id	sid	tid	token	lemma	pos
ajbspi-84390	1	1	american	american	PROPN
ajbspi-84390	1	2	journal	journal	PROPN
ajbspi-84390	1	3	of	of	ADP
ajbspi-84390	1	4	biomedical	biomedical	PROPN
ajbspi-84390	1	5	science	science	PROPN
ajbspi-84390	1	6	&	&	CCONJ
ajbspi-84390	1	7	pharmaceutical	pharmaceutical	NOUN
ajbspi-84390	1	8	innovation	innovation	NOUN
ajbspi-84390	1	9	1	1	NUM
ajbspi-84390	1	10	https://theusajournals.com/index.php/ajbspi	https://theusajournals.com/index.php/ajbspi	NOUN
ajbspi-84390	1	11	volume	volume	NOUN
ajbspi-84390	1	12	vol.05	vol.05	NOUN
ajbspi-84390	1	13	issue04	issue04	NOUN
ajbspi-84390	1	14	2025	2025	NUM
ajbspi-84390	1	15	page	page	NOUN
ajbspi-84390	1	16	no	no	NOUN
ajbspi-84390	1	17	.	.	NOUN
ajbspi-84390	2	1	1	1	NUM
ajbspi-84390	2	2	-	-	SYM
ajbspi-84390	2	3	6	6	NUM
ajbspi-84390	2	4	validated	validated	ADJ
ajbspi-84390	2	5	and	and	CCONJ
ajbspi-84390	2	6	reproducible	reproducible	VERB
ajbspi-84390	2	7	protocol	protocol	NOUN
ajbspi-84390	2	8	for	for	ADP
ajbspi-84390	2	9	culturing	culture	VERB
ajbspi-84390	2	10	singleeye	singleeye	NOUN
ajbspi-84390	2	11	porcine	porcine	NOUN
ajbspi-84390	2	12	retinal	retinal	ADJ
ajbspi-84390	2	13	pigment	pigment	NOUN
ajbspi-84390	2	14	epithelium	epithelium	NOUN
ajbspi-84390	2	15	cells	cell	NOUN
ajbspi-84390	2	16	mason	mason	PROPN
ajbspi-84390	2	17	williams	williams	PROPN
ajbspi-84390	2	18	school	school	PROPN
ajbspi-84390	2	19	of	of	ADP
ajbspi-84390	2	20	clinical	clinical	ADJ
ajbspi-84390	2	21	sciences	science	NOUN
ajbspi-84390	2	22	,	,	PUNCT
ajbspi-84390	2	23	auckland	auckland	PROPN
ajbspi-84390	2	24	university	university	PROPN
ajbspi-84390	2	25	of	of	ADP
ajbspi-84390	2	26	technology	technology	PROPN
ajbspi-84390	2	27	,	,	PUNCT
ajbspi-84390	2	28	northcote	northcote	PROPN
ajbspi-84390	2	29	,	,	PUNCT
ajbspi-84390	2	30	auckland	auckland	PROPN
ajbspi-84390	2	31	,	,	PUNCT
ajbspi-84390	2	32	new	new	PROPN
ajbspi-84390	2	33	zealand	zealand	PROPN
ajbspi-84390	2	34	jacob	jacob	PROPN
ajbspi-84390	2	35	smith	smith	PROPN
ajbspi-84390	2	36	school	school	PROPN
ajbspi-84390	2	37	of	of	ADP
ajbspi-84390	2	38	clinical	clinical	ADJ
ajbspi-84390	2	39	sciences	science	NOUN
ajbspi-84390	2	40	,	,	PUNCT
ajbspi-84390	2	41	auckland	auckland	PROPN
ajbspi-84390	2	42	university	university	PROPN
ajbspi-84390	2	43	of	of	ADP
ajbspi-84390	2	44	technology	technology	PROPN
ajbspi-84390	2	45	,	,	PUNCT
ajbspi-84390	2	46	northcote	northcote	PROPN
ajbspi-84390	2	47	,	,	PUNCT
ajbspi-84390	2	48	auckland	auckland	PROPN
ajbspi-84390	2	49	,	,	PUNCT
ajbspi-84390	2	50	new	new	PROPN
ajbspi-84390	2	51	zealand	zealand	PROPN
ajbspi-84390	2	52	received	receive	VERB
ajbspi-84390	2	53	:	:	PUNCT
ajbspi-84390	2	54	03	03	NUM
ajbspi-84390	2	55	february	february	NOUN
ajbspi-84390	2	56	2025	2025	NUM
ajbspi-84390	2	57	;	;	PUNCT
ajbspi-84390	2	58	accepted	accept	VERB
ajbspi-84390	2	59	:	:	PUNCT
ajbspi-84390	2	60	02	02	NUM
ajbspi-84390	2	61	march	march	NOUN
ajbspi-84390	2	62	2025	2025	NUM
ajbspi-84390	2	63	;	;	PUNCT
ajbspi-84390	2	64	published	publish	VERB
ajbspi-84390	2	65	:	:	PUNCT
ajbspi-84390	2	66	01	01	NUM
ajbspi-84390	2	67	april	april	PROPN
ajbspi-84390	2	68	2025	2025	NUM
ajbspi-84390	2	69	abstract	abstract	NOUN
ajbspi-84390	2	70	:	:	PUNCT
ajbspi-84390	2	71	the	the	DET
ajbspi-84390	2	72	study	study	NOUN
ajbspi-84390	2	73	of	of	ADP
ajbspi-84390	2	74	retinal	retinal	ADJ
ajbspi-84390	2	75	diseases	disease	NOUN
ajbspi-84390	2	76	and	and	CCONJ
ajbspi-84390	2	77	the	the	DET
ajbspi-84390	2	78	development	development	NOUN
ajbspi-84390	2	79	of	of	ADP
ajbspi-84390	2	80	treatments	treatment	NOUN
ajbspi-84390	2	81	for	for	ADP
ajbspi-84390	2	82	conditions	condition	NOUN
ajbspi-84390	2	83	such	such	ADJ
ajbspi-84390	2	84	as	as	ADP
ajbspi-84390	2	85	age	age	NOUN
ajbspi-84390	2	86	-	-	PUNCT
ajbspi-84390	2	87	related	relate	VERB
ajbspi-84390	2	88	macular	macular	ADJ
ajbspi-84390	2	89	degeneration	degeneration	NOUN
ajbspi-84390	2	90	(	(	PUNCT
ajbspi-84390	2	91	amd	amd	NOUN
ajbspi-84390	2	92	)	)	PUNCT
ajbspi-84390	2	93	requires	require	VERB
ajbspi-84390	2	94	reliable	reliable	ADJ
ajbspi-84390	2	95	and	and	CCONJ
ajbspi-84390	2	96	reproducible	reproducible	VERB
ajbspi-84390	2	97	cell	cell	NOUN
ajbspi-84390	2	98	culture	culture	NOUN
ajbspi-84390	2	99	models	model	NOUN
ajbspi-84390	2	100	.	.	PUNCT
ajbspi-84390	3	1	porcine	porcine	VERB
ajbspi-84390	3	2	retinal	retinal	ADJ
ajbspi-84390	3	3	pigment	pigment	NOUN
ajbspi-84390	3	4	epithelium	epithelium	NOUN
ajbspi-84390	3	5	(	(	PUNCT
ajbspi-84390	3	6	rpe	rpe	PROPN
ajbspi-84390	3	7	)	)	PUNCT
ajbspi-84390	3	8	cells	cell	NOUN
ajbspi-84390	3	9	have	have	AUX
ajbspi-84390	3	10	been	be	AUX
ajbspi-84390	3	11	widely	widely	ADV
ajbspi-84390	3	12	used	use	VERB
ajbspi-84390	3	13	due	due	ADP
ajbspi-84390	3	14	to	to	ADP
ajbspi-84390	3	15	their	their	PRON
ajbspi-84390	3	16	similarities	similarity	NOUN
ajbspi-84390	3	17	to	to	ADP
ajbspi-84390	3	18	human	human	ADJ
ajbspi-84390	3	19	rpe	rpe	PROPN
ajbspi-84390	3	20	cells	cell	NOUN
ajbspi-84390	3	21	,	,	PUNCT
ajbspi-84390	3	22	making	make	VERB
ajbspi-84390	3	23	them	they	PRON
ajbspi-84390	3	24	an	an	DET
ajbspi-84390	3	25	ideal	ideal	ADJ
ajbspi-84390	3	26	model	model	NOUN
ajbspi-84390	3	27	for	for	ADP
ajbspi-84390	3	28	retinal	retinal	ADJ
ajbspi-84390	3	29	studies	study	NOUN
ajbspi-84390	3	30	.	.	PUNCT
ajbspi-84390	4	1	however	however	ADV
ajbspi-84390	4	2	,	,	PUNCT
ajbspi-84390	4	3	developing	develop	VERB
ajbspi-84390	4	4	a	a	DET
ajbspi-84390	4	5	standardized	standardized	ADJ
ajbspi-84390	4	6	and	and	CCONJ
ajbspi-84390	4	7	reproducible	reproducible	VERB
ajbspi-84390	4	8	protocol	protocol	NOUN
ajbspi-84390	4	9	for	for	ADP
ajbspi-84390	4	10	culturing	culture	VERB
ajbspi-84390	4	11	these	these	DET
ajbspi-84390	4	12	cells	cell	NOUN
ajbspi-84390	4	13	remains	remain	VERB
ajbspi-84390	4	14	a	a	DET
ajbspi-84390	4	15	challenge	challenge	NOUN
ajbspi-84390	4	16	.	.	PUNCT
ajbspi-84390	5	1	this	this	DET
ajbspi-84390	5	2	article	article	NOUN
ajbspi-84390	5	3	presents	present	VERB
ajbspi-84390	5	4	a	a	DET
ajbspi-84390	5	5	validated	validate	VERB
ajbspi-84390	5	6	protocol	protocol	NOUN
ajbspi-84390	5	7	for	for	ADP
ajbspi-84390	5	8	cultivating	cultivate	VERB
ajbspi-84390	5	9	single	single	ADJ
ajbspi-84390	5	10	-	-	PUNCT
ajbspi-84390	5	11	eye	eye	NOUN
ajbspi-84390	5	12	porcine	porcine	NOUN
ajbspi-84390	5	13	rpe	rpe	PROPN
ajbspi-84390	5	14	cell	cell	NOUN
ajbspi-84390	5	15	cultures	culture	NOUN
ajbspi-84390	5	16	,	,	PUNCT
ajbspi-84390	5	17	ensuring	ensure	VERB
ajbspi-84390	5	18	consistency	consistency	NOUN
ajbspi-84390	5	19	and	and	CCONJ
ajbspi-84390	5	20	reproducibility	reproducibility	NOUN
ajbspi-84390	5	21	across	across	ADP
ajbspi-84390	5	22	experiments	experiment	NOUN
ajbspi-84390	5	23	.	.	PUNCT
ajbspi-84390	6	1	the	the	DET
ajbspi-84390	6	2	protocol	protocol	NOUN
ajbspi-84390	6	3	addresses	address	VERB
ajbspi-84390	6	4	key	key	ADJ
ajbspi-84390	6	5	considerations	consideration	NOUN
ajbspi-84390	6	6	,	,	PUNCT
ajbspi-84390	6	7	including	include	VERB
ajbspi-84390	6	8	tissue	tissue	NOUN
ajbspi-84390	6	9	isolation	isolation	NOUN
ajbspi-84390	6	10	,	,	PUNCT
ajbspi-84390	6	11	cell	cell	NOUN
ajbspi-84390	6	12	maintenance	maintenance	NOUN
ajbspi-84390	6	13	,	,	PUNCT
ajbspi-84390	6	14	and	and	CCONJ
ajbspi-84390	6	15	characterization	characterization	NOUN
ajbspi-84390	6	16	of	of	ADP
ajbspi-84390	6	17	the	the	DET
ajbspi-84390	6	18	cultured	cultured	ADJ
ajbspi-84390	6	19	cells	cell	NOUN
ajbspi-84390	6	20	,	,	PUNCT
ajbspi-84390	6	21	providing	provide	VERB
ajbspi-84390	6	22	a	a	DET
ajbspi-84390	6	23	useful	useful	ADJ
ajbspi-84390	6	24	resource	resource	NOUN
ajbspi-84390	6	25	for	for	ADP
ajbspi-84390	6	26	researchers	researcher	NOUN
ajbspi-84390	6	27	in	in	ADP
ajbspi-84390	6	28	retinal	retinal	ADJ
ajbspi-84390	6	29	biology	biology	NOUN
ajbspi-84390	6	30	and	and	CCONJ
ajbspi-84390	6	31	ophthalmology	ophthalmology	NOUN
ajbspi-84390	6	32	.	.	PUNCT
ajbspi-84390	7	1	keywords	keyword	NOUN
ajbspi-84390	7	2	:	:	PUNCT
ajbspi-84390	7	3	porcine	porcine	NOUN
ajbspi-84390	7	4	rpe	rpe	PROPN
ajbspi-84390	7	5	cells	cell	NOUN
ajbspi-84390	7	6	,	,	PUNCT
ajbspi-84390	7	7	retinal	retinal	ADJ
ajbspi-84390	7	8	pigment	pigment	NOUN
ajbspi-84390	7	9	epithelium	epithelium	NOUN
ajbspi-84390	7	10	,	,	PUNCT
ajbspi-84390	7	11	cell	cell	NOUN
ajbspi-84390	7	12	culture	culture	NOUN
ajbspi-84390	7	13	,	,	PUNCT
ajbspi-84390	7	14	phagocytosis	phagocytosis	NOUN
ajbspi-84390	7	15	,	,	PUNCT
ajbspi-84390	7	16	barrier	barrier	NOUN
ajbspi-84390	7	17	function	function	NOUN
ajbspi-84390	7	18	,	,	PUNCT
ajbspi-84390	7	19	immunocytochemistry	immunocytochemistry	NOUN
ajbspi-84390	7	20	,	,	PUNCT
ajbspi-84390	7	21	retinal	retinal	ADJ
ajbspi-84390	7	22	research	research	NOUN
ajbspi-84390	7	23	,	,	PUNCT
ajbspi-84390	7	24	standardized	standardized	ADJ
ajbspi-84390	7	25	protocol	protocol	NOUN
ajbspi-84390	7	26	,	,	PUNCT
ajbspi-84390	7	27	retinal	retinal	ADJ
ajbspi-84390	7	28	diseases	disease	NOUN
ajbspi-84390	7	29	.	.	PUNCT
ajbspi-84390	8	1	introduction	introduction	NOUN
ajbspi-84390	8	2	:	:	PUNCT
ajbspi-84390	8	3	retinal	retinal	ADJ
ajbspi-84390	8	4	pigment	pigment	NOUN
ajbspi-84390	8	5	epithelium	epithelium	NOUN
ajbspi-84390	8	6	(	(	PUNCT
ajbspi-84390	8	7	rpe	rpe	PROPN
ajbspi-84390	8	8	)	)	PUNCT
ajbspi-84390	8	9	cells	cell	NOUN
ajbspi-84390	8	10	play	play	VERB
ajbspi-84390	8	11	a	a	DET
ajbspi-84390	8	12	crucial	crucial	ADJ
ajbspi-84390	8	13	role	role	NOUN
ajbspi-84390	8	14	in	in	ADP
ajbspi-84390	8	15	the	the	DET
ajbspi-84390	8	16	health	health	NOUN
ajbspi-84390	8	17	and	and	CCONJ
ajbspi-84390	8	18	functionality	functionality	NOUN
ajbspi-84390	8	19	of	of	ADP
ajbspi-84390	8	20	the	the	DET
ajbspi-84390	8	21	retina	retina	NOUN
ajbspi-84390	8	22	.	.	PUNCT
ajbspi-84390	9	1	these	these	DET
ajbspi-84390	9	2	cells	cell	NOUN
ajbspi-84390	9	3	are	be	AUX
ajbspi-84390	9	4	involved	involve	VERB
ajbspi-84390	9	5	in	in	ADP
ajbspi-84390	9	6	several	several	ADJ
ajbspi-84390	9	7	essential	essential	ADJ
ajbspi-84390	9	8	functions	function	NOUN
ajbspi-84390	9	9	,	,	PUNCT
ajbspi-84390	9	10	such	such	ADJ
ajbspi-84390	9	11	as	as	ADP
ajbspi-84390	9	12	phagocytosis	phagocytosis	NOUN
ajbspi-84390	9	13	of	of	ADP
ajbspi-84390	9	14	photoreceptor	photoreceptor	NOUN
ajbspi-84390	9	15	outer	outer	ADJ
ajbspi-84390	9	16	segments	segment	NOUN
ajbspi-84390	9	17	,	,	PUNCT
ajbspi-84390	9	18	secretion	secretion	NOUN
ajbspi-84390	9	19	of	of	ADP
ajbspi-84390	9	20	growth	growth	NOUN
ajbspi-84390	9	21	factors	factor	NOUN
ajbspi-84390	9	22	,	,	PUNCT
ajbspi-84390	9	23	and	and	CCONJ
ajbspi-84390	9	24	maintaining	maintain	VERB
ajbspi-84390	9	25	the	the	DET
ajbspi-84390	9	26	blood	blood	NOUN
ajbspi-84390	9	27	-	-	PUNCT
ajbspi-84390	9	28	retinal	retinal	ADJ
ajbspi-84390	9	29	barrier	barrier	NOUN
ajbspi-84390	9	30	.	.	PUNCT
ajbspi-84390	10	1	defects	defect	NOUN
ajbspi-84390	10	2	in	in	ADP
ajbspi-84390	10	3	rpe	rpe	PROPN
ajbspi-84390	10	4	cell	cell	NOUN
ajbspi-84390	10	5	function	function	NOUN
ajbspi-84390	10	6	are	be	AUX
ajbspi-84390	10	7	implicated	implicate	VERB
ajbspi-84390	10	8	in	in	ADP
ajbspi-84390	10	9	a	a	DET
ajbspi-84390	10	10	variety	variety	NOUN
ajbspi-84390	10	11	of	of	ADP
ajbspi-84390	10	12	retinal	retinal	ADJ
ajbspi-84390	10	13	diseases	disease	NOUN
ajbspi-84390	10	14	,	,	PUNCT
ajbspi-84390	10	15	including	include	VERB
ajbspi-84390	10	16	age	age	NOUN
ajbspi-84390	10	17	-	-	PUNCT
ajbspi-84390	10	18	related	relate	VERB
ajbspi-84390	10	19	macular	macular	ADJ
ajbspi-84390	10	20	degeneration	degeneration	NOUN
ajbspi-84390	10	21	(	(	PUNCT
ajbspi-84390	10	22	amd	amd	ADJ
ajbspi-84390	10	23	)	)	PUNCT
ajbspi-84390	10	24	,	,	PUNCT
ajbspi-84390	10	25	diabetic	diabetic	ADJ
ajbspi-84390	10	26	retinopathy	retinopathy	NOUN
ajbspi-84390	10	27	,	,	PUNCT
ajbspi-84390	10	28	and	and	CCONJ
ajbspi-84390	10	29	retinal	retinal	ADJ
ajbspi-84390	10	30	dystrophies	dystrophy	NOUN
ajbspi-84390	10	31	.	.	PUNCT
ajbspi-84390	11	1	porcine	porcine	NOUN
ajbspi-84390	11	2	rpe	rpe	PROPN
ajbspi-84390	11	3	cells	cell	NOUN
ajbspi-84390	11	4	have	have	AUX
ajbspi-84390	11	5	been	be	AUX
ajbspi-84390	11	6	extensively	extensively	ADV
ajbspi-84390	11	7	used	use	VERB
ajbspi-84390	11	8	as	as	ADP
ajbspi-84390	11	9	an	an	DET
ajbspi-84390	11	10	in	in	ADP
ajbspi-84390	11	11	vitro	vitro	X
ajbspi-84390	11	12	model	model	NOUN
ajbspi-84390	11	13	for	for	ADP
ajbspi-84390	11	14	human	human	ADJ
ajbspi-84390	11	15	retinal	retinal	ADJ
ajbspi-84390	11	16	diseases	disease	NOUN
ajbspi-84390	11	17	due	due	ADP
ajbspi-84390	11	18	to	to	ADP
ajbspi-84390	11	19	their	their	PRON
ajbspi-84390	11	20	anatomical	anatomical	ADJ
ajbspi-84390	11	21	and	and	CCONJ
ajbspi-84390	11	22	functional	functional	ADJ
ajbspi-84390	11	23	similarities	similarity	NOUN
ajbspi-84390	11	24	to	to	ADP
ajbspi-84390	11	25	human	human	PROPN
ajbspi-84390	11	26	rpe	rpe	PROPN
ajbspi-84390	11	27	.	.	PUNCT
ajbspi-84390	12	1	the	the	DET
ajbspi-84390	12	2	use	use	NOUN
ajbspi-84390	12	3	of	of	ADP
ajbspi-84390	12	4	porcine	porcine	NOUN
ajbspi-84390	12	5	models	model	NOUN
ajbspi-84390	12	6	is	be	AUX
ajbspi-84390	12	7	advantageous	advantageous	ADJ
ajbspi-84390	12	8	because	because	SCONJ
ajbspi-84390	12	9	of	of	ADP
ajbspi-84390	12	10	their	their	PRON
ajbspi-84390	12	11	size	size	NOUN
ajbspi-84390	12	12	and	and	CCONJ
ajbspi-84390	12	13	ease	ease	NOUN
ajbspi-84390	12	14	of	of	ADP
ajbspi-84390	12	15	handling	handling	NOUN
ajbspi-84390	12	16	compared	compare	VERB
ajbspi-84390	12	17	to	to	ADP
ajbspi-84390	12	18	other	other	ADJ
ajbspi-84390	12	19	species	specie	NOUN
ajbspi-84390	12	20	,	,	PUNCT
ajbspi-84390	12	21	such	such	ADJ
ajbspi-84390	12	22	as	as	ADP
ajbspi-84390	12	23	primates	primate	NOUN
ajbspi-84390	12	24	.	.	PUNCT
ajbspi-84390	13	1	however	however	ADV
ajbspi-84390	13	2	,	,	PUNCT
ajbspi-84390	13	3	despite	despite	SCONJ
ajbspi-84390	13	4	their	their	PRON
ajbspi-84390	13	5	widespread	widespread	ADJ
ajbspi-84390	13	6	use	use	NOUN
ajbspi-84390	13	7	,	,	PUNCT
ajbspi-84390	13	8	the	the	DET
ajbspi-84390	13	9	lack	lack	NOUN
ajbspi-84390	13	10	of	of	ADP
ajbspi-84390	13	11	standardized	standardized	ADJ
ajbspi-84390	13	12	and	and	CCONJ
ajbspi-84390	13	13	reproducible	reproducible	ADJ
ajbspi-84390	13	14	protocols	protocol	NOUN
ajbspi-84390	13	15	for	for	ADP
ajbspi-84390	13	16	isolating	isolate	VERB
ajbspi-84390	13	17	and	and	CCONJ
ajbspi-84390	13	18	culturing	culture	VERB
ajbspi-84390	13	19	porcine	porcine	NOUN
ajbspi-84390	13	20	rpe	rpe	PROPN
ajbspi-84390	13	21	cells	cell	NOUN
ajbspi-84390	13	22	has	have	AUX
ajbspi-84390	13	23	led	lead	VERB
ajbspi-84390	13	24	to	to	ADP
ajbspi-84390	13	25	inconsistencies	inconsistency	NOUN
ajbspi-84390	13	26	in	in	ADP
ajbspi-84390	13	27	experimental	experimental	ADJ
ajbspi-84390	13	28	results	result	NOUN
ajbspi-84390	13	29	.	.	PUNCT
ajbspi-84390	14	1	the	the	DET
ajbspi-84390	14	2	goal	goal	NOUN
ajbspi-84390	14	3	of	of	ADP
ajbspi-84390	14	4	this	this	DET
ajbspi-84390	14	5	study	study	NOUN
ajbspi-84390	14	6	is	be	AUX
ajbspi-84390	14	7	to	to	PART
ajbspi-84390	14	8	provide	provide	VERB
ajbspi-84390	14	9	a	a	DET
ajbspi-84390	14	10	validated	validate	VERB
ajbspi-84390	14	11	and	and	CCONJ
ajbspi-84390	14	12	reproducible	reproducible	ADJ
ajbspi-84390	14	13	protocol	protocol	NOUN
ajbspi-84390	14	14	for	for	ADP
ajbspi-84390	14	15	culturing	culture	VERB
ajbspi-84390	14	16	single	single	ADJ
ajbspi-84390	14	17	-	-	PUNCT
ajbspi-84390	14	18	eye	eye	NOUN
ajbspi-84390	14	19	porcine	porcine	NOUN
ajbspi-84390	14	20	rpe	rpe	PROPN
ajbspi-84390	14	21	cells	cell	NOUN
ajbspi-84390	14	22	,	,	PUNCT
ajbspi-84390	14	23	focusing	focus	VERB
ajbspi-84390	14	24	on	on	ADP
ajbspi-84390	14	25	tissue	tissue	NOUN
ajbspi-84390	14	26	isolation	isolation	NOUN
ajbspi-84390	14	27	,	,	PUNCT
ajbspi-84390	14	28	cell	cell	NOUN
ajbspi-84390	14	29	culture	culture	NOUN
ajbspi-84390	14	30	conditions	condition	NOUN
ajbspi-84390	14	31	,	,	PUNCT
ajbspi-84390	14	32	and	and	CCONJ
ajbspi-84390	14	33	characterization	characterization	NOUN
ajbspi-84390	14	34	methods	method	NOUN
ajbspi-84390	14	35	.	.	PUNCT
ajbspi-84390	15	1	by	by	ADP
ajbspi-84390	15	2	establishing	establish	VERB
ajbspi-84390	15	3	a	a	DET
ajbspi-84390	15	4	standardized	standardized	ADJ
ajbspi-84390	15	5	protocol	protocol	NOUN
ajbspi-84390	15	6	,	,	PUNCT
ajbspi-84390	15	7	this	this	DET
ajbspi-84390	15	8	study	study	NOUN
ajbspi-84390	15	9	aims	aim	VERB
ajbspi-84390	15	10	to	to	PART
ajbspi-84390	15	11	reduce	reduce	VERB
ajbspi-84390	15	12	variability	variability	NOUN
ajbspi-84390	15	13	between	between	ADP
ajbspi-84390	15	14	experiments	experiment	NOUN
ajbspi-84390	15	15	and	and	CCONJ
ajbspi-84390	15	16	enhance	enhance	VERB
ajbspi-84390	15	17	the	the	DET
ajbspi-84390	15	18	reliability	reliability	NOUN
ajbspi-84390	15	19	of	of	ADP
ajbspi-84390	15	20	porcine	porcine	NOUN
ajbspi-84390	15	21	rpe	rpe	NOUN
ajbspi-84390	15	22	models	model	NOUN
ajbspi-84390	15	23	for	for	ADP
ajbspi-84390	15	24	retinal	retinal	ADJ
ajbspi-84390	15	25	research	research	NOUN
ajbspi-84390	15	26	.	.	PUNCT
ajbspi-84390	16	1	retinal	retinal	ADJ
ajbspi-84390	16	2	diseases	disease	NOUN
ajbspi-84390	16	3	,	,	PUNCT
ajbspi-84390	16	4	particularly	particularly	ADV
ajbspi-84390	16	5	those	those	PRON
ajbspi-84390	16	6	affecting	affect	VERB
ajbspi-84390	16	7	the	the	DET
ajbspi-84390	16	8	retinal	retinal	ADJ
ajbspi-84390	16	9	pigment	pigment	NOUN
ajbspi-84390	16	10	epithelium	epithelium	NOUN
ajbspi-84390	16	11	(	(	PUNCT
ajbspi-84390	16	12	rpe	rpe	PROPN
ajbspi-84390	16	13	)	)	PUNCT
ajbspi-84390	16	14	,	,	PUNCT
ajbspi-84390	16	15	are	be	AUX
ajbspi-84390	16	16	a	a	DET
ajbspi-84390	16	17	significant	significant	ADJ
ajbspi-84390	16	18	cause	cause	NOUN
ajbspi-84390	16	19	of	of	ADP
ajbspi-84390	16	20	visual	visual	ADJ
ajbspi-84390	16	21	impairment	impairment	NOUN
ajbspi-84390	16	22	and	and	CCONJ
ajbspi-84390	16	23	blindness	blindness	NOUN
ajbspi-84390	16	24	worldwide	worldwide	ADV
ajbspi-84390	16	25	.	.	PUNCT
ajbspi-84390	17	1	the	the	DET
ajbspi-84390	17	2	rpe	rpe	PROPN
ajbspi-84390	17	3	is	be	AUX
ajbspi-84390	17	4	a	a	DET
ajbspi-84390	17	5	monolayer	monolayer	NOUN
ajbspi-84390	17	6	of	of	ADP
ajbspi-84390	17	7	specialized	specialized	ADJ
ajbspi-84390	17	8	cells	cell	NOUN
ajbspi-84390	17	9	located	locate	VERB
ajbspi-84390	17	10	between	between	ADP
ajbspi-84390	17	11	the	the	DET
ajbspi-84390	17	12	retina	retina	NOUN
ajbspi-84390	17	13	and	and	CCONJ
ajbspi-84390	17	14	the	the	DET
ajbspi-84390	17	15	choroid	choroid	NOUN
ajbspi-84390	17	16	.	.	PUNCT
ajbspi-84390	18	1	these	these	DET
ajbspi-84390	18	2	cells	cell	NOUN
ajbspi-84390	18	3	play	play	VERB
ajbspi-84390	18	4	a	a	DET
ajbspi-84390	18	5	crucial	crucial	ADJ
ajbspi-84390	18	6	role	role	NOUN
ajbspi-84390	18	7	in	in	ADP
ajbspi-84390	18	8	maintaining	maintain	VERB
ajbspi-84390	18	9	retinal	retinal	ADJ
ajbspi-84390	18	10	homeostasis	homeostasis	NOUN
ajbspi-84390	18	11	by	by	ADP
ajbspi-84390	18	12	performing	perform	VERB
ajbspi-84390	18	13	essential	essential	ADJ
ajbspi-84390	18	14	functions	function	NOUN
ajbspi-84390	18	15	,	,	PUNCT
ajbspi-84390	18	16	such	such	ADJ
ajbspi-84390	18	17	as	as	ADP
ajbspi-84390	18	18	the	the	DET
ajbspi-84390	18	19	phagocytosis	phagocytosis	NOUN
ajbspi-84390	18	20	of	of	ADP
ajbspi-84390	18	21	photoreceptor	photoreceptor	NOUN
ajbspi-84390	18	22	outer	outer	ADJ
ajbspi-84390	18	23	segments	segment	NOUN
ajbspi-84390	18	24	,	,	PUNCT
ajbspi-84390	18	25	secretion	secretion	NOUN
ajbspi-84390	18	26	of	of	ADP
ajbspi-84390	18	27	trophic	trophic	ADJ
ajbspi-84390	18	28	factors	factor	NOUN
ajbspi-84390	18	29	,	,	PUNCT
ajbspi-84390	18	30	absorption	absorption	NOUN
ajbspi-84390	18	31	of	of	ADP
ajbspi-84390	18	32	light	light	NOUN
ajbspi-84390	18	33	,	,	PUNCT
ajbspi-84390	18	34	and	and	CCONJ
ajbspi-84390	18	35	forming	form	VERB
ajbspi-84390	18	36	part	part	NOUN
ajbspi-84390	18	37	of	of	ADP
ajbspi-84390	18	38	the	the	DET
ajbspi-84390	18	39	blood	blood	NOUN
ajbspi-84390	18	40	-	-	PUNCT
ajbspi-84390	18	41	retinal	retinal	ADJ
ajbspi-84390	18	42	barrier	barrier	NOUN
ajbspi-84390	18	43	.	.	PUNCT
ajbspi-84390	19	1	dysfunction	dysfunction	NOUN
ajbspi-84390	19	2	of	of	ADP
ajbspi-84390	19	3	the	the	DET
ajbspi-84390	19	4	rpe	rpe	PROPN
ajbspi-84390	19	5	is	be	AUX
ajbspi-84390	19	6	implicated	implicate	VERB
ajbspi-84390	19	7	in	in	ADP
ajbspi-84390	19	8	a	a	DET
ajbspi-84390	19	9	wide	wide	ADJ
ajbspi-84390	19	10	range	range	NOUN
ajbspi-84390	19	11	of	of	ADP
ajbspi-84390	19	12	retinal	retinal	ADJ
ajbspi-84390	19	13	disorders	disorder	NOUN
ajbspi-84390	19	14	,	,	PUNCT
ajbspi-84390	19	15	including	include	VERB
ajbspi-84390	19	16	age	age	NOUN
ajbspi-84390	19	17	-	-	PUNCT
ajbspi-84390	19	18	related	relate	VERB
ajbspi-84390	19	19	macular	macular	ADJ
ajbspi-84390	19	20	degeneration	degeneration	NOUN
ajbspi-84390	19	21	(	(	PUNCT
ajbspi-84390	19	22	amd	amd	ADJ
ajbspi-84390	19	23	)	)	PUNCT
ajbspi-84390	19	24	,	,	PUNCT
ajbspi-84390	19	25	diabetic	diabetic	ADJ
ajbspi-84390	19	26	retinopathy	retinopathy	NOUN
ajbspi-84390	19	27	,	,	PUNCT
ajbspi-84390	19	28	and	and	CCONJ
ajbspi-84390	19	29	inherited	inherit	VERB
ajbspi-84390	19	30	retinal	retinal	ADJ
ajbspi-84390	19	31	diseases	disease	NOUN
ajbspi-84390	19	32	like	like	ADP
ajbspi-84390	19	33	retinitis	retinitis	NOUN
ajbspi-84390	19	34	pigmentosa	pigmentosa	NOUN
ajbspi-84390	19	35	.	.	PUNCT
ajbspi-84390	20	1	understanding	understand	VERB
ajbspi-84390	20	2	the	the	DET
ajbspi-84390	20	3	biology	biology	NOUN
ajbspi-84390	20	4	of	of	ADP
ajbspi-84390	20	5	rpe	rpe	PROPN
ajbspi-84390	20	6	american	american	PROPN
ajbspi-84390	20	7	journal	journal	PROPN
ajbspi-84390	20	8	of	of	ADP
ajbspi-84390	20	9	applied	apply	VERB
ajbspi-84390	20	10	science	science	NOUN
ajbspi-84390	20	11	and	and	CCONJ
ajbspi-84390	20	12	technology	technology	NOUN
ajbspi-84390	20	13	2	2	NUM
ajbspi-84390	20	14	https://theusajournals.com/index.php/ajast	https://theusajournals.com/index.php/ajast	VERB
ajbspi-84390	20	15	american	american	PROPN
ajbspi-84390	20	16	journal	journal	PROPN
ajbspi-84390	20	17	of	of	ADP
ajbspi-84390	20	18	applied	apply	VERB
ajbspi-84390	20	19	science	science	NOUN
ajbspi-84390	20	20	and	and	CCONJ
ajbspi-84390	20	21	technology	technology	NOUN
ajbspi-84390	20	22	(	(	PUNCT
ajbspi-84390	20	23	issn	issn	PROPN
ajbspi-84390	20	24	:	:	PUNCT
ajbspi-84390	20	25	2771	2771	NUM
ajbspi-84390	20	26	-	-	SYM
ajbspi-84390	20	27	2745	2745	NUM
ajbspi-84390	20	28	)	)	PUNCT
ajbspi-84390	20	29	cells	cell	NOUN
ajbspi-84390	20	30	,	,	PUNCT
ajbspi-84390	20	31	as	as	ADV
ajbspi-84390	20	32	well	well	ADV
ajbspi-84390	20	33	as	as	ADP
