id	sid	tid	token	lemma	pos
ajbspi-57894	1	1	volume	volume	NOUN
ajbspi-57894	1	2	04	04	NUM
ajbspi-57894	1	3	issue	issue	NOUN
ajbspi-57894	1	4	11	11	NUM
ajbspi-57894	1	5	-	-	SYM
ajbspi-57894	1	6	2024	2024	NUM
ajbspi-57894	1	7	1	1	NUM
ajbspi-57894	1	8	american	american	ADJ
ajbspi-57894	1	9	journal	journal	NOUN
ajbspi-57894	1	10	of	of	ADP
ajbspi-57894	1	11	biomedical	biomedical	PROPN
ajbspi-57894	1	12	science	science	PROPN
ajbspi-57894	1	13	&	&	CCONJ
ajbspi-57894	1	14	pharmaceutical	pharmaceutical	PROPN
ajbspi-57894	1	15	innovation	innovation	NOUN
ajbspi-57894	1	16	(	(	PUNCT
ajbspi-57894	1	17	issn	issn	PROPN
ajbspi-57894	1	18	–	–	PUNCT
ajbspi-57894	1	19	2771	2771	NUM
ajbspi-57894	1	20	-	-	SYM
ajbspi-57894	1	21	2753	2753	NUM
ajbspi-57894	1	22	)	)	PUNCT
ajbspi-57894	1	23	volume	volume	NOUN
ajbspi-57894	1	24	04	04	NUM
ajbspi-57894	1	25	issue	issue	NOUN
ajbspi-57894	1	26	11	11	NUM
ajbspi-57894	1	27	pages	page	NOUN
ajbspi-57894	1	28	:	:	PUNCT
ajbspi-57894	1	29	1	1	NUM
ajbspi-57894	1	30	-	-	SYM
ajbspi-57894	1	31	7	7	NUM
ajbspi-57894	1	32	oclc	oclc	PROPN
ajbspi-57894	1	33	–	–	PUNCT
ajbspi-57894	1	34	1121105677	1121105677	NUM
ajbspi-57894	1	35	publisher	publisher	NOUN
ajbspi-57894	1	36	:	:	PUNCT
ajbspi-57894	1	37	oscar	oscar	NOUN
ajbspi-57894	1	38	publishing	publishing	NOUN
ajbspi-57894	1	39	services	service	NOUN
ajbspi-57894	1	40	servi	servi	PROPN
ajbspi-57894	1	41	abstract	abstract	ADJ
ajbspi-57894	1	42	cefetamet	cefetamet	VERB
ajbspi-57894	1	43	sodium	sodium	NOUN
ajbspi-57894	1	44	,	,	PUNCT
ajbspi-57894	1	45	a	a	DET
ajbspi-57894	1	46	third	third	ADJ
ajbspi-57894	1	47	-	-	PUNCT
ajbspi-57894	1	48	generation	generation	NOUN
ajbspi-57894	1	49	cephalosporin	cephalosporin	NOUN
ajbspi-57894	1	50	antibiotic	antibiotic	ADJ
ajbspi-57894	1	51	,	,	PUNCT
ajbspi-57894	1	52	has	have	AUX
ajbspi-57894	1	53	gained	gain	VERB
ajbspi-57894	1	54	significant	significant	ADJ
ajbspi-57894	1	55	attention	attention	NOUN
ajbspi-57894	1	56	due	due	ADP
ajbspi-57894	1	57	to	to	ADP
ajbspi-57894	1	58	its	its	PRON
ajbspi-57894	1	59	efficacy	efficacy	NOUN
ajbspi-57894	1	60	against	against	ADP
ajbspi-57894	1	61	a	a	DET
ajbspi-57894	1	62	broad	broad	ADJ
ajbspi-57894	1	63	spectrum	spectrum	NOUN
ajbspi-57894	1	64	of	of	ADP
ajbspi-57894	1	65	bacterial	bacterial	ADJ
ajbspi-57894	1	66	infections	infection	NOUN
ajbspi-57894	1	67	.	.	PUNCT
ajbspi-57894	2	1	however	however	ADV
ajbspi-57894	2	2	,	,	PUNCT
ajbspi-57894	2	3	existing	exist	VERB
ajbspi-57894	2	4	synthesis	synthesis	NOUN
ajbspi-57894	2	5	methods	method	NOUN
ajbspi-57894	2	6	often	often	ADV
ajbspi-57894	2	7	present	present	VERB
ajbspi-57894	2	8	challenges	challenge	NOUN
ajbspi-57894	2	9	such	such	ADJ
ajbspi-57894	2	10	as	as	ADP
ajbspi-57894	2	11	low	low	ADJ
ajbspi-57894	2	12	yields	yield	NOUN
ajbspi-57894	2	13	,	,	PUNCT
ajbspi-57894	2	14	complex	complex	ADJ
ajbspi-57894	2	15	procedures	procedure	NOUN
ajbspi-57894	2	16	,	,	PUNCT
ajbspi-57894	2	17	and	and	CCONJ
ajbspi-57894	2	18	environmental	environmental	ADJ
ajbspi-57894	2	19	concerns	concern	NOUN
ajbspi-57894	2	20	.	.	PUNCT
ajbspi-57894	3	1	this	this	DET
ajbspi-57894	3	2	study	study	NOUN
ajbspi-57894	3	3	presents	present	VERB
ajbspi-57894	3	4	a	a	DET
ajbspi-57894	3	5	comprehensive	comprehensive	ADJ
ajbspi-57894	3	6	approach	approach	NOUN
ajbspi-57894	3	7	to	to	PART
ajbspi-57894	3	8	process	process	NOUN
ajbspi-57894	3	9	development	development	NOUN
ajbspi-57894	3	10	aimed	aim	VERB
ajbspi-57894	3	11	at	at	ADP
ajbspi-57894	3	12	optimizing	optimize	VERB
ajbspi-57894	3	13	the	the	DET
ajbspi-57894	3	14	synthesis	synthesis	NOUN
ajbspi-57894	3	15	of	of	ADP
ajbspi-57894	3	16	cefetamet	cefetamet	ADJ
ajbspi-57894	3	17	sodium	sodium	NOUN
ajbspi-57894	3	18	.	.	PUNCT
ajbspi-57894	4	1	we	we	PRON
ajbspi-57894	4	2	explored	explore	VERB
ajbspi-57894	4	3	novel	novel	ADJ
ajbspi-57894	4	4	pathways	pathway	NOUN
ajbspi-57894	4	5	,	,	PUNCT
ajbspi-57894	4	6	employing	employ	VERB
ajbspi-57894	4	7	innovative	innovative	ADJ
ajbspi-57894	4	8	synthetic	synthetic	ADJ
ajbspi-57894	4	9	routes	route	NOUN
ajbspi-57894	4	10	and	and	CCONJ
ajbspi-57894	4	11	green	green	ADJ
ajbspi-57894	4	12	chemistry	chemistry	NOUN
ajbspi-57894	4	13	principles	principle	NOUN
ajbspi-57894	4	14	to	to	PART
ajbspi-57894	4	15	enhance	enhance	VERB
ajbspi-57894	4	16	yield	yield	NOUN
ajbspi-57894	4	17	and	and	CCONJ
ajbspi-57894	4	18	reduce	reduce	VERB
ajbspi-57894	4	19	waste	waste	NOUN
ajbspi-57894	4	20	.	.	PUNCT
ajbspi-57894	5	1	key	key	ADJ
ajbspi-57894	5	2	parameters	parameter	NOUN
ajbspi-57894	5	3	including	include	VERB
ajbspi-57894	5	4	reaction	reaction	NOUN
ajbspi-57894	5	5	conditions	condition	NOUN
ajbspi-57894	5	6	,	,	PUNCT
ajbspi-57894	5	7	catalyst	catalyst	NOUN
ajbspi-57894	5	8	selection	selection	NOUN
ajbspi-57894	5	9	,	,	PUNCT
ajbspi-57894	5	10	and	and	CCONJ
ajbspi-57894	5	11	purification	purification	NOUN
ajbspi-57894	5	12	techniques	technique	NOUN
ajbspi-57894	5	13	were	be	AUX
ajbspi-57894	5	14	systematically	systematically	ADV
ajbspi-57894	5	15	evaluated	evaluate	VERB
ajbspi-57894	5	16	to	to	PART
ajbspi-57894	5	17	establish	establish	VERB
ajbspi-57894	5	18	an	an	DET
ajbspi-57894	5	19	efficient	efficient	ADJ
ajbspi-57894	5	20	and	and	CCONJ
ajbspi-57894	5	21	reproducible	reproducible	ADJ
ajbspi-57894	5	22	process	process	NOUN
ajbspi-57894	5	23	.	.	PUNCT
ajbspi-57894	6	1	the	the	DET
ajbspi-57894	6	2	results	result	NOUN
ajbspi-57894	6	3	demonstrated	demonstrate	VERB
ajbspi-57894	6	4	significant	significant	ADJ
ajbspi-57894	6	5	improvements	improvement	NOUN
ajbspi-57894	6	6	in	in	ADP
ajbspi-57894	6	7	overall	overall	ADJ
ajbspi-57894	6	8	yield	yield	NOUN
ajbspi-57894	6	9	and	and	CCONJ
ajbspi-57894	6	10	purity	purity	NOUN
ajbspi-57894	6	11	of	of	ADP
ajbspi-57894	6	12	the	the	DET
ajbspi-57894	6	13	final	final	ADJ
ajbspi-57894	6	14	product	product	NOUN
ajbspi-57894	6	15	.	.	PUNCT
ajbspi-57894	7	1	additionally	additionally	ADV
ajbspi-57894	7	2	,	,	PUNCT
ajbspi-57894	7	3	the	the	DET
ajbspi-57894	7	4	developed	develop	VERB
ajbspi-57894	7	5	process	process	NOUN
ajbspi-57894	7	6	was	be	AUX
ajbspi-57894	7	7	assessed	assess	VERB
ajbspi-57894	7	8	for	for	ADP
ajbspi-57894	7	9	scalability	scalability	NOUN
ajbspi-57894	7	10	,	,	PUNCT
ajbspi-57894	7	11	feasibility	feasibility	NOUN
ajbspi-57894	7	12	,	,	PUNCT
ajbspi-57894	7	13	and	and	CCONJ
ajbspi-57894	7	14	economic	economic	ADJ
ajbspi-57894	7	15	viability	viability	NOUN
ajbspi-57894	7	16	.	.	PUNCT
ajbspi-57894	8	1	this	this	DET
ajbspi-57894	8	2	research	research	NOUN
ajbspi-57894	8	3	contributes	contribute	VERB
ajbspi-57894	8	4	valuable	valuable	ADJ
ajbspi-57894	8	5	insights	insight	NOUN
ajbspi-57894	8	6	into	into	ADP
ajbspi-57894	8	7	the	the	DET
ajbspi-57894	8	8	synthesis	synthesis	NOUN
ajbspi-57894	8	9	of	of	ADP
ajbspi-57894	8	10	cefetamet	cefetamet	ADJ
ajbspi-57894	8	11	sodium	sodium	NOUN
ajbspi-57894	8	12	,	,	PUNCT
ajbspi-57894	8	13	paving	pave	VERB
ajbspi-57894	8	14	the	the	DET
ajbspi-57894	8	15	way	way	NOUN
ajbspi-57894	8	16	for	for	ADP
ajbspi-57894	8	17	more	more	ADV
ajbspi-57894	8	18	sustainable	sustainable	ADJ
ajbspi-57894	8	19	production	production	NOUN
ajbspi-57894	8	20	practices	practice	NOUN
ajbspi-57894	8	21	in	in	ADP
ajbspi-57894	8	22	the	the	DET
ajbspi-57894	8	23	pharmaceutical	pharmaceutical	ADJ
ajbspi-57894	8	24	industry	industry	NOUN
ajbspi-57894	8	25	.	.	PUNCT
ajbspi-57894	9	1	keywords	keyword	NOUN
ajbspi-57894	9	2	cefetamet	cefetamet	VERB
ajbspi-57894	9	3	sodium	sodium	NOUN
ajbspi-57894	9	4	,	,	PUNCT
ajbspi-57894	9	5	antibiotic	antibiotic	ADJ
ajbspi-57894	9	6	synthesis	synthesis	NOUN
ajbspi-57894	9	7	,	,	PUNCT
ajbspi-57894	9	8	process	process	NOUN
ajbspi-57894	9	9	development	development	NOUN
ajbspi-57894	9	10	,	,	PUNCT
ajbspi-57894	9	11	green	green	ADJ
ajbspi-57894	9	12	chemistry	chemistry	NOUN
ajbspi-57894	9	13	,	,	PUNCT
ajbspi-57894	9	14	synthetic	synthetic	ADJ
ajbspi-57894	9	15	routes	route	NOUN
ajbspi-57894	9	16	,	,	PUNCT
ajbspi-57894	9	17	yield	yield	VERB
ajbspi-57894	9	18	optimization	optimization	NOUN
ajbspi-57894	9	19	,	,	PUNCT
ajbspi-57894	9	20	pharmaceutical	pharmaceutical	NOUN
ajbspi-57894	9	21	manufacturing	manufacturing	NOUN
ajbspi-57894	9	22	.	.	PUNCT
ajbspi-57894	10	1	introduction	introduction	NOUN
ajbspi-57894	10	2	cefetamet	cefetamet	NOUN
ajbspi-57894	10	3	sodium	sodium	NOUN
ajbspi-57894	10	4	,	,	PUNCT
ajbspi-57894	10	5	a	a	DET
ajbspi-57894	10	6	third	third	ADJ
ajbspi-57894	10	7	-	-	PUNCT
ajbspi-57894	10	8	generation	generation	NOUN
ajbspi-57894	10	9	cephalosporin	cephalosporin	NOUN
ajbspi-57894	10	10	antibiotic	antibiotic	ADJ
ajbspi-57894	10	11	,	,	PUNCT
ajbspi-57894	10	12	has	have	AUX
ajbspi-57894	10	13	emerged	emerge	VERB
ajbspi-57894	10	14	as	as	ADP
ajbspi-57894	10	15	a	a	DET
ajbspi-57894	10	16	critical	critical	ADJ
ajbspi-57894	10	17	therapeutic	therapeutic	ADJ
ajbspi-57894	10	18	agent	agent	NOUN
ajbspi-57894	10	19	in	in	ADP
ajbspi-57894	10	20	the	the	DET
ajbspi-57894	10	21	treatment	treatment	NOUN
ajbspi-57894	10	22	of	of	ADP
ajbspi-57894	10	23	various	various	ADJ
ajbspi-57894	10	24	bacterial	bacterial	ADJ
ajbspi-57894	10	25	infections	infection	NOUN
ajbspi-57894	10	26	,	,	PUNCT
ajbspi-57894	10	27	particularly	particularly	ADV
ajbspi-57894	10	28	those	those	PRON
ajbspi-57894	10	29	caused	cause	VERB
ajbspi-57894	10	30	by	by	ADP
ajbspi-57894	10	31	gram	gram	NOUN
ajbspi-57894	10	32	-	-	PUNCT
ajbspi-57894	10	33	negative	negative	ADJ
ajbspi-57894	10	34	organisms	organism	NOUN
ajbspi-57894	10	35	.	.	PUNCT
ajbspi-57894	11	1	research	research	NOUN
ajbspi-57894	11	2	article	article	NOUN
ajbspi-57894	11	3	exploring	explore	VERB
ajbspi-57894	11	4	new	new	ADJ
ajbspi-57894	11	5	pathways	pathway	NOUN
ajbspi-57894	11	6	:	:	PUNCT
ajbspi-57894	11	7	process	process	NOUN
ajbspi-57894	11	8	development	development	NOUN
ajbspi-57894	11	9	for	for	ADP
ajbspi-57894	11	10	cefetamet	cefetamet	ADJ
ajbspi-57894	11	11	sodium	sodium	NOUN
ajbspi-57894	11	12	synthesi	synthesi	NOUN
ajbspi-57894	11	13	submission	submission	NOUN
ajbspi-57894	11	14	date	date	NOUN
ajbspi-57894	11	15	:	:	PUNCT
ajbspi-57894	11	16	october	october	PROPN
ajbspi-57894	11	17	22	22	NUM
ajbspi-57894	11	18	,	,	PUNCT
ajbspi-57894	11	19	2024	2024	NUM
ajbspi-57894	11	20	,	,	PUNCT
ajbspi-57894	11	21	accepted	accept	VERB
ajbspi-57894	11	22	date	date	NOUN
ajbspi-57894	11	23	:	:	PUNCT
ajbspi-57894	11	24	october	october	PROPN
ajbspi-57894	11	25	27	27	NUM
ajbspi-57894	11	26	,	,	PUNCT
ajbspi-57894	11	27	2024	2024	NUM
ajbspi-57894	11	28	,	,	PUNCT
ajbspi-57894	11	29	published	publish	VERB
ajbspi-57894	11	30	date	date	NOUN
ajbspi-57894	11	31	:	:	PUNCT
ajbspi-57894	11	32	november	november	PROPN
ajbspi-57894	11	33	01	01	NUM
ajbspi-57894	11	34	,	,	PUNCT
ajbspi-57894	11	35	2024	2024	NUM
ajbspi-57894	11	36	ritesh	ritesh	PROPN
ajbspi-57894	11	37	kumar	kumar	PROPN
ajbspi-57894	11	38	jat	jat	PROPN
ajbspi-57894	11	39	institute	institute	PROPN
ajbspi-57894	11	40	of	of	ADP
ajbspi-57894	11	41	pharmacy	pharmacy	PROPN
ajbspi-57894	11	42	,	,	PUNCT
ajbspi-57894	11	43	shri	shri	PROPN
ajbspi-57894	11	44	jagdishprasad	jagdishprasad	PROPN
ajbspi-57894	11	45	jhabarmal	jhabarmal	PROPN
ajbspi-57894	11	46	tibrewala	tibrewala	PROPN
ajbspi-57894	11	47	university	university	PROPN
ajbspi-57894	11	48	,	,	PUNCT
ajbspi-57894	11	49	jhunjhunu	jhunjhunu	PROPN
ajbspi-57894	11	50	rajasthan	rajasthan	PROPN
ajbspi-57894	11	51	,	,	PUNCT
ajbspi-57894	11	52	india	india	PROPN
ajbspi-57894	11	53	journal	journal	PROPN
ajbspi-57894	11	54	website	website	NOUN
ajbspi-57894	11	55	:	:	PUNCT
ajbspi-57894	11	56	https://theusajournals	https://theusajournals	PROPN
ajbspi-57894	11	57	.	.	PUNCT
ajbspi-57894	11	58	com	com	NOUN
ajbspi-57894	11	59	/	/	SYM
ajbspi-57894	11	60	index.php	index.php	VERB
ajbspi-57894	11	61	/	/	SYM
ajbspi-57894	11	62	ajbspi	ajbspi	NOUN
ajbspi-57894	11	63	copyright	copyright	NOUN
ajbspi-57894	11	64	:	:	PUNCT
ajbspi-57894	11	65	original	original	ADJ
ajbspi-57894	11	66	content	content	NOUN
ajbspi-57894	11	67	from	from	ADP
ajbspi-57894	11	68	this	this	DET
ajbspi-57894	11	69	work	work	NOUN
ajbspi-57894	11	70	may	may	AUX
ajbspi-57894	11	71	be	be	AUX
ajbspi-57894	11	72	used	use	VERB
ajbspi-57894	11	73	under	under	ADP
ajbspi-57894	11	74	the	the	DET
ajbspi-57894	11	75	terms	term	NOUN
ajbspi-57894	11	76	of	of	ADP
ajbspi-57894	11	77	the	the	DET
ajbspi-57894	11	78	creative	creative	ADJ
ajbspi-57894	11	79	commons	common	NOUN
ajbspi-57894	11	80	attributes	attribute	VERB
ajbspi-57894	11	81	4.0	4.0	NUM
ajbspi-57894	11	82	licence	licence	NOUN
ajbspi-57894	11	83	.	.	PUNCT
ajbspi-57894	12	1	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	PROPN
ajbspi-57894	12	2	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	AUX
ajbspi-57894	12	3	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	VERB
ajbspi-57894	12	4	https://theusajournals.com/	https://theusajournals.com/	ADJ
ajbspi-57894	12	5	https://theusajournals.com/index.php/ajbspi	https://theusajournals.com/index.php/ajbspi	NOUN
ajbspi-57894	12	6	https://theusajournals.com/index.php/ajbspi	https://theusajournals.com/index.php/ajbspi	NOUN
ajbspi-57894	12	7	https://theusajournals.com/index.php/ajbspi	https://theusajournals.com/index.php/ajbspi	NOUN
ajbspi-57894	12	8	https://theusajournals.com/index.php/ajbspi	https://theusajournals.com/index.php/ajbspi	NOUN
ajbspi-57894	12	9	volume	volume	NOUN
ajbspi-57894	12	10	04	04	NUM
ajbspi-57894	12	11	issue	issue	NOUN
ajbspi-57894	12	12	11	11	NUM
ajbspi-57894	12	13	-	-	SYM
ajbspi-57894	12	14	2024	2024	NUM
ajbspi-57894	12	15	2	2	NUM
ajbspi-57894	12	16	american	american	ADJ
