id	sid	eid	entity	type
aisthesis-3151	1	1	1	CARDINAL
aisthesis-3151	2	1	nearly 23%	PERCENT
aisthesis-3151	2	2	approximately 21%	PERCENT
aisthesis-3151	2	3	approximately 18%	PERCENT
aisthesis-3151	2	4	nearly 18%	PERCENT
aisthesis-3151	3	1	2018	DATE
aisthesis-3151	3	2	american	NORP
aisthesis-3151	3	3	2018	DATE
aisthesis-3151	6	1	von	PRODUCT
aisthesis-3151	6	2	malignancy.%a&er	PRODUCT
aisthesis-3151	8	1	three	CARDINAL
aisthesis-3151	8	2	the 1990s	DATE
aisthesis-3151	8	3	vegf-tkis	ORG
aisthesis-3151	8	4	the 2000s	DATE
aisthesis-3151	10	1	11	CARDINAL
aisthesis-3151	10	2	20201	DATE
aisthesis-3151	11	1	nityam rathi introduction renal cell carcinoma	ORG
aisthesis-3151	12	1	more than 140,000	CARDINAL
aisthesis-3151	12	2	yearly	DATE
aisthesis-3151	12	3	capitanio et al.	PERSON
aisthesis-3151	12	4	2019	DATE
aisthesis-3151	13	1	1	CARDINAL
aisthesis-3151	13	2	american	NORP
aisthesis-3151	13	3	2018	DATE
aisthesis-3151	16	1	bianchi et al.	PERSON
aisthesis-3151	16	2	2012	DATE
aisthesis-3151	17	1	the last 30 years	DATE
aisthesis-3151	20	1	11	CARDINAL
aisthesis-3151	20	2	20202	DATE
aisthesis-3151	20	3	age 37	DATE
aisthesis-3151	20	4	age 61	DATE
aisthesis-3151	20	5	2003	DATE
aisthesis-3151	21	1	von	PRODUCT
aisthesis-3151	21	2	1993	DATE
aisthesis-3151	27	1	three	CARDINAL
aisthesis-3151	27	2	the 1990s	DATE
aisthesis-3151	27	3	vegf-tkis	ORG
aisthesis-3151	27	4	the 2000s	DATE
aisthesis-3151	30	1	between 1900 and 1987	DATE
aisthesis-3151	30	2	1989	DATE
aisthesis-3151	36	1	the early 1990s	DATE
aisthesis-3151	37	1	two	CARDINAL
aisthesis-3151	37	2	2	CARDINAL
aisthesis-3151	38	1	two	CARDINAL
aisthesis-3151	40	1	1987	DATE
aisthesis-3151	41	1	atkins et al.	PERSON
aisthesis-3151	41	2	1993	DATE
aisthesis-3151	42	1	atkins et al	PERSON
aisthesis-3151	43	1	1993	DATE
aisthesis-3151	44	1	atkins et al	PERSON
aisthesis-3151	44	2	99	CARDINAL
aisthesis-3151	45	1	28	CARDINAL
aisthesis-3151	45	2	71	CARDINAL
aisthesis-3151	45	3	hdil2	ORG
aisthesis-3151	46	1	26 months	DATE
aisthesis-3151	47	1	2	CARDINAL
aisthesis-3151	47	2	15.5 months	DATE
aisthesis-3151	47	3	16 months	DATE
aisthesis-3151	47	4	hdil2	ORG
aisthesis-3151	47	5	17%	PERCENT
aisthesis-3151	47	6	11%	PERCENT
aisthesis-3151	50	1	2	CARDINAL
aisthesis-3151	51	1	every 8 hours	TIME
aisthesis-3151	51	2	1 to 5	CARDINAL
aisthesis-3151	51	3	0.8 mg/m2	QUANTITY
aisthesis-3151	51	4	3	CARDINAL
aisthesis-3151	51	5	1.33 mg/m2	QUANTITY
aisthesis-3151	53	1	24 months	DATE
aisthesis-3151	53	2	approximately 70%	PERCENT
aisthesis-3151	55	1	24 months	DATE
aisthesis-3151	55	2	approximately 70%	PERCENT
