        item: #1 of 45
          id: cord-003360-mkv1jc7u
      author: Chen, Yirong
       title: The Effect of School Closure on Hand, Foot, and Mouth Disease Transmission in Singapore: A Modeling Approach
        date: 2018-10-22
       words: 4346
      flesch: 47
     summary: The effects of school closure due to 1) institutional outbreaks, 2) public holidays, and 3) school vacations were assessed using a Bayesian time series modeling approach. School closure was associated with a reduction in HFMD transmission rate.
    keywords: cases; closure; disease; effect; hfmd; number; outbreak; school
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        item: #2 of 45
          id: cord-253459-tcn10pho
      author: Moreau, Gregory Brett
       title: Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection
        date: 2020-07-28
       words: 2395
      flesch: 50
     summary: The major histopathology findings in infected mice were proteinaceous debris in the alveolar space, neutrophils in the interstitial space, and alveolar septal thickening ( Figure 2 ); these observations were consistent with other hACE2 mouse models, which also detected signs of lung injury including interstitial pneumonia, inflammatory cell infiltrates, and alveolar septal thickening. Our findings are consistent with other studies using hACE2 mice, which observed successful infection with SARS-CoV-2 and a milder disease severity compared with SARS-CoV-1.
    keywords: cov-2; hace2; infection; mice; mouse; sars
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        item: #3 of 45
          id: cord-255062-7ozdmb09
      author: Ogoina, Dimie
       title: Improving Appropriate Use of Medical Masks for COVID-19 Prevention: The Role of Face Mask Containers
        date: 2020-08-04
       words: 1012
      flesch: 46
     summary: Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis Face masks for the public during the COVID-19 crisis COVID-19: the need for rational use of face masks in Nigeria Decontamination of surgical face masks and N95 respirators by dry heat pasteurization for one hour at 70°C Shortage of Personal Protective Equipment Endangering Health Workers Worldwide Leather pouch (A) and plastic box (B) designed as face mask containers to safely store face masks to avoid self-and environmental contamination and promote extended use of face masks in the face of scarcity Acknowledgments: The use of face mask containers could help to promote appropriate and safe storage of face masks and facilitate extended use when medical masks are not due for replacement.
    keywords: face; masks
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        item: #4 of 45
          id: cord-255940-chb4iuis
      author: Walton, David A.
       title: Facility-Level Approaches for COVID-19 When Caseload Surpasses Surge Capacity
        date: 2020-06-26
       words: 1802
      flesch: 37
     summary: 8, 9 Modeling by Cornell University and Oxford University projects up to 430,000 people in Haiti might require hospitalization, which would require more than 9,000 additional hospital beds 10 ; however, fewer than 300 hospital beds are currently available for COVID-19 patients. Haiti offers one example, but other countries have experienced similar challenges with vulnerable populations, often leveraging unique solutions to add additional bed capacity for COVID-19 patients.
    keywords: care; covid-19; health; patients; testing
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        item: #5 of 45
          id: cord-256852-lrz17bdx
      author: Nayyar, Gaurvika M. L.
       title: Responding to the Pandemic of Falsified Medicines
        date: 2015-06-03
       words: 4209
      flesch: 31
     summary: Few functional national regulatory authorities exist in low-income nations that lack trained staff and suitably equipped laboratories to test drug quality centrally or in peripheral pharmacies or markets. The focus of all actions tied to drug quality must be on public and individual health, and strengthening national capacities to improve the health of their citizens.
    keywords: convention; counterfeit; countries; drugs; health; international; medicines; organization; pharmaceutical; products; quality
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        item: #6 of 45
          id: cord-257377-x5xijo8m
      author: Ogoina, Dimie
       title: COVID-19: The Need for Rational Use of Face Masks in Nigeria
        date: 2020-05-15
       words: 1477
      flesch: 46
     summary: The Need for Rational Use of Face Masks in Nigeria date: 2020-05-15 journal: Am J Trop Med Hyg DOI: 10.4269/ajtmh.20-0433 sha: doc_id: 257377 cord_uid: x5xijo8m Because of the pandemic of COVID-19, the federal government of Nigeria has instituted a mandatory policy requiring everyone going out in public to wear face masks. Unfortunately, the Nigeria media is awash with images of misuse and abuse of face masks by the public, government officials, and healthcare workers.
    keywords: face; masks; public
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        item: #7 of 45
          id: cord-260444-ooi5x9p3
      author: Gadelha Farias, Luís Arthur Brasil
       title: Case Report: Coronavirus Disease and Pulmonary Tuberculosis in Patients with Human Immunodeficiency Virus: Report of Two Cases
        date: 2020-08-18
       words: 2072
      flesch: 54
     summary: HIV patients with MTB latent infection have a higher risk of reactivation. In this context, the impact of COVID-19 on HIV viral replication in HIV patients with MTB latent infection and in patients with HIV and active TB must be subjects of research.
    keywords: cov-2; covid-19; hiv; mtb; patients; sars; treatment
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        item: #8 of 45
          id: cord-260871-dtn5t8ka
      author: Silva, Marcus Tulius T.
       title: SARS-CoV-2: Should We Be Concerned about the Nervous System?
