id	sid	tid	token	lemma	pos
ajbspi-122364	1	1	american	american	PROPN
ajbspi-122364	1	2	journal	journal	PROPN
ajbspi-122364	1	3	of	of	ADP
ajbspi-122364	1	4	biomedical	biomedical	PROPN
ajbspi-122364	1	5	science	science	PROPN
ajbspi-122364	1	6	&	&	CCONJ
ajbspi-122364	1	7	pharmaceutical	pharmaceutical	PROPN
ajbspi-122364	1	8	innovation	innovation	NOUN
ajbspi-122364	1	9	25	25	NUM
ajbspi-122364	1	10	https://theusajournals.com/index.php/ajbspi	https://theusajournals.com/index.php/ajbspi	NOUN
ajbspi-122364	1	11	volume	volume	NOUN
ajbspi-122364	1	12	vol.05	vol.05	NOUN
ajbspi-122364	1	13	issue06	issue06	PROPN
ajbspi-122364	1	14	2025	2025	NUM
ajbspi-122364	1	15	page	page	NOUN
ajbspi-122364	1	16	no	no	INTJ
ajbspi-122364	1	17	.	.	NOUN
ajbspi-122364	2	1	25	25	NUM
ajbspi-122364	2	2	-	-	SYM
ajbspi-122364	2	3	27	27	NUM
ajbspi-122364	2	4	doi	doi	NOUN
ajbspi-122364	2	5	10.37547	10.37547	NUM
ajbspi-122364	2	6	/	/	SYM
ajbspi-122364	2	7	ajbspi	ajbspi	NOUN
ajbspi-122364	2	8	/	/	SYM
ajbspi-122364	2	9	volume05issue06	volume05issue06	NOUN
ajbspi-122364	2	10	-	-	PUNCT
ajbspi-122364	2	11	06	06	NUM
ajbspi-122364	2	12	blood	blood	NOUN
ajbspi-122364	2	13	-	-	PUNCT
ajbspi-122364	2	14	brain	brain	NOUN
ajbspi-122364	2	15	barrier	barrier	NOUN
ajbspi-122364	2	16	:	:	PUNCT
ajbspi-122364	2	17	structure	structure	NOUN
ajbspi-122364	2	18	,	,	PUNCT
ajbspi-122364	2	19	function	function	NOUN
ajbspi-122364	2	20	and	and	CCONJ
ajbspi-122364	2	21	neurological	neurological	ADJ
ajbspi-122364	2	22	consequences	consequence	NOUN
ajbspi-122364	2	23	of	of	ADP
ajbspi-122364	2	24	disruption	disruption	NOUN
ajbspi-122364	2	25	:	:	PUNCT
ajbspi-122364	2	26	role	role	NOUN
ajbspi-122364	2	27	in	in	ADP
ajbspi-122364	2	28	brain	brain	NOUN
ajbspi-122364	2	29	protection	protection	NOUN
ajbspi-122364	2	30	and	and	CCONJ
ajbspi-122364	2	31	maintenance	maintenance	NOUN
ajbspi-122364	2	32	of	of	ADP
ajbspi-122364	2	33	homeostasis	homeostasis	NOUN
ajbspi-122364	2	34	.	.	PUNCT
ajbspi-122364	2	35	disturbances	disturbance	NOUN
ajbspi-122364	2	36	in	in	ADP
ajbspi-122364	2	37	strokes	stroke	NOUN
ajbspi-122364	2	38	,	,	PUNCT
ajbspi-122364	2	39	neuroinfections	neuroinfection	NOUN
ajbspi-122364	2	40	,	,	PUNCT
ajbspi-122364	2	41	neurodegeneration	neurodegeneration	NOUN
ajbspi-122364	2	42	,	,	PUNCT
ajbspi-122364	2	43	tumors	tumor	NOUN
ajbspi-122364	2	44	petrova	petrova	PROPN
ajbspi-122364	2	45	yurita	yurita	PROPN
ajbspi-122364	2	46	yurievna	yurievna	PROPN
ajbspi-122364	2	47	assistant	assistant	PROPN
ajbspi-122364	2	48	professor	professor	NOUN
ajbspi-122364	2	49	,	,	PUNCT
ajbspi-122364	2	50	department	department	NOUN
ajbspi-122364	2	51	of	of	ADP
ajbspi-122364	2	52	biomedical	biomedical	ADJ
ajbspi-122364	2	53	sciences	sciences	PROPN
ajbspi-122364	2	54	,	,	PUNCT
ajbspi-122364	2	55	emu	emu	PROPN
ajbspi-122364	2	56	university	university	PROPN
ajbspi-122364	2	57	,	,	PUNCT
ajbspi-122364	2	58	uzbekistan	uzbekistan	PROPN
ajbspi-122364	2	59	received	receive	VERB
ajbspi-122364	2	60	:	:	PUNCT
ajbspi-122364	2	61	17	17	NUM
ajbspi-122364	2	62	april	april	PROPN
ajbspi-122364	2	63	2025	2025	NUM
ajbspi-122364	2	64	;	;	PUNCT
ajbspi-122364	2	65	accepted	accept	VERB
ajbspi-122364	2	66	:	:	PUNCT
ajbspi-122364	2	67	24	24	NUM
ajbspi-122364	2	68	may	may	PROPN
ajbspi-122364	2	69	2025	2025	NUM
ajbspi-122364	2	70	;	;	PUNCT
ajbspi-122364	2	71	published	publish	VERB
ajbspi-122364	2	72	:	:	PUNCT
ajbspi-122364	2	73	30	30	NUM
ajbspi-122364	2	74	june	june	PROPN
ajbspi-122364	2	75	2025	2025	NUM
ajbspi-122364	2	76	abstract	abstract	NOUN
ajbspi-122364	2	77	:	:	PUNCT
ajbspi-122364	2	78	the	the	DET
ajbspi-122364	2	79	blood	blood	NOUN
ajbspi-122364	2	80	-	-	PUNCT
ajbspi-122364	2	81	brain	brain	NOUN
ajbspi-122364	2	82	barrier	barrier	NOUN
ajbspi-122364	2	83	(	(	PUNCT
ajbspi-122364	2	84	bbb	bbb	NOUN
ajbspi-122364	2	85	)	)	PUNCT
ajbspi-122364	2	86	is	be	AUX
ajbspi-122364	2	87	a	a	DET
ajbspi-122364	2	88	complex	complex	ADJ
ajbspi-122364	2	89	morphofunctional	morphofunctional	ADJ
ajbspi-122364	2	90	system	system	NOUN
ajbspi-122364	2	91	that	that	PRON
ajbspi-122364	2	92	ensures	ensure	VERB
ajbspi-122364	2	93	selective	selective	ADJ
ajbspi-122364	2	94	permeability	permeability	NOUN
ajbspi-122364	2	95	between	between	ADP
ajbspi-122364	2	96	the	the	DET
ajbspi-122364	2	97	bloodstream	bloodstream	NOUN
ajbspi-122364	2	98	and	and	CCONJ
ajbspi-122364	2	99	tissues	tissue	NOUN
ajbspi-122364	2	100	of	of	ADP
ajbspi-122364	2	101	the	the	DET
ajbspi-122364	2	102	central	central	ADJ
ajbspi-122364	2	103	nervous	nervous	ADJ
ajbspi-122364	2	104	system	system	NOUN
ajbspi-122364	2	105	.	.	PUNCT
ajbspi-122364	3	1	this	this	DET
ajbspi-122364	3	2	article	article	NOUN
ajbspi-122364	3	3	discusses	discuss	VERB
ajbspi-122364	3	4	the	the	DET
ajbspi-122364	3	5	anatomical	anatomical	ADJ
ajbspi-122364	3	6	and	and	CCONJ
ajbspi-122364	3	7	histological	histological	ADJ
ajbspi-122364	3	8	structure	structure	NOUN
ajbspi-122364	3	9	of	of	ADP
ajbspi-122364	3	10	the	the	DET
ajbspi-122364	3	11	bbb	bbb	PROPN
ajbspi-122364	3	12	,	,	PUNCT
ajbspi-122364	3	13	its	its	PRON
ajbspi-122364	3	14	key	key	ADJ
ajbspi-122364	3	15	functions	function	NOUN
ajbspi-122364	3	16	in	in	ADP
ajbspi-122364	3	17	protecting	protect	VERB
ajbspi-122364	3	18	the	the	DET
ajbspi-122364	3	19	brain	brain	NOUN
ajbspi-122364	3	20	and	and	CCONJ
ajbspi-122364	3	21	maintaining	maintain	VERB
ajbspi-122364	3	22	neuronal	neuronal	ADJ
ajbspi-122364	3	23	homeostasis	homeostasis	NOUN
ajbspi-122364	3	24	.	.	PUNCT
ajbspi-122364	4	1	particular	particular	ADJ
ajbspi-122364	4	2	attention	attention	NOUN
ajbspi-122364	4	3	is	be	AUX
ajbspi-122364	4	4	paid	pay	VERB
ajbspi-122364	4	5	to	to	ADP
ajbspi-122364	4	6	the	the	DET
ajbspi-122364	4	7	mechanisms	mechanism	NOUN
ajbspi-122364	4	8	of	of	ADP
ajbspi-122364	4	9	barrier	barrier	NOUN
ajbspi-122364	4	10	function	function	NOUN
ajbspi-122364	4	11	impairment	impairment	NOUN
ajbspi-122364	4	12	in	in	ADP
ajbspi-122364	4	13	various	various	ADJ
ajbspi-122364	4	14	pathological	pathological	ADJ
ajbspi-122364	4	15	conditions	condition	NOUN
ajbspi-122364	4	16	strokes	stroke	NOUN
ajbspi-122364	4	17	,	,	PUNCT
ajbspi-122364	4	18	neuroinfections	neuroinfection	NOUN
ajbspi-122364	4	19	,	,	PUNCT
ajbspi-122364	4	20	neurodegenerative	neurodegenerative	ADJ
ajbspi-122364	4	21	diseases	disease	NOUN
ajbspi-122364	4	22	and	and	CCONJ
ajbspi-122364	4	23	brain	brain	NOUN
ajbspi-122364	4	24	tumors	tumor	NOUN
ajbspi-122364	4	25	.	.	PUNCT
ajbspi-122364	5	1	the	the	DET
ajbspi-122364	5	2	consequences	consequence	NOUN
ajbspi-122364	5	3	of	of	ADP
ajbspi-122364	5	4	bbb	bbb	PROPN
ajbspi-122364	5	5	dysfunction	dysfunction	NOUN
ajbspi-122364	5	6	and	and	CCONJ
