American Journal Of Biomedical Science & Pharmaceutical Innovation 11 https://theusajournals.com/index.php/ajbspi VOLUME Vol.05 Issue06 2025 PAGE NO. 11-14 DOI 10.37547/ajbspi/Volume05Issue06-03 Analysis Of the Range Of Sedatives Registered In The Republic Of Uzbekistan Khasanov Farkhod Omonkulovich Assistant at Tashkent Pharmaceutical Institute, Tashkent city, Uzbekistan Kambarov Khusan Jahangirovich Professor, Doctor of Pharmaceutical Sciences, Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan Ashurov Abdurahman Akbaraliyevich Director of the Tashkent Research Institute of Vaccines and Serums, Uzbekistan Received: 14 April 2025; Accepted: 10 May 2025; Published: 17 June 2025 Abstract: This article analyzes the market of sedatives registered in the Republic of Uzbekistan. According to the State Register, the main share is accounted for by imported medicines, while the share of domestic manufacturers is about 10%. Most of the drugs registered in the country were imported from India, Pakistan, China, and Russia. The forms of medicines and market prices were also analyzed. Keywords: Sedatives, marketing analysis, State Register, dosage form, manufacturers, market analysis. Introduction: Accelerated development of the pharmaceutical industry, a significant increase in the volume of investments and exports attracted to the industry, as well as the introduction of a new management system to provide the population with high-quality, safe, and effective medicines [2]. Sedative drugs have a calming effect on the nervous system and are widely used in the treatment of stress, anxiety, and sleep disorders. Today, the demand for sedatives is growing among the population, as stress and mental fatigue are among the most common problems in the modern lifestyle[3]. Sedative medications affect the nervous system, helping to reduce stress and anxiety. According to the State Register in 2022-2025, there is a growing demand for this type of drug in Uzbekistan[1]. Analysis of registered sedative drugs in 2022-2025 shows that domestic manufacturers are increasing their market share, but imports still remain a priority[4]. This article covers market analysis and development opportunities METHODS During the analysis, data from the State Register for 2022-2025 and market analyses were studied. Manufacturers, dosage forms, and marketing strategies were evaluated using comparative analysis and statistical methods[1]. RESULTS According to the Register for 2022-2025, the main part of sedatives on the Uzbek market is supplied through imports. India, Pakistan, and China are the leaders, however, the share of domestic producers increased from 10% to 13%[1]. Table 1 Analysis of sedative drugs by country of origin Manufacturing Countries 2022 (%) 2023 (%) 2024 (%) 2025 (%) India 21 20 18 17 https://doi.org/10.37547/ajbspi/Volume05Issue06-03 https://doi.org/10.37547/ajbspi/Volume05Issue06-03 American Journal of Applied Science and Technology 12 https://theusajournals.com/index.php/ajast American Journal of Applied Science and Technology (ISSN: 2771-2745) Pakistan 15 14 14 13 Chinese 13 13 12 11 Russia 14 13 12 12 Turkey 5 6 6 6 USA 6 6 5 5 Local manufacturers 10 11 13 13 Figure 1. Share of countries producing sedatives in Uzbekistan (2025) This situation indicates a strong dependence on imports. The development of sedative production using local medicinal plants in Uzbekistan will help reduce import dependence. Analysis by dosage forms The distribution of registered sedatives by form in 2022-2025 is as follows[16]: Table 2. Drug form 2022 (%) 2023 (%) 2024 (%) 2025 (%) Syrups and tablets 50 48 47 46 Capsules and dragees 28 30 30 31 Homeopathic infusions 12 13 14 14 Liquid extracts 10 9 9 9 Analysis of sedative drugs by dosage forms in Uzbekistan (2025) Local manufacturers 17% India; 22.1% Pakistan; 16.9% China 14% Russia 16% Тurkey 8% USA 6% American Journal of Applied Science and Technology 13 https://theusajournals.com/index.php/ajast American Journal of Applied Science and Technology (ISSN: 2771-2745) Figure 2. Distribution of sedatives by forms in Uzbekistan The analysis showed that domestic manufacturers mainly produce medicines in liquid and homeopathic forms. The main reason for this is that the technology for producing liquid preparations is much simpler and more economical. Price analysis During 2022-2025, prices in the sedative market ranged from 12,000 to 310,000 soums. • The cheapest preparations are from local manufacturers. • The most expensive drugs were imported from Germany, the USA, and Russia. The prices of three sedatives for 2025 were analyzed, as a result of which it was found that Modus is the most expensive (108,000 soums), and Central-B is the cheapest (59,000 soums). The price of Vamalyan is 71,000 soums, which is in the middle range. These price differences can influence consumer choices[4]. Figure 3. Price of Sedatives (2025) It was established that imported medicines are 2.5 - 4 times more expensive than domestically produced medicines. Table 3. Cost of Sedatives (2025) Name of the drug Dosage form Average price (sum) Central-B Capsule 59 000 0 10 20 30 40 50 Syrups and tablets Capsules and dragees Homeopathic infusions Liquid extracts American Journal of Applied Science and Technology 14 https://theusajournals.com/index.php/ajast American Journal of Applied Science and Technology (ISSN: 2771-2745) Name of the drug Dosage form Average price (sum) Mode Tablet 108 000 Vamelan Capsule 71 000 CONCLUSION According to the State Register of Registered Medicines and Medical Devices in the Republic of Uzbekistan for 2022-2025, although domestic manufacturers have increased their market share, imports remain a priority. The share of domestic manufacturers is low, and mainly liquid medicines are produced. REFERENCES Approve the Resolution of the Ministry of Health of the Republic of Uzbekistan No. 26, 27, 28, 29 of the State Register of Medicines, Medical Devices and Medical Equipment Authorized for Use in Medical Practice of the Republic of Uzbekistan for 2022 - 2025. Decree of the President of the Republic of Uzbekistan, No. UP-13 (2025, January 28). Narzullaeva, I. B., & Kambarov, X. D. (2019). STUDYING THE ASSORTMENT OF SEDATIVE MEDICINES REGISTERED IN THE REPUBLIC OF UZBEKISTAN. In Economics, Business, Innovation (pp. 56-59). http://fom.uz.