id	sid	tid	token	lemma	pos
american_scientific_journal-7186	1	1	313	313	NUM
american_scientific_journal-7186	1	2	american	american	ADJ
american_scientific_journal-7186	1	3	academic	academic	ADJ
american_scientific_journal-7186	1	4	scientific	scientific	ADJ
american_scientific_journal-7186	1	5	research	research	NOUN
american_scientific_journal-7186	1	6	journal	journal	NOUN
american_scientific_journal-7186	1	7	for	for	ADP
american_scientific_journal-7186	1	8	engineering	engineering	NOUN
american_scientific_journal-7186	1	9	,	,	PUNCT
american_scientific_journal-7186	1	10	technology	technology	NOUN
american_scientific_journal-7186	1	11	,	,	PUNCT
american_scientific_journal-7186	1	12	and	and	CCONJ
american_scientific_journal-7186	1	13	sciences	sciences	PROPN
american_scientific_journal-7186	1	14	issn	issn	PROPN
american_scientific_journal-7186	1	15	(	(	PUNCT
american_scientific_journal-7186	1	16	print	print	NOUN
american_scientific_journal-7186	1	17	)	)	PUNCT
american_scientific_journal-7186	1	18	2313	2313	NUM
american_scientific_journal-7186	1	19	-	-	SYM
american_scientific_journal-7186	1	20	4410	4410	NUM
american_scientific_journal-7186	1	21	,	,	PUNCT
american_scientific_journal-7186	1	22	issn	issn	PROPN
american_scientific_journal-7186	1	23	(	(	PUNCT
american_scientific_journal-7186	1	24	online	online	ADJ
american_scientific_journal-7186	1	25	)	)	PUNCT
american_scientific_journal-7186	1	26	2313	2313	NUM
american_scientific_journal-7186	1	27	-	-	SYM
american_scientific_journal-7186	1	28	4402	4402	NUM
american_scientific_journal-7186	1	29	http://asrjetsjournal.org/	http://asrjetsjournal.org/	NOUN
american_scientific_journal-7186	1	30	the	the	DET
american_scientific_journal-7186	1	31	working	work	VERB
american_scientific_journal-7186	1	32	mechanism	mechanism	NOUN
american_scientific_journal-7186	1	33	of	of	ADP
american_scientific_journal-7186	1	34	crispr	crispr	ADJ
american_scientific_journal-7186	1	35	/	/	SYM
american_scientific_journal-7186	1	36	cas9	cas9	NOUN
american_scientific_journal-7186	1	37	genome	genome	NOUN
american_scientific_journal-7186	1	38	editing	editing	NOUN
american_scientific_journal-7186	1	39	in	in	ADP
american_scientific_journal-7186	1	40	filamentous	filamentous	ADJ
american_scientific_journal-7186	1	41	fungi	fungus	NOUN
american_scientific_journal-7186	1	42	and	and	CCONJ
american_scientific_journal-7186	1	43	its	its	PRON
american_scientific_journal-7186	1	44	industrial	industrial	ADJ
american_scientific_journal-7186	1	45	applications	application	NOUN
american_scientific_journal-7186	1	46	muhammad	muhammad	PROPN
american_scientific_journal-7186	1	47	furqan	furqan	PROPN
american_scientific_journal-7186	1	48	arshad	arshad	PROPN
american_scientific_journal-7186	1	49	*	*	PUNCT
american_scientific_journal-7186	1	50	d-1/10	d-1/10	PROPN
american_scientific_journal-7186	1	51	east	east	PROPN
american_scientific_journal-7186	1	52	park	park	PROPN
american_scientific_journal-7186	1	53	,	,	PUNCT
american_scientific_journal-7186	1	54	wah	wah	PROPN
american_scientific_journal-7186	1	55	cantt	cantt	PROPN
american_scientific_journal-7186	1	56	email	email	NOUN
american_scientific_journal-7186	1	57	:	:	PUNCT
american_scientific_journal-7186	1	58	mfurqanarshad@outlook.com	mfurqanarshad@outlook.com	X
american_scientific_journal-7186	1	59	abstract	abstract	ADJ
american_scientific_journal-7186	1	60	understanding	understanding	NOUN
american_scientific_journal-7186	1	61	of	of	ADP
american_scientific_journal-7186	1	62	regulation	regulation	NOUN
american_scientific_journal-7186	1	63	of	of	ADP
american_scientific_journal-7186	1	64	gene	gene	NOUN
american_scientific_journal-7186	1	65	and	and	CCONJ
american_scientific_journal-7186	1	66	its	its	PRON
american_scientific_journal-7186	1	67	functions	function	NOUN
american_scientific_journal-7186	1	68	sequence	sequence	NOUN
american_scientific_journal-7186	1	69	which	which	PRON
american_scientific_journal-7186	1	70	is	be	AUX
american_scientific_journal-7186	1	71	coding	code	VERB
american_scientific_journal-7186	1	72	the	the	DET
american_scientific_journal-7186	1	73	gene	gene	NOUN
american_scientific_journal-7186	1	74	and	and	CCONJ
american_scientific_journal-7186	1	75	genome	genome	NOUN
american_scientific_journal-7186	1	76	manipulation	manipulation	NOUN
american_scientific_journal-7186	1	77	are	be	AUX
american_scientific_journal-7186	1	78	very	very	ADV
american_scientific_journal-7186	1	79	crucial	crucial	ADJ
american_scientific_journal-7186	1	80	.	.	PUNCT
american_scientific_journal-7186	2	1	for	for	ADP
american_scientific_journal-7186	2	2	this	this	DET
american_scientific_journal-7186	2	3	understanding	understand	VERB
american_scientific_journal-7186	2	4	conventional	conventional	ADJ
american_scientific_journal-7186	2	5	methods	method	NOUN
american_scientific_journal-7186	2	6	in	in	ADP
american_scientific_journal-7186	2	7	many	many	ADJ
american_scientific_journal-7186	2	8	filamentous	filamentous	ADJ
american_scientific_journal-7186	2	9	fungi	fungus	NOUN
american_scientific_journal-7186	2	10	are	be	AUX
american_scientific_journal-7186	2	11	either	either	CCONJ
american_scientific_journal-7186	2	12	non	non	ADJ
american_scientific_journal-7186	2	13	-	-	ADJ
american_scientific_journal-7186	2	14	functional	functional	ADJ
american_scientific_journal-7186	2	15	or	or	CCONJ
american_scientific_journal-7186	2	16	ineffective	ineffective	ADJ
american_scientific_journal-7186	2	17	.	.	PUNCT
american_scientific_journal-7186	3	1	filamentous	filamentous	ADJ
american_scientific_journal-7186	3	2	fungi	fungus	NOUN
american_scientific_journal-7186	3	3	plays	play	VERB
american_scientific_journal-7186	3	4	major	major	ADJ
american_scientific_journal-7186	3	5	role	role	NOUN
american_scientific_journal-7186	3	6	in	in	ADP
american_scientific_journal-7186	3	7	agriculture	agriculture	NOUN
american_scientific_journal-7186	3	8	,	,	PUNCT
american_scientific_journal-7186	3	9	industrial	industrial	ADJ
american_scientific_journal-7186	3	10	production	production	NOUN
american_scientific_journal-7186	3	11	and	and	CCONJ
american_scientific_journal-7186	3	12	in	in	ADP
american_scientific_journal-7186	3	13	medical	medical	ADJ
american_scientific_journal-7186	3	14	field	field	NOUN
american_scientific_journal-7186	3	15	.	.	PUNCT
american_scientific_journal-7186	4	1	a	a	DET
american_scientific_journal-7186	4	2	broad	broad	ADJ
american_scientific_journal-7186	4	3	applications	application	NOUN
american_scientific_journal-7186	4	4	and	and	CCONJ
american_scientific_journal-7186	4	5	fast	fast	ADJ
american_scientific_journal-7186	4	6	development	development	NOUN
american_scientific_journal-7186	4	7	of	of	ADP
american_scientific_journal-7186	4	8	system	system	NOUN
american_scientific_journal-7186	4	9	of	of	ADP
american_scientific_journal-7186	4	10	crispr	crispr	ADJ
american_scientific_journal-7186	4	11	/	/	SYM
american_scientific_journal-7186	4	12	cas9	cas9	NOUN
american_scientific_journal-7186	4	13	method	method	NOUN
american_scientific_journal-7186	4	14	has	have	AUX
american_scientific_journal-7186	4	15	given	give	VERB
american_scientific_journal-7186	4	16	the	the	DET
american_scientific_journal-7186	4	17	basic	basic	ADJ
american_scientific_journal-7186	4	18	outline	outline	NOUN
american_scientific_journal-7186	4	19	to	to	PART
american_scientific_journal-7186	4	20	comply	comply	VERB
american_scientific_journal-7186	4	21	this	this	DET
american_scientific_journal-7186	4	22	technology	technology	NOUN
american_scientific_journal-7186	4	23	of	of	ADP
american_scientific_journal-7186	4	24	editing	edit	VERB
american_scientific_journal-7186	4	25	of	of	ADP
american_scientific_journal-7186	4	26	gene	gene	NOUN
american_scientific_journal-7186	4	27	for	for	ADP
american_scientific_journal-7186	4	28	many	many	ADJ
american_scientific_journal-7186	4	29	filamentous	filamentous	ADJ
american_scientific_journal-7186	4	30	fungi	fungus	NOUN
american_scientific_journal-7186	4	31	.	.	PUNCT
american_scientific_journal-7186	5	1	in	in	ADP
american_scientific_journal-7186	5	2	this	this	DET
american_scientific_journal-7186	5	3	review	review	NOUN
american_scientific_journal-7186	5	4	,	,	PUNCT
american_scientific_journal-7186	5	5	by	by	ADP
american_scientific_journal-7186	5	6	focusing	focus	VERB
american_scientific_journal-7186	5	7	the	the	DET
american_scientific_journal-7186	5	8	applications	application	NOUN
american_scientific_journal-7186	5	9	of	of	ADP
american_scientific_journal-7186	5	10	crispr	crispr	NOUN
american_scientific_journal-7186	5	11	/	/	SYM
american_scientific_journal-7186	5	12	cas9	cas9	NOUN
american_scientific_journal-7186	5	13	in	in	ADP
american_scientific_journal-7186	5	14	research	research	NOUN
american_scientific_journal-7186	5	15	as	as	ADV
american_scientific_journal-7186	5	16	well	well	ADV
american_scientific_journal-7186	5	17	as	as	ADP
american_scientific_journal-7186	5	18	in	in	ADP
american_scientific_journal-7186	5	19	industries	industry	NOUN
american_scientific_journal-7186	5	20	we	we	PRON
american_scientific_journal-7186	5	21	give	give	VERB
american_scientific_journal-7186	5	22	the	the	DET
american_scientific_journal-7186	5	23	brief	brief	ADJ
american_scientific_journal-7186	5	24	introduction	introduction	NOUN
american_scientific_journal-7186	5	25	of	of	ADP
american_scientific_journal-7186	5	26	the	the	DET
american_scientific_journal-7186	5	27	crispr	crispr	ADJ
american_scientific_journal-7186	5	28	/	/	SYM
american_scientific_journal-7186	5	29	cas9	cas9	NOUN
american_scientific_journal-7186	5	30	system	system	NOUN
american_scientific_journal-7186	5	31	.	.	PUNCT
american_scientific_journal-7186	6	1	we	we	PRON
american_scientific_journal-7186	6	2	also	also	ADV
american_scientific_journal-7186	6	3	give	give	VERB
american_scientific_journal-7186	6	4	the	the	DET
american_scientific_journal-7186	6	5	brief	brief	ADJ
american_scientific_journal-7186	6	6	description	description	NOUN
american_scientific_journal-7186	6	7	of	of	ADP
american_scientific_journal-7186	6	8	overall	overall	ADJ
american_scientific_journal-7186	6	9	review	review	NOUN
american_scientific_journal-7186	6	10	of	of	ADP
american_scientific_journal-7186	6	11	editing	edit	VERB
american_scientific_journal-7186	6	12	of	of	ADP
american_scientific_journal-7186	6	13	genome	genome	NOUN
american_scientific_journal-7186	6	14	,	,	PUNCT
american_scientific_journal-7186	6	15	describe	describe	VERB
american_scientific_journal-7186	6	16	the	the	DET
american_scientific_journal-7186	6	17	construction	construction	NOUN
american_scientific_journal-7186	6	18	of	of	ADP
american_scientific_journal-7186	6	19	vector	vector	NOUN
american_scientific_journal-7186	6	20	,	,	PUNCT
american_scientific_journal-7186	6	21	off	off	ADP
american_scientific_journal-7186	6	22	targeted	target	VERB
american_scientific_journal-7186	6	23	effects	effect	NOUN
american_scientific_journal-7186	6	24	and	and	CCONJ
american_scientific_journal-7186	6	25	different	different	ADJ
american_scientific_journal-7186	6	26	methods	method	NOUN
american_scientific_journal-7186	6	27	of	of	ADP
american_scientific_journal-7186	6	28	transformation	transformation	NOUN
american_scientific_journal-7186	6	29	of	of	ADP
american_scientific_journal-7186	6	30	the	the	DET
american_scientific_journal-7186	6	31	plasmid	plasmid	ADJ
american_scientific_journal-7186	6	32	keywords	keyword	NOUN
american_scientific_journal-7186	6	33	:	:	PUNCT
american_scientific_journal-7186	7	1	crispr	crispr	ADJ
american_scientific_journal-7186	7	2	;	;	PUNCT
american_scientific_journal-7186	7	3	filamentous	filamentous	ADJ
american_scientific_journal-7186	7	4	fungi	fungus	NOUN
american_scientific_journal-7186	7	5	;	;	PUNCT
american_scientific_journal-7186	7	6	regulation	regulation	NOUN
american_scientific_journal-7186	7	7	of	of	ADP
american_scientific_journal-7186	7	8	gene	gene	NOUN
american_scientific_journal-7186	7	9	;	;	PUNCT
american_scientific_journal-7186	7	10	aspergillus	aspergillus	NOUN
american_scientific_journal-7186	7	11	oryzae	oryzae	NOUN
american_scientific_journal-7186	7	12	;	;	PUNCT
american_scientific_journal-7186	7	13	aspergillus	aspergillus	NOUN
american_scientific_journal-7186	7	14	niger	niger	NOUN
american_scientific_journal-7186	7	15	;	;	PUNCT
american_scientific_journal-7186	7	16	aspergillus	aspergillus	NOUN
american_scientific_journal-7186	7	17	nidulans	nidulan	NOUN
american_scientific_journal-7186	7	18	.	.	PUNCT
american_scientific_journal-7186	8	1	1	1	X
american_scientific_journal-7186	8	2	.	.	X
american_scientific_journal-7186	8	3	introduction	introduction	NOUN
american_scientific_journal-7186	8	4	aspergillus	aspergillus	NOUN
american_scientific_journal-7186	8	5	oryzae	oryzae	NOUN
american_scientific_journal-7186	8	6	,	,	PUNCT
american_scientific_journal-7186	8	7	aspergillus	aspergillus	NOUN
american_scientific_journal-7186	8	8	niger	niger	NOUN
american_scientific_journal-7186	8	9	,	,	PUNCT
american_scientific_journal-7186	8	10	aspergillus	aspergillus	NOUN
american_scientific_journal-7186	8	11	nidulans	nidulan	NOUN
american_scientific_journal-7186	8	12	and	and	CCONJ
american_scientific_journal-7186	8	13	rhopzus	rhopzus	PRON
american_scientific_journal-7186	8	14	oryzae	oryzae	NOUN
american_scientific_journal-7186	8	15	are	be	AUX
american_scientific_journal-7186	8	16	commonly	commonly	ADV
american_scientific_journal-7186	8	17	used	use	VERB
american_scientific_journal-7186	8	18	filamentous	filamentous	ADJ
american_scientific_journal-7186	8	19	fungi	fungus	NOUN
american_scientific_journal-7186	8	20	for	for	ADP
american_scientific_journal-7186	8	21	recombinase	recombinase	NOUN
american_scientific_journal-7186	8	22	and	and	CCONJ
american_scientific_journal-7186	8	23	enzymes	enzyme	NOUN
american_scientific_journal-7186	8	24	production	production	NOUN
american_scientific_journal-7186	8	25	.	.	PUNCT
american_scientific_journal-7186	9	1	filamentous	filamentous	ADJ
american_scientific_journal-7186	9	2	fungi	fungus	NOUN
american_scientific_journal-7186	9	3	commonly	commonly	ADV
american_scientific_journal-7186	9	4	used	use	VERB
american_scientific_journal-7186	9	5	for	for	ADP
american_scientific_journal-7186	9	6	manufacturing	manufacturing	NOUN
american_scientific_journal-7186	9	7	of	of	ADP
american_scientific_journal-7186	9	8	organic	organic	ADJ
american_scientific_journal-7186	9	9	acid	acid	NOUN
american_scientific_journal-7186	9	10	and	and	CCONJ
american_scientific_journal-7186	9	11	antibiotics	antibiotic	NOUN
american_scientific_journal-7186	9	12	and	and	CCONJ
american_scientific_journal-7186	9	13	heterologous	heterologous	ADJ
american_scientific_journal-7186	9	14	proteins	protein	NOUN
american_scientific_journal-7186	9	15	expression	expression	NOUN
american_scientific_journal-7186	9	16	[	[	X
american_scientific_journal-7186	9	17	1	1	NUM
american_scientific_journal-7186	9	18	]	]	PUNCT
american_scientific_journal-7186	9	19	.	.	PUNCT
american_scientific_journal-7186	10	1	a.	a.	NOUN
american_scientific_journal-7186	10	2	nidulans	nidulans	PROPN
american_scientific_journal-7186	10	3	and	and	CCONJ
american_scientific_journal-7186	10	4	n.	n.	PROPN
american_scientific_journal-7186	10	5	crassa	crassa	PROPN
american_scientific_journal-7186	10	6	are	be	AUX
american_scientific_journal-7186	10	7	filamentous	filamentous	ADJ
american_scientific_journal-7186	10	8	fungi	fungus	NOUN
american_scientific_journal-7186	10	9	which	which	PRON
american_scientific_journal-7186	10	10	are	be	AUX
american_scientific_journal-7186	10	11	commonly	commonly	ADV
american_scientific_journal-7186	10	12	used	use	VERB
american_scientific_journal-7186	10	13	for	for	ADP
american_scientific_journal-7186	10	14	basic	basic	ADJ
american_scientific_journal-7186	10	15	research	research	NOUN
american_scientific_journal-7186	10	16	as	as	ADP
american_scientific_journal-7186	10	17	a	a	DET
american_scientific_journal-7186	10	18	model	model	NOUN
american_scientific_journal-7186	10	19	organism	organism	NOUN
american_scientific_journal-7186	10	20	.	.	PUNCT
american_scientific_journal-7186	11	1	filamentous	filamentous	ADJ
american_scientific_journal-7186	11	2	fungi	fungus	NOUN
american_scientific_journal-7186	11	3	are	be	AUX
american_scientific_journal-7186	11	4	multicellular	multicellular	ADJ
american_scientific_journal-7186	11	5	microorganisms	microorganism	NOUN
american_scientific_journal-7186	11	6	.	.	PUNCT
american_scientific_journal-7186	12	1	the	the	DET
american_scientific_journal-7186	12	2	genome	genome	NOUN
american_scientific_journal-7186	12	3	of	of	ADP
american_scientific_journal-7186	12	4	filamentous	filamentous	ADJ
american_scientific_journal-7186	12	5	fungi	fungus	NOUN
american_scientific_journal-7186	12	6	is	be	AUX
american_scientific_journal-7186	12	7	more	more	ADV
american_scientific_journal-7186	12	8	complicated	complicated	ADJ
american_scientific_journal-7186	12	9	the	the	DET
american_scientific_journal-7186	12	10	bacteria	bacteria	NOUN
american_scientific_journal-7186	12	11	.	.	PUNCT
american_scientific_journal-7186	13	1	by	by	ADP
american_scientific_journal-7186	13	2	analysis	analysis	NOUN
american_scientific_journal-7186	13	3	of	of	ADP
american_scientific_journal-7186	13	4	rudimentary	rudimentary	ADJ
american_scientific_journal-7186	13	5	bioinformatics	bioinformatic	NOUN
american_scientific_journal-7186	13	6	,	,	PUNCT
american_scientific_journal-7186	13	7	eukaryotic	eukaryotic	ADJ
american_scientific_journal-7186	13	8	organisms	organism	NOUN
american_scientific_journal-7186	13	9	are	be	AUX
american_scientific_journal-7186	13	10	manipulate	manipulate	ADJ
american_scientific_journal-7186	13	11	by	by	ADP
american_scientific_journal-7186	13	12	simple	simple	ADJ
american_scientific_journal-7186	13	13	genome	genome	NOUN
american_scientific_journal-7186	13	14	of	of	ADP
american_scientific_journal-7186	13	15	bacteria	bacteria	NOUN
american_scientific_journal-7186	13	16	.	.	PUNCT
american_scientific_journal-7186	14	1	clustered	cluster	VERB
american_scientific_journal-7186	14	2	regularly	regularly	ADV
american_scientific_journal-7186	14	3	interspaced	interspace	VERB
american_scientific_journal-7186	14	4	short	short	ADJ
american_scientific_journal-7186	14	5	palindromic	palindromic	ADJ
american_scientific_journal-7186	14	6	repeats	repeat	NOUN
american_scientific_journal-7186	14	7	(	(	PUNCT
american_scientific_journal-7186	14	8	crispr	crispr	NOUN
american_scientific_journal-7186	14	9	)	)	PUNCT
american_scientific_journal-7186	14	10	are	be	AUX
american_scientific_journal-7186	14	11	same	same	ADJ
american_scientific_journal-7186	14	12	sequence	sequence	NOUN
american_scientific_journal-7186	14	13	of	of	ADP
american_scientific_journal-7186	14	14	bases	basis	NOUN
american_scientific_journal-7186	14	15	present	present	ADJ
american_scientific_journal-7186	14	16	in	in	ADP
american_scientific_journal-7186	14	17	the	the	DET
american_scientific_journal-7186	14	18	bacterial	bacterial	ADJ
american_scientific_journal-7186	14	19	phage	phage	NOUN
american_scientific_journal-7186	14	20	.	.	PUNCT
american_scientific_journal-7186	15	1	crispr	crispr	PROPN
american_scientific_journal-7186	15	2	is	be	AUX
american_scientific_journal-7186	15	3	essential	essential	ADJ
american_scientific_journal-7186	15	4	part	part	NOUN
american_scientific_journal-7186	15	5	of	of	ADP
american_scientific_journal-7186	15	6	immune	immune	ADJ
american_scientific_journal-7186	15	7	system	system	NOUN
american_scientific_journal-7186	15	8	of	of	ADP
american_scientific_journal-7186	15	9	bacteria	bacteria	NOUN
american_scientific_journal-7186	15	10	.	.	PUNCT
american_scientific_journal-7186	16	1	host	host	NOUN
american_scientific_journal-7186	16	2	bacteria	bacteria	NOUN
american_scientific_journal-7186	16	3	use	use	VERB
american_scientific_journal-7186	16	4	it	it	PRON
american_scientific_journal-7186	16	5	against	against	ADP
american_scientific_journal-7186	16	6	frequent	frequent	ADJ
american_scientific_journal-7186	16	7	infection	infection	NOUN
american_scientific_journal-7186	16	8	of	of	ADP
american_scientific_journal-7186	16	9	similar	similar	ADJ
american_scientific_journal-7186	16	10	phage	phage	NOUN
american_scientific_journal-7186	16	11	[	[	X
american_scientific_journal-7186	16	12	2	2	NUM
american_scientific_journal-7186	16	13	]	]	PUNCT
american_scientific_journal-7186	16	14	.	.	PUNCT
american_scientific_journal-7186	17	1	-----------------------------------------------------------------------	-----------------------------------------------------------------------	PUNCT
american_scientific_journal-7186	18	1	*	*	PUNCT
american_scientific_journal-7186	18	2	corresponding	correspond	VERB
american_scientific_journal-7186	18	3	author	author	NOUN
american_scientific_journal-7186	18	4	.	.	PUNCT
american_scientific_journal-7186	19	1	http://asrjetsjournal.org/	http://asrjetsjournal.org/	PROPN
american_scientific_journal-7186	19	2	american	american	PROPN
american_scientific_journal-7186	19	3	academic	academic	PROPN
american_scientific_journal-7186	19	4	scientific	scientific	ADJ
american_scientific_journal-7186	19	5	research	research	NOUN
american_scientific_journal-7186	19	6	journal	journal	NOUN
american_scientific_journal-7186	19	7	for	for	ADP
american_scientific_journal-7186	19	8	engineering	engineering	NOUN
american_scientific_journal-7186	19	9	,	,	PUNCT
american_scientific_journal-7186	19	10	technology	technology	NOUN
american_scientific_journal-7186	19	11	,	,	PUNCT
american_scientific_journal-7186	19	12	and	and	CCONJ
american_scientific_journal-7186	19	13	sciences(asrjets	sciences(asrjet	NOUN
american_scientific_journal-7186	19	14	)	)	PUNCT
american_scientific_journal-7186	20	1	(	(	PUNCT
american_scientific_journal-7186	20	2	2022)volume	2022)volume	NUM
american_scientific_journal-7186	20	3	85	85	NUM
american_scientific_journal-7186	20	4	,	,	PUNCT
american_scientific_journal-7186	20	5	no	no	DET
american_scientific_journal-7186	20	6	1	1	NUM
american_scientific_journal-7186	20	7	,	,	PUNCT
american_scientific_journal-7186	20	8	pp	pp	ADV
american_scientific_journal-7186	20	9	313	313	NUM
american_scientific_journal-7186	20	10	-	-	SYM
american_scientific_journal-7186	20	11	318	318	NUM
american_scientific_journal-7186	20	12	314	314	NUM
american_scientific_journal-7186	20	13	there	there	PRON
american_scientific_journal-7186	20	14	are	be	VERB
american_scientific_journal-7186	20	15	two	two	NUM
american_scientific_journal-7186	20	16	major	major	ADJ
american_scientific_journal-7186	20	17	classes	class	NOUN
american_scientific_journal-7186	20	18	of	of	ADP
american_scientific_journal-7186	20	19	crispr	crispr	NOUN
american_scientific_journal-7186	20	20	.	.	PUNCT
american_scientific_journal-7186	21	1	it	it	PRON
american_scientific_journal-7186	21	2	can	can	AUX
american_scientific_journal-7186	21	3	be	be	AUX
american_scientific_journal-7186	21	4	more	more	ADV
american_scientific_journal-7186	21	5	divided	divide	VERB
american_scientific_journal-7186	21	6	into	into	ADP
american_scientific_journal-7186	21	7	6	6	NUM
american_scientific_journal-7186	21	8	types	type	NOUN
american_scientific_journal-7186	21	9	and	and	CCONJ
american_scientific_journal-7186	21	10	19	19	NUM
american_scientific_journal-7186	21	11	subtypes	subtype	NOUN
american_scientific_journal-7186	21	12	.	.	PUNCT
american_scientific_journal-7186	22	1	type	type	NOUN
american_scientific_journal-7186	22	2	2	2	NUM
american_scientific_journal-7186	22	3	crispr	crispr	ADJ
american_scientific_journal-7186	22	4	case9	case9	NOUN
american_scientific_journal-7186	22	5	are	be	AUX
american_scientific_journal-7186	22	6	commonly	commonly	ADV
american_scientific_journal-7186	22	7	used	use	VERB
american_scientific_journal-7186	22	8	system	system	NOUN
american_scientific_journal-7186	22	9	which	which	PRON
american_scientific_journal-7186	22	10	include	include	VERB
american_scientific_journal-7186	22	11	trans	tran	NOUN
american_scientific_journal-7186	22	12	activating	activate	VERB
american_scientific_journal-7186	22	13	crrna	crrna	NOUN
american_scientific_journal-7186	22	14	(	(	PUNCT
american_scientific_journal-7186	22	15	tracr	tracr	PROPN
