14	drug	drug	NOUN
ajlm-1975	130	15	-	-	PUNCT
ajlm-1975	130	16	resistant	resistant	ADJ
ajlm-1975	130	17	strain	strain	NOUN
ajlm-1975	130	18	accumulated	accumulate	VERB
ajlm-1975	130	19	resistance	resistance	NOUN
ajlm-1975	130	20	over	over	ADP
ajlm-1975	130	21	time	time	NOUN
ajlm-1975	130	22	under	under	ADP
ajlm-1975	130	23	a	a	DET
ajlm-1975	130	24	tuberculosis	tuberculosis	NOUN
ajlm-1975	130	25	programme	programme	NOUN
ajlm-1975	130	26	that	that	PRON
ajlm-1975	130	27	lacked	lack	VERB
ajlm-1975	130	28	appropriate	appropriate	ADJ
ajlm-1975	130	29	dst.25	dst.25	ADJ
ajlm-1975	130	30	patients	patient	NOUN
ajlm-1975	130	31	received	receive	VERB
ajlm-1975	130	32	inappropriate	inappropriate	ADJ
ajlm-1975	130	33	therapy	therapy	NOUN
ajlm-1975	130	34	,	,	PUNCT
ajlm-1975	130	35	thus	thus	ADV
ajlm-1975	130	36	allowing	allow	VERB
ajlm-1975	130	37	the	the	DET
ajlm-1975	130	38	selection	selection	NOUN
ajlm-1975	130	39	and	and	CCONJ
ajlm-1975	130	40	spread	spread	VERB
ajlm-1975	130	41	of	of	ADP
ajlm-1975	130	42	resistant	resistant	ADJ
ajlm-1975	130	43	strains	strain	NOUN
ajlm-1975	130	44	and	and	CCONJ
ajlm-1975	130	45	leading	lead	VERB
ajlm-1975	130	46	to	to	ADP
ajlm-1975	130	47	treatment	treatment	NOUN
ajlm-1975	130	48	failure	failure	NOUN
ajlm-1975	130	49	with	with	ADP
ajlm-1975	130	50	dire	dire	ADJ
ajlm-1975	130	51	consequences	consequence	NOUN
ajlm-1975	130	52	,	,	PUNCT
ajlm-1975	130	53	especially	especially	ADV
ajlm-1975	130	54	among	among	ADP
ajlm-1975	130	55	patients	patient	NOUN
ajlm-1975	130	56	who	who	PRON
ajlm-1975	130	57	were	be	AUX
ajlm-1975	130	58	also	also	ADV
ajlm-1975	130	59	hiv	hiv	PROPN
ajlm-1975	130	60	-	-	PUNCT
ajlm-1975	130	61	positive.24	positive.24	NOUN
ajlm-1975	130	62	with	with	ADP
ajlm-1975	130	63	the	the	DET
ajlm-1975	130	64	current	current	ADJ
ajlm-1975	130	65	tuberculosis	tuberculosis	PRON
ajlm-1975	130	66	diagnostic	diagnostic	ADJ
ajlm-1975	130	67	algorithm	algorithm	NOUN
ajlm-1975	130	68	that	that	PRON
ajlm-1975	130	69	only	only	ADV
ajlm-1975	130	70	tests	test	VERB
ajlm-1975	130	71	for	for	ADP
ajlm-1975	130	72	rifampicin	rifampicin	VERB
ajlm-1975	130	73	resistance	resistance	NOUN
ajlm-1975	130	74	,	,	PUNCT
ajlm-1975	130	75	we	we	PRON
ajlm-1975	130	76	find	find	VERB
ajlm-1975	130	77	ourselves	ourselves	PRON
ajlm-1975	130	78	in	in	ADP
ajlm-1975	130	79	a	a	DET
ajlm-1975	130	80	similar	similar	ADJ
ajlm-1975	130	81	circumstance	circumstance	NOUN
ajlm-1975	130	82	that	that	PRON
ajlm-1975	130	83	calls	call	VERB
ajlm-1975	130	84	for	for	ADP
ajlm-1975	130	85	swift	swift	ADJ
ajlm-1975	130	86	action	action	NOUN
ajlm-1975	130	87	if	if	SCONJ
ajlm-1975	130	88	we	we	PRON
ajlm-1975	130	89	are	be	AUX
ajlm-1975	130	90	to	to	PART
ajlm-1975	130	91	avoid	avoid	VERB
ajlm-1975	130	92	the	the	DET
ajlm-1975	130	93	same	same	ADJ
ajlm-1975	130	94	unfortunate	unfortunate	ADJ
ajlm-1975	130	95	outcome	outcome	NOUN
ajlm-1975	130	96	.	.	PUNCT
ajlm-1975	131	1	targeted	target	VERB
ajlm-1975	131	2	next	next	ADJ
ajlm-1975	131	3	-	-	PUNCT
ajlm-1975	131	4	generation	generation	NOUN
ajlm-1975	131	5	sequencing	sequencing	NOUN
ajlm-1975	131	6	can	can	AUX
ajlm-1975	131	7	overcome	overcome	VERB
ajlm-1975	131	8	some	some	PRON
ajlm-1975	131	9	of	of	ADP
ajlm-1975	131	10	the	the	DET
ajlm-1975	131	11	challenges	challenge	NOUN
ajlm-1975	131	12	of	of	ADP
ajlm-1975	131	13	rapid	rapid	ADJ
ajlm-1975	131	14	molecular	molecular	ADJ
ajlm-1975	131	15	assays	assay	NOUN
ajlm-1975	131	16	and	and	CCONJ
ajlm-1975	131	17	phenotypic	phenotypic	NOUN
ajlm-1975	131	18	dst	dst	NOUN
ajlm-1975	131	19	by	by	ADP
ajlm-1975	131	20	allowing	allow	VERB
ajlm-1975	131	21	the	the	DET
ajlm-1975	131	22	rapid	rapid	ADJ
ajlm-1975	131	23	detection	detection	NOUN
ajlm-1975	131	24	of	of	ADP
ajlm-1975	131	25	rpob	rpob	ADJ
ajlm-1975	131	26	mutations	mutation	NOUN
ajlm-1975	131	27	outside	outside	ADP
ajlm-1975	131	28	the	the	DET
ajlm-1975	131	29	rrdr	rrdr	NOUN
ajlm-1975	131	30	and	and	CCONJ
ajlm-1975	131	31	additional	additional	ADJ
ajlm-1975	131	32	mutations	mutation	NOUN
ajlm-1975	131	33	conferring	confer	VERB
ajlm-1975	131	34	resistance	resistance	NOUN
ajlm-1975	131	35	to	to	ADP
ajlm-1975	131	36	other	other	ADJ
ajlm-1975	131	37	anti	anti	ADJ
ajlm-1975	131	38	-	-	ADJ
ajlm-1975	131	39	tuberculosis	tuberculosis	ADJ
ajlm-1975	131	40	drugs	drug	NOUN
ajlm-1975	131	41	,	,	PUNCT
ajlm-1975	131	42	including	include	VERB
ajlm-1975	131	43	those	those	PRON
ajlm-1975	131	44	that	that	PRON
ajlm-1975	131	45	are	be	AUX
ajlm-1975	131	46	difficult	difficult	ADJ
ajlm-1975	131	47	to	to	PART
ajlm-1975	131	48	test	test	VERB
ajlm-1975	131	49	by	by	ADP
ajlm-1975	131	50	phenotypic	phenotypic	ADJ
ajlm-1975	131	51	methods	method	NOUN
ajlm-1975	131	52	(	(	PUNCT
ajlm-1975	131	53	e.g.	e.g.	ADV
ajlm-1975	131	54	pyrazinamide	pyrazinamide	NOUN
ajlm-1975	131	55	)	)	PUNCT
ajlm-1975	131	56	.	.	PUNCT
ajlm-1975	132	1	however	however	ADV
ajlm-1975	132	2	,	,	PUNCT
ajlm-1975	132	3	the	the	DET
ajlm-1975	132	4	cost	cost	NOUN
ajlm-1975	132	5	,	,	PUNCT
ajlm-1975	132	6	skill	skill	NOUN
ajlm-1975	132	7	levels	level	NOUN
ajlm-1975	132	8	and	and	CCONJ
ajlm-1975	132	9	expertise	expertise	NOUN
ajlm-1975	132	10	required	require	VERB
ajlm-1975	132	11	to	to	PART
ajlm-1975	132	12	perform	perform	VERB
ajlm-1975	132	13	next	next	ADJ
ajlm-1975	132	14	-	-	PUNCT
ajlm-1975	132	15	generation	generation	NOUN
ajlm-1975	132	16	sequencing	sequencing	NOUN
ajlm-1975	132	17	and	and	CCONJ
ajlm-1975	132	18	interpret	interpret	VERB
ajlm-1975	132	19	its	its	PRON
ajlm-1975	132	20	results	result	NOUN
ajlm-1975	132	21	remain	remain	VERB
ajlm-1975	132	22	the	the	DET
ajlm-1975	132	23	prohibiting	prohibit	VERB
ajlm-1975	132	24	factors	factor	NOUN
ajlm-1975	132	25	limiting	limit	VERB
ajlm-1975	132	26	the	the	DET
ajlm-1975	132	27	implementation	implementation	NOUN
ajlm-1975	132	28	of	of	ADP
ajlm-1975	132	29	this	this	DET
ajlm-1975	132	30	technology	technology	NOUN
ajlm-1975	132	31	,	,	PUNCT
ajlm-1975	132	32	especially	especially	ADV
ajlm-1975	132	33	in	in	ADP
ajlm-1975	132	34	high	high	ADV
ajlm-1975	132	35	-	-	PUNCT
ajlm-1975	132	36	burdened	burden	VERB
ajlm-1975	132	37	,	,	PUNCT
ajlm-1975	132	38	low	low	ADJ
ajlm-1975	132	39	-	-	PUNCT
ajlm-1975	132	40	resource	resource	NOUN
ajlm-1975	132	41	countries	country	NOUN
ajlm-1975	132	42	where	where	SCONJ
ajlm-1975	132	43	it	it	PRON
ajlm-1975	132	44	is	be	AUX
ajlm-1975	132	45	needed	need	VERB
ajlm-1975	132	46	the	the	DET
ajlm-1975	132	47	most.26	most.26	NOUN
ajlm-1975	132	48	therefore	therefore	ADV
ajlm-1975	132	49	,	,	PUNCT
ajlm-1975	132	50	in	in	ADP
ajlm-1975	132	51	many	many	ADJ
ajlm-1975	132	52	countries	country	NOUN
ajlm-1975	132	53	,	,	PUNCT
ajlm-1975	132	54	including	include	VERB
ajlm-1975	132	55	south	south	PROPN
ajlm-1975	132	56	africa	africa	PROPN
ajlm-1975	132	57	,	,	PUNCT
ajlm-1975	132	58	next	next	ADJ
ajlm-1975	132	59	-	-	PUNCT
ajlm-1975	132	60	generation	generation	NOUN
ajlm-1975	132	61	sequencing	sequence	VERB
ajlm-1975	132	62	remains	remain	NOUN
ajlm-1975	132	63	confined	confine	VERB
ajlm-1975	132	64	to	to	ADP
ajlm-1975	132	65	the	the	DET
ajlm-1975	132	66	reference	reference	NOUN
ajlm-1975	132	67	and	and	CCONJ
ajlm-1975	132	68	research	research	NOUN
ajlm-1975	132	69	laboratories	laboratory	NOUN
ajlm-1975	132	70	.	.	PUNCT
ajlm-1975	133	1	although	although	SCONJ
ajlm-1975	133	2	molecular	molecular	ADJ
ajlm-1975	133	3	tests	test	NOUN
ajlm-1975	133	4	have	have	AUX
ajlm-1975	133	5	decreased	decrease	VERB
ajlm-1975	133	6	the	the	DET
ajlm-1975	133	7	time	time	NOUN
ajlm-1975	133	8	to	to	ADP
ajlm-1975	133	9	tuberculosis	tuberculosis	NOUN
ajlm-1975	133	10	dst	dst	NOUN
ajlm-1975	133	11	results	result	NOUN
ajlm-1975	133	12	from	from	ADP
ajlm-1975	133	13	weeks	week	NOUN
ajlm-1975	133	14	,	,	PUNCT
ajlm-1975	133	15	using	use	VERB
ajlm-1975	133	16	the	the	DET
ajlm-1975	133	17	previous	previous	ADJ
ajlm-1975	133	18	phenotypic	phenotypic	ADJ
ajlm-1975	133	19	tests	test	NOUN
ajlm-1975	133	20	,	,	PUNCT
ajlm-1975	133	21	to	to	ADP
ajlm-1975	133	22	hours	hour	NOUN
ajlm-1975	133	23	and	and	CCONJ
ajlm-1975	133	24	days	day	NOUN
ajlm-1975	133	25	,	,	PUNCT
ajlm-1975	133	26	discordant	discordant	ADJ
ajlm-1975	133	27	results	result	NOUN
ajlm-1975	133	28	may	may	AUX
ajlm-1975	133	29	reverse	reverse	VERB
ajlm-1975	133	30	this	this	DET
ajlm-1975	133	31	benefit	benefit	NOUN
ajlm-1975	133	32	.	.	PUNCT
ajlm-1975	134	1	given	give	VERB
ajlm-1975	134	2	the	the	DET
ajlm-1975	134	3	fact	fact	NOUN
ajlm-1975	134	4	that	that	SCONJ
ajlm-1975	134	5	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	134	6	results	result	NOUN
ajlm-1975	134	7	in	in	ADP
ajlm-1975	134	8	this	this	DET
ajlm-1975	134	9	study	study	NOUN
ajlm-1975	134	10	showed	show	VERB
ajlm-1975	134	11	rifampicin	rifampicin	VERB
ajlm-1975	134	12	-	-	PUNCT
ajlm-1975	134	13	susceptible	susceptible	ADJ
ajlm-1975	134	14	m.	m.	NOUN
ajlm-1975	134	15	tuberculosis	tuberculosis	NOUN
ajlm-1975	134	16	,	,	PUNCT
ajlm-1975	134	17	appropriate	appropriate	ADJ
ajlm-1975	134	18	treatment	treatment	NOUN
ajlm-1975	134	19	(	(	PUNCT
ajlm-1975	134	20	dr	dr	NOUN
ajlm-1975	134	21	-	-	PUNCT
ajlm-1975	134	22	tb	tb	NOUN
ajlm-1975	134	23	treatment	treatment	NOUN
ajlm-1975	134	24	)	)	PUNCT
ajlm-1975	134	25	could	could	AUX
ajlm-1975	134	26	not	not	PART
ajlm-1975	134	27	be	be	AUX
ajlm-1975	134	28	initiated	initiate	VERB
ajlm-1975	134	29	until	until	SCONJ
ajlm-1975	134	30	phenotypic	phenotypic	ADJ
ajlm-1975	134	31	dst	dst	NOUN
ajlm-1975	134	32	results	result	NOUN
ajlm-1975	134	33	showing	show	VERB
ajlm-1975	134	34	rifampicin	rifampicin	VERB
ajlm-1975	134	35	resistance	resistance	NOUN
ajlm-1975	134	36	became	become	VERB
ajlm-1975	134	37	available	available	ADJ
ajlm-1975	134	38	.	.	PUNCT
ajlm-1975	135	1	even	even	ADV
ajlm-1975	135	2	so	so	ADV
ajlm-1975	135	3	,	,	PUNCT
ajlm-1975	135	4	due	due	ADP
ajlm-1975	135	5	to	to	ADP
ajlm-1975	135	6	the	the	DET
ajlm-1975	135	7	inferiority	inferiority	NOUN
ajlm-1975	135	8	of	of	ADP
ajlm-1975	135	9	second	second	ADJ
ajlm-1975	135	10	-	-	PUNCT
ajlm-1975	135	11	line	line	NOUN
ajlm-1975	135	12	tuberculosis	tuberculosis	NOUN
ajlm-1975	135	13	treatment	treatment	NOUN
ajlm-1975	135	14	compared	compare	VERB
ajlm-1975	135	15	to	to	ADP
ajlm-1975	135	16	the	the	DET
ajlm-1975	135	17	standard	standard	ADJ
ajlm-1975	135	18	first	first	ADJ
ajlm-1975	135	19	-	-	PUNCT
ajlm-1975	135	20	line	line	NOUN
ajlm-1975	135	21	treatment	treatment	NOUN
ajlm-1975	135	22	,	,	PUNCT
ajlm-1975	135	23	clinicians	clinician	NOUN
ajlm-1975	135	24	may	may	AUX
ajlm-1975	135	25	be	be	AUX
ajlm-1975	135	26	reluctant	reluctant	ADJ