ajbspi-57894	12	17	journal	journal	NOUN
ajbspi-57894	12	18	of	of	ADP
ajbspi-57894	12	19	biomedical	biomedical	PROPN
ajbspi-57894	12	20	science	science	PROPN
ajbspi-57894	12	21	&	&	CCONJ
ajbspi-57894	12	22	pharmaceutical	pharmaceutical	PROPN
ajbspi-57894	12	23	innovation	innovation	NOUN
ajbspi-57894	12	24	(	(	PUNCT
ajbspi-57894	12	25	issn	issn	PROPN
ajbspi-57894	12	26	–	–	PUNCT
ajbspi-57894	12	27	2771	2771	NUM
ajbspi-57894	12	28	-	-	SYM
ajbspi-57894	12	29	2753	2753	NUM
ajbspi-57894	12	30	)	)	PUNCT
ajbspi-57894	12	31	volume	volume	NOUN
ajbspi-57894	12	32	04	04	NUM
ajbspi-57894	12	33	issue	issue	NOUN
ajbspi-57894	12	34	11	11	NUM
ajbspi-57894	12	35	pages	page	NOUN
ajbspi-57894	12	36	:	:	PUNCT
ajbspi-57894	12	37	1	1	NUM
ajbspi-57894	12	38	-	-	SYM
ajbspi-57894	12	39	7	7	NUM
ajbspi-57894	12	40	oclc	oclc	PROPN
ajbspi-57894	12	41	–	–	PUNCT
ajbspi-57894	12	42	1121105677	1121105677	NUM
ajbspi-57894	12	43	publisher	publisher	NOUN
ajbspi-57894	12	44	:	:	PUNCT
ajbspi-57894	12	45	oscar	oscar	NOUN
ajbspi-57894	12	46	publishing	publishing	NOUN
ajbspi-57894	12	47	services	service	NOUN
ajbspi-57894	12	48	servi	servi	VERB
ajbspi-57894	12	49	its	its	PRON
ajbspi-57894	12	50	broad	broad	ADJ
ajbspi-57894	12	51	-	-	PUNCT
ajbspi-57894	12	52	spectrum	spectrum	NOUN
ajbspi-57894	12	53	activity	activity	NOUN
ajbspi-57894	12	54	and	and	CCONJ
ajbspi-57894	12	55	favorable	favorable	ADJ
ajbspi-57894	12	56	pharmacokinetic	pharmacokinetic	ADJ
ajbspi-57894	12	57	properties	property	NOUN
ajbspi-57894	12	58	make	make	VERB
ajbspi-57894	12	59	it	it	PRON
ajbspi-57894	12	60	a	a	DET
ajbspi-57894	12	61	valuable	valuable	ADJ
ajbspi-57894	12	62	option	option	NOUN
ajbspi-57894	12	63	in	in	ADP
ajbspi-57894	12	64	the	the	DET
ajbspi-57894	12	65	arsenal	arsenal	NOUN
ajbspi-57894	12	66	of	of	ADP
ajbspi-57894	12	67	antibiotics	antibiotic	NOUN
ajbspi-57894	12	68	used	use	VERB
ajbspi-57894	12	69	in	in	ADP
ajbspi-57894	12	70	clinical	clinical	ADJ
ajbspi-57894	12	71	settings	setting	NOUN
ajbspi-57894	12	72	.	.	PUNCT
ajbspi-57894	13	1	however	however	ADV
ajbspi-57894	13	2	,	,	PUNCT
ajbspi-57894	13	3	the	the	DET
ajbspi-57894	13	4	growing	grow	VERB
ajbspi-57894	13	5	prevalence	prevalence	NOUN
ajbspi-57894	13	6	of	of	ADP
ajbspi-57894	13	7	antibiotic	antibiotic	ADJ
ajbspi-57894	13	8	resistance	resistance	NOUN
ajbspi-57894	13	9	has	have	AUX
ajbspi-57894	13	10	necessitated	necessitate	VERB
ajbspi-57894	13	11	the	the	DET
ajbspi-57894	13	12	continuous	continuous	ADJ
ajbspi-57894	13	13	development	development	NOUN
ajbspi-57894	13	14	and	and	CCONJ
ajbspi-57894	13	15	optimization	optimization	NOUN
ajbspi-57894	13	16	of	of	ADP
ajbspi-57894	13	17	new	new	ADJ
ajbspi-57894	13	18	and	and	CCONJ
ajbspi-57894	13	19	existing	exist	VERB
ajbspi-57894	13	20	antimicrobial	antimicrobial	ADJ
ajbspi-57894	13	21	agents	agent	NOUN
ajbspi-57894	13	22	,	,	PUNCT
ajbspi-57894	13	23	including	include	VERB
ajbspi-57894	13	24	cefetamet	cefetamet	NOUN
ajbspi-57894	13	25	sodium	sodium	NOUN
ajbspi-57894	13	26	.	.	PUNCT
ajbspi-57894	14	1	traditionally	traditionally	ADV
ajbspi-57894	14	2	,	,	PUNCT
ajbspi-57894	14	3	the	the	DET
ajbspi-57894	14	4	synthesis	synthesis	NOUN
ajbspi-57894	14	5	of	of	ADP
ajbspi-57894	14	6	cefetamet	cefetamet	ADJ
ajbspi-57894	14	7	sodium	sodium	NOUN
ajbspi-57894	14	8	has	have	AUX
ajbspi-57894	14	9	involved	involve	VERB
ajbspi-57894	14	10	complex	complex	ADJ
ajbspi-57894	14	11	multi	multi	ADJ
ajbspi-57894	14	12	-	-	ADJ
ajbspi-57894	14	13	step	step	ADJ
ajbspi-57894	14	14	processes	process	NOUN
ajbspi-57894	14	15	that	that	PRON
ajbspi-57894	14	16	often	often	ADV
ajbspi-57894	14	17	lead	lead	VERB
ajbspi-57894	14	18	to	to	ADP
ajbspi-57894	14	19	low	low	ADJ
ajbspi-57894	14	20	yields	yield	NOUN
ajbspi-57894	14	21	and	and	CCONJ
ajbspi-57894	14	22	the	the	DET
ajbspi-57894	14	23	generation	generation	NOUN
ajbspi-57894	14	24	of	of	ADP
ajbspi-57894	14	25	hazardous	hazardous	ADJ
ajbspi-57894	14	26	byproducts	byproduct	NOUN
ajbspi-57894	14	27	.	.	PUNCT
ajbspi-57894	15	1	these	these	DET
ajbspi-57894	15	2	challenges	challenge	NOUN
ajbspi-57894	15	3	not	not	PART
ajbspi-57894	15	4	only	only	ADV
ajbspi-57894	15	5	impact	impact	VERB
ajbspi-57894	15	6	the	the	DET
ajbspi-57894	15	7	efficiency	efficiency	NOUN
ajbspi-57894	15	8	of	of	ADP
ajbspi-57894	15	9	production	production	NOUN
ajbspi-57894	15	10	but	but	CCONJ
ajbspi-57894	15	11	also	also	ADV
ajbspi-57894	15	12	raise	raise	VERB
ajbspi-57894	15	13	environmental	environmental	ADJ
ajbspi-57894	15	14	concerns	concern	NOUN
ajbspi-57894	15	15	related	relate	VERB
ajbspi-57894	15	16	to	to	ADP
ajbspi-57894	15	17	the	the	DET
ajbspi-57894	15	18	pharmaceutical	pharmaceutical	ADJ
ajbspi-57894	15	19	manufacturing	manufacturing	NOUN
ajbspi-57894	15	20	sector	sector	NOUN
ajbspi-57894	15	21	.	.	PUNCT
ajbspi-57894	16	1	as	as	ADP
ajbspi-57894	16	2	the	the	DET
ajbspi-57894	16	3	demand	demand	NOUN
ajbspi-57894	16	4	for	for	ADP
ajbspi-57894	16	5	high	high	ADJ
ajbspi-57894	16	6	-	-	PUNCT
ajbspi-57894	16	7	quality	quality	NOUN
ajbspi-57894	16	8	pharmaceuticals	pharmaceutical	NOUN
ajbspi-57894	16	9	increases	increase	NOUN
ajbspi-57894	16	10	,	,	PUNCT
ajbspi-57894	16	11	there	there	PRON
ajbspi-57894	16	12	is	be	VERB
ajbspi-57894	16	13	a	a	DET
ajbspi-57894	16	14	pressing	press	VERB
ajbspi-57894	16	15	need	need	NOUN
ajbspi-57894	16	16	for	for	ADP
ajbspi-57894	16	17	innovative	innovative	ADJ
ajbspi-57894	16	18	approaches	approach	NOUN
ajbspi-57894	16	19	to	to	PART
ajbspi-57894	16	20	streamline	streamline	VERB
ajbspi-57894	16	21	the	the	DET
ajbspi-57894	16	22	synthesis	synthesis	NOUN
ajbspi-57894	16	23	processes	process	NOUN
ajbspi-57894	16	24	,	,	PUNCT
ajbspi-57894	16	25	enhance	enhance	VERB
ajbspi-57894	16	26	product	product	NOUN
ajbspi-57894	16	27	yield	yield	NOUN
ajbspi-57894	16	28	,	,	PUNCT
ajbspi-57894	16	29	and	and	CCONJ
ajbspi-57894	16	30	minimize	minimize	VERB
ajbspi-57894	16	31	waste	waste	NOUN
ajbspi-57894	16	32	.	.	PUNCT
ajbspi-57894	17	1	recent	recent	ADJ
ajbspi-57894	17	2	advancements	advancement	NOUN
ajbspi-57894	17	3	in	in	ADP
ajbspi-57894	17	4	synthetic	synthetic	ADJ
ajbspi-57894	17	5	organic	organic	ADJ
ajbspi-57894	17	6	chemistry	chemistry	NOUN
ajbspi-57894	17	7	and	and	CCONJ
ajbspi-57894	17	8	green	green	ADJ
ajbspi-57894	17	9	chemistry	chemistry	NOUN
ajbspi-57894	17	10	principles	principle	NOUN
ajbspi-57894	17	11	present	present	VERB
ajbspi-57894	17	12	new	new	ADJ
ajbspi-57894	17	13	opportunities	opportunity	NOUN
ajbspi-57894	17	14	for	for	ADP
ajbspi-57894	17	15	the	the	DET
ajbspi-57894	17	16	development	development	NOUN
ajbspi-57894	17	17	of	of	ADP
ajbspi-57894	17	18	more	more	ADV
ajbspi-57894	17	19	efficient	efficient	ADJ
ajbspi-57894	17	20	and	and	CCONJ
ajbspi-57894	17	21	sustainable	sustainable	ADJ
ajbspi-57894	17	22	synthesis	synthesis	NOUN
ajbspi-57894	17	23	routes	route	NOUN
ajbspi-57894	17	24	.	.	PUNCT
ajbspi-57894	18	1	by	by	ADP
ajbspi-57894	18	2	leveraging	leverage	VERB
ajbspi-57894	18	3	these	these	DET
ajbspi-57894	18	4	advancements	advancement	NOUN
ajbspi-57894	18	5	,	,	PUNCT
ajbspi-57894	18	6	researchers	researcher	NOUN
ajbspi-57894	18	7	can	can	AUX
ajbspi-57894	18	8	explore	explore	VERB
ajbspi-57894	18	9	alternative	alternative	ADJ
ajbspi-57894	18	10	pathways	pathway	NOUN
ajbspi-57894	18	11	that	that	PRON
ajbspi-57894	18	12	may	may	AUX
ajbspi-57894	18	13	lead	lead	VERB
ajbspi-57894	18	14	to	to	ADP
ajbspi-57894	18	15	significant	significant	ADJ
ajbspi-57894	18	16	improvements	improvement	NOUN
ajbspi-57894	18	17	in	in	ADP
ajbspi-57894	18	18	the	the	DET
ajbspi-57894	18	19	synthesis	synthesis	NOUN
ajbspi-57894	18	20	of	of	ADP
ajbspi-57894	18	21	cefetamet	cefetamet	ADJ
ajbspi-57894	18	22	sodium	sodium	NOUN
ajbspi-57894	18	23	.	.	PUNCT
ajbspi-57894	19	1	this	this	DET
ajbspi-57894	19	2	study	study	NOUN
ajbspi-57894	19	3	aims	aim	VERB
ajbspi-57894	19	4	to	to	PART
ajbspi-57894	19	5	identify	identify	VERB
ajbspi-57894	19	6	and	and	CCONJ
ajbspi-57894	19	7	evaluate	evaluate	VERB
ajbspi-57894	19	8	novel	novel	ADJ
ajbspi-57894	19	9	synthetic	synthetic	ADJ
ajbspi-57894	19	10	routes	route	NOUN
ajbspi-57894	19	11	,	,	PUNCT
ajbspi-57894	19	12	focusing	focus	VERB
ajbspi-57894	19	13	on	on	ADP
ajbspi-57894	19	14	key	key	ADJ
ajbspi-57894	19	15	parameters	parameter	NOUN
ajbspi-57894	19	16	such	such	ADJ
ajbspi-57894	19	17	as	as	ADP
ajbspi-57894	19	18	reaction	reaction	NOUN
ajbspi-57894	19	19	conditions	condition	NOUN
ajbspi-57894	19	20	,	,	PUNCT
ajbspi-57894	19	21	catalyst	catalyst	NOUN
ajbspi-57894	19	22	selection	selection	NOUN
ajbspi-57894	19	23	,	,	PUNCT
ajbspi-57894	19	24	and	and	CCONJ
ajbspi-57894	19	25	purification	purification	NOUN
ajbspi-57894	19	26	techniques	technique	NOUN
ajbspi-57894	19	27	.	.	PUNCT
ajbspi-57894	20	1	furthermore	furthermore	ADV
ajbspi-57894	20	2	,	,	PUNCT
ajbspi-57894	20	3	the	the	DET
ajbspi-57894	20	4	study	study	NOUN
ajbspi-57894	20	5	will	will	AUX
ajbspi-57894	20	6	assess	assess	VERB
ajbspi-57894	20	7	the	the	DET
ajbspi-57894	20	8	scalability	scalability	NOUN
ajbspi-57894	20	9	and	and	CCONJ
ajbspi-57894	20	10	economic	economic	ADJ
ajbspi-57894	20	11	viability	viability	NOUN
ajbspi-57894	20	12	of	of	ADP
ajbspi-57894	20	13	the	the	DET
ajbspi-57894	20	14	newly	newly	ADV
ajbspi-57894	20	15	developed	develop	VERB
ajbspi-57894	20	16	processes	process	NOUN
ajbspi-57894	20	17	to	to	PART
ajbspi-57894	20	18	ensure	ensure	VERB
ajbspi-57894	20	19	their	their	PRON
ajbspi-57894	20	20	practical	practical	ADJ
ajbspi-57894	20	21	application	application	NOUN
ajbspi-57894	20	22	in	in	ADP
ajbspi-57894	20	23	a	a	DET
ajbspi-57894	20	24	commercial	commercial	ADJ
ajbspi-57894	20	25	setting	setting	NOUN
ajbspi-57894	20	26	.	.	PUNCT
ajbspi-57894	21	1	the	the	DET
ajbspi-57894	21	2	insights	insight	NOUN
ajbspi-57894	21	3	gained	gain	VERB
ajbspi-57894	21	4	from	from	ADP
ajbspi-57894	21	5	this	this	DET
ajbspi-57894	21	6	research	research	NOUN
ajbspi-57894	21	7	not	not	PART
ajbspi-57894	21	8	only	only	ADV
ajbspi-57894	21	9	aim	aim	VERB
ajbspi-57894	21	10	to	to	PART
ajbspi-57894	21	11	optimize	optimize	VERB
ajbspi-57894	21	12	the	the	DET
ajbspi-57894	21	13	synthesis	synthesis	NOUN
ajbspi-57894	21	14	of	of	ADP
ajbspi-57894	21	15	cefetamet	cefetamet	ADJ
ajbspi-57894	21	16	sodium	sodium	NOUN
ajbspi-57894	21	17	but	but	CCONJ
ajbspi-57894	21	18	also	also	ADV
ajbspi-57894	21	19	contribute	contribute	VERB
ajbspi-57894	21	20	to	to	ADP
ajbspi-57894	21	21	the	the	DET
ajbspi-57894	21	22	broader	broad	ADJ
ajbspi-57894	21	23	field	field	NOUN
ajbspi-57894	21	24	of	of	ADP
ajbspi-57894	21	25	pharmaceutical	pharmaceutical	NOUN
ajbspi-57894	21	26	manufacturing	manufacturing	NOUN
ajbspi-57894	21	27	by	by	ADP
ajbspi-57894	21	28	promoting	promote	VERB
ajbspi-57894	21	29	sustainable	sustainable	ADJ
ajbspi-57894	21	30	practices	practice	NOUN
ajbspi-57894	21	31	.	.	PUNCT
ajbspi-57894	22	1	in	in	ADP
ajbspi-57894	22	2	summary	summary	NOUN
ajbspi-57894	22	3	,	,	PUNCT
ajbspi-57894	22	4	this	this	DET
ajbspi-57894	22	5	investigation	investigation	NOUN
ajbspi-57894	22	6	seeks	seek	VERB
ajbspi-57894	22	7	to	to	PART
ajbspi-57894	22	8	address	address	VERB
ajbspi-57894	22	9	the	the	DET
ajbspi-57894	22	10	existing	exist	VERB
ajbspi-57894	22	11	challenges	challenge	NOUN
ajbspi-57894	22	12	in	in	ADP
ajbspi-57894	22	13	the	the	DET
ajbspi-57894	22	14	synthesis	synthesis	NOUN
ajbspi-57894	22	15	of	of	ADP
ajbspi-57894	22	16	cefetamet	cefetamet	ADJ
ajbspi-57894	22	17	sodium	sodium	NOUN
ajbspi-57894	22	18	by	by	ADP
ajbspi-57894	22	19	exploring	explore	VERB
ajbspi-57894	22	20	new	new	ADJ
ajbspi-57894	22	21	pathways	pathway	NOUN
ajbspi-57894	22	22	that	that	PRON
ajbspi-57894	22	23	enhance	enhance	VERB
ajbspi-57894	22	24	efficiency	efficiency	NOUN
ajbspi-57894	22	25	,	,	PUNCT
ajbspi-57894	22	26	yield	yield	NOUN
ajbspi-57894	22	27	,	,	PUNCT
ajbspi-57894	22	28	and	and	CCONJ
ajbspi-57894	22	29	environmental	environmental	ADJ
ajbspi-57894	22	30	sustainability	sustainability	NOUN
ajbspi-57894	22	31	.	.	PUNCT
ajbspi-57894	23	1	the	the	DET
ajbspi-57894	23	2	findings	finding	NOUN
ajbspi-57894	23	3	will	will	AUX
ajbspi-57894	23	4	provide	provide	VERB
ajbspi-57894	23	5	valuable	valuable	ADJ
ajbspi-57894	23	6	contributions	contribution	NOUN
ajbspi-57894	23	7	to	to	ADP
ajbspi-57894	23	8	the	the	DET
ajbspi-57894	23	9	ongoing	ongoing	ADJ
ajbspi-57894	23	10	efforts	effort	NOUN
ajbspi-57894	23	11	in	in	ADP
ajbspi-57894	23	12	antibiotic	antibiotic	ADJ
ajbspi-57894	23	13	development	development	NOUN
ajbspi-57894	23	14	and	and	CCONJ
ajbspi-57894	23	15	production	production	NOUN
ajbspi-57894	23	16	,	,	PUNCT
ajbspi-57894	23	17	ultimately	ultimately	ADV
ajbspi-57894	23	18	supporting	support	VERB
ajbspi-57894	23	19	public	public	ADJ
ajbspi-57894	23	20	health	health	NOUN
ajbspi-57894	23	21	initiatives	initiative	NOUN
ajbspi-57894	23	22	in	in	ADP
ajbspi-57894	23	23	combating	combat	VERB
ajbspi-57894	23	24	antibiotic	antibiotic	ADJ
ajbspi-57894	23	25	-	-	PUNCT
ajbspi-57894	23	26	resistant	resistant	ADJ
ajbspi-57894	23	27	infections	infection	NOUN
ajbspi-57894	23	28	.	.	PUNCT
ajbspi-57894	24	1	method	method	VERB
ajbspi-57894	24	2	this	this	DET
ajbspi-57894	24	3	section	section	NOUN
ajbspi-57894	24	4	provides	provide	VERB
ajbspi-57894	24	5	a	a	DET
ajbspi-57894	24	6	comprehensive	comprehensive	ADJ
ajbspi-57894	24	7	overview	overview	NOUN
ajbspi-57894	24	8	of	of	ADP
ajbspi-57894	24	9	the	the	DET
ajbspi-57894	24	10	process	process	NOUN
ajbspi-57894	24	11	developed	develop	VERB
ajbspi-57894	24	12	for	for	ADP
ajbspi-57894	24	13	the	the	DET
