







































Volume 04 Issue 01-2024 93 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 01 PAGES: 93-97 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 6.534) 
OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

Servi 

 

 

 

 

 

 

 

 

 

ABSTRACT 

Hypersensitivity of hard dental tissues after whitening is one of the most common pathological conditions that create 

discomfort and have a negative impact on the functional state of the oral cavity. For treatment, 66 patients aged 30–

40 years with at least 20–25 natural teeth with a preserved crown and without severe concomitant pathology were 

selected, with complaints of hyperesthesia of the teeth after professional whitening. Over the course of 6 months, 

using clinical methods and subjective sensations of patients, the severity of hyperesthesia after treatment with various 

desensitizers was compared . The high efficiency of Telio CS Desensitizer in the treatment and prevention of 

hyperesthesia of hard dental tissues was revealed. 

KEYWORDS 

Hyperesthesia, teeth whitening, desensitizer. 

INTRODUCTION

Purpose of the study: comparative assessment of the 

clinical effectiveness of various desensitizers in the 

prevention and treatment of dental hyperesthesia 

after whitening. 

  Research Article 

 

COMPARISON OF THE EFFECTIVENESS OF TREATMENT FOR DENTAL 

HYPERESTHESIA 
 

Submission Date: January 21, 2024, Accepted Date:  January 26, 2024,  

Published Date: January 31, 2024  

Crossref doi: https://doi.org/10.37547/ajbspi/Volume04Issue01-14 

 

 

Daminova Sh.B. 
Tashkent State Dental Institute, Uzbekistan 

 

Khasanov E.T. 
Tashkent State Dental Institute, Uzbekistan 

Journal Website: 

https://theusajournals.

com/index.php/ajbspi 

Copyright: Original 

content from this work 

may be used under the 

terms of the creative 

commons attributes 

4.0 licence. 

 

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Volume 04 Issue 01-2024 94 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 01 PAGES: 93-97 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 6.534) 
OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

Servi 

Beautiful and attractive teeth, as a sign of social well-

being and beauty, are becoming increasingly in 

demand for practical dentistry in all social and age 

groups of the population. Scientific research 

conducted in this area has shown that people with 

dental discoloration often experience certain 

problems with social adaptation and are often subject 

to some kind of discrimination in society. This leads to 

the demand for both the whitening procedure itself 

and the range of constantly improved whitening 

products and techniques offered in dental clinics. 

Increased sensitivity of hard dental tissues, often 

observed after whitening, is one of the most common 

pathological conditions that create discomfort and 

have a negative impact on the functional state of the 

mouth. According to some data, hyperesthesia affects 

from 15 to 68% of the population, and the causes of its 

occurrence are quite numerous. Increased sensitivity 

also manifests itself in carious and non-carious lesions, 

various damage to the enamel, in particular the 

presence of cracks, as well as after preparation of hard 

dental tissues. As stated earlier, increased sensitivity 

also occurs after professional teeth whitening. The 

high demand for this type of dental care also requires 

a timely increase in the effectiveness of treatment and 

prevention of dental hyperesthesia]. Thus, despite the 

achievements of dental materials science in the 

development of new means for the treatment and 

prevention of dental hypersensitivity (based on 

important micro- and macroelements, calcium, 

fluorides, as well as modern desensitizers) that 

improve the quality of life of the population, there is 

still a need for further study and comparative 

assessment of the clinical effectiveness of modern 

drugs, and on this basis - their optimal individual choice 

for each clinical situation. 

MATERIALS AND METHODS 

To determine the causes of discoloration , we 

interviewed 66 patients aged 30 to 40 years who 

wanted to improve the color aesthetics of their teeth 

and change their color using professional chemical 

whitening. In 35% of respondents, staining of the 

surface of the crowns of vital teeth is caused by 

ingestion of foods rich in dyes. Thus, almost 60% of 

respondents regularly drink 2-3 cups of coffee a day, 

and almost 15% of respondents drink carbonated drinks 

with dyes. One of the main exogenous factors 

contributing to the development of dental 

discoloration is smoking. A change in the natural 

appearance of tooth crowns was most often found in 

unsatisfactory hygienic condition of the oral cavity in 

combination with abundant deposition of smoker’s 

plaque with subsequent pigmentation of the vestibular 

and oral surfaces of the hard tissues of the teeth. A 

relatively large proportion of respondents indicated a 

low level of effectiveness of previously performed 

whitening procedures. 