ajlm-1975	135	27	to	to	PART
ajlm-1975	135	28	change	change	VERB
ajlm-1975	135	29	patient	patient	ADJ
ajlm-1975	135	30	treatment	treatment	NOUN
ajlm-1975	135	31	based	base	VERB
ajlm-1975	135	32	on	on	ADP
ajlm-1975	135	33	a	a	DET
ajlm-1975	135	34	discordant	discordant	ADJ
ajlm-1975	135	35	result	result	NOUN
ajlm-1975	135	36	.	.	PUNCT
ajlm-1975	136	1	the	the	DET
ajlm-1975	136	2	patients	patient	NOUN
ajlm-1975	136	3	in	in	ADP
ajlm-1975	136	4	this	this	DET
ajlm-1975	136	5	study	study	NOUN
ajlm-1975	136	6	often	often	ADV
ajlm-1975	136	7	had	have	VERB
ajlm-1975	136	8	multiple	multiple	ADJ
ajlm-1975	136	9	results	result	NOUN
ajlm-1975	136	10	,	,	PUNCT
ajlm-1975	136	11	showing	show	VERB
ajlm-1975	136	12	that	that	SCONJ
ajlm-1975	136	13	the	the	DET
ajlm-1975	136	14	clinicians	clinician	NOUN
ajlm-1975	136	15	sought	seek	VERB
ajlm-1975	136	16	more	more	ADJ
ajlm-1975	136	17	evidence	evidence	NOUN
ajlm-1975	136	18	before	before	ADP
ajlm-1975	136	19	committing	commit	VERB
ajlm-1975	136	20	patients	patient	NOUN
ajlm-1975	136	21	to	to	ADP
ajlm-1975	136	22	dr	dr	PROPN
ajlm-1975	136	23	-	-	PUNCT
ajlm-1975	136	24	tb	tb	NOUN
ajlm-1975	136	25	treatment	treatment	NOUN
ajlm-1975	136	26	regimens	regimen	NOUN
ajlm-1975	136	27	.	.	PUNCT
ajlm-1975	137	1	as	as	SCONJ
ajlm-1975	137	2	shown	show	VERB
ajlm-1975	137	3	in	in	ADP
ajlm-1975	137	4	this	this	DET
ajlm-1975	137	5	study	study	NOUN
ajlm-1975	137	6	,	,	PUNCT
ajlm-1975	137	7	there	there	PRON
ajlm-1975	137	8	were	be	VERB
ajlm-1975	137	9	significant	significant	ADJ
ajlm-1975	137	10	delays	delay	NOUN
ajlm-1975	137	11	in	in	ADP
ajlm-1975	137	12	the	the	DET
ajlm-1975	137	13	initiation	initiation	NOUN
ajlm-1975	137	14	of	of	ADP
ajlm-1975	137	15	dr	dr	PROPN
ajlm-1975	137	16	-	-	PUNCT
ajlm-1975	137	17	tb	tb	NOUN
ajlm-1975	137	18	treatment	treatment	NOUN
ajlm-1975	137	19	,	,	PUNCT
ajlm-1975	137	20	which	which	PRON
ajlm-1975	137	21	devalues	devalue	VERB
ajlm-1975	137	22	the	the	DET
ajlm-1975	137	23	benefits	benefit	NOUN
ajlm-1975	137	24	of	of	ADP
ajlm-1975	137	25	rapid	rapid	ADJ
ajlm-1975	137	26	molecular	molecular	ADJ
ajlm-1975	137	27	tests	test	NOUN
ajlm-1975	137	28	.	.	PUNCT
ajlm-1975	138	1	it	it	PRON
ajlm-1975	138	2	was	be	AUX
ajlm-1975	138	3	alarming	alarming	ADJ
ajlm-1975	138	4	to	to	PART
ajlm-1975	138	5	find	find	VERB
ajlm-1975	138	6	such	such	ADJ
ajlm-1975	138	7	high	high	ADJ
ajlm-1975	138	8	levels	level	NOUN
ajlm-1975	138	9	of	of	ADP
ajlm-1975	138	10	resistance	resistance	NOUN
ajlm-1975	138	11	to	to	ADP
ajlm-1975	138	12	other	other	ADJ
ajlm-1975	138	13	first	first	ADJ
ajlm-1975	138	14	-	-	PUNCT
ajlm-1975	138	15	line	line	NOUN
ajlm-1975	138	16	drugs	drug	NOUN
ajlm-1975	138	17	(	(	PUNCT
ajlm-1975	138	18	pyrazinamide	pyrazinamide	NOUN
ajlm-1975	138	19	and	and	CCONJ
ajlm-1975	138	20	ethambutol	ethambutol	ADJ
ajlm-1975	138	21	)	)	PUNCT
ajlm-1975	138	22	,	,	PUNCT
ajlm-1975	138	23	as	as	ADV
ajlm-1975	138	24	well	well	ADV
ajlm-1975	138	25	as	as	ADP
ajlm-1975	138	26	ethionamide	ethionamide	NOUN
ajlm-1975	138	27	and	and	CCONJ
ajlm-1975	138	28	streptomycin	streptomycin	PROPN
ajlm-1975	138	29	.	.	PUNCT
ajlm-1975	139	1	phenotypic	phenotypic	PROPN
ajlm-1975	139	2	dst	dst	PROPN
ajlm-1975	139	3	for	for	ADP
ajlm-1975	139	4	pyrazinamide	pyrazinamide	NOUN
ajlm-1975	139	5	and	and	CCONJ
ajlm-1975	139	6	ethambutol	ethambutol	NOUN
ajlm-1975	139	7	is	be	AUX
ajlm-1975	139	8	not	not	PART
ajlm-1975	139	9	routinely	routinely	ADV
ajlm-1975	139	10	performed	perform	VERB
ajlm-1975	139	11	in	in	ADP
ajlm-1975	139	12	many	many	ADJ
ajlm-1975	139	13	settings	setting	NOUN
ajlm-1975	139	14	because	because	SCONJ
ajlm-1975	139	15	of	of	ADP
ajlm-1975	139	16	poor	poor	ADJ
ajlm-1975	139	17	reproducibility	reproducibility	NOUN
ajlm-1975	139	18	and	and	CCONJ
ajlm-1975	139	19	reliability.27,28,29	reliability.27,28,29	PROPN
ajlm-1975	139	20	in	in	ADP
ajlm-1975	139	21	the	the	DET
ajlm-1975	139	22	south	south	ADJ
ajlm-1975	139	23	african	african	ADJ
ajlm-1975	139	24	setting	set	VERB
ajlm-1975	139	25	where	where	SCONJ
ajlm-1975	139	26	xpert	xpert	PROPN
ajlm-1975	139	27	(	(	PUNCT
ajlm-1975	139	28	ultra	ultra	ADJ
ajlm-1975	139	29	)	)	PUNCT
ajlm-1975	139	30	is	be	AUX
ajlm-1975	139	31	used	use	VERB
ajlm-1975	139	32	for	for	ADP
ajlm-1975	139	33	the	the	DET
ajlm-1975	139	34	initial	initial	ADJ
ajlm-1975	139	35	diagnosis	diagnosis	NOUN
ajlm-1975	139	36	of	of	ADP
ajlm-1975	139	37	tuberculosis	tuberculosis	NOUN
ajlm-1975	139	38	and	and	CCONJ
ajlm-1975	139	39	no	no	PRON
ajlm-1975	139	40	further	further	ADJ
ajlm-1975	139	41	dst	dst	NOUN
ajlm-1975	139	42	is	be	AUX
ajlm-1975	139	43	performed	perform	VERB
ajlm-1975	139	44	for	for	ADP
ajlm-1975	139	45	rifampicin	rifampicin	VERB
ajlm-1975	139	46	-	-	PUNCT
ajlm-1975	139	47	susceptible	susceptible	ADJ
ajlm-1975	139	48	cases	case	NOUN
ajlm-1975	139	49	,	,	PUNCT
ajlm-1975	139	50	these	these	DET
ajlm-1975	139	51	patients	patient	NOUN
ajlm-1975	139	52	would	would	AUX
ajlm-1975	139	53	be	be	AUX
ajlm-1975	139	54	treated	treat	VERB
ajlm-1975	139	55	with	with	ADP
ajlm-1975	139	56	first	first	ADJ
ajlm-1975	139	57	-	-	PUNCT
ajlm-1975	139	58	line	line	NOUN
ajlm-1975	139	59	therapy	therapy	NOUN
ajlm-1975	139	60	.	.	PUNCT
ajlm-1975	140	1	in	in	ADP
ajlm-1975	140	2	fact	fact	NOUN
ajlm-1975	140	3	,	,	PUNCT
ajlm-1975	140	4	given	give	VERB
ajlm-1975	140	5	the	the	DET
ajlm-1975	140	6	high	high	ADJ
ajlm-1975	140	7	number	number	NOUN
ajlm-1975	140	8	of	of	ADP
ajlm-1975	140	9	patients	patient	NOUN
ajlm-1975	140	10	with	with	ADP
ajlm-1975	140	11	a	a	DET
ajlm-1975	140	12	previous	previous	ADJ
ajlm-1975	140	13	tuberculosis	tuberculosis	NOUN
ajlm-1975	140	14	treatment	treatment	NOUN
ajlm-1975	140	15	history	history	NOUN
ajlm-1975	140	16	and	and	CCONJ
ajlm-1975	140	17	current	current	ADJ
ajlm-1975	140	18	indications	indication	NOUN
ajlm-1975	140	19	for	for	ADP
ajlm-1975	140	20	performing	perform	VERB
ajlm-1975	140	21	m.	m.	NOUN
ajlm-1975	140	22	tuberculosis	tuberculosis	NOUN
ajlm-1975	140	23	culture	culture	NOUN
ajlm-1975	140	24	,	,	PUNCT
ajlm-1975	140	25	phenotypic	phenotypic	ADJ
ajlm-1975	140	26	dst	dst	NOUN
ajlm-1975	140	27	was	be	AUX
ajlm-1975	140	28	probably	probably	ADV
ajlm-1975	140	29	performed	perform	VERB
ajlm-1975	140	30	for	for	ADP
ajlm-1975	140	31	these	these	DET
ajlm-1975	140	32	patients	patient	NOUN
ajlm-1975	140	33	because	because	SCONJ
ajlm-1975	140	34	they	they	PRON
ajlm-1975	140	35	had	have	AUX
ajlm-1975	140	36	already	already	ADV
ajlm-1975	140	37	failed	fail	VERB
ajlm-1975	140	38	tuberculosis	tuberculosis	NOUN
ajlm-1975	140	39	therapy	therapy	NOUN
ajlm-1975	140	40	.	.	PUNCT
ajlm-1975	141	1	the	the	DET
ajlm-1975	141	2	presence	presence	NOUN
ajlm-1975	141	3	of	of	ADP
ajlm-1975	141	4	resistance	resistance	NOUN
ajlm-1975	141	5	to	to	ADP
ajlm-1975	141	6	streptomycin	streptomycin	PROPN
ajlm-1975	141	7	suggests	suggest	VERB
ajlm-1975	141	8	that	that	SCONJ
ajlm-1975	141	9	these	these	DET
ajlm-1975	141	10	patients	patient	NOUN
ajlm-1975	141	11	may	may	AUX
ajlm-1975	141	12	have	have	AUX
ajlm-1975	141	13	failed	fail	VERB
ajlm-1975	141	14	a	a	DET
ajlm-1975	141	15	few	few	ADJ
ajlm-1975	141	16	rounds	round	NOUN
ajlm-1975	141	17	of	of	ADP
ajlm-1975	141	18	tuberculosis	tuberculosis	NOUN
ajlm-1975	141	19	therapy	therapy	NOUN
ajlm-1975	141	20	because	because	SCONJ
ajlm-1975	141	21	streptomycin	streptomycin	PROPN
ajlm-1975	141	22	was	be	AUX
ajlm-1975	141	23	previously	previously	ADV
ajlm-1975	141	24	used	use	VERB
ajlm-1975	141	25	as	as	ADP
ajlm-1975	141	26	part	part	NOUN
ajlm-1975	141	27	of	of	ADP
ajlm-1975	141	28	a	a	DET
ajlm-1975	141	29	standard	standard	ADJ
ajlm-1975	141	30	re	re	ADJ
ajlm-1975	141	31	-	-	NOUN
ajlm-1975	141	32	treatment	treatment	NOUN
ajlm-1975	141	33	regimen	regiman	NOUN
ajlm-1975	141	34	in	in	ADP
ajlm-1975	141	35	patients	patient	NOUN
ajlm-1975	141	36	who	who	PRON
ajlm-1975	141	37	had	have	AUX
ajlm-1975	141	38	failed	fail	VERB
ajlm-1975	141	39	first	first	ADJ
ajlm-1975	141	40	-	-	PUNCT
ajlm-1975	141	41	line	line	NOUN
ajlm-1975	141	42	therapy	therapy	NOUN
ajlm-1975	141	43	.	.	PUNCT
ajlm-1975	142	1	in	in	ADP
ajlm-1975	142	2	south	south	PROPN
ajlm-1975	142	3	africa	africa	PROPN
ajlm-1975	142	4	,	,	PUNCT
ajlm-1975	142	5	this	this	DET
ajlm-1975	142	6	regimen	regimen	NOUN
ajlm-1975	142	7	was	be	AUX
ajlm-1975	142	8	stopped	stop	VERB
ajlm-1975	142	9	after	after	ADP
ajlm-1975	142	10	the	the	DET
ajlm-1975	142	11	rollout	rollout	PROPN
ajlm-1975	142	12	of	of	ADP
ajlm-1975	142	13	xpert	xpert	PROPN
ajlm-1975	142	14	,	,	PUNCT
ajlm-1975	142	15	which	which	PRON
ajlm-1975	142	16	allowed	allow	VERB
ajlm-1975	142	17	universal	universal	ADJ
ajlm-1975	142	18	testing	testing	NOUN
ajlm-1975	142	19	of	of	ADP
ajlm-1975	142	20	all	all	DET
ajlm-1975	142	21	tuberculosis	tuberculosis	NOUN
ajlm-1975	142	22	patients	patient	NOUN
ajlm-1975	142	23	.	.	PUNCT
ajlm-1975	143	1	the	the	DET
ajlm-1975	143	2	rollout	rollout	PROPN
ajlm-1975	143	3	of	of	ADP
ajlm-1975	143	4	xpert	xpert	PROPN
ajlm-1975	143	5	was	be	AUX
ajlm-1975	143	6	completed	complete	VERB
ajlm-1975	143	7	towards	towards	ADP
ajlm-1975	143	8	the	the	DET
ajlm-1975	143	9	end	end	NOUN
ajlm-1975	143	10	of	of	ADP
ajlm-1975	143	11	2013	2013	NUM
ajlm-1975	143	12	.	.	PUNCT
ajlm-1975	144	1	isolates	isolate	NOUN
ajlm-1975	144	2	in	in	ADP
ajlm-1975	144	3	this	this	DET
ajlm-1975	144	4	study	study	NOUN
ajlm-1975	144	5	belonged	belong	VERB
ajlm-1975	144	6	predominantly	predominantly	ADV
ajlm-1975	144	7	to	to	PART
ajlm-1975	144	8	lineage	lineage	VERB
ajlm-1975	144	9	4	4	NUM
ajlm-1975	144	10	,	,	PUNCT
ajlm-1975	144	11	which	which	PRON
ajlm-1975	144	12	is	be	AUX
ajlm-1975	144	13	known	know	VERB
ajlm-1975	144	14	to	to	PART
ajlm-1975	144	15	predominate	predominate	VERB
ajlm-1975	144	16	among	among	ADP
ajlm-1975	144	17	dr	dr	PROPN
ajlm-1975	144	18	-	-	PUNCT
ajlm-1975	144	19	tb	tb	NOUN
ajlm-1975	144	20	cases	case	NOUN
ajlm-1975	144	21	in	in	ADP
ajlm-1975	144	22	the	the	DET
ajlm-1975	144	23	kwazulu	kwazulu	NOUN
ajlm-1975	144	24	-	-	PUNCT
ajlm-1975	144	25	natal	natal	ADJ
ajlm-1975	144	26	province.30	province.30	NOUN
ajlm-1975	144	27	most	most	ADJ
ajlm-1975	144	28	of	of	ADP
ajlm-1975	144	29	the	the	DET
ajlm-1975	144	30	isolates	isolate	NOUN
ajlm-1975	144	31	clustered	cluster	VERB
ajlm-1975	144	32	based	base	VERB
ajlm-1975	144	33	on	on	ADP
ajlm-1975	144	34	the	the	DET
ajlm-1975	144	35	i491f	i491f	PROPN
ajlm-1975	144	36	and	and	CCONJ
ajlm-1975	144	37	l452p	l452p	PROPN
ajlm-1975	144	38	rpob	rpob	PROPN
ajlm-1975	144	39	mutations	mutation	NOUN
ajlm-1975	144	40	,	,	PUNCT
ajlm-1975	144	41	with	with	ADP
ajlm-1975	144	42	each	each	DET
