







































Volume 03 Issue 08-2023 15 

                 

 
 

   
  
 

American Journal Of Agriculture And Horticulture Innovations  
(ISSN – 2771-2559) 
VOLUME 03 ISSUE 08    Pages: 15-22 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 7. 471)  
OCLC – 1290679216   

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
Publisher: Oscar Publishing Services 

Servi 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ABSTRACT 

In this article, Rubia tinctoru L technology of obtaining a dry extract of a medicinal plant . Rubia tinctoru L the plant It 

is used in medicine and folk economy and dyeing fabrics and materials natural chemicals extracted from plants as 

paint their uses are highlighted. 

KEYWORDS 

Rubia tinctoru L , Rubia iberica, technology, alizarin, anthracene, ruberythric acid, galiosin, purpurin, xanthopurpurin, 

pseudopurpurin, rubiadin-glucoside, munistin, lucidin, ibericin, urinary tract stone, kidney stone, gall bladder stone, 

gout , cotton, fabric, natural dye. 

INTRODUCTION

  Research Article 

 

PAINTER ROYAN TECHNOLOGY OF OBTAINING DRY EXTRACT OF 

PLANT ROOTS 
 

Submission Date: August 20, 2023, Accepted Date:  August 25, 2023,  

Published Date: August 30, 2023  

Crossref doi: https://doi.org/10.37547/ajahi/Volume03Issue08-04 

 

 

Asishmuratova 
Institute Of Bioorganic Chemistry Named After Academician Ossadikov Of The Uzrfa, Uzbekistan 

 

BT Ibragimov 
Institute Of Bioorganic Chemistry Named After Academician Ossadikov Of The Uzrfa, Uzbekistan 

 

Astoraev 
Institute Of Bioorganic Chemistry Named After Academician Ossadikov Of The Uzrfa, Uzbekistan 

 

Jmashurov 
Institute Of Bioorganic Chemistry Named After Academician Ossadikov Of The Uzrfa, Uzbekistan 

 

TA Khajibaev 
Institute Of Chemistry Of Plant Substances Named After Academician S. Yu. Yunusov Of The Faculty Of Arts Of 

The Republic Of Uzbekistan, Uzbekistan 

 

AX Islamov 
Institute Of Bioorganic Chemistry Named After Academician Ossadikov Of The Uzrfa, Uzbekistan 

Journal Website: 

https://theusajournals.

com/index.php/ajahi 

Copyright: Original 

content from this work 

may be used under the 

terms of the creative 

commons attributes 

4.0 licence. 

 

https://theusajournals.com
https://doi.org/10.37547/ajahi/Volume03Issue08-04


Volume 03 Issue 08-2023 16 

                 

 
 

   
  
 

American Journal Of Agriculture And Horticulture Innovations  
(ISSN – 2771-2559) 
VOLUME 03 ISSUE 08    Pages: 15-22 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 7. 471)  
OCLC – 1290679216   

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
Publisher: Oscar Publishing Services 

Servi 

Today's per day on a global scale extensive measures 

are being taken to organize scientific research at a high 

level in the direction of developing the creation of 

effective drugs based on local raw materials and to 

provide the national pharmaceutical market with 

quality drugs. On the basis of the measures 

implemented in this direction, a number of important 

practical results are being achieved in terms of 

organizing the development of competitive 

preparations based on natural plant raw materials. As 

it is known , studying the biology of Rubia tinctorum 

plant species, which has been used by people for many 

years, and preparing a cheap and high-quality medicine 

that replaces imports by separating natural medicines 

from local raw materials is the first step. creation of 

material bases is of urgent importance. Such 

preparations can be isolated from the medicinal plant 

Rubia tinctorum and used in medical practice and folk 

economy. 