        date: 2020-07-17
       words: 4122
      flesch: 36
     summary: [39] Typically, SARS patients exhibited a triphasic pattern of disease, initially presenting with fever, a nonproductive cough, sore throat, and myalgia. A novel syndrome Self-reported olfactory and taste disorders in SARS-CoV-2 patients: a cross-sectional study Entry of coronavirus into primate CNS following peripheral infection SARS-associated coronavirus Coronavirus pathogenesis Renin-angiotensin-aldosterone system inhibitors in patients with COVID-19 Angiotensin-converting enzyme 2 in the brain: properties and future directions Epidemiological and clinical features of human coronavirus infections among different subsets of patients Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method Detection of the human coronavirus 229E, HKU1, NL63, and OC43 between 2010 and 2013 in Yamagata Two coronaviruses isolated from central nervous system tissue of two multiple sclerosis patients Murine hepatitis virus-a model for virus-induced CNS demyelination Human coronaviruses: viral and cellular factors involved in neuroinvasiveness and neuropathogenesis Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human Phylogeny of the SARS coronavirus The genome sequence of the SARSassociated coronavirus Characterization of a novel coronavirus associated with severe acute respiratory syndrome The severe acute respiratory syndrome Severe acute respiratory syndrome and critical care medicine: the Toronto experience Olfactory neuropathy in severe acute respiratory syndrome: report of a case Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome Pathological findings of COVID-19 associated with acute respiratory distress syndrome Multiple organ infection and the pathogenesis of SARS Persistence of physical symptoms in and abnormal laboratory findings for survivors of severe acute respiratory syndrome Hypocortisolism in survivors of severe acute respiratory syndrome (SARS) Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice Coronavirus infection of rat dorsal root ganglia: ultrastructural characterization of viral replication, transfer, and the early response of satellite cells Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding A pneumonia outbreak associated with a new coronavirus of probable bat origin Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neurotropic mechanisms The vagus nerve is one route of transneural invasion for intranasally inoculated influenza A virus in mice CNS innervation of vagal preganglionic neurons controlling peripheral airways: a transneuronal labeling study using pseudorabies virus Middle east respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4 Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Detection of severe acute respiratory syndrome coronavirus in the brain: potential role of the chemokine mig in pathogenesis A first case of meningitis/encephalitis associated with SARS-coronavirus-2 COVID-19: consider cytokine storm syndromes and immunosuppression Guillain-barré syndrome associated with SARS-CoV-2 Miller fisher syndrome and polyneuritis cranialis in COVID-19 Pearls and oysters: facial nerve palsy as a neurological manifestation of COVID-19 infection Neurologic features in severe SARS-CoV-2 infection Large-vessel stroke as a presenting feature of COVID-19 in the young COVID-19 and its implications for thrombosis and anticoagulation D-dimer levels on admission to predict in-hospital mortality in patients with COVID-19 Central nervous system involvement by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the central nervous system Neurologic alterations due to respiratory virus infections
    keywords: acute; coronavirus; cov; cov-2; covid-19; human; infection; patients; sars; syndrome
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        item: #9 of 45
          id: cord-264140-5cxzc3z8
      author: Tam, Clarence C.
       title: Epidemiology and Transmission of Respiratory Infections in Thai Army Recruits: A Prospective Cohort Study
        date: 2018-09-04
       words: 4013
      flesch: 40
     summary: In the serology subset, the rate of influenza infection was 3.4 per 100 person-months; 58% of influenza infections resulted in clinical disease. Despite this, data from tropical settings, in which the epidemiology of influenza and other respiratory infections differs substantially from temperate settings, are limited.
    keywords: cases; illness; influenza; military; pathogens; recruits; type; uri
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        item: #10 of 45
          id: cord-270495-2u072mtp
      author: Lokida, Dewi
       title: Diagnosis of COVID-19 in a Dengue-Endemic Area
        date: 2020-08-05
       words: 1750
      flesch: 48
     summary: A novel coronavirus from patients with pneumonia in China Coinfection between dengue and COVID-19: need for approach in endemic zones Covert COVID-19 and false-positive dengue serology in Singapore Force of infection and true infection rate of dengue in Singapore: implications for dengue control and management Dengue viral infection in Indonesia: epidemiology, diagnostic challenges, and mutations from an observational cohort study Clinical and laboratory diagnosis of dengue virus infection The epidemiology, virology and clinical findings of dengue virus infections in a cohort of Indonesian adults in western Java Prolonged persistence of IgM against dengue virus detected by commonly used commercial assays Accuracy of dengue clinical diagnosis with and without NS1 antigen rapid test: comparison between human and Bayesian network model decision COVID-19 and dengue co-infection in a returning traveller To estimate the extent of this problem, we evaluated sera from 42 confirmed COVID-19 patients for evidence of DENV infection.