ajlm-1975	144	43	cluster	cluster	NOUN
ajlm-1975	144	44	carrying	carry	VERB
ajlm-1975	144	45	a	a	DET
ajlm-1975	144	46	unique	unique	ADJ
ajlm-1975	144	47	set	set	NOUN
ajlm-1975	144	48	of	of	ADP
ajlm-1975	144	49	mutations	mutation	NOUN
ajlm-1975	144	50	conferring	confer	VERB
ajlm-1975	144	51	resistance	resistance	NOUN
ajlm-1975	144	52	against	against	ADP
ajlm-1975	144	53	isoniazid	isoniazid	NOUN
ajlm-1975	144	54	,	,	PUNCT
ajlm-1975	144	55	pyrazinamide	pyrazinamide	PROPN
ajlm-1975	144	56	,	,	PUNCT
ajlm-1975	144	57	ethambutol	ethambutol	ADJ
ajlm-1975	144	58	,	,	PUNCT
ajlm-1975	144	59	streptomycin	streptomycin	PROPN
ajlm-1975	144	60	,	,	PUNCT
ajlm-1975	144	61	or	or	CCONJ
ajlm-1975	144	62	ethionamide	ethionamide	NOUN
ajlm-1975	144	63	.	.	PUNCT
ajlm-1975	145	1	this	this	PRON
ajlm-1975	145	2	suggests	suggest	VERB
ajlm-1975	145	3	that	that	SCONJ
ajlm-1975	145	4	these	these	DET
ajlm-1975	145	5	highly	highly	ADV
ajlm-1975	145	6	resistant	resistant	ADJ
ajlm-1975	145	7	strains	strain	NOUN
ajlm-1975	145	8	may	may	AUX
ajlm-1975	145	9	have	have	AUX
ajlm-1975	145	10	been	be	AUX
ajlm-1975	145	11	spreading	spread	VERB
ajlm-1975	145	12	undetected	undetected	ADJ
ajlm-1975	145	13	in	in	ADP
ajlm-1975	145	14	the	the	DET
ajlm-1975	145	15	community	community	NOUN
ajlm-1975	145	16	.	.	PUNCT
ajlm-1975	146	1	furthermore	furthermore	ADV
ajlm-1975	146	2	,	,	PUNCT
ajlm-1975	146	3	lineage	lineage	NOUN
ajlm-1975	146	4	4.4.1.1	4.4.1.1	NUM
ajlm-1975	146	5	strains	strain	NOUN
ajlm-1975	146	6	with	with	ADP
ajlm-1975	146	7	rpob	rpob	PROPN
ajlm-1975	146	8	i491f	i491f	PROPN
ajlm-1975	146	9	,	,	PUNCT
ajlm-1975	146	10	katg	katg	PROPN
ajlm-1975	146	11	s315	s315	PROPN
ajlm-1975	146	12	t	t	PROPN
ajlm-1975	146	13	,	,	PUNCT
ajlm-1975	146	14	pnca	pnca	PROPN
ajlm-1975	146	15	h51d	h51d	PROPN
ajlm-1975	146	16	,	,	PUNCT
ajlm-1975	146	17	embb	embb	ADJ
ajlm-1975	146	18	m306i	m306i	PROPN
ajlm-1975	146	19	,	,	PUNCT
ajlm-1975	146	20	and	and	CCONJ
ajlm-1975	146	21	rpsl	rpsl	VERB
ajlm-1975	146	22	k43r	k43r	PRON
ajlm-1975	146	23	mutations	mutation	NOUN
ajlm-1975	146	24	have	have	AUX
ajlm-1975	146	25	been	be	AUX
ajlm-1975	146	26	linked	link	VERB
ajlm-1975	146	27	to	to	ADP
ajlm-1975	146	28	an	an	DET
ajlm-1975	146	29	outbreak	outbreak	NOUN
ajlm-1975	146	30	that	that	PRON
ajlm-1975	146	31	originated	originate	VERB
ajlm-1975	146	32	in	in	ADP
ajlm-1975	146	33	eswatini	eswatini	NOUN
ajlm-1975	146	34	and	and	CCONJ
ajlm-1975	146	35	later	later	ADV
ajlm-1975	146	36	spread	spread	VERB
ajlm-1975	146	37	to	to	ADP
ajlm-1975	146	38	south	south	ADJ
ajlm-1975	146	39	africa.10	africa.10	ADJ
ajlm-1975	146	40	limitations	limitation	NOUN
ajlm-1975	146	41	this	this	DET
ajlm-1975	146	42	study	study	NOUN
ajlm-1975	146	43	reports	report	VERB
ajlm-1975	146	44	old	old	ADJ
ajlm-1975	146	45	data	datum	NOUN
ajlm-1975	146	46	on	on	ADP
ajlm-1975	146	47	m.	m.	NOUN
ajlm-1975	146	48	tuberculosis	tuberculosis	NOUN
ajlm-1975	146	49	isolates	isolate	NOUN
ajlm-1975	146	50	from	from	ADP
ajlm-1975	146	51	2014	2014	NUM
ajlm-1975	146	52	.	.	PUNCT
ajlm-1975	147	1	however	however	ADV
ajlm-1975	147	2	,	,	PUNCT
ajlm-1975	147	3	we	we	PRON
ajlm-1975	147	4	examined	examine	VERB
ajlm-1975	147	5	this	this	DET
ajlm-1975	147	6	period	period	NOUN
ajlm-1975	147	7	because	because	SCONJ
ajlm-1975	147	8	this	this	PRON
ajlm-1975	147	9	was	be	AUX
ajlm-1975	147	10	when	when	SCONJ
ajlm-1975	147	11	both	both	PRON
ajlm-1975	147	12	phenotypic	phenotypic	ADJ
ajlm-1975	147	13	and	and	CCONJ
ajlm-1975	147	14	genotypic	genotypic	NOUN
ajlm-1975	147	15	rifampicin	rifampicin	VERB
ajlm-1975	147	16	dst	dst	NOUN
ajlm-1975	147	17	were	be	AUX
ajlm-1975	147	18	performed	perform	VERB
ajlm-1975	147	19	simultaneously	simultaneously	ADV
ajlm-1975	147	20	in	in	ADP
ajlm-1975	147	21	our	our	PRON
ajlm-1975	147	22	setting	setting	NOUN
ajlm-1975	147	23	.	.	PUNCT
ajlm-1975	148	1	moreover	moreover	ADV
ajlm-1975	148	2	,	,	PUNCT
ajlm-1975	148	3	the	the	DET
ajlm-1975	148	4	tuberculosis	tuberculosis	NOUN
ajlm-1975	148	5	diagnostic	diagnostic	ADJ
ajlm-1975	148	6	algorithm	algorithm	NOUN
ajlm-1975	148	7	has	have	AUX
ajlm-1975	148	8	not	not	PART
ajlm-1975	148	9	changed	change	VERB
ajlm-1975	148	10	since	since	SCONJ
ajlm-1975	148	11	then	then	ADV
ajlm-1975	148	12	,	,	PUNCT
ajlm-1975	148	13	although	although	SCONJ
ajlm-1975	148	14	phenotypic	phenotypic	ADJ
ajlm-1975	148	15	rifampicin	rifampicin	VERB
ajlm-1975	148	16	dst	dst	NOUN
ajlm-1975	148	17	was	be	AUX
ajlm-1975	148	18	subsequently	subsequently	ADV
ajlm-1975	148	19	stopped	stop	VERB
ajlm-1975	148	20	.	.	PUNCT
ajlm-1975	149	1	another	another	DET
ajlm-1975	149	2	limitation	limitation	NOUN
ajlm-1975	149	3	of	of	ADP
ajlm-1975	149	4	this	this	DET
ajlm-1975	149	5	study	study	NOUN
ajlm-1975	149	6	was	be	AUX
ajlm-1975	149	7	our	our	PRON
ajlm-1975	149	8	use	use	NOUN
ajlm-1975	149	9	of	of	ADP
ajlm-1975	149	10	phenotypic	phenotypic	ADJ
ajlm-1975	149	11	dst	dst	NOUN
ajlm-1975	149	12	to	to	PART
ajlm-1975	149	13	select	select	VERB
ajlm-1975	149	14	isolates	isolate	NOUN
ajlm-1975	149	15	with	with	ADP
ajlm-1975	149	16	possible	possible	ADJ
ajlm-1975	149	17	mutations	mutation	NOUN
ajlm-1975	149	18	outside	outside	ADP
ajlm-1975	149	19	the	the	DET
ajlm-1975	149	20	rrdr	rrdr	NOUN
ajlm-1975	149	21	instead	instead	ADV
ajlm-1975	149	22	of	of	ADP
ajlm-1975	149	23	using	use	VERB
ajlm-1975	149	24	molecular	molecular	ADJ
ajlm-1975	149	25	screening	screening	NOUN
ajlm-1975	149	26	.	.	PUNCT
ajlm-1975	150	1	this	this	PRON
ajlm-1975	150	2	may	may	AUX
ajlm-1975	150	3	have	have	AUX
ajlm-1975	150	4	underestimated	underestimate	VERB
ajlm-1975	150	5	the	the	DET
ajlm-1975	150	6	prevalence	prevalence	NOUN
ajlm-1975	150	7	of	of	ADP
ajlm-1975	150	8	isolates	isolate	NOUN
ajlm-1975	150	9	with	with	ADP
ajlm-1975	150	10	these	these	DET
ajlm-1975	150	11	mutations	mutation	NOUN
ajlm-1975	150	12	as	as	SCONJ
ajlm-1975	150	13	some	some	PRON
ajlm-1975	150	14	of	of	ADP
ajlm-1975	150	15	them	they	PRON
ajlm-1975	150	16	remain	remain	VERB
ajlm-1975	150	17	susceptible	susceptible	ADJ
ajlm-1975	150	18	on	on	ADP
ajlm-1975	150	19	the	the	DET
ajlm-1975	150	20	phenotypic	phenotypic	NOUN
ajlm-1975	150	21	assay	assay	NOUN
ajlm-1975	150	22	.	.	PUNCT
ajlm-1975	151	1	due	due	ADP
ajlm-1975	151	2	to	to	ADP
ajlm-1975	151	3	limited	limited	ADJ
ajlm-1975	151	4	resources	resource	NOUN
ajlm-1975	151	5	,	,	PUNCT
ajlm-1975	151	6	we	we	PRON
ajlm-1975	151	7	sequenced	sequence	VERB
ajlm-1975	151	8	only	only	ADV
ajlm-1975	151	9	a	a	DET
ajlm-1975	151	10	subset	subset	NOUN
ajlm-1975	151	11	of	of	ADP
ajlm-1975	151	12	the	the	DET
ajlm-1975	151	13	isolates	isolate	NOUN
ajlm-1975	151	14	with	with	ADP
ajlm-1975	151	15	discordant	discordant	ADJ
ajlm-1975	151	16	results	result	NOUN
ajlm-1975	151	17	.	.	PUNCT
ajlm-1975	152	1	the	the	DET
ajlm-1975	152	2	data	datum	NOUN
ajlm-1975	152	3	from	from	ADP
ajlm-1975	152	4	the	the	DET
ajlm-1975	152	5	susceptible	susceptible	ADJ
ajlm-1975	152	6	tuberculosis	tuberculosis	NOUN
ajlm-1975	152	7	treatment	treatment	NOUN
ajlm-1975	152	8	register	register	NOUN
ajlm-1975	152	9	was	be	AUX
ajlm-1975	152	10	not	not	PART
ajlm-1975	152	11	available	available	ADJ
ajlm-1975	152	12	to	to	PART
ajlm-1975	152	13	compare	compare	VERB
ajlm-1975	152	14	with	with	ADP
ajlm-1975	152	15	that	that	PRON
ajlm-1975	152	16	on	on	ADP
ajlm-1975	152	17	the	the	DET
ajlm-1975	152	18	dr	dr	PROPN
ajlm-1975	152	19	-	-	PUNCT
ajlm-1975	152	20	tb	tb	NOUN
ajlm-1975	152	21	register	register	VERB
ajlm-1975	152	22	to	to	PART
ajlm-1975	152	23	determine	determine	VERB
ajlm-1975	152	24	if	if	SCONJ
ajlm-1975	152	25	patients	patient	NOUN
ajlm-1975	152	26	not	not	PART
ajlm-1975	152	27	listed	list	VERB
ajlm-1975	152	28	on	on	ADP
ajlm-1975	152	29	the	the	DET
ajlm-1975	152	30	dr	dr	PROPN
ajlm-1975	152	31	-	-	PUNCT
ajlm-1975	152	32	tb	tb	NOUN
ajlm-1975	152	33	register	register	NOUN
ajlm-1975	152	34	were	be	AUX
ajlm-1975	152	35	treated	treat	VERB
ajlm-1975	152	36	with	with	ADP
ajlm-1975	152	37	first	first	ADJ
ajlm-1975	152	38	-	-	PUNCT
ajlm-1975	152	39	line	line	NOUN
ajlm-1975	152	40	tuberculosis	tuberculosis	NOUN
ajlm-1975	152	41	therapy	therapy	NOUN
ajlm-1975	152	42	.	.	PUNCT
ajlm-1975	153	1	finally	finally	ADV
ajlm-1975	153	2	,	,	PUNCT
ajlm-1975	153	3	the	the	DET
ajlm-1975	153	4	study	study	NOUN
ajlm-1975	153	5	was	be	AUX
ajlm-1975	153	6	performed	perform	VERB
ajlm-1975	153	7	in	in	ADP
ajlm-1975	153	8	one	one	NUM
ajlm-1975	153	9	province	province	NOUN
ajlm-1975	153	10	of	of	ADP
ajlm-1975	153	11	south	south	PROPN
ajlm-1975	153	12	africa	africa	PROPN
ajlm-1975	153	13	so	so	SCONJ
ajlm-1975	153	14	the	the	DET
ajlm-1975	153	15	findings	finding	NOUN
ajlm-1975	153	16	may	may	AUX
ajlm-1975	153	17	not	not	PART
ajlm-1975	153	18	apply	apply	VERB
ajlm-1975	153	19	to	to	ADP
ajlm-1975	153	20	other	other	ADJ
ajlm-1975	153	21	regions	region	NOUN
ajlm-1975	153	22	.	.	PUNCT
ajlm-1975	154	1	nonetheless	nonetheless	ADV
ajlm-1975	154	2	,	,	PUNCT
ajlm-1975	154	3	this	this	DET
ajlm-1975	154	4	province	province	NOUN
ajlm-1975	154	5	has	have	VERB
ajlm-1975	154	6	the	the	DET
ajlm-1975	154	7	highest	high	ADJ
ajlm-1975	154	8	prevalence	prevalence	NOUN
ajlm-1975	154	9	of	of	ADP
ajlm-1975	154	10	dr	dr	PROPN
ajlm-1975	154	11	-	-	PUNCT
ajlm-1975	154	12	tb	tb	NOUN
ajlm-1975	154	13	cases	case	NOUN
ajlm-1975	154	14	in	in	ADP
ajlm-1975	154	15	the	the	DET
ajlm-1975	154	16	country	country	NOUN
ajlm-1975	154	17	and	and	CCONJ
ajlm-1975	154	18	similar	similar	ADJ
ajlm-1975	154	19	findings	finding	NOUN
ajlm-1975	154	20	have	have	AUX
ajlm-1975	154	21	been	be	AUX
ajlm-1975	154	22	reported	report	VERB
ajlm-1975	154	23	in	in	ADP
ajlm-1975	154	24	the	the	DET
ajlm-1975	154	25	northern	northern	ADJ
ajlm-1975	154	26	provinces	province	NOUN
ajlm-1975	154	27	.	.	PUNCT
ajlm-1975	155	1	conclusion	conclusion	VERB
ajlm-1975	155	2	the	the	DET
ajlm-1975	155	3	presence	presence	NOUN
ajlm-1975	155	4	of	of	ADP
ajlm-1975	155	5	highly	highly	ADV
ajlm-1975	155	6	drug	drug	NOUN
ajlm-1975	155	7	-	-	PUNCT
ajlm-1975	155	8	resistant	resistant	ADJ
ajlm-1975	155	9	m.	m.	NOUN
ajlm-1975	155	10	tuberculosis	tuberculosis	NOUN
ajlm-1975	155	11	strains	strain	NOUN
ajlm-1975	155	12	with	with	ADP
ajlm-1975	155	13	mutations	mutation	NOUN
ajlm-1975	155	14	missed	miss	VERB
ajlm-1975	155	15	by	by	ADP
ajlm-1975	155	16	the	the	DET
ajlm-1975	155	17	routine	routine	ADJ
ajlm-1975	155	18	rapid	rapid	ADJ
ajlm-1975	155	19	molecular	molecular	ADJ
ajlm-1975	155	20	assays	assay	NOUN
ajlm-1975	155	21	highlights	highlight	NOUN
ajlm-1975	155	22	the	the	DET
ajlm-1975	155	23	need	need	NOUN
ajlm-1975	155	24	for	for	ADP
