id	sid	tid	token	lemma	pos
american_scientific_journal-766	1	1	american	american	PROPN
american_scientific_journal-766	1	2	scientific	scientific	ADJ
american_scientific_journal-766	1	3	research	research	NOUN
american_scientific_journal-766	1	4	journal	journal	NOUN
american_scientific_journal-766	1	5	for	for	ADP
american_scientific_journal-766	1	6	engineering	engineering	NOUN
american_scientific_journal-766	1	7	,	,	PUNCT
american_scientific_journal-766	1	8	technology	technology	NOUN
american_scientific_journal-766	1	9	,	,	PUNCT
american_scientific_journal-766	1	10	and	and	CCONJ
american_scientific_journal-766	1	11	sciences	science	NOUN
american_scientific_journal-766	1	12	(	(	PUNCT
american_scientific_journal-766	1	13	asrjets	asrjet	NOUN
american_scientific_journal-766	1	14	)	)	PUNCT
american_scientific_journal-766	1	15	issn	issn	PROPN
american_scientific_journal-766	1	16	(	(	PUNCT
american_scientific_journal-766	1	17	print	print	NOUN
american_scientific_journal-766	1	18	)	)	PUNCT
american_scientific_journal-766	1	19	2313	2313	NUM
american_scientific_journal-766	1	20	-	-	SYM
american_scientific_journal-766	1	21	4410	4410	NUM
american_scientific_journal-766	1	22	,	,	PUNCT
american_scientific_journal-766	1	23	issn	issn	PROPN
american_scientific_journal-766	1	24	(	(	PUNCT
american_scientific_journal-766	1	25	online	online	ADJ
american_scientific_journal-766	1	26	)	)	PUNCT
american_scientific_journal-766	1	27	2313	2313	NUM
american_scientific_journal-766	1	28	-	-	SYM
american_scientific_journal-766	1	29	4402	4402	NUM
american_scientific_journal-766	1	30	©	©	PROPN
american_scientific_journal-766	1	31	global	global	ADJ
american_scientific_journal-766	1	32	society	society	NOUN
american_scientific_journal-766	1	33	of	of	ADP
american_scientific_journal-766	1	34	scientific	scientific	ADJ
american_scientific_journal-766	1	35	research	research	NOUN
american_scientific_journal-766	1	36	and	and	CCONJ
american_scientific_journal-766	1	37	researchers	researcher	NOUN
american_scientific_journal-766	1	38	http://asrjetsjournal.org/	http://asrjetsjournal.org/	NOUN
american_scientific_journal-766	1	39	medication	medication	NOUN
american_scientific_journal-766	1	40	of	of	ADP
american_scientific_journal-766	1	41	chronic	chronic	ADJ
american_scientific_journal-766	1	42	hepatitis	hepatitis	NOUN
american_scientific_journal-766	1	43	c	c	NOUN
american_scientific_journal-766	1	44	:	:	PUNCT
american_scientific_journal-766	1	45	a	a	DET
american_scientific_journal-766	1	46	review	review	NOUN
american_scientific_journal-766	1	47	on	on	ADP
american_scientific_journal-766	1	48	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	1	49	as	as	ADP
american_scientific_journal-766	1	50	a	a	DET
american_scientific_journal-766	1	51	new	new	ADJ
american_scientific_journal-766	1	52	antiviral	antiviral	ADJ
american_scientific_journal-766	1	53	drug	drug	NOUN
american_scientific_journal-766	1	54	adel	adel	PROPN
american_scientific_journal-766	1	55	abdel	abdel	PROPN
american_scientific_journal-766	1	56	-	-	PUNCT
american_scientific_journal-766	1	57	moneima	moneima	PROPN
american_scientific_journal-766	1	58	*	*	NOUN
american_scientific_journal-766	1	59	,	,	PUNCT
american_scientific_journal-766	1	60	shimaa	shimaa	VERB
american_scientific_journal-766	1	61	ramadanb	ramadanb	PROPN
american_scientific_journal-766	1	62	aphysiology	aphysiology	NOUN
american_scientific_journal-766	1	63	division	division	NOUN
american_scientific_journal-766	1	64	,	,	PUNCT
american_scientific_journal-766	1	65	zoology	zoology	NOUN
american_scientific_journal-766	1	66	department	department	PROPN
american_scientific_journal-766	1	67	,	,	PUNCT
american_scientific_journal-766	1	68	faculty	faculty	NOUN
american_scientific_journal-766	1	69	of	of	ADP
american_scientific_journal-766	1	70	science	science	NOUN
american_scientific_journal-766	1	71	,	,	PUNCT
american_scientific_journal-766	1	72	beni	beni	ADJ
american_scientific_journal-766	1	73	-	-	ADJ
american_scientific_journal-766	1	74	suef	suef	ADJ
american_scientific_journal-766	1	75	university	university	NOUN
american_scientific_journal-766	1	76	,	,	PUNCT
american_scientific_journal-766	1	77	beni	beni	NOUN
american_scientific_journal-766	1	78	-	-	ADJ
american_scientific_journal-766	1	79	suef	suef	ADJ
american_scientific_journal-766	1	80	,	,	PUNCT
american_scientific_journal-766	1	81	egypt	egypt	PROPN
american_scientific_journal-766	1	82	.	.	PUNCT
american_scientific_journal-766	2	1	bzoology	bzoology	NOUN
american_scientific_journal-766	2	2	/	/	SYM
american_scientific_journal-766	2	3	chemistry	chemistry	NOUN
american_scientific_journal-766	2	4	student	student	NOUN
american_scientific_journal-766	2	5	,	,	PUNCT
american_scientific_journal-766	2	6	faculty	faculty	NOUN
american_scientific_journal-766	2	7	of	of	ADP
american_scientific_journal-766	2	8	science	science	NOUN
american_scientific_journal-766	2	9	,	,	PUNCT
american_scientific_journal-766	2	10	beni	beni	ADJ
american_scientific_journal-766	2	11	-	-	ADJ
american_scientific_journal-766	2	12	suef	suef	ADJ
american_scientific_journal-766	2	13	university	university	NOUN
american_scientific_journal-766	2	14	,	,	PUNCT
american_scientific_journal-766	2	15	beni	beni	NOUN
american_scientific_journal-766	2	16	-	-	ADJ
american_scientific_journal-766	2	17	suef	suef	ADJ
american_scientific_journal-766	2	18	,	,	PUNCT
american_scientific_journal-766	2	19	egypt	egypt	PROPN
american_scientific_journal-766	2	20	.	.	PUNCT
american_scientific_journal-766	3	1	aemail:shemasmart@yahoo.com	aemail:shemasmart@yahoo.com	PROPN
american_scientific_journal-766	3	2	bemail:adel_men2020@yahoo.com	bemail:adel_men2020@yahoo.com	PROPN
american_scientific_journal-766	3	3	abstract	abstract	NOUN
american_scientific_journal-766	3	4	in	in	ADP
american_scientific_journal-766	3	5	the	the	DET
american_scientific_journal-766	3	6	last	last	ADJ
american_scientific_journal-766	3	7	decade	decade	NOUN
american_scientific_journal-766	3	8	,	,	PUNCT
american_scientific_journal-766	3	9	standard	standard	NOUN
american_scientific_journal-766	3	10	of	of	ADP
american_scientific_journal-766	3	11	care	care	NOUN
american_scientific_journal-766	3	12	(	(	PUNCT
american_scientific_journal-766	3	13	soc	soc	NOUN
american_scientific_journal-766	3	14	)	)	PUNCT
american_scientific_journal-766	3	15	anti	anti	ADJ
american_scientific_journal-766	3	16	-	-	ADJ
american_scientific_journal-766	3	17	hcv	hcv	ADJ
american_scientific_journal-766	3	18	treatment	treatment	NOUN
american_scientific_journal-766	3	19	has	have	AUX
american_scientific_journal-766	3	20	been	be	AUX
american_scientific_journal-766	3	21	represented	represent	VERB
american_scientific_journal-766	3	22	by	by	ADP
american_scientific_journal-766	3	23	the	the	DET
american_scientific_journal-766	3	24	combination	combination	NOUN
american_scientific_journal-766	3	25	of	of	ADP
american_scientific_journal-766	3	26	peginterferon	peginterferon	NOUN
american_scientific_journal-766	3	27	(	(	PUNCT
american_scientific_journal-766	3	28	peg	peg	NOUN
american_scientific_journal-766	3	29	-	-	PUNCT
american_scientific_journal-766	3	30	ifn	ifn	NOUN
american_scientific_journal-766	3	31	)	)	PUNCT
american_scientific_journal-766	3	32	plus	plus	CCONJ
american_scientific_journal-766	3	33	ribavirin	ribavirin	NOUN
american_scientific_journal-766	3	34	(	(	PUNCT
american_scientific_journal-766	3	35	rbv	rbv	NOUN
american_scientific_journal-766	3	36	)	)	PUNCT
american_scientific_journal-766	3	37	.	.	PUNCT
american_scientific_journal-766	4	1	the	the	DET
american_scientific_journal-766	4	2	main	main	ADJ
american_scientific_journal-766	4	3	disadvantages	disadvantage	NOUN
american_scientific_journal-766	4	4	of	of	ADP
american_scientific_journal-766	4	5	peg	peg	NOUN
american_scientific_journal-766	4	6	-	-	PUNCT
american_scientific_journal-766	4	7	ifn	ifn	PROPN
american_scientific_journal-766	4	8	plus	plus	CCONJ
american_scientific_journal-766	4	9	rbv	rbv	PROPN
american_scientific_journal-766	4	10	therapy	therapy	NOUN
american_scientific_journal-766	4	11	were	be	AUX
american_scientific_journal-766	4	12	suboptimal	suboptimal	ADJ
american_scientific_journal-766	4	13	rates	rate	NOUN
american_scientific_journal-766	4	14	of	of	ADP
american_scientific_journal-766	4	15	sustained	sustain	VERB
american_scientific_journal-766	4	16	virological	virological	ADJ
american_scientific_journal-766	4	17	response	response	NOUN
american_scientific_journal-766	4	18	(	(	PUNCT
american_scientific_journal-766	4	19	svr	svr	PROPN
american_scientific_journal-766	4	20	)	)	PUNCT
american_scientific_journal-766	4	21	in	in	ADP
american_scientific_journal-766	4	22	difficult	difficult	ADJ
american_scientific_journal-766	4	23	-	-	PUNCT
american_scientific_journal-766	4	24	to	to	ADP
american_scientific_journal-766	4	25	-	-	PUNCT
american_scientific_journal-766	4	26	treat	treat	VERB
american_scientific_journal-766	4	27	patients	patient	NOUN
american_scientific_journal-766	4	28	and	and	CCONJ
american_scientific_journal-766	4	29	side	side	NOUN
american_scientific_journal-766	4	30	effects	effect	NOUN
american_scientific_journal-766	4	31	profile	profile	VERB
american_scientific_journal-766	4	32	resulting	result	VERB
american_scientific_journal-766	4	33	in	in	ADP
american_scientific_journal-766	4	34	poor	poor	ADJ
american_scientific_journal-766	4	35	tolerability	tolerability	NOUN
american_scientific_journal-766	4	36	.	.	PUNCT
american_scientific_journal-766	5	1	therefore	therefore	ADV
american_scientific_journal-766	5	2	,	,	PUNCT
american_scientific_journal-766	5	3	strategies	strategy	NOUN
american_scientific_journal-766	5	4	to	to	PART
american_scientific_journal-766	5	5	improve	improve	VERB
american_scientific_journal-766	5	6	svr	svr	PROPN
american_scientific_journal-766	5	7	rates	rate	NOUN
american_scientific_journal-766	5	8	and	and	CCONJ
american_scientific_journal-766	5	9	limited	limited	ADJ
american_scientific_journal-766	5	10	side	side	NOUN
american_scientific_journal-766	5	11	effects	effect	NOUN
american_scientific_journal-766	5	12	have	have	AUX
american_scientific_journal-766	5	13	been	be	AUX
american_scientific_journal-766	5	14	an	an	DET
american_scientific_journal-766	5	15	important	important	ADJ
american_scientific_journal-766	5	16	issue	issue	NOUN
american_scientific_journal-766	5	17	for	for	ADP
american_scientific_journal-766	5	18	clinical	clinical	ADJ
american_scientific_journal-766	5	19	physicians	physician	NOUN
american_scientific_journal-766	5	20	.	.	PUNCT
american_scientific_journal-766	6	1	recently	recently	ADV
american_scientific_journal-766	6	2	,	,	PUNCT
american_scientific_journal-766	6	3	direct	direct	ADJ
american_scientific_journal-766	6	4	antiviral	antiviral	ADJ
american_scientific_journal-766	6	5	agents	agent	NOUN
american_scientific_journal-766	6	6	(	(	PUNCT
american_scientific_journal-766	6	7	daas	daas	NOUN
american_scientific_journal-766	6	8	)	)	PUNCT
american_scientific_journal-766	6	9	opened	open	VERB
american_scientific_journal-766	6	10	the	the	DET
american_scientific_journal-766	6	11	gate	gate	NOUN
american_scientific_journal-766	6	12	for	for	ADP
american_scientific_journal-766	6	13	a	a	DET
american_scientific_journal-766	6	14	new	new	ADJ
american_scientific_journal-766	6	15	era	era	NOUN
american_scientific_journal-766	6	16	for	for	ADP
american_scientific_journal-766	6	17	management	management	NOUN
american_scientific_journal-766	6	18	of	of	ADP
american_scientific_journal-766	6	19	hcv	hcv	NOUN
american_scientific_journal-766	6	20	and	and	CCONJ
american_scientific_journal-766	6	21	have	have	AUX
american_scientific_journal-766	6	22	revolutionized	revolutionize	VERB
american_scientific_journal-766	6	23	the	the	DET
american_scientific_journal-766	6	24	treatment	treatment	NOUN
american_scientific_journal-766	6	25	of	of	ADP
american_scientific_journal-766	6	26	chronic	chronic	ADJ
american_scientific_journal-766	6	27	hepatitis	hepatitis	NOUN
american_scientific_journal-766	6	28	c	c	PROPN
american_scientific_journal-766	6	29	(	(	PUNCT
american_scientific_journal-766	6	30	chc	chc	NOUN
american_scientific_journal-766	6	31	)	)	PUNCT
american_scientific_journal-766	6	32	patients	patient	NOUN
american_scientific_journal-766	6	33	.	.	PUNCT
american_scientific_journal-766	7	1	furthermore	furthermore	ADV
american_scientific_journal-766	7	2	,	,	PUNCT
american_scientific_journal-766	7	3	the	the	DET
american_scientific_journal-766	7	4	approval	approval	NOUN
american_scientific_journal-766	7	5	of	of	ADP
american_scientific_journal-766	7	6	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	7	7	by	by	ADP
american_scientific_journal-766	7	8	fda	fda	PROPN
american_scientific_journal-766	7	9	represents	represent	VERB
american_scientific_journal-766	7	10	the	the	DET
american_scientific_journal-766	7	11	first	first	ADJ
american_scientific_journal-766	7	12	key	key	ADJ
american_scientific_journal-766	7	13	step	step	NOUN
american_scientific_journal-766	7	14	towards	towards	ADP
american_scientific_journal-766	7	15	the	the	DET
american_scientific_journal-766	7	16	new	new	ADJ
american_scientific_journal-766	7	17	era	era	NOUN
american_scientific_journal-766	7	18	in	in	ADP
american_scientific_journal-766	7	19	the	the	DET
american_scientific_journal-766	7	20	management	management	NOUN
american_scientific_journal-766	7	21	of	of	ADP
american_scientific_journal-766	7	22	chc	chc	PROPN
american_scientific_journal-766	7	23	patients	patient	NOUN
american_scientific_journal-766	7	24	,	,	PUNCT
american_scientific_journal-766	7	25	since	since	SCONJ
american_scientific_journal-766	7	26	it	it	PRON
american_scientific_journal-766	7	27	is	be	AUX
american_scientific_journal-766	7	28	the	the	DET
american_scientific_journal-766	7	29	first	first	ADJ
american_scientific_journal-766	7	30	approved	approve	VERB
american_scientific_journal-766	7	31	daas	daas	NOUN
american_scientific_journal-766	7	32	with	with	ADP
american_scientific_journal-766	7	33	excellent	excellent	ADJ
american_scientific_journal-766	7	34	tolerability	tolerability	NOUN
american_scientific_journal-766	7	35	and	and	CCONJ
american_scientific_journal-766	7	36	favorable	favorable	ADJ
american_scientific_journal-766	7	37	pharmacokinetic	pharmacokinetic	ADJ
american_scientific_journal-766	7	38	profile	profile	NOUN
american_scientific_journal-766	7	39	,	,	PUNCT
american_scientific_journal-766	7	40	limited	limited	ADJ
american_scientific_journal-766	7	41	potential	potential	NOUN
american_scientific_journal-766	7	42	for	for	ADP
american_scientific_journal-766	7	43	drug	drug	NOUN
american_scientific_journal-766	7	44	interactions	interaction	NOUN
american_scientific_journal-766	7	45	,	,	PUNCT
american_scientific_journal-766	7	46	higher	high	ADJ
american_scientific_journal-766	7	47	specificity	specificity	NOUN
american_scientific_journal-766	7	48	,	,	PUNCT
american_scientific_journal-766	7	49	shorter	short	ADJ
american_scientific_journal-766	7	50	treatment	treatment	NOUN
american_scientific_journal-766	7	51	durations	duration	NOUN
american_scientific_journal-766	7	52	,	,	PUNCT
american_scientific_journal-766	7	53	low	low	ADJ
american_scientific_journal-766	7	54	side	side	NOUN
american_scientific_journal-766	7	55	effects	effect	NOUN
american_scientific_journal-766	7	56	,	,	PUNCT
american_scientific_journal-766	7	57	oral	oral	ADJ
american_scientific_journal-766	7	58	administration	administration	NOUN
american_scientific_journal-766	7	59	,	,	PUNCT
american_scientific_journal-766	7	60	potent	potent	ADJ
american_scientific_journal-766	7	61	antiviral	antiviral	ADJ
american_scientific_journal-766	7	62	activity	activity	NOUN
american_scientific_journal-766	7	63	and	and	CCONJ
american_scientific_journal-766	7	64	high	high	ADJ
american_scientific_journal-766	7	65	genetic	genetic	ADJ
american_scientific_journal-766	7	66	barrier	barrier	NOUN
american_scientific_journal-766	7	67	against	against	ADP
american_scientific_journal-766	7	68	all	all	DET
american_scientific_journal-766	7	69	hcv	hcv	NOUN
american_scientific_journal-766	7	70	genotypes	genotype	NOUN
american_scientific_journal-766	7	71	and	and	CCONJ
american_scientific_journal-766	7	72	acts	act	NOUN
american_scientific_journal-766	7	73	as	as	ADP
american_scientific_journal-766	7	74	a	a	DET
american_scientific_journal-766	7	75	chain	chain	NOUN
american_scientific_journal-766	7	76	terminator	terminator	NOUN
american_scientific_journal-766	7	77	during	during	ADP
american_scientific_journal-766	7	78	the	the	DET
american_scientific_journal-766	7	79	hcv	hcv	NOUN
american_scientific_journal-766	7	80	replication	replication	NOUN
american_scientific_journal-766	7	81	process	process	NOUN
american_scientific_journal-766	7	82	.	.	PUNCT
american_scientific_journal-766	8	1	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	8	2	efficacy	efficacy	PROPN
american_scientific_journal-766	8	3	and	and	CCONJ
american_scientific_journal-766	8	4	safety	safety	NOUN
american_scientific_journal-766	8	5	was	be	AUX
american_scientific_journal-766	8	6	demonstrated	demonstrate	VERB
american_scientific_journal-766	8	7	in	in	ADP
american_scientific_journal-766	8	8	many	many	ADJ
american_scientific_journal-766	8	9	large	large	ADJ
american_scientific_journal-766	8	10	and	and	CCONJ
american_scientific_journal-766	8	11	well	well	ADV
american_scientific_journal-766	8	12	-	-	PUNCT
american_scientific_journal-766	8	13	designed	design	VERB
american_scientific_journal-766	8	14	phase	phase	NOUN
american_scientific_journal-766	8	15	2	2	NUM
american_scientific_journal-766	8	16	and	and	CCONJ
american_scientific_journal-766	8	17	phase	phase	NOUN
american_scientific_journal-766	8	18	3	3	NUM
american_scientific_journal-766	8	19	clinical	clinical	ADJ
american_scientific_journal-766	8	20	trials	trial	NOUN
american_scientific_journal-766	8	21	like	like	ADP
american_scientific_journal-766	8	22	proton	proton	NOUN
american_scientific_journal-766	8	23	,	,	PUNCT
american_scientific_journal-766	8	24	atomic	atomic	NOUN
american_scientific_journal-766	8	25	,	,	PUNCT
american_scientific_journal-766	8	26	neutrino	neutrino	NOUN
american_scientific_journal-766	8	27	,	,	PUNCT
american_scientific_journal-766	8	28	electron	electron	NOUN
american_scientific_journal-766	8	29	,	,	PUNCT
american_scientific_journal-766	8	30	quantum	quantum	NOUN
american_scientific_journal-766	8	31	,	,	PUNCT
american_scientific_journal-766	8	32	fission	fission	NOUN
american_scientific_journal-766	8	33	,	,	PUNCT
american_scientific_journal-766	8	34	fusion	fusion	NOUN
american_scientific_journal-766	8	35	,	,	PUNCT
american_scientific_journal-766	8	36	positron	positron	NOUN
american_scientific_journal-766	8	37	and	and	CCONJ
american_scientific_journal-766	8	38	lonstar	lonstar	ADJ
american_scientific_journal-766	8	39	studies	study	NOUN
american_scientific_journal-766	8	40	.	.	PUNCT
american_scientific_journal-766	9	1	in	in	ADP
american_scientific_journal-766	9	2	this	this	DET
american_scientific_journal-766	9	3	concept	concept	NOUN
american_scientific_journal-766	9	4	,	,	PUNCT
american_scientific_journal-766	9	5	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	9	6	represents	represent	VERB
american_scientific_journal-766	9	7	an	an	DET
american_scientific_journal-766	9	8	almost	almost	ADV
american_scientific_journal-766	9	9	ideal	ideal	ADJ
american_scientific_journal-766	9	10	backbone	backbone	NOUN
american_scientific_journal-766	9	11	,	,	PUNCT
american_scientific_journal-766	9	12	especially	especially	ADV
american_scientific_journal-766	9	13	in	in	ADP
american_scientific_journal-766	9	14	difficult	difficult	ADJ
american_scientific_journal-766	9	15	-	-	PUNCT
american_scientific_journal-766	9	16	to	to	ADP
american_scientific_journal-766	9	17	-	-	PUNCT
american_scientific_journal-766	9	18	treat	treat	VERB
american_scientific_journal-766	9	19	chc	chc	NOUN
american_scientific_journal-766	9	20	patients	patient	NOUN
american_scientific_journal-766	9	21	with	with	ADP
american_scientific_journal-766	9	22	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	9	23	or	or	CCONJ
american_scientific_journal-766	9	24	liver	liver	NOUN
american_scientific_journal-766	9	25	impairment	impairment	NOUN
american_scientific_journal-766	9	26	,	,	PUNCT
american_scientific_journal-766	9	27	liver	liver	NOUN
american_scientific_journal-766	9	28	transplant	transplant	NOUN
american_scientific_journal-766	9	29	recipients	recipient	NOUN
american_scientific_journal-766	9	30	,	,	PUNCT
american_scientific_journal-766	9	31	and	and	CCONJ
american_scientific_journal-766	9	32	co	co	NOUN
american_scientific_journal-766	9	33	-	-	NOUN
american_scientific_journal-766	9	34	infection	infection	NOUN
american_scientific_journal-766	9	35	with	with	ADP
american_scientific_journal-766	9	36	hiv	hiv	PROPN
american_scientific_journal-766	9	37	.	.	PUNCT
american_scientific_journal-766	10	1	this	this	DET
american_scientific_journal-766	10	2	review	review	NOUN
american_scientific_journal-766	10	3	summarizes	summarize	VERB
american_scientific_journal-766	10	4	the	the	DET
american_scientific_journal-766	10	5	development	development	NOUN
american_scientific_journal-766	10	6	of	of	ADP
american_scientific_journal-766	10	7	different	different	ADJ
american_scientific_journal-766	10	8	anti	anti	ADJ
american_scientific_journal-766	10	9	-	-	ADJ
american_scientific_journal-766	10	10	hcv	hcv	ADJ
american_scientific_journal-766	10	11	agents	agent	NOUN
american_scientific_journal-766	10	12	,	,	PUNCT
american_scientific_journal-766	10	13	and	and	CCONJ
american_scientific_journal-766	10	14	also	also	ADV
american_scientific_journal-766	10	15	provides	provide	VERB
american_scientific_journal-766	10	16	an	an	DET
american_scientific_journal-766	10	17	overview	overview	NOUN
american_scientific_journal-766	10	18	of	of	ADP
american_scientific_journal-766	10	19	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	10	20	clinical	clinical	ADJ
american_scientific_journal-766	10	21	efficacy	efficacy	NOUN
american_scientific_journal-766	10	22	and	and	CCONJ
american_scientific_journal-766	10	23	discussing	discuss	VERB
american_scientific_journal-766	10	24	key	key	ADJ
american_scientific_journal-766	10	25	results	result	NOUN
american_scientific_journal-766	10	26	and	and	CCONJ
american_scientific_journal-766	10	27	potential	potential	ADJ
american_scientific_journal-766	10	28	future	future	ADJ
american_scientific_journal-766	10	29	developments	development	NOUN
american_scientific_journal-766	10	30	.	.	PUNCT
american_scientific_journal-766	11	1	keywords	keyword	NOUN
american_scientific_journal-766	11	2	:	:	PUNCT
american_scientific_journal-766	11	3	peginterferon	peginterferon	NOUN
american_scientific_journal-766	11	4	;	;	PUNCT
american_scientific_journal-766	11	5	chronic	chronic	ADJ
american_scientific_journal-766	11	6	hepatitis	hepatitis	NOUN
american_scientific_journal-766	11	7	c	c	NOUN
american_scientific_journal-766	11	8	;	;	PUNCT
american_scientific_journal-766	11	9	ribavirin	ribavirin	NOUN
american_scientific_journal-766	11	10	;	;	PUNCT
american_scientific_journal-766	11	11	direct	direct	ADJ
american_scientific_journal-766	11	12	antiviral	antiviral	ADJ
american_scientific_journal-766	11	13	agents	agent	NOUN
american_scientific_journal-766	11	14	;	;	PUNCT
american_scientific_journal-766	11	15	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	11	16	.	.	PUNCT
american_scientific_journal-766	12	1	-----------------------------------------------------------------------	-----------------------------------------------------------------------	PUNCT
american_scientific_journal-766	13	1	*	*	PUNCT
american_scientific_journal-766	13	2	corresponding	correspond	VERB
american_scientific_journal-766	13	3	author	author	NOUN
american_scientific_journal-766	13	4	.	.	PUNCT
american_scientific_journal-766	14	1	e	e	X
american_scientific_journal-766	14	2	-	-	NOUN
american_scientific_journal-766	14	3	mail	mail	NOUN
american_scientific_journal-766	14	4	address	address	NOUN
american_scientific_journal-766	14	5	:	:	PUNCT
american_scientific_journal-766	14	6	shemasmart@yahoo.com	shemasmart@yahoo.com	X
american_scientific_journal-766	14	7	.	.	PROPN
american_scientific_journal-766	14	8	1	1	NUM
american_scientific_journal-766	14	9	http://asrjetsjournal.org/	http://asrjetsjournal.org/	PROPN
american_scientific_journal-766	14	10	american	american	ADJ
american_scientific_journal-766	14	11	scientific	scientific	ADJ
american_scientific_journal-766	14	12	research	research	NOUN
american_scientific_journal-766	14	13	journal	journal	NOUN
american_scientific_journal-766	14	14	for	for	ADP
american_scientific_journal-766	14	15	engineering	engineering	NOUN
american_scientific_journal-766	14	16	,	,	PUNCT
american_scientific_journal-766	14	17	technology	technology	NOUN
american_scientific_journal-766	14	18	,	,	PUNCT
american_scientific_journal-766	14	19	and	and	CCONJ
american_scientific_journal-766	14	20	sciences	science	NOUN
american_scientific_journal-766	14	21	(	(	PUNCT
american_scientific_journal-766	14	22	asrjets	asrjet	NOUN
american_scientific_journal-766	14	23	)	)	PUNCT
american_scientific_journal-766	14	24	(	(	PUNCT
american_scientific_journal-766	14	25	2015	2015	NUM
american_scientific_journal-766	14	26	)	)	PUNCT
american_scientific_journal-766	14	27	volume	volume	NOUN
american_scientific_journal-766	14	28	13	13	NUM
american_scientific_journal-766	14	29	,	,	PUNCT
american_scientific_journal-766	14	30	no	no	DET
american_scientific_journal-766	14	31	1	1	NUM
american_scientific_journal-766	14	32	,	,	PUNCT
american_scientific_journal-766	14	33	pp	pp	ADV
american_scientific_journal-766	14	34	1	1	NUM
american_scientific_journal-766	14	35	-	-	SYM
american_scientific_journal-766	14	36	23	23	NUM
american_scientific_journal-766	14	37	1	1	NUM
american_scientific_journal-766	14	38	.	.	PUNCT
american_scientific_journal-766	15	1	introduction	introduction	NOUN
american_scientific_journal-766	15	2	chronic	chronic	ADJ
american_scientific_journal-766	15	3	hepatitis	hepatitis	PROPN
american_scientific_journal-766	15	4	c	c	PROPN
american_scientific_journal-766	15	5	virus	virus	NOUN
american_scientific_journal-766	15	6	(	(	PUNCT
american_scientific_journal-766	15	7	hcv	hcv	NOUN
american_scientific_journal-766	15	8	)	)	PUNCT
american_scientific_journal-766	15	9	infection	infection	NOUN
american_scientific_journal-766	15	10	is	be	AUX
american_scientific_journal-766	15	11	currently	currently	ADV
american_scientific_journal-766	15	12	a	a	DET
american_scientific_journal-766	15	13	major	major	ADJ
american_scientific_journal-766	15	14	global	global	ADJ
american_scientific_journal-766	15	15	health	health	NOUN
american_scientific_journal-766	15	16	problem	problem	NOUN
american_scientific_journal-766	15	17	that	that	PRON
american_scientific_journal-766	15	18	affects	affect	VERB
american_scientific_journal-766	15	19	170	170	NUM
american_scientific_journal-766	15	20	million	million	NUM
american_scientific_journal-766	15	21	people	people	NOUN
american_scientific_journal-766	15	22	worldwide	worldwide	ADV
american_scientific_journal-766	15	23	and	and	CCONJ
american_scientific_journal-766	15	24	is	be	AUX
american_scientific_journal-766	15	25	one	one	NUM
american_scientific_journal-766	15	26	of	of	ADP
american_scientific_journal-766	15	27	the	the	DET
american_scientific_journal-766	15	28	main	main	ADJ
american_scientific_journal-766	15	29	causes	cause	NOUN
american_scientific_journal-766	15	30	of	of	ADP
american_scientific_journal-766	15	31	chronic	chronic	ADJ
american_scientific_journal-766	15	32	liver	liver	NOUN
american_scientific_journal-766	15	33	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	15	34	and	and	CCONJ
american_scientific_journal-766	15	35	hepatocellular	hepatocellular	ADJ
american_scientific_journal-766	15	36	carcinoma	carcinoma	NOUN
american_scientific_journal-766	16	1	[	[	X
american_scientific_journal-766	16	2	1	1	NUM
american_scientific_journal-766	16	3	]	]	PUNCT
american_scientific_journal-766	16	4	.	.	PUNCT
american_scientific_journal-766	17	1	epidemiological	epidemiological	ADJ
american_scientific_journal-766	17	2	studies	study	NOUN
american_scientific_journal-766	17	3	indicate	indicate	VERB
american_scientific_journal-766	17	4	that	that	SCONJ
american_scientific_journal-766	17	5	each	each	DET
american_scientific_journal-766	17	6	year	year	NOUN
american_scientific_journal-766	17	7	approximately	approximately	ADV
american_scientific_journal-766	17	8	3	3	NUM
american_scientific_journal-766	17	9	-	-	SYM
american_scientific_journal-766	17	10	4	4	NUM
american_scientific_journal-766	17	11	million	million	NUM
american_scientific_journal-766	17	12	people	people	NOUN
american_scientific_journal-766	17	13	worldwide	worldwide	ADV
american_scientific_journal-766	17	14	are	be	AUX
american_scientific_journal-766	17	15	affected	affect	VERB
american_scientific_journal-766	17	16	and	and	CCONJ
american_scientific_journal-766	17	17	>	>	SYM
american_scientific_journal-766	17	18	350000	350000	NUM
american_scientific_journal-766	17	19	individuals	individual	NOUN
american_scientific_journal-766	17	20	die	die	VERB
american_scientific_journal-766	17	21	due	due	ADJ
american_scientific_journal-766	17	22	to	to	ADP
american_scientific_journal-766	17	23	liver	liver	NOUN
american_scientific_journal-766	17	24	disease	disease	NOUN
american_scientific_journal-766	17	25	[	[	X
american_scientific_journal-766	17	26	2	2	NUM
american_scientific_journal-766	17	27	]	]	PUNCT
american_scientific_journal-766	17	28	.	.	PUNCT
american_scientific_journal-766	18	1	a	a	DET
american_scientific_journal-766	18	2	smaller	small	ADJ
american_scientific_journal-766	18	3	but	but	CCONJ
american_scientific_journal-766	18	4	significant	significant	ADJ
american_scientific_journal-766	18	5	number	number	NOUN
american_scientific_journal-766	18	6	of	of	ADP
american_scientific_journal-766	18	7	infected	infected	ADJ
american_scientific_journal-766	18	8	patients	patient	NOUN
american_scientific_journal-766	18	9	also	also	ADV
american_scientific_journal-766	18	10	show	show	VERB
american_scientific_journal-766	18	11	extrahepatic	extrahepatic	ADJ
american_scientific_journal-766	18	12	complications	complication	NOUN
american_scientific_journal-766	18	13	such	such	ADJ
american_scientific_journal-766	18	14	as	as	ADP
american_scientific_journal-766	18	15	mixed	mixed	ADJ
american_scientific_journal-766	18	16	cryoglobulinemia	cryoglobulinemia	NOUN
american_scientific_journal-766	18	17	,	,	PUNCT
american_scientific_journal-766	18	18	glomerulonephritis	glomerulonephritis	NOUN
american_scientific_journal-766	18	19	,	,	PUNCT
american_scientific_journal-766	18	20	arthritis	arthritis	NOUN
american_scientific_journal-766	18	21	,	,	PUNCT
american_scientific_journal-766	18	22	and	and	CCONJ
american_scientific_journal-766	18	23	some	some	DET
american_scientific_journal-766	18	24	varieties	variety	NOUN
american_scientific_journal-766	18	25	of	of	ADP
american_scientific_journal-766	18	26	b	b	NOUN
american_scientific_journal-766	18	27	-	-	PUNCT
american_scientific_journal-766	18	28	cell	cell	NOUN
american_scientific_journal-766	18	29	lymphoma	lymphoma	NOUN
american_scientific_journal-766	18	30	[	[	X
american_scientific_journal-766	18	31	3	3	NUM
american_scientific_journal-766	18	32	]	]	PUNCT
american_scientific_journal-766	18	33	.	.	PUNCT
american_scientific_journal-766	19	1	genotypes	genotype	NOUN
american_scientific_journal-766	19	2	1	1	NUM
american_scientific_journal-766	19	3	-	-	SYM
american_scientific_journal-766	19	4	3	3	NUM
american_scientific_journal-766	19	5	have	have	VERB
american_scientific_journal-766	19	6	a	a	DET
american_scientific_journal-766	19	7	worldwide	worldwide	ADJ
american_scientific_journal-766	19	8	distribution	distribution	NOUN
american_scientific_journal-766	19	9	with	with	ADP
american_scientific_journal-766	19	10	genotypes	genotype	NOUN
american_scientific_journal-766	19	11	1a	1a	PROPN
american_scientific_journal-766	19	12	and	and	CCONJ
american_scientific_journal-766	19	13	1b	1b	NUM
american_scientific_journal-766	19	14	accounting	account	VERB
american_scientific_journal-766	19	15	for	for	ADP
american_scientific_journal-766	19	16	nearly	nearly	ADV
american_scientific_journal-766	19	17	60	60	NUM
american_scientific_journal-766	19	18	%	%	NOUN
american_scientific_journal-766	19	19	of	of	ADP
american_scientific_journal-766	19	20	global	global	ADJ
american_scientific_journal-766	19	21	hepatitis	hepatitis	PROPN
american_scientific_journal-766	19	22	c	c	PROPN
american_scientific_journal-766	19	23	infections	infection	NOUN
american_scientific_journal-766	19	24	[	[	X
american_scientific_journal-766	19	25	4	4	NUM
american_scientific_journal-766	19	26	]	]	PUNCT
american_scientific_journal-766	19	27	.	.	PUNCT
american_scientific_journal-766	20	1	central	central	ADJ
american_scientific_journal-766	20	2	and	and	CCONJ
american_scientific_journal-766	20	3	east	east	PROPN
american_scientific_journal-766	20	4	asia	asia	PROPN
american_scientific_journal-766	20	5	and	and	CCONJ
american_scientific_journal-766	20	6	north	north	PROPN
american_scientific_journal-766	20	7	africa	africa	PROPN
american_scientific_journal-766	20	8	/	/	SYM
american_scientific_journal-766	20	9	middle	middle	PROPN
american_scientific_journal-766	20	10	east	east	PROPN
american_scientific_journal-766	20	11	are	be	AUX
american_scientific_journal-766	20	12	estimated	estimate	VERB
american_scientific_journal-766	20	13	to	to	PART
american_scientific_journal-766	20	14	have	have	VERB
american_scientific_journal-766	20	15	the	the	DET
american_scientific_journal-766	20	16	highest	high	ADJ
american_scientific_journal-766	20	17	prevalence	prevalence	NOUN
american_scientific_journal-766	20	18	of	of	ADP
american_scientific_journal-766	20	19	hepatitis	hepatitis	PROPN
american_scientific_journal-766	20	20	c	c	PROPN
american_scientific_journal-766	20	21	virus	virus	NOUN
american_scientific_journal-766	20	22	(	(	PUNCT
american_scientific_journal-766	20	23	hcv	hcv	NOUN
american_scientific_journal-766	20	24	)	)	PUNCT
american_scientific_journal-766	20	25	infection	infection	NOUN
american_scientific_journal-766	20	26	(	(	PUNCT
american_scientific_journal-766	20	27	>	>	SYM
american_scientific_journal-766	20	28	3.5	3.5	NUM
american_scientific_journal-766	20	29	%	%	NOUN
american_scientific_journal-766	20	30	)	)	PUNCT
american_scientific_journal-766	21	1	[	[	X
american_scientific_journal-766	21	2	5	5	NUM
american_scientific_journal-766	21	3	]	]	PUNCT
american_scientific_journal-766	21	4	.	.	PUNCT
american_scientific_journal-766	22	1	in	in	ADP
american_scientific_journal-766	22	2	usa	usa	PROPN
american_scientific_journal-766	22	3	,	,	PUNCT
american_scientific_journal-766	22	4	the	the	DET
american_scientific_journal-766	22	5	hcv	hcv	PROPN
american_scientific_journal-766	22	6	prevalence	prevalence	NOUN
american_scientific_journal-766	22	7	is	be	AUX
american_scientific_journal-766	22	8	estimated	estimate	VERB
american_scientific_journal-766	22	9	to	to	PART
american_scientific_journal-766	22	10	range	range	VERB
american_scientific_journal-766	22	11	between	between	ADP
american_scientific_journal-766	22	12	1.3	1.3	NUM
american_scientific_journal-766	22	13	%	%	NOUN
american_scientific_journal-766	22	14	and	and	CCONJ
american_scientific_journal-766	22	15	1.9	1.9	NUM
american_scientific_journal-766	22	16	%	%	NOUN
american_scientific_journal-766	23	1	[	[	X
american_scientific_journal-766	23	2	6	6	NUM
american_scientific_journal-766	23	3	]	]	PUNCT
american_scientific_journal-766	23	4	.	.	PUNCT
american_scientific_journal-766	24	1	in	in	ADP
american_scientific_journal-766	24	2	addition	addition	NOUN
american_scientific_journal-766	24	3	,	,	PUNCT
american_scientific_journal-766	24	4	untreated	untreated	ADJ
american_scientific_journal-766	24	5	chronic	chronic	ADJ
american_scientific_journal-766	24	6	hcv	hcv	NOUN
american_scientific_journal-766	24	7	infection	infection	NOUN
american_scientific_journal-766	24	8	imposes	impose	VERB
american_scientific_journal-766	24	9	a	a	DET
american_scientific_journal-766	24	10	considerable	considerable	ADJ
american_scientific_journal-766	24	11	financial	financial	ADJ
american_scientific_journal-766	24	12	burden	burden	NOUN
american_scientific_journal-766	24	13	with	with	ADP
american_scientific_journal-766	24	14	average	average	ADJ
american_scientific_journal-766	24	15	individual	individual	ADJ
american_scientific_journal-766	24	16	lifetime	lifetime	NOUN
american_scientific_journal-766	24	17	costs	cost	NOUN
american_scientific_journal-766	24	18	estimated	estimate	VERB
american_scientific_journal-766	24	19	at	at	ADP
american_scientific_journal-766	24	20	around	around	ADP
american_scientific_journal-766	24	21	$	$	SYM
american_scientific_journal-766	24	22	65,000	65,000	NUM
american_scientific_journal-766	24	23	us	us	PROPN
american_scientific_journal-766	24	24	dollars	dollar	NOUN
american_scientific_journal-766	24	25	and	and	CCONJ
american_scientific_journal-766	24	26	total	total	ADJ
american_scientific_journal-766	24	27	costs	cost	NOUN
american_scientific_journal-766	24	28	of	of	ADP
american_scientific_journal-766	24	29	approximately	approximately	ADV
american_scientific_journal-766	24	30	$	$	SYM
american_scientific_journal-766	24	31	6.5	6.5	NUM
american_scientific_journal-766	24	32	billion	billion	NUM
american_scientific_journal-766	24	33	us	us	PROPN
american_scientific_journal-766	24	34	dollars	dollar	NOUN
american_scientific_journal-766	25	1	[	[	X
american_scientific_journal-766	25	2	7	7	NUM
american_scientific_journal-766	25	3	]	]	PUNCT
american_scientific_journal-766	25	4	.	.	PUNCT
american_scientific_journal-766	26	1	in	in	ADP
american_scientific_journal-766	26	2	european	european	ADJ
american_scientific_journal-766	26	3	countries	country	NOUN
american_scientific_journal-766	26	4	,	,	PUNCT
american_scientific_journal-766	26	5	the	the	DET
american_scientific_journal-766	26	6	hcv	hcv	PROPN
american_scientific_journal-766	26	7	prevalence	prevalence	NOUN
american_scientific_journal-766	26	8	varies	vary	VERB
american_scientific_journal-766	26	9	from	from	ADP
american_scientific_journal-766	26	10	0.4	0.4	NUM
american_scientific_journal-766	26	11	%	%	NOUN
american_scientific_journal-766	26	12	in	in	ADP
american_scientific_journal-766	26	13	sweden	sweden	PROPN
american_scientific_journal-766	26	14	,	,	PUNCT
american_scientific_journal-766	26	15	germany	germany	PROPN
american_scientific_journal-766	26	16	and	and	CCONJ
american_scientific_journal-766	26	17	the	the	DET
american_scientific_journal-766	26	18	netherlands	netherlands	PROPN
american_scientific_journal-766	26	19	to	to	ADP
american_scientific_journal-766	26	20	over	over	ADP
american_scientific_journal-766	26	21	2%-3	2%-3	NUM
american_scientific_journal-766	26	22	%	%	NOUN
american_scientific_journal-766	26	23	in	in	ADP
american_scientific_journal-766	26	24	some	some	DET
american_scientific_journal-766	26	25	mediterranean	mediterranean	ADJ
american_scientific_journal-766	26	26	countries	country	NOUN
american_scientific_journal-766	26	27	and	and	CCONJ
american_scientific_journal-766	26	28	even	even	ADV
american_scientific_journal-766	26	29	over	over	ADP
american_scientific_journal-766	26	30	5	5	NUM
american_scientific_journal-766	26	31	%	%	NOUN
american_scientific_journal-766	26	32	in	in	ADP
american_scientific_journal-766	26	33	some	some	DET
american_scientific_journal-766	26	34	communities	community	NOUN
american_scientific_journal-766	26	35	in	in	ADP
american_scientific_journal-766	26	36	italy	italy	PROPN
american_scientific_journal-766	27	1	[	[	X
american_scientific_journal-766	27	2	8	8	NUM
american_scientific_journal-766	27	3	]	]	PUNCT
american_scientific_journal-766	27	4	.	.	PUNCT
american_scientific_journal-766	28	1	in	in	ADP
american_scientific_journal-766	28	2	egypt	egypt	PROPN
american_scientific_journal-766	28	3	,	,	PUNCT
american_scientific_journal-766	28	4	hcv	hcv	PROPN
american_scientific_journal-766	28	5	is	be	AUX
american_scientific_journal-766	28	6	considered	consider	VERB
american_scientific_journal-766	28	7	the	the	DET
american_scientific_journal-766	28	8	most	most	ADV
american_scientific_journal-766	28	9	common	common	ADJ
american_scientific_journal-766	28	10	etiology	etiology	NOUN
american_scientific_journal-766	28	11	of	of	ADP
american_scientific_journal-766	28	12	chronic	chronic	ADJ
american_scientific_journal-766	28	13	liver	liver	NOUN
american_scientific_journal-766	28	14	disease	disease	NOUN
american_scientific_journal-766	28	15	[	[	X
american_scientific_journal-766	28	16	9	9	NUM
american_scientific_journal-766	28	17	]	]	PUNCT
american_scientific_journal-766	28	18	.	.	PUNCT
american_scientific_journal-766	29	1	hcv	hcv	PROPN
american_scientific_journal-766	29	2	is	be	AUX
american_scientific_journal-766	29	3	classified	classify	VERB
american_scientific_journal-766	29	4	into	into	ADP
american_scientific_journal-766	29	5	6	6	NUM
american_scientific_journal-766	29	6	major	major	ADJ
american_scientific_journal-766	29	7	genotypes	genotype	NOUN
american_scientific_journal-766	29	8	.	.	PUNCT
american_scientific_journal-766	30	1	some	some	DET
american_scientific_journal-766	30	2	genotypes	genotype	NOUN
american_scientific_journal-766	30	3	have	have	VERB
american_scientific_journal-766	30	4	a	a	DET
american_scientific_journal-766	30	5	restricted	restricted	ADJ
american_scientific_journal-766	30	6	geographical	geographical	ADJ
american_scientific_journal-766	30	7	distribution	distribution	NOUN
american_scientific_journal-766	30	8	(	(	PUNCT
american_scientific_journal-766	30	9	genotypes	genotype	NOUN
american_scientific_journal-766	30	10	4	4	NUM
american_scientific_journal-766	30	11	-	-	SYM
american_scientific_journal-766	30	12	6	6	NUM
american_scientific_journal-766	30	13	)	)	PUNCT
american_scientific_journal-766	30	14	,	,	PUNCT
american_scientific_journal-766	30	15	while	while	SCONJ
american_scientific_journal-766	30	16	others	other	NOUN
american_scientific_journal-766	30	17	(	(	PUNCT
american_scientific_journal-766	30	18	genotypes	genotype	NOUN
american_scientific_journal-766	30	19	1	1	NUM
american_scientific_journal-766	30	20	-	-	SYM
american_scientific_journal-766	30	21	3	3	NUM
american_scientific_journal-766	30	22	)	)	PUNCT
american_scientific_journal-766	30	23	are	be	AUX
american_scientific_journal-766	30	24	more	more	ADV
american_scientific_journal-766	30	25	broadly	broadly	ADV
american_scientific_journal-766	30	26	disseminated	disseminate	VERB
american_scientific_journal-766	30	27	.	.	PUNCT
american_scientific_journal-766	31	1	genotype	genotype	NOUN
american_scientific_journal-766	31	2	1	1	NUM
american_scientific_journal-766	31	3	(	(	PUNCT
american_scientific_journal-766	31	4	subtypes	subtype	NOUN
american_scientific_journal-766	31	5	1a	1a	NOUN
american_scientific_journal-766	31	6	and	and	CCONJ
american_scientific_journal-766	31	7	1b	1b	NUM
american_scientific_journal-766	31	8	)	)	PUNCT
american_scientific_journal-766	31	9	is	be	AUX
american_scientific_journal-766	31	10	the	the	DET
american_scientific_journal-766	31	11	most	most	ADV
american_scientific_journal-766	31	12	prevalent	prevalent	ADJ
american_scientific_journal-766	31	13	genotype	genotype	NOUN
american_scientific_journal-766	31	14	in	in	ADP
american_scientific_journal-766	31	15	the	the	DET
american_scientific_journal-766	31	16	world	world	NOUN
american_scientific_journal-766	31	17	.	.	PUNCT
american_scientific_journal-766	32	1	genotype	genotype	NOUN
american_scientific_journal-766	32	2	2	2	NUM
american_scientific_journal-766	32	3	is	be	AUX
american_scientific_journal-766	32	4	found	find	VERB
american_scientific_journal-766	32	5	in	in	ADP
american_scientific_journal-766	32	6	clusters	cluster	NOUN
american_scientific_journal-766	32	7	in	in	ADP
american_scientific_journal-766	32	8	the	the	DET
american_scientific_journal-766	32	9	mediterranean	mediterranean	PROPN
american_scientific_journal-766	32	10	region	region	NOUN
american_scientific_journal-766	32	11	,	,	PUNCT
american_scientific_journal-766	32	12	genotype	genotype	NOUN
american_scientific_journal-766	32	13	3	3	NUM
american_scientific_journal-766	32	14	is	be	AUX
american_scientific_journal-766	32	15	most	most	ADV
american_scientific_journal-766	32	16	prevalent	prevalent	ADJ
american_scientific_journal-766	32	17	among	among	ADP
american_scientific_journal-766	32	18	intravenous	intravenous	ADJ
american_scientific_journal-766	32	19	drug	drug	NOUN
american_scientific_journal-766	32	20	users	user	NOUN
american_scientific_journal-766	32	21	and	and	CCONJ
american_scientific_journal-766	32	22	genotype	genotype	NOUN
american_scientific_journal-766	32	23	4	4	NUM
american_scientific_journal-766	32	24	is	be	AUX
american_scientific_journal-766	32	25	found	find	VERB
american_scientific_journal-766	32	26	mostly	mostly	ADV
american_scientific_journal-766	32	27	in	in	ADP
american_scientific_journal-766	32	28	egypt	egypt	PROPN
american_scientific_journal-766	32	29	,	,	PUNCT
american_scientific_journal-766	32	30	while	while	SCONJ
american_scientific_journal-766	32	31	genotypes	genotype	NOUN
american_scientific_journal-766	32	32	5	5	NUM
american_scientific_journal-766	32	33	and	and	CCONJ
american_scientific_journal-766	32	34	6	6	NUM
american_scientific_journal-766	32	35	are	be	AUX
american_scientific_journal-766	32	36	less	less	ADV
american_scientific_journal-766	32	37	frequent	frequent	ADJ
american_scientific_journal-766	33	1	[	[	X
american_scientific_journal-766	33	2	10].the	10].the	NUM
american_scientific_journal-766	33	3	clinical	clinical	ADJ
american_scientific_journal-766	33	4	presentation	presentation	NOUN
american_scientific_journal-766	33	5	and	and	CCONJ
american_scientific_journal-766	33	6	management	management	NOUN
american_scientific_journal-766	33	7	of	of	ADP
american_scientific_journal-766	33	8	infection	infection	NOUN
american_scientific_journal-766	33	9	arising	arise	VERB
american_scientific_journal-766	33	10	from	from	ADP
american_scientific_journal-766	33	11	viral	viral	ADJ
american_scientific_journal-766	33	12	genotypes	genotype	NOUN
american_scientific_journal-766	33	13	has	have	AUX
american_scientific_journal-766	33	14	advanced	advance	VERB
american_scientific_journal-766	33	15	rapidly	rapidly	ADV
american_scientific_journal-766	33	16	.	.	PUNCT
american_scientific_journal-766	34	1	in	in	ADP
american_scientific_journal-766	34	2	contrast	contrast	NOUN
american_scientific_journal-766	34	3	,	,	PUNCT
american_scientific_journal-766	34	4	genotype	genotype	NOUN
american_scientific_journal-766	34	5	4	4	NUM
american_scientific_journal-766	34	6	,	,	PUNCT
american_scientific_journal-766	34	7	5	5	NUM
american_scientific_journal-766	34	8	and	and	CCONJ
american_scientific_journal-766	34	9	6	6	NUM
american_scientific_journal-766	34	10	have	have	AUX
american_scientific_journal-766	34	11	not	not	PART
american_scientific_journal-766	34	12	been	be	AUX
american_scientific_journal-766	34	13	adequately	adequately	ADV
american_scientific_journal-766	34	14	studied	study	VERB
american_scientific_journal-766	34	15	,	,	PUNCT
american_scientific_journal-766	34	16	therefore	therefore	ADV
american_scientific_journal-766	34	17	,	,	PUNCT
american_scientific_journal-766	34	18	the	the	DET
american_scientific_journal-766	34	19	management	management	NOUN
american_scientific_journal-766	34	20	strategies	strategy	NOUN
american_scientific_journal-766	34	21	for	for	ADP
american_scientific_journal-766	34	22	patients	patient	NOUN
american_scientific_journal-766	34	23	infected	infect	VERB
american_scientific_journal-766	34	24	with	with	ADP
american_scientific_journal-766	34	25	these	these	DET
american_scientific_journal-766	34	26	genotypes	genotype	NOUN
american_scientific_journal-766	34	27	are	be	AUX
american_scientific_journal-766	34	28	not	not	PART
american_scientific_journal-766	34	29	as	as	ADV
american_scientific_journal-766	34	30	well	well	ADV
american_scientific_journal-766	34	31	developed	develop	VERB
american_scientific_journal-766	34	32	[	[	PUNCT
american_scientific_journal-766	34	33	11	11	NUM
american_scientific_journal-766	34	34	]	]	PUNCT
american_scientific_journal-766	34	35	.	.	PUNCT
american_scientific_journal-766	35	1	hcv	hcv	PROPN
american_scientific_journal-766	35	2	is	be	AUX
american_scientific_journal-766	35	3	a	a	DET
american_scientific_journal-766	35	4	small	small	ADJ
american_scientific_journal-766	35	5	,	,	PUNCT
american_scientific_journal-766	35	6	9,500nucleotide	9,500nucleotide	INTJ
american_scientific_journal-766	35	7	,	,	PUNCT
american_scientific_journal-766	35	8	plusstrand	plusstrand	ADJ
american_scientific_journal-766	35	9	ribonucleic	ribonucleic	NOUN
american_scientific_journal-766	35	10	acid	acid	NOUN
american_scientific_journal-766	35	11	(	(	PUNCT
american_scientific_journal-766	35	12	rna	rna	PROPN
american_scientific_journal-766	35	13	)	)	PUNCT
american_scientific_journal-766	35	14	virus	virus	NOUN
american_scientific_journal-766	35	15	that	that	PRON
american_scientific_journal-766	35	16	replicates	replicate	VERB
american_scientific_journal-766	35	17	in	in	ADP
american_scientific_journal-766	35	18	the	the	DET
american_scientific_journal-766	35	19	cytoplasm	cytoplasm	NOUN
american_scientific_journal-766	35	20	with	with	ADP
american_scientific_journal-766	35	21	a	a	DET
american_scientific_journal-766	35	22	single	single	ADJ
american_scientific_journal-766	35	23	open	open	ADJ
american_scientific_journal-766	35	24	–	–	PUNCT
american_scientific_journal-766	35	25	reading	read	VERB
american_scientific_journal-766	35	26	frame	frame	NOUN
american_scientific_journal-766	36	1	[	[	X
american_scientific_journal-766	36	2	12	12	NUM
american_scientific_journal-766	36	3	]	]	PUNCT
american_scientific_journal-766	36	4	.	.	PUNCT
american_scientific_journal-766	37	1	similar	similar	ADJ
american_scientific_journal-766	37	2	to	to	ADP
american_scientific_journal-766	37	3	other	other	ADJ
american_scientific_journal-766	37	4	positive	positive	ADJ
american_scientific_journal-766	37	5	–	–	PUNCT
american_scientific_journal-766	37	6	strand	strand	NOUN
american_scientific_journal-766	37	7	rna	rna	NOUN
american_scientific_journal-766	37	8	viruses	virus	NOUN
american_scientific_journal-766	37	9	,	,	PUNCT
american_scientific_journal-766	37	10	the	the	DET
american_scientific_journal-766	37	11	genomic	genomic	ADJ
american_scientific_journal-766	37	12	rna	rna	NOUN
american_scientific_journal-766	37	13	of	of	ADP
american_scientific_journal-766	37	14	hcv	hcv	PROPN
american_scientific_journal-766	37	15	serves	serve	VERB
american_scientific_journal-766	37	16	as	as	ADP
american_scientific_journal-766	37	17	messenger	messenger	PROPN
american_scientific_journal-766	37	18	rna	rna	PROPN
american_scientific_journal-766	37	19	(	(	PUNCT
american_scientific_journal-766	37	20	mrna	mrna	PROPN
american_scientific_journal-766	37	21	)	)	PUNCT
american_scientific_journal-766	37	22	for	for	ADP
american_scientific_journal-766	37	23	the	the	DET
american_scientific_journal-766	37	24	translation	translation	NOUN
american_scientific_journal-766	37	25	of	of	ADP
american_scientific_journal-766	37	26	viral	viral	ADJ
american_scientific_journal-766	37	27	proteins	protein	NOUN
american_scientific_journal-766	37	28	.	.	PUNCT
american_scientific_journal-766	38	1	hcv	hcv	NOUN
american_scientific_journal-766	38	2	encodes	encode	NOUN
american_scientific_journal-766	38	3	a	a	DET
american_scientific_journal-766	38	4	polyprotein	polyprotein	NOUN
american_scientific_journal-766	38	5	of	of	ADP
american_scientific_journal-766	38	6	∼3,000	∼3,000	ADJ
american_scientific_journal-766	38	7	amino	amino	ADJ
american_scientific_journal-766	38	8	acids	acid	NOUN
american_scientific_journal-766	38	9	that	that	PRON
american_scientific_journal-766	38	10	is	be	AUX
american_scientific_journal-766	38	11	cleaved	cleave	VERB
american_scientific_journal-766	38	12	into	into	ADP
american_scientific_journal-766	38	13	at	at	ADV
american_scientific_journal-766	38	14	least	least	ADV
american_scientific_journal-766	38	15	10	10	NUM
american_scientific_journal-766	38	16	mature	mature	ADJ
american_scientific_journal-766	38	17	proteins	protein	NOUN
american_scientific_journal-766	38	18	by	by	ADP
american_scientific_journal-766	38	19	cellular	cellular	ADJ
american_scientific_journal-766	38	20	and	and	CCONJ
american_scientific_journal-766	38	21	viral	viral	ADJ
american_scientific_journal-766	38	22	proteases	protease	NOUN
american_scientific_journal-766	38	23	[	[	X
american_scientific_journal-766	38	24	13	13	NUM
american_scientific_journal-766	38	25	]	]	PUNCT
american_scientific_journal-766	38	26	.	.	PUNCT
american_scientific_journal-766	39	1	during	during	ADP
american_scientific_journal-766	39	2	viral	viral	ADJ
american_scientific_journal-766	39	3	replication	replication	NOUN
american_scientific_journal-766	39	4	the	the	DET
american_scientific_journal-766	39	5	poly	poly	ADJ
american_scientific_journal-766	39	6	protein	protein	NOUN
american_scientific_journal-766	39	7	is	be	AUX
american_scientific_journal-766	39	8	cleaved	cleave	VERB
american_scientific_journal-766	39	9	by	by	ADP
american_scientific_journal-766	39	10	viral	viral	ADJ
american_scientific_journal-766	39	11	as	as	ADV
american_scientific_journal-766	39	12	well	well	ADV
american_scientific_journal-766	39	13	host	host	NOUN
american_scientific_journal-766	39	14	enzymes	enzyme	NOUN
american_scientific_journal-766	39	15	into	into	ADP
american_scientific_journal-766	39	16	three	three	NUM
american_scientific_journal-766	39	17	structural	structural	ADJ
american_scientific_journal-766	39	18	proteins	protein	NOUN
american_scientific_journal-766	39	19	(	(	PUNCT
american_scientific_journal-766	39	20	core	core	NOUN
american_scientific_journal-766	39	21	,	,	PUNCT
american_scientific_journal-766	39	22	e1	e1	PROPN
american_scientific_journal-766	39	23	,	,	PUNCT
american_scientific_journal-766	39	24	e	e	NOUN
american_scientific_journal-766	39	25	2	2	NUM
american_scientific_journal-766	39	26	)	)	PUNCT
american_scientific_journal-766	39	27	and	and	CCONJ
american_scientific_journal-766	39	28	seven	seven	NUM
american_scientific_journal-766	39	29	non	non	ADJ
american_scientific_journal-766	39	30	-	-	ADJ
american_scientific_journal-766	39	31	structural	structural	ADJ
american_scientific_journal-766	39	32	proteins	protein	NOUN
american_scientific_journal-766	39	33	(	(	PUNCT
american_scientific_journal-766	39	34	p7	p7	ADJ
american_scientific_journal-766	39	35	,	,	PUNCT
american_scientific_journal-766	39	36	ns3	ns3	NOUN
american_scientific_journal-766	39	37	,	,	PUNCT
american_scientific_journal-766	39	38	ns4a	ns4a	NOUN
american_scientific_journal-766	39	39	,	,	PUNCT
american_scientific_journal-766	39	40	ns4b	ns4b	NOUN
american_scientific_journal-766	39	41	,	,	PUNCT
american_scientific_journal-766	39	42	ns5a	ns5a	NOUN
american_scientific_journal-766	39	43	,	,	PUNCT
american_scientific_journal-766	39	44	and	and	CCONJ
american_scientific_journal-766	39	45	ns5b	ns5b	PROPN
american_scientific_journal-766	39	46	)	)	PUNCT
american_scientific_journal-766	40	1	[	[	X
american_scientific_journal-766	40	2	14].once	14].once	PROPN
american_scientific_journal-766	40	3	the	the	DET
american_scientific_journal-766	40	4	virus	virus	NOUN
american_scientific_journal-766	40	5	is	be	AUX
american_scientific_journal-766	40	6	released	release	VERB
american_scientific_journal-766	40	7	into	into	ADP
american_scientific_journal-766	40	8	the	the	DET
american_scientific_journal-766	40	9	cell	cell	NOUN
american_scientific_journal-766	40	10	,	,	PUNCT
american_scientific_journal-766	40	11	the	the	DET
american_scientific_journal-766	40	12	viral	viral	ADJ
american_scientific_journal-766	40	13	polyprotein	polyprotein	NOUN
american_scientific_journal-766	40	14	is	be	AUX
american_scientific_journal-766	40	15	translated	translate	VERB
american_scientific_journal-766	40	16	and	and	CCONJ
american_scientific_journal-766	40	17	cleaved	cleave	VERB
american_scientific_journal-766	40	18	by	by	ADP
american_scientific_journal-766	40	19	host	host	NOUN
american_scientific_journal-766	40	20	proteases	protease	NOUN
american_scientific_journal-766	40	21	and	and	CCONJ
american_scientific_journal-766	40	22	the	the	DET
american_scientific_journal-766	40	23	viral	viral	ADJ
american_scientific_journal-766	40	24	ns3	ns3	NOUN
american_scientific_journal-766	40	25	-	-	PUNCT
american_scientific_journal-766	40	26	4a	4a	NOUN
american_scientific_journal-766	40	27	protease	protease	NOUN
american_scientific_journal-766	40	28	into	into	ADP
american_scientific_journal-766	40	29	ten	ten	NUM
american_scientific_journal-766	40	30	mature	mature	ADJ
american_scientific_journal-766	40	31	proteins	protein	NOUN
american_scientific_journal-766	40	32	.	.	PUNCT
american_scientific_journal-766	41	1	next	next	ADJ
american_scientific_journal-766	41	2	,	,	PUNCT
american_scientific_journal-766	41	3	viral	viral	ADJ
american_scientific_journal-766	41	4	rna	rna	NOUN
american_scientific_journal-766	41	5	is	be	AUX
american_scientific_journal-766	41	6	replicated	replicate	VERB
american_scientific_journal-766	41	7	into	into	ADP
american_scientific_journal-766	41	8	progeny	progeny	ADJ
american_scientific_journal-766	41	9	rna	rna	NOUN
american_scientific_journal-766	41	10	by	by	ADP
american_scientific_journal-766	41	11	the	the	DET
american_scientific_journal-766	41	12	viral	viral	ADJ
american_scientific_journal-766	41	13	ns5b	ns5b	ADJ
american_scientific_journal-766	41	14	polymerase	polymerase	NOUN
american_scientific_journal-766	42	1	[	[	X
american_scientific_journal-766	42	2	15	15	NUM
american_scientific_journal-766	42	3	]	]	PUNCT
american_scientific_journal-766	42	4	.	.	PUNCT
american_scientific_journal-766	43	1	the	the	DET
american_scientific_journal-766	43	2	c	c	NOUN
american_scientific_journal-766	43	3	-	-	PUNCT
american_scientific_journal-766	43	4	terminal	terminal	ADJ
american_scientific_journal-766	43	5	component	component	NOUN
american_scientific_journal-766	43	6	of	of	ADP
american_scientific_journal-766	43	7	the	the	DET
american_scientific_journal-766	43	8	polyprotein	polyprotein	NOUN
american_scientific_journal-766	43	9	contains	contain	VERB
american_scientific_journal-766	43	10	the	the	DET
american_scientific_journal-766	43	11	non	non	ADJ
american_scientific_journal-766	43	12	-	-	ADJ
american_scientific_journal-766	43	13	structural	structural	ADJ
american_scientific_journal-766	43	14	proteins	protein	NOUN
american_scientific_journal-766	43	15	(	(	PUNCT
american_scientific_journal-766	43	16	ns2	ns2	NOUN
american_scientific_journal-766	43	17	,	,	PUNCT
american_scientific_journal-766	43	18	ns3	ns3	NOUN
american_scientific_journal-766	43	19	,	,	PUNCT
american_scientific_journal-766	43	20	ns4a	ns4a	NOUN
american_scientific_journal-766	43	21	,	,	PUNCT
american_scientific_journal-766	43	22	ns4b	ns4b	NOUN
american_scientific_journal-766	43	23	,	,	PUNCT
american_scientific_journal-766	43	24	ns5a	ns5a	NOUN
american_scientific_journal-766	43	25	and	and	CCONJ
american_scientific_journal-766	43	26	ns5b	ns5b	PROPN
american_scientific_journal-766	43	27	)	)	PUNCT
american_scientific_journal-766	43	28	.	.	PUNCT
american_scientific_journal-766	44	1	ns2	ns2	NOUN
american_scientific_journal-766	44	2	and	and	CCONJ
american_scientific_journal-766	44	3	ns3	ns3	NOUN
american_scientific_journal-766	44	4	are	be	AUX
american_scientific_journal-766	44	5	viral	viral	ADJ
american_scientific_journal-766	44	6	proteases	protease	NOUN
american_scientific_journal-766	44	7	required	require	VERB
american_scientific_journal-766	44	8	for	for	ADP
american_scientific_journal-766	44	9	the	the	DET
american_scientific_journal-766	44	10	processing	processing	NOUN
american_scientific_journal-766	44	11	of	of	ADP
american_scientific_journal-766	44	12	the	the	DET
american_scientific_journal-766	44	13	hcv	hcv	ADJ
american_scientific_journal-766	44	14	non	non	ADJ
american_scientific_journal-766	44	15	-	-	ADJ
american_scientific_journal-766	44	16	structural	structural	ADJ
american_scientific_journal-766	44	17	portion	portion	NOUN
american_scientific_journal-766	44	18	of	of	ADP
american_scientific_journal-766	44	19	the	the	DET
american_scientific_journal-766	44	20	polyprotein	polyprotein	NOUN
american_scientific_journal-766	44	21	[	[	X
american_scientific_journal-766	44	22	16	16	NUM
american_scientific_journal-766	44	23	]	]	PUNCT
american_scientific_journal-766	44	24	.	.	PUNCT
american_scientific_journal-766	45	1	ns3	ns3	PROPN
american_scientific_journal-766	45	2	is	be	AUX
american_scientific_journal-766	45	3	a	a	DET
american_scientific_journal-766	45	4	multifunctional	multifunctional	ADJ
american_scientific_journal-766	45	5	enzyme	enzyme	NOUN
american_scientific_journal-766	45	6	,	,	PUNCT
american_scientific_journal-766	45	7	with	with	ADP
american_scientific_journal-766	45	8	serine	serine	NOUN
american_scientific_journal-766	45	9	protease	protease	NOUN
american_scientific_journal-766	45	10	,	,	PUNCT
american_scientific_journal-766	45	11	helicase	helicase	NOUN
american_scientific_journal-766	45	12	and	and	CCONJ
american_scientific_journal-766	45	13	nucleotide	nucleotide	NOUN
american_scientific_journal-766	45	14	triphosphatase	triphosphatase	NOUN
american_scientific_journal-766	45	15	activities	activity	NOUN
american_scientific_journal-766	45	16	,	,	PUNCT
american_scientific_journal-766	45	17	that	that	PRON
american_scientific_journal-766	45	18	forms	form	VERB
american_scientific_journal-766	45	19	a	a	DET
american_scientific_journal-766	45	20	stable	stable	ADJ
american_scientific_journal-766	45	21	heterodimeric	heterodimeric	ADJ
american_scientific_journal-766	45	22	complex	complex	NOUN
american_scientific_journal-766	45	23	with	with	ADP
american_scientific_journal-766	45	24	its	its	PRON
american_scientific_journal-766	45	25	ns4a	ns4a	NOUN
american_scientific_journal-766	45	26	cofactor	cofactor	NOUN
american_scientific_journal-766	45	27	,	,	PUNCT
american_scientific_journal-766	45	28	essential	essential	ADJ
american_scientific_journal-766	45	29	for	for	ADP
american_scientific_journal-766	45	30	protein	protein	NOUN
american_scientific_journal-766	45	31	folding	folding	NOUN
american_scientific_journal-766	45	32	and	and	CCONJ
american_scientific_journal-766	45	33	stabilization	stabilization	NOUN
american_scientific_journal-766	45	34	.	.	PUNCT
american_scientific_journal-766	46	1	moreover	moreover	ADV
american_scientific_journal-766	46	2	,	,	PUNCT
american_scientific_journal-766	46	3	the	the	DET
american_scientific_journal-766	46	4	ns3a	ns3a	PROPN
american_scientific_journal-766	46	5	/	/	SYM
american_scientific_journal-766	46	6	ns4a	ns4a	NOUN
american_scientific_journal-766	46	7	complex	complex	NOUN
american_scientific_journal-766	46	8	cleaves	cleave	VERB
american_scientific_journal-766	46	9	the	the	DET
american_scientific_journal-766	46	10	junctions	junction	NOUN
american_scientific_journal-766	46	11	between	between	ADP
american_scientific_journal-766	46	12	ns3/4a	ns3/4a	NOUN
american_scientific_journal-766	46	13	,	,	PUNCT
american_scientific_journal-766	46	14	ns4a	ns4a	NOUN
american_scientific_journal-766	46	15	/	/	SYM
american_scientific_journal-766	46	16	ns4b	ns4b	NOUN
american_scientific_journal-766	46	17	,	,	PUNCT
american_scientific_journal-766	46	18	ns4b	ns4b	NOUN
american_scientific_journal-766	46	19	/	/	SYM
american_scientific_journal-766	46	20	ns5a	ns5a	NOUN
american_scientific_journal-766	46	21	and	and	CCONJ
american_scientific_journal-766	46	22	ns5a	ns5a	PROPN
american_scientific_journal-766	46	23	/	/	SYM
american_scientific_journal-766	46	24	ns5b	ns5b	PROPN
american_scientific_journal-766	46	25	.	.	PUNCT
american_scientific_journal-766	47	1	ns3	ns3	PROPN
american_scientific_journal-766	47	2	has	have	AUX
american_scientific_journal-766	47	3	also	also	ADV
american_scientific_journal-766	47	4	helicase	helicase	NOUN
american_scientific_journal-766	47	5	activity	activity	NOUN
american_scientific_journal-766	47	6	necessary	necessary	ADJ
american_scientific_journal-766	47	7	for	for	ADP
american_scientific_journal-766	47	8	the	the	DET
american_scientific_journal-766	47	9	unwinding	unwinding	NOUN
american_scientific_journal-766	47	10	of	of	ADP
american_scientific_journal-766	47	11	the	the	DET
american_scientific_journal-766	47	12	2	2	NUM
american_scientific_journal-766	47	13	american	american	ADJ
american_scientific_journal-766	47	14	scientific	scientific	ADJ
american_scientific_journal-766	47	15	research	research	NOUN
american_scientific_journal-766	47	16	journal	journal	NOUN
american_scientific_journal-766	47	17	for	for	ADP
american_scientific_journal-766	47	18	engineering	engineering	NOUN
american_scientific_journal-766	47	19	,	,	PUNCT
american_scientific_journal-766	47	20	technology	technology	NOUN
american_scientific_journal-766	47	21	,	,	PUNCT
american_scientific_journal-766	47	22	and	and	CCONJ
american_scientific_journal-766	47	23	sciences	science	NOUN
american_scientific_journal-766	47	24	(	(	PUNCT
american_scientific_journal-766	47	25	asrjets	asrjet	NOUN
american_scientific_journal-766	47	26	)	)	PUNCT
american_scientific_journal-766	47	27	(	(	PUNCT
american_scientific_journal-766	47	28	2015	2015	NUM
american_scientific_journal-766	47	29	)	)	PUNCT
american_scientific_journal-766	47	30	volume	volume	NOUN
american_scientific_journal-766	47	31	13	13	NUM
american_scientific_journal-766	47	32	,	,	PUNCT
american_scientific_journal-766	47	33	no	no	DET
american_scientific_journal-766	47	34	1	1	NUM
american_scientific_journal-766	47	35	,	,	PUNCT
american_scientific_journal-766	47	36	pp	pp	ADV
american_scientific_journal-766	47	37	1	1	NUM
american_scientific_journal-766	47	38	-	-	SYM
american_scientific_journal-766	47	39	23	23	NUM
american_scientific_journal-766	47	40	hcv	hcv	NOUN
american_scientific_journal-766	47	41	genome	genome	NOUN
american_scientific_journal-766	47	42	during	during	ADP
american_scientific_journal-766	47	43	replication	replication	NOUN
american_scientific_journal-766	47	44	of	of	ADP
american_scientific_journal-766	47	45	the	the	DET
american_scientific_journal-766	47	46	rna	rna	NOUN
american_scientific_journal-766	47	47	[	[	X
american_scientific_journal-766	47	48	17	17	NUM
american_scientific_journal-766	47	49	]	]	PUNCT
american_scientific_journal-766	47	50	.	.	PUNCT
american_scientific_journal-766	48	1	ns4b	ns4b	NOUN
american_scientific_journal-766	48	2	,	,	PUNCT
american_scientific_journal-766	48	3	a	a	DET
american_scientific_journal-766	48	4	hydrophobic	hydrophobic	NOUN
american_scientific_journal-766	48	5	transmembrane	transmembrane	NOUN