    keywords: covid-19; dengue; denv; igm; infection
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        item: #11 of 45
          id: cord-271906-2nm55024
      author: Quincho-Lopez, Alvaro
       title: Case Report: Pneumothorax and Pneumomediastinum as Uncommon Complications of COVID-19 Pneumonia—Literature Review
        date: 2020-07-23
       words: 1987
      flesch: 40
     summary: Emergency tracheal intubation in 202 patients with COVID-19 in Wuhan, China: lessons learnt and international expert recommendations Portable chest X-ray in coronavirus disease-19 (COVID-19): a pictorial review Coronavirus disease 2019 (COVID-19): a systematic review of imaging findings in 919 patients COVID-19 with spontaneous pneumomediastinum Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study SARS-CoV-2 pulmonary infection revealed by subcutaneous emphysema and pneumomediastinum Pneumomediastinum and spontaneous pneumothorax as an extrapulmonary complication of COVID-19 disease Spontaneous pneumothorax: epidemiology, pathophysiology and cause Spontaneous pneumomediastinum: time for consensus Spontaneous pneumothorax Systematic review of spontaneous pneumomediastinum: a survey of 22 years' data Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia Mediastinal emphysema, giant bulla, and pneumothorax developed during the course of COVID-19 pneumonia SARS-CoV-2 pneumonia with subcutaneous emphysema, mediastinal emphysema, and pneumothorax: a case report Spontaneous pneumomediastinum in COVID-19 COVID-19 with spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: case report Perforated acute abdomen in a patient with COVID-19: an atypical manifestation of the disease Spontaneous pneumothorax following COVID-19 pneumonia SARS-CoV-2 infection associated with spontaneous pneumothorax Secondary tension pneumothorax in a COVID-19 pneumonia patient: a case report Tension pneumothorax in a patient with COVID-19 Management of persistent pneumothorax with thoracoscopy and blebs resection in COVID-19 patients Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses Spontaneous pneumomediastinum occurring in the SARS-COV-2 infection Spontaneous pneumomediastinum in a patient with coronavirus disease 2019 pneumonia and the possible underlying mechanism Spontaneous pneumomediastinum: a probable unusual complication of coronavirus disease 2019 (COVID-19) pneumonia We performed a literature review of COVID-19 pneumonia cases that developed pneumothorax, pneumomediastinum, or both.
    keywords: covid-19; patients; pneumomediastinum; pneumonia; pneumothorax
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        item: #12 of 45
          id: cord-275243-knr3mat0
      author: Larsen, Kevin
       title: Detection of Pulmonary Embolism in Returning Travelers with Hypoxemic Pneumonia due to COVID-19 in Reunion Island
        date: 2020-07-01
       words: 1672
      flesch: 45
     summary: In the published literature, the incidence of thrombotic complications like pulmonary embolism or deep vein thrombosis in patients with COVID-19 pneumonia is highly variable, ranging from 1% to 20%. Moreover, it was not possible to perform a control group because the vast majority of COVID-19 patients came from Europe by long-haul flight (i.e., > 6,000 km).
    keywords: covid-19; embolism; patients; pneumonia; pulmonary
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        item: #13 of 45
          id: cord-278283-uoy54dds
      author: Chen, Hualiang
       title: Malaria in Zhejiang Province, China, from 2005 to 2014
        date: 2015-08-05
       words: 2530
      flesch: 51
     summary: Malaria incidence decreased in recent years in Zhejiang Province, but there were hundreds of imported malaria cases every year and epidemiological characteristics changed. Notably, only 7% of malaria cases were indigenous and the other cases were all imported.
    keywords: cases; disease; malaria; province; years; zhejiang
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        item: #14 of 45
          id: cord-280164-dukccrjb
      author: Nachega, Jean B.
       title: Responding to the Challenge of the Dual COVID-19 and Ebola Epidemics in the Democratic Republic of Congo—Priorities for Achieving Control
        date: 2020-06-19
       words: 2310
      flesch: 45
     summary: Third, the follow-up of COVID-19 contacts is modeled after our EVD experience using contact-tracers and community health workers (CHCWs) at the peripheral level: health areas, neighborhoods, and villages. 14 Serological testing for antiviral antibodies is unavailable in the DRC and is unsuitable for diagnosing active COVID-19 cases.
    keywords: cases; covid-19; drc; evd; health; outbreak; response
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        item: #15 of 45
          id: cord-285369-ktg2b9jb
      author: Mohamed, Mouhand F. H.
       title: Frequency of Abnormalities Detected by Point-of-Care Lung Ultrasound in Symptomatic COVID-19 Patients: Systematic Review and Meta-Analysis
        date: 2020-06-02
       words: 3225
      flesch: 46
     summary: Recent data suggested the utility of lung ultrasound (LUS) in the diagnosis of COVID-19 by detecting an interstitial pattern (B-pattern). The pooled proportion (PP) of B-pattern detected by lung ultrasound (US) was 0.97 (95% CI: 0.94–1.00 I(2) 0%, Q 4.6).
    keywords: covid-19; frequency; lung; patients; studies; ultrasound
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        item: #16 of 45
          id: cord-285428-fcrunf38
      author: Halstead, Scott B.
       title: COVID-19: The Need for Immunoprevention at Industrial Scale
        date: 2020-04-08
       words: 685
      flesch: 40
     summary: Efforts are well underway by many groups to derive monoclonal antibodies or manufacture gamma globulin from the huge cohort of COVID-19 convalescent immunes. [7] [8] In the 1950s, William McD Hammon at the University of Pittsburgh demonstrated that gamma globulin given to 100,000 children in a blinded efficacy trial successfully blunted paralysis attack rates during epidemics of poliomyelitis.
