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 VOLUME Vol.05 Issue06 2025 

PAGE NO. 15-18 

DOI 10.37547/ajbspi/Volume05Issue06-04 

 
 
 
 

Analysis Of Medicinal Plants Against Diabetes And 

Collections Based On Them, As Well As Bioactive 

Additions 
 

Jalilov Utkirbek Mamarakhimovich 

Tashkent Pharmaceutical Institute, Department of Drug Technology, UZ senior lecturer, Uzbekistan 

 

Kasimov Saidali Doniyorbek ugli 

Tashkent Pharmaceutical Institute, Master's student in the specialty "Technology of Medicines and Preparations", Uzbekistan 

 

Received: 14 April 2025; Accepted: 10 May 2025; Published: 17 June 2025 

 

Abstract: This article provides information about medicinal plants used in medicine against diabetes, as well as in 
its prevention, and remedies, compositions, substances obtained on their basis, and their technologies. During 
the research, the results of studying dozens of representatives of local medicinal plants and their individual 
properties, as well as the properties of their collections, indications for use, in the treatment of diabetes mellitus, 
the beneficial properties of medicinal plants and collections, and their technological properties are presented. 

 

Keywords: Diabetes, sugar content, glucose, insulin, cumulative, diet, metabolism, extract, phytotea, bioactive 
supplement, technology, medicinal plants. 

 

Introduction: Diabetes mellitus is a metabolic disorder 
characterized by a decrease in insulin levels in the 
blood and an increase in glucose levels. In the 
treatment of diabetes, antidiabetic drugs are of great 
importance. One of the important directions in 
medicine is the use of herbal preparations with mild 
effects, low side effects, and high effectiveness. For the 
prevention and treatment of diabetes, medicinal plants 
containing a number of biologically active substances 
are used. 

In developed modern medicine, herbal remedies used 
in the treatment of diabetes mellitus are of great 
importance due to their relative harmlessness, healing 
properties, including normalizing blood glucose levels, 
anti-obesity, and other properties. Plant preparations 
and formulations with an antidiabetic effect are used 
to stimulate insulin production processes and facilitate 
digestion[1]. 

In the field of endocrinology, various blood sugar-
lowering agents are recommended as an antidote to 
diabetes and concomitant diseases caused by a 
decrease in insulin levels. 

Depending on the technology of obtaining medicinal 

plant preparations and complexes against diabetes 
mellitus, various extracts can be obtained from ground 
plant materials. These extracts contain several 
medicinal substances isolated using various separators, 
and also in the crushed plant material during the 
preparation of the compositions, biologically active 
substances are fully present. 

Purpose of the research: development, analysis, 
generalization of drugs, biologically active substances, 
and kits with antidiabetic effects and their 
technologies. 

METHODS 

When obtaining extracts from medicinal plants, the 
selection of the extractant is carried out depending on 
the type of plant, the part of the raw material, and the 
groups of biologically active substances contained in it. 
Usually, various potent ethyl alcohol, water, essential 
oils, or other separators are used in work processes. 
Extraction processes utilize maceration, percolation, 
and ultrasonic extraction methods [2]. 

One of the promising methods is obtaining extracts 
using ultrasonic extraction. In ultrasonic extraction, the 
plant is soaked in a separator and subjected to 

 

https://doi.org/10.37547/ajbspi/Volume05Issue06-04
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American Journal of Applied Science and Technology (ISSN: 2771-2745) 
 

 

ultrasonic exposure, in which the plant tissues are 
subjected to high-speed vibrations under high pressure 
and vacuum due to the phenomenon of cavitation. As 
a result, organic substances in tissues, including 
substances that can be released into the excretory 
medium, are released into the excretory medium, i.e., 
the extraction process occurs. With this method, it is 
possible to carry out extraction processes both in the 
laboratory and on an industrial scale. 

Below, taking into account the demand and interest in 
medicines based on medicinal plants, including 
antidiabetic preparations and kits, information is 
provided on the main antidiabetic drugs and medicinal 
plant-based kits, their mechanisms of action, 
indications for use and features of use, technologies for 
obtaining them, and the use of products obtained from 
various medicinal plants in medical practice. 