THEORETICAL PART 

Dyed roan - Rubia tinctorum L. and Georgian roan 

Rubia iberica C. Koch. (Rubia tinctorum L. var. Iberica 

Fisch. ex DC) belongs to the Rubicaeae family. It is 

found in Ukraine, Moldova, in the south and southeast 

of the European part of Russia, in the Caucasus 

(Azerbaijan, Georgia, Armenia, Dagestan) and Central 

Asia. in Uzbekistan Basically ditch on the sides , bushes 

_ between , channels along , in the fields and in the 

gardens grows [1-4] 

 Colorful dream The species of the plant is a perennial 

plant with a height of 30-150 cm. The rhizome is long, 

creeping, branched, cylindrical, thick, jointed, multi-

headed. The stem is covered with several, four-

pointed, jointed, spiky and looped coarse hairs. The 

leaf is oval-ovate, shiny, the veins on the lower side are 

covered with coarse hairs with loops, and they are 

arranged in bundles of 4-6 on the stem with a very 

short band. The flowers are small, greenish-yellow in 

color, gathered in a semi-umbrella growing from the 

axils of the leaves, forming a bag-shaped inflorescence. 

The calyx is not clearly known, the corolla is 5, united, 

funnel-shaped, the paternity is 5, the maternal node is 

2-digit, located below. The fruit is a 1-2-seeded, 

spherical, first red, later turning black wet fruit. It 

blooms in June-August, the fruit ripens in August-

September. Rubia tinctorum . 

 

 



Volume 03 Issue 08-2023 17 

                 

 
 

   
  
 

American Journal Of Agriculture And Horticulture Innovations  
(ISSN – 2771-2559) 
VOLUME 03 ISSUE 08    Pages: 15-22 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 7. 471)  
OCLC – 1290679216   

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
Publisher: Oscar Publishing Services 

Servi 

Figure 1. Colorful dream Above ground and below (root) part of the plant 

Colorful dream The finished product of the harvested plant consists of rhizomes and root pieces. The thickness of 

rhizome pieces depends on the year they were dug up from the ground. One-year-olds are thin, two-year-olds are 

thick, and they get thicker every year. The upper side is reddish brown. When it is cut crosswise, the bark layer is red-

brown, and the wood part is red. The product has a characteristic weak smell, sweeter at first, and then a slightly sour 

and bitter taste. The rhizome turns the water brownish-red. The underground part (root) of the Rubia tinctorum plant 

is shown to be thin in the first year and to grow in the second and third year (Fig. 2). 

 

Figure 2. Colorful dream The root of the plant is thin in the first year and grows in the second and third year 

Colorful dream the moisture content of the product 

harvested from the plant is 13%, total ash is 10%, other 

parts of the plant (stems, leaves, etc.) are 1.5%, organic 

compounds are 1% and mineral compounds are more 

than 1%, the content of the product the amount of 

anthraglycosides (those united in the form of 

glycosides) should not be less than 3% [5-7] .  

rhizome of Rubia tinctorum contains up to 5-6% 

anthracene compounds (alizarin, ruberythric acid, 

galiosin, purpurin, xanthopurpurin, pseudopurpurin, 

rubiadin-glucoside, munistin, lucidin, ibericin, etc.). 

         

Anthracene Alizarin Ruberythric acid 

      



Volume 03 Issue 08-2023 18 

                 

 
 

   
  
 

American Journal Of Agriculture And Horticulture Innovations  
(ISSN – 2771-2559) 
VOLUME 03 ISSUE 08    Pages: 15-22 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 7. 471)  
OCLC – 1290679216   

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
Publisher: Oscar Publishing Services 

Servi 

Purpurin Pseudopurpurin lucidin 

In addition to anthracene products, organic acids in plant roots contain up to 15% sugars, proteins, pectin substances, 

ascorbic acid , and citric, malic, and tartaric acids. occurs. 

        

ascorbic acid       citric acid          malic acid        tartaric acid 

The root of Rubia tinctorum plant contains carbohydrates, phenolic acids and their derivatives, coumarin, 

anthraquinone, triterpenoids, flavonoids (quercetin, kaempferol, apigenin). 

 
antiroquinone quercetin kaempferol apigenin 

Colorful dream In medicine, the plant has antispasmodic and diuretic effects, as well as softening of kidney stones 

(phosphates). Therefore, medicinal preparations are used in ureteral stones, kidney stones, gall bladder stones and 

gout . [5-7] 

Colorful dream In addition to the medicinal use of the plant, dyeing with natural chemicals extracted from the royan 

plant as a natural dye for dyeing threads, glam, fabrics, and materials grown in our Republic, which is mainly produced 

from silk and cotton , leads to an increase in the number of jobs [ 5-7], (Fig. 3). 