aisthesis-3151	56	1	atkins et al.	PERSON
aisthesis-3151	56	2	1993	DATE
aisthesis-3151	57	1	11	CARDINAL
aisthesis-3151	57	2	20203	DATE
aisthesis-3151	57	3	fyfe et al.	PERSON
aisthesis-3151	57	4	1995	DATE
aisthesis-3151	58	1	atkins et al	PERSON
aisthesis-3151	58	2	bene$t	ORG
aisthesis-3151	60	1	two	CARDINAL
aisthesis-3151	62	1	fda	ORG
aisthesis-3151	62	2	1992	DATE
aisthesis-3151	63	1	2003	DATE
aisthesis-3151	64	1	vegf	PERSON
aisthesis-3151	67	1	three	CARDINAL
aisthesis-3151	68	1	one	CARDINAL
aisthesis-3151	68	2	three	CARDINAL
aisthesis-3151	68	3	morabito et al	PERSON
aisthesis-3151	68	4	2006	DATE
aisthesis-3151	70	1	vegf-tkis	PERSON
aisthesis-3151	70	2	3	CARDINAL
aisthesis-3151	70	3	di"erent vegf-tki	ORG
aisthesis-3151	71	1	vegf-tkis	ORG
aisthesis-3151	73	1	sunitinib	PERSON
aisthesis-3151	73	2	mek	ORG
aisthesis-3151	74	1	morabito et al.	PERSON
aisthesis-3151	74	2	2006	DATE
aisthesis-3151	75	1	4	CARDINAL
aisthesis-3151	75	2	750	CARDINAL
aisthesis-3151	75	3	1:1	CARDINAL
aisthesis-3151	76	1	sunitinib	PERSON
aisthesis-3151	76	2	50	CARDINAL
aisthesis-3151	76	3	daily	DATE
aisthesis-3151	76	4	6-week	DATE
aisthesis-3151	76	5	4 weeks	DATE
aisthesis-3151	76	6	2 weeks	DATE
aisthesis-3151	77	1	three	CARDINAL
aisthesis-3151	77	2	3 mu	QUANTITY
aisthesis-3151	77	3	$rst week	DATE
aisthesis-3151	77	4	6 mu	QUANTITY
aisthesis-3151	77	5	the second week	DATE
aisthesis-3151	77	6	9 mu	QUANTITY
aisthesis-3151	78	1	pfs	PERSON
aisthesis-3151	78	2	approximately 11 months	DATE
aisthesis-3151	78	3	approximately 5 months	DATE
aisthesis-3151	78	4	2007	DATE
aisthesis-3151	79	1	11	CARDINAL
aisthesis-3151	79	2	20204	DATE
aisthesis-3151	80	1	3	CARDINAL
aisthesis-3151	81	1	xenogra& models	ORG
aisthesis-3151	81	2	mendel et al.	PERSON
aisthesis-3151	81	3	2003	DATE
aisthesis-3151	84	1	2007	DATE
aisthesis-3151	86	1	750	CARDINAL
aisthesis-3151	86	2	1:1	CARDINAL
aisthesis-3151	88	1	11 months	DATE
aisthesis-3151	88	2	5 months	DATE
aisthesis-3151	88	3	4	CARDINAL
aisthesis-3151	89	1	13%	PERCENT
aisthesis-3151	89	2	8%	PERCENT
aisthesis-3151	91	1	6.4%	PERCENT
aisthesis-3151	91	2	0.3%	PERCENT
aisthesis-3151	91	3	14.1%	PERCENT
aisthesis-3151	91	4	3.3%	PERCENT
aisthesis-3151	92	1	2008	DATE
aisthesis-3151	92	2	2018	DATE
aisthesis-3151	96	1	5	CARDINAL
aisthesis-3151	96	2	nivolumab	PERSON
aisthesis-3151	98	1	1	CARDINAL
aisthesis-3151	98	2	a(nity	PRODUCT
aisthesis-3151	98	3	2017	DATE
aisthesis-3151	99	1	cd28	ORG
aisthesis-3151	100	1	second	ORDINAL
aisthesis-3151	101	1	ipilimumab	PERSON
aisthesis-3151	102	1	lipson & drake	ORG