ajbspi-84390	20	34	their	their	PRON
ajbspi-84390	20	35	role	role	NOUN
ajbspi-84390	20	36	in	in	ADP
ajbspi-84390	20	37	disease	disease	NOUN
ajbspi-84390	20	38	progression	progression	NOUN
ajbspi-84390	20	39	,	,	PUNCT
ajbspi-84390	20	40	is	be	AUX
ajbspi-84390	20	41	fundamental	fundamental	ADJ
ajbspi-84390	20	42	for	for	ADP
ajbspi-84390	20	43	developing	develop	VERB
ajbspi-84390	20	44	new	new	ADJ
ajbspi-84390	20	45	therapeutic	therapeutic	ADJ
ajbspi-84390	20	46	strategies	strategy	NOUN
ajbspi-84390	20	47	for	for	ADP
ajbspi-84390	20	48	retinal	retinal	ADJ
ajbspi-84390	20	49	diseases	disease	NOUN
ajbspi-84390	20	50	.	.	PUNCT
ajbspi-84390	21	1	to	to	PART
ajbspi-84390	21	2	study	study	VERB
ajbspi-84390	21	3	rpe	rpe	PROPN
ajbspi-84390	21	4	cell	cell	NOUN
ajbspi-84390	21	5	function	function	NOUN
ajbspi-84390	21	6	and	and	CCONJ
ajbspi-84390	21	7	the	the	DET
ajbspi-84390	21	8	mechanisms	mechanism	NOUN
ajbspi-84390	21	9	underlying	underlie	VERB
ajbspi-84390	21	10	retinal	retinal	ADJ
ajbspi-84390	21	11	diseases	disease	NOUN
ajbspi-84390	21	12	,	,	PUNCT
ajbspi-84390	21	13	researchers	researcher	NOUN
ajbspi-84390	21	14	often	often	ADV
ajbspi-84390	21	15	use	use	VERB
ajbspi-84390	21	16	in	in	ADP
ajbspi-84390	21	17	vitro	vitro	X
ajbspi-84390	21	18	cell	cell	NOUN
ajbspi-84390	21	19	culture	culture	NOUN
ajbspi-84390	21	20	models	model	NOUN
ajbspi-84390	21	21	.	.	PUNCT
ajbspi-84390	22	1	the	the	DET
ajbspi-84390	22	2	development	development	NOUN
ajbspi-84390	22	3	of	of	ADP
ajbspi-84390	22	4	reliable	reliable	ADJ
ajbspi-84390	22	5	and	and	CCONJ
ajbspi-84390	22	6	reproducible	reproducible	ADJ
ajbspi-84390	22	7	protocols	protocol	NOUN
ajbspi-84390	22	8	for	for	ADP
ajbspi-84390	22	9	culturing	culture	VERB
ajbspi-84390	22	10	rpe	rpe	PROPN
ajbspi-84390	22	11	cells	cell	NOUN
ajbspi-84390	22	12	is	be	AUX
ajbspi-84390	22	13	essential	essential	ADJ
ajbspi-84390	22	14	for	for	ADP
ajbspi-84390	22	15	obtaining	obtain	VERB
ajbspi-84390	22	16	consistent	consistent	ADJ
ajbspi-84390	22	17	results	result	NOUN
ajbspi-84390	22	18	across	across	ADP
ajbspi-84390	22	19	laboratories	laboratory	NOUN
ajbspi-84390	22	20	and	and	CCONJ
ajbspi-84390	22	21	ensuring	ensure	VERB
ajbspi-84390	22	22	the	the	DET
ajbspi-84390	22	23	reproducibility	reproducibility	NOUN
ajbspi-84390	22	24	of	of	ADP
ajbspi-84390	22	25	experiments	experiment	NOUN
ajbspi-84390	22	26	.	.	PUNCT
ajbspi-84390	23	1	among	among	ADP
ajbspi-84390	23	2	various	various	ADJ
ajbspi-84390	23	3	animal	animal	NOUN
ajbspi-84390	23	4	models	model	NOUN
ajbspi-84390	23	5	,	,	PUNCT
ajbspi-84390	23	6	the	the	DET
ajbspi-84390	23	7	use	use	NOUN
ajbspi-84390	23	8	of	of	ADP
ajbspi-84390	23	9	porcine	porcine	NOUN
ajbspi-84390	23	10	rpe	rpe	PROPN
ajbspi-84390	23	11	cells	cell	NOUN
ajbspi-84390	23	12	is	be	AUX
ajbspi-84390	23	13	particularly	particularly	ADV
ajbspi-84390	23	14	valuable	valuable	ADJ
ajbspi-84390	23	15	due	due	ADP
ajbspi-84390	23	16	to	to	ADP
ajbspi-84390	23	17	their	their	PRON
ajbspi-84390	23	18	close	close	ADJ
ajbspi-84390	23	19	anatomical	anatomical	ADJ
ajbspi-84390	23	20	and	and	CCONJ
ajbspi-84390	23	21	functional	functional	ADJ
ajbspi-84390	23	22	similarity	similarity	NOUN
ajbspi-84390	23	23	to	to	ADP
ajbspi-84390	23	24	human	human	ADJ
ajbspi-84390	23	25	rpe	rpe	PROPN
ajbspi-84390	23	26	cells	cell	NOUN
ajbspi-84390	23	27	.	.	PUNCT
ajbspi-84390	24	1	this	this	PRON
ajbspi-84390	24	2	makes	make	VERB
ajbspi-84390	24	3	porcine	porcine	NOUN
ajbspi-84390	24	4	rpe	rpe	PROPN
ajbspi-84390	24	5	an	an	DET
ajbspi-84390	24	6	excellent	excellent	ADJ
ajbspi-84390	24	7	model	model	NOUN
ajbspi-84390	24	8	for	for	ADP
ajbspi-84390	24	9	studying	study	VERB
ajbspi-84390	24	10	human	human	ADJ
ajbspi-84390	24	11	retinal	retinal	ADJ
ajbspi-84390	24	12	diseases	disease	NOUN
ajbspi-84390	24	13	,	,	PUNCT
ajbspi-84390	24	14	drug	drug	NOUN
ajbspi-84390	24	15	testing	testing	NOUN
ajbspi-84390	24	16	,	,	PUNCT
ajbspi-84390	24	17	and	and	CCONJ
ajbspi-84390	24	18	understanding	understand	VERB
ajbspi-84390	24	19	cellular	cellular	ADJ
ajbspi-84390	24	20	responses	response	NOUN
ajbspi-84390	24	21	to	to	ADP
ajbspi-84390	24	22	treatments	treatment	NOUN
ajbspi-84390	24	23	,	,	PUNCT
ajbspi-84390	24	24	such	such	ADJ
ajbspi-84390	24	25	as	as	ADP
ajbspi-84390	24	26	gene	gene	NOUN
ajbspi-84390	24	27	therapy	therapy	NOUN
ajbspi-84390	24	28	and	and	CCONJ
ajbspi-84390	24	29	stem	stem	VERB
ajbspi-84390	24	30	cell	cell	NOUN
ajbspi-84390	24	31	-	-	PUNCT
ajbspi-84390	24	32	based	base	VERB
ajbspi-84390	24	33	interventions	intervention	NOUN
ajbspi-84390	24	34	.	.	PUNCT
ajbspi-84390	25	1	while	while	SCONJ
ajbspi-84390	25	2	the	the	DET
ajbspi-84390	25	3	porcine	porcine	NOUN
ajbspi-84390	25	4	model	model	NOUN
ajbspi-84390	25	5	offers	offer	VERB
ajbspi-84390	25	6	several	several	ADJ
ajbspi-84390	25	7	advantages	advantage	NOUN
ajbspi-84390	25	8	,	,	PUNCT
ajbspi-84390	25	9	the	the	DET
ajbspi-84390	25	10	isolation	isolation	NOUN
ajbspi-84390	25	11	and	and	CCONJ
ajbspi-84390	25	12	culture	culture	NOUN
ajbspi-84390	25	13	of	of	ADP
ajbspi-84390	25	14	porcine	porcine	NOUN
ajbspi-84390	25	15	rpe	rpe	PROPN
ajbspi-84390	25	16	cells	cell	NOUN
ajbspi-84390	25	17	have	have	AUX
ajbspi-84390	25	18	not	not	PART
ajbspi-84390	25	19	been	be	AUX
ajbspi-84390	25	20	standardized	standardize	VERB
ajbspi-84390	25	21	across	across	ADP
ajbspi-84390	25	22	research	research	NOUN
ajbspi-84390	25	23	laboratories	laboratory	NOUN
ajbspi-84390	25	24	.	.	PUNCT
ajbspi-84390	26	1	variability	variability	NOUN
ajbspi-84390	26	2	in	in	ADP
ajbspi-84390	26	3	culture	culture	NOUN
ajbspi-84390	26	4	conditions	condition	NOUN
ajbspi-84390	26	5	,	,	PUNCT
ajbspi-84390	26	6	tissue	tissue	NOUN
ajbspi-84390	26	7	sources	source	NOUN
ajbspi-84390	26	8	,	,	PUNCT
ajbspi-84390	26	9	and	and	CCONJ
ajbspi-84390	26	10	methodologies	methodology	NOUN
ajbspi-84390	26	11	often	often	ADV
ajbspi-84390	26	12	leads	lead	VERB
ajbspi-84390	26	13	to	to	ADP
ajbspi-84390	26	14	inconsistent	inconsistent	ADJ
ajbspi-84390	26	15	outcomes	outcome	NOUN
ajbspi-84390	26	16	and	and	CCONJ
ajbspi-84390	26	17	limits	limit	VERB
ajbspi-84390	26	18	the	the	DET
ajbspi-84390	26	19	reproducibility	reproducibility	NOUN
ajbspi-84390	26	20	of	of	ADP
ajbspi-84390	26	21	experimental	experimental	ADJ
ajbspi-84390	26	22	results	result	NOUN
ajbspi-84390	26	23	.	.	PUNCT
ajbspi-84390	27	1	the	the	DET
ajbspi-84390	27	2	lack	lack	NOUN
ajbspi-84390	27	3	of	of	ADP
ajbspi-84390	27	4	a	a	DET
ajbspi-84390	27	5	validated	validate	VERB
ajbspi-84390	27	6	,	,	PUNCT
ajbspi-84390	27	7	reproducible	reproducible	ADJ
ajbspi-84390	27	8	protocol	protocol	NOUN
ajbspi-84390	27	9	for	for	ADP
ajbspi-84390	27	10	isolating	isolate	VERB
ajbspi-84390	27	11	and	and	CCONJ
ajbspi-84390	27	12	culturing	culture	VERB
ajbspi-84390	27	13	porcine	porcine	NOUN
ajbspi-84390	27	14	rpe	rpe	PROPN
ajbspi-84390	27	15	cells	cell	NOUN
ajbspi-84390	27	16	further	far	ADV
ajbspi-84390	27	17	complicates	complicate	VERB
ajbspi-84390	27	18	the	the	DET
ajbspi-84390	27	19	comparison	comparison	NOUN
ajbspi-84390	27	20	of	of	ADP
ajbspi-84390	27	21	results	result	NOUN
ajbspi-84390	27	22	between	between	ADP
ajbspi-84390	27	23	studies	study	NOUN
ajbspi-84390	27	24	and	and	CCONJ
ajbspi-84390	27	25	can	can	AUX
ajbspi-84390	27	26	slow	slow	VERB
ajbspi-84390	27	27	progress	progress	NOUN
ajbspi-84390	27	28	in	in	ADP
ajbspi-84390	27	29	retinal	retinal	ADJ
ajbspi-84390	27	30	research	research	NOUN
ajbspi-84390	27	31	.	.	PUNCT
ajbspi-84390	28	1	to	to	PART
ajbspi-84390	28	2	address	address	VERB
ajbspi-84390	28	3	this	this	DET
ajbspi-84390	28	4	gap	gap	NOUN
ajbspi-84390	28	5	,	,	PUNCT
ajbspi-84390	28	6	the	the	DET
ajbspi-84390	28	7	current	current	ADJ
ajbspi-84390	28	8	study	study	NOUN
ajbspi-84390	28	9	presents	present	VERB
ajbspi-84390	28	10	a	a	DET
ajbspi-84390	28	11	validated	validate	VERB
ajbspi-84390	28	12	protocol	protocol	NOUN
ajbspi-84390	28	13	for	for	ADP
ajbspi-84390	28	14	isolating	isolate	VERB
ajbspi-84390	28	15	and	and	CCONJ
ajbspi-84390	28	16	culturing	culture	VERB
ajbspi-84390	28	17	single	single	ADJ
ajbspi-84390	28	18	-	-	PUNCT
ajbspi-84390	28	19	eye	eye	NOUN
ajbspi-84390	28	20	porcine	porcine	NOUN
ajbspi-84390	28	21	rpe	rpe	PROPN
ajbspi-84390	28	22	cells	cell	NOUN
ajbspi-84390	28	23	with	with	ADP
ajbspi-84390	28	24	a	a	DET
ajbspi-84390	28	25	focus	focus	NOUN
ajbspi-84390	28	26	on	on	ADP
ajbspi-84390	28	27	improving	improve	VERB
ajbspi-84390	28	28	reproducibility	reproducibility	NOUN
ajbspi-84390	28	29	and	and	CCONJ
ajbspi-84390	28	30	consistency	consistency	NOUN
ajbspi-84390	28	31	.	.	PUNCT
ajbspi-84390	29	1	the	the	DET
ajbspi-84390	29	2	protocol	protocol	NOUN
ajbspi-84390	29	3	detailed	detail	VERB
ajbspi-84390	29	4	in	in	ADP
ajbspi-84390	29	5	this	this	DET
ajbspi-84390	29	6	article	article	NOUN
ajbspi-84390	29	7	was	be	AUX
ajbspi-84390	29	8	developed	develop	VERB
ajbspi-84390	29	9	to	to	PART
ajbspi-84390	29	10	standardize	standardize	VERB
ajbspi-84390	29	11	several	several	ADJ
ajbspi-84390	29	12	key	key	ADJ
ajbspi-84390	29	13	steps	step	NOUN
ajbspi-84390	29	14	,	,	PUNCT
ajbspi-84390	29	15	such	such	ADJ
ajbspi-84390	29	16	as	as	ADP
ajbspi-84390	29	17	tissue	tissue	NOUN
ajbspi-84390	29	18	dissection	dissection	NOUN
ajbspi-84390	29	19	,	,	PUNCT
ajbspi-84390	29	20	cell	cell	NOUN
ajbspi-84390	29	21	isolation	isolation	NOUN
ajbspi-84390	29	22	,	,	PUNCT
ajbspi-84390	29	23	and	and	CCONJ
ajbspi-84390	29	24	culture	culture	NOUN
ajbspi-84390	29	25	conditions	condition	NOUN
ajbspi-84390	29	26	,	,	PUNCT
ajbspi-84390	29	27	with	with	ADP
ajbspi-84390	29	28	an	an	DET
ajbspi-84390	29	29	emphasis	emphasis	NOUN
ajbspi-84390	29	30	on	on	ADP
ajbspi-84390	29	31	maintaining	maintain	VERB
ajbspi-84390	29	32	cell	cell	NOUN
ajbspi-84390	29	33	viability	viability	NOUN
ajbspi-84390	29	34	,	,	PUNCT
ajbspi-84390	29	35	functionality	functionality	NOUN
ajbspi-84390	29	36	,	,	PUNCT
ajbspi-84390	29	37	and	and	CCONJ
ajbspi-84390	29	38	differentiation	differentiation	NOUN
ajbspi-84390	29	39	.	.	PUNCT
ajbspi-84390	30	1	the	the	DET
ajbspi-84390	30	2	primary	primary	ADJ
ajbspi-84390	30	3	objectives	objective	NOUN
ajbspi-84390	30	4	of	of	ADP
ajbspi-84390	30	5	this	this	DET
ajbspi-84390	30	6	work	work	NOUN
ajbspi-84390	30	7	were	be	AUX
ajbspi-84390	30	8	to	to	PART
ajbspi-84390	30	9	:	:	PUNCT
ajbspi-84390	30	10	1	1	X
ajbspi-84390	30	11	.	.	PUNCT
ajbspi-84390	30	12	establish	establish	VERB
ajbspi-84390	30	13	a	a	DET
ajbspi-84390	30	14	reproducible	reproducible	ADJ
ajbspi-84390	30	15	method	method	NOUN
ajbspi-84390	30	16	for	for	ADP
ajbspi-84390	30	17	isolating	isolate	VERB
ajbspi-84390	30	18	rpe	rpe	PROPN
ajbspi-84390	30	19	cells	cell	NOUN
ajbspi-84390	30	20	from	from	ADP
ajbspi-84390	30	21	porcine	porcine	NOUN
ajbspi-84390	30	22	eyes	eye	NOUN
ajbspi-84390	30	23	.	.	PUNCT
ajbspi-84390	31	1	2	2	X
ajbspi-84390	31	2	.	.	X
ajbspi-84390	31	3	validate	validate	VERB
ajbspi-84390	31	4	culture	culture	NOUN
ajbspi-84390	31	5	conditions	condition	NOUN
ajbspi-84390	31	6	that	that	PRON
ajbspi-84390	31	7	allow	allow	VERB
ajbspi-84390	31	8	for	for	ADP
ajbspi-84390	31	9	optimal	optimal	ADJ
ajbspi-84390	31	10	cell	cell	NOUN
ajbspi-84390	31	11	proliferation	proliferation	NOUN
ajbspi-84390	31	12	and	and	CCONJ
ajbspi-84390	31	13	differentiation	differentiation	NOUN
ajbspi-84390	31	14	into	into	ADP
ajbspi-84390	31	15	functional	functional	ADJ
ajbspi-84390	31	16	rpe	rpe	PROPN
ajbspi-84390	31	17	cells	cell	NOUN
ajbspi-84390	31	18	.	.	PUNCT
ajbspi-84390	32	1	3	3	X
ajbspi-84390	32	2	.	.	X
ajbspi-84390	32	3	characterize	characterize	VERB
ajbspi-84390	32	4	the	the	DET
ajbspi-84390	32	5	isolated	isolate	VERB
ajbspi-84390	32	6	cells	cell	NOUN
ajbspi-84390	32	7	to	to	PART
ajbspi-84390	32	8	confirm	confirm	VERB
ajbspi-84390	32	9	their	their	PRON
ajbspi-84390	32	10	identity	identity	NOUN
ajbspi-84390	32	11	and	and	CCONJ
ajbspi-84390	32	12	functionality	functionality	NOUN
ajbspi-84390	32	13	using	use	VERB
ajbspi-84390	32	14	markers	marker	NOUN
ajbspi-84390	32	15	and	and	CCONJ
ajbspi-84390	32	16	functional	functional	ADJ
ajbspi-84390	32	17	assays	assay	NOUN
ajbspi-84390	32	18	commonly	commonly	ADV
ajbspi-84390	32	19	associated	associate	VERB
ajbspi-84390	32	20	with	with	ADP
ajbspi-84390	32	21	rpe	rpe	PROPN
ajbspi-84390	32	22	cells	cell	NOUN
ajbspi-84390	32	23	.	.	PUNCT
ajbspi-84390	33	1	4	4	X
ajbspi-84390	33	2	.	.	X
ajbspi-84390	33	3	provide	provide	VERB
ajbspi-84390	33	4	a	a	DET
ajbspi-84390	33	5	standardized	standardized	ADJ
ajbspi-84390	33	6	protocol	protocol	NOUN
ajbspi-84390	33	7	that	that	PRON
ajbspi-84390	33	8	can	can	AUX
ajbspi-84390	33	9	be	be	AUX
ajbspi-84390	33	10	readily	readily	ADV
ajbspi-84390	33	11	adopted	adopt	VERB
ajbspi-84390	33	12	by	by	ADP
ajbspi-84390	33	13	other	other	ADJ
ajbspi-84390	33	14	research	research	NOUN
ajbspi-84390	33	15	groups	group	NOUN
ajbspi-84390	33	16	studying	study	VERB
ajbspi-84390	33	17	rpe	rpe	PROPN
ajbspi-84390	33	18	biology	biology	NOUN
ajbspi-84390	33	19	and	and	CCONJ
ajbspi-84390	33	20	retinal	retinal	ADJ
ajbspi-84390	33	21	diseases	disease	NOUN
ajbspi-84390	33	22	.	.	PUNCT
ajbspi-84390	34	1	given	give	VERB
ajbspi-84390	34	2	the	the	DET
ajbspi-84390	34	3	relevance	relevance	NOUN
ajbspi-84390	34	4	of	of	ADP
ajbspi-84390	34	5	rpe	rpe	PROPN
ajbspi-84390	34	6	cells	cell	NOUN
ajbspi-84390	34	7	in	in	ADP
ajbspi-84390	34	8	retinal	retinal	ADJ
ajbspi-84390	34	9	diseases	disease	NOUN
ajbspi-84390	34	10	and	and	CCONJ
ajbspi-84390	34	11	the	the	DET
ajbspi-84390	34	12	increasing	increase	VERB
ajbspi-84390	34	13	need	need	NOUN
ajbspi-84390	34	14	for	for	ADP
ajbspi-84390	34	15	reliable	reliable	ADJ
ajbspi-84390	34	16	in	in	ADP
ajbspi-84390	34	17	vitro	vitro	X
ajbspi-84390	34	18	models	model	NOUN
ajbspi-84390	34	19	to	to	PART
ajbspi-84390	34	20	investigate	investigate	VERB
ajbspi-84390	34	21	these	these	DET
ajbspi-84390	34	22	conditions	condition	NOUN
ajbspi-84390	34	23	,	,	PUNCT
ajbspi-84390	34	24	this	this	DET
ajbspi-84390	34	25	study	study	NOUN
ajbspi-84390	34	26	offers	offer	VERB
ajbspi-84390	34	27	an	an	DET
ajbspi-84390	34	28	essential	essential	ADJ
ajbspi-84390	34	29	resource	resource	NOUN
ajbspi-84390	34	30	for	for	ADP
ajbspi-84390	34	31	the	the	DET
ajbspi-84390	34	32	scientific	scientific	ADJ
ajbspi-84390	34	33	community	community	NOUN
ajbspi-84390	34	34	.	.	PUNCT
ajbspi-84390	35	1	by	by	ADP
ajbspi-84390	35	2	ensuring	ensure	VERB
ajbspi-84390	35	3	consistency	consistency	NOUN
ajbspi-84390	35	4	and	and	CCONJ
ajbspi-84390	35	5	reproducibility	reproducibility	NOUN
ajbspi-84390	35	6	in	in	ADP
ajbspi-84390	35	7	the	the	DET
ajbspi-84390	35	8	cultivation	cultivation	NOUN
ajbspi-84390	35	9	of	of	ADP
ajbspi-84390	35	10	porcine	porcine	NOUN
ajbspi-84390	35	11	rpe	rpe	PROPN
ajbspi-84390	35	12	cells	cell	NOUN
ajbspi-84390	35	13	,	,	PUNCT
ajbspi-84390	35	14	the	the	DET
ajbspi-84390	35	15	protocol	protocol	NOUN
ajbspi-84390	35	16	described	describe	VERB
ajbspi-84390	35	17	here	here	ADV
ajbspi-84390	35	18	will	will	AUX
ajbspi-84390	35	19	facilitate	facilitate	VERB
ajbspi-84390	35	20	more	more	ADV
ajbspi-84390	35	21	accurate	accurate	ADJ
ajbspi-84390	35	22	and	and	CCONJ
ajbspi-84390	35	23	comparable	comparable	ADJ
ajbspi-84390	35	24	results	result	NOUN
ajbspi-84390	35	25	across	across	ADP
ajbspi-84390	35	26	retinal	retinal	ADJ
ajbspi-84390	35	27	research	research	NOUN
ajbspi-84390	35	28	efforts	effort	NOUN
ajbspi-84390	35	29	.	.	PUNCT
ajbspi-84390	36	1	additionally	additionally	ADV
ajbspi-84390	36	2	,	,	PUNCT
ajbspi-84390	36	3	this	this	DET
ajbspi-84390	36	4	work	work	NOUN
ajbspi-84390	36	5	may	may	AUX
ajbspi-84390	36	6	contribute	contribute	VERB
ajbspi-84390	36	7	to	to	ADP
ajbspi-84390	36	8	the	the	DET
ajbspi-84390	36	9	development	development	NOUN
ajbspi-84390	36	10	of	of	ADP
ajbspi-84390	36	11	new	new	ADJ
ajbspi-84390	36	12	treatments	treatment	NOUN
ajbspi-84390	36	13	for	for	ADP
ajbspi-84390	36	14	retinal	retinal	ADJ
ajbspi-84390	36	15	diseases	disease	NOUN
ajbspi-84390	36	16	,	,	PUNCT
ajbspi-84390	36	17	such	such	ADJ
ajbspi-84390	36	18	as	as	ADP
ajbspi-84390	36	19	gene	gene	NOUN
ajbspi-84390	36	20	therapy	therapy	NOUN
ajbspi-84390	36	21	,	,	PUNCT
ajbspi-84390	36	22	stem	stem	VERB
ajbspi-84390	36	23	cell	cell	NOUN
ajbspi-84390	36	24	-	-	PUNCT
ajbspi-84390	36	25	based	base	VERB
ajbspi-84390	36	26	therapies	therapy	NOUN
ajbspi-84390	36	27	,	,	PUNCT
ajbspi-84390	36	28	and	and	CCONJ
ajbspi-84390	36	29	pharmacological	pharmacological	ADJ
ajbspi-84390	36	30	interventions	intervention	NOUN
ajbspi-84390	36	31	.	.	PUNCT
ajbspi-84390	37	1	in	in	ADP
ajbspi-84390	37	2	the	the	DET
ajbspi-84390	37	3	following	follow	VERB
ajbspi-84390	37	4	sections	section	NOUN
ajbspi-84390	37	5	,	,	PUNCT
ajbspi-84390	37	6	we	we	PRON
ajbspi-84390	37	7	present	present	VERB
ajbspi-84390	37	8	the	the	DET
ajbspi-84390	37	9	materials	material	NOUN
ajbspi-84390	37	10	and	and	CCONJ
ajbspi-84390	37	11	methods	method	NOUN
ajbspi-84390	37	12	used	use	VERB
ajbspi-84390	37	13	to	to	PART
ajbspi-84390	37	14	isolate	isolate	VERB
ajbspi-84390	37	15	and	and	CCONJ
ajbspi-84390	37	16	culture	culture	VERB
ajbspi-84390	37	17	the	the	DET
ajbspi-84390	37	18	single	single	ADJ
ajbspi-84390	37	19	-	-	PUNCT
ajbspi-84390	37	20	eye	eye	NOUN
ajbspi-84390	37	21	porcine	porcine	NOUN
ajbspi-84390	37	22	rpe	rpe	PROPN
ajbspi-84390	37	23	cells	cell	NOUN
ajbspi-84390	37	24	,	,	PUNCT
ajbspi-84390	37	25	followed	follow	VERB
ajbspi-84390	37	26	by	by	ADP
ajbspi-84390	37	27	results	result	NOUN
ajbspi-84390	37	28	that	that	PRON
ajbspi-84390	37	29	demonstrate	demonstrate	VERB
ajbspi-84390	37	30	the	the	DET
ajbspi-84390	37	31	effectiveness	effectiveness	NOUN
ajbspi-84390	37	32	of	of	ADP
ajbspi-84390	37	33	this	this	DET
ajbspi-84390	37	34	protocol	protocol	NOUN
ajbspi-84390	37	35	in	in	ADP
ajbspi-84390	37	36	producing	produce	VERB
ajbspi-84390	37	37	functional	functional	ADJ
ajbspi-84390	37	38	and	and	CCONJ
ajbspi-84390	37	39	reproducible	reproducible	VERB
ajbspi-84390	37	40	rpe	rpe	PROPN
ajbspi-84390	37	41	cell	cell	NOUN
ajbspi-84390	37	42	cultures	culture	NOUN
ajbspi-84390	37	43	.	.	PUNCT
ajbspi-84390	38	1	methods	method	NOUN
ajbspi-84390	38	2	1	1	NUM
ajbspi-84390	38	3	.	.	PUNCT
ajbspi-84390	38	4	isolation	isolation	NOUN
ajbspi-84390	38	5	of	of	ADP
ajbspi-84390	38	6	porcine	porcine	ADJ
ajbspi-84390	38	7	retinal	retinal	ADJ
ajbspi-84390	38	8	tissue	tissue	NOUN
ajbspi-84390	38	9	porcine	porcine	NOUN
ajbspi-84390	38	10	eyes	eye	NOUN
ajbspi-84390	38	11	were	be	AUX
ajbspi-84390	38	12	obtained	obtain	VERB
ajbspi-84390	38	13	from	from	ADP
ajbspi-84390	38	14	a	a	DET
ajbspi-84390	38	15	local	local	ADJ
ajbspi-84390	38	16	abattoir	abattoir	NOUN
ajbspi-84390	38	17	within	within	ADP
ajbspi-84390	38	18	two	two	NUM
ajbspi-84390	38	19	hours	hour	NOUN
ajbspi-84390	38	20	post	post	ADJ
ajbspi-84390	38	21	-	-	ADJ
ajbspi-84390	38	22	mortem	mortem	ADJ
ajbspi-84390	38	23	.	.	PUNCT
ajbspi-84390	39	1	each	each	DET
ajbspi-84390	39	2	eye	eye	NOUN
ajbspi-84390	39	3	was	be	AUX
ajbspi-84390	39	4	carefully	carefully	ADV
ajbspi-84390	39	5	dissected	dissect	VERB
ajbspi-84390	39	6	,	,	PUNCT
ajbspi-84390	39	7	and	and	CCONJ
ajbspi-84390	39	8	the	the	DET
ajbspi-84390	39	9	retina	retina	NOUN
ajbspi-84390	39	10	was	be	AUX
ajbspi-84390	39	11	separated	separate	VERB
ajbspi-84390	39	12	from	from	ADP
ajbspi-84390	39	13	the	the	DET
ajbspi-84390	39	14	underlying	underlie	VERB
ajbspi-84390	39	15	choroid	choroid	NOUN
ajbspi-84390	39	16	by	by	ADP
ajbspi-84390	39	17	gentle	gentle	ADJ
ajbspi-84390	39	18	mechanical	mechanical	ADJ
ajbspi-84390	39	19	dissection	dissection	NOUN
ajbspi-84390	39	20	under	under	ADP
ajbspi-84390	39	21	sterile	sterile	ADJ
ajbspi-84390	39	22	conditions	condition	NOUN
ajbspi-84390	39	23	.	.	PUNCT
ajbspi-84390	40	1	the	the	DET
ajbspi-84390	40	2	retinal	retinal	ADJ
ajbspi-84390	40	3	pigment	pigment	NOUN
ajbspi-84390	40	4	epithelium	epithelium	NOUN
ajbspi-84390	40	5	(	(	PUNCT
ajbspi-84390	40	6	rpe	rpe	PROPN
ajbspi-84390	40	7	)	)	PUNCT
ajbspi-84390	40	8	layer	layer	NOUN
ajbspi-84390	40	9	was	be	AUX
ajbspi-84390	40	10	isolated	isolate	VERB
ajbspi-84390	40	11	from	from	ADP
ajbspi-84390	40	12	the	the	DET
ajbspi-84390	40	13	retina	retina	NOUN
ajbspi-84390	40	14	using	use	VERB
ajbspi-84390	40	15	a	a	DET
ajbspi-84390	40	16	blunt	blunt	ADJ
ajbspi-84390	40	17	scraping	scraping	NOUN
ajbspi-84390	40	18	technique	technique	NOUN
ajbspi-84390	40	19	.	.	PUNCT
ajbspi-84390	41	1	the	the	DET
ajbspi-84390	41	2	isolated	isolate	VERB
ajbspi-84390	41	3	rpe	rpe	PROPN
ajbspi-84390	41	4	sheet	sheet	NOUN
ajbspi-84390	41	5	was	be	AUX
ajbspi-84390	41	6	transferred	transfer	VERB
ajbspi-84390	41	7	to	to	ADP
ajbspi-84390	41	8	a	a	DET
ajbspi-84390	41	9	sterile	sterile	ADJ
ajbspi-84390	41	10	petri	petri	ADJ
ajbspi-84390	41	11	dish	dish	NOUN
ajbspi-84390	41	12	containing	contain	VERB
ajbspi-84390	41	13	rpe	rpe	PROPN
ajbspi-84390	41	14	culture	culture	NOUN
ajbspi-84390	41	15	medium	medium	NOUN
ajbspi-84390	41	16	for	for	ADP
ajbspi-84390	41	17	further	further	ADJ
ajbspi-84390	41	18	processing	processing	NOUN
ajbspi-84390	41	19	.	.	PUNCT
ajbspi-84390	42	1	2	2	X
ajbspi-84390	42	2	.	.	X
ajbspi-84390	42	3	cell	cell	NOUN
ajbspi-84390	42	4	culture	culture	NOUN
ajbspi-84390	42	5	conditions	condition	NOUN
ajbspi-84390	42	6	after	after	SCONJ
ajbspi-84390	42	7	the	the	DET
ajbspi-84390	42	8	rpe	rpe	PROPN
ajbspi-84390	42	9	layer	layer	NOUN
ajbspi-84390	42	10	was	be	AUX
ajbspi-84390	42	11	separated	separate	VERB
ajbspi-84390	42	12	,	,	PUNCT
ajbspi-84390	42	13	it	it	PRON
ajbspi-84390	42	14	was	be	AUX
ajbspi-84390	42	15	minced	mince	VERB
ajbspi-84390	42	16	into	into	ADP
ajbspi-84390	42	17	small	small	ADJ
ajbspi-84390	42	18	pieces	piece	NOUN
ajbspi-84390	42	19	,	,	PUNCT
ajbspi-84390	42	20	and	and	CCONJ
ajbspi-84390	42	21	the	the	DET
ajbspi-84390	42	22	tissue	tissue	NOUN
ajbspi-84390	42	23	was	be	AUX
ajbspi-84390	42	24	enzymatically	enzymatically	ADV
ajbspi-84390	42	25	dissociated	dissociate	VERB
ajbspi-84390	42	26	with	with	ADP
ajbspi-84390	42	27	a	a	DET
ajbspi-84390	42	28	0.25	0.25	NUM
ajbspi-84390	42	29	%	%	NOUN
ajbspi-84390	42	30	trypsin	trypsin	NOUN
ajbspi-84390	42	31	solution	solution	NOUN
ajbspi-84390	42	32	for	for	ADP
ajbspi-84390	42	33	30	30	NUM
ajbspi-84390	42	34	minutes	minute	NOUN
ajbspi-84390	42	35	at	at	ADP
ajbspi-84390	42	36	37	37	NUM
ajbspi-84390	42	37	°	°	NOUN
ajbspi-84390	42	38	c	c	NOUN
ajbspi-84390	42	39	.	.	PUNCT
ajbspi-84390	43	1	the	the	DET
ajbspi-84390	43	2	dissociation	dissociation	NOUN
ajbspi-84390	43	3	process	process	NOUN
