id	sid	tid	token	lemma	pos
american_scientific_journal-4355	1	1	american	american	PROPN
american_scientific_journal-4355	1	2	scientific	scientific	ADJ
american_scientific_journal-4355	1	3	research	research	NOUN
american_scientific_journal-4355	1	4	journal	journal	NOUN
american_scientific_journal-4355	1	5	for	for	ADP
american_scientific_journal-4355	1	6	engineering	engineering	NOUN
american_scientific_journal-4355	1	7	,	,	PUNCT
american_scientific_journal-4355	1	8	technology	technology	NOUN
american_scientific_journal-4355	1	9	,	,	PUNCT
american_scientific_journal-4355	1	10	and	and	CCONJ
american_scientific_journal-4355	1	11	sciences	science	NOUN
american_scientific_journal-4355	1	12	(	(	PUNCT
american_scientific_journal-4355	1	13	asrjets	asrjet	NOUN
american_scientific_journal-4355	1	14	)	)	PUNCT
american_scientific_journal-4355	1	15	issn	issn	PROPN
american_scientific_journal-4355	1	16	(	(	PUNCT
american_scientific_journal-4355	1	17	print	print	NOUN
american_scientific_journal-4355	1	18	)	)	PUNCT
american_scientific_journal-4355	1	19	2313	2313	NUM
american_scientific_journal-4355	1	20	-	-	SYM
american_scientific_journal-4355	1	21	4410	4410	NUM
american_scientific_journal-4355	1	22	,	,	PUNCT
american_scientific_journal-4355	1	23	issn	issn	PROPN
american_scientific_journal-4355	1	24	(	(	PUNCT
american_scientific_journal-4355	1	25	online	online	ADJ
american_scientific_journal-4355	1	26	)	)	PUNCT
american_scientific_journal-4355	1	27	2313	2313	NUM
american_scientific_journal-4355	1	28	-	-	SYM
american_scientific_journal-4355	1	29	4402	4402	NUM
american_scientific_journal-4355	1	30	©	©	PROPN
american_scientific_journal-4355	1	31	global	global	ADJ
american_scientific_journal-4355	1	32	society	society	NOUN
american_scientific_journal-4355	1	33	of	of	ADP
american_scientific_journal-4355	1	34	scientific	scientific	ADJ
american_scientific_journal-4355	1	35	research	research	NOUN
american_scientific_journal-4355	1	36	and	and	CCONJ
american_scientific_journal-4355	1	37	researchers	researcher	NOUN
american_scientific_journal-4355	1	38	http://asrjetsjournal.org/	http://asrjetsjournal.org/	PROPN
american_scientific_journal-4355	1	39	american	american	ADJ
american_scientific_journal-4355	1	40	scientific	scientific	PROPN
american_scientific_journal-4355	1	41	 	 	SPACE
american_scientific_journal-4355	1	42	research	research	NOUN
american_scientific_journal-4355	1	43	journal	journal	NOUN
american_scientific_journal-4355	1	44	for	for	ADP
american_scientific_journal-4355	1	45	engineering	engineering	NOUN
american_scientific_journal-4355	1	46	,	,	PUNCT
american_scientific_journal-4355	1	47	technology	technology	NOUN
american_scientific_journal-4355	1	48	,	,	PUNCT
american_scientific_journal-4355	1	49	and	and	CCONJ
american_scientific_journal-4355	1	50	sciences	science	NOUN
american_scientific_journal-4355	1	51	(	(	PUNCT
american_scientific_journal-4355	1	52	asrjets	asrjet	NOUN
american_scientific_journal-4355	1	53	)	)	PUNCT
american_scientific_journal-4355	1	54	(	(	PUNCT
american_scientific_journal-4355	1	55	2018	2018	NUM
american_scientific_journal-4355	1	56	)	)	PUNCT
american_scientific_journal-4355	1	57	volume	volume	NOUN
american_scientific_journal-4355	1	58	50	50	NUM
american_scientific_journal-4355	1	59	,	,	PUNCT
american_scientific_journal-4355	1	60	no	no	DET
american_scientific_journal-4355	1	61	1	1	NUM
american_scientific_journal-4355	1	62	,	,	PUNCT
american_scientific_journal-4355	1	63	pp	pp	ADV
american_scientific_journal-4355	1	64	22	22	NUM
american_scientific_journal-4355	1	65	-	-	SYM
american_scientific_journal-4355	1	66	49	49	NUM
american_scientific_journal-4355	1	67	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	1	68	as	as	ADP
american_scientific_journal-4355	1	69	a	a	DET
american_scientific_journal-4355	1	70	potential	potential	ADJ
american_scientific_journal-4355	1	71	regulator	regulator	NOUN
american_scientific_journal-4355	1	72	of	of	ADP
american_scientific_journal-4355	1	73	tgf	tgf	PROPN
american_scientific_journal-4355	1	74	-	-	PUNCT
american_scientific_journal-4355	1	75	β1	β1	PROPN
american_scientific_journal-4355	1	76	signalling	signal	VERB
american_scientific_journal-4355	1	77	in	in	ADP
american_scientific_journal-4355	1	78	the	the	DET
american_scientific_journal-4355	1	79	kidney	kidney	PROPN
american_scientific_journal-4355	1	80	dr	dr	PROPN
american_scientific_journal-4355	1	81	.	.	PROPN
american_scientific_journal-4355	1	82	mohamed	mohamed	PROPN
american_scientific_journal-4355	1	83	al	al	PROPN
american_scientific_journal-4355	1	84	-	-	PUNCT
american_scientific_journal-4355	1	85	helfawa	helfawa	PROPN
american_scientific_journal-4355	1	86	*	*	SYM
american_scientific_journal-4355	1	87	,	,	PUNCT
american_scientific_journal-4355	1	88	prof	prof	PROPN
american_scientific_journal-4355	1	89	.	.	PUNCT
american_scientific_journal-4355	1	90	aled	aled	PROPN
american_scientific_journal-4355	1	91	phiillipsb	phiillipsb	PROPN
american_scientific_journal-4355	1	92	,	,	PUNCT
american_scientific_journal-4355	2	1	dr	dr	PROPN
american_scientific_journal-4355	2	2	.	.	PROPN
american_scientific_journal-4355	2	3	robert	robert	PROPN
american_scientific_journal-4355	2	4	steadmanc	steadmanc	PROPN
american_scientific_journal-4355	2	5	.a	.a	PROPN
american_scientific_journal-4355	2	6	,	,	PUNCT
american_scientific_journal-4355	2	7	b	b	NOUN
american_scientific_journal-4355	2	8	,	,	PUNCT
american_scientific_journal-4355	2	9	cinstitute	cinstitute	NOUN
american_scientific_journal-4355	2	10	of	of	ADP
american_scientific_journal-4355	2	11	nephrology	nephrology	NOUN
american_scientific_journal-4355	2	12	.	.	PUNCT
american_scientific_journal-4355	3	1	school	school	NOUN
american_scientific_journal-4355	3	2	of	of	ADP
american_scientific_journal-4355	3	3	medicine	medicine	NOUN
american_scientific_journal-4355	3	4	.	.	PUNCT
american_scientific_journal-4355	4	1	cardiff	cardiff	PROPN
american_scientific_journal-4355	4	2	university	university	PROPN
american_scientific_journal-4355	4	3	.	.	PUNCT
american_scientific_journal-4355	5	1	heath	heath	PROPN
american_scientific_journal-4355	5	2	park	park	PROPN
american_scientific_journal-4355	5	3	cardiff	cardiff	PROPN
american_scientific_journal-4355	5	4	.	.	PUNCT
american_scientific_journal-4355	6	1	cf14	cf14	PROPN
american_scientific_journal-4355	6	2	4xn	4xn	NOUN
american_scientific_journal-4355	6	3	aemail	aemail	NOUN
american_scientific_journal-4355	6	4	:	:	PUNCT
american_scientific_journal-4355	6	5	helfawi_65@yahoo.com	helfawi_65@yahoo.com	NOUN
american_scientific_journal-4355	6	6	,	,	PUNCT
american_scientific_journal-4355	6	7	bemail	bemail	NOUN
american_scientific_journal-4355	6	8	:	:	PUNCT
american_scientific_journal-4355	6	9	phillipsao@cardiff.ac.uk	phillipsao@cardiff.ac.uk	ADJ
american_scientific_journal-4355	6	10	,	,	PUNCT
american_scientific_journal-4355	6	11	cemail	cemail	NOUN
american_scientific_journal-4355	6	12	:	:	PUNCT
american_scientific_journal-4355	6	13	steadmanr@cardiff.ac.uk	steadmanr@cardiff.ac.uk	ADJ
american_scientific_journal-4355	6	14	abstract	abstract	ADV
american_scientific_journal-4355	6	15	before	before	ADP
american_scientific_journal-4355	6	16	going	go	VERB
american_scientific_journal-4355	6	17	deeper	deep	ADJ
american_scientific_journal-4355	6	18	and	and	CCONJ
american_scientific_journal-4355	6	19	deeper	deep	ADJ
american_scientific_journal-4355	6	20	to	to	PART
american_scientific_journal-4355	6	21	study	study	VERB
american_scientific_journal-4355	6	22	the	the	DET
american_scientific_journal-4355	6	23	kidney	kidney	NOUN
american_scientific_journal-4355	6	24	and	and	CCONJ
american_scientific_journal-4355	6	25	its	its	PRON
american_scientific_journal-4355	6	26	roles	role	NOUN
american_scientific_journal-4355	6	27	,	,	PUNCT
american_scientific_journal-4355	6	28	let	let	VERB
american_scientific_journal-4355	6	29	’s	’s	PRON
american_scientific_journal-4355	6	30	explain	explain	VERB
american_scientific_journal-4355	6	31	the	the	DET
american_scientific_journal-4355	6	32	main	main	ADJ
american_scientific_journal-4355	6	33	points	point	NOUN
american_scientific_journal-4355	6	34	that	that	PRON
american_scientific_journal-4355	6	35	affects	affect	VERB
american_scientific_journal-4355	6	36	mechanisms	mechanism	NOUN
american_scientific_journal-4355	6	37	through	through	ADP
american_scientific_journal-4355	6	38	which	which	PRON
american_scientific_journal-4355	6	39	it	it	PRON
american_scientific_journal-4355	6	40	works	work	VERB
american_scientific_journal-4355	6	41	.	.	PUNCT
american_scientific_journal-4355	7	1	we	we	PRON
american_scientific_journal-4355	7	2	start	start	VERB
american_scientific_journal-4355	7	3	with	with	ADP
american_scientific_journal-4355	7	4	transforming	transform	VERB
american_scientific_journal-4355	7	5	growth	growth	NOUN
american_scientific_journal-4355	7	6	factor	factor	NOUN
american_scientific_journal-4355	7	7	β1	β1	PROPN
american_scientific_journal-4355	7	8	(	(	PUNCT
american_scientific_journal-4355	7	9	tgf	tgf	PROPN
american_scientific_journal-4355	7	10	-	-	PUNCT
american_scientific_journal-4355	7	11	β1	β1	PROPN
american_scientific_journal-4355	7	12	)	)	PUNCT
american_scientific_journal-4355	7	13	,	,	PUNCT
american_scientific_journal-4355	7	14	which	which	PRON
american_scientific_journal-4355	7	15	is	be	AUX
american_scientific_journal-4355	7	16	a	a	DET
american_scientific_journal-4355	7	17	multifunctional	multifunctional	ADJ
american_scientific_journal-4355	7	18	growth	growth	NOUN
american_scientific_journal-4355	7	19	factor	factor	NOUN
american_scientific_journal-4355	7	20	with	with	ADP
american_scientific_journal-4355	7	21	an	an	DET
american_scientific_journal-4355	7	22	important	important	ADJ
american_scientific_journal-4355	7	23	role	role	NOUN
american_scientific_journal-4355	7	24	in	in	ADP
american_scientific_journal-4355	7	25	development	development	NOUN
american_scientific_journal-4355	7	26	,	,	PUNCT
american_scientific_journal-4355	7	27	cell	cell	NOUN
american_scientific_journal-4355	7	28	proliferation	proliferation	NOUN
american_scientific_journal-4355	7	29	,	,	PUNCT
american_scientific_journal-4355	7	30	matrix	matrix	NOUN
american_scientific_journal-4355	7	31	deposition	deposition	NOUN
american_scientific_journal-4355	7	32	,	,	PUNCT
american_scientific_journal-4355	7	33	modulation	modulation	NOUN
american_scientific_journal-4355	7	34	of	of	ADP
american_scientific_journal-4355	7	35	the	the	DET
american_scientific_journal-4355	7	36	,	,	PUNCT
american_scientific_journal-4355	7	37	immunity	immunity	NOUN
american_scientific_journal-4355	7	38	,	,	PUNCT
american_scientific_journal-4355	7	39	regulation	regulation	NOUN
american_scientific_journal-4355	7	40	of	of	ADP
american_scientific_journal-4355	7	41	embryonic	embryonic	ADJ
american_scientific_journal-4355	7	42	development	development	NOUN
american_scientific_journal-4355	7	43	and	and	CCONJ
american_scientific_journal-4355	7	44	cellular	cellular	ADJ
american_scientific_journal-4355	7	45	differentiation	differentiation	NOUN
american_scientific_journal-4355	7	46	and	and	CCONJ
american_scientific_journal-4355	7	47	apoptosis	apoptosis	NOUN
american_scientific_journal-4355	7	48	(	(	PUNCT
american_scientific_journal-4355	7	49	programmed	program	VERB
american_scientific_journal-4355	7	50	cell	cell	NOUN
american_scientific_journal-4355	7	51	death	death	NOUN
american_scientific_journal-4355	7	52	)	)	PUNCT
american_scientific_journal-4355	7	53	.	.	PUNCT
american_scientific_journal-4355	8	1	it	it	PRON
american_scientific_journal-4355	8	2	is	be	AUX
american_scientific_journal-4355	8	3	considered	consider	VERB
american_scientific_journal-4355	8	4	as	as	ADP
american_scientific_journal-4355	8	5	a	a	DET
american_scientific_journal-4355	8	6	significant	significant	ADJ
american_scientific_journal-4355	8	7	mediator	mediator	NOUN
american_scientific_journal-4355	8	8	of	of	ADP
american_scientific_journal-4355	8	9	glomerular	glomerular	ADJ
american_scientific_journal-4355	8	10	and	and	CCONJ
american_scientific_journal-4355	8	11	tubulointerstitial	tubulointerstitial	ADJ
american_scientific_journal-4355	8	12	pathobiology	pathobiology	NOUN
american_scientific_journal-4355	8	13	in	in	ADP
american_scientific_journal-4355	8	14	chronic	chronic	ADJ
american_scientific_journal-4355	8	15	kidney	kidney	NOUN
american_scientific_journal-4355	8	16	diseases[1	diseases[1	NOUN
american_scientific_journal-4355	8	17	]	]	PUNCT
american_scientific_journal-4355	8	18	.	.	PUNCT
american_scientific_journal-4355	9	1	over	over	ADP
american_scientific_journal-4355	9	2	-	-	PUNCT
american_scientific_journal-4355	9	3	expression	expression	NOUN
american_scientific_journal-4355	9	4	of	of	ADP
american_scientific_journal-4355	9	5	tgf	tgf	PROPN
american_scientific_journal-4355	9	6	-	-	PUNCT
american_scientific_journal-4355	9	7	β	β	PROPN
american_scientific_journal-4355	9	8	can	can	AUX
american_scientific_journal-4355	9	9	induce	induce	VERB
american_scientific_journal-4355	9	10	renal	renal	ADJ
american_scientific_journal-4355	9	11	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	9	12	,	,	PUNCT
american_scientific_journal-4355	9	13	causing	cause	VERB
american_scientific_journal-4355	9	14	kidney	kidney	NOUN
american_scientific_journal-4355	9	15	disease	disease	NOUN
american_scientific_journal-4355	9	16	,	,	PUNCT
american_scientific_journal-4355	9	17	and	and	CCONJ
american_scientific_journal-4355	9	18	ultimately	ultimately	ADV
american_scientific_journal-4355	9	19	end	end	NOUN
american_scientific_journal-4355	9	20	-	-	PUNCT
american_scientific_journal-4355	9	21	stage	stage	NOUN
american_scientific_journal-4355	9	22	renal	renal	ADJ
american_scientific_journal-4355	9	23	disease	disease	NOUN
american_scientific_journal-4355	9	24	(	(	PUNCT
american_scientific_journal-4355	9	25	esrd	esrd	PROPN
american_scientific_journal-4355	9	26	)	)	PUNCT
american_scientific_journal-4355	9	27	.	.	PUNCT
american_scientific_journal-4355	10	1	recent	recent	ADJ
american_scientific_journal-4355	10	2	developments	development	NOUN
american_scientific_journal-4355	10	3	have	have	AUX
american_scientific_journal-4355	10	4	found	find	VERB
american_scientific_journal-4355	10	5	that	that	SCONJ
american_scientific_journal-4355	10	6	,	,	PUNCT
american_scientific_journal-4355	10	7	using	use	VERB
american_scientific_journal-4355	10	8	certain	certain	ADJ
american_scientific_journal-4355	10	9	types	type	NOUN
american_scientific_journal-4355	10	10	of	of	ADP
american_scientific_journal-4355	10	11	protein	protein	NOUN
american_scientific_journal-4355	10	12	antagonists	antagonist	NOUN
american_scientific_journal-4355	10	13	such	such	ADJ
american_scientific_journal-4355	10	14	as	as	ADP
american_scientific_journal-4355	10	15	a	a	DET
american_scientific_journal-4355	10	16	receptor	receptor	NOUN
american_scientific_journal-4355	10	17	ligand	ligand	NOUN
american_scientific_journal-4355	10	18	or	or	CCONJ
american_scientific_journal-4355	10	19	drug	drug	NOUN
american_scientific_journal-4355	10	20	that	that	PRON
american_scientific_journal-4355	10	21	does	do	AUX
american_scientific_journal-4355	10	22	not	not	PART
american_scientific_journal-4355	10	23	induce	induce	VERB
american_scientific_journal-4355	10	24	a	a	DET
american_scientific_journal-4355	10	25	biological	biological	ADJ
american_scientific_journal-4355	10	26	response	response	NOUN
american_scientific_journal-4355	10	27	itself	itself	PRON
american_scientific_journal-4355	10	28	upon	upon	SCONJ
american_scientific_journal-4355	10	29	binding	bind	VERB
american_scientific_journal-4355	10	30	to	to	ADP
american_scientific_journal-4355	10	31	a	a	DET
american_scientific_journal-4355	10	32	receptor	receptor	NOUN
american_scientific_journal-4355	10	33	but	but	CCONJ
american_scientific_journal-4355	10	34	sequential	sequential	ADJ
american_scientific_journal-4355	10	35	activation	activation	NOUN
american_scientific_journal-4355	10	36	of	of	ADP
american_scientific_journal-4355	10	37	two	two	NUM
american_scientific_journal-4355	10	38	serine	serine	NOUN
american_scientific_journal-4355	10	39	/	/	SYM
american_scientific_journal-4355	10	40	threonine	threonine	ADJ
american_scientific_journal-4355	10	41	kinase	kinase	NOUN
american_scientific_journal-4355	10	42	receptors	receptor	NOUN
american_scientific_journal-4355	10	43	,	,	PUNCT
american_scientific_journal-4355	10	44	the	the	DET
american_scientific_journal-4355	10	45	type	type	NOUN
american_scientific_journal-4355	10	46	i	i	PRON
american_scientific_journal-4355	10	47	and	and	CCONJ
american_scientific_journal-4355	10	48	type	type	NOUN
american_scientific_journal-4355	10	49	ii	ii	NOUN
american_scientific_journal-4355	10	50	receptors	receptor	NOUN
american_scientific_journal-4355	10	51	.	.	PUNCT
american_scientific_journal-4355	11	1	a	a	DET
american_scientific_journal-4355	11	2	third	third	ADJ
american_scientific_journal-4355	11	3	receptor	receptor	NOUN
american_scientific_journal-4355	11	4	,	,	PUNCT
american_scientific_journal-4355	11	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	11	6	serves	serve	VERB
american_scientific_journal-4355	11	7	as	as	ADP
american_scientific_journal-4355	11	8	a	a	DET
american_scientific_journal-4355	11	9	co	co	NOUN
american_scientific_journal-4355	11	10	-	-	NOUN
american_scientific_journal-4355	11	11	receptor	receptor	NOUN
american_scientific_journal-4355	11	12	for	for	ADP
american_scientific_journal-4355	11	13	tgf	tgf	PROPN
american_scientific_journal-4355	11	14	-	-	PUNCT
american_scientific_journal-4355	11	15	β1	β1	PROPN
american_scientific_journal-4355	11	16	.	.	PUNCT
american_scientific_journal-4355	12	1	recent	recent	ADJ
american_scientific_journal-4355	12	2	reports	report	NOUN
american_scientific_journal-4355	12	3	indicate	indicate	VERB
american_scientific_journal-4355	12	4	that	that	SCONJ
american_scientific_journal-4355	12	5	membrane	membrane	NOUN
american_scientific_journal-4355	12	6	anchored	anchor	VERB
american_scientific_journal-4355	12	7	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	12	8	may	may	AUX
american_scientific_journal-4355	12	9	play	play	VERB
american_scientific_journal-4355	12	10	an	an	DET
american_scientific_journal-4355	12	11	inhibitory	inhibitory	ADJ
american_scientific_journal-4355	12	12	role	role	NOUN
american_scientific_journal-4355	12	13	in	in	ADP
american_scientific_journal-4355	12	14	tgf	tgf	PROPN
american_scientific_journal-4355	12	15	-	-	PUNCT
american_scientific_journal-4355	12	16	β1	β1	NOUN
american_scientific_journal-4355	12	17	signalling	signalling	NOUN
american_scientific_journal-4355	12	18	.	.	PUNCT
american_scientific_journal-4355	13	1	this	this	DET
american_scientific_journal-4355	13	2	inhibitory	inhibitory	ADJ
american_scientific_journal-4355	13	3	role	role	NOUN
american_scientific_journal-4355	13	4	of	of	ADP
american_scientific_journal-4355	13	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	13	6	is	be	AUX
american_scientific_journal-4355	13	7	a	a	DET
american_scientific_journal-4355	13	8	function	function	NOUN
american_scientific_journal-4355	13	9	of	of	ADP
american_scientific_journal-4355	13	10	the	the	DET
american_scientific_journal-4355	13	11	heparan	heparan	ADJ
american_scientific_journal-4355	13	12	sulphate	sulphate	NOUN
american_scientific_journal-4355	13	13	composition	composition	NOUN
american_scientific_journal-4355	13	14	of	of	ADP
american_scientific_journal-4355	13	15	the	the	DET
american_scientific_journal-4355	13	16	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	13	17	glycosaminoglycan	glycosaminoglycan	NOUN
american_scientific_journal-4355	14	1	[	[	X
american_scientific_journal-4355	14	2	2	2	NUM
american_scientific_journal-4355	14	3	]	]	PUNCT
american_scientific_journal-4355	14	4	.	.	PUNCT
american_scientific_journal-4355	15	1	we	we	PRON
american_scientific_journal-4355	15	2	can	can	AUX
american_scientific_journal-4355	15	3	say	say	VERB
american_scientific_journal-4355	15	4	that	that	SCONJ
american_scientific_journal-4355	15	5	,	,	PUNCT
american_scientific_journal-4355	15	6	the	the	DET
american_scientific_journal-4355	15	7	expression	expression	NOUN
american_scientific_journal-4355	15	8	of	of	ADP
american_scientific_journal-4355	15	9	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	15	10	and	and	CCONJ
american_scientific_journal-4355	15	11	its	its	PRON
american_scientific_journal-4355	15	12	augmentation	augmentation	NOUN
american_scientific_journal-4355	15	13	by	by	ADP
american_scientific_journal-4355	15	14	cytokines	cytokine	NOUN
american_scientific_journal-4355	15	15	treatment	treatment	NOUN
american_scientific_journal-4355	15	16	in	in	ADP
american_scientific_journal-4355	15	17	hk2	hk2	PROPN
american_scientific_journal-4355	15	18	cells	cell	NOUN
american_scientific_journal-4355	15	19	has	have	AUX
american_scientific_journal-4355	15	20	been	be	AUX
american_scientific_journal-4355	15	21	described	describe	VERB
american_scientific_journal-4355	15	22	.	.	PUNCT
american_scientific_journal-4355	16	1	by	by	ADP
american_scientific_journal-4355	16	2	concentrating	concentrate	VERB
american_scientific_journal-4355	16	3	on	on	ADP
american_scientific_journal-4355	16	4	tgf	tgf	PROPN
american_scientific_journal-4355	16	5	-	-	PUNCT
american_scientific_journal-4355	16	6	β	β	NOUN
american_scientific_journal-4355	16	7	activity	activity	NOUN
american_scientific_journal-4355	16	8	,	,	PUNCT
american_scientific_journal-4355	16	9	it	it	PRON
american_scientific_journal-4355	16	10	is	be	AUX
american_scientific_journal-4355	16	11	shown	show	VERB
american_scientific_journal-4355	16	12	that	that	SCONJ
american_scientific_journal-4355	16	13	knock	knock	NOUN
american_scientific_journal-4355	16	14	-	-	PUNCT
american_scientific_journal-4355	16	15	down	down	NOUN
american_scientific_journal-4355	16	16	by	by	ADP
american_scientific_journal-4355	16	17	sirna	sirna	PROPN
american_scientific_journal-4355	16	18	and	and	CCONJ
american_scientific_journal-4355	16	19	inhibition	inhibition	NOUN
american_scientific_journal-4355	16	20	of	of	ADP
american_scientific_journal-4355	16	21	glycoslation	glycoslation	NOUN
american_scientific_journal-4355	16	22	of	of	ADP
american_scientific_journal-4355	16	23	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	16	24	antagonize	antagonize	VERB
american_scientific_journal-4355	16	25	signalling	signal	VERB
american_scientific_journal-4355	16	26	by	by	ADP
american_scientific_journal-4355	16	27	tgf	tgf	PROPN
american_scientific_journal-4355	16	28	-	-	PUNCT
american_scientific_journal-4355	16	29	β	β	PROPN
american_scientific_journal-4355	16	30	end	end	NOUN
american_scientific_journal-4355	16	31	production	production	NOUN
american_scientific_journal-4355	16	32	of	of	ADP
american_scientific_journal-4355	16	33	emt	emt	PROPN
american_scientific_journal-4355	16	34	.	.	PUNCT
american_scientific_journal-4355	17	1	this	this	DET
american_scientific_journal-4355	17	2	work	work	NOUN
american_scientific_journal-4355	17	3	suggests	suggest	VERB
american_scientific_journal-4355	17	4	that	that	SCONJ
american_scientific_journal-4355	17	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	17	6	could	could	AUX
american_scientific_journal-4355	17	7	be	be	AUX
american_scientific_journal-4355	17	8	a	a	DET
american_scientific_journal-4355	17	9	major	major	ADJ
american_scientific_journal-4355	17	10	mediator	mediator	NOUN
american_scientific_journal-4355	17	11	of	of	ADP
american_scientific_journal-4355	17	12	ptc	ptc	PROPN
american_scientific_journal-4355	17	13	activation	activation	NOUN
american_scientific_journal-4355	17	14	in	in	ADP
american_scientific_journal-4355	17	15	vivo	vivo	NOUN
american_scientific_journal-4355	17	16	.	.	PUNCT
american_scientific_journal-4355	18	1	blocks	block	NOUN
american_scientific_journal-4355	18	2	reverse	reverse	VERB
american_scientific_journal-4355	18	3	the	the	DET
american_scientific_journal-4355	18	4	effects	effect	NOUN
american_scientific_journal-4355	18	5	of	of	ADP
american_scientific_journal-4355	18	6	renal	renal	ADJ
american_scientific_journal-4355	18	7	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	18	8	[	[	X
american_scientific_journal-4355	18	9	3	3	NUM
american_scientific_journal-4355	18	10	]	]	PUNCT
american_scientific_journal-4355	18	11	.	.	PUNCT
american_scientific_journal-4355	19	1	keywords	keyword	NOUN
american_scientific_journal-4355	19	2	:	:	PUNCT
american_scientific_journal-4355	19	3	α	α	X
american_scientific_journal-4355	19	4	-	-	PUNCT
american_scientific_journal-4355	19	5	sma;(alphasmooth	sma;(alphasmooth	ADJ
american_scientific_journal-4355	19	6	muscle	muscle	NOUN
american_scientific_journal-4355	19	7	actin	actin	NOUN
american_scientific_journal-4355	19	8	)	)	PUNCT
american_scientific_journal-4355	19	9	.	.	PUNCT
american_scientific_journal-4355	20	1	dna	dna	PROPN
american_scientific_journal-4355	20	2	;	;	PUNCT
american_scientific_journal-4355	20	3	(	(	PUNCT
american_scientific_journal-4355	20	4	deoxyribonucleic	deoxyribonucleic	ADJ
american_scientific_journal-4355	20	5	acid	acid	NOUN
american_scientific_journal-4355	20	6	)	)	PUNCT
american_scientific_journal-4355	20	7	.	.	PUNCT
american_scientific_journal-4355	21	1	ecm	ecm	NOUN
american_scientific_journal-4355	21	2	;	;	PUNCT
american_scientific_journal-4355	21	3	(	(	PUNCT
american_scientific_journal-4355	21	4	extracellular	extracellular	ADJ
american_scientific_journal-4355	21	5	matrix	matrix	NOUN
american_scientific_journal-4355	21	6	)	)	PUNCT
american_scientific_journal-4355	21	7	.	.	PUNCT
american_scientific_journal-4355	22	1	emt	emt	PROPN
american_scientific_journal-4355	22	2	;	;	PUNCT
american_scientific_journal-4355	22	3	(	(	PUNCT
american_scientific_journal-4355	22	4	epithelial	epithelial	ADJ
american_scientific_journal-4355	22	5	-	-	PUNCT
american_scientific_journal-4355	22	6	mesenchymal	mesenchymal	NOUN
american_scientific_journal-4355	22	7	transition	transition	NOUN
american_scientific_journal-4355	22	8	)	)	PUNCT
american_scientific_journal-4355	22	9	.	.	PUNCT
american_scientific_journal-4355	23	1	gapdh	gapdh	NOUN
american_scientific_journal-4355	23	2	;	;	PUNCT
american_scientific_journal-4355	23	3	(	(	PUNCT
american_scientific_journal-4355	23	4	glyceraldehyde-3	glyceraldehyde-3	VERB
american_scientific_journal-4355	23	5	-	-	ADJ
american_scientific_journal-4355	23	6	phosphate	phosphate	ADJ
american_scientific_journal-4355	23	7	dehydrogenase	dehydrogenase	NOUN
american_scientific_journal-4355	23	8	)	)	PUNCT
american_scientific_journal-4355	23	9	.	.	PUNCT
american_scientific_journal-4355	23	10	hk-2	hk-2	PUNCT
american_scientific_journal-4355	24	1	(	(	PUNCT
american_scientific_journal-4355	24	2	human	human	NOUN
american_scientific_journal-4355	24	3	kidney-2	kidney-2	PROPN
american_scientific_journal-4355	24	4	)	)	PUNCT
american_scientific_journal-4355	24	5	.	.	PUNCT
american_scientific_journal-4355	25	1	mrna	mrna	PROPN
american_scientific_journal-4355	25	2	;	;	PUNCT
american_scientific_journal-4355	25	3	(	(	PUNCT
american_scientific_journal-4355	25	4	messenger	messenger	NOUN
american_scientific_journal-4355	25	5	ribonucleic	ribonucleic	ADJ
american_scientific_journal-4355	25	6	acid	acid	NOUN
american_scientific_journal-4355	25	7	)	)	PUNCT
american_scientific_journal-4355	25	8	.	.	PUNCT
american_scientific_journal-4355	26	1	page	page	NOUN
american_scientific_journal-4355	26	2	;	;	PUNCT
american_scientific_journal-4355	26	3	(	(	PUNCT
american_scientific_journal-4355	26	4	polyacrylamide	polyacrylamide	NOUN
american_scientific_journal-4355	26	5	gel	gel	NOUN
american_scientific_journal-4355	26	6	electrophoresis	electrophoresis	NOUN
american_scientific_journal-4355	26	7	)	)	PUNCT
american_scientific_journal-4355	26	8	.	.	PUNCT
american_scientific_journal-4355	27	1	pcr	pcr	PROPN
american_scientific_journal-4355	27	2	;	;	PUNCT
american_scientific_journal-4355	27	3	(	(	PUNCT
american_scientific_journal-4355	27	4	polymerase	polymerase	NOUN
american_scientific_journal-4355	27	5	chain	chain	NOUN
american_scientific_journal-4355	27	6	reaction	reaction	NOUN
american_scientific_journal-4355	27	7	)	)	PUNCT
american_scientific_journal-4355	27	8	.	.	PUNCT
american_scientific_journal-4355	28	1	p	p	X
american_scientific_journal-4355	28	2	-	-	PUNCT
american_scientific_journal-4355	28	3	smad;(phosphorylated	smad;(phosphorylate	VERB
american_scientific_journal-4355	28	4	-	-	PUNCT
american_scientific_journal-4355	28	5	smad	smad	NOUN
american_scientific_journal-4355	28	6	)	)	PUNCT
american_scientific_journal-4355	28	7	.	.	PUNCT
american_scientific_journal-4355	29	1	qpcr	qpcr	ADV
american_scientific_journal-4355	29	2	;	;	PUNCT
american_scientific_journal-4355	29	3	(	(	PUNCT
american_scientific_journal-4355	29	4	quantitative	quantitative	ADJ
american_scientific_journal-4355	29	5	pcr	pcr	NOUN
american_scientific_journal-4355	29	6	)	)	PUNCT
american_scientific_journal-4355	29	7	.	.	PUNCT
american_scientific_journal-4355	30	1	rna	rna	NOUN
american_scientific_journal-4355	30	2	;	;	PUNCT
american_scientific_journal-4355	30	3	(	(	PUNCT
american_scientific_journal-4355	30	4	ribonucleic	ribonucleic	ADJ
american_scientific_journal-4355	30	5	acid	acid	NOUN
american_scientific_journal-4355	30	6	)	)	PUNCT
american_scientific_journal-4355	30	7	.	.	PUNCT
american_scientific_journal-4355	31	1	rtpcr	rtpcr	PROPN
american_scientific_journal-4355	31	2	;	;	PUNCT
american_scientific_journal-4355	31	3	(	(	PUNCT
american_scientific_journal-4355	31	4	reverse	reverse	VERB
american_scientific_journal-4355	31	5	transcriptase	transcriptase	NOUN
american_scientific_journal-4355	31	6	-	-	PUNCT
american_scientific_journal-4355	31	7	pcr	pcr	ADJ
american_scientific_journal-4355	31	8	)	)	PUNCT
american_scientific_journal-4355	31	9	.	.	PUNCT
american_scientific_journal-4355	32	1	tgf	tgf	PROPN
american_scientific_journal-4355	32	2	-	-	PUNCT
american_scientific_journal-4355	32	3	β	β	PROPN
american_scientific_journal-4355	32	4	;	;	PUNCT
american_scientific_journal-4355	32	5	(	(	PUNCT
american_scientific_journal-4355	32	6	transforming	transform	VERB
american_scientific_journal-4355	32	7	growth	growth	NOUN
american_scientific_journal-4355	32	8	factor	factor	NOUN
american_scientific_journal-4355	32	9	-	-	PUNCT
american_scientific_journal-4355	32	10	beta	beta	NOUN
american_scientific_journal-4355	32	11	)	)	PUNCT
american_scientific_journal-4355	32	12	.	.	PUNCT
american_scientific_journal-4355	33	1	-----------------------------------------------------------------------	-----------------------------------------------------------------------	PUNCT
american_scientific_journal-4355	33	2	*	*	PUNCT
american_scientific_journal-4355	33	3	corresponding	correspond	VERB
american_scientific_journal-4355	33	4	author	author	NOUN
american_scientific_journal-4355	33	5	.	.	PUNCT
american_scientific_journal-4355	34	1	1	1	X
american_scientific_journal-4355	34	2	.	.	X
american_scientific_journal-4355	34	3	introduction	introduction	NOUN
american_scientific_journal-4355	34	4	tubulointerstitial	tubulointerstitial	ADJ
american_scientific_journal-4355	34	5	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	34	6	is	be	AUX
american_scientific_journal-4355	34	7	a	a	DET
american_scientific_journal-4355	34	8	well	well	ADV
american_scientific_journal-4355	34	9	-	-	PUNCT
american_scientific_journal-4355	34	10	known	know	VERB
american_scientific_journal-4355	34	11	finding	finding	NOUN
american_scientific_journal-4355	34	12	of	of	ADP
american_scientific_journal-4355	34	13	chronic	chronic	ADJ
american_scientific_journal-4355	34	14	renal	renal	ADJ
american_scientific_journal-4355	34	15	disease	disease	NOUN
american_scientific_journal-4355	34	16	,	,	PUNCT
american_scientific_journal-4355	34	17	irrespective	irrespective	ADV
american_scientific_journal-4355	34	18	of	of	ADP
american_scientific_journal-4355	34	19	the	the	DET
american_scientific_journal-4355	34	20	aetiology	aetiology	NOUN
american_scientific_journal-4355	34	21	of	of	ADP
american_scientific_journal-4355	34	22	the	the	DET
american_scientific_journal-4355	34	23	diseases	disease	NOUN
american_scientific_journal-4355	34	24	and	and	CCONJ
american_scientific_journal-4355	34	25	is	be	AUX
american_scientific_journal-4355	34	26	considered	consider	VERB
american_scientific_journal-4355	34	27	as	as	ADP
american_scientific_journal-4355	34	28	the	the	DET
american_scientific_journal-4355	34	29	major	major	ADJ
american_scientific_journal-4355	34	30	lesion	lesion	NOUN
american_scientific_journal-4355	34	31	of	of	ADP
american_scientific_journal-4355	34	32	end	end	NOUN
american_scientific_journal-4355	34	33	-	-	PUNCT
american_scientific_journal-4355	34	34	stage	stage	NOUN
american_scientific_journal-4355	34	35	renal	renal	ADJ
american_scientific_journal-4355	34	36	diseases	disease	NOUN
american_scientific_journal-4355	34	37	such	such	ADJ
american_scientific_journal-4355	34	38	as	as	ADP
american_scientific_journal-4355	34	39	glomerulonephritis	glomerulonephritis	NOUN
american_scientific_journal-4355	34	40	as	as	ADP
american_scientific_journal-4355	34	41	a	a	DET
american_scientific_journal-4355	34	42	primary	primary	ADJ
american_scientific_journal-4355	34	43	inflammation	inflammation	NOUN
american_scientific_journal-4355	34	44	,	,	PUNCT
american_scientific_journal-4355	34	45	diabetic	diabetic	ADJ
american_scientific_journal-4355	34	46	nephropathy	nephropathy	NOUN
american_scientific_journal-4355	34	47	as	as	ADP
american_scientific_journal-4355	34	48	a	a	DET
american_scientific_journal-4355	34	49	metabolic	metabolic	NOUN
american_scientific_journal-4355	34	50	dysfunction	dysfunction	NOUN
american_scientific_journal-4355	34	51	,	,	PUNCT
american_scientific_journal-4355	34	52	and	and	CCONJ
american_scientific_journal-4355	34	53	cystic	cystic	ADJ
american_scientific_journal-4355	34	54	nephropathy	nephropathy	NOUN
american_scientific_journal-4355	34	55	as	as	ADP
american_scientific_journal-4355	34	56	structural	structural	ADJ
american_scientific_journal-4355	34	57	malformations	malformation	NOUN
american_scientific_journal-4355	34	58	.	.	PUNCT
american_scientific_journal-4355	35	1	the	the	DET
american_scientific_journal-4355	35	2	normal	normal	ADJ
american_scientific_journal-4355	35	3	interstitium	interstitium	NOUN
american_scientific_journal-4355	35	4	is	be	AUX
american_scientific_journal-4355	35	5	a	a	DET
american_scientific_journal-4355	35	6	complicated	complicated	ADJ
american_scientific_journal-4355	35	7	structure	structure	NOUN
american_scientific_journal-4355	35	8	of	of	ADP
american_scientific_journal-4355	35	9	collagen	collagen	NOUN
american_scientific_journal-4355	35	10	,	,	PUNCT
american_scientific_journal-4355	35	11	fibronectin	fibronectin	NOUN
american_scientific_journal-4355	35	12	,	,	PUNCT
american_scientific_journal-4355	35	13	non	non	ADJ
american_scientific_journal-4355	35	14	-	-	ADJ
american_scientific_journal-4355	35	15	collagenous	collagenous	ADJ
american_scientific_journal-4355	35	16	glycoproteins	glycoprotein	NOUN
american_scientific_journal-4355	35	17	and	and	CCONJ
american_scientific_journal-4355	35	18	proteoglycans	proteoglycan	NOUN
american_scientific_journal-4355	35	19	.	.	PUNCT
american_scientific_journal-4355	36	1	interstitial	interstitial	ADJ
american_scientific_journal-4355	36	2	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	36	3	is	be	AUX
american_scientific_journal-4355	36	4	characterized	characterize	VERB
american_scientific_journal-4355	36	5	by	by	ADP
american_scientific_journal-4355	36	6	excessive	excessive	ADJ
american_scientific_journal-4355	36	7	synthesis	synthesis	NOUN
american_scientific_journal-4355	36	8	and	and	CCONJ
american_scientific_journal-4355	36	9	accumulation	accumulation	NOUN
american_scientific_journal-4355	36	10	of	of	ADP
american_scientific_journal-4355	36	11	these	these	DET
american_scientific_journal-4355	36	12	and	and	CCONJ
american_scientific_journal-4355	36	13	other	other	ADJ
american_scientific_journal-4355	36	14	ecm	ecm	NOUN
american_scientific_journal-4355	36	15	substances	substance	NOUN
american_scientific_journal-4355	36	16	[	[	X
american_scientific_journal-4355	36	17	4	4	NUM
american_scientific_journal-4355	36	18	]	]	PUNCT
american_scientific_journal-4355	36	19	.	.	PUNCT
american_scientific_journal-4355	37	1	thus	thus	ADV
american_scientific_journal-4355	37	2	the	the	DET
american_scientific_journal-4355	37	3	intersitium	intersitium	NOUN
american_scientific_journal-4355	37	4	expands	expand	VERB
american_scientific_journal-4355	37	5	causing	cause	VERB
american_scientific_journal-4355	37	6	derangement	derangement	NOUN
american_scientific_journal-4355	37	7	of	of	ADP
american_scientific_journal-4355	37	8	tubulointerstitial	tubulointerstitial	ADJ
american_scientific_journal-4355	37	9	structure	structure	NOUN
american_scientific_journal-4355	37	10	and	and	CCONJ
american_scientific_journal-4355	37	11	changes	change	NOUN
american_scientific_journal-4355	37	12	of	of	ADP
american_scientific_journal-4355	37	13	the	the	DET
american_scientific_journal-4355	37	14	normal	normal	ADJ
american_scientific_journal-4355	37	15	physiological	physiological	ADJ
american_scientific_journal-4355	37	16	function	function	NOUN
american_scientific_journal-4355	37	17	and	and	CCONJ
american_scientific_journal-4355	37	18	subsequently	subsequently	ADV
american_scientific_journal-4355	37	19	gradual	gradual	ADJ
american_scientific_journal-4355	37	20	deterioration	deterioration	NOUN
american_scientific_journal-4355	37	21	of	of	ADP
american_scientific_journal-4355	37	22	renal	renal	ADJ
american_scientific_journal-4355	37	23	function	function	NOUN
american_scientific_journal-4355	37	24	.	.	PUNCT
american_scientific_journal-4355	38	1	progressive	progressive	ADJ
american_scientific_journal-4355	38	2	loss	loss	NOUN
american_scientific_journal-4355	38	3	of	of	ADP
american_scientific_journal-4355	38	4	renal	renal	ADJ
american_scientific_journal-4355	38	5	function	function	NOUN
american_scientific_journal-4355	38	6	is	be	AUX
american_scientific_journal-4355	38	7	associated	associate	VERB
american_scientific_journal-4355	38	8	with	with	ADP
american_scientific_journal-4355	38	9	development	development	NOUN
american_scientific_journal-4355	38	10	of	of	ADP
american_scientific_journal-4355	38	11	glomerulosclerosis	glomerulosclerosis	NOUN
american_scientific_journal-4355	38	12	and	and	CCONJ
american_scientific_journal-4355	38	13	with	with	ADP
american_scientific_journal-4355	38	14	interstitial	interstitial	ADJ
american_scientific_journal-4355	38	15	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	38	16	as	as	ADV
american_scientific_journal-4355	38	17	well	well	ADV
american_scientific_journal-4355	38	18	.	.	PUNCT
american_scientific_journal-4355	39	1	interstitial	interstitial	ADJ
american_scientific_journal-4355	39	2	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	39	3	is	be	AUX
american_scientific_journal-4355	39	4	characterized	characterize	VERB
american_scientific_journal-4355	39	5	by	by	ADP
american_scientific_journal-4355	39	6	the	the	DET
american_scientific_journal-4355	39	7	destruction	destruction	NOUN
american_scientific_journal-4355	39	8	of	of	ADP
american_scientific_journal-4355	39	9	renal	renal	ADJ
american_scientific_journal-4355	39	10	tubules	tubule	NOUN
american_scientific_journal-4355	39	11	and	and	CCONJ
american_scientific_journal-4355	39	12	interstitial	interstitial	ADJ
american_scientific_journal-4355	39	13	capillaries	capillary	NOUN
american_scientific_journal-4355	39	14	as	as	ADV
american_scientific_journal-4355	39	15	well	well	ADV
american_scientific_journal-4355	39	16	as	as	ADP
american_scientific_journal-4355	39	17	by	by	ADP
american_scientific_journal-4355	39	18	the	the	DET
american_scientific_journal-4355	39	19	accumulation	accumulation	NOUN
american_scientific_journal-4355	39	20	of	of	ADP
american_scientific_journal-4355	39	21	extracellular	extracellular	ADJ
american_scientific_journal-4355	39	22	matrix	matrix	NOUN
american_scientific_journal-4355	39	23	proteins	protein	NOUN
american_scientific_journal-4355	39	24	[	[	X
american_scientific_journal-4355	39	25	5	5	NUM
american_scientific_journal-4355	39	26	]	]	PUNCT
american_scientific_journal-4355	39	27	.	.	PUNCT
american_scientific_journal-4355	40	1	as	as	ADP
american_scientific_journal-4355	40	2	inerstitial	inerstitial	ADJ
american_scientific_journal-4355	40	3	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	40	4	,	,	PUNCT
american_scientific_journal-4355	40	5	related	relate	VERB
american_scientific_journal-4355	40	6	to	to	ADP
american_scientific_journal-4355	40	7	accumulation	accumulation	NOUN
american_scientific_journal-4355	40	8	of	of	ADP
american_scientific_journal-4355	40	9	ecm	ecm	NOUN
american_scientific_journal-4355	40	10	,	,	PUNCT
american_scientific_journal-4355	40	11	it	it	PRON
american_scientific_journal-4355	40	12	also	also	ADV
american_scientific_journal-4355	40	13	related	relate	VERB
american_scientific_journal-4355	40	14	to	to	ADP
american_scientific_journal-4355	40	15	progression	progression	NOUN
american_scientific_journal-4355	40	16	of	of	ADP
american_scientific_journal-4355	40	17	renal	renal	ADJ
american_scientific_journal-4355	40	18	disease	disease	NOUN
american_scientific_journal-4355	40	19	with	with	ADP
american_scientific_journal-4355	40	20	accumulation	accumulation	NOUN
american_scientific_journal-4355	40	21	of	of	ADP
american_scientific_journal-4355	40	22	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	40	23	and	and	CCONJ
american_scientific_journal-4355	40	24	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	40	25	which	which	PRON
american_scientific_journal-4355	40	26	is	be	AUX
american_scientific_journal-4355	40	27	related	relate	VERB
american_scientific_journal-4355	40	28	to	to	PART
american_scientific_journal-4355	40	29	nephron	nephron	VERB
american_scientific_journal-4355	40	30	loss	loss	NOUN
american_scientific_journal-4355	40	31	and	and	CCONJ
american_scientific_journal-4355	40	32	kidney	kidney	NOUN
american_scientific_journal-4355	40	33	shut	shut	VERB
american_scientific_journal-4355	40	34	down	down	ADP
american_scientific_journal-4355	40	35	,	,	PUNCT
american_scientific_journal-4355	40	36	so	so	ADV
american_scientific_journal-4355	40	37	considered	consider	VERB
american_scientific_journal-4355	40	38	as	as	ADP
american_scientific_journal-4355	40	39	a	a	DET
american_scientific_journal-4355	40	40	predictor	predictor	NOUN
american_scientific_journal-4355	40	41	of	of	ADP
american_scientific_journal-4355	40	42	fibrotic	fibrotic	ADJ
american_scientific_journal-4355	40	43	progression	progression	NOUN
american_scientific_journal-4355	41	1	[	[	X
american_scientific_journal-4355	41	2	6	6	NUM
american_scientific_journal-4355	41	3	]	]	PUNCT
american_scientific_journal-4355	41	4	.	.	PUNCT
american_scientific_journal-4355	42	1	moreover	moreover	ADV
american_scientific_journal-4355	42	2	,	,	PUNCT
american_scientific_journal-4355	42	3	previous	previous	ADJ
american_scientific_journal-4355	42	4	studies	study	NOUN
american_scientific_journal-4355	42	5	have	have	AUX
american_scientific_journal-4355	42	6	shown	show	VERB
american_scientific_journal-4355	42	7	that	that	DET
american_scientific_journal-4355	42	8	reduction	reduction	NOUN
american_scientific_journal-4355	42	9	in	in	ADP
american_scientific_journal-4355	42	10	the	the	DET
american_scientific_journal-4355	42	11	glomerular	glomerular	ADJ
american_scientific_journal-4355	42	12	filtration	filtration	NOUN
american_scientific_journal-4355	42	13	rate	rate	NOUN
american_scientific_journal-4355	42	14	is	be	AUX
american_scientific_journal-4355	42	15	better	well	ADV
american_scientific_journal-4355	42	16	correlated	correlate	VERB
american_scientific_journal-4355	42	17	with	with	ADP
american_scientific_journal-4355	42	18	tubulointerstitial	tubulointerstitial	ADJ
american_scientific_journal-4355	42	19	injury	injury	NOUN
american_scientific_journal-4355	42	20	than	than	ADP
american_scientific_journal-4355	42	21	with	with	ADP
american_scientific_journal-4355	42	22	glomerulosclerosis	glomerulosclerosis	NOUN
american_scientific_journal-4355	42	23	)	)	PUNCT
american_scientific_journal-4355	43	1	[	[	X
american_scientific_journal-4355	43	2	7	7	NUM
american_scientific_journal-4355	43	3	]	]	PUNCT
american_scientific_journal-4355	43	4	.	.	PUNCT
american_scientific_journal-4355	44	1	several	several	ADJ
american_scientific_journal-4355	44	2	factors	factor	NOUN
american_scientific_journal-4355	44	3	,	,	PUNCT
american_scientific_journal-4355	44	4	including	include	VERB
american_scientific_journal-4355	44	5	cytokines	cytokine	NOUN
american_scientific_journal-4355	44	6	and	and	CCONJ
american_scientific_journal-4355	44	7	growth	growth	NOUN
american_scientific_journal-4355	44	8	factors	factor	NOUN
american_scientific_journal-4355	44	9	such	such	ADJ
american_scientific_journal-4355	44	10	as	as	ADP
american_scientific_journal-4355	44	11	transforming	transform	VERB
american_scientific_journal-4355	44	12	growth	growth	NOUN
american_scientific_journal-4355	44	13	factor	factor	NOUN
american_scientific_journal-4355	44	14	βi	βi	PROPN
american_scientific_journal-4355	44	15	(	(	PUNCT
american_scientific_journal-4355	44	16	tgf	tgf	PROPN
american_scientific_journal-4355	44	17	-	-	PUNCT
american_scientific_journal-4355	44	18	βi	βi	PROPN
american_scientific_journal-4355	44	19	)	)	PUNCT
american_scientific_journal-4355	44	20	activate	activate	VERB
american_scientific_journal-4355	44	21	tubular	tubular	ADJ
american_scientific_journal-4355	44	22	cells	cell	NOUN
american_scientific_journal-4355	44	23	and	and	CCONJ
american_scientific_journal-4355	44	24	lead	lead	VERB
american_scientific_journal-4355	44	25	to	to	ADP
american_scientific_journal-4355	44	26	this	this	DET
american_scientific_journal-4355	44	27	pathogenesis	pathogenesis	NOUN
american_scientific_journal-4355	44	28	.	.	PUNCT
american_scientific_journal-4355	45	1	activated	activate	VERB
american_scientific_journal-4355	45	2	tubular	tubular	ADJ
american_scientific_journal-4355	45	3	cells	cell	NOUN
american_scientific_journal-4355	45	4	secrete	secrete	VERB
american_scientific_journal-4355	45	5	increased	increase	VERB
american_scientific_journal-4355	45	6	amounts	amount	NOUN
american_scientific_journal-4355	45	7	of	of	ADP
american_scientific_journal-4355	45	8	chemokines	chemokine	NOUN
american_scientific_journal-4355	45	9	and	and	CCONJ
american_scientific_journal-4355	45	10	cytokines	cytokine	NOUN
american_scientific_journal-4355	45	11	into	into	ADP
american_scientific_journal-4355	45	12	the	the	DET
american_scientific_journal-4355	45	13	peritubular	peritubular	ADJ
american_scientific_journal-4355	45	14	interstitium	interstitium	NOUN
american_scientific_journal-4355	45	15	.	.	PUNCT
american_scientific_journal-4355	46	1	activated	activate	VERB
american_scientific_journal-4355	46	2	tubular	tubular	ADJ
american_scientific_journal-4355	46	3	cells	cell	NOUN
american_scientific_journal-4355	46	4	may	may	AUX
american_scientific_journal-4355	46	5	themselves	themselves	PRON
american_scientific_journal-4355	46	6	increase	increase	VERB
american_scientific_journal-4355	46	7	the	the	DET
american_scientific_journal-4355	46	8	formation	formation	NOUN
american_scientific_journal-4355	46	9	of	of	ADP
american_scientific_journal-4355	46	10	peritubular	peritubular	ADJ
american_scientific_journal-4355	46	11	extracellular	extracellular	ADJ
american_scientific_journal-4355	46	12	matrix	matrix	NOUN
american_scientific_journal-4355	46	13	as	as	ADV
american_scientific_journal-4355	46	14	well	well	ADV
american_scientific_journal-4355	46	15	[	[	X
american_scientific_journal-4355	46	16	8	8	NUM
american_scientific_journal-4355	46	17	]	]	SYM
american_scientific_journal-4355	46	18	.	.	PUNCT
american_scientific_journal-4355	47	1	immune	immune	ADJ
american_scientific_journal-4355	47	2	responses	response	NOUN
american_scientific_journal-4355	47	3	of	of	ADP
american_scientific_journal-4355	47	4	tubular	tubular	ADJ
american_scientific_journal-4355	47	5	epithelial	epithelial	ADJ
american_scientific_journal-4355	47	6	cells	cell	NOUN
american_scientific_journal-4355	47	7	are	be	AUX
american_scientific_journal-4355	47	8	induced	induce	VERB
american_scientific_journal-4355	47	9	by	by	ADP
american_scientific_journal-4355	47	10	exposure	exposure	NOUN
american_scientific_journal-4355	47	11	to	to	ADP
american_scientific_journal-4355	47	12	proteins	protein	NOUN
american_scientific_journal-4355	47	13	e.g.	e.g.	ADV
american_scientific_journal-4355	47	14	stimulation	stimulation	NOUN
american_scientific_journal-4355	47	15	of	of	ADP
american_scientific_journal-4355	47	16	the	the	DET
american_scientific_journal-4355	47	17	release	release	NOUN
american_scientific_journal-4355	47	18	of	of	ADP
american_scientific_journal-4355	47	19	various	various	ADJ
american_scientific_journal-4355	47	20	cytokines	cytokine	NOUN
american_scientific_journal-4355	47	21	,	,	PUNCT
american_scientific_journal-4355	47	22	including	include	VERB
american_scientific_journal-4355	47	23	tgf	tgf	PROPN
american_scientific_journal-4355	47	24	-	-	PUNCT
american_scientific_journal-4355	47	25	β1[9	β1[9	PROPN
american_scientific_journal-4355	47	26	]	]	PUNCT
american_scientific_journal-4355	47	27	.	.	PUNCT
american_scientific_journal-4355	48	1	the	the	DET
american_scientific_journal-4355	48	2	release	release	NOUN
american_scientific_journal-4355	48	3	of	of	ADP
american_scientific_journal-4355	48	4	such	such	ADJ
american_scientific_journal-4355	48	5	cytokines	cytokine	NOUN
american_scientific_journal-4355	48	6	causes	cause	VERB
american_scientific_journal-4355	48	7	differentiation	differentiation	NOUN
american_scientific_journal-4355	48	8	of	of	ADP
american_scientific_journal-4355	48	9	tubular	tubular	ADJ
american_scientific_journal-4355	48	10	epithelial	epithelial	ADJ
american_scientific_journal-4355	48	11	cells	cell	NOUN
american_scientific_journal-4355	48	12	and	and	CCONJ
american_scientific_journal-4355	48	13	possibly	possibly	ADV
american_scientific_journal-4355	48	14	tubular	tubular	VERB
american_scientific_journal-4355	48	15	epithelial	epithelial	ADJ
american_scientific_journal-4355	48	16	cells	cell	NOUN
american_scientific_journal-4355	48	17	into	into	ADP
american_scientific_journal-4355	48	18	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	48	19	.	.	PUNCT
american_scientific_journal-4355	49	1	this	this	DET
american_scientific_journal-4355	49	2	change	change	NOUN
american_scientific_journal-4355	49	3	of	of	ADP
american_scientific_journal-4355	49	4	phenotype	phenotype	NOUN
american_scientific_journal-4355	49	5	is	be	AUX
american_scientific_journal-4355	49	6	characterized	characterize	VERB
american_scientific_journal-4355	49	7	by	by	ADP
american_scientific_journal-4355	49	8	de	de	X
american_scientific_journal-4355	49	9	novo	novo	NOUN
american_scientific_journal-4355	49	10	expression	expression	NOUN
american_scientific_journal-4355	49	11	of	of	ADP
american_scientific_journal-4355	49	12	alpha	alpha	NOUN
american_scientific_journal-4355	49	13	-	-	PUNCT
american_scientific_journal-4355	49	14	smooth	smooth	ADJ
american_scientific_journal-4355	49	15	-	-	PUNCT
american_scientific_journal-4355	49	16	muscle	muscle	NOUN
american_scientific_journal-4355	49	17	actin	actin	NOUN
american_scientific_journal-4355	49	18	[	[	X
american_scientific_journal-4355	49	19	10	10	NUM
american_scientific_journal-4355	49	20	]	]	PUNCT
american_scientific_journal-4355	49	21	.	.	PUNCT
american_scientific_journal-4355	50	1	a	a	DET
american_scientific_journal-4355	50	2	specific	specific	ADJ
american_scientific_journal-4355	50	3	gene	gene	NOUN
american_scientific_journal-4355	50	4	fsp1	fsp1	NOUN
american_scientific_journal-4355	50	5	(	(	PUNCT
american_scientific_journal-4355	50	6	fibroblast	fibroblast	ADJ
american_scientific_journal-4355	50	7	-	-	PUNCT
american_scientific_journal-4355	50	8	specific	specific	ADJ
american_scientific_journal-4355	50	9	protein-1	protein-1	PROPN
american_scientific_journal-4355	50	10	)	)	PUNCT
american_scientific_journal-4355	51	1	[	[	X
american_scientific_journal-4355	51	2	11	11	NUM
american_scientific_journal-4355	51	3	]	]	PUNCT
american_scientific_journal-4355	51	4	,	,	PUNCT
american_scientific_journal-4355	51	5	has	have	AUX
american_scientific_journal-4355	51	6	been	be	AUX
american_scientific_journal-4355	51	7	cloned	clone	VERB
american_scientific_journal-4355	51	8	,	,	PUNCT
american_scientific_journal-4355	51	9	which	which	PRON
american_scientific_journal-4355	51	10	triggers	trigger	VERB
american_scientific_journal-4355	51	11	the	the	DET
american_scientific_journal-4355	51	12	transformation	transformation	NOUN
american_scientific_journal-4355	51	13	of	of	ADP
american_scientific_journal-4355	51	14	tubular	tubular	ADJ
american_scientific_journal-4355	51	15	epithelial	epithelial	ADJ
american_scientific_journal-4355	51	16	cells	cell	NOUN
american_scientific_journal-4355	51	17	into	into	ADP
american_scientific_journal-4355	51	18	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	52	1	[	[	X
american_scientific_journal-4355	52	2	12	12	NUM
american_scientific_journal-4355	52	3	]	]	PUNCT
american_scientific_journal-4355	52	4	,	,	PUNCT
american_scientific_journal-4355	52	5	in	in	ADP
american_scientific_journal-4355	52	6	response	response	NOUN
american_scientific_journal-4355	52	7	to	to	ADP
american_scientific_journal-4355	52	8	cytokines	cytokine	NOUN
american_scientific_journal-4355	52	9	,	,	PUNCT
american_scientific_journal-4355	52	10	such	such	ADJ
american_scientific_journal-4355	52	11	as	as	ADP
american_scientific_journal-4355	52	12	tgf	tgf	PROPN
american_scientific_journal-4355	52	13	-	-	PUNCT
american_scientific_journal-4355	52	14	β	β	NOUN
american_scientific_journal-4355	52	15	.	.	PUNCT
american_scientific_journal-4355	53	1	studies	study	NOUN
american_scientific_journal-4355	53	2	revealed	reveal	VERB
american_scientific_journal-4355	53	3	that	that	SCONJ
american_scientific_journal-4355	53	4	tubulointerstitial	tubulointerstitial	ADJ
american_scientific_journal-4355	53	5	disease	disease	NOUN
american_scientific_journal-4355	53	6	was	be	AUX
american_scientific_journal-4355	53	7	a	a	DET
american_scientific_journal-4355	53	8	more	more	ADV
american_scientific_journal-4355	53	9	reliable	reliable	ADJ
american_scientific_journal-4355	53	10	predictor	predictor	NOUN
american_scientific_journal-4355	53	11	of	of	ADP
american_scientific_journal-4355	53	12	functional	functional	ADJ
american_scientific_journal-4355	53	13	impairement	impairement	NOUN
american_scientific_journal-4355	53	14	than	than	SCONJ
american_scientific_journal-4355	53	15	was	be	AUX
american_scientific_journal-4355	53	16	glomerular	glomerular	ADJ
american_scientific_journal-4355	53	17	injury	injury	NOUN
american_scientific_journal-4355	53	18	in	in	ADP
american_scientific_journal-4355	53	19	a	a	DET
american_scientific_journal-4355	53	20	variety	variety	NOUN
american_scientific_journal-4355	53	21	of	of	ADP
american_scientific_journal-4355	53	22	renal	renal	ADJ
american_scientific_journal-4355	53	23	diseases	disease	NOUN
american_scientific_journal-4355	53	24	e.g.	e.g.	ADV
american_scientific_journal-4355	53	25	membranoproliferative	membranoproliferative	ADJ
american_scientific_journal-4355	53	26	glomeriulonephritis	glomeriulonephritis	NOUN
american_scientific_journal-4355	53	27	,	,	PUNCT
american_scientific_journal-4355	53	28	diabetic	diabetic	ADJ
american_scientific_journal-4355	53	29	glomeriulosclerosis	glomeriulosclerosis	NOUN
american_scientific_journal-4355	53	30	,	,	PUNCT
american_scientific_journal-4355	53	31	glomerular	glomerular	ADJ
american_scientific_journal-4355	53	32	amyloidosis	amyloidosis	NOUN
american_scientific_journal-4355	53	33	etc.[13	etc.[13	NOUN
american_scientific_journal-4355	53	34	]	]	PUNCT
american_scientific_journal-4355	53	35	.	.	PUNCT
american_scientific_journal-4355	54	1	different	different	ADJ
american_scientific_journal-4355	54	2	sources	source	NOUN
american_scientific_journal-4355	54	3	of	of	ADP
american_scientific_journal-4355	54	4	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	54	5	in	in	ADP
american_scientific_journal-4355	54	6	organ	organ	NOUN
american_scientific_journal-4355	54	7	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	54	8	.	.	PUNCT
american_scientific_journal-4355	55	1	four	four	NUM
american_scientific_journal-4355	55	2	possible	possible	ADJ
american_scientific_journal-4355	55	3	mechanisms	mechanism	NOUN
american_scientific_journal-4355	55	4	are	be	AUX
american_scientific_journal-4355	55	5	depicted	depict	VERB
american_scientific_journal-4355	55	6	.	.	PUNCT
american_scientific_journal-4355	56	1	one	one	NUM
american_scientific_journal-4355	56	2	study	study	NOUN
american_scientific_journal-4355	56	3	suggests	suggest	VERB
american_scientific_journal-4355	56	4	that	that	SCONJ
american_scientific_journal-4355	56	5	about	about	ADV
american_scientific_journal-4355	56	6	12	12	NUM
american_scientific_journal-4355	56	7	%	%	NOUN
american_scientific_journal-4355	56	8	of	of	ADP
american_scientific_journal-4355	56	9	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	56	10	are	be	AUX
american_scientific_journal-4355	56	11	from	from	ADP
american_scientific_journal-4355	56	12	bone	bone	NOUN
american_scientific_journal-4355	56	13	marrow	marrow	NOUN
american_scientific_journal-4355	56	14	,	,	PUNCT
american_scientific_journal-4355	56	15	about	about	ADV
american_scientific_journal-4355	56	16	30	30	NUM
american_scientific_journal-4355	56	17	%	%	NOUN
american_scientific_journal-4355	56	18	can	can	AUX
american_scientific_journal-4355	56	19	arise	arise	VERB
american_scientific_journal-4355	56	20	via	via	ADP
american_scientific_journal-4355	56	21	local	local	ADJ
american_scientific_journal-4355	56	22	emt	emt	NOUN
american_scientific_journal-4355	56	23	involving	involve	VERB
american_scientific_journal-4355	56	24	tubular	tubular	ADJ
american_scientific_journal-4355	56	25	epithelial	epithelial	ADJ
american_scientific_journal-4355	56	26	cells	cell	NOUN
american_scientific_journal-4355	56	27	under	under	ADP
american_scientific_journal-4355	56	28	inflammatory	inflammatory	ADJ
american_scientific_journal-4355	56	29	stress	stress	NOUN
american_scientific_journal-4355	56	30	,	,	PUNCT
american_scientific_journal-4355	56	31	and	and	CCONJ
american_scientific_journal-4355	56	32	about	about	ADV
american_scientific_journal-4355	56	33	35	35	NUM
american_scientific_journal-4355	56	34	%	%	NOUN
american_scientific_journal-4355	56	35	are	be	AUX
american_scientific_journal-4355	56	36	from	from	ADP
american_scientific_journal-4355	56	37	endmt	endmt	PROPN
american_scientific_journal-4355	57	1	[	[	X
american_scientific_journal-4355	57	2	14	14	NUM
american_scientific_journal-4355	57	3	]	]	PUNCT
american_scientific_journal-4355	57	4	.	.	PUNCT
american_scientific_journal-4355	58	1	activation	activation	NOUN
american_scientific_journal-4355	58	2	of	of	ADP
american_scientific_journal-4355	58	3	resident	resident	ADJ
american_scientific_journal-4355	58	4	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	58	5	or	or	CCONJ
american_scientific_journal-4355	58	6	other	other	ADJ
american_scientific_journal-4355	58	7	mesenchymal	mesenchymal	ADJ
american_scientific_journal-4355	58	8	cells	cell	NOUN
american_scientific_journal-4355	58	9	,	,	PUNCT
american_scientific_journal-4355	58	10	such	such	ADJ
american_scientific_journal-4355	58	11	as	as	ADP
american_scientific_journal-4355	58	12	perivascular	perivascular	ADJ
american_scientific_journal-4355	58	13	smooth	smooth	ADJ
american_scientific_journal-4355	58	14	muscle	muscle	NOUN
american_scientific_journal-4355	58	15	cells	cell	NOUN
american_scientific_journal-4355	58	16	/	/	SYM
american_scientific_journal-4355	58	17	pericytes	pericyte	NOUN
american_scientific_journal-4355	58	18	and	and	CCONJ
american_scientific_journal-4355	58	19	fibrocytes	fibrocyte	NOUN
american_scientific_journal-4355	58	20	[	[	X
american_scientific_journal-4355	58	21	15	15	NUM
american_scientific_journal-4355	58	22	]	]	PUNCT
american_scientific_journal-4355	58	23	.	.	PUNCT
american_scientific_journal-4355	59	1	the	the	DET
american_scientific_journal-4355	59	2	remaining	remain	VERB
american_scientific_journal-4355	59	3	percentage	percentage	NOUN
american_scientific_journal-4355	59	4	likely	likely	ADV
american_scientific_journal-4355	59	5	emerge	emerge	VERB
american_scientific_journal-4355	59	6	via	via	ADP
american_scientific_journal-4355	59	7	proliferation	proliferation	NOUN
american_scientific_journal-4355	59	8	of	of	ADP
american_scientific_journal-4355	59	9	the	the	DET
american_scientific_journal-4355	59	10	resident	resident	NOUN
american_scientific_journal-4355	59	11	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	59	12	and	and	CCONJ
american_scientific_journal-4355	59	13	other	other	ADJ
american_scientific_journal-4355	59	14	still	still	ADV
american_scientific_journal-4355	59	15	unidentified	unidentified	ADJ
american_scientific_journal-4355	59	16	sources	source	NOUN
american_scientific_journal-4355	59	17	.	.	PUNCT
american_scientific_journal-4355	60	1	systemic	systemic	ADJ
american_scientific_journal-4355	60	2	treatment	treatment	NOUN
american_scientific_journal-4355	60	3	of	of	ADP
american_scientific_journal-4355	60	4	mice	mouse	NOUN
american_scientific_journal-4355	60	5	with	with	ADP
american_scientific_journal-4355	60	6	renal	renal	ADJ
american_scientific_journal-4355	60	7	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	60	8	with	with	ADP
american_scientific_journal-4355	60	9	recombinant	recombinant	ADJ
american_scientific_journal-4355	60	10	human	human	NOUN
american_scientific_journal-4355	60	11	bmp-7	bmp-7	NOUN
american_scientific_journal-4355	60	12	.	.	PUNCT
american_scientific_journal-4355	61	1	the	the	DET
american_scientific_journal-4355	61	2	bone	bone	NOUN
american_scientific_journal-4355	61	3	morphogenetic	morphogenetic	ADJ
american_scientific_journal-4355	61	4	proteins	protein	NOUN
american_scientific_journal-4355	61	5	(	(	PUNCT
american_scientific_journal-4355	61	6	bmps	bmp	NOUN
american_scientific_journal-4355	61	7	)	)	PUNCT
american_scientific_journal-4355	61	8	reverses	reverse	VERB
american_scientific_journal-4355	61	9	renal	renal	ADJ
american_scientific_journal-4355	61	10	disease	disease	NOUN
american_scientific_journal-4355	61	11	due	due	ADP
american_scientific_journal-4355	61	12	to	to	ADP
american_scientific_journal-4355	61	13	severe	severe	ADJ
american_scientific_journal-4355	61	14	attenuation	attenuation	NOUN
american_scientific_journal-4355	61	15	of	of	ADP
american_scientific_journal-4355	61	16	the	the	DET
american_scientific_journal-4355	61	17	formation	formation	NOUN
american_scientific_journal-4355	61	18	of	of	ADP
american_scientific_journal-4355	61	19	emtand	emtand	ADJ
american_scientific_journal-4355	61	20	endmt	endmt	ADV
american_scientific_journal-4355	61	21	-	-	PUNCT
american_scientific_journal-4355	61	22	derived	derive	VERB
american_scientific_journal-4355	61	23	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	61	24	.	.	PUNCT
american_scientific_journal-4355	62	1	emt	emt	PROPN
american_scientific_journal-4355	62	2	is	be	AUX
american_scientific_journal-4355	62	3	a	a	DET
american_scientific_journal-4355	62	4	process	process	NOUN
american_scientific_journal-4355	62	5	usually	usually	ADV
american_scientific_journal-4355	62	6	associated	associate	VERB
american_scientific_journal-4355	62	7	with	with	ADP
american_scientific_journal-4355	62	8	an	an	DET
american_scientific_journal-4355	62	9	increase	increase	NOUN
american_scientific_journal-4355	62	10	in	in	ADP
american_scientific_journal-4355	62	11	cell	cell	NOUN
american_scientific_journal-4355	62	12	motility	motility	NOUN
american_scientific_journal-4355	62	13	and	and	CCONJ
american_scientific_journal-4355	62	14	fibrotic	fibrotic	ADJ
american_scientific_journal-4355	62	15	sequelae	sequelae	NOUN
american_scientific_journal-4355	62	16	with	with	ADP
american_scientific_journal-4355	62	17	the	the	DET
american_scientific_journal-4355	62	18	accumulation	accumulation	NOUN
american_scientific_journal-4355	62	19	of	of	ADP
american_scientific_journal-4355	62	20	a	a	DET
american_scientific_journal-4355	62	21	newly	newly	ADV
american_scientific_journal-4355	62	22	expressed	express	VERB
american_scientific_journal-4355	62	23	extracellular	extracellular	ADJ
american_scientific_journal-4355	62	24	matrix	matrix	NOUN
american_scientific_journal-4355	62	25	(	(	PUNCT
american_scientific_journal-4355	62	26	ecm	ecm	PROPN
american_scientific_journal-4355	62	27	)	)	PUNCT
american_scientific_journal-4355	62	28	.	.	PUNCT
american_scientific_journal-4355	63	1	various	various	ADJ
american_scientific_journal-4355	63	2	signalling	signal	VERB
american_scientific_journal-4355	63	3	pathways	pathway	NOUN
american_scientific_journal-4355	63	4	are	be	AUX
american_scientific_journal-4355	63	5	involved	involve	VERB
american_scientific_journal-4355	63	6	in	in	ADP
american_scientific_journal-4355	63	7	emt	emt	PROPN
american_scientific_journal-4355	63	8	.	.	PUNCT
american_scientific_journal-4355	64	1	some	some	DET
american_scientific_journal-4355	64	2	proteins	protein	NOUN
american_scientific_journal-4355	64	3	are	be	AUX
american_scientific_journal-4355	64	4	transcriptional	transcriptional	ADJ
american_scientific_journal-4355	64	5	repressors	repressor	NOUN
american_scientific_journal-4355	64	6	of	of	ADP
american_scientific_journal-4355	64	7	e	e	NOUN
american_scientific_journal-4355	64	8	-	-	NOUN
american_scientific_journal-4355	64	9	cadherin	cadherin	NOUN
american_scientific_journal-4355	64	10	and	and	CCONJ
american_scientific_journal-4355	64	11	their	their	PRON
american_scientific_journal-4355	64	12	expression	expression	NOUN
american_scientific_journal-4355	64	13	induces	induce	VERB
american_scientific_journal-4355	64	14	emt	emt	PROPN
american_scientific_journal-4355	64	15	.	.	PUNCT
american_scientific_journal-4355	65	1	recently	recently	ADV
american_scientific_journal-4355	65	2	,	,	PUNCT
american_scientific_journal-4355	65	3	activation	activation	NOUN
american_scientific_journal-4355	65	4	of	of	ADP
american_scientific_journal-4355	65	5	the	the	DET
american_scientific_journal-4355	65	6	phosphatidylinositol	phosphatidylinositol	NOUN
american_scientific_journal-4355	65	7	3	3	NUM
american_scientific_journal-4355	65	8	'	'	PART
american_scientific_journal-4355	65	9	kinase	kinase	NOUN
american_scientific_journal-4355	65	10	(	(	PUNCT
american_scientific_journal-4355	65	11	pi3k)/akt	pi3k)/akt	PROPN
american_scientific_journal-4355	65	12	axis	axis	NOUN
american_scientific_journal-4355	65	13	is	be	AUX
american_scientific_journal-4355	65	14	emerging	emerge	VERB
american_scientific_journal-4355	65	15	as	as	ADP
american_scientific_journal-4355	65	16	a	a	DET
american_scientific_journal-4355	65	17	central	central	ADJ
american_scientific_journal-4355	65	18	feature	feature	NOUN
american_scientific_journal-4355	65	19	of	of	ADP
american_scientific_journal-4355	65	20	emt	emt	PROPN
american_scientific_journal-4355	65	21	[	[	X
american_scientific_journal-4355	65	22	16	16	NUM
american_scientific_journal-4355	65	23	]	]	PUNCT
american_scientific_journal-4355	65	24	.	.	PUNCT
american_scientific_journal-4355	66	1	a	a	DET
american_scientific_journal-4355	66	2	prototypical	prototypical	ADJ
american_scientific_journal-4355	66	3	feature	feature	NOUN
american_scientific_journal-4355	66	4	of	of	ADP
american_scientific_journal-4355	66	5	epithelial	epithelial	ADJ
american_scientific_journal-4355	66	6	cells	cell	NOUN
american_scientific_journal-4355	66	7	undergoing	undergo	VERB
american_scientific_journal-4355	66	8	an	an	DET
american_scientific_journal-4355	66	9	emt‐process	emt‐process	NOUN
american_scientific_journal-4355	66	10	is	be	AUX
american_scientific_journal-4355	66	11	reduced	reduce	VERB
american_scientific_journal-4355	66	12	and	and	CCONJ
american_scientific_journal-4355	66	13	finally	finally	ADV
american_scientific_journal-4355	66	14	lost	lose	VERB
american_scientific_journal-4355	66	15	expression	expression	NOUN
american_scientific_journal-4355	66	16	of	of	ADP
american_scientific_journal-4355	66	17	the	the	DET
american_scientific_journal-4355	66	18	epithelial	epithelial	ADJ
american_scientific_journal-4355	66	19	marker	marker	NOUN
american_scientific_journal-4355	66	20	e‐cadherin	e‐cadherin	PROPN
american_scientific_journal-4355	66	21	,	,	PUNCT
american_scientific_journal-4355	66	22	a	a	DET
american_scientific_journal-4355	66	23	member	member	NOUN
american_scientific_journal-4355	66	24	of	of	ADP
american_scientific_journal-4355	66	25	the	the	DET
american_scientific_journal-4355	66	26	adherent	adherent	ADJ
american_scientific_journal-4355	66	27	junction	junction	NOUN
american_scientific_journal-4355	66	28	protein	protein	NOUN
american_scientific_journal-4355	66	29	family[17	family[17	PROPN
american_scientific_journal-4355	66	30	]	]	PUNCT
american_scientific_journal-4355	66	31	.	.	PUNCT
american_scientific_journal-4355	67	1	2	2	X
american_scientific_journal-4355	67	2	.	.	X
american_scientific_journal-4355	67	3	materials	material	NOUN
american_scientific_journal-4355	67	4	and	and	CCONJ
american_scientific_journal-4355	67	5	methods	method	NOUN
american_scientific_journal-4355	67	6	those	those	PRON
american_scientific_journal-4355	67	7	have	have	AUX
american_scientific_journal-4355	67	8	been	be	AUX
american_scientific_journal-4355	67	9	used	use	VERB
american_scientific_journal-4355	67	10	in	in	ADP
american_scientific_journal-4355	67	11	this	this	DET
american_scientific_journal-4355	67	12	abstract	abstract	NOUN
american_scientific_journal-4355	67	13	:	:	PUNCT
american_scientific_journal-4355	67	14	1	1	X
american_scientific_journal-4355	67	15	.	.	NUM
american_scientific_journal-4355	67	16	conventional	conventional	ADJ
american_scientific_journal-4355	67	17	pcr	pcr	NOUN
american_scientific_journal-4355	67	18	.	.	PUNCT
american_scientific_journal-4355	68	1	2	2	NUM
american_scientific_journal-4355	68	2	.	.	X
american_scientific_journal-4355	68	3	semi	semi	ADJ
american_scientific_journal-4355	68	4	-	-	ADJ
american_scientific_journal-4355	68	5	quantitative	quantitative	ADJ
american_scientific_journal-4355	68	6	polymerase	polymerase	NOUN
american_scientific_journal-4355	68	7	chain	chain	NOUN
american_scientific_journal-4355	68	8	reaction	reaction	NOUN
american_scientific_journal-4355	68	9	.	.	PUNCT
american_scientific_journal-4355	69	1	3	3	X
american_scientific_journal-4355	69	2	.	.	X
american_scientific_journal-4355	69	3	quantitative	quantitative	ADJ
american_scientific_journal-4355	69	4	polymerase	polymerase	NOUN
american_scientific_journal-4355	69	5	chain	chain	NOUN
american_scientific_journal-4355	69	6	reaction	reaction	NOUN
american_scientific_journal-4355	69	7	(	(	PUNCT
american_scientific_journal-4355	69	8	q	q	ADJ
american_scientific_journal-4355	69	9	-	-	ADJ
american_scientific_journal-4355	69	10	pcr	pcr	ADJ
american_scientific_journal-4355	69	11	)	)	PUNCT
american_scientific_journal-4355	69	12	.	.	PUNCT
american_scientific_journal-4355	70	1	4	4	X
american_scientific_journal-4355	70	2	.	.	X
american_scientific_journal-4355	70	3	western	western	ADJ
american_scientific_journal-4355	70	4	blot	blot	NOUN
american_scientific_journal-4355	70	5	analysis	analysis	NOUN
american_scientific_journal-4355	70	6	.	.	PUNCT
american_scientific_journal-4355	71	1	5	5	X
american_scientific_journal-4355	71	2	.	.	PUNCT
american_scientific_journal-4355	71	3	reporter	reporter	NOUN
american_scientific_journal-4355	71	4	gene	gene	NOUN
american_scientific_journal-4355	71	5	analysis	analysis	NOUN
american_scientific_journal-4355	71	6	.	.	PUNCT
american_scientific_journal-4355	72	1	6	6	X
american_scientific_journal-4355	72	2	.	.	X
american_scientific_journal-4355	72	3	statistical	statistical	ADJ
american_scientific_journal-4355	72	4	analysis	analysis	NOUN
american_scientific_journal-4355	72	5	.	.	PUNCT
american_scientific_journal-4355	73	1	these	these	DET
american_scientific_journal-4355	73	2	methods	method	NOUN
american_scientific_journal-4355	73	3	have	have	AUX
american_scientific_journal-4355	73	4	been	be	AUX
american_scientific_journal-4355	73	5	shown	show	VERB
american_scientific_journal-4355	73	6	in	in	ADP
american_scientific_journal-4355	73	7	each	each	DET
american_scientific_journal-4355	73	8	experiment	experiment	NOUN
american_scientific_journal-4355	73	9	in	in	ADP
american_scientific_journal-4355	73	10	this	this	DET
american_scientific_journal-4355	73	11	abstract	abstract	NOUN
american_scientific_journal-4355	73	12	.	.	PUNCT
american_scientific_journal-4355	74	1	2.1.transforming	2.1.transforme	VERB
american_scientific_journal-4355	74	2	growth	growth	NOUN
american_scientific_journal-4355	74	3	factor	factor	NOUN
american_scientific_journal-4355	74	4	beta	beta	PROPN
american_scientific_journal-4355	74	5	tgf	tgf	PROPN
american_scientific_journal-4355	74	6	-	-	PUNCT
american_scientific_journal-4355	74	7	β	β	NOUN
american_scientific_journal-4355	74	8	figure	figure	NOUN
american_scientific_journal-4355	74	9	1	1	NUM
american_scientific_journal-4355	74	10	:	:	PUNCT
american_scientific_journal-4355	74	11	shows	show	VERB
american_scientific_journal-4355	74	12	the	the	DET
american_scientific_journal-4355	74	13	structure	structure	NOUN
american_scientific_journal-4355	74	14	of	of	ADP
american_scientific_journal-4355	74	15	transforming	transform	VERB
american_scientific_journal-4355	74	16	growth	growth	NOUN
american_scientific_journal-4355	74	17	factor	factor	NOUN
american_scientific_journal-4355	74	18	beta	beta	NOUN
american_scientific_journal-4355	74	19	with	with	ADP
american_scientific_journal-4355	74	20	its	its	PRON
american_scientific_journal-4355	74	21	n	n	NOUN
american_scientific_journal-4355	74	22	and	and	CCONJ
american_scientific_journal-4355	74	23	c	c	NOUN
american_scientific_journal-4355	74	24	terminals	terminal	NOUN
american_scientific_journal-4355	74	25	with	with	ADP
american_scientific_journal-4355	74	26	small	small	ADJ
american_scientific_journal-4355	74	27	and	and	CCONJ
american_scientific_journal-4355	74	28	large	large	ADJ
american_scientific_journal-4355	74	29	latent	latent	NOUN
american_scientific_journal-4355	74	30	complexes	complex	NOUN
american_scientific_journal-4355	74	31	.	.	PUNCT
american_scientific_journal-4355	75	1	adapted	adapt	VERB
american_scientific_journal-4355	75	2	from	from	ADP
american_scientific_journal-4355	75	3	:	:	PUNCT
american_scientific_journal-4355	75	4	www.biochemj.org/bj/352/0601/bj3520601f01.jpg	www.biochemj.org/bj/352/0601/bj3520601f01.jpg	NOUN
american_scientific_journal-4355	75	5	,	,	PUNCT
american_scientific_journal-4355	75	6	rahmi	rahmi	ADJ
american_scientific_journal-4355	75	7	öklü	öklü	NOUN
american_scientific_journal-4355	75	8	,	,	PUNCT
american_scientific_journal-4355	75	9	and	and	CCONJ
american_scientific_journal-4355	75	10	robin	robin	PROPN
american_scientific_journal-4355	75	11	hesketh	hesketh	PROPN
american_scientific_journal-4355	75	12	2.2	2.2	NUM
american_scientific_journal-4355	75	13	.	.	PUNCT
american_scientific_journal-4355	76	1	adapted	adapt	VERB
american_scientific_journal-4355	76	2	from	from	ADP
american_scientific_journal-4355	76	3	:	:	PUNCT
american_scientific_journal-4355	76	4	researchblogs.duke.edu/jas83	researchblogs.duke.edu/jas83	NOUN
american_scientific_journal-4355	76	5	there	there	PRON
american_scientific_journal-4355	76	6	are	be	VERB
american_scientific_journal-4355	76	7	five	five	NUM
american_scientific_journal-4355	76	8	receptors	receptor	NOUN
american_scientific_journal-4355	76	9	regulating	regulate	VERB
american_scientific_journal-4355	76	10	smads	smad	NOUN
american_scientific_journal-4355	76	11	:	:	PUNCT
american_scientific_journal-4355	76	12	smad1	smad1	PROPN
american_scientific_journal-4355	76	13	,	,	PUNCT
american_scientific_journal-4355	76	14	smad2	smad2	PROPN
american_scientific_journal-4355	76	15	,	,	PUNCT
american_scientific_journal-4355	76	16	smad3	smad3	PROPN
american_scientific_journal-4355	76	17	,	,	PUNCT
american_scientific_journal-4355	76	18	smad5	smad5	PROPN
american_scientific_journal-4355	76	19	,	,	PUNCT
american_scientific_journal-4355	76	20	and	and	CCONJ
american_scientific_journal-4355	76	21	smad9	smad9	PROPN
american_scientific_journal-4355	76	22	(	(	PUNCT
american_scientific_journal-4355	76	23	sometimes	sometimes	ADV
american_scientific_journal-4355	76	24	referred	refer	VERB
american_scientific_journal-4355	76	25	to	to	ADP
american_scientific_journal-4355	76	26	as	as	ADP
american_scientific_journal-4355	76	27	smad8	smad8	NOUN
american_scientific_journal-4355	76	28	)	)	PUNCT
american_scientific_journal-4355	76	29	figure	figure	NOUN
american_scientific_journal-4355	76	30	2	2	NUM
american_scientific_journal-4355	76	31	above	above	ADV
american_scientific_journal-4355	76	32	.	.	PUNCT
american_scientific_journal-4355	77	1	there	there	PRON
american_scientific_journal-4355	77	2	are	be	VERB
american_scientific_journal-4355	77	3	essentially	essentially	ADV
american_scientific_journal-4355	77	4	two	two	NUM
american_scientific_journal-4355	77	5	intracellular	intracellular	ADJ
american_scientific_journal-4355	77	6	pathways	pathway	NOUN
american_scientific_journal-4355	77	7	involving	involve	VERB
american_scientific_journal-4355	77	8	these	these	DET
american_scientific_journal-4355	77	9	r	r	NOUN
american_scientific_journal-4355	77	10	-	-	PUNCT
american_scientific_journal-4355	77	11	smads	smad	NOUN
american_scientific_journal-4355	77	12	.	.	PUNCT
american_scientific_journal-4355	78	1	tgf	tgf	PROPN
american_scientific_journal-4355	78	2	beta	beta	PROPN
american_scientific_journal-4355	78	3	's	's	PART
american_scientific_journal-4355	78	4	,	,	PUNCT
american_scientific_journal-4355	78	5	activins	activin	NOUN
american_scientific_journal-4355	78	6	,	,	PUNCT
american_scientific_journal-4355	78	7	nodals	nodal	NOUN
american_scientific_journal-4355	78	8	and	and	CCONJ
american_scientific_journal-4355	78	9	some	some	DET
american_scientific_journal-4355	78	10	gdfs	gdfs	NOUN
american_scientific_journal-4355	78	11	(	(	PUNCT
american_scientific_journal-4355	78	12	growth	growth	NOUN
american_scientific_journal-4355	78	13	and	and	CCONJ
american_scientific_journal-4355	78	14	differentiation	differentiation	NOUN
american_scientific_journal-4355	78	15	factors	factor	NOUN
american_scientific_journal-4355	78	16	(	(	PUNCT
american_scientific_journal-4355	78	17	gdfs	gdfs	NOUN
american_scientific_journal-4355	78	18	)	)	PUNCT
american_scientific_journal-4355	78	19	are	be	AUX
american_scientific_journal-4355	78	20	mediated	mediate	VERB
american_scientific_journal-4355	78	21	by	by	ADP
american_scientific_journal-4355	78	22	smad2	smad2	PROPN
american_scientific_journal-4355	78	23	and	and	CCONJ
american_scientific_journal-4355	78	24	smad3	smad3	NOUN
american_scientific_journal-4355	78	25	,	,	PUNCT
american_scientific_journal-4355	78	26	while	while	SCONJ
american_scientific_journal-4355	78	27	bmps	bmp	NOUN
american_scientific_journal-4355	78	28	(	(	PUNCT
american_scientific_journal-4355	78	29	bone	bone	NOUN
american_scientific_journal-4355	78	30	morphogenetic	morphogenetic	ADJ
american_scientific_journal-4355	78	31	proteins	protein	NOUN
american_scientific_journal-4355	78	32	)	)	PUNCT
american_scientific_journal-4355	78	33	,	,	PUNCT
american_scientific_journal-4355	78	34	amh(anti	amh(anti	ADJ
american_scientific_journal-4355	78	35	-	-	ADJ
american_scientific_journal-4355	78	36	mullerian	mullerian	ADJ
american_scientific_journal-4355	78	37	hormone	hormone	NOUN
american_scientific_journal-4355	78	38	)	)	PUNCT
american_scientific_journal-4355	78	39	and	and	CCONJ
american_scientific_journal-4355	78	40	a	a	DET
american_scientific_journal-4355	78	41	few	few	ADJ
american_scientific_journal-4355	78	42	gdfs	gdfs	NOUN
american_scientific_journal-4355	78	43	are	be	AUX
american_scientific_journal-4355	78	44	mediated	mediate	VERB
american_scientific_journal-4355	78	45	by	by	ADP
american_scientific_journal-4355	78	46	smad1	smad1	PROPN
american_scientific_journal-4355	78	47	,	,	PUNCT
american_scientific_journal-4355	78	48	smad5	smad5	PROPN
american_scientific_journal-4355	78	49	and	and	CCONJ
american_scientific_journal-4355	78	50	smad9	smad9	PROPN
american_scientific_journal-4355	78	51	.	.	PUNCT
american_scientific_journal-4355	79	1	binding	bind	VERB
american_scientific_journal-4355	79	2	of	of	ADP
american_scientific_journal-4355	79	3	transforming	transform	VERB
american_scientific_journal-4355	79	4	growth	growth	NOUN
american_scientific_journal-4355	79	5	factor	factor	NOUN
american_scientific_journal-4355	79	6	beta	beta	NOUN
american_scientific_journal-4355	79	7	(	(	PUNCT
american_scientific_journal-4355	79	8	tgf	tgf	PROPN
american_scientific_journal-4355	79	9	-	-	PUNCT
american_scientific_journal-4355	79	10	β	β	NOUN
american_scientific_journal-4355	79	11	)	)	PUNCT
american_scientific_journal-4355	79	12	to	to	ADP
american_scientific_journal-4355	79	13	its	its	PRON
american_scientific_journal-4355	79	14	cell	cell	NOUN
american_scientific_journal-4355	79	15	surface	surface	NOUN
american_scientific_journal-4355	79	16	receptor	receptor	NOUN
american_scientific_journal-4355	79	17	type	type	NOUN
american_scientific_journal-4355	79	18	ii	ii	PROPN
american_scientific_journal-4355	79	19	leads	lead	VERB
american_scientific_journal-4355	79	20	to	to	ADP
american_scientific_journal-4355	79	21	the	the	DET
american_scientific_journal-4355	79	22	phosphorylation	phosphorylation	NOUN
american_scientific_journal-4355	79	23	of	of	ADP
american_scientific_journal-4355	79	24	the	the	DET
american_scientific_journal-4355	79	25	type	type	NOUN
american_scientific_journal-4355	79	26	i	i	PRON
american_scientific_journal-4355	79	27	receptor	receptor	VERB
american_scientific_journal-4355	79	28	by	by	ADP
american_scientific_journal-4355	79	29	type	type	NOUN
american_scientific_journal-4355	79	30	ii	ii	PROPN
american_scientific_journal-4355	79	31	.	.	PUNCT
american_scientific_journal-4355	80	1	the	the	DET
american_scientific_journal-4355	80	2	type	type	NOUN
american_scientific_journal-4355	80	3	i	i	PRON
american_scientific_journal-4355	80	4	receptor	receptor	NOUN
american_scientific_journal-4355	80	5	is	be	AUX
american_scientific_journal-4355	80	6	then	then	ADV
american_scientific_journal-4355	80	7	able	able	ADJ
american_scientific_journal-4355	80	8	to	to	PART
american_scientific_journal-4355	80	9	phosphorylate	phosphorylate	VERB
american_scientific_journal-4355	80	10	and	and	CCONJ
american_scientific_journal-4355	80	11	activate	activate	VERB
american_scientific_journal-4355	80	12	the	the	DET
american_scientific_journal-4355	80	13	smad2	smad2	PROPN
american_scientific_journal-4355	80	14	protein	protein	NOUN
american_scientific_journal-4355	80	15	.	.	PUNCT
american_scientific_journal-4355	81	1	smad2	smad2	PROPN
american_scientific_journal-4355	81	2	,	,	PUNCT
american_scientific_journal-4355	81	3	with	with	ADP
american_scientific_journal-4355	81	4	smad4	smad4	NOUN
american_scientific_journal-4355	81	5	,	,	PUNCT
american_scientific_journal-4355	81	6	is	be	AUX
american_scientific_journal-4355	81	7	translocated	translocate	VERB
american_scientific_journal-4355	81	8	to	to	ADP
american_scientific_journal-4355	81	9	the	the	DET
american_scientific_journal-4355	81	10	nucleus	nucleus	NOUN
american_scientific_journal-4355	81	11	where	where	SCONJ
american_scientific_journal-4355	81	12	the	the	DET
american_scientific_journal-4355	81	13	activated	activate	VERB
american_scientific_journal-4355	81	14	smad	smad	PROPN
american_scientific_journal-4355	81	15	complex	complex	PROPN
american_scientific_journal-4355	81	16	recruits	recruit	VERB
american_scientific_journal-4355	81	17	other	other	ADJ
american_scientific_journal-4355	81	18	biological	biological	ADJ
american_scientific_journal-4355	81	19	effects	effect	NOUN
american_scientific_journal-4355	81	20	of	of	ADP
american_scientific_journal-4355	81	21	tgf	tgf	PROPN
american_scientific_journal-4355	81	22	-	-	PUNCT
american_scientific_journal-4355	81	23	b	b	PROPN
american_scientific_journal-4355	81	24	,	,	PUNCT
american_scientific_journal-4355	81	25	the	the	DET
american_scientific_journal-4355	81	26	above	above	ADJ
american_scientific_journal-4355	81	27	explained	explain	VERB
american_scientific_journal-4355	81	28	pathway	pathway	NOUN
american_scientific_journal-4355	81	29	called	call	VERB
american_scientific_journal-4355	81	30	the	the	DET
american_scientific_journal-4355	81	31	classical	classical	ADJ
american_scientific_journal-4355	81	32	signalling	signal	VERB
american_scientific_journal-4355	81	33	pathway	pathway	NOUN
american_scientific_journal-4355	81	34	of	of	ADP
american_scientific_journal-4355	81	35	tgf	tgf	PROPN
american_scientific_journal-4355	81	36	-	-	PUNCT
american_scientific_journal-4355	81	37	β	β	PROPN
american_scientific_journal-4355	81	38	(	(	PUNCT
american_scientific_journal-4355	81	39	figure	figure	NOUN
american_scientific_journal-4355	81	40	4	4	NUM
american_scientific_journal-4355	81	41	)	)	PUNCT
american_scientific_journal-4355	81	42	.	.	PUNCT
american_scientific_journal-4355	82	1	there	there	PRON
american_scientific_journal-4355	82	2	are	be	VERB
american_scientific_journal-4355	82	3	also	also	ADV
american_scientific_journal-4355	82	4	smad	smad	ADJ
american_scientific_journal-4355	82	5	-	-	ADJ
american_scientific_journal-4355	82	6	independent	independent	ADJ
american_scientific_journal-4355	82	7	pathways	pathway	NOUN