american_scientific_journal-766	48	6	protein	protein	NOUN
american_scientific_journal-766	48	7	,	,	PUNCT
american_scientific_journal-766	48	8	is	be	AUX
american_scientific_journal-766	48	9	the	the	DET
american_scientific_journal-766	48	10	presumed	presume	VERB
american_scientific_journal-766	48	11	central	central	ADJ
american_scientific_journal-766	48	12	organizer	organizer	NOUN
american_scientific_journal-766	48	13	of	of	ADP
american_scientific_journal-766	48	14	the	the	DET
american_scientific_journal-766	48	15	hcv	hcv	PROPN
american_scientific_journal-766	48	16	replicase	replicase	NOUN
american_scientific_journal-766	48	17	complex	complex	NOUN
american_scientific_journal-766	48	18	and	and	CCONJ
american_scientific_journal-766	48	19	a	a	DET
american_scientific_journal-766	48	20	main	main	ADJ
american_scientific_journal-766	48	21	inducer	inducer	NOUN
american_scientific_journal-766	48	22	of	of	ADP
american_scientific_journal-766	48	23	intracellular	intracellular	ADJ
american_scientific_journal-766	48	24	membrane	membrane	NOUN
american_scientific_journal-766	48	25	rearrangements	rearrangement	NOUN
american_scientific_journal-766	48	26	that	that	PRON
american_scientific_journal-766	48	27	constitute	constitute	VERB
american_scientific_journal-766	48	28	the	the	DET
american_scientific_journal-766	48	29	membraneous	membraneous	ADJ
american_scientific_journal-766	48	30	web	web	NOUN
american_scientific_journal-766	48	31	.	.	PUNCT
american_scientific_journal-766	48	32	additionally	additionally	ADV
american_scientific_journal-766	48	33	,	,	PUNCT
american_scientific_journal-766	48	34	ns5a	ns5a	PROPN
american_scientific_journal-766	48	35	is	be	AUX
american_scientific_journal-766	48	36	an	an	DET
american_scientific_journal-766	48	37	rna	rna	NOUN
american_scientific_journal-766	48	38	-	-	PUNCT
american_scientific_journal-766	48	39	binding	bind	VERB
american_scientific_journal-766	48	40	phosphoprotein	phosphoprotein	NOUN
american_scientific_journal-766	48	41	required	require	VERB
american_scientific_journal-766	48	42	for	for	ADP
american_scientific_journal-766	48	43	rna	rna	NOUN
american_scientific_journal-766	48	44	replication	replication	NOUN
american_scientific_journal-766	48	45	and	and	CCONJ
american_scientific_journal-766	48	46	assembly	assembly	NOUN
american_scientific_journal-766	48	47	of	of	ADP
american_scientific_journal-766	48	48	infectious	infectious	ADJ
american_scientific_journal-766	48	49	virus	virus	NOUN
american_scientific_journal-766	48	50	particles	particle	NOUN
american_scientific_journal-766	48	51	whilst	whilst	SCONJ
american_scientific_journal-766	48	52	ns5b	ns5b	PROPN
american_scientific_journal-766	48	53	is	be	AUX
american_scientific_journal-766	48	54	the	the	DET
american_scientific_journal-766	48	55	rna	rna	NOUN
american_scientific_journal-766	48	56	-	-	PUNCT
american_scientific_journal-766	48	57	dependent	dependent	ADJ
american_scientific_journal-766	48	58	rna	rna	NOUN
american_scientific_journal-766	48	59	-	-	PUNCT
american_scientific_journal-766	48	60	polymerase	polymerase	NOUN
american_scientific_journal-766	48	61	required	require	VERB
american_scientific_journal-766	48	62	for	for	ADP
american_scientific_journal-766	48	63	viral	viral	ADJ
american_scientific_journal-766	48	64	replication	replication	NOUN
american_scientific_journal-766	48	65	.	.	PUNCT
american_scientific_journal-766	49	1	the	the	DET
american_scientific_journal-766	49	2	nonstructural	nonstructural	ADJ
american_scientific_journal-766	49	3	proteins	protein	NOUN
american_scientific_journal-766	49	4	mentioned	mention	VERB
american_scientific_journal-766	49	5	above	above	ADV
american_scientific_journal-766	49	6	have	have	AUX
american_scientific_journal-766	49	7	been	be	AUX
american_scientific_journal-766	49	8	the	the	DET
american_scientific_journal-766	49	9	target	target	NOUN
american_scientific_journal-766	49	10	for	for	ADP
american_scientific_journal-766	49	11	daas	daas	NOUN
american_scientific_journal-766	49	12	or	or	CCONJ
american_scientific_journal-766	49	13	specifically	specifically	ADV
american_scientific_journal-766	49	14	targeted	target	VERB
american_scientific_journal-766	49	15	antiviral	antiviral	ADJ
american_scientific_journal-766	49	16	therapy	therapy	NOUN
american_scientific_journal-766	49	17	for	for	ADP
american_scientific_journal-766	49	18	hepatitis	hepatitis	PROPN
american_scientific_journal-766	49	19	c	c	PROPN
american_scientific_journal-766	49	20	(	(	PUNCT
american_scientific_journal-766	49	21	stat	stat	PROPN
american_scientific_journal-766	49	22	-	-	PUNCT
american_scientific_journal-766	49	23	c	c	NOUN
american_scientific_journal-766	49	24	)	)	PUNCT
american_scientific_journal-766	50	1	[	[	X
american_scientific_journal-766	50	2	18	18	NUM
american_scientific_journal-766	50	3	]	]	PUNCT
american_scientific_journal-766	50	4	.	.	PUNCT
american_scientific_journal-766	51	1	2	2	X
american_scientific_journal-766	51	2	.	.	X
american_scientific_journal-766	51	3	current	current	ADJ
american_scientific_journal-766	51	4	treatment	treatment	NOUN
american_scientific_journal-766	51	5	regimens	regimen	NOUN
american_scientific_journal-766	51	6	available	available	ADJ
american_scientific_journal-766	51	7	for	for	ADP
american_scientific_journal-766	51	8	hcv	hcv	VERB
american_scientific_journal-766	51	9	the	the	DET
american_scientific_journal-766	51	10	goal	goal	NOUN
american_scientific_journal-766	51	11	of	of	ADP
american_scientific_journal-766	51	12	hcv	hcv	NOUN
american_scientific_journal-766	51	13	treatment	treatment	NOUN
american_scientific_journal-766	51	14	is	be	AUX
american_scientific_journal-766	51	15	to	to	PART
american_scientific_journal-766	51	16	achieve	achieve	VERB
american_scientific_journal-766	51	17	sustained	sustain	VERB
american_scientific_journal-766	51	18	virological	virological	ADJ
american_scientific_journal-766	51	19	response	response	NOUN
american_scientific_journal-766	51	20	(	(	PUNCT
american_scientific_journal-766	51	21	svr	svr	PROPN
american_scientific_journal-766	51	22	)	)	PUNCT
american_scientific_journal-766	51	23	defined	define	VERB
american_scientific_journal-766	51	24	as	as	ADP
american_scientific_journal-766	51	25	undetectable	undetectable	ADJ
american_scientific_journal-766	51	26	hcv	hcv	X
american_scientific_journal-766	51	27	rna	rna	NOUN
american_scientific_journal-766	51	28	at	at	ADP
american_scientific_journal-766	51	29	24	24	NUM
american_scientific_journal-766	51	30	weeks	week	NOUN
american_scientific_journal-766	51	31	or	or	CCONJ
american_scientific_journal-766	51	32	recently	recently	ADV
american_scientific_journal-766	51	33	at	at	ADP
american_scientific_journal-766	51	34	12	12	NUM
american_scientific_journal-766	51	35	weeks	week	NOUN
american_scientific_journal-766	51	36	after	after	ADP
american_scientific_journal-766	51	37	the	the	DET
american_scientific_journal-766	51	38	end	end	NOUN
american_scientific_journal-766	51	39	of	of	ADP
american_scientific_journal-766	51	40	therapy	therapy	NOUN
american_scientific_journal-766	51	41	[	[	X
american_scientific_journal-766	51	42	19	19	NUM
american_scientific_journal-766	51	43	]	]	PUNCT
american_scientific_journal-766	51	44	.	.	PUNCT
american_scientific_journal-766	52	1	also	also	ADV
american_scientific_journal-766	52	2	,	,	PUNCT
american_scientific_journal-766	52	3	the	the	DET
american_scientific_journal-766	52	4	hcv	hcv	NOUN
american_scientific_journal-766	52	5	treatment	treatment	NOUN
american_scientific_journal-766	52	6	aimed	aim	VERB
american_scientific_journal-766	52	7	to	to	PART
american_scientific_journal-766	52	8	decrease	decrease	VERB
american_scientific_journal-766	52	9	the	the	DET
american_scientific_journal-766	52	10	risk	risk	NOUN
american_scientific_journal-766	52	11	of	of	ADP
american_scientific_journal-766	52	12	virus	virus	NOUN
american_scientific_journal-766	52	13	-	-	PUNCT
american_scientific_journal-766	52	14	related	relate	VERB
american_scientific_journal-766	52	15	conditions	condition	NOUN
american_scientific_journal-766	52	16	such	such	ADJ
american_scientific_journal-766	52	17	as	as	ADP
american_scientific_journal-766	52	18	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	52	19	,	,	PUNCT
american_scientific_journal-766	52	20	hepatocellular	hepatocellular	ADJ
american_scientific_journal-766	52	21	carcinoma	carcinoma	NOUN
american_scientific_journal-766	52	22	(	(	PUNCT
american_scientific_journal-766	52	23	hcc	hcc	PROPN
american_scientific_journal-766	52	24	)	)	PUNCT
american_scientific_journal-766	52	25	,	,	PUNCT
american_scientific_journal-766	52	26	decompensated	decompensate	VERB
american_scientific_journal-766	52	27	liver	liver	NOUN
american_scientific_journal-766	52	28	disease	disease	NOUN
american_scientific_journal-766	52	29	,	,	PUNCT
american_scientific_journal-766	52	30	liver	liver	NOUN
american_scientific_journal-766	52	31	transplant	transplant	NOUN
american_scientific_journal-766	52	32	,	,	PUNCT
american_scientific_journal-766	52	33	or	or	CCONJ
american_scientific_journal-766	52	34	death	death	NOUN
american_scientific_journal-766	52	35	from	from	ADP
american_scientific_journal-766	52	36	other	other	ADJ
american_scientific_journal-766	52	37	liver	liver	NOUN
american_scientific_journal-766	52	38	-	-	PUNCT
american_scientific_journal-766	52	39	related	relate	VERB
american_scientific_journal-766	52	40	causes	cause	NOUN
american_scientific_journal-766	52	41	.	.	PUNCT
american_scientific_journal-766	53	1	svr	svr	PROPN
american_scientific_journal-766	53	2	is	be	AUX
american_scientific_journal-766	53	3	associated	associate	VERB
american_scientific_journal-766	53	4	with	with	ADP
american_scientific_journal-766	53	5	improved	improved	ADJ
american_scientific_journal-766	53	6	outcomes	outcome	NOUN
american_scientific_journal-766	53	7	in	in	ADP
american_scientific_journal-766	53	8	the	the	DET
american_scientific_journal-766	53	9	form	form	NOUN
american_scientific_journal-766	53	10	of	of	ADP
american_scientific_journal-766	53	11	reduction	reduction	NOUN
american_scientific_journal-766	53	12	in	in	ADP
american_scientific_journal-766	53	13	the	the	DET
american_scientific_journal-766	53	14	rate	rate	NOUN
american_scientific_journal-766	53	15	of	of	ADP
american_scientific_journal-766	53	16	hepatocellular	hepatocellular	ADJ
american_scientific_journal-766	53	17	carcinoma	carcinoma	NOUN
american_scientific_journal-766	53	18	(	(	PUNCT
american_scientific_journal-766	53	19	hcc	hcc	NOUN
american_scientific_journal-766	53	20	)	)	PUNCT
american_scientific_journal-766	53	21	and	and	CCONJ
american_scientific_journal-766	53	22	liver	liver	NOUN
american_scientific_journal-766	53	23	decompensation	decompensation	NOUN
american_scientific_journal-766	53	24	,	,	PUNCT
american_scientific_journal-766	53	25	and	and	CCONJ
american_scientific_journal-766	53	26	improved	improved	ADJ
american_scientific_journal-766	53	27	survival	survival	NOUN
american_scientific_journal-766	53	28	;	;	PUNCT
american_scientific_journal-766	53	29	patients	patient	NOUN
american_scientific_journal-766	53	30	who	who	PRON
american_scientific_journal-766	53	31	achieve	achieve	VERB
american_scientific_journal-766	53	32	svr	svr	PROPN
american_scientific_journal-766	53	33	are	be	AUX
american_scientific_journal-766	53	34	considered	consider	VERB
american_scientific_journal-766	53	35	to	to	PART
american_scientific_journal-766	53	36	be	be	AUX
american_scientific_journal-766	53	37	cured	cure	VERB
american_scientific_journal-766	53	38	[	[	PUNCT
american_scientific_journal-766	53	39	20	20	NUM
american_scientific_journal-766	53	40	]	]	PUNCT
american_scientific_journal-766	53	41	.	.	PUNCT
american_scientific_journal-766	54	1	2.1	2.1	NUM
american_scientific_journal-766	54	2	.	.	PUNCT
american_scientific_journal-766	55	1	early	early	ADJ
american_scientific_journal-766	55	2	antiviral	antiviral	ADJ
american_scientific_journal-766	55	3	therapy	therapy	NOUN
american_scientific_journal-766	55	4	2.1.1	2.1.1	NUM
american_scientific_journal-766	55	5	.	.	PUNCT
american_scientific_journal-766	56	1	interferon	interferon	PROPN
american_scientific_journal-766	56	2	monotherapy	monotherapy	NOUN
american_scientific_journal-766	56	3	early	early	ADJ
american_scientific_journal-766	56	4	treatment	treatment	NOUN
american_scientific_journal-766	56	5	of	of	ADP
american_scientific_journal-766	56	6	acute	acute	ADJ
american_scientific_journal-766	56	7	hepatitis	hepatitis	PROPN
american_scientific_journal-766	56	8	c	c	PROPN
american_scientific_journal-766	56	9	with	with	ADP
american_scientific_journal-766	56	10	interferon	interferon	ADJ
american_scientific_journal-766	56	11	alpha	alpha	NOUN
american_scientific_journal-766	56	12	(	(	PUNCT
american_scientific_journal-766	56	13	α	α	NOUN
american_scientific_journal-766	56	14	-	-	PUNCT
american_scientific_journal-766	56	15	ifn	ifn	NOUN
american_scientific_journal-766	56	16	)	)	PUNCT
american_scientific_journal-766	56	17	for	for	ADP
american_scientific_journal-766	56	18	24	24	NUM
american_scientific_journal-766	56	19	weeks	week	NOUN
american_scientific_journal-766	56	20	prevents	prevent	VERB
american_scientific_journal-766	56	21	chronic	chronic	ADJ
american_scientific_journal-766	56	22	infection	infection	NOUN
american_scientific_journal-766	56	23	in	in	ADP
american_scientific_journal-766	56	24	almost	almost	ADV
american_scientific_journal-766	56	25	all	all	PRON
american_scientific_journal-766	56	26	patients	patient	NOUN
american_scientific_journal-766	56	27	.	.	PUNCT
american_scientific_journal-766	57	1	type	type	NOUN
american_scientific_journal-766	57	2	i	i	PRON
american_scientific_journal-766	57	3	α	α	PROPN
american_scientific_journal-766	57	4	-	-	PUNCT
american_scientific_journal-766	57	5	ifn	ifn	PROPN
american_scientific_journal-766	57	6	was	be	AUX
american_scientific_journal-766	57	7	the	the	DET
american_scientific_journal-766	57	8	first	first	ADJ
american_scientific_journal-766	57	9	effective	effective	ADJ
american_scientific_journal-766	57	10	antiviral	antiviral	ADJ
american_scientific_journal-766	57	11	agent	agent	NOUN
american_scientific_journal-766	57	12	approved	approve	VERB
american_scientific_journal-766	57	13	for	for	ADP
american_scientific_journal-766	57	14	use	use	NOUN
american_scientific_journal-766	57	15	against	against	ADP
american_scientific_journal-766	57	16	chronic	chronic	ADJ
american_scientific_journal-766	57	17	hcv	hcv	NOUN
american_scientific_journal-766	57	18	infection	infection	NOUN
american_scientific_journal-766	57	19	in	in	ADP
american_scientific_journal-766	57	20	the	the	DET
american_scientific_journal-766	57	21	early	early	ADJ
american_scientific_journal-766	57	22	1990s	1990	NOUN
american_scientific_journal-766	57	23	,	,	PUNCT
american_scientific_journal-766	57	24	although	although	SCONJ
american_scientific_journal-766	57	25	response	response	NOUN
american_scientific_journal-766	57	26	rates	rate	NOUN
american_scientific_journal-766	57	27	were	be	AUX
american_scientific_journal-766	57	28	generally	generally	ADV
american_scientific_journal-766	57	29	<	<	X
american_scientific_journal-766	57	30	20	20	NUM
american_scientific_journal-766	57	31	%	%	NOUN
american_scientific_journal-766	57	32	[	[	X
american_scientific_journal-766	57	33	21	21	NUM
american_scientific_journal-766	57	34	]	]	PUNCT
american_scientific_journal-766	57	35	.	.	PUNCT
american_scientific_journal-766	58	1	pegylated	pegylate	VERB
american_scientific_journal-766	58	2	interferons	interferon	NOUN
american_scientific_journal-766	58	3	(	(	PUNCT
american_scientific_journal-766	58	4	pegifn	pegifn	NOUN
american_scientific_journal-766	58	5	)	)	PUNCT
american_scientific_journal-766	58	6	have	have	AUX
american_scientific_journal-766	58	7	replaced	replace	VERB
american_scientific_journal-766	58	8	conventional	conventional	ADJ
american_scientific_journal-766	58	9	interferon	interferon	NOUN
american_scientific_journal-766	58	10	in	in	ADP
american_scientific_journal-766	58	11	the	the	DET
american_scientific_journal-766	58	12	therapy	therapy	NOUN
american_scientific_journal-766	58	13	of	of	ADP
american_scientific_journal-766	58	14	chronic	chronic	ADJ
american_scientific_journal-766	58	15	hepatitis	hepatitis	PROPN
american_scientific_journal-766	58	16	c.	c.	PROPN
american_scientific_journal-766	58	17	several	several	ADJ
american_scientific_journal-766	58	18	reports	report	NOUN
american_scientific_journal-766	58	19	have	have	AUX
american_scientific_journal-766	58	20	documented	document	VERB
american_scientific_journal-766	58	21	improved	improve	VERB
american_scientific_journal-766	58	22	svr	svr	NOUN
american_scientific_journal-766	58	23	with	with	ADP
american_scientific_journal-766	58	24	peg	peg	NOUN
american_scientific_journal-766	58	25	-	-	PUNCT
american_scientific_journal-766	58	26	ifn	ifn	NOUN
american_scientific_journal-766	58	27	monotherapy	monotherapy	NOUN
american_scientific_journal-766	58	28	.	.	PUNCT
american_scientific_journal-766	59	1	in	in	ADP
american_scientific_journal-766	59	2	a	a	DET
american_scientific_journal-766	59	3	study	study	NOUN
american_scientific_journal-766	59	4	of	of	ADP
american_scientific_journal-766	59	5	patients	patient	NOUN
american_scientific_journal-766	59	6	with	with	ADP
american_scientific_journal-766	59	7	chronic	chronic	ADJ
american_scientific_journal-766	59	8	hepatitis	hepatitis	NOUN
american_scientific_journal-766	59	9	c	c	NOUN
american_scientific_journal-766	59	10	,	,	PUNCT
american_scientific_journal-766	59	11	it	it	PRON
american_scientific_journal-766	59	12	was	be	AUX
american_scientific_journal-766	59	13	found	find	VERB
american_scientific_journal-766	59	14	that	that	SCONJ
american_scientific_journal-766	59	15	peg	peg	NOUN
american_scientific_journal-766	59	16	-	-	PUNCT
american_scientific_journal-766	59	17	ifn	ifn	NOUN
american_scientific_journal-766	59	18	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	59	19	administered	administer	VERB
american_scientific_journal-766	59	20	once	once	ADV
american_scientific_journal-766	59	21	per	per	ADP
american_scientific_journal-766	59	22	week	week	NOUN
american_scientific_journal-766	59	23	was	be	AUX
american_scientific_journal-766	59	24	associated	associate	VERB
american_scientific_journal-766	59	25	with	with	ADP
american_scientific_journal-766	59	26	a	a	DET
american_scientific_journal-766	59	27	higher	high	ADJ
american_scientific_journal-766	59	28	rate	rate	NOUN
american_scientific_journal-766	59	29	of	of	ADP
american_scientific_journal-766	59	30	virologic	virologic	ADJ
american_scientific_journal-766	59	31	response	response	NOUN
american_scientific_journal-766	59	32	than	than	ADP
american_scientific_journal-766	59	33	ifn	ifn	PROPN
american_scientific_journal-766	59	34	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	59	35	at	at	ADP
american_scientific_journal-766	59	36	6	6	NUM
american_scientific_journal-766	59	37	million	million	NUM
american_scientific_journal-766	59	38	u	u	NOUN
american_scientific_journal-766	59	39	subcutaneously	subcutaneously	ADV
american_scientific_journal-766	59	40	administered	administer	VERB
american_scientific_journal-766	59	41	3	3	NUM
american_scientific_journal-766	59	42	times	time	NOUN
american_scientific_journal-766	59	43	per	per	ADP
american_scientific_journal-766	59	44	week	week	NOUN
american_scientific_journal-766	59	45	for	for	ADP
american_scientific_journal-766	59	46	12	12	NUM
american_scientific_journal-766	59	47	weeks	week	NOUN
american_scientific_journal-766	59	48	followed	follow	VERB
american_scientific_journal-766	59	49	by	by	ADP
american_scientific_journal-766	59	50	3	3	NUM
american_scientific_journal-766	59	51	million	million	NUM
american_scientific_journal-766	59	52	u	u	NOUN
american_scientific_journal-766	59	53	3	3	NUM
american_scientific_journal-766	59	54	times	time	NOUN
american_scientific_journal-766	59	55	per	per	ADP
american_scientific_journal-766	59	56	week	week	NOUN
american_scientific_journal-766	59	57	for	for	ADP
american_scientific_journal-766	59	58	36	36	NUM
american_scientific_journal-766	59	59	weeks	week	NOUN
american_scientific_journal-766	59	60	.	.	PUNCT
american_scientific_journal-766	60	1	findings	finding	NOUN
american_scientific_journal-766	60	2	were	be	AUX
american_scientific_journal-766	60	3	69	69	NUM
american_scientific_journal-766	60	4	%	%	NOUN
american_scientific_journal-766	60	5	versus	versus	ADP
american_scientific_journal-766	60	6	28	28	NUM
american_scientific_journal-766	60	7	%	%	NOUN
american_scientific_journal-766	60	8	at	at	ADP
american_scientific_journal-766	60	9	week	week	NOUN
american_scientific_journal-766	60	10	48	48	NUM
american_scientific_journal-766	60	11	of	of	ADP
american_scientific_journal-766	60	12	therapy	therapy	NOUN
american_scientific_journal-766	60	13	and	and	CCONJ
american_scientific_journal-766	60	14	39	39	NUM
american_scientific_journal-766	60	15	%	%	NOUN
american_scientific_journal-766	60	16	versus	versus	ADP
american_scientific_journal-766	60	17	19	19	NUM
american_scientific_journal-766	60	18	%	%	NOUN
american_scientific_journal-766	60	19	at	at	ADP
american_scientific_journal-766	60	20	week	week	NOUN
american_scientific_journal-766	60	21	72	72	NUM
american_scientific_journal-766	60	22	of	of	ADP
american_scientific_journal-766	60	23	therapy	therapy	NOUN
american_scientific_journal-766	60	24	[	[	X
american_scientific_journal-766	60	25	22].in	22].in	NUM
american_scientific_journal-766	60	26	a	a	DET
american_scientific_journal-766	60	27	controlled	control	VERB
american_scientific_journal-766	60	28	trial	trial	NOUN
american_scientific_journal-766	60	29	of	of	ADP
american_scientific_journal-766	60	30	persons	person	NOUN
american_scientific_journal-766	60	31	with	with	ADP
american_scientific_journal-766	60	32	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	60	33	,	,	PUNCT
american_scientific_journal-766	60	34	it	it	PRON
american_scientific_journal-766	60	35	reported	report	VERB
american_scientific_journal-766	60	36	an	an	DET
american_scientific_journal-766	60	37	svr	svr	PROPN
american_scientific_journal-766	60	38	rate	rate	NOUN
american_scientific_journal-766	60	39	of	of	ADP
american_scientific_journal-766	60	40	30	30	NUM
american_scientific_journal-766	60	41	%	%	NOUN
american_scientific_journal-766	60	42	after	after	ADP
american_scientific_journal-766	60	43	48	48	NUM
american_scientific_journal-766	60	44	weeks	week	NOUN
american_scientific_journal-766	60	45	of	of	ADP
american_scientific_journal-766	60	46	therapy	therapy	NOUN
american_scientific_journal-766	60	47	with	with	ADP
american_scientific_journal-766	60	48	peg	peg	NOUN
american_scientific_journal-766	60	49	-	-	PUNCT
american_scientific_journal-766	60	50	ifn	ifn	NOUN
american_scientific_journal-766	60	51	alfa-2a	alfa-2a	NOUN
american_scientific_journal-766	60	52	,	,	PUNCT
american_scientific_journal-766	60	53	compared	compare	VERB
american_scientific_journal-766	60	54	with	with	ADP
american_scientific_journal-766	60	55	8	8	NUM
american_scientific_journal-766	60	56	%	%	NOUN
american_scientific_journal-766	60	57	for	for	ADP
american_scientific_journal-766	60	58	patients	patient	NOUN
american_scientific_journal-766	60	59	treated	treat	VERB
american_scientific_journal-766	60	60	with	with	ADP
american_scientific_journal-766	60	61	standard	standard	ADJ
american_scientific_journal-766	60	62	ifn	ifn	PROPN
american_scientific_journal-766	60	63	alfa	alfa	NOUN
american_scientific_journal-766	60	64	.	.	PUNCT
american_scientific_journal-766	61	1	adverse	adverse	ADJ
american_scientific_journal-766	61	2	effects	effect	NOUN
american_scientific_journal-766	61	3	were	be	AUX
american_scientific_journal-766	61	4	not	not	PART
american_scientific_journal-766	61	5	significantly	significantly	ADV
american_scientific_journal-766	61	6	higher	high	ADJ
american_scientific_journal-766	61	7	with	with	ADP
american_scientific_journal-766	61	8	the	the	DET
american_scientific_journal-766	61	9	pegylated	pegylated	ADJ
american_scientific_journal-766	61	10	product	product	NOUN
american_scientific_journal-766	61	11	[	[	X
american_scientific_journal-766	61	12	23	23	NUM
american_scientific_journal-766	61	13	]	]	PUNCT
american_scientific_journal-766	61	14	.	.	PUNCT
american_scientific_journal-766	62	1	side	side	ADJ
american_scientific_journal-766	62	2	effects	effect	NOUN
american_scientific_journal-766	62	3	of	of	ADP
american_scientific_journal-766	62	4	interferon	interferon	NOUN
american_scientific_journal-766	62	5	or	or	CCONJ
american_scientific_journal-766	62	6	peg	peg	NOUN
american_scientific_journal-766	62	7	-	-	PUNCT
american_scientific_journal-766	62	8	interferon	interferon	NOUN
american_scientific_journal-766	62	9	include	include	VERB
american_scientific_journal-766	62	10	predictable	predictable	ADJ
american_scientific_journal-766	62	11	constitutional	constitutional	ADJ
american_scientific_journal-766	62	12	or	or	CCONJ
american_scientific_journal-766	62	13	“	"	PUNCT
american_scientific_journal-766	62	14	flu	flu	NOUN
american_scientific_journal-766	62	15	-	-	PUNCT
american_scientific_journal-766	62	16	like	like	ADJ
american_scientific_journal-766	62	17	”	"	PUNCT
american_scientific_journal-766	62	18	symptoms	symptom	NOUN
american_scientific_journal-766	62	19	of	of	ADP
american_scientific_journal-766	62	20	fever	fever	NOUN
american_scientific_journal-766	62	21	,	,	PUNCT
american_scientific_journal-766	62	22	chills	chill	NOUN
american_scientific_journal-766	62	23	,	,	PUNCT
american_scientific_journal-766	62	24	headache	headache	NOUN
american_scientific_journal-766	62	25	,	,	PUNCT
american_scientific_journal-766	62	26	and	and	CCONJ
american_scientific_journal-766	62	27	myalgia	myalgia	NOUN
american_scientific_journal-766	62	28	,	,	PUNCT
american_scientific_journal-766	62	29	nausea	nausea	NOUN
american_scientific_journal-766	62	30	,	,	PUNCT
american_scientific_journal-766	62	31	anorexia	anorexia	ADJ
american_scientific_journal-766	62	32	,	,	PUNCT
american_scientific_journal-766	62	33	and	and	CCONJ
american_scientific_journal-766	62	34	less	less	ADV
american_scientific_journal-766	62	35	commonly	commonly	ADV
american_scientific_journal-766	62	36	,	,	PUNCT
american_scientific_journal-766	62	37	diarrhea	diarrhea	PROPN
american_scientific_journal-766	62	38	,	,	PUNCT
american_scientific_journal-766	62	39	skin	skin	NOUN
american_scientific_journal-766	62	40	dryness	dryness	NOUN
american_scientific_journal-766	62	41	,	,	PUNCT
american_scientific_journal-766	62	42	pruritus	pruritus	NOUN
american_scientific_journal-766	62	43	,	,	PUNCT
american_scientific_journal-766	62	44	rash	rash	ADJ
american_scientific_journal-766	62	45	,	,	PUNCT
american_scientific_journal-766	62	46	hair	hair	NOUN
american_scientific_journal-766	62	47	thinning	thinning	NOUN
american_scientific_journal-766	62	48	,	,	PUNCT
american_scientific_journal-766	62	49	exacerbation	exacerbation	NOUN
american_scientific_journal-766	62	50	of	of	ADP
american_scientific_journal-766	62	51	immune	immune	NOUN
american_scientific_journal-766	62	52	-	-	PUNCT
american_scientific_journal-766	62	53	mediated	mediate	VERB
american_scientific_journal-766	62	54	disorders	disorder	NOUN
american_scientific_journal-766	62	55	,	,	PUNCT
american_scientific_journal-766	62	56	such	such	ADJ
american_scientific_journal-766	62	57	as	as	ADP
american_scientific_journal-766	62	58	thyroiditis	thyroiditis	NOUN
american_scientific_journal-766	62	59	,	,	PUNCT
american_scientific_journal-766	62	60	inflammatory	inflammatory	ADJ
american_scientific_journal-766	62	61	bowel	bowel	NOUN
american_scientific_journal-766	62	62	disease	disease	NOUN
american_scientific_journal-766	62	63	,	,	PUNCT
american_scientific_journal-766	62	64	atopic	atopic	NOUN
american_scientific_journal-766	62	65	dermatitis	dermatitis	NOUN
american_scientific_journal-766	62	66	,	,	PUNCT
american_scientific_journal-766	62	67	or	or	CCONJ
american_scientific_journal-766	62	68	psoriasis	psoriasis	NOUN
american_scientific_journal-766	62	69	.	.	PUNCT
american_scientific_journal-766	63	1	moreover	moreover	ADV
american_scientific_journal-766	63	2	,	,	PUNCT
american_scientific_journal-766	63	3	the	the	DET
american_scientific_journal-766	63	4	effect	effect	NOUN
american_scientific_journal-766	63	5	of	of	ADP
american_scientific_journal-766	63	6	ifn	ifn	PROPN
american_scientific_journal-766	63	7	on	on	ADP
american_scientific_journal-766	63	8	bone	bone	NOUN
american_scientific_journal-766	63	9	marrow	marrow	NOUN
american_scientific_journal-766	63	10	results	result	VERB
american_scientific_journal-766	63	11	in	in	ADP
american_scientific_journal-766	63	12	decreased	decrease	VERB
american_scientific_journal-766	63	13	granulocytes	granulocyte	NOUN
american_scientific_journal-766	63	14	and	and	CCONJ
american_scientific_journal-766	63	15	thrombocytes	thrombocyte	NOUN
american_scientific_journal-766	63	16	during	during	ADP
american_scientific_journal-766	63	17	treatment	treatment	NOUN
american_scientific_journal-766	63	18	[	[	X
american_scientific_journal-766	63	19	24	24	NUM
american_scientific_journal-766	63	20	]	]	PUNCT
american_scientific_journal-766	63	21	.	.	PUNCT
american_scientific_journal-766	64	1	2.1.2.peg	2.1.2.peg	NUM
american_scientific_journal-766	64	2	-	-	PUNCT
american_scientific_journal-766	64	3	ifn	ifn	NOUN
american_scientific_journal-766	64	4	therapy	therapy	NOUN
american_scientific_journal-766	64	5	with	with	ADP
american_scientific_journal-766	64	6	ribavirin	ribavirin	NOUN
american_scientific_journal-766	64	7	in	in	ADP
american_scientific_journal-766	64	8	the	the	DET
american_scientific_journal-766	64	9	last	last	ADJ
american_scientific_journal-766	64	10	decade	decade	NOUN
american_scientific_journal-766	64	11	,	,	PUNCT
american_scientific_journal-766	64	12	standard	standard	NOUN
american_scientific_journal-766	64	13	of	of	ADP
american_scientific_journal-766	64	14	care	care	NOUN
american_scientific_journal-766	64	15	anti	anti	ADJ
american_scientific_journal-766	64	16	-	-	ADJ
american_scientific_journal-766	64	17	hcv	hcv	ADJ
american_scientific_journal-766	64	18	treatment	treatment	NOUN
american_scientific_journal-766	64	19	has	have	AUX
american_scientific_journal-766	64	20	been	be	AUX
american_scientific_journal-766	64	21	founded	found	VERB
american_scientific_journal-766	64	22	on	on	ADP
american_scientific_journal-766	64	23	the	the	DET
american_scientific_journal-766	64	24	combination	combination	NOUN
american_scientific_journal-766	64	25	of	of	ADP
american_scientific_journal-766	64	26	peg	peg	NOUN
american_scientific_journal-766	64	27	-	-	PUNCT
american_scientific_journal-766	64	28	interferon	interferon	NOUN
american_scientific_journal-766	64	29	(	(	PUNCT
american_scientific_journal-766	64	30	peg	peg	NOUN
american_scientific_journal-766	64	31	-	-	PUNCT
american_scientific_journal-766	64	32	ifn	ifn	NOUN
american_scientific_journal-766	64	33	)	)	PUNCT
american_scientific_journal-766	64	34	plus	plus	CCONJ
american_scientific_journal-766	64	35	ribavirin	ribavirin	NOUN
american_scientific_journal-766	64	36	(	(	PUNCT
american_scientific_journal-766	64	37	rbv	rbv	NOUN
american_scientific_journal-766	64	38	)	)	PUNCT
american_scientific_journal-766	64	39	.	.	PUNCT
american_scientific_journal-766	65	1	in	in	ADP
american_scientific_journal-766	65	2	a	a	DET
american_scientific_journal-766	65	3	study	study	NOUN
american_scientific_journal-766	65	4	of	of	ADP
american_scientific_journal-766	65	5	ribavirin	ribavirin	NOUN
american_scientific_journal-766	65	6	in	in	ADP
american_scientific_journal-766	65	7	combination	combination	NOUN
american_scientific_journal-766	65	8	with	with	ADP
american_scientific_journal-766	65	9	either	either	PRON
american_scientific_journal-766	65	10	peg	peg	NOUN
american_scientific_journal-766	65	11	-	-	PUNCT
american_scientific_journal-766	65	12	ifn	ifn	NOUN
american_scientific_journal-766	65	13	alfa-2b	alfa-2b	NOUN
american_scientific_journal-766	65	14	or	or	CCONJ
american_scientific_journal-766	65	15	peg	peg	NOUN
american_scientific_journal-766	65	16	-	-	PUNCT
american_scientific_journal-766	65	17	ifn	ifn	NOUN
american_scientific_journal-766	65	18	3	3	NUM
american_scientific_journal-766	65	19	american	american	ADJ
american_scientific_journal-766	65	20	scientific	scientific	ADJ
american_scientific_journal-766	65	21	research	research	NOUN
american_scientific_journal-766	65	22	journal	journal	NOUN
american_scientific_journal-766	65	23	for	for	ADP
american_scientific_journal-766	65	24	engineering	engineering	NOUN
american_scientific_journal-766	65	25	,	,	PUNCT
american_scientific_journal-766	65	26	technology	technology	NOUN
american_scientific_journal-766	65	27	,	,	PUNCT
american_scientific_journal-766	65	28	and	and	CCONJ
american_scientific_journal-766	65	29	sciences	science	NOUN
american_scientific_journal-766	65	30	(	(	PUNCT
american_scientific_journal-766	65	31	asrjets	asrjet	NOUN
american_scientific_journal-766	65	32	)	)	PUNCT
american_scientific_journal-766	65	33	(	(	PUNCT
american_scientific_journal-766	65	34	2015	2015	NUM
american_scientific_journal-766	65	35	)	)	PUNCT
american_scientific_journal-766	65	36	volume	volume	NOUN
american_scientific_journal-766	65	37	13	13	NUM
american_scientific_journal-766	65	38	,	,	PUNCT
american_scientific_journal-766	65	39	no	no	DET
american_scientific_journal-766	65	40	1	1	NUM
american_scientific_journal-766	65	41	,	,	PUNCT
american_scientific_journal-766	65	42	pp	pp	ADV
american_scientific_journal-766	65	43	1	1	NUM
american_scientific_journal-766	65	44	-	-	SYM
american_scientific_journal-766	65	45	23	23	NUM
american_scientific_journal-766	65	46	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	65	47	for	for	ADP
american_scientific_journal-766	65	48	the	the	DET
american_scientific_journal-766	65	49	treatment	treatment	NOUN
american_scientific_journal-766	65	50	of	of	ADP
american_scientific_journal-766	65	51	chronic	chronic	ADJ
american_scientific_journal-766	65	52	hcv	hcv	NOUN
american_scientific_journal-766	65	53	infection	infection	NOUN
american_scientific_journal-766	65	54	,	,	PUNCT
american_scientific_journal-766	65	55	it	it	PRON
american_scientific_journal-766	65	56	reported	report	VERB
american_scientific_journal-766	65	57	a	a	DET
american_scientific_journal-766	65	58	higher	high	ADJ
american_scientific_journal-766	65	59	svr	svr	NOUN
american_scientific_journal-766	65	60	rate	rate	NOUN
american_scientific_journal-766	65	61	with	with	ADP
american_scientific_journal-766	65	62	peg	peg	NOUN
american_scientific_journal-766	65	63	-	-	PUNCT
american_scientific_journal-766	65	64	ifn	ifn	NOUN
american_scientific_journal-766	65	65	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	65	66	than	than	ADP
american_scientific_journal-766	65	67	with	with	ADP
american_scientific_journal-766	65	68	peg	peg	NOUN
american_scientific_journal-766	65	69	-	-	PUNCT
american_scientific_journal-766	65	70	ifn	ifn	PROPN
american_scientific_journal-766	65	71	alfa-2b	alfa-2b	CCONJ
american_scientific_journal-766	65	72	(	(	PUNCT
american_scientific_journal-766	65	73	68	68	NUM
american_scientific_journal-766	65	74	%	%	NOUN
american_scientific_journal-766	65	75	versus	versus	ADP
american_scientific_journal-766	65	76	54.4	54.4	NUM
american_scientific_journal-766	65	77	%	%	NOUN
american_scientific_journal-766	65	78	)	)	PUNCT
american_scientific_journal-766	66	1	[	[	X
american_scientific_journal-766	66	2	25	25	NUM
american_scientific_journal-766	66	3	]	]	PUNCT
american_scientific_journal-766	66	4	.	.	PUNCT
american_scientific_journal-766	67	1	in	in	ADP
american_scientific_journal-766	67	2	a	a	DET
american_scientific_journal-766	67	3	study	study	NOUN
american_scientific_journal-766	67	4	of	of	ADP
american_scientific_journal-766	67	5	patients	patient	NOUN
american_scientific_journal-766	67	6	coinfected	coinfecte	VERB
american_scientific_journal-766	67	7	with	with	ADP
american_scientific_journal-766	67	8	hcv	hcv	PROPN
american_scientific_journal-766	67	9	and	and	CCONJ
american_scientific_journal-766	67	10	hiv	hiv	PROPN
american_scientific_journal-766	67	11	with	with	ADP
american_scientific_journal-766	67	12	compensated	compensated	ADJ
american_scientific_journal-766	67	13	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	67	14	,	,	PUNCT
american_scientific_journal-766	67	15	it	it	PRON
american_scientific_journal-766	67	16	was	be	AUX
american_scientific_journal-766	67	17	found	find	VERB
american_scientific_journal-766	67	18	that	that	PRON
american_scientific_journal-766	67	19	svr	svr	VERB
american_scientific_journal-766	67	20	to	to	PART
american_scientific_journal-766	67	21	peg	peg	NOUN
american_scientific_journal-766	67	22	-	-	PUNCT
american_scientific_journal-766	67	23	ifn	ifn	NOUN
american_scientific_journal-766	67	24	plus	plus	CCONJ
american_scientific_journal-766	67	25	ribavirin	ribavirin	NOUN
american_scientific_journal-766	67	26	significantly	significantly	ADV
american_scientific_journal-766	67	27	reduced	reduce	VERB
american_scientific_journal-766	67	28	the	the	DET
american_scientific_journal-766	67	29	incidence	incidence	NOUN
american_scientific_journal-766	67	30	of	of	ADP
american_scientific_journal-766	67	31	liver	liver	NOUN
american_scientific_journal-766	67	32	-	-	PUNCT
american_scientific_journal-766	67	33	related	relate	VERB
american_scientific_journal-766	67	34	decompensations	decompensation	NOUN
american_scientific_journal-766	67	35	and	and	CCONJ
american_scientific_journal-766	67	36	overall	overall	ADJ
american_scientific_journal-766	67	37	mortality	mortality	NOUN
american_scientific_journal-766	68	1	[	[	X
american_scientific_journal-766	68	2	26	26	NUM
american_scientific_journal-766	68	3	]	]	PUNCT
american_scientific_journal-766	68	4	.	.	PUNCT
american_scientific_journal-766	69	1	furthermore	furthermore	ADV
american_scientific_journal-766	69	2	,	,	PUNCT
american_scientific_journal-766	69	3	[	[	X
american_scientific_journal-766	69	4	27	27	NUM
american_scientific_journal-766	69	5	]	]	PUNCT
american_scientific_journal-766	69	6	reported	report	VERB
american_scientific_journal-766	69	7	a	a	DET
american_scientific_journal-766	69	8	significantly	significantly	ADV
american_scientific_journal-766	69	9	higher	high	ADJ
american_scientific_journal-766	69	10	svr	svr	PROPN
american_scientific_journal-766	69	11	rate	rate	NOUN
american_scientific_journal-766	69	12	in	in	ADP
american_scientific_journal-766	69	13	patients	patient	NOUN
american_scientific_journal-766	69	14	given	give	VERB
american_scientific_journal-766	69	15	higher	high	ADJ
american_scientific_journal-766	69	16	-	-	PUNCT
american_scientific_journal-766	69	17	dose	dose	NOUN
american_scientific_journal-766	69	18	peg	peg	NOUN
american_scientific_journal-766	69	19	-	-	PUNCT
american_scientific_journal-766	69	20	ifn	ifn	NOUN
american_scientific_journal-766	69	21	alfa-2b	alfa-2b	CCONJ
american_scientific_journal-766	69	22	plus	plus	CCONJ
american_scientific_journal-766	69	23	ribavirin	ribavirin	NOUN
american_scientific_journal-766	69	24	than	than	ADP
american_scientific_journal-766	69	25	in	in	ADP
american_scientific_journal-766	69	26	patients	patient	NOUN
american_scientific_journal-766	69	27	given	give	VERB
american_scientific_journal-766	69	28	lower	lower	ADV
american_scientific_journal-766	69	29	-	-	PUNCT
american_scientific_journal-766	69	30	dose	dose	NOUN
american_scientific_journal-766	69	31	peg	peg	NOUN
american_scientific_journal-766	69	32	-	-	PUNCT
american_scientific_journal-766	69	33	ifn	ifn	NOUN
american_scientific_journal-766	69	34	alfa-2b	alfa-2b	CCONJ
american_scientific_journal-766	69	35	plus	plus	CCONJ
american_scientific_journal-766	69	36	ribavirin	ribavirin	NOUN
american_scientific_journal-766	69	37	or	or	CCONJ
american_scientific_journal-766	69	38	given	give	VERB
american_scientific_journal-766	69	39	ifn	ifn	PRON
american_scientific_journal-766	69	40	alfa-2b	alfa-2b	CCONJ
american_scientific_journal-766	69	41	plus	plus	CCONJ
american_scientific_journal-766	69	42	ribavirin	ribavirin	NOUN
american_scientific_journal-766	69	43	.	.	PUNCT
american_scientific_journal-766	70	1	adverse	adverse	ADJ
american_scientific_journal-766	70	2	effect	effect	NOUN
american_scientific_journal-766	70	3	profiles	profile	NOUN
american_scientific_journal-766	70	4	in	in	ADP
american_scientific_journal-766	70	5	the	the	DET
american_scientific_journal-766	70	6	3	3	NUM
american_scientific_journal-766	70	7	treatment	treatment	NOUN
american_scientific_journal-766	70	8	groups	group	NOUN
american_scientific_journal-766	70	9	were	be	AUX
american_scientific_journal-766	70	10	similar	similar	ADJ
american_scientific_journal-766	70	11	(	(	PUNCT
american_scientific_journal-766	70	12	figure	figure	NOUN
american_scientific_journal-766	70	13	1	1	NUM
american_scientific_journal-766	70	14	)	)	PUNCT
american_scientific_journal-766	70	15	figure	figure	NOUN
american_scientific_journal-766	70	16	1	1	NUM
american_scientific_journal-766	70	17	:	:	PUNCT
american_scientific_journal-766	70	18	peg	peg	NOUN
american_scientific_journal-766	70	19	-	-	PUNCT
american_scientific_journal-766	70	20	inf+rbv	inf+rbv	ADV
american_scientific_journal-766	70	21	virologic	virologic	ADJ
american_scientific_journal-766	70	22	response	response	NOUN
american_scientific_journal-766	70	23	by	by	ADP
american_scientific_journal-766	70	24	genotype	genotype	NOUN
american_scientific_journal-766	70	25	[	[	X
american_scientific_journal-766	70	26	27	27	NUM
american_scientific_journal-766	70	27	]	]	PUNCT
american_scientific_journal-766	70	28	.	.	PUNCT
american_scientific_journal-766	71	1	in	in	ADP
american_scientific_journal-766	71	2	addition	addition	NOUN
american_scientific_journal-766	71	3	,	,	PUNCT
american_scientific_journal-766	71	4	the	the	DET
american_scientific_journal-766	71	5	patients	patient	NOUN
american_scientific_journal-766	71	6	who	who	PRON
american_scientific_journal-766	71	7	received	receive	VERB
american_scientific_journal-766	71	8	peg	peg	NOUN
american_scientific_journal-766	71	9	-	-	PUNCT
american_scientific_journal-766	71	10	ifn	ifn	NOUN
american_scientific_journal-766	71	11	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	71	12	plus	plus	CCONJ
american_scientific_journal-766	71	13	ribavirin	ribavirin	NOUN
american_scientific_journal-766	71	14	had	have	VERB
american_scientific_journal-766	71	15	a	a	DET
american_scientific_journal-766	71	16	significantly	significantly	ADV
american_scientific_journal-766	71	17	higher	high	ADJ
american_scientific_journal-766	71	18	svr	svr	PROPN
american_scientific_journal-766	71	19	rate	rate	NOUN
american_scientific_journal-766	71	20	than	than	ADP
american_scientific_journal-766	71	21	patients	patient	NOUN
american_scientific_journal-766	71	22	who	who	PRON
american_scientific_journal-766	71	23	received	receive	VERB
american_scientific_journal-766	71	24	ifn	ifn	NOUN
american_scientific_journal-766	71	25	alfa-2b	alfa-2b	CCONJ
american_scientific_journal-766	71	26	plus	plus	CCONJ
american_scientific_journal-766	71	27	ribavirin	ribavirin	NOUN
american_scientific_journal-766	71	28	(	(	PUNCT
american_scientific_journal-766	71	29	56	56	NUM
american_scientific_journal-766	71	30	%	%	NOUN
american_scientific_journal-766	71	31	vs	vs	ADP
american_scientific_journal-766	71	32	44	44	NUM
american_scientific_journal-766	71	33	%	%	NOUN
american_scientific_journal-766	71	34	)	)	PUNCT
american_scientific_journal-766	71	35	or	or	CCONJ
american_scientific_journal-766	71	36	peg	peg	NOUN
american_scientific_journal-766	71	37	-	-	PUNCT
american_scientific_journal-766	71	38	ifn	ifn	NOUN
american_scientific_journal-766	71	39	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	71	40	alone	alone	ADV
american_scientific_journal-766	71	41	(	(	PUNCT
american_scientific_journal-766	71	42	56	56	NUM
american_scientific_journal-766	71	43	%	%	NOUN
american_scientific_journal-766	71	44	vs	vs	ADP
american_scientific_journal-766	71	45	29%)[28	29%)[28	NUM
american_scientific_journal-766	71	46	]	]	PUNCT
american_scientific_journal-766	71	47	.	.	PUNCT
american_scientific_journal-766	72	1	the	the	DET
american_scientific_journal-766	72	2	svr	svr	PROPN
american_scientific_journal-766	72	3	rates	rate	NOUN
american_scientific_journal-766	72	4	for	for	ADP
american_scientific_journal-766	72	5	patients	patient	NOUN
american_scientific_journal-766	72	6	with	with	ADP
american_scientific_journal-766	72	7	hcv	hcv	NOUN
american_scientific_journal-766	72	8	genotype	genotype	NOUN
american_scientific_journal-766	72	9	1	1	NUM
american_scientific_journal-766	72	10	were	be	AUX
american_scientific_journal-766	72	11	46	46	NUM
american_scientific_journal-766	72	12	%	%	NOUN
american_scientific_journal-766	72	13	,	,	PUNCT
american_scientific_journal-766	72	14	36	36	NUM
american_scientific_journal-766	72	15	%	%	NOUN
american_scientific_journal-766	72	16	,	,	PUNCT
american_scientific_journal-766	72	17	and	and	CCONJ
american_scientific_journal-766	72	18	21	21	NUM
american_scientific_journal-766	72	19	%	%	NOUN
american_scientific_journal-766	72	20	,	,	PUNCT
american_scientific_journal-766	72	21	respectively	respectively	ADV
american_scientific_journal-766	72	22	,	,	PUNCT
american_scientific_journal-766	72	23	for	for	ADP
american_scientific_journal-766	72	24	the	the	DET
american_scientific_journal-766	72	25	3	3	NUM
american_scientific_journal-766	72	26	regimens	regimen	NOUN
american_scientific_journal-766	72	27	.	.	PUNCT
american_scientific_journal-766	73	1	moreover	moreover	ADV
american_scientific_journal-766	73	2	,	,	PUNCT
american_scientific_journal-766	73	3	[	[	X
american_scientific_journal-766	73	4	29	29	NUM
american_scientific_journal-766	73	5	]	]	PUNCT
american_scientific_journal-766	73	6	reported	report	VERB
american_scientific_journal-766	73	7	that	that	SCONJ
american_scientific_journal-766	73	8	in	in	ADP
american_scientific_journal-766	73	9	patients	patient	NOUN
american_scientific_journal-766	73	10	infected	infect	VERB
american_scientific_journal-766	73	11	with	with	ADP
american_scientific_journal-766	73	12	hcv	hcv	NOUN
american_scientific_journal-766	73	13	genotype	genotype	NOUN
american_scientific_journal-766	73	14	1	1	NUM
american_scientific_journal-766	73	15	,	,	PUNCT
american_scientific_journal-766	73	16	treatment	treatment	NOUN
american_scientific_journal-766	73	17	for	for	ADP
american_scientific_journal-766	73	18	48	48	NUM
american_scientific_journal-766	73	19	weeks	week	NOUN
american_scientific_journal-766	73	20	was	be	AUX
american_scientific_journal-766	73	21	statistically	statistically	ADV
american_scientific_journal-766	73	22	superior	superior	ADJ
american_scientific_journal-766	73	23	to	to	ADP
american_scientific_journal-766	73	24	24	24	NUM
american_scientific_journal-766	73	25	weeks	week	NOUN
american_scientific_journal-766	73	26	,	,	PUNCT
american_scientific_journal-766	73	27	and	and	CCONJ
american_scientific_journal-766	73	28	standard	standard	NOUN
american_scientific_journal-766	73	29	-	-	PUNCT
american_scientific_journal-766	73	30	dose	dose	VERB
american_scientific_journal-766	73	31	ribavirin	ribavirin	NOUN
american_scientific_journal-766	73	32	was	be	AUX
american_scientific_journal-766	73	33	statistically	statistically	ADV
american_scientific_journal-766	73	34	superior	superior	ADJ
american_scientific_journal-766	73	35	to	to	ADP
american_scientific_journal-766	73	36	low	low	ADV
american_scientific_journal-766	73	37	-	-	PUNCT
american_scientific_journal-766	73	38	dose	dose	NOUN
american_scientific_journal-766	73	39	ribavirin	ribavirin	NOUN
american_scientific_journal-766	73	40	.	.	PUNCT
american_scientific_journal-766	74	1	a	a	DET
american_scientific_journal-766	74	2	major	major	ADJ
american_scientific_journal-766	74	3	barrier	barrier	NOUN
american_scientific_journal-766	74	4	to	to	ADP
american_scientific_journal-766	74	5	successful	successful	ADJ
american_scientific_journal-766	74	6	treatment	treatment	NOUN
american_scientific_journal-766	74	7	is	be	AUX
american_scientific_journal-766	74	8	the	the	DET
american_scientific_journal-766	74	9	association	association	NOUN
american_scientific_journal-766	74	10	of	of	ADP
american_scientific_journal-766	74	11	peginterferon	peginterferon	NOUN
american_scientific_journal-766	74	12	/	/	SYM
american_scientific_journal-766	74	13	ribavirin	ribavirin	NOUN
american_scientific_journal-766	74	14	therapy	therapy	NOUN
american_scientific_journal-766	74	15	with	with	ADP
american_scientific_journal-766	74	16	frequent	frequent	ADJ
american_scientific_journal-766	74	17	and	and	CCONJ
american_scientific_journal-766	74	18	sometimes	sometimes	ADV
american_scientific_journal-766	74	19	serious	serious	ADJ
american_scientific_journal-766	74	20	adverse	adverse	ADJ
american_scientific_journal-766	74	21	effects	effect	NOUN
american_scientific_journal-766	74	22	.	.	PUNCT
american_scientific_journal-766	75	1	in	in	ADP
american_scientific_journal-766	75	2	clinical	clinical	ADJ
american_scientific_journal-766	75	3	trials	trial	NOUN
american_scientific_journal-766	75	4	,	,	PUNCT
american_scientific_journal-766	75	5	approximately	approximately	ADV
american_scientific_journal-766	75	6	10	10	NUM
american_scientific_journal-766	75	7	-	-	SYM
american_scientific_journal-766	75	8	15	15	NUM
american_scientific_journal-766	75	9	%	%	NOUN
american_scientific_journal-766	75	10	of	of	ADP
american_scientific_journal-766	75	11	treated	treat	VERB
american_scientific_journal-766	75	12	patients	patient	NOUN
american_scientific_journal-766	75	13	discontinue	discontinue	VERB
american_scientific_journal-766	75	14	peginterferon	peginterferon	NOUN
american_scientific_journal-766	75	15	and	and	CCONJ
american_scientific_journal-766	75	16	ribavirin	ribavirin	NOUN
american_scientific_journal-766	75	17	due	due	ADP
american_scientific_journal-766	75	18	to	to	ADP
american_scientific_journal-766	75	19	adverse	adverse	ADJ
american_scientific_journal-766	75	20	events	event	NOUN
american_scientific_journal-766	75	21	;	;	PUNCT
american_scientific_journal-766	75	22	however	however	ADV
american_scientific_journal-766	75	23	,	,	PUNCT
american_scientific_journal-766	75	24	in	in	ADP
american_scientific_journal-766	75	25	routine	routine	ADJ
american_scientific_journal-766	75	26	clinical	clinical	ADJ
american_scientific_journal-766	75	27	practice	practice	NOUN
american_scientific_journal-766	75	28	,	,	PUNCT
american_scientific_journal-766	75	29	the	the	DET
american_scientific_journal-766	75	30	rate	rate	NOUN
american_scientific_journal-766	75	31	of	of	ADP
american_scientific_journal-766	75	32	treatment	treatment	NOUN
american_scientific_journal-766	75	33	discontinuation	discontinuation	NOUN
american_scientific_journal-766	75	34	has	have	AUX
american_scientific_journal-766	75	35	been	be	AUX
american_scientific_journal-766	75	36	reported	report	VERB
american_scientific_journal-766	75	37	to	to	PART
american_scientific_journal-766	75	38	be	be	AUX
american_scientific_journal-766	75	39	substantially	substantially	ADV
american_scientific_journal-766	75	40	higher	high	ADJ
american_scientific_journal-766	75	41	,	,	PUNCT
american_scientific_journal-766	75	42	and	and	CCONJ
american_scientific_journal-766	75	43	the	the	DET
american_scientific_journal-766	75	44	side	side	NOUN
american_scientific_journal-766	75	45	effects	effect	NOUN
american_scientific_journal-766	75	46	of	of	ADP
american_scientific_journal-766	75	47	peginterferon	peginterferon	NOUN
american_scientific_journal-766	75	48	/	/	SYM
american_scientific_journal-766	75	49	ribavirin	ribavirin	NOUN
american_scientific_journal-766	75	50	therapy	therapy	NOUN
american_scientific_journal-766	75	51	affect	affect	VERB
american_scientific_journal-766	75	52	virtually	virtually	ADV
american_scientific_journal-766	75	53	all	all	DET
american_scientific_journal-766	75	54	organ	organ	NOUN
american_scientific_journal-766	75	55	systems	system	NOUN
american_scientific_journal-766	75	56	[	[	X
american_scientific_journal-766	75	57	30	30	NUM
american_scientific_journal-766	75	58	]	]	PUNCT
american_scientific_journal-766	75	59	.	.	PUNCT
american_scientific_journal-766	76	1	2.2	2.2	NUM
american_scientific_journal-766	76	2	.	.	PUNCT
american_scientific_journal-766	77	1	a	a	DET
american_scientific_journal-766	77	2	new	new	ADJ
american_scientific_journal-766	77	3	era	era	NOUN
american_scientific_journal-766	77	4	of	of	ADP
american_scientific_journal-766	77	5	hcv	hcv	PROPN
american_scientific_journal-766	77	6	management	management	NOUN
american_scientific_journal-766	77	7	's	be	AUX
american_scientific_journal-766	77	8	in	in	ADP
american_scientific_journal-766	77	9	the	the	DET
american_scientific_journal-766	77	10	last	last	ADJ
american_scientific_journal-766	77	11	decade	decade	NOUN
american_scientific_journal-766	77	12	,	,	PUNCT
american_scientific_journal-766	77	13	standard	standard	NOUN
american_scientific_journal-766	77	14	of	of	ADP
american_scientific_journal-766	77	15	care	care	NOUN
american_scientific_journal-766	77	16	anti	anti	ADJ
american_scientific_journal-766	77	17	-	-	ADJ
american_scientific_journal-766	77	18	hcv	hcv	ADJ
american_scientific_journal-766	77	19	treatment	treatment	NOUN
american_scientific_journal-766	77	20	has	have	AUX
american_scientific_journal-766	77	21	been	be	AUX
american_scientific_journal-766	77	22	founded	found	VERB
american_scientific_journal-766	77	23	on	on	ADP
american_scientific_journal-766	77	24	the	the	DET
american_scientific_journal-766	77	25	combination	combination	NOUN
american_scientific_journal-766	77	26	of	of	ADP
american_scientific_journal-766	77	27	peginterferon	peginterferon	NOUN
american_scientific_journal-766	77	28	(	(	PUNCT
american_scientific_journal-766	77	29	peg	peg	NOUN
american_scientific_journal-766	77	30	-	-	PUNCT
american_scientific_journal-766	77	31	ifn	ifn	NOUN
american_scientific_journal-766	77	32	)	)	PUNCT
american_scientific_journal-766	77	33	plus	plus	CCONJ
american_scientific_journal-766	77	34	ribavirin	ribavirin	NOUN
american_scientific_journal-766	77	35	(	(	PUNCT
american_scientific_journal-766	77	36	rbv	rbv	NOUN
american_scientific_journal-766	77	37	)	)	PUNCT
american_scientific_journal-766	77	38	,	,	PUNCT
american_scientific_journal-766	77	39	whose	whose	DET
american_scientific_journal-766	77	40	main	main	ADJ
american_scientific_journal-766	77	41	disadvantages	disadvantage	NOUN
american_scientific_journal-766	77	42	were	be	AUX
american_scientific_journal-766	77	43	suboptimal	suboptimal	ADJ
american_scientific_journal-766	77	44	rates	rate	NOUN
american_scientific_journal-766	77	45	of	of	ADP
american_scientific_journal-766	77	46	sustained	sustain	VERB
american_scientific_journal-766	77	47	virological	virological	ADJ
american_scientific_journal-766	77	48	response	response	NOUN
american_scientific_journal-766	77	49	(	(	PUNCT
american_scientific_journal-766	77	50	svr	svr	PROPN
american_scientific_journal-766	77	51	)	)	PUNCT
american_scientific_journal-766	77	52	in	in	ADP
american_scientific_journal-766	77	53	difficult	difficult	ADJ
american_scientific_journal-766	77	54	-	-	PUNCT
american_scientific_journal-766	77	55	to	to	ADP
american_scientific_journal-766	77	56	-	-	PUNCT
american_scientific_journal-766	77	57	treat	treat	VERB
american_scientific_journal-766	77	58	patients	patient	NOUN
american_scientific_journal-766	77	59	(	(	PUNCT
american_scientific_journal-766	77	60	hcv	hcv	PROPN
american_scientific_journal-766	77	61	genotype	genotype	NOUN
american_scientific_journal-766	77	62	1–4	1–4	PROPN
american_scientific_journal-766	77	63	,	,	PUNCT
american_scientific_journal-766	77	64	advanced	advanced	ADJ
american_scientific_journal-766	77	65	liver	liver	NOUN
american_scientific_journal-766	77	66	fibrosis	fibrosis	NOUN
american_scientific_journal-766	77	67	)	)	PUNCT
american_scientific_journal-766	77	68	and	and	CCONJ
american_scientific_journal-766	77	69	,	,	PUNCT
american_scientific_journal-766	77	70	most	most	ADJ
american_scientific_journal-766	77	71	of	of	ADP
american_scientific_journal-766	77	72	all	all	PRON
american_scientific_journal-766	77	73	,	,	PUNCT
american_scientific_journal-766	77	74	side	side	ADJ
american_scientific_journal-766	77	75	effects	effect	NOUN
american_scientific_journal-766	77	76	profile	profile	VERB
american_scientific_journal-766	77	77	resulting	result	VERB
american_scientific_journal-766	77	78	in	in	ADP
american_scientific_journal-766	77	79	poor	poor	ADJ
american_scientific_journal-766	77	80	tolerability	tolerability	NOUN
american_scientific_journal-766	77	81	and	and	CCONJ
american_scientific_journal-766	77	82	treatment	treatment	NOUN
american_scientific_journal-766	77	83	contraindication	contraindication	NOUN
american_scientific_journal-766	77	84	in	in	ADP
american_scientific_journal-766	77	85	some	some	DET
american_scientific_journal-766	77	86	patient	patient	ADJ
american_scientific_journal-766	77	87	subsets	subset	NOUN
american_scientific_journal-766	77	88	(	(	PUNCT
american_scientific_journal-766	77	89	decompensated	decompensate	VERB
american_scientific_journal-766	77	90	liver	liver	NOUN
american_scientific_journal-766	77	91	disease	disease	NOUN
american_scientific_journal-766	77	92	and	and	CCONJ
american_scientific_journal-766	77	93	autoimmune	autoimmune	ADJ
american_scientific_journal-766	77	94	disorders)[31].therefore	disorders)[31].therefore	NOUN
american_scientific_journal-766	77	95	,	,	PUNCT
american_scientific_journal-766	77	96	strategies	strategy	NOUN
american_scientific_journal-766	77	97	to	to	PART
american_scientific_journal-766	77	98	improve	improve	VERB
american_scientific_journal-766	77	99	svr	svr	PROPN
american_scientific_journal-766	77	100	rates	rate	NOUN
american_scientific_journal-766	77	101	have	have	VERB
american_scientific_journal-766	77	102	4	4	NUM
american_scientific_journal-766	77	103	american	american	ADJ
american_scientific_journal-766	77	104	scientific	scientific	ADJ
american_scientific_journal-766	77	105	research	research	NOUN
american_scientific_journal-766	77	106	journal	journal	NOUN
american_scientific_journal-766	77	107	for	for	ADP
american_scientific_journal-766	77	108	engineering	engineering	NOUN
american_scientific_journal-766	77	109	,	,	PUNCT
american_scientific_journal-766	77	110	technology	technology	NOUN
american_scientific_journal-766	77	111	,	,	PUNCT
american_scientific_journal-766	77	112	and	and	CCONJ
american_scientific_journal-766	77	113	sciences	science	NOUN
american_scientific_journal-766	77	114	(	(	PUNCT
american_scientific_journal-766	77	115	asrjets	asrjet	NOUN
american_scientific_journal-766	77	116	)	)	PUNCT
american_scientific_journal-766	77	117	(	(	PUNCT
american_scientific_journal-766	77	118	2015	2015	NUM
american_scientific_journal-766	77	119	)	)	PUNCT
american_scientific_journal-766	77	120	volume	volume	NOUN
american_scientific_journal-766	77	121	13	13	NUM
american_scientific_journal-766	77	122	,	,	PUNCT
american_scientific_journal-766	77	123	no	no	DET
american_scientific_journal-766	77	124	1	1	NUM
american_scientific_journal-766	77	125	,	,	PUNCT
american_scientific_journal-766	77	126	pp	pp	ADV
american_scientific_journal-766	77	127	1	1	NUM
american_scientific_journal-766	77	128	-	-	SYM
american_scientific_journal-766	77	129	23	23	NUM
american_scientific_journal-766	77	130	been	be	VERB
american_scientific_journal-766	77	131	an	an	DET
american_scientific_journal-766	77	132	important	important	ADJ
american_scientific_journal-766	77	133	issue	issue	NOUN
american_scientific_journal-766	77	134	for	for	ADP
american_scientific_journal-766	77	135	clinical	clinical	ADJ
american_scientific_journal-766	77	136	physicians	physician	NOUN
american_scientific_journal-766	77	137	.	.	PUNCT
american_scientific_journal-766	78	1	during	during	ADP
american_scientific_journal-766	78	2	the	the	DET
american_scientific_journal-766	78	3	last	last	ADJ
american_scientific_journal-766	78	4	years	year	NOUN
american_scientific_journal-766	78	5	,	,	PUNCT
american_scientific_journal-766	78	6	intensive	intensive	ADJ
american_scientific_journal-766	78	7	efforts	effort	NOUN
american_scientific_journal-766	78	8	focused	focus	VERB
american_scientific_journal-766	78	9	on	on	ADP
american_scientific_journal-766	78	10	the	the	DET
american_scientific_journal-766	78	11	development	development	NOUN
american_scientific_journal-766	78	12	of	of	ADP
american_scientific_journal-766	78	13	direct	direct	ADJ
american_scientific_journal-766	78	14	acting	act	VERB
american_scientific_journal-766	78	15	antiviral	antiviral	ADJ
american_scientific_journal-766	78	16	agents	agent	NOUN
american_scientific_journal-766	78	17	(	(	PUNCT
american_scientific_journal-766	78	18	daas	daas	NOUN
american_scientific_journal-766	78	19	)	)	PUNCT
american_scientific_journal-766	78	20	that	that	PRON
american_scientific_journal-766	78	21	can	can	AUX
american_scientific_journal-766	78	22	block	block	VERB
american_scientific_journal-766	78	23	the	the	DET
american_scientific_journal-766	78	24	activity	activity	NOUN
american_scientific_journal-766	78	25	of	of	ADP
american_scientific_journal-766	78	26	viral	viral	ADJ
american_scientific_journal-766	78	27	enzymes	enzyme	NOUN
american_scientific_journal-766	78	28	targeting	target	VERB
american_scientific_journal-766	78	29	either	either	CCONJ
american_scientific_journal-766	78	30	ns3	ns3	NOUN
american_scientific_journal-766	78	31	-	-	PUNCT
american_scientific_journal-766	78	32	4a	4a	NOUN
american_scientific_journal-766	78	33	serine	serine	NOUN
american_scientific_journal-766	78	34	protease	protease	NOUN
american_scientific_journal-766	78	35	,	,	PUNCT
american_scientific_journal-766	78	36	which	which	PRON
american_scientific_journal-766	78	37	block	block	VERB
american_scientific_journal-766	78	38	hcv	hcv	X
american_scientific_journal-766	78	39	polyprotein	polyprotein	ADJ
american_scientific_journal-766	78	40	processing	processing	NOUN
american_scientific_journal-766	78	41	,	,	PUNCT
american_scientific_journal-766	78	42	or	or	CCONJ
american_scientific_journal-766	78	43	hcv	hcv	NOUN
american_scientific_journal-766	78	44	replication	replication	NOUN
american_scientific_journal-766	78	45	[	[	X
american_scientific_journal-766	78	46	32	32	NUM
american_scientific_journal-766	78	47	]	]	PUNCT
american_scientific_journal-766	78	48	.	.	PUNCT
american_scientific_journal-766	79	1	daas	daas	NOUN
american_scientific_journal-766	79	2	of	of	ADP
american_scientific_journal-766	79	3	all	all	DET
american_scientific_journal-766	79	4	the	the	DET
american_scientific_journal-766	79	5	major	major	ADJ
american_scientific_journal-766	79	6	classes	class	NOUN
american_scientific_journal-766	79	7	were	be	AUX
american_scientific_journal-766	79	8	designed	design	VERB
american_scientific_journal-766	79	9	to	to	PART
american_scientific_journal-766	79	10	directly	directly	ADV
american_scientific_journal-766	79	11	inhibit	inhibit	VERB
american_scientific_journal-766	79	12	viral	viral	ADJ
american_scientific_journal-766	79	13	enzymes	enzyme	NOUN
american_scientific_journal-766	79	14	and	and	CCONJ
american_scientific_journal-766	79	15	proteins	protein	NOUN
american_scientific_journal-766	79	16	.	.	PUNCT
american_scientific_journal-766	80	1	the	the	DET
american_scientific_journal-766	80	2	ns	ns	ADJ
american_scientific_journal-766	80	3	proteins	protein	NOUN
american_scientific_journal-766	80	4	ns3/4a	ns3/4a	PRON
american_scientific_journal-766	80	5	protease	protease	NOUN
american_scientific_journal-766	80	6	–	–	PUNCT
american_scientific_journal-766	80	7	helicase	helicase	NOUN
american_scientific_journal-766	80	8	and	and	CCONJ
american_scientific_journal-766	80	9	ns5b	ns5b	PROPN
american_scientific_journal-766	80	10	rdrp	rdrp	NOUN
american_scientific_journal-766	80	11	and	and	CCONJ
american_scientific_journal-766	80	12	the	the	DET
american_scientific_journal-766	80	13	ns5a	ns5a	ADJ
american_scientific_journal-766	80	14	protein	protein	NOUN
american_scientific_journal-766	80	15	all	all	PRON
american_scientific_journal-766	80	16	perform	perform	VERB
american_scientific_journal-766	80	17	crucial	crucial	ADJ
american_scientific_journal-766	80	18	activities	activity	NOUN
american_scientific_journal-766	80	19	for	for	ADP
american_scientific_journal-766	80	20	the	the	DET
american_scientific_journal-766	80	21	viral	viral	ADJ
american_scientific_journal-766	80	22	life	life	NOUN
american_scientific_journal-766	80	23	cycle	cycle	NOUN
american_scientific_journal-766	80	24	and	and	CCONJ
american_scientific_journal-766	80	25	potentially	potentially	ADV
american_scientific_journal-766	80	26	,	,	PUNCT
american_scientific_journal-766	80	27	each	each	DET
american_scientific_journal-766	80	28	step	step	NOUN
american_scientific_journal-766	80	29	of	of	ADP
american_scientific_journal-766	80	30	the	the	DET
american_scientific_journal-766	80	31	viral	viral	ADJ
american_scientific_journal-766	80	32	cycle	cycle	NOUN
american_scientific_journal-766	80	33	is	be	AUX
american_scientific_journal-766	80	34	a	a	DET
american_scientific_journal-766	80	35	target	target	NOUN
american_scientific_journal-766	80	36	for	for	ADP
american_scientific_journal-766	80	37	drug	drug	NOUN
american_scientific_journal-766	80	38	development	development	NOUN
american_scientific_journal-766	80	39	.	.	PUNCT
american_scientific_journal-766	81	1	the	the	DET
american_scientific_journal-766	81	2	new	new	ADJ
american_scientific_journal-766	81	3	group	group	NOUN
american_scientific_journal-766	81	4	of	of	ADP
american_scientific_journal-766	81	5	protease	protease	NOUN
american_scientific_journal-766	81	6	inhibitors	inhibitor	NOUN
american_scientific_journal-766	81	7	has	have	AUX
american_scientific_journal-766	81	8	improved	improve	VERB
american_scientific_journal-766	81	9	svr	svr	PROPN
american_scientific_journal-766	81	10	to	to	ADP
american_scientific_journal-766	81	11	a	a	DET
american_scientific_journal-766	81	12	great	great	ADJ
american_scientific_journal-766	81	13	extent	extent	NOUN
american_scientific_journal-766	81	14	and	and	CCONJ
american_scientific_journal-766	81	15	various	various	ADJ
american_scientific_journal-766	81	16	other	other	ADJ
american_scientific_journal-766	81	17	groups	group	NOUN
american_scientific_journal-766	81	18	of	of	ADP
american_scientific_journal-766	81	19	drugs	drug	NOUN
american_scientific_journal-766	81	20	nucleotide	nucleotide	NOUN
american_scientific_journal-766	81	21	and	and	CCONJ
american_scientific_journal-766	81	22	non	non	ADJ
american_scientific_journal-766	81	23	-	-	ADJ
american_scientific_journal-766	81	24	nucleoside	nucleoside	ADJ
american_scientific_journal-766	81	25	ns5b	ns5b	ADJ
american_scientific_journal-766	81	26	inhibitors	inhibitor	NOUN
american_scientific_journal-766	81	27	,	,	PUNCT
american_scientific_journal-766	81	28	ns5a	ns5a	ADJ