ajbspi-84390	43	4	was	be	AUX
ajbspi-84390	43	5	carefully	carefully	ADV
ajbspi-84390	43	6	monitored	monitor	VERB
ajbspi-84390	43	7	under	under	ADP
ajbspi-84390	43	8	a	a	DET
ajbspi-84390	43	9	microscope	microscope	NOUN
ajbspi-84390	43	10	to	to	PART
ajbspi-84390	43	11	prevent	prevent	VERB
ajbspi-84390	43	12	overdigestion	overdigestion	NOUN
ajbspi-84390	43	13	.	.	PUNCT
ajbspi-84390	44	1	following	follow	VERB
ajbspi-84390	44	2	enzymatic	enzymatic	ADJ
ajbspi-84390	44	3	digestion	digestion	NOUN
ajbspi-84390	44	4	,	,	PUNCT
ajbspi-84390	44	5	the	the	DET
ajbspi-84390	44	6	cell	cell	NOUN
ajbspi-84390	44	7	suspension	suspension	NOUN
ajbspi-84390	44	8	was	be	AUX
ajbspi-84390	44	9	filtered	filter	VERB
ajbspi-84390	44	10	through	through	ADP
ajbspi-84390	44	11	a	a	DET
ajbspi-84390	44	12	70	70	NUM
ajbspi-84390	44	13	µm	µm	NOUN
ajbspi-84390	44	14	cell	cell	NOUN
ajbspi-84390	44	15	strainer	strainer	NOUN
ajbspi-84390	44	16	to	to	PART
ajbspi-84390	44	17	remove	remove	VERB
ajbspi-84390	44	18	clumps	clump	NOUN
ajbspi-84390	44	19	.	.	PUNCT
ajbspi-84390	45	1	cells	cell	NOUN
ajbspi-84390	45	2	were	be	AUX
ajbspi-84390	45	3	plated	plate	VERB
ajbspi-84390	45	4	in	in	ADP
ajbspi-84390	45	5	six	six	NUM
ajbspi-84390	45	6	-	-	PUNCT
ajbspi-84390	45	7	well	well	NOUN
ajbspi-84390	45	8	culture	culture	NOUN
ajbspi-84390	45	9	plates	plate	NOUN
ajbspi-84390	45	10	at	at	ADP
ajbspi-84390	45	11	a	a	DET
ajbspi-84390	45	12	density	density	NOUN
ajbspi-84390	45	13	of	of	ADP
ajbspi-84390	45	14	1×10	1×10	NUM
ajbspi-84390	45	15	^	^	SYM
ajbspi-84390	45	16	5	5	NUM
ajbspi-84390	45	17	cells	cell	NOUN
ajbspi-84390	45	18	/	/	SYM
ajbspi-84390	45	19	well	well	ADV
ajbspi-84390	45	20	in	in	ADP
ajbspi-84390	45	21	a	a	DET
ajbspi-84390	45	22	complete	complete	ADJ
ajbspi-84390	45	23	rpe	rpe	PROPN
ajbspi-84390	45	24	culture	culture	NOUN
ajbspi-84390	45	25	medium	medium	NOUN
ajbspi-84390	45	26	consisting	consist	VERB
ajbspi-84390	45	27	of	of	ADP
ajbspi-84390	45	28	dulbecco	dulbecco	NOUN
ajbspi-84390	45	29	’s	’s	PART
ajbspi-84390	45	30	modified	modify	VERB
ajbspi-84390	45	31	eagle	eagle	PROPN
ajbspi-84390	45	32	medium	medium	NOUN
ajbspi-84390	45	33	(	(	PUNCT
ajbspi-84390	45	34	dmem	dmem	ADJ
ajbspi-84390	45	35	)	)	PUNCT
ajbspi-84390	45	36	,	,	PUNCT
ajbspi-84390	45	37	fetal	fetal	ADJ
ajbspi-84390	45	38	bovine	bovine	NOUN
ajbspi-84390	45	39	serum	serum	NOUN
ajbspi-84390	45	40	(	(	PUNCT
ajbspi-84390	45	41	fbs	fbs	PROPN
ajbspi-84390	45	42	)	)	PUNCT
ajbspi-84390	45	43	,	,	PUNCT
ajbspi-84390	45	44	and	and	CCONJ
ajbspi-84390	45	45	a	a	DET
ajbspi-84390	45	46	mixture	mixture	NOUN
ajbspi-84390	45	47	of	of	ADP
ajbspi-84390	45	48	antibiotics	antibiotic	NOUN
ajbspi-84390	45	49	.	.	PUNCT
ajbspi-84390	46	1	the	the	DET
ajbspi-84390	46	2	culture	culture	NOUN
ajbspi-84390	46	3	medium	medium	NOUN
ajbspi-84390	46	4	was	be	AUX
ajbspi-84390	46	5	changed	change	VERB
ajbspi-84390	46	6	every	every	DET
ajbspi-84390	46	7	2	2	NUM
ajbspi-84390	46	8	-	-	SYM
ajbspi-84390	46	9	3	3	NUM
ajbspi-84390	46	10	days	day	NOUN
ajbspi-84390	46	11	,	,	PUNCT
ajbspi-84390	46	12	and	and	CCONJ
ajbspi-84390	46	13	cells	cell	NOUN
ajbspi-84390	46	14	were	be	AUX
ajbspi-84390	46	15	maintained	maintain	VERB
ajbspi-84390	46	16	in	in	ADP
ajbspi-84390	46	17	a	a	DET
ajbspi-84390	46	18	humidified	humidify	VERB
ajbspi-84390	46	19	incubator	incubator	NOUN
ajbspi-84390	46	20	at	at	ADP
ajbspi-84390	46	21	37	37	NUM
ajbspi-84390	46	22	°	°	ADP
ajbspi-84390	46	23	c	c	NOUN
ajbspi-84390	46	24	with	with	ADP
ajbspi-84390	46	25	5	5	NUM
ajbspi-84390	46	26	%	%	NOUN
ajbspi-84390	46	27	co2	co2	NOUN
ajbspi-84390	46	28	.	.	PUNCT
ajbspi-84390	47	1	the	the	DET
ajbspi-84390	47	2	cells	cell	NOUN
ajbspi-84390	47	3	were	be	AUX
ajbspi-84390	47	4	allowed	allow	VERB
ajbspi-84390	47	5	to	to	PART
ajbspi-84390	47	6	proliferate	proliferate	VERB
ajbspi-84390	47	7	for	for	ADP
ajbspi-84390	47	8	up	up	ADP
ajbspi-84390	47	9	to	to	PART
ajbspi-84390	47	10	7	7	NUM
ajbspi-84390	47	11	-	-	SYM
ajbspi-84390	47	12	10	10	NUM
ajbspi-84390	47	13	days	day	NOUN
ajbspi-84390	47	14	before	before	ADP
ajbspi-84390	47	15	being	be	AUX
ajbspi-84390	47	16	used	use	VERB
ajbspi-84390	47	17	for	for	ADP
ajbspi-84390	47	18	downstream	downstream	ADJ
ajbspi-84390	47	19	experiments	experiment	NOUN
ajbspi-84390	47	20	.	.	PUNCT
ajbspi-84390	48	1	3	3	X
ajbspi-84390	48	2	.	.	X
ajbspi-84390	48	3	characterization	characterization	NOUN
ajbspi-84390	48	4	of	of	ADP
ajbspi-84390	48	5	cultured	cultured	ADJ
ajbspi-84390	48	6	rpe	rpe	PROPN
ajbspi-84390	48	7	cells	cell	NOUN
ajbspi-84390	48	8	to	to	PART
ajbspi-84390	48	9	confirm	confirm	VERB
ajbspi-84390	48	10	the	the	DET
ajbspi-84390	48	11	successful	successful	ADJ
ajbspi-84390	48	12	isolation	isolation	NOUN
ajbspi-84390	48	13	and	and	CCONJ
ajbspi-84390	48	14	culture	culture	NOUN
ajbspi-84390	48	15	of	of	ADP
ajbspi-84390	48	16	porcine	porcine	NOUN
ajbspi-84390	48	17	rpe	rpe	PROPN
ajbspi-84390	48	18	cells	cell	NOUN
ajbspi-84390	48	19	,	,	PUNCT
ajbspi-84390	48	20	several	several	ADJ
ajbspi-84390	48	21	characterization	characterization	NOUN
ajbspi-84390	48	22	techniques	technique	NOUN
ajbspi-84390	48	23	were	be	AUX
ajbspi-84390	48	24	employed	employ	VERB
ajbspi-84390	48	25	.	.	PUNCT
ajbspi-84390	49	1	first	first	ADV
ajbspi-84390	49	2	,	,	PUNCT
ajbspi-84390	49	3	the	the	DET
ajbspi-84390	49	4	cells	cell	NOUN
ajbspi-84390	49	5	were	be	AUX
ajbspi-84390	49	6	assessed	assess	VERB
ajbspi-84390	49	7	for	for	ADP
ajbspi-84390	49	8	the	the	DET
ajbspi-84390	49	9	expression	expression	NOUN
ajbspi-84390	49	10	of	of	ADP
ajbspi-84390	49	11	rpe	rpe	PROPN
ajbspi-84390	49	12	-	-	PUNCT
ajbspi-84390	49	13	specific	specific	ADJ
ajbspi-84390	49	14	markers	marker	NOUN
ajbspi-84390	49	15	,	,	PUNCT
ajbspi-84390	49	16	including	include	VERB
ajbspi-84390	49	17	bestrophin	bestrophin	PROPN
ajbspi-84390	49	18	,	,	PUNCT
ajbspi-84390	49	19	pax6	pax6	NOUN
ajbspi-84390	49	20	,	,	PUNCT
ajbspi-84390	49	21	and	and	CCONJ
ajbspi-84390	49	22	zo-1	zo-1	NUM
ajbspi-84390	49	23	,	,	PUNCT
ajbspi-84390	49	24	through	through	ADP
ajbspi-84390	49	25	immunocytochemistry	immunocytochemistry	NOUN
ajbspi-84390	49	26	.	.	PUNCT
ajbspi-84390	50	1	additionally	additionally	ADV
ajbspi-84390	50	2	,	,	PUNCT
ajbspi-84390	50	3	the	the	DET
ajbspi-84390	50	4	morphology	morphology	NOUN
ajbspi-84390	50	5	of	of	ADP
ajbspi-84390	50	6	the	the	DET
ajbspi-84390	50	7	cells	cell	NOUN
ajbspi-84390	50	8	was	be	AUX
ajbspi-84390	50	9	observed	observe	VERB
ajbspi-84390	50	10	under	under	ADP
ajbspi-84390	50	11	phase	phase	NOUN
ajbspi-84390	50	12	-	-	PUNCT
ajbspi-84390	50	13	contrast	contrast	NOUN
ajbspi-84390	50	14	microscopy	microscopy	NOUN
ajbspi-84390	50	15	,	,	PUNCT
ajbspi-84390	50	16	and	and	CCONJ
ajbspi-84390	50	17	confluence	confluence	NOUN
ajbspi-84390	50	18	was	be	AUX
ajbspi-84390	50	19	monitored	monitor	VERB
ajbspi-84390	50	20	over	over	ADP
ajbspi-84390	50	21	the	the	DET
ajbspi-84390	50	22	culture	culture	NOUN
ajbspi-84390	50	23	period	period	NOUN
ajbspi-84390	50	24	.	.	PUNCT
ajbspi-84390	51	1	the	the	DET
ajbspi-84390	51	2	functional	functional	ADJ
ajbspi-84390	51	3	integrity	integrity	NOUN
ajbspi-84390	51	4	of	of	ADP
ajbspi-84390	51	5	the	the	DET
ajbspi-84390	51	6	rpe	rpe	PROPN
ajbspi-84390	51	7	cells	cell	NOUN
ajbspi-84390	51	8	was	be	AUX
ajbspi-84390	51	9	assessed	assess	VERB
ajbspi-84390	51	10	by	by	ADP
ajbspi-84390	51	11	measuring	measure	VERB
ajbspi-84390	51	12	transepithelial	transepithelial	ADJ
ajbspi-84390	51	13	resistance	resistance	NOUN
ajbspi-84390	51	14	(	(	PUNCT
ajbspi-84390	51	15	ter	ter	NOUN
ajbspi-84390	51	16	)	)	PUNCT
ajbspi-84390	51	17	across	across	ADP
ajbspi-84390	51	18	american	american	PROPN
ajbspi-84390	51	19	journal	journal	PROPN
ajbspi-84390	51	20	of	of	ADP
ajbspi-84390	51	21	applied	apply	VERB
ajbspi-84390	51	22	science	science	NOUN
ajbspi-84390	51	23	and	and	CCONJ
ajbspi-84390	51	24	technology	technology	NOUN
ajbspi-84390	51	25	3	3	NUM
ajbspi-84390	51	26	https://theusajournals.com/index.php/ajast	https://theusajournals.com/index.php/ajast	VERB
ajbspi-84390	51	27	american	american	PROPN
ajbspi-84390	51	28	journal	journal	PROPN
ajbspi-84390	51	29	of	of	ADP
ajbspi-84390	51	30	applied	apply	VERB
ajbspi-84390	51	31	science	science	NOUN
ajbspi-84390	51	32	and	and	CCONJ
ajbspi-84390	51	33	technology	technology	NOUN
ajbspi-84390	51	34	(	(	PUNCT
ajbspi-84390	51	35	issn	issn	PROPN
ajbspi-84390	51	36	:	:	PUNCT
ajbspi-84390	51	37	2771	2771	NUM
ajbspi-84390	51	38	-	-	SYM
ajbspi-84390	51	39	2745	2745	NUM
ajbspi-84390	51	40	)	)	PUNCT
ajbspi-84390	51	41	the	the	DET
ajbspi-84390	51	42	monolayer	monolayer	NOUN
ajbspi-84390	51	43	,	,	PUNCT
ajbspi-84390	51	44	which	which	PRON
ajbspi-84390	51	45	reflects	reflect	VERB
ajbspi-84390	51	46	the	the	DET
ajbspi-84390	51	47	barrier	barrier	NOUN
ajbspi-84390	51	48	function	function	NOUN
ajbspi-84390	51	49	of	of	ADP
ajbspi-84390	51	50	the	the	DET
ajbspi-84390	51	51	rpe	rpe	PROPN
ajbspi-84390	51	52	.	.	PUNCT
ajbspi-84390	52	1	higher	high	ADJ
ajbspi-84390	52	2	ter	ter	NOUN
ajbspi-84390	52	3	values	value	NOUN
ajbspi-84390	52	4	indicate	indicate	VERB
ajbspi-84390	52	5	healthy	healthy	ADJ
ajbspi-84390	52	6	,	,	PUNCT
ajbspi-84390	52	7	differentiated	differentiated	ADJ
ajbspi-84390	52	8	rpe	rpe	PROPN
ajbspi-84390	52	9	cells	cell	NOUN
ajbspi-84390	52	10	with	with	ADP
ajbspi-84390	52	11	intact	intact	ADJ
ajbspi-84390	52	12	junctional	junctional	ADJ
ajbspi-84390	52	13	complexes	complex	NOUN
ajbspi-84390	52	14	.	.	PUNCT
ajbspi-84390	53	1	further	far	ADV
ajbspi-84390	53	2	,	,	PUNCT
ajbspi-84390	53	3	phagocytosis	phagocytosis	NOUN
ajbspi-84390	53	4	assays	assay	NOUN
ajbspi-84390	53	5	were	be	AUX
ajbspi-84390	53	6	conducted	conduct	VERB
ajbspi-84390	53	7	to	to	PART
ajbspi-84390	53	8	evaluate	evaluate	VERB
ajbspi-84390	53	9	the	the	DET
ajbspi-84390	53	10	cells	cell	NOUN
ajbspi-84390	53	11	'	'	PART
ajbspi-84390	53	12	ability	ability	NOUN
ajbspi-84390	53	13	to	to	PART
ajbspi-84390	53	14	ingest	ingest	VERB
ajbspi-84390	53	15	and	and	CCONJ
ajbspi-84390	53	16	process	process	VERB
ajbspi-84390	53	17	photoreceptor	photoreceptor	NOUN
ajbspi-84390	53	18	outer	outer	ADJ
ajbspi-84390	53	19	segment	segment	NOUN
ajbspi-84390	53	20	-	-	PUNCT
ajbspi-84390	53	21	like	like	ADJ
ajbspi-84390	53	22	particles	particle	NOUN
ajbspi-84390	53	23	,	,	PUNCT
ajbspi-84390	53	24	a	a	DET
ajbspi-84390	53	25	key	key	ADJ
ajbspi-84390	53	26	function	function	NOUN
ajbspi-84390	53	27	of	of	ADP
ajbspi-84390	53	28	rpe	rpe	PROPN
ajbspi-84390	53	29	cells	cell	NOUN
ajbspi-84390	53	30	.	.	PUNCT
ajbspi-84390	54	1	4	4	X
ajbspi-84390	54	2	.	.	X
ajbspi-84390	54	3	statistical	statistical	ADJ
ajbspi-84390	54	4	analysis	analysis	NOUN
ajbspi-84390	54	5	all	all	DET
ajbspi-84390	54	6	experiments	experiment	NOUN
ajbspi-84390	54	7	were	be	AUX
ajbspi-84390	54	8	conducted	conduct	VERB
ajbspi-84390	54	9	in	in	ADP
ajbspi-84390	54	10	triplicate	triplicate	NOUN
ajbspi-84390	54	11	,	,	PUNCT
ajbspi-84390	54	12	and	and	CCONJ
ajbspi-84390	54	13	data	datum	NOUN
ajbspi-84390	54	14	are	be	AUX
ajbspi-84390	54	15	presented	present	VERB
ajbspi-84390	54	16	as	as	ADP
ajbspi-84390	54	17	mean	mean	NOUN
ajbspi-84390	54	18	±	±	NUM
ajbspi-84390	54	19	standard	standard	ADJ
ajbspi-84390	54	20	deviation	deviation	NOUN
ajbspi-84390	54	21	.	.	PUNCT
ajbspi-84390	55	1	statistical	statistical	ADJ
ajbspi-84390	55	2	significance	significance	NOUN
ajbspi-84390	55	3	was	be	AUX
ajbspi-84390	55	4	determined	determine	VERB
ajbspi-84390	55	5	using	use	VERB
ajbspi-84390	55	6	a	a	DET
ajbspi-84390	55	7	one	one	NUM
ajbspi-84390	55	8	-	-	PUNCT
ajbspi-84390	55	9	way	way	NOUN
ajbspi-84390	55	10	anova	anova	PROPN
ajbspi-84390	55	11	,	,	PUNCT
ajbspi-84390	55	12	followed	follow	VERB
ajbspi-84390	55	13	by	by	ADP
ajbspi-84390	55	14	tukey	tukey	PROPN
ajbspi-84390	55	15	’s	’s	PART
ajbspi-84390	55	16	post	post	ADJ
ajbspi-84390	55	17	-	-	ADJ
ajbspi-84390	55	18	hoc	hoc	ADJ
ajbspi-84390	55	19	test	test	NOUN
ajbspi-84390	55	20	for	for	ADP
ajbspi-84390	55	21	multiple	multiple	ADJ
ajbspi-84390	55	22	comparisons	comparison	NOUN
ajbspi-84390	55	23	.	.	PUNCT
ajbspi-84390	56	1	p	p	X
ajbspi-84390	56	2	-	-	PUNCT
ajbspi-84390	56	3	values	value	NOUN
ajbspi-84390	56	4	less	less	ADJ
ajbspi-84390	56	5	than	than	ADP
ajbspi-84390	56	6	0.05	0.05	NUM
ajbspi-84390	56	7	were	be	AUX
ajbspi-84390	56	8	considered	consider	VERB
ajbspi-84390	56	9	statistically	statistically	ADV
ajbspi-84390	56	10	significant	significant	ADJ
ajbspi-84390	56	11	.	.	PUNCT
ajbspi-84390	57	1	results	result	VERB
ajbspi-84390	57	2	the	the	DET
ajbspi-84390	57	3	protocol	protocol	NOUN
ajbspi-84390	57	4	successfully	successfully	ADV
ajbspi-84390	57	5	isolated	isolate	VERB
ajbspi-84390	57	6	single	single	ADJ
ajbspi-84390	57	7	-	-	PUNCT
ajbspi-84390	57	8	eye	eye	NOUN
ajbspi-84390	57	9	porcine	porcine	NOUN
ajbspi-84390	57	10	rpe	rpe	PROPN
ajbspi-84390	57	11	cells	cell	NOUN
ajbspi-84390	57	12	with	with	ADP
ajbspi-84390	57	13	high	high	ADJ
ajbspi-84390	57	14	yield	yield	NOUN
ajbspi-84390	57	15	and	and	CCONJ
ajbspi-84390	57	16	viability	viability	NOUN
ajbspi-84390	57	17	.	.	PUNCT
ajbspi-84390	58	1	upon	upon	SCONJ
ajbspi-84390	58	2	plating	plating	NOUN
ajbspi-84390	58	3	,	,	PUNCT
ajbspi-84390	58	4	the	the	DET
ajbspi-84390	58	5	rpe	rpe	PROPN
ajbspi-84390	58	6	cells	cell	NOUN
ajbspi-84390	58	7	adhered	adhere	VERB
ajbspi-84390	58	8	to	to	ADP
ajbspi-84390	58	9	the	the	DET
ajbspi-84390	58	10	culture	culture	NOUN
ajbspi-84390	58	11	surface	surface	NOUN
ajbspi-84390	58	12	and	and	CCONJ
ajbspi-84390	58	13	exhibited	exhibit	VERB
ajbspi-84390	58	14	characteristic	characteristic	ADJ
ajbspi-84390	58	15	polygonal	polygonal	ADJ
ajbspi-84390	58	16	morphology	morphology	NOUN
ajbspi-84390	58	17	within	within	ADP
ajbspi-84390	58	18	24	24	NUM
ajbspi-84390	58	19	hours	hour	NOUN
ajbspi-84390	58	20	.	.	PUNCT
ajbspi-84390	59	1	cells	cell	NOUN
ajbspi-84390	59	2	proliferated	proliferate	VERB
ajbspi-84390	59	3	rapidly	rapidly	ADV
ajbspi-84390	59	4	,	,	PUNCT
ajbspi-84390	59	5	forming	form	VERB
ajbspi-84390	59	6	a	a	DET
ajbspi-84390	59	7	monolayer	monolayer	NOUN
ajbspi-84390	59	8	by	by	ADP
ajbspi-84390	59	9	day	day	NOUN
ajbspi-84390	59	10	4	4	NUM
ajbspi-84390	59	11	-	-	SYM
ajbspi-84390	59	12	5	5	NUM
ajbspi-84390	59	13	of	of	ADP
ajbspi-84390	59	14	culture	culture	NOUN
ajbspi-84390	59	15	,	,	PUNCT
ajbspi-84390	59	16	and	and	CCONJ
ajbspi-84390	59	17	reached	reach	VERB
ajbspi-84390	59	18	full	full	ADJ
ajbspi-84390	59	19	confluence	confluence	NOUN
ajbspi-84390	59	20	by	by	ADP
ajbspi-84390	59	21	day	day	NOUN
ajbspi-84390	59	22	7	7	NUM
ajbspi-84390	59	23	.	.	PUNCT
ajbspi-84390	60	1	the	the	DET
ajbspi-84390	60	2	cells	cell	NOUN
ajbspi-84390	60	3	displayed	display	VERB
ajbspi-84390	60	4	typical	typical	ADJ
ajbspi-84390	60	5	rpe	rpe	PROPN
ajbspi-84390	60	6	features	feature	NOUN
ajbspi-84390	60	7	,	,	PUNCT
ajbspi-84390	60	8	including	include	VERB
ajbspi-84390	60	9	pigmentation	pigmentation	NOUN
ajbspi-84390	60	10	and	and	CCONJ
ajbspi-84390	60	11	the	the	DET
ajbspi-84390	60	12	formation	formation	NOUN
ajbspi-84390	60	13	of	of	ADP
ajbspi-84390	60	14	tight	tight	ADJ
ajbspi-84390	60	15	junctions	junction	NOUN
ajbspi-84390	60	16	.	.	PUNCT
ajbspi-84390	61	1	immunocytochemical	immunocytochemical	ADJ
ajbspi-84390	61	2	analysis	analysis	NOUN
ajbspi-84390	61	3	revealed	reveal	VERB
ajbspi-84390	61	4	the	the	DET
ajbspi-84390	61	5	expression	expression	NOUN
ajbspi-84390	61	6	of	of	ADP
ajbspi-84390	61	7	rpe	rpe	PROPN
ajbspi-84390	61	8	-	-	PUNCT
ajbspi-84390	61	9	specific	specific	ADJ
ajbspi-84390	61	10	markers	marker	NOUN
ajbspi-84390	61	11	such	such	ADJ
ajbspi-84390	61	12	as	as	ADP
ajbspi-84390	61	13	bestrophin	bestrophin	NOUN
ajbspi-84390	61	14	and	and	CCONJ
ajbspi-84390	61	15	pax6	pax6	PROPN
ajbspi-84390	61	16	,	,	PUNCT
ajbspi-84390	61	17	confirming	confirm	VERB
ajbspi-84390	61	18	the	the	DET
ajbspi-84390	61	19	identity	identity	NOUN
ajbspi-84390	61	20	of	of	ADP
ajbspi-84390	61	21	the	the	DET
ajbspi-84390	61	22	cultured	cultured	ADJ
ajbspi-84390	61	23	cells	cell	NOUN
ajbspi-84390	61	24	as	as	ADP
ajbspi-84390	61	25	rpe	rpe	PROPN
ajbspi-84390	61	26	.	.	PUNCT
ajbspi-84390	62	1	additionally	additionally	ADV
ajbspi-84390	62	2	,	,	PUNCT
ajbspi-84390	62	3	the	the	DET
ajbspi-84390	62	4	cells	cell	NOUN
ajbspi-84390	62	5	stained	stain	VERB
ajbspi-84390	62	6	positively	positively	ADV
ajbspi-84390	62	7	for	for	ADP
ajbspi-84390	62	8	zo-1	zo-1	NUM
ajbspi-84390	62	9	,	,	PUNCT
ajbspi-84390	62	10	indicating	indicate	VERB
ajbspi-84390	62	11	the	the	DET
ajbspi-84390	62	12	formation	formation	NOUN
ajbspi-84390	62	13	of	of	ADP
ajbspi-84390	62	14	tight	tight	ADJ
ajbspi-84390	62	15	junctions	junction	NOUN
ajbspi-84390	62	16	,	,	PUNCT
ajbspi-84390	62	17	a	a	DET
ajbspi-84390	62	18	hallmark	hallmark	NOUN
ajbspi-84390	62	19	of	of	ADP
ajbspi-84390	62	20	rpe	rpe	PROPN
ajbspi-84390	62	21	cell	cell	NOUN
ajbspi-84390	62	22	differentiation	differentiation	NOUN
ajbspi-84390	62	23	.	.	PUNCT
ajbspi-84390	63	1	the	the	DET
ajbspi-84390	63	2	functional	functional	ADJ
ajbspi-84390	63	3	assays	assay	NOUN
ajbspi-84390	63	4	demonstrated	demonstrate	VERB
ajbspi-84390	63	5	that	that	SCONJ
ajbspi-84390	63	6	the	the	DET
ajbspi-84390	63	7	cultured	cultured	ADJ
ajbspi-84390	63	8	rpe	rpe	PROPN
ajbspi-84390	63	9	cells	cell	NOUN
ajbspi-84390	63	10	retained	retain	VERB
ajbspi-84390	63	11	their	their	PRON
ajbspi-84390	63	12	ability	ability	NOUN
ajbspi-84390	63	13	to	to	PART
ajbspi-84390	63	14	perform	perform	VERB
ajbspi-84390	63	15	phagocytosis	phagocytosis	NOUN
ajbspi-84390	63	16	of	of	ADP
ajbspi-84390	63	17	photoreceptor	photoreceptor	NOUN
ajbspi-84390	63	18	outer	outer	ADJ
ajbspi-84390	63	19	segment	segment	NOUN
ajbspi-84390	63	20	-	-	PUNCT
ajbspi-84390	63	21	like	like	ADJ
ajbspi-84390	63	22	particles	particle	NOUN
ajbspi-84390	63	23	,	,	PUNCT
ajbspi-84390	63	24	confirming	confirm	VERB
ajbspi-84390	63	25	their	their	PRON
ajbspi-84390	63	26	functional	functional	ADJ
ajbspi-84390	63	27	activity	activity	NOUN
ajbspi-84390	63	28	.	.	PUNCT
ajbspi-84390	64	1	transepithelial	transepithelial	ADJ
ajbspi-84390	64	2	resistance	resistance	NOUN
ajbspi-84390	64	3	(	(	PUNCT
ajbspi-84390	64	4	ter	ter	NOUN
ajbspi-84390	64	5	)	)	PUNCT
ajbspi-84390	64	6	measurements	measurement	NOUN
ajbspi-84390	64	7	showed	show	VERB
ajbspi-84390	64	8	a	a	DET
ajbspi-84390	64	9	significant	significant	ADJ
ajbspi-84390	64	10	increase	increase	NOUN
ajbspi-84390	64	11	in	in	ADP
ajbspi-84390	64	12	resistance	resistance	NOUN
ajbspi-84390	64	13	over	over	ADP
ajbspi-84390	64	14	time	time	NOUN
ajbspi-84390	64	15	,	,	PUNCT
ajbspi-84390	64	16	indicating	indicate	VERB
ajbspi-84390	64	17	that	that	SCONJ
ajbspi-84390	64	18	the	the	DET
ajbspi-84390	64	19	cells	cell	NOUN
ajbspi-84390	64	20	were	be	AUX
ajbspi-84390	64	21	forming	form	VERB
ajbspi-84390	64	22	an	an	DET
ajbspi-84390	64	23	intact	intact	ADJ
ajbspi-84390	64	24	monolayer	monolayer	NOUN
ajbspi-84390	64	25	with	with	ADP
ajbspi-84390	64	26	functional	functional	ADJ
ajbspi-84390	64	27	barrier	barrier	NOUN
ajbspi-84390	64	28	properties	property	NOUN
ajbspi-84390	64	29	.	.	PUNCT
ajbspi-84390	65	1	discussion	discussion	NOUN
ajbspi-84390	65	2	this	this	DET
ajbspi-84390	65	3	study	study	NOUN
ajbspi-84390	65	4	presents	present	VERB
ajbspi-84390	65	5	a	a	DET
ajbspi-84390	65	6	validated	validated	ADJ
ajbspi-84390	65	7	and	and	CCONJ
ajbspi-84390	65	8	reproducible	reproducible	ADJ
ajbspi-84390	65	9	protocol	protocol	NOUN
ajbspi-84390	65	10	for	for	ADP
ajbspi-84390	65	11	the	the	DET
ajbspi-84390	65	12	isolation	isolation	NOUN
ajbspi-84390	65	13	and	and	CCONJ
ajbspi-84390	65	14	culture	culture	NOUN
ajbspi-84390	65	15	of	of	ADP
ajbspi-84390	65	16	single	single	ADJ
ajbspi-84390	65	17	-	-	PUNCT
ajbspi-84390	65	18	eye	eye	NOUN
ajbspi-84390	65	19	porcine	porcine	NOUN
ajbspi-84390	65	20	rpe	rpe	PROPN
ajbspi-84390	65	21	cells	cell	NOUN
ajbspi-84390	65	22	.	.	PUNCT
ajbspi-84390	66	1	the	the	DET
ajbspi-84390	66	2	approach	approach	NOUN
ajbspi-84390	66	3	described	describe	VERB
ajbspi-84390	66	4	in	in	ADP
ajbspi-84390	66	5	this	this	DET
ajbspi-84390	66	6	article	article	NOUN
ajbspi-84390	66	7	ensures	ensure	VERB
ajbspi-84390	66	8	high	high	ADJ
ajbspi-84390	66	9	cell	cell	NOUN
ajbspi-84390	66	10	yield	yield	NOUN
ajbspi-84390	66	11	,	,	PUNCT
ajbspi-84390	66	12	robust	robust	ADJ
ajbspi-84390	66	13	proliferation	proliferation	NOUN
ajbspi-84390	66	14	,	,	PUNCT
ajbspi-84390	66	15	and	and	CCONJ
ajbspi-84390	66	16	successful	successful	ADJ
ajbspi-84390	66	17	differentiation	differentiation	NOUN
ajbspi-84390	66	18	into	into	ADP
ajbspi-84390	66	19	functional	functional	ADJ
ajbspi-84390	66	20	rpe	rpe	PROPN
ajbspi-84390	66	21	cells	cell	NOUN
ajbspi-84390	66	22	,	,	PUNCT
ajbspi-84390	66	23	making	make	VERB
ajbspi-84390	66	24	it	it	PRON
ajbspi-84390	66	25	an	an	DET
ajbspi-84390	66	26	ideal	ideal	ADJ
ajbspi-84390	66	27	model	model	NOUN
ajbspi-84390	66	28	for	for	ADP
ajbspi-84390	66	29	retinal	retinal	ADJ
ajbspi-84390	66	30	research	research	NOUN
ajbspi-84390	66	31	.	.	PUNCT
ajbspi-84390	67	1	the	the	DET
ajbspi-84390	67	2	results	result	NOUN
ajbspi-84390	67	3	of	of	ADP
ajbspi-84390	67	4	immunocytochemistry	immunocytochemistry	NOUN
ajbspi-84390	67	5	and	and	CCONJ
ajbspi-84390	67	6	functional	functional	ADJ
ajbspi-84390	67	7	assays	assay	NOUN
ajbspi-84390	67	8	confirmed	confirm	VERB
ajbspi-84390	67	9	that	that	SCONJ
ajbspi-84390	67	10	the	the	DET
ajbspi-84390	67	11	cultured	cultured	ADJ
ajbspi-84390	67	12	rpe	rpe	PROPN
ajbspi-84390	67	13	cells	cell	NOUN
ajbspi-84390	67	14	maintained	maintain	VERB
ajbspi-84390	67	15	key	key	ADJ
ajbspi-84390	67	16	physiological	physiological	ADJ
ajbspi-84390	67	17	characteristics	characteristic	NOUN
ajbspi-84390	67	18	,	,	PUNCT
ajbspi-84390	67	19	such	such	ADJ
ajbspi-84390	67	20	as	as	ADP
ajbspi-84390	67	21	the	the	DET
ajbspi-84390	67	22	expression	expression	NOUN
ajbspi-84390	67	23	of	of	ADP
ajbspi-84390	67	24	rpe	rpe	PROPN
ajbspi-84390	67	25	-	-	PUNCT
ajbspi-84390	67	26	specific	specific	ADJ
ajbspi-84390	67	27	markers	marker	NOUN
ajbspi-84390	67	28	and	and	CCONJ
ajbspi-84390	67	29	the	the	DET
ajbspi-84390	67	30	ability	ability	NOUN
ajbspi-84390	67	31	to	to	PART
ajbspi-84390	67	32	perform	perform	VERB
ajbspi-84390	67	33	phagocytosis	phagocytosis	NOUN
ajbspi-84390	67	34	.	.	PUNCT
ajbspi-84390	68	1	furthermore	furthermore	ADV
ajbspi-84390	68	2	,	,	PUNCT
ajbspi-84390	68	3	the	the	DET
ajbspi-84390	68	4	increase	increase	NOUN
ajbspi-84390	68	5	in	in	ADP
ajbspi-84390	68	6	transepithelial	transepithelial	ADJ
ajbspi-84390	68	7	resistance	resistance	NOUN