american_scientific_journal-4355	82	8	activated	activate	VERB
american_scientific_journal-4355	82	9	by	by	ADP
american_scientific_journal-4355	82	10	tgf	tgf	PROPN
american_scientific_journal-4355	82	11	binding	bind	VERB
american_scientific_journal-4355	82	12	its	its	PRON
american_scientific_journal-4355	82	13	receptors	receptor	NOUN
american_scientific_journal-4355	82	14	as	as	ADP
american_scientific_journal-4355	82	15	rho	rho	ADJ
american_scientific_journal-4355	82	16	,	,	PUNCT
american_scientific_journal-4355	82	17	mapk	mapk	NOUN
american_scientific_journal-4355	82	18	,	,	PUNCT
american_scientific_journal-4355	82	19	pkc	pkc	PROPN
american_scientific_journal-4355	82	20	,	,	PUNCT
american_scientific_journal-4355	82	21	cross	cross	ADJ
american_scientific_journal-4355	82	22	-	-	ADJ
american_scientific_journal-4355	82	23	talk	talk	ADJ
american_scientific_journal-4355	82	24	tgf	tgf	PROPN
american_scientific_journal-4355	82	25	-	-	PUNCT
american_scientific_journal-4355	82	26	β	β	PROPN
american_scientific_journal-4355	82	27	signalling	signalling	NOUN
american_scientific_journal-4355	82	28	and	and	CCONJ
american_scientific_journal-4355	82	29	wint	wint	NOUN
american_scientific_journal-4355	82	30	pathways	pathway	NOUN
american_scientific_journal-4355	82	31	.	.	PUNCT
american_scientific_journal-4355	83	1	figure	figure	VERB
american_scientific_journal-4355	83	2	2	2	NUM
american_scientific_journal-4355	83	3	:	:	PUNCT
american_scientific_journal-4355	83	4	signalling	signal	VERB
american_scientific_journal-4355	83	5	pathways	pathway	NOUN
american_scientific_journal-4355	83	6	of	of	ADP
american_scientific_journal-4355	83	7	tgf	tgf	PROPN
american_scientific_journal-4355	83	8	-	-	PUNCT
american_scientific_journal-4355	83	9	β	β	NOUN
american_scientific_journal-4355	83	10	.	.	PUNCT
american_scientific_journal-4355	84	1	the	the	DET
american_scientific_journal-4355	84	2	classical	classical	ADJ
american_scientific_journal-4355	84	3	signalling	signal	VERB
american_scientific_journal-4355	84	4	pathway	pathway	NOUN
american_scientific_journal-4355	84	5	2.3	2.3	NUM
american_scientific_journal-4355	84	6	.	.	PUNCT
american_scientific_journal-4355	85	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	85	2	(	(	PUNCT
american_scientific_journal-4355	85	3	tgf	tgf	PROPN
american_scientific_journal-4355	85	4	-	-	PUNCT
american_scientific_journal-4355	85	5	β	β	PROPN
american_scientific_journal-4355	85	6	riii	riii	PROPN
american_scientific_journal-4355	85	7	)	)	PUNCT
american_scientific_journal-4355	85	8	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	85	9	is	be	AUX
american_scientific_journal-4355	85	10	transforming	transform	VERB
american_scientific_journal-4355	85	11	growth	growth	NOUN
american_scientific_journal-4355	85	12	factor	factor	NOUN
american_scientific_journal-4355	85	13	beta	beta	NOUN
american_scientific_journal-4355	85	14	receptor	receptor	NOUN
american_scientific_journal-4355	85	15	iii	iii	X
american_scientific_journal-4355	85	16	(	(	PUNCT
american_scientific_journal-4355	85	17	tgfbr3	tgfbr3	PROPN
american_scientific_journal-4355	85	18	)	)	PUNCT
american_scientific_journal-4355	85	19	,	,	PUNCT
american_scientific_journal-4355	85	20	(	(	PUNCT
american_scientific_journal-4355	85	21	figure-3	figure-3	NUM
american_scientific_journal-4355	85	22	)	)	PUNCT
american_scientific_journal-4355	85	23	and	and	CCONJ
american_scientific_journal-4355	85	24	identified	identify	VERB
american_scientific_journal-4355	85	25	as	as	ADP
american_scientific_journal-4355	85	26	an	an	DET
american_scientific_journal-4355	85	27	accessory	accessory	ADJ
american_scientific_journal-4355	85	28	receptor	receptor	NOUN
american_scientific_journal-4355	85	29	for	for	ADP
american_scientific_journal-4355	85	30	the	the	DET
american_scientific_journal-4355	85	31	tgfβs	tgfβs	NOUN
american_scientific_journal-4355	85	32	is	be	AUX
american_scientific_journal-4355	85	33	a	a	DET
american_scientific_journal-4355	85	34	cell	cell	NOUN
american_scientific_journal-4355	85	35	-	-	PUNCT
american_scientific_journal-4355	85	36	surface	surface	NOUN
american_scientific_journal-4355	85	37	chondroitin	chondroitin	NOUN
american_scientific_journal-4355	85	38	sulfate	sulfate	NOUN
american_scientific_journal-4355	85	39	/	/	SYM
american_scientific_journal-4355	85	40	heparan	heparan	ADJ
american_scientific_journal-4355	85	41	sulfate	sulfate	NOUN
american_scientific_journal-4355	85	42	proteoglycan	proteoglycan	ADJ
american_scientific_journal-4355	85	43	,	,	PUNCT
american_scientific_journal-4355	85	44	its	its	PRON
american_scientific_journal-4355	85	45	molecular	molecular	ADJ
american_scientific_journal-4355	85	46	weight	weight	NOUN
american_scientific_journal-4355	85	47	is	be	AUX
american_scientific_journal-4355	85	48	about	about	ADP
american_scientific_journal-4355	85	49	>	>	SYM
american_scientific_journal-4355	85	50	300	300	NUM
american_scientific_journal-4355	85	51	kda.(figure	kda.(figure	NOUN
american_scientific_journal-4355	85	52	3,10	3,10	NUM
american_scientific_journal-4355	85	53	)	)	PUNCT
american_scientific_journal-4355	85	54	.	.	PUNCT
american_scientific_journal-4355	86	1	it	it	PRON
american_scientific_journal-4355	86	2	is	be	AUX
american_scientific_journal-4355	86	3	a	a	DET
american_scientific_journal-4355	86	4	transmembrane	transmembrane	NOUN
american_scientific_journal-4355	86	5	proteoglycan	proteoglycan	NOUN
american_scientific_journal-4355	86	6	with	with	ADP
american_scientific_journal-4355	86	7	a	a	DET
american_scientific_journal-4355	86	8	large	large	ADJ
american_scientific_journal-4355	86	9	extracellular	extracellular	ADJ
american_scientific_journal-4355	86	10	domain	domain	NOUN
american_scientific_journal-4355	86	11	that	that	PRON
american_scientific_journal-4355	86	12	binds	bind	VERB
american_scientific_journal-4355	86	13	tgf	tgf	PROPN
american_scientific_journal-4355	86	14	-	-	PUNCT
american_scientific_journal-4355	86	15	β	β	PROPN
american_scientific_journal-4355	86	16	with	with	ADP
american_scientific_journal-4355	86	17	high	high	ADJ
american_scientific_journal-4355	86	18	affinity	affinity	NOUN
american_scientific_journal-4355	86	19	but	but	CCONJ
american_scientific_journal-4355	86	20	lacks	lack	VERB
american_scientific_journal-4355	86	21	a	a	DET
american_scientific_journal-4355	86	22	cytoplasmic	cytoplasmic	ADJ
american_scientific_journal-4355	86	23	signaling	signal	VERB
american_scientific_journal-4355	86	24	domain	domain	NOUN
american_scientific_journal-4355	86	25	[	[	X
american_scientific_journal-4355	86	26	18	18	NUM
american_scientific_journal-4355	86	27	]	]	PUNCT
american_scientific_journal-4355	86	28	.	.	PUNCT
american_scientific_journal-4355	87	1	it	it	PRON
american_scientific_journal-4355	87	2	is	be	AUX
american_scientific_journal-4355	87	3	formed	form	VERB
american_scientific_journal-4355	87	4	from	from	ADP
american_scientific_journal-4355	87	5	heparin	heparin	ADJ
american_scientific_journal-4355	87	6	and	and	CCONJ
american_scientific_journal-4355	87	7	chondroitin	chondroitin	NOUN
american_scientific_journal-4355	87	8	sulphate	sulphate	NOUN
american_scientific_journal-4355	87	9	,	,	PUNCT
american_scientific_journal-4355	87	10	core	core	NOUN
american_scientific_journal-4355	87	11	protein	protein	NOUN
american_scientific_journal-4355	87	12	,	,	PUNCT
american_scientific_journal-4355	87	13	ectodomain	ectodomain	VERB
american_scientific_journal-4355	87	14	part	part	NOUN
american_scientific_journal-4355	87	15	,	,	PUNCT
american_scientific_journal-4355	87	16	with	with	ADP
american_scientific_journal-4355	87	17	its	its	PRON
american_scientific_journal-4355	87	18	n	n	NOUN
american_scientific_journal-4355	87	19	and	and	CCONJ
american_scientific_journal-4355	87	20	c	c	NOUN
american_scientific_journal-4355	87	21	terminals	terminal	NOUN
american_scientific_journal-4355	87	22	binding	bind	VERB
american_scientific_journal-4355	87	23	to	to	ADP
american_scientific_journal-4355	87	24	ecm	ecm	PROPN
american_scientific_journal-4355	87	25	and	and	CCONJ
american_scientific_journal-4355	87	26	cytoskeleton	cytoskeleton	PROPN
american_scientific_journal-4355	87	27	(	(	PUNCT
american_scientific_journal-4355	87	28	figure	figure	NOUN
american_scientific_journal-4355	87	29	3	3	NUM
american_scientific_journal-4355	87	30	)	)	PUNCT
american_scientific_journal-4355	87	31	.	.	PUNCT
american_scientific_journal-4355	88	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	88	2	binds	bind	VERB
american_scientific_journal-4355	88	3	to	to	ADP
american_scientific_journal-4355	88	4	various	various	ADJ
american_scientific_journal-4355	88	5	members	member	NOUN
american_scientific_journal-4355	88	6	of	of	ADP
american_scientific_journal-4355	88	7	the	the	DET
american_scientific_journal-4355	88	8	tgf	tgf	NOUN
american_scientific_journal-4355	88	9	-	-	PUNCT
american_scientific_journal-4355	88	10	beta	beta	NOUN
american_scientific_journal-4355	88	11	of	of	ADP
american_scientific_journal-4355	88	12	ligands	ligand	NOUN
american_scientific_journal-4355	88	13	by	by	ADP
american_scientific_journal-4355	88	14	its	its	PRON
american_scientific_journal-4355	88	15	superfamily	superfamily	ADJ
american_scientific_journal-4355	88	16	core	core	NOUN
american_scientific_journal-4355	88	17	protein	protein	NOUN
american_scientific_journal-4355	88	18	,	,	PUNCT
american_scientific_journal-4355	88	19	and	and	CCONJ
american_scientific_journal-4355	88	20	bfgf	bfgf	NOUN
american_scientific_journal-4355	88	21	(	(	PUNCT
american_scientific_journal-4355	88	22	basic	basic	ADJ
american_scientific_journal-4355	88	23	fibroblast	fibroblast	ADJ
american_scientific_journal-4355	88	24	growth	growth	NOUN
american_scientific_journal-4355	88	25	factor	factor	NOUN
american_scientific_journal-4355	88	26	)	)	PUNCT
american_scientific_journal-4355	88	27	,	,	PUNCT
american_scientific_journal-4355	88	28	via	via	ADP
american_scientific_journal-4355	88	29	its	its	PRON
american_scientific_journal-4355	88	30	heparan	heparan	ADJ
american_scientific_journal-4355	88	31	sulfate	sulfate	NOUN
american_scientific_journal-4355	88	32	chains	chain	NOUN
american_scientific_journal-4355	88	33	.	.	PUNCT
american_scientific_journal-4355	89	1	it	it	PRON
american_scientific_journal-4355	89	2	is	be	AUX
american_scientific_journal-4355	89	3	not	not	PART
american_scientific_journal-4355	89	4	involved	involve	VERB
american_scientific_journal-4355	89	5	directly	directly	ADV
american_scientific_journal-4355	89	6	in	in	ADP
american_scientific_journal-4355	89	7	tgf	tgf	PROPN
american_scientific_journal-4355	89	8	-	-	PUNCT
american_scientific_journal-4355	89	9	beta	beta	NOUN
american_scientific_journal-4355	89	10	signal	signal	NOUN
american_scientific_journal-4355	89	11	transduction	transduction	NOUN
american_scientific_journal-4355	89	12	but	but	CCONJ
american_scientific_journal-4355	89	13	by	by	ADP
american_scientific_journal-4355	89	14	binding	bind	VERB
american_scientific_journal-4355	89	15	to	to	ADP
american_scientific_journal-4355	89	16	different	different	ADJ
american_scientific_journal-4355	89	17	member	member	NOUN
american_scientific_journal-4355	89	18	of	of	ADP
american_scientific_journal-4355	89	19	the	the	DET
american_scientific_journal-4355	89	20	tgf	tgf	NOUN
american_scientific_journal-4355	89	21	-	-	PUNCT
american_scientific_journal-4355	89	22	beta	beta	NOUN
american_scientific_journal-4355	89	23	superfamily	superfamily	NOUN
american_scientific_journal-4355	89	24	at	at	ADP
american_scientific_journal-4355	89	25	the	the	DET
american_scientific_journal-4355	89	26	cell	cell	NOUN
american_scientific_journal-4355	89	27	surface	surface	NOUN
american_scientific_journal-4355	89	28	,	,	PUNCT
american_scientific_journal-4355	89	29	it	it	PRON
american_scientific_journal-4355	89	30	acts	act	VERB
american_scientific_journal-4355	89	31	as	as	ADP
american_scientific_journal-4355	89	32	a	a	DET
american_scientific_journal-4355	89	33	reservoir	reservoir	NOUN
american_scientific_journal-4355	89	34	of	of	ADP
american_scientific_journal-4355	89	35	ligand	ligand	NOUN
american_scientific_journal-4355	89	36	for	for	ADP
american_scientific_journal-4355	89	37	tgf	tgf	PROPN
american_scientific_journal-4355	89	38	-	-	PUNCT
american_scientific_journal-4355	89	39	beta	beta	NOUN
american_scientific_journal-4355	89	40	receptors[19	receptors[19	NOUN
american_scientific_journal-4355	89	41	]	]	PUNCT
american_scientific_journal-4355	89	42	.	.	PUNCT
american_scientific_journal-4355	90	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	90	2	is	be	AUX
american_scientific_journal-4355	90	3	known	know	VERB
american_scientific_journal-4355	90	4	to	to	PART
american_scientific_journal-4355	90	5	be	be	AUX
american_scientific_journal-4355	90	6	a	a	DET
american_scientific_journal-4355	90	7	proteoglycan	proteoglycan	ADJ
american_scientific_journal-4355	90	8	tgf	tgf	PROPN
american_scientific_journal-4355	90	9	-	-	PUNCT
american_scientific_journal-4355	90	10	β	β	X
american_scientific_journal-4355	90	11	co	co	NOUN
american_scientific_journal-4355	90	12	-	-	NOUN
american_scientific_journal-4355	90	13	receptor	receptor	NOUN
american_scientific_journal-4355	90	14	for	for	ADP
american_scientific_journal-4355	90	15	tgf	tgf	PROPN
american_scientific_journal-4355	90	16	-	-	PUNCT
american_scientific_journal-4355	90	17	β	β	NOUN
american_scientific_journal-4355	90	18	ligands	ligand	NOUN
american_scientific_journal-4355	90	19	,	,	PUNCT
american_scientific_journal-4355	90	20	it	it	PRON
american_scientific_journal-4355	90	21	is	be	AUX
american_scientific_journal-4355	90	22	undergoes	undergoe	NOUN
american_scientific_journal-4355	90	23	ectodomaine	ectodomaine	NOUN
american_scientific_journal-4355	90	24	cleavage	cleavage	NOUN
american_scientific_journal-4355	90	25	and	and	CCONJ
american_scientific_journal-4355	90	26	production	production	NOUN
american_scientific_journal-4355	90	27	of	of	ADP
american_scientific_journal-4355	90	28	a	a	DET
american_scientific_journal-4355	90	29	soluble	soluble	ADJ
american_scientific_journal-4355	90	30	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	90	31	fragment	fragment	NOUN
american_scientific_journal-4355	90	32	which	which	PRON
american_scientific_journal-4355	90	33	is	be	AUX
american_scientific_journal-4355	90	34	stable	stable	ADJ
american_scientific_journal-4355	90	35	in	in	ADP
american_scientific_journal-4355	90	36	presence	presence	NOUN
american_scientific_journal-4355	90	37	of	of	ADP
american_scientific_journal-4355	90	38	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	90	39	and	and	CCONJ
american_scientific_journal-4355	90	40	if	if	SCONJ
american_scientific_journal-4355	90	41	we	we	PRON
american_scientific_journal-4355	90	42	treat	treat	VERB
american_scientific_journal-4355	90	43	the	the	DET
american_scientific_journal-4355	90	44	cells	cell	NOUN
american_scientific_journal-4355	90	45	that	that	PRON
american_scientific_journal-4355	90	46	express	express	VERB
american_scientific_journal-4355	90	47	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	90	48	with	with	ADP
american_scientific_journal-4355	90	49	inhibitors	inhibitor	NOUN
american_scientific_journal-4355	90	50	of	of	ADP
american_scientific_journal-4355	90	51	intramembrane	intramembrane	ADJ
american_scientific_journal-4355	90	52	protease	protease	NOUN
american_scientific_journal-4355	90	53	γ	γ	NOUN
american_scientific_journal-4355	90	54	-	-	PUNCT
american_scientific_journal-4355	90	55	secretase	secretase	NOUN
american_scientific_journal-4355	90	56	,	,	PUNCT
american_scientific_journal-4355	90	57	it	it	PRON
american_scientific_journal-4355	90	58	stabilizes	stabilize	VERB
american_scientific_journal-4355	90	59	this	this	DET
american_scientific_journal-4355	90	60	fragment	fragment	NOUN
american_scientific_journal-4355	90	61	means	mean	VERB
american_scientific_journal-4355	90	62	that	that	SCONJ
american_scientific_journal-4355	90	63	it	it	PRON
american_scientific_journal-4355	90	64	is	be	AUX
american_scientific_journal-4355	90	65	a	a	DET
american_scientific_journal-4355	90	66	γ	γ	NOUN
american_scientific_journal-4355	90	67	-	-	ADJ
american_scientific_journal-4355	90	68	secretase	secretase	ADJ
american_scientific_journal-4355	90	69	substrate	substrate	NOUN
american_scientific_journal-4355	90	70	,	,	PUNCT
american_scientific_journal-4355	90	71	all	all	PRON
american_scientific_journal-4355	90	72	of	of	ADP
american_scientific_journal-4355	90	73	these	these	PRON
american_scientific_journal-4355	90	74	are	be	AUX
american_scientific_journal-4355	90	75	independent	independent	ADJ
american_scientific_journal-4355	90	76	of	of	ADP
american_scientific_journal-4355	90	77	the	the	DET
american_scientific_journal-4355	90	78	effects	effect	NOUN
american_scientific_journal-4355	90	79	of	of	ADP
american_scientific_journal-4355	90	80	tgf	tgf	PROPN
american_scientific_journal-4355	90	81	-	-	PUNCT
american_scientific_journal-4355	90	82	β	β	NOUN
american_scientific_journal-4355	90	83	.	.	PUNCT
american_scientific_journal-4355	91	1	so	so	ADV
american_scientific_journal-4355	91	2	transmembrane	transmembrane	ADJ
american_scientific_journal-4355	91	3	-	-	PUNCT
american_scientific_journal-4355	91	4	cytoplasmic	cytoplasmic	ADJ
american_scientific_journal-4355	91	5	fragment	fragment	NOUN
american_scientific_journal-4355	91	6	will	will	AUX
american_scientific_journal-4355	91	7	be	be	AUX
american_scientific_journal-4355	91	8	stable	stable	ADJ
american_scientific_journal-4355	91	9	after	after	ADP
american_scientific_journal-4355	91	10	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	91	11	cleavage	cleavage	NOUN
american_scientific_journal-4355	91	12	,	,	PUNCT
american_scientific_journal-4355	91	13	this	this	PRON
american_scientific_journal-4355	91	14	gives	give	VERB
american_scientific_journal-4355	91	15	rise	rise	NOUN
american_scientific_journal-4355	91	16	to	to	ADP
american_scientific_journal-4355	91	17	an	an	DET
american_scientific_journal-4355	91	18	implication	implication	NOUN
american_scientific_journal-4355	91	19	for	for	ADP
american_scientific_journal-4355	91	20	tgf	tgf	PROPN
american_scientific_journal-4355	91	21	-	-	PUNCT
american_scientific_journal-4355	91	22	β	β	NOUN
american_scientific_journal-4355	91	23	effects	effect	NOUN
american_scientific_journal-4355	91	24	and	and	CCONJ
american_scientific_journal-4355	91	25	response	response	NOUN
american_scientific_journal-4355	91	26	.	.	PUNCT
american_scientific_journal-4355	92	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	92	2	is	be	AUX
american_scientific_journal-4355	92	3	important	important	ADJ
american_scientific_journal-4355	92	4	regulator	regulator	NOUN
american_scientific_journal-4355	92	5	of	of	ADP
american_scientific_journal-4355	92	6	development	development	NOUN
american_scientific_journal-4355	92	7	,	,	PUNCT
american_scientific_journal-4355	92	8	differentiation	differentiation	NOUN
american_scientific_journal-4355	92	9	and	and	CCONJ
american_scientific_journal-4355	92	10	tumor	tumor	NOUN
american_scientific_journal-4355	92	11	metastasis	metastasis	NOUN
american_scientific_journal-4355	92	12	,	,	PUNCT
american_scientific_journal-4355	92	13	it	it	PRON
american_scientific_journal-4355	92	14	modulates	modulate	VERB
american_scientific_journal-4355	92	15	some	some	DET
american_scientific_journal-4355	92	16	effects	effect	NOUN
american_scientific_journal-4355	92	17	of	of	ADP
american_scientific_journal-4355	92	18	tgf	tgf	PROPN
american_scientific_journal-4355	92	19	-	-	PUNCT
american_scientific_journal-4355	92	20	β	β	PROPN
american_scientific_journal-4355	92	21	,	,	PUNCT
american_scientific_journal-4355	92	22	it	it	PRON
american_scientific_journal-4355	92	23	binds	bind	VERB
american_scientific_journal-4355	92	24	the	the	DET
american_scientific_journal-4355	92	25	three	three	NUM
american_scientific_journal-4355	92	26	tgf	tgf	PROPN
american_scientific_journal-4355	92	27	-	-	PUNCT
american_scientific_journal-4355	92	28	β	β	NOUN
american_scientific_journal-4355	92	29	isoforms	isoform	NOUN
american_scientific_journal-4355	92	30	through	through	ADP
american_scientific_journal-4355	92	31	two	two	NUM
american_scientific_journal-4355	92	32	binding	bind	VERB
american_scientific_journal-4355	92	33	sites	site	NOUN
american_scientific_journal-4355	92	34	on	on	ADP
american_scientific_journal-4355	92	35	the	the	DET
american_scientific_journal-4355	92	36	core	core	NOUN
american_scientific_journal-4355	92	37	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	92	38	also	also	ADV
american_scientific_journal-4355	92	39	enhances	enhance	VERB
american_scientific_journal-4355	92	40	tgf	tgf	PROPN
american_scientific_journal-4355	92	41	-	-	PUNCT
american_scientific_journal-4355	92	42	β	β	NOUN
american_scientific_journal-4355	92	43	signalling	signal	VERB
american_scientific_journal-4355	92	44	by	by	ADP
american_scientific_journal-4355	92	45	increasing	increase	VERB
american_scientific_journal-4355	92	46	affinity	affinity	NOUN
american_scientific_journal-4355	92	47	of	of	ADP
american_scientific_journal-4355	92	48	the	the	DET
american_scientific_journal-4355	92	49	ligand	ligand	ADJ
american_scientific_journal-4355	92	50	fortgf	fortgf	NOUN
american_scientific_journal-4355	92	51	-	-	PUNCT
american_scientific_journal-4355	92	52	βii	βii	NOUN
american_scientific_journal-4355	92	53	,	,	PUNCT
american_scientific_journal-4355	92	54	on	on	ADP
american_scientific_journal-4355	92	55	the	the	DET
american_scientific_journal-4355	92	56	other	other	ADJ
american_scientific_journal-4355	92	57	hand	hand	NOUN
american_scientific_journal-4355	92	58	,	,	PUNCT
american_scientific_journal-4355	92	59	it	it	PRON
american_scientific_journal-4355	92	60	has	have	VERB
american_scientific_journal-4355	92	61	also	also	ADV
american_scientific_journal-4355	92	62	an	an	DET
american_scientific_journal-4355	92	63	inhibitory	inhibitory	ADJ
american_scientific_journal-4355	92	64	function	function	NOUN
american_scientific_journal-4355	92	65	by	by	ADP
american_scientific_journal-4355	92	66	binding	bind	VERB
american_scientific_journal-4355	92	67	to	to	ADP
american_scientific_journal-4355	92	68	tgf	tgf	PROPN
american_scientific_journal-4355	92	69	-	-	PUNCT
american_scientific_journal-4355	92	70	β	β	NOUN
american_scientific_journal-4355	92	71	members	member	NOUN
american_scientific_journal-4355	92	72	.	.	PUNCT
american_scientific_journal-4355	93	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	93	2	undergoes	undergo	VERB
american_scientific_journal-4355	93	3	ligand	ligand	NOUN
american_scientific_journal-4355	93	4	-	-	PUNCT
american_scientific_journal-4355	93	5	independent	independent	ADJ
american_scientific_journal-4355	93	6	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	93	7	shedding	shedding	NOUN
american_scientific_journal-4355	93	8	and	and	CCONJ
american_scientific_journal-4355	93	9	a	a	DET
american_scientific_journal-4355	93	10	stable	stable	ADJ
american_scientific_journal-4355	93	11	soluble	soluble	ADJ
american_scientific_journal-4355	93	12	fragment	fragment	NOUN
american_scientific_journal-4355	93	13	is	be	AUX
american_scientific_journal-4355	93	14	produced	produce	VERB
american_scientific_journal-4355	93	15	which	which	PRON
american_scientific_journal-4355	93	16	sequesters	sequester	VERB
american_scientific_journal-4355	93	17	tgf	tgf	PROPN
american_scientific_journal-4355	93	18	-	-	PUNCT
american_scientific_journal-4355	93	19	β	β	NOUN
american_scientific_journal-4355	93	20	.	.	PUNCT
american_scientific_journal-4355	94	1	this	this	DET
american_scientific_journal-4355	94	2	fragment	fragment	NOUN
american_scientific_journal-4355	94	3	has	have	AUX
american_scientific_journal-4355	94	4	got	get	VERB
american_scientific_journal-4355	94	5	a	a	DET
american_scientific_journal-4355	94	6	therapeutic	therapeutic	ADJ
american_scientific_journal-4355	94	7	significant	significant	NOUN
american_scientific_journal-4355	94	8	in	in	ADP
american_scientific_journal-4355	94	9	some	some	DET
american_scientific_journal-4355	94	10	tumors	tumor	NOUN
american_scientific_journal-4355	94	11	and	and	CCONJ
american_scientific_journal-4355	94	12	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	94	13	as	as	ADP
american_scientific_journal-4355	94	14	an	an	DET
american_scientific_journal-4355	94	15	inhibitor	inhibitor	NOUN
american_scientific_journal-4355	94	16	of	of	ADP
american_scientific_journal-4355	94	17	tgf	tgf	PROPN
american_scientific_journal-4355	94	18	-	-	PUNCT
american_scientific_journal-4355	94	19	β	β	NOUN
american_scientific_journal-4355	94	20	signaling	signal	VERB
american_scientific_journal-4355	94	21	.	.	PUNCT
american_scientific_journal-4355	95	1	in	in	ADP
american_scientific_journal-4355	95	2	addition	addition	NOUN
american_scientific_journal-4355	95	3	to	to	ADP
american_scientific_journal-4355	95	4	the	the	DET
american_scientific_journal-4355	95	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	95	6	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	95	7	it	it	PRON
american_scientific_journal-4355	95	8	has	have	VERB
american_scientific_journal-4355	95	9	also	also	ADV
american_scientific_journal-4355	95	10	cytoplasmic	cytoplasmic	ADJ
american_scientific_journal-4355	95	11	domain	domain	NOUN
american_scientific_journal-4355	95	12	which	which	PRON
american_scientific_journal-4355	95	13	modulates	modulate	VERB
american_scientific_journal-4355	95	14	tgf	tgf	PROPN
american_scientific_journal-4355	95	15	-	-	PUNCT
american_scientific_journal-4355	95	16	β	β	X
american_scientific_journal-4355	95	17	dependent	dependent	ADJ
american_scientific_journal-4355	95	18	and	and	CCONJ
american_scientific_journal-4355	95	19	independent	independent	ADJ
american_scientific_journal-4355	95	20	activation	activation	NOUN
american_scientific_journal-4355	95	21	of	of	ADP
american_scientific_journal-4355	95	22	p38	p38	NOUN
american_scientific_journal-4355	95	23	/	/	SYM
american_scientific_journal-4355	95	24	mapk	mapk	NOUN
american_scientific_journal-4355	95	25	which	which	PRON
american_scientific_journal-4355	95	26	still	still	ADV
american_scientific_journal-4355	95	27	not	not	PART
american_scientific_journal-4355	95	28	well	well	ADV
american_scientific_journal-4355	95	29	known	know	VERB
american_scientific_journal-4355	95	30	,	,	PUNCT
american_scientific_journal-4355	95	31	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	95	32	also	also	ADV
american_scientific_journal-4355	95	33	forms	form	VERB
american_scientific_journal-4355	95	34	a	a	DET
american_scientific_journal-4355	95	35	complex	complex	NOUN
american_scientific_journal-4355	95	36	with	with	ADP
american_scientific_journal-4355	95	37	syndcan-2	syndcan-2	NUM
american_scientific_journal-4355	95	38	which	which	PRON
american_scientific_journal-4355	95	39	is	be	AUX
american_scientific_journal-4355	95	40	important	important	ADJ
american_scientific_journal-4355	95	41	in	in	ADP
american_scientific_journal-4355	95	42	regulating	regulate	VERB
american_scientific_journal-4355	95	43	tgf	tgf	PROPN
american_scientific_journal-4355	95	44	-	-	PUNCT
american_scientific_journal-4355	95	45	β	β	NOUN
american_scientific_journal-4355	95	46	signalling	signalling	NOUN
american_scientific_journal-4355	95	47	and	and	CCONJ
american_scientific_journal-4355	95	48	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	95	49	.	.	PUNCT
american_scientific_journal-4355	96	1	so	so	ADV
american_scientific_journal-4355	96	2	investigations	investigation	NOUN
american_scientific_journal-4355	96	3	to	to	PART
american_scientific_journal-4355	96	4	explore	explore	VERB
american_scientific_journal-4355	96	5	the	the	DET
american_scientific_journal-4355	96	6	fate	fate	NOUN
american_scientific_journal-4355	96	7	of	of	ADP
american_scientific_journal-4355	96	8	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	96	9	fragment	fragment	PROPN
american_scientific_journal-4355	96	10	after	after	SCONJ
american_scientific_journal-4355	96	11	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	96	12	cleavage	cleavage	NOUN
american_scientific_journal-4355	96	13	is	be	AUX
american_scientific_journal-4355	96	14	our	our	PRON
american_scientific_journal-4355	96	15	target	target	NOUN
american_scientific_journal-4355	96	16	,	,	PUNCT
american_scientific_journal-4355	96	17	so	so	ADV
american_scientific_journal-4355	96	18	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	96	19	ectodomain	ectodomain	PROPN
american_scientific_journal-4355	96	20	cleavage	cleavage	NOUN
american_scientific_journal-4355	96	21	considered	consider	VERB
american_scientific_journal-4355	96	22	a	a	DET
american_scientific_journal-4355	96	23	substrate	substrate	NOUN
american_scientific_journal-4355	96	24	for	for	ADP
american_scientific_journal-4355	96	25	γ	γ	NOUN
american_scientific_journal-4355	96	26	-	-	NOUN
american_scientific_journal-4355	96	27	secretase	secretase	NOUN
american_scientific_journal-4355	96	28	and	and	CCONJ
american_scientific_journal-4355	96	29	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	96	30	transmembrane	transmembrane	NOUN
american_scientific_journal-4355	96	31	-	-	PUNCT
american_scientific_journal-4355	96	32	cytobetaglycan	cytobetaglycan	PROPN
american_scientific_journal-4355	96	33	is	be	AUX
american_scientific_journal-4355	96	34	known	know	VERB
american_scientific_journal-4355	96	35	to	to	PART
american_scientific_journal-4355	96	36	be	be	AUX
american_scientific_journal-4355	96	37	a	a	DET
american_scientific_journal-4355	96	38	proteoglycan	proteoglycan	ADJ
american_scientific_journal-4355	96	39	tgf	tgf	PROPN
american_scientific_journal-4355	96	40	-	-	PUNCT
american_scientific_journal-4355	96	41	β	β	X
american_scientific_journal-4355	96	42	co	co	NOUN
american_scientific_journal-4355	96	43	-	-	NOUN
american_scientific_journal-4355	96	44	receptor	receptor	NOUN
american_scientific_journal-4355	96	45	for	for	ADP
american_scientific_journal-4355	96	46	tgf	tgf	PROPN
american_scientific_journal-4355	96	47	-	-	PUNCT
american_scientific_journal-4355	96	48	β	β	NOUN
american_scientific_journal-4355	96	49	ligands	ligand	NOUN
american_scientific_journal-4355	96	50	,	,	PUNCT
american_scientific_journal-4355	96	51	transmembrane	transmembrane	NOUN
american_scientific_journal-4355	96	52	-	-	PUNCT
american_scientific_journal-4355	96	53	cytoplasmic	cytoplasmic	ADJ
american_scientific_journal-4355	96	54	fragment	fragment	NOUN
american_scientific_journal-4355	96	55	will	will	AUX
american_scientific_journal-4355	96	56	be	be	AUX
american_scientific_journal-4355	96	57	stable	stable	ADJ
american_scientific_journal-4355	96	58	after	after	ADP
american_scientific_journal-4355	96	59	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	96	60	cleavage	cleavage	NOUN
american_scientific_journal-4355	96	61	,	,	PUNCT
american_scientific_journal-4355	96	62	this	this	PRON
american_scientific_journal-4355	96	63	gives	give	VERB
american_scientific_journal-4355	96	64	rise	rise	NOUN
american_scientific_journal-4355	96	65	to	to	ADP
american_scientific_journal-4355	96	66	an	an	DET
american_scientific_journal-4355	96	67	implication	implication	NOUN
american_scientific_journal-4355	96	68	for	for	ADP
american_scientific_journal-4355	96	69	tgf	tgf	PROPN
american_scientific_journal-4355	96	70	-	-	PUNCT
american_scientific_journal-4355	96	71	β	β	NOUN
american_scientific_journal-4355	96	72	effects	effect	NOUN
american_scientific_journal-4355	96	73	and	and	CCONJ
american_scientific_journal-4355	96	74	response	response	NOUN
american_scientific_journal-4355	96	75	.	.	PUNCT
american_scientific_journal-4355	97	1	endogline	endogline	PROPN
american_scientific_journal-4355	97	2	despite	despite	SCONJ
american_scientific_journal-4355	97	3	of	of	ADP
american_scientific_journal-4355	97	4	being	be	AUX
american_scientific_journal-4355	97	5	functionally	functionally	ADV
american_scientific_journal-4355	97	6	important	important	ADJ
american_scientific_journal-4355	97	7	,	,	PUNCT
american_scientific_journal-4355	97	8	it	it	PRON
american_scientific_journal-4355	97	9	is	be	AUX
american_scientific_journal-4355	97	10	found	find	VERB
american_scientific_journal-4355	97	11	in	in	ADP
american_scientific_journal-4355	97	12	two	two	NUM
american_scientific_journal-4355	97	13	forms	form	NOUN
american_scientific_journal-4355	97	14	,	,	PUNCT
american_scientific_journal-4355	97	15	its	its	PRON
american_scientific_journal-4355	97	16	mutation	mutation	NOUN
american_scientific_journal-4355	97	17	yields	yield	VERB
american_scientific_journal-4355	97	18	impaired	impaired	ADJ
american_scientific_journal-4355	97	19	coordination	coordination	NOUN
american_scientific_journal-4355	97	20	of	of	ADP
american_scientific_journal-4355	97	21	tgf	tgf	PROPN
american_scientific_journal-4355	97	22	-	-	PUNCT
american_scientific_journal-4355	97	23	β	β	NOUN
american_scientific_journal-4355	97	24	signalling	signal	VERB
american_scientific_journal-4355	97	25	complexes	complex	NOUN
american_scientific_journal-4355	97	26	and	and	CCONJ
american_scientific_journal-4355	97	27	play	play	VERB
american_scientific_journal-4355	97	28	a	a	DET
american_scientific_journal-4355	97	29	role	role	NOUN
american_scientific_journal-4355	97	30	in	in	ADP
american_scientific_journal-4355	97	31	controlling	control	VERB
american_scientific_journal-4355	97	32	cell	cell	NOUN
american_scientific_journal-4355	97	33	migration	migration	NOUN
american_scientific_journal-4355	97	34	and	and	CCONJ
american_scientific_journal-4355	97	35	adhesion	adhesion	NOUN
american_scientific_journal-4355	97	36	composition	composition	NOUN
american_scientific_journal-4355	97	37	.	.	PUNCT
american_scientific_journal-4355	98	1	ectodomain	ectodomain	PROPN
american_scientific_journal-4355	98	2	shedding	shedding	NOUN
american_scientific_journal-4355	98	3	and	and	CCONJ
american_scientific_journal-4355	98	4	γ	γ	NOUN
american_scientific_journal-4355	98	5	-	-	PUNCT
american_scientific_journal-4355	98	6	secretase	secretase	NOUN
american_scientific_journal-4355	98	7	-	-	PUNCT
american_scientific_journal-4355	98	8	dependent	dependent	ADJ
american_scientific_journal-4355	98	9	release	release	NOUN
american_scientific_journal-4355	98	10	of	of	ADP
american_scientific_journal-4355	98	11	an	an	DET
american_scientific_journal-4355	98	12	intracellular	intracellular	ADJ
american_scientific_journal-4355	98	13	domain	domain	NOUN
american_scientific_journal-4355	98	14	,	,	PUNCT
american_scientific_journal-4355	98	15	an	an	DET
american_scientific_journal-4355	98	16	implication	implication	NOUN
american_scientific_journal-4355	98	17	is	be	AUX
american_scientific_journal-4355	98	18	important	important	ADJ
american_scientific_journal-4355	98	19	tgf	tgf	PROPN
american_scientific_journal-4355	98	20	-	-	PUNCT
american_scientific_journal-4355	98	21	β	β	PROPN
american_scientific_journal-4355	98	22	signal	signal	NOUN
american_scientific_journal-4355	98	23	transduction	transduction	NOUN
american_scientific_journal-4355	98	24	,	,	PUNCT
american_scientific_journal-4355	98	25	on	on	ADP
american_scientific_journal-4355	98	26	the	the	DET
american_scientific_journal-4355	98	27	other	other	ADJ
american_scientific_journal-4355	98	28	hand	hand	NOUN
american_scientific_journal-4355	98	29	γ	γ	NOUN
american_scientific_journal-4355	98	30	-	-	PUNCT
american_scientific_journal-4355	98	31	secretase	secretase	ADJ
american_scientific_journal-4355	98	32	inhibition	inhibition	NOUN
american_scientific_journal-4355	98	33	also	also	ADV
american_scientific_journal-4355	98	34	has	have	VERB
american_scientific_journal-4355	98	35	a	a	DET
american_scientific_journal-4355	98	36	significant	significant	ADJ
american_scientific_journal-4355	98	37	impact	impact	NOUN
american_scientific_journal-4355	98	38	on	on	ADP
american_scientific_journal-4355	98	39	tgf	tgf	PROPN
american_scientific_journal-4355	98	40	-	-	PUNCT
american_scientific_journal-4355	98	41	β	β	NOUN
american_scientific_journal-4355	98	42	signalling	signalling	NOUN
american_scientific_journal-4355	98	43	.	.	PUNCT
american_scientific_journal-4355	99	1	betaglcan	betaglcan	ADJ
american_scientific_journal-4355	99	2	species	specie	NOUN
american_scientific_journal-4355	99	3	have	have	VERB
american_scientific_journal-4355	99	4	opposing	oppose	VERB
american_scientific_journal-4355	99	5	effects	effect	NOUN
american_scientific_journal-4355	99	6	on	on	ADP
american_scientific_journal-4355	99	7	tgf	tgf	PROPN
american_scientific_journal-4355	99	8	-	-	PUNCT
american_scientific_journal-4355	99	9	β	β	NOUN
american_scientific_journal-4355	99	10	signalling	signal	VERB
american_scientific_journal-4355	99	11	whereby	whereby	SCONJ
american_scientific_journal-4355	99	12	betaglycan	betaglycan	AUX
american_scientific_journal-4355	99	13	serving	serve	VERB
american_scientific_journal-4355	99	14	as	as	ADP
american_scientific_journal-4355	99	15	(	(	PUNCT
american_scientific_journal-4355	99	16	molecular	molecular	ADJ
american_scientific_journal-4355	99	17	switch	switch	NOUN
american_scientific_journal-4355	99	18	)	)	PUNCT
american_scientific_journal-4355	99	19	.when	.when	ADV
american_scientific_journal-4355	99	20	isolated	isolate	VERB
american_scientific_journal-4355	99	21	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	99	22	cytoplasmic	cytoplasmic	ADJ
american_scientific_journal-4355	99	23	domain	domain	NOUN
american_scientific_journal-4355	99	24	is	be	AUX
american_scientific_journal-4355	99	25	inhibited	inhibit	VERB
american_scientific_journal-4355	99	26	it	it	PRON
american_scientific_journal-4355	99	27	leads	lead	VERB
american_scientific_journal-4355	99	28	to	to	PART
american_scientific_journal-4355	99	29	decrease	decrease	VERB
american_scientific_journal-4355	99	30	tgf	tgf	PROPN
american_scientific_journal-4355	99	31	-	-	PUNCT
american_scientific_journal-4355	99	32	β	β	NOUN
american_scientific_journal-4355	99	33	signaling	signal	VERB
american_scientific_journal-4355	99	34	through	through	ADP
american_scientific_journal-4355	99	35	activation	activation	NOUN
american_scientific_journal-4355	99	36	of	of	ADP
american_scientific_journal-4355	99	37	the	the	DET
american_scientific_journal-4355	99	38	p38	p38	NOUN
american_scientific_journal-4355	99	39	/	/	SYM
american_scientific_journal-4355	99	40	mapk	mapk	NOUN
american_scientific_journal-4355	99	41	pathway	pathway	NOUN
american_scientific_journal-4355	99	42	,	,	PUNCT
american_scientific_journal-4355	99	43	so	so	ADV
american_scientific_journal-4355	99	44	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	99	45	has	have	AUX
american_scientific_journal-4355	99	46	got	get	VERB
american_scientific_journal-4355	99	47	an	an	DET
american_scientific_journal-4355	99	48	essential	essential	ADJ
american_scientific_journal-4355	99	49	role	role	NOUN
american_scientific_journal-4355	99	50	in	in	ADP
american_scientific_journal-4355	99	51	mediating	mediate	VERB
american_scientific_journal-4355	99	52	the	the	DET
american_scientific_journal-4355	99	53	specificity	specificity	NOUN
american_scientific_journal-4355	99	54	of	of	ADP
american_scientific_journal-4355	99	55	tgf	tgf	PROPN
american_scientific_journal-4355	99	56	-	-	PUNCT
american_scientific_journal-4355	99	57	β	β	PROPN
american_scientific_journal-4355	99	58	signaling	signal	VERB
american_scientific_journal-4355	99	59	pathways	pathway	NOUN
american_scientific_journal-4355	99	60	.	.	PUNCT
american_scientific_journal-4355	100	1	the	the	DET
american_scientific_journal-4355	100	2	structure	structure	NOUN
american_scientific_journal-4355	100	3	of	of	ADP
american_scientific_journal-4355	100	4	betaglycan,(figure	betaglycan,(figure	NOUN
american_scientific_journal-4355	100	5	3	3	NUM
american_scientific_journal-4355	100	6	)	)	PUNCT
american_scientific_journal-4355	100	7	is	be	AUX
american_scientific_journal-4355	100	8	a	a	DET
american_scientific_journal-4355	100	9	polymorphic	polymorphic	ADJ
american_scientific_journal-4355	100	10	membrane	membrane	NOUN
american_scientific_journal-4355	100	11	-	-	PUNCT
american_scientific_journal-4355	100	12	anchored	anchor	VERB
american_scientific_journal-4355	100	13	proteoglycan	proteoglycan	NOUN
american_scientific_journal-4355	100	14	with	with	ADP
american_scientific_journal-4355	100	15	high	high	ADJ
american_scientific_journal-4355	100	16	affinity	affinity	NOUN
american_scientific_journal-4355	100	17	for	for	ADP
american_scientific_journal-4355	100	18	transforming	transform	VERB
american_scientific_journal-4355	100	19	growth	growth	NOUN
american_scientific_journal-4355	100	20	factor	factor	NOUN
american_scientific_journal-4355	100	21	-	-	PUNCT
american_scientific_journal-4355	100	22	β	β	X
american_scientific_journal-4355	100	23	(	(	PUNCT
american_scientific_journal-4355	100	24	tgf	tgf	PROPN
american_scientific_journal-4355	100	25	-	-	PUNCT
american_scientific_journal-4355	100	26	β	β	NOUN
american_scientific_journal-4355	100	27	)	)	PUNCT
american_scientific_journal-4355	100	28	.	.	PUNCT
american_scientific_journal-4355	101	1	as	as	SCONJ
american_scientific_journal-4355	101	2	produced	produce	VERB
american_scientific_journal-4355	101	3	from	from	ADP
american_scientific_journal-4355	101	4	its	its	PRON
american_scientific_journal-4355	101	5	cdna	cdna	PROPN
american_scientific_journal-4355	101	6	sequence	sequence	NOUN
american_scientific_journal-4355	101	7	,	,	PUNCT
american_scientific_journal-4355	101	8	the	the	DET
american_scientific_journal-4355	101	9	853	853	NUM
american_scientific_journal-4355	101	10	amino	amino	NOUN
american_scientific_journal-4355	101	11	acid	acid	NOUN
american_scientific_journal-4355	101	12	core	core	NOUN
american_scientific_journal-4355	101	13	protein	protein	NOUN
american_scientific_journal-4355	101	14	of	of	ADP
american_scientific_journal-4355	101	15	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	101	16	has	have	VERB
american_scientific_journal-4355	101	17	an	an	DET
american_scientific_journal-4355	101	18	extracellular	extracellular	ADJ
american_scientific_journal-4355	101	19	domain	domain	NOUN
american_scientific_journal-4355	101	20	with	with	ADP
american_scientific_journal-4355	101	21	different	different	ADJ
american_scientific_journal-4355	101	22	sites	site	NOUN
american_scientific_journal-4355	101	23	for	for	ADP
american_scientific_journal-4355	101	24	glycosaminoglycan	glycosaminoglycan	PROPN
american_scientific_journal-4355	101	25	(	(	PUNCT
american_scientific_journal-4355	101	26	gag	gag	NOUN
american_scientific_journal-4355	101	27	)	)	PUNCT
american_scientific_journal-4355	101	28	chains	chain	NOUN
american_scientific_journal-4355	101	29	attachment	attachment	NOUN
american_scientific_journal-4355	101	30	.	.	PUNCT
american_scientific_journal-4355	102	1	despite	despite	SCONJ
american_scientific_journal-4355	102	2	these	these	DET
american_scientific_journal-4355	102	3	chains	chain	NOUN
american_scientific_journal-4355	102	4	not	not	PART
american_scientific_journal-4355	102	5	being	be	AUX
american_scientific_journal-4355	102	6	necessarily	necessarily	ADV
american_scientific_journal-4355	102	7	important	important	ADJ
american_scientific_journal-4355	102	8	for	for	SCONJ
american_scientific_journal-4355	102	9	tgf	tgf	PROPN
american_scientific_journal-4355	102	10	-	-	PUNCT
american_scientific_journal-4355	102	11	β	β	NOUN
american_scientific_journal-4355	102	12	binding	bind	VERB
american_scientific_journal-4355	102	13	to	to	ADP
american_scientific_journal-4355	102	14	the	the	DET
american_scientific_journal-4355	102	15	core	core	NOUN
american_scientific_journal-4355	102	16	protein	protein	NOUN
american_scientific_journal-4355	102	17	,	,	PUNCT
american_scientific_journal-4355	102	18	they	they	PRON
american_scientific_journal-4355	102	19	are	be	AUX
american_scientific_journal-4355	102	20	an	an	DET
american_scientific_journal-4355	102	21	important	important	ADJ
american_scientific_journal-4355	102	22	component	component	NOUN
american_scientific_journal-4355	102	23	of	of	ADP
american_scientific_journal-4355	102	24	connective	connective	ADJ
american_scientific_journal-4355	102	25	tissues	tissue	NOUN
american_scientific_journal-4355	102	26	,	,	PUNCT
american_scientific_journal-4355	102	27	and	and	CCONJ
american_scientific_journal-4355	102	28	may	may	AUX
american_scientific_journal-4355	102	29	be	be	AUX
american_scientific_journal-4355	102	30	covalently	covalently	ADV
american_scientific_journal-4355	102	31	linked	link	VERB
american_scientific_journal-4355	102	32	to	to	ADP
american_scientific_journal-4355	102	33	a	a	DET
american_scientific_journal-4355	102	34	protein	protein	NOUN
american_scientific_journal-4355	102	35	to	to	PART
american_scientific_journal-4355	102	36	form	form	VERB
american_scientific_journal-4355	102	37	proteoglycans	proteoglycan	NOUN
american_scientific_journal-4355	102	38	.	.	PUNCT
american_scientific_journal-4355	103	1	(	(	PUNCT
american_scientific_journal-4355	103	2	adapted	adapt	VERB
american_scientific_journal-4355	103	3	online	online	ADV
american_scientific_journal-4355	103	4	at	at	ADP
american_scientific_journal-4355	103	5	www.med.unibs.it/%7eairc/hspgs.htm	www.med.unibs.it/%7eairc/hspgs.htm	NOUN
american_scientific_journal-4355	103	6	)	)	PUNCT
american_scientific_journal-4355	103	7	.	.	PUNCT
american_scientific_journal-4355	104	1	figure	figure	VERB
american_scientific_journal-4355	104	2	3	3	NUM
american_scientific_journal-4355	104	3	:	:	PUNCT
american_scientific_journal-4355	104	4	structure	structure	NOUN
american_scientific_journal-4355	104	5	of	of	ADP
american_scientific_journal-4355	104	6	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	104	7	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	104	8	appears	appear	VERB
american_scientific_journal-4355	104	9	to	to	PART
american_scientific_journal-4355	104	10	deliver	deliver	VERB
american_scientific_journal-4355	104	11	tgf	tgf	PROPN
american_scientific_journal-4355	104	12	-	-	PUNCT
american_scientific_journal-4355	104	13	β	β	NOUN
american_scientific_journal-4355	104	14	to	to	ADP
american_scientific_journal-4355	104	15	the	the	DET
american_scientific_journal-4355	104	16	signaling	signal	VERB
american_scientific_journal-4355	104	17	receptors	receptor	NOUN
american_scientific_journal-4355	104	18	[	[	X
american_scientific_journal-4355	104	19	20	20	NUM
american_scientific_journal-4355	104	20	]	]	PUNCT
american_scientific_journal-4355	104	21	.	.	PUNCT
american_scientific_journal-4355	105	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	105	2	binds	bind	VERB
american_scientific_journal-4355	105	3	tgf	tgf	PROPN
american_scientific_journal-4355	105	4	-	-	PUNCT
american_scientific_journal-4355	105	5	β	β	NOUN
american_scientific_journal-4355	105	6	through	through	ADP
american_scientific_journal-4355	105	7	the	the	DET
american_scientific_journal-4355	105	8	core	core	NOUN
american_scientific_journal-4355	105	9	protein	protein	NOUN
american_scientific_journal-4355	105	10	[	[	X
american_scientific_journal-4355	105	11	21	21	NUM
american_scientific_journal-4355	105	12	]	]	PUNCT
american_scientific_journal-4355	105	13	.	.	PUNCT
american_scientific_journal-4355	106	1	the	the	DET
american_scientific_journal-4355	106	2	localization	localization	NOUN
american_scientific_journal-4355	106	3	of	of	ADP
american_scientific_journal-4355	106	4	the	the	DET
american_scientific_journal-4355	106	5	tgf	tgf	PROPN
american_scientific_journal-4355	106	6	-	-	PUNCT
american_scientific_journal-4355	106	7	β	β	NOUN
american_scientific_journal-4355	106	8	-	-	ADJ
american_scientific_journal-4355	106	9	binding	bind	VERB
american_scientific_journal-4355	106	10	site	site	NOUN
american_scientific_journal-4355	106	11	in	in	ADP
american_scientific_journal-4355	106	12	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	106	13	is	be	AUX
american_scientific_journal-4355	106	14	unclear	unclear	ADJ
american_scientific_journal-4355	106	15	.	.	PUNCT
american_scientific_journal-4355	107	1	there	there	PRON
american_scientific_journal-4355	107	2	are	be	VERB
american_scientific_journal-4355	107	3	at	at	ADV
american_scientific_journal-4355	107	4	least	least	ADJ
american_scientific_journal-4355	107	5	two	two	NUM
american_scientific_journal-4355	107	6	independently	independently	ADV
american_scientific_journal-4355	107	7	active	active	ADJ
american_scientific_journal-4355	107	8	tgf	tgf	PROPN
american_scientific_journal-4355	107	9	-	-	PUNCT
american_scientific_journal-4355	107	10	β	β	X
american_scientific_journal-4355	107	11	binding	bind	VERB
american_scientific_journal-4355	107	12	sites	site	NOUN
american_scientific_journal-4355	107	13	in	in	ADP
american_scientific_journal-4355	107	14	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	107	15	,	,	PUNCT
american_scientific_journal-4355	107	16	one	one	NUM
american_scientific_journal-4355	107	17	in	in	ADP
american_scientific_journal-4355	107	18	the	the	DET
american_scientific_journal-4355	107	19	n	n	CCONJ
american_scientific_journal-4355	107	20	-	-	PUNCT
american_scientific_journal-4355	107	21	terminal	terminal	ADJ
american_scientific_journal-4355	107	22	two	two	NUM
american_scientific_journal-4355	107	23	thirds	third	NOUN
american_scientific_journal-4355	107	24	of	of	ADP
american_scientific_journal-4355	107	25	the	the	DET
american_scientific_journal-4355	107	26	extracellular	extracellular	ADJ
american_scientific_journal-4355	107	27	domain	domain	NOUN
american_scientific_journal-4355	107	28	of	of	ADP
american_scientific_journal-4355	107	29	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	107	30	and	and	CCONJ
american_scientific_journal-4355	107	31	another	another	PRON
american_scientific_journal-4355	107	32	in	in	ADP
american_scientific_journal-4355	107	33	the	the	DET
american_scientific_journal-4355	107	34	c	c	NOUN
american_scientific_journal-4355	107	35	-	-	PUNCT
american_scientific_journal-4355	107	36	terminal	terminal	ADJ
american_scientific_journal-4355	107	37	one	one	NUM
american_scientific_journal-4355	107	38	-	-	PUNCT
american_scientific_journal-4355	107	39	third	third	NOUN
american_scientific_journal-4355	107	40	.	.	PUNCT
american_scientific_journal-4355	108	1	these	these	DET
american_scientific_journal-4355	108	2	binding	bind	VERB
american_scientific_journal-4355	108	3	sites	site	NOUN
american_scientific_journal-4355	108	4	exhibit	exhibit	VERB
american_scientific_journal-4355	108	5	similar	similar	ADJ
american_scientific_journal-4355	108	6	binding	bind	VERB
american_scientific_journal-4355	108	7	specificities	specificity	NOUN
american_scientific_journal-4355	108	8	and	and	CCONJ
american_scientific_journal-4355	108	9	representing	represent	VERB
american_scientific_journal-4355	108	10	the	the	DET
american_scientific_journal-4355	108	11	n	n	ADV
american_scientific_journal-4355	108	12	-	-	PUNCT
american_scientific_journal-4355	108	13	terminal	terminal	ADJ
american_scientific_journal-4355	108	14	and	and	CCONJ
american_scientific_journal-4355	108	15	c	c	NOUN
american_scientific_journal-4355	108	16	-	-	PUNCT
american_scientific_journal-4355	108	17	terminal	terminal	ADJ
american_scientific_journal-4355	108	18	binding	bind	VERB
american_scientific_journal-4355	108	19	sites	site	NOUN
american_scientific_journal-4355	108	20	enhance	enhance	VERB
american_scientific_journal-4355	108	21	the	the	DET
american_scientific_journal-4355	108	22	bioactivity	bioactivity	NOUN
american_scientific_journal-4355	108	23	of	of	ADP
american_scientific_journal-4355	108	24	tgf	tgf	PROPN
american_scientific_journal-4355	108	25	-	-	PUNCT
american_scientific_journal-4355	108	26	β	β	NOUN
american_scientific_journal-4355	108	27	.	.	PUNCT
american_scientific_journal-4355	109	1	this	this	DET
american_scientific_journal-4355	109	2	enhancing	enhance	VERB
american_scientific_journal-4355	109	3	effect	effect	NOUN
american_scientific_journal-4355	109	4	was	be	AUX
american_scientific_journal-4355	109	5	observed	observe	VERB
american_scientific_journal-4355	109	6	not	not	PART
american_scientific_journal-4355	109	7	only	only	ADV
american_scientific_journal-4355	109	8	in	in	ADP
american_scientific_journal-4355	109	9	the	the	DET
american_scientific_journal-4355	109	10	growth	growth	NOUN
american_scientific_journal-4355	109	11	inhibitory	inhibitory	ADJ
american_scientific_journal-4355	109	12	activity	activity	NOUN
american_scientific_journal-4355	109	13	of	of	ADP
american_scientific_journal-4355	109	14	tgf	tgf	PROPN
american_scientific_journal-4355	109	15	-	-	PUNCT
american_scientific_journal-4355	109	16	β	β	PROPN
american_scientific_journal-4355	109	17	but	but	CCONJ
american_scientific_journal-4355	109	18	also	also	ADV
american_scientific_journal-4355	109	19	in	in	ADP
american_scientific_journal-4355	109	20	the	the	DET
american_scientific_journal-4355	109	21	stimulating	stimulating	ADJ
american_scientific_journal-4355	109	22	effect	effect	NOUN
american_scientific_journal-4355	109	23	of	of	ADP
american_scientific_journal-4355	109	24	tgf	tgf	PROPN
american_scientific_journal-4355	109	25	-	-	PUNCT
american_scientific_journal-4355	109	26	β	β	PROPN
american_scientific_journal-4355	109	27	on	on	ADP
american_scientific_journal-4355	109	28	the	the	DET
american_scientific_journal-4355	109	29	matrix	matrix	NOUN
american_scientific_journal-4355	109	30	synthesis	synthesis	NOUN
american_scientific_journal-4355	109	31	.	.	PUNCT
american_scientific_journal-4355	110	1	in	in	ADP
american_scientific_journal-4355	110	2	addition	addition	NOUN
american_scientific_journal-4355	110	3	to	to	ADP
american_scientific_journal-4355	110	4	a	a	DET
american_scientific_journal-4355	110	5	membrane	membrane	NOUN
american_scientific_journal-4355	110	6	-	-	PUNCT
american_scientific_journal-4355	110	7	bound	bind	VERB
american_scientific_journal-4355	110	8	form	form	NOUN
american_scientific_journal-4355	110	9	,	,	PUNCT
american_scientific_journal-4355	110	10	there	there	PRON
american_scientific_journal-4355	110	11	is	be	VERB
american_scientific_journal-4355	110	12	a	a	DET
american_scientific_journal-4355	110	13	soluble	soluble	ADJ
american_scientific_journal-4355	110	14	form	form	NOUN
american_scientific_journal-4355	110	15	of	of	ADP
american_scientific_journal-4355	110	16	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	110	17	as	as	ADV
american_scientific_journal-4355	110	18	well	well	ADV
american_scientific_journal-4355	110	19	,	,	PUNCT
american_scientific_journal-4355	110	20	generated	generate	VERB
american_scientific_journal-4355	110	21	by	by	ADP
american_scientific_journal-4355	110	22	the	the	DET
american_scientific_journal-4355	110	23	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	110	24	shedding	shedding	NOUN
american_scientific_journal-4355	110	25	of	of	ADP
american_scientific_journal-4355	110	26	the	the	DET
american_scientific_journal-4355	110	27	cell	cell	NOUN
american_scientific_journal-4355	110	28	surface	surface	NOUN
american_scientific_journal-4355	110	29	receptor	receptor	NOUN
american_scientific_journal-4355	110	30	.	.	PUNCT
american_scientific_journal-4355	111	1	although	although	SCONJ
american_scientific_journal-4355	111	2	the	the	DET
american_scientific_journal-4355	111	3	membrane	membrane	NOUN
american_scientific_journal-4355	111	4	-	-	PUNCT
american_scientific_journal-4355	111	5	bound	bind	VERB
american_scientific_journal-4355	111	6	form	form	NOUN
american_scientific_journal-4355	111	7	presents	present	NOUN
american_scientific_journal-4355	111	8	ligand	ligand	NOUN
american_scientific_journal-4355	111	9	,	,	PUNCT
american_scientific_journal-4355	111	10	the	the	DET
american_scientific_journal-4355	111	11	soluble	soluble	ADJ
american_scientific_journal-4355	111	12	form	form	NOUN
american_scientific_journal-4355	111	13	is	be	AUX
american_scientific_journal-4355	111	14	thought	think	VERB
american_scientific_journal-4355	111	15	to	to	PART
american_scientific_journal-4355	111	16	sequester	sequester	VERB
american_scientific_journal-4355	111	17	ligand	ligand	NOUN
american_scientific_journal-4355	111	18	from	from	ADP
american_scientific_journal-4355	111	19	the	the	DET
american_scientific_journal-4355	111	20	serine	serine	NOUN
american_scientific_journal-4355	111	21	/	/	SYM
american_scientific_journal-4355	111	22	threonine	threonine	NOUN
american_scientific_journal-4355	111	23	tgf	tgf	PROPN
american_scientific_journal-4355	111	24	-	-	PUNCT
american_scientific_journal-4355	111	25	ß	ß	NOUN
american_scientific_journal-4355	111	26	signalling	signal	VERB
american_scientific_journal-4355	111	27	receptors	receptor	NOUN
american_scientific_journal-4355	111	28	.	.	PUNCT
american_scientific_journal-4355	112	1	this	this	DET
american_scientific_journal-4355	112	2	sequestering	sequestering	NOUN
american_scientific_journal-4355	112	3	role	role	NOUN
american_scientific_journal-4355	112	4	may	may	AUX
american_scientific_journal-4355	112	5	be	be	AUX
american_scientific_journal-4355	112	6	of	of	ADP
american_scientific_journal-4355	112	7	benefit	benefit	NOUN
american_scientific_journal-4355	112	8	in	in	ADP
american_scientific_journal-4355	112	9	later	later	ADJ
american_scientific_journal-4355	112	10	stage	stage	NOUN
american_scientific_journal-4355	112	11	tumours	tumour	VERB
american_scientific_journal-4355	112	12	,	,	PUNCT
american_scientific_journal-4355	112	13	where	where	SCONJ
american_scientific_journal-4355	112	14	excess	excess	ADJ
american_scientific_journal-4355	112	15	tgf	tgf	PROPN
american_scientific_journal-4355	112	16	-	-	PUNCT
american_scientific_journal-4355	112	17	β	β	PROPN
american_scientific_journal-4355	112	18	may	may	AUX
american_scientific_journal-4355	112	19	assist	assist	VERB
american_scientific_journal-4355	112	20	in	in	ADP
american_scientific_journal-4355	112	21	tumour	tumour	NOUN
american_scientific_journal-4355	112	22	growth	growth	NOUN
american_scientific_journal-4355	112	23	by	by	ADP
american_scientific_journal-4355	112	24	enhancing	enhance	VERB
american_scientific_journal-4355	112	25	epithelial	epithelial	NOUN
american_scientific_journal-4355	112	26	to	to	ADP
american_scientific_journal-4355	112	27	mesenchymal	mesenchymal	ADJ
american_scientific_journal-4355	112	28	transitions	transition	NOUN
american_scientific_journal-4355	112	29	,	,	PUNCT
american_scientific_journal-4355	112	30	mmp	mmp	PROPN
american_scientific_journal-4355	112	31	(	(	PUNCT
american_scientific_journal-4355	112	32	matrix	matrix	NOUN
american_scientific_journal-4355	112	33	metalloproteinase	metalloproteinase	NOUN
american_scientific_journal-4355	112	34	)	)	PUNCT
american_scientific_journal-4355	112	35	expression	expression	NOUN
american_scientific_journal-4355	112	36	,	,	PUNCT
american_scientific_journal-4355	112	37	and	and	CCONJ
american_scientific_journal-4355	112	38	basement	basement	NOUN
american_scientific_journal-4355	112	39	membrane	membrane	NOUN
american_scientific_journal-4355	112	40	degradation	degradation	NOUN
american_scientific_journal-4355	113	1	[	[	X
american_scientific_journal-4355	113	2	22	22	NUM
american_scientific_journal-4355	113	3	]	]	PUNCT
american_scientific_journal-4355	113	4	.	.	PUNCT
american_scientific_journal-4355	114	1	furthermore	furthermore	ADV
american_scientific_journal-4355	114	2	,	,	PUNCT
american_scientific_journal-4355	114	3	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	114	4	,	,	PUNCT
american_scientific_journal-4355	114	5	a	a	DET
american_scientific_journal-4355	114	6	cell	cell	NOUN
american_scientific_journal-4355	114	7	surface	surface	NOUN
american_scientific_journal-4355	114	8	heparan	heparan	ADJ
american_scientific_journal-4355	114	9	sulphate	sulphate	NOUN
american_scientific_journal-4355	114	10	proteoglycan	proteoglycan	ADJ
american_scientific_journal-4355	114	11	,	,	PUNCT
american_scientific_journal-4355	114	12	is	be	AUX
american_scientific_journal-4355	114	13	traditionally	traditionally	ADV
american_scientific_journal-4355	114	14	thought	think	VERB
american_scientific_journal-4355	114	15	to	to	PART
american_scientific_journal-4355	114	16	function	function	VERB
american_scientific_journal-4355	114	17	by	by	ADP
american_scientific_journal-4355	114	18	binding	bind	VERB
american_scientific_journal-4355	114	19	transforming	transform	VERB
american_scientific_journal-4355	114	20	growth	growth	NOUN
american_scientific_journal-4355	114	21	factor	factor	NOUN
american_scientific_journal-4355	114	22	type	type	NOUN
american_scientific_journal-4355	114	23	β	β	X
american_scientific_journal-4355	114	24	(	(	PUNCT
american_scientific_journal-4355	114	25	tgf	tgf	PROPN
american_scientific_journal-4355	114	26	-	-	PUNCT
american_scientific_journal-4355	114	27	β	β	NOUN
american_scientific_journal-4355	114	28	)	)	PUNCT
american_scientific_journal-4355	114	29	via	via	ADP
american_scientific_journal-4355	114	30	its	its	PRON
american_scientific_journal-4355	114	31	core	core	NOUN
american_scientific_journal-4355	114	32	protein	protein	NOUN
american_scientific_journal-4355	114	33	and	and	CCONJ
american_scientific_journal-4355	114	34	then	then	ADV
american_scientific_journal-4355	114	35	transferring	transfer	VERB
american_scientific_journal-4355	114	36	the	the	DET
american_scientific_journal-4355	114	37	growth	growth	NOUN
american_scientific_journal-4355	114	38	factor	factor	NOUN
american_scientific_journal-4355	114	39	to	to	ADP
american_scientific_journal-4355	114	40	its	its	PRON
american_scientific_journal-4355	114	41	signalling	signal	VERB
american_scientific_journal-4355	114	42	receptor	receptor	NOUN
american_scientific_journal-4355	114	43	,	,	PUNCT
american_scientific_journal-4355	114	44	the	the	DET
american_scientific_journal-4355	114	45	type	type	NOUN
american_scientific_journal-4355	114	46	ii	ii	NOUN
american_scientific_journal-4355	114	47	receptor	receptor	NOUN
american_scientific_journal-4355	114	48	.	.	PUNCT
american_scientific_journal-4355	115	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	115	2	induces	induce	VERB
american_scientific_journal-4355	115	3	tgf	tgf	PROPN
american_scientific_journal-4355	115	4	-	-	PUNCT
american_scientific_journal-4355	115	5	β	β	NOUN
american_scientific_journal-4355	115	6	signalling	signal	VERB
american_scientific_journal-4355	115	7	in	in	ADP
american_scientific_journal-4355	115	8	a	a	DET
american_scientific_journal-4355	115	9	ligand	ligand	ADJ
american_scientific_journal-4355	115	10	-	-	PUNCT
american_scientific_journal-4355	115	11	independent	independent	ADJ
american_scientific_journal-4355	115	12	manner	manner	NOUN
american_scientific_journal-4355	115	13	,	,	PUNCT
american_scientific_journal-4355	115	14	through	through	ADP
american_scientific_journal-4355	115	15	activation	activation	NOUN
american_scientific_journal-4355	115	16	of	of	ADP
american_scientific_journal-4355	115	17	the	the	DET
american_scientific_journal-4355	115	18	p38	p38	NOUN
american_scientific_journal-4355	115	19	pathway	pathway	NOUN
american_scientific_journal-4355	115	20	)	)	PUNCT
american_scientific_journal-4355	115	21	.	.	PUNCT
american_scientific_journal-4355	116	1	2.4	2.4	NUM
american_scientific_journal-4355	116	2	.	.	PUNCT
american_scientific_journal-4355	117	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	117	2	and	and	CCONJ
american_scientific_journal-4355	117	3	renal	renal	ADJ
american_scientific_journal-4355	117	4	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	117	5	transforming	transform	VERB
american_scientific_journal-4355	117	6	growth	growth	NOUN
american_scientific_journal-4355	117	7	factor	factor	NOUN
american_scientific_journal-4355	117	8	-	-	PUNCT
american_scientific_journal-4355	117	9	β	β	X
american_scientific_journal-4355	117	10	(	(	PUNCT
american_scientific_journal-4355	117	11	tgf	tgf	PROPN
american_scientific_journal-4355	117	12	-	-	PUNCT
american_scientific_journal-4355	117	13	β	β	NOUN
american_scientific_journal-4355	117	14	)	)	PUNCT
american_scientific_journal-4355	117	15	is	be	AUX
american_scientific_journal-4355	117	16	a	a	DET
american_scientific_journal-4355	117	17	key	key	ADJ
american_scientific_journal-4355	117	18	mediator	mediator	NOUN
american_scientific_journal-4355	117	19	in	in	ADP
american_scientific_journal-4355	117	20	the	the	DET
american_scientific_journal-4355	117	21	pathogenesis	pathogenesis	NOUN
american_scientific_journal-4355	117	22	of	of	ADP
american_scientific_journal-4355	117	23	renal	renal	ADJ
american_scientific_journal-4355	117	24	diseases	disease	NOUN
american_scientific_journal-4355	117	25	.	.	PUNCT
american_scientific_journal-4355	118	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	118	2	,	,	PUNCT
american_scientific_journal-4355	118	3	which	which	PRON
american_scientific_journal-4355	118	4	is	be	AUX
american_scientific_journal-4355	118	5	a	a	DET
american_scientific_journal-4355	118	6	type	type	NOUN
american_scientific_journal-4355	118	7	iii	iii	NUM
american_scientific_journal-4355	118	8	tgf	tgf	PROPN
american_scientific_journal-4355	118	9	-	-	PUNCT
american_scientific_journal-4355	118	10	β	β	NOUN
american_scientific_journal-4355	118	11	receptor	receptor	NOUN
american_scientific_journal-4355	118	12	and	and	CCONJ
american_scientific_journal-4355	118	13	regulates	regulate	VERB
american_scientific_journal-4355	118	14	tgf	tgf	PROPN
american_scientific_journal-4355	118	15	-	-	PUNCT
american_scientific_journal-4355	118	16	β	β	PROPN
american_scientific_journal-4355	118	17	action	action	NOUN
american_scientific_journal-4355	118	18	by	by	ADP
american_scientific_journal-4355	118	19	modulating	modulate	VERB
american_scientific_journal-4355	118	20	its	its	PRON
american_scientific_journal-4355	118	21	access	access	NOUN
american_scientific_journal-4355	118	22	to	to	ADP
american_scientific_journal-4355	118	23	the	the	DET
american_scientific_journal-4355	118	24	type	type	NOUN
american_scientific_journal-4355	118	25	i	i	PROPN
american_scientific_journal-4355	118	26	and	and	CCONJ
american_scientific_journal-4355	118	27	ii	ii	NOUN
american_scientific_journal-4355	118	28	receptors	receptor	NOUN
american_scientific_journal-4355	118	29	.	.	PUNCT
american_scientific_journal-4355	119	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	119	2	potentiates	potentiate	VERB
american_scientific_journal-4355	119	3	tgf	tgf	PROPN
american_scientific_journal-4355	119	4	-	-	PUNCT
american_scientific_journal-4355	119	5	β	β	PROPN
american_scientific_journal-4355	119	6	;	;	PUNCT
american_scientific_journal-4355	119	7	however	however	ADV
american_scientific_journal-4355	119	8	,	,	PUNCT
american_scientific_journal-4355	119	9	soluble	soluble	ADJ
american_scientific_journal-4355	119	10	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	119	11	,	,	PUNCT
american_scientific_journal-4355	119	12	which	which	PRON
american_scientific_journal-4355	119	13	is	be	AUX
american_scientific_journal-4355	119	14	produced	produce	VERB
american_scientific_journal-4355	119	15	by	by	ADP
american_scientific_journal-4355	119	16	the	the	DET
american_scientific_journal-4355	119	17	shedding	shedding	NOUN
american_scientific_journal-4355	119	18	of	of	ADP
american_scientific_journal-4355	119	19	the	the	DET
american_scientific_journal-4355	119	20	membrane	membrane	NOUN
american_scientific_journal-4355	119	21	-	-	PUNCT
american_scientific_journal-4355	119	22	bound	bind	VERB
american_scientific_journal-4355	119	23	receptor	receptor	NOUN
american_scientific_journal-4355	119	24	,	,	PUNCT
american_scientific_journal-4355	119	25	is	be	AUX
american_scientific_journal-4355	119	26	a	a	DET
american_scientific_journal-4355	119	27	potent	potent	ADJ
american_scientific_journal-4355	119	28	antagonist	antagonist	NOUN
american_scientific_journal-4355	119	29	of	of	ADP
american_scientific_journal-4355	119	30	tgf	tgf	PROPN
american_scientific_journal-4355	119	31	-	-	PUNCT
american_scientific_journal-4355	119	32	β	β	NOUN
american_scientific_journal-4355	119	33	.	.	PUNCT
american_scientific_journal-4355	120	1	this	this	PRON
american_scientific_journal-4355	120	2	was	be	AUX
american_scientific_journal-4355	120	3	documented	document	VERB
american_scientific_journal-4355	120	4	to	to	PART
american_scientific_journal-4355	120	5	prevent	prevent	VERB
american_scientific_journal-4355	120	6	renal	renal	ADJ
american_scientific_journal-4355	120	7	damage	damage	NOUN
american_scientific_journal-4355	120	8	in	in	ADP
american_scientific_journal-4355	120	9	genetically	genetically	ADV
american_scientific_journal-4355	120	10	obese	obese	ADJ
american_scientific_journal-4355	120	11	and	and	CCONJ
american_scientific_journal-4355	120	12	diabetic	diabetic	ADJ
american_scientific_journal-4355	120	13	db	db	PROPN
american_scientific_journal-4355	120	14	/	/	SYM
american_scientific_journal-4355	120	15	db	db	NOUN
american_scientific_journal-4355	120	16	mice	mouse	NOUN
american_scientific_journal-4355	120	17	,	,	PUNCT
american_scientific_journal-4355	120	18	because	because	SCONJ
american_scientific_journal-4355	120	19	sbg	sbg	PROPN
american_scientific_journal-4355	120	20	(	(	PUNCT
american_scientific_journal-4355	120	21	soluble	soluble	ADJ
american_scientific_journal-4355	120	22	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	120	23	)	)	PUNCT
american_scientific_journal-4355	120	24	has	have	VERB
american_scientific_journal-4355	120	25	a	a	DET
american_scientific_journal-4355	120	26	high	high	ADJ
american_scientific_journal-4355	120	27	affinity	affinity	NOUN
american_scientific_journal-4355	120	28	for	for	ADP
american_scientific_journal-4355	120	29	all	all	DET
american_scientific_journal-4355	120	30	tgf	tgf	PROPN
american_scientific_journal-4355	120	31	-	-	PUNCT
american_scientific_journal-4355	120	32	β	β	NOUN
american_scientific_journal-4355	120	33	isoforms	isoform	NOUN
american_scientific_journal-4355	120	34	,	,	PUNCT
american_scientific_journal-4355	120	35	in	in	ADP
american_scientific_journal-4355	120	36	particular	particular	ADJ
american_scientific_journal-4355	120	37	tgf	tgf	PROPN
american_scientific_journal-4355	120	38	-	-	PUNCT
american_scientific_journal-4355	120	39	β2	β2	PROPN
american_scientific_journal-4355	120	40	,	,	PUNCT
american_scientific_journal-4355	120	41	it	it	PRON
american_scientific_journal-4355	120	42	is	be	AUX
american_scientific_journal-4355	120	43	found	find	VERB
american_scientific_journal-4355	120	44	naturally	naturally	ADV
american_scientific_journal-4355	120	45	in	in	ADP
american_scientific_journal-4355	120	46	serum	serum	NOUN
american_scientific_journal-4355	120	47	and	and	CCONJ
american_scientific_journal-4355	120	48	tissues	tissue	NOUN
american_scientific_journal-4355	120	49	and	and	CCONJ
american_scientific_journal-4355	120	50	its	its	PRON
american_scientific_journal-4355	120	51	shedding	shedding	NOUN
american_scientific_journal-4355	120	52	may	may	AUX
american_scientific_journal-4355	120	53	be	be	AUX
american_scientific_journal-4355	120	54	regulated	regulate	VERB
american_scientific_journal-4355	120	55	.	.	PUNCT
american_scientific_journal-4355	121	1	it	it	PRON
american_scientific_journal-4355	121	2	is	be	AUX
american_scientific_journal-4355	121	3	believed	believe	VERB
american_scientific_journal-4355	121	4	that	that	SCONJ
american_scientific_journal-4355	121	5	sbg	sbg	NOUN
american_scientific_journal-4355	121	6	will	will	AUX
american_scientific_journal-4355	121	7	prove	prove	VERB
american_scientific_journal-4355	121	8	convenient	convenient	ADJ
american_scientific_journal-4355	121	9	for	for	ADP
american_scientific_journal-4355	121	10	long	long	ADJ
american_scientific_journal-4355	121	11	-	-	PUNCT
american_scientific_journal-4355	121	12	term	term	NOUN
american_scientific_journal-4355	121	13	treatment	treatment	NOUN
american_scientific_journal-4355	121	14	of	of	ADP
american_scientific_journal-4355	121	15	kidney	kidney	NOUN
american_scientific_journal-4355	121	16	diseases	disease	NOUN
american_scientific_journal-4355	121	17	and	and	CCONJ
american_scientific_journal-4355	121	18	other	other	ADJ
american_scientific_journal-4355	121	19	pathologies	pathology	NOUN
american_scientific_journal-4355	121	20	in	in	ADP
american_scientific_journal-4355	121	21	which	which	PRON
american_scientific_journal-4355	121	22	tgf	tgf	PROPN
american_scientific_journal-4355	121	23	-	-	PUNCT
american_scientific_journal-4355	121	24	β	β	PROPN
american_scientific_journal-4355	121	25	plays	play	VERB
american_scientific_journal-4355	121	26	a	a	DET
american_scientific_journal-4355	121	27	pathophysiological	pathophysiological	ADJ
american_scientific_journal-4355	121	28	role	role	NOUN
american_scientific_journal-4355	121	29	,	,	PUNCT
american_scientific_journal-4355	121	30	as	as	SCONJ
american_scientific_journal-4355	121	31	it	it	PRON
american_scientific_journal-4355	121	32	occurs	occur	VERB
american_scientific_journal-4355	121	33	as	as	ADP
american_scientific_journal-4355	121	34	a	a	DET
american_scientific_journal-4355	121	35	proteoglycan	proteoglycan	ADJ
american_scientific_journal-4355	121	36	heparan	heparan	ADJ
american_scientific_journal-4355	121	37	sulfate	sulfate	NOUN
american_scientific_journal-4355	121	38	(	(	PUNCT
american_scientific_journal-4355	121	39	hs	hs	X
american_scientific_journal-4355	121	40	)	)	PUNCT
american_scientific_journal-4355	121	41	which	which	PRON
american_scientific_journal-4355	121	42	is	be	AUX
american_scientific_journal-4355	121	43	a	a	DET
american_scientific_journal-4355	121	44	linear	linear	ADJ
american_scientific_journal-4355	121	45	polysaccharide	polysaccharide	NOUN
american_scientific_journal-4355	121	46	found	find	VERB
american_scientific_journal-4355	121	47	in	in	ADP
american_scientific_journal-4355	121	48	all	all	DET
american_scientific_journal-4355	121	49	animal	animal	NOUN
american_scientific_journal-4355	121	50	tissues	tissue	NOUN
american_scientific_journal-4355	121	51	.	.	PUNCT
american_scientific_journal-4355	122	1	it	it	PRON
american_scientific_journal-4355	122	2	occurs	occur	VERB
american_scientific_journal-4355	122	3	as	as	ADP
american_scientific_journal-4355	122	4	a	a	DET
american_scientific_journal-4355	122	5	pg	pg	NOUN
american_scientific_journal-4355	122	6	in	in	ADP
american_scientific_journal-4355	122	7	which	which	PRON
american_scientific_journal-4355	122	8	two	two	NUM
american_scientific_journal-4355	122	9	or	or	CCONJ
american_scientific_journal-4355	122	10	three	three	NUM
american_scientific_journal-4355	122	11	hs	hs	PROPN
american_scientific_journal-4355	122	12	chains	chain	NOUN
american_scientific_journal-4355	122	13	are	be	AUX
american_scientific_journal-4355	122	14	attached	attach	VERB
american_scientific_journal-4355	122	15	in	in	ADP
american_scientific_journal-4355	122	16	close	close	ADJ
american_scientific_journal-4355	122	17	proximity	proximity	NOUN
american_scientific_journal-4355	122	18	to	to	ADP
american_scientific_journal-4355	122	19	cell	cell	NOUN
american_scientific_journal-4355	122	20	surface	surface	NOUN
american_scientific_journal-4355	122	21	or	or	CCONJ
american_scientific_journal-4355	122	22	extracellular	extracellular	ADJ
american_scientific_journal-4355	122	23	matrix	matrix	NOUN
american_scientific_journal-4355	122	24	proteins[23	proteins[23	NOUN
american_scientific_journal-4355	122	25	]	]	PUNCT
american_scientific_journal-4355	122	26	.	.	PUNCT
american_scientific_journal-4355	123	1	the	the	DET
american_scientific_journal-4355	123	2	major	major	ADJ
american_scientific_journal-4355	123	3	cell	cell	NOUN
american_scientific_journal-4355	123	4	membrane	membrane	NOUN
american_scientific_journal-4355	123	5	hspgs	hspgs	NOUN
american_scientific_journal-4355	123	6	are	be	AUX
american_scientific_journal-4355	123	7	the	the	DET
american_scientific_journal-4355	123	8	transmembrane	transmembrane	ADJ
american_scientific_journal-4355	123	9	syndecans	syndecan	NOUN
american_scientific_journal-4355	123	10	(	(	PUNCT
american_scientific_journal-4355	123	11	gpi	gpi	PROPN
american_scientific_journal-4355	123	12	)	)	PUNCT
american_scientific_journal-4355	123	13	anchored	anchor	VERB
american_scientific_journal-4355	123	14	glypicans	glypican	NOUN
american_scientific_journal-4355	123	15	.	.	PUNCT
american_scientific_journal-4355	124	1	other	other	ADJ
american_scientific_journal-4355	124	2	forms	form	NOUN
american_scientific_journal-4355	124	3	of	of	ADP
american_scientific_journal-4355	124	4	membrane	membrane	NOUN
american_scientific_journal-4355	124	5	hspg	hspg	NOUN
american_scientific_journal-4355	124	6	include	include	VERB
american_scientific_journal-4355	124	7	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	124	8	and	and	CCONJ
american_scientific_journal-4355	124	9	the	the	DET
american_scientific_journal-4355	124	10	glycosylphosphatidylinositol	glycosylphosphatidylinositol	NOUN
american_scientific_journal-4355	125	1	[	[	X
american_scientific_journal-4355	125	2	24	24	NUM
american_scientific_journal-4355	125	3	]	]	PUNCT
american_scientific_journal-4355	125	4	.	.	PUNCT
american_scientific_journal-4355	126	1	in	in	ADP
american_scientific_journal-4355	126	2	contrast	contrast	NOUN
american_scientific_journal-4355	126	3	to	to	ADP
american_scientific_journal-4355	126	4	membrane	membrane	NOUN
american_scientific_journal-4355	126	5	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	126	6	,	,	PUNCT
american_scientific_journal-4355	126	7	sbg	sbg	PROPN
american_scientific_journal-4355	126	8	inhibits	inhibit	VERB
american_scientific_journal-4355	126	9	tgf	tgf	PROPN
american_scientific_journal-4355	126	10	-	-	PUNCT
american_scientific_journal-4355	126	11	β	β	NOUN
american_scientific_journal-4355	126	12	binding	bind	VERB
american_scientific_journal-4355	126	13	to	to	ADP
american_scientific_journal-4355	126	14	kinase	kinase	NOUN
american_scientific_journal-4355	126	15	receptors	receptor	NOUN
american_scientific_journal-4355	126	16	and	and	CCONJ
american_scientific_journal-4355	126	17	thereby	thereby	ADV
american_scientific_journal-4355	126	18	works	work	VERB
american_scientific_journal-4355	126	19	as	as	ADP
american_scientific_journal-4355	126	20	a	a	DET
american_scientific_journal-4355	126	21	tgf	tgf	PROPN
american_scientific_journal-4355	126	22	-	-	PUNCT
american_scientific_journal-4355	126	23	β	β	NOUN
american_scientific_journal-4355	126	24	antagonist	antagonist	NOUN
american_scientific_journal-4355	126	25	[	[	X
american_scientific_journal-4355	126	26	25	25	NUM
american_scientific_journal-4355	126	27	]	]	PUNCT
american_scientific_journal-4355	126	28	.	.	PUNCT
american_scientific_journal-4355	127	1	the	the	DET
american_scientific_journal-4355	127	2	administration	administration	NOUN
american_scientific_journal-4355	127	3	of	of	ADP
american_scientific_journal-4355	127	4	sbg	sbg	PROPN
american_scientific_journal-4355	127	5	to	to	PART
american_scientific_journal-4355	127	6	db	db	VERB
american_scientific_journal-4355	127	7	/	/	SYM
american_scientific_journal-4355	127	8	db	db	PROPN
american_scientific_journal-4355	127	9	mice	mouse	NOUN
american_scientific_journal-4355	127	10	,	,	PUNCT
american_scientific_journal-4355	127	11	resulted	result	VERB
american_scientific_journal-4355	127	12	in	in	ADP
american_scientific_journal-4355	127	13	a	a	DET
american_scientific_journal-4355	127	14	reduction	reduction	NOUN
american_scientific_journal-4355	127	15	in	in	ADP
american_scientific_journal-4355	127	16	kidney	kidney	NOUN
american_scientific_journal-4355	127	17	damage	damage	NOUN
american_scientific_journal-4355	127	18	,	,	PUNCT
american_scientific_journal-4355	127	19	plasma	plasma	NOUN
american_scientific_journal-4355	127	20	creatinine	creatinine	NOUN
american_scientific_journal-4355	127	21	concentration	concentration	NOUN
american_scientific_journal-4355	127	22	,	,	PUNCT
american_scientific_journal-4355	127	23	albuminuria	albuminuria	NOUN
american_scientific_journal-4355	127	24	,	,	PUNCT
american_scientific_journal-4355	127	25	and	and	CCONJ
american_scientific_journal-4355	127	26	mesangial	mesangial	ADJ
american_scientific_journal-4355	127	27	matrix	matrix	NOUN
american_scientific_journal-4355	127	28	expansion	expansion	NOUN
american_scientific_journal-4355	127	29	,	,	PUNCT
american_scientific_journal-4355	127	30	[	[	X
american_scientific_journal-4355	127	31	26	26	NUM
american_scientific_journal-4355	127	32	]	]	PUNCT
american_scientific_journal-4355	127	33	,	,	PUNCT
american_scientific_journal-4355	127	34	were	be	AUX
american_scientific_journal-4355	127	35	significantly	significantly	ADV
american_scientific_journal-4355	127	36	reduced	reduce	VERB
american_scientific_journal-4355	127	37	by	by	ADP
american_scientific_journal-4355	127	38	the	the	DET
american_scientific_journal-4355	127	39	treatment	treatment	NOUN
american_scientific_journal-4355	127	40	with	with	ADP
american_scientific_journal-4355	127	41	sbg	sbg	NOUN
american_scientific_journal-4355	127	42	,	,	PUNCT
american_scientific_journal-4355	127	43	so	so	SCONJ
american_scientific_journal-4355	127	44	it	it	PRON
american_scientific_journal-4355	127	45	has	have	AUX
american_scientific_journal-4355	127	46	been	be	AUX
american_scientific_journal-4355	127	47	shown	show	VERB
american_scientific_journal-4355	127	48	that	that	SCONJ
american_scientific_journal-4355	127	49	sbg	sbg	NOUN
american_scientific_journal-4355	127	50	treatment	treatment	NOUN
american_scientific_journal-4355	127	51	of	of	ADP
american_scientific_journal-4355	127	52	db	db	PROPN
american_scientific_journal-4355	127	53	/	/	SYM
american_scientific_journal-4355	127	54	db	db	PROPN
american_scientific_journal-4355	127	55	mice	mouse	NOUN
american_scientific_journal-4355	127	56	significantly	significantly	ADV
american_scientific_journal-4355	127	57	ameliorates	ameliorate	VERB
american_scientific_journal-4355	127	58	the	the	DET
american_scientific_journal-4355	127	59	progression	progression	NOUN
american_scientific_journal-4355	127	60	of	of	ADP
american_scientific_journal-4355	127	61	kidney	kidney	NOUN
american_scientific_journal-4355	127	62	dysfunction	dysfunction	NOUN
american_scientific_journal-4355	127	63	,	,	PUNCT
american_scientific_journal-4355	127	64	without	without	ADP
american_scientific_journal-4355	127	65	any	any	DET
american_scientific_journal-4355	127	66	apparent	apparent	ADJ
american_scientific_journal-4355	127	67	negative	negative	ADJ
american_scientific_journal-4355	127	68	side	side	NOUN
american_scientific_journal-4355	127	69	effect	effect	NOUN
american_scientific_journal-4355	127	70	,	,	PUNCT
american_scientific_journal-4355	127	71	as	as	SCONJ
american_scientific_journal-4355	127	72	indicated	indicate	VERB
american_scientific_journal-4355	127	73	by	by	ADP
american_scientific_journal-4355	127	74	the	the	DET
american_scientific_journal-4355	127	75	absence	absence	NOUN
american_scientific_journal-4355	127	76	of	of	ADP
american_scientific_journal-4355	127	77	gross	gross	ADJ
american_scientific_journal-4355	127	78	macroscopic	macroscopic	ADJ
american_scientific_journal-4355	127	79	damage	damage	NOUN
american_scientific_journal-4355	127	80	of	of	ADP
american_scientific_journal-4355	127	81	internal	internal	ADJ
american_scientific_journal-4355	127	82	organs[27	organs[27	PROPN
american_scientific_journal-4355	127	83	]	]	PUNCT
american_scientific_journal-4355	127	84	.	.	PUNCT
american_scientific_journal-4355	128	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	128	2	(	(	PUNCT
american_scientific_journal-4355	128	3	bg	bg	PROPN
american_scientific_journal-4355	128	4	)	)	PUNCT
american_scientific_journal-4355	128	5	has	have	VERB
american_scientific_journal-4355	128	6	a	a	DET
american_scientific_journal-4355	128	7	dual	dual	ADJ
american_scientific_journal-4355	128	8	role	role	NOUN
american_scientific_journal-4355	128	9	in	in	ADP
american_scientific_journal-4355	128	10	the	the	DET
american_scientific_journal-4355	128	11	modulation	modulation	NOUN
american_scientific_journal-4355	128	12	of	of	ADP
american_scientific_journal-4355	128	13	tgf	tgf	PROPN
american_scientific_journal-4355	128	14	-	-	PUNCT
american_scientific_journal-4355	128	15	β	β	NOUN
american_scientific_journal-4355	128	16	activities	activity	NOUN
american_scientific_journal-4355	128	17	(	(	PUNCT
american_scientific_journal-4355	128	18	figure	figure	NOUN
american_scientific_journal-4355	128	19	4	4	NUM
american_scientific_journal-4355	128	20	)	)	PUNCT
american_scientific_journal-4355	128	21	.	.	PUNCT
american_scientific_journal-4355	129	1	bg	bg	PROPN
american_scientific_journal-4355	129	2	,	,	PUNCT
american_scientific_journal-4355	129	3	potentiates	potentiate	VERB
american_scientific_journal-4355	129	4	tgf	tgf	PROPN
american_scientific_journal-4355	129	5	-	-	PUNCT
american_scientific_journal-4355	129	6	β	β	NOUN
american_scientific_journal-4355	129	7	actions	action	NOUN
american_scientific_journal-4355	129	8	when	when	SCONJ
american_scientific_journal-4355	129	9	it	it	PRON
american_scientific_journal-4355	129	10	is	be	AUX
american_scientific_journal-4355	129	11	membrane	membrane	NOUN
american_scientific_journal-4355	129	12	bound	bind	VERB
american_scientific_journal-4355	129	13	.	.	PUNCT
american_scientific_journal-4355	130	1	shedding	shed	VERB
american_scientific_journal-4355	130	2	of	of	ADP
american_scientific_journal-4355	130	3	bg	bg	PROPN
american_scientific_journal-4355	130	4	extracellular	extracellular	ADJ
american_scientific_journal-4355	130	5	region	region	NOUN
american_scientific_journal-4355	130	6	generates	generate	VERB
american_scientific_journal-4355	130	7	the	the	DET
american_scientific_journal-4355	130	8	soluble	soluble	ADJ
american_scientific_journal-4355	130	9	form	form	NOUN
american_scientific_journal-4355	130	10	of	of	ADP
american_scientific_journal-4355	130	11	the	the	DET
american_scientific_journal-4355	130	12	receptor	receptor	NOUN
american_scientific_journal-4355	130	13	.	.	PUNCT
