id	sid	tid	token	lemma	pos
ajbspi-37615	1	1	volume	volume	NOUN
ajbspi-37615	1	2	03	03	NUM
ajbspi-37615	1	3	issue	issue	NOUN
ajbspi-37615	1	4	08	08	NUM
ajbspi-37615	1	5	-	-	SYM
ajbspi-37615	1	6	2023	2023	NUM
ajbspi-37615	1	7	10	10	NUM
ajbspi-37615	1	8	american	american	ADJ
ajbspi-37615	1	9	journal	journal	PROPN
ajbspi-37615	1	10	of	of	ADP
ajbspi-37615	1	11	biomedical	biomedical	PROPN
ajbspi-37615	1	12	science	science	PROPN
ajbspi-37615	1	13	&	&	CCONJ
ajbspi-37615	1	14	pharmaceutical	pharmaceutical	PROPN
ajbspi-37615	1	15	innovation	innovation	NOUN
ajbspi-37615	1	16	(	(	PUNCT
ajbspi-37615	1	17	issn	issn	PROPN
ajbspi-37615	1	18	–	–	PUNCT
ajbspi-37615	1	19	2771	2771	NUM
ajbspi-37615	1	20	-	-	SYM
ajbspi-37615	1	21	2753	2753	NUM
ajbspi-37615	1	22	)	)	PUNCT
ajbspi-37615	1	23	volume	volume	NOUN
ajbspi-37615	1	24	03	03	NUM
ajbspi-37615	1	25	issue	issue	NOUN
ajbspi-37615	1	26	08	08	NUM
ajbspi-37615	1	27	pages	page	NOUN
ajbspi-37615	1	28	:	:	PUNCT
ajbspi-37615	1	29	10	10	NUM
ajbspi-37615	1	30	-	-	SYM
ajbspi-37615	1	31	15	15	NUM
ajbspi-37615	1	32	sjif	sjif	NOUN
ajbspi-37615	1	33	impact	impact	NOUN
ajbspi-37615	1	34	factor	factor	NOUN
ajbspi-37615	1	35	(	(	PUNCT
ajbspi-37615	1	36	2021	2021	NUM
ajbspi-37615	1	37	:	:	PUNCT
ajbspi-37615	1	38	5	5	NUM
ajbspi-37615	1	39	.	.	NOUN
ajbspi-37615	1	40	705	705	NUM
ajbspi-37615	1	41	)	)	PUNCT
ajbspi-37615	1	42	(	(	PUNCT
ajbspi-37615	1	43	2022	2022	NUM
ajbspi-37615	1	44	:	:	PUNCT
ajbspi-37615	1	45	5	5	NUM
ajbspi-37615	1	46	.	.	NOUN
ajbspi-37615	1	47	705	705	NUM
ajbspi-37615	1	48	)	)	PUNCT
ajbspi-37615	1	49	(	(	PUNCT
ajbspi-37615	1	50	2023	2023	NUM
ajbspi-37615	1	51	:	:	PUNCT
ajbspi-37615	1	52	6.534	6.534	NUM
ajbspi-37615	1	53	)	)	PUNCT
ajbspi-37615	1	54	oclc	oclc	PROPN
ajbspi-37615	1	55	–	–	PUNCT
ajbspi-37615	1	56	1121105677	1121105677	NUM
ajbspi-37615	1	57	publisher	publisher	NOUN
ajbspi-37615	1	58	:	:	PUNCT
ajbspi-37615	1	59	oscar	oscar	NOUN
ajbspi-37615	1	60	publishing	publishing	NOUN
ajbspi-37615	1	61	services	service	NOUN
ajbspi-37615	1	62	servi	servi	PROPN
ajbspi-37615	1	63	abstract	abstract	ADJ
ajbspi-37615	1	64	amide	amide	NOUN
ajbspi-37615	1	65	-	-	PUNCT
ajbspi-37615	1	66	based	base	VERB
ajbspi-37615	1	67	mutual	mutual	ADJ
ajbspi-37615	1	68	prodrugs	prodrug	NOUN
ajbspi-37615	1	69	have	have	AUX
ajbspi-37615	1	70	gained	gain	VERB
ajbspi-37615	1	71	significant	significant	ADJ
ajbspi-37615	1	72	attention	attention	NOUN
ajbspi-37615	1	73	in	in	ADP
ajbspi-37615	1	74	recent	recent	ADJ
ajbspi-37615	1	75	years	year	NOUN
ajbspi-37615	1	76	as	as	ADP
ajbspi-37615	1	77	promising	promise	VERB
ajbspi-37615	1	78	pharmaceutical	pharmaceutical	ADJ
ajbspi-37615	1	79	candidates	candidate	NOUN
ajbspi-37615	1	80	due	due	ADP
ajbspi-37615	1	81	to	to	ADP
ajbspi-37615	1	82	their	their	PRON
ajbspi-37615	1	83	potential	potential	NOUN
ajbspi-37615	1	84	to	to	PART
ajbspi-37615	1	85	enhance	enhance	VERB
ajbspi-37615	1	86	drug	drug	NOUN
ajbspi-37615	1	87	solubility	solubility	NOUN
ajbspi-37615	1	88	,	,	PUNCT
ajbspi-37615	1	89	stability	stability	NOUN
ajbspi-37615	1	90	,	,	PUNCT
ajbspi-37615	1	91	and	and	CCONJ
ajbspi-37615	1	92	bioavailability	bioavailability	NOUN
ajbspi-37615	1	93	.	.	PUNCT
ajbspi-37615	2	1	this	this	DET
ajbspi-37615	2	2	study	study	NOUN
ajbspi-37615	2	3	focuses	focus	VERB
ajbspi-37615	2	4	on	on	ADP
ajbspi-37615	2	5	the	the	DET
ajbspi-37615	2	6	synthesis	synthesis	NOUN
ajbspi-37615	2	7	and	and	CCONJ
ajbspi-37615	2	8	evaluation	evaluation	NOUN
ajbspi-37615	2	9	of	of	ADP
ajbspi-37615	2	10	a	a	DET
ajbspi-37615	2	11	novel	novel	ADJ
ajbspi-37615	2	12	amide	amide	NOUN
ajbspi-37615	2	13	-	-	PUNCT
ajbspi-37615	2	14	based	base	VERB
ajbspi-37615	2	15	mutual	mutual	ADJ
ajbspi-37615	2	16	prodrug	prodrug	NOUN
ajbspi-37615	2	17	designed	design	VERB
ajbspi-37615	2	18	to	to	PART
ajbspi-37615	2	19	improve	improve	VERB
ajbspi-37615	2	20	the	the	DET
ajbspi-37615	2	21	delivery	delivery	NOUN
ajbspi-37615	2	22	and	and	CCONJ
ajbspi-37615	2	23	therapeutic	therapeutic	ADJ
ajbspi-37615	2	24	efficacy	efficacy	NOUN
ajbspi-37615	2	25	of	of	ADP
ajbspi-37615	2	26	a	a	DET
ajbspi-37615	2	27	parent	parent	NOUN
ajbspi-37615	2	28	drug	drug	NOUN
ajbspi-37615	2	29	.	.	PUNCT
ajbspi-37615	3	1	the	the	DET
ajbspi-37615	3	2	synthesis	synthesis	NOUN
ajbspi-37615	3	3	involves	involve	VERB
ajbspi-37615	3	4	the	the	DET
ajbspi-37615	3	5	chemical	chemical	ADJ
ajbspi-37615	3	6	conjugation	conjugation	NOUN
ajbspi-37615	3	7	of	of	ADP
ajbspi-37615	3	8	two	two	NUM
ajbspi-37615	3	9	active	active	ADJ
ajbspi-37615	3	10	moieties	moiety	NOUN
ajbspi-37615	3	11	through	through	ADP
ajbspi-37615	3	12	an	an	DET
ajbspi-37615	3	13	amide	amide	NOUN
ajbspi-37615	3	14	bond	bond	NOUN
ajbspi-37615	3	15	to	to	PART
ajbspi-37615	3	16	form	form	VERB
ajbspi-37615	3	17	a	a	DET
ajbspi-37615	3	18	single	single	ADJ
ajbspi-37615	3	19	prodrug	prodrug	NOUN
ajbspi-37615	3	20	entity	entity	NOUN
ajbspi-37615	3	21	.	.	PUNCT
ajbspi-37615	4	1	the	the	DET
ajbspi-37615	4	2	evaluation	evaluation	NOUN
ajbspi-37615	4	3	encompasses	encompass	VERB
ajbspi-37615	4	4	a	a	DET
ajbspi-37615	4	5	comprehensive	comprehensive	ADJ
ajbspi-37615	4	6	assessment	assessment	NOUN
ajbspi-37615	4	7	of	of	ADP
ajbspi-37615	4	8	physicochemical	physicochemical	ADJ
ajbspi-37615	4	9	properties	property	NOUN
ajbspi-37615	4	10	,	,	PUNCT
ajbspi-37615	4	11	in	in	ADP
ajbspi-37615	4	12	vitro	vitro	X
ajbspi-37615	4	13	release	release	NOUN
ajbspi-37615	4	14	kinetics	kinetic	NOUN
ajbspi-37615	4	15	,	,	PUNCT
ajbspi-37615	4	16	enzymatic	enzymatic	ADJ
ajbspi-37615	4	17	hydrolysis	hydrolysis	NOUN
ajbspi-37615	4	18	,	,	PUNCT
ajbspi-37615	4	19	and	and	CCONJ
ajbspi-37615	4	20	pharmacological	pharmacological	ADJ
ajbspi-37615	4	21	activity	activity	NOUN
ajbspi-37615	4	22	of	of	ADP
ajbspi-37615	4	23	the	the	DET
ajbspi-37615	4	24	prodrug	prodrug	NOUN
ajbspi-37615	4	25	compared	compare	VERB
ajbspi-37615	4	26	to	to	ADP
ajbspi-37615	4	27	the	the	DET
ajbspi-37615	4	28	parent	parent	NOUN
ajbspi-37615	4	29	drug	drug	NOUN
ajbspi-37615	4	30	.	.	PUNCT
ajbspi-37615	5	1	the	the	DET
ajbspi-37615	5	2	results	result	NOUN
ajbspi-37615	5	3	obtained	obtain	VERB
ajbspi-37615	5	4	shed	shed	VERB
ajbspi-37615	5	5	light	light	NOUN
ajbspi-37615	5	6	on	on	ADP
ajbspi-37615	5	7	the	the	DET
ajbspi-37615	5	8	prodrug	prodrug	NOUN
ajbspi-37615	5	9	's	's	PART
ajbspi-37615	5	10	potential	potential	ADJ
ajbspi-37615	5	11	advantages	advantage	NOUN
ajbspi-37615	5	12	and	and	CCONJ
ajbspi-37615	5	13	challenges	challenge	NOUN
ajbspi-37615	5	14	,	,	PUNCT
ajbspi-37615	5	15	providing	provide	VERB
ajbspi-37615	5	16	valuable	valuable	ADJ
ajbspi-37615	5	17	insights	insight	NOUN
ajbspi-37615	5	18	for	for	ADP
ajbspi-37615	5	19	further	further	ADJ
ajbspi-37615	5	20	optimization	optimization	NOUN
ajbspi-37615	5	21	and	and	CCONJ
ajbspi-37615	5	22	development	development	NOUN
ajbspi-37615	5	23	.	.	PUNCT
ajbspi-37615	6	1	the	the	DET
ajbspi-37615	6	2	findings	finding	NOUN
ajbspi-37615	6	3	of	of	ADP
ajbspi-37615	6	4	this	this	DET
ajbspi-37615	6	5	study	study	NOUN
ajbspi-37615	6	6	contribute	contribute	VERB
ajbspi-37615	6	7	to	to	ADP
ajbspi-37615	6	8	the	the	DET
ajbspi-37615	6	9	growing	grow	VERB
ajbspi-37615	6	10	body	body	NOUN
ajbspi-37615	6	11	of	of	ADP
ajbspi-37615	6	12	knowledge	knowledge	NOUN
ajbspi-37615	6	13	on	on	ADP
ajbspi-37615	6	14	amide	amide	NOUN
ajbspi-37615	6	15	-	-	PUNCT
ajbspi-37615	6	16	based	base	VERB
ajbspi-37615	6	17	mutual	mutual	ADJ
ajbspi-37615	6	18	prodrugs	prodrug	NOUN
ajbspi-37615	6	19	and	and	CCONJ
ajbspi-37615	6	20	their	their	PRON
ajbspi-37615	6	21	application	application	NOUN
ajbspi-37615	6	22	in	in	ADP
ajbspi-37615	6	23	pharmaceutical	pharmaceutical	ADJ
ajbspi-37615	6	24	research	research	NOUN
ajbspi-37615	6	25	.	.	PUNCT
ajbspi-37615	7	1	keywords	keyword	VERB
ajbspi-37615	7	2	amide	amide	NOUN
ajbspi-37615	7	3	-	-	PUNCT
ajbspi-37615	7	4	based	base	VERB
ajbspi-37615	7	5	mutual	mutual	ADJ
ajbspi-37615	7	6	prodrug	prodrug	NOUN
ajbspi-37615	7	7	,	,	PUNCT
ajbspi-37615	7	8	synthesis	synthesis	NOUN
ajbspi-37615	7	9	,	,	PUNCT
ajbspi-37615	7	10	evaluation	evaluation	NOUN
ajbspi-37615	7	11	,	,	PUNCT
ajbspi-37615	7	12	drug	drug	NOUN
ajbspi-37615	7	13	delivery	delivery	NOUN
ajbspi-37615	7	14	,	,	PUNCT
ajbspi-37615	7	15	solubility	solubility	NOUN
ajbspi-37615	7	16	,	,	PUNCT
ajbspi-37615	7	17	stability	stability	NOUN
ajbspi-37615	7	18	,	,	PUNCT
ajbspi-37615	7	19	bioavailability	bioavailability	NOUN
ajbspi-37615	7	20	,	,	PUNCT
ajbspi-37615	7	21	physicochemical	physicochemical	ADJ
ajbspi-37615	7	22	properties	property	NOUN
ajbspi-37615	7	23	,	,	PUNCT
ajbspi-37615	7	24	in	in	ADP
ajbspi-37615	7	25	vitro	vitro	X
ajbspi-37615	7	26	release	release	NOUN
ajbspi-37615	7	27	kinetics	kinetic	NOUN
ajbspi-37615	7	28	,	,	PUNCT
ajbspi-37615	7	29	enzymatic	enzymatic	ADJ
ajbspi-37615	7	30	hydrolysis	hydrolysis	NOUN
ajbspi-37615	7	31	,	,	PUNCT
ajbspi-37615	7	32	pharmacological	pharmacological	ADJ
ajbspi-37615	7	33	activity	activity	NOUN
ajbspi-37615	7	34	,	,	PUNCT
ajbspi-37615	7	35	pharmaceutical	pharmaceutical	NOUN
ajbspi-37615	7	36	research	research	NOUN
ajbspi-37615	7	37	.	.	PUNCT
ajbspi-37615	8	1	introduction	introduction	NOUN
ajbspi-37615	8	2	research	research	NOUN
ajbspi-37615	8	3	article	article	NOUN
ajbspi-37615	8	4	amide	amide	NOUN
ajbspi-37615	8	5	-	-	PUNCT
ajbspi-37615	8	6	based	base	VERB
ajbspi-37615	8	7	mutual	mutual	ADJ
ajbspi-37615	8	8	prodrug	prodrug	NOUN
ajbspi-37615	8	9	:	:	PUNCT
ajbspi-37615	8	10	synthesis	synthesis	NOUN
ajbspi-37615	8	11	and	and	CCONJ
ajbspi-37615	8	12	evaluation	evaluation	NOUN
ajbspi-37615	8	13	studies	study	NOUN
ajbspi-37615	8	14	submission	submission	NOUN
ajbspi-37615	8	15	date	date	NOUN
ajbspi-37615	8	16	:	:	PUNCT
ajbspi-37615	8	17	aug	aug	PROPN
ajbspi-37615	8	18	02	02	NUM
ajbspi-37615	8	19	,	,	PUNCT
ajbspi-37615	8	20	2023	2023	NUM
ajbspi-37615	8	21	,	,	PUNCT
ajbspi-37615	8	22	accepted	accept	VERB
ajbspi-37615	8	23	date	date	NOUN
ajbspi-37615	8	24	:	:	PUNCT
ajbspi-37615	8	25	aug	aug	PROPN
ajbspi-37615	8	26	07	07	NUM
ajbspi-37615	8	27	,	,	PUNCT
ajbspi-37615	8	28	2023	2023	NUM
ajbspi-37615	8	29	,	,	PUNCT
ajbspi-37615	8	30	published	publish	VERB
ajbspi-37615	8	31	date	date	NOUN
ajbspi-37615	8	32	:	:	PUNCT
ajbspi-37615	8	33	aug	aug	PROPN
ajbspi-37615	8	34	12	12	NUM
ajbspi-37615	8	35	,	,	PUNCT
ajbspi-37615	8	36	2023	2023	NUM
ajbspi-37615	8	37	crossref	crossref	NOUN
ajbspi-37615	8	38	doi	doi	NOUN
ajbspi-37615	8	39	:	:	PUNCT
ajbspi-37615	8	40	https://doi.org/10.37547/ajbspi/volume03issue08-03	https://doi.org/10.37547/ajbspi/volume03issue08-03	PROPN
ajbspi-37615	8	41	aftab	aftab	PROPN
ajbspi-37615	8	42	alam	alam	PROPN
ajbspi-37615	8	43	department	department	PROPN
ajbspi-37615	8	44	of	of	ADP
ajbspi-37615	8	45	pharmaceutical	pharmaceutical	ADJ
ajbspi-37615	8	46	chemistry	chemistry	NOUN
ajbspi-37615	8	47	,	,	PUNCT
ajbspi-37615	8	48	king	king	NOUN
ajbspi-37615	8	49	abdul	abdul	PROPN
ajbspi-37615	8	50	aziz	aziz	PROPN
ajbspi-37615	8	51	university	university	PROPN
ajbspi-37615	8	52	,	,	PUNCT
ajbspi-37615	8	53	jeddah	jeddah	PROPN
ajbspi-37615	8	54	21589	21589	NUM
ajbspi-37615	8	55	,	,	PUNCT
ajbspi-37615	8	56	kingdom	kingdom	NOUN
ajbspi-37615	8	57	of	of	ADP
ajbspi-37615	8	58	saudi	saudi	PROPN
ajbspi-37615	8	59	arabia	arabia	PROPN
ajbspi-37615	8	60	journal	journal	PROPN
ajbspi-37615	8	61	website	website	NOUN
ajbspi-37615	8	62	:	:	PUNCT
ajbspi-37615	8	63	https://theusajournals	https://theusajournals	PROPN
ajbspi-37615	8	64	.	.	PUNCT
ajbspi-37615	8	65	com	com	NOUN
ajbspi-37615	8	66	/	/	SYM
ajbspi-37615	8	67	index.php	index.php	VERB
ajbspi-37615	8	68	/	/	SYM
ajbspi-37615	8	69	ajbspi	ajbspi	NOUN
ajbspi-37615	8	70	copyright	copyright	NOUN
ajbspi-37615	8	71	:	:	PUNCT
ajbspi-37615	8	72	original	original	ADJ
ajbspi-37615	8	73	content	content	NOUN
ajbspi-37615	8	74	from	from	ADP
ajbspi-37615	8	75	this	this	DET
ajbspi-37615	8	76	work	work	NOUN
ajbspi-37615	8	77	may	may	AUX
ajbspi-37615	8	78	be	be	AUX
ajbspi-37615	8	79	used	use	VERB
ajbspi-37615	8	80	under	under	ADP
ajbspi-37615	8	81	the	the	DET
ajbspi-37615	8	82	terms	term	NOUN
ajbspi-37615	8	83	of	of	ADP
ajbspi-37615	8	84	the	the	DET
ajbspi-37615	8	85	creative	creative	ADJ
ajbspi-37615	8	86	commons	common	NOUN
ajbspi-37615	8	87	attributes	attribute	VERB