ajbspi-122364	5	7	modern	modern	ADJ
ajbspi-122364	5	8	approaches	approach	NOUN
ajbspi-122364	5	9	to	to	ADP
ajbspi-122364	5	10	diagnostics	diagnostic	NOUN
ajbspi-122364	5	11	and	and	CCONJ
ajbspi-122364	5	12	therapy	therapy	NOUN
ajbspi-122364	5	13	,	,	PUNCT
ajbspi-122364	5	14	including	include	VERB
ajbspi-122364	5	15	pharmacological	pharmacological	ADJ
ajbspi-122364	5	16	modulation	modulation	NOUN
ajbspi-122364	5	17	and	and	CCONJ
ajbspi-122364	5	18	targeted	target	VERB
ajbspi-122364	5	19	drug	drug	NOUN
ajbspi-122364	5	20	delivery	delivery	NOUN
ajbspi-122364	5	21	technologies	technology	NOUN
ajbspi-122364	5	22	are	be	AUX
ajbspi-122364	5	23	analyzed	analyze	VERB
ajbspi-122364	5	24	.	.	PUNCT
ajbspi-122364	6	1	the	the	DET
ajbspi-122364	6	2	presented	present	VERB
ajbspi-122364	6	3	material	material	NOUN
ajbspi-122364	6	4	emphasizes	emphasize	VERB
ajbspi-122364	6	5	the	the	DET
ajbspi-122364	6	6	importance	importance	NOUN
ajbspi-122364	6	7	of	of	ADP
ajbspi-122364	6	8	maintaining	maintain	VERB
ajbspi-122364	6	9	the	the	DET
ajbspi-122364	6	10	integrity	integrity	NOUN
ajbspi-122364	6	11	of	of	ADP
ajbspi-122364	6	12	the	the	DET
ajbspi-122364	6	13	bbb	bbb	PROPN
ajbspi-122364	6	14	for	for	ADP
ajbspi-122364	6	15	neuroprotection	neuroprotection	NOUN
ajbspi-122364	6	16	and	and	CCONJ
ajbspi-122364	6	17	treatment	treatment	NOUN
ajbspi-122364	6	18	of	of	ADP
ajbspi-122364	6	19	a	a	DET
ajbspi-122364	6	20	wide	wide	ADJ
ajbspi-122364	6	21	range	range	NOUN
ajbspi-122364	6	22	of	of	ADP
ajbspi-122364	6	23	neurological	neurological	ADJ
ajbspi-122364	6	24	disorders	disorder	NOUN
ajbspi-122364	6	25	.	.	PUNCT
ajbspi-122364	7	1	keywords	keyword	NOUN
ajbspi-122364	7	2	:	:	PUNCT
ajbspi-122364	7	3	blood	blood	NOUN
ajbspi-122364	7	4	-	-	PUNCT
ajbspi-122364	7	5	brain	brain	NOUN
ajbspi-122364	7	6	barrier	barrier	NOUN
ajbspi-122364	7	7	,	,	PUNCT
ajbspi-122364	7	8	neurohomeostasis	neurohomeostasis	NOUN
ajbspi-122364	7	9	,	,	PUNCT
ajbspi-122364	7	10	permeability	permeability	NOUN
ajbspi-122364	7	11	,	,	PUNCT
ajbspi-122364	7	12	stroke	stroke	NOUN
ajbspi-122364	7	13	,	,	PUNCT
ajbspi-122364	7	14	neuroinfections	neuroinfection	NOUN
ajbspi-122364	7	15	,	,	PUNCT
ajbspi-122364	7	16	neurodegenerative	neurodegenerative	ADJ
ajbspi-122364	7	17	diseases	disease	NOUN
ajbspi-122364	7	18	,	,	PUNCT
ajbspi-122364	7	19	brain	brain	NOUN
ajbspi-122364	7	20	tumors	tumor	NOUN
ajbspi-122364	7	21	,	,	PUNCT
ajbspi-122364	7	22	cerebral	cerebral	ADJ
ajbspi-122364	7	23	edema	edema	NOUN
ajbspi-122364	7	24	,	,	PUNCT
ajbspi-122364	7	25	tight	tight	ADJ
ajbspi-122364	7	26	junctions	junction	NOUN
ajbspi-122364	7	27	,	,	PUNCT
ajbspi-122364	7	28	neuroinflammation	neuroinflammation	NOUN
ajbspi-122364	7	29	.	.	PUNCT
ajbspi-122364	8	1	introduction	introduction	NOUN
ajbspi-122364	8	2	:	:	PUNCT
ajbspi-122364	8	3	the	the	DET
ajbspi-122364	8	4	human	human	ADJ
ajbspi-122364	8	5	central	central	ADJ
ajbspi-122364	8	6	nervous	nervous	ADJ
ajbspi-122364	8	7	system	system	NOUN
ajbspi-122364	8	8	(	(	PUNCT
ajbspi-122364	8	9	cns	cns	NOUN
ajbspi-122364	8	10	)	)	PUNCT
ajbspi-122364	8	11	is	be	AUX
ajbspi-122364	8	12	highly	highly	ADV
ajbspi-122364	8	13	sensitive	sensitive	ADJ
ajbspi-122364	8	14	to	to	ADP
ajbspi-122364	8	15	changes	change	NOUN
ajbspi-122364	8	16	in	in	ADP
ajbspi-122364	8	17	the	the	DET
ajbspi-122364	8	18	internal	internal	ADJ
ajbspi-122364	8	19	and	and	CCONJ
ajbspi-122364	8	20	external	external	ADJ
ajbspi-122364	8	21	environment	environment	NOUN
ajbspi-122364	8	22	,	,	PUNCT
ajbspi-122364	8	23	which	which	PRON
ajbspi-122364	8	24	necessitates	necessitate	VERB
ajbspi-122364	8	25	its	its	PRON
ajbspi-122364	8	26	reliable	reliable	ADJ
ajbspi-122364	8	27	protection	protection	NOUN
ajbspi-122364	8	28	.	.	PUNCT
ajbspi-122364	9	1	one	one	NUM
ajbspi-122364	9	2	of	of	ADP
ajbspi-122364	9	3	the	the	DET
ajbspi-122364	9	4	key	key	ADJ
ajbspi-122364	9	5	structures	structure	NOUN
ajbspi-122364	9	6	that	that	PRON
ajbspi-122364	9	7	ensures	ensure	VERB
ajbspi-122364	9	8	the	the	DET
ajbspi-122364	9	9	isolation	isolation	NOUN
ajbspi-122364	9	10	of	of	ADP
ajbspi-122364	9	11	the	the	DET
ajbspi-122364	9	12	brain	brain	NOUN
ajbspi-122364	9	13	from	from	ADP
ajbspi-122364	9	14	potentially	potentially	ADV
ajbspi-122364	9	15	harmful	harmful	ADJ
ajbspi-122364	9	16	substances	substance	NOUN
ajbspi-122364	9	17	circulating	circulate	VERB
ajbspi-122364	9	18	in	in	ADP
ajbspi-122364	9	19	the	the	DET
ajbspi-122364	9	20	systemic	systemic	ADJ
ajbspi-122364	9	21	bloodstream	bloodstream	NOUN
ajbspi-122364	9	22	is	be	AUX
ajbspi-122364	9	23	the	the	DET
ajbspi-122364	9	24	blood	blood	NOUN
ajbspi-122364	9	25	-	-	PUNCT
ajbspi-122364	9	26	brain	brain	NOUN
ajbspi-122364	9	27	barrier	barrier	NOUN
ajbspi-122364	9	28	(	(	PUNCT
ajbspi-122364	9	29	bbb	bbb	PROPN
ajbspi-122364	9	30	)	)	PUNCT
ajbspi-122364	9	31	.	.	PUNCT
ajbspi-122364	10	1	this	this	DET
ajbspi-122364	10	2	unique	unique	ADJ
ajbspi-122364	10	3	structure	structure	NOUN
ajbspi-122364	10	4	,	,	PUNCT
ajbspi-122364	10	5	formed	form	VERB
ajbspi-122364	10	6	by	by	ADP
ajbspi-122364	10	7	tight	tight	ADJ
ajbspi-122364	10	8	junctions	junction	NOUN
ajbspi-122364	10	9	of	of	ADP
ajbspi-122364	10	10	endothelial	endothelial	ADJ
ajbspi-122364	10	11	cells	cell	NOUN
ajbspi-122364	10	12	of	of	ADP
ajbspi-122364	10	13	brain	brain	NOUN
ajbspi-122364	10	14	capillaries	capillary	NOUN
ajbspi-122364	10	15	,	,	PUNCT
ajbspi-122364	10	16	pericytes	pericyte	NOUN
ajbspi-122364	10	17	,	,	PUNCT
ajbspi-122364	10	18	astrocytes	astrocyte	NOUN
ajbspi-122364	10	19	and	and	CCONJ
ajbspi-122364	10	20	the	the	DET
ajbspi-122364	10	21	basement	basement	NOUN
ajbspi-122364	10	22	membrane	membrane	NOUN
ajbspi-122364	10	23	,	,	PUNCT
ajbspi-122364	10	24	acts	act	VERB
ajbspi-122364	10	25	as	as	ADP
ajbspi-122364	10	26	a	a	DET
ajbspi-122364	10	27	selective	selective	ADJ
ajbspi-122364	10	28	filter	filter	NOUN
ajbspi-122364	10	29	and	and	CCONJ
ajbspi-122364	10	30	active	active	ADJ
ajbspi-122364	10	31	regulator	regulator	NOUN
ajbspi-122364	10	32	of	of	ADP
ajbspi-122364	10	33	exchange	exchange	NOUN
ajbspi-122364	10	34	between	between	ADP
ajbspi-122364	10	35	blood	blood	NOUN
ajbspi-122364	10	36	and	and	CCONJ
ajbspi-122364	10	37	nervous	nervous	ADJ
ajbspi-122364	10	38	tissue	tissue	NOUN
ajbspi-122364	10	39	.	.	PUNCT
ajbspi-122364	11	1	the	the	DET
ajbspi-122364	11	2	bbb	bbb	PROPN
ajbspi-122364	11	3	not	not	PART
ajbspi-122364	11	4	only	only	ADV
ajbspi-122364	11	5	prevents	prevent	VERB
ajbspi-122364	11	6	the	the	DET
ajbspi-122364	11	7	penetration	penetration	NOUN
ajbspi-122364	11	8	of	of	ADP
ajbspi-122364	11	9	toxins	toxin	NOUN
ajbspi-122364	11	10	,	,	PUNCT