american_scientific_journal-766	81	29	inhibitors	inhibitor	NOUN
american_scientific_journal-766	81	30	and	and	CCONJ
american_scientific_journal-766	81	31	others	other	NOUN
american_scientific_journal-766	81	32	have	have	AUX
american_scientific_journal-766	81	33	certainly	certainly	ADV
american_scientific_journal-766	81	34	opened	open	VERB
american_scientific_journal-766	81	35	the	the	DET
american_scientific_journal-766	81	36	flood	flood	NOUN
american_scientific_journal-766	81	37	gates	gate	NOUN
american_scientific_journal-766	81	38	,	,	PUNCT
american_scientific_journal-766	81	39	with	with	ADP
american_scientific_journal-766	81	40	various	various	ADJ
american_scientific_journal-766	81	41	drugs	drug	NOUN
american_scientific_journal-766	81	42	standing	stand	VERB
american_scientific_journal-766	81	43	in	in	ADP
american_scientific_journal-766	81	44	line	line	NOUN
american_scientific_journal-766	81	45	for	for	ADP
american_scientific_journal-766	81	46	approval	approval	NOUN
american_scientific_journal-766	82	1	[	[	X
american_scientific_journal-766	82	2	33	33	NUM
american_scientific_journal-766	82	3	]	]	PUNCT
american_scientific_journal-766	82	4	.	.	PUNCT
american_scientific_journal-766	83	1	moreover	moreover	ADV
american_scientific_journal-766	83	2	,	,	PUNCT
american_scientific_journal-766	83	3	direct	direct	ADJ
american_scientific_journal-766	83	4	acting	act	VERB
american_scientific_journal-766	83	5	antivirals	antiviral	NOUN
american_scientific_journal-766	83	6	(	(	PUNCT
american_scientific_journal-766	83	7	daas	daas	NOUN
american_scientific_journal-766	83	8	)	)	PUNCT
american_scientific_journal-766	83	9	promised	promise	VERB
american_scientific_journal-766	83	10	to	to	PART
american_scientific_journal-766	83	11	open	open	VERB
american_scientific_journal-766	83	12	a	a	DET
american_scientific_journal-766	83	13	new	new	ADJ
american_scientific_journal-766	83	14	era	era	NOUN
american_scientific_journal-766	83	15	in	in	ADP
american_scientific_journal-766	83	16	treating	treat	VERB
american_scientific_journal-766	83	17	chronic	chronic	ADJ
american_scientific_journal-766	83	18	hcv	hcv	NOUN
american_scientific_journal-766	83	19	infection	infection	NOUN
american_scientific_journal-766	83	20	by	by	ADP
american_scientific_journal-766	83	21	increasing	increase	VERB
american_scientific_journal-766	83	22	svr	svr	PROPN
american_scientific_journal-766	83	23	rates	rate	NOUN
american_scientific_journal-766	83	24	,	,	PUNCT
american_scientific_journal-766	83	25	providing	provide	VERB
american_scientific_journal-766	83	26	shortened	shorten	VERB
american_scientific_journal-766	83	27	and	and	CCONJ
american_scientific_journal-766	83	28	simplified	simplified	ADJ
american_scientific_journal-766	83	29	regimens	regimen	NOUN
american_scientific_journal-766	83	30	while	while	SCONJ
american_scientific_journal-766	83	31	also	also	ADV
american_scientific_journal-766	83	32	minimizing	minimize	VERB
american_scientific_journal-766	83	33	treatment	treatment	NOUN
american_scientific_journal-766	83	34	-	-	PUNCT
american_scientific_journal-766	83	35	related	relate	VERB
american_scientific_journal-766	83	36	side	side	NOUN
american_scientific_journal-766	83	37	effects	effect	NOUN
american_scientific_journal-766	83	38	.	.	PUNCT
american_scientific_journal-766	84	1	three	three	NUM
american_scientific_journal-766	84	2	major	major	ADJ
american_scientific_journal-766	84	3	classes	class	NOUN
american_scientific_journal-766	84	4	of	of	ADP
american_scientific_journal-766	84	5	daa	daa	PROPN
american_scientific_journal-766	84	6	dominated	dominate	VERB
american_scientific_journal-766	84	7	the	the	DET
american_scientific_journal-766	84	8	scenario	scenario	NOUN
american_scientific_journal-766	84	9	at	at	ADP
american_scientific_journal-766	84	10	different	different	ADJ
american_scientific_journal-766	84	11	stages	stage	NOUN
american_scientific_journal-766	84	12	of	of	ADP
american_scientific_journal-766	84	13	development	development	NOUN
american_scientific_journal-766	84	14	and	and	CCONJ
american_scientific_journal-766	84	15	clinical	clinical	ADJ
american_scientific_journal-766	84	16	practice	practice	NOUN
american_scientific_journal-766	84	17	:	:	PUNCT
american_scientific_journal-766	84	18	1	1	NUM
american_scientific_journal-766	84	19	-	-	PUNCT
american_scientific_journal-766	84	20	ns3/4a	ns3/4a	NUM
american_scientific_journal-766	84	21	protease	protease	NOUN
american_scientific_journal-766	84	22	inhibitors	inhibitor	NOUN
american_scientific_journal-766	84	23	,	,	PUNCT
american_scientific_journal-766	84	24	2	2	NUM
american_scientific_journal-766	84	25	-	-	PUNCT
american_scientific_journal-766	84	26	ns5a	ns5a	NOUN
american_scientific_journal-766	84	27	inhibitors	inhibitor	NOUN
american_scientific_journal-766	84	28	and	and	CCONJ
american_scientific_journal-766	84	29	3	3	NUM
american_scientific_journal-766	84	30	-	-	ADJ
american_scientific_journal-766	84	31	ns5b	ns5b	ADJ
american_scientific_journal-766	84	32	polymerase	polymerase	NOUN
american_scientific_journal-766	84	33	inhibitors	inhibitor	NOUN
american_scientific_journal-766	84	34	,	,	PUNCT
american_scientific_journal-766	84	35	which	which	PRON
american_scientific_journal-766	84	36	can	can	AUX
american_scientific_journal-766	84	37	be	be	AUX
american_scientific_journal-766	84	38	subdivided	subdivide	VERB
american_scientific_journal-766	84	39	into	into	ADP
american_scientific_journal-766	84	40	nucleoside	nucleoside	ADJ
american_scientific_journal-766	84	41	inhibitors	inhibitor	NOUN
american_scientific_journal-766	84	42	(	(	PUNCT
american_scientific_journal-766	84	43	nis	nis	NOUN
american_scientific_journal-766	84	44	)	)	PUNCT
american_scientific_journal-766	84	45	or	or	CCONJ
american_scientific_journal-766	84	46	nonnucleoside	nonnucleoside	ADJ
american_scientific_journal-766	84	47	inhibitors	inhibitor	NOUN
american_scientific_journal-766	84	48	(	(	PUNCT
american_scientific_journal-766	84	49	nnis	nnis	PROPN
american_scientific_journal-766	84	50	)	)	PUNCT
american_scientific_journal-766	85	1	[	[	X
american_scientific_journal-766	85	2	34	34	NUM
american_scientific_journal-766	85	3	]	]	PUNCT
american_scientific_journal-766	85	4	(	(	PUNCT
american_scientific_journal-766	85	5	table	table	NOUN
american_scientific_journal-766	85	6	1	1	NUM
american_scientific_journal-766	85	7	)	)	PUNCT
american_scientific_journal-766	85	8	.	.	PUNCT
american_scientific_journal-766	86	1	table	table	NOUN
american_scientific_journal-766	86	2	1	1	NUM
american_scientific_journal-766	86	3	:	:	PUNCT
american_scientific_journal-766	86	4	comparisons	comparison	NOUN
american_scientific_journal-766	86	5	between	between	ADP
american_scientific_journal-766	86	6	the	the	DET
american_scientific_journal-766	86	7	major	major	ADJ
american_scientific_journal-766	86	8	direct	direct	ADJ
american_scientific_journal-766	86	9	-	-	PUNCT
american_scientific_journal-766	86	10	acting	act	VERB
american_scientific_journal-766	86	11	antiviral	antiviral	ADJ
american_scientific_journal-766	86	12	drugs	drug	NOUN
american_scientific_journal-766	86	13	in	in	ADP
american_scientific_journal-766	86	14	safety	safety	NOUN
american_scientific_journal-766	86	15	and	and	CCONJ
american_scientific_journal-766	86	16	efficacy	efficacy	NOUN
american_scientific_journal-766	86	17	[	[	X
american_scientific_journal-766	86	18	34	34	NUM
american_scientific_journal-766	86	19	]	]	X
american_scientific_journal-766	86	20	characteristic	characteristic	ADJ
american_scientific_journal-766	86	21	ns3/4a	ns3/4a	PROPN
american_scientific_journal-766	86	22	nis	nis	X
american_scientific_journal-766	86	23	nnis	nnis	PROPN
american_scientific_journal-766	86	24	ns5a	ns5a	PROPN
american_scientific_journal-766	86	25	inhibitors	inhibitor	NOUN
american_scientific_journal-766	86	26	potency	potency	NOUN
american_scientific_journal-766	86	27	high	high	ADJ
american_scientific_journal-766	86	28	for	for	ADP
american_scientific_journal-766	86	29	gt1	gt1	PROPN
american_scientific_journal-766	86	30	variable	variable	NOUN
american_scientific_journal-766	86	31	for	for	ADP
american_scientific_journal-766	86	32	gt2–4	gt2–4	PROPN
american_scientific_journal-766	86	33	moderate	moderate	ADJ
american_scientific_journal-766	86	34	to	to	ADP
american_scientific_journal-766	86	35	high	high	ADJ
american_scientific_journal-766	86	36	variable	variable	NOUN
american_scientific_journal-766	86	37	among	among	ADP
american_scientific_journal-766	86	38	gts	gts	PROPN
american_scientific_journal-766	86	39	high	high	ADJ
american_scientific_journal-766	86	40	;	;	PUNCT
american_scientific_journal-766	86	41	multiple	multiple	ADJ
american_scientific_journal-766	86	42	among	among	ADP
american_scientific_journal-766	86	43	gt	gt	PROPN
american_scientific_journal-766	86	44	barrier	barrier	NOUN
american_scientific_journal-766	86	45	to	to	ADP
american_scientific_journal-766	86	46	resistance	resistance	NOUN
american_scientific_journal-766	86	47	low	low	ADJ
american_scientific_journal-766	86	48	;	;	PUNCT
american_scientific_journal-766	86	49	gt1a<1b	gt1a<1b	PROPN
american_scientific_journal-766	86	50	very	very	ADV
american_scientific_journal-766	86	51	high	high	ADJ
american_scientific_journal-766	86	52	;	;	PUNCT
american_scientific_journal-766	86	53	gt1a=1b	gt1a=1b	ADP
american_scientific_journal-766	86	54	very	very	ADV
american_scientific_journal-766	86	55	low	low	ADJ
american_scientific_journal-766	86	56	;	;	PUNCT
american_scientific_journal-766	86	57	gt1a<1b	gt1a<1b	NOUN
american_scientific_journal-766	86	58	low	low	ADJ
american_scientific_journal-766	86	59	;	;	PUNCT
american_scientific_journal-766	86	60	gt1a<1b	gt1a<1b	NOUN
american_scientific_journal-766	86	61	drug	drug	NOUN
american_scientific_journal-766	86	62	interaction	interaction	NOUN
american_scientific_journal-766	86	63	high	high	ADJ
american_scientific_journal-766	86	64	low	low	ADJ
american_scientific_journal-766	86	65	variable	variable	NOUN
american_scientific_journal-766	86	66	low	low	ADJ
american_scientific_journal-766	86	67	to	to	ADP
american_scientific_journal-766	86	68	moderate	moderate	ADJ
american_scientific_journal-766	86	69	toxicity	toxicity	NOUN
american_scientific_journal-766	86	70	high	high	ADJ
american_scientific_journal-766	86	71	for	for	ADP
american_scientific_journal-766	86	72	first	first	ADJ
american_scientific_journal-766	86	73	generation	generation	NOUN
american_scientific_journal-766	86	74	rash	rash	NOUN
american_scientific_journal-766	86	75	,	,	PUNCT
american_scientific_journal-766	86	76	anemia	anemia	NOUN
american_scientific_journal-766	86	77	,	,	PUNCT
american_scientific_journal-766	86	78	hyperbilirubinemia	hyperbilirubinemia	X
american_scientific_journal-766	86	79	variable	variable	ADJ
american_scientific_journal-766	86	80	mitochondrial	mitochondrial	ADJ
american_scientific_journal-766	86	81	nuclear	nuclear	ADJ
american_scientific_journal-766	86	82	interactions	interaction	NOUN
american_scientific_journal-766	86	83	variable	variable	ADJ
american_scientific_journal-766	86	84	variable	variable	ADJ
american_scientific_journal-766	86	85	agents	agent	NOUN
american_scientific_journal-766	86	86	approved	approve	VERB
american_scientific_journal-766	86	87	telaprevir	telaprevir	PROPN
american_scientific_journal-766	86	88	,	,	PUNCT
american_scientific_journal-766	86	89	boceprevir	boceprevir	NOUN
american_scientific_journal-766	86	90	,	,	PUNCT
american_scientific_journal-766	86	91	simeprevir	simeprevir	PROPN
american_scientific_journal-766	86	92	sofosbuvir	sofosbuvir	VERB
american_scientific_journal-766	86	93	none	none	NOUN
american_scientific_journal-766	86	94	none	none	NOUN
american_scientific_journal-766	86	95	examples	example	NOUN
american_scientific_journal-766	86	96	in	in	ADP
american_scientific_journal-766	86	97	pipeline	pipeline	NOUN
american_scientific_journal-766	86	98	faldaprevir	faldaprevir	PROPN
american_scientific_journal-766	86	99	(	(	PUNCT
american_scientific_journal-766	86	100	bi-201335	bi-201335	NOUN
american_scientific_journal-766	86	101	)	)	PUNCT
american_scientific_journal-766	86	102	mk-5172	mk-5172	NOUN
american_scientific_journal-766	86	103	danoprevir	danoprevir	PROPN
american_scientific_journal-766	86	104	(	(	PUNCT
american_scientific_journal-766	86	105	rg7227	rg7227	PROPN
american_scientific_journal-766	86	106	/	/	SYM
american_scientific_journal-766	86	107	itmn-191	itmn-191	NOUN
american_scientific_journal-766	86	108	)	)	PUNCT
american_scientific_journal-766	87	1	veruprevir	veruprevir	NOUN
american_scientific_journal-766	87	2	(	(	PUNCT
american_scientific_journal-766	87	3	abt-450	abt-450	PROPN
american_scientific_journal-766	87	4	/	/	SYM
american_scientific_journal-766	87	5	r	r	NOUN
american_scientific_journal-766	87	6	)	)	PUNCT
american_scientific_journal-766	87	7	vaniprevir	vaniprevir	PROPN
american_scientific_journal-766	87	8	-	-	PUNCT
american_scientific_journal-766	87	9	mk-7009	mk-7009	NOUN
american_scientific_journal-766	87	10	vx-135	vx-135	PROPN
american_scientific_journal-766	87	11	mercitabine	mercitabine	NOUN
american_scientific_journal-766	87	12	abt-072	abt-072	NOUN
american_scientific_journal-766	87	13	dasabuvir	dasabuvir	PROPN
american_scientific_journal-766	87	14	(	(	PUNCT
american_scientific_journal-766	87	15	abt-333	abt-333	ADJ
american_scientific_journal-766	87	16	)	)	PUNCT
american_scientific_journal-766	87	17	bms-791325	bms-791325	NOUN
american_scientific_journal-766	88	1	daclatsavir	daclatsavir	PROPN
american_scientific_journal-766	88	2	(	(	PUNCT
american_scientific_journal-766	88	3	bms790052	bms790052	PROPN
american_scientific_journal-766	88	4	)	)	PUNCT
american_scientific_journal-766	88	5	ledipsavir	ledipsavir	PROPN
american_scientific_journal-766	88	6	(	(	PUNCT
american_scientific_journal-766	88	7	gs5885	gs5885	PROPN
american_scientific_journal-766	88	8	)	)	PUNCT
american_scientific_journal-766	88	9	samatasvir	samatasvir	NOUN
american_scientific_journal-766	88	10	(	(	PUNCT
american_scientific_journal-766	88	11	idx21437	idx21437	ADJ
american_scientific_journal-766	88	12	)	)	PUNCT
american_scientific_journal-766	88	13	ombitasvir	ombitasvir	PROPN
american_scientific_journal-766	88	14	(	(	PUNCT
american_scientific_journal-766	88	15	abt267	abt267	ADJ
american_scientific_journal-766	88	16	)	)	PUNCT
american_scientific_journal-766	88	17	abbreviations	abbreviation	NOUN
american_scientific_journal-766	88	18	:	:	PUNCT
american_scientific_journal-766	88	19	gt	gt	PROPN
american_scientific_journal-766	88	20	,	,	PUNCT
american_scientific_journal-766	88	21	genotype	genotype	NOUN
american_scientific_journal-766	88	22	;	;	PUNCT
american_scientific_journal-766	88	23	nis	nis	NOUN
american_scientific_journal-766	88	24	,	,	PUNCT
american_scientific_journal-766	88	25	nucleotide	nucleotide	ADJ
american_scientific_journal-766	88	26	polymerase	polymerase	NOUN
american_scientific_journal-766	88	27	inhibitors	inhibitor	NOUN
american_scientific_journal-766	88	28	;	;	PUNCT
american_scientific_journal-766	88	29	nnis	nnis	PROPN
american_scientific_journal-766	88	30	,	,	PUNCT
american_scientific_journal-766	88	31	non	non	ADJ
american_scientific_journal-766	88	32	-	-	ADJ
american_scientific_journal-766	88	33	nucleoside	nucleoside	ADJ
american_scientific_journal-766	88	34	inhibitors	inhibitor	NOUN
american_scientific_journal-766	88	35	;	;	PUNCT
american_scientific_journal-766	88	36	ns3/4a	ns3/4a	NUM
american_scientific_journal-766	88	37	5	5	NUM
american_scientific_journal-766	88	38	american	american	ADJ
american_scientific_journal-766	88	39	scientific	scientific	ADJ
american_scientific_journal-766	88	40	research	research	NOUN
american_scientific_journal-766	88	41	journal	journal	NOUN
american_scientific_journal-766	88	42	for	for	ADP
american_scientific_journal-766	88	43	engineering	engineering	NOUN
american_scientific_journal-766	88	44	,	,	PUNCT
american_scientific_journal-766	88	45	technology	technology	NOUN
american_scientific_journal-766	88	46	,	,	PUNCT
american_scientific_journal-766	88	47	and	and	CCONJ
american_scientific_journal-766	88	48	sciences	science	NOUN
american_scientific_journal-766	88	49	(	(	PUNCT
american_scientific_journal-766	88	50	asrjets	asrjet	NOUN
american_scientific_journal-766	88	51	)	)	PUNCT
american_scientific_journal-766	88	52	(	(	PUNCT
american_scientific_journal-766	88	53	2015	2015	NUM
american_scientific_journal-766	88	54	)	)	PUNCT
american_scientific_journal-766	88	55	volume	volume	NOUN
american_scientific_journal-766	88	56	13	13	NUM
american_scientific_journal-766	88	57	,	,	PUNCT
american_scientific_journal-766	88	58	no	no	DET
american_scientific_journal-766	88	59	1	1	NUM
american_scientific_journal-766	88	60	,	,	PUNCT
american_scientific_journal-766	88	61	pp	pp	ADV
american_scientific_journal-766	88	62	1	1	NUM
american_scientific_journal-766	88	63	-	-	SYM
american_scientific_journal-766	88	64	23	23	NUM
american_scientific_journal-766	88	65	protease	protease	NOUN
american_scientific_journal-766	88	66	inhibitors	inhibitor	NOUN
american_scientific_journal-766	88	67	.	.	PUNCT
american_scientific_journal-766	89	1	2.2.1	2.2.1	NUM
american_scientific_journal-766	89	2	.	.	X
american_scientific_journal-766	89	3	ns3/4a	ns3/4a	NOUN
american_scientific_journal-766	89	4	protease	protease	NOUN
american_scientific_journal-766	89	5	inhibitors	inhibitor	VERB
american_scientific_journal-766	89	6	the	the	DET
american_scientific_journal-766	89	7	ns3	ns3	NOUN
american_scientific_journal-766	89	8	protease	protease	NOUN
american_scientific_journal-766	89	9	is	be	AUX
american_scientific_journal-766	89	10	an	an	DET
american_scientific_journal-766	89	11	enzyme	enzyme	NOUN
american_scientific_journal-766	89	12	that	that	PRON
american_scientific_journal-766	89	13	catalyzes	catalyze	VERB
american_scientific_journal-766	89	14	the	the	DET
american_scientific_journal-766	89	15	post	post	ADJ
american_scientific_journal-766	89	16	-	-	ADJ
american_scientific_journal-766	89	17	transcriptional	transcriptional	ADJ
american_scientific_journal-766	89	18	processing	processing	NOUN
american_scientific_journal-766	89	19	of	of	ADP
american_scientific_journal-766	89	20	proteins	protein	NOUN
american_scientific_journal-766	89	21	important	important	ADJ
american_scientific_journal-766	89	22	for	for	ADP
american_scientific_journal-766	89	23	viral	viral	ADJ
american_scientific_journal-766	89	24	replication	replication	NOUN
american_scientific_journal-766	89	25	.	.	PUNCT
american_scientific_journal-766	90	1	ns4a	ns4a	NOUN
american_scientific_journal-766	90	2	is	be	AUX
american_scientific_journal-766	90	3	a	a	DET
american_scientific_journal-766	90	4	cofactor	cofactor	NOUN
american_scientific_journal-766	90	5	that	that	PRON
american_scientific_journal-766	90	6	works	work	VERB
american_scientific_journal-766	90	7	with	with	ADP
american_scientific_journal-766	90	8	ns3	ns3	NOUN
american_scientific_journal-766	90	9	to	to	PART
american_scientific_journal-766	90	10	expedite	expedite	VERB
american_scientific_journal-766	90	11	this	this	DET
american_scientific_journal-766	90	12	process	process	NOUN
american_scientific_journal-766	90	13	.	.	PUNCT
american_scientific_journal-766	91	1	the	the	DET
american_scientific_journal-766	91	2	serine	serine	ADJ
american_scientific_journal-766	91	3	protease	protease	NOUN
american_scientific_journal-766	91	4	inhibitors	inhibitor	NOUN
american_scientific_journal-766	91	5	telaprevir	telaprevir	PRON
american_scientific_journal-766	91	6	is	be	AUX
american_scientific_journal-766	91	7	a	a	DET
american_scientific_journal-766	91	8	linear	linear	ADJ
american_scientific_journal-766	91	9	peptidomimetic	peptidomimetic	ADJ
american_scientific_journal-766	91	10	hcv	hcv	NOUN
american_scientific_journal-766	91	11	ns3/4a	ns3/4a	NOUN
american_scientific_journal-766	91	12	serine	serine	NOUN
american_scientific_journal-766	91	13	protease	protease	NOUN
american_scientific_journal-766	91	14	inhibitor	inhibitor	NOUN
american_scientific_journal-766	91	15	,	,	PUNCT
american_scientific_journal-766	91	16	and	and	CCONJ
american_scientific_journal-766	91	17	boceprevir	boceprevir	NOUN
american_scientific_journal-766	91	18	is	be	AUX
american_scientific_journal-766	91	19	a	a	DET
american_scientific_journal-766	91	20	protease	protease	NOUN
american_scientific_journal-766	91	21	inhibitor	inhibitor	NOUN
american_scientific_journal-766	91	22	that	that	PRON
american_scientific_journal-766	91	23	binds	bind	VERB
american_scientific_journal-766	91	24	to	to	ADP
american_scientific_journal-766	91	25	the	the	DET
american_scientific_journal-766	91	26	hcv	hcv	PROPN
american_scientific_journal-766	91	27	ns3	ns3	X
american_scientific_journal-766	91	28	active	active	ADJ
american_scientific_journal-766	91	29	site	site	NOUN
american_scientific_journal-766	91	30	[	[	X
american_scientific_journal-766	91	31	35	35	NUM
american_scientific_journal-766	91	32	]	]	PUNCT
american_scientific_journal-766	91	33	.	.	PUNCT
american_scientific_journal-766	92	1	newer	new	ADJ
american_scientific_journal-766	92	2	,	,	PUNCT
american_scientific_journal-766	92	3	ns3/4a	ns3/4a	NOUN
american_scientific_journal-766	92	4	inhibitors	inhibitor	NOUN
american_scientific_journal-766	92	5	under	under	ADP
american_scientific_journal-766	92	6	development	development	NOUN
american_scientific_journal-766	92	7	are	be	AUX
american_scientific_journal-766	92	8	mainly	mainly	ADV
american_scientific_journal-766	92	9	macrocyclic	macrocyclic	NOUN
american_scientific_journal-766	92	10	compounds	compound	NOUN
american_scientific_journal-766	92	11	(	(	PUNCT
american_scientific_journal-766	92	12	simeprevir	simeprevir	PROPN
american_scientific_journal-766	92	13	-	-	PUNCT
american_scientific_journal-766	92	14	tmc-435	tmc-435	NOUN
american_scientific_journal-766	92	15	,	,	PUNCT
american_scientific_journal-766	92	16	danoprevir	danoprevir	PROPN
american_scientific_journal-766	92	17	-	-	PUNCT
american_scientific_journal-766	92	18	r7227	r7227	PROPN
american_scientific_journal-766	92	19	,	,	PUNCT
american_scientific_journal-766	92	20	and	and	CCONJ
american_scientific_journal-766	92	21	vaniprevir	vaniprevir	PROPN
american_scientific_journal-766	92	22	-	-	PUNCT
american_scientific_journal-766	92	23	mk-7009	mk-7009	NOUN
american_scientific_journal-766	92	24	)	)	PUNCT
american_scientific_journal-766	92	25	and	and	CCONJ
american_scientific_journal-766	92	26	the	the	DET
american_scientific_journal-766	92	27	linear	linear	ADJ
american_scientific_journal-766	92	28	asunaprevir	asunaprevir	PROPN
american_scientific_journal-766	92	29	(	(	PUNCT
american_scientific_journal-766	92	30	bms-650032	bms-650032	ADJ
american_scientific_journal-766	92	31	)	)	PUNCT
american_scientific_journal-766	92	32	.	.	PUNCT
american_scientific_journal-766	93	1	in	in	ADP
american_scientific_journal-766	93	2	addition	addition	NOUN
american_scientific_journal-766	93	3	,	,	PUNCT
american_scientific_journal-766	93	4	newer	new	ADJ
american_scientific_journal-766	93	5	first	first	ADJ
american_scientific_journal-766	93	6	generation	generation	NOUN
american_scientific_journal-766	93	7	as	as	ADV
american_scientific_journal-766	93	8	well	well	ADV
american_scientific_journal-766	93	9	as	as	ADP
american_scientific_journal-766	93	10	secondand	secondand	NOUN
american_scientific_journal-766	93	11	third	third	ADJ
american_scientific_journal-766	93	12	-	-	PUNCT
american_scientific_journal-766	93	13	generation	generation	NOUN
american_scientific_journal-766	93	14	ns3/4a	ns3/4a	NOUN
american_scientific_journal-766	93	15	inhibitors	inhibitor	NOUN
american_scientific_journal-766	93	16	(	(	PUNCT
american_scientific_journal-766	93	17	faldaprevir	faldaprevir	NOUN
american_scientific_journal-766	93	18	-	-	PUNCT
american_scientific_journal-766	93	19	bi	bi	PROPN
american_scientific_journal-766	93	20	201335	201335	NUM
american_scientific_journal-766	93	21	,	,	PUNCT
american_scientific_journal-766	93	22	gs-9256	gs-9256	PROPN
american_scientific_journal-766	93	23	,	,	PUNCT
american_scientific_journal-766	93	24	abt-450	abt-450	NOUN
american_scientific_journal-766	93	25	,	,	PUNCT
american_scientific_journal-766	93	26	etc	etc	X
american_scientific_journal-766	93	27	.	.	X
american_scientific_journal-766	93	28	)	)	PUNCT
american_scientific_journal-766	93	29	are	be	AUX
american_scientific_journal-766	93	30	expected	expect	VERB
american_scientific_journal-766	93	31	to	to	PART
american_scientific_journal-766	93	32	have	have	VERB
american_scientific_journal-766	93	33	better	well	ADJ
american_scientific_journal-766	93	34	pharmacokinetics	pharmacokinetic	NOUN
american_scientific_journal-766	93	35	for	for	ADP
american_scientific_journal-766	93	36	once	once	ADV
american_scientific_journal-766	93	37	daily	daily	ADJ
american_scientific_journal-766	93	38	dosage	dosage	NOUN
american_scientific_journal-766	93	39	,	,	PUNCT
american_scientific_journal-766	93	40	less	less	ADV
american_scientific_journal-766	93	41	complicated	complicated	ADJ
american_scientific_journal-766	93	42	treatment	treatment	NOUN
american_scientific_journal-766	93	43	algorithms	algorithm	NOUN
american_scientific_journal-766	93	44	and	and	CCONJ
american_scientific_journal-766	93	45	less	less	ADJ
american_scientific_journal-766	93	46	side	side	ADJ
american_scientific_journal-766	93	47	effects	effect	NOUN
american_scientific_journal-766	93	48	compared	compare	VERB
american_scientific_journal-766	93	49	to	to	ADP
american_scientific_journal-766	93	50	boceprevir	boceprevir	PROPN
american_scientific_journal-766	93	51	and	and	CCONJ
american_scientific_journal-766	93	52	telaprevir	telaprevir	PRON
american_scientific_journal-766	94	1	[	[	X
american_scientific_journal-766	94	2	18	18	NUM
american_scientific_journal-766	94	3	]	]	PUNCT
american_scientific_journal-766	94	4	(	(	PUNCT
american_scientific_journal-766	94	5	table	table	NOUN
american_scientific_journal-766	94	6	1	1	NUM
american_scientific_journal-766	94	7	)	)	PUNCT
american_scientific_journal-766	94	8	.	.	PUNCT
american_scientific_journal-766	95	1	2.2.1.1	2.2.1.1	NUM
american_scientific_journal-766	95	2	.	.	PUNCT
american_scientific_journal-766	96	1	telaprevir	telaprevir	PROPN
american_scientific_journal-766	96	2	and	and	CCONJ
american_scientific_journal-766	96	3	boceprevir	boceprevir	VERB
american_scientific_journal-766	96	4	two	two	NUM
american_scientific_journal-766	96	5	first	first	ADJ
american_scientific_journal-766	96	6	-	-	PUNCT
american_scientific_journal-766	96	7	generation	generation	NOUN
american_scientific_journal-766	96	8	,	,	PUNCT
american_scientific_journal-766	96	9	linear	linear	ADJ
american_scientific_journal-766	96	10	ns3/4a	ns3/4a	ADV
american_scientific_journal-766	96	11	pis	pis	NOUN
american_scientific_journal-766	96	12	,	,	PUNCT
american_scientific_journal-766	96	13	boceprevir	boceprevir	NOUN
american_scientific_journal-766	96	14	and	and	CCONJ
american_scientific_journal-766	96	15	telaprevir	telaprevir	PROPN
american_scientific_journal-766	96	16	,	,	PUNCT
american_scientific_journal-766	96	17	were	be	AUX
american_scientific_journal-766	96	18	approved	approve	VERB
american_scientific_journal-766	96	19	in	in	ADP
american_scientific_journal-766	96	20	the	the	DET
american_scientific_journal-766	96	21	usa	usa	PROPN
american_scientific_journal-766	96	22	and	and	CCONJ
american_scientific_journal-766	96	23	europe	europe	PROPN
american_scientific_journal-766	96	24	in	in	ADP
american_scientific_journal-766	96	25	2011	2011	NUM
american_scientific_journal-766	96	26	for	for	ADP
american_scientific_journal-766	96	27	clinical	clinical	ADJ
american_scientific_journal-766	96	28	use	use	NOUN
american_scientific_journal-766	96	29	in	in	ADP
american_scientific_journal-766	96	30	patients	patient	NOUN
american_scientific_journal-766	96	31	with	with	ADP
american_scientific_journal-766	96	32	genotype	genotype	NOUN
american_scientific_journal-766	96	33	1	1	NUM
american_scientific_journal-766	96	34	,	,	PUNCT
american_scientific_journal-766	96	35	while	while	SCONJ
american_scientific_journal-766	96	36	numerous	numerous	ADJ
american_scientific_journal-766	96	37	new	new	ADJ
american_scientific_journal-766	96	38	ns3/4	ns3/4	PROPN
american_scientific_journal-766	96	39	pis	pis	NOUN
american_scientific_journal-766	96	40	are	be	AUX
american_scientific_journal-766	96	41	currently	currently	ADV
american_scientific_journal-766	96	42	under	under	ADP
american_scientific_journal-766	96	43	evaluation	evaluation	NOUN
american_scientific_journal-766	96	44	in	in	ADP
american_scientific_journal-766	96	45	clinical	clinical	ADJ
american_scientific_journal-766	96	46	trials	trial	NOUN
american_scientific_journal-766	96	47	.	.	PUNCT
american_scientific_journal-766	97	1	however	however	ADV
american_scientific_journal-766	97	2	,	,	PUNCT
american_scientific_journal-766	97	3	these	these	DET
american_scientific_journal-766	97	4	first	first	ADJ
american_scientific_journal-766	97	5	generation	generation	NOUN
american_scientific_journal-766	97	6	daas	daas	NOUN
american_scientific_journal-766	97	7	have	have	VERB
american_scientific_journal-766	97	8	a	a	DET
american_scientific_journal-766	97	9	low	low	ADJ
american_scientific_journal-766	97	10	genetic	genetic	ADJ
american_scientific_journal-766	97	11	barrier	barrier	NOUN
american_scientific_journal-766	97	12	to	to	ADP
american_scientific_journal-766	97	13	resistance	resistance	NOUN
american_scientific_journal-766	97	14	,	,	PUNCT
american_scientific_journal-766	97	15	their	their	PRON
american_scientific_journal-766	97	16	efficacy	efficacy	NOUN
american_scientific_journal-766	97	17	is	be	AUX
american_scientific_journal-766	97	18	limited	limit	VERB
american_scientific_journal-766	97	19	to	to	PART
american_scientific_journal-766	97	20	hcv	hcv	VERB
american_scientific_journal-766	97	21	genotype	genotype	NOUN
american_scientific_journal-766	97	22	1	1	NUM
american_scientific_journal-766	97	23	and	and	CCONJ
american_scientific_journal-766	97	24	co	co	NOUN
american_scientific_journal-766	97	25	-	-	NOUN
american_scientific_journal-766	97	26	administration	administration	NOUN
american_scientific_journal-766	97	27	of	of	ADP
american_scientific_journal-766	97	28	peg	peg	NOUN
american_scientific_journal-766	97	29	-	-	PUNCT
american_scientific_journal-766	97	30	ifn	ifn	PROPN
american_scientific_journal-766	97	31	and	and	CCONJ
american_scientific_journal-766	97	32	rbv	rbv	NOUN
american_scientific_journal-766	97	33	is	be	AUX
american_scientific_journal-766	97	34	needed	need	VERB
american_scientific_journal-766	97	35	.	.	PUNCT
american_scientific_journal-766	98	1	in	in	ADP
american_scientific_journal-766	98	2	addition	addition	NOUN
american_scientific_journal-766	98	3	,	,	PUNCT
american_scientific_journal-766	98	4	the	the	DET
american_scientific_journal-766	98	5	triple	triple	ADJ
american_scientific_journal-766	98	6	regimens	regimen	NOUN
american_scientific_journal-766	98	7	are	be	AUX
american_scientific_journal-766	98	8	associated	associate	VERB
american_scientific_journal-766	98	9	with	with	ADP
american_scientific_journal-766	98	10	unfavorable	unfavorable	ADJ
american_scientific_journal-766	98	11	tolerance	tolerance	NOUN
american_scientific_journal-766	98	12	and	and	CCONJ
american_scientific_journal-766	98	13	safety	safety	NOUN
american_scientific_journal-766	98	14	profiles	profile	NOUN
american_scientific_journal-766	98	15	,	,	PUNCT
american_scientific_journal-766	98	16	particularly	particularly	ADV
american_scientific_journal-766	98	17	in	in	ADP
american_scientific_journal-766	98	18	patients	patient	NOUN
american_scientific_journal-766	98	19	with	with	ADP
american_scientific_journal-766	98	20	underlying	underlie	VERB
american_scientific_journal-766	98	21	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	98	22	[	[	X
american_scientific_journal-766	98	23	32	32	NUM
american_scientific_journal-766	98	24	]	]	PUNCT
american_scientific_journal-766	98	25	.	.	PUNCT
american_scientific_journal-766	99	1	2.2.1.2	2.2.1.2	X
american_scientific_journal-766	99	2	.	.	PROPN
american_scientific_journal-766	99	3	simeprevir	simeprevir	PROPN
american_scientific_journal-766	99	4	simeprevir	simeprevir	PROPN
american_scientific_journal-766	99	5	(	(	PUNCT
american_scientific_journal-766	99	6	formerly	formerly	ADV
american_scientific_journal-766	99	7	tmc435	tmc435	NOUN
american_scientific_journal-766	99	8	;	;	PUNCT
american_scientific_journal-766	99	9	trade	trade	NOUN
american_scientific_journal-766	99	10	name	name	NOUN
american_scientific_journal-766	99	11	olysio	olysio	PROPN
american_scientific_journal-766	99	12	)	)	PUNCT
american_scientific_journal-766	99	13	is	be	AUX
american_scientific_journal-766	99	14	a	a	DET
american_scientific_journal-766	99	15	new	new	ADJ
american_scientific_journal-766	99	16	direct	direct	ADJ
american_scientific_journal-766	99	17	acting	act	VERB
american_scientific_journal-766	99	18	antiviral	antiviral	ADJ
american_scientific_journal-766	99	19	drug	drug	NOUN
american_scientific_journal-766	99	20	and	and	CCONJ
american_scientific_journal-766	99	21	a	a	DET
american_scientific_journal-766	99	22	second	second	ADJ
american_scientific_journal-766	99	23	generation	generation	NOUN
american_scientific_journal-766	99	24	ns3/4a	ns3/4a	NOUN
american_scientific_journal-766	99	25	serine	serine	ADJ
american_scientific_journal-766	99	26	protease	protease	NOUN
american_scientific_journal-766	99	27	inhibitor	inhibitor	NOUN
american_scientific_journal-766	99	28	.	.	PUNCT
american_scientific_journal-766	100	1	food	food	NOUN
american_scientific_journal-766	100	2	and	and	CCONJ
american_scientific_journal-766	100	3	drug	drug	PROPN
american_scientific_journal-766	100	4	administration	administration	PROPN
american_scientific_journal-766	100	5	(	(	PUNCT
american_scientific_journal-766	100	6	fda	fda	PROPN
american_scientific_journal-766	100	7	)	)	PUNCT
american_scientific_journal-766	100	8	has	have	AUX
american_scientific_journal-766	100	9	approved	approve	VERB
american_scientific_journal-766	100	10	olysio	olysio	NOUN
american_scientific_journal-766	100	11	(	(	PUNCT
american_scientific_journal-766	100	12	simeprevir	simeprevir	PROPN
american_scientific_journal-766	100	13	)	)	PUNCT
american_scientific_journal-766	100	14	,	,	PUNCT
american_scientific_journal-766	100	15	a	a	DET
american_scientific_journal-766	100	16	hepatitis	hepatitis	NOUN
american_scientific_journal-766	100	17	c	c	PROPN
american_scientific_journal-766	100	18	virus	virus	NOUN
american_scientific_journal-766	100	19	(	(	PUNCT
american_scientific_journal-766	100	20	hcv	hcv	PROPN
american_scientific_journal-766	100	21	)	)	PUNCT
american_scientific_journal-766	100	22	ns3/4a	ns3/4a	NOUN
american_scientific_journal-766	100	23	protease	protease	NOUN
american_scientific_journal-766	100	24	inhibitor	inhibitor	NOUN
american_scientific_journal-766	100	25	,	,	PUNCT
american_scientific_journal-766	100	26	in	in	ADP
american_scientific_journal-766	100	27	combination	combination	NOUN
american_scientific_journal-766	100	28	with	with	ADP
american_scientific_journal-766	100	29	sofosbuvir	sofosbuvir	NOUN
american_scientific_journal-766	100	30	as	as	ADP
american_scientific_journal-766	100	31	an	an	DET
american_scientific_journal-766	100	32	all	all	ADV
american_scientific_journal-766	100	33	-	-	PUNCT
american_scientific_journal-766	100	34	oral	oral	ADJ
american_scientific_journal-766	100	35	,	,	PUNCT
american_scientific_journal-766	100	36	interferonand	interferonand	PROPN
american_scientific_journal-766	100	37	ribavirin	ribavirin	NOUN
american_scientific_journal-766	100	38	-	-	PUNCT
american_scientific_journal-766	100	39	free	free	ADJ
american_scientific_journal-766	100	40	treatment	treatment	NOUN
american_scientific_journal-766	100	41	option	option	NOUN
american_scientific_journal-766	100	42	for	for	ADP
american_scientific_journal-766	100	43	genotype	genotype	NOUN
american_scientific_journal-766	100	44	1	1	NUM
american_scientific_journal-766	100	45	chronic	chronic	ADJ
american_scientific_journal-766	100	46	hepatitis	hepatitis	NOUN
american_scientific_journal-766	100	47	c	c	PROPN
american_scientific_journal-766	100	48	(	(	PUNCT
american_scientific_journal-766	100	49	chc	chc	PROPN
american_scientific_journal-766	100	50	)	)	PUNCT
american_scientific_journal-766	100	51	infection	infection	NOUN
american_scientific_journal-766	100	52	in	in	ADP
american_scientific_journal-766	100	53	adult	adult	NOUN
american_scientific_journal-766	100	54	patients	patient	NOUN
american_scientific_journal-766	100	55	as	as	ADP
american_scientific_journal-766	100	56	part	part	NOUN
american_scientific_journal-766	100	57	of	of	ADP
american_scientific_journal-766	100	58	a	a	DET
american_scientific_journal-766	100	59	combination	combination	NOUN
american_scientific_journal-766	100	60	antiviral	antiviral	ADJ
american_scientific_journal-766	100	61	treatment	treatment	NOUN
american_scientific_journal-766	100	62	regimen	regiman	NOUN
american_scientific_journal-766	100	63	.	.	PUNCT
american_scientific_journal-766	101	1	it	it	PRON
american_scientific_journal-766	101	2	was	be	AUX
american_scientific_journal-766	101	3	introduced	introduce	VERB
american_scientific_journal-766	101	4	by	by	ADP
american_scientific_journal-766	101	5	janssen	janssen	PROPN
american_scientific_journal-766	101	6	and	and	CCONJ
american_scientific_journal-766	101	7	medivir	medivir	PROPN
american_scientific_journal-766	101	8	for	for	ADP
american_scientific_journal-766	101	9	the	the	DET
american_scientific_journal-766	101	10	oral	oral	ADJ
american_scientific_journal-766	101	11	treatment	treatment	NOUN
american_scientific_journal-766	101	12	of	of	ADP
american_scientific_journal-766	101	13	patients	patient	NOUN
american_scientific_journal-766	101	14	with	with	ADP
american_scientific_journal-766	101	15	genotype	genotype	NOUN
american_scientific_journal-766	101	16	1	1	NUM
american_scientific_journal-766	101	17	and/or	and/or	CCONJ
american_scientific_journal-766	101	18	genotype	genotype	NOUN
american_scientific_journal-766	101	19	4	4	NUM
american_scientific_journal-766	101	20	chronic	chronic	ADJ
american_scientific_journal-766	101	21	hcv	hcv	NOUN
american_scientific_journal-766	101	22	infections	infection	NOUN
american_scientific_journal-766	101	23	[	[	X
american_scientific_journal-766	101	24	36	36	NUM
american_scientific_journal-766	101	25	]	]	PUNCT
american_scientific_journal-766	101	26	.	.	PUNCT
american_scientific_journal-766	102	1	in	in	ADP
american_scientific_journal-766	102	2	vitro	vitro	X
american_scientific_journal-766	102	3	,	,	PUNCT
american_scientific_journal-766	102	4	it	it	PRON
american_scientific_journal-766	102	5	is	be	AUX
american_scientific_journal-766	102	6	active	active	ADJ
american_scientific_journal-766	102	7	against	against	ADP
american_scientific_journal-766	102	8	all	all	DET
american_scientific_journal-766	102	9	six	six	NUM
american_scientific_journal-766	102	10	genotypes	genotype	NOUN
american_scientific_journal-766	102	11	with	with	ADP
american_scientific_journal-766	102	12	lesser	less	ADJ
american_scientific_journal-766	102	13	efficacy	efficacy	NOUN
american_scientific_journal-766	102	14	against	against	ADP
american_scientific_journal-766	102	15	genotype	genotype	NOUN
american_scientific_journal-766	102	16	3a	3a	NUM
american_scientific_journal-766	102	17	[	[	X
american_scientific_journal-766	102	18	37	37	NUM
american_scientific_journal-766	102	19	]	]	PUNCT
american_scientific_journal-766	102	20	.	.	PUNCT
american_scientific_journal-766	103	1	simeprevir	simeprevir	PROPN
american_scientific_journal-766	103	2	(	(	PUNCT
american_scientific_journal-766	103	3	smv	smv	PROPN
american_scientific_journal-766	103	4	)	)	PUNCT
american_scientific_journal-766	103	5	prevents	prevent	VERB
american_scientific_journal-766	103	6	viral	viral	ADJ
american_scientific_journal-766	103	7	maturation	maturation	NOUN
american_scientific_journal-766	103	8	through	through	ADP
american_scientific_journal-766	103	9	inhibition	inhibition	NOUN
american_scientific_journal-766	103	10	of	of	ADP
american_scientific_journal-766	103	11	protein	protein	NOUN
american_scientific_journal-766	103	12	synthesis	synthesis	NOUN
american_scientific_journal-766	103	13	.	.	PUNCT
american_scientific_journal-766	104	1	smv	smv	NOUN
american_scientific_journal-766	104	2	is	be	AUX
american_scientific_journal-766	104	3	also	also	ADV
american_scientific_journal-766	104	4	a	a	DET
american_scientific_journal-766	104	5	substrate	substrate	NOUN
american_scientific_journal-766	104	6	and	and	CCONJ
american_scientific_journal-766	104	7	mild	mild	ADJ
american_scientific_journal-766	104	8	inhibitor	inhibitor	NOUN
american_scientific_journal-766	104	9	of	of	ADP
american_scientific_journal-766	104	10	p	p	NOUN
american_scientific_journal-766	104	11	-	-	PUNCT
american_scientific_journal-766	104	12	glycoprotein	glycoprotein	NOUN
american_scientific_journal-766	104	13	which	which	PRON
american_scientific_journal-766	104	14	may	may	AUX
american_scientific_journal-766	104	15	help	help	VERB
american_scientific_journal-766	104	16	predict	predict	VERB
american_scientific_journal-766	104	17	other	other	ADJ
american_scientific_journal-766	104	18	drug	drug	NOUN
american_scientific_journal-766	104	19	interactions	interaction	NOUN
american_scientific_journal-766	104	20	[	[	X
american_scientific_journal-766	104	21	38	38	NUM
american_scientific_journal-766	104	22	]	]	PUNCT
american_scientific_journal-766	104	23	.	.	PUNCT
american_scientific_journal-766	105	1	smv	smv	NOUN
american_scientific_journal-766	105	2	is	be	AUX
american_scientific_journal-766	105	3	metabolized	metabolize	VERB
american_scientific_journal-766	105	4	mainly	mainly	ADV
american_scientific_journal-766	105	5	by	by	ADP
american_scientific_journal-766	105	6	the	the	DET
american_scientific_journal-766	105	7	cytochrome	cytochrome	NOUN
american_scientific_journal-766	105	8	p450	p450	PROPN
american_scientific_journal-766	105	9	3a	3a	NUM
american_scientific_journal-766	105	10	(	(	PUNCT
american_scientific_journal-766	105	11	cyp3a	cyp3a	NOUN
american_scientific_journal-766	105	12	)	)	PUNCT
american_scientific_journal-766	105	13	pathway	pathway	NOUN
american_scientific_journal-766	105	14	in	in	ADP
american_scientific_journal-766	105	15	the	the	DET
american_scientific_journal-766	105	16	liver	liver	NOUN
american_scientific_journal-766	105	17	and	and	CCONJ
american_scientific_journal-766	105	18	can	can	AUX
american_scientific_journal-766	105	19	cause	cause	VERB
american_scientific_journal-766	105	20	drug	drug	NOUN
american_scientific_journal-766	105	21	-	-	PUNCT
american_scientific_journal-766	105	22	drug	drug	NOUN
american_scientific_journal-766	105	23	interactions	interaction	NOUN
american_scientific_journal-766	105	24	with	with	ADP
american_scientific_journal-766	105	25	inhibitors	inhibitor	NOUN
american_scientific_journal-766	105	26	and	and	CCONJ
american_scientific_journal-766	105	27	inducers	inducer	NOUN
american_scientific_journal-766	105	28	of	of	ADP
american_scientific_journal-766	105	29	cyp3a	cyp3a	PROPN
american_scientific_journal-766	105	30	.	.	PUNCT
american_scientific_journal-766	106	1	the	the	DET
american_scientific_journal-766	106	2	all	all	ADV
american_scientific_journal-766	106	3	-	-	PUNCT
american_scientific_journal-766	106	4	oral	oral	ADJ
american_scientific_journal-766	106	5	,	,	PUNCT
american_scientific_journal-766	106	6	interferon	interferon	ADJ
american_scientific_journal-766	106	7	-	-	PUNCT
american_scientific_journal-766	106	8	free	free	ADJ
american_scientific_journal-766	106	9	treatment	treatment	NOUN
american_scientific_journal-766	106	10	regimen	regiman	NOUN
american_scientific_journal-766	106	11	with	with	ADP
american_scientific_journal-766	106	12	simeprevir	simeprevir	NOUN
american_scientific_journal-766	106	13	and	and	CCONJ
american_scientific_journal-766	106	14	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	106	15	resulted	result	VERB
american_scientific_journal-766	106	16	in	in	ADP
american_scientific_journal-766	106	17	an	an	DET
american_scientific_journal-766	106	18	overall	overall	ADJ
american_scientific_journal-766	106	19	svr12	svr12	ADJ
american_scientific_journal-766	106	20	rate	rate	NOUN
american_scientific_journal-766	106	21	of	of	ADP
american_scientific_journal-766	106	22	92	92	NUM
american_scientific_journal-766	106	23	%	%	NOUN
american_scientific_journal-766	106	24	,	,	PUNCT
american_scientific_journal-766	106	25	consistent	consistent	ADJ
american_scientific_journal-766	106	26	svr12	svr12	ADJ
american_scientific_journal-766	106	27	rates	rate	NOUN
american_scientific_journal-766	106	28	regardless	regardless	ADV
american_scientific_journal-766	106	29	of	of	ADP
american_scientific_journal-766	106	30	metavir	metavir	PROPN
american_scientific_journal-766	106	31	score	score	NOUN
american_scientific_journal-766	106	32	,	,	PUNCT
american_scientific_journal-766	106	33	and	and	CCONJ
american_scientific_journal-766	106	34	was	be	AUX
american_scientific_journal-766	106	35	an	an	DET
american_scientific_journal-766	106	36	effective	effective	ADJ
american_scientific_journal-766	106	37	and	and	CCONJ
american_scientific_journal-766	106	38	well	well	ADV
american_scientific_journal-766	106	39	-	-	PUNCT
american_scientific_journal-766	106	40	tolerated	tolerate	VERB
american_scientific_journal-766	106	41	therapeutic	therapeutic	ADJ
american_scientific_journal-766	106	42	regimen	regiman	NOUN
american_scientific_journal-766	106	43	in	in	ADP
american_scientific_journal-766	106	44	both	both	DET
american_scientific_journal-766	106	45	treatment	treatment	NOUN
american_scientific_journal-766	106	46	-	-	PUNCT
american_scientific_journal-766	106	47	naïve	naïve	ADJ
american_scientific_journal-766	106	48	and	and	CCONJ
american_scientific_journal-766	106	49	prior	prior	ADJ
american_scientific_journal-766	106	50	null	null	ADJ
american_scientific_journal-766	106	51	-	-	PUNCT
american_scientific_journal-766	106	52	responder	responder	NOUN
american_scientific_journal-766	106	53	patients	patient	NOUN
american_scientific_journal-766	106	54	[	[	X
american_scientific_journal-766	106	55	39	39	NUM
american_scientific_journal-766	106	56	]	]	PUNCT
american_scientific_journal-766	106	57	.	.	PUNCT
american_scientific_journal-766	107	1	moreover	moreover	ADV
american_scientific_journal-766	107	2	,	,	PUNCT
american_scientific_journal-766	107	3	simeprevir	simeprevir	NOUN
american_scientific_journal-766	107	4	proved	prove	VERB
american_scientific_journal-766	107	5	to	to	PART
american_scientific_journal-766	107	6	have	have	VERB
american_scientific_journal-766	107	7	several	several	ADJ
american_scientific_journal-766	107	8	advantages	advantage	NOUN
american_scientific_journal-766	107	9	such	such	ADJ
american_scientific_journal-766	107	10	as	as	ADP
american_scientific_journal-766	107	11	its	its	PRON
american_scientific_journal-766	107	12	high	high	ADJ
american_scientific_journal-766	107	13	efficacy	efficacy	NOUN
american_scientific_journal-766	107	14	,	,	PUNCT
american_scientific_journal-766	107	15	short	short	ADJ
american_scientific_journal-766	107	16	treatment	treatment	NOUN
american_scientific_journal-766	107	17	duration	duration	NOUN
american_scientific_journal-766	107	18	(	(	PUNCT
american_scientific_journal-766	107	19	12–24	12–24	NUM
american_scientific_journal-766	107	20	weeks	week	NOUN
american_scientific_journal-766	107	21	)	)	PUNCT
american_scientific_journal-766	107	22	,	,	PUNCT
american_scientific_journal-766	107	23	better	well	ADJ
american_scientific_journal-766	107	24	safety	safety	NOUN
american_scientific_journal-766	107	25	profile	profile	NOUN
american_scientific_journal-766	107	26	than	than	ADP
american_scientific_journal-766	107	27	first	first	ADJ
american_scientific_journal-766	107	28	generation	generation	NOUN
american_scientific_journal-766	107	29	drugs	drug	NOUN
american_scientific_journal-766	107	30	and	and	CCONJ
american_scientific_journal-766	107	31	the	the	DET
american_scientific_journal-766	107	32	decreased	decrease	VERB
american_scientific_journal-766	107	33	pill	pill	NOUN
american_scientific_journal-766	107	34	burden	burden	NOUN
american_scientific_journal-766	107	35	being	be	AUX
american_scientific_journal-766	107	36	taken	take	VERB
american_scientific_journal-766	107	37	once	once	ADV
american_scientific_journal-766	107	38	daily	daily	ADV
american_scientific_journal-766	107	39	[	[	X
american_scientific_journal-766	107	40	40	40	NUM
american_scientific_journal-766	107	41	]	]	PUNCT
american_scientific_journal-766	107	42	.	.	PUNCT
american_scientific_journal-766	108	1	6	6	NUM
american_scientific_journal-766	108	2	http://www.drugs.com/olysio.html	http://www.drugs.com/olysio.html	NOUN
american_scientific_journal-766	108	3	http://www.drugs.com/cdi/simeprevir.html	http://www.drugs.com/cdi/simeprevir.html	X
american_scientific_journal-766	108	4	http://www.drugs.com/cdi/sofosbuvir.html	http://www.drugs.com/cdi/sofosbuvir.html	NOUN
american_scientific_journal-766	109	1	american	american	PROPN
american_scientific_journal-766	109	2	scientific	scientific	ADJ
american_scientific_journal-766	109	3	research	research	PROPN
american_scientific_journal-766	109	4	journal	journal	NOUN
american_scientific_journal-766	109	5	for	for	ADP
american_scientific_journal-766	109	6	engineering	engineering	NOUN
american_scientific_journal-766	109	7	,	,	PUNCT
american_scientific_journal-766	109	8	technology	technology	NOUN
american_scientific_journal-766	109	9	,	,	PUNCT
american_scientific_journal-766	109	10	and	and	CCONJ
american_scientific_journal-766	109	11	sciences	science	NOUN
american_scientific_journal-766	109	12	(	(	PUNCT
american_scientific_journal-766	109	13	asrjets	asrjet	NOUN
american_scientific_journal-766	109	14	)	)	PUNCT
american_scientific_journal-766	109	15	(	(	PUNCT
american_scientific_journal-766	109	16	2015	2015	NUM
american_scientific_journal-766	109	17	)	)	PUNCT
american_scientific_journal-766	109	18	volume	volume	NOUN
american_scientific_journal-766	109	19	13	13	NUM
american_scientific_journal-766	109	20	,	,	PUNCT
american_scientific_journal-766	109	21	no	no	DET
american_scientific_journal-766	109	22	1	1	NUM
american_scientific_journal-766	109	23	,	,	PUNCT
american_scientific_journal-766	109	24	pp	pp	ADV
american_scientific_journal-766	109	25	1	1	NUM
american_scientific_journal-766	109	26	-	-	SYM
american_scientific_journal-766	109	27	23	23	NUM
american_scientific_journal-766	109	28	2.2.1.3	2.2.1.3	NUM
american_scientific_journal-766	109	29	.	.	PROPN
american_scientific_journal-766	109	30	faldaprevir	faldaprevir	PROPN
american_scientific_journal-766	109	31	;	;	PUNCT
american_scientific_journal-766	109	32	faldaprevir	faldaprevir	PROPN
american_scientific_journal-766	109	33	is	be	AUX
american_scientific_journal-766	109	34	a	a	DET
american_scientific_journal-766	109	35	second	second	ADJ
american_scientific_journal-766	109	36	-	-	PUNCT
american_scientific_journal-766	109	37	generation	generation	NOUN
american_scientific_journal-766	109	38	hcv	hcv	NOUN
american_scientific_journal-766	109	39	ns3/4a	ns3/4a	NUM
american_scientific_journal-766	109	40	protease	protease	NOUN
american_scientific_journal-766	109	41	inhibitor	inhibitor	NOUN
american_scientific_journal-766	109	42	with	with	ADP
american_scientific_journal-766	109	43	significant	significant	ADJ
american_scientific_journal-766	109	44	improvement	improvement	NOUN
american_scientific_journal-766	109	45	in	in	ADP
american_scientific_journal-766	109	46	potency	potency	NOUN
american_scientific_journal-766	109	47	and	and	CCONJ
american_scientific_journal-766	109	48	adverse	adverse	ADJ
american_scientific_journal-766	109	49	event	event	NOUN
american_scientific_journal-766	109	50	profile	profile	NOUN
american_scientific_journal-766	109	51	compared	compare	VERB
american_scientific_journal-766	109	52	with	with	ADP
american_scientific_journal-766	109	53	first	first	ADJ
american_scientific_journal-766	109	54	-	-	PUNCT
american_scientific_journal-766	109	55	generation	generation	NOUN
american_scientific_journal-766	109	56	protease	protease	NOUN
american_scientific_journal-766	109	57	inhibitors	inhibitor	NOUN
american_scientific_journal-766	109	58	.	.	PUNCT
american_scientific_journal-766	110	1	faldaprevir	faldaprevir	PROPN
american_scientific_journal-766	110	2	has	have	VERB
american_scientific_journal-766	110	3	an	an	DET
american_scientific_journal-766	110	4	acceptable	acceptable	ADJ
american_scientific_journal-766	110	5	tolerability	tolerability	NOUN
american_scientific_journal-766	110	6	and	and	CCONJ
american_scientific_journal-766	110	7	safety	safety	NOUN
american_scientific_journal-766	110	8	at	at	ADP
american_scientific_journal-766	110	9	all	all	DET
american_scientific_journal-766	110	10	dose	dose	NOUN
american_scientific_journal-766	110	11	levels	level	NOUN
american_scientific_journal-766	110	12	[	[	X
american_scientific_journal-766	110	13	41	41	NUM
american_scientific_journal-766	110	14	]	]	PUNCT
american_scientific_journal-766	110	15	.	.	PUNCT
american_scientific_journal-766	111	1	several	several	ADJ
american_scientific_journal-766	111	2	studies	study	NOUN
american_scientific_journal-766	111	3	used	use	VERB
american_scientific_journal-766	111	4	it	it	PRON
american_scientific_journal-766	111	5	with	with	ADP
american_scientific_journal-766	111	6	different	different	ADJ
american_scientific_journal-766	111	7	drug	drug	NOUN
american_scientific_journal-766	111	8	combinations	combination	NOUN
american_scientific_journal-766	111	9	.	.	PUNCT
american_scientific_journal-766	112	1	silenc1	silenc1	NOUN
american_scientific_journal-766	112	2	(	(	PUNCT
american_scientific_journal-766	112	3	for	for	ADP
american_scientific_journal-766	112	4	naïve	naïve	ADJ
american_scientific_journal-766	112	5	g1	g1	PROPN
american_scientific_journal-766	112	6	hcv	hcv	PROPN
american_scientific_journal-766	112	7	patients	patient	NOUN
american_scientific_journal-766	112	8	)	)	PUNCT
american_scientific_journal-766	112	9	and	and	CCONJ
american_scientific_journal-766	112	10	silen	silen	VERB
american_scientific_journal-766	112	11	-	-	PUNCT
american_scientific_journal-766	112	12	c2	c2	PROPN
american_scientific_journal-766	112	13	(	(	PUNCT
american_scientific_journal-766	112	14	for	for	ADP
american_scientific_journal-766	112	15	prior	prior	ADJ
american_scientific_journal-766	112	16	nonresponders	nonresponder	NOUN
american_scientific_journal-766	112	17	)	)	PUNCT
american_scientific_journal-766	112	18	were	be	AUX
american_scientific_journal-766	112	19	enrolled	enrol	VERB
american_scientific_journal-766	112	20	on	on	ADP
american_scientific_journal-766	112	21	429	429	NUM
american_scientific_journal-766	112	22	and	and	CCONJ
american_scientific_journal-766	112	23	290	290	NUM
american_scientific_journal-766	112	24	patients	patient	NOUN
american_scientific_journal-766	112	25	respectively	respectively	ADV
american_scientific_journal-766	112	26	.	.	PUNCT
american_scientific_journal-766	113	1	of	of	ADP
american_scientific_journal-766	113	2	interest	interest	NOUN
american_scientific_journal-766	113	3	,	,	PUNCT
american_scientific_journal-766	113	4	faldaprevir	faldaprevir	X
american_scientific_journal-766	113	5	in	in	ADP
american_scientific_journal-766	113	6	combination	combination	NOUN
american_scientific_journal-766	113	7	with	with	ADP
american_scientific_journal-766	113	8	pegylated	pegylated	ADJ
american_scientific_journal-766	113	9	interferon	interferon	NOUN
american_scientific_journal-766	113	10	and	and	CCONJ
american_scientific_journal-766	113	11	ribavirin	ribavirin	NOUN
american_scientific_journal-766	113	12	,	,	PUNCT
american_scientific_journal-766	113	13	and	and	CCONJ
american_scientific_journal-766	113	14	interferon	interferon	ADJ
american_scientific_journal-766	113	15	-	-	PUNCT
american_scientific_journal-766	113	16	free	free	ADJ
american_scientific_journal-766	113	17	treatment	treatment	NOUN
american_scientific_journal-766	113	18	with	with	ADP
american_scientific_journal-766	113	19	faldaprevir	faldaprevir	NOUN
american_scientific_journal-766	113	20	in	in	ADP
american_scientific_journal-766	113	21	combination	combination	NOUN
american_scientific_journal-766	113	22	with	with	ADP
american_scientific_journal-766	113	23	deleobuvir	deleobuvir	PROPN
american_scientific_journal-766	113	24	plus	plus	CCONJ
american_scientific_journal-766	113	25	ribavirin	ribavirin	NOUN
american_scientific_journal-766	113	26	provides	provide	VERB
american_scientific_journal-766	113	27	high	high	ADJ
american_scientific_journal-766	113	28	sustained	sustain	VERB
american_scientific_journal-766	113	29	virological	virological	ADJ
american_scientific_journal-766	113	30	response	response	NOUN
american_scientific_journal-766	113	31	rates	rate	NOUN
american_scientific_journal-766	113	32	for	for	ADP
american_scientific_journal-766	113	33	hcv	hcv	NOUN
american_scientific_journal-766	113	34	genotype	genotype	NOUN
american_scientific_journal-766	113	35	1	1	NUM
american_scientific_journal-766	113	36	infection	infection	NOUN
american_scientific_journal-766	113	37	%	%	NOUN
american_scientific_journal-766	113	38	respectively	respectively	ADV
american_scientific_journal-766	113	39	[	[	X
american_scientific_journal-766	113	40	42	42	NUM
american_scientific_journal-766	113	41	]	]	PUNCT
american_scientific_journal-766	113	42	.	.	PUNCT
american_scientific_journal-766	114	1	silen	silen	PROPN
american_scientific_journal-766	114	2	-	-	PUNCT
american_scientific_journal-766	114	3	c3	c3	PROPN
american_scientific_journal-766	114	4	is	be	AUX
american_scientific_journal-766	114	5	a	a	DET
american_scientific_journal-766	114	6	phase	phase	NOUN
american_scientific_journal-766	114	7	ii	ii	NOUN
american_scientific_journal-766	114	8	trial	trial	NOUN
american_scientific_journal-766	114	9	for	for	ADP
american_scientific_journal-766	114	10	160	160	NUM
american_scientific_journal-766	114	11	naïve	naïve	ADJ
american_scientific_journal-766	114	12	g1	g1	NOUN
american_scientific_journal-766	114	13	infected	infect	VERB
american_scientific_journal-766	114	14	patients	patient	NOUN
american_scientific_journal-766	114	15	.	.	PUNCT
american_scientific_journal-766	115	1	faldaprevir	faldaprevir	PROPN
american_scientific_journal-766	115	2	was	be	AUX
american_scientific_journal-766	115	3	taken	take	VERB
american_scientific_journal-766	115	4	for	for	ADP
american_scientific_journal-766	115	5	12–24	12–24	NUM
american_scientific_journal-766	115	6	weeks	week	NOUN
american_scientific_journal-766	115	7	with	with	ADP
american_scientific_journal-766	115	8	24–48	24–48	NUM
american_scientific_journal-766	115	9	weeks	week	NOUN
american_scientific_journal-766	115	10	of	of	ADP
american_scientific_journal-766	115	11	pegylated	pegylated	ADJ
american_scientific_journal-766	115	12	interferon	interferon	NOUN
american_scientific_journal-766	115	13	and	and	CCONJ
american_scientific_journal-766	115	14	ribavirin	ribavirin	NOUN
american_scientific_journal-766	115	15	.	.	PUNCT
american_scientific_journal-766	116	1	svr	svr	PROPN
american_scientific_journal-766	116	2	rates	rate	NOUN
american_scientific_journal-766	116	3	were	be	AUX
american_scientific_journal-766	116	4	67	67	NUM
american_scientific_journal-766	116	5	%	%	NOUN
american_scientific_journal-766	116	6	(	(	PUNCT
american_scientific_journal-766	116	7	if	if	SCONJ
american_scientific_journal-766	116	8	12	12	NUM
american_scientific_journal-766	116	9	weeks	week	NOUN
american_scientific_journal-766	116	10	)	)	PUNCT
american_scientific_journal-766	116	11	and	and	CCONJ
american_scientific_journal-766	116	12	74	74	NUM
american_scientific_journal-766	116	13	%	%	NOUN
american_scientific_journal-766	116	14	(	(	PUNCT
american_scientific_journal-766	116	15	if	if	SCONJ
american_scientific_journal-766	116	16	24	24	NUM
american_scientific_journal-766	116	17	weeks	week	NOUN
american_scientific_journal-766	116	18	)	)	PUNCT
american_scientific_journal-766	117	1	[	[	X
american_scientific_journal-766	117	2	41	41	NUM
american_scientific_journal-766	117	3	]	]	PUNCT
american_scientific_journal-766	117	4	.	.	PUNCT
american_scientific_journal-766	118	1	2.2.2	2.2.2	X
american_scientific_journal-766	118	2	.	.	PUNCT
american_scientific_journal-766	119	1	ns5a	ns5a	ADJ
american_scientific_journal-766	119	2	inhibitors	inhibitor	NOUN
american_scientific_journal-766	119	3	;	;	PUNCT
american_scientific_journal-766	119	4	the	the	DET
american_scientific_journal-766	119	5	ns5a	ns5a	ADJ
american_scientific_journal-766	119	6	protein	protein	NOUN
american_scientific_journal-766	119	7	is	be	AUX
american_scientific_journal-766	119	8	a	a	DET
american_scientific_journal-766	119	9	regulator	regulator	NOUN
american_scientific_journal-766	119	10	of	of	ADP
american_scientific_journal-766	119	11	replication	replication	NOUN
american_scientific_journal-766	119	12	.	.	PUNCT
american_scientific_journal-766	120	1	ns5a	ns5a	ADJ
american_scientific_journal-766	120	2	inhibitors	inhibitor	NOUN
american_scientific_journal-766	120	3	have	have	VERB
american_scientific_journal-766	120	4	high	high	ADJ
american_scientific_journal-766	120	5	antiviral	antiviral	ADJ
american_scientific_journal-766	120	6	activity	activity	NOUN
american_scientific_journal-766	120	7	against	against	ADP
american_scientific_journal-766	120	8	different	different	ADJ
american_scientific_journal-766	120	9	genotypes	genotype	NOUN
american_scientific_journal-766	120	10	,	,	PUNCT
american_scientific_journal-766	120	11	but	but	CCONJ
american_scientific_journal-766	120	12	a	a	DET
american_scientific_journal-766	120	13	low	low	ADJ
american_scientific_journal-766	120	14	genetic	genetic	ADJ
american_scientific_journal-766	120	15	barrier	barrier	NOUN
american_scientific_journal-766	120	16	to	to	ADP
american_scientific_journal-766	120	17	resistance	resistance	NOUN
american_scientific_journal-766	120	18	.	.	PUNCT
american_scientific_journal-766	121	1	resistance	resistance	NOUN
american_scientific_journal-766	121	2	variants	variant	NOUN
american_scientific_journal-766	121	3	to	to	ADP
american_scientific_journal-766	121	4	ns5a	ns5a	VERB
american_scientific_journal-766	121	5	inhibitors	inhibitor	NOUN
american_scientific_journal-766	121	6	are	be	AUX
american_scientific_journal-766	121	7	not	not	PART
american_scientific_journal-766	121	8	associated	associate	VERB
american_scientific_journal-766	121	9	with	with	ADP
american_scientific_journal-766	121	10	impaired	impaired	ADJ
american_scientific_journal-766	121	11	viral	viral	ADJ
american_scientific_journal-766	121	12	replication	replication	NOUN
american_scientific_journal-766	121	13	fitness	fitness	NOUN
american_scientific_journal-766	121	14	and	and	CCONJ
american_scientific_journal-766	121	15	they	they	PRON
american_scientific_journal-766	121	16	do	do	AUX
american_scientific_journal-766	121	17	not	not	PART
american_scientific_journal-766	121	18	disappear	disappear	VERB
american_scientific_journal-766	121	19	after	after	ADP
american_scientific_journal-766	121	20	the	the	DET
american_scientific_journal-766	121	21	end	end	NOUN
american_scientific_journal-766	121	22	of	of	ADP
american_scientific_journal-766	121	23	treatment	treatment	NOUN
american_scientific_journal-766	121	24	.	.	PUNCT
american_scientific_journal-766	122	1	persistence	persistence	NOUN
american_scientific_journal-766	122	2	of	of	ADP
american_scientific_journal-766	122	3	ns5a	ns5a	PROPN
american_scientific_journal-766	122	4	resistance	resistance	NOUN
american_scientific_journal-766	122	5	mutations	mutation	NOUN
american_scientific_journal-766	122	6	was	be	AUX
american_scientific_journal-766	122	7	detected	detect	VERB
american_scientific_journal-766	122	8	up	up	ADP
american_scientific_journal-766	122	9	to	to	ADP
american_scientific_journal-766	122	10	one	one	NUM
american_scientific_journal-766	122	11	year	year	NOUN
american_scientific_journal-766	122	12	after	after	ADP
american_scientific_journal-766	122	13	stopping	stop	VERB
american_scientific_journal-766	122	14	treatment	treatment	NOUN
american_scientific_journal-766	122	15	[	[	X
american_scientific_journal-766	122	16	43	43	NUM
american_scientific_journal-766	122	17	]	]	PUNCT
american_scientific_journal-766	122	18	.	.	PUNCT
american_scientific_journal-766	123	1	other	other	ADJ
american_scientific_journal-766	123	2	ns5a	ns5a	ADJ
american_scientific_journal-766	123	3	inhibitors	inhibitor	NOUN
american_scientific_journal-766	123	4	such	such	ADJ
american_scientific_journal-766	123	5	as	as	ADP
american_scientific_journal-766	123	6	ach-3102	ach-3102	NOUN
american_scientific_journal-766	123	7	samatasvir	samatasvir	PROPN
american_scientific_journal-766	123	8	and	and	CCONJ
american_scientific_journal-766	123	9	gs-5816	gs-5816	PROPN
american_scientific_journal-766	123	10	bms-824393	bms-824393	PROPN
american_scientific_journal-766	123	11	,	,	PUNCT
american_scientific_journal-766	123	12	ppi-461	ppi-461	NOUN
american_scientific_journal-766	123	13	,	,	PUNCT
american_scientific_journal-766	123	14	ledipasvir	ledipasvir	X
american_scientific_journal-766	123	15	(	(	PUNCT
american_scientific_journal-766	123	16	gs-5885	gs-5885	PROPN
american_scientific_journal-766	123	17	)	)	PUNCT
american_scientific_journal-766	123	18	and	and	CCONJ
american_scientific_journal-766	123	19	abt-267	abt-267	NOUN
american_scientific_journal-766	123	20	are	be	AUX
american_scientific_journal-766	123	21	still	still	ADV
american_scientific_journal-766	123	22	under	under	ADP
american_scientific_journal-766	123	23	clinical	clinical	ADJ
american_scientific_journal-766	123	24	development	development	NOUN
american_scientific_journal-766	123	25	[	[	X
american_scientific_journal-766	123	26	44	44	NUM
american_scientific_journal-766	123	27	]	]	PUNCT
american_scientific_journal-766	123	28	,	,	PUNCT
american_scientific_journal-766	123	29	[	[	X
american_scientific_journal-766	123	30	45	45	NUM
american_scientific_journal-766	123	31	]	]	PUNCT
american_scientific_journal-766	123	32	,	,	PUNCT
american_scientific_journal-766	123	33	[	[	X
american_scientific_journal-766	123	34	46	46	NUM
american_scientific_journal-766	123	35	]	]	X
american_scientific_journal-766	123	36	(	(	PUNCT
american_scientific_journal-766	123	37	table	table	NOUN
american_scientific_journal-766	123	38	1	1	NUM
american_scientific_journal-766	123	39	)	)	PUNCT
american_scientific_journal-766	123	40	.	.	PUNCT
american_scientific_journal-766	124	1	2.2.2.1	2.2.2.1	X
american_scientific_journal-766	124	2	.	.	PUNCT
american_scientific_journal-766	124	3	daclatasvir	daclatasvir	PROPN
american_scientific_journal-766	124	4	daclatasvir	daclatasvir	PROPN
american_scientific_journal-766	124	5	(	(	PUNCT
american_scientific_journal-766	124	6	bms-790052	bms-790052	NOUN
american_scientific_journal-766	124	7	)	)	PUNCT