american_scientific_journal-7186	22	16	rna	rna	PROPN
american_scientific_journal-7186	22	17	)	)	PUNCT
american_scientific_journal-7186	22	18	,	,	PUNCT
american_scientific_journal-7186	22	19	rnase3	rnase3	PROPN
american_scientific_journal-7186	22	20	,	,	PUNCT
american_scientific_journal-7186	22	21	and	and	CCONJ
american_scientific_journal-7186	22	22	crispr	crispr	PROPN
american_scientific_journal-7186	22	23	associated	associate	VERB
american_scientific_journal-7186	22	24	rna	rna	PROPN
american_scientific_journal-7186	22	25	(	(	PUNCT
american_scientific_journal-7186	22	26	crrna	crrna	PROPN
american_scientific_journal-7186	22	27	)	)	PUNCT
american_scientific_journal-7186	22	28	.	.	PUNCT
american_scientific_journal-7186	23	1	crispr	crispr	ADJ
american_scientific_journal-7186	23	2	type	type	NOUN
american_scientific_journal-7186	23	3	2	2	NUM
american_scientific_journal-7186	23	4	are	be	AUX
american_scientific_journal-7186	23	5	more	more	ADV
american_scientific_journal-7186	23	6	commonly	commonly	ADV
american_scientific_journal-7186	23	7	used	use	VERB
american_scientific_journal-7186	23	8	and	and	CCONJ
american_scientific_journal-7186	23	9	simpler	simple	ADJ
american_scientific_journal-7186	23	10	than	than	ADP
american_scientific_journal-7186	23	11	other	other	ADJ
american_scientific_journal-7186	23	12	.	.	PUNCT
american_scientific_journal-7186	24	1	after	after	ADP
american_scientific_journal-7186	24	2	manufacturing	manufacturing	NOUN
american_scientific_journal-7186	24	3	of	of	ADP
american_scientific_journal-7186	24	4	system	system	NOUN
american_scientific_journal-7186	24	5	of	of	ADP
american_scientific_journal-7186	24	6	crispr	crispr	NOUN
american_scientific_journal-7186	24	7	/	/	SYM
american_scientific_journal-7186	24	8	cas9	cas9	NOUN
american_scientific_journal-7186	24	9	in	in	ADP
american_scientific_journal-7186	24	10	the	the	DET
american_scientific_journal-7186	24	11	cells	cell	NOUN
american_scientific_journal-7186	24	12	of	of	ADP
american_scientific_journal-7186	24	13	recipient	recipient	NOUN
american_scientific_journal-7186	24	14	,	,	PUNCT
american_scientific_journal-7186	24	15	cas9	cas9	NOUN
american_scientific_journal-7186	24	16	protein	protein	NOUN
american_scientific_journal-7186	24	17	are	be	AUX
american_scientific_journal-7186	24	18	attached	attach	VERB
american_scientific_journal-7186	24	19	with	with	ADP
american_scientific_journal-7186	24	20	the	the	DET
american_scientific_journal-7186	24	21	strand	strand	NOUN
american_scientific_journal-7186	24	22	complex	complex	NOUN
american_scientific_journal-7186	24	23	for	for	ADP
american_scientific_journal-7186	24	24	the	the	DET
american_scientific_journal-7186	24	25	formation	formation	NOUN
american_scientific_journal-7186	24	26	of	of	ADP
american_scientific_journal-7186	24	27	complex	complex	ADJ
american_scientific_journal-7186	24	28	tracrrna	tracrrna	NOUN
american_scientific_journal-7186	24	29	-	-	PUNCT
american_scientific_journal-7186	24	30	crrnapc	crrnapc	NOUN
american_scientific_journal-7186	24	31	-	-	PUNCT
american_scientific_journal-7186	24	32	cas9	cas9	NOUN
american_scientific_journal-7186	24	33	.	.	PUNCT
american_scientific_journal-7186	25	1	there	there	ADV
american_scientific_journal-7186	25	2	two	two	NUM
american_scientific_journal-7186	25	3	significant	significant	ADJ
american_scientific_journal-7186	25	4	domain	domain	NOUN
american_scientific_journal-7186	25	5	of	of	ADP
american_scientific_journal-7186	25	6	cas9	cas9	NOUN
american_scientific_journal-7186	25	7	protein	protein	NOUN
american_scientific_journal-7186	25	8	.	.	PUNCT
american_scientific_journal-7186	26	1	first	first	ADV
american_scientific_journal-7186	26	2	,	,	PUNCT
american_scientific_journal-7186	26	3	hnh	hnh	NOUN
american_scientific_journal-7186	26	4	domain	domain	NOUN
american_scientific_journal-7186	26	5	and	and	CCONJ
american_scientific_journal-7186	26	6	second	second	ADJ
american_scientific_journal-7186	26	7	ruvc	ruvc	NOUN
american_scientific_journal-7186	26	8	domain	domain	NOUN
american_scientific_journal-7186	26	9	.	.	PUNCT
american_scientific_journal-7186	27	1	after	after	ADP
american_scientific_journal-7186	27	2	binding	bind	VERB
american_scientific_journal-7186	27	3	to	to	ADP
american_scientific_journal-7186	27	4	the	the	DET
american_scientific_journal-7186	27	5	targeted	target	VERB
american_scientific_journal-7186	27	6	sequence	sequence	NOUN
american_scientific_journal-7186	27	7	,	,	PUNCT
american_scientific_journal-7186	27	8	under	under	ADP
american_scientific_journal-7186	27	9	the	the	DET
american_scientific_journal-7186	27	10	guidance	guidance	NOUN
american_scientific_journal-7186	27	11	of	of	ADP
american_scientific_journal-7186	27	12	sgrna	sgrna	NOUN
american_scientific_journal-7186	27	13	the	the	DET
american_scientific_journal-7186	27	14	domains	domain	NOUN
american_scientific_journal-7186	27	15	cleave	cleave	VERB
american_scientific_journal-7186	27	16	the	the	DET
american_scientific_journal-7186	27	17	double	double	ADJ
american_scientific_journal-7186	27	18	strands	strand	NOUN
american_scientific_journal-7186	27	19	of	of	ADP
american_scientific_journal-7186	27	20	the	the	DET
american_scientific_journal-7186	27	21	dna	dna	NOUN
american_scientific_journal-7186	27	22	.	.	PUNCT
american_scientific_journal-7186	28	1	the	the	DET
american_scientific_journal-7186	28	2	stands	stand	NOUN
american_scientific_journal-7186	28	3	of	of	ADP
american_scientific_journal-7186	28	4	dna	dna	PROPN
american_scientific_journal-7186	28	5	which	which	PRON
american_scientific_journal-7186	28	6	is	be	AUX
american_scientific_journal-7186	28	7	complementary	complementary	ADJ
american_scientific_journal-7186	28	8	to	to	ADP
american_scientific_journal-7186	28	9	the	the	DET
american_scientific_journal-7186	28	10	crrna	crrna	NOUN
american_scientific_journal-7186	28	11	are	be	AUX
american_scientific_journal-7186	28	12	cleaved	cleave	VERB
american_scientific_journal-7186	28	13	by	by	ADP
american_scientific_journal-7186	28	14	the	the	DET
american_scientific_journal-7186	28	15	nhn	nhn	PROPN
american_scientific_journal-7186	28	16	domain	domain	NOUN
american_scientific_journal-7186	28	17	.	.	PUNCT
american_scientific_journal-7186	29	1	the	the	DET
american_scientific_journal-7186	29	2	stand	stand	NOUN
american_scientific_journal-7186	29	3	which	which	PRON
american_scientific_journal-7186	29	4	is	be	AUX
american_scientific_journal-7186	29	5	not	not	PART
american_scientific_journal-7186	29	6	complementary	complementary	ADJ
american_scientific_journal-7186	29	7	to	to	ADP
american_scientific_journal-7186	29	8	the	the	DET
american_scientific_journal-7186	29	9	crrna	crrna	NOUN
american_scientific_journal-7186	29	10	are	be	AUX
american_scientific_journal-7186	29	11	cleaved	cleave	VERB
american_scientific_journal-7186	29	12	by	by	ADP
american_scientific_journal-7186	29	13	the	the	DET
american_scientific_journal-7186	29	14	ruvc	ruvc	PROPN
american_scientific_journal-7186	29	15	domain	domain	PROPN
american_scientific_journal-7186	29	16	[	[	X
american_scientific_journal-7186	29	17	3	3	NUM
american_scientific_journal-7186	29	18	]	]	PUNCT
american_scientific_journal-7186	29	19	.	.	PUNCT
american_scientific_journal-7186	30	1	after	after	SCONJ
american_scientific_journal-7186	30	2	the	the	DET
american_scientific_journal-7186	30	3	break	break	NOUN
american_scientific_journal-7186	30	4	of	of	ADP
american_scientific_journal-7186	30	5	double	double	ADJ
american_scientific_journal-7186	30	6	standard	standard	ADJ
american_scientific_journal-7186	30	7	dna	dna	PROPN
american_scientific_journal-7186	30	8	take	take	VERB
american_scientific_journal-7186	30	9	place	place	NOUN
american_scientific_journal-7186	30	10	dna	dna	NOUN
american_scientific_journal-7186	30	11	of	of	ADP
american_scientific_journal-7186	30	12	genome	genome	NOUN
american_scientific_journal-7186	30	13	start	start	VERB
american_scientific_journal-7186	30	14	self	self	NOUN
american_scientific_journal-7186	30	15	-	-	PUNCT
american_scientific_journal-7186	30	16	replication	replication	NOUN
american_scientific_journal-7186	30	17	.	.	PUNCT
american_scientific_journal-7186	31	1	as	as	ADP
american_scientific_journal-7186	31	2	result	result	NOUN
american_scientific_journal-7186	31	3	of	of	ADP
american_scientific_journal-7186	31	4	this	this	DET
american_scientific_journal-7186	31	5	replication	replication	NOUN
american_scientific_journal-7186	31	6	non	non	PRON
american_scientific_journal-7186	31	7	homologous	homologous	ADJ
american_scientific_journal-7186	31	8	ends	end	NOUN
american_scientific_journal-7186	31	9	of	of	ADP
american_scientific_journal-7186	31	10	dna	dna	PROPN
american_scientific_journal-7186	31	11	are	be	AUX
american_scientific_journal-7186	31	12	joint	joint	ADJ
american_scientific_journal-7186	31	13	together	together	ADV
american_scientific_journal-7186	31	14	and	and	CCONJ
american_scientific_journal-7186	31	15	will	will	AUX
american_scientific_journal-7186	31	16	produce	produce	VERB
american_scientific_journal-7186	31	17	the	the	DET
american_scientific_journal-7186	31	18	insertion	insertion	NOUN
american_scientific_journal-7186	31	19	,	,	PUNCT
american_scientific_journal-7186	31	20	bases	basis	NOUN
american_scientific_journal-7186	31	21	replacement	replacement	NOUN
american_scientific_journal-7186	31	22	and	and	CCONJ
american_scientific_journal-7186	31	23	random	random	ADJ
american_scientific_journal-7186	31	24	loss	loss	NOUN
american_scientific_journal-7186	31	25	.	.	PUNCT
american_scientific_journal-7186	32	1	by	by	ADP
american_scientific_journal-7186	32	2	the	the	DET
american_scientific_journal-7186	32	3	aid	aid	NOUN
american_scientific_journal-7186	32	4	of	of	ADP
american_scientific_journal-7186	32	5	exogenous	exogenous	ADJ
american_scientific_journal-7186	32	6	fragments	fragment	NOUN
american_scientific_journal-7186	32	7	,	,	PUNCT
american_scientific_journal-7186	32	8	the	the	DET
american_scientific_journal-7186	32	9	pathway	pathway	NOUN
american_scientific_journal-7186	32	10	of	of	ADP
american_scientific_journal-7186	32	11	hr	hr	NOUN
american_scientific_journal-7186	32	12	methods	method	NOUN
american_scientific_journal-7186	32	13	edit	edit	VERB
american_scientific_journal-7186	32	14	the	the	DET
american_scientific_journal-7186	32	15	gene	gene	NOUN
american_scientific_journal-7186	32	16	of	of	ADP
american_scientific_journal-7186	32	17	our	our	PRON
american_scientific_journal-7186	32	18	interest	interest	NOUN
american_scientific_journal-7186	32	19	.	.	PUNCT
american_scientific_journal-7186	33	1	1.1	1.1	NUM
american_scientific_journal-7186	33	2	.	.	X
american_scientific_journal-7186	33	3	working	work	VERB
american_scientific_journal-7186	33	4	mechanism	mechanism	NOUN
american_scientific_journal-7186	33	5	of	of	ADP
american_scientific_journal-7186	33	6	crispr	crispr	ADJ
american_scientific_journal-7186	33	7	case	case	NOUN
american_scientific_journal-7186	33	8	9	9	NUM
american_scientific_journal-7186	33	9	genome	genome	NOUN
american_scientific_journal-7186	33	10	editing	editing	NOUN
american_scientific_journal-7186	33	11	crispr	crispr	NOUN
american_scientific_journal-7186	33	12	is	be	AUX
american_scientific_journal-7186	33	13	a	a	DET
american_scientific_journal-7186	33	14	family	family	NOUN
american_scientific_journal-7186	33	15	of	of	ADP
american_scientific_journal-7186	33	16	repeats	repeat	NOUN
american_scientific_journal-7186	33	17	sequences	sequence	NOUN
american_scientific_journal-7186	33	18	of	of	ADP
american_scientific_journal-7186	33	19	dna	dna	NOUN
american_scientific_journal-7186	33	20	which	which	PRON
american_scientific_journal-7186	33	21	found	find	VERB
american_scientific_journal-7186	33	22	in	in	ADP
american_scientific_journal-7186	33	23	90	90	NUM
american_scientific_journal-7186	33	24	%	%	NOUN
american_scientific_journal-7186	33	25	of	of	ADP
american_scientific_journal-7186	33	26	genome	genome	NOUN
american_scientific_journal-7186	33	27	of	of	ADP
american_scientific_journal-7186	33	28	archaea	archaea	NOUN
american_scientific_journal-7186	33	29	and	and	CCONJ
american_scientific_journal-7186	33	30	40	40	NUM
american_scientific_journal-7186	33	31	%	%	NOUN
american_scientific_journal-7186	33	32	of	of	ADP
american_scientific_journal-7186	33	33	genome	genome	NOUN
american_scientific_journal-7186	33	34	of	of	ADP
american_scientific_journal-7186	33	35	bacteria	bacteria	NOUN
american_scientific_journal-7186	33	36	.	.	PUNCT
american_scientific_journal-7186	34	1	cas9	cas9	NOUN
american_scientific_journal-7186	34	2	is	be	AUX
american_scientific_journal-7186	34	3	a	a	DET
american_scientific_journal-7186	34	4	protein	protein	NOUN
american_scientific_journal-7186	34	5	(	(	PUNCT
american_scientific_journal-7186	34	6	dna	dna	NOUN
american_scientific_journal-7186	34	7	endonuclease	endonuclease	NOUN
american_scientific_journal-7186	34	8	)	)	PUNCT
american_scientific_journal-7186	34	9	combine	combine	VERB
american_scientific_journal-7186	34	10	with	with	ADP
american_scientific_journal-7186	34	11	tracrrna	tracrrna	NOUN
american_scientific_journal-7186	34	12	and	and	CCONJ
american_scientific_journal-7186	34	13	crrna	crrna	VERB
american_scientific_journal-7186	34	14	hybrid	hybrid	NOUN
american_scientific_journal-7186	34	15	and	and	CCONJ
american_scientific_journal-7186	34	16	form	form	VERB
american_scientific_journal-7186	34	17	a	a	DET
american_scientific_journal-7186	34	18	simple	simple	ADJ
american_scientific_journal-7186	34	19	immune	immune	ADJ
american_scientific_journal-7186	34	20	system	system	NOUN
american_scientific_journal-7186	34	21	of	of	ADP
american_scientific_journal-7186	34	22	bacteria	bacteria	NOUN
american_scientific_journal-7186	34	23	[	[	X
american_scientific_journal-7186	34	24	4	4	NUM
american_scientific_journal-7186	34	25	]	]	PUNCT
american_scientific_journal-7186	34	26	.	.	PUNCT
american_scientific_journal-7186	35	1	it	it	PRON
american_scientific_journal-7186	35	2	recognize	recognize	VERB
american_scientific_journal-7186	35	3	foreign	foreign	ADJ
american_scientific_journal-7186	35	4	dna	dna	NOUN
american_scientific_journal-7186	35	5	,	,	PUNCT
american_scientific_journal-7186	35	6	bind	bind	VERB
american_scientific_journal-7186	35	7	it	it	PRON
american_scientific_journal-7186	35	8	and	and	CCONJ
american_scientific_journal-7186	35	9	finally	finally	ADV
american_scientific_journal-7186	35	10	cut	cut	VERB
american_scientific_journal-7186	35	11	the	the	DET
american_scientific_journal-7186	35	12	foreign	foreign	ADJ
american_scientific_journal-7186	35	13	dna	dna	NOUN
american_scientific_journal-7186	35	14	.	.	PUNCT
american_scientific_journal-7186	36	1	protospacer	protospacer	NOUN
american_scientific_journal-7186	36	2	adjacent	adjacent	ADJ
american_scientific_journal-7186	36	3	motif	motif	NOUN
american_scientific_journal-7186	36	4	(	(	PUNCT
american_scientific_journal-7186	36	5	pam	pam	NOUN
american_scientific_journal-7186	36	6	)	)	PUNCT
american_scientific_journal-7186	36	7	which	which	PRON
american_scientific_journal-7186	36	8	is	be	AUX
american_scientific_journal-7186	36	9	present	present	ADJ
american_scientific_journal-7186	36	10	at	at	ADP
american_scientific_journal-7186	36	11	3	3	NUM
american_scientific_journal-7186	36	12	terminus	terminus	NOUN
american_scientific_journal-7186	36	13	of	of	ADP
american_scientific_journal-7186	36	14	targeted	target	VERB
american_scientific_journal-7186	36	15	dna	dna	NOUN
american_scientific_journal-7186	36	16	.	.	PUNCT
american_scientific_journal-7186	37	1	it	it	PRON
american_scientific_journal-7186	37	2	help	help	VERB
american_scientific_journal-7186	37	3	to	to	PART
american_scientific_journal-7186	37	4	recognize	recognize	VERB
american_scientific_journal-7186	37	5	the	the	DET
american_scientific_journal-7186	37	6	foreign	foreign	ADJ
american_scientific_journal-7186	37	7	dna	dna	NOUN
american_scientific_journal-7186	37	8	.	.	PUNCT
american_scientific_journal-7186	38	1	after	after	SCONJ
american_scientific_journal-7186	38	2	recognize	recognize	VERB
american_scientific_journal-7186	38	3	foreign	foreign	ADJ
american_scientific_journal-7186	38	4	dna	dna	PROPN
american_scientific_journal-7186	38	5	crisprcase9	crisprcase9	NOUN
american_scientific_journal-7186	38	6	will	will	AUX
american_scientific_journal-7186	38	7	produce	produce	VERB
american_scientific_journal-7186	38	8	a	a	DET
american_scientific_journal-7186	38	9	break	break	NOUN
american_scientific_journal-7186	38	10	in	in	ADP
american_scientific_journal-7186	38	11	double	double	ADJ
american_scientific_journal-7186	38	12	stands	stand	NOUN
american_scientific_journal-7186	38	13	of	of	ADP
american_scientific_journal-7186	38	14	dna	dna	NOUN
american_scientific_journal-7186	38	15	and	and	CCONJ
american_scientific_journal-7186	38	16	will	will	AUX
american_scientific_journal-7186	38	17	activate	activate	VERB
american_scientific_journal-7186	38	18	repair	repair	NOUN
american_scientific_journal-7186	38	19	process	process	NOUN
american_scientific_journal-7186	38	20	of	of	ADP
american_scientific_journal-7186	38	21	the	the	DET
american_scientific_journal-7186	38	22	host	host	NOUN
american_scientific_journal-7186	38	23	.	.	PUNCT
american_scientific_journal-7186	39	1	homologous	homologous	ADJ
american_scientific_journal-7186	39	2	recombination	recombination	NOUN
american_scientific_journal-7186	39	3	(	(	PUNCT
american_scientific_journal-7186	39	4	hr	hr	NOUN
american_scientific_journal-7186	39	5	)	)	PUNCT
american_scientific_journal-7186	39	6	and	and	CCONJ
american_scientific_journal-7186	39	7	non	non	PRON
american_scientific_journal-7186	39	8	homologous	homologous	ADJ
american_scientific_journal-7186	39	9	end	end	NOUN
american_scientific_journal-7186	39	10	joining	join	VERB
american_scientific_journal-7186	39	11	(	(	PUNCT
american_scientific_journal-7186	39	12	nhej	nhej	ADJ
american_scientific_journal-7186	39	13	)	)	PUNCT
american_scientific_journal-7186	39	14	are	be	AUX
american_scientific_journal-7186	39	15	two	two	NUM
american_scientific_journal-7186	39	16	cellular	cellular	ADJ
american_scientific_journal-7186	39	17	mechanisms	mechanism	NOUN
american_scientific_journal-7186	39	18	which	which	PRON
american_scientific_journal-7186	39	19	play	play	VERB
american_scientific_journal-7186	39	20	an	an	DET
american_scientific_journal-7186	39	21	important	important	ADJ
american_scientific_journal-7186	39	22	role	role	NOUN
american_scientific_journal-7186	39	23	in	in	ADP
american_scientific_journal-7186	39	24	manipulation	manipulation	NOUN
american_scientific_journal-7186	39	25	of	of	ADP
american_scientific_journal-7186	39	26	genome	genome	NOUN
american_scientific_journal-7186	39	27	and	and	CCONJ
american_scientific_journal-7186	39	28	genome	genome	NOUN
american_scientific_journal-7186	39	29	editing	editing	NOUN
american_scientific_journal-7186	39	30	in	in	ADP
american_scientific_journal-7186	39	31	precise	precise	ADJ
american_scientific_journal-7186	39	32	manner	manner	NOUN
american_scientific_journal-7186	39	33	.	.	PUNCT
american_scientific_journal-7186	40	1	nhej	nhej	PROPN
american_scientific_journal-7186	40	2	has	have	AUX
american_scientific_journal-7186	40	3	been	be	AUX
american_scientific_journal-7186	40	4	observed	observe	VERB
american_scientific_journal-7186	40	5	as	as	ADP
american_scientific_journal-7186	40	6	error	error	NOUN
american_scientific_journal-7186	40	7	prone	prone	ADJ
american_scientific_journal-7186	40	8	repair	repair	NOUN
american_scientific_journal-7186	40	9	mechanism	mechanism	NOUN
american_scientific_journal-7186	40	10	.	.	PUNCT
american_scientific_journal-7186	41	1	it	it	PRON
american_scientific_journal-7186	41	2	produce	produce	VERB
american_scientific_journal-7186	41	3	the	the	DET
american_scientific_journal-7186	41	4	short	short	ADJ
american_scientific_journal-7186	41	5	deletion	deletion	NOUN
american_scientific_journal-7186	41	6	or	or	CCONJ
american_scientific_journal-7186	41	7	insertions	insertion	NOUN
american_scientific_journal-7186	41	8	of	of	ADP
american_scientific_journal-7186	41	9	bases	basis	NOUN
american_scientific_journal-7186	41	10	in	in	ADP
american_scientific_journal-7186	41	11	adjacent	adjacent	ADJ
american_scientific_journal-7186	41	12	vicinity	vicinity	NOUN
american_scientific_journal-7186	41	13	of	of	ADP
american_scientific_journal-7186	41	14	double	double	ADJ
american_scientific_journal-7186	41	15	bond	bond	NOUN
american_scientific_journal-7186	41	16	.	.	PUNCT
american_scientific_journal-7186	42	1	if	if	SCONJ
american_scientific_journal-7186	42	2	in	in	ADP
american_scientific_journal-7186	42	3	coding	code	VERB
american_scientific_journal-7186	42	4	region	region	NOUN
american_scientific_journal-7186	42	5	of	of	ADP
american_scientific_journal-7186	42	6	genome	genome	NOUN
american_scientific_journal-7186	42	7	or	or	CCONJ
american_scientific_journal-7186	42	8	with	with	ADP
american_scientific_journal-7186	42	9	in	in	ADP
american_scientific_journal-7186	42	10	promoter	promoter	NOUN
american_scientific_journal-7186	42	11	a	a	DET
american_scientific_journal-7186	42	12	small	small	ADJ
american_scientific_journal-7186	42	13	deletion	deletion	NOUN
american_scientific_journal-7186	42	14	or	or	CCONJ
american_scientific_journal-7186	42	15	insertion	insertion	NOUN
american_scientific_journal-7186	42	16	is	be	AUX
american_scientific_journal-7186	42	17	present	present	ADJ
american_scientific_journal-7186	42	18	,	,	PUNCT
american_scientific_journal-7186	42	19	it	it	PRON
american_scientific_journal-7186	42	20	will	will	AUX
american_scientific_journal-7186	42	21	disturb	disturb	VERB
american_scientific_journal-7186	42	22	the	the	DET
american_scientific_journal-7186	42	23	working	working	NOUN
american_scientific_journal-7186	42	24	of	of	ADP
american_scientific_journal-7186	42	25	endogenous	endogenous	ADJ
american_scientific_journal-7186	42	26	gene	gene	NOUN
american_scientific_journal-7186	42	27	.	.	PUNCT
american_scientific_journal-7186	43	1	a	a	DET
american_scientific_journal-7186	43	2	double	double	ADJ
american_scientific_journal-7186	43	3	stranded	strand	VERB
american_scientific_journal-7186	43	4	pathway	pathway	NOUN
american_scientific_journal-7186	43	5	called	call	VERB
american_scientific_journal-7186	43	6	homology	homology	NOUN
american_scientific_journal-7186	43	7	repair	repair	NOUN
american_scientific_journal-7186	43	8	depend	depend	VERB
american_scientific_journal-7186	43	9	on	on	ADP
american_scientific_journal-7186	43	10	template	template	NOUN
american_scientific_journal-7186	43	11	dna	dna	NOUN
american_scientific_journal-7186	43	12	.	.	PUNCT
american_scientific_journal-7186	44	1	i	i	PRON
american_scientific_journal-7186	44	2	allow	allow	VERB
american_scientific_journal-7186	44	3	the	the	DET
american_scientific_journal-7186	44	4	foreign	foreign	ADJ
american_scientific_journal-7186	44	5	fragments	fragment	NOUN
american_scientific_journal-7186	44	6	of	of	ADP
american_scientific_journal-7186	44	7	dna	dna	NOUN
american_scientific_journal-7186	44	8	to	to	PART
american_scientific_journal-7186	44	9	assimilate	assimilate	VERB
american_scientific_journal-7186	44	10	into	into	ADP
american_scientific_journal-7186	44	11	genome	genome	NOUN
american_scientific_journal-7186	44	12	of	of	ADP
american_scientific_journal-7186	44	13	host	host	NOUN
american_scientific_journal-7186	44	14	.	.	PUNCT
american_scientific_journal-7186	45	1	homology	homology	NOUN
american_scientific_journal-7186	45	2	repair	repair	NOUN
american_scientific_journal-7186	45	3	only	only	ADV
american_scientific_journal-7186	45	4	take	take	VERB
american_scientific_journal-7186	45	5	place	place	NOUN
american_scientific_journal-7186	45	6	in	in	ADP
american_scientific_journal-7186	45	7	cells	cell	NOUN
american_scientific_journal-7186	45	8	which	which	PRON
american_scientific_journal-7186	45	9	are	be	AUX
american_scientific_journal-7186	45	10	dividing	divide	VERB
american_scientific_journal-7186	45	11	due	due	ADJ
american_scientific_journal-7186	45	12	to	to	ADP
american_scientific_journal-7186	45	13	which	which	PRON
american_scientific_journal-7186	45	14	this	this	DET
american_scientific_journal-7186	45	15	method	method	NOUN