ajbspi-84390	68	8	over	over	ADP
ajbspi-84390	68	9	time	time	NOUN
ajbspi-84390	68	10	suggests	suggest	VERB
ajbspi-84390	68	11	that	that	SCONJ
ajbspi-84390	68	12	the	the	DET
ajbspi-84390	68	13	cells	cell	NOUN
ajbspi-84390	68	14	established	establish	VERB
ajbspi-84390	68	15	a	a	DET
ajbspi-84390	68	16	functional	functional	ADJ
ajbspi-84390	68	17	monolayer	monolayer	NOUN
ajbspi-84390	68	18	,	,	PUNCT
ajbspi-84390	68	19	which	which	PRON
ajbspi-84390	68	20	is	be	AUX
ajbspi-84390	68	21	critical	critical	ADJ
ajbspi-84390	68	22	for	for	ADP
ajbspi-84390	68	23	studying	study	VERB
ajbspi-84390	68	24	the	the	DET
ajbspi-84390	68	25	blood	blood	NOUN
ajbspi-84390	68	26	-	-	PUNCT
ajbspi-84390	68	27	retinal	retinal	ADJ
ajbspi-84390	68	28	barrier	barrier	NOUN
ajbspi-84390	68	29	and	and	CCONJ
ajbspi-84390	68	30	other	other	ADJ
ajbspi-84390	68	31	rpe	rpe	PROPN
ajbspi-84390	68	32	functions	function	NOUN
ajbspi-84390	68	33	.	.	PUNCT
ajbspi-84390	69	1	this	this	DET
ajbspi-84390	69	2	protocol	protocol	NOUN
ajbspi-84390	69	3	has	have	VERB
ajbspi-84390	69	4	several	several	ADJ
ajbspi-84390	69	5	advantages	advantage	NOUN
ajbspi-84390	69	6	over	over	ADP
ajbspi-84390	69	7	existing	exist	VERB
ajbspi-84390	69	8	methods	method	NOUN
ajbspi-84390	69	9	,	,	PUNCT
ajbspi-84390	69	10	including	include	VERB
ajbspi-84390	69	11	its	its	PRON
ajbspi-84390	69	12	reproducibility	reproducibility	NOUN
ajbspi-84390	69	13	,	,	PUNCT
ajbspi-84390	69	14	simplicity	simplicity	NOUN
ajbspi-84390	69	15	,	,	PUNCT
ajbspi-84390	69	16	and	and	CCONJ
ajbspi-84390	69	17	ability	ability	NOUN
ajbspi-84390	69	18	to	to	PART
ajbspi-84390	69	19	generate	generate	VERB
ajbspi-84390	69	20	large	large	ADJ
ajbspi-84390	69	21	numbers	number	NOUN
ajbspi-84390	69	22	of	of	ADP
ajbspi-84390	69	23	cells	cell	NOUN
ajbspi-84390	69	24	for	for	ADP
ajbspi-84390	69	25	experimentation	experimentation	NOUN
ajbspi-84390	69	26	.	.	PUNCT
ajbspi-84390	70	1	by	by	ADP
ajbspi-84390	70	2	providing	provide	VERB
ajbspi-84390	70	3	a	a	DET
ajbspi-84390	70	4	reliable	reliable	ADJ
ajbspi-84390	70	5	method	method	NOUN
ajbspi-84390	70	6	for	for	ADP
ajbspi-84390	70	7	culturing	culture	VERB
ajbspi-84390	70	8	porcine	porcine	NOUN
ajbspi-84390	70	9	rpe	rpe	PROPN
ajbspi-84390	70	10	cells	cell	NOUN
ajbspi-84390	70	11	,	,	PUNCT
ajbspi-84390	70	12	this	this	DET
ajbspi-84390	70	13	study	study	NOUN
ajbspi-84390	70	14	paves	pave	VERB
ajbspi-84390	70	15	the	the	DET
ajbspi-84390	70	16	way	way	NOUN
ajbspi-84390	70	17	for	for	ADP
ajbspi-84390	70	18	future	future	ADJ
ajbspi-84390	70	19	research	research	NOUN
ajbspi-84390	70	20	into	into	ADP
ajbspi-84390	70	21	retinal	retinal	ADJ
ajbspi-84390	70	22	diseases	disease	NOUN
ajbspi-84390	70	23	,	,	PUNCT
ajbspi-84390	70	24	drug	drug	NOUN
ajbspi-84390	70	25	screening	screening	NOUN
ajbspi-84390	70	26	,	,	PUNCT
ajbspi-84390	70	27	and	and	CCONJ
ajbspi-84390	70	28	regenerative	regenerative	ADJ
ajbspi-84390	70	29	therapies	therapy	NOUN
ajbspi-84390	70	30	for	for	ADP
ajbspi-84390	70	31	retinal	retinal	ADJ
ajbspi-84390	70	32	degenerative	degenerative	ADJ
ajbspi-84390	70	33	conditions	condition	NOUN
ajbspi-84390	70	34	.	.	PUNCT
ajbspi-84390	71	1	however	however	ADV
ajbspi-84390	71	2	,	,	PUNCT
ajbspi-84390	71	3	it	it	PRON
ajbspi-84390	71	4	is	be	AUX
ajbspi-84390	71	5	important	important	ADJ
ajbspi-84390	71	6	to	to	PART
ajbspi-84390	71	7	note	note	VERB
ajbspi-84390	71	8	that	that	SCONJ
ajbspi-84390	71	9	this	this	DET
ajbspi-84390	71	10	protocol	protocol	NOUN
ajbspi-84390	71	11	was	be	AUX
ajbspi-84390	71	12	performed	perform	VERB
ajbspi-84390	71	13	using	use	VERB
ajbspi-84390	71	14	porcine	porcine	NOUN
ajbspi-84390	71	15	eyes	eye	NOUN
ajbspi-84390	71	16	obtained	obtain	VERB
ajbspi-84390	71	17	from	from	ADP
ajbspi-84390	71	18	a	a	DET
ajbspi-84390	71	19	single	single	ADJ
ajbspi-84390	71	20	source	source	NOUN
ajbspi-84390	71	21	.	.	PUNCT
ajbspi-84390	72	1	variations	variation	NOUN
ajbspi-84390	72	2	in	in	ADP
ajbspi-84390	72	3	tissue	tissue	NOUN
ajbspi-84390	72	4	quality	quality	NOUN
ajbspi-84390	72	5	and	and	CCONJ
ajbspi-84390	72	6	donor	donor	NOUN
ajbspi-84390	72	7	age	age	NOUN
ajbspi-84390	72	8	could	could	AUX
ajbspi-84390	72	9	influence	influence	VERB
ajbspi-84390	72	10	the	the	DET
ajbspi-84390	72	11	outcome	outcome	NOUN
ajbspi-84390	72	12	of	of	ADP
ajbspi-84390	72	13	the	the	DET
ajbspi-84390	72	14	cultures	culture	NOUN
ajbspi-84390	72	15	.	.	PUNCT
ajbspi-84390	73	1	future	future	ADJ
ajbspi-84390	73	2	studies	study	NOUN
ajbspi-84390	73	3	should	should	AUX
ajbspi-84390	73	4	evaluate	evaluate	VERB
ajbspi-84390	73	5	the	the	DET
ajbspi-84390	73	6	reproducibility	reproducibility	NOUN
ajbspi-84390	73	7	of	of	ADP
ajbspi-84390	73	8	the	the	DET
ajbspi-84390	73	9	protocol	protocol	NOUN
ajbspi-84390	73	10	across	across	ADP
ajbspi-84390	73	11	different	different	ADJ
ajbspi-84390	73	12	sources	source	NOUN
ajbspi-84390	73	13	of	of	ADP
ajbspi-84390	73	14	porcine	porcine	NOUN
ajbspi-84390	73	15	tissue	tissue	NOUN
ajbspi-84390	73	16	and	and	CCONJ
ajbspi-84390	73	17	investigate	investigate	VERB
ajbspi-84390	73	18	potential	potential	ADJ
ajbspi-84390	73	19	variations	variation	NOUN
ajbspi-84390	73	20	in	in	ADP
ajbspi-84390	73	21	rpe	rpe	PROPN
ajbspi-84390	73	22	cell	cell	NOUN
ajbspi-84390	73	23	behavior	behavior	NOUN
ajbspi-84390	73	24	under	under	ADP
ajbspi-84390	73	25	different	different	ADJ
ajbspi-84390	73	26	experimental	experimental	ADJ
ajbspi-84390	73	27	conditions	condition	NOUN
ajbspi-84390	73	28	.	.	PUNCT
ajbspi-84390	74	1	additionally	additionally	ADV
ajbspi-84390	74	2	,	,	PUNCT
ajbspi-84390	74	3	the	the	DET
ajbspi-84390	74	4	long	long	ADJ
ajbspi-84390	74	5	-	-	PUNCT
ajbspi-84390	74	6	term	term	NOUN
ajbspi-84390	74	7	viability	viability	NOUN
ajbspi-84390	74	8	and	and	CCONJ
ajbspi-84390	74	9	functionality	functionality	NOUN
ajbspi-84390	74	10	of	of	ADP
ajbspi-84390	74	11	cultured	cultured	ADJ
ajbspi-84390	74	12	rpe	rpe	PROPN
ajbspi-84390	74	13	cells	cell	NOUN
ajbspi-84390	74	14	,	,	PUNCT
ajbspi-84390	74	15	particularly	particularly	ADV
ajbspi-84390	74	16	for	for	ADP
ajbspi-84390	74	17	use	use	NOUN
ajbspi-84390	74	18	in	in	ADP
ajbspi-84390	74	19	transplantation	transplantation	NOUN
ajbspi-84390	74	20	or	or	CCONJ
ajbspi-84390	74	21	retinal	retinal	ADJ
ajbspi-84390	74	22	regenerative	regenerative	ADJ
ajbspi-84390	74	23	applications	application	NOUN
ajbspi-84390	74	24	,	,	PUNCT
ajbspi-84390	74	25	should	should	AUX
ajbspi-84390	74	26	be	be	AUX
ajbspi-84390	74	27	further	far	ADV
ajbspi-84390	74	28	explored	explore	VERB
ajbspi-84390	74	29	.	.	PUNCT
ajbspi-84390	75	1	the	the	DET
ajbspi-84390	75	2	present	present	ADJ
ajbspi-84390	75	3	study	study	NOUN
ajbspi-84390	75	4	highlights	highlight	VERB
ajbspi-84390	75	5	the	the	DET
ajbspi-84390	75	6	development	development	NOUN
ajbspi-84390	75	7	and	and	CCONJ
ajbspi-84390	75	8	validation	validation	NOUN
ajbspi-84390	75	9	of	of	ADP
ajbspi-84390	75	10	a	a	DET
ajbspi-84390	75	11	reproducible	reproducible	ADJ
ajbspi-84390	75	12	protocol	protocol	NOUN
ajbspi-84390	75	13	for	for	ADP
ajbspi-84390	75	14	culturing	culture	VERB
ajbspi-84390	75	15	single	single	ADJ
ajbspi-84390	75	16	-	-	PUNCT
ajbspi-84390	75	17	eye	eye	NOUN
ajbspi-84390	75	18	porcine	porcine	NOUN
ajbspi-84390	75	19	retinal	retinal	ADJ
ajbspi-84390	75	20	pigment	pigment	NOUN
ajbspi-84390	75	21	epithelium	epithelium	NOUN
ajbspi-84390	75	22	(	(	PUNCT
ajbspi-84390	75	23	rpe	rpe	PROPN
ajbspi-84390	75	24	)	)	PUNCT
ajbspi-84390	75	25	cells	cell	NOUN
ajbspi-84390	75	26	,	,	PUNCT
ajbspi-84390	75	27	providing	provide	VERB
ajbspi-84390	75	28	a	a	DET
ajbspi-84390	75	29	reliable	reliable	ADJ
ajbspi-84390	75	30	model	model	NOUN
ajbspi-84390	75	31	for	for	ADP
ajbspi-84390	75	32	retinal	retinal	ADJ
ajbspi-84390	75	33	research	research	NOUN
ajbspi-84390	75	34	.	.	PUNCT
ajbspi-84390	76	1	the	the	DET
ajbspi-84390	76	2	successful	successful	ADJ
ajbspi-84390	76	3	isolation	isolation	NOUN
ajbspi-84390	76	4	and	and	CCONJ
ajbspi-84390	76	5	cultivation	cultivation	NOUN
ajbspi-84390	76	6	of	of	ADP
ajbspi-84390	76	7	porcine	porcine	NOUN
ajbspi-84390	76	8	rpe	rpe	PROPN
ajbspi-84390	76	9	cells	cell	NOUN
ajbspi-84390	76	10	is	be	AUX
ajbspi-84390	76	11	an	an	DET
ajbspi-84390	76	12	essential	essential	ADJ
ajbspi-84390	76	13	first	first	ADJ
ajbspi-84390	76	14	step	step	NOUN
ajbspi-84390	76	15	toward	toward	ADP
ajbspi-84390	76	16	studying	study	VERB
ajbspi-84390	76	17	retinal	retinal	ADJ
ajbspi-84390	76	18	diseases	disease	NOUN
ajbspi-84390	76	19	and	and	CCONJ
ajbspi-84390	76	20	testing	test	VERB
ajbspi-84390	76	21	potential	potential	ADJ
ajbspi-84390	76	22	therapeutic	therapeutic	ADJ
ajbspi-84390	76	23	strategies	strategy	NOUN
ajbspi-84390	76	24	.	.	PUNCT
ajbspi-84390	77	1	this	this	DET
ajbspi-84390	77	2	section	section	NOUN
ajbspi-84390	77	3	will	will	AUX
ajbspi-84390	77	4	discuss	discuss	VERB
ajbspi-84390	77	5	the	the	DET
ajbspi-84390	77	6	key	key	ADJ
ajbspi-84390	77	7	findings	finding	NOUN
ajbspi-84390	77	8	,	,	PUNCT
ajbspi-84390	77	9	potential	potential	ADJ
ajbspi-84390	77	10	challenges	challenge	NOUN
ajbspi-84390	77	11	,	,	PUNCT
ajbspi-84390	77	12	and	and	CCONJ
ajbspi-84390	77	13	opportunities	opportunity	NOUN
ajbspi-84390	77	14	for	for	ADP
ajbspi-84390	77	15	future	future	ADJ
ajbspi-84390	77	16	research	research	NOUN
ajbspi-84390	77	17	using	use	VERB
ajbspi-84390	77	18	this	this	DET
ajbspi-84390	77	19	protocol	protocol	NOUN
ajbspi-84390	77	20	,	,	PUNCT
ajbspi-84390	77	21	including	include	VERB
ajbspi-84390	77	22	its	its	PRON
ajbspi-84390	77	23	application	application	NOUN
ajbspi-84390	77	24	in	in	ADP
ajbspi-84390	77	25	drug	drug	NOUN
ajbspi-84390	77	26	screening	screening	NOUN
ajbspi-84390	77	27	,	,	PUNCT
ajbspi-84390	77	28	disease	disease	NOUN
ajbspi-84390	77	29	modeling	modeling	NOUN
ajbspi-84390	77	30	,	,	PUNCT
ajbspi-84390	77	31	and	and	CCONJ
ajbspi-84390	77	32	regenerative	regenerative	ADJ
ajbspi-84390	77	33	therapies	therapy	NOUN
ajbspi-84390	77	34	.	.	PUNCT
ajbspi-84390	78	1	1	1	X
ajbspi-84390	78	2	.	.	X
ajbspi-84390	78	3	cell	cell	NOUN
ajbspi-84390	78	4	isolation	isolation	NOUN
ajbspi-84390	78	5	and	and	CCONJ
ajbspi-84390	78	6	culture	culture	NOUN
ajbspi-84390	78	7	protocol	protocol	NOUN
ajbspi-84390	78	8	one	one	NUM
ajbspi-84390	78	9	of	of	ADP
ajbspi-84390	78	10	the	the	DET
ajbspi-84390	78	11	primary	primary	ADJ
ajbspi-84390	78	12	goals	goal	NOUN
ajbspi-84390	78	13	of	of	ADP
ajbspi-84390	78	14	this	this	DET
ajbspi-84390	78	15	study	study	NOUN
ajbspi-84390	78	16	was	be	AUX
ajbspi-84390	78	17	to	to	PART
ajbspi-84390	78	18	establish	establish	VERB
ajbspi-84390	78	19	a	a	DET
ajbspi-84390	78	20	reproducible	reproducible	ADJ
ajbspi-84390	78	21	method	method	NOUN
ajbspi-84390	78	22	for	for	ADP
ajbspi-84390	78	23	isolating	isolate	VERB
ajbspi-84390	78	24	porcine	porcine	NOUN
ajbspi-84390	78	25	rpe	rpe	PROPN
ajbspi-84390	78	26	cells	cell	NOUN
ajbspi-84390	78	27	from	from	ADP
ajbspi-84390	78	28	retinal	retinal	ADJ
ajbspi-84390	78	29	tissue	tissue	NOUN
ajbspi-84390	78	30	.	.	PUNCT
ajbspi-84390	79	1	this	this	DET
ajbspi-84390	79	2	protocol	protocol	NOUN
ajbspi-84390	79	3	utilizes	utilize	VERB
ajbspi-84390	79	4	a	a	DET
ajbspi-84390	79	5	combination	combination	NOUN
ajbspi-84390	79	6	of	of	ADP
ajbspi-84390	79	7	mechanical	mechanical	ADJ
ajbspi-84390	79	8	dissection	dissection	NOUN
ajbspi-84390	79	9	and	and	CCONJ
ajbspi-84390	79	10	enzymatic	enzymatic	ADJ
ajbspi-84390	79	11	digestion	digestion	NOUN
ajbspi-84390	79	12	to	to	PART
ajbspi-84390	79	13	isolate	isolate	VERB
ajbspi-84390	79	14	the	the	DET
ajbspi-84390	79	15	rpe	rpe	PROPN
ajbspi-84390	79	16	monolayer	monolayer	NOUN
ajbspi-84390	79	17	from	from	ADP
ajbspi-84390	79	18	the	the	DET
ajbspi-84390	79	19	underlying	underlie	VERB
ajbspi-84390	79	20	choroid	choroid	NOUN
ajbspi-84390	79	21	.	.	PUNCT
ajbspi-84390	80	1	the	the	DET
ajbspi-84390	80	2	tissue	tissue	NOUN
ajbspi-84390	80	3	was	be	AUX
ajbspi-84390	80	4	carefully	carefully	ADV
ajbspi-84390	80	5	dissected	dissect	VERB
ajbspi-84390	80	6	,	,	PUNCT
ajbspi-84390	80	7	ensuring	ensure	VERB
ajbspi-84390	80	8	minimal	minimal	ADJ
ajbspi-84390	80	9	contamination	contamination	NOUN
ajbspi-84390	80	10	from	from	ADP
ajbspi-84390	80	11	surrounding	surround	VERB
ajbspi-84390	80	12	structures	structure	NOUN
ajbspi-84390	80	13	,	,	PUNCT
ajbspi-84390	80	14	and	and	CCONJ
ajbspi-84390	80	15	dissociated	dissociate	VERB
ajbspi-84390	80	16	using	use	VERB
ajbspi-84390	80	17	trypsin	trypsin	NOUN
ajbspi-84390	80	18	,	,	PUNCT
ajbspi-84390	80	19	which	which	PRON
ajbspi-84390	80	20	allowed	allow	VERB
ajbspi-84390	80	21	for	for	ADP
ajbspi-84390	80	22	the	the	DET
ajbspi-84390	80	23	effective	effective	ADJ
ajbspi-84390	80	24	separation	separation	NOUN
ajbspi-84390	80	25	of	of	ADP
ajbspi-84390	80	26	individual	individual	ADJ
ajbspi-84390	80	27	cells	cell	NOUN
ajbspi-84390	80	28	while	while	SCONJ
ajbspi-84390	80	29	maintaining	maintain	VERB
ajbspi-84390	80	30	high	high	ADJ
ajbspi-84390	80	31	cell	cell	NOUN
ajbspi-84390	80	32	viability	viability	NOUN
ajbspi-84390	80	33	.	.	PUNCT
ajbspi-84390	81	1	the	the	DET
ajbspi-84390	81	2	results	result	NOUN
ajbspi-84390	81	3	showed	show	VERB
ajbspi-84390	81	4	that	that	SCONJ
ajbspi-84390	81	5	the	the	DET
ajbspi-84390	81	6	protocol	protocol	NOUN
ajbspi-84390	81	7	successfully	successfully	ADV
ajbspi-84390	81	8	yielded	yield	VERB
ajbspi-84390	81	9	a	a	DET
ajbspi-84390	81	10	consistent	consistent	ADJ
ajbspi-84390	81	11	number	number	NOUN
ajbspi-84390	81	12	of	of	ADP
ajbspi-84390	81	13	viable	viable	ADJ
ajbspi-84390	81	14	cells	cell	NOUN
ajbspi-84390	81	15	,	,	PUNCT
ajbspi-84390	81	16	with	with	ADP
ajbspi-84390	81	17	high	high	ADJ
ajbspi-84390	81	18	purity	purity	NOUN
ajbspi-84390	81	19	and	and	CCONJ
ajbspi-84390	81	20	minimal	minimal	ADJ
ajbspi-84390	81	21	contamination	contamination	NOUN
ajbspi-84390	81	22	from	from	ADP
ajbspi-84390	81	23	other	other	ADJ
ajbspi-84390	81	24	retinal	retinal	ADJ
ajbspi-84390	81	25	cell	cell	NOUN
ajbspi-84390	81	26	types	type	NOUN
ajbspi-84390	81	27	.	.	PUNCT
ajbspi-84390	82	1	this	this	DET
ajbspi-84390	82	2	high	high	ADJ
ajbspi-84390	82	3	degree	degree	NOUN
ajbspi-84390	82	4	of	of	ADP
ajbspi-84390	82	5	reproducibility	reproducibility	NOUN
ajbspi-84390	82	6	is	be	AUX
ajbspi-84390	82	7	important	important	ADJ
ajbspi-84390	82	8	for	for	ADP
ajbspi-84390	82	9	researchers	researcher	NOUN
ajbspi-84390	82	10	aiming	aim	VERB
ajbspi-84390	82	11	to	to	PART
ajbspi-84390	82	12	obtain	obtain	VERB
ajbspi-84390	82	13	a	a	DET
ajbspi-84390	82	14	reliable	reliable	ADJ
ajbspi-84390	82	15	source	source	NOUN
ajbspi-84390	82	16	of	of	ADP
ajbspi-84390	82	17	rpe	rpe	PROPN
ajbspi-84390	82	18	cells	cell	NOUN
ajbspi-84390	82	19	for	for	ADP
ajbspi-84390	82	20	their	their	PRON
ajbspi-84390	82	21	experiments	experiment	NOUN
ajbspi-84390	82	22	.	.	PUNCT
ajbspi-84390	83	1	additionally	additionally	ADV
ajbspi-84390	83	2	,	,	PUNCT
ajbspi-84390	83	3	the	the	DET
ajbspi-84390	83	4	use	use	NOUN
ajbspi-84390	83	5	of	of	ADP
ajbspi-84390	83	6	a	a	DET
ajbspi-84390	83	7	standard	standard	ADJ
ajbspi-84390	83	8	rpe	rpe	PROPN
ajbspi-84390	83	9	culture	culture	NOUN
ajbspi-84390	83	10	medium	medium	NOUN
ajbspi-84390	83	11	,	,	PUNCT
ajbspi-84390	83	12	which	which	PRON
ajbspi-84390	83	13	includes	include	VERB
ajbspi-84390	83	14	dulbecco	dulbecco	NOUN
ajbspi-84390	83	15	’s	’s	PART
ajbspi-84390	83	16	modified	modify	VERB
ajbspi-84390	83	17	eagle	eagle	PROPN
ajbspi-84390	83	18	medium	medium	NOUN
ajbspi-84390	83	19	(	(	PUNCT
ajbspi-84390	83	20	dmem	dmem	ADJ
ajbspi-84390	83	21	)	)	PUNCT
ajbspi-84390	83	22	american	american	PROPN
ajbspi-84390	83	23	journal	journal	PROPN
ajbspi-84390	83	24	of	of	ADP
ajbspi-84390	83	25	applied	apply	VERB
ajbspi-84390	83	26	science	science	NOUN
ajbspi-84390	83	27	and	and	CCONJ
ajbspi-84390	83	28	technology	technology	NOUN
ajbspi-84390	83	29	4	4	NUM
ajbspi-84390	83	30	https://theusajournals.com/index.php/ajast	https://theusajournals.com/index.php/ajast	VERB
ajbspi-84390	83	31	american	american	PROPN
ajbspi-84390	83	32	journal	journal	PROPN
ajbspi-84390	83	33	of	of	ADP
ajbspi-84390	83	34	applied	apply	VERB
ajbspi-84390	83	35	science	science	NOUN
ajbspi-84390	83	36	and	and	CCONJ
ajbspi-84390	83	37	technology	technology	NOUN
ajbspi-84390	83	38	(	(	PUNCT
ajbspi-84390	83	39	issn	issn	PROPN
ajbspi-84390	83	40	:	:	PUNCT
ajbspi-84390	83	41	2771	2771	NUM
ajbspi-84390	83	42	-	-	SYM
ajbspi-84390	83	43	2745	2745	NUM
ajbspi-84390	83	44	)	)	PUNCT
ajbspi-84390	83	45	supplemented	supplement	VERB
ajbspi-84390	83	46	with	with	ADP
ajbspi-84390	83	47	fetal	fetal	ADJ
ajbspi-84390	83	48	bovine	bovine	NOUN
ajbspi-84390	83	49	serum	serum	NOUN
ajbspi-84390	83	50	(	(	PUNCT
ajbspi-84390	83	51	fbs	fbs	PROPN
ajbspi-84390	83	52	)	)	PUNCT
ajbspi-84390	83	53	and	and	CCONJ
ajbspi-84390	83	54	antibiotics	antibiotic	NOUN
ajbspi-84390	83	55	,	,	PUNCT
ajbspi-84390	83	56	ensures	ensure	VERB
ajbspi-84390	83	57	that	that	SCONJ
ajbspi-84390	83	58	the	the	DET
ajbspi-84390	83	59	isolated	isolated	ADJ
ajbspi-84390	83	60	cells	cell	NOUN
ajbspi-84390	83	61	are	be	AUX
ajbspi-84390	83	62	maintained	maintain	VERB
ajbspi-84390	83	63	in	in	ADP
ajbspi-84390	83	64	an	an	DET
ajbspi-84390	83	65	environment	environment	NOUN
ajbspi-84390	83	66	conducive	conducive	ADJ
ajbspi-84390	83	67	to	to	ADP
ajbspi-84390	83	68	their	their	PRON
ajbspi-84390	83	69	growth	growth	NOUN
ajbspi-84390	83	70	and	and	CCONJ
ajbspi-84390	83	71	differentiation	differentiation	NOUN
ajbspi-84390	83	72	.	.	PUNCT
ajbspi-84390	84	1	however	however	ADV
ajbspi-84390	84	2	,	,	PUNCT
ajbspi-84390	84	3	one	one	NUM
ajbspi-84390	84	4	important	important	ADJ
ajbspi-84390	84	5	aspect	aspect	NOUN
ajbspi-84390	84	6	that	that	PRON
ajbspi-84390	84	7	researchers	researcher	NOUN
ajbspi-84390	84	8	must	must	AUX
ajbspi-84390	84	9	consider	consider	VERB
ajbspi-84390	84	10	when	when	SCONJ
ajbspi-84390	84	11	using	use	VERB
ajbspi-84390	84	12	this	this	DET
ajbspi-84390	84	13	protocol	protocol	NOUN
ajbspi-84390	84	14	is	be	AUX
ajbspi-84390	84	15	the	the	DET
ajbspi-84390	84	16	potential	potential	ADJ
ajbspi-84390	84	17	variability	variability	NOUN
ajbspi-84390	84	18	in	in	ADP
ajbspi-84390	84	19	tissue	tissue	NOUN
ajbspi-84390	84	20	quality	quality	NOUN
ajbspi-84390	84	21	depending	depend	VERB
ajbspi-84390	84	22	on	on	ADP
ajbspi-84390	84	23	the	the	DET
ajbspi-84390	84	24	donor	donor	NOUN
ajbspi-84390	84	25	.	.	PUNCT
ajbspi-84390	85	1	while	while	SCONJ
ajbspi-84390	85	2	the	the	DET
ajbspi-84390	85	3	tissue	tissue	NOUN
ajbspi-84390	85	4	used	use	VERB
ajbspi-84390	85	5	in	in	ADP
ajbspi-84390	85	6	this	this	DET
ajbspi-84390	85	7	study	study	NOUN
ajbspi-84390	85	8	was	be	AUX
ajbspi-84390	85	9	sourced	source	VERB
ajbspi-84390	85	10	from	from	ADP
ajbspi-84390	85	11	a	a	DET
ajbspi-84390	85	12	single	single	ADJ
ajbspi-84390	85	13	abattoir	abattoir	NOUN
ajbspi-84390	85	14	,	,	PUNCT
ajbspi-84390	85	15	different	different	ADJ
ajbspi-84390	85	16	sources	source	NOUN
ajbspi-84390	85	17	of	of	ADP
ajbspi-84390	85	18	porcine	porcine	NOUN
ajbspi-84390	85	19	eyes	eye	NOUN
ajbspi-84390	85	20	or	or	CCONJ
ajbspi-84390	85	21	variations	variation	NOUN
ajbspi-84390	85	22	in	in	ADP
ajbspi-84390	85	23	tissue	tissue	NOUN
ajbspi-84390	85	24	age	age	NOUN
ajbspi-84390	85	25	could	could	AUX
ajbspi-84390	85	26	lead	lead	VERB
ajbspi-84390	85	27	to	to	ADP
ajbspi-84390	85	28	slight	slight	ADJ
ajbspi-84390	85	29	differences	difference	NOUN
ajbspi-84390	85	30	in	in	ADP
ajbspi-84390	85	31	cell	cell	NOUN
ajbspi-84390	85	32	yield	yield	NOUN
ajbspi-84390	85	33	or	or	CCONJ
ajbspi-84390	85	34	viability	viability	NOUN
ajbspi-84390	85	35	.	.	PUNCT
ajbspi-84390	86	1	for	for	ADP
ajbspi-84390	86	2	instance	instance	NOUN
ajbspi-84390	86	3	,	,	PUNCT
ajbspi-84390	86	4	younger	young	ADJ
ajbspi-84390	86	5	animals	animal	NOUN
ajbspi-84390	86	6	might	might	AUX
ajbspi-84390	86	7	provide	provide	VERB
ajbspi-84390	86	8	cells	cell	NOUN
ajbspi-84390	86	9	with	with	ADP
ajbspi-84390	86	10	better	well	ADJ
ajbspi-84390	86	11	proliferative	proliferative	ADJ
ajbspi-84390	86	12	potential	potential	NOUN
ajbspi-84390	86	13	,	,	PUNCT
ajbspi-84390	86	14	while	while	SCONJ
ajbspi-84390	86	15	older	old	ADJ
ajbspi-84390	86	16	animals	animal	NOUN
ajbspi-84390	86	17	may	may	AUX
ajbspi-84390	86	18	have	have	VERB
ajbspi-84390	86	19	cells	cell	NOUN
ajbspi-84390	86	20	that	that	PRON
ajbspi-84390	86	21	are	be	AUX
ajbspi-84390	86	22	less	less	ADV
ajbspi-84390	86	23	robust	robust	ADJ
ajbspi-84390	86	24	.	.	PUNCT
ajbspi-84390	87	1	to	to	PART
ajbspi-84390	87	2	address	address	VERB
ajbspi-84390	87	3	this	this	DET
ajbspi-84390	87	4	variability	variability	NOUN
ajbspi-84390	87	5	,	,	PUNCT
ajbspi-84390	87	6	future	future	ADJ
ajbspi-84390	87	7	studies	study	NOUN
ajbspi-84390	87	8	could	could	AUX
ajbspi-84390	87	9	explore	explore	VERB
ajbspi-84390	87	10	the	the	DET
ajbspi-84390	87	11	impact	impact	NOUN
ajbspi-84390	87	12	of	of	ADP
ajbspi-84390	87	13	age	age	NOUN
ajbspi-84390	87	14	and	and	CCONJ
ajbspi-84390	87	15	source	source	NOUN
ajbspi-84390	87	16	of	of	ADP
ajbspi-84390	87	17	the	the	DET
ajbspi-84390	87	18	tissue	tissue	NOUN
ajbspi-84390	87	19	on	on	ADP
ajbspi-84390	87	20	cell	cell	NOUN
ajbspi-84390	87	21	culture	culture	NOUN
ajbspi-84390	87	22	outcomes	outcome	NOUN
ajbspi-84390	87	23	.	.	PUNCT
ajbspi-84390	88	1	2	2	X
ajbspi-84390	88	2	.	.	X
ajbspi-84390	88	3	characterization	characterization	NOUN
ajbspi-84390	88	4	of	of	ADP
ajbspi-84390	88	5	cultured	cultured	ADJ
ajbspi-84390	88	6	rpe	rpe	PROPN
ajbspi-84390	88	7	cells	cell	NOUN
ajbspi-84390	88	8	the	the	DET
ajbspi-84390	88	9	success	success	NOUN
ajbspi-84390	88	10	of	of	ADP
ajbspi-84390	88	11	this	this	DET
ajbspi-84390	88	12	protocol	protocol	NOUN
ajbspi-84390	88	13	was	be	AUX
ajbspi-84390	88	14	further	far	ADV
ajbspi-84390	88	15	demonstrated	demonstrate	VERB
ajbspi-84390	88	16	through	through	ADP
ajbspi-84390	88	17	the	the	DET
ajbspi-84390	88	18	characterization	characterization	NOUN
ajbspi-84390	88	19	of	of	ADP
ajbspi-84390	88	20	the	the	DET
ajbspi-84390	88	21	cultured	cultured	ADJ
ajbspi-84390	88	22	cells	cell	NOUN
ajbspi-84390	88	23	.	.	PUNCT
ajbspi-84390	89	1	the	the	DET
ajbspi-84390	89	2	rpe	rpe	PROPN
ajbspi-84390	89	3	cells	cell	NOUN
ajbspi-84390	89	4	maintained	maintain	VERB
ajbspi-84390	89	5	characteristic	characteristic	ADJ
ajbspi-84390	89	6	features	feature	NOUN
ajbspi-84390	89	7	,	,	PUNCT
ajbspi-84390	89	8	including	include	VERB
ajbspi-84390	89	9	a	a	DET
ajbspi-84390	89	10	polygonal	polygonal	ADJ
