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American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 06 PAGES: 45-53 

OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

Servi 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ABSTRACT 

Reducing perinatal morbidity and mortality is one of the main tasks of the maternal and child health care system. 

Congenital anomalies contribute significantly to these indicators and occupy leading positions in terms of prevalence. 

According to the World Health Organization, 25% of newborns are born with developmental defects. In light of this 

data, increasing the efficiency of early medical care and reducing growth and development-related disorders in 

newborns is crucial. Congenital anomalies of the digestive tract occupy a primary place, corresponding to 21.7%-25%. 

Currently, perinatal studies of the problem of mother and child with congenital digestive tract anomalies are 

considered separately, which is significant for perinatal diagnostics, the ability to predict congenital digestive tract 

anomalies, and determining tactics. This is of great importance for both pediatricians and surgeons. As a first step in 

  Research Article 

 

TYPES AND STRUCTURE OF SURGICAL DISEASES IN NEWBORNS 

ACCORDING TO DATA FROM A REGIONAL CENTER 
 

Submission Date: June 14, 2024, Accepted Date:  June 19, 2024,  

Published Date: June 24, 2024  

Crossref doi: https://doi.org/10.37547/ajbspi/Volume04Issue06-08 

 

 

Mavlyanov F.Sh. 
Samarkand State Medical University, Samarkand Regional Children's Multidisciplinary Medical Center, 

Samarkand, Uzbekistan 

 

Azizov M.K. 
Samarkand State Medical University, Samarkand Regional Children's Multidisciplinary Medical Center, 

Samarkand, Uzbekistan 

 

Tursunov S.E. 
Samarkand State Medical University, Samarkand Regional Children's Multidisciplinary Medical Center, 

Samarkand, Uzbekistan 

 

Mavlyanov Sh.K. 
Samarkand State Medical University, Samarkand Regional Children's Multidisciplinary Medical Center, 

Samarkand, Uzbekistan 

 

 

 

 

Journal Website: 

https://theusajournals.

com/index.php/ajbspi 

Copyright: Original 

content from this work 

may be used under the 

terms of the creative 

commons attributes 

4.0 licence. 

 

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Volume 04 Issue 06-2024 46 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 06 PAGES: 45-53 

OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

Servi 

creating a system for assessing and improving medical services provided to the younger generation, it is important to 

optimize medical care for newborns with surgical diseases. 

KEYWORDS 

Perinatal studies, indicators and occupy leading positions, determining tactics. 

INTRODUCTION

To study the types and frequency of nosological forms 

of surgical diseases in newborns that required surgical 

treatment within the first day of life. 

METHODS 

The material for the study was a retrospective analysis 

of official data from annual reports of the heads of 

neonatology and newborn surgery departments of the 

Samarkand Regional Children's Multidisciplinary 

Medical Center for the period from 2017 to 2022. The 

study was multi-stage. The program and methodology 

of the study are presented in Table 1. 

Table 1. 

Program and Methodology of the Study 

Stages Work Content 

Observation 

Objects and 

Research Methods 

Information 

Sources and 

Observation 

Volume 

I 

Study of the 

morbidity level of 

surgical pathology 

among newborns 

hospitalized 

Neonatology and 

neonatal surgery 

patients 

Official data from 

annual reports 

(2017-2022) 

II 

Clinical and 

statistical 

characteristics of 

gastrointestinal 

surgical diseases in 

hospitalized 

newborns 

Neonatal surgery 

and neonatology 

ICU patients 

Retrospective and 

prospective 

controlled study of 

diagnosis and 

treatment results 

(2017-2022) 

 

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Volume 04 Issue 06-2024 47 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 06 PAGES: 45-53 

OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

Servi 

The level of surgical pathology among newborns was 

analyzed at the first stage of the study using 

hospitalization data. 

During the second stage of the analysis, the results of 

diagnosis and treatment were examined. As a result, 

the clinical-statistical characteristics of congenital 

gastrointestinal surgical diseases in 335 children, which 

led to hospitalization, were identified. 

RESULTS AND DISCUSSION 

Based on the statistical data registry from annual 

reports (2017-2022), 14,994 newborns were 

hospitalized at the Samarkand Regional Children's 

Multidisciplinary Medical Center, with 2,012 infants 

having surgical pathology (Table 2). 