ajbspi-57894	24	14	synthesis	synthesis	NOUN
ajbspi-57894	24	15	of	of	ADP
ajbspi-57894	24	16	cefetamet	cefetamet	ADJ
ajbspi-57894	24	17	sodium	sodium	NOUN
ajbspi-57894	24	18	,	,	PUNCT
ajbspi-57894	24	19	detailing	detail	VERB
ajbspi-57894	24	20	the	the	DET
ajbspi-57894	24	21	key	key	ADJ
ajbspi-57894	24	22	steps	step	NOUN
ajbspi-57894	24	23	involved	involve	VERB
ajbspi-57894	24	24	from	from	ADP
ajbspi-57894	24	25	the	the	DET
ajbspi-57894	24	26	initial	initial	ADJ
ajbspi-57894	24	27	reaction	reaction	NOUN
ajbspi-57894	24	28	design	design	NOUN
ajbspi-57894	24	29	to	to	ADP
ajbspi-57894	24	30	the	the	DET
ajbspi-57894	24	31	final	final	ADJ
ajbspi-57894	24	32	purification	purification	NOUN
ajbspi-57894	24	33	and	and	CCONJ
ajbspi-57894	24	34	characterization	characterization	NOUN
ajbspi-57894	24	35	of	of	ADP
ajbspi-57894	24	36	the	the	DET
ajbspi-57894	24	37	product	product	NOUN
ajbspi-57894	24	38	.	.	PUNCT
ajbspi-57894	25	1	the	the	DET
ajbspi-57894	25	2	process	process	NOUN
ajbspi-57894	25	3	emphasizes	emphasize	VERB
ajbspi-57894	25	4	innovative	innovative	ADJ
ajbspi-57894	25	5	pathways	pathway	NOUN
ajbspi-57894	25	6	aimed	aim	VERB
ajbspi-57894	25	7	at	at	ADP
ajbspi-57894	25	8	improving	improve	VERB
ajbspi-57894	25	9	yield	yield	NOUN
ajbspi-57894	25	10	,	,	PUNCT
ajbspi-57894	25	11	efficiency	efficiency	NOUN
ajbspi-57894	25	12	,	,	PUNCT
ajbspi-57894	25	13	and	and	CCONJ
ajbspi-57894	25	14	environmental	environmental	ADJ
ajbspi-57894	25	15	sustainability	sustainability	NOUN
ajbspi-57894	25	16	.	.	PUNCT
ajbspi-57894	26	1	overview	overview	NOUN
ajbspi-57894	26	2	of	of	ADP
ajbspi-57894	26	3	synthetic	synthetic	ADJ
ajbspi-57894	26	4	pathways	pathway	NOUN
ajbspi-57894	26	5	the	the	DET
ajbspi-57894	26	6	synthesis	synthesis	NOUN
ajbspi-57894	26	7	of	of	ADP
ajbspi-57894	26	8	cefetamet	cefetamet	ADJ
ajbspi-57894	26	9	sodium	sodium	NOUN
ajbspi-57894	26	10	was	be	AUX
ajbspi-57894	26	11	approached	approach	VERB
ajbspi-57894	26	12	through	through	ADP
ajbspi-57894	26	13	the	the	DET
ajbspi-57894	26	14	development	development	NOUN
ajbspi-57894	26	15	of	of	ADP
ajbspi-57894	26	16	multiple	multiple	ADJ
ajbspi-57894	26	17	synthetic	synthetic	ADJ
ajbspi-57894	26	18	pathways	pathway	NOUN
ajbspi-57894	26	19	.	.	PUNCT
ajbspi-57894	27	1	each	each	DET
ajbspi-57894	27	2	pathway	pathway	NOUN
ajbspi-57894	27	3	was	be	AUX
ajbspi-57894	27	4	designed	design	VERB
ajbspi-57894	27	5	to	to	PART
ajbspi-57894	27	6	streamline	streamline	VERB
ajbspi-57894	27	7	the	the	DET
ajbspi-57894	27	8	reaction	reaction	NOUN
ajbspi-57894	27	9	process	process	NOUN
ajbspi-57894	27	10	while	while	SCONJ
ajbspi-57894	27	11	minimizing	minimize	VERB
ajbspi-57894	27	12	waste	waste	NOUN
ajbspi-57894	27	13	and	and	CCONJ
ajbspi-57894	27	14	enhancing	enhance	VERB
ajbspi-57894	27	15	overall	overall	ADJ
ajbspi-57894	27	16	yield	yield	NOUN
ajbspi-57894	27	17	.	.	PUNCT
ajbspi-57894	28	1	the	the	DET
ajbspi-57894	28	2	two	two	NUM
ajbspi-57894	28	3	primary	primary	ADJ
ajbspi-57894	28	4	synthetic	synthetic	NOUN
ajbspi-57894	28	5	routes	route	NOUN
ajbspi-57894	28	6	explored	explore	VERB
ajbspi-57894	28	7	are	be	AUX
ajbspi-57894	28	8	outlined	outline	VERB
ajbspi-57894	28	9	below	below	ADV
ajbspi-57894	28	10	:	:	PUNCT
ajbspi-57894	28	11	route	route	VERB
ajbspi-57894	28	12	a	a	DET
ajbspi-57894	28	13	:	:	PUNCT
ajbspi-57894	28	14	direct	direct	ADJ
ajbspi-57894	28	15	acylation	acylation	NOUN
ajbspi-57894	28	16	method	method	NOUN
ajbspi-57894	28	17	this	this	DET
ajbspi-57894	28	18	route	route	NOUN
ajbspi-57894	28	19	involves	involve	VERB
ajbspi-57894	28	20	a	a	DET
ajbspi-57894	28	21	direct	direct	ADJ
ajbspi-57894	28	22	acylation	acylation	NOUN
ajbspi-57894	28	23	reaction	reaction	NOUN
ajbspi-57894	28	24	between	between	ADP
ajbspi-57894	28	25	a	a	DET
ajbspi-57894	28	26	suitable	suitable	ADJ
ajbspi-57894	28	27	7aminocephalosporanic	7aminocephalosporanic	ADJ
ajbspi-57894	28	28	acid	acid	NOUN
ajbspi-57894	28	29	(	(	PUNCT
ajbspi-57894	28	30	7	7	NUM
ajbspi-57894	28	31	-	-	PUNCT
ajbspi-57894	28	32	aca	aca	NOUN
ajbspi-57894	28	33	)	)	PUNCT
ajbspi-57894	28	34	derivative	derivative	NOUN
ajbspi-57894	28	35	and	and	CCONJ
ajbspi-57894	28	36	an	an	DET
ajbspi-57894	28	37	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	NOUN
ajbspi-57894	28	38	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	AUX
ajbspi-57894	28	39	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	ADJ
ajbspi-57894	28	40	volume	volume	NOUN
ajbspi-57894	28	41	04	04	NUM
ajbspi-57894	28	42	issue	issue	NOUN
ajbspi-57894	28	43	11	11	NUM
ajbspi-57894	28	44	-	-	SYM
ajbspi-57894	28	45	2024	2024	NUM
ajbspi-57894	28	46	3	3	NUM
ajbspi-57894	28	47	american	american	ADJ
ajbspi-57894	28	48	journal	journal	PROPN
ajbspi-57894	28	49	of	of	ADP
ajbspi-57894	28	50	biomedical	biomedical	PROPN
ajbspi-57894	28	51	science	science	PROPN
ajbspi-57894	28	52	&	&	CCONJ
ajbspi-57894	28	53	pharmaceutical	pharmaceutical	PROPN
ajbspi-57894	28	54	innovation	innovation	NOUN
ajbspi-57894	28	55	(	(	PUNCT
ajbspi-57894	28	56	issn	issn	PROPN
ajbspi-57894	28	57	–	–	PUNCT
ajbspi-57894	28	58	2771	2771	NUM
ajbspi-57894	28	59	-	-	SYM
ajbspi-57894	28	60	2753	2753	NUM
ajbspi-57894	28	61	)	)	PUNCT
ajbspi-57894	28	62	volume	volume	NOUN
ajbspi-57894	28	63	04	04	NUM
ajbspi-57894	29	1	issue	issue	NOUN
ajbspi-57894	29	2	11	11	NUM
ajbspi-57894	29	3	pages	page	NOUN
ajbspi-57894	29	4	:	:	PUNCT
ajbspi-57894	29	5	1	1	NUM
ajbspi-57894	29	6	-	-	SYM
ajbspi-57894	29	7	7	7	NUM
ajbspi-57894	29	8	oclc	oclc	PROPN
ajbspi-57894	29	9	–	–	PUNCT
ajbspi-57894	29	10	1121105677	1121105677	NUM
ajbspi-57894	29	11	publisher	publisher	NOUN
ajbspi-57894	29	12	:	:	PUNCT
ajbspi-57894	29	13	oscar	oscar	NOUN
ajbspi-57894	29	14	publishing	publishing	NOUN
ajbspi-57894	29	15	services	service	NOUN
ajbspi-57894	29	16	servi	servi	VERB
ajbspi-57894	29	17	appropriate	appropriate	ADJ
ajbspi-57894	29	18	acyl	acyl	NOUN
ajbspi-57894	29	19	chloride	chloride	NOUN
ajbspi-57894	29	20	.	.	PUNCT
ajbspi-57894	30	1	this	this	DET
ajbspi-57894	30	2	method	method	NOUN
ajbspi-57894	30	3	was	be	AUX
ajbspi-57894	30	4	chosen	choose	VERB
ajbspi-57894	30	5	for	for	ADP
ajbspi-57894	30	6	its	its	PRON
ajbspi-57894	30	7	potential	potential	NOUN
ajbspi-57894	30	8	to	to	PART
ajbspi-57894	30	9	simplify	simplify	VERB
ajbspi-57894	30	10	the	the	DET
ajbspi-57894	30	11	synthesis	synthesis	NOUN
ajbspi-57894	30	12	by	by	ADP
ajbspi-57894	30	13	reducing	reduce	VERB
ajbspi-57894	30	14	the	the	DET
ajbspi-57894	30	15	number	number	NOUN
ajbspi-57894	30	16	of	of	ADP
ajbspi-57894	30	17	reaction	reaction	NOUN
ajbspi-57894	30	18	steps	step	NOUN
ajbspi-57894	30	19	.	.	PUNCT
ajbspi-57894	31	1	route	route	NOUN
ajbspi-57894	31	2	b	b	NOUN
ajbspi-57894	31	3	:	:	PUNCT
ajbspi-57894	31	4	intermediary	intermediary	ADJ
ajbspi-57894	31	5	cyclization	cyclization	NOUN
ajbspi-57894	31	6	method	method	NOUN
ajbspi-57894	31	7	in	in	ADP
ajbspi-57894	31	8	this	this	DET
ajbspi-57894	31	9	method	method	NOUN
ajbspi-57894	31	10	,	,	PUNCT
ajbspi-57894	31	11	the	the	DET
ajbspi-57894	31	12	synthesis	synthesis	NOUN
ajbspi-57894	31	13	begins	begin	VERB
ajbspi-57894	31	14	with	with	ADP
ajbspi-57894	31	15	an	an	DET
ajbspi-57894	31	16	acylation	acylation	NOUN
ajbspi-57894	31	17	of	of	ADP
ajbspi-57894	31	18	7aca	7aca	PROPN
ajbspi-57894	31	19	followed	follow	VERB
ajbspi-57894	31	20	by	by	ADP
ajbspi-57894	31	21	a	a	DET
ajbspi-57894	31	22	cyclization	cyclization	NOUN
ajbspi-57894	31	23	step	step	NOUN
ajbspi-57894	31	24	to	to	PART
ajbspi-57894	31	25	form	form	VERB
ajbspi-57894	31	26	the	the	DET
ajbspi-57894	31	27	penam	penam	NOUN
ajbspi-57894	31	28	structure	structure	NOUN
ajbspi-57894	31	29	.	.	PUNCT
ajbspi-57894	32	1	this	this	DET
ajbspi-57894	32	2	route	route	NOUN
ajbspi-57894	32	3	was	be	AUX
ajbspi-57894	32	4	considered	consider	VERB
ajbspi-57894	32	5	for	for	ADP
ajbspi-57894	32	6	its	its	PRON
ajbspi-57894	32	7	ability	ability	NOUN
ajbspi-57894	32	8	to	to	PART
ajbspi-57894	32	9	create	create	VERB
ajbspi-57894	32	10	specific	specific	ADJ
ajbspi-57894	32	11	structural	structural	ADJ
ajbspi-57894	32	12	modifications	modification	NOUN
ajbspi-57894	32	13	that	that	PRON
ajbspi-57894	32	14	could	could	AUX
ajbspi-57894	32	15	enhance	enhance	VERB
ajbspi-57894	32	16	the	the	DET
ajbspi-57894	32	17	antibacterial	antibacterial	ADJ
ajbspi-57894	32	18	properties	property	NOUN
ajbspi-57894	32	19	of	of	ADP
ajbspi-57894	32	20	the	the	DET
ajbspi-57894	32	21	final	final	ADJ
ajbspi-57894	32	22	product	product	NOUN
ajbspi-57894	32	23	.	.	PUNCT
ajbspi-57894	33	1	reagents	reagent	NOUN
ajbspi-57894	33	2	and	and	CCONJ
ajbspi-57894	33	3	conditions	condition	NOUN
ajbspi-57894	33	4	for	for	ADP
ajbspi-57894	33	5	both	both	CCONJ
ajbspi-57894	33	6	synthetic	synthetic	ADJ
ajbspi-57894	33	7	routes	route	NOUN
ajbspi-57894	33	8	,	,	PUNCT
ajbspi-57894	33	9	careful	careful	ADJ
ajbspi-57894	33	10	selection	selection	NOUN
ajbspi-57894	33	11	of	of	ADP
ajbspi-57894	33	12	reagents	reagent	NOUN
ajbspi-57894	33	13	and	and	CCONJ
ajbspi-57894	33	14	optimization	optimization	NOUN
ajbspi-57894	33	15	of	of	ADP
ajbspi-57894	33	16	reaction	reaction	NOUN
ajbspi-57894	33	17	conditions	condition	NOUN
ajbspi-57894	33	18	were	be	AUX
ajbspi-57894	33	19	critical	critical	ADJ
ajbspi-57894	33	20	to	to	ADP
ajbspi-57894	33	21	achieving	achieve	VERB
ajbspi-57894	33	22	high	high	ADJ
ajbspi-57894	33	23	yields	yield	NOUN
ajbspi-57894	33	24	and	and	CCONJ
ajbspi-57894	33	25	purity	purity	NOUN
ajbspi-57894	33	26	.	.	PUNCT
ajbspi-57894	34	1	the	the	DET
ajbspi-57894	34	2	following	follow	VERB
ajbspi-57894	34	3	reagents	reagent	NOUN
ajbspi-57894	34	4	and	and	CCONJ
ajbspi-57894	34	5	conditions	condition	NOUN
ajbspi-57894	34	6	were	be	AUX
ajbspi-57894	34	7	employed	employ	VERB
ajbspi-57894	34	8	:	:	PUNCT
ajbspi-57894	34	9	reagents	reagent	NOUN
ajbspi-57894	34	10	:	:	PUNCT
ajbspi-57894	34	11	7	7	NUM
ajbspi-57894	34	12	-	-	PUNCT
ajbspi-57894	34	13	aminocephalosporanic	aminocephalosporanic	ADJ
ajbspi-57894	34	14	acid	acid	NOUN
ajbspi-57894	34	15	(	(	PUNCT
ajbspi-57894	34	16	7	7	NUM
ajbspi-57894	34	17	-	-	PUNCT
ajbspi-57894	34	18	aca	aca	NOUN
ajbspi-57894	34	19	):	):	PUNCT
ajbspi-57894	34	20	the	the	DET
ajbspi-57894	34	21	primary	primary	ADJ
ajbspi-57894	34	22	starting	starting	NOUN
ajbspi-57894	34	23	material	material	NOUN
ajbspi-57894	34	24	for	for	ADP
ajbspi-57894	34	25	both	both	DET
ajbspi-57894	34	26	routes	route	NOUN
ajbspi-57894	34	27	.	.	PUNCT
ajbspi-57894	35	1	acyl	acyl	NOUN
ajbspi-57894	35	2	chlorides	chloride	NOUN
ajbspi-57894	35	3	:	:	PUNCT
ajbspi-57894	35	4	various	various	ADJ
ajbspi-57894	35	5	acyl	acyl	NOUN
ajbspi-57894	35	6	chlorides	chloride	NOUN
ajbspi-57894	35	7	were	be	AUX
ajbspi-57894	35	8	evaluated	evaluate	VERB
ajbspi-57894	35	9	for	for	ADP
ajbspi-57894	35	10	their	their	PRON
ajbspi-57894	35	11	reactivity	reactivity	NOUN
ajbspi-57894	35	12	and	and	CCONJ
ajbspi-57894	35	13	ability	ability	NOUN
ajbspi-57894	35	14	to	to	PART
ajbspi-57894	35	15	form	form	VERB
ajbspi-57894	35	16	the	the	DET
ajbspi-57894	35	17	desired	desire	VERB
ajbspi-57894	35	18	cefetamet	cefetamet	NOUN
ajbspi-57894	35	19	structure	structure	NOUN
ajbspi-57894	35	20	.	.	PUNCT
ajbspi-57894	36	1	acyl	acyl	NOUN
ajbspi-57894	36	2	chlorides	chloride	NOUN
ajbspi-57894	36	3	such	such	ADJ
ajbspi-57894	36	4	as	as	ADP
ajbspi-57894	36	5	phenylacetyl	phenylacetyl	PROPN
ajbspi-57894	36	6	chloride	chloride	NOUN
ajbspi-57894	36	7	were	be	AUX
ajbspi-57894	36	8	identified	identify	VERB
ajbspi-57894	36	9	as	as	ADP
ajbspi-57894	36	10	promising	promise	VERB
ajbspi-57894	36	11	candidates	candidate	NOUN
ajbspi-57894	36	12	.	.	PUNCT
ajbspi-57894	37	1	catalysts	catalyst	NOUN
ajbspi-57894	37	2	:	:	PUNCT
ajbspi-57894	37	3	different	different	ADJ
ajbspi-57894	37	4	catalytic	catalytic	ADJ
ajbspi-57894	37	5	systems	system	NOUN
ajbspi-57894	37	6	were	be	AUX
ajbspi-57894	37	7	tested	test	VERB
ajbspi-57894	37	8	to	to	PART
ajbspi-57894	37	9	enhance	enhance	VERB
ajbspi-57894	37	10	reaction	reaction	NOUN
ajbspi-57894	37	11	efficiency	efficiency	NOUN
ajbspi-57894	37	12	,	,	PUNCT
ajbspi-57894	37	13	including	include	VERB
ajbspi-57894	37	14	lewis	lewis	PROPN
ajbspi-57894	37	15	acids	acid	NOUN
ajbspi-57894	37	16	such	such	ADJ
ajbspi-57894	37	17	as	as	ADP
ajbspi-57894	37	18	aluminum	aluminum	NOUN
ajbspi-57894	37	19	chloride	chloride	NOUN
ajbspi-57894	37	20	and	and	CCONJ
ajbspi-57894	37	21	organic	organic	ADJ
ajbspi-57894	37	22	catalysts	catalyst	NOUN
ajbspi-57894	37	23	.	.	PUNCT
ajbspi-57894	38	1	reaction	reaction	NOUN
ajbspi-57894	38	2	conditions	condition	NOUN
ajbspi-57894	38	3	:	:	PUNCT
ajbspi-57894	38	4	temperature	temperature	NOUN
ajbspi-57894	38	5	:	:	PUNCT
ajbspi-57894	38	6	initial	initial	ADJ
ajbspi-57894	38	7	reactions	reaction	NOUN
ajbspi-57894	38	8	were	be	AUX
ajbspi-57894	38	9	conducted	conduct	VERB
ajbspi-57894	38	10	at	at	ADP
ajbspi-57894	38	11	ambient	ambient	ADJ
ajbspi-57894	38	12	temperatures	temperature	NOUN
ajbspi-57894	38	13	,	,	PUNCT
ajbspi-57894	38	14	followed	follow	VERB
ajbspi-57894	38	15	by	by	ADP
ajbspi-57894	38	16	experiments	experiment	NOUN
ajbspi-57894	38	17	to	to	PART
ajbspi-57894	38	18	assess	assess	VERB
ajbspi-57894	38	19	the	the	DET
ajbspi-57894	38	20	effects	effect	NOUN
ajbspi-57894	38	21	of	of	ADP
ajbspi-57894	38	22	elevated	elevated	ADJ
ajbspi-57894	38	23	temperatures	temperature	NOUN
ajbspi-57894	38	24	(	(	PUNCT
ajbspi-57894	38	25	up	up	ADP
ajbspi-57894	38	26	to	to	PART
ajbspi-57894	38	27	80	80	NUM
ajbspi-57894	38	28	°	°	NOUN
ajbspi-57894	38	29	c	c	NOUN
ajbspi-57894	38	30	)	)	PUNCT
ajbspi-57894	38	31	on	on	ADP
ajbspi-57894	38	32	reaction	reaction	NOUN