aisthesis-3151	102	2	2011	DATE
aisthesis-3151	103	1	11	CARDINAL
aisthesis-3151	103	2	20205	DATE
aisthesis-3151	105	1	vegf-tkis	ORG
aisthesis-3151	107	1	pathwayspeci$c	GPE
aisthesis-3151	108	1	2009	CARDINAL
aisthesis-3151	109	1	2004	DATE
aisthesis-3151	109	2	takahashi et al.	PERSON
aisthesis-3151	109	3	2004	DATE
aisthesis-3151	110	1	1	CARDINAL
aisthesis-3151	110	2	#	CARDINAL
aisthesis-3151	110	3	al.	GPE
aisthesis-3151	110	4	2006	DATE
aisthesis-3151	112	1	two	CARDINAL
aisthesis-3151	112	2	pdl1	NORP
aisthesis-3151	113	1	2009	DATE
aisthesis-3151	113	2	two	CARDINAL
aisthesis-3151	114	1	#e $	MONEY
aisthesis-3151	115	1	second	ORDINAL
aisthesis-3151	116	1	5	CARDINAL
aisthesis-3151	117	1	mcdermott et al.	PERSON
aisthesis-3151	117	2	2015	DATE
aisthesis-3151	118	1	10.0 months	DATE
aisthesis-3151	118	2	6.4 months	DATE
aisthesis-3151	118	3	2010	DATE
aisthesis-3151	119	1	two	CARDINAL
aisthesis-3151	119	2	melero et al.	GPE
aisthesis-3151	119	3	2015	DATE
aisthesis-3151	120	1	0214	DATE
aisthesis-3151	120	2	approximately 850	CARDINAL
aisthesis-3151	120	3	6	CARDINAL
aisthesis-3151	121	1	12 months	DATE
aisthesis-3151	125	1	2018	DATE
aisthesis-3151	126	1	11	CARDINAL
aisthesis-3151	126	2	20206	DATE
aisthesis-3151	126	3	one	CARDINAL
aisthesis-3151	126	4	two	CARDINAL
aisthesis-3151	126	5	425	CARDINAL
aisthesis-3151	126	6	422	CARDINAL
aisthesis-3151	126	7	motzer et al.	PERSON
aisthesis-3151	126	8	2018	DATE
aisthesis-3151	128	1	6	CARDINAL
aisthesis-3151	129	1	26.0 months	DATE
aisthesis-3151	129	2	11.6 months	DATE
aisthesis-3151	129	3	8.4 months	DATE
aisthesis-3151	131	1	#ese $	MONEY
aisthesis-3151	134	1	vegf-tkis	PERSON
aisthesis-3151	134	2	vegf-tkis	ORG
aisthesis-3151	134	3	2018	DATE
aisthesis-3151	135	1	zhu et al.	PERSON
aisthesis-3151	135	2	2019	DATE
aisthesis-3151	136	1	the last thirty years	DATE
aisthesis-3151	139	1	hdil2	ORG
aisthesis-3151	140	1	the early 2000s	DATE
aisthesis-3151	142	1	11	CARDINAL
aisthesis-3151	142	2	2020	DATE
aisthesis-3151	143	1	fda	ORG
aisthesis-3151	143	2	vegf-tkis	ORG
aisthesis-3151	144	1	the late 2000s	DATE
aisthesis-3151	145	1	the pd-1/pd-l1	EVENT
aisthesis-3151	146	1	0214	DATE
aisthesis-3151	146	2	vegf-tkis	ORG
aisthesis-3151	151	1	american	NORP
aisthesis-3151	152	1	2018	DATE
aisthesis-3151	152	2	april 27	DATE
aisthesis-3151	153	1	2018	DATE
aisthesis-3151	155	1	m. b.	PERSON
aisthesis-3151	155	2	j., fisher	ORG
aisthesis-3151	155	3	r. i.	PERSON
aisthesis-3151	155	4	weiss	ORG
aisthesis-3151	155	5	g. r.	PERSON
aisthesis-3151	155	6	margolin	GPE
aisthesis-3151	155	7	k. a.	PERSON