ajbspi-37615	8	88	4.0	4.0	NUM
ajbspi-37615	8	89	licence	licence	NOUN
ajbspi-37615	8	90	.	.	PUNCT
ajbspi-37615	9	1	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	PROPN
ajbspi-37615	9	2	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	AUX
ajbspi-37615	9	3	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	PROPN
ajbspi-37615	9	4	https://theusajournals.com/	https://theusajournals.com/	PROPN
ajbspi-37615	9	5	https://doi.org/10.37547/ajbspi/volume03issue08-03	https://doi.org/10.37547/ajbspi/volume03issue08-03	NOUN
ajbspi-37615	9	6	https://doi.org/10.37547/ajbspi/volume03issue08-03	https://doi.org/10.37547/ajbspi/volume03issue08-03	PRON
ajbspi-37615	9	7	https://theusajournals.com/index.php/ajbspi	https://theusajournals.com/index.php/ajbspi	NOUN
ajbspi-37615	9	8	https://theusajournals.com/index.php/ajbspi	https://theusajournals.com/index.php/ajbspi	NOUN
ajbspi-37615	9	9	https://theusajournals.com/index.php/ajbspi	https://theusajournals.com/index.php/ajbspi	NOUN
ajbspi-37615	10	1	https://theusajournals.com/index.php/ajbspi	https://theusajournals.com/index.php/ajbspi	NOUN
ajbspi-37615	10	2	volume	volume	NOUN
ajbspi-37615	10	3	03	03	NUM
ajbspi-37615	10	4	issue	issue	NOUN
ajbspi-37615	10	5	08	08	NUM
ajbspi-37615	10	6	-	-	SYM
ajbspi-37615	10	7	2023	2023	NUM
ajbspi-37615	10	8	11	11	NUM
ajbspi-37615	10	9	american	american	ADJ
ajbspi-37615	10	10	journal	journal	PROPN
ajbspi-37615	10	11	of	of	ADP
ajbspi-37615	10	12	biomedical	biomedical	PROPN
ajbspi-37615	10	13	science	science	PROPN
ajbspi-37615	10	14	&	&	CCONJ
ajbspi-37615	10	15	pharmaceutical	pharmaceutical	PROPN
ajbspi-37615	10	16	innovation	innovation	NOUN
ajbspi-37615	10	17	(	(	PUNCT
ajbspi-37615	10	18	issn	issn	PROPN
ajbspi-37615	10	19	–	–	PUNCT
ajbspi-37615	10	20	2771	2771	NUM
ajbspi-37615	10	21	-	-	SYM
ajbspi-37615	10	22	2753	2753	NUM
ajbspi-37615	10	23	)	)	PUNCT
ajbspi-37615	10	24	volume	volume	NOUN
ajbspi-37615	10	25	03	03	NUM
ajbspi-37615	10	26	issue	issue	NOUN
ajbspi-37615	10	27	08	08	NUM
ajbspi-37615	10	28	pages	page	NOUN
ajbspi-37615	10	29	:	:	PUNCT
ajbspi-37615	10	30	10	10	NUM
ajbspi-37615	10	31	-	-	SYM
ajbspi-37615	10	32	15	15	NUM
ajbspi-37615	10	33	sjif	sjif	NOUN
ajbspi-37615	10	34	impact	impact	NOUN
ajbspi-37615	10	35	factor	factor	NOUN
ajbspi-37615	10	36	(	(	PUNCT
ajbspi-37615	10	37	2021	2021	NUM
ajbspi-37615	10	38	:	:	PUNCT
ajbspi-37615	10	39	5	5	NUM
ajbspi-37615	10	40	.	.	NOUN
ajbspi-37615	10	41	705	705	NUM
ajbspi-37615	10	42	)	)	PUNCT
ajbspi-37615	10	43	(	(	PUNCT
ajbspi-37615	10	44	2022	2022	NUM
ajbspi-37615	10	45	:	:	PUNCT
ajbspi-37615	10	46	5	5	NUM
ajbspi-37615	10	47	.	.	NOUN
ajbspi-37615	10	48	705	705	NUM
ajbspi-37615	10	49	)	)	PUNCT
ajbspi-37615	10	50	(	(	PUNCT
ajbspi-37615	10	51	2023	2023	NUM
ajbspi-37615	10	52	:	:	PUNCT
ajbspi-37615	10	53	6.534	6.534	NUM
ajbspi-37615	10	54	)	)	PUNCT
ajbspi-37615	10	55	oclc	oclc	PROPN
ajbspi-37615	10	56	–	–	PUNCT
ajbspi-37615	10	57	1121105677	1121105677	NUM
ajbspi-37615	10	58	publisher	publisher	NOUN
ajbspi-37615	10	59	:	:	PUNCT
ajbspi-37615	10	60	oscar	oscar	NOUN
ajbspi-37615	10	61	publishing	publishing	NOUN
ajbspi-37615	10	62	services	service	NOUN
ajbspi-37615	10	63	servi	servi	VERB
ajbspi-37615	10	64	in	in	ADP
ajbspi-37615	10	65	the	the	DET
ajbspi-37615	10	66	field	field	NOUN
ajbspi-37615	10	67	of	of	ADP
ajbspi-37615	10	68	pharmaceutical	pharmaceutical	ADJ
ajbspi-37615	10	69	research	research	NOUN
ajbspi-37615	10	70	,	,	PUNCT
ajbspi-37615	10	71	the	the	DET
ajbspi-37615	10	72	design	design	NOUN
ajbspi-37615	10	73	and	and	CCONJ
ajbspi-37615	10	74	development	development	NOUN
ajbspi-37615	10	75	of	of	ADP
ajbspi-37615	10	76	novel	novel	ADJ
ajbspi-37615	10	77	drug	drug	NOUN
ajbspi-37615	10	78	delivery	delivery	NOUN
ajbspi-37615	10	79	systems	system	NOUN
ajbspi-37615	10	80	have	have	AUX
ajbspi-37615	10	81	become	become	VERB
ajbspi-37615	10	82	paramount	paramount	ADJ
ajbspi-37615	10	83	to	to	PART
ajbspi-37615	10	84	overcome	overcome	VERB
ajbspi-37615	10	85	the	the	DET
ajbspi-37615	10	86	limitations	limitation	NOUN
ajbspi-37615	10	87	of	of	ADP
ajbspi-37615	10	88	conventional	conventional	ADJ
ajbspi-37615	10	89	therapeutics	therapeutic	NOUN
ajbspi-37615	10	90	.	.	PUNCT
ajbspi-37615	11	1	among	among	ADP
ajbspi-37615	11	2	various	various	ADJ
ajbspi-37615	11	3	strategies	strategy	NOUN
ajbspi-37615	11	4	,	,	PUNCT
ajbspi-37615	11	5	prodrug	prodrug	NOUN
ajbspi-37615	11	6	-	-	PUNCT
ajbspi-37615	11	7	based	base	VERB
ajbspi-37615	11	8	approaches	approach	NOUN
ajbspi-37615	11	9	have	have	AUX
ajbspi-37615	11	10	emerged	emerge	VERB
ajbspi-37615	11	11	as	as	ADP
ajbspi-37615	11	12	promising	promise	VERB
ajbspi-37615	11	13	solutions	solution	NOUN
ajbspi-37615	11	14	to	to	PART
ajbspi-37615	11	15	improve	improve	VERB
ajbspi-37615	11	16	drug	drug	NOUN
ajbspi-37615	11	17	solubility	solubility	NOUN
ajbspi-37615	11	18	,	,	PUNCT
ajbspi-37615	11	19	stability	stability	NOUN
ajbspi-37615	11	20	,	,	PUNCT
ajbspi-37615	11	21	and	and	CCONJ
ajbspi-37615	11	22	bioavailability	bioavailability	NOUN
ajbspi-37615	11	23	,	,	PUNCT
ajbspi-37615	11	24	leading	lead	VERB
ajbspi-37615	11	25	to	to	ADP
ajbspi-37615	11	26	enhanced	enhance	VERB
ajbspi-37615	11	27	therapeutic	therapeutic	ADJ
ajbspi-37615	11	28	efficacy	efficacy	NOUN
ajbspi-37615	11	29	and	and	CCONJ
ajbspi-37615	11	30	patient	patient	ADJ
ajbspi-37615	11	31	compliance	compliance	NOUN
ajbspi-37615	11	32	.	.	PUNCT
ajbspi-37615	12	1	among	among	ADP
ajbspi-37615	12	2	these	these	PRON
ajbspi-37615	12	3	,	,	PUNCT
ajbspi-37615	12	4	amide	amide	NOUN
ajbspi-37615	12	5	-	-	PUNCT
ajbspi-37615	12	6	based	base	VERB
ajbspi-37615	12	7	mutual	mutual	ADJ
ajbspi-37615	12	8	prodrugs	prodrug	NOUN
ajbspi-37615	12	9	have	have	AUX
ajbspi-37615	12	10	attracted	attract	VERB
ajbspi-37615	12	11	considerable	considerable	ADJ
ajbspi-37615	12	12	attention	attention	NOUN
ajbspi-37615	12	13	due	due	ADP
ajbspi-37615	12	14	to	to	ADP
ajbspi-37615	12	15	their	their	PRON
ajbspi-37615	12	16	versatile	versatile	ADJ
ajbspi-37615	12	17	properties	property	NOUN
ajbspi-37615	12	18	and	and	CCONJ
ajbspi-37615	12	19	potential	potential	ADJ
ajbspi-37615	12	20	benefits	benefit	NOUN
ajbspi-37615	12	21	in	in	ADP
ajbspi-37615	12	22	drug	drug	NOUN
ajbspi-37615	12	23	delivery	delivery	NOUN
ajbspi-37615	12	24	.	.	PUNCT
ajbspi-37615	13	1	amide	amide	NOUN
ajbspi-37615	13	2	-	-	PUNCT
ajbspi-37615	13	3	based	base	VERB
ajbspi-37615	13	4	mutual	mutual	ADJ
ajbspi-37615	13	5	prodrugs	prodrug	NOUN
ajbspi-37615	13	6	involve	involve	VERB
ajbspi-37615	13	7	the	the	DET
ajbspi-37615	13	8	chemical	chemical	ADJ
ajbspi-37615	13	9	conjugation	conjugation	NOUN
ajbspi-37615	13	10	of	of	ADP
ajbspi-37615	13	11	two	two	NUM
ajbspi-37615	13	12	active	active	ADJ
ajbspi-37615	13	13	moieties	moiety	NOUN
ajbspi-37615	13	14	through	through	ADP
ajbspi-37615	13	15	an	an	DET
ajbspi-37615	13	16	amide	amide	NOUN
ajbspi-37615	13	17	bond	bond	NOUN
ajbspi-37615	13	18	,	,	PUNCT
ajbspi-37615	13	19	resulting	result	VERB
ajbspi-37615	13	20	in	in	ADP
ajbspi-37615	13	21	a	a	DET
ajbspi-37615	13	22	single	single	ADJ
ajbspi-37615	13	23	prodrug	prodrug	NOUN
ajbspi-37615	13	24	entity	entity	NOUN
ajbspi-37615	13	25	.	.	PUNCT
ajbspi-37615	14	1	this	this	DET
ajbspi-37615	14	2	conjugation	conjugation	NOUN
ajbspi-37615	14	3	can	can	AUX
ajbspi-37615	14	4	modify	modify	VERB
ajbspi-37615	14	5	the	the	DET
ajbspi-37615	14	6	physicochemical	physicochemical	ADJ
ajbspi-37615	14	7	properties	property	NOUN
ajbspi-37615	14	8	of	of	ADP
ajbspi-37615	14	9	the	the	DET
ajbspi-37615	14	10	parent	parent	NOUN
ajbspi-37615	14	11	drug	drug	NOUN
ajbspi-37615	14	12	,	,	PUNCT
ajbspi-37615	14	13	influencing	influence	VERB
ajbspi-37615	14	14	its	its	PRON
ajbspi-37615	14	15	pharmacokinetic	pharmacokinetic	ADJ
ajbspi-37615	14	16	profile	profile	NOUN
ajbspi-37615	14	17	and	and	CCONJ
ajbspi-37615	14	18	facilitating	facilitate	VERB
ajbspi-37615	14	19	targeted	target	VERB
ajbspi-37615	14	20	delivery	delivery	NOUN
ajbspi-37615	14	21	to	to	ADP
ajbspi-37615	14	22	specific	specific	ADJ
ajbspi-37615	14	23	sites	site	NOUN
ajbspi-37615	14	24	of	of	ADP
ajbspi-37615	14	25	action	action	NOUN
ajbspi-37615	14	26	.	.	PUNCT
ajbspi-37615	15	1	the	the	DET
ajbspi-37615	15	2	mutual	mutual	ADJ
ajbspi-37615	15	3	prodrug	prodrug	NOUN
ajbspi-37615	15	4	concept	concept	NOUN
ajbspi-37615	15	5	allows	allow	VERB
ajbspi-37615	15	6	for	for	ADP
ajbspi-37615	15	7	the	the	DET
ajbspi-37615	15	8	covalent	covalent	ADJ
ajbspi-37615	15	9	linkage	linkage	NOUN
ajbspi-37615	15	10	of	of	ADP
ajbspi-37615	15	11	two	two	NUM
ajbspi-37615	15	12	distinct	distinct	ADJ
ajbspi-37615	15	13	pharmacologically	pharmacologically	ADV
ajbspi-37615	15	14	active	active	ADJ
ajbspi-37615	15	15	compounds	compound	NOUN
ajbspi-37615	15	16	,	,	PUNCT
ajbspi-37615	15	17	offering	offer	VERB
ajbspi-37615	15	18	the	the	DET
ajbspi-37615	15	19	possibility	possibility	NOUN
ajbspi-37615	15	20	of	of	ADP
ajbspi-37615	15	21	synergistic	synergistic	ADJ
ajbspi-37615	15	22	effects	effect	NOUN
ajbspi-37615	15	23	or	or	CCONJ
ajbspi-37615	15	24	improved	improve	VERB
ajbspi-37615	15	25	therapeutic	therapeutic	ADJ
ajbspi-37615	15	26	actions	action	NOUN
ajbspi-37615	15	27	compared	compare	VERB
ajbspi-37615	15	28	to	to	ADP
ajbspi-37615	15	29	the	the	DET
ajbspi-37615	15	30	individual	individual	ADJ
ajbspi-37615	15	31	parent	parent	NOUN
ajbspi-37615	15	32	drugs	drug	NOUN
ajbspi-37615	15	33	.	.	PUNCT
ajbspi-37615	16	1	one	one	NUM
ajbspi-37615	16	2	of	of	ADP
ajbspi-37615	16	3	the	the	DET
ajbspi-37615	16	4	key	key	ADJ
ajbspi-37615	16	5	advantages	advantage	NOUN
ajbspi-37615	16	6	of	of	ADP
ajbspi-37615	16	7	amide	amide	NOUN
ajbspi-37615	16	8	-	-	PUNCT
ajbspi-37615	16	9	based	base	VERB
ajbspi-37615	16	10	mutual	mutual	ADJ
ajbspi-37615	16	11	prodrugs	prodrug	NOUN
ajbspi-37615	16	12	lies	lie	VERB
ajbspi-37615	16	13	in	in	ADP
ajbspi-37615	16	14	their	their	PRON
ajbspi-37615	16	15	ability	ability	NOUN
ajbspi-37615	16	16	to	to	PART
ajbspi-37615	16	17	increase	increase	VERB
ajbspi-37615	16	18	drug	drug	NOUN
ajbspi-37615	16	19	solubility	solubility	NOUN
ajbspi-37615	16	20	,	,	PUNCT
ajbspi-37615	16	21	which	which	PRON
ajbspi-37615	16	22	is	be	AUX
ajbspi-37615	16	23	a	a	DET
ajbspi-37615	16	24	critical	critical	ADJ
ajbspi-37615	16	25	factor	factor	NOUN
ajbspi-37615	16	26	in	in	ADP
ajbspi-37615	16	27	drug	drug	NOUN
ajbspi-37615	16	28	development	development	NOUN
ajbspi-37615	16	29	.	.	PUNCT
ajbspi-37615	17	1	poor	poor	ADJ
ajbspi-37615	17	2	solubility	solubility	NOUN
ajbspi-37615	17	3	often	often	ADV
ajbspi-37615	17	4	leads	lead	VERB
ajbspi-37615	17	5	to	to	ADP
ajbspi-37615	17	6	low	low	ADJ
ajbspi-37615	17	7	bioavailability	bioavailability	NOUN
ajbspi-37615	17	8	,	,	PUNCT
ajbspi-37615	17	9	limiting	limit	VERB
ajbspi-37615	17	10	the	the	DET
ajbspi-37615	17	11	therapeutic	therapeutic	ADJ
ajbspi-37615	17	12	potential	potential	NOUN
ajbspi-37615	17	13	of	of	ADP
ajbspi-37615	17	14	many	many	ADJ
ajbspi-37615	17	15	promising	promising	ADJ
ajbspi-37615	17	16	drug	drug	NOUN
ajbspi-37615	17	17	candidates	candidate	NOUN
ajbspi-37615	17	18	.	.	PUNCT
ajbspi-37615	18	1	by	by	ADP
ajbspi-37615	18	2	forming	form	VERB
ajbspi-37615	18	3	a	a	DET
ajbspi-37615	18	4	prodrug	prodrug	NOUN
ajbspi-37615	18	5	with	with	ADP
ajbspi-37615	18	6	improved	improve	VERB
ajbspi-37615	18	7	solubility	solubility	NOUN
ajbspi-37615	18	8	,	,	PUNCT
ajbspi-37615	18	9	the	the	DET
ajbspi-37615	18	10	dissolution	dissolution	NOUN
ajbspi-37615	18	11	rate	rate	NOUN
ajbspi-37615	18	12	and	and	CCONJ
ajbspi-37615	18	13	subsequent	subsequent	ADJ
ajbspi-37615	18	14	absorption	absorption	NOUN
ajbspi-37615	18	15	can	can	AUX
ajbspi-37615	18	16	be	be	AUX
ajbspi-37615	18	17	enhanced	enhance	VERB
ajbspi-37615	18	18	,	,	PUNCT
ajbspi-37615	18	19	leading	lead	VERB
ajbspi-37615	18	20	to	to	ADP
ajbspi-37615	18	21	more	more	ADV
ajbspi-37615	18	22	effective	effective	ADJ
ajbspi-37615	18	23	drug	drug	NOUN
ajbspi-37615	18	24	delivery	delivery	NOUN
ajbspi-37615	18	25	.	.	PUNCT
ajbspi-37615	19	1	moreover	moreover	ADV
ajbspi-37615	19	2	,	,	PUNCT
ajbspi-37615	19	3	mutual	mutual	ADJ
ajbspi-37615	19	4	prodrugs	prodrug	NOUN
ajbspi-37615	19	5	can	can	AUX
ajbspi-37615	19	6	protect	protect	VERB
ajbspi-37615	19	7	the	the	DET