american_scientific_journal-766	124	8	,	,	PUNCT
american_scientific_journal-766	124	9	produced	produce	VERB
american_scientific_journal-766	124	10	by	by	ADP
american_scientific_journal-766	124	11	bristol	bristol	PROPN
american_scientific_journal-766	124	12	-	-	PUNCT
american_scientific_journal-766	124	13	myers	myers	PROPN
american_scientific_journal-766	124	14	squibb	squibb	PROPN
american_scientific_journal-766	124	15	,	,	PUNCT
american_scientific_journal-766	124	16	is	be	AUX
american_scientific_journal-766	124	17	the	the	DET
american_scientific_journal-766	124	18	first	first	ADJ
american_scientific_journal-766	124	19	-	-	PUNCT
american_scientific_journal-766	124	20	in	in	ADP
american_scientific_journal-766	124	21	-	-	PUNCT
american_scientific_journal-766	124	22	class	class	NOUN
american_scientific_journal-766	124	23	ns5a	ns5a	ADJ
american_scientific_journal-766	124	24	inhibitor	inhibitor	NOUN
american_scientific_journal-766	124	25	that	that	PRON
american_scientific_journal-766	124	26	demonstrated	demonstrate	VERB
american_scientific_journal-766	124	27	a	a	DET
american_scientific_journal-766	124	28	satisfactory	satisfactory	ADJ
american_scientific_journal-766	124	29	multiphase	multiphase	NOUN
american_scientific_journal-766	124	30	rapid	rapid	ADJ
american_scientific_journal-766	124	31	hcv	hcv	PROPN
american_scientific_journal-766	124	32	rna	rna	NOUN
american_scientific_journal-766	124	33	decline	decline	NOUN
american_scientific_journal-766	124	34	without	without	ADP
american_scientific_journal-766	124	35	significant	significant	ADJ
american_scientific_journal-766	124	36	adverse	adverse	ADJ
american_scientific_journal-766	124	37	events	event	NOUN
american_scientific_journal-766	124	38	.	.	PUNCT
american_scientific_journal-766	125	1	it	it	PRON
american_scientific_journal-766	125	2	is	be	AUX
american_scientific_journal-766	125	3	highly	highly	ADV
american_scientific_journal-766	125	4	effective	effective	ADJ
american_scientific_journal-766	125	5	against	against	ADP
american_scientific_journal-766	125	6	genotypes	genotype	NOUN
american_scientific_journal-766	125	7	1–4	1–4	PROPN
american_scientific_journal-766	126	1	[	[	X
american_scientific_journal-766	126	2	47	47	NUM
american_scientific_journal-766	126	3	]	]	PUNCT
american_scientific_journal-766	126	4	.	.	PUNCT
american_scientific_journal-766	127	1	several	several	ADJ
american_scientific_journal-766	127	2	clinical	clinical	ADJ
american_scientific_journal-766	127	3	trials	trial	NOUN
american_scientific_journal-766	127	4	assessed	assess	VERB
american_scientific_journal-766	127	5	the	the	DET
american_scientific_journal-766	127	6	efficacy	efficacy	NOUN
american_scientific_journal-766	127	7	of	of	ADP
american_scientific_journal-766	127	8	daclatasvir	daclatasvir	PROPN
american_scientific_journal-766	127	9	with	with	ADP
american_scientific_journal-766	127	10	different	different	ADJ
american_scientific_journal-766	127	11	compounds	compound	NOUN
american_scientific_journal-766	127	12	.	.	PUNCT
american_scientific_journal-766	128	1	using	use	VERB
american_scientific_journal-766	128	2	daclatasvir	daclatasvir	NOUN
american_scientific_journal-766	128	3	with	with	ADP
american_scientific_journal-766	128	4	interferon	interferon	NOUN
american_scientific_journal-766	128	5	and	and	CCONJ
american_scientific_journal-766	128	6	ribavirin	ribavirin	NOUN
american_scientific_journal-766	128	7	,	,	PUNCT
american_scientific_journal-766	128	8	suzuki	suzuki	PROPN
american_scientific_journal-766	128	9	et	et	PROPN
american_scientific_journal-766	128	10	al	al	PROPN
american_scientific_journal-766	128	11	.	.	PROPN
american_scientific_journal-766	128	12	managed	manage	VERB
american_scientific_journal-766	128	13	hcv	hcv	NOUN
american_scientific_journal-766	128	14	patients	patient	NOUN
american_scientific_journal-766	128	15	who	who	PRON
american_scientific_journal-766	128	16	were	be	AUX
american_scientific_journal-766	128	17	treatment	treatment	NOUN
american_scientific_journal-766	128	18	naïve	naïve	ADJ
american_scientific_journal-766	128	19	,	,	PUNCT
american_scientific_journal-766	128	20	prior	prior	ADJ
american_scientific_journal-766	128	21	null	null	ADJ
american_scientific_journal-766	128	22	or	or	CCONJ
american_scientific_journal-766	128	23	partial	partial	ADJ
american_scientific_journal-766	128	24	responders	responder	NOUN
american_scientific_journal-766	128	25	.	.	PUNCT
american_scientific_journal-766	129	1	two	two	NUM
american_scientific_journal-766	129	2	different	different	ADJ
american_scientific_journal-766	129	3	concentrations	concentration	NOUN
american_scientific_journal-766	129	4	of	of	ADP
american_scientific_journal-766	129	5	daclatasvir	daclatasvir	NOUN
american_scientific_journal-766	129	6	were	be	AUX
american_scientific_journal-766	129	7	used	use	VERB
american_scientific_journal-766	129	8	(	(	PUNCT
american_scientific_journal-766	129	9	10	10	NUM
american_scientific_journal-766	129	10	and	and	CCONJ
american_scientific_journal-766	129	11	60	60	NUM
american_scientific_journal-766	129	12	mg	mg	NUM
american_scientific_journal-766	129	13	)	)	PUNCT
american_scientific_journal-766	129	14	versus	versus	ADP
american_scientific_journal-766	129	15	a	a	DET
american_scientific_journal-766	129	16	placebo	placebo	NOUN
american_scientific_journal-766	129	17	group	group	NOUN
american_scientific_journal-766	129	18	.	.	PUNCT
american_scientific_journal-766	130	1	svr24	svr24	PROPN
american_scientific_journal-766	130	2	reached	reach	VERB
american_scientific_journal-766	130	3	66.7–90	66.7–90	NUM
american_scientific_journal-766	130	4	%	%	NOUN
american_scientific_journal-766	130	5	in	in	ADP
american_scientific_journal-766	130	6	naïve	naïve	ADJ
american_scientific_journal-766	130	7	group	group	NOUN
american_scientific_journal-766	130	8	versus	versus	ADP
american_scientific_journal-766	130	9	62.5	62.5	NUM
american_scientific_journal-766	130	10	%	%	NOUN
american_scientific_journal-766	130	11	in	in	ADP
american_scientific_journal-766	130	12	placebo	placebo	NOUN
american_scientific_journal-766	130	13	group	group	NOUN
american_scientific_journal-766	130	14	and	and	CCONJ
american_scientific_journal-766	130	15	much	much	ADV
american_scientific_journal-766	130	16	less	less	ADJ
american_scientific_journal-766	130	17	satisfactory	satisfactory	ADJ
american_scientific_journal-766	130	18	results	result	NOUN
american_scientific_journal-766	130	19	in	in	ADP
american_scientific_journal-766	130	20	prior	prior	ADJ
american_scientific_journal-766	130	21	null	null	ADJ
american_scientific_journal-766	130	22	responders	responder	NOUN
american_scientific_journal-766	130	23	(	(	PUNCT
american_scientific_journal-766	130	24	22–33.3	22–33.3	NUM
american_scientific_journal-766	130	25	%	%	NOUN
american_scientific_journal-766	130	26	)	)	PUNCT
american_scientific_journal-766	131	1	[	[	X
american_scientific_journal-766	131	2	48	48	NUM
american_scientific_journal-766	131	3	]	]	PUNCT
american_scientific_journal-766	131	4	.	.	PUNCT
american_scientific_journal-766	132	1	naïve	naïve	ADJ
american_scientific_journal-766	132	2	group	group	NOUN
american_scientific_journal-766	132	3	had	have	AUX
american_scientific_journal-766	132	4	svr24	svr24	PROPN
american_scientific_journal-766	132	5	89–100	89–100	NUM
american_scientific_journal-766	132	6	%	%	NOUN
american_scientific_journal-766	132	7	while	while	SCONJ
american_scientific_journal-766	132	8	null	null	ADJ
american_scientific_journal-766	132	9	responders	responder	NOUN
american_scientific_journal-766	132	10	group	group	NOUN
american_scientific_journal-766	132	11	50–78	50–78	NUM
american_scientific_journal-766	132	12	%	%	NOUN
american_scientific_journal-766	132	13	[	[	X
american_scientific_journal-766	132	14	49	49	NUM
american_scientific_journal-766	132	15	]	]	PUNCT
american_scientific_journal-766	132	16	.	.	PUNCT
american_scientific_journal-766	133	1	2.2.2.2	2.2.2.2	NUM
american_scientific_journal-766	133	2	.	.	PROPN
american_scientific_journal-766	133	3	ledipasvir	ledipasvir	PROPN
american_scientific_journal-766	133	4	ledipasvir	ledipasvir	PROPN
american_scientific_journal-766	133	5	is	be	AUX
american_scientific_journal-766	133	6	another	another	DET
american_scientific_journal-766	133	7	ns5a	ns5a	ADJ
american_scientific_journal-766	133	8	inhibitor	inhibitor	NOUN
american_scientific_journal-766	133	9	that	that	PRON
american_scientific_journal-766	133	10	showed	show	VERB
american_scientific_journal-766	133	11	promising	promising	ADJ
american_scientific_journal-766	133	12	results	result	NOUN
american_scientific_journal-766	133	13	in	in	ADP
american_scientific_journal-766	133	14	different	different	ADJ
american_scientific_journal-766	133	15	trials	trial	NOUN
american_scientific_journal-766	133	16	that	that	PRON
american_scientific_journal-766	133	17	evaluated	evaluate	VERB
american_scientific_journal-766	133	18	its	its	PRON
american_scientific_journal-766	133	19	combination	combination	NOUN
american_scientific_journal-766	133	20	to	to	ADP
american_scientific_journal-766	133	21	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	133	22	.	.	PUNCT
american_scientific_journal-766	134	1	it	it	PRON
american_scientific_journal-766	134	2	provided	provide	VERB
american_scientific_journal-766	134	3	high	high	ADJ
american_scientific_journal-766	134	4	potency	potency	NOUN
american_scientific_journal-766	134	5	against	against	ADP
american_scientific_journal-766	134	6	hcv	hcv	NOUN
american_scientific_journal-766	134	7	genotypes	genotype	NOUN
american_scientific_journal-766	134	8	1a	1a	NOUN
american_scientific_journal-766	134	9	,	,	PUNCT
american_scientific_journal-766	134	10	1b	1b	NUM
american_scientific_journal-766	134	11	,	,	PUNCT
american_scientific_journal-766	134	12	4a	4a	NOUN
american_scientific_journal-766	134	13	and	and	CCONJ
american_scientific_journal-766	134	14	6a	6a	NOUN
american_scientific_journal-766	134	15	while	while	SCONJ
american_scientific_journal-766	134	16	it	it	PRON
american_scientific_journal-766	134	17	was	be	AUX
american_scientific_journal-766	134	18	less	less	ADV
american_scientific_journal-766	134	19	efficacious	efficacious	ADJ
american_scientific_journal-766	134	20	against	against	ADP
american_scientific_journal-766	134	21	genotypes	genotype	NOUN
american_scientific_journal-766	134	22	2a	2a	NUM
american_scientific_journal-766	134	23	and	and	CCONJ
american_scientific_journal-766	134	24	3a	3a	NUM
american_scientific_journal-766	134	25	[	[	X
american_scientific_journal-766	134	26	50	50	NUM
american_scientific_journal-766	134	27	]	]	PUNCT
american_scientific_journal-766	134	28	.	.	PUNCT
american_scientific_journal-766	135	1	it	it	PRON
american_scientific_journal-766	135	2	can	can	AUX
american_scientific_journal-766	135	3	not	not	PART
american_scientific_journal-766	135	4	be	be	AUX
american_scientific_journal-766	135	5	used	use	VERB
american_scientific_journal-766	135	6	alone	alone	ADJ
american_scientific_journal-766	135	7	due	due	ADP
american_scientific_journal-766	135	8	to	to	ADP
american_scientific_journal-766	135	9	quick	quick	ADJ
american_scientific_journal-766	135	10	development	development	NOUN
american_scientific_journal-766	135	11	of	of	ADP
american_scientific_journal-766	135	12	resistance	resistance	NOUN
american_scientific_journal-766	135	13	[	[	X
american_scientific_journal-766	135	14	51	51	NUM
american_scientific_journal-766	135	15	]	]	PUNCT
american_scientific_journal-766	135	16	.	.	PUNCT
american_scientific_journal-766	136	1	2.2.2.3	2.2.2.3	X
american_scientific_journal-766	136	2	.	.	PUNCT
american_scientific_journal-766	136	3	cyclophilin	cyclophilin	PROPN
american_scientific_journal-766	136	4	a	a	DET
american_scientific_journal-766	136	5	inhibitors	inhibitor	NOUN
american_scientific_journal-766	136	6	cyclophilins	cyclophilin	NOUN
american_scientific_journal-766	136	7	are	be	AUX
american_scientific_journal-766	136	8	host	host	NOUN
american_scientific_journal-766	136	9	proteins	protein	NOUN
american_scientific_journal-766	136	10	involved	involve	VERB
american_scientific_journal-766	136	11	in	in	ADP
american_scientific_journal-766	136	12	protein	protein	NOUN
american_scientific_journal-766	136	13	folding	folding	NOUN
american_scientific_journal-766	136	14	.	.	PUNCT
american_scientific_journal-766	137	1	they	they	PRON
american_scientific_journal-766	137	2	play	play	VERB
american_scientific_journal-766	137	3	an	an	DET
american_scientific_journal-766	137	4	important	important	ADJ
american_scientific_journal-766	137	5	role	role	NOUN
american_scientific_journal-766	137	6	in	in	ADP
american_scientific_journal-766	137	7	the	the	DET
american_scientific_journal-766	137	8	hcv	hcv	NOUN
american_scientific_journal-766	137	9	lifecycle	lifecycle	NOUN
american_scientific_journal-766	137	10	as	as	ADP
american_scientific_journal-766	137	11	7	7	NUM
american_scientific_journal-766	137	12	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0205	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0205	NOUN
american_scientific_journal-766	137	13	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0215	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0215	ADJ
american_scientific_journal-766	137	14	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0220	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0220	NOUN
american_scientific_journal-766	137	15	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0325	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0325	X
american_scientific_journal-766	137	16	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0330	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0330	PROPN
american_scientific_journal-766	137	17	american	american	PROPN
american_scientific_journal-766	137	18	scientific	scientific	ADJ
american_scientific_journal-766	137	19	research	research	PROPN
american_scientific_journal-766	137	20	journal	journal	NOUN
american_scientific_journal-766	137	21	for	for	ADP
american_scientific_journal-766	137	22	engineering	engineering	NOUN
american_scientific_journal-766	137	23	,	,	PUNCT
american_scientific_journal-766	137	24	technology	technology	NOUN
american_scientific_journal-766	137	25	,	,	PUNCT
american_scientific_journal-766	137	26	and	and	CCONJ
american_scientific_journal-766	137	27	sciences	science	NOUN
american_scientific_journal-766	137	28	(	(	PUNCT
american_scientific_journal-766	137	29	asrjets	asrjet	NOUN
american_scientific_journal-766	137	30	)	)	PUNCT
american_scientific_journal-766	137	31	(	(	PUNCT
american_scientific_journal-766	137	32	2015	2015	NUM
american_scientific_journal-766	137	33	)	)	PUNCT
american_scientific_journal-766	137	34	volume	volume	NOUN
american_scientific_journal-766	137	35	13	13	NUM
american_scientific_journal-766	137	36	,	,	PUNCT
american_scientific_journal-766	137	37	no	no	DET
american_scientific_journal-766	137	38	1	1	NUM
american_scientific_journal-766	137	39	,	,	PUNCT
american_scientific_journal-766	137	40	pp	pp	ADV
american_scientific_journal-766	137	41	1	1	NUM
american_scientific_journal-766	137	42	-	-	SYM
american_scientific_journal-766	137	43	23	23	NUM
american_scientific_journal-766	137	44	regulators	regulator	NOUN
american_scientific_journal-766	137	45	of	of	ADP
american_scientific_journal-766	137	46	replication	replication	NOUN
american_scientific_journal-766	137	47	.	.	PUNCT
american_scientific_journal-766	138	1	the	the	DET
american_scientific_journal-766	138	2	cyclophilin	cyclophilin	PROPN
american_scientific_journal-766	138	3	inhibitor	inhibitor	NOUN
american_scientific_journal-766	138	4	alisporivir	alisporivir	PROPN
american_scientific_journal-766	138	5	(	(	PUNCT
american_scientific_journal-766	138	6	deb-025	deb-025	NOUN
american_scientific_journal-766	138	7	)	)	PUNCT
american_scientific_journal-766	138	8	is	be	AUX
american_scientific_journal-766	138	9	a	a	DET
american_scientific_journal-766	138	10	cyclosporine	cyclosporine	ADJ
american_scientific_journal-766	138	11	analog	analog	NOUN
american_scientific_journal-766	138	12	without	without	ADP
american_scientific_journal-766	138	13	its	its	PRON
american_scientific_journal-766	138	14	immunosuppressive	immunosuppressive	ADJ
american_scientific_journal-766	138	15	properties	property	NOUN
american_scientific_journal-766	138	16	that	that	PRON
american_scientific_journal-766	138	17	has	have	AUX
american_scientific_journal-766	138	18	shown	show	VERB
american_scientific_journal-766	138	19	pan	pan	ADJ
american_scientific_journal-766	138	20	-	-	ADJ
american_scientific_journal-766	138	21	genotypic	genotypic	ADJ
american_scientific_journal-766	138	22	antiviral	antiviral	ADJ
american_scientific_journal-766	138	23	activity	activity	NOUN
american_scientific_journal-766	138	24	and	and	CCONJ
american_scientific_journal-766	138	25	has	have	AUX
american_scientific_journal-766	138	26	been	be	AUX
american_scientific_journal-766	138	27	used	use	VERB
american_scientific_journal-766	138	28	both	both	CCONJ
american_scientific_journal-766	138	29	alone	alone	ADJ
american_scientific_journal-766	138	30	and	and	CCONJ
american_scientific_journal-766	138	31	in	in	ADP
american_scientific_journal-766	138	32	combination	combination	NOUN
american_scientific_journal-766	138	33	with	with	ADP
american_scientific_journal-766	138	34	peg	peg	NOUN
american_scientific_journal-766	138	35	-	-	PUNCT
american_scientific_journal-766	138	36	ifn	ifn	PROPN
american_scientific_journal-766	138	37	and	and	CCONJ
american_scientific_journal-766	138	38	rbv	rbv	VERB
american_scientific_journal-766	138	39	with	with	ADP
american_scientific_journal-766	138	40	promising	promising	ADJ
american_scientific_journal-766	138	41	results	result	NOUN
american_scientific_journal-766	138	42	[	[	X
american_scientific_journal-766	138	43	52	52	NUM
american_scientific_journal-766	138	44	]	]	PUNCT
american_scientific_journal-766	138	45	.	.	PUNCT
american_scientific_journal-766	139	1	2.2.3	2.2.3	X
american_scientific_journal-766	139	2	.	.	PUNCT
american_scientific_journal-766	139	3	ns5b	ns5b	ADJ
american_scientific_journal-766	139	4	polymerase	polymerase	NOUN
american_scientific_journal-766	139	5	inhibitors	inhibitor	NOUN
american_scientific_journal-766	139	6	there	there	PRON
american_scientific_journal-766	139	7	are	be	VERB
american_scientific_journal-766	139	8	two	two	NUM
american_scientific_journal-766	139	9	categories	category	NOUN
american_scientific_journal-766	139	10	of	of	ADP
american_scientific_journal-766	139	11	ns5b	ns5b	ADJ
american_scientific_journal-766	139	12	polymerase	polymerase	NOUN
american_scientific_journal-766	139	13	inhibitors	inhibitor	NOUN
american_scientific_journal-766	139	14	:	:	PUNCT
american_scientific_journal-766	139	15	nucleos(t)ide	nucleos(t)ide	ADV
american_scientific_journal-766	139	16	(	(	PUNCT
american_scientific_journal-766	139	17	nis	nis	NOUN
american_scientific_journal-766	139	18	)	)	PUNCT
american_scientific_journal-766	139	19	and	and	CCONJ
american_scientific_journal-766	139	20	non	non	ADJ
american_scientific_journal-766	139	21	-	-	ADJ
american_scientific_journal-766	139	22	nucleoside	nucleoside	ADJ
american_scientific_journal-766	139	23	inhibitors	inhibitor	NOUN
american_scientific_journal-766	139	24	(	(	PUNCT
american_scientific_journal-766	139	25	nnis	nnis	PROPN
american_scientific_journal-766	139	26	)	)	PUNCT
american_scientific_journal-766	139	27	(	(	PUNCT
american_scientific_journal-766	139	28	table	table	NOUN
american_scientific_journal-766	139	29	1	1	NUM
american_scientific_journal-766	139	30	)	)	PUNCT
american_scientific_journal-766	139	31	.	.	PUNCT
american_scientific_journal-766	140	1	nis	nis	PROPN
american_scientific_journal-766	140	2	mimic	mimic	VERB
american_scientific_journal-766	140	3	the	the	DET
american_scientific_journal-766	140	4	naturally	naturally	ADV
american_scientific_journal-766	140	5	occurring	occur	VERB
american_scientific_journal-766	140	6	nucleos(t)ides	nucleos(t)ide	NOUN
american_scientific_journal-766	140	7	and	and	CCONJ
american_scientific_journal-766	140	8	thus	thus	ADV
american_scientific_journal-766	140	9	are	be	AUX
american_scientific_journal-766	140	10	incorporated	incorporate	VERB
american_scientific_journal-766	140	11	into	into	ADP
american_scientific_journal-766	140	12	the	the	DET
american_scientific_journal-766	140	13	nascent	nascent	ADJ
american_scientific_journal-766	140	14	rna	rna	NOUN
american_scientific_journal-766	140	15	chain	chain	NOUN
american_scientific_journal-766	140	16	causing	cause	VERB
american_scientific_journal-766	140	17	premature	premature	ADJ
american_scientific_journal-766	140	18	chain	chain	NOUN
american_scientific_journal-766	140	19	termination	termination	NOUN
american_scientific_journal-766	141	1	[	[	X
american_scientific_journal-766	141	2	53	53	NUM
american_scientific_journal-766	141	3	]	]	PUNCT
american_scientific_journal-766	141	4	.	.	PUNCT
american_scientific_journal-766	142	1	nis	nis	PROPN
american_scientific_journal-766	142	2	are	be	AUX
american_scientific_journal-766	142	3	considered	consider	VERB
american_scientific_journal-766	142	4	to	to	PART
american_scientific_journal-766	142	5	have	have	VERB
american_scientific_journal-766	142	6	a	a	DET
american_scientific_journal-766	142	7	high	high	ADJ
american_scientific_journal-766	142	8	genetic	genetic	ADJ
american_scientific_journal-766	142	9	barrier	barrier	NOUN
american_scientific_journal-766	142	10	to	to	ADP
american_scientific_journal-766	142	11	resistance	resistance	NOUN
american_scientific_journal-766	142	12	,	,	PUNCT
american_scientific_journal-766	142	13	although	although	SCONJ
american_scientific_journal-766	142	14	single	single	ADJ
american_scientific_journal-766	142	15	amino	amino	NOUN
american_scientific_journal-766	142	16	acid	acid	NOUN
american_scientific_journal-766	142	17	substitutions	substitution	NOUN
american_scientific_journal-766	142	18	are	be	AUX
american_scientific_journal-766	142	19	able	able	ADJ
american_scientific_journal-766	142	20	to	to	PART
american_scientific_journal-766	142	21	confer	confer	VERB
american_scientific_journal-766	142	22	drug	drug	NOUN
american_scientific_journal-766	142	23	resistance	resistance	NOUN
american_scientific_journal-766	142	24	in	in	ADP
american_scientific_journal-766	142	25	vitro	vitro	X
american_scientific_journal-766	142	26	.	.	PUNCT
american_scientific_journal-766	143	1	nis	nis	PROPN
american_scientific_journal-766	143	2	have	have	VERB
american_scientific_journal-766	143	3	antiviral	antiviral	ADJ
american_scientific_journal-766	143	4	activity	activity	NOUN
american_scientific_journal-766	143	5	against	against	ADP
american_scientific_journal-766	143	6	all	all	DET
american_scientific_journal-766	143	7	hcv	hcv	NOUN
american_scientific_journal-766	143	8	genotypes	genotype	NOUN
american_scientific_journal-766	143	9	(	(	PUNCT
american_scientific_journal-766	143	10	pan	pan	ADJ
american_scientific_journal-766	143	11	-	-	ADJ
american_scientific_journal-766	143	12	genotype	genotype	NOUN
american_scientific_journal-766	143	13	activity	activity	NOUN
american_scientific_journal-766	143	14	)	)	PUNCT
american_scientific_journal-766	143	15	as	as	SCONJ
american_scientific_journal-766	143	16	the	the	DET
american_scientific_journal-766	143	17	active	active	ADJ
american_scientific_journal-766	143	18	site	site	NOUN
american_scientific_journal-766	143	19	of	of	ADP
american_scientific_journal-766	143	20	ns5b	ns5b	PROPN
american_scientific_journal-766	143	21	is	be	AUX
american_scientific_journal-766	143	22	well	well	ADV
american_scientific_journal-766	143	23	conserved	conserve	VERB
american_scientific_journal-766	143	24	across	across	ADP
american_scientific_journal-766	143	25	genotypes	genotype	NOUN
american_scientific_journal-766	143	26	[	[	PUNCT
american_scientific_journal-766	143	27	54].ns5a	54].ns5a	NUM
american_scientific_journal-766	143	28	inhibitors	inhibitor	NOUN
american_scientific_journal-766	143	29	showed	show	VERB
american_scientific_journal-766	143	30	promising	promising	ADJ
american_scientific_journal-766	143	31	results	result	NOUN
american_scientific_journal-766	143	32	among	among	ADP
american_scientific_journal-766	143	33	the	the	DET
american_scientific_journal-766	143	34	different	different	ADJ
american_scientific_journal-766	143	35	daa	daa	NOUN
american_scientific_journal-766	143	36	drug	drug	NOUN
american_scientific_journal-766	143	37	studies	study	NOUN
american_scientific_journal-766	143	38	due	due	ADP
american_scientific_journal-766	143	39	to	to	ADP
american_scientific_journal-766	143	40	their	their	PRON
american_scientific_journal-766	143	41	multigenotypic	multigenotypic	ADJ
american_scientific_journal-766	143	42	efficacy	efficacy	NOUN
american_scientific_journal-766	143	43	,	,	PUNCT
american_scientific_journal-766	143	44	high	high	ADJ
american_scientific_journal-766	143	45	potency	potency	NOUN
american_scientific_journal-766	143	46	but	but	CCONJ
american_scientific_journal-766	143	47	low	low	ADJ
american_scientific_journal-766	143	48	to	to	ADP
american_scientific_journal-766	143	49	intermediate	intermediate	ADJ
american_scientific_journal-766	143	50	barrier	barrier	NOUN
american_scientific_journal-766	143	51	to	to	ADP
american_scientific_journal-766	143	52	resistance	resistance	NOUN
american_scientific_journal-766	143	53	.	.	PUNCT
american_scientific_journal-766	144	1	several	several	ADJ
american_scientific_journal-766	144	2	nonnucleoside	nonnucleoside	ADJ
american_scientific_journal-766	144	3	inhibitors	inhibitor	NOUN
american_scientific_journal-766	144	4	(	(	PUNCT
american_scientific_journal-766	144	5	nnis	nnis	PROPN
american_scientific_journal-766	144	6	)	)	PUNCT
american_scientific_journal-766	144	7	of	of	ADP
american_scientific_journal-766	144	8	the	the	DET
american_scientific_journal-766	144	9	hcv	hcv	NOUN
american_scientific_journal-766	144	10	polymerase	polymerase	NOUN
american_scientific_journal-766	144	11	can	can	AUX
american_scientific_journal-766	144	12	prevent	prevent	VERB
american_scientific_journal-766	144	13	either	either	CCONJ
american_scientific_journal-766	144	14	de	de	PROPN
american_scientific_journal-766	144	15	novo	novo	NOUN
american_scientific_journal-766	144	16	initiated	initiate	VERB
american_scientific_journal-766	144	17	rna	rna	NOUN
american_scientific_journal-766	144	18	synthesis	synthesis	NOUN
american_scientific_journal-766	144	19	,	,	PUNCT
american_scientific_journal-766	144	20	primer	primer	NOUN
american_scientific_journal-766	144	21	-	-	PUNCT
american_scientific_journal-766	144	22	extended	extend	VERB
american_scientific_journal-766	144	23	rna	rna	NOUN
american_scientific_journal-766	144	24	synthesis	synthesis	NOUN
american_scientific_journal-766	144	25	,	,	PUNCT
american_scientific_journal-766	144	26	or	or	CCONJ
american_scientific_journal-766	144	27	both	both	PRON
american_scientific_journal-766	144	28	.	.	PUNCT
american_scientific_journal-766	145	1	these	these	DET
american_scientific_journal-766	145	2	nnis	nnis	ADJ
american_scientific_journal-766	145	3	inhibitors	inhibitor	NOUN
american_scientific_journal-766	145	4	achieve	achieve	VERB
american_scientific_journal-766	145	5	polymerase	polymerase	NOUN
american_scientific_journal-766	145	6	inhibition	inhibition	NOUN
american_scientific_journal-766	145	7	by	by	ADP
american_scientific_journal-766	145	8	binding	bind	VERB
american_scientific_journal-766	145	9	to	to	ADP
american_scientific_journal-766	145	10	one	one	NUM
american_scientific_journal-766	145	11	of	of	ADP
american_scientific_journal-766	145	12	the	the	DET
american_scientific_journal-766	145	13	at	at	ADV
american_scientific_journal-766	145	14	least	least	ADJ
american_scientific_journal-766	145	15	four	four	NUM
american_scientific_journal-766	145	16	allosteric	allosteric	ADJ
american_scientific_journal-766	145	17	enzyme	enzyme	NOUN
american_scientific_journal-766	145	18	sites	site	NOUN
american_scientific_journal-766	145	19	[	[	X
american_scientific_journal-766	145	20	55	55	NUM
american_scientific_journal-766	145	21	]	]	PUNCT
american_scientific_journal-766	145	22	.	.	PUNCT
american_scientific_journal-766	146	1	most	most	ADJ
american_scientific_journal-766	146	2	of	of	ADP
american_scientific_journal-766	146	3	them	they	PRON
american_scientific_journal-766	146	4	have	have	VERB
american_scientific_journal-766	146	5	a	a	DET
american_scientific_journal-766	146	6	genotype	genotype	NOUN
american_scientific_journal-766	146	7	-	-	PUNCT
american_scientific_journal-766	146	8	specific	specific	ADJ
american_scientific_journal-766	146	9	activity	activity	NOUN
american_scientific_journal-766	146	10	and	and	CCONJ
american_scientific_journal-766	146	11	they	they	PRON
american_scientific_journal-766	146	12	may	may	AUX
american_scientific_journal-766	146	13	select	select	VERB
american_scientific_journal-766	146	14	rapidly	rapidly	ADV
american_scientific_journal-766	146	15	drug	drug	NOUN
american_scientific_journal-766	146	16	-	-	PUNCT
american_scientific_journal-766	146	17	resistant	resistant	ADJ
american_scientific_journal-766	146	18	variants	variant	NOUN
american_scientific_journal-766	146	19	if	if	SCONJ
american_scientific_journal-766	146	20	hcv	hcv	NOUN
american_scientific_journal-766	146	21	replication	replication	NOUN
american_scientific_journal-766	146	22	is	be	AUX
american_scientific_journal-766	146	23	not	not	PART
american_scientific_journal-766	146	24	completely	completely	ADV
american_scientific_journal-766	146	25	suppressed	suppress	VERB
american_scientific_journal-766	146	26	[	[	X
american_scientific_journal-766	146	27	56	56	NUM
american_scientific_journal-766	146	28	]	]	SYM
american_scientific_journal-766	146	29	.	.	PUNCT
american_scientific_journal-766	147	1	2.2.3.1	2.2.3.1	X
american_scientific_journal-766	147	2	.	.	PUNCT
american_scientific_journal-766	147	3	dasabuvir	dasabuvir	PROPN
american_scientific_journal-766	147	4	dasabuvir	dasabuvir	PROPN
american_scientific_journal-766	147	5	(	(	PUNCT
american_scientific_journal-766	147	6	abt-333	abt-333	ADV
american_scientific_journal-766	147	7	)	)	PUNCT
american_scientific_journal-766	147	8	is	be	AUX
american_scientific_journal-766	147	9	a	a	DET
american_scientific_journal-766	147	10	ns5b	ns5b	ADJ
american_scientific_journal-766	147	11	non	non	ADJ
american_scientific_journal-766	147	12	-	-	ADJ
american_scientific_journal-766	147	13	nucleoside	nucleoside	ADJ
american_scientific_journal-766	147	14	polymerase	polymerase	NOUN
american_scientific_journal-766	147	15	inhibitor	inhibitor	NOUN
american_scientific_journal-766	147	16	(	(	PUNCT
american_scientific_journal-766	147	17	nnpis	nnpis	ADJ
american_scientific_journal-766	147	18	)	)	PUNCT
american_scientific_journal-766	147	19	.	.	PUNCT
american_scientific_journal-766	148	1	dasabuvir	dasabuvir	NOUN
american_scientific_journal-766	148	2	containing	contain	VERB
american_scientific_journal-766	148	3	regimens	regimen	NOUN
american_scientific_journal-766	148	4	achieve	achieve	VERB
american_scientific_journal-766	148	5	high	high	ADJ
american_scientific_journal-766	148	6	rates	rate	NOUN
american_scientific_journal-766	148	7	of	of	ADP
american_scientific_journal-766	148	8	sustained	sustain	VERB
american_scientific_journal-766	148	9	virologic	virologic	ADJ
american_scientific_journal-766	148	10	response	response	NOUN
american_scientific_journal-766	148	11	in	in	ADP
american_scientific_journal-766	148	12	hcv	hcv	PROPN
american_scientific_journal-766	148	13	genotype	genotype	NOUN
american_scientific_journal-766	148	14	1a	1a	NOUN
american_scientific_journal-766	148	15	and	and	CCONJ
american_scientific_journal-766	148	16	1b	1b	NUM
american_scientific_journal-766	148	17	–	–	PUNCT
american_scientific_journal-766	148	18	infected	infect	VERB
american_scientific_journal-766	148	19	patients	patient	NOUN
american_scientific_journal-766	148	20	when	when	SCONJ
american_scientific_journal-766	148	21	combined	combine	VERB
american_scientific_journal-766	148	22	with	with	ADP
american_scientific_journal-766	148	23	other	other	ADJ
american_scientific_journal-766	148	24	daas	daas	NOUN
american_scientific_journal-766	148	25	,	,	PUNCT
american_scientific_journal-766	148	26	namely	namely	ADV
american_scientific_journal-766	148	27	paritaprevir	paritaprevir	NOUN
american_scientific_journal-766	148	28	(	(	PUNCT
american_scientific_journal-766	148	29	abt-450	abt-450	NOUN
american_scientific_journal-766	148	30	)	)	PUNCT
american_scientific_journal-766	148	31	,	,	PUNCT
american_scientific_journal-766	148	32	ritonavir	ritonavir	PROPN
american_scientific_journal-766	148	33	and	and	CCONJ
american_scientific_journal-766	148	34	ombitasvir	ombitasvir	PROPN
american_scientific_journal-766	148	35	(	(	PUNCT
american_scientific_journal-766	148	36	abt-267	abt-267	NOUN
american_scientific_journal-766	148	37	)	)	PUNCT
american_scientific_journal-766	148	38	.	.	PUNCT
american_scientific_journal-766	149	1	in	in	ADP
american_scientific_journal-766	149	2	the	the	DET
american_scientific_journal-766	149	3	populations	population	NOUN
american_scientific_journal-766	149	4	studied	study	VERB
american_scientific_journal-766	149	5	,	,	PUNCT
american_scientific_journal-766	149	6	dasabuvir	dasabuvir	PROPN
american_scientific_journal-766	149	7	seems	seem	VERB
american_scientific_journal-766	149	8	to	to	PART
american_scientific_journal-766	149	9	be	be	AUX
american_scientific_journal-766	149	10	well	well	ADV
american_scientific_journal-766	149	11	tolerated	tolerate	VERB
american_scientific_journal-766	149	12	and	and	CCONJ
american_scientific_journal-766	149	13	safe	safe	ADJ
american_scientific_journal-766	149	14	and	and	CCONJ
american_scientific_journal-766	149	15	the	the	DET
american_scientific_journal-766	149	16	major	major	ADJ
american_scientific_journal-766	149	17	limitations	limitation	NOUN
american_scientific_journal-766	149	18	of	of	ADP
american_scientific_journal-766	149	19	this	this	DET
american_scientific_journal-766	149	20	novel	novel	ADJ
american_scientific_journal-766	149	21	drug	drug	NOUN
american_scientific_journal-766	149	22	are	be	AUX
american_scientific_journal-766	149	23	its	its	PRON
american_scientific_journal-766	149	24	genotype	genotype	NOUN
american_scientific_journal-766	149	25	-	-	PUNCT
american_scientific_journal-766	149	26	restricted	restrict	VERB
american_scientific_journal-766	149	27	activity	activity	NOUN
american_scientific_journal-766	149	28	,	,	PUNCT
american_scientific_journal-766	149	29	the	the	DET
american_scientific_journal-766	149	30	necessity	necessity	NOUN
american_scientific_journal-766	149	31	to	to	PART
american_scientific_journal-766	149	32	include	include	VERB
american_scientific_journal-766	149	33	ribavirin	ribavirin	NOUN
american_scientific_journal-766	149	34	for	for	ADP
american_scientific_journal-766	149	35	hcv	hcv	NOUN
american_scientific_journal-766	149	36	genotype	genotype	NOUN
american_scientific_journal-766	149	37	1a	1a	NOUN
american_scientific_journal-766	149	38	and	and	CCONJ
american_scientific_journal-766	149	39	the	the	DET
american_scientific_journal-766	149	40	emergence	emergence	NOUN
american_scientific_journal-766	149	41	of	of	ADP
american_scientific_journal-766	149	42	resistance	resistance	NOUN
american_scientific_journal-766	149	43	if	if	SCONJ
american_scientific_journal-766	149	44	not	not	PART
american_scientific_journal-766	149	45	combined	combine	VERB
american_scientific_journal-766	149	46	with	with	ADP
american_scientific_journal-766	149	47	other	other	ADJ
american_scientific_journal-766	149	48	ddas	ddas	ADJ
american_scientific_journal-766	150	1	[	[	X
american_scientific_journal-766	150	2	57	57	NUM
american_scientific_journal-766	150	3	]	]	PUNCT
american_scientific_journal-766	150	4	.	.	PUNCT
american_scientific_journal-766	151	1	2.2.3.2	2.2.3.2	X
american_scientific_journal-766	151	2	.	.	NOUN
american_scientific_journal-766	151	3	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	151	4	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	151	5	(	(	PUNCT
american_scientific_journal-766	151	6	sovaldi	sovaldi	PROPN
american_scientific_journal-766	151	7	®	®	PROPN
american_scientific_journal-766	151	8	,	,	PUNCT
american_scientific_journal-766	151	9	gilead	gilead	NOUN
american_scientific_journal-766	151	10	sciences	science	NOUN
american_scientific_journal-766	151	11	)	)	PUNCT
american_scientific_journal-766	151	12	is	be	AUX
american_scientific_journal-766	151	13	a	a	DET
american_scientific_journal-766	151	14	new	new	ADJ
american_scientific_journal-766	151	15	drug	drug	NOUN
american_scientific_journal-766	151	16	,	,	PUNCT
american_scientific_journal-766	151	17	formerly	formerly	ADV
american_scientific_journal-766	151	18	named	name	VERB
american_scientific_journal-766	151	19	gs-7977	gs-7977	PROPN
american_scientific_journal-766	151	20	,	,	PUNCT
american_scientific_journal-766	151	21	the	the	DET
american_scientific_journal-766	151	22	first	first	ADJ
american_scientific_journal-766	151	23	ns5b	ns5b	ADJ
american_scientific_journal-766	151	24	hcv	hcv	X
american_scientific_journal-766	151	25	nucleotide	nucleotide	NOUN
american_scientific_journal-766	151	26	polymerase	polymerase	NOUN
american_scientific_journal-766	151	27	inhibitor	inhibitor	NOUN
american_scientific_journal-766	151	28	(	(	PUNCT
american_scientific_journal-766	151	29	npis	npis	PROPN
american_scientific_journal-766	151	30	)	)	PUNCT
american_scientific_journal-766	151	31	,	,	PUNCT
american_scientific_journal-766	151	32	who	who	PRON
american_scientific_journal-766	151	33	's	be	AUX
american_scientific_journal-766	151	34	us	we	PRON
american_scientific_journal-766	151	35	food	food	NOUN
american_scientific_journal-766	151	36	and	and	CCONJ
american_scientific_journal-766	151	37	drug	drug	PROPN
american_scientific_journal-766	151	38	administration	administration	PROPN
american_scientific_journal-766	151	39	(	(	PUNCT
american_scientific_journal-766	151	40	fda	fda	PROPN
american_scientific_journal-766	151	41	)	)	PUNCT
american_scientific_journal-766	151	42	and	and	CCONJ
american_scientific_journal-766	151	43	european	european	ADJ
american_scientific_journal-766	151	44	medicines	medicine	NOUN
american_scientific_journal-766	151	45	agency	agency	NOUN
american_scientific_journal-766	151	46	(	(	PUNCT
american_scientific_journal-766	151	47	ema	ema	PROPN
american_scientific_journal-766	151	48	)	)	PUNCT
american_scientific_journal-766	151	49	approvals	approval	NOUN
american_scientific_journal-766	151	50	have	have	AUX
american_scientific_journal-766	151	51	been	be	AUX
american_scientific_journal-766	151	52	granted	grant	VERB
american_scientific_journal-766	151	53	at	at	ADP
american_scientific_journal-766	151	54	the	the	DET
american_scientific_journal-766	151	55	end	end	NOUN
american_scientific_journal-766	151	56	of	of	ADP
american_scientific_journal-766	151	57	2013	2013	NUM
american_scientific_journal-766	151	58	and	and	CCONJ
american_scientific_journal-766	151	59	at	at	ADP
american_scientific_journal-766	151	60	the	the	DET
american_scientific_journal-766	151	61	beginning	beginning	NOUN
american_scientific_journal-766	151	62	of	of	ADP
american_scientific_journal-766	151	63	2014	2014	NUM
american_scientific_journal-766	151	64	,	,	PUNCT
american_scientific_journal-766	151	65	respectively	respectively	ADV
american_scientific_journal-766	151	66	[	[	X
american_scientific_journal-766	151	67	58	58	NUM
american_scientific_journal-766	151	68	]	]	PUNCT
american_scientific_journal-766	151	69	.	.	PUNCT
american_scientific_journal-766	152	1	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	152	2	with	with	ADP
american_scientific_journal-766	152	3	the	the	DET
american_scientific_journal-766	152	4	chemical	chemical	NOUN
american_scientific_journal-766	152	5	name	name	NOUN
american_scientific_journal-766	152	6	l	l	NOUN
american_scientific_journal-766	152	7	-	-	NOUN
american_scientific_journal-766	152	8	alanine	alanine	NOUN
american_scientific_journal-766	152	9	,	,	PUNCT
american_scientific_journal-766	152	10	n-[[p(s),2′r]-2′-deoxy-2′-fluoro-2′-methyl	n-[[p(s),2′r]-2′-deoxy-2′-fluoro-2′-methyl	NOUN
american_scientific_journal-766	152	11	-	-	NOUN
american_scientific_journal-766	152	12	pphenyl-5′-uridylyl]-	pphenyl-5′-uridylyl]-	ADJ
american_scientific_journal-766	152	13	,	,	PUNCT
american_scientific_journal-766	152	14	1	1	NUM
american_scientific_journal-766	152	15	-	-	PUNCT
american_scientific_journal-766	152	16	methyl	methyl	NOUN
american_scientific_journal-766	152	17	-	-	PUNCT
american_scientific_journal-766	152	18	ethyl	ethyl	NOUN
american_scientific_journal-766	152	19	ester	ester	NOUN
american_scientific_journal-766	152	20	and	and	CCONJ
american_scientific_journal-766	152	21	a	a	DET
american_scientific_journal-766	152	22	molecular	molecular	ADJ
american_scientific_journal-766	152	23	formula	formula	NOUN
american_scientific_journal-766	152	24	of	of	ADP
american_scientific_journal-766	152	25	c22h29fn3o9p	c22h29fn3o9p	PROPN
american_scientific_journal-766	152	26	.	.	PUNCT
american_scientific_journal-766	153	1	it	it	PRON
american_scientific_journal-766	153	2	is	be	AUX
american_scientific_journal-766	153	3	administered	administer	VERB
american_scientific_journal-766	153	4	at	at	ADP
american_scientific_journal-766	153	5	a	a	DET
american_scientific_journal-766	153	6	dosage	dosage	NOUN
american_scientific_journal-766	153	7	of	of	ADP
american_scientific_journal-766	153	8	400	400	NUM
american_scientific_journal-766	153	9	mg	mg	ADV
american_scientific_journal-766	153	10	once	once	ADV
american_scientific_journal-766	153	11	daily	daily	ADV
american_scientific_journal-766	153	12	,	,	PUNCT
american_scientific_journal-766	153	13	taken	take	VERB
american_scientific_journal-766	153	14	with	with	ADP
american_scientific_journal-766	153	15	or	or	CCONJ
american_scientific_journal-766	153	16	without	without	ADP
american_scientific_journal-766	153	17	food	food	NOUN
american_scientific_journal-766	153	18	,	,	PUNCT
american_scientific_journal-766	153	19	and	and	CCONJ
american_scientific_journal-766	153	20	has	have	VERB
american_scientific_journal-766	153	21	a	a	DET
american_scientific_journal-766	153	22	potent	potent	ADJ
american_scientific_journal-766	153	23	activity	activity	NOUN
american_scientific_journal-766	153	24	against	against	ADP
american_scientific_journal-766	153	25	all	all	DET
american_scientific_journal-766	153	26	hcv	hcv	NOUN
american_scientific_journal-766	153	27	genotypes	genotype	NOUN
american_scientific_journal-766	153	28	[	[	X
american_scientific_journal-766	153	29	59	59	NUM
american_scientific_journal-766	153	30	]	]	PUNCT
american_scientific_journal-766	153	31	.	.	PUNCT
american_scientific_journal-766	154	1	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	154	2	is	be	AUX
american_scientific_journal-766	154	3	used	use	VERB
american_scientific_journal-766	154	4	in	in	ADP
american_scientific_journal-766	154	5	combination	combination	NOUN
american_scientific_journal-766	154	6	with	with	ADP
american_scientific_journal-766	154	7	other	other	ADJ
american_scientific_journal-766	154	8	medicines	medicine	NOUN
american_scientific_journal-766	154	9	.	.	PUNCT
american_scientific_journal-766	155	1	several	several	ADJ
american_scientific_journal-766	155	2	varieties	variety	NOUN
american_scientific_journal-766	155	3	(	(	PUNCT
american_scientific_journal-766	155	4	genotypes	genotype	NOUN
american_scientific_journal-766	155	5	)	)	PUNCT
american_scientific_journal-766	155	6	of	of	ADP
american_scientific_journal-766	155	7	hepatitis	hepatitis	PROPN
american_scientific_journal-766	155	8	c	c	PROPN
american_scientific_journal-766	155	9	virus	virus	NOUN
american_scientific_journal-766	155	10	exist	exist	VERB
american_scientific_journal-766	155	11	,	,	PUNCT
american_scientific_journal-766	155	12	and	and	CCONJ
american_scientific_journal-766	155	13	the	the	DET
american_scientific_journal-766	155	14	duration	duration	NOUN
american_scientific_journal-766	155	15	of	of	ADP
american_scientific_journal-766	155	16	treatment	treatment	NOUN
american_scientific_journal-766	155	17	with	with	ADP
american_scientific_journal-766	155	18	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	155	19	will	will	AUX
american_scientific_journal-766	155	20	depend	depend	VERB
american_scientific_journal-766	155	21	on	on	ADP
american_scientific_journal-766	155	22	the	the	DET
american_scientific_journal-766	155	23	genotype	genotype	NOUN
american_scientific_journal-766	155	24	of	of	ADP
american_scientific_journal-766	155	25	the	the	DET
american_scientific_journal-766	155	26	virus	virus	NOUN
american_scientific_journal-766	155	27	and	and	CCONJ
american_scientific_journal-766	155	28	on	on	ADP
american_scientific_journal-766	155	29	which	which	PRON
american_scientific_journal-766	155	30	medicines	medicine	NOUN
american_scientific_journal-766	155	31	are	be	AUX
american_scientific_journal-766	155	32	used	use	VERB
american_scientific_journal-766	155	33	together	together	ADV
american_scientific_journal-766	155	34	with	with	ADP
american_scientific_journal-766	155	35	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	155	36	.	.	PUNCT
american_scientific_journal-766	156	1	metabolism	metabolism	NOUN
american_scientific_journal-766	156	2	of	of	ADP
american_scientific_journal-766	156	3	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	156	4	and	and	CCONJ
american_scientific_journal-766	156	5	the	the	DET
american_scientific_journal-766	156	6	other	other	ADJ
american_scientific_journal-766	156	7	related	related	ADJ
american_scientific_journal-766	156	8	drugs	drug	NOUN
american_scientific_journal-766	156	9	of	of	ADP
american_scientific_journal-766	156	10	the	the	DET
american_scientific_journal-766	156	11	same	same	ADJ
american_scientific_journal-766	156	12	family	family	NOUN
american_scientific_journal-766	156	13	have	have	VERB
american_scientific_journal-766	156	14	no	no	DET
american_scientific_journal-766	156	15	relation	relation	NOUN
american_scientific_journal-766	156	16	with	with	ADP
american_scientific_journal-766	156	17	the	the	DET
american_scientific_journal-766	156	18	cyp3a4	cyp3a4	NOUN
american_scientific_journal-766	156	19	pathway	pathway	NOUN
american_scientific_journal-766	157	1	[	[	X
american_scientific_journal-766	157	2	60	60	NUM
american_scientific_journal-766	157	3	]	]	PUNCT
american_scientific_journal-766	157	4	.	.	PUNCT
american_scientific_journal-766	158	1	the	the	DET
american_scientific_journal-766	158	2	price	price	NOUN
american_scientific_journal-766	158	3	of	of	ADP
american_scientific_journal-766	158	4	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	158	5	,	,	PUNCT
american_scientific_journal-766	158	6	quoted	quote	VERB
american_scientific_journal-766	158	7	in	in	ADP
american_scientific_journal-766	158	8	various	various	ADJ
american_scientific_journal-766	158	9	media	medium	NOUN
american_scientific_journal-766	158	10	sources	source	NOUN
american_scientific_journal-766	158	11	as	as	ADP
american_scientific_journal-766	158	12	$	$	SYM
american_scientific_journal-766	158	13	84,000	84,000	NUM
american_scientific_journal-766	158	14	to	to	PART
american_scientific_journal-766	158	15	$	$	SYM
american_scientific_journal-766	158	16	168,000	168,000	NUM
american_scientific_journal-766	158	17	for	for	ADP
american_scientific_journal-766	158	18	a	a	DET
american_scientific_journal-766	158	19	course	course	NOUN
american_scientific_journal-766	158	20	of	of	ADP
american_scientific_journal-766	158	21	treatment	treatment	NOUN
american_scientific_journal-766	158	22	in	in	ADP
american_scientific_journal-766	158	23	the	the	DET
american_scientific_journal-766	158	24	8	8	NUM
american_scientific_journal-766	158	25	http://informahealthcare.com/action/dosearch?type=advanced&displaysummary=true&displaysummary=true&field1=keywords&text1=dasabuvir&logicalope1=or&field2=articletitle&text2=dasabuvir&logicalope2=and&field3=all&text3=&search=search&categoryid=41010274&categoryid=40002416&categoryid=40004717&categoryid=40004717&filter=multiple&aftermonth=1&afteryear=&beforemonth=12&beforeyear=&sortby=date&nh=20	http://informahealthcare.com/action/dosearch?type=advanced&displaysummary=true&displaysummary=true&field1=keywords&text1=dasabuvir&logicalope1=or&field2=articletitle&text2=dasabuvir&logicalope2=and&field3=all&text3=&search=search&categoryid=41010274&categoryid=40002416&categoryid=40004717&categoryid=40004717&filter=multiple&aftermonth=1&afteryear=&beforemonth=12&beforeyear=&sortby=date&nh=20	NOUN
american_scientific_journal-766	158	26	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0105	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0105	NOUN
american_scientific_journal-766	158	27	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0115	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23b0115	PROPN
american_scientific_journal-766	159	1	american	american	PROPN
american_scientific_journal-766	159	2	scientific	scientific	PROPN
american_scientific_journal-766	159	3	research	research	PROPN
american_scientific_journal-766	159	4	journal	journal	NOUN
american_scientific_journal-766	159	5	for	for	ADP
american_scientific_journal-766	159	6	engineering	engineering	NOUN
american_scientific_journal-766	159	7	,	,	PUNCT
american_scientific_journal-766	159	8	technology	technology	NOUN
american_scientific_journal-766	159	9	,	,	PUNCT
american_scientific_journal-766	159	10	and	and	CCONJ
american_scientific_journal-766	159	11	sciences	science	NOUN
american_scientific_journal-766	159	12	(	(	PUNCT
american_scientific_journal-766	159	13	asrjets	asrjet	NOUN
american_scientific_journal-766	159	14	)	)	PUNCT
american_scientific_journal-766	159	15	(	(	PUNCT
american_scientific_journal-766	159	16	2015	2015	NUM
american_scientific_journal-766	159	17	)	)	PUNCT
american_scientific_journal-766	159	18	volume	volume	NOUN
american_scientific_journal-766	159	19	13	13	NUM
american_scientific_journal-766	159	20	,	,	PUNCT
american_scientific_journal-766	159	21	no	no	DET
american_scientific_journal-766	159	22	1	1	NUM
american_scientific_journal-766	159	23	,	,	PUNCT
american_scientific_journal-766	159	24	pp	pp	ADV
american_scientific_journal-766	159	25	1	1	NUM
american_scientific_journal-766	159	26	-	-	SYM
american_scientific_journal-766	159	27	23	23	NUM
american_scientific_journal-766	159	28	u.s	u.s	PROPN
american_scientific_journal-766	159	29	.	.	PROPN
american_scientific_journal-766	159	30	,	,	PUNCT
american_scientific_journal-766	159	31	£	£	SYM
american_scientific_journal-766	159	32	35,000	35,000	NUM
american_scientific_journal-766	159	33	for	for	ADP
american_scientific_journal-766	159	34	12	12	NUM
american_scientific_journal-766	159	35	weeks	week	NOUN
american_scientific_journal-766	159	36	in	in	ADP
american_scientific_journal-766	159	37	the	the	DET
american_scientific_journal-766	159	38	uk	uk	PROPN
american_scientific_journal-766	159	39	,	,	PUNCT
american_scientific_journal-766	159	40	has	have	AUX
american_scientific_journal-766	159	41	engendered	engender	VERB
american_scientific_journal-766	159	42	considerable	considerable	ADJ
american_scientific_journal-766	159	43	controversy	controversy	NOUN
american_scientific_journal-766	159	44	.	.	PUNCT
american_scientific_journal-766	160	1	in	in	ADP
american_scientific_journal-766	160	2	september	september	PROPN
american_scientific_journal-766	160	3	2014	2014	NUM
american_scientific_journal-766	160	4	,	,	PUNCT
american_scientific_journal-766	160	5	gilead	gilead	PROPN
american_scientific_journal-766	160	6	announced	announce	VERB
american_scientific_journal-766	160	7	that	that	SCONJ
american_scientific_journal-766	160	8	it	it	PRON
american_scientific_journal-766	160	9	would	would	AUX
american_scientific_journal-766	160	10	permit	permit	VERB
american_scientific_journal-766	160	11	generic	generic	ADJ
american_scientific_journal-766	160	12	manufacturers	manufacturer	NOUN
american_scientific_journal-766	160	13	to	to	PART
american_scientific_journal-766	160	14	sell	sell	VERB
american_scientific_journal-766	160	15	sofosbuvir	sofosbuvir	NOUN
american_scientific_journal-766	160	16	in	in	ADP
american_scientific_journal-766	160	17	91	91	NUM
american_scientific_journal-766	160	18	developing	develop	VERB
american_scientific_journal-766	160	19	countries	country	NOUN
american_scientific_journal-766	160	20	and	and	CCONJ
american_scientific_journal-766	160	21	that	that	SCONJ
american_scientific_journal-766	160	22	it	it	PRON
american_scientific_journal-766	160	23	would	would	AUX
american_scientific_journal-766	160	24	sell	sell	VERB
american_scientific_journal-766	160	25	a	a	DET
american_scientific_journal-766	160	26	name	name	NOUN
american_scientific_journal-766	160	27	brand	brand	NOUN
american_scientific_journal-766	160	28	version	version	NOUN
american_scientific_journal-766	160	29	of	of	ADP
american_scientific_journal-766	160	30	the	the	DET
american_scientific_journal-766	160	31	product	product	NOUN
american_scientific_journal-766	160	32	in	in	ADP
american_scientific_journal-766	160	33	india	india	PROPN
american_scientific_journal-766	160	34	for	for	ADP
american_scientific_journal-766	160	35	approximately	approximately	ADV
american_scientific_journal-766	160	36	$	$	SYM
american_scientific_journal-766	160	37	300	300	NUM
american_scientific_journal-766	160	38	per	per	ADP
american_scientific_journal-766	160	39	course	course	NOUN
american_scientific_journal-766	160	40	of	of	ADP
american_scientific_journal-766	160	41	treatment	treatment	NOUN
american_scientific_journal-766	160	42	[	[	X
american_scientific_journal-766	160	43	61	61	NUM
american_scientific_journal-766	160	44	]	]	SYM
american_scientific_journal-766	160	45	.	.	PUNCT
american_scientific_journal-766	161	1	2.2.4	2.2.4	NUM
american_scientific_journal-766	161	2	.	.	PUNCT
american_scientific_journal-766	161	3	mechanism	mechanism	NOUN
american_scientific_journal-766	161	4	of	of	ADP
american_scientific_journal-766	161	5	actions	action	NOUN
american_scientific_journal-766	161	6	of	of	ADP
american_scientific_journal-766	161	7	antiviral	antiviral	ADJ
american_scientific_journal-766	161	8	drugs	drug	NOUN
american_scientific_journal-766	161	9	2.2.4.1	2.2.4.1	NUM
american_scientific_journal-766	161	10	.	.	PUNCT
american_scientific_journal-766	162	1	anti	anti	ADJ
american_scientific_journal-766	162	2	-	-	ADJ
american_scientific_journal-766	162	3	hcv	hcv	ADJ
american_scientific_journal-766	162	4	mechanisms	mechanism	NOUN
american_scientific_journal-766	162	5	of	of	ADP
american_scientific_journal-766	162	6	interferon	interferon	NOUN
american_scientific_journal-766	162	7	these	these	PRON
american_scientific_journal-766	162	8	are	be	AUX
american_scientific_journal-766	162	9	glycoproteins	glycoprotein	NOUN
american_scientific_journal-766	162	10	of	of	ADP
american_scientific_journal-766	162	11	low	low	ADJ
american_scientific_journal-766	162	12	molecular	molecular	ADJ
american_scientific_journal-766	162	13	weight	weight	NOUN
american_scientific_journal-766	162	14	produced	produce	VERB
american_scientific_journal-766	162	15	by	by	ADP
american_scientific_journal-766	162	16	fibroblasts	fibroblast	NOUN
american_scientific_journal-766	162	17	,	,	PUNCT
american_scientific_journal-766	162	18	epithelial	epithelial	ADJ
american_scientific_journal-766	162	19	cells	cell	NOUN
american_scientific_journal-766	162	20	hepatocytes	hepatocyte	NOUN
american_scientific_journal-766	162	21	and	and	CCONJ
american_scientific_journal-766	162	22	predominantly	predominantly	ADV
american_scientific_journal-766	162	23	dendritic	dendritic	ADJ
american_scientific_journal-766	162	24	cells	cell	NOUN
american_scientific_journal-766	162	25	in	in	ADP
american_scientific_journal-766	162	26	response	response	NOUN
american_scientific_journal-766	162	27	to	to	ADP
american_scientific_journal-766	162	28	various	various	ADJ
american_scientific_journal-766	162	29	pathogens	pathogen	NOUN
american_scientific_journal-766	162	30	like	like	ADP
american_scientific_journal-766	162	31	virus	virus	NOUN
american_scientific_journal-766	162	32	,	,	PUNCT
american_scientific_journal-766	162	33	tumor	tumor	NOUN
american_scientific_journal-766	162	34	cells	cell	NOUN
american_scientific_journal-766	162	35	,	,	PUNCT
american_scientific_journal-766	162	36	bacteria	bacteria	NOUN
american_scientific_journal-766	162	37	,	,	PUNCT
american_scientific_journal-766	162	38	parasites	parasite	NOUN
american_scientific_journal-766	162	39	.	.	PUNCT
american_scientific_journal-766	163	1	it	it	PRON
american_scientific_journal-766	163	2	is	be	AUX
american_scientific_journal-766	163	3	the	the	DET
american_scientific_journal-766	163	4	first	first	ADJ
american_scientific_journal-766	163	5	drug	drug	NOUN
american_scientific_journal-766	163	6	approved	approve	VERB
american_scientific_journal-766	163	7	by	by	ADP
american_scientific_journal-766	163	8	fda	fda	PROPN
american_scientific_journal-766	163	9	to	to	PART
american_scientific_journal-766	163	10	treat	treat	VERB
american_scientific_journal-766	163	11	hepatitis	hepatitis	PROPN
american_scientific_journal-766	163	12	c	c	PROPN
american_scientific_journal-766	163	13	(	(	PUNCT
american_scientific_journal-766	163	14	ifn	ifn	PROPN
american_scientific_journal-766	163	15	-	-	PUNCT
american_scientific_journal-766	163	16	α	α	NOUN
american_scientific_journal-766	163	17	got	get	VERB
american_scientific_journal-766	163	18	fda	fda	PROPN
american_scientific_journal-766	163	19	approval	approval	NOUN
american_scientific_journal-766	163	20	in	in	ADP
american_scientific_journal-766	163	21	1991	1991	NUM
american_scientific_journal-766	163	22	)	)	PUNCT
american_scientific_journal-766	163	23	.	.	PUNCT
american_scientific_journal-766	164	1	there	there	PRON
american_scientific_journal-766	164	2	are	be	VERB
american_scientific_journal-766	164	3	several	several	ADJ
american_scientific_journal-766	164	4	types	type	NOUN
american_scientific_journal-766	164	5	of	of	ADP
american_scientific_journal-766	164	6	ifns	ifns	NOUN
american_scientific_journal-766	164	7	grouped	group	VERB
american_scientific_journal-766	164	8	into	into	ADP
american_scientific_journal-766	164	9	three	three	NUM
american_scientific_journal-766	164	10	types	type	NOUN
american_scientific_journal-766	164	11	(	(	PUNCT
american_scientific_journal-766	164	12	types	type	NOUN
american_scientific_journal-766	164	13	i	i	PRON
american_scientific_journal-766	164	14	,	,	PUNCT
american_scientific_journal-766	164	15	ii	ii	PROPN
american_scientific_journal-766	164	16	and	and	CCONJ
american_scientific_journal-766	164	17	iii	iii	NOUN
american_scientific_journal-766	164	18	)	)	PUNCT
american_scientific_journal-766	164	19	,	,	PUNCT
american_scientific_journal-766	164	20	type	type	NOUN
american_scientific_journal-766	164	21	i	i	PRON
american_scientific_journal-766	164	22	(	(	PUNCT
american_scientific_journal-766	164	23	α	α	NOUN
american_scientific_journal-766	164	24	and	and	CCONJ
american_scientific_journal-766	164	25	β	β	NOUN
american_scientific_journal-766	164	26	)	)	PUNCT
american_scientific_journal-766	164	27	and	and	CCONJ
american_scientific_journal-766	164	28	type	type	PROPN
american_scientific_journal-766	164	29	ii	ii	PROPN
american_scientific_journal-766	164	30	(	(	PUNCT
american_scientific_journal-766	164	31	gamma	gamma	NOUN
american_scientific_journal-766	164	32	)	)	PUNCT
american_scientific_journal-766	164	33	exhibits	exhibit	VERB
american_scientific_journal-766	164	34	significant	significant	ADJ
american_scientific_journal-766	164	35	activity	activity	NOUN
american_scientific_journal-766	164	36	and	and	CCONJ
american_scientific_journal-766	164	37	hence	hence	ADV
american_scientific_journal-766	164	38	ifn	ifn	PROPN
american_scientific_journal-766	164	39	-	-	PUNCT
american_scientific_journal-766	164	40	α2a	α2a	NOUN
american_scientific_journal-766	164	41	and	and	CCONJ
american_scientific_journal-766	164	42	2b	2b	NOUN
american_scientific_journal-766	164	43	produced	produce	VERB
american_scientific_journal-766	164	44	by	by	ADP
american_scientific_journal-766	164	45	recombinant	recombinant	ADJ
american_scientific_journal-766	164	46	dna	dna	PROPN
american_scientific_journal-766	164	47	technology	technology	NOUN
american_scientific_journal-766	164	48	used	use	VERB
american_scientific_journal-766	164	49	commercially	commercially	ADV
american_scientific_journal-766	164	50	[	[	X
american_scientific_journal-766	164	51	33	33	NUM
american_scientific_journal-766	164	52	]	]	PUNCT
american_scientific_journal-766	164	53	.	.	PUNCT
american_scientific_journal-766	165	1	pegylated	pegylate	VERB
american_scientific_journal-766	165	2	(	(	PUNCT
american_scientific_journal-766	165	3	peg	peg	NOUN
american_scientific_journal-766	165	4	)	)	PUNCT
american_scientific_journal-766	165	5	ifn	ifn	PROPN
american_scientific_journal-766	165	6	-	-	PUNCT
american_scientific_journal-766	165	7	α2a	α2a	NOUN
american_scientific_journal-766	165	8	is	be	AUX
american_scientific_journal-766	165	9	absorbed	absorb	VERB
american_scientific_journal-766	165	10	slowly	slowly	ADV
american_scientific_journal-766	165	11	and	and	CCONJ
american_scientific_journal-766	165	12	sustained	sustain	VERB
american_scientific_journal-766	165	13	twice	twice	ADV
american_scientific_journal-766	165	14	longer	long	ADV
american_scientific_journal-766	165	15	in	in	ADP
american_scientific_journal-766	165	16	plasma	plasma	NOUN
american_scientific_journal-766	165	17	compared	compare	VERB
american_scientific_journal-766	165	18	to	to	ADP
american_scientific_journal-766	165	19	ifn	ifn	NOUN
american_scientific_journal-766	165	20	-	-	PUNCT
american_scientific_journal-766	165	21	α2b	α2b	NOUN
american_scientific_journal-766	165	22	.	.	PUNCT
american_scientific_journal-766	166	1	ifn	ifn	NOUN
american_scientific_journal-766	166	2	receptors	receptor	NOUN
american_scientific_journal-766	166	3	have	have	VERB
american_scientific_journal-766	166	4	jak	jak	PROPN
american_scientific_journal-766	166	5	-	-	PUNCT
american_scientific_journal-766	166	6	stat	stat	PROPN
american_scientific_journal-766	166	7	(	(	PUNCT
american_scientific_journal-766	166	8	janus	janus	PROPN
american_scientific_journal-766	166	9	kinase	kinase	PROPN
american_scientific_journal-766	166	10	-	-	PUNCT
american_scientific_journal-766	166	11	signal	signal	NOUN
american_scientific_journal-766	166	12	transduction	transduction	NOUN
american_scientific_journal-766	166	13	and	and	CCONJ
american_scientific_journal-766	166	14	transducer	transducer	NOUN
american_scientific_journal-766	166	15	mechanism	mechanism	NOUN
american_scientific_journal-766	166	16	)	)	PUNCT
american_scientific_journal-766	166	17	signaling	signal	VERB
american_scientific_journal-766	166	18	pathway	pathway	NOUN
american_scientific_journal-766	166	19	.	.	PUNCT
american_scientific_journal-766	167	1	the	the	DET
american_scientific_journal-766	167	2	phosphorylated	phosphorylate	VERB
american_scientific_journal-766	167	3	stat	stat	NOUN
american_scientific_journal-766	167	4	binds	bind	VERB
american_scientific_journal-766	167	5	with	with	ADP
american_scientific_journal-766	167	6	p48	p48	NOUN
american_scientific_journal-766	167	7	protein	protein	NOUN
american_scientific_journal-766	167	8	and	and	CCONJ
american_scientific_journal-766	167	9	forms	form	VERB
american_scientific_journal-766	167	10	an	an	DET
american_scientific_journal-766	167	11	isgf-3	isgf-3	NOUN
american_scientific_journal-766	167	12	(	(	PUNCT
american_scientific_journal-766	167	13	ifn	ifn	NOUN
american_scientific_journal-766	167	14	-	-	PUNCT
american_scientific_journal-766	167	15	stimulated	stimulate	VERB
american_scientific_journal-766	167	16	gene	gene	NOUN
american_scientific_journal-766	167	17	factor-3	factor-3	PROPN
american_scientific_journal-766	167	18	)	)	PUNCT
american_scientific_journal-766	167	19	which	which	PRON
american_scientific_journal-766	167	20	in	in	ADP
american_scientific_journal-766	167	21	turn	turn	NOUN
american_scientific_journal-766	167	22	enters	enter	VERB
american_scientific_journal-766	167	23	into	into	ADP
american_scientific_journal-766	167	24	nucleus	nucleus	NOUN
american_scientific_journal-766	167	25	,	,	PUNCT
american_scientific_journal-766	167	26	stimulating	stimulate	VERB
american_scientific_journal-766	167	27	ifn	ifn	NOUN
american_scientific_journal-766	167	28	-	-	PUNCT
american_scientific_journal-766	167	29	stimulated	stimulate	VERB
american_scientific_journal-766	167	30	regulatory	regulatory	ADJ
american_scientific_journal-766	167	31	element	element	NOUN
american_scientific_journal-766	167	32	leading	lead	VERB
american_scientific_journal-766	167	33	to	to	ADP
american_scientific_journal-766	167	34	synthesis	synthesis	NOUN
american_scientific_journal-766	167	35	of	of	ADP
american_scientific_journal-766	167	36	various	various	ADJ
american_scientific_journal-766	167	37	proteins	protein	NOUN
american_scientific_journal-766	167	38	which	which	PRON
american_scientific_journal-766	167	39	interfere	interfere	VERB
american_scientific_journal-766	167	40	in	in	ADP
american_scientific_journal-766	167	41	viral	viral	ADJ
american_scientific_journal-766	167	42	penetration	penetration	NOUN
american_scientific_journal-766	167	43	,	,	PUNCT
american_scientific_journal-766	167	44	synthesis	synthesis	NOUN
american_scientific_journal-766	167	45	of	of	ADP
american_scientific_journal-766	167	46	viral	viral	ADJ
american_scientific_journal-766	167	47	m	m	NOUN
american_scientific_journal-766	167	48	-	-	NOUN
american_scientific_journal-766	167	49	rna	rna	NOUN
american_scientific_journal-766	167	50	,	,	PUNCT
american_scientific_journal-766	167	51	assembly	assembly	NOUN
american_scientific_journal-766	167	52	of	of	ADP
american_scientific_journal-766	167	53	viral	viral	ADJ
american_scientific_journal-766	167	54	particles	particle	NOUN
american_scientific_journal-766	167	55	and	and	CCONJ
american_scientific_journal-766	167	56	its	its	PRON
american_scientific_journal-766	167	57	release	release	NOUN
american_scientific_journal-766	167	58	(	(	PUNCT
american_scientific_journal-766	167	59	figure	figure	NOUN
american_scientific_journal-766	167	60	3	3	NUM
american_scientific_journal-766	167	61	)	)	PUNCT
american_scientific_journal-766	168	1	[	[	X
american_scientific_journal-766	168	2	62	62	NUM
american_scientific_journal-766	168	3	]	]	PUNCT
american_scientific_journal-766	168	4	.	.	PUNCT
american_scientific_journal-766	169	1	figure	figure	VERB
american_scientific_journal-766	169	2	2	2	NUM
american_scientific_journal-766	169	3	:	:	PUNCT
american_scientific_journal-766	169	4	mechanism	mechanism	NOUN
american_scientific_journal-766	169	5	of	of	ADP
american_scientific_journal-766	169	6	action	action	NOUN
american_scientific_journal-766	169	7	of	of	ADP
american_scientific_journal-766	169	8	ifn	ifn	NOUN