aisthesis-3151	155	8	fink	ORG
aisthesis-3151	155	9	k.	PERSON
aisthesis-3151	157	1	1993	DATE
aisthesis-3151	159	1	11(4	DATE
aisthesis-3151	159	2	661	CARDINAL
aisthesis-3151	160	1	bianchi	PERSON
aisthesis-3151	160	2	sun	PERSON
aisthesis-3151	160	3	jeldres	GPE
aisthesis-3151	160	4	c.	GPE
aisthesis-3151	160	5	shariat	GPE
aisthesis-3151	160	6	s. f.	PERSON
aisthesis-3151	160	7	trinh	ORG
aisthesis-3151	160	8	q. d.	PERSON
aisthesis-3151	160	9	briganti, a. .	ORG
aisthesis-3151	161	1	karakiewicz	PERSON
aisthesis-3151	161	2	p. i.	PERSON
aisthesis-3151	161	3	2012	DATE
aisthesis-3151	163	1	23(4	CARDINAL
aisthesis-3151	163	2	973	CARDINAL
aisthesis-3151	164	1	brunda	PERSON
aisthesis-3151	164	2	m. j.	PERSON
aisthesis-3151	164	3	d., & sulich	ORG
aisthesis-3151	164	4	1987	DATE
aisthesis-3151	167	1	40(3	CARDINAL
aisthesis-3151	167	2	365-371	CARDINAL
aisthesis-3151	168	1	capitanio	GPE
aisthesis-3151	168	2	k.	PERSON
aisthesis-3151	168	3	bex, a.	PERSON
aisthesis-3151	168	4	boorjian	NORP
aisthesis-3151	168	5	s.	GPE
aisthesis-3151	168	6	bray	ORG
aisthesis-3151	168	7	f.	PERSON
aisthesis-3151	168	8	j.	PERSON
aisthesis-3151	169	1	russo	PERSON
aisthesis-3151	169	2	2019	DATE
aisthesis-3151	171	1	european	NORP
aisthesis-3151	171	2	74-84	CARDINAL
aisthesis-3151	172	1	catino	GPE
aisthesis-3151	172	2	a. b.	PERSON
aisthesis-3151	172	3	hubbard	GPE
aisthesis-3151	172	4	r. a.	PERSON
aisthesis-3151	172	5	chirinos	ORG
aisthesis-3151	172	6	j. c.	PERSON
aisthesis-3151	172	7	townsend	GPE
aisthesis-3151	172	8	r. m.	PERSON
aisthesis-3151	172	9	keefe, s.	PERSON
aisthesis-3151	172	10	haas, n.	ORG
aisthesis-3151	173	1	2018	DATE
aisthesis-3151	175	1	11(3	CARDINAL
aisthesis-3151	175	2	1990	DATE
aisthesis-3151	177	1	1900 to 1987	DATE
aisthesis-3151	178	1	acta oncologica	PERSON
aisthesis-3151	178	2	stockholm	GPE
aisthesis-3151	178	3	sweden	GPE
aisthesis-3151	178	4	29(5	CARDINAL
aisthesis-3151	178	5	545-550	CARDINAL
aisthesis-3151	179	1	fyfe	PERSON
aisthesis-3151	179	2	g.	PERSON
aisthesis-3151	179	3	fisher	ORG
aisthesis-3151	179	4	r. i.	PERSON
aisthesis-3151	179	5	rosenburg	GPE
aisthesis-3151	179	6	s. a.	PERSON
aisthesis-3151	179	7	sznol	GPE
aisthesis-3151	179	8	m.	PERSON
aisthesis-3151	179	9	d. r.	NORP
aisthesis-3151	179	10	a. c.	PERSON
aisthesis-3151	179	11	1995	DATE
aisthesis-3151	180	1	255	CARDINAL
aisthesis-3151	181	1	13(3	CARDINAL
aisthesis-3151	181	2	688	CARDINAL
aisthesis-3151	182	1	f.	PERSON
aisthesis-3151	182	2	o’day	DATE
aisthesis-3151	182	3	s.	PERSON
aisthesis-3151	182	4	mcdermott	PERSON
aisthesis-3151	182	5	d.	NORP