american_scientific_journal-4355	131	1	soluble	soluble	ADJ
american_scientific_journal-4355	131	2	bg	bg	PROPN
american_scientific_journal-4355	131	3	still	still	ADV
american_scientific_journal-4355	131	4	binds	bind	VERB
american_scientific_journal-4355	131	5	tgf	tgf	PROPN
american_scientific_journal-4355	131	6	-	-	PUNCT
american_scientific_journal-4355	131	7	β	β	PROPN
american_scientific_journal-4355	131	8	with	with	ADP
american_scientific_journal-4355	131	9	the	the	DET
american_scientific_journal-4355	131	10	high	high	ADJ
american_scientific_journal-4355	131	11	affinity	affinity	NOUN
american_scientific_journal-4355	131	12	of	of	ADP
american_scientific_journal-4355	131	13	the	the	DET
american_scientific_journal-4355	131	14	membrane	membrane	NOUN
american_scientific_journal-4355	131	15	bg	bg	PROPN
american_scientific_journal-4355	131	16	,	,	PUNCT
american_scientific_journal-4355	131	17	but	but	CCONJ
american_scientific_journal-4355	131	18	instead	instead	ADV
american_scientific_journal-4355	131	19	of	of	ADP
american_scientific_journal-4355	131	20	presenting	present	VERB
american_scientific_journal-4355	131	21	it	it	PRON
american_scientific_journal-4355	131	22	to	to	ADP
american_scientific_journal-4355	131	23	the	the	DET
american_scientific_journal-4355	131	24	type	type	NOUN
american_scientific_journal-4355	131	25	ii	ii	NOUN
american_scientific_journal-4355	131	26	receptor	receptor	NOUN
american_scientific_journal-4355	131	27	,	,	PUNCT
american_scientific_journal-4355	131	28	soluble	soluble	ADJ
american_scientific_journal-4355	131	29	bg	bg	PROPN
american_scientific_journal-4355	131	30	sequesters	sequester	VERB
american_scientific_journal-4355	131	31	it	it	PRON
american_scientific_journal-4355	131	32	and	and	CCONJ
american_scientific_journal-4355	131	33	thus	thus	ADV
american_scientific_journal-4355	131	34	neutralizes	neutralize	VERB
american_scientific_journal-4355	131	35	its	its	PRON
american_scientific_journal-4355	131	36	actions[28	actions[28	NOUN
american_scientific_journal-4355	131	37	]	]	PUNCT
american_scientific_journal-4355	131	38	.	.	PUNCT
american_scientific_journal-4355	132	1	unique	unique	ADJ
american_scientific_journal-4355	132	2	among	among	ADP
american_scientific_journal-4355	132	3	other	other	ADJ
american_scientific_journal-4355	132	4	tgf	tgf	PROPN
american_scientific_journal-4355	132	5	-	-	PUNCT
american_scientific_journal-4355	132	6	β	β	NOUN
american_scientific_journal-4355	132	7	inhibitors	inhibitor	NOUN
american_scientific_journal-4355	132	8	is	be	AUX
american_scientific_journal-4355	132	9	the	the	DET
american_scientific_journal-4355	132	10	fact	fact	NOUN
american_scientific_journal-4355	132	11	that	that	SCONJ
american_scientific_journal-4355	132	12	bg	bg	PROPN
american_scientific_journal-4355	132	13	may	may	AUX
american_scientific_journal-4355	132	14	be	be	AUX
american_scientific_journal-4355	132	15	subject	subject	ADJ
american_scientific_journal-4355	132	16	to	to	ADP
american_scientific_journal-4355	132	17	regulated	regulated	ADJ
american_scientific_journal-4355	132	18	shedding	shedding	NOUN
american_scientific_journal-4355	132	19	of	of	ADP
american_scientific_journal-4355	132	20	its	its	PRON
american_scientific_journal-4355	132	21	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	132	22	[	[	X
american_scientific_journal-4355	132	23	29	29	NUM
american_scientific_journal-4355	132	24	]	]	PUNCT
american_scientific_journal-4355	132	25	,	,	PUNCT
american_scientific_journal-4355	132	26	making	make	VERB
american_scientific_journal-4355	132	27	possible	possible	ADJ
american_scientific_journal-4355	132	28	,	,	PUNCT
american_scientific_journal-4355	132	29	in	in	ADP
american_scientific_journal-4355	132	30	principle	principle	NOUN
american_scientific_journal-4355	132	31	,	,	PUNCT
american_scientific_journal-4355	132	32	control	control	NOUN
american_scientific_journal-4355	132	33	of	of	ADP
american_scientific_journal-4355	132	34	the	the	DET
american_scientific_journal-4355	132	35	relative	relative	ADJ
american_scientific_journal-4355	132	36	ratio	ratio	NOUN
american_scientific_journal-4355	132	37	of	of	ADP
american_scientific_journal-4355	132	38	the	the	DET
american_scientific_journal-4355	132	39	membrane	membrane	NOUN
american_scientific_journal-4355	132	40	and	and	CCONJ
american_scientific_journal-4355	132	41	soluble	soluble	ADJ
american_scientific_journal-4355	132	42	forms	form	NOUN
american_scientific_journal-4355	132	43	of	of	ADP
american_scientific_journal-4355	132	44	the	the	DET
american_scientific_journal-4355	132	45	receptor	receptor	NOUN
american_scientific_journal-4355	132	46	,	,	PUNCT
american_scientific_journal-4355	132	47	providing	provide	VERB
american_scientific_journal-4355	132	48	a	a	DET
american_scientific_journal-4355	132	49	way	way	NOUN
american_scientific_journal-4355	132	50	to	to	PART
american_scientific_journal-4355	132	51	switch	switch	VERB
american_scientific_journal-4355	132	52	tgf	tgf	PROPN
american_scientific_journal-4355	132	53	-	-	PUNCT
american_scientific_journal-4355	132	54	β	β	PROPN
american_scientific_journal-4355	132	55	actions	action	NOUN
american_scientific_journal-4355	132	56	on	on	ADP
american_scientific_journal-4355	132	57	or	or	CCONJ
american_scientific_journal-4355	132	58	off	off	ADV
american_scientific_journal-4355	132	59	.	.	PUNCT
american_scientific_journal-4355	133	1	sbg	sbg	PROPN
american_scientific_journal-4355	133	2	is	be	AUX
american_scientific_journal-4355	133	3	a	a	DET
american_scientific_journal-4355	133	4	renoprotective	renoprotective	ADJ
american_scientific_journal-4355	133	5	agent	agent	NOUN
american_scientific_journal-4355	133	6	that	that	PRON
american_scientific_journal-4355	133	7	neutralized	neutralize	VERB
american_scientific_journal-4355	133	8	tgf	tgf	PROPN
american_scientific_journal-4355	133	9	-	-	PUNCT
american_scientific_journal-4355	133	10	β	β	PROPN
american_scientific_journal-4355	133	11	actions	action	NOUN
american_scientific_journal-4355	133	12	in	in	ADP
american_scientific_journal-4355	133	13	this	this	DET
american_scientific_journal-4355	133	14	model	model	NOUN
american_scientific_journal-4355	133	15	of	of	ADP
american_scientific_journal-4355	133	16	nephropathy	nephropathy	NOUN
american_scientific_journal-4355	133	17	.	.	PUNCT
american_scientific_journal-4355	134	1	because	because	SCONJ
american_scientific_journal-4355	134	2	sbg	sbg	PROPN
american_scientific_journal-4355	134	3	has	have	VERB
american_scientific_journal-4355	134	4	a	a	DET
american_scientific_journal-4355	134	5	high	high	ADJ
american_scientific_journal-4355	134	6	affinity	affinity	NOUN
american_scientific_journal-4355	134	7	for	for	ADP
american_scientific_journal-4355	134	8	all	all	DET
american_scientific_journal-4355	134	9	tgfisoforms	tgfisoform	NOUN
american_scientific_journal-4355	134	10	,	,	PUNCT
american_scientific_journal-4355	134	11	in	in	ADP
american_scientific_journal-4355	134	12	particular	particular	ADJ
american_scientific_journal-4355	134	13	tgf	tgf	PROPN
american_scientific_journal-4355	134	14	-	-	PUNCT
american_scientific_journal-4355	134	15	β	β	PROPN
american_scientific_journal-4355	134	16	2	2	NUM
american_scientific_journal-4355	134	17	,	,	PUNCT
american_scientific_journal-4355	134	18	it	it	PRON
american_scientific_journal-4355	134	19	is	be	AUX
american_scientific_journal-4355	134	20	found	find	VERB
american_scientific_journal-4355	134	21	naturally	naturally	ADV
american_scientific_journal-4355	134	22	in	in	ADP
american_scientific_journal-4355	134	23	serum	serum	NOUN
american_scientific_journal-4355	134	24	and	and	CCONJ
american_scientific_journal-4355	134	25	tissues	tissue	NOUN
american_scientific_journal-4355	134	26	and	and	CCONJ
american_scientific_journal-4355	134	27	its	its	PRON
american_scientific_journal-4355	134	28	shedding	shedding	NOUN
american_scientific_journal-4355	134	29	may	may	AUX
american_scientific_journal-4355	134	30	be	be	AUX
american_scientific_journal-4355	134	31	regulated	regulate	VERB
american_scientific_journal-4355	134	32	.	.	PUNCT
american_scientific_journal-4355	135	1	we	we	PRON
american_scientific_journal-4355	135	2	believe	believe	VERB
american_scientific_journal-4355	135	3	that	that	SCONJ
american_scientific_journal-4355	135	4	sbg	sbg	NOUN
american_scientific_journal-4355	135	5	will	will	AUX
american_scientific_journal-4355	135	6	prove	prove	VERB
american_scientific_journal-4355	135	7	convenient	convenient	ADJ
american_scientific_journal-4355	135	8	for	for	ADP
american_scientific_journal-4355	135	9	long	long	ADJ
american_scientific_journal-4355	135	10	-	-	PUNCT
american_scientific_journal-4355	135	11	term	term	NOUN
american_scientific_journal-4355	135	12	treatment	treatment	NOUN
american_scientific_journal-4355	135	13	of	of	ADP
american_scientific_journal-4355	135	14	kidney	kidney	NOUN
american_scientific_journal-4355	135	15	diseases	disease	NOUN
american_scientific_journal-4355	135	16	and	and	CCONJ
american_scientific_journal-4355	135	17	other	other	ADJ
american_scientific_journal-4355	135	18	pathologies	pathology	NOUN
american_scientific_journal-4355	135	19	in	in	ADP
american_scientific_journal-4355	135	20	which	which	PRON
american_scientific_journal-4355	135	21	tgfplays	tgfplay	VERB
american_scientific_journal-4355	135	22	a	a	DET
american_scientific_journal-4355	135	23	pathophysiological	pathophysiological	ADJ
american_scientific_journal-4355	135	24	role	role	NOUN
american_scientific_journal-4355	135	25	[	[	X
american_scientific_journal-4355	135	26	30	30	NUM
american_scientific_journal-4355	135	27	]	]	PUNCT
american_scientific_journal-4355	135	28	.	.	PUNCT
american_scientific_journal-4355	136	1	as	as	ADP
american_scientific_journal-4355	136	2	inerstitial	inerstitial	ADJ
american_scientific_journal-4355	136	3	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	136	4	,	,	PUNCT
american_scientific_journal-4355	136	5	related	relate	VERB
american_scientific_journal-4355	136	6	to	to	ADP
american_scientific_journal-4355	136	7	accumulation	accumulation	NOUN
american_scientific_journal-4355	136	8	of	of	ADP
american_scientific_journal-4355	136	9	ecm	ecm	NOUN
american_scientific_journal-4355	136	10	,	,	PUNCT
american_scientific_journal-4355	136	11	it	it	PRON
american_scientific_journal-4355	136	12	also	also	ADV
american_scientific_journal-4355	136	13	related	relate	VERB
american_scientific_journal-4355	136	14	to	to	ADP
american_scientific_journal-4355	136	15	progression	progression	NOUN
american_scientific_journal-4355	136	16	of	of	ADP
american_scientific_journal-4355	136	17	renal	renal	ADJ
american_scientific_journal-4355	136	18	disease	disease	NOUN
american_scientific_journal-4355	136	19	with	with	ADP
american_scientific_journal-4355	136	20	accumulation	accumulation	NOUN
american_scientific_journal-4355	136	21	of	of	ADP
american_scientific_journal-4355	136	22	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	136	23	and	and	CCONJ
american_scientific_journal-4355	136	24	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	136	25	which	which	PRON
american_scientific_journal-4355	136	26	is	be	AUX
american_scientific_journal-4355	136	27	related	relate	VERB
american_scientific_journal-4355	136	28	to	to	PART
american_scientific_journal-4355	136	29	nephron	nephron	VERB
american_scientific_journal-4355	136	30	loss	loss	NOUN
american_scientific_journal-4355	136	31	and	and	CCONJ
american_scientific_journal-4355	136	32	kidney	kidney	NOUN
american_scientific_journal-4355	136	33	shut	shut	VERB
american_scientific_journal-4355	136	34	down	down	ADP
american_scientific_journal-4355	136	35	,	,	PUNCT
american_scientific_journal-4355	136	36	so	so	ADV
american_scientific_journal-4355	136	37	considered	consider	VERB
american_scientific_journal-4355	136	38	as	as	ADP
american_scientific_journal-4355	136	39	a	a	DET
american_scientific_journal-4355	136	40	predictor	predictor	NOUN
american_scientific_journal-4355	136	41	of	of	ADP
american_scientific_journal-4355	136	42	fibrotic	fibrotic	ADJ
american_scientific_journal-4355	136	43	progression	progression	NOUN
american_scientific_journal-4355	136	44	[	[	X
american_scientific_journal-4355	136	45	31	31	NUM
american_scientific_journal-4355	136	46	]	]	PUNCT
american_scientific_journal-4355	136	47	.	.	PUNCT
american_scientific_journal-4355	137	1	this	this	DET
american_scientific_journal-4355	137	2	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	137	3	express	express	VERB
american_scientific_journal-4355	137	4	alpha	alpha	ADJ
american_scientific_journal-4355	137	5	smooth	smooth	ADJ
american_scientific_journal-4355	137	6	muscle	muscle	NOUN
american_scientific_journal-4355	137	7	actin	actin	NOUN
american_scientific_journal-4355	137	8	that	that	PRON
american_scientific_journal-4355	137	9	is	be	AUX
american_scientific_journal-4355	137	10	related	relate	VERB
american_scientific_journal-4355	137	11	to	to	ADP
american_scientific_journal-4355	137	12	intracellular	intracellular	ADJ
american_scientific_journal-4355	137	13	stress	stress	NOUN
american_scientific_journal-4355	137	14	fibres	fibre	NOUN
american_scientific_journal-4355	137	15	,	,	PUNCT
american_scientific_journal-4355	137	16	in	in	ADP
american_scientific_journal-4355	137	17	advanced	advanced	ADJ
american_scientific_journal-4355	137	18	disease	disease	NOUN
american_scientific_journal-4355	137	19	,	,	PUNCT
american_scientific_journal-4355	137	20	the	the	DET
american_scientific_journal-4355	137	21	interstitium	interstitium	NOUN
american_scientific_journal-4355	137	22	becomes	becomes	AUX
american_scientific_journal-4355	137	23	filled	fill	VERB
american_scientific_journal-4355	137	24	with	with	ADP
american_scientific_journal-4355	137	25	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	137	26	.	.	PUNCT
american_scientific_journal-4355	138	1	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	138	2	are	be	AUX
american_scientific_journal-4355	138	3	derived	derive	VERB
american_scientific_journal-4355	138	4	from	from	ADP
american_scientific_journal-4355	138	5	a	a	DET
american_scientific_journal-4355	138	6	variety	variety	NOUN
american_scientific_journal-4355	138	7	of	of	ADP
american_scientific_journal-4355	138	8	sources	source	NOUN
american_scientific_journal-4355	138	9	including	include	VERB
american_scientific_journal-4355	138	10	resident	resident	ADJ
american_scientific_journal-4355	138	11	mesenchymal	mesenchymal	NOUN
american_scientific_journal-4355	138	12	cells	cell	NOUN
american_scientific_journal-4355	138	13	,	,	PUNCT
american_scientific_journal-4355	138	14	epithelial	epithelial	ADJ
american_scientific_journal-4355	138	15	and	and	CCONJ
american_scientific_journal-4355	138	16	endothelial	endothelial	NOUN
american_scientific_journal-4355	138	17	cells	cell	NOUN
american_scientific_journal-4355	138	18	which	which	PRON
american_scientific_journal-4355	138	19	is	be	AUX
american_scientific_journal-4355	138	20	called	call	VERB
american_scientific_journal-4355	138	21	epithelial	epithelial	ADJ
american_scientific_journal-4355	138	22	/	/	SYM
american_scientific_journal-4355	138	23	endothelial	endothelial	NOUN
american_scientific_journal-4355	138	24	-	-	PUNCT
american_scientific_journal-4355	138	25	mesenchymal	mesenchymal	NOUN
american_scientific_journal-4355	138	26	(	(	PUNCT
american_scientific_journal-4355	138	27	emt	emt	PROPN
american_scientific_journal-4355	138	28	/	/	SYM
american_scientific_journal-4355	138	29	endmt	endmt	PROPN
american_scientific_journal-4355	138	30	)	)	PUNCT
american_scientific_journal-4355	138	31	transition	transition	NOUN
american_scientific_journal-4355	138	32	,	,	PUNCT
american_scientific_journal-4355	138	33	and	and	CCONJ
american_scientific_journal-4355	138	34	from	from	ADP
american_scientific_journal-4355	138	35	circulating	circulate	VERB
american_scientific_journal-4355	138	36	fibroblast	fibroblast	ADJ
american_scientific_journal-4355	138	37	-	-	PUNCT
american_scientific_journal-4355	138	38	like	like	ADJ
american_scientific_journal-4355	138	39	cells	cell	NOUN
american_scientific_journal-4355	138	40	called	call	VERB
american_scientific_journal-4355	138	41	fibrocytes	fibrocyte	NOUN
american_scientific_journal-4355	138	42	that	that	PRON
american_scientific_journal-4355	138	43	are	be	AUX
american_scientific_journal-4355	138	44	derived	derive	VERB
american_scientific_journal-4355	138	45	from	from	ADP
american_scientific_journal-4355	138	46	bone	bone	NOUN
american_scientific_journal-4355	138	47	-	-	PUNCT
american_scientific_journal-4355	138	48	marrow	marrow	NOUN
american_scientific_journal-4355	138	49	stem	stem	NOUN
american_scientific_journal-4355	138	50	cells	cell	NOUN
american_scientific_journal-4355	138	51	[	[	X
american_scientific_journal-4355	138	52	32	32	NUM
american_scientific_journal-4355	138	53	]	]	PUNCT
american_scientific_journal-4355	138	54	.	.	PUNCT
american_scientific_journal-4355	139	1	there	there	PRON
american_scientific_journal-4355	139	2	is	be	VERB
american_scientific_journal-4355	139	3	also	also	ADV
american_scientific_journal-4355	139	4	what	what	PRON
american_scientific_journal-4355	139	5	is	be	AUX
american_scientific_journal-4355	139	6	called	call	VERB
american_scientific_journal-4355	139	7	exosomes	exosome	NOUN
american_scientific_journal-4355	139	8	which	which	PRON
american_scientific_journal-4355	139	9	could	could	AUX
american_scientific_journal-4355	139	10	trigger	trigger	VERB
american_scientific_journal-4355	139	11	elevated	elevated	ADJ
american_scientific_journal-4355	139	12	α	α	PRON
american_scientific_journal-4355	139	13	-	-	ADJ
american_scientific_journal-4355	139	14	smooth	smooth	ADJ
american_scientific_journal-4355	139	15	muscle	muscle	NOUN
american_scientific_journal-4355	139	16	actin	actin	NOUN
american_scientific_journal-4355	139	17	expression	expression	NOUN
american_scientific_journal-4355	139	18	and	and	CCONJ
american_scientific_journal-4355	139	19	differentiate	differentiate	VERB
american_scientific_journal-4355	139	20	fibroblast	fibroblast	ADV
american_scientific_journal-4355	139	21	into	into	ADP
american_scientific_journal-4355	139	22	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	139	23	,	,	PUNCT
american_scientific_journal-4355	139	24	this	this	DET
american_scientific_journal-4355	139	25	exosomes	exosome	NOUN
american_scientific_journal-4355	139	26	are	be	AUX
american_scientific_journal-4355	139	27	vesicles	vesicle	NOUN
american_scientific_journal-4355	139	28	secreted	secrete	VERB
american_scientific_journal-4355	139	29	by	by	ADP
american_scientific_journal-4355	139	30	diverse	diverse	ADJ
american_scientific_journal-4355	139	31	cell	cell	NOUN
american_scientific_journal-4355	139	32	types	type	NOUN
american_scientific_journal-4355	139	33	that	that	PRON
american_scientific_journal-4355	139	34	play	play	VERB
american_scientific_journal-4355	139	35	complex	complex	ADJ
american_scientific_journal-4355	139	36	roles	role	NOUN
american_scientific_journal-4355	139	37	in	in	ADP
american_scientific_journal-4355	139	38	intercellular	intercellular	ADJ
american_scientific_journal-4355	139	39	communication	communication	NOUN
american_scientific_journal-4355	139	40	.	.	PUNCT
american_scientific_journal-4355	140	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	140	2	did	do	AUX
american_scientific_journal-4355	140	3	not	not	PART
american_scientific_journal-4355	140	4	alter	alter	VERB
american_scientific_journal-4355	140	5	tβri	tβri	NOUN
american_scientific_journal-4355	140	6	or	or	CCONJ
american_scientific_journal-4355	140	7	tβrii	tβrii	NOUN
american_scientific_journal-4355	140	8	but	but	CCONJ
american_scientific_journal-4355	140	9	instead	instead	ADV
american_scientific_journal-4355	140	10	inhibit	inhibit	VERB
american_scientific_journal-4355	140	11	smad	smad	PROPN
american_scientific_journal-4355	140	12	2/3	2/3	NUM
american_scientific_journal-4355	140	13	,	,	PUNCT
american_scientific_journal-4355	140	14	akt	akt	PROPN
american_scientific_journal-4355	140	15	and	and	CCONJ
american_scientific_journal-4355	140	16	erk	erk	PROPN
american_scientific_journal-4355	140	17	phosphorylation	phosphorylation	NOUN
american_scientific_journal-4355	140	18	and	and	CCONJ
american_scientific_journal-4355	140	19	we	we	PRON
american_scientific_journal-4355	140	20	can	can	AUX
american_scientific_journal-4355	140	21	say	say	VERB
american_scientific_journal-4355	140	22	that	that	SCONJ
american_scientific_journal-4355	140	23	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	140	24	is	be	AUX
american_scientific_journal-4355	140	25	important	important	ADJ
american_scientific_journal-4355	140	26	for	for	ADP
american_scientific_journal-4355	140	27	tgf	tgf	PROPN
american_scientific_journal-4355	140	28	-	-	PUNCT
american_scientific_journal-4355	140	29	β	β	PROPN
american_scientific_journal-4355	140	30	signalling	signalling	NOUN
american_scientific_journal-4355	140	31	and	and	CCONJ
american_scientific_journal-4355	140	32	differentiation	differentiation	NOUN
american_scientific_journal-4355	140	33	in	in	ADP
american_scientific_journal-4355	140	34	myofibroblast	myofibroblast	NOUN
american_scientific_journal-4355	140	35	,	,	PUNCT
american_scientific_journal-4355	140	36	through	through	ADP
american_scientific_journal-4355	140	37	smad	smad	PROPN
american_scientific_journal-4355	140	38	dependent	dependent	ADJ
american_scientific_journal-4355	140	39	and	and	CCONJ
american_scientific_journal-4355	140	40	independent	independent	ADJ
american_scientific_journal-4355	140	41	pathways	pathway	NOUN
american_scientific_journal-4355	140	42	.	.	PUNCT
american_scientific_journal-4355	141	1	while	while	SCONJ
american_scientific_journal-4355	141	2	the	the	DET
american_scientific_journal-4355	141	3	smad	smad	PROPN
american_scientific_journal-4355	141	4	pathway	pathway	NOUN
american_scientific_journal-4355	141	5	is	be	AUX
american_scientific_journal-4355	141	6	essential	essential	ADJ
american_scientific_journal-4355	141	7	for	for	ADP
american_scientific_journal-4355	141	8	tgf	tgf	PROPN
american_scientific_journal-4355	141	9	-	-	PUNCT
american_scientific_journal-4355	141	10	β	β	NOUN
american_scientific_journal-4355	141	11	singnaing	singnae	VERB
american_scientific_journal-4355	141	12	it	it	PRON
american_scientific_journal-4355	141	13	also	also	ADV
american_scientific_journal-4355	141	14	signal	signal	VERB
american_scientific_journal-4355	141	15	a	a	DET
american_scientific_journal-4355	141	16	variety	variety	NOUN
american_scientific_journal-4355	141	17	of	of	ADP
american_scientific_journal-4355	141	18	smad	smad	ADJ
american_scientific_journal-4355	141	19	-	-	ADJ
american_scientific_journal-4355	141	20	independent	independent	ADJ
american_scientific_journal-4355	141	21	pathways	pathway	NOUN
american_scientific_journal-4355	141	22	as	as	ADP
american_scientific_journal-4355	141	23	mitogen	mitogen	NOUN
american_scientific_journal-4355	141	24	–	–	PUNCT
american_scientific_journal-4355	141	25	activated	activate	VERB
american_scientific_journal-4355	141	26	protein	protein	NOUN
american_scientific_journal-4355	141	27	kinase	kinase	NOUN
american_scientific_journal-4355	141	28	(	(	PUNCT
american_scientific_journal-4355	141	29	mapks	mapks	NOUN
american_scientific_journal-4355	141	30	)	)	PUNCT
american_scientific_journal-4355	141	31	and	and	CCONJ
american_scientific_journal-4355	141	32	phosphatidylinositol	phosphatidylinositol	NOUN
american_scientific_journal-4355	141	33	3	3	NUM
american_scientific_journal-4355	141	34	-	-	PUNCT
american_scientific_journal-4355	141	35	kinase	kinase	NOUN
american_scientific_journal-4355	141	36	(	(	PUNCT
american_scientific_journal-4355	141	37	p13k)-akt	p13k)-akt	NOUN
american_scientific_journal-4355	141	38	.	.	PUNCT
american_scientific_journal-4355	142	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	142	2	is	be	AUX
american_scientific_journal-4355	142	3	a	a	DET
american_scientific_journal-4355	142	4	transmembrane	transmembrane	ADJ
american_scientific_journal-4355	142	5	proteoglycan	proteoglycan	NOUN
american_scientific_journal-4355	142	6	and	and	CCONJ
american_scientific_journal-4355	142	7	shows	show	VERB
american_scientific_journal-4355	142	8	a	a	DET
american_scientific_journal-4355	142	9	large	large	ADJ
american_scientific_journal-4355	142	10	extracellular	extracellular	ADJ
american_scientific_journal-4355	142	11	domain	domain	NOUN
american_scientific_journal-4355	142	12	which	which	PRON
american_scientific_journal-4355	142	13	having	have	VERB
american_scientific_journal-4355	142	14	heparin	heparin	ADJ
american_scientific_journal-4355	142	15	and	and	CCONJ
american_scientific_journal-4355	142	16	chondroitin	chondroitin	NOUN
american_scientific_journal-4355	142	17	sulphate	sulphate	NOUN
american_scientific_journal-4355	142	18	glycosaminoglycan	glycosaminoglycan	NOUN
american_scientific_journal-4355	142	19	chain	chain	NOUN
american_scientific_journal-4355	142	20	but	but	CCONJ
american_scientific_journal-4355	142	21	without	without	ADP
american_scientific_journal-4355	142	22	kinase	kinase	PROPN
american_scientific_journal-4355	142	23	domain	domain	PROPN
american_scientific_journal-4355	142	24	.	.	PUNCT
american_scientific_journal-4355	143	1	figure	figure	NOUN
american_scientific_journal-4355	143	2	4	4	NUM
american_scientific_journal-4355	143	3	:	:	PUNCT
american_scientific_journal-4355	143	4	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	143	5	has	have	VERB
american_scientific_journal-4355	143	6	a	a	DET
american_scientific_journal-4355	143	7	dual	dual	ADJ
american_scientific_journal-4355	143	8	modulation	modulation	NOUN
american_scientific_journal-4355	143	9	of	of	ADP
american_scientific_journal-4355	143	10	tgf	tgf	PROPN
american_scientific_journal-4355	143	11	-	-	PUNCT
american_scientific_journal-4355	143	12	β	β	NOUN
american_scientific_journal-4355	143	13	activities	activity	NOUN
american_scientific_journal-4355	143	14	betaglycan	betaglycan	X
american_scientific_journal-4355	143	15	has	have	VERB
american_scientific_journal-4355	143	16	an	an	DET
american_scientific_journal-4355	143	17	important	important	ADJ
american_scientific_journal-4355	143	18	function	function	NOUN
american_scientific_journal-4355	143	19	in	in	ADP
american_scientific_journal-4355	143	20	cancer	cancer	NOUN
american_scientific_journal-4355	143	21	and	and	CCONJ
american_scientific_journal-4355	143	22	lost	lose	VERB
american_scientific_journal-4355	143	23	in	in	ADP
american_scientific_journal-4355	143	24	most	most	ADJ
american_scientific_journal-4355	143	25	of	of	ADP
american_scientific_journal-4355	143	26	non	non	ADJ
american_scientific_journal-4355	143	27	-	-	ADJ
american_scientific_journal-4355	143	28	small	small	ADJ
american_scientific_journal-4355	143	29	cell	cell	NOUN
american_scientific_journal-4355	143	30	lung	lung	NOUN
american_scientific_journal-4355	143	31	cancer	cancer	NOUN
american_scientific_journal-4355	143	32	,	,	PUNCT
american_scientific_journal-4355	143	33	its	its	PRON
american_scientific_journal-4355	143	34	downregulation	downregulation	NOUN
american_scientific_journal-4355	143	35	enhances	enhance	VERB
american_scientific_journal-4355	143	36	epithelial	epithelial	ADJ
american_scientific_journal-4355	143	37	to	to	ADP
american_scientific_journal-4355	143	38	mesenchymal	mesenchymal	ADJ
american_scientific_journal-4355	143	39	transition	transition	NOUN
american_scientific_journal-4355	143	40	(	(	PUNCT
american_scientific_journal-4355	143	41	emt	emt	PROPN
american_scientific_journal-4355	143	42	)	)	PUNCT
american_scientific_journal-4355	143	43	,	,	PUNCT
american_scientific_journal-4355	143	44	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	143	45	is	be	AUX
american_scientific_journal-4355	143	46	downregulated	downregulate	VERB
american_scientific_journal-4355	143	47	during	during	ADP
american_scientific_journal-4355	143	48	tgf	tgf	PROPN
american_scientific_journal-4355	143	49	-	-	PUNCT
american_scientific_journal-4355	143	50	β	β	PROPN
american_scientific_journal-4355	143	51	differentiation	differentiation	NOUN
american_scientific_journal-4355	143	52	of	of	ADP
american_scientific_journal-4355	143	53	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	143	54	and	and	CCONJ
american_scientific_journal-4355	143	55	this	this	PRON
american_scientific_journal-4355	143	56	imply	imply	VERB
american_scientific_journal-4355	143	57	the	the	DET
american_scientific_journal-4355	143	58	antifibrotic	antifibrotic	ADJ
american_scientific_journal-4355	143	59	action	action	NOUN
american_scientific_journal-4355	143	60	of	of	ADP
american_scientific_journal-4355	143	61	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	143	62	.	.	PUNCT
american_scientific_journal-4355	144	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	144	2	undergoes	undergo	VERB
american_scientific_journal-4355	144	3	ligand	ligand	NOUN
american_scientific_journal-4355	144	4	-	-	PUNCT
american_scientific_journal-4355	144	5	independent	independent	ADJ
american_scientific_journal-4355	144	6	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	144	7	shedding	shedding	NOUN
american_scientific_journal-4355	144	8	and	and	CCONJ
american_scientific_journal-4355	144	9	a	a	DET
american_scientific_journal-4355	144	10	stable	stable	ADJ
american_scientific_journal-4355	144	11	soluble	soluble	ADJ
american_scientific_journal-4355	144	12	fragment	fragment	NOUN
american_scientific_journal-4355	144	13	is	be	AUX
american_scientific_journal-4355	144	14	produced	produce	VERB
american_scientific_journal-4355	144	15	which	which	PRON
american_scientific_journal-4355	144	16	sequesters	sequester	VERB
american_scientific_journal-4355	144	17	tgf	tgf	PROPN
american_scientific_journal-4355	144	18	-	-	PUNCT
american_scientific_journal-4355	144	19	β	β	NOUN
american_scientific_journal-4355	144	20	.	.	PUNCT
american_scientific_journal-4355	145	1	this	this	DET
american_scientific_journal-4355	145	2	fragment	fragment	NOUN
american_scientific_journal-4355	145	3	has	have	AUX
american_scientific_journal-4355	145	4	got	get	VERB
american_scientific_journal-4355	145	5	a	a	DET
american_scientific_journal-4355	145	6	therapeutic	therapeutic	ADJ
american_scientific_journal-4355	145	7	significant	significant	NOUN
american_scientific_journal-4355	145	8	in	in	ADP
american_scientific_journal-4355	145	9	some	some	DET
american_scientific_journal-4355	145	10	tumors	tumor	NOUN
american_scientific_journal-4355	145	11	and	and	CCONJ
american_scientific_journal-4355	145	12	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	145	13	as	as	ADP
american_scientific_journal-4355	145	14	an	an	DET
american_scientific_journal-4355	145	15	inhibitor	inhibitor	NOUN
american_scientific_journal-4355	145	16	of	of	ADP
american_scientific_journal-4355	145	17	tgf	tgf	PROPN
american_scientific_journal-4355	145	18	-	-	PUNCT
american_scientific_journal-4355	145	19	β	β	NOUN
american_scientific_journal-4355	145	20	signaling	signal	VERB
american_scientific_journal-4355	145	21	.	.	PUNCT
american_scientific_journal-4355	146	1	in	in	ADP
american_scientific_journal-4355	146	2	addition	addition	NOUN
american_scientific_journal-4355	146	3	to	to	ADP
american_scientific_journal-4355	146	4	the	the	DET
american_scientific_journal-4355	146	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	146	6	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	146	7	it	it	PRON
american_scientific_journal-4355	146	8	has	have	VERB
american_scientific_journal-4355	146	9	also	also	ADV
american_scientific_journal-4355	146	10	cytoplasmic	cytoplasmic	ADJ
american_scientific_journal-4355	146	11	domain	domain	NOUN
american_scientific_journal-4355	146	12	which	which	PRON
american_scientific_journal-4355	146	13	modulates	modulate	VERB
american_scientific_journal-4355	146	14	tgf	tgf	PROPN
american_scientific_journal-4355	146	15	-	-	PUNCT
american_scientific_journal-4355	146	16	β	β	X
american_scientific_journal-4355	146	17	dependent	dependent	ADJ
american_scientific_journal-4355	146	18	and	and	CCONJ
american_scientific_journal-4355	146	19	independent	independent	ADJ
american_scientific_journal-4355	146	20	activation	activation	NOUN
american_scientific_journal-4355	146	21	of	of	ADP
american_scientific_journal-4355	146	22	p38	p38	NOUN
american_scientific_journal-4355	146	23	/	/	SYM
american_scientific_journal-4355	146	24	mapk	mapk	NOUN
american_scientific_journal-4355	146	25	which	which	PRON
american_scientific_journal-4355	146	26	still	still	ADV
american_scientific_journal-4355	146	27	not	not	PART
american_scientific_journal-4355	146	28	well	well	ADV
american_scientific_journal-4355	146	29	known	know	VERB
american_scientific_journal-4355	146	30	,	,	PUNCT
american_scientific_journal-4355	146	31	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	146	32	also	also	ADV
american_scientific_journal-4355	146	33	forms	form	VERB
american_scientific_journal-4355	146	34	a	a	DET
american_scientific_journal-4355	146	35	complex	complex	NOUN
american_scientific_journal-4355	146	36	with	with	ADP
american_scientific_journal-4355	146	37	syndcan-2	syndcan-2	NUM
american_scientific_journal-4355	146	38	which	which	PRON
american_scientific_journal-4355	146	39	is	be	AUX
american_scientific_journal-4355	146	40	important	important	ADJ
american_scientific_journal-4355	146	41	in	in	ADP
american_scientific_journal-4355	146	42	regulating	regulate	VERB
american_scientific_journal-4355	146	43	tgf	tgf	PROPN
american_scientific_journal-4355	146	44	-	-	PUNCT
american_scientific_journal-4355	146	45	β	β	NOUN
american_scientific_journal-4355	146	46	signalling	signalling	NOUN
american_scientific_journal-4355	146	47	and	and	CCONJ
american_scientific_journal-4355	146	48	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	146	49	.	.	PUNCT
american_scientific_journal-4355	147	1	betaglcan	betaglcan	PROPN
american_scientific_journal-4355	147	2	species	specie	NOUN
american_scientific_journal-4355	147	3	have	have	VERB
american_scientific_journal-4355	147	4	opposing	oppose	VERB
american_scientific_journal-4355	147	5	effects	effect	NOUN
american_scientific_journal-4355	147	6	on	on	ADP
american_scientific_journal-4355	147	7	tgf	tgf	PROPN
american_scientific_journal-4355	147	8	-	-	PUNCT
american_scientific_journal-4355	147	9	β	β	NOUN
american_scientific_journal-4355	147	10	signalling	signal	VERB
american_scientific_journal-4355	147	11	whereby	whereby	SCONJ
american_scientific_journal-4355	147	12	betaglycan	betaglycan	AUX
american_scientific_journal-4355	147	13	serving	serve	VERB
american_scientific_journal-4355	147	14	as	as	ADP
american_scientific_journal-4355	147	15	(	(	PUNCT
american_scientific_journal-4355	147	16	molecular	molecular	ADJ
american_scientific_journal-4355	147	17	switch	switch	NOUN
american_scientific_journal-4355	147	18	)	)	PUNCT
american_scientific_journal-4355	147	19	.	.	PUNCT
american_scientific_journal-4355	148	1	when	when	SCONJ
american_scientific_journal-4355	148	2	isolated	isolated	ADJ
american_scientific_journal-4355	148	3	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	148	4	cytoplasmic	cytoplasmic	ADJ
american_scientific_journal-4355	148	5	domain	domain	NOUN
american_scientific_journal-4355	148	6	is	be	AUX
american_scientific_journal-4355	148	7	inhibited	inhibit	VERB
american_scientific_journal-4355	148	8	it	it	PRON
american_scientific_journal-4355	148	9	leads	lead	VERB
american_scientific_journal-4355	148	10	to	to	PART
american_scientific_journal-4355	148	11	decrease	decrease	VERB
american_scientific_journal-4355	148	12	tgf	tgf	PROPN
american_scientific_journal-4355	148	13	-	-	PUNCT
american_scientific_journal-4355	148	14	β	β	NOUN
american_scientific_journal-4355	148	15	signaling	signal	VERB
american_scientific_journal-4355	148	16	through	through	ADP
american_scientific_journal-4355	148	17	activation	activation	NOUN
american_scientific_journal-4355	148	18	of	of	ADP
american_scientific_journal-4355	148	19	the	the	DET
american_scientific_journal-4355	148	20	p38	p38	NOUN
american_scientific_journal-4355	148	21	/	/	SYM
american_scientific_journal-4355	148	22	mapk	mapk	NOUN
american_scientific_journal-4355	148	23	pathway	pathway	NOUN
american_scientific_journal-4355	148	24	,	,	PUNCT
american_scientific_journal-4355	148	25	so	so	ADV
american_scientific_journal-4355	148	26	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	148	27	has	have	AUX
american_scientific_journal-4355	148	28	got	get	VERB
american_scientific_journal-4355	148	29	an	an	DET
american_scientific_journal-4355	148	30	essential	essential	ADJ
american_scientific_journal-4355	148	31	role	role	NOUN
american_scientific_journal-4355	148	32	in	in	ADP
american_scientific_journal-4355	148	33	mediating	mediate	VERB
american_scientific_journal-4355	148	34	the	the	DET
american_scientific_journal-4355	148	35	specificity	specificity	NOUN
american_scientific_journal-4355	148	36	of	of	ADP
american_scientific_journal-4355	148	37	tgf	tgf	PROPN
american_scientific_journal-4355	148	38	-	-	PUNCT
american_scientific_journal-4355	148	39	β	β	PROPN
american_scientific_journal-4355	148	40	signaling	signal	VERB
american_scientific_journal-4355	148	41	pathways	pathway	NOUN
american_scientific_journal-4355	148	42	.	.	PUNCT
american_scientific_journal-4355	149	1	genetic	genetic	ADJ
american_scientific_journal-4355	149	2	analysis	analysis	NOUN
american_scientific_journal-4355	149	3	to	to	PART
american_scientific_journal-4355	149	4	clarify	clarify	VERB
american_scientific_journal-4355	149	5	the	the	DET
american_scientific_journal-4355	149	6	role	role	NOUN
american_scientific_journal-4355	149	7	of	of	ADP
american_scientific_journal-4355	149	8	epithelial	epithelial	ADJ
american_scientific_journal-4355	149	9	cells	cell	NOUN
american_scientific_journal-4355	149	10	and	and	CCONJ
american_scientific_journal-4355	149	11	interstitial	interstitial	ADJ
american_scientific_journal-4355	149	12	cells	cell	NOUN
american_scientific_journal-4355	149	13	in	in	ADP
american_scientific_journal-4355	149	14	the	the	DET
american_scientific_journal-4355	149	15	generation	generation	NOUN
american_scientific_journal-4355	149	16	of	of	ADP
american_scientific_journal-4355	149	17	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	149	18	during	during	ADP
american_scientific_journal-4355	149	19	kidney	kidney	NOUN
american_scientific_journal-4355	149	20	injury	injury	NOUN
american_scientific_journal-4355	149	21	and	and	CCONJ
american_scientific_journal-4355	149	22	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	149	23	.	.	PUNCT
american_scientific_journal-4355	150	1	it	it	PRON
american_scientific_journal-4355	150	2	has	have	AUX
american_scientific_journal-4355	150	3	been	be	AUX
american_scientific_journal-4355	150	4	shown	show	VERB
american_scientific_journal-4355	150	5	that	that	SCONJ
american_scientific_journal-4355	150	6	there	there	PRON
american_scientific_journal-4355	150	7	is	be	VERB
american_scientific_journal-4355	150	8	a	a	DET
american_scientific_journal-4355	150	9	definitive	definitive	ADJ
american_scientific_journal-4355	150	10	evidence	evidence	NOUN
american_scientific_journal-4355	150	11	that	that	PRON
american_scientific_journal-4355	150	12	kidney	kidney	NOUN
american_scientific_journal-4355	150	13	epithelial	epithelial	ADJ
american_scientific_journal-4355	150	14	cells	cell	NOUN
american_scientific_journal-4355	150	15	do	do	AUX
american_scientific_journal-4355	150	16	not	not	PART
american_scientific_journal-4355	150	17	become	become	VERB
american_scientific_journal-4355	150	18	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	150	19	in	in	ADP
american_scientific_journal-4355	150	20	vivo	vivo	NOUN
american_scientific_journal-4355	150	21	,	,	PUNCT
american_scientific_journal-4355	150	22	but	but	CCONJ
american_scientific_journal-4355	150	23	show	show	VERB
american_scientific_journal-4355	150	24	that	that	SCONJ
american_scientific_journal-4355	150	25	interstitial	interstitial	ADJ
american_scientific_journal-4355	150	26	pericytes	pericyte	NOUN
american_scientific_journal-4355	150	27	are	be	AUX
american_scientific_journal-4355	150	28	myofibroblast	myofibroblast	NOUN
american_scientific_journal-4355	150	29	progenitors	progenitor	NOUN
american_scientific_journal-4355	150	30	in	in	ADP
american_scientific_journal-4355	150	31	fibrotic	fibrotic	ADJ
american_scientific_journal-4355	150	32	kidney	kidney	NOUN
american_scientific_journal-4355	150	33	disease	disease	NOUN
american_scientific_journal-4355	150	34	[	[	X
american_scientific_journal-4355	150	35	33,34	33,34	NOUN
american_scientific_journal-4355	150	36	]	]	SYM
american_scientific_journal-4355	150	37	.	.	PUNCT
american_scientific_journal-4355	151	1	2.5	2.5	NUM
american_scientific_journal-4355	151	2	.	.	PUNCT
american_scientific_journal-4355	152	1	the	the	DET
american_scientific_journal-4355	152	2	aim	aim	NOUN
american_scientific_journal-4355	152	3	of	of	ADP
american_scientific_journal-4355	152	4	this	this	DET
american_scientific_journal-4355	152	5	work	work	NOUN
american_scientific_journal-4355	152	6	the	the	DET
american_scientific_journal-4355	152	7	purpose	purpose	NOUN
american_scientific_journal-4355	152	8	of	of	ADP
american_scientific_journal-4355	152	9	work	work	NOUN
american_scientific_journal-4355	152	10	is	be	AUX
american_scientific_journal-4355	152	11	to	to	PART
american_scientific_journal-4355	152	12	examine	examine	VERB
american_scientific_journal-4355	152	13	the	the	DET
american_scientific_journal-4355	152	14	potential	potential	ADJ
american_scientific_journal-4355	152	15	role	role	NOUN
american_scientific_journal-4355	152	16	of	of	ADP
american_scientific_journal-4355	152	17	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	152	18	in	in	ADP
american_scientific_journal-4355	152	19	hk2	hk2	PROPN
american_scientific_journal-4355	152	20	cells	cell	NOUN
american_scientific_journal-4355	152	21	as	as	ADP
american_scientific_journal-4355	152	22	a	a	DET
american_scientific_journal-4355	152	23	regulator	regulator	NOUN
american_scientific_journal-4355	152	24	of	of	ADP
american_scientific_journal-4355	152	25	tgf	tgf	PROPN
american_scientific_journal-4355	152	26	-	-	PUNCT
american_scientific_journal-4355	152	27	β	β	PROPN
american_scientific_journal-4355	152	28	signalling	signal	VERB
american_scientific_journal-4355	152	29	in	in	ADP
american_scientific_journal-4355	152	30	the	the	DET
american_scientific_journal-4355	152	31	kidney	kidney	NOUN
american_scientific_journal-4355	152	32	in	in	ADP
american_scientific_journal-4355	152	33	terms	term	NOUN
american_scientific_journal-4355	152	34	of	of	ADP
american_scientific_journal-4355	152	35	expression	expression	NOUN
american_scientific_journal-4355	152	36	,	,	PUNCT
american_scientific_journal-4355	152	37	inhibition	inhibition	NOUN
american_scientific_journal-4355	152	38	and	and	CCONJ
american_scientific_journal-4355	152	39	any	any	DET
american_scientific_journal-4355	152	40	phenotypical	phenotypical	ADJ
american_scientific_journal-4355	152	41	changes	change	NOUN
american_scientific_journal-4355	152	42	such	such	ADJ
american_scientific_journal-4355	152	43	as	as	ADP
american_scientific_journal-4355	152	44	epithelial	epithelial	ADJ
american_scientific_journal-4355	152	45	-	-	PUNCT
american_scientific_journal-4355	152	46	mesenchymal	mesenchymal	NOUN
american_scientific_journal-4355	152	47	transition	transition	NOUN
american_scientific_journal-4355	152	48	associated	associate	VERB
american_scientific_journal-4355	152	49	.	.	PUNCT
american_scientific_journal-4355	153	1	the	the	DET
american_scientific_journal-4355	153	2	specific	specific	ADJ
american_scientific_journal-4355	153	3	aims	aim	NOUN
american_scientific_journal-4355	153	4	are	be	AUX
american_scientific_journal-4355	153	5	to	to	PART
american_scientific_journal-4355	153	6	:	:	PUNCT
american_scientific_journal-4355	153	7	1	1	X
american_scientific_journal-4355	153	8	.	.	X
american_scientific_journal-4355	153	9	examine	examine	VERB
american_scientific_journal-4355	153	10	the	the	DET
american_scientific_journal-4355	153	11	expression	expression	NOUN
american_scientific_journal-4355	153	12	and	and	CCONJ
american_scientific_journal-4355	153	13	inhibition	inhibition	NOUN
american_scientific_journal-4355	153	14	of	of	ADP
american_scientific_journal-4355	153	15	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	153	16	.	.	PUNCT
american_scientific_journal-4355	154	1	2	2	X
american_scientific_journal-4355	154	2	.	.	X
american_scientific_journal-4355	154	3	examine	examine	VERB
american_scientific_journal-4355	154	4	the	the	DET
american_scientific_journal-4355	154	5	effect	effect	NOUN
american_scientific_journal-4355	154	6	of	of	ADP
american_scientific_journal-4355	154	7	specific	specific	ADJ
american_scientific_journal-4355	154	8	sirna	sirna	PROPN
american_scientific_journal-4355	154	9	and	and	CCONJ
american_scientific_journal-4355	154	10	heparin	heparin	ADJ
american_scientific_journal-4355	154	11	sulphate	sulphate	NOUN
american_scientific_journal-4355	154	12	inhibitors	inhibitor	NOUN
american_scientific_journal-4355	154	13	on	on	ADP
american_scientific_journal-4355	154	14	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	154	15	expression	expression	NOUN
american_scientific_journal-4355	154	16	with	with	ADP
american_scientific_journal-4355	154	17	relation	relation	NOUN
american_scientific_journal-4355	154	18	to	to	ADP
american_scientific_journal-4355	154	19	smad	smad	PROPN
american_scientific_journal-4355	154	20	phosphorylation	phosphorylation	NOUN
american_scientific_journal-4355	154	21	of	of	ADP
american_scientific_journal-4355	154	22	tgf	tgf	PROPN
american_scientific_journal-4355	154	23	-	-	PUNCT
american_scientific_journal-4355	154	24	β	β	NOUN
american_scientific_journal-4355	154	25	.	.	NOUN
american_scientific_journal-4355	155	1	3	3	X
american_scientific_journal-4355	155	2	.	.	X
american_scientific_journal-4355	155	3	examine	examine	VERB
american_scientific_journal-4355	155	4	the	the	DET
american_scientific_journal-4355	155	5	role	role	NOUN
american_scientific_journal-4355	155	6	of	of	ADP
american_scientific_journal-4355	155	7	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	155	8	expression	expression	NOUN
american_scientific_journal-4355	155	9	on	on	ADP
american_scientific_journal-4355	155	10	α	α	NOUN
american_scientific_journal-4355	155	11	-	-	PUNCT
american_scientific_journal-4355	155	12	sma	sma	NOUN
american_scientific_journal-4355	155	13	and	and	CCONJ
american_scientific_journal-4355	155	14	e	e	NOUN
american_scientific_journal-4355	155	15	-	-	NOUN
american_scientific_journal-4355	155	16	cadherin	cadherin	NOUN
american_scientific_journal-4355	155	17	(	(	PUNCT
american_scientific_journal-4355	155	18	emt	emt	PROPN
american_scientific_journal-4355	155	19	)	)	PUNCT
american_scientific_journal-4355	155	20	.	.	PUNCT
american_scientific_journal-4355	156	1	4	4	X
american_scientific_journal-4355	156	2	.	.	X
american_scientific_journal-4355	156	3	these	these	DET
american_scientific_journal-4355	156	4	roles	role	NOUN
american_scientific_journal-4355	156	5	of	of	ADP
american_scientific_journal-4355	156	6	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	156	7	actions	action	NOUN
american_scientific_journal-4355	156	8	will	will	AUX
american_scientific_journal-4355	156	9	have	have	VERB
american_scientific_journal-4355	156	10	a	a	DET
american_scientific_journal-4355	156	11	potential	potential	ADJ
american_scientific_journal-4355	156	12	impact	impact	NOUN
american_scientific_journal-4355	156	13	on	on	ADP
american_scientific_journal-4355	156	14	tgf	tgf	PROPN
american_scientific_journal-4355	156	15	-	-	PUNCT
american_scientific_journal-4355	156	16	β	β	NOUN
american_scientific_journal-4355	156	17	,	,	PUNCT
american_scientific_journal-4355	156	18	which	which	PRON
american_scientific_journal-4355	156	19	is	be	AUX
american_scientific_journal-4355	156	20	the	the	DET
american_scientific_journal-4355	156	21	key	key	ADJ
american_scientific_journal-4355	156	22	factor	factor	NOUN
american_scientific_journal-4355	156	23	in	in	ADP
american_scientific_journal-4355	156	24	renal	renal	ADJ
american_scientific_journal-4355	156	25	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	156	26	.	.	PUNCT
american_scientific_journal-4355	157	1	2.6	2.6	NUM
american_scientific_journal-4355	157	2	.	.	PUNCT
american_scientific_journal-4355	157	3	induction	induction	NOUN
american_scientific_journal-4355	157	4	of	of	ADP
american_scientific_journal-4355	157	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	157	6	by	by	ADP
american_scientific_journal-4355	157	7	proximal	proximal	ADJ
american_scientific_journal-4355	157	8	tubular	tubular	ADJ
american_scientific_journal-4355	157	9	cells	cell	NOUN
american_scientific_journal-4355	157	10	the	the	DET
american_scientific_journal-4355	157	11	progression	progression	NOUN
american_scientific_journal-4355	157	12	of	of	ADP
american_scientific_journal-4355	157	13	renal	renal	ADJ
american_scientific_journal-4355	157	14	disease	disease	NOUN
american_scientific_journal-4355	157	15	is	be	AUX
american_scientific_journal-4355	157	16	correlated	correlate	VERB
american_scientific_journal-4355	157	17	with	with	ADP
american_scientific_journal-4355	157	18	the	the	DET
american_scientific_journal-4355	157	19	degree	degree	NOUN
american_scientific_journal-4355	157	20	of	of	ADP
american_scientific_journal-4355	157	21	renal	renal	ADJ
american_scientific_journal-4355	157	22	interstitial	interstitial	ADJ
american_scientific_journal-4355	157	23	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	157	24	.	.	PUNCT
american_scientific_journal-4355	158	1	it	it	PRON
american_scientific_journal-4355	158	2	has	have	AUX
american_scientific_journal-4355	158	3	already	already	ADV
american_scientific_journal-4355	158	4	been	be	AUX
american_scientific_journal-4355	158	5	demonstrated	demonstrate	VERB
american_scientific_journal-4355	158	6	that	that	SCONJ
american_scientific_journal-4355	158	7	proximal	proximal	ADJ
american_scientific_journal-4355	158	8	tubular	tubular	ADJ
american_scientific_journal-4355	158	9	epithelial	epithelial	ADJ
american_scientific_journal-4355	158	10	cells	cell	NOUN
american_scientific_journal-4355	158	11	(	(	PUNCT
american_scientific_journal-4355	158	12	ptc	ptc	PROPN
american_scientific_journal-4355	158	13	)	)	PUNCT
american_scientific_journal-4355	158	14	have	have	VERB
american_scientific_journal-4355	158	15	the	the	DET
american_scientific_journal-4355	158	16	potential	potential	NOUN
american_scientific_journal-4355	158	17	to	to	PART
american_scientific_journal-4355	158	18	contribute	contribute	VERB
american_scientific_journal-4355	158	19	to	to	ADP
american_scientific_journal-4355	158	20	the	the	DET
american_scientific_journal-4355	158	21	pathogenesis	pathogenesis	NOUN
american_scientific_journal-4355	158	22	of	of	ADP
american_scientific_journal-4355	158	23	renal	renal	ADJ
american_scientific_journal-4355	158	24	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	158	25	directly	directly	ADV
american_scientific_journal-4355	158	26	by	by	ADP
american_scientific_journal-4355	158	27	alterations	alteration	NOUN
american_scientific_journal-4355	158	28	in	in	ADP
american_scientific_journal-4355	158	29	the	the	DET
american_scientific_journal-4355	158	30	production	production	NOUN
american_scientific_journal-4355	158	31	of	of	ADP
american_scientific_journal-4355	158	32	components	component	NOUN
american_scientific_journal-4355	158	33	of	of	ADP
american_scientific_journal-4355	158	34	the	the	DET
american_scientific_journal-4355	158	35	extracellular	extracellular	ADJ
american_scientific_journal-4355	158	36	matrix	matrix	NOUN
american_scientific_journal-4355	158	37	and	and	CCONJ
american_scientific_journal-4355	158	38	indirectly	indirectly	ADV
american_scientific_journal-4355	158	39	by	by	ADP
american_scientific_journal-4355	158	40	the	the	DET
american_scientific_journal-4355	158	41	production	production	NOUN
american_scientific_journal-4355	158	42	of	of	ADP
american_scientific_journal-4355	158	43	profibrotic	profibrotic	ADJ
american_scientific_journal-4355	158	44	cytokines	cytokine	NOUN
american_scientific_journal-4355	159	1	[	[	X
american_scientific_journal-4355	159	2	35;36	35;36	NUM
american_scientific_journal-4355	159	3	]	]	PUNCT
american_scientific_journal-4355	159	4	,	,	PUNCT
american_scientific_journal-4355	159	5	and	and	CCONJ
american_scientific_journal-4355	159	6	we	we	PRON
american_scientific_journal-4355	159	7	can	can	AUX
american_scientific_journal-4355	159	8	see	see	VERB
american_scientific_journal-4355	159	9	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	159	10	expression	expression	NOUN
american_scientific_journal-4355	159	11	by	by	ADP
american_scientific_journal-4355	159	12	cytokines	cytokine	NOUN
american_scientific_journal-4355	159	13	and	and	CCONJ
american_scientific_journal-4355	159	14	tgf	tgf	PROPN
american_scientific_journal-4355	159	15	-	-	PUNCT
american_scientific_journal-4355	159	16	β	β	PROPN
american_scientific_journal-4355	159	17	by	by	ADP
american_scientific_journal-4355	159	18	different	different	ADJ
american_scientific_journal-4355	159	19	methods	method	NOUN
american_scientific_journal-4355	159	20	,	,	PUNCT
american_scientific_journal-4355	159	21	(	(	PUNCT
american_scientific_journal-4355	159	22	figures	figure	NOUN
american_scientific_journal-4355	159	23	4,5	4,5	NUM
american_scientific_journal-4355	159	24	)	)	PUNCT
american_scientific_journal-4355	159	25	:	:	PUNCT
american_scientific_journal-4355	159	26	figure	figure	VERB
american_scientific_journal-4355	159	27	5	5	NUM
american_scientific_journal-4355	159	28	:	:	PUNCT
american_scientific_journal-4355	159	29	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	159	30	expression	expression	NOUN
american_scientific_journal-4355	159	31	by	by	ADP
american_scientific_journal-4355	159	32	conventional	conventional	ADJ
american_scientific_journal-4355	159	33	pcr	pcr	PROPN
american_scientific_journal-4355	159	34	2.7	2.7	NUM
american_scientific_journal-4355	159	35	.	.	PUNCT
american_scientific_journal-4355	160	1	conventional	conventional	ADJ
american_scientific_journal-4355	160	2	pcr	pcr	NOUN
american_scientific_journal-4355	160	3	showing	show	VERB
american_scientific_journal-4355	160	4	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	160	5	expression	expression	NOUN
american_scientific_journal-4355	160	6	as	as	ADP
american_scientific_journal-4355	160	7	bands	band	NOUN
american_scientific_journal-4355	160	8	on	on	ADP
american_scientific_journal-4355	160	9	agarose	agarose	NOUN
american_scientific_journal-4355	160	10	gel	gel	NOUN
american_scientific_journal-4355	160	11	following	follow	VERB
american_scientific_journal-4355	160	12	no	no	DET
american_scientific_journal-4355	160	13	stimulation	stimulation	NOUN
american_scientific_journal-4355	160	14	,	,	PUNCT
american_scientific_journal-4355	160	15	following	follow	VERB
american_scientific_journal-4355	160	16	il-1	il-1	ADP
american_scientific_journal-4355	160	17	and	and	CCONJ
american_scientific_journal-4355	160	18	following	follow	VERB
american_scientific_journal-4355	160	19	il-6	il-6	NUM
american_scientific_journal-4355	160	20	stimulation	stimulation	NOUN
american_scientific_journal-4355	160	21	compared	compare	VERB
american_scientific_journal-4355	160	22	with	with	ADP
american_scientific_journal-4355	160	23	actin	actin	NOUN
american_scientific_journal-4355	160	24	bands	band	NOUN
american_scientific_journal-4355	160	25	figure	figure	VERB
american_scientific_journal-4355	160	26	6	6	NUM
american_scientific_journal-4355	160	27	:	:	PUNCT
american_scientific_journal-4355	160	28	conventional	conventional	ADJ
american_scientific_journal-4355	160	29	pcr	pcr	ADJ
american_scientific_journal-4355	160	30	confirmation	confirmation	NOUN
american_scientific_journal-4355	160	31	by	by	ADP
american_scientific_journal-4355	160	32	quantitative	quantitative	ADJ
american_scientific_journal-4355	160	33	(	(	PUNCT
american_scientific_journal-4355	160	34	q	q	ADJ
american_scientific_journal-4355	160	35	-	-	ADJ
american_scientific_journal-4355	160	36	pcr	pcr	ADJ
american_scientific_journal-4355	160	37	)	)	PUNCT
american_scientific_journal-4355	160	38	,	,	PUNCT
american_scientific_journal-4355	160	39	concentration	concentration	NOUN
american_scientific_journal-4355	160	40	dependent	dependent	ADJ
american_scientific_journal-4355	160	41	induction	induction	NOUN
american_scientific_journal-4355	160	42	(	(	PUNCT
american_scientific_journal-4355	160	43	il-1	il-1	NUM
american_scientific_journal-4355	160	44	,	,	PUNCT
american_scientific_journal-4355	160	45	il-6	il-6	NUM
american_scientific_journal-4355	160	46	and	and	CCONJ
american_scientific_journal-4355	160	47	tgf	tgf	PROPN
american_scientific_journal-4355	160	48	-	-	PUNCT
american_scientific_journal-4355	160	49	β	β	NOUN
american_scientific_journal-4355	160	50	)	)	PUNCT
american_scientific_journal-4355	160	51	of	of	ADP
american_scientific_journal-4355	160	52	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	160	53	expression	expression	NOUN
american_scientific_journal-4355	160	54	to	to	PART
american_scientific_journal-4355	160	55	identify	identify	VERB
american_scientific_journal-4355	160	56	the	the	DET
american_scientific_journal-4355	160	57	most	most	ADV
american_scientific_journal-4355	160	58	effective	effective	ADJ
american_scientific_journal-4355	160	59	dose	dose	NOUN
american_scientific_journal-4355	160	60	of	of	ADP
american_scientific_journal-4355	160	61	il-1	il-1	PRON
american_scientific_journal-4355	160	62	,	,	PUNCT
american_scientific_journal-4355	160	63	il-6	il-6	NOUN
american_scientific_journal-4355	160	64	or	or	CCONJ
american_scientific_journal-4355	160	65	tgf	tgf	PROPN
american_scientific_journal-4355	160	66	-	-	PUNCT
american_scientific_journal-4355	160	67	β	β	PROPN
american_scientific_journal-4355	160	68	that	that	PRON
american_scientific_journal-4355	160	69	produced	produce	VERB
american_scientific_journal-4355	160	70	the	the	DET
american_scientific_journal-4355	160	71	greatest	great	ADJ
american_scientific_journal-4355	160	72	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	160	73	expression	expression	NOUN
american_scientific_journal-4355	160	74	,	,	PUNCT
american_scientific_journal-4355	160	75	different	different	ADJ
american_scientific_journal-4355	160	76	concentrations	concentration	NOUN
american_scientific_journal-4355	160	77	of	of	ADP
american_scientific_journal-4355	160	78	cytokines	cytokine	NOUN
american_scientific_journal-4355	160	79	were	be	AUX
american_scientific_journal-4355	160	80	used	use	VERB
american_scientific_journal-4355	160	81	to	to	PART
american_scientific_journal-4355	160	82	stimulate	stimulate	VERB
american_scientific_journal-4355	160	83	hk2	hk2	NOUN
american_scientific_journal-4355	160	84	cells	cell	NOUN
american_scientific_journal-4355	160	85	at	at	ADP
american_scientific_journal-4355	160	86	the	the	DET
american_scientific_journal-4355	160	87	optimal	optimal	ADJ
american_scientific_journal-4355	160	88	time	time	NOUN
american_scientific_journal-4355	160	89	which	which	PRON
american_scientific_journal-4355	160	90	was	be	AUX
american_scientific_journal-4355	160	91	chosen	choose	VERB
american_scientific_journal-4355	160	92	as	as	ADP
american_scientific_journal-4355	160	93	12	12	NUM
american_scientific_journal-4355	160	94	hours.the	hours.the	DET
american_scientific_journal-4355	160	95	results	result	NOUN
american_scientific_journal-4355	160	96	revealed	reveal	VERB
american_scientific_journal-4355	160	97	that	that	SCONJ
american_scientific_journal-4355	160	98	0.5	0.5	NUM
american_scientific_journal-4355	160	99	ng	ng	NOUN
american_scientific_journal-4355	160	100	/	/	SYM
american_scientific_journal-4355	160	101	ml	ml	PROPN
american_scientific_journal-4355	160	102	was	be	AUX
american_scientific_journal-4355	160	103	the	the	DET
american_scientific_journal-4355	160	104	most	most	ADV
american_scientific_journal-4355	160	105	effective	effective	ADJ
american_scientific_journal-4355	160	106	dose	dose	NOUN
american_scientific_journal-4355	160	107	for	for	ADP
american_scientific_journal-4355	160	108	both	both	DET
american_scientific_journal-4355	160	109	il-1	il-1	ADP
american_scientific_journal-4355	160	110	and	and	CCONJ
american_scientific_journal-4355	160	111	il-6	il-6	NOUN
american_scientific_journal-4355	160	112	to	to	PART
american_scientific_journal-4355	160	113	produce	produce	VERB
american_scientific_journal-4355	160	114	maximum	maximum	ADJ
american_scientific_journal-4355	160	115	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	160	116	expression	expression	NOUN
american_scientific_journal-4355	160	117	while	while	SCONJ
american_scientific_journal-4355	160	118	10	10	NUM
american_scientific_journal-4355	160	119	ng	ng	NOUN
american_scientific_journal-4355	160	120	/	/	SYM
american_scientific_journal-4355	160	121	ml	ml	PROPN
american_scientific_journal-4355	160	122	was	be	AUX
american_scientific_journal-4355	160	123	the	the	DET
american_scientific_journal-4355	160	124	most	most	ADV
american_scientific_journal-4355	160	125	effective	effective	ADJ
american_scientific_journal-4355	160	126	dose	dose	NOUN
american_scientific_journal-4355	160	127	for	for	ADP
american_scientific_journal-4355	160	128	tgf	tgf	PROPN
american_scientific_journal-4355	160	129	-	-	PUNCT
american_scientific_journal-4355	160	130	β	β	PROPN
american_scientific_journal-4355	160	131	(	(	PUNCT
american_scientific_journal-4355	160	132	figures	figure	NOUN
american_scientific_journal-4355	160	133	7,8,9	7,8,9	NUM
american_scientific_journal-4355	160	134	)	)	PUNCT
american_scientific_journal-4355	160	135	:	:	PUNCT
american_scientific_journal-4355	160	136	figure	figure	VERB
american_scientific_journal-4355	160	137	7	7	NUM
american_scientific_journal-4355	160	138	:	:	PUNCT
american_scientific_journal-4355	160	139	dose	dose	VERB
american_scientific_journal-4355	160	140	dependent	dependent	ADJ
american_scientific_journal-4355	160	141	of	of	ADP
american_scientific_journal-4355	160	142	il-1	il-1	PUNCT
american_scientific_journal-4355	160	143	dose	dose	NOUN
american_scientific_journal-4355	160	144	concentration	concentration	NOUN
american_scientific_journal-4355	160	145	of	of	ADP
american_scientific_journal-4355	160	146	il-6	il-6	NOUN
american_scientific_journal-4355	160	147	figure	figure	NOUN
american_scientific_journal-4355	160	148	8	8	NUM
american_scientific_journal-4355	160	149	:	:	PUNCT
american_scientific_journal-4355	160	150	the	the	DET
american_scientific_journal-4355	160	151	most	most	ADV
american_scientific_journal-4355	160	152	effective	effective	ADJ
american_scientific_journal-4355	160	153	dose	dose	NOUN
american_scientific_journal-4355	160	154	of	of	ADP
american_scientific_journal-4355	160	155	the	the	DET
american_scientific_journal-4355	160	156	cytokine	cytokine	NOUN
american_scientific_journal-4355	160	157	(	(	PUNCT
american_scientific_journal-4355	160	158	il6	il6	NOUN
american_scientific_journal-4355	160	159	)	)	PUNCT
american_scientific_journal-4355	160	160	induced	induce	VERB
american_scientific_journal-4355	160	161	bg	bg	PROPN
american_scientific_journal-4355	160	162	express	express	NOUN
american_scientific_journal-4355	160	163	.	.	PUNCT
american_scientific_journal-4355	161	1	at	at	ADP
american_scientific_journal-4355	161	2	12	12	NUM
american_scientific_journal-4355	161	3	hours	hour	NOUN
american_scientific_journal-4355	161	4	’	'	PUNCT
american_scientific_journal-4355	161	5	:	:	PUNCT
american_scientific_journal-4355	161	6	figure	figure	VERB
american_scientific_journal-4355	161	7	9	9	NUM
american_scientific_journal-4355	161	8	:	:	PUNCT
american_scientific_journal-4355	161	9	the	the	DET
american_scientific_journal-4355	161	10	most	most	ADV
american_scientific_journal-4355	161	11	effective	effective	ADJ
american_scientific_journal-4355	161	12	dose	dose	NOUN
american_scientific_journal-4355	161	13	of	of	ADP
american_scientific_journal-4355	161	14	the	the	DET
american_scientific_journal-4355	161	15	cytokine	cytokine	NOUN
american_scientific_journal-4355	161	16	(	(	PUNCT
american_scientific_journal-4355	161	17	tgf	tgf	PROPN
american_scientific_journal-4355	161	18	-	-	PUNCT
american_scientific_journal-4355	161	19	β	β	NOUN
american_scientific_journal-4355	161	20	)	)	PUNCT
american_scientific_journal-4355	161	21	induced	induce	VERB
american_scientific_journal-4355	161	22	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	161	23	expression	expression	NOUN
american_scientific_journal-4355	161	24	at	at	ADP
american_scientific_journal-4355	161	25	12	12	NUM
american_scientific_journal-4355	161	26	hours	hour	NOUN
american_scientific_journal-4355	161	27	’	'	PUNCT
american_scientific_journal-4355	161	28	time	time	NOUN
american_scientific_journal-4355	161	29	point	point	NOUN
american_scientific_journal-4355	161	30	figure	figure	NOUN
american_scientific_journal-4355	161	31	10	10	NUM
american_scientific_journal-4355	161	32	:	:	PUNCT
american_scientific_journal-4355	161	33	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	161	34	and	and	CCONJ
american_scientific_journal-4355	161	35	its	its	PRON
american_scientific_journal-4355	161	36	degradation	degradation	NOUN
american_scientific_journal-4355	161	37	products	product	NOUN
american_scientific_journal-4355	161	38	himarktm	himarktm	PROPN
american_scientific_journal-4355	161	39	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	161	40	and	and	CCONJ
american_scientific_journal-4355	161	41	its	its	PRON
american_scientific_journal-4355	161	42	degredation	degredation	NOUN
american_scientific_journal-4355	161	43	products	product	NOUN
american_scientific_journal-4355	161	44	.	.	PUNCT
american_scientific_journal-4355	162	1	2.8	2.8	NUM
american_scientific_journal-4355	162	2	.	.	PUNCT
american_scientific_journal-4355	162	3	inhibition	inhibition	NOUN
american_scientific_journal-4355	162	4	of	of	ADP
american_scientific_journal-4355	162	5	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	162	6	expression	expression	NOUN
american_scientific_journal-4355	162	7	and	and	CCONJ
american_scientific_journal-4355	162	8	glycosylation	glycosylation	NOUN
american_scientific_journal-4355	162	9	knock	knock	NOUN
american_scientific_journal-4355	162	10	-	-	PUNCT
american_scientific_journal-4355	162	11	down	down	NOUN
american_scientific_journal-4355	162	12	of	of	ADP
american_scientific_journal-4355	162	13	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	162	14	was	be	AUX
american_scientific_journal-4355	162	15	achieved	achieve	VERB
american_scientific_journal-4355	162	16	by	by	ADP
american_scientific_journal-4355	162	17	using	use	VERB
american_scientific_journal-4355	162	18	specific	specific	ADJ
american_scientific_journal-4355	162	19	short	short	ADJ
american_scientific_journal-4355	162	20	interfering	interfere	VERB
american_scientific_journal-4355	162	21	rna	rna	PROPN
american_scientific_journal-4355	162	22	(	(	PUNCT
american_scientific_journal-4355	162	23	sirna	sirna	PROPN
american_scientific_journal-4355	162	24	)	)	PUNCT
american_scientific_journal-4355	162	25	to	to	PART
american_scientific_journal-4355	162	26	investigate	investigate	VERB
american_scientific_journal-4355	162	27	the	the	DET
american_scientific_journal-4355	162	28	optimal	optimal	ADJ
american_scientific_journal-4355	162	29	time	time	NOUN
american_scientific_journal-4355	162	30	of	of	ADP
american_scientific_journal-4355	162	31	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	162	32	knock	knock	VERB
american_scientific_journal-4355	162	33	-	-	PUNCT
american_scientific_journal-4355	162	34	down	down	NOUN
american_scientific_journal-4355	162	35	,	,	PUNCT
american_scientific_journal-4355	162	36	what	what	PRON
american_scientific_journal-4355	162	37	happened	happen	VERB
american_scientific_journal-4355	162	38	to	to	ADP
american_scientific_journal-4355	162	39	tgf	tgf	PROPN
american_scientific_journal-4355	162	40	-	-	PUNCT
american_scientific_journal-4355	162	41	β1	β1	NOUN
american_scientific_journal-4355	162	42	signalling	signalling	NOUN
american_scientific_journal-4355	162	43	and	and	CCONJ
american_scientific_journal-4355	162	44	any	any	DET
american_scientific_journal-4355	162	45	phenotypical	phenotypical	ADJ
american_scientific_journal-4355	162	46	changes	change	NOUN
american_scientific_journal-4355	162	47	to	to	ADP
american_scientific_journal-4355	162	48	the	the	DET
american_scientific_journal-4355	162	49	immortalized	immortalized	ADJ
american_scientific_journal-4355	162	50	hk2	hk2	NOUN
american_scientific_journal-4355	162	51	cells	cell	NOUN
american_scientific_journal-4355	162	52	.	.	PUNCT
american_scientific_journal-4355	163	1	whether	whether	SCONJ
american_scientific_journal-4355	163	2	the	the	DET
american_scientific_journal-4355	163	3	glycosylation	glycosylation	NOUN
american_scientific_journal-4355	163	4	of	of	ADP
american_scientific_journal-4355	163	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	163	6	was	be	AUX
american_scientific_journal-4355	163	7	also	also	ADV
american_scientific_journal-4355	163	8	important	important	ADJ
american_scientific_journal-4355	163	9	for	for	SCONJ
american_scientific_journal-4355	163	10	its	its	PRON
american_scientific_journal-4355	163	11	function	function	NOUN
american_scientific_journal-4355	163	12	was	be	AUX
american_scientific_journal-4355	163	13	investigated	investigate	VERB
american_scientific_journal-4355	163	14	using	use	VERB
american_scientific_journal-4355	163	15	p	p	NOUN
american_scientific_journal-4355	163	16	-	-	PUNCT
american_scientific_journal-4355	163	17	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	163	18	-	-	PUNCT
american_scientific_journal-4355	163	19	β	β	NOUN
american_scientific_journal-4355	163	20	-	-	PUNCT
american_scientific_journal-4355	163	21	d	d	NOUN
american_scientific_journal-4355	163	22	-	-	NOUN
american_scientific_journal-4355	163	23	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	163	24	to	to	PART
american_scientific_journal-4355	163	25	inhibit	inhibit	VERB
american_scientific_journal-4355	163	26	glycosylation	glycosylation	NOUN
american_scientific_journal-4355	163	27	.	.	PUNCT
american_scientific_journal-4355	164	1	2.9	2.9	NUM
american_scientific_journal-4355	164	2	.	.	PUNCT
american_scientific_journal-4355	165	1	optimising	optimise	VERB
american_scientific_journal-4355	165	2	transfection	transfection	NOUN
american_scientific_journal-4355	165	3	time	time	NOUN
american_scientific_journal-4355	165	4	the	the	DET
american_scientific_journal-4355	165	5	incubation	incubation	NOUN
american_scientific_journal-4355	165	6	time	time	NOUN
american_scientific_journal-4355	165	7	required	require	VERB
american_scientific_journal-4355	165	8	for	for	ADP
american_scientific_journal-4355	165	9	maximal	maximal	ADJ
american_scientific_journal-4355	165	10	knockdown	knockdown	NOUN
american_scientific_journal-4355	165	11	of	of	ADP
american_scientific_journal-4355	165	12	the	the	DET
american_scientific_journal-4355	165	13	target	target	NOUN
american_scientific_journal-4355	165	14	gene	gene	NOUN
american_scientific_journal-4355	165	15	can	can	AUX
american_scientific_journal-4355	165	16	vary	vary	VERB
american_scientific_journal-4355	165	17	depending	depend	VERB
american_scientific_journal-4355	165	18	on	on	ADP
american_scientific_journal-4355	165	19	the	the	DET
american_scientific_journal-4355	165	20	specific	specific	ADJ
american_scientific_journal-4355	165	21	sirna	sirna	PROPN
american_scientific_journal-4355	165	22	used	use	VERB
american_scientific_journal-4355	165	23	,	,	PUNCT
american_scientific_journal-4355	165	24	and	and	CCONJ
american_scientific_journal-4355	165	25	therefore	therefore	ADV
american_scientific_journal-4355	165	26	the	the	DET
american_scientific_journal-4355	165	27	optimal	optimal	ADJ
american_scientific_journal-4355	165	28	transfection	transfection	NOUN
american_scientific_journal-4355	165	29	time	time	NOUN
american_scientific_journal-4355	165	30	for	for	ADP
american_scientific_journal-4355	165	31	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	165	32	was	be	AUX
american_scientific_journal-4355	165	33	determined	determine	VERB
american_scientific_journal-4355	165	34	prior	prior	ADV
american_scientific_journal-4355	165	35	to	to	ADP
american_scientific_journal-4355	165	36	further	further	ADJ
american_scientific_journal-4355	165	37	experimentation.betaglycan	experimentation.betaglycan	NOUN
american_scientific_journal-4355	165	38	was	be	AUX
american_scientific_journal-4355	165	39	knocked	knock	VERB
american_scientific_journal-4355	165	40	-	-	PUNCT
american_scientific_journal-4355	165	41	down	down	ADP
american_scientific_journal-4355	165	42	by	by	ADP
american_scientific_journal-4355	165	43	transfection	transfection	NOUN
american_scientific_journal-4355	165	44	with	with	ADP
american_scientific_journal-4355	165	45	specific	specific	ADJ
american_scientific_journal-4355	165	46	sirna	sirna	PROPN
american_scientific_journal-4355	165	47	.	.	PUNCT
american_scientific_journal-4355	166	1	in	in	ADP
american_scientific_journal-4355	166	2	the	the	DET
american_scientific_journal-4355	166	3	following	follow	VERB
american_scientific_journal-4355	166	4	experiment	experiment	NOUN
american_scientific_journal-4355	166	5	,	,	PUNCT
american_scientific_journal-4355	166	6	determination	determination	NOUN
american_scientific_journal-4355	166	7	of	of	ADP
american_scientific_journal-4355	166	8	the	the	DET
american_scientific_journal-4355	166	9	optimal	optimal	ADJ
american_scientific_journal-4355	166	10	time	time	NOUN
american_scientific_journal-4355	166	11	of	of	ADP
american_scientific_journal-4355	166	12	knock	knock	NOUN
american_scientific_journal-4355	166	13	-	-	PUNCT
american_scientific_journal-4355	166	14	down	down	NOUN
american_scientific_journal-4355	166	15	will	will	AUX
american_scientific_journal-4355	166	16	help	help	VERB
american_scientific_journal-4355	166	17	;	;	PUNCT
american_scientific_journal-4355	166	18	namely	namely	ADV
american_scientific_journal-4355	166	19	at	at	ADP
american_scientific_journal-4355	166	20	what	what	DET
american_scientific_journal-4355	166	21	time	time	NOUN
american_scientific_journal-4355	166	22	tgf	tgf	PROPN
american_scientific_journal-4355	166	23	-	-	PUNCT
american_scientific_journal-4355	166	24	β	β	PROPN
american_scientific_journal-4355	166	25	can	can	AUX
american_scientific_journal-4355	166	26	be	be	AUX
american_scientific_journal-4355	166	27	best	well	ADV
american_scientific_journal-4355	166	28	controlled	control	VERB
american_scientific_journal-4355	166	29	by	by	ADP
american_scientific_journal-4355	166	30	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	166	31	.	.	PUNCT
american_scientific_journal-4355	167	1	the	the	DET
american_scientific_journal-4355	167	2	concentration	concentration	NOUN
american_scientific_journal-4355	167	3	of	of	ADP
american_scientific_journal-4355	167	4	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	167	5	sirna	sirna	PROPN
american_scientific_journal-4355	167	6	was	be	AUX
american_scientific_journal-4355	167	7	20	20	NUM
american_scientific_journal-4355	167	8	mmolar	mmolar	ADJ
american_scientific_journal-4355	167	9	,	,	PUNCT
american_scientific_journal-4355	167	10	the	the	DET
american_scientific_journal-4355	167	11	scramble	scramble	ADJ
american_scientific_journal-4355	167	12	concentration	concentration	NOUN
american_scientific_journal-4355	167	13	was	be	AUX
american_scientific_journal-4355	167	14	40	40	NUM
american_scientific_journal-4355	167	15	pmol	pmol	X
american_scientific_journal-4355	167	16	per	per	ADP
american_scientific_journal-4355	167	17	microlitre	microlitre	NOUN
american_scientific_journal-4355	167	18	and	and	CCONJ
american_scientific_journal-4355	167	19	the	the	DET
american_scientific_journal-4355	167	20	end	end	NOUN
american_scientific_journal-4355	167	21	concentration	concentration	NOUN
american_scientific_journal-4355	167	22	was	be	AUX
american_scientific_journal-4355	167	23	33	33	NUM
american_scientific_journal-4355	167	24	nm	nm	NOUN
american_scientific_journal-4355	167	25	/	/	SYM
american_scientific_journal-4355	167	26	well	well	ADV
american_scientific_journal-4355	167	27	.	.	PUNCT
american_scientific_journal-4355	168	1	the	the	DET
american_scientific_journal-4355	168	2	degree	degree	NOUN
american_scientific_journal-4355	168	3	of	of	ADP
american_scientific_journal-4355	168	4	tgf	tgf	PROPN
american_scientific_journal-4355	168	5	-	-	PUNCT
american_scientific_journal-4355	168	6	βiii	βiii	NOUN
american_scientific_journal-4355	168	7	knock	knock	NOUN
american_scientific_journal-4355	168	8	-	-	PUNCT
american_scientific_journal-4355	168	9	down	down	NOUN
american_scientific_journal-4355	168	10	was	be	AUX
american_scientific_journal-4355	168	11	measured	measure	VERB
american_scientific_journal-4355	168	12	by	by	ADP
american_scientific_journal-4355	168	13	q	q	NOUN
american_scientific_journal-4355	168	14	-	-	PUNCT
american_scientific_journal-4355	168	15	pcr	pcr	ADJ
american_scientific_journal-4355	168	16	.	.	PUNCT
american_scientific_journal-4355	169	1	cells	cell	NOUN
american_scientific_journal-4355	169	2	were	be	AUX
american_scientific_journal-4355	169	3	transfected	transfecte	VERB
american_scientific_journal-4355	169	4	with	with	ADP
american_scientific_journal-4355	169	5	sirna	sirna	PROPN
american_scientific_journal-4355	169	6	and	and	CCONJ
american_scientific_journal-4355	169	7	mrna	mrna	PROPN
american_scientific_journal-4355	169	8	extracted	extract	VERB
american_scientific_journal-4355	169	9	for	for	ADP
american_scientific_journal-4355	169	10	times	time	NOUN
american_scientific_journal-4355	169	11	up	up	ADP
american_scientific_journal-4355	169	12	to	to	PART
american_scientific_journal-4355	169	13	72	72	NUM
american_scientific_journal-4355	169	14	hours	hour	NOUN
american_scientific_journal-4355	169	15	.	.	PUNCT
american_scientific_journal-4355	170	1	knock	knock	NOUN
american_scientific_journal-4355	170	2	-	-	PUNCT
american_scientific_journal-4355	170	3	down	down	NOUN
american_scientific_journal-4355	170	4	was	be	AUX
american_scientific_journal-4355	170	5	found	find	VERB
american_scientific_journal-4355	170	6	to	to	PART
american_scientific_journal-4355	170	7	be	be	AUX
american_scientific_journal-4355	170	8	maximal	maximal	ADJ
american_scientific_journal-4355	170	9	at	at	ADP
american_scientific_journal-4355	170	10	12	12	NUM
american_scientific_journal-4355	170	11	hours	hour	NOUN
american_scientific_journal-4355	170	12	onwards	onwards	ADV
american_scientific_journal-4355	170	13	(	(	PUNCT
american_scientific_journal-4355	170	14	figure	figure	NOUN
american_scientific_journal-4355	170	15	11	11	NUM
american_scientific_journal-4355	170	16	)	)	PUNCT
american_scientific_journal-4355	170	17	.	.	PUNCT
american_scientific_journal-4355	171	1	at	at	ADP
american_scientific_journal-4355	171	2	24	24	NUM
american_scientific_journal-4355	171	3	hours	hour	NOUN
american_scientific_journal-4355	171	4	80	80	NUM
american_scientific_journal-4355	171	5	%	%	NOUN
american_scientific_journal-4355	171	6	knock	knock	NOUN
american_scientific_journal-4355	171	7	-	-	PUNCT
american_scientific_journal-4355	171	8	down	down	NOUN
american_scientific_journal-4355	171	9	which	which	PRON
american_scientific_journal-4355	171	10	was	be	AUX
american_scientific_journal-4355	171	11	highly	highly	ADV
american_scientific_journal-4355	171	12	significant	significant	ADJ
american_scientific_journal-4355	171	13	(	(	PUNCT
american_scientific_journal-4355	171	14	figure	figure	NOUN
american_scientific_journal-4355	171	15	11	11	NUM
american_scientific_journal-4355	171	16	)	)	PUNCT
american_scientific_journal-4355	171	17	.	.	PUNCT
american_scientific_journal-4355	172	1	figure	figure	VERB
american_scientific_journal-4355	172	2	11	11	NUM
american_scientific_journal-4355	172	3	:	:	PUNCT
american_scientific_journal-4355	172	4	optimising	optimise	VERB
american_scientific_journal-4355	172	5	transfection	transfection	NOUN
american_scientific_journal-4355	172	6	time	time	NOUN
american_scientific_journal-4355	172	7	2.10	2.10	NUM
american_scientific_journal-4355	172	8	.	.	PUNCT
american_scientific_journal-4355	173	1	the	the	DET
american_scientific_journal-4355	173	2	bar	bar	NOUN
american_scientific_journal-4355	173	3	graphs	graph	NOUN
american_scientific_journal-4355	173	4	showing	show	VERB
american_scientific_journal-4355	173	5	the	the	DET
american_scientific_journal-4355	173	6	best	good	ADJ
american_scientific_journal-4355	173	7	time	time	NOUN
american_scientific_journal-4355	173	8	for	for	ADP
american_scientific_journal-4355	173	9	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	173	10	knock	knock	VERB
american_scientific_journal-4355	173	11	-	-	PUNCT
american_scientific_journal-4355	173	12	down	down	NOUN
american_scientific_journal-4355	173	13	,	,	PUNCT
american_scientific_journal-4355	173	14	every	every	DET
american_scientific_journal-4355	173	15	group	group	NOUN
american_scientific_journal-4355	173	16	done	do	VERB
american_scientific_journal-4355	173	17	individually	individually	ADV
american_scientific_journal-4355	173	18	and	and	CCONJ
american_scientific_journal-4355	173	19	compared	compare	VERB
american_scientific_journal-4355	173	20	to	to	ADP
american_scientific_journal-4355	173	21	its	its	PRON
american_scientific_journal-4355	173	22	own	own	ADJ
american_scientific_journal-4355	173	23	scramble	scramble	NOUN
american_scientific_journal-4355	173	24	the	the	DET
american_scientific_journal-4355	173	25	effect	effect	NOUN
american_scientific_journal-4355	173	26	of	of	ADP
american_scientific_journal-4355	173	27	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	173	28	sirna	sirna	PROPN
american_scientific_journal-4355	173	29	on	on	ADP
american_scientific_journal-4355	173	30	smad	smad	PROPN
american_scientific_journal-4355	173	31	-	-	PUNCT
american_scientific_journal-4355	173	32	iii	iii	NUM
american_scientific_journal-4355	173	33	phosphorlation	phosphorlation	NOUN
american_scientific_journal-4355	173	34	was	be	AUX
american_scientific_journal-4355	173	35	also	also	ADV
american_scientific_journal-4355	173	36	carried	carry	VERB
american_scientific_journal-4355	173	37	out	out	ADP
american_scientific_journal-4355	173	38	by	by	ADP
american_scientific_journal-4355	173	39	sds	sds	NOUN
american_scientific_journal-4355	173	40	-	-	PUNCT
american_scientific_journal-4355	173	41	page	page	NOUN
american_scientific_journal-4355	173	42	and	and	CCONJ
american_scientific_journal-4355	173	43	western	western	ADJ
american_scientific_journal-4355	173	44	blotting	blotting	NOUN
american_scientific_journal-4355	173	45	was	be	AUX
american_scientific_journal-4355	173	46	revealed	reveal	VERB
american_scientific_journal-4355	173	47	a	a	DET
american_scientific_journal-4355	173	48	significant	significant	ADJ
american_scientific_journal-4355	173	49	change	change	NOUN
american_scientific_journal-4355	173	50	of	of	ADP
american_scientific_journal-4355	173	51	p	p	NOUN
american_scientific_journal-4355	173	52	-	-	PUNCT
american_scientific_journal-4355	173	53	smad	smad	VERB
american_scientific_journal-4355	173	54	-	-	PUNCT
american_scientific_journal-4355	173	55	iii	iii	NUM
american_scientific_journal-4355	173	56	phosphorylation	phosphorylation	NOUN
american_scientific_journal-4355	173	57	(	(	PUNCT
american_scientific_journal-4355	173	58	figure	figure	NOUN
american_scientific_journal-4355	173	59	12	12	NUM
american_scientific_journal-4355	173	60	)	)	PUNCT
american_scientific_journal-4355	173	61	.	.	PUNCT
american_scientific_journal-4355	174	1	figure	figure	NOUN
american_scientific_journal-4355	174	2	12	12	NUM
american_scientific_journal-4355	174	3	:	:	PUNCT
american_scientific_journal-4355	174	4	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	174	5	core	core	NOUN
american_scientific_journal-4355	174	6	protein	protein	NOUN
american_scientific_journal-4355	174	7	inhibition	inhibition	NOUN
american_scientific_journal-4355	174	8	by	by	ADP
american_scientific_journal-4355	174	9	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	174	10	sirna	sirna	PROPN
american_scientific_journal-4355	174	11	transfection	transfection	NOUN
american_scientific_journal-4355	174	12	starting	start	VERB
american_scientific_journal-4355	174	13	with	with	ADP
american_scientific_journal-4355	174	14	the	the	DET
american_scientific_journal-4355	174	15	growing	growing	NOUN
american_scientific_journal-4355	174	16	of	of	ADP
american_scientific_journal-4355	174	17	hk2	hk2	NOUN
american_scientific_journal-4355	174	18	cells	cell	NOUN
american_scientific_journal-4355	174	19	until	until	SCONJ
american_scientific_journal-4355	174	20	they	they	PRON
american_scientific_journal-4355	174	21	become	become	VERB
american_scientific_journal-4355	174	22	50	50	NUM
american_scientific_journal-4355	174	23	%	%	NOUN
american_scientific_journal-4355	174	24	confluent	confluent	ADJ
american_scientific_journal-4355	174	25	,	,	PUNCT
american_scientific_journal-4355	174	26	they	they	PRON
american_scientific_journal-4355	174	27	were	be	AUX
american_scientific_journal-4355	174	28	kept	keep	VERB
american_scientific_journal-4355	174	29	in	in	ADP
american_scientific_journal-4355	174	30	serum	serum	NOUN
american_scientific_journal-4355	174	31	free	free	ADJ
american_scientific_journal-4355	174	32	media	medium	NOUN
american_scientific_journal-4355	174	33	overnight	overnight	ADV
american_scientific_journal-4355	174	34	then	then	ADV
american_scientific_journal-4355	174	35	transfected	transfecte	VERB
american_scientific_journal-4355	174	36	with	with	ADP