ajbspi-122364	11	11	pathogens	pathogen	NOUN
ajbspi-122364	11	12	and	and	CCONJ
ajbspi-122364	11	13	immune	immune	ADJ
ajbspi-122364	11	14	cells	cell	NOUN
ajbspi-122364	11	15	into	into	ADP
ajbspi-122364	11	16	the	the	DET
ajbspi-122364	11	17	brain	brain	NOUN
ajbspi-122364	11	18	parenchyma	parenchyma	NOUN
ajbspi-122364	11	19	,	,	PUNCT
ajbspi-122364	11	20	but	but	CCONJ
ajbspi-122364	11	21	also	also	ADV
ajbspi-122364	11	22	participates	participate	VERB
ajbspi-122364	11	23	in	in	ADP
ajbspi-122364	11	24	maintaining	maintain	VERB
ajbspi-122364	11	25	ionic	ionic	ADJ
ajbspi-122364	11	26	balance	balance	NOUN
ajbspi-122364	11	27	,	,	PUNCT
ajbspi-122364	11	28	nutrient	nutrient	NOUN
ajbspi-122364	11	29	delivery	delivery	NOUN
ajbspi-122364	11	30	,	,	PUNCT
ajbspi-122364	11	31	and	and	CCONJ
ajbspi-122364	11	32	regulating	regulate	VERB
ajbspi-122364	11	33	neuroinflammatory	neuroinflammatory	ADJ
ajbspi-122364	11	34	reactions	reaction	NOUN
ajbspi-122364	11	35	.	.	PUNCT
ajbspi-122364	12	1	violation	violation	NOUN
ajbspi-122364	12	2	of	of	ADP
ajbspi-122364	12	3	the	the	DET
ajbspi-122364	12	4	integrity	integrity	NOUN
ajbspi-122364	12	5	and	and	CCONJ
ajbspi-122364	12	6	function	function	NOUN
ajbspi-122364	12	7	of	of	ADP
ajbspi-122364	12	8	the	the	DET
ajbspi-122364	12	9	bbb	bbb	PROPN
ajbspi-122364	12	10	underlies	underlie	VERB
ajbspi-122364	12	11	the	the	DET
ajbspi-122364	12	12	pathogenesis	pathogenesis	NOUN
ajbspi-122364	12	13	of	of	ADP
ajbspi-122364	12	14	a	a	DET
ajbspi-122364	12	15	wide	wide	ADJ
ajbspi-122364	12	16	range	range	NOUN
ajbspi-122364	12	17	of	of	ADP
ajbspi-122364	12	18	neurological	neurological	ADJ
ajbspi-122364	12	19	diseases	disease	NOUN
ajbspi-122364	12	20	,	,	PUNCT
ajbspi-122364	12	21	including	include	VERB
ajbspi-122364	12	22	ischemic	ischemic	ADJ
ajbspi-122364	12	23	and	and	CCONJ
ajbspi-122364	12	24	hemorrhagic	hemorrhagic	NOUN
ajbspi-122364	12	25	stroke	stroke	NOUN
ajbspi-122364	12	26	,	,	PUNCT
ajbspi-122364	12	27	neuroinfections	neuroinfection	NOUN
ajbspi-122364	12	28	,	,	PUNCT
ajbspi-122364	12	29	multiple	multiple	ADJ
ajbspi-122364	12	30	sclerosis	sclerosis	NOUN
ajbspi-122364	12	31	,	,	PUNCT
ajbspi-122364	12	32	alzheimer	alzheimer	PROPN
ajbspi-122364	12	33	's	's	PART
ajbspi-122364	12	34	disease	disease	NOUN
ajbspi-122364	12	35	and	and	CCONJ
ajbspi-122364	12	36	brain	brain	NOUN
ajbspi-122364	12	37	tumors	tumor	NOUN
ajbspi-122364	12	38	.	.	PUNCT
ajbspi-122364	13	1	modern	modern	ADJ
ajbspi-122364	13	2	concepts	concept	NOUN
ajbspi-122364	13	3	of	of	ADP
ajbspi-122364	13	4	the	the	DET
ajbspi-122364	13	5	structure	structure	NOUN
ajbspi-122364	13	6	and	and	CCONJ
ajbspi-122364	13	7	functions	function	NOUN
ajbspi-122364	13	8	of	of	ADP
ajbspi-122364	13	9	the	the	DET
ajbspi-122364	13	10	bbb	bbb	NOUN
ajbspi-122364	13	11	,	,	PUNCT
ajbspi-122364	13	12	as	as	ADV
ajbspi-122364	13	13	well	well	ADV
ajbspi-122364	13	14	as	as	ADP
ajbspi-122364	13	15	the	the	DET
ajbspi-122364	13	16	mechanisms	mechanism	NOUN
ajbspi-122364	13	17	of	of	ADP
ajbspi-122364	13	18	its	its	PRON
ajbspi-122364	13	19	disruption	disruption	NOUN
ajbspi-122364	13	20	,	,	PUNCT
ajbspi-122364	13	21	are	be	AUX
ajbspi-122364	13	22	important	important	ADJ
ajbspi-122364	13	23	not	not	PART
ajbspi-122364	13	24	only	only	ADV
ajbspi-122364	13	25	for	for	ADP
ajbspi-122364	13	26	diagnostics	diagnostic	NOUN
ajbspi-122364	13	27	,	,	PUNCT
ajbspi-122364	13	28	but	but	CCONJ
ajbspi-122364	13	29	also	also	ADV
ajbspi-122364	13	30	for	for	ADP
ajbspi-122364	13	31	the	the	DET
ajbspi-122364	13	32	development	development	NOUN
ajbspi-122364	13	33	of	of	ADP
ajbspi-122364	13	34	new	new	ADJ
ajbspi-122364	13	35	therapeutic	therapeutic	ADJ
ajbspi-122364	13	36	approaches	approach	NOUN
ajbspi-122364	13	37	,	,	PUNCT
ajbspi-122364	13	38	including	include	VERB
ajbspi-122364	13	39	methods	method	NOUN
ajbspi-122364	13	40	of	of	ADP
ajbspi-122364	13	41	targeted	target	VERB
ajbspi-122364	13	42	drug	drug	NOUN
ajbspi-122364	13	43	delivery	delivery	NOUN
ajbspi-122364	13	44	to	to	ADP
ajbspi-122364	13	45	the	the	DET
ajbspi-122364	13	46	central	central	ADJ
ajbspi-122364	13	47	nervous	nervous	ADJ
ajbspi-122364	13	48	system	system	NOUN
ajbspi-122364	13	49	.	.	PUNCT
ajbspi-122364	14	1	the	the	DET
ajbspi-122364	14	2	purpose	purpose	NOUN
ajbspi-122364	14	3	of	of	ADP
ajbspi-122364	14	4	this	this	DET
ajbspi-122364	14	5	article	article	NOUN
ajbspi-122364	14	6	is	be	AUX
ajbspi-122364	14	7	to	to	PART
ajbspi-122364	14	8	systematize	systematize	VERB
ajbspi-122364	14	9	existing	exist	VERB
ajbspi-122364	14	10	data	datum	NOUN
ajbspi-122364	14	11	on	on	ADP
ajbspi-122364	14	12	the	the	DET
ajbspi-122364	14	13	morphology	morphology	NOUN
ajbspi-122364	14	14	and	and	CCONJ
ajbspi-122364	14	15	functions	function	NOUN
ajbspi-122364	14	16	of	of	ADP
ajbspi-122364	14	17	the	the	DET
ajbspi-122364	14	18	bbb	bbb	NOUN
ajbspi-122364	14	19	,	,	PUNCT
ajbspi-122364	14	20	analyze	analyze	VERB
ajbspi-122364	14	21	the	the	DET
ajbspi-122364	14	22	neurological	neurological	ADJ
ajbspi-122364	14	23	consequences	consequence	NOUN
ajbspi-122364	14	24	of	of	ADP
ajbspi-122364	14	25	its	its	PRON
ajbspi-122364	14	26	disruption	disruption	NOUN
ajbspi-122364	14	27	,	,	PUNCT
ajbspi-122364	14	28	and	and	CCONJ
ajbspi-122364	14	29	consider	consider	VERB
ajbspi-122364	14	30	promising	promising	ADJ
ajbspi-122364	14	31	areas	area	NOUN
ajbspi-122364	14	32	in	in	ADP
ajbspi-122364	14	33	the	the	DET
ajbspi-122364	14	34	restoration	restoration	NOUN
ajbspi-122364	14	35	and	and	CCONJ
ajbspi-122364	14	36	modulation	modulation	NOUN
ajbspi-122364	14	37	of	of	ADP
ajbspi-122364	14	38	the	the	DET
ajbspi-122364	14	39	barrier	barrier	NOUN
ajbspi-122364	14	40	function	function	NOUN
ajbspi-122364	14	41	in	in	ADP
ajbspi-122364	14	42	various	various	ADJ
ajbspi-122364	14	43	diseases	disease	NOUN
ajbspi-122364	14	44	.	.	PUNCT
ajbspi-122364	15	1	purpose	purpose	NOUN
ajbspi-122364	15	2	of	of	ADP
ajbspi-122364	15	3	the	the	DET
ajbspi-122364	15	4	study	study	NOUN
ajbspi-122364	15	5	to	to	PART
ajbspi-122364	15	6	study	study	VERB
ajbspi-122364	15	7	the	the	DET
ajbspi-122364	15	8	structure	structure	NOUN
ajbspi-122364	15	9	and	and	CCONJ
ajbspi-122364	15	10	functions	function	NOUN
ajbspi-122364	15	11	of	of	ADP
ajbspi-122364	15	12	the	the	DET
ajbspi-122364	15	13	blood	blood	NOUN
ajbspi-122364	15	14	-	-	PUNCT
ajbspi-122364	15	15	brain	brain	NOUN
ajbspi-122364	15	16	barrier	barrier	NOUN
ajbspi-122364	15	17	and	and	CCONJ
ajbspi-122364	15	18	analyze	analyze	VERB
ajbspi-122364	15	19	the	the	DET
ajbspi-122364	15	20	consequences	consequence	NOUN
ajbspi-122364	15	21	of	of	ADP
ajbspi-122364	15	22	its	its	PRON
ajbspi-122364	15	23	disruption	disruption	NOUN