ajbspi-57894	38	33	rates	rate	NOUN
ajbspi-57894	38	34	and	and	CCONJ
ajbspi-57894	38	35	yields	yield	NOUN
ajbspi-57894	38	36	.	.	PUNCT
ajbspi-57894	39	1	solvent	solvent	NOUN
ajbspi-57894	39	2	systems	system	NOUN
ajbspi-57894	39	3	:	:	PUNCT
ajbspi-57894	39	4	a	a	DET
ajbspi-57894	39	5	variety	variety	NOUN
ajbspi-57894	39	6	of	of	ADP
ajbspi-57894	39	7	solvents	solvent	NOUN
ajbspi-57894	39	8	,	,	PUNCT
ajbspi-57894	39	9	including	include	VERB
ajbspi-57894	39	10	dichloromethane	dichloromethane	NOUN
ajbspi-57894	39	11	and	and	CCONJ
ajbspi-57894	39	12	acetonitrile	acetonitrile	NOUN
ajbspi-57894	39	13	,	,	PUNCT
ajbspi-57894	39	14	were	be	AUX
ajbspi-57894	39	15	screened	screen	VERB
ajbspi-57894	39	16	for	for	ADP
ajbspi-57894	39	17	their	their	PRON
ajbspi-57894	39	18	ability	ability	NOUN
ajbspi-57894	39	19	to	to	PART
ajbspi-57894	39	20	dissolve	dissolve	VERB
ajbspi-57894	39	21	the	the	DET
ajbspi-57894	39	22	reactants	reactant	NOUN
ajbspi-57894	39	23	and	and	CCONJ
ajbspi-57894	39	24	facilitate	facilitate	VERB
ajbspi-57894	39	25	the	the	DET
ajbspi-57894	39	26	reaction	reaction	NOUN
ajbspi-57894	39	27	.	.	PUNCT
ajbspi-57894	40	1	polar	polar	ADJ
ajbspi-57894	40	2	aprotic	aprotic	ADJ
ajbspi-57894	40	3	solvents	solvent	NOUN
ajbspi-57894	40	4	were	be	AUX
ajbspi-57894	40	5	preferred	prefer	VERB
ajbspi-57894	40	6	to	to	PART
ajbspi-57894	40	7	enhance	enhance	VERB
ajbspi-57894	40	8	reactivity	reactivity	NOUN
ajbspi-57894	40	9	.	.	PUNCT
ajbspi-57894	41	1	reaction	reaction	NOUN
ajbspi-57894	41	2	time	time	NOUN
ajbspi-57894	41	3	:	:	PUNCT
ajbspi-57894	41	4	the	the	DET
ajbspi-57894	41	5	reaction	reaction	NOUN
ajbspi-57894	41	6	times	time	NOUN
ajbspi-57894	41	7	were	be	AUX
ajbspi-57894	41	8	varied	varied	ADJ
ajbspi-57894	41	9	from	from	ADP
ajbspi-57894	41	10	several	several	ADJ
ajbspi-57894	41	11	hours	hour	NOUN
ajbspi-57894	41	12	to	to	ADP
ajbspi-57894	41	13	overnight	overnight	ADV
ajbspi-57894	41	14	,	,	PUNCT
ajbspi-57894	41	15	with	with	ADP
ajbspi-57894	41	16	continuous	continuous	ADJ
ajbspi-57894	41	17	monitoring	monitoring	NOUN
ajbspi-57894	41	18	to	to	PART
ajbspi-57894	41	19	optimize	optimize	VERB
ajbspi-57894	41	20	the	the	DET
ajbspi-57894	41	21	duration	duration	NOUN
ajbspi-57894	41	22	for	for	ADP
ajbspi-57894	41	23	maximum	maximum	ADJ
ajbspi-57894	41	24	yield	yield	NOUN
ajbspi-57894	41	25	.	.	PUNCT
ajbspi-57894	42	1	3	3	X
ajbspi-57894	42	2	.	.	X
ajbspi-57894	42	3	process	process	NOUN
ajbspi-57894	42	4	optimization	optimization	NOUN
ajbspi-57894	42	5	the	the	DET
ajbspi-57894	42	6	initial	initial	ADJ
ajbspi-57894	42	7	synthetic	synthetic	ADJ
ajbspi-57894	42	8	pathways	pathway	NOUN
ajbspi-57894	42	9	were	be	AUX
ajbspi-57894	42	10	further	far	ADV
ajbspi-57894	42	11	refined	refine	VERB
ajbspi-57894	42	12	through	through	ADP
ajbspi-57894	42	13	a	a	DET
ajbspi-57894	42	14	series	series	NOUN
ajbspi-57894	42	15	of	of	ADP
ajbspi-57894	42	16	optimization	optimization	NOUN
ajbspi-57894	42	17	experiments	experiment	NOUN
ajbspi-57894	42	18	.	.	PUNCT
ajbspi-57894	43	1	the	the	DET
ajbspi-57894	43	2	optimization	optimization	NOUN
ajbspi-57894	43	3	process	process	NOUN
ajbspi-57894	43	4	involved	involve	VERB
ajbspi-57894	43	5	the	the	DET
ajbspi-57894	43	6	following	follow	VERB
ajbspi-57894	43	7	steps	step	NOUN
ajbspi-57894	43	8	:	:	PUNCT
ajbspi-57894	43	9	design	design	NOUN
ajbspi-57894	43	10	of	of	ADP
ajbspi-57894	43	11	experiments	experiment	NOUN
ajbspi-57894	43	12	(	(	PUNCT
ajbspi-57894	43	13	doe	doe	NOUN
ajbspi-57894	43	14	):	):	PUNCT
ajbspi-57894	43	15	a	a	DET
ajbspi-57894	43	16	factorial	factorial	ADJ
ajbspi-57894	43	17	design	design	NOUN
ajbspi-57894	43	18	approach	approach	NOUN
ajbspi-57894	43	19	was	be	AUX
ajbspi-57894	43	20	employed	employ	VERB
ajbspi-57894	43	21	to	to	PART
ajbspi-57894	43	22	systematically	systematically	ADV
ajbspi-57894	43	23	evaluate	evaluate	VERB
ajbspi-57894	43	24	the	the	DET
ajbspi-57894	43	25	influence	influence	NOUN
ajbspi-57894	43	26	of	of	ADP
ajbspi-57894	43	27	multiple	multiple	ADJ
ajbspi-57894	43	28	factors	factor	NOUN
ajbspi-57894	43	29	on	on	ADP
ajbspi-57894	43	30	the	the	DET
ajbspi-57894	43	31	reaction	reaction	NOUN
ajbspi-57894	43	32	outcomes	outcome	NOUN
ajbspi-57894	43	33	.	.	PUNCT
ajbspi-57894	44	1	key	key	ADJ
ajbspi-57894	44	2	variables	variable	NOUN
ajbspi-57894	44	3	included	include	VERB
ajbspi-57894	44	4	temperature	temperature	NOUN
ajbspi-57894	44	5	,	,	PUNCT
ajbspi-57894	44	6	catalyst	catalyst	NOUN
ajbspi-57894	44	7	type	type	NOUN
ajbspi-57894	44	8	,	,	PUNCT
ajbspi-57894	44	9	solvent	solvent	NOUN
ajbspi-57894	44	10	,	,	PUNCT
ajbspi-57894	44	11	and	and	CCONJ
ajbspi-57894	44	12	acyl	acyl	NOUN
ajbspi-57894	44	13	chloride	chloride	NOUN
ajbspi-57894	44	14	concentration	concentration	NOUN
ajbspi-57894	44	15	.	.	PUNCT
ajbspi-57894	45	1	iterative	iterative	NOUN
ajbspi-57894	45	2	testing	testing	NOUN
ajbspi-57894	45	3	:	:	PUNCT
ajbspi-57894	45	4	iterative	iterative	NOUN
ajbspi-57894	45	5	testing	testing	NOUN
ajbspi-57894	45	6	was	be	AUX
ajbspi-57894	45	7	conducted	conduct	VERB
ajbspi-57894	45	8	based	base	VERB
ajbspi-57894	45	9	on	on	ADP
ajbspi-57894	45	10	initial	initial	ADJ
ajbspi-57894	45	11	results	result	NOUN
ajbspi-57894	45	12	.	.	PUNCT
ajbspi-57894	46	1	for	for	ADP
ajbspi-57894	46	2	instance	instance	NOUN
ajbspi-57894	46	3	,	,	PUNCT
ajbspi-57894	46	4	if	if	SCONJ
ajbspi-57894	46	5	a	a	DET
ajbspi-57894	46	6	certain	certain	ADJ
ajbspi-57894	46	7	solvent	solvent	NOUN
ajbspi-57894	46	8	or	or	CCONJ
ajbspi-57894	46	9	temperature	temperature	NOUN
ajbspi-57894	46	10	yielded	yield	VERB
ajbspi-57894	46	11	a	a	DET
ajbspi-57894	46	12	promising	promising	ADJ
ajbspi-57894	46	13	result	result	NOUN
ajbspi-57894	46	14	,	,	PUNCT
ajbspi-57894	46	15	subsequent	subsequent	ADJ
ajbspi-57894	46	16	experiments	experiment	NOUN
ajbspi-57894	46	17	focused	focus	VERB
ajbspi-57894	46	18	on	on	ADP
ajbspi-57894	46	19	fine	fine	ADV
ajbspi-57894	46	20	-	-	PUNCT
ajbspi-57894	46	21	tuning	tune	VERB
ajbspi-57894	46	22	those	those	DET
ajbspi-57894	46	23	conditions	condition	NOUN
ajbspi-57894	46	24	.	.	PUNCT
ajbspi-57894	47	1	reaction	reaction	NOUN
ajbspi-57894	47	2	parameters	parameter	NOUN
ajbspi-57894	47	3	such	such	ADJ
ajbspi-57894	47	4	as	as	ADP
ajbspi-57894	47	5	catalyst	catalyst	NOUN
ajbspi-57894	47	6	loading	loading	NOUN
ajbspi-57894	47	7	were	be	AUX
ajbspi-57894	47	8	adjusted	adjust	VERB
ajbspi-57894	47	9	incrementally	incrementally	ADV
ajbspi-57894	47	10	to	to	PART
ajbspi-57894	47	11	identify	identify	VERB
ajbspi-57894	47	12	the	the	DET
ajbspi-57894	47	13	optimal	optimal	ADJ
ajbspi-57894	47	14	amounts	amount	NOUN
ajbspi-57894	47	15	for	for	ADP
ajbspi-57894	47	16	enhanced	enhanced	ADJ
ajbspi-57894	47	17	efficiency	efficiency	NOUN
ajbspi-57894	47	18	.	.	PUNCT
ajbspi-57894	48	1	yield	yield	NOUN
ajbspi-57894	48	2	and	and	CCONJ
ajbspi-57894	48	3	purity	purity	NOUN
ajbspi-57894	48	4	assessment	assessment	NOUN
ajbspi-57894	48	5	:	:	PUNCT
ajbspi-57894	48	6	after	after	ADP
ajbspi-57894	48	7	each	each	DET
ajbspi-57894	48	8	round	round	NOUN
ajbspi-57894	48	9	of	of	ADP
ajbspi-57894	48	10	optimization	optimization	NOUN
ajbspi-57894	48	11	,	,	PUNCT
ajbspi-57894	48	12	the	the	DET
ajbspi-57894	48	13	products	product	NOUN
ajbspi-57894	48	14	were	be	AUX
ajbspi-57894	48	15	analyzed	analyze	VERB
ajbspi-57894	48	16	using	use	VERB
ajbspi-57894	48	17	highperformance	highperformance	NOUN
ajbspi-57894	48	18	liquid	liquid	ADJ
ajbspi-57894	48	19	chromatography	chromatography	NOUN
ajbspi-57894	48	20	(	(	PUNCT
ajbspi-57894	48	21	hplc	hplc	PROPN
ajbspi-57894	48	22	)	)	PUNCT
ajbspi-57894	48	23	to	to	PART
ajbspi-57894	48	24	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	VERB
ajbspi-57894	48	25	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	PUNCT
ajbspi-57894	48	26	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	ADJ
ajbspi-57894	48	27	volume	volume	NOUN
ajbspi-57894	48	28	04	04	NUM
ajbspi-57894	48	29	issue	issue	NOUN
ajbspi-57894	48	30	11	11	NUM
ajbspi-57894	48	31	-	-	SYM
ajbspi-57894	48	32	2024	2024	NUM
ajbspi-57894	48	33	4	4	NUM
ajbspi-57894	48	34	american	american	ADJ
ajbspi-57894	48	35	journal	journal	NOUN
ajbspi-57894	48	36	of	of	ADP
ajbspi-57894	48	37	biomedical	biomedical	PROPN
ajbspi-57894	48	38	science	science	PROPN
ajbspi-57894	48	39	&	&	CCONJ
ajbspi-57894	48	40	pharmaceutical	pharmaceutical	PROPN
ajbspi-57894	48	41	innovation	innovation	NOUN
ajbspi-57894	48	42	(	(	PUNCT
ajbspi-57894	48	43	issn	issn	PROPN
ajbspi-57894	48	44	–	–	PUNCT
ajbspi-57894	48	45	2771	2771	NUM
ajbspi-57894	48	46	-	-	SYM
ajbspi-57894	48	47	2753	2753	NUM
ajbspi-57894	48	48	)	)	PUNCT
ajbspi-57894	48	49	volume	volume	NOUN
ajbspi-57894	48	50	04	04	NUM
ajbspi-57894	48	51	issue	issue	NOUN
ajbspi-57894	48	52	11	11	NUM
ajbspi-57894	48	53	pages	page	NOUN
ajbspi-57894	48	54	:	:	PUNCT
ajbspi-57894	48	55	1	1	NUM
ajbspi-57894	48	56	-	-	SYM
ajbspi-57894	48	57	7	7	NUM
ajbspi-57894	48	58	oclc	oclc	PROPN
ajbspi-57894	48	59	–	–	PUNCT
ajbspi-57894	48	60	1121105677	1121105677	NUM
ajbspi-57894	48	61	publisher	publisher	NOUN
ajbspi-57894	48	62	:	:	PUNCT
ajbspi-57894	48	63	oscar	oscar	NOUN
ajbspi-57894	48	64	publishing	publishing	NOUN
ajbspi-57894	48	65	services	service	NOUN
ajbspi-57894	48	66	servi	servi	PROPN
ajbspi-57894	48	67	determine	determine	NOUN
ajbspi-57894	48	68	yield	yield	NOUN
ajbspi-57894	48	69	and	and	CCONJ
ajbspi-57894	48	70	purity	purity	NOUN
ajbspi-57894	48	71	.	.	PUNCT
ajbspi-57894	49	1	these	these	DET
ajbspi-57894	49	2	analyses	analysis	NOUN
ajbspi-57894	49	3	informed	inform	VERB
ajbspi-57894	49	4	subsequent	subsequent	ADJ
ajbspi-57894	49	5	rounds	round	NOUN
ajbspi-57894	49	6	of	of	ADP
ajbspi-57894	49	7	optimization	optimization	NOUN
ajbspi-57894	49	8	,	,	PUNCT
ajbspi-57894	49	9	allowing	allow	VERB
ajbspi-57894	49	10	for	for	ADP
ajbspi-57894	49	11	a	a	DET
ajbspi-57894	49	12	feedback	feedback	NOUN
ajbspi-57894	49	13	loop	loop	NOUN
ajbspi-57894	49	14	that	that	PRON
ajbspi-57894	49	15	guided	guide	VERB
ajbspi-57894	49	16	the	the	DET
ajbspi-57894	49	17	development	development	NOUN
ajbspi-57894	49	18	of	of	ADP
ajbspi-57894	49	19	the	the	DET
ajbspi-57894	49	20	most	most	ADV
ajbspi-57894	49	21	effective	effective	ADJ
ajbspi-57894	49	22	synthetic	synthetic	ADJ
ajbspi-57894	49	23	pathway	pathway	NOUN
ajbspi-57894	49	24	.	.	PUNCT
ajbspi-57894	50	1	purification	purification	NOUN
ajbspi-57894	50	2	and	and	CCONJ
ajbspi-57894	50	3	characterization	characterization	NOUN
ajbspi-57894	50	4	upon	upon	SCONJ
ajbspi-57894	50	5	successful	successful	ADJ
ajbspi-57894	50	6	synthesis	synthesis	NOUN
ajbspi-57894	50	7	of	of	ADP
ajbspi-57894	50	8	cefetamet	cefetamet	ADJ
ajbspi-57894	50	9	sodium	sodium	NOUN
ajbspi-57894	50	10	,	,	PUNCT
ajbspi-57894	50	11	purification	purification	NOUN
ajbspi-57894	50	12	and	and	CCONJ
ajbspi-57894	50	13	characterization	characterization	NOUN
ajbspi-57894	50	14	of	of	ADP
ajbspi-57894	50	15	the	the	DET
ajbspi-57894	50	16	final	final	ADJ
ajbspi-57894	50	17	product	product	NOUN
ajbspi-57894	50	18	were	be	AUX
ajbspi-57894	50	19	performed	perform	VERB
ajbspi-57894	50	20	to	to	PART
ajbspi-57894	50	21	ensure	ensure	VERB
ajbspi-57894	50	22	quality	quality	NOUN
ajbspi-57894	50	23	and	and	CCONJ
ajbspi-57894	50	24	compliance	compliance	NOUN
ajbspi-57894	50	25	with	with	ADP
ajbspi-57894	50	26	pharmaceutical	pharmaceutical	ADJ
ajbspi-57894	50	27	standards	standard	NOUN
ajbspi-57894	50	28	.	.	PUNCT
ajbspi-57894	51	1	purification	purification	NOUN
ajbspi-57894	51	2	methods	method	NOUN
ajbspi-57894	51	3	:	:	PUNCT
ajbspi-57894	51	4	crystallization	crystallization	NOUN
ajbspi-57894	51	5	:	:	PUNCT
ajbspi-57894	51	6	the	the	DET
ajbspi-57894	51	7	crude	crude	ADJ
ajbspi-57894	51	8	product	product	NOUN
ajbspi-57894	51	9	was	be	AUX
ajbspi-57894	51	10	purified	purify	VERB
ajbspi-57894	51	11	through	through	ADP
ajbspi-57894	51	12	recrystallization	recrystallization	NOUN
ajbspi-57894	51	13	,	,	PUNCT
ajbspi-57894	51	14	which	which	PRON
ajbspi-57894	51	15	was	be	AUX
ajbspi-57894	51	16	optimized	optimize	VERB
ajbspi-57894	51	17	by	by	ADP
ajbspi-57894	51	18	varying	vary	VERB
ajbspi-57894	51	19	solvent	solvent	ADJ
ajbspi-57894	51	20	combinations	combination	NOUN
ajbspi-57894	51	21	to	to	PART
ajbspi-57894	51	22	achieve	achieve	VERB
ajbspi-57894	51	23	the	the	DET
ajbspi-57894	51	24	best	good	ADJ
ajbspi-57894	51	25	crystallization	crystallization	NOUN
ajbspi-57894	51	26	conditions	condition	NOUN
ajbspi-57894	51	27	.	.	PUNCT
ajbspi-57894	52	1	column	column	NOUN
ajbspi-57894	52	2	chromatography	chromatography	NOUN
ajbspi-57894	52	3	:	:	PUNCT
ajbspi-57894	52	4	in	in	ADP
ajbspi-57894	52	5	cases	case	NOUN
ajbspi-57894	52	6	where	where	SCONJ
ajbspi-57894	52	7	crystallization	crystallization	NOUN
ajbspi-57894	52	8	was	be	AUX
ajbspi-57894	52	9	not	not	PART
ajbspi-57894	52	10	effective	effective	ADJ
ajbspi-57894	52	11	,	,	PUNCT
ajbspi-57894	52	12	column	column	NOUN
ajbspi-57894	52	13	chromatography	chromatography	NOUN
ajbspi-57894	52	14	was	be	AUX
ajbspi-57894	52	15	employed	employ	VERB
ajbspi-57894	52	16	to	to	PART
ajbspi-57894	52	17	separate	separate	ADJ
ajbspi-57894	52	18	impurities	impurity	NOUN
ajbspi-57894	52	19	and	and	CCONJ
ajbspi-57894	52	20	isolate	isolate	VERB
ajbspi-57894	52	21	the	the	DET
ajbspi-57894	52	22	desired	desire	VERB
ajbspi-57894	52	23	product	product	NOUN
ajbspi-57894	52	24	.	.	PUNCT
ajbspi-57894	53	1	silica	silica	NOUN
ajbspi-57894	53	2	gel	gel	NOUN
ajbspi-57894	53	3	was	be	AUX
ajbspi-57894	53	4	used	use	VERB
ajbspi-57894	53	5	as	as	ADP
ajbspi-57894	53	6	the	the	DET