    keywords: antibodies; covid-19; gamma
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        item: #17 of 45
          id: cord-285486-99trkti1
      author: Abd-Elsalam, Sherief
       title: Hydroxychloroquine in the Treatment of COVID-19: A Multicenter Randomized Controlled Study
        date: 2020-08-14
       words: 2929
      flesch: 47
     summary: Univariate logistic regression analysis showed that HCQ treatment was not significantly associated with decreased mortality in COVID-19 patients. Diagnosis and Treatment Protocol for COVID-19 G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences Chloroquine or hydroxychloroquine for prophylaxis of COVID-19 Hydroxychloroquine for COVID-19: what is our current state of knowledge? Characteristics, treatment outcomes and role of hydroxychloroquine among 522 COVID-19 hospitalized patients in Jaipur city: an epidemio-clinical study Observational study of hydroxychloroquine in hospitalized patients with COVID-19 COVID-19 coronavirus research has overall low methodological quality thus far: case in point for chloroquine/hydroxychloroquine Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial Virological and clinical cure in COVID-19 patients treated with hydroxychloroquine: a systematic review and meta-analysis Effect of hydroxychloroquine in hospitalized patients with COVID-19: preliminary results from a multi-centre, randomized A randomized trial of hydroxychloroquine as postexposure prophylaxis for COVID-19 Hydroxychloroquine as postexposure prophylaxis for COVID-19 SARS-CoV-2: the path of prevention and control APASL COVID Task Force, APASL COVID Liver Injury Spectrum Study, 2020.
    keywords: care; covid-19; group; hcq; hydroxychloroquine; patients; treatment
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        item: #18 of 45
          id: cord-285490-tpsf05ca
      author: Solís, José Gabriel
       title: Case Report: Rhabdomyolysis in a Patient with COVID-19: A Proposed Diagnostic-Therapeutic Algorithm
        date: 2020-07-29
       words: 1796
      flesch: 33
     summary: We recommend measuring CK levels in COVID-19 patients with suggestive clinical or analytical alterations, especially in those with AKI, in which it can be a pathophysiological mechanism that requires early and aggressive treatment to prevent chronic kidney damage or death. The diagnosis of COVID-19 and severe rhabdomyolysis complicated with AKI was made.
    keywords: acute; covid-19; muscle; patients; rhabdomyolysis; sars
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        item: #19 of 45
          id: cord-286543-mtjk59rp
      author: Al-Zaman, Md. Sayeed
       title: Healthcare Crisis in Bangladesh during the COVID-19 Pandemic
        date: 2020-08-20
       words: 1814
      flesch: 53
     summary: Bangladesh hospitals forced to turn away patients Institute for Defence Studies and Analyses Bangladesh arrests hospital owner over fake coronavirus results COVID-19 fake certificates scam: JKG Healthcare's chairman Dr. Sabrina held How much the permission-based investigation in hospitals would be effective. Surprisingly, whereas many developed countries, including the United States, the United Kingdom, Italy, and Spain, have suffered greatly during the COVID-19 pandemic even with their highly efficient healthcare systems, many less developed countries with inadequate healthcare systems are surviving the crisis more easily.
    keywords: bangladesh; covid-19; health; healthcare; pandemic
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        item: #20 of 45
          id: cord-287247-vv0zc0gd
      author: Gutman, Julie R.
       title: Malaria and Parasitic Neglected Tropical Diseases: Potential Syndemics with COVID-19?
        date: 2020-06-01
       words: 4251
      flesch: 33
     summary: Susceptibility to malaria in highly endemic areas differs by age: younger children are more vulnerable to malaria infections and at a higher risk for severe malaria. Importantly, malaria infections in endemic areas frequently result in chronic, afebrile disease in older children and adults.
    keywords: children; coronavirus; cov-2; covid-19; disease; infection; lmics; malaria; ntds; sars
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        item: #21 of 45
          id: cord-294624-d71za6hi
      author: Kapepula, Paulin M.
       title: Artemisia Spp. Derivatives for COVID-19 Treatment: Anecdotal Use, Political Hype, Treatment Potential, Challenges, and Road Map to Randomized Clinical Trials
        date: 2020-07-23
       words: 2140
      flesch: 34
     summary: As the world desperately searches for new treatments to reduce rates of severe morbidity and mortality from COVID-19, the promotion of new drug discovery building on extracts from traditional medicinal plants should be encouraged. extracts for COVID-19 treatment in low-income countries has led to exaggerated and unproven claims of its efficacy in the absence of a scientific basis or results from clinical trials.
    keywords: annua; artemisia; artemisinin; compounds; covid-19; treatment
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        item: #22 of 45
          id: cord-296363-qgoxlqoq
      author: Khan, Yusra Habib
       title: Threat of COVID-19 Vaccine Hesitancy in Pakistan: The Need for Measures to Neutralize Misleading Narratives
        date: 2020-06-22
       words: 1534
      flesch: 41
     summary: Recently, two well-known political figures raised conspiracy theories against COVID-19 vaccines in Pakistan, stating that COVID-19 is a grand illusion and a conspiracy against Muslim countries. Unfortunately, a conspiracy theory against COVID-19 vaccine is currently being spread in Pakistan.