ajbspi-37615	19	8	active	active	ADJ
ajbspi-37615	19	9	components	component	NOUN
ajbspi-37615	19	10	from	from	ADP
ajbspi-37615	19	11	rapid	rapid	ADJ
ajbspi-37615	19	12	metabolism	metabolism	NOUN
ajbspi-37615	19	13	or	or	CCONJ
ajbspi-37615	19	14	degradation	degradation	NOUN
ajbspi-37615	19	15	,	,	PUNCT
ajbspi-37615	19	16	extending	extend	VERB
ajbspi-37615	19	17	their	their	PRON
ajbspi-37615	19	18	systemic	systemic	ADJ
ajbspi-37615	19	19	circulation	circulation	NOUN
ajbspi-37615	19	20	time	time	NOUN
ajbspi-37615	19	21	.	.	PUNCT
ajbspi-37615	20	1	this	this	DET
ajbspi-37615	20	2	increased	increase	VERB
ajbspi-37615	20	3	stability	stability	NOUN
ajbspi-37615	20	4	may	may	AUX
ajbspi-37615	20	5	result	result	VERB
ajbspi-37615	20	6	in	in	ADP
ajbspi-37615	20	7	prolonged	prolonged	ADJ
ajbspi-37615	20	8	therapeutic	therapeutic	ADJ
ajbspi-37615	20	9	effects	effect	NOUN
ajbspi-37615	20	10	,	,	PUNCT
ajbspi-37615	20	11	reduced	reduce	VERB
ajbspi-37615	20	12	dosing	dose	VERB
ajbspi-37615	20	13	frequency	frequency	NOUN
ajbspi-37615	20	14	,	,	PUNCT
ajbspi-37615	20	15	and	and	CCONJ
ajbspi-37615	20	16	minimized	minimized	ADJ
ajbspi-37615	20	17	side	side	NOUN
ajbspi-37615	20	18	effects	effect	NOUN
ajbspi-37615	20	19	,	,	PUNCT
ajbspi-37615	20	20	thereby	thereby	ADV
ajbspi-37615	20	21	improving	improve	VERB
ajbspi-37615	20	22	patient	patient	ADJ
ajbspi-37615	20	23	compliance	compliance	NOUN
ajbspi-37615	20	24	and	and	CCONJ
ajbspi-37615	20	25	overall	overall	ADJ
ajbspi-37615	20	26	treatment	treatment	NOUN
ajbspi-37615	20	27	outcomes	outcome	NOUN
ajbspi-37615	20	28	.	.	PUNCT
ajbspi-37615	21	1	the	the	DET
ajbspi-37615	21	2	evaluation	evaluation	NOUN
ajbspi-37615	21	3	of	of	ADP
ajbspi-37615	21	4	amide	amide	NOUN
ajbspi-37615	21	5	-	-	PUNCT
ajbspi-37615	21	6	based	base	VERB
ajbspi-37615	21	7	mutual	mutual	ADJ
ajbspi-37615	21	8	prodrugs	prodrug	NOUN
ajbspi-37615	21	9	involves	involve	VERB
ajbspi-37615	21	10	a	a	DET
ajbspi-37615	21	11	comprehensive	comprehensive	ADJ
ajbspi-37615	21	12	assessment	assessment	NOUN
ajbspi-37615	21	13	of	of	ADP
ajbspi-37615	21	14	various	various	ADJ
ajbspi-37615	21	15	parameters	parameter	NOUN
ajbspi-37615	21	16	,	,	PUNCT
ajbspi-37615	21	17	including	include	VERB
ajbspi-37615	21	18	physicochemical	physicochemical	ADJ
ajbspi-37615	21	19	properties	property	NOUN
ajbspi-37615	21	20	,	,	PUNCT
ajbspi-37615	21	21	in	in	ADP
ajbspi-37615	21	22	vitro	vitro	X
ajbspi-37615	21	23	release	release	NOUN
ajbspi-37615	21	24	kinetics	kinetic	NOUN
ajbspi-37615	21	25	,	,	PUNCT
ajbspi-37615	21	26	enzymatic	enzymatic	ADJ
ajbspi-37615	21	27	hydrolysis	hydrolysis	NOUN
ajbspi-37615	21	28	,	,	PUNCT
ajbspi-37615	21	29	and	and	CCONJ
ajbspi-37615	21	30	pharmacological	pharmacological	ADJ
ajbspi-37615	21	31	activity	activity	NOUN
ajbspi-37615	21	32	.	.	PUNCT
ajbspi-37615	22	1	these	these	DET
ajbspi-37615	22	2	studies	study	NOUN
ajbspi-37615	22	3	are	be	AUX
ajbspi-37615	22	4	essential	essential	ADJ
ajbspi-37615	22	5	to	to	PART
ajbspi-37615	22	6	understand	understand	VERB
ajbspi-37615	22	7	the	the	DET
ajbspi-37615	22	8	prodrug	prodrug	NOUN
ajbspi-37615	22	9	's	's	PART
ajbspi-37615	22	10	behavior	behavior	NOUN
ajbspi-37615	22	11	and	and	CCONJ
ajbspi-37615	22	12	predict	predict	VERB
ajbspi-37615	22	13	its	its	PRON
ajbspi-37615	22	14	performance	performance	NOUN
ajbspi-37615	22	15	in	in	ADP
ajbspi-37615	22	16	vivo	vivo	NOUN
ajbspi-37615	22	17	.	.	PUNCT
ajbspi-37615	23	1	furthermore	furthermore	ADV
ajbspi-37615	23	2	,	,	PUNCT
ajbspi-37615	23	3	characterizing	characterize	VERB
ajbspi-37615	23	4	the	the	DET
ajbspi-37615	23	5	enzymatic	enzymatic	ADJ
ajbspi-37615	23	6	hydrolysis	hydrolysis	NOUN
ajbspi-37615	23	7	of	of	ADP
ajbspi-37615	23	8	the	the	DET
ajbspi-37615	23	9	amide	amide	NOUN
ajbspi-37615	23	10	bond	bond	NOUN
ajbspi-37615	23	11	aids	aid	NOUN
ajbspi-37615	23	12	in	in	ADP
ajbspi-37615	23	13	understanding	understand	VERB
ajbspi-37615	23	14	the	the	DET
ajbspi-37615	23	15	drug	drug	NOUN
ajbspi-37615	23	16	release	release	NOUN
ajbspi-37615	23	17	mechanism	mechanism	NOUN
ajbspi-37615	23	18	and	and	CCONJ
ajbspi-37615	23	19	the	the	DET
ajbspi-37615	23	20	potential	potential	NOUN
ajbspi-37615	23	21	for	for	ADP
ajbspi-37615	23	22	controlled	control	VERB
ajbspi-37615	23	23	drug	drug	NOUN
ajbspi-37615	23	24	delivery	delivery	NOUN
ajbspi-37615	23	25	.	.	PUNCT
ajbspi-37615	24	1	in	in	ADP
ajbspi-37615	24	2	this	this	DET
ajbspi-37615	24	3	context	context	NOUN
ajbspi-37615	24	4	,	,	PUNCT
ajbspi-37615	24	5	the	the	DET
ajbspi-37615	24	6	present	present	ADJ
ajbspi-37615	24	7	study	study	NOUN
ajbspi-37615	24	8	aims	aim	VERB
ajbspi-37615	24	9	to	to	PART
ajbspi-37615	24	10	synthesize	synthesize	VERB
ajbspi-37615	24	11	and	and	CCONJ
ajbspi-37615	24	12	evaluate	evaluate	VERB
ajbspi-37615	24	13	a	a	DET
ajbspi-37615	24	14	novel	novel	ADJ
ajbspi-37615	24	15	amide	amide	NOUN
ajbspi-37615	24	16	-	-	PUNCT
ajbspi-37615	24	17	based	base	VERB
ajbspi-37615	24	18	mutual	mutual	ADJ
ajbspi-37615	24	19	prodrug	prodrug	NOUN
ajbspi-37615	24	20	,	,	PUNCT
ajbspi-37615	24	21	designed	design	VERB
ajbspi-37615	24	22	to	to	PART
ajbspi-37615	24	23	improve	improve	VERB
ajbspi-37615	24	24	the	the	DET
ajbspi-37615	24	25	delivery	delivery	NOUN
ajbspi-37615	24	26	and	and	CCONJ
ajbspi-37615	24	27	pharmacological	pharmacological	ADJ
ajbspi-37615	24	28	properties	property	NOUN
ajbspi-37615	24	29	of	of	ADP
ajbspi-37615	24	30	the	the	DET
ajbspi-37615	24	31	parent	parent	NOUN
ajbspi-37615	24	32	drug	drug	NOUN
ajbspi-37615	24	33	.	.	PUNCT
ajbspi-37615	25	1	the	the	DET
ajbspi-37615	25	2	investigation	investigation	NOUN
ajbspi-37615	25	3	of	of	ADP
ajbspi-37615	25	4	this	this	DET
ajbspi-37615	25	5	prodrug	prodrug	NOUN
ajbspi-37615	25	6	's	's	PART
ajbspi-37615	25	7	synthesis	synthesis	NOUN
ajbspi-37615	25	8	and	and	CCONJ
ajbspi-37615	25	9	evaluation	evaluation	NOUN
ajbspi-37615	25	10	will	will	AUX
ajbspi-37615	25	11	provide	provide	VERB
ajbspi-37615	25	12	valuable	valuable	ADJ
ajbspi-37615	25	13	insights	insight	NOUN
ajbspi-37615	25	14	into	into	ADP
ajbspi-37615	25	15	its	its	PRON
ajbspi-37615	25	16	potential	potential	ADJ
ajbspi-37615	25	17	advantages	advantage	NOUN
ajbspi-37615	25	18	and	and	CCONJ
ajbspi-37615	25	19	limitations	limitation	NOUN
ajbspi-37615	25	20	,	,	PUNCT
ajbspi-37615	25	21	offering	offer	VERB
ajbspi-37615	25	22	a	a	DET
ajbspi-37615	25	23	foundation	foundation	NOUN
ajbspi-37615	25	24	for	for	ADP
ajbspi-37615	25	25	future	future	ADJ
ajbspi-37615	25	26	optimization	optimization	NOUN
ajbspi-37615	25	27	and	and	CCONJ
ajbspi-37615	25	28	development	development	NOUN
ajbspi-37615	25	29	of	of	ADP
ajbspi-37615	25	30	more	more	ADV
ajbspi-37615	25	31	efficient	efficient	ADJ
ajbspi-37615	25	32	drug	drug	NOUN
ajbspi-37615	25	33	delivery	delivery	NOUN
ajbspi-37615	25	34	systems	system	NOUN
ajbspi-37615	25	35	.	.	PUNCT
ajbspi-37615	26	1	in	in	ADP
ajbspi-37615	26	2	summary	summary	NOUN
ajbspi-37615	26	3	,	,	PUNCT
ajbspi-37615	26	4	the	the	DET
ajbspi-37615	26	5	study	study	NOUN
ajbspi-37615	26	6	of	of	ADP
ajbspi-37615	26	7	amide	amide	NOUN
ajbspi-37615	26	8	-	-	PUNCT
ajbspi-37615	26	9	based	base	VERB
ajbspi-37615	26	10	mutual	mutual	ADJ
ajbspi-37615	26	11	prodrugs	prodrug	NOUN
ajbspi-37615	26	12	represents	represent	VERB
ajbspi-37615	26	13	an	an	DET
ajbspi-37615	26	14	exciting	exciting	ADJ
ajbspi-37615	26	15	frontier	frontier	NOUN
ajbspi-37615	26	16	in	in	ADP
ajbspi-37615	26	17	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	PROPN
ajbspi-37615	26	18	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	NOUN
ajbspi-37615	26	19	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	ADJ
ajbspi-37615	26	20	volume	volume	NOUN
ajbspi-37615	26	21	03	03	NUM
ajbspi-37615	26	22	issue	issue	NOUN
ajbspi-37615	26	23	08	08	NUM
ajbspi-37615	26	24	-	-	SYM
ajbspi-37615	26	25	2023	2023	NUM
ajbspi-37615	26	26	12	12	NUM
ajbspi-37615	26	27	american	american	ADJ
ajbspi-37615	26	28	journal	journal	PROPN
ajbspi-37615	26	29	of	of	ADP
ajbspi-37615	26	30	biomedical	biomedical	PROPN
ajbspi-37615	26	31	science	science	PROPN
ajbspi-37615	26	32	&	&	CCONJ
ajbspi-37615	26	33	pharmaceutical	pharmaceutical	PROPN
ajbspi-37615	26	34	innovation	innovation	NOUN
ajbspi-37615	26	35	(	(	PUNCT
ajbspi-37615	26	36	issn	issn	PROPN
ajbspi-37615	26	37	–	–	PUNCT
ajbspi-37615	26	38	2771	2771	NUM
ajbspi-37615	26	39	-	-	SYM
ajbspi-37615	26	40	2753	2753	NUM
ajbspi-37615	26	41	)	)	PUNCT
ajbspi-37615	26	42	volume	volume	NOUN
ajbspi-37615	26	43	03	03	NUM
ajbspi-37615	26	44	issue	issue	NOUN
ajbspi-37615	26	45	08	08	NUM
ajbspi-37615	26	46	pages	page	NOUN
ajbspi-37615	26	47	:	:	PUNCT
ajbspi-37615	26	48	10	10	NUM
ajbspi-37615	26	49	-	-	SYM
ajbspi-37615	26	50	15	15	NUM
ajbspi-37615	26	51	sjif	sjif	NOUN
ajbspi-37615	26	52	impact	impact	NOUN
ajbspi-37615	26	53	factor	factor	NOUN
ajbspi-37615	26	54	(	(	PUNCT
ajbspi-37615	26	55	2021	2021	NUM
ajbspi-37615	26	56	:	:	PUNCT
ajbspi-37615	26	57	5	5	NUM
ajbspi-37615	26	58	.	.	NOUN
ajbspi-37615	26	59	705	705	NUM
ajbspi-37615	26	60	)	)	PUNCT
ajbspi-37615	26	61	(	(	PUNCT
ajbspi-37615	26	62	2022	2022	NUM
ajbspi-37615	26	63	:	:	PUNCT
ajbspi-37615	26	64	5	5	NUM
ajbspi-37615	26	65	.	.	NOUN
ajbspi-37615	26	66	705	705	NUM
ajbspi-37615	26	67	)	)	PUNCT
ajbspi-37615	26	68	(	(	PUNCT
ajbspi-37615	26	69	2023	2023	NUM
ajbspi-37615	26	70	:	:	PUNCT
ajbspi-37615	26	71	6.534	6.534	NUM
ajbspi-37615	26	72	)	)	PUNCT
ajbspi-37615	26	73	oclc	oclc	PROPN
ajbspi-37615	26	74	–	–	PUNCT
ajbspi-37615	26	75	1121105677	1121105677	NUM
ajbspi-37615	26	76	publisher	publisher	NOUN
ajbspi-37615	26	77	:	:	PUNCT
ajbspi-37615	26	78	oscar	oscar	NOUN
ajbspi-37615	26	79	publishing	publishing	NOUN
ajbspi-37615	26	80	services	service	NOUN
ajbspi-37615	26	81	servi	servi	PROPN
ajbspi-37615	26	82	pharmaceutical	pharmaceutical	PROPN
ajbspi-37615	26	83	research	research	NOUN
ajbspi-37615	26	84	,	,	PUNCT
ajbspi-37615	26	85	with	with	ADP
ajbspi-37615	26	86	the	the	DET
ajbspi-37615	26	87	potential	potential	NOUN
ajbspi-37615	26	88	to	to	PART
ajbspi-37615	26	89	revolutionize	revolutionize	VERB
ajbspi-37615	26	90	drug	drug	NOUN
ajbspi-37615	26	91	delivery	delivery	NOUN
ajbspi-37615	26	92	and	and	CCONJ
ajbspi-37615	26	93	therapeutic	therapeutic	ADJ
ajbspi-37615	26	94	outcomes	outcome	NOUN
ajbspi-37615	26	95	.	.	PUNCT
ajbspi-37615	27	1	the	the	DET
ajbspi-37615	27	2	outcomes	outcome	NOUN
ajbspi-37615	27	3	of	of	ADP
ajbspi-37615	27	4	this	this	DET
ajbspi-37615	27	5	research	research	NOUN
ajbspi-37615	27	6	could	could	AUX
ajbspi-37615	27	7	significantly	significantly	ADV
ajbspi-37615	27	8	contribute	contribute	VERB
ajbspi-37615	27	9	to	to	ADP
ajbspi-37615	27	10	advancing	advance	VERB
ajbspi-37615	27	11	the	the	DET
ajbspi-37615	27	12	field	field	NOUN
ajbspi-37615	27	13	of	of	ADP
ajbspi-37615	27	14	prodrug	prodrug	NOUN
ajbspi-37615	27	15	-	-	PUNCT
ajbspi-37615	27	16	based	base	VERB
ajbspi-37615	27	17	approaches	approach	NOUN
ajbspi-37615	27	18	,	,	PUNCT
ajbspi-37615	27	19	offering	offer	VERB
ajbspi-37615	27	20	novel	novel	ADJ
ajbspi-37615	27	21	solutions	solution	NOUN
ajbspi-37615	27	22	to	to	PART
ajbspi-37615	27	23	improve	improve	VERB
ajbspi-37615	27	24	the	the	DET
ajbspi-37615	27	25	performance	performance	NOUN
ajbspi-37615	27	26	of	of	ADP
ajbspi-37615	27	27	existing	exist	VERB
ajbspi-37615	27	28	drugs	drug	NOUN
ajbspi-37615	27	29	and	and	CCONJ
ajbspi-37615	27	30	enable	enable	VERB
ajbspi-37615	27	31	the	the	DET
ajbspi-37615	27	32	development	development	NOUN
ajbspi-37615	27	33	of	of	ADP
ajbspi-37615	27	34	innovative	innovative	ADJ
ajbspi-37615	27	35	therapeutics	therapeutic	NOUN
ajbspi-37615	27	36	for	for	ADP
ajbspi-37615	27	37	various	various	ADJ
ajbspi-37615	27	38	medical	medical	ADJ
ajbspi-37615	27	39	conditions	condition	NOUN
ajbspi-37615	27	40	.	.	PUNCT
ajbspi-37615	28	1	method	method	NOUN
ajbspi-37615	28	2	selection	selection	NOUN
ajbspi-37615	28	3	of	of	ADP
ajbspi-37615	28	4	parent	parent	NOUN
ajbspi-37615	28	5	drugs	drug	NOUN
ajbspi-37615	28	6	:	:	PUNCT
ajbspi-37615	28	7	identify	identify	VERB
ajbspi-37615	28	8	two	two	NUM
ajbspi-37615	28	9	suitable	suitable	ADJ
ajbspi-37615	28	10	parent	parent	NOUN
ajbspi-37615	28	11	drugs	drug	NOUN
ajbspi-37615	28	12	that	that	PRON
ajbspi-37615	28	13	exhibit	exhibit	VERB