ajlm-1975	155	25	the	the	DET
ajlm-1975	155	26	revision	revision	NOUN
ajlm-1975	155	27	of	of	ADP
ajlm-1975	155	28	the	the	DET
ajlm-1975	155	29	who	who	PRON
ajlm-1975	155	30	definition	definition	NOUN
ajlm-1975	155	31	of	of	ADP
ajlm-1975	155	32	universal	universal	ADJ
ajlm-1975	155	33	access	access	NOUN
ajlm-1975	155	34	to	to	ADP
ajlm-1975	155	35	dst	dst	PROPN
ajlm-1975	155	36	so	so	SCONJ
ajlm-1975	155	37	that	that	SCONJ
ajlm-1975	155	38	tuberculosis	tuberculosis	NOUN
ajlm-1975	155	39	diagnostic	diagnostic	ADJ
ajlm-1975	155	40	algorithms	algorithm	NOUN
ajlm-1975	155	41	include	include	VERB
ajlm-1975	155	42	testing	test	VERB
ajlm-1975	155	43	for	for	ADP
ajlm-1975	155	44	both	both	DET
ajlm-1975	155	45	isoniazid	isoniazid	NOUN
ajlm-1975	155	46	and	and	CCONJ
ajlm-1975	155	47	rifampicin	rifampicin	VERB
ajlm-1975	155	48	in	in	ADP
ajlm-1975	155	49	all	all	DET
ajlm-1975	155	50	patients	patient	NOUN
ajlm-1975	155	51	with	with	ADP
ajlm-1975	155	52	bacteriologically	bacteriologically	ADV
ajlm-1975	155	53	confirmed	confirm	VERB
ajlm-1975	155	54	tuberculosis	tuberculosis	NOUN
ajlm-1975	155	55	.	.	PUNCT
ajlm-1975	156	1	the	the	DET
ajlm-1975	156	2	recent	recent	ADJ
ajlm-1975	156	3	endorsement	endorsement	NOUN
ajlm-1975	156	4	of	of	ADP
ajlm-1975	156	5	the	the	DET
ajlm-1975	156	6	xpert	xpert	PROPN
ajlm-1975	156	7	mtb	mtb	PROPN
ajlm-1975	156	8	/	/	SYM
ajlm-1975	156	9	xdr	xdr	PROPN
ajlm-1975	156	10	by	by	ADP
ajlm-1975	156	11	the	the	DET
ajlm-1975	156	12	who	who	PRON
ajlm-1975	156	13	for	for	ADP
ajlm-1975	156	14	detection	detection	NOUN
ajlm-1975	156	15	of	of	ADP
ajlm-1975	156	16	isoniazid	isoniazid	NOUN
ajlm-1975	156	17	,	,	PUNCT
ajlm-1975	156	18	fluoroquinolone	fluoroquinolone	NOUN
ajlm-1975	156	19	and	and	CCONJ
ajlm-1975	156	20	second	second	ADJ
ajlm-1975	156	21	-	-	PUNCT
ajlm-1975	156	22	line	line	NOUN
ajlm-1975	156	23	injectable	injectable	ADJ
ajlm-1975	156	24	agent	agent	NOUN
ajlm-1975	156	25	resistance	resistance	NOUN
ajlm-1975	156	26	in	in	ADP
ajlm-1975	156	27	xpert	xpert	PROPN
ajlm-1975	156	28	(	(	PUNCT
ajlm-1975	156	29	ultra)-confirmed	ultra)-confirmed	ADJ
ajlm-1975	156	30	tuberculosis	tuberculosis	NOUN
ajlm-1975	156	31	cases	case	NOUN
ajlm-1975	156	32	provides	provide	VERB
ajlm-1975	156	33	an	an	DET
ajlm-1975	156	34	opportunity	opportunity	NOUN
ajlm-1975	156	35	to	to	PART
ajlm-1975	156	36	close	close	VERB
ajlm-1975	156	37	the	the	DET
ajlm-1975	156	38	gap	gap	NOUN
ajlm-1975	156	39	in	in	ADP
ajlm-1975	156	40	isoniazid	isoniazid	NOUN
ajlm-1975	156	41	testing.1	testing.1	ADP
ajlm-1975	156	42	the	the	DET
ajlm-1975	156	43	i491f	i491f	PROPN
ajlm-1975	156	44	mutation	mutation	NOUN
ajlm-1975	156	45	remains	remain	VERB
ajlm-1975	156	46	the	the	DET
ajlm-1975	156	47	most	most	ADV
ajlm-1975	156	48	commonly	commonly	ADV
ajlm-1975	156	49	detected	detect	VERB
ajlm-1975	156	50	mutation	mutation	NOUN
ajlm-1975	156	51	outside	outside	ADP
ajlm-1975	156	52	the	the	DET
ajlm-1975	156	53	rrdr	rrdr	NOUN
ajlm-1975	156	54	and	and	CCONJ
ajlm-1975	156	55	its	its	PRON
ajlm-1975	156	56	frequent	frequent	ADJ
ajlm-1975	156	57	occurrence	occurrence	NOUN
ajlm-1975	156	58	in	in	ADP
ajlm-1975	156	59	isoniazid	isoniazid	NOUN
ajlm-1975	156	60	-	-	PUNCT
ajlm-1975	156	61	resistant	resistant	ADJ
ajlm-1975	156	62	cases	case	NOUN
ajlm-1975	156	63	calls	call	VERB
ajlm-1975	156	64	for	for	ADP
ajlm-1975	156	65	its	its	PRON
ajlm-1975	156	66	inclusion	inclusion	NOUN
ajlm-1975	156	67	in	in	ADP
ajlm-1975	156	68	assays	assay	NOUN
ajlm-1975	156	69	that	that	PRON
ajlm-1975	156	70	detect	detect	VERB
ajlm-1975	156	71	rifampicin	rifampicin	VERB
ajlm-1975	156	72	resistance	resistance	NOUN
ajlm-1975	156	73	.	.	PUNCT
ajlm-1975	157	1	this	this	DET
ajlm-1975	157	2	codon	codon	NOUN
ajlm-1975	157	3	is	be	AUX
ajlm-1975	157	4	not	not	PART
ajlm-1975	157	5	too	too	ADV
ajlm-1975	157	6	far	far	ADV
ajlm-1975	157	7	away	away	ADV
ajlm-1975	157	8	from	from	ADP
ajlm-1975	157	9	the	the	DET
ajlm-1975	157	10	rrdr	rrdr	NOUN
ajlm-1975	157	11	,	,	PUNCT
ajlm-1975	157	12	so	so	ADV
ajlm-1975	157	13	current	current	ADJ
ajlm-1975	157	14	assays	assay	NOUN
ajlm-1975	157	15	can	can	AUX
ajlm-1975	157	16	be	be	AUX
ajlm-1975	157	17	upgraded	upgrade	VERB
ajlm-1975	157	18	to	to	PART
ajlm-1975	157	19	include	include	VERB
ajlm-1975	157	20	it	it	PRON
ajlm-1975	157	21	to	to	PART
ajlm-1975	157	22	avoid	avoid	VERB
ajlm-1975	157	23	the	the	DET
ajlm-1975	157	24	use	use	NOUN
ajlm-1975	157	25	of	of	ADP
ajlm-1975	157	26	inappropriate	inappropriate	ADJ
ajlm-1975	157	27	therapy	therapy	NOUN
ajlm-1975	157	28	,	,	PUNCT
ajlm-1975	157	29	prevent	prevent	VERB
ajlm-1975	157	30	the	the	DET
ajlm-1975	157	31	accumulation	accumulation	NOUN
ajlm-1975	157	32	of	of	ADP
ajlm-1975	157	33	resistance	resistance	NOUN
ajlm-1975	157	34	,	,	PUNCT
ajlm-1975	157	35	and	and	CCONJ
ajlm-1975	157	36	reduce	reduce	VERB
ajlm-1975	157	37	community	community	NOUN
ajlm-1975	157	38	spread	spread	NOUN
ajlm-1975	157	39	.	.	PUNCT
ajlm-1975	158	1	acknowledgements	acknowledgement	NOUN
ajlm-1975	158	2	the	the	DET
ajlm-1975	158	3	authors	author	NOUN
ajlm-1975	158	4	would	would	AUX
ajlm-1975	158	5	like	like	VERB
ajlm-1975	158	6	to	to	PART
ajlm-1975	158	7	thank	thank	VERB
ajlm-1975	158	8	the	the	DET
ajlm-1975	158	9	national	national	PROPN
ajlm-1975	158	10	health	health	PROPN
ajlm-1975	158	11	laboratory	laboratory	PROPN
ajlm-1975	158	12	service	service	NOUN
ajlm-1975	158	13	tuberculosis	tuberculosis	NOUN
ajlm-1975	158	14	laboratory	laboratory	NOUN
ajlm-1975	158	15	staff	staff	NOUN
ajlm-1975	158	16	at	at	ADP
ajlm-1975	158	17	the	the	DET
ajlm-1975	158	18	inkosi	inkosi	PROPN
ajlm-1975	158	19	albert	albert	PROPN
ajlm-1975	158	20	luthuli	luthuli	PROPN
ajlm-1975	158	21	central	central	PROPN
ajlm-1975	158	22	hospital	hospital	NOUN
ajlm-1975	158	23	who	who	PRON
ajlm-1975	158	24	performed	perform	VERB
ajlm-1975	158	25	the	the	DET
ajlm-1975	158	26	routine	routine	ADJ
ajlm-1975	158	27	clinical	clinical	ADJ
ajlm-1975	158	28	work	work	NOUN
ajlm-1975	158	29	for	for	ADP
ajlm-1975	158	30	the	the	DET
ajlm-1975	158	31	province	province	NOUN
ajlm-1975	158	32	of	of	ADP
ajlm-1975	158	33	kwazulu	kwazulu	PROPN
ajlm-1975	158	34	-	-	PUNCT
ajlm-1975	158	35	natal	natal	NOUN
ajlm-1975	158	36	.	.	PUNCT
ajlm-1975	159	1	competing	compete	VERB
ajlm-1975	159	2	interests	interest	NOUN
ajlm-1975	159	3	the	the	DET
ajlm-1975	159	4	authors	author	NOUN
ajlm-1975	159	5	declare	declare	VERB
ajlm-1975	159	6	that	that	SCONJ
ajlm-1975	159	7	they	they	PRON
ajlm-1975	159	8	have	have	VERB
ajlm-1975	159	9	no	no	DET
ajlm-1975	159	10	financial	financial	ADJ
ajlm-1975	159	11	or	or	CCONJ
ajlm-1975	159	12	personal	personal	ADJ
ajlm-1975	159	13	relationships	relationship	NOUN
ajlm-1975	159	14	that	that	PRON
ajlm-1975	159	15	may	may	AUX
ajlm-1975	159	16	have	have	AUX
ajlm-1975	159	17	inappropriately	inappropriately	ADV
ajlm-1975	159	18	influenced	influence	VERB
ajlm-1975	159	19	them	they	PRON
ajlm-1975	159	20	in	in	ADP
ajlm-1975	159	21	writing	write	VERB
ajlm-1975	159	22	this	this	DET
ajlm-1975	159	23	article	article	NOUN
ajlm-1975	159	24	.	.	PUNCT
ajlm-1975	160	1	authors	author	NOUN
ajlm-1975	160	2	’	’	PART
ajlm-1975	160	3	contributions	contribution	NOUN
ajlm-1975	160	4	n.r.m	n.r.m	NOUN
ajlm-1975	160	5	.	.	PUNCT
ajlm-1975	161	1	and	and	CCONJ
ajlm-1975	161	2	k.p.m	k.p.m	PROPN
ajlm-1975	161	3	.	.	PROPN
ajlm-1975	161	4	were	be	AUX
ajlm-1975	161	5	involved	involve	VERB
ajlm-1975	161	6	in	in	ADP
ajlm-1975	161	7	the	the	DET
ajlm-1975	161	8	original	original	ADJ
ajlm-1975	161	9	conceptualisation	conceptualisation	NOUN
ajlm-1975	161	10	of	of	ADP
ajlm-1975	161	11	the	the	DET
ajlm-1975	161	12	study	study	NOUN
ajlm-1975	161	13	as	as	ADV
ajlm-1975	161	14	well	well	ADV
ajlm-1975	161	15	as	as	ADP
ajlm-1975	161	16	obtaining	obtain	VERB
ajlm-1975	161	17	the	the	DET
ajlm-1975	161	18	study	study	NOUN
ajlm-1975	161	19	funding	funding	NOUN
ajlm-1975	161	20	.	.	PUNCT
ajlm-1975	162	1	n.r.m	n.r.m	NOUN
ajlm-1975	162	2	.	.	PUNCT
ajlm-1975	162	3	also	also	ADV
ajlm-1975	162	4	carried	carry	VERB
ajlm-1975	162	5	out	out	ADP
ajlm-1975	162	6	laboratory	laboratory	NOUN
ajlm-1975	162	7	work	work	NOUN
ajlm-1975	162	8	,	,	PUNCT
ajlm-1975	162	9	data	datum	NOUN
ajlm-1975	162	10	acquisition	acquisition	NOUN
ajlm-1975	162	11	and	and	CCONJ
ajlm-1975	162	12	analysis	analysis	NOUN
ajlm-1975	162	13	,	,	PUNCT
ajlm-1975	162	14	project	project	NOUN
ajlm-1975	162	15	administration	administration	NOUN
ajlm-1975	162	16	and	and	CCONJ
ajlm-1975	162	17	writing	writing	NOUN
ajlm-1975	162	18	of	of	ADP
ajlm-1975	162	19	the	the	DET
ajlm-1975	162	20	manuscript	manuscript	NOUN
ajlm-1975	162	21	.	.	PUNCT
ajlm-1975	163	1	l.p.c	l.p.c	PROPN
ajlm-1975	163	2	.	.	PUNCT
ajlm-1975	164	1	performed	perform	VERB
ajlm-1975	164	2	the	the	DET
ajlm-1975	164	3	data	datum	NOUN
ajlm-1975	164	4	analysis	analysis	NOUN
ajlm-1975	164	5	and	and	CCONJ
ajlm-1975	164	6	writing	writing	NOUN
ajlm-1975	164	7	of	of	ADP
ajlm-1975	164	8	the	the	DET
ajlm-1975	164	9	manuscript	manuscript	NOUN
ajlm-1975	164	10	.	.	PUNCT
ajlm-1975	165	1	r.s	r.s	PROPN
ajlm-1975	165	2	.	.	PROPN
ajlm-1975	165	3	was	be	AUX
ajlm-1975	165	4	involved	involve	VERB
ajlm-1975	165	5	in	in	ADP
ajlm-1975	165	6	performing	perform	VERB
ajlm-1975	165	7	laboratory	laboratory	NOUN
ajlm-1975	165	8	work	work	NOUN
ajlm-1975	165	9	.	.	PUNCT
ajlm-1975	166	1	y.n	y.n	PROPN
ajlm-1975	166	2	.	.	PROPN
ajlm-1975	167	1	and	and	CCONJ
ajlm-1975	167	2	j.g	j.g	PROPN
ajlm-1975	167	3	.	.	PROPN
ajlm-1975	167	4	performed	perform	VERB
ajlm-1975	167	5	whole	whole	ADJ
ajlm-1975	167	6	-	-	PUNCT
ajlm-1975	167	7	genome	genome	NOUN
ajlm-1975	167	8	sequencing	sequencing	NOUN
ajlm-1975	167	9	.	.	PUNCT
ajlm-1975	168	1	e.w	e.w	AUX
ajlm-1975	168	2	.	.	PROPN
ajlm-1975	168	3	did	do	VERB
ajlm-1975	168	4	the	the	DET
ajlm-1975	168	5	whole	whole	ADJ
ajlm-1975	168	6	-	-	PUNCT
ajlm-1975	168	7	genome	genome	NOUN
ajlm-1975	168	8	sequencing	sequencing	NOUN
ajlm-1975	168	9	analysis	analysis	NOUN
ajlm-1975	168	10	.	.	PUNCT
ajlm-1975	169	1	t.d.o	t.d.o	PROPN
ajlm-1975	169	2	.	.	PUNCT
ajlm-1975	169	3	supervised	supervise	VERB
ajlm-1975	169	4	the	the	DET
ajlm-1975	169	5	overall	overall	ADJ
ajlm-1975	169	6	whole	whole	ADJ
ajlm-1975	169	7	-	-	PUNCT
ajlm-1975	169	8	genome	genome	NOUN
ajlm-1975	169	9	sequencing	sequence	VERB
ajlm-1975	169	10	work	work	NOUN
ajlm-1975	169	11	.	.	PUNCT
ajlm-1975	170	1	k.s.s.-h	k.s.s.-h	PROPN
ajlm-1975	170	2	.	.	PROPN
ajlm-1975	170	3	assisted	assist	VERB
ajlm-1975	170	4	with	with	ADP
ajlm-1975	170	5	the	the	DET
ajlm-1975	170	6	writing	writing	NOUN
ajlm-1975	170	7	and	and	CCONJ
