American Journal of Interdisciplinary Research and Development ISSN Online: 2771-8948 Website: www.ajird.journalspark.org Volume 16, May, 2023 195 | P a g e CHEMICAL COMPOSITION AND HEALING PROPERTIES (Zingiber officinaie) Ismoilov Muminjon Yusupovich Candidate of Technical Sciences, Associate Professor, Fergana State University, Republic of Uzbekistan, Fergana Elchiyev Sardorbek Xabibullo o'g'li Graduate Student of Fergana State University Annotation This research work is devoted to the extraction of biologically active substances from the medicinal plant ginger (Zingiber officinale), amino acids in extracts and analysis of the results obtained. Keywords: medicinal plants, ginger, biologically active substance, extract, amino acids, minerals. Аннотация Настоящая исследовательская работа посвящена экстракции биологически активных веществ из лекарственного растения имбиря (Zingiber officinale), аминокислот в экстрактах и анализу полученных результатов. Ключевые слова: лекарственные растения, имбирь, биологически активные вещества, экстракт, аминокислоты, минеральные вещества. Introduction (Zingiber officinaie) is a perennial plant up to 1-2 m in height. On a straight stem are long lanceolate leaves. The rhizome is an underground storage organ in the form of palmately divided pieces, covered on top with a black thin bark, under which there is a fleshy flesh of a light yellowish hue with a slight peculiar peppery smell [1]. Adventitious roots of a fibrous type extend downward from it, and above-ground shoots extend upward. Ginger originated in South Asia, but today it is widely distributed in Asia and Europe, where it is grown outdoors in warm areas and in greenhouses and indoors in colder areas [2]. American Journal of Interdisciplinary Research and Development ISSN Online: 2771-8948 Website: www.ajird.journalspark.org Volume 16, May, 2023 196 | P a g e 1- picture Zingiber officinaie Chemical composition. The chemical composition of the rhizome determines its medicinal properties. The rhizome contains up to 3% of ginger essential oil, which gives a peculiar aroma, a large set of macro- and microelements. Of the amino acids, the chemical composition includes tryptophan, threonine, methionine, phenylalanine, valine, etc. Ginger has a high content of B, A, and C vitamins. Gingerol gives the pungent taste to ginger [3]. Ginger components zingiberene, camphene, bisabolene, citral and others in combination with amino acids and other substances create a stable therapeutic complex [4]. Ginger rhizome is used all over the world as a prophylactic and for various diseases of an anti-inflammatory and bactericidal nature, choleretic, anthelmintic, antispasmodic, for the treatment of diseases of the gastrointestinal tract, liver [5]. In East Asia, traditional healers have recommended ginger preparations to improve memory. It was considered a good natural stimulant for prolonging youth [6]. Identification of FTC-amino acids is carried out on an Agilent Technologies 1200 chromatograph on a 75x4.6 mm Discovery HS C18 column. Solution A: 0.14 M CH3COONa + 0.05% TEA pH 6.4, B: CH3CN. Flow rate 1.2 ml/min, absorbance 269nm. Gradient %B/min: 1-6%/0-2.5min; 6-30%/2.51-40min; 30-60%/40.1-45min; 60-60%/45.1-50min; 60-0%/50.1-55min. Table 1. The content of amino acids in the composition (Zingiber officinaie) № Amino acids Quantity, mg/g 1 Aspartic acid 0.894438 2 Glutamine acid 0.602388 № Amino acids Quantity, mg/g 11 Proline 0 12 Tyrosine 0.5194465 American Journal of Interdisciplinary Research and Development ISSN Online: 2771-8948 Website: www.ajird.journalspark.org Volume 16, May, 2023 197 | P a g e 3 Serene 0.678687 4 Glycine 0.658116 5 Asparagine 0.663402 6 Glutamine 0.847714 7 Cysteine 0.594109 8 Threonine 0.539624 9 argenin 0.56209 10 Alanine 0.80958 13 Valine 0.514286 14 Methionine 0.216077 15 Isoleucine 0.889492 16 Leucine 0.926678 17 Histidine 0 18 tryptophan 0.539297 19 Phenylalanine 0.162733 20 Lysine 0.613374 Σ 11.23155 mg/g According to the results, out of 20 studied amino acids in the composition (Zingiber officinaie) contains, 18 amino acids, all essential, were quite high, and the total amount of amino acids found was 11.2 mg/g. Of the 20 amino acids studied, proline and histidine were not found in ginger. The results obtained are presented in table 1. Bibliography: 1. Надер Алаа Разработка твердых лекарственных форм экстракта имбиря лекарственного // Дисс. канд. фарм. наук. – Москва, 2017. –5 с. 2. Быков И.И., Компанцев Д.В., Привалов И.М. Экстрагирование биологически активных веществ из ZINGIBER OFFICINALЕ в технологии фитопрепаратов // Вестник Смоленской Государственной медицинской академии. 2017, Т.16. №2. - 170 с. 3. Габрук Н.Г. и др. Определение интегральной антиоксидантной активноси различных экстрактов имбиря с помощью электрохимического детектирования научные ведемости // Серия Естественные науки. 2012. № 9 (128). Выпуск 19. -С. 159. 4. Габрук Н.Г., Ле Ван Тхуан. Инструментальные методы в исследовании компонентного состава биологически активных веществ имбиря (Zingiber officinale) // Научные ведомости. Серия естественные науки - 2010. №3 (74). Выпуск 10. - С. 77-82. 5. Гринько Е.Н. Исследования по стандартизации лекарственного растительного сырья, содержащего дубильные вещества // М.: Изд. Допомога, 2011 - 23 с. American Journal of Interdisciplinary Research and Development ISSN Online: 2771-8948 Website: www.ajird.journalspark.org Volume 16, May, 2023 198 | P a g e 6. Кедик С.А., Жаворонок Е.С., Седишев И.П., Панов А.В., Суслов В.В., Петрова Е.А., Сапельников М.Д., Шаталов Д.О., Еремин Д.В. Полимеры для систем доставки лекарственных веществ пролонгированного действия (Обзор). Полимеры и сополимеры молочной и гликолевой кислот //Разработка и регистрация лекарственных средств. - 2013. № 2 (3)-С. 18-36.