Today, there are many desensitizers from various 

manufacturers on the domestic market, operating on 

the basis of one or a combination of several 

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Volume 04 Issue 01-2024 95 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 01 PAGES: 93-97 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 6.534) 
OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

Servi 

mechanisms. Many desensitizers are based on 

modified dentine primer hydroxyethyl methacrylate 

(HEMA). Additionally, drugs are introduced into it that 

cause sealing of the dentinal tubules, fluorides and 

antibacterial components in various combinations. To 

achieve this goal, the materials of scientific and medical 

resources on the subject under consideration were 

studied and analyzed due to the wide variety of 

combinations of drugs used to reduce the 

hypersensitivity of hard dental tissues. And based on 

the results obtained, drugs were selected to assess the 

clinical effectiveness of their use. This study involved 

66 patients aged 30-40 years, with at least 20-25 

natural teeth with a preserved crown and without 

severe comorbidity, with complaints of hyperesthesia 

of the teeth after professional whitening. In the first 

group of patients, the drug was GC " Tooth Mousse " 

(Japan). The drug is a water-soluble cream containing 

the Recaldent complex , consisting of CPP (casein 

phosphopeptide ) and ACP (amorphous calcium 

phosphate), which has the ability to bind a large 

amount of calcium and phosphate ions, keeping them 

in an amorphous non - crystalline state and provides 

high adhesion of the drug to the hard tissues of the 

tooth, pellicle, plaque components and soft tissues of 

the oral cavity, thereby providing a prolonged effect of 

the drug. Paste applications were carried out in a 

clinical setting in accordance with the manufacturer's 

instructions for 3 minutes. Patients were advised to 

refrain from eating for 30 minutes. Each patient was 

instructed on the use of this drug at home . The drug 

was applied 2 times a day with a dry finger or applicator 

after brushing the teeth for 5 minutes. For better 

penetration of the drug into the interdental spaces, it 

was recommended to use floss . During the procedure, 

it was not recommended to spit and swallow saliva. 

Additional rinsing of the oral cavity was not required. 

For the next 30 minutes, you should not drink or eat. 

Control examinations of patients were carried out at 

the beginning of the study (initial examination) and 

during the period of application of the remineralizing 

drug - after 1 and 2 weeks. The obtained data were 

entered into a special survey card. Gluma was chosen 

as the basis for the treatment of patients in the second 

group. Desensitizer ( Heraues Kulzer , Germany ) . 

Gluma Desensitizer is a product containing HEMA ( 

hydroxyethyl ) methacrylate , glutaraldehyde and 

distilled water. The mechanism of action of this drug is 

that it coagulates the proteins of the dentinal fluid 

inside the dentinal tubules, forming transverse 

partitions that block the movement of dentinal fluid, 

which reduces the sensitivity of the dentin. Due to the 

presence of HEMA in the composition, its penetration 

depth increases to 200 microns (0.2 mm). Paste 

applications were carried out in a clinical setting in 

accordance with the manufacturer's instructions. To 

begin, the dentin to be treated was cleaned under local 

anesthesia and then rinsed with water. The mucosa 

was protected with a rubber dam. Then, a small 

amount of GLUMA® Desensitizer needed for 

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Volume 04 Issue 01-2024 96 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 01 PAGES: 93-97 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 6.534) 
OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

Servi 

treatment was applied to the treated dentin surface 

with a brush and left for 30-60 seconds. During this 

time, we carefully monitored that GLUMA® 

Desensitizer did not drip from the application area. 

After that, the surface was carefully dried with a jet of 

air until the liquid film disappeared and the surface 

stopped shining, then washed with plenty of water. 

Control examinations of patients were carried out at 

the beginning of the study (initial examination) and 

during the period of application of the remineralizing 

drug - after 1 and 2 weeks. 

The results of the study showed that patients in the 

first group, when treated with water-based 

remineralizing paste GC ToothMousse , had comments 

about the pleasant taste and smell, as well as the 

convenience and comfort of using this paste. After 

using it, the feeling of fresh breath remained for a long 

time. During the study period, according to control 

dental examinations, there were no cases of local 

irritating or allergenic effects of the paste on the oral 

mucosa. Thus, regular use of a remineralizing drug 

contributed to the fact that in 22 patients (88%) 

complaints about tooth sensitivity disappeared, and in 

3 (12%) the symptoms of this pathology decreased. In 

patients of the second group, on whom GLUMA® 

Desensitizer was used , before treatment, all patients 

were clinically determined to have a noticeable pain 

reaction to irritants. After treatment, dental 

hypersensitivity disappeared in 20 (80%) patients, and 

decreased in only 5 (20%) patients. We also found that 

with repeated local application of GLUMA® 

Desensitizer , the therapeutic effect is enhanced. The 

results of treatment of patients were assessed using 

basic (questioning, examination) and additional ( 

thermal diagnostics ) research methods. 

Conclusion 

Thus, our research has shown that the most effective 

remedy for reducing tooth sensitivity was the water-

based remineralizing paste GC ToothMousse . 

REFERENCES 

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Volume 04 Issue 01-2024 97 

                 

 
 

   
  
 

American Journal Of Biomedical Science & Pharmaceutical Innovation    
(ISSN – 2771-2753) 
VOLUME 04 ISSUE 01 PAGES: 93-97 

SJIF IMPACT FACTOR (2021: 5. 705) (2022: 5. 705) (2023: 6.534) 
OCLC – 1121105677     

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Publisher: Oscar Publishing Services 

Servi 

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