ajbspi-37615	28	14	complementary	complementary	ADJ
ajbspi-37615	28	15	pharmacological	pharmacological	NOUN
ajbspi-37615	28	16	activities	activity	NOUN
ajbspi-37615	28	17	or	or	CCONJ
ajbspi-37615	28	18	possess	possess	VERB
ajbspi-37615	28	19	potential	potential	ADJ
ajbspi-37615	28	20	therapeutic	therapeutic	ADJ
ajbspi-37615	28	21	synergies	synergy	NOUN
ajbspi-37615	28	22	.	.	PUNCT
ajbspi-37615	29	1	consider	consider	VERB
ajbspi-37615	29	2	factors	factor	NOUN
ajbspi-37615	29	3	such	such	ADJ
ajbspi-37615	29	4	as	as	ADP
ajbspi-37615	29	5	chemical	chemical	ADJ
ajbspi-37615	29	6	compatibility	compatibility	NOUN
ajbspi-37615	29	7	,	,	PUNCT
ajbspi-37615	29	8	solubility	solubility	NOUN
ajbspi-37615	29	9	,	,	PUNCT
ajbspi-37615	29	10	stability	stability	NOUN
ajbspi-37615	29	11	,	,	PUNCT
ajbspi-37615	29	12	and	and	CCONJ
ajbspi-37615	29	13	known	know	VERB
ajbspi-37615	29	14	pharmacological	pharmacological	ADJ
ajbspi-37615	29	15	properties	property	NOUN
ajbspi-37615	29	16	.	.	PUNCT
ajbspi-37615	30	1	design	design	NOUN
ajbspi-37615	30	2	of	of	ADP
ajbspi-37615	30	3	the	the	DET
ajbspi-37615	30	4	amide	amide	NOUN
ajbspi-37615	30	5	-	-	PUNCT
ajbspi-37615	30	6	based	base	VERB
ajbspi-37615	30	7	mutual	mutual	ADJ
ajbspi-37615	30	8	prodrug	prodrug	NOUN
ajbspi-37615	30	9	:	:	PUNCT
ajbspi-37615	30	10	based	base	VERB
ajbspi-37615	30	11	on	on	ADP
ajbspi-37615	30	12	the	the	DET
ajbspi-37615	30	13	selected	select	VERB
ajbspi-37615	30	14	parent	parent	NOUN
ajbspi-37615	30	15	drugs	drug	NOUN
ajbspi-37615	30	16	,	,	PUNCT
ajbspi-37615	30	17	design	design	VERB
ajbspi-37615	30	18	a	a	DET
ajbspi-37615	30	19	suitable	suitable	ADJ
ajbspi-37615	30	20	amide	amide	NOUN
ajbspi-37615	30	21	-	-	PUNCT
ajbspi-37615	30	22	based	base	VERB
ajbspi-37615	30	23	mutual	mutual	ADJ
ajbspi-37615	30	24	prodrug	prodrug	NOUN
ajbspi-37615	30	25	by	by	ADP
ajbspi-37615	30	26	establishing	establish	VERB
ajbspi-37615	30	27	a	a	DET
ajbspi-37615	30	28	covalent	covalent	ADJ
ajbspi-37615	30	29	linkage	linkage	NOUN
ajbspi-37615	30	30	between	between	ADP
ajbspi-37615	30	31	them	they	PRON
ajbspi-37615	30	32	through	through	ADP
ajbspi-37615	30	33	an	an	DET
ajbspi-37615	30	34	amide	amide	NOUN
ajbspi-37615	30	35	bond	bond	NOUN
ajbspi-37615	30	36	.	.	PUNCT
ajbspi-37615	31	1	plan	plan	VERB
ajbspi-37615	31	2	the	the	DET
ajbspi-37615	31	3	synthesis	synthesis	NOUN
ajbspi-37615	31	4	strategy	strategy	NOUN
ajbspi-37615	31	5	to	to	PART
ajbspi-37615	31	6	ensure	ensure	VERB
ajbspi-37615	31	7	the	the	DET
ajbspi-37615	31	8	formation	formation	NOUN
ajbspi-37615	31	9	of	of	ADP
ajbspi-37615	31	10	a	a	DET
ajbspi-37615	31	11	stable	stable	ADJ
ajbspi-37615	31	12	and	and	CCONJ
ajbspi-37615	31	13	biocompatible	biocompatible	ADJ
ajbspi-37615	31	14	prodrug	prodrug	NOUN
ajbspi-37615	31	15	entity	entity	NOUN
ajbspi-37615	31	16	.	.	PUNCT
ajbspi-37615	32	1	synthesis	synthesis	NOUN
ajbspi-37615	32	2	of	of	ADP
ajbspi-37615	32	3	the	the	DET
ajbspi-37615	32	4	amide	amide	NOUN
ajbspi-37615	32	5	-	-	PUNCT
ajbspi-37615	32	6	based	base	VERB
ajbspi-37615	32	7	mutual	mutual	ADJ
ajbspi-37615	32	8	prodrug	prodrug	NOUN
ajbspi-37615	32	9	:	:	PUNCT
ajbspi-37615	32	10	perform	perform	VERB
ajbspi-37615	32	11	the	the	DET
ajbspi-37615	32	12	chemical	chemical	ADJ
ajbspi-37615	32	13	synthesis	synthesis	NOUN
ajbspi-37615	32	14	of	of	ADP
ajbspi-37615	32	15	the	the	DET
ajbspi-37615	32	16	amide	amide	NOUN
ajbspi-37615	32	17	-	-	PUNCT
ajbspi-37615	32	18	based	base	VERB
ajbspi-37615	32	19	mutual	mutual	ADJ
ajbspi-37615	32	20	prodrug	prodrug	NOUN
ajbspi-37615	32	21	following	follow	VERB
ajbspi-37615	32	22	standard	standard	ADJ
ajbspi-37615	32	23	laboratory	laboratory	NOUN
ajbspi-37615	32	24	techniques	technique	NOUN
ajbspi-37615	32	25	.	.	PUNCT
ajbspi-37615	33	1	utilize	utilize	VERB
ajbspi-37615	33	2	appropriate	appropriate	ADJ
ajbspi-37615	33	3	reagents	reagent	NOUN
ajbspi-37615	33	4	,	,	PUNCT
ajbspi-37615	33	5	solvents	solvent	NOUN
ajbspi-37615	33	6	,	,	PUNCT
ajbspi-37615	33	7	and	and	CCONJ
ajbspi-37615	33	8	protective	protective	ADJ
ajbspi-37615	33	9	groups	group	NOUN
ajbspi-37615	33	10	as	as	SCONJ
ajbspi-37615	33	11	required	require	VERB
ajbspi-37615	33	12	.	.	PUNCT
ajbspi-37615	34	1	monitor	monitor	VERB
ajbspi-37615	34	2	the	the	DET
ajbspi-37615	34	3	reaction	reaction	NOUN
ajbspi-37615	34	4	progress	progress	NOUN
ajbspi-37615	34	5	using	use	VERB
ajbspi-37615	34	6	analytical	analytical	ADJ
ajbspi-37615	34	7	techniques	technique	NOUN
ajbspi-37615	34	8	such	such	ADJ
ajbspi-37615	34	9	as	as	ADP
ajbspi-37615	34	10	thin	thin	ADJ
ajbspi-37615	34	11	-	-	PUNCT
ajbspi-37615	34	12	layer	layer	NOUN
ajbspi-37615	34	13	chromatography	chromatography	NOUN
ajbspi-37615	34	14	(	(	PUNCT
ajbspi-37615	34	15	tlc	tlc	NOUN
ajbspi-37615	34	16	)	)	PUNCT
ajbspi-37615	34	17	,	,	PUNCT
ajbspi-37615	34	18	high	high	ADJ
ajbspi-37615	34	19	-	-	PUNCT
ajbspi-37615	34	20	performance	performance	NOUN
ajbspi-37615	34	21	liquid	liquid	ADJ
ajbspi-37615	34	22	chromatography	chromatography	NOUN
ajbspi-37615	34	23	(	(	PUNCT
ajbspi-37615	34	24	hplc	hplc	PROPN
ajbspi-37615	34	25	)	)	PUNCT
ajbspi-37615	34	26	,	,	PUNCT
ajbspi-37615	34	27	or	or	CCONJ
ajbspi-37615	34	28	nuclear	nuclear	ADJ
ajbspi-37615	34	29	magnetic	magnetic	ADJ
ajbspi-37615	34	30	resonance	resonance	NOUN
ajbspi-37615	34	31	(	(	PUNCT
ajbspi-37615	34	32	nmr	nmr	NOUN
ajbspi-37615	34	33	)	)	PUNCT
ajbspi-37615	34	34	spectroscopy	spectroscopy	NOUN
ajbspi-37615	34	35	.	.	PUNCT
ajbspi-37615	35	1	purification	purification	NOUN
ajbspi-37615	35	2	and	and	CCONJ
ajbspi-37615	35	3	characterization	characterization	NOUN
ajbspi-37615	35	4	:	:	PUNCT
ajbspi-37615	35	5	purify	purify	VERB
ajbspi-37615	35	6	the	the	DET
ajbspi-37615	35	7	synthesized	synthesize	VERB
ajbspi-37615	35	8	prodrug	prodrug	NOUN
ajbspi-37615	35	9	to	to	PART
ajbspi-37615	35	10	obtain	obtain	VERB
ajbspi-37615	35	11	a	a	DET
ajbspi-37615	35	12	high	high	ADJ
ajbspi-37615	35	13	-	-	PUNCT
ajbspi-37615	35	14	quality	quality	NOUN
ajbspi-37615	35	15	product	product	NOUN
ajbspi-37615	35	16	with	with	ADP
ajbspi-37615	35	17	minimum	minimum	ADJ
ajbspi-37615	35	18	impurities	impurity	NOUN
ajbspi-37615	35	19	.	.	PUNCT
ajbspi-37615	36	1	techniques	technique	NOUN
ajbspi-37615	36	2	such	such	ADJ
ajbspi-37615	36	3	as	as	ADP
ajbspi-37615	36	4	recrystallization	recrystallization	NOUN
ajbspi-37615	36	5	,	,	PUNCT
ajbspi-37615	36	6	column	column	NOUN
ajbspi-37615	36	7	chromatography	chromatography	NOUN
ajbspi-37615	36	8	,	,	PUNCT
ajbspi-37615	36	9	or	or	CCONJ
ajbspi-37615	36	10	preparative	preparative	ADJ
ajbspi-37615	36	11	hplc	hplc	NOUN
ajbspi-37615	36	12	can	can	AUX
ajbspi-37615	36	13	be	be	AUX
ajbspi-37615	36	14	employed	employ	VERB
ajbspi-37615	36	15	for	for	ADP
ajbspi-37615	36	16	purification	purification	NOUN
ajbspi-37615	36	17	.	.	PUNCT
ajbspi-37615	37	1	characterize	characterize	VERB
ajbspi-37615	37	2	the	the	DET
ajbspi-37615	37	3	synthesized	synthesize	VERB
ajbspi-37615	37	4	prodrug	prodrug	NOUN
ajbspi-37615	37	5	using	use	VERB
ajbspi-37615	37	6	various	various	ADJ
ajbspi-37615	37	7	analytical	analytical	ADJ
ajbspi-37615	37	8	tools	tool	NOUN
ajbspi-37615	37	9	,	,	PUNCT
ajbspi-37615	37	10	including	include	VERB
ajbspi-37615	37	11	fourier	fourier	NOUN
ajbspi-37615	37	12	-	-	PUNCT
ajbspi-37615	37	13	transform	transform	NOUN
ajbspi-37615	37	14	infrared	infrared	ADJ
ajbspi-37615	37	15	spectroscopy	spectroscopy	NOUN
ajbspi-37615	37	16	(	(	PUNCT
ajbspi-37615	37	17	ft	ft	NOUN
ajbspi-37615	37	18	-	-	PUNCT
ajbspi-37615	37	19	ir	ir	NOUN
ajbspi-37615	37	20	)	)	PUNCT
ajbspi-37615	37	21	,	,	PUNCT
ajbspi-37615	37	22	mass	mass	ADJ
ajbspi-37615	37	23	spectrometry	spectrometry	NOUN
ajbspi-37615	37	24	,	,	PUNCT
ajbspi-37615	37	25	and	and	CCONJ
ajbspi-37615	37	26	nmr	nmr	NOUN
ajbspi-37615	37	27	,	,	PUNCT
ajbspi-37615	37	28	to	to	PART
ajbspi-37615	37	29	confirm	confirm	VERB
ajbspi-37615	37	30	its	its	PRON
ajbspi-37615	37	31	chemical	chemical	NOUN
ajbspi-37615	37	32	structure	structure	NOUN
ajbspi-37615	37	33	and	and	CCONJ
ajbspi-37615	37	34	identity	identity	NOUN
ajbspi-37615	37	35	.	.	PUNCT
ajbspi-37615	38	1	physicochemical	physicochemical	ADJ
ajbspi-37615	38	2	characterization	characterization	NOUN
ajbspi-37615	38	3	:	:	PUNCT
ajbspi-37615	38	4	evaluate	evaluate	VERB
ajbspi-37615	38	5	the	the	DET
ajbspi-37615	38	6	physicochemical	physicochemical	ADJ
ajbspi-37615	38	7	properties	property	NOUN
ajbspi-37615	38	8	of	of	ADP
ajbspi-37615	38	9	the	the	DET
ajbspi-37615	38	10	amidebased	amidebase	VERB
ajbspi-37615	38	11	mutual	mutual	ADJ
ajbspi-37615	38	12	prodrug	prodrug	NOUN
ajbspi-37615	38	13	,	,	PUNCT
ajbspi-37615	38	14	including	include	VERB
ajbspi-37615	38	15	solubility	solubility	NOUN
ajbspi-37615	38	16	,	,	PUNCT
ajbspi-37615	38	17	melting	melting	NOUN
ajbspi-37615	38	18	point	point	NOUN
ajbspi-37615	38	19	,	,	PUNCT
ajbspi-37615	38	20	and	and	CCONJ
ajbspi-37615	38	21	partition	partition	NOUN
ajbspi-37615	38	22	coefficient	coefficient	NOUN
ajbspi-37615	38	23	.	.	PUNCT
ajbspi-37615	39	1	these	these	DET
ajbspi-37615	39	2	properties	property	NOUN
ajbspi-37615	39	3	influence	influence	VERB
ajbspi-37615	39	4	the	the	DET
ajbspi-37615	39	5	prodrug	prodrug	NOUN
ajbspi-37615	39	6	's	's	PART
ajbspi-37615	39	7	potential	potential	NOUN
ajbspi-37615	39	8	for	for	ADP
ajbspi-37615	39	9	drug	drug	NOUN
ajbspi-37615	39	10	delivery	delivery	NOUN
ajbspi-37615	39	11	and	and	CCONJ
ajbspi-37615	39	12	its	its	PRON
ajbspi-37615	39	13	compatibility	compatibility	NOUN
ajbspi-37615	39	14	with	with	ADP
ajbspi-37615	39	15	various	various	ADJ
ajbspi-37615	39	16	pharmaceutical	pharmaceutical	ADJ
ajbspi-37615	39	17	formulations	formulation	NOUN
ajbspi-37615	39	18	.	.	PUNCT
ajbspi-37615	40	1	in	in	ADP
ajbspi-37615	40	2	vitro	vitro	X
ajbspi-37615	40	3	release	release	NOUN
ajbspi-37615	40	4	kinetics	kinetic	NOUN
ajbspi-37615	40	5	:	:	PUNCT
ajbspi-37615	40	6	assess	assess	VERB
ajbspi-37615	40	7	the	the	DET
ajbspi-37615	40	8	release	release	NOUN
ajbspi-37615	40	9	kinetics	kinetic	NOUN
ajbspi-37615	40	10	of	of	ADP
ajbspi-37615	40	11	the	the	DET
ajbspi-37615	40	12	active	active	ADJ
ajbspi-37615	40	13	moieties	moiety	NOUN
ajbspi-37615	40	14	from	from	ADP
ajbspi-37615	40	15	the	the	DET
ajbspi-37615	40	16	prodrug	prodrug	NOUN
ajbspi-37615	40	17	under	under	ADP
ajbspi-37615	40	18	simulated	simulated	ADJ
ajbspi-37615	40	19	physiological	physiological	ADJ
ajbspi-37615	40	20	conditions	condition	NOUN
ajbspi-37615	40	21	.	.	PUNCT
ajbspi-37615	41	1	conduct	conduct	VERB
ajbspi-37615	41	2	dissolution	dissolution	NOUN
ajbspi-37615	41	3	studies	study	NOUN
ajbspi-37615	41	4	using	use	VERB
ajbspi-37615	41	5	appropriate	appropriate	ADJ
ajbspi-37615	41	6	media	medium	NOUN
ajbspi-37615	41	7	and	and	CCONJ
ajbspi-37615	41	8	measure	measure	VERB
ajbspi-37615	41	9	the	the	DET
ajbspi-37615	41	10	release	release	NOUN
ajbspi-37615	41	11	of	of	ADP
ajbspi-37615	41	12	parent	parent	NOUN
ajbspi-37615	41	13	drugs	drug	NOUN
ajbspi-37615	41	14	over	over	ADP
ajbspi-37615	41	15	time	time	NOUN
ajbspi-37615	41	16	.	.	PUNCT
ajbspi-37615	42	1	analyze	analyze	VERB
ajbspi-37615	42	2	the	the	DET
ajbspi-37615	42	3	release	release	NOUN
ajbspi-37615	42	4	profiles	profile	NOUN
ajbspi-37615	42	5	to	to	PART
ajbspi-37615	42	6	understand	understand	VERB
ajbspi-37615	42	7	the	the	DET
ajbspi-37615	42	8	drug	drug	NOUN
ajbspi-37615	42	9	release	release	NOUN
ajbspi-37615	42	10	mechanism	mechanism	NOUN
ajbspi-37615	42	11	and	and	CCONJ
ajbspi-37615	42	12	kinetics	kinetic	NOUN
ajbspi-37615	42	13	.	.	PUNCT
ajbspi-37615	43	1	enzymatic	enzymatic	ADJ
ajbspi-37615	43	2	hydrolysis	hydrolysis	NOUN
ajbspi-37615	43	3	studies	study	NOUN
ajbspi-37615	43	4	:	:	PUNCT
ajbspi-37615	43	5	investigate	investigate	VERB
ajbspi-37615	43	6	the	the	DET
ajbspi-37615	43	7	susceptibility	susceptibility	NOUN
ajbspi-37615	43	8	of	of	ADP
ajbspi-37615	43	9	the	the	DET
ajbspi-37615	43	10	amide	amide	NOUN
ajbspi-37615	43	11	bond	bond	NOUN
ajbspi-37615	43	12	in	in	ADP
ajbspi-37615	43	13	the	the	DET
ajbspi-37615	43	14	mutual	mutual	ADJ
ajbspi-37615	43	15	prodrug	prodrug	NOUN
ajbspi-37615	43	16	to	to	PART
ajbspi-37615	43	17	enzymatic	enzymatic	VERB
ajbspi-37615	43	18	hydrolysis	hydrolysis	NOUN
ajbspi-37615	43	19	using	use	VERB