american_scientific_journal-4355	174	37	sirna	sirna	PROPN
american_scientific_journal-4355	174	38	and	and	CCONJ
american_scientific_journal-4355	174	39	incubated	incubate	VERB
american_scientific_journal-4355	174	40	for	for	ADP
american_scientific_journal-4355	174	41	72	72	NUM
american_scientific_journal-4355	174	42	hours	hour	NOUN
american_scientific_journal-4355	174	43	.	.	PUNCT
american_scientific_journal-4355	175	1	the	the	DET
american_scientific_journal-4355	175	2	cells	cell	NOUN
american_scientific_journal-4355	175	3	were	be	AUX
american_scientific_journal-4355	175	4	then	then	ADV
american_scientific_journal-4355	175	5	extracted	extract	VERB
american_scientific_journal-4355	175	6	for	for	ADP
american_scientific_journal-4355	175	7	protein	protein	NOUN
american_scientific_journal-4355	175	8	analysis	analysis	NOUN
american_scientific_journal-4355	175	9	by	by	ADP
american_scientific_journal-4355	175	10	sds	sds	NOUN
american_scientific_journal-4355	175	11	-	-	PUNCT
american_scientific_journal-4355	175	12	page	page	NOUN
american_scientific_journal-4355	175	13	and	and	CCONJ
american_scientific_journal-4355	175	14	western	western	ADJ
american_scientific_journal-4355	175	15	blotting	blotting	NOUN
american_scientific_journal-4355	175	16	carried	carry	VERB
american_scientific_journal-4355	175	17	out	out	ADP
american_scientific_journal-4355	175	18	.	.	PUNCT
american_scientific_journal-4355	176	1	there	there	PRON
american_scientific_journal-4355	176	2	was	be	VERB
american_scientific_journal-4355	176	3	a	a	DET
american_scientific_journal-4355	176	4	marked	mark	VERB
american_scientific_journal-4355	176	5	reduction	reduction	NOUN
american_scientific_journal-4355	176	6	in	in	ADP
american_scientific_journal-4355	176	7	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	176	8	protein	protein	NOUN
american_scientific_journal-4355	176	9	expression	expression	NOUN
american_scientific_journal-4355	176	10	in	in	ADP
american_scientific_journal-4355	176	11	knocked	knock	VERB
american_scientific_journal-4355	176	12	-	-	PUNCT
american_scientific_journal-4355	176	13	down	down	ADP
american_scientific_journal-4355	176	14	cells	cell	NOUN
american_scientific_journal-4355	176	15	(	(	PUNCT
american_scientific_journal-4355	176	16	figure	figure	NOUN
american_scientific_journal-4355	176	17	13	13	NUM
american_scientific_journal-4355	176	18	)	)	PUNCT
american_scientific_journal-4355	176	19	,	,	PUNCT
american_scientific_journal-4355	176	20	samples	sample	NOUN
american_scientific_journal-4355	176	21	were	be	AUX
american_scientific_journal-4355	176	22	compared	compare	VERB
american_scientific_journal-4355	176	23	to	to	ADP
american_scientific_journal-4355	176	24	gapdh	gapdh	NOUN
american_scientific_journal-4355	176	25	.	.	PUNCT
american_scientific_journal-4355	177	1	u	u	NOUN
american_scientific_journal-4355	177	2	=	=	NOUN
american_scientific_journal-4355	177	3	untransfected	untransfected	ADJ
american_scientific_journal-4355	177	4	samples	sample	NOUN
american_scientific_journal-4355	177	5	,	,	PUNCT
american_scientific_journal-4355	177	6	s	s	PART
american_scientific_journal-4355	177	7	=	=	VERB
american_scientific_journal-4355	177	8	scrambled	scramble	VERB
american_scientific_journal-4355	177	9	,	,	PUNCT
american_scientific_journal-4355	177	10	b(-	b(-	PROPN
american_scientific_journal-4355	177	11	)	)	PUNCT
american_scientific_journal-4355	177	12	=	=	PRON
american_scientific_journal-4355	177	13	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	177	14	knock	knock	VERB
american_scientific_journal-4355	177	15	-	-	PUNCT
american_scientific_journal-4355	177	16	down	down	NOUN
american_scientific_journal-4355	177	17	.	.	PUNCT
american_scientific_journal-4355	178	1	figure	figure	VERB
american_scientific_journal-4355	178	2	13	13	NUM
american_scientific_journal-4355	178	3	:	:	PUNCT
american_scientific_journal-4355	178	4	here	here	ADV
american_scientific_journal-4355	178	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	178	6	prevents	prevent	VERB
american_scientific_journal-4355	178	7	p	p	X
american_scientific_journal-4355	178	8	-	-	PUNCT
american_scientific_journal-4355	178	9	smad	smad	ADJ
american_scientific_journal-4355	178	10	iii	iii	NOUN
american_scientific_journal-4355	178	11	of	of	ADP
american_scientific_journal-4355	178	12	being	be	AUX
american_scientific_journal-4355	178	13	expressed	express	VERB
american_scientific_journal-4355	178	14	.	.	PUNCT
american_scientific_journal-4355	179	1	hk2	hk2	PROPN
american_scientific_journal-4355	179	2	cells	cell	NOUN
american_scientific_journal-4355	179	3	were	be	AUX
american_scientific_journal-4355	179	4	transfected	transfecte	VERB
american_scientific_journal-4355	179	5	and	and	CCONJ
american_scientific_journal-4355	179	6	30	30	NUM
american_scientific_journal-4355	179	7	western	western	ADJ
american_scientific_journal-4355	179	8	blotting	blotting	NOUN
american_scientific_journal-4355	179	9	carried	carry	VERB
american_scientific_journal-4355	179	10	out	out	ADP
american_scientific_journal-4355	179	11	.	.	PUNCT
american_scientific_journal-4355	180	1	gapdh	gapdh	NOUN
american_scientific_journal-4355	180	2	has	have	AUX
american_scientific_journal-4355	180	3	been	be	AUX
american_scientific_journal-4355	180	4	used	use	VERB
american_scientific_journal-4355	180	5	for	for	ADP
american_scientific_journal-4355	180	6	comparison	comparison	NOUN
american_scientific_journal-4355	180	7	.	.	PUNCT
american_scientific_journal-4355	181	1	st	st	PROPN
american_scientific_journal-4355	182	1	=	=	PRON
american_scientific_journal-4355	182	2	scramble	scramble	VERB
american_scientific_journal-4355	182	3	+	+	CCONJ
american_scientific_journal-4355	182	4	tgf	tgf	PROPN
american_scientific_journal-4355	182	5	-	-	PUNCT
american_scientific_journal-4355	182	6	β	β	NOUN
american_scientific_journal-4355	182	7	,	,	PUNCT
american_scientific_journal-4355	182	8	b(-)t	b(-)t	NOUN
american_scientific_journal-4355	182	9	=	=	SYM
american_scientific_journal-4355	182	10	betaglycan	betaglycan	AUX
american_scientific_journal-4355	182	11	knock	knock	VERB
american_scientific_journal-4355	182	12	-	-	PUNCT
american_scientific_journal-4355	182	13	down	down	ADP
american_scientific_journal-4355	182	14	+	+	CCONJ
american_scientific_journal-4355	182	15	tgf	tgf	PROPN
american_scientific_journal-4355	182	16	-	-	PUNCT
american_scientific_journal-4355	182	17	β	β	NOUN
american_scientific_journal-4355	182	18	.	.	PUNCT
american_scientific_journal-4355	183	1	the	the	DET
american_scientific_journal-4355	183	2	relationship	relationship	NOUN
american_scientific_journal-4355	183	3	of	of	ADP
american_scientific_journal-4355	183	4	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	183	5	knock	knock	VERB
american_scientific_journal-4355	183	6	-	-	PUNCT
american_scientific_journal-4355	183	7	down	down	NOUN
american_scientific_journal-4355	183	8	on	on	ADP
american_scientific_journal-4355	183	9	tgf	tgf	PROPN
american_scientific_journal-4355	183	10	-	-	PUNCT
american_scientific_journal-4355	183	11	β	β	NOUN
american_scientific_journal-4355	183	12	signalling	signal	VERB
american_scientific_journal-4355	183	13	in	in	ADP
american_scientific_journal-4355	183	14	terms	term	NOUN
american_scientific_journal-4355	183	15	o	o	X
american_scientific_journal-4355	183	16	p	p	X
american_scientific_journal-4355	183	17	-	-	PUNCT
american_scientific_journal-4355	183	18	smad	smad	VERB
american_scientific_journal-4355	183	19	-	-	PUNCT
american_scientific_journal-4355	183	20	iii	iii	NUM
american_scientific_journal-4355	183	21	phosphorylation	phosphorylation	NOUN
american_scientific_journal-4355	183	22	changes	change	NOUN
american_scientific_journal-4355	183	23	which	which	PRON
american_scientific_journal-4355	183	24	were	be	AUX
american_scientific_journal-4355	183	25	used	use	VERB
american_scientific_journal-4355	183	26	at	at	ADP
american_scientific_journal-4355	183	27	different	different	ADJ
american_scientific_journal-4355	183	28	time	time	NOUN
american_scientific_journal-4355	183	29	intervals	interval	NOUN
american_scientific_journal-4355	183	30	.	.	PUNCT
american_scientific_journal-4355	184	1	2.11	2.11	NUM
american_scientific_journal-4355	184	2	.	.	PUNCT
american_scientific_journal-4355	185	1	the	the	DET
american_scientific_journal-4355	185	2	relationship	relationship	NOUN
american_scientific_journal-4355	185	3	between	between	ADP
american_scientific_journal-4355	185	4	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	185	5	and	and	CCONJ
american_scientific_journal-4355	185	6	tgf	tgf	PROPN
american_scientific_journal-4355	185	7	-	-	PUNCT
american_scientific_journal-4355	185	8	β1	β1	PROPN
american_scientific_journal-4355	185	9	signalling	signal	VERB
american_scientific_journal-4355	185	10	following	follow	VERB
american_scientific_journal-4355	185	11	treatment	treatment	NOUN
american_scientific_journal-4355	185	12	with	with	ADP
american_scientific_journal-4355	185	13	p	p	NOUN
american_scientific_journal-4355	185	14	-	-	PUNCT
american_scientific_journal-4355	185	15	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	185	16	-	-	PUNCT
american_scientific_journal-4355	185	17	β	β	NOUN
american_scientific_journal-4355	185	18	-	-	PUNCT
american_scientific_journal-4355	185	19	d	d	NOUN
american_scientific_journal-4355	185	20	-	-	NOUN
american_scientific_journal-4355	185	21	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	185	22	(	(	PUNCT
american_scientific_journal-4355	185	23	dual	dual	ADJ
american_scientific_journal-4355	185	24	luciferase	luciferase	ADJ
american_scientific_journal-4355	185	25	enzyme	enzyme	NOUN
american_scientific_journal-4355	185	26	reporter	reporter	NOUN
american_scientific_journal-4355	185	27	)	)	PUNCT
american_scientific_journal-4355	185	28	the	the	DET
american_scientific_journal-4355	185	29	dual	dual	ADJ
american_scientific_journal-4355	185	30	luciferase	luciferase	NOUN
american_scientific_journal-4355	185	31	reporter	reporter	NOUN
american_scientific_journal-4355	185	32	assay	assay	PROPN
american_scientific_journal-4355	185	33	(	(	PUNCT
american_scientific_journal-4355	185	34	promega	promega	NOUN
american_scientific_journal-4355	185	35	)	)	PUNCT
american_scientific_journal-4355	185	36	has	have	AUX
american_scientific_journal-4355	185	37	been	be	AUX
american_scientific_journal-4355	185	38	used	use	VERB
american_scientific_journal-4355	185	39	to	to	PART
american_scientific_journal-4355	185	40	show	show	VERB
american_scientific_journal-4355	185	41	how	how	SCONJ
american_scientific_journal-4355	185	42	inhibition	inhibition	NOUN
american_scientific_journal-4355	185	43	of	of	ADP
american_scientific_journal-4355	185	44	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	185	45	heparan	heparan	ADJ
american_scientific_journal-4355	185	46	sulphate	sulphate	NOUN
american_scientific_journal-4355	185	47	with	with	ADP
american_scientific_journal-4355	185	48	p	p	NOUN
american_scientific_journal-4355	185	49	-	-	PUNCT
american_scientific_journal-4355	185	50	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	185	51	-	-	PUNCT
american_scientific_journal-4355	185	52	β	β	NOUN
american_scientific_journal-4355	185	53	-	-	ADJ
american_scientific_journal-4355	185	54	d	d	NOUN
american_scientific_journal-4355	185	55	-	-	PUNCT
american_scientific_journal-4355	185	56	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	185	57	regulates	regulate	VERB
american_scientific_journal-4355	185	58	and	and	CCONJ
american_scientific_journal-4355	185	59	affects	affect	VERB
american_scientific_journal-4355	185	60	tgf	tgf	PROPN
american_scientific_journal-4355	185	61	-	-	PUNCT
american_scientific_journal-4355	185	62	β	β	PROPN
american_scientific_journal-4355	185	63	signalling	signal	VERB
american_scientific_journal-4355	185	64	(	(	PUNCT
american_scientific_journal-4355	185	65	figure	figure	NOUN
american_scientific_journal-4355	185	66	14	14	NUM
american_scientific_journal-4355	185	67	)	)	PUNCT
american_scientific_journal-4355	185	68	.	.	PUNCT
american_scientific_journal-4355	186	1	removal	removal	NOUN
american_scientific_journal-4355	186	2	of	of	ADP
american_scientific_journal-4355	186	3	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	186	4	heparan	heparan	ADJ
american_scientific_journal-4355	186	5	sulphate	sulphate	NOUN
american_scientific_journal-4355	186	6	in	in	ADP
american_scientific_journal-4355	186	7	epithelial	epithelial	ADJ
american_scientific_journal-4355	186	8	cells	cell	NOUN
american_scientific_journal-4355	186	9	increases	increase	VERB
american_scientific_journal-4355	186	10	the	the	DET
american_scientific_journal-4355	186	11	ratio	ratio	NOUN
american_scientific_journal-4355	186	12	of	of	ADP
american_scientific_journal-4355	186	13	tgf	tgf	PROPN
american_scientific_journal-4355	186	14	-	-	PUNCT
american_scientific_journal-4355	186	15	β1	β1	PROPN
american_scientific_journal-4355	186	16	binding	bind	VERB
american_scientific_journal-4355	186	17	to	to	ADP
american_scientific_journal-4355	186	18	tβr	tβr	PROPN
american_scientific_journal-4355	186	19	-	-	PUNCT
american_scientific_journal-4355	186	20	ii	ii	PROPN
american_scientific_journal-4355	186	21	and	and	CCONJ
american_scientific_journal-4355	186	22	tβr	tβr	PROPN
american_scientific_journal-4355	186	23	-	-	PUNCT
american_scientific_journal-4355	186	24	i	i	PROPN
american_scientific_journal-4355	186	25	,	,	PUNCT
american_scientific_journal-4355	186	26	attenuates	attenuate	VERB
american_scientific_journal-4355	186	27	degradation	degradation	NOUN
american_scientific_journal-4355	186	28	of	of	ADP
american_scientific_journal-4355	186	29	tgf	tgf	PROPN
american_scientific_journal-4355	186	30	-	-	PUNCT
american_scientific_journal-4355	186	31	β1	β1	PROPN
american_scientific_journal-4355	186	32	.	.	PUNCT
american_scientific_journal-4355	187	1	augments	augment	VERB
american_scientific_journal-4355	187	2	tgf	tgf	PROPN
american_scientific_journal-4355	187	3	-	-	PUNCT
american_scientific_journal-4355	187	4	β1	β1	NOUN
american_scientific_journal-4355	187	5	-induced	-induce	VERB
american_scientific_journal-4355	187	6	cellular	cellular	ADJ
american_scientific_journal-4355	187	7	responses	response	NOUN
american_scientific_journal-4355	187	8	but	but	CCONJ
american_scientific_journal-4355	187	9	this	this	DET
american_scientific_journal-4355	187	10	action	action	NOUN
american_scientific_journal-4355	187	11	depends	depend	VERB
american_scientific_journal-4355	187	12	on	on	ADP
american_scientific_journal-4355	187	13	the	the	DET
american_scientific_journal-4355	187	14	magnitude	magnitude	NOUN
american_scientific_journal-4355	187	15	of	of	ADP
american_scientific_journal-4355	187	16	tgf	tgf	PROPN
american_scientific_journal-4355	187	17	-	-	PUNCT
american_scientific_journal-4355	187	18	β	β	PROPN
american_scientific_journal-4355	187	19	as	as	SCONJ
american_scientific_journal-4355	187	20	it	it	PRON
american_scientific_journal-4355	187	21	has	have	AUX
american_scientific_journal-4355	187	22	been	be	AUX
american_scientific_journal-4355	187	23	known	know	VERB
american_scientific_journal-4355	187	24	that	that	SCONJ
american_scientific_journal-4355	187	25	around	around	ADV
american_scientific_journal-4355	187	26	one	one	NUM
american_scientific_journal-4355	187	27	-	-	PUNCT
american_scientific_journal-4355	187	28	quarter	quarter	NOUN
american_scientific_journal-4355	187	29	of	of	ADP
american_scientific_journal-4355	187	30	tgf	tgf	PROPN
american_scientific_journal-4355	187	31	-	-	PUNCT
american_scientific_journal-4355	187	32	β	β	PROPN
american_scientific_journal-4355	187	33	has	have	AUX
american_scientific_journal-4355	187	34	been	be	AUX
american_scientific_journal-4355	187	35	shown	show	VERB
american_scientific_journal-4355	187	36	to	to	PART
american_scientific_journal-4355	187	37	bind	bind	VERB
american_scientific_journal-4355	187	38	to	to	ADP
american_scientific_journal-4355	187	39	heparan	heparan	ADJ
american_scientific_journal-4355	187	40	sulphate	sulphate	NOUN
american_scientific_journal-4355	188	1	[	[	X
american_scientific_journal-4355	188	2	43	43	NUM
american_scientific_journal-4355	188	3	]	]	PUNCT
american_scientific_journal-4355	188	4	.	.	PUNCT
american_scientific_journal-4355	189	1	figure	figure	NOUN
american_scientific_journal-4355	189	2	14	14	NUM
american_scientific_journal-4355	189	3	:	:	PUNCT
american_scientific_journal-4355	189	4	the	the	DET
american_scientific_journal-4355	189	5	relation	relation	NOUN
american_scientific_journal-4355	189	6	between	between	ADP
american_scientific_journal-4355	189	7	bg	bg	PROPN
american_scientific_journal-4355	189	8	and	and	CCONJ
american_scientific_journal-4355	189	9	tgf	tgf	PROPN
american_scientific_journal-4355	189	10	-	-	PUNCT
american_scientific_journal-4355	189	11	β	β	PROPN
american_scientific_journal-4355	189	12	following	follow	VERB
american_scientific_journal-4355	189	13	p	p	PROPN
american_scientific_journal-4355	189	14	-	-	PUNCT
american_scientific_journal-4355	189	15	n	n	CCONJ
american_scientific_journal-4355	189	16	-	-	PUNCT
american_scientific_journal-4355	189	17	xpyranoside	xpyranoside	NOUN
american_scientific_journal-4355	189	18	preparing	prepare	VERB
american_scientific_journal-4355	189	19	the	the	DET
american_scientific_journal-4355	189	20	white	white	ADJ
american_scientific_journal-4355	189	21	96	96	NUM
american_scientific_journal-4355	189	22	well	well	NOUN
american_scientific_journal-4355	189	23	plate	plate	NOUN
american_scientific_journal-4355	189	24	,	,	PUNCT
american_scientific_journal-4355	189	25	12	12	NUM
american_scientific_journal-4355	189	26	wells	well	NOUN
american_scientific_journal-4355	189	27	+	+	CCONJ
american_scientific_journal-4355	189	28	2	2	NUM
american_scientific_journal-4355	189	29	blank	blank	NOUN
american_scientific_journal-4355	189	30	+	+	NOUN
american_scientific_journal-4355	189	31	1	1	NUM
american_scientific_journal-4355	189	32	extra	extra	ADJ
american_scientific_journal-4355	189	33	=	=	SYM
american_scientific_journal-4355	189	34	15	15	NUM
american_scientific_journal-4355	189	35	wells	well	NOUN
american_scientific_journal-4355	189	36	,	,	PUNCT
american_scientific_journal-4355	189	37	dose	dose	NOUN
american_scientific_journal-4355	189	38	of	of	ADP
american_scientific_journal-4355	189	39	p	p	PROPN
american_scientific_journal-4355	189	40	-	-	PUNCT
american_scientific_journal-4355	189	41	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	189	42	-	-	PUNCT
american_scientific_journal-4355	189	43	β	β	NOUN
american_scientific_journal-4355	189	44	-	-	PUNCT
american_scientific_journal-4355	189	45	d	d	NOUN
american_scientific_journal-4355	189	46	-	-	PUNCT
american_scientific_journal-4355	189	47	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	189	48	is	be	AUX
american_scientific_journal-4355	189	49	0.406	0.406	NUM
american_scientific_journal-4355	189	50	milligram	milligram	NOUN
american_scientific_journal-4355	189	51	per	per	ADP
american_scientific_journal-4355	189	52	500	500	NUM
american_scientific_journal-4355	189	53	microlitre	microlitre	NOUN
american_scientific_journal-4355	189	54	in	in	ADP
american_scientific_journal-4355	189	55	each	each	DET
american_scientific_journal-4355	189	56	well	well	NOUN
american_scientific_journal-4355	189	57	,	,	PUNCT
american_scientific_journal-4355	189	58	and	and	CCONJ
american_scientific_journal-4355	189	59	for	for	ADP
american_scientific_journal-4355	189	60	tgf	tgf	PROPN
american_scientific_journal-4355	189	61	-	-	PUNCT
american_scientific_journal-4355	189	62	β	β	PROPN
american_scientific_journal-4355	189	63	is	be	AUX
american_scientific_journal-4355	189	64	1	1	NUM
american_scientific_journal-4355	189	65	microlitre	microlitre	NOUN
american_scientific_journal-4355	189	66	per	per	ADP
american_scientific_journal-4355	189	67	ml	ml	ADP
american_scientific_journal-4355	189	68	which	which	PRON
american_scientific_journal-4355	189	69	is	be	AUX
american_scientific_journal-4355	189	70	equal	equal	ADJ
american_scientific_journal-4355	189	71	to	to	ADP
american_scientific_journal-4355	189	72	1	1	NUM
american_scientific_journal-4355	189	73	ng	ng	PROPN
american_scientific_journal-4355	189	74	per	per	ADP
american_scientific_journal-4355	189	75	ml	ml	NOUN
american_scientific_journal-4355	189	76	.	.	PUNCT
american_scientific_journal-4355	190	1	cells	cell	NOUN
american_scientific_journal-4355	190	2	transfected	transfecte	VERB
american_scientific_journal-4355	190	3	with	with	ADP
american_scientific_journal-4355	190	4	the	the	DET
american_scientific_journal-4355	190	5	caga	caga	NOUN
american_scientific_journal-4355	190	6	-	-	PUNCT
american_scientific_journal-4355	190	7	luciferase	luciferase	NOUN
american_scientific_journal-4355	190	8	reporter	reporter	NOUN
american_scientific_journal-4355	190	9	construct	construct	NOUN
american_scientific_journal-4355	190	10	,	,	PUNCT
american_scientific_journal-4355	190	11	treated	treat	VERB
american_scientific_journal-4355	190	12	with	with	ADP
american_scientific_journal-4355	190	13	p	p	NOUN
american_scientific_journal-4355	190	14	-	-	PUNCT
american_scientific_journal-4355	190	15	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	190	16	-	-	PUNCT
american_scientific_journal-4355	190	17	β	β	NOUN
american_scientific_journal-4355	190	18	-	-	PUNCT
american_scientific_journal-4355	190	19	d	d	NOUN
american_scientific_journal-4355	190	20	-	-	PUNCT
american_scientific_journal-4355	190	21	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	190	22	(	(	PUNCT
american_scientific_journal-4355	190	23	single	single	ADJ
american_scientific_journal-4355	190	24	dose	dose	NOUN
american_scientific_journal-4355	190	25	)	)	PUNCT
american_scientific_journal-4355	190	26	,	,	PUNCT
american_scientific_journal-4355	190	27	tgf	tgf	PROPN
american_scientific_journal-4355	190	28	-	-	PUNCT
american_scientific_journal-4355	190	29	β	β	PROPN
american_scientific_journal-4355	190	30	stimulation	stimulation	NOUN
american_scientific_journal-4355	190	31	was	be	AUX
american_scientific_journal-4355	190	32	at	at	ADP
american_scientific_journal-4355	190	33	6	6	NUM
american_scientific_journal-4355	190	34	hours	hour	NOUN
american_scientific_journal-4355	190	35	.	.	PUNCT
american_scientific_journal-4355	191	1	four	four	NUM
american_scientific_journal-4355	191	2	groups	group	NOUN
american_scientific_journal-4355	191	3	used	use	VERB
american_scientific_journal-4355	191	4	in	in	ADP
american_scientific_journal-4355	191	5	the	the	DET
american_scientific_journal-4355	191	6	experiment	experiment	NOUN
american_scientific_journal-4355	191	7	(	(	PUNCT
american_scientific_journal-4355	191	8	control	control	PROPN
american_scientific_journal-4355	191	9	,	,	PUNCT
american_scientific_journal-4355	191	10	tgf	tgf	PROPN
american_scientific_journal-4355	191	11	-	-	PUNCT
american_scientific_journal-4355	191	12	β	β	PROPN
american_scientific_journal-4355	191	13	,	,	PUNCT
american_scientific_journal-4355	191	14	pxy	pxy	NOUN
american_scientific_journal-4355	191	15	,	,	PUNCT
american_scientific_journal-4355	191	16	both	both	PRON
american_scientific_journal-4355	191	17	)	)	PUNCT
american_scientific_journal-4355	191	18	.	.	PUNCT
american_scientific_journal-4355	192	1	the	the	DET
american_scientific_journal-4355	192	2	samples	sample	NOUN
american_scientific_journal-4355	192	3	were	be	AUX
american_scientific_journal-4355	192	4	incubated	incubate	VERB
american_scientific_journal-4355	192	5	for	for	ADP
american_scientific_journal-4355	192	6	72	72	NUM
american_scientific_journal-4355	192	7	hours	hour	NOUN
american_scientific_journal-4355	192	8	with	with	ADP
american_scientific_journal-4355	192	9	the	the	DET
american_scientific_journal-4355	192	10	inhibitor	inhibitor	NOUN
american_scientific_journal-4355	192	11	.	.	PUNCT
american_scientific_journal-4355	193	1	this	this	DET
american_scientific_journal-4355	193	2	experiment	experiment	NOUN
american_scientific_journal-4355	193	3	was	be	AUX
american_scientific_journal-4355	193	4	repeated	repeat	VERB
american_scientific_journal-4355	193	5	three	three	NUM
american_scientific_journal-4355	193	6	times	time	NOUN
american_scientific_journal-4355	193	7	.	.	PUNCT
american_scientific_journal-4355	194	1	┬	┬	PROPN
american_scientific_journal-4355	194	2	=	=	SYM
american_scientific_journal-4355	194	3	standard	standard	ADJ
american_scientific_journal-4355	194	4	deviation	deviation	NOUN
american_scientific_journal-4355	194	5	.	.	PUNCT
american_scientific_journal-4355	195	1	*	*	PUNCT
american_scientific_journal-4355	196	1	=	=	PUNCT
american_scientific_journal-4355	196	2	p	p	NUM
american_scientific_journal-4355	196	3	-	-	PUNCT
american_scientific_journal-4355	196	4	value	value	NOUN
american_scientific_journal-4355	196	5	=	=	PUNCT
american_scientific_journal-4355	196	6	˂	˂	NOUN
american_scientific_journal-4355	196	7	0.05	0.05	NUM
american_scientific_journal-4355	196	8	=	=	SYM
american_scientific_journal-4355	196	9	statistically	statistically	ADV
american_scientific_journal-4355	196	10	significant	significant	ADJ
american_scientific_journal-4355	196	11	=	=	PUNCT
american_scientific_journal-4355	196	12	˂	˂	NOUN
american_scientific_journal-4355	196	13	0.05	0.05	NUM
american_scientific_journal-4355	196	14	,	,	PUNCT
american_scientific_journal-4355	196	15	*	*	PUNCT
american_scientific_journal-4355	196	16	*	*	PUNCT
american_scientific_journal-4355	197	1	=	=	PUNCT
american_scientific_journal-4355	197	2	p	p	NUM
american_scientific_journal-4355	197	3	-	-	PUNCT
american_scientific_journal-4355	197	4	value	value	NOUN
american_scientific_journal-4355	197	5	=	=	PUNCT
american_scientific_journal-4355	197	6	highly	highly	ADV
american_scientific_journal-4355	197	7	significant	significant	ADJ
american_scientific_journal-4355	197	8	=	=	PUNCT
american_scientific_journal-4355	197	9	˂	˂	PROPN
american_scientific_journal-4355	197	10	0.03	0.03	NUM
american_scientific_journal-4355	197	11	,	,	PUNCT
american_scientific_journal-4355	197	12	control	control	NOUN
american_scientific_journal-4355	197	13	=	=	PUNCT
american_scientific_journal-4355	197	14	neither	neither	CCONJ
american_scientific_journal-4355	197	15	xy	xy	PROPN
american_scientific_journal-4355	197	16	nor	nor	CCONJ
american_scientific_journal-4355	197	17	tgf	tgf	PROPN
american_scientific_journal-4355	197	18	-	-	PUNCT
american_scientific_journal-4355	197	19	β	β	PROPN
american_scientific_journal-4355	197	20	was	be	AUX
american_scientific_journal-4355	197	21	applied	apply	VERB
american_scientific_journal-4355	197	22	.	.	PUNCT
american_scientific_journal-4355	198	1	xy	xy	X
american_scientific_journal-4355	199	1	=	=	PUNCT
american_scientific_journal-4355	199	2	p	p	X
american_scientific_journal-4355	199	3	-	-	PUNCT
american_scientific_journal-4355	199	4	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	199	5	-	-	PUNCT
american_scientific_journal-4355	199	6	β	β	NOUN
american_scientific_journal-4355	199	7	-	-	ADJ
american_scientific_journal-4355	199	8	d	d	NOUN
american_scientific_journal-4355	199	9	-	-	PUNCT
american_scientific_journal-4355	199	10	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	199	11	.	.	PUNCT
american_scientific_journal-4355	200	1	as	as	SCONJ
american_scientific_journal-4355	200	2	has	have	AUX
american_scientific_journal-4355	200	3	been	be	AUX
american_scientific_journal-4355	200	4	seen	see	VERB
american_scientific_journal-4355	200	5	from	from	ADP
american_scientific_journal-4355	200	6	the	the	DET
american_scientific_journal-4355	200	7	previous	previous	ADJ
american_scientific_journal-4355	200	8	experiment	experiment	NOUN
american_scientific_journal-4355	200	9	(	(	PUNCT
american_scientific_journal-4355	200	10	figure	figure	NOUN
american_scientific_journal-4355	200	11	14	14	NUM
american_scientific_journal-4355	200	12	)	)	PUNCT
american_scientific_journal-4355	200	13	,	,	PUNCT
american_scientific_journal-4355	200	14	the	the	DET
american_scientific_journal-4355	200	15	inhibition	inhibition	NOUN
american_scientific_journal-4355	200	16	of	of	ADP
american_scientific_journal-4355	200	17	the	the	DET
american_scientific_journal-4355	200	18	active	active	ADJ
american_scientific_journal-4355	200	19	part	part	NOUN
american_scientific_journal-4355	200	20	of	of	ADP
american_scientific_journal-4355	200	21	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	200	22	(	(	PUNCT
american_scientific_journal-4355	200	23	heparan	heparan	ADJ
american_scientific_journal-4355	200	24	sulphate	sulphate	NOUN
american_scientific_journal-4355	200	25	)	)	PUNCT
american_scientific_journal-4355	200	26	has	have	AUX
american_scientific_journal-4355	200	27	brought	bring	VERB
american_scientific_journal-4355	200	28	down	down	ADP
american_scientific_journal-4355	200	29	tgf	tgf	PROPN
american_scientific_journal-4355	200	30	-	-	PUNCT
american_scientific_journal-4355	200	31	β	β	PROPN
american_scientific_journal-4355	200	32	luminescence	luminescence	NOUN
american_scientific_journal-4355	200	33	level	level	NOUN
american_scientific_journal-4355	200	34	.	.	PUNCT
american_scientific_journal-4355	201	1	these	these	DET
american_scientific_journal-4355	201	2	results	result	NOUN
american_scientific_journal-4355	201	3	suggest	suggest	VERB
american_scientific_journal-4355	201	4	that	that	SCONJ
american_scientific_journal-4355	201	5	heparan	heparan	ADJ
american_scientific_journal-4355	201	6	sulfate	sulfate	NOUN
american_scientific_journal-4355	201	7	modulates	modulate	VERB
american_scientific_journal-4355	201	8	tgf	tgf	PROPN
american_scientific_journal-4355	201	9	-	-	PUNCT
american_scientific_journal-4355	201	10	β1	β1	PROPN
american_scientific_journal-4355	201	11	responsiveness	responsiveness	NOUN
american_scientific_journal-4355	201	12	by	by	ADP
american_scientific_journal-4355	201	13	decreasing	decrease	VERB
american_scientific_journal-4355	201	14	the	the	DET
american_scientific_journal-4355	201	15	ratio	ratio	NOUN
american_scientific_journal-4355	201	16	of	of	ADP
american_scientific_journal-4355	201	17	tgf	tgf	PROPN
american_scientific_journal-4355	201	18	-	-	PUNCT
american_scientific_journal-4355	201	19	β1	β1	PROPN
american_scientific_journal-4355	201	20	,	,	PUNCT
american_scientific_journal-4355	201	21	thus	thus	ADV
american_scientific_journal-4355	201	22	diminishing	diminish	VERB
american_scientific_journal-4355	201	23	signalling	signal	VERB
american_scientific_journal-4355	201	24	of	of	ADP
american_scientific_journal-4355	201	25	tgf	tgf	PROPN
american_scientific_journal-4355	201	26	-	-	PUNCT
american_scientific_journal-4355	201	27	β1	β1	PROPN
american_scientific_journal-4355	201	28	in	in	ADP
american_scientific_journal-4355	201	29	the	the	DET
american_scientific_journal-4355	201	30	epithelial	epithelial	ADJ
american_scientific_journal-4355	201	31	cells[44	cells[44	NOUN
american_scientific_journal-4355	201	32	]	]	PUNCT
american_scientific_journal-4355	201	33	.	.	PUNCT
american_scientific_journal-4355	202	1	generally	generally	ADV
american_scientific_journal-4355	202	2	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	202	3	has	have	VERB
american_scientific_journal-4355	202	4	an	an	DET
american_scientific_journal-4355	202	5	important	important	ADJ
american_scientific_journal-4355	202	6	impact	impact	NOUN
american_scientific_journal-4355	202	7	on	on	ADP
american_scientific_journal-4355	202	8	tgf	tgf	PROPN
american_scientific_journal-4355	202	9	-	-	PUNCT
american_scientific_journal-4355	202	10	β	β	NOUN
american_scientific_journal-4355	202	11	signalling	signal	VERB
american_scientific_journal-4355	202	12	as	as	SCONJ
american_scientific_journal-4355	202	13	it	it	PRON
american_scientific_journal-4355	202	14	affects	affect	VERB
american_scientific_journal-4355	202	15	the	the	DET
american_scientific_journal-4355	202	16	core	core	ADJ
american_scientific_journal-4355	202	17	protein	protein	NOUN
american_scientific_journal-4355	202	18	expression	expression	NOUN
american_scientific_journal-4355	202	19	and	and	CCONJ
american_scientific_journal-4355	202	20	subsequently	subsequently	ADV
american_scientific_journal-4355	202	21	the	the	DET
american_scientific_journal-4355	202	22	cell	cell	NOUN
american_scientific_journal-4355	202	23	functions	function	NOUN
american_scientific_journal-4355	202	24	,	,	PUNCT
american_scientific_journal-4355	202	25	when	when	SCONJ
american_scientific_journal-4355	202	26	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	202	27	blocked	block	VERB
american_scientific_journal-4355	202	28	,	,	PUNCT
american_scientific_journal-4355	202	29	its	its	PRON
american_scientific_journal-4355	202	30	bands	band	NOUN
american_scientific_journal-4355	202	31	down	down	ADV
american_scientific_journal-4355	202	32	-	-	PUNCT
american_scientific_journal-4355	202	33	regulated	regulate	VERB
american_scientific_journal-4355	202	34	and	and	CCONJ
american_scientific_journal-4355	202	35	phosphorylation	phosphorylation	NOUN
american_scientific_journal-4355	202	36	of	of	ADP
american_scientific_journal-4355	202	37	p	p	NOUN
american_scientific_journal-4355	202	38	-	-	PUNCT
american_scientific_journal-4355	202	39	smad	smad	PROPN
american_scientific_journal-4355	202	40	iii	iii	NOUN
american_scientific_journal-4355	202	41	has	have	AUX
american_scientific_journal-4355	202	42	changed	change	VERB
american_scientific_journal-4355	202	43	,	,	PUNCT
american_scientific_journal-4355	202	44	which	which	PRON
american_scientific_journal-4355	202	45	shows	show	VERB
american_scientific_journal-4355	202	46	how	how	SCONJ
american_scientific_journal-4355	202	47	significant	significant	ADJ
american_scientific_journal-4355	202	48	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	202	49	(	(	PUNCT
american_scientific_journal-4355	202	50	tgf	tgf	PROPN
american_scientific_journal-4355	202	51	-	-	PUNCT
american_scientific_journal-4355	202	52	β	β	NOUN
american_scientific_journal-4355	202	53	-	-	PUNCT
american_scientific_journal-4355	202	54	r	r	NOUN
american_scientific_journal-4355	202	55	iii	iii	NOUN
american_scientific_journal-4355	202	56	)	)	PUNCT
american_scientific_journal-4355	202	57	could	could	AUX
american_scientific_journal-4355	202	58	manage	manage	VERB
american_scientific_journal-4355	202	59	tgf	tgf	PROPN
american_scientific_journal-4355	202	60	-	-	PUNCT
american_scientific_journal-4355	202	61	β	β	NOUN
american_scientific_journal-4355	202	62	signalling	signal	VERB
american_scientific_journal-4355	202	63	in	in	ADP
american_scientific_journal-4355	202	64	the	the	DET
american_scientific_journal-4355	202	65	kidney	kidney	NOUN
american_scientific_journal-4355	202	66	.	.	PUNCT
american_scientific_journal-4355	203	1	2.12	2.12	NUM
american_scientific_journal-4355	203	2	.	.	PUNCT
american_scientific_journal-4355	204	1	the	the	DET
american_scientific_journal-4355	204	2	effect	effect	NOUN
american_scientific_journal-4355	204	3	of	of	ADP
american_scientific_journal-4355	204	4	p	p	NOUN
american_scientific_journal-4355	204	5	-	-	PUNCT
american_scientific_journal-4355	204	6	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	204	7	-	-	PUNCT
american_scientific_journal-4355	204	8	β	β	NOUN
american_scientific_journal-4355	204	9	-	-	ADJ
american_scientific_journal-4355	204	10	d	d	NOUN
american_scientific_journal-4355	204	11	-	-	PUNCT
american_scientific_journal-4355	204	12	xylopyranoside	xylopyranoside	ADJ
american_scientific_journal-4355	204	13	treatment	treatment	NOUN
american_scientific_journal-4355	204	14	on	on	ADP
american_scientific_journal-4355	204	15	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	204	16	protein	protein	NOUN
american_scientific_journal-4355	204	17	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	204	18	and	and	CCONJ
american_scientific_journal-4355	204	19	tgf	tgf	PROPN
american_scientific_journal-4355	204	20	-	-	PUNCT
american_scientific_journal-4355	204	21	β1	β1	PROPN
american_scientific_journal-4355	204	22	signalling	signal	VERB
american_scientific_journal-4355	204	23	association	association	NOUN
american_scientific_journal-4355	204	24	were	be	AUX
american_scientific_journal-4355	204	25	examined	examine	VERB
american_scientific_journal-4355	204	26	by	by	ADP
american_scientific_journal-4355	204	27	dual	dual	ADJ
american_scientific_journal-4355	204	28	luciferase	luciferase	ADJ
american_scientific_journal-4355	204	29	enzyme	enzyme	NOUN
american_scientific_journal-4355	204	30	reporter	reporter	NOUN
american_scientific_journal-4355	204	31	assay	assay	VERB
american_scientific_journal-4355	204	32	with	with	ADP
american_scientific_journal-4355	204	33	p	p	NOUN
american_scientific_journal-4355	204	34	-	-	PUNCT
american_scientific_journal-4355	204	35	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	204	36	-	-	PUNCT
american_scientific_journal-4355	204	37	β	β	NOUN
american_scientific_journal-4355	204	38	-	-	ADJ
american_scientific_journal-4355	204	39	d	d	NOUN
american_scientific_journal-4355	204	40	-	-	PUNCT
american_scientific_journal-4355	204	41	xylopyranoside	xylopyranoside	ADJ
american_scientific_journal-4355	204	42	treatment	treatment	NOUN
american_scientific_journal-4355	204	43	.	.	PUNCT
american_scientific_journal-4355	205	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	205	2	protein	protein	NOUN
american_scientific_journal-4355	205	3	was	be	AUX
american_scientific_journal-4355	205	4	down	down	ADV
american_scientific_journal-4355	205	5	regulated	regulate	VERB
american_scientific_journal-4355	205	6	as	as	SCONJ
american_scientific_journal-4355	205	7	seen	see	VERB
american_scientific_journal-4355	205	8	by	by	ADP
american_scientific_journal-4355	205	9	the	the	DET
american_scientific_journal-4355	205	10	western	western	ADJ
american_scientific_journal-4355	205	11	blotting	blot	VERB
american_scientific_journal-4355	205	12	experiment	experiment	NOUN
american_scientific_journal-4355	205	13	which	which	PRON
american_scientific_journal-4355	205	14	was	be	AUX
american_scientific_journal-4355	205	15	regulated	regulate	VERB
american_scientific_journal-4355	205	16	by	by	ADP
american_scientific_journal-4355	205	17	treatment	treatment	NOUN
american_scientific_journal-4355	205	18	with	with	ADP
american_scientific_journal-4355	205	19	p	p	NOUN
american_scientific_journal-4355	205	20	-	-	PUNCT
american_scientific_journal-4355	205	21	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	205	22	-	-	PUNCT
american_scientific_journal-4355	205	23	β	β	NOUN
american_scientific_journal-4355	205	24	-	-	PUNCT
american_scientific_journal-4355	205	25	d	d	NOUN
american_scientific_journal-4355	205	26	-	-	NOUN
american_scientific_journal-4355	205	27	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	205	28	(	(	PUNCT
american_scientific_journal-4355	205	29	figure	figure	NOUN
american_scientific_journal-4355	205	30	15	15	NUM
american_scientific_journal-4355	205	31	)	)	PUNCT
american_scientific_journal-4355	205	32	.	.	PUNCT
american_scientific_journal-4355	206	1	figure	figure	VERB
american_scientific_journal-4355	206	2	15	15	NUM
american_scientific_journal-4355	206	3	:	:	PUNCT
american_scientific_journal-4355	206	4	the	the	DET
american_scientific_journal-4355	206	5	effect	effect	NOUN
american_scientific_journal-4355	206	6	of	of	ADP
american_scientific_journal-4355	206	7	p	p	NOUN
american_scientific_journal-4355	206	8	-	-	PUNCT
american_scientific_journal-4355	206	9	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	206	10	-	-	PUNCT
american_scientific_journal-4355	206	11	β	β	NOUN
american_scientific_journal-4355	206	12	-	-	ADJ
american_scientific_journal-4355	206	13	d	d	NOUN
american_scientific_journal-4355	206	14	-	-	PUNCT
american_scientific_journal-4355	206	15	xylopyranoside	xylopyranoside	ADJ
american_scientific_journal-4355	206	16	treatment	treatment	NOUN
american_scientific_journal-4355	206	17	on	on	ADP
american_scientific_journal-4355	206	18	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	206	19	core	core	NOUN
american_scientific_journal-4355	206	20	-	-	PUNCT
american_scientific_journal-4355	206	21	protein	protein	NOUN
american_scientific_journal-4355	206	22	expression	expression	NOUN
american_scientific_journal-4355	206	23	incubation	incubation	NOUN
american_scientific_journal-4355	206	24	period	period	NOUN
american_scientific_journal-4355	206	25	of	of	ADP
american_scientific_journal-4355	206	26	p	p	NOUN
american_scientific_journal-4355	206	27	-	-	PUNCT
american_scientific_journal-4355	206	28	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	206	29	-	-	PUNCT
american_scientific_journal-4355	206	30	β	β	NOUN
american_scientific_journal-4355	206	31	-	-	PUNCT
american_scientific_journal-4355	206	32	d	d	NOUN
american_scientific_journal-4355	206	33	-	-	PUNCT
american_scientific_journal-4355	206	34	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	206	35	was	be	AUX
american_scientific_journal-4355	206	36	72	72	NUM
american_scientific_journal-4355	206	37	hours	hour	NOUN
american_scientific_journal-4355	206	38	.	.	PUNCT
american_scientific_journal-4355	207	1	the	the	DET
american_scientific_journal-4355	207	2	effect	effect	NOUN
american_scientific_journal-4355	207	3	of	of	ADP
american_scientific_journal-4355	207	4	p	p	NOUN
american_scientific_journal-4355	207	5	-	-	PUNCT
american_scientific_journal-4355	207	6	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	207	7	-	-	PUNCT
american_scientific_journal-4355	207	8	β	β	NOUN
american_scientific_journal-4355	207	9	-	-	ADJ
american_scientific_journal-4355	207	10	d	d	ADJ
american_scientific_journal-4355	207	11	-	-	PUNCT
american_scientific_journal-4355	207	12	xylopyranoside	xylopyranoside	ADJ
american_scientific_journal-4355	207	13	treatment	treatment	NOUN
american_scientific_journal-4355	207	14	(	(	PUNCT
american_scientific_journal-4355	207	15	the	the	DET
american_scientific_journal-4355	207	16	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	207	17	functional	functional	ADJ
american_scientific_journal-4355	207	18	part	part	NOUN
american_scientific_journal-4355	207	19	inhibitor	inhibitor	NOUN
american_scientific_journal-4355	207	20	,	,	PUNCT
american_scientific_journal-4355	207	21	heparan	heparan	ADJ
american_scientific_journal-4355	207	22	sulphate	sulphate	NOUN
american_scientific_journal-4355	207	23	)	)	PUNCT
american_scientific_journal-4355	207	24	,	,	PUNCT
american_scientific_journal-4355	207	25	as	as	SCONJ
american_scientific_journal-4355	207	26	it	it	PRON
american_scientific_journal-4355	207	27	affects	affect	VERB
american_scientific_journal-4355	207	28	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	207	29	protein	protein	NOUN
american_scientific_journal-4355	207	30	expression	expression	NOUN
american_scientific_journal-4355	207	31	,	,	PUNCT
american_scientific_journal-4355	207	32	results	result	NOUN
american_scientific_journal-4355	207	33	assayed	assayed	ADJ
american_scientific_journal-4355	207	34	with	with	ADP
american_scientific_journal-4355	207	35	gapdh	gapdh	NOUN
american_scientific_journal-4355	207	36	.	.	PUNCT
american_scientific_journal-4355	208	1	high	high	ADJ
american_scientific_journal-4355	208	2	molecular	molecular	ADJ
american_scientific_journal-4355	208	3	weight	weight	NOUN
american_scientific_journal-4355	208	4	ladder	ladder	NOUN
american_scientific_journal-4355	208	5	was	be	AUX
american_scientific_journal-4355	208	6	used	use	VERB
american_scientific_journal-4355	208	7	to	to	PART
american_scientific_journal-4355	208	8	visualize	visualize	VERB
american_scientific_journal-4355	208	9	the	the	DET
american_scientific_journal-4355	208	10	high	high	ADJ
american_scientific_journal-4355	208	11	molecular	molecular	ADJ
american_scientific_journal-4355	208	12	weight	weight	NOUN
american_scientific_journal-4355	208	13	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	208	14	size	size	NOUN
american_scientific_journal-4355	208	15	.	.	PUNCT
american_scientific_journal-4355	209	1	this	this	DET
american_scientific_journal-4355	209	2	experiment	experiment	NOUN
american_scientific_journal-4355	209	3	was	be	AUX
american_scientific_journal-4355	209	4	repeated	repeat	VERB
american_scientific_journal-4355	209	5	3	3	NUM
american_scientific_journal-4355	209	6	times	time	NOUN
american_scientific_journal-4355	209	7	and	and	CCONJ
american_scientific_journal-4355	209	8	gave	give	VERB
american_scientific_journal-4355	209	9	the	the	DET
american_scientific_journal-4355	209	10	same	same	ADJ
american_scientific_journal-4355	209	11	result	result	NOUN
american_scientific_journal-4355	209	12	.	.	PUNCT
american_scientific_journal-4355	210	1	t	t	PROPN
american_scientific_journal-4355	210	2	=	=	SYM
american_scientific_journal-4355	210	3	tgf	tgf	PROPN
american_scientific_journal-4355	210	4	-	-	PUNCT
american_scientific_journal-4355	210	5	β	β	PROPN
american_scientific_journal-4355	210	6	,	,	PUNCT
american_scientific_journal-4355	210	7	xt	xt	PUNCT
american_scientific_journal-4355	211	1	=	=	SYM
american_scientific_journal-4355	211	2	p	p	X
american_scientific_journal-4355	211	3	-	-	PUNCT
american_scientific_journal-4355	211	4	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	211	5	-	-	PUNCT
american_scientific_journal-4355	211	6	β	β	NOUN
american_scientific_journal-4355	211	7	-	-	PUNCT
american_scientific_journal-4355	211	8	d	d	NOUN
american_scientific_journal-4355	211	9	-	-	PUNCT
american_scientific_journal-4355	211	10	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	211	11	+	+	CCONJ
american_scientific_journal-4355	211	12	tgf	tgf	PROPN
american_scientific_journal-4355	211	13	-	-	PUNCT
american_scientific_journal-4355	211	14	β	β	NOUN
american_scientific_journal-4355	211	15	.	.	PROPN
american_scientific_journal-4355	212	1	2.13	2.13	NUM
american_scientific_journal-4355	212	2	.	.	PUNCT
american_scientific_journal-4355	212	3	effect	effect	NOUN
american_scientific_journal-4355	212	4	of	of	ADP
american_scientific_journal-4355	212	5	p	p	NOUN
american_scientific_journal-4355	212	6	-	-	PUNCT
american_scientific_journal-4355	212	7	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	212	8	-	-	PUNCT
american_scientific_journal-4355	212	9	β	β	NOUN
american_scientific_journal-4355	212	10	-	-	ADJ
american_scientific_journal-4355	212	11	d	d	NOUN
american_scientific_journal-4355	212	12	-	-	PUNCT
american_scientific_journal-4355	212	13	xylopyranoside	xylopyranoside	ADJ
american_scientific_journal-4355	212	14	treatment	treatment	NOUN
american_scientific_journal-4355	212	15	on	on	ADP
american_scientific_journal-4355	212	16	p	p	NOUN
american_scientific_journal-4355	212	17	-	-	PUNCT
american_scientific_journal-4355	212	18	smad	smad	VERB
american_scientific_journal-4355	212	19	-	-	PUNCT
american_scientific_journal-4355	212	20	iii	iii	NOUN
american_scientific_journal-4355	212	21	the	the	DET
american_scientific_journal-4355	212	22	purpose	purpose	NOUN
american_scientific_journal-4355	212	23	of	of	ADP
american_scientific_journal-4355	212	24	this	this	DET
american_scientific_journal-4355	212	25	experiment	experiment	NOUN
american_scientific_journal-4355	212	26	was	be	AUX
american_scientific_journal-4355	212	27	to	to	PART
american_scientific_journal-4355	212	28	show	show	VERB
american_scientific_journal-4355	212	29	how	how	SCONJ
american_scientific_journal-4355	212	30	p	p	ADJ
american_scientific_journal-4355	212	31	-	-	PUNCT
american_scientific_journal-4355	212	32	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	212	33	-	-	PUNCT
american_scientific_journal-4355	212	34	β	β	NOUN
american_scientific_journal-4355	212	35	-	-	PUNCT
american_scientific_journal-4355	212	36	d	d	NOUN
american_scientific_journal-4355	212	37	-	-	PUNCT
american_scientific_journal-4355	212	38	xylopyranoside	xylopyranoside	PROPN
american_scientific_journal-4355	212	39	was	be	AUX
american_scientific_journal-4355	212	40	affected	affect	VERB
american_scientific_journal-4355	212	41	tgf	tgf	PROPN
american_scientific_journal-4355	212	42	-	-	PUNCT
american_scientific_journal-4355	212	43	β	β	NOUN
american_scientific_journal-4355	212	44	core	core	NOUN
american_scientific_journal-4355	212	45	-	-	PUNCT
american_scientific_journal-4355	212	46	protein	protein	NOUN
american_scientific_journal-4355	212	47	(	(	PUNCT
american_scientific_journal-4355	212	48	the	the	DET
american_scientific_journal-4355	212	49	p	p	NOUN
american_scientific_journal-4355	212	50	-	-	PUNCT
american_scientific_journal-4355	212	51	smad	smad	VERB
american_scientific_journal-4355	212	52	-	-	PUNCT
american_scientific_journal-4355	212	53	iii	iii	NOUN
american_scientific_journal-4355	212	54	)	)	PUNCT
american_scientific_journal-4355	212	55	which	which	PRON
american_scientific_journal-4355	212	56	was	be	AUX
american_scientific_journal-4355	212	57	visualised	visualise	VERB
american_scientific_journal-4355	212	58	by	by	ADP
american_scientific_journal-4355	212	59	western	western	ADJ
american_scientific_journal-4355	212	60	blotting	blotting	NOUN
american_scientific_journal-4355	212	61	.	.	PUNCT
american_scientific_journal-4355	213	1	after	after	ADP
american_scientific_journal-4355	213	2	transfection	transfection	NOUN
american_scientific_journal-4355	213	3	of	of	ADP
american_scientific_journal-4355	213	4	hk2	hk2	NOUN
american_scientific_journal-4355	213	5	cells	cell	NOUN
american_scientific_journal-4355	213	6	with	with	ADP
american_scientific_journal-4355	213	7	p	p	NOUN
american_scientific_journal-4355	213	8	-	-	PUNCT
american_scientific_journal-4355	213	9	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	213	10	-	-	PUNCT
american_scientific_journal-4355	213	11	β	β	NOUN
american_scientific_journal-4355	213	12	-	-	ADJ
american_scientific_journal-4355	213	13	d	d	NOUN
american_scientific_journal-4355	213	14	-	-	PUNCT
american_scientific_journal-4355	213	15	xylopyranoside	xylopyranoside	ADJ
american_scientific_journal-4355	213	16	treatment	treatment	NOUN
american_scientific_journal-4355	213	17	,	,	PUNCT
american_scientific_journal-4355	213	18	stimulation	stimulation	NOUN
american_scientific_journal-4355	213	19	with	with	ADP
american_scientific_journal-4355	213	20	tgf	tgf	PROPN
american_scientific_journal-4355	213	21	-	-	PUNCT
american_scientific_journal-4355	213	22	β	β	PROPN
american_scientific_journal-4355	213	23	was	be	AUX
american_scientific_journal-4355	213	24	done	do	VERB
american_scientific_journal-4355	213	25	at	at	ADP
american_scientific_journal-4355	213	26	15	15	NUM
american_scientific_journal-4355	213	27	,	,	PUNCT
american_scientific_journal-4355	213	28	30	30	NUM
american_scientific_journal-4355	213	29	,	,	PUNCT
american_scientific_journal-4355	213	30	60	60	NUM
american_scientific_journal-4355	213	31	and	and	CCONJ
american_scientific_journal-4355	213	32	120	120	NUM
american_scientific_journal-4355	213	33	minutes	minute	NOUN
american_scientific_journal-4355	213	34	then	then	ADV
american_scientific_journal-4355	213	35	scraping	scrape	VERB
american_scientific_journal-4355	213	36	of	of	ADP
american_scientific_journal-4355	213	37	the	the	DET
american_scientific_journal-4355	213	38	protein	protein	NOUN
american_scientific_journal-4355	213	39	and	and	CCONJ
american_scientific_journal-4355	213	40	proceeding	proceeding	NOUN
american_scientific_journal-4355	213	41	to	to	ADP
american_scientific_journal-4355	213	42	sds	sds	NOUN
american_scientific_journal-4355	213	43	-	-	PUNCT
american_scientific_journal-4355	213	44	page	page	NOUN
american_scientific_journal-4355	213	45	and	and	CCONJ
american_scientific_journal-4355	213	46	western	western	ADJ
american_scientific_journal-4355	213	47	blotting	blotting	NOUN
american_scientific_journal-4355	213	48	as	as	SCONJ
american_scientific_journal-4355	213	49	described	describe	VERB
american_scientific_journal-4355	213	50	in	in	ADP
american_scientific_journal-4355	213	51	the	the	DET
american_scientific_journal-4355	213	52	methods	method	NOUN
american_scientific_journal-4355	213	53	(	(	PUNCT
american_scientific_journal-4355	213	54	section	section	NOUN
american_scientific_journal-4355	213	55	2.11	2.11	NUM
american_scientific_journal-4355	213	56	)	)	PUNCT
american_scientific_journal-4355	213	57	,	,	PUNCT
american_scientific_journal-4355	213	58	which	which	PRON
american_scientific_journal-4355	213	59	revealed	reveal	VERB
american_scientific_journal-4355	213	60	a	a	DET
american_scientific_journal-4355	213	61	significant	significant	ADJ
american_scientific_journal-4355	213	62	change	change	NOUN
american_scientific_journal-4355	213	63	of	of	ADP
american_scientific_journal-4355	213	64	p	p	NOUN
american_scientific_journal-4355	213	65	-	-	PUNCT
american_scientific_journal-4355	213	66	smad	smad	VERB
american_scientific_journal-4355	213	67	-	-	PUNCT
american_scientific_journal-4355	213	68	iii	iii	NUM
american_scientific_journal-4355	213	69	phosphorylation	phosphorylation	NOUN
american_scientific_journal-4355	213	70	,	,	PUNCT
american_scientific_journal-4355	213	71	results	result	NOUN
american_scientific_journal-4355	213	72	assayed	assay	VERB
american_scientific_journal-4355	213	73	by	by	ADP
american_scientific_journal-4355	213	74	gapdh	gapdh	NOUN
american_scientific_journal-4355	213	75	,	,	PUNCT
american_scientific_journal-4355	213	76	and	and	CCONJ
american_scientific_journal-4355	213	77	here	here	ADV
american_scientific_journal-4355	213	78	supports	support	VERB
american_scientific_journal-4355	213	79	that	that	SCONJ
american_scientific_journal-4355	213	80	p	p	NOUN
american_scientific_journal-4355	213	81	-	-	PUNCT
american_scientific_journal-4355	213	82	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	213	83	-	-	PUNCT
american_scientific_journal-4355	213	84	β	β	NOUN
american_scientific_journal-4355	213	85	-	-	PUNCT
american_scientific_journal-4355	213	86	d	d	NOUN
american_scientific_journal-4355	213	87	-	-	NOUN
american_scientific_journal-4355	213	88	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	213	89	through	through	ADP
american_scientific_journal-4355	213	90	inhibition	inhibition	NOUN
american_scientific_journal-4355	213	91	of	of	ADP
american_scientific_journal-4355	213	92	heparan	heparan	ADJ
american_scientific_journal-4355	213	93	sulphate	sulphate	NOUN
american_scientific_journal-4355	213	94	,	,	PUNCT
american_scientific_journal-4355	213	95	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	213	96	core	core	NOUN
american_scientific_journal-4355	213	97	protein	protein	NOUN
american_scientific_journal-4355	213	98	and	and	CCONJ
american_scientific_journal-4355	213	99	subsequently	subsequently	ADV
american_scientific_journal-4355	213	100	tgf	tgf	PROPN
american_scientific_journal-4355	213	101	-	-	PUNCT
american_scientific_journal-4355	213	102	β	β	PROPN
american_scientific_journal-4355	213	103	found	find	VERB
american_scientific_journal-4355	213	104	to	to	PART
american_scientific_journal-4355	213	105	be	be	AUX
american_scientific_journal-4355	213	106	down	down	ADV
american_scientific_journal-4355	213	107	regulated	regulate	VERB
american_scientific_journal-4355	213	108	[	[	PUNCT
american_scientific_journal-4355	213	109	45	45	NUM
american_scientific_journal-4355	213	110	]	]	PUNCT
american_scientific_journal-4355	213	111	,	,	PUNCT
american_scientific_journal-4355	213	112	as	as	SCONJ
american_scientific_journal-4355	213	113	shown	show	VERB
american_scientific_journal-4355	213	114	in	in	ADP
american_scientific_journal-4355	213	115	(	(	PUNCT
american_scientific_journal-4355	213	116	figure	figure	NOUN
american_scientific_journal-4355	213	117	16	16	NUM
american_scientific_journal-4355	213	118	)	)	PUNCT
american_scientific_journal-4355	213	119	.	.	PUNCT
american_scientific_journal-4355	214	1	figure	figure	VERB
american_scientific_journal-4355	214	2	16	16	NUM
american_scientific_journal-4355	214	3	:	:	PUNCT
american_scientific_journal-4355	214	4	effect	effect	NOUN
american_scientific_journal-4355	214	5	of	of	ADP
american_scientific_journal-4355	214	6	p	p	NOUN
american_scientific_journal-4355	214	7	-	-	PUNCT
american_scientific_journal-4355	214	8	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	214	9	-	-	PUNCT
american_scientific_journal-4355	214	10	β	β	NOUN
american_scientific_journal-4355	214	11	-	-	ADJ
american_scientific_journal-4355	214	12	d	d	NOUN
american_scientific_journal-4355	214	13	-	-	PUNCT
american_scientific_journal-4355	214	14	xylopyranoside	xylopyranoside	ADJ
american_scientific_journal-4355	214	15	treatment	treatment	NOUN
american_scientific_journal-4355	214	16	on	on	ADP
american_scientific_journal-4355	214	17	p	p	NOUN
american_scientific_journal-4355	214	18	-	-	PUNCT
american_scientific_journal-4355	214	19	smad	smad	VERB
american_scientific_journal-4355	214	20	-	-	PUNCT
american_scientific_journal-4355	214	21	iii	iii	NUM
american_scientific_journal-4355	214	22	2.14	2.14	NUM
american_scientific_journal-4355	214	23	.	.	PUNCT
american_scientific_journal-4355	215	1	the	the	DET
american_scientific_journal-4355	215	2	function	function	NOUN
american_scientific_journal-4355	215	3	of	of	ADP
american_scientific_journal-4355	215	4	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	215	5	the	the	DET
american_scientific_journal-4355	215	6	potential	potential	ADJ
american_scientific_journal-4355	215	7	impact	impact	NOUN
american_scientific_journal-4355	215	8	of	of	ADP
american_scientific_journal-4355	215	9	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	215	10	as	as	ADP
american_scientific_journal-4355	215	11	a	a	DET
american_scientific_journal-4355	215	12	marker	marker	NOUN
american_scientific_journal-4355	215	13	of	of	ADP
american_scientific_journal-4355	215	14	epithelium	epithelium	NOUN
american_scientific_journal-4355	215	15	(	(	PUNCT
american_scientific_journal-4355	215	16	e	e	NOUN
american_scientific_journal-4355	215	17	-	-	NOUN
american_scientific_journal-4355	215	18	cadherin	cadherin	NOUN
american_scientific_journal-4355	215	19	)	)	PUNCT
american_scientific_journal-4355	215	20	or	or	CCONJ
american_scientific_journal-4355	215	21	mesenchymal	mesenchymal	NOUN
american_scientific_journal-4355	215	22	cells	cell	NOUN
american_scientific_journal-4355	215	23	(	(	PUNCT
american_scientific_journal-4355	215	24	α	α	NOUN
american_scientific_journal-4355	215	25	-	-	PUNCT
american_scientific_journal-4355	215	26	sma	sma	NOUN
american_scientific_journal-4355	215	27	)	)	PUNCT
american_scientific_journal-4355	215	28	is	be	AUX
american_scientific_journal-4355	215	29	studied	study	VERB
american_scientific_journal-4355	215	30	in	in	ADP
american_scientific_journal-4355	215	31	this	this	DET
american_scientific_journal-4355	215	32	chapter	chapter	NOUN
american_scientific_journal-4355	215	33	.	.	PUNCT
american_scientific_journal-4355	216	1	cadherins	cadherin	NOUN
american_scientific_journal-4355	216	2	are	be	AUX
american_scientific_journal-4355	216	3	calcium	calcium	NOUN
american_scientific_journal-4355	216	4	-	-	PUNCT
american_scientific_journal-4355	216	5	dependent	dependent	ADJ
american_scientific_journal-4355	216	6	adhesion	adhesion	NOUN
american_scientific_journal-4355	216	7	molecules	molecule	NOUN
american_scientific_journal-4355	216	8	and	and	CCONJ
american_scientific_journal-4355	216	9	members	member	NOUN
american_scientific_journal-4355	216	10	of	of	ADP
american_scientific_journal-4355	216	11	a	a	DET
american_scientific_journal-4355	216	12	class	class	NOUN
american_scientific_journal-4355	216	13	of	of	ADP
american_scientific_journal-4355	216	14	type-1	type-1	NUM
american_scientific_journal-4355	216	15	transmembrane	transmembrane	ADJ
american_scientific_journal-4355	216	16	proteins	protein	NOUN
american_scientific_journal-4355	216	17	.	.	PUNCT
american_scientific_journal-4355	217	1	they	they	PRON
american_scientific_journal-4355	217	2	have	have	VERB
american_scientific_journal-4355	217	3	important	important	ADJ
american_scientific_journal-4355	217	4	roles	role	NOUN
american_scientific_journal-4355	217	5	in	in	ADP
american_scientific_journal-4355	217	6	cell	cell	NOUN
american_scientific_journal-4355	217	7	adhesion	adhesion	NOUN
american_scientific_journal-4355	217	8	and	and	CCONJ
american_scientific_journal-4355	217	9	contribute	contribute	VERB
american_scientific_journal-4355	217	10	to	to	ADP
american_scientific_journal-4355	217	11	mechanisms	mechanism	NOUN
american_scientific_journal-4355	217	12	controlling	control	VERB
american_scientific_journal-4355	217	13	how	how	SCONJ
american_scientific_journal-4355	217	14	cells	cell	NOUN
american_scientific_journal-4355	217	15	within	within	ADP
american_scientific_journal-4355	217	16	tissues	tissue	NOUN
american_scientific_journal-4355	217	17	are	be	AUX
american_scientific_journal-4355	217	18	bound	bind	VERB
american_scientific_journal-4355	217	19	together	together	ADV
american_scientific_journal-4355	217	20	.	.	PUNCT
american_scientific_journal-4355	218	1	the	the	DET
american_scientific_journal-4355	218	2	cadherin	cadherin	NOUN
american_scientific_journal-4355	218	3	superfamily	superfamily	ADV
american_scientific_journal-4355	218	4	includes	include	VERB
american_scientific_journal-4355	218	5	cadherins	cadherin	NOUN
american_scientific_journal-4355	218	6	,	,	PUNCT
american_scientific_journal-4355	218	7	protocadherins	protocadherin	NOUN
american_scientific_journal-4355	218	8	,	,	PUNCT
american_scientific_journal-4355	218	9	desmogleins	desmoglein	NOUN
american_scientific_journal-4355	218	10	,	,	PUNCT
american_scientific_journal-4355	218	11	and	and	CCONJ
american_scientific_journal-4355	218	12	desmocollins	desmocollin	NOUN
american_scientific_journal-4355	218	13	.	.	PUNCT
american_scientific_journal-4355	219	1	in	in	ADP
american_scientific_journal-4355	219	2	structure	structure	NOUN
american_scientific_journal-4355	219	3	,	,	PUNCT
american_scientific_journal-4355	219	4	they	they	PRON
american_scientific_journal-4355	219	5	share	share	VERB
american_scientific_journal-4355	219	6	cadherin	cadherin	NOUN
american_scientific_journal-4355	219	7	repeats	repeat	NOUN
american_scientific_journal-4355	219	8	,	,	PUNCT
american_scientific_journal-4355	219	9	which	which	PRON
american_scientific_journal-4355	219	10	are	be	AUX
american_scientific_journal-4355	219	11	the	the	DET
american_scientific_journal-4355	219	12	extracellular	extracellular	ADJ
american_scientific_journal-4355	219	13	ca2	ca2	PROPN
american_scientific_journal-4355	219	14	+	+	ADJ
american_scientific_journal-4355	219	15	-binding	-binding	ADJ
american_scientific_journal-4355	219	16	domains	domain	NOUN
american_scientific_journal-4355	219	17	[	[	X
american_scientific_journal-4355	219	18	46	46	NUM
american_scientific_journal-4355	219	19	]	]	PUNCT
american_scientific_journal-4355	219	20	,	,	PUNCT
american_scientific_journal-4355	219	21	loss	loss	NOUN
american_scientific_journal-4355	219	22	of	of	ADP
american_scientific_journal-4355	219	23	both	both	DET
american_scientific_journal-4355	219	24	e	e	NOUN
american_scientific_journal-4355	219	25	-	-	NOUN
american_scientific_journal-4355	219	26	cadherin	cadherin	NOUN
american_scientific_journal-4355	219	27	expression	expression	NOUN
american_scientific_journal-4355	219	28	and	and	CCONJ
american_scientific_journal-4355	219	29	function	function	NOUN
american_scientific_journal-4355	219	30	,	,	PUNCT
american_scientific_journal-4355	219	31	has	have	AUX
american_scientific_journal-4355	219	32	been	be	AUX
american_scientific_journal-4355	219	33	implicated	implicate	VERB
american_scientific_journal-4355	219	34	in	in	ADP
american_scientific_journal-4355	219	35	cancer	cancer	NOUN
american_scientific_journal-4355	219	36	progression	progression	NOUN
american_scientific_journal-4355	219	37	and	and	CCONJ
american_scientific_journal-4355	219	38	metastasis	metastasis	NOUN
american_scientific_journal-4355	219	39	.	.	PUNCT
american_scientific_journal-4355	220	1	e	e	X
american_scientific_journal-4355	220	2	-	-	NOUN
american_scientific_journal-4355	220	3	cadherin	cadherin	NOUN
american_scientific_journal-4355	220	4	down	down	ADP
american_scientific_journal-4355	220	5	-	-	PUNCT
american_scientific_journal-4355	220	6	regulation	regulation	NOUN
american_scientific_journal-4355	220	7	decreases	decrease	VERB
american_scientific_journal-4355	220	8	the	the	DET
american_scientific_journal-4355	220	9	strength	strength	NOUN
american_scientific_journal-4355	220	10	of	of	ADP
american_scientific_journal-4355	220	11	cellular	cellular	ADJ
american_scientific_journal-4355	220	12	adhesion	adhesion	NOUN
american_scientific_journal-4355	220	13	within	within	ADP
american_scientific_journal-4355	220	14	a	a	DET
american_scientific_journal-4355	220	15	tissue	tissue	NOUN
american_scientific_journal-4355	220	16	,	,	PUNCT
american_scientific_journal-4355	220	17	resulting	result	VERB
american_scientific_journal-4355	220	18	in	in	ADP
american_scientific_journal-4355	220	19	an	an	DET
american_scientific_journal-4355	220	20	increase	increase	NOUN
american_scientific_journal-4355	220	21	in	in	ADP
american_scientific_journal-4355	220	22	cellular	cellular	ADJ
american_scientific_journal-4355	220	23	motility	motility	NOUN
american_scientific_journal-4355	220	24	.	.	PUNCT
american_scientific_journal-4355	221	1	this	this	PRON
american_scientific_journal-4355	221	2	in	in	ADP
american_scientific_journal-4355	221	3	turn	turn	NOUN
american_scientific_journal-4355	221	4	may	may	AUX
american_scientific_journal-4355	221	5	allow	allow	VERB
american_scientific_journal-4355	221	6	cancer	cancer	NOUN
american_scientific_journal-4355	221	7	cells	cell	NOUN
american_scientific_journal-4355	221	8	to	to	PART
american_scientific_journal-4355	221	9	cross	cross	VERB
american_scientific_journal-4355	221	10	the	the	DET
american_scientific_journal-4355	221	11	basement	basement	NOUN
american_scientific_journal-4355	221	12	membrane	membrane	NOUN
american_scientific_journal-4355	221	13	and	and	CCONJ
american_scientific_journal-4355	221	14	invade	invade	VERB
american_scientific_journal-4355	221	15	surrounding	surround	VERB
american_scientific_journal-4355	221	16	tissues.actin	tissues.actin	NOUN
american_scientific_journal-4355	221	17	is	be	AUX
american_scientific_journal-4355	221	18	the	the	DET
american_scientific_journal-4355	221	19	monomeric	monomeric	ADJ
american_scientific_journal-4355	221	20	subunit	subunit	NOUN
american_scientific_journal-4355	221	21	of	of	ADP
american_scientific_journal-4355	221	22	two	two	NUM
american_scientific_journal-4355	221	23	types	type	NOUN
american_scientific_journal-4355	221	24	of	of	ADP
american_scientific_journal-4355	221	25	filaments	filament	NOUN
american_scientific_journal-4355	221	26	in	in	ADP
american_scientific_journal-4355	221	27	cells	cell	NOUN
american_scientific_journal-4355	221	28	:	:	PUNCT
american_scientific_journal-4355	221	29	microfilaments	microfilament	NOUN
american_scientific_journal-4355	221	30	,	,	PUNCT
american_scientific_journal-4355	221	31	one	one	NUM
american_scientific_journal-4355	221	32	of	of	ADP
american_scientific_journal-4355	221	33	the	the	DET
american_scientific_journal-4355	221	34	three	three	NUM
american_scientific_journal-4355	221	35	major	major	ADJ
american_scientific_journal-4355	221	36	components	component	NOUN
american_scientific_journal-4355	221	37	of	of	ADP
american_scientific_journal-4355	221	38	the	the	DET
american_scientific_journal-4355	221	39	cytoskeleton	cytoskeleton	NOUN
american_scientific_journal-4355	221	40	,	,	PUNCT
american_scientific_journal-4355	221	41	and	and	CCONJ
american_scientific_journal-4355	221	42	thin	thin	ADJ
american_scientific_journal-4355	221	43	filaments	filament	NOUN
american_scientific_journal-4355	221	44	,	,	PUNCT
american_scientific_journal-4355	221	45	part	part	NOUN
american_scientific_journal-4355	221	46	of	of	ADP
american_scientific_journal-4355	221	47	the	the	DET
american_scientific_journal-4355	221	48	contractile	contractile	NOUN
american_scientific_journal-4355	221	49	apparatus	apparatus	NOUN
american_scientific_journal-4355	221	50	in	in	ADP
american_scientific_journal-4355	221	51	muscle	muscle	NOUN
american_scientific_journal-4355	221	52	cells	cell	NOUN
american_scientific_journal-4355	221	53	.	.	PUNCT
american_scientific_journal-4355	222	1	thus	thus	ADV
american_scientific_journal-4355	222	2	,	,	PUNCT
american_scientific_journal-4355	222	3	actin	actin	NOUN
american_scientific_journal-4355	222	4	participates	participate	VERB
american_scientific_journal-4355	222	5	in	in	ADP
american_scientific_journal-4355	222	6	many	many	ADJ
american_scientific_journal-4355	222	7	important	important	ADJ
american_scientific_journal-4355	222	8	cellular	cellular	ADJ
american_scientific_journal-4355	222	9	processes	process	NOUN
american_scientific_journal-4355	222	10	including	include	VERB
american_scientific_journal-4355	222	11	muscle	muscle	NOUN
american_scientific_journal-4355	222	12	contraction	contraction	NOUN
american_scientific_journal-4355	222	13	,	,	PUNCT
american_scientific_journal-4355	222	14	cell	cell	NOUN
american_scientific_journal-4355	222	15	motility	motility	NOUN
american_scientific_journal-4355	222	16	,	,	PUNCT
american_scientific_journal-4355	222	17	cell	cell	NOUN
american_scientific_journal-4355	222	18	division	division	NOUN
american_scientific_journal-4355	222	19	and	and	CCONJ
american_scientific_journal-4355	222	20	cytokinesis	cytokinesis	NOUN
american_scientific_journal-4355	222	21	,	,	PUNCT
american_scientific_journal-4355	222	22	vesicle	vesicle	NOUN
american_scientific_journal-4355	222	23	and	and	CCONJ
american_scientific_journal-4355	222	24	organelle	organelle	NOUN
american_scientific_journal-4355	222	25	movement	movement	NOUN
american_scientific_journal-4355	222	26	,	,	PUNCT
american_scientific_journal-4355	222	27	cell	cell	NOUN
american_scientific_journal-4355	222	28	signalling	signalling	NOUN
american_scientific_journal-4355	222	29	,	,	PUNCT
american_scientific_journal-4355	222	30	and	and	CCONJ
american_scientific_journal-4355	222	31	the	the	DET
american_scientific_journal-4355	222	32	establishment	establishment	NOUN
american_scientific_journal-4355	222	33	and	and	CCONJ
american_scientific_journal-4355	222	34	maintenance	maintenance	NOUN
american_scientific_journal-4355	222	35	of	of	ADP
american_scientific_journal-4355	222	36	cell	cell	NOUN
american_scientific_journal-4355	222	37	junctions	junction	NOUN
american_scientific_journal-4355	222	38	and	and	CCONJ
american_scientific_journal-4355	222	39	cell	cell	NOUN
american_scientific_journal-4355	222	40	line	line	NOUN
american_scientific_journal-4355	222	41	.	.	PUNCT
american_scientific_journal-4355	223	1	alpha	alpha	PROPN
american_scientific_journal-4355	223	2	smooth	smooth	ADJ
american_scientific_journal-4355	223	3	muscle	muscle	NOUN
american_scientific_journal-4355	223	4	actin	actin	NOUN
american_scientific_journal-4355	223	5	is	be	AUX
american_scientific_journal-4355	223	6	a	a	DET
american_scientific_journal-4355	223	7	protein	protein	NOUN
american_scientific_journal-4355	223	8	that	that	PRON
american_scientific_journal-4355	223	9	in	in	ADP
american_scientific_journal-4355	223	10	humans	human	NOUN
american_scientific_journal-4355	223	11	is	be	AUX
american_scientific_journal-4355	223	12	encoded	encode	VERB
american_scientific_journal-4355	223	13	by	by	ADP
american_scientific_journal-4355	223	14	the	the	DET
american_scientific_journal-4355	223	15	acta2	acta2	NOUN
american_scientific_journal-4355	223	16	gene	gene	NOUN
american_scientific_journal-4355	223	17	located	locate	VERB
american_scientific_journal-4355	223	18	on	on	ADP
american_scientific_journal-4355	223	19	10q22	10q22	NUM
american_scientific_journal-4355	223	20	-	-	PUNCT
american_scientific_journal-4355	223	21	q24	q24	NOUN
american_scientific_journal-4355	223	22	[	[	X
american_scientific_journal-4355	223	23	47	47	NUM
american_scientific_journal-4355	223	24	]	]	PUNCT
american_scientific_journal-4355	223	25	.	.	PUNCT
american_scientific_journal-4355	224	1	the	the	DET
american_scientific_journal-4355	224	2	alpha	alpha	PROPN
american_scientific_journal-4355	224	3	smooth	smooth	PROPN
american_scientific_journal-4355	224	4	actin	actin	NOUN
american_scientific_journal-4355	224	5	is	be	AUX
american_scientific_journal-4355	224	6	found	find	VERB
american_scientific_journal-4355	224	7	in	in	ADP
american_scientific_journal-4355	224	8	muscle	muscle	NOUN
american_scientific_journal-4355	224	9	tissues	tissue	NOUN
american_scientific_journal-4355	224	10	and	and	CCONJ
american_scientific_journal-4355	224	11	is	be	AUX
american_scientific_journal-4355	224	12	a	a	DET
american_scientific_journal-4355	224	13	major	major	ADJ
american_scientific_journal-4355	224	14	constituent	constituent	NOUN
american_scientific_journal-4355	224	15	of	of	ADP
american_scientific_journal-4355	224	16	the	the	DET
american_scientific_journal-4355	224	17	contractile	contractile	NOUN
american_scientific_journal-4355	224	18	apparatus[48	apparatus[48	NOUN
american_scientific_journal-4355	224	19	]	]	PUNCT
american_scientific_journal-4355	224	20	.	.	PUNCT
american_scientific_journal-4355	225	1	it	it	PRON
american_scientific_journal-4355	225	2	can	can	AUX
american_scientific_journal-4355	225	3	be	be	AUX
american_scientific_journal-4355	225	4	used	use	VERB
american_scientific_journal-4355	225	5	for	for	ADP
american_scientific_journal-4355	225	6	evaluation	evaluation	NOUN
american_scientific_journal-4355	225	7	of	of	ADP
american_scientific_journal-4355	225	8	the	the	DET
american_scientific_journal-4355	225	9	disease	disease	NOUN
american_scientific_journal-4355	225	10	activity	activity	NOUN
american_scientific_journal-4355	225	11	and	and	CCONJ
american_scientific_journal-4355	225	12	prognosis	prognosis	NOUN
american_scientific_journal-4355	225	13	as	as	ADP
american_scientific_journal-4355	225	14	its	its	PRON
american_scientific_journal-4355	225	15	expression	expression	NOUN
american_scientific_journal-4355	225	16	increased	increase	VERB
american_scientific_journal-4355	225	17	by	by	ADP
american_scientific_journal-4355	225	18	mesangial	mesangial	ADJ
american_scientific_journal-4355	225	19	cells	cell	NOUN
american_scientific_journal-4355	225	20	from	from	ADP
american_scientific_journal-4355	225	21	gn	gn	PROPN
american_scientific_journal-4355	225	22	patients	patient	NOUN
american_scientific_journal-4355	225	23	in	in	ADP
american_scientific_journal-4355	225	24	the	the	DET
american_scientific_journal-4355	225	25	kidneys	kidney	NOUN
american_scientific_journal-4355	225	26	[	[	X
american_scientific_journal-4355	225	27	49	49	NUM
american_scientific_journal-4355	225	28	]	]	PUNCT
american_scientific_journal-4355	225	29	.	.	PUNCT
american_scientific_journal-4355	226	1	the	the	DET
american_scientific_journal-4355	226	2	expression	expression	NOUN
american_scientific_journal-4355	226	3	of	of	ADP
american_scientific_journal-4355	226	4	α	α	NOUN
american_scientific_journal-4355	226	5	-	-	ADJ
american_scientific_journal-4355	226	6	smooth	smooth	ADJ
american_scientific_journal-4355	226	7	muscle	muscle	NOUN
american_scientific_journal-4355	226	8	action	action	NOUN
american_scientific_journal-4355	226	9	(	(	PUNCT
american_scientific_journal-4355	226	10	α	α	NOUN
american_scientific_journal-4355	226	11	-	-	PUNCT
american_scientific_journal-4355	226	12	sma	sma	NOUN
american_scientific_journal-4355	226	13	)	)	PUNCT
american_scientific_journal-4355	226	14	in	in	ADP
american_scientific_journal-4355	226	15	the	the	DET
american_scientific_journal-4355	226	16	renal	renal	ADJ
american_scientific_journal-4355	226	17	tubulointerstitium	tubulointerstitium	NOUN
american_scientific_journal-4355	226	18	in	in	ADP
american_scientific_journal-4355	226	19	patients	patient	NOUN
american_scientific_journal-4355	226	20	with	with	ADP
american_scientific_journal-4355	226	21	kidney	kidney	NOUN
american_scientific_journal-4355	226	22	collateral	collateral	NOUN
american_scientific_journal-4355	226	23	stasis	stasis	NOUN
american_scientific_journal-4355	226	24	was	be	AUX
american_scientific_journal-4355	226	25	increased	increase	VERB
american_scientific_journal-4355	226	26	with	with	ADP
american_scientific_journal-4355	226	27	the	the	DET
american_scientific_journal-4355	226	28	increasing	increasing	NOUN
american_scientific_journal-4355	226	29	of	of	ADP
american_scientific_journal-4355	226	30	the	the	DET
american_scientific_journal-4355	226	31	degree	degree	NOUN
american_scientific_journal-4355	226	32	of	of	ADP
american_scientific_journal-4355	226	33	renal	renal	ADJ
american_scientific_journal-4355	226	34	interstitial	interstitial	ADJ
american_scientific_journal-4355	226	35	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	226	36	,	,	PUNCT
american_scientific_journal-4355	226	37	as	as	SCONJ
american_scientific_journal-4355	226	38	there	there	PRON
american_scientific_journal-4355	226	39	was	be	VERB
american_scientific_journal-4355	226	40	a	a	DET
american_scientific_journal-4355	226	41	significant	significant	ADJ
american_scientific_journal-4355	226	42	positive	positive	ADJ
american_scientific_journal-4355	226	43	correlation	correlation	NOUN
american_scientific_journal-4355	226	44	between	between	ADP
american_scientific_journal-4355	226	45	kidney	kidney	NOUN
american_scientific_journal-4355	226	46	collateral	collateral	NOUN
american_scientific_journal-4355	226	47	stasis	stasis	NOUN
american_scientific_journal-4355	226	48	and	and	CCONJ
american_scientific_journal-4355	226	49	α	α	NOUN
american_scientific_journal-4355	226	50	-	-	PUNCT
american_scientific_journal-4355	226	51	sma	sma	NOUN
american_scientific_journal-4355	226	52	expression	expression	NOUN
american_scientific_journal-4355	226	53	[	[	X
american_scientific_journal-4355	226	54	50	50	NUM
american_scientific_journal-4355	226	55	]	]	PUNCT
american_scientific_journal-4355	226	56	.	.	PUNCT
american_scientific_journal-4355	227	1	so	so	ADV
american_scientific_journal-4355	227	2	expression	expression	NOUN
american_scientific_journal-4355	227	3	of	of	ADP
american_scientific_journal-4355	227	4	alpha	alpha	NOUN
american_scientific_journal-4355	227	5	-	-	PUNCT
american_scientific_journal-4355	227	6	smooth	smooth	ADJ
american_scientific_journal-4355	227	7	-	-	PUNCT
american_scientific_journal-4355	227	8	muscle	muscle	NOUN
american_scientific_journal-4355	227	9	actin	actin	NOUN
american_scientific_journal-4355	227	10	(	(	PUNCT
american_scientific_journal-4355	227	11	asma	asma	PROPN
american_scientific_journal-4355	227	12	)	)	PUNCT
american_scientific_journal-4355	227	13	has	have	AUX
american_scientific_journal-4355	227	14	suggested	suggest	VERB
american_scientific_journal-4355	227	15	a	a	DET
american_scientific_journal-4355	227	16	new	new	ADJ
american_scientific_journal-4355	227	17	way	way	NOUN
american_scientific_journal-4355	227	18	to	to	PART
american_scientific_journal-4355	227	19	assess	assess	VERB
american_scientific_journal-4355	227	20	clinical	clinical	ADJ
american_scientific_journal-4355	227	21	implications	implication	NOUN
american_scientific_journal-4355	227	22	in	in	ADP
american_scientific_journal-4355	227	23	the	the	DET
american_scientific_journal-4355	227	24	kidney.the	kidney.the	DET
american_scientific_journal-4355	227	25	effect	effect	NOUN
american_scientific_journal-4355	227	26	of	of	ADP
american_scientific_journal-4355	227	27	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	227	28	on	on	ADP
american_scientific_journal-4355	227	29	tgf	tgf	PROPN
american_scientific_journal-4355	227	30	-	-	PUNCT
american_scientific_journal-4355	227	31	βdependent	βdependent	NOUN
american_scientific_journal-4355	227	32	phenotypical	phenotypical	ADJ
american_scientific_journal-4355	227	33	changes	change	NOUN
american_scientific_journal-4355	227	34	in	in	ADP
american_scientific_journal-4355	227	35	human	human	ADJ
american_scientific_journal-4355	227	36	immortalized	immortalize	VERB
american_scientific_journal-4355	227	37	hk2	hk2	PROPN
american_scientific_journal-4355	227	38	has	have	AUX
american_scientific_journal-4355	227	39	been	be	AUX
american_scientific_journal-4355	227	40	examined	examine	VERB
american_scientific_journal-4355	227	41	(	(	PUNCT
american_scientific_journal-4355	227	42	figure	figure	NOUN
american_scientific_journal-4355	227	43	17	17	NUM
american_scientific_journal-4355	227	44	)	)	PUNCT
american_scientific_journal-4355	227	45	.	.	PUNCT
american_scientific_journal-4355	228	1	the	the	DET
american_scientific_journal-4355	228	2	effect	effect	NOUN
american_scientific_journal-4355	228	3	of	of	ADP
american_scientific_journal-4355	228	4	knock	knock	NOUN
american_scientific_journal-4355	228	5	down	down	ADP
american_scientific_journal-4355	228	6	of	of	ADP
american_scientific_journal-4355	228	7	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	228	8	on	on	ADP
american_scientific_journal-4355	228	9	e	e	NOUN
american_scientific_journal-4355	228	10	-	-	NOUN
american_scientific_journal-4355	228	11	cadherin	cadherin	NOUN
american_scientific_journal-4355	228	12	and	and	CCONJ
american_scientific_journal-4355	228	13	alpha	alpha	NOUN
american_scientific_journal-4355	228	14	-	-	PUNCT
american_scientific_journal-4355	228	15	smooth	smooth	ADJ
american_scientific_journal-4355	228	16	-	-	PUNCT
american_scientific_journal-4355	228	17	muscle	muscle	NOUN
american_scientific_journal-4355	228	18	actin	actin	NOUN
american_scientific_journal-4355	228	19	has	have	AUX
american_scientific_journal-4355	228	20	been	be	AUX
american_scientific_journal-4355	228	21	used	use	VERB
american_scientific_journal-4355	228	22	to	to	PART
american_scientific_journal-4355	228	23	investigate	investigate	VERB
american_scientific_journal-4355	228	24	whether	whether	SCONJ
american_scientific_journal-4355	228	25	the	the	DET
american_scientific_journal-4355	228	26	effect	effect	NOUN
american_scientific_journal-4355	228	27	of	of	ADP
american_scientific_journal-4355	228	28	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	228	29	on	on	ADP
american_scientific_journal-4355	228	30	tgf	tgf	PROPN
american_scientific_journal-4355	228	31	-	-	PUNCT
american_scientific_journal-4355	228	32	β	β	PROPN
american_scientific_journal-4355	228	33	induced	induced	ADJ
american_scientific_journal-4355	228	34	signalling	signal	VERB
american_scientific_journal-4355	228	35	resulted	result	VERB
american_scientific_journal-4355	228	36	in	in	ADP
american_scientific_journal-4355	228	37	changes	change	NOUN
american_scientific_journal-4355	228	38	in	in	ADP
american_scientific_journal-4355	228	39	markers	marker	NOUN
american_scientific_journal-4355	228	40	of	of	ADP
american_scientific_journal-4355	228	41	emt	emt	PROPN
american_scientific_journal-4355	228	42	.	.	PUNCT
american_scientific_journal-4355	229	1	figure	figure	NOUN
american_scientific_journal-4355	229	2	17	17	NUM
american_scientific_journal-4355	229	3	:	:	PUNCT
american_scientific_journal-4355	229	4	demonstration	demonstration	NOUN
american_scientific_journal-4355	229	5	of	of	ADP
american_scientific_journal-4355	229	6	the	the	DET
american_scientific_journal-4355	229	7	hk2	hk2	NOUN
american_scientific_journal-4355	229	8	cell	cell	NOUN
american_scientific_journal-4355	229	9	functions	function	NOUN
american_scientific_journal-4355	229	10	in	in	ADP
american_scientific_journal-4355	229	11	terms	term	NOUN
american_scientific_journal-4355	229	12	of	of	ADP
american_scientific_journal-4355	229	13	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	229	14	expression	expression	NOUN
american_scientific_journal-4355	229	15	after	after	ADP
american_scientific_journal-4355	229	16	being	be	AUX
american_scientific_journal-4355	229	17	knocked	knock	VERB
american_scientific_journal-4355	229	18	-	-	PUNCT
american_scientific_journal-4355	229	19	down	down	ADP
american_scientific_journal-4355	229	20	then	then	ADV
american_scientific_journal-4355	229	21	stimulated	stimulate	VERB
american_scientific_journal-4355	229	22	by	by	ADP
american_scientific_journal-4355	229	23	tgf	tgf	PROPN
american_scientific_journal-4355	229	24	-	-	PUNCT
american_scientific_journal-4355	229	25	β	β	NOUN
american_scientific_journal-4355	229	26	:	:	PUNCT
american_scientific_journal-4355	229	27	this	this	DET
american_scientific_journal-4355	229	28	q	q	ADJ
american_scientific_journal-4355	229	29	-	-	ADJ
american_scientific_journal-4355	229	30	pcr	pcr	ADJ
american_scientific_journal-4355	229	31	bar	bar	NOUN
american_scientific_journal-4355	229	32	graph	graph	NOUN
american_scientific_journal-4355	229	33	illustrates	illustrate	VERB
american_scientific_journal-4355	229	34	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	229	35	expression	expression	NOUN
american_scientific_journal-4355	229	36	after	after	SCONJ
american_scientific_journal-4355	229	37	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	229	38	knock	knock	VERB
american_scientific_journal-4355	229	39	-	-	PUNCT
american_scientific_journal-4355	229	40	down	down	NOUN
american_scientific_journal-4355	229	41	then	then	ADV
american_scientific_journal-4355	229	42	tgf	tgf	PROPN
american_scientific_journal-4355	229	43	-	-	PUNCT
american_scientific_journal-4355	229	44	β	β	X
american_scientific_journal-4355	229	45	stimulation	stimulation	NOUN
american_scientific_journal-4355	229	46	at	at	ADP
american_scientific_journal-4355	229	47	different	different	ADJ
american_scientific_journal-4355	229	48	time	time	NOUN
american_scientific_journal-4355	229	49	points	point	NOUN
american_scientific_journal-4355	229	50	,	,	PUNCT
american_scientific_journal-4355	229	51	every	every	DET
american_scientific_journal-4355	229	52	sample	sample	NOUN
american_scientific_journal-4355	229	53	compared	compare	VERB
american_scientific_journal-4355	229	54	to	to	ADP
american_scientific_journal-4355	229	55	the	the	DET
american_scientific_journal-4355	229	56	scramble	scramble	NOUN
american_scientific_journal-4355	229	57	.	.	PUNCT
american_scientific_journal-4355	230	1	2.15	2.15	NUM
american_scientific_journal-4355	230	2	.	.	PUNCT