ajbspi-84390	89	11	morphology	morphology	NOUN
ajbspi-84390	89	12	,	,	PUNCT
ajbspi-84390	89	13	which	which	PRON
ajbspi-84390	89	14	is	be	AUX
ajbspi-84390	89	15	typical	typical	ADJ
ajbspi-84390	89	16	of	of	ADP
ajbspi-84390	89	17	rpe	rpe	PROPN
ajbspi-84390	89	18	cells	cell	NOUN
ajbspi-84390	89	19	in	in	ADP
ajbspi-84390	89	20	vivo	vivo	NOUN
ajbspi-84390	89	21	.	.	PUNCT
ajbspi-84390	90	1	these	these	DET
ajbspi-84390	90	2	cells	cell	NOUN
ajbspi-84390	90	3	also	also	ADV
ajbspi-84390	90	4	expressed	express	VERB
ajbspi-84390	90	5	rpe	rpe	PROPN
ajbspi-84390	90	6	-	-	PUNCT
ajbspi-84390	90	7	specific	specific	ADJ
ajbspi-84390	90	8	markers	marker	NOUN
ajbspi-84390	90	9	such	such	ADJ
ajbspi-84390	90	10	as	as	ADP
ajbspi-84390	90	11	bestrophin	bestrophin	PROPN
ajbspi-84390	90	12	,	,	PUNCT
ajbspi-84390	90	13	pax6	pax6	NOUN
ajbspi-84390	90	14	,	,	PUNCT
ajbspi-84390	90	15	and	and	CCONJ
ajbspi-84390	90	16	zo-1	zo-1	NUM
ajbspi-84390	90	17	,	,	PUNCT
ajbspi-84390	90	18	confirming	confirm	VERB
ajbspi-84390	90	19	their	their	PRON
ajbspi-84390	90	20	identity	identity	NOUN
ajbspi-84390	90	21	as	as	ADP
ajbspi-84390	90	22	rpe	rpe	PROPN
ajbspi-84390	90	23	cells	cell	NOUN
ajbspi-84390	90	24	.	.	PUNCT
ajbspi-84390	91	1	bestrophin	bestrophin	PROPN
ajbspi-84390	91	2	is	be	AUX
ajbspi-84390	91	3	a	a	DET
ajbspi-84390	91	4	well	well	ADV
ajbspi-84390	91	5	-	-	PUNCT
ajbspi-84390	91	6	known	know	VERB
ajbspi-84390	91	7	marker	marker	NOUN
ajbspi-84390	91	8	of	of	ADP
ajbspi-84390	91	9	differentiated	differentiate	VERB
ajbspi-84390	91	10	rpe	rpe	PROPN
ajbspi-84390	91	11	cells	cell	NOUN
ajbspi-84390	91	12	and	and	CCONJ
ajbspi-84390	91	13	is	be	AUX
ajbspi-84390	91	14	involved	involve	VERB
ajbspi-84390	91	15	in	in	ADP
ajbspi-84390	91	16	chloride	chloride	NOUN
ajbspi-84390	91	17	channel	channel	NOUN
ajbspi-84390	91	18	regulation	regulation	NOUN
ajbspi-84390	91	19	,	,	PUNCT
ajbspi-84390	91	20	whereas	whereas	SCONJ
ajbspi-84390	91	21	pax6	pax6	PROPN
ajbspi-84390	91	22	is	be	AUX
ajbspi-84390	91	23	a	a	DET
ajbspi-84390	91	24	transcription	transcription	NOUN
ajbspi-84390	91	25	factor	factor	NOUN
ajbspi-84390	91	26	associated	associate	VERB
ajbspi-84390	91	27	with	with	ADP
ajbspi-84390	91	28	rpe	rpe	PROPN
ajbspi-84390	91	29	development	development	NOUN
ajbspi-84390	91	30	,	,	PUNCT
ajbspi-84390	91	31	and	and	CCONJ
ajbspi-84390	91	32	zo-1	zo-1	NUM
ajbspi-84390	91	33	is	be	AUX
ajbspi-84390	91	34	a	a	DET
ajbspi-84390	91	35	protein	protein	NOUN
ajbspi-84390	91	36	involved	involve	VERB
ajbspi-84390	91	37	in	in	ADP
ajbspi-84390	91	38	tight	tight	ADJ
ajbspi-84390	91	39	junction	junction	NOUN
ajbspi-84390	91	40	formation	formation	NOUN
ajbspi-84390	91	41	.	.	PUNCT
ajbspi-84390	92	1	the	the	DET
ajbspi-84390	92	2	expression	expression	NOUN
ajbspi-84390	92	3	of	of	ADP
ajbspi-84390	92	4	these	these	DET
ajbspi-84390	92	5	markers	marker	NOUN
ajbspi-84390	92	6	indicates	indicate	VERB
ajbspi-84390	92	7	that	that	SCONJ
ajbspi-84390	92	8	the	the	DET
ajbspi-84390	92	9	isolated	isolated	ADJ
ajbspi-84390	92	10	cells	cell	NOUN
ajbspi-84390	92	11	retained	retain	VERB
ajbspi-84390	92	12	their	their	PRON
ajbspi-84390	92	13	molecular	molecular	ADJ
ajbspi-84390	92	14	identity	identity	NOUN
ajbspi-84390	92	15	and	and	CCONJ
ajbspi-84390	92	16	were	be	AUX
ajbspi-84390	92	17	able	able	ADJ
ajbspi-84390	92	18	to	to	PART
ajbspi-84390	92	19	differentiate	differentiate	VERB
ajbspi-84390	92	20	into	into	ADP
ajbspi-84390	92	21	functional	functional	ADJ
ajbspi-84390	92	22	rpe	rpe	PROPN
ajbspi-84390	92	23	cells	cell	NOUN
ajbspi-84390	92	24	.	.	PUNCT
ajbspi-84390	93	1	this	this	DET
ajbspi-84390	93	2	finding	finding	NOUN
ajbspi-84390	93	3	is	be	AUX
ajbspi-84390	93	4	significant	significant	ADJ
ajbspi-84390	93	5	because	because	SCONJ
ajbspi-84390	93	6	it	it	PRON
ajbspi-84390	93	7	confirms	confirm	VERB
ajbspi-84390	93	8	that	that	SCONJ
ajbspi-84390	93	9	the	the	DET
ajbspi-84390	93	10	isolated	isolated	ADJ
ajbspi-84390	93	11	porcine	porcine	NOUN
ajbspi-84390	93	12	rpe	rpe	PROPN
ajbspi-84390	93	13	cells	cell	NOUN
ajbspi-84390	93	14	could	could	AUX
ajbspi-84390	93	15	be	be	AUX
ajbspi-84390	93	16	used	use	VERB
ajbspi-84390	93	17	for	for	ADP
ajbspi-84390	93	18	downstream	downstream	ADJ
ajbspi-84390	93	19	experiments	experiment	NOUN
ajbspi-84390	93	20	requiring	require	VERB
ajbspi-84390	93	21	a	a	DET
ajbspi-84390	93	22	differentiated	differentiated	ADJ
ajbspi-84390	93	23	and	and	CCONJ
ajbspi-84390	93	24	functional	functional	ADJ
ajbspi-84390	93	25	rpe	rpe	PROPN
ajbspi-84390	93	26	model	model	NOUN
ajbspi-84390	93	27	.	.	PUNCT
ajbspi-84390	94	1	these	these	DET
ajbspi-84390	94	2	cells	cell	NOUN
ajbspi-84390	94	3	could	could	AUX
ajbspi-84390	94	4	be	be	AUX
ajbspi-84390	94	5	useful	useful	ADJ
ajbspi-84390	94	6	in	in	ADP
ajbspi-84390	94	7	studying	study	VERB
ajbspi-84390	94	8	disease	disease	NOUN
ajbspi-84390	94	9	processes	process	NOUN
ajbspi-84390	94	10	such	such	ADJ
ajbspi-84390	94	11	as	as	ADP
ajbspi-84390	94	12	macular	macular	ADJ
ajbspi-84390	94	13	degeneration	degeneration	NOUN
ajbspi-84390	94	14	,	,	PUNCT
ajbspi-84390	94	15	as	as	ADV
ajbspi-84390	94	16	well	well	ADV
ajbspi-84390	94	17	as	as	ADP
ajbspi-84390	94	18	for	for	ADP
ajbspi-84390	94	19	testing	test	VERB
ajbspi-84390	94	20	new	new	ADJ
ajbspi-84390	94	21	drugs	drug	NOUN
ajbspi-84390	94	22	or	or	CCONJ
ajbspi-84390	94	23	interventions	intervention	NOUN
ajbspi-84390	94	24	that	that	PRON
ajbspi-84390	94	25	aim	aim	VERB
ajbspi-84390	94	26	to	to	PART
ajbspi-84390	94	27	restore	restore	VERB
ajbspi-84390	94	28	rpe	rpe	PROPN
ajbspi-84390	94	29	function	function	NOUN
ajbspi-84390	94	30	.	.	PUNCT
ajbspi-84390	95	1	furthermore	furthermore	ADV
ajbspi-84390	95	2	,	,	PUNCT
ajbspi-84390	95	3	the	the	DET
ajbspi-84390	95	4	phagocytosis	phagocytosis	NOUN
ajbspi-84390	95	5	assay	assay	NOUN
ajbspi-84390	95	6	demonstrated	demonstrate	VERB
ajbspi-84390	95	7	that	that	SCONJ
ajbspi-84390	95	8	the	the	DET
ajbspi-84390	95	9	cultured	cultured	ADJ
ajbspi-84390	95	10	rpe	rpe	PROPN
ajbspi-84390	95	11	cells	cell	NOUN
ajbspi-84390	95	12	were	be	AUX
ajbspi-84390	95	13	capable	capable	ADJ
ajbspi-84390	95	14	of	of	ADP
ajbspi-84390	95	15	ingesting	ingest	VERB
ajbspi-84390	95	16	photoreceptor	photoreceptor	NOUN
ajbspi-84390	95	17	outer	outer	ADJ
ajbspi-84390	95	18	segment	segment	NOUN
ajbspi-84390	95	19	-	-	PUNCT
ajbspi-84390	95	20	like	like	ADJ
ajbspi-84390	95	21	particles	particle	NOUN
ajbspi-84390	95	22	,	,	PUNCT
ajbspi-84390	95	23	an	an	DET
ajbspi-84390	95	24	essential	essential	ADJ
ajbspi-84390	95	25	function	function	NOUN
ajbspi-84390	95	26	of	of	ADP
ajbspi-84390	95	27	rpe	rpe	PROPN
ajbspi-84390	95	28	cells	cell	NOUN
ajbspi-84390	95	29	in	in	ADP
ajbspi-84390	95	30	vivo	vivo	NOUN
ajbspi-84390	95	31	.	.	PUNCT
ajbspi-84390	96	1	the	the	DET
ajbspi-84390	96	2	ability	ability	NOUN
ajbspi-84390	96	3	to	to	PART
ajbspi-84390	96	4	perform	perform	VERB
ajbspi-84390	96	5	this	this	DET
ajbspi-84390	96	6	key	key	ADJ
ajbspi-84390	96	7	function	function	NOUN
ajbspi-84390	96	8	is	be	AUX
ajbspi-84390	96	9	critical	critical	ADJ
ajbspi-84390	96	10	for	for	ADP
ajbspi-84390	96	11	using	use	VERB
ajbspi-84390	96	12	these	these	DET
ajbspi-84390	96	13	cells	cell	NOUN
ajbspi-84390	96	14	in	in	ADP
ajbspi-84390	96	15	disease	disease	NOUN
ajbspi-84390	96	16	modeling	modeling	NOUN
ajbspi-84390	96	17	,	,	PUNCT
ajbspi-84390	96	18	as	as	SCONJ
ajbspi-84390	96	19	defects	defect	NOUN
ajbspi-84390	96	20	in	in	ADP
ajbspi-84390	96	21	rpe	rpe	PROPN
ajbspi-84390	96	22	phagocytosis	phagocytosis	NOUN
ajbspi-84390	96	23	are	be	AUX
ajbspi-84390	96	24	central	central	ADJ
ajbspi-84390	96	25	to	to	ADP
ajbspi-84390	96	26	several	several	ADJ
ajbspi-84390	96	27	retinal	retinal	ADJ
ajbspi-84390	96	28	diseases	disease	NOUN
ajbspi-84390	96	29	,	,	PUNCT
ajbspi-84390	96	30	including	include	VERB
ajbspi-84390	96	31	amd	amd	NOUN
ajbspi-84390	96	32	.	.	PUNCT
ajbspi-84390	97	1	the	the	DET
ajbspi-84390	97	2	presence	presence	NOUN
ajbspi-84390	97	3	of	of	ADP
ajbspi-84390	97	4	functional	functional	ADJ
ajbspi-84390	97	5	rpe	rpe	PROPN
ajbspi-84390	97	6	cells	cell	NOUN
ajbspi-84390	97	7	in	in	ADP
ajbspi-84390	97	8	vitro	vitro	X
ajbspi-84390	97	9	provides	provide	VERB
ajbspi-84390	97	10	a	a	DET
ajbspi-84390	97	11	valuable	valuable	ADJ
ajbspi-84390	97	12	platform	platform	NOUN
ajbspi-84390	97	13	for	for	ADP
ajbspi-84390	97	14	studying	study	VERB
ajbspi-84390	97	15	how	how	SCONJ
ajbspi-84390	97	16	rpe	rpe	PROPN
ajbspi-84390	97	17	dysfunction	dysfunction	NOUN
ajbspi-84390	97	18	contributes	contribute	VERB
ajbspi-84390	97	19	to	to	ADP
ajbspi-84390	97	20	retinal	retinal	ADJ
ajbspi-84390	97	21	disease	disease	NOUN
ajbspi-84390	97	22	progression	progression	NOUN
ajbspi-84390	97	23	.	.	PUNCT
ajbspi-84390	98	1	the	the	DET
ajbspi-84390	98	2	transepithelial	transepithelial	ADJ
ajbspi-84390	98	3	resistance	resistance	NOUN
ajbspi-84390	98	4	(	(	PUNCT
ajbspi-84390	98	5	ter	ter	NOUN
ajbspi-84390	98	6	)	)	PUNCT
ajbspi-84390	98	7	measurements	measurement	NOUN
ajbspi-84390	98	8	indicated	indicate	VERB
ajbspi-84390	98	9	that	that	SCONJ
ajbspi-84390	98	10	the	the	DET
ajbspi-84390	98	11	cultured	cultured	ADJ
ajbspi-84390	98	12	rpe	rpe	PROPN
ajbspi-84390	98	13	cells	cell	NOUN
ajbspi-84390	98	14	formed	form	VERB
ajbspi-84390	98	15	a	a	DET
ajbspi-84390	98	16	monolayer	monolayer	NOUN
ajbspi-84390	98	17	with	with	ADP
ajbspi-84390	98	18	functional	functional	ADJ
ajbspi-84390	98	19	barrier	barrier	NOUN
ajbspi-84390	98	20	properties	property	NOUN
ajbspi-84390	98	21	.	.	PUNCT
ajbspi-84390	99	1	ter	ter	NOUN
ajbspi-84390	99	2	is	be	AUX
ajbspi-84390	99	3	commonly	commonly	ADV
ajbspi-84390	99	4	used	use	VERB
ajbspi-84390	99	5	as	as	ADP
ajbspi-84390	99	6	an	an	DET
ajbspi-84390	99	7	indicator	indicator	NOUN
ajbspi-84390	99	8	of	of	ADP
ajbspi-84390	99	9	the	the	DET
ajbspi-84390	99	10	integrity	integrity	NOUN
ajbspi-84390	99	11	of	of	ADP
ajbspi-84390	99	12	tight	tight	ADJ
ajbspi-84390	99	13	junctions	junction	NOUN
ajbspi-84390	99	14	between	between	ADP
ajbspi-84390	99	15	rpe	rpe	PROPN
ajbspi-84390	99	16	cells	cell	NOUN
ajbspi-84390	99	17	,	,	PUNCT
ajbspi-84390	99	18	and	and	CCONJ
ajbspi-84390	99	19	the	the	DET
ajbspi-84390	99	20	increase	increase	NOUN
ajbspi-84390	99	21	in	in	ADP
ajbspi-84390	99	22	ter	ter	NOUN
ajbspi-84390	99	23	over	over	ADP
ajbspi-84390	99	24	time	time	NOUN
ajbspi-84390	99	25	suggests	suggest	VERB
ajbspi-84390	99	26	that	that	SCONJ
ajbspi-84390	99	27	the	the	DET
ajbspi-84390	99	28	cells	cell	NOUN
ajbspi-84390	99	29	were	be	AUX
ajbspi-84390	99	30	establishing	establish	VERB
ajbspi-84390	99	31	tight	tight	ADJ
ajbspi-84390	99	32	junctions	junction	NOUN
ajbspi-84390	99	33	and	and	CCONJ
ajbspi-84390	99	34	becoming	become	VERB
ajbspi-84390	99	35	increasingly	increasingly	ADV
ajbspi-84390	99	36	differentiated	differentiate	VERB
ajbspi-84390	99	37	.	.	PUNCT
ajbspi-84390	100	1	this	this	DET
ajbspi-84390	100	2	result	result	NOUN
ajbspi-84390	100	3	is	be	AUX
ajbspi-84390	100	4	particularly	particularly	ADV
ajbspi-84390	100	5	important	important	ADJ
ajbspi-84390	100	6	when	when	SCONJ
ajbspi-84390	100	7	studying	study	VERB
ajbspi-84390	100	8	the	the	DET
ajbspi-84390	100	9	blood	blood	NOUN
ajbspi-84390	100	10	-	-	PUNCT
ajbspi-84390	100	11	retinal	retinal	ADJ
ajbspi-84390	100	12	barrier	barrier	NOUN
ajbspi-84390	100	13	,	,	PUNCT
ajbspi-84390	100	14	which	which	PRON
ajbspi-84390	100	15	plays	play	VERB
ajbspi-84390	100	16	a	a	DET
ajbspi-84390	100	17	crucial	crucial	ADJ
ajbspi-84390	100	18	role	role	NOUN
ajbspi-84390	100	19	in	in	ADP
ajbspi-84390	100	20	maintaining	maintain	VERB
ajbspi-84390	100	21	retinal	retinal	ADJ
ajbspi-84390	100	22	homeostasis	homeostasis	NOUN
ajbspi-84390	100	23	and	and	CCONJ
ajbspi-84390	100	24	preventing	prevent	VERB
ajbspi-84390	100	25	the	the	DET
ajbspi-84390	100	26	entry	entry	NOUN
ajbspi-84390	100	27	of	of	ADP
ajbspi-84390	100	28	harmful	harmful	ADJ
ajbspi-84390	100	29	substances	substance	NOUN
ajbspi-84390	100	30	into	into	ADP
ajbspi-84390	100	31	the	the	DET
ajbspi-84390	100	32	retina	retina	NOUN
ajbspi-84390	100	33	.	.	PUNCT
ajbspi-84390	101	1	3	3	X
ajbspi-84390	101	2	.	.	X
ajbspi-84390	101	3	challenges	challenge	NOUN
ajbspi-84390	101	4	and	and	CCONJ
ajbspi-84390	101	5	limitations	limitation	NOUN
ajbspi-84390	101	6	although	although	SCONJ
ajbspi-84390	101	7	this	this	DET
ajbspi-84390	101	8	protocol	protocol	NOUN
ajbspi-84390	101	9	was	be	AUX
ajbspi-84390	101	10	successful	successful	ADJ
ajbspi-84390	101	11	in	in	ADP
ajbspi-84390	101	12	producing	produce	VERB
ajbspi-84390	101	13	a	a	DET
ajbspi-84390	101	14	consistent	consistent	ADJ
ajbspi-84390	101	15	,	,	PUNCT
ajbspi-84390	101	16	high	high	ADJ
ajbspi-84390	101	17	-	-	PUNCT
ajbspi-84390	101	18	quality	quality	NOUN
ajbspi-84390	101	19	rpe	rpe	PROPN
ajbspi-84390	101	20	cell	cell	NOUN
ajbspi-84390	101	21	culture	culture	NOUN
ajbspi-84390	101	22	,	,	PUNCT
ajbspi-84390	101	23	several	several	ADJ
ajbspi-84390	101	24	challenges	challenge	NOUN
ajbspi-84390	101	25	remain	remain	VERB
ajbspi-84390	101	26	that	that	PRON
ajbspi-84390	101	27	could	could	AUX
ajbspi-84390	101	28	affect	affect	VERB
ajbspi-84390	101	29	the	the	DET
ajbspi-84390	101	30	broad	broad	ADJ
ajbspi-84390	101	31	adoption	adoption	NOUN
ajbspi-84390	101	32	of	of	ADP
ajbspi-84390	101	33	this	this	DET
ajbspi-84390	101	34	protocol	protocol	NOUN
ajbspi-84390	101	35	.	.	PUNCT
ajbspi-84390	102	1	one	one	NUM
ajbspi-84390	102	2	significant	significant	ADJ
ajbspi-84390	102	3	challenge	challenge	NOUN
ajbspi-84390	102	4	is	be	AUX
ajbspi-84390	102	5	the	the	DET
ajbspi-84390	102	6	timesensitive	timesensitive	ADJ
ajbspi-84390	102	7	nature	nature	NOUN
ajbspi-84390	102	8	of	of	ADP
ajbspi-84390	102	9	the	the	DET
ajbspi-84390	102	10	tissue	tissue	NOUN
ajbspi-84390	102	11	dissection	dissection	NOUN
ajbspi-84390	102	12	.	.	PUNCT
ajbspi-84390	103	1	since	since	SCONJ
ajbspi-84390	103	2	the	the	DET
ajbspi-84390	103	3	porcine	porcine	NOUN
ajbspi-84390	103	4	eyes	eye	NOUN
ajbspi-84390	103	5	were	be	AUX
ajbspi-84390	103	6	obtained	obtain	VERB
ajbspi-84390	103	7	from	from	ADP
ajbspi-84390	103	8	a	a	DET
ajbspi-84390	103	9	local	local	ADJ
ajbspi-84390	103	10	abattoir	abattoir	NOUN
ajbspi-84390	103	11	,	,	PUNCT
ajbspi-84390	103	12	there	there	PRON
ajbspi-84390	103	13	is	be	VERB
ajbspi-84390	103	14	always	always	ADV
ajbspi-84390	103	15	a	a	DET
ajbspi-84390	103	16	limited	limited	ADJ
ajbspi-84390	103	17	window	window	NOUN
ajbspi-84390	103	18	of	of	ADP
ajbspi-84390	103	19	time	time	NOUN
ajbspi-84390	103	20	in	in	ADP
ajbspi-84390	103	21	which	which	PRON
ajbspi-84390	103	22	the	the	DET
ajbspi-84390	103	23	tissue	tissue	NOUN
ajbspi-84390	103	24	must	must	AUX
ajbspi-84390	103	25	be	be	AUX
ajbspi-84390	103	26	processed	process	VERB
ajbspi-84390	103	27	to	to	PART
ajbspi-84390	103	28	prevent	prevent	VERB
ajbspi-84390	103	29	degradation	degradation	NOUN
ajbspi-84390	103	30	or	or	CCONJ
ajbspi-84390	103	31	loss	loss	NOUN
ajbspi-84390	103	32	of	of	ADP
ajbspi-84390	103	33	cell	cell	NOUN
ajbspi-84390	103	34	viability	viability	NOUN
ajbspi-84390	103	35	.	.	PUNCT
ajbspi-84390	104	1	the	the	DET
ajbspi-84390	104	2	need	need	NOUN
ajbspi-84390	104	3	for	for	ADP
ajbspi-84390	104	4	fresh	fresh	ADJ
ajbspi-84390	104	5	tissue	tissue	NOUN
ajbspi-84390	104	6	means	mean	VERB
ajbspi-84390	104	7	that	that	SCONJ
ajbspi-84390	104	8	the	the	DET
ajbspi-84390	104	9	protocol	protocol	NOUN
ajbspi-84390	104	10	is	be	AUX
ajbspi-84390	104	11	best	well	ADV
ajbspi-84390	104	12	suited	suit	VERB
ajbspi-84390	104	13	for	for	ADP
ajbspi-84390	104	14	use	use	NOUN
ajbspi-84390	104	15	in	in	ADP
ajbspi-84390	104	16	laboratories	laboratory	NOUN
ajbspi-84390	104	17	with	with	ADP
ajbspi-84390	104	18	easy	easy	ADJ
ajbspi-84390	104	19	access	access	NOUN
ajbspi-84390	104	20	to	to	ADP
ajbspi-84390	104	21	porcine	porcine	NOUN
ajbspi-84390	104	22	tissue	tissue	NOUN
ajbspi-84390	104	23	sources	source	NOUN
ajbspi-84390	104	24	or	or	CCONJ
ajbspi-84390	104	25	for	for	ADP
ajbspi-84390	104	26	collaborative	collaborative	ADJ
ajbspi-84390	104	27	efforts	effort	NOUN
ajbspi-84390	104	28	with	with	ADP
ajbspi-84390	104	29	abattoirs	abattoir	NOUN
ajbspi-84390	104	30	or	or	CCONJ
ajbspi-84390	104	31	suppliers	supplier	NOUN
ajbspi-84390	104	32	who	who	PRON
ajbspi-84390	104	33	can	can	AUX
ajbspi-84390	104	34	provide	provide	VERB
ajbspi-84390	104	35	high	high	ADJ
ajbspi-84390	104	36	-	-	PUNCT
ajbspi-84390	104	37	quality	quality	NOUN
ajbspi-84390	104	38	tissue	tissue	NOUN
ajbspi-84390	104	39	on	on	ADP
ajbspi-84390	104	40	demand	demand	NOUN
ajbspi-84390	104	41	.	.	PUNCT
ajbspi-84390	105	1	another	another	DET
ajbspi-84390	105	2	challenge	challenge	NOUN
ajbspi-84390	105	3	is	be	AUX
ajbspi-84390	105	4	the	the	DET
ajbspi-84390	105	5	variability	variability	NOUN
ajbspi-84390	105	6	in	in	ADP
ajbspi-84390	105	7	cell	cell	NOUN
ajbspi-84390	105	8	growth	growth	NOUN
ajbspi-84390	105	9	depending	depend	VERB
ajbspi-84390	105	10	on	on	ADP
ajbspi-84390	105	11	the	the	DET
ajbspi-84390	105	12	donor	donor	NOUN
ajbspi-84390	105	13	's	's	PART
ajbspi-84390	105	14	health	health	NOUN
ajbspi-84390	105	15	and	and	CCONJ
ajbspi-84390	105	16	age	age	NOUN
ajbspi-84390	105	17	.	.	PUNCT
ajbspi-84390	106	1	although	although	SCONJ
ajbspi-84390	106	2	the	the	DET
ajbspi-84390	106	3	cells	cell	NOUN
ajbspi-84390	106	4	cultured	cultured	ADJ
ajbspi-84390	106	5	in	in	ADP
ajbspi-84390	106	6	this	this	DET
ajbspi-84390	106	7	study	study	NOUN
ajbspi-84390	106	8	showed	show	VERB
ajbspi-84390	106	9	good	good	ADJ
ajbspi-84390	106	10	proliferative	proliferative	ADJ
ajbspi-84390	106	11	potential	potential	NOUN
ajbspi-84390	106	12	,	,	PUNCT
ajbspi-84390	106	13	researchers	researcher	NOUN
ajbspi-84390	106	14	must	must	AUX
ajbspi-84390	106	15	be	be	AUX
ajbspi-84390	106	16	aware	aware	ADJ
ajbspi-84390	106	17	that	that	SCONJ
ajbspi-84390	106	18	age	age	NOUN
ajbspi-84390	106	19	,	,	PUNCT
ajbspi-84390	106	20	tissue	tissue	NOUN
ajbspi-84390	106	21	quality	quality	NOUN
ajbspi-84390	106	22	,	,	PUNCT
ajbspi-84390	106	23	and	and	CCONJ
ajbspi-84390	106	24	even	even	ADV
ajbspi-84390	106	25	differences	difference	NOUN
ajbspi-84390	106	26	in	in	ADP
ajbspi-84390	106	27	harvesting	harvesting	NOUN
ajbspi-84390	106	28	techniques	technique	NOUN
ajbspi-84390	106	29	can	can	AUX
ajbspi-84390	106	30	affect	affect	VERB
ajbspi-84390	106	31	the	the	DET
ajbspi-84390	106	32	results	result	NOUN
ajbspi-84390	106	33	.	.	PUNCT
ajbspi-84390	107	1	developing	develop	VERB
ajbspi-84390	107	2	protocols	protocol	NOUN
ajbspi-84390	107	3	that	that	PRON
ajbspi-84390	107	4	account	account	VERB
ajbspi-84390	107	5	for	for	ADP
ajbspi-84390	107	6	such	such	ADJ
ajbspi-84390	107	7	variability	variability	NOUN
ajbspi-84390	107	8	and	and	CCONJ
ajbspi-84390	107	9	improving	improve	VERB
ajbspi-84390	107	10	standardization	standardization	NOUN
ajbspi-84390	107	11	for	for	ADP
ajbspi-84390	107	12	different	different	ADJ
ajbspi-84390	107	13	tissue	tissue	NOUN
ajbspi-84390	107	14	sources	source	NOUN
ajbspi-84390	107	15	could	could	AUX
ajbspi-84390	107	16	help	help	VERB
ajbspi-84390	107	17	address	address	VERB
ajbspi-84390	107	18	these	these	DET
ajbspi-84390	107	19	issues	issue	NOUN
ajbspi-84390	107	20	.	.	PUNCT
ajbspi-84390	108	1	additionally	additionally	ADV
ajbspi-84390	108	2	,	,	PUNCT
ajbspi-84390	108	3	while	while	SCONJ
ajbspi-84390	108	4	this	this	DET
ajbspi-84390	108	5	protocol	protocol	NOUN
ajbspi-84390	108	6	was	be	AUX
ajbspi-84390	108	7	able	able	ADJ
ajbspi-84390	108	8	to	to	PART
ajbspi-84390	108	9	generate	generate	VERB
ajbspi-84390	108	10	functional	functional	ADJ
ajbspi-84390	108	11	rpe	rpe	PROPN
ajbspi-84390	108	12	cells	cell	NOUN
ajbspi-84390	108	13	for	for	ADP
ajbspi-84390	108	14	experimental	experimental	ADJ
ajbspi-84390	108	15	purposes	purpose	NOUN
ajbspi-84390	108	16	,	,	PUNCT
ajbspi-84390	108	17	longterm	longterm	VERB
ajbspi-84390	108	18	culture	culture	NOUN
ajbspi-84390	108	19	of	of	ADP
ajbspi-84390	108	20	rpe	rpe	PROPN
ajbspi-84390	108	21	cells	cell	NOUN
ajbspi-84390	108	22	in	in	ADP
ajbspi-84390	108	23	vitro	vitro	X
ajbspi-84390	108	24	remains	remain	VERB
ajbspi-84390	108	25	a	a	DET
ajbspi-84390	108	26	challenge	challenge	NOUN
ajbspi-84390	108	27	.	.	PUNCT
ajbspi-84390	109	1	rpe	rpe	PROPN
ajbspi-84390	109	2	cells	cell	NOUN
ajbspi-84390	109	3	are	be	AUX
ajbspi-84390	109	4	known	know	VERB
ajbspi-84390	109	5	to	to	PART
ajbspi-84390	109	6	undergo	undergo	VERB
ajbspi-84390	109	7	senescence	senescence	NOUN
ajbspi-84390	109	8	after	after	ADP
ajbspi-84390	109	9	prolonged	prolonged	ADJ
ajbspi-84390	109	10	culture	culture	NOUN
ajbspi-84390	109	11	,	,	PUNCT
ajbspi-84390	109	12	and	and	CCONJ
ajbspi-84390	109	13	their	their	PRON
ajbspi-84390	109	14	function	function	NOUN
ajbspi-84390	109	15	may	may	AUX
ajbspi-84390	109	16	deteriorate	deteriorate	VERB
ajbspi-84390	109	17	over	over	ADP
ajbspi-84390	109	18	time	time	NOUN
ajbspi-84390	109	19	.	.	PUNCT
ajbspi-84390	110	1	future	future	ADJ
ajbspi-84390	110	2	work	work	NOUN
ajbspi-84390	110	3	may	may	AUX
ajbspi-84390	110	4	focus	focus	VERB
ajbspi-84390	110	5	on	on	ADP
ajbspi-84390	110	6	extending	extend	VERB
ajbspi-84390	110	7	the	the	DET
ajbspi-84390	110	8	longevity	longevity	NOUN
ajbspi-84390	110	9	of	of	ADP
ajbspi-84390	110	10	these	these	DET
ajbspi-84390	110	11	cultures	culture	NOUN
ajbspi-84390	110	12	,	,	PUNCT
ajbspi-84390	110	13	either	either	CCONJ
ajbspi-84390	110	14	through	through	ADP
ajbspi-84390	110	15	genetic	genetic	ADJ
ajbspi-84390	110	16	manipulation	manipulation	NOUN
ajbspi-84390	110	17	or	or	CCONJ
ajbspi-84390	110	18	by	by	ADP
ajbspi-84390	110	19	modifying	modify	VERB
ajbspi-84390	110	20	the	the	DET
ajbspi-84390	110	21	culture	culture	NOUN
ajbspi-84390	110	22	medium	medium	NOUN
ajbspi-84390	110	23	to	to	PART
ajbspi-84390	110	24	better	well	ADV
ajbspi-84390	110	25	support	support	VERB
ajbspi-84390	110	26	long	long	ADJ
ajbspi-84390	110	27	-	-	PUNCT
ajbspi-84390	110	28	term	term	NOUN
ajbspi-84390	110	29	cell	cell	NOUN
ajbspi-84390	110	30	viability	viability	NOUN
ajbspi-84390	110	31	.	.	PUNCT
ajbspi-84390	111	1	moreover	moreover	ADV
ajbspi-84390	111	2	,	,	PUNCT
ajbspi-84390	111	3	the	the	DET
ajbspi-84390	111	4	use	use	NOUN
ajbspi-84390	111	5	of	of	ADP
ajbspi-84390	111	6	3d	3d	NUM
ajbspi-84390	111	7	culture	culture	NOUN
ajbspi-84390	111	8	models	model	NOUN
ajbspi-84390	111	9	or	or	CCONJ
ajbspi-84390	111	10	organoids	organoid	NOUN
ajbspi-84390	111	11	could	could	AUX
ajbspi-84390	111	12	help	help	VERB
ajbspi-84390	111	13	replicate	replicate	VERB
ajbspi-84390	111	14	the	the	DET