    keywords: conspiracy; covid-19; pakistan; vaccine
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        item: #23 of 45
          id: cord-296556-fr8x8j3i
      author: Chaccour, Carlos
       title: Ivermectin and COVID-19: Keeping Rigor in Times of Urgency
        date: 2020-04-16
       words: 1409
      flesch: 36
     summary: We believe the recent findings regarding ivermectin warrant rapidly implemented controlled clinical trials to assess its efficacy against SARS-CoV-2. Ivermectin and Abamectin Treating COVID-19-off-label drug use, compassionate use, and randomized clinical trials during pandemics
    keywords: drug; efficacy; ivermectin; sars; trials
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        item: #24 of 45
          id: cord-305073-8301zqj9
      author: Alhakeem, Ayat
       title: Case Report: COVID-19–Associated Bilateral Spontaneous Pneumothorax—A Literature Review
        date: 2020-07-14
       words: 1395
      flesch: 40
     summary: Review of the literature shows 18 case reports describing COVID-19 patients with spontaneous pneumothorax. This association could be secondary to underlying undiagnosed Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China Diagnosis and treatment of severe COVID-19 complicated with spontaneous pneumothorax: a case report SARS-CoV-2 infection associated with spontaneous pneumothorax Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: case report A case of spontaneous pneumothorax in COVID-19 pneumonia COVID-19 with spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema COVID-19, chronic obstructive pulmonary disease and pneumothorax: a frightening triad Tension pneumothorax in a patient with COVID-19 Mediastinal emphysema, giant bulla, and pneumothorax developed during the course of COVID-19 pneumonia Spontaneous pneumomediastinum: a probable unusual complication of coronavirus disease 2019 (COVID-19) pneumonia
    keywords: chest; covid-19; disease; pneumothorax
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        item: #25 of 45
          id: cord-306149-sd0s0jup
      author: Ratanarat, Ranistha
       title: Critical Care Management of Patients with COVID-19: Early Experience in Thailand
        date: 2020-05-18
       words: 3098
      flesch: 40
     summary: The objective of this report is to outline our initial experience with the management of COVID-19 patients requiring intensive care unit (ICU) admission. Chest computed tomography (CT) findings in COVID-19 patients are more specific, showing bilateral, multi-lobar ground-glass opacification with the so-called crazy paving.
    keywords: care; cases; coronavirus; covid-19; disease; patients; thailand; therapy
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        item: #26 of 45
          id: cord-308680-moligska
      author: Wong, Justin
       title: Epidemiological Investigation of the First 135 COVID-19 Cases in Brunei: Implications for Surveillance, Control, and Travel Restrictions
        date: 2020-08-14
       words: 4197
      flesch: 46
     summary: All confirmed COVID-19 cases were treated and isolated at the National Isolation Centre. 2 Importation events in a country with no cases can lead to an exponential increase in case numbers within a short time period.
    keywords: brunei; cases; control; covid-19; days; epidemic; measures; time
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        item: #27 of 45
          id: cord-309900-4nln90jn
      author: Doornekamp, Laura
       title: Experience with a Multinational, Secondary School Education Module with a Focus on Prevention of Virus Infections
        date: 2017-07-12
       words: 7906
      flesch: 50
     summary: A review of the research Social desirability in crosscultural research Evaluation of a school-based HIV prevention intervention among Yemeni adolescents Effects of a rapid peer-based HIV/AIDS educational intervention on knowledge and attitudes of high school students in a high-income Arab country Effectiveness of a peer-led HIV prevention intervention in secondary schools in Rwanda: results from a non-randomized controlled trial An evaluation of a peerbased HIV/AIDS education program as implemented in a suburban high school setting Effectiveness of school-based education on HIV/AIDS knowledge, attitude, and behavior among secondary school students in Wuhan Characteristics of effective interventions in improving young people's sexual health: a review of reviews Effectiveness of a school HIV/AIDS prevention program for Spanish adolescents Evaluation of HIV/AIDS secondary school peer education in rural Nigeria Longitudinal study of a school based HIV/AIDS early prevention program for Mexican adolescents Effectiveness of an HIV prevention program for secondary school students in Mongolia Peer-led health education among high school students The effect of school-based cervical cancer education on perceptions towards human papillomavirus vaccination among Hong Kong Chinese adolescent girls An educational programme on dengue fever prevention and control for females in Jeddah high schools Effects of an influenza prevention program using non-pharmaceutical prevention measures to improve the knowledge, attitudes and practices of elementary school students in Nakhon Phanom province Countries and Economies Stichting Technasium The Surinamese Education System Described and Compared with the Dutch System The Indonesian Education System Described and Compared with the Dutch System Learning effects of an international group competition project Where's the evidence that active learning works?
    keywords: attitude; behavior; country; education; group; intervention; knowledge; module; netherlands; school; students; suriname
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        item: #28 of 45
          id: cord-310868-rqmny4r2
      author: Tesfaye, Wubshet
       title: How Do We Combat Bogus Medicines in the Age of the COVID-19 Pandemic?
        date: 2020-08-18
       words: 2868
      flesch: 30
     summary: More importantly, it is imperative medicines regulatory authorities and relevant stakeholders implement robust authentication and procurement processes to ensure quality medicines supply. The prevalence of falsified medicines spans from 1% in developed settings to 10% in the Global South.