ajlm-1975	170	8	reviewing	reviewing	NOUN
ajlm-1975	170	9	of	of	ADP
ajlm-1975	170	10	the	the	DET
ajlm-1975	170	11	manuscript	manuscript	NOUN
ajlm-1975	170	12	and	and	CCONJ
ajlm-1975	170	13	k.p.m	k.p.m	PROPN
ajlm-1975	170	14	.	.	PUNCT
ajlm-1975	171	1	was	be	AUX
ajlm-1975	171	2	the	the	DET
ajlm-1975	171	3	overall	overall	ADJ
ajlm-1975	171	4	supervisor	supervisor	NOUN
ajlm-1975	171	5	of	of	ADP
ajlm-1975	171	6	the	the	DET
ajlm-1975	171	7	project	project	NOUN
ajlm-1975	171	8	including	include	VERB
ajlm-1975	171	9	the	the	DET
ajlm-1975	171	10	writing	writing	NOUN
ajlm-1975	171	11	of	of	ADP
ajlm-1975	171	12	the	the	DET
ajlm-1975	171	13	manuscript	manuscript	NOUN
ajlm-1975	171	14	.	.	PUNCT
ajlm-1975	172	1	sources	source	NOUN
ajlm-1975	172	2	of	of	ADP
ajlm-1975	172	3	support	support	NOUN
ajlm-1975	172	4	this	this	DET
ajlm-1975	172	5	work	work	NOUN
ajlm-1975	172	6	was	be	AUX
ajlm-1975	172	7	supported	support	VERB
ajlm-1975	172	8	by	by	ADP
ajlm-1975	172	9	the	the	DET
ajlm-1975	172	10	university	university	NOUN
ajlm-1975	172	11	capacity	capacity	NOUN
ajlm-1975	172	12	development	development	NOUN
ajlm-1975	172	13	programme	programme	NOUN
ajlm-1975	172	14	of	of	ADP
ajlm-1975	172	15	the	the	DET
ajlm-1975	172	16	university	university	NOUN
ajlm-1975	172	17	of	of	ADP
ajlm-1975	172	18	kwazulu	kwazulu	PROPN
ajlm-1975	172	19	-	-	PUNCT
ajlm-1975	172	20	natal	natal	NOUN
ajlm-1975	172	21	and	and	CCONJ
ajlm-1975	172	22	the	the	DET
ajlm-1975	172	23	national	national	PROPN
ajlm-1975	172	24	health	health	PROPN
ajlm-1975	172	25	laboratory	laboratory	PROPN
ajlm-1975	172	26	service	service	PROPN
ajlm-1975	172	27	research	research	PROPN
ajlm-1975	172	28	trust	trust	PROPN
ajlm-1975	172	29	.	.	PUNCT
ajlm-1975	173	1	data	datum	NOUN
ajlm-1975	173	2	availability	availability	NOUN
ajlm-1975	173	3	all	all	DET
ajlm-1975	173	4	data	datum	NOUN
ajlm-1975	173	5	generated	generate	VERB
ajlm-1975	173	6	from	from	ADP
ajlm-1975	173	7	this	this	DET
ajlm-1975	173	8	study	study	NOUN
ajlm-1975	173	9	are	be	AUX
ajlm-1975	173	10	available	available	ADJ
ajlm-1975	173	11	on	on	ADP
ajlm-1975	173	12	request	request	NOUN
ajlm-1975	173	13	from	from	ADP
ajlm-1975	173	14	the	the	DET
ajlm-1975	173	15	corresponding	corresponding	ADJ
ajlm-1975	173	16	author	author	NOUN
ajlm-1975	173	17	,	,	PUNCT
ajlm-1975	173	18	n.r.m	n.r.m	PROPN
ajlm-1975	173	19	.	.	PUNCT
ajlm-1975	174	1	disclaimer	disclaimer	NOUN
ajlm-1975	174	2	the	the	DET
ajlm-1975	174	3	views	view	NOUN
ajlm-1975	174	4	expressed	express	VERB
ajlm-1975	174	5	in	in	ADP
ajlm-1975	174	6	this	this	DET
ajlm-1975	174	7	manuscript	manuscript	NOUN
ajlm-1975	174	8	are	be	AUX
ajlm-1975	174	9	those	those	PRON
ajlm-1975	174	10	of	of	ADP
ajlm-1975	174	11	the	the	DET
ajlm-1975	174	12	authors	author	NOUN
ajlm-1975	174	13	and	and	CCONJ
ajlm-1975	174	14	not	not	PART
ajlm-1975	174	15	an	an	DET
ajlm-1975	174	16	official	official	ADJ
ajlm-1975	174	17	position	position	NOUN
ajlm-1975	174	18	of	of	ADP
ajlm-1975	174	19	the	the	DET
ajlm-1975	174	20	institutions	institution	NOUN
ajlm-1975	174	21	involved	involve	VERB
ajlm-1975	174	22	or	or	CCONJ
ajlm-1975	174	23	any	any	DET
ajlm-1975	174	24	funders	funder	NOUN
ajlm-1975	174	25	.	.	PUNCT
ajlm-1975	175	1	references	reference	NOUN
ajlm-1975	175	2	who	who	PRON
ajlm-1975	175	3	.	.	PUNCT
ajlm-1975	176	1	who	who	PRON
ajlm-1975	176	2	operational	operational	ADJ
ajlm-1975	176	3	handbook	handbook	NOUN
ajlm-1975	176	4	on	on	ADP
ajlm-1975	176	5	tuberculosis	tuberculosis	NOUN
ajlm-1975	176	6	.	.	PUNCT
ajlm-1975	177	1	module	module	NOUN
ajlm-1975	177	2	3	3	NUM
ajlm-1975	177	3	:	:	PUNCT
ajlm-1975	177	4	diagnosis	diagnosis	NOUN
ajlm-1975	177	5	–	–	PUNCT
ajlm-1975	177	6	rapid	rapid	ADJ
ajlm-1975	177	7	diagnostics	diagnostic	NOUN
ajlm-1975	177	8	for	for	ADP
ajlm-1975	177	9	tuberculosis	tuberculosis	NOUN
ajlm-1975	177	10	detention	detention	NOUN
ajlm-1975	177	11	,	,	PUNCT
ajlm-1975	177	12	2021	2021	NUM
ajlm-1975	177	13	update	update	NOUN
ajlm-1975	177	14	.	.	PUNCT
ajlm-1975	178	1	geneva	geneva	NOUN
ajlm-1975	178	2	:	:	PUNCT
ajlm-1975	178	3	world	world	PROPN
ajlm-1975	178	4	health	health	NOUN
ajlm-1975	178	5	organization	organization	NOUN
ajlm-1975	178	6	;	;	PUNCT
ajlm-1975	178	7	2021	2021	NUM
ajlm-1975	178	8	.	.	PUNCT
ajlm-1975	179	1	who	who	PRON
ajlm-1975	179	2	.	.	PUNCT
ajlm-1975	180	1	molecular	molecular	ADJ
ajlm-1975	180	2	line	line	NOUN
ajlm-1975	180	3	probe	probe	NOUN
ajlm-1975	180	4	assays	assay	NOUN
ajlm-1975	180	5	for	for	ADP
ajlm-1975	180	6	rapid	rapid	ADJ
ajlm-1975	180	7	screening	screening	NOUN
ajlm-1975	180	8	of	of	ADP
ajlm-1975	180	9	patients	patient	NOUN
ajlm-1975	180	10	at	at	ADP
ajlm-1975	180	11	risk	risk	NOUN
ajlm-1975	180	12	of	of	ADP
ajlm-1975	180	13	multidrug	multidrug	NOUN
ajlm-1975	180	14	-	-	PUNCT
ajlm-1975	180	15	resistant	resistant	ADJ
ajlm-1975	180	16	tuberculosis	tuberculosis	NOUN
ajlm-1975	180	17	(	(	PUNCT
ajlm-1975	180	18	mdr	mdr	NOUN
ajlm-1975	180	19	-	-	NOUN
ajlm-1975	180	20	tb	tb	NOUN
ajlm-1975	180	21	)	)	PUNCT
ajlm-1975	180	22	.	.	PUNCT
ajlm-1975	181	1	geneva	geneva	PROPN
ajlm-1975	181	2	:	:	PUNCT
ajlm-1975	181	3	world	world	PROPN
ajlm-1975	181	4	health	health	PROPN
ajlm-1975	181	5	organization	organization	NOUN
ajlm-1975	181	6	;	;	PUNCT
ajlm-1975	181	7	2008	2008	NUM
ajlm-1975	181	8	.	.	PUNCT
ajlm-1975	182	1	who	who	PRON
ajlm-1975	182	2	.	.	PUNCT
ajlm-1975	183	1	automated	automate	VERB
ajlm-1975	183	2	real	real	ADJ
ajlm-1975	183	3	-	-	PUNCT
ajlm-1975	183	4	time	time	NOUN
ajlm-1975	183	5	nucleic	nucleic	ADJ
ajlm-1975	183	6	acid	acid	NOUN
ajlm-1975	183	7	amplification	amplification	NOUN
ajlm-1975	183	8	technology	technology	NOUN
ajlm-1975	183	9	for	for	ADP
ajlm-1975	183	10	rapid	rapid	ADJ
ajlm-1975	183	11	and	and	CCONJ
ajlm-1975	183	12	simultaneous	simultaneous	ADJ
ajlm-1975	183	13	detection	detection	NOUN
ajlm-1975	183	14	of	of	ADP
ajlm-1975	183	15	tuberculosis	tuberculosis	NOUN
ajlm-1975	183	16	and	and	CCONJ
ajlm-1975	183	17	rifampicin	rifampicin	VERB
ajlm-1975	183	18	resistance	resistance	NOUN
ajlm-1975	183	19	:	:	PUNCT
ajlm-1975	183	20	xpert	xpert	PROPN
ajlm-1975	183	21	mtb	mtb	PROPN
ajlm-1975	183	22	/	/	SYM
ajlm-1975	183	23	rif	rif	PROPN
ajlm-1975	183	24	system	system	NOUN
ajlm-1975	183	25	.	.	PUNCT
ajlm-1975	184	1	policy	policy	NOUN
ajlm-1975	184	2	statement	statement	NOUN
ajlm-1975	184	3	.	.	PUNCT
ajlm-1975	185	1	geneva	geneva	PROPN
ajlm-1975	185	2	:	:	PUNCT
ajlm-1975	185	3	world	world	PROPN
ajlm-1975	185	4	health	health	NOUN
ajlm-1975	185	5	organization	organization	NOUN
ajlm-1975	185	6	;	;	PUNCT
ajlm-1975	185	7	2011	2011	NUM
ajlm-1975	185	8	.	.	PUNCT
ajlm-1975	186	1	andre	andre	PROPN
ajlm-1975	186	2	e	e	PROPN
ajlm-1975	186	3	,	,	PUNCT
ajlm-1975	186	4	goeminne	goeminne	PROPN
ajlm-1975	186	5	l	l	PROPN
ajlm-1975	186	6	,	,	PUNCT
ajlm-1975	186	7	cabibbe	cabibbe	NOUN
ajlm-1975	186	8	a	a	X
ajlm-1975	186	9	,	,	PUNCT
ajlm-1975	186	10	et	et	PROPN
ajlm-1975	186	11	al	al	PROPN
ajlm-1975	186	12	.	.	PUNCT
ajlm-1975	187	1	consensus	consensus	NOUN
ajlm-1975	187	2	numbering	number	VERB
ajlm-1975	187	3	system	system	NOUN
ajlm-1975	187	4	for	for	ADP
ajlm-1975	187	5	the	the	DET
ajlm-1975	187	6	rifampicin	rifampicin	VERB
ajlm-1975	187	7	resistance	resistance	NOUN
ajlm-1975	187	8	-	-	PUNCT
ajlm-1975	187	9	associated	associate	VERB
ajlm-1975	187	10	rpob	rpob	ADJ
ajlm-1975	187	11	gene	gene	NOUN
ajlm-1975	187	12	mutations	mutation	NOUN
ajlm-1975	187	13	in	in	ADP
ajlm-1975	187	14	pathogenic	pathogenic	ADJ
ajlm-1975	187	15	mycobacteria	mycobacterium	NOUN
ajlm-1975	187	16	.	.	PUNCT
ajlm-1975	188	1	clin	clin	PROPN
ajlm-1975	188	2	microbiol	microbiol	PROPN
ajlm-1975	188	3	infect	infect	VERB
ajlm-1975	188	4	.	.	PUNCT
ajlm-1975	189	1	2017;23(3):167–172	2017;23(3):167–172	NUM
ajlm-1975	189	2	.	.	PUNCT
ajlm-1975	190	1	https://doi.org/10.1016/j.cmi.2016.09.006	https://doi.org/10.1016/j.cmi.2016.09.006	ADJ
ajlm-1975	190	2	telenti	telenti	NOUN
ajlm-1975	190	3	a	a	NOUN
ajlm-1975	190	4	,	,	PUNCT
ajlm-1975	190	5	imboden	imboden	ADJ
ajlm-1975	190	6	p.	p.	NOUN
ajlm-1975	190	7	detection	detection	NOUN
ajlm-1975	190	8	of	of	ADP
ajlm-1975	190	9	rifampicin	rifampicin	VERB
ajlm-1975	190	10	-	-	PUNCT
ajlm-1975	190	11	resistance	resistance	NOUN
ajlm-1975	190	12	mutations	mutation	NOUN
ajlm-1975	190	13	in	in	ADP
ajlm-1975	190	14	mycobacterium	mycobacterium	NOUN
ajlm-1975	190	15	tuberculosis	tuberculosis	NOUN
ajlm-1975	190	16	.	.	PUNCT
ajlm-1975	191	1	lancet	lancet	PROPN
ajlm-1975	191	2	.	.	PUNCT
ajlm-1975	192	1	1993;341(8846):647–650	1993;341(8846):647–650	X
ajlm-1975	192	2	.	.	PUNCT
ajlm-1975	193	1	https://doi.org/10.1016/0140-6736(93)90417-f	https://doi.org/10.1016/0140-6736(93)90417-f	PROPN
ajlm-1975	193	2	ng	ng	PROPN
ajlm-1975	193	3	kcs	kcs	PROPN
ajlm-1975	193	4	,	,	PUNCT
ajlm-1975	193	5	supply	supply	NOUN
ajlm-1975	193	6	p	p	NOUN
ajlm-1975	193	7	,	,	PUNCT
ajlm-1975	193	8	cobelens	cobelen	VERB
ajlm-1975	193	9	fgj	fgj	NOUN
ajlm-1975	193	10	,	,	PUNCT
ajlm-1975	193	11	et	et	PROPN
ajlm-1975	193	12	al	al	PROPN
ajlm-1975	193	13	.	.	PUNCT
ajlm-1975	194	1	how	how	SCONJ
ajlm-1975	194	2	well	well	ADV
ajlm-1975	194	3	do	do	AUX
ajlm-1975	194	4	routine	routine	VERB
ajlm-1975	194	5	molecular	molecular	ADJ
ajlm-1975	194	6	diagnostics	diagnostic	NOUN
ajlm-1975	194	7	detect	detect	VERB
ajlm-1975	194	8	rifampin	rifampin	NOUN
ajlm-1975	194	9	heteroresistance	heteroresistance	NOUN
ajlm-1975	194	10	in	in	ADP
ajlm-1975	194	11	mycobacterium	mycobacterium	NOUN
ajlm-1975	194	12	tuberculosis	tuberculosis	NOUN
ajlm-1975	194	13	?	?	PUNCT
ajlm-1975	195	1	j	j	PROPN
ajlm-1975	195	2	clin	clin	PROPN
ajlm-1975	195	3	microbiol	microbiol	PROPN
ajlm-1975	195	4	.	.	PUNCT
ajlm-1975	196	1	2019;57(11):e00717	2019;57(11):e00717	PROPN
ajlm-1975	196	2	–	–	PUNCT
ajlm-1975	196	3	e00719	e00719	PROPN
ajlm-1975	196	4	.	.	PUNCT
ajlm-1975	197	1	https://doi.org/10.1128/jcm.00717-19	https://doi.org/10.1128/jcm.00717-19	PROPN
ajlm-1975	197	2	siu	siu	PROPN
ajlm-1975	197	3	gkh	gkh	PROPN
ajlm-1975	197	4	,	,	PUNCT
ajlm-1975	197	5	zhang	zhang	PROPN
ajlm-1975	197	6	y	y	PROPN
ajlm-1975	197	7	,	,	PUNCT
ajlm-1975	197	8	lau	lau	PROPN
ajlm-1975	197	9	tck	tck	PROPN
ajlm-1975	197	10	,	,	PUNCT
ajlm-1975	197	11	et	et	PROPN
ajlm-1975	197	12	al	al	PROPN
ajlm-1975	197	13	.	.	PUNCT
ajlm-1975	197	14	mutations	mutation	NOUN
ajlm-1975	197	15	outside	outside	ADP
ajlm-1975	197	16	the	the	DET
ajlm-1975	197	17	rifampicin	rifampicin	VERB
ajlm-1975	197	18	resistance	resistance	NOUN
ajlm-1975	197	19	-	-	PUNCT
ajlm-1975	197	20	determining	determine	VERB
ajlm-1975	197	21	region	region	NOUN
ajlm-1975	197	22	associated	associate	VERB