american_scientific_journal-766	169	9	in	in	ADP
american_scientific_journal-766	169	10	hcv	hcv	NOUN
american_scientific_journal-766	169	11	infection	infection	NOUN
american_scientific_journal-766	169	12	(	(	PUNCT
american_scientific_journal-766	169	13	red	red	ADJ
american_scientific_journal-766	169	14	arrow	arrow	NOUN
american_scientific_journal-766	169	15	=	=	NOUN
american_scientific_journal-766	169	16	inhibition	inhibition	NOUN
american_scientific_journal-766	169	17	,	,	PUNCT
american_scientific_journal-766	169	18	green	green	ADJ
american_scientific_journal-766	169	19	arrow	arrow	NOUN
american_scientific_journal-766	169	20	=	=	SYM
american_scientific_journal-766	169	21	stimulation	stimulation	NOUN
american_scientific_journal-766	169	22	)	)	PUNCT
american_scientific_journal-766	169	23	.	.	PUNCT
american_scientific_journal-766	170	1	2.2.4.2	2.2.4.2	NUM
american_scientific_journal-766	170	2	.	.	PUNCT
american_scientific_journal-766	170	3	mechanism	mechanism	NOUN
american_scientific_journal-766	170	4	of	of	ADP
american_scientific_journal-766	170	5	action	action	NOUN
american_scientific_journal-766	170	6	of	of	ADP
american_scientific_journal-766	170	7	ribavirin	ribavirin	NOUN
american_scientific_journal-766	170	8	the	the	DET
american_scientific_journal-766	170	9	addition	addition	NOUN
american_scientific_journal-766	170	10	of	of	ADP
american_scientific_journal-766	170	11	ribavirin	ribavirin	NOUN
american_scientific_journal-766	170	12	to	to	ADP
american_scientific_journal-766	170	13	ifn	ifn	PROPN
american_scientific_journal-766	170	14	-	-	PUNCT
american_scientific_journal-766	170	15	α	α	NOUN
american_scientific_journal-766	170	16	–	–	PUNCT
american_scientific_journal-766	170	17	based	base	VERB
american_scientific_journal-766	170	18	regimens	regimen	NOUN
american_scientific_journal-766	170	19	produces	produce	VERB
american_scientific_journal-766	170	20	dramatic	dramatic	ADJ
american_scientific_journal-766	170	21	improvement	improvement	NOUN
american_scientific_journal-766	170	22	in	in	ADP
american_scientific_journal-766	170	23	svr	svr	PROPN
american_scientific_journal-766	170	24	rates	rate	NOUN
american_scientific_journal-766	170	25	among	among	ADP
american_scientific_journal-766	170	26	patients	patient	NOUN
american_scientific_journal-766	170	27	with	with	ADP
american_scientific_journal-766	170	28	chronic	chronic	ADJ
american_scientific_journal-766	170	29	hepatitis	hepatitis	PROPN
american_scientific_journal-766	170	30	c.	c.	PROPN
american_scientific_journal-766	170	31	clinically	clinically	ADV
american_scientific_journal-766	170	32	;	;	PUNCT
american_scientific_journal-766	170	33	ribavirin	ribavirin	NOUN
american_scientific_journal-766	170	34	appears	appear	VERB
american_scientific_journal-766	170	35	both	both	PRON
american_scientific_journal-766	170	36	to	to	PART
american_scientific_journal-766	170	37	increase	increase	VERB
american_scientific_journal-766	170	38	the	the	DET
american_scientific_journal-766	170	39	end	end	NOUN
american_scientific_journal-766	170	40	-	-	PUNCT
american_scientific_journal-766	170	41	of	of	ADP
american_scientific_journal-766	170	42	-	-	PUNCT
american_scientific_journal-766	170	43	treatment	treatment	NOUN
american_scientific_journal-766	170	44	response	response	NOUN
american_scientific_journal-766	170	45	rate	rate	NOUN
american_scientific_journal-766	170	46	and	and	CCONJ
american_scientific_journal-766	170	47	to	to	PART
american_scientific_journal-766	170	48	decrease	decrease	VERB
american_scientific_journal-766	170	49	the	the	DET
american_scientific_journal-766	170	50	subsequent	subsequent	ADJ
american_scientific_journal-766	170	51	relapse	relapse	NOUN
american_scientific_journal-766	170	52	rate	rate	NOUN
american_scientific_journal-766	170	53	(	(	PUNCT
american_scientific_journal-766	170	54	figure	figure	NOUN
american_scientific_journal-766	170	55	3	3	NUM
american_scientific_journal-766	170	56	)	)	PUNCT
american_scientific_journal-766	170	57	.	.	PUNCT
american_scientific_journal-766	171	1	it	it	PRON
american_scientific_journal-766	171	2	is	be	AUX
american_scientific_journal-766	171	3	a	a	DET
american_scientific_journal-766	171	4	synthetic	synthetic	ADJ
american_scientific_journal-766	171	5	guanosine	guanosine	NOUN
american_scientific_journal-766	171	6	analog	analog	NOUN
american_scientific_journal-766	171	7	with	with	ADP
american_scientific_journal-766	171	8	a	a	DET
american_scientific_journal-766	171	9	broad	broad	ADJ
american_scientific_journal-766	171	10	spectrum	spectrum	NOUN
american_scientific_journal-766	171	11	of	of	ADP
american_scientific_journal-766	171	12	antiviral	antiviral	ADJ
american_scientific_journal-766	171	13	activity	activity	NOUN
american_scientific_journal-766	171	14	,	,	PUNCT
american_scientific_journal-766	171	15	administered	administer	VERB
american_scientific_journal-766	171	16	along	along	ADP
american_scientific_journal-766	171	17	with	with	ADP
american_scientific_journal-766	171	18	ifn	ifn	PROPN
american_scientific_journal-766	171	19	at	at	ADP
american_scientific_journal-766	171	20	a	a	DET
american_scientific_journal-766	171	21	dose	dose	NOUN
american_scientific_journal-766	171	22	of	of	ADP
american_scientific_journal-766	171	23	800	800	NUM
american_scientific_journal-766	171	24	-	-	SYM
american_scientific_journal-766	171	25	1200	1200	NUM
american_scientific_journal-766	171	26	mg	mg	PROPN
american_scientific_journal-766	171	27	/	/	SYM
american_scientific_journal-766	171	28	day	day	NOUN
american_scientific_journal-766	171	29	with	with	ADP
american_scientific_journal-766	171	30	an	an	DET
american_scientific_journal-766	171	31	oral	oral	ADJ
american_scientific_journal-766	171	32	bioavailability	bioavailability	NOUN
american_scientific_journal-766	171	33	of	of	ADP
american_scientific_journal-766	171	34	50	50	NUM
american_scientific_journal-766	171	35	%	%	NOUN
american_scientific_journal-766	171	36	and	and	CCONJ
american_scientific_journal-766	171	37	an	an	DET
american_scientific_journal-766	171	38	elimination	elimination	NOUN
american_scientific_journal-766	171	39	half	half	ADJ
american_scientific_journal-766	171	40	-	-	PUNCT
american_scientific_journal-766	171	41	life	life	NOUN
american_scientific_journal-766	171	42	of	of	ADP
american_scientific_journal-766	171	43	>	>	SYM
american_scientific_journal-766	171	44	10	10	NUM
american_scientific_journal-766	171	45	days	day	NOUN
american_scientific_journal-766	171	46	[	[	X
american_scientific_journal-766	171	47	33	33	NUM
american_scientific_journal-766	171	48	]	]	PUNCT
american_scientific_journal-766	171	49	.	.	PUNCT
american_scientific_journal-766	172	1	when	when	SCONJ
american_scientific_journal-766	172	2	combined	combine	VERB
american_scientific_journal-766	172	3	with	with	ADP
american_scientific_journal-766	172	4	standard	standard	ADJ
american_scientific_journal-766	172	5	ifn	ifn	PROPN
american_scientific_journal-766	172	6	-	-	PUNCT
american_scientific_journal-766	172	7	α	α	NOUN
american_scientific_journal-766	172	8	,	,	PUNCT
american_scientific_journal-766	172	9	9	9	NUM
american_scientific_journal-766	172	10	american	american	ADJ
american_scientific_journal-766	172	11	scientific	scientific	ADJ
american_scientific_journal-766	172	12	research	research	NOUN
american_scientific_journal-766	172	13	journal	journal	NOUN
american_scientific_journal-766	172	14	for	for	ADP
american_scientific_journal-766	172	15	engineering	engineering	NOUN
american_scientific_journal-766	172	16	,	,	PUNCT
american_scientific_journal-766	172	17	technology	technology	NOUN
american_scientific_journal-766	172	18	,	,	PUNCT
american_scientific_journal-766	172	19	and	and	CCONJ
american_scientific_journal-766	172	20	sciences	science	NOUN
american_scientific_journal-766	172	21	(	(	PUNCT
american_scientific_journal-766	172	22	asrjets	asrjet	NOUN
american_scientific_journal-766	172	23	)	)	PUNCT
american_scientific_journal-766	172	24	(	(	PUNCT
american_scientific_journal-766	172	25	2015	2015	NUM
american_scientific_journal-766	172	26	)	)	PUNCT
american_scientific_journal-766	172	27	volume	volume	NOUN
american_scientific_journal-766	172	28	13	13	NUM
american_scientific_journal-766	172	29	,	,	PUNCT
american_scientific_journal-766	172	30	no	no	DET
american_scientific_journal-766	172	31	1	1	NUM
american_scientific_journal-766	172	32	,	,	PUNCT
american_scientific_journal-766	172	33	pp	pp	ADV
american_scientific_journal-766	172	34	1	1	NUM
american_scientific_journal-766	172	35	-	-	SYM
american_scientific_journal-766	172	36	23	23	NUM
american_scientific_journal-766	172	37	ribavirin	ribavirin	NOUN
american_scientific_journal-766	172	38	appears	appear	VERB
american_scientific_journal-766	172	39	to	to	PART
american_scientific_journal-766	172	40	increase	increase	VERB
american_scientific_journal-766	172	41	the	the	DET
american_scientific_journal-766	172	42	second	second	ADJ
american_scientific_journal-766	172	43	phase	phase	NOUN
american_scientific_journal-766	172	44	decline	decline	NOUN
american_scientific_journal-766	172	45	in	in	ADP
american_scientific_journal-766	172	46	hcv	hcv	PROPN
american_scientific_journal-766	172	47	rna	rna	NOUN
american_scientific_journal-766	172	48	levels	level	NOUN
american_scientific_journal-766	172	49	;	;	PUNCT
american_scientific_journal-766	172	50	however	however	ADV
american_scientific_journal-766	172	51	,	,	PUNCT
american_scientific_journal-766	172	52	this	this	DET
american_scientific_journal-766	172	53	effect	effect	NOUN
american_scientific_journal-766	172	54	is	be	AUX
american_scientific_journal-766	172	55	slight	slight	ADJ
american_scientific_journal-766	172	56	and	and	CCONJ
american_scientific_journal-766	172	57	is	be	AUX
american_scientific_journal-766	172	58	not	not	PART
american_scientific_journal-766	172	59	observed	observe	VERB
american_scientific_journal-766	172	60	when	when	SCONJ
american_scientific_journal-766	172	61	standard	standard	ADJ
american_scientific_journal-766	172	62	ifn	ifn	NOUN
american_scientific_journal-766	172	63	is	be	AUX
american_scientific_journal-766	172	64	given	give	VERB
american_scientific_journal-766	172	65	daily	daily	ADJ
american_scientific_journal-766	172	66	or	or	CCONJ
american_scientific_journal-766	172	67	peg	peg	NOUN
american_scientific_journal-766	172	68	-	-	PUNCT
american_scientific_journal-766	172	69	interferon	interferon	NOUN
american_scientific_journal-766	172	70	is	be	AUX
american_scientific_journal-766	172	71	used	use	VERB
american_scientific_journal-766	172	72	.	.	PUNCT
american_scientific_journal-766	173	1	these	these	DET
american_scientific_journal-766	173	2	results	result	NOUN
american_scientific_journal-766	173	3	suggest	suggest	VERB
american_scientific_journal-766	173	4	that	that	SCONJ
american_scientific_journal-766	173	5	ribavirin	ribavirin	NOUN
american_scientific_journal-766	173	6	does	do	AUX
american_scientific_journal-766	173	7	not	not	PART
american_scientific_journal-766	173	8	have	have	VERB
american_scientific_journal-766	173	9	direct	direct	ADJ
american_scientific_journal-766	173	10	antiviral	antiviral	ADJ
american_scientific_journal-766	173	11	activity	activity	NOUN
american_scientific_journal-766	173	12	against	against	ADP
american_scientific_journal-766	173	13	hcv	hcv	PROPN
american_scientific_journal-766	173	14	.	.	PUNCT
american_scientific_journal-766	174	1	although	although	SCONJ
american_scientific_journal-766	174	2	ribavirin	ribavirin	NOUN
american_scientific_journal-766	174	3	is	be	AUX
american_scientific_journal-766	174	4	an	an	DET
american_scientific_journal-766	174	5	impdh	impdh	NOUN
american_scientific_journal-766	174	6	inhibitor	inhibitor	NOUN
american_scientific_journal-766	174	7	,	,	PUNCT
american_scientific_journal-766	174	8	there	there	PRON
american_scientific_journal-766	174	9	is	be	VERB
american_scientific_journal-766	174	10	little	little	ADJ
american_scientific_journal-766	174	11	clinical	clinical	ADJ
american_scientific_journal-766	174	12	data	datum	NOUN
american_scientific_journal-766	174	13	to	to	PART
american_scientific_journal-766	174	14	support	support	VERB
american_scientific_journal-766	174	15	this	this	DET
american_scientific_journal-766	174	16	mechanism	mechanism	NOUN
american_scientific_journal-766	174	17	of	of	ADP
american_scientific_journal-766	174	18	action	action	NOUN
american_scientific_journal-766	174	19	.	.	PUNCT
american_scientific_journal-766	175	1	other	other	ADJ
american_scientific_journal-766	175	2	impdh	impdh	NOUN
american_scientific_journal-766	175	3	inhibitors	inhibitor	NOUN
american_scientific_journal-766	175	4	have	have	AUX
american_scientific_journal-766	175	5	failed	fail	VERB
american_scientific_journal-766	175	6	to	to	PART
american_scientific_journal-766	175	7	demonstrate	demonstrate	VERB
american_scientific_journal-766	175	8	antiviral	antiviral	ADJ
american_scientific_journal-766	175	9	activity	activity	NOUN
american_scientific_journal-766	175	10	in	in	ADP
american_scientific_journal-766	175	11	vivo	vivo	NOUN
american_scientific_journal-766	175	12	against	against	ADP
american_scientific_journal-766	175	13	hcv	hcv	NOUN
american_scientific_journal-766	175	14	either	either	CCONJ
american_scientific_journal-766	175	15	alone	alone	ADJ
american_scientific_journal-766	175	16	or	or	CCONJ
american_scientific_journal-766	175	17	in	in	ADP
american_scientific_journal-766	175	18	combination	combination	NOUN
american_scientific_journal-766	175	19	with	with	ADP
american_scientific_journal-766	175	20	ribavirin	ribavirin	NOUN
american_scientific_journal-766	175	21	[	[	X
american_scientific_journal-766	175	22	63	63	NUM
american_scientific_journal-766	175	23	]	]	PUNCT
american_scientific_journal-766	175	24	.	.	PUNCT
american_scientific_journal-766	176	1	figure	figure	VERB
american_scientific_journal-766	176	2	3	3	NUM
american_scientific_journal-766	176	3	:	:	PUNCT
american_scientific_journal-766	176	4	mechanism	mechanism	NOUN
american_scientific_journal-766	176	5	of	of	ADP
american_scientific_journal-766	176	6	action	action	NOUN
american_scientific_journal-766	176	7	of	of	ADP
american_scientific_journal-766	176	8	ribavirin	ribavirin	NOUN
american_scientific_journal-766	176	9	in	in	ADP
american_scientific_journal-766	176	10	hcv	hcv	ADJ
american_scientific_journal-766	176	11	infection	infection	NOUN
american_scientific_journal-766	176	12	(	(	PUNCT
american_scientific_journal-766	176	13	red	red	ADJ
american_scientific_journal-766	176	14	arrow	arrow	NOUN
american_scientific_journal-766	176	15	=	=	NOUN
american_scientific_journal-766	176	16	inhibition	inhibition	NOUN
american_scientific_journal-766	176	17	,	,	PUNCT
american_scientific_journal-766	176	18	green	green	ADJ
american_scientific_journal-766	176	19	arrow	arrow	NOUN
american_scientific_journal-766	176	20	=	=	SYM
american_scientific_journal-766	176	21	stimulation	stimulation	NOUN
american_scientific_journal-766	176	22	)	)	PUNCT
american_scientific_journal-766	176	23	.	.	PUNCT
american_scientific_journal-766	177	1	2.2.4.3	2.2.4.3	X
american_scientific_journal-766	177	2	.	.	PUNCT
american_scientific_journal-766	177	3	mechanism	mechanism	NOUN
american_scientific_journal-766	177	4	of	of	ADP
american_scientific_journal-766	177	5	action	action	NOUN
american_scientific_journal-766	177	6	of	of	ADP
american_scientific_journal-766	177	7	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	177	8	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	177	9	is	be	AUX
american_scientific_journal-766	177	10	a	a	DET
american_scientific_journal-766	177	11	protide	protide	ADJ
american_scientific_journal-766	177	12	prodrug	prodrug	NOUN
american_scientific_journal-766	177	13	metabolized	metabolize	VERB
american_scientific_journal-766	177	14	to	to	ADP
american_scientific_journal-766	177	15	the	the	DET
american_scientific_journal-766	177	16	active	active	ADJ
american_scientific_journal-766	177	17	antiviral	antiviral	ADJ
american_scientific_journal-766	177	18	agent	agent	NOUN
american_scientific_journal-766	177	19	2'-deoxy-2'-α	2'-deoxy-2'-α	NUM
american_scientific_journal-766	177	20	-	-	PUNCT
american_scientific_journal-766	177	21	fluoro	fluoro	NOUN
american_scientific_journal-766	177	22	-	-	PUNCT
american_scientific_journal-766	177	23	β	β	NOUN
american_scientific_journal-766	177	24	-	-	NOUN
american_scientific_journal-766	177	25	cmethyluridine-5'-triphosphate	cmethyluridine-5'-triphosphate	NOUN
american_scientific_journal-766	177	26	.	.	PUNCT
american_scientific_journal-766	178	1	the	the	DET
american_scientific_journal-766	178	2	triphosphate	triphosphate	NOUN
american_scientific_journal-766	178	3	serves	serve	VERB
american_scientific_journal-766	178	4	as	as	ADP
american_scientific_journal-766	178	5	a	a	DET
american_scientific_journal-766	178	6	defective	defective	ADJ
american_scientific_journal-766	178	7	substrate	substrate	NOUN
american_scientific_journal-766	178	8	for	for	ADP
american_scientific_journal-766	178	9	the	the	DET
american_scientific_journal-766	178	10	ns5b	ns5b	ADJ
american_scientific_journal-766	178	11	protein	protein	NOUN
american_scientific_journal-766	178	12	,	,	PUNCT
american_scientific_journal-766	178	13	which	which	PRON
american_scientific_journal-766	178	14	is	be	AUX
american_scientific_journal-766	178	15	the	the	DET
american_scientific_journal-766	178	16	viral	viral	ADJ
american_scientific_journal-766	178	17	rna	rna	NOUN
american_scientific_journal-766	178	18	polymerase	polymerase	NOUN
american_scientific_journal-766	178	19	,	,	PUNCT
american_scientific_journal-766	178	20	thus	thus	ADV
american_scientific_journal-766	178	21	acts	act	VERB
american_scientific_journal-766	178	22	as	as	ADP
american_scientific_journal-766	178	23	an	an	DET
american_scientific_journal-766	178	24	inhibitor	inhibitor	NOUN
american_scientific_journal-766	178	25	of	of	ADP
american_scientific_journal-766	178	26	viral	viral	ADJ
american_scientific_journal-766	178	27	rna	rna	NOUN
american_scientific_journal-766	178	28	synthesis	synthesis	NOUN
american_scientific_journal-766	178	29	[	[	X
american_scientific_journal-766	178	30	64	64	NUM
american_scientific_journal-766	178	31	]	]	PUNCT
american_scientific_journal-766	178	32	.	.	PUNCT
american_scientific_journal-766	179	1	the	the	DET
american_scientific_journal-766	179	2	active	active	ADJ
american_scientific_journal-766	179	3	substance	substance	NOUN
american_scientific_journal-766	179	4	in	in	ADP
american_scientific_journal-766	179	5	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	179	6	,	,	PUNCT
american_scientific_journal-766	179	7	blocks	block	VERB
american_scientific_journal-766	179	8	the	the	DET
american_scientific_journal-766	179	9	action	action	NOUN
american_scientific_journal-766	179	10	of	of	ADP
american_scientific_journal-766	179	11	an	an	DET
american_scientific_journal-766	179	12	enzyme	enzyme	NOUN
american_scientific_journal-766	179	13	called	call	VERB
american_scientific_journal-766	179	14	‘	'	PUNCT
american_scientific_journal-766	179	15	ns5b	ns5b	ADJ
american_scientific_journal-766	179	16	rna	rna	NOUN
american_scientific_journal-766	179	17	-	-	PUNCT
american_scientific_journal-766	179	18	dependent	dependent	ADJ
american_scientific_journal-766	179	19	rna	rna	NOUN
american_scientific_journal-766	179	20	polymerase	polymerase	NOUN
american_scientific_journal-766	179	21	’	'	PUNCT
american_scientific_journal-766	179	22	in	in	ADP
american_scientific_journal-766	179	23	the	the	DET
american_scientific_journal-766	179	24	hepatitis	hepatitis	PROPN
american_scientific_journal-766	179	25	c	c	PROPN
american_scientific_journal-766	179	26	virus	virus	PROPN
american_scientific_journal-766	179	27	,	,	PUNCT
american_scientific_journal-766	179	28	which	which	PRON
american_scientific_journal-766	179	29	is	be	AUX
american_scientific_journal-766	179	30	essential	essential	ADJ
american_scientific_journal-766	179	31	for	for	SCONJ
american_scientific_journal-766	179	32	the	the	DET
american_scientific_journal-766	179	33	virus	virus	NOUN
american_scientific_journal-766	179	34	to	to	PART
american_scientific_journal-766	179	35	multiply	multiply	VERB
american_scientific_journal-766	179	36	.	.	PUNCT
american_scientific_journal-766	180	1	this	this	PRON
american_scientific_journal-766	180	2	stops	stop	VERB
american_scientific_journal-766	180	3	the	the	DET
american_scientific_journal-766	180	4	hepatitis	hepatitis	PROPN
american_scientific_journal-766	180	5	c	c	PROPN
american_scientific_journal-766	180	6	virus	virus	NOUN
american_scientific_journal-766	180	7	from	from	ADP
american_scientific_journal-766	180	8	multiplying	multiply	VERB
american_scientific_journal-766	180	9	and	and	CCONJ
american_scientific_journal-766	180	10	infecting	infect	VERB
american_scientific_journal-766	180	11	new	new	ADJ
american_scientific_journal-766	180	12	cells	cell	NOUN
american_scientific_journal-766	180	13	.	.	PUNCT
american_scientific_journal-766	181	1	ns5b	ns5b	PROPN
american_scientific_journal-766	181	2	is	be	AUX
american_scientific_journal-766	181	3	one	one	NUM
american_scientific_journal-766	181	4	of	of	ADP
american_scientific_journal-766	181	5	the	the	DET
american_scientific_journal-766	181	6	non	non	ADJ
american_scientific_journal-766	181	7	-	-	ADJ
american_scientific_journal-766	181	8	structural	structural	ADJ
american_scientific_journal-766	181	9	proteins	protein	NOUN
american_scientific_journal-766	181	10	essential	essential	ADJ
american_scientific_journal-766	181	11	for	for	ADP
american_scientific_journal-766	181	12	viral	viral	ADJ
american_scientific_journal-766	181	13	rna	rna	NOUN
american_scientific_journal-766	181	14	replication	replication	NOUN
american_scientific_journal-766	181	15	,	,	PUNCT
american_scientific_journal-766	181	16	and	and	CCONJ
american_scientific_journal-766	181	17	has	have	AUX
american_scientific_journal-766	181	18	been	be	AUX
american_scientific_journal-766	181	19	found	find	VERB
american_scientific_journal-766	181	20	to	to	PART
american_scientific_journal-766	181	21	be	be	AUX
american_scientific_journal-766	181	22	a	a	DET
american_scientific_journal-766	181	23	valuable	valuable	ADJ
american_scientific_journal-766	181	24	target	target	NOUN
american_scientific_journal-766	181	25	for	for	ADP
american_scientific_journal-766	181	26	directly	directly	ADV
american_scientific_journal-766	181	27	acting	act	VERB
american_scientific_journal-766	181	28	antiviral	antiviral	ADJ
american_scientific_journal-766	181	29	agents	agent	NOUN
american_scientific_journal-766	181	30	(	(	PUNCT
american_scientific_journal-766	181	31	daas	daas	NOUN
american_scientific_journal-766	181	32	)	)	PUNCT
american_scientific_journal-766	182	1	[	[	X
american_scientific_journal-766	182	2	65	65	NUM
american_scientific_journal-766	182	3	]	]	PUNCT
american_scientific_journal-766	182	4	.	.	PUNCT
american_scientific_journal-766	183	1	prior	prior	ADV
american_scientific_journal-766	183	2	to	to	ADP
american_scientific_journal-766	183	3	the	the	DET
american_scientific_journal-766	183	4	discovery	discovery	NOUN
american_scientific_journal-766	183	5	of	of	ADP
american_scientific_journal-766	183	6	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	183	7	,	,	PUNCT
american_scientific_journal-766	183	8	a	a	DET
american_scientific_journal-766	183	9	variety	variety	NOUN
american_scientific_journal-766	183	10	of	of	ADP
american_scientific_journal-766	183	11	nucleoside	nucleoside	NOUN
american_scientific_journal-766	183	12	analogs	analog	NOUN
american_scientific_journal-766	183	13	had	have	AUX
american_scientific_journal-766	183	14	been	be	AUX
american_scientific_journal-766	183	15	examined	examine	VERB
american_scientific_journal-766	183	16	as	as	ADP
american_scientific_journal-766	183	17	anti	anti	ADJ
american_scientific_journal-766	183	18	-	-	ADJ
american_scientific_journal-766	183	19	hepatitis	hepatitis	ADJ
american_scientific_journal-766	183	20	c	c	NOUN
american_scientific_journal-766	183	21	treatments	treatment	NOUN
american_scientific_journal-766	183	22	,	,	PUNCT
american_scientific_journal-766	183	23	but	but	CCONJ
american_scientific_journal-766	183	24	these	these	PRON
american_scientific_journal-766	183	25	exhibited	exhibit	VERB
american_scientific_journal-766	183	26	relatively	relatively	ADV
american_scientific_journal-766	183	27	low	low	ADJ
american_scientific_journal-766	183	28	potency	potency	NOUN
american_scientific_journal-766	183	29	.	.	PUNCT
american_scientific_journal-766	184	1	this	this	DET
american_scientific_journal-766	184	2	low	low	ADJ
american_scientific_journal-766	184	3	potency	potency	NOUN
american_scientific_journal-766	184	4	arises	arise	VERB
american_scientific_journal-766	184	5	in	in	ADP
american_scientific_journal-766	184	6	part	part	NOUN
american_scientific_journal-766	184	7	because	because	SCONJ
american_scientific_journal-766	184	8	the	the	DET
american_scientific_journal-766	184	9	enzymatic	enzymatic	ADJ
american_scientific_journal-766	184	10	addition	addition	NOUN
american_scientific_journal-766	184	11	of	of	ADP
american_scientific_journal-766	184	12	the	the	DET
american_scientific_journal-766	184	13	first	first	ADJ
american_scientific_journal-766	184	14	of	of	ADP
american_scientific_journal-766	184	15	the	the	DET
american_scientific_journal-766	184	16	three	three	NUM
american_scientific_journal-766	184	17	phosphate	phosphate	ADJ
american_scientific_journal-766	184	18	groups	group	NOUN
american_scientific_journal-766	184	19	of	of	ADP
american_scientific_journal-766	184	20	the	the	DET
american_scientific_journal-766	184	21	triphosphate	triphosphate	NOUN
american_scientific_journal-766	184	22	is	be	AUX
american_scientific_journal-766	184	23	slow	slow	ADJ
american_scientific_journal-766	184	24	.	.	PUNCT
american_scientific_journal-766	185	1	the	the	DET
american_scientific_journal-766	185	2	design	design	NOUN
american_scientific_journal-766	185	3	of	of	ADP
american_scientific_journal-766	185	4	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	185	5	,	,	PUNCT
american_scientific_journal-766	185	6	based	base	VERB
american_scientific_journal-766	185	7	on	on	ADP
american_scientific_journal-766	185	8	the	the	DET
american_scientific_journal-766	185	9	protide	protide	NOUN
american_scientific_journal-766	185	10	approach	approach	NOUN
american_scientific_journal-766	185	11	,	,	PUNCT
american_scientific_journal-766	185	12	avoids	avoid	VERB
american_scientific_journal-766	185	13	this	this	DET
american_scientific_journal-766	185	14	slow	slow	ADJ
american_scientific_journal-766	185	15	step	step	NOUN
american_scientific_journal-766	185	16	by	by	ADP
american_scientific_journal-766	185	17	building	build	VERB
american_scientific_journal-766	185	18	the	the	DET
american_scientific_journal-766	185	19	first	first	ADJ
american_scientific_journal-766	185	20	phosphate	phosphate	ADJ
american_scientific_journal-766	185	21	group	group	NOUN
american_scientific_journal-766	185	22	into	into	ADP
american_scientific_journal-766	185	23	the	the	DET
american_scientific_journal-766	185	24	structure	structure	NOUN
american_scientific_journal-766	185	25	of	of	ADP
american_scientific_journal-766	185	26	the	the	DET
american_scientific_journal-766	185	27	drug	drug	NOUN
american_scientific_journal-766	185	28	during	during	ADP
american_scientific_journal-766	185	29	synthesis	synthesis	NOUN
american_scientific_journal-766	185	30	.	.	PUNCT
american_scientific_journal-766	186	1	additional	additional	ADJ
american_scientific_journal-766	186	2	groups	group	NOUN
american_scientific_journal-766	186	3	are	be	AUX
american_scientific_journal-766	186	4	attached	attach	VERB
american_scientific_journal-766	186	5	to	to	ADP
american_scientific_journal-766	186	6	the	the	DET
american_scientific_journal-766	186	7	phosphorus	phosphorus	NOUN
american_scientific_journal-766	186	8	to	to	PART
american_scientific_journal-766	186	9	temporarily	temporarily	ADV
american_scientific_journal-766	186	10	mask	mask	VERB
american_scientific_journal-766	186	11	the	the	DET
american_scientific_journal-766	186	12	two	two	NUM
american_scientific_journal-766	186	13	negative	negative	ADJ
american_scientific_journal-766	186	14	charges	charge	NOUN
american_scientific_journal-766	186	15	of	of	ADP
american_scientific_journal-766	186	16	the	the	DET
american_scientific_journal-766	186	17	phosphate	phosphate	ADJ
american_scientific_journal-766	186	18	group	group	NOUN
american_scientific_journal-766	186	19	,	,	PUNCT
american_scientific_journal-766	186	20	thereby	thereby	ADV
american_scientific_journal-766	186	21	facilitating	facilitate	VERB
american_scientific_journal-766	186	22	entry	entry	NOUN
american_scientific_journal-766	186	23	of	of	ADP
american_scientific_journal-766	186	24	the	the	DET
american_scientific_journal-766	186	25	drug	drug	NOUN
american_scientific_journal-766	186	26	into	into	ADP
american_scientific_journal-766	186	27	the	the	DET
american_scientific_journal-766	186	28	infected	infected	ADJ
american_scientific_journal-766	186	29	cell	cell	NOUN
american_scientific_journal-766	187	1	[	[	X
american_scientific_journal-766	187	2	66	66	NUM
american_scientific_journal-766	187	3	]	]	PUNCT
american_scientific_journal-766	187	4	.	.	PUNCT
american_scientific_journal-766	188	1	moreover	moreover	ADV
american_scientific_journal-766	188	2	,	,	PUNCT
american_scientific_journal-766	188	3	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	188	4	and	and	CCONJ
american_scientific_journal-766	188	5	other	other	ADJ
american_scientific_journal-766	188	6	nucleotide	nucleotide	ADJ
american_scientific_journal-766	188	7	inhibitors	inhibitor	NOUN
american_scientific_journal-766	188	8	of	of	ADP
american_scientific_journal-766	188	9	the	the	DET
american_scientific_journal-766	188	10	hcv	hcv	PROPN
american_scientific_journal-766	188	11	rna	rna	PROPN
american_scientific_journal-766	188	12	polymerase	polymerase	NOUN
american_scientific_journal-766	188	13	exhibit	exhibit	VERB
american_scientific_journal-766	188	14	a	a	DET
american_scientific_journal-766	188	15	very	very	ADV
american_scientific_journal-766	188	16	high	high	ADJ
american_scientific_journal-766	188	17	barrier	barrier	NOUN
american_scientific_journal-766	188	18	to	to	ADP
american_scientific_journal-766	188	19	resistance	resistance	NOUN
american_scientific_journal-766	188	20	development	development	NOUN
american_scientific_journal-766	188	21	.	.	PUNCT
american_scientific_journal-766	189	1	this	this	PRON
american_scientific_journal-766	189	2	is	be	AUX
american_scientific_journal-766	189	3	an	an	DET
american_scientific_journal-766	189	4	important	important	ADJ
american_scientific_journal-766	189	5	advantage	advantage	NOUN
american_scientific_journal-766	189	6	relative	relative	NOUN
american_scientific_journal-766	189	7	to	to	PART
american_scientific_journal-766	189	8	hcv	hcv	VERB
american_scientific_journal-766	189	9	drugs	drug	NOUN
american_scientific_journal-766	189	10	that	that	PRON
american_scientific_journal-766	189	11	target	target	VERB
american_scientific_journal-766	189	12	other	other	ADJ
american_scientific_journal-766	189	13	viral	viral	ADJ
american_scientific_journal-766	189	14	enzymes	enzyme	NOUN
american_scientific_journal-766	189	15	such	such	ADJ
american_scientific_journal-766	189	16	as	as	ADP
american_scientific_journal-766	189	17	the	the	DET
american_scientific_journal-766	189	18	protease	protease	NOUN
american_scientific_journal-766	189	19	,	,	PUNCT
american_scientific_journal-766	189	20	for	for	ADP
american_scientific_journal-766	189	21	which	which	PRON
american_scientific_journal-766	189	22	rapid	rapid	ADJ
american_scientific_journal-766	189	23	resistance	resistance	NOUN
american_scientific_journal-766	189	24	development	development	NOUN
american_scientific_journal-766	189	25	has	have	AUX
american_scientific_journal-766	189	26	proved	prove	VERB
american_scientific_journal-766	189	27	to	to	PART
american_scientific_journal-766	189	28	be	be	AUX
american_scientific_journal-766	189	29	an	an	DET
american_scientific_journal-766	189	30	important	important	ADJ
american_scientific_journal-766	189	31	cause	cause	NOUN
american_scientific_journal-766	189	32	of	of	ADP
american_scientific_journal-766	189	33	therapeutic	therapeutic	ADJ
american_scientific_journal-766	189	34	failure	failure	NOUN
american_scientific_journal-766	189	35	[	[	X
american_scientific_journal-766	189	36	67	67	NUM
american_scientific_journal-766	189	37	]	]	PUNCT
american_scientific_journal-766	189	38	.	.	PUNCT
american_scientific_journal-766	190	1	10	10	NUM
american_scientific_journal-766	190	2	http://en.wikipedia.org/wiki/protide	http://en.wikipedia.org/wiki/protide	PROPN
american_scientific_journal-766	190	3	http://en.wikipedia.org/wiki/prodrug	http://en.wikipedia.org/wiki/prodrug	PROPN
american_scientific_journal-766	191	1	http://en.wikipedia.org/wiki/ns5b	http://en.wikipedia.org/wiki/ns5b	PROPN
american_scientific_journal-766	192	1	http://en.wikipedia.org/wiki/sofosbuvir%23cite_note-25	http://en.wikipedia.org/wiki/sofosbuvir%23cite_note-25	INTJ
american_scientific_journal-766	192	2	http://en.wikipedia.org/wiki/protide	http://en.wikipedia.org/wiki/protide	PROPN
american_scientific_journal-766	192	3	american	american	PROPN
american_scientific_journal-766	192	4	scientific	scientific	ADJ
american_scientific_journal-766	192	5	research	research	NOUN
american_scientific_journal-766	192	6	journal	journal	NOUN
american_scientific_journal-766	192	7	for	for	ADP
american_scientific_journal-766	192	8	engineering	engineering	NOUN
american_scientific_journal-766	192	9	,	,	PUNCT
american_scientific_journal-766	192	10	technology	technology	NOUN
american_scientific_journal-766	192	11	,	,	PUNCT
american_scientific_journal-766	192	12	and	and	CCONJ
american_scientific_journal-766	192	13	sciences	science	NOUN
american_scientific_journal-766	192	14	(	(	PUNCT
american_scientific_journal-766	192	15	asrjets	asrjet	NOUN
american_scientific_journal-766	192	16	)	)	PUNCT
american_scientific_journal-766	192	17	(	(	PUNCT
american_scientific_journal-766	192	18	2015	2015	NUM
american_scientific_journal-766	192	19	)	)	PUNCT
american_scientific_journal-766	192	20	volume	volume	NOUN
american_scientific_journal-766	192	21	13	13	NUM
american_scientific_journal-766	192	22	,	,	PUNCT
american_scientific_journal-766	192	23	no	no	DET
american_scientific_journal-766	192	24	1	1	NUM
american_scientific_journal-766	192	25	,	,	PUNCT
american_scientific_journal-766	192	26	pp	pp	ADV
american_scientific_journal-766	192	27	1	1	NUM
american_scientific_journal-766	192	28	-	-	SYM
american_scientific_journal-766	192	29	23	23	NUM
american_scientific_journal-766	192	30	figure	figure	NOUN
american_scientific_journal-766	192	31	4	4	NUM
american_scientific_journal-766	192	32	;	;	PUNCT
american_scientific_journal-766	192	33	the	the	DET
american_scientific_journal-766	192	34	activation	activation	NOUN
american_scientific_journal-766	192	35	and	and	CCONJ
american_scientific_journal-766	192	36	metabolic	metabolic	NOUN
american_scientific_journal-766	192	37	pathway	pathway	NOUN
american_scientific_journal-766	192	38	of	of	ADP
american_scientific_journal-766	192	39	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	193	1	[	[	X
american_scientific_journal-766	193	2	69	69	NUM
american_scientific_journal-766	193	3	]	]	SYM
american_scientific_journal-766	193	4	.	.	PUNCT
american_scientific_journal-766	194	1	2.2.5	2.2.5	NUM
american_scientific_journal-766	194	2	.	.	PUNCT
american_scientific_journal-766	194	3	pharmacokinetics	pharmacokinetic	NOUN
american_scientific_journal-766	194	4	of	of	ADP
american_scientific_journal-766	194	5	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	194	6	the	the	DET
american_scientific_journal-766	194	7	main	main	ADJ
american_scientific_journal-766	194	8	goals	goal	NOUN
american_scientific_journal-766	194	9	in	in	ADP
american_scientific_journal-766	194	10	sof	sof	VERB
american_scientific_journal-766	194	11	development	development	NOUN
american_scientific_journal-766	194	12	for	for	ADP
american_scientific_journal-766	194	13	historically	historically	ADV
american_scientific_journal-766	194	14	“	"	PUNCT
american_scientific_journal-766	194	15	easy	easy	ADJ
american_scientific_journal-766	194	16	-	-	PUNCT
american_scientific_journal-766	194	17	to	to	ADP
american_scientific_journal-766	194	18	-	-	PUNCT
american_scientific_journal-766	194	19	treat	treat	VERB
american_scientific_journal-766	194	20	”	"	PUNCT
american_scientific_journal-766	194	21	genotypes	genotype	NOUN
american_scientific_journal-766	194	22	were	be	AUX
american_scientific_journal-766	194	23	to	to	PART
american_scientific_journal-766	194	24	shorten	shorten	VERB
american_scientific_journal-766	194	25	treatment	treatment	NOUN
american_scientific_journal-766	194	26	duration	duration	NOUN
american_scientific_journal-766	194	27	,	,	PUNCT
american_scientific_journal-766	194	28	but	but	CCONJ
american_scientific_journal-766	194	29	most	most	ADJ
american_scientific_journal-766	194	30	of	of	ADP
american_scientific_journal-766	194	31	all	all	PRON
american_scientific_journal-766	194	32	,	,	PUNCT
american_scientific_journal-766	194	33	to	to	PART
american_scientific_journal-766	194	34	improve	improve	VERB
american_scientific_journal-766	194	35	tolerability	tolerability	NOUN
american_scientific_journal-766	194	36	through	through	ADP
american_scientific_journal-766	194	37	an	an	DET
american_scientific_journal-766	194	38	ifn	ifn	NOUN
american_scientific_journal-766	194	39	-	-	PUNCT
american_scientific_journal-766	194	40	free	free	ADJ
american_scientific_journal-766	194	41	regimen	regiman	NOUN
american_scientific_journal-766	195	1	[	[	X
american_scientific_journal-766	195	2	68	68	NUM
american_scientific_journal-766	195	3	]	]	PUNCT
american_scientific_journal-766	195	4	)	)	PUNCT
american_scientific_journal-766	195	5	.	.	PUNCT
american_scientific_journal-766	196	1	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	196	2	has	have	VERB
american_scientific_journal-766	196	3	a	a	DET
american_scientific_journal-766	196	4	beneficial	beneficial	ADJ
american_scientific_journal-766	196	5	pharmacokinetic	pharmacokinetic	ADJ
american_scientific_journal-766	196	6	profile	profile	NOUN
american_scientific_journal-766	196	7	,	,	PUNCT
american_scientific_journal-766	196	8	being	be	AUX
american_scientific_journal-766	196	9	effective	effective	ADJ
american_scientific_journal-766	196	10	orally	orally	ADV
american_scientific_journal-766	196	11	as	as	ADP
american_scientific_journal-766	196	12	a	a	DET
american_scientific_journal-766	196	13	single	single	ADJ
american_scientific_journal-766	196	14	daily	daily	ADJ
american_scientific_journal-766	196	15	dose	dose	NOUN
american_scientific_journal-766	196	16	,	,	PUNCT
american_scientific_journal-766	196	17	and	and	CCONJ
american_scientific_journal-766	196	18	has	have	VERB
american_scientific_journal-766	196	19	rather	rather	ADV
american_scientific_journal-766	196	20	limited	limit	VERB
american_scientific_journal-766	196	21	potential	potential	NOUN
american_scientific_journal-766	196	22	for	for	ADP
american_scientific_journal-766	196	23	drugdrug	drugdrug	NOUN
american_scientific_journal-766	196	24	interactions	interaction	NOUN
american_scientific_journal-766	196	25	.	.	PUNCT
american_scientific_journal-766	197	1	however	however	ADV
american_scientific_journal-766	197	2	,	,	PUNCT
american_scientific_journal-766	197	3	some	some	DET
american_scientific_journal-766	197	4	issues	issue	NOUN
american_scientific_journal-766	197	5	remain	remain	VERB
american_scientific_journal-766	197	6	to	to	PART
american_scientific_journal-766	197	7	be	be	AUX
american_scientific_journal-766	197	8	elucidated	elucidate	VERB
american_scientific_journal-766	197	9	including	include	VERB
american_scientific_journal-766	197	10	the	the	DET
american_scientific_journal-766	197	11	reasons	reason	NOUN
american_scientific_journal-766	197	12	for	for	ADP
american_scientific_journal-766	197	13	hcv	hcv	NOUN
american_scientific_journal-766	197	14	relapse	relapse	NOUN
american_scientific_journal-766	197	15	after	after	ADP
american_scientific_journal-766	197	16	stopping	stop	VERB
american_scientific_journal-766	197	17	a	a	DET
american_scientific_journal-766	197	18	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	197	19	-	-	PUNCT
american_scientific_journal-766	197	20	based	base	VERB
american_scientific_journal-766	197	21	regimen	regiman	NOUN
american_scientific_journal-766	197	22	,	,	PUNCT
american_scientific_journal-766	197	23	the	the	DET
american_scientific_journal-766	197	24	possible	possible	ADJ
american_scientific_journal-766	197	25	impact	impact	NOUN
american_scientific_journal-766	197	26	of	of	ADP
american_scientific_journal-766	197	27	host	host	NOUN
american_scientific_journal-766	197	28	and	and	CCONJ
american_scientific_journal-766	197	29	viral	viral	ADJ
american_scientific_journal-766	197	30	factors	factor	NOUN
american_scientific_journal-766	197	31	associated	associate	VERB
american_scientific_journal-766	197	32	with	with	ADP
american_scientific_journal-766	197	33	hcv	hcv	NOUN
american_scientific_journal-766	197	34	eradication	eradication	NOUN
american_scientific_journal-766	197	35	,	,	PUNCT
american_scientific_journal-766	197	36	the	the	DET
american_scientific_journal-766	197	37	optimal	optimal	ADJ
american_scientific_journal-766	197	38	duration	duration	NOUN
american_scientific_journal-766	197	39	in	in	ADP
american_scientific_journal-766	197	40	difficult	difficult	ADJ
american_scientific_journal-766	197	41	-	-	PUNCT
american_scientific_journal-766	197	42	to	to	ADP
american_scientific_journal-766	197	43	-	-	PUNCT
american_scientific_journal-766	197	44	treat	treat	VERB
american_scientific_journal-766	197	45	population	population	NOUN
american_scientific_journal-766	197	46	,	,	PUNCT
american_scientific_journal-766	197	47	such	such	ADJ
american_scientific_journal-766	197	48	as	as	ADP
american_scientific_journal-766	197	49	prior	prior	ADJ
american_scientific_journal-766	197	50	non	non	NOUN
american_scientific_journal-766	197	51	-	-	NOUN
american_scientific_journal-766	197	52	responders	responder	NOUN
american_scientific_journal-766	197	53	with	with	ADP
american_scientific_journal-766	197	54	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	197	55	and	and	CCONJ
american_scientific_journal-766	197	56	its	its	PRON
american_scientific_journal-766	197	57	use	use	NOUN
american_scientific_journal-766	197	58	in	in	ADP
american_scientific_journal-766	197	59	patients	patient	NOUN
american_scientific_journal-766	197	60	with	with	ADP
american_scientific_journal-766	197	61	advanced	advanced	ADJ
american_scientific_journal-766	197	62	decompensated	decompensate	VERB
american_scientific_journal-766	197	63	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	197	64	[	[	X
american_scientific_journal-766	197	65	69	69	NUM
american_scientific_journal-766	197	66	]	]	PUNCT
american_scientific_journal-766	197	67	.	.	PUNCT
american_scientific_journal-766	198	1	sof	sof	PROPN
american_scientific_journal-766	198	2	is	be	AUX
american_scientific_journal-766	198	3	a	a	DET
american_scientific_journal-766	198	4	second	second	ADJ
american_scientific_journal-766	198	5	-	-	PUNCT
american_scientific_journal-766	198	6	generation	generation	NOUN
american_scientific_journal-766	198	7	ni	ni	NOUN
american_scientific_journal-766	198	8	,	,	PUNCT
american_scientific_journal-766	198	9	for	for	ADP
american_scientific_journal-766	198	10	treatment	treatment	NOUN
american_scientific_journal-766	198	11	of	of	ADP
american_scientific_journal-766	198	12	hcv	hcv	ADJ
american_scientific_journal-766	198	13	genotypes	genotype	NOUN
american_scientific_journal-766	198	14	2	2	NUM
american_scientific_journal-766	198	15	and	and	CCONJ
american_scientific_journal-766	198	16	3	3	NUM
american_scientific_journal-766	198	17	in	in	ADP
american_scientific_journal-766	198	18	combination	combination	NOUN
american_scientific_journal-766	198	19	with	with	ADP
american_scientific_journal-766	198	20	rbv	rbv	NOUN
american_scientific_journal-766	198	21	,	,	PUNCT
american_scientific_journal-766	198	22	and	and	CCONJ
american_scientific_journal-766	198	23	for	for	ADP
american_scientific_journal-766	198	24	genotypes	genotype	NOUN
american_scientific_journal-766	198	25	1	1	NUM
american_scientific_journal-766	198	26	and	and	CCONJ
american_scientific_journal-766	198	27	4	4	NUM
american_scientific_journal-766	198	28	in	in	ADP
american_scientific_journal-766	198	29	combination	combination	NOUN
american_scientific_journal-766	198	30	with	with	ADP
american_scientific_journal-766	198	31	pr	pr	NOUN
american_scientific_journal-766	198	32	,	,	PUNCT
american_scientific_journal-766	198	33	based	base	VERB
american_scientific_journal-766	198	34	on	on	ADP
american_scientific_journal-766	198	35	data	datum	NOUN
american_scientific_journal-766	198	36	from	from	ADP
american_scientific_journal-766	198	37	nearly	nearly	ADV
american_scientific_journal-766	198	38	3,000	3,000	NUM
american_scientific_journal-766	198	39	patients	patient	NOUN
american_scientific_journal-766	198	40	studied	study	VERB
american_scientific_journal-766	198	41	in	in	ADP
american_scientific_journal-766	198	42	phase	phase	NOUN
american_scientific_journal-766	198	43	ii	ii	PROPN
american_scientific_journal-766	198	44	and	and	CCONJ
american_scientific_journal-766	198	45	iii	iii	NUM
american_scientific_journal-766	198	46	trials	trial	NOUN
american_scientific_journal-766	198	47	[	[	X
american_scientific_journal-766	198	48	70	70	NUM
american_scientific_journal-766	198	49	]	]	PUNCT
american_scientific_journal-766	198	50	.	.	PUNCT
american_scientific_journal-766	199	1	it	it	PRON
american_scientific_journal-766	199	2	enters	enter	VERB
american_scientific_journal-766	199	3	the	the	DET
american_scientific_journal-766	199	4	hepatocytes	hepatocyte	NOUN
american_scientific_journal-766	199	5	as	as	ADP
american_scientific_journal-766	199	6	a	a	DET
american_scientific_journal-766	199	7	prodrug	prodrug	NOUN
american_scientific_journal-766	199	8	of	of	ADP
american_scientific_journal-766	199	9	uridine	uridine	NOUN
american_scientific_journal-766	199	10	monophosphate	monophosphate	NOUN
american_scientific_journal-766	199	11	and	and	CCONJ
american_scientific_journal-766	199	12	is	be	AUX
american_scientific_journal-766	199	13	phosphorylated	phosphorylate	VERB
american_scientific_journal-766	199	14	within	within	ADP
american_scientific_journal-766	199	15	the	the	DET
american_scientific_journal-766	199	16	cells	cell	NOUN
american_scientific_journal-766	199	17	to	to	ADP
american_scientific_journal-766	199	18	active	active	ADJ
american_scientific_journal-766	199	19	triphosphate	triphosphate	NOUN
american_scientific_journal-766	199	20	form	form	NOUN
american_scientific_journal-766	199	21	.	.	PUNCT
american_scientific_journal-766	200	1	dephosphorylation	dephosphorylation	NOUN
american_scientific_journal-766	200	2	of	of	ADP
american_scientific_journal-766	200	3	the	the	DET
american_scientific_journal-766	200	4	active	active	ADJ
american_scientific_journal-766	200	5	molecule	molecule	NOUN
american_scientific_journal-766	200	6	results	result	NOUN
american_scientific_journal-766	200	7	in	in	ADP
american_scientific_journal-766	200	8	the	the	DET
american_scientific_journal-766	200	9	formation	formation	NOUN
american_scientific_journal-766	200	10	of	of	ADP
american_scientific_journal-766	200	11	the	the	DET
american_scientific_journal-766	200	12	metabolite	metabolite	NOUN
american_scientific_journal-766	200	13	gs-331007	gs-331007	VERB
american_scientific_journal-766	200	14	,	,	PUNCT
american_scientific_journal-766	200	15	which	which	PRON
american_scientific_journal-766	200	16	lacks	lack	VERB
american_scientific_journal-766	200	17	anti	anti	ADJ
american_scientific_journal-766	200	18	-	-	ADJ
american_scientific_journal-766	200	19	hcv	hcv	ADJ
american_scientific_journal-766	200	20	activity	activity	NOUN
american_scientific_journal-766	200	21	;	;	PUNCT
american_scientific_journal-766	201	1	gs331007	gs331007	NOUN
american_scientific_journal-766	201	2	is	be	AUX
american_scientific_journal-766	201	3	the	the	DET
american_scientific_journal-766	201	4	main	main	ADJ
american_scientific_journal-766	201	5	circulating	circulate	VERB
american_scientific_journal-766	201	6	metabolite	metabolite	NOUN
american_scientific_journal-766	201	7	of	of	ADP
american_scientific_journal-766	201	8	sof	sof	PROPN
american_scientific_journal-766	201	9	and	and	CCONJ
american_scientific_journal-766	201	10	undergoes	undergo	VERB
american_scientific_journal-766	201	11	renal	renal	ADJ
american_scientific_journal-766	201	12	elimination	elimination	NOUN
american_scientific_journal-766	201	13	.	.	PUNCT
american_scientific_journal-766	202	1	the	the	DET
american_scientific_journal-766	202	2	median	median	ADJ
american_scientific_journal-766	202	3	half	half	ADJ
american_scientific_journal-766	202	4	-	-	PUNCT
american_scientific_journal-766	202	5	lives	life	NOUN
american_scientific_journal-766	202	6	of	of	ADP
american_scientific_journal-766	202	7	sof	sof	NOUN
american_scientific_journal-766	202	8	and	and	CCONJ
american_scientific_journal-766	202	9	gs-331007	gs-331007	NOUN
american_scientific_journal-766	202	10	are	be	AUX
american_scientific_journal-766	202	11	0.4	0.4	NUM
american_scientific_journal-766	202	12	and	and	CCONJ
american_scientific_journal-766	202	13	27	27	NUM
american_scientific_journal-766	202	14	hours	hour	NOUN
american_scientific_journal-766	202	15	,	,	PUNCT
american_scientific_journal-766	202	16	respectively	respectively	ADV
american_scientific_journal-766	202	17	.	.	PUNCT
american_scientific_journal-766	203	1	population	population	NOUN
american_scientific_journal-766	203	2	pharmacokinetic	pharmacokinetic	ADJ
american_scientific_journal-766	203	3	(	(	PUNCT
american_scientific_journal-766	203	4	pk	pk	NOUN
american_scientific_journal-766	203	5	)	)	PUNCT
american_scientific_journal-766	203	6	models	model	NOUN
american_scientific_journal-766	203	7	developed	develop	VERB
american_scientific_journal-766	203	8	for	for	ADP
american_scientific_journal-766	203	9	gs-331007	gs-331007	NOUN
american_scientific_journal-766	203	10	and	and	CCONJ
american_scientific_journal-766	203	11	sof	sof	PROPN
american_scientific_journal-766	203	12	revealed	reveal	VERB
american_scientific_journal-766	203	13	that	that	SCONJ
american_scientific_journal-766	203	14	demographic	demographic	ADJ
american_scientific_journal-766	203	15	variables	variable	NOUN
american_scientific_journal-766	203	16	such	such	ADJ
american_scientific_journal-766	203	17	as	as	ADP
american_scientific_journal-766	203	18	age	age	NOUN
american_scientific_journal-766	203	19	,	,	PUNCT
american_scientific_journal-766	203	20	sex	sex	NOUN
american_scientific_journal-766	203	21	,	,	PUNCT
american_scientific_journal-766	203	22	bmi	bmi	NOUN
american_scientific_journal-766	203	23	,	,	PUNCT
american_scientific_journal-766	203	24	race	race	NOUN
american_scientific_journal-766	203	25	,	,	PUNCT
american_scientific_journal-766	203	26	common	common	ADJ
american_scientific_journal-766	203	27	concomitant	concomitant	ADJ
american_scientific_journal-766	203	28	medications	medication	NOUN
american_scientific_journal-766	203	29	,	,	PUNCT
american_scientific_journal-766	203	30	and	and	CCONJ
american_scientific_journal-766	203	31	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	203	32	did	do	AUX
american_scientific_journal-766	203	33	not	not	PART
american_scientific_journal-766	203	34	influence	influence	VERB
american_scientific_journal-766	203	35	gs-331007	gs-331007	VERB
american_scientific_journal-766	203	36	or	or	CCONJ
american_scientific_journal-766	203	37	sof	sof	VERB
american_scientific_journal-766	203	38	exposure	exposure	NOUN
american_scientific_journal-766	203	39	(	(	PUNCT
american_scientific_journal-766	203	40	fig	fig	NOUN
american_scientific_journal-766	203	41	.	.	PUNCT
american_scientific_journal-766	204	1	4	4	X
american_scientific_journal-766	204	2	)	)	PUNCT
american_scientific_journal-766	205	1	[	[	X
american_scientific_journal-766	205	2	71	71	NUM
american_scientific_journal-766	205	3	]	]	SYM
american_scientific_journal-766	205	4	.	.	PUNCT
american_scientific_journal-766	206	1	2.2.5.1	2.2.5.1	NUM
american_scientific_journal-766	206	2	.	.	PUNCT
american_scientific_journal-766	207	1	efficacy	efficacy	NOUN
american_scientific_journal-766	207	2	and	and	CCONJ
american_scientific_journal-766	207	3	safety	safety	NOUN
american_scientific_journal-766	208	1	;	;	PUNCT
american_scientific_journal-766	208	2	the	the	DET
american_scientific_journal-766	208	3	efficacy	efficacy	NOUN
american_scientific_journal-766	208	4	and	and	CCONJ
american_scientific_journal-766	208	5	safety	safety	NOUN
american_scientific_journal-766	208	6	of	of	ADP
american_scientific_journal-766	208	7	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	208	8	in	in	ADP
american_scientific_journal-766	208	9	patients	patient	NOUN
american_scientific_journal-766	208	10	with	with	ADP
american_scientific_journal-766	208	11	different	different	ADJ
american_scientific_journal-766	208	12	hcv	hcv	NOUN
american_scientific_journal-766	208	13	genotypes	genotype	NOUN
american_scientific_journal-766	208	14	and	and	CCONJ
american_scientific_journal-766	208	15	with	with	ADP
american_scientific_journal-766	208	16	various	various	ADJ
american_scientific_journal-766	208	17	combinations	combination	NOUN
american_scientific_journal-766	208	18	of	of	ADP
american_scientific_journal-766	208	19	drugs	drug	NOUN
american_scientific_journal-766	208	20	have	have	AUX
american_scientific_journal-766	208	21	been	be	AUX
american_scientific_journal-766	208	22	tested	test	VERB
american_scientific_journal-766	208	23	in	in	ADP
american_scientific_journal-766	208	24	numerous	numerous	ADJ
american_scientific_journal-766	208	25	clinical	clinical	ADJ
american_scientific_journal-766	208	26	trials	trial	NOUN
american_scientific_journal-766	208	27	.	.	PUNCT
american_scientific_journal-766	209	1	a	a	DET
american_scientific_journal-766	209	2	dose	dose	NOUN
american_scientific_journal-766	209	3	of	of	ADP
american_scientific_journal-766	209	4	400	400	NUM
american_scientific_journal-766	209	5	mg	mg	NOUN
american_scientific_journal-766	209	6	of	of	ADP
american_scientific_journal-766	209	7	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	209	8	has	have	AUX
american_scientific_journal-766	209	9	been	be	AUX
american_scientific_journal-766	209	10	found	find	VERB
american_scientific_journal-766	209	11	to	to	PART
american_scientific_journal-766	209	12	be	be	AUX
american_scientific_journal-766	209	13	most	most	ADV
american_scientific_journal-766	209	14	effective	effective	ADJ
american_scientific_journal-766	209	15	,	,	PUNCT
american_scientific_journal-766	209	16	with	with	ADP
american_scientific_journal-766	209	17	treatment	treatment	NOUN
american_scientific_journal-766	209	18	durations	duration	NOUN
american_scientific_journal-766	209	19	ranging	range	VERB
american_scientific_journal-766	209	20	from	from	ADP
american_scientific_journal-766	209	21	12	12	NUM
american_scientific_journal-766	209	22	to	to	PART
american_scientific_journal-766	209	23	24	24	NUM
american_scientific_journal-766	209	24	weeks	week	NOUN
american_scientific_journal-766	209	25	,	,	PUNCT
american_scientific_journal-766	209	26	in	in	ADP
american_scientific_journal-766	209	27	various	various	ADJ
american_scientific_journal-766	209	28	combinations	combination	NOUN
american_scientific_journal-766	209	29	of	of	ADP
american_scientific_journal-766	209	30	peg	peg	NOUN
american_scientific_journal-766	209	31	-	-	PUNCT
american_scientific_journal-766	209	32	ifn	ifn	PROPN
american_scientific_journal-766	209	33	and	and	CCONJ
american_scientific_journal-766	209	34	ribavirin	ribavirin	NOUN
american_scientific_journal-766	209	35	.	.	PUNCT
american_scientific_journal-766	210	1	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	210	2	has	have	AUX
american_scientific_journal-766	210	3	been	be	AUX
american_scientific_journal-766	210	4	studied	study	VERB
american_scientific_journal-766	210	5	in	in	ADP
american_scientific_journal-766	210	6	different	different	ADJ
american_scientific_journal-766	210	7	combinations	combination	NOUN
american_scientific_journal-766	210	8	[	[	X
american_scientific_journal-766	210	9	72	72	NUM
american_scientific_journal-766	210	10	]	]	PUNCT
american_scientific_journal-766	210	11	.	.	PUNCT
american_scientific_journal-766	211	1	the	the	DET
american_scientific_journal-766	211	2	value	value	NOUN
american_scientific_journal-766	211	3	of	of	ADP
american_scientific_journal-766	211	4	adding	add	VERB
american_scientific_journal-766	211	5	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	211	6	to	to	ADP
american_scientific_journal-766	211	7	the	the	DET
american_scientific_journal-766	211	8	combination	combination	NOUN
american_scientific_journal-766	211	9	of	of	ADP
american_scientific_journal-766	211	10	peg	peg	NOUN
american_scientific_journal-766	211	11	-	-	PUNCT
american_scientific_journal-766	211	12	ifnα	ifnα	NOUN
american_scientific_journal-766	211	13	in	in	ADP
american_scientific_journal-766	211	14	genotype	genotype	NOUN
american_scientific_journal-766	211	15	1	1	NUM
american_scientific_journal-766	211	16	patients	patient	NOUN
american_scientific_journal-766	211	17	was	be	AUX
american_scientific_journal-766	211	18	first	first	ADV
american_scientific_journal-766	211	19	addressed	address	VERB
american_scientific_journal-766	211	20	in	in	ADP
american_scientific_journal-766	211	21	two	two	NUM
american_scientific_journal-766	211	22	phase	phase	NOUN
american_scientific_journal-766	211	23	ii	ii	NOUN
american_scientific_journal-766	211	24	trials	trial	NOUN
american_scientific_journal-766	211	25	(	(	PUNCT
american_scientific_journal-766	211	26	proton	proton	NOUN
american_scientific_journal-766	211	27	and	and	CCONJ
american_scientific_journal-766	211	28	11	11	NUM
american_scientific_journal-766	211	29	american	american	ADJ
american_scientific_journal-766	211	30	scientific	scientific	ADJ
american_scientific_journal-766	211	31	research	research	NOUN
american_scientific_journal-766	211	32	journal	journal	NOUN
american_scientific_journal-766	211	33	for	for	ADP
american_scientific_journal-766	211	34	engineering	engineering	NOUN
american_scientific_journal-766	211	35	,	,	PUNCT
american_scientific_journal-766	211	36	technology	technology	NOUN
american_scientific_journal-766	211	37	,	,	PUNCT
american_scientific_journal-766	211	38	and	and	CCONJ
american_scientific_journal-766	211	39	sciences	science	NOUN
american_scientific_journal-766	211	40	(	(	PUNCT
american_scientific_journal-766	211	41	asrjets	asrjet	NOUN
american_scientific_journal-766	211	42	)	)	PUNCT
american_scientific_journal-766	211	43	(	(	PUNCT
american_scientific_journal-766	211	44	2015	2015	NUM
american_scientific_journal-766	211	45	)	)	PUNCT
american_scientific_journal-766	211	46	volume	volume	NOUN
american_scientific_journal-766	211	47	13	13	NUM
american_scientific_journal-766	211	48	,	,	PUNCT
american_scientific_journal-766	211	49	no	no	DET
american_scientific_journal-766	211	50	1	1	NUM
american_scientific_journal-766	211	51	,	,	PUNCT
american_scientific_journal-766	211	52	pp	pp	ADV
american_scientific_journal-766	211	53	1	1	NUM
american_scientific_journal-766	211	54	-	-	SYM
american_scientific_journal-766	211	55	23	23	NUM
american_scientific_journal-766	211	56	atomic	atomic	NOUN
american_scientific_journal-766	211	57	)	)	PUNCT
american_scientific_journal-766	211	58	(	(	PUNCT
american_scientific_journal-766	211	59	table	table	NOUN
american_scientific_journal-766	211	60	2	2	NUM
american_scientific_journal-766	211	61	)	)	PUNCT
american_scientific_journal-766	211	62	.	.	PUNCT
american_scientific_journal-766	212	1	the	the	DET
american_scientific_journal-766	212	2	first	first	ADJ
american_scientific_journal-766	212	3	study	study	NOUN
american_scientific_journal-766	212	4	proton	proton	NOUN
american_scientific_journal-766	212	5	was	be	AUX
american_scientific_journal-766	212	6	a	a	DET
american_scientific_journal-766	212	7	double	double	ADJ
american_scientific_journal-766	212	8	-	-	PUNCT
american_scientific_journal-766	212	9	blind	blind	ADJ
american_scientific_journal-766	212	10	,	,	PUNCT
american_scientific_journal-766	212	11	randomized	randomize	VERB
american_scientific_journal-766	212	12	,	,	PUNCT
american_scientific_journal-766	212	13	placebo	placebo	NOUN
american_scientific_journal-766	212	14	-	-	PUNCT
american_scientific_journal-766	212	15	controlled	control	VERB
american_scientific_journal-766	212	16	,	,	PUNCT
american_scientific_journal-766	212	17	dose	dose	NOUN
american_scientific_journal-766	212	18	-	-	PUNCT
american_scientific_journal-766	212	19	ranging	range	VERB
american_scientific_journal-766	212	20	phase	phase	NOUN
american_scientific_journal-766	212	21	ii	ii	NOUN
american_scientific_journal-766	212	22	study	study	NOUN
american_scientific_journal-766	212	23	that	that	PRON
american_scientific_journal-766	212	24	demonstrated	demonstrate	VERB
american_scientific_journal-766	212	25	that	that	SCONJ
american_scientific_journal-766	212	26	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	212	27	was	be	AUX
american_scientific_journal-766	212	28	highly	highly	ADV
american_scientific_journal-766	212	29	effective	effective	ADJ
american_scientific_journal-766	212	30	against	against	ADP
american_scientific_journal-766	212	31	genotypes	genotype	NOUN
american_scientific_journal-766	212	32	1	1	NUM
american_scientific_journal-766	212	33	,	,	PUNCT
american_scientific_journal-766	212	34	2	2	NUM
american_scientific_journal-766	212	35	and	and	CCONJ
american_scientific_journal-766	212	36	3	3	NUM
american_scientific_journal-766	212	37	hcv	hcv	NOUN
american_scientific_journal-766	212	38	when	when	SCONJ
american_scientific_journal-766	212	39	used	use	VERB
american_scientific_journal-766	212	40	in	in	ADP
american_scientific_journal-766	212	41	combination	combination	NOUN
american_scientific_journal-766	212	42	with	with	ADP
american_scientific_journal-766	212	43	peg	peg	NOUN
american_scientific_journal-766	212	44	-	-	PUNCT
american_scientific_journal-766	212	45	interferon	interferon	NOUN
american_scientific_journal-766	212	46	and	and	CCONJ
american_scientific_journal-766	212	47	ribavirin	ribavirin	NOUN
american_scientific_journal-766	212	48	as	as	ADP
american_scientific_journal-766	212	49	12	12	NUM
american_scientific_journal-766	212	50	-	-	PUNCT
american_scientific_journal-766	212	51	week	week	NOUN
american_scientific_journal-766	212	52	triple	triple	ADJ
american_scientific_journal-766	212	53	therapy	therapy	NOUN
american_scientific_journal-766	212	54	,	,	PUNCT
american_scientific_journal-766	212	55	followed	follow	VERB
american_scientific_journal-766	212	56	by	by	ADP
american_scientific_journal-766	212	57	additional	additional	ADJ
american_scientific_journal-766	212	58	peg	peg	NOUN
american_scientific_journal-766	212	59	-	-	PUNCT
american_scientific_journal-766	212	60	interferon	interferon	NOUN
american_scientific_journal-766	212	61	and	and	CCONJ
american_scientific_journal-766	212	62	ribavirin	ribavirin	NOUN
american_scientific_journal-766	212	63	in	in	ADP
american_scientific_journal-766	212	64	the	the	DET
american_scientific_journal-766	212	65	genotype	genotype	NOUN
american_scientific_journal-766	212	66	1	1	NUM
american_scientific_journal-766	212	67	patients	patient	NOUN
american_scientific_journal-766	212	68	,	,	PUNCT
american_scientific_journal-766	212	69	results	result	VERB
american_scientific_journal-766	212	70	greater	great	ADJ
american_scientific_journal-766	212	71	than	than	ADP
american_scientific_journal-766	212	72	90	90	NUM
american_scientific_journal-766	212	73	%	%	NOUN
american_scientific_journal-766	212	74	in	in	ADP
american_scientific_journal-766	212	75	all	all	DET
american_scientific_journal-766	212	76	sofosbuvir	sofosbuvir	NOUN
american_scientific_journal-766	212	77	-	-	PUNCT
american_scientific_journal-766	212	78	containing	contain	VERB
american_scientific_journal-766	212	79	arms	arm	NOUN
american_scientific_journal-766	212	80	of	of	ADP
american_scientific_journal-766	212	81	the	the	DET
american_scientific_journal-766	212	82	study	study	NOUN
american_scientific_journal-766	212	83	[	[	X
american_scientific_journal-766	212	84	73	73	NUM
american_scientific_journal-766	212	85	]	]	PUNCT
american_scientific_journal-766	212	86	.	.	PUNCT
american_scientific_journal-766	213	1	the	the	DET
american_scientific_journal-766	213	2	other	other	ADJ
american_scientific_journal-766	213	3	trial	trial	NOUN
american_scientific_journal-766	213	4	(	(	PUNCT
american_scientific_journal-766	213	5	atomic	atomic	NOUN
american_scientific_journal-766	213	6	)	)	PUNCT
american_scientific_journal-766	213	7	evaluated	evaluate	VERB
american_scientific_journal-766	213	8	the	the	DET
american_scientific_journal-766	213	9	role	role	NOUN
american_scientific_journal-766	213	10	of	of	ADP
american_scientific_journal-766	213	11	maintenance	maintenance	NOUN
american_scientific_journal-766	213	12	therapy	therapy	NOUN
american_scientific_journal-766	213	13	after	after	ADP
american_scientific_journal-766	213	14	the	the	DET
american_scientific_journal-766	213	15	initial	initial	ADJ
american_scientific_journal-766	213	16	12	12	NUM
american_scientific_journal-766	213	17	week	week	NOUN
american_scientific_journal-766	213	18	response	response	NOUN
american_scientific_journal-766	213	19	.	.	PUNCT
american_scientific_journal-766	214	1	the	the	DET
american_scientific_journal-766	214	2	atomic	atomic	ADJ
american_scientific_journal-766	214	3	study	study	NOUN
american_scientific_journal-766	214	4	explored	explore	VERB
american_scientific_journal-766	214	5	shorter	short	ADJ
american_scientific_journal-766	214	6	treatment	treatment	NOUN
american_scientific_journal-766	214	7	durations	duration	NOUN
american_scientific_journal-766	214	8	of	of	ADP
american_scientific_journal-766	214	9	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	214	10	-	-	PUNCT
american_scientific_journal-766	214	11	based	base	VERB
american_scientific_journal-766	214	12	triple	triple	ADJ
american_scientific_journal-766	214	13	therapy	therapy	NOUN
american_scientific_journal-766	214	14	,	,	PUNCT
american_scientific_journal-766	214	15	and	and	CCONJ
american_scientific_journal-766	214	16	randomized	randomize	VERB
american_scientific_journal-766	214	17	316	316	NUM
american_scientific_journal-766	214	18	treatment	treatment	NOUN
american_scientific_journal-766	214	19	-	-	PUNCT
american_scientific_journal-766	214	20	naïve	naïve	ADJ
american_scientific_journal-766	214	21	patients	patient	NOUN