    keywords: covid-19; global; health; medicines; pandemic; products; substandard; supply
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        item: #29 of 45
          id: cord-312841-g948h572
      author: Kalkeri, Raj
       title: SARS-CoV-2 Shedding from Asymptomatic Patients: Contribution of Potential Extrapulmonary Tissue Reservoirs
        date: 2020-05-13
       words: 2701
      flesch: 26
     summary: However, SARS virus has been shown to replicate in human kidney (HEK293) and hepatic (Huh7 and HepG2) 22 cell lines and detected in the liver and brain of patients. Nonstructural proteins (NSP1, 3, and 16) and accessory proteins (ORF 3a, 6, and 9b) of SARS-CoV-2 are thought to play a role in the evasion of host immune responses (Table 3) .
    keywords: coronavirus; cov-2; covid-19; infection; patients; reservoirs; sars
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        item: #30 of 45
          id: cord-312861-6ayidmj3
      author: Rayner, Craig R.
       title: Accelerating Clinical Evaluation of Repurposed Combination Therapies for COVID-19
        date: 2020-08-21
       words: 2001
      flesch: 24
     summary: Adaptive platform trials provide capacity in combination trials to add or remove ineffective treatment arms, allowing for sequential comparisons and a perpetual design wherein treatments can be prioritized or de-prioritized as evidence accumulates. Among options for accelerated development is the evaluation of drug combinations in the absence of prior monotherapy data.
    keywords: approach; combination; covid-19; treatment; trials
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        item: #31 of 45
          id: cord-314921-u74jut63
      author: LeVine, Shankar
       title: Case Report: The First Case of COVID-19 in Bhutan
        date: 2020-04-20
       words: 1735
      flesch: 44
     summary: In a recent study, 78.6% of COVID-19 patients suffered from a lack of appetite at presentation. JAMA e201585 Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study Immune responses in COVID-19 and potential vaccines: lessons learned from SARS and MERS epidemic Evaluation of the effectiveness of surveillance and containment measures for the first 100 patients with COVID-19 in Singapore Keeping the Coronavirus from Infecting Health-Care Workers.
    keywords: bhutan; case; country; covid-19; patient
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        item: #32 of 45
          id: cord-315695-9sg7s1a1
      author: Brett-Major, David M.
       title: Advanced Preparation Makes Research in Emergencies and Isolation Care Possible: The Case of Novel Coronavirus Disease (COVID-19)
        date: 2020-03-30
       words: 3952
      flesch: 39
     summary: Federal quarantine orders-the first such use in over 50 yearspresented contextual challenges. The CDC is in a unique situation to take precedent-setting action, establishing new standards for how federal quarantine should occur in the United States for many years to come.
    keywords: care; covid-19; disease; health; isolation; nebraska; quarantine; research; study; unmc
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        item: #33 of 45
          id: cord-316712-1ngcwdln
      author: Laxminarayan, Ramanan
       title: India’s Battle against COVID-19: Progress and Challenges
        date: 2020-08-24
       words: 2593
      flesch: 51
     summary: India News, Hindustan Times Statewise estimates of current hospital beds, intensive care unit (ICU) beds and ventilators in India: are we prepared for a surge in COVID-19 hospitalizations? As of August 3, 2020, India was third in the world in the number of reported SARS-CoV-2 infections (2,456,785) and fourth in the number of reported COVID-19 deaths (48,117).
    keywords: covid-19; deaths; disease; india; infections; testing
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        item: #34 of 45
          id: cord-318994-1xngjndu
      author: Lier, Audun J.
       title: Case Report: Disseminated Strongyloidiasis in a Patient with COVID-19
        date: 2020-08-14
       words: 1971
      flesch: 38
     summary: This report describes the clinical features of a case of disseminated strongyloidiasis infection and polymicrobial bacteremia in an individual who received immunosuppressive treatment for COVID-19. We report a case of a COVID-19 patient who developed disseminated strongyloidiasis following treatment with high-dose corticosteroids and tocilizumab.
    keywords: covid-19; day; negative; strongyloides; strongyloidiasis
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        item: #35 of 45
          id: cord-321514-knyw023l
      author: Bénet, Thomas
       title: Severity of Pneumonia in Under 5-Year-Old Children from Developing Countries: A Multicenter, Prospective, Observational Study
        date: 2017-07-12
       words: 4449
      flesch: 39
     summary: Pocket Book of Hospital Care for Children Refining clinical diagnosis with likelihood ratios Epidemiology of hypoxaemia in children with acute lower respiratory infection Viral pneumonia Differentiation of bacterial and viral pneumonia in children Global burden of acute lower respiratory infections due to respiratory syncytial virus in young PNEUMONIA SEVERITY IN CHILDREN FROM DEVELOPING COUNTRIES children: a systematic review and meta-analysis Viral etiology of severe pneumonia among Kenyan infants and children Association of respiratory viruses with outcomes of severe childhood pneumonia in Botswana Human metapneumovirus: review of an important respiratory pathogen Hypoxaemia in children with severe pneumonia in Papua New Guinea Global burden of childhood pneumonia and diarrhoea Colonisation by Streptococcus pneumoniae and Staphylococcus aureus in healthy children The present study selectively comprised sites with better quality data on oxygen saturation (SO 2 ) at admission, mortality among pneumonia cases, and documented recording of patient follow-up during hospitalization.