ajlm-1975	197	23	with	with	ADP
ajlm-1975	197	24	rifampicin	rifampicin	VERB
ajlm-1975	197	25	resistance	resistance	NOUN
ajlm-1975	197	26	in	in	ADP
ajlm-1975	197	27	mycobacterium	mycobacterium	NOUN
ajlm-1975	197	28	tuberculosis	tuberculosis	NOUN
ajlm-1975	197	29	.	.	PUNCT
ajlm-1975	198	1	j	j	PROPN
ajlm-1975	198	2	antimicrob	antimicrob	PROPN
ajlm-1975	198	3	chemother	chemother	PROPN
ajlm-1975	198	4	.	.	PUNCT
ajlm-1975	199	1	2011;66(4):730–733	2011;66(4):730–733	X
ajlm-1975	199	2	.	.	PUNCT
ajlm-1975	200	1	https://doi.org/10.1093/jac/dkq519	https://doi.org/10.1093/jac/dkq519	PROPN
ajlm-1975	200	2	heep	heep	NOUN
ajlm-1975	200	3	m	m	NOUN
ajlm-1975	200	4	,	,	PUNCT
ajlm-1975	200	5	brandstätter	brandstätter	ADJ
ajlm-1975	200	6	b	b	PROPN
ajlm-1975	200	7	,	,	PUNCT
ajlm-1975	200	8	rieger	rieger	PROPN
ajlm-1975	200	9	u	u	PROPN
ajlm-1975	200	10	,	,	PUNCT
ajlm-1975	200	11	et	et	PROPN
ajlm-1975	200	12	al	al	PROPN
ajlm-1975	200	13	.	.	PROPN
ajlm-1975	200	14	frequency	frequency	PROPN
ajlm-1975	200	15	of	of	ADP
ajlm-1975	200	16	rpob	rpob	ADJ
ajlm-1975	200	17	mutations	mutation	NOUN
ajlm-1975	200	18	inside	inside	ADP
ajlm-1975	200	19	and	and	CCONJ
ajlm-1975	200	20	outside	outside	ADP
ajlm-1975	200	21	the	the	DET
ajlm-1975	200	22	cluster	cluster	NOUN
ajlm-1975	200	23	i	i	PRON
ajlm-1975	200	24	region	region	VERB
ajlm-1975	200	25	in	in	ADP
ajlm-1975	200	26	rifampin	rifampin	NOUN
ajlm-1975	200	27	-	-	PUNCT
ajlm-1975	200	28	resistant	resistant	ADJ
ajlm-1975	200	29	clinical	clinical	ADJ
ajlm-1975	200	30	mycobacterium	mycobacterium	NOUN
ajlm-1975	200	31	tuberculosis	tuberculosis	NOUN
ajlm-1975	200	32	isolates	isolate	NOUN
ajlm-1975	200	33	.	.	PUNCT
ajlm-1975	201	1	j	j	PROPN
ajlm-1975	201	2	clin	clin	PROPN
ajlm-1975	201	3	microbiol	microbiol	PROPN
ajlm-1975	201	4	.	.	PUNCT
ajlm-1975	202	1	2001;39(1):107–110	2001;39(1):107–110	PROPN
ajlm-1975	202	2	.	.	PUNCT
ajlm-1975	203	1	https://doi.org/10.1128/jcm.39.1.107-110.2001	https://doi.org/10.1128/jcm.39.1.107-110.2001	PROPN
ajlm-1975	203	2	sanchez	sanchez	PROPN
ajlm-1975	203	3	-	-	PUNCT
ajlm-1975	203	4	padilla	padilla	PROPN
ajlm-1975	203	5	e	e	PROPN
ajlm-1975	203	6	,	,	PUNCT
ajlm-1975	203	7	merker	merker	NOUN
ajlm-1975	203	8	m	m	PROPN
ajlm-1975	203	9	,	,	PUNCT
ajlm-1975	203	10	beckert	beckert	NOUN
ajlm-1975	203	11	p	p	NOUN
ajlm-1975	203	12	,	,	PUNCT
ajlm-1975	203	13	et	et	PROPN
ajlm-1975	203	14	al	al	PROPN
ajlm-1975	203	15	.	.	PUNCT
ajlm-1975	203	16	detection	detection	NOUN
ajlm-1975	203	17	of	of	ADP
ajlm-1975	203	18	drug	drug	NOUN
ajlm-1975	203	19	-	-	PUNCT
ajlm-1975	203	20	resistant	resistant	ADJ
ajlm-1975	203	21	tuberculosis	tuberculosis	NOUN
ajlm-1975	203	22	by	by	ADP
ajlm-1975	203	23	xpert	xpert	PROPN
ajlm-1975	203	24	mtb	mtb	PROPN
ajlm-1975	203	25	/	/	SYM
ajlm-1975	203	26	rif	rif	PROPN
ajlm-1975	203	27	in	in	ADP
ajlm-1975	203	28	swaziland	swaziland	PROPN
ajlm-1975	203	29	.	.	PUNCT
ajlm-1975	204	1	n	n	PROPN
ajlm-1975	204	2	engl	engl	PROPN
ajlm-1975	204	3	j	j	PROPN
ajlm-1975	204	4	med	med	PROPN
ajlm-1975	204	5	.	.	PUNCT
ajlm-1975	205	1	2015;372:1181–1182	2015;372:1181–1182	NUM
ajlm-1975	205	2	.	.	PUNCT
ajlm-1975	206	1	https://doi.org/10.1056/nejmc1413930	https://doi.org/10.1056/nejmc1413930	PROPN
ajlm-1975	206	2	makhado	makhado	VERB
ajlm-1975	206	3	na	na	AUX
ajlm-1975	206	4	,	,	PUNCT
ajlm-1975	206	5	matabane	matabane	NOUN
ajlm-1975	206	6	e	e	NOUN
ajlm-1975	206	7	,	,	PUNCT
ajlm-1975	206	8	faccin	faccin	PROPN
ajlm-1975	206	9	m	m	PROPN
ajlm-1975	206	10	,	,	PUNCT
ajlm-1975	206	11	et	et	PROPN
ajlm-1975	206	12	al	al	PROPN
ajlm-1975	206	13	.	.	PROPN
ajlm-1975	206	14	outbreak	outbreak	NOUN
ajlm-1975	206	15	of	of	ADP
ajlm-1975	206	16	multidrug	multidrug	NOUN
ajlm-1975	206	17	-	-	PUNCT
ajlm-1975	206	18	resistant	resistant	ADJ
ajlm-1975	206	19	tuberculosis	tuberculosis	NOUN
ajlm-1975	206	20	in	in	ADP
ajlm-1975	206	21	south	south	PROPN
ajlm-1975	206	22	africa	africa	PROPN
ajlm-1975	206	23	undetected	undetecte	VERB
ajlm-1975	206	24	by	by	ADP
ajlm-1975	206	25	who	who	PRON
ajlm-1975	206	26	-	-	PUNCT
ajlm-1975	206	27	endorsed	endorse	VERB
ajlm-1975	206	28	commercial	commercial	ADJ
ajlm-1975	206	29	tests	test	NOUN
ajlm-1975	206	30	:	:	PUNCT
ajlm-1975	206	31	an	an	DET
ajlm-1975	206	32	observational	observational	ADJ
ajlm-1975	206	33	study	study	NOUN
ajlm-1975	206	34	.	.	PUNCT
ajlm-1975	207	1	lancet	lancet	PROPN
ajlm-1975	207	2	infect	infect	PROPN
ajlm-1975	207	3	dis	dis	PROPN
ajlm-1975	207	4	.	.	PUNCT
ajlm-1975	208	1	2018;18(12):1350–1359	2018;18(12):1350–1359	X
ajlm-1975	208	2	.	.	PUNCT
ajlm-1975	209	1	https://doi.org/10.1016/s1473-3099(18)30496-1	https://doi.org/10.1016/s1473-3099(18)30496-1	PROPN
ajlm-1975	209	2	van	van	PROPN
ajlm-1975	209	3	deun	deun	PROPN
ajlm-1975	209	4	a	a	NOUN
ajlm-1975	209	5	,	,	PUNCT
ajlm-1975	209	6	barrera	barrera	NOUN
ajlm-1975	209	7	l	l	NOUN
ajlm-1975	209	8	,	,	PUNCT
ajlm-1975	209	9	bastian	bastian	PROPN
ajlm-1975	209	10	i	i	PRON
ajlm-1975	209	11	,	,	PUNCT
ajlm-1975	209	12	et	et	PROPN
ajlm-1975	209	13	al	al	PROPN
ajlm-1975	209	14	.	.	PUNCT
ajlm-1975	210	1	mycobacterium	mycobacterium	NOUN
ajlm-1975	210	2	tuberculosis	tuberculosis	NOUN
ajlm-1975	210	3	strains	strain	VERB
ajlm-1975	210	4	with	with	ADP
ajlm-1975	210	5	highly	highly	ADV
ajlm-1975	210	6	discordant	discordant	ADJ
ajlm-1975	210	7	rifampin	rifampin	NOUN
ajlm-1975	210	8	susceptibility	susceptibility	NOUN
ajlm-1975	210	9	test	test	NOUN
ajlm-1975	210	10	results	result	NOUN
ajlm-1975	210	11	.	.	PUNCT
ajlm-1975	211	1	j	j	PROPN
ajlm-1975	211	2	clin	clin	PROPN
ajlm-1975	211	3	microbiol	microbiol	PROPN
ajlm-1975	211	4	.	.	PUNCT
ajlm-1975	212	1	2009;47(11):3501–3506	2009;47(11):3501–3506	X
ajlm-1975	212	2	.	.	PUNCT
ajlm-1975	213	1	https://doi.org/10.1128/jcm.01209-09	https://doi.org/10.1128/jcm.01209-09	PROPN
ajlm-1975	213	2	torrea	torrea	NOUN
ajlm-1975	213	3	g	g	PROPN
ajlm-1975	213	4	,	,	PUNCT
ajlm-1975	213	5	ng	ng	PROPN
ajlm-1975	213	6	kcs	kcs	PROPN
ajlm-1975	213	7	,	,	PUNCT
ajlm-1975	213	8	van	van	PROPN
ajlm-1975	213	9	deun	deun	PROPN
ajlm-1975	213	10	a	a	NOUN
ajlm-1975	213	11	,	,	PUNCT
ajlm-1975	213	12	et	et	PROPN
ajlm-1975	213	13	al	al	PROPN
ajlm-1975	213	14	.	.	PROPN
ajlm-1975	214	1	variable	variable	ADJ
ajlm-1975	214	2	ability	ability	NOUN
ajlm-1975	214	3	of	of	ADP
ajlm-1975	214	4	rapid	rapid	ADJ
ajlm-1975	214	5	tests	test	NOUN
ajlm-1975	214	6	to	to	PART
ajlm-1975	214	7	detect	detect	VERB
ajlm-1975	214	8	mycobacterium	mycobacterium	NOUN
ajlm-1975	214	9	tuberculosis	tuberculosis	NOUN
ajlm-1975	214	10	rpob	rpob	ADJ
ajlm-1975	214	11	mutations	mutation	NOUN
ajlm-1975	214	12	conferring	confer	VERB
ajlm-1975	214	13	phenotypically	phenotypically	ADV
ajlm-1975	214	14	occult	occult	NOUN
ajlm-1975	214	15	rifampicin	rifampicin	VERB
ajlm-1975	214	16	resistance	resistance	NOUN
ajlm-1975	214	17	.	.	PUNCT
ajlm-1975	215	1	sci	sci	PROPN
ajlm-1975	215	2	rep	rep	PROPN
ajlm-1975	215	3	.	.	PROPN
ajlm-1975	215	4	2019;9:11826	2019;9:11826	NUM
ajlm-1975	215	5	.	.	PUNCT
ajlm-1975	216	1	https://doi.org/10.1038/s41598-019-48401-z	https://doi.org/10.1038/s41598-019-48401-z	PROPN
ajlm-1975	216	2	nicd	nicd	PROPN
ajlm-1975	216	3	.	.	PUNCT
ajlm-1975	217	1	microbiologically	microbiologically	ADV
ajlm-1975	217	2	confirmed	confirm	VERB
ajlm-1975	217	3	tuberculosis	tuberculosis	ADP
ajlm-1975	217	4	2004–15	2004–15	NUM
ajlm-1975	217	5	south	south	PROPN
ajlm-1975	217	6	africa	africa	PROPN
ajlm-1975	217	7	.	.	PUNCT
ajlm-1975	218	1	johannesburg	johannesburg	PROPN
ajlm-1975	218	2	:	:	PUNCT
ajlm-1975	218	3	national	national	PROPN
ajlm-1975	218	4	institute	institute	PROPN
ajlm-1975	218	5	for	for	ADP
ajlm-1975	218	6	communicable	communicable	NOUN
ajlm-1975	218	7	diseases	disease	NOUN
ajlm-1975	218	8	;	;	PUNCT
ajlm-1975	218	9	2017	2017	NUM
ajlm-1975	218	10	.	.	PUNCT
ajlm-1975	219	1	lifescience	lifescience	PROPN
ajlm-1975	219	2	h.	h.	PROPN
ajlm-1975	219	3	genotype	genotype	PROPN
ajlm-1975	219	4	mtbdrplus	mtbdrplus	PROPN
ajlm-1975	219	5	ver	ver	PROPN
ajlm-1975	219	6	2.0	2.0	NUM
ajlm-1975	219	7	:	:	PUNCT
ajlm-1975	219	8	molecular	molecular	ADJ
ajlm-1975	219	9	genetic	genetic	ADJ
ajlm-1975	219	10	assay	assay	NOUN
ajlm-1975	219	11	for	for	ADP
ajlm-1975	219	12	identification	identification	NOUN
ajlm-1975	219	13	of	of	ADP
ajlm-1975	219	14	the	the	DET
ajlm-1975	219	15	m.	m.	NOUN
ajlm-1975	219	16	tuberculosis	tuberculosis	NOUN
ajlm-1975	219	17	complex	complex	ADJ
ajlm-1975	219	18	and	and	CCONJ
ajlm-1975	219	19	its	its	PRON
ajlm-1975	219	20	resistance	resistance	NOUN
ajlm-1975	219	21	to	to	ADP
ajlm-1975	219	22	rifampicin	rifampicin	VERB
ajlm-1975	219	23	and	and	CCONJ
ajlm-1975	219	24	isoniazid	isoniazid	NOUN
ajlm-1975	219	25	from	from	ADP
ajlm-1975	219	26	clinical	clinical	ADJ
ajlm-1975	219	27	specimens	specimen	NOUN
ajlm-1975	219	28	and	and	CCONJ
ajlm-1975	219	29	cultivated	cultivate	VERB
ajlm-1975	219	30	samples	sample	NOUN
ajlm-1975	219	31	.	.	PUNCT
ajlm-1975	220	1	2015	2015	NUM
ajlm-1975	220	2	;	;	PUNCT
ajlm-1975	220	3	nehren	nehren	NOUN
ajlm-1975	220	4	,	,	PUNCT
ajlm-1975	220	5	germany	germany	PROPN
ajlm-1975	220	6	:	:	PUNCT
ajlm-1975	220	7	hain	hain	NOUN
ajlm-1975	220	8	lifescience	lifescience	NOUN
ajlm-1975	220	9	.	.	PUNCT
ajlm-1975	221	1	woods	woods	PROPN
ajlm-1975	221	2	gl	gl	PROPN
ajlm-1975	221	3	,	,	PUNCT
ajlm-1975	221	4	brown	brown	PROPN
ajlm-1975	221	5	-	-	PUNCT
ajlm-1975	221	6	elliott	elliott	PROPN
ajlm-1975	221	7	ba	ba	PROPN
ajlm-1975	221	8	,	,	PUNCT
ajlm-1975	221	9	conville	conville	NOUN
ajlm-1975	221	10	ps	ps	PROPN
ajlm-1975	221	11	,	,	PUNCT
ajlm-1975	221	12	et	et	PROPN
ajlm-1975	221	13	al	al	PROPN
ajlm-1975	221	14	.	.	PUNCT
ajlm-1975	221	15	clsi	clsi	PROPN
ajlm-1975	221	16	standards	standard	NOUN
ajlm-1975	221	17	:	:	PUNCT
ajlm-1975	221	18	guidelines	guideline	NOUN
ajlm-1975	221	19	for	for	ADP
ajlm-1975	221	20	health	health	NOUN
ajlm-1975	221	21	care	care	PROPN
ajlm-1975	221	22	excellence	excellence	PROPN
ajlm-1975	221	23	.	.	PUNCT
ajlm-1975	222	1	susceptibility	susceptibility	NOUN
ajlm-1975	222	2	testing	testing	NOUN
ajlm-1975	222	3	of	of	ADP
ajlm-1975	222	4	mycobacteria	mycobacteria	NOUN
ajlm-1975	222	5	,	,	PUNCT
ajlm-1975	222	6	nocardiae	nocardiae	NOUN
ajlm-1975	222	7	,	,	PUNCT
ajlm-1975	222	8	and	and	CCONJ
ajlm-1975	222	9	other	other	ADJ
ajlm-1975	222	10	aerobic	aerobic	ADJ
ajlm-1975	222	11	actinomycetes	actinomycete	NOUN
ajlm-1975	222	12	.	.	PUNCT
ajlm-1975	223	1	wayne	wayne	PROPN
ajlm-1975	223	2	,	,	PUNCT
ajlm-1975	223	3	pa	pa	PROPN
ajlm-1975	223	4	:	:	PUNCT
ajlm-1975	223	5	clinical	clinical	ADJ
ajlm-1975	223	6	and	and	CCONJ
ajlm-1975	223	7	laboratory	laboratory	NOUN