Table 2: 

Number of Newborns with Surgical Diseases (2017-2022) 

Hospitalization 

Period 

Number of the children 

Other Pathologies 
Urogenital System 

Pathology 
Total 

2017 2281(91,6%) 209 (8.4%) 2490 (100%) 

2018 2288 (87.5%) 326 (12.5%) 2614 (100%) 

2019 2129 (82.9%) 438 (17.1%) 2567 (100%) 

2020 1703 (81.7%) 380 (18.3%) 2083 (100%) 

2021 2026 (77.7%) 580 (22.3%) 2606 (100%) 

2022 2346 (89.1%) 288 (10.9%) 2634 (100%) 

Total 12982 (86.6%) 2012 (13.4%) 14994 (100%) 

 

It is evident that the actual incidence of surgical 

diseases might be significantly higher than the 

registered statistical data. The increase in the level of 

medical care and the rise in morbidity are not only due 

to an increase in the number of diseases among 

newborns but also due to the improvement in the 

quality of medical care provided. The study showed 

that surgical pathology among infants and young 

children (up to 1 year old) averaged 13.4%. 

As the studies indicated, congenital intestinal 

obstruction ranked first in the structure of morbidity 

based on hospitalization data (42.1%), followed by 

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Volume 04 Issue 06-2024 48 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 06 PAGES: 45-53 

OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

Servi 

anorectal malformations (21.5%). A significant number 

of newborns had anterior abdominal wall defects and 

necrotizing enterocolitis, accounting for 11.9% and 10%, 

respectively (Table 3). 

Table 3: 

Nosological Forms of Gastrointestinal Surgical Diseases in Newborns 

Final Diagnosis Number of Infants 

Jejunal Atresia 8 

Ileal Atresia 42 

Small Bowel Atresia, Necrosis, Perforation, Peritonitis 5 

Cecal Atresia 1 

Small Bowel Membrane 3 

Duodenal Atresia 4 

Aberrant Duodenal Vessel 1 

Duodenal Membrane 10 

Ladd's Syndrome 25 

Annular Pancreas 18 

Meconium Ileus 3 

Embryonic Adhesions of the Duodenum 6 

Hirschsprung's Disease, Acute Form 16 

Necrotizing Enterocolitis 34 

Lower ARM (Anorectal Malformation) 40 

Upper ARM 31 

Esophageal Atresia 25 

Congenital Pyloric Stenosis 23 

Gastroschisis 8 

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Volume 04 Issue 06-2024 49 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 06 PAGES: 45-53 

OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

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Omphalocele 32 

Total 335 

 

Among the infants, there were 217 boys and 118 girls. 

As shown in the table below (Table 4), the number of 

patients from rural areas significantly exceeded those 

from urban areas. The majority of children (79.1%) had 

a normal body weight at the time of hospitalization. By 

gestational age at birth, there were 251 full-term 

infants, 59 preterm, and 22 post-term newborns. 

Table 4: 

General Characteristics of Patients 

Gender Total 

Boys 217 (64.8%) 
335 (100%) 

Girls 118 (35.2%) 

Address 

City 9 
335 (100%) 

Village 326 

Weight at Admission 

Normal 265 (79.1%) 

335 (100%) Low 68 (20.3%) 

Very Low 2 (0.6%) 

Gestational Age 

Full-term 251 335 (100%) 

 

The study of the routing of newborns with surgical 

diseases found that the vast majority of patients 

(76.4%) were rehospitalized from the maternity 

hospital. Within the first 48 hours of birth, 194 infants 

were hospitalized. 141 patients were hospitalized more 

than 48 hours after birth. 83.6% of the children 

underwent surgery within 24 hours of admission (Table 

5).

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Volume 04 Issue 06-2024 50 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 06 PAGES: 45-53 

OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

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Table 5 

Routing of Hospitalized Newborns 

Pathways to Hospitalization Number of Patients Percentage 

Rehospitalization from Maternity Ward 256 76.4% 

From Home 79 23.6% 

Total 335 100% 

Time from Birth to Hospitalization Number of Patients Percentage 

Within 48 Hours 194 57.9% 

More than 48 Hours 141 42.1% 

Total 335 100% 

Time from Hospitalization to Surgery Number of Patients Percentage 

Within 24 Hours 280 83.6% 

More than 24 Hours 55 16.4% 

Total 335 100% 

 

Surgical treatment was performed on 333 newborns. 

Surgery was not conducted on 2 patients due to 

parental refusal of the proposed treatment. Surgical 

intervention was performed on 194 newborns within 

48 hours from birth. The remaining infants underwent 

surgery more than 48 hours after birth. From the time 

of admission to surgery, 83.6% of the patients were 

operated on within 24 hours, and 55 newborns were 

operated on later. 

The following surgical procedures were performed on 

the 333 newborns (Table 6). 