    keywords: admission; blood; children; countries; death; hypoxemia; patients; pneumonia; study
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        item: #36 of 45
          id: cord-325498-4yciuh1n
      author: Del Brutto, Oscar H.
       title: Incident SARS-CoV-2 Infection and a Shared Latrine
        date: 2020-07-22
       words: 651
      flesch: 46
     summary: Here, we present a cluster of incident cases of SARS-CoV-2 involving a woman who lived alone (house A), and a five-member family (house B) who were seronegative during the first survey. Behind house A, house B shows four seroconverted family members (green dots) and the one that remained seronegative (white dot).
    keywords: cov-2; house
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        item: #37 of 45
          id: cord-328661-spxgox52
      author: Yu, Jianhai
       title: Epidemiological and Evolutionary Analysis of Dengue-1 Virus Detected in Guangdong during 2014: Recycling of Old and Formation of New Lineages
        date: 2019-08-05
       words: 5838
      flesch: 42
     summary: The driving force for 2014 dengue outbreak in Guangdong Multiple sources of infection and potential endemic characteristics of the large outbreak of dengue in Guangdong in 2014 Molecular epidemiology demonstrates that imported and local strains circulated during the 2014 dengue outbreak in Guangzhou Phylogenetic history demonstrates two different lineages of dengue type 1 virus in Colombia Population dynamics of DENV-1 genotype V in Brazil is characterized by co-circulation and strain/lineage replacement Phylodynamics of DENV-1 reveals the spatiotemporal co-circulation of two distinct lineages in 2013 and multiple introductions of dengue virus in Goiás, Brazil Dengue virus surveillance in Singapore reveals high viral diversity through multiple introductions and in situ, evolution Dengue in Singapore from 2004 to 2016: cyclical epidemic patterns dominated by serotypes 1 and 2 Molecular characterization of the E gene of dengue virus type 1 isolated in Guangdong province The origin of dengue viruses caused the DF outbreak in Guangdong province, China Spatial and temporal distribution characteristics of dengue fever in Guangdong province, China during Current infection status and epidemic risk analysis of dengue fever and chikungunya in Guangdong province Distribution of dengue virus serum type I in Guangdong The epidemiological characteristics and molecular phylogeny of the dengue virus in Guangdong, China Evolutionary and phylodynamic analyses of, dengue virus, serotype I in Guangdong province, China, between Molecular surveillance of dengue in semarang, Indonesia revealed the circulation of an old genotype of dengue virus serotype-1 Continuous dengue type 1 virus genotype shifts followed by co-circulation, clade shifts and subsequent disappearance in Surabaya Molecular epidemiology of dengue viruses in three provinces of Lao PDR Dengue viruses in Papua New Guinea: evidence of endemicity and phylogenetic variation, including the evolution of new genetic lineages Temporal distribution of dengue virus serotypes in Colombian endemic area and dengue incidence. The role of models in reconstructing evolutionary trees Molecular evolution and phylogeny of dengue-4 viruses Phylogeny and molecular evolution of the hepatitis C virus Molecular phylogeny and evolutionary dynamics of influenza A nonstructural (NS) gene Non Fc receptor-mediated infection of human macrophages by dengue virus serotype 2 Identification of a major determinant of mouse neurovirulence of dengue virus type 2 using stably cloned genomiclength cDNA Molecular genotyping of dengue viruses by phylogenetic analysis of the sequences of individual genes Dengue fever in mainland China Spatial analysis of dengue fever in Guangdong province Epidemic situation of dengue fever in Guangdong province Molecular epidemiology of dengue viruses in southern China from 1978 to The prevalence and endemic nature of dengue infections in Guangdong, south China: an epidemiological, serological, and etiological study from Characterizing a large outbreak of dengue fever in Guangdong province Epidemiology and characteristics of the dengue outbreak in Guangdong, southern China, in 2014 DNASTAR's Lasergene sequence analysis software Basic local alignment search tool (BLAST)
    keywords: dengue; denv1; epidemic; genotype; guangdong; lineage; molecular; outbreak; protein; province; virus
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        item: #38 of 45
          id: cord-331109-a8e7r80d
      author: Ibrahim, Yassmin S.
       title: Case Report: Paralytic Ileus: A Potential Extrapulmonary Manifestation of Severe COVID-19
        date: 2020-08-31
       words: 2365
      flesch: 42
     summary: Moreover, Bhayana et al. 20 reported bowel wall abnormalities in 31% of abdominal CT scan images in COVID-19 patients, including pneumatosis and portal venous gas. Therefore, this could be a potential mechanism of paralytic ileus in severe COVID-19 cases.
    keywords: bowel; cases; covid-19; ileus; infection; patients; sars
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        item: #39 of 45
          id: cord-340021-pj6fywwc
      author: Norooznezhad, Amir Hossein
       title: Primary Symptoms, Comorbidities, and Outcomes of 431 Hospitalized Patients with Confirmative RT-PCR Results for COVID-19
        date: 2020-06-24
       words: 1961
      flesch: 43
     summary: Thus, it seems that this study has added some new findings regarding a large number of confirmed COVID-19 patients in three age-groups by their symptoms. This analytical cross-sectional study was performed in Farabi and Imam-Reza hospitals as two designated centers for COVID-19 patients hospitalization by the Ministry of Health in Kermanshah (a western province), Iran.