 



Volume 03 Issue 08-2023 19 

                 

 
 

   
  
 

American Journal Of Agriculture And Horticulture Innovations  
(ISSN – 2771-2559) 
VOLUME 03 ISSUE 08    Pages: 15-22 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 7. 471)  
OCLC – 1290679216   

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
Publisher: Oscar Publishing Services 

Servi 

Figure 3 . Colorful dream yarn dyed with natural chemicals extracted from plants 

DISCUSSION OF RESULTS 

Today's in the day a new product developed in the field 

of pharmaceuticals and medicine through a scientific 

approach based on natural medicinal plants in the 

world  if a bioactive additive (BFQ) is created and put 

into production and jobs are created, the number of 

unemployed is reduced and Satisfying the internal 

demand of our republic and creating the opportunity 

to export abroad  according to many our scientists 

scientific research are taking Colorful dream "ZPG 150" 

that allows drying of 200 l of solution per hour in the 

scientific and technological center adapted to GMP 

conditions, launched in cooperation with the scientists 

of the Institute of Bioorganic Chemistry named after 

academician OSSadikov of the UzR FA . » (PRC) 

experiments were carried out in the device that allows 

extraction methods to be carried out in a spray drying 

extractor as follows. Paint coating on the extraction 

device plant 10.0 kg was crushed into 4-6 mm size and 

100.0 l (hydromodule 1:10) of 80% etonol was poured , 

then water vapor was sent to the "steam jacket" of the 

extractor and heated to a temperature of 60 C. 

heated and left for 24 hours. The extract is drawn from 

the lower part of the extractor by a specially installed 

pump, driven in a specially equipped rotor equipment 

with 80% ethanol , and dyed. Aqueous extract of the 

plant was collected and poured. The extraction 

process was carried out under the same conditions as 

the first one. For this purpose, another 100.0 l 

(hydromodule 1:10) of 80% etonol was prepared from 

the extracted ethanol and drained from the upper part 

of the extractor again by raining. extraction was 

performed three times in this way. At the end of the 

extraction process, the extract (60, l) was poured and 

the results were analyzed (Table 1). 

Table 1 

Rubia tinctorum plant with 80% ethanol under 60 C temperature  

Number 

of extract 

infusions 

Raw material 

weight kg 

Extraction 

time, hours 

Raw 

materials 

and 80% 

ethanol 

80% ethanol extract 

(ml) 

Station % 

1 10 24 1:10 100 - 

2 again 24 1:10 100 - 

3 again 24 1:10 100  

total 10 24 1:10 300 16.9 

Production and drying of Rubia tinctorum dry extract 

technological general block sx was developed . Rubia 

tinctorum plant is crushed in a mill (1) in size 4-6 mm, 

weighed on a scale (2), placed in an extractor (5) in the 

amount of 10 kg, and from a scale (3, 4) 100 l 

(hydromodule 1:10) 80 % etonol was placed and stewed 

for a day for 24 hours. In this method, the raw material 

was extracted 3 times. The resulting 280 l extract was 

filtered on a notch filter (8) and collected in a vessel (9) 

and condensed in a vacuum evaporator (10) until 25 l, 



Volume 03 Issue 08-2023 20 

                 

 
 

   
  
 

American Journal Of Agriculture And Horticulture Innovations  
(ISSN – 2771-2559) 
VOLUME 03 ISSUE 08    Pages: 15-22 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 7. 471)  
OCLC – 1290679216   

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
Publisher: Oscar Publishing Services 

Servi 

i.e. 15% dry residue, and cooled (12). Then (13) was 

poured into a vessel and spray-dried in an Anhydro No. 

2 (Denmark) device . It was dried in a spray dryer with 

hot air inlet at 170°C, outlet at 80°C, air pressure 0.2 

MPa for 50 minutes (RS-12). The dry extract substance 

(M-16) with a content of not less than 16-17% of the 

obtained product was crushed and packaged as a 

finished product. The technological process and device 

scheme for extracting dry extract from the plant was 

developed (Scheme 1). 

Scheme 1 

Technological scheme of the process of obtaining the substance " Rubia tinctorum ". 