american_scientific_journal-7186	45	16	has	have	VERB
american_scientific_journal-7186	45	17	a	a	DET
american_scientific_journal-7186	45	18	limited	limited	ADJ
american_scientific_journal-7186	45	19	applications	application	NOUN
american_scientific_journal-7186	45	20	[	[	X
american_scientific_journal-7186	45	21	5	5	NUM
american_scientific_journal-7186	45	22	]	]	PUNCT
american_scientific_journal-7186	45	23	.	.	PUNCT
american_scientific_journal-7186	46	1	1.2	1.2	NUM
american_scientific_journal-7186	46	2	.	.	PUNCT
american_scientific_journal-7186	46	3	cas9	cas9	NOUN
american_scientific_journal-7186	46	4	expression	expression	NOUN
american_scientific_journal-7186	46	5	the	the	DET
american_scientific_journal-7186	46	6	significant	significant	ADJ
american_scientific_journal-7186	46	7	constituent	constituent	NOUN
american_scientific_journal-7186	46	8	of	of	ADP
american_scientific_journal-7186	46	9	crispr/	crispr/	NUM
american_scientific_journal-7186	46	10	cas9	cas9	NOUN
american_scientific_journal-7186	46	11	is	be	AUX
american_scientific_journal-7186	46	12	cas9	cas9	NOUN
american_scientific_journal-7186	46	13	protein	protein	NOUN
american_scientific_journal-7186	46	14	.	.	PUNCT
american_scientific_journal-7186	47	1	it	it	PRON
american_scientific_journal-7186	47	2	contain	contain	VERB
american_scientific_journal-7186	47	3	about	about	ADV
american_scientific_journal-7186	47	4	1400	1400	NUM
american_scientific_journal-7186	47	5	amino	amino	NOUN
american_scientific_journal-7186	47	6	acids	acid	NOUN
american_scientific_journal-7186	47	7	and	and	CCONJ
american_scientific_journal-7186	47	8	has	have	VERB
american_scientific_journal-7186	47	9	endonuclease	endonuclease	NOUN
american_scientific_journal-7186	47	10	functions	function	NOUN
american_scientific_journal-7186	47	11	.	.	PUNCT
american_scientific_journal-7186	48	1	firstly	firstly	ADV
american_scientific_journal-7186	48	2	in	in	ADP
american_scientific_journal-7186	48	3	archaea	archaea	ADJ
american_scientific_journal-7186	48	4	and	and	CCONJ
american_scientific_journal-7186	48	5	bacteria	bacteria	NOUN
american_scientific_journal-7186	48	6	crispr/	crispr/	NUM
american_scientific_journal-7186	48	7	cas9	cas9	NOUN
american_scientific_journal-7186	48	8	was	be	AUX
american_scientific_journal-7186	48	9	discovered	discover	VERB
american_scientific_journal-7186	48	10	.	.	PUNCT
american_scientific_journal-7186	49	1	in	in	ADP
american_scientific_journal-7186	49	2	fungi	fungi	PROPN
american_scientific_journal-7186	49	3	,	,	PUNCT
american_scientific_journal-7186	49	4	when	when	SCONJ
american_scientific_journal-7186	49	5	system	system	NOUN
american_scientific_journal-7186	49	6	of	of	ADP
american_scientific_journal-7186	49	7	crispr/	crispr/	NUM
american_scientific_journal-7186	49	8	cas9	cas9	NOUN
american_scientific_journal-7186	49	9	is	be	AUX
american_scientific_journal-7186	49	10	used	use	VERB
american_scientific_journal-7186	49	11	at	at	ADP
american_scientific_journal-7186	49	12	both	both	DET
american_scientific_journal-7186	49	13	end	end	NOUN
american_scientific_journal-7186	49	14	of	of	ADP
american_scientific_journal-7186	49	15	the	the	DET
american_scientific_journal-7186	49	16	cas9	cas9	NOUN
american_scientific_journal-7186	49	17	gene	gene	NOUN
american_scientific_journal-7186	49	18	both	both	DET
american_scientific_journal-7186	49	19	signals	signal	NOUN
american_scientific_journal-7186	49	20	of	of	ADP
american_scientific_journal-7186	49	21	nuclear	nuclear	ADJ
american_scientific_journal-7186	49	22	localization	localization	NOUN
american_scientific_journal-7186	49	23	and	and	CCONJ
american_scientific_journal-7186	49	24	optimized	optimize	VERB
american_scientific_journal-7186	49	25	codons	codon	NOUN
american_scientific_journal-7186	49	26	are	be	AUX
american_scientific_journal-7186	49	27	added	add	VERB
american_scientific_journal-7186	49	28	[	[	X
american_scientific_journal-7186	49	29	6	6	NUM
american_scientific_journal-7186	49	30	]	]	PUNCT
american_scientific_journal-7186	49	31	.	.	PUNCT
american_scientific_journal-7186	50	1	promoter	promoter	NOUN
american_scientific_journal-7186	50	2	strength	strength	NOUN
american_scientific_journal-7186	50	3	in	in	ADP
american_scientific_journal-7186	50	4	driving	drive	VERB
american_scientific_journal-7186	50	5	the	the	DET
american_scientific_journal-7186	50	6	process	process	NOUN
american_scientific_journal-7186	50	7	of	of	ADP
american_scientific_journal-7186	50	8	transcription	transcription	NOUN
american_scientific_journal-7186	50	9	is	be	AUX
american_scientific_journal-7186	50	10	very	very	ADV
american_scientific_journal-7186	50	11	significant	significant	ADJ
american_scientific_journal-7186	50	12	factor	factor	NOUN
american_scientific_journal-7186	50	13	.	.	PUNCT
american_scientific_journal-7186	51	1	it	it	PRON
american_scientific_journal-7186	51	2	affect	affect	VERB
american_scientific_journal-7186	51	3	the	the	DET
american_scientific_journal-7186	51	4	ability	ability	NOUN
american_scientific_journal-7186	51	5	of	of	ADP
american_scientific_journal-7186	51	6	gene	gene	NOUN
american_scientific_journal-7186	51	7	expression	expression	NOUN
american_scientific_journal-7186	51	8	exogenously	exogenously	ADV
american_scientific_journal-7186	51	9	.	.	PUNCT
american_scientific_journal-7186	52	1	selection	selection	NOUN
american_scientific_journal-7186	52	2	of	of	ADP
american_scientific_journal-7186	52	3	the	the	DET
american_scientific_journal-7186	52	4	promoter	promoter	NOUN
american_scientific_journal-7186	52	5	has	have	VERB
american_scientific_journal-7186	52	6	a	a	DET
american_scientific_journal-7186	52	7	great	great	ADJ
american_scientific_journal-7186	52	8	importance	importance	NOUN
american_scientific_journal-7186	52	9	for	for	ADP
american_scientific_journal-7186	52	10	activity	activity	NOUN
american_scientific_journal-7186	52	11	of	of	ADP
american_scientific_journal-7186	52	12	crispr/	crispr/	NUM
american_scientific_journal-7186	52	13	cas9	cas9	NOUN
american_scientific_journal-7186	52	14	system	system	NOUN
american_scientific_journal-7186	52	15	.	.	PUNCT
american_scientific_journal-7186	53	1	in	in	ADP
american_scientific_journal-7186	53	2	filamentous	filamentous	ADJ
american_scientific_journal-7186	53	3	fungi	fungus	NOUN
american_scientific_journal-7186	53	4	,	,	PUNCT
american_scientific_journal-7186	53	5	the	the	DET
american_scientific_journal-7186	53	6	promoter	promoter	NOUN
american_scientific_journal-7186	53	7	use	use	NOUN
american_scientific_journal-7186	53	8	to	to	PART
american_scientific_journal-7186	53	9	drive	drive	VERB
american_scientific_journal-7186	53	10	level	level	NOUN
american_scientific_journal-7186	53	11	of	of	ADP
american_scientific_journal-7186	53	12	expression	expression	NOUN
american_scientific_journal-7186	53	13	of	of	ADP
american_scientific_journal-7186	53	14	cas9	cas9	NOUN
american_scientific_journal-7186	53	15	protein	protein	NOUN
american_scientific_journal-7186	53	16	are	be	AUX
american_scientific_journal-7186	53	17	constitutive	constitutive	ADJ
american_scientific_journal-7186	53	18	promoter	promoter	NOUN
american_scientific_journal-7186	53	19	.	.	PUNCT
american_scientific_journal-7186	54	1	the	the	DET
american_scientific_journal-7186	54	2	promoter	promoter	NOUN
american_scientific_journal-7186	54	3	use	use	NOUN
american_scientific_journal-7186	54	4	for	for	ADP
american_scientific_journal-7186	54	5	the	the	DET
american_scientific_journal-7186	54	6	expression	expression	NOUN
american_scientific_journal-7186	54	7	of	of	ADP
american_scientific_journal-7186	54	8	protein	protein	NOUN
american_scientific_journal-7186	54	9	are	be	AUX
american_scientific_journal-7186	54	10	comparatively	comparatively	ADV
american_scientific_journal-7186	54	11	stable	stable	ADJ
american_scientific_journal-7186	54	12	.	.	PUNCT
american_scientific_journal-7186	55	1	promoters	promoter	NOUN
american_scientific_journal-7186	55	2	in	in	ADP
american_scientific_journal-7186	55	3	a.nidulans	a.nidulan	NOUN
american_scientific_journal-7186	55	4	such	such	ADJ
american_scientific_journal-7186	55	5	as	as	ADP
american_scientific_journal-7186	55	6	gpda	gpda	NOUN
american_scientific_journal-7186	55	7	promoter	promoter	NOUN
american_scientific_journal-7186	55	8	(	(	PUNCT
american_scientific_journal-7186	55	9	g-3	g-3	NOUN
american_scientific_journal-7186	55	10	-	-	PUNCT
american_scientific_journal-7186	55	11	p	p	NOUN
american_scientific_journal-7186	55	12	dehydrogenase	dehydrogenase	NOUN
american_scientific_journal-7186	55	13	synthesis	synthesis	NOUN
american_scientific_journal-7186	55	14	gene	gene	NOUN
american_scientific_journal-7186	55	15	)	)	PUNCT
american_scientific_journal-7186	55	16	promoter	promoter	NOUN
american_scientific_journal-7186	55	17	trpc	trpc	NOUN
american_scientific_journal-7186	55	18	promoter	promoter	NOUN
american_scientific_journal-7186	55	19	(	(	PUNCT
american_scientific_journal-7186	55	20	tryptophan	tryptophan	NOUN
american_scientific_journal-7186	55	21	synthesis	synthesis	NOUN
american_scientific_journal-7186	55	22	gene	gene	NOUN
american_scientific_journal-7186	55	23	)	)	PUNCT
american_scientific_journal-7186	55	24	are	be	AUX
american_scientific_journal-7186	55	25	use	use	NOUN
american_scientific_journal-7186	55	26	in	in	ADP
american_scientific_journal-7186	55	27	filamentous	filamentous	ADJ
american_scientific_journal-7186	55	28	fungi	fungus	NOUN
american_scientific_journal-7186	55	29	[	[	X
american_scientific_journal-7186	55	30	7	7	NUM
american_scientific_journal-7186	55	31	]	]	PUNCT
american_scientific_journal-7186	55	32	.	.	PUNCT
american_scientific_journal-7186	56	1	some	some	DET
american_scientific_journal-7186	56	2	studied	study	VERB
american_scientific_journal-7186	56	3	reported	report	VERB
american_scientific_journal-7186	56	4	expression	expression	NOUN
american_scientific_journal-7186	56	5	of	of	ADP
american_scientific_journal-7186	56	6	foreign	foreign	ADJ
american_scientific_journal-7186	56	7	genes	gene	NOUN
american_scientific_journal-7186	56	8	of	of	ADP
american_scientific_journal-7186	56	9	cas9	cas9	NOUN
american_scientific_journal-7186	56	10	protein	protein	NOUN
american_scientific_journal-7186	56	11	has	have	VERB
american_scientific_journal-7186	56	12	negative	negative	ADJ
american_scientific_journal-7186	56	13	effect	effect	NOUN
american_scientific_journal-7186	56	14	on	on	ADP
american_scientific_journal-7186	56	15	recipient	recipient	NOUN
american_scientific_journal-7186	56	16	organisms	organism	NOUN
american_scientific_journal-7186	56	17	.	.	PUNCT
american_scientific_journal-7186	57	1	therefore	therefore	ADV
american_scientific_journal-7186	57	2	it	it	PRON
american_scientific_journal-7186	57	3	is	be	AUX
american_scientific_journal-7186	57	4	significant	significant	ADJ
american_scientific_journal-7186	57	5	to	to	PART
american_scientific_journal-7186	57	6	confirm	confirm	VERB
american_scientific_journal-7186	57	7	that	that	SCONJ
american_scientific_journal-7186	57	8	expression	expression	NOUN
american_scientific_journal-7186	57	9	of	of	ADP
american_scientific_journal-7186	57	10	cas9	cas9	NOUN
american_scientific_journal-7186	57	11	protein	protein	NOUN
american_scientific_journal-7186	57	12	has	have	VERB
american_scientific_journal-7186	57	13	american	american	ADJ
american_scientific_journal-7186	57	14	academic	academic	ADJ
american_scientific_journal-7186	57	15	scientific	scientific	ADJ
american_scientific_journal-7186	57	16	research	research	NOUN
american_scientific_journal-7186	57	17	journal	journal	NOUN
american_scientific_journal-7186	57	18	for	for	ADP
american_scientific_journal-7186	57	19	engineering	engineering	NOUN
american_scientific_journal-7186	57	20	,	,	PUNCT
american_scientific_journal-7186	57	21	technology	technology	NOUN
american_scientific_journal-7186	57	22	,	,	PUNCT
american_scientific_journal-7186	57	23	and	and	CCONJ
american_scientific_journal-7186	57	24	sciences(asrjets	sciences(asrjet	NOUN
american_scientific_journal-7186	57	25	)	)	PUNCT
american_scientific_journal-7186	57	26	(	(	PUNCT
american_scientific_journal-7186	57	27	2022)volume	2022)volume	NUM
american_scientific_journal-7186	57	28	85	85	NUM
american_scientific_journal-7186	57	29	,	,	PUNCT
american_scientific_journal-7186	57	30	no	no	DET
american_scientific_journal-7186	57	31	1	1	NUM
american_scientific_journal-7186	57	32	,	,	PUNCT
american_scientific_journal-7186	57	33	pp	pp	ADV
american_scientific_journal-7186	57	34	313	313	NUM
american_scientific_journal-7186	57	35	-	-	SYM
american_scientific_journal-7186	57	36	318	318	NUM
american_scientific_journal-7186	57	37	315	315	NUM
american_scientific_journal-7186	57	38	no	no	DET
american_scientific_journal-7186	57	39	negative	negative	ADJ
american_scientific_journal-7186	57	40	effect	effect	NOUN
american_scientific_journal-7186	57	41	by	by	ADP
american_scientific_journal-7186	57	42	testing	test	VERB
american_scientific_journal-7186	57	43	the	the	DET
american_scientific_journal-7186	57	44	growth	growth	NOUN
american_scientific_journal-7186	57	45	of	of	ADP
american_scientific_journal-7186	57	46	expression	expression	NOUN
american_scientific_journal-7186	57	47	strain	strain	NOUN
american_scientific_journal-7186	57	48	,	,	PUNCT
american_scientific_journal-7186	57	49	resistance	resistance	NOUN
american_scientific_journal-7186	57	50	to	to	ADP
american_scientific_journal-7186	57	51	stress	stress	NOUN
american_scientific_journal-7186	57	52	,	,	PUNCT
american_scientific_journal-7186	57	53	development	development	NOUN
american_scientific_journal-7186	57	54	and	and	CCONJ
american_scientific_journal-7186	57	55	many	many	ADJ
american_scientific_journal-7186	57	56	other	other	ADJ
american_scientific_journal-7186	57	57	biological	biological	ADJ
american_scientific_journal-7186	57	58	features	feature	NOUN
american_scientific_journal-7186	57	59	[	[	X
american_scientific_journal-7186	57	60	8	8	NUM
american_scientific_journal-7186	57	61	]	]	PUNCT
american_scientific_journal-7186	57	62	.	.	PUNCT
american_scientific_journal-7186	58	1	1.3	1.3	NUM
american_scientific_journal-7186	58	2	.	.	PUNCT
american_scientific_journal-7186	59	1	guide	guide	VERB
american_scientific_journal-7186	59	2	rna	rna	NOUN
american_scientific_journal-7186	59	3	expression	expression	NOUN
american_scientific_journal-7186	59	4	1.3.1	1.3.1	NUM
american_scientific_journal-7186	59	5	.	.	PUNCT
american_scientific_journal-7186	59	6	regulation	regulation	NOUN
american_scientific_journal-7186	59	7	of	of	ADP
american_scientific_journal-7186	59	8	grna	grna	NOUN
american_scientific_journal-7186	59	9	by	by	ADP
american_scientific_journal-7186	59	10	promoter	promoter	NOUN
american_scientific_journal-7186	59	11	of	of	ADP
american_scientific_journal-7186	59	12	rna	rna	PROPN
american_scientific_journal-7186	59	13	polymeraseiii	polymeraseiii	NOUN
american_scientific_journal-7186	59	14	and	and	CCONJ
american_scientific_journal-7186	59	15	polymeraseii	polymeraseii	ADJ
american_scientific_journal-7186	59	16	grna	grna	NOUN
american_scientific_journal-7186	59	17	which	which	PRON
american_scientific_journal-7186	59	18	is	be	AUX
american_scientific_journal-7186	59	19	present	present	ADJ
american_scientific_journal-7186	59	20	in	in	ADP
american_scientific_journal-7186	59	21	crispr	crispr	ADJ
american_scientific_journal-7186	59	22	/	/	SYM
american_scientific_journal-7186	59	23	cas9	cas9	NOUN
american_scientific_journal-7186	59	24	lack	lack	NOUN
american_scientific_journal-7186	59	25	poly	poly	VERB
american_scientific_journal-7186	59	26	a	a	DET
american_scientific_journal-7186	59	27	tail	tail	NOUN
american_scientific_journal-7186	59	28	as	as	ADV
american_scientific_journal-7186	59	29	well	well	ADV
american_scientific_journal-7186	59	30	as	as	ADP
american_scientific_journal-7186	59	31	the	the	DET
american_scientific_journal-7186	59	32	cap	cap	NOUN
american_scientific_journal-7186	59	33	structure	structure	NOUN
american_scientific_journal-7186	59	34	.	.	PUNCT
american_scientific_journal-7186	60	1	mostly	mostly	ADV
american_scientific_journal-7186	60	2	grna	grna	NOUN
american_scientific_journal-7186	60	3	is	be	AUX
american_scientific_journal-7186	60	4	regulated	regulate	VERB
american_scientific_journal-7186	60	5	by	by	ADP
american_scientific_journal-7186	60	6	the	the	DET
american_scientific_journal-7186	60	7	u6	u6	ADJ
american_scientific_journal-7186	60	8	promoter	promoter	NOUN
american_scientific_journal-7186	60	9	of	of	ADP
american_scientific_journal-7186	60	10	rnapolymerase	rnapolymerase	PROPN
american_scientific_journal-7186	60	11	iii	iii	PROPN
american_scientific_journal-7186	60	12	.	.	PUNCT
american_scientific_journal-7186	61	1	it	it	PRON
american_scientific_journal-7186	61	2	is	be	AUX
american_scientific_journal-7186	61	3	persistence	persistence	NOUN
american_scientific_journal-7186	61	4	and	and	CCONJ
american_scientific_journal-7186	61	5	have	have	VERB
american_scientific_journal-7186	61	6	base	base	NOUN
american_scientific_journal-7186	61	7	priority	priority	NOUN
american_scientific_journal-7186	61	8	in	in	ADP
american_scientific_journal-7186	61	9	driving	driving	NOUN
american_scientific_journal-7186	61	10	process	process	NOUN
american_scientific_journal-7186	61	11	of	of	ADP
american_scientific_journal-7186	61	12	transcription	transcription	NOUN
american_scientific_journal-7186	61	13	[	[	X
american_scientific_journal-7186	61	14	9	9	NUM
american_scientific_journal-7186	61	15	]	]	PUNCT
american_scientific_journal-7186	61	16	.	.	PUNCT
american_scientific_journal-7186	62	1	the	the	DET
american_scientific_journal-7186	62	2	analysis	analysis	NOUN
american_scientific_journal-7186	62	3	of	of	ADP
american_scientific_journal-7186	62	4	bioinformatics	bioinformatics	NOUN
american_scientific_journal-7186	62	5	reported	report	VERB
american_scientific_journal-7186	62	6	that	that	SCONJ
american_scientific_journal-7186	62	7	from	from	ADP
american_scientific_journal-7186	62	8	yeast	yeast	NOUN
american_scientific_journal-7186	62	9	to	to	ADP
american_scientific_journal-7186	62	10	mammal	mammal	PROPN
american_scientific_journal-7186	62	11	’s	’s	PART
american_scientific_journal-7186	62	12	genes	gene	NOUN
american_scientific_journal-7186	62	13	of	of	ADP
american_scientific_journal-7186	62	14	u6	u6	ADJ
american_scientific_journal-7186	62	15	small	small	ADJ
american_scientific_journal-7186	62	16	nuclear	nuclear	ADJ
american_scientific_journal-7186	62	17	rna	rna	NOUN
american_scientific_journal-7186	62	18	(	(	PUNCT
american_scientific_journal-7186	62	19	snrna	snrna	ADJ
american_scientific_journal-7186	62	20	)	)	PUNCT
american_scientific_journal-7186	62	21	are	be	AUX
american_scientific_journal-7186	62	22	much	much	ADV
american_scientific_journal-7186	62	23	conserved	conserve	VERB
american_scientific_journal-7186	62	24	.	.	PUNCT
american_scientific_journal-7186	63	1	in	in	ADP
american_scientific_journal-7186	63	2	many	many	ADJ
american_scientific_journal-7186	63	3	filamentous	filamentous	ADJ
american_scientific_journal-7186	63	4	fungi	fungus	NOUN
american_scientific_journal-7186	63	5	system	system	NOUN
american_scientific_journal-7186	63	6	of	of	ADP
american_scientific_journal-7186	63	7	crispr	crispr	NOUN
american_scientific_journal-7186	63	8	/	/	SYM
american_scientific_journal-7186	63	9	cas9	cas9	NOUN
american_scientific_journal-7186	63	10	having	have	VERB
american_scientific_journal-7186	63	11	u6	u6	ADJ
american_scientific_journal-7186	63	12	promoter	promoter	NOUN
american_scientific_journal-7186	63	13	for	for	ADP
american_scientific_journal-7186	63	14	transcription	transcription	NOUN
american_scientific_journal-7186	63	15	of	of	ADP
american_scientific_journal-7186	63	16	grna	grna	NOUN
american_scientific_journal-7186	63	17	is	be	AUX
american_scientific_journal-7186	63	18	used	use	VERB
american_scientific_journal-7186	63	19	[	[	PUNCT
american_scientific_journal-7186	63	20	10	10	NUM
american_scientific_journal-7186	63	21	]	]	PUNCT
american_scientific_journal-7186	63	22	.	.	PUNCT
american_scientific_journal-7186	64	1	the	the	DET
american_scientific_journal-7186	64	2	system	system	NOUN
american_scientific_journal-7186	64	3	of	of	ADP
american_scientific_journal-7186	64	4	crispr	crispr	NOUN
american_scientific_journal-7186	64	5	/	/	SYM
american_scientific_journal-7186	64	6	cas9	cas9	NOUN
american_scientific_journal-7186	64	7	was	be	AUX
american_scientific_journal-7186	64	8	also	also	ADV
american_scientific_journal-7186	64	9	optimized	optimize	VERB
american_scientific_journal-7186	64	10	and	and	CCONJ
american_scientific_journal-7186	64	11	efficiency	efficiency	NOUN
american_scientific_journal-7186	64	12	of	of	ADP
american_scientific_journal-7186	64	13	expression	expression	NOUN
american_scientific_journal-7186	64	14	of	of	ADP
american_scientific_journal-7186	64	15	trna	trna	PROPN
american_scientific_journal-7186	64	16	promoter	promoter	NOUN
american_scientific_journal-7186	64	17	was	be	AUX
american_scientific_journal-7186	64	18	tested	test	VERB
american_scientific_journal-7186	64	19	.	.	PUNCT
american_scientific_journal-7186	65	1	there	there	PRON
american_scientific_journal-7186	65	2	are	be	VERB
american_scientific_journal-7186	65	3	four	four	NUM
american_scientific_journal-7186	65	4	trna	trna	NOUN
american_scientific_journal-7186	65	5	promoter	promoter	NOUN
american_scientific_journal-7186	65	6	i.e.	i.e.	X
american_scientific_journal-7186	65	7	ptrnaglytcc	ptrnaglytcc	NOUN
american_scientific_journal-7186	65	8	,	,	PUNCT
american_scientific_journal-7186	65	9	ptrnatyrgta	ptrnatyrgta	NOUN
american_scientific_journal-7186	65	10	,	,	PUNCT
american_scientific_journal-7186	65	11	ptrnaglygcc	ptrnaglygcc	NOUN
american_scientific_journal-7186	65	12	and	and	CCONJ
american_scientific_journal-7186	65	13	ptrnaleu	ptrnaleu	NOUN
american_scientific_journal-7186	65	14	-	-	PUNCT
american_scientific_journal-7186	65	15	taa	taa	NOUN
american_scientific_journal-7186	65	16	.	.	PUNCT
american_scientific_journal-7186	66	1	the	the	DET
american_scientific_journal-7186	66	2	efficiency	efficiency	NOUN
american_scientific_journal-7186	66	3	of	of	ADP
american_scientific_journal-7186	66	4	these	these	DET
american_scientific_journal-7186	66	5	promoters	promoter	NOUN
american_scientific_journal-7186	66	6	is	be	AUX
american_scientific_journal-7186	66	7	very	very	ADV
american_scientific_journal-7186	66	8	high	high	ADJ
american_scientific_journal-7186	66	9	than	than	ADP
american_scientific_journal-7186	66	10	others	other	NOUN
american_scientific_journal-7186	66	11	u6	u6	ADJ
american_scientific_journal-7186	66	12	promoter	promoter	NOUN
american_scientific_journal-7186	66	13	.	.	PUNCT
american_scientific_journal-7186	67	1	it	it	PRON
american_scientific_journal-7186	67	2	shows	show	VERB
american_scientific_journal-7186	67	3	that	that	SCONJ
american_scientific_journal-7186	67	4	promoter	promoter	NOUN
american_scientific_journal-7186	67	5	of	of	ADP
american_scientific_journal-7186	67	6	trna	trna	PROPN
american_scientific_journal-7186	67	7	can	can	AUX
american_scientific_journal-7186	67	8	be	be	AUX
american_scientific_journal-7186	67	9	useful	useful	ADJ
american_scientific_journal-7186	67	10	for	for	ADP
american_scientific_journal-7186	67	11	expression	expression	NOUN
american_scientific_journal-7186	67	12	of	of	ADP
american_scientific_journal-7186	67	13	grna	grna	NOUN
american_scientific_journal-7186	67	14	as	as	ADV
american_scientific_journal-7186	67	15	well	well	ADV
american_scientific_journal-7186	67	16	.	.	PUNCT
american_scientific_journal-7186	68	1	the	the	DET
american_scientific_journal-7186	68	2	efficiency	efficiency	NOUN
american_scientific_journal-7186	68	3	of	of	ADP
american_scientific_journal-7186	68	4	various	various	ADJ
american_scientific_journal-7186	68	5	promoter	promoter	NOUN
american_scientific_journal-7186	68	6	of	of	ADP
american_scientific_journal-7186	68	7	trna	trna	PROPN
american_scientific_journal-7186	68	8	are	be	AUX
american_scientific_journal-7186	68	9	depended	depend	VERB
american_scientific_journal-7186	68	10	of	of	ADP
american_scientific_journal-7186	68	11	stain	stain	NOUN