 

Table 6 

Types of Operations Performed on Newborns with Congenital Intestinal 

Obstruction 

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Volume 04 Issue 06-2024 51 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 06 PAGES: 45-53 

OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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Operation Name 
Number of 

Patients 

Abdominal Drainage 13 

Membrane Resection of the Duodenum, Naso-Intestinal 

Intubation 
7 

Membrane Resection of the Small Intestine 3 

Partial Resection of the Small Intestine, T-shaped Ileal-Ileal 

Anastomosis 
19 

Duodeno-Duodenal Anastomosis, Naso-Intestinal Intubation 26 

Ladd's Operation 25 

Partial Resection of the Small Intestine, Ileal-Ascendostomy 

Anastomosis 
1 

Embryonic Adhesions of the Duodenum, Naso-Intestinal 

Intubation 
6 

Laparotomy, Jejuno-Jejunal Anastomosis, Naso-Intestinal 

Intubation 
3 

Laparotomy, Colostomy 7 

Perineal proctoplasty 42 

Left-sided Maydl colostomy 42 

Laparotomy, cecal resection, ileostomy 1 

Partial resection of small intestine, ileostomy 42 

Esophago-esophagostomy 25 

Laparotomy, pyloromyotomy 23 

Gastroschisis repair 7 

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Volume 04 Issue 06-2024 52 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 06 PAGES: 45-53 

OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

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Omphalocele repair 32 

Laparotomy, gastric perforation closure 5 

Laparotomy, small intestine perforation closure, 

appendicostomy 
2 

Laparotomy, cecostomy 1 

Resection of embryonic adhesions in the abdominal cavity 1 

Total 333 

Naso-intestinal intubation 45 

Ileostomies 45 

Colostomies 50 

T-shaped anastomoses 20 

 

CONCLUSIONS 

Based on the conducted research, surgical diseases 

among pathological conditions in newborns constitute 

13.4%. In our view, this frequency represents a 

significant medical and social issue that requires 

increased attention from the medical system at all 

levels. 

A clear classification and detailed study of the 

epidemiological features of these pathologies in 

different regions and population groups are essential 

steps in optimizing medical care, developing effective 

preventive measures, and rationally allocating 

healthcare resources. Only a comprehensive approach 

that considers the epidemiological, clinical, and social 

aspects of this problem will achieve significant 

progress in the field of neonatal surgery. 

The established increase in the incidence of surgical 

diseases in newborns necessitates the justification of 

modern, cost-effective approaches to organizing 

medical care, treatment methods, and rehabilitation of 

patients. The large number and variety of surgical 

operations on the digestive system performed on 

newborns in the first days of life prompt the search for 

ways to improve their outcomes. 

REFERENCES 

1. Kagan, A. V. (2006). **Improvement of Surgical 

Care for Newborns in a Large City** (Doctoral 

dissertation). Saint Petersburg, 261 pages. 

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Volume 04 Issue 06-2024 53 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 06 PAGES: 45-53 

OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

Servi 

2. Mavlyanov, F., Mavlyanov, Sh., Tursunov, S., & 

Baratov, U. (2021). **Ways to Improve the 

Outcomes of Treatment in Children with 

Congenital Intestinal Obstruction**. Pediatric 

Surgery, 25(S1), 51. 

3. Isakov, Y. F. (Ed.). (2004). **Surgical Diseases of 

Childhood** (Vol. 1). Moscow: Medical Publishing, 

302 pages. 

4. Bethell, G. S., Long, A. M., Knight, M., & Hall, N. J. 

(2020). **Congenital Duodenal Obstruction in the 

UK: A Population-Based Study**. Archives of 

Disease in Childhood: Fetal and Neonatal Edition, 

105, F178-F183. 

5. Peng, Y. F., Zheng, H. Q., Zhang, H., He, Q. M., 

Wang, Z., & Zhong, W., et al. (2019). **Comparison 

of Outcomes Following Three Surgical Techniques 

for Patients with Severe Jejunoileal Atresia**. 

Gastroenterology Report (Oxford), 7, 444-448. 

6. Laurens, D. E., Backes, M., de Jonge, W. J., van 

Heurn, E. L. W., & Derikx, J. P. M. (2022). 

**Treatment of Jejunoileal Atresia by Primary 

Anastomosis or Enterostomy: Double the 

Operations, Double the Risk of Complications**. 

Journal of Pediatric Surgery, 57(9), 49-54. 

7. Kinlin, C., & Shawyer, A. C. (2017). **The Surgical 

Management of Malrotation: A Canadian 

Association of Pediatric Surgeons Survey**. 

Journal of Pediatric Surgery, 52, 853-858. 

8. Saberi, R. A., Gilna, G. P., Slavin, B. V., Perez, E. A., 

Sola, J. E., & Thorson, C. M. (2022). **Outcomes for 

Ladd's Procedure: Does Approach Matter?** 

Journal of Pediatric Surgery, 57(1), 141-146. 

 

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