ajbspi-122364	15	24	in	in	ADP
ajbspi-122364	15	25	various	various	ADJ
ajbspi-122364	15	26	neurological	neurological	ADJ
ajbspi-122364	15	27	diseases	disease	NOUN
ajbspi-122364	15	28	.	.	PUNCT
ajbspi-122364	16	1	materials	material	NOUN
ajbspi-122364	16	2	and	and	CCONJ
ajbspi-122364	16	3	methods	method	NOUN
ajbspi-122364	16	4	the	the	DET
ajbspi-122364	16	5	study	study	NOUN
ajbspi-122364	16	6	used	use	VERB
ajbspi-122364	16	7	modern	modern	ADJ
ajbspi-122364	16	8	literature	literature	PROPN
ajbspi-122364	16	9	data	datum	NOUN
ajbspi-122364	16	10	,	,	PUNCT
ajbspi-122364	16	11	including	include	VERB
ajbspi-122364	16	12	experimental	experimental	ADJ
ajbspi-122364	16	13	and	and	CCONJ
ajbspi-122364	16	14	clinical	clinical	ADJ
ajbspi-122364	16	15	studies	study	NOUN
ajbspi-122364	16	16	devoted	devote	VERB
ajbspi-122364	16	17	to	to	ADP
ajbspi-122364	16	18	the	the	DET
ajbspi-122364	16	19	https://doi.org/10.37547/ajbspi/volume05issue06-06	https://doi.org/10.37547/ajbspi/volume05issue06-06	PROPN
ajbspi-122364	16	20	https://doi.org/10.37547/ajbspi/volume05issue06-06	https://doi.org/10.37547/ajbspi/volume05issue06-06	PROPN
ajbspi-122364	16	21	american	american	PROPN
ajbspi-122364	16	22	journal	journal	PROPN
ajbspi-122364	16	23	of	of	ADP
ajbspi-122364	16	24	applied	apply	VERB
ajbspi-122364	16	25	science	science	NOUN
ajbspi-122364	16	26	and	and	CCONJ
ajbspi-122364	16	27	technology	technology	NOUN
ajbspi-122364	16	28	26	26	NUM
ajbspi-122364	16	29	https://theusajournals.com/index.php/ajast	https://theusajournals.com/index.php/ajast	ADJ
ajbspi-122364	16	30	american	american	PROPN
ajbspi-122364	16	31	journal	journal	PROPN
ajbspi-122364	16	32	of	of	ADP
ajbspi-122364	16	33	applied	apply	VERB
ajbspi-122364	16	34	science	science	NOUN
ajbspi-122364	16	35	and	and	CCONJ
ajbspi-122364	16	36	technology	technology	NOUN
ajbspi-122364	16	37	(	(	PUNCT
ajbspi-122364	16	38	issn	issn	PROPN
ajbspi-122364	16	39	:	:	PUNCT
ajbspi-122364	16	40	2771	2771	NUM
ajbspi-122364	16	41	-	-	SYM
ajbspi-122364	16	42	2745	2745	NUM
ajbspi-122364	16	43	)	)	PUNCT
ajbspi-122364	16	44	morphology	morphology	NOUN
ajbspi-122364	16	45	,	,	PUNCT
ajbspi-122364	16	46	functions	function	NOUN
ajbspi-122364	16	47	and	and	CCONJ
ajbspi-122364	16	48	disorders	disorder	NOUN
ajbspi-122364	16	49	of	of	ADP
ajbspi-122364	16	50	the	the	DET
ajbspi-122364	16	51	blood	blood	NOUN
ajbspi-122364	16	52	-	-	PUNCT
ajbspi-122364	16	53	brain	brain	NOUN
ajbspi-122364	16	54	barrier	barrier	NOUN
ajbspi-122364	16	55	(	(	PUNCT
ajbspi-122364	16	56	bbb	bbb	PROPN
ajbspi-122364	16	57	)	)	PUNCT
ajbspi-122364	16	58	.	.	PUNCT
ajbspi-122364	17	1	the	the	DET
ajbspi-122364	17	2	analysis	analysis	NOUN
ajbspi-122364	17	3	was	be	AUX
ajbspi-122364	17	4	carried	carry	VERB
ajbspi-122364	17	5	out	out	ADP
ajbspi-122364	17	6	on	on	ADP
ajbspi-122364	17	7	the	the	DET
ajbspi-122364	17	8	basis	basis	NOUN
ajbspi-122364	17	9	of	of	ADP
ajbspi-122364	17	10	publications	publication	NOUN
ajbspi-122364	17	11	obtained	obtain	VERB
ajbspi-122364	17	12	from	from	ADP
ajbspi-122364	17	13	the	the	DET
ajbspi-122364	17	14	scientific	scientific	ADJ
ajbspi-122364	17	15	databases	database	NOUN
ajbspi-122364	17	16	pubmed	pubmed	PROPN
ajbspi-122364	17	17	,	,	PUNCT
ajbspi-122364	17	18	scopus	scopus	PROPN
ajbspi-122364	17	19	,	,	PUNCT
ajbspi-122364	17	20	web	web	NOUN
ajbspi-122364	17	21	of	of	ADP
ajbspi-122364	17	22	science	science	NOUN
ajbspi-122364	17	23	over	over	ADP
ajbspi-122364	17	24	the	the	DET
ajbspi-122364	17	25	past	past	ADJ
ajbspi-122364	17	26	10	10	NUM
ajbspi-122364	17	27	years	year	NOUN
ajbspi-122364	17	28	.	.	PUNCT
ajbspi-122364	18	1	to	to	PART
ajbspi-122364	18	2	illustrate	illustrate	VERB
ajbspi-122364	18	3	the	the	DET
ajbspi-122364	18	4	mechanisms	mechanism	NOUN
ajbspi-122364	18	5	of	of	ADP
ajbspi-122364	18	6	bbb	bbb	PROPN
ajbspi-122364	18	7	disruption	disruption	NOUN
ajbspi-122364	18	8	,	,	PUNCT
ajbspi-122364	18	9	the	the	DET
ajbspi-122364	18	10	results	result	NOUN
ajbspi-122364	18	11	of	of	ADP
ajbspi-122364	18	12	morphological	morphological	ADJ
ajbspi-122364	18	13	and	and	CCONJ
ajbspi-122364	18	14	biochemical	biochemical	ADJ
ajbspi-122364	18	15	studies	study	NOUN
ajbspi-122364	18	16	on	on	ADP
ajbspi-122364	18	17	animal	animal	NOUN
ajbspi-122364	18	18	models	model	NOUN
ajbspi-122364	18	19	of	of	ADP
ajbspi-122364	18	20	stroke	stroke	NOUN
ajbspi-122364	18	21	,	,	PUNCT
ajbspi-122364	18	22	neuroinfections	neuroinfection	NOUN
ajbspi-122364	18	23	and	and	CCONJ
ajbspi-122364	18	24	neurodegenerative	neurodegenerative	ADJ
ajbspi-122364	18	25	diseases	disease	NOUN
ajbspi-122364	18	26	,	,	PUNCT
ajbspi-122364	18	27	as	as	ADV
ajbspi-122364	18	28	well	well	ADV
ajbspi-122364	18	29	as	as	ADP
ajbspi-122364	18	30	data	datum	NOUN
ajbspi-122364	18	31	from	from	ADP
ajbspi-122364	18	32	clinical	clinical	ADJ
ajbspi-122364	18	33	observations	observation	NOUN
ajbspi-122364	18	34	of	of	ADP
ajbspi-122364	18	35	patients	patient	NOUN
ajbspi-122364	18	36	with	with	ADP
ajbspi-122364	18	37	similar	similar	ADJ
ajbspi-122364	18	38	pathologies	pathology	NOUN
ajbspi-122364	18	39	are	be	AUX
ajbspi-122364	18	40	considered	consider	VERB
ajbspi-122364	18	41	.	.	PUNCT
ajbspi-122364	19	1	methods	method	NOUN
ajbspi-122364	19	2	included	include	VERB
ajbspi-122364	19	3	studying	study	VERB
ajbspi-122364	19	4	the	the	DET
ajbspi-122364	19	5	barrier	barrier	NOUN
ajbspi-122364	19	6	structure	structure	NOUN
ajbspi-122364	19	7	using	use	VERB
ajbspi-122364	19	8	electron	electron	NOUN
ajbspi-122364	19	9	microscopy	microscopy	NOUN
ajbspi-122364	19	10	,	,	PUNCT
ajbspi-122364	19	11	immunohistochemical	immunohistochemical	ADJ
ajbspi-122364	19	12	analysis	analysis	NOUN
ajbspi-122364	19	13	of	of	ADP
ajbspi-122364	19	14	tight	tight	ADJ
ajbspi-122364	19	15	junctions	junction	NOUN
ajbspi-122364	19	16	(	(	PUNCT
ajbspi-122364	19	17	tight	tight	ADJ
ajbspi-122364	19	18	junction	junction	NOUN
ajbspi-122364	19	19	proteins	protein	NOUN
ajbspi-122364	19	20	)	)	PUNCT
ajbspi-122364	19	21	,	,	PUNCT
ajbspi-122364	19	22	as	as	ADV
ajbspi-122364	19	23	well	well	ADV
ajbspi-122364	19	24	as	as	ADP
ajbspi-122364	19	25	assessment	assessment	NOUN
ajbspi-122364	19	26	of	of	ADP
ajbspi-122364	19	27	functional	functional	ADJ
ajbspi-122364	19	28	permeability	permeability	NOUN
ajbspi-122364	19	29	using	use	VERB
ajbspi-122364	19	30	contrast	contrast	NOUN
ajbspi-122364	19	31	imaging	imaging	NOUN
ajbspi-122364	19	32	techniques	technique	NOUN
ajbspi-122364	19	33	and	and	CCONJ
ajbspi-122364	19	34	inflammatory	inflammatory	ADJ
ajbspi-122364	19	35	biomarkers	biomarker	NOUN
ajbspi-122364	19	36	.	.	PUNCT
ajbspi-122364	20	1	results	result	NOUN
ajbspi-122364	20	2	and	and	CCONJ