american_scientific_journal-766	214	22	with	with	ADP
american_scientific_journal-766	214	23	genotype	genotype	NOUN
american_scientific_journal-766	214	24	1	1	NUM
american_scientific_journal-766	214	25	hcv	hcv	NOUN
american_scientific_journal-766	214	26	into	into	ADP
american_scientific_journal-766	214	27	three	three	NUM
american_scientific_journal-766	214	28	treatment	treatment	NOUN
american_scientific_journal-766	214	29	arms	arm	NOUN
american_scientific_journal-766	214	30	that	that	PRON
american_scientific_journal-766	214	31	included	include	VERB
american_scientific_journal-766	214	32	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	214	33	400	400	NUM
american_scientific_journal-766	214	34	mg	mg	PROPN
american_scientific_journal-766	214	35	plus	plus	CCONJ
american_scientific_journal-766	214	36	peg	peg	NOUN
american_scientific_journal-766	214	37	-	-	PUNCT
american_scientific_journal-766	214	38	interferon	interferon	NOUN
american_scientific_journal-766	214	39	and	and	CCONJ
american_scientific_journal-766	214	40	ribavirin	ribavirin	NOUN
american_scientific_journal-766	214	41	therapy	therapy	NOUN
american_scientific_journal-766	214	42	of	of	ADP
american_scientific_journal-766	214	43	12	12	NUM
american_scientific_journal-766	214	44	or	or	CCONJ
american_scientific_journal-766	214	45	24	24	NUM
american_scientific_journal-766	214	46	weeks	week	NOUN
american_scientific_journal-766	214	47	duration	duration	NOUN
american_scientific_journal-766	214	48	,	,	PUNCT
american_scientific_journal-766	214	49	and	and	CCONJ
american_scientific_journal-766	214	50	one	one	NUM
american_scientific_journal-766	214	51	arm	arm	NOUN
american_scientific_journal-766	214	52	who	who	PRON
american_scientific_journal-766	214	53	received	receive	VERB
american_scientific_journal-766	214	54	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	214	55	triple	triple	ADJ
american_scientific_journal-766	214	56	therapy	therapy	NOUN
american_scientific_journal-766	214	57	for	for	ADP
american_scientific_journal-766	214	58	12	12	NUM
american_scientific_journal-766	214	59	weeks	week	NOUN
american_scientific_journal-766	214	60	,	,	PUNCT
american_scientific_journal-766	214	61	and	and	CCONJ
american_scientific_journal-766	214	62	then	then	ADV
american_scientific_journal-766	214	63	subjects	subject	NOUN
american_scientific_journal-766	214	64	were	be	AUX
american_scientific_journal-766	214	65	randomized	randomize	VERB
american_scientific_journal-766	214	66	to	to	PART
american_scientific_journal-766	214	67	receive	receive	VERB
american_scientific_journal-766	214	68	a	a	DET
american_scientific_journal-766	214	69	further	further	ADJ
american_scientific_journal-766	214	70	12	12	NUM
american_scientific_journal-766	214	71	weeks	week	NOUN
american_scientific_journal-766	214	72	of	of	ADP
american_scientific_journal-766	214	73	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	214	74	alone	alone	ADJ
american_scientific_journal-766	214	75	or	or	CCONJ
american_scientific_journal-766	214	76	with	with	ADP
american_scientific_journal-766	214	77	ribavirin	ribavirin	NOUN
american_scientific_journal-766	214	78	.	.	PUNCT
american_scientific_journal-766	215	1	svr	svr	PROPN
american_scientific_journal-766	215	2	rates	rate	NOUN
american_scientific_journal-766	215	3	remained	remain	VERB
american_scientific_journal-766	215	4	greater	great	ADJ
american_scientific_journal-766	215	5	than	than	ADP
american_scientific_journal-766	215	6	90	90	NUM
american_scientific_journal-766	215	7	%	%	NOUN
american_scientific_journal-766	215	8	in	in	ADP
american_scientific_journal-766	215	9	all	all	DET
american_scientific_journal-766	215	10	arms	arm	NOUN
american_scientific_journal-766	215	11	of	of	ADP
american_scientific_journal-766	215	12	this	this	DET
american_scientific_journal-766	215	13	study	study	NOUN
american_scientific_journal-766	215	14	,	,	PUNCT
american_scientific_journal-766	215	15	with	with	ADP
american_scientific_journal-766	215	16	minimal	minimal	ADJ
american_scientific_journal-766	215	17	differences	difference	NOUN
american_scientific_journal-766	215	18	in	in	ADP
american_scientific_journal-766	215	19	svr	svr	PROPN
american_scientific_journal-766	215	20	seen	see	VERB
american_scientific_journal-766	215	21	in	in	ADP
american_scientific_journal-766	215	22	patients	patient	NOUN
american_scientific_journal-766	215	23	with	with	ADP
american_scientific_journal-766	215	24	factors	factor	NOUN
american_scientific_journal-766	215	25	traditionally	traditionally	ADV
american_scientific_journal-766	215	26	associated	associate	VERB
american_scientific_journal-766	215	27	with	with	ADP
american_scientific_journal-766	215	28	reduced	reduced	ADJ
american_scientific_journal-766	215	29	response	response	NOUN
american_scientific_journal-766	215	30	to	to	ADP
american_scientific_journal-766	215	31	interferon	interferon	NOUN
american_scientific_journal-766	215	32	-	-	PUNCT
american_scientific_journal-766	215	33	based	base	VERB
american_scientific_journal-766	215	34	therapy	therapy	NOUN
american_scientific_journal-766	215	35	such	such	ADJ
american_scientific_journal-766	215	36	as	as	ADP
american_scientific_journal-766	215	37	high	high	ADJ
american_scientific_journal-766	215	38	baseline	baseline	ADJ
american_scientific_journal-766	215	39	viral	viral	ADJ
american_scientific_journal-766	215	40	load	load	NOUN
american_scientific_journal-766	215	41	,	,	PUNCT
american_scientific_journal-766	215	42	patients	patient	NOUN
american_scientific_journal-766	215	43	with	with	ADP
american_scientific_journal-766	215	44	non	non	ADJ
american_scientific_journal-766	215	45	-	-	ADJ
american_scientific_journal-766	215	46	cc	cc	ADJ
american_scientific_journal-766	215	47	il28b	il28b	NOUN
american_scientific_journal-766	215	48	genotypes	genotype	NOUN
american_scientific_journal-766	215	49	or	or	CCONJ
american_scientific_journal-766	215	50	bridging	bridge	VERB
american_scientific_journal-766	215	51	fibrosis	fibrosis	NOUN
american_scientific_journal-766	215	52	on	on	ADP
american_scientific_journal-766	215	53	liver	liver	NOUN
american_scientific_journal-766	215	54	biopsy	biopsy	NOUN
american_scientific_journal-766	215	55	[	[	X
american_scientific_journal-766	215	56	74	74	NUM
american_scientific_journal-766	215	57	]	]	PUNCT
american_scientific_journal-766	215	58	.	.	PUNCT
american_scientific_journal-766	216	1	following	follow	VERB
american_scientific_journal-766	216	2	on	on	ADP
american_scientific_journal-766	216	3	from	from	ADP
american_scientific_journal-766	216	4	proton	proton	NOUN
american_scientific_journal-766	216	5	and	and	CCONJ
american_scientific_journal-766	216	6	atomic	atomic	NOUN
american_scientific_journal-766	216	7	,	,	PUNCT
american_scientific_journal-766	216	8	the	the	DET
american_scientific_journal-766	216	9	electron	electron	NOUN
american_scientific_journal-766	216	10	study	study	NOUN
american_scientific_journal-766	216	11	evaluated	evaluate	VERB
american_scientific_journal-766	216	12	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	216	13	in	in	ADP
american_scientific_journal-766	216	14	interferon	interferon	ADJ
american_scientific_journal-766	216	15	-	-	PUNCT
american_scientific_journal-766	216	16	sparing	spare	VERB
american_scientific_journal-766	216	17	and	and	CCONJ
american_scientific_journal-766	216	18	interferon	interferon	ADJ
american_scientific_journal-766	216	19	-	-	PUNCT
american_scientific_journal-766	216	20	free	free	ADJ
american_scientific_journal-766	216	21	regimens	regimen	NOUN
american_scientific_journal-766	216	22	for	for	ADP
american_scientific_journal-766	216	23	the	the	DET
american_scientific_journal-766	216	24	treatment	treatment	NOUN
american_scientific_journal-766	216	25	of	of	ADP
american_scientific_journal-766	216	26	hcv	hcv	ADJ
american_scientific_journal-766	216	27	infection	infection	NOUN
american_scientific_journal-766	216	28	in	in	ADP
american_scientific_journal-766	216	29	noncirrhotic	noncirrhotic	ADJ
american_scientific_journal-766	216	30	patients	patient	NOUN
american_scientific_journal-766	216	31	.	.	PUNCT
american_scientific_journal-766	217	1	the	the	DET
american_scientific_journal-766	217	2	electron	electron	NOUN
american_scientific_journal-766	217	3	trial	trial	NOUN
american_scientific_journal-766	217	4	was	be	AUX
american_scientific_journal-766	217	5	the	the	DET
american_scientific_journal-766	217	6	first	first	ADJ
american_scientific_journal-766	217	7	phase	phase	NOUN
american_scientific_journal-766	217	8	ii	ii	PROPN
american_scientific_journal-766	217	9	study	study	NOUN
american_scientific_journal-766	217	10	in	in	ADP
american_scientific_journal-766	217	11	treatment	treatment	NOUN
american_scientific_journal-766	217	12	-	-	PUNCT
american_scientific_journal-766	217	13	naïve	naïve	ADJ
american_scientific_journal-766	217	14	patients	patient	NOUN
american_scientific_journal-766	217	15	to	to	PART
american_scientific_journal-766	217	16	explore	explore	VERB
american_scientific_journal-766	217	17	an	an	DET
american_scientific_journal-766	217	18	ifn	ifn	NOUN
american_scientific_journal-766	217	19	-	-	PUNCT
american_scientific_journal-766	217	20	free	free	ADJ
american_scientific_journal-766	217	21	arm	arm	NOUN
american_scientific_journal-766	217	22	of	of	ADP
american_scientific_journal-766	217	23	sof	sof	PROPN
american_scientific_journal-766	217	24	/	/	SYM
american_scientific_journal-766	217	25	rbv	rbv	NOUN
american_scientific_journal-766	217	26	for	for	ADP
american_scientific_journal-766	217	27	12	12	NUM
american_scientific_journal-766	217	28	weeks	week	NOUN
american_scientific_journal-766	217	29	compared	compare	VERB
american_scientific_journal-766	217	30	to	to	ADP
american_scientific_journal-766	217	31	three	three	NUM
american_scientific_journal-766	217	32	arms	arm	NOUN
american_scientific_journal-766	217	33	of	of	ADP
american_scientific_journal-766	217	34	variable	variable	ADJ
american_scientific_journal-766	217	35	pegifn	pegifn	NOUN
american_scientific_journal-766	217	36	duration	duration	NOUN
american_scientific_journal-766	217	37	(	(	PUNCT
american_scientific_journal-766	217	38	4/8/12	4/8/12	PROPN
american_scientific_journal-766	217	39	weeks	week	NOUN
american_scientific_journal-766	217	40	)	)	PUNCT
american_scientific_journal-766	217	41	,	,	PUNCT
american_scientific_journal-766	217	42	with	with	ADP
american_scientific_journal-766	217	43	100	100	NUM
american_scientific_journal-766	217	44	%	%	NOUN
american_scientific_journal-766	217	45	svr	svr	NOUN
american_scientific_journal-766	217	46	in	in	ADP
american_scientific_journal-766	217	47	both	both	CCONJ
american_scientific_journal-766	217	48	the	the	DET
american_scientific_journal-766	217	49	pegifn	pegifn	NOUN
american_scientific_journal-766	217	50	-	-	PUNCT
american_scientific_journal-766	217	51	based	base	VERB
american_scientific_journal-766	217	52	and	and	CCONJ
american_scientific_journal-766	217	53	ifn	ifn	NOUN
american_scientific_journal-766	217	54	-	-	PUNCT
american_scientific_journal-766	217	55	free	free	ADJ
american_scientific_journal-766	217	56	arms	arm	NOUN
american_scientific_journal-766	217	57	[	[	X
american_scientific_journal-766	217	58	75	75	NUM
american_scientific_journal-766	217	59	]	]	PUNCT
american_scientific_journal-766	217	60	.	.	PUNCT
american_scientific_journal-766	218	1	the	the	DET
american_scientific_journal-766	218	2	electron	electron	NOUN
american_scientific_journal-766	218	3	trial	trial	NOUN
american_scientific_journal-766	218	4	also	also	ADV
american_scientific_journal-766	218	5	demonstrated	demonstrate	VERB
american_scientific_journal-766	218	6	that	that	SCONJ
american_scientific_journal-766	218	7	the	the	DET
american_scientific_journal-766	218	8	key	key	ADJ
american_scientific_journal-766	218	9	role	role	NOUN
american_scientific_journal-766	218	10	of	of	ADP
american_scientific_journal-766	218	11	rbv	rbv	NOUN
american_scientific_journal-766	218	12	could	could	AUX
american_scientific_journal-766	218	13	not	not	PART
american_scientific_journal-766	218	14	be	be	AUX
american_scientific_journal-766	218	15	superseded	supersede	VERB
american_scientific_journal-766	218	16	,	,	PUNCT
american_scientific_journal-766	218	17	as	as	SCONJ
american_scientific_journal-766	218	18	a	a	DET
american_scientific_journal-766	218	19	sof	sof	NOUN
american_scientific_journal-766	218	20	monotherapy	monotherapy	NOUN
american_scientific_journal-766	218	21	12	12	NUM
american_scientific_journal-766	218	22	-	-	PUNCT
american_scientific_journal-766	218	23	week	week	NOUN
american_scientific_journal-766	218	24	arm	arm	NOUN
american_scientific_journal-766	218	25	reported	report	VERB
american_scientific_journal-766	218	26	svr	svr	PROPN
american_scientific_journal-766	218	27	of	of	ADP
american_scientific_journal-766	218	28	60	60	NUM
american_scientific_journal-766	218	29	%	%	NOUN
american_scientific_journal-766	218	30	due	due	ADP
american_scientific_journal-766	218	31	to	to	ADP
american_scientific_journal-766	218	32	a	a	DET
american_scientific_journal-766	218	33	40	40	NUM
american_scientific_journal-766	218	34	%	%	NOUN
american_scientific_journal-766	218	35	virological	virological	ADJ
american_scientific_journal-766	218	36	relapse	relapse	NOUN
american_scientific_journal-766	218	37	rate	rate	NOUN
american_scientific_journal-766	218	38	.	.	PUNCT
american_scientific_journal-766	219	1	based	base	VERB
american_scientific_journal-766	219	2	on	on	ADP
american_scientific_journal-766	219	3	these	these	DET
american_scientific_journal-766	219	4	results	result	NOUN
american_scientific_journal-766	219	5	,	,	PUNCT
american_scientific_journal-766	219	6	the	the	DET
american_scientific_journal-766	219	7	sof	sof	PROPN
american_scientific_journal-766	219	8	/	/	SYM
american_scientific_journal-766	219	9	rbv	rbv	NOUN
american_scientific_journal-766	219	10	combination	combination	NOUN
american_scientific_journal-766	219	11	administered	administer	VERB
american_scientific_journal-766	219	12	for	for	ADP
american_scientific_journal-766	219	13	12	12	NUM
american_scientific_journal-766	219	14	weeks	week	NOUN
american_scientific_journal-766	219	15	was	be	AUX
american_scientific_journal-766	219	16	chosen	choose	VERB
american_scientific_journal-766	219	17	to	to	PART
american_scientific_journal-766	219	18	be	be	AUX
american_scientific_journal-766	219	19	further	far	ADV
american_scientific_journal-766	219	20	evaluated	evaluate	VERB
american_scientific_journal-766	219	21	in	in	ADP
american_scientific_journal-766	219	22	phase	phase	NOUN
american_scientific_journal-766	219	23	iii	iii	NUM
american_scientific_journal-766	219	24	trials	trial	NOUN
american_scientific_journal-766	219	25	.	.	PUNCT
american_scientific_journal-766	220	1	studies	study	NOUN
american_scientific_journal-766	220	2	that	that	PRON
american_scientific_journal-766	220	3	tested	test	VERB
american_scientific_journal-766	220	4	for	for	ADP
american_scientific_journal-766	220	5	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	220	6	in	in	ADP
american_scientific_journal-766	220	7	genotype	genotype	NOUN
american_scientific_journal-766	220	8	1	1	NUM
american_scientific_journal-766	220	9	included	include	VERB
american_scientific_journal-766	220	10	quantum	quantum	NOUN
american_scientific_journal-766	220	11	and	and	CCONJ
american_scientific_journal-766	220	12	electron	electron	NOUN
american_scientific_journal-766	220	13	studies	study	NOUN
american_scientific_journal-766	220	14	.	.	PUNCT
american_scientific_journal-766	221	1	fifty	fifty	NUM
american_scientific_journal-766	221	2	naïve	naïve	ADJ
american_scientific_journal-766	221	3	patients	patient	NOUN
american_scientific_journal-766	221	4	were	be	AUX
american_scientific_journal-766	221	5	treated	treat	VERB
american_scientific_journal-766	221	6	with	with	ADP
american_scientific_journal-766	221	7	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	221	8	and	and	CCONJ
american_scientific_journal-766	221	9	ribavirin	ribavirin	NOUN
american_scientific_journal-766	221	10	for	for	ADP
american_scientific_journal-766	221	11	12	12	NUM
american_scientific_journal-766	221	12	weeks	week	NOUN
american_scientific_journal-766	221	13	.	.	PUNCT
american_scientific_journal-766	222	1	svr12	svr12	ADJ
american_scientific_journal-766	222	2	rates	rate	NOUN
american_scientific_journal-766	222	3	were	be	AUX
american_scientific_journal-766	222	4	56	56	NUM
american_scientific_journal-766	222	5	%	%	NOUN
american_scientific_journal-766	222	6	and	and	CCONJ
american_scientific_journal-766	222	7	88	88	NUM
american_scientific_journal-766	222	8	%	%	NOUN
american_scientific_journal-766	222	9	respectively	respectively	ADV
american_scientific_journal-766	222	10	[	[	X
american_scientific_journal-766	222	11	79	79	NUM
american_scientific_journal-766	222	12	]	]	PUNCT
american_scientific_journal-766	222	13	.	.	PUNCT
american_scientific_journal-766	223	1	neutrino	neutrino	NOUN
american_scientific_journal-766	223	2	was	be	AUX
american_scientific_journal-766	223	3	the	the	DET
american_scientific_journal-766	223	4	first	first	ADJ
american_scientific_journal-766	223	5	sof	sof	NOUN
american_scientific_journal-766	223	6	phase	phase	NOUN
american_scientific_journal-766	223	7	iii	iii	NUM
american_scientific_journal-766	223	8	trial	trial	NOUN
american_scientific_journal-766	223	9	in	in	ADP
american_scientific_journal-766	223	10	naïve	naïve	ADJ
american_scientific_journal-766	223	11	patients	patient	NOUN
american_scientific_journal-766	223	12	with	with	ADP
american_scientific_journal-766	223	13	the	the	DET
american_scientific_journal-766	223	14	aim	aim	NOUN
american_scientific_journal-766	223	15	to	to	PART
american_scientific_journal-766	223	16	evaluate	evaluate	VERB
american_scientific_journal-766	223	17	the	the	DET
american_scientific_journal-766	223	18	safety	safety	NOUN
american_scientific_journal-766	223	19	and	and	CCONJ
american_scientific_journal-766	223	20	efficacy	efficacy	NOUN
american_scientific_journal-766	223	21	of	of	ADP
american_scientific_journal-766	223	22	the	the	DET
american_scientific_journal-766	223	23	combination	combination	NOUN
american_scientific_journal-766	223	24	regimen	regimen	NOUN
american_scientific_journal-766	223	25	sof	sof	VERB
american_scientific_journal-766	223	26	/	/	SYM
american_scientific_journal-766	223	27	pegifn	pegifn	NOUN
american_scientific_journal-766	223	28	/	/	SYM
american_scientific_journal-766	223	29	rbv	rbv	NOUN
american_scientific_journal-766	223	30	for	for	ADP
american_scientific_journal-766	223	31	12	12	NUM
american_scientific_journal-766	223	32	weeks	week	NOUN
american_scientific_journal-766	223	33	.	.	PUNCT
american_scientific_journal-766	224	1	the	the	DET
american_scientific_journal-766	224	2	neutrino	neutrino	NOUN
american_scientific_journal-766	224	3	trial	trial	NOUN
american_scientific_journal-766	224	4	included	include	VERB
american_scientific_journal-766	224	5	28	28	NUM
american_scientific_journal-766	224	6	chc	chc	NOUN
american_scientific_journal-766	224	7	patients	patient	NOUN
american_scientific_journal-766	224	8	with	with	ADP
american_scientific_journal-766	224	9	genotype	genotype	NOUN
american_scientific_journal-766	224	10	4	4	NUM
american_scientific_journal-766	224	11	and	and	CCONJ
american_scientific_journal-766	224	12	7	7	NUM
american_scientific_journal-766	224	13	patients	patient	NOUN
american_scientific_journal-766	224	14	with	with	ADP
american_scientific_journal-766	224	15	genotype	genotype	NOUN
american_scientific_journal-766	224	16	5	5	NUM
american_scientific_journal-766	224	17	or	or	CCONJ
american_scientific_journal-766	224	18	6	6	NUM
american_scientific_journal-766	224	19	who	who	PRON
american_scientific_journal-766	224	20	were	be	AUX
american_scientific_journal-766	224	21	treated	treat	VERB
american_scientific_journal-766	224	22	with	with	ADP
american_scientific_journal-766	224	23	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	224	24	plus	plus	CCONJ
american_scientific_journal-766	224	25	pegifn	pegifn	NOUN
american_scientific_journal-766	224	26	and	and	CCONJ
american_scientific_journal-766	224	27	weightbased	weightbase	VERB
american_scientific_journal-766	224	28	rbv	rbv	NOUN
american_scientific_journal-766	224	29	for	for	ADP
american_scientific_journal-766	224	30	12	12	NUM
american_scientific_journal-766	224	31	weeks	week	NOUN
american_scientific_journal-766	224	32	.	.	PUNCT
american_scientific_journal-766	225	1	the	the	DET
american_scientific_journal-766	225	2	svr	svr	PROPN
american_scientific_journal-766	225	3	rates	rate	NOUN
american_scientific_journal-766	225	4	were	be	AUX
american_scientific_journal-766	225	5	96	96	NUM
american_scientific_journal-766	225	6	%	%	NOUN
american_scientific_journal-766	225	7	in	in	ADP
american_scientific_journal-766	225	8	genotype	genotype	NOUN
american_scientific_journal-766	225	9	4	4	NUM
american_scientific_journal-766	225	10	and	and	CCONJ
american_scientific_journal-766	225	11	100	100	NUM
american_scientific_journal-766	225	12	%	%	NOUN
american_scientific_journal-766	225	13	in	in	ADP
american_scientific_journal-766	225	14	genotype	genotype	NOUN
american_scientific_journal-766	225	15	5	5	NUM
american_scientific_journal-766	225	16	-	-	SYM
american_scientific_journal-766	225	17	6	6	NUM
american_scientific_journal-766	225	18	patients	patient	NOUN
american_scientific_journal-766	225	19	[	[	X
american_scientific_journal-766	225	20	71].the	71].the	DET
american_scientific_journal-766	225	21	combination	combination	NOUN
american_scientific_journal-766	225	22	of	of	ADP
american_scientific_journal-766	225	23	sof	sof	NOUN
american_scientific_journal-766	225	24	/	/	SYM
american_scientific_journal-766	225	25	pegifn	pegifn	NOUN
american_scientific_journal-766	225	26	/	/	SYM
american_scientific_journal-766	225	27	rbv	rbv	NOUN
american_scientific_journal-766	225	28	for	for	ADP
american_scientific_journal-766	225	29	12	12	NUM
american_scientific_journal-766	225	30	weeks	week	NOUN
american_scientific_journal-766	225	31	demonstrated	demonstrate	VERB
american_scientific_journal-766	225	32	high	high	ADJ
american_scientific_journal-766	225	33	rates	rate	NOUN
american_scientific_journal-766	225	34	of	of	ADP
american_scientific_journal-766	225	35	on	on	ADP
american_scientific_journal-766	225	36	-	-	PUNCT
american_scientific_journal-766	225	37	treatment	treatment	NOUN
american_scientific_journal-766	225	38	response	response	NOUN
american_scientific_journal-766	225	39	,	,	PUNCT
american_scientific_journal-766	225	40	with	with	ADP
american_scientific_journal-766	225	41	91	91	NUM
american_scientific_journal-766	225	42	%	%	NOUN
american_scientific_journal-766	225	43	of	of	ADP
american_scientific_journal-766	225	44	patients	patient	NOUN
american_scientific_journal-766	225	45	achieving	achieve	VERB
american_scientific_journal-766	225	46	hcv	hcv	PROPN
american_scientific_journal-766	225	47	-	-	PUNCT
american_scientific_journal-766	225	48	rna	rna	NOUN
american_scientific_journal-766	225	49	undetectability	undetectability	NOUN
american_scientific_journal-766	225	50	at	at	ADP
american_scientific_journal-766	225	51	week	week	NOUN
american_scientific_journal-766	225	52	2	2	NUM
american_scientific_journal-766	225	53	and	and	CCONJ
american_scientific_journal-766	225	54	99	99	NUM
american_scientific_journal-766	225	55	%	%	NOUN
american_scientific_journal-766	225	56	at	at	ADP
american_scientific_journal-766	225	57	week	week	NOUN
american_scientific_journal-766	225	58	4	4	NUM
american_scientific_journal-766	225	59	,	,	PUNCT
american_scientific_journal-766	225	60	which	which	PRON
american_scientific_journal-766	225	61	resulted	result	VERB
american_scientific_journal-766	225	62	in	in	ADP
american_scientific_journal-766	225	63	an	an	DET
american_scientific_journal-766	225	64	overall	overall	ADJ
american_scientific_journal-766	225	65	svr	svr	NOUN
american_scientific_journal-766	225	66	rate	rate	NOUN
american_scientific_journal-766	225	67	of	of	ADP
american_scientific_journal-766	225	68	90	90	NUM
american_scientific_journal-766	225	69	%	%	NOUN
american_scientific_journal-766	225	70	.	.	PUNCT
american_scientific_journal-766	226	1	concerning	concern	VERB
american_scientific_journal-766	226	2	safety	safety	NOUN
american_scientific_journal-766	226	3	profile	profile	NOUN
american_scientific_journal-766	226	4	,	,	PUNCT
american_scientific_journal-766	226	5	the	the	DET
american_scientific_journal-766	226	6	most	most	ADV
american_scientific_journal-766	226	7	common	common	ADJ
american_scientific_journal-766	226	8	side	side	NOUN
american_scientific_journal-766	226	9	effects	effect	NOUN
american_scientific_journal-766	226	10	reported	report	VERB
american_scientific_journal-766	226	11	were	be	AUX
american_scientific_journal-766	226	12	fatigue	fatigue	NOUN
american_scientific_journal-766	226	13	(	(	PUNCT
american_scientific_journal-766	226	14	59	59	NUM
american_scientific_journal-766	226	15	%	%	NOUN
american_scientific_journal-766	226	16	)	)	PUNCT
american_scientific_journal-766	226	17	,	,	PUNCT
american_scientific_journal-766	226	18	headache	headache	NOUN
american_scientific_journal-766	226	19	(	(	PUNCT
american_scientific_journal-766	226	20	36	36	NUM
american_scientific_journal-766	226	21	%	%	NOUN
american_scientific_journal-766	226	22	)	)	PUNCT
american_scientific_journal-766	226	23	,	,	PUNCT
american_scientific_journal-766	226	24	nausea	nausea	NOUN
american_scientific_journal-766	226	25	(	(	PUNCT
american_scientific_journal-766	226	26	34	34	NUM
american_scientific_journal-766	226	27	%	%	NOUN
american_scientific_journal-766	226	28	)	)	PUNCT
american_scientific_journal-766	226	29	,	,	PUNCT
american_scientific_journal-766	226	30	and	and	CCONJ
american_scientific_journal-766	226	31	insomnia	insomnia	NOUN
american_scientific_journal-766	226	32	(	(	PUNCT
american_scientific_journal-766	226	33	25	25	NUM
american_scientific_journal-766	226	34	%	%	NOUN
american_scientific_journal-766	226	35	)	)	PUNCT
american_scientific_journal-766	226	36	,	,	PUNCT
american_scientific_journal-766	226	37	which	which	PRON
american_scientific_journal-766	226	38	are	be	AUX
american_scientific_journal-766	226	39	mainly	mainly	ADV
american_scientific_journal-766	226	40	consistent	consistent	ADJ
american_scientific_journal-766	226	41	with	with	ADP
american_scientific_journal-766	226	42	rbv	rbv	NOUN
american_scientific_journal-766	226	43	or	or	CCONJ
american_scientific_journal-766	226	44	pegifn	pegifn	NOUN
american_scientific_journal-766	226	45	safety	safety	NOUN
american_scientific_journal-766	226	46	profiles	profile	NOUN
american_scientific_journal-766	226	47	.	.	PUNCT
american_scientific_journal-766	227	1	anemia	anemia	NOUN
american_scientific_journal-766	227	2	with	with	ADP
american_scientific_journal-766	227	3	hb	hb	PROPN
american_scientific_journal-766	227	4	<	<	PROPN
american_scientific_journal-766	227	5	10	10	NUM
american_scientific_journal-766	227	6	g	g	NOUN
american_scientific_journal-766	227	7	/	/	SYM
american_scientific_journal-766	227	8	dl	dl	PROPN
american_scientific_journal-766	227	9	was	be	AUX
american_scientific_journal-766	227	10	observed	observe	VERB
american_scientific_journal-766	227	11	in	in	ADP
american_scientific_journal-766	227	12	23	23	NUM
american_scientific_journal-766	227	13	%	%	NOUN
american_scientific_journal-766	227	14	,	,	PUNCT
american_scientific_journal-766	227	15	while	while	SCONJ
american_scientific_journal-766	227	16	only	only	ADV
american_scientific_journal-766	227	17	2	2	NUM
american_scientific_journal-766	227	18	%	%	NOUN
american_scientific_journal-766	227	19	of	of	ADP
american_scientific_journal-766	227	20	patients	patient	NOUN
american_scientific_journal-766	227	21	had	have	VERB
american_scientific_journal-766	227	22	hb	hb	PROPN
american_scientific_journal-766	227	23	<	<	X
american_scientific_journal-766	227	24	8.5	8.5	NUM
american_scientific_journal-766	227	25	g	g	NOUN
american_scientific_journal-766	227	26	/	/	SYM
american_scientific_journal-766	227	27	dl	dl	PROPN
american_scientific_journal-766	228	1	[	[	X
american_scientific_journal-766	228	2	77	77	NUM
american_scientific_journal-766	228	3	]	]	PUNCT
american_scientific_journal-766	228	4	.	.	PUNCT
american_scientific_journal-766	229	1	in	in	ADP
american_scientific_journal-766	229	2	a	a	DET
american_scientific_journal-766	229	3	phase	phase	NOUN
american_scientific_journal-766	229	4	iii	iii	NUM
american_scientific_journal-766	229	5	non	non	ADJ
american_scientific_journal-766	229	6	-	-	ADJ
american_scientific_journal-766	229	7	inferiority	inferiority	ADJ
american_scientific_journal-766	229	8	trial	trial	NOUN
american_scientific_journal-766	229	9	study	study	NOUN
american_scientific_journal-766	229	10	named	name	VERB
american_scientific_journal-766	229	11	fission	fission	NOUN
american_scientific_journal-766	229	12	,	,	PUNCT
american_scientific_journal-766	229	13	nearly	nearly	ADV
american_scientific_journal-766	229	14	500	500	NUM
american_scientific_journal-766	229	15	genotype	genotype	NOUN
american_scientific_journal-766	229	16	2	2	NUM
american_scientific_journal-766	229	17	or	or	CCONJ
american_scientific_journal-766	229	18	3	3	NUM
american_scientific_journal-766	229	19	naïve	naïve	ADJ
american_scientific_journal-766	229	20	chc	chc	NOUN
american_scientific_journal-766	229	21	patients	patient	NOUN
american_scientific_journal-766	229	22	were	be	AUX
american_scientific_journal-766	229	23	randomized	randomize	VERB
american_scientific_journal-766	229	24	to	to	PART
american_scientific_journal-766	229	25	receive	receive	VERB
american_scientific_journal-766	229	26	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	229	27	plus	plus	CCONJ
american_scientific_journal-766	229	28	weight	weight	NOUN
american_scientific_journal-766	229	29	-	-	PUNCT
american_scientific_journal-766	229	30	based	base	VERB
american_scientific_journal-766	229	31	rbv	rbv	NOUN
american_scientific_journal-766	229	32	for	for	ADP
american_scientific_journal-766	229	33	12	12	NUM
american_scientific_journal-766	229	34	weeks	week	NOUN
american_scientific_journal-766	229	35	(	(	PUNCT
american_scientific_journal-766	229	36	n=256	n=256	NOUN
american_scientific_journal-766	229	37	)	)	PUNCT
american_scientific_journal-766	229	38	or	or	CCONJ
american_scientific_journal-766	229	39	soc	soc	NOUN
american_scientific_journal-766	229	40	,	,	PUNCT
american_scientific_journal-766	229	41	i.e.	i.e.	X
american_scientific_journal-766	229	42	pegifn	pegifn	NOUN
american_scientific_journal-766	229	43	plus	plus	CCONJ
american_scientific_journal-766	229	44	rbv	rbv	PROPN
american_scientific_journal-766	229	45	(	(	PUNCT
american_scientific_journal-766	229	46	800	800	NUM
american_scientific_journal-766	229	47	mg	mg	NOUN
american_scientific_journal-766	229	48	daily	daily	ADV
american_scientific_journal-766	229	49	)	)	PUNCT
american_scientific_journal-766	229	50	for	for	ADP
american_scientific_journal-766	229	51	24	24	NUM
american_scientific_journal-766	229	52	weeks	week	NOUN
american_scientific_journal-766	229	53	(	(	PUNCT
american_scientific_journal-766	229	54	n=243	n=243	NUM
american_scientific_journal-766	229	55	)	)	PUNCT
american_scientific_journal-766	229	56	.	.	PUNCT
american_scientific_journal-766	230	1	approximately	approximately	ADV
american_scientific_journal-766	230	2	20	20	NUM
american_scientific_journal-766	230	3	%	%	NOUN
american_scientific_journal-766	230	4	had	have	VERB
american_scientific_journal-766	230	5	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	230	6	and	and	CCONJ
american_scientific_journal-766	230	7	29	29	NUM
american_scientific_journal-766	230	8	%	%	NOUN
american_scientific_journal-766	230	9	had	have	VERB
american_scientific_journal-766	230	10	interleukin-28b	interleukin-28b	PROPN
american_scientific_journal-766	230	11	(	(	PUNCT
american_scientific_journal-766	230	12	il28b	il28b	PROPN
american_scientific_journal-766	230	13	)	)	PUNCT
american_scientific_journal-766	230	14	cc	cc	NOUN
american_scientific_journal-766	230	15	genotype	genotype	NOUN
american_scientific_journal-766	230	16	.	.	PUNCT
american_scientific_journal-766	231	1	the	the	DET
american_scientific_journal-766	231	2	combination	combination	NOUN
american_scientific_journal-766	231	3	of	of	ADP
american_scientific_journal-766	231	4	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	231	5	plus	plus	CCONJ
american_scientific_journal-766	231	6	rbv	rbv	ADV
american_scientific_journal-766	231	7	achieved	achieve	VERB
american_scientific_journal-766	231	8	svr	svr	PROPN
american_scientific_journal-766	231	9	in	in	ADP
american_scientific_journal-766	231	10	97	97	NUM
american_scientific_journal-766	231	11	%	%	NOUN
american_scientific_journal-766	231	12	of	of	ADP
american_scientific_journal-766	231	13	genotype	genotype	NOUN
american_scientific_journal-766	231	14	2	2	NUM
american_scientific_journal-766	231	15	(	(	PUNCT
american_scientific_journal-766	231	16	78	78	NUM
american_scientific_journal-766	231	17	%	%	NOUN
american_scientific_journal-766	231	18	with	with	ADP
american_scientific_journal-766	231	19	soc	soc	NOUN
american_scientific_journal-766	231	20	)	)	PUNCT
american_scientific_journal-766	231	21	12	12	NUM
american_scientific_journal-766	231	22	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23t0005	http://www.sciencedirect.com/science/article/pii/s2090123214001374%23t0005	VERB
american_scientific_journal-766	231	23	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3968818/%23bibr19-1756283x13515825	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3968818/%23bibr19-1756283x13515825	PROPN
american_scientific_journal-766	232	1	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3968818/%23bibr14-1756283x13515825	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3968818/%23bibr14-1756283x13515825	NUM
american_scientific_journal-766	232	2	american	american	ADJ
american_scientific_journal-766	232	3	scientific	scientific	ADJ
american_scientific_journal-766	232	4	research	research	NOUN
american_scientific_journal-766	232	5	journal	journal	NOUN
american_scientific_journal-766	232	6	for	for	ADP
american_scientific_journal-766	232	7	engineering	engineering	NOUN
american_scientific_journal-766	232	8	,	,	PUNCT
american_scientific_journal-766	232	9	technology	technology	NOUN
american_scientific_journal-766	232	10	,	,	PUNCT
american_scientific_journal-766	232	11	and	and	CCONJ
american_scientific_journal-766	232	12	sciences	science	NOUN
american_scientific_journal-766	232	13	(	(	PUNCT
american_scientific_journal-766	232	14	asrjets	asrjet	NOUN
american_scientific_journal-766	232	15	)	)	PUNCT
american_scientific_journal-766	232	16	(	(	PUNCT
american_scientific_journal-766	232	17	2015	2015	NUM
american_scientific_journal-766	232	18	)	)	PUNCT
american_scientific_journal-766	232	19	volume	volume	NOUN
american_scientific_journal-766	232	20	13	13	NUM
american_scientific_journal-766	232	21	,	,	PUNCT
american_scientific_journal-766	232	22	no	no	DET
american_scientific_journal-766	232	23	1	1	NUM
american_scientific_journal-766	232	24	,	,	PUNCT
american_scientific_journal-766	232	25	pp	pp	ADV
american_scientific_journal-766	232	26	1	1	NUM
american_scientific_journal-766	232	27	-	-	SYM
american_scientific_journal-766	232	28	23	23	NUM
american_scientific_journal-766	232	29	and	and	CCONJ
american_scientific_journal-766	232	30	56	56	NUM
american_scientific_journal-766	232	31	%	%	NOUN
american_scientific_journal-766	232	32	of	of	ADP
american_scientific_journal-766	232	33	genotype	genotype	NOUN
american_scientific_journal-766	232	34	3	3	NUM
american_scientific_journal-766	232	35	patients	patient	NOUN
american_scientific_journal-766	232	36	(	(	PUNCT
american_scientific_journal-766	232	37	63	63	NUM
american_scientific_journal-766	232	38	%	%	NOUN
american_scientific_journal-766	232	39	with	with	ADP
american_scientific_journal-766	232	40	soc	soc	NOUN
american_scientific_journal-766	232	41	)	)	PUNCT
american_scientific_journal-766	232	42	.	.	PUNCT
american_scientific_journal-766	233	1	svr	svr	PROPN
american_scientific_journal-766	233	2	rates	rate	NOUN
american_scientific_journal-766	233	3	under	under	ADP
american_scientific_journal-766	233	4	sofosbuvir	sofosbuvir	NOUN
american_scientific_journal-766	233	5	and	and	CCONJ
american_scientific_journal-766	233	6	rbv	rbv	ADV
american_scientific_journal-766	233	7	were	be	AUX
american_scientific_journal-766	233	8	lower	low	ADJ
american_scientific_journal-766	233	9	in	in	ADP
american_scientific_journal-766	233	10	patients	patient	NOUN
american_scientific_journal-766	233	11	with	with	ADP
american_scientific_journal-766	233	12	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	233	13	(	(	PUNCT
american_scientific_journal-766	233	14	genotype	genotype	NOUN
american_scientific_journal-766	233	15	2	2	NUM
american_scientific_journal-766	233	16	:	:	SYM
american_scientific_journal-766	233	17	91	91	NUM
american_scientific_journal-766	233	18	%	%	NOUN
american_scientific_journal-766	233	19	,	,	PUNCT
american_scientific_journal-766	233	20	genotype	genotype	NOUN
american_scientific_journal-766	233	21	3	3	NUM
american_scientific_journal-766	233	22	:	:	SYM
american_scientific_journal-766	233	23	34	34	NUM
american_scientific_journal-766	233	24	%	%	NOUN
american_scientific_journal-766	233	25	)	)	PUNCT
american_scientific_journal-766	233	26	compared	compare	VERB
american_scientific_journal-766	233	27	to	to	ADP
american_scientific_journal-766	233	28	those	those	PRON
american_scientific_journal-766	233	29	without	without	ADP
american_scientific_journal-766	233	30	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	233	31	(	(	PUNCT
american_scientific_journal-766	233	32	genotype	genotype	NOUN
american_scientific_journal-766	233	33	2	2	NUM
american_scientific_journal-766	233	34	:	:	SYM
american_scientific_journal-766	233	35	98	98	NUM
american_scientific_journal-766	233	36	%	%	NOUN
american_scientific_journal-766	233	37	,	,	PUNCT
american_scientific_journal-766	233	38	genotype	genotype	NOUN
american_scientific_journal-766	233	39	3	3	NUM
american_scientific_journal-766	233	40	:	:	SYM
american_scientific_journal-766	233	41	61	61	NUM
american_scientific_journal-766	233	42	%	%	NOUN
american_scientific_journal-766	233	43	)	)	PUNCT
american_scientific_journal-766	233	44	without	without	ADP
american_scientific_journal-766	233	45	significant	significant	ADJ
american_scientific_journal-766	233	46	difference	difference	NOUN
american_scientific_journal-766	233	47	from	from	ADP
american_scientific_journal-766	233	48	the	the	DET
american_scientific_journal-766	233	49	svr	svr	PROPN
american_scientific_journal-766	233	50	achieved	achieve	VERB
american_scientific_journal-766	233	51	by	by	ADP
american_scientific_journal-766	233	52	soc	soc	NOUN
american_scientific_journal-766	233	53	in	in	ADP
american_scientific_journal-766	233	54	any	any	DET
american_scientific_journal-766	233	55	subgroup	subgroup	NOUN
american_scientific_journal-766	233	56	[	[	X
american_scientific_journal-766	233	57	77	77	NUM
american_scientific_journal-766	233	58	]	]	PUNCT
american_scientific_journal-766	233	59	.	.	PUNCT
american_scientific_journal-766	234	1	the	the	DET
american_scientific_journal-766	234	2	efficacy	efficacy	NOUN
american_scientific_journal-766	234	3	of	of	ADP
american_scientific_journal-766	234	4	the	the	DET
american_scientific_journal-766	234	5	sof	sof	PROPN
american_scientific_journal-766	234	6	/	/	SYM
american_scientific_journal-766	234	7	rbv	rbv	NOUN
american_scientific_journal-766	234	8	ifn	ifn	NOUN
american_scientific_journal-766	234	9	-	-	PUNCT
american_scientific_journal-766	234	10	free	free	ADJ
american_scientific_journal-766	234	11	combination	combination	NOUN
american_scientific_journal-766	234	12	in	in	ADP
american_scientific_journal-766	234	13	patients	patient	NOUN
american_scientific_journal-766	234	14	with	with	ADP
american_scientific_journal-766	234	15	a	a	DET
american_scientific_journal-766	234	16	previous	previous	ADJ
american_scientific_journal-766	234	17	treatment	treatment	NOUN
american_scientific_journal-766	234	18	failure	failure	NOUN
american_scientific_journal-766	234	19	to	to	ADP
american_scientific_journal-766	234	20	pegifn	pegifn	NOUN
american_scientific_journal-766	234	21	/	/	SYM
american_scientific_journal-766	234	22	rbv	rbv	NOUN
american_scientific_journal-766	234	23	was	be	AUX
american_scientific_journal-766	234	24	investigated	investigate	VERB
american_scientific_journal-766	234	25	in	in	ADP
american_scientific_journal-766	234	26	the	the	DET
american_scientific_journal-766	234	27	fusion	fusion	NOUN
american_scientific_journal-766	234	28	trial	trial	NOUN
american_scientific_journal-766	234	29	.	.	PUNCT
american_scientific_journal-766	235	1	overall	overall	ADJ
american_scientific_journal-766	235	2	svr	svr	PROPN
american_scientific_journal-766	235	3	in	in	ADP
american_scientific_journal-766	235	4	treatment	treatment	NOUN
american_scientific_journal-766	235	5	experienced	experience	VERB
american_scientific_journal-766	235	6	patients	patient	NOUN
american_scientific_journal-766	235	7	with	with	ADP
american_scientific_journal-766	235	8	sof	sof	VERB
american_scientific_journal-766	235	9	/	/	SYM
american_scientific_journal-766	235	10	rbv	rbv	NOUN
american_scientific_journal-766	235	11	was	be	AUX
american_scientific_journal-766	235	12	significantly	significantly	ADV
american_scientific_journal-766	235	13	lower	low	ADJ
american_scientific_journal-766	235	14	in	in	ADP
american_scientific_journal-766	235	15	the	the	DET
american_scientific_journal-766	235	16	12	12	NUM
american_scientific_journal-766	235	17	-	-	PUNCT
american_scientific_journal-766	235	18	week	week	NOUN
american_scientific_journal-766	235	19	compared	compare	VERB
american_scientific_journal-766	235	20	to	to	ADP
american_scientific_journal-766	235	21	16	16	NUM
american_scientific_journal-766	235	22	-	-	PUNCT
american_scientific_journal-766	235	23	week	week	NOUN
american_scientific_journal-766	235	24	arms	arm	NOUN
american_scientific_journal-766	235	25	(	(	PUNCT
american_scientific_journal-766	235	26	50	50	NUM
american_scientific_journal-766	235	27	%	%	NOUN
american_scientific_journal-766	235	28	vs	vs	ADP
american_scientific_journal-766	235	29	73	73	NUM
american_scientific_journal-766	235	30	%	%	NOUN
american_scientific_journal-766	235	31	)	)	PUNCT
american_scientific_journal-766	235	32	.	.	PUNCT
american_scientific_journal-766	236	1	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	236	2	and	and	CCONJ
american_scientific_journal-766	236	3	hcv	hcv	PROPN
american_scientific_journal-766	236	4	genotype	genotype	NOUN
american_scientific_journal-766	236	5	3	3	NUM
american_scientific_journal-766	236	6	were	be	AUX
american_scientific_journal-766	236	7	confirmed	confirm	VERB
american_scientific_journal-766	236	8	as	as	ADP
american_scientific_journal-766	236	9	predictors	predictor	NOUN
american_scientific_journal-766	236	10	of	of	ADP
american_scientific_journal-766	236	11	treatment	treatment	NOUN
american_scientific_journal-766	236	12	failure	failure	NOUN
american_scientific_journal-766	236	13	:	:	PUNCT
american_scientific_journal-766	236	14	indeed	indeed	ADV
american_scientific_journal-766	236	15	,	,	PUNCT
american_scientific_journal-766	236	16	in	in	ADP
american_scientific_journal-766	236	17	the	the	DET
american_scientific_journal-766	236	18	two	two	NUM
american_scientific_journal-766	236	19	treatment	treatment	NOUN
american_scientific_journal-766	236	20	arms	arm	NOUN
american_scientific_journal-766	236	21	(	(	PUNCT
american_scientific_journal-766	236	22	12/16	12/16	NUM
american_scientific_journal-766	236	23	weeks	week	NOUN
american_scientific_journal-766	236	24	)	)	PUNCT
american_scientific_journal-766	236	25	svr	svr	PROPN
american_scientific_journal-766	236	26	rates	rate	NOUN
american_scientific_journal-766	236	27	were	be	AUX
american_scientific_journal-766	236	28	respectively	respectively	ADV
american_scientific_journal-766	236	29	96%/100	96%/100	NUM
american_scientific_journal-766	236	30	%	%	NOUN
american_scientific_journal-766	236	31	in	in	ADP
american_scientific_journal-766	236	32	non	non	ADJ
american_scientific_journal-766	236	33	-	-	ADJ
american_scientific_journal-766	236	34	cirrhotic	cirrhotic	ADJ
american_scientific_journal-766	236	35	vs	vs	ADP
american_scientific_journal-766	236	36	60%/78	60%/78	NOUN
american_scientific_journal-766	236	37	%	%	NOUN
american_scientific_journal-766	236	38	in	in	ADP
american_scientific_journal-766	236	39	cirrhotic	cirrhotic	ADJ
american_scientific_journal-766	236	40	hcv-2	hcv-2	PUNCT
american_scientific_journal-766	236	41	patients	patient	NOUN
american_scientific_journal-766	236	42	,	,	PUNCT
american_scientific_journal-766	236	43	while	while	SCONJ
american_scientific_journal-766	236	44	in	in	ADP
american_scientific_journal-766	236	45	hcv-3	hcv-3	NOUN
american_scientific_journal-766	236	46	patients	patient	NOUN
american_scientific_journal-766	236	47	,	,	PUNCT
american_scientific_journal-766	236	48	svr	svr	PROPN
american_scientific_journal-766	236	49	decreased	decrease	VERB
american_scientific_journal-766	236	50	to	to	ADP
american_scientific_journal-766	236	51	37%/63	37%/63	ADJ
american_scientific_journal-766	236	52	%	%	NOUN
american_scientific_journal-766	236	53	in	in	ADP
american_scientific_journal-766	236	54	non	non	NOUN
american_scientific_journal-766	236	55	-	-	NOUN
american_scientific_journal-766	236	56	cirrhotics	cirrhotic	NOUN
american_scientific_journal-766	236	57	vs	vs	ADP
american_scientific_journal-766	236	58	19%/61	19%/61	ADJ
american_scientific_journal-766	236	59	%	%	NOUN
american_scientific_journal-766	236	60	in	in	ADP
american_scientific_journal-766	236	61	cirrhotics	cirrhotic	NOUN
american_scientific_journal-766	237	1	[	[	X
american_scientific_journal-766	237	2	70	70	NUM
american_scientific_journal-766	237	3	]	]	PUNCT
american_scientific_journal-766	237	4	.	.	PUNCT
american_scientific_journal-766	238	1	in	in	ADP
american_scientific_journal-766	238	2	another	another	DET
american_scientific_journal-766	238	3	phase	phase	NOUN
american_scientific_journal-766	238	4	iii	iii	NOUN
american_scientific_journal-766	238	5	,	,	PUNCT
american_scientific_journal-766	238	6	placebo	placebo	NOUN
american_scientific_journal-766	238	7	-	-	PUNCT
american_scientific_journal-766	238	8	controlled	control	VERB
american_scientific_journal-766	238	9	trial	trial	NOUN
american_scientific_journal-766	238	10	named	name	VERB
american_scientific_journal-766	238	11	positron	positron	NOUN
american_scientific_journal-766	238	12	,	,	PUNCT
american_scientific_journal-766	238	13	278	278	NUM
american_scientific_journal-766	238	14	patients	patient	NOUN
american_scientific_journal-766	238	15	with	with	ADP
american_scientific_journal-766	238	16	chc	chc	PROPN
american_scientific_journal-766	238	17	genotype	genotype	NOUN
american_scientific_journal-766	238	18	2	2	NUM
american_scientific_journal-766	238	19	or	or	CCONJ
american_scientific_journal-766	238	20	3	3	NUM
american_scientific_journal-766	238	21	who	who	PRON
american_scientific_journal-766	238	22	were	be	AUX
american_scientific_journal-766	238	23	interferon	interferon	ADJ
american_scientific_journal-766	238	24	intolerant	intolerant	ADJ
american_scientific_journal-766	238	25	or	or	CCONJ
american_scientific_journal-766	238	26	ineligible	ineligible	ADJ
american_scientific_journal-766	238	27	or	or	CCONJ
american_scientific_journal-766	238	28	had	have	AUX
american_scientific_journal-766	238	29	refused	refuse	VERB
american_scientific_journal-766	238	30	pegifn	pegifn	NOUN
american_scientific_journal-766	238	31	therapy	therapy	NOUN
american_scientific_journal-766	238	32	were	be	AUX
american_scientific_journal-766	238	33	randomized	randomize	VERB
american_scientific_journal-766	238	34	to	to	PART
american_scientific_journal-766	238	35	receive	receive	VERB
american_scientific_journal-766	238	36	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	238	37	plus	plus	CCONJ
american_scientific_journal-766	238	38	weight	weight	NOUN
american_scientific_journal-766	238	39	-	-	PUNCT
american_scientific_journal-766	238	40	based	base	VERB
american_scientific_journal-766	238	41	rbv	rbv	NOUN
american_scientific_journal-766	238	42	(	(	PUNCT
american_scientific_journal-766	238	43	n=207	n=207	NOUN
american_scientific_journal-766	238	44	)	)	PUNCT
american_scientific_journal-766	238	45	or	or	CCONJ
american_scientific_journal-766	238	46	placebo	placebo	NOUN
american_scientific_journal-766	238	47	(	(	PUNCT
american_scientific_journal-766	238	48	n=71	n=71	NOUN
american_scientific_journal-766	238	49	)	)	PUNCT
american_scientific_journal-766	238	50	for	for	ADP
american_scientific_journal-766	238	51	12	12	NUM
american_scientific_journal-766	238	52	weeks	week	NOUN
american_scientific_journal-766	238	53	.	.	PUNCT
american_scientific_journal-766	239	1	svr	svr	PROPN
american_scientific_journal-766	239	2	was	be	AUX
american_scientific_journal-766	239	3	achieved	achieve	VERB
american_scientific_journal-766	239	4	in	in	ADP
american_scientific_journal-766	239	5	78	78	NUM
american_scientific_journal-766	239	6	%	%	NOUN
american_scientific_journal-766	239	7	of	of	ADP
american_scientific_journal-766	239	8	patients	patient	NOUN
american_scientific_journal-766	239	9	in	in	ADP
american_scientific_journal-766	239	10	the	the	DET
american_scientific_journal-766	239	11	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	239	12	arm	arm	NOUN
american_scientific_journal-766	239	13	and	and	CCONJ
american_scientific_journal-766	239	14	0	0	NUM
american_scientific_journal-766	239	15	%	%	NOUN
american_scientific_journal-766	239	16	in	in	ADP
american_scientific_journal-766	239	17	the	the	DET
american_scientific_journal-766	239	18	placebo	placebo	NOUN
american_scientific_journal-766	239	19	arm	arm	NOUN
american_scientific_journal-766	239	20	.	.	PUNCT
american_scientific_journal-766	240	1	svr	svr	PROPN
american_scientific_journal-766	240	2	rate	rate	NOUN
american_scientific_journal-766	240	3	was	be	AUX
american_scientific_journal-766	240	4	significantly	significantly	ADV
american_scientific_journal-766	240	5	higher	high	ADJ
american_scientific_journal-766	240	6	in	in	ADP
american_scientific_journal-766	240	7	genotype	genotype	NOUN
american_scientific_journal-766	240	8	2	2	NUM
american_scientific_journal-766	240	9	than	than	ADP
american_scientific_journal-766	240	10	genotype	genotype	NOUN
american_scientific_journal-766	240	11	3	3	NUM
american_scientific_journal-766	240	12	patients	patient	NOUN
american_scientific_journal-766	240	13	(	(	PUNCT
american_scientific_journal-766	240	14	93	93	NUM
american_scientific_journal-766	240	15	%	%	NOUN
american_scientific_journal-766	240	16	vs.	vs.	ADP
american_scientific_journal-766	240	17	61	61	NUM
american_scientific_journal-766	240	18	%	%	NOUN
american_scientific_journal-766	240	19	,	,	PUNCT
american_scientific_journal-766	240	20	p<0.001	p<0.001	PROPN
american_scientific_journal-766	240	21	)	)	PUNCT
american_scientific_journal-766	240	22	.	.	PUNCT
american_scientific_journal-766	241	1	the	the	DET
american_scientific_journal-766	241	2	presence	presence	NOUN
american_scientific_journal-766	241	3	of	of	ADP
american_scientific_journal-766	241	4	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	241	5	did	do	AUX
american_scientific_journal-766	241	6	not	not	PART
american_scientific_journal-766	241	7	affect	affect	VERB
american_scientific_journal-766	241	8	the	the	DET
american_scientific_journal-766	241	9	svr	svr	PROPN
american_scientific_journal-766	241	10	rates	rate	NOUN
american_scientific_journal-766	241	11	in	in	ADP
american_scientific_journal-766	241	12	genotype	genotype	NOUN
american_scientific_journal-766	241	13	2	2	NUM
american_scientific_journal-766	241	14	patients	patient	NOUN
american_scientific_journal-766	241	15	(	(	PUNCT
american_scientific_journal-766	241	16	94	94	NUM
american_scientific_journal-766	241	17	%	%	NOUN
american_scientific_journal-766	241	18	vs.	vs.	ADP
american_scientific_journal-766	241	19	92	92	NUM
american_scientific_journal-766	241	20	%	%	NOUN
american_scientific_journal-766	241	21	)	)	PUNCT
american_scientific_journal-766	241	22	,	,	PUNCT
american_scientific_journal-766	241	23	but	but	CCONJ
american_scientific_journal-766	241	24	it	it	PRON
american_scientific_journal-766	241	25	had	have	VERB
american_scientific_journal-766	241	26	a	a	DET
american_scientific_journal-766	241	27	great	great	ADJ
american_scientific_journal-766	241	28	impact	impact	NOUN
american_scientific_journal-766	241	29	on	on	ADP
american_scientific_journal-766	241	30	the	the	DET
american_scientific_journal-766	241	31	svr	svr	PROPN
american_scientific_journal-766	241	32	rates	rate	NOUN
american_scientific_journal-766	241	33	in	in	ADP
american_scientific_journal-766	241	34	genotype	genotype	NOUN
american_scientific_journal-766	241	35	3	3	NUM
american_scientific_journal-766	241	36	patients	patient	NOUN
american_scientific_journal-766	241	37	(	(	PUNCT
american_scientific_journal-766	241	38	21	21	NUM
american_scientific_journal-766	241	39	%	%	NOUN
american_scientific_journal-766	241	40	vs.	vs.	ADP
american_scientific_journal-766	241	41	68	68	NUM
american_scientific_journal-766	241	42	%	%	NOUN
american_scientific_journal-766	241	43	,	,	PUNCT
american_scientific_journal-766	241	44	p=0.002	p=0.002	NOUN
american_scientific_journal-766	241	45	)	)	PUNCT
american_scientific_journal-766	242	1	[	[	X
american_scientific_journal-766	242	2	70	70	NUM
american_scientific_journal-766	242	3	]	]	PUNCT
american_scientific_journal-766	242	4	.	.	PUNCT
american_scientific_journal-766	243	1	concerning	concern	VERB
american_scientific_journal-766	243	2	safety	safety	NOUN
american_scientific_journal-766	243	3	,	,	PUNCT
american_scientific_journal-766	243	4	the	the	DET
american_scientific_journal-766	243	5	combination	combination	NOUN
american_scientific_journal-766	243	6	of	of	ADP
american_scientific_journal-766	243	7	sof	sof	PROPN
american_scientific_journal-766	243	8	/	/	SYM
american_scientific_journal-766	243	9	rbv	rbv	NOUN
american_scientific_journal-766	243	10	showed	show	VERB
american_scientific_journal-766	243	11	an	an	DET
american_scientific_journal-766	243	12	optimal	optimal	ADJ
american_scientific_journal-766	243	13	tolerability	tolerability	NOUN
american_scientific_journal-766	243	14	profile	profile	NOUN
american_scientific_journal-766	243	15	:	:	PUNCT
american_scientific_journal-766	243	16	the	the	DET
american_scientific_journal-766	243	17	most	most	ADV
american_scientific_journal-766	243	18	frequent	frequent	ADJ
american_scientific_journal-766	243	19	adverse	adverse	ADJ
american_scientific_journal-766	243	20	events	event	NOUN
american_scientific_journal-766	243	21	were	be	AUX
american_scientific_journal-766	243	22	fatigue	fatigue	NOUN
american_scientific_journal-766	243	23	(	(	PUNCT
american_scientific_journal-766	243	24	44	44	NUM
american_scientific_journal-766	243	25	%	%	NOUN
american_scientific_journal-766	243	26	)	)	PUNCT
american_scientific_journal-766	243	27	,	,	PUNCT
american_scientific_journal-766	243	28	nausea	nausea	NOUN
american_scientific_journal-766	243	29	(	(	PUNCT
american_scientific_journal-766	243	30	22	22	NUM
american_scientific_journal-766	243	31	%	%	NOUN
american_scientific_journal-766	243	32	)	)	PUNCT
american_scientific_journal-766	243	33	,	,	PUNCT
american_scientific_journal-766	243	34	headache	headache	NOUN
american_scientific_journal-766	243	35	(	(	PUNCT
american_scientific_journal-766	243	36	21	21	NUM
american_scientific_journal-766	243	37	%	%	NOUN
american_scientific_journal-766	243	38	)	)	PUNCT
american_scientific_journal-766	243	39	,	,	PUNCT
american_scientific_journal-766	243	40	insomnia	insomnia	NOUN
american_scientific_journal-766	243	41	(	(	PUNCT
american_scientific_journal-766	243	42	19	19	NUM
american_scientific_journal-766	243	43	%	%	NOUN
american_scientific_journal-766	243	44	)	)	PUNCT
american_scientific_journal-766	243	45	,	,	PUNCT
american_scientific_journal-766	243	46	and	and	CCONJ
american_scientific_journal-766	243	47	pruritus	pruritus	PROPN
american_scientific_journal-766	243	48	(	(	PUNCT
american_scientific_journal-766	243	49	11	11	NUM
american_scientific_journal-766	243	50	%	%	NOUN
american_scientific_journal-766	243	51	)	)	PUNCT
american_scientific_journal-766	243	52	,	,	PUNCT
american_scientific_journal-766	243	53	mainly	mainly	ADV
american_scientific_journal-766	243	54	consistent	consistent	ADJ
american_scientific_journal-766	243	55	with	with	ADP
american_scientific_journal-766	243	56	rbv	rbv	NOUN
american_scientific_journal-766	243	57	.	.	PUNCT
american_scientific_journal-766	244	1	hemoglobin	hemoglobin	NOUN
american_scientific_journal-766	244	2	decline	decline	VERB
american_scientific_journal-766	244	3	<	<	X
american_scientific_journal-766	244	4	10	10	NUM
american_scientific_journal-766	244	5	g	g	NOUN
american_scientific_journal-766	244	6	/	/	SYM
american_scientific_journal-766	244	7	dl	dl	PROPN
american_scientific_journal-766	244	8	occurred	occur	VERB
american_scientific_journal-766	244	9	in	in	ADP
american_scientific_journal-766	244	10	only	only	ADV
american_scientific_journal-766	244	11	7	7	NUM
american_scientific_journal-766	244	12	%	%	NOUN
american_scientific_journal-766	244	13	of	of	ADP
american_scientific_journal-766	244	14	patients	patient	NOUN
american_scientific_journal-766	244	15	(	(	PUNCT
american_scientific_journal-766	244	16	<	<	X
american_scientific_journal-766	244	17	8.5	8.5	NUM
american_scientific_journal-766	244	18	g	g	NOUN
american_scientific_journal-766	244	19	/	/	SYM
american_scientific_journal-766	244	20	dl	dl	PROPN
american_scientific_journal-766	244	21	in	in	ADP
american_scientific_journal-766	244	22	1	1	NUM
american_scientific_journal-766	244	23	%	%	NOUN
american_scientific_journal-766	244	24	)	)	PUNCT
american_scientific_journal-766	244	25	,	,	PUNCT
american_scientific_journal-766	244	26	while	while	SCONJ
american_scientific_journal-766	244	27	no	no	DET
american_scientific_journal-766	244	28	reduction	reduction	NOUN
american_scientific_journal-766	244	29	in	in	ADP
american_scientific_journal-766	244	30	platelets	platelet	NOUN
american_scientific_journal-766	244	31	and	and	CCONJ
american_scientific_journal-766	244	32	neutrophil	neutrophil	ADJ
american_scientific_journal-766	244	33	values	value	NOUN
american_scientific_journal-766	244	34	were	be	AUX
american_scientific_journal-766	244	35	reported	report	VERB
american_scientific_journal-766	244	36	[	[	X
american_scientific_journal-766	244	37	70	70	NUM
american_scientific_journal-766	244	38	]	]	PUNCT
american_scientific_journal-766	244	39	.	.	PUNCT
american_scientific_journal-766	245	1	in	in	ADP
american_scientific_journal-766	245	2	a	a	DET
american_scientific_journal-766	245	3	third	third	ADJ
american_scientific_journal-766	245	4	phase	phase	NOUN
american_scientific_journal-766	245	5	iii	iii	NOUN
american_scientific_journal-766	245	6	trial	trial	NOUN
american_scientific_journal-766	245	7	named	name	VERB
american_scientific_journal-766	245	8	valence	valence	NOUN
american_scientific_journal-766	245	9	including	include	VERB
american_scientific_journal-766	245	10	genotype	genotype	NOUN
american_scientific_journal-766	245	11	2	2	NUM
american_scientific_journal-766	245	12	and	and	CCONJ
american_scientific_journal-766	245	13	3	3	NUM
american_scientific_journal-766	245	14	naïve	naïve	ADJ
american_scientific_journal-766	245	15	chc	chc	NOUN
american_scientific_journal-766	245	16	patients	patient	NOUN
american_scientific_journal-766	245	17	,	,	PUNCT
american_scientific_journal-766	245	18	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	245	19	plus	plus	CCONJ
american_scientific_journal-766	245	20	weight	weight	NOUN
american_scientific_journal-766	245	21	-	-	PUNCT
american_scientific_journal-766	245	22	based	base	VERB
american_scientific_journal-766	245	23	rbv	rbv	NOUN
american_scientific_journal-766	245	24	was	be	AUX
american_scientific_journal-766	245	25	given	give	VERB
american_scientific_journal-766	245	26	for	for	ADP
american_scientific_journal-766	245	27	12	12	NUM
american_scientific_journal-766	245	28	weeks	week	NOUN
american_scientific_journal-766	245	29	in	in	ADP
american_scientific_journal-766	245	30	genotype	genotype	NOUN
american_scientific_journal-766	245	31	2	2	NUM
american_scientific_journal-766	245	32	(	(	PUNCT
american_scientific_journal-766	245	33	n=32	n=32	PROPN
american_scientific_journal-766	245	34	)	)	PUNCT
american_scientific_journal-766	245	35	and	and	CCONJ
american_scientific_journal-766	245	36	for	for	ADP
american_scientific_journal-766	245	37	24	24	NUM
american_scientific_journal-766	245	38	weeks	week	NOUN
american_scientific_journal-766	245	39	in	in	ADP
american_scientific_journal-766	245	40	genotype	genotype	NOUN
american_scientific_journal-766	245	41	3	3	NUM
american_scientific_journal-766	245	42	patients	patient	NOUN
american_scientific_journal-766	245	43	(	(	PUNCT
american_scientific_journal-766	245	44	n=105	n=105	PROPN
american_scientific_journal-766	245	45	)	)	PUNCT
american_scientific_journal-766	245	46	.	.	PUNCT
american_scientific_journal-766	246	1	svr	svr	PROPN
american_scientific_journal-766	246	2	was	be	AUX
american_scientific_journal-766	246	3	achieved	achieve	VERB
american_scientific_journal-766	246	4	in	in	ADP
american_scientific_journal-766	246	5	97	97	NUM
american_scientific_journal-766	246	6	%	%	NOUN
american_scientific_journal-766	246	7	of	of	ADP
american_scientific_journal-766	246	8	genotype	genotype	NOUN
american_scientific_journal-766	246	9	2	2	NUM
american_scientific_journal-766	246	10	(	(	PUNCT
american_scientific_journal-766	246	11	non	non	NOUN
american_scientific_journal-766	246	12	-	-	NOUN
american_scientific_journal-766	246	13	cirrhotics	cirrhotic	NOUN
american_scientific_journal-766	246	14	:	:	PUNCT
american_scientific_journal-766	246	15	97	97	NUM
american_scientific_journal-766	246	16	%	%	NOUN
american_scientific_journal-766	246	17	,	,	PUNCT
american_scientific_journal-766	246	18	cirrhotics	cirrhotic	NOUN
american_scientific_journal-766	246	19	:	:	PUNCT
american_scientific_journal-766	246	20	100	100	NUM
american_scientific_journal-766	246	21	%	%	NOUN
american_scientific_journal-766	246	22	)	)	PUNCT
american_scientific_journal-766	246	23	and	and	CCONJ
american_scientific_journal-766	246	24	93	93	NUM
american_scientific_journal-766	246	25	%	%	NOUN
american_scientific_journal-766	246	26	of	of	ADP
american_scientific_journal-766	246	27	genotype	genotype	NOUN
american_scientific_journal-766	246	28	3	3	NUM
american_scientific_journal-766	246	29	patients	patient	NOUN
american_scientific_journal-766	246	30	(	(	PUNCT
american_scientific_journal-766	246	31	non	non	NOUN
american_scientific_journal-766	246	32	-	-	NOUN
american_scientific_journal-766	246	33	cirrhotics	cirrhotic	NOUN
american_scientific_journal-766	246	34	:	:	PUNCT
american_scientific_journal-766	246	35	94	94	NUM
american_scientific_journal-766	246	36	%	%	NOUN
american_scientific_journal-766	246	37	,	,	PUNCT
american_scientific_journal-766	246	38	cirrhotics	cirrhotic	NOUN
american_scientific_journal-766	246	39	:	:	PUNCT
american_scientific_journal-766	246	40	92	92	NUM
american_scientific_journal-766	246	41	%	%	NOUN
american_scientific_journal-766	246	42	)	)	PUNCT
american_scientific_journal-766	246	43	.	.	PUNCT
american_scientific_journal-766	247	1	the	the	DET
american_scientific_journal-766	247	2	rates	rate	NOUN
american_scientific_journal-766	247	3	of	of	ADP
american_scientific_journal-766	247	4	discontinuation	discontinuation	NOUN
american_scientific_journal-766	247	5	were	be	AUX
american_scientific_journal-766	247	6	negligible	negligible	ADJ
american_scientific_journal-766	247	7	without	without	ADP
american_scientific_journal-766	247	8	evidence	evidence	NOUN
american_scientific_journal-766	247	9	of	of	ADP
american_scientific_journal-766	247	10	viral	viral	ADJ
american_scientific_journal-766	247	11	resistance	resistance	NOUN
american_scientific_journal-766	247	12	among	among	ADP
american_scientific_journal-766	247	13	the	the	DET
american_scientific_journal-766	247	14	patients	patient	NOUN
american_scientific_journal-766	247	15	who	who	PRON
american_scientific_journal-766	247	16	relapsed	relapse	VERB
american_scientific_journal-766	247	17	after	after	ADP
american_scientific_journal-766	247	18	treatment	treatment	NOUN
american_scientific_journal-766	247	19	[	[	X
american_scientific_journal-766	247	20	78	78	NUM
american_scientific_journal-766	247	21	]	]	PUNCT
american_scientific_journal-766	247	22	.	.	PUNCT
american_scientific_journal-766	248	1	2.2.5.2	2.2.5.2	X
american_scientific_journal-766	248	2	.	.	PROPN
american_scientific_journal-766	248	3	sof	sof	PROPN
american_scientific_journal-766	248	4	in	in	ADP
american_scientific_journal-766	248	5	combination	combination	NOUN
american_scientific_journal-766	248	6	with	with	ADP
american_scientific_journal-766	248	7	other	other	ADJ
american_scientific_journal-766	248	8	daas	daas	NOUN
american_scientific_journal-766	248	9	overall	overall	ADV
american_scientific_journal-766	248	10	,	,	PUNCT
american_scientific_journal-766	248	11	sof	sof	PROPN
american_scientific_journal-766	248	12	appears	appear	VERB
american_scientific_journal-766	248	13	to	to	PART
american_scientific_journal-766	248	14	be	be	AUX
american_scientific_journal-766	248	15	an	an	DET
american_scientific_journal-766	248	16	attractive	attractive	ADJ
american_scientific_journal-766	248	17	choice	choice	NOUN
american_scientific_journal-766	248	18	to	to	PART
american_scientific_journal-766	248	19	serve	serve	VERB
american_scientific_journal-766	248	20	as	as	ADP
american_scientific_journal-766	248	21	a	a	DET
american_scientific_journal-766	248	22	backbone	backbone	NOUN
american_scientific_journal-766	248	23	for	for	ADP
american_scientific_journal-766	248	24	future	future	ADJ
american_scientific_journal-766	248	25	daa	daa	NOUN
american_scientific_journal-766	248	26	combinations	combination	NOUN
american_scientific_journal-766	248	27	.	.	PUNCT
american_scientific_journal-766	249	1	the	the	DET
american_scientific_journal-766	249	2	possibility	possibility	NOUN
american_scientific_journal-766	249	3	of	of	ADP
american_scientific_journal-766	249	4	developing	develop	VERB
american_scientific_journal-766	249	5	an	an	DET
american_scientific_journal-766	249	6	ifn	ifn	NOUN
american_scientific_journal-766	249	7	-	-	PUNCT
american_scientific_journal-766	249	8	free	free	ADJ
american_scientific_journal-766	249	9	regimen	regiman	NOUN
american_scientific_journal-766	249	10	for	for	ADP
american_scientific_journal-766	249	11	difficult	difficult	ADJ