ajbspi-37615	43	20	relevant	relevant	ADJ
ajbspi-37615	43	21	enzymes	enzyme	NOUN
ajbspi-37615	43	22	,	,	PUNCT
ajbspi-37615	43	23	such	such	ADJ
ajbspi-37615	43	24	as	as	ADP
ajbspi-37615	43	25	esterases	esterase	NOUN
ajbspi-37615	43	26	or	or	CCONJ
ajbspi-37615	43	27	proteases	protease	NOUN
ajbspi-37615	43	28	.	.	PUNCT
ajbspi-37615	44	1	monitor	monitor	VERB
ajbspi-37615	44	2	the	the	DET
ajbspi-37615	44	3	hydrolysis	hydrolysis	NOUN
ajbspi-37615	44	4	process	process	NOUN
ajbspi-37615	44	5	and	and	CCONJ
ajbspi-37615	44	6	quantify	quantify	VERB
ajbspi-37615	44	7	the	the	DET
ajbspi-37615	44	8	release	release	NOUN
ajbspi-37615	44	9	of	of	ADP
ajbspi-37615	44	10	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	NOUN
ajbspi-37615	44	11	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	NOUN
ajbspi-37615	44	12	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	ADJ
ajbspi-37615	44	13	volume	volume	NOUN
ajbspi-37615	44	14	03	03	NUM
ajbspi-37615	44	15	issue	issue	NOUN
ajbspi-37615	44	16	08	08	NUM
ajbspi-37615	44	17	-	-	SYM
ajbspi-37615	44	18	2023	2023	NUM
ajbspi-37615	44	19	13	13	NUM
ajbspi-37615	44	20	american	american	ADJ
ajbspi-37615	44	21	journal	journal	PROPN
ajbspi-37615	44	22	of	of	ADP
ajbspi-37615	44	23	biomedical	biomedical	PROPN
ajbspi-37615	44	24	science	science	PROPN
ajbspi-37615	44	25	&	&	CCONJ
ajbspi-37615	44	26	pharmaceutical	pharmaceutical	PROPN
ajbspi-37615	44	27	innovation	innovation	NOUN
ajbspi-37615	44	28	(	(	PUNCT
ajbspi-37615	44	29	issn	issn	PROPN
ajbspi-37615	44	30	–	–	PUNCT
ajbspi-37615	44	31	2771	2771	NUM
ajbspi-37615	44	32	-	-	SYM
ajbspi-37615	44	33	2753	2753	NUM
ajbspi-37615	44	34	)	)	PUNCT
ajbspi-37615	45	1	volume	volume	NOUN
ajbspi-37615	45	2	03	03	NUM
ajbspi-37615	45	3	issue	issue	NOUN
ajbspi-37615	45	4	08	08	NUM
ajbspi-37615	45	5	pages	page	NOUN
ajbspi-37615	45	6	:	:	PUNCT
ajbspi-37615	45	7	10	10	NUM
ajbspi-37615	45	8	-	-	SYM
ajbspi-37615	45	9	15	15	NUM
ajbspi-37615	45	10	sjif	sjif	NOUN
ajbspi-37615	45	11	impact	impact	NOUN
ajbspi-37615	45	12	factor	factor	NOUN
ajbspi-37615	45	13	(	(	PUNCT
ajbspi-37615	45	14	2021	2021	NUM
ajbspi-37615	45	15	:	:	PUNCT
ajbspi-37615	45	16	5	5	NUM
ajbspi-37615	45	17	.	.	NOUN
ajbspi-37615	45	18	705	705	NUM
ajbspi-37615	45	19	)	)	PUNCT
ajbspi-37615	45	20	(	(	PUNCT
ajbspi-37615	45	21	2022	2022	NUM
ajbspi-37615	45	22	:	:	PUNCT
ajbspi-37615	45	23	5	5	NUM
ajbspi-37615	45	24	.	.	NOUN
ajbspi-37615	45	25	705	705	NUM
ajbspi-37615	45	26	)	)	PUNCT
ajbspi-37615	45	27	(	(	PUNCT
ajbspi-37615	45	28	2023	2023	NUM
ajbspi-37615	45	29	:	:	PUNCT
ajbspi-37615	45	30	6.534	6.534	NUM
ajbspi-37615	45	31	)	)	PUNCT
ajbspi-37615	45	32	oclc	oclc	PROPN
ajbspi-37615	45	33	–	–	PUNCT
ajbspi-37615	45	34	1121105677	1121105677	NUM
ajbspi-37615	45	35	publisher	publisher	NOUN
ajbspi-37615	45	36	:	:	PUNCT
ajbspi-37615	45	37	oscar	oscar	NOUN
ajbspi-37615	45	38	publishing	publishing	NOUN
ajbspi-37615	45	39	services	service	NOUN
ajbspi-37615	45	40	servi	servi	ADJ
ajbspi-37615	45	41	individual	individual	ADJ
ajbspi-37615	45	42	parent	parent	NOUN
ajbspi-37615	45	43	drugs	drug	NOUN
ajbspi-37615	45	44	using	use	VERB
ajbspi-37615	45	45	analytical	analytical	ADJ
ajbspi-37615	45	46	methods	method	NOUN
ajbspi-37615	45	47	like	like	ADP
ajbspi-37615	45	48	hplc	hplc	NOUN
ajbspi-37615	45	49	or	or	CCONJ
ajbspi-37615	45	50	uv	uv	NOUN
ajbspi-37615	45	51	-	-	PUNCT
ajbspi-37615	45	52	vis	vis	X
ajbspi-37615	45	53	spectroscopy	spectroscopy	NOUN
ajbspi-37615	45	54	.	.	PUNCT
ajbspi-37615	46	1	pharmacological	pharmacological	ADJ
ajbspi-37615	46	2	evaluation	evaluation	NOUN
ajbspi-37615	46	3	:	:	PUNCT
ajbspi-37615	46	4	conduct	conduct	VERB
ajbspi-37615	46	5	pharmacological	pharmacological	ADJ
ajbspi-37615	46	6	evaluations	evaluation	NOUN
ajbspi-37615	46	7	of	of	ADP
ajbspi-37615	46	8	the	the	DET
ajbspi-37615	46	9	amidebased	amidebase	VERB
ajbspi-37615	46	10	mutual	mutual	ADJ
ajbspi-37615	46	11	prodrug	prodrug	NOUN
ajbspi-37615	46	12	and	and	CCONJ
ajbspi-37615	46	13	its	its	PRON
ajbspi-37615	46	14	parent	parent	NOUN
ajbspi-37615	46	15	drugs	drug	NOUN
ajbspi-37615	46	16	using	use	VERB
ajbspi-37615	46	17	suitable	suitable	ADJ
ajbspi-37615	46	18	in	in	ADP
ajbspi-37615	46	19	vitro	vitro	X
ajbspi-37615	46	20	or	or	CCONJ
ajbspi-37615	46	21	in	in	ADP
ajbspi-37615	46	22	vivo	vivo	NOUN
ajbspi-37615	46	23	models	model	NOUN
ajbspi-37615	46	24	.	.	PUNCT
ajbspi-37615	47	1	compare	compare	VERB
ajbspi-37615	47	2	the	the	DET
ajbspi-37615	47	3	pharmacological	pharmacological	ADJ
ajbspi-37615	47	4	activities	activity	NOUN
ajbspi-37615	47	5	,	,	PUNCT
ajbspi-37615	47	6	efficacy	efficacy	NOUN
ajbspi-37615	47	7	,	,	PUNCT
ajbspi-37615	47	8	and	and	CCONJ
ajbspi-37615	47	9	toxicity	toxicity	NOUN
ajbspi-37615	47	10	profiles	profile	NOUN
ajbspi-37615	47	11	of	of	ADP
ajbspi-37615	47	12	the	the	DET
ajbspi-37615	47	13	prodrug	prodrug	NOUN
ajbspi-37615	47	14	and	and	CCONJ
ajbspi-37615	47	15	individual	individual	ADJ
ajbspi-37615	47	16	parent	parent	NOUN
ajbspi-37615	47	17	drugs	drug	NOUN
ajbspi-37615	47	18	to	to	PART
ajbspi-37615	47	19	assess	assess	VERB
ajbspi-37615	47	20	any	any	DET
ajbspi-37615	47	21	potential	potential	ADJ
ajbspi-37615	47	22	enhancements	enhancement	NOUN
ajbspi-37615	47	23	in	in	ADP
ajbspi-37615	47	24	therapeutic	therapeutic	ADJ
ajbspi-37615	47	25	outcomes	outcome	NOUN
ajbspi-37615	47	26	.	.	PUNCT
ajbspi-37615	48	1	stability	stability	NOUN
ajbspi-37615	48	2	studies	study	NOUN
ajbspi-37615	48	3	:	:	PUNCT
ajbspi-37615	48	4	evaluate	evaluate	VERB
ajbspi-37615	48	5	the	the	DET
ajbspi-37615	48	6	stability	stability	NOUN
ajbspi-37615	48	7	of	of	ADP
ajbspi-37615	48	8	the	the	DET
ajbspi-37615	48	9	amide	amide	NOUN
ajbspi-37615	48	10	-	-	PUNCT
ajbspi-37615	48	11	based	base	VERB
ajbspi-37615	48	12	mutual	mutual	ADJ
ajbspi-37615	48	13	prodrug	prodrug	NOUN
ajbspi-37615	48	14	under	under	ADP
ajbspi-37615	48	15	various	various	ADJ
ajbspi-37615	48	16	storage	storage	NOUN
ajbspi-37615	48	17	conditions	condition	NOUN
ajbspi-37615	48	18	,	,	PUNCT
ajbspi-37615	48	19	including	include	VERB
ajbspi-37615	48	20	temperature	temperature	NOUN
ajbspi-37615	48	21	,	,	PUNCT
ajbspi-37615	48	22	humidity	humidity	NOUN
ajbspi-37615	48	23	,	,	PUNCT
ajbspi-37615	48	24	and	and	CCONJ
ajbspi-37615	48	25	light	light	ADJ
ajbspi-37615	48	26	exposure	exposure	NOUN
ajbspi-37615	48	27	.	.	PUNCT
ajbspi-37615	49	1	monitor	monitor	VERB
ajbspi-37615	49	2	any	any	DET
ajbspi-37615	49	3	changes	change	NOUN
ajbspi-37615	49	4	in	in	ADP
ajbspi-37615	49	5	chemical	chemical	ADJ
ajbspi-37615	49	6	structure	structure	NOUN
ajbspi-37615	49	7	,	,	PUNCT
ajbspi-37615	49	8	drug	drug	NOUN
ajbspi-37615	49	9	release	release	NOUN
ajbspi-37615	49	10	kinetics	kinetic	NOUN
ajbspi-37615	49	11	,	,	PUNCT
ajbspi-37615	49	12	or	or	CCONJ
ajbspi-37615	49	13	pharmacological	pharmacological	ADJ
ajbspi-37615	49	14	activity	activity	NOUN
ajbspi-37615	49	15	over	over	ADP
ajbspi-37615	49	16	time	time	NOUN
ajbspi-37615	49	17	.	.	PUNCT
ajbspi-37615	50	1	data	datum	NOUN
ajbspi-37615	50	2	analysis	analysis	NOUN
ajbspi-37615	50	3	:	:	PUNCT
ajbspi-37615	50	4	analyze	analyze	VERB
ajbspi-37615	50	5	the	the	DET
ajbspi-37615	50	6	experimental	experimental	ADJ
ajbspi-37615	50	7	data	datum	NOUN
ajbspi-37615	50	8	using	use	VERB
ajbspi-37615	50	9	appropriate	appropriate	ADJ
ajbspi-37615	50	10	statistical	statistical	ADJ
ajbspi-37615	50	11	methods	method	NOUN
ajbspi-37615	50	12	.	.	PUNCT
ajbspi-37615	51	1	draw	draw	VERB
ajbspi-37615	51	2	conclusions	conclusion	NOUN
ajbspi-37615	51	3	based	base	VERB
ajbspi-37615	51	4	on	on	ADP
ajbspi-37615	51	5	the	the	DET
ajbspi-37615	51	6	results	result	NOUN
ajbspi-37615	51	7	obtained	obtain	VERB
ajbspi-37615	51	8	from	from	ADP
ajbspi-37615	51	9	the	the	DET
ajbspi-37615	51	10	synthesis	synthesis	NOUN
ajbspi-37615	51	11	and	and	CCONJ
ajbspi-37615	51	12	evaluation	evaluation	NOUN
ajbspi-37615	51	13	of	of	ADP
ajbspi-37615	51	14	the	the	DET
ajbspi-37615	51	15	amide	amide	NOUN
ajbspi-37615	51	16	-	-	PUNCT
ajbspi-37615	51	17	based	base	VERB
ajbspi-37615	51	18	mutual	mutual	ADJ
ajbspi-37615	51	19	prodrug	prodrug	NOUN
ajbspi-37615	51	20	.	.	PUNCT
ajbspi-37615	52	1	the	the	DET
ajbspi-37615	52	2	synthesis	synthesis	NOUN
ajbspi-37615	52	3	and	and	CCONJ
ajbspi-37615	52	4	evaluation	evaluation	NOUN
ajbspi-37615	52	5	of	of	ADP
ajbspi-37615	52	6	the	the	DET
ajbspi-37615	52	7	amide	amide	NOUN
ajbspi-37615	52	8	-	-	PUNCT
ajbspi-37615	52	9	based	base	VERB
ajbspi-37615	52	10	mutual	mutual	ADJ
ajbspi-37615	52	11	prodrug	prodrug	NOUN
ajbspi-37615	52	12	require	require	VERB
ajbspi-37615	52	13	careful	careful	ADJ
ajbspi-37615	52	14	planning	planning	NOUN
ajbspi-37615	52	15	,	,	PUNCT
ajbspi-37615	52	16	rigorous	rigorous	ADJ
ajbspi-37615	52	17	experimentation	experimentation	NOUN
ajbspi-37615	52	18	,	,	PUNCT
ajbspi-37615	52	19	and	and	CCONJ
ajbspi-37615	52	20	systematic	systematic	ADJ
ajbspi-37615	52	21	data	datum	NOUN
ajbspi-37615	52	22	analysis	analysis	NOUN
ajbspi-37615	52	23	.	.	PUNCT
ajbspi-37615	53	1	successful	successful	ADJ
ajbspi-37615	53	2	execution	execution	NOUN
ajbspi-37615	53	3	of	of	ADP
ajbspi-37615	53	4	these	these	DET
ajbspi-37615	53	5	methods	method	NOUN
ajbspi-37615	53	6	will	will	AUX
ajbspi-37615	53	7	provide	provide	VERB
ajbspi-37615	53	8	valuable	valuable	ADJ
ajbspi-37615	53	9	insights	insight	NOUN
ajbspi-37615	53	10	into	into	ADP
ajbspi-37615	53	11	the	the	DET
ajbspi-37615	53	12	potential	potential	NOUN
ajbspi-37615	53	13	of	of	ADP
ajbspi-37615	53	14	the	the	DET
ajbspi-37615	53	15	prodrug	prodrug	NOUN
ajbspi-37615	53	16	for	for	ADP
ajbspi-37615	53	17	enhanced	enhanced	ADJ
ajbspi-37615	53	18	drug	drug	NOUN
ajbspi-37615	53	19	delivery	delivery	NOUN
ajbspi-37615	53	20	and	and	CCONJ
ajbspi-37615	53	21	improved	improve	VERB
ajbspi-37615	53	22	therapeutic	therapeutic	ADJ
ajbspi-37615	53	23	efficacy	efficacy	NOUN
ajbspi-37615	53	24	.	.	PUNCT
ajbspi-37615	54	1	results	result	VERB
ajbspi-37615	54	2	synthesis	synthesis	NOUN
ajbspi-37615	54	3	of	of	ADP
ajbspi-37615	54	4	amide	amide	NOUN
ajbspi-37615	54	5	-	-	PUNCT
ajbspi-37615	54	6	based	base	VERB
ajbspi-37615	54	7	mutual	mutual	ADJ
ajbspi-37615	54	8	prodrug	prodrug	NOUN
ajbspi-37615	54	9	:	:	PUNCT
ajbspi-37615	54	10	the	the	DET
ajbspi-37615	54	11	amide	amide	NOUN
ajbspi-37615	54	12	-	-	PUNCT
ajbspi-37615	54	13	based	base	VERB
ajbspi-37615	54	14	mutual	mutual	ADJ
ajbspi-37615	54	15	prodrug	prodrug	NOUN
ajbspi-37615	54	16	was	be	AUX
ajbspi-37615	54	17	successfully	successfully	ADV
ajbspi-37615	54	18	synthesized	synthesize	VERB
ajbspi-37615	54	19	using	use	VERB
ajbspi-37615	54	20	a	a	DET
ajbspi-37615	54	21	chemical	chemical	ADJ
ajbspi-37615	54	22	conjugation	conjugation	NOUN
ajbspi-37615	54	23	strategy	strategy	NOUN
ajbspi-37615	54	24	.	.	PUNCT
ajbspi-37615	55	1	the	the	DET
ajbspi-37615	55	2	reaction	reaction	NOUN
ajbspi-37615	55	3	progress	progress	NOUN
ajbspi-37615	55	4	was	be	AUX
ajbspi-37615	55	5	monitored	monitor	VERB
ajbspi-37615	55	6	using	use	VERB
ajbspi-37615	55	7	tlc	tlc	NOUN
ajbspi-37615	55	8	,	,	PUNCT
ajbspi-37615	55	9	and	and	CCONJ
ajbspi-37615	55	10	the	the	DET
ajbspi-37615	55	11	purity	purity	NOUN
ajbspi-37615	55	12	of	of	ADP
ajbspi-37615	55	13	the	the	DET
ajbspi-37615	55	14	final	final	ADJ
ajbspi-37615	55	15	product	product	NOUN
ajbspi-37615	55	16	was	be	AUX
ajbspi-37615	55	17	confirmed	confirm	VERB
ajbspi-37615	55	18	through	through	ADP
ajbspi-37615	55	19	hplc	hplc	NOUN
ajbspi-37615	55	20	and	and	CCONJ
ajbspi-37615	55	21	nmr	nmr	NOUN
ajbspi-37615	55	22	analysis	analysis	NOUN
ajbspi-37615	55	23	.	.	PUNCT
ajbspi-37615	56	1	physicochemical	physicochemical	ADJ
ajbspi-37615	56	2	characterization	characterization	NOUN
ajbspi-37615	56	3	:	:	PUNCT
ajbspi-37615	56	4	the	the	DET
ajbspi-37615	56	5	prodrug	prodrug	NOUN
ajbspi-37615	56	6	exhibited	exhibit	VERB
ajbspi-37615	56	7	improved	improve	VERB
ajbspi-37615	56	8	solubility	solubility	NOUN
ajbspi-37615	56	9	compared	compare	VERB
ajbspi-37615	56	10	to	to	ADP
ajbspi-37615	56	11	the	the	DET
ajbspi-37615	56	12	parent	parent	NOUN
ajbspi-37615	56	13	drugs	drug	NOUN
ajbspi-37615	56	14	,	,	PUNCT
ajbspi-37615	56	15	indicating	indicate	VERB
ajbspi-37615	56	16	its	its	PRON
ajbspi-37615	56	17	potential	potential	NOUN
ajbspi-37615	56	18	for	for	ADP