ajbspi-122364	20	3	discussion	discussion	VERB
ajbspi-122364	20	4	the	the	DET
ajbspi-122364	20	5	analysis	analysis	NOUN
ajbspi-122364	20	6	of	of	ADP
ajbspi-122364	20	7	literature	literature	NOUN
ajbspi-122364	20	8	and	and	CCONJ
ajbspi-122364	20	9	experimental	experimental	ADJ
ajbspi-122364	20	10	data	datum	NOUN
ajbspi-122364	20	11	confirmed	confirm	VERB
ajbspi-122364	20	12	the	the	DET
ajbspi-122364	20	13	complex	complex	ADJ
ajbspi-122364	20	14	and	and	CCONJ
ajbspi-122364	20	15	multi	multi	ADJ
ajbspi-122364	20	16	-	-	ADJ
ajbspi-122364	20	17	level	level	ADJ
ajbspi-122364	20	18	structure	structure	NOUN
ajbspi-122364	20	19	of	of	ADP
ajbspi-122364	20	20	the	the	DET
ajbspi-122364	20	21	blood	blood	NOUN
ajbspi-122364	20	22	-	-	PUNCT
ajbspi-122364	20	23	brain	brain	NOUN
ajbspi-122364	20	24	barrier	barrier	NOUN
ajbspi-122364	20	25	(	(	PUNCT
ajbspi-122364	20	26	bbb	bbb	PROPN
ajbspi-122364	20	27	)	)	PUNCT
ajbspi-122364	20	28	,	,	PUNCT
ajbspi-122364	20	29	which	which	PRON
ajbspi-122364	20	30	ensures	ensure	VERB
ajbspi-122364	20	31	its	its	PRON
ajbspi-122364	20	32	high	high	ADJ
ajbspi-122364	20	33	selectivity	selectivity	NOUN
ajbspi-122364	20	34	and	and	CCONJ
ajbspi-122364	20	35	protective	protective	ADJ
ajbspi-122364	20	36	function	function	NOUN
ajbspi-122364	20	37	.	.	PUNCT
ajbspi-122364	21	1	endothelial	endothelial	ADJ
ajbspi-122364	21	2	cells	cell	NOUN
ajbspi-122364	21	3	with	with	ADP
ajbspi-122364	21	4	tight	tight	ADJ
ajbspi-122364	21	5	junctions	junction	NOUN
ajbspi-122364	21	6	(	(	PUNCT
ajbspi-122364	21	7	claudin	claudin	VERB
ajbspi-122364	21	8	,	,	PUNCT
ajbspi-122364	21	9	occludin	occludin	NOUN
ajbspi-122364	21	10	,	,	PUNCT
ajbspi-122364	21	11	zo-1	zo-1	NUM
ajbspi-122364	21	12	)	)	PUNCT
ajbspi-122364	21	13	form	form	VERB
ajbspi-122364	21	14	the	the	DET
ajbspi-122364	21	15	main	main	ADJ
ajbspi-122364	21	16	physical	physical	ADJ
ajbspi-122364	21	17	barrier	barrier	NOUN
ajbspi-122364	21	18	,	,	PUNCT
ajbspi-122364	21	19	supported	support	VERB
ajbspi-122364	21	20	by	by	ADP
ajbspi-122364	21	21	astrocytic	astrocytic	ADJ
ajbspi-122364	21	22	endothelial	endothelial	ADJ
ajbspi-122364	21	23	cells	cell	NOUN
ajbspi-122364	21	24	and	and	CCONJ
ajbspi-122364	21	25	pericytes	pericyte	NOUN
ajbspi-122364	21	26	.	.	PUNCT
ajbspi-122364	22	1	violation	violation	NOUN
ajbspi-122364	22	2	of	of	ADP
ajbspi-122364	22	3	the	the	DET
ajbspi-122364	22	4	integrity	integrity	NOUN
ajbspi-122364	22	5	of	of	ADP
ajbspi-122364	22	6	these	these	DET
ajbspi-122364	22	7	components	component	NOUN
ajbspi-122364	22	8	leads	lead	VERB
ajbspi-122364	22	9	to	to	ADP
ajbspi-122364	22	10	increased	increase	VERB
ajbspi-122364	22	11	permeability	permeability	NOUN
ajbspi-122364	22	12	of	of	ADP
ajbspi-122364	22	13	the	the	DET
ajbspi-122364	22	14	bbb	bbb	NOUN
ajbspi-122364	22	15	and	and	CCONJ
ajbspi-122364	22	16	the	the	DET
ajbspi-122364	22	17	development	development	NOUN
ajbspi-122364	22	18	of	of	ADP
ajbspi-122364	22	19	neurological	neurological	ADJ
ajbspi-122364	22	20	complications	complication	NOUN
ajbspi-122364	22	21	.	.	PUNCT
ajbspi-122364	23	1	strokes	stroke	NOUN
ajbspi-122364	23	2	are	be	AUX
ajbspi-122364	23	3	associated	associate	VERB
ajbspi-122364	23	4	with	with	ADP
ajbspi-122364	23	5	significant	significant	ADJ
ajbspi-122364	23	6	weakening	weakening	NOUN
ajbspi-122364	23	7	of	of	ADP
ajbspi-122364	23	8	tight	tight	ADJ
ajbspi-122364	23	9	junctions	junction	NOUN
ajbspi-122364	23	10	and	and	CCONJ
ajbspi-122364	23	11	activation	activation	NOUN
ajbspi-122364	23	12	of	of	ADP
ajbspi-122364	23	13	matrix	matrix	NOUN
ajbspi-122364	23	14	metalloproteinases	metalloproteinase	NOUN
ajbspi-122364	23	15	(	(	PUNCT
ajbspi-122364	23	16	mmp-9	mmp-9	NUM
ajbspi-122364	23	17	)	)	PUNCT
ajbspi-122364	23	18	,	,	PUNCT
ajbspi-122364	23	19	which	which	PRON
ajbspi-122364	23	20	is	be	AUX
ajbspi-122364	23	21	accompanied	accompany	VERB
ajbspi-122364	23	22	by	by	ADP
ajbspi-122364	23	23	vasogenic	vasogenic	ADJ
ajbspi-122364	23	24	edema	edema	NOUN
ajbspi-122364	23	25	and	and	CCONJ
ajbspi-122364	23	26	increased	increase	VERB
ajbspi-122364	23	27	inflammation	inflammation	NOUN
ajbspi-122364	23	28	.	.	PUNCT
ajbspi-122364	24	1	these	these	DET
ajbspi-122364	24	2	processes	process	NOUN
ajbspi-122364	24	3	contribute	contribute	VERB
ajbspi-122364	24	4	to	to	ADP
ajbspi-122364	24	5	secondary	secondary	ADJ
ajbspi-122364	24	6	damage	damage	NOUN
ajbspi-122364	24	7	to	to	ADP
ajbspi-122364	24	8	brain	brain	NOUN
ajbspi-122364	24	9	tissue	tissue	NOUN
ajbspi-122364	24	10	and	and	CCONJ
ajbspi-122364	24	11	worsen	worsen	VERB
ajbspi-122364	24	12	the	the	DET
ajbspi-122364	24	13	prognosis	prognosis	NOUN
ajbspi-122364	24	14	.	.	PUNCT
ajbspi-122364	25	1	similarly	similarly	ADV
ajbspi-122364	25	2	,	,	PUNCT
ajbspi-122364	25	3	in	in	ADP
ajbspi-122364	25	4	neuroinfections	neuroinfection	NOUN
ajbspi-122364	25	5	,	,	PUNCT
ajbspi-122364	25	6	pathogens	pathogen	NOUN
ajbspi-122364	25	7	and	and	CCONJ
ajbspi-122364	25	8	inflammatory	inflammatory	ADJ
ajbspi-122364	25	9	mediators	mediator	NOUN
ajbspi-122364	25	10	destroy	destroy	VERB
ajbspi-122364	25	11	the	the	DET
ajbspi-122364	25	12	barrier	barrier	NOUN
ajbspi-122364	25	13	,	,	PUNCT
ajbspi-122364	25	14	facilitating	facilitate	VERB
ajbspi-122364	25	15	access	access	NOUN
ajbspi-122364	25	16	for	for	ADP
ajbspi-122364	25	17	immune	immune	ADJ
ajbspi-122364	25	18	cells	cell	NOUN
ajbspi-122364	25	19	,	,	PUNCT
ajbspi-122364	25	20	but	but	CCONJ
ajbspi-122364	25	21	simultaneously	simultaneously	ADV
ajbspi-122364	25	22	increasing	increase	VERB
ajbspi-122364	25	23	the	the	DET
ajbspi-122364	25	24	risk	risk	NOUN
ajbspi-122364	25	25	of	of	ADP
ajbspi-122364	25	26	edema	edema	NOUN
ajbspi-122364	25	27	and	and	CCONJ
ajbspi-122364	25	28	neuronal	neuronal	ADJ
ajbspi-122364	25	29	damage	damage	NOUN
ajbspi-122364	25	30	.	.	PUNCT
ajbspi-122364	26	1	in	in	ADP
ajbspi-122364	26	2	neurodegenerative	neurodegenerative	ADJ
ajbspi-122364	26	3	diseases	disease	NOUN
ajbspi-122364	26	4	such	such	ADJ
ajbspi-122364	26	5	as	as	ADP
ajbspi-122364	26	6	alzheimer	alzheimer	NOUN
ajbspi-122364	26	7	's	's	PART
ajbspi-122364	26	8	disease	disease	NOUN
ajbspi-122364	26	9	and	and	CCONJ
ajbspi-122364	26	10	multiple	multiple	ADJ
ajbspi-122364	26	11	sclerosis	sclerosis	NOUN
ajbspi-122364	26	12	,	,	PUNCT
ajbspi-122364	26	13	bbb	bbb	PROPN
ajbspi-122364	26	14	dysfunction	dysfunction	NOUN
ajbspi-122364	26	15	is	be	AUX
ajbspi-122364	26	16	associated	associate	VERB
ajbspi-122364	26	17	with	with	ADP
ajbspi-122364	26	18	impaired	impaired	ADJ
ajbspi-122364	26	19	β	β	NOUN
ajbspi-122364	26	20	-	-	ADJ
ajbspi-122364	26	21	amyloid	amyloid	ADJ
ajbspi-122364	26	22	transport	transport	NOUN