american_scientific_journal-766	249	12	-	-	PUNCT
american_scientific_journal-766	249	13	to	to	ADP
american_scientific_journal-766	249	14	-	-	PUNCT
american_scientific_journal-766	249	15	treat	treat	NOUN
american_scientific_journal-766	249	16	genotypes	genotype	NOUN
american_scientific_journal-766	249	17	requires	require	VERB
american_scientific_journal-766	249	18	the	the	DET
american_scientific_journal-766	249	19	combination	combination	NOUN
american_scientific_journal-766	249	20	of	of	ADP
american_scientific_journal-766	249	21	different	different	ADJ
american_scientific_journal-766	249	22	daa	daa	NOUN
american_scientific_journal-766	249	23	classes	class	NOUN
american_scientific_journal-766	249	24	to	to	PART
american_scientific_journal-766	249	25	provide	provide	VERB
american_scientific_journal-766	249	26	high	high	ADJ
american_scientific_journal-766	249	27	antiviral	antiviral	ADJ
american_scientific_journal-766	249	28	efficacy	efficacy	NOUN
american_scientific_journal-766	249	29	as	as	ADV
american_scientific_journal-766	249	30	well	well	ADV
american_scientific_journal-766	249	31	as	as	ADP
american_scientific_journal-766	249	32	a	a	DET
american_scientific_journal-766	249	33	high	high	ADJ
american_scientific_journal-766	249	34	barrier	barrier	NOUN
american_scientific_journal-766	249	35	to	to	ADP
american_scientific_journal-766	249	36	resistance	resistance	NOUN
american_scientific_journal-766	249	37	.	.	PUNCT
american_scientific_journal-766	250	1	in	in	ADP
american_scientific_journal-766	250	2	another	another	DET
american_scientific_journal-766	250	3	openlabel	openlabel	NOUN
american_scientific_journal-766	250	4	,	,	PUNCT
american_scientific_journal-766	250	5	phase	phase	NOUN
american_scientific_journal-766	250	6	ii	ii	PROPN
american_scientific_journal-766	250	7	study	study	NOUN
american_scientific_journal-766	250	8	named	name	VERB
american_scientific_journal-766	250	9	lonestar	lonestar	PROPN
american_scientific_journal-766	250	10	,	,	PUNCT
american_scientific_journal-766	250	11	one	one	NUM
american_scientific_journal-766	250	12	tablet	tablet	NOUN
american_scientific_journal-766	250	13	co	co	NOUN
american_scientific_journal-766	250	14	-	-	NOUN
american_scientific_journal-766	250	15	formulation	formulation	NOUN
american_scientific_journal-766	250	16	of	of	ADP
american_scientific_journal-766	250	17	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	250	18	and	and	CCONJ
american_scientific_journal-766	250	19	ledipasvir	ledipasvir	PROPN
american_scientific_journal-766	250	20	(	(	PUNCT
american_scientific_journal-766	250	21	ns5a	ns5a	ADJ
american_scientific_journal-766	250	22	inhibitor	inhibitor	NOUN
american_scientific_journal-766	250	23	)	)	PUNCT
american_scientific_journal-766	250	24	with	with	ADP
american_scientific_journal-766	250	25	or	or	CCONJ
american_scientific_journal-766	250	26	without	without	ADP
american_scientific_journal-766	250	27	weight	weight	NOUN
american_scientific_journal-766	250	28	-	-	PUNCT
american_scientific_journal-766	250	29	based	base	VERB
american_scientific_journal-766	250	30	rbv	rbv	NOUN
american_scientific_journal-766	250	31	were	be	AUX
american_scientific_journal-766	250	32	given	give	VERB
american_scientific_journal-766	250	33	for	for	ADP
american_scientific_journal-766	250	34	8	8	NUM
american_scientific_journal-766	250	35	or	or	CCONJ
american_scientific_journal-766	250	36	12	12	NUM
american_scientific_journal-766	250	37	weeks	week	NOUN
american_scientific_journal-766	250	38	in	in	ADP
american_scientific_journal-766	250	39	100	100	NUM
american_scientific_journal-766	250	40	genotype	genotype	NOUN
american_scientific_journal-766	250	41	1	1	NUM
american_scientific_journal-766	250	42	chc	chc	NOUN
american_scientific_journal-766	250	43	patients	patient	NOUN
american_scientific_journal-766	250	44	who	who	PRON
american_scientific_journal-766	250	45	were	be	AUX
american_scientific_journal-766	250	46	treatment	treatment	NOUN
american_scientific_journal-766	250	47	-	-	PUNCT
american_scientific_journal-766	250	48	naïve	naïve	ADJ
american_scientific_journal-766	250	49	or	or	CCONJ
american_scientific_journal-766	250	50	had	have	AUX
american_scientific_journal-766	250	51	failed	fail	VERB
american_scientific_journal-766	250	52	a	a	DET
american_scientific_journal-766	250	53	course	course	NOUN
american_scientific_journal-766	250	54	with	with	ADP
american_scientific_journal-766	250	55	triple	triple	ADJ
american_scientific_journal-766	250	56	combination	combination	NOUN
american_scientific_journal-766	250	57	including	include	VERB
american_scientific_journal-766	250	58	a	a	DET
american_scientific_journal-766	250	59	1st	1st	ADJ
american_scientific_journal-766	250	60	generation	generation	NOUN
american_scientific_journal-766	250	61	protease	protease	NOUN
american_scientific_journal-766	250	62	inhibitor	inhibitor	NOUN
american_scientific_journal-766	250	63	.	.	PUNCT
american_scientific_journal-766	251	1	the	the	DET
american_scientific_journal-766	251	2	svr	svr	PROPN
american_scientific_journal-766	251	3	rates	rate	NOUN
american_scientific_journal-766	251	4	were	be	AUX
american_scientific_journal-766	251	5	95	95	NUM
american_scientific_journal-766	251	6	-	-	SYM
american_scientific_journal-766	251	7	100	100	NUM
american_scientific_journal-766	251	8	%	%	NOUN
american_scientific_journal-766	251	9	in	in	ADP
american_scientific_journal-766	251	10	all	all	DET
american_scientific_journal-766	251	11	subgroups	subgroup	NOUN
american_scientific_journal-766	251	12	regardless	regardless	ADV
american_scientific_journal-766	251	13	of	of	ADP
american_scientific_journal-766	251	14	previous	previous	ADJ
american_scientific_journal-766	251	15	treatment	treatment	NOUN
american_scientific_journal-766	251	16	history	history	NOUN
american_scientific_journal-766	251	17	or	or	CCONJ
american_scientific_journal-766	251	18	presence	presence	NOUN
american_scientific_journal-766	251	19	of	of	ADP
american_scientific_journal-766	251	20	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	251	21	.	.	PUNCT
american_scientific_journal-766	252	1	adverse	adverse	ADJ
american_scientific_journal-766	252	2	events	event	NOUN
american_scientific_journal-766	252	3	were	be	AUX
american_scientific_journal-766	252	4	rare	rare	ADJ
american_scientific_journal-766	252	5	and	and	CCONJ
american_scientific_journal-766	252	6	always	always	ADV
american_scientific_journal-766	252	7	mild	mild	ADJ
american_scientific_journal-766	252	8	(	(	PUNCT
american_scientific_journal-766	252	9	nausea	nausea	NOUN
american_scientific_journal-766	252	10	,	,	PUNCT
american_scientific_journal-766	252	11	anemia	anemia	NOUN
american_scientific_journal-766	252	12	and	and	CCONJ
american_scientific_journal-766	252	13	headache	headache	NOUN
american_scientific_journal-766	252	14	)	)	PUNCT
american_scientific_journal-766	252	15	,	,	PUNCT
american_scientific_journal-766	252	16	while	while	SCONJ
american_scientific_journal-766	252	17	one	one	NUM
american_scientific_journal-766	252	18	patient	patient	NOUN
american_scientific_journal-766	252	19	in	in	ADP
american_scientific_journal-766	252	20	the	the	DET
american_scientific_journal-766	252	21	rbvcontaining	rbvcontaine	VERB
american_scientific_journal-766	252	22	arm	arm	NOUN
american_scientific_journal-766	252	23	developed	develop	VERB
american_scientific_journal-766	252	24	severe	severe	ADJ
american_scientific_journal-766	252	25	anemia	anemia	NOUN
american_scientific_journal-766	253	1	[	[	X
american_scientific_journal-766	253	2	79	79	NUM
american_scientific_journal-766	253	3	]	]	PUNCT
american_scientific_journal-766	253	4	.	.	PUNCT
american_scientific_journal-766	254	1	in	in	ADP
american_scientific_journal-766	254	2	a	a	DET
american_scientific_journal-766	254	3	single	single	ADJ
american_scientific_journal-766	254	4	arm	arm	NOUN
american_scientific_journal-766	254	5	phase	phase	NOUN
american_scientific_journal-766	254	6	ii	ii	NOUN
american_scientific_journal-766	254	7	trial	trial	NOUN
american_scientific_journal-766	254	8	named	name	VERB
american_scientific_journal-766	254	9	lonestar-2	lonestar-2	PROPN
american_scientific_journal-766	254	10	,	,	PUNCT
american_scientific_journal-766	254	11	such	such	DET
american_scientific_journal-766	254	12	a	a	DET
american_scientific_journal-766	254	13	triple	triple	ADJ
american_scientific_journal-766	254	14	combination	combination	NOUN
american_scientific_journal-766	254	15	offered	offer	VERB
american_scientific_journal-766	254	16	svr	svr	PROPN
american_scientific_journal-766	254	17	rates	rate	NOUN
american_scientific_journal-766	254	18	of	of	ADP
american_scientific_journal-766	254	19	96	96	NUM
american_scientific_journal-766	254	20	%	%	NOUN
american_scientific_journal-766	254	21	(	(	PUNCT
american_scientific_journal-766	254	22	22/23	22/23	NUM
american_scientific_journal-766	254	23	)	)	PUNCT
american_scientific_journal-766	254	24	in	in	ADP
american_scientific_journal-766	254	25	genotype	genotype	NOUN
american_scientific_journal-766	254	26	2	2	NUM
american_scientific_journal-766	254	27	and	and	CCONJ
american_scientific_journal-766	254	28	of	of	ADP
american_scientific_journal-766	254	29	83	83	NUM
american_scientific_journal-766	254	30	%	%	NOUN
american_scientific_journal-766	254	31	(	(	PUNCT
american_scientific_journal-766	254	32	20/24	20/24	NUM
american_scientific_journal-766	254	33	)	)	PUNCT
american_scientific_journal-766	254	34	in	in	ADP
american_scientific_journal-766	254	35	genotype	genotype	NOUN
american_scientific_journal-766	254	36	3	3	NUM
american_scientific_journal-766	254	37	patients	patient	NOUN
american_scientific_journal-766	254	38	[	[	X
american_scientific_journal-766	254	39	80	80	NUM
american_scientific_journal-766	254	40	]	]	PUNCT
american_scientific_journal-766	254	41	.	.	PUNCT
american_scientific_journal-766	255	1	13	13	NUM
american_scientific_journal-766	255	2	american	american	ADJ
american_scientific_journal-766	255	3	scientific	scientific	ADJ
american_scientific_journal-766	255	4	research	research	NOUN
american_scientific_journal-766	255	5	journal	journal	NOUN
american_scientific_journal-766	255	6	for	for	ADP
american_scientific_journal-766	255	7	engineering	engineering	NOUN
american_scientific_journal-766	255	8	,	,	PUNCT
american_scientific_journal-766	255	9	technology	technology	NOUN
american_scientific_journal-766	255	10	,	,	PUNCT
american_scientific_journal-766	255	11	and	and	CCONJ
american_scientific_journal-766	255	12	sciences	science	NOUN
american_scientific_journal-766	255	13	(	(	PUNCT
american_scientific_journal-766	255	14	asrjets	asrjet	NOUN
american_scientific_journal-766	255	15	)	)	PUNCT
american_scientific_journal-766	255	16	(	(	PUNCT
american_scientific_journal-766	255	17	2015	2015	NUM
american_scientific_journal-766	255	18	)	)	PUNCT
american_scientific_journal-766	255	19	volume	volume	NOUN
american_scientific_journal-766	255	20	13	13	NUM
american_scientific_journal-766	255	21	,	,	PUNCT
american_scientific_journal-766	255	22	no	no	DET
american_scientific_journal-766	255	23	1	1	NUM
american_scientific_journal-766	255	24	,	,	PUNCT
american_scientific_journal-766	255	25	pp	pp	ADV
american_scientific_journal-766	255	26	1	1	NUM
american_scientific_journal-766	255	27	-	-	SYM
american_scientific_journal-766	255	28	23	23	NUM
american_scientific_journal-766	255	29	the	the	DET
american_scientific_journal-766	255	30	combination	combination	NOUN
american_scientific_journal-766	255	31	of	of	ADP
american_scientific_journal-766	255	32	12	12	NUM
american_scientific_journal-766	255	33	or	or	CCONJ
american_scientific_journal-766	255	34	24	24	NUM
american_scientific_journal-766	255	35	weeks	week	NOUN
american_scientific_journal-766	255	36	of	of	ADP
american_scientific_journal-766	255	37	sof	sof	PROPN
american_scientific_journal-766	255	38	plus	plus	CCONJ
american_scientific_journal-766	255	39	the	the	DET
american_scientific_journal-766	255	40	ns3	ns3	NOUN
american_scientific_journal-766	255	41	inhibitor	inhibitor	NOUN
american_scientific_journal-766	255	42	simeprevir	simeprevir	NOUN
american_scientific_journal-766	255	43	was	be	AUX
american_scientific_journal-766	255	44	evaluated	evaluate	VERB
american_scientific_journal-766	255	45	by	by	ADP
american_scientific_journal-766	255	46	the	the	DET
american_scientific_journal-766	255	47	cosmos	cosmos	PROPN
american_scientific_journal-766	255	48	phase	phase	NOUN
american_scientific_journal-766	255	49	ii	ii	PROPN
american_scientific_journal-766	255	50	study	study	NOUN
american_scientific_journal-766	255	51	,	,	PUNCT
american_scientific_journal-766	255	52	where	where	SCONJ
american_scientific_journal-766	255	53	an	an	DET
american_scientific_journal-766	255	54	overall	overall	ADJ
american_scientific_journal-766	255	55	93	93	NUM
american_scientific_journal-766	255	56	%	%	NOUN
american_scientific_journal-766	255	57	svr12	svr12	ADJ
american_scientific_journal-766	255	58	rate	rate	NOUN
american_scientific_journal-766	255	59	in	in	ADP
american_scientific_journal-766	255	60	non	non	ADJ
american_scientific_journal-766	255	61	-	-	ADJ
american_scientific_journal-766	255	62	cirrhotic	cirrhotic	ADJ
american_scientific_journal-766	255	63	hcv-1	hcv-1	X
american_scientific_journal-766	255	64	previous	previous	ADJ
american_scientific_journal-766	255	65	null	null	ADJ
american_scientific_journal-766	255	66	-	-	PUNCT
american_scientific_journal-766	255	67	responder	responder	NOUN
american_scientific_journal-766	255	68	to	to	PART
american_scientific_journal-766	255	69	pegifn	pegifn	NOUN
american_scientific_journal-766	255	70	/	/	SYM
american_scientific_journal-766	255	71	rbv	rbv	NOUN
american_scientific_journal-766	255	72	was	be	AUX
american_scientific_journal-766	255	73	obtained	obtain	VERB
american_scientific_journal-766	255	74	.	.	PUNCT
american_scientific_journal-766	256	1	interim	interim	ADJ
american_scientific_journal-766	256	2	analysis	analysis	NOUN
american_scientific_journal-766	256	3	of	of	ADP
american_scientific_journal-766	256	4	a	a	DET
american_scientific_journal-766	256	5	second	second	ADJ
american_scientific_journal-766	256	6	cohort	cohort	NOUN
american_scientific_journal-766	256	7	including	include	VERB
american_scientific_journal-766	256	8	cirrhotic	cirrhotic	ADJ
american_scientific_journal-766	256	9	hcv-1	hcv-1	X
american_scientific_journal-766	256	10	naïve	naïve	ADJ
american_scientific_journal-766	256	11	and	and	CCONJ
american_scientific_journal-766	256	12	nullresponder	nullresponder	NOUN
american_scientific_journal-766	256	13	patients	patient	NOUN
american_scientific_journal-766	256	14	showed	show	VERB
american_scientific_journal-766	256	15	100	100	NUM
american_scientific_journal-766	256	16	%	%	NOUN
american_scientific_journal-766	256	17	svr4	svr4	PROPN
american_scientific_journal-766	256	18	with	with	ADP
american_scientific_journal-766	256	19	the	the	DET
american_scientific_journal-766	256	20	12	12	NUM
american_scientific_journal-766	256	21	-	-	PUNCT
american_scientific_journal-766	256	22	week	week	NOUN
american_scientific_journal-766	256	23	regimen	regiman	NOUN
american_scientific_journal-766	257	1	[	[	X
american_scientific_journal-766	257	2	39	39	NUM
american_scientific_journal-766	257	3	]	]	PUNCT
american_scientific_journal-766	257	4	.	.	PUNCT
american_scientific_journal-766	258	1	the	the	DET
american_scientific_journal-766	258	2	two	two	NUM
american_scientific_journal-766	258	3	daa	daa	PROPN
american_scientific_journal-766	258	4	drug	drug	NOUN
american_scientific_journal-766	258	5	combinations	combination	NOUN
american_scientific_journal-766	258	6	,	,	PUNCT
american_scientific_journal-766	258	7	regardless	regardless	ADV
american_scientific_journal-766	258	8	of	of	ADP
american_scientific_journal-766	258	9	whether	whether	SCONJ
american_scientific_journal-766	258	10	rbv	rbv	NOUN
american_scientific_journal-766	258	11	was	be	AUX
american_scientific_journal-766	258	12	included	include	VERB
american_scientific_journal-766	258	13	,	,	PUNCT
american_scientific_journal-766	258	14	performed	perform	VERB
american_scientific_journal-766	258	15	impressively	impressively	ADV
american_scientific_journal-766	258	16	and	and	CCONJ
american_scientific_journal-766	258	17	led	lead	VERB
american_scientific_journal-766	258	18	to	to	PART
american_scientific_journal-766	258	19	svr	svr	VERB
american_scientific_journal-766	258	20	rates	rate	NOUN
american_scientific_journal-766	258	21	between	between	ADP
american_scientific_journal-766	258	22	79	79	NUM
american_scientific_journal-766	258	23	%	%	NOUN
american_scientific_journal-766	258	24	and	and	CCONJ
american_scientific_journal-766	258	25	100	100	NUM
american_scientific_journal-766	258	26	%	%	NOUN
american_scientific_journal-766	258	27	.	.	PUNCT
american_scientific_journal-766	259	1	recently	recently	ADV
american_scientific_journal-766	259	2	,	,	PUNCT
american_scientific_journal-766	259	3	the	the	DET
american_scientific_journal-766	259	4	fda	fda	PROPN
american_scientific_journal-766	259	5	granted	grant	VERB
american_scientific_journal-766	259	6	priority	priority	NOUN
american_scientific_journal-766	259	7	review	review	NOUN
american_scientific_journal-766	259	8	to	to	ADP
american_scientific_journal-766	259	9	gilead	gilead	PROPN
american_scientific_journal-766	259	10	’s	’s	PART
american_scientific_journal-766	259	11	new	new	ADJ
american_scientific_journal-766	259	12	drug	drug	NOUN
american_scientific_journal-766	259	13	application	application	NOUN
american_scientific_journal-766	259	14	for	for	ADP
american_scientific_journal-766	259	15	a	a	DET
american_scientific_journal-766	259	16	once	once	ADV
american_scientific_journal-766	259	17	-	-	PUNCT
american_scientific_journal-766	259	18	daily	daily	ADJ
american_scientific_journal-766	259	19	fixed	fix	VERB
american_scientific_journal-766	259	20	-	-	PUNCT
american_scientific_journal-766	259	21	dose	dose	NOUN
american_scientific_journal-766	259	22	combination	combination	NOUN
american_scientific_journal-766	259	23	of	of	ADP
american_scientific_journal-766	259	24	sof	sof	PROPN
american_scientific_journal-766	259	25	(	(	PUNCT
american_scientific_journal-766	259	26	400	400	NUM
american_scientific_journal-766	259	27	mg	mg	NUM
american_scientific_journal-766	259	28	)	)	PUNCT
american_scientific_journal-766	259	29	and	and	CCONJ
american_scientific_journal-766	259	30	ldv	ldv	PROPN
american_scientific_journal-766	259	31	(	(	PUNCT
american_scientific_journal-766	259	32	90	90	NUM
american_scientific_journal-766	259	33	mg	mg	NUM
american_scientific_journal-766	259	34	)	)	PUNCT
american_scientific_journal-766	259	35	for	for	ADP
american_scientific_journal-766	259	36	the	the	DET
american_scientific_journal-766	259	37	treatment	treatment	NOUN
american_scientific_journal-766	259	38	of	of	ADP
american_scientific_journal-766	259	39	chronic	chronic	ADJ
american_scientific_journal-766	259	40	hepatitis	hepatitis	NOUN
american_scientific_journal-766	259	41	c	c	PROPN
american_scientific_journal-766	259	42	genotype	genotype	NOUN
american_scientific_journal-766	259	43	1	1	NUM
american_scientific_journal-766	259	44	infection	infection	NOUN
american_scientific_journal-766	259	45	in	in	ADP
american_scientific_journal-766	259	46	adults	adult	NOUN
american_scientific_journal-766	259	47	called	call	VERB
american_scientific_journal-766	259	48	harvoni	harvoni	ADJ
american_scientific_journal-766	259	49	.	.	PUNCT
american_scientific_journal-766	260	1	furthermore	furthermore	ADV
american_scientific_journal-766	260	2	,	,	PUNCT
american_scientific_journal-766	260	3	it	it	PRON
american_scientific_journal-766	260	4	now	now	ADV
american_scientific_journal-766	260	5	appears	appear	VERB
american_scientific_journal-766	260	6	that	that	PRON
american_scientific_journal-766	260	7	sof	sof	VERB
american_scientific_journal-766	260	8	in	in	ADP
american_scientific_journal-766	260	9	combination	combination	NOUN
american_scientific_journal-766	260	10	with	with	ADP
american_scientific_journal-766	260	11	ldv	ldv	PROPN
american_scientific_journal-766	260	12	for	for	ADP
american_scientific_journal-766	260	13	8	8	NUM
american_scientific_journal-766	260	14	weeks	week	NOUN
american_scientific_journal-766	260	15	may	may	AUX
american_scientific_journal-766	260	16	be	be	AUX
american_scientific_journal-766	260	17	just	just	ADV
american_scientific_journal-766	260	18	as	as	ADV
american_scientific_journal-766	260	19	effective	effective	ADJ
american_scientific_journal-766	260	20	as	as	ADP
american_scientific_journal-766	260	21	12	12	NUM
american_scientific_journal-766	260	22	weeks	week	NOUN
american_scientific_journal-766	260	23	in	in	ADP
american_scientific_journal-766	260	24	genotype	genotype	NOUN
american_scientific_journal-766	260	25	1	1	NUM
american_scientific_journal-766	260	26	patients	patient	NOUN
american_scientific_journal-766	260	27	without	without	ADP
american_scientific_journal-766	260	28	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	260	29	,	,	PUNCT
american_scientific_journal-766	260	30	as	as	SCONJ
american_scientific_journal-766	260	31	established	establish	VERB
american_scientific_journal-766	260	32	by	by	ADP
american_scientific_journal-766	260	33	lonestar	lonestar	NOUN
american_scientific_journal-766	260	34	and	and	CCONJ
american_scientific_journal-766	260	35	ion-3	ion-3	PUNCT
american_scientific_journal-766	260	36	data	datum	NOUN
american_scientific_journal-766	260	37	.	.	PUNCT
american_scientific_journal-766	261	1	sof	sof	PROPN
american_scientific_journal-766	261	2	+	+	CCONJ
american_scientific_journal-766	261	3	dcv	dcv	NOUN
american_scientific_journal-766	261	4	were	be	AUX
american_scientific_journal-766	261	5	tested	test	VERB
american_scientific_journal-766	261	6	against	against	ADP
american_scientific_journal-766	261	7	genotypes	genotype	NOUN
american_scientific_journal-766	261	8	2	2	NUM
american_scientific_journal-766	261	9	and	and	CCONJ
american_scientific_journal-766	261	10	3	3	NUM
american_scientific_journal-766	261	11	.	.	PUNCT
american_scientific_journal-766	262	1	in	in	ADP
american_scientific_journal-766	262	2	particular	particular	ADJ
american_scientific_journal-766	262	3	,	,	PUNCT
american_scientific_journal-766	262	4	8	8	NUM
american_scientific_journal-766	262	5	-	-	SYM
american_scientific_journal-766	262	6	12	12	NUM
american_scientific_journal-766	262	7	week	week	NOUN
american_scientific_journal-766	262	8	courses	course	NOUN
american_scientific_journal-766	262	9	with	with	ADP
american_scientific_journal-766	262	10	the	the	DET
american_scientific_journal-766	262	11	combination	combination	NOUN
american_scientific_journal-766	262	12	of	of	ADP
american_scientific_journal-766	262	13	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	262	14	with	with	ADP
american_scientific_journal-766	262	15	a	a	DET
american_scientific_journal-766	262	16	potent	potent	ADJ
american_scientific_journal-766	262	17	ns5a	ns5a	ADJ
american_scientific_journal-766	262	18	inhibitor	inhibitor	NOUN
american_scientific_journal-766	262	19	(	(	PUNCT
american_scientific_journal-766	262	20	e.g.	e.g.	ADV
american_scientific_journal-766	262	21	ledipasvir	ledipasvir	NOUN
american_scientific_journal-766	262	22	or	or	CCONJ
american_scientific_journal-766	262	23	daclatasvir	daclatasvir	PROPN
american_scientific_journal-766	262	24	)	)	PUNCT
american_scientific_journal-766	262	25	or	or	CCONJ
american_scientific_journal-766	262	26	ns3	ns3	NOUN
american_scientific_journal-766	262	27	protease	protease	NOUN
american_scientific_journal-766	262	28	inhibitor	inhibitor	NOUN
american_scientific_journal-766	262	29	(	(	PUNCT
american_scientific_journal-766	262	30	e.g.	e.g.	ADV
american_scientific_journal-766	262	31	simeprevir	simeprevir	NOUN
american_scientific_journal-766	262	32	)	)	PUNCT
american_scientific_journal-766	262	33	have	have	AUX
american_scientific_journal-766	262	34	been	be	AUX
american_scientific_journal-766	262	35	shown	show	VERB
american_scientific_journal-766	262	36	to	to	PART
american_scientific_journal-766	262	37	achieve	achieve	VERB
american_scientific_journal-766	262	38	svr	svr	PROPN
american_scientific_journal-766	262	39	in	in	ADP
american_scientific_journal-766	262	40	almost	almost	ADV
american_scientific_journal-766	262	41	all	all	PRON
american_scientific_journal-766	262	42	genotype	genotype	NOUN
american_scientific_journal-766	262	43	1	1	NUM
american_scientific_journal-766	262	44	patients	patient	NOUN
american_scientific_journal-766	262	45	without	without	ADP
american_scientific_journal-766	262	46	safety	safety	NOUN
american_scientific_journal-766	262	47	and	and	CCONJ
american_scientific_journal-766	262	48	tolerability	tolerability	NOUN
american_scientific_journal-766	262	49	concerns	concern	NOUN
american_scientific_journal-766	262	50	[	[	X
american_scientific_journal-766	262	51	81	81	NUM
american_scientific_journal-766	262	52	]	]	PUNCT
american_scientific_journal-766	262	53	.	.	PUNCT
american_scientific_journal-766	263	1	its	its	PRON
american_scientific_journal-766	263	2	excellent	excellent	ADJ
american_scientific_journal-766	263	3	safety	safety	NOUN
american_scientific_journal-766	263	4	profile	profile	NOUN
american_scientific_journal-766	263	5	makes	make	VERB
american_scientific_journal-766	263	6	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	263	7	an	an	DET
american_scientific_journal-766	263	8	optimal	optimal	ADJ
american_scientific_journal-766	263	9	choice	choice	NOUN
american_scientific_journal-766	263	10	for	for	ADP
american_scientific_journal-766	263	11	patients	patient	NOUN
american_scientific_journal-766	263	12	with	with	ADP
american_scientific_journal-766	263	13	decompensated	decompensate	VERB
american_scientific_journal-766	263	14	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	263	15	and	and	CCONJ
american_scientific_journal-766	263	16	liver	liver	NOUN
american_scientific_journal-766	263	17	transplant	transplant	NOUN
american_scientific_journal-766	263	18	recipients	recipient	NOUN
american_scientific_journal-766	263	19	as	as	ADV
american_scientific_journal-766	263	20	well	well	ADV
american_scientific_journal-766	263	21	as	as	ADP
american_scientific_journal-766	263	22	for	for	ADP
american_scientific_journal-766	263	23	patients	patient	NOUN
american_scientific_journal-766	263	24	who	who	PRON
american_scientific_journal-766	263	25	can	can	AUX
american_scientific_journal-766	263	26	not	not	PART
american_scientific_journal-766	263	27	tolerate	tolerate	VERB
american_scientific_journal-766	263	28	interferon	interferon	NOUN
american_scientific_journal-766	263	29	and/or	and/or	CCONJ
american_scientific_journal-766	263	30	rbv	rbv	NOUN
american_scientific_journal-766	263	31	.	.	PUNCT
american_scientific_journal-766	264	1	the	the	DET
american_scientific_journal-766	264	2	safety	safety	NOUN
american_scientific_journal-766	264	3	profile	profile	NOUN
american_scientific_journal-766	264	4	was	be	AUX
american_scientific_journal-766	264	5	good	good	ADJ
american_scientific_journal-766	264	6	in	in	ADP
american_scientific_journal-766	264	7	all	all	DET
american_scientific_journal-766	264	8	the	the	DET
american_scientific_journal-766	264	9	patients	patient	NOUN
american_scientific_journal-766	264	10	,	,	PUNCT
american_scientific_journal-766	264	11	thus	thus	ADV
american_scientific_journal-766	264	12	suggesting	suggest	VERB
american_scientific_journal-766	264	13	that	that	SCONJ
american_scientific_journal-766	264	14	no	no	DET
american_scientific_journal-766	264	15	dosage	dosage	NOUN
american_scientific_journal-766	264	16	or	or	CCONJ
american_scientific_journal-766	264	17	interval	interval	NOUN
american_scientific_journal-766	264	18	modification	modification	NOUN
american_scientific_journal-766	264	19	was	be	AUX
american_scientific_journal-766	264	20	required	require	VERB
american_scientific_journal-766	264	21	in	in	ADP
american_scientific_journal-766	264	22	patients	patient	NOUN
american_scientific_journal-766	264	23	with	with	ADP
american_scientific_journal-766	264	24	moderate	moderate	ADJ
american_scientific_journal-766	264	25	-	-	PUNCT
american_scientific_journal-766	264	26	to	to	ADP
american_scientific_journal-766	264	27	-	-	PUNCT
american_scientific_journal-766	264	28	severe	severe	ADJ
american_scientific_journal-766	264	29	hepatic	hepatic	ADJ
american_scientific_journal-766	264	30	impairment	impairment	NOUN
american_scientific_journal-766	264	31	[	[	X
american_scientific_journal-766	264	32	20	20	NUM
american_scientific_journal-766	264	33	]	]	PUNCT
american_scientific_journal-766	264	34	.	.	PUNCT
american_scientific_journal-766	265	1	safety	safety	NOUN
american_scientific_journal-766	265	2	profile	profile	NOUN
american_scientific_journal-766	265	3	did	do	AUX
american_scientific_journal-766	265	4	not	not	PART
american_scientific_journal-766	265	5	differ	differ	VERB
american_scientific_journal-766	265	6	in	in	ADP
american_scientific_journal-766	265	7	patients	patient	NOUN
american_scientific_journal-766	265	8	with	with	ADP
american_scientific_journal-766	265	9	well	well	ADV
american_scientific_journal-766	265	10	compensated	compensate	VERB
american_scientific_journal-766	265	11	liver	liver	NOUN
american_scientific_journal-766	265	12	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	265	13	who	who	PRON
american_scientific_journal-766	265	14	were	be	AUX
american_scientific_journal-766	265	15	included	include	VERB
american_scientific_journal-766	265	16	in	in	ADP
american_scientific_journal-766	265	17	the	the	DET
american_scientific_journal-766	265	18	phase	phase	NOUN
american_scientific_journal-766	265	19	iii	iii	NUM
american_scientific_journal-766	265	20	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	265	21	trials	trial	NOUN
american_scientific_journal-766	265	22	and	and	CCONJ
american_scientific_journal-766	265	23	no	no	DET
american_scientific_journal-766	265	24	hepatic	hepatic	ADJ
american_scientific_journal-766	265	25	decompensation	decompensation	NOUN
american_scientific_journal-766	265	26	was	be	AUX
american_scientific_journal-766	265	27	observed	observe	VERB
american_scientific_journal-766	265	28	while	while	SCONJ
american_scientific_journal-766	265	29	on	on	ADP
american_scientific_journal-766	265	30	any	any	PRON
american_scientific_journal-766	265	31	of	of	ADP
american_scientific_journal-766	265	32	the	the	DET
american_scientific_journal-766	265	33	ifnα	ifnα	NOUN
american_scientific_journal-766	265	34	-	-	PUNCT
american_scientific_journal-766	265	35	free	free	ADJ
american_scientific_journal-766	265	36	treatment	treatment	NOUN
american_scientific_journal-766	265	37	arms	arm	NOUN
american_scientific_journal-766	266	1	[	[	X
american_scientific_journal-766	266	2	81	81	NUM
american_scientific_journal-766	266	3	]	]	PUNCT
american_scientific_journal-766	266	4	.	.	PUNCT
american_scientific_journal-766	267	1	table	table	NOUN
american_scientific_journal-766	267	2	(	(	PUNCT
american_scientific_journal-766	267	3	2	2	NUM
american_scientific_journal-766	267	4	):	):	PUNCT
american_scientific_journal-766	267	5	different	different	ADJ
american_scientific_journal-766	267	6	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	267	7	efficacy	efficacy	PROPN
american_scientific_journal-766	267	8	studies	study	NOUN
american_scientific_journal-766	267	9	[	[	X
american_scientific_journal-766	267	10	72	72	NUM
american_scientific_journal-766	267	11	]	]	PUNCT
american_scientific_journal-766	267	12	.	.	PUNCT
american_scientific_journal-766	268	1	name	name	NOUN
american_scientific_journal-766	268	2	of	of	ADP
american_scientific_journal-766	268	3	study	study	NOUN
american_scientific_journal-766	268	4	design	design	NOUN
american_scientific_journal-766	268	5	genotype	genotype	NOUN
american_scientific_journal-766	268	6	svr	svr	PROPN
american_scientific_journal-766	268	7	(	(	PUNCT
american_scientific_journal-766	268	8	%	%	INTJ
american_scientific_journal-766	268	9	)	)	PUNCT
american_scientific_journal-766	268	10	proton	proton	NOUN
american_scientific_journal-766	268	11	sof	sof	NOUN
american_scientific_journal-766	268	12	,	,	PUNCT
american_scientific_journal-766	268	13	ifn	ifn	PROPN
american_scientific_journal-766	268	14	/	/	SYM
american_scientific_journal-766	268	15	rbv	rbv	NOUN
american_scientific_journal-766	268	16	1	1	NUM
american_scientific_journal-766	268	17	91	91	NUM
american_scientific_journal-766	268	18	atomic	atomic	ADJ
american_scientific_journal-766	268	19	sof	sof	NOUN
american_scientific_journal-766	268	20	,	,	PUNCT
american_scientific_journal-766	268	21	ifn	ifn	PROPN
american_scientific_journal-766	268	22	/	/	SYM
american_scientific_journal-766	268	23	rbv	rbv	NOUN
american_scientific_journal-766	268	24	1,4,6	1,4,6	NUM
american_scientific_journal-766	268	25	90–94	90–94	NUM
american_scientific_journal-766	268	26	neutrino	neutrino	NOUN
american_scientific_journal-766	268	27	sof	sof	VERB
american_scientific_journal-766	268	28	,	,	PUNCT
american_scientific_journal-766	268	29	ifn	ifn	PROPN
american_scientific_journal-766	268	30	/	/	SYM
american_scientific_journal-766	268	31	rbv	rbv	NOUN
american_scientific_journal-766	268	32	1,4,5,6	1,4,5,6	NUM
american_scientific_journal-766	268	33	89–100	89–100	NUM
american_scientific_journal-766	268	34	electron	electron	NOUN
american_scientific_journal-766	268	35	sof	sof	NOUN
american_scientific_journal-766	268	36	,	,	PUNCT
american_scientific_journal-766	268	37	rbv	rbv	VERB
american_scientific_journal-766	268	38	1	1	NUM
american_scientific_journal-766	268	39	88	88	NUM
american_scientific_journal-766	268	40	sof	sof	NOUN
american_scientific_journal-766	268	41	,	,	PUNCT
american_scientific_journal-766	268	42	rbv	rbv	PROPN
american_scientific_journal-766	268	43	,	,	PUNCT
american_scientific_journal-766	268	44	ledipasvir	ledipasvir	X
american_scientific_journal-766	268	45	100	100	NUM
american_scientific_journal-766	268	46	sof	sof	ADJ
american_scientific_journal-766	268	47	,	,	PUNCT
american_scientific_journal-766	268	48	rbv	rbv	NOUN
american_scientific_journal-766	268	49	,	,	PUNCT
american_scientific_journal-766	268	50	gs-9669	gs-9669	VERB
american_scientific_journal-766	268	51	92	92	NUM
american_scientific_journal-766	268	52	quantum	quantum	NOUN
american_scientific_journal-766	268	53	sof	sof	NOUN
american_scientific_journal-766	268	54	,	,	PUNCT
american_scientific_journal-766	268	55	rbv	rbv	VERB
american_scientific_journal-766	268	56	1	1	NUM
american_scientific_journal-766	268	57	56	56	NUM
american_scientific_journal-766	268	58	fission	fission	NOUN
american_scientific_journal-766	268	59	sof	sof	NOUN
american_scientific_journal-766	268	60	,	,	PUNCT
american_scientific_journal-766	268	61	rbv	rbv	VERB
american_scientific_journal-766	268	62	2,3	2,3	NUM
american_scientific_journal-766	268	63	67	67	NUM
american_scientific_journal-766	268	64	fusion	fusion	NOUN
american_scientific_journal-766	268	65	sof	sof	NOUN
american_scientific_journal-766	268	66	,	,	PUNCT
american_scientific_journal-766	268	67	rbv	rbv	VERB
american_scientific_journal-766	268	68	2,3	2,3	NUM
american_scientific_journal-766	268	69	56–73	56–73	NUM
american_scientific_journal-766	268	70	positron	positron	NOUN
american_scientific_journal-766	268	71	sof	sof	VERB
american_scientific_journal-766	268	72	,	,	PUNCT
american_scientific_journal-766	268	73	rbv	rbv	VERB
american_scientific_journal-766	268	74	2,3	2,3	NUM
american_scientific_journal-766	268	75	61–93	61–93	NUM
american_scientific_journal-766	268	76	lonestar	lonestar	NOUN
american_scientific_journal-766	268	77	sof	sof	PROPN
american_scientific_journal-766	268	78	,	,	PUNCT
american_scientific_journal-766	268	79	rbv	rbv	PROPN
american_scientific_journal-766	268	80	,	,	PUNCT
american_scientific_journal-766	268	81	ledipasvir	ledipasvir	X
american_scientific_journal-766	268	82	1	1	NUM
american_scientific_journal-766	268	83	95–100	95–100	NUM
american_scientific_journal-766	268	84	2.2.5.3	2.2.5.3	NUM
american_scientific_journal-766	268	85	.	.	PUNCT
american_scientific_journal-766	268	86	potential	potential	NOUN
american_scientific_journal-766	268	87	for	for	ADP
american_scientific_journal-766	268	88	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	268	89	in	in	ADP
american_scientific_journal-766	268	90	liver	liver	NOUN
american_scientific_journal-766	268	91	transplantation	transplantation	NOUN
american_scientific_journal-766	268	92	one	one	NUM
american_scientific_journal-766	268	93	obvious	obvious	ADJ
american_scientific_journal-766	268	94	clinical	clinical	ADJ
american_scientific_journal-766	268	95	need	need	NOUN
american_scientific_journal-766	268	96	is	be	AUX
american_scientific_journal-766	268	97	for	for	ADP
american_scientific_journal-766	268	98	data	datum	NOUN
american_scientific_journal-766	268	99	regarding	regard	VERB
american_scientific_journal-766	268	100	safety	safety	NOUN
american_scientific_journal-766	268	101	and	and	CCONJ
american_scientific_journal-766	268	102	efficacy	efficacy	NOUN
american_scientific_journal-766	268	103	of	of	ADP
american_scientific_journal-766	268	104	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	268	105	in	in	ADP
american_scientific_journal-766	268	106	patients	patient	NOUN
american_scientific_journal-766	268	107	who	who	PRON
american_scientific_journal-766	268	108	have	have	AUX
american_scientific_journal-766	268	109	decompensated	decompensate	VERB
american_scientific_journal-766	268	110	chronic	chronic	ADJ
american_scientific_journal-766	268	111	liver	liver	NOUN
american_scientific_journal-766	268	112	disease	disease	NOUN
american_scientific_journal-766	268	113	,	,	PUNCT
american_scientific_journal-766	268	114	are	be	AUX
american_scientific_journal-766	268	115	peri	peri	NOUN
american_scientific_journal-766	268	116	-	-	PUNCT
american_scientific_journal-766	268	117	transplant	transplant	NOUN
american_scientific_journal-766	268	118	or	or	CCONJ
american_scientific_journal-766	268	119	post	post	ADJ
american_scientific_journal-766	268	120	-	-	ADJ
american_scientific_journal-766	268	121	liver	liver	ADJ
american_scientific_journal-766	268	122	-	-	PUNCT
american_scientific_journal-766	268	123	transplant	transplant	NOUN
american_scientific_journal-766	268	124	.	.	PUNCT
american_scientific_journal-766	269	1	the	the	DET
american_scientific_journal-766	269	2	excellent	excellent	ADJ
american_scientific_journal-766	269	3	safety	safety	NOUN
american_scientific_journal-766	269	4	data	datum	NOUN
american_scientific_journal-766	269	5	to	to	ADP
american_scientific_journal-766	269	6	14	14	NUM
american_scientific_journal-766	269	7	american	american	ADJ
american_scientific_journal-766	269	8	scientific	scientific	ADJ
american_scientific_journal-766	269	9	research	research	NOUN
american_scientific_journal-766	269	10	journal	journal	NOUN
american_scientific_journal-766	269	11	for	for	ADP
american_scientific_journal-766	269	12	engineering	engineering	NOUN
american_scientific_journal-766	269	13	,	,	PUNCT
american_scientific_journal-766	269	14	technology	technology	NOUN
american_scientific_journal-766	269	15	,	,	PUNCT
american_scientific_journal-766	269	16	and	and	CCONJ
american_scientific_journal-766	269	17	sciences	science	NOUN
american_scientific_journal-766	269	18	(	(	PUNCT
american_scientific_journal-766	269	19	asrjets	asrjet	NOUN
american_scientific_journal-766	269	20	)	)	PUNCT
american_scientific_journal-766	269	21	(	(	PUNCT
american_scientific_journal-766	269	22	2015	2015	NUM
american_scientific_journal-766	269	23	)	)	PUNCT
american_scientific_journal-766	269	24	volume	volume	NOUN
american_scientific_journal-766	269	25	13	13	NUM
american_scientific_journal-766	269	26	,	,	PUNCT
american_scientific_journal-766	269	27	no	no	DET
american_scientific_journal-766	269	28	1	1	NUM
american_scientific_journal-766	269	29	,	,	PUNCT
american_scientific_journal-766	269	30	pp	pp	ADV
american_scientific_journal-766	269	31	1	1	NUM
american_scientific_journal-766	269	32	-	-	SYM
american_scientific_journal-766	269	33	23	23	NUM
american_scientific_journal-766	269	34	date	date	NOUN
american_scientific_journal-766	269	35	and	and	CCONJ
american_scientific_journal-766	269	36	the	the	DET
american_scientific_journal-766	269	37	lack	lack	NOUN
american_scientific_journal-766	269	38	of	of	ADP
american_scientific_journal-766	269	39	significant	significant	ADJ
american_scientific_journal-766	269	40	drug	drug	NOUN
american_scientific_journal-766	269	41	interactions	interaction	NOUN
american_scientific_journal-766	269	42	makes	make	VERB
american_scientific_journal-766	269	43	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	269	44	an	an	DET
american_scientific_journal-766	269	45	appealing	appealing	ADJ
american_scientific_journal-766	269	46	choice	choice	NOUN
american_scientific_journal-766	269	47	to	to	PART
american_scientific_journal-766	269	48	be	be	AUX
american_scientific_journal-766	269	49	studied	study	VERB
american_scientific_journal-766	269	50	in	in	ADP
american_scientific_journal-766	269	51	these	these	DET
american_scientific_journal-766	269	52	groups	group	NOUN
american_scientific_journal-766	269	53	.	.	PUNCT
american_scientific_journal-766	270	1	to	to	ADP
american_scientific_journal-766	270	2	date	date	NOUN
american_scientific_journal-766	270	3	there	there	PRON
american_scientific_journal-766	270	4	is	be	VERB
american_scientific_journal-766	270	5	one	one	NUM
american_scientific_journal-766	270	6	case	case	NOUN
american_scientific_journal-766	270	7	report	report	NOUN
american_scientific_journal-766	270	8	published	publish	VERB
american_scientific_journal-766	270	9	of	of	ADP
american_scientific_journal-766	270	10	a	a	DET
american_scientific_journal-766	270	11	patient	patient	NOUN
american_scientific_journal-766	270	12	with	with	ADP
american_scientific_journal-766	270	13	severe	severe	ADJ
american_scientific_journal-766	270	14	recurrent	recurrent	ADJ
american_scientific_journal-766	270	15	cholestatic	cholestatic	ADJ
american_scientific_journal-766	270	16	hepatitis	hepatitis	PROPN
american_scientific_journal-766	270	17	c	c	NOUN
american_scientific_journal-766	270	18	,	,	PUNCT
american_scientific_journal-766	270	19	6	6	NUM
american_scientific_journal-766	270	20	months	month	NOUN
american_scientific_journal-766	270	21	post	post	ADJ
american_scientific_journal-766	270	22	-	-	NOUN
american_scientific_journal-766	270	23	transplant	transplant	ADJ
american_scientific_journal-766	270	24	,	,	PUNCT
american_scientific_journal-766	270	25	who	who	PRON
american_scientific_journal-766	270	26	was	be	AUX
american_scientific_journal-766	270	27	effectively	effectively	ADV
american_scientific_journal-766	270	28	rescued	rescue	VERB
american_scientific_journal-766	270	29	and	and	CCONJ
american_scientific_journal-766	270	30	achieved	achieve	VERB
american_scientific_journal-766	270	31	svr	svr	PROPN
american_scientific_journal-766	270	32	with	with	ADP
american_scientific_journal-766	270	33	treatment	treatment	NOUN
american_scientific_journal-766	270	34	with	with	ADP
american_scientific_journal-766	270	35	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	270	36	and	and	CCONJ
american_scientific_journal-766	270	37	daclatasvir	daclatasvir	PROPN
american_scientific_journal-766	270	38	in	in	ADP
american_scientific_journal-766	270	39	combination	combination	NOUN
american_scientific_journal-766	270	40	[	[	X
american_scientific_journal-766	270	41	83	83	NUM
american_scientific_journal-766	270	42	]	]	PUNCT
american_scientific_journal-766	270	43	.	.	PUNCT
american_scientific_journal-766	271	1	this	this	PRON
american_scientific_journal-766	271	2	is	be	AUX
american_scientific_journal-766	271	3	promising	promise	VERB
american_scientific_journal-766	271	4	,	,	PUNCT
american_scientific_journal-766	271	5	and	and	CCONJ
american_scientific_journal-766	271	6	results	result	NOUN
american_scientific_journal-766	271	7	of	of	ADP
american_scientific_journal-766	271	8	future	future	ADJ
american_scientific_journal-766	271	9	trials	trial	NOUN
american_scientific_journal-766	271	10	of	of	ADP
american_scientific_journal-766	271	11	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	271	12	in	in	ADP
american_scientific_journal-766	271	13	these	these	DET
american_scientific_journal-766	271	14	types	type	NOUN
american_scientific_journal-766	271	15	of	of	ADP
american_scientific_journal-766	271	16	patient	patient	ADJ
american_scientific_journal-766	271	17	groups	group	NOUN
american_scientific_journal-766	271	18	are	be	AUX
american_scientific_journal-766	271	19	awaited	await	VERB
american_scientific_journal-766	271	20	with	with	ADP
american_scientific_journal-766	271	21	interest	interest	NOUN
american_scientific_journal-766	271	22	.	.	PUNCT
american_scientific_journal-766	272	1	moreover	moreover	ADV
american_scientific_journal-766	272	2	,	,	PUNCT
american_scientific_journal-766	272	3	[	[	X
american_scientific_journal-766	272	4	66	66	NUM
american_scientific_journal-766	272	5	]	]	PUNCT
american_scientific_journal-766	272	6	reported	report	VERB
american_scientific_journal-766	272	7	that	that	SCONJ
american_scientific_journal-766	272	8	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	272	9	and	and	CCONJ
american_scientific_journal-766	272	10	ribavirin	ribavirin	NOUN
american_scientific_journal-766	272	11	combination	combination	NOUN
american_scientific_journal-766	272	12	therapy	therapy	NOUN
american_scientific_journal-766	272	13	for	for	ADP
american_scientific_journal-766	272	14	24	24	NUM
american_scientific_journal-766	272	15	weeks	week	NOUN
american_scientific_journal-766	272	16	is	be	AUX
american_scientific_journal-766	272	17	an	an	DET
american_scientific_journal-766	272	18	effective	effective	ADJ
american_scientific_journal-766	272	19	and	and	CCONJ
american_scientific_journal-766	272	20	well	well	ADV
american_scientific_journal-766	272	21	-	-	PUNCT
american_scientific_journal-766	272	22	tolerated	tolerate	VERB
american_scientific_journal-766	272	23	interferon	interferon	ADJ
american_scientific_journal-766	272	24	-	-	PUNCT
american_scientific_journal-766	272	25	free	free	ADJ
american_scientific_journal-766	272	26	treatment	treatment	NOUN
american_scientific_journal-766	272	27	for	for	ADP
american_scientific_journal-766	272	28	post	post	ADJ
american_scientific_journal-766	272	29	-	-	ADJ
american_scientific_journal-766	272	30	transplantation	transplantation	ADJ
american_scientific_journal-766	272	31	hcv	hcv	NOUN
american_scientific_journal-766	272	32	infection	infection	NOUN
american_scientific_journal-766	272	33	.	.	PUNCT
american_scientific_journal-766	273	1	2.2.5.4	2.2.5.4	X
american_scientific_journal-766	273	2	.	.	X
american_scientific_journal-766	273	3	resistance	resistance	NOUN
american_scientific_journal-766	273	4	to	to	PART
american_scientific_journal-766	273	5	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	273	6	sof	sof	PROPN
american_scientific_journal-766	273	7	has	have	AUX
american_scientific_journal-766	273	8	been	be	AUX
american_scientific_journal-766	273	9	studied	study	VERB
american_scientific_journal-766	273	10	in	in	ADP
american_scientific_journal-766	273	11	several	several	ADJ
american_scientific_journal-766	273	12	thousand	thousand	NUM
american_scientific_journal-766	273	13	patients	patient	NOUN
american_scientific_journal-766	273	14	to	to	ADP
american_scientific_journal-766	273	15	date	date	NOUN
american_scientific_journal-766	273	16	,	,	PUNCT
american_scientific_journal-766	273	17	and	and	CCONJ
american_scientific_journal-766	273	18	effective	effective	ADJ
american_scientific_journal-766	273	19	in	in	ADP
american_scientific_journal-766	273	20	vivo	vivo	ADJ
american_scientific_journal-766	273	21	drug	drug	NOUN
american_scientific_journal-766	273	22	resistance	resistance	NOUN
american_scientific_journal-766	273	23	leading	lead	VERB
american_scientific_journal-766	273	24	to	to	ADP
american_scientific_journal-766	273	25	viral	viral	ADJ
american_scientific_journal-766	273	26	escape	escape	NOUN
american_scientific_journal-766	273	27	and	and	CCONJ
american_scientific_journal-766	273	28	relapse	relapse	VERB
american_scientific_journal-766	273	29	in	in	ADP
american_scientific_journal-766	273	30	response	response	NOUN
american_scientific_journal-766	273	31	to	to	ADP
american_scientific_journal-766	273	32	therapy	therapy	NOUN
american_scientific_journal-766	273	33	appears	appear	VERB
american_scientific_journal-766	273	34	to	to	PART
american_scientific_journal-766	273	35	be	be	AUX
american_scientific_journal-766	273	36	,	,	PUNCT
american_scientific_journal-766	273	37	at	at	ADP
american_scientific_journal-766	273	38	best	well	ADV
american_scientific_journal-766	273	39	,	,	PUNCT
american_scientific_journal-766	273	40	a	a	DET
american_scientific_journal-766	273	41	rare	rare	ADJ
american_scientific_journal-766	273	42	event	event	NOUN
american_scientific_journal-766	273	43	.	.	PUNCT
american_scientific_journal-766	274	1	in	in	ADP
american_scientific_journal-766	274	2	the	the	DET
american_scientific_journal-766	274	3	registration	registration	NOUN
american_scientific_journal-766	274	4	phase	phase	NOUN
american_scientific_journal-766	274	5	iii	iii	NUM
american_scientific_journal-766	274	6	studies	study	NOUN
american_scientific_journal-766	274	7	,	,	PUNCT
american_scientific_journal-766	274	8	no	no	DET
american_scientific_journal-766	274	9	genotypic	genotypic	NOUN
american_scientific_journal-766	274	10	or	or	CCONJ
american_scientific_journal-766	274	11	phenotypic	phenotypic	ADJ
american_scientific_journal-766	274	12	resistance	resistance	NOUN
american_scientific_journal-766	274	13	was	be	AUX
american_scientific_journal-766	274	14	detected	detect	VERB
american_scientific_journal-766	274	15	.	.	PUNCT
american_scientific_journal-766	275	1	in	in	ADP
american_scientific_journal-766	275	2	phase	phase	NOUN
american_scientific_journal-766	275	3	ii	ii	PROPN
american_scientific_journal-766	275	4	trials	trial	NOUN
american_scientific_journal-766	275	5	,	,	PUNCT
american_scientific_journal-766	275	6	s282	s282	PROPN
american_scientific_journal-766	275	7	t	t	NOUN
american_scientific_journal-766	275	8	mutation	mutation	NOUN
american_scientific_journal-766	275	9	was	be	AUX
american_scientific_journal-766	275	10	detected	detect	VERB
american_scientific_journal-766	275	11	in	in	ADP
american_scientific_journal-766	275	12	only	only	ADV
american_scientific_journal-766	275	13	one	one	NUM
american_scientific_journal-766	275	14	relapse	relapse	NOUN
american_scientific_journal-766	275	15	patient	patient	NOUN
american_scientific_journal-766	275	16	,	,	PUNCT
american_scientific_journal-766	275	17	and	and	CCONJ
american_scientific_journal-766	275	18	this	this	PRON
american_scientific_journal-766	275	19	occurred	occur	VERB
american_scientific_journal-766	275	20	after	after	SCONJ
american_scientific_journal-766	275	21	sof	sof	VERB
american_scientific_journal-766	275	22	monotherapy	monotherapy	NOUN
american_scientific_journal-766	275	23	[	[	X
american_scientific_journal-766	275	24	75	75	NUM
american_scientific_journal-766	275	25	]	]	PUNCT
american_scientific_journal-766	275	26	.	.	PUNCT
american_scientific_journal-766	276	1	overall	overall	ADV
american_scientific_journal-766	276	2	,	,	PUNCT
american_scientific_journal-766	276	3	sof	sof	PROPN
american_scientific_journal-766	276	4	has	have	AUX
american_scientific_journal-766	276	5	eliminated	eliminate	VERB
american_scientific_journal-766	276	6	most	most	ADJ
american_scientific_journal-766	276	7	of	of	ADP
american_scientific_journal-766	276	8	the	the	DET
american_scientific_journal-766	276	9	treatment	treatment	NOUN
american_scientific_journal-766	276	10	barriers	barrier	NOUN
american_scientific_journal-766	276	11	for	for	ADP
american_scientific_journal-766	276	12	patients	patient	NOUN
american_scientific_journal-766	276	13	that	that	PRON
american_scientific_journal-766	276	14	were	be	AUX
american_scientific_journal-766	276	15	present	present	ADJ
american_scientific_journal-766	276	16	in	in	ADP
american_scientific_journal-766	276	17	the	the	DET
american_scientific_journal-766	276	18	ifn	ifn	PROPN
american_scientific_journal-766	276	19	era	era	NOUN
american_scientific_journal-766	276	20	.	.	PUNCT
american_scientific_journal-766	277	1	nevertheless	nevertheless	ADV
american_scientific_journal-766	277	2	,	,	PUNCT
american_scientific_journal-766	277	3	making	make	VERB
american_scientific_journal-766	277	4	treatment	treatment	NOUN
american_scientific_journal-766	277	5	decisions	decision	NOUN
american_scientific_journal-766	277	6	among	among	ADP
american_scientific_journal-766	277	7	patients	patient	NOUN
american_scientific_journal-766	277	8	still	still	ADV
american_scientific_journal-766	277	9	requires	require	VERB
american_scientific_journal-766	277	10	thoughtful	thoughtful	ADJ
american_scientific_journal-766	277	11	consideration	consideration	NOUN
american_scientific_journal-766	277	12	,	,	PUNCT
american_scientific_journal-766	277	13	as	as	SCONJ
american_scientific_journal-766	277	14	host	host	NOUN
american_scientific_journal-766	277	15	factors	factor	NOUN
american_scientific_journal-766	277	16	such	such	ADJ
american_scientific_journal-766	277	17	as	as	ADP
american_scientific_journal-766	277	18	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	277	19	and	and	CCONJ
american_scientific_journal-766	277	20	viral	viral	ADJ
american_scientific_journal-766	277	21	factors	factor	NOUN
american_scientific_journal-766	277	22	such	such	ADJ
american_scientific_journal-766	277	23	as	as	ADP
american_scientific_journal-766	277	24	genotype	genotype	NOUN
american_scientific_journal-766	277	25	still	still	ADV
american_scientific_journal-766	277	26	have	have	VERB
american_scientific_journal-766	277	27	significant	significant	ADJ
american_scientific_journal-766	277	28	influences	influence	NOUN
american_scientific_journal-766	277	29	on	on	ADP
american_scientific_journal-766	277	30	treatment	treatment	NOUN
american_scientific_journal-766	277	31	times	time	NOUN
american_scientific_journal-766	277	32	and	and	CCONJ
american_scientific_journal-766	277	33	,	,	PUNCT
american_scientific_journal-766	277	34	in	in	ADP
american_scientific_journal-766	277	35	some	some	DET
american_scientific_journal-766	277	36	cases	case	NOUN
american_scientific_journal-766	277	37	,	,	PUNCT
american_scientific_journal-766	277	38	outcome	outcome	NOUN
american_scientific_journal-766	277	39	.	.	PUNCT
american_scientific_journal-766	278	1	an	an	DET
american_scientific_journal-766	278	2	important	important	ADJ
american_scientific_journal-766	278	3	principle	principle	NOUN
american_scientific_journal-766	278	4	is	be	AUX
american_scientific_journal-766	278	5	that	that	SCONJ
american_scientific_journal-766	278	6	monotherapy	monotherapy	NOUN
american_scientific_journal-766	278	7	with	with	ADP
american_scientific_journal-766	278	8	sof	sof	PROPN
american_scientific_journal-766	278	9	is	be	AUX
american_scientific_journal-766	278	10	not	not	PART
american_scientific_journal-766	278	11	recommended	recommend	VERB
american_scientific_journal-766	278	12	[	[	PUNCT
american_scientific_journal-766	278	13	34	34	NUM
american_scientific_journal-766	278	14	]	]	PUNCT
american_scientific_journal-766	278	15	.	.	PUNCT
american_scientific_journal-766	279	1	cross	cross	ADJ
american_scientific_journal-766	279	2	-	-	ADJ
american_scientific_journal-766	279	3	resistance	resistance	ADJ
american_scientific_journal-766	279	4	studies	study	NOUN
american_scientific_journal-766	279	5	have	have	AUX
american_scientific_journal-766	279	6	been	be	AUX
american_scientific_journal-766	279	7	conducted	conduct	VERB
american_scientific_journal-766	279	8	using	use	VERB
american_scientific_journal-766	279	9	panels	panel	NOUN
american_scientific_journal-766	279	10	of	of	ADP
american_scientific_journal-766	279	11	replicons	replicon	NOUN
american_scientific_journal-766	279	12	with	with	ADP
american_scientific_journal-766	279	13	mutations	mutation	NOUN
american_scientific_journal-766	279	14	in	in	ADP
american_scientific_journal-766	279	15	the	the	DET
american_scientific_journal-766	279	16	ns3/4a	ns3/4a	NUM
american_scientific_journal-766	279	17	protease	protease	NOUN
american_scientific_journal-766	279	18	,	,	PUNCT
american_scientific_journal-766	279	19	ns5a	ns5a	NOUN
american_scientific_journal-766	279	20	,	,	PUNCT
american_scientific_journal-766	279	21	and	and	CCONJ
american_scientific_journal-766	279	22	ns5b	ns5b	PROPN
american_scientific_journal-766	279	23	,	,	PUNCT
american_scientific_journal-766	279	24	which	which	PRON
american_scientific_journal-766	279	25	remained	remain	VERB
american_scientific_journal-766	279	26	susceptible	susceptible	ADJ
american_scientific_journal-766	279	27	to	to	ADP
american_scientific_journal-766	279	28	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	279	29	(	(	PUNCT
american_scientific_journal-766	279	30	except	except	SCONJ
american_scientific_journal-766	279	31	for	for	ADP
american_scientific_journal-766	279	32	hcv	hcv	NOUN
american_scientific_journal-766	279	33	type	type	NOUN
american_scientific_journal-766	279	34	1b	1b	PROPN
american_scientific_journal-766	279	35	s282	s282	PROPN
american_scientific_journal-766	279	36	t	t	PROPN
american_scientific_journal-766	279	37	)	)	PUNCT
american_scientific_journal-766	279	38	,	,	PUNCT
american_scientific_journal-766	279	39	thus	thus	ADV
american_scientific_journal-766	279	40	indicating	indicate	VERB
american_scientific_journal-766	279	41	that	that	SCONJ
american_scientific_journal-766	279	42	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	279	43	can	can	AUX
american_scientific_journal-766	279	44	be	be	AUX
american_scientific_journal-766	279	45	combined	combine	VERB
american_scientific_journal-766	279	46	with	with	ADP
american_scientific_journal-766	279	47	other	other	ADJ
american_scientific_journal-766	279	48	directly	directly	ADV
american_scientific_journal-766	279	49	acting	act	VERB
american_scientific_journal-766	279	50	antiviral	antiviral	ADJ
american_scientific_journal-766	279	51	agents	agent	NOUN
american_scientific_journal-766	279	52	.	.	PUNCT
american_scientific_journal-766	280	1	it	it	PRON
american_scientific_journal-766	280	2	has	have	AUX
american_scientific_journal-766	280	3	been	be	AUX
american_scientific_journal-766	280	4	suggested	suggest	VERB
american_scientific_journal-766	280	5	that	that	SCONJ
american_scientific_journal-766	280	6	additional	additional	ADJ
american_scientific_journal-766	280	7	mutations	mutation	NOUN
american_scientific_journal-766	280	8	with	with	ADP
american_scientific_journal-766	280	9	amino	amino	ADJ
american_scientific_journal-766	280	10	acids	acid	NOUN
american_scientific_journal-766	280	11	change	change	NOUN
american_scientific_journal-766	280	12	in	in	ADP
american_scientific_journal-766	280	13	both	both	CCONJ
american_scientific_journal-766	280	14	the	the	DET
american_scientific_journal-766	280	15	finger	finger	NOUN
american_scientific_journal-766	280	16	and	and	CCONJ
american_scientific_journal-766	280	17	palm	palm	NOUN
american_scientific_journal-766	280	18	domains	domain	NOUN
american_scientific_journal-766	280	19	and	and	CCONJ
american_scientific_journal-766	280	20	are	be	AUX
american_scientific_journal-766	280	21	required	require	VERB
american_scientific_journal-766	280	22	to	to	PART
american_scientific_journal-766	280	23	compensate	compensate	VERB
american_scientific_journal-766	280	24	for	for	ADP
american_scientific_journal-766	280	25	poor	poor	ADJ
american_scientific_journal-766	280	26	hcv	hcv	PROPN
american_scientific_journal-766	280	27	fitness	fitness	NOUN
american_scientific_journal-766	280	28	,	,	PUNCT
american_scientific_journal-766	280	29	resulting	result	VERB
american_scientific_journal-766	280	30	from	from	ADP
american_scientific_journal-766	280	31	s282	s282	PROPN
american_scientific_journal-766	280	32	t	t	NOUN
american_scientific_journal-766	280	33	mutation	mutation	NOUN
american_scientific_journal-766	280	34	,	,	PUNCT
american_scientific_journal-766	280	35	in	in	ADP
american_scientific_journal-766	280	36	order	order	NOUN
american_scientific_journal-766	280	37	to	to	PART
american_scientific_journal-766	280	38	confer	confer	VERB
american_scientific_journal-766	280	39	resistance	resistance	NOUN
american_scientific_journal-766	280	40	to	to	ADP
american_scientific_journal-766	280	41	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	281	1	[	[	X
american_scientific_journal-766	281	2	20	20	NUM
american_scientific_journal-766	281	3	]	]	PUNCT
american_scientific_journal-766	281	4	.	.	PUNCT
american_scientific_journal-766	282	1	the	the	DET
american_scientific_journal-766	282	2	s282	s282	PROPN
american_scientific_journal-766	282	3	t	t	NOUN
american_scientific_journal-766	282	4	mutation	mutation	NOUN
american_scientific_journal-766	282	5	has	have	AUX
american_scientific_journal-766	282	6	so	so	ADV
american_scientific_journal-766	282	7	far	far	ADV
american_scientific_journal-766	282	8	only	only	ADV
american_scientific_journal-766	282	9	been	be	AUX
american_scientific_journal-766	282	10	detected	detect	VERB
american_scientific_journal-766	282	11	in	in	ADP
american_scientific_journal-766	282	12	one	one	NUM
american_scientific_journal-766	282	13	patient	patient	NOUN
american_scientific_journal-766	282	14	,	,	PUNCT
american_scientific_journal-766	282	15	with	with	ADP
american_scientific_journal-766	282	16	hcv	hcv	NOUN
american_scientific_journal-766	282	17	type	type	NOUN
american_scientific_journal-766	282	18	2b	2b	NOUN
american_scientific_journal-766	282	19	;	;	PUNCT
american_scientific_journal-766	282	20	a	a	DET
american_scientific_journal-766	282	21	relapse	relapse	NOUN
american_scientific_journal-766	282	22	has	have	AUX
american_scientific_journal-766	282	23	been	be	AUX
american_scientific_journal-766	282	24	seen	see	VERB
american_scientific_journal-766	282	25	in	in	ADP
american_scientific_journal-766	282	26	this	this	DET
american_scientific_journal-766	282	27	patient	patient	NOUN
american_scientific_journal-766	282	28	after	after	ADP
american_scientific_journal-766	282	29	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	282	30	monotherapy	monotherapy	NOUN
american_scientific_journal-766	282	31	.	.	PUNCT
american_scientific_journal-766	283	1	genotype	genotype	NOUN
american_scientific_journal-766	283	2	or	or	CCONJ
american_scientific_journal-766	283	3	subtype	subtype	NOUN
american_scientific_journal-766	283	4	-	-	PUNCT
american_scientific_journal-766	283	5	specific	specific	ADJ
american_scientific_journal-766	283	6	resistance	resistance	NOUN
american_scientific_journal-766	283	7	has	have	AUX
american_scientific_journal-766	283	8	not	not	PART
american_scientific_journal-766	283	9	been	be	AUX
american_scientific_journal-766	283	10	seen	see	VERB
american_scientific_journal-766	283	11	with	with	ADP
american_scientific_journal-766	283	12	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	283	13	[	[	X
american_scientific_journal-766	283	14	92	92	NUM
american_scientific_journal-766	283	15	]	]	PUNCT
american_scientific_journal-766	283	16	.	.	PUNCT
american_scientific_journal-766	284	1	in	in	ADP
american_scientific_journal-766	284	2	the	the	DET
american_scientific_journal-766	284	3	clinical	clinical	ADJ
american_scientific_journal-766	284	4	studies	study	NOUN
american_scientific_journal-766	284	5	,	,	PUNCT
american_scientific_journal-766	284	6	although	although	SCONJ
american_scientific_journal-766	284	7	relapse	relapse	NOUN
american_scientific_journal-766	284	8	leading	lead	VERB
american_scientific_journal-766	284	9	to	to	ADP
american_scientific_journal-766	284	10	treatment	treatment	NOUN
american_scientific_journal-766	284	11	failure	failure	NOUN
american_scientific_journal-766	284	12	was	be	AUX
american_scientific_journal-766	284	13	seen	see	VERB
american_scientific_journal-766	284	14	in	in	ADP
american_scientific_journal-766	284	15	a	a	DET
american_scientific_journal-766	284	16	few	few	ADJ
american_scientific_journal-766	284	17	patients	patient	NOUN
american_scientific_journal-766	284	18	,	,	PUNCT
american_scientific_journal-766	284	19	no	no	DET
american_scientific_journal-766	284	20	virological	virological	ADJ
american_scientific_journal-766	284	21	resistance	resistance	NOUN
american_scientific_journal-766	284	22	was	be	AUX
american_scientific_journal-766	284	23	detected	detect	VERB
american_scientific_journal-766	284	24	in	in	ADP
american_scientific_journal-766	284	25	these	these	DET
american_scientific_journal-766	284	26	patients	patient	NOUN
american_scientific_journal-766	284	27	receiving	receive	VERB
american_scientific_journal-766	284	28	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	284	29	400	400	NUM
american_scientific_journal-766	284	30	mg	mg	NOUN
american_scientific_journal-766	284	31	monotherapy	monotherapy	NOUN
american_scientific_journal-766	284	32	or	or	CCONJ
american_scientific_journal-766	284	33	in	in	ADP
american_scientific_journal-766	284	34	combination	combination	NOUN
american_scientific_journal-766	284	35	with	with	ADP
american_scientific_journal-766	284	36	ribavirin	ribavirin	NOUN
american_scientific_journal-766	284	37	,	,	PUNCT
american_scientific_journal-766	284	38	peg	peg	NOUN
american_scientific_journal-766	284	39	-	-	PUNCT
american_scientific_journal-766	284	40	inf	inf	NOUN
american_scientific_journal-766	284	41	or	or	CCONJ
american_scientific_journal-766	284	42	both	both	PRON
american_scientific_journal-766	284	43	[	[	X
american_scientific_journal-766	284	44	84	84	NUM
american_scientific_journal-766	284	45	]	]	PUNCT
american_scientific_journal-766	284	46	.	.	PUNCT
american_scientific_journal-766	285	1	2.2.5.5	2.2.5.5	X
american_scientific_journal-766	285	2	.	.	PUNCT
american_scientific_journal-766	285	3	adverse	adverse	ADJ
american_scientific_journal-766	285	4	events	event	NOUN
american_scientific_journal-766	285	5	of	of	ADP
american_scientific_journal-766	285	6	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	285	7	adverse	adverse	ADJ
american_scientific_journal-766	285	8	events	event	NOUN
american_scientific_journal-766	285	9	associated	associate	VERB
american_scientific_journal-766	285	10	with	with	ADP
american_scientific_journal-766	285	11	ribavirin	ribavirin	NOUN
american_scientific_journal-766	285	12	therapy	therapy	NOUN
american_scientific_journal-766	285	13	(	(	PUNCT
american_scientific_journal-766	285	14	fatigue	fatigue	NOUN
american_scientific_journal-766	285	15	,	,	PUNCT
american_scientific_journal-766	285	16	insomnia	insomnia	NOUN
american_scientific_journal-766	285	17	and	and	CCONJ
american_scientific_journal-766	285	18	anemia	anemia	NOUN
american_scientific_journal-766	285	19	)	)	PUNCT
american_scientific_journal-766	285	20	were	be	AUX