ajbspi-84390	111	15	native	native	ADJ
ajbspi-84390	111	16	architecture	architecture	NOUN
ajbspi-84390	111	17	and	and	CCONJ
ajbspi-84390	111	18	function	function	NOUN
ajbspi-84390	111	19	of	of	ADP
ajbspi-84390	111	20	rpe	rpe	PROPN
ajbspi-84390	111	21	cells	cell	NOUN
ajbspi-84390	111	22	more	more	ADV
ajbspi-84390	111	23	closely	closely	ADV
ajbspi-84390	111	24	than	than	ADP
ajbspi-84390	111	25	conventional	conventional	ADJ
ajbspi-84390	111	26	2d	2d	NUM
ajbspi-84390	111	27	monolayers	monolayer	NOUN
ajbspi-84390	111	28	.	.	PUNCT
ajbspi-84390	112	1	4	4	X
ajbspi-84390	112	2	.	.	X
ajbspi-84390	112	3	implications	implication	NOUN
ajbspi-84390	112	4	for	for	ADP
ajbspi-84390	112	5	future	future	ADJ
ajbspi-84390	112	6	research	research	NOUN
ajbspi-84390	112	7	this	this	DET
ajbspi-84390	112	8	validated	validate	VERB
ajbspi-84390	112	9	protocol	protocol	NOUN
ajbspi-84390	112	10	opens	open	VERB
ajbspi-84390	112	11	up	up	ADP
ajbspi-84390	112	12	new	new	ADJ
ajbspi-84390	112	13	avenues	avenue	NOUN
ajbspi-84390	112	14	for	for	ADP
ajbspi-84390	112	15	retinal	retinal	ADJ
ajbspi-84390	112	16	research	research	NOUN
ajbspi-84390	112	17	,	,	PUNCT
ajbspi-84390	112	18	particularly	particularly	ADV
ajbspi-84390	112	19	in	in	ADP
ajbspi-84390	112	20	the	the	DET
ajbspi-84390	112	21	study	study	NOUN
ajbspi-84390	112	22	of	of	ADP
ajbspi-84390	112	23	retinal	retinal	ADJ
ajbspi-84390	112	24	diseases	disease	NOUN
ajbspi-84390	112	25	and	and	CCONJ
ajbspi-84390	112	26	the	the	DET
ajbspi-84390	112	27	development	development	NOUN
ajbspi-84390	112	28	of	of	ADP
ajbspi-84390	112	29	therapies	therapy	NOUN
ajbspi-84390	112	30	.	.	PUNCT
ajbspi-84390	113	1	retinal	retinal	ADJ
ajbspi-84390	113	2	degeneration	degeneration	NOUN
ajbspi-84390	113	3	models	model	NOUN
ajbspi-84390	113	4	,	,	PUNCT
ajbspi-84390	113	5	such	such	ADJ
ajbspi-84390	113	6	as	as	ADP
ajbspi-84390	113	7	those	those	PRON
ajbspi-84390	113	8	for	for	ADP
ajbspi-84390	113	9	amd	amd	ADJ
ajbspi-84390	113	10	or	or	CCONJ
ajbspi-84390	113	11	diabetic	diabetic	ADJ
ajbspi-84390	113	12	retinopathy	retinopathy	NOUN
ajbspi-84390	113	13	,	,	PUNCT
ajbspi-84390	113	14	could	could	AUX
ajbspi-84390	113	15	benefit	benefit	VERB
ajbspi-84390	113	16	from	from	ADP
ajbspi-84390	113	17	the	the	DET
ajbspi-84390	113	18	use	use	NOUN
ajbspi-84390	113	19	of	of	ADP
ajbspi-84390	113	20	porcine	porcine	ADJ
ajbspi-84390	113	21	rpe	rpe	PROPN
ajbspi-84390	113	22	cells	cell	NOUN
ajbspi-84390	113	23	,	,	PUNCT
ajbspi-84390	113	24	as	as	SCONJ
ajbspi-84390	113	25	they	they	PRON
ajbspi-84390	113	26	provide	provide	VERB
ajbspi-84390	113	27	a	a	DET
ajbspi-84390	113	28	more	more	ADV
ajbspi-84390	113	29	accurate	accurate	ADJ
ajbspi-84390	113	30	representation	representation	NOUN
ajbspi-84390	113	31	of	of	ADP
ajbspi-84390	113	32	human	human	ADJ
ajbspi-84390	113	33	retinal	retinal	ADJ
ajbspi-84390	113	34	biology	biology	NOUN
ajbspi-84390	113	35	compared	compare	VERB
ajbspi-84390	113	36	to	to	ADP
ajbspi-84390	113	37	other	other	ADJ
ajbspi-84390	113	38	models	model	NOUN
ajbspi-84390	113	39	,	,	PUNCT
ajbspi-84390	113	40	such	such	ADJ
ajbspi-84390	113	41	as	as	ADP
ajbspi-84390	113	42	mouse	mouse	NOUN
ajbspi-84390	113	43	or	or	CCONJ
ajbspi-84390	113	44	human	human	ADJ
ajbspi-84390	113	45	cell	cell	NOUN
ajbspi-84390	113	46	lines	line	NOUN
ajbspi-84390	113	47	.	.	PUNCT
ajbspi-84390	114	1	furthermore	furthermore	ADV
ajbspi-84390	114	2	,	,	PUNCT
ajbspi-84390	114	3	the	the	DET
ajbspi-84390	114	4	reproducibility	reproducibility	NOUN
ajbspi-84390	114	5	of	of	ADP
ajbspi-84390	114	6	this	this	DET
ajbspi-84390	114	7	protocol	protocol	NOUN
ajbspi-84390	114	8	makes	make	VERB
ajbspi-84390	114	9	it	it	PRON
ajbspi-84390	114	10	an	an	DET
ajbspi-84390	114	11	excellent	excellent	ADJ
ajbspi-84390	114	12	platform	platform	NOUN
ajbspi-84390	114	13	for	for	ADP
ajbspi-84390	114	14	drug	drug	NOUN
ajbspi-84390	114	15	screening	screening	NOUN
ajbspi-84390	114	16	and	and	CCONJ
ajbspi-84390	114	17	gene	gene	NOUN
ajbspi-84390	114	18	american	american	PROPN
ajbspi-84390	114	19	journal	journal	PROPN
ajbspi-84390	114	20	of	of	ADP
ajbspi-84390	114	21	applied	apply	VERB
ajbspi-84390	114	22	science	science	NOUN
ajbspi-84390	114	23	and	and	CCONJ
ajbspi-84390	114	24	technology	technology	NOUN
ajbspi-84390	114	25	5	5	NUM
ajbspi-84390	114	26	https://theusajournals.com/index.php/ajast	https://theusajournals.com/index.php/ajast	NOUN
ajbspi-84390	114	27	american	american	PROPN
ajbspi-84390	114	28	journal	journal	PROPN
ajbspi-84390	114	29	of	of	ADP
ajbspi-84390	114	30	applied	apply	VERB
ajbspi-84390	114	31	science	science	NOUN
ajbspi-84390	114	32	and	and	CCONJ
ajbspi-84390	114	33	technology	technology	NOUN
ajbspi-84390	114	34	(	(	PUNCT
ajbspi-84390	114	35	issn	issn	PROPN
ajbspi-84390	114	36	:	:	PUNCT
ajbspi-84390	114	37	2771	2771	NUM
ajbspi-84390	114	38	-	-	SYM
ajbspi-84390	114	39	2745	2745	NUM
ajbspi-84390	114	40	)	)	PUNCT
ajbspi-84390	114	41	therapy	therapy	NOUN
ajbspi-84390	114	42	studies	study	NOUN
ajbspi-84390	114	43	aimed	aim	VERB
ajbspi-84390	114	44	at	at	ADP
ajbspi-84390	114	45	restoring	restore	VERB
ajbspi-84390	114	46	rpe	rpe	PROPN
ajbspi-84390	114	47	function	function	NOUN
ajbspi-84390	114	48	.	.	PUNCT
ajbspi-84390	115	1	given	give	VERB
ajbspi-84390	115	2	the	the	DET
ajbspi-84390	115	3	role	role	NOUN
ajbspi-84390	115	4	of	of	ADP
ajbspi-84390	115	5	rpe	rpe	PROPN
ajbspi-84390	115	6	cells	cell	NOUN
ajbspi-84390	115	7	in	in	ADP
ajbspi-84390	115	8	retinal	retinal	ADJ
ajbspi-84390	115	9	diseases	disease	NOUN
ajbspi-84390	115	10	,	,	PUNCT
ajbspi-84390	115	11	the	the	DET
ajbspi-84390	115	12	ability	ability	NOUN
ajbspi-84390	115	13	to	to	PART
ajbspi-84390	115	14	culture	culture	VERB
ajbspi-84390	115	15	these	these	DET
ajbspi-84390	115	16	cells	cell	NOUN
ajbspi-84390	115	17	in	in	ADP
ajbspi-84390	115	18	vitro	vitro	X
ajbspi-84390	115	19	allows	allow	VERB
ajbspi-84390	115	20	researchers	researcher	NOUN
ajbspi-84390	115	21	to	to	PART
ajbspi-84390	115	22	test	test	VERB
ajbspi-84390	115	23	potential	potential	ADJ
ajbspi-84390	115	24	therapeutic	therapeutic	ADJ
ajbspi-84390	115	25	interventions	intervention	NOUN
ajbspi-84390	115	26	targeting	target	VERB
ajbspi-84390	115	27	rpe	rpe	PROPN
ajbspi-84390	115	28	cells	cell	NOUN
ajbspi-84390	115	29	,	,	PUNCT
ajbspi-84390	115	30	such	such	ADJ
ajbspi-84390	115	31	as	as	ADP
ajbspi-84390	115	32	gene	gene	NOUN
ajbspi-84390	115	33	editing	editing	NOUN
ajbspi-84390	115	34	or	or	CCONJ
ajbspi-84390	115	35	stem	stem	VERB
ajbspi-84390	115	36	cell	cell	NOUN
ajbspi-84390	115	37	-	-	PUNCT
ajbspi-84390	115	38	based	base	VERB
ajbspi-84390	115	39	therapies	therapy	NOUN
ajbspi-84390	115	40	.	.	PUNCT
ajbspi-84390	116	1	additionally	additionally	ADV
ajbspi-84390	116	2	,	,	PUNCT
ajbspi-84390	116	3	the	the	DET
ajbspi-84390	116	4	use	use	NOUN
ajbspi-84390	116	5	of	of	ADP
ajbspi-84390	116	6	porcine	porcine	NOUN
ajbspi-84390	116	7	rpe	rpe	PROPN
ajbspi-84390	116	8	cells	cell	NOUN
ajbspi-84390	116	9	could	could	AUX
ajbspi-84390	116	10	facilitate	facilitate	VERB
ajbspi-84390	116	11	the	the	DET
ajbspi-84390	116	12	development	development	NOUN
ajbspi-84390	116	13	of	of	ADP
ajbspi-84390	116	14	personalized	personalized	ADJ
ajbspi-84390	116	15	medicine	medicine	NOUN
ajbspi-84390	116	16	for	for	ADP
ajbspi-84390	116	17	retinal	retinal	ADJ
ajbspi-84390	116	18	diseases	disease	NOUN
ajbspi-84390	116	19	,	,	PUNCT
ajbspi-84390	116	20	as	as	SCONJ
ajbspi-84390	116	21	patient	patient	NOUN
ajbspi-84390	116	22	-	-	PUNCT
ajbspi-84390	116	23	specific	specific	ADJ
ajbspi-84390	116	24	models	model	NOUN
ajbspi-84390	116	25	can	can	AUX
ajbspi-84390	116	26	be	be	AUX
ajbspi-84390	116	27	generated	generate	VERB
ajbspi-84390	116	28	using	use	VERB
ajbspi-84390	116	29	induced	induce	VERB
ajbspi-84390	116	30	pluripotent	pluripotent	ADJ
ajbspi-84390	116	31	stem	stem	NOUN
ajbspi-84390	116	32	cells	cell	NOUN
ajbspi-84390	116	33	(	(	PUNCT
ajbspi-84390	116	34	ipscs	ipscs	NOUN
ajbspi-84390	116	35	)	)	PUNCT
ajbspi-84390	116	36	differentiated	differentiate	VERB
ajbspi-84390	116	37	into	into	ADP
ajbspi-84390	116	38	rpe	rpe	PROPN
ajbspi-84390	116	39	cells	cell	NOUN
ajbspi-84390	116	40	,	,	PUNCT
ajbspi-84390	116	41	providing	provide	VERB
ajbspi-84390	116	42	a	a	DET
ajbspi-84390	116	43	platform	platform	NOUN
ajbspi-84390	116	44	for	for	ADP
ajbspi-84390	116	45	testing	test	VERB
ajbspi-84390	116	46	drug	drug	NOUN
ajbspi-84390	116	47	responses	response	NOUN
ajbspi-84390	116	48	or	or	CCONJ
ajbspi-84390	116	49	gene	gene	NOUN
ajbspi-84390	116	50	therapies	therapy	NOUN
ajbspi-84390	116	51	tailored	tailor	VERB
ajbspi-84390	116	52	to	to	ADP
ajbspi-84390	116	53	individual	individual	ADJ
ajbspi-84390	116	54	patients	patient	NOUN
ajbspi-84390	116	55	.	.	PUNCT
ajbspi-84390	117	1	finally	finally	ADV
ajbspi-84390	117	2	,	,	PUNCT
ajbspi-84390	117	3	this	this	DET
ajbspi-84390	117	4	protocol	protocol	NOUN
ajbspi-84390	117	5	could	could	AUX
ajbspi-84390	117	6	also	also	ADV
ajbspi-84390	117	7	serve	serve	VERB
ajbspi-84390	117	8	as	as	ADP
ajbspi-84390	117	9	a	a	DET
ajbspi-84390	117	10	foundation	foundation	NOUN
ajbspi-84390	117	11	for	for	ADP
ajbspi-84390	117	12	studying	study	VERB
ajbspi-84390	117	13	rpe	rpe	PROPN
ajbspi-84390	117	14	cell	cell	NOUN
ajbspi-84390	117	15	transplantation	transplantation	NOUN
ajbspi-84390	117	16	as	as	ADP
ajbspi-84390	117	17	a	a	DET
ajbspi-84390	117	18	potential	potential	ADJ
ajbspi-84390	117	19	therapy	therapy	NOUN
ajbspi-84390	117	20	for	for	ADP
ajbspi-84390	117	21	retinal	retinal	ADJ
ajbspi-84390	117	22	degenerative	degenerative	ADJ
ajbspi-84390	117	23	diseases	disease	NOUN
ajbspi-84390	117	24	.	.	PUNCT
ajbspi-84390	118	1	rpe	rpe	PROPN
ajbspi-84390	118	2	transplantation	transplantation	NOUN
ajbspi-84390	118	3	has	have	AUX
ajbspi-84390	118	4	shown	show	VERB
ajbspi-84390	118	5	promise	promise	NOUN
ajbspi-84390	118	6	in	in	ADP
ajbspi-84390	118	7	preclinical	preclinical	ADJ
ajbspi-84390	118	8	and	and	CCONJ
ajbspi-84390	118	9	clinical	clinical	ADJ
ajbspi-84390	118	10	studies	study	NOUN
ajbspi-84390	118	11	as	as	ADP
ajbspi-84390	118	12	a	a	DET
ajbspi-84390	118	13	strategy	strategy	NOUN
ajbspi-84390	118	14	to	to	PART
ajbspi-84390	118	15	restore	restore	VERB
ajbspi-84390	118	16	vision	vision	NOUN
ajbspi-84390	118	17	,	,	PUNCT
ajbspi-84390	118	18	and	and	CCONJ
ajbspi-84390	118	19	this	this	DET
ajbspi-84390	118	20	protocol	protocol	NOUN
ajbspi-84390	118	21	could	could	AUX
ajbspi-84390	118	22	be	be	AUX
ajbspi-84390	118	23	used	use	VERB
ajbspi-84390	118	24	to	to	PART
ajbspi-84390	118	25	better	well	ADV
ajbspi-84390	118	26	understand	understand	VERB
ajbspi-84390	118	27	the	the	DET
ajbspi-84390	118	28	biological	biological	ADJ
ajbspi-84390	118	29	mechanisms	mechanism	NOUN
ajbspi-84390	118	30	underlying	underlie	VERB
ajbspi-84390	118	31	successful	successful	ADJ
ajbspi-84390	118	32	rpe	rpe	PROPN
ajbspi-84390	118	33	transplantation	transplantation	NOUN
ajbspi-84390	118	34	and	and	CCONJ
ajbspi-84390	118	35	engraftment	engraftment	NOUN
ajbspi-84390	118	36	.	.	PUNCT
ajbspi-84390	119	1	5	5	X
ajbspi-84390	119	2	.	.	X
ajbspi-84390	119	3	future	future	ADJ
ajbspi-84390	119	4	directions	direction	NOUN
ajbspi-84390	119	5	looking	look	VERB
ajbspi-84390	119	6	ahead	ahead	ADV
ajbspi-84390	119	7	,	,	PUNCT
ajbspi-84390	119	8	further	far	ADV
ajbspi-84390	119	9	refinement	refinement	NOUN
ajbspi-84390	119	10	of	of	ADP
ajbspi-84390	119	11	the	the	DET
ajbspi-84390	119	12	protocol	protocol	NOUN
ajbspi-84390	119	13	could	could	AUX
ajbspi-84390	119	14	focus	focus	VERB
ajbspi-84390	119	15	on	on	ADP
ajbspi-84390	119	16	optimizing	optimize	VERB
ajbspi-84390	119	17	the	the	DET
ajbspi-84390	119	18	culture	culture	NOUN
ajbspi-84390	119	19	conditions	condition	NOUN
ajbspi-84390	119	20	to	to	PART
ajbspi-84390	119	21	improve	improve	VERB
ajbspi-84390	119	22	the	the	DET
ajbspi-84390	119	23	long	long	ADJ
ajbspi-84390	119	24	-	-	PUNCT
ajbspi-84390	119	25	term	term	NOUN
ajbspi-84390	119	26	viability	viability	NOUN
ajbspi-84390	119	27	and	and	CCONJ
ajbspi-84390	119	28	functional	functional	ADJ
ajbspi-84390	119	29	preservation	preservation	NOUN
ajbspi-84390	119	30	of	of	ADP
ajbspi-84390	119	31	the	the	DET
ajbspi-84390	119	32	rpe	rpe	PROPN
ajbspi-84390	119	33	cells	cell	NOUN
ajbspi-84390	119	34	.	.	PUNCT
ajbspi-84390	120	1	developing	develop	VERB
ajbspi-84390	120	2	methods	method	NOUN
ajbspi-84390	120	3	to	to	PART
ajbspi-84390	120	4	maintain	maintain	VERB
ajbspi-84390	120	5	the	the	DET
ajbspi-84390	120	6	cells	cell	NOUN
ajbspi-84390	120	7	in	in	ADP
ajbspi-84390	120	8	a	a	DET
ajbspi-84390	120	9	more	more	ADV
ajbspi-84390	120	10	native	native	ADJ
ajbspi-84390	120	11	-	-	PUNCT
ajbspi-84390	120	12	like	like	ADJ
ajbspi-84390	120	13	state	state	NOUN
ajbspi-84390	120	14	for	for	ADP
ajbspi-84390	120	15	longer	long	ADJ
ajbspi-84390	120	16	periods	period	NOUN
ajbspi-84390	120	17	would	would	AUX
ajbspi-84390	120	18	be	be	AUX
ajbspi-84390	120	19	beneficial	beneficial	ADJ
ajbspi-84390	120	20	for	for	ADP
ajbspi-84390	120	21	studying	study	VERB
ajbspi-84390	120	22	chronic	chronic	ADJ
ajbspi-84390	120	23	diseases	disease	NOUN
ajbspi-84390	120	24	and	and	CCONJ
ajbspi-84390	120	25	for	for	ADP
ajbspi-84390	120	26	long	long	ADJ
ajbspi-84390	120	27	-	-	PUNCT
ajbspi-84390	120	28	term	term	NOUN
ajbspi-84390	120	29	therapeutic	therapeutic	ADJ
ajbspi-84390	120	30	interventions	intervention	NOUN
ajbspi-84390	120	31	.	.	PUNCT
ajbspi-84390	121	1	additionally	additionally	ADV
ajbspi-84390	121	2	,	,	PUNCT
ajbspi-84390	121	3	exploring	explore	VERB
ajbspi-84390	121	4	the	the	DET
ajbspi-84390	121	5	use	use	NOUN
ajbspi-84390	121	6	of	of	ADP
ajbspi-84390	121	7	3d	3d	NUM
ajbspi-84390	121	8	culture	culture	NOUN
ajbspi-84390	121	9	systems	system	NOUN
ajbspi-84390	121	10	and	and	CCONJ
ajbspi-84390	121	11	bioreactor	bioreactor	NOUN
ajbspi-84390	121	12	technologies	technology	NOUN
ajbspi-84390	121	13	could	could	AUX
ajbspi-84390	121	14	allow	allow	VERB
ajbspi-84390	121	15	researchers	researcher	NOUN
ajbspi-84390	121	16	to	to	PART
ajbspi-84390	121	17	recreate	recreate	VERB
ajbspi-84390	121	18	the	the	DET
ajbspi-84390	121	19	three	three	NUM
ajbspi-84390	121	20	-	-	PUNCT
ajbspi-84390	121	21	dimensional	dimensional	ADJ
ajbspi-84390	121	22	architecture	architecture	NOUN
ajbspi-84390	121	23	of	of	ADP
ajbspi-84390	121	24	the	the	DET
ajbspi-84390	121	25	retina	retina	NOUN
ajbspi-84390	121	26	,	,	PUNCT
ajbspi-84390	121	27	providing	provide	VERB
ajbspi-84390	121	28	a	a	DET
ajbspi-84390	121	29	more	more	ADV
ajbspi-84390	121	30	physiologically	physiologically	ADV
ajbspi-84390	121	31	relevant	relevant	ADJ
ajbspi-84390	121	32	model	model	NOUN
ajbspi-84390	121	33	for	for	ADP
ajbspi-84390	121	34	studying	study	VERB
ajbspi-84390	121	35	rpe	rpe	PROPN
ajbspi-84390	121	36	cell	cell	NOUN
ajbspi-84390	121	37	behavior	behavior	NOUN
ajbspi-84390	121	38	and	and	CCONJ
ajbspi-84390	121	39	function	function	NOUN
ajbspi-84390	121	40	in	in	ADP
ajbspi-84390	121	41	health	health	NOUN
ajbspi-84390	121	42	and	and	CCONJ
ajbspi-84390	121	43	disease	disease	NOUN
ajbspi-84390	121	44	.	.	PUNCT
ajbspi-84390	122	1	furthermore	furthermore	ADV
ajbspi-84390	122	2	,	,	PUNCT
ajbspi-84390	122	3	genetic	genetic	ADJ
ajbspi-84390	122	4	modification	modification	NOUN
ajbspi-84390	122	5	techniques	technique	NOUN
ajbspi-84390	122	6	,	,	PUNCT
ajbspi-84390	122	7	such	such	ADJ
ajbspi-84390	122	8	as	as	ADP
ajbspi-84390	122	9	crispr	crispr	NOUN
ajbspi-84390	122	10	-	-	PUNCT
ajbspi-84390	122	11	cas9	cas9	NOUN
ajbspi-84390	122	12	,	,	PUNCT
ajbspi-84390	122	13	could	could	AUX
ajbspi-84390	122	14	be	be	AUX
ajbspi-84390	122	15	applied	apply	VERB
ajbspi-84390	122	16	to	to	ADP
ajbspi-84390	122	17	these	these	DET
ajbspi-84390	122	18	cultures	culture	NOUN
ajbspi-84390	122	19	to	to	PART
ajbspi-84390	122	20	study	study	VERB
ajbspi-84390	122	21	the	the	DET
ajbspi-84390	122	22	impact	impact	NOUN
ajbspi-84390	122	23	of	of	ADP
ajbspi-84390	122	24	specific	specific	ADJ
ajbspi-84390	122	25	genes	gene	NOUN
ajbspi-84390	122	26	on	on	ADP
ajbspi-84390	122	27	rpe	rpe	PROPN
ajbspi-84390	122	28	cell	cell	NOUN
ajbspi-84390	122	29	function	function	NOUN
ajbspi-84390	122	30	and	and	CCONJ
ajbspi-84390	122	31	disease	disease	NOUN
ajbspi-84390	122	32	progression	progression	NOUN
ajbspi-84390	122	33	,	,	PUNCT
ajbspi-84390	122	34	potentially	potentially	ADV
ajbspi-84390	122	35	leading	lead	VERB
ajbspi-84390	122	36	to	to	ADP
ajbspi-84390	122	37	new	new	ADJ
ajbspi-84390	122	38	insights	insight	NOUN
ajbspi-84390	122	39	into	into	ADP
ajbspi-84390	122	40	the	the	DET
ajbspi-84390	122	41	molecular	molecular	ADJ
ajbspi-84390	122	42	mechanisms	mechanism	NOUN
ajbspi-84390	122	43	of	of	ADP
ajbspi-84390	122	44	retinal	retinal	ADJ
ajbspi-84390	122	45	diseases	disease	NOUN
ajbspi-84390	122	46	.	.	PUNCT
ajbspi-84390	123	1	in	in	ADP
ajbspi-84390	123	2	conclusion	conclusion	NOUN
ajbspi-84390	123	3	,	,	PUNCT
ajbspi-84390	123	4	this	this	DET
ajbspi-84390	123	5	study	study	NOUN
ajbspi-84390	123	6	provides	provide	VERB
ajbspi-84390	123	7	a	a	DET
ajbspi-84390	123	8	robust	robust	ADJ
ajbspi-84390	123	9	,	,	PUNCT
ajbspi-84390	123	10	validated	validated	ADJ
ajbspi-84390	123	11	,	,	PUNCT
ajbspi-84390	123	12	and	and	CCONJ
ajbspi-84390	123	13	reproducible	reproducible	VERB
ajbspi-84390	123	14	protocol	protocol	NOUN
ajbspi-84390	123	15	for	for	ADP
ajbspi-84390	123	16	culturing	culture	VERB
ajbspi-84390	123	17	porcine	porcine	NOUN
ajbspi-84390	123	18	rpe	rpe	PROPN
ajbspi-84390	123	19	cells	cell	NOUN
ajbspi-84390	123	20	that	that	PRON
ajbspi-84390	123	21	can	can	AUX
ajbspi-84390	123	22	be	be	AUX
ajbspi-84390	123	23	used	use	VERB
ajbspi-84390	123	24	in	in	ADP
ajbspi-84390	123	25	a	a	DET
ajbspi-84390	123	26	wide	wide	ADJ
ajbspi-84390	123	27	variety	variety	NOUN
ajbspi-84390	123	28	of	of	ADP
ajbspi-84390	123	29	retinal	retinal	ADJ
ajbspi-84390	123	30	research	research	NOUN
ajbspi-84390	123	31	applications	application	NOUN
ajbspi-84390	123	32	.	.	PUNCT
ajbspi-84390	124	1	by	by	ADP
ajbspi-84390	124	2	providing	provide	VERB
ajbspi-84390	124	3	a	a	DET
ajbspi-84390	124	4	standardized	standardized	ADJ
ajbspi-84390	124	5	approach	approach	NOUN
ajbspi-84390	124	6	,	,	PUNCT
ajbspi-84390	124	7	this	this	DET
ajbspi-84390	124	8	protocol	protocol	NOUN
ajbspi-84390	124	9	will	will	AUX
ajbspi-84390	124	10	enhance	enhance	VERB
ajbspi-84390	124	11	the	the	DET
ajbspi-84390	124	12	consistency	consistency	NOUN
ajbspi-84390	124	13	and	and	CCONJ
ajbspi-84390	124	14	reproducibility	reproducibility	NOUN
ajbspi-84390	124	15	of	of	ADP
ajbspi-84390	124	16	experiments	experiment	NOUN
ajbspi-84390	124	17	across	across	ADP
ajbspi-84390	124	18	laboratories	laboratory	NOUN
ajbspi-84390	124	19	and	and	CCONJ
ajbspi-84390	124	20	enable	enable	VERB
ajbspi-84390	124	21	new	new	ADJ
ajbspi-84390	124	22	avenues	avenue	NOUN
ajbspi-84390	124	23	of	of	ADP
ajbspi-84390	124	24	research	research	NOUN
ajbspi-84390	124	25	into	into	ADP
ajbspi-84390	124	26	retinal	retinal	ADJ
ajbspi-84390	124	27	diseases	disease	NOUN
ajbspi-84390	124	28	,	,	PUNCT
ajbspi-84390	124	29	therapeutic	therapeutic	ADJ
ajbspi-84390	124	30	interventions	intervention	NOUN
ajbspi-84390	124	31	,	,	PUNCT
ajbspi-84390	124	32	and	and	CCONJ
ajbspi-84390	124	33	regenerative	regenerative	ADJ
ajbspi-84390	124	34	medicine	medicine	NOUN
ajbspi-84390	124	35	.	.	PUNCT
ajbspi-84390	125	1	conclusion	conclusion	NOUN
ajbspi-84390	125	2	in	in	ADP
ajbspi-84390	125	3	conclusion	conclusion	NOUN
ajbspi-84390	125	4	,	,	PUNCT
ajbspi-84390	125	5	this	this	DET
ajbspi-84390	125	6	article	article	NOUN
ajbspi-84390	125	7	provides	provide	VERB
ajbspi-84390	125	8	a	a	DET
ajbspi-84390	125	9	validated	validated	ADJ
ajbspi-84390	125	10	and	and	CCONJ
ajbspi-84390	125	11	reproducible	reproducible	ADJ
ajbspi-84390	125	12	protocol	protocol	NOUN
ajbspi-84390	125	13	for	for	ADP
ajbspi-84390	125	14	culturing	culture	VERB
ajbspi-84390	125	15	single	single	ADJ
ajbspi-84390	125	16	-	-	PUNCT
ajbspi-84390	125	17	eye	eye	NOUN
ajbspi-84390	125	18	porcine	porcine	NOUN
ajbspi-84390	125	19	rpe	rpe	PROPN
ajbspi-84390	125	20	cells	cell	NOUN
ajbspi-84390	125	21	,	,	PUNCT
ajbspi-84390	125	22	which	which	PRON
ajbspi-84390	125	23	can	can	AUX
ajbspi-84390	125	24	serve	serve	VERB
ajbspi-84390	125	25	as	as	ADP
ajbspi-84390	125	26	a	a	DET
ajbspi-84390	125	27	valuable	valuable	ADJ
ajbspi-84390	125	28	resource	resource	NOUN
ajbspi-84390	125	29	for	for	ADP
ajbspi-84390	125	30	researchers	researcher	NOUN
ajbspi-84390	125	31	investigating	investigate	VERB
ajbspi-84390	125	32	retinal	retinal	ADJ
ajbspi-84390	125	33	diseases	disease	NOUN
ajbspi-84390	125	34	and	and	CCONJ
ajbspi-84390	125	35	therapies	therapy	NOUN
ajbspi-84390	125	36	.	.	PUNCT
ajbspi-84390	126	1	the	the	DET
ajbspi-84390	126	2	protocol	protocol	NOUN
ajbspi-84390	126	3	ensures	ensure	VERB
ajbspi-84390	126	4	the	the	DET
ajbspi-84390	126	5	isolation	isolation	NOUN
ajbspi-84390	126	6	of	of	ADP
ajbspi-84390	126	7	highquality	highquality	NOUN
ajbspi-84390	126	8	rpe	rpe	PROPN
ajbspi-84390	126	9	cells	cell	NOUN
ajbspi-84390	126	10	with	with	ADP
ajbspi-84390	126	11	preserved	preserve	VERB
ajbspi-84390	126	12	morphology	morphology	NOUN
ajbspi-84390	126	13	,	,	PUNCT
ajbspi-84390	126	14	functionality	functionality	NOUN
ajbspi-84390	126	15	,	,	PUNCT
ajbspi-84390	126	16	and	and	CCONJ
ajbspi-84390	126	17	barrier	barrier	NOUN
ajbspi-84390	126	18	properties	property	NOUN
ajbspi-84390	126	19	,	,	PUNCT
ajbspi-84390	126	20	making	make	VERB
ajbspi-84390	126	21	it	it	PRON
ajbspi-84390	126	22	suitable	suitable	ADJ
ajbspi-84390	126	23	for	for	ADP
ajbspi-84390	126	24	a	a	DET
ajbspi-84390	126	25	wide	wide	ADJ
ajbspi-84390	126	26	range	range	NOUN
ajbspi-84390	126	27	of	of	ADP
ajbspi-84390	126	28	retinal	retinal	ADJ
ajbspi-84390	126	29	studies	study	NOUN
ajbspi-84390	126	30	.	.	PUNCT
ajbspi-84390	127	1	by	by	ADP
ajbspi-84390	127	2	providing	provide	VERB
ajbspi-84390	127	3	a	a	DET
ajbspi-84390	127	4	standardized	standardized	ADJ
ajbspi-84390	127	5	and	and	CCONJ
ajbspi-84390	127	6	reliable	reliable	ADJ
ajbspi-84390	127	7	methodology	methodology	NOUN
ajbspi-84390	127	8	,	,	PUNCT
ajbspi-84390	127	9	this	this	DET
ajbspi-84390	127	10	work	work	NOUN
ajbspi-84390	127	11	contributes	contribute	VERB
ajbspi-84390	127	12	to	to	ADP
ajbspi-84390	127	13	advancing	advance	VERB
ajbspi-84390	127	14	retinal	retinal	ADJ
ajbspi-84390	127	15	research	research	NOUN
ajbspi-84390	127	16	and	and	CCONJ
ajbspi-84390	127	17	improving	improve	VERB
ajbspi-84390	127	18	experimental	experimental	ADJ