ajbspi-37615	56	19	enhanced	enhanced	ADJ
ajbspi-37615	56	20	drug	drug	NOUN
ajbspi-37615	56	21	delivery	delivery	NOUN
ajbspi-37615	56	22	.	.	PUNCT
ajbspi-37615	57	1	melting	melting	NOUN
ajbspi-37615	57	2	point	point	NOUN
ajbspi-37615	57	3	determination	determination	NOUN
ajbspi-37615	57	4	and	and	CCONJ
ajbspi-37615	57	5	partition	partition	NOUN
ajbspi-37615	57	6	coefficient	coefficient	NOUN
ajbspi-37615	57	7	analysis	analysis	NOUN
ajbspi-37615	57	8	further	far	ADV
ajbspi-37615	57	9	supported	support	VERB
ajbspi-37615	57	10	the	the	DET
ajbspi-37615	57	11	stability	stability	NOUN
ajbspi-37615	57	12	and	and	CCONJ
ajbspi-37615	57	13	compatibility	compatibility	NOUN
ajbspi-37615	57	14	of	of	ADP
ajbspi-37615	57	15	the	the	DET
ajbspi-37615	57	16	prodrug	prodrug	NOUN
ajbspi-37615	57	17	with	with	ADP
ajbspi-37615	57	18	various	various	ADJ
ajbspi-37615	57	19	pharmaceutical	pharmaceutical	ADJ
ajbspi-37615	57	20	formulations	formulation	NOUN
ajbspi-37615	57	21	.	.	PUNCT
ajbspi-37615	58	1	in	in	ADP
ajbspi-37615	58	2	vitro	vitro	X
ajbspi-37615	58	3	release	release	NOUN
ajbspi-37615	58	4	kinetics	kinetic	NOUN
ajbspi-37615	58	5	:	:	PUNCT
ajbspi-37615	58	6	dissolution	dissolution	PROPN
ajbspi-37615	58	7	studies	study	NOUN
ajbspi-37615	58	8	demonstrated	demonstrate	VERB
ajbspi-37615	58	9	controlled	control	VERB
ajbspi-37615	58	10	and	and	CCONJ
ajbspi-37615	58	11	sustained	sustained	ADJ
ajbspi-37615	58	12	release	release	NOUN
ajbspi-37615	58	13	of	of	ADP
ajbspi-37615	58	14	the	the	DET
ajbspi-37615	58	15	parent	parent	NOUN
ajbspi-37615	58	16	drugs	drug	NOUN
ajbspi-37615	58	17	from	from	ADP
ajbspi-37615	58	18	the	the	DET
ajbspi-37615	58	19	amidebased	amidebase	VERB
ajbspi-37615	58	20	mutual	mutual	ADJ
ajbspi-37615	58	21	prodrug	prodrug	NOUN
ajbspi-37615	58	22	.	.	PUNCT
ajbspi-37615	59	1	the	the	DET
ajbspi-37615	59	2	release	release	NOUN
ajbspi-37615	59	3	profiles	profile	NOUN
ajbspi-37615	59	4	indicated	indicate	VERB
ajbspi-37615	59	5	that	that	SCONJ
ajbspi-37615	59	6	the	the	DET
ajbspi-37615	59	7	prodrug	prodrug	NOUN
ajbspi-37615	59	8	maintained	maintain	VERB
ajbspi-37615	59	9	a	a	DET
ajbspi-37615	59	10	steady	steady	ADJ
ajbspi-37615	59	11	release	release	NOUN
ajbspi-37615	59	12	of	of	ADP
ajbspi-37615	59	13	active	active	ADJ
ajbspi-37615	59	14	moieties	moiety	NOUN
ajbspi-37615	59	15	,	,	PUNCT
ajbspi-37615	59	16	suggesting	suggest	VERB
ajbspi-37615	59	17	its	its	PRON
ajbspi-37615	59	18	potential	potential	NOUN
ajbspi-37615	59	19	for	for	ADP
ajbspi-37615	59	20	controlled	control	VERB
ajbspi-37615	59	21	drug	drug	NOUN
ajbspi-37615	59	22	delivery	delivery	NOUN
ajbspi-37615	59	23	.	.	PUNCT
ajbspi-37615	60	1	enzymatic	enzymatic	ADJ
ajbspi-37615	60	2	hydrolysis	hydrolysis	NOUN
ajbspi-37615	60	3	studies	study	NOUN
ajbspi-37615	60	4	:	:	PUNCT
ajbspi-37615	60	5	enzymatic	enzymatic	ADJ
ajbspi-37615	60	6	hydrolysis	hydrolysis	NOUN
ajbspi-37615	60	7	experiments	experiment	NOUN
ajbspi-37615	60	8	showed	show	VERB
ajbspi-37615	60	9	that	that	SCONJ
ajbspi-37615	60	10	the	the	DET
ajbspi-37615	60	11	amide	amide	NOUN
ajbspi-37615	60	12	bond	bond	NOUN
ajbspi-37615	60	13	in	in	ADP
ajbspi-37615	60	14	the	the	DET
ajbspi-37615	60	15	mutual	mutual	ADJ
ajbspi-37615	60	16	prodrug	prodrug	NOUN
ajbspi-37615	60	17	was	be	AUX
ajbspi-37615	60	18	susceptible	susceptible	ADJ
ajbspi-37615	60	19	to	to	ADP
ajbspi-37615	60	20	enzymatic	enzymatic	ADJ
ajbspi-37615	60	21	cleavage	cleavage	NOUN
ajbspi-37615	60	22	,	,	PUNCT
ajbspi-37615	60	23	leading	lead	VERB
ajbspi-37615	60	24	to	to	ADP
ajbspi-37615	60	25	the	the	DET
ajbspi-37615	60	26	liberation	liberation	NOUN
ajbspi-37615	60	27	of	of	ADP
ajbspi-37615	60	28	individual	individual	ADJ
ajbspi-37615	60	29	parent	parent	NOUN
ajbspi-37615	60	30	drugs	drug	NOUN
ajbspi-37615	60	31	.	.	PUNCT
ajbspi-37615	61	1	this	this	DET
ajbspi-37615	61	2	enzymatic	enzymatic	ADJ
ajbspi-37615	61	3	behavior	behavior	NOUN
ajbspi-37615	61	4	confirmed	confirm	VERB
ajbspi-37615	61	5	the	the	DET
ajbspi-37615	61	6	biodegradability	biodegradability	NOUN
ajbspi-37615	61	7	of	of	ADP
ajbspi-37615	61	8	the	the	DET
ajbspi-37615	61	9	prodrug	prodrug	NOUN
ajbspi-37615	61	10	,	,	PUNCT
ajbspi-37615	61	11	supporting	support	VERB
ajbspi-37615	61	12	its	its	PRON
ajbspi-37615	61	13	ability	ability	NOUN
ajbspi-37615	61	14	to	to	PART
ajbspi-37615	61	15	release	release	VERB
ajbspi-37615	61	16	active	active	ADJ
ajbspi-37615	61	17	moieties	moiety	NOUN
ajbspi-37615	61	18	in	in	ADP
ajbspi-37615	61	19	a	a	DET
ajbspi-37615	61	20	controlled	control	VERB
ajbspi-37615	61	21	manner	manner	NOUN
ajbspi-37615	61	22	.	.	PUNCT
ajbspi-37615	62	1	pharmacological	pharmacological	ADJ
ajbspi-37615	62	2	evaluation	evaluation	NOUN
ajbspi-37615	62	3	:	:	PUNCT
ajbspi-37615	63	1	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	ADJ
ajbspi-37615	63	2	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	NOUN
ajbspi-37615	63	3	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	ADJ
ajbspi-37615	63	4	volume	volume	NOUN
ajbspi-37615	63	5	03	03	NUM
ajbspi-37615	63	6	issue	issue	NOUN
ajbspi-37615	63	7	08	08	NUM
ajbspi-37615	63	8	-	-	SYM
ajbspi-37615	63	9	2023	2023	NUM
ajbspi-37615	63	10	14	14	NUM
ajbspi-37615	63	11	american	american	ADJ
ajbspi-37615	63	12	journal	journal	PROPN
ajbspi-37615	63	13	of	of	ADP
ajbspi-37615	63	14	biomedical	biomedical	PROPN
ajbspi-37615	63	15	science	science	PROPN
ajbspi-37615	63	16	&	&	CCONJ
ajbspi-37615	63	17	pharmaceutical	pharmaceutical	PROPN
ajbspi-37615	63	18	innovation	innovation	NOUN
ajbspi-37615	63	19	(	(	PUNCT
ajbspi-37615	63	20	issn	issn	PROPN
ajbspi-37615	63	21	–	–	PUNCT
ajbspi-37615	63	22	2771	2771	NUM
ajbspi-37615	63	23	-	-	SYM
ajbspi-37615	63	24	2753	2753	NUM
ajbspi-37615	63	25	)	)	PUNCT
ajbspi-37615	63	26	volume	volume	NOUN
ajbspi-37615	63	27	03	03	NUM
ajbspi-37615	63	28	issue	issue	NOUN
ajbspi-37615	63	29	08	08	NUM
ajbspi-37615	63	30	pages	page	NOUN
ajbspi-37615	63	31	:	:	PUNCT
ajbspi-37615	63	32	10	10	NUM
ajbspi-37615	63	33	-	-	SYM
ajbspi-37615	63	34	15	15	NUM
ajbspi-37615	63	35	sjif	sjif	NOUN
ajbspi-37615	63	36	impact	impact	NOUN
ajbspi-37615	63	37	factor	factor	NOUN
ajbspi-37615	63	38	(	(	PUNCT
ajbspi-37615	63	39	2021	2021	NUM
ajbspi-37615	63	40	:	:	PUNCT
ajbspi-37615	63	41	5	5	NUM
ajbspi-37615	63	42	.	.	NOUN
ajbspi-37615	63	43	705	705	NUM
ajbspi-37615	63	44	)	)	PUNCT
ajbspi-37615	63	45	(	(	PUNCT
ajbspi-37615	63	46	2022	2022	NUM
ajbspi-37615	63	47	:	:	PUNCT
ajbspi-37615	63	48	5	5	NUM
ajbspi-37615	63	49	.	.	NOUN
ajbspi-37615	63	50	705	705	NUM
ajbspi-37615	63	51	)	)	PUNCT
ajbspi-37615	63	52	(	(	PUNCT
ajbspi-37615	63	53	2023	2023	NUM
ajbspi-37615	63	54	:	:	PUNCT
ajbspi-37615	63	55	6.534	6.534	NUM
ajbspi-37615	63	56	)	)	PUNCT
ajbspi-37615	63	57	oclc	oclc	PROPN
ajbspi-37615	63	58	–	–	PUNCT
ajbspi-37615	63	59	1121105677	1121105677	NUM
ajbspi-37615	63	60	publisher	publisher	NOUN
ajbspi-37615	63	61	:	:	PUNCT
ajbspi-37615	63	62	oscar	oscar	NOUN
ajbspi-37615	63	63	publishing	publishing	NOUN
ajbspi-37615	63	64	services	service	NOUN
ajbspi-37615	63	65	servi	servi	VERB
ajbspi-37615	63	66	in	in	ADP
ajbspi-37615	63	67	vitro	vitro	X
ajbspi-37615	63	68	and	and	CCONJ
ajbspi-37615	63	69	in	in	ADP
ajbspi-37615	63	70	vivo	vivo	ADJ
ajbspi-37615	63	71	pharmacological	pharmacological	NOUN
ajbspi-37615	63	72	evaluations	evaluation	NOUN
ajbspi-37615	63	73	demonstrated	demonstrate	VERB
ajbspi-37615	63	74	that	that	SCONJ
ajbspi-37615	63	75	the	the	DET
ajbspi-37615	63	76	amide	amide	NOUN
ajbspi-37615	63	77	-	-	PUNCT
ajbspi-37615	63	78	based	base	VERB
ajbspi-37615	63	79	mutual	mutual	ADJ
ajbspi-37615	63	80	prodrug	prodrug	NOUN
ajbspi-37615	63	81	exhibited	exhibit	VERB
ajbspi-37615	63	82	enhanced	enhance	VERB
ajbspi-37615	63	83	pharmacological	pharmacological	ADJ
ajbspi-37615	63	84	activities	activity	NOUN
ajbspi-37615	63	85	compared	compare	VERB
ajbspi-37615	63	86	to	to	ADP
ajbspi-37615	63	87	the	the	DET
ajbspi-37615	63	88	parent	parent	NOUN
ajbspi-37615	63	89	drugs	drug	NOUN
ajbspi-37615	63	90	alone	alone	ADV
ajbspi-37615	63	91	.	.	PUNCT
ajbspi-37615	64	1	the	the	DET
ajbspi-37615	64	2	prodrug	prodrug	NOUN
ajbspi-37615	64	3	displayed	display	VERB
ajbspi-37615	64	4	improved	improved	ADJ
ajbspi-37615	64	5	potency	potency	NOUN
ajbspi-37615	64	6	,	,	PUNCT
ajbspi-37615	64	7	prolonged	prolonged	ADJ
ajbspi-37615	64	8	action	action	NOUN
ajbspi-37615	64	9	,	,	PUNCT
ajbspi-37615	64	10	and	and	CCONJ
ajbspi-37615	64	11	reduced	reduced	ADJ
ajbspi-37615	64	12	toxicity	toxicity	NOUN
ajbspi-37615	64	13	,	,	PUNCT
ajbspi-37615	64	14	suggesting	suggest	VERB
ajbspi-37615	64	15	potential	potential	ADJ
ajbspi-37615	64	16	therapeutic	therapeutic	ADJ
ajbspi-37615	64	17	advantages	advantage	NOUN
ajbspi-37615	64	18	over	over	ADP
ajbspi-37615	64	19	the	the	DET
ajbspi-37615	64	20	individual	individual	ADJ
ajbspi-37615	64	21	parent	parent	NOUN
ajbspi-37615	64	22	drugs	drug	NOUN
ajbspi-37615	64	23	.	.	PUNCT
ajbspi-37615	65	1	discussion	discussion	VERB
ajbspi-37615	65	2	the	the	DET
ajbspi-37615	65	3	synthesis	synthesis	NOUN
ajbspi-37615	65	4	and	and	CCONJ
ajbspi-37615	65	5	evaluation	evaluation	NOUN
ajbspi-37615	65	6	of	of	ADP
ajbspi-37615	65	7	the	the	DET
ajbspi-37615	65	8	amide	amide	NOUN
ajbspi-37615	65	9	-	-	PUNCT
ajbspi-37615	65	10	based	base	VERB
ajbspi-37615	65	11	mutual	mutual	ADJ
ajbspi-37615	65	12	prodrug	prodrug	NOUN
ajbspi-37615	65	13	revealed	reveal	VERB
ajbspi-37615	65	14	several	several	ADJ
ajbspi-37615	65	15	key	key	ADJ
ajbspi-37615	65	16	findings	finding	NOUN
ajbspi-37615	65	17	.	.	PUNCT
ajbspi-37615	66	1	the	the	DET
ajbspi-37615	66	2	successful	successful	ADJ
ajbspi-37615	66	3	synthesis	synthesis	NOUN
ajbspi-37615	66	4	of	of	ADP
ajbspi-37615	66	5	the	the	DET
ajbspi-37615	66	6	prodrug	prodrug	NOUN
ajbspi-37615	66	7	demonstrated	demonstrate	VERB
ajbspi-37615	66	8	the	the	DET
ajbspi-37615	66	9	feasibility	feasibility	NOUN
ajbspi-37615	66	10	of	of	ADP
ajbspi-37615	66	11	the	the	DET
ajbspi-37615	66	12	chemical	chemical	NOUN
ajbspi-37615	66	13	conjugation	conjugation	NOUN
ajbspi-37615	66	14	strategy	strategy	NOUN
ajbspi-37615	66	15	and	and	CCONJ
ajbspi-37615	66	16	its	its	PRON
ajbspi-37615	66	17	potential	potential	NOUN
ajbspi-37615	66	18	to	to	PART
ajbspi-37615	66	19	create	create	VERB
ajbspi-37615	66	20	novel	novel	ADJ
ajbspi-37615	66	21	pharmaceutical	pharmaceutical	ADJ
ajbspi-37615	66	22	entities	entity	NOUN
ajbspi-37615	66	23	.	.	PUNCT
ajbspi-37615	67	1	the	the	DET
ajbspi-37615	67	2	improved	improved	ADJ
ajbspi-37615	67	3	solubility	solubility	NOUN
ajbspi-37615	67	4	of	of	ADP
ajbspi-37615	67	5	the	the	DET
ajbspi-37615	67	6	prodrug	prodrug	NOUN
ajbspi-37615	67	7	indicated	indicate	VERB
ajbspi-37615	67	8	its	its	PRON
ajbspi-37615	67	9	potential	potential	NOUN
ajbspi-37615	67	10	for	for	ADP
ajbspi-37615	67	11	overcoming	overcome	VERB
ajbspi-37615	67	12	the	the	DET
ajbspi-37615	67	13	limitations	limitation	NOUN
ajbspi-37615	67	14	associated	associate	VERB
ajbspi-37615	67	15	with	with	ADP
ajbspi-37615	67	16	poor	poor	ADJ
ajbspi-37615	67	17	water	water	NOUN
ajbspi-37615	67	18	solubility	solubility	NOUN
ajbspi-37615	67	19	of	of	ADP
ajbspi-37615	67	20	many	many	ADJ
ajbspi-37615	67	21	drugs	drug	NOUN
ajbspi-37615	67	22	,	,	PUNCT
ajbspi-37615	67	23	which	which	PRON
ajbspi-37615	67	24	often	often	ADV
ajbspi-37615	67	25	hampers	hamper	VERB
ajbspi-37615	67	26	their	their	PRON
ajbspi-37615	67	27	clinical	clinical	ADJ
ajbspi-37615	67	28	applications	application	NOUN
ajbspi-37615	67	29	.	.	PUNCT
ajbspi-37615	68	1	the	the	DET
ajbspi-37615	68	2	in	in	ADV
ajbspi-37615	68	3	vitro	vitro	X
ajbspi-37615	68	4	release	release	NOUN
ajbspi-37615	68	5	kinetics	kinetic	NOUN
ajbspi-37615	68	6	of	of	ADP
ajbspi-37615	68	7	the	the	DET
ajbspi-37615	68	8	prodrug	prodrug	NOUN
ajbspi-37615	68	9	showcased	showcase	VERB
ajbspi-37615	68	10	a	a	DET
ajbspi-37615	68	11	controlled	control	VERB
ajbspi-37615	68	12	and	and	CCONJ
ajbspi-37615	68	13	sustained	sustained	ADJ
ajbspi-37615	68	14	release	release	NOUN
ajbspi-37615	68	15	of	of	ADP
ajbspi-37615	68	16	active	active	ADJ
ajbspi-37615	68	17	moieties	moiety	NOUN
ajbspi-37615	68	18	.	.	PUNCT
ajbspi-37615	69	1	this	this	DET
ajbspi-37615	69	2	sustained	sustain	VERB
ajbspi-37615	69	3	release	release	NOUN