american_scientific_journal-4355	230	3	demonstration	demonstration	NOUN
american_scientific_journal-4355	230	4	of	of	ADP
american_scientific_journal-4355	230	5	e	e	NOUN
american_scientific_journal-4355	230	6	-	-	NOUN
american_scientific_journal-4355	230	7	cadherin	cadherin	NOUN
american_scientific_journal-4355	230	8	expression	expression	NOUN
american_scientific_journal-4355	230	9	by	by	ADP
american_scientific_journal-4355	230	10	hk2	hk2	PROPN
american_scientific_journal-4355	230	11	cells	cell	NOUN
american_scientific_journal-4355	230	12	after	after	ADP
american_scientific_journal-4355	230	13	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	230	14	knock	knock	VERB
american_scientific_journal-4355	230	15	-	-	PUNCT
american_scientific_journal-4355	230	16	down	down	NOUN
american_scientific_journal-4355	230	17	and	and	CCONJ
american_scientific_journal-4355	230	18	tgf	tgf	PROPN
american_scientific_journal-4355	230	19	-	-	PUNCT
american_scientific_journal-4355	230	20	β	β	PROPN
american_scientific_journal-4355	230	21	stimulation	stimulation	NOUN
american_scientific_journal-4355	230	22	e	e	NOUN
american_scientific_journal-4355	230	23	-	-	NOUN
american_scientific_journal-4355	230	24	cadherin	cadherin	NOUN
american_scientific_journal-4355	230	25	expression	expression	NOUN
american_scientific_journal-4355	230	26	as	as	ADP
american_scientific_journal-4355	230	27	an	an	DET
american_scientific_journal-4355	230	28	element	element	NOUN
american_scientific_journal-4355	230	29	of	of	ADP
american_scientific_journal-4355	230	30	emt	emt	PROPN
american_scientific_journal-4355	230	31	in	in	ADP
american_scientific_journal-4355	230	32	hk2	hk2	PROPN
american_scientific_journal-4355	230	33	cells	cell	NOUN
american_scientific_journal-4355	230	34	was	be	AUX
american_scientific_journal-4355	230	35	investigated	investigate	VERB
american_scientific_journal-4355	230	36	after	after	ADP
american_scientific_journal-4355	230	37	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	230	38	knock	knock	VERB
american_scientific_journal-4355	230	39	-	-	PUNCT
american_scientific_journal-4355	230	40	down	down	NOUN
american_scientific_journal-4355	230	41	in	in	ADP
american_scientific_journal-4355	230	42	the	the	DET
american_scientific_journal-4355	230	43	presence	presence	NOUN
american_scientific_journal-4355	230	44	of	of	ADP
american_scientific_journal-4355	230	45	tgf	tgf	PROPN
american_scientific_journal-4355	230	46	-	-	PUNCT
american_scientific_journal-4355	230	47	β	β	PROPN
american_scientific_journal-4355	230	48	stimulation	stimulation	NOUN
american_scientific_journal-4355	230	49	to	to	PART
american_scientific_journal-4355	230	50	examine	examine	VERB
american_scientific_journal-4355	230	51	whether	whether	SCONJ
american_scientific_journal-4355	230	52	there	there	PRON
american_scientific_journal-4355	230	53	was	be	VERB
american_scientific_journal-4355	230	54	an	an	DET
american_scientific_journal-4355	230	55	association	association	NOUN
american_scientific_journal-4355	230	56	of	of	ADP
american_scientific_journal-4355	230	57	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	230	58	with	with	ADP
american_scientific_journal-4355	230	59	emt	emt	PROPN
american_scientific_journal-4355	230	60	.	.	PUNCT
american_scientific_journal-4355	231	1	the	the	DET
american_scientific_journal-4355	231	2	result	result	NOUN
american_scientific_journal-4355	231	3	was	be	AUX
american_scientific_journal-4355	231	4	that	that	SCONJ
american_scientific_journal-4355	231	5	,	,	PUNCT
american_scientific_journal-4355	231	6	e	e	X
american_scientific_journal-4355	231	7	-	-	NOUN
american_scientific_journal-4355	231	8	cadherin	cadherin	NOUN
american_scientific_journal-4355	231	9	was	be	AUX
american_scientific_journal-4355	231	10	down	down	ADV
american_scientific_journal-4355	231	11	regulated	regulate	VERB
american_scientific_journal-4355	231	12	when	when	SCONJ
american_scientific_journal-4355	231	13	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	231	14	down	down	ADP
american_scientific_journal-4355	231	15	regulated	regulate	VERB
american_scientific_journal-4355	231	16	or	or	CCONJ
american_scientific_journal-4355	231	17	lost	lose	VERB
american_scientific_journal-4355	231	18	(	(	PUNCT
american_scientific_journal-4355	231	19	figure	figure	NOUN
american_scientific_journal-4355	231	20	18	18	NUM
american_scientific_journal-4355	231	21	)	)	PUNCT
american_scientific_journal-4355	231	22	which	which	PRON
american_scientific_journal-4355	231	23	suggested	suggest	VERB
american_scientific_journal-4355	231	24	that	that	SCONJ
american_scientific_journal-4355	231	25	there	there	PRON
american_scientific_journal-4355	231	26	was	be	VERB
american_scientific_journal-4355	231	27	an	an	DET
american_scientific_journal-4355	231	28	element	element	NOUN
american_scientific_journal-4355	231	29	of	of	ADP
american_scientific_journal-4355	231	30	emt	emt	PROPN
american_scientific_journal-4355	231	31	in	in	ADP
american_scientific_journal-4355	231	32	most	most	ADJ
american_scientific_journal-4355	231	33	of	of	ADP
american_scientific_journal-4355	231	34	the	the	DET
american_scientific_journal-4355	231	35	time	time	NOUN
american_scientific_journal-4355	231	36	points	point	NOUN
american_scientific_journal-4355	231	37	.	.	PUNCT
american_scientific_journal-4355	232	1	figure	figure	VERB
american_scientific_journal-4355	232	2	18	18	NUM
american_scientific_journal-4355	232	3	:	:	PUNCT
american_scientific_journal-4355	232	4	q	q	ADJ
american_scientific_journal-4355	232	5	-	-	PUNCT
american_scientific_journal-4355	232	6	pcr	pcr	ADJ
american_scientific_journal-4355	232	7	illustrates	illustrate	VERB
american_scientific_journal-4355	232	8	e	e	NOUN
american_scientific_journal-4355	232	9	-	-	NOUN
american_scientific_journal-4355	232	10	cadherin	cadherin	NOUN
american_scientific_journal-4355	232	11	expression	expression	NOUN
american_scientific_journal-4355	232	12	after	after	SCONJ
american_scientific_journal-4355	232	13	bg	bg	PROPN
american_scientific_journal-4355	232	14	knock	knock	VERB
american_scientific_journal-4355	232	15	-	-	PUNCT
american_scientific_journal-4355	232	16	down	down	NOUN
american_scientific_journal-4355	232	17	and	and	CCONJ
american_scientific_journal-4355	232	18	tgf	tgf	PROPN
american_scientific_journal-4355	232	19	-	-	PUNCT
american_scientific_journal-4355	232	20	β	β	PROPN
american_scientific_journal-4355	232	21	stimulation	stimulation	NOUN
american_scientific_journal-4355	232	22	q	q	ADJ
american_scientific_journal-4355	232	23	-	-	PUNCT
american_scientific_journal-4355	232	24	pcr	pcr	NOUN
american_scientific_journal-4355	232	25	illustrates	illustrate	VERB
american_scientific_journal-4355	232	26	the	the	DET
american_scientific_journal-4355	232	27	e	e	NOUN
american_scientific_journal-4355	232	28	-	-	NOUN
american_scientific_journal-4355	232	29	cadherin	cadherin	NOUN
american_scientific_journal-4355	232	30	expression	expression	NOUN
american_scientific_journal-4355	232	31	after	after	ADP
american_scientific_journal-4355	232	32	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	232	33	knock	knock	VERB
american_scientific_journal-4355	232	34	-	-	PUNCT
american_scientific_journal-4355	232	35	down	down	NOUN
american_scientific_journal-4355	232	36	and	and	CCONJ
american_scientific_journal-4355	232	37	tgf	tgf	PROPN
american_scientific_journal-4355	232	38	-	-	PUNCT
american_scientific_journal-4355	232	39	β	β	PROPN
american_scientific_journal-4355	232	40	stimulation	stimulation	NOUN
american_scientific_journal-4355	232	41	at	at	ADP
american_scientific_journal-4355	232	42	different	different	ADJ
american_scientific_journal-4355	232	43	time	time	NOUN
american_scientific_journal-4355	232	44	points	point	NOUN
american_scientific_journal-4355	232	45	,	,	PUNCT
american_scientific_journal-4355	232	46	every	every	DET
american_scientific_journal-4355	232	47	sample	sample	NOUN
american_scientific_journal-4355	232	48	compared	compare	VERB
american_scientific_journal-4355	232	49	to	to	ADP
american_scientific_journal-4355	232	50	the	the	DET
american_scientific_journal-4355	232	51	scramble	scramble	ADJ
american_scientific_journal-4355	232	52	one	one	NUM
american_scientific_journal-4355	232	53	2.16	2.16	NUM
american_scientific_journal-4355	232	54	.	.	PUNCT
american_scientific_journal-4355	233	1	demonstration	demonstration	NOUN
american_scientific_journal-4355	233	2	of	of	ADP
american_scientific_journal-4355	233	3	α	α	NOUN
american_scientific_journal-4355	233	4	-	-	PUNCT
american_scientific_journal-4355	233	5	sma	sma	NOUN
american_scientific_journal-4355	233	6	expression	expression	NOUN
american_scientific_journal-4355	233	7	of	of	ADP
american_scientific_journal-4355	233	8	hk2	hk2	NOUN
american_scientific_journal-4355	233	9	cells	cell	NOUN
american_scientific_journal-4355	233	10	after	after	ADP
american_scientific_journal-4355	233	11	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	233	12	knock	knock	VERB
american_scientific_journal-4355	233	13	-	-	PUNCT
american_scientific_journal-4355	233	14	down	down	NOUN
american_scientific_journal-4355	233	15	and	and	CCONJ
american_scientific_journal-4355	233	16	tgf	tgf	PROPN
american_scientific_journal-4355	233	17	-	-	PUNCT
american_scientific_journal-4355	233	18	β	β	PROPN
american_scientific_journal-4355	233	19	stimulation	stimulation	NOUN
american_scientific_journal-4355	233	20	alpha	alpha	NOUN
american_scientific_journal-4355	233	21	smooth	smooth	ADJ
american_scientific_journal-4355	233	22	muscle	muscle	NOUN
american_scientific_journal-4355	233	23	actin	actin	NOUN
american_scientific_journal-4355	233	24	expression	expression	NOUN
american_scientific_journal-4355	233	25	as	as	ADP
american_scientific_journal-4355	233	26	an	an	DET
american_scientific_journal-4355	233	27	element	element	NOUN
american_scientific_journal-4355	233	28	of	of	ADP
american_scientific_journal-4355	233	29	emt	emt	PROPN
american_scientific_journal-4355	233	30	in	in	ADP
american_scientific_journal-4355	233	31	hk2	hk2	PROPN
american_scientific_journal-4355	233	32	cells	cell	NOUN
american_scientific_journal-4355	233	33	was	be	AUX
american_scientific_journal-4355	233	34	investigated	investigate	VERB
american_scientific_journal-4355	233	35	after	after	ADP
american_scientific_journal-4355	233	36	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	233	37	knock	knock	VERB
american_scientific_journal-4355	233	38	-	-	PUNCT
american_scientific_journal-4355	233	39	down	down	NOUN
american_scientific_journal-4355	233	40	in	in	ADP
american_scientific_journal-4355	233	41	the	the	DET
american_scientific_journal-4355	233	42	presence	presence	NOUN
american_scientific_journal-4355	233	43	of	of	ADP
american_scientific_journal-4355	233	44	tgf	tgf	PROPN
american_scientific_journal-4355	233	45	-	-	PUNCT
american_scientific_journal-4355	233	46	β	β	PROPN
american_scientific_journal-4355	233	47	stimulation	stimulation	NOUN
american_scientific_journal-4355	233	48	to	to	PART
american_scientific_journal-4355	233	49	examine	examine	VERB
american_scientific_journal-4355	233	50	whether	whether	SCONJ
american_scientific_journal-4355	233	51	there	there	PRON
american_scientific_journal-4355	233	52	was	be	VERB
american_scientific_journal-4355	233	53	an	an	DET
american_scientific_journal-4355	233	54	association	association	NOUN
american_scientific_journal-4355	233	55	of	of	ADP
american_scientific_journal-4355	233	56	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	233	57	with	with	ADP
american_scientific_journal-4355	233	58	emt	emt	PROPN
american_scientific_journal-4355	233	59	.	.	PUNCT
american_scientific_journal-4355	234	1	this	this	PRON
american_scientific_journal-4355	234	2	is	be	AUX
american_scientific_journal-4355	234	3	done	do	VERB
american_scientific_journal-4355	234	4	by	by	ADP
american_scientific_journal-4355	234	5	real	real	ADJ
american_scientific_journal-4355	234	6	-	-	PUNCT
american_scientific_journal-4355	234	7	time	time	NOUN
american_scientific_journal-4355	234	8	quantitative	quantitative	ADJ
american_scientific_journal-4355	234	9	pcr(figure	pcr(figure	NOUN
american_scientific_journal-4355	234	10	19	19	NUM
american_scientific_journal-4355	234	11	)	)	PUNCT
american_scientific_journal-4355	234	12	.	.	PUNCT
american_scientific_journal-4355	235	1	the	the	DET
american_scientific_journal-4355	235	2	result	result	NOUN
american_scientific_journal-4355	235	3	of	of	ADP
american_scientific_journal-4355	235	4	α	α	NOUN
american_scientific_journal-4355	235	5	-	-	PUNCT
american_scientific_journal-4355	235	6	sma	sma	NOUN
american_scientific_journal-4355	235	7	was	be	AUX
american_scientific_journal-4355	235	8	mildly	mildly	ADV
american_scientific_journal-4355	235	9	up	up	ADV
american_scientific_journal-4355	235	10	-	-	PUNCT
american_scientific_journal-4355	235	11	regulated	regulate	VERB
american_scientific_journal-4355	235	12	which	which	PRON
american_scientific_journal-4355	235	13	suggested	suggest	VERB
american_scientific_journal-4355	235	14	that	that	SCONJ
american_scientific_journal-4355	235	15	there	there	PRON
american_scientific_journal-4355	235	16	was	be	VERB
american_scientific_journal-4355	235	17	an	an	DET
american_scientific_journal-4355	235	18	element	element	NOUN
american_scientific_journal-4355	235	19	of	of	ADP
american_scientific_journal-4355	235	20	emt	emt	PROPN
american_scientific_journal-4355	235	21	when	when	SCONJ
american_scientific_journal-4355	235	22	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	235	23	was	be	AUX
american_scientific_journal-4355	235	24	lost	lose	VERB
american_scientific_journal-4355	235	25	.	.	PUNCT
american_scientific_journal-4355	236	1	figure	figure	VERB
american_scientific_journal-4355	236	2	19	19	NUM
american_scientific_journal-4355	236	3	:	:	PUNCT
american_scientific_journal-4355	236	4	q	q	ADJ
american_scientific_journal-4355	236	5	-	-	PUNCT
american_scientific_journal-4355	236	6	pcr	pcr	NOUN
american_scientific_journal-4355	236	7	illustrates	illustrate	VERB
american_scientific_journal-4355	236	8	α	α	NOUN
american_scientific_journal-4355	236	9	-	-	PUNCT
american_scientific_journal-4355	236	10	sma	sma	NOUN
american_scientific_journal-4355	236	11	expression	expression	NOUN
american_scientific_journal-4355	236	12	after	after	SCONJ
american_scientific_journal-4355	236	13	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	236	14	knock	knock	VERB
american_scientific_journal-4355	236	15	-	-	PUNCT
american_scientific_journal-4355	236	16	down	down	NOUN
american_scientific_journal-4355	236	17	and	and	CCONJ
american_scientific_journal-4355	236	18	tgf	tgf	PROPN
american_scientific_journal-4355	236	19	-	-	PUNCT
american_scientific_journal-4355	236	20	β	β	PROPN
american_scientific_journal-4355	236	21	stimulation	stimulation	NOUN
american_scientific_journal-4355	236	22	2.16	2.16	NUM
american_scientific_journal-4355	236	23	.	.	PUNCT
american_scientific_journal-4355	237	1	relationship	relationship	NOUN
american_scientific_journal-4355	237	2	of	of	ADP
american_scientific_journal-4355	237	3	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	237	4	to	to	ADP
american_scientific_journal-4355	237	5	pai-1	pai-1	NUM
american_scientific_journal-4355	237	6	(	(	PUNCT
american_scientific_journal-4355	237	7	plasminogen	plasminogen	NOUN
american_scientific_journal-4355	237	8	activator	activator	NOUN
american_scientific_journal-4355	237	9	inhibitor-1	inhibitor-1	NUM
american_scientific_journal-4355	237	10	)	)	PUNCT
american_scientific_journal-4355	237	11	the	the	DET
american_scientific_journal-4355	237	12	purpose	purpose	NOUN
american_scientific_journal-4355	237	13	of	of	ADP
american_scientific_journal-4355	237	14	the	the	DET
american_scientific_journal-4355	237	15	experiment	experiment	NOUN
american_scientific_journal-4355	237	16	was	be	AUX
american_scientific_journal-4355	237	17	to	to	PART
american_scientific_journal-4355	237	18	determine	determine	VERB
american_scientific_journal-4355	237	19	whether	whether	SCONJ
american_scientific_journal-4355	237	20	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	237	21	knock	knock	VERB
american_scientific_journal-4355	237	22	-	-	PUNCT
american_scientific_journal-4355	237	23	down	down	ADP
american_scientific_journal-4355	237	24	induced	induced	ADJ
american_scientific_journal-4355	237	25	tgf	tgf	PROPN
american_scientific_journal-4355	237	26	-	-	PUNCT
american_scientific_journal-4355	237	27	β	β	X
american_scientific_journal-4355	237	28	down	down	ADP
american_scientific_journal-4355	237	29	regulation	regulation	NOUN
american_scientific_journal-4355	237	30	as	as	ADP
american_scientific_journal-4355	237	31	a	a	DET
american_scientific_journal-4355	237	32	direct	direct	ADJ
american_scientific_journal-4355	237	33	action	action	NOUN
american_scientific_journal-4355	237	34	or	or	CCONJ
american_scientific_journal-4355	237	35	through	through	ADP
american_scientific_journal-4355	237	36	pai-1	pai-1	NUM
american_scientific_journal-4355	237	37	which	which	PRON
american_scientific_journal-4355	237	38	is	be	AUX
american_scientific_journal-4355	237	39	the	the	DET
american_scientific_journal-4355	237	40	mean	mean	PROPN
american_scientific_journal-4355	237	41	tgf	tgf	PROPN
american_scientific_journal-4355	237	42	-	-	PUNCT
american_scientific_journal-4355	237	43	β	β	NOUN
american_scientific_journal-4355	237	44	inducer	inducer	NOUN
american_scientific_journal-4355	237	45	.	.	PUNCT
american_scientific_journal-4355	238	1	in	in	ADP
american_scientific_journal-4355	238	2	this	this	DET
american_scientific_journal-4355	238	3	experiment	experiment	NOUN
american_scientific_journal-4355	238	4	,	,	PUNCT
american_scientific_journal-4355	238	5	when	when	SCONJ
american_scientific_journal-4355	238	6	tgf	tgf	PROPN
american_scientific_journal-4355	238	7	-	-	PUNCT
american_scientific_journal-4355	238	8	β	β	PROPN
american_scientific_journal-4355	238	9	applied	apply	VERB
american_scientific_journal-4355	238	10	,	,	PUNCT
american_scientific_journal-4355	238	11	pai-1	pai-1	NUM
american_scientific_journal-4355	238	12	expression	expression	NOUN
american_scientific_journal-4355	238	13	increased	increase	VERB
american_scientific_journal-4355	238	14	that	that	PRON
american_scientific_journal-4355	238	15	means	mean	VERB
american_scientific_journal-4355	238	16	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	238	17	knock	knock	VERB
american_scientific_journal-4355	238	18	-	-	PUNCT
american_scientific_journal-4355	238	19	down	down	NOUN
american_scientific_journal-4355	238	20	does	do	AUX
american_scientific_journal-4355	238	21	not	not	PART
american_scientific_journal-4355	238	22	depends	depend	VERB
american_scientific_journal-4355	238	23	on	on	ADP
american_scientific_journal-4355	238	24	pai-1	pai-1	NUM
american_scientific_journal-4355	238	25	action.type-1	action.type-1	NOUN
american_scientific_journal-4355	238	26	inhibitor	inhibitor	NOUN
american_scientific_journal-4355	238	27	of	of	ADP
american_scientific_journal-4355	238	28	plasminogen	plasminogen	NOUN
american_scientific_journal-4355	238	29	activator	activator	NOUN
american_scientific_journal-4355	238	30	(	(	PUNCT
american_scientific_journal-4355	238	31	pai-1	pai-1	NUM
american_scientific_journal-4355	238	32	)	)	PUNCT
american_scientific_journal-4355	238	33	is	be	AUX
american_scientific_journal-4355	238	34	an	an	DET
american_scientific_journal-4355	238	35	important	important	ADJ
american_scientific_journal-4355	238	36	physiological	physiological	ADJ
american_scientific_journal-4355	238	37	regulator	regulator	NOUN
american_scientific_journal-4355	238	38	of	of	ADP
american_scientific_journal-4355	238	39	extracellular	extracellular	ADJ
american_scientific_journal-4355	238	40	matrix	matrix	NOUN
american_scientific_journal-4355	238	41	(	(	PUNCT
american_scientific_journal-4355	238	42	ecm	ecm	NOUN
american_scientific_journal-4355	238	43	)	)	PUNCT
american_scientific_journal-4355	238	44	homeostasis	homeostasis	NOUN
american_scientific_journal-4355	238	45	and	and	CCONJ
american_scientific_journal-4355	238	46	cell	cell	NOUN
american_scientific_journal-4355	238	47	motility	motility	NOUN
american_scientific_journal-4355	238	48	.	.	PUNCT
american_scientific_journal-4355	239	1	tgf	tgf	PROPN
american_scientific_journal-4355	239	2	-	-	PUNCT
american_scientific_journal-4355	239	3	β1	β1	PROPN
american_scientific_journal-4355	239	4	,	,	PUNCT
american_scientific_journal-4355	239	5	in	in	ADP
american_scientific_journal-4355	239	6	particular	particular	ADJ
american_scientific_journal-4355	239	7	,	,	PUNCT
american_scientific_journal-4355	239	8	is	be	AUX
american_scientific_journal-4355	239	9	a	a	DET
american_scientific_journal-4355	239	10	powerful	powerful	ADJ
american_scientific_journal-4355	239	11	inducer	inducer	NOUN
american_scientific_journal-4355	239	12	of	of	ADP
american_scientific_journal-4355	239	13	matrix	matrix	NOUN
american_scientific_journal-4355	239	14	deposition	deposition	NOUN
american_scientific_journal-4355	239	15	/	/	SYM
american_scientific_journal-4355	239	16	turnover	turnover	NOUN
american_scientific_journal-4355	239	17	,	,	PUNCT
american_scientific_journal-4355	239	18	cell	cell	NOUN
american_scientific_journal-4355	239	19	locomotion	locomotion	NOUN
american_scientific_journal-4355	239	20	and	and	CCONJ
american_scientific_journal-4355	239	21	pai-1	pai-1	ADJ
american_scientific_journal-4355	239	22	expression	expression	NOUN
american_scientific_journal-4355	239	23	.	.	PUNCT
american_scientific_journal-4355	240	1	plasminogen	plasminogen	NOUN
american_scientific_journal-4355	240	2	activator	activator	NOUN
american_scientific_journal-4355	240	3	inhibitor-1	inhibitor-1	NUM
american_scientific_journal-4355	240	4	is	be	AUX
american_scientific_journal-4355	240	5	the	the	DET
american_scientific_journal-4355	240	6	main	main	ADJ
american_scientific_journal-4355	240	7	inhibitor	inhibitor	NOUN
american_scientific_journal-4355	240	8	of	of	ADP
american_scientific_journal-4355	240	9	tissue	tissue	NOUN
american_scientific_journal-4355	240	10	plasminogen	plasminogen	NOUN
american_scientific_journal-4355	240	11	activator	activator	NOUN
american_scientific_journal-4355	240	12	(	(	PUNCT
american_scientific_journal-4355	240	13	tpa	tpa	NOUN
american_scientific_journal-4355	240	14	)	)	PUNCT
american_scientific_journal-4355	240	15	and	and	CCONJ
american_scientific_journal-4355	240	16	urokinase	urokinase	NOUN
american_scientific_journal-4355	240	17	(	(	PUNCT
american_scientific_journal-4355	240	18	upa	upa	NOUN
american_scientific_journal-4355	240	19	)	)	PUNCT
american_scientific_journal-4355	240	20	,	,	PUNCT
american_scientific_journal-4355	240	21	the	the	DET
american_scientific_journal-4355	240	22	activators	activator	NOUN
american_scientific_journal-4355	240	23	of	of	ADP
american_scientific_journal-4355	240	24	plasminogen	plasminogen	NOUN
american_scientific_journal-4355	240	25	and	and	CCONJ
american_scientific_journal-4355	240	26	hence	hence	ADV
american_scientific_journal-4355	240	27	fibrinolysis	fibrinolysis	VERB
american_scientific_journal-4355	240	28	.	.	PUNCT
american_scientific_journal-4355	241	1	high	high	ADJ
american_scientific_journal-4355	241	2	levels	level	NOUN
american_scientific_journal-4355	241	3	of	of	ADP
american_scientific_journal-4355	241	4	pai-1	pai-1	PRON
american_scientific_journal-4355	241	5	are	be	AUX
american_scientific_journal-4355	241	6	found	find	VERB
american_scientific_journal-4355	241	7	in	in	ADP
american_scientific_journal-4355	241	8	severe	severe	ADJ
american_scientific_journal-4355	241	9	sepsis	sepsis	NOUN
american_scientific_journal-4355	241	10	while	while	SCONJ
american_scientific_journal-4355	241	11	low	low	ADJ
american_scientific_journal-4355	241	12	levels	level	NOUN
american_scientific_journal-4355	241	13	or	or	CCONJ
american_scientific_journal-4355	241	14	deficiency	deficiency	NOUN
american_scientific_journal-4355	241	15	are	be	AUX
american_scientific_journal-4355	241	16	found	find	VERB
american_scientific_journal-4355	241	17	in	in	ADP
american_scientific_journal-4355	241	18	bleeding	bleeding	NOUN
american_scientific_journal-4355	241	19	.	.	PUNCT
american_scientific_journal-4355	242	1	thus	thus	ADV
american_scientific_journal-4355	242	2	plays	play	VERB
american_scientific_journal-4355	242	3	a	a	DET
american_scientific_journal-4355	242	4	role	role	NOUN
american_scientific_journal-4355	242	5	in	in	ADP
american_scientific_journal-4355	242	6	inflammatory	inflammatory	ADJ
american_scientific_journal-4355	242	7	lung	lung	NOUN
american_scientific_journal-4355	242	8	disease	disease	NOUN
american_scientific_journal-4355	242	9	and	and	CCONJ
american_scientific_journal-4355	242	10	malignancy	malignancy	NOUN
american_scientific_journal-4355	242	11	.	.	PUNCT
american_scientific_journal-4355	243	1	it	it	PRON
american_scientific_journal-4355	243	2	has	have	VERB
american_scientific_journal-4355	243	3	an	an	DET
american_scientific_journal-4355	243	4	important	important	ADJ
american_scientific_journal-4355	243	5	role	role	NOUN
american_scientific_journal-4355	243	6	in	in	ADP
american_scientific_journal-4355	243	7	renal	renal	ADJ
american_scientific_journal-4355	243	8	disease	disease	NOUN
american_scientific_journal-4355	243	9	where	where	SCONJ
american_scientific_journal-4355	243	10	high	high	ADJ
american_scientific_journal-4355	243	11	levels	level	NOUN
american_scientific_journal-4355	243	12	of	of	ADP
american_scientific_journal-4355	243	13	pai-1	pai-1	PRON
american_scientific_journal-4355	243	14	are	be	AUX
american_scientific_journal-4355	243	15	found	find	VERB
american_scientific_journal-4355	243	16	in	in	ADP
american_scientific_journal-4355	243	17	nephritic	nephritic	ADJ
american_scientific_journal-4355	243	18	and	and	CCONJ
american_scientific_journal-4355	243	19	haemolytic	haemolytic	ADJ
american_scientific_journal-4355	243	20	uremic	uremic	ADJ
american_scientific_journal-4355	243	21	syndrome	syndrome	NOUN
american_scientific_journal-4355	243	22	.	.	PUNCT
american_scientific_journal-4355	244	1	the	the	DET
american_scientific_journal-4355	244	2	following	follow	VERB
american_scientific_journal-4355	244	3	experiment	experiment	NOUN
american_scientific_journal-4355	244	4	,	,	PUNCT
american_scientific_journal-4355	244	5	tries	try	VERB
american_scientific_journal-4355	244	6	to	to	PART
american_scientific_journal-4355	244	7	determine	determine	VERB
american_scientific_journal-4355	244	8	the	the	DET
american_scientific_journal-4355	244	9	relationship	relationship	NOUN
american_scientific_journal-4355	244	10	between	between	ADP
american_scientific_journal-4355	244	11	pai-1	pai-1	NUM
american_scientific_journal-4355	244	12	and	and	CCONJ
american_scientific_journal-4355	244	13	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	244	14	,	,	PUNCT
american_scientific_journal-4355	244	15	and	and	CCONJ
american_scientific_journal-4355	244	16	as	as	SCONJ
american_scientific_journal-4355	244	17	tgf	tgf	PROPN
american_scientific_journal-4355	244	18	-	-	PUNCT
american_scientific_journal-4355	244	19	β	β	PROPN
american_scientific_journal-4355	244	20	induces	induce	VERB
american_scientific_journal-4355	244	21	pai-1	pai-1	NUM
american_scientific_journal-4355	244	22	,	,	PUNCT
american_scientific_journal-4355	244	23	(	(	PUNCT
american_scientific_journal-4355	244	24	figure	figure	NOUN
american_scientific_journal-4355	244	25	20	20	NUM
american_scientific_journal-4355	244	26	)	)	PUNCT
american_scientific_journal-4355	244	27	.	.	PUNCT
american_scientific_journal-4355	245	1	starting	start	VERB
american_scientific_journal-4355	245	2	the	the	DET
american_scientific_journal-4355	245	3	experiment	experiment	NOUN
american_scientific_journal-4355	245	4	which	which	PRON
american_scientific_journal-4355	245	5	lasts	last	VERB
american_scientific_journal-4355	245	6	48	48	NUM
american_scientific_journal-4355	245	7	hours	hour	NOUN
american_scientific_journal-4355	245	8	in	in	ADP
american_scientific_journal-4355	245	9	triplicate	triplicate	NOUN
american_scientific_journal-4355	245	10	samples	sample	NOUN
american_scientific_journal-4355	245	11	,	,	PUNCT
american_scientific_journal-4355	245	12	mrna	mrna	PROPN
american_scientific_journal-4355	245	13	was	be	AUX
american_scientific_journal-4355	245	14	isolated	isolate	VERB
american_scientific_journal-4355	245	15	,	,	PUNCT
american_scientific_journal-4355	245	16	reverse	reverse	ADJ
american_scientific_journal-4355	245	17	transcribed	transcribe	VERB
american_scientific_journal-4355	245	18	,	,	PUNCT
american_scientific_journal-4355	245	19	then	then	ADV
american_scientific_journal-4355	245	20	quantified	quantify	VERB
american_scientific_journal-4355	245	21	by	by	ADP
american_scientific_journal-4355	245	22	real	real	ADJ
american_scientific_journal-4355	245	23	-	-	PUNCT
american_scientific_journal-4355	245	24	time	time	NOUN
american_scientific_journal-4355	245	25	quantitative	quantitative	ADJ
american_scientific_journal-4355	245	26	pcr	pcr	NOUN
american_scientific_journal-4355	245	27	.	.	PUNCT
american_scientific_journal-4355	246	1	the	the	DET
american_scientific_journal-4355	246	2	result	result	NOUN
american_scientific_journal-4355	246	3	of	of	ADP
american_scientific_journal-4355	246	4	pai-1	pai-1	NUM
american_scientific_journal-4355	246	5	was	be	AUX
american_scientific_journal-4355	246	6	down	down	ADV
american_scientific_journal-4355	246	7	regulated	regulated	ADJ
american_scientific_journal-4355	246	8	but	but	CCONJ
american_scientific_journal-4355	246	9	when	when	SCONJ
american_scientific_journal-4355	246	10	tgf	tgf	PROPN
american_scientific_journal-4355	246	11	-	-	PUNCT
american_scientific_journal-4355	246	12	β	β	PROPN
american_scientific_journal-4355	246	13	was	be	AUX
american_scientific_journal-4355	246	14	given	give	VERB
american_scientific_journal-4355	246	15	,	,	PUNCT
american_scientific_journal-4355	246	16	pai-1	pai-1	NUM
american_scientific_journal-4355	246	17	expression	expression	NOUN
american_scientific_journal-4355	246	18	was	be	AUX
american_scientific_journal-4355	246	19	increased	increase	VERB
american_scientific_journal-4355	246	20	,	,	PUNCT
american_scientific_journal-4355	246	21	that	that	PRON
american_scientific_journal-4355	246	22	means	mean	VERB
american_scientific_journal-4355	246	23	pai-1	pai-1	NUM
american_scientific_journal-4355	246	24	has	have	VERB
american_scientific_journal-4355	246	25	no	no	DET
american_scientific_journal-4355	246	26	relationship	relationship	NOUN
american_scientific_journal-4355	246	27	with	with	ADP
american_scientific_journal-4355	246	28	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	246	29	when	when	SCONJ
american_scientific_journal-4355	246	30	it	it	PRON
american_scientific_journal-4355	246	31	acts	act	VERB
american_scientific_journal-4355	246	32	on	on	ADP
american_scientific_journal-4355	246	33	tgf	tgf	PROPN
american_scientific_journal-4355	246	34	-	-	PUNCT
american_scientific_journal-4355	246	35	β	β	PROPN
american_scientific_journal-4355	246	36	which	which	PRON
american_scientific_journal-4355	246	37	instead	instead	ADV
american_scientific_journal-4355	246	38	it	it	PRON
american_scientific_journal-4355	246	39	has	have	AUX
american_scientific_journal-4355	246	40	been	be	AUX
american_scientific_journal-4355	246	41	induced	induce	VERB
american_scientific_journal-4355	246	42	leading	lead	VERB
american_scientific_journal-4355	246	43	to	to	ADP
american_scientific_journal-4355	246	44	relatively	relatively	ADV
american_scientific_journal-4355	246	45	increased	increase	VERB
american_scientific_journal-4355	246	46	pai-1	pai-1	PUNCT
american_scientific_journal-4355	246	47	expression	expression	NOUN
american_scientific_journal-4355	246	48	(	(	PUNCT
american_scientific_journal-4355	246	49	figure	figure	NOUN
american_scientific_journal-4355	246	50	20	20	NUM
american_scientific_journal-4355	246	51	)	)	PUNCT
american_scientific_journal-4355	246	52	.	.	PUNCT
american_scientific_journal-4355	247	1	figure	figure	VERB
american_scientific_journal-4355	247	2	20	20	NUM
american_scientific_journal-4355	247	3	:	:	PUNCT
american_scientific_journal-4355	247	4	plasminogen	plasminogen	NOUN
american_scientific_journal-4355	247	5	activator	activator	NOUN
american_scientific_journal-4355	247	6	inhibitor-1	inhibitor-1	NUM
american_scientific_journal-4355	247	7	and	and	CCONJ
american_scientific_journal-4355	247	8	bg	bg	PROPN
american_scientific_journal-4355	247	9	.	.	PROPN
american_scientific_journal-4355	247	10	relationship	relationship	NOUN
american_scientific_journal-4355	247	11	the	the	DET
american_scientific_journal-4355	247	12	above	above	ADJ
american_scientific_journal-4355	247	13	is	be	AUX
american_scientific_journal-4355	247	14	q	q	ADJ
american_scientific_journal-4355	247	15	-	-	ADJ
american_scientific_journal-4355	247	16	pcr	pcr	ADJ
american_scientific_journal-4355	247	17	paragraph	paragraph	NOUN
american_scientific_journal-4355	247	18	of	of	ADP
american_scientific_journal-4355	247	19	pai-1	pai-1	ADJ
american_scientific_journal-4355	247	20	expressions	expression	NOUN
american_scientific_journal-4355	247	21	following	follow	VERB
american_scientific_journal-4355	247	22	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	247	23	knock	knock	VERB
american_scientific_journal-4355	247	24	-	-	PUNCT
american_scientific_journal-4355	247	25	down	down	NOUN
american_scientific_journal-4355	247	26	with	with	ADP
american_scientific_journal-4355	247	27	and	and	CCONJ
american_scientific_journal-4355	247	28	without	without	ADP
american_scientific_journal-4355	247	29	tgf	tgf	PROPN
american_scientific_journal-4355	247	30	-	-	PUNCT
american_scientific_journal-4355	247	31	β	β	PROPN
american_scientific_journal-4355	247	32	stimulation	stimulation	NOUN
american_scientific_journal-4355	247	33	at	at	ADP
american_scientific_journal-4355	247	34	different	different	ADJ
american_scientific_journal-4355	247	35	time	time	NOUN
american_scientific_journal-4355	247	36	points	point	NOUN
american_scientific_journal-4355	247	37	,	,	PUNCT
american_scientific_journal-4355	247	38	every	every	DET
american_scientific_journal-4355	247	39	sample	sample	NOUN
american_scientific_journal-4355	247	40	compared	compare	VERB
american_scientific_journal-4355	247	41	to	to	ADP
american_scientific_journal-4355	247	42	the	the	DET
american_scientific_journal-4355	247	43	scrample	scrample	ADJ
american_scientific_journal-4355	247	44	one	one	NUM
american_scientific_journal-4355	247	45	.	.	PUNCT
american_scientific_journal-4355	248	1	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	248	2	might	might	AUX
american_scientific_journal-4355	248	3	occur	occur	VERB
american_scientific_journal-4355	248	4	in	in	ADP
american_scientific_journal-4355	248	5	a	a	DET
american_scientific_journal-4355	248	6	variety	variety	NOUN
american_scientific_journal-4355	248	7	of	of	ADP
american_scientific_journal-4355	248	8	organs	organ	NOUN
american_scientific_journal-4355	248	9	which	which	PRON
american_scientific_journal-4355	248	10	are	be	AUX
american_scientific_journal-4355	248	11	mainly	mainly	ADV
american_scientific_journal-4355	248	12	composed	compose	VERB
american_scientific_journal-4355	248	13	of	of	ADP
american_scientific_journal-4355	248	14	epithelial	epithelial	ADJ
american_scientific_journal-4355	248	15	cells	cell	NOUN
american_scientific_journal-4355	248	16	,	,	PUNCT
american_scientific_journal-4355	248	17	such	such	ADJ
american_scientific_journal-4355	248	18	as	as	ADP
american_scientific_journal-4355	248	19	kidney	kidney	NOUN
american_scientific_journal-4355	248	20	,	,	PUNCT
american_scientific_journal-4355	248	21	lung	lung	NOUN
american_scientific_journal-4355	248	22	and	and	CCONJ
american_scientific_journal-4355	248	23	the	the	DET
american_scientific_journal-4355	248	24	liver[51	liver[51	ADJ
american_scientific_journal-4355	248	25	]	]	PUNCT
american_scientific_journal-4355	248	26	.	.	PUNCT
american_scientific_journal-4355	249	1	inflammatory	inflammatory	ADJ
american_scientific_journal-4355	249	2	signals	signal	NOUN
american_scientific_journal-4355	249	3	derived	derive	VERB
american_scientific_journal-4355	249	4	from	from	ADP
american_scientific_journal-4355	249	5	proliferating	proliferate	VERB
american_scientific_journal-4355	249	6	interstitial	interstitial	ADJ
american_scientific_journal-4355	249	7	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	249	8	and	and	CCONJ
american_scientific_journal-4355	249	9	inflammatory	inflammatory	ADJ
american_scientific_journal-4355	249	10	cells	cell	NOUN
american_scientific_journal-4355	249	11	lead	lead	VERB
american_scientific_journal-4355	249	12	to	to	ADP
american_scientific_journal-4355	249	13	an	an	DET
american_scientific_journal-4355	249	14	expanded	expand	VERB
american_scientific_journal-4355	249	15	ecm	ecm	NOUN
american_scientific_journal-4355	249	16	and	and	CCONJ
american_scientific_journal-4355	249	17	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	249	18	.	.	PUNCT
american_scientific_journal-4355	250	1	the	the	DET
american_scientific_journal-4355	250	2	analyses	analysis	NOUN
american_scientific_journal-4355	250	3	of	of	ADP
american_scientific_journal-4355	250	4	diseased	diseased	ADJ
american_scientific_journal-4355	250	5	human	human	ADJ
american_scientific_journal-4355	250	6	kidney	kidney	NOUN
american_scientific_journal-4355	250	7	biopsies	biopsy	NOUN
american_scientific_journal-4355	250	8	,	,	PUNCT
american_scientific_journal-4355	250	9	revealed	reveal	VERB
american_scientific_journal-4355	250	10	the	the	DET
american_scientific_journal-4355	250	11	appearance	appearance	NOUN
american_scientific_journal-4355	250	12	of	of	ADP
american_scientific_journal-4355	250	13	emt	emt	PROPN
american_scientific_journal-4355	250	14	markers	marker	NOUN
american_scientific_journal-4355	250	15	[	[	X
american_scientific_journal-4355	250	16	52	52	NUM
american_scientific_journal-4355	250	17	]	]	PUNCT
american_scientific_journal-4355	250	18	.	.	PUNCT
american_scientific_journal-4355	251	1	there	there	PRON
american_scientific_journal-4355	251	2	is	be	VERB
american_scientific_journal-4355	251	3	also	also	ADV
american_scientific_journal-4355	251	4	the	the	DET
american_scientific_journal-4355	251	5	generation	generation	NOUN
american_scientific_journal-4355	251	6	of	of	ADP
american_scientific_journal-4355	251	7	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	251	8	by	by	ADP
american_scientific_journal-4355	251	9	the	the	DET
american_scientific_journal-4355	251	10	proximal	proximal	ADJ
american_scientific_journal-4355	251	11	tubular	tubular	ADJ
american_scientific_journal-4355	251	12	epithelial	epithelial	ADJ
american_scientific_journal-4355	251	13	cells	cell	NOUN
american_scientific_journal-4355	251	14	via	via	ADP
american_scientific_journal-4355	251	15	emt[49	emt[49	NOUN
american_scientific_journal-4355	251	16	]	]	PUNCT
american_scientific_journal-4355	251	17	.	.	PUNCT
american_scientific_journal-4355	252	1	in	in	ADP
american_scientific_journal-4355	252	2	addition	addition	NOUN
american_scientific_journal-4355	252	3	,	,	PUNCT
american_scientific_journal-4355	252	4	there	there	PRON
american_scientific_journal-4355	252	5	is	be	VERB
american_scientific_journal-4355	252	6	evidence	evidence	NOUN
american_scientific_journal-4355	252	7	in‐vitro	in‐vitro	VERB
american_scientific_journal-4355	252	8	that	that	SCONJ
american_scientific_journal-4355	252	9	emt	emt	PROPN
american_scientific_journal-4355	252	10	phenotypes	phenotype	NOUN
american_scientific_journal-4355	252	11	occur	occur	VERB
american_scientific_journal-4355	252	12	in	in	ADP
american_scientific_journal-4355	252	13	different	different	ADJ
american_scientific_journal-4355	252	14	non‐malignant	non‐malignant	ADJ
american_scientific_journal-4355	252	15	epithelial	epithelial	ADJ
american_scientific_journal-4355	252	16	cells	cell	NOUN
american_scientific_journal-4355	252	17	of	of	ADP
american_scientific_journal-4355	252	18	different	different	ADJ
american_scientific_journal-4355	252	19	origin	origin	NOUN
american_scientific_journal-4355	252	20	.	.	PUNCT
american_scientific_journal-4355	253	1	this	this	PRON
american_scientific_journal-4355	253	2	includes	include	VERB
american_scientific_journal-4355	253	3	renal	renal	ADJ
american_scientific_journal-4355	253	4	,	,	PUNCT
american_scientific_journal-4355	253	5	hepatic	hepatic	ADJ
american_scientific_journal-4355	253	6	and	and	CCONJ
american_scientific_journal-4355	253	7	pulmonary	pulmonary	ADJ
american_scientific_journal-4355	253	8	cells	cell	NOUN
american_scientific_journal-4355	253	9	in	in	ADP
american_scientific_journal-4355	253	10	which	which	PRON
american_scientific_journal-4355	253	11	a	a	DET
american_scientific_journal-4355	253	12	process	process	NOUN
american_scientific_journal-4355	253	13	associated	associate	VERB
american_scientific_journal-4355	253	14	with	with	ADP
american_scientific_journal-4355	253	15	the	the	DET
american_scientific_journal-4355	253	16	expression	expression	NOUN
american_scientific_journal-4355	253	17	of	of	ADP
american_scientific_journal-4355	253	18	mesenchymal	mesenchymal	ADJ
american_scientific_journal-4355	253	19	marker	marker	NOUN
american_scientific_journal-4355	253	20	proteins	protein	NOUN
american_scientific_journal-4355	253	21	which	which	PRON
american_scientific_journal-4355	253	22	can	can	AUX
american_scientific_journal-4355	253	23	be	be	AUX
american_scientific_journal-4355	253	24	induced	induce	VERB
american_scientific_journal-4355	253	25	by	by	ADP
american_scientific_journal-4355	253	26	different	different	ADJ
american_scientific_journal-4355	253	27	stimuli	stimulus	NOUN
american_scientific_journal-4355	253	28	as	as	ADP
american_scientific_journal-4355	253	29	tgf	tgf	PROPN
american_scientific_journal-4355	253	30	-	-	PUNCT
american_scientific_journal-4355	253	31	β	β	PROPN
american_scientific_journal-4355	253	32	and	and	CCONJ
american_scientific_journal-4355	253	33	proteinase	proteinase	NOUN
american_scientific_journal-4355	253	34	-	-	PUNCT
american_scientific_journal-4355	253	35	activated	activate	VERB
american_scientific_journal-4355	253	36	receptors	receptor	NOUN
american_scientific_journal-4355	253	37	(	(	PUNCT
american_scientific_journal-4355	253	38	pars	par	NOUN
american_scientific_journal-4355	253	39	)	)	PUNCT
american_scientific_journal-4355	253	40	.	.	PUNCT
american_scientific_journal-4355	254	1	[	[	X
american_scientific_journal-4355	254	2	53	53	NUM
american_scientific_journal-4355	254	3	]	]	PUNCT
american_scientific_journal-4355	254	4	.	.	PUNCT
american_scientific_journal-4355	255	1	tgf	tgf	PROPN
american_scientific_journal-4355	255	2	-	-	PUNCT
american_scientific_journal-4355	255	3	β	β	PROPN
american_scientific_journal-4355	255	4	,	,	PUNCT
american_scientific_journal-4355	255	5	α	α	NOUN
american_scientific_journal-4355	255	6	-	-	PUNCT
american_scientific_journal-4355	255	7	sma	sma	NOUN
american_scientific_journal-4355	255	8	and	and	CCONJ
american_scientific_journal-4355	255	9	e	e	NOUN
american_scientific_journal-4355	255	10	-	-	NOUN
american_scientific_journal-4355	255	11	cadherin	cadherin	NOUN
american_scientific_journal-4355	255	12	have	have	VERB
american_scientific_journal-4355	255	13	a	a	DET
american_scientific_journal-4355	255	14	relationship	relationship	NOUN
american_scientific_journal-4355	255	15	with	with	ADP
american_scientific_journal-4355	255	16	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	255	17	regarding	regard	VERB
american_scientific_journal-4355	255	18	its	its	PRON
american_scientific_journal-4355	255	19	expressions	expression	NOUN
american_scientific_journal-4355	255	20	and	and	CCONJ
american_scientific_journal-4355	255	21	knock	knock	NOUN
american_scientific_journal-4355	255	22	-	-	PUNCT
american_scientific_journal-4355	255	23	down	down	NOUN
american_scientific_journal-4355	255	24	.	.	PUNCT
american_scientific_journal-4355	256	1	all	all	PRON
american_scientific_journal-4355	256	2	of	of	ADP
american_scientific_journal-4355	256	3	these	these	PRON
american_scientific_journal-4355	256	4	subsequently	subsequently	ADV
american_scientific_journal-4355	256	5	have	have	VERB
american_scientific_journal-4355	256	6	an	an	DET
american_scientific_journal-4355	256	7	impact	impact	NOUN
american_scientific_journal-4355	256	8	on	on	ADP
american_scientific_journal-4355	256	9	hk2	hk2	PROPN
american_scientific_journal-4355	256	10	cells	cell	NOUN
american_scientific_journal-4355	256	11	.	.	PUNCT
american_scientific_journal-4355	257	1	tgf	tgf	PROPN
american_scientific_journal-4355	257	2	-	-	PUNCT
american_scientific_journal-4355	257	3	β	β	PROPN
american_scientific_journal-4355	257	4	produced	produce	VERB
american_scientific_journal-4355	257	5	a	a	DET
american_scientific_journal-4355	257	6	high	high	ADJ
american_scientific_journal-4355	257	7	level	level	NOUN
american_scientific_journal-4355	257	8	of	of	ADP
american_scientific_journal-4355	257	9	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	257	10	expression	expression	NOUN
american_scientific_journal-4355	257	11	,	,	PUNCT
american_scientific_journal-4355	257	12	and	and	CCONJ
american_scientific_journal-4355	257	13	this	this	PRON
american_scientific_journal-4355	257	14	was	be	AUX
american_scientific_journal-4355	257	15	shown	show	VERB
american_scientific_journal-4355	257	16	in	in	ADP
american_scientific_journal-4355	257	17	the	the	DET
american_scientific_journal-4355	257	18	previous	previous	ADJ
american_scientific_journal-4355	257	19	chapters	chapter	NOUN
american_scientific_journal-4355	257	20	but	but	CCONJ
american_scientific_journal-4355	257	21	when	when	SCONJ
american_scientific_journal-4355	257	22	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	257	23	knocked	knock	VERB
american_scientific_journal-4355	257	24	-	-	PUNCT
american_scientific_journal-4355	257	25	down	down	ADP
american_scientific_journal-4355	257	26	,	,	PUNCT
american_scientific_journal-4355	257	27	its	its	PRON
american_scientific_journal-4355	257	28	expression	expression	NOUN
american_scientific_journal-4355	257	29	dropped	drop	VERB
american_scientific_journal-4355	257	30	down	down	ADP
american_scientific_journal-4355	257	31	,	,	PUNCT
american_scientific_journal-4355	257	32	that	that	PRON
american_scientific_journal-4355	257	33	means	mean	VERB
american_scientific_journal-4355	257	34	tgf	tgf	PROPN
american_scientific_journal-4355	257	35	-	-	PUNCT
american_scientific_journal-4355	257	36	β	β	X
american_scientific_journal-4355	257	37	biological	biological	ADJ
american_scientific_journal-4355	257	38	activity	activity	NOUN
american_scientific_journal-4355	257	39	can	can	AUX
american_scientific_journal-4355	257	40	be	be	AUX
american_scientific_journal-4355	257	41	controlled	control	VERB
american_scientific_journal-4355	257	42	.	.	PUNCT
american_scientific_journal-4355	258	1	transforming	transform	VERB
american_scientific_journal-4355	258	2	growth	growth	NOUN
american_scientific_journal-4355	258	3	factor	factor	NOUN
american_scientific_journal-4355	258	4	-	-	PUNCT
american_scientific_journal-4355	258	5	β	β	X
american_scientific_journal-4355	258	6	(	(	PUNCT
american_scientific_journal-4355	258	7	tgf	tgf	PROPN
american_scientific_journal-4355	258	8	-	-	PUNCT
american_scientific_journal-4355	258	9	β	β	NOUN
american_scientific_journal-4355	258	10	)	)	PUNCT
american_scientific_journal-4355	258	11	is	be	AUX
american_scientific_journal-4355	258	12	a	a	DET
american_scientific_journal-4355	258	13	key	key	ADJ
american_scientific_journal-4355	258	14	mediator	mediator	NOUN
american_scientific_journal-4355	258	15	in	in	ADP
american_scientific_journal-4355	258	16	the	the	DET
american_scientific_journal-4355	258	17	pathogenesis	pathogenesis	NOUN
american_scientific_journal-4355	258	18	of	of	ADP
american_scientific_journal-4355	258	19	renal	renal	ADJ
american_scientific_journal-4355	258	20	diseases	disease	NOUN
american_scientific_journal-4355	258	21	but	but	CCONJ
american_scientific_journal-4355	258	22	tgf	tgf	PROPN
american_scientific_journal-4355	258	23	-	-	PUNCT
american_scientific_journal-4355	258	24	β	β	NOUN
american_scientific_journal-4355	258	25	activity	activity	NOUN
american_scientific_journal-4355	258	26	has	have	AUX
american_scientific_journal-4355	258	27	been	be	AUX
american_scientific_journal-4355	258	28	reduced	reduce	VERB
american_scientific_journal-4355	258	29	during	during	ADP
american_scientific_journal-4355	258	30	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	258	31	knock	knock	PROPN
american_scientific_journal-4355	258	32	-	-	PUNCT
american_scientific_journal-4355	258	33	down	down	NOUN
american_scientific_journal-4355	258	34	,	,	PUNCT
american_scientific_journal-4355	258	35	so	so	SCONJ
american_scientific_journal-4355	258	36	kidney	kidney	NOUN
american_scientific_journal-4355	258	37	diseases	disease	NOUN
american_scientific_journal-4355	258	38	and	and	CCONJ
american_scientific_journal-4355	258	39	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	258	40	can	can	AUX
american_scientific_journal-4355	258	41	be	be	AUX
american_scientific_journal-4355	258	42	reduced	reduce	VERB
american_scientific_journal-4355	258	43	.	.	PUNCT
american_scientific_journal-4355	259	1	this	this	DET
american_scientific_journal-4355	259	2	renoprotective	renoprotective	ADJ
american_scientific_journal-4355	259	3	advantage	advantage	NOUN
american_scientific_journal-4355	259	4	of	of	ADP
american_scientific_journal-4355	259	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	259	6	is	be	AUX
american_scientific_journal-4355	259	7	induced	induce	VERB
american_scientific_journal-4355	259	8	by	by	ADP
american_scientific_journal-4355	259	9	its	its	PRON
american_scientific_journal-4355	259	10	soluble	soluble	ADJ
american_scientific_journal-4355	259	11	form	form	NOUN
american_scientific_journal-4355	259	12	which	which	PRON
american_scientific_journal-4355	259	13	binds	bind	VERB
american_scientific_journal-4355	259	14	tgf	tgf	PROPN
american_scientific_journal-4355	259	15	-	-	PUNCT
american_scientific_journal-4355	259	16	β	β	PROPN
american_scientific_journal-4355	259	17	with	with	ADP
american_scientific_journal-4355	259	18	the	the	DET
american_scientific_journal-4355	259	19	high	high	ADJ
american_scientific_journal-4355	259	20	affinity	affinity	NOUN
american_scientific_journal-4355	259	21	of	of	ADP
american_scientific_journal-4355	259	22	the	the	DET
american_scientific_journal-4355	259	23	membrane	membrane	NOUN
american_scientific_journal-4355	259	24	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	259	25	,	,	PUNCT
american_scientific_journal-4355	259	26	but	but	CCONJ
american_scientific_journal-4355	259	27	actions	action	NOUN
american_scientific_journal-4355	260	1	[	[	X
american_scientific_journal-4355	260	2	instead	instead	ADV
american_scientific_journal-4355	260	3	of	of	ADP
american_scientific_journal-4355	260	4	presenting	present	VERB
american_scientific_journal-4355	260	5	it	it	PRON
american_scientific_journal-4355	260	6	to	to	ADP
american_scientific_journal-4355	260	7	the	the	DET
american_scientific_journal-4355	260	8	type	type	NOUN
american_scientific_journal-4355	260	9	ii	ii	NOUN
american_scientific_journal-4355	260	10	receptor	receptor	NOUN
american_scientific_journal-4355	260	11	,	,	PUNCT
american_scientific_journal-4355	260	12	soluble	soluble	ADJ
american_scientific_journal-4355	260	13	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	260	14	sequesters	sequester	VERB
american_scientific_journal-4355	260	15	it	it	PRON
american_scientific_journal-4355	260	16	and	and	CCONJ
american_scientific_journal-4355	260	17	thus	thus	ADV
american_scientific_journal-4355	260	18	neutralizes	neutralize	VERB
american_scientific_journal-4355	260	19	its	its	PRON
american_scientific_journal-4355	260	20	54	54	NUM
american_scientific_journal-4355	260	21	]	]	PUNCT
american_scientific_journal-4355	260	22	.	.	PUNCT
american_scientific_journal-4355	261	1	e	e	X
american_scientific_journal-4355	261	2	-	-	NOUN
american_scientific_journal-4355	261	3	cadherin	cadherin	NOUN
american_scientific_journal-4355	261	4	and	and	CCONJ
american_scientific_journal-4355	261	5	α	α	NOUN
american_scientific_journal-4355	261	6	-	-	PUNCT
american_scientific_journal-4355	261	7	sma	sma	NOUN
american_scientific_journal-4355	261	8	expression	expression	NOUN
american_scientific_journal-4355	261	9	can	can	AUX
american_scientific_journal-4355	261	10	also	also	ADV
american_scientific_journal-4355	261	11	be	be	AUX
american_scientific_journal-4355	261	12	explored	explore	VERB
american_scientific_journal-4355	261	13	when	when	SCONJ
american_scientific_journal-4355	261	14	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	261	15	knocked	knock	VERB
american_scientific_journal-4355	261	16	-	-	PUNCT
american_scientific_journal-4355	261	17	down	down	NOUN
american_scientific_journal-4355	261	18	.	.	PUNCT
american_scientific_journal-4355	262	1	that	that	PRON
american_scientific_journal-4355	262	2	was	be	AUX
american_scientific_journal-4355	262	3	evident	evident	ADJ
american_scientific_journal-4355	262	4	when	when	SCONJ
american_scientific_journal-4355	262	5	samples	sample	NOUN
american_scientific_journal-4355	262	6	compared	compare	VERB
american_scientific_journal-4355	262	7	to	to	ADP
american_scientific_journal-4355	262	8	the	the	DET
american_scientific_journal-4355	262	9	1st	1st	ADJ
american_scientific_journal-4355	262	10	scramble	scramble	NOUN
american_scientific_journal-4355	262	11	did	do	AUX
american_scientific_journal-4355	262	12	occur	occur	VERB
american_scientific_journal-4355	262	13	during	during	ADP
american_scientific_journal-4355	262	14	emt	emt	PROPN
american_scientific_journal-4355	262	15	,	,	PUNCT
american_scientific_journal-4355	262	16	with	with	ADP
american_scientific_journal-4355	262	17	e	e	NOUN
american_scientific_journal-4355	262	18	-	-	NOUN
american_scientific_journal-4355	262	19	cadherin	cadherin	NOUN
american_scientific_journal-4355	262	20	expression	expression	NOUN
american_scientific_journal-4355	262	21	reduced	reduce	VERB
american_scientific_journal-4355	262	22	while	while	SCONJ
american_scientific_journal-4355	262	23	α	α	NOUN
american_scientific_journal-4355	262	24	-	-	PUNCT
american_scientific_journal-4355	262	25	sma	sma	NOUN
american_scientific_journal-4355	262	26	expression	expression	NOUN
american_scientific_journal-4355	262	27	was	be	AUX
american_scientific_journal-4355	262	28	increased	increase	VERB
american_scientific_journal-4355	262	29	and	and	CCONJ
american_scientific_journal-4355	262	30	that	that	PRON
american_scientific_journal-4355	262	31	supports	support	VERB
american_scientific_journal-4355	262	32	emt	emt	PROPN
american_scientific_journal-4355	262	33	as	as	ADP
american_scientific_journal-4355	262	34	an	an	DET
american_scientific_journal-4355	262	35	effect	effect	NOUN
american_scientific_journal-4355	262	36	of	of	ADP
american_scientific_journal-4355	262	37	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	262	38	knock	knock	VERB
american_scientific_journal-4355	262	39	-	-	PUNCT
american_scientific_journal-4355	262	40	down	down	NOUN
american_scientific_journal-4355	262	41	,	,	PUNCT
american_scientific_journal-4355	262	42	this	this	DET
american_scientific_journal-4355	262	43	effect	effect	NOUN
american_scientific_journal-4355	262	44	was	be	AUX
american_scientific_journal-4355	262	45	found	find	VERB
american_scientific_journal-4355	262	46	to	to	PART
american_scientific_journal-4355	262	47	be	be	AUX
american_scientific_journal-4355	262	48	mild	mild	ADJ
american_scientific_journal-4355	262	49	,	,	PUNCT
american_scientific_journal-4355	262	50	and	and	CCONJ
american_scientific_journal-4355	262	51	this	this	PRON
american_scientific_journal-4355	262	52	is	be	AUX
american_scientific_journal-4355	262	53	where	where	SCONJ
american_scientific_journal-4355	262	54	the	the	DET
american_scientific_journal-4355	262	55	role	role	NOUN
american_scientific_journal-4355	262	56	of	of	ADP
american_scientific_journal-4355	262	57	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	262	58	comes	come	VERB
american_scientific_journal-4355	262	59	,	,	PUNCT
american_scientific_journal-4355	262	60	its	its	PRON
american_scientific_journal-4355	262	61	presence	presence	NOUN
american_scientific_journal-4355	262	62	will	will	AUX
american_scientific_journal-4355	262	63	reduce	reduce	VERB
american_scientific_journal-4355	262	64	emt	emt	ADJ
american_scientific_journal-4355	262	65	effect	effect	NOUN
american_scientific_journal-4355	262	66	.	.	PUNCT
american_scientific_journal-4355	263	1	once	once	SCONJ
american_scientific_journal-4355	263	2	the	the	DET
american_scientific_journal-4355	263	3	relationship	relationship	NOUN
american_scientific_journal-4355	263	4	of	of	ADP
american_scientific_journal-4355	263	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	263	6	and	and	CCONJ
american_scientific_journal-4355	263	7	tgf	tgf	PROPN
american_scientific_journal-4355	263	8	-	-	PUNCT
american_scientific_journal-4355	263	9	β	β	PROPN
american_scientific_journal-4355	263	10	signalling	signal	VERB
american_scientific_journal-4355	263	11	was	be	AUX
american_scientific_journal-4355	263	12	determined	determine	VERB
american_scientific_journal-4355	263	13	and	and	CCONJ
american_scientific_journal-4355	263	14	tgf	tgf	PROPN
american_scientific_journal-4355	263	15	-	-	PUNCT
american_scientific_journal-4355	263	16	β	β	PROPN
american_scientific_journal-4355	263	17	is	be	AUX
american_scientific_journal-4355	263	18	an	an	DET
american_scientific_journal-4355	263	19	inducer	inducer	NOUN
american_scientific_journal-4355	263	20	of	of	ADP
american_scientific_journal-4355	263	21	pai-1	pai-1	ADJ
american_scientific_journal-4355	263	22	,	,	PUNCT
american_scientific_journal-4355	263	23	betaglycan̕s	betaglycan̕s	PROPN
american_scientific_journal-4355	263	24	relationship	relationship	NOUN
american_scientific_journal-4355	263	25	with	with	ADP
american_scientific_journal-4355	263	26	pai-1	pai-1	NUM
american_scientific_journal-4355	263	27	could	could	AUX
american_scientific_journal-4355	263	28	also	also	ADV
american_scientific_journal-4355	263	29	be	be	AUX
american_scientific_journal-4355	263	30	studied	study	VERB
american_scientific_journal-4355	263	31	,	,	PUNCT
american_scientific_journal-4355	263	32	and	and	CCONJ
american_scientific_journal-4355	263	33	there	there	PRON
american_scientific_journal-4355	263	34	was	be	VERB
american_scientific_journal-4355	263	35	no	no	DET
american_scientific_journal-4355	263	36	direct	direct	ADJ
american_scientific_journal-4355	263	37	action	action	NOUN
american_scientific_journal-4355	263	38	,	,	PUNCT
american_scientific_journal-4355	263	39	but	but	CCONJ
american_scientific_journal-4355	263	40	when	when	SCONJ
american_scientific_journal-4355	263	41	tgf	tgf	PROPN
american_scientific_journal-4355	263	42	-	-	PUNCT
american_scientific_journal-4355	263	43	β	β	PROPN
american_scientific_journal-4355	263	44	was	be	AUX
american_scientific_journal-4355	263	45	applied	apply	VERB
american_scientific_journal-4355	263	46	,	,	PUNCT
american_scientific_journal-4355	263	47	pai-1	pai-1	NUM
american_scientific_journal-4355	263	48	expression	expression	NOUN
american_scientific_journal-4355	263	49	increased	increase	VERB
american_scientific_journal-4355	263	50	and	and	CCONJ
american_scientific_journal-4355	263	51	that	that	PRON
american_scientific_journal-4355	263	52	supports	support	VERB
american_scientific_journal-4355	263	53	the	the	DET
american_scientific_journal-4355	263	54	argument	argument	NOUN
american_scientific_journal-4355	263	55	that	that	SCONJ
american_scientific_journal-4355	263	56	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	263	57	has	have	AUX
american_scientific_journal-4355	263	58	no	no	DET
american_scientific_journal-4355	263	59	relation	relation	NOUN
american_scientific_journal-4355	263	60	with	with	ADP
american_scientific_journal-4355	263	61	pai-1	pai-1	NUM
american_scientific_journal-4355	263	62	but	but	CCONJ
american_scientific_journal-4355	263	63	a	a	DET
american_scientific_journal-4355	263	64	direct	direct	ADJ
american_scientific_journal-4355	263	65	action	action	NOUN
american_scientific_journal-4355	263	66	with	with	ADP
american_scientific_journal-4355	263	67	tgf	tgf	PROPN
american_scientific_journal-4355	263	68	-	-	PUNCT
american_scientific_journal-4355	263	69	β	β	PROPN
american_scientific_journal-4355	263	70	which	which	PRON
american_scientific_journal-4355	263	71	is	be	AUX
american_scientific_journal-4355	263	72	the	the	DET
american_scientific_journal-4355	263	73	mean	mean	ADJ
american_scientific_journal-4355	263	74	inducer	inducer	NOUN
american_scientific_journal-4355	263	75	of	of	ADP
american_scientific_journal-4355	263	76	pai	pai	PROPN
american_scientific_journal-4355	263	77	and	and	CCONJ
american_scientific_journal-4355	263	78	there	there	PRON
american_scientific_journal-4355	263	79	might	might	AUX
american_scientific_journal-4355	263	80	be	be	AUX
american_scientific_journal-4355	263	81	other	other	ADJ
american_scientific_journal-4355	263	82	mechanisms	mechanism	NOUN
american_scientific_journal-4355	263	83	have	have	AUX
american_scientific_journal-4355	263	84	been	be	AUX
american_scientific_journal-4355	263	85	involved	involve	VERB
american_scientific_journal-4355	263	86	as	as	SCONJ
american_scientific_journal-4355	263	87	cells	cell	NOUN
american_scientific_journal-4355	263	88	were	be	AUX
american_scientific_journal-4355	263	89	more	more	ADV
american_scientific_journal-4355	263	90	reactive	reactive	ADJ
american_scientific_journal-4355	263	91	to	to	ADP
american_scientific_journal-4355	263	92	tgf	tgf	PROPN
american_scientific_journal-4355	263	93	-	-	PUNCT
american_scientific_journal-4355	263	94	β	β	NOUN
american_scientific_journal-4355	263	95	.	.	PUNCT
american_scientific_journal-4355	264	1	it	it	PRON
american_scientific_journal-4355	264	2	has	have	AUX
american_scientific_journal-4355	264	3	clearly	clearly	ADV
american_scientific_journal-4355	264	4	been	be	AUX
american_scientific_journal-4355	264	5	shown	show	VERB
american_scientific_journal-4355	264	6	in	in	ADP
american_scientific_journal-4355	264	7	this	this	DET
american_scientific_journal-4355	264	8	chapter	chapter	NOUN
american_scientific_journal-4355	264	9	that	that	PRON
american_scientific_journal-4355	264	10	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	264	11	has	have	VERB
american_scientific_journal-4355	264	12	an	an	DET
american_scientific_journal-4355	264	13	important	important	ADJ
american_scientific_journal-4355	264	14	role	role	NOUN
american_scientific_journal-4355	264	15	in	in	ADP
american_scientific_journal-4355	264	16	reducing	reduce	VERB
american_scientific_journal-4355	264	17	epithelial	epithelial	ADJ
american_scientific_journal-4355	264	18	-	-	PUNCT
american_scientific_journal-4355	264	19	mesenchymal	mesenchymal	NOUN
american_scientific_journal-4355	264	20	transformation	transformation	NOUN
american_scientific_journal-4355	264	21	(	(	PUNCT
american_scientific_journal-4355	264	22	emt	emt	PROPN
american_scientific_journal-4355	264	23	)	)	PUNCT
american_scientific_journal-4355	264	24	.	.	PUNCT
american_scientific_journal-4355	265	1	3	3	X
american_scientific_journal-4355	265	2	.	.	X
american_scientific_journal-4355	265	3	general	general	ADJ
american_scientific_journal-4355	265	4	discussion	discussion	NOUN
american_scientific_journal-4355	265	5	the	the	DET
american_scientific_journal-4355	265	6	aim	aim	NOUN
american_scientific_journal-4355	265	7	of	of	ADP
american_scientific_journal-4355	265	8	this	this	DET
american_scientific_journal-4355	265	9	thesis	thesis	NOUN
american_scientific_journal-4355	265	10	was	be	AUX
american_scientific_journal-4355	265	11	to	to	PART
american_scientific_journal-4355	265	12	explore	explore	VERB
american_scientific_journal-4355	265	13	the	the	DET
american_scientific_journal-4355	265	14	role	role	NOUN
american_scientific_journal-4355	265	15	of	of	ADP
american_scientific_journal-4355	265	16	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	265	17	as	as	ADP
american_scientific_journal-4355	265	18	a	a	DET
american_scientific_journal-4355	265	19	potential	potential	ADJ
american_scientific_journal-4355	265	20	regulator	regulator	NOUN
american_scientific_journal-4355	265	21	of	of	ADP
american_scientific_journal-4355	265	22	tgf	tgf	PROPN
american_scientific_journal-4355	265	23	-	-	PUNCT
american_scientific_journal-4355	265	24	β	β	PROPN
american_scientific_journal-4355	265	25	signalling	signal	VERB
american_scientific_journal-4355	265	26	in	in	ADP
american_scientific_journal-4355	265	27	the	the	DET
american_scientific_journal-4355	265	28	kidney	kidney	NOUN
american_scientific_journal-4355	265	29	.	.	PUNCT
american_scientific_journal-4355	266	1	it	it	PRON
american_scientific_journal-4355	266	2	has	have	AUX
american_scientific_journal-4355	266	3	been	be	AUX
american_scientific_journal-4355	266	4	found	find	VERB
american_scientific_journal-4355	266	5	that	that	SCONJ
american_scientific_journal-4355	266	6	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	266	7	has	have	AUX
american_scientific_journal-4355	266	8	been	be	AUX
american_scientific_journal-4355	266	9	expressed	express	VERB
american_scientific_journal-4355	266	10	by	by	ADP
american_scientific_journal-4355	266	11	human	human	ADJ
american_scientific_journal-4355	266	12	ptc	ptc	PROPN
american_scientific_journal-4355	266	13	in	in	ADP
american_scientific_journal-4355	266	14	culture	culture	NOUN
american_scientific_journal-4355	266	15	either	either	CCONJ
american_scientific_journal-4355	266	16	without	without	ADP
american_scientific_journal-4355	266	17	stimulation	stimulation	NOUN
american_scientific_journal-4355	266	18	or	or	CCONJ
american_scientific_journal-4355	266	19	when	when	SCONJ
american_scientific_journal-4355	266	20	ptc	ptc	PROPN
american_scientific_journal-4355	266	21	stimulated	stimulate	VERB
american_scientific_journal-4355	266	22	at	at	ADP
american_scientific_journal-4355	266	23	the	the	DET
american_scientific_journal-4355	266	24	level	level	NOUN
american_scientific_journal-4355	266	25	of	of	ADP
american_scientific_journal-4355	266	26	the	the	DET
american_scientific_journal-4355	266	27	mrna	mrna	NOUN
american_scientific_journal-4355	266	28	or	or	CCONJ
american_scientific_journal-4355	266	29	at	at	ADP
american_scientific_journal-4355	266	30	protein	protein	NOUN
american_scientific_journal-4355	266	31	level	level	NOUN
american_scientific_journal-4355	266	32	and	and	CCONJ
american_scientific_journal-4355	266	33	this	this	PRON
american_scientific_journal-4355	266	34	could	could	AUX
american_scientific_journal-4355	266	35	be	be	AUX
american_scientific_journal-4355	266	36	inducible	inducible	ADJ
american_scientific_journal-4355	266	37	by	by	ADP
american_scientific_journal-4355	266	38	the	the	DET
american_scientific_journal-4355	266	39	cytokines	cytokine	NOUN
american_scientific_journal-4355	266	40	namely	namely	ADV
american_scientific_journal-4355	266	41	il-1	il-1	ADP
american_scientific_journal-4355	266	42	,	,	PUNCT
american_scientific_journal-4355	266	43	il-6	il-6	NUM
american_scientific_journal-4355	266	44	and	and	CCONJ
american_scientific_journal-4355	266	45	tgf	tgf	PROPN
american_scientific_journal-4355	266	46	-	-	PUNCT
american_scientific_journal-4355	266	47	β	β	NOUN
american_scientific_journal-4355	266	48	,	,	PUNCT
american_scientific_journal-4355	266	49	this	this	PRON
american_scientific_journal-4355	266	50	emphasises	emphasise	VERB
american_scientific_journal-4355	266	51	the	the	DET
american_scientific_journal-4355	266	52	potential	potential	ADJ
american_scientific_journal-4355	266	53	importance	importance	NOUN
american_scientific_journal-4355	266	54	of	of	ADP
american_scientific_journal-4355	266	55	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	266	56	in	in	ADP
american_scientific_journal-4355	266	57	ptc	ptc	PROPN
american_scientific_journal-4355	266	58	(	(	PUNCT
american_scientific_journal-4355	266	59	proximal	proximal	ADJ
american_scientific_journal-4355	266	60	tubular	tubular	ADJ
american_scientific_journal-4355	266	61	cells	cell	NOUN
american_scientific_journal-4355	266	62	)	)	PUNCT
american_scientific_journal-4355	266	63	as	as	ADP
american_scientific_journal-4355	266	64	a	a	DET
american_scientific_journal-4355	266	65	contributor	contributor	NOUN
american_scientific_journal-4355	266	66	to	to	ADP
american_scientific_journal-4355	266	67	the	the	DET
american_scientific_journal-4355	266	68	pathogenesis	pathogenesis	NOUN
american_scientific_journal-4355	266	69	of	of	ADP
american_scientific_journal-4355	266	70	renal	renal	ADJ
american_scientific_journal-4355	266	71	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	266	72	either	either	CCONJ
american_scientific_journal-4355	266	73	by	by	ADP
american_scientific_journal-4355	266	74	alteration	alteration	NOUN
american_scientific_journal-4355	266	75	of	of	ADP
american_scientific_journal-4355	266	76	extracellular	extracellular	ADJ
american_scientific_journal-4355	266	77	matrix	matrix	NOUN
american_scientific_journal-4355	266	78	or	or	CCONJ
american_scientific_journal-4355	266	79	by	by	ADP
american_scientific_journal-4355	266	80	production	production	NOUN
american_scientific_journal-4355	266	81	of	of	ADP
american_scientific_journal-4355	266	82	profibrotic	profibrotic	ADJ
american_scientific_journal-4355	266	83	cytokines	cytokine	NOUN
american_scientific_journal-4355	266	84	such	such	ADJ
american_scientific_journal-4355	266	85	as	as	ADP
american_scientific_journal-4355	266	86	il-1	il-1	X
american_scientific_journal-4355	266	87	,	,	PUNCT
american_scientific_journal-4355	266	88	il-6	il-6	NUM
american_scientific_journal-4355	266	89	and	and	CCONJ
american_scientific_journal-4355	266	90	tgf	tgf	PROPN
american_scientific_journal-4355	266	91	-	-	PUNCT
american_scientific_journal-4355	266	92	β	β	NOUN
american_scientific_journal-4355	266	93	.	.	PUNCT
american_scientific_journal-4355	267	1	these	these	DET
american_scientific_journal-4355	267	2	cytokines	cytokine	NOUN
american_scientific_journal-4355	267	3	have	have	VERB
american_scientific_journal-4355	267	4	significant	significant	ADJ
american_scientific_journal-4355	267	5	cell	cell	NOUN
american_scientific_journal-4355	267	6	interaction	interaction	NOUN
american_scientific_journal-4355	267	7	with	with	ADP
american_scientific_journal-4355	267	8	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	267	9	and	and	CCONJ
american_scientific_journal-4355	267	10	its	its	PRON
american_scientific_journal-4355	267	11	activation	activation	NOUN
american_scientific_journal-4355	267	12	,	,	PUNCT
american_scientific_journal-4355	267	13	and	and	CCONJ
american_scientific_journal-4355	267	14	therefore	therefore	ADV
american_scientific_journal-4355	267	15	provide	provide	VERB
american_scientific_journal-4355	267	16	different	different	ADJ
american_scientific_journal-4355	267	17	degrees	degree	NOUN
american_scientific_journal-4355	267	18	of	of	ADP
american_scientific_journal-4355	267	19	expression	expression	NOUN
american_scientific_journal-4355	267	20	.	.	PUNCT
american_scientific_journal-4355	268	1	since	since	SCONJ
american_scientific_journal-4355	268	2	hk2	hk2	PROPN
american_scientific_journal-4355	268	3	cells	cell	NOUN
american_scientific_journal-4355	268	4	express	express	VERB
american_scientific_journal-4355	268	5	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	268	6	,	,	PUNCT
american_scientific_journal-4355	268	7	so	so	ADV
american_scientific_journal-4355	268	8	do	do	VERB
american_scientific_journal-4355	268	9	the	the	DET
american_scientific_journal-4355	268	10	cytokines	cytokine	NOUN
american_scientific_journal-4355	268	11	(	(	PUNCT
american_scientific_journal-4355	268	12	il-1	il-1	NUM
american_scientific_journal-4355	268	13	,	,	PUNCT
american_scientific_journal-4355	268	14	il-6	il-6	NUM
american_scientific_journal-4355	268	15	and	and	CCONJ
american_scientific_journal-4355	268	16	tgf	tgf	PROPN
american_scientific_journal-4355	268	17	-	-	PUNCT
american_scientific_journal-4355	268	18	β	β	NOUN
american_scientific_journal-4355	268	19	)	)	PUNCT
american_scientific_journal-4355	268	20	,	,	PUNCT
american_scientific_journal-4355	268	21	this	this	DET
american_scientific_journal-4355	268	22	result	result	NOUN
american_scientific_journal-4355	268	23	supports	support	VERB
american_scientific_journal-4355	268	24	the	the	DET
american_scientific_journal-4355	268	25	argument	argument	NOUN
american_scientific_journal-4355	268	26	that	that	PRON
american_scientific_journal-4355	268	27	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	268	28	expression	expression	NOUN
american_scientific_journal-4355	268	29	is	be	AUX
american_scientific_journal-4355	268	30	essential	essential	ADJ
american_scientific_journal-4355	268	31	for	for	ADP
american_scientific_journal-4355	268	32	optimal	optimal	ADJ
american_scientific_journal-4355	268	33	tgf	tgf	NOUN
american_scientific_journal-4355	268	34	-	-	PUNCT
american_scientific_journal-4355	268	35	beta	beta	NOUN
american_scientific_journal-4355	268	36	signalling	signalling	NOUN
american_scientific_journal-4355	268	37	.	.	PUNCT
american_scientific_journal-4355	269	1	these	these	PRON
american_scientific_journal-4355	269	2	have	have	AUX
american_scientific_journal-4355	269	3	been	be	AUX
american_scientific_journal-4355	269	4	proved	prove	VERB
american_scientific_journal-4355	269	5	by	by	ADP
american_scientific_journal-4355	269	6	conventional	conventional	ADJ
american_scientific_journal-4355	269	7	pcr	pcr	NOUN
american_scientific_journal-4355	269	8	and	and	CCONJ
american_scientific_journal-4355	269	9	confirmed	confirm	VERB
american_scientific_journal-4355	269	10	by	by	ADP
american_scientific_journal-4355	269	11	q	q	NOUN
american_scientific_journal-4355	269	12	-	-	ADJ
american_scientific_journal-4355	269	13	pcr	pcr	ADJ
american_scientific_journal-4355	269	14	where	where	SCONJ
american_scientific_journal-4355	269	15	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	269	16	has	have	AUX
american_scientific_journal-4355	269	17	shown	show	VERB
american_scientific_journal-4355	269	18	a	a	DET
american_scientific_journal-4355	269	19	maximum	maximum	ADJ
american_scientific_journal-4355	269	20	expression	expression	NOUN
american_scientific_journal-4355	269	21	during	during	ADP
american_scientific_journal-4355	269	22	24	24	NUM
american_scientific_journal-4355	269	23	hours	hour	NOUN
american_scientific_journal-4355	269	24	.	.	PUNCT
american_scientific_journal-4355	270	1	other	other	ADJ
american_scientific_journal-4355	270	2	cells	cell	NOUN
american_scientific_journal-4355	270	3	such	such	ADJ
american_scientific_journal-4355	270	4	as	as	ADP
american_scientific_journal-4355	270	5	colon	colon	NOUN
american_scientific_journal-4355	270	6	goblet	goblet	NOUN
american_scientific_journal-4355	270	7	cells	cell	NOUN
american_scientific_journal-4355	270	8	express	express	VERB
american_scientific_journal-4355	270	9	normal	normal	ADJ
american_scientific_journal-4355	270	10	levels	level	NOUN
american_scientific_journal-4355	270	11	of	of	ADP
american_scientific_journal-4355	270	12	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	270	13	protein	protein	NOUN
american_scientific_journal-4355	270	14	[	[	X
american_scientific_journal-4355	270	15	55	55	NUM
american_scientific_journal-4355	270	16	]	]	PUNCT
american_scientific_journal-4355	270	17	,	,	PUNCT
american_scientific_journal-4355	270	18	cardiac	cardiac	ADJ
american_scientific_journal-4355	270	19	endothelial	endothelial	ADJ
american_scientific_journal-4355	270	20	cells	cell	NOUN
american_scientific_journal-4355	270	21	that	that	PRON
american_scientific_journal-4355	270	22	undergo	undergo	VERB
american_scientific_journal-4355	270	23	epithelial	epithelial	ADJ
american_scientific_journal-4355	270	24	-	-	PUNCT
american_scientific_journal-4355	270	25	mesenchymal	mesenchymal	NOUN
american_scientific_journal-4355	270	26	transformation	transformation	NOUN
american_scientific_journal-4355	270	27	express	express	ADJ
american_scientific_journal-4355	270	28	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	271	1	[	[	X
american_scientific_journal-4355	271	2	56	56	NUM
american_scientific_journal-4355	271	3	]	]	PUNCT
american_scientific_journal-4355	271	4	.	.	PUNCT
american_scientific_journal-4355	272	1	now	now	ADV
american_scientific_journal-4355	272	2	this	this	PRON
american_scientific_journal-4355	272	3	has	have	AUX
american_scientific_journal-4355	272	4	also	also	ADV
american_scientific_journal-4355	272	5	been	be	AUX
american_scientific_journal-4355	272	6	seen	see	VERB
american_scientific_journal-4355	272	7	with	with	ADP
american_scientific_journal-4355	272	8	hk2	hk2	PROPN
american_scientific_journal-4355	272	9	cells	cell	NOUN
american_scientific_journal-4355	272	10	of	of	ADP
american_scientific_journal-4355	272	11	the	the	DET
american_scientific_journal-4355	272	12	kidney	kidney	NOUN
american_scientific_journal-4355	272	13	.	.	PUNCT
american_scientific_journal-4355	273	1	on	on	ADP
american_scientific_journal-4355	273	2	the	the	DET
american_scientific_journal-4355	273	3	other	other	ADJ
american_scientific_journal-4355	273	4	hand	hand	NOUN
american_scientific_journal-4355	273	5	,	,	PUNCT
american_scientific_journal-4355	273	6	instead	instead	ADV
american_scientific_journal-4355	273	7	of	of	ADP
american_scientific_journal-4355	273	8	expression	expression	NOUN
american_scientific_journal-4355	273	9	,	,	PUNCT
american_scientific_journal-4355	273	10	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	273	11	can	can	AUX
american_scientific_journal-4355	273	12	be	be	AUX
american_scientific_journal-4355	273	13	knocked	knock	VERB
american_scientific_journal-4355	273	14	-	-	PUNCT
american_scientific_journal-4355	273	15	down	down	ADP
american_scientific_journal-4355	273	16	by	by	ADP
american_scientific_journal-4355	273	17	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	273	18	sirna	sirna	PROPN
american_scientific_journal-4355	273	19	transfection	transfection	NOUN
american_scientific_journal-4355	273	20	or	or	CCONJ
american_scientific_journal-4355	273	21	interference	interference	NOUN
american_scientific_journal-4355	273	22	with	with	ADP
american_scientific_journal-4355	273	23	its	its	PRON
american_scientific_journal-4355	273	24	heparin	heparin	ADJ
american_scientific_journal-4355	273	25	sulphate	sulphate	NOUN
american_scientific_journal-4355	273	26	composition	composition	NOUN
american_scientific_journal-4355	273	27	,	,	PUNCT
american_scientific_journal-4355	273	28	which	which	PRON
american_scientific_journal-4355	273	29	considered	consider	VERB
american_scientific_journal-4355	273	30	to	to	PART
american_scientific_journal-4355	273	31	be	be	AUX
american_scientific_journal-4355	273	32	as	as	ADP
american_scientific_journal-4355	273	33	a	a	DET
american_scientific_journal-4355	273	34	beneficial	beneficial	ADJ
american_scientific_journal-4355	273	35	effect	effect	NOUN
american_scientific_journal-4355	273	36	of	of	ADP
american_scientific_journal-4355	273	37	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	273	38	,	,	PUNCT
american_scientific_journal-4355	273	39	an	an	DET
american_scientific_journal-4355	273	40	example	example	NOUN
american_scientific_journal-4355	273	41	of	of	ADP
american_scientific_journal-4355	273	42	that	that	PRON
american_scientific_journal-4355	273	43	was	be	AUX
american_scientific_journal-4355	273	44	in	in	ADP
american_scientific_journal-4355	273	45	treating	treat	VERB
american_scientific_journal-4355	273	46	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	273	47	as	as	ADP
american_scientific_journal-4355	273	48	its	its	PRON
american_scientific_journal-4355	273	49	knock	knock	NOUN
american_scientific_journal-4355	273	50	-	-	PUNCT
american_scientific_journal-4355	273	51	down	down	ADP
american_scientific_journal-4355	273	52	reduce	reduce	VERB
american_scientific_journal-4355	273	53	tgf	tgf	PROPN
american_scientific_journal-4355	273	54	-	-	PUNCT
american_scientific_journal-4355	273	55	β	β	NOUN
american_scientific_journal-4355	273	56	expression	expression	NOUN
american_scientific_journal-4355	273	57	in	in	ADP
american_scientific_journal-4355	273	58	mediating	mediate	VERB
american_scientific_journal-4355	273	59	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	273	60	.	.	PUNCT
american_scientific_journal-4355	274	1	another	another	DET
american_scientific_journal-4355	274	2	example	example	NOUN
american_scientific_journal-4355	274	3	where	where	SCONJ
american_scientific_journal-4355	274	4	it	it	PRON
american_scientific_journal-4355	274	5	inhibits	inhibit	VERB
american_scientific_journal-4355	274	6	the	the	DET
american_scientific_journal-4355	274	7	fibrous	fibrous	ADJ
american_scientific_journal-4355	274	8	airway	airway	NOUN
american_scientific_journal-4355	274	9	obliteration	obliteration	NOUN
american_scientific_journal-4355	274	10	in	in	ADP
american_scientific_journal-4355	274	11	a	a	DET
american_scientific_journal-4355	274	12	rat	rat	NOUN
american_scientific_journal-4355	274	13	model	model	NOUN
american_scientific_journal-4355	274	14	of	of	ADP
american_scientific_journal-4355	274	15	bronchiolitis	bronchiolitis	NOUN
american_scientific_journal-4355	274	16	obliteran	obliteran	VERB
american_scientific_journal-4355	275	1	[	[	X
american_scientific_journal-4355	275	2	57	57	NUM
american_scientific_journal-4355	275	3	]	]	PUNCT
american_scientific_journal-4355	275	4	.	.	PUNCT
american_scientific_journal-4355	276	1	furthermore	furthermore	ADV
american_scientific_journal-4355	276	2	,	,	PUNCT
american_scientific_journal-4355	276	3	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	276	4	knock	knock	VERB
american_scientific_journal-4355	276	5	-	-	PUNCT
american_scientific_journal-4355	276	6	down	down	NOUN
american_scientific_journal-4355	276	7	is	be	AUX
american_scientific_journal-4355	276	8	resulted	result	VERB
american_scientific_journal-4355	276	9	in	in	ADP
american_scientific_journal-4355	276	10	decreased	decrease	VERB
american_scientific_journal-4355	276	11	growth	growth	NOUN
american_scientific_journal-4355	276	12	and	and	CCONJ
american_scientific_journal-4355	276	13	motility	motility	NOUN
american_scientific_journal-4355	276	14	of	of	ADP
american_scientific_journal-4355	276	15	human	human	ADJ
american_scientific_journal-4355	276	16	breast	breast	NOUN
american_scientific_journal-4355	276	17	cancer	cancer	NOUN
american_scientific_journal-4355	276	18	,	,	PUNCT
american_scientific_journal-4355	276	19	both	both	CCONJ
american_scientific_journal-4355	276	20	in	in	ADP
american_scientific_journal-4355	276	21	vitro	vitro	X
american_scientific_journal-4355	276	22	and	and	CCONJ
american_scientific_journal-4355	276	23	in	in	ADP
american_scientific_journal-4355	276	24	vivo	vivo	NOUN
american_scientific_journal-4355	276	25	[	[	X
american_scientific_journal-4355	276	26	58	58	NUM
american_scientific_journal-4355	276	27	]	]	PUNCT
american_scientific_journal-4355	276	28	.	.	PUNCT
american_scientific_journal-4355	277	1	this	this	DET
american_scientific_journal-4355	277	2	knock	knock	NOUN
american_scientific_journal-4355	277	3	-	-	PUNCT
american_scientific_journal-4355	277	4	down	down	NOUN
american_scientific_journal-4355	277	5	has	have	AUX
american_scientific_journal-4355	277	6	been	be	AUX
american_scientific_journal-4355	277	7	determined	determine	VERB
american_scientific_journal-4355	277	8	at	at	ADP
american_scientific_journal-4355	277	9	what	what	DET
american_scientific_journal-4355	277	10	time	time	NOUN
american_scientific_journal-4355	277	11	that	that	PRON
american_scientific_journal-4355	277	12	can	can	AUX
american_scientific_journal-4355	277	13	be	be	AUX
american_scientific_journal-4355	277	14	best	well	ADV
american_scientific_journal-4355	277	15	achieved	achieve	VERB
american_scientific_journal-4355	277	16	.	.	PUNCT
american_scientific_journal-4355	278	1	it	it	PRON
american_scientific_journal-4355	278	2	has	have	AUX
american_scientific_journal-4355	278	3	been	be	AUX
american_scientific_journal-4355	278	4	shown	show	VERB
american_scientific_journal-4355	278	5	that	that	SCONJ
american_scientific_journal-4355	278	6	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	278	7	was	be	AUX
american_scientific_journal-4355	278	8	necessary	necessary	ADJ
american_scientific_journal-4355	278	9	for	for	ADP
american_scientific_journal-4355	278	10	mediating	mediate	VERB
american_scientific_journal-4355	278	11	tgf	tgf	PROPN
american_scientific_journal-4355	278	12	-	-	PUNCT
american_scientific_journal-4355	278	13	β1	β1	NOUN
american_scientific_journal-4355	278	14	signalling	signal	VERB
american_scientific_journal-4355	278	15	through	through	ADP
american_scientific_journal-4355	278	16	smad	smad	PROPN
american_scientific_journal-4355	278	17	3	3	NUM
american_scientific_journal-4355	278	18	phosphorylation	phosphorylation	NOUN
american_scientific_journal-4355	278	19	and	and	CCONJ
american_scientific_journal-4355	278	20	that	that	SCONJ
american_scientific_journal-4355	278	21	heparan	heparan	ADJ
american_scientific_journal-4355	278	22	sulphate	sulphate	NOUN
american_scientific_journal-4355	278	23	was	be	AUX
american_scientific_journal-4355	278	24	also	also	ADV
american_scientific_journal-4355	278	25	crucial	crucial	ADJ
american_scientific_journal-4355	278	26	for	for	ADP
american_scientific_journal-4355	278	27	tgf	tgf	PROPN
american_scientific_journal-4355	278	28	-	-	PUNCT
american_scientific_journal-4355	278	29	β1	β1	PROPN
american_scientific_journal-4355	278	30	.	.	PUNCT
american_scientific_journal-4355	279	1	it	it	PRON