ajbspi-57894	53	7	stationary	stationary	ADJ
ajbspi-57894	53	8	phase	phase	NOUN
ajbspi-57894	53	9	with	with	ADP
ajbspi-57894	53	10	appropriate	appropriate	ADJ
ajbspi-57894	53	11	elution	elution	NOUN
ajbspi-57894	53	12	solvents	solvent	NOUN
ajbspi-57894	53	13	.	.	PUNCT
ajbspi-57894	54	1	analytical	analytical	ADJ
ajbspi-57894	54	2	characterization	characterization	NOUN
ajbspi-57894	54	3	:	:	PUNCT
ajbspi-57894	54	4	hplc	hplc	NOUN
ajbspi-57894	54	5	analysis	analysis	NOUN
ajbspi-57894	54	6	:	:	PUNCT
ajbspi-57894	54	7	to	to	PART
ajbspi-57894	54	8	confirm	confirm	VERB
ajbspi-57894	54	9	the	the	DET
ajbspi-57894	54	10	purity	purity	NOUN
ajbspi-57894	54	11	of	of	ADP
ajbspi-57894	54	12	the	the	DET
ajbspi-57894	54	13	synthesized	synthesize	VERB
ajbspi-57894	54	14	cefetamet	cefetamet	NOUN
ajbspi-57894	54	15	sodium	sodium	NOUN
ajbspi-57894	54	16	,	,	PUNCT
ajbspi-57894	54	17	hplc	hplc	NOUN
ajbspi-57894	54	18	was	be	AUX
ajbspi-57894	54	19	utilized	utilize	VERB
ajbspi-57894	54	20	,	,	PUNCT
ajbspi-57894	54	21	establishing	establish	VERB
ajbspi-57894	54	22	a	a	DET
ajbspi-57894	54	23	standard	standard	ADJ
ajbspi-57894	54	24	curve	curve	NOUN
ajbspi-57894	54	25	using	use	VERB
ajbspi-57894	54	26	known	know	VERB
ajbspi-57894	54	27	concentrations	concentration	NOUN
ajbspi-57894	54	28	of	of	ADP
ajbspi-57894	54	29	cefetamet	cefetamet	ADJ
ajbspi-57894	54	30	sodium	sodium	NOUN
ajbspi-57894	54	31	for	for	ADP
ajbspi-57894	54	32	quantification	quantification	NOUN
ajbspi-57894	54	33	.	.	PUNCT
ajbspi-57894	55	1	nuclear	nuclear	ADJ
ajbspi-57894	55	2	magnetic	magnetic	ADJ
ajbspi-57894	55	3	resonance	resonance	NOUN
ajbspi-57894	55	4	(	(	PUNCT
ajbspi-57894	55	5	nmr	nmr	NOUN
ajbspi-57894	55	6	)	)	PUNCT
ajbspi-57894	55	7	spectroscopy	spectroscopy	NOUN
ajbspi-57894	55	8	:	:	PUNCT
ajbspi-57894	55	9	both	both	DET
ajbspi-57894	55	10	1h	1h	NUM
ajbspi-57894	55	11	and	and	CCONJ
ajbspi-57894	55	12	13c	13c	NOUN
ajbspi-57894	55	13	nmr	nmr	NOUN
ajbspi-57894	55	14	were	be	AUX
ajbspi-57894	55	15	performed	perform	VERB
ajbspi-57894	55	16	to	to	PART
ajbspi-57894	55	17	confirm	confirm	VERB
ajbspi-57894	55	18	the	the	DET
ajbspi-57894	55	19	structure	structure	NOUN
ajbspi-57894	55	20	of	of	ADP
ajbspi-57894	55	21	cefetamet	cefetamet	ADJ
ajbspi-57894	55	22	sodium	sodium	NOUN
ajbspi-57894	55	23	.	.	PUNCT
ajbspi-57894	56	1	the	the	DET
ajbspi-57894	56	2	chemical	chemical	ADJ
ajbspi-57894	56	3	shifts	shift	NOUN
ajbspi-57894	56	4	were	be	AUX
ajbspi-57894	56	5	compared	compare	VERB
ajbspi-57894	56	6	with	with	ADP
ajbspi-57894	56	7	literature	literature	NOUN
ajbspi-57894	56	8	values	value	NOUN
ajbspi-57894	56	9	to	to	PART
ajbspi-57894	56	10	ensure	ensure	VERB
ajbspi-57894	56	11	accurate	accurate	ADJ
ajbspi-57894	56	12	identification	identification	NOUN
ajbspi-57894	56	13	.	.	PUNCT
ajbspi-57894	57	1	mass	mass	ADJ
ajbspi-57894	57	2	spectrometry	spectrometry	NOUN
ajbspi-57894	57	3	(	(	PUNCT
ajbspi-57894	57	4	ms	ms	PROPN
ajbspi-57894	57	5	):	):	PUNCT
ajbspi-57894	57	6	mass	mass	ADJ
ajbspi-57894	57	7	spectrometry	spectrometry	NOUN
ajbspi-57894	57	8	was	be	AUX
ajbspi-57894	57	9	conducted	conduct	VERB
ajbspi-57894	57	10	to	to	PART
ajbspi-57894	57	11	verify	verify	VERB
ajbspi-57894	57	12	the	the	DET
ajbspi-57894	57	13	molecular	molecular	ADJ
ajbspi-57894	57	14	weight	weight	NOUN
ajbspi-57894	57	15	of	of	ADP
ajbspi-57894	57	16	the	the	DET
ajbspi-57894	57	17	final	final	ADJ
ajbspi-57894	57	18	product	product	NOUN
ajbspi-57894	57	19	,	,	PUNCT
ajbspi-57894	57	20	providing	provide	VERB
ajbspi-57894	57	21	further	further	ADJ
ajbspi-57894	57	22	confirmation	confirmation	NOUN
ajbspi-57894	57	23	of	of	ADP
ajbspi-57894	57	24	its	its	PRON
ajbspi-57894	57	25	identity	identity	NOUN
ajbspi-57894	57	26	.	.	PUNCT
ajbspi-57894	58	1	5	5	NUM
ajbspi-57894	58	2	.	.	X
ajbspi-57894	58	3	scale	scale	NOUN
ajbspi-57894	58	4	-	-	PUNCT
ajbspi-57894	58	5	up	up	ADP
ajbspi-57894	58	6	considerations	consideration	NOUN
ajbspi-57894	58	7	in	in	ADP
ajbspi-57894	58	8	addition	addition	NOUN
ajbspi-57894	58	9	to	to	ADP
ajbspi-57894	58	10	the	the	DET
ajbspi-57894	58	11	synthesis	synthesis	NOUN
ajbspi-57894	58	12	of	of	ADP
ajbspi-57894	58	13	cefetamet	cefetamet	ADJ
ajbspi-57894	58	14	sodium	sodium	NOUN
ajbspi-57894	58	15	,	,	PUNCT
ajbspi-57894	58	16	considerations	consideration	NOUN
ajbspi-57894	58	17	for	for	ADP
ajbspi-57894	58	18	scaling	scale	VERB
ajbspi-57894	58	19	up	up	ADP
ajbspi-57894	58	20	the	the	DET
ajbspi-57894	58	21	process	process	NOUN
ajbspi-57894	58	22	for	for	ADP
ajbspi-57894	58	23	commercial	commercial	ADJ
ajbspi-57894	58	24	production	production	NOUN
ajbspi-57894	58	25	were	be	AUX
ajbspi-57894	58	26	taken	take	VERB
ajbspi-57894	58	27	into	into	ADP
ajbspi-57894	58	28	account	account	NOUN
ajbspi-57894	58	29	.	.	PUNCT
ajbspi-57894	59	1	the	the	DET
ajbspi-57894	59	2	following	follow	VERB
ajbspi-57894	59	3	aspects	aspect	NOUN
ajbspi-57894	59	4	were	be	AUX
ajbspi-57894	59	5	addressed	address	VERB
ajbspi-57894	59	6	:	:	PUNCT
ajbspi-57894	59	7	equipment	equipment	NOUN
ajbspi-57894	59	8	selection	selection	NOUN
ajbspi-57894	59	9	:	:	PUNCT
ajbspi-57894	59	10	appropriate	appropriate	ADJ
ajbspi-57894	59	11	reaction	reaction	NOUN
ajbspi-57894	59	12	vessels	vessel	NOUN
ajbspi-57894	59	13	and	and	CCONJ
ajbspi-57894	59	14	equipment	equipment	NOUN
ajbspi-57894	59	15	were	be	AUX
ajbspi-57894	59	16	selected	select	VERB
ajbspi-57894	59	17	based	base	VERB
ajbspi-57894	59	18	on	on	ADP
ajbspi-57894	59	19	batch	batch	NOUN
ajbspi-57894	59	20	sizes	size	NOUN
ajbspi-57894	59	21	and	and	CCONJ
ajbspi-57894	59	22	desired	desire	VERB
ajbspi-57894	59	23	production	production	NOUN
ajbspi-57894	59	24	rates	rate	NOUN
ajbspi-57894	59	25	,	,	PUNCT
ajbspi-57894	59	26	ensuring	ensure	VERB
ajbspi-57894	59	27	they	they	PRON
ajbspi-57894	59	28	could	could	AUX
ajbspi-57894	59	29	accommodate	accommodate	VERB
ajbspi-57894	59	30	the	the	DET
ajbspi-57894	59	31	reaction	reaction	NOUN
ajbspi-57894	59	32	conditions	condition	NOUN
ajbspi-57894	59	33	and	and	CCONJ
ajbspi-57894	59	34	volumes	volume	NOUN
ajbspi-57894	59	35	necessary	necessary	ADJ
ajbspi-57894	59	36	for	for	ADP
ajbspi-57894	59	37	larger	large	ADJ
ajbspi-57894	59	38	-	-	PUNCT
ajbspi-57894	59	39	scale	scale	NOUN
ajbspi-57894	59	40	operations	operation	NOUN
ajbspi-57894	59	41	.	.	PUNCT
ajbspi-57894	60	1	cost	cost	NOUN
ajbspi-57894	60	2	analysis	analysis	NOUN
ajbspi-57894	60	3	:	:	PUNCT
ajbspi-57894	60	4	an	an	DET
ajbspi-57894	60	5	economic	economic	ADJ
ajbspi-57894	60	6	feasibility	feasibility	NOUN
ajbspi-57894	60	7	study	study	NOUN
ajbspi-57894	60	8	was	be	AUX
ajbspi-57894	60	9	conducted	conduct	VERB
ajbspi-57894	60	10	to	to	PART
ajbspi-57894	60	11	evaluate	evaluate	VERB
ajbspi-57894	60	12	the	the	DET
ajbspi-57894	60	13	costs	cost	NOUN
ajbspi-57894	60	14	associated	associate	VERB
ajbspi-57894	60	15	with	with	ADP
ajbspi-57894	60	16	raw	raw	ADJ
ajbspi-57894	60	17	materials	material	NOUN
ajbspi-57894	60	18	,	,	PUNCT
ajbspi-57894	60	19	reagents	reagent	NOUN
ajbspi-57894	60	20	,	,	PUNCT
ajbspi-57894	60	21	and	and	CCONJ
ajbspi-57894	60	22	equipment	equipment	NOUN
ajbspi-57894	60	23	for	for	ADP
ajbspi-57894	60	24	scaled	scale	VERB
ajbspi-57894	60	25	-	-	PUNCT
ajbspi-57894	60	26	up	up	ADP
ajbspi-57894	60	27	production	production	NOUN
ajbspi-57894	60	28	.	.	PUNCT
ajbspi-57894	61	1	this	this	DET
ajbspi-57894	61	2	analysis	analysis	NOUN
ajbspi-57894	61	3	provided	provide	VERB
ajbspi-57894	61	4	insights	insight	NOUN
ajbspi-57894	61	5	into	into	ADP
ajbspi-57894	61	6	the	the	DET
ajbspi-57894	61	7	financial	financial	ADJ
ajbspi-57894	61	8	viability	viability	NOUN
ajbspi-57894	61	9	of	of	ADP
ajbspi-57894	61	10	the	the	DET
ajbspi-57894	61	11	newly	newly	ADV
ajbspi-57894	61	12	developed	develop	VERB
ajbspi-57894	61	13	synthetic	synthetic	ADJ
ajbspi-57894	61	14	pathways	pathway	NOUN
ajbspi-57894	61	15	.	.	PUNCT
ajbspi-57894	62	1	environmental	environmental	ADJ
ajbspi-57894	62	2	impact	impact	NOUN
ajbspi-57894	62	3	:	:	PUNCT
ajbspi-57894	62	4	an	an	DET
ajbspi-57894	62	5	assessment	assessment	NOUN
ajbspi-57894	62	6	of	of	ADP
ajbspi-57894	62	7	the	the	DET
ajbspi-57894	62	8	environmental	environmental	ADJ
ajbspi-57894	62	9	impact	impact	NOUN
ajbspi-57894	62	10	of	of	ADP
ajbspi-57894	62	11	the	the	DET
ajbspi-57894	62	12	new	new	ADJ
ajbspi-57894	62	13	synthesis	synthesis	NOUN
ajbspi-57894	62	14	routes	route	NOUN
ajbspi-57894	62	15	was	be	AUX
ajbspi-57894	62	16	performed	perform	VERB
ajbspi-57894	62	17	,	,	PUNCT
ajbspi-57894	62	18	considering	consider	VERB
ajbspi-57894	62	19	waste	waste	NOUN
ajbspi-57894	62	20	generation	generation	NOUN
ajbspi-57894	62	21	and	and	CCONJ
ajbspi-57894	62	22	the	the	DET
ajbspi-57894	62	23	use	use	NOUN
ajbspi-57894	62	24	of	of	ADP
ajbspi-57894	62	25	green	green	ADJ
ajbspi-57894	62	26	chemistry	chemistry	NOUN
ajbspi-57894	62	27	principles	principle	NOUN
ajbspi-57894	62	28	.	.	PUNCT
ajbspi-57894	63	1	this	this	PRON
ajbspi-57894	63	2	included	include	VERB
ajbspi-57894	63	3	evaluating	evaluate	VERB
ajbspi-57894	63	4	solvent	solvent	ADJ
ajbspi-57894	63	5	recovery	recovery	NOUN
ajbspi-57894	63	6	and	and	CCONJ
ajbspi-57894	63	7	recycling	recycling	NOUN
ajbspi-57894	63	8	options	option	NOUN
ajbspi-57894	63	9	to	to	PART
ajbspi-57894	63	10	minimize	minimize	VERB
ajbspi-57894	63	11	environmental	environmental	ADJ
ajbspi-57894	63	12	footprints	footprint	NOUN
ajbspi-57894	63	13	.	.	PUNCT
ajbspi-57894	64	1	results	result	VERB
ajbspi-57894	64	2	the	the	DET
ajbspi-57894	64	3	synthesis	synthesis	NOUN
ajbspi-57894	64	4	of	of	ADP
ajbspi-57894	64	5	cefetamet	cefetamet	ADJ
ajbspi-57894	64	6	sodium	sodium	NOUN
ajbspi-57894	64	7	was	be	AUX
ajbspi-57894	64	8	successfully	successfully	ADV
ajbspi-57894	64	9	achieved	achieve	VERB
ajbspi-57894	64	10	through	through	ADP
ajbspi-57894	64	11	the	the	DET
ajbspi-57894	64	12	exploration	exploration	NOUN
ajbspi-57894	64	13	of	of	ADP
ajbspi-57894	64	14	two	two	NUM
ajbspi-57894	64	15	primary	primary	ADJ
ajbspi-57894	64	16	pathways	pathway	NOUN
ajbspi-57894	64	17	:	:	PUNCT
ajbspi-57894	64	18	the	the	DET
ajbspi-57894	64	19	direct	direct	ADJ
ajbspi-57894	64	20	acylation	acylation	NOUN
ajbspi-57894	64	21	method	method	NOUN
ajbspi-57894	64	22	(	(	PUNCT
ajbspi-57894	64	23	route	route	NOUN
ajbspi-57894	64	24	a	a	NOUN
ajbspi-57894	64	25	)	)	PUNCT
ajbspi-57894	64	26	and	and	CCONJ
ajbspi-57894	64	27	the	the	DET
ajbspi-57894	64	28	intermediary	intermediary	ADJ
ajbspi-57894	64	29	cyclization	cyclization	NOUN
ajbspi-57894	64	30	method	method	NOUN
ajbspi-57894	64	31	(	(	PUNCT
ajbspi-57894	64	32	route	route	NOUN
ajbspi-57894	64	33	b	b	PROPN
ajbspi-57894	64	34	)	)	PUNCT
ajbspi-57894	64	35	.	.	PUNCT
ajbspi-57894	65	1	each	each	DET
ajbspi-57894	65	2	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	NOUN
ajbspi-57894	65	3	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	AUX
ajbspi-57894	65	4	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	ADJ
ajbspi-57894	65	5	volume	volume	NOUN
ajbspi-57894	65	6	04	04	NUM
ajbspi-57894	65	7	issue	issue	NOUN
ajbspi-57894	65	8	11	11	NUM
ajbspi-57894	65	9	-	-	SYM
ajbspi-57894	65	10	2024	2024	NUM
ajbspi-57894	65	11	5	5	NUM
ajbspi-57894	65	12	american	american	ADJ
ajbspi-57894	65	13	journal	journal	PROPN
ajbspi-57894	65	14	of	of	ADP
ajbspi-57894	65	15	biomedical	biomedical	PROPN
ajbspi-57894	65	16	science	science	PROPN
ajbspi-57894	65	17	&	&	CCONJ
ajbspi-57894	65	18	pharmaceutical	pharmaceutical	PROPN
ajbspi-57894	65	19	innovation	innovation	NOUN
ajbspi-57894	65	20	(	(	PUNCT
ajbspi-57894	65	21	issn	issn	PROPN
ajbspi-57894	65	22	–	–	PUNCT
ajbspi-57894	65	23	2771	2771	NUM
ajbspi-57894	65	24	-	-	SYM
ajbspi-57894	65	25	2753	2753	NUM
ajbspi-57894	65	26	)	)	PUNCT
ajbspi-57894	65	27	volume	volume	NOUN
ajbspi-57894	65	28	04	04	NUM
ajbspi-57894	65	29	issue	issue	NOUN
ajbspi-57894	65	30	11	11	NUM
ajbspi-57894	65	31	pages	page	NOUN
ajbspi-57894	65	32	:	:	PUNCT
ajbspi-57894	65	33	1	1	NUM
ajbspi-57894	65	34	-	-	SYM
ajbspi-57894	65	35	7	7	NUM
ajbspi-57894	65	36	oclc	oclc	PROPN
ajbspi-57894	65	37	–	–	PUNCT
ajbspi-57894	65	38	1121105677	1121105677	NUM
ajbspi-57894	65	39	publisher	publisher	NOUN
ajbspi-57894	65	40	:	:	PUNCT
ajbspi-57894	65	41	oscar	oscar	NOUN
ajbspi-57894	65	42	publishing	publishing	NOUN
ajbspi-57894	65	43	services	service	NOUN
ajbspi-57894	65	44	servi	servi	PROPN
ajbspi-57894	65	45	pathway	pathway	NOUN
ajbspi-57894	65	46	was	be	AUX
ajbspi-57894	65	47	optimized	optimize	VERB
ajbspi-57894	65	48	for	for	ADP
ajbspi-57894	65	49	yield	yield	NOUN
ajbspi-57894	65	50	,	,	PUNCT
ajbspi-57894	65	51	purity	purity	NOUN
ajbspi-57894	65	52	,	,	PUNCT
ajbspi-57894	65	53	and	and	CCONJ
ajbspi-57894	65	54	efficiency	efficiency	NOUN
ajbspi-57894	65	55	,	,	PUNCT
ajbspi-57894	65	56	with	with	ADP
ajbspi-57894	65	57	the	the	DET
ajbspi-57894	65	58	following	follow	VERB
ajbspi-57894	65	59	results	result	NOUN
ajbspi-57894	65	60	:	:	PUNCT
ajbspi-57894	65	61	yield	yield	NOUN
ajbspi-57894	65	62	and	and	CCONJ
ajbspi-57894	65	63	purity	purity	NOUN
ajbspi-57894	65	64	assessment	assessment	NOUN
ajbspi-57894	65	65	direct	direct	ADJ
ajbspi-57894	65	66	acylation	acylation	NOUN
ajbspi-57894	65	67	method	method	NOUN
ajbspi-57894	65	68	(	(	PUNCT
ajbspi-57894	65	69	route	route	NOUN
ajbspi-57894	65	70	a	a	PRON
ajbspi-57894	65	71	):	):	PUNCT
ajbspi-57894	65	72	the	the	DET
ajbspi-57894	65	73	initial	initial	ADJ
ajbspi-57894	65	74	experiments	experiment	NOUN
ajbspi-57894	65	75	yielded	yield	VERB
ajbspi-57894	65	76	a	a	DET
ajbspi-57894	65	77	maximum	maximum	NOUN
ajbspi-57894	65	78	of	of	ADP
ajbspi-57894	65	79	75	75	NUM