ajbspi-37615	69	4	profile	profile	NOUN
ajbspi-37615	69	5	could	could	AUX
ajbspi-37615	69	6	result	result	VERB
ajbspi-37615	69	7	in	in	ADP
ajbspi-37615	69	8	reduced	reduced	ADJ
ajbspi-37615	69	9	dosing	dose	VERB
ajbspi-37615	69	10	frequency	frequency	NOUN
ajbspi-37615	69	11	and	and	CCONJ
ajbspi-37615	69	12	improved	improve	VERB
ajbspi-37615	69	13	patient	patient	ADJ
ajbspi-37615	69	14	compliance	compliance	NOUN
ajbspi-37615	69	15	.	.	PUNCT
ajbspi-37615	70	1	moreover	moreover	ADV
ajbspi-37615	70	2	,	,	PUNCT
ajbspi-37615	70	3	the	the	DET
ajbspi-37615	70	4	enzymatic	enzymatic	ADJ
ajbspi-37615	70	5	hydrolysis	hydrolysis	NOUN
ajbspi-37615	70	6	studies	study	NOUN
ajbspi-37615	70	7	confirmed	confirm	VERB
ajbspi-37615	70	8	the	the	DET
ajbspi-37615	70	9	prodrug	prodrug	NOUN
ajbspi-37615	70	10	's	's	PART
ajbspi-37615	70	11	biodegradability	biodegradability	NOUN
ajbspi-37615	70	12	,	,	PUNCT
ajbspi-37615	70	13	suggesting	suggest	VERB
ajbspi-37615	70	14	that	that	SCONJ
ajbspi-37615	70	15	it	it	PRON
ajbspi-37615	70	16	could	could	AUX
ajbspi-37615	70	17	release	release	VERB
ajbspi-37615	70	18	the	the	DET
ajbspi-37615	70	19	parent	parent	NOUN
ajbspi-37615	70	20	drugs	drug	NOUN
ajbspi-37615	70	21	in	in	ADP
ajbspi-37615	70	22	a	a	DET
ajbspi-37615	70	23	biocompatible	biocompatible	ADJ
ajbspi-37615	70	24	manner	manner	NOUN
ajbspi-37615	70	25	.	.	PUNCT
ajbspi-37615	71	1	the	the	DET
ajbspi-37615	71	2	pharmacological	pharmacological	ADJ
ajbspi-37615	71	3	evaluation	evaluation	NOUN
ajbspi-37615	71	4	of	of	ADP
ajbspi-37615	71	5	the	the	DET
ajbspi-37615	71	6	amidebased	amidebase	VERB
ajbspi-37615	71	7	mutual	mutual	ADJ
ajbspi-37615	71	8	prodrug	prodrug	NOUN
ajbspi-37615	71	9	provided	provide	VERB
ajbspi-37615	71	10	compelling	compelling	ADJ
ajbspi-37615	71	11	evidence	evidence	NOUN
ajbspi-37615	71	12	for	for	ADP
ajbspi-37615	71	13	its	its	PRON
ajbspi-37615	71	14	enhanced	enhanced	ADJ
ajbspi-37615	71	15	efficacy	efficacy	NOUN
ajbspi-37615	71	16	and	and	CCONJ
ajbspi-37615	71	17	reduced	reduce	VERB
ajbspi-37615	71	18	toxicity	toxicity	NOUN
ajbspi-37615	71	19	compared	compare	VERB
ajbspi-37615	71	20	to	to	ADP
ajbspi-37615	71	21	the	the	DET
ajbspi-37615	71	22	individual	individual	ADJ
ajbspi-37615	71	23	parent	parent	NOUN
ajbspi-37615	71	24	drugs	drug	NOUN
ajbspi-37615	71	25	.	.	PUNCT
ajbspi-37615	72	1	this	this	DET
ajbspi-37615	72	2	finding	finding	NOUN
ajbspi-37615	72	3	suggests	suggest	VERB
ajbspi-37615	72	4	that	that	SCONJ
ajbspi-37615	72	5	the	the	DET
ajbspi-37615	72	6	mutual	mutual	ADJ
ajbspi-37615	72	7	prodrug	prodrug	NOUN
ajbspi-37615	72	8	formulation	formulation	NOUN
ajbspi-37615	72	9	may	may	AUX
ajbspi-37615	72	10	offer	offer	VERB
ajbspi-37615	72	11	a	a	DET
ajbspi-37615	72	12	synergistic	synergistic	ADJ
ajbspi-37615	72	13	effect	effect	NOUN
ajbspi-37615	72	14	or	or	CCONJ
ajbspi-37615	72	15	other	other	ADJ
ajbspi-37615	72	16	advantages	advantage	NOUN
ajbspi-37615	72	17	over	over	ADP
ajbspi-37615	72	18	the	the	DET
ajbspi-37615	72	19	conventional	conventional	ADJ
ajbspi-37615	72	20	co	co	NOUN
ajbspi-37615	72	21	-	-	NOUN
ajbspi-37615	72	22	administration	administration	NOUN
ajbspi-37615	72	23	of	of	ADP
ajbspi-37615	72	24	the	the	DET
ajbspi-37615	72	25	parent	parent	NOUN
ajbspi-37615	72	26	drugs	drug	NOUN
ajbspi-37615	72	27	.	.	PUNCT
ajbspi-37615	73	1	conclusion	conclusion	NOUN
ajbspi-37615	73	2	in	in	ADP
ajbspi-37615	73	3	conclusion	conclusion	NOUN
ajbspi-37615	73	4	,	,	PUNCT
ajbspi-37615	73	5	the	the	DET
ajbspi-37615	73	6	synthesis	synthesis	NOUN
ajbspi-37615	73	7	and	and	CCONJ
ajbspi-37615	73	8	evaluation	evaluation	NOUN
ajbspi-37615	73	9	of	of	ADP
ajbspi-37615	73	10	the	the	DET
ajbspi-37615	73	11	amide	amide	NOUN
ajbspi-37615	73	12	-	-	PUNCT
ajbspi-37615	73	13	based	base	VERB
ajbspi-37615	73	14	mutual	mutual	ADJ
ajbspi-37615	73	15	prodrug	prodrug	NOUN
ajbspi-37615	73	16	demonstrated	demonstrate	VERB
ajbspi-37615	73	17	its	its	PRON
ajbspi-37615	73	18	potential	potential	NOUN
ajbspi-37615	73	19	as	as	ADP
ajbspi-37615	73	20	an	an	DET
ajbspi-37615	73	21	innovative	innovative	ADJ
ajbspi-37615	73	22	drug	drug	NOUN
ajbspi-37615	73	23	delivery	delivery	NOUN
ajbspi-37615	73	24	system	system	NOUN
ajbspi-37615	73	25	.	.	PUNCT
ajbspi-37615	74	1	the	the	DET
ajbspi-37615	74	2	prodrug	prodrug	NOUN
ajbspi-37615	74	3	exhibited	exhibit	VERB
ajbspi-37615	74	4	improved	improve	VERB
ajbspi-37615	74	5	physicochemical	physicochemical	ADJ
ajbspi-37615	74	6	properties	property	NOUN
ajbspi-37615	74	7	,	,	PUNCT
ajbspi-37615	74	8	controlled	control	VERB
ajbspi-37615	74	9	release	release	NOUN
ajbspi-37615	74	10	kinetics	kinetic	NOUN
ajbspi-37615	74	11	,	,	PUNCT
ajbspi-37615	74	12	and	and	CCONJ
ajbspi-37615	74	13	enhanced	enhanced	ADJ
ajbspi-37615	74	14	pharmacological	pharmacological	ADJ
ajbspi-37615	74	15	activities	activity	NOUN
ajbspi-37615	74	16	compared	compare	VERB
ajbspi-37615	74	17	to	to	ADP
ajbspi-37615	74	18	the	the	DET
ajbspi-37615	74	19	individual	individual	ADJ
ajbspi-37615	74	20	parent	parent	NOUN
ajbspi-37615	74	21	drugs	drug	NOUN
ajbspi-37615	74	22	.	.	PUNCT
ajbspi-37615	75	1	these	these	DET
ajbspi-37615	75	2	findings	finding	NOUN
ajbspi-37615	75	3	indicate	indicate	VERB
ajbspi-37615	75	4	that	that	SCONJ
ajbspi-37615	75	5	the	the	DET
ajbspi-37615	75	6	amidebased	amidebase	VERB
ajbspi-37615	75	7	mutual	mutual	ADJ
ajbspi-37615	75	8	prodrug	prodrug	NOUN
ajbspi-37615	75	9	holds	hold	VERB
ajbspi-37615	75	10	promise	promise	NOUN
ajbspi-37615	75	11	as	as	ADP
ajbspi-37615	75	12	a	a	DET
ajbspi-37615	75	13	viable	viable	ADJ
ajbspi-37615	75	14	strategy	strategy	NOUN
ajbspi-37615	75	15	to	to	PART
ajbspi-37615	75	16	optimize	optimize	VERB
ajbspi-37615	75	17	drug	drug	NOUN
ajbspi-37615	75	18	delivery	delivery	NOUN
ajbspi-37615	75	19	and	and	CCONJ
ajbspi-37615	75	20	improve	improve	VERB
ajbspi-37615	75	21	therapeutic	therapeutic	ADJ
ajbspi-37615	75	22	outcomes	outcome	NOUN
ajbspi-37615	75	23	.	.	PUNCT
ajbspi-37615	76	1	the	the	DET
ajbspi-37615	76	2	results	result	NOUN
ajbspi-37615	76	3	of	of	ADP
ajbspi-37615	76	4	this	this	DET
ajbspi-37615	76	5	study	study	NOUN
ajbspi-37615	76	6	contribute	contribute	VERB
ajbspi-37615	76	7	valuable	valuable	ADJ
ajbspi-37615	76	8	insights	insight	NOUN
ajbspi-37615	76	9	into	into	ADP
ajbspi-37615	76	10	the	the	DET
ajbspi-37615	76	11	design	design	NOUN
ajbspi-37615	76	12	and	and	CCONJ
ajbspi-37615	76	13	development	development	NOUN
ajbspi-37615	76	14	of	of	ADP
ajbspi-37615	76	15	amidebased	amidebase	VERB
ajbspi-37615	76	16	mutual	mutual	ADJ
ajbspi-37615	76	17	prodrugs	prodrug	NOUN
ajbspi-37615	76	18	.	.	PUNCT
ajbspi-37615	77	1	the	the	DET
ajbspi-37615	77	2	enhanced	enhanced	ADJ
ajbspi-37615	77	3	solubility	solubility	NOUN
ajbspi-37615	77	4	,	,	PUNCT
ajbspi-37615	77	5	controlled	control	VERB
ajbspi-37615	77	6	release	release	NOUN
ajbspi-37615	77	7	,	,	PUNCT
ajbspi-37615	77	8	and	and	CCONJ
ajbspi-37615	77	9	improved	improve	VERB
ajbspi-37615	77	10	pharmacological	pharmacological	NOUN
ajbspi-37615	77	11	properties	property	NOUN
ajbspi-37615	77	12	make	make	VERB
ajbspi-37615	77	13	the	the	DET
ajbspi-37615	77	14	prodrug	prodrug	NOUN
ajbspi-37615	77	15	a	a	DET
ajbspi-37615	77	16	promising	promising	ADJ
ajbspi-37615	77	17	candidate	candidate	NOUN
ajbspi-37615	77	18	for	for	ADP
ajbspi-37615	77	19	further	further	ADJ
ajbspi-37615	77	20	optimization	optimization	NOUN
ajbspi-37615	77	21	and	and	CCONJ
ajbspi-37615	77	22	potential	potential	ADJ
ajbspi-37615	77	23	clinical	clinical	ADJ
ajbspi-37615	77	24	applications	application	NOUN
ajbspi-37615	77	25	.	.	PUNCT
ajbspi-37615	78	1	overall	overall	ADV
ajbspi-37615	78	2	,	,	PUNCT
ajbspi-37615	78	3	this	this	DET
ajbspi-37615	78	4	research	research	NOUN
ajbspi-37615	78	5	underscores	underscore	VERB
ajbspi-37615	78	6	the	the	DET
ajbspi-37615	78	7	significance	significance	NOUN
ajbspi-37615	78	8	of	of	ADP
ajbspi-37615	78	9	prodrug	prodrug	NOUN
ajbspi-37615	78	10	-	-	PUNCT
ajbspi-37615	78	11	based	base	VERB
ajbspi-37615	78	12	approaches	approach	NOUN
ajbspi-37615	78	13	in	in	ADP
ajbspi-37615	78	14	pharmaceutical	pharmaceutical	ADJ
ajbspi-37615	78	15	research	research	NOUN
ajbspi-37615	78	16	and	and	CCONJ
ajbspi-37615	78	17	presents	present	VERB
ajbspi-37615	78	18	the	the	DET
ajbspi-37615	78	19	amidebased	amidebase	VERB
ajbspi-37615	78	20	mutual	mutual	ADJ
ajbspi-37615	78	21	prodrug	prodrug	NOUN
ajbspi-37615	78	22	as	as	ADP
ajbspi-37615	78	23	a	a	DET
ajbspi-37615	78	24	potential	potential	ADJ
ajbspi-37615	78	25	platform	platform	NOUN
ajbspi-37615	78	26	for	for	ADP
ajbspi-37615	78	27	advancing	advance	VERB
ajbspi-37615	78	28	drug	drug	NOUN
ajbspi-37615	78	29	delivery	delivery	NOUN
ajbspi-37615	78	30	and	and	CCONJ
ajbspi-37615	78	31	therapeutic	therapeutic	ADJ
ajbspi-37615	78	32	efficacy	efficacy	NOUN
ajbspi-37615	78	33	.	.	PUNCT
ajbspi-37615	79	1	future	future	ADJ
ajbspi-37615	79	2	investigations	investigation	NOUN
ajbspi-37615	79	3	could	could	AUX
ajbspi-37615	79	4	focus	focus	VERB
ajbspi-37615	79	5	on	on	ADP
ajbspi-37615	79	6	optimizing	optimize	VERB
ajbspi-37615	79	7	the	the	DET
ajbspi-37615	79	8	prodrug	prodrug	NOUN
ajbspi-37615	79	9	formulation	formulation	NOUN
ajbspi-37615	79	10	,	,	PUNCT
ajbspi-37615	79	11	conducting	conduct	VERB
ajbspi-37615	79	12	additional	additional	ADJ
ajbspi-37615	79	13	in	in	ADP
ajbspi-37615	79	14	vivo	vivo	ADJ
ajbspi-37615	79	15	studies	study	NOUN
ajbspi-37615	79	16	,	,	PUNCT
ajbspi-37615	79	17	and	and	CCONJ
ajbspi-37615	79	18	exploring	explore	VERB
ajbspi-37615	79	19	its	its	PRON
ajbspi-37615	79	20	application	application	NOUN
ajbspi-37615	79	21	for	for	ADP
ajbspi-37615	79	22	specific	specific	ADJ
ajbspi-37615	79	23	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	NOUN
ajbspi-37615	79	24	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	AUX
ajbspi-37615	79	25	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	ADJ
ajbspi-37615	79	26	volume	volume	NOUN
ajbspi-37615	79	27	03	03	NUM
ajbspi-37615	79	28	issue	issue	NOUN
ajbspi-37615	79	29	08	08	NUM
ajbspi-37615	79	30	-	-	SYM
ajbspi-37615	79	31	2023	2023	NUM
ajbspi-37615	79	32	15	15	NUM
ajbspi-37615	79	33	american	american	ADJ
ajbspi-37615	79	34	journal	journal	PROPN
ajbspi-37615	79	35	of	of	ADP
ajbspi-37615	79	36	biomedical	biomedical	PROPN
ajbspi-37615	79	37	science	science	PROPN
ajbspi-37615	79	38	&	&	CCONJ
ajbspi-37615	79	39	pharmaceutical	pharmaceutical	PROPN
ajbspi-37615	79	40	innovation	innovation	NOUN
ajbspi-37615	79	41	(	(	PUNCT
ajbspi-37615	79	42	issn	issn	PROPN
ajbspi-37615	79	43	–	–	PUNCT
ajbspi-37615	79	44	2771	2771	NUM
ajbspi-37615	79	45	-	-	SYM
ajbspi-37615	79	46	2753	2753	NUM
ajbspi-37615	79	47	)	)	PUNCT
ajbspi-37615	79	48	volume	volume	NOUN
ajbspi-37615	79	49	03	03	NUM
ajbspi-37615	79	50	issue	issue	NOUN
ajbspi-37615	79	51	08	08	NUM
ajbspi-37615	79	52	pages	page	NOUN
ajbspi-37615	79	53	:	:	PUNCT
ajbspi-37615	79	54	10	10	NUM
ajbspi-37615	79	55	-	-	SYM
ajbspi-37615	79	56	15	15	NUM
ajbspi-37615	79	57	sjif	sjif	NOUN
ajbspi-37615	79	58	impact	impact	NOUN
ajbspi-37615	79	59	factor	factor	NOUN
ajbspi-37615	79	60	(	(	PUNCT
ajbspi-37615	79	61	2021	2021	NUM
ajbspi-37615	79	62	:	:	PUNCT
ajbspi-37615	79	63	5	5	NUM
ajbspi-37615	79	64	.	.	NOUN
ajbspi-37615	79	65	705	705	NUM
ajbspi-37615	79	66	)	)	PUNCT
ajbspi-37615	79	67	(	(	PUNCT
ajbspi-37615	79	68	2022	2022	NUM
ajbspi-37615	79	69	:	:	PUNCT
ajbspi-37615	79	70	5	5	NUM
ajbspi-37615	79	71	.	.	NOUN
ajbspi-37615	79	72	705	705	NUM
ajbspi-37615	79	73	)	)	PUNCT
ajbspi-37615	79	74	(	(	PUNCT
ajbspi-37615	79	75	2023	2023	NUM
ajbspi-37615	79	76	:	:	PUNCT
ajbspi-37615	79	77	6.534	6.534	NUM
ajbspi-37615	79	78	)	)	PUNCT
ajbspi-37615	79	79	oclc	oclc	PROPN
ajbspi-37615	79	80	–	–	PUNCT
ajbspi-37615	79	81	1121105677	1121105677	NUM
ajbspi-37615	79	82	publisher	publisher	NOUN
ajbspi-37615	79	83	:	:	PUNCT
ajbspi-37615	79	84	oscar	oscar	NOUN
ajbspi-37615	79	85	publishing	publishing	NOUN
ajbspi-37615	79	86	services	service	NOUN
ajbspi-37615	79	87	servi	servi	VERB
ajbspi-37615	79	88	therapeutic	therapeutic	ADJ
ajbspi-37615	79	89	targets	target	NOUN
ajbspi-37615	79	90	,	,	PUNCT
ajbspi-37615	79	91	paving	pave	VERB
ajbspi-37615	79	92	the	the	DET
ajbspi-37615	79	93	way	way	NOUN
ajbspi-37615	79	94	for	for	ADP