american_scientific_journal-4355	279	2	was	be	AUX
american_scientific_journal-4355	279	3	also	also	ADV
american_scientific_journal-4355	279	4	demonstrated	demonstrate	VERB
american_scientific_journal-4355	279	5	that	that	SCONJ
american_scientific_journal-4355	279	6	the	the	DET
american_scientific_journal-4355	279	7	tgf	tgf	PROPN
american_scientific_journal-4355	279	8	-	-	PUNCT
american_scientific_journal-4355	279	9	β1	β1	NOUN
american_scientific_journal-4355	279	10	induced	induce	VERB
american_scientific_journal-4355	279	11	change	change	NOUN
american_scientific_journal-4355	279	12	in	in	ADP
american_scientific_journal-4355	279	13	phenotype	phenotype	NOUN
american_scientific_journal-4355	279	14	depended	depend	VERB
american_scientific_journal-4355	279	15	on	on	ADP
american_scientific_journal-4355	279	16	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	279	17	expression	expression	NOUN
american_scientific_journal-4355	279	18	and	and	CCONJ
american_scientific_journal-4355	279	19	heparan	heparan	ADJ
american_scientific_journal-4355	279	20	sulphate	sulphate	NOUN
american_scientific_journal-4355	279	21	synthesis	synthesis	NOUN
american_scientific_journal-4355	279	22	.	.	PUNCT
american_scientific_journal-4355	280	1	on	on	ADP
american_scientific_journal-4355	280	2	the	the	DET
american_scientific_journal-4355	280	3	opposite	opposite	ADJ
american_scientific_journal-4355	280	4	angle	angle	NOUN
american_scientific_journal-4355	280	5	of	of	ADP
american_scientific_journal-4355	280	6	the	the	DET
american_scientific_journal-4355	280	7	scale	scale	NOUN
american_scientific_journal-4355	280	8	,	,	PUNCT
american_scientific_journal-4355	280	9	loss	loss	NOUN
american_scientific_journal-4355	280	10	of	of	ADP
american_scientific_journal-4355	280	11	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	280	12	contributes	contribute	VERB
american_scientific_journal-4355	280	13	to	to	ADP
american_scientific_journal-4355	280	14	the	the	DET
american_scientific_journal-4355	280	15	pathogenesis	pathogenesis	NOUN
american_scientific_journal-4355	280	16	of	of	ADP
american_scientific_journal-4355	280	17	gcts	gct	NOUN
american_scientific_journal-4355	280	18	(	(	PUNCT
american_scientific_journal-4355	280	19	granulosa	granulosa	NOUN
american_scientific_journal-4355	280	20	cell	cell	NOUN
american_scientific_journal-4355	280	21	tumour	tumour	NOUN
american_scientific_journal-4355	280	22	)	)	PUNCT
american_scientific_journal-4355	280	23	,	,	PUNCT
american_scientific_journal-4355	281	1	[	[	X
american_scientific_journal-4355	281	2	56	56	NUM
american_scientific_journal-4355	281	3	]	]	PUNCT
american_scientific_journal-4355	281	4	,	,	PUNCT
american_scientific_journal-4355	281	5	and	and	CCONJ
american_scientific_journal-4355	281	6	other	other	ADJ
american_scientific_journal-4355	281	7	cancers	cancer	NOUN
american_scientific_journal-4355	281	8	.	.	PUNCT
american_scientific_journal-4355	282	1	defining	define	VERB
american_scientific_journal-4355	282	2	the	the	DET
american_scientific_journal-4355	282	3	physiological	physiological	ADJ
american_scientific_journal-4355	282	4	function	function	NOUN
american_scientific_journal-4355	282	5	and	and	CCONJ
american_scientific_journal-4355	282	6	mechanism	mechanism	NOUN
american_scientific_journal-4355	282	7	of	of	ADP
american_scientific_journal-4355	282	8	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	282	9	action	action	NOUN
american_scientific_journal-4355	282	10	and	and	CCONJ
american_scientific_journal-4355	282	11	alterations	alteration	NOUN
american_scientific_journal-4355	282	12	in	in	ADP
american_scientific_journal-4355	282	13	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	282	14	activity	activity	NOUN
american_scientific_journal-4355	282	15	during	during	ADP
american_scientific_journal-4355	282	16	cancer	cancer	NOUN
american_scientific_journal-4355	282	17	progression	progression	NOUN
american_scientific_journal-4355	282	18	should	should	AUX
american_scientific_journal-4355	282	19	allow	allow	VERB
american_scientific_journal-4355	282	20	more	more	ADV
american_scientific_journal-4355	282	21	effective	effective	ADJ
american_scientific_journal-4355	282	22	targeting	targeting	NOUN
american_scientific_journal-4355	282	23	of	of	ADP
american_scientific_journal-4355	282	24	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	282	25	and	and	CCONJ
american_scientific_journal-4355	282	26	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	282	27	mediated	mediate	VERB
american_scientific_journal-4355	282	28	functions	function	NOUN
american_scientific_journal-4355	282	29	for	for	ADP
american_scientific_journal-4355	282	30	the	the	DET
american_scientific_journal-4355	282	31	diagnosis	diagnosis	NOUN
american_scientific_journal-4355	282	32	and	and	CCONJ
american_scientific_journal-4355	282	33	treatment	treatment	NOUN
american_scientific_journal-4355	282	34	of	of	ADP
american_scientific_journal-4355	282	35	human	human	ADJ
american_scientific_journal-4355	282	36	cancer	cancer	NOUN
american_scientific_journal-4355	282	37	[	[	X
american_scientific_journal-4355	282	38	59	59	NUM
american_scientific_journal-4355	282	39	]	]	PUNCT
american_scientific_journal-4355	282	40	.	.	PUNCT
american_scientific_journal-4355	283	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	283	2	might	might	AUX
american_scientific_journal-4355	283	3	play	play	VERB
american_scientific_journal-4355	283	4	a	a	DET
american_scientific_journal-4355	283	5	prominent	prominent	ADJ
american_scientific_journal-4355	283	6	role	role	NOUN
american_scientific_journal-4355	283	7	in	in	ADP
american_scientific_journal-4355	283	8	development	development	NOUN
american_scientific_journal-4355	283	9	and	and	CCONJ
american_scientific_journal-4355	283	10	progression	progression	NOUN
american_scientific_journal-4355	283	11	of	of	ADP
american_scientific_journal-4355	283	12	nsclc	nsclc	NOUN
american_scientific_journal-4355	283	13	(	(	PUNCT
american_scientific_journal-4355	283	14	non	non	ADJ
american_scientific_journal-4355	283	15	-	-	ADJ
american_scientific_journal-4355	283	16	small	small	ADJ
american_scientific_journal-4355	283	17	cell	cell	NOUN
american_scientific_journal-4355	283	18	lung	lung	NOUN
american_scientific_journal-4355	283	19	cancer	cancer	NOUN
american_scientific_journal-4355	283	20	)	)	PUNCT
american_scientific_journal-4355	283	21	and	and	CCONJ
american_scientific_journal-4355	283	22	correlate	correlate	VERB
american_scientific_journal-4355	283	23	with	with	ADP
american_scientific_journal-4355	283	24	nsclc	nsclc	NOUN
american_scientific_journal-4355	283	25	invasion	invasion	NOUN
american_scientific_journal-4355	283	26	and	and	CCONJ
american_scientific_journal-4355	283	27	migration	migration	NOUN
american_scientific_journal-4355	283	28	as	as	SCONJ
american_scientific_journal-4355	283	29	its	its	PRON
american_scientific_journal-4355	283	30	expression	expression	NOUN
american_scientific_journal-4355	283	31	observed	observe	VERB
american_scientific_journal-4355	283	32	to	to	PART
american_scientific_journal-4355	283	33	be	be	AUX
american_scientific_journal-4355	283	34	reduced	reduce	VERB
american_scientific_journal-4355	283	35	[	[	X
american_scientific_journal-4355	283	36	60	60	NUM
american_scientific_journal-4355	283	37	]	]	PUNCT
american_scientific_journal-4355	283	38	.	.	PUNCT
american_scientific_journal-4355	284	1	human	human	ADJ
american_scientific_journal-4355	284	2	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	284	3	mrna	mrna	PROPN
american_scientific_journal-4355	284	4	is	be	AUX
american_scientific_journal-4355	284	5	negatively	negatively	ADV
american_scientific_journal-4355	284	6	regulated	regulate	VERB
american_scientific_journal-4355	284	7	by	by	ADP
american_scientific_journal-4355	284	8	tgf	tgf	PROPN
american_scientific_journal-4355	284	9	-	-	PUNCT
american_scientific_journal-4355	284	10	β1	β1	PROPN
american_scientific_journal-4355	284	11	in	in	ADP
american_scientific_journal-4355	284	12	ovarian	ovarian	ADJ
american_scientific_journal-4355	284	13	and	and	CCONJ
american_scientific_journal-4355	284	14	breast	breast	NOUN
american_scientific_journal-4355	284	15	cancer	cancer	NOUN
american_scientific_journal-4355	284	16	cells	cell	NOUN
american_scientific_journal-4355	284	17	.	.	PUNCT
american_scientific_journal-4355	285	1	this	this	DET
american_scientific_journal-4355	285	2	regulation	regulation	NOUN
american_scientific_journal-4355	285	3	is	be	AUX
american_scientific_journal-4355	285	4	dependent	dependent	ADJ
american_scientific_journal-4355	285	5	on	on	ADP
american_scientific_journal-4355	285	6	tβri	tβri	NOUN
american_scientific_journal-4355	285	7	/	/	SYM
american_scientific_journal-4355	285	8	alk5(alk5	alk5(alk5	NOUN
american_scientific_journal-4355	285	9	=	=	SYM
american_scientific_journal-4355	285	10	tgf	tgf	PROPN
american_scientific_journal-4355	285	11	-	-	PUNCT
american_scientific_journal-4355	285	12	β	β	PROPN
american_scientific_journal-4355	285	13	receptor	receptor	NOUN
american_scientific_journal-4355	285	14	gene	gene	NOUN
american_scientific_journal-4355	285	15	)	)	PUNCT
american_scientific_journal-4355	285	16	and	and	CCONJ
american_scientific_journal-4355	285	17	occurs	occur	VERB
american_scientific_journal-4355	285	18	at	at	ADP
american_scientific_journal-4355	285	19	the	the	DET
american_scientific_journal-4355	285	20	transcriptional	transcriptional	ADJ
american_scientific_journal-4355	285	21	level	level	NOUN
american_scientific_journal-4355	285	22	on	on	ADP
american_scientific_journal-4355	285	23	the	the	DET
american_scientific_journal-4355	285	24	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	285	25	gene	gene	NOUN
american_scientific_journal-4355	286	1	[	[	X
american_scientific_journal-4355	286	2	58	58	NUM
american_scientific_journal-4355	286	3	]	]	PUNCT
american_scientific_journal-4355	286	4	.	.	PUNCT
american_scientific_journal-4355	287	1	loss	loss	NOUN
american_scientific_journal-4355	287	2	of	of	ADP
american_scientific_journal-4355	287	3	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	287	4	expression	expression	NOUN
american_scientific_journal-4355	287	5	can	can	AUX
american_scientific_journal-4355	287	6	cause	cause	VERB
american_scientific_journal-4355	287	7	ovarian	ovarian	ADJ
american_scientific_journal-4355	287	8	and	and	CCONJ
american_scientific_journal-4355	287	9	other	other	ADJ
american_scientific_journal-4355	287	10	cancers	cancer	NOUN
american_scientific_journal-4355	287	11	,	,	PUNCT
american_scientific_journal-4355	287	12	this	this	PRON
american_scientific_journal-4355	287	13	seems	seem	VERB
american_scientific_journal-4355	287	14	to	to	PART
american_scientific_journal-4355	287	15	be	be	AUX
american_scientific_journal-4355	287	16	due	due	ADJ
american_scientific_journal-4355	287	17	,	,	PUNCT
american_scientific_journal-4355	287	18	at	at	ADP
american_scientific_journal-4355	287	19	least	least	ADJ
american_scientific_journal-4355	287	20	in	in	ADP
american_scientific_journal-4355	287	21	part	part	NOUN
american_scientific_journal-4355	287	22	,	,	PUNCT
american_scientific_journal-4355	287	23	to	to	ADP
american_scientific_journal-4355	287	24	genetic	genetic	ADJ
american_scientific_journal-4355	287	25	silencing	silencing	NOUN
american_scientific_journal-4355	287	26	[	[	X
american_scientific_journal-4355	287	27	59	59	NUM
american_scientific_journal-4355	287	28	]	]	PUNCT
american_scientific_journal-4355	287	29	.	.	PUNCT
american_scientific_journal-4355	288	1	furthermore	furthermore	ADV
american_scientific_journal-4355	288	2	,	,	PUNCT
american_scientific_journal-4355	288	3	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	288	4	expression	expression	NOUN
american_scientific_journal-4355	288	5	is	be	AUX
american_scientific_journal-4355	288	6	frequently	frequently	ADV
american_scientific_journal-4355	288	7	decreased	decrease	VERB
american_scientific_journal-4355	288	8	or	or	CCONJ
american_scientific_journal-4355	288	9	lost	lose	VERB
american_scientific_journal-4355	288	10	in	in	ADP
american_scientific_journal-4355	288	11	human	human	ADJ
american_scientific_journal-4355	288	12	cancers	cancer	NOUN
american_scientific_journal-4355	288	13	(	(	PUNCT
american_scientific_journal-4355	288	14	i.e.	i.e.	X
american_scientific_journal-4355	288	15	65	65	NUM
american_scientific_journal-4355	288	16	%	%	NOUN
american_scientific_journal-4355	288	17	of	of	ADP
american_scientific_journal-4355	288	18	breast	breast	NOUN
american_scientific_journal-4355	288	19	cancers	cancer	NOUN
american_scientific_journal-4355	288	20	and	and	CCONJ
american_scientific_journal-4355	288	21	60	60	NUM
american_scientific_journal-4355	288	22	%	%	NOUN
american_scientific_journal-4355	288	23	of	of	ADP
american_scientific_journal-4355	288	24	prostate	prostate	NOUN
american_scientific_journal-4355	288	25	cancers	cancer	NOUN
american_scientific_journal-4355	288	26	)	)	PUNCT
american_scientific_journal-4355	288	27	.	.	PUNCT
american_scientific_journal-4355	289	1	an	an	DET
american_scientific_journal-4355	289	2	oncogenic	oncogenic	ADJ
american_scientific_journal-4355	289	3	role	role	NOUN
american_scientific_journal-4355	289	4	for	for	ADP
american_scientific_journal-4355	289	5	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	289	6	in	in	ADP
american_scientific_journal-4355	289	7	human	human	ADJ
american_scientific_journal-4355	289	8	breast	breast	NOUN
american_scientific_journal-4355	289	9	cancer	cancer	NOUN
american_scientific_journal-4355	289	10	cells	cell	NOUN
american_scientific_journal-4355	289	11	and	and	CCONJ
american_scientific_journal-4355	289	12	mouse	mouse	NOUN
american_scientific_journal-4355	289	13	mammary	mammary	ADJ
american_scientific_journal-4355	289	14	tumour	tumour	NOUN
american_scientific_journal-4355	289	15	cells	cell	NOUN
american_scientific_journal-4355	289	16	has	have	AUX
american_scientific_journal-4355	289	17	been	be	AUX
american_scientific_journal-4355	289	18	shown	show	VERB
american_scientific_journal-4355	289	19	by	by	ADP
american_scientific_journal-4355	289	20	knock	knock	NOUN
american_scientific_journal-4355	289	21	-	-	PUNCT
american_scientific_journal-4355	289	22	down	down	NOUN
american_scientific_journal-4355	289	23	of	of	ADP
american_scientific_journal-4355	289	24	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	289	25	in	in	ADP
american_scientific_journal-4355	289	26	these	these	DET
american_scientific_journal-4355	289	27	cells	cell	NOUN
american_scientific_journal-4355	289	28	and	and	CCONJ
american_scientific_journal-4355	289	29	it	it	PRON
american_scientific_journal-4355	289	30	resulted	result	VERB
american_scientific_journal-4355	289	31	in	in	ADP
american_scientific_journal-4355	289	32	decreased	decrease	VERB
american_scientific_journal-4355	289	33	growth	growth	NOUN
american_scientific_journal-4355	289	34	and	and	CCONJ
american_scientific_journal-4355	289	35	motility	motility	NOUN
american_scientific_journal-4355	289	36	,	,	PUNCT
american_scientific_journal-4355	289	37	both	both	CCONJ
american_scientific_journal-4355	289	38	in	in	ADP
american_scientific_journal-4355	289	39	vitro	vitro	X
american_scientific_journal-4355	289	40	and	and	CCONJ
american_scientific_journal-4355	289	41	in	in	ADP
american_scientific_journal-4355	289	42	vivo	vivo	NOUN
american_scientific_journal-4355	289	43	[	[	X
american_scientific_journal-4355	289	44	61	61	NUM
american_scientific_journal-4355	289	45	]	]	PUNCT
american_scientific_journal-4355	289	46	.	.	PUNCT
american_scientific_journal-4355	290	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	290	2	suppresses	suppress	VERB
american_scientific_journal-4355	290	3	cancer	cancer	NOUN
american_scientific_journal-4355	290	4	progression	progression	NOUN
american_scientific_journal-4355	290	5	,	,	PUNCT
american_scientific_journal-4355	290	6	in	in	ADP
american_scientific_journal-4355	290	7	part	part	NOUN
american_scientific_journal-4355	290	8	,	,	PUNCT
american_scientific_journal-4355	290	9	by	by	ADP
american_scientific_journal-4355	290	10	reducing	reduce	VERB
american_scientific_journal-4355	290	11	cancer	cancer	NOUN
american_scientific_journal-4355	290	12	cell	cell	NOUN
american_scientific_journal-4355	290	13	motility	motility	NOUN
american_scientific_journal-4355	290	14	,	,	PUNCT
american_scientific_journal-4355	290	15	this	this	DET
american_scientific_journal-4355	290	16	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	290	17	function	function	NOUN
american_scientific_journal-4355	290	18	is	be	AUX
american_scientific_journal-4355	290	19	independent	independent	ADJ
american_scientific_journal-4355	290	20	of	of	ADP
american_scientific_journal-4355	290	21	its	its	PRON
american_scientific_journal-4355	290	22	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	290	23	signalling	signal	VERB
american_scientific_journal-4355	290	24	role	role	NOUN
american_scientific_journal-4355	290	25	,	,	PUNCT
american_scientific_journal-4355	290	26	but	but	CCONJ
american_scientific_journal-4355	290	27	with	with	ADP
american_scientific_journal-4355	290	28	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	290	29	activating	activate	VERB
american_scientific_journal-4355	290	30	cdc42	cdc42	PROPN
american_scientific_journal-4355	290	31	via	via	ADP
american_scientific_journal-4355	290	32	its	its	PRON
american_scientific_journal-4355	290	33	interaction	interaction	NOUN
american_scientific_journal-4355	290	34	with	with	ADP
american_scientific_journal-4355	290	35	the	the	DET
american_scientific_journal-4355	290	36	scaffolding	scaffolding	NOUN
american_scientific_journal-4355	290	37	protein	protein	NOUN
american_scientific_journal-4355	290	38	beta	beta	NOUN
american_scientific_journal-4355	290	39	-	-	PUNCT
american_scientific_journal-4355	290	40	arrestin	arrestin	NOUN
american_scientific_journal-4355	290	41	2	2	NUM
american_scientific_journal-4355	290	42	to	to	PART
american_scientific_journal-4355	290	43	re	re	VERB
american_scientific_journal-4355	290	44	-	-	VERB
american_scientific_journal-4355	290	45	organize	organize	VERB
american_scientific_journal-4355	290	46	the	the	DET
american_scientific_journal-4355	290	47	actin	actin	NOUN
american_scientific_journal-4355	290	48	cytoskeleton	cytoskeleton	PROPN
american_scientific_journal-4355	290	49	,	,	PUNCT
american_scientific_journal-4355	290	50	reduce	reduce	VERB
american_scientific_journal-4355	290	51	directional	directional	ADJ
american_scientific_journal-4355	290	52	persistence	persistence	NOUN
american_scientific_journal-4355	290	53	and	and	CCONJ
american_scientific_journal-4355	290	54	prevent	prevent	VERB
american_scientific_journal-4355	290	55	random	random	ADJ
american_scientific_journal-4355	290	56	migration	migration	NOUN
american_scientific_journal-4355	290	57	in	in	ADP
american_scientific_journal-4355	290	58	both	both	CCONJ
american_scientific_journal-4355	290	59	epithelial	epithelial	ADJ
american_scientific_journal-4355	290	60	-	-	PUNCT
american_scientific_journal-4355	290	61	derived	derive	VERB
american_scientific_journal-4355	290	62	cancer	cancer	NOUN
american_scientific_journal-4355	290	63	cells	cell	NOUN
american_scientific_journal-4355	290	64	and	and	CCONJ
american_scientific_journal-4355	290	65	normal	normal	ADJ
american_scientific_journal-4355	290	66	epithelial	epithelial	ADJ
american_scientific_journal-4355	290	67	cells	cell	NOUN
american_scientific_journal-4355	290	68	[	[	X
american_scientific_journal-4355	290	69	62	62	NUM
american_scientific_journal-4355	290	70	]	]	PUNCT
american_scientific_journal-4355	290	71	.	.	PUNCT
american_scientific_journal-4355	291	1	decreased	decrease	VERB
american_scientific_journal-4355	291	2	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	291	3	expression	expression	NOUN
american_scientific_journal-4355	291	4	could	could	AUX
american_scientific_journal-4355	291	5	be	be	AUX
american_scientific_journal-4355	291	6	one	one	NUM
american_scientific_journal-4355	291	7	of	of	ADP
american_scientific_journal-4355	291	8	the	the	DET
american_scientific_journal-4355	291	9	most	most	ADV
american_scientific_journal-4355	291	10	common	common	ADJ
american_scientific_journal-4355	291	11	mechanisms	mechanism	NOUN
american_scientific_journal-4355	291	12	for	for	ADP
american_scientific_journal-4355	291	13	tgfβ	tgfβ	ADJ
american_scientific_journal-4355	291	14	resistance	resistance	NOUN
american_scientific_journal-4355	291	15	in	in	ADP
american_scientific_journal-4355	291	16	human	human	ADJ
american_scientific_journal-4355	291	17	cancers	cancer	NOUN
american_scientific_journal-4355	291	18	.	.	PUNCT
american_scientific_journal-4355	292	1	importantly	importantly	ADV
american_scientific_journal-4355	292	2	,	,	PUNCT
american_scientific_journal-4355	292	3	increasing	increase	VERB
american_scientific_journal-4355	292	4	or	or	CCONJ
american_scientific_journal-4355	292	5	restoring	restore	VERB
american_scientific_journal-4355	292	6	expression	expression	NOUN
american_scientific_journal-4355	292	7	of	of	ADP
american_scientific_journal-4355	292	8	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	292	9	in	in	ADP
american_scientific_journal-4355	292	10	these	these	DET
american_scientific_journal-4355	292	11	cancer	cancer	NOUN
american_scientific_journal-4355	292	12	models	model	NOUN
american_scientific_journal-4355	292	13	decreases	decrease	VERB
american_scientific_journal-4355	292	14	cancer	cancer	NOUN
american_scientific_journal-4355	292	15	cell	cell	NOUN
american_scientific_journal-4355	292	16	motility	motility	NOUN
american_scientific_journal-4355	292	17	and	and	CCONJ
american_scientific_journal-4355	292	18	invasion	invasion	NOUN
american_scientific_journal-4355	292	19	in	in	ADP
american_scientific_journal-4355	292	20	vitro	vitro	X
american_scientific_journal-4355	292	21	and	and	CCONJ
american_scientific_journal-4355	292	22	angiogenesis	angiogenesis	NOUN
american_scientific_journal-4355	292	23	,	,	PUNCT
american_scientific_journal-4355	292	24	invasion	invasion	NOUN
american_scientific_journal-4355	292	25	,	,	PUNCT
american_scientific_journal-4355	292	26	and	and	CCONJ
american_scientific_journal-4355	292	27	metastasis	metastasis	NOUN
american_scientific_journal-4355	292	28	in	in	ADP
american_scientific_journal-4355	292	29	vivo	vivo	NOUN
american_scientific_journal-4355	292	30	[	[	X
american_scientific_journal-4355	292	31	63	63	NUM
american_scientific_journal-4355	292	32	]	]	PUNCT
american_scientific_journal-4355	292	33	.	.	PUNCT
american_scientific_journal-4355	293	1	on	on	ADP
american_scientific_journal-4355	293	2	the	the	DET
american_scientific_journal-4355	293	3	other	other	ADJ
american_scientific_journal-4355	293	4	hand	hand	NOUN
american_scientific_journal-4355	293	5	,	,	PUNCT
american_scientific_journal-4355	293	6	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	293	7	,	,	PUNCT
american_scientific_journal-4355	293	8	is	be	AUX
american_scientific_journal-4355	293	9	a	a	DET
american_scientific_journal-4355	293	10	widely	widely	ADV
american_scientific_journal-4355	293	11	expressed	express	VERB
american_scientific_journal-4355	293	12	heparan	heparan	ADJ
american_scientific_journal-4355	293	13	and	and	CCONJ
american_scientific_journal-4355	293	14	chondroitin	chondroitin	NOUN
american_scientific_journal-4355	293	15	sulfate	sulfate	NOUN
american_scientific_journal-4355	293	16	proteoglycan	proteoglycan	NOUN
american_scientific_journal-4355	293	17	that	that	PRON
american_scientific_journal-4355	293	18	binds	bind	VERB
american_scientific_journal-4355	293	19	tgf	tgf	PROPN
american_scientific_journal-4355	293	20	-	-	PUNCT
american_scientific_journal-4355	293	21	β	β	PROPN
american_scientific_journal-4355	293	22	with	with	ADP
american_scientific_journal-4355	293	23	high	high	ADJ
american_scientific_journal-4355	293	24	affinity	affinity	NOUN
american_scientific_journal-4355	293	25	through	through	ADP
american_scientific_journal-4355	293	26	its	its	PRON
american_scientific_journal-4355	293	27	protein	protein	NOUN
american_scientific_journal-4355	293	28	core	core	NOUN
american_scientific_journal-4355	293	29	.	.	PUNCT
american_scientific_journal-4355	294	1	changing	change	VERB
american_scientific_journal-4355	294	2	glycoslation	glycoslation	NOUN
american_scientific_journal-4355	294	3	of	of	ADP
american_scientific_journal-4355	294	4	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	294	5	can	can	AUX
american_scientific_journal-4355	294	6	be	be	AUX
american_scientific_journal-4355	294	7	achieved	achieve	VERB
american_scientific_journal-4355	294	8	by	by	ADP
american_scientific_journal-4355	294	9	p	p	NOUN
american_scientific_journal-4355	294	10	-	-	PUNCT
american_scientific_journal-4355	294	11	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	294	12	-	-	PUNCT
american_scientific_journal-4355	294	13	β	β	NOUN
american_scientific_journal-4355	294	14	-	-	PUNCT
american_scientific_journal-4355	294	15	d	d	NOUN
american_scientific_journal-4355	294	16	-	-	PUNCT
american_scientific_journal-4355	294	17	xylopyrinoside	xylopyrinoside	ADJ
american_scientific_journal-4355	294	18	treatment	treatment	NOUN
american_scientific_journal-4355	294	19	.	.	PUNCT
american_scientific_journal-4355	295	1	it	it	PRON
american_scientific_journal-4355	295	2	does	do	AUX
american_scientific_journal-4355	295	3	not	not	PART
american_scientific_journal-4355	295	4	affect	affect	VERB
american_scientific_journal-4355	295	5	the	the	DET
american_scientific_journal-4355	295	6	protein	protein	NOUN
american_scientific_journal-4355	295	7	levels	level	NOUN
american_scientific_journal-4355	295	8	of	of	ADP
american_scientific_journal-4355	295	9	tβr	tβr	PROPN
american_scientific_journal-4355	295	10	-	-	PUNCT
american_scientific_journal-4355	295	11	i	i	PRON
american_scientific_journal-4355	295	12	binding	bind	VERB
american_scientific_journal-4355	295	13	tβr	tβr	PROPN
american_scientific_journal-4355	295	14	-	-	PUNCT
american_scientific_journal-4355	295	15	ii	ii	NOUN
american_scientific_journal-4355	295	16	in	in	ADP
american_scientific_journal-4355	295	17	mv1lu	mv1lu	PROPN
american_scientific_journal-4355	295	18	cells	cell	NOUN
american_scientific_journal-4355	295	19	by	by	ADP
american_scientific_journal-4355	295	20	western	western	ADJ
american_scientific_journal-4355	295	21	blot	blot	NOUN
american_scientific_journal-4355	295	22	analysis	analysis	NOUN
american_scientific_journal-4355	295	23	.	.	PUNCT
american_scientific_journal-4355	296	1	heparan	heparan	ADJ
american_scientific_journal-4355	296	2	sulphate	sulphate	NOUN
american_scientific_journal-4355	296	3	however	however	ADV
american_scientific_journal-4355	296	4	negatively	negatively	ADV
american_scientific_journal-4355	296	5	modulates	modulate	VERB
american_scientific_journal-4355	296	6	tgf	tgf	PROPN
american_scientific_journal-4355	296	7	-	-	PUNCT
american_scientific_journal-4355	296	8	β	β	NOUN
american_scientific_journal-4355	296	9	by	by	ADP
american_scientific_journal-4355	296	10	decreasing	decrease	VERB
american_scientific_journal-4355	296	11	the	the	DET
american_scientific_journal-4355	296	12	ratio	ratio	NOUN
american_scientific_journal-4355	296	13	of	of	ADP
american_scientific_journal-4355	296	14	tgf	tgf	PROPN
american_scientific_journal-4355	296	15	-	-	PUNCT
american_scientific_journal-4355	296	16	β1	β1	PROPN
american_scientific_journal-4355	296	17	binding	bind	VERB
american_scientific_journal-4355	296	18	to	to	ADP
american_scientific_journal-4355	296	19	tβr	tβr	PROPN
american_scientific_journal-4355	296	20	-	-	PUNCT
american_scientific_journal-4355	296	21	ii	ii	PROPN
american_scientific_journal-4355	296	22	and	and	CCONJ
american_scientific_journal-4355	296	23	tβr	tβr	PROPN
american_scientific_journal-4355	296	24	-	-	PUNCT
american_scientific_journal-4355	296	25	i	i	PRON
american_scientific_journal-4355	297	1	[	[	X
american_scientific_journal-4355	297	2	64	64	NUM
american_scientific_journal-4355	297	3	]	]	PUNCT
american_scientific_journal-4355	297	4	.	.	PUNCT
american_scientific_journal-4355	298	1	in	in	ADP
american_scientific_journal-4355	298	2	hk2	hk2	PROPN
american_scientific_journal-4355	298	3	cells	cell	NOUN
american_scientific_journal-4355	298	4	,	,	PUNCT
american_scientific_journal-4355	298	5	the	the	DET
american_scientific_journal-4355	298	6	luciferase	luciferase	ADJ
american_scientific_journal-4355	298	7	reporter	reporter	NOUN
american_scientific_journal-4355	298	8	assay	assay	VERB
american_scientific_journal-4355	298	9	,	,	PUNCT
american_scientific_journal-4355	298	10	revealed	reveal	VERB
american_scientific_journal-4355	298	11	that	that	SCONJ
american_scientific_journal-4355	298	12	p	p	NOUN
american_scientific_journal-4355	298	13	-	-	PUNCT
american_scientific_journal-4355	298	14	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	298	15	-	-	PUNCT
american_scientific_journal-4355	298	16	β	β	NOUN
american_scientific_journal-4355	298	17	-	-	PUNCT
american_scientific_journal-4355	298	18	d	d	NOUN
american_scientific_journal-4355	298	19	-	-	PUNCT
american_scientific_journal-4355	298	20	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	298	21	brought	bring	VERB
american_scientific_journal-4355	298	22	up	up	ADP
american_scientific_journal-4355	298	23	tgf	tgf	PROPN
american_scientific_journal-4355	298	24	-	-	PUNCT
american_scientific_journal-4355	298	25	β	β	X
american_scientific_journal-4355	298	26	induced	induce	VERB
american_scientific_journal-4355	298	27	luminescence	luminescence	NOUN
american_scientific_journal-4355	298	28	and	and	CCONJ
american_scientific_journal-4355	298	29	led	lead	VERB
american_scientific_journal-4355	298	30	to	to	ADP
american_scientific_journal-4355	298	31	tgf	tgf	PROPN
american_scientific_journal-4355	298	32	-	-	PUNCT
american_scientific_journal-4355	298	33	β	β	NOUN
american_scientific_journal-4355	298	34	up	up	ADP
american_scientific_journal-4355	298	35	-	-	PUNCT
american_scientific_journal-4355	298	36	regulation	regulation	NOUN
american_scientific_journal-4355	298	37	.	.	PUNCT
american_scientific_journal-4355	299	1	this	this	PRON
american_scientific_journal-4355	299	2	implies	imply	VERB
american_scientific_journal-4355	299	3	that	that	SCONJ
american_scientific_journal-4355	299	4	inhibition	inhibition	NOUN
american_scientific_journal-4355	299	5	of	of	ADP
american_scientific_journal-4355	299	6	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	299	7	heparan	heparan	ADJ
american_scientific_journal-4355	299	8	sulphate	sulphate	NOUN
american_scientific_journal-4355	299	9	by	by	ADP
american_scientific_journal-4355	299	10	p	p	NOUN
american_scientific_journal-4355	299	11	-	-	PUNCT
american_scientific_journal-4355	299	12	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	299	13	-	-	PUNCT
american_scientific_journal-4355	299	14	β	β	NOUN
american_scientific_journal-4355	299	15	-	-	ADJ
american_scientific_journal-4355	299	16	d	d	NOUN
american_scientific_journal-4355	299	17	-	-	PUNCT
american_scientific_journal-4355	299	18	xylopyranoside	xylopyranoside	NOUN
american_scientific_journal-4355	299	19	affects	affect	VERB
american_scientific_journal-4355	299	20	tgf	tgf	PROPN
american_scientific_journal-4355	299	21	-	-	PUNCT
american_scientific_journal-4355	299	22	β	β	NOUN
american_scientific_journal-4355	299	23	signalling	signalling	NOUN
american_scientific_journal-4355	299	24	.	.	PUNCT
american_scientific_journal-4355	300	1	all	all	PRON
american_scientific_journal-4355	300	2	of	of	ADP
american_scientific_journal-4355	300	3	these	these	PRON
american_scientific_journal-4355	300	4	affect	affect	VERB
american_scientific_journal-4355	300	5	the	the	DET
american_scientific_journal-4355	300	6	tgf	tgf	PROPN
american_scientific_journal-4355	300	7	-	-	PUNCT
american_scientific_journal-4355	300	8	β	β	PROPN
american_scientific_journal-4355	300	9	signalling	signal	VERB
american_scientific_journal-4355	300	10	function	function	NOUN
american_scientific_journal-4355	300	11	of	of	ADP
american_scientific_journal-4355	300	12	hk2	hk2	PROPN
american_scientific_journal-4355	300	13	cells	cell	NOUN
american_scientific_journal-4355	300	14	of	of	ADP
american_scientific_journal-4355	300	15	the	the	DET
american_scientific_journal-4355	300	16	kidney	kidney	NOUN
american_scientific_journal-4355	300	17	in	in	ADP
american_scientific_journal-4355	300	18	terms	term	NOUN
american_scientific_journal-4355	300	19	of	of	ADP
american_scientific_journal-4355	300	20	physical	physical	ADJ
american_scientific_journal-4355	300	21	and	and	CCONJ
american_scientific_journal-4355	300	22	biochemical	biochemical	ADJ
american_scientific_journal-4355	300	23	function	function	NOUN
american_scientific_journal-4355	300	24	as	as	ADP
american_scientific_journal-4355	300	25	tgf	tgf	PROPN
american_scientific_journal-4355	300	26	-	-	PUNCT
american_scientific_journal-4355	300	27	β	β	NOUN
american_scientific_journal-4355	300	28	protein	protein	NOUN
american_scientific_journal-4355	300	29	expression	expression	NOUN
american_scientific_journal-4355	300	30	of	of	ADP
american_scientific_journal-4355	300	31	its	its	PRON
american_scientific_journal-4355	300	32	signalling	signalling	NOUN
american_scientific_journal-4355	300	33	has	have	AUX
american_scientific_journal-4355	300	34	already	already	ADV
american_scientific_journal-4355	300	35	been	be	AUX
american_scientific_journal-4355	300	36	changed	change	VERB
american_scientific_journal-4355	300	37	,	,	PUNCT
american_scientific_journal-4355	300	38	and	and	CCONJ
american_scientific_journal-4355	300	39	this	this	PRON
american_scientific_journal-4355	300	40	shows	show	VERB
american_scientific_journal-4355	300	41	the	the	DET
american_scientific_journal-4355	300	42	link	link	NOUN
american_scientific_journal-4355	300	43	between	between	ADP
american_scientific_journal-4355	300	44	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	300	45	and	and	CCONJ
american_scientific_journal-4355	300	46	tgf	tgf	PROPN
american_scientific_journal-4355	300	47	-	-	PUNCT
american_scientific_journal-4355	300	48	β	β	NOUN
american_scientific_journal-4355	300	49	.	.	PUNCT
american_scientific_journal-4355	301	1	although	although	SCONJ
american_scientific_journal-4355	301	2	normally	normally	ADV
american_scientific_journal-4355	301	3	membrane	membrane	NOUN
american_scientific_journal-4355	301	4	anchored	anchor	VERB
american_scientific_journal-4355	301	5	,	,	PUNCT
american_scientific_journal-4355	301	6	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	301	7	can	can	AUX
american_scientific_journal-4355	301	8	undergo	undergo	VERB
american_scientific_journal-4355	301	9	proteolytic	proteolytic	ADJ
american_scientific_journal-4355	301	10	processing	processing	NOUN
american_scientific_journal-4355	301	11	in	in	ADP
american_scientific_journal-4355	301	12	vivo	vivo	NOUN
american_scientific_journal-4355	301	13	resulting	result	VERB
american_scientific_journal-4355	301	14	in	in	ADP
american_scientific_journal-4355	301	15	the	the	DET
american_scientific_journal-4355	301	16	secretion	secretion	NOUN
american_scientific_journal-4355	301	17	of	of	ADP
american_scientific_journal-4355	301	18	a	a	DET
american_scientific_journal-4355	301	19	soluble	soluble	ADJ
american_scientific_journal-4355	301	20	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	301	21	.	.	PUNCT
american_scientific_journal-4355	302	1	this	this	DET
american_scientific_journal-4355	302	2	ectodomain	ectodomain	NOUN
american_scientific_journal-4355	302	3	can	can	AUX
american_scientific_journal-4355	302	4	both	both	CCONJ
american_scientific_journal-4355	302	5	enhance	enhance	VERB
american_scientific_journal-4355	302	6	and	and	CCONJ
american_scientific_journal-4355	302	7	inhibit	inhibit	VERB
american_scientific_journal-4355	302	8	signalling	signal	VERB
american_scientific_journal-4355	302	9	depending	depend	VERB
american_scientific_journal-4355	302	10	on	on	ADP
american_scientific_journal-4355	302	11	the	the	DET
american_scientific_journal-4355	302	12	concentration	concentration	NOUN
american_scientific_journal-4355	302	13	of	of	ADP
american_scientific_journal-4355	302	14	tgf	tgf	PROPN
american_scientific_journal-4355	302	15	-	-	PUNCT
american_scientific_journal-4355	302	16	β1	β1	PROPN
american_scientific_journal-4355	302	17	present	present	NOUN
american_scientific_journal-4355	302	18	,	,	PUNCT
american_scientific_journal-4355	302	19	although	although	SCONJ
american_scientific_journal-4355	302	20	in	in	ADP
american_scientific_journal-4355	302	21	most	most	ADJ
american_scientific_journal-4355	302	22	circumstances	circumstance	NOUN
american_scientific_journal-4355	302	23	it	it	PRON
american_scientific_journal-4355	302	24	is	be	AUX
american_scientific_journal-4355	302	25	believed	believe	VERB
american_scientific_journal-4355	302	26	to	to	PART
american_scientific_journal-4355	302	27	bind	bind	VERB
american_scientific_journal-4355	302	28	and	and	CCONJ
american_scientific_journal-4355	302	29	sequester	sequester	NOUN
american_scientific_journal-4355	302	30	tgf	tgf	PROPN
american_scientific_journal-4355	302	31	-	-	PUNCT
american_scientific_journal-4355	302	32	β	β	PROPN
american_scientific_journal-4355	302	33	,	,	PUNCT
american_scientific_journal-4355	302	34	functioning	function	VERB
american_scientific_journal-4355	302	35	as	as	ADP
american_scientific_journal-4355	302	36	a	a	DET
american_scientific_journal-4355	302	37	receptor	receptor	NOUN
american_scientific_journal-4355	302	38	antagonist	antagonist	NOUN
american_scientific_journal-4355	302	39	.	.	PUNCT
american_scientific_journal-4355	303	1	in	in	ADP
american_scientific_journal-4355	303	2	the	the	DET
american_scientific_journal-4355	303	3	kidney	kidney	NOUN
american_scientific_journal-4355	303	4	,	,	PUNCT
american_scientific_journal-4355	303	5	these	these	DET
american_scientific_journal-4355	303	6	effects	effect	NOUN
american_scientific_journal-4355	303	7	have	have	AUX
american_scientific_journal-4355	303	8	reduced	reduce	VERB
american_scientific_journal-4355	303	9	renal	renal	ADJ
american_scientific_journal-4355	303	10	damage	damage	NOUN
american_scientific_journal-4355	303	11	progression	progression	NOUN
american_scientific_journal-4355	303	12	.	.	PUNCT
american_scientific_journal-4355	304	1	this	this	PRON
american_scientific_journal-4355	304	2	emphasises	emphasise	VERB
american_scientific_journal-4355	304	3	that	that	SCONJ
american_scientific_journal-4355	304	4	the	the	DET
american_scientific_journal-4355	304	5	relationship	relationship	NOUN
american_scientific_journal-4355	304	6	between	between	ADP
american_scientific_journal-4355	304	7	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	304	8	and	and	CCONJ
american_scientific_journal-4355	304	9	tgf	tgf	PROPN
american_scientific_journal-4355	304	10	-	-	PUNCT
american_scientific_journal-4355	304	11	β1	β1	PROPN
american_scientific_journal-4355	304	12	signalling	signal	VERB
american_scientific_journal-4355	304	13	is	be	AUX
american_scientific_journal-4355	304	14	complicated	complicated	ADJ
american_scientific_journal-4355	304	15	because	because	SCONJ
american_scientific_journal-4355	304	16	the	the	DET
american_scientific_journal-4355	304	17	former	former	NOUN
american_scientific_journal-4355	304	18	has	have	AUX
american_scientific_journal-4355	304	19	shown	show	VERB
american_scientific_journal-4355	304	20	different	different	ADJ
american_scientific_journal-4355	304	21	regulatory	regulatory	ADJ
american_scientific_journal-4355	304	22	mechanisms	mechanism	NOUN
american_scientific_journal-4355	304	23	upon	upon	SCONJ
american_scientific_journal-4355	304	24	tgf	tgf	PROPN
american_scientific_journal-4355	304	25	-	-	PUNCT
american_scientific_journal-4355	304	26	β	β	NOUN
american_scientific_journal-4355	304	27	action	action	NOUN
american_scientific_journal-4355	304	28	.	.	PUNCT
american_scientific_journal-4355	305	1	it	it	PRON
american_scientific_journal-4355	305	2	was	be	AUX
american_scientific_journal-4355	305	3	believed	believe	VERB
american_scientific_journal-4355	305	4	that	that	SCONJ
american_scientific_journal-4355	305	5	sbg	sbg	NOUN
american_scientific_journal-4355	305	6	(	(	PUNCT
american_scientific_journal-4355	305	7	soluble	soluble	ADJ
american_scientific_journal-4355	305	8	betaglyccan	betaglyccan	NOUN
american_scientific_journal-4355	305	9	)	)	PUNCT
american_scientific_journal-4355	305	10	shall	shall	AUX
american_scientific_journal-4355	305	11	prove	prove	VERB
american_scientific_journal-4355	305	12	convenient	convenient	ADJ
american_scientific_journal-4355	305	13	for	for	ADP
american_scientific_journal-4355	305	14	long	long	ADJ
american_scientific_journal-4355	305	15	-	-	PUNCT
american_scientific_journal-4355	305	16	term	term	NOUN
american_scientific_journal-4355	305	17	treatment	treatment	NOUN
american_scientific_journal-4355	305	18	of	of	ADP
american_scientific_journal-4355	305	19	kidney	kidney	NOUN
american_scientific_journal-4355	305	20	diseases	disease	NOUN
american_scientific_journal-4355	305	21	and	and	CCONJ
american_scientific_journal-4355	305	22	other	other	ADJ
american_scientific_journal-4355	305	23	pathologies	pathology	NOUN
american_scientific_journal-4355	305	24	in	in	ADP
american_scientific_journal-4355	305	25	which	which	PRON
american_scientific_journal-4355	305	26	tgf	tgf	PROPN
american_scientific_journal-4355	305	27	-	-	PUNCT
american_scientific_journal-4355	305	28	β	β	PROPN
american_scientific_journal-4355	305	29	plays	play	VERB
american_scientific_journal-4355	305	30	a	a	DET
american_scientific_journal-4355	305	31	pathophysiological	pathophysiological	ADJ
american_scientific_journal-4355	305	32	role	role	NOUN
american_scientific_journal-4355	305	33	[	[	X
american_scientific_journal-4355	305	34	65	65	NUM
american_scientific_journal-4355	305	35	]	]	PUNCT
american_scientific_journal-4355	305	36	.	.	PUNCT
american_scientific_journal-4355	306	1	soluble	soluble	ADJ
american_scientific_journal-4355	306	2	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	306	3	,	,	PUNCT
american_scientific_journal-4355	306	4	which	which	PRON
american_scientific_journal-4355	306	5	is	be	AUX
american_scientific_journal-4355	306	6	produced	produce	VERB
american_scientific_journal-4355	306	7	by	by	ADP
american_scientific_journal-4355	306	8	the	the	DET
american_scientific_journal-4355	306	9	shedding	shedding	NOUN
american_scientific_journal-4355	306	10	of	of	ADP
american_scientific_journal-4355	306	11	the	the	DET
american_scientific_journal-4355	306	12	membrane	membrane	NOUN
american_scientific_journal-4355	306	13	-	-	PUNCT
american_scientific_journal-4355	306	14	bound	bind	VERB
american_scientific_journal-4355	306	15	receptor	receptor	NOUN
american_scientific_journal-4355	306	16	,	,	PUNCT
american_scientific_journal-4355	306	17	is	be	AUX
american_scientific_journal-4355	306	18	a	a	DET
american_scientific_journal-4355	306	19	potent	potent	ADJ
american_scientific_journal-4355	306	20	antagonist	antagonist	NOUN
american_scientific_journal-4355	306	21	of	of	ADP
american_scientific_journal-4355	306	22	tgf	tgf	PROPN
american_scientific_journal-4355	306	23	-	-	PUNCT
american_scientific_journal-4355	306	24	β	β	NOUN
american_scientific_journal-4355	306	25	.	.	PUNCT
american_scientific_journal-4355	306	26	inhibitory	inhibitory	ADJ
american_scientific_journal-4355	306	27	,	,	PUNCT
american_scientific_journal-4355	306	28	but	but	CCONJ
american_scientific_journal-4355	306	29	as	as	ADP
american_scientific_journal-4355	306	30	tumorigenesis	tumorigenesis	NOUN
american_scientific_journal-4355	306	31	progresses	progress	NOUN
american_scientific_journal-4355	306	32	,	,	PUNCT
american_scientific_journal-4355	306	33	tgf	tgf	PROPN
american_scientific_journal-4355	306	34	-	-	PUNCT
american_scientific_journal-4355	306	35	β	β	PROPN
american_scientific_journal-4355	306	36	becomes	become	VERB
american_scientific_journal-4355	306	37	prometastatic	prometastatic	ADJ
american_scientific_journal-4355	306	38	[	[	PUNCT
american_scientific_journal-4355	306	39	66	66	NUM
american_scientific_journal-4355	306	40	]	]	PUNCT
american_scientific_journal-4355	306	41	.	.	PUNCT
american_scientific_journal-4355	307	1	in	in	ADP
american_scientific_journal-4355	307	2	this	this	DET
american_scientific_journal-4355	307	3	thesis	thesis	NOUN
american_scientific_journal-4355	307	4	,	,	PUNCT
american_scientific_journal-4355	307	5	experiments	experiment	NOUN
american_scientific_journal-4355	307	6	and	and	CCONJ
american_scientific_journal-4355	307	7	results	result	NOUN
american_scientific_journal-4355	307	8	of	of	ADP
american_scientific_journal-4355	307	9	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	307	10	mrna	mrna	PROPN
american_scientific_journal-4355	307	11	and	and	CCONJ
american_scientific_journal-4355	307	12	core	core	NOUN
american_scientific_journal-4355	307	13	protein	protein	NOUN
american_scientific_journal-4355	307	14	were	be	AUX
american_scientific_journal-4355	307	15	knocked	knock	VERB
american_scientific_journal-4355	307	16	-	-	PUNCT
american_scientific_journal-4355	307	17	down	down	NOUN
american_scientific_journal-4355	307	18	and	and	CCONJ
american_scientific_journal-4355	307	19	this	this	DET
american_scientific_journal-4355	307	20	alteration	alteration	NOUN
american_scientific_journal-4355	307	21	has	have	VERB
american_scientific_journal-4355	307	22	a	a	DET
american_scientific_journal-4355	307	23	role	role	NOUN
american_scientific_journal-4355	307	24	in	in	ADP
american_scientific_journal-4355	307	25	hk2	hk2	PROPN
american_scientific_journal-4355	307	26	cells	cell	NOUN
american_scientific_journal-4355	307	27	transition	transition	NOUN
american_scientific_journal-4355	307	28	or	or	CCONJ
american_scientific_journal-4355	307	29	transformation	transformation	NOUN
american_scientific_journal-4355	307	30	in	in	ADP
american_scientific_journal-4355	307	31	terms	term	NOUN
american_scientific_journal-4355	307	32	of	of	ADP
american_scientific_journal-4355	307	33	minimal	minimal	ADJ
american_scientific_journal-4355	307	34	loss	loss	NOUN
american_scientific_journal-4355	307	35	of	of	ADP
american_scientific_journal-4355	307	36	expression	expression	NOUN
american_scientific_journal-4355	307	37	of	of	ADP
american_scientific_journal-4355	307	38	the	the	DET
american_scientific_journal-4355	307	39	epithelial	epithelial	ADJ
american_scientific_journal-4355	307	40	marker	marker	NOUN
american_scientific_journal-4355	307	41	e‐cadherin	e‐cadherin	SYM
american_scientific_journal-4355	307	42	expression	expression	NOUN
american_scientific_journal-4355	307	43	changes	change	NOUN
american_scientific_journal-4355	307	44	,	,	PUNCT
american_scientific_journal-4355	307	45	and	and	CCONJ
american_scientific_journal-4355	308	1	also	also	ADV
american_scientific_journal-4355	308	2	mildly	mildly	ADV
american_scientific_journal-4355	308	3	increased	increase	VERB
american_scientific_journal-4355	308	4	cytoskeletal	cytoskeletal	ADJ
american_scientific_journal-4355	308	5	proteins	protein	NOUN
american_scientific_journal-4355	308	6	α‐sma	α‐sma	PROPN
american_scientific_journal-4355	308	7	(	(	PUNCT
american_scientific_journal-4355	308	8	signs	sign	NOUN
american_scientific_journal-4355	308	9	of	of	ADP
american_scientific_journal-4355	308	10	emt	emt	PROPN
american_scientific_journal-4355	308	11	)	)	PUNCT
american_scientific_journal-4355	308	12	.	.	PUNCT
american_scientific_journal-4355	309	1	epithelial	epithelial	ADJ
american_scientific_journal-4355	309	2	cells	cell	NOUN
american_scientific_journal-4355	309	3	are	be	AUX
american_scientific_journal-4355	309	4	typically	typically	ADV
american_scientific_journal-4355	309	5	characterized	characterize	VERB
american_scientific_journal-4355	309	6	by	by	ADP
american_scientific_journal-4355	309	7	intercellular	intercellular	ADJ
american_scientific_journal-4355	309	8	adhesion	adhesion	NOUN
american_scientific_journal-4355	309	9	complexes	complex	NOUN
american_scientific_journal-4355	309	10	in	in	ADP
american_scientific_journal-4355	309	11	their	their	PRON
american_scientific_journal-4355	309	12	lateral	lateral	ADJ
american_scientific_journal-4355	309	13	membranes	membrane	NOUN
american_scientific_journal-4355	309	14	which	which	PRON
american_scientific_journal-4355	309	15	enable	enable	VERB
american_scientific_journal-4355	309	16	them	they	PRON
american_scientific_journal-4355	309	17	to	to	PART
american_scientific_journal-4355	309	18	be	be	AUX
american_scientific_journal-4355	309	19	closely	closely	ADV
american_scientific_journal-4355	309	20	attached	attach	VERB
american_scientific_journal-4355	309	21	to	to	ADP
american_scientific_journal-4355	309	22	each	each	DET
american_scientific_journal-4355	309	23	other	other	ADJ
american_scientific_journal-4355	309	24	and	and	CCONJ
american_scientific_journal-4355	309	25	to	to	PART
american_scientific_journal-4355	309	26	form	form	VERB
american_scientific_journal-4355	309	27	cell	cell	NOUN
american_scientific_journal-4355	309	28	layers	layer	NOUN
american_scientific_journal-4355	309	29	.	.	PUNCT
american_scientific_journal-4355	310	1	they	they	PRON
american_scientific_journal-4355	310	2	display	display	VERB
american_scientific_journal-4355	310	3	an	an	DET
american_scientific_journal-4355	310	4	apico	apico	NOUN
american_scientific_journal-4355	310	5	-	-	PUNCT
american_scientific_journal-4355	310	6	basal	basal	NOUN
american_scientific_journal-4355	310	7	polarity	polarity	NOUN
american_scientific_journal-4355	310	8	,	,	PUNCT
american_scientific_journal-4355	310	9	and	and	CCONJ
american_scientific_journal-4355	310	10	are	be	AUX
american_scientific_journal-4355	310	11	separated	separate	VERB
american_scientific_journal-4355	310	12	by	by	ADP
american_scientific_journal-4355	310	13	the	the	DET
american_scientific_journal-4355	310	14	basement	basement	NOUN
american_scientific_journal-4355	310	15	membrane	membrane	NOUN
american_scientific_journal-4355	310	16	from	from	ADP
american_scientific_journal-4355	310	17	other	other	ADJ
american_scientific_journal-4355	310	18	tissues	tissue	NOUN
american_scientific_journal-4355	310	19	in	in	ADP
american_scientific_journal-4355	310	20	the	the	DET
american_scientific_journal-4355	310	21	body	body	NOUN
american_scientific_journal-4355	310	22	.	.	PUNCT
american_scientific_journal-4355	311	1	in	in	ADP
american_scientific_journal-4355	311	2	contrast	contrast	NOUN
american_scientific_journal-4355	311	3	to	to	ADP
american_scientific_journal-4355	311	4	epithelial	epithelial	ADJ
american_scientific_journal-4355	311	5	cells	cell	NOUN
american_scientific_journal-4355	311	6	,	,	PUNCT
american_scientific_journal-4355	311	7	mesenchymal	mesenchymal	ADJ
american_scientific_journal-4355	311	8	cells	cell	NOUN
american_scientific_journal-4355	311	9	are	be	AUX
american_scientific_journal-4355	311	10	capable	capable	ADJ
american_scientific_journal-4355	311	11	of	of	ADP
american_scientific_journal-4355	311	12	moving	move	VERB
american_scientific_journal-4355	311	13	individually	individually	ADV
american_scientific_journal-4355	311	14	through	through	ADP
american_scientific_journal-4355	311	15	the	the	DET
american_scientific_journal-4355	311	16	extracellular	extracellular	ADJ
american_scientific_journal-4355	311	17	matrix	matrix	NOUN
american_scientific_journal-4355	311	18	since	since	SCONJ
american_scientific_journal-4355	311	19	they	they	PRON
american_scientific_journal-4355	311	20	lack	lack	VERB
american_scientific_journal-4355	311	21	intercellular	intercellular	ADJ
american_scientific_journal-4355	311	22	junctions	junction	NOUN
american_scientific_journal-4355	311	23	,	,	PUNCT
american_scientific_journal-4355	311	24	and	and	CCONJ
american_scientific_journal-4355	311	25	do	do	AUX
american_scientific_journal-4355	311	26	not	not	PART
american_scientific_journal-4355	311	27	display	display	VERB
american_scientific_journal-4355	311	28	an	an	DET
american_scientific_journal-4355	311	29	apico‐basal	apico‐basal	NOUN
american_scientific_journal-4355	311	30	-	-	PUNCT
american_scientific_journal-4355	311	31	polarity	polarity	NOUN
american_scientific_journal-4355	311	32	[	[	X
american_scientific_journal-4355	311	33	67	67	NUM
american_scientific_journal-4355	311	34	]	]	PUNCT
american_scientific_journal-4355	311	35	.	.	PUNCT
american_scientific_journal-4355	312	1	cells	cell	NOUN
american_scientific_journal-4355	312	2	that	that	PRON
american_scientific_journal-4355	312	3	have	have	AUX
american_scientific_journal-4355	312	4	undergone	undergo	VERB
american_scientific_journal-4355	312	5	emt	emt	NOUN
american_scientific_journal-4355	312	6	reveal	reveal	NOUN
american_scientific_journal-4355	312	7	changes	change	NOUN
american_scientific_journal-4355	312	8	in	in	ADP
american_scientific_journal-4355	312	9	their	their	PRON
american_scientific_journal-4355	312	10	migratory	migratory	ADJ
american_scientific_journal-4355	312	11	capacity	capacity	NOUN
american_scientific_journal-4355	312	12	and	and	CCONJ
american_scientific_journal-4355	312	13	responses	response	NOUN
american_scientific_journal-4355	312	14	to	to	ADP
american_scientific_journal-4355	312	15	external	external	ADJ
american_scientific_journal-4355	312	16	signals	signal	NOUN
american_scientific_journal-4355	312	17	[	[	X
american_scientific_journal-4355	312	18	68	68	NUM
american_scientific_journal-4355	312	19	]	]	PUNCT
american_scientific_journal-4355	312	20	.	.	PUNCT
american_scientific_journal-4355	313	1	not	not	PART
american_scientific_journal-4355	313	2	only	only	ADV
american_scientific_journal-4355	313	3	signalling	signal	VERB
american_scientific_journal-4355	313	4	function	function	NOUN
american_scientific_journal-4355	313	5	,	,	PUNCT
american_scientific_journal-4355	313	6	but	but	CCONJ
american_scientific_journal-4355	313	7	changes	change	NOUN
american_scientific_journal-4355	313	8	of	of	ADP
american_scientific_journal-4355	313	9	function	function	NOUN
american_scientific_journal-4355	313	10	as	as	ADV
american_scientific_journal-4355	313	11	well	well	ADV
american_scientific_journal-4355	313	12	(	(	PUNCT
american_scientific_journal-4355	313	13	emt	emt	PROPN
american_scientific_journal-4355	313	14	)	)	PUNCT
american_scientific_journal-4355	313	15	as	as	SCONJ
american_scientific_journal-4355	313	16	there	there	PRON
american_scientific_journal-4355	313	17	was	be	VERB
american_scientific_journal-4355	313	18	a	a	DET
american_scientific_journal-4355	313	19	down	down	ADJ
american_scientific_journal-4355	313	20	regulation	regulation	NOUN
american_scientific_journal-4355	313	21	of	of	ADP
american_scientific_journal-4355	313	22	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	313	23	,	,	PUNCT
american_scientific_journal-4355	313	24	mild	mild	ADJ
american_scientific_journal-4355	313	25	e	e	NOUN
american_scientific_journal-4355	313	26	-	-	NOUN
american_scientific_journal-4355	313	27	cadherin	cadherin	NOUN
american_scientific_journal-4355	313	28	and	and	CCONJ
american_scientific_journal-4355	313	29	α	α	NOUN
american_scientific_journal-4355	313	30	-	-	PUNCT
american_scientific_journal-4355	313	31	sma	sma	NOUN
american_scientific_journal-4355	313	32	changes	change	NOUN
american_scientific_journal-4355	313	33	,	,	PUNCT
american_scientific_journal-4355	313	34	that	that	PRON
american_scientific_journal-4355	313	35	might	might	AUX
american_scientific_journal-4355	313	36	be	be	AUX
american_scientific_journal-4355	313	37	attributed	attribute	VERB
american_scientific_journal-4355	313	38	to	to	ADP
american_scientific_journal-4355	313	39	the	the	DET
american_scientific_journal-4355	313	40	inhibition	inhibition	NOUN
american_scientific_journal-4355	313	41	of	of	ADP
american_scientific_journal-4355	313	42	smad2	smad2	ADJ
american_scientific_journal-4355	313	43	expression	expression	NOUN
american_scientific_journal-4355	313	44	with	with	ADP
american_scientific_journal-4355	313	45	a	a	DET
american_scientific_journal-4355	313	46	failure	failure	NOUN
american_scientific_journal-4355	313	47	of	of	ADP
american_scientific_journal-4355	313	48	tgf	tgf	PROPN
american_scientific_journal-4355	313	49	-	-	PUNCT
american_scientific_journal-4355	313	50	β1	β1	PROPN
american_scientific_journal-4355	313	51	to	to	PART
american_scientific_journal-4355	313	52	increase	increase	VERB
american_scientific_journal-4355	313	53	α	α	PRON
american_scientific_journal-4355	313	54	-	-	PUNCT
american_scientific_journal-4355	313	55	sma	sma	NOUN
american_scientific_journal-4355	313	56	,	,	PUNCT
american_scientific_journal-4355	313	57	confirming	confirm	VERB
american_scientific_journal-4355	313	58	the	the	DET
american_scientific_journal-4355	313	59	involvement	involvement	NOUN
american_scientific_journal-4355	313	60	of	of	ADP
american_scientific_journal-4355	313	61	this	this	PRON
american_scientific_journal-4355	313	62	signalling	signal	VERB
american_scientific_journal-4355	313	63	in	in	ADP
american_scientific_journal-4355	313	64	phenotypic	phenotypic	ADJ
american_scientific_journal-4355	313	65	activation	activation	NOUN
american_scientific_journal-4355	313	66	[	[	X
american_scientific_journal-4355	313	67	68	68	NUM
american_scientific_journal-4355	313	68	]	]	PUNCT
american_scientific_journal-4355	313	69	.	.	PUNCT
american_scientific_journal-4355	314	1	in	in	ADP
american_scientific_journal-4355	314	2	contrast	contrast	NOUN
american_scientific_journal-4355	314	3	,	,	PUNCT
american_scientific_journal-4355	314	4	successful	successful	ADJ
american_scientific_journal-4355	314	5	knockdown	knockdown	NOUN
american_scientific_journal-4355	314	6	of	of	ADP
american_scientific_journal-4355	314	7	smad3	smad3	NOUN
american_scientific_journal-4355	314	8	using	use	VERB
american_scientific_journal-4355	314	9	sirna	sirna	PROPN
american_scientific_journal-4355	314	10	failed	fail	VERB
american_scientific_journal-4355	314	11	to	to	PART
american_scientific_journal-4355	314	12	have	have	VERB
american_scientific_journal-4355	314	13	an	an	DET
american_scientific_journal-4355	314	14	impact	impact	NOUN
american_scientific_journal-4355	314	15	on	on	ADP
american_scientific_journal-4355	314	16	tgf	tgf	PROPN
american_scientific_journal-4355	314	17	-	-	PUNCT
american_scientific_journal-4355	314	18	β1	β1	NOUN
american_scientific_journal-4355	314	19	-	-	PUNCT
american_scientific_journal-4355	314	20	mediated	mediate	VERB
american_scientific_journal-4355	314	21	phenotypic	phenotypic	ADJ
american_scientific_journal-4355	314	22	differentiation	differentiation	NOUN
american_scientific_journal-4355	314	23	[	[	X
american_scientific_journal-4355	314	24	69	69	NUM
american_scientific_journal-4355	314	25	]	]	PUNCT
american_scientific_journal-4355	314	26	.	.	PUNCT
american_scientific_journal-4355	315	1	in	in	ADP
american_scientific_journal-4355	315	2	immortalised	immortalise	VERB
american_scientific_journal-4355	315	3	hk2	hk2	NOUN
american_scientific_journal-4355	315	4	cells	cell	NOUN
american_scientific_journal-4355	315	5	,	,	PUNCT
american_scientific_journal-4355	315	6	pai-1	pai-1	NUM
american_scientific_journal-4355	315	7	expression	expression	NOUN
american_scientific_journal-4355	315	8	decreased	decrease	VERB
american_scientific_journal-4355	315	9	when	when	SCONJ
american_scientific_journal-4355	315	10	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	315	11	knocked	knock	VERB
american_scientific_journal-4355	315	12	-	-	PUNCT
american_scientific_journal-4355	315	13	down	down	ADP
american_scientific_journal-4355	315	14	and	and	CCONJ
american_scientific_journal-4355	315	15	when	when	SCONJ
american_scientific_journal-4355	315	16	tgf	tgf	PROPN
american_scientific_journal-4355	315	17	-	-	PUNCT
american_scientific_journal-4355	315	18	β	β	PROPN
american_scientific_journal-4355	315	19	was	be	AUX
american_scientific_journal-4355	315	20	applied	apply	VERB
american_scientific_journal-4355	315	21	,	,	PUNCT
american_scientific_journal-4355	315	22	and	and	CCONJ
american_scientific_journal-4355	315	23	pai-1	pai-1	NUM
american_scientific_journal-4355	315	24	expression	expression	NOUN
american_scientific_journal-4355	315	25	increased	increase	VERB
american_scientific_journal-4355	315	26	;	;	PUNCT
american_scientific_journal-4355	315	27	that	that	PRON
american_scientific_journal-4355	315	28	might	might	AUX
american_scientific_journal-4355	315	29	be	be	AUX
american_scientific_journal-4355	315	30	attributed	attribute	VERB
american_scientific_journal-4355	315	31	to	to	ADP
american_scientific_journal-4355	315	32	the	the	DET
american_scientific_journal-4355	315	33	fact	fact	NOUN
american_scientific_journal-4355	315	34	that	that	SCONJ
american_scientific_journal-4355	315	35	pai-1	pai-1	PRON
american_scientific_journal-4355	315	36	has	have	AUX
american_scientific_journal-4355	315	37	no	no	DET
american_scientific_journal-4355	315	38	relationship	relationship	NOUN
american_scientific_journal-4355	315	39	with	with	ADP
american_scientific_journal-4355	315	40	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	315	41	or	or	CCONJ
american_scientific_journal-4355	315	42	pai-1	pai-1	PUNCT
american_scientific_journal-4355	315	43	has	have	VERB
american_scientific_journal-4355	315	44	another	another	DET
american_scientific_journal-4355	315	45	pathway	pathway	NOUN
american_scientific_journal-4355	315	46	of	of	ADP
american_scientific_journal-4355	315	47	action	action	NOUN
american_scientific_journal-4355	315	48	despite	despite	SCONJ
american_scientific_journal-4355	315	49	being	be	AUX
american_scientific_journal-4355	315	50	turned	turn	VERB
american_scientific_journal-4355	315	51	up	up	ADP
american_scientific_journal-4355	315	52	by	by	ADP
american_scientific_journal-4355	315	53	tgf	tgf	PROPN
american_scientific_journal-4355	315	54	-	-	PUNCT
american_scientific_journal-4355	315	55	β	β	NOUN
american_scientific_journal-4355	315	56	.	.	PROPN
american_scientific_journal-4355	315	57	4	4	X
american_scientific_journal-4355	315	58	.	.	X
american_scientific_journal-4355	315	59	limitations	limitation	NOUN
american_scientific_journal-4355	315	60	there	there	PRON
american_scientific_journal-4355	315	61	are	be	VERB
american_scientific_journal-4355	315	62	some	some	DET
american_scientific_journal-4355	315	63	limitations	limitation	NOUN
american_scientific_journal-4355	315	64	in	in	ADP
american_scientific_journal-4355	315	65	this	this	DET
american_scientific_journal-4355	315	66	work	work	NOUN
american_scientific_journal-4355	315	67	which	which	PRON
american_scientific_journal-4355	315	68	must	must	AUX
american_scientific_journal-4355	315	69	be	be	AUX
american_scientific_journal-4355	315	70	taken	take	VERB
american_scientific_journal-4355	315	71	into	into	ADP
american_scientific_journal-4355	315	72	account	account	NOUN
american_scientific_journal-4355	315	73	:	:	PUNCT
american_scientific_journal-4355	315	74	firstly	firstly	ADV
american_scientific_journal-4355	315	75	,	,	PUNCT
american_scientific_journal-4355	315	76	p	p	NOUN
american_scientific_journal-4355	315	77	-	-	PUNCT
american_scientific_journal-4355	315	78	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	315	79	-	-	PUNCT
american_scientific_journal-4355	315	80	β	β	NOUN
american_scientific_journal-4355	315	81	-	-	PUNCT
american_scientific_journal-4355	315	82	d	d	NOUN
american_scientific_journal-4355	315	83	-	-	PUNCT
american_scientific_journal-4355	315	84	xylopyrinoside	xylopyrinoside	ADJ
american_scientific_journal-4355	315	85	analysis	analysis	NOUN
american_scientific_journal-4355	315	86	has	have	AUX
american_scientific_journal-4355	315	87	been	be	AUX
american_scientific_journal-4355	315	88	used	use	VERB
american_scientific_journal-4355	315	89	to	to	PART
american_scientific_journal-4355	315	90	suppress	suppress	VERB
american_scientific_journal-4355	315	91	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	315	92	heparan	heparan	ADJ
american_scientific_journal-4355	315	93	sulphate	sulphate	NOUN
american_scientific_journal-4355	315	94	,	,	PUNCT
american_scientific_journal-4355	315	95	and	and	CCONJ
american_scientific_journal-4355	315	96	this	this	DET
american_scientific_journal-4355	315	97	action	action	NOUN
american_scientific_journal-4355	315	98	is	be	AUX
american_scientific_journal-4355	315	99	not	not	PART
american_scientific_journal-4355	315	100	specific	specific	ADJ
american_scientific_journal-4355	315	101	for	for	ADP
american_scientific_journal-4355	315	102	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	315	103	as	as	SCONJ
american_scientific_journal-4355	315	104	it	it	PRON
american_scientific_journal-4355	315	105	might	might	AUX
american_scientific_journal-4355	315	106	inhibit	inhibit	VERB
american_scientific_journal-4355	315	107	all	all	DET
american_scientific_journal-4355	315	108	heparan	heparan	NOUN
american_scientific_journal-4355	315	109	of	of	ADP
american_scientific_journal-4355	315	110	other	other	ADJ
american_scientific_journal-4355	315	111	structures	structure	NOUN
american_scientific_journal-4355	315	112	(	(	PUNCT
american_scientific_journal-4355	315	113	off	off	ADP
american_scientific_journal-4355	315	114	target	target	NOUN
american_scientific_journal-4355	315	115	)	)	PUNCT
american_scientific_journal-4355	315	116	.	.	PUNCT
american_scientific_journal-4355	316	1	this	this	PRON
american_scientific_journal-4355	316	2	will	will	AUX
american_scientific_journal-4355	316	3	have	have	VERB
american_scientific_journal-4355	316	4	an	an	DET
american_scientific_journal-4355	316	5	impact	impact	NOUN
american_scientific_journal-4355	316	6	on	on	ADP
american_scientific_journal-4355	316	7	the	the	DET
american_scientific_journal-4355	316	8	result	result	NOUN
american_scientific_journal-4355	316	9	of	of	ADP
american_scientific_journal-4355	316	10	the	the	DET
american_scientific_journal-4355	316	11	experiment	experiment	NOUN
american_scientific_journal-4355	316	12	as	as	SCONJ
american_scientific_journal-4355	316	13	heparan	heparan	ADJ
american_scientific_journal-4355	316	14	sulphate	sulphate	NOUN
american_scientific_journal-4355	316	15	inhibition	inhibition	NOUN
american_scientific_journal-4355	316	16	might	might	AUX
american_scientific_journal-4355	316	17	be	be	AUX
american_scientific_journal-4355	316	18	incompletesecondly	incompletesecondly	ADV
american_scientific_journal-4355	316	19	,	,	PUNCT
american_scientific_journal-4355	316	20	soluble	soluble	ADJ
american_scientific_journal-4355	316	21	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	316	22	has	have	AUX
american_scientific_journal-4355	316	23	not	not	PART
american_scientific_journal-4355	316	24	been	be	AUX
american_scientific_journal-4355	316	25	studied	study	VERB
american_scientific_journal-4355	316	26	in	in	ADP
american_scientific_journal-4355	316	27	this	this	DET
american_scientific_journal-4355	316	28	work	work	NOUN
american_scientific_journal-4355	316	29	,	,	PUNCT
american_scientific_journal-4355	316	30	and	and	CCONJ
american_scientific_journal-4355	316	31	if	if	SCONJ
american_scientific_journal-4355	316	32	we	we	PRON
american_scientific_journal-4355	316	33	did	do	VERB
american_scientific_journal-4355	316	34	,	,	PUNCT
american_scientific_journal-4355	316	35	there	there	PRON
american_scientific_journal-4355	316	36	would	would	AUX
american_scientific_journal-4355	316	37	have	have	AUX
american_scientific_journal-4355	316	38	been	be	AUX
american_scientific_journal-4355	316	39	many	many	ADJ
american_scientific_journal-4355	316	40	results	result	NOUN
american_scientific_journal-4355	316	41	arising	arise	VERB
american_scientific_journal-4355	316	42	from	from	ADP
american_scientific_journal-4355	316	43	the	the	DET
american_scientific_journal-4355	316	44	association	association	NOUN
american_scientific_journal-4355	316	45	of	of	ADP
american_scientific_journal-4355	316	46	both	both	CCONJ
american_scientific_journal-4355	316	47	soluble	soluble	ADJ
american_scientific_journal-4355	316	48	as	as	ADV
american_scientific_journal-4355	316	49	well	well	ADV
american_scientific_journal-4355	316	50	as	as	ADP
american_scientific_journal-4355	316	51	membranous	membranous	ADJ
american_scientific_journal-4355	316	52	portion	portion	NOUN
american_scientific_journal-4355	316	53	of	of	ADP
american_scientific_journal-4355	316	54	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	316	55	,	,	PUNCT
american_scientific_journal-4355	316	56	both	both	PRON
american_scientific_journal-4355	316	57	of	of	ADP
american_scientific_journal-4355	316	58	which	which	PRON
american_scientific_journal-4355	316	59	could	could	AUX
american_scientific_journal-4355	316	60	have	have	AUX
american_scientific_journal-4355	316	61	resulted	result	VERB
american_scientific_journal-4355	316	62	in	in	ADP
american_scientific_journal-4355	316	63	further	further	ADJ
american_scientific_journal-4355	316	64	action	action	NOUN
american_scientific_journal-4355	316	65	on	on	ADP
american_scientific_journal-4355	316	66	tgf	tgf	PROPN
american_scientific_journal-4355	316	67	-	-	PUNCT
american_scientific_journal-4355	316	68	β	β	PROPN
american_scientific_journal-4355	316	69	,	,	PUNCT
american_scientific_journal-4355	317	1	the	the	DET
american_scientific_journal-4355	317	2	sbg	sbg	PROPN
american_scientific_journal-4355	317	3	sequester	sequester	PROPN
american_scientific_journal-4355	317	4	tgf	tgf	PROPN
american_scientific_journal-4355	317	5	-	-	PUNCT
american_scientific_journal-4355	317	6	β	β	PROPN
american_scientific_journal-4355	317	7	while	while	SCONJ
american_scientific_journal-4355	317	8	the	the	DET
american_scientific_journal-4355	317	9	membranous	membranous	ADJ
american_scientific_journal-4355	317	10	part	part	NOUN
american_scientific_journal-4355	317	11	heparan	heparan	ADJ
american_scientific_journal-4355	317	12	sulphate	sulphate	NOUN
american_scientific_journal-4355	317	13	acts	act	NOUN
american_scientific_journal-4355	317	14	as	as	ADP
american_scientific_journal-4355	317	15	a	a	DET
american_scientific_journal-4355	317	16	reservoir	reservoir	NOUN
american_scientific_journal-4355	317	17	of	of	ADP
american_scientific_journal-4355	317	18	ligand	ligand	NOUN
american_scientific_journal-4355	317	19	for	for	ADP
american_scientific_journal-4355	317	20	tgf	tgf	PROPN
american_scientific_journal-4355	317	21	-	-	PUNCT
american_scientific_journal-4355	317	22	beta	beta	NOUN
american_scientific_journal-4355	317	23	receptors.thirdly	receptors.thirdly	ADV
american_scientific_journal-4355	317	24	,	,	PUNCT
american_scientific_journal-4355	317	25	this	this	DET
american_scientific_journal-4355	317	26	work	work	NOUN
american_scientific_journal-4355	317	27	used	use	VERB
american_scientific_journal-4355	317	28	immortalized	immortalize	VERB
american_scientific_journal-4355	317	29	hk2	hk2	NOUN
american_scientific_journal-4355	317	30	cells	cell	NOUN
american_scientific_journal-4355	317	31	as	as	ADP
american_scientific_journal-4355	317	32	a	a	DET
american_scientific_journal-4355	317	33	predictor	predictor	NOUN
american_scientific_journal-4355	317	34	of	of	ADP
american_scientific_journal-4355	317	35	renal	renal	ADJ
american_scientific_journal-4355	317	36	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	317	37	,	,	PUNCT
american_scientific_journal-4355	317	38	but	but	CCONJ
american_scientific_journal-4355	317	39	the	the	DET
american_scientific_journal-4355	317	40	other	other	ADJ
american_scientific_journal-4355	317	41	predictor	predictor	NOUN
american_scientific_journal-4355	317	42	of	of	ADP
american_scientific_journal-4355	317	43	outcome	outcome	NOUN
american_scientific_journal-4355	317	44	in	in	ADP
american_scientific_journal-4355	317	45	the	the	DET
american_scientific_journal-4355	317	46	kidney	kidney	NOUN
american_scientific_journal-4355	317	47	,	,	PUNCT
american_scientific_journal-4355	317	48	regardless	regardless	ADV
american_scientific_journal-4355	317	49	of	of	ADP
american_scientific_journal-4355	317	50	disease	disease	NOUN
american_scientific_journal-4355	317	51	aetiology	aetiology	NOUN
american_scientific_journal-4355	317	52	,	,	PUNCT
american_scientific_journal-4355	317	53	is	be	AUX
american_scientific_journal-4355	317	54	the	the	DET
american_scientific_journal-4355	317	55	presence	presence	NOUN
american_scientific_journal-4355	317	56	of	of	ADP
american_scientific_journal-4355	317	57	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	317	58	which	which	PRON
american_scientific_journal-4355	317	59	was	be	AUX
american_scientific_journal-4355	317	60	not	not	PART
american_scientific_journal-4355	317	61	studied	study	VERB
american_scientific_journal-4355	317	62	.	.	PUNCT
american_scientific_journal-4355	318	1	finally	finally	ADV
american_scientific_journal-4355	318	2	,	,	PUNCT
american_scientific_journal-4355	318	3	this	this	DET
american_scientific_journal-4355	318	4	work	work	NOUN
american_scientific_journal-4355	318	5	also	also	ADV
american_scientific_journal-4355	318	6	needs	need	VERB
american_scientific_journal-4355	318	7	to	to	PART
american_scientific_journal-4355	318	8	be	be	AUX
american_scientific_journal-4355	318	9	applied	apply	VERB
american_scientific_journal-4355	318	10	to	to	ADP
american_scientific_journal-4355	318	11	and	and	CCONJ
american_scientific_journal-4355	318	12	practiced	practice	VERB
american_scientific_journal-4355	318	13	in	in	ADP
american_scientific_journal-4355	318	14	animal	animal	NOUN
american_scientific_journal-4355	318	15	research	research	NOUN
american_scientific_journal-4355	318	16	to	to	PART
american_scientific_journal-4355	318	17	get	get	VERB
american_scientific_journal-4355	318	18	the	the	DET
american_scientific_journal-4355	318	19	best	good	ADJ
american_scientific_journal-4355	318	20	results	result	NOUN
american_scientific_journal-4355	318	21	,	,	PUNCT
american_scientific_journal-4355	318	22	as	as	SCONJ
american_scientific_journal-4355	318	23	the	the	DET
american_scientific_journal-4355	318	24	hk2	hk2	PROPN
american_scientific_journal-4355	318	25	cells	cell	NOUN
american_scientific_journal-4355	318	26	have	have	AUX
american_scientific_journal-4355	318	27	been	be	AUX
american_scientific_journal-4355	318	28	grown	grow	VERB
american_scientific_journal-4355	318	29	in	in	ADP
american_scientific_journal-4355	318	30	their	their	PRON
american_scientific_journal-4355	318	31	normal	normal	ADJ
american_scientific_journal-4355	318	32	environment	environment	NOUN
american_scientific_journal-4355	318	33	and	and	CCONJ
american_scientific_journal-4355	318	34	could	could	AUX
american_scientific_journal-4355	318	35	express	express	VERB
american_scientific_journal-4355	318	36	any	any	DET
american_scientific_journal-4355	318	37	change	change	NOUN
american_scientific_journal-4355	318	38	that	that	PRON
american_scientific_journal-4355	318	39	might	might	AUX
american_scientific_journal-4355	318	40	happen	happen	VERB
american_scientific_journal-4355	318	41	in	in	ADP
american_scientific_journal-4355	318	42	vivo	vivo	NOUN
american_scientific_journal-4355	318	43	.	.	PUNCT
american_scientific_journal-4355	319	1	5	5	X
american_scientific_journal-4355	319	2	.	.	PUNCT
american_scientific_journal-4355	319	3	the	the	DET
american_scientific_journal-4355	319	4	overall	overall	ADJ
american_scientific_journal-4355	319	5	conclusion	conclusion	NOUN
american_scientific_journal-4355	319	6	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	319	7	can	can	AUX
american_scientific_journal-4355	319	8	be	be	AUX
american_scientific_journal-4355	319	9	expressed	express	VERB
american_scientific_journal-4355	319	10	by	by	ADP
american_scientific_journal-4355	319	11	hk2	hk2	PROPN
american_scientific_journal-4355	319	12	cells	cell	NOUN
american_scientific_journal-4355	319	13	spontaneously	spontaneously	ADV
american_scientific_journal-4355	319	14	or	or	CCONJ
american_scientific_journal-4355	319	15	by	by	ADP
american_scientific_journal-4355	319	16	inflammatory	inflammatory	ADJ
american_scientific_journal-4355	319	17	cytokines	cytokine	NOUN
american_scientific_journal-4355	319	18	and	and	CCONJ
american_scientific_journal-4355	319	19	can	can	AUX
american_scientific_journal-4355	319	20	also	also	ADV
american_scientific_journal-4355	319	21	be	be	AUX
american_scientific_journal-4355	319	22	inhibited	inhibit	VERB
american_scientific_journal-4355	319	23	by	by	ADP
american_scientific_journal-4355	319	24	sirna	sirna	PROPN
american_scientific_journal-4355	319	25	,	,	PUNCT
american_scientific_journal-4355	319	26	p	p	PROPN
american_scientific_journal-4355	319	27	-	-	PUNCT
american_scientific_journal-4355	319	28	nitrophenyl	nitrophenyl	NOUN
american_scientific_journal-4355	319	29	-	-	PUNCT
american_scientific_journal-4355	319	30	β	β	NOUN
american_scientific_journal-4355	319	31	-	-	ADJ
american_scientific_journal-4355	319	32	d	d	NOUN
american_scientific_journal-4355	319	33	-	-	PUNCT
american_scientific_journal-4355	319	34	xylopyranoside	xylopyranoside	ADJ
american_scientific_journal-4355	319	35	,	,	PUNCT
american_scientific_journal-4355	319	36	and	and	CCONJ
american_scientific_journal-4355	319	37	ameliorate	ameliorate	VERB
american_scientific_journal-4355	319	38	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	319	39	as	as	ADV
american_scientific_journal-4355	319	40	well	well	ADV
american_scientific_journal-4355	319	41	as	as	ADP
american_scientific_journal-4355	319	42	cancer	cancer	NOUN
american_scientific_journal-4355	319	43	through	through	ADP
american_scientific_journal-4355	319	44	a	a	DET
american_scientific_journal-4355	319	45	group	group	NOUN
american_scientific_journal-4355	319	46	of	of	ADP
american_scientific_journal-4355	319	47	multiple	multiple	ADJ
american_scientific_journal-4355	319	48	regulatory	regulatory	ADJ
american_scientific_journal-4355	319	49	mechanisms	mechanism	NOUN
american_scientific_journal-4355	319	50	towards	towards	ADP
american_scientific_journal-4355	319	51	tgf	tgf	PROPN
american_scientific_journal-4355	319	52	-	-	PUNCT
american_scientific_journal-4355	319	53	β1	β1	PROPN
american_scientific_journal-4355	319	54	signalling	signal	VERB
american_scientific_journal-4355	319	55	and	and	CCONJ
american_scientific_journal-4355	319	56	also	also	ADV
american_scientific_journal-4355	319	57	could	could	AUX
american_scientific_journal-4355	319	58	contributes	contribute	VERB
american_scientific_journal-4355	319	59	to	to	ADP
american_scientific_journal-4355	319	60	emt	emt	PROPN
american_scientific_journal-4355	319	61	.	.	PUNCT
american_scientific_journal-4355	320	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	320	2	acts	act	VERB
american_scientific_journal-4355	320	3	as	as	ADP
american_scientific_journal-4355	320	4	apotential	apotential	ADJ
american_scientific_journal-4355	320	5	regulator	regulator	NOUN
american_scientific_journal-4355	320	6	of	of	ADP
american_scientific_journal-4355	320	7	tgfβ1	tgfβ1	NOUN
american_scientific_journal-4355	320	8	signalling	signal	VERB
american_scientific_journal-4355	320	9	in	in	ADP
american_scientific_journal-4355	320	10	the	the	DET
american_scientific_journal-4355	320	11	kidney	kidney	NOUN
american_scientific_journal-4355	320	12	.	.	PUNCT
american_scientific_journal-4355	321	1	6	6	X
american_scientific_journal-4355	321	2	.	.	X
american_scientific_journal-4355	321	3	recommendations	recommendation	NOUN
american_scientific_journal-4355	321	4	these	these	DET
american_scientific_journal-4355	321	5	groups	group	NOUN
american_scientific_journal-4355	321	6	of	of	ADP
american_scientific_journal-4355	321	7	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	321	8	actions	action	NOUN
american_scientific_journal-4355	321	9	will	will	AUX
american_scientific_journal-4355	321	10	have	have	VERB
american_scientific_journal-4355	321	11	a	a	DET
american_scientific_journal-4355	321	12	potential	potential	ADJ
american_scientific_journal-4355	321	13	impact	impact	NOUN
american_scientific_journal-4355	321	14	on	on	ADP
american_scientific_journal-4355	321	15	tgf	tgf	PROPN
american_scientific_journal-4355	321	16	-	-	PUNCT
american_scientific_journal-4355	321	17	β	β	NOUN
american_scientific_journal-4355	321	18	,	,	PUNCT
american_scientific_journal-4355	321	19	which	which	PRON
american_scientific_journal-4355	321	20	is	be	AUX
american_scientific_journal-4355	321	21	the	the	DET
american_scientific_journal-4355	321	22	key	key	ADJ
american_scientific_journal-4355	321	23	factor	factor	NOUN
american_scientific_journal-4355	321	24	in	in	ADP
american_scientific_journal-4355	321	25	renal	renal	ADJ
american_scientific_journal-4355	321	26	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	321	27	and	and	CCONJ
american_scientific_journal-4355	321	28	when	when	SCONJ
american_scientific_journal-4355	321	29	combined	combine	VERB
american_scientific_journal-4355	321	30	together	together	ADV
american_scientific_journal-4355	321	31	they	they	PRON
american_scientific_journal-4355	321	32	will	will	AUX
american_scientific_journal-4355	321	33	provide	provide	VERB
american_scientific_journal-4355	321	34	a	a	DET
american_scientific_journal-4355	321	35	new	new	ADJ
american_scientific_journal-4355	321	36	weapon	weapon	NOUN
american_scientific_journal-4355	321	37	in	in	ADP
american_scientific_journal-4355	321	38	the	the	DET
american_scientific_journal-4355	321	39	treatment	treatment	NOUN
american_scientific_journal-4355	321	40	of	of	ADP
american_scientific_journal-4355	321	41	kidney	kidney	NOUN
american_scientific_journal-4355	321	42	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	321	43	.	.	PUNCT
american_scientific_journal-4355	322	1	references	reference	NOUN
american_scientific_journal-4355	322	2	[	[	X
american_scientific_journal-4355	322	3	1	1	NUM
american_scientific_journal-4355	322	4	]	]	PUNCT
american_scientific_journal-4355	322	5	.bottinger	.bottinger	PUNCT
american_scientific_journal-4355	323	1	e.	e.	PROPN
american_scientific_journal-4355	323	2	p	p	PROPN
american_scientific_journal-4355	323	3	,	,	PUNCT
american_scientific_journal-4355	323	4	bitzer	bitzer	PROPN
american_scientific_journal-4355	323	5	m	m	PROPN
american_scientific_journal-4355	323	6	(	(	PUNCT
american_scientific_journal-4355	323	7	2002	2002	NUM
american_scientific_journal-4355	323	8	)	)	PUNCT
american_scientific_journal-4355	323	9	.	.	PUNCT
american_scientific_journal-4355	324	1	tgf	tgf	NOUN
american_scientific_journal-4355	324	2	-	-	PUNCT
american_scientific_journal-4355	324	3	beta	beta	NOUN
american_scientific_journal-4355	324	4	signaling	signal	VERB
american_scientific_journal-4355	324	5	in	in	ADP
american_scientific_journal-4355	324	6	renal	renal	ADJ
american_scientific_journal-4355	324	7	diseaseˮ	diseaseˮ	PROPN
american_scientific_journal-4355	324	8	j	j	PROPN
american_scientific_journal-4355	324	9	am	be	AUX
american_scientific_journal-4355	324	10	soc	soc	NOUN
american_scientific_journal-4355	324	11	nephrol	nephrol	NOUN
american_scientific_journal-4355	324	12	.	.	PUNCT
american_scientific_journal-4355	325	1	2002	2002	NUM
american_scientific_journal-4355	325	2	oct;13(10):2600	oct;13(10):2600	NOUN
american_scientific_journal-4355	325	3	-	-	SYM
american_scientific_journal-4355	325	4	10	10	NUM
american_scientific_journal-4355	325	5	.	.	PUNCT
american_scientific_journal-4355	326	1	[	[	X
american_scientific_journal-4355	326	2	2	2	X
american_scientific_journal-4355	326	3	]	]	PUNCT
american_scientific_journal-4355	326	4	.chen	.chen	X
american_scientific_journal-4355	326	5	c.l	c.l	PROPN
american_scientific_journal-4355	326	6	.	.	PROPN
american_scientific_journal-4355	326	7	,	,	PUNCT
american_scientific_journal-4355	326	8	huang	huang	PROPN
american_scientific_journal-4355	326	9	s.s	s.s	PROPN
american_scientific_journal-4355	326	10	.	.	PROPN
american_scientific_journal-4355	326	11	,	,	PUNCT
american_scientific_journal-4355	326	12	and	and	CCONJ
american_scientific_journal-4355	326	13	huang	huang	PROPN
american_scientific_journal-4355	326	14	j.s	j.s	PROPN
american_scientific_journal-4355	326	15	.	.	PUNCT
american_scientific_journal-4355	326	16	(	(	PUNCT
american_scientific_journal-4355	326	17	2006	2006	NUM
american_scientific_journal-4355	326	18	)	)	PUNCT
american_scientific_journal-4355	326	19	.	.	PUNCT
american_scientific_journal-4355	327	1	cellular	cellular	ADJ
american_scientific_journal-4355	327	2	heparan	heparan	ADJ
american_scientific_journal-4355	327	3	sulfate	sulfate	NOUN
american_scientific_journal-4355	327	4	negatively	negatively	ADV
american_scientific_journal-4355	327	5	modulates	modulate	VERB
american_scientific_journal-4355	327	6	transforming	transform	VERB
american_scientific_journal-4355	327	7	growth	growth	NOUN
american_scientific_journal-4355	327	8	factor	factor	NOUN
american_scientific_journal-4355	327	9	-	-	PUNCT
american_scientific_journal-4355	327	10	beta1	beta1	NOUN
american_scientific_journal-4355	327	11	(	(	PUNCT
american_scientific_journal-4355	327	12	tgf	tgf	NOUN
american_scientific_journal-4355	327	13	-	-	PUNCT
american_scientific_journal-4355	327	14	beta1	beta1	NOUN
american_scientific_journal-4355	327	15	)	)	PUNCT
american_scientific_journal-4355	327	16	responsiveness	responsiveness	NOUN
american_scientific_journal-4355	327	17	in	in	ADP
american_scientific_journal-4355	327	18	epithelial	epithelial	ADJ
american_scientific_journal-4355	327	19	cells	cell	NOUN
american_scientific_journal-4355	327	20	.	.	PUNCT
american_scientific_journal-4355	328	1	j	j	PROPN
american_scientific_journal-4355	328	2	biol	biol	PROPN
american_scientific_journal-4355	328	3	chem	chem	PROPN
american_scientific_journal-4355	328	4	.	.	PUNCT
american_scientific_journal-4355	329	1	apr	apr	PROPN
american_scientific_journal-4355	329	2	28;281(17):11506	28;281(17):11506	NUM
american_scientific_journal-4355	329	3	-	-	SYM
american_scientific_journal-4355	329	4	14	14	NUM
american_scientific_journal-4355	329	5	.	.	PUNCT