american_scientific_journal-7186	68	12	.	.	PUNCT
american_scientific_journal-7186	69	1	in	in	ADP
american_scientific_journal-7186	69	2	various	various	ADJ
american_scientific_journal-7186	69	3	cases	case	NOUN
american_scientific_journal-7186	69	4	,	,	PUNCT
american_scientific_journal-7186	69	5	efficiency	efficiency	NOUN
american_scientific_journal-7186	69	6	of	of	ADP
american_scientific_journal-7186	69	7	the	the	DET
american_scientific_journal-7186	69	8	genome	genome	NOUN
american_scientific_journal-7186	69	9	editing	editing	NOUN
american_scientific_journal-7186	69	10	which	which	PRON
american_scientific_journal-7186	69	11	is	be	AUX
american_scientific_journal-7186	69	12	based	base	VERB
american_scientific_journal-7186	69	13	on	on	ADP
american_scientific_journal-7186	69	14	trna	trna	PROPN
american_scientific_journal-7186	69	15	remains	remain	VERB
american_scientific_journal-7186	69	16	debatable	debatable	ADJ
american_scientific_journal-7186	69	17	.	.	PUNCT
american_scientific_journal-7186	70	1	for	for	ADP
american_scientific_journal-7186	70	2	effective	effective	ADJ
american_scientific_journal-7186	70	3	expression	expression	NOUN
american_scientific_journal-7186	70	4	of	of	ADP
american_scientific_journal-7186	70	5	grna	grna	NOUN
american_scientific_journal-7186	70	6	the	the	DET
american_scientific_journal-7186	70	7	gene	gene	NOUN
american_scientific_journal-7186	70	8	of	of	ADP
american_scientific_journal-7186	70	9	5srrna	5srrna	PROPN
american_scientific_journal-7186	70	10	is	be	AUX
american_scientific_journal-7186	70	11	used	use	VERB
american_scientific_journal-7186	70	12	as	as	ADP
american_scientific_journal-7186	70	13	a	a	DET
american_scientific_journal-7186	70	14	promoter	promoter	NOUN
american_scientific_journal-7186	70	15	.	.	PUNCT
american_scientific_journal-7186	71	1	for	for	ADP
american_scientific_journal-7186	71	2	expression	expression	NOUN
american_scientific_journal-7186	71	3	of	of	ADP
american_scientific_journal-7186	71	4	the	the	DET
american_scientific_journal-7186	71	5	sgrna	sgrna	ADJ
american_scientific_journal-7186	71	6	38bp	38bp	ADJ
american_scientific_journal-7186	71	7	nucleotides	nucleotide	NOUN
american_scientific_journal-7186	71	8	sequence	sequence	NOUN
american_scientific_journal-7186	71	9	present	present	ADJ
american_scientific_journal-7186	71	10	at	at	ADP
american_scientific_journal-7186	71	11	upstream	upstream	ADJ
american_scientific_journal-7186	71	12	site	site	NOUN
american_scientific_journal-7186	71	13	of	of	ADP
american_scientific_journal-7186	71	14	5srrna	5srrna	NUM
american_scientific_journal-7186	71	15	gene	gene	NOUN
american_scientific_journal-7186	71	16	are	be	AUX
american_scientific_journal-7186	71	17	fused	fuse	VERB
american_scientific_journal-7186	71	18	with	with	ADP
american_scientific_journal-7186	71	19	sgrna	sgrna	ADJ
american_scientific_journal-7186	71	20	sequence	sequence	NOUN
american_scientific_journal-7186	71	21	to	to	PART
american_scientific_journal-7186	71	22	make	make	VERB
american_scientific_journal-7186	71	23	cassette	cassette	NOUN
american_scientific_journal-7186	71	24	expression	expression	NOUN
american_scientific_journal-7186	71	25	of	of	ADP
american_scientific_journal-7186	71	26	sgrna	sgrna	NOUN
american_scientific_journal-7186	71	27	[	[	X
american_scientific_journal-7186	71	28	11	11	NUM
american_scientific_journal-7186	71	29	]	]	PUNCT
american_scientific_journal-7186	71	30	.	.	PUNCT
american_scientific_journal-7186	72	1	there	there	PRON
american_scientific_journal-7186	72	2	are	be	VERB
american_scientific_journal-7186	72	3	many	many	ADJ
american_scientific_journal-7186	72	4	limitaions	limitaion	NOUN
american_scientific_journal-7186	72	5	of	of	ADP
american_scientific_journal-7186	72	6	transcription	transcription	NOUN
american_scientific_journal-7186	72	7	of	of	ADP
american_scientific_journal-7186	72	8	grna	grna	NOUN
american_scientific_journal-7186	72	9	by	by	ADP
american_scientific_journal-7186	72	10	u6	u6	ADJ
american_scientific_journal-7186	72	11	and	and	CCONJ
american_scientific_journal-7186	72	12	u3	u3	NOUN
american_scientific_journal-7186	72	13	promoters	promoter	NOUN
american_scientific_journal-7186	72	14	.	.	PUNCT
american_scientific_journal-7186	73	1	in	in	ADP
american_scientific_journal-7186	73	2	most	most	ADJ
american_scientific_journal-7186	73	3	organisms	organism	NOUN
american_scientific_journal-7186	73	4	these	these	DET
american_scientific_journal-7186	73	5	promoter	promoter	NOUN
american_scientific_journal-7186	73	6	are	be	AUX
american_scientific_journal-7186	73	7	transcribe	transcribe	VERB
american_scientific_journal-7186	73	8	by	by	ADP
american_scientific_journal-7186	73	9	using	use	VERB
american_scientific_journal-7186	73	10	rnapoliii	rnapoliii	NOUN
american_scientific_journal-7186	73	11	.	.	PUNCT
american_scientific_journal-7186	74	1	first	first	ADV
american_scientific_journal-7186	74	2	,	,	PUNCT
american_scientific_journal-7186	74	3	u3snrna	u3snrna	ADJ
american_scientific_journal-7186	74	4	and	and	CCONJ
american_scientific_journal-7186	74	5	u6snrna	u6snrna	NOUN
american_scientific_journal-7186	74	6	are	be	AUX
american_scientific_journal-7186	74	7	called	call	VERB
american_scientific_journal-7186	74	8	housekeeping	housekeeping	NOUN
american_scientific_journal-7186	74	9	gene	gene	NOUN
american_scientific_journal-7186	74	10	that	that	PRON
american_scientific_journal-7186	74	11	means	mean	VERB
american_scientific_journal-7186	74	12	they	they	PRON
american_scientific_journal-7186	74	13	are	be	AUX
american_scientific_journal-7186	74	14	expressed	express	VERB
american_scientific_journal-7186	74	15	ubiquitously	ubiquitously	ADV
american_scientific_journal-7186	74	16	.	.	PUNCT
american_scientific_journal-7186	75	1	therefore	therefore	ADV
american_scientific_journal-7186	75	2	they	they	PRON
american_scientific_journal-7186	75	3	are	be	AUX
american_scientific_journal-7186	75	4	not	not	PART
american_scientific_journal-7186	75	5	able	able	ADJ
american_scientific_journal-7186	75	6	to	to	PART
american_scientific_journal-7186	75	7	produce	produce	VERB
american_scientific_journal-7186	75	8	tissue	tissue	NOUN
american_scientific_journal-7186	75	9	specific	specific	ADJ
american_scientific_journal-7186	75	10	as	as	ADV
american_scientific_journal-7186	75	11	well	well	ADV
american_scientific_journal-7186	75	12	as	as	ADP
american_scientific_journal-7186	75	13	cell	cell	NOUN
american_scientific_journal-7186	75	14	specific	specific	ADJ
american_scientific_journal-7186	75	15	grna	grna	NOUN
american_scientific_journal-7186	75	16	.	.	PUNCT
american_scientific_journal-7186	76	1	second	second	ADJ
american_scientific_journal-7186	76	2	,	,	PUNCT
american_scientific_journal-7186	76	3	due	due	ADP
american_scientific_journal-7186	76	4	to	to	ADP
american_scientific_journal-7186	76	5	unavailability	unavailability	NOUN
american_scientific_journal-7186	76	6	of	of	ADP
american_scientific_journal-7186	76	7	polymerase	polymerase	NOUN
american_scientific_journal-7186	76	8	3	3	NUM
american_scientific_journal-7186	76	9	at	at	ADP
american_scientific_journal-7186	76	10	commercial	commercial	ADJ
american_scientific_journal-7186	76	11	level	level	NOUN
american_scientific_journal-7186	76	12	the	the	DET
american_scientific_journal-7186	76	13	use	use	NOUN
american_scientific_journal-7186	76	14	of	of	ADP
american_scientific_journal-7186	76	15	u3	u3	NOUN
american_scientific_journal-7186	76	16	and	and	CCONJ
american_scientific_journal-7186	76	17	u6	u6	ADJ
american_scientific_journal-7186	76	18	promoter	promoter	NOUN
american_scientific_journal-7186	76	19	in	in	ADP
american_scientific_journal-7186	76	20	traditional	traditional	ADJ
american_scientific_journal-7186	76	21	invitro	invitro	ADJ
american_scientific_journal-7186	76	22	gene	gene	NOUN
american_scientific_journal-7186	76	23	transcription	transcription	NOUN
american_scientific_journal-7186	76	24	of	of	ADP
american_scientific_journal-7186	76	25	sgrna	sgrna	NOUN
american_scientific_journal-7186	76	26	is	be	AUX
american_scientific_journal-7186	76	27	not	not	PART
american_scientific_journal-7186	76	28	propitious	propitious	ADJ
american_scientific_journal-7186	76	29	[	[	X
american_scientific_journal-7186	76	30	12	12	NUM
american_scientific_journal-7186	76	31	]	]	PUNCT
american_scientific_journal-7186	76	32	.	.	PUNCT
american_scientific_journal-7186	77	1	ribozymes	ribozyme	NOUN
american_scientific_journal-7186	77	2	have	have	VERB
american_scientific_journal-7186	77	3	nucleases	nuclease	NOUN
american_scientific_journal-7186	77	4	activity	activity	NOUN
american_scientific_journal-7186	77	5	and	and	CCONJ
american_scientific_journal-7186	77	6	it	it	PRON
american_scientific_journal-7186	77	7	is	be	AUX
american_scientific_journal-7186	77	8	use	use	NOUN
american_scientific_journal-7186	77	9	to	to	PART
american_scientific_journal-7186	77	10	construct	construct	VERB
american_scientific_journal-7186	77	11	an	an	DET
american_scientific_journal-7186	77	12	artificial	artificial	ADJ
american_scientific_journal-7186	77	13	rgr	rgr	NOUN
american_scientific_journal-7186	77	14	gene	gene	NOUN
american_scientific_journal-7186	77	15	(	(	PUNCT
american_scientific_journal-7186	77	16	ribozyme	ribozyme	NOUN
american_scientific_journal-7186	77	17	-	-	PUNCT
american_scientific_journal-7186	77	18	grna	grna	NOUN
american_scientific_journal-7186	77	19	-	-	PUNCT
american_scientific_journal-7186	77	20	ribizyme	ribizyme	NOUN
american_scientific_journal-7186	77	21	u6snrna	u6snrna	NOUN
american_scientific_journal-7186	77	22	)	)	PUNCT
american_scientific_journal-7186	77	23	.	.	PUNCT
american_scientific_journal-7186	78	1	at	at	ADP
american_scientific_journal-7186	78	2	3′	3′	NUM
american_scientific_journal-7186	78	3	terminal	terminal	NOUN
american_scientific_journal-7186	78	4	there	there	PRON
american_scientific_journal-7186	78	5	is	be	VERB
american_scientific_journal-7186	78	6	a	a	DET
american_scientific_journal-7186	78	7	hepatitis	hepatitis	NOUN
american_scientific_journal-7186	78	8	d	d	NOUN
american_scientific_journal-7186	78	9	virus	virus	NOUN
american_scientific_journal-7186	78	10	(	(	PUNCT
american_scientific_journal-7186	78	11	hdv	hdv	PROPN
american_scientific_journal-7186	78	12	)	)	PUNCT
american_scientific_journal-7186	78	13	and	and	CCONJ
american_scientific_journal-7186	78	14	at	at	ADP
american_scientific_journal-7186	78	15	5′-terminal	5′-terminal	PROPN
american_scientific_journal-7186	78	16	there	there	PRON
american_scientific_journal-7186	78	17	is	be	VERB
american_scientific_journal-7186	78	18	a	a	DET
american_scientific_journal-7186	78	19	hammerhead	hammerhead	NOUN
american_scientific_journal-7186	78	20	(	(	PUNCT
american_scientific_journal-7186	78	21	hh	hh	PROPN
american_scientific_journal-7186	78	22	)	)	PUNCT
american_scientific_journal-7186	78	23	.	.	PUNCT
american_scientific_journal-7186	79	1	under	under	ADP
american_scientific_journal-7186	79	2	control	control	NOUN
american_scientific_journal-7186	79	3	of	of	ADP
american_scientific_journal-7186	79	4	rna	rna	PROPN
american_scientific_journal-7186	79	5	polymerase	polymerase	NOUN
american_scientific_journal-7186	79	6	ii	ii	PROPN
american_scientific_journal-7186	79	7	in	in	ADP
american_scientific_journal-7186	79	8	yeast	yeast	NOUN
american_scientific_journal-7186	79	9	this	this	DET
american_scientific_journal-7186	79	10	system	system	NOUN
american_scientific_journal-7186	79	11	was	be	AUX
american_scientific_journal-7186	79	12	introduce	introduce	ADJ
american_scientific_journal-7186	79	13	.	.	PUNCT
american_scientific_journal-7186	80	1	to	to	PART
american_scientific_journal-7186	80	2	complete	complete	VERB
american_scientific_journal-7186	80	3	the	the	DET
american_scientific_journal-7186	80	4	cleavage	cleavage	NOUN
american_scientific_journal-7186	80	5	of	of	ADP
american_scientific_journal-7186	80	6	targeted	target	VERB
american_scientific_journal-7186	80	7	dna	dna	NOUN
american_scientific_journal-7186	80	8	transcription	transcription	NOUN
american_scientific_journal-7186	80	9	of	of	ADP
american_scientific_journal-7186	80	10	adhi	adhi	PROPN
american_scientific_journal-7186	80	11	gene	gene	NOUN
american_scientific_journal-7186	80	12	by	by	ADP
american_scientific_journal-7186	80	13	pol	pol	PROPN
american_scientific_journal-7186	80	14	ii	ii	PROPN
american_scientific_journal-7186	80	15	.	.	PUNCT
american_scientific_journal-7186	81	1	ribozyme	ribozyme	PROPN
american_scientific_journal-7186	81	2	-	-	PUNCT
american_scientific_journal-7186	81	3	grnaribozyme	grnaribozyme	NOUN
american_scientific_journal-7186	81	4	is	be	AUX
american_scientific_journal-7186	81	5	constructed	construct	VERB
american_scientific_journal-7186	81	6	by	by	ADP
american_scientific_journal-7186	81	7	using	use	VERB
american_scientific_journal-7186	81	8	the	the	DET
american_scientific_journal-7186	81	9	terminator	terminator	NOUN
american_scientific_journal-7186	81	10	of	of	ADP
american_scientific_journal-7186	81	11	trpc	trpc	NOUN
american_scientific_journal-7186	81	12	(	(	PUNCT
american_scientific_journal-7186	81	13	ttrpc	ttrpc	ADV
american_scientific_journal-7186	81	14	)	)	PUNCT
american_scientific_journal-7186	81	15	and	and	CCONJ
american_scientific_journal-7186	81	16	by	by	ADP
american_scientific_journal-7186	81	17	using	use	VERB
american_scientific_journal-7186	81	18	promoter	promoter	NOUN
american_scientific_journal-7186	81	19	of	of	ADP
american_scientific_journal-7186	81	20	gpda	gpda	NOUN
american_scientific_journal-7186	81	21	(	(	PUNCT
american_scientific_journal-7186	81	22	pgoda	pgoda	PROPN
american_scientific_journal-7186	81	23	)	)	PUNCT
american_scientific_journal-7186	81	24	.	.	PUNCT
american_scientific_journal-7186	82	1	it	it	PRON
american_scientific_journal-7186	82	2	was	be	AUX
american_scientific_journal-7186	82	3	applied	apply	VERB
american_scientific_journal-7186	82	4	in	in	ADP
american_scientific_journal-7186	82	5	the	the	DET
american_scientific_journal-7186	82	6	many	many	ADJ
american_scientific_journal-7186	82	7	filamentous	filamentous	ADJ
american_scientific_journal-7186	82	8	fungi	fungus	NOUN
american_scientific_journal-7186	82	9	very	very	ADV
american_scientific_journal-7186	82	10	successful	successful	ADJ
american_scientific_journal-7186	82	11	manner	manner	NOUN
american_scientific_journal-7186	82	12	.	.	PUNCT
american_scientific_journal-7186	83	1	1.4	1.4	NUM
american_scientific_journal-7186	83	2	.	.	PUNCT
american_scientific_journal-7186	83	3	delivery	delivery	NOUN
american_scientific_journal-7186	83	4	of	of	ADP
american_scientific_journal-7186	83	5	crispr	crispr	NOUN
american_scientific_journal-7186	83	6	/	/	SYM
american_scientific_journal-7186	83	7	cas9	cas9	NOUN
american_scientific_journal-7186	83	8	into	into	ADP
american_scientific_journal-7186	83	9	cells	cell	NOUN
american_scientific_journal-7186	83	10	of	of	ADP
american_scientific_journal-7186	83	11	fungi	fungus	NOUN
american_scientific_journal-7186	83	12	the	the	DET
american_scientific_journal-7186	83	13	system	system	NOUN
american_scientific_journal-7186	83	14	is	be	AUX
american_scientific_journal-7186	83	15	delivered	deliver	VERB
american_scientific_journal-7186	83	16	to	to	ADP
american_scientific_journal-7186	83	17	cell	cell	NOUN
american_scientific_journal-7186	83	18	by	by	ADP
american_scientific_journal-7186	83	19	using	use	VERB
american_scientific_journal-7186	83	20	the	the	DET
american_scientific_journal-7186	83	21	vector	vector	NOUN
american_scientific_journal-7186	83	22	carrying	carry	VERB
american_scientific_journal-7186	83	23	the	the	DET
american_scientific_journal-7186	83	24	expression	expression	NOUN
american_scientific_journal-7186	83	25	cassettes	cassette	NOUN
american_scientific_journal-7186	83	26	of	of	ADP
american_scientific_journal-7186	83	27	sgrna	sgrna	NOUN
american_scientific_journal-7186	83	28	and	and	CCONJ
american_scientific_journal-7186	83	29	cas9	cas9	NOUN
american_scientific_journal-7186	83	30	.	.	PUNCT
american_scientific_journal-7186	84	1	conventionally	conventionally	ADV
american_scientific_journal-7186	84	2	these	these	DET
american_scientific_journal-7186	84	3	cassettes	cassette	NOUN
american_scientific_journal-7186	84	4	(	(	PUNCT
american_scientific_journal-7186	84	5	cas9	cas9	NOUN
american_scientific_journal-7186	84	6	and	and	CCONJ
american_scientific_journal-7186	84	7	sgrna	sgrna	PROPN
american_scientific_journal-7186	84	8	)	)	PUNCT
american_scientific_journal-7186	84	9	are	be	AUX
american_scientific_journal-7186	84	10	carried	carry	VERB
american_scientific_journal-7186	84	11	into	into	ADP
american_scientific_journal-7186	84	12	double	double	ADJ
american_scientific_journal-7186	84	13	and	and	CCONJ
american_scientific_journal-7186	84	14	single	single	ADJ
american_scientific_journal-7186	84	15	vector	vector	NOUN
american_scientific_journal-7186	84	16	.	.	PUNCT
american_scientific_journal-7186	85	1	zhang	zhang	PROPN
american_scientific_journal-7186	85	2	and	and	CCONJ
american_scientific_journal-7186	85	3	his	his	PRON
american_scientific_journal-7186	85	4	colleagues	colleague	NOUN
american_scientific_journal-7186	85	5	(	(	PUNCT
american_scientific_journal-7186	85	6	2016	2016	NUM
american_scientific_journal-7186	85	7	)	)	PUNCT
american_scientific_journal-7186	85	8	confirmed	confirm	VERB
american_scientific_journal-7186	85	9	effectiveness	effectiveness	NOUN
american_scientific_journal-7186	85	10	of	of	ADP
american_scientific_journal-7186	85	11	these	these	DET
american_scientific_journal-7186	85	12	two	two	NUM
american_scientific_journal-7186	85	13	approaches	approach	NOUN
american_scientific_journal-7186	85	14	of	of	ADP
american_scientific_journal-7186	85	15	expression	expression	NOUN
american_scientific_journal-7186	85	16	in	in	ADP
american_scientific_journal-7186	85	17	model	model	NOUN
american_scientific_journal-7186	85	18	organism	organism	ADJ
american_scientific_journal-7186	85	19	aspergillus	aspergillus	NOUN
american_scientific_journal-7186	85	20	fumigatus	fumigatus	NOUN
american_scientific_journal-7186	85	21	.	.	PUNCT
american_scientific_journal-7186	86	1	he	he	PRON
american_scientific_journal-7186	86	2	reported	report	VERB
american_scientific_journal-7186	86	3	that	that	SCONJ
american_scientific_journal-7186	86	4	the	the	DET
american_scientific_journal-7186	86	5	efficiency	efficiency	NOUN
american_scientific_journal-7186	86	6	of	of	ADP
american_scientific_journal-7186	86	7	the	the	DET
american_scientific_journal-7186	86	8	vector	vector	NOUN
american_scientific_journal-7186	86	9	of	of	ADP
american_scientific_journal-7186	86	10	single	single	ADJ
american_scientific_journal-7186	86	11	expression	expression	NOUN
american_scientific_journal-7186	86	12	was	be	AUX
american_scientific_journal-7186	86	13	significantly	significantly	ADV
american_scientific_journal-7186	86	14	higher	high	ADJ
american_scientific_journal-7186	86	15	than	than	ADP
american_scientific_journal-7186	86	16	the	the	DET
american_scientific_journal-7186	86	17	double	double	ADJ
american_scientific_journal-7186	86	18	expression	expression	NOUN
american_scientific_journal-7186	86	19	vector	vector	NOUN
american_scientific_journal-7186	86	20	.	.	PUNCT
american_scientific_journal-7186	87	1	it	it	PRON
american_scientific_journal-7186	87	2	is	be	AUX
american_scientific_journal-7186	87	3	because	because	SCONJ
american_scientific_journal-7186	87	4	of	of	ADP
american_scientific_journal-7186	87	5	the	the	DET
american_scientific_journal-7186	87	6	transformation	transformation	NOUN
american_scientific_journal-7186	87	7	of	of	ADP
american_scientific_journal-7186	87	8	vector	vector	NOUN
american_scientific_journal-7186	87	9	in	in	ADP
american_scientific_journal-7186	87	10	cells	cell	NOUN
american_scientific_journal-7186	87	11	of	of	ADP
american_scientific_journal-7186	87	12	fungi	fungus	NOUN
american_scientific_journal-7186	87	13	can	can	AUX
american_scientific_journal-7186	87	14	not	not	PART
american_scientific_journal-7186	87	15	be	be	AUX
american_scientific_journal-7186	87	16	exactly	exactly	ADV
american_scientific_journal-7186	87	17	undercontrol	undercontrol	NOUN
american_scientific_journal-7186	87	18	.	.	PUNCT
american_scientific_journal-7186	88	1	there	there	ADV
american_scientific_journal-7186	88	2	two	two	NUM
american_scientific_journal-7186	88	3	methods	method	NOUN
american_scientific_journal-7186	88	4	for	for	ADP
american_scientific_journal-7186	88	5	the	the	DET
american_scientific_journal-7186	88	6	transformation	transformation	NOUN
american_scientific_journal-7186	88	7	of	of	ADP
american_scientific_journal-7186	88	8	crispr	crispr	ADJ
american_scientific_journal-7186	88	9	/	/	SYM
american_scientific_journal-7186	88	10	cas9	cas9	NOUN
american_scientific_journal-7186	88	11	in	in	ADP
american_scientific_journal-7186	88	12	to	to	ADP
american_scientific_journal-7186	88	13	cells	cell	NOUN
american_scientific_journal-7186	88	14	of	of	ADP
american_scientific_journal-7186	88	15	fungi	fungi	PROPN
american_scientific_journal-7186	88	16	.	.	PUNCT
american_scientific_journal-7186	89	1	1	1	NUM
american_scientific_journal-7186	89	2	)	)	PUNCT
american_scientific_journal-7186	89	3	agrobacterium	agrobacterium	NOUN
american_scientific_journal-7186	89	4	mediated	mediate	VERB
american_scientific_journal-7186	89	5	transformation	transformation	NOUN
american_scientific_journal-7186	89	6	(	(	PUNCT
american_scientific_journal-7186	89	7	amt	amt	PROPN
american_scientific_journal-7186	89	8	)	)	PUNCT
american_scientific_journal-7186	89	9	2	2	NUM
american_scientific_journal-7186	89	10	)	)	PUNCT
american_scientific_journal-7186	89	11	polyethylene	polyethylene	NOUN
american_scientific_journal-7186	89	12	glycol	glycol	NOUN
american_scientific_journal-7186	89	13	(	(	PUNCT
american_scientific_journal-7186	89	14	peg	peg	NOUN
american_scientific_journal-7186	89	15	)	)	PUNCT
american_scientific_journal-7186	89	16	transformation	transformation	NOUN
american_scientific_journal-7186	89	17	.	.	PUNCT
american_scientific_journal-7186	90	1	many	many	ADJ
american_scientific_journal-7186	90	2	studies	study	NOUN
american_scientific_journal-7186	90	3	reported	report	VERB
american_scientific_journal-7186	90	4	poly	poly	ADJ
american_scientific_journal-7186	90	5	ethylene	ethylene	NOUN
american_scientific_journal-7186	90	6	glycol	glycol	NOUN
american_scientific_journal-7186	90	7	is	be	AUX
american_scientific_journal-7186	90	8	most	most	ADV
american_scientific_journal-7186	90	9	convenient	convenient	ADJ
american_scientific_journal-7186	90	10	methods	method	NOUN
american_scientific_journal-7186	90	11	for	for	ADP
american_scientific_journal-7186	90	12	transformation	transformation	NOUN
american_scientific_journal-7186	90	13	of	of	ADP
american_scientific_journal-7186	90	14	cassettes	cassette	NOUN
american_scientific_journal-7186	90	15	of	of	ADP
american_scientific_journal-7186	90	16	grna	grna	NOUN
american_scientific_journal-7186	90	17	and	and	CCONJ
american_scientific_journal-7186	90	18	cas9	cas9	NOUN
american_scientific_journal-7186	90	19	into	into	ADP
american_scientific_journal-7186	90	20	cells	cell	NOUN
american_scientific_journal-7186	90	21	of	of	ADP
american_scientific_journal-7186	90	22	fungi	fungi	PROPN
american_scientific_journal-7186	90	23	[	[	X
american_scientific_journal-7186	90	24	12	12	NUM
american_scientific_journal-7186	90	25	]	]	PUNCT
american_scientific_journal-7186	90	26	.	.	PUNCT
american_scientific_journal-7186	91	1	for	for	ADP
american_scientific_journal-7186	91	2	conventional	conventional	ADJ
american_scientific_journal-7186	91	3	editing	editing	NOUN
american_scientific_journal-7186	91	4	of	of	ADP
american_scientific_journal-7186	91	5	genome	genome	NOUN
american_scientific_journal-7186	91	6	the	the	DET
american_scientific_journal-7186	91	7	most	most	ADV
american_scientific_journal-7186	91	8	common	common	ADJ
american_scientific_journal-7186	91	9	method	method	NOUN
american_scientific_journal-7186	91	10	is	be	AUX
american_scientific_journal-7186	91	11	argobacterium	argobacterium	NOUN
american_scientific_journal-7186	91	12	mediated	mediate	VERB
american_scientific_journal-7186	91	13	transformation	transformation	NOUN
american_scientific_journal-7186	91	14	.	.	PUNCT