ajbspi-57894	65	80	%	%	NOUN
ajbspi-57894	65	81	yield	yield	NOUN
ajbspi-57894	65	82	of	of	ADP
ajbspi-57894	65	83	cefetamet	cefetamet	ADJ
ajbspi-57894	65	84	sodium	sodium	NOUN
ajbspi-57894	65	85	.	.	PUNCT
ajbspi-57894	66	1	upon	upon	SCONJ
ajbspi-57894	66	2	optimization	optimization	NOUN
ajbspi-57894	66	3	of	of	ADP
ajbspi-57894	66	4	reaction	reaction	NOUN
ajbspi-57894	66	5	conditions	condition	NOUN
ajbspi-57894	66	6	,	,	PUNCT
ajbspi-57894	66	7	including	include	VERB
ajbspi-57894	66	8	catalyst	catalyst	NOUN
ajbspi-57894	66	9	type	type	NOUN
ajbspi-57894	66	10	and	and	CCONJ
ajbspi-57894	66	11	reaction	reaction	NOUN
ajbspi-57894	66	12	temperature	temperature	NOUN
ajbspi-57894	66	13	,	,	PUNCT
ajbspi-57894	66	14	the	the	DET
ajbspi-57894	66	15	yield	yield	NOUN
ajbspi-57894	66	16	improved	improve	VERB
ajbspi-57894	66	17	to	to	ADP
ajbspi-57894	66	18	88	88	NUM
ajbspi-57894	66	19	%	%	NOUN
ajbspi-57894	66	20	.	.	PUNCT
ajbspi-57894	67	1	hplc	hplc	NOUN
ajbspi-57894	67	2	analysis	analysis	NOUN
ajbspi-57894	67	3	indicated	indicate	VERB
ajbspi-57894	67	4	a	a	DET
ajbspi-57894	67	5	purity	purity	NOUN
ajbspi-57894	67	6	level	level	NOUN
ajbspi-57894	67	7	of	of	ADP
ajbspi-57894	67	8	95	95	NUM
ajbspi-57894	67	9	%	%	NOUN
ajbspi-57894	67	10	,	,	PUNCT
ajbspi-57894	67	11	with	with	SCONJ
ajbspi-57894	67	12	only	only	ADJ
ajbspi-57894	67	13	minor	minor	ADJ
ajbspi-57894	67	14	impurities	impurity	NOUN
ajbspi-57894	67	15	identified	identify	VERB
ajbspi-57894	67	16	,	,	PUNCT
ajbspi-57894	67	17	which	which	PRON
ajbspi-57894	67	18	were	be	AUX
ajbspi-57894	67	19	successfully	successfully	ADV
ajbspi-57894	67	20	removed	remove	VERB
ajbspi-57894	67	21	during	during	ADP
ajbspi-57894	67	22	purification	purification	NOUN
ajbspi-57894	67	23	.	.	PUNCT
ajbspi-57894	68	1	intermediary	intermediary	ADJ
ajbspi-57894	68	2	cyclization	cyclization	NOUN
ajbspi-57894	68	3	method	method	NOUN
ajbspi-57894	68	4	(	(	PUNCT
ajbspi-57894	68	5	route	route	NOUN
ajbspi-57894	68	6	b	b	NUM
ajbspi-57894	68	7	):	):	PUNCT
ajbspi-57894	68	8	this	this	DET
ajbspi-57894	68	9	method	method	NOUN
ajbspi-57894	68	10	initially	initially	ADV
ajbspi-57894	68	11	yielded	yield	VERB
ajbspi-57894	68	12	lower	low	ADJ
ajbspi-57894	68	13	results	result	NOUN
ajbspi-57894	68	14	,	,	PUNCT
ajbspi-57894	68	15	with	with	ADP
ajbspi-57894	68	16	maximum	maximum	ADJ
ajbspi-57894	68	17	yields	yield	NOUN
ajbspi-57894	68	18	of	of	ADP
ajbspi-57894	68	19	around	around	ADV
ajbspi-57894	68	20	65	65	NUM
ajbspi-57894	68	21	%	%	NOUN
ajbspi-57894	68	22	.	.	PUNCT
ajbspi-57894	69	1	after	after	ADP
ajbspi-57894	69	2	refining	refine	VERB
ajbspi-57894	69	3	the	the	DET
ajbspi-57894	69	4	reaction	reaction	NOUN
ajbspi-57894	69	5	conditions	condition	NOUN
ajbspi-57894	69	6	,	,	PUNCT
ajbspi-57894	69	7	including	include	VERB
ajbspi-57894	69	8	solvent	solvent	ADJ
ajbspi-57894	69	9	choice	choice	NOUN
ajbspi-57894	69	10	and	and	CCONJ
ajbspi-57894	69	11	reaction	reaction	NOUN
ajbspi-57894	69	12	time	time	NOUN
ajbspi-57894	69	13	,	,	PUNCT
ajbspi-57894	69	14	the	the	DET
ajbspi-57894	69	15	yield	yield	NOUN
ajbspi-57894	69	16	increased	increase	VERB
ajbspi-57894	69	17	to	to	ADP
ajbspi-57894	69	18	82	82	NUM
ajbspi-57894	69	19	%	%	NOUN
ajbspi-57894	69	20	.	.	PUNCT
ajbspi-57894	70	1	purity	purity	NOUN
ajbspi-57894	70	2	assessments	assessment	NOUN
ajbspi-57894	70	3	via	via	ADP
ajbspi-57894	70	4	hplc	hplc	NOUN
ajbspi-57894	70	5	indicated	indicate	VERB
ajbspi-57894	70	6	a	a	DET
ajbspi-57894	70	7	purity	purity	NOUN
ajbspi-57894	70	8	of	of	ADP
ajbspi-57894	70	9	92	92	NUM
ajbspi-57894	70	10	%	%	NOUN
ajbspi-57894	70	11	,	,	PUNCT
ajbspi-57894	70	12	with	with	ADP
ajbspi-57894	70	13	comparable	comparable	ADJ
ajbspi-57894	70	14	impurities	impurity	NOUN
ajbspi-57894	70	15	that	that	PRON
ajbspi-57894	70	16	were	be	AUX
ajbspi-57894	70	17	effectively	effectively	ADV
ajbspi-57894	70	18	eliminated	eliminate	VERB
ajbspi-57894	70	19	through	through	ADP
ajbspi-57894	70	20	crystallization	crystallization	NOUN
ajbspi-57894	70	21	.	.	PUNCT
ajbspi-57894	71	1	structural	structural	ADJ
ajbspi-57894	71	2	confirmation	confirmation	NOUN
ajbspi-57894	71	3	the	the	DET
ajbspi-57894	71	4	structure	structure	NOUN
ajbspi-57894	71	5	of	of	ADP
ajbspi-57894	71	6	cefetamet	cefetamet	ADJ
ajbspi-57894	71	7	sodium	sodium	NOUN
ajbspi-57894	71	8	was	be	AUX
ajbspi-57894	71	9	confirmed	confirm	VERB
ajbspi-57894	71	10	through	through	ADP
ajbspi-57894	71	11	multiple	multiple	ADJ
ajbspi-57894	71	12	analytical	analytical	ADJ
ajbspi-57894	71	13	techniques	technique	NOUN
ajbspi-57894	71	14	:	:	PUNCT
ajbspi-57894	71	15	nmr	nmr	NOUN
ajbspi-57894	71	16	spectroscopy	spectroscopy	NOUN
ajbspi-57894	71	17	:	:	PUNCT
ajbspi-57894	71	18	both	both	DET
ajbspi-57894	71	19	1h	1h	NUM
ajbspi-57894	71	20	and	and	CCONJ
ajbspi-57894	71	21	13c	13c	NOUN
ajbspi-57894	71	22	nmr	nmr	NOUN
ajbspi-57894	71	23	spectra	spectra	NOUN
ajbspi-57894	71	24	provided	provide	VERB
ajbspi-57894	71	25	consistent	consistent	ADJ
ajbspi-57894	71	26	chemical	chemical	ADJ
ajbspi-57894	71	27	shifts	shift	NOUN
ajbspi-57894	71	28	with	with	ADP
ajbspi-57894	71	29	those	those	PRON
ajbspi-57894	71	30	reported	report	VERB
ajbspi-57894	71	31	in	in	ADP
ajbspi-57894	71	32	the	the	DET
ajbspi-57894	71	33	literature	literature	NOUN
ajbspi-57894	71	34	for	for	ADP
ajbspi-57894	71	35	cefetamet	cefetamet	ADJ
ajbspi-57894	71	36	sodium	sodium	NOUN
ajbspi-57894	71	37	,	,	PUNCT
ajbspi-57894	71	38	confirming	confirm	VERB
ajbspi-57894	71	39	the	the	DET
ajbspi-57894	71	40	integrity	integrity	NOUN
ajbspi-57894	71	41	of	of	ADP
ajbspi-57894	71	42	the	the	DET
ajbspi-57894	71	43	synthesized	synthesize	VERB
ajbspi-57894	71	44	compound	compound	NOUN
ajbspi-57894	71	45	.	.	PUNCT
ajbspi-57894	72	1	mass	mass	PROPN
ajbspi-57894	72	2	spectrometry	spectrometry	NOUN
ajbspi-57894	72	3	:	:	PUNCT
ajbspi-57894	72	4	the	the	DET
ajbspi-57894	72	5	molecular	molecular	ADJ
ajbspi-57894	72	6	weight	weight	NOUN
ajbspi-57894	72	7	of	of	ADP
ajbspi-57894	72	8	the	the	DET
ajbspi-57894	72	9	final	final	ADJ
ajbspi-57894	72	10	product	product	NOUN
ajbspi-57894	72	11	was	be	AUX
ajbspi-57894	72	12	determined	determine	VERB
ajbspi-57894	72	13	to	to	PART
ajbspi-57894	72	14	be	be	AUX
ajbspi-57894	72	15	421	421	NUM
ajbspi-57894	72	16	g	g	NOUN
ajbspi-57894	72	17	/	/	SYM
ajbspi-57894	72	18	mol	mol	NOUN
ajbspi-57894	72	19	,	,	PUNCT
ajbspi-57894	72	20	which	which	PRON
ajbspi-57894	72	21	is	be	AUX
ajbspi-57894	72	22	consistent	consistent	ADJ
ajbspi-57894	72	23	with	with	ADP
ajbspi-57894	72	24	the	the	DET
ajbspi-57894	72	25	expected	expect	VERB
ajbspi-57894	72	26	molecular	molecular	ADJ
ajbspi-57894	72	27	weight	weight	NOUN
ajbspi-57894	72	28	for	for	ADP
ajbspi-57894	72	29	cefetamet	cefetamet	ADJ
ajbspi-57894	72	30	sodium	sodium	NOUN
ajbspi-57894	72	31	,	,	PUNCT
ajbspi-57894	72	32	further	far	ADV
ajbspi-57894	72	33	validating	validate	VERB
ajbspi-57894	72	34	the	the	DET
ajbspi-57894	72	35	synthesis	synthesis	NOUN
ajbspi-57894	72	36	.	.	PUNCT
ajbspi-57894	73	1	scale	scale	NOUN
ajbspi-57894	73	2	-	-	PUNCT
ajbspi-57894	73	3	up	up	ADP
ajbspi-57894	73	4	feasibility	feasibility	NOUN
ajbspi-57894	73	5	preliminary	preliminary	ADJ
ajbspi-57894	73	6	scale	scale	NOUN
ajbspi-57894	73	7	-	-	PUNCT
ajbspi-57894	73	8	up	up	ADP
ajbspi-57894	73	9	experiments	experiment	NOUN
ajbspi-57894	73	10	were	be	AUX
ajbspi-57894	73	11	conducted	conduct	VERB
ajbspi-57894	73	12	to	to	PART
ajbspi-57894	73	13	assess	assess	VERB
ajbspi-57894	73	14	the	the	DET
ajbspi-57894	73	15	practicality	practicality	NOUN
ajbspi-57894	73	16	of	of	ADP
ajbspi-57894	73	17	the	the	DET
ajbspi-57894	73	18	synthetic	synthetic	ADJ
ajbspi-57894	73	19	routes	route	NOUN
ajbspi-57894	73	20	for	for	ADP
ajbspi-57894	73	21	larger	large	ADJ
ajbspi-57894	73	22	-	-	PUNCT
ajbspi-57894	73	23	scale	scale	NOUN
ajbspi-57894	73	24	production	production	NOUN
ajbspi-57894	73	25	.	.	PUNCT
ajbspi-57894	74	1	initial	initial	ADJ
ajbspi-57894	74	2	evaluations	evaluation	NOUN
ajbspi-57894	74	3	indicated	indicate	VERB
ajbspi-57894	74	4	that	that	SCONJ
ajbspi-57894	74	5	both	both	DET
ajbspi-57894	74	6	pathways	pathway	NOUN
ajbspi-57894	74	7	could	could	AUX
ajbspi-57894	74	8	be	be	AUX
ajbspi-57894	74	9	adapted	adapt	VERB
ajbspi-57894	74	10	for	for	ADP
ajbspi-57894	74	11	batch	batch	NOUN
ajbspi-57894	74	12	production	production	NOUN
ajbspi-57894	74	13	without	without	ADP
ajbspi-57894	74	14	significant	significant	ADJ
ajbspi-57894	74	15	loss	loss	NOUN
ajbspi-57894	74	16	in	in	ADP
ajbspi-57894	74	17	yield	yield	NOUN
ajbspi-57894	74	18	or	or	CCONJ
ajbspi-57894	74	19	purity	purity	NOUN
ajbspi-57894	74	20	.	.	PUNCT
ajbspi-57894	75	1	the	the	DET
ajbspi-57894	75	2	economic	economic	ADJ
ajbspi-57894	75	3	analysis	analysis	NOUN
ajbspi-57894	75	4	suggested	suggest	VERB
ajbspi-57894	75	5	that	that	SCONJ
ajbspi-57894	75	6	the	the	DET
ajbspi-57894	75	7	direct	direct	ADJ
ajbspi-57894	75	8	acylation	acylation	NOUN
ajbspi-57894	75	9	method	method	NOUN
ajbspi-57894	75	10	would	would	AUX
ajbspi-57894	75	11	be	be	AUX
ajbspi-57894	75	12	more	more	ADJ
ajbspi-57894	75	13	cost	cost	NOUN
ajbspi-57894	75	14	-	-	PUNCT
ajbspi-57894	75	15	effective	effective	ADJ
ajbspi-57894	75	16	due	due	ADP
ajbspi-57894	75	17	to	to	ADP
ajbspi-57894	75	18	fewer	few	ADJ
ajbspi-57894	75	19	steps	step	NOUN
ajbspi-57894	75	20	and	and	CCONJ
ajbspi-57894	75	21	lower	low	ADJ
ajbspi-57894	75	22	reagent	reagent	ADJ
ajbspi-57894	75	23	costs	cost	NOUN
ajbspi-57894	75	24	.	.	PUNCT
ajbspi-57894	76	1	discussion	discussion	NOUN
ajbspi-57894	76	2	the	the	DET
ajbspi-57894	76	3	results	result	NOUN
ajbspi-57894	76	4	of	of	ADP
ajbspi-57894	76	5	this	this	DET
ajbspi-57894	76	6	study	study	NOUN
ajbspi-57894	76	7	demonstrate	demonstrate	VERB
ajbspi-57894	76	8	that	that	SCONJ
ajbspi-57894	76	9	novel	novel	ADJ
ajbspi-57894	76	10	synthetic	synthetic	ADJ
ajbspi-57894	76	11	pathways	pathway	NOUN
ajbspi-57894	76	12	for	for	ADP
ajbspi-57894	76	13	cefetamet	cefetamet	ADJ
ajbspi-57894	76	14	sodium	sodium	NOUN
ajbspi-57894	76	15	can	can	AUX
ajbspi-57894	76	16	significantly	significantly	ADV
ajbspi-57894	76	17	enhance	enhance	VERB
ajbspi-57894	76	18	both	both	DET
ajbspi-57894	76	19	yield	yield	NOUN
ajbspi-57894	76	20	and	and	CCONJ
ajbspi-57894	76	21	purity	purity	NOUN
ajbspi-57894	76	22	compared	compare	VERB
ajbspi-57894	76	23	to	to	ADP
ajbspi-57894	76	24	traditional	traditional	ADJ
ajbspi-57894	76	25	methods	method	NOUN
ajbspi-57894	76	26	.	.	PUNCT
ajbspi-57894	77	1	the	the	DET
ajbspi-57894	77	2	direct	direct	ADJ
ajbspi-57894	77	3	acylation	acylation	NOUN
ajbspi-57894	77	4	method	method	NOUN
ajbspi-57894	77	5	emerged	emerge	VERB
ajbspi-57894	77	6	as	as	ADP
ajbspi-57894	77	7	the	the	DET
ajbspi-57894	77	8	superior	superior	ADJ
ajbspi-57894	77	9	approach	approach	NOUN
ajbspi-57894	77	10	,	,	PUNCT
ajbspi-57894	77	11	offering	offer	VERB
ajbspi-57894	77	12	a	a	DET
ajbspi-57894	77	13	streamlined	streamlined	ADJ
ajbspi-57894	77	14	synthesis	synthesis	NOUN
ajbspi-57894	77	15	process	process	NOUN
ajbspi-57894	77	16	that	that	PRON
ajbspi-57894	77	17	minimizes	minimize	VERB
ajbspi-57894	77	18	waste	waste	NOUN
ajbspi-57894	77	19	and	and	CCONJ
ajbspi-57894	77	20	maximizes	maximize	VERB
ajbspi-57894	77	21	efficiency	efficiency	NOUN
ajbspi-57894	77	22	.	.	PUNCT
ajbspi-57894	78	1	comparison	comparison	NOUN
ajbspi-57894	78	2	of	of	ADP
ajbspi-57894	78	3	synthetic	synthetic	ADJ
ajbspi-57894	78	4	pathways	pathway	NOUN
ajbspi-57894	78	5	the	the	DET
ajbspi-57894	78	6	comparative	comparative	ADJ
ajbspi-57894	78	7	analysis	analysis	NOUN
ajbspi-57894	78	8	of	of	ADP
ajbspi-57894	78	9	the	the	DET
ajbspi-57894	78	10	two	two	NUM
ajbspi-57894	78	11	synthetic	synthetic	ADJ
ajbspi-57894	78	12	routes	route	NOUN
ajbspi-57894	78	13	indicates	indicate	VERB
ajbspi-57894	78	14	that	that	SCONJ
ajbspi-57894	78	15	the	the	DET
ajbspi-57894	78	16	direct	direct	ADJ
ajbspi-57894	78	17	acylation	acylation	NOUN
ajbspi-57894	78	18	method	method	NOUN
ajbspi-57894	78	19	benefits	benefit	NOUN
ajbspi-57894	78	20	from	from	ADP
ajbspi-57894	78	21	fewer	few	ADJ
ajbspi-57894	78	22	steps	step	NOUN
ajbspi-57894	78	23	and	and	CCONJ
ajbspi-57894	78	24	less	less	ADJ
ajbspi-57894	78	25	complexity	complexity	NOUN
ajbspi-57894	78	26	,	,	PUNCT
ajbspi-57894	78	27	resulting	result	VERB
ajbspi-57894	78	28	in	in	ADP
ajbspi-57894	78	29	higher	high	ADJ
ajbspi-57894	78	30	yields	yield	NOUN
ajbspi-57894	78	31	and	and	CCONJ
ajbspi-57894	78	32	purities	purity	NOUN
ajbspi-57894	78	33	.	.	PUNCT
ajbspi-57894	79	1	the	the	DET
ajbspi-57894	79	2	use	use	NOUN
ajbspi-57894	79	3	of	of	ADP
ajbspi-57894	79	4	optimized	optimize	VERB
ajbspi-57894	79	5	catalysts	catalyst	NOUN
ajbspi-57894	79	6	and	and	CCONJ
ajbspi-57894	79	7	solvents	solvent	NOUN
ajbspi-57894	79	8	in	in	ADP
ajbspi-57894	79	9	this	this	DET
ajbspi-57894	79	10	method	method	NOUN
ajbspi-57894	79	11	also	also	ADV
ajbspi-57894	79	12	highlights	highlight	VERB
ajbspi-57894	79	13	the	the	DET
ajbspi-57894	79	14	importance	importance	NOUN
ajbspi-57894	79	15	of	of	ADP
ajbspi-57894	79	16	selecting	select	VERB
ajbspi-57894	79	17	appropriate	appropriate	ADJ
ajbspi-57894	79	18	reaction	reaction	NOUN
ajbspi-57894	79	19	conditions	condition	NOUN
ajbspi-57894	79	20	to	to	PART
ajbspi-57894	79	21	enhance	enhance	VERB
ajbspi-57894	79	22	product	product	NOUN
ajbspi-57894	79	23	outcomes	outcome	NOUN
ajbspi-57894	79	24	.	.	PUNCT
ajbspi-57894	80	1	in	in	ADP
ajbspi-57894	80	2	contrast	contrast	NOUN
ajbspi-57894	80	3	,	,	PUNCT
ajbspi-57894	80	4	the	the	DET
ajbspi-57894	80	5	intermediary	intermediary	ADJ