american_scientific_journal-4355	330	1	[	[	X
american_scientific_journal-4355	330	2	3	3	NUM
american_scientific_journal-4355	330	3	]	]	PUNCT
american_scientific_journal-4355	330	4	.	.	PUNCT
american_scientific_journal-4355	331	1	hopkins	hopkins	PROPN
american_scientific_journal-4355	331	2	a.l	a.l	PROPN
american_scientific_journal-4355	331	3	.	.	PROPN
american_scientific_journal-4355	331	4	,	,	PUNCT
american_scientific_journal-4355	331	5	and	and	CCONJ
american_scientific_journal-4355	331	6	groom	groom	NOUN
american_scientific_journal-4355	331	7	c.r	c.r	PROPN
american_scientific_journal-4355	331	8	.	.	PROPN
american_scientific_journal-4355	331	9	(	(	PUNCT
american_scientific_journal-4355	331	10	2002	2002	NUM
american_scientific_journal-4355	331	11	)	)	PUNCT
american_scientific_journal-4355	331	12	.	.	PUNCT
american_scientific_journal-4355	332	1	the	the	DET
american_scientific_journal-4355	332	2	druggable	druggable	ADJ
american_scientific_journal-4355	332	3	genome	genome	NOUN
american_scientific_journal-4355	332	4	.	.	PUNCT
american_scientific_journal-4355	333	1	nature	nature	NOUN
american_scientific_journal-4355	333	2	reviews	review	NOUN
american_scientific_journal-4355	333	3	.	.	PUNCT
american_scientific_journal-4355	334	1	drug	drug	NOUN
american_scientific_journal-4355	334	2	discovery	discovery	PROPN
american_scientific_journal-4355	334	3	,	,	PUNCT
american_scientific_journal-4355	334	4	1(9):727	1(9):727	NUM
american_scientific_journal-4355	334	5	-	-	SYM
american_scientific_journal-4355	334	6	30	30	NUM
american_scientific_journal-4355	334	7	.	.	PUNCT
american_scientific_journal-4355	335	1	[	[	X
american_scientific_journal-4355	335	2	4	4	X
american_scientific_journal-4355	335	3	]	]	PUNCT
american_scientific_journal-4355	335	4	.downer	.downer	PUNCT
american_scientific_journal-4355	335	5	g.	g.	NOUN
american_scientific_journal-4355	335	6	,	,	PUNCT
american_scientific_journal-4355	335	7	phan	phan	PROPN
american_scientific_journal-4355	335	8	s.	s.	PROPN
american_scientific_journal-4355	335	9	h.	h.	PROPN
american_scientific_journal-4355	335	10	,	,	PUNCT
american_scientific_journal-4355	335	11	et	et	PROPN
american_scientific_journal-4355	335	12	al	al	PROPN
american_scientific_journal-4355	335	13	.	.	PUNCT
american_scientific_journal-4355	335	14	(	(	PUNCT
american_scientific_journal-4355	335	15	1988	1988	NUM
american_scientific_journal-4355	335	16	)	)	PUNCT
american_scientific_journal-4355	335	17	.	.	PUNCT
american_scientific_journal-4355	336	1	analysis	analysis	NOUN
american_scientific_journal-4355	336	2	of	of	ADP
american_scientific_journal-4355	336	3	renal	renal	ADJ
american_scientific_journal-4355	336	4	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	336	5	in	in	ADP
american_scientific_journal-4355	336	6	rabbit	rabbit	NOUN
american_scientific_journal-4355	336	7	model	model	NOUN
american_scientific_journal-4355	336	8	of	of	ADP
american_scientific_journal-4355	336	9	crescentic	crescentic	ADJ
american_scientific_journal-4355	336	10	nephritis	nephritis	PROPN
american_scientific_journal-4355	336	11	clin	clin	PROPN
american_scientific_journal-4355	336	12	invest	invest	VERB
american_scientific_journal-4355	336	13	82(3	82(3	NUM
american_scientific_journal-4355	336	14	):	):	PUNCT
american_scientific_journal-4355	336	15	998	998	NUM
american_scientific_journal-4355	336	16	-	-	SYM
american_scientific_journal-4355	336	17	1006	1006	NUM
american_scientific_journal-4355	336	18	[	[	X
american_scientific_journal-4355	336	19	5	5	NUM
american_scientific_journal-4355	336	20	]	]	PUNCT
american_scientific_journal-4355	336	21	.fukagawa	.fukagawa	PRON
american_scientific_journal-4355	336	22	m.	m.	NOUN
american_scientific_journal-4355	336	23	,	,	PUNCT
american_scientific_journal-4355	336	24	noda	noda	PROPN
american_scientific_journal-4355	336	25	m.	m.	PROPN
american_scientific_journal-4355	336	26	,	,	PUNCT
american_scientific_journal-4355	336	27	shimizu	shimizu	PROPN
american_scientific_journal-4355	336	28	t.	t.	PROPN
american_scientific_journal-4355	336	29	,	,	PUNCT
american_scientific_journal-4355	336	30	and	and	CCONJ
american_scientific_journal-4355	336	31	kurokawa	kurokawa	PROPN
american_scientific_journal-4355	336	32	k.	k.	PROPN
american_scientific_journal-4355	337	1	(	(	PUNCT
american_scientific_journal-4355	337	2	1999	1999	NUM
american_scientific_journal-4355	337	3	)	)	PUNCT
american_scientific_journal-4355	337	4	chronic	chronic	ADJ
american_scientific_journal-4355	337	5	progressive	progressive	ADJ
american_scientific_journal-4355	337	6	interstitial	interstitial	ADJ
american_scientific_journal-4355	337	7	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	337	8	in	in	ADP
american_scientific_journal-4355	337	9	renal	renal	ADJ
american_scientific_journal-4355	337	10	disease	disease	NOUN
american_scientific_journal-4355	337	11	—	—	PUNCT
american_scientific_journal-4355	337	12	are	be	AUX
american_scientific_journal-4355	337	13	there	there	PRON
american_scientific_journal-4355	337	14	novel	novel	ADJ
american_scientific_journal-4355	337	15	pharmacological	pharmacological	ADJ
american_scientific_journal-4355	337	16	approaches	approach	NOUN
american_scientific_journal-4355	337	17	?	?	PUNCT
american_scientific_journal-4355	337	18	,	,	PUNCT
american_scientific_journal-4355	337	19	nephrol	nephrol	ADJ
american_scientific_journal-4355	337	20	dial	dial	NOUN
american_scientific_journal-4355	337	21	transplant	transplant	NOUN
american_scientific_journal-4355	337	22	14	14	NUM
american_scientific_journal-4355	337	23	:	:	PUNCT
american_scientific_journal-4355	337	24	2793	2793	NUM
american_scientific_journal-4355	337	25	-	-	SYM
american_scientific_journal-4355	337	26	2795	2795	NUM
american_scientific_journal-4355	337	27	.	.	PUNCT
american_scientific_journal-4355	338	1	[	[	X
american_scientific_journal-4355	338	2	6].soma	6].soma	NUM
american_scientific_journal-4355	338	3	meran	meran	VERB
american_scientific_journal-4355	338	4	and	and	CCONJ
american_scientific_journal-4355	338	5	robert	robert	PROPN
american_scientific_journal-4355	338	6	steadman	steadman	PROPN
american_scientific_journal-4355	338	7	,	,	PUNCT
american_scientific_journal-4355	338	8	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	338	9	and	and	CCONJ
american_scientific_journal-4355	338	10	myofibroblasts	myofibroblast	NOUN
american_scientific_journal-4355	338	11	in	in	ADP
american_scientific_journal-4355	338	12	renal	renal	ADJ
american_scientific_journal-4355	338	13	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	338	14	.	.	PUNCT
american_scientific_journal-4355	339	1	2011	2011	NUM
american_scientific_journal-4355	339	2	https://doi.org/10.1111/j.1365-2613.2011.00764.x	https://doi.org/10.1111/j.1365-2613.2011.00764.x	NUM
american_scientific_journal-4355	339	3	.	.	PUNCT
american_scientific_journal-4355	340	1	[	[	X
american_scientific_journal-4355	340	2	7	7	NUM
american_scientific_journal-4355	340	3	]	]	X
american_scientific_journal-4355	340	4	.bohle	.bohle	ADJ
american_scientific_journal-4355	340	5	a.	a.	NOUN
american_scientific_journal-4355	340	6	,	,	PUNCT
american_scientific_journal-4355	340	7	muller	muller	PROPN
american_scientific_journal-4355	340	8	ga	ga	PROPN
american_scientific_journal-4355	340	9	.	.	PROPN
american_scientific_journal-4355	340	10	,	,	PUNCT
american_scientific_journal-4355	340	11	wehrmann	wehrmann	PROPN
american_scientific_journal-4355	340	12	m.	m.	PROPN
american_scientific_journal-4355	340	13	,	,	PUNCT
american_scientific_journal-4355	340	14	mackensen	mackensen	PROPN
american_scientific_journal-4355	340	15	-	-	PUNCT
american_scientific_journal-4355	340	16	haen	haen	NOUN
american_scientific_journal-4355	340	17	s	s	PROPN
american_scientific_journal-4355	340	18	,	,	PUNCT
american_scientific_journal-4355	340	19	et	et	PROPN
american_scientific_journal-4355	340	20	al	al	PROPN
american_scientific_journal-4355	340	21	(	(	PUNCT
american_scientific_journal-4355	340	22	1996	1996	NUM
american_scientific_journal-4355	340	23	)	)	PUNCT
american_scientific_journal-4355	340	24	.	.	PUNCT
american_scientific_journal-4355	341	1	pathogenesis	pathogenesis	NOUN
american_scientific_journal-4355	341	2	of	of	ADP
american_scientific_journal-4355	341	3	chronic	chronic	ADJ
american_scientific_journal-4355	341	4	renal	renal	ADJ
american_scientific_journal-4355	341	5	failure	failure	NOUN
american_scientific_journal-4355	341	6	in	in	ADP
american_scientific_journal-4355	341	7	the	the	DET
american_scientific_journal-4355	341	8	primary	primary	ADJ
american_scientific_journal-4355	341	9	glomerulopathies	glomerulopathie	NOUN
american_scientific_journal-4355	341	10	,	,	PUNCT
american_scientific_journal-4355	341	11	renal	renal	ADJ
american_scientific_journal-4355	341	12	vasculopathies	vasculopathie	NOUN
american_scientific_journal-4355	341	13	,	,	PUNCT
american_scientific_journal-4355	341	14	and	and	CCONJ
american_scientific_journal-4355	341	15	chronic	chronic	ADJ
american_scientific_journal-4355	341	16	interstitial	interstitial	ADJ
american_scientific_journal-4355	341	17	nephritides	nephritide	NOUN
american_scientific_journal-4355	341	18	.	.	PUNCT
american_scientific_journal-4355	342	1	kidney	kidney	PROPN
american_scientific_journal-4355	342	2	int	int	PROPN
american_scientific_journal-4355	342	3	,	,	PUNCT
american_scientific_journal-4355	342	4	54	54	NUM
american_scientific_journal-4355	342	5	:	:	PUNCT
american_scientific_journal-4355	342	6	s2	s2	VERB
american_scientific_journal-4355	342	7	-	-	PUNCT
american_scientific_journal-4355	342	8	9	9	NUM
american_scientific_journal-4355	342	9	.	.	PUNCT
american_scientific_journal-4355	343	1	[	[	X
american_scientific_journal-4355	343	2	8	8	NUM
american_scientific_journal-4355	343	3	]	]	PUNCT
american_scientific_journal-4355	343	4	.wang	.wang	PROPN
american_scientific_journal-4355	343	5	shi	shi	PROPN
american_scientific_journal-4355	343	6	-	-	PUNCT
american_scientific_journal-4355	343	7	nong	nong	PROPN
american_scientific_journal-4355	343	8	.	.	PROPN
american_scientific_journal-4355	343	9	,	,	PUNCT
american_scientific_journal-4355	343	10	and	and	CCONJ
american_scientific_journal-4355	343	11	hirschberg	hirschberg	ADP
american_scientific_journal-4355	343	12	raimund.(1999	raimund.(1999	NOUN
american_scientific_journal-4355	343	13	)	)	PUNCT
american_scientific_journal-4355	343	14	,	,	PUNCT
american_scientific_journal-4355	343	15	tubular	tubular	ADJ
american_scientific_journal-4355	343	16	epithelial	epithelial	ADJ
american_scientific_journal-4355	343	17	cell	cell	NOUN
american_scientific_journal-4355	343	18	activation	activation	NOUN
american_scientific_journal-4355	343	19	and	and	CCONJ
american_scientific_journal-4355	343	20	interstitial	interstitial	ADJ
american_scientific_journal-4355	343	21	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	343	22	.	.	PUNCT
american_scientific_journal-4355	344	1	the	the	DET
american_scientific_journal-4355	344	2	role	role	NOUN
american_scientific_journal-4355	344	3	of	of	ADP
american_scientific_journal-4355	344	4	glomerular	glomerular	ADJ
american_scientific_journal-4355	344	5	ultrafiltration	ultrafiltration	NOUN
american_scientific_journal-4355	344	6	of	of	ADP
american_scientific_journal-4355	344	7	growth	growth	NOUN
american_scientific_journal-4355	344	8	factors	factor	NOUN
american_scientific_journal-4355	344	9	in	in	ADP
american_scientific_journal-4355	344	10	the	the	DET
american_scientific_journal-4355	344	11	nephrotic	nephrotic	ADJ
american_scientific_journal-4355	344	12	syndrome	syndrome	NOUN
american_scientific_journal-4355	344	13	and	and	CCONJ
american_scientific_journal-4355	344	14	diabetic	diabetic	ADJ
american_scientific_journal-4355	344	15	nephropathy	nephropathy	NOUN
american_scientific_journal-4355	344	16	.	.	PUNCT
american_scientific_journal-4355	345	1	nephrol	nephrol	PROPN
american_scientific_journal-4355	345	2	dial	dial	NOUN
american_scientific_journal-4355	345	3	transplant	transplant	NOUN
american_scientific_journal-4355	345	4	,	,	PUNCT
american_scientific_journal-4355	345	5	14	14	NUM
american_scientific_journal-4355	345	6	:	:	PUNCT
american_scientific_journal-4355	345	7	2072	2072	NUM
american_scientific_journal-4355	345	8	-	-	SYM
american_scientific_journal-4355	345	9	2074	2074	NUM
american_scientific_journal-4355	345	10	.	.	PUNCT
american_scientific_journal-4355	346	1	[	[	X
american_scientific_journal-4355	346	2	9	9	NUM
american_scientific_journal-4355	346	3	]	]	X
american_scientific_journal-4355	346	4	strutz	strutz	ADJ
american_scientific_journal-4355	346	5	.	.	PUNCT
american_scientific_journal-4355	347	1	novel	novel	ADJ
american_scientific_journal-4355	347	2	aspects	aspect	NOUN
american_scientific_journal-4355	347	3	of	of	ADP
american_scientific_journal-4355	347	4	renal	renal	ADJ
american_scientific_journal-4355	347	5	fibrogenesis	fibrogenesis	NOUN
american_scientific_journal-4355	347	6	.	.	PUNCT
american_scientific_journal-4355	348	1	nephrol	nephrol	PROPN
american_scientific_journal-4355	348	2	dial	dial	NOUN
american_scientific_journal-4355	348	3	transplant	transplant	NOUN
american_scientific_journal-4355	348	4	(	(	PUNCT
american_scientific_journal-4355	348	5	1995	1995	NUM
american_scientific_journal-4355	348	6	)	)	PUNCT
american_scientific_journal-4355	348	7	10	10	NUM
american_scientific_journal-4355	348	8	:	:	SYM
american_scientific_journal-4355	348	9	1526	1526	NUM
american_scientific_journal-4355	348	10	-	-	SYM
american_scientific_journal-4355	348	11	1532	1532	NUM
american_scientific_journal-4355	348	12	[	[	X
american_scientific_journal-4355	348	13	10	10	NUM
american_scientific_journal-4355	348	14	]	]	PUNCT
american_scientific_journal-4355	348	15	nahas	nahas	PROPN
american_scientific_journal-4355	348	16	a.m.e	a.m.e	PROPN
american_scientific_journal-4355	348	17	.	.	PROPN
american_scientific_journal-4355	348	18	,	,	PUNCT
american_scientific_journal-4355	348	19	muchaneta	muchaneta	PROPN
american_scientific_journal-4355	348	20	-	-	PUNCT
american_scientific_journal-4355	348	21	kubara	kubara	PROPN
american_scientific_journal-4355	348	22	e.c	e.c	PROPN
american_scientific_journal-4355	348	23	.	.	PROPN
american_scientific_journal-4355	348	24	,	,	PUNCT
american_scientific_journal-4355	348	25	zhang	zhang	PROPN
american_scientific_journal-4355	348	26	g.	g.	PROPN
american_scientific_journal-4355	348	27	,	,	PUNCT
american_scientific_journal-4355	348	28	adam	adam	PROPN
american_scientific_journal-4355	348	29	a.	a.	PROPN
american_scientific_journal-4355	348	30	,	,	PUNCT
american_scientific_journal-4355	348	31	et	et	PROPN
american_scientific_journal-4355	348	32	al	al	PROPN
american_scientific_journal-4355	348	33	.	.	PUNCT
american_scientific_journal-4355	348	34	(	(	PUNCT
american_scientific_journal-4355	348	35	1996	1996	NUM
american_scientific_journal-4355	348	36	)	)	PUNCT
american_scientific_journal-4355	348	37	,	,	PUNCT
american_scientific_journal-4355	348	38	phenotypic	phenotypic	ADJ
american_scientific_journal-4355	348	39	modulation	modulation	NOUN
american_scientific_journal-4355	348	40	of	of	ADP
american_scientific_journal-4355	348	41	renal	renal	ADJ
american_scientific_journal-4355	348	42	cells	cell	NOUN
american_scientific_journal-4355	348	43	during	during	ADP
american_scientific_journal-4355	348	44	experimental	experimental	ADJ
american_scientific_journal-4355	348	45	and	and	CCONJ
american_scientific_journal-4355	348	46	clinical	clinical	ADJ
american_scientific_journal-4355	348	47	renal	renal	ADJ
american_scientific_journal-4355	348	48	scarring	scarring	NOUN
american_scientific_journal-4355	348	49	.	.	PUNCT
american_scientific_journal-4355	349	1	kidney	kidney	NOUN
american_scientific_journal-4355	349	2	int	int	NOUN
american_scientific_journal-4355	349	3	;	;	PUNCT
american_scientific_journal-4355	349	4	49	49	NUM
american_scientific_journal-4355	349	5	:	:	PUNCT
american_scientific_journal-4355	349	6	s23	s23	NOUN
american_scientific_journal-4355	349	7	-	-	PUNCT
american_scientific_journal-4355	349	8	27	27	NUM
american_scientific_journal-4355	349	9	.	.	PUNCT
american_scientific_journal-4355	350	1	[	[	X
american_scientific_journal-4355	350	2	11	11	NUM
american_scientific_journal-4355	350	3	]	]	X
american_scientific_journal-4355	350	4	struz	struz	PROPN
american_scientific_journal-4355	350	5	f.	f.	PROPN
american_scientific_journal-4355	350	6	,	,	PUNCT
american_scientific_journal-4355	350	7	okada	okada	PROPN
american_scientific_journal-4355	350	8	h.	h.	PROPN
american_scientific_journal-4355	350	9	,	,	PUNCT
american_scientific_journal-4355	350	10	and	and	CCONJ
american_scientific_journal-4355	350	11	lo	lo	PROPN
american_scientific_journal-4355	350	12	c.w	c.w	PROPN
american_scientific_journal-4355	350	13	.	.	PROPN
american_scientific_journal-4355	350	14	,	,	PUNCT
american_scientific_journal-4355	350	15	et	et	PROPN
american_scientific_journal-4355	350	16	al	al	PROPN
american_scientific_journal-4355	350	17	.	.	PROPN
american_scientific_journal-4355	350	18	(	(	PUNCT
american_scientific_journal-4355	350	19	1995	1995	NUM
american_scientific_journal-4355	350	20	)	)	PUNCT
american_scientific_journal-4355	350	21	.	.	PUNCT
american_scientific_journal-4355	351	1	identification	identification	NOUN
american_scientific_journal-4355	351	2	and	and	CCONJ
american_scientific_journal-4355	351	3	characterization	characterization	NOUN
american_scientific_journal-4355	351	4	of	of	ADP
american_scientific_journal-4355	351	5	a	a	DET
american_scientific_journal-4355	351	6	fibroblast	fibroblast	ADJ
american_scientific_journal-4355	351	7	marker	marker	NOUN
american_scientific_journal-4355	351	8	:	:	PUNCT
american_scientific_journal-4355	351	9	fsp1	fsp1	PROPN
american_scientific_journal-4355	351	10	.	.	PUNCT
american_scientific_journal-4355	352	1	j	j	PROPN
american_scientific_journal-4355	352	2	cell	cell	NOUN
american_scientific_journal-4355	352	3	biol	biol	PROPN
american_scientific_journal-4355	352	4	;	;	PUNCT
american_scientific_journal-4355	352	5	130	130	NUM
american_scientific_journal-4355	352	6	:	:	PUNCT
american_scientific_journal-4355	352	7	393–405	393–405	NUM
american_scientific_journal-4355	352	8	.	.	PUNCT
american_scientific_journal-4355	353	1	[	[	X
american_scientific_journal-4355	353	2	12]yang	12]yang	NUM
american_scientific_journal-4355	353	3	j.	j.	PROPN
american_scientific_journal-4355	353	4	,	,	PUNCT
american_scientific_journal-4355	353	5	and	and	CCONJ
american_scientific_journal-4355	353	6	weinberg	weinberg	PROPN
american_scientific_journal-4355	353	7	r.a	r.a	PROPN
american_scientific_journal-4355	353	8	.	.	PROPN
american_scientific_journal-4355	353	9	(	(	PUNCT
american_scientific_journal-4355	353	10	2008	2008	NUM
american_scientific_journal-4355	353	11	)	)	PUNCT
american_scientific_journal-4355	353	12	.	.	PUNCT
american_scientific_journal-4355	354	1	epithelial	epithelial	ADJ
american_scientific_journal-4355	354	2	-	-	PUNCT
american_scientific_journal-4355	354	3	mesenchymal	mesenchymal	NOUN
american_scientific_journal-4355	354	4	transition	transition	NOUN
american_scientific_journal-4355	354	5	:	:	PUNCT
american_scientific_journal-4355	354	6	at	at	ADP
american_scientific_journal-4355	354	7	the	the	DET
american_scientific_journal-4355	354	8	crossroads	crossroad	NOUN
american_scientific_journal-4355	354	9	of	of	ADP
american_scientific_journal-4355	354	10	development	development	NOUN
american_scientific_journal-4355	354	11	and	and	CCONJ
american_scientific_journal-4355	354	12	tumor	tumor	NOUN
american_scientific_journal-4355	354	13	metastasis	metastasis	NOUN
american_scientific_journal-4355	354	14	.	.	PUNCT
american_scientific_journal-4355	355	1	dev	dev	PROPN
american_scientific_journal-4355	355	2	cell	cell	NOUN
american_scientific_journal-4355	355	3	14(6):818	14(6):818	PROPN
american_scientific_journal-4355	355	4	-	-	PUNCT
american_scientific_journal-4355	355	5	829	829	NUM
american_scientific_journal-4355	355	6	.	.	PUNCT
american_scientific_journal-4355	356	1	[	[	X
american_scientific_journal-4355	356	2	13	13	NUM
american_scientific_journal-4355	356	3	]	]	X
american_scientific_journal-4355	356	4	bohle	bohle	ADJ
american_scientific_journal-4355	356	5	a.	a.	NOUN
american_scientific_journal-4355	356	6	,	,	PUNCT
american_scientific_journal-4355	356	7	muller	muller	PROPN
american_scientific_journal-4355	356	8	ga	ga	PROPN
american_scientific_journal-4355	356	9	.	.	PROPN
american_scientific_journal-4355	356	10	,	,	PUNCT
american_scientific_journal-4355	356	11	wehrmann	wehrmann	PROPN
american_scientific_journal-4355	356	12	m.	m.	PROPN
american_scientific_journal-4355	356	13	,	,	PUNCT
american_scientific_journal-4355	356	14	mackensen	mackensen	PROPN
american_scientific_journal-4355	356	15	-	-	PUNCT
american_scientific_journal-4355	356	16	haen	haen	NOUN
american_scientific_journal-4355	356	17	s.	s.	PROPN
american_scientific_journal-4355	356	18	,et	,et	PUNCT
american_scientific_journal-4355	356	19	al	al	PROPN
american_scientific_journal-4355	356	20	.	.	PROPN
american_scientific_journal-4355	356	21	(	(	PUNCT
american_scientific_journal-4355	356	22	1996	1996	NUM
american_scientific_journal-4355	356	23	)	)	PUNCT
american_scientific_journal-4355	356	24	.	.	PUNCT
american_scientific_journal-4355	357	1	pathogenesis	pathogenesis	NOUN
american_scientific_journal-4355	357	2	of	of	ADP
american_scientific_journal-4355	357	3	chronic	chronic	ADJ
american_scientific_journal-4355	357	4	renal	renal	ADJ
american_scientific_journal-4355	357	5	failure	failure	NOUN
american_scientific_journal-4355	357	6	in	in	ADP
american_scientific_journal-4355	357	7	the	the	DET
american_scientific_journal-4355	357	8	primary	primary	ADJ
american_scientific_journal-4355	357	9	glomerulopathies	glomerulopathie	NOUN
american_scientific_journal-4355	357	10	,	,	PUNCT
american_scientific_journal-4355	357	11	renal	renal	ADJ
american_scientific_journal-4355	357	12	vasculopathies	vasculopathie	NOUN
american_scientific_journal-4355	357	13	,	,	PUNCT
american_scientific_journal-4355	357	14	and	and	CCONJ
american_scientific_journal-4355	357	15	chronic	chronic	ADJ
american_scientific_journal-4355	357	16	interstitial	interstitial	ADJ
american_scientific_journal-4355	357	17	nephritides	nephritide	NOUN
american_scientific_journal-4355	357	18	.	.	PUNCT
american_scientific_journal-4355	358	1	kidney	kidney	PROPN
american_scientific_journal-4355	358	2	int	int	PROPN
american_scientific_journal-4355	358	3	,	,	PUNCT
american_scientific_journal-4355	358	4	54	54	NUM
american_scientific_journal-4355	358	5	:	:	PUNCT
american_scientific_journal-4355	358	6	s2	s2	VERB
american_scientific_journal-4355	358	7	-	-	PUNCT
american_scientific_journal-4355	358	8	9	9	NUM
american_scientific_journal-4355	358	9	.	.	PUNCT
american_scientific_journal-4355	359	1	[	[	X
american_scientific_journal-4355	359	2	14	14	NUM
american_scientific_journal-4355	359	3	]	]	X
american_scientific_journal-4355	359	4	kalluri	kalluri	PROPN
american_scientific_journal-4355	359	5	r.	r.	PROPN
american_scientific_journal-4355	359	6	,	,	PUNCT
american_scientific_journal-4355	359	7	neilson	neilson	PROPN
american_scientific_journal-4355	359	8	e.g.	e.g.	ADV
american_scientific_journal-4355	359	9	epithelial	epithelial	ADJ
american_scientific_journal-4355	359	10	-	-	PUNCT
american_scientific_journal-4355	359	11	mesenchymal	mesenchymal	NOUN
american_scientific_journal-4355	359	12	transition	transition	NOUN
american_scientific_journal-4355	359	13	and	and	CCONJ
american_scientific_journal-4355	359	14	its	its	PRON
american_scientific_journal-4355	359	15	implications	implication	NOUN
american_scientific_journal-4355	359	16	for	for	ADP
american_scientific_journal-4355	359	17	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	359	18	.	.	PUNCT
american_scientific_journal-4355	360	1	j.	j.	PROPN
american_scientific_journal-4355	360	2	clin	clin	PROPN
american_scientific_journal-4355	360	3	.	.	PUNCT
american_scientific_journal-4355	361	1	invest	invest	VERB
american_scientific_journal-4355	361	2	.	.	PUNCT
american_scientific_journal-4355	362	1	2003;112:1776–1784	2003;112:1776–1784	NUM
american_scientific_journal-4355	362	2	.	.	PUNCT
american_scientific_journal-4355	363	1	[	[	X
american_scientific_journal-4355	363	2	pmc	pmc	PROPN
american_scientific_journal-4355	363	3	free	free	ADJ
american_scientific_journal-4355	363	4	article	article	NOUN
american_scientific_journal-4355	363	5	]	]	X
american_scientific_journal-4355	364	1	[	[	X
american_scientific_journal-4355	364	2	pubmed	pubmed	X
american_scientific_journal-4355	364	3	]	]	X
american_scientific_journal-4355	365	1	[	[	X
american_scientific_journal-4355	365	2	15	15	NUM
american_scientific_journal-4355	365	3	]	]	X
american_scientific_journal-4355	365	4	zavadil	zavadil	PROPN
american_scientific_journal-4355	365	5	j.	j.	PROPN
american_scientific_journal-4355	365	6	,	,	PUNCT
american_scientific_journal-4355	365	7	bottinger	bottinger	PROPN
american_scientific_journal-4355	365	8	e.p	e.p	PROPN
american_scientific_journal-4355	365	9	.	.	PROPN
american_scientific_journal-4355	365	10	tgf	tgf	PROPN
american_scientific_journal-4355	365	11	-	-	PUNCT
american_scientific_journal-4355	365	12	beta	beta	NOUN
american_scientific_journal-4355	365	13	and	and	CCONJ
american_scientific_journal-4355	365	14	epithelial	epithelial	ADJ
american_scientific_journal-4355	365	15	-	-	PUNCT
american_scientific_journal-4355	365	16	to	to	ADP
american_scientific_journal-4355	365	17	-	-	PUNCT
american_scientific_journal-4355	365	18	mesenchymal	mesenchymal	ADJ
american_scientific_journal-4355	365	19	transitions	transition	NOUN
american_scientific_journal-4355	365	20	.	.	PUNCT
american_scientific_journal-4355	366	1	oncogene	oncogene	NOUN
american_scientific_journal-4355	366	2	.	.	PUNCT
american_scientific_journal-4355	367	1	2005;24:5764–5774	2005;24:5764–5774	NUM
american_scientific_journal-4355	367	2	.	.	PUNCT
american_scientific_journal-4355	368	1	doi	doi	PROPN
american_scientific_journal-4355	368	2	:	:	PUNCT
american_scientific_journal-4355	368	3	10.1038	10.1038	NUM
american_scientific_journal-4355	368	4	/	/	SYM
american_scientific_journal-4355	368	5	sj.onc.1208927	sj.onc.1208927	NOUN
american_scientific_journal-4355	368	6	.	.	PUNCT
american_scientific_journal-4355	369	1	[	[	X
american_scientific_journal-4355	369	2	pubmed	pubmed	X
american_scientific_journal-4355	369	3	]	]	X
american_scientific_journal-4355	370	1	[	[	X
american_scientific_journal-4355	370	2	cross	cross	NOUN
american_scientific_journal-4355	370	3	ref	ref	NOUN
american_scientific_journal-4355	370	4	]	]	X
american_scientific_journal-4355	370	5	.	.	PUNCT
american_scientific_journal-4355	371	1	[	[	X
american_scientific_journal-4355	371	2	16	16	NUM
american_scientific_journal-4355	371	3	]	]	X
american_scientific_journal-4355	371	4	vernon	vernon	PROPN
american_scientific_journal-4355	371	5	a.	a.	PROPN
american_scientific_journal-4355	371	6	,	,	PUNCT
american_scientific_journal-4355	371	7	and	and	CCONJ
american_scientific_journal-4355	371	8	labonne	labonne	VERB
american_scientific_journal-4355	371	9	c.	c.	PROPN
american_scientific_journal-4355	371	10	(	(	PUNCT
american_scientific_journal-4355	371	11	2004	2004	NUM
american_scientific_journal-4355	371	12	)	)	PUNCT
american_scientific_journal-4355	371	13	.	.	PUNCT
american_scientific_journal-4355	372	1	tumor	tumor	NOUN
american_scientific_journal-4355	372	2	metastasis	metastasis	NOUN
american_scientific_journal-4355	372	3	:	:	PUNCT
american_scientific_journal-4355	372	4	a	a	DET
american_scientific_journal-4355	372	5	new	new	ADJ
american_scientific_journal-4355	372	6	twist	twist	NOUN
american_scientific_journal-4355	372	7	on	on	ADP
american_scientific_journal-4355	372	8	epithelial	epithelial	ADJ
american_scientific_journal-4355	372	9	-	-	PUNCT
american_scientific_journal-4355	372	10	mesenchymal	mesenchymal	ADJ
american_scientific_journal-4355	372	11	transitions	transition	NOUN
american_scientific_journal-4355	372	12	.	.	PUNCT
american_scientific_journal-4355	373	1	current	current	ADJ
american_scientific_journal-4355	373	2	biology	biology	NOUN
american_scientific_journal-4355	373	3	14	14	NUM
american_scientific_journal-4355	373	4	:	:	PUNCT
american_scientific_journal-4355	373	5	719–21	719–21	X
american_scientific_journal-4355	373	6	.	.	PUNCT
american_scientific_journal-4355	374	1	[	[	X
american_scientific_journal-4355	374	2	17	17	NUM
american_scientific_journal-4355	374	3	]	]	X
american_scientific_journal-4355	374	4	hay	hay	PROPN
american_scientific_journal-4355	374	5	e.d	e.d	PROPN
american_scientific_journal-4355	374	6	.	.	PROPN
american_scientific_journal-4355	374	7	,	,	PUNCT
american_scientific_journal-4355	374	8	and	and	CCONJ
american_scientific_journal-4355	374	9	zuk	zuk	PROPN
american_scientific_journal-4355	374	10	a.	a.	PROPN
american_scientific_journal-4355	374	11	(	(	PUNCT
american_scientific_journal-4355	374	12	1995	1995	NUM
american_scientific_journal-4355	374	13	)	)	PUNCT
american_scientific_journal-4355	374	14	.	.	PUNCT
american_scientific_journal-4355	375	1	transformations	transformation	NOUN
american_scientific_journal-4355	375	2	between	between	ADP
american_scientific_journal-4355	375	3	epithelium	epithelium	NOUN
american_scientific_journal-4355	375	4	and	and	CCONJ
american_scientific_journal-4355	375	5	mesenchyme	mesenchyme	NOUN
american_scientific_journal-4355	375	6	:	:	PUNCT
american_scientific_journal-4355	375	7	normal	normal	ADJ
american_scientific_journal-4355	375	8	,	,	PUNCT
american_scientific_journal-4355	375	9	pathological	pathological	ADJ
american_scientific_journal-4355	375	10	,	,	PUNCT
american_scientific_journal-4355	375	11	and	and	CCONJ
american_scientific_journal-4355	375	12	experimentally	experimentally	ADV
american_scientific_journal-4355	375	13	induced	induce	VERB
american_scientific_journal-4355	375	14	.	.	PUNCT
american_scientific_journal-4355	376	1	am	be	AUX
american_scientific_journal-4355	376	2	j	j	PROPN
american_scientific_journal-4355	376	3	kidney	kidney	PROPN
american_scientific_journal-4355	376	4	dis	dis	PROPN
american_scientific_journal-4355	376	5	,	,	PUNCT
american_scientific_journal-4355	376	6	26(4):678	26(4):678	PROPN
american_scientific_journal-4355	376	7	-	-	PUNCT
american_scientific_journal-4355	376	8	690	690	NUM
american_scientific_journal-4355	376	9	.	.	PUNCT
american_scientific_journal-4355	377	1	[	[	X
american_scientific_journal-4355	377	2	18	18	NUM
american_scientific_journal-4355	377	3	]	]	X
american_scientific_journal-4355	377	4	lopez	lopez	PROPN
american_scientific_journal-4355	377	5	-	-	PUNCT
american_scientific_journal-4355	377	6	casillas	casillas	PROPN
american_scientific_journal-4355	377	7	f.	f.	PROPN
american_scientific_journal-4355	377	8	,	,	PUNCT
american_scientific_journal-4355	377	9	wrana	wrana	PROPN
american_scientific_journal-4355	377	10	j.l	j.l	PROPN
american_scientific_journal-4355	377	11	.	.	PROPN
american_scientific_journal-4355	377	12	,	,	PUNCT
american_scientific_journal-4355	377	13	massague	massague	PROPN
american_scientific_journal-4355	377	14	j.	j.	PROPN
american_scientific_journal-4355	377	15	(	(	PUNCT
american_scientific_journal-4355	377	16	1993	1993	NUM
american_scientific_journal-4355	377	17	)	)	PUNCT
american_scientific_journal-4355	377	18	.	.	PUNCT
american_scientific_journal-4355	378	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	378	2	presents	present	VERB
american_scientific_journal-4355	378	3	ligand	ligand	VERB
american_scientific_journal-4355	378	4	to	to	ADP
american_scientific_journal-4355	378	5	the	the	DET
american_scientific_journal-4355	378	6	tgfβ	tgfβ	ADJ
american_scientific_journal-4355	378	7	signalingreceptor	signalingreceptor	NOUN
american_scientific_journal-4355	378	8	.	.	PUNCT
american_scientific_journal-4355	379	1	cell	cell	NOUN
american_scientific_journal-4355	379	2	73	73	NUM
american_scientific_journal-4355	379	3	:	:	PUNCT
american_scientific_journal-4355	379	4	1435	1435	NUM
american_scientific_journal-4355	379	5	-	-	SYM
american_scientific_journal-4355	379	6	1444	1444	NUM
american_scientific_journal-4355	379	7	.	.	PUNCT
american_scientific_journal-4355	380	1	[	[	X
american_scientific_journal-4355	380	2	19	19	NUM
american_scientific_journal-4355	380	3	]	]	X
american_scientific_journal-4355	380	4	andres	andres	PROPN
american_scientific_journal-4355	380	5	j.l	j.l	PROPN
american_scientific_journal-4355	380	6	.	.	PROPN
american_scientific_journal-4355	380	7	,	,	PUNCT
american_scientific_journal-4355	380	8	defalcis	defalcis	PROPN
american_scientific_journal-4355	380	9	d.	d.	PROPN
american_scientific_journal-4355	380	10	,	,	PUNCT
american_scientific_journal-4355	380	11	et	et	PROPN
american_scientific_journal-4355	380	12	al	al	PROPN
american_scientific_journal-4355	380	13	.	.	PROPN
american_scientific_journal-4355	381	1	(	(	PUNCT
american_scientific_journal-4355	381	2	1992	1992	NUM
american_scientific_journal-4355	381	3	)	)	PUNCT
american_scientific_journal-4355	381	4	.	.	PUNCT
american_scientific_journal-4355	382	1	binding	bind	VERB
american_scientific_journal-4355	382	2	of	of	ADP
american_scientific_journal-4355	382	3	two	two	NUM
american_scientific_journal-4355	382	4	growth	growth	NOUN
american_scientific_journal-4355	382	5	factor	factor	NOUN
american_scientific_journal-4355	382	6	families	family	NOUN
american_scientific_journal-4355	382	7	to	to	ADP
american_scientific_journal-4355	382	8	separate	separate	ADJ
american_scientific_journal-4355	382	9	domains	domain	NOUN
american_scientific_journal-4355	382	10	of	of	ADP
american_scientific_journal-4355	382	11	the	the	DET
american_scientific_journal-4355	382	12	proteoglycan	proteoglycan	ADJ
american_scientific_journal-4355	382	13	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	382	14	.	.	PUNCT
american_scientific_journal-4355	383	1	j.	j.	PROPN
american_scientific_journal-4355	383	2	biol	biol	PROPN
american_scientific_journal-4355	383	3	.	.	PUNCT
american_scientific_journal-4355	384	1	chem	chem	PROPN
american_scientific_journal-4355	384	2	,	,	PUNCT
american_scientific_journal-4355	384	3	267(9):5927	267(9):5927	PROPN
american_scientific_journal-4355	384	4	-	-	NOUN
american_scientific_journal-4355	384	5	5930	5930	NUM
american_scientific_journal-4355	384	6	.	.	PUNCT
american_scientific_journal-4355	385	1	[	[	X
american_scientific_journal-4355	385	2	20	20	NUM
american_scientific_journal-4355	385	3	]	]	X
american_scientific_journal-4355	385	4	lopez	lopez	PROPN
american_scientific_journal-4355	385	5	-	-	PUNCT
american_scientific_journal-4355	385	6	casillas	casillas	PROPN
american_scientific_journal-4355	385	7	f.	f.	PROPN
american_scientific_journal-4355	385	8	,	,	PUNCT
american_scientific_journal-4355	385	9	wrana	wrana	PROPN
american_scientific_journal-4355	385	10	j.l	j.l	PROPN
american_scientific_journal-4355	385	11	.	.	PROPN
american_scientific_journal-4355	385	12	,	,	PUNCT
american_scientific_journal-4355	385	13	massague	massague	PROPN
american_scientific_journal-4355	385	14	j.	j.	PROPN
american_scientific_journal-4355	385	15	(	(	PUNCT
american_scientific_journal-4355	385	16	1993	1993	NUM
american_scientific_journal-4355	385	17	)	)	PUNCT
american_scientific_journal-4355	385	18	.	.	PUNCT
american_scientific_journal-4355	386	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	386	2	presents	present	VERB
american_scientific_journal-4355	386	3	ligand	ligand	VERB
american_scientific_journal-4355	386	4	to	to	ADP
american_scientific_journal-4355	386	5	the	the	DET
american_scientific_journal-4355	386	6	tgfβ	tgfβ	ADJ
american_scientific_journal-4355	386	7	signaling	signal	VERB
american_scientific_journal-4355	386	8	receptor	receptor	NOUN
american_scientific_journal-4355	386	9	.	.	PUNCT
american_scientific_journal-4355	387	1	cell	cell	NOUN
american_scientific_journal-4355	387	2	73	73	NUM
american_scientific_journal-4355	387	3	:	:	PUNCT
american_scientific_journal-4355	387	4	1435	1435	NUM
american_scientific_journal-4355	387	5	-	-	SYM
american_scientific_journal-4355	387	6	1444	1444	NUM
american_scientific_journal-4355	387	7	.	.	PUNCT
american_scientific_journal-4355	388	1	[	[	X
american_scientific_journal-4355	388	2	21	21	NUM
american_scientific_journal-4355	388	3	]	]	PUNCT
american_scientific_journal-4355	388	4	sergarini	sergarini	NOUN
american_scientific_journal-4355	388	5	,	,	PUNCT
american_scientific_journal-4355	388	6	p.	p.	PROPN
american_scientific_journal-4355	388	7	r.	r.	PROPN
american_scientific_journal-4355	388	8	and	and	CCONJ
american_scientific_journal-4355	388	9	seyedin	seyedin	PROPN
american_scientific_journal-4355	388	10	,	,	PUNCT
american_scientific_journal-4355	388	11	s.	s.	PROPN
american_scientific_journal-4355	388	12	m.	m.	PROPN
american_scientific_journal-4355	388	13	(	(	PUNCT
american_scientific_journal-4355	388	14	1988	1988	NUM
american_scientific_journal-4355	388	15	)	)	PUNCT
american_scientific_journal-4355	388	16	j.	j.	PROPN
american_scientific_journal-4355	388	17	biol	biol	PROPN
american_scientific_journal-4355	388	18	.	.	PUNCT
american_scientific_journal-4355	389	1	chem	chem	NOUN
american_scientific_journal-4355	389	2	.	.	PUNCT
american_scientific_journal-4355	390	1	263	263	NUM
american_scientific_journal-4355	390	2	,	,	PUNCT
american_scientific_journal-4355	390	3	8366±837	8366±837	NOUN
american_scientific_journal-4355	390	4	.	.	PUNCT
american_scientific_journal-4355	391	1	[	[	X
american_scientific_journal-4355	391	2	22	22	NUM
american_scientific_journal-4355	391	3	]	]	PUNCT
american_scientific_journal-4355	391	4	bjorklund	bjorklund	NOUN
american_scientific_journal-4355	391	5	m.	m.	NOUN
american_scientific_journal-4355	391	6	,	,	PUNCT
american_scientific_journal-4355	391	7	and	and	CCONJ
american_scientific_journal-4355	391	8	koivunen	koivunen	PROPN
american_scientific_journal-4355	391	9	e.	e.	PROPN
american_scientific_journal-4355	391	10	(	(	PUNCT
american_scientific_journal-4355	391	11	2005	2005	NUM
american_scientific_journal-4355	391	12	)	)	PUNCT
american_scientific_journal-4355	391	13	.	.	PUNCT
american_scientific_journal-4355	392	1	gelatinase	gelatinase	NOUN
american_scientific_journal-4355	392	2	-	-	PUNCT
american_scientific_journal-4355	392	3	mediated	mediate	VERB
american_scientific_journal-4355	392	4	migration	migration	NOUN
american_scientific_journal-4355	392	5	and	and	CCONJ
american_scientific_journal-4355	392	6	invasion	invasion	NOUN
american_scientific_journal-4355	392	7	of	of	ADP
american_scientific_journal-4355	392	8	cancer	cancer	NOUN
american_scientific_journal-4355	392	9	cells	cell	NOUN
american_scientific_journal-4355	392	10	.	.	PUNCT
american_scientific_journal-4355	393	1	biochim	biochim	PROPN
american_scientific_journal-4355	393	2	biophys	biophy	NOUN
american_scientific_journal-4355	393	3	acta	acta	PROPN
american_scientific_journal-4355	393	4	,	,	PUNCT
american_scientific_journal-4355	393	5	1755(1):37	1755(1):37	NUM
american_scientific_journal-4355	393	6	-	-	SYM
american_scientific_journal-4355	393	7	69	69	NUM
american_scientific_journal-4355	393	8	.	.	PUNCT
american_scientific_journal-4355	394	1	[	[	X
american_scientific_journal-4355	394	2	23	23	NUM
american_scientific_journal-4355	394	3	]	]	X
american_scientific_journal-4355	394	4	gallagher	gallagher	PROPN
american_scientific_journal-4355	394	5	j.t	j.t	PROPN
american_scientific_journal-4355	394	6	.	.	PROPN
american_scientific_journal-4355	394	7	,	,	PUNCT
american_scientific_journal-4355	394	8	and	and	CCONJ
american_scientific_journal-4355	394	9	lyon	lyon	PROPN
american_scientific_journal-4355	394	10	m.	m.	PROPN
american_scientific_journal-4355	394	11	(	(	PUNCT
american_scientific_journal-4355	394	12	2000	2000	NUM
american_scientific_journal-4355	394	13	)	)	PUNCT
american_scientific_journal-4355	394	14	.	.	PUNCT
american_scientific_journal-4355	395	1	molecular	molecular	ADJ
american_scientific_journal-4355	395	2	structure	structure	NOUN
american_scientific_journal-4355	395	3	of	of	ADP
american_scientific_journal-4355	395	4	heparan	heparan	ADJ
american_scientific_journal-4355	395	5	sulfate	sulfate	NOUN
american_scientific_journal-4355	395	6	and	and	CCONJ
american_scientific_journal-4355	395	7	interactions	interaction	NOUN
american_scientific_journal-4355	395	8	with	with	ADP
american_scientific_journal-4355	395	9	growth	growth	NOUN
american_scientific_journal-4355	395	10	factors	factor	NOUN
american_scientific_journal-4355	395	11	and	and	CCONJ
american_scientific_journal-4355	395	12	morphogens	morphogen	NOUN
american_scientific_journal-4355	395	13	.	.	PUNCT
american_scientific_journal-4355	396	1	in	in	ADP
american_scientific_journal-4355	396	2	iozzo	iozzo	PROPN
american_scientific_journal-4355	396	3	m.v	m.v	PROPN
american_scientific_journal-4355	396	4	.	.	PUNCT
american_scientific_journal-4355	397	1	(	(	PUNCT
american_scientific_journal-4355	397	2	ed	ed	NOUN
american_scientific_journal-4355	397	3	)	)	PUNCT
american_scientific_journal-4355	397	4	.	.	PUNCT
american_scientific_journal-4355	398	1	proteoglycans	proteoglycan	NOUN
american_scientific_journal-4355	398	2	:	:	PUNCT
american_scientific_journal-4355	398	3	structure	structure	NOUN
american_scientific_journal-4355	398	4	,	,	PUNCT
american_scientific_journal-4355	398	5	biology	biology	NOUN
american_scientific_journal-4355	398	6	and	and	CCONJ
american_scientific_journal-4355	398	7	molecular	molecular	ADJ
american_scientific_journal-4355	398	8	interactions	interaction	NOUN
american_scientific_journal-4355	398	9	.	.	PUNCT
american_scientific_journal-4355	399	1	new	new	PROPN
american_scientific_journal-4355	399	2	york	york	PROPN
american_scientific_journal-4355	399	3	.	.	PUNCT
american_scientific_journal-4355	400	1	marcel	marcel	PROPN
american_scientific_journal-4355	400	2	dekker	dekker	PROPN
american_scientific_journal-4355	400	3	inc	inc	PROPN
american_scientific_journal-4355	400	4	.	.	PROPN
american_scientific_journal-4355	401	1	pp	pp	PROPN
american_scientific_journal-4355	401	2	.	.	PUNCT
american_scientific_journal-4355	402	1	27	27	NUM
american_scientific_journal-4355	402	2	-	-	SYM
american_scientific_journal-4355	402	3	59	59	NUM
american_scientific_journal-4355	402	4	.	.	PUNCT
american_scientific_journal-4355	403	1	[	[	X
american_scientific_journal-4355	403	2	24	24	NUM
american_scientific_journal-4355	403	3	]	]	X
american_scientific_journal-4355	403	4	vilchis	vilchis	ADJ
american_scientific_journal-4355	403	5	-	-	PUNCT
american_scientific_journal-4355	403	6	landeros	landero	NOUN
american_scientific_journal-4355	403	7	m.m	m.m	PROPN
american_scientific_journal-4355	403	8	.	.	PROPN
american_scientific_journal-4355	403	9	,	,	PUNCT
american_scientific_journal-4355	403	10	montiel	montiel	PROPN
american_scientific_journal-4355	403	11	jl	jl	PROPN
american_scientific_journal-4355	403	12	.	.	PROPN
american_scientific_journal-4355	403	13	,	,	PUNCT
american_scientific_journal-4355	403	14	mendoza	mendoza	PROPN
american_scientific_journal-4355	403	15	v.	v.	PROPN
american_scientific_journal-4355	403	16	,	,	PUNCT
american_scientific_journal-4355	403	17	mendoza	mendoza	PROPN
american_scientific_journal-4355	403	18	-	-	PUNCT
american_scientific_journal-4355	403	19	hernández	hernández	PROPN
american_scientific_journal-4355	403	20	g.	g.	PROPN
american_scientific_journal-4355	403	21	,et	,et	PUNCT
american_scientific_journal-4355	403	22	al	al	PROPN
american_scientific_journal-4355	403	23	.	.	PUNCT
american_scientific_journal-4355	404	1	(	(	PUNCT
american_scientific_journal-4355	404	2	2001	2001	NUM
american_scientific_journal-4355	404	3	)	)	PUNCT
american_scientific_journal-4355	404	4	.	.	PUNCT
american_scientific_journal-4355	405	1	f.	f.	PROPN
american_scientific_journal-4355	405	2	recombinant	recombinant	ADJ
american_scientific_journal-4355	405	3	soluble	soluble	ADJ
american_scientific_journal-4355	405	4	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	405	5	is	be	AUX
american_scientific_journal-4355	405	6	a	a	DET
american_scientific_journal-4355	405	7	potent	potent	ADJ
american_scientific_journal-4355	405	8	and	and	CCONJ
american_scientific_journal-4355	405	9	isoform	isoform	NOUN
american_scientific_journal-4355	405	10	-	-	PUNCT
american_scientific_journal-4355	405	11	selective	selective	ADJ
american_scientific_journal-4355	405	12	transforming	transform	VERB
american_scientific_journal-4355	405	13	growth	growth	NOUN
american_scientific_journal-4355	405	14	factor	factor	NOUN
american_scientific_journal-4355	405	15	neutralizing	neutralize	VERB
american_scientific_journal-4355	405	16	agent	agent	NOUN
american_scientific_journal-4355	405	17	.	.	PUNCT
american_scientific_journal-4355	406	1	biochem	biochem	PROPN
american_scientific_journal-4355	406	2	j	j	PROPN
american_scientific_journal-4355	406	3	355	355	NUM
american_scientific_journal-4355	406	4	:	:	PUNCT
american_scientific_journal-4355	406	5	215–222	215–222	NUM
american_scientific_journal-4355	406	6	.	.	PUNCT
american_scientific_journal-4355	407	1	[	[	X
american_scientific_journal-4355	407	2	25	25	NUM
american_scientific_journal-4355	407	3	]	]	X
american_scientific_journal-4355	407	4	andres	andres	PROPN
american_scientific_journal-4355	407	5	j.l	j.l	PROPN
american_scientific_journal-4355	407	6	.	.	PROPN
american_scientific_journal-4355	407	7	,	,	PUNCT
american_scientific_journal-4355	407	8	defalcis	defalcis	PROPN
american_scientific_journal-4355	407	9	d.	d.	PROPN
american_scientific_journal-4355	407	10	,	,	PUNCT
american_scientific_journal-4355	407	11	et	et	PROPN
american_scientific_journal-4355	407	12	al	al	PROPN
american_scientific_journal-4355	407	13	.	.	PROPN
american_scientific_journal-4355	408	1	(	(	PUNCT
american_scientific_journal-4355	408	2	1992	1992	NUM
american_scientific_journal-4355	408	3	)	)	PUNCT
american_scientific_journal-4355	408	4	.	.	PUNCT
american_scientific_journal-4355	409	1	binding	bind	VERB
american_scientific_journal-4355	409	2	of	of	ADP
american_scientific_journal-4355	409	3	two	two	NUM
american_scientific_journal-4355	409	4	growth	growth	NOUN
american_scientific_journal-4355	409	5	factor	factor	NOUN
american_scientific_journal-4355	409	6	families	family	NOUN
american_scientific_journal-4355	409	7	to	to	ADP
american_scientific_journal-4355	409	8	separate	separate	ADJ
american_scientific_journal-4355	409	9	domains	domain	NOUN
american_scientific_journal-4355	409	10	of	of	ADP
american_scientific_journal-4355	409	11	the	the	DET
american_scientific_journal-4355	409	12	proteoglycan	proteoglycan	ADJ
american_scientific_journal-4355	409	13	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	409	14	.	.	PUNCT
american_scientific_journal-4355	410	1	j.	j.	PROPN
american_scientific_journal-4355	410	2	biol	biol	PROPN
american_scientific_journal-4355	410	3	.	.	PUNCT
american_scientific_journal-4355	411	1	chem	chem	PROPN
american_scientific_journal-4355	411	2	,	,	PUNCT
american_scientific_journal-4355	411	3	267(9):5927	267(9):5927	PROPN
american_scientific_journal-4355	411	4	-	-	NOUN
american_scientific_journal-4355	411	5	5930	5930	NUM
american_scientific_journal-4355	411	6	.	.	PUNCT
american_scientific_journal-4355	412	1	[	[	X
american_scientific_journal-4355	412	2	26	26	NUM
american_scientific_journal-4355	412	3	]	]	X
american_scientific_journal-4355	412	4	cohen	cohen	PROPN
american_scientific_journal-4355	412	5	,	,	PUNCT
american_scientific_journal-4355	412	6	m.p	m.p	PROPN
american_scientific_journal-4355	412	7	.	.	PROPN
american_scientific_journal-4355	412	8	,	,	PUNCT
american_scientific_journal-4355	412	9	sharma	sharma	PROPN
american_scientific_journal-4355	412	10	k.	k.	PROPN
american_scientific_journal-4355	412	11	,	,	PUNCT
american_scientific_journal-4355	412	12	jin	jin	PROPN
american_scientific_journal-4355	412	13	y.	y.	PROPN
american_scientific_journal-4355	412	14	,	,	PUNCT
american_scientific_journal-4355	412	15	hud	hud	PROPN
american_scientific_journal-4355	412	16	e.	e.	PROPN
american_scientific_journal-4355	412	17	,	,	PUNCT
american_scientific_journal-4355	412	18	et	et	PROPN
american_scientific_journal-4355	412	19	al	al	PROPN
american_scientific_journal-4355	412	20	.	.	PROPN
american_scientific_journal-4355	412	21	(	(	PUNCT
american_scientific_journal-4355	412	22	1995	1995	NUM
american_scientific_journal-4355	412	23	)	)	PUNCT
american_scientific_journal-4355	412	24	.	.	PUNCT
american_scientific_journal-4355	413	1	prevention	prevention	NOUN
american_scientific_journal-4355	413	2	of	of	ADP
american_scientific_journal-4355	413	3	diabetic	diabetic	ADJ
american_scientific_journal-4355	413	4	nephropathy	nephropathy	NOUN
american_scientific_journal-4355	413	5	in	in	ADP
american_scientific_journal-4355	413	6	db	db	PROPN
american_scientific_journal-4355	413	7	/	/	SYM
american_scientific_journal-4355	413	8	db	db	PROPN
american_scientific_journal-4355	413	9	mice	mouse	NOUN
american_scientific_journal-4355	413	10	with	with	ADP
american_scientific_journal-4355	413	11	glycanated	glycanate	VERB
american_scientific_journal-4355	413	12	albumin	albumin	ADJ
american_scientific_journal-4355	413	13	antagonists	antagonist	NOUN
american_scientific_journal-4355	413	14	:	:	PUNCT
american_scientific_journal-4355	413	15	a	a	DET
american_scientific_journal-4355	413	16	novel	novel	ADJ
american_scientific_journal-4355	413	17	treatment	treatment	NOUN
american_scientific_journal-4355	413	18	strategy	strategy	NOUN
american_scientific_journal-4355	413	19	.	.	PUNCT
american_scientific_journal-4355	414	1	j	j	PROPN
american_scientific_journal-4355	414	2	clin	clin	PROPN
american_scientific_journal-4355	414	3	invest	invest	VERB
american_scientific_journal-4355	414	4	95	95	NUM
american_scientific_journal-4355	414	5	:	:	PUNCT
american_scientific_journal-4355	414	6	2338	2338	NUM
american_scientific_journal-4355	414	7	-	-	SYM
american_scientific_journal-4355	414	8	2345	2345	NUM
american_scientific_journal-4355	414	9	.	.	PUNCT
american_scientific_journal-4355	415	1	[	[	X
american_scientific_journal-4355	415	2	27	27	NUM
american_scientific_journal-4355	415	3	]	]	X
american_scientific_journal-4355	415	4	juárez	juárez	NOUN
american_scientific_journal-4355	415	5	p.	p.	PROPN
american_scientific_journal-4355	415	6	,	,	PUNCT
american_scientific_journal-4355	415	7	vilchis	vilchis	ADJ
american_scientific_journal-4355	415	8	-	-	PUNCT
american_scientific_journal-4355	415	9	landeros	landero	NOUN
american_scientific_journal-4355	415	10	m.m	m.m	PROPN
american_scientific_journal-4355	415	11	.	.	PROPN
american_scientific_journal-4355	415	12	,	,	PUNCT
american_scientific_journal-4355	415	13	ponce	ponce	PROPN
american_scientific_journal-4355	415	14	-	-	PUNCT
american_scientific_journal-4355	415	15	coria	coria	PROPN
american_scientific_journal-4355	415	16	j.	j.	PROPN
american_scientific_journal-4355	415	17	,	,	PUNCT
american_scientific_journal-4355	415	18	mendoza	mendoza	PROPN
american_scientific_journal-4355	415	19	v.	v.	PROPN
american_scientific_journal-4355	415	20	,	,	PUNCT
american_scientific_journal-4355	415	21	et	et	PROPN
american_scientific_journal-4355	415	22	al	al	PROPN
american_scientific_journal-4355	415	23	(	(	PUNCT
american_scientific_journal-4355	415	24	2006	2006	NUM
american_scientific_journal-4355	415	25	)	)	PUNCT
american_scientific_journal-4355	415	26	,	,	PUNCT
american_scientific_journal-4355	415	27	(	(	PUNCT
american_scientific_journal-4355	415	28	soluble	soluble	ADJ
american_scientific_journal-4355	415	29	betaglycanreduces	betaglycanreduce	NOUN
american_scientific_journal-4355	415	30	renal	renal	ADJ
american_scientific_journal-4355	415	31	damage	damage	NOUN
american_scientific_journal-4355	415	32	progression	progression	NOUN
american_scientific_journal-4355	415	33	in	in	ADP
american_scientific_journal-4355	415	34	db	db	PROPN
american_scientific_journal-4355	415	35	/	/	SYM
american_scientific_journal-4355	415	36	db	db	PROPN
american_scientific_journal-4355	415	37	mice).am	mice).am	NOUN
american_scientific_journal-4355	415	38	j	j	PROPN
american_scientific_journal-4355	415	39	physiol	physiol	PROPN
american_scientific_journal-4355	415	40	renal	renal	PROPN
american_scientific_journal-4355	415	41	physiol	physiol	PROPN
american_scientific_journal-4355	415	42	292	292	NUM
american_scientific_journal-4355	415	43	:	:	PUNCT
american_scientific_journal-4355	415	44	f321	f321	NOUN
american_scientific_journal-4355	415	45	-	-	PUNCT
american_scientific_journal-4355	415	46	f32	f32	NOUN
american_scientific_journal-4355	415	47	.	.	PUNCT
american_scientific_journal-4355	416	1	[	[	X
american_scientific_journal-4355	416	2	28	28	NUM
american_scientific_journal-4355	416	3	]	]	X
american_scientific_journal-4355	416	4	lópez	lópez	PROPN
american_scientific_journal-4355	416	5	-	-	PUNCT
american_scientific_journal-4355	416	6	casillas	casillas	PROPN
american_scientific_journal-4355	416	7	f.	f.	PROPN
american_scientific_journal-4355	416	8	,	,	PUNCT
american_scientific_journal-4355	416	9	payne	payne	PROPN
american_scientific_journal-4355	416	10	h.m	h.m	PROPN
american_scientific_journal-4355	416	11	.	.	PROPN
american_scientific_journal-4355	416	12	,	,	PUNCT
american_scientific_journal-4355	416	13	andres	andres	PROPN
american_scientific_journal-4355	416	14	j.l	j.l	PROPN
american_scientific_journal-4355	416	15	.	.	PROPN
american_scientific_journal-4355	416	16	,	,	PUNCT
american_scientific_journal-4355	416	17	massague	massague	PROPN
american_scientific_journal-4355	416	18	j.	j.	PROPN
american_scientific_journal-4355	416	19	(	(	PUNCT
american_scientific_journal-4355	416	20	1994	1994	NUM
american_scientific_journal-4355	416	21	)	)	PUNCT
american_scientific_journal-4355	416	22	.	.	PUNCT
american_scientific_journal-4355	417	1	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	417	2	can	can	AUX
american_scientific_journal-4355	417	3	act	act	VERB
american_scientific_journal-4355	417	4	as	as	ADP
american_scientific_journal-4355	417	5	a	a	DET
american_scientific_journal-4355	417	6	dual	dual	ADJ
american_scientific_journal-4355	417	7	modulator	modulator	NOUN
american_scientific_journal-4355	417	8	of	of	ADP
american_scientific_journal-4355	417	9	tgf	tgf	PROPN
american_scientific_journal-4355	417	10	-	-	PUNCT
american_scientific_journal-4355	417	11	β	β	NOUN
american_scientific_journal-4355	417	12	access	access	NOUN
american_scientific_journal-4355	417	13	to	to	ADP
american_scientific_journal-4355	417	14	signaling	signal	VERB
american_scientific_journal-4355	417	15	receptors	receptor	NOUN
american_scientific_journal-4355	417	16	:	:	PUNCT
american_scientific_journal-4355	417	17	mapping	mapping	NOUN
american_scientific_journal-4355	417	18	of	of	ADP
american_scientific_journal-4355	417	19	ligand	ligand	ADJ
american_scientific_journal-4355	417	20	binding	bind	VERB
american_scientific_journal-4355	417	21	and	and	CCONJ
american_scientific_journal-4355	417	22	gag	gag	NOUN
american_scientific_journal-4355	417	23	attachment	attachment	NOUN
american_scientific_journal-4355	417	24	sites	site	NOUN
american_scientific_journal-4355	417	25	.	.	PUNCT
american_scientific_journal-4355	418	1	j	j	PROPN
american_scientific_journal-4355	418	2	cell	cell	NOUN
american_scientific_journal-4355	418	3	biol	biol	NOUN
american_scientific_journal-4355	418	4	124	124	NUM
american_scientific_journal-4355	418	5	:	:	PUNCT
american_scientific_journal-4355	418	6	557	557	NUM
american_scientific_journal-4355	418	7	-	-	SYM
american_scientific_journal-4355	418	8	568	568	NUM
american_scientific_journal-4355	418	9	.	.	PUNCT
american_scientific_journal-4355	419	1	[	[	X
american_scientific_journal-4355	419	2	29	29	NUM
american_scientific_journal-4355	419	3	]	]	X
american_scientific_journal-4355	419	4	velasco	velasco	PROPN
american_scientific_journal-4355	419	5	-	-	PUNCT
american_scientific_journal-4355	419	6	loyden	loyden	PROPN
american_scientific_journal-4355	419	7	g.	g.	NOUN
american_scientific_journal-4355	419	8	,	,	PUNCT
american_scientific_journal-4355	419	9	arribas	arribas	PROPN
american_scientific_journal-4355	419	10	j.	j.	PROPN
american_scientific_journal-4355	419	11	,	,	PUNCT
american_scientific_journal-4355	419	12	and	and	CCONJ
american_scientific_journal-4355	419	13	lópez	lópez	PROPN
american_scientific_journal-4355	419	14	-	-	PUNCT
american_scientific_journal-4355	419	15	casillas	casillas	PROPN
american_scientific_journal-4355	419	16	f.	f.	PROPN
american_scientific_journal-4355	419	17	(	(	PUNCT
american_scientific_journal-4355	419	18	2004	2004	NUM
american_scientific_journal-4355	419	19	)	)	PUNCT
american_scientific_journal-4355	419	20	.	.	PUNCT
american_scientific_journal-4355	420	1	the	the	DET
american_scientific_journal-4355	420	2	shedding	shedding	NOUN
american_scientific_journal-4355	420	3	of	of	ADP
american_scientific_journal-4355	420	4	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	420	5	is	be	AUX
american_scientific_journal-4355	420	6	regulated	regulate	VERB
american_scientific_journal-4355	420	7	by	by	ADP
american_scientific_journal-4355	420	8	pervanadate	pervanadate	NOUN
american_scientific_journal-4355	420	9	and	and	CCONJ
american_scientific_journal-4355	420	10	mediated	mediate	VERB
american_scientific_journal-4355	420	11	by	by	ADP
american_scientific_journal-4355	420	12	membrane	membrane	NOUN
american_scientific_journal-4355	420	13	type	type	NOUN
american_scientific_journal-4355	420	14	matrix	matrix	NOUN
american_scientific_journal-4355	420	15	metalloprotease-1	metalloprotease-1	NOUN
american_scientific_journal-4355	420	16	.	.	PUNCT
american_scientific_journal-4355	421	1	j	j	PROPN
american_scientific_journal-4355	421	2	biol	biol	PROPN
american_scientific_journal-4355	421	3	chem	chem	NOUN
american_scientific_journal-4355	421	4	279	279	NUM
american_scientific_journal-4355	421	5	:	:	PUNCT
american_scientific_journal-4355	421	6	77217733	77217733	NUM
american_scientific_journal-4355	421	7	.	.	PUNCT
american_scientific_journal-4355	422	1	[	[	X
american_scientific_journal-4355	422	2	30	30	NUM
american_scientific_journal-4355	422	3	]	]	X
american_scientific_journal-4355	422	4	juárez	juárez	NOUN
american_scientific_journal-4355	422	5	p.	p.	PROPN
american_scientific_journal-4355	422	6	,	,	PUNCT
american_scientific_journal-4355	422	7	vilchis	vilchis	ADJ
american_scientific_journal-4355	422	8	-	-	PUNCT
american_scientific_journal-4355	422	9	landeros	landero	NOUN
american_scientific_journal-4355	422	10	,	,	PUNCT
american_scientific_journal-4355	422	11	ponce	ponce	PROPN
american_scientific_journal-4355	422	12	-	-	PUNCT
american_scientific_journal-4355	422	13	coria	coria	PROPN
american_scientific_journal-4355	422	14	j.	j.	PROPN
american_scientific_journal-4355	422	15	and	and	CCONJ
american_scientific_journal-4355	422	16	lópez	lópez	PROPN
american_scientific_journal-4355	422	17	-	-	PUNCT
american_scientific_journal-4355	422	18	casillas	casillas	PROPN
american_scientific_journal-4355	422	19	f.	f.	PROPN
american_scientific_journal-4355	422	20	(	(	PUNCT
american_scientific_journal-4355	422	21	2006	2006	NUM
american_scientific_journal-4355	422	22	)	)	PUNCT
american_scientific_journal-4355	422	23	,	,	PUNCT
american_scientific_journal-4355	422	24	(	(	PUNCT
american_scientific_journal-4355	422	25	soluble	soluble	ADJ
american_scientific_journal-4355	422	26	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	422	27	reduces	reduce	VERB
american_scientific_journal-4355	422	28	renal	renal	ADJ
american_scientific_journal-4355	422	29	damage	damage	NOUN
american_scientific_journal-4355	422	30	progression	progression	NOUN
american_scientific_journal-4355	422	31	in	in	ADP
american_scientific_journal-4355	422	32	db	db	PROPN
american_scientific_journal-4355	422	33	/	/	SYM
american_scientific_journal-4355	422	34	db	db	PROPN
american_scientific_journal-4355	422	35	mice	mouse	NOUN
american_scientific_journal-4355	422	36	)	)	PUNCT
american_scientific_journal-4355	422	37	.	.	PUNCT
american_scientific_journal-4355	423	1	am	be	AUX
american_scientific_journal-4355	423	2	j	j	PROPN
american_scientific_journal-4355	423	3	physiol	physiol	PROPN
american_scientific_journal-4355	423	4	renal	renal	PROPN
american_scientific_journal-4355	423	5	physiol	physiol	PROPN
american_scientific_journal-4355	423	6	292	292	NUM
american_scientific_journal-4355	423	7	:	:	PUNCT
american_scientific_journal-4355	423	8	f321	f321	NOUN
american_scientific_journal-4355	423	9	-	-	PUNCT
american_scientific_journal-4355	423	10	f32	f32	NOUN
american_scientific_journal-4355	423	11	.	.	PUNCT
american_scientific_journal-4355	424	1	[	[	X
american_scientific_journal-4355	424	2	31	31	NUM
american_scientific_journal-4355	424	3	]	]	X
american_scientific_journal-4355	424	4	crisan	crisan	NOUN
american_scientific_journal-4355	424	5	m	m	PROPN
american_scientific_journal-4355	424	6	,	,	PUNCT
american_scientific_journal-4355	424	7	yap	yap	PROPN
american_scientific_journal-4355	424	8	s	s	PROPN
american_scientific_journal-4355	424	9	,	,	PUNCT
american_scientific_journal-4355	424	10	casteilla	casteilla	PROPN
american_scientific_journal-4355	424	11	l	l	PROPN
american_scientific_journal-4355	424	12	,	,	PUNCT
american_scientific_journal-4355	424	13	chen	chen	PROPN
american_scientific_journal-4355	424	14	cw	cw	PROPN
american_scientific_journal-4355	424	15	,	,	PUNCT
american_scientific_journal-4355	424	16	2008;3:301–313	2008;3:301–313	NUM
american_scientific_journal-4355	424	17	.	.	PUNCT
american_scientific_journal-4355	425	1	[	[	X
american_scientific_journal-4355	425	2	pubmed	pubmed	X
american_scientific_journal-4355	425	3	]	]	PUNCT
american_scientific_journal-4355	425	4	.	.	PUNCT
american_scientific_journal-4355	426	1	[	[	X
american_scientific_journal-4355	426	2	32	32	NUM
american_scientific_journal-4355	426	3	]	]	PUNCT
american_scientific_journal-4355	426	4	john	john	PROPN
american_scientific_journal-4355	426	5	willey	willey	PROPN
american_scientific_journal-4355	426	6	,	,	PUNCT
american_scientific_journal-4355	426	7	2007	2007	NUM
american_scientific_journal-4355	427	1	[	[	X
american_scientific_journal-4355	427	2	33	33	NUM
american_scientific_journal-4355	427	3	]	]	X
american_scientific_journal-4355	427	4	plotkin	plotkin	PROPN
american_scientific_journal-4355	427	5	md	md	PROPN
american_scientific_journal-4355	427	6	,	,	PUNCT
american_scientific_journal-4355	427	7	goligorsky	goligorsky	PROPN
american_scientific_journal-4355	427	8	msam	msam	PROPN
american_scientific_journal-4355	427	9	j	j	PROPN
american_scientific_journal-4355	427	10	physiol	physiol	PROPN
american_scientific_journal-4355	427	11	renal	renal	PROPN
american_scientific_journal-4355	427	12	physiol	physiol	PROPN
american_scientific_journal-4355	427	13	.	.	PUNCT
american_scientific_journal-4355	428	1	2006;291	2006;291	NUM
american_scientific_journal-4355	428	2	:	:	PUNCT
american_scientific_journal-4355	428	3	f902	f902	PROPN
american_scientific_journal-4355	428	4	–	–	PUNCT
american_scientific_journal-4355	428	5	f912	f912	PROPN
american_scientific_journal-4355	428	6	.	.	PUNCT
american_scientific_journal-4355	429	1	[	[	X
american_scientific_journal-4355	429	2	pubmed	pubmed	X
american_scientific_journal-4355	429	3	]	]	X
american_scientific_journal-4355	430	1	[	[	X
american_scientific_journal-4355	430	2	34	34	NUM
american_scientific_journal-4355	430	3	]	]	PUNCT
american_scientific_journal-4355	430	4	.	.	PUNCT
american_scientific_journal-4355	431	1	phillips	phillips	PROPN
american_scientific_journal-4355	431	2	a.o	a.o	PROPN
american_scientific_journal-4355	431	3	.	.	PROPN
american_scientific_journal-4355	431	4	,	,	PUNCT
american_scientific_journal-4355	431	5	steadman	steadman	PROPN
american_scientific_journal-4355	431	6	r.	r.	PROPN
american_scientific_journal-4355	431	7	,	,	PUNCT
american_scientific_journal-4355	431	8	and	and	CCONJ
american_scientific_journal-4355	431	9	topley	topley	NOUN
american_scientific_journal-4355	431	10	n.	n.	NOUN
american_scientific_journal-4355	431	11	,	,	PUNCT
american_scientific_journal-4355	431	12	et	et	NOUN
american_scientific_journal-4355	431	13	al.(1995	al.(1995	PROPN
american_scientific_journal-4355	431	14	)	)	PUNCT
american_scientific_journal-4355	431	15	.	.	PUNCT
american_scientific_journal-4355	432	1	elevated	elevate	VERB
american_scientific_journal-4355	432	2	d	d	X
american_scientific_journal-4355	432	3	-	-	PUNCT
american_scientific_journal-4355	432	4	glucose	glucose	NOUN
american_scientific_journal-4355	432	5	concentrations	concentration	NOUN
american_scientific_journal-4355	432	6	modulategf	modulategf	NOUN
american_scientific_journal-4355	432	7	-	-	PUNCT
american_scientific_journal-4355	432	8	β1	β1	NOUN
american_scientific_journal-4355	432	9	synthesis	synthesis	NOUN
american_scientific_journal-4355	432	10	by	by	ADP
american_scientific_journal-4355	432	11	human	human	ADJ
american_scientific_journal-4355	432	12	cultured	cultured	ADJ
american_scientific_journal-4355	432	13	renal	renal	ADJ
american_scientific_journal-4355	432	14	proximal	proximal	ADJ
american_scientific_journal-4355	432	15	tubular	tubular	ADJ
american_scientific_journal-4355	432	16	cells	cell	NOUN
american_scientific_journal-4355	432	17	:	:	PUNCT
american_scientific_journal-4355	432	18	the	the	DET
american_scientific_journal-4355	432	19	permissive	permissive	ADJ
american_scientific_journal-4355	432	20	role	role	NOUN
american_scientific_journal-4355	432	21	of	of	ADP
american_scientific_journal-4355	432	22	platelett	platelett	ADJ
american_scientific_journal-4355	432	23	derived	derive	VERB
american_scientific_journal-4355	432	24	growth	growth	NOUN
american_scientific_journal-4355	432	25	factor	factor	NOUN
american_scientific_journal-4355	432	26	.	.	PUNCT
american_scientific_journal-4355	433	1	am	be	AUX
american_scientific_journal-4355	433	2	j	j	PROPN
american_scientific_journal-4355	433	3	pathol	pathol	NOUN
american_scientific_journal-4355	433	4	.147	.147	NUM
american_scientific_journal-4355	433	5	:	:	PUNCT
american_scientific_journal-4355	434	1	362−374	362−374	X
american_scientific_journal-4355	434	2	.	.	PUNCT
american_scientific_journal-4355	435	1	[	[	X
american_scientific_journal-4355	435	2	35	35	NUM
american_scientific_journal-4355	435	3	]	]	X
american_scientific_journal-4355	435	4	phillips	phillips	PROPN
american_scientific_journal-4355	435	5	a.o	a.o	PROPN
american_scientific_journal-4355	435	6	.	.	PROPN
american_scientific_journal-4355	435	7	,	,	PUNCT
american_scientific_journal-4355	435	8	topley	topley	NOUN
american_scientific_journal-4355	435	9	n.	n.	NOUN
american_scientific_journal-4355	435	10	,	,	PUNCT
american_scientific_journal-4355	435	11	and	and	CCONJ
american_scientific_journal-4355	435	12	morrisey	morrisey	PROPN
american_scientific_journal-4355	435	13	k	k	PROPN
american_scientific_journal-4355	435	14	et	et	PROPN
american_scientific_journal-4355	435	15	al	al	PROPN
american_scientific_journal-4355	435	16	.	.	PROPN
american_scientific_journal-4355	435	17	(	(	PUNCT
american_scientific_journal-4355	435	18	1997	1997	NUM
american_scientific_journal-4355	435	19	)	)	PUNCT
american_scientific_journal-4355	435	20	.	.	PUNCT
american_scientific_journal-4355	436	1	basic	basic	ADJ
american_scientific_journal-4355	436	2	fibroblast	fibroblast	ADJ
american_scientific_journal-4355	436	3	growth	growth	NOUN
american_scientific_journal-4355	436	4	factor	factor	NOUN
american_scientific_journal-4355	436	5	stimulates	stimulate	VERB
american_scientific_journal-4355	436	6	the	the	DET
american_scientific_journal-4355	436	7	release	release	NOUN
american_scientific_journal-4355	436	8	of	of	ADP
american_scientific_journal-4355	436	9	pre	pre	ADJ
american_scientific_journal-4355	436	10	-	-	ADJ
american_scientific_journal-4355	436	11	formed	form	VERB
american_scientific_journal-4355	436	12	tgf	tgf	PROPN
american_scientific_journal-4355	436	13	-	-	PUNCT
american_scientific_journal-4355	436	14	β1	β1	PROPN
american_scientific_journal-4355	436	15	from	from	ADP
american_scientific_journal-4355	436	16	human	human	ADJ
american_scientific_journal-4355	436	17	proximal	proximal	ADJ
american_scientific_journal-4355	436	18	tubular	tubular	ADJ
american_scientific_journal-4355	436	19	cells	cell	NOUN
american_scientific_journal-4355	436	20	in	in	ADP
american_scientific_journal-4355	436	21	the	the	DET
american_scientific_journal-4355	436	22	absence	absence	NOUN
american_scientific_journal-4355	436	23	of	of	ADP
american_scientific_journal-4355	436	24	de	de	NOUN
american_scientific_journal-4355	436	25	-	-	NOUN
american_scientific_journal-4355	436	26	novo	novo	NOUN
american_scientific_journal-4355	436	27	g	g	NOUN
american_scientific_journal-4355	436	28	transcription	transcription	NOUN
american_scientific_journal-4355	436	29	or	or	CCONJ
american_scientific_journal-4355	436	30	mrna	mrna	PROPN
american_scientific_journal-4355	436	31	translation	translation	NOUN
american_scientific_journal-4355	436	32	.	.	PUNCT
american_scientific_journal-4355	437	1	lab	lab	PROPN
american_scientific_journal-4355	437	2	invest	invest	VERB
american_scientific_journal-4355	437	3	.76	.76	NUM
american_scientific_journal-4355	437	4	:	:	PUNCT
american_scientific_journal-4355	438	1	591−600	591−600	X
american_scientific_journal-4355	438	2	.	.	PUNCT
american_scientific_journal-4355	439	1	[	[	X
american_scientific_journal-4355	439	2	36	36	NUM
american_scientific_journal-4355	439	3	]	]	X
american_scientific_journal-4355	439	4	ehiers	ehier	NOUN
american_scientific_journal-4355	439	5	m.	m.	PROPN
american_scientific_journal-4355	439	6	r.	r.	PROPN
american_scientific_journal-4355	439	7	w.	w.	PROPN
american_scientific_journal-4355	439	8	,	,	PUNCT
american_scientific_journal-4355	439	9	and	and	CCONJ
american_scientific_journal-4355	439	10	riordan	riordan	PROPN
american_scientific_journal-4355	439	11	j.	j.	PROPN
american_scientific_journal-4355	439	12	f.	f.	PROPN
american_scientific_journal-4355	439	13	(	(	PUNCT
american_scientific_journal-4355	439	14	1991	1991	NUM
american_scientific_journal-4355	439	15	)	)	PUNCT
american_scientific_journal-4355	439	16	.	.	PUNCT
american_scientific_journal-4355	440	1	membrane	membrane	NOUN
american_scientific_journal-4355	440	2	proteins	protein	NOUN
american_scientific_journal-4355	440	3	with	with	ADP
american_scientific_journal-4355	440	4	soluble	soluble	ADJ
american_scientific_journal-4355	440	5	counterparts	counterpart	NOUN
american_scientific_journal-4355	440	6	:	:	PUNCT
american_scientific_journal-4355	440	7	role	role	NOUN
american_scientific_journal-4355	440	8	of	of	ADP
american_scientific_journal-4355	440	9	proteolysis	proteolysis	NOUN
american_scientific_journal-4355	440	10	in	in	ADP
american_scientific_journal-4355	440	11	the	the	DET
american_scientific_journal-4355	440	12	release	release	NOUN
american_scientific_journal-4355	440	13	of	of	ADP
american_scientific_journal-4355	440	14	transmembrane	transmembrane	ADJ
american_scientific_journal-4355	440	15	proteins	protein	NOUN
american_scientific_journal-4355	440	16	.	.	PUNCT
american_scientific_journal-4355	441	1	biochemistry	biochemistry	NOUN
american_scientific_journal-4355	441	2	.	.	PUNCT
american_scientific_journal-4355	442	1	30:10065	30:10065	NUM
american_scientific_journal-4355	442	2	-	-	SYM
american_scientific_journal-4355	442	3	10074	10074	NUM
american_scientific_journal-4355	442	4	.	.	PUNCT
american_scientific_journal-4355	443	1	[	[	X
american_scientific_journal-4355	443	2	37	37	NUM
american_scientific_journal-4355	443	3	]	]	PUNCT
american_scientific_journal-4355	443	4	isaka	isaka	ADV
american_scientific_journal-4355	443	5	y.	y.	PROPN
american_scientific_journal-4355	443	6	,	,	PUNCT
american_scientific_journal-4355	443	7	tsujie	tsujie	PROPN
american_scientific_journal-4355	443	8	m.	m.	NOUN
american_scientific_journal-4355	443	9	,	,	PUNCT
american_scientific_journal-4355	443	10	ando	ando	PROPN
american_scientific_journal-4355	443	11	y	y	PROPN
american_scientific_journal-4355	443	12	,	,	PUNCT
american_scientific_journal-4355	443	13	et	et	PROPN
american_scientific_journal-4355	443	14	al	al	PROPN
american_scientific_journal-4355	443	15	(	(	PUNCT
american_scientific_journal-4355	443	16	2000).transforming	2000).transforme	VERB
american_scientific_journal-4355	443	17	growth	growth	NOUN
american_scientific_journal-4355	443	18	factor	factor	NOUN
american_scientific_journal-4355	443	19	-	-	PUNCT
american_scientific_journal-4355	443	20	beta1antisenseoligodeoxy	beta1antisenseoligodeoxy	ADJ
american_scientific_journal-4355	443	21	nucleotides	nucleotide	NOUN
american_scientific_journal-4355	443	22	block	block	VERB
american_scientific_journal-4355	443	23	interstitial	interstitial	ADJ
american_scientific_journal-4355	443	24	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	443	25	in	in	ADP
american_scientific_journal-4355	443	26	unilateral	unilateral	ADJ
american_scientific_journal-4355	443	27	ureteral	ureteral	ADJ
american_scientific_journal-4355	443	28	obstruction	obstruction	NOUN
american_scientific_journal-4355	443	29	.	.	PUNCT
american_scientific_journal-4355	444	1	kidney	kidney	NOUN
american_scientific_journal-4355	444	2	int	int	PROPN
american_scientific_journal-4355	444	3	,	,	PUNCT
american_scientific_journal-4355	444	4	58:1885	58:1885	NOUN
american_scientific_journal-4355	444	5	-	-	SYM
american_scientific_journal-4355	444	6	1892	1892	NUM
american_scientific_journal-4355	444	7	.	.	PUNCT
american_scientific_journal-4355	445	1	[	[	X
american_scientific_journal-4355	445	2	38	38	NUM
american_scientific_journal-4355	445	3	]	]	X
american_scientific_journal-4355	445	4	han	han	PROPN
american_scientific_journal-4355	445	5	d.c	d.c	PROPN
american_scientific_journal-4355	445	6	.	.	PROPN
american_scientific_journal-4355	445	7	,	,	PUNCT
american_scientific_journal-4355	445	8	hoffman	hoffman	PROPN
american_scientific_journal-4355	445	9	b.b	b.b	PROPN
american_scientific_journal-4355	445	10	.	.	PROPN
american_scientific_journal-4355	445	11	,	,	PUNCT
american_scientific_journal-4355	445	12	hong	hong	PROPN
american_scientific_journal-4355	445	13	s.w	s.w	PROPN
american_scientific_journal-4355	445	14	.	.	PROPN
american_scientific_journal-4355	445	15	,	,	PUNCT
american_scientific_journal-4355	445	16	guo	guo	PROPN
american_scientific_journal-4355	445	17	j,	j,	PROPN
american_scientific_journal-4355	445	18	.	.	PUNCT
american_scientific_journal-4355	445	19	,et	,et	PUNCT
american_scientific_journal-4355	445	20	al	al	PROPN
american_scientific_journal-4355	445	21	.	.	PROPN
american_scientific_journal-4355	445	22	(	(	PUNCT
american_scientific_journal-4355	445	23	2000	2000	NUM
american_scientific_journal-4355	445	24	)	)	PUNCT
american_scientific_journal-4355	445	25	.	.	PUNCT
american_scientific_journal-4355	446	1	therapy	therapy	NOUN
american_scientific_journal-4355	446	2	with	with	ADP
american_scientific_journal-4355	446	3	antisense	antisense	NOUN
american_scientific_journal-4355	446	4	tgf	tgf	PROPN
american_scientific_journal-4355	446	5	-	-	PUNCT
american_scientific_journal-4355	446	6	beta1oligodeoxy	beta1oligodeoxy	NOUN
american_scientific_journal-4355	446	7	nucleotides	nucleotide	NOUN
american_scientific_journal-4355	446	8	reduces	reduce	VERB
american_scientific_journal-4355	446	9	kidney	kidney	NOUN
american_scientific_journal-4355	446	10	weight	weight	NOUN
american_scientific_journal-4355	446	11	and	and	CCONJ
american_scientific_journal-4355	446	12	matrix	matrix	NOUN
american_scientific_journal-4355	446	13	rnas	rna	NOUN
american_scientific_journal-4355	446	14	in	in	ADP
american_scientific_journal-4355	446	15	diabetic	diabetic	ADJ
american_scientific_journal-4355	446	16	mice	mouse	NOUN
american_scientific_journal-4355	446	17	.	.	PUNCT
american_scientific_journal-4355	447	1	am	be	AUX
american_scientific_journal-4355	447	2	j	j	PROPN
american_scientific_journal-4355	447	3	physiol	physiol	PROPN
american_scientific_journal-4355	447	4	renal	renal	PROPN
american_scientific_journal-4355	447	5	physiol	physiol	PROPN
american_scientific_journal-4355	447	6	,	,	PUNCT
american_scientific_journal-4355	447	7	278(4):f628	278(4):f628	NUM
american_scientific_journal-4355	447	8	-	-	PUNCT
american_scientific_journal-4355	447	9	634	634	NUM
american_scientific_journal-4355	447	10	.	.	PUNCT
american_scientific_journal-4355	448	1	[	[	X
american_scientific_journal-4355	448	2	39	39	NUM
american_scientific_journal-4355	448	3	]	]	X
american_scientific_journal-4355	448	4	ji	ji	PROPN
american_scientific_journal-4355	448	5	c.	c.	PROPN
american_scientific_journal-4355	448	6	,	,	PUNCT
american_scientific_journal-4355	448	7	chen	chen	PROPN
american_scientific_journal-4355	448	8	y.	y.	PROPN
american_scientific_journal-4355	448	9	,	,	PUNCT
american_scientific_journal-4355	448	10	mccarthy	mccarthy	PROPN
american_scientific_journal-4355	448	11	t.	t.	PROPN
american_scientific_journal-4355	448	12	l.	l.	PROPN
american_scientific_journal-4355	448	13	,	,	PUNCT
american_scientific_journal-4355	448	14	centrella	centrella	PROPN
american_scientific_journal-4355	448	15	m.	m.	NOUN
american_scientific_journal-4355	448	16	(	(	PUNCT
american_scientific_journal-4355	448	17	1999	1999	NUM
american_scientific_journal-4355	448	18	)	)	PUNCT
american_scientific_journal-4355	448	19	.	.	PUNCT
american_scientific_journal-4355	449	1	cloning	clone	VERB
american_scientific_journal-4355	449	2	the	the	DET
american_scientific_journal-4355	449	3	promoter	promoter	NOUN
american_scientific_journal-4355	449	4	for	for	ADP
american_scientific_journal-4355	449	5	transforming	transform	VERB
american_scientific_journal-4355	449	6	growthfactor	growthfactor	NOUN
american_scientific_journal-4355	449	7	-	-	PUNCT
american_scientific_journal-4355	449	8	b	b	NOUN
american_scientific_journal-4355	449	9	type	type	NOUN
american_scientific_journal-4355	449	10	iii	iii	NUM
american_scientific_journal-4355	449	11	receptor	receptor	NOUN
american_scientific_journal-4355	449	12	.	.	PUNCT
american_scientific_journal-4355	450	1	j.	j.	PROPN
american_scientific_journal-4355	450	2	biol	biol	PROPN
american_scientific_journal-4355	450	3	.	.	PUNCT
american_scientific_journal-4355	451	1	chem	chem	NOUN
american_scientific_journal-4355	451	2	.	.	PUNCT
american_scientific_journal-4355	452	1	274:30487	274:30487	NUM
american_scientific_journal-4355	452	2	-	-	SYM
american_scientific_journal-4355	452	3	30494	30494	NUM
american_scientific_journal-4355	452	4	.	.	PUNCT
american_scientific_journal-4355	453	1	[	[	X
american_scientific_journal-4355	453	2	40	40	NUM
american_scientific_journal-4355	453	3	]	]	PUNCT
american_scientific_journal-4355	453	4	centrella	centrella	NOUN
american_scientific_journal-4355	453	5	,	,	PUNCT
american_scientific_journal-4355	453	6	m.	m.	NOUN
american_scientific_journal-4355	453	7	,	,	PUNCT
american_scientific_journal-4355	453	8	casinghino	casinghino	PROPN
american_scientific_journal-4355	453	9	s.	s.	PROPN
american_scientific_journal-4355	453	10	,	,	PUNCT
american_scientific_journal-4355	453	11	kim	kim	PROPN
american_scientific_journal-4355	453	12	j.	j.	PROPN
american_scientific_journal-4355	453	13	,	,	PUNCT
american_scientific_journal-4355	453	14	pham	pham	PROPN
american_scientific_journal-4355	453	15	t	t	PROPN
american_scientific_journal-4355	453	16	,	,	PUNCT
american_scientific_journal-4355	453	17	et	et	PROPN
american_scientific_journal-4355	453	18	al	al	PROPN
american_scientific_journal-4355	453	19	.	.	PUNCT
american_scientific_journal-4355	454	1	(	(	PUNCT
american_scientific_journal-4355	454	2	1995).independent	1995).independent	NUM
american_scientific_journal-4355	454	3	changes	change	NOUN
american_scientific_journal-4355	454	4	in	in	ADP
american_scientific_journal-4355	454	5	type	type	NOUN
american_scientific_journal-4355	454	6	i	i	PRON
american_scientific_journal-4355	454	7	and	and	CCONJ
american_scientific_journal-4355	454	8	type	type	NOUN
american_scientific_journal-4355	454	9	ii	ii	NOUN
american_scientific_journal-4355	454	10	receptors	receptor	NOUN
american_scientific_journal-4355	454	11	for	for	ADP
american_scientific_journal-4355	454	12	transforming	transform	VERB
american_scientific_journal-4355	454	13	growth	growth	NOUN
american_scientific_journal-4355	454	14	factor	factor	NOUN
american_scientific_journal-4355	454	15	beta	beta	NOUN
american_scientific_journal-4355	454	16	induced	induce	VERB
american_scientific_journal-4355	454	17	by	by	ADP
american_scientific_journal-4355	454	18	bone	bone	NOUN
american_scientific_journal-4355	454	19	morphogenetic	morphogenetic	ADJ
american_scientific_journal-4355	454	20	protein	protein	NOUN
american_scientific_journal-4355	454	21	2	2	NUM
american_scientific_journal-4355	454	22	parallel	parallel	NOUN
american_scientific_journal-4355	454	23	expression	expression	NOUN
american_scientific_journal-4355	454	24	of	of	ADP
american_scientific_journal-4355	454	25	the	the	DET
american_scientific_journal-4355	454	26	osteoblast	osteoblast	ADJ
american_scientific_journal-4355	454	27	phenotype	phenotype	NOUN
american_scientific_journal-4355	454	28	.	.	PUNCT
american_scientific_journal-4355	455	1	mol	mol	PROPN
american_scientific_journal-4355	455	2	.	.	PROPN
american_scientific_journal-4355	455	3	cell	cell	NOUN
american_scientific_journal-4355	455	4	.	.	PUNCT
american_scientific_journal-4355	456	1	biol	biol	PROPN
american_scientific_journal-4355	456	2	,	,	PUNCT
american_scientific_journal-4355	456	3	15:3273	15:3273	NUM
american_scientific_journal-4355	456	4	-	-	PUNCT
american_scientific_journal-4355	456	5	3281	3281	NUM
american_scientific_journal-4355	456	6	.	.	PUNCT
american_scientific_journal-4355	457	1	[	[	X
american_scientific_journal-4355	457	2	41	41	NUM
american_scientific_journal-4355	457	3	]	]	PUNCT
american_scientific_journal-4355	457	4	kohan	kohan	PROPN
american_scientific_journal-4355	457	5	d.e	d.e	PROPN
american_scientific_journal-4355	457	6	.	.	PROPN
american_scientific_journal-4355	458	1	(	(	PUNCT
american_scientific_journal-4355	458	2	1991	1991	NUM
american_scientific_journal-4355	458	3	)	)	PUNCT
american_scientific_journal-4355	458	4	.	.	PUNCT
american_scientific_journal-4355	459	1	endothelin	endothelin	PROPN
american_scientific_journal-4355	459	2	synthesis	synthesis	NOUN
american_scientific_journal-4355	459	3	by	by	ADP
american_scientific_journal-4355	459	4	renal	renal	ADJ
american_scientific_journal-4355	459	5	tubule	tubule	NOUN
american_scientific_journal-4355	459	6	cells.am	cells.am	PROPN
american_scientific_journal-4355	459	7	j	j	PROPN
american_scientific_journal-4355	459	8	physiol	physiol	PROPN
american_scientific_journal-4355	459	9	261(2	261(2	NUM
american_scientific_journal-4355	459	10	pt	pt	PROPN
american_scientific_journal-4355	459	11	2	2	NUM
american_scientific_journal-4355	459	12	):	):	PUNCT
american_scientific_journal-4355	459	13	f221	f221	NOUN
american_scientific_journal-4355	459	14	-	-	SYM
american_scientific_journal-4355	459	15	6	6	NUM
american_scientific_journal-4355	459	16	.	.	PUNCT
american_scientific_journal-4355	460	1	[	[	X
american_scientific_journal-4355	460	2	42	42	NUM
american_scientific_journal-4355	460	3	]	]	PUNCT
american_scientific_journal-4355	460	4	rider	rider	NOUN
american_scientific_journal-4355	460	5	c.c	c.c	PROPN
american_scientific_journal-4355	460	6	.	.	PROPN
american_scientific_journal-4355	460	7	(	(	PUNCT
american_scientific_journal-4355	460	8	2006	2006	NUM
american_scientific_journal-4355	460	9	)	)	PUNCT
american_scientific_journal-4355	460	10	.	.	PUNCT
american_scientific_journal-4355	461	1	heparin	heparin	NOUN
american_scientific_journal-4355	461	2	/	/	SYM
american_scientific_journal-4355	461	3	heparan	heparan	ADJ
american_scientific_journal-4355	461	4	sulphate	sulphate	NOUN
american_scientific_journal-4355	461	5	binding	bind	VERB
american_scientific_journal-4355	461	6	in	in	ADP
american_scientific_journal-4355	461	7	the	the	DET
american_scientific_journal-4355	461	8	tgf	tgf	NOUN
american_scientific_journal-4355	461	9	-	-	PUNCT
american_scientific_journal-4355	461	10	beta	beta	NOUN
american_scientific_journal-4355	461	11	cytokine	cytokine	NOUN
american_scientific_journal-4355	461	12	superfamily	superfamily	ADV
american_scientific_journal-4355	461	13	.	.	PUNCT
american_scientific_journal-4355	462	1	biochem	biochem	PROPN
american_scientific_journal-4355	462	2	soc	soc	PROPN
american_scientific_journal-4355	462	3	trans	trans	PROPN
american_scientific_journal-4355	462	4	.	.	PUNCT
american_scientific_journal-4355	463	1	34(pt	34(pt	NUM
american_scientific_journal-4355	463	2	3):458	3):458	NUM
american_scientific_journal-4355	463	3	-	-	SYM
american_scientific_journal-4355	463	4	60	60	NUM
american_scientific_journal-4355	463	5	.	.	PUNCT
american_scientific_journal-4355	464	1	[	[	X
american_scientific_journal-4355	464	2	43	43	NUM
american_scientific_journal-4355	464	3	]	]	X
american_scientific_journal-4355	464	4	chun	chun	PROPN
american_scientific_journal-4355	464	5	-	-	PUNCT
american_scientific_journal-4355	464	6	lin	lin	PROPN
american_scientific_journal-4355	464	7	chen	chen	PROPN
american_scientific_journal-4355	464	8	.	.	PROPN
american_scientific_journal-4355	464	9	,	,	PUNCT
american_scientific_journal-4355	464	10	shuan	shuan	PROPN
american_scientific_journal-4355	464	11	shian	shian	PROPN
american_scientific_journal-4355	464	12	huang	huang	PROPN
american_scientific_journal-4355	464	13	.	.	PROPN
american_scientific_journal-4355	464	14	,	,	PUNCT
american_scientific_journal-4355	464	15	and	and	CCONJ
american_scientific_journal-4355	464	16	jung	jung	PROPN
american_scientific_journal-4355	464	17	san	san	PROPN
american_scientific_journal-4355	464	18	huang	huang	PROPN
american_scientific_journal-4355	464	19	.	.	PUNCT
american_scientific_journal-4355	465	1	(	(	PUNCT
american_scientific_journal-4355	465	2	2006	2006	NUM
american_scientific_journal-4355	465	3	)	)	PUNCT
american_scientific_journal-4355	465	4	.	.	PUNCT