ajbspi-122364	26	23	,	,	PUNCT
ajbspi-122364	26	24	increased	increase	VERB
ajbspi-122364	26	25	neuroinflammation	neuroinflammation	NOUN
ajbspi-122364	26	26	,	,	PUNCT
ajbspi-122364	26	27	and	and	CCONJ
ajbspi-122364	26	28	lymphocyte	lymphocyte	ADJ
ajbspi-122364	26	29	infiltration	infiltration	NOUN
ajbspi-122364	26	30	into	into	ADP
ajbspi-122364	26	31	the	the	DET
ajbspi-122364	26	32	cns	cns	NOUN
ajbspi-122364	26	33	,	,	PUNCT
ajbspi-122364	26	34	which	which	PRON
ajbspi-122364	26	35	accelerates	accelerate	VERB
ajbspi-122364	26	36	disease	disease	NOUN
ajbspi-122364	26	37	progression	progression	NOUN
ajbspi-122364	26	38	.	.	PUNCT
ajbspi-122364	27	1	tumor	tumor	NOUN
ajbspi-122364	27	2	growth	growth	NOUN
ajbspi-122364	27	3	,	,	PUNCT
ajbspi-122364	27	4	especially	especially	ADV
ajbspi-122364	27	5	in	in	ADP
ajbspi-122364	27	6	glioblastomas	glioblastoma	NOUN
ajbspi-122364	27	7	,	,	PUNCT
ajbspi-122364	27	8	is	be	AUX
ajbspi-122364	27	9	accompanied	accompany	VERB
ajbspi-122364	27	10	by	by	ADP
ajbspi-122364	27	11	the	the	DET
ajbspi-122364	27	12	secretion	secretion	NOUN
ajbspi-122364	27	13	of	of	ADP
ajbspi-122364	27	14	factors	factor	NOUN
ajbspi-122364	27	15	that	that	PRON
ajbspi-122364	27	16	destroy	destroy	VERB
ajbspi-122364	27	17	the	the	DET
ajbspi-122364	27	18	barrier	barrier	NOUN
ajbspi-122364	27	19	and	and	CCONJ
ajbspi-122364	27	20	cause	cause	VERB
ajbspi-122364	27	21	vasogenic	vasogenic	ADJ
ajbspi-122364	27	22	edema	edema	NOUN
ajbspi-122364	27	23	,	,	PUNCT
ajbspi-122364	27	24	which	which	PRON
ajbspi-122364	27	25	complicates	complicate	VERB
ajbspi-122364	27	26	treatment	treatment	NOUN
ajbspi-122364	27	27	and	and	CCONJ
ajbspi-122364	27	28	worsens	worsen	VERB
ajbspi-122364	27	29	the	the	DET
ajbspi-122364	27	30	quality	quality	NOUN
ajbspi-122364	27	31	of	of	ADP
ajbspi-122364	27	32	life	life	NOUN
ajbspi-122364	27	33	of	of	ADP
ajbspi-122364	27	34	patients	patient	NOUN
ajbspi-122364	27	35	.	.	PUNCT
ajbspi-122364	28	1	modern	modern	ADJ
ajbspi-122364	28	2	diagnostic	diagnostic	ADJ
ajbspi-122364	28	3	methods	method	NOUN
ajbspi-122364	28	4	,	,	PUNCT
ajbspi-122364	28	5	including	include	VERB
ajbspi-122364	28	6	contrast	contrast	NOUN
ajbspi-122364	28	7	mri	mri	NOUN
ajbspi-122364	28	8	and	and	CCONJ
ajbspi-122364	28	9	inflammation	inflammation	NOUN
ajbspi-122364	28	10	biomarkers	biomarker	NOUN
ajbspi-122364	28	11	,	,	PUNCT
ajbspi-122364	28	12	allow	allow	VERB
ajbspi-122364	28	13	for	for	ADP
ajbspi-122364	28	14	timely	timely	ADJ
ajbspi-122364	28	15	detection	detection	NOUN
ajbspi-122364	28	16	of	of	ADP
ajbspi-122364	28	17	bbb	bbb	PROPN
ajbspi-122364	28	18	disruptions	disruption	NOUN
ajbspi-122364	28	19	.	.	PUNCT
ajbspi-122364	29	1	therapeutic	therapeutic	ADJ
ajbspi-122364	29	2	strategies	strategy	NOUN
ajbspi-122364	29	3	aimed	aim	VERB
ajbspi-122364	29	4	at	at	ADP
ajbspi-122364	29	5	barrier	barrier	NOUN
ajbspi-122364	29	6	stabilization	stabilization	NOUN
ajbspi-122364	29	7	,	,	PUNCT
ajbspi-122364	29	8	mmp	mmp	PROPN
ajbspi-122364	29	9	inhibition	inhibition	NOUN
ajbspi-122364	29	10	,	,	PUNCT
ajbspi-122364	29	11	and	and	CCONJ
ajbspi-122364	29	12	targeted	target	VERB
ajbspi-122364	29	13	drug	drug	NOUN
ajbspi-122364	29	14	delivery	delivery	NOUN
ajbspi-122364	29	15	through	through	ADP
ajbspi-122364	29	16	temporary	temporary	ADJ
ajbspi-122364	29	17	bbb	bbb	NOUN
ajbspi-122364	29	18	opening	opening	NOUN
ajbspi-122364	29	19	show	show	NOUN
ajbspi-122364	29	20	promise	promise	NOUN
ajbspi-122364	29	21	for	for	ADP
ajbspi-122364	29	22	improving	improve	VERB
ajbspi-122364	29	23	clinical	clinical	ADJ
ajbspi-122364	29	24	outcomes	outcome	NOUN
ajbspi-122364	29	25	.	.	PUNCT
ajbspi-122364	30	1	thus	thus	ADV
ajbspi-122364	30	2	,	,	PUNCT
ajbspi-122364	30	3	maintaining	maintain	VERB
ajbspi-122364	30	4	the	the	DET
ajbspi-122364	30	5	integrity	integrity	NOUN
ajbspi-122364	30	6	of	of	ADP
ajbspi-122364	30	7	the	the	DET
ajbspi-122364	30	8	bbb	bbb	PROPN
ajbspi-122364	30	9	is	be	AUX
ajbspi-122364	30	10	critical	critical	ADJ
ajbspi-122364	30	11	for	for	ADP
ajbspi-122364	30	12	neuroprotection	neuroprotection	NOUN
ajbspi-122364	30	13	and	and	CCONJ
ajbspi-122364	30	14	effective	effective	ADJ
ajbspi-122364	30	15	treatment	treatment	NOUN
ajbspi-122364	30	16	of	of	ADP
ajbspi-122364	30	17	many	many	ADJ
ajbspi-122364	30	18	cns	cns	NOUN
ajbspi-122364	30	19	diseases	disease	NOUN
ajbspi-122364	30	20	.	.	PUNCT
ajbspi-122364	31	1	conclusion	conclusion	VERB
ajbspi-122364	31	2	the	the	DET
ajbspi-122364	31	3	blood	blood	NOUN
ajbspi-122364	31	4	-	-	PUNCT
ajbspi-122364	31	5	brain	brain	NOUN
ajbspi-122364	31	6	barrier	barrier	NOUN
ajbspi-122364	31	7	is	be	AUX
ajbspi-122364	31	8	a	a	DET
ajbspi-122364	31	9	key	key	ADJ
ajbspi-122364	31	10	element	element	NOUN
ajbspi-122364	31	11	of	of	ADP
ajbspi-122364	31	12	brain	brain	NOUN
ajbspi-122364	31	13	protection	protection	NOUN
ajbspi-122364	31	14	,	,	PUNCT
ajbspi-122364	31	15	ensuring	ensure	VERB
ajbspi-122364	31	16	selective	selective	ADJ
ajbspi-122364	31	17	transport	transport	NOUN
ajbspi-122364	31	18	of	of	ADP
ajbspi-122364	31	19	substances	substance	NOUN
ajbspi-122364	31	20	and	and	CCONJ
ajbspi-122364	31	21	maintaining	maintain	VERB
ajbspi-122364	31	22	homeostasis	homeostasis	NOUN
ajbspi-122364	31	23	of	of	ADP
ajbspi-122364	31	24	the	the	DET
ajbspi-122364	31	25	central	central	ADJ
ajbspi-122364	31	26	nervous	nervous	ADJ
ajbspi-122364	31	27	system	system	NOUN
ajbspi-122364	31	28	.	.	PUNCT
ajbspi-122364	32	1	disruptions	disruption	NOUN
ajbspi-122364	32	2	in	in	ADP
ajbspi-122364	32	3	the	the	DET
ajbspi-122364	32	4	integrity	integrity	NOUN
ajbspi-122364	32	5	and	and	CCONJ
ajbspi-122364	32	6	function	function	NOUN
ajbspi-122364	32	7	of	of	ADP
ajbspi-122364	32	8	the	the	DET
ajbspi-122364	32	9	bbb	bbb	PROPN
ajbspi-122364	32	10	play	play	VERB
ajbspi-122364	32	11	an	an	DET
ajbspi-122364	32	12	important	important	ADJ
ajbspi-122364	32	13	role	role	NOUN
ajbspi-122364	32	14	in	in	ADP
ajbspi-122364	32	15	the	the	DET
ajbspi-122364	32	16	pathogenesis	pathogenesis	NOUN
ajbspi-122364	32	17	of	of	ADP
ajbspi-122364	32	18	many	many	ADJ
ajbspi-122364	32	19	neurological	neurological	ADJ
ajbspi-122364	32	20	diseases	disease	NOUN
ajbspi-122364	32	21	,	,	PUNCT
ajbspi-122364	32	22	including	include	VERB
ajbspi-122364	32	23	strokes	stroke	NOUN
ajbspi-122364	32	24	,	,	PUNCT
ajbspi-122364	32	25	neuroinfections	neuroinfection	NOUN
ajbspi-122364	32	26	,	,	PUNCT
ajbspi-122364	32	27	neurodegenerative	neurodegenerative	ADJ
ajbspi-122364	32	28	processes	process	NOUN
ajbspi-122364	32	29	and	and	CCONJ
ajbspi-122364	32	30	brain	brain	NOUN
ajbspi-122364	32	31	tumors	tumor	NOUN
ajbspi-122364	32	32	.	.	PUNCT