ajlm-1975	223	8	standards	standard	NOUN
ajlm-1975	223	9	institute	institute	NOUN
ajlm-1975	223	10	;	;	PUNCT
ajlm-1975	223	11	2011	2011	NUM
ajlm-1975	223	12	.	.	PUNCT
ajlm-1975	224	1	schleusener	schleusener	NOUN
ajlm-1975	224	2	v	v	PROPN
ajlm-1975	224	3	,	,	PUNCT
ajlm-1975	224	4	köser	köser	PROPN
ajlm-1975	224	5	cu	cu	PROPN
ajlm-1975	224	6	,	,	PUNCT
ajlm-1975	224	7	beckert	beckert	NOUN
ajlm-1975	224	8	p	p	X
ajlm-1975	224	9	,	,	PUNCT
ajlm-1975	224	10	niemann	niemann	PROPN
ajlm-1975	224	11	s	s	PROPN
ajlm-1975	224	12	,	,	PUNCT
ajlm-1975	224	13	feuerriegel	feuerriegel	NOUN
ajlm-1975	224	14	s.	s.	PROPN
ajlm-1975	224	15	mycobacterium	mycobacterium	PROPN
ajlm-1975	224	16	tuberculosis	tuberculosis	NOUN
ajlm-1975	224	17	resistance	resistance	NOUN
ajlm-1975	224	18	prediction	prediction	NOUN
ajlm-1975	224	19	and	and	CCONJ
ajlm-1975	224	20	lineage	lineage	NOUN
ajlm-1975	224	21	classification	classification	NOUN
ajlm-1975	224	22	from	from	ADP
ajlm-1975	224	23	genome	genome	NOUN
ajlm-1975	224	24	sequencing	sequencing	NOUN
ajlm-1975	224	25	:	:	PUNCT
ajlm-1975	224	26	comparison	comparison	NOUN
ajlm-1975	224	27	of	of	ADP
ajlm-1975	224	28	automated	automate	VERB
ajlm-1975	224	29	analysis	analysis	NOUN
ajlm-1975	224	30	tools	tool	NOUN
ajlm-1975	224	31	.	.	PUNCT
ajlm-1975	225	1	sci	sci	PROPN
ajlm-1975	225	2	rep	rep	PROPN
ajlm-1975	225	3	.	.	PROPN
ajlm-1975	225	4	2017;7:46327	2017;7:46327	PROPN
ajlm-1975	225	5	.	.	PUNCT
ajlm-1975	226	1	https://doi.org/10.1038/srep46327	https://doi.org/10.1038/srep46327	PROPN
ajlm-1975	227	1	who	who	PRON
ajlm-1975	227	2	.	.	PUNCT
ajlm-1975	228	1	meeting	meet	VERB
ajlm-1975	228	2	report	report	NOUN
ajlm-1975	228	3	of	of	ADP
ajlm-1975	228	4	the	the	PRON
ajlm-1975	228	5	who	who	PRON
ajlm-1975	228	6	expert	expert	VERB
ajlm-1975	228	7	consultation	consultation	NOUN
ajlm-1975	228	8	on	on	ADP
ajlm-1975	228	9	drug	drug	NOUN
ajlm-1975	228	10	-	-	PUNCT
ajlm-1975	228	11	resistant	resistant	ADJ
ajlm-1975	228	12	tuberculosis	tuberculosis	NOUN
ajlm-1975	228	13	treatment	treatment	NOUN
ajlm-1975	228	14	outcome	outcome	NOUN
ajlm-1975	228	15	definitions	definition	NOUN
ajlm-1975	228	16	,	,	PUNCT
ajlm-1975	228	17	17–19	17–19	NUM
ajlm-1975	228	18	november	november	PROPN
ajlm-1975	228	19	2020	2020	NUM
ajlm-1975	228	20	.	.	PUNCT
ajlm-1975	229	1	geneva	geneva	PROPN
ajlm-1975	229	2	:	:	PUNCT
ajlm-1975	229	3	world	world	PROPN
ajlm-1975	229	4	health	health	NOUN
ajlm-1975	229	5	organization	organization	NOUN
ajlm-1975	229	6	;	;	PUNCT
ajlm-1975	229	7	2021	2021	NUM
ajlm-1975	229	8	.	.	PUNCT
ajlm-1975	230	1	huang	huang	PROPN
ajlm-1975	230	2	wl	wl	PROPN
ajlm-1975	230	3	,	,	PUNCT
ajlm-1975	230	4	chen	chen	PROPN
ajlm-1975	230	5	hy	hy	PROPN
ajlm-1975	230	6	,	,	PUNCT
ajlm-1975	230	7	kuo	kuo	PROPN
ajlm-1975	230	8	ym	ym	PROPN
ajlm-1975	230	9	,	,	PUNCT
ajlm-1975	230	10	jou	jou	PROPN
ajlm-1975	230	11	r.	r.	PROPN
ajlm-1975	230	12	performance	performance	NOUN
ajlm-1975	230	13	assessment	assessment	NOUN
ajlm-1975	230	14	of	of	ADP
ajlm-1975	230	15	the	the	DET
ajlm-1975	230	16	genotype	genotype	NOUN
ajlm-1975	230	17	mtbdrplus	mtbdrplus	ADJ
ajlm-1975	230	18	test	test	NOUN
ajlm-1975	230	19	and	and	CCONJ
ajlm-1975	230	20	dna	dna	NOUN
ajlm-1975	230	21	sequencing	sequence	VERB
ajlm-1975	230	22	in	in	ADP
ajlm-1975	230	23	detection	detection	NOUN
ajlm-1975	230	24	of	of	ADP
ajlm-1975	230	25	multidrug	multidrug	NOUN
ajlm-1975	230	26	-	-	PUNCT
ajlm-1975	230	27	resistant	resistant	ADJ
ajlm-1975	230	28	mycobacterium	mycobacterium	NOUN
ajlm-1975	230	29	tuberculosis	tuberculosis	NOUN
ajlm-1975	230	30	.	.	PUNCT
ajlm-1975	231	1	j	j	PROPN
ajlm-1975	231	2	clin	clin	PROPN
ajlm-1975	231	3	microbiol	microbiol	PROPN
ajlm-1975	231	4	.	.	PUNCT
ajlm-1975	232	1	2009;47(8):2520–2524	2009;47(8):2520–2524	ADJ
ajlm-1975	232	2	.	.	PUNCT
ajlm-1975	233	1	https://doi.org/10.1128/jcm.02499-08	https://doi.org/10.1128/jcm.02499-08	PROPN
ajlm-1975	233	2	köser	köser	PROPN
ajlm-1975	233	3	cu	cu	PROPN
ajlm-1975	233	4	,	,	PUNCT
ajlm-1975	233	5	georghiou	georghiou	PROPN
ajlm-1975	233	6	sb	sb	PROPN
ajlm-1975	233	7	,	,	PUNCT
ajlm-1975	233	8	schön	schön	PROPN
ajlm-1975	233	9	t	t	PROPN
ajlm-1975	233	10	,	,	PUNCT
ajlm-1975	233	11	salfinger	salfinger	NOUN
ajlm-1975	233	12	m.	m.	NOUN
ajlm-1975	233	13	on	on	ADP
ajlm-1975	233	14	the	the	DET
ajlm-1975	233	15	consequences	consequence	NOUN
ajlm-1975	233	16	of	of	ADP
ajlm-1975	233	17	poorly	poorly	ADV
ajlm-1975	233	18	defined	define	VERB
ajlm-1975	233	19	breakpoints	breakpoint	NOUN
ajlm-1975	233	20	for	for	ADP
ajlm-1975	233	21	rifampin	rifampin	NOUN
ajlm-1975	233	22	susceptibility	susceptibility	NOUN
ajlm-1975	233	23	testing	testing	NOUN
ajlm-1975	233	24	of	of	ADP
ajlm-1975	233	25	mycobacterium	mycobacterium	NOUN
ajlm-1975	233	26	tuberculosis	tuberculosis	NOUN
ajlm-1975	233	27	complex	complex	NOUN
ajlm-1975	233	28	.	.	PUNCT
ajlm-1975	234	1	j	j	PROPN
ajlm-1975	234	2	clin	clin	PROPN
ajlm-1975	234	3	microbiol	microbiol	PROPN
ajlm-1975	234	4	.	.	PUNCT
ajlm-1975	235	1	2021;59(4):e02328	2021;59(4):e02328	NUM
ajlm-1975	235	2	-	-	SYM
ajlm-1975	235	3	20	20	NUM
ajlm-1975	235	4	.	.	PUNCT
ajlm-1975	236	1	https://doi.org/10.1128/jcm.02328-20	https://doi.org/10.1128/jcm.02328-20	PROPN
ajlm-1975	236	2	shea	shea	PROPN
ajlm-1975	236	3	j	j	PROPN
ajlm-1975	236	4	,	,	PUNCT
ajlm-1975	236	5	halse	halse	PROPN
ajlm-1975	236	6	ta	ta	PROPN
ajlm-1975	236	7	,	,	PUNCT
ajlm-1975	236	8	kohlerschmidt	kohlerschmidt	PROPN
ajlm-1975	236	9	d	d	X
ajlm-1975	236	10	,	,	PUNCT
ajlm-1975	236	11	et	et	PROPN
ajlm-1975	236	12	al	al	PROPN
ajlm-1975	236	13	.	.	PUNCT
ajlm-1975	236	14	low	low	ADJ
ajlm-1975	236	15	-	-	PUNCT
ajlm-1975	236	16	level	level	NOUN
ajlm-1975	236	17	rifampin	rifampin	NOUN
ajlm-1975	236	18	resistance	resistance	NOUN
ajlm-1975	236	19	and	and	CCONJ
ajlm-1975	236	20	rpob	rpob	ADJ
ajlm-1975	236	21	mutations	mutation	NOUN
ajlm-1975	236	22	in	in	ADP
ajlm-1975	236	23	mycobacterium	mycobacterium	NOUN
ajlm-1975	236	24	tuberculosis	tuberculosis	NOUN
ajlm-1975	236	25	:	:	PUNCT
ajlm-1975	236	26	an	an	DET
ajlm-1975	236	27	analysis	analysis	NOUN
ajlm-1975	236	28	of	of	ADP
ajlm-1975	236	29	whole	whole	ADJ
ajlm-1975	236	30	-	-	PUNCT
ajlm-1975	236	31	genome	genome	NOUN
ajlm-1975	236	32	sequencing	sequencing	NOUN
ajlm-1975	236	33	and	and	CCONJ
ajlm-1975	236	34	drug	drug	NOUN
ajlm-1975	236	35	susceptibility	susceptibility	NOUN
ajlm-1975	236	36	test	test	NOUN
ajlm-1975	236	37	data	datum	NOUN
ajlm-1975	236	38	in	in	ADP
ajlm-1975	236	39	new	new	PROPN
ajlm-1975	236	40	york	york	PROPN
ajlm-1975	236	41	.	.	PUNCT
ajlm-1975	237	1	j	j	PROPN
ajlm-1975	237	2	clin	clin	PROPN
ajlm-1975	237	3	microbiol	microbiol	PROPN
ajlm-1975	237	4	.	.	PUNCT
ajlm-1975	238	1	2021;59	2021;59	NUM
ajlm-1975	238	2	:	:	PUNCT
ajlm-1975	238	3	e01885	e01885	NOUN
ajlm-1975	238	4	-	-	PUNCT
ajlm-1975	238	5	20	20	NUM
ajlm-1975	238	6	.	.	PUNCT
ajlm-1975	239	1	https://doi.org/10.1128/jcm.01885-20	https://doi.org/10.1128/jcm.01885-20	PROPN
ajlm-1975	239	2	manson	manson	PROPN
ajlm-1975	239	3	al	al	PROPN
ajlm-1975	239	4	,	,	PUNCT
ajlm-1975	239	5	cohen	cohen	PROPN
ajlm-1975	239	6	ka	ka	PROPN
ajlm-1975	239	7	,	,	PUNCT
ajlm-1975	239	8	abeel	abeel	PROPN
ajlm-1975	239	9	t	t	PROPN
ajlm-1975	239	10	,	,	PUNCT
ajlm-1975	239	11	desjardins	desjardins	PROPN
ajlm-1975	239	12	ca	can	AUX
ajlm-1975	239	13	,	,	PUNCT
ajlm-1975	239	14	armstrong	armstrong	PROPN
ajlm-1975	239	15	dt	dt	PROPN
ajlm-1975	239	16	,	,	PUNCT
ajlm-1975	239	17	barry	barry	PROPN
ajlm-1975	239	18	ce	ce	PROPN
ajlm-1975	239	19	3rd	3rd	PROPN
ajlm-1975	239	20	,	,	PUNCT
ajlm-1975	239	21	et	et	PROPN
ajlm-1975	239	22	al	al	PROPN
ajlm-1975	239	23	.	.	PUNCT
ajlm-1975	240	1	genomic	genomic	ADJ
ajlm-1975	240	2	analysis	analysis	NOUN
ajlm-1975	240	3	of	of	ADP
ajlm-1975	240	4	globally	globally	ADV
ajlm-1975	240	5	diverse	diverse	ADJ
ajlm-1975	240	6	mycobacterium	mycobacterium	NOUN
ajlm-1975	240	7	tuberculosis	tuberculosis	NOUN
ajlm-1975	240	8	strains	strain	NOUN
ajlm-1975	240	9	provides	provide	VERB
ajlm-1975	240	10	insights	insight	NOUN
ajlm-1975	240	11	into	into	ADP
ajlm-1975	240	12	the	the	DET
ajlm-1975	240	13	emergence	emergence	NOUN
ajlm-1975	240	14	and	and	CCONJ
ajlm-1975	240	15	spread	spread	VERB
ajlm-1975	240	16	of	of	ADP
ajlm-1975	240	17	multidrug	multidrug	NOUN
ajlm-1975	240	18	resistance	resistance	NOUN
ajlm-1975	240	19	.	.	PUNCT
ajlm-1975	241	1	nat	nat	PROPN
ajlm-1975	241	2	genet	genet	PROPN
ajlm-1975	241	3	.	.	PUNCT
ajlm-1975	242	1	2017;49:395–402	2017;49:395–402	X
ajlm-1975	242	2	.	.	PUNCT
ajlm-1975	243	1	https://doi.org/10.1038/ng.3767	https://doi.org/10.1038/ng.3767	PROPN
ajlm-1975	243	2	cohen	cohen	PROPN
ajlm-1975	243	3	ka	ka	PROPN
ajlm-1975	243	4	,	,	PUNCT
ajlm-1975	243	5	abeel	abeel	PROPN
ajlm-1975	243	6	t	t	PROPN
ajlm-1975	243	7	,	,	PUNCT
ajlm-1975	243	8	manson	manson	PROPN
ajlm-1975	243	9	mcguire	mcguire	PROPN
ajlm-1975	243	10	a	a	PROPN
ajlm-1975	243	11	,	,	PUNCT
ajlm-1975	243	12	et	et	PROPN
ajlm-1975	243	13	al	al	PROPN
ajlm-1975	243	14	.	.	PROPN
ajlm-1975	243	15	evolution	evolution	NOUN
ajlm-1975	243	16	of	of	ADP
ajlm-1975	243	17	extensively	extensively	ADV
ajlm-1975	243	18	drug	drug	NOUN
ajlm-1975	243	19	-	-	PUNCT
ajlm-1975	243	20	resistant	resistant	ADJ
ajlm-1975	243	21	tuberculosis	tuberculosis	NOUN
ajlm-1975	243	22	over	over	ADP
ajlm-1975	243	23	four	four	NUM
ajlm-1975	243	24	decades	decade	NOUN
ajlm-1975	243	25	:	:	PUNCT
ajlm-1975	243	26	whole	whole	ADJ
ajlm-1975	243	27	genome	genome	NOUN
ajlm-1975	243	28	sequencing	sequencing	NOUN
ajlm-1975	243	29	and	and	CCONJ
ajlm-1975	243	30	dating	date	VERB
ajlm-1975	243	31	analysis	analysis	NOUN
ajlm-1975	243	32	of	of	ADP
ajlm-1975	243	33	mycobacterium	mycobacterium	NOUN
ajlm-1975	243	34	tuberculosis	tuberculosis	NOUN
ajlm-1975	243	35	isolates	isolate	NOUN
ajlm-1975	243	36	from	from	ADP
ajlm-1975	243	37	kwazulu	kwazulu	NOUN
ajlm-1975	243	38	-	-	PUNCT
ajlm-1975	243	39	natal	natal	NOUN
ajlm-1975	243	40	.	.	PUNCT
ajlm-1975	244	1	plos	plos	PROPN
ajlm-1975	244	2	med	med	PROPN
ajlm-1975	244	3	.	.	PUNCT
ajlm-1975	245	1	2015;12	2015;12	NUM
ajlm-1975	245	2	:	:	PUNCT
ajlm-1975	245	3	e1001880	e1001880	VERB
ajlm-1975	245	4	.	.	PUNCT
ajlm-1975	246	1	https://doi.org/10.1371/journal.pmed.1001880	https://doi.org/10.1371/journal.pmed.1001880	PROPN
ajlm-1975	246	2	gegia	gegia	PROPN
ajlm-1975	246	3	m	m	PROPN
ajlm-1975	246	4	,	,	PUNCT
ajlm-1975	246	5	winters	winter	NOUN
ajlm-1975	246	6	n	n	CCONJ
ajlm-1975	246	7	,	,	PUNCT
ajlm-1975	246	8	benedetti	benedetti	PROPN
ajlm-1975	246	9	a	a	PROPN
ajlm-1975	246	10	,	,	PUNCT
ajlm-1975	246	11	van	van	NOUN