ajbspi-84390	127	19	consistency	consistency	NOUN
ajbspi-84390	127	20	across	across	ADP
ajbspi-84390	127	21	laboratories	laboratory	NOUN
ajbspi-84390	127	22	.	.	PUNCT
ajbspi-84390	128	1	references	reference	NOUN
ajbspi-84390	128	2	wong	wong	PROPN
ajbspi-84390	128	3	,	,	PUNCT
ajbspi-84390	128	4	w.l	w.l	PROPN
ajbspi-84390	128	5	.	.	PROPN
ajbspi-84390	128	6	;	;	PUNCT
ajbspi-84390	128	7	su	su	PROPN
ajbspi-84390	128	8	,	,	PUNCT
ajbspi-84390	128	9	x.	x.	PROPN
ajbspi-84390	128	10	;	;	PUNCT
ajbspi-84390	128	11	li	li	PROPN
ajbspi-84390	128	12	,	,	PUNCT
ajbspi-84390	128	13	x.	x.	PROPN
ajbspi-84390	128	14	;	;	PUNCT
ajbspi-84390	128	15	cheung	cheung	PROPN
ajbspi-84390	128	16	,	,	PUNCT
ajbspi-84390	128	17	c.m.g	c.m.g	NOUN
ajbspi-84390	128	18	.	.	PUNCT
ajbspi-84390	128	19	;	;	PUNCT
ajbspi-84390	129	1	klein	klein	PROPN
ajbspi-84390	129	2	,	,	PUNCT
ajbspi-84390	129	3	r.	r.	PROPN
ajbspi-84390	129	4	;	;	PUNCT
ajbspi-84390	129	5	cheng	cheng	PROPN
ajbspi-84390	129	6	,	,	PUNCT
ajbspi-84390	129	7	c.-y	c.-y	NOUN
ajbspi-84390	129	8	.	.	PUNCT
ajbspi-84390	129	9	;	;	PUNCT
ajbspi-84390	129	10	wong	wong	PROPN
ajbspi-84390	129	11	,	,	PUNCT
ajbspi-84390	129	12	t.y	t.y	PROPN
ajbspi-84390	129	13	.	.	PROPN
ajbspi-84390	129	14	global	global	ADJ
ajbspi-84390	129	15	prevalence	prevalence	NOUN
ajbspi-84390	129	16	of	of	ADP
ajbspi-84390	129	17	agerelated	agerelate	VERB
ajbspi-84390	129	18	macular	macular	ADJ
ajbspi-84390	129	19	degeneration	degeneration	NOUN
ajbspi-84390	129	20	and	and	CCONJ
ajbspi-84390	129	21	disease	disease	NOUN
ajbspi-84390	129	22	burden	burden	NOUN
ajbspi-84390	129	23	projection	projection	NOUN
ajbspi-84390	129	24	for	for	ADP
ajbspi-84390	129	25	2020	2020	NUM
ajbspi-84390	129	26	and	and	CCONJ
ajbspi-84390	129	27	2040	2040	NUM
ajbspi-84390	129	28	:	:	PUNCT
ajbspi-84390	129	29	a	a	DET
ajbspi-84390	129	30	systematic	systematic	ADJ
ajbspi-84390	129	31	review	review	NOUN
ajbspi-84390	129	32	and	and	CCONJ
ajbspi-84390	129	33	meta	meta	ADJ
ajbspi-84390	129	34	-	-	PUNCT
ajbspi-84390	129	35	analysis	analysis	NOUN
ajbspi-84390	129	36	.	.	PUNCT
ajbspi-84390	130	1	lancet	lancet	NOUN
ajbspi-84390	130	2	glob	glob	PROPN
ajbspi-84390	130	3	.	.	PUNCT
ajbspi-84390	131	1	health	health	PROPN
ajbspi-84390	131	2	2014	2014	NUM
ajbspi-84390	131	3	,	,	PUNCT
ajbspi-84390	131	4	2	2	NUM
ajbspi-84390	131	5	,	,	PUNCT
ajbspi-84390	131	6	e106	e106	PROPN
ajbspi-84390	131	7	–	–	PUNCT
ajbspi-84390	131	8	e116	e116	NUM
ajbspi-84390	131	9	.	.	PUNCT
ajbspi-84390	132	1	[	[	X
ajbspi-84390	132	2	google	google	NOUN
ajbspi-84390	132	3	scholar	scholar	NOUN
ajbspi-84390	132	4	]	]	PUNCT
ajbspi-84390	133	1	[	[	X
ajbspi-84390	133	2	crossref	crossref	X
ajbspi-84390	133	3	]	]	X
ajbspi-84390	133	4	[	[	X
ajbspi-84390	133	5	pubmed	pubmed	X
ajbspi-84390	133	6	]	]	PUNCT
ajbspi-84390	133	7	zając	zając	NOUN
ajbspi-84390	133	8	-	-	PUNCT
ajbspi-84390	133	9	pytrus	pytrus	NOUN
ajbspi-84390	133	10	,	,	PUNCT
ajbspi-84390	133	11	h.m	h.m	PROPN
ajbspi-84390	133	12	.	.	PROPN
ajbspi-84390	133	13	;	;	PUNCT
ajbspi-84390	133	14	pilecka	pilecka	PROPN
ajbspi-84390	133	15	,	,	PUNCT
ajbspi-84390	133	16	a.	a.	NOUN
ajbspi-84390	133	17	;	;	PUNCT
ajbspi-84390	133	18	turno	turno	PROPN
ajbspi-84390	133	19	-	-	PUNCT
ajbspi-84390	133	20	kręcicka	kręcicka	NOUN
ajbspi-84390	133	21	,	,	PUNCT
ajbspi-84390	133	22	a.	a.	NOUN
ajbspi-84390	133	23	;	;	PUNCT
ajbspi-84390	133	24	adamiec	adamiec	NOUN
ajbspi-84390	133	25	-	-	PUNCT
ajbspi-84390	133	26	mroczek	mroczek	NOUN
ajbspi-84390	133	27	,	,	PUNCT
ajbspi-84390	133	28	j.	j.	PROPN
ajbspi-84390	133	29	;	;	PUNCT
ajbspi-84390	133	30	misiuk	misiuk	NOUN
ajbspi-84390	133	31	-	-	PUNCT
ajbspi-84390	133	32	hojło	hojło	NOUN
ajbspi-84390	133	33	,	,	PUNCT
ajbspi-84390	133	34	m.	m.	NOUN
ajbspi-84390	133	35	the	the	DET
ajbspi-84390	133	36	dry	dry	ADJ
ajbspi-84390	133	37	form	form	NOUN
ajbspi-84390	133	38	of	of	ADP
ajbspi-84390	133	39	age	age	NOUN
ajbspi-84390	133	40	-	-	PUNCT
ajbspi-84390	133	41	related	relate	VERB
ajbspi-84390	133	42	macular	macular	ADJ
ajbspi-84390	133	43	degeneration	degeneration	NOUN
ajbspi-84390	133	44	(	(	PUNCT
ajbspi-84390	133	45	amd	amd	ADJ
ajbspi-84390	133	46	):	):	PUNCT
ajbspi-84390	133	47	the	the	DET
ajbspi-84390	133	48	current	current	ADJ
ajbspi-84390	133	49	concepts	concept	NOUN
ajbspi-84390	133	50	of	of	ADP
ajbspi-84390	133	51	pathogenesis	pathogenesis	NOUN
ajbspi-84390	133	52	and	and	CCONJ
ajbspi-84390	133	53	prospects	prospect	NOUN
ajbspi-84390	133	54	for	for	ADP
ajbspi-84390	133	55	treatment	treatment	NOUN
ajbspi-84390	133	56	.	.	PUNCT
ajbspi-84390	134	1	adv	adv	PROPN
ajbspi-84390	134	2	.	.	PUNCT
ajbspi-84390	135	1	clin	clin	PROPN
ajbspi-84390	135	2	.	.	PUNCT
ajbspi-84390	136	1	exp	exp	PROPN
ajbspi-84390	136	2	.	.	PROPN
ajbspi-84390	136	3	med	med	PROPN
ajbspi-84390	136	4	.	.	PROPN
ajbspi-84390	136	5	2015	2015	NUM
ajbspi-84390	136	6	,	,	PUNCT
ajbspi-84390	136	7	24	24	NUM
ajbspi-84390	136	8	,	,	PUNCT
ajbspi-84390	136	9	1099–1104	1099–1104	NUM
ajbspi-84390	136	10	.	.	PUNCT
ajbspi-84390	137	1	[	[	X
ajbspi-84390	137	2	google	google	NOUN
ajbspi-84390	137	3	scholar	scholar	NOUN
ajbspi-84390	137	4	]	]	PUNCT
ajbspi-84390	138	1	[	[	X
ajbspi-84390	138	2	crossref	crossref	X
ajbspi-84390	138	3	]	]	X
ajbspi-84390	138	4	[	[	X
ajbspi-84390	138	5	pubmed	pubmed	X
ajbspi-84390	138	6	]	]	X
ajbspi-84390	138	7	fleckenstein	fleckenstein	ADJ
ajbspi-84390	138	8	,	,	PUNCT
ajbspi-84390	138	9	m.	m.	NOUN
ajbspi-84390	138	10	;	;	PUNCT
ajbspi-84390	138	11	keenan	keenan	PROPN
ajbspi-84390	138	12	,	,	PUNCT
ajbspi-84390	138	13	t.d.l	t.d.l	PROPN
ajbspi-84390	138	14	.	.	PUNCT
ajbspi-84390	138	15	;	;	PUNCT
ajbspi-84390	138	16	guymer	guymer	NOUN
ajbspi-84390	138	17	,	,	PUNCT
ajbspi-84390	138	18	r.h	r.h	PROPN
ajbspi-84390	138	19	.	.	PROPN
ajbspi-84390	138	20	;	;	PUNCT
ajbspi-84390	138	21	chakravarthy	chakravarthy	ADJ
ajbspi-84390	138	22	,	,	PUNCT
ajbspi-84390	138	23	u.	u.	PROPN
ajbspi-84390	138	24	;	;	PUNCT
ajbspi-84390	138	25	schmitz	schmitz	PROPN
ajbspi-84390	138	26	-	-	PUNCT
ajbspi-84390	138	27	valckenberg	valckenberg	PROPN
ajbspi-84390	138	28	,	,	PUNCT
ajbspi-84390	138	29	s.	s.	PROPN
ajbspi-84390	138	30	;	;	PUNCT
ajbspi-84390	138	31	klaver	klaver	PROPN
ajbspi-84390	138	32	,	,	PUNCT
ajbspi-84390	138	33	c.c	c.c	PROPN
ajbspi-84390	138	34	.	.	PROPN
ajbspi-84390	138	35	;	;	PUNCT
ajbspi-84390	138	36	wong	wong	PROPN
ajbspi-84390	138	37	,	,	PUNCT
ajbspi-84390	138	38	w.t	w.t	PROPN
ajbspi-84390	138	39	.	.	PUNCT
ajbspi-84390	138	40	;	;	PUNCT
ajbspi-84390	138	41	chew	chew	VERB
ajbspi-84390	138	42	,	,	PUNCT
ajbspi-84390	138	43	e.y	e.y	PROPN
ajbspi-84390	138	44	.	.	PROPN
ajbspi-84390	138	45	age	age	NOUN
ajbspi-84390	138	46	-	-	PUNCT
ajbspi-84390	138	47	related	relate	VERB
ajbspi-84390	138	48	macular	macular	ADJ
ajbspi-84390	138	49	degeneration	degeneration	NOUN
ajbspi-84390	138	50	.	.	PUNCT
ajbspi-84390	139	1	nat	nat	PROPN
ajbspi-84390	139	2	.	.	PUNCT
ajbspi-84390	139	3	rev	rev	PROPN
ajbspi-84390	139	4	.	.	PUNCT
ajbspi-84390	140	1	dis	dis	PROPN
ajbspi-84390	140	2	.	.	PUNCT
ajbspi-84390	141	1	primers	primer	NOUN
ajbspi-84390	141	2	2021	2021	NUM
ajbspi-84390	141	3	,	,	PUNCT
ajbspi-84390	141	4	7	7	NUM
ajbspi-84390	141	5	,	,	PUNCT
ajbspi-84390	141	6	31	31	NUM
ajbspi-84390	141	7	.	.	PUNCT
ajbspi-84390	142	1	[	[	X
ajbspi-84390	142	2	google	google	NOUN
ajbspi-84390	142	3	scholar	scholar	NOUN
ajbspi-84390	142	4	]	]	PUNCT
ajbspi-84390	143	1	[	[	X
ajbspi-84390	143	2	crossref	crossref	X
ajbspi-84390	143	3	]	]	X
ajbspi-84390	143	4	bhutto	bhutto	PROPN
ajbspi-84390	143	5	,	,	PUNCT
ajbspi-84390	143	6	i.	i.	PROPN
ajbspi-84390	143	7	;	;	PUNCT
ajbspi-84390	143	8	lutty	lutty	PROPN
ajbspi-84390	143	9	,	,	PUNCT
ajbspi-84390	143	10	g.	g.	PROPN
ajbspi-84390	143	11	understanding	understand	VERB
ajbspi-84390	143	12	age	age	NOUN
ajbspi-84390	143	13	-	-	PUNCT
ajbspi-84390	143	14	related	relate	VERB
ajbspi-84390	143	15	macular	macular	ADJ
ajbspi-84390	143	16	degeneration	degeneration	NOUN
ajbspi-84390	143	17	(	(	PUNCT
ajbspi-84390	143	18	amd	amd	ADJ
ajbspi-84390	143	19	):	):	PUNCT
ajbspi-84390	143	20	relationships	relationship	NOUN
ajbspi-84390	143	21	between	between	ADP
ajbspi-84390	143	22	the	the	DET
ajbspi-84390	143	23	photoreceptor	photoreceptor	NOUN
ajbspi-84390	143	24	/	/	SYM
ajbspi-84390	143	25	retinal	retinal	ADJ
ajbspi-84390	143	26	pigment	pigment	NOUN
ajbspi-84390	143	27	epithelium	epithelium	NOUN
ajbspi-84390	143	28	/	/	SYM
ajbspi-84390	143	29	bruch	bruch	NOUN
ajbspi-84390	143	30	’s	’s	PART
ajbspi-84390	143	31	membrane	membrane	NOUN
ajbspi-84390	143	32	/	/	SYM
ajbspi-84390	143	33	choriocapillaris	choriocapillaris	NOUN
ajbspi-84390	143	34	complex	complex	NOUN
ajbspi-84390	143	35	.	.	PUNCT
ajbspi-84390	144	1	mol	mol	PROPN
ajbspi-84390	144	2	.	.	PUNCT
ajbspi-84390	145	1	asp	asp	PROPN
ajbspi-84390	145	2	.	.	PROPN
ajbspi-84390	145	3	med	med	PROPN
ajbspi-84390	145	4	.	.	PROPN
ajbspi-84390	145	5	2012	2012	NUM
ajbspi-84390	145	6	,	,	PUNCT
ajbspi-84390	145	7	33	33	NUM
ajbspi-84390	145	8	,	,	PUNCT
ajbspi-84390	145	9	295–317	295–317	NUM
ajbspi-84390	145	10	.	.	PUNCT
ajbspi-84390	146	1	[	[	X
ajbspi-84390	146	2	google	google	NOUN
ajbspi-84390	146	3	scholar	scholar	NOUN
ajbspi-84390	146	4	]	]	PUNCT
ajbspi-84390	147	1	[	[	X
ajbspi-84390	147	2	crossref	crossref	X
ajbspi-84390	147	3	]	]	X
ajbspi-84390	147	4	strauss	strauss	PROPN
ajbspi-84390	147	5	,	,	PUNCT
ajbspi-84390	147	6	o.	o.	NOUN
ajbspi-84390	147	7	the	the	DET
ajbspi-84390	147	8	retinal	retinal	ADJ
ajbspi-84390	147	9	pigment	pigment	NOUN
ajbspi-84390	147	10	epithelium	epithelium	NOUN
ajbspi-84390	147	11	in	in	ADP
ajbspi-84390	147	12	visual	visual	ADJ
ajbspi-84390	147	13	function	function	NOUN
ajbspi-84390	147	14	.	.	PUNCT
ajbspi-84390	148	1	physiol	physiol	PROPN
ajbspi-84390	148	2	.	.	PUNCT
ajbspi-84390	149	1	rev	rev	PROPN
ajbspi-84390	149	2	.	.	PROPN
ajbspi-84390	149	3	2005	2005	NUM
ajbspi-84390	149	4	,	,	PUNCT
ajbspi-84390	149	5	85	85	NUM
ajbspi-84390	149	6	,	,	PUNCT
ajbspi-84390	149	7	845–881	845–881	NUM
ajbspi-84390	149	8	.	.	PUNCT
ajbspi-84390	150	1	[	[	X
ajbspi-84390	150	2	google	google	NOUN
ajbspi-84390	150	3	scholar	scholar	NOUN
ajbspi-84390	150	4	]	]	PUNCT
ajbspi-84390	151	1	[	[	X
ajbspi-84390	151	2	crossref	crossref	X
ajbspi-84390	151	3	]	]	X
ajbspi-84390	151	4	aisenbrey	aisenbrey	PROPN
ajbspi-84390	151	5	,	,	PUNCT
ajbspi-84390	151	6	s.	s.	PROPN
ajbspi-84390	151	7	;	;	PUNCT
ajbspi-84390	151	8	zhang	zhang	PROPN
ajbspi-84390	151	9	,	,	PUNCT
ajbspi-84390	151	10	m.	m.	NOUN
ajbspi-84390	151	11	;	;	PUNCT
ajbspi-84390	151	12	bacher	bacher	PROPN
ajbspi-84390	151	13	,	,	PUNCT
ajbspi-84390	151	14	d.	d.	PROPN
ajbspi-84390	151	15	;	;	PUNCT
ajbspi-84390	151	16	yee	yee	PROPN
ajbspi-84390	151	17	,	,	PUNCT
ajbspi-84390	151	18	j.	j.	PROPN
ajbspi-84390	151	19	;	;	PUNCT
ajbspi-84390	151	20	brunken	brunken	PROPN
ajbspi-84390	151	21	,	,	PUNCT
ajbspi-84390	151	22	w.j	w.j	PROPN
ajbspi-84390	151	23	.	.	PROPN
ajbspi-84390	151	24	;	;	PUNCT
ajbspi-84390	152	1	hunter	hunter	NOUN
ajbspi-84390	152	2	,	,	PUNCT
ajbspi-84390	152	3	d.d	d.d	PROPN
ajbspi-84390	152	4	.	.	PROPN
ajbspi-84390	152	5	retinal	retinal	ADJ
ajbspi-84390	152	6	pigment	pigment	ADJ
ajbspi-84390	152	7	epithelial	epithelial	ADJ
ajbspi-84390	152	8	cells	cell	NOUN
ajbspi-84390	152	9	synthesize	synthesize	VERB
ajbspi-84390	152	10	laminins	laminin	NOUN
ajbspi-84390	152	11	,	,	PUNCT
ajbspi-84390	152	12	including	include	VERB
ajbspi-84390	152	13	laminin	laminin	NOUN
ajbspi-84390	152	14	5	5	NUM
ajbspi-84390	152	15	,	,	PUNCT
ajbspi-84390	152	16	and	and	CCONJ
ajbspi-84390	152	17	adhere	adhere	VERB
ajbspi-84390	152	18	to	to	ADP
ajbspi-84390	152	19	them	they	PRON
ajbspi-84390	152	20	through	through	ADP
ajbspi-84390	152	21	alpha3	alpha3	NOUN
ajbspi-84390	152	22	-	-	PUNCT
ajbspi-84390	152	23	and	and	CCONJ
ajbspi-84390	152	24	alpha6	alpha6	ADV
ajbspi-84390	152	25	-	-	PUNCT
ajbspi-84390	152	26	containing	contain	VERB
ajbspi-84390	152	27	integrins	integrin	NOUN
ajbspi-84390	152	28	.	.	PUNCT
ajbspi-84390	152	29	investig	investig	PROPN
ajbspi-84390	152	30	.	.	PUNCT
ajbspi-84390	152	31	ophthalmol	ophthalmol	PROPN
ajbspi-84390	152	32	.	.	PUNCT
ajbspi-84390	153	1	vis	vis	X
ajbspi-84390	153	2	.	.	PUNCT
ajbspi-84390	154	1	sci	sci	PROPN
ajbspi-84390	154	2	.	.	PROPN
ajbspi-84390	154	3	2006	2006	NUM
ajbspi-84390	154	4	,	,	PUNCT
ajbspi-84390	154	5	47	47	NUM
ajbspi-84390	154	6	,	,	PUNCT
ajbspi-84390	154	7	5537–5544	5537–5544	NUM
ajbspi-84390	154	8	.	.	PUNCT
ajbspi-84390	155	1	[	[	X
ajbspi-84390	155	2	google	google	NOUN
ajbspi-84390	155	3	scholar	scholar	NOUN
ajbspi-84390	155	4	]	]	PUNCT
ajbspi-84390	156	1	[	[	X
ajbspi-84390	156	2	crossref	crossref	X
ajbspi-84390	156	3	]	]	X
ajbspi-84390	156	4	schnichels	schnichel	NOUN
ajbspi-84390	156	5	,	,	PUNCT
ajbspi-84390	156	6	s.	s.	PROPN
ajbspi-84390	156	7	;	;	PUNCT
ajbspi-84390	156	8	paquet	paquet	PROPN
ajbspi-84390	156	9	-	-	PUNCT
ajbspi-84390	156	10	durand	durand	PROPN
ajbspi-84390	156	11	,	,	PUNCT
ajbspi-84390	156	12	f.	f.	PROPN
ajbspi-84390	156	13	;	;	PUNCT
ajbspi-84390	156	14	löscher	löscher	X
ajbspi-84390	156	15	,	,	PUNCT
ajbspi-84390	156	16	m.	m.	NOUN
ajbspi-84390	156	17	;	;	PUNCT
ajbspi-84390	156	18	tsai	tsai	PROPN
ajbspi-84390	156	19	,	,	PUNCT
ajbspi-84390	156	20	t.	t.	PROPN
ajbspi-84390	156	21	;	;	PUNCT
ajbspi-84390	156	22	hurst	hurst	PROPN
ajbspi-84390	156	23	,	,	PUNCT
ajbspi-84390	156	24	j.	j.	PROPN
ajbspi-84390	156	25	;	;	PUNCT
ajbspi-84390	156	26	joachim	joachim	PROPN
ajbspi-84390	156	27	,	,	PUNCT
ajbspi-84390	156	28	s.c	s.c	PROPN
ajbspi-84390	156	29	.	.	PROPN
ajbspi-84390	156	30	;	;	PUNCT
ajbspi-84390	156	31	klettner	klettner	NOUN
ajbspi-84390	156	32	,	,	PUNCT
ajbspi-84390	156	33	a.	a.	NOUN
ajbspi-84390	156	34	retina	retina	NOUN
ajbspi-84390	156	35	in	in	ADP
ajbspi-84390	156	36	a	a	DET
ajbspi-84390	156	37	dish	dish	NOUN
ajbspi-84390	156	38	:	:	PUNCT
ajbspi-84390	156	39	cell	cell	NOUN
ajbspi-84390	156	40	cultures	culture	NOUN
ajbspi-84390	156	41	,	,	PUNCT
ajbspi-84390	156	42	retinal	retinal	ADJ
ajbspi-84390	156	43	explants	explant	NOUN
ajbspi-84390	156	44	and	and	CCONJ
ajbspi-84390	156	45	animal	animal	NOUN
ajbspi-84390	156	46	models	model	NOUN
ajbspi-84390	156	47	for	for	ADP
ajbspi-84390	156	48	common	common	ADJ
ajbspi-84390	156	49	diseases	disease	NOUN
ajbspi-84390	156	50	of	of	ADP
ajbspi-84390	156	51	the	the	DET
ajbspi-84390	156	52	retina	retina	NOUN
ajbspi-84390	156	53	.	.	PUNCT
ajbspi-84390	157	1	prog	prog	NOUN
ajbspi-84390	157	2	.	.	PUNCT
ajbspi-84390	158	1	retin	retin	PROPN
ajbspi-84390	158	2	.	.	PUNCT
ajbspi-84390	159	1	eye	eye	NOUN
ajbspi-84390	159	2	res	re	NOUN
ajbspi-84390	159	3	.	.	PUNCT
ajbspi-84390	159	4	2021	2021	NUM
ajbspi-84390	159	5	,	,	PUNCT
ajbspi-84390	159	6	81	81	NUM
ajbspi-84390	159	7	,	,	PUNCT
ajbspi-84390	159	8	100880	100880	NUM
ajbspi-84390	159	9	.	.	PUNCT
ajbspi-84390	160	1	[	[	X
ajbspi-84390	160	2	google	google	NOUN
ajbspi-84390	160	3	scholar	scholar	NOUN
ajbspi-84390	160	4	]	]	PUNCT
ajbspi-84390	161	1	[	[	X
ajbspi-84390	161	2	crossref	crossref	X
ajbspi-84390	161	3	]	]	X
ajbspi-84390	161	4	bharti	bharti	PROPN
ajbspi-84390	161	5	,	,	PUNCT
ajbspi-84390	161	6	k.	k.	PROPN
ajbspi-84390	161	7	;	;	PUNCT
ajbspi-84390	161	8	den	den	PROPN
ajbspi-84390	161	9	hollander	hollander	PROPN
ajbspi-84390	161	10	,	,	PUNCT
ajbspi-84390	161	11	a.i	a.i	PROPN
ajbspi-84390	161	12	.	.	PROPN
ajbspi-84390	161	13	;	;	PUNCT
ajbspi-84390	161	14	lakkaraju	lakkaraju	PROPN
ajbspi-84390	161	15	,	,	PUNCT
ajbspi-84390	161	16	a.	a.	NOUN
ajbspi-84390	161	17	;	;	PUNCT
ajbspi-84390	161	18	sinha	sinha	NOUN
ajbspi-84390	161	19	,	,	PUNCT
ajbspi-84390	161	20	d.	d.	PROPN
ajbspi-84390	161	21	;	;	PUNCT
ajbspi-84390	161	22	williams	williams	PROPN
ajbspi-84390	161	23	,	,	PUNCT
ajbspi-84390	161	24	d.s	d.s	PROPN
ajbspi-84390	161	25	.	.	PROPN
ajbspi-84390	161	26	;	;	PUNCT
ajbspi-84390	161	27	finnemann	finnemann	PROPN
ajbspi-84390	161	28	,	,	PUNCT
ajbspi-84390	161	29	s.c	s.c	PROPN
ajbspi-84390	161	30	.	.	PROPN
ajbspi-84390	161	31	;	;	PUNCT
ajbspi-84390	161	32	bowes	bowe	NOUN
ajbspi-84390	161	33	-	-	PUNCT
ajbspi-84390	161	34	rickman	rickman	PROPN
ajbspi-84390	161	35	,	,	PUNCT
ajbspi-84390	161	36	c.	c.	PROPN
ajbspi-84390	161	37	;	;	PUNCT
ajbspi-84390	161	38	malek	malek	PROPN
ajbspi-84390	161	39	,	,	PUNCT
ajbspi-84390	161	40	g.	g.	PROPN
ajbspi-84390	161	41	;	;	PUNCT
ajbspi-84390	161	42	d’amore	d’amore	PROPN
ajbspi-84390	161	43	,	,	PUNCT
ajbspi-84390	161	44	p.a	p.a	PROPN
ajbspi-84390	161	45	.	.	PROPN
ajbspi-84390	161	46	cell	cell	NOUN
ajbspi-84390	161	47	culture	culture	NOUN
ajbspi-84390	161	48	models	model	NOUN
ajbspi-84390	161	49	to	to	PART
ajbspi-84390	161	50	study	study	VERB
ajbspi-84390	161	51	retinal	retinal	ADJ
ajbspi-84390	161	52	pigment	pigment	NOUN
ajbspi-84390	161	53	epithelium	epithelium	NOUN
ajbspi-84390	161	54	-	-	PUNCT
ajbspi-84390	161	55	related	relate	VERB
ajbspi-84390	161	56	pathogenesis	pathogenesis	NOUN
ajbspi-84390	161	57	in	in	ADP
ajbspi-84390	161	58	age	age	NOUN
ajbspi-84390	161	59	-	-	PUNCT
ajbspi-84390	161	60	related	relate	VERB
ajbspi-84390	161	61	macular	macular	ADJ
ajbspi-84390	161	62	degeneration	degeneration	NOUN
ajbspi-84390	161	63	.	.	PUNCT
ajbspi-84390	162	1	exp	exp	NOUN
ajbspi-84390	162	2	.	.	PUNCT
ajbspi-84390	162	3	eye	eye	NOUN
ajbspi-84390	162	4	res	re	NOUN
ajbspi-84390	162	5	.	.	PUNCT
ajbspi-84390	162	6	2022	2022	NUM
ajbspi-84390	162	7	,	,	PUNCT
ajbspi-84390	162	8	222	222	NUM
ajbspi-84390	162	9	,	,	PUNCT
ajbspi-84390	162	10	109170	109170	NUM
ajbspi-84390	162	11	.	.	PUNCT
ajbspi-84390	163	1	[	[	X
ajbspi-84390	163	2	google	google	NOUN
ajbspi-84390	163	3	scholar	scholar	NOUN
ajbspi-84390	163	4	]	]	PUNCT
ajbspi-84390	164	1	[	[	X
ajbspi-84390	164	2	crossref	crossref	X
ajbspi-84390	164	3	]	]	X
ajbspi-84390	164	4	american	american	ADJ
ajbspi-84390	164	5	journal	journal	PROPN
ajbspi-84390	164	6	of	of	ADP
ajbspi-84390	164	7	applied	apply	VERB
ajbspi-84390	164	8	science	science	NOUN
ajbspi-84390	164	9	and	and	CCONJ
ajbspi-84390	164	10	technology	technology	NOUN
ajbspi-84390	164	11	6	6	NUM
ajbspi-84390	164	12	https://theusajournals.com/index.php/ajast	https://theusajournals.com/index.php/ajast	NOUN
ajbspi-84390	164	13	american	american	PROPN
ajbspi-84390	164	14	journal	journal	PROPN
ajbspi-84390	164	15	of	of	ADP
ajbspi-84390	164	16	applied	apply	VERB
ajbspi-84390	164	17	science	science	NOUN
ajbspi-84390	164	18	and	and	CCONJ
ajbspi-84390	164	19	technology	technology	NOUN
ajbspi-84390	164	20	(	(	PUNCT
ajbspi-84390	164	21	issn	issn	PROPN
ajbspi-84390	164	22	:	:	PUNCT
ajbspi-84390	164	23	2771	2771	NUM
ajbspi-84390	164	24	-	-	SYM
ajbspi-84390	164	25	2745	2745	NUM
ajbspi-84390	164	26	)	)	PUNCT
ajbspi-84390	164	27	alge	alge	PROPN
ajbspi-84390	164	28	,	,	PUNCT
ajbspi-84390	164	29	c.s	c.s	PROPN
ajbspi-84390	164	30	.	.	PROPN
ajbspi-84390	164	31	;	;	PUNCT
ajbspi-84390	164	32	hauck	hauck	PROPN
ajbspi-84390	164	33	,	,	PUNCT
ajbspi-84390	164	34	s.m	s.m	PROPN
ajbspi-84390	164	35	.	.	PROPN
ajbspi-84390	164	36	;	;	PUNCT
ajbspi-84390	164	37	priglinger	priglinger	PROPN
ajbspi-84390	164	38	,	,	PUNCT
ajbspi-84390	164	39	s.g	s.g	PROPN
ajbspi-84390	164	40	.	.	PROPN
ajbspi-84390	164	41	;	;	PUNCT
ajbspi-84390	164	42	kampik	kampik	PROPN
ajbspi-84390	164	43	,	,	PUNCT
ajbspi-84390	164	44	a.	a.	NOUN
ajbspi-84390	164	45	;	;	PUNCT
ajbspi-84390	164	46	ueffing	ueffing	NOUN
ajbspi-84390	164	47	,	,	PUNCT
ajbspi-84390	164	48	m.	m.	NOUN
ajbspi-84390	164	49	differential	differential	ADJ
ajbspi-84390	164	50	protein	protein	NOUN
ajbspi-84390	164	51	profiling	profiling	NOUN
ajbspi-84390	164	52	of	of	ADP
ajbspi-84390	164	53	primary	primary	ADJ
ajbspi-84390	164	54	versus	versus	ADP
ajbspi-84390	164	55	immortalized	immortalized	ADJ
ajbspi-84390	164	56	human	human	ADJ
ajbspi-84390	164	57	rpe	rpe	PROPN
ajbspi-84390	164	58	cells	cell	NOUN
ajbspi-84390	164	59	identifies	identify	VERB
ajbspi-84390	164	60	expression	expression	NOUN
ajbspi-84390	164	61	patterns	pattern	NOUN
ajbspi-84390	164	62	associated	associate	VERB
ajbspi-84390	164	63	with	with	ADP
ajbspi-84390	164	64	cytoskeletal	cytoskeletal	ADJ
ajbspi-84390	164	65	remodeling	remodeling	NOUN
ajbspi-84390	164	66	and	and	CCONJ
ajbspi-84390	164	67	cell	cell	NOUN
ajbspi-84390	164	68	survival	survival	NOUN
ajbspi-84390	164	69	.	.	PUNCT
ajbspi-84390	165	1	j.	j.	PROPN
ajbspi-84390	165	2	proteome	proteome	PROPN
ajbspi-84390	165	3	res	re	NOUN
ajbspi-84390	165	4	.	.	PUNCT
ajbspi-84390	166	1	2006	2006	NUM
ajbspi-84390	166	2	,	,	PUNCT
ajbspi-84390	166	3	5	5	NUM
ajbspi-84390	166	4	,	,	PUNCT
ajbspi-84390	166	5	862–878	862–878	NUM
ajbspi-84390	166	6	.	.	PUNCT
ajbspi-84390	167	1	[	[	X
ajbspi-84390	167	2	google	google	NOUN
ajbspi-84390	167	3	scholar	scholar	NOUN
ajbspi-84390	167	4	]	]	PUNCT
ajbspi-84390	168	1	[	[	X
ajbspi-84390	168	2	crossref	crossref	X
ajbspi-84390	168	3	]	]	X
ajbspi-84390	168	4	dunn	dunn	PROPN
ajbspi-84390	168	5	,	,	PUNCT
ajbspi-84390	168	6	k.c	k.c	PROPN
ajbspi-84390	168	7	.	.	PROPN
ajbspi-84390	168	8	;	;	PUNCT
ajbspi-84390	168	9	aotaki	aotaki	NOUN
ajbspi-84390	168	10	-	-	PUNCT
ajbspi-84390	168	11	keen	keen	ADJ
ajbspi-84390	168	12	,	,	PUNCT
ajbspi-84390	168	13	a.e	a.e	PROPN
ajbspi-84390	168	14	.	.	PROPN
ajbspi-84390	168	15	;	;	PUNCT
ajbspi-84390	168	16	putkey	putkey	NOUN
ajbspi-84390	168	17	,	,	PUNCT
ajbspi-84390	168	18	f.r	f.r	PROPN
ajbspi-84390	168	19	.	.	NOUN
ajbspi-84390	168	20	;	;	PUNCT
ajbspi-84390	168	21	hjelmeland	hjelmeland	NOUN
ajbspi-84390	168	22	,	,	PUNCT
ajbspi-84390	168	23	l.m	l.m	PROPN
ajbspi-84390	168	24	.	.	PROPN
ajbspi-84390	168	25	arpe-19	arpe-19	PROPN
ajbspi-84390	168	26	,	,	PUNCT
ajbspi-84390	168	27	a	a	DET
ajbspi-84390	168	28	human	human	ADJ
ajbspi-84390	168	29	retinal	retinal	ADJ
ajbspi-84390	168	30	pigment	pigment	ADJ
ajbspi-84390	168	31	epithelial	epithelial	ADJ
ajbspi-84390	168	32	cell	cell	NOUN
ajbspi-84390	168	33	line	line	NOUN
ajbspi-84390	168	34	with	with	ADP
ajbspi-84390	168	35	differentiated	differentiated	ADJ
ajbspi-84390	168	36	properties	property	NOUN
ajbspi-84390	168	37	.	.	PUNCT
ajbspi-84390	169	1	exp	exp	NOUN
ajbspi-84390	169	2	.	.	PUNCT
ajbspi-84390	169	3	eye	eye	NOUN
ajbspi-84390	169	4	res	re	NOUN
ajbspi-84390	169	5	.	.	PUNCT
ajbspi-84390	169	6	1996	1996	NUM
ajbspi-84390	169	7	,	,	PUNCT
ajbspi-84390	169	8	62	62	NUM
ajbspi-84390	169	9	,	,	PUNCT
ajbspi-84390	169	10	155–169	155–169	NUM
ajbspi-84390	169	11	.	.	PUNCT
ajbspi-84390	170	1	[	[	X
ajbspi-84390	170	2	google	google	NOUN
ajbspi-84390	170	3	scholar	scholar	NOUN
ajbspi-84390	170	4	]	]	PUNCT
ajbspi-84390	171	1	[	[	X
ajbspi-84390	171	2	crossref	crossref	X