aisthesis-3151	182	6	weber	GPE
aisthesis-3151	182	7	r.	NORP
aisthesis-3151	182	8	j., haanen	ORG
aisthesis-3151	182	9	j.	PERSON
aisthesis-3151	183	1	lebbé	PERSON
aisthesis-3151	183	2	2010	DATE
aisthesis-3151	185	1	e new england journal of medicine	ORG
aisthesis-3151	185	2	363(8	CARDINAL
aisthesis-3151	185	3	711	CARDINAL
aisthesis-3151	186	1	tory	NORP
aisthesis-3151	186	2	k.	PERSON
aisthesis-3151	186	3	j.	PERSON
aisthesis-3151	186	4	m.	PERSON
aisthesis-3151	186	5	f. m.	PERSON
aisthesis-3151	186	6	orcutt	ORG
aisthesis-3151	186	7	m. l	PERSON
aisthesis-3151	187	1	lerman	PERSON
aisthesis-3151	187	2	m. i.	PERSON
aisthesis-3151	187	3	1993	DATE
aisthesis-3151	188	1	von	PRODUCT
aisthesis-3151	189	1	260(5112	CARDINAL
aisthesis-3151	189	2	1317-1320	CARDINAL
aisthesis-3151	190	1	mcdermott	PERSON
aisthesis-3151	190	2	d.	NORP
aisthesis-3151	190	3	drake	PERSON
aisthesis-3151	190	4	c.	PERSON
aisthesis-3151	190	5	sznol	GPE
aisthesis-3151	190	6	m.	PERSON
aisthesis-3151	190	7	t.	GPE
aisthesis-3151	190	8	j., smith	ORG
aisthesis-3151	190	9	d.	NORP
aisthesis-3151	191	1	atkins	PERSON
aisthesis-3151	191	2	2015	DATE
aisthesis-3151	193	1	2013-20	DATE
aisthesis-3151	193	2	7	CARDINAL
aisthesis-3151	194	1	11	CARDINAL
aisthesis-3151	194	2	2020	DATE
aisthesis-3151	194	3	i.	GPE
aisthesis-3151	194	4	berman	PERSON
aisthesis-3151	194	5	d., aznar	PERSON
aisthesis-3151	194	6	gracia	PERSON
aisthesis-3151	194	7	j., & haanen	ORG
aisthesis-3151	194	8	j. (	PERSON
aisthesis-3151	194	9	2015	CARDINAL
aisthesis-3151	196	1	457	CARDINAL
aisthesis-3151	197	1	mendel	ORG
aisthesis-3151	197	2	d.	NORP
aisthesis-3151	197	3	laird	PERSON
aisthesis-3151	197	4	x.	GPE
aisthesis-3151	197	5	louie	PERSON
aisthesis-3151	197	6	s.	PERSON
aisthesis-3151	197	7	christensen	PERSON
aisthesis-3151	197	8	j., li	PERSON
aisthesis-3151	197	9	g.	PERSON
aisthesis-3151	198	1	cherrington	PERSON
aisthesis-3151	198	2	j. (	GPE
aisthesis-3151	198	3	2003	DATE
aisthesis-3151	199	1	su11248	ORG
aisthesis-3151	200	1	the american association	ORG
aisthesis-3151	200	2	9(1	CARDINAL
aisthesis-3151	200	3	327-337	CARDINAL
aisthesis-3151	201	1	morabito, a., de maio	ORG
aisthesis-3151	201	2	e., di maio	GPE
aisthesis-3151	201	3	m.	PERSON
aisthesis-3151	201	4	n., & perrone, f. (2006	ORG
aisthesis-3151	203	1	11(7	CARDINAL
aisthesis-3151	203	2	753	CARDINAL
aisthesis-3151	204	1	motzer	PERSON
aisthesis-3151	204	2	r.	NORP
aisthesis-3151	204	3	hutson	GPE
aisthesis-3151	204	4	t.	GPE
aisthesis-3151	204	5	michaelson	PERSON
aisthesis-3151	204	6	bukowski	PERSON
aisthesis-3151	204	7	r.	NORP