ajbspi-57894	80	6	cyclization	cyclization	NOUN
ajbspi-57894	80	7	method	method	NOUN
ajbspi-57894	80	8	,	,	PUNCT
ajbspi-57894	80	9	while	while	SCONJ
ajbspi-57894	80	10	effective	effective	ADJ
ajbspi-57894	80	11	,	,	PUNCT
ajbspi-57894	80	12	involved	involve	VERB
ajbspi-57894	80	13	more	more	ADJ
ajbspi-57894	80	14	complex	complex	ADJ
ajbspi-57894	80	15	steps	step	NOUN
ajbspi-57894	80	16	that	that	PRON
ajbspi-57894	80	17	hindered	hinder	VERB
ajbspi-57894	80	18	overall	overall	ADJ
ajbspi-57894	80	19	efficiency	efficiency	NOUN
ajbspi-57894	80	20	.	.	PUNCT
ajbspi-57894	81	1	implications	implication	NOUN
ajbspi-57894	81	2	for	for	ADP
ajbspi-57894	81	3	antibiotic	antibiotic	ADJ
ajbspi-57894	81	4	production	production	NOUN
ajbspi-57894	81	5	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	NOUN
ajbspi-57894	81	6	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	AUX
ajbspi-57894	81	7	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	ADJ
ajbspi-57894	81	8	volume	volume	NOUN
ajbspi-57894	81	9	04	04	NUM
ajbspi-57894	81	10	issue	issue	NOUN
ajbspi-57894	81	11	11	11	NUM
ajbspi-57894	81	12	-	-	SYM
ajbspi-57894	81	13	2024	2024	NUM
ajbspi-57894	81	14	6	6	NUM
ajbspi-57894	81	15	american	american	ADJ
ajbspi-57894	81	16	journal	journal	NOUN
ajbspi-57894	81	17	of	of	ADP
ajbspi-57894	81	18	biomedical	biomedical	PROPN
ajbspi-57894	81	19	science	science	PROPN
ajbspi-57894	81	20	&	&	CCONJ
ajbspi-57894	81	21	pharmaceutical	pharmaceutical	PROPN
ajbspi-57894	81	22	innovation	innovation	NOUN
ajbspi-57894	81	23	(	(	PUNCT
ajbspi-57894	81	24	issn	issn	PROPN
ajbspi-57894	81	25	–	–	PUNCT
ajbspi-57894	81	26	2771	2771	NUM
ajbspi-57894	81	27	-	-	SYM
ajbspi-57894	81	28	2753	2753	NUM
ajbspi-57894	81	29	)	)	PUNCT
ajbspi-57894	81	30	volume	volume	NOUN
ajbspi-57894	81	31	04	04	NUM
ajbspi-57894	81	32	issue	issue	NOUN
ajbspi-57894	81	33	11	11	NUM
ajbspi-57894	81	34	pages	page	NOUN
ajbspi-57894	81	35	:	:	PUNCT
ajbspi-57894	81	36	1	1	NUM
ajbspi-57894	81	37	-	-	SYM
ajbspi-57894	81	38	7	7	NUM
ajbspi-57894	81	39	oclc	oclc	PROPN
ajbspi-57894	81	40	–	–	PUNCT
ajbspi-57894	81	41	1121105677	1121105677	NUM
ajbspi-57894	81	42	publisher	publisher	NOUN
ajbspi-57894	81	43	:	:	PUNCT
ajbspi-57894	81	44	oscar	oscar	NOUN
ajbspi-57894	81	45	publishing	publish	VERB
ajbspi-57894	81	46	services	service	NOUN
ajbspi-57894	81	47	servi	servi	VERB
ajbspi-57894	81	48	the	the	DET
ajbspi-57894	81	49	ability	ability	NOUN
ajbspi-57894	81	50	to	to	PART
ajbspi-57894	81	51	synthesize	synthesize	VERB
ajbspi-57894	81	52	cefetamet	cefetamet	ADJ
ajbspi-57894	81	53	sodium	sodium	NOUN
ajbspi-57894	81	54	with	with	ADP
ajbspi-57894	81	55	higher	high	ADJ
ajbspi-57894	81	56	yields	yield	NOUN
ajbspi-57894	81	57	and	and	CCONJ
ajbspi-57894	81	58	purities	purity	NOUN
ajbspi-57894	81	59	has	have	VERB
ajbspi-57894	81	60	significant	significant	ADJ
ajbspi-57894	81	61	implications	implication	NOUN
ajbspi-57894	81	62	for	for	ADP
ajbspi-57894	81	63	its	its	PRON
ajbspi-57894	81	64	commercial	commercial	ADJ
ajbspi-57894	81	65	production	production	NOUN
ajbspi-57894	81	66	.	.	PUNCT
ajbspi-57894	82	1	as	as	SCONJ
ajbspi-57894	82	2	antibiotic	antibiotic	ADJ
ajbspi-57894	82	3	resistance	resistance	NOUN
ajbspi-57894	82	4	becomes	become	VERB
ajbspi-57894	82	5	an	an	DET
ajbspi-57894	82	6	increasingly	increasingly	ADV
ajbspi-57894	82	7	urgent	urgent	ADJ
ajbspi-57894	82	8	public	public	ADJ
ajbspi-57894	82	9	health	health	NOUN
ajbspi-57894	82	10	issue	issue	NOUN
ajbspi-57894	82	11	,	,	PUNCT
ajbspi-57894	82	12	efficient	efficient	ADJ
ajbspi-57894	82	13	production	production	NOUN
ajbspi-57894	82	14	methods	method	NOUN
ajbspi-57894	82	15	are	be	AUX
ajbspi-57894	82	16	essential	essential	ADJ
ajbspi-57894	82	17	to	to	PART
ajbspi-57894	82	18	ensure	ensure	VERB
ajbspi-57894	82	19	a	a	DET
ajbspi-57894	82	20	stable	stable	ADJ
ajbspi-57894	82	21	supply	supply	NOUN
ajbspi-57894	82	22	of	of	ADP
ajbspi-57894	82	23	effective	effective	ADJ
ajbspi-57894	82	24	treatments	treatment	NOUN
ajbspi-57894	82	25	.	.	PUNCT
ajbspi-57894	83	1	the	the	DET
ajbspi-57894	83	2	processes	process	NOUN
ajbspi-57894	83	3	developed	develop	VERB
ajbspi-57894	83	4	in	in	ADP
ajbspi-57894	83	5	this	this	DET
ajbspi-57894	83	6	study	study	NOUN
ajbspi-57894	83	7	align	align	VERB
ajbspi-57894	83	8	with	with	ADP
ajbspi-57894	83	9	the	the	DET
ajbspi-57894	83	10	principles	principle	NOUN
ajbspi-57894	83	11	of	of	ADP
ajbspi-57894	83	12	green	green	ADJ
ajbspi-57894	83	13	chemistry	chemistry	NOUN
ajbspi-57894	83	14	,	,	PUNCT
ajbspi-57894	83	15	promoting	promote	VERB
ajbspi-57894	83	16	sustainability	sustainability	NOUN
ajbspi-57894	83	17	in	in	ADP
ajbspi-57894	83	18	pharmaceutical	pharmaceutical	NOUN
ajbspi-57894	83	19	manufacturing	manufacturing	NOUN
ajbspi-57894	83	20	by	by	ADP
ajbspi-57894	83	21	minimizing	minimize	VERB
ajbspi-57894	83	22	waste	waste	NOUN
ajbspi-57894	83	23	and	and	CCONJ
ajbspi-57894	83	24	reducing	reduce	VERB
ajbspi-57894	83	25	hazardous	hazardous	ADJ
ajbspi-57894	83	26	chemical	chemical	NOUN
ajbspi-57894	83	27	usage	usage	NOUN
ajbspi-57894	83	28	.	.	PUNCT
ajbspi-57894	84	1	future	future	ADJ
ajbspi-57894	84	2	directions	direction	NOUN
ajbspi-57894	84	3	future	future	ADJ
ajbspi-57894	84	4	work	work	NOUN
ajbspi-57894	84	5	should	should	AUX
ajbspi-57894	84	6	focus	focus	VERB
ajbspi-57894	84	7	on	on	ADP
ajbspi-57894	84	8	further	far	ADV
ajbspi-57894	84	9	optimizing	optimize	VERB
ajbspi-57894	84	10	the	the	DET
ajbspi-57894	84	11	selected	select	VERB
ajbspi-57894	84	12	synthetic	synthetic	ADJ
ajbspi-57894	84	13	route	route	NOUN
ajbspi-57894	84	14	,	,	PUNCT
ajbspi-57894	84	15	particularly	particularly	ADV
ajbspi-57894	84	16	in	in	ADP
ajbspi-57894	84	17	terms	term	NOUN
ajbspi-57894	84	18	of	of	ADP
ajbspi-57894	84	19	scaleup	scaleup	NOUN
ajbspi-57894	84	20	processes	process	NOUN
ajbspi-57894	84	21	and	and	CCONJ
ajbspi-57894	84	22	long	long	ADJ
ajbspi-57894	84	23	-	-	PUNCT
ajbspi-57894	84	24	term	term	NOUN
ajbspi-57894	84	25	stability	stability	NOUN
ajbspi-57894	84	26	of	of	ADP
ajbspi-57894	84	27	the	the	DET
ajbspi-57894	84	28	product	product	NOUN
ajbspi-57894	84	29	.	.	PUNCT
ajbspi-57894	85	1	exploring	explore	VERB
ajbspi-57894	85	2	alternative	alternative	ADJ
ajbspi-57894	85	3	catalysts	catalyst	NOUN
ajbspi-57894	85	4	and	and	CCONJ
ajbspi-57894	85	5	solvents	solvent	NOUN
ajbspi-57894	85	6	that	that	PRON
ajbspi-57894	85	7	align	align	VERB
ajbspi-57894	85	8	with	with	ADP
ajbspi-57894	85	9	green	green	ADJ
ajbspi-57894	85	10	chemistry	chemistry	NOUN
ajbspi-57894	85	11	principles	principle	NOUN
ajbspi-57894	85	12	could	could	AUX
ajbspi-57894	85	13	also	also	ADV
ajbspi-57894	85	14	enhance	enhance	VERB
ajbspi-57894	85	15	the	the	DET
ajbspi-57894	85	16	sustainability	sustainability	NOUN
ajbspi-57894	85	17	of	of	ADP
ajbspi-57894	85	18	the	the	DET
ajbspi-57894	85	19	process	process	NOUN
ajbspi-57894	85	20	.	.	PUNCT
ajbspi-57894	86	1	additionally	additionally	ADV
ajbspi-57894	86	2	,	,	PUNCT
ajbspi-57894	86	3	investigating	investigate	VERB
ajbspi-57894	86	4	the	the	DET
ajbspi-57894	86	5	pharmacological	pharmacological	ADJ
ajbspi-57894	86	6	properties	property	NOUN
ajbspi-57894	86	7	of	of	ADP
ajbspi-57894	86	8	the	the	DET
ajbspi-57894	86	9	synthesized	synthesize	VERB
ajbspi-57894	86	10	cefetamet	cefetamet	NOUN
ajbspi-57894	86	11	sodium	sodium	NOUN
ajbspi-57894	86	12	in	in	ADP
ajbspi-57894	86	13	comparative	comparative	ADJ
ajbspi-57894	86	14	studies	study	NOUN
ajbspi-57894	86	15	with	with	ADP
ajbspi-57894	86	16	commercially	commercially	ADV
ajbspi-57894	86	17	available	available	ADJ
ajbspi-57894	86	18	formulations	formulation	NOUN
ajbspi-57894	86	19	would	would	AUX
ajbspi-57894	86	20	provide	provide	VERB
ajbspi-57894	86	21	valuable	valuable	ADJ
ajbspi-57894	86	22	insights	insight	NOUN
ajbspi-57894	86	23	into	into	ADP
ajbspi-57894	86	24	its	its	PRON
ajbspi-57894	86	25	efficacy	efficacy	NOUN
ajbspi-57894	86	26	and	and	CCONJ
ajbspi-57894	86	27	potential	potential	ADJ
ajbspi-57894	86	28	advantages	advantage	NOUN
ajbspi-57894	86	29	.	.	PUNCT
ajbspi-57894	87	1	conclusion	conclusion	NOUN
ajbspi-57894	87	2	in	in	ADP
ajbspi-57894	87	3	conclusion	conclusion	NOUN
ajbspi-57894	87	4	,	,	PUNCT
ajbspi-57894	87	5	the	the	DET
ajbspi-57894	87	6	study	study	NOUN
ajbspi-57894	87	7	successfully	successfully	ADV
ajbspi-57894	87	8	developed	develop	VERB
ajbspi-57894	87	9	and	and	CCONJ
ajbspi-57894	87	10	optimized	optimize	VERB
ajbspi-57894	87	11	new	new	ADJ
ajbspi-57894	87	12	synthetic	synthetic	ADJ
ajbspi-57894	87	13	pathways	pathway	NOUN
ajbspi-57894	87	14	for	for	ADP
ajbspi-57894	87	15	cefetamet	cefetamet	ADJ
ajbspi-57894	87	16	sodium	sodium	NOUN
ajbspi-57894	87	17	,	,	PUNCT
ajbspi-57894	87	18	demonstrating	demonstrate	VERB
ajbspi-57894	87	19	significant	significant	ADJ
ajbspi-57894	87	20	improvements	improvement	NOUN
ajbspi-57894	87	21	in	in	ADP
ajbspi-57894	87	22	yield	yield	NOUN
ajbspi-57894	87	23	,	,	PUNCT
ajbspi-57894	87	24	purity	purity	NOUN
ajbspi-57894	87	25	,	,	PUNCT
ajbspi-57894	87	26	and	and	CCONJ
ajbspi-57894	87	27	environmental	environmental	ADJ
ajbspi-57894	87	28	sustainability	sustainability	NOUN
ajbspi-57894	87	29	compared	compare	VERB
ajbspi-57894	87	30	to	to	ADP
ajbspi-57894	87	31	traditional	traditional	ADJ
ajbspi-57894	87	32	methods	method	NOUN
ajbspi-57894	87	33	.	.	PUNCT
ajbspi-57894	88	1	the	the	DET
ajbspi-57894	88	2	direct	direct	ADJ
ajbspi-57894	88	3	acylation	acylation	NOUN
ajbspi-57894	88	4	method	method	NOUN
ajbspi-57894	88	5	,	,	PUNCT
ajbspi-57894	88	6	in	in	ADP
ajbspi-57894	88	7	particular	particular	ADJ
ajbspi-57894	88	8	,	,	PUNCT
ajbspi-57894	88	9	offers	offer	VERB
ajbspi-57894	88	10	a	a	DET
ajbspi-57894	88	11	streamlined	streamlined	ADJ
ajbspi-57894	88	12	approach	approach	NOUN
ajbspi-57894	88	13	that	that	PRON
ajbspi-57894	88	14	could	could	AUX
ajbspi-57894	88	15	facilitate	facilitate	VERB
ajbspi-57894	88	16	the	the	DET
ajbspi-57894	88	17	large	large	ADJ
ajbspi-57894	88	18	-	-	PUNCT
ajbspi-57894	88	19	scale	scale	NOUN
ajbspi-57894	88	20	production	production	NOUN
ajbspi-57894	88	21	of	of	ADP
ajbspi-57894	88	22	this	this	DET
ajbspi-57894	88	23	critical	critical	ADJ
ajbspi-57894	88	24	antibiotic	antibiotic	NOUN
ajbspi-57894	88	25	.	.	PUNCT
ajbspi-57894	89	1	the	the	DET
ajbspi-57894	89	2	findings	finding	NOUN
ajbspi-57894	89	3	contribute	contribute	VERB
ajbspi-57894	89	4	to	to	ADP
ajbspi-57894	89	5	the	the	DET
ajbspi-57894	89	6	ongoing	ongoing	ADJ
ajbspi-57894	89	7	efforts	effort	NOUN
ajbspi-57894	89	8	to	to	PART
ajbspi-57894	89	9	enhance	enhance	VERB
ajbspi-57894	89	10	antibiotic	antibiotic	ADJ
ajbspi-57894	89	11	manufacturing	manufacturing	NOUN
ajbspi-57894	89	12	practices	practice	NOUN
ajbspi-57894	89	13	and	and	CCONJ
ajbspi-57894	89	14	address	address	VERB
ajbspi-57894	89	15	the	the	DET
ajbspi-57894	89	16	challenges	challenge	NOUN
ajbspi-57894	89	17	posed	pose	VERB
ajbspi-57894	89	18	by	by	ADP
ajbspi-57894	89	19	antibiotic	antibiotic	ADJ
ajbspi-57894	89	20	resistance	resistance	NOUN
ajbspi-57894	89	21	.	.	PUNCT
ajbspi-57894	90	1	continued	continue	VERB
ajbspi-57894	90	2	research	research	NOUN
ajbspi-57894	90	3	and	and	CCONJ
ajbspi-57894	90	4	development	development	NOUN
ajbspi-57894	90	5	in	in	ADP
ajbspi-57894	90	6	this	this	DET
ajbspi-57894	90	7	area	area	NOUN
ajbspi-57894	90	8	will	will	AUX
ajbspi-57894	90	9	be	be	AUX
ajbspi-57894	90	10	vital	vital	ADJ
ajbspi-57894	90	11	for	for	ADP
ajbspi-57894	90	12	ensuring	ensure	VERB
ajbspi-57894	90	13	the	the	DET
ajbspi-57894	90	14	availability	availability	NOUN
ajbspi-57894	90	15	of	of	ADP
ajbspi-57894	90	16	effective	effective	ADJ
ajbspi-57894	90	17	antibiotic	antibiotic	ADJ
ajbspi-57894	90	18	treatments	treatment	NOUN
ajbspi-57894	90	19	in	in	ADP
ajbspi-57894	90	20	the	the	DET
ajbspi-57894	90	21	future	future	NOUN
ajbspi-57894	90	22	.	.	PUNCT
ajbspi-57894	91	1	reference	reference	NOUN
ajbspi-57894	91	2	1.todd	1.todd	NUM
ajbspi-57894	91	3	w.	w.	NOUN
ajbspi-57894	91	4	m.	m.	NOUN
ajbspi-57894	91	5	;	;	PUNCT
ajbspi-57894	91	6	cefpodoxime	cefpodoxime	NOUN
ajbspi-57894	91	7	proxetil	proxetil	NOUN
ajbspi-57894	91	8	:	:	PUNCT
ajbspi-57894	91	9	a	a	DET
ajbspi-57894	91	10	comprehensive	comprehensive	ADJ
ajbspi-57894	91	11	review	review	NOUN
ajbspi-57894	91	12	int	int	NOUN
ajbspi-57894	91	13	.	.	PUNCT
ajbspi-57894	92	1	j.	j.	PROPN
ajbspi-57894	92	2	antimicrobial	antimicrobial	ADJ
ajbspi-57894	92	3	agents	agent	NOUN
ajbspi-57894	92	4	,	,	PUNCT
ajbspi-57894	92	5	4	4	NUM
ajbspi-57894	92	6	,	,	PUNCT
ajbspi-57894	92	7	1994	1994	NUM
ajbspi-57894	92	8	,	,	PUNCT
ajbspi-57894	92	9	37	37	NUM
ajbspi-57894	92	10	-	-	SYM
ajbspi-57894	92	11	62	62	NUM
ajbspi-57894	92	12	.	.	PUNCT
ajbspi-57894	93	1	2.bayer	2.bayer	NUM
ajbspi-57894	93	2	t	t	PROPN
ajbspi-57894	93	3	,	,	PUNCT
ajbspi-57894	93	4	zhou	zhou	PROPN
ajbspi-57894	93	5	w	w	PROPN
ajbspi-57894	93	6	,	,	PUNCT
ajbspi-57894	93	7	holzhauer	holzhauer	PROPN
ajbspi-57894	93	8	k	k	PROPN
ajbspi-57894	93	9	,	,	PUNCT
ajbspi-57894	93	10	schiigerl	schiigerl	PROPN
ajbspi-57894	93	11	k.	k.	PROPN
ajbspi-57894	93	12	:	:	PUNCT
ajbspi-57894	94	1	investigations	investigation	NOUN
ajbspi-57894	94	2	of	of	ADP
ajbspi-57894	94	3	cephalosporin	cephalosporin	NOUN
ajbspi-57894	94	4	c	c	NOUN
ajbspi-57894	94	5	production	production	NOUN
ajbspi-57894	94	6	in	in	ADP
ajbspi-57894	94	7	an	an	DET
ajbspi-57894	94	8	airlift	airlift	NOUN
ajbspi-57894	94	9	tower	tower	NOUN
ajbspi-57894	94	10	loop	loop	NOUN
ajbspi-57894	94	11	reactor	reactor	NOUN
ajbspi-57894	94	12	.	.	PUNCT
ajbspi-57894	95	1	appl	appl	PROPN
ajbspi-57894	95	2	microbiol	microbiol	PROPN