ajlm-1975	246	12	soolingen	soolingen	NOUN
ajlm-1975	246	13	d	d	PROPN
ajlm-1975	246	14	,	,	PUNCT
ajlm-1975	246	15	menzies	menzies	PROPN
ajlm-1975	246	16	d.	d.	PROPN
ajlm-1975	246	17	treatment	treatment	PROPN
ajlm-1975	246	18	of	of	ADP
ajlm-1975	246	19	isoniazid	isoniazid	NOUN
ajlm-1975	246	20	-	-	PUNCT
ajlm-1975	246	21	resistant	resistant	ADJ
ajlm-1975	246	22	tuberculosis	tuberculosis	NOUN
ajlm-1975	246	23	with	with	ADP
ajlm-1975	246	24	first	first	ADJ
ajlm-1975	246	25	-	-	PUNCT
ajlm-1975	246	26	line	line	NOUN
ajlm-1975	246	27	drugs	drug	NOUN
ajlm-1975	246	28	:	:	PUNCT
ajlm-1975	246	29	a	a	DET
ajlm-1975	246	30	systematic	systematic	ADJ
ajlm-1975	246	31	review	review	NOUN
ajlm-1975	246	32	and	and	CCONJ
ajlm-1975	246	33	meta	meta	ADJ
ajlm-1975	246	34	-	-	PUNCT
ajlm-1975	246	35	analysis	analysis	NOUN
ajlm-1975	246	36	.	.	PUNCT
ajlm-1975	247	1	lancet	lancet	PROPN
ajlm-1975	247	2	infect	infect	PROPN
ajlm-1975	247	3	dis	dis	PROPN
ajlm-1975	247	4	.	.	PUNCT
ajlm-1975	248	1	2017;17(2):223–234	2017;17(2):223–234	X
ajlm-1975	248	2	.	.	PUNCT
ajlm-1975	249	1	https://doi.org/10.1016/s1473-3099(16)30407-8	https://doi.org/10.1016/s1473-3099(16)30407-8	PROPN
ajlm-1975	249	2	gandhi	gandhi	PROPN
ajlm-1975	249	3	nr	nr	PROPN
ajlm-1975	249	4	,	,	PUNCT
ajlm-1975	249	5	moll	moll	PROPN
ajlm-1975	249	6	a	a	PROPN
ajlm-1975	249	7	,	,	PUNCT
ajlm-1975	249	8	sturm	sturm	PROPN
ajlm-1975	249	9	aw	aw	INTJ
ajlm-1975	249	10	,	,	PUNCT
ajlm-1975	249	11	et	et	PROPN
ajlm-1975	249	12	al	al	PROPN
ajlm-1975	249	13	.	.	PUNCT
ajlm-1975	250	1	extensively	extensively	ADV
ajlm-1975	250	2	drug	drug	NOUN
ajlm-1975	250	3	-	-	PUNCT
ajlm-1975	250	4	resistant	resistant	ADJ
ajlm-1975	250	5	tuberculosis	tuberculosis	NOUN
ajlm-1975	250	6	as	as	ADP
ajlm-1975	250	7	a	a	DET
ajlm-1975	250	8	cause	cause	NOUN
ajlm-1975	250	9	of	of	ADP
ajlm-1975	250	10	death	death	NOUN
ajlm-1975	250	11	in	in	ADP
ajlm-1975	250	12	patients	patient	NOUN
ajlm-1975	250	13	co	co	VERB
ajlm-1975	250	14	-	-	VERB
ajlm-1975	250	15	infected	infected	ADJ
ajlm-1975	250	16	with	with	ADP
ajlm-1975	250	17	tuberculosis	tuberculosis	NOUN
ajlm-1975	250	18	and	and	CCONJ
ajlm-1975	250	19	hiv	hiv	PROPN
ajlm-1975	250	20	in	in	ADP
ajlm-1975	250	21	a	a	DET
ajlm-1975	250	22	rural	rural	ADJ
ajlm-1975	250	23	area	area	NOUN
ajlm-1975	250	24	of	of	ADP
ajlm-1975	250	25	south	south	PROPN
ajlm-1975	250	26	africa	africa	PROPN
ajlm-1975	250	27	.	.	PUNCT
ajlm-1975	251	1	lancet	lancet	PROPN
ajlm-1975	251	2	.	.	PUNCT
ajlm-1975	252	1	2006;368(9547):1575–1580	2006;368(9547):1575–1580	NOUN
ajlm-1975	252	2	.	.	PUNCT
ajlm-1975	253	1	https://doi.org/10.1016/s0140-6736(06)69573-1	https://doi.org/10.1016/s0140-6736(06)69573-1	PROPN
ajlm-1975	253	2	pillay	pillay	PROPN
ajlm-1975	253	3	m	m	PROPN
ajlm-1975	253	4	,	,	PUNCT
ajlm-1975	253	5	sturm	sturm	PROPN
ajlm-1975	253	6	aw	aw	INTJ
ajlm-1975	253	7	.	.	PROPN
ajlm-1975	253	8	evolution	evolution	NOUN
ajlm-1975	253	9	of	of	ADP
ajlm-1975	253	10	the	the	DET
ajlm-1975	253	11	extensively	extensively	ADV
ajlm-1975	253	12	drug	drug	NOUN
ajlm-1975	253	13	-	-	PUNCT
ajlm-1975	253	14	resistant	resistant	ADJ
ajlm-1975	253	15	f15	f15	PROPN
ajlm-1975	253	16	/	/	SYM
ajlm-1975	253	17	lam4	lam4	PROPN
ajlm-1975	253	18	/	/	SYM
ajlm-1975	253	19	kzn	kzn	PROPN
ajlm-1975	253	20	strain	strain	NOUN
ajlm-1975	253	21	of	of	ADP
ajlm-1975	253	22	mycobacterium	mycobacterium	NOUN
ajlm-1975	253	23	tuberculosis	tuberculosis	NOUN
ajlm-1975	253	24	in	in	ADP
ajlm-1975	253	25	kwazulu	kwazulu	NOUN
ajlm-1975	253	26	-	-	PUNCT
ajlm-1975	253	27	natal	natal	ADJ
ajlm-1975	253	28	,	,	PUNCT
ajlm-1975	253	29	south	south	PROPN
ajlm-1975	253	30	africa	africa	PROPN
ajlm-1975	253	31	.	.	PUNCT
ajlm-1975	254	1	clin	clin	PROPN
ajlm-1975	254	2	infect	infect	PROPN
ajlm-1975	254	3	dis	dis	PROPN
ajlm-1975	254	4	.	.	PUNCT
ajlm-1975	255	1	2007;45:1409–1414	2007;45:1409–1414	NUM
ajlm-1975	255	2	.	.	PUNCT
ajlm-1975	256	1	https://doi.org/10.1086/522987	https://doi.org/10.1086/522987	NUM
ajlm-1975	256	2	who	who	PRON
ajlm-1975	256	3	.	.	PUNCT
ajlm-1975	257	1	the	the	DET
ajlm-1975	257	2	use	use	NOUN
ajlm-1975	257	3	of	of	ADP
ajlm-1975	257	4	next	next	ADJ
ajlm-1975	257	5	-	-	PUNCT
ajlm-1975	257	6	generation	generation	NOUN
ajlm-1975	257	7	sequencing	sequencing	NOUN
ajlm-1975	257	8	technologies	technology	NOUN
ajlm-1975	257	9	for	for	ADP
ajlm-1975	257	10	the	the	DET
ajlm-1975	257	11	detection	detection	NOUN
ajlm-1975	257	12	of	of	ADP
ajlm-1975	257	13	mutations	mutation	NOUN
ajlm-1975	257	14	associated	associate	VERB
ajlm-1975	257	15	with	with	ADP
ajlm-1975	257	16	drug	drug	NOUN
ajlm-1975	257	17	resistance	resistance	NOUN
ajlm-1975	257	18	in	in	ADP
ajlm-1975	257	19	mycobacterium	mycobacterium	NOUN
ajlm-1975	257	20	tuberculosis	tuberculosis	NOUN
ajlm-1975	257	21	complex	complex	NOUN
ajlm-1975	257	22	:	:	PUNCT
ajlm-1975	257	23	technical	technical	ADJ
ajlm-1975	257	24	guide	guide	NOUN
ajlm-1975	257	25	.	.	PUNCT
ajlm-1975	258	1	geneva	geneva	PROPN
ajlm-1975	258	2	:	:	PUNCT
ajlm-1975	258	3	world	world	PROPN
ajlm-1975	258	4	health	health	NOUN
ajlm-1975	258	5	organization	organization	NOUN
ajlm-1975	258	6	;	;	PUNCT
ajlm-1975	258	7	2018	2018	NUM
ajlm-1975	258	8	.	.	PUNCT
ajlm-1975	259	1	schön	schön	PROPN
ajlm-1975	259	2	t	t	PROPN
ajlm-1975	259	3	,	,	PUNCT
ajlm-1975	259	4	juréen	juréen	PROPN
ajlm-1975	259	5	p	p	NOUN
ajlm-1975	259	6	,	,	PUNCT
ajlm-1975	259	7	giske	giske	PROPN
ajlm-1975	259	8	cg	cg	PROPN
ajlm-1975	259	9	,	,	PUNCT
ajlm-1975	259	10	et	et	PROPN
ajlm-1975	259	11	al	al	PROPN
ajlm-1975	259	12	.	.	PUNCT
ajlm-1975	259	13	evaluation	evaluation	NOUN
ajlm-1975	259	14	of	of	ADP
ajlm-1975	259	15	wild	wild	ADJ
ajlm-1975	259	16	-	-	PUNCT
ajlm-1975	259	17	type	type	NOUN
ajlm-1975	259	18	mic	mic	ADJ
ajlm-1975	259	19	distributions	distribution	NOUN
ajlm-1975	259	20	as	as	ADP
ajlm-1975	259	21	a	a	DET
ajlm-1975	259	22	tool	tool	NOUN
ajlm-1975	259	23	for	for	ADP
ajlm-1975	259	24	determination	determination	NOUN
ajlm-1975	259	25	of	of	ADP
ajlm-1975	259	26	clinical	clinical	ADJ
ajlm-1975	259	27	breakpoints	breakpoint	NOUN
ajlm-1975	259	28	for	for	ADP
ajlm-1975	259	29	mycobacterium	mycobacterium	NOUN
ajlm-1975	259	30	tuberculosis	tuberculosis	NOUN
ajlm-1975	259	31	.	.	PUNCT
ajlm-1975	260	1	j	j	PROPN
ajlm-1975	260	2	antimicrob	antimicrob	PROPN
ajlm-1975	260	3	chemother	chemother	PROPN
ajlm-1975	260	4	.	.	PUNCT
ajlm-1975	261	1	2009;64(4):786–793	2009;64(4):786–793	X
ajlm-1975	261	2	.	.	PUNCT
ajlm-1975	262	1	https://doi.org/10.1093/jac/dkp262	https://doi.org/10.1093/jac/dkp262	NOUN
ajlm-1975	262	2	zhang	zhang	PROPN
ajlm-1975	262	3	y	y	PROPN
ajlm-1975	262	4	,	,	PUNCT
ajlm-1975	262	5	permar	permar	PROPN
ajlm-1975	262	6	s	s	PROPN
ajlm-1975	262	7	,	,	PUNCT
ajlm-1975	262	8	sun	sun	PROPN
ajlm-1975	262	9	z.	z.	PROPN
ajlm-1975	262	10	conditions	condition	NOUN
ajlm-1975	262	11	that	that	PRON
ajlm-1975	262	12	may	may	AUX
ajlm-1975	262	13	affect	affect	VERB
ajlm-1975	262	14	the	the	DET
ajlm-1975	262	15	results	result	NOUN
ajlm-1975	262	16	of	of	ADP
ajlm-1975	262	17	susceptibility	susceptibility	NOUN
ajlm-1975	262	18	testing	testing	NOUN
ajlm-1975	262	19	of	of	ADP
ajlm-1975	262	20	mycobacterium	mycobacterium	NOUN
ajlm-1975	262	21	tuberculosis	tuberculosis	NOUN
ajlm-1975	262	22	to	to	PART
ajlm-1975	262	23	pyrazinamide	pyrazinamide	VERB
ajlm-1975	262	24	.	.	PUNCT
ajlm-1975	263	1	j	j	PROPN
ajlm-1975	263	2	med	med	PROPN
ajlm-1975	263	3	microbiol	microbiol	PROPN
ajlm-1975	263	4	.	.	PUNCT
ajlm-1975	264	1	2002;51(1):42–49	2002;51(1):42–49	X
ajlm-1975	264	2	.	.	PUNCT
ajlm-1975	265	1	https://doi.org/10.1099/0022-1317-51-1-42	https://doi.org/10.1099/0022-1317-51-1-42	PROPN
ajlm-1975	265	2	werngren	werngren	PROPN
ajlm-1975	265	3	j	j	PROPN
ajlm-1975	265	4	,	,	PUNCT
ajlm-1975	265	5	sturegård	sturegård	PROPN
ajlm-1975	265	6	e	e	PROPN
ajlm-1975	265	7	,	,	PUNCT
ajlm-1975	265	8	juréen	juréen	NOUN
ajlm-1975	265	9	p	p	NOUN
ajlm-1975	265	10	,	,	PUNCT
ajlm-1975	265	11	ängeby	ängeby	ADV
ajlm-1975	265	12	k	k	NOUN
ajlm-1975	265	13	,	,	PUNCT
ajlm-1975	265	14	hoffner	hoffner	ADP
ajlm-1975	265	15	s	s	PROPN
ajlm-1975	265	16	,	,	PUNCT
ajlm-1975	265	17	schön	schön	PROPN
ajlm-1975	265	18	t.	t.	PROPN
ajlm-1975	265	19	reevaluation	reevaluation	NOUN
ajlm-1975	265	20	of	of	ADP
ajlm-1975	265	21	the	the	DET
ajlm-1975	265	22	critical	critical	ADJ
ajlm-1975	265	23	concentration	concentration	NOUN
ajlm-1975	265	24	for	for	ADP
ajlm-1975	265	25	drug	drug	NOUN
ajlm-1975	265	26	susceptibility	susceptibility	NOUN
ajlm-1975	265	27	testing	testing	NOUN
ajlm-1975	265	28	of	of	ADP
ajlm-1975	265	29	mycobacterium	mycobacterium	NOUN
ajlm-1975	265	30	tuberculosis	tuberculosis	NOUN
ajlm-1975	265	31	against	against	ADP
ajlm-1975	265	32	pyrazinamide	pyrazinamide	NOUN
ajlm-1975	265	33	using	use	VERB
ajlm-1975	265	34	wild	wild	ADJ
ajlm-1975	265	35	-	-	PUNCT
ajlm-1975	265	36	type	type	NOUN
ajlm-1975	265	37	mic	mic	ADJ
ajlm-1975	265	38	distributions	distribution	NOUN
ajlm-1975	265	39	and	and	CCONJ
ajlm-1975	265	40	pnca	pnca	PROPN
ajlm-1975	265	41	gene	gene	NOUN
ajlm-1975	265	42	sequencing	sequence	VERB
ajlm-1975	265	43	.	.	PUNCT
ajlm-1975	266	1	antimicrob	antimicrob	PROPN
ajlm-1975	266	2	agents	agents	PROPN
ajlm-1975	266	3	chemother	chemother	PROPN
ajlm-1975	266	4	.	.	PUNCT
ajlm-1975	267	1	2012;56(3):1253–1257	2012;56(3):1253–1257	NOUN
ajlm-1975	267	2	.	.	PUNCT
ajlm-1975	268	1	https://doi.org/10.1128/aac.05894-11	https://doi.org/10.1128/aac.05894-11	PROPN
ajlm-1975	268	2	gandhi	gandhi	PROPN
ajlm-1975	268	3	nr	nr	PROPN
ajlm-1975	268	4	,	,	PUNCT
ajlm-1975	268	5	brust	brust	PROPN
ajlm-1975	268	6	jcm	jcm	PROPN
ajlm-1975	268	7	,	,	PUNCT
ajlm-1975	268	8	moodley	moodley	NOUN
ajlm-1975	268	9	p	p	NOUN
ajlm-1975	268	10	,	,	PUNCT
ajlm-1975	268	11	et	et	PROPN
ajlm-1975	268	12	al	al	PROPN
ajlm-1975	268	13	.	.	PROPN
ajlm-1975	268	14	minimal	minimal	ADJ
ajlm-1975	268	15	diversity	diversity	NOUN
ajlm-1975	268	16	of	of	ADP
ajlm-1975	268	17	drug	drug	NOUN
ajlm-1975	268	18	-	-	PUNCT
ajlm-1975	268	19	resistant	resistant	ADJ
ajlm-1975	268	20	mycobacterium	mycobacterium	NOUN
ajlm-1975	268	21	tuberculosis	tuberculosis	NOUN
ajlm-1975	268	22	strains	strain	NOUN
ajlm-1975	268	23	,	,	PUNCT
ajlm-1975	268	24	south	south	PROPN
ajlm-1975	268	25	africa	africa	PROPN
ajlm-1975	268	26	.	.	PUNCT
ajlm-1975	269	1	emerg	emerg	PROPN
ajlm-1975	269	2	infect	infect	PROPN
ajlm-1975	269	3	dis	dis	PROPN
ajlm-1975	269	4	.	.	PUNCT
ajlm-1975	270	1	2014;20(3):426–433	2014;20(3):426–433	NUM
ajlm-1975	270	2	.	.	PUNCT
ajlm-1975	270	3	https://doi.org/10.3201/eid2003.131083	https://doi.org/10.3201/eid2003.131083	PUNCT