american_scientific_journal-4355	466	1	cellular	cellular	ADJ
american_scientific_journal-4355	466	2	heparan	heparan	ADJ
american_scientific_journal-4355	466	3	sulfatenegatively	sulfatenegatively	ADJ
american_scientific_journal-4355	466	4	modulates	modulate	NOUN
american_scientific_journal-4355	466	5	transforming	transform	VERB
american_scientific_journal-4355	466	6	growth	growth	NOUN
american_scientific_journal-4355	466	7	factor	factor	NOUN
american_scientific_journal-4355	466	8	-	-	PUNCT
american_scientific_journal-4355	466	9	β1(tgf	β1(tgf	NUM
american_scientific_journal-4355	466	10	-	-	PUNCT
american_scientific_journal-4355	466	11	β	β	NOUN
american_scientific_journal-4355	466	12	)	)	PUNCT
american_scientific_journal-4355	466	13	responsiveness	responsiveness	NOUN
american_scientific_journal-4355	466	14	in	in	ADP
american_scientific_journal-4355	466	15	epithelial	epithelial	ADJ
american_scientific_journal-4355	466	16	cells.the	cells.the	DET
american_scientific_journal-4355	466	17	journal	journal	NOUN
american_scientific_journal-4355	466	18	of	of	ADP
american_scientific_journal-4355	466	19	biological	biological	ADJ
american_scientific_journal-4355	466	20	chemistry	chemistry	NOUN
american_scientific_journal-4355	466	21	.	.	PUNCT
american_scientific_journal-4355	467	1	vol	vol	NOUN
american_scientific_journal-4355	467	2	.	.	PROPN
american_scientific_journal-4355	468	1	281	281	NUM
american_scientific_journal-4355	468	2	,	,	PUNCT
american_scientific_journal-4355	468	3	no	no	INTJ
american_scientific_journal-4355	468	4	.	.	NOUN
american_scientific_journal-4355	468	5	17	17	NUM
american_scientific_journal-4355	468	6	,	,	PUNCT
american_scientific_journal-4355	468	7	pp	pp	ADJ
american_scientific_journal-4355	468	8	.	.	PUNCT
american_scientific_journal-4355	469	1	11506	11506	NUM
american_scientific_journal-4355	469	2	-	-	SYM
american_scientific_journal-4355	469	3	11514	11514	NUM
american_scientific_journal-4355	469	4	.	.	PUNCT
american_scientific_journal-4355	470	1	[	[	X
american_scientific_journal-4355	470	2	44	44	NUM
american_scientific_journal-4355	470	3	]	]	X
american_scientific_journal-4355	470	4	hulpiau	hulpiau	PROPN
american_scientific_journal-4355	470	5	p.	p.	PROPN
american_scientific_journal-4355	470	6	,	,	PUNCT
american_scientific_journal-4355	470	7	and	and	CCONJ
american_scientific_journal-4355	470	8	van	van	PROPN
american_scientific_journal-4355	470	9	roy	roy	PROPN
american_scientific_journal-4355	470	10	f.	f.	PROPN
american_scientific_journal-4355	470	11	(	(	PUNCT
american_scientific_journal-4355	470	12	2009	2009	NUM
american_scientific_journal-4355	470	13	)	)	PUNCT
american_scientific_journal-4355	470	14	.	.	PUNCT
american_scientific_journal-4355	471	1	molecular	molecular	ADJ
american_scientific_journal-4355	471	2	evolution	evolution	NOUN
american_scientific_journal-4355	471	3	of	of	ADP
american_scientific_journal-4355	471	4	the	the	DET
american_scientific_journal-4355	471	5	cadherin	cadherin	NOUN
american_scientific_journal-4355	471	6	superfamily	superfamily	NOUN
american_scientific_journal-4355	471	7	.	.	PUNCT
american_scientific_journal-4355	472	1	int	int	NOUN
american_scientific_journal-4355	472	2	.	.	PUNCT
american_scientific_journal-4355	473	1	j.	j.	PROPN
american_scientific_journal-4355	473	2	biochem.cell	biochem.cell	PROPN
american_scientific_journal-4355	473	3	biol	biol	PROPN
american_scientific_journal-4355	473	4	,	,	PUNCT
american_scientific_journal-4355	473	5	41(2):349	41(2):349	NOUN
american_scientific_journal-4355	473	6	-	-	SYM
american_scientific_journal-4355	473	7	69	69	NUM
american_scientific_journal-4355	473	8	.	.	PUNCT
american_scientific_journal-4355	474	1	[	[	X
american_scientific_journal-4355	474	2	45	45	NUM
american_scientific_journal-4355	474	3	]	]	X
american_scientific_journal-4355	474	4	angst	angst	PROPN
american_scientific_journal-4355	474	5	b.	b.	PROPN
american_scientific_journal-4355	474	6	,	,	PUNCT
american_scientific_journal-4355	474	7	marcozzi	marcozzi	PROPN
american_scientific_journal-4355	474	8	c.	c.	PROPN
american_scientific_journal-4355	474	9	,	,	PUNCT
american_scientific_journal-4355	474	10	and	and	CCONJ
american_scientific_journal-4355	474	11	magee	magee	PROPN
american_scientific_journal-4355	474	12	a.	a.	PROPN
american_scientific_journal-4355	474	13	(	(	PUNCT
american_scientific_journal-4355	474	14	february	february	PROPN
american_scientific_journal-4355	474	15	2001	2001	NUM
american_scientific_journal-4355	474	16	)	)	PUNCT
american_scientific_journal-4355	474	17	.	.	PUNCT
american_scientific_journal-4355	475	1	the	the	DET
american_scientific_journal-4355	475	2	cadherin	cadherin	NOUN
american_scientific_journal-4355	475	3	superfamily	superfamily	NOUN
american_scientific_journal-4355	475	4	:	:	PUNCT
american_scientific_journal-4355	475	5	diversity	diversity	NOUN
american_scientific_journal-4355	475	6	in	in	ADP
american_scientific_journal-4355	475	7	form	form	NOUN
american_scientific_journal-4355	475	8	and	and	CCONJ
american_scientific_journal-4355	475	9	function	function	NOUN
american_scientific_journal-4355	475	10	.	.	PUNCT
american_scientific_journal-4355	476	1	j	j	PROPN
american_scientific_journal-4355	476	2	cell	cell	PROPN
american_scientific_journal-4355	476	3	sci	sci	PROPN
american_scientific_journal-4355	476	4	,	,	PUNCT
american_scientific_journal-4355	476	5	114(pt	114(pt	NUM
american_scientific_journal-4355	476	6	4):629	4):629	NOUN
american_scientific_journal-4355	476	7	-	-	SYM
american_scientific_journal-4355	476	8	41	41	NUM
american_scientific_journal-4355	477	1	[	[	X
american_scientific_journal-4355	477	2	46	46	NUM
american_scientific_journal-4355	477	3	]	]	X
american_scientific_journal-4355	477	4	ueyama	ueyama	PROPN
american_scientific_journal-4355	477	5	h.	h.	PROPN
american_scientific_journal-4355	477	6	,	,	PUNCT
american_scientific_journal-4355	477	7	bruns	bruns	PROPN
american_scientific_journal-4355	477	8	g.	g.	PROPN
american_scientific_journal-4355	477	9	,and	,and	PUNCT
american_scientific_journal-4355	477	10	kanda	kanda	PROPN
american_scientific_journal-4355	477	11	n.	n.	PROPN
american_scientific_journal-4355	477	12	(	(	PUNCT
american_scientific_journal-4355	477	13	1990	1990	NUM
american_scientific_journal-4355	477	14	)	)	PUNCT
american_scientific_journal-4355	477	15	.	.	PUNCT
american_scientific_journal-4355	478	1	assignment	assignment	NOUN
american_scientific_journal-4355	478	2	of	of	ADP
american_scientific_journal-4355	478	3	the	the	DET
american_scientific_journal-4355	478	4	vascular	vascular	ADJ
american_scientific_journal-4355	478	5	smooth	smooth	ADJ
american_scientific_journal-4355	478	6	muscle	muscle	NOUN
american_scientific_journal-4355	478	7	actin	actin	NOUN
american_scientific_journal-4355	478	8	gene	gene	NOUN
american_scientific_journal-4355	478	9	actsa	actsa	NOUN
american_scientific_journal-4355	478	10	to	to	ADP
american_scientific_journal-4355	478	11	human	human	ADJ
american_scientific_journal-4355	478	12	chromosome	chromosome	NOUN
american_scientific_journal-4355	478	13	10	10	NUM
american_scientific_journal-4355	478	14	.	.	PUNCT
american_scientific_journal-4355	479	1	jinrui	jinrui	PROPN
american_scientific_journal-4355	479	2	idengaku	idengaku	PROPN
american_scientific_journal-4355	479	3	zasshi	zasshi	PROPN
american_scientific_journal-4355	479	4	35	35	NUM
american_scientific_journal-4355	479	5	(	(	PUNCT
american_scientific_journal-4355	479	6	2	2	NUM
american_scientific_journal-4355	479	7	):	):	PUNCT
american_scientific_journal-4355	479	8	145–50	145–50	ADJ
american_scientific_journal-4355	479	9	.	.	PUNCT
american_scientific_journal-4355	480	1	[	[	X
american_scientific_journal-4355	480	2	47	47	NUM
american_scientific_journal-4355	480	3	]	]	PUNCT
american_scientific_journal-4355	480	4	chebotareva	chebotareva	PROPN
american_scientific_journal-4355	480	5	n.v	n.v	PROPN
american_scientific_journal-4355	480	6	.	.	PROPN
american_scientific_journal-4355	480	7	,	,	PUNCT
american_scientific_journal-4355	480	8	proppe	proppe	PROPN
american_scientific_journal-4355	480	9	d.	d.	PROPN
american_scientific_journal-4355	480	10	,	,	PUNCT
american_scientific_journal-4355	480	11	rudolf	rudolf	PROPN
american_scientific_journal-4355	480	12	p.	p.	NOUN
american_scientific_journal-4355	480	13	,	,	PUNCT
american_scientific_journal-4355	480	14	and	and	CCONJ
american_scientific_journal-4355	480	15	kozlovskaia	kozlovskaia	VERB
american_scientific_journal-4355	480	16	lv	lv	PROPN
american_scientific_journal-4355	480	17	.	.	PUNCT
american_scientific_journal-4355	480	18	(	(	PUNCT
american_scientific_journal-4355	480	19	2002	2002	NUM
american_scientific_journal-4355	480	20	)	)	PUNCT
american_scientific_journal-4355	480	21	.	.	PUNCT
american_scientific_journal-4355	481	1	clinical	clinical	ADJ
american_scientific_journal-4355	481	2	significance	significance	NOUN
american_scientific_journal-4355	481	3	of	of	ADP
american_scientific_journal-4355	481	4	expression	expression	NOUN
american_scientific_journal-4355	481	5	of	of	ADP
american_scientific_journal-4355	481	6	the	the	DET
american_scientific_journal-4355	481	7	smooth	smooth	ADJ
american_scientific_journal-4355	481	8	muscle	muscle	NOUN
american_scientific_journal-4355	481	9	actin	actin	NOUN
american_scientific_journal-4355	481	10	-	-	PUNCT
american_scientific_journal-4355	481	11	alpha	alpha	NOUN
american_scientific_journal-4355	481	12	and	and	CCONJ
american_scientific_journal-4355	481	13	cd34	cd34	PROPN
american_scientific_journal-4355	481	14	antigen	antigen	NOUN
american_scientific_journal-4355	481	15	in	in	ADP
american_scientific_journal-4355	481	16	mesangial	mesangial	ADJ
american_scientific_journal-4355	481	17	cells	cell	NOUN
american_scientific_journal-4355	481	18	in	in	ADP
american_scientific_journal-4355	481	19	glomerulonephritis	glomerulonephritis	NOUN
american_scientific_journal-4355	481	20	.	.	PUNCT
american_scientific_journal-4355	482	1	ter	ter	PROPN
american_scientific_journal-4355	482	2	arkh	arkh	PROPN
american_scientific_journal-4355	482	3	,	,	PUNCT
american_scientific_journal-4355	482	4	74(6):27	74(6):27	PROPN
american_scientific_journal-4355	482	5	-	-	SYM
american_scientific_journal-4355	482	6	31	31	NUM
american_scientific_journal-4355	482	7	.	.	PUNCT
american_scientific_journal-4355	483	1	[	[	X
american_scientific_journal-4355	483	2	48	48	NUM
american_scientific_journal-4355	483	3	]	]	SYM
american_scientific_journal-4355	483	4	de	de	X
american_scientific_journal-4355	483	5	autocrine	autocrine	NOUN
american_scientific_journal-4355	483	6	and	and	CCONJ
american_scientific_journal-4355	483	7	exogenous	exogenous	ADJ
american_scientific_journal-4355	483	8	transforming	transform	VERB
american_scientific_journal-4355	483	9	growth	growth	NOUN
american_scientific_journal-4355	483	10	factor	factor	NOUN
american_scientific_journal-4355	483	11	(	(	PUNCT
american_scientific_journal-4355	483	12	tgf	tgf	PROPN
american_scientific_journal-4355	483	13	)	)	PUNCT
american_scientific_journal-4355	483	14	ß1	ß1	PROPN
american_scientific_journal-4355	483	15	in	in	ADP
american_scientific_journal-4355	483	16	cells	cell	NOUN
american_scientific_journal-4355	483	17	with	with	ADP
american_scientific_journal-4355	483	18	nonfunctional	nonfunctional	ADJ
american_scientific_journal-4355	483	19	tgf	tgf	PROPN
american_scientific_journal-4355	483	20	-	-	PUNCT
american_scientific_journal-4355	483	21	ß	ß	NOUN
american_scientific_journal-4355	483	22	receptor	receptor	NOUN
american_scientific_journal-4355	483	23	type	type	NOUN
american_scientific_journal-4355	483	24	iii	iii	PROPN
american_scientific_journal-4355	483	25	.	.	PUNCT
american_scientific_journal-4355	484	1	(	(	PUNCT
american_scientific_journal-4355	484	2	cell	cell	NOUN
american_scientific_journal-4355	484	3	growth	growth	NOUN
american_scientific_journal-4355	484	4	&	&	CCONJ
american_scientific_journal-4355	484	5	differentiation	differentiation	NOUN
american_scientific_journal-4355	484	6	vol	vol	NOUN
american_scientific_journal-4355	484	7	.	.	PROPN
american_scientific_journal-4355	484	8	10	10	NUM
american_scientific_journal-4355	484	9	,	,	PUNCT
american_scientific_journal-4355	484	10	11	11	NUM
american_scientific_journal-4355	484	11	-	-	SYM
american_scientific_journal-4355	484	12	18	18	NUM
american_scientific_journal-4355	484	13	.	.	PUNCT
american_scientific_journal-4355	485	1	ng	ng	PROPN
american_scientific_journal-4355	485	2	x.	x.	PROPN
american_scientific_journal-4355	485	3	,	,	PUNCT
american_scientific_journal-4355	485	4	bellis	bellis	PROPN
american_scientific_journal-4355	485	5	s.	s.	PROPN
american_scientific_journal-4355	485	6	,	,	PUNCT
american_scientific_journal-4355	485	7	zhongfa	zhongfa	PROPN
american_scientific_journal-4355	485	8	yan	yan	PROPN
american_scientific_journal-4355	485	9	.	.	PROPN
american_scientific_journal-4355	485	10	,	,	PUNCT
american_scientific_journal-4355	485	11	and	and	CCONJ
american_scientific_journal-4355	485	12	eileen	eileen	PROPN
american_scientific_journal-4355	485	13	friedman	friedman	PROPN
american_scientific_journal-4355	485	14	.	.	PUNCT
american_scientific_journal-4355	486	1	(	(	PUNCT
american_scientific_journal-4355	486	2	1999	1999	NUM
american_scientific_journal-4355	486	3	)	)	PUNCT
american_scientific_journal-4355	486	4	.	.	PUNCT
american_scientific_journal-4355	487	1	differential	differential	ADJ
american_scientific_journal-4355	487	2	responsiveness	responsiveness	NOUN
american_scientific_journal-4355	487	3	to	to	ADP
american_scientific_journal-4355	487	4	[	[	X
american_scientific_journal-4355	487	5	49	49	NUM
american_scientific_journal-4355	487	6	]	]	SYM
american_scientific_journal-4355	487	7	brown	brown	PROPN
american_scientific_journal-4355	487	8	c.	c.	PROPN
american_scientific_journal-4355	487	9	b.	b.	PROPN
american_scientific_journal-4355	487	10	,	,	PUNCT
american_scientific_journal-4355	487	11	boyer	boyer	PROPN
american_scientific_journal-4355	487	12	a.	a.	PROPN
american_scientific_journal-4355	487	13	s.	s.	PROPN
american_scientific_journal-4355	487	14	,	,	PUNCT
american_scientific_journal-4355	487	15	runyan	runyan	PROPN
american_scientific_journal-4355	487	16	r.	r.	PROPN
american_scientific_journal-4355	487	17	b.	b.	PROPN
american_scientific_journal-4355	487	18	,	,	PUNCT
american_scientific_journal-4355	487	19	joey	joey	PROPN
american_scientific_journal-4355	487	20	v.	v.	PROPN
american_scientific_journal-4355	487	21	,	,	PUNCT
american_scientific_journal-4355	487	22	et	et	PROPN
american_scientific_journal-4355	487	23	al	al	PROPN
american_scientific_journal-4355	487	24	.	.	PUNCT
american_scientific_journal-4355	488	1	(	(	PUNCT
american_scientific_journal-4355	488	2	1999	1999	NUM
american_scientific_journal-4355	488	3	)	)	PUNCT
american_scientific_journal-4355	488	4	.	.	PUNCT
american_scientific_journal-4355	489	1	requirement	requirement	NOUN
american_scientific_journal-4355	489	2	of	of	ADP
american_scientific_journal-4355	489	3	type	type	PROPN
american_scientific_journal-4355	489	4	iii	iii	PROPN
american_scientific_journal-4355	489	5	tgf	tgf	PROPN
american_scientific_journal-4355	489	6	-	-	PUNCT
american_scientific_journal-4355	489	7	β	β	NOUN
american_scientific_journal-4355	489	8	receptor	receptor	NOUN
american_scientific_journal-4355	489	9	for	for	ADP
american_scientific_journal-4355	489	10	endocardial	endocardial	ADJ
american_scientific_journal-4355	489	11	cell	cell	NOUN
american_scientific_journal-4355	489	12	transformation	transformation	NOUN
american_scientific_journal-4355	489	13	in	in	ADP
american_scientific_journal-4355	489	14	the	the	DET
american_scientific_journal-4355	489	15	heart	heart	NOUN
american_scientific_journal-4355	489	16	.	.	PUNCT
american_scientific_journal-4355	490	1	american	american	PROPN
american_scientific_journal-4355	490	2	journal	journal	PROPN
american_scientific_journal-4355	490	3	experts	expert	NOUN
american_scientific_journal-4355	490	4	.	.	PUNCT
american_scientific_journal-4355	491	1	vol	vol	NOUN
american_scientific_journal-4355	491	2	.	.	PUNCT
american_scientific_journal-4355	492	1	283	283	NUM
american_scientific_journal-4355	492	2	.	.	PUNCT
american_scientific_journal-4355	493	1	no	no	INTJ
american_scientific_journal-4355	493	2	.	.	NOUN
american_scientific_journal-4355	494	1	5410	5410	NUM
american_scientific_journal-4355	494	2	,	,	PUNCT
american_scientific_journal-4355	494	3	2080	2080	NUM
american_scientific_journal-4355	494	4	2082	2082	NUM
american_scientific_journal-4355	494	5	.	.	PUNCT
american_scientific_journal-4355	495	1	[	[	X
american_scientific_journal-4355	495	2	50	50	NUM
american_scientific_journal-4355	495	3	]	]	PUNCT
american_scientific_journal-4355	495	4	yang	yang	PROPN
american_scientific_journal-4355	495	5	dong	dong	PROPN
american_scientific_journal-4355	495	6	;	;	PUNCT
american_scientific_journal-4355	495	7	du	du	PROPN
american_scientific_journal-4355	495	8	yong	yong	PROPN
american_scientific_journal-4355	495	9	-	-	PUNCT
american_scientific_journal-4355	495	10	ping	ping	PROPN
american_scientific_journal-4355	495	11	,	,	PUNCT
american_scientific_journal-4355	495	12	2008	2008	NUM
american_scientific_journal-4355	495	13	.	.	PUNCT
american_scientific_journal-4355	496	1	yang	yang	PROPN
american_scientific_journal-4355	496	2	j.	j.	PROPN
american_scientific_journal-4355	496	3	,	,	PUNCT
american_scientific_journal-4355	496	4	and	and	CCONJ
american_scientific_journal-4355	496	5	weinberg	weinberg	PROPN
american_scientific_journal-4355	496	6	r.a	r.a	PROPN
american_scientific_journal-4355	496	7	.	.	PROPN
american_scientific_journal-4355	496	8	(	(	PUNCT
american_scientific_journal-4355	496	9	2008	2008	NUM
american_scientific_journal-4355	496	10	)	)	PUNCT
american_scientific_journal-4355	496	11	.	.	PUNCT
american_scientific_journal-4355	497	1	epithelial	epithelial	ADJ
american_scientific_journal-4355	497	2	-	-	PUNCT
american_scientific_journal-4355	497	3	mesenchymal	mesenchymal	NOUN
american_scientific_journal-4355	497	4	transition	transition	NOUN
american_scientific_journal-4355	497	5	:	:	PUNCT
american_scientific_journal-4355	497	6	at	at	ADP
american_scientific_journal-4355	497	7	the	the	DET
american_scientific_journal-4355	497	8	crossroads	crossroad	NOUN
american_scientific_journal-4355	497	9	of	of	ADP
american_scientific_journal-4355	497	10	development	development	NOUN
american_scientific_journal-4355	497	11	and	and	CCONJ
american_scientific_journal-4355	497	12	tumor	tumor	NOUN
american_scientific_journal-4355	497	13	metastasis	metastasis	NOUN
american_scientific_journal-4355	497	14	.	.	PUNCT
american_scientific_journal-4355	498	1	dev	dev	PROPN
american_scientific_journal-4355	498	2	cell	cell	NOUN
american_scientific_journal-4355	498	3	14(6):818	14(6):818	PROPN
american_scientific_journal-4355	498	4	-	-	PUNCT
american_scientific_journal-4355	498	5	829	829	NUM
american_scientific_journal-4355	498	6	.	.	PUNCT
american_scientific_journal-4355	499	1	[	[	X
american_scientific_journal-4355	499	2	51	51	NUM
american_scientific_journal-4355	499	3	]	]	X
american_scientific_journal-4355	499	4	liu	liu	PROPN
american_scientific_journal-4355	499	5	m.	m.	PROPN
american_scientific_journal-4355	499	6	,	,	PUNCT
american_scientific_journal-4355	499	7	suga	suga	PROPN
american_scientific_journal-4355	499	8	m.	m.	PROPN
american_scientific_journal-4355	499	9	,	,	PUNCT
american_scientific_journal-4355	499	10	maclean	maclean	PROPN
american_scientific_journal-4355	499	11	a.a	a.a	PROPN
american_scientific_journal-4355	499	12	.	.	PROPN
american_scientific_journal-4355	499	13	,	,	PUNCT
american_scientific_journal-4355	499	14	st	st	PROPN
american_scientific_journal-4355	499	15	george	george	PROPN
american_scientific_journal-4355	499	16	j.a	j.a	PROPN
american_scientific_journal-4355	499	17	.	.	PROPN
american_scientific_journal-4355	499	18	,et	,et	PUNCT
american_scientific_journal-4355	499	19	al	al	PROPN
american_scientific_journal-4355	499	20	.	.	PROPN
american_scientific_journal-4355	499	21	(	(	PUNCT
american_scientific_journal-4355	499	22	2002	2002	NUM
american_scientific_journal-4355	499	23	)	)	PUNCT
american_scientific_journal-4355	499	24	.	.	PUNCT
american_scientific_journal-4355	500	1	solubletransforming	solubletransforme	VERB
american_scientific_journal-4355	500	2	growth	growth	NOUN
american_scientific_journal-4355	500	3	factor	factor	NOUN
american_scientific_journal-4355	500	4	-	-	PUNCT
american_scientific_journal-4355	500	5	beta	beta	NOUN
american_scientific_journal-4355	500	6	type	type	NOUN
american_scientific_journal-4355	500	7	iii	iii	NUM
american_scientific_journal-4355	500	8	receptor	receptor	NOUN
american_scientific_journal-4355	500	9	gene	gene	NOUN
american_scientific_journal-4355	500	10	transfection	transfection	NOUN
american_scientific_journal-4355	500	11	inhibits	inhibit	VERB
american_scientific_journal-4355	500	12	fibrous	fibrous	ADJ
american_scientific_journal-4355	500	13	airway	airway	NOUN
american_scientific_journal-4355	500	14	obliteration	obliteration	NOUN
american_scientific_journal-4355	500	15	in	in	ADP
american_scientific_journal-4355	500	16	a	a	DET
american_scientific_journal-4355	500	17	rat	rat	NOUN
american_scientific_journal-4355	500	18	model	model	NOUN
american_scientific_journal-4355	500	19	of	of	ADP
american_scientific_journal-4355	500	20	bronchiolitis	bronchiolitis	ADJ
american_scientific_journal-4355	500	21	obliterans	obliteran	NOUN
american_scientific_journal-4355	500	22	.	.	PUNCT
american_scientific_journal-4355	501	1	am	be	AUX
american_scientific_journal-4355	501	2	j	j	PROPN
american_scientific_journal-4355	501	3	respir	respir	NOUN
american_scientific_journal-4355	501	4	crit	crit	PROPN
american_scientific_journal-4355	501	5	care	care	NOUN
american_scientific_journal-4355	501	6	med	me	VERB
american_scientific_journal-4355	501	7	.	.	PUNCT
american_scientific_journal-4355	502	1	1.165(3):419[52	1.165(3):419[52	NUM
american_scientific_journal-4355	502	2	]	]	X
american_scientific_journal-4355	502	3	criswell	criswell	PROPN
american_scientific_journal-4355	502	4	t.l	t.l	PROPN
american_scientific_journal-4355	502	5	.	.	PROPN
american_scientific_journal-4355	502	6	,	,	PUNCT
american_scientific_journal-4355	502	7	dumont	dumont	PROPN
american_scientific_journal-4355	502	8	n.	n.	PROPN
american_scientific_journal-4355	502	9	,	,	PUNCT
american_scientific_journal-4355	502	10	joey	joey	PROPN
american_scientific_journal-4355	502	11	v.	v.	PROPN
american_scientific_journal-4355	502	12	,	,	PUNCT
american_scientific_journal-4355	502	13	barnett	barnett	PROPN
american_scientific_journal-4355	502	14	.	.	PUNCT
american_scientific_journal-4355	502	15	,	,	PUNCT
american_scientific_journal-4355	502	16	et	et	PROPN
american_scientific_journal-4355	502	17	al	al	PROPN
american_scientific_journal-4355	502	18	.	.	PUNCT
american_scientific_journal-4355	503	1	(	(	PUNCT
american_scientific_journal-4355	503	2	2008	2008	NUM
american_scientific_journal-4355	503	3	)	)	PUNCT
american_scientific_journal-4355	503	4	.	.	PUNCT
american_scientific_journal-4355	504	1	knockdown	knockdown	NOUN
american_scientific_journal-4355	504	2	of	of	ADP
american_scientific_journal-4355	504	3	the	the	DET
american_scientific_journal-4355	504	4	transforming	transform	VERB
american_scientific_journal-4355	504	5	growth	growth	NOUN
american_scientific_journal-4355	504	6	factor	factor	NOUN
american_scientific_journal-4355	504	7	-	-	PUNCT
american_scientific_journal-4355	504	8	β	β	NOUN
american_scientific_journal-4355	504	9	type	type	NOUN
american_scientific_journal-4355	504	10	iii	iii	NUM
american_scientific_journal-4355	504	11	receptor	receptor	NOUN
american_scientific_journal-4355	504	12	impairs	impair	VERB
american_scientific_journal-4355	504	13	motility	motility	NOUN
american_scientific_journal-4355	504	14	and	and	CCONJ
american_scientific_journal-4355	504	15	invasion	invasion	NOUN
american_scientific_journal-4355	504	16	of	of	ADP
american_scientific_journal-4355	504	17	metastatic	metastatic	ADJ
american_scientific_journal-4355	504	18	cancer	cancer	NOUN
american_scientific_journal-4355	504	19	6307	6307	NUM
american_scientific_journal-4355	504	20	.	.	PUNCT
american_scientific_journal-4355	505	1	cells	cell	NOUN
american_scientific_journal-4355	505	2	.	.	PUNCT
american_scientific_journal-4355	506	1	cancer	cancer	NOUN
american_scientific_journal-4355	506	2	res	re	NOUN
american_scientific_journal-4355	506	3	.	.	PUNCT
american_scientific_journal-4355	507	1	carlos	carlos	PROPN
american_scientific_journal-4355	507	2	l.	l.	PROPN
american_scientific_journal-4355	507	3	arteaga	arteaga	PROPN
american_scientific_journal-4355	507	4	,	,	PUNCT
american_scientific_journal-4355	507	5	division	division	NOUN
american_scientific_journal-4355	507	6	of	of	ADP
american_scientific_journal-4355	507	7	oncology	oncology	NOUN
american_scientific_journal-4355	507	8	,	,	PUNCT
american_scientific_journal-4355	507	9	vanderbilt	vanderbilt	PROPN
american_scientific_journal-4355	507	10	university	university	PROPN
american_scientific_journal-4355	507	11	medical	medical	ADJ
american_scientific_journal-4355	507	12	center	center	NOUN
american_scientific_journal-4355	507	13	,	,	PUNCT
american_scientific_journal-4355	507	14	tn	tn	PROPN
american_scientific_journal-4355	507	15	37232	37232	NUM
american_scientific_journal-4355	507	16	.	.	PUNCT
american_scientific_journal-4355	508	1	[	[	X
american_scientific_journal-4355	508	2	53	53	NUM
american_scientific_journal-4355	508	3	]	]	X
american_scientific_journal-4355	508	4	iwano	iwano	PROPN
american_scientific_journal-4355	508	5	m.	m.	NOUN
american_scientific_journal-4355	508	6	,	,	PUNCT
american_scientific_journal-4355	508	7	plieth	plieth	PROPN
american_scientific_journal-4355	508	8	d.	d.	PROPN
american_scientific_journal-4355	508	9	,	,	PUNCT
american_scientific_journal-4355	508	10	danoff	danoff	ADP
american_scientific_journal-4355	508	11	t.m	t.m	PROPN
american_scientific_journal-4355	508	12	.	.	PROPN
american_scientific_journal-4355	508	13	,	,	PUNCT
american_scientific_journal-4355	508	14	xue	xue	PROPN
american_scientific_journal-4355	508	15	c.	c.	PROPN
american_scientific_journal-4355	508	16	,	,	PUNCT
american_scientific_journal-4355	508	17	et	et	PROPN
american_scientific_journal-4355	508	18	al	al	PROPN
american_scientific_journal-4355	508	19	(	(	PUNCT
american_scientific_journal-4355	508	20	2002	2002	NUM
american_scientific_journal-4355	508	21	)	)	PUNCT
american_scientific_journal-4355	508	22	.	.	PUNCT
american_scientific_journal-4355	509	1	evidence	evidence	NOUN
american_scientific_journal-4355	509	2	that	that	SCONJ
american_scientific_journal-4355	509	3	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	509	4	derive	derive	VERB
american_scientific_journal-4355	509	5	from	from	ADP
american_scientific_journal-4355	509	6	epithelium	epithelium	NOUN
american_scientific_journal-4355	509	7	during	during	ADP
american_scientific_journal-4355	509	8	tissue	tissue	NOUN
american_scientific_journal-4355	509	9	fibrosis	fibrosis	NOUN
american_scientific_journal-4355	509	10	.	.	PUNCT
american_scientific_journal-4355	510	1	j	j	PROPN
american_scientific_journal-4355	510	2	clin	clin	PROPN
american_scientific_journal-4355	510	3	invest	invest	PROPN
american_scientific_journal-4355	510	4	,	,	PUNCT
american_scientific_journal-4355	510	5	110(3):341	110(3):341	NUM
american_scientific_journal-4355	510	6	-	-	SYM
american_scientific_journal-4355	510	7	350	350	NUM
american_scientific_journal-4355	510	8	[	[	X
american_scientific_journal-4355	510	9	54	54	NUM
american_scientific_journal-4355	510	10	]	]	PUNCT
american_scientific_journal-4355	510	11	bilandzic	bilandzic	PROPN
american_scientific_journal-4355	510	12	m.	m.	NOUN
american_scientific_journal-4355	510	13	,	,	PUNCT
american_scientific_journal-4355	510	14	chu	chu	PROPN
american_scientific_journal-4355	510	15	s.	s.	PROPN
american_scientific_journal-4355	510	16	,	,	PUNCT
american_scientific_journal-4355	510	17	farnworth	farnworth	PROPN
american_scientific_journal-4355	510	18	p.g	p.g	PROPN
american_scientific_journal-4355	510	19	.	.	PROPN
american_scientific_journal-4355	510	20	,	,	PUNCT
american_scientific_journal-4355	510	21	harrison	harrison	PROPN
american_scientific_journal-4355	510	22	c.	c.	PROPN
american_scientific_journal-4355	510	23	,et	,et	PUNCT
american_scientific_journal-4355	510	24	al	al	PROPN
american_scientific_journal-4355	510	25	.	.	PROPN
american_scientific_journal-4355	510	26	(	(	PUNCT
american_scientific_journal-4355	510	27	2009	2009	NUM
american_scientific_journal-4355	510	28	)	)	PUNCT
american_scientific_journal-4355	510	29	.	.	PUNCT
american_scientific_journal-4355	511	1	loss	loss	NOUN
american_scientific_journal-4355	511	2	of	of	ADP
american_scientific_journal-4355	511	3	betaglycan	betaglycan	PROPN
american_scientific_journal-4355	511	4	contributes	contribute	VERB
american_scientific_journal-4355	511	5	to	to	ADP
american_scientific_journal-4355	511	6	the	the	DET
american_scientific_journal-4355	511	7	malignant	malignant	ADJ
american_scientific_journal-4355	511	8	properties	property	NOUN
american_scientific_journal-4355	511	9	of	of	ADP
american_scientific_journal-4355	511	10	human	human	ADJ
american_scientific_journal-4355	511	11	granulosa	granulosa	NOUN
american_scientific_journal-4355	511	12	tumor	tumor	NOUN
american_scientific_journal-4355	511	13	cells	cell	NOUN
american_scientific_journal-4355	511	14	.	.	PUNCT
american_scientific_journal-4355	512	1	molecular	molecular	ADJ
american_scientific_journal-4355	512	2	endocrinology	endocrinology	NOUN
american_scientific_journal-4355	512	3	,	,	PUNCT
american_scientific_journal-4355	512	4	23(4):539	23(4):539	NOUN
american_scientific_journal-4355	512	5	-	-	SYM
american_scientific_journal-4355	512	6	548	548	NUM
american_scientific_journal-4355	512	7	.	.	PUNCT
american_scientific_journal-4355	513	1	[	[	X
american_scientific_journal-4355	513	2	55	55	NUM
american_scientific_journal-4355	513	3	]	]	X
american_scientific_journal-4355	513	4	willis	willis	PROPN
american_scientific_journal-4355	513	5	b.c	b.c	PROPN
american_scientific_journal-4355	513	6	.	.	PROPN
american_scientific_journal-4355	513	7	,	,	PUNCT
american_scientific_journal-4355	513	8	and	and	CCONJ
american_scientific_journal-4355	513	9	borok	borok	PROPN
american_scientific_journal-4355	513	10	z.	z.	PROPN
american_scientific_journal-4355	513	11	(	(	PUNCT
american_scientific_journal-4355	513	12	2007	2007	NUM
american_scientific_journal-4355	513	13	)	)	PUNCT
american_scientific_journal-4355	513	14	.	.	PUNCT
american_scientific_journal-4355	514	1	tgf	tgf	PROPN
american_scientific_journal-4355	514	2	-	-	PUNCT
american_scientific_journal-4355	514	3	beta	beta	NOUN
american_scientific_journal-4355	514	4	-	-	PUNCT
american_scientific_journal-4355	514	5	induced	induce	VERB
american_scientific_journal-4355	514	6	emt	emt	NOUN
american_scientific_journal-4355	514	7	:	:	PUNCT
american_scientific_journal-4355	514	8	mechanisms	mechanism	NOUN
american_scientific_journal-4355	514	9	and	and	CCONJ
american_scientific_journal-4355	514	10	implications	implication	NOUN
american_scientific_journal-4355	514	11	for	for	ADP
american_scientific_journal-4355	514	12	fibrotilung	fibrotilung	ADJ
american_scientific_journal-4355	514	13	disease	disease	NOUN
american_scientific_journal-4355	514	14	.	.	PUNCT
american_scientific_journal-4355	515	1	am	be	AUX
american_scientific_journal-4355	515	2	j	j	PROPN
american_scientific_journal-4355	515	3	physiol	physiol	PROPN
american_scientific_journal-4355	515	4	lung	lung	PROPN
american_scientific_journal-4355	515	5	cell	cell	NOUN
american_scientific_journal-4355	515	6	mol	mol	ADP
american_scientific_journal-4355	515	7	physiol	physiol	PROPN
american_scientific_journal-4355	515	8	293(3):l525	293(3):l525	PROPN
american_scientific_journal-4355	515	9	-	-	SYM
american_scientific_journal-4355	515	10	53	53	NUM
american_scientific_journal-4355	515	11	.	.	PUNCT
american_scientific_journal-4355	516	1	[	[	X
american_scientific_journal-4355	516	2	56	56	NUM
american_scientific_journal-4355	516	3	]	]	PUNCT
american_scientific_journal-4355	516	4	.	.	PUNCT
american_scientific_journal-4355	517	1	gatza	gatza	PROPN
american_scientific_journal-4355	518	1	c.e	c.e	PROPN
american_scientific_journal-4355	518	2	.	.	PROPN
american_scientific_journal-4355	518	3	,	,	PUNCT
american_scientific_journal-4355	518	4	oh	oh	INTJ
american_scientific_journal-4355	518	5	s.y	s.y	PROPN
american_scientific_journal-4355	518	6	.	.	PROPN
american_scientific_journal-4355	518	7	,	,	PUNCT
american_scientific_journal-4355	518	8	and	and	CCONJ
american_scientific_journal-4355	518	9	blobe	blobe	PROPN
american_scientific_journal-4355	518	10	g.c	g.c	PROPN
american_scientific_journal-4355	518	11	.	.	PROPN
american_scientific_journal-4355	518	12	(	(	PUNCT
american_scientific_journal-4355	518	13	2010	2010	NUM
american_scientific_journal-4355	518	14	)	)	PUNCT
american_scientific_journal-4355	518	15	.	.	PUNCT
american_scientific_journal-4355	519	1	roles	role	NOUN
american_scientific_journal-4355	519	2	for	for	ADP
american_scientific_journal-4355	519	3	the	the	DET
american_scientific_journal-4355	519	4	type	type	NOUN
american_scientific_journal-4355	519	5	iii	iii	PROPN
american_scientific_journal-4355	519	6	tgf	tgf	PROPN
american_scientific_journal-4355	519	7	-	-	PUNCT
american_scientific_journal-4355	519	8	beta	beta	NOUN
american_scientific_journal-4355	519	9	receptor	receptor	NOUN
american_scientific_journal-4355	519	10	in	in	ADP
american_scientific_journal-4355	519	11	human	human	ADJ
american_scientific_journal-4355	519	12	cancer	cancer	NOUN
american_scientific_journal-4355	519	13	cell	cell	NOUN
american_scientific_journal-4355	519	14	signal	signal	NOUN
american_scientific_journal-4355	519	15	.	.	PUNCT
american_scientific_journal-4355	520	1	22(8):1163	22(8):1163	NUM
american_scientific_journal-4355	520	2	-	-	SYM
american_scientific_journal-4355	520	3	74	74	NUM
american_scientific_journal-4355	520	4	.	.	PUNCT
american_scientific_journal-4355	521	1	[	[	X
american_scientific_journal-4355	521	2	57	57	NUM
american_scientific_journal-4355	521	3	]	]	PUNCT
american_scientific_journal-4355	521	4	.	.	PUNCT
american_scientific_journal-4355	522	1	jiang	jiang	PROPN
american_scientific_journal-4355	522	2	x.	x.	PROPN
american_scientific_journal-4355	522	3	,	,	PUNCT
american_scientific_journal-4355	522	4	liu	liu	PROPN
american_scientific_journal-4355	522	5	r.	r.	PROPN
american_scientific_journal-4355	522	6	,	,	PUNCT
american_scientific_journal-4355	522	7	lei	lei	PROPN
american_scientific_journal-4355	522	8	z.	z.	PROPN
american_scientific_journal-4355	522	9	,	,	PUNCT
american_scientific_journal-4355	522	10	you	you	PRON
american_scientific_journal-4355	522	11	j.	j.	PROPN
american_scientific_journal-4355	522	12	,	,	PUNCT
american_scientific_journal-4355	522	13	zhou	zhou	PROPN
american_scientific_journal-4355	522	14	q.	q.	PROPN
american_scientific_journal-4355	522	15	et	et	PROPN
american_scientific_journal-4355	522	16	al	al	PROPN
american_scientific_journal-4355	522	17	.	.	PROPN
american_scientific_journal-4355	522	18	(	(	PUNCT
american_scientific_journal-4355	522	19	2010	2010	NUM
american_scientific_journal-4355	522	20	)	)	PUNCT
american_scientific_journal-4355	522	21	.	.	PUNCT
american_scientific_journal-4355	523	1	defective	defective	ADJ
american_scientific_journal-4355	523	2	expression	expression	NOUN
american_scientific_journal-4355	523	3	of	of	ADP
american_scientific_journal-4355	523	4	tgfbr3	tgfbr3	PROPN
american_scientific_journal-4355	523	5	gene	gene	NOUN
american_scientific_journal-4355	523	6	and	and	CCONJ
american_scientific_journal-4355	523	7	its	its	PRON
american_scientific_journal-4355	523	8	molecular	molecular	ADJ
american_scientific_journal-4355	523	9	mechanisms	mechanism	NOUN
american_scientific_journal-4355	523	10	in	in	ADP
american_scientific_journal-4355	523	11	non	non	ADJ
american_scientific_journal-4355	523	12	-	-	ADJ
american_scientific_journal-4355	523	13	small	small	ADJ
american_scientific_journal-4355	523	14	cell	cell	NOUN
american_scientific_journal-4355	523	15	lung	lung	NOUN
american_scientific_journal-4355	523	16	cancer	cancer	NOUN
american_scientific_journal-4355	523	17	cell	cell	NOUN
american_scientific_journal-4355	523	18	lines	line	NOUN
american_scientific_journal-4355	523	19	.	.	PUNCT
american_scientific_journal-4355	524	1	13(5):451	13(5):451	X
american_scientific_journal-4355	524	2	-	-	SYM
american_scientific_journal-4355	524	3	7	7	NUM
american_scientific_journal-4355	524	4	.	.	PUNCT
american_scientific_journal-4355	525	1	[	[	X
american_scientific_journal-4355	525	2	58	58	NUM
american_scientific_journal-4355	525	3	]	]	PUNCT
american_scientific_journal-4355	525	4	.	.	PUNCT
american_scientific_journal-4355	526	1	hempel	hempel	PROPN
american_scientific_journal-4355	526	2	n.	n.	PROPN
american_scientific_journal-4355	526	3	,	,	PUNCT
american_scientific_journal-4355	526	4	how	how	SCONJ
american_scientific_journal-4355	526	5	t.	t.	PROPN
american_scientific_journal-4355	526	6	,	,	PUNCT
american_scientific_journal-4355	526	7	cooper	cooper	PROPN
american_scientific_journal-4355	526	8	s.j	s.j	PROPN
american_scientific_journal-4355	526	9	.	.	PROPN
american_scientific_journal-4355	526	10	,	,	PUNCT
american_scientific_journal-4355	526	11	green	green	PROPN
american_scientific_journal-4355	526	12	t.r	t.r	PROPN
american_scientific_journal-4355	526	13	.	.	PROPN
american_scientific_journal-4355	526	14	,	,	PUNCT
american_scientific_journal-4355	526	15	et	et	PROPN
american_scientific_journal-4355	526	16	al	al	PROPN
american_scientific_journal-4355	526	17	(	(	PUNCT
american_scientific_journal-4355	526	18	2008	2008	NUM
american_scientific_journal-4355	526	19	)	)	PUNCT
american_scientific_journal-4355	526	20	.	.	PUNCT
american_scientific_journal-4355	527	1	expression	expression	NOUN
american_scientific_journal-4355	527	2	of	of	ADP
american_scientific_journal-4355	527	3	the	the	DET
american_scientific_journal-4355	527	4	type	type	NOUN
american_scientific_journal-4355	527	5	iii	iii	PROPN
american_scientific_journal-4355	527	6	tgf	tgf	PROPN
american_scientific_journal-4355	527	7	-	-	PUNCT
american_scientific_journal-4355	527	8	β	β	NOUN
american_scientific_journal-4355	527	9	receptor	receptor	NOUN
american_scientific_journal-4355	527	10	is	be	AUX
american_scientific_journal-4355	527	11	negatively	negatively	ADV
american_scientific_journal-4355	527	12	regulated	regulate	VERB
american_scientific_journal-4355	527	13	by	by	ADP
american_scientific_journal-4355	527	14	tgf	tgf	PROPN
american_scientific_journal-4355	527	15	-	-	PUNCT
american_scientific_journal-4355	527	16	β	β	NOUN
american_scientific_journal-4355	527	17	.	.	PUNCT
american_scientific_journal-4355	528	1	carcinogenesis	carcinogenesis	NOUN
american_scientific_journal-4355	528	2	,	,	PUNCT
american_scientific_journal-4355	528	3	29(5):905	29(5):905	NUM
american_scientific_journal-4355	528	4	-	-	PUNCT
american_scientific_journal-4355	528	5	912	912	NUM
american_scientific_journal-4355	528	6	.	.	PUNCT
american_scientific_journal-4355	529	1	[	[	X
american_scientific_journal-4355	529	2	59	59	NUM
american_scientific_journal-4355	529	3	]	]	PUNCT
american_scientific_journal-4355	529	4	.	.	PUNCT
american_scientific_journal-4355	530	1	dong	dong	PROPN
american_scientific_journal-4355	530	2	m.	m.	NOUN
american_scientific_journal-4355	530	3	,	,	PUNCT
american_scientific_journal-4355	530	4	how	how	SCONJ
american_scientific_journal-4355	530	5	t.	t.	PROPN
american_scientific_journal-4355	530	6	,	,	PUNCT
american_scientific_journal-4355	530	7	kirkbride	kirkbride	PROPN
american_scientific_journal-4355	530	8	k.c	k.c	PROPN
american_scientific_journal-4355	530	9	.	.	PROPN
american_scientific_journal-4355	530	10	,	,	PUNCT
american_scientific_journal-4355	530	11	et	et	PROPN
american_scientific_journal-4355	530	12	al	al	PROPN
american_scientific_journal-4355	530	13	.	.	PUNCT
american_scientific_journal-4355	531	1	(	(	PUNCT
american_scientific_journal-4355	531	2	2007)the	2007)the	DET
american_scientific_journal-4355	531	3	type	type	NOUN
american_scientific_journal-4355	531	4	iii	iii	PROPN
american_scientific_journal-4355	531	5	tgf	tgf	PROPN
american_scientific_journal-4355	531	6	-	-	PUNCT
american_scientific_journal-4355	531	7	ß	ß	NOUN
american_scientific_journal-4355	531	8	receptor	receptor	NOUN
american_scientific_journal-4355	531	9	suppresses	suppress	VERB
american_scientific_journal-4355	531	10	breast	breast	NOUN
american_scientific_journal-4355	531	11	cancer	cancer	NOUN
american_scientific_journal-4355	531	12	progression	progression	NOUN
american_scientific_journal-4355	531	13	.	.	PUNCT
american_scientific_journal-4355	532	1	j	j	PROPN
american_scientific_journal-4355	532	2	clin	clin	PROPN
american_scientific_journal-4355	532	3	invest;117:206	invest;117:206	PROPN
american_scientific_journal-4355	532	4	-	-	PUNCT
american_scientific_journal-4355	532	5	17	17	NUM
american_scientific_journal-4355	532	6	.	.	PUNCT
american_scientific_journal-4355	533	1	[	[	X
american_scientific_journal-4355	533	2	60	60	NUM
american_scientific_journal-4355	533	3	]	]	PUNCT
american_scientific_journal-4355	533	4	.	.	PUNCT
american_scientific_journal-4355	534	1	criswell	criswell	PROPN
american_scientific_journal-4355	534	2	t.l	t.l	PROPN
american_scientific_journal-4355	534	3	.	.	PROPN
american_scientific_journal-4355	534	4	,	,	PUNCT
american_scientific_journal-4355	534	5	dumont	dumont	PROPN
american_scientific_journal-4355	534	6	n.	n.	PROPN
american_scientific_journal-4355	534	7	,	,	PUNCT
american_scientific_journal-4355	534	8	joey	joey	PROPN
american_scientific_journal-4355	534	9	v.	v.	PROPN
american_scientific_journal-4355	534	10	,	,	PUNCT
american_scientific_journal-4355	534	11	barnett	barnett	PROPN
american_scientific_journal-4355	534	12	.	.	PUNCT
american_scientific_journal-4355	534	13	,et	,et	PUNCT
american_scientific_journal-4355	535	1	al	al	PROPN
american_scientific_journal-4355	535	2	.	.	PROPN
american_scientific_journal-4355	535	3	(	(	PUNCT
american_scientific_journal-4355	535	4	2008	2008	NUM
american_scientific_journal-4355	535	5	)	)	PUNCT
american_scientific_journal-4355	535	6	.	.	PUNCT
american_scientific_journal-4355	536	1	knockdown	knockdown	NOUN
american_scientific_journal-4355	536	2	of	of	ADP
american_scientific_journal-4355	536	3	transforming	transform	VERB
american_scientific_journal-4355	536	4	growth	growth	NOUN
american_scientific_journal-4355	536	5	factor	factor	NOUN
american_scientific_journal-4355	536	6	-	-	PUNCT
american_scientific_journal-4355	536	7	β	β	NOUN
american_scientific_journal-4355	536	8	type	type	NOUN
american_scientific_journal-4355	536	9	iii	iii	NUM
american_scientific_journal-4355	536	10	receptor	receptor	NOUN
american_scientific_journal-4355	536	11	impairs	impair	VERB
american_scientific_journal-4355	536	12	motility	motility	NOUN
american_scientific_journal-4355	536	13	and	and	CCONJ
american_scientific_journal-4355	536	14	invasion	invasion	NOUN
american_scientific_journal-4355	536	15	of	of	ADP
american_scientific_journal-4355	536	16	metastatic	metastatic	ADJ
american_scientific_journal-4355	536	17	cancer	cancer	NOUN
american_scientific_journal-4355	536	18	cells	cell	NOUN
american_scientific_journal-4355	536	19	.	.	PUNCT
american_scientific_journal-4355	537	1	cancer	cancer	NOUN
american_scientific_journal-4355	537	2	res	re	NOUN
american_scientific_journal-4355	537	3	.	.	PUNCT
american_scientific_journal-4355	538	1	carlos	carlos	PROPN
american_scientific_journal-4355	538	2	l.	l.	PROPN
american_scientific_journal-4355	538	3	arteaga	arteaga	PROPN
american_scientific_journal-4355	538	4	,	,	PUNCT
american_scientific_journal-4355	538	5	division	division	NOUN
american_scientific_journal-4355	538	6	of	of	ADP
american_scientific_journal-4355	538	7	oncology	oncology	NOUN
american_scientific_journal-4355	538	8	,	,	PUNCT
american_scientific_journal-4355	538	9	vanderbilt	vanderbilt	PROPN
american_scientific_journal-4355	538	10	university	university	PROPN
american_scientific_journal-4355	538	11	medical	medical	ADJ
american_scientific_journal-4355	538	12	center	center	NOUN
american_scientific_journal-4355	538	13	,	,	PUNCT
american_scientific_journal-4355	538	14	tn37232	tn37232	PROPN
american_scientific_journal-4355	538	15	-	-	PUNCT
american_scientific_journal-4355	538	16	6307	6307	NUM
american_scientific_journal-4355	538	17	.	.	PUNCT
american_scientific_journal-4355	539	1	[	[	X
american_scientific_journal-4355	539	2	61	61	NUM
american_scientific_journal-4355	539	3	]	]	PUNCT
american_scientific_journal-4355	539	4	.	.	PUNCT
american_scientific_journal-4355	540	1	mythreye	mythreye	NOUN
american_scientific_journal-4355	540	2	k	k	PROPN
american_scientific_journal-4355	540	3	and	and	CCONJ
american_scientific_journal-4355	540	4	blobe	blobe	PROPN
american_scientific_journal-4355	540	5	g.c	g.c	PROPN
american_scientific_journal-4355	540	6	.	.	PROPN
american_scientific_journal-4355	540	7	(	(	PUNCT
american_scientific_journal-4355	540	8	2009	2009	NUM
american_scientific_journal-4355	540	9	)	)	PUNCT
american_scientific_journal-4355	541	1	.the	.the	DET
american_scientific_journal-4355	541	2	type	type	NOUN
american_scientific_journal-4355	541	3	iii	iii	NUM
american_scientific_journal-4355	541	4	tgfbeta	tgfbeta	NOUN
american_scientific_journal-4355	541	5	receptor	receptor	NOUN
american_scientific_journal-4355	541	6	regulates	regulate	VERB
american_scientific_journal-4355	541	7	directional	directional	ADJ
american_scientific_journal-4355	541	8	migration	migration	NOUN
american_scientific_journal-4355	541	9	:	:	PUNCT
american_scientific_journal-4355	541	10	new	new	ADJ
american_scientific_journal-4355	541	11	tricks	trick	NOUN
american_scientific_journal-4355	541	12	for	for	ADP
american_scientific_journal-4355	541	13	an	an	DET
american_scientific_journal-4355	541	14	old	old	ADJ
american_scientific_journal-4355	541	15	dog	dog	NOUN
american_scientific_journal-4355	541	16	.	.	PUNCT
american_scientific_journal-4355	542	1	cell	cell	NOUN
american_scientific_journal-4355	542	2	cycle	cycle	NOUN
american_scientific_journal-4355	542	3	.	.	PUNCT
american_scientific_journal-4355	543	1	8(19):3069	8(19):3069	NUM
american_scientific_journal-4355	543	2	-	-	SYM
american_scientific_journal-4355	543	3	70	70	NUM
american_scientific_journal-4355	543	4	.	.	PUNCT
american_scientific_journal-4355	544	1	epub2009	epub2009	PROPN
american_scientific_journal-4355	544	2	oct	oct	PROPN
american_scientific_journal-4355	544	3	8	8	NUM
american_scientific_journal-4355	544	4	.	.	PUNCT
american_scientific_journal-4355	545	1	[	[	X
american_scientific_journal-4355	545	2	62	62	NUM
american_scientific_journal-4355	545	3	]	]	PUNCT
american_scientific_journal-4355	545	4	.	.	PUNCT
american_scientific_journal-4355	546	1	dong	dong	PROPN
american_scientific_journal-4355	546	2	m.	m.	NOUN
american_scientific_journal-4355	546	3	,	,	PUNCT
american_scientific_journal-4355	546	4	how	how	SCONJ
american_scientific_journal-4355	546	5	t.	t.	PROPN
american_scientific_journal-4355	546	6	,	,	PUNCT
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american_scientific_journal-4355	546	8	k.c	k.c	PROPN
american_scientific_journal-4355	546	9	.	.	PROPN
american_scientific_journal-4355	546	10	,	,	PUNCT
american_scientific_journal-4355	546	11	et	et	PROPN
american_scientific_journal-4355	546	12	al	al	PROPN
american_scientific_journal-4355	546	13	.	.	PUNCT
american_scientific_journal-4355	547	1	(	(	PUNCT
american_scientific_journal-4355	547	2	2007)the	2007)the	DET
american_scientific_journal-4355	547	3	type	type	NOUN
american_scientific_journal-4355	547	4	iii	iii	PROPN
american_scientific_journal-4355	547	5	tgf	tgf	PROPN
american_scientific_journal-4355	547	6	-	-	PUNCT
american_scientific_journal-4355	547	7	ß	ß	NOUN
american_scientific_journal-4355	547	8	receptor	receptor	NOUN
american_scientific_journal-4355	547	9	suppresses	suppress	VERB
american_scientific_journal-4355	547	10	breast	breast	NOUN
american_scientific_journal-4355	547	11	cancer	cancer	NOUN
american_scientific_journal-4355	547	12	progression	progression	NOUN
american_scientific_journal-4355	547	13	.	.	PUNCT
american_scientific_journal-4355	548	1	j	j	PROPN
american_scientific_journal-4355	548	2	clin	clin	PROPN
american_scientific_journal-4355	548	3	invest;117:206	invest;117:206	PROPN
american_scientific_journal-4355	548	4	-	-	PUNCT
american_scientific_journal-4355	548	5	17	17	NUM
american_scientific_journal-4355	548	6	.	.	PUNCT
american_scientific_journal-4355	549	1	[	[	X
american_scientific_journal-4355	549	2	63	63	NUM
american_scientific_journal-4355	549	3	]	]	PUNCT
american_scientific_journal-4355	549	4	.	.	PUNCT
american_scientific_journal-4355	550	1	chen	chen	PROPN
american_scientific_journal-4355	550	2	c.l	c.l	PROPN
american_scientific_journal-4355	550	3	.	.	PROPN
american_scientific_journal-4355	550	4	,	,	PUNCT
american_scientific_journal-4355	550	5	huang	huang	PROPN
american_scientific_journal-4355	550	6	s.s	s.s	PROPN
american_scientific_journal-4355	550	7	.	.	PROPN
american_scientific_journal-4355	550	8	,	,	PUNCT
american_scientific_journal-4355	550	9	and	and	CCONJ
american_scientific_journal-4355	550	10	huang	huang	PROPN
american_scientific_journal-4355	550	11	j.s	j.s	PROPN
american_scientific_journal-4355	550	12	.	.	PUNCT
american_scientific_journal-4355	550	13	(	(	PUNCT
american_scientific_journal-4355	550	14	2006	2006	NUM
american_scientific_journal-4355	550	15	)	)	PUNCT
american_scientific_journal-4355	550	16	.	.	PUNCT
american_scientific_journal-4355	551	1	cellular	cellular	ADJ
american_scientific_journal-4355	551	2	heparan	heparan	ADJ
american_scientific_journal-4355	551	3	sulfate	sulfate	NOUN
american_scientific_journal-4355	551	4	negatively	negatively	ADV
american_scientific_journal-4355	551	5	modulatetransforming	modulatetransforme	VERB
american_scientific_journal-4355	551	6	growth	growth	NOUN
american_scientific_journal-4355	551	7	factor	factor	NOUN
american_scientific_journal-4355	551	8	-	-	PUNCT
american_scientific_journal-4355	551	9	beta1	beta1	NOUN
american_scientific_journal-4355	551	10	(	(	PUNCT
american_scientific_journal-4355	551	11	tgf	tgf	NOUN
american_scientific_journal-4355	551	12	-	-	PUNCT
american_scientific_journal-4355	551	13	beta1	beta1	NOUN
american_scientific_journal-4355	551	14	)	)	PUNCT
american_scientific_journal-4355	551	15	responsiveness	responsiveness	NOUN
american_scientific_journal-4355	551	16	in	in	ADP
american_scientific_journal-4355	551	17	epithelial	epithelial	ADJ
american_scientific_journal-4355	551	18	cells	cell	NOUN
american_scientific_journal-4355	551	19	.	.	PUNCT
american_scientific_journal-4355	552	1	j	j	PROPN
american_scientific_journal-4355	552	2	biol	biol	PROPN
american_scientific_journal-4355	552	3	chem	chem	NOUN
american_scientific_journal-4355	552	4	.	.	PUNCT
american_scientific_journal-4355	553	1	28;281(17):11506	28;281(17):11506	NUM
american_scientific_journal-4355	553	2	-	-	SYM
american_scientific_journal-4355	553	3	14	14	NUM
american_scientific_journal-4355	553	4	.	.	PUNCT
american_scientific_journal-4355	554	1	[	[	X
american_scientific_journal-4355	554	2	64	64	NUM
american_scientific_journal-4355	554	3	]	]	PUNCT
american_scientific_journal-4355	554	4	.	.	PUNCT
american_scientific_journal-4355	555	1	juárez	juárez	PROPN
american_scientific_journal-4355	555	2	p.	p.	PROPN
american_scientific_journal-4355	555	3	,	,	PUNCT
american_scientific_journal-4355	555	4	vilchis	vilchis	ADJ
american_scientific_journal-4355	555	5	-	-	PUNCT
american_scientific_journal-4355	555	6	landeros	landero	NOUN
american_scientific_journal-4355	555	7	m.m	m.m	PROPN
american_scientific_journal-4355	555	8	.	.	PROPN
american_scientific_journal-4355	555	9	,	,	PUNCT
american_scientific_journal-4355	555	10	ponce	ponce	PROPN
american_scientific_journal-4355	555	11	-	-	PUNCT
american_scientific_journal-4355	555	12	coria	coria	PROPN
american_scientific_journal-4355	555	13	j.	j.	PROPN
american_scientific_journal-4355	555	14	,	,	PUNCT
american_scientific_journal-4355	556	1	mendoza	mendoza	PROPN
american_scientific_journal-4355	556	2	v.	v.	PROPN
american_scientific_journal-4355	556	3	,et	,et	PUNCT
american_scientific_journal-4355	556	4	a.l	a.l	X
american_scientific_journal-4355	556	5	(	(	PUNCT
american_scientific_journal-4355	556	6	2006	2006	NUM
american_scientific_journal-4355	556	7	)	)	PUNCT
american_scientific_journal-4355	556	8	,	,	PUNCT
american_scientific_journal-4355	556	9	(	(	PUNCT
american_scientific_journal-4355	556	10	soluble	soluble	ADJ
american_scientific_journal-4355	556	11	betaglycan	betaglycan	NOUN
american_scientific_journal-4355	556	12	reduces	reduce	VERB
american_scientific_journal-4355	556	13	renal	renal	ADJ
american_scientific_journal-4355	556	14	damage	damage	NOUN
american_scientific_journal-4355	556	15	progression	progression	NOUN
american_scientific_journal-4355	556	16	in	in	ADP
american_scientific_journal-4355	556	17	db	db	PROPN
american_scientific_journal-4355	556	18	/	/	SYM
american_scientific_journal-4355	556	19	db	db	PROPN
american_scientific_journal-4355	556	20	.	.	PROPN
american_scientific_journal-4355	556	21	am	be	AUX
american_scientific_journal-4355	556	22	j	j	PROPN
american_scientific_journal-4355	556	23	physiol	physiol	PROPN
american_scientific_journal-4355	556	24	renal	renal	PROPN
american_scientific_journal-4355	556	25	physiol	physiol	PROPN
american_scientific_journal-4355	556	26	292	292	NUM
american_scientific_journal-4355	556	27	:	:	PUNCT
american_scientific_journal-4355	556	28	f321	f321	ADJ
american_scientific_journal-4355	557	1	-	-	ADJ
american_scientific_journal-4355	557	2	f32	f32	NOUN
american_scientific_journal-4355	557	3	[	[	X
american_scientific_journal-4355	557	4	65	65	NUM
american_scientific_journal-4355	557	5	]	]	PUNCT
american_scientific_journal-4355	557	6	.	.	PUNCT
american_scientific_journal-4355	558	1	criswell	criswell	PROPN
american_scientific_journal-4355	558	2	t.l	t.l	PROPN
american_scientific_journal-4355	558	3	.	.	PROPN
american_scientific_journal-4355	558	4	,	,	PUNCT
american_scientific_journal-4355	558	5	dumont	dumont	PROPN
american_scientific_journal-4355	558	6	n.	n.	PROPN
american_scientific_journal-4355	558	7	,	,	PUNCT
american_scientific_journal-4355	558	8	joey	joey	PROPN
american_scientific_journal-4355	558	9	v.	v.	PROPN
american_scientific_journal-4355	558	10	,	,	PUNCT
american_scientific_journal-4355	558	11	barnett	barnett	PROPN
american_scientific_journal-4355	558	12	.	.	PUNCT
american_scientific_journal-4355	558	13	,et	,et	PUNCT
american_scientific_journal-4355	559	1	al	al	PROPN
american_scientific_journal-4355	559	2	.	.	PROPN
american_scientific_journal-4355	559	3	(	(	PUNCT
american_scientific_journal-4355	559	4	2008	2008	NUM
american_scientific_journal-4355	559	5	)	)	PUNCT
american_scientific_journal-4355	559	6	.	.	PUNCT
american_scientific_journal-4355	560	1	knockdown	knockdown	NOUN
american_scientific_journal-4355	560	2	of	of	ADP
american_scientific_journal-4355	560	3	the	the	DET
american_scientific_journal-4355	560	4	transforming	transform	VERB
american_scientific_journal-4355	560	5	growth	growth	NOUN
american_scientific_journal-4355	560	6	factor	factor	NOUN
american_scientific_journal-4355	560	7	-	-	PUNCT
american_scientific_journal-4355	560	8	β	β	NOUN
american_scientific_journal-4355	560	9	type	type	NOUN
american_scientific_journal-4355	560	10	iii	iii	NUM
american_scientific_journal-4355	560	11	receptor	receptor	NOUN
american_scientific_journal-4355	560	12	impairs	impair	VERB
american_scientific_journal-4355	560	13	motility	motility	NOUN
american_scientific_journal-4355	560	14	and	and	CCONJ
american_scientific_journal-4355	560	15	invasion	invasion	NOUN
american_scientific_journal-4355	560	16	of	of	ADP
american_scientific_journal-4355	560	17	metastatic	metastatic	ADJ
american_scientific_journal-4355	560	18	cancer	cancer	NOUN
american_scientific_journal-4355	560	19	cells	cell	NOUN
american_scientific_journal-4355	560	20	.	.	PUNCT
american_scientific_journal-4355	561	1	cancer	cancer	NOUN
american_scientific_journal-4355	561	2	res	re	NOUN
american_scientific_journal-4355	561	3	.	.	PUNCT
american_scientific_journal-4355	562	1	carlos	carlos	PROPN
american_scientific_journal-4355	562	2	l.	l.	PROPN
american_scientific_journal-4355	562	3	arteaga	arteaga	PROPN
american_scientific_journal-4355	562	4	,	,	PUNCT
american_scientific_journal-4355	562	5	division	division	NOUN
american_scientific_journal-4355	562	6	of	of	ADP
american_scientific_journal-4355	562	7	oncology	oncology	NOUN
american_scientific_journal-4355	562	8	,	,	PUNCT
american_scientific_journal-4355	562	9	vanderbilt	vanderbilt	PROPN
american_scientific_journal-4355	562	10	university	university	PROPN
american_scientific_journal-4355	562	11	medical	medical	ADJ
american_scientific_journal-4355	562	12	center	center	NOUN
american_scientific_journal-4355	562	13	,	,	PUNCT
american_scientific_journal-4355	562	14	tn	tn	PROPN
american_scientific_journal-4355	562	15	37232	37232	NUM
american_scientific_journal-4355	562	16	-	-	SYM
american_scientific_journal-4355	562	17	6307	6307	NUM
american_scientific_journal-4355	562	18	.	.	PUNCT
american_scientific_journal-4355	563	1	[	[	X
american_scientific_journal-4355	563	2	66	66	NUM
american_scientific_journal-4355	563	3	]	]	PUNCT
american_scientific_journal-4355	563	4	.	.	PUNCT
american_scientific_journal-4355	564	1	thiery	thiery	PROPN
american_scientific_journal-4355	564	2	j.p	j.p	PROPN
american_scientific_journal-4355	564	3	.	.	PROPN
american_scientific_journal-4355	564	4	,and	,and	PUNCT
american_scientific_journal-4355	564	5	sleeman	sleeman	PROPN
american_scientific_journal-4355	564	6	j.p	j.p	PROPN
american_scientific_journal-4355	564	7	.	.	PROPN
american_scientific_journal-4355	564	8	(	(	PUNCT
american_scientific_journal-4355	564	9	2006	2006	NUM
american_scientific_journal-4355	564	10	)	)	PUNCT
american_scientific_journal-4355	564	11	.	.	PUNCT
american_scientific_journal-4355	565	1	complex	complex	ADJ
american_scientific_journal-4355	565	2	networks	network	NOUN
american_scientific_journal-4355	565	3	orchestrate	orchestrate	VERB
american_scientific_journal-4355	565	4	epithelial	epithelial	ADJ
american_scientific_journal-4355	565	5	-	-	PUNCT
american_scientific_journal-4355	565	6	mesenchymal	mesenchymal	ADJ
american_scientific_journal-4355	565	7	transitions	transition	NOUN
american_scientific_journal-4355	565	8	.	.	PUNCT
american_scientific_journal-4355	566	1	nat	nat	PROPN
american_scientific_journal-4355	566	2	rev	rev	VERB
american_scientific_journal-4355	566	3	mol	mol	ADP
american_scientific_journal-4355	566	4	cell	cell	NOUN
american_scientific_journal-4355	566	5	biol	biol	NOUN
american_scientific_journal-4355	566	6	7(2):131	7(2):131	PROPN
american_scientific_journal-4355	566	7	-	-	SYM
american_scientific_journal-4355	566	8	142	142	NUM
american_scientific_journal-4355	566	9	.	.	PUNCT
american_scientific_journal-4355	567	1	[	[	X
american_scientific_journal-4355	567	2	67	67	NUM
american_scientific_journal-4355	567	3	]	]	PUNCT
american_scientific_journal-4355	567	4	.	.	PUNCT
american_scientific_journal-4355	568	1	gotzmann	gotzmann	PROPN
american_scientific_journal-4355	568	2	j.	j.	PROPN
american_scientific_journal-4355	568	3	,	,	PUNCT
american_scientific_journal-4355	568	4	mikula	mikula	ADJ
american_scientific_journal-4355	568	5	m.	m.	NOUN
american_scientific_journal-4355	568	6	,	,	PUNCT
american_scientific_journal-4355	568	7	eger	eger	PROPN
american_scientific_journal-4355	568	8	a.	a.	PROPN
american_scientific_journal-4355	568	9	,	,	PUNCT
american_scientific_journal-4355	568	10	schulte	schulte	PROPN
american_scientific_journal-4355	568	11	-	-	PUNCT
american_scientific_journal-4355	568	12	hermann	hermann	PROPN
american_scientific_journal-4355	568	13	r.	r.	PROPN
american_scientific_journal-4355	568	14	,et	,et	PUNCT
american_scientific_journal-4355	568	15	al	al	PROPN
american_scientific_journal-4355	568	16	.	.	PROPN
american_scientific_journal-4355	568	17	molecular	molecular	ADJ
american_scientific_journal-4355	568	18	aspects	aspect	NOUN
american_scientific_journal-4355	568	19	of	of	ADP
american_scientific_journal-4355	568	20	epithelial	epithelial	ADJ
american_scientific_journal-4355	568	21	cell	cell	NOUN
american_scientific_journal-4355	568	22	plasticity	plasticity	NOUN
american_scientific_journal-4355	568	23	:	:	PUNCT
american_scientific_journal-4355	568	24	implications	implication	NOUN
american_scientific_journal-4355	568	25	for	for	ADP
american_scientific_journal-4355	568	26	local	local	ADJ
american_scientific_journal-4355	568	27	tumor	tumor	NOUN
american_scientific_journal-4355	568	28	invasion	invasion	NOUN
american_scientific_journal-4355	568	29	and	and	CCONJ
american_scientific_journal-4355	568	30	metastasis	metastasis	NOUN
american_scientific_journal-4355	568	31	.	.	PUNCT
american_scientific_journal-4355	569	1	mutat	mutat	ADJ
american_scientific_journal-4355	569	2	res	re	NOUN
american_scientific_journal-4355	569	3	566(1):9	566(1):9	PROPN
american_scientific_journal-4355	569	4	-	-	PUNCT
american_scientific_journal-4355	569	5	20	20	NUM
american_scientific_journal-4355	569	6	.	.	PUNCT
american_scientific_journal-4355	570	1	[	[	X
american_scientific_journal-4355	570	2	68	68	NUM
american_scientific_journal-4355	570	3	]	]	PUNCT
american_scientific_journal-4355	570	4	.	.	PUNCT
american_scientific_journal-4355	571	1	evans	evans	PROPN
american_scientific_journal-4355	571	2	r.a	r.a	PROPN
american_scientific_journal-4355	571	3	,	,	PUNCT
american_scientific_journal-4355	571	4	tian	tian	PROPN
american_scientific_journal-4355	571	5	y.c	y.c	PROPN
american_scientific_journal-4355	571	6	.	.	PROPN
american_scientific_journal-4355	571	7	,	,	PUNCT
american_scientific_journal-4355	571	8	steadman	steadman	PROPN
american_scientific_journal-4355	571	9	r.	r.	PROPN
american_scientific_journal-4355	571	10	,	,	PUNCT
american_scientific_journal-4355	571	11	phillips	phillips	PROPN
american_scientific_journal-4355	571	12	a.o	a.o	PROPN
american_scientific_journal-4355	571	13	.	.	PROPN
american_scientific_journal-4355	571	14	(	(	PUNCT
american_scientific_journal-4355	571	15	2003).tgf	2003).tgf	NUM
american_scientific_journal-4355	571	16	-	-	PUNCT
american_scientific_journal-4355	571	17	β1	β1	NOUN
american_scientific_journal-4355	571	18	-	-	PUNCT
american_scientific_journal-4355	571	19	mediated	mediate	VERB
american_scientific_journal-4355	571	20	fibroblast	fibroblast	ADJ
american_scientific_journal-4355	571	21	-	-	PUNCT
american_scientific_journal-4355	571	22	myofibroblast	myofibroblast	NOUN
american_scientific_journal-4355	571	23	terminal	terminal	ADJ
american_scientific_journal-4355	571	24	differentiation	differentiation	NOUN
american_scientific_journal-4355	571	25	-	-	PUNCT
american_scientific_journal-4355	571	26	the	the	DET
american_scientific_journal-4355	571	27	role	role	NOUN
american_scientific_journal-4355	571	28	of	of	ADP
american_scientific_journal-4355	571	29	smad	smad	ADJ
american_scientific_journal-4355	571	30	proteins	protein	NOUN
american_scientific_journal-4355	571	31	.	.	PUNCT
american_scientific_journal-4355	572	1	exp	exp	NOUN
american_scientific_journal-4355	572	2	cell	cell	NOUN
american_scientific_journal-4355	572	3	res	re	NOUN
american_scientific_journal-4355	572	4	.282:90	.282:90	NOUN
american_scientific_journal-4355	572	5	-	-	PUNCT
american_scientific_journal-4355	572	6	100	100	NUM
american_scientific_journal-4355	572	7	.	.	PUNCT
american_scientific_journal-4355	573	1	[	[	X
american_scientific_journal-4355	573	2	69	69	NUM
american_scientific_journal-4355	573	3	]	]	PUNCT
american_scientific_journal-4355	573	4	.	.	PUNCT
american_scientific_journal-4355	574	1	simpson	simpson	PROPN
american_scientific_journal-4355	574	2	r.m.l	r.m.l	PROPN
american_scientific_journal-4355	574	3	.	.	PROPN
american_scientific_journal-4355	574	4	,	,	PUNCT
american_scientific_journal-4355	574	5	stephens	stephens	PROPN
american_scientific_journal-4355	574	6	p.	p.	PROPN
american_scientific_journal-4355	574	7	,	,	PUNCT
american_scientific_journal-4355	574	8	steadman	steadman	PROPN
american_scientific_journal-4355	574	9	r.	r.	PROPN
american_scientific_journal-4355	574	10	,	,	PUNCT
american_scientific_journal-4355	574	11	and	and	CCONJ
american_scientific_journal-4355	574	12	phillips	phillips	PROPN
american_scientific_journal-4355	574	13	a.	a.	NOUN
american_scientific_journal-4355	574	14	(	(	PUNCT
american_scientific_journal-4355	574	15	2010	2010	NUM
american_scientific_journal-4355	574	16	)	)	PUNCT
american_scientific_journal-4355	574	17	.	.	PUNCT
american_scientific_journal-4355	575	1	aging	age	VERB
american_scientific_journal-4355	575	2	fibroblasts	fibroblast	NOUN
american_scientific_journal-4355	575	3	resistphenotypic	resistphenotypic	NOUN
american_scientific_journal-4355	575	4	maturation	maturation	NOUN
american_scientific_journal-4355	575	5	because	because	SCONJ
american_scientific_journal-4355	575	6	of	of	ADP
american_scientific_journal-4355	575	7	impaired	impaired	ADJ
american_scientific_journal-4355	575	8	hyaluronan	hyaluronan	NOUN
american_scientific_journal-4355	575	9	-	-	PUNCT
american_scientific_journal-4355	575	10	dependent	dependent	ADJ
american_scientific_journal-4355	575	11	cd44	cd44	PROPN
american_scientific_journal-4355	575	12	/	/	SYM
american_scientific_journal-4355	575	13	epidermal	epidermal	ADJ
american_scientific_journal-4355	575	14	growth	growth	NOUN
american_scientific_journal-4355	575	15	factor	factor	NOUN
american_scientific_journal-4355	575	16	receptor	receptor	NOUN
american_scientific_journal-4355	575	17	signaling	signal	VERB
american_scientific_journal-4355	575	18	.	.	PUNCT
american_scientific_journal-4355	576	1	american	american	ADJ
american_scientific_journal-4355	576	2	journal	journal	PROPN
american_scientific_journal-4355	576	3	of	of	ADP
american_scientific_journal-4355	576	4	pathology	pathology	PROPN
american_scientific_journal-4355	576	5	.	.	PUNCT
american_scientific_journal-4355	577	1	176:1215	176:1215	X
american_scientific_journal-4355	577	2	-	-	PUNCT
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american_scientific_journal-4355	577	4	.	.	PUNCT
american_scientific_journal-4355	578	1	0.1	0.1	NUM
american_scientific_journal-4355	578	2	0.1	0.1	NUM
american_scientific_journal-4355	578	3	0.2	0.2	NUM
american_scientific_journal-4355	578	4	0.28000000000000008	0.28000000000000008	NUM
american_scientific_journal-4355	578	5	0.30000000000000032	0.30000000000000032	NUM
american_scientific_journal-4355	578	6	c.unst.12h	c.unst.12h	PROPN
american_scientific_journal-4355	578	7	0.1	0.1	NUM
american_scientific_journal-4355	578	8	0.5	0.5	NUM
american_scientific_journal-4355	578	9	1	1	NUM
american_scientific_journal-4355	578	10	5.0ng	5.0ng	NUM
american_scientific_journal-4355	578	11	/	/	SYM
american_scientific_journal-4355	578	12	ml	ml	PROPN
american_scientific_journal-4355	578	13	1	1	NUM
american_scientific_journal-4355	578	14	2.1	2.1	NUM
american_scientific_journal-4355	578	15	3.3	3.3	NUM
american_scientific_journal-4355	578	16	2.4	2.4	NUM
american_scientific_journal-4355	578	17	2.5	2.5	NUM
american_scientific_journal-4355	578	18	relative	relative	ADJ
american_scientific_journal-4355	578	19	betaglycan	betaglycan	ADJ
american_scientific_journal-4355	578	20	expression	expression	NOUN
american_scientific_journal-4355	578	21	.	.	PUNCT
american_scientific_journal-4355	579	1	0.13526435023494923	0.13526435023494923	NUM
american_scientific_journal-4355	579	2	1	1	NUM
american_scientific_journal-4355	579	3	9.3388079182251046e-2	9.3388079182251046e-2	NUM
american_scientific_journal-4355	579	4	0.95175798030453462	0.95175798030453462	NUM
american_scientific_journal-4355	579	5	0.18006048366528346	0.18006048366528346	NUM
american_scientific_journal-4355	579	6	1.3575449798800041	1.3575449798800041	NUM
american_scientific_journal-4355	579	7	0.29945858552471716	0.29945858552471716	NUM
american_scientific_journal-4355	579	8	1.1908568493649687	1.1908568493649687	NUM
american_scientific_journal-4355	579	9	0.14564835888004893	0.14564835888004893	NUM
american_scientific_journal-4355	579	10	1.8192367879965599	1.8192367879965599	NUM
american_scientific_journal-4355	579	11	c.at	c.at	PROPN
american_scientific_journal-4355	579	12	12	12	NUM
american_scientific_journal-4355	579	13	h.	h.	NOUN
american_scientific_journal-4355	579	14	0.5	0.5	NUM
american_scientific_journal-4355	579	15	1.0	1.0	NUM
american_scientific_journal-4355	579	16	5.0	5.0	NUM
american_scientific_journal-4355	579	17	10	10	NUM
american_scientific_journal-4355	579	18	ng	ng	PROPN
american_scientific_journal-4355	579	19	/	/	SYM
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american_scientific_journal-4355	579	22	22	22	NUM
american_scientific_journal-4355	579	23	49	49	NUM
american_scientific_journal-4355	579	24	image2.jpeg	image2.jpeg	NOUN
american_scientific_journal-4355	579	25	image3.emf	image3.emf	X
american_scientific_journal-4355	579	26	microsoft_powerpoint_slide1.sldx	microsoft_powerpoint_slide1.sldx	PROPN
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american_scientific_journal-4355	579	30	image7.jpeg	image7.jpeg	NOUN
american_scientific_journal-4355	579	31	image8.png	image8.png	PART
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american_scientific_journal-4355	579	33	image10.png	image10.png	VERB
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american_scientific_journal-4355	580	2	image17.png	image17.png	ADJ
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american_scientific_journal-4355	580	4	image1.png	image1.png	PRON
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american_scientific_journal-4355	580	6	/	/	SYM
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american_scientific_journal-4355	580	8	slide	slide	VERB
american_scientific_journal-4355	580	9	2	2	NUM
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american_scientific_journal-4355	580	11	c	c	NOUN
american_scientific_journal-4355	580	12	o	o	NOUN
american_scientific_journal-4355	581	1	p	p	X
american_scientific_journal-4355	581	2	y	y	NOUN
american_scientific_journal-4355	581	3	r	r	NOUN
american_scientific_journal-4355	582	1	i	i	PRON
american_scientific_journal-4355	582	2	g	g	PROPN
american_scientific_journal-4355	582	3	h	h	NOUN
american_scientific_journal-4355	582	4	t	t	NOUN
american_scientific_journal-4355	583	1	©	©	NOUN
american_scientific_journal-4355	583	2	2	2	NUM
american_scientific_journal-4355	583	3	0	0	NUM
american_scientific_journal-4355	583	4	0	0	NUM
american_scientific_journal-4355	583	5	7	7	NUM
american_scientific_journal-4355	583	6	a	a	DET
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american_scientific_journal-4355	583	8	e	e	NOUN
american_scientific_journal-4355	583	9	r	r	NOUN
american_scientific_journal-4355	584	1	i	i	NOUN
american_scientific_journal-4355	584	2	c	c	VERB
american_scientific_journal-4355	584	3	a	a	DET
american_scientific_journal-4355	584	4	n	n	NOUN
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american_scientific_journal-4355	587	2	o	o	X
american_scientific_journal-4355	588	1	g	g	NOUN
american_scientific_journal-4355	589	1	i	i	PRON
american_scientific_journal-4355	589	2	c	c	VERB
american_scientific_journal-4355	589	3	a	a	DET
american_scientific_journal-4355	589	4	l	l	NOUN
american_scientific_journal-4355	589	5	s	s	PART
american_scientific_journal-4355	590	1	o	o	NOUN
american_scientific_journal-4355	590	2	c	c	NOUN
american_scientific_journal-4355	591	1	i	i	NOUN
american_scientific_journal-4355	591	2	e	e	PROPN
american_scientific_journal-4355	591	3	t	t	PROPN
american_scientific_journal-4355	591	4	y	y	PROPN
american_scientific_journal-4355	591	5	j	j	PROPN
american_scientific_journal-4355	591	6	u	u	PROPN
american_scientific_journal-4355	591	7	a	a	DET
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american_scientific_journal-4355	591	9	e	e	NOUN
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american_scientific_journal-4355	591	11	,	,	PUNCT
american_scientific_journal-4355	591	12	p	p	X
american_scientific_journal-4355	591	13	.	.	PUNCT
american_scientific_journal-4355	592	1	e	e	PROPN
american_scientific_journal-4355	592	2	t	t	PROPN
american_scientific_journal-4355	592	3	a	a	DET
american_scientific_journal-4355	592	4	l	l	NOUN
american_scientific_journal-4355	592	5	.	.	PUNCT
american_scientific_journal-4355	593	1	a	a	DET
american_scientific_journal-4355	593	2	m	m	NOUN
american_scientific_journal-4355	593	3	j	j	NOUN
american_scientific_journal-4355	593	4	p	p	NOUN
american_scientific_journal-4355	593	5	h	h	NOUN
american_scientific_journal-4355	594	1	y	y	NOUN
american_scientific_journal-4355	594	2	s	s	VERB
american_scientific_journal-4355	595	1	i	i	PRON
american_scientific_journal-4355	596	1	o	o	NOUN
american_scientific_journal-4355	596	2	l	l	NOUN
american_scientific_journal-4355	596	3	r	r	NOUN
american_scientific_journal-4355	596	4	e	e	NOUN
american_scientific_journal-4355	596	5	n	n	CCONJ
american_scientific_journal-4355	596	6	a	a	DET
american_scientific_journal-4355	596	7	l	l	NOUN
american_scientific_journal-4355	597	1	p	p	NOUN
american_scientific_journal-4355	597	2	h	h	NOUN
american_scientific_journal-4355	597	3	y	y	NOUN
american_scientific_journal-4355	597	4	s	s	VERB
american_scientific_journal-4355	598	1	i	i	PRON
american_scientific_journal-4355	598	2	o	o	NOUN
american_scientific_journal-4355	598	3	l	l	NOUN
american_scientific_journal-4355	598	4	2	2	NUM
american_scientific_journal-4355	598	5	9	9	NUM
american_scientific_journal-4355	598	6	2	2	NUM
american_scientific_journal-4355	598	7	:	:	PUNCT
american_scientific_journal-4355	598	8	f	f	NOUN
american_scientific_journal-4355	598	9	3	3	NUM
american_scientific_journal-4355	598	10	2	2	NUM
american_scientific_journal-4355	598	11	1	1	NUM
american_scientific_journal-4355	598	12	f	f	NOUN
american_scientific_journal-4355	598	13	3	3	NUM
american_scientific_journal-4355	598	14	2	2	NUM
american_scientific_journal-4355	598	15	9	9	NUM
american_scientific_journal-4355	598	16	2	2	NUM
american_scientific_journal-4355	598	17	0	0	NUM
american_scientific_journal-4355	598	18	0	0	NUM
american_scientific_journal-4355	598	19	7	7	NUM
american_scientific_journal-4355	598	20	;	;	PUNCT
american_scientific_journal-4355	599	1	d	d	X
american_scientific_journal-4355	599	2	o	o	X
american_scientific_journal-4355	600	1	i	i	PRON
american_scientific_journal-4355	600	2	:	:	PUNCT
american_scientific_journal-4355	600	3	1	1	NUM
american_scientific_journal-4355	600	4	0	0	NUM
american_scientific_journal-4355	600	5	.	.	PUNCT
american_scientific_journal-4355	601	1	1	1	NUM
american_scientific_journal-4355	601	2	1	1	NUM
american_scientific_journal-4355	601	3	5	5	NUM
american_scientific_journal-4355	601	4	2	2	NUM
american_scientific_journal-4355	601	5	/	/	SYM
american_scientific_journal-4355	601	6	a	a	DET
american_scientific_journal-4355	601	7	j	j	NOUN
american_scientific_journal-4355	601	8	p	p	NOUN
american_scientific_journal-4355	601	9	r	r	NOUN
american_scientific_journal-4355	601	10	e	e	NOUN
american_scientific_journal-4355	601	11	n	n	NOUN
american_scientific_journal-4355	601	12	a	a	DET
american_scientific_journal-4355	601	13	l	l	NOUN
american_scientific_journal-4355	601	14	.	.	PUNCT
american_scientific_journal-4355	602	1	0	0	NUM
american_scientific_journal-4355	602	2	0	0	NUM
american_scientific_journal-4355	602	3	2	2	NUM
american_scientific_journal-4355	602	4	6	6	NUM
american_scientific_journal-4355	602	5	4	4	NUM
american_scientific_journal-4355	602	6	.	.	PUNCT
american_scientific_journal-4355	603	1	2	2	NUM
american_scientific_journal-4355	603	2	0	0	NUM
american_scientific_journal-4355	603	3	0	0	NUM
american_scientific_journal-4355	603	4	6	6	NUM
american_scientific_journal-4355	603	5	b	b	PROPN
american_scientific_journal-4355	603	6	e	e	ADP
american_scientific_journal-4355	603	7	t	t	PROPN
american_scientific_journal-4355	603	8	a	a	DET
american_scientific_journal-4355	603	9	g	g	PROPN
american_scientific_journal-4355	603	10	l	l	NOUN
american_scientific_journal-4355	603	11	y	y	PROPN
american_scientific_journal-4355	603	12	c	c	PROPN
american_scientific_journal-4355	603	13	a	a	DET
american_scientific_journal-4355	603	14	n	n	PROPN
american_scientific_journal-4355	603	15	(	(	PUNCT
american_scientific_journal-4355	603	16	b	b	NOUN
american_scientific_journal-4355	603	17	g	g	NOUN
american_scientific_journal-4355	603	18	)	)	PUNCT
american_scientific_journal-4355	604	1	d	d	X
american_scientific_journal-4355	604	2	u	u	NOUN
american_scientific_journal-4355	604	3	a	a	DET
american_scientific_journal-4355	604	4	l	l	NOUN
american_scientific_journal-4355	604	5	m	m	NOUN
american_scientific_journal-4355	604	6	o	o	X
american_scientific_journal-4355	604	7	d	d	X
american_scientific_journal-4355	604	8	u	u	X
american_scientific_journal-4355	604	9	l	l	NOUN
american_scientific_journal-4355	604	10	a	a	NOUN
american_scientific_journal-4355	604	11	t	t	NOUN
american_scientific_journal-4355	605	1	i	i	PRON
american_scientific_journal-4355	605	2	o	o	VERB
american_scientific_journal-4355	606	1	n	n	X
american_scientific_journal-4355	607	1	o	o	X
american_scientific_journal-4355	607	2	f	f	NOUN
american_scientific_journal-4355	607	3	t	t	NOUN
american_scientific_journal-4355	607	4	g	g	PROPN
american_scientific_journal-4355	607	5	f	f	PROPN
american_scientific_journal-4355	607	6	b	b	PROPN
american_scientific_journal-4355	607	7	e	e	PROPN
american_scientific_journal-4355	607	8	t	t	PROPN
american_scientific_journal-4355	607	9	a	a	PRON
american_scientific_journal-4355	607	10	a	a	PRON
american_scientific_journal-4355	607	11	c	c	NOUN
american_scientific_journal-4355	607	12	t	t	NOUN
american_scientific_journal-4355	608	1	i	i	PRON
american_scientific_journal-4355	609	1	v	v	INTJ
american_scientific_journal-4355	610	1	i	i	PRON
american_scientific_journal-4355	610	2	t	t	NOUN
american_scientific_journal-4355	611	1	i	i	PRON
american_scientific_journal-4355	611	2	e	e	PROPN
american_scientific_journal-4355	611	3	s	s	PROPN
american_scientific_journal-4355	611	4	/docprops	/docprop	NOUN
american_scientific_journal-4355	611	5	/	/	SYM
american_scientific_journal-4355	612	1	thumbnail.jpeg	thumbnail.jpeg	PRON
american_scientific_journal-4355	612	2	slide	slide	VERB
american_scientific_journal-4355	612	3	1	1	NUM
american_scientific_journal-4355	612	4	copyright	copyright	NOUN
american_scientific_journal-4355	612	5	©	©	PROPN
american_scientific_journal-4355	612	6	2007	2007	NUM
american_scientific_journal-4355	612	7	american	american	ADJ
american_scientific_journal-4355	612	8	physiological	physiological	ADJ
american_scientific_journal-4355	612	9	society	society	NOUN
american_scientific_journal-4355	612	10	juarez	juarez	PROPN
american_scientific_journal-4355	612	11	,	,	PUNCT
american_scientific_journal-4355	612	12	p.	p.	NOUN
american_scientific_journal-4355	612	13	et	et	NOUN
american_scientific_journal-4355	613	1	al	al	PROPN
american_scientific_journal-4355	613	2	.	.	PROPN
american_scientific_journal-4355	613	3	am	be	AUX
american_scientific_journal-4355	613	4	j	j	PROPN
american_scientific_journal-4355	613	5	physiol	physiol	PROPN
american_scientific_journal-4355	613	6	renal	renal	PROPN
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american_scientific_journal-4355	613	8	292	292	NUM
american_scientific_journal-4355	613	9	:	:	PUNCT
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american_scientific_journal-4355	613	11	-	-	SYM
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american_scientific_journal-4355	613	13	2007	2007	NUM
american_scientific_journal-4355	613	14	;	;	PUNCT
american_scientific_journal-4355	613	15	doi:10.1152	doi:10.1152	NOUN
american_scientific_journal-4355	613	16	/	/	SYM
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american_scientific_journal-4355	613	19	(	(	PUNCT
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american_scientific_journal-4355	613	21	)	)	PUNCT
american_scientific_journal-4355	613	22	dual	dual	ADJ
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american_scientific_journal-4355	613	26	-	-	PUNCT
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american_scientific_journal-4355	613	29	image1.png	image1.png	PUNCT
american_scientific_journal-4355	614	1	image2.jpeg	image2.jpeg	NOUN
american_scientific_journal-4355	614	2	betaglycan≈300bpwithnostimulus123	betaglycan≈300bpwithnostimulus123	NOUN
american_scientific_journal-4355	614	3	b	b	PROPN
american_scientific_journal-4355	614	4	p	p	NOUN
american_scientific_journal-4355	614	5	dna	dna	NOUN
american_scientific_journal-4355	614	6	ladder	ladder	NOUN
american_scientific_journal-4355	614	7	10m3h6h12h24hc3	10m3h6h12h24hc3	NUM
american_scientific_journal-4355	614	8	h	h	NOUN
american_scientific_journal-4355	614	9	6	6	NUM
american_scientific_journal-4355	614	10	h	h	NOUN
american_scientific_journal-4355	614	11	12h	12h	NUM
american_scientific_journal-4355	614	12	24h	24h	X
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american_scientific_journal-4355	614	14	3h	3h	NUM
american_scientific_journal-4355	614	15	6	6	NUM
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american_scientific_journal-4355	614	18	24h	24h	X
american_scientific_journal-4355	614	19	c	c	X
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american_scientific_journal-4355	614	23	il-6	il-6	NOUN
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american_scientific_journal-4355	614	25	-	-	PUNCT
american_scientific_journal-4355	614	26	actinbands≈204	actinbands≈204	PROPN
american_scientific_journal-4355	614	27	bpbetaglycan≈300bpwithnostimulus123	bpbetaglycan≈300bpwithnostimulus123	PROPN
american_scientific_journal-4355	614	28	b	b	NOUN
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american_scientific_journal-4355	614	32	10m3h6h12h24hc3	10m3h6h12h24hc3	NUM
american_scientific_journal-4355	614	33	h	h	NOUN
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american_scientific_journal-4355	614	39	3h	3h	NUM
american_scientific_journal-4355	614	40	6	6	NUM
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american_scientific_journal-4355	614	43	24h	24h	X
american_scientific_journal-4355	614	44	c	c	X
american_scientific_journal-4355	614	45	betaglycan≈300	betaglycan≈300	NUM
american_scientific_journal-4355	614	46	bp	bp	PROPN
american_scientific_journal-4355	614	47	il-1	il-1	X
american_scientific_journal-4355	614	48	il-6	il-6	NOUN
american_scientific_journal-4355	614	49	beta	beta	NOUN
american_scientific_journal-4355	614	50	-	-	PUNCT
american_scientific_journal-4355	614	51	actinbands≈204	actinbands≈204	PROPN
american_scientific_journal-4355	614	52	bpbetaglycan≈300bpwithnostimulus123	bpbetaglycan≈300bpwithnostimulus123	PROPN
american_scientific_journal-4355	614	53	b	b	NOUN
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american_scientific_journal-4355	614	56	ladder	ladder	NOUN
american_scientific_journal-4355	614	57	10m3h6h12h24hc3	10m3h6h12h24hc3	NUM
american_scientific_journal-4355	614	58	h	h	NOUN
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american_scientific_journal-4355	614	68	24h	24h	X
american_scientific_journal-4355	614	69	c	c	X
american_scientific_journal-4355	614	70	betaglycan≈300	betaglycan≈300	NUM
american_scientific_journal-4355	614	71	bp	bp	PROPN
american_scientific_journal-4355	614	72	il-1	il-1	X
american_scientific_journal-4355	614	73	il-6	il-6	NOUN
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american_scientific_journal-4355	614	75	-	-	PUNCT
american_scientific_journal-4355	614	76	actinbands≈204	actinbands≈204	PROPN
american_scientific_journal-4355	614	77	bpbetaglycan≈300bpwithnostimulus123	bpbetaglycan≈300bpwithnostimulus123	PROPN
american_scientific_journal-4355	614	78	b	b	NOUN
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american_scientific_journal-4355	614	83	h	h	NOUN
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american_scientific_journal-4355	614	85	h	h	NOUN
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american_scientific_journal-4355	614	89	3h	3h	NUM
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american_scientific_journal-4355	614	93	24h	24h	X
american_scientific_journal-4355	614	94	c	c	X
american_scientific_journal-4355	614	95	betaglycan≈300	betaglycan≈300	NUM
american_scientific_journal-4355	614	96	bp	bp	PROPN
american_scientific_journal-4355	614	97	il-1	il-1	X
american_scientific_journal-4355	614	98	il-6	il-6	NOUN
american_scientific_journal-4355	614	99	beta	beta	NOUN
american_scientific_journal-4355	614	100	-	-	PUNCT
american_scientific_journal-4355	614	101	actinbands≈204	actinbands≈204	NOUN
american_scientific_journal-4355	614	102	bp	bp	NOUN
american_scientific_journal-4355	614	103	il-1il-6	il-1il-6	NOUN
american_scientific_journal-4355	614	104	00.20.40.60.811.21.46h12h24h48h72hrelative	00.20.40.60.811.21.46h12h24h48h72hrelative	ADJ
american_scientific_journal-4355	614	105	expression	expression	NOUN
american_scientific_journal-4355	614	106	of	of	ADP
american_scientific_journal-4355	614	107	betaglycanseries1series2	betaglycanseries1series2	NOUN
american_scientific_journal-4355	614	108	scramblebetaglycanknockdown	scramblebetaglycanknockdown	ADJ
american_scientific_journal-4355	614	109	*	*	NOUN
american_scientific_journal-4355	614	110	*	*	PUNCT
american_scientific_journal-4355	614	111	*	*	PUNCT
american_scientific_journal-4355	614	112	*	*	PUNCT
american_scientific_journal-4355	614	113	*	*	PUNCT
american_scientific_journal-4355	614	114	*	*	PUNCT
american_scientific_journal-4355	614	115	*	*	PUNCT