american_scientific_journal-7186	92	1	american	american	ADJ
american_scientific_journal-7186	92	2	academic	academic	ADJ
american_scientific_journal-7186	92	3	scientific	scientific	ADJ
american_scientific_journal-7186	92	4	research	research	NOUN
american_scientific_journal-7186	92	5	journal	journal	NOUN
american_scientific_journal-7186	92	6	for	for	ADP
american_scientific_journal-7186	92	7	engineering	engineering	NOUN
american_scientific_journal-7186	92	8	,	,	PUNCT
american_scientific_journal-7186	92	9	technology	technology	NOUN
american_scientific_journal-7186	92	10	,	,	PUNCT
american_scientific_journal-7186	92	11	and	and	CCONJ
american_scientific_journal-7186	92	12	sciences(asrjets	sciences(asrjet	NOUN
american_scientific_journal-7186	92	13	)	)	PUNCT
american_scientific_journal-7186	92	14	(	(	PUNCT
american_scientific_journal-7186	92	15	2022)volume	2022)volume	NUM
american_scientific_journal-7186	92	16	85	85	NUM
american_scientific_journal-7186	92	17	,	,	PUNCT
american_scientific_journal-7186	92	18	no	no	DET
american_scientific_journal-7186	92	19	1	1	NUM
american_scientific_journal-7186	92	20	,	,	PUNCT
american_scientific_journal-7186	92	21	pp	pp	ADV
american_scientific_journal-7186	92	22	313	313	NUM
american_scientific_journal-7186	92	23	-	-	SYM
american_scientific_journal-7186	92	24	318	318	NUM
american_scientific_journal-7186	92	25	316	316	NUM
american_scientific_journal-7186	92	26	but	but	CCONJ
american_scientific_journal-7186	92	27	for	for	ADP
american_scientific_journal-7186	92	28	the	the	DET
american_scientific_journal-7186	92	29	transformation	transformation	NOUN
american_scientific_journal-7186	92	30	crispr	crispr	ADJ
american_scientific_journal-7186	92	31	/	/	SYM
american_scientific_journal-7186	92	32	cas9	cas9	NOUN
american_scientific_journal-7186	92	33	argobacterium	argobacterium	NOUN
american_scientific_journal-7186	92	34	is	be	AUX
american_scientific_journal-7186	92	35	not	not	PART
american_scientific_journal-7186	92	36	a	a	DET
american_scientific_journal-7186	92	37	frequently	frequently	ADV
american_scientific_journal-7186	92	38	use	use	VERB
american_scientific_journal-7186	92	39	method	method	NOUN
american_scientific_journal-7186	92	40	.	.	PUNCT
american_scientific_journal-7186	93	1	many	many	ADJ
american_scientific_journal-7186	93	2	studies	study	NOUN
american_scientific_journal-7186	93	3	reported	report	VERB
american_scientific_journal-7186	93	4	that	that	SCONJ
american_scientific_journal-7186	93	5	argobacterium	argobacterium	NOUN
american_scientific_journal-7186	93	6	is	be	AUX
american_scientific_journal-7186	93	7	most	most	ADV
american_scientific_journal-7186	93	8	convenient	convenient	ADJ
american_scientific_journal-7186	93	9	method	method	NOUN
american_scientific_journal-7186	93	10	for	for	ADP
american_scientific_journal-7186	93	11	genome	genome	NOUN
american_scientific_journal-7186	93	12	editing	editing	NOUN
american_scientific_journal-7186	93	13	of	of	ADP
american_scientific_journal-7186	93	14	many	many	ADJ
american_scientific_journal-7186	93	15	fungi	fungus	NOUN
american_scientific_journal-7186	93	16	.	.	PUNCT
american_scientific_journal-7186	94	1	1.5	1.5	NUM
american_scientific_journal-7186	94	2	.	.	PUNCT
american_scientific_journal-7186	95	1	regulation	regulation	NOUN
american_scientific_journal-7186	95	2	of	of	ADP
american_scientific_journal-7186	95	3	hr	hr	NOUN
american_scientific_journal-7186	95	4	and	and	CCONJ
american_scientific_journal-7186	95	5	nhej	nhej	ADJ
american_scientific_journal-7186	95	6	pathway	pathway	NOUN
american_scientific_journal-7186	95	7	cas9	cas9	PROPN
american_scientific_journal-7186	95	8	generated	generate	VERB
american_scientific_journal-7186	95	9	the	the	DET
american_scientific_journal-7186	95	10	double	double	ADJ
american_scientific_journal-7186	95	11	standard	standard	ADJ
american_scientific_journal-7186	95	12	breaks	break	NOUN
american_scientific_journal-7186	95	13	can	can	AUX
american_scientific_journal-7186	95	14	be	be	AUX
american_scientific_journal-7186	95	15	exposed	expose	VERB
american_scientific_journal-7186	95	16	to	to	ADP
american_scientific_journal-7186	95	17	mutagenesis	mutagenesis	VERB
american_scientific_journal-7186	95	18	by	by	ADP
american_scientific_journal-7186	95	19	nhej	nhej	ADJ
american_scientific_journal-7186	95	20	.	.	PUNCT
american_scientific_journal-7186	96	1	if	if	SCONJ
american_scientific_journal-7186	96	2	the	the	DET
american_scientific_journal-7186	96	3	donor	donor	NOUN
american_scientific_journal-7186	96	4	dna	dna	NOUN
american_scientific_journal-7186	96	5	is	be	AUX
american_scientific_journal-7186	96	6	delivered	deliver	VERB
american_scientific_journal-7186	96	7	to	to	ADP
american_scientific_journal-7186	96	8	cells	cell	NOUN
american_scientific_journal-7186	96	9	another	another	DET
american_scientific_journal-7186	96	10	method	method	NOUN
american_scientific_journal-7186	96	11	of	of	ADP
american_scientific_journal-7186	96	12	repairing	repair	VERB
american_scientific_journal-7186	96	13	called	call	VERB
american_scientific_journal-7186	96	14	homology	homology	NOUN
american_scientific_journal-7186	96	15	repair	repair	NOUN
american_scientific_journal-7186	96	16	(	(	PUNCT
american_scientific_journal-7186	96	17	hr	hr	NOUN
american_scientific_journal-7186	96	18	)	)	PUNCT
american_scientific_journal-7186	96	19	can	can	AUX
american_scientific_journal-7186	96	20	be	be	AUX
american_scientific_journal-7186	96	21	attained	attain	VERB
american_scientific_journal-7186	96	22	.	.	PUNCT
american_scientific_journal-7186	97	1	the	the	DET
american_scientific_journal-7186	97	2	pathway	pathway	NOUN
american_scientific_journal-7186	97	3	of	of	ADP
american_scientific_journal-7186	97	4	homology	homology	NOUN
american_scientific_journal-7186	97	5	repair	repair	NOUN
american_scientific_journal-7186	97	6	is	be	AUX
american_scientific_journal-7186	97	7	different	different	ADJ
american_scientific_journal-7186	97	8	from	from	ADP
american_scientific_journal-7186	97	9	route	route	NOUN
american_scientific_journal-7186	97	10	of	of	ADP
american_scientific_journal-7186	97	11	repair	repair	NOUN
american_scientific_journal-7186	97	12	of	of	ADP
american_scientific_journal-7186	97	13	nher	nher	ADJ
american_scientific_journal-7186	97	14	.	.	PUNCT
american_scientific_journal-7186	98	1	the	the	DET
american_scientific_journal-7186	98	2	repair	repair	NOUN
american_scientific_journal-7186	98	3	mechanism	mechanism	NOUN
american_scientific_journal-7186	98	4	of	of	ADP
american_scientific_journal-7186	98	5	nhej	nhej	ADJ
american_scientific_journal-7186	98	6	with	with	ADP
american_scientific_journal-7186	98	7	low	low	ADJ
american_scientific_journal-7186	98	8	fidelity	fidelity	PROPN
american_scientific_journal-7186	98	9	can	can	AUX
american_scientific_journal-7186	98	10	take	take	VERB
american_scientific_journal-7186	98	11	place	place	NOUN
american_scientific_journal-7186	98	12	in	in	ADP
american_scientific_journal-7186	98	13	g1	g1	PROPN
american_scientific_journal-7186	98	14	phase	phase	NOUN
american_scientific_journal-7186	98	15	of	of	ADP
american_scientific_journal-7186	98	16	the	the	DET
american_scientific_journal-7186	98	17	cell	cell	NOUN
american_scientific_journal-7186	98	18	cycle	cycle	NOUN
american_scientific_journal-7186	98	19	.	.	PUNCT
american_scientific_journal-7186	99	1	the	the	DET
american_scientific_journal-7186	99	2	homology	homology	NOUN
american_scientific_journal-7186	99	3	repair	repair	NOUN
american_scientific_journal-7186	99	4	mechanism	mechanism	NOUN
american_scientific_journal-7186	99	5	has	have	VERB
american_scientific_journal-7186	99	6	high	high	ADJ
american_scientific_journal-7186	99	7	fidelity	fidelity	NOUN
american_scientific_journal-7186	99	8	rate	rate	NOUN
american_scientific_journal-7186	99	9	and	and	CCONJ
american_scientific_journal-7186	99	10	follows	follow	VERB
american_scientific_journal-7186	99	11	replication	replication	NOUN
american_scientific_journal-7186	99	12	of	of	ADP
american_scientific_journal-7186	99	13	dna	dna	NOUN
american_scientific_journal-7186	99	14	.	.	PUNCT
american_scientific_journal-7186	100	1	in	in	ADP
american_scientific_journal-7186	100	2	repair	repair	NOUN
american_scientific_journal-7186	100	3	method	method	NOUN
american_scientific_journal-7186	100	4	of	of	ADP
american_scientific_journal-7186	100	5	nhej	nhej	ADJ
american_scientific_journal-7186	100	6	,	,	PUNCT
american_scientific_journal-7186	100	7	it	it	PRON
american_scientific_journal-7186	100	8	directly	directly	ADV
american_scientific_journal-7186	100	9	attach	attach	VERB
american_scientific_journal-7186	100	10	to	to	PART
american_scientific_journal-7186	100	11	dsbs	dsbs	VERB
american_scientific_journal-7186	100	12	present	present	NOUN
american_scientific_journal-7186	100	13	at	at	ADP
american_scientific_journal-7186	100	14	terminals	terminal	NOUN
american_scientific_journal-7186	100	15	of	of	ADP
american_scientific_journal-7186	100	16	dna	dna	NOUN
american_scientific_journal-7186	100	17	.	.	PUNCT
american_scientific_journal-7186	101	1	two	two	NUM
american_scientific_journal-7186	101	2	protein	protein	NOUN
american_scientific_journal-7186	101	3	ku80	ku80	PROPN
american_scientific_journal-7186	101	4	and	and	CCONJ
american_scientific_journal-7186	101	5	ku70	ku70	PROPN
american_scientific_journal-7186	101	6	play	play	VERB
american_scientific_journal-7186	101	7	a	a	DET
american_scientific_journal-7186	101	8	vital	vital	ADJ
american_scientific_journal-7186	101	9	role	role	NOUN
american_scientific_journal-7186	101	10	for	for	ADP
american_scientific_journal-7186	101	11	the	the	DET
american_scientific_journal-7186	101	12	attachment	attachment	NOUN
american_scientific_journal-7186	101	13	of	of	ADP
american_scientific_journal-7186	101	14	nhej	nhej	ADJ
american_scientific_journal-7186	101	15	.	.	PUNCT
american_scientific_journal-7186	102	1	in	in	ADP
american_scientific_journal-7186	102	2	homology	homology	NOUN
american_scientific_journal-7186	102	3	repair	repair	NOUN
american_scientific_journal-7186	102	4	mechanism	mechanism	NOUN
american_scientific_journal-7186	102	5	,	,	PUNCT
american_scientific_journal-7186	102	6	it	it	PRON
american_scientific_journal-7186	102	7	requires	require	VERB
american_scientific_journal-7186	102	8	to	to	PART
american_scientific_journal-7186	102	9	offer	offer	VERB
american_scientific_journal-7186	102	10	a	a	DET
american_scientific_journal-7186	102	11	target	target	NOUN
american_scientific_journal-7186	102	12	site	site	NOUN
american_scientific_journal-7186	102	13	[	[	X
american_scientific_journal-7186	102	14	13	13	NUM
american_scientific_journal-7186	102	15	]	]	PUNCT
american_scientific_journal-7186	102	16	.	.	PUNCT
american_scientific_journal-7186	103	1	the	the	DET
american_scientific_journal-7186	103	2	system	system	NOUN
american_scientific_journal-7186	103	3	of	of	ADP
american_scientific_journal-7186	103	4	crispr	crispr	ADJ
american_scientific_journal-7186	103	5	/	/	SYM
american_scientific_journal-7186	103	6	cas9	cas9	NOUN
american_scientific_journal-7186	103	7	use	use	VERB
american_scientific_journal-7186	103	8	the	the	DET
american_scientific_journal-7186	103	9	homology	homology	NOUN
american_scientific_journal-7186	103	10	repair	repair	NOUN
american_scientific_journal-7186	103	11	method	method	NOUN
american_scientific_journal-7186	103	12	foe	foe	VERB
american_scientific_journal-7186	103	13	precise	precise	ADJ
american_scientific_journal-7186	103	14	editing	editing	NOUN
american_scientific_journal-7186	103	15	of	of	ADP
american_scientific_journal-7186	103	16	target	target	NOUN
american_scientific_journal-7186	103	17	.	.	PUNCT
american_scientific_journal-7186	104	1	the	the	DET
american_scientific_journal-7186	104	2	insertion	insertion	NOUN
american_scientific_journal-7186	104	3	of	of	ADP
american_scientific_journal-7186	104	4	a	a	DET
american_scientific_journal-7186	104	5	particular	particular	ADJ
american_scientific_journal-7186	104	6	sequence	sequence	NOUN
american_scientific_journal-7186	104	7	and	and	CCONJ
american_scientific_journal-7186	104	8	mutation	mutation	NOUN
american_scientific_journal-7186	104	9	at	at	ADP
american_scientific_journal-7186	104	10	targeted	target	VERB
american_scientific_journal-7186	104	11	site	site	NOUN
american_scientific_journal-7186	104	12	can	can	AUX
american_scientific_journal-7186	104	13	be	be	AUX
american_scientific_journal-7186	104	14	achieved	achieve	VERB
american_scientific_journal-7186	104	15	by	by	ADP
american_scientific_journal-7186	104	16	this	this	DET
american_scientific_journal-7186	104	17	method	method	NOUN
american_scientific_journal-7186	104	18	.	.	PUNCT
american_scientific_journal-7186	105	1	1.6	1.6	NUM
american_scientific_journal-7186	105	2	.	.	PUNCT
american_scientific_journal-7186	105	3	crispr	crispr	PROPN
american_scientific_journal-7186	105	4	/	/	SYM
american_scientific_journal-7186	105	5	cas9	cas9	NOUN
american_scientific_journal-7186	105	6	induce	induce	VERB
american_scientific_journal-7186	105	7	the	the	DET
american_scientific_journal-7186	105	8	mutation	mutation	NOUN
american_scientific_journal-7186	105	9	and	and	CCONJ
american_scientific_journal-7186	105	10	off	off	ADP
american_scientific_journal-7186	105	11	targeted	target	VERB
american_scientific_journal-7186	105	12	effects	effect	NOUN
american_scientific_journal-7186	105	13	1.6.1	1.6.1	NUM
american_scientific_journal-7186	105	14	.	.	PUNCT
american_scientific_journal-7186	106	1	mutation	mutation	NOUN
american_scientific_journal-7186	106	2	many	many	ADJ
american_scientific_journal-7186	106	3	studies	study	NOUN
american_scientific_journal-7186	106	4	reported	report	VERB
american_scientific_journal-7186	106	5	that	that	SCONJ
american_scientific_journal-7186	106	6	50	50	NUM
american_scientific_journal-7186	106	7	%	%	NOUN
american_scientific_journal-7186	106	8	of	of	ADP
american_scientific_journal-7186	106	9	cases	case	NOUN
american_scientific_journal-7186	106	10	of	of	ADP
american_scientific_journal-7186	106	11	crispr	crispr	NOUN
american_scientific_journal-7186	106	12	/	/	SYM
american_scientific_journal-7186	106	13	cas9	cas9	NOUN
american_scientific_journal-7186	106	14	caused	cause	VERB
american_scientific_journal-7186	106	15	single	single	ADJ
american_scientific_journal-7186	106	16	base	base	NOUN
american_scientific_journal-7186	106	17	mutations	mutation	NOUN
american_scientific_journal-7186	106	18	(	(	PUNCT
american_scientific_journal-7186	106	19	mostly	mostly	ADV
american_scientific_journal-7186	106	20	t	t	PROPN
american_scientific_journal-7186	106	21	and	and	CCONJ
american_scientific_journal-7186	106	22	a	a	PRON
american_scientific_journal-7186	106	23	)	)	PUNCT
american_scientific_journal-7186	106	24	.	.	PUNCT
american_scientific_journal-7186	107	1	rest	rest	NOUN
american_scientific_journal-7186	107	2	of	of	ADP
american_scientific_journal-7186	107	3	50	50	NUM
american_scientific_journal-7186	107	4	%	%	NOUN
american_scientific_journal-7186	107	5	causes	cause	VERB
american_scientific_journal-7186	107	6	the	the	DET
american_scientific_journal-7186	107	7	small	small	ADJ
american_scientific_journal-7186	107	8	deletions	deletion	NOUN
american_scientific_journal-7186	107	9	of	of	ADP
american_scientific_journal-7186	107	10	the	the	DET
american_scientific_journal-7186	107	11	nucleotides	nucleotide	NOUN
american_scientific_journal-7186	107	12	bases	basis	NOUN
american_scientific_journal-7186	107	13	(	(	PUNCT
american_scientific_journal-7186	107	14	1	1	NUM
american_scientific_journal-7186	107	15	-	-	PUNCT
american_scientific_journal-7186	107	16	50bp	50bp	NOUN
american_scientific_journal-7186	107	17	)	)	PUNCT
american_scientific_journal-7186	107	18	.	.	PUNCT
american_scientific_journal-7186	108	1	the	the	DET
american_scientific_journal-7186	108	2	substitution	substitution	NOUN
american_scientific_journal-7186	108	3	of	of	ADP
american_scientific_journal-7186	108	4	(	(	PUNCT
american_scientific_journal-7186	108	5	two	two	NUM
american_scientific_journal-7186	108	6	or	or	CCONJ
american_scientific_journal-7186	108	7	more	more	ADJ
american_scientific_journal-7186	108	8	)	)	PUNCT
american_scientific_journal-7186	108	9	bases	basis	NOUN
american_scientific_journal-7186	108	10	is	be	AUX
american_scientific_journal-7186	108	11	very	very	ADV
american_scientific_journal-7186	108	12	exceptional	exceptional	ADJ
american_scientific_journal-7186	108	13	.	.	PUNCT
american_scientific_journal-7186	109	1	in	in	ADP
american_scientific_journal-7186	109	2	filamentous	filamentous	ADJ
american_scientific_journal-7186	109	3	fungi	fungus	NOUN
american_scientific_journal-7186	109	4	,	,	PUNCT
american_scientific_journal-7186	109	5	mostly	mostly	ADV
american_scientific_journal-7186	109	6	used	use	VERB
american_scientific_journal-7186	109	7	system	system	NOUN
american_scientific_journal-7186	109	8	of	of	ADP
american_scientific_journal-7186	109	9	crispr	crispr	ADJ
american_scientific_journal-7186	109	10	/	/	SYM
american_scientific_journal-7186	109	11	cas9	cas9	NOUN
american_scientific_journal-7186	109	12	knockout	knockout	NOUN
american_scientific_journal-7186	109	13	only	only	ADV
american_scientific_journal-7186	109	14	use	use	VERB
american_scientific_journal-7186	109	15	a	a	DET
american_scientific_journal-7186	109	16	single	single	ADJ
american_scientific_journal-7186	109	17	gene	gene	NOUN
american_scientific_journal-7186	109	18	either	either	CCONJ
american_scientific_journal-7186	109	19	by	by	ADP
american_scientific_journal-7186	109	20	insertion	insertion	NOUN
american_scientific_journal-7186	109	21	of	of	ADP
american_scientific_journal-7186	109	22	single	single	ADJ
american_scientific_journal-7186	109	23	gene	gene	NOUN
american_scientific_journal-7186	109	24	or	or	CCONJ
american_scientific_journal-7186	109	25	by	by	ADP
american_scientific_journal-7186	109	26	deletion	deletion	NOUN
american_scientific_journal-7186	109	27	of	of	ADP
american_scientific_journal-7186	109	28	small	small	ADJ
american_scientific_journal-7186	109	29	fragment	fragment	NOUN
american_scientific_journal-7186	109	30	of	of	ADP
american_scientific_journal-7186	109	31	nucleotides	nucleotide	NOUN
american_scientific_journal-7186	109	32	.	.	PUNCT
american_scientific_journal-7186	110	1	if	if	SCONJ
american_scientific_journal-7186	110	2	in	in	ADP
american_scientific_journal-7186	110	3	a	a	DET
american_scientific_journal-7186	110	4	gene	gene	NOUN
american_scientific_journal-7186	110	5	more	more	ADJ
american_scientific_journal-7186	110	6	than	than	ADP
american_scientific_journal-7186	110	7	two	two	NUM
american_scientific_journal-7186	110	8	sites	site	NOUN
american_scientific_journal-7186	110	9	are	be	AUX
american_scientific_journal-7186	110	10	targeted	target	VERB
american_scientific_journal-7186	110	11	between	between	ADP
american_scientific_journal-7186	110	12	the	the	DET
american_scientific_journal-7186	110	13	targeted	target	VERB
american_scientific_journal-7186	110	14	sites	site	NOUN
american_scientific_journal-7186	110	15	deletion	deletion	NOUN
american_scientific_journal-7186	110	16	of	of	ADP
american_scientific_journal-7186	110	17	a	a	DET
american_scientific_journal-7186	110	18	several	several	ADJ
american_scientific_journal-7186	110	19	hundred	hundred	NUM
american_scientific_journal-7186	110	20	kbp	kbp	NOUN
american_scientific_journal-7186	110	21	gene	gene	NOUN
american_scientific_journal-7186	110	22	fragments	fragment	NOUN
american_scientific_journal-7186	110	23	may	may	AUX
american_scientific_journal-7186	110	24	take	take	VERB
american_scientific_journal-7186	110	25	place	place	NOUN
american_scientific_journal-7186	110	26	[	[	X
american_scientific_journal-7186	110	27	14	14	NUM
american_scientific_journal-7186	110	28	]	]	PUNCT
american_scientific_journal-7186	110	29	.	.	PUNCT
american_scientific_journal-7186	111	1	1.6.1	1.6.1	NUM
american_scientific_journal-7186	111	2	.	.	NOUN
american_scientific_journal-7186	111	3	off	off	ADP
american_scientific_journal-7186	111	4	target	target	NOUN
american_scientific_journal-7186	111	5	effects	effect	NOUN
american_scientific_journal-7186	111	6	the	the	DET
american_scientific_journal-7186	111	7	characteristics	characteristic	NOUN
american_scientific_journal-7186	111	8	of	of	ADP
american_scientific_journal-7186	111	9	system	system	NOUN
american_scientific_journal-7186	111	10	of	of	ADP
american_scientific_journal-7186	111	11	crispr	crispr	ADJ
american_scientific_journal-7186	111	12	/	/	SYM
american_scientific_journal-7186	111	13	cas9	cas9	NOUN
american_scientific_journal-7186	111	14	are	be	AUX
american_scientific_journal-7186	111	15	high	high	ADJ
american_scientific_journal-7186	111	16	efficiency	efficiency	NOUN
american_scientific_journal-7186	111	17	,	,	PUNCT
american_scientific_journal-7186	111	18	simple	simple	ADJ
american_scientific_journal-7186	111	19	procedure	procedure	NOUN
american_scientific_journal-7186	111	20	and	and	CCONJ
american_scientific_journal-7186	111	21	high	high	ADJ
american_scientific_journal-7186	111	22	accuracy	accuracy	NOUN
american_scientific_journal-7186	111	23	has	have	VERB
american_scientific_journal-7186	111	24	broad	broad	ADJ
american_scientific_journal-7186	111	25	application	application	NOUN
american_scientific_journal-7186	111	26	in	in	ADP
american_scientific_journal-7186	111	27	medical	medical	ADJ
american_scientific_journal-7186	111	28	and	and	CCONJ
american_scientific_journal-7186	111	29	biological	biological	ADJ
american_scientific_journal-7186	111	30	research	research	NOUN
american_scientific_journal-7186	111	31	.	.	PUNCT
american_scientific_journal-7186	112	1	the	the	DET
american_scientific_journal-7186	112	2	main	main	ADJ
american_scientific_journal-7186	112	3	concerns	concern	NOUN
american_scientific_journal-7186	112	4	are	be	AUX
american_scientific_journal-7186	112	5	the	the	DET
american_scientific_journal-7186	112	6	off	off	ADJ
american_scientific_journal-7186	112	7	sides	side	NOUN
american_scientific_journal-7186	112	8	effects	effect	NOUN
american_scientific_journal-7186	112	9	of	of	ADP
american_scientific_journal-7186	112	10	crispr	crispr	NOUN
american_scientific_journal-7186	112	11	/	/	SYM
american_scientific_journal-7186	112	12	cas9	cas9	NOUN
american_scientific_journal-7186	112	13	.	.	PUNCT
american_scientific_journal-7186	113	1	off	off	ADP
american_scientific_journal-7186	113	2	targeted	target	VERB
american_scientific_journal-7186	113	3	effect	effect	NOUN
american_scientific_journal-7186	113	4	of	of	ADP
american_scientific_journal-7186	113	5	system	system	NOUN
american_scientific_journal-7186	113	6	are	be	AUX
american_scientific_journal-7186	113	7	divided	divide	VERB
american_scientific_journal-7186	113	8	into	into	ADP
american_scientific_journal-7186	113	9	two	two	NUM
american_scientific_journal-7186	113	10	main	main	ADJ
american_scientific_journal-7186	113	11	categories	category	NOUN
american_scientific_journal-7186	113	12	.	.	PUNCT
american_scientific_journal-7186	114	1	firstly	firstly	ADV
american_scientific_journal-7186	114	2	,	,	PUNCT
american_scientific_journal-7186	114	3	more	more	ADJ
american_scientific_journal-7186	114	4	than	than	ADP
american_scientific_journal-7186	114	5	3	3	NUM
american_scientific_journal-7186	114	6	impatience	impatience	NOUN
american_scientific_journal-7186	114	7	mismatch	mismatch	NOUN
american_scientific_journal-7186	114	8	can	can	AUX
american_scientific_journal-7186	114	9	not	not	PART
american_scientific_journal-7186	114	10	distinguish	distinguish	VERB
american_scientific_journal-7186	114	11	by	by	ADP
american_scientific_journal-7186	114	12	crispr	crispr	NOUN
american_scientific_journal-7186	114	13	/	/	SYM
american_scientific_journal-7186	114	14	cas9	cas9	NOUN
american_scientific_journal-7186	114	15	at	at	ADP
american_scientific_journal-7186	114	16	site	site	NOUN
american_scientific_journal-7186	114	17	of	of	ADP
american_scientific_journal-7186	114	18	dna	dna	PROPN
american_scientific_journal-7186	114	19	.	.	PUNCT
american_scientific_journal-7186	115	1	secondly	secondly	ADV
american_scientific_journal-7186	115	2	,	,	PUNCT
american_scientific_journal-7186	115	3	high	high	ADJ