RESULTS 

Below are several plants, assortments, and biologically 
active supplements used in the treatment of diabetes 
mellitu 

Beans (Galega officinalis) - a rhizomatous perennial 
herbaceous plant of the legume family, the aerial part 
of which is used in folk medicine for the treatment of 
snake bites, infections, edema, as well as for milk loss 
in breastfeeding women. In modern medicine, 
biologically active additives with antidiabetic, diuretic, 
diaphoretic, lactogenic, and anthelmintic effects are 
produced from it. 

Properties of medicinal peas: helps reduce blood sugar 
levels, normalizes metabolism, restores kidney 
function, gently removes excess fluid from the body, 
stimulates milk production in nursing mothers, 
eliminates inflammation, and fights infections. Beans 
are also included in antidiabetic formulations[5]. 

Bean peel (Phaseolus) is a typical genus of annual 
plants of the legume family, with about 97 species 
found in warmer regions of the world. In addition to 
proper hypoglycemic properties, it has anti-
inflammatory and anti-rheumatic, as well as diuretic 
and antibiotic effects. They dissolve stones in the 
bladder and kidneys, lowering blood pressure. Due to 
the high content of valuable substances in bean pods, 
they are widely used for medicinal purposes. Medicinal 
and beneficial properties of bean peel: reducing blood 
sugar levels, fighting excess weight, eliminating 
hypersensitivity and hypertension, anti-rheumatic 
effect, diuretic, removal of kidney stones, elimination 
of skin diseases, treatment of chronic pancreatitis and 
cardiovascular pathologies. In medicine, decoctions 
and infusions are made from bean peel, and it is also 
included in antidiabetic formulations. 

Use in diabetes mellitus (when sugar levels increase), at 
home. The peels are ground into powder using a coffee 
grinder and 400 ml of boiling water is poured over 50 g 
of raw material. After 12 hours of infusion, take 120 ml 
before meals. 

Safflower (Salvia) or sage is a large genus of perennial 
herbaceous plants and shrubs belonging to the 
Lamiaceae family. Preparations made from the aerial 
parts (leaves and flowers) of medicinal sage have a 
sugar-lowering, anti-inflammatory, astringent, 
antiseptic, hemostatic, softening, and diuretic effect, 
reducing sweating. Mavrak is also used in the form of a 
decoction or infusion for stomatitis, bleeding gums, as 
a astringent and antiseptic for rinsing the mouth in 
tonsillitis, and in the form of sprinklers for 
gynecological diseases. The medicinal sage plant 
inhibits lactation in nursing mothers and has a positive 
effect on gastritis, colitis, stomach ulcers, meteorism, 
and gallbladder inflammation. 

It has been established that sage extract helps reduce 
blood glucose levels in rats with type 1 diabetes by 
activating a specific receptor. When these receptors 
are activated, they can cleanse the blood of excess free 
fatty acids. This improves insulin sensitivity. Another 
study on mice with type 2 diabetes showed that sage 
tea has the same effect as metformin, which regulates 
blood sugar levels in people with the same disease[4]. 

Dandelion (Taraxacum) is the most popular species of 
the dandelion genus of the Dandelion family. It is a 
perennial herbaceous plant, reaching a height of 10-40 
cm. Its distribution range extends throughout the CIS, 
except for the far north. The flowers, leaves, and roots 
of dandelion are used in medicine as a healing remedy. 
The presence of bitter glycosides, taraxerolic 
compounds, and other substances in the composition 
of dandelion root has been established. Its roots are 
also a sugar-lowering, choleretic, appetite-stimulating, 
and gastric-inducing compound tea. 
Antihyperglycemic, antioxidant, and anti-inflammatory 
properties of dandelion helped in the treatment of 
patients with type II diabetes mellitus. The roots of the 
plant contain soluble fiber (inulin). Moving throughout 
the body in an undigested form, it helps slow down the 
absorption of sugar into the bloodstream by improving 
long-term control of blood sugar levels [3]. 