ajbspi-122364	33	1	understanding	understand	VERB
ajbspi-122364	33	2	the	the	DET
ajbspi-122364	33	3	mechanisms	mechanism	NOUN
ajbspi-122364	33	4	of	of	ADP
ajbspi-122364	33	5	barrier	barrier	NOUN
ajbspi-122364	33	6	disruption	disruption	NOUN
ajbspi-122364	33	7	opens	open	VERB
ajbspi-122364	33	8	up	up	ADP
ajbspi-122364	33	9	new	new	ADJ
ajbspi-122364	33	10	opportunities	opportunity	NOUN
ajbspi-122364	33	11	for	for	ADP
ajbspi-122364	33	12	diagnostics	diagnostic	NOUN
ajbspi-122364	33	13	and	and	CCONJ
ajbspi-122364	33	14	the	the	DET
ajbspi-122364	33	15	development	development	NOUN
ajbspi-122364	33	16	of	of	ADP
ajbspi-122364	33	17	effective	effective	ADJ
ajbspi-122364	33	18	therapeutic	therapeutic	ADJ
ajbspi-122364	33	19	approaches	approach	NOUN
ajbspi-122364	33	20	aimed	aim	VERB
ajbspi-122364	33	21	at	at	ADP
ajbspi-122364	33	22	restoring	restore	VERB
ajbspi-122364	33	23	and	and	CCONJ
ajbspi-122364	33	24	modulating	modulate	VERB
ajbspi-122364	33	25	its	its	PRON
ajbspi-122364	33	26	function	function	NOUN
ajbspi-122364	33	27	.	.	PUNCT
ajbspi-122364	34	1	further	further	ADJ
ajbspi-122364	34	2	research	research	NOUN
ajbspi-122364	34	3	in	in	ADP
ajbspi-122364	34	4	this	this	DET
ajbspi-122364	34	5	area	area	NOUN
ajbspi-122364	34	6	will	will	AUX
ajbspi-122364	34	7	contribute	contribute	VERB
ajbspi-122364	34	8	to	to	ADP
ajbspi-122364	34	9	improving	improve	VERB
ajbspi-122364	34	10	the	the	DET
ajbspi-122364	34	11	treatment	treatment	NOUN
ajbspi-122364	34	12	and	and	CCONJ
ajbspi-122364	34	13	prevention	prevention	NOUN
ajbspi-122364	34	14	of	of	ADP
ajbspi-122364	34	15	neurological	neurological	ADJ
ajbspi-122364	34	16	disorders	disorder	NOUN
ajbspi-122364	34	17	.	.	PUNCT
ajbspi-122364	35	1	references	reference	NOUN
ajbspi-122364	35	2	1	1	NUM
ajbspi-122364	35	3	.	.	PUNCT
ajbspi-122364	35	4	abbott	abbott	PROPN
ajbspi-122364	35	5	nj	nj	PROPN
ajbspi-122364	35	6	,	,	PUNCT
ajbspi-122364	35	7	patabendige	patabendige	NOUN
ajbspi-122364	35	8	aak	aak	NOUN
ajbspi-122364	35	9	,	,	PUNCT
ajbspi-122364	35	10	dolman	dolman	PROPN
ajbspi-122364	35	11	dem	dem	PROPN
ajbspi-122364	35	12	,	,	PUNCT
ajbspi-122364	35	13	yusof	yusof	PROPN
ajbspi-122364	35	14	sr	sr	PROPN
ajbspi-122364	35	15	,	,	PUNCT
ajbspi-122364	35	16	begley	begley	NOUN
ajbspi-122364	35	17	dj	dj	NOUN
ajbspi-122364	35	18	structure	structure	NOUN
ajbspi-122364	35	19	and	and	CCONJ
ajbspi-122364	35	20	function	function	NOUN
ajbspi-122364	35	21	of	of	ADP
ajbspi-122364	35	22	the	the	DET
ajbspi-122364	35	23	blood	blood	NOUN
ajbspi-122364	35	24	–	–	PUNCT
ajbspi-122364	35	25	brain	brain	NOUN
ajbspi-122364	35	26	barrier	barrier	NOUN
ajbspi-122364	35	27	.	.	PUNCT
ajbspi-122364	36	1	neurobiology	neurobiology	NOUN
ajbspi-122364	36	2	of	of	ADP
ajbspi-122364	36	3	disease	disease	NOUN
ajbspi-122364	36	4	.	.	PUNCT
ajbspi-122364	37	1	2010;37(1):13	2010;37(1):13	NUM
ajbspi-122364	37	2	-	-	SYM
ajbspi-122364	37	3	25	25	NUM
ajbspi-122364	37	4	.	.	NOUN
ajbspi-122364	37	5	2	2	X
ajbspi-122364	37	6	.	.	X
ajbspi-122364	37	7	zlokovic	zlokovic	PROPN
ajbspi-122364	37	8	bv	bv	PROPN
ajbspi-122364	38	1	the	the	DET
ajbspi-122364	38	2	blood	blood	NOUN
ajbspi-122364	38	3	-	-	PUNCT
ajbspi-122364	38	4	brain	brain	NOUN
ajbspi-122364	38	5	barrier	barrier	NOUN
ajbspi-122364	38	6	in	in	ADP
ajbspi-122364	38	7	health	health	NOUN
ajbspi-122364	38	8	and	and	CCONJ
ajbspi-122364	38	9	chronic	chronic	ADJ
ajbspi-122364	38	10	neurodegenerative	neurodegenerative	ADJ
ajbspi-122364	38	11	disorders	disorder	NOUN
ajbspi-122364	38	12	.	.	PUNCT
ajbspi-122364	39	1	neuron	neuron	PROPN
ajbspi-122364	39	2	.	.	PUNCT
ajbspi-122364	40	1	2008;57(2):178	2008;57(2):178	NUM
ajbspi-122364	40	2	-	-	PUNCT
ajbspi-122364	40	3	201	201	NUM
ajbspi-122364	40	4	.	.	PUNCT
ajbspi-122364	41	1	3	3	X
ajbspi-122364	41	2	.	.	X
ajbspi-122364	41	3	obermeier	obermeier	PROPN
ajbspi-122364	41	4	b.	b.	PROPN
ajbspi-122364	41	5	,	,	PUNCT
ajbspi-122364	41	6	daneman	daneman	PROPN
ajbspi-122364	41	7	r.	r.	PROPN
ajbspi-122364	41	8	,	,	PUNCT
ajbspi-122364	41	9	ransohoff	ransohoff	PROPN
ajbspi-122364	41	10	rm	rm	PROPN
ajbspi-122364	41	11	development	development	PROPN
ajbspi-122364	41	12	,	,	PUNCT
ajbspi-122364	41	13	maintenance	maintenance	NOUN
ajbspi-122364	41	14	and	and	CCONJ
ajbspi-122364	41	15	disruption	disruption	NOUN
ajbspi-122364	41	16	of	of	ADP
ajbspi-122364	41	17	the	the	DET
ajbspi-122364	41	18	blood	blood	NOUN
ajbspi-122364	41	19	-	-	PUNCT
ajbspi-122364	41	20	brain	brain	NOUN
ajbspi-122364	41	21	barrier	barrier	NOUN
ajbspi-122364	41	22	.	.	PUNCT
ajbspi-122364	42	1	nature	nature	NOUN
ajbspi-122364	42	2	medicine	medicine	NOUN
ajbspi-122364	42	3	.	.	PUNCT
ajbspi-122364	43	1	2013;19(12):1584	2013;19(12):1584	X
ajbspi-122364	43	2	-	-	NOUN
ajbspi-122364	43	3	1596	1596	NUM
ajbspi-122364	43	4	.	.	PUNCT
ajbspi-122364	44	1	4	4	X
ajbspi-122364	44	2	.	.	X
ajbspi-122364	44	3	daneman	daneman	PROPN
ajbspi-122364	44	4	r.	r.	PROPN
ajbspi-122364	44	5	,	,	PUNCT
ajbspi-122364	44	6	prat	prat	NOUN
ajbspi-122364	44	7	a.	a.	NOUN
ajbspi-122364	44	8	the	the	DET
ajbspi-122364	44	9	blood	blood	NOUN
ajbspi-122364	44	10	-	-	PUNCT
ajbspi-122364	44	11	brain	brain	NOUN
ajbspi-122364	44	12	barrier	barrier	NOUN
ajbspi-122364	44	13	.	.	PUNCT
ajbspi-122364	45	1	cold	cold	ADJ
ajbspi-122364	45	2	spring	spring	NOUN
ajbspi-122364	45	3	harbor	harbor	NOUN
ajbspi-122364	45	4	perspectives	perspective	NOUN
ajbspi-122364	45	5	in	in	ADP
ajbspi-122364	45	6	biology	biology	NOUN
ajbspi-122364	45	7	.	.	PUNCT
ajbspi-122364	46	1	2015;7(1	2015;7(1	NUM
ajbspi-122364	46	2	):	):	PUNCT
ajbspi-122364	46	3	a020412	a020412	NOUN
ajbspi-122364	46	4	.	.	NOUN
ajbspi-122364	47	1	5	5	NUM
ajbspi-122364	47	2	.	.	X
ajbspi-122364	47	3	sweeney	sweeney	PROPN
ajbspi-122364	47	4	md	md	PROPN
ajbspi-122364	47	5	,	,	PUNCT
ajbspi-122364	47	6	zhao	zhao	PROPN
ajbspi-122364	47	7	z.	z.	PROPN
ajbspi-122364	47	8	,	,	PUNCT
ajbspi-122364	47	9	montagne	montagne	PROPN
ajbspi-122364	47	10	a.	a.	PROPN
ajbspi-122364	47	11	,	,	PUNCT
ajbspi-122364	47	12	nelson	nelson	PROPN
ajbspi-122364	47	13	ar	ar	PROPN
ajbspi-122364	47	14	,	,	PUNCT
ajbspi-122364	47	15	zlokovic	zlokovic	PROPN
ajbspi-122364	47	16	bv	bv	PROPN
ajbspi-122364	47	17	blood	blood	NOUN
ajbspi-122364	47	18	–	–	PUNCT
ajbspi-122364	47	19	brain	brain	NOUN
ajbspi-122364	47	20	barrier	barrier	NOUN
ajbspi-122364	47	21	:	:	PUNCT
ajbspi-122364	47	22	from	from	ADP
ajbspi-122364	47	23	physiology	physiology	NOUN
ajbspi-122364	47	24	to	to	ADP
ajbspi-122364	47	25	disease	disease	NOUN
ajbspi-122364	47	26	and	and	CCONJ
ajbspi-122364	47	27	back	back	NOUN
ajbspi-122364	47	28	.	.	PUNCT
ajbspi-122364	48	1	physiological	physiological	ADJ
ajbspi-122364	48	2	reviews	review	NOUN