aisthesis-3151	206	1	figlin	PERSON
aisthesis-3151	206	2	r.	NORP
aisthesis-3151	206	3	2007	DATE
aisthesis-3151	207	1	sunitinib versus	PERSON
aisthesis-3151	208	1	e new england journal of medicine	ORG
aisthesis-3151	208	2	356(2	CARDINAL
aisthesis-3151	208	3	115	CARDINAL
aisthesis-3151	209	1	motzer	PERSON
aisthesis-3151	209	2	r.	NORP
aisthesis-3151	209	3	n.	PERSON
aisthesis-3151	209	4	mcdermott	PERSON
aisthesis-3151	209	5	d.	NORP
aisthesis-3151	209	6	arén frontera	PERSON
aisthesis-3151	210	1	hawkins	PERSON
aisthesis-3151	210	2	r.	PERSON
aisthesis-3151	210	3	2018	DATE
aisthesis-3151	211	1	nivolumab	PERSON
aisthesis-3151	212	1	e new england journal of medicine	ORG
aisthesis-3151	212	2	12771290	DATE
aisthesis-3151	213	1	national cancer institute	ORG
aisthesis-3151	214	1	2018	DATE
aisthesis-3151	214	2	january 23	DATE
aisthesis-3151	217	1	pavlovich	PERSON
aisthesis-3151	217	2	c. p.	PERSON
aisthesis-3151	217	3	schmidt	PERSON
aisthesis-3151	217	4	l. s.	PERSON
aisthesis-3151	217	5	j. l.	PERSON
aisthesis-3151	217	6	2003	DATE
aisthesis-3151	219	1	north america	LOC
aisthesis-3151	219	2	30(3	DATE
aisthesis-3151	219	3	437	CARDINAL
aisthesis-3151	219	4	zielinski	GPE
aisthesis-3151	219	5	c. c.	PERSON
aisthesis-3151	219	6	bojic, a.	PERSON
aisthesis-3151	219	7	bojic	PERSON
aisthesis-3151	219	8	m.	PERSON
aisthesis-3151	221	1	schmidinger	PERSON
aisthesis-3151	221	2	2008	DATE
aisthesis-3151	223	1	26(32	CARDINAL
aisthesis-3151	223	2	5204-5212	DATE
aisthesis-3151	224	1	takahashi	PERSON
aisthesis-3151	224	2	srinivasan	GPE
aisthesis-3151	224	3	r.	NORP
aisthesis-3151	224	4	igarashi	GPE
aisthesis-3151	224	5	t., lundqvist	GPE
aisthesis-3151	224	6	a., su!redini	PERSON
aisthesis-3151	225	1	2004	DATE
aisthesis-3151	226	1	a&er	PERSON
aisthesis-3151	227	1	104(11	DATE
aisthesis-3151	227	2	4984	DATE
aisthesis-3151	228	1	#	CARDINAL
aisthesis-3151	228	2	r.	NORP
aisthesis-3151	228	3	kuntz	ORG
aisthesis-3151	228	4	s.	PERSON
aisthesis-3151	228	5	lohse	ORG
aisthesis-3151	228	6	c., webster	PERSON
aisthesis-3151	228	7	w.	PERSON
aisthesis-3151	229	1	kwon, e. (	PERSON
aisthesis-3151	229	2	2006	DATE
aisthesis-3151	231	1	66(7	CARDINAL
aisthesis-3151	231	2	3381	CARDINAL
aisthesis-3151	232	1	j.	PERSON
aisthesis-3151	232	2	s.	GPE
aisthesis-3151	232	3	labriola	GPE
aisthesis-3151	232	4	m., gupta	PERSON
aisthesis-3151	232	5	r. t.	PERSON
aisthesis-3151	232	6	mccall, s.	ORG
aisthesis-3151	232	7	george, d. j….	PERSON
aisthesis-3151	234	1	t.	PERSON
aisthesis-3151	234	2	2019	DATE
aisthesis-3151	236	1	607	CARDINAL
aisthesis-3151	236	2	8	CARDINAL