Stevia (Stevia) is a genus of perennial plants belonging 
to the Asteraceae family, comprising approximately 
260 herbaceous and shrub species that grow mainly in 
the Americas. Crushed leaves of honey stevia have long 
been used as a natural sweetener, and now as a sugar 
substitute due to the growing need for low-
carbohydrate and low-sugar diets. Plant leaves, their 
aqueous extract, and isolated glycosides (stevioside 



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American Journal of Applied Science and Technology (ISSN: 2771-2745) 
 

 

and rebaudioside) are typically used as sweeteners. 
Stevia leaves are 30 times sweeter than sucrose, and 
the isolated steviazides are 250-300 times sweeter. 
Unlike artificial sweeteners (such as cyclamate and 
saccharin), stevia is not only not carcinogenic but, on 
the contrary, very beneficial. Stevia is low in calories, 
does not contain glucose, and therefore is absorbed 
without the help of insulin, which is very important for 
diabetics [6]. 

Ginko biloba (Ginko biloba) is currently the only 
representative of the gymnosperm family of the ginkgo 
family. The tree reaches a height of up to 40 m and a 
diameter of up to 1 m; young seedlings resemble some 
coniferous trees. It grows wild only in some parts of 
China. It is cultivated in southern Crimea and on the 
Black Sea coast of the Caucasus. Extract obtained from 
the leaves of Ginco biloba is used in medicine to 
improve the function of small blood vessels. It is also 
widely used for improving brain function, diabetes, and 
other purposes [7-8]. 

Cichorium intybus is a perennial herb with a thick root, 
belonging to the Asteraceae family. It is used as a 
medicinal plant and among the people as a spice, as 
well as a substitute for coffee. The famous Abu Ali ibn 
Sina used sachratqi to treat diseases of the 
gastrointestinal tract and eyes, eye inflammation, and 
gout. In modern medicine, sachratqi has found a wide 
variety of applications due to its beneficial medicinal 
properties (calming, sugar-lowering, astringent, 
choleretic, diuretic, anti-inflammatory, antipyretic, 
anthelmintic properties). The anti-diabetic and anti-
obesity effect of chicory is valuable due to the high 
content of the high-molecular-weight polysaccharide 
inulin in its roots. It is inulin that helps reduce blood 
sugar levels, improve metabolism and digestion, 
therefore, all its properties are considered important in 
the complex prevention and treatment of diabetes. 

Phytodiabetol syrup 250ml. Produced in Russia 
(Bioinventika LLC). Use: in diabetes, as a source of 
vitamins. Composition: blueberry branches, common 
bean peel, medicinal gallega herb, bird cherry herb, 
great ash root, water extract of cinnamon rosehip fruit, 
vitamin E420, E440, vitamin 9-14 premix (vitamin C, 
vitamin B1, vitamin B6, vitamin B3, vitamin B5, vitamin 
B9, vitamin H, vitamin B12), E202. Take 15 ml 3 times a 
day [10]. 

Diabefit tea. Supports pancreatic function, improves 
metabolism and mood. Composition: dandelion root, 
mint leaf, chamomile flower, cherry grass, valerian 
root, thyme root, oat straw, flaxseed, bean pods. 
Method of use: 1 filter bag of 2 g is placed in a beaker 
(200 ml), hot water is poured over it, and it is steeped 
for one night. The infusion is taken 200 ml 3 times a day 

after meals. The duration of admission is from 15 to 30 
days[11]. 

STOP Diabetic Elixir, 300 mg 180 Oil Capsule. Plant 
extracts of chamomile, beans, bean pods based on 
unrefined flaxseed oil, omega-3 and gelatin mass [12]. 