ajbspi-57894	95	3	biotechnol	biotechnol	PROPN
ajbspi-57894	95	4	,	,	PUNCT
ajbspi-57894	95	5	1989	1989	NUM
ajbspi-57894	95	6	;	;	PUNCT
ajbspi-57894	95	7	30:26	30:26	NUM
ajbspi-57894	95	8	-	-	SYM
ajbspi-57894	95	9	33	33	NUM
ajbspi-57894	95	10	.	.	PUNCT
ajbspi-57894	96	1	3.heim	3.heim	NUM
ajbspi-57894	96	2	j	j	PROPN
ajbspi-57894	96	3	,	,	PUNCT
ajbspi-57894	96	4	shen	shen	PROPN
ajbspi-57894	96	5	yq	yq	PROPN
ajbspi-57894	96	6	,	,	PUNCT
ajbspi-57894	96	7	wolfe	wolfe	PROPN
ajbspi-57894	96	8	s	s	PROPN
ajbspi-57894	96	9	,	,	PUNCT
ajbspi-57894	96	10	demain	demain	PROPN
ajbspi-57894	96	11	al	al	PROPN
ajbspi-57894	96	12	.	.	PUNCT
ajbspi-57894	96	13	:	:	PUNCT
ajbspi-57894	97	1	regulation	regulation	NOUN
ajbspi-57894	97	2	of	of	ADP
ajbspi-57894	97	3	isopenicillin	isopenicillin	NOUN
ajbspi-57894	97	4	n	n	PRON
ajbspi-57894	97	5	synthetase	synthetase	NOUN
ajbspi-57894	97	6	by	by	ADP
ajbspi-57894	97	7	carbon	carbon	NOUN
ajbspi-57894	97	8	source	source	NOUN
ajbspi-57894	97	9	during	during	ADP
ajbspi-57894	97	10	the	the	DET
ajbspi-57894	97	11	fermentation	fermentation	NOUN
ajbspi-57894	97	12	of	of	ADP
ajbspi-57894	97	13	cephalosporium	cephalosporium	NOUN
ajbspi-57894	97	14	acremonium	acremonium	NOUN
ajbspi-57894	97	15	.	.	PUNCT
ajbspi-57894	98	1	appl	appl	PROPN
ajbspi-57894	98	2	microbiol	microbiol	PROPN
ajbspi-57894	98	3	biotechnol	biotechnol	PROPN
ajbspi-57894	98	4	1984	1984	NUM
ajbspi-57894	98	5	;	;	PUNCT
ajbspi-57894	98	6	19:2326	19:2326	NUM
ajbspi-57894	98	7	.	.	X
ajbspi-57894	99	1	4.dollery	4.dollery	NUM
ajbspi-57894	99	2	,	,	PUNCT
ajbspi-57894	99	3	c.	c.	PROPN
ajbspi-57894	99	4	(	(	PUNCT
ajbspi-57894	99	5	1999	1999	NUM
ajbspi-57894	99	6	)	)	PUNCT
ajbspi-57894	99	7	therapeutic	therapeutic	ADJ
ajbspi-57894	99	8	drugs	drug	NOUN
ajbspi-57894	99	9	.	.	PUNCT
ajbspi-57894	100	1	churchill	churchill	PROPN
ajbspi-57894	100	2	.	.	PUNCT
ajbspi-57894	101	1	3rd	3rd	ADJ
ajbspi-57894	101	2	ed	ed	NOUN
ajbspi-57894	101	3	,	,	PUNCT
ajbspi-57894	101	4	livingstone	livingstone	PROPN
ajbspi-57894	101	5	,	,	PUNCT
ajbspi-57894	101	6	edinburgh	edinburgh	PROPN
ajbspi-57894	101	7	.	.	PUNCT
ajbspi-57894	102	1	5.cephalosporins	5.cephalosporins	NUM
ajbspi-57894	102	2	and	and	CCONJ
ajbspi-57894	102	3	penicillin	penicillin	NOUN
ajbspi-57894	102	4	,	,	PUNCT
ajbspi-57894	102	5	chemistry	chemistry	NOUN
ajbspi-57894	102	6	and	and	CCONJ
ajbspi-57894	102	7	biology	biology	NOUN
ajbspi-57894	102	8	.	.	PUNCT
ajbspi-57894	103	1	edited	edit	VERB
ajbspi-57894	103	2	by	by	ADP
ajbspi-57894	103	3	e.	e.	PROPN
ajbspi-57894	103	4	h.	h.	PROPN
ajbspi-57894	103	5	flynn	flynn	PROPN
ajbspi-57894	103	6	,	,	PUNCT
ajbspi-57894	103	7	academic	academic	ADJ
ajbspi-57894	103	8	press	press	NOUN
ajbspi-57894	103	9	,	,	PUNCT
ajbspi-57894	103	10	new	new	PROPN
ajbspi-57894	103	11	york	york	PROPN
ajbspi-57894	103	12	and	and	CCONJ
ajbspi-57894	103	13	london	london	PROPN
ajbspi-57894	103	14	,	,	PUNCT
ajbspi-57894	103	15	84	84	NUM
ajbspi-57894	103	16	,	,	PUNCT
ajbspi-57894	103	17	1972	1972	NUM
ajbspi-57894	103	18	.	.	PUNCT
ajbspi-57894	104	1	6.jiang	6.jiang	NUM
ajbspi-57894	104	2	jia	jia	PROPN
ajbspi-57894	104	3	-	-	PUNCT
ajbspi-57894	104	4	feng	feng	PROPN
ajbspi-57894	104	5	(	(	PUNCT
ajbspi-57894	104	6	lunan	lunan	PROPN
ajbspi-57894	104	7	pharmaceutical	pharmaceutical	PROPN
ajbspi-57894	104	8	share	share	PROPN
ajbspi-57894	104	9	limited	limit	VERB
ajbspi-57894	104	10	corporation	corporation	NOUN
ajbspi-57894	104	11	,	,	PUNCT
ajbspi-57894	104	12	linyi	linyi	PROPN
ajbspi-57894	104	13	276006	276006	NUM
ajbspi-57894	104	14	)	)	PUNCT
ajbspi-57894	104	15	;	;	PUNCT
ajbspi-57894	104	16	synthesis	synthesis	NOUN
ajbspi-57894	104	17	of	of	ADP
ajbspi-57894	104	18	cefetamet	cefetamet	ADJ
ajbspi-57894	104	19	pivoxil	pivoxil	NOUN
ajbspi-57894	104	20	hydrochloride[j	hydrochloride[j	PROPN
ajbspi-57894	104	21	]	]	PUNCT
ajbspi-57894	104	22	;	;	PUNCT
ajbspi-57894	104	23	qilu	qilu	VERB
ajbspi-57894	104	24	pharmaceutical	pharmaceutical	PROPN
ajbspi-57894	104	25	affairs;2008	affairs;2008	PROPN
ajbspi-57894	104	26	-	-	PUNCT
ajbspi-57894	104	27	08	08	NUM
ajbspi-57894	104	28	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	NOUN
ajbspi-57894	104	29	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	AUX
ajbspi-57894	104	30	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	ADJ
ajbspi-57894	104	31	volume	volume	NOUN
ajbspi-57894	104	32	04	04	NUM
ajbspi-57894	104	33	issue	issue	NOUN
ajbspi-57894	104	34	11	11	NUM
ajbspi-57894	104	35	-	-	SYM
ajbspi-57894	104	36	2024	2024	NUM
ajbspi-57894	104	37	7	7	NUM
ajbspi-57894	104	38	american	american	ADJ
ajbspi-57894	104	39	journal	journal	PROPN
ajbspi-57894	104	40	of	of	ADP
ajbspi-57894	104	41	biomedical	biomedical	PROPN
ajbspi-57894	104	42	science	science	PROPN
ajbspi-57894	104	43	&	&	CCONJ
ajbspi-57894	104	44	pharmaceutical	pharmaceutical	PROPN
ajbspi-57894	104	45	innovation	innovation	NOUN
ajbspi-57894	104	46	(	(	PUNCT
ajbspi-57894	104	47	issn	issn	PROPN
ajbspi-57894	104	48	–	–	PUNCT
ajbspi-57894	104	49	2771	2771	NUM
ajbspi-57894	104	50	-	-	SYM
ajbspi-57894	104	51	2753	2753	NUM
ajbspi-57894	104	52	)	)	PUNCT
ajbspi-57894	104	53	volume	volume	NOUN
ajbspi-57894	104	54	04	04	NUM
ajbspi-57894	104	55	issue	issue	NOUN
ajbspi-57894	104	56	11	11	NUM
ajbspi-57894	104	57	pages	page	NOUN
ajbspi-57894	104	58	:	:	PUNCT
ajbspi-57894	104	59	1	1	NUM
ajbspi-57894	104	60	-	-	SYM
ajbspi-57894	104	61	7	7	NUM
ajbspi-57894	104	62	oclc	oclc	PROPN
ajbspi-57894	104	63	–	–	PUNCT
ajbspi-57894	104	64	1121105677	1121105677	NUM
ajbspi-57894	104	65	publisher	publisher	NOUN
ajbspi-57894	104	66	:	:	PUNCT
ajbspi-57894	104	67	oscar	oscar	NOUN
ajbspi-57894	104	68	publishing	publishing	NOUN
ajbspi-57894	104	69	services	service	NOUN
ajbspi-57894	104	70	servi	servi	PROPN
ajbspi-57894	104	71	7.muthadi	7.muthadi	PROPN
ajbspi-57894	104	72	f.j	f.j	PROPN
ajbspi-57894	104	73	.	.	PROPN
ajbspi-57894	104	74	;	;	PUNCT
ajbspi-57894	104	75	hassan	hassan	PROPN
ajbspi-57894	104	76	m.	m.	PROPN
ajbspi-57894	104	77	a.	a.	PROPN
ajbspi-57894	104	78	;	;	PUNCT
ajbspi-57894	104	79	florey	florey	PROPN
ajbspi-57894	104	80	,	,	PUNCT
ajbspi-57894	104	81	k.	k.	PROPN
ajbspi-57894	104	82	;	;	PUNCT
ajbspi-57894	104	83	(	(	PUNCT
ajbspi-57894	104	84	ed	ed	NOUN
ajbspi-57894	104	85	.	.	PUNCT
ajbspi-57894	104	86	)	)	PUNCT
ajbspi-57894	105	1	analytical	analytical	ADJ
ajbspi-57894	105	2	profiles	profile	NOUN
ajbspi-57894	105	3	of	of	ADP
ajbspi-57894	105	4	drug	drug	NOUN
ajbspi-57894	105	5	substances	substance	NOUN
ajbspi-57894	105	6	,	,	PUNCT
ajbspi-57894	105	7	academy	academy	NOUN
ajbspi-57894	105	8	press	press	NOUN
ajbspi-57894	105	9	,	,	PUNCT
ajbspi-57894	105	10	new	new	PROPN
ajbspi-57894	105	11	york	york	PROPN
ajbspi-57894	105	12	,	,	PUNCT
ajbspi-57894	105	13	vol	vol	NOUN
ajbspi-57894	105	14	.	.	PROPN
ajbspi-57894	105	15	11	11	NUM
ajbspi-57894	105	16	,	,	PUNCT
ajbspi-57894	105	17	1982	1982	NUM
ajbspi-57894	105	18	,	,	PUNCT
ajbspi-57894	105	19	159	159	NUM
ajbspi-57894	105	20	.	.	PUNCT
ajbspi-57894	106	1	8.united	8.united	NUM
ajbspi-57894	106	2	states	state	NOUN
ajbspi-57894	106	3	xxii	xxii	NOUN
ajbspi-57894	106	4	pharmacopeia	pharmacopeia	PROPN
ajbspi-57894	106	5	,	,	PUNCT
ajbspi-57894	106	6	the	the	DET
ajbspi-57894	106	7	united	united	PROPN
ajbspi-57894	106	8	states	states	PROPN
ajbspi-57894	106	9	pharmacopeia	pharmacopeia	PROPN
ajbspi-57894	106	10	convention	convention	PROPN
ajbspi-57894	106	11	inc	inc	PROPN
ajbspi-57894	106	12	.	.	PROPN
ajbspi-57894	106	13	,	,	PUNCT
ajbspi-57894	106	14	12601	12601	NUM
ajbspi-57894	106	15	twin	twin	PROPN
ajbspi-57894	106	16	brook	brook	PROPN
ajbspi-57894	106	17	parkway	parkway	PROPN
ajbspi-57894	106	18	,	,	PUNCT
ajbspi-57894	106	19	rockville	rockville	PROPN
ajbspi-57894	106	20	,	,	PUNCT
ajbspi-57894	106	21	md	md	PROPN
ajbspi-57894	106	22	20852	20852	NUM
ajbspi-57894	106	23	,	,	PUNCT
ajbspi-57894	106	24	1990	1990	NUM
ajbspi-57894	106	25	,	,	PUNCT
ajbspi-57894	106	26	249250	249250	NUM
ajbspi-57894	106	27	.	.	PUNCT
ajbspi-57894	107	1	9.indian	9.indian	NUM
ajbspi-57894	107	2	pharmacopeia	pharmacopeia	NOUN
ajbspi-57894	107	3	,	,	PUNCT
ajbspi-57894	107	4	ministry	ministry	PROPN
ajbspi-57894	107	5	of	of	ADP
ajbspi-57894	107	6	health	health	PROPN
ajbspi-57894	107	7	and	and	CCONJ
ajbspi-57894	107	8	family	family	NOUN
ajbspi-57894	107	9	welfare	welfare	NOUN
ajbspi-57894	107	10	,	,	PUNCT
ajbspi-57894	107	11	govt	govt	NOUN
ajbspi-57894	107	12	.	.	PUNCT
ajbspi-57894	107	13	of	of	ADP
ajbspi-57894	107	14	india	india	PROPN
ajbspi-57894	107	15	,	,	PUNCT
ajbspi-57894	107	16	new	new	ADJ
ajbspi-57894	107	17	delhi	delhi	PROPN
ajbspi-57894	107	18	;	;	PUNCT
ajbspi-57894	107	19	controller	controller	NOUN
ajbspi-57894	107	20	of	of	ADP
ajbspi-57894	107	21	publication	publication	NOUN
ajbspi-57894	107	22	,	,	PUNCT
ajbspi-57894	107	23	2nd	2nd	ADJ
ajbspi-57894	107	24	ed	ed	NOUN
ajbspi-57894	107	25	,	,	PUNCT
ajbspi-57894	107	26	1996	1996	NUM
ajbspi-57894	107	27	,	,	PUNCT
ajbspi-57894	107	28	a-740	a-740	NOUN
ajbspi-57894	107	29	10.indian	10.indian	NUM
ajbspi-57894	107	30	pharmacopeia	pharmacopeia	NOUN
ajbspi-57894	107	31	,	,	PUNCT
ajbspi-57894	107	32	ministry	ministry	PROPN
ajbspi-57894	107	33	of	of	ADP
ajbspi-57894	107	34	health	health	PROPN
ajbspi-57894	107	35	and	and	CCONJ
ajbspi-57894	107	36	family	family	NOUN
ajbspi-57894	107	37	welfare	welfare	NOUN
ajbspi-57894	107	38	,	,	PUNCT
ajbspi-57894	107	39	govt	govt	NOUN
ajbspi-57894	107	40	.	.	PUNCT
ajbspi-57894	107	41	of	of	ADP
ajbspi-57894	107	42	india	india	PROPN
ajbspi-57894	107	43	,	,	PUNCT
ajbspi-57894	107	44	new	new	ADJ
ajbspi-57894	107	45	delhi	delhi	PROPN
ajbspi-57894	107	46	;	;	PUNCT
ajbspi-57894	107	47	controller	controller	NOUN
ajbspi-57894	107	48	of	of	ADP
ajbspi-57894	107	49	publication	publication	NOUN
ajbspi-57894	107	50	,	,	PUNCT
ajbspi-57894	107	51	4th	4th	ADJ
ajbspi-57894	107	52	ed	ed	NOUN
ajbspi-57894	107	53	,	,	PUNCT
ajbspi-57894	107	54	1996	1996	NUM
ajbspi-57894	107	55	,	,	PUNCT
ajbspi-57894	107	56	a-54	a-54	PROPN
ajbspi-57894	107	57	11.xian	11.xian	NUM
ajbspi-57894	107	58	yang1,long	yang1,long	NOUN
ajbspi-57894	107	59	enwu1,yuan	enwu1,yuan	PUNCT
ajbspi-57894	108	1	haoyu2(1.sichuan	haoyu2(1.sichuan	PROPN
ajbspi-57894	108	2	provincial	provincial	ADJ
ajbspi-57894	108	3	people	people	NOUN
ajbspi-57894	108	4	's	's	PART
ajbspi-57894	108	5	hospital	hospital	NOUN
ajbspi-57894	108	6	,	,	PUNCT
ajbspi-57894	108	7	sichuan	sichuan	PROPN
ajbspi-57894	108	8	academy	academy	PROPN
ajbspi-57894	108	9	of	of	ADP
ajbspi-57894	108	10	medical	medical	ADJ
ajbspi-57894	108	11	science	science	PROPN
ajbspi-57894	108	12	,	,	PUNCT
ajbspi-57894	108	13	chengdu	chengdu	PROPN
ajbspi-57894	108	14	,	,	PUNCT
ajbspi-57894	108	15	sichuan	sichuan	PROPN
ajbspi-57894	108	16	,	,	PUNCT
ajbspi-57894	108	17	china	china	PROPN
ajbspi-57894	108	18	610072;2.416	610072;2.416	NUM
ajbspi-57894	108	19	hospital	hospital	NOUN
ajbspi-57894	108	20	of	of	ADP
ajbspi-57894	108	21	nuclear	nuclear	ADJ
ajbspi-57894	108	22	industry	industry	NOUN
ajbspi-57894	108	23	ministry	ministry	PROPN
ajbspi-57894	108	24	,	,	PUNCT
ajbspi-57894	108	25	chengdu	chengdu	PROPN
ajbspi-57894	108	26	,	,	PUNCT
ajbspi-57894	108	27	sichuan	sichuan	PROPN
ajbspi-57894	108	28	,	,	PUNCT
ajbspi-57894	108	29	china	china	PROPN
ajbspi-57894	108	30	610051	610051	NUM
ajbspi-57894	108	31	)	)	PUNCT
ajbspi-57894	108	32	;	;	PUNCT
ajbspi-57894	108	33	determination	determination	NOUN
ajbspi-57894	108	34	of	of	ADP
ajbspi-57894	108	35	cefetamet	cefetamet	ADJ
ajbspi-57894	108	36	pivoxil	pivoxil	NOUN
ajbspi-57894	108	37	hydrochloride	hydrochloride	NOUN
ajbspi-57894	108	38	capsules	capsule	NOUN
ajbspi-57894	108	39	by	by	ADP
ajbspi-57894	108	40	rp	rp	NOUN
ajbspi-57894	108	41	-	-	PUNCT
ajbspi-57894	108	42	hplc[j];china	hplc[j];china	ADJ
ajbspi-57894	108	43	pharmaceuticals;201007	pharmaceuticals;201007	PROPN
ajbspi-57894	108	44	12.fang	12.fang	PROPN
ajbspi-57894	108	45	yulan	yulan	PROPN
ajbspi-57894	108	46	,	,	PUNCT
ajbspi-57894	108	47	harbin	harbin	PROPN
ajbspi-57894	108	48	pharmaceutical	pharmaceutical	PROPN
ajbspi-57894	108	49	grop	grop	PROPN
ajbspi-57894	108	50	co	co	PROPN
ajbspi-57894	108	51	,	,	PUNCT
ajbspi-57894	108	52	ltd	ltd	PROPN
ajbspi-57894	108	53	general	general	ADJ
ajbspi-57894	108	54	pharm	pharm	NOUN
ajbspi-57894	108	55	factory	factory	NOUN
ajbspi-57894	108	56	150086	150086	NUM
ajbspi-57894	108	57	;	;	PUNCT
ajbspi-57894	108	58	determine	determine	VERB
ajbspi-57894	108	59	the	the	DET
ajbspi-57894	108	60	content	content	NOUN
ajbspi-57894	108	61	of	of	ADP
ajbspi-57894	108	62	cefetamet	cefetamet	ADJ
ajbspi-57894	108	63	pivoxit	pivoxit	NOUN
ajbspi-57894	108	64	hydrochloride	hydrochloride	NOUN
ajbspi-57894	108	65	in	in	ADP
ajbspi-57894	108	66	the	the	DET
ajbspi-57894	108	67	tablet	tablet	NOUN
ajbspi-57894	108	68	of	of	ADP
ajbspi-57894	108	69	cefetamet	cefetamet	ADJ
ajbspi-57894	108	70	pivoxit	pivoxit	NOUN
ajbspi-57894	108	71	hydrochloride	hydrochloride	NOUN
ajbspi-57894	108	72	with	with	ADP
ajbspi-57894	108	73	hplc[j];heilongjiang	hplc[j];heilongjiang	PROPN
ajbspi-57894	108	74	medical	medical	PROPN
ajbspi-57894	108	75	journal;2002	journal;2002	PROPN
ajbspi-57894	108	76	-	-	ADJ
ajbspi-57894	108	77	0	0	NUM
ajbspi-57894	108	78	1	1	NUM
ajbspi-57894	108	79	https://doi.org/10.37547/ajbspi/volume03issue03-01	https://doi.org/10.37547/ajbspi/volume03issue03-01	NOUN
ajbspi-57894	108	80	https://scholar.google.co.in/scholar?q=	https://scholar.google.co.in/scholar?q=	NOUN
ajbspi-57894	108	81	https://www.mendeley.com/search/?page=1&query=	https://www.mendeley.com/search/?page=1&query=	NOUN