american_scientific_journal-7186	115	4	concentration	concentration	NOUN
american_scientific_journal-7186	115	5	of	of	ADP
american_scientific_journal-7186	115	6	crispr	crispr	NOUN
american_scientific_journal-7186	115	7	/	/	SYM
american_scientific_journal-7186	115	8	cas9	cas9	NOUN
american_scientific_journal-7186	115	9	the	the	DET
american_scientific_journal-7186	115	10	probability	probability	NOUN
american_scientific_journal-7186	115	11	of	of	ADP
american_scientific_journal-7186	115	12	effects	effect	NOUN
american_scientific_journal-7186	115	13	of	of	ADP
american_scientific_journal-7186	115	14	off	off	ADP
american_scientific_journal-7186	115	15	target	target	NOUN
american_scientific_journal-7186	115	16	increase	increase	NOUN
american_scientific_journal-7186	115	17	.	.	PUNCT
american_scientific_journal-7186	116	1	to	to	PART
american_scientific_journal-7186	116	2	overcome	overcome	VERB
american_scientific_journal-7186	116	3	these	these	DET
american_scientific_journal-7186	116	4	problems	problem	NOUN
american_scientific_journal-7186	116	5	scientists	scientist	NOUN
american_scientific_journal-7186	116	6	design	design	VERB
american_scientific_journal-7186	116	7	the	the	DET
american_scientific_journal-7186	116	8	dna	dna	NOUN
american_scientific_journal-7186	116	9	plasmid	plasmid	ADJ
american_scientific_journal-7186	116	10	which	which	PRON
american_scientific_journal-7186	116	11	after	after	ADP
american_scientific_journal-7186	116	12	editing	edit	VERB
american_scientific_journal-7186	116	13	of	of	ADP
american_scientific_journal-7186	116	14	genome	genome	NOUN
american_scientific_journal-7186	116	15	remove	remove	VERB
american_scientific_journal-7186	116	16	the	the	DET
american_scientific_journal-7186	116	17	gene	gene	NOUN
american_scientific_journal-7186	116	18	of	of	ADP
american_scientific_journal-7186	116	19	csa9	csa9	PROPN
american_scientific_journal-7186	116	20	inserted	insert	VERB
american_scientific_journal-7186	116	21	.	.	PUNCT
american_scientific_journal-7186	117	1	scientists	scientist	NOUN
american_scientific_journal-7186	117	2	in	in	ADP
american_scientific_journal-7186	117	3	[	[	X
american_scientific_journal-7186	117	4	15	15	NUM
american_scientific_journal-7186	117	5	]	]	PUNCT
american_scientific_journal-7186	117	6	developed	develop	VERB
american_scientific_journal-7186	117	7	a	a	DET
american_scientific_journal-7186	117	8	system	system	NOUN
american_scientific_journal-7186	117	9	of	of	ADP
american_scientific_journal-7186	117	10	crispr	crispr	NOUN
american_scientific_journal-7186	117	11	/	/	SYM
american_scientific_journal-7186	117	12	cas9	cas9	NOUN
american_scientific_journal-7186	117	13	in	in	ADP
american_scientific_journal-7186	117	14	which	which	PRON
american_scientific_journal-7186	117	15	sgrna	sgrna	NOUN
american_scientific_journal-7186	117	16	are	be	AUX
american_scientific_journal-7186	117	17	put	put	VERB
american_scientific_journal-7186	117	18	together	together	ADV
american_scientific_journal-7186	117	19	with	with	ADP
american_scientific_journal-7186	117	20	cas9	cas9	NOUN
american_scientific_journal-7186	117	21	for	for	ADP
american_scientific_journal-7186	117	22	the	the	DET
american_scientific_journal-7186	117	23	formation	formation	NOUN
american_scientific_journal-7186	117	24	of	of	ADP
american_scientific_journal-7186	117	25	a	a	DET
american_scientific_journal-7186	117	26	stable	stable	ADJ
american_scientific_journal-7186	117	27	rnp	rnp	PROPN
american_scientific_journal-7186	117	28	.	.	PUNCT
american_scientific_journal-7186	118	1	the	the	DET
american_scientific_journal-7186	118	2	transformation	transformation	NOUN
american_scientific_journal-7186	118	3	of	of	ADP
american_scientific_journal-7186	118	4	this	this	DET
american_scientific_journal-7186	118	5	complex	complex	NOUN
american_scientific_journal-7186	118	6	is	be	AUX
american_scientific_journal-7186	118	7	take	take	VERB
american_scientific_journal-7186	118	8	place	place	NOUN
american_scientific_journal-7186	118	9	by	by	ADP
american_scientific_journal-7186	118	10	electroporation	electroporation	NOUN
american_scientific_journal-7186	118	11	or	or	CCONJ
american_scientific_journal-7186	118	12	poly	poly	ADJ
american_scientific_journal-7186	118	13	ethylene	ethylene	NOUN
american_scientific_journal-7186	118	14	glycol	glycol	NOUN
american_scientific_journal-7186	118	15	(	(	PUNCT
american_scientific_journal-7186	118	16	peg	peg	NOUN
american_scientific_journal-7186	118	17	)	)	PUNCT
american_scientific_journal-7186	118	18	methods	method	NOUN
american_scientific_journal-7186	118	19	.	.	PUNCT
american_scientific_journal-7186	119	1	some	some	DET
american_scientific_journal-7186	119	2	methods	method	NOUN
american_scientific_journal-7186	119	3	which	which	PRON
american_scientific_journal-7186	119	4	are	be	AUX
american_scientific_journal-7186	119	5	based	base	VERB
american_scientific_journal-7186	119	6	on	on	ADP
american_scientific_journal-7186	119	7	sequencing	sequence	VERB
american_scientific_journal-7186	119	8	techniques	technique	NOUN
american_scientific_journal-7186	119	9	(	(	PUNCT
american_scientific_journal-7186	119	10	next	next	ADJ
american_scientific_journal-7186	119	11	-	-	PUNCT
american_scientific_journal-7186	119	12	generation	generation	NOUN
american_scientific_journal-7186	119	13	)	)	PUNCT
american_scientific_journal-7186	119	14	are	be	AUX
american_scientific_journal-7186	119	15	used	use	VERB
american_scientific_journal-7186	119	16	for	for	ADP
american_scientific_journal-7186	119	17	detection	detection	NOUN
american_scientific_journal-7186	119	18	of	of	ADP
american_scientific_journal-7186	119	19	off	off	ADP
american_scientific_journal-7186	119	20	targeted	target	VERB
american_scientific_journal-7186	119	21	sites	site	NOUN
american_scientific_journal-7186	119	22	.	.	PUNCT
american_scientific_journal-7186	120	1	these	these	DET
american_scientific_journal-7186	120	2	methods	method	NOUN
american_scientific_journal-7186	120	3	are	be	AUX
american_scientific_journal-7186	120	4	chip	chip	NOUN
american_scientific_journal-7186	120	5	-	-	PUNCT
american_scientific_journal-7186	120	6	seq	seq	NOUN
american_scientific_journal-7186	120	7	[	[	X
american_scientific_journal-7186	120	8	16	16	NUM
american_scientific_journal-7186	120	9	]	]	PUNCT
american_scientific_journal-7186	120	10	,	,	PUNCT
american_scientific_journal-7186	120	11	guide	guide	NOUN
american_scientific_journal-7186	120	12	-	-	PUNCT
american_scientific_journal-7186	120	13	seq	seq	NOUN
american_scientific_journal-7186	120	14	[	[	X
american_scientific_journal-7186	120	15	17	17	NUM
american_scientific_journal-7186	120	16	]	]	PUNCT
american_scientific_journal-7186	120	17	and	and	CCONJ
american_scientific_journal-7186	120	18	digenome	digenome	NOUN
american_scientific_journal-7186	120	19	-	-	PUNCT
american_scientific_journal-7186	120	20	seq	seq	NOUN
american_scientific_journal-7186	120	21	[	[	X
american_scientific_journal-7186	120	22	18	18	NUM
american_scientific_journal-7186	120	23	]	]	PUNCT
american_scientific_journal-7186	120	24	.	.	PUNCT
american_scientific_journal-7186	121	1	2	2	X
american_scientific_journal-7186	121	2	.	.	X
american_scientific_journal-7186	121	3	industrial	industrial	ADJ
american_scientific_journal-7186	121	4	applications	application	NOUN
american_scientific_journal-7186	121	5	to	to	PART
american_scientific_journal-7186	121	6	enhance	enhance	VERB
american_scientific_journal-7186	121	7	the	the	DET
american_scientific_journal-7186	121	8	production	production	NOUN
american_scientific_journal-7186	121	9	of	of	ADP
american_scientific_journal-7186	121	10	desirable	desirable	ADJ
american_scientific_journal-7186	121	11	products	product	NOUN
american_scientific_journal-7186	121	12	and	and	CCONJ
american_scientific_journal-7186	121	13	suppression	suppression	NOUN
american_scientific_journal-7186	121	14	of	of	ADP
american_scientific_journal-7186	121	15	secondary	secondary	ADJ
american_scientific_journal-7186	121	16	metabolites	metabolite	NOUN
american_scientific_journal-7186	121	17	filamentous	filamentous	ADJ
american_scientific_journal-7186	121	18	fungi	fungus	NOUN
american_scientific_journal-7186	121	19	produce	produce	VERB
american_scientific_journal-7186	121	20	a	a	DET
american_scientific_journal-7186	121	21	large	large	ADJ
american_scientific_journal-7186	121	22	number	number	NOUN
american_scientific_journal-7186	121	23	of	of	ADP
american_scientific_journal-7186	121	24	enzymes	enzyme	NOUN
american_scientific_journal-7186	121	25	which	which	PRON
american_scientific_journal-7186	121	26	play	play	VERB
american_scientific_journal-7186	121	27	a	a	DET
american_scientific_journal-7186	121	28	very	very	ADV
american_scientific_journal-7186	121	29	significant	significant	ADJ
american_scientific_journal-7186	121	30	role	role	NOUN
american_scientific_journal-7186	121	31	in	in	ADP
american_scientific_journal-7186	121	32	production	production	NOUN
american_scientific_journal-7186	121	33	of	of	ADP
american_scientific_journal-7186	121	34	american	american	ADJ
american_scientific_journal-7186	121	35	academic	academic	ADJ
american_scientific_journal-7186	121	36	scientific	scientific	ADJ
american_scientific_journal-7186	121	37	research	research	NOUN
american_scientific_journal-7186	121	38	journal	journal	NOUN
american_scientific_journal-7186	121	39	for	for	ADP
american_scientific_journal-7186	121	40	engineering	engineering	NOUN
american_scientific_journal-7186	121	41	,	,	PUNCT
american_scientific_journal-7186	121	42	technology	technology	NOUN
american_scientific_journal-7186	121	43	,	,	PUNCT
american_scientific_journal-7186	121	44	and	and	CCONJ
american_scientific_journal-7186	121	45	sciences(asrjets	sciences(asrjet	NOUN
american_scientific_journal-7186	121	46	)	)	PUNCT
american_scientific_journal-7186	121	47	(	(	PUNCT
american_scientific_journal-7186	121	48	2022)volume	2022)volume	NUM
american_scientific_journal-7186	121	49	85	85	NUM
american_scientific_journal-7186	121	50	,	,	PUNCT
american_scientific_journal-7186	121	51	no	no	DET
american_scientific_journal-7186	121	52	1	1	NUM
american_scientific_journal-7186	121	53	,	,	PUNCT
american_scientific_journal-7186	121	54	pp	pp	ADV
american_scientific_journal-7186	121	55	313	313	NUM
american_scientific_journal-7186	121	56	-	-	SYM
american_scientific_journal-7186	121	57	318	318	NUM
american_scientific_journal-7186	121	58	317	317	NUM
american_scientific_journal-7186	121	59	different	different	ADJ
american_scientific_journal-7186	121	60	industrial	industrial	ADJ
american_scientific_journal-7186	121	61	products	product	NOUN
american_scientific_journal-7186	121	62	like	like	ADP
american_scientific_journal-7186	121	63	food	food	NOUN
american_scientific_journal-7186	121	64	,	,	PUNCT
american_scientific_journal-7186	121	65	detergents	detergent	NOUN
american_scientific_journal-7186	121	66	,	,	PUNCT
american_scientific_journal-7186	121	67	textiles	textile	NOUN
american_scientific_journal-7186	121	68	and	and	CCONJ
american_scientific_journal-7186	121	69	feed	feed	NOUN
american_scientific_journal-7186	121	70	.	.	PUNCT
american_scientific_journal-7186	122	1	for	for	ADP
american_scientific_journal-7186	122	2	the	the	DET
american_scientific_journal-7186	122	3	production	production	NOUN
american_scientific_journal-7186	122	4	of	of	ADP
american_scientific_journal-7186	122	5	many	many	ADJ
american_scientific_journal-7186	122	6	fermented	ferment	VERB
american_scientific_journal-7186	122	7	food	food	NOUN
american_scientific_journal-7186	122	8	and	and	CCONJ
american_scientific_journal-7186	122	9	recombinant	recombinant	ADJ
american_scientific_journal-7186	122	10	protein	protein	NOUN
american_scientific_journal-7186	122	11	filamentous	filamentous	ADJ
american_scientific_journal-7186	122	12	fungi	fungus	NOUN
american_scientific_journal-7186	122	13	are	be	AUX
american_scientific_journal-7186	122	14	use	use	NOUN
american_scientific_journal-7186	122	15	.	.	PUNCT
american_scientific_journal-7186	123	1	filamentous	filamentous	ADJ
american_scientific_journal-7186	123	2	fungi	fungus	NOUN
american_scientific_journal-7186	123	3	are	be	AUX
american_scientific_journal-7186	123	4	also	also	ADV
american_scientific_journal-7186	123	5	a	a	DET
american_scientific_journal-7186	123	6	vital	vital	ADJ
american_scientific_journal-7186	123	7	host	host	NOUN
american_scientific_journal-7186	123	8	for	for	ADP
american_scientific_journal-7186	123	9	secondary	secondary	ADJ
american_scientific_journal-7186	123	10	metabolites	metabolite	NOUN
american_scientific_journal-7186	123	11	production	production	NOUN
american_scientific_journal-7186	123	12	in	in	ADP
american_scientific_journal-7186	123	13	many	many	ADJ
american_scientific_journal-7186	123	14	industries	industry	NOUN
american_scientific_journal-7186	123	15	.	.	PUNCT
american_scientific_journal-7186	124	1	for	for	ADP
american_scientific_journal-7186	124	2	example	example	NOUN
american_scientific_journal-7186	124	3	,	,	PUNCT
american_scientific_journal-7186	124	4	the	the	DET
american_scientific_journal-7186	124	5	genes	gene	NOUN
american_scientific_journal-7186	124	6	of	of	ADP
american_scientific_journal-7186	124	7	biotin	biotin	NOUN
american_scientific_journal-7186	124	8	and	and	CCONJ
american_scientific_journal-7186	124	9	four	four	NUM
american_scientific_journal-7186	124	10	subunits	subunit	NOUN
american_scientific_journal-7186	124	11	of	of	ADP
american_scientific_journal-7186	124	12	acetyl	acetyl	NOUN
american_scientific_journal-7186	124	13	-	-	PUNCT
american_scientific_journal-7186	124	14	coa	coa	NOUN
american_scientific_journal-7186	124	15	carboxylase	carboxylase	NOUN
american_scientific_journal-7186	124	16	(	(	PUNCT
american_scientific_journal-7186	124	17	acc	acc	PROPN
american_scientific_journal-7186	124	18	)	)	PUNCT
american_scientific_journal-7186	124	19	are	be	AUX
american_scientific_journal-7186	124	20	overexpress	overexpress	NOUN
american_scientific_journal-7186	124	21	in	in	ADP
american_scientific_journal-7186	124	22	photorhabdus	photorhabdus	PROPN
american_scientific_journal-7186	124	23	liminescens	liminescen	NOUN
american_scientific_journal-7186	124	24	.	.	PUNCT
american_scientific_journal-7186	125	1	the	the	DET
american_scientific_journal-7186	125	2	overexpression	overexpression	NOUN
american_scientific_journal-7186	125	3	of	of	ADP
american_scientific_journal-7186	125	4	these	these	DET
american_scientific_journal-7186	125	5	genes	gene	NOUN
american_scientific_journal-7186	125	6	in	in	ADP
american_scientific_journal-7186	125	7	the	the	DET
american_scientific_journal-7186	125	8	cells	cell	NOUN
american_scientific_journal-7186	125	9	of	of	ADP
american_scientific_journal-7186	125	10	microorganisms	microorganism	NOUN
american_scientific_journal-7186	125	11	makes	make	VERB
american_scientific_journal-7186	125	12	the	the	DET
american_scientific_journal-7186	125	13	metabolical	metabolical	ADJ
american_scientific_journal-7186	125	14	burden	burden	NOUN
american_scientific_journal-7186	125	15	.	.	PUNCT
american_scientific_journal-7186	126	1	to	to	PART
american_scientific_journal-7186	126	2	overcome	overcome	VERB
american_scientific_journal-7186	126	3	this	this	DET
american_scientific_journal-7186	126	4	problem	problem	NOUN
american_scientific_journal-7186	126	5	biotin	biotin	NOUN
american_scientific_journal-7186	126	6	is	be	AUX
american_scientific_journal-7186	126	7	required	require	VERB
american_scientific_journal-7186	126	8	as	as	ADP
american_scientific_journal-7186	126	9	a	a	DET
american_scientific_journal-7186	126	10	supplement	supplement	NOUN
american_scientific_journal-7186	126	11	in	in	ADP
american_scientific_journal-7186	126	12	the	the	DET
american_scientific_journal-7186	126	13	medium	medium	NOUN
american_scientific_journal-7186	126	14	at	at	ADP
american_scientific_journal-7186	126	15	industrial	industrial	ADJ
american_scientific_journal-7186	126	16	scale	scale	NOUN
american_scientific_journal-7186	126	17	.	.	PUNCT
american_scientific_journal-7186	127	1	so	so	ADV
american_scientific_journal-7186	127	2	genetic	genetic	ADJ
american_scientific_journal-7186	127	3	engineering	engineering	NOUN
american_scientific_journal-7186	127	4	is	be	AUX
american_scientific_journal-7186	127	5	requires	require	VERB
american_scientific_journal-7186	127	6	to	to	PART
american_scientific_journal-7186	127	7	increase	increase	VERB
american_scientific_journal-7186	127	8	the	the	DET
american_scientific_journal-7186	127	9	production	production	NOUN
american_scientific_journal-7186	127	10	of	of	ADP
american_scientific_journal-7186	127	11	these	these	DET
american_scientific_journal-7186	127	12	valuable	valuable	ADJ
american_scientific_journal-7186	127	13	metabolites	metabolite	NOUN
american_scientific_journal-7186	127	14	from	from	ADP
american_scientific_journal-7186	127	15	the	the	DET
american_scientific_journal-7186	127	16	filamentous	filamentous	ADJ
american_scientific_journal-7186	127	17	fungi	fungus	NOUN
american_scientific_journal-7186	127	18	.	.	PUNCT
american_scientific_journal-7186	128	1	to	to	PART
american_scientific_journal-7186	128	2	resolve	resolve	VERB
american_scientific_journal-7186	128	3	this	this	DET
american_scientific_journal-7186	128	4	problem	problem	NOUN
american_scientific_journal-7186	128	5	,	,	PUNCT
american_scientific_journal-7186	128	6	scientists	scientist	NOUN
american_scientific_journal-7186	128	7	have	have	AUX
american_scientific_journal-7186	128	8	established	establish	VERB
american_scientific_journal-7186	128	9	many	many	ADJ
american_scientific_journal-7186	128	10	new	new	ADJ
american_scientific_journal-7186	128	11	strategies	strategy	NOUN
american_scientific_journal-7186	128	12	to	to	PART
american_scientific_journal-7186	128	13	enhance	enhance	VERB
american_scientific_journal-7186	128	14	the	the	DET
american_scientific_journal-7186	128	15	production	production	NOUN
american_scientific_journal-7186	128	16	of	of	ADP
american_scientific_journal-7186	128	17	different	different	ADJ
american_scientific_journal-7186	128	18	products	product	NOUN
american_scientific_journal-7186	128	19	but	but	CCONJ
american_scientific_journal-7186	128	20	it	it	PRON
american_scientific_journal-7186	128	21	is	be	AUX
american_scientific_journal-7186	128	22	appropriate	appropriate	ADJ
american_scientific_journal-7186	128	23	to	to	AUX
american_scientific_journal-7186	128	24	limited	limit	VERB
american_scientific_journal-7186	128	25	no	no	PRON
american_scientific_journal-7186	128	26	of	of	ADP
american_scientific_journal-7186	128	27	filamentous	filamentous	ADJ
american_scientific_journal-7186	128	28	fungi	fungus	NOUN
american_scientific_journal-7186	128	29	.	.	PUNCT
american_scientific_journal-7186	129	1	the	the	DET
american_scientific_journal-7186	129	2	use	use	NOUN
american_scientific_journal-7186	129	3	of	of	ADP
american_scientific_journal-7186	129	4	genome	genome	NOUN
american_scientific_journal-7186	129	5	editing	editing	NOUN
american_scientific_journal-7186	129	6	method	method	NOUN
american_scientific_journal-7186	129	7	of	of	ADP
american_scientific_journal-7186	129	8	crispr	crispr	NOUN
american_scientific_journal-7186	129	9	/	/	SYM
american_scientific_journal-7186	129	10	cas9	cas9	NOUN
american_scientific_journal-7186	129	11	in	in	ADP
american_scientific_journal-7186	129	12	many	many	ADJ
american_scientific_journal-7186	129	13	fungi	fungus	NOUN
american_scientific_journal-7186	129	14	which	which	PRON
american_scientific_journal-7186	129	15	are	be	AUX
american_scientific_journal-7186	129	16	important	important	ADJ
american_scientific_journal-7186	129	17	at	at	ADP
american_scientific_journal-7186	129	18	industrial	industrial	ADJ
american_scientific_journal-7186	129	19	scale	scale	NOUN
american_scientific_journal-7186	129	20	significantly	significantly	ADV
american_scientific_journal-7186	129	21	enhance	enhance	VERB
american_scientific_journal-7186	129	22	the	the	DET
american_scientific_journal-7186	129	23	production	production	NOUN
american_scientific_journal-7186	129	24	capability	capability	NOUN
american_scientific_journal-7186	129	25	of	of	ADP
american_scientific_journal-7186	129	26	these	these	DET
american_scientific_journal-7186	129	27	filamentous	filamentous	ADJ
american_scientific_journal-7186	129	28	fungi	fungus	NOUN
american_scientific_journal-7186	129	29	.	.	PUNCT
american_scientific_journal-7186	130	1	aspergillus	aspergillus	NOUN
american_scientific_journal-7186	130	2	oryzae	oryzae	NOUN
american_scientific_journal-7186	130	3	is	be	AUX
american_scientific_journal-7186	130	4	a	a	DET
american_scientific_journal-7186	130	5	filamentous	filamentous	ADJ
american_scientific_journal-7186	130	6	fungi	fungus	NOUN
american_scientific_journal-7186	130	7	which	which	PRON
american_scientific_journal-7186	130	8	is	be	AUX
american_scientific_journal-7186	130	9	used	use	VERB
american_scientific_journal-7186	130	10	in	in	ADP
american_scientific_journal-7186	130	11	industry	industry	NOUN
american_scientific_journal-7186	130	12	for	for	ADP
american_scientific_journal-7186	130	13	the	the	DET
american_scientific_journal-7186	130	14	production	production	NOUN
american_scientific_journal-7186	130	15	of	of	ADP
american_scientific_journal-7186	130	16	cellulose	cellulose	NOUN
american_scientific_journal-7186	130	17	.	.	PUNCT
american_scientific_journal-7186	131	1	in	in	ADP
american_scientific_journal-7186	131	2	japan	japan	PROPN
american_scientific_journal-7186	131	3	it	it	PRON
american_scientific_journal-7186	131	4	is	be	AUX
american_scientific_journal-7186	131	5	a	a	DET
american_scientific_journal-7186	131	6	very	very	ADV
american_scientific_journal-7186	131	7	significant	significant	ADJ
american_scientific_journal-7186	131	8	fungus	fungus	NOUN
american_scientific_journal-7186	131	9	for	for	ADP
american_scientific_journal-7186	131	10	conventional	conventional	ADJ
american_scientific_journal-7186	131	11	fermentation	fermentation	NOUN
american_scientific_journal-7186	131	12	for	for	ADP
american_scientific_journal-7186	131	13	production	production	NOUN
american_scientific_journal-7186	131	14	of	of	ADP
american_scientific_journal-7186	131	15	many	many	ADJ
american_scientific_journal-7186	131	16	proteins	protein	NOUN
american_scientific_journal-7186	131	17	as	as	ADV
american_scientific_journal-7186	131	18	well	well	ADV
american_scientific_journal-7186	131	19	as	as	ADP
american_scientific_journal-7186	131	20	enzymes	enzyme	NOUN
american_scientific_journal-7186	131	21	.	.	PUNCT
american_scientific_journal-7186	132	1	for	for	ADP
american_scientific_journal-7186	132	2	increasing	increase	VERB
american_scientific_journal-7186	132	3	the	the	DET
american_scientific_journal-7186	132	4	production	production	NOUN
american_scientific_journal-7186	132	5	of	of	ADP
american_scientific_journal-7186	132	6	these	these	DET
american_scientific_journal-7186	132	7	compounds	compound	NOUN
american_scientific_journal-7186	132	8	and	and	CCONJ
american_scientific_journal-7186	132	9	enzymes	enzyme	NOUN
american_scientific_journal-7186	132	10	it	it	PRON
american_scientific_journal-7186	132	11	is	be	AUX
american_scientific_journal-7186	132	12	essential	essential	ADJ
american_scientific_journal-7186	132	13	to	to	PART
american_scientific_journal-7186	132	14	modify	modify	VERB
american_scientific_journal-7186	132	15	the	the	DET
american_scientific_journal-7186	132	16	fungus	fungus	NOUN
american_scientific_journal-7186	132	17	by	by	ADP
american_scientific_journal-7186	132	18	genetic	genetic	ADJ
american_scientific_journal-7186	132	19	engineering	engineering	NOUN
american_scientific_journal-7186	132	20	.	.	PUNCT
american_scientific_journal-7186	133	1	scientists	scientist	NOUN
american_scientific_journal-7186	133	2	in	in	ADP
american_scientific_journal-7186	133	3	[	[	X
american_scientific_journal-7186	133	4	19	19	NUM
american_scientific_journal-7186	133	5	]	]	PUNCT
american_scientific_journal-7186	133	6	developed	develop	VERB
american_scientific_journal-7186	133	7	a	a	DET
american_scientific_journal-7186	133	8	method	method	NOUN
american_scientific_journal-7186	133	9	of	of	ADP
american_scientific_journal-7186	133	10	crispr	crispr	NOUN