FITOCHOY GLYUNORM. Filter-package 25 pieces per 1 
gram. Manufactured by Zamona Rano company. 
Properties of tea: to normalize carbohydrate 
metabolism, normalizes metabolism, especially 
carbohydrate metabolism, to support pancreatic 
function, to prevent the development of carbohydrate 
metabolism disorders (diabetes mellitus), 
recommended as an additional source of biologically 
active substances. Composition: leaves of nettle (Folia 
urticae), young shoots of blueberry (Myrtilliherba), wild 
geranium (Herba hyperici), wild buttercup (Herba 
hypericiscabri, dagaldalachoyoti), field horsetail 
(Herbaequisetiarvensis), nettle (Herba bidentis), 
chamomile (Flores chamomillae), blueberry fruits 
(Myrtilli fructus), rosehip fruit (Fructus Rósae), tall 
andiz or (Rhizomata et radices Inulae, andiz root bark), 
large andiz (Rhizomataetradices Inulaegrandis, andiz 
yellow root). Preparation and dosage: 500 ml over 2 g 
of herbal tea (2 packets for single brewing) 

CONCLUSION 

Medicinal plants, formulations, and biologically active 
supplements are important in the treatment of 
diabetes. They are lighter and harmless compared to 
synthetic agents, do not harm the body, and allow their 
use in patients in need of constant medications, such as 
diabetes. In the treatment of diabetes, it is possible to 
use a single plant product or several plant groups. 
Plant-based phytopreparations recommended for the 
treatment of diabetes have some drawbacks. Their 
weak effect and limited effectiveness in acute cases 
necessitate their combination with other treatment 
methods when necessary. Phytotherapy is constantly 
developing, increasing the scope and interest in its use 
due to the accumulated experience and positive results 
of treatment. 

REFERENCES 

https://med24.uz/ru/bolezn/saxarnyy-diabet 

Hasanov.J.H., Usmanov.K.I., Avezov.T.A. Forecasting 
the duration of the process by applying neural 
networks to the high-critical extraction process // 
Pharmaceutical Bulletin of Uzbekistan//-2017- No1-25-
31. Tashkent. 

I.J. Karomatov, M.S. Davlatova. "Treatmental 
properties of the medicinal plant dandelion." "Biology 
and Integrative Medicine" No. 9 (26) October 2018, pp. 
147-156. 

Salvia officinalis (Sage) Leaf Extract as Add-on to Statin 



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American Journal of Applied Science and Technology (ISSN: 2771-2745) 
 

 

Therapy in Hypercholesterolemic Type 2 Diabetic 
Patients: a Randomized Clinical Trial Saeed Kianbakht 1 

✓, Farzaneh Nabati 1, Behrooz Abasi 2 1. Medicinal 
Plants Research Center, Institute of Medicinal Plants, 
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doi:10.3390/antiox10091362 

Halyna Hachkova 1,*, Mariia Nagalievska 1, Zoriana 
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Anna Sokół-Łętowska 2, Elena Belonovskaya 3, 
Vyacheslav Buko 3, Nataliia Sybirna 1 Medicinal Plants 
Galega officinalis L. and Yacon Leaves as Potential 
Sources of Antidiabetic Drugs 

Ajami M, Seyfi M, Abdollah pouri Hosseini F, Naseri P, 
Velayati A, Mahmoudnia F, Zahedi M, Hajifaraji M. 
Effects of stevia on glycemic and lipid profile of type 2 
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Avicenna J Phytomed, 2020; 10 (2): 118-127. 

Journal of Clinical Pharmacology George B. Kudolo PhD 
Effect of 3-month intake of Ginkgo biloba extract (EGb 
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in people with insulin-independent diabetes mellitus. 

https://uz.wikipedia.org/wiki/Ginkgo 

Annayeva G.B. Medicinal properties of chicory and its 
role in the preparation of beverages. "Bulletin of 
Science" No4 (61) T.4 April 2023. 

https://www.asna.ru/car 

https://tea-kavkaz.ru/1-gornye-chai-i-travyanye-
napitki/celebnye-travyanye-sbory/diabefit-20-filtr-
paketov 

https://o-
zd.ru/catalog/popravit_zdorove/kapsuly_drazhzhe_ta
bletki/9760/ 

http://apteka999.uz/ru/catalog/2572-fitachay-
glyunorm-(zamona-rano) 