    keywords: covid-19; patients; pcr
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        item: #40 of 45
          id: cord-342790-70vn1nrm
      author: Rosenthal, Philip J.
       title: Keep Politics out of Funding Decisions for Medical Research and Public Health
        date: 2020-07-22
       words: 1129
      flesch: 44
     summary: As leaders of the society, we are compelled to speak up for the integrity of science, and specifically for research funding and public health decisions based on merit, with policies rooted in data. The WHO was founded in 1948 to coordinate international health policy, establish global disease surveillance networks, and lead disease control and eradication programs.
    keywords: health; pandemic; research
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        item: #41 of 45
          id: cord-344503-gw5d721n
      author: Yousefzadegan, Sedigheh
       title: Case Report: Death due to COVID-19 in Three Brothers
        date: 2020-04-10
       words: 958
      flesch: 55
     summary: Considering the fact that most of them who are affected by COVID-19 recover, deaths in three brothers who lived separately and had no known underlying disease suggest genetic predisposition to COVID-19 in some individuals. Considering the fact that most of them who are affected by COVID-19 recover, deaths in three brothers who lived separately and had no known underlying disease suggest genetic predisposition to COVID-19 in some individuals.
    keywords: brothers; covid-19
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        item: #42 of 45
          id: cord-345067-kummh0g7
      author: Nachega, Jean B.
       title: Mobile Health Technology for Enhancing the COVID-19 Response in Africa: A Potential Game Changer?
        date: 2020-05-29
       words: 1180
      flesch: 46
     summary: How USSD Code Is Breaking Grounds in Ghana -Part COVID-19: Our Response in Senegal South Africa Is Hunting Down Coronavirus with Thousands of Health Workers Mobile phone-delivered reminders and incentives to improve childhood immunisation coverage and timeliness in Kenya (M-SIMU): a cluster randomised controlled trial A hybrid mobile approach for populationwide HIV testing in rural east Africa: an observational study Controlling ebola through mHealth strategies COVID-19 AND MOBILE HEALTH TECHNOLOGY IN AFRICA [4] [5] [6] The Global System for Mobile Communication Association reports that 50% of Africans own mobile phones and that 39% are internet-connected, numbers which are rapidly increasing, and approach 80% access when phone-sharing is considered.
    keywords: africa; covid-19; health; mobile; technology
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        item: #43 of 45
          id: cord-345554-x9q6pqgw
      author: Kay, Alexander W.
       title: It Ain’t Over Till It's Over: The Triple Threat of COVID-19, TB, and HIV
        date: 2020-08-31
       words: 1244
      flesch: 48
     summary: Importantly, novel technology that has been developed for COVID-19 contact tracing could be an important tool to increase efficiency of contact tracing of TB patients. Although these patients ultimately recovered, the authors note the challenge of delaying ARTs because of TB treatment.
    keywords: covid-19; hiv; infection
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        item: #44 of 45
          id: cord-348192-ibohbjfb
      author: Odih, Erkison E.
       title: Could Water and Sanitation Shortfalls Exacerbate SARS-CoV-2 Transmission Risks?
        date: 2020-06-09
       words: 2678
      flesch: 36
     summary: On the other hand, it is possible that only very high counts of SARS-CoV-2 would yield orally infectious doses. The ecological dynamics of fecal contamination and Salmonella Typhi and Salmonella Paratyphi A in municipal Kathmandu drinking water The impact of combined sewage overflows on the viral contamination of receiving waters Slum health: arresting COVID-19 and improving well-being in urban informal settlements Evidence of airborne transmission of the severe acute respiratory syndrome virus Environmental transmission of SARS at amoy gardens Leveraging Africa's preparedness towards the next phase of the COVID-19 pandemic Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage Pathogen surveillance in the informal settlement, Kibera, Kenya, using a metagenomics approach Letter to the editor: wastewater-based epidemiology can overcome representativeness and stigma issues related to COVID-19 The moment to see the poor Impact of rotavirus vaccination varies by level of access to piped water and sewerage: an analysis of childhood clinic visits for diarrhea in Peru SANITATION SHORTFALLS RISK SARS-CoV-2 FECO-ORAL TRANSMISSION
    keywords: cov-2; risk; sanitation; sars; transmission; wastewater; water
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        item: #45 of 45
          id: cord-355850-jgcjscjq
      author: Elhadi, Muhammed
       title: Assessment of Healthcare Workers’ Levels of Preparedness and Awareness Regarding COVID-19 Infection in Low-Resource Settings
        date: 2020-06-18
       words: 3420
      flesch: 43
     summary: We focused on healthcare workers who may come into direct contact with COVID-19 patients, and are thus expected to have adequate knowledge and preparedness. 25, 26 The majority of healthcare workers (77.4%) felt personally unprepared to address COVID-19 infection.
    keywords: covid-19; doctors; healthcare; knowledge; nurses; preparedness; study; workers
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