american_scientific_journal-7186	133	11	for	for	ADP
american_scientific_journal-7186	133	12	genetically	genetically	ADV
american_scientific_journal-7186	133	13	modify	modify	VERB
american_scientific_journal-7186	133	14	the	the	DET
american_scientific_journal-7186	133	15	aspergillus	aspergillus	ADJ
american_scientific_journal-7186	133	16	oryzae	oryzae	NOUN
american_scientific_journal-7186	133	17	.	.	PUNCT
american_scientific_journal-7186	134	1	they	they	PRON
american_scientific_journal-7186	134	2	modify	modify	VERB
american_scientific_journal-7186	134	3	the	the	DET
american_scientific_journal-7186	134	4	fungus	fungus	NOUN
american_scientific_journal-7186	134	5	by	by	ADP
american_scientific_journal-7186	134	6	using	use	VERB
american_scientific_journal-7186	134	7	process	process	NOUN
american_scientific_journal-7186	134	8	of	of	ADP
american_scientific_journal-7186	134	9	mutagenesis	mutagenesis	NOUN
american_scientific_journal-7186	134	10	which	which	PRON
american_scientific_journal-7186	134	11	have	have	VERB
american_scientific_journal-7186	134	12	very	very	ADV
american_scientific_journal-7186	134	13	low	low	ADJ
american_scientific_journal-7186	134	14	efficiency	efficiency	NOUN
american_scientific_journal-7186	134	15	.	.	PUNCT
american_scientific_journal-7186	135	1	to	to	PART
american_scientific_journal-7186	135	2	improve	improve	VERB
american_scientific_journal-7186	135	3	the	the	DET
american_scientific_journal-7186	135	4	effectiveness	effectiveness	NOUN
american_scientific_journal-7186	135	5	of	of	ADP
american_scientific_journal-7186	135	6	genome	genome	NOUN
american_scientific_journal-7186	135	7	editing	editing	NOUN
american_scientific_journal-7186	135	8	method	method	NOUN
american_scientific_journal-7186	135	9	of	of	ADP
american_scientific_journal-7186	135	10	crispr	crispr	NOUN
american_scientific_journal-7186	135	11	/	/	SYM
american_scientific_journal-7186	135	12	cas9	cas9	NOUN
american_scientific_journal-7186	135	13	they	they	PRON
american_scientific_journal-7186	135	14	use	use	VERB
american_scientific_journal-7186	135	15	a	a	DET
american_scientific_journal-7186	135	16	plasmid	plasmid	NOUN
american_scientific_journal-7186	135	17	carrying	carry	VERB
american_scientific_journal-7186	135	18	ama1	ama1	PROPN
american_scientific_journal-7186	135	19	.	.	PUNCT
american_scientific_journal-7186	136	1	it	it	PRON
american_scientific_journal-7186	136	2	is	be	AUX
american_scientific_journal-7186	136	3	a	a	DET
american_scientific_journal-7186	136	4	selfreplicating	selfreplicate	VERB
american_scientific_journal-7186	136	5	nucleotides	nucleotide	NOUN
american_scientific_journal-7186	136	6	sequence	sequence	NOUN
american_scientific_journal-7186	136	7	which	which	PRON
american_scientific_journal-7186	136	8	enhances	enhance	VERB
american_scientific_journal-7186	136	9	the	the	DET
american_scientific_journal-7186	136	10	efficiency	efficiency	NOUN
american_scientific_journal-7186	136	11	of	of	ADP
american_scientific_journal-7186	136	12	mutation	mutation	NOUN
american_scientific_journal-7186	136	13	in	in	ADP
american_scientific_journal-7186	136	14	wild	wild	ADJ
american_scientific_journal-7186	136	15	strain	strain	NOUN
american_scientific_journal-7186	136	16	of	of	ADP
american_scientific_journal-7186	136	17	aspergillus	aspergillus	ADJ
american_scientific_journal-7186	136	18	oryzae	oryzae	NOUN
american_scientific_journal-7186	136	19	to	to	ADP
american_scientific_journal-7186	136	20	60	60	NUM
american_scientific_journal-7186	136	21	-	-	SYM
american_scientific_journal-7186	136	22	100	100	NUM
american_scientific_journal-7186	136	23	%	%	NOUN
american_scientific_journal-7186	136	24	.	.	PUNCT
american_scientific_journal-7186	137	1	the	the	DET
american_scientific_journal-7186	137	2	multiple	multiple	ADJ
american_scientific_journal-7186	137	3	copies	copy	NOUN
american_scientific_journal-7186	137	4	of	of	ADP
american_scientific_journal-7186	137	5	ama1	ama1	PROPN
american_scientific_journal-7186	137	6	plasmid	plasmid	NOUN
american_scientific_journal-7186	137	7	was	be	AUX
american_scientific_journal-7186	137	8	existing	exist	VERB
american_scientific_journal-7186	137	9	in	in	ADP
american_scientific_journal-7186	137	10	fungal	fungal	ADJ
american_scientific_journal-7186	137	11	stain	stain	NOUN
american_scientific_journal-7186	137	12	.	.	PUNCT
american_scientific_journal-7186	138	1	they	they	PRON
american_scientific_journal-7186	138	2	enhance	enhance	VERB
american_scientific_journal-7186	138	3	the	the	DET
american_scientific_journal-7186	138	4	expression	expression	NOUN
american_scientific_journal-7186	138	5	level	level	NOUN
american_scientific_journal-7186	138	6	of	of	ADP
american_scientific_journal-7186	138	7	sgrna	sgrna	NOUN
american_scientific_journal-7186	138	8	and	and	CCONJ
american_scientific_journal-7186	138	9	cas9	cas9	NOUN
american_scientific_journal-7186	138	10	and	and	CCONJ
american_scientific_journal-7186	138	11	eventually	eventually	ADV
american_scientific_journal-7186	138	12	escalate	escalate	VERB
american_scientific_journal-7186	138	13	efficiency	efficiency	NOUN
american_scientific_journal-7186	138	14	of	of	ADP
american_scientific_journal-7186	138	15	mutation	mutation	NOUN
american_scientific_journal-7186	138	16	of	of	ADP
american_scientific_journal-7186	138	17	aspergillus	aspergillus	ADJ
american_scientific_journal-7186	138	18	oryzae	oryzae	NOUN
american_scientific_journal-7186	138	19	[	[	X
american_scientific_journal-7186	138	20	19	19	NUM
american_scientific_journal-7186	138	21	]	]	PUNCT
american_scientific_journal-7186	138	22	.	.	PUNCT
american_scientific_journal-7186	139	1	3	3	X
american_scientific_journal-7186	139	2	.	.	X
american_scientific_journal-7186	139	3	conclusion	conclusion	NOUN
american_scientific_journal-7186	139	4	filamentous	filamentous	ADJ
american_scientific_journal-7186	139	5	fungi	fungus	NOUN
american_scientific_journal-7186	139	6	played	play	VERB
american_scientific_journal-7186	139	7	very	very	ADV
american_scientific_journal-7186	139	8	significant	significant	ADJ
american_scientific_journal-7186	139	9	role	role	NOUN
american_scientific_journal-7186	139	10	in	in	ADP
american_scientific_journal-7186	139	11	development	development	NOUN
american_scientific_journal-7186	139	12	of	of	ADP
american_scientific_journal-7186	139	13	drugs	drug	NOUN
american_scientific_journal-7186	139	14	,	,	PUNCT
american_scientific_journal-7186	139	15	biodegradation	biodegradation	NOUN
american_scientific_journal-7186	139	16	of	of	ADP
american_scientific_journal-7186	139	17	different	different	ADJ
american_scientific_journal-7186	139	18	substances	substance	NOUN
american_scientific_journal-7186	139	19	,	,	PUNCT
american_scientific_journal-7186	139	20	agriculture	agriculture	NOUN
american_scientific_journal-7186	139	21	and	and	CCONJ
american_scientific_journal-7186	139	22	production	production	NOUN
american_scientific_journal-7186	139	23	at	at	ADP
american_scientific_journal-7186	139	24	industrial	industrial	ADJ
american_scientific_journal-7186	139	25	scale	scale	NOUN
american_scientific_journal-7186	139	26	.	.	PUNCT
american_scientific_journal-7186	140	1	as	as	ADP
american_scientific_journal-7186	140	2	technique	technique	NOUN
american_scientific_journal-7186	140	3	for	for	ADP
american_scientific_journal-7186	140	4	the	the	DET
american_scientific_journal-7186	140	5	sequencing	sequencing	NOUN
american_scientific_journal-7186	140	6	of	of	ADP
american_scientific_journal-7186	140	7	genome	genome	NOUN
american_scientific_journal-7186	140	8	improve	improve	VERB
american_scientific_journal-7186	140	9	and	and	CCONJ
american_scientific_journal-7186	140	10	decrease	decrease	VERB
american_scientific_journal-7186	140	11	the	the	DET
american_scientific_journal-7186	140	12	cost	cost	NOUN
american_scientific_journal-7186	140	13	.	.	PUNCT
american_scientific_journal-7186	141	1	editing	edit	VERB
american_scientific_journal-7186	141	2	of	of	ADP
american_scientific_journal-7186	141	3	the	the	DET
american_scientific_journal-7186	141	4	genome	genome	NOUN
american_scientific_journal-7186	141	5	by	by	ADP
american_scientific_journal-7186	141	6	using	use	VERB
american_scientific_journal-7186	141	7	crispr	crispr	ADJ
american_scientific_journal-7186	141	8	/	/	SYM
american_scientific_journal-7186	141	9	cas9	cas9	NOUN
american_scientific_journal-7186	141	10	system	system	NOUN
american_scientific_journal-7186	141	11	enables	enable	VERB
american_scientific_journal-7186	141	12	the	the	DET
american_scientific_journal-7186	141	13	manipulation	manipulation	NOUN
american_scientific_journal-7186	141	14	of	of	ADP
american_scientific_journal-7186	141	15	the	the	DET
american_scientific_journal-7186	141	16	genome	genome	NOUN
american_scientific_journal-7186	141	17	.	.	PUNCT
american_scientific_journal-7186	142	1	the	the	DET
american_scientific_journal-7186	142	2	system	system	NOUN
american_scientific_journal-7186	142	3	of	of	ADP
american_scientific_journal-7186	142	4	crispr	crispr	ADJ
american_scientific_journal-7186	142	5	/	/	SYM
american_scientific_journal-7186	142	6	cas9	cas9	NOUN
american_scientific_journal-7186	142	7	technique	technique	NOUN
american_scientific_journal-7186	142	8	could	could	AUX
american_scientific_journal-7186	142	9	significantly	significantly	ADV
american_scientific_journal-7186	142	10	help	help	VERB
american_scientific_journal-7186	142	11	in	in	ADP
american_scientific_journal-7186	142	12	utilization	utilization	NOUN
american_scientific_journal-7186	142	13	of	of	ADP
american_scientific_journal-7186	142	14	filamentous	filamentous	ADJ
american_scientific_journal-7186	142	15	fungi	fungus	NOUN
american_scientific_journal-7186	142	16	as	as	ADP
american_scientific_journal-7186	142	17	biological	biological	ADJ
american_scientific_journal-7186	142	18	factories	factory	NOUN
american_scientific_journal-7186	142	19	.	.	PUNCT
american_scientific_journal-7186	143	1	for	for	ADP
american_scientific_journal-7186	143	2	medicine	medicine	NOUN
american_scientific_journal-7186	143	3	industries	industry	NOUN
american_scientific_journal-7186	143	4	manipulation	manipulation	NOUN
american_scientific_journal-7186	143	5	of	of	ADP
american_scientific_journal-7186	143	6	genes	gene	NOUN
american_scientific_journal-7186	143	7	of	of	ADP
american_scientific_journal-7186	143	8	different	different	ADJ
american_scientific_journal-7186	143	9	secondary	secondary	ADJ
american_scientific_journal-7186	143	10	metabolites	metabolite	NOUN
american_scientific_journal-7186	143	11	in	in	ADP
american_scientific_journal-7186	143	12	genome	genome	NOUN
american_scientific_journal-7186	143	13	of	of	ADP
american_scientific_journal-7186	143	14	filamentous	filamentous	ADJ
american_scientific_journal-7186	143	15	fungi	fungus	NOUN
american_scientific_journal-7186	143	16	is	be	AUX
american_scientific_journal-7186	143	17	used	use	VERB
american_scientific_journal-7186	143	18	for	for	ADP
american_scientific_journal-7186	143	19	production	production	NOUN
american_scientific_journal-7186	143	20	of	of	ADP
american_scientific_journal-7186	143	21	biological	biological	ADJ
american_scientific_journal-7186	143	22	active	active	ADJ
american_scientific_journal-7186	143	23	products	product	NOUN
american_scientific_journal-7186	143	24	.	.	PUNCT
american_scientific_journal-7186	144	1	the	the	DET
american_scientific_journal-7186	144	2	technology	technology	NOUN
american_scientific_journal-7186	144	3	has	have	VERB
american_scientific_journal-7186	144	4	some	some	DET
american_scientific_journal-7186	144	5	lacks	lack	NOUN
american_scientific_journal-7186	144	6	like	like	INTJ
american_scientific_journal-7186	144	7	off	off	ADP
american_scientific_journal-7186	144	8	sites	site	NOUN
american_scientific_journal-7186	144	9	an	an	DET
american_scientific_journal-7186	144	10	effect	effect	NOUN
american_scientific_journal-7186	144	11	so	so	SCONJ
american_scientific_journal-7186	144	12	there	there	PRON
american_scientific_journal-7186	144	13	is	be	VERB
american_scientific_journal-7186	144	14	still	still	ADV
american_scientific_journal-7186	144	15	requirement	requirement	ADJ
american_scientific_journal-7186	144	16	to	to	PART
american_scientific_journal-7186	144	17	improve	improve	VERB
american_scientific_journal-7186	144	18	the	the	DET
american_scientific_journal-7186	144	19	efficiency	efficiency	NOUN
american_scientific_journal-7186	144	20	of	of	ADP
american_scientific_journal-7186	144	21	editing	edit	VERB
american_scientific_journal-7186	144	22	.	.	PUNCT
american_scientific_journal-7186	145	1	after	after	SCONJ
american_scientific_journal-7186	145	2	faulty	faulty	ADJ
american_scientific_journal-7186	145	3	gene	gene	NOUN
american_scientific_journal-7186	145	4	repair	repair	VERB
american_scientific_journal-7186	145	5	the	the	DET
american_scientific_journal-7186	145	6	function	function	NOUN
american_scientific_journal-7186	145	7	of	of	ADP
american_scientific_journal-7186	145	8	genome	genome	NOUN
american_scientific_journal-7186	145	9	editing	editing	NOUN
american_scientific_journal-7186	145	10	will	will	AUX
american_scientific_journal-7186	145	11	continue	continue	VERB
american_scientific_journal-7186	145	12	which	which	PRON
american_scientific_journal-7186	145	13	increase	increase	VERB
american_scientific_journal-7186	145	14	the	the	DET
american_scientific_journal-7186	145	15	risk	risk	NOUN
american_scientific_journal-7186	145	16	of	of	ADP
american_scientific_journal-7186	145	17	off	off	ADJ
american_scientific_journal-7186	145	18	sites	site	NOUN
american_scientific_journal-7186	145	19	effects	effect	NOUN
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american_scientific_journal-7186	161	4	.	.	PUNCT
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american_scientific_journal-7186	162	28	-	-	PUNCT
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american_scientific_journal-7186	164	5	-	-	SYM
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american_scientific_journal-7186	166	2	5	5	NUM
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american_scientific_journal-7186	167	10	-	-	SYM
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american_scientific_journal-7186	170	4	,	,	PUNCT
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american_scientific_journal-7186	170	31	/	/	SYM
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american_scientific_journal-7186	180	10	,	,	PUNCT
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american_scientific_journal-7186	180	19	major	major	ADJ
american_scientific_journal-7186	180	20	facilitator	facilitator	NOUN
american_scientific_journal-7186	180	21	superfamily	superfamily	NOUN
american_scientific_journal-7186	180	22	transporter	transporter	NOUN
american_scientific_journal-7186	180	23	in	in	ADP
american_scientific_journal-7186	180	24	shiraia	shiraia	PROPN
american_scientific_journal-7186	180	25	bambusicola	bambusicola	PROPN
american_scientific_journal-7186	180	26	.	.	PUNCT
american_scientific_journal-7186	181	1	res	re	NOUN
american_scientific_journal-7186	181	2	.	.	PUNCT
american_scientific_journal-7186	181	3	microbiol	microbiol	PROPN
american_scientific_journal-7186	181	4	.	.	PUNCT
american_scientific_journal-7186	182	1	168(7	168(7	NUM
american_scientific_journal-7186	182	2	)	)	PUNCT
american_scientific_journal-7186	182	3	,	,	PUNCT
american_scientific_journal-7186	182	4	664–672	664–672	NUM
american_scientific_journal-7186	182	5	(	(	PUNCT
american_scientific_journal-7186	182	6	2017	2017	NUM
american_scientific_journal-7186	182	7	)	)	PUNCT
american_scientific_journal-7186	182	8	.	.	PUNCT
american_scientific_journal-7186	183	1	[	[	X
american_scientific_journal-7186	183	2	9	9	NUM
american_scientific_journal-7186	183	3	]	]	PUNCT
american_scientific_journal-7186	183	4	.	.	PUNCT
american_scientific_journal-7186	184	1	gao	gao	PROPN
american_scientific_journal-7186	184	2	,	,	PUNCT
american_scientific_journal-7186	184	3	y.	y.	PROPN
american_scientific_journal-7186	184	4	&	&	CCONJ
american_scientific_journal-7186	184	5	zhao	zhao	PROPN
american_scientific_journal-7186	184	6	,	,	PUNCT
american_scientific_journal-7186	184	7	y.	y.	PROPN
american_scientific_journal-7186	184	8	self	self	NOUN
american_scientific_journal-7186	184	9	-	-	PUNCT
american_scientific_journal-7186	184	10	processing	processing	NOUN
american_scientific_journal-7186	184	11	of	of	ADP
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american_scientific_journal-7186	184	13	-	-	PUNCT
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american_scientific_journal-7186	184	15	rnas	rna	NOUN
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american_scientific_journal-7186	184	18	rnas	rna	NOUN
american_scientific_journal-7186	184	19	in	in	ADP
american_scientific_journal-7186	184	20	vitro	vitro	X
american_scientific_journal-7186	184	21	and	and	CCONJ
american_scientific_journal-7186	184	22	in	in	ADP
american_scientific_journal-7186	184	23	vivo	vivo	NOUN
american_scientific_journal-7186	184	24	for	for	ADP
american_scientific_journal-7186	184	25	crispr	crispr	NOUN
american_scientific_journal-7186	184	26	-	-	PUNCT
american_scientific_journal-7186	184	27	mediated	mediate	VERB
american_scientific_journal-7186	184	28	genome	genome	NOUN
american_scientific_journal-7186	184	29	editing	editing	NOUN
american_scientific_journal-7186	184	30	.	.	PUNCT
american_scientific_journal-7186	185	1	j	j	PROPN
american_scientific_journal-7186	185	2	integr	integr	PROPN
american_scientific_journal-7186	185	3	plant	plant	PROPN
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american_scientific_journal-7186	185	5	.	.	PUNCT
american_scientific_journal-7186	186	1	56(4	56(4	NUM
american_scientific_journal-7186	186	2	)	)	PUNCT
american_scientific_journal-7186	186	3	,	,	PUNCT
american_scientific_journal-7186	186	4	343–349	343–349	NUM
american_scientific_journal-7186	186	5	.	.	PUNCT
american_scientific_journal-7186	187	1	(	(	PUNCT
american_scientific_journal-7186	187	2	2014	2014	NUM
american_scientific_journal-7186	187	3	)	)	PUNCT
american_scientific_journal-7186	187	4	.	.	PUNCT
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american_scientific_journal-7186	188	2	10	10	NUM
american_scientific_journal-7186	188	3	]	]	PUNCT
american_scientific_journal-7186	188	4	.	.	PUNCT
american_scientific_journal-7186	189	1	liang	liang	PROPN
american_scientific_journal-7186	189	2	,	,	PUNCT
american_scientific_journal-7186	189	3	y.	y.	PROPN
american_scientific_journal-7186	189	4	,	,	PUNCT
american_scientific_journal-7186	189	5	han	han	PROPN
american_scientific_journal-7186	189	6	,	,	PUNCT
american_scientific_journal-7186	189	7	y.	y.	PROPN
american_scientific_journal-7186	189	8	,	,	PUNCT
american_scientific_journal-7186	189	9	wang	wang	PROPN
american_scientific_journal-7186	189	10	,	,	PUNCT
american_scientific_journal-7186	189	11	c.	c.	PROPN
american_scientific_journal-7186	189	12	,	,	PUNCT
american_scientific_journal-7186	189	13	jiang	jiang	PROPN
american_scientific_journal-7186	189	14	,	,	PUNCT
american_scientific_journal-7186	189	15	c.	c.	PROPN
american_scientific_journal-7186	189	16	&	&	CCONJ
american_scientific_journal-7186	189	17	xu	xu	PROPN
american_scientific_journal-7186	189	18	,	,	PUNCT
american_scientific_journal-7186	189	19	j.r	j.r	PROPN
american_scientific_journal-7186	189	20	.	.	PROPN
american_scientific_journal-7186	189	21	targeted	target	VERB
american_scientific_journal-7186	189	22	deletion	deletion	NOUN
american_scientific_journal-7186	189	23	of	of	ADP
american_scientific_journal-7186	189	24	the	the	DET
american_scientific_journal-7186	189	25	usta	usta	NOUN
american_scientific_journal-7186	189	26	and	and	CCONJ
american_scientific_journal-7186	189	27	uvslt2	uvslt2	ADJ
american_scientific_journal-7186	189	28	genes	gene	NOUN
american_scientific_journal-7186	189	29	efficiently	efficiently	ADV
american_scientific_journal-7186	189	30	in	in	ADP
american_scientific_journal-7186	189	31	ustilaginoidea	ustilaginoidea	NOUN
american_scientific_journal-7186	189	32	virens	viren	NOUN
american_scientific_journal-7186	189	33	with	with	ADP
american_scientific_journal-7186	189	34	the	the	DET
american_scientific_journal-7186	189	35	crispr	crispr	ADJ
american_scientific_journal-7186	189	36	-	-	PUNCT
american_scientific_journal-7186	189	37	cas9	cas9	NOUN
american_scientific_journal-7186	189	38	system	system	NOUN
american_scientific_journal-7186	189	39	.	.	PUNCT
american_scientific_journal-7186	190	1	front	front	ADJ
american_scientific_journal-7186	190	2	plant	plant	NOUN
american_scientific_journal-7186	190	3	sci	sci	PROPN
american_scientific_journal-7186	190	4	.	.	PUNCT
american_scientific_journal-7186	191	1	9(89	9(89	NUM
american_scientific_journal-7186	191	2	)	)	PUNCT
american_scientific_journal-7186	191	3	,	,	PUNCT
american_scientific_journal-7186	191	4	699(2018	699(2018	NUM
american_scientific_journal-7186	191	5	)	)	PUNCT
american_scientific_journal-7186	191	6	.	.	PUNCT
american_scientific_journal-7186	192	1	[	[	X
american_scientific_journal-7186	192	2	11	11	NUM
american_scientific_journal-7186	192	3	]	]	PUNCT
american_scientific_journal-7186	192	4	.	.	PUNCT
american_scientific_journal-7186	193	1	zheng	zheng	PROPN
american_scientific_journal-7186	193	2	,	,	PUNCT
american_scientific_journal-7186	193	3	x.	x.	PROPN
american_scientific_journal-7186	193	4	,	,	PUNCT
american_scientific_journal-7186	193	5	zheng	zheng	PROPN
american_scientific_journal-7186	193	6	,	,	PUNCT
american_scientific_journal-7186	193	7	p.	p.	PROPN
american_scientific_journal-7186	193	8	,	,	PUNCT
american_scientific_journal-7186	193	9	zhang	zhang	PROPN
american_scientific_journal-7186	193	10	,	,	PUNCT
american_scientific_journal-7186	193	11	k.	k.	PROPN
american_scientific_journal-7186	193	12	,	,	PUNCT
american_scientific_journal-7186	193	13	cairns	cairns	PROPN
american_scientific_journal-7186	193	14	,	,	PUNCT
american_scientific_journal-7186	193	15	t.	t.	PROPN
american_scientific_journal-7186	193	16	c.	c.	PROPN
american_scientific_journal-7186	193	17	,	,	PUNCT
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american_scientific_journal-7186	193	19	,	,	PUNCT
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american_scientific_journal-7186	193	21	,	,	PUNCT
american_scientific_journal-7186	193	22	sun	sun	PROPN
american_scientific_journal-7186	193	23	,	,	PUNCT
american_scientific_journal-7186	193	24	j.	j.	PROPN
american_scientific_journal-7186	193	25	,	,	PUNCT
american_scientific_journal-7186	193	26	&	&	CCONJ
american_scientific_journal-7186	193	27	ma	ma	PROPN
american_scientific_journal-7186	193	28	,	,	PUNCT
american_scientific_journal-7186	193	29	y.	y.	PROPN
american_scientific_journal-7186	193	30	5s	5s	PROPN
american_scientific_journal-7186	193	31	rrna	rrna	NOUN
american_scientific_journal-7186	193	32	promoter	promoter	NOUN
american_scientific_journal-7186	193	33	for	for	ADP
american_scientific_journal-7186	193	34	guide	guide	NOUN
american_scientific_journal-7186	193	35	rna	rna	NOUN
american_scientific_journal-7186	193	36	expression	expression	NOUN
american_scientific_journal-7186	193	37	enabled	enable	VERB
american_scientific_journal-7186	193	38	highly	highly	ADV
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american_scientific_journal-7186	193	40	crispr	crispr	ADJ
american_scientific_journal-7186	193	41	/	/	SYM
american_scientific_journal-7186	193	42	cas9	cas9	NOUN
american_scientific_journal-7186	193	43	genome	genome	NOUN
american_scientific_journal-7186	193	44	editing	editing	NOUN
american_scientific_journal-7186	193	45	in	in	ADP
american_scientific_journal-7186	193	46	aspergillus	aspergillus	ADJ
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american_scientific_journal-7186	193	48	.	.	PUNCT
american_scientific_journal-7186	194	1	acs	acs	PROPN
american_scientific_journal-7186	194	2	synth	synth	PROPN
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american_scientific_journal-7186	194	4	.	.	PUNCT
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american_scientific_journal-7186	195	2	)	)	PUNCT
american_scientific_journal-7186	195	3	,	,	PUNCT
american_scientific_journal-7186	195	4	667	667	NUM