 

(1-mill, 2-weighing, 3,4- (60°C 80% etonol) tank, 5,6,7-extractor, refrigerator, trolley for shot, 8-filter, 9-container for 

filtered extract, 10 -vacuum evaporator equipment, 11-container for extracted solvent, 12-(for settling) separation 

funnel, 13-container, RS-12 spray dryer, M-16 grinder, 17- drying cabinet . 

Colorful dream The appearance of the substance obtained by the extraction method of the plant root extract in 80% 

ethanol in a spray drying extractor is presented in (Fig. 4). 



Volume 03 Issue 08-2023 21 

                 

 
 

   
  
 

American Journal Of Agriculture And Horticulture Innovations  
(ISSN – 2771-2559) 
VOLUME 03 ISSUE 08    Pages: 15-22 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 7. 471)  
OCLC – 1290679216   

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
Publisher: Oscar Publishing Services 

Servi 

 
Figure 4. Colorful dream the substance of the root of the plant and its extract in 80% ethanol. 

Colorful dream The root extract of the plant in 80% 

ethanol was extracted by spray drying extractor. In the 

spray dryer, the inlet of the hot air stream was set to 

170°С, and the outlet to 80°С. The amount of the 

obtained product is not less than 16-17% dry extract 

substance was crushed and packaged as a finished 

product.  

CONCLUSION 

1. A painting The protective substance was extracted 

by spraying the extract of the root of the plant in 80% 

ethanol in an extractor , and it was determined that the 

amount of the obtained product should not be less 

than 16-17%.  

2. Colorful dream When extracting the substance of 

the root of the plant in the spray drying device , the 

inlet of the hot air stream was set at an average of 

170°C, and the outlet at 80°C. 

REFERENCES 

1. Life is natural. V 6 t. T. 5. Ch. 2. Tsvetkovye rasteniya 

/ P od ed. A. L. Takhtadzhyana . - M.: 

Prosveshchenie, 1981. - S. 358. 

2. Botany. Encyclopedia "Vse rasteniya mira" / Per. 

English (ed. Grigorev D. and Dr.) - Konemann , 2006 

(Russian edition). -S . 802. - ISBN 3-8331-1621-8 . 

3. Pharmacognosy (H. Kholmatov, O'. Ahmedov) Abu 

Ali ibn Sina Tashkent 1997. 

4. Kh.Kholmatov, O'.A.Ahmedov, Pharmacognosy: 

textbook, Tashkent, NMB named after Ibn Sina, 

1995. 

5. Islamov. A.Kh., Ishmuratova.A.S., 

Gaybullaeva.O.O., Kadirova.Sh.O. 

,Tashpulatov.F.N., Khudoynazarov.M., 

Abdug'aniev.A., G'aniev.Q. // Medicinal use of the 

root of Rubia Tinctorum L and determination of 

micro and macroelements // O' zMU modern status 

and prospects of functional polymers science 

professors and young scientific-practical 

conference of scientists materials (March 19-20, 

2020) B.315-316 

6. Ishmuratova AS , Islamov AX , Abdimalikov II // 

Ruby tintorum l plant mineral elements of the root 

and in medicine application // ARES, Academic 

Research In Educational Sciences Volume 3 . Issue 

5 . 202 2 \ 05 . ISSN :2181-1385 . Gite - Factor : 0,89 / 

SIS :1,12 SJIF 5,7 / UIF :6,1 DOL :10.24412/2181-1385- 

2022-5-1214-1220 

7. Ishmuratova AS Islamov A.Kh. // DETERMINATION 

OF THE TOXICITY OF RUBIA TINCTORUM L. ROOT 

EXTRACT// Acad. S. Yu. Yunusova Institut khimii 

rastitelnyx veshchestv AH RUz mejdunarodnaya 

nauchno-teknicheskaya konferensiya Aktualnye 



Volume 03 Issue 08-2023 22 

                 

 
 

   
  
 

American Journal Of Agriculture And Horticulture Innovations  
(ISSN – 2771-2559) 
VOLUME 03 ISSUE 08    Pages: 15-22 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 7. 471)  
OCLC – 1290679216   

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
Publisher: Oscar Publishing Services 

Servi 

problemy khimii prirodnyx soedineniy 

posvyashchaetsya 80-letiyu akademii nauk 

respubliki uzbekistan 15-16 marta. Tashkent, 2023.- 

P .-164.  

 

 