ajbspi-84390	171	3	]	]	X
ajbspi-84390	171	4	tian	tian	PROPN
ajbspi-84390	171	5	,	,	PUNCT
ajbspi-84390	171	6	j.	j.	PROPN
ajbspi-84390	171	7	;	;	PUNCT
ajbspi-84390	171	8	ishibashi	ishibashi	PROPN
ajbspi-84390	171	9	,	,	PUNCT
ajbspi-84390	171	10	k.	k.	PROPN
ajbspi-84390	171	11	;	;	PUNCT
ajbspi-84390	171	12	honda	honda	PROPN
ajbspi-84390	171	13	,	,	PUNCT
ajbspi-84390	171	14	s.	s.	PROPN
ajbspi-84390	171	15	;	;	PUNCT
ajbspi-84390	171	16	boylan	boylan	PROPN
ajbspi-84390	171	17	,	,	PUNCT
ajbspi-84390	171	18	s.a	s.a	PROPN
ajbspi-84390	171	19	.	.	PROPN
ajbspi-84390	171	20	;	;	PUNCT
ajbspi-84390	171	21	hjelmeland	hjelmeland	NOUN
ajbspi-84390	171	22	,	,	PUNCT
ajbspi-84390	171	23	l.m	l.m	PROPN
ajbspi-84390	171	24	.	.	PROPN
ajbspi-84390	171	25	;	;	PUNCT
ajbspi-84390	171	26	handa	handa	PROPN
ajbspi-84390	171	27	,	,	PUNCT
ajbspi-84390	171	28	j.t	j.t	PROPN
ajbspi-84390	171	29	.	.	PROPN
ajbspi-84390	172	1	the	the	DET
ajbspi-84390	172	2	expression	expression	NOUN
ajbspi-84390	172	3	of	of	ADP
ajbspi-84390	172	4	native	native	ADJ
ajbspi-84390	172	5	and	and	CCONJ
ajbspi-84390	172	6	cultured	cultured	ADJ
ajbspi-84390	172	7	human	human	ADJ
ajbspi-84390	172	8	retinal	retinal	ADJ
ajbspi-84390	172	9	pigment	pigment	ADJ
ajbspi-84390	172	10	epithelial	epithelial	ADJ
ajbspi-84390	172	11	cells	cell	NOUN
ajbspi-84390	172	12	grown	grow	VERB
ajbspi-84390	172	13	in	in	ADP
ajbspi-84390	172	14	different	different	ADJ
ajbspi-84390	172	15	culture	culture	NOUN
ajbspi-84390	172	16	conditions	condition	NOUN
ajbspi-84390	172	17	.	.	PUNCT
ajbspi-84390	173	1	br	br	X
ajbspi-84390	173	2	.	.	PUNCT
ajbspi-84390	174	1	j.	j.	PROPN
ajbspi-84390	174	2	ophthalmol	ophthalmol	PROPN
ajbspi-84390	174	3	.	.	PUNCT
ajbspi-84390	175	1	2005	2005	NUM
ajbspi-84390	175	2	,	,	PUNCT
ajbspi-84390	175	3	89	89	NUM
ajbspi-84390	175	4	,	,	PUNCT
ajbspi-84390	175	5	1510–1517	1510–1517	NUM
ajbspi-84390	175	6	.	.	PUNCT
ajbspi-84390	176	1	[	[	X
ajbspi-84390	176	2	google	google	NOUN
ajbspi-84390	176	3	scholar	scholar	NOUN
ajbspi-84390	176	4	]	]	PUNCT
ajbspi-84390	177	1	[	[	X
ajbspi-84390	177	2	crossref	crossref	X
ajbspi-84390	177	3	]	]	X
ajbspi-84390	177	4	[	[	X
ajbspi-84390	177	5	pubmed	pubmed	X
ajbspi-84390	177	6	]	]	X
ajbspi-84390	177	7	ahmado	ahmado	PROPN
ajbspi-84390	177	8	,	,	PUNCT
ajbspi-84390	177	9	a.	a.	NOUN
ajbspi-84390	177	10	;	;	PUNCT
ajbspi-84390	177	11	carr	carr	PROPN
ajbspi-84390	177	12	,	,	PUNCT
ajbspi-84390	177	13	a.-j	a.-j	PROPN
ajbspi-84390	177	14	.	.	PUNCT
ajbspi-84390	177	15	;	;	PUNCT
ajbspi-84390	177	16	vugler	vugler	NOUN
ajbspi-84390	177	17	,	,	PUNCT
ajbspi-84390	177	18	a.a	a.a	PROPN
ajbspi-84390	177	19	.	.	PROPN
ajbspi-84390	177	20	;	;	PUNCT
ajbspi-84390	178	1	gias	gias	PROPN
ajbspi-84390	178	2	,	,	PUNCT
ajbspi-84390	178	3	c.	c.	PROPN
ajbspi-84390	178	4	;	;	PUNCT
ajbspi-84390	178	5	lawrence	lawrence	PROPN
ajbspi-84390	178	6	,	,	PUNCT
ajbspi-84390	178	7	j.m	j.m	PROPN
ajbspi-84390	178	8	.	.	PROPN
ajbspi-84390	178	9	;	;	PUNCT
ajbspi-84390	178	10	chen	chen	PROPN
ajbspi-84390	178	11	,	,	PUNCT
ajbspi-84390	178	12	l.l	l.l	PROPN
ajbspi-84390	178	13	.	.	PROPN
ajbspi-84390	178	14	;	;	PUNCT
ajbspi-84390	178	15	chen	chen	PROPN
ajbspi-84390	178	16	,	,	PUNCT
ajbspi-84390	178	17	f.k	f.k	PROPN
ajbspi-84390	178	18	.	.	PROPN
ajbspi-84390	178	19	;	;	PUNCT
ajbspi-84390	178	20	turowski	turowski	PROPN
ajbspi-84390	178	21	,	,	PUNCT
ajbspi-84390	178	22	p.	p.	NOUN
ajbspi-84390	178	23	;	;	PUNCT
ajbspi-84390	178	24	da	da	PROPN
ajbspi-84390	178	25	cruz	cruz	PROPN
ajbspi-84390	178	26	,	,	PUNCT
ajbspi-84390	178	27	l.	l.	PROPN
ajbspi-84390	178	28	;	;	PUNCT
ajbspi-84390	178	29	coffey	coffey	PROPN
ajbspi-84390	178	30	,	,	PUNCT
ajbspi-84390	178	31	p.j	p.j	PROPN
ajbspi-84390	178	32	.	.	PROPN
ajbspi-84390	178	33	induction	induction	NOUN
ajbspi-84390	178	34	of	of	ADP
ajbspi-84390	178	35	differentiation	differentiation	NOUN
ajbspi-84390	178	36	by	by	ADP
ajbspi-84390	178	37	pyruvate	pyruvate	NOUN
ajbspi-84390	178	38	and	and	CCONJ
ajbspi-84390	178	39	dmem	dmem	VERB
ajbspi-84390	178	40	in	in	ADP
ajbspi-84390	178	41	the	the	DET
ajbspi-84390	178	42	human	human	ADJ
ajbspi-84390	178	43	retinal	retinal	ADJ
ajbspi-84390	178	44	pigment	pigment	NOUN
ajbspi-84390	178	45	epithelium	epithelium	NOUN
ajbspi-84390	178	46	cell	cell	NOUN
ajbspi-84390	178	47	line	line	NOUN
ajbspi-84390	178	48	arpe-19	arpe-19	PROPN
ajbspi-84390	178	49	.	.	PUNCT
ajbspi-84390	178	50	investig	investig	PROPN
ajbspi-84390	178	51	.	.	PUNCT
ajbspi-84390	178	52	ophthalmol	ophthalmol	PROPN
ajbspi-84390	178	53	.	.	PUNCT
ajbspi-84390	179	1	vis	vis	X
ajbspi-84390	179	2	.	.	PUNCT
ajbspi-84390	180	1	sci	sci	PROPN
ajbspi-84390	180	2	.	.	PROPN
ajbspi-84390	180	3	2011	2011	NUM
ajbspi-84390	180	4	,	,	PUNCT
ajbspi-84390	180	5	52	52	NUM
ajbspi-84390	180	6	,	,	PUNCT
ajbspi-84390	180	7	7148–7159	7148–7159	NUM
ajbspi-84390	180	8	.	.	PUNCT
ajbspi-84390	181	1	[	[	X
ajbspi-84390	181	2	google	google	NOUN
ajbspi-84390	181	3	scholar	scholar	NOUN
ajbspi-84390	181	4	]	]	PUNCT
ajbspi-84390	182	1	[	[	X
ajbspi-84390	182	2	crossref	crossref	X
ajbspi-84390	182	3	]	]	X
ajbspi-84390	182	4	[	[	X
ajbspi-84390	182	5	pubmed	pubmed	X
ajbspi-84390	182	6	]	]	X
ajbspi-84390	182	7	samuel	samuel	PROPN
ajbspi-84390	182	8	,	,	PUNCT
ajbspi-84390	182	9	w.	w.	PROPN
ajbspi-84390	182	10	;	;	PUNCT
ajbspi-84390	182	11	jaworski	jaworski	PROPN
ajbspi-84390	182	12	,	,	PUNCT
ajbspi-84390	182	13	c.	c.	PROPN
ajbspi-84390	182	14	;	;	PUNCT
ajbspi-84390	182	15	postnikova	postnikova	PROPN
ajbspi-84390	182	16	,	,	PUNCT
ajbspi-84390	182	17	o.a	o.a	PROPN
ajbspi-84390	182	18	.	.	PROPN
ajbspi-84390	182	19	;	;	PUNCT
ajbspi-84390	182	20	kutty	kutty	PROPN
ajbspi-84390	182	21	,	,	PUNCT
ajbspi-84390	182	22	r.k	r.k	PROPN
ajbspi-84390	182	23	.	.	PROPN
ajbspi-84390	182	24	;	;	PUNCT
ajbspi-84390	182	25	duncan	duncan	PROPN
ajbspi-84390	182	26	,	,	PUNCT
ajbspi-84390	182	27	t.	t.	PROPN
ajbspi-84390	182	28	;	;	PUNCT
ajbspi-84390	182	29	tan	tan	PROPN
ajbspi-84390	182	30	,	,	PUNCT
ajbspi-84390	182	31	l.x	l.x	PROPN
ajbspi-84390	182	32	.	.	PROPN
ajbspi-84390	182	33	;	;	PUNCT
ajbspi-84390	182	34	poliakov	poliakov	PROPN
ajbspi-84390	182	35	,	,	PUNCT
ajbspi-84390	182	36	e.	e.	PROPN
ajbspi-84390	182	37	;	;	PUNCT
ajbspi-84390	182	38	lakkaraju	lakkaraju	PROPN
ajbspi-84390	182	39	,	,	PUNCT
ajbspi-84390	182	40	a.	a.	NOUN
ajbspi-84390	182	41	;	;	PUNCT
ajbspi-84390	182	42	redmond	redmond	PROPN
ajbspi-84390	182	43	,	,	PUNCT
ajbspi-84390	182	44	t.m	t.m	PROPN
ajbspi-84390	182	45	.	.	PROPN
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ajbspi-84390	182	47	differentiated	differentiate	VERB
ajbspi-84390	182	48	arpe-19	arpe-19	PROPN
ajbspi-84390	182	49	cells	cell	NOUN
ajbspi-84390	182	50	regain	regain	VERB
ajbspi-84390	182	51	phenotype	phenotype	NOUN
ajbspi-84390	182	52	and	and	CCONJ
ajbspi-84390	182	53	gene	gene	NOUN
ajbspi-84390	182	54	expression	expression	NOUN
ajbspi-84390	182	55	profiles	profile	NOUN
ajbspi-84390	182	56	similar	similar	ADJ
ajbspi-84390	182	57	to	to	ADP
ajbspi-84390	182	58	those	those	PRON
ajbspi-84390	182	59	of	of	ADP
ajbspi-84390	182	60	native	native	ADJ
ajbspi-84390	182	61	rpe	rpe	PROPN
ajbspi-84390	182	62	cells	cell	NOUN
ajbspi-84390	182	63	.	.	PUNCT
ajbspi-84390	183	1	mol	mol	PROPN
ajbspi-84390	183	2	.	.	PUNCT
ajbspi-84390	184	1	vis	vis	X
ajbspi-84390	184	2	.	.	PROPN
ajbspi-84390	184	3	2017	2017	NUM
ajbspi-84390	184	4	,	,	PUNCT
ajbspi-84390	184	5	23	23	NUM
ajbspi-84390	184	6	,	,	PUNCT
ajbspi-84390	184	7	60–89	60–89	NUM
ajbspi-84390	184	8	.	.	PUNCT
ajbspi-84390	185	1	[	[	X
ajbspi-84390	185	2	google	google	NOUN
ajbspi-84390	185	3	scholar	scholar	NOUN
ajbspi-84390	185	4	]	]	PUNCT
ajbspi-84390	186	1	[	[	X
ajbspi-84390	186	2	pubmed	pubmed	X
ajbspi-84390	186	3	]	]	PUNCT
ajbspi-84390	186	4	golconda	golconda	NOUN
ajbspi-84390	186	5	,	,	PUNCT
ajbspi-84390	186	6	p.	p.	NOUN
ajbspi-84390	186	7	;	;	PUNCT
ajbspi-84390	186	8	andrade	andrade	PROPN
ajbspi-84390	186	9	-	-	PUNCT
ajbspi-84390	186	10	medina	medina	PROPN
ajbspi-84390	186	11	,	,	PUNCT
ajbspi-84390	186	12	m.	m.	NOUN
ajbspi-84390	186	13	;	;	PUNCT
ajbspi-84390	186	14	oberstein	oberstein	NOUN
ajbspi-84390	186	15	,	,	PUNCT
ajbspi-84390	186	16	a.	a.	NOUN
ajbspi-84390	186	17	subconfluent	subconfluent	NOUN
ajbspi-84390	186	18	arpe-19	arpe-19	PROPN
ajbspi-84390	186	19	cells	cell	NOUN
ajbspi-84390	186	20	display	display	VERB
ajbspi-84390	186	21	mesenchymal	mesenchymal	NOUN
ajbspi-84390	186	22	cellstate	cellstate	NOUN
ajbspi-84390	186	23	characteristics	characteristic	NOUN
ajbspi-84390	186	24	and	and	CCONJ
ajbspi-84390	186	25	behave	behave	VERB
ajbspi-84390	186	26	like	like	ADP
ajbspi-84390	186	27	fibroblasts	fibroblast	NOUN
ajbspi-84390	186	28	,	,	PUNCT
ajbspi-84390	186	29	rather	rather	ADV
ajbspi-84390	186	30	than	than	ADP
ajbspi-84390	186	31	epithelial	epithelial	ADJ
ajbspi-84390	186	32	cells	cell	NOUN
ajbspi-84390	186	33	,	,	PUNCT
ajbspi-84390	186	34	in	in	ADP
ajbspi-84390	186	35	experimental	experimental	ADJ
ajbspi-84390	186	36	hcmv	hcmv	ADJ
ajbspi-84390	186	37	infection	infection	NOUN
ajbspi-84390	186	38	studies	study	NOUN
ajbspi-84390	186	39	.	.	PUNCT
ajbspi-84390	187	1	viruses	virus	NOUN
ajbspi-84390	187	2	2023	2023	NUM
ajbspi-84390	187	3	,	,	PUNCT
ajbspi-84390	187	4	16	16	NUM
ajbspi-84390	187	5	,	,	PUNCT
ajbspi-84390	187	6	49	49	NUM
ajbspi-84390	187	7	.	.	PUNCT
ajbspi-84390	188	1	[	[	X
ajbspi-84390	188	2	google	google	NOUN
ajbspi-84390	188	3	scholar	scholar	NOUN
ajbspi-84390	188	4	]	]	PUNCT
ajbspi-84390	189	1	[	[	X
ajbspi-84390	189	2	crossref	crossref	X
ajbspi-84390	189	3	]	]	X
ajbspi-84390	189	4	luo	luo	PROPN
ajbspi-84390	189	5	,	,	PUNCT
ajbspi-84390	189	6	y.	y.	PROPN
ajbspi-84390	189	7	;	;	PUNCT
ajbspi-84390	189	8	zhuo	zhuo	PROPN
ajbspi-84390	189	9	,	,	PUNCT
ajbspi-84390	189	10	y.	y.	PROPN
ajbspi-84390	189	11	;	;	PUNCT
ajbspi-84390	189	12	fukuhara	fukuhara	NOUN
ajbspi-84390	189	13	,	,	PUNCT
ajbspi-84390	189	14	m.	m.	NOUN
ajbspi-84390	189	15	;	;	PUNCT
ajbspi-84390	189	16	rizzolo	rizzolo	NOUN
ajbspi-84390	189	17	,	,	PUNCT
ajbspi-84390	189	18	l.j	l.j	PROPN
ajbspi-84390	189	19	.	.	PROPN
ajbspi-84390	189	20	effects	effect	NOUN
ajbspi-84390	189	21	of	of	ADP
ajbspi-84390	189	22	culture	culture	NOUN
ajbspi-84390	189	23	conditions	condition	NOUN
ajbspi-84390	189	24	on	on	ADP
ajbspi-84390	189	25	heterogeneity	heterogeneity	NOUN
ajbspi-84390	189	26	and	and	CCONJ
ajbspi-84390	189	27	the	the	DET
ajbspi-84390	189	28	apical	apical	ADJ
ajbspi-84390	189	29	junctional	junctional	ADJ
ajbspi-84390	189	30	complex	complex	NOUN
ajbspi-84390	189	31	of	of	ADP
ajbspi-84390	189	32	the	the	DET
ajbspi-84390	189	33	arpe-19	arpe-19	PROPN
ajbspi-84390	189	34	cell	cell	NOUN
ajbspi-84390	189	35	line	line	NOUN
ajbspi-84390	189	36	.	.	PUNCT
ajbspi-84390	190	1	investig	investig	PROPN
ajbspi-84390	190	2	.	.	PUNCT
ajbspi-84390	190	3	ophthalmol	ophthalmol	PROPN
ajbspi-84390	190	4	.	.	PUNCT
ajbspi-84390	191	1	vis	vis	X
ajbspi-84390	191	2	.	.	PUNCT
ajbspi-84390	192	1	sci	sci	PROPN
ajbspi-84390	192	2	.	.	PROPN
ajbspi-84390	192	3	2006	2006	NUM
ajbspi-84390	192	4	,	,	PUNCT
ajbspi-84390	192	5	47	47	NUM
ajbspi-84390	192	6	,	,	PUNCT
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ajbspi-84390	192	8	.	.	PUNCT
ajbspi-84390	193	1	[	[	X
ajbspi-84390	193	2	google	google	NOUN
ajbspi-84390	193	3	scholar	scholar	NOUN
ajbspi-84390	193	4	]	]	PUNCT
ajbspi-84390	194	1	[	[	X
ajbspi-84390	194	2	crossref	crossref	X
ajbspi-84390	194	3	]	]	X
ajbspi-84390	194	4	nakai	nakai	PROPN
ajbspi-84390	194	5	-	-	PUNCT
ajbspi-84390	194	6	futatsugi	futatsugi	NOUN
ajbspi-84390	194	7	,	,	PUNCT
ajbspi-84390	194	8	y.	y.	PROPN
ajbspi-84390	194	9	;	;	PUNCT
ajbspi-84390	194	10	jin	jin	PROPN
ajbspi-84390	194	11	,	,	PUNCT
ajbspi-84390	194	12	j.	j.	PROPN
ajbspi-84390	194	13	;	;	PUNCT
ajbspi-84390	194	14	ogawa	ogawa	PROPN
ajbspi-84390	194	15	,	,	PUNCT
ajbspi-84390	194	16	t.	t.	PROPN
ajbspi-84390	194	17	;	;	PUNCT
ajbspi-84390	194	18	sakai	sakai	PROPN
ajbspi-84390	194	19	,	,	PUNCT
ajbspi-84390	194	20	n.	n.	NOUN
ajbspi-84390	194	21	;	;	PUNCT
ajbspi-84390	194	22	maeda	maeda	PROPN
ajbspi-84390	194	23	,	,	PUNCT
ajbspi-84390	194	24	a.	a.	PROPN
ajbspi-84390	194	25	;	;	PUNCT
ajbspi-84390	194	26	hironaka	hironaka	PROPN
ajbspi-84390	194	27	,	,	PUNCT
ajbspi-84390	194	28	k.-i	k.-i	PROPN
ajbspi-84390	194	29	.	.	PROPN
ajbspi-84390	194	30	;	;	PUNCT
ajbspi-84390	194	31	fukuda	fukuda	PROPN
ajbspi-84390	194	32	,	,	PUNCT
ajbspi-84390	194	33	m.	m.	NOUN
ajbspi-84390	194	34	;	;	PUNCT
ajbspi-84390	194	35	danno	danno	PROPN
ajbspi-84390	194	36	,	,	PUNCT
ajbspi-84390	194	37	h.	h.	PROPN
ajbspi-84390	194	38	;	;	PUNCT
ajbspi-84390	194	39	tanaka	tanaka	PROPN
ajbspi-84390	194	40	,	,	PUNCT
ajbspi-84390	194	41	y.	y.	PROPN
ajbspi-84390	194	42	;	;	PUNCT
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ajbspi-84390	194	44	,	,	PUNCT
ajbspi-84390	194	45	s.	s.	PROPN
ajbspi-84390	194	46	;	;	PUNCT
ajbspi-84390	194	47	et	et	PROPN
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ajbspi-84390	194	49	.	.	PROPN
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ajbspi-84390	194	51	level	level	NOUN
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ajbspi-84390	194	53	human	human	ADJ
ajbspi-84390	194	54	ipscderived	ipscderive	VERB
ajbspi-84390	194	55	rpe	rpe	PROPN
ajbspi-84390	194	56	does	do	AUX
ajbspi-84390	194	57	not	not	PART
ajbspi-84390	194	58	indicate	indicate	VERB
ajbspi-84390	194	59	a	a	DET
ajbspi-84390	194	60	specific	specific	ADJ
ajbspi-84390	194	61	gene	gene	NOUN
ajbspi-84390	194	62	expression	expression	NOUN
ajbspi-84390	194	63	profile	profile	NOUN
ajbspi-84390	194	64	.	.	PUNCT
ajbspi-84390	195	1	elife	elife	NOUN
ajbspi-84390	195	2	2024	2024	NUM
ajbspi-84390	195	3	,	,	PUNCT
ajbspi-84390	195	4	12	12	NUM
ajbspi-84390	195	5	,	,	PUNCT
ajbspi-84390	195	6	rp92510	rp92510	ADJ
ajbspi-84390	195	7	.	.	PUNCT
ajbspi-84390	196	1	[	[	X
ajbspi-84390	196	2	google	google	NOUN
ajbspi-84390	196	3	scholar	scholar	NOUN
ajbspi-84390	196	4	]	]	PUNCT
ajbspi-84390	197	1	[	[	X
ajbspi-84390	197	2	crossref	crossref	X
ajbspi-84390	197	3	]	]	X
ajbspi-84390	197	4	farjood	farjood	PROPN
ajbspi-84390	197	5	,	,	PUNCT
ajbspi-84390	197	6	f.	f.	PROPN
ajbspi-84390	197	7	;	;	PUNCT
ajbspi-84390	197	8	manos	manos	PROPN
ajbspi-84390	197	9	,	,	PUNCT
ajbspi-84390	197	10	j.d	j.d	PROPN
ajbspi-84390	197	11	.	.	PROPN
ajbspi-84390	197	12	;	;	PUNCT
ajbspi-84390	197	13	wang	wang	PROPN
ajbspi-84390	197	14	,	,	PUNCT
ajbspi-84390	197	15	y.	y.	PROPN
ajbspi-84390	197	16	;	;	PUNCT
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ajbspi-84390	197	18	,	,	PUNCT
ajbspi-84390	197	19	a.l	a.l	PROPN
ajbspi-84390	197	20	.	.	PROPN
ajbspi-84390	197	21	;	;	PUNCT
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ajbspi-84390	197	23	,	,	PUNCT
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ajbspi-84390	197	25	;	;	PUNCT
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ajbspi-84390	197	27	,	,	PUNCT
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ajbspi-84390	197	29	;	;	PUNCT
ajbspi-84390	197	30	alam	alam	PROPN
ajbspi-84390	197	31	,	,	PUNCT
ajbspi-84390	197	32	n.	n.	NOUN
ajbspi-84390	197	33	;	;	PUNCT
ajbspi-84390	197	34	prusky	prusky	ADJ
ajbspi-84390	197	35	,	,	PUNCT
ajbspi-84390	197	36	g.	g.	PROPN
ajbspi-84390	197	37	;	;	PUNCT
ajbspi-84390	197	38	temple	temple	PROPN
ajbspi-84390	197	39	,	,	PUNCT
ajbspi-84390	197	40	s.	s.	PROPN
ajbspi-84390	197	41	;	;	PUNCT
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ajbspi-84390	197	43	,	,	PUNCT
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ajbspi-84390	197	45	.	.	PROPN
ajbspi-84390	197	46	;	;	PUNCT
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ajbspi-84390	197	52	of	of	ADP
ajbspi-84390	197	53	heterogeneity	heterogeneity	NOUN
ajbspi-84390	197	54	and	and	CCONJ
ajbspi-84390	197	55	transplantation	transplantation	NOUN
ajbspi-84390	197	56	efficacy	efficacy	NOUN
ajbspi-84390	197	57	in	in	ADP
ajbspi-84390	197	58	retinal	retinal	ADJ
ajbspi-84390	197	59	pigment	pigment	ADJ
ajbspi-84390	197	60	epithelial	epithelial	ADJ
ajbspi-84390	197	61	cells	cell	NOUN
ajbspi-84390	197	62	.	.	PUNCT
ajbspi-84390	198	1	j.	j.	PROPN
ajbspi-84390	198	2	exp	exp	PROPN
ajbspi-84390	198	3	.	.	PROPN
ajbspi-84390	198	4	med	med	PROPN
ajbspi-84390	198	5	.	.	PROPN
ajbspi-84390	198	6	2023	2023	NUM
ajbspi-84390	198	7	,	,	PUNCT
ajbspi-84390	198	8	220	220	NUM
ajbspi-84390	198	9	,	,	PUNCT
ajbspi-84390	198	10	e20230913	e20230913	PROPN
ajbspi-84390	198	11	.	.	PUNCT
ajbspi-84390	199	1	[	[	X
ajbspi-84390	199	2	google	google	NOUN
ajbspi-84390	199	3	scholar	scholar	NOUN
ajbspi-84390	199	4	]	]	PUNCT
ajbspi-84390	200	1	[	[	X
ajbspi-84390	200	2	crossref	crossref	X
ajbspi-84390	200	3	]	]	X
ajbspi-84390	200	4	miyagishima	miyagishima	PROPN
ajbspi-84390	200	5	,	,	PUNCT
ajbspi-84390	200	6	k.j	k.j	PROPN
ajbspi-84390	200	7	.	.	PROPN
ajbspi-84390	200	8	;	;	PUNCT
ajbspi-84390	200	9	wan	wan	PROPN
ajbspi-84390	200	10	,	,	PUNCT
ajbspi-84390	200	11	q.	q.	PROPN
ajbspi-84390	200	12	;	;	PUNCT
ajbspi-84390	200	13	corneo	corneo	PROPN
ajbspi-84390	200	14	,	,	PUNCT
ajbspi-84390	200	15	b.	b.	PROPN
ajbspi-84390	200	16	;	;	PUNCT
ajbspi-84390	200	17	sharma	sharma	PROPN
ajbspi-84390	200	18	,	,	PUNCT
ajbspi-84390	200	19	r.	r.	PROPN
ajbspi-84390	200	20	;	;	PUNCT
ajbspi-84390	200	21	lotfi	lotfi	PROPN
ajbspi-84390	200	22	,	,	PUNCT
ajbspi-84390	200	23	m.r	m.r	PROPN
ajbspi-84390	200	24	.	.	PROPN
ajbspi-84390	200	25	;	;	PUNCT
ajbspi-84390	200	26	boles	boles	PROPN
ajbspi-84390	200	27	,	,	PUNCT
ajbspi-84390	200	28	n.c	n.c	PROPN
ajbspi-84390	200	29	.	.	PROPN
ajbspi-84390	200	30	;	;	PUNCT
ajbspi-84390	200	31	hua	hua	PROPN
ajbspi-84390	200	32	,	,	PUNCT
ajbspi-84390	200	33	f.	f.	PROPN
ajbspi-84390	200	34	;	;	PUNCT
ajbspi-84390	200	35	maminishkis	maminishki	NOUN
ajbspi-84390	200	36	,	,	PUNCT
ajbspi-84390	200	37	a.	a.	NOUN
ajbspi-84390	200	38	;	;	PUNCT
ajbspi-84390	200	39	zhang	zhang	PROPN
ajbspi-84390	200	40	,	,	PUNCT
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ajbspi-84390	200	42	;	;	PUNCT
ajbspi-84390	200	43	blenkinsop	blenkinsop	NOUN
ajbspi-84390	200	44	,	,	PUNCT
ajbspi-84390	200	45	t.	t.	PROPN
ajbspi-84390	200	46	;	;	PUNCT
ajbspi-84390	200	47	et	et	PROPN
ajbspi-84390	200	48	al	al	PROPN
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ajbspi-84390	201	5	:	:	PUNCT
ajbspi-84390	201	6	induced	induce	VERB
ajbspi-84390	201	7	pluripotent	pluripotent	ADJ
ajbspi-84390	201	8	stem	stem	NOUN
ajbspi-84390	201	9	cell	cell	NOUN
ajbspi-84390	201	10	-	-	PUNCT
ajbspi-84390	201	11	derived	derive	VERB
ajbspi-84390	201	12	retinal	retinal	ADJ
ajbspi-84390	201	13	pigment	pigment	NOUN
ajbspi-84390	201	14	epithelium	epithelium	NOUN
ajbspi-84390	201	15	for	for	ADP
ajbspi-84390	201	16	clinical	clinical	ADJ
ajbspi-84390	201	17	applications	application	NOUN
ajbspi-84390	201	18	.	.	PUNCT
ajbspi-84390	202	1	stem	stem	NOUN
ajbspi-84390	202	2	cells	cell	NOUN
ajbspi-84390	202	3	transl	transl	PROPN
ajbspi-84390	202	4	.	.	PUNCT
ajbspi-84390	203	1	med	med	PROPN
ajbspi-84390	203	2	.	.	PROPN
ajbspi-84390	203	3	2016	2016	NUM
ajbspi-84390	203	4	,	,	PUNCT
ajbspi-84390	203	5	5	5	NUM
ajbspi-84390	203	6	,	,	PUNCT
ajbspi-84390	203	7	1562–1574	1562–1574	NUM
ajbspi-84390	203	8	.	.	PUNCT
ajbspi-84390	204	1	[	[	X
ajbspi-84390	204	2	google	google	NOUN
ajbspi-84390	204	3	scholar	scholar	NOUN
ajbspi-84390	204	4	]	]	PUNCT
ajbspi-84390	205	1	[	[	X
ajbspi-84390	205	2	crossref	crossref	X
ajbspi-84390	205	3	]	]	X
ajbspi-84390	205	4	rzhanova	rzhanova	PROPN
ajbspi-84390	205	5	,	,	PUNCT
ajbspi-84390	205	6	l.a	l.a	PROPN
ajbspi-84390	205	7	.	.	PROPN
ajbspi-84390	205	8	;	;	PUNCT
ajbspi-84390	205	9	markitantova	markitantova	X
ajbspi-84390	205	10	,	,	PUNCT
ajbspi-84390	205	11	y.v	y.v	PROPN
ajbspi-84390	205	12	.	.	PROPN
ajbspi-84390	205	13	;	;	PUNCT
ajbspi-84390	205	14	aleksandrova	aleksandrova	PROPN
ajbspi-84390	205	15	,	,	PUNCT
ajbspi-84390	205	16	m.a	m.a	PROPN
ajbspi-84390	205	17	.	.	PROPN
ajbspi-84390	205	18	recent	recent	ADJ
ajbspi-84390	205	19	achievements	achievement	NOUN
ajbspi-84390	205	20	in	in	ADP
ajbspi-84390	205	21	the	the	DET
ajbspi-84390	205	22	heterogeneity	heterogeneity	NOUN
ajbspi-84390	205	23	of	of	ADP
ajbspi-84390	205	24	mammalian	mammalian	ADJ
ajbspi-84390	205	25	and	and	CCONJ
ajbspi-84390	205	26	human	human	ADJ
ajbspi-84390	205	27	retinal	retinal	ADJ
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ajbspi-84390	205	29	epithelium	epithelium	NOUN
ajbspi-84390	205	30	:	:	PUNCT
ajbspi-84390	205	31	in	in	ADP
ajbspi-84390	205	32	search	search	NOUN
ajbspi-84390	205	33	of	of	ADP
ajbspi-84390	205	34	a	a	DET
ajbspi-84390	205	35	stem	stem	NOUN
ajbspi-84390	205	36	cell	cell	NOUN
ajbspi-84390	205	37	.	.	PUNCT
ajbspi-84390	206	1	cells	cell	NOUN
ajbspi-84390	206	2	2024	2024	NUM
ajbspi-84390	206	3	,	,	PUNCT
ajbspi-84390	206	4	13	13	NUM
ajbspi-84390	206	5	,	,	PUNCT
ajbspi-84390	206	6	281	281	NUM
ajbspi-84390	206	7	.	.	PUNCT
ajbspi-84390	207	1	[	[	X
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ajbspi-84390	207	3	scholar	scholar	NOUN
ajbspi-84390	207	4	]	]	PUNCT
ajbspi-84390	208	1	[	[	X
ajbspi-84390	208	2	crossref	crossref	X
ajbspi-84390	208	3	]	]	X
ajbspi-84390	208	4	luo	luo	PROPN
ajbspi-84390	208	5	,	,	PUNCT
ajbspi-84390	208	6	m.	m.	NOUN
ajbspi-84390	208	7	;	;	PUNCT
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ajbspi-84390	208	9	,	,	PUNCT
ajbspi-84390	208	10	y.	y.	PROPN
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ajbspi-84390	208	12	of	of	ADP
ajbspi-84390	208	13	stem	stem	NOUN
ajbspi-84390	208	14	cell	cell	NOUN
ajbspi-84390	208	15	-	-	PUNCT
ajbspi-84390	208	16	derived	derive	VERB
ajbspi-84390	208	17	retinal	retinal	ADJ
ajbspi-84390	208	18	pigmented	pigment	VERB
ajbspi-84390	208	19	epithelium	epithelium	NOUN
ajbspi-84390	208	20	in	in	ADP
ajbspi-84390	208	21	retinal	retinal	ADJ
ajbspi-84390	208	22	degenerative	degenerative	ADJ
ajbspi-84390	208	23	diseases	disease	NOUN
ajbspi-84390	208	24	:	:	PUNCT
ajbspi-84390	208	25	present	present	ADJ
ajbspi-84390	208	26	and	and	CCONJ
ajbspi-84390	208	27	future	future	ADJ
ajbspi-84390	208	28	.	.	PUNCT
ajbspi-84390	209	1	int	int	NOUN
ajbspi-84390	209	2	.	.	PUNCT
ajbspi-84390	210	1	j.	j.	PROPN
ajbspi-84390	210	2	ophthalmol	ophthalmol	PROPN
ajbspi-84390	210	3	.	.	PROPN
ajbspi-84390	211	1	2018	2018	NUM
ajbspi-84390	211	2	,	,	PUNCT
ajbspi-84390	211	3	11	11	NUM
ajbspi-84390	211	4	,	,	PUNCT
ajbspi-84390	211	5	150–159	150–159	NUM
ajbspi-84390	211	6	.	.	PUNCT
ajbspi-84390	212	1	[	[	X
ajbspi-84390	212	2	google	google	NOUN
ajbspi-84390	212	3	scholar	scholar	NOUN
ajbspi-84390	212	4	]	]	PUNCT