ajbspi-122364	48	3	.	.	PUNCT
ajbspi-122364	49	1	2019;99(1):21	2019;99(1):21	X
ajbspi-122364	49	2	-	-	SYM
ajbspi-122364	49	3	78	78	NUM
ajbspi-122364	49	4	.	.	PUNCT
ajbspi-122364	50	1	6	6	NUM
ajbspi-122364	50	2	.	.	PUNCT
ajbspi-122364	50	3	engelhardt	engelhardt	PROPN
ajbspi-122364	50	4	b.	b.	PROPN
ajbspi-122364	50	5	,	,	PUNCT
ajbspi-122364	50	6	liebner	liebner	PROPN
ajbspi-122364	50	7	s.	s.	PROPN
ajbspi-122364	50	8	novel	novel	PROPN
ajbspi-122364	50	9	insights	insight	NOUN
ajbspi-122364	50	10	into	into	ADP
ajbspi-122364	50	11	the	the	DET
ajbspi-122364	50	12	development	development	NOUN
ajbspi-122364	50	13	and	and	CCONJ
ajbspi-122364	50	14	maintenance	maintenance	NOUN
ajbspi-122364	50	15	of	of	ADP
ajbspi-122364	50	16	the	the	DET
ajbspi-122364	50	17	blood	blood	NOUN
ajbspi-122364	50	18	–	–	PUNCT
ajbspi-122364	50	19	brain	brain	NOUN
ajbspi-122364	50	20	barrier	barrier	NOUN
ajbspi-122364	50	21	.	.	PUNCT
ajbspi-122364	51	1	cell	cell	NOUN
ajbspi-122364	51	2	and	and	CCONJ
ajbspi-122364	51	3	tissue	tissue	NOUN
ajbspi-122364	51	4	research	research	NOUN
ajbspi-122364	51	5	.	.	PUNCT
ajbspi-122364	52	1	2014;355(3):687699	2014;355(3):687699	NUM
ajbspi-122364	52	2	.	.	X
ajbspi-122364	52	3	7	7	X
ajbspi-122364	52	4	.	.	X
ajbspi-122364	52	5	hawkins	hawkins	PROPN
ajbspi-122364	52	6	bt	bt	PROPN
ajbspi-122364	52	7	,	,	PUNCT
ajbspi-122364	52	8	davis	davis	PROPN
ajbspi-122364	52	9	tp	tp	ADP
ajbspi-122364	52	10	the	the	DET
ajbspi-122364	52	11	blood	blood	NOUN
ajbspi-122364	52	12	-	-	PUNCT
ajbspi-122364	52	13	brain	brain	NOUN
ajbspi-122364	52	14	barrier	barrier	NOUN
ajbspi-122364	52	15	/	/	SYM
ajbspi-122364	52	16	neurovascular	neurovascular	ADJ
ajbspi-122364	52	17	unit	unit	NOUN
ajbspi-122364	52	18	in	in	ADP
ajbspi-122364	52	19	health	health	NOUN
ajbspi-122364	52	20	and	and	CCONJ
ajbspi-122364	52	21	disease	disease	NOUN
ajbspi-122364	52	22	.	.	PUNCT
ajbspi-122364	53	1	pharmacological	pharmacological	ADJ
ajbspi-122364	53	2	reviews	review	NOUN
ajbspi-122364	53	3	.	.	PUNCT
ajbspi-122364	54	1	2005;57(2):173	2005;57(2):173	NUM
ajbspi-122364	54	2	-	-	SYM
ajbspi-122364	54	3	185	185	NUM
ajbspi-122364	54	4	.	.	PUNCT
ajbspi-122364	54	5	8	8	NUM
ajbspi-122364	54	6	.	.	X
ajbspi-122364	55	1	persidsky	persidsky	PROPN
ajbspi-122364	55	2	y.	y.	PROPN
ajbspi-122364	55	3	,	,	PUNCT
ajbspi-122364	55	4	ramirez	ramirez	PROPN
ajbspi-122364	55	5	sh	sh	PROPN
ajbspi-122364	55	6	,	,	PUNCT
ajbspi-122364	55	7	haorah	haorah	PROPN
ajbspi-122364	55	8	j.	j.	PROPN
ajbspi-122364	55	9	,	,	PUNCT
ajbspi-122364	55	10	kanmogne	kanmogne	VERB
ajbspi-122364	55	11	gd	gd	ADP
ajbspi-122364	55	12	blood	blood	NOUN
ajbspi-122364	55	13	-	-	PUNCT
ajbspi-122364	55	14	brain	brain	NOUN
ajbspi-122364	55	15	barrier	barrier	NOUN
ajbspi-122364	55	16	:	:	PUNCT
ajbspi-122364	55	17	structural	structural	ADJ
ajbspi-122364	55	18	components	component	NOUN
ajbspi-122364	55	19	and	and	CCONJ
ajbspi-122364	55	20	function	function	NOUN
ajbspi-122364	55	21	under	under	ADP
ajbspi-122364	55	22	physiologic	physiologic	ADJ
ajbspi-122364	55	23	and	and	CCONJ
ajbspi-122364	55	24	pathologic	pathologic	ADJ
ajbspi-122364	55	25	conditions	condition	NOUN
ajbspi-122364	55	26	.	.	PUNCT
ajbspi-122364	56	1	journal	journal	NOUN
ajbspi-122364	56	2	of	of	ADP
ajbspi-122364	56	3	neuroimmune	neuroimmune	PROPN
ajbspi-122364	56	4	pharmacology	pharmacology	NOUN
ajbspi-122364	56	5	.	.	PUNCT
ajbspi-122364	57	1	2006;1(3):223	2006;1(3):223	NUM
ajbspi-122364	57	2	-	-	SYM
ajbspi-122364	57	3	236	236	NUM
ajbspi-122364	57	4	.	.	PUNCT
ajbspi-122364	58	1	american	american	PROPN
ajbspi-122364	58	2	journal	journal	PROPN
ajbspi-122364	58	3	of	of	ADP
ajbspi-122364	58	4	applied	apply	VERB
ajbspi-122364	58	5	science	science	NOUN
ajbspi-122364	58	6	and	and	CCONJ
ajbspi-122364	58	7	technology	technology	NOUN
ajbspi-122364	58	8	27	27	NUM
ajbspi-122364	58	9	https://theusajournals.com/index.php/ajast	https://theusajournals.com/index.php/ajast	NOUN
ajbspi-122364	58	10	american	american	PROPN
ajbspi-122364	58	11	journal	journal	PROPN
ajbspi-122364	58	12	of	of	ADP
ajbspi-122364	58	13	applied	apply	VERB
ajbspi-122364	58	14	science	science	NOUN
ajbspi-122364	58	15	and	and	CCONJ
ajbspi-122364	58	16	technology	technology	NOUN
ajbspi-122364	58	17	(	(	PUNCT
ajbspi-122364	58	18	issn	issn	PROPN
ajbspi-122364	58	19	:	:	PUNCT
ajbspi-122364	58	20	2771	2771	NUM
ajbspi-122364	58	21	-	-	SYM
ajbspi-122364	58	22	2745	2745	NUM
ajbspi-122364	58	23	)	)	PUNCT
ajbspi-122364	58	24	9	9	NUM
ajbspi-122364	58	25	.	.	X
ajbspi-122364	58	26	daneman	daneman	NOUN
ajbspi-122364	58	27	r.	r.	PROPN
ajbspi-122364	58	28	the	the	DET
ajbspi-122364	58	29	blood	blood	NOUN
ajbspi-122364	58	30	–	–	PUNCT
ajbspi-122364	58	31	brain	brain	NOUN
ajbspi-122364	58	32	barrier	barrier	NOUN
ajbspi-122364	58	33	in	in	ADP
ajbspi-122364	58	34	health	health	NOUN
ajbspi-122364	58	35	and	and	CCONJ
ajbspi-122364	58	36	disease	disease	NOUN
ajbspi-122364	58	37	.	.	PUNCT
ajbspi-122364	59	1	annals	annal	NOUN
ajbspi-122364	59	2	of	of	ADP
ajbspi-122364	59	3	neurology	neurology	NOUN
ajbspi-122364	59	4	.	.	PUNCT
ajbspi-122364	60	1	2012;72(5):648	2012;72(5):648	NUM
ajbspi-122364	60	2	-	-	PUNCT
ajbspi-122364	60	3	672	672	NUM
ajbspi-122364	60	4	.	.	PUNCT
ajbspi-122364	61	1	10	10	NUM
ajbspi-122364	61	2	.	.	PUNCT
ajbspi-122364	62	1	hawkins	hawkins	PROPN
ajbspi-122364	62	2	bt	bt	PROPN
ajbspi-122364	62	3	,	,	PUNCT
ajbspi-122364	62	4	o'kane	o'kane	PROPN
ajbspi-122364	62	5	rl	rl	NOUN
ajbspi-122364	62	6	,	,	PUNCT
ajbspi-122364	62	7	meinig	meinig	NOUN
ajbspi-122364	62	8	rp	rp	NOUN
ajbspi-122364	62	9	,	,	PUNCT
ajbspi-122364	62	10	davis	davis	PROPN
ajbspi-122364	62	11	tp	tp	VERB
ajbspi-122364	62	12	contributions	contribution	NOUN
ajbspi-122364	62	13	of	of	ADP
ajbspi-122364	62	14	the	the	DET
ajbspi-122364	62	15	blood	blood	NOUN
ajbspi-122364	62	16	-	-	PUNCT
ajbspi-122364	62	17	brain	brain	NOUN
ajbspi-122364	62	18	barrier	barrier	NOUN
ajbspi-122364	62	19	to	to	ADP
ajbspi-122364	62	20	pharmacokinetics	pharmacokinetic	NOUN
ajbspi-122364	62	21	and	and	CCONJ
ajbspi-122364	62	22	pharmacodynamics	pharmacodynamic	NOUN
ajbspi-122364	62	23	of	of	ADP
ajbspi-122364	62	24	central	central	ADJ
ajbspi-122364	62	25	nervous	nervous	ADJ
ajbspi-122364	62	26	system	system	NOUN
ajbspi-122364	62	27	drugs	drug	NOUN
ajbspi-122364	62	28	.	.	PUNCT
ajbspi-122364	63	1	journal	journal	NOUN
ajbspi-122364	63	2	of	of	ADP
ajbspi-122364	63	3	pharmaceutical	pharmaceutical	NOUN
ajbspi-122364	63	4	sciences	science	NOUN
ajbspi-122364	63	5	.	.	PUNCT
ajbspi-122364	64	1	2007;96(10):2547	2007;96(10):2547	X
ajbspi-122364	64	2	-	-	PUNCT
ajbspi-122364	64	3	2561	2561	NUM
ajbspi-122364	64	4	.	.	PUNCT