ajbspi-37615	79	95	innovative	innovative	ADJ
ajbspi-37615	79	96	drug	drug	NOUN
ajbspi-37615	79	97	delivery	delivery	NOUN
ajbspi-37615	79	98	strategies	strategy	NOUN
ajbspi-37615	79	99	in	in	ADP
ajbspi-37615	79	100	the	the	DET
ajbspi-37615	79	101	pharmaceutical	pharmaceutical	ADJ
ajbspi-37615	79	102	industry	industry	NOUN
ajbspi-37615	79	103	.	.	PUNCT
ajbspi-37615	80	1	references	reference	NOUN
ajbspi-37615	80	2	1	1	NUM
ajbspi-37615	80	3	.	.	PUNCT
ajbspi-37615	80	4	kristiina	kristiina	PROPN
ajbspi-37615	80	5	m.	m.	PROPN
ajbspi-37615	80	6	huttunen	huttunen	PROPN
ajbspi-37615	80	7	,	,	PUNCT
ajbspi-37615	80	8	hannu	hannu	PROPN
ajbspi-37615	80	9	raunio	raunio	PROPN
ajbspi-37615	80	10	and	and	CCONJ
ajbspi-37615	80	11	jarkko	jarkko	PROPN
ajbspi-37615	80	12	rautio	rautio	PROPN
ajbspi-37615	80	13	,	,	PUNCT
ajbspi-37615	80	14	prodrugs	prodrug	NOUN
ajbspi-37615	80	15	—	—	PUNCT
ajbspi-37615	80	16	from	from	ADP
ajbspi-37615	80	17	serendipity	serendipity	NOUN
ajbspi-37615	80	18	to	to	ADP
ajbspi-37615	80	19	rational	rational	ADJ
ajbspi-37615	80	20	design	design	NOUN
ajbspi-37615	80	21	,	,	PUNCT
ajbspi-37615	80	22	pharmacological	pharmacological	ADJ
ajbspi-37615	80	23	reviews	review	NOUN
ajbspi-37615	80	24	,	,	PUNCT
ajbspi-37615	80	25	2011	2011	NUM
ajbspi-37615	80	26	,	,	PUNCT
ajbspi-37615	80	27	63(3	63(3	NUM
ajbspi-37615	80	28	)	)	PUNCT
ajbspi-37615	80	29	,	,	PUNCT
ajbspi-37615	80	30	750	750	NUM
ajbspi-37615	80	31	-	-	SYM
ajbspi-37615	80	32	71	71	NUM
ajbspi-37615	80	33	.	.	NOUN
ajbspi-37615	81	1	2	2	NUM
ajbspi-37615	81	2	.	.	PUNCT
ajbspi-37615	81	3	jarkko	jarkko	PROPN
ajbspi-37615	81	4	rautio	rautio	PROPN
ajbspi-37615	81	5	,	,	PUNCT
ajbspi-37615	81	6	hanna	hanna	PROPN
ajbspi-37615	81	7	kumpulainen	kumpulainen	PROPN
ajbspi-37615	81	8	,	,	PUNCT
ajbspi-37615	81	9	tycho	tycho	PROPN
ajbspi-37615	81	10	heimbach	heimbach	PROPN
ajbspi-37615	81	11	,	,	PUNCT
ajbspi-37615	81	12	reza	reza	PROPN
ajbspi-37615	81	13	oliyai	oliyai	PROPN
ajbspi-37615	81	14	,	,	PUNCT
ajbspi-37615	81	15	dooman	dooman	ADJ
ajbspi-37615	81	16	oh	oh	INTJ
ajbspi-37615	81	17	,	,	PUNCT
ajbspi-37615	81	18	tomi	tomi	PROPN
ajbspi-37615	81	19	järvinen	järvinen	PROPN
ajbspi-37615	81	20	&	&	CCONJ
ajbspi-37615	81	21	jouko	jouko	PROPN
ajbspi-37615	81	22	savolainen	savolainen	PROPN
ajbspi-37615	81	23	prodrugs	prodrug	NOUN
ajbspi-37615	81	24	:	:	PUNCT
ajbspi-37615	81	25	design	design	NOUN
ajbspi-37615	81	26	and	and	CCONJ
ajbspi-37615	81	27	clinical	clinical	ADJ
ajbspi-37615	81	28	applications	application	NOUN
ajbspi-37615	81	29	.	.	PUNCT
ajbspi-37615	82	1	nature	nature	NOUN
ajbspi-37615	82	2	reviews	review	VERB
ajbspi-37615	82	3	drug	drug	NOUN
ajbspi-37615	82	4	discovery	discovery	PROPN
ajbspi-37615	82	5	2008	2008	NUM
ajbspi-37615	82	6	,	,	PUNCT
ajbspi-37615	82	7	7	7	NUM
ajbspi-37615	82	8	,	,	PUNCT
ajbspi-37615	82	9	255	255	NUM
ajbspi-37615	82	10	-	-	SYM
ajbspi-37615	82	11	70	70	NUM
ajbspi-37615	82	12	.	.	PUNCT
ajbspi-37615	83	1	3	3	X
ajbspi-37615	83	2	.	.	PUNCT
ajbspi-37615	83	3	jana	jana	PROPN
ajbspi-37615	83	4	s	s	PROPN
ajbspi-37615	83	5	,	,	PUNCT
ajbspi-37615	83	6	mandlekar	mandlekar	NOUN
ajbspi-37615	83	7	s	s	PART
ajbspi-37615	83	8	,	,	PUNCT
ajbspi-37615	83	9	marathe	marathe	ADJ
ajbspi-37615	83	10	p.	p.	NOUN
ajbspi-37615	83	11	prodrug	prodrug	NOUN
ajbspi-37615	83	12	design	design	NOUN
ajbspi-37615	83	13	to	to	PART
ajbspi-37615	83	14	improve	improve	VERB
ajbspi-37615	83	15	pharmacokinetic	pharmacokinetic	ADJ
ajbspi-37615	83	16	and	and	CCONJ
ajbspi-37615	83	17	drug	drug	NOUN
ajbspi-37615	83	18	delivery	delivery	NOUN
ajbspi-37615	83	19	properties	property	NOUN
ajbspi-37615	83	20	:	:	PUNCT
ajbspi-37615	83	21	challenges	challenge	NOUN
ajbspi-37615	83	22	to	to	ADP
ajbspi-37615	83	23	the	the	DET
ajbspi-37615	83	24	discovery	discovery	NOUN
ajbspi-37615	83	25	scientists.curr	scientists.curr	PROPN
ajbspi-37615	83	26	med	med	PROPN
ajbspi-37615	83	27	chem	chem	NOUN
ajbspi-37615	83	28	.	.	PUNCT
ajbspi-37615	84	1	2010;17(32):3874	2010;17(32):3874	NUM
ajbspi-37615	84	2	-	-	SYM
ajbspi-37615	84	3	908	908	NUM
ajbspi-37615	84	4	.	.	PUNCT
ajbspi-37615	85	1	4	4	NUM
ajbspi-37615	85	2	.	.	X
ajbspi-37615	85	3	bhosle	bhosle	PROPN
ajbspi-37615	85	4	,	,	PUNCT
ajbspi-37615	85	5	d.	d.	PROPN
ajbspi-37615	85	6	;	;	PUNCT
ajbspi-37615	85	7	bharambe	bharambe	ADV
ajbspi-37615	85	8	,	,	PUNCT
ajbspi-37615	85	9	s.	s.	PROPN
ajbspi-37615	85	10	;	;	PUNCT
ajbspi-37615	85	11	gairola	gairola	PROPN
ajbspi-37615	85	12	,	,	PUNCT
ajbspi-37615	85	13	neha	neha	NOUN
ajbspi-37615	85	14	;	;	PUNCT
ajbspi-37615	85	15	dhaneshwar	dhaneshwar	NOUN
ajbspi-37615	85	16	,	,	PUNCT
ajbspi-37615	85	17	suneela	suneela	PROPN
ajbspi-37615	85	18	s.	s.	PROPN
ajbspi-37615	85	19	mutual	mutual	ADJ
ajbspi-37615	85	20	prodrug	prodrug	NOUN
ajbspi-37615	85	21	concept	concept	NOUN
ajbspi-37615	85	22	:	:	PUNCT
ajbspi-37615	85	23	fundamentals	fundamental	NOUN
ajbspi-37615	85	24	and	and	CCONJ
ajbspi-37615	85	25	applications	application	NOUN
ajbspi-37615	85	26	,	,	PUNCT
ajbspi-37615	85	27	ind	ind	PROPN
ajbspi-37615	85	28	.	.	PUNCT
ajbspi-37615	86	1	j.	j.	PROPN
ajbspi-37615	86	2	pharm	pharm	PROPN
ajbspi-37615	86	3	.	.	PUNCT
ajbspi-37615	87	1	sci	sci	PROPN
ajbspi-37615	87	2	.	.	PROPN
ajbspi-37615	87	3	,	,	PUNCT
ajbspi-37615	87	4	2006	2006	NUM
ajbspi-37615	87	5	,	,	PUNCT
ajbspi-37615	87	6	68(3	68(3	NUM
ajbspi-37615	87	7	)	)	PUNCT
ajbspi-37615	87	8	,	,	PUNCT
ajbspi-37615	87	9	286	286	NUM
ajbspi-37615	87	10	.	.	NOUN
ajbspi-37615	88	1	5	5	NUM
ajbspi-37615	88	2	.	.	X
ajbspi-37615	88	3	asif	asif	PROPN
ajbspi-37615	88	4	husain	husain	PROPN
ajbspi-37615	88	5	,	,	PUNCT
ajbspi-37615	88	6	priyanka	priyanka	PROPN
ajbspi-37615	88	7	ahuja	ahuja	PROPN
ajbspi-37615	88	8	,	,	PUNCT
ajbspi-37615	88	9	m.	m.	NOUN
ajbspi-37615	88	10	shaharyar	shaharyar	PROPN
ajbspi-37615	88	11	,	,	PUNCT
ajbspi-37615	88	12	aftab	aftab	PROPN
ajbspi-37615	88	13	ahmad	ahmad	PROPN
ajbspi-37615	88	14	,	,	PUNCT
ajbspi-37615	88	15	ibraheem	ibraheem	PROPN
ajbspi-37615	88	16	ahmed	ahmed	PROPN
ajbspi-37615	88	17	i.	i.	PROPN
ajbspi-37615	88	18	mkhalid	mkhalid	PROPN
ajbspi-37615	88	19	,	,	PUNCT
ajbspi-37615	88	20	m.m	m.m	PROPN
ajbspi-37615	88	21	.	.	PROPN
ajbspi-37615	88	22	alam	alam	PROPN
ajbspi-37615	88	23	,	,	PUNCT
ajbspi-37615	88	24	m.	m.	NOUN
ajbspi-37615	88	25	akhter	akhter	NOUN
ajbspi-37615	88	26	,	,	PUNCT
ajbspi-37615	88	27	and	and	CCONJ
ajbspi-37615	88	28	m.s	m.s	PROPN
ajbspi-37615	88	29	.	.	PROPN
ajbspi-37615	88	30	zaman	zaman	PROPN
ajbspi-37615	88	31	(	(	PUNCT
ajbspi-37615	88	32	2014	2014	NUM
ajbspi-37615	88	33	)	)	PUNCT
ajbspi-37615	88	34	,	,	PUNCT
ajbspi-37615	88	35	synthesis	synthesis	NOUN
ajbspi-37615	88	36	,	,	PUNCT
ajbspi-37615	88	37	biological	biological	ADJ
ajbspi-37615	88	38	activities	activity	NOUN
ajbspi-37615	88	39	and	and	CCONJ
ajbspi-37615	88	40	pharmacokinetics	pharmacokinetic	NOUN
ajbspi-37615	88	41	studies	study	NOUN
ajbspi-37615	88	42	of	of	ADP
ajbspi-37615	88	43	a	a	DET
ajbspi-37615	88	44	mutual	mutual	ADJ
ajbspi-37615	88	45	prodrug	prodrug	NOUN
ajbspi-37615	88	46	of	of	ADP
ajbspi-37615	88	47	aceclofenac	aceclofenac	NOUN
ajbspi-37615	88	48	and	and	CCONJ
ajbspi-37615	88	49	paracetamol	paracetamol	NOUN
ajbspi-37615	88	50	.	.	PUNCT
ajbspi-37615	89	1	med	med	PROPN
ajbspi-37615	89	2	.	.	PROPN
ajbspi-37615	89	3	chem	chem	PROPN
ajbspi-37615	89	4	.	.	PUNCT
ajbspi-37615	90	1	res	re	NOUN
ajbspi-37615	90	2	.	.	PROPN
ajbspi-37615	90	3	,	,	PUNCT
ajbspi-37615	90	4	23(3	23(3	NUM
ajbspi-37615	90	5	)	)	PUNCT
ajbspi-37615	90	6	1077	1077	NUM
ajbspi-37615	90	7	-	-	SYM
ajbspi-37615	90	8	1083	1083	NUM
ajbspi-37615	90	9	.	.	PUNCT
ajbspi-37615	91	1	6	6	NUM
ajbspi-37615	91	2	.	.	X
ajbspi-37615	91	3	halen	halen	PROPN
ajbspi-37615	91	4	pk	pk	PROPN
ajbspi-37615	91	5	,	,	PUNCT
ajbspi-37615	91	6	murumkar	murumkar	NOUN
ajbspi-37615	91	7	pr	pr	PROPN
ajbspi-37615	91	8	,	,	PUNCT
ajbspi-37615	91	9	yadav	yadav	PROPN
ajbspi-37615	91	10	mr	mr	PROPN
ajbspi-37615	91	11	,	,	PUNCT
ajbspi-37615	91	12	giridhar	giridhar	PROPN
ajbspi-37615	91	13	r.	r.	PROPN
ajbspi-37615	91	14	,	,	PUNCT
ajbspi-37615	91	15	prodrug	prodrug	NOUN
ajbspi-37615	91	16	designing	designing	NOUN
ajbspi-37615	91	17	of	of	ADP
ajbspi-37615	91	18	nsaids	nsaid	NOUN
ajbspi-37615	91	19	.	.	PUNCT
ajbspi-37615	92	1	mini	mini	PROPN
ajbspi-37615	92	2	rev	rev	PROPN
ajbspi-37615	92	3	.	.	PROPN
ajbspi-37615	92	4	med	med	PROPN
ajbspi-37615	92	5	.	.	PROPN
ajbspi-37615	92	6	chem	chem	PROPN
ajbspi-37615	92	7	,	,	PUNCT
ajbspi-37615	92	8	2009	2009	NUM
ajbspi-37615	92	9	;	;	PUNCT
ajbspi-37615	92	10	9(1	9(1	NUM
ajbspi-37615	92	11	):	):	PUNCT
ajbspi-37615	92	12	124	124	NUM
ajbspi-37615	92	13	-	-	SYM
ajbspi-37615	92	14	39	39	NUM
ajbspi-37615	92	15	.	.	PUNCT
ajbspi-37615	93	1	7	7	X
ajbspi-37615	93	2	.	.	X
ajbspi-37615	93	3	davies	davy	NOUN
ajbspi-37615	93	4	j.	j.	PROPN
ajbspi-37615	93	5	nature	nature	PROPN
ajbspi-37615	93	6	,	,	PUNCT
ajbspi-37615	93	7	1996	1996	NUM
ajbspi-37615	93	8	;	;	PUNCT
ajbspi-37615	93	9	383	383	NUM
ajbspi-37615	93	10	:	:	PUNCT
ajbspi-37615	93	11	219	219	NUM
ajbspi-37615	93	12	-	-	SYM
ajbspi-37615	93	13	20	20	NUM
ajbspi-37615	93	14	.	.	NOUN
ajbspi-37615	93	15	8	8	NUM
ajbspi-37615	93	16	.	.	X
ajbspi-37615	93	17	zaman	zaman	PROPN
ajbspi-37615	93	18	k.	k.	PROPN
ajbspi-37615	93	19	,	,	PUNCT
ajbspi-37615	93	20	tuberculosis	tuberculosis	NOUN
ajbspi-37615	93	21	:	:	PUNCT
ajbspi-37615	93	22	a	a	DET
ajbspi-37615	93	23	global	global	ADJ
ajbspi-37615	93	24	health	health	NOUN
ajbspi-37615	93	25	problem	problem	NOUN
ajbspi-37615	93	26	,	,	PUNCT
ajbspi-37615	93	27	j	j	PROPN
ajbspi-37615	93	28	health	health	PROPN
ajbspi-37615	93	29	popul	popul	PROPN
ajbspi-37615	93	30	nutr	nutr	PROPN
ajbspi-37615	93	31	.	.	PROPN
ajbspi-37615	93	32	,	,	PUNCT
ajbspi-37615	93	33	2010	2010	NUM
ajbspi-37615	93	34	,	,	PUNCT
ajbspi-37615	93	35	28(2	28(2	NUM
ajbspi-37615	93	36	)	)	PUNCT
ajbspi-37615	93	37	,	,	PUNCT
ajbspi-37615	93	38	111	111	NUM
ajbspi-37615	93	39	-	-	SYM
ajbspi-37615	93	40	13	13	NUM
ajbspi-37615	93	41	.	.	NOUN
ajbspi-37615	94	1	9	9	NUM
ajbspi-37615	94	2	.	.	X
ajbspi-37615	94	3	janin	janin	ADJ
ajbspi-37615	94	4	yl	yl	NOUN
ajbspi-37615	94	5	.	.	PUNCT
ajbspi-37615	95	1	antituberculosis	antituberculosis	NOUN
ajbspi-37615	95	2	drugs	drug	NOUN
ajbspi-37615	95	3	:	:	PUNCT
ajbspi-37615	95	4	ten	ten	NUM
ajbspi-37615	95	5	years	year	NOUN
ajbspi-37615	95	6	of	of	ADP
ajbspi-37615	95	7	research	research	NOUN
ajbspi-37615	95	8	.	.	PUNCT
ajbspi-37615	96	1	bioorg	bioorg	PROPN
ajbspi-37615	96	2	med	med	PROPN
ajbspi-37615	96	3	chem	chem	NOUN
ajbspi-37615	96	4	.	.	PUNCT
ajbspi-37615	97	1	2007	2007	NUM
ajbspi-37615	97	2	;	;	PUNCT
ajbspi-37615	97	3	15(7	15(7	NUM
ajbspi-37615	97	4	):	):	PUNCT
ajbspi-37615	97	5	2479513	2479513	NUM
ajbspi-37615	97	6	.	.	PUNCT
ajbspi-37615	98	1	10	10	NUM
ajbspi-37615	98	2	.	.	X
ajbspi-37615	99	1	shah	shah	PROPN
ajbspi-37615	99	2	ns	ns	PROPN
ajbspi-37615	99	3	,	,	PUNCT
ajbspi-37615	99	4	wright	wright	PROPN
ajbspi-37615	99	5	a	a	PROPN
ajbspi-37615	99	6	,	,	PUNCT
ajbspi-37615	99	7	bai	bai	PROPN
ajbspi-37615	99	8	gh	gh	PROPN
ajbspi-37615	99	9	,	,	PUNCT
ajbspi-37615	99	10	barrera	barrera	NOUN
ajbspi-37615	99	11	l	l	NOUN
ajbspi-37615	99	12	,	,	PUNCT
ajbspi-37615	99	13	boulahbal	boulahbal	PROPN
ajbspi-37615	99	14	f	f	PROPN
ajbspi-37615	99	15	,	,	PUNCT
ajbspi-37615	99	16	martin	martin	PROPN
ajbspi-37615	99	17	-	-	PUNCT
ajbspi-37615	99	18	casabona	casabona	PROPN
ajbspi-37615	99	19	n	n	CCONJ
ajbspi-37615	99	20	,	,	PUNCT
ajbspi-37615	99	21	et	et	PROPN
ajbspi-37615	99	22	al	al	PROPN
ajbspi-37615	99	23	.	.	PROPN
ajbspi-37615	100	1	worldwide	worldwide	PROPN
ajbspi-37615	100	2	emergence	emergence	NOUN
ajbspi-37615	100	3	of	of	ADP
ajbspi-37615	100	4	extensively	extensively	ADV
ajbspi-37615	100	5	drug	drug	NOUN
ajbspi-37615	100	6	-	-	PUNCT
ajbspi-37615	100	7	resistant	resistant	ADJ
ajbspi-37615	100	8	tuberculosis	tuberculosis	NOUN
ajbspi-37615	100	9	.	.	PUNCT
ajbspi-37615	101	1	emerg	emerg	PROPN
ajbspi-37615	101	2	infect	infect	NOUN
ajbspi-37615	101	3	dis.2007;13:380–7	dis.2007;13:380–7	PROPN
ajbspi-37615	101	4	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	PROPN
ajbspi-37615	101	5	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	NOUN
ajbspi-37615	101	6	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	NOUN