american_scientific_journal-7186	195	5	-	-	NUM
american_scientific_journal-7186	195	6	687	687	NUM
american_scientific_journal-7186	195	7	.	.	PUNCT
american_scientific_journal-7186	195	8	.	.	PUNCT
american_scientific_journal-7186	196	1	(	(	PUNCT
american_scientific_journal-7186	196	2	2018	2018	NUM
american_scientific_journal-7186	196	3	)	)	PUNCT
american_scientific_journal-7186	197	1	[	[	X
american_scientific_journal-7186	197	2	12	12	NUM
american_scientific_journal-7186	197	3	]	]	PUNCT
american_scientific_journal-7186	197	4	.	.	PUNCT
american_scientific_journal-7186	198	1	miao	miao	PROPN
american_scientific_journal-7186	198	2	,	,	PUNCT
american_scientific_journal-7186	198	3	j.	j.	PROPN
american_scientific_journal-7186	198	4	,	,	PUNCT
american_scientific_journal-7186	198	5	li	li	PROPN
american_scientific_journal-7186	198	6	,	,	PUNCT
american_scientific_journal-7186	198	7	x.	x.	PROPN
american_scientific_journal-7186	198	8	,	,	PUNCT
american_scientific_journal-7186	198	9	lin	lin	PROPN
american_scientific_journal-7186	198	10	,	,	PUNCT
american_scientific_journal-7186	198	11	d.	d.	PROPN
american_scientific_journal-7186	198	12	,	,	PUNCT
american_scientific_journal-7186	198	13	liu	liu	PROPN
american_scientific_journal-7186	198	14	,	,	PUNCT
american_scientific_journal-7186	198	15	x.	x.	PROPN
american_scientific_journal-7186	198	16	&	&	CCONJ
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american_scientific_journal-7186	198	18	,	,	PUNCT
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american_scientific_journal-7186	198	20	.	.	PROPN
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american_scientific_journal-7186	198	22	-	-	PUNCT
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american_scientific_journal-7186	198	27	2	2	NUM
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american_scientific_journal-7186	198	31	for	for	ADP
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american_scientific_journal-7186	198	33	sojae	sojae	NOUN
american_scientific_journal-7186	198	34	based	base	VERB
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american_scientific_journal-7186	198	36	crispr	crispr	ADJ
american_scientific_journal-7186	198	37	/	/	SYM
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american_scientific_journal-7186	198	40	.	.	PUNCT
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american_scientific_journal-7186	199	4	.	.	PROPN
american_scientific_journal-7186	199	5	10(84	10(84	PROPN
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american_scientific_journal-7186	199	7	,	,	PUNCT
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american_scientific_journal-7186	199	9	.	.	PUNCT
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american_scientific_journal-7186	200	3	)	)	PUNCT
american_scientific_journal-7186	200	4	.	.	PUNCT
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american_scientific_journal-7186	201	3	]	]	PUNCT
american_scientific_journal-7186	201	4	.	.	PUNCT
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american_scientific_journal-7186	201	6	,	,	PUNCT
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american_scientific_journal-7186	201	8	&	&	CCONJ
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american_scientific_journal-7186	201	10	,	,	PUNCT
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american_scientific_journal-7186	201	14	dna	dna	PROPN
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american_scientific_journal-7186	201	17	the	the	DET
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american_scientific_journal-7186	201	20	.	.	PUNCT
american_scientific_journal-7186	202	1	nat	nat	PROPN
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american_scientific_journal-7186	202	6	.	.	PUNCT
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american_scientific_journal-7186	203	3	,	,	PUNCT
american_scientific_journal-7186	203	4	297–308	297–308	NUM
american_scientific_journal-7186	203	5	.	.	PUNCT
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american_scientific_journal-7186	204	4	.	.	PUNCT
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american_scientific_journal-7186	205	4	.	.	PUNCT
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american_scientific_journal-7186	206	2	,	,	PUNCT
american_scientific_journal-7186	206	3	y.	y.	PROPN
american_scientific_journal-7186	206	4	,	,	PUNCT
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american_scientific_journal-7186	206	6	,	,	PUNCT
american_scientific_journal-7186	206	7	c.	c.	PROPN
american_scientific_journal-7186	206	8	,	,	PUNCT
american_scientific_journal-7186	206	9	liu	liu	PROPN
american_scientific_journal-7186	206	10	,	,	PUNCT
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american_scientific_journal-7186	206	12	,	,	PUNCT
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american_scientific_journal-7186	206	14	,	,	PUNCT
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american_scientific_journal-7186	206	16	,	,	PUNCT
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american_scientific_journal-7186	206	18	,	,	PUNCT
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american_scientific_journal-7186	206	20	,	,	PUNCT
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american_scientific_journal-7186	206	22	,	,	PUNCT
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american_scientific_journal-7186	206	24	,	,	PUNCT
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american_scientific_journal-7186	206	26	,	,	PUNCT
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american_scientific_journal-7186	206	29	,	,	PUNCT
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american_scientific_journal-7186	206	40	,	,	PUNCT
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american_scientific_journal-7186	206	42	,	,	PUNCT
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american_scientific_journal-7186	206	44	&	&	CCONJ
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american_scientific_journal-7186	206	46	,	,	PUNCT
american_scientific_journal-7186	206	47	c	c	X
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american_scientific_journal-7186	206	61	-	-	PUNCT
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american_scientific_journal-7186	207	1	sci	sci	PROPN
american_scientific_journal-7186	207	2	rep	rep	PROPN
american_scientific_journal-7186	207	3	.	.	PROPN
american_scientific_journal-7186	207	4	6(44	6(44	NUM
american_scientific_journal-7186	207	5	)	)	PUNCT
american_scientific_journal-7186	207	6	,	,	PUNCT
american_scientific_journal-7186	207	7	23890	23890	NUM
american_scientific_journal-7186	207	8	.	.	PUNCT
american_scientific_journal-7186	208	1	(	(	PUNCT
american_scientific_journal-7186	208	2	2016	2016	NUM
american_scientific_journal-7186	208	3	)	)	PUNCT
american_scientific_journal-7186	209	1	[	[	X
american_scientific_journal-7186	209	2	15	15	NUM
american_scientific_journal-7186	209	3	]	]	SYM
american_scientific_journal-7186	209	4	.	.	PUNCT
american_scientific_journal-7186	210	1	nagy	nagy	PROPN
american_scientific_journal-7186	210	2	,	,	PUNCT
american_scientific_journal-7186	210	3	g.	g.	PROPN
american_scientific_journal-7186	210	4	,	,	PUNCT
american_scientific_journal-7186	210	5	vaz	vaz	PROPN
american_scientific_journal-7186	210	6	,	,	PUNCT
american_scientific_journal-7186	210	7	a.g	a.g	PROPN
american_scientific_journal-7186	210	8	.	.	PROPN
american_scientific_journal-7186	210	9	,	,	PUNCT
american_scientific_journal-7186	210	10	szebenyi	szebenyi	PROPN
american_scientific_journal-7186	210	11	,	,	PUNCT
american_scientific_journal-7186	210	12	c.	c.	PROPN
american_scientific_journal-7186	210	13	,	,	PUNCT
american_scientific_journal-7186	210	14	takó	takó	PROPN
american_scientific_journal-7186	210	15	,	,	PUNCT
american_scientific_journal-7186	210	16	m.	m.	NOUN
american_scientific_journal-7186	210	17	,	,	PUNCT
american_scientific_journal-7186	210	18	tóth	tóth	PROPN
american_scientific_journal-7186	210	19	,	,	PUNCT
american_scientific_journal-7186	210	20	e.j	e.j	PROPN
american_scientific_journal-7186	210	21	.	.	PROPN
american_scientific_journal-7186	210	22	,	,	PUNCT
american_scientific_journal-7186	210	23	csernetics	csernetics	PROPN
american_scientific_journal-7186	210	24	,	,	PUNCT
american_scientific_journal-7186	210	25	a.	a.	NOUN
american_scientific_journal-7186	210	26	,	,	PUNCT
american_scientific_journal-7186	210	27	bencsik	bencsik	NOUN
american_scientific_journal-7186	210	28	,	,	PUNCT
american_scientific_journal-7186	210	29	o.	o.	PROPN
american_scientific_journal-7186	210	30	,	,	PUNCT
american_scientific_journal-7186	210	31	szekeres	szekere	VERB
american_scientific_journal-7186	210	32	,	,	PUNCT
american_scientific_journal-7186	210	33	a.	a.	NOUN
american_scientific_journal-7186	210	34	,	,	PUNCT
american_scientific_journal-7186	210	35	homa	homa	PROPN
american_scientific_journal-7186	210	36	,	,	PUNCT
american_scientific_journal-7186	210	37	m.	m.	NOUN
american_scientific_journal-7186	210	38	,	,	PUNCT
american_scientific_journal-7186	210	39	ayaydin	ayaydin	PROPN
american_scientific_journal-7186	210	40	,	,	PUNCT
american_scientific_journal-7186	210	41	f.	f.	PROPN
american_scientific_journal-7186	210	42	,	,	PUNCT
american_scientific_journal-7186	210	43	galgóczy	galgóczy	PROPN
american_scientific_journal-7186	210	44	,	,	PUNCT
american_scientific_journal-7186	210	45	l.	l.	PROPN
american_scientific_journal-7186	210	46	,	,	PUNCT
american_scientific_journal-7186	210	47	vágvölgyi	vágvölgyi	PROPN
american_scientific_journal-7186	210	48	,	,	PUNCT
american_scientific_journal-7186	210	49	c.	c.	PROPN
american_scientific_journal-7186	210	50	&	&	CCONJ
american_scientific_journal-7186	210	51	papp	papp	PROPN
american_scientific_journal-7186	210	52	,	,	PUNCT
american_scientific_journal-7186	210	53	t.	t.	PROPN
american_scientific_journal-7186	210	54	crispr	crispr	NOUN
american_scientific_journal-7186	210	55	-	-	PUNCT
american_scientific_journal-7186	210	56	cas9	cas9	NOUN
american_scientific_journal-7186	210	57	-	-	PUNCT
american_scientific_journal-7186	210	58	mediated	mediate	VERB
american_scientific_journal-7186	210	59	disruption	disruption	NOUN
american_scientific_journal-7186	210	60	of	of	ADP
american_scientific_journal-7186	210	61	the	the	DET
american_scientific_journal-7186	210	62	hmgcoa	hmgcoa	NOUN
american_scientific_journal-7186	210	63	reductase	reductase	NOUN
american_scientific_journal-7186	210	64	genes	gene	NOUN
american_scientific_journal-7186	210	65	of	of	ADP
american_scientific_journal-7186	210	66	mucorcircinelloides	mucorcircinelloide	NOUN
american_scientific_journal-7186	210	67	and	and	CCONJ
american_scientific_journal-7186	210	68	subcellular	subcellular	ADJ
american_scientific_journal-7186	210	69	localization	localization	NOUN
american_scientific_journal-7186	210	70	of	of	ADP
american_scientific_journal-7186	210	71	the	the	DET
american_scientific_journal-7186	210	72	encoded	encode	VERB
american_scientific_journal-7186	210	73	enzymes	enzyme	NOUN
american_scientific_journal-7186	210	74	.	.	PUNCT
american_scientific_journal-7186	211	1	fungal	fungal	ADJ
american_scientific_journal-7186	211	2	genet	genet	PROPN
american_scientific_journal-7186	211	3	biol	biol	PROPN
american_scientific_journal-7186	211	4	.	.	PUNCT
american_scientific_journal-7186	212	1	129(56	129(56	NUM
american_scientific_journal-7186	212	2	)	)	PUNCT
american_scientific_journal-7186	212	3	,	,	PUNCT
american_scientific_journal-7186	213	1	30–39	30–39	NUM
american_scientific_journal-7186	213	2	.	.	PUNCT
american_scientific_journal-7186	214	1	(	(	PUNCT
american_scientific_journal-7186	214	2	2019	2019	NUM
american_scientific_journal-7186	214	3	)	)	PUNCT
american_scientific_journal-7186	214	4	.	.	PUNCT
american_scientific_journal-7186	215	1	[	[	X
american_scientific_journal-7186	215	2	16	16	NUM
american_scientific_journal-7186	215	3	]	]	PUNCT
american_scientific_journal-7186	215	4	.	.	PUNCT
american_scientific_journal-7186	216	1	kuscu	kuscu	PROPN
american_scientific_journal-7186	216	2	,	,	PUNCT
american_scientific_journal-7186	216	3	c.	c.	PROPN
american_scientific_journal-7186	216	4	,	,	PUNCT
american_scientific_journal-7186	216	5	arslan	arslan	PROPN
american_scientific_journal-7186	216	6	,	,	PUNCT
american_scientific_journal-7186	216	7	s.	s.	PROPN
american_scientific_journal-7186	216	8	,	,	PUNCT
american_scientific_journal-7186	216	9	singh	singh	PROPN
american_scientific_journal-7186	216	10	,	,	PUNCT
american_scientific_journal-7186	216	11	r.	r.	PROPN
american_scientific_journal-7186	216	12	,	,	PUNCT
american_scientific_journal-7186	216	13	thorpe	thorpe	PROPN
american_scientific_journal-7186	216	14	,	,	PUNCT
american_scientific_journal-7186	216	15	j.	j.	PROPN
american_scientific_journal-7186	216	16	&	&	CCONJ
american_scientific_journal-7186	216	17	adli	adli	PROPN
american_scientific_journal-7186	216	18	,	,	PUNCT
american_scientific_journal-7186	216	19	m.	m.	NOUN
american_scientific_journal-7186	216	20	genome	genome	NOUN
american_scientific_journal-7186	216	21	-	-	PUNCT
american_scientific_journal-7186	216	22	wide	wide	ADJ
american_scientific_journal-7186	216	23	analysis	analysis	NOUN
american_scientific_journal-7186	216	24	reveals	reveal	VERB
american_scientific_journal-7186	216	25	characteristics	characteristic	NOUN
american_scientific_journal-7186	216	26	of	of	ADP
american_scientific_journal-7186	216	27	off	off	ADP
american_scientific_journal-7186	216	28	-	-	PUNCT
american_scientific_journal-7186	216	29	target	target	NOUN
american_scientific_journal-7186	216	30	sites	site	NOUN
american_scientific_journal-7186	216	31	bound	bind	VERB
american_scientific_journal-7186	216	32	by	by	ADP
american_scientific_journal-7186	216	33	the	the	DET
american_scientific_journal-7186	216	34	cas9	cas9	NOUN
american_scientific_journal-7186	216	35	endonuclease	endonuclease	NOUN
american_scientific_journal-7186	216	36	.	.	PUNCT
american_scientific_journal-7186	217	1	nat	nat	PROPN
american_scientific_journal-7186	217	2	biotechnol	biotechnol	NOUN
american_scientific_journal-7186	217	3	.	.	PUNCT
american_scientific_journal-7186	218	1	32(88	32(88	NUM
american_scientific_journal-7186	218	2	)	)	PUNCT
american_scientific_journal-7186	218	3	,	,	PUNCT
american_scientific_journal-7186	218	4	677–683	677–683	NUM
american_scientific_journal-7186	218	5	.	.	PUNCT
american_scientific_journal-7186	219	1	(	(	PUNCT
american_scientific_journal-7186	219	2	2014	2014	NUM
american_scientific_journal-7186	219	3	)	)	PUNCT
american_scientific_journal-7186	219	4	.	.	PUNCT
american_scientific_journal-7186	220	1	[	[	X
american_scientific_journal-7186	220	2	17	17	NUM
american_scientific_journal-7186	220	3	]	]	PUNCT
american_scientific_journal-7186	220	4	.	.	PUNCT
american_scientific_journal-7186	221	1	tsai	tsai	PROPN
american_scientific_journal-7186	221	2	,	,	PUNCT
american_scientific_journal-7186	221	3	s.q	s.q	PROPN
american_scientific_journal-7186	221	4	.	.	PROPN
american_scientific_journal-7186	221	5	,	,	PUNCT
american_scientific_journal-7186	221	6	zheng	zheng	PROPN
american_scientific_journal-7186	221	7	,	,	PUNCT
american_scientific_journal-7186	221	8	z.	z.	PROPN
american_scientific_journal-7186	221	9	,	,	PUNCT
american_scientific_journal-7186	221	10	nguyen	nguyen	PROPN
american_scientific_journal-7186	221	11	,	,	PUNCT
american_scientific_journal-7186	221	12	n.t	n.t	PROPN
american_scientific_journal-7186	221	13	.	.	PROPN
american_scientific_journal-7186	221	14	,	,	PUNCT
american_scientific_journal-7186	221	15	liebers	lieber	NOUN
american_scientific_journal-7186	221	16	,	,	PUNCT
american_scientific_journal-7186	221	17	m.	m.	NOUN
american_scientific_journal-7186	221	18	,	,	PUNCT
american_scientific_journal-7186	221	19	topkar	topkar	NOUN
american_scientific_journal-7186	221	20	,	,	PUNCT
american_scientific_journal-7186	221	21	v.v	v.v	PROPN
american_scientific_journal-7186	221	22	.	.	PROPN
american_scientific_journal-7186	221	23	,	,	PUNCT
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american_scientific_journal-7186	221	25	,	,	PUNCT
american_scientific_journal-7186	221	26	v.	v.	PROPN
american_scientific_journal-7186	221	27	,	,	PUNCT
american_scientific_journal-7186	221	28	wyvekens	wyvekens	PROPN
american_scientific_journal-7186	221	29	,	,	PUNCT
american_scientific_journal-7186	221	30	n.	n.	NOUN
american_scientific_journal-7186	221	31	,	,	PUNCT
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american_scientific_journal-7186	221	33	,	,	PUNCT
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american_scientific_journal-7186	221	35	,	,	PUNCT
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american_scientific_journal-7186	221	37	,	,	PUNCT
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american_scientific_journal-7186	221	40	,	,	PUNCT
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american_scientific_journal-7186	221	44	.	.	PROPN
american_scientific_journal-7186	221	45	,	,	PUNCT
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american_scientific_journal-7186	221	47	,	,	PUNCT
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american_scientific_journal-7186	221	50	,	,	PUNCT
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american_scientific_journal-7186	221	52	,	,	PUNCT
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american_scientific_journal-7186	221	54	.	.	PROPN
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american_scientific_journal-7186	221	56	-	-	PUNCT
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american_scientific_journal-7186	221	58	enables	enable	VERB
american_scientific_journal-7186	221	59	genome	genome	NOUN
american_scientific_journal-7186	221	60	-	-	PUNCT
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american_scientific_journal-7186	221	63	of	of	ADP
american_scientific_journal-7186	221	64	offtarget	offtarget	NOUN
american_scientific_journal-7186	221	65	cleavage	cleavage	NOUN
american_scientific_journal-7186	221	66	by	by	ADP
american_scientific_journal-7186	221	67	crispr	crispr	ADJ
american_scientific_journal-7186	221	68	-	-	PUNCT
american_scientific_journal-7186	221	69	cas	cas	NOUN
american_scientific_journal-7186	221	70	nucleases	nuclease	NOUN
american_scientific_journal-7186	221	71	.	.	PUNCT
american_scientific_journal-7186	222	1	nat	nat	PROPN
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american_scientific_journal-7186	222	3	.	.	PUNCT
american_scientific_journal-7186	223	1	33(45	33(45	ADJ
american_scientific_journal-7186	223	2	)	)	PUNCT
american_scientific_journal-7186	223	3	,	,	PUNCT
american_scientific_journal-7186	223	4	187–197	187–197	NUM
american_scientific_journal-7186	223	5	.	.	PUNCT
american_scientific_journal-7186	224	1	(	(	PUNCT
american_scientific_journal-7186	224	2	2015	2015	NUM
american_scientific_journal-7186	224	3	)	)	PUNCT
american_scientific_journal-7186	224	4	.	.	PUNCT
american_scientific_journal-7186	225	1	[	[	X
american_scientific_journal-7186	225	2	18	18	NUM
american_scientific_journal-7186	225	3	]	]	PUNCT
american_scientific_journal-7186	225	4	.	.	PUNCT
american_scientific_journal-7186	226	1	kim	kim	PROPN
american_scientific_journal-7186	226	2	,	,	PUNCT
american_scientific_journal-7186	226	3	d.	d.	PROPN
american_scientific_journal-7186	226	4	,	,	PUNCT
american_scientific_journal-7186	226	5	bae	bae	PROPN
american_scientific_journal-7186	226	6	,	,	PUNCT
american_scientific_journal-7186	226	7	s.	s.	PROPN
american_scientific_journal-7186	226	8	,	,	PUNCT
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american_scientific_journal-7186	226	10	,	,	PUNCT
american_scientific_journal-7186	226	11	j.	j.	PROPN
american_scientific_journal-7186	226	12	,	,	PUNCT
american_scientific_journal-7186	226	13	kim	kim	PROPN
american_scientific_journal-7186	226	14	,	,	PUNCT
american_scientific_journal-7186	226	15	e.	e.	PROPN
american_scientific_journal-7186	226	16	,	,	PUNCT
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american_scientific_journal-7186	226	18	,	,	PUNCT
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american_scientific_journal-7186	226	20	,	,	PUNCT
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american_scientific_journal-7186	226	22	,	,	PUNCT
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american_scientific_journal-7186	226	25	,	,	PUNCT
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american_scientific_journal-7186	226	27	,	,	PUNCT
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american_scientific_journal-7186	226	29	,	,	PUNCT
american_scientific_journal-7186	226	30	kim	kim	PROPN
american_scientific_journal-7186	226	31	,	,	PUNCT
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american_scientific_journal-7186	226	33	.	.	PROPN
american_scientific_journal-7186	226	34	&	&	CCONJ
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american_scientific_journal-7186	226	36	,	,	PUNCT
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american_scientific_journal-7186	226	38	.	.	PROPN
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american_scientific_journal-7186	226	40	:	:	PUNCT
american_scientific_journal-7186	226	41	genome	genome	NOUN
american_scientific_journal-7186	226	42	-	-	PUNCT
american_scientific_journal-7186	226	43	wideprofilingofcrispr	wideprofilingofcrispr	NOUN
american_scientific_journal-7186	226	44	-	-	PUNCT
american_scientific_journal-7186	226	45	cas9offtarget	cas9offtarget	NOUN
american_scientific_journal-7186	226	46	effects	effect	NOUN
american_scientific_journal-7186	226	47	in	in	ADP
american_scientific_journal-7186	226	48	human	human	ADJ
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american_scientific_journal-7186	226	50	.	.	PUNCT
american_scientific_journal-7186	227	1	nat	nat	NOUN
american_scientific_journal-7186	227	2	methods	method	NOUN
american_scientific_journal-7186	227	3	.	.	PUNCT
american_scientific_journal-7186	228	1	12(237	12(237	PROPN
american_scientific_journal-7186	228	2	-	-	PUNCT
american_scientific_journal-7186	228	3	243	243	NUM
american_scientific_journal-7186	228	4	)	)	PUNCT
american_scientific_journal-7186	228	5	,	,	PUNCT
american_scientific_journal-7186	228	6	1–243	1–243	NUM
american_scientific_journal-7186	228	7	.	.	PUNCT
american_scientific_journal-7186	229	1	(	(	PUNCT
american_scientific_journal-7186	229	2	2015	2015	NUM
american_scientific_journal-7186	229	3	)	)	PUNCT
american_scientific_journal-7186	229	4	.	.	PUNCT
american_scientific_journal-7186	230	1	[	[	X
american_scientific_journal-7186	230	2	19	19	NUM
american_scientific_journal-7186	230	3	]	]	PUNCT
american_scientific_journal-7186	230	4	.	.	PUNCT
american_scientific_journal-7186	231	1	katayama	katayama	PROPN
american_scientific_journal-7186	231	2	,	,	PUNCT
american_scientific_journal-7186	231	3	t.	t.	PROPN
american_scientific_journal-7186	231	4	,	,	PUNCT
american_scientific_journal-7186	231	5	tanaka	tanaka	PROPN
american_scientific_journal-7186	231	6	,	,	PUNCT
american_scientific_journal-7186	231	7	y.	y.	PROPN
american_scientific_journal-7186	231	8	,	,	PUNCT
american_scientific_journal-7186	231	9	okabe	okabe	NOUN
american_scientific_journal-7186	231	10	,	,	PUNCT
american_scientific_journal-7186	231	11	t.	t.	PROPN
american_scientific_journal-7186	231	12	,	,	PUNCT
american_scientific_journal-7186	231	13	nakamura	nakamura	PROPN
american_scientific_journal-7186	231	14	,	,	PUNCT
american_scientific_journal-7186	231	15	h.	h.	PROPN
american_scientific_journal-7186	231	16	,	,	PUNCT
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american_scientific_journal-7186	231	18	,	,	PUNCT
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american_scientific_journal-7186	231	20	,	,	PUNCT
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american_scientific_journal-7186	231	22	,	,	PUNCT
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american_scientific_journal-7186	231	24	,	,	PUNCT
american_scientific_journal-7186	231	25	&	&	CCONJ
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american_scientific_journal-7186	231	27	,	,	PUNCT
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