american_scientific_journal-766	285	21	commonly	commonly	ADV
american_scientific_journal-766	285	22	reported	report	VERB
american_scientific_journal-766	285	23	,	,	PUNCT
american_scientific_journal-766	285	24	and	and	CCONJ
american_scientific_journal-766	285	25	headache	headache	NOUN
american_scientific_journal-766	285	26	was	be	AUX
american_scientific_journal-766	285	27	also	also	ADV
american_scientific_journal-766	285	28	frequently	frequently	ADV
american_scientific_journal-766	285	29	reported	report	VERB
american_scientific_journal-766	285	30	.	.	PUNCT
american_scientific_journal-766	286	1	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	286	2	has	have	AUX
american_scientific_journal-766	286	3	shown	show	VERB
american_scientific_journal-766	286	4	a	a	DET
american_scientific_journal-766	286	5	good	good	ADJ
american_scientific_journal-766	286	6	safety	safety	NOUN
american_scientific_journal-766	286	7	profile	profile	NOUN
american_scientific_journal-766	286	8	in	in	ADP
american_scientific_journal-766	286	9	clinical	clinical	ADJ
american_scientific_journal-766	286	10	trials	trial	NOUN
american_scientific_journal-766	286	11	;	;	PUNCT
american_scientific_journal-766	286	12	a	a	DET
american_scientific_journal-766	286	13	small	small	ADJ
american_scientific_journal-766	286	14	decrease	decrease	NOUN
american_scientific_journal-766	286	15	in	in	ADP
american_scientific_journal-766	286	16	the	the	DET
american_scientific_journal-766	286	17	hb	hb	PROPN
american_scientific_journal-766	286	18	levels	level	NOUN
american_scientific_journal-766	286	19	(	(	PUNCT
american_scientific_journal-766	286	20	0.54	0.54	NUM
american_scientific_journal-766	286	21	mg	mg	PROPN
american_scientific_journal-766	286	22	/	/	SYM
american_scientific_journal-766	286	23	dl	dl	NOUN
american_scientific_journal-766	286	24	)	)	PUNCT
american_scientific_journal-766	286	25	and	and	CCONJ
american_scientific_journal-766	286	26	reduction	reduction	NOUN
american_scientific_journal-766	286	27	in	in	ADP
american_scientific_journal-766	286	28	the	the	DET
american_scientific_journal-766	286	29	cumulative	cumulative	ADJ
american_scientific_journal-766	286	30	events	event	NOUN
american_scientific_journal-766	286	31	in	in	ADP
american_scientific_journal-766	286	32	comparison	comparison	NOUN
american_scientific_journal-766	286	33	to	to	ADP
american_scientific_journal-766	286	34	interferoncontaining	interferoncontaine	VERB
american_scientific_journal-766	286	35	regimens	regimen	NOUN
american_scientific_journal-766	286	36	is	be	AUX
american_scientific_journal-766	286	37	seen	see	VERB
american_scientific_journal-766	286	38	.	.	PUNCT
american_scientific_journal-766	287	1	common	common	ADJ
american_scientific_journal-766	287	2	adverse	adverse	ADJ
american_scientific_journal-766	287	3	events	event	NOUN
american_scientific_journal-766	287	4	observed	observe	VERB
american_scientific_journal-766	287	5	include	include	VERB
american_scientific_journal-766	287	6	:	:	PUNCT
american_scientific_journal-766	287	7	headache	headache	NOUN
american_scientific_journal-766	287	8	,	,	PUNCT
american_scientific_journal-766	287	9	insomnia	insomnia	NOUN
american_scientific_journal-766	287	10	,	,	PUNCT
american_scientific_journal-766	287	11	fatigue	fatigue	NOUN
american_scientific_journal-766	287	12	,	,	PUNCT
american_scientific_journal-766	287	13	nausea	nausea	NOUN
american_scientific_journal-766	287	14	,	,	PUNCT
american_scientific_journal-766	287	15	dizziness	dizziness	NOUN
american_scientific_journal-766	287	16	,	,	PUNCT
american_scientific_journal-766	287	17	pruritis	pruritis	NOUN
american_scientific_journal-766	287	18	,	,	PUNCT
american_scientific_journal-766	287	19	upper	upper	ADJ
american_scientific_journal-766	287	20	respiratory	respiratory	ADJ
american_scientific_journal-766	287	21	tract	tract	NOUN
american_scientific_journal-766	287	22	infections	infection	NOUN
american_scientific_journal-766	287	23	,	,	PUNCT
american_scientific_journal-766	287	24	rash	rash	ADJ
american_scientific_journal-766	287	25	,	,	PUNCT
american_scientific_journal-766	287	26	back	back	NOUN
american_scientific_journal-766	287	27	pain	pain	NOUN
american_scientific_journal-766	287	28	,	,	PUNCT
american_scientific_journal-766	287	29	grade	grade	NOUN
american_scientific_journal-766	287	30	1	1	NUM
american_scientific_journal-766	287	31	anemia	anemia	NOUN
american_scientific_journal-766	287	32	,	,	PUNCT
american_scientific_journal-766	287	33	and	and	CCONJ
american_scientific_journal-766	287	34	grade	grade	NOUN
american_scientific_journal-766	287	35	4	4	NUM
american_scientific_journal-766	287	36	lymphopenia	lymphopenia	NOUN
american_scientific_journal-766	287	37	[	[	X
american_scientific_journal-766	287	38	70	70	NUM
american_scientific_journal-766	287	39	]	]	PUNCT
american_scientific_journal-766	287	40	.	.	PUNCT
american_scientific_journal-766	288	1	depression	depression	NOUN
american_scientific_journal-766	288	2	is	be	AUX
american_scientific_journal-766	288	3	a	a	DET
american_scientific_journal-766	288	4	common	common	ADJ
american_scientific_journal-766	288	5	side	side	NOUN
american_scientific_journal-766	288	6	effect	effect	NOUN
american_scientific_journal-766	288	7	of	of	ADP
american_scientific_journal-766	288	8	interferon	interferon	ADJ
american_scientific_journal-766	288	9	therapy	therapy	NOUN
american_scientific_journal-766	288	10	,	,	PUNCT
american_scientific_journal-766	288	11	and	and	CCONJ
american_scientific_journal-766	288	12	in	in	ADP
american_scientific_journal-766	288	13	the	the	DET
american_scientific_journal-766	288	14	fission	fission	NOUN
american_scientific_journal-766	288	15	study	study	NOUN
american_scientific_journal-766	288	16	,	,	PUNCT
american_scientific_journal-766	288	17	occurred	occur	VERB
american_scientific_journal-766	288	18	in	in	ADP
american_scientific_journal-766	288	19	14	14	NUM
american_scientific_journal-766	288	20	%	%	NOUN
american_scientific_journal-766	288	21	of	of	ADP
american_scientific_journal-766	288	22	patients	patient	NOUN
american_scientific_journal-766	288	23	receiving	receive	VERB
american_scientific_journal-766	288	24	peginterferon	peginterferon	NOUN
american_scientific_journal-766	288	25	,	,	PUNCT
american_scientific_journal-766	288	26	as	as	SCONJ
american_scientific_journal-766	288	27	compared	compare	VERB
american_scientific_journal-766	288	28	with	with	ADP
american_scientific_journal-766	288	29	5	5	NUM
american_scientific_journal-766	288	30	%	%	NOUN
american_scientific_journal-766	288	31	of	of	ADP
american_scientific_journal-766	288	32	patients	patient	NOUN
american_scientific_journal-766	288	33	receiving	receive	VERB
american_scientific_journal-766	288	34	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	288	35	plus	plus	CCONJ
american_scientific_journal-766	288	36	ribavirin	ribavirin	NOUN
american_scientific_journal-766	288	37	.	.	PUNCT
american_scientific_journal-766	289	1	in	in	ADP
american_scientific_journal-766	289	2	a	a	DET
american_scientific_journal-766	289	3	recent	recent	ADJ
american_scientific_journal-766	289	4	analysis	analysis	NOUN
american_scientific_journal-766	289	5	of	of	ADP
american_scientific_journal-766	289	6	the	the	DET
american_scientific_journal-766	289	7	impact	impact	NOUN
american_scientific_journal-766	289	8	of	of	ADP
american_scientific_journal-766	289	9	hcv	hcv	ADJ
american_scientific_journal-766	289	10	treatment	treatment	NOUN
american_scientific_journal-766	289	11	on	on	ADP
american_scientific_journal-766	289	12	quality	quality	NOUN
american_scientific_journal-766	289	13	of	of	ADP
american_scientific_journal-766	289	14	life	life	NOUN
american_scientific_journal-766	289	15	,	,	PUNCT
american_scientific_journal-766	289	16	in	in	ADP
american_scientific_journal-766	289	17	the	the	DET
american_scientific_journal-766	289	18	fission	fission	NOUN
american_scientific_journal-766	289	19	and	and	CCONJ
american_scientific_journal-766	289	20	positron	positron	NOUN
american_scientific_journal-766	289	21	trials	trial	NOUN
american_scientific_journal-766	289	22	,	,	PUNCT
american_scientific_journal-766	289	23	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	289	24	plus	plus	CCONJ
american_scientific_journal-766	289	25	ribavirin	ribavirin	NOUN
american_scientific_journal-766	289	26	was	be	AUX
american_scientific_journal-766	289	27	associated	associate	VERB
american_scientific_journal-766	289	28	with	with	ADP
american_scientific_journal-766	289	29	better	well	ADJ
american_scientific_journal-766	289	30	health	health	NOUN
american_scientific_journal-766	289	31	-	-	PUNCT
american_scientific_journal-766	289	32	related	relate	VERB
american_scientific_journal-766	289	33	quality	quality	NOUN
american_scientific_journal-766	289	34	of	of	ADP
american_scientific_journal-766	289	35	life	life	NOUN
american_scientific_journal-766	289	36	than	than	ADP
american_scientific_journal-766	289	37	peginterferon	peginterferon	NOUN
american_scientific_journal-766	289	38	plus	plus	CCONJ
american_scientific_journal-766	289	39	ribavirin	ribavirin	NOUN
american_scientific_journal-766	289	40	,	,	PUNCT
american_scientific_journal-766	289	41	and	and	CCONJ
american_scientific_journal-766	289	42	was	be	AUX
american_scientific_journal-766	289	43	15	15	NUM
american_scientific_journal-766	289	44	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3968818/%23bibr5-1756283x13515825	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3968818/%23bibr5-1756283x13515825	PROPN
american_scientific_journal-766	289	45	american	american	PROPN
american_scientific_journal-766	289	46	scientific	scientific	PROPN
american_scientific_journal-766	289	47	research	research	PROPN
american_scientific_journal-766	289	48	journal	journal	NOUN
american_scientific_journal-766	289	49	for	for	ADP
american_scientific_journal-766	289	50	engineering	engineering	NOUN
american_scientific_journal-766	289	51	,	,	PUNCT
american_scientific_journal-766	289	52	technology	technology	NOUN
american_scientific_journal-766	289	53	,	,	PUNCT
american_scientific_journal-766	289	54	and	and	CCONJ
american_scientific_journal-766	289	55	sciences	science	NOUN
american_scientific_journal-766	289	56	(	(	PUNCT
american_scientific_journal-766	289	57	asrjets	asrjet	NOUN
american_scientific_journal-766	289	58	)	)	PUNCT
american_scientific_journal-766	289	59	(	(	PUNCT
american_scientific_journal-766	289	60	2015	2015	NUM
american_scientific_journal-766	289	61	)	)	PUNCT
american_scientific_journal-766	289	62	volume	volume	NOUN
american_scientific_journal-766	289	63	13	13	NUM
american_scientific_journal-766	289	64	,	,	PUNCT
american_scientific_journal-766	289	65	no	no	DET
american_scientific_journal-766	289	66	1	1	NUM
american_scientific_journal-766	289	67	,	,	PUNCT
american_scientific_journal-766	289	68	pp	pp	ADV
american_scientific_journal-766	289	69	1	1	NUM
american_scientific_journal-766	289	70	-	-	SYM
american_scientific_journal-766	289	71	23	23	NUM
american_scientific_journal-766	289	72	similar	similar	ADJ
american_scientific_journal-766	289	73	to	to	ADP
american_scientific_journal-766	289	74	patients	patient	NOUN
american_scientific_journal-766	289	75	not	not	PART
american_scientific_journal-766	289	76	receiving	receive	VERB
american_scientific_journal-766	289	77	active	active	ADJ
american_scientific_journal-766	289	78	treatment	treatment	NOUN
american_scientific_journal-766	289	79	[	[	X
american_scientific_journal-766	289	80	85	85	NUM
american_scientific_journal-766	289	81	]	]	PUNCT
american_scientific_journal-766	289	82	.	.	PUNCT
american_scientific_journal-766	290	1	in	in	ADP
american_scientific_journal-766	290	2	the	the	DET
american_scientific_journal-766	290	3	monotherapy	monotherapy	NOUN
american_scientific_journal-766	290	4	treatment	treatment	NOUN
american_scientific_journal-766	290	5	groups	group	NOUN
american_scientific_journal-766	290	6	,	,	PUNCT
american_scientific_journal-766	290	7	nausea	nausea	NOUN
american_scientific_journal-766	290	8	and	and	CCONJ
american_scientific_journal-766	290	9	fatigue	fatigue	NOUN
american_scientific_journal-766	290	10	seemed	seem	VERB
american_scientific_journal-766	290	11	to	to	PART
american_scientific_journal-766	290	12	be	be	AUX
american_scientific_journal-766	290	13	the	the	DET
american_scientific_journal-766	290	14	only	only	ADJ
american_scientific_journal-766	290	15	adverse	adverse	ADJ
american_scientific_journal-766	290	16	events	event	NOUN
american_scientific_journal-766	290	17	possibly	possibly	ADV
american_scientific_journal-766	290	18	correlated	correlate	VERB
american_scientific_journal-766	290	19	to	to	ADP
american_scientific_journal-766	290	20	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	290	21	.	.	PUNCT
american_scientific_journal-766	291	1	an	an	DET
american_scientific_journal-766	291	2	overall	overall	ADJ
american_scientific_journal-766	291	3	improved	improved	ADJ
american_scientific_journal-766	291	4	tolerability	tolerability	NOUN
american_scientific_journal-766	291	5	was	be	AUX
american_scientific_journal-766	291	6	seen	see	VERB
american_scientific_journal-766	291	7	with	with	ADP
american_scientific_journal-766	291	8	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	291	9	compared	compare	VERB
american_scientific_journal-766	291	10	to	to	ADP
american_scientific_journal-766	291	11	the	the	DET
american_scientific_journal-766	291	12	interferon	interferon	NOUN
american_scientific_journal-766	291	13	-	-	PUNCT
american_scientific_journal-766	291	14	based	base	VERB
american_scientific_journal-766	291	15	regimens	regimen	NOUN
american_scientific_journal-766	291	16	.	.	PUNCT
american_scientific_journal-766	292	1	in	in	ADP
american_scientific_journal-766	292	2	march	march	PROPN
american_scientific_journal-766	292	3	2015	2015	NUM
american_scientific_journal-766	292	4	,	,	PUNCT
american_scientific_journal-766	292	5	gilead	gilead	PROPN
american_scientific_journal-766	292	6	sciences	sciences	PROPN
american_scientific_journal-766	292	7	said	say	VERB
american_scientific_journal-766	292	8	warnings	warning	NOUN
american_scientific_journal-766	292	9	to	to	ADP
american_scientific_journal-766	292	10	health	health	NOUN
american_scientific_journal-766	292	11	care	care	NOUN
american_scientific_journal-766	292	12	providers	provider	NOUN
american_scientific_journal-766	292	13	about	about	ADP
american_scientific_journal-766	292	14	nine	nine	NUM
american_scientific_journal-766	292	15	patients	patient	NOUN
american_scientific_journal-766	292	16	that	that	PRON
american_scientific_journal-766	292	17	began	begin	VERB
american_scientific_journal-766	292	18	taking	take	VERB
american_scientific_journal-766	292	19	its	its	PRON
american_scientific_journal-766	292	20	hepatitis	hepatitis	NOUN
american_scientific_journal-766	292	21	c	c	NOUN
american_scientific_journal-766	293	1	drugs	drug	NOUN
american_scientific_journal-766	293	2	harvoni	harvoni	X
american_scientific_journal-766	293	3	(	(	PUNCT
american_scientific_journal-766	293	4	ledipasvir	ledipasvir	PROPN
american_scientific_journal-766	293	5	/	/	SYM
american_scientific_journal-766	293	6	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	293	7	)	)	PUNCT
american_scientific_journal-766	293	8	or	or	CCONJ
american_scientific_journal-766	293	9	sovaldi(sofosbuvir	sovaldi(sofosbuvir	PROPN
american_scientific_journal-766	293	10	)	)	PUNCT
american_scientific_journal-766	293	11	along	along	ADP
american_scientific_journal-766	293	12	with	with	ADP
american_scientific_journal-766	293	13	the	the	DET
american_scientific_journal-766	293	14	heart	heart	NOUN
american_scientific_journal-766	293	15	treatments	treatment	VERB
american_scientific_journal-766	293	16	amiodarone	amiodarone	NOUN
american_scientific_journal-766	293	17	,	,	PUNCT
american_scientific_journal-766	293	18	bristol	bristol	NOUN
american_scientific_journal-766	293	19	-	-	PUNCT
american_scientific_journal-766	293	20	myers	myers	PROPN
american_scientific_journal-766	293	21	squibb	squibb	PROPN
american_scientific_journal-766	293	22	's	's	PART
american_scientific_journal-766	293	23	daklinza	daklinza	PROPN
american_scientific_journal-766	293	24	(	(	PUNCT
american_scientific_journal-766	293	25	daclatasvir	daclatasvir	PROPN
american_scientific_journal-766	293	26	)	)	PUNCT
american_scientific_journal-766	293	27	,	,	PUNCT
american_scientific_journal-766	293	28	or	or	CCONJ
american_scientific_journal-766	293	29	olysio	olysio	PROPN
american_scientific_journal-766	293	30	johnson	johnson	PROPN
american_scientific_journal-766	293	31	&	&	CCONJ
american_scientific_journal-766	293	32	johnson	johnson	PROPN
american_scientific_journal-766	293	33	's	's	PART
american_scientific_journal-766	293	34	(	(	PUNCT
american_scientific_journal-766	293	35	simeprevir	simeprevir	PROPN
american_scientific_journal-766	293	36	)	)	PUNCT
american_scientific_journal-766	293	37	developed	develop	VERB
american_scientific_journal-766	293	38	abnormally	abnormally	ADV
american_scientific_journal-766	293	39	slow	slow	ADJ
american_scientific_journal-766	293	40	heartbeats	heartbeat	NOUN
american_scientific_journal-766	293	41	and	and	CCONJ
american_scientific_journal-766	293	42	one	one	NUM
american_scientific_journal-766	293	43	died	die	VERB
american_scientific_journal-766	293	44	of	of	ADP
american_scientific_journal-766	293	45	cardiac	cardiac	ADJ
american_scientific_journal-766	293	46	arrest	arrest	NOUN
american_scientific_journal-766	293	47	.	.	PUNCT
american_scientific_journal-766	294	1	three	three	NUM
american_scientific_journal-766	294	2	required	require	VERB
american_scientific_journal-766	294	3	a	a	DET
american_scientific_journal-766	294	4	pacemaker	pacemaker	NOUN
american_scientific_journal-766	294	5	to	to	PART
american_scientific_journal-766	294	6	be	be	AUX
american_scientific_journal-766	294	7	inserted	insert	VERB
american_scientific_journal-766	294	8	.	.	PUNCT
american_scientific_journal-766	295	1	gilead	gilead	PROPN
american_scientific_journal-766	295	2	said	say	VERB
american_scientific_journal-766	295	3	the	the	DET
american_scientific_journal-766	295	4	combinations	combination	NOUN
american_scientific_journal-766	295	5	are	be	AUX
american_scientific_journal-766	295	6	n't	not	PART
american_scientific_journal-766	295	7	recommended	recommend	VERB
american_scientific_journal-766	295	8	and	and	CCONJ
american_scientific_journal-766	295	9	product	product	NOUN
american_scientific_journal-766	295	10	labels	label	NOUN
american_scientific_journal-766	295	11	will	will	AUX
american_scientific_journal-766	295	12	be	be	AUX
american_scientific_journal-766	295	13	updated	update	VERB
american_scientific_journal-766	295	14	[	[	X
american_scientific_journal-766	295	15	86	86	NUM
american_scientific_journal-766	295	16	]	]	PUNCT
american_scientific_journal-766	295	17	.	.	PUNCT
american_scientific_journal-766	296	1	2.2.5.6	2.2.5.6	NUM
american_scientific_journal-766	296	2	.	.	PUNCT
american_scientific_journal-766	296	3	drug	drug	NOUN
american_scientific_journal-766	296	4	interactions	interaction	NOUN
american_scientific_journal-766	296	5	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	296	6	is	be	AUX
american_scientific_journal-766	296	7	a	a	DET
american_scientific_journal-766	296	8	substrate	substrate	NOUN
american_scientific_journal-766	296	9	of	of	ADP
american_scientific_journal-766	296	10	p	p	NOUN
american_scientific_journal-766	296	11	-	-	PUNCT
american_scientific_journal-766	296	12	glycoprotein	glycoprotein	NOUN
american_scientific_journal-766	296	13	,	,	PUNCT
american_scientific_journal-766	296	14	a	a	DET
american_scientific_journal-766	296	15	transporter	transporter	NOUN
american_scientific_journal-766	296	16	protein	protein	NOUN
american_scientific_journal-766	296	17	that	that	PRON
american_scientific_journal-766	296	18	pumps	pump	VERB
american_scientific_journal-766	296	19	drugs	drug	NOUN
american_scientific_journal-766	296	20	and	and	CCONJ
american_scientific_journal-766	296	21	other	other	ADJ
american_scientific_journal-766	296	22	substances	substance	NOUN
american_scientific_journal-766	296	23	from	from	ADP
american_scientific_journal-766	296	24	intestinal	intestinal	ADJ
american_scientific_journal-766	296	25	epithelium	epithelium	NOUN
american_scientific_journal-766	296	26	cells	cell	NOUN
american_scientific_journal-766	296	27	back	back	ADV
american_scientific_journal-766	296	28	into	into	ADP
american_scientific_journal-766	296	29	the	the	DET
american_scientific_journal-766	296	30	gut	gut	NOUN
american_scientific_journal-766	296	31	.	.	PUNCT
american_scientific_journal-766	297	1	therefore	therefore	ADV
american_scientific_journal-766	297	2	,	,	PUNCT
american_scientific_journal-766	297	3	inducers	inducer	NOUN
american_scientific_journal-766	297	4	of	of	ADP
american_scientific_journal-766	297	5	intestinal	intestinal	ADJ
american_scientific_journal-766	297	6	p	p	NOUN
american_scientific_journal-766	297	7	-	-	PUNCT
american_scientific_journal-766	297	8	glycoprotein	glycoprotein	NOUN
american_scientific_journal-766	297	9	,	,	PUNCT
american_scientific_journal-766	297	10	such	such	ADJ
american_scientific_journal-766	297	11	as	as	ADP
american_scientific_journal-766	297	12	rifampicin	rifampicin	VERB
american_scientific_journal-766	297	13	could	could	AUX
american_scientific_journal-766	297	14	reduce	reduce	VERB
american_scientific_journal-766	297	15	the	the	DET
american_scientific_journal-766	297	16	absorption	absorption	NOUN
american_scientific_journal-766	297	17	of	of	ADP
american_scientific_journal-766	297	18	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	297	19	.	.	PUNCT
american_scientific_journal-766	298	1	in	in	ADP
american_scientific_journal-766	298	2	addition	addition	NOUN
american_scientific_journal-766	298	3	,	,	PUNCT
american_scientific_journal-766	298	4	coadministration	coadministration	NOUN
american_scientific_journal-766	298	5	of	of	ADP
american_scientific_journal-766	298	6	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	298	7	with	with	ADP
american_scientific_journal-766	298	8	anticonvulsants	anticonvulsant	NOUN
american_scientific_journal-766	298	9	,	,	PUNCT
american_scientific_journal-766	298	10	antimycobacterials	antimycobacterial	NOUN
american_scientific_journal-766	298	11	,	,	PUNCT
american_scientific_journal-766	298	12	and	and	CCONJ
american_scientific_journal-766	298	13	the	the	DET
american_scientific_journal-766	298	14	hiv	hiv	PROPN
american_scientific_journal-766	298	15	protease	protease	NOUN
american_scientific_journal-766	298	16	inhibitor	inhibitor	NOUN
american_scientific_journal-766	298	17	tipranavir	tipranavir	PROPN
american_scientific_journal-766	298	18	is	be	AUX
american_scientific_journal-766	298	19	expected	expect	VERB
american_scientific_journal-766	298	20	to	to	PART
american_scientific_journal-766	298	21	decrease	decrease	VERB
american_scientific_journal-766	298	22	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	298	23	concentration	concentration	NOUN
american_scientific_journal-766	298	24	.	.	PUNCT
american_scientific_journal-766	299	1	thus	thus	ADV
american_scientific_journal-766	299	2	,	,	PUNCT
american_scientific_journal-766	299	3	coadministration	coadministration	NOUN
american_scientific_journal-766	299	4	is	be	AUX
american_scientific_journal-766	299	5	not	not	PART
american_scientific_journal-766	299	6	recommended	recommend	VERB
american_scientific_journal-766	299	7	[	[	PUNCT
american_scientific_journal-766	299	8	87	87	NUM
american_scientific_journal-766	299	9	]	]	PUNCT
american_scientific_journal-766	299	10	.	.	PUNCT
american_scientific_journal-766	300	1	studies	study	NOUN
american_scientific_journal-766	300	2	have	have	AUX
american_scientific_journal-766	300	3	shown	show	VERB
american_scientific_journal-766	300	4	no	no	DET
american_scientific_journal-766	300	5	clinically	clinically	ADV
american_scientific_journal-766	300	6	significant	significant	ADJ
american_scientific_journal-766	300	7	interactions	interaction	NOUN
american_scientific_journal-766	300	8	between	between	ADP
american_scientific_journal-766	300	9	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	300	10	and	and	CCONJ
american_scientific_journal-766	300	11	the	the	DET
american_scientific_journal-766	300	12	following	follow	VERB
american_scientific_journal-766	300	13	drugs	drug	NOUN
american_scientific_journal-766	300	14	:	:	PUNCT
american_scientific_journal-766	300	15	cyclosporine	cyclosporine	NOUN
american_scientific_journal-766	300	16	,	,	PUNCT
american_scientific_journal-766	300	17	tacrolimus	tacrolimus	NOUN
american_scientific_journal-766	300	18	,	,	PUNCT
american_scientific_journal-766	300	19	methadone	methadone	NOUN
american_scientific_journal-766	300	20	,	,	PUNCT
american_scientific_journal-766	300	21	efavirenz	efavirenz	NOUN
american_scientific_journal-766	300	22	,	,	PUNCT
american_scientific_journal-766	300	23	rilpivirine	rilpivirine	NOUN
american_scientific_journal-766	300	24	,	,	PUNCT
american_scientific_journal-766	300	25	darunavir	darunavir	PROPN
american_scientific_journal-766	300	26	/	/	SYM
american_scientific_journal-766	300	27	ritonavir	ritonavir	PROPN
american_scientific_journal-766	300	28	,	,	PUNCT
american_scientific_journal-766	300	29	raltegravir	raltegravir	PROPN
american_scientific_journal-766	300	30	,	,	PUNCT
american_scientific_journal-766	300	31	and	and	CCONJ
american_scientific_journal-766	300	32	tenofovir	tenofovir	NOUN
american_scientific_journal-766	300	33	.	.	PUNCT
american_scientific_journal-766	301	1	no	no	DET
american_scientific_journal-766	301	2	dose	dose	NOUN
american_scientific_journal-766	301	3	adjustments	adjustment	NOUN
american_scientific_journal-766	301	4	are	be	AUX
american_scientific_journal-766	301	5	required	require	VERB
american_scientific_journal-766	301	6	in	in	ADP
american_scientific_journal-766	301	7	patients	patient	NOUN
american_scientific_journal-766	301	8	receiving	receive	VERB
american_scientific_journal-766	301	9	these	these	DET
american_scientific_journal-766	301	10	drugs	drug	NOUN
american_scientific_journal-766	301	11	along	along	ADP
american_scientific_journal-766	301	12	with	with	ADP
american_scientific_journal-766	301	13	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	302	1	[	[	X
american_scientific_journal-766	302	2	88	88	NUM
american_scientific_journal-766	302	3	]	]	PUNCT
american_scientific_journal-766	302	4	.	.	PUNCT
american_scientific_journal-766	303	1	3	3	X
american_scientific_journal-766	303	2	.	.	X
american_scientific_journal-766	303	3	conclusions	conclusion	NOUN
american_scientific_journal-766	303	4	and	and	CCONJ
american_scientific_journal-766	303	5	future	future	ADJ
american_scientific_journal-766	303	6	perspectives	perspective	NOUN
american_scientific_journal-766	303	7	from	from	ADP
american_scientific_journal-766	303	8	the	the	DET
american_scientific_journal-766	303	9	above	above	ADJ
american_scientific_journal-766	303	10	data	datum	NOUN
american_scientific_journal-766	303	11	,	,	PUNCT
american_scientific_journal-766	303	12	it	it	PRON
american_scientific_journal-766	303	13	seems	seem	VERB
american_scientific_journal-766	303	14	that	that	SCONJ
american_scientific_journal-766	303	15	clinical	clinical	ADJ
american_scientific_journal-766	303	16	research	research	NOUN
american_scientific_journal-766	303	17	in	in	ADP
american_scientific_journal-766	303	18	the	the	DET
american_scientific_journal-766	303	19	field	field	NOUN
american_scientific_journal-766	303	20	of	of	ADP
american_scientific_journal-766	303	21	new	new	ADJ
american_scientific_journal-766	303	22	treatments	treatment	NOUN
american_scientific_journal-766	303	23	for	for	ADP
american_scientific_journal-766	303	24	chronic	chronic	ADJ
american_scientific_journal-766	303	25	hepatitis	hepatitis	NOUN
american_scientific_journal-766	303	26	c	c	PROPN
american_scientific_journal-766	303	27	(	(	PUNCT
american_scientific_journal-766	303	28	hcv	hcv	PROPN
american_scientific_journal-766	303	29	)	)	PUNCT
american_scientific_journal-766	303	30	has	have	AUX
american_scientific_journal-766	303	31	been	be	AUX
american_scientific_journal-766	303	32	devoted	devote	VERB
american_scientific_journal-766	303	33	to	to	ADP
american_scientific_journal-766	303	34	developing	develop	VERB
american_scientific_journal-766	303	35	regimens	regimen	NOUN
american_scientific_journal-766	303	36	based	base	VERB
american_scientific_journal-766	303	37	on	on	ADP
american_scientific_journal-766	303	38	direct	direct	ADJ
american_scientific_journal-766	303	39	-	-	PUNCT
american_scientific_journal-766	303	40	acting	act	VERB
american_scientific_journal-766	303	41	antivirals	antiviral	NOUN
american_scientific_journal-766	303	42	(	(	PUNCT
american_scientific_journal-766	303	43	daas	daas	NOUN
american_scientific_journal-766	303	44	)	)	PUNCT
american_scientific_journal-766	303	45	,	,	PUNCT
american_scientific_journal-766	303	46	with	with	ADP
american_scientific_journal-766	303	47	the	the	DET
american_scientific_journal-766	303	48	goal	goal	NOUN
american_scientific_journal-766	303	49	of	of	ADP
american_scientific_journal-766	303	50	increasing	increase	VERB
american_scientific_journal-766	303	51	treatment	treatment	NOUN
american_scientific_journal-766	303	52	efficacy	efficacy	NOUN
american_scientific_journal-766	303	53	and	and	CCONJ
american_scientific_journal-766	303	54	improving	improve	VERB
american_scientific_journal-766	303	55	tolerability	tolerability	NOUN
american_scientific_journal-766	303	56	and	and	CCONJ
american_scientific_journal-766	303	57	safety	safety	NOUN
american_scientific_journal-766	303	58	.	.	PUNCT
american_scientific_journal-766	304	1	a	a	DET
american_scientific_journal-766	304	2	new	new	ADJ
american_scientific_journal-766	304	3	era	era	NOUN
american_scientific_journal-766	304	4	of	of	ADP
american_scientific_journal-766	304	5	successful	successful	ADJ
american_scientific_journal-766	304	6	interferon	interferon	ADJ
american_scientific_journal-766	304	7	-	-	PUNCT
american_scientific_journal-766	304	8	free	free	ADJ
american_scientific_journal-766	304	9	daa	daa	NOUN
american_scientific_journal-766	304	10	therapy	therapy	NOUN
american_scientific_journal-766	304	11	for	for	ADP
american_scientific_journal-766	304	12	hcv	hcv	PROPN
american_scientific_journal-766	304	13	is	be	AUX
american_scientific_journal-766	304	14	emerging	emerge	VERB
american_scientific_journal-766	304	15	,	,	PUNCT
american_scientific_journal-766	304	16	with	with	ADP
american_scientific_journal-766	304	17	potential	potential	NOUN
american_scientific_journal-766	304	18	to	to	PART
american_scientific_journal-766	304	19	broaden	broaden	VERB
american_scientific_journal-766	304	20	treatment	treatment	NOUN
american_scientific_journal-766	304	21	of	of	ADP
american_scientific_journal-766	304	22	hcv	hcv	NOUN
american_scientific_journal-766	304	23	to	to	PART
american_scientific_journal-766	304	24	include	include	VERB
american_scientific_journal-766	304	25	patient	patient	ADJ
american_scientific_journal-766	304	26	groups	group	NOUN
american_scientific_journal-766	304	27	who	who	PRON
american_scientific_journal-766	304	28	have	have	AUX
american_scientific_journal-766	304	29	either	either	CCONJ
american_scientific_journal-766	304	30	avoided	avoid	VERB
american_scientific_journal-766	304	31	or	or	CCONJ
american_scientific_journal-766	304	32	not	not	PART
american_scientific_journal-766	304	33	been	be	AUX
american_scientific_journal-766	304	34	suitable	suitable	ADJ
american_scientific_journal-766	304	35	for	for	ADP
american_scientific_journal-766	304	36	previous	previous	ADJ
american_scientific_journal-766	304	37	interferon	interferon	NOUN
american_scientific_journal-766	304	38	-	-	PUNCT
american_scientific_journal-766	304	39	based	base	VERB
american_scientific_journal-766	304	40	therapy	therapy	NOUN
american_scientific_journal-766	304	41	,	,	PUNCT
american_scientific_journal-766	304	42	and	and	CCONJ
american_scientific_journal-766	304	43	it	it	PRON
american_scientific_journal-766	304	44	is	be	AUX
american_scientific_journal-766	304	45	likely	likely	ADJ
american_scientific_journal-766	304	46	that	that	SCONJ
american_scientific_journal-766	304	47	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	304	48	will	will	AUX
american_scientific_journal-766	304	49	form	form	VERB
american_scientific_journal-766	304	50	the	the	DET
american_scientific_journal-766	304	51	backbone	backbone	NOUN
american_scientific_journal-766	304	52	of	of	ADP
american_scientific_journal-766	304	53	this	this	DET
american_scientific_journal-766	304	54	treatment	treatment	NOUN
american_scientific_journal-766	304	55	approach	approach	NOUN
american_scientific_journal-766	304	56	.	.	PUNCT
american_scientific_journal-766	305	1	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	305	2	considered	consider	VERB
american_scientific_journal-766	305	3	a	a	DET
american_scientific_journal-766	305	4	promising	promising	ADJ
american_scientific_journal-766	305	5	therapy	therapy	NOUN
american_scientific_journal-766	305	6	for	for	ADP
american_scientific_journal-766	305	7	chronic	chronic	ADJ
american_scientific_journal-766	305	8	hcv	hcv	NOUN
american_scientific_journal-766	305	9	infection	infection	NOUN
american_scientific_journal-766	305	10	,	,	PUNCT
american_scientific_journal-766	305	11	as	as	SCONJ
american_scientific_journal-766	305	12	it	it	PRON
american_scientific_journal-766	305	13	offers	offer	VERB
american_scientific_journal-766	305	14	several	several	ADJ
american_scientific_journal-766	305	15	advantages	advantage	NOUN
american_scientific_journal-766	305	16	over	over	ADP
american_scientific_journal-766	305	17	the	the	DET
american_scientific_journal-766	305	18	existing	exist	VERB
american_scientific_journal-766	305	19	therapies	therapy	NOUN
american_scientific_journal-766	305	20	,	,	PUNCT
american_scientific_journal-766	305	21	particularly	particularly	ADV
american_scientific_journal-766	305	22	in	in	ADP
american_scientific_journal-766	305	23	dealing	deal	VERB
american_scientific_journal-766	305	24	with	with	ADP
american_scientific_journal-766	305	25	patients	patient	NOUN
american_scientific_journal-766	305	26	with	with	ADP
american_scientific_journal-766	305	27	decompensated	decompensate	VERB
american_scientific_journal-766	305	28	liver	liver	NOUN
american_scientific_journal-766	305	29	disease	disease	NOUN
american_scientific_journal-766	305	30	and	and	CCONJ
american_scientific_journal-766	305	31	patients	patient	NOUN
american_scientific_journal-766	305	32	who	who	PRON
american_scientific_journal-766	305	33	can	can	AUX
american_scientific_journal-766	305	34	not	not	PART
american_scientific_journal-766	305	35	tolerate	tolerate	VERB
american_scientific_journal-766	305	36	interferon	interferon	ADJ
american_scientific_journal-766	305	37	-	-	PUNCT
american_scientific_journal-766	305	38	containing	contain	VERB
american_scientific_journal-766	305	39	therapies	therapy	NOUN
american_scientific_journal-766	305	40	.	.	PUNCT
american_scientific_journal-766	306	1	large	large	ADJ
american_scientific_journal-766	306	2	post	post	ADJ
american_scientific_journal-766	306	3	-	-	ADJ
american_scientific_journal-766	306	4	marketing	marketing	ADJ
american_scientific_journal-766	306	5	studies	study	NOUN
american_scientific_journal-766	306	6	,	,	PUNCT
american_scientific_journal-766	306	7	including	include	VERB
american_scientific_journal-766	306	8	pharmacovigilance	pharmacovigilance	NOUN
american_scientific_journal-766	306	9	and	and	CCONJ
american_scientific_journal-766	306	10	pharmacoepidemiological	pharmacoepidemiological	ADJ
american_scientific_journal-766	306	11	studies	study	NOUN
american_scientific_journal-766	306	12	,	,	PUNCT
american_scientific_journal-766	306	13	can	can	AUX
american_scientific_journal-766	306	14	solve	solve	VERB
american_scientific_journal-766	306	15	many	many	ADJ
american_scientific_journal-766	306	16	unanswered	unanswered	ADJ
american_scientific_journal-766	306	17	questions	question	NOUN
american_scientific_journal-766	306	18	for	for	ADP
american_scientific_journal-766	306	19	the	the	DET
american_scientific_journal-766	306	20	future	future	NOUN
american_scientific_journal-766	306	21	of	of	ADP
american_scientific_journal-766	306	22	this	this	DET
american_scientific_journal-766	306	23	novel	novel	ADJ
american_scientific_journal-766	306	24	drug	drug	NOUN
american_scientific_journal-766	306	25	.	.	PUNCT
american_scientific_journal-766	307	1	hepatitis	hepatitis	PROPN
american_scientific_journal-766	307	2	c	c	PROPN
american_scientific_journal-766	307	3	virus	virus	PROPN
american_scientific_journal-766	307	4	(	(	PUNCT
american_scientific_journal-766	307	5	hcv	hcv	PROPN
american_scientific_journal-766	307	6	)	)	PUNCT
american_scientific_journal-766	307	7	continues	continue	VERB
american_scientific_journal-766	307	8	to	to	PART
american_scientific_journal-766	307	9	be	be	AUX
american_scientific_journal-766	307	10	a	a	DET
american_scientific_journal-766	307	11	global	global	ADJ
american_scientific_journal-766	307	12	problem	problem	NOUN
american_scientific_journal-766	307	13	but	but	CCONJ
american_scientific_journal-766	307	14	with	with	ADP
american_scientific_journal-766	307	15	the	the	DET
american_scientific_journal-766	307	16	arrival	arrival	NOUN
american_scientific_journal-766	307	17	of	of	ADP
american_scientific_journal-766	307	18	new	new	ADJ
american_scientific_journal-766	307	19	drugs	drug	NOUN
american_scientific_journal-766	307	20	era	era	NOUN
american_scientific_journal-766	307	21	it	it	PRON
american_scientific_journal-766	307	22	is	be	AUX
american_scientific_journal-766	307	23	expected	expect	VERB
american_scientific_journal-766	307	24	to	to	PART
american_scientific_journal-766	307	25	move	move	VERB
american_scientific_journal-766	307	26	towards	towards	ADP
american_scientific_journal-766	307	27	exile	exile	NOUN
american_scientific_journal-766	307	28	and	and	CCONJ
american_scientific_journal-766	307	29	it	it	PRON
american_scientific_journal-766	307	30	is	be	AUX
american_scientific_journal-766	307	31	likely	likely	ADJ
american_scientific_journal-766	307	32	that	that	SCONJ
american_scientific_journal-766	307	33	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	307	34	will	will	AUX
american_scientific_journal-766	307	35	form	form	VERB
american_scientific_journal-766	307	36	the	the	DET
american_scientific_journal-766	307	37	cornerstone	cornerstone	NOUN
american_scientific_journal-766	307	38	of	of	ADP
american_scientific_journal-766	307	39	this	this	DET
american_scientific_journal-766	307	40	treatment	treatment	NOUN
american_scientific_journal-766	307	41	approach	approach	NOUN
american_scientific_journal-766	307	42	.	.	PUNCT
american_scientific_journal-766	308	1	on	on	ADP
american_scientific_journal-766	308	2	the	the	DET
american_scientific_journal-766	308	3	other	other	ADJ
american_scientific_journal-766	308	4	hand	hand	NOUN
american_scientific_journal-766	308	5	,	,	PUNCT
american_scientific_journal-766	308	6	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	308	7	commercialization	commercialization	NOUN
american_scientific_journal-766	308	8	will	will	AUX
american_scientific_journal-766	308	9	be	be	AUX
american_scientific_journal-766	308	10	the	the	DET
american_scientific_journal-766	308	11	key	key	ADJ
american_scientific_journal-766	308	12	moment	moment	NOUN
american_scientific_journal-766	308	13	to	to	PART
american_scientific_journal-766	308	14	address	address	VERB
american_scientific_journal-766	308	15	some	some	DET
american_scientific_journal-766	308	16	open	open	ADJ
american_scientific_journal-766	308	17	questions	question	NOUN
american_scientific_journal-766	308	18	with	with	ADP
american_scientific_journal-766	308	19	these	these	DET
american_scientific_journal-766	308	20	new	new	ADJ
american_scientific_journal-766	308	21	regimens	regimen	NOUN
american_scientific_journal-766	308	22	,	,	PUNCT
american_scientific_journal-766	308	23	as	as	SCONJ
american_scientific_journal-766	308	24	the	the	DET
american_scientific_journal-766	308	25	huge	huge	ADJ
american_scientific_journal-766	308	26	raise	raise	NOUN
american_scientific_journal-766	308	27	in	in	ADP
american_scientific_journal-766	308	28	treatment	treatment	NOUN
american_scientific_journal-766	308	29	costs	cost	NOUN
american_scientific_journal-766	308	30	will	will	AUX
american_scientific_journal-766	308	31	represent	represent	VERB
american_scientific_journal-766	308	32	the	the	DET
american_scientific_journal-766	308	33	first	first	ADJ
american_scientific_journal-766	308	34	problem	problem	NOUN
american_scientific_journal-766	308	35	to	to	PART
american_scientific_journal-766	308	36	solve	solve	VERB
american_scientific_journal-766	308	37	for	for	ADP
american_scientific_journal-766	308	38	national	national	ADJ
american_scientific_journal-766	308	39	health	health	PROPN
american_scientific_journal-766	308	40	care	care	NOUN
american_scientific_journal-766	308	41	services	service	NOUN
american_scientific_journal-766	308	42	.	.	PUNCT
american_scientific_journal-766	309	1	consequently	consequently	ADV
american_scientific_journal-766	309	2	,	,	PUNCT
american_scientific_journal-766	309	3	affordability	affordability	NOUN
american_scientific_journal-766	309	4	could	could	AUX
american_scientific_journal-766	309	5	be	be	AUX
american_scientific_journal-766	309	6	the	the	DET
american_scientific_journal-766	309	7	driving	drive	VERB
american_scientific_journal-766	309	8	force	force	NOUN
american_scientific_journal-766	309	9	for	for	ADP
american_scientific_journal-766	309	10	the	the	DET
american_scientific_journal-766	309	11	development	development	NOUN
american_scientific_journal-766	309	12	of	of	ADP
american_scientific_journal-766	309	13	new	new	ADJ
american_scientific_journal-766	309	14	strategies	strategy	NOUN
american_scientific_journal-766	309	15	in	in	ADP
american_scientific_journal-766	309	16	treatment	treatment	NOUN
american_scientific_journal-766	309	17	individualization	individualization	NOUN
american_scientific_journal-766	309	18	and	and	CCONJ
american_scientific_journal-766	309	19	the	the	DET
american_scientific_journal-766	309	20	approval	approval	NOUN
american_scientific_journal-766	309	21	of	of	ADP
american_scientific_journal-766	309	22	drugs	drug	NOUN
american_scientific_journal-766	309	23	from	from	ADP
american_scientific_journal-766	309	24	several	several	ADJ
american_scientific_journal-766	309	25	pharmaceutical	pharmaceutical	ADJ
american_scientific_journal-766	309	26	companies	company	NOUN
american_scientific_journal-766	309	27	and	and	CCONJ
american_scientific_journal-766	309	28	the	the	DET
american_scientific_journal-766	309	29	ensuing	ensue	VERB
american_scientific_journal-766	309	30	competition	competition	NOUN
american_scientific_journal-766	309	31	may	may	AUX
american_scientific_journal-766	309	32	result	result	VERB
american_scientific_journal-766	309	33	in	in	ADP
american_scientific_journal-766	309	34	lower	low	ADJ
american_scientific_journal-766	309	35	drug	drug	NOUN
american_scientific_journal-766	309	36	costs	cost	NOUN
american_scientific_journal-766	309	37	in	in	ADP
american_scientific_journal-766	309	38	the	the	DET
american_scientific_journal-766	309	39	future	future	NOUN
american_scientific_journal-766	309	40	.	.	PUNCT
american_scientific_journal-766	310	1	moreover	moreover	ADV
american_scientific_journal-766	310	2	,	,	PUNCT
american_scientific_journal-766	310	3	the	the	DET
american_scientific_journal-766	310	4	future	future	NOUN
american_scientific_journal-766	310	5	will	will	AUX
american_scientific_journal-766	310	6	evidence	evidence	VERB
american_scientific_journal-766	310	7	the	the	DET
american_scientific_journal-766	310	8	development	development	NOUN
american_scientific_journal-766	310	9	of	of	ADP
american_scientific_journal-766	310	10	much	much	ADV
american_scientific_journal-766	310	11	more	more	ADJ
american_scientific_journal-766	310	12	compounds	compound	NOUN
american_scientific_journal-766	310	13	that	that	PRON
american_scientific_journal-766	310	14	will	will	AUX
american_scientific_journal-766	310	15	provide	provide	VERB
american_scientific_journal-766	310	16	100	100	NUM
american_scientific_journal-766	310	17	%	%	NOUN
american_scientific_journal-766	310	18	efficacy	efficacy	NOUN
american_scientific_journal-766	310	19	within	within	ADP
american_scientific_journal-766	310	20	very	very	ADV
american_scientific_journal-766	310	21	16	16	NUM
american_scientific_journal-766	310	22	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3968818/%23bibr30-1756283x13515825	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3968818/%23bibr30-1756283x13515825	PROPN
american_scientific_journal-766	310	23	http://en.wikipedia.org/wiki/gilead_sciences	http://en.wikipedia.org/wiki/gilead_science	NOUN
american_scientific_journal-766	310	24	http://en.wikipedia.org/wiki/harvoni	http://en.wikipedia.org/wiki/harvoni	PROPN
american_scientific_journal-766	310	25	http://en.wikipedia.org/wiki/sovaldi	http://en.wikipedia.org/wiki/sovaldi	PROPN
american_scientific_journal-766	310	26	http://en.wikipedia.org/wiki/amiodarone	http://en.wikipedia.org/wiki/amiodarone	PROPN
american_scientific_journal-766	311	1	http://en.wikipedia.org/wiki/bristol-myers_squibb	http://en.wikipedia.org/wiki/bristol-myers_squibb	PROPN
american_scientific_journal-766	312	1	http://en.wikipedia.org/wiki/daclatasvir	http://en.wikipedia.org/wiki/daclatasvir	PROPN
american_scientific_journal-766	313	1	http://en.wikipedia.org/wiki/simeprevir	http://en.wikipedia.org/wiki/simeprevir	PROPN
american_scientific_journal-766	314	1	http://en.wikipedia.org/wiki/simeprevir	http://en.wikipedia.org/wiki/simeprevir	PROPN
american_scientific_journal-766	314	2	http://en.wikipedia.org/wiki/simeprevir	http://en.wikipedia.org/wiki/simeprevir	PROPN
american_scientific_journal-766	314	3	http://en.wikipedia.org/wiki/cardiac_arrest	http://en.wikipedia.org/wiki/cardiac_arr	ADJ
american_scientific_journal-766	314	4	http://en.wikipedia.org/wiki/pacemaker	http://en.wikipedia.org/wiki/pacemaker	PROPN
american_scientific_journal-766	314	5	http://en.wikipedia.org/wiki/p-glycoprotein	http://en.wikipedia.org/wiki/p-glycoprotein	PROPN
american_scientific_journal-766	315	1	http://en.wikipedia.org/wiki/intestinal_epithelium	http://en.wikipedia.org/wiki/intestinal_epithelium	NOUN
american_scientific_journal-766	316	1	http://en.wikipedia.org/wiki/tipranavir	http://en.wikipedia.org/wiki/tipranavir	PROPN
american_scientific_journal-766	316	2	american	american	PROPN
american_scientific_journal-766	316	3	scientific	scientific	PROPN
american_scientific_journal-766	316	4	research	research	PROPN
american_scientific_journal-766	316	5	journal	journal	NOUN
american_scientific_journal-766	316	6	for	for	ADP
american_scientific_journal-766	316	7	engineering	engineering	NOUN
american_scientific_journal-766	316	8	,	,	PUNCT
american_scientific_journal-766	316	9	technology	technology	NOUN
american_scientific_journal-766	316	10	,	,	PUNCT
american_scientific_journal-766	316	11	and	and	CCONJ
american_scientific_journal-766	316	12	sciences	science	NOUN
american_scientific_journal-766	316	13	(	(	PUNCT
american_scientific_journal-766	316	14	asrjets	asrjet	NOUN
american_scientific_journal-766	316	15	)	)	PUNCT
american_scientific_journal-766	316	16	(	(	PUNCT
american_scientific_journal-766	316	17	2015	2015	NUM
american_scientific_journal-766	316	18	)	)	PUNCT
american_scientific_journal-766	316	19	volume	volume	NOUN
american_scientific_journal-766	316	20	13	13	NUM
american_scientific_journal-766	316	21	,	,	PUNCT
american_scientific_journal-766	316	22	no	no	DET
american_scientific_journal-766	316	23	1	1	NUM
american_scientific_journal-766	316	24	,	,	PUNCT
american_scientific_journal-766	316	25	pp	pp	ADV
american_scientific_journal-766	316	26	1	1	NUM
american_scientific_journal-766	316	27	-	-	SYM
american_scientific_journal-766	316	28	23	23	NUM
american_scientific_journal-766	316	29	short	short	ADJ
american_scientific_journal-766	316	30	periods	period	NOUN
american_scientific_journal-766	316	31	of	of	ADP
american_scientific_journal-766	316	32	therapy	therapy	NOUN
american_scientific_journal-766	316	33	,	,	PUNCT
american_scientific_journal-766	316	34	simplification	simplification	NOUN
american_scientific_journal-766	316	35	of	of	ADP
american_scientific_journal-766	316	36	treatment	treatment	NOUN
american_scientific_journal-766	316	37	management	management	NOUN
american_scientific_journal-766	316	38	,	,	PUNCT
american_scientific_journal-766	316	39	lower	low	ADJ
american_scientific_journal-766	316	40	costs	cost	NOUN
american_scientific_journal-766	316	41	and	and	CCONJ
american_scientific_journal-766	316	42	the	the	DET
american_scientific_journal-766	316	43	dream	dream	NOUN
american_scientific_journal-766	316	44	of	of	ADP
american_scientific_journal-766	316	45	hcv	hcv	NOUN
american_scientific_journal-766	316	46	eradication	eradication	NOUN
american_scientific_journal-766	316	47	seems	seem	VERB
american_scientific_journal-766	316	48	to	to	PART
american_scientific_journal-766	316	49	be	be	AUX
american_scientific_journal-766	316	50	possible	possible	ADJ
american_scientific_journal-766	316	51	in	in	ADP
american_scientific_journal-766	316	52	the	the	DET
american_scientific_journal-766	316	53	near	near	ADJ
american_scientific_journal-766	316	54	future	future	NOUN
american_scientific_journal-766	316	55	.	.	PUNCT
american_scientific_journal-766	317	1	acknowledgment	acknowledgment	NOUN
american_scientific_journal-766	317	2	we	we	PRON
american_scientific_journal-766	317	3	are	be	AUX
american_scientific_journal-766	317	4	grateful	grateful	ADJ
american_scientific_journal-766	317	5	to	to	ADP
american_scientific_journal-766	317	6	the	the	DET
american_scientific_journal-766	317	7	stuff	stuff	NOUN
american_scientific_journal-766	317	8	members	member	NOUN
american_scientific_journal-766	317	9	of	of	ADP
american_scientific_journal-766	317	10	zoology	zoology	NOUN
american_scientific_journal-766	317	11	departments	department	NOUN
american_scientific_journal-766	317	12	,	,	PUNCT
american_scientific_journal-766	317	13	faculty	faculty	NOUN
american_scientific_journal-766	317	14	of	of	ADP
american_scientific_journal-766	317	15	science	science	NOUN
american_scientific_journal-766	317	16	,	,	PUNCT
american_scientific_journal-766	317	17	beni	beni	ADJ
american_scientific_journal-766	317	18	suef	suef	PROPN
american_scientific_journal-766	317	19	university	university	NOUN
american_scientific_journal-766	317	20	,	,	PUNCT
american_scientific_journal-766	317	21	for	for	ADP
american_scientific_journal-766	317	22	providing	provide	VERB
american_scientific_journal-766	317	23	facilities	facility	NOUN
american_scientific_journal-766	317	24	to	to	PART
american_scientific_journal-766	317	25	finish	finish	VERB
american_scientific_journal-766	317	26	this	this	DET
american_scientific_journal-766	317	27	work	work	NOUN
american_scientific_journal-766	317	28	.	.	PUNCT
american_scientific_journal-766	318	1	compliance	compliance	NOUN
american_scientific_journal-766	318	2	with	with	ADP
american_scientific_journal-766	318	3	ethics	ethic	NOUN
american_scientific_journal-766	318	4	requirements	requirement	NOUN
american_scientific_journal-766	318	5	this	this	DET
american_scientific_journal-766	318	6	article	article	NOUN
american_scientific_journal-766	318	7	does	do	AUX
american_scientific_journal-766	318	8	not	not	PART
american_scientific_journal-766	318	9	contain	contain	VERB
american_scientific_journal-766	318	10	any	any	DET
american_scientific_journal-766	318	11	studies	study	NOUN
american_scientific_journal-766	318	12	with	with	ADP
american_scientific_journal-766	318	13	human	human	ADJ
american_scientific_journal-766	318	14	or	or	CCONJ
american_scientific_journal-766	318	15	animal	animal	NOUN
american_scientific_journal-766	318	16	subjects	subject	NOUN
american_scientific_journal-766	318	17	.	.	PUNCT
american_scientific_journal-766	319	1	source	source	NOUN
american_scientific_journal-766	319	2	of	of	ADP
american_scientific_journal-766	319	3	support	support	NOUN
american_scientific_journal-766	319	4	nil	nil	NOUN
american_scientific_journal-766	319	5	conflict	conflict	NOUN
american_scientific_journal-766	319	6	of	of	ADP
american_scientific_journal-766	319	7	interest	interest	NOUN
american_scientific_journal-766	319	8	the	the	DET
american_scientific_journal-766	319	9	authors	author	NOUN
american_scientific_journal-766	319	10	have	have	AUX
american_scientific_journal-766	319	11	declared	declare	VERB
american_scientific_journal-766	319	12	no	no	DET
american_scientific_journal-766	319	13	conflict	conflict	NOUN
american_scientific_journal-766	319	14	of	of	ADP
american_scientific_journal-766	319	15	interest	interest	NOUN
american_scientific_journal-766	319	16	.	.	PUNCT
american_scientific_journal-766	320	1	references	reference	NOUN
american_scientific_journal-766	320	2	[	[	X
american_scientific_journal-766	320	3	1	1	X
american_scientific_journal-766	320	4	]	]	X
american_scientific_journal-766	320	5	mohd	mohd	PROPN
american_scientific_journal-766	320	6	hk	hk	PROPN
american_scientific_journal-766	320	7	,	,	PUNCT
american_scientific_journal-766	320	8	groeger	groeger	PROPN
american_scientific_journal-766	320	9	j	j	PROPN
american_scientific_journal-766	320	10	,	,	PUNCT
american_scientific_journal-766	320	11	flaxman	flaxman	NOUN
american_scientific_journal-766	320	12	ad	ad	NOUN
american_scientific_journal-766	320	13	,	,	PUNCT
american_scientific_journal-766	320	14	wiersma	wiersma	PROPN
american_scientific_journal-766	320	15	st,(2013	st,(2013	PROPN
american_scientific_journal-766	320	16	)	)	PUNCT
american_scientific_journal-766	320	17	,	,	PUNCT
american_scientific_journal-766	320	18	global	global	ADJ
american_scientific_journal-766	320	19	epidemiology	epidemiology	NOUN
american_scientific_journal-766	320	20	of	of	ADP
american_scientific_journal-766	320	21	hepatitis	hepatitis	PROPN
american_scientific_journal-766	320	22	c	c	PROPN
american_scientific_journal-766	320	23	virus	virus	NOUN
american_scientific_journal-766	320	24	infection	infection	NOUN
american_scientific_journal-766	320	25	:	:	PUNCT
american_scientific_journal-766	320	26	new	new	ADJ
american_scientific_journal-766	320	27	estimates	estimate	NOUN
american_scientific_journal-766	320	28	of	of	ADP
american_scientific_journal-766	320	29	age	age	NOUN
american_scientific_journal-766	320	30	-	-	PUNCT
american_scientific_journal-766	320	31	specific	specific	ADJ
american_scientific_journal-766	320	32	antibody	antibody	NOUN
american_scientific_journal-766	320	33	to	to	ADP
american_scientific_journal-766	320	34	hcv	hcv	VERB
american_scientific_journal-766	320	35	seroprevalence	seroprevalence	NOUN
american_scientific_journal-766	320	36	,	,	PUNCT
american_scientific_journal-766	320	37	hepatology	hepatology	NOUN
american_scientific_journal-766	320	38	,	,	PUNCT
american_scientific_journal-766	320	39	57,1333–42	57,1333–42	PROPN
american_scientific_journal-766	320	40	.	.	PUNCT
american_scientific_journal-766	321	1	[	[	X
american_scientific_journal-766	321	2	2	2	NUM
american_scientific_journal-766	321	3	]	]	PUNCT
american_scientific_journal-766	321	4	naggie	naggie	NOUN
american_scientific_journal-766	321	5	s	s	PROPN
american_scientific_journal-766	321	6	,	,	PUNCT
american_scientific_journal-766	321	7	patel	patel	PROPN
american_scientific_journal-766	321	8	k	k	PROPN
american_scientific_journal-766	321	9	,	,	PUNCT
american_scientific_journal-766	321	10	mchutchison	mchutchison	PROPN
american_scientific_journal-766	321	11	j	j	PROPN
american_scientific_journal-766	321	12	,	,	PUNCT
american_scientific_journal-766	321	13	(	(	PUNCT
american_scientific_journal-766	321	14	2010),hepatitis	2010),hepatitis	NUM
american_scientific_journal-766	321	15	c	c	PROPN
american_scientific_journal-766	321	16	virus	virus	NOUN
american_scientific_journal-766	321	17	directly	directly	ADV
american_scientific_journal-766	321	18	acting	act	VERB
american_scientific_journal-766	321	19	antivirals	antiviral	NOUN
american_scientific_journal-766	321	20	:	:	PUNCT
american_scientific_journal-766	321	21	current	current	ADJ
american_scientific_journal-766	321	22	developments	development	NOUN
american_scientific_journal-766	321	23	with	with	ADP
american_scientific_journal-766	321	24	ns3/4a	ns3/4a	NOUN
american_scientific_journal-766	321	25	hcv	hcv	NOUN
american_scientific_journal-766	321	26	serine	serine	NOUN
american_scientific_journal-766	321	27	protease	protease	NOUN
american_scientific_journal-766	321	28	inhibitors	inhibitor	NOUN
american_scientific_journal-766	321	29	,	,	PUNCT
american_scientific_journal-766	321	30	j	j	PROPN
american_scientific_journal-766	321	31	antimicrob	antimicrob	PROPN
american_scientific_journal-766	321	32	chemother	chemother	PROPN
american_scientific_journal-766	321	33	.	.	PUNCT
american_scientific_journal-766	322	1	65	65	NUM
american_scientific_journal-766	322	2	,	,	PUNCT
american_scientific_journal-766	322	3	2063–69	2063–69	NUM
american_scientific_journal-766	322	4	.	.	PUNCT
american_scientific_journal-766	323	1	[	[	X
american_scientific_journal-766	323	2	3	3	NUM
american_scientific_journal-766	323	3	]	]	PUNCT
american_scientific_journal-766	323	4	perz	perz	PROPN
american_scientific_journal-766	323	5	jf	jf	PROPN
american_scientific_journal-766	323	6	,	,	PUNCT
american_scientific_journal-766	323	7	armstrong	armstrong	PROPN
american_scientific_journal-766	323	8	gl	gl	PROPN
american_scientific_journal-766	323	9	,	,	PUNCT
american_scientific_journal-766	323	10	farrington	farrington	PROPN
american_scientific_journal-766	323	11	la	la	PROPN
american_scientific_journal-766	323	12	,	,	PUNCT
american_scientific_journal-766	323	13	hutin	hutin	PROPN
american_scientific_journal-766	323	14	yj	yj	PROPN
american_scientific_journal-766	323	15	,	,	PUNCT
american_scientific_journal-766	323	16	bell	bell	NOUN
american_scientific_journal-766	323	17	bp,(2006	bp,(2006	NOUN
american_scientific_journal-766	323	18	)	)	PUNCT
american_scientific_journal-766	323	19	,	,	PUNCT
american_scientific_journal-766	323	20	the	the	DET
american_scientific_journal-766	323	21	contributions	contribution	NOUN
american_scientific_journal-766	323	22	of	of	ADP
american_scientific_journal-766	323	23	hepatitis	hepatitis	PROPN
american_scientific_journal-766	323	24	b	b	PROPN
american_scientific_journal-766	323	25	virus	virus	NOUN
american_scientific_journal-766	323	26	and	and	CCONJ
american_scientific_journal-766	323	27	hepatitis	hepatitis	PROPN
american_scientific_journal-766	323	28	c	c	PROPN
american_scientific_journal-766	323	29	virus	virus	NOUN
american_scientific_journal-766	323	30	infections	infection	NOUN
american_scientific_journal-766	323	31	to	to	ADP
american_scientific_journal-766	323	32	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	323	33	and	and	CCONJ
american_scientific_journal-766	323	34	primary	primary	ADJ
american_scientific_journal-766	323	35	liver	liver	NOUN
american_scientific_journal-766	323	36	cancer	cancer	NOUN
american_scientific_journal-766	323	37	worldwide	worldwide	ADV
american_scientific_journal-766	323	38	,	,	PUNCT
american_scientific_journal-766	323	39	hepatology	hepatology	NOUN
american_scientific_journal-766	323	40	,	,	PUNCT
american_scientific_journal-766	323	41	45	45	NUM
american_scientific_journal-766	323	42	(	(	PUNCT
american_scientific_journal-766	323	43	4	4	NUM
american_scientific_journal-766	323	44	)	)	PUNCT
american_scientific_journal-766	323	45	,	,	PUNCT
american_scientific_journal-766	323	46	529–38	529–38	NUM
american_scientific_journal-766	323	47	.	.	PUNCT
american_scientific_journal-766	324	1	[	[	X
american_scientific_journal-766	324	2	4	4	X
american_scientific_journal-766	324	3	]	]	PUNCT
american_scientific_journal-766	324	4	kayali	kayali	VERB
american_scientific_journal-766	324	5	z	z	NOUN
american_scientific_journal-766	324	6	,	,	PUNCT
american_scientific_journal-766	324	7	labrecque	labrecque	PROPN
american_scientific_journal-766	324	8	dr	dr	PROPN
american_scientific_journal-766	324	9	,	,	PUNCT
american_scientific_journal-766	324	10	schmidt	schmidt	PROPN
american_scientific_journal-766	324	11	wn	wn	PROPN
american_scientific_journal-766	324	12	,	,	PUNCT
american_scientific_journal-766	324	13	(	(	PUNCT
american_scientific_journal-766	324	14	2006),treatment	2006),treatment	NUM
american_scientific_journal-766	324	15	of	of	ADP
american_scientific_journal-766	324	16	hepatitis	hepatitis	PROPN
american_scientific_journal-766	324	17	c	c	PROPN
american_scientific_journal-766	324	18	cryoglobulinemia	cryoglobulinemia	NOUN
american_scientific_journal-766	324	19	:	:	PUNCT
american_scientific_journal-766	324	20	mission	mission	NOUN
american_scientific_journal-766	324	21	and	and	CCONJ
american_scientific_journal-766	324	22	challenges	challenge	NOUN
american_scientific_journal-766	324	23	,	,	PUNCT
american_scientific_journal-766	324	24	curr	curr	PROPN
american_scientific_journal-766	324	25	treat	treat	NOUN
american_scientific_journal-766	324	26	options	option	NOUN
american_scientific_journal-766	324	27	gastroenterol	gastroenterol	NOUN
american_scientific_journal-766	324	28	,	,	PUNCT
american_scientific_journal-766	324	29	9,497–507	9,497–507	NUM
american_scientific_journal-766	324	30	.	.	PUNCT
american_scientific_journal-766	325	1	[	[	X
american_scientific_journal-766	325	2	5	5	X
american_scientific_journal-766	325	3	]	]	X
american_scientific_journal-766	325	4	messina	messina	PROPN
american_scientific_journal-766	325	5	jp	jp	PROPN
american_scientific_journal-766	325	6	,	,	PUNCT
american_scientific_journal-766	325	7	humphreys	humphreys	PROPN
american_scientific_journal-766	325	8	i	i	PROPN
american_scientific_journal-766	325	9	,	,	PUNCT
american_scientific_journal-766	325	10	flaxman	flaxman	PROPN
american_scientific_journal-766	325	11	a	a	NOUN
american_scientific_journal-766	325	12	,	,	PUNCT
american_scientific_journal-766	325	13	brown	brown	ADJ
american_scientific_journal-766	325	14	a	a	PRON
american_scientific_journal-766	325	15	,	,	PUNCT
american_scientific_journal-766	325	16	cooke	cooke	PROPN
american_scientific_journal-766	325	17	gs	gs	PROPN
american_scientific_journal-766	325	18	,	,	PUNCT
american_scientific_journal-766	325	19	et	et	PROPN
american_scientific_journal-766	325	20	al	al	PROPN
american_scientific_journal-766	325	21	.	.	PROPN
american_scientific_journal-766	325	22	,(2015	,(2015	PROPN
american_scientific_journal-766	325	23	)	)	PUNCT
american_scientific_journal-766	325	24	,	,	PUNCT
american_scientific_journal-766	325	25	global	global	ADJ
american_scientific_journal-766	325	26	distribution	distribution	NOUN
american_scientific_journal-766	325	27	and	and	CCONJ
american_scientific_journal-766	325	28	prevalence	prevalence	NOUN
american_scientific_journal-766	325	29	of	of	ADP
american_scientific_journal-766	325	30	hepatitis	hepatitis	PROPN
american_scientific_journal-766	325	31	c	c	PROPN
american_scientific_journal-766	325	32	virus	virus	NOUN
american_scientific_journal-766	325	33	genotypes	genotype	NOUN
american_scientific_journal-766	325	34	,	,	PUNCT
american_scientific_journal-766	325	35	hepatology	hepatology	NOUN
american_scientific_journal-766	325	36	,	,	PUNCT
american_scientific_journal-766	325	37	61	61	NUM
american_scientific_journal-766	325	38	,	,	PUNCT
american_scientific_journal-766	325	39	77	77	NUM
american_scientific_journal-766	325	40	-	-	SYM
american_scientific_journal-766	325	41	87	87	NUM
american_scientific_journal-766	325	42	.	.	PUNCT
american_scientific_journal-766	326	1	[	[	X
american_scientific_journal-766	326	2	6	6	NUM
american_scientific_journal-766	326	3	]	]	X
american_scientific_journal-766	326	4	armstrong	armstrong	PROPN
american_scientific_journal-766	326	5	gl	gl	PROPN
american_scientific_journal-766	326	6	,	,	PUNCT
american_scientific_journal-766	326	7	wasley	wasley	PROPN
american_scientific_journal-766	326	8	a	a	NOUN
american_scientific_journal-766	326	9	,	,	PUNCT
american_scientific_journal-766	326	10	simard	simard	PROPN
american_scientific_journal-766	326	11	ep	ep	PROPN
american_scientific_journal-766	326	12	,	,	PUNCT
american_scientific_journal-766	326	13	mcquillan	mcquillan	PROPN
american_scientific_journal-766	326	14	gm	gm	PROPN
american_scientific_journal-766	326	15	,	,	PUNCT
american_scientific_journal-766	326	16	kuhnert	kuhnert	PROPN
american_scientific_journal-766	326	17	wl	wl	PROPN
american_scientific_journal-766	326	18	,	,	PUNCT
american_scientific_journal-766	326	19	alter	alter	PROPN
american_scientific_journal-766	326	20	mj	mj	PROPN
american_scientific_journal-766	326	21	,	,	PUNCT
american_scientific_journal-766	326	22	(	(	PUNCT
american_scientific_journal-766	326	23	2002),the	2002),the	PRON
american_scientific_journal-766	326	24	prevalence	prevalence	NOUN
american_scientific_journal-766	326	25	of	of	ADP
american_scientific_journal-766	326	26	hepatitis	hepatitis	PROPN
american_scientific_journal-766	326	27	c	c	PROPN
american_scientific_journal-766	326	28	virus	virus	NOUN
american_scientific_journal-766	326	29	infection	infection	NOUN
american_scientific_journal-766	326	30	in	in	ADP
american_scientific_journal-766	326	31	the	the	DET
american_scientific_journal-766	326	32	united	united	PROPN
american_scientific_journal-766	326	33	states	states	PROPN
american_scientific_journal-766	326	34	,	,	PUNCT
american_scientific_journal-766	326	35	1999	1999	NUM
american_scientific_journal-766	326	36	through	through	ADP
american_scientific_journal-766	326	37	2002	2002	NUM
american_scientific_journal-766	326	38	,	,	PUNCT
american_scientific_journal-766	326	39	ann	ann	PROPN
american_scientific_journal-766	326	40	intern	intern	NOUN
american_scientific_journal-766	326	41	med	me	VERB
american_scientific_journal-766	326	42	,	,	PUNCT
american_scientific_journal-766	326	43	144,705	144,705	NUM
american_scientific_journal-766	326	44	-	-	SYM
american_scientific_journal-766	326	45	14	14	NUM
american_scientific_journal-766	326	46	.	.	PUNCT
american_scientific_journal-766	327	1	[	[	X
american_scientific_journal-766	327	2	7	7	X
american_scientific_journal-766	327	3	]	]	PUNCT
american_scientific_journal-766	327	4	razavi	razavi	NOUN
american_scientific_journal-766	327	5	h	h	PROPN
american_scientific_journal-766	327	6	,	,	PUNCT
american_scientific_journal-766	327	7	el	el	PROPN
american_scientific_journal-766	327	8	-	-	PUNCT
american_scientific_journal-766	327	9	khoury	khoury	PROPN
american_scientific_journal-766	327	10	ac	ac	PROPN
american_scientific_journal-766	327	11	,	,	PUNCT
american_scientific_journal-766	327	12	elbasha	elbasha	PROPN
american_scientific_journal-766	327	13	e	e	PROPN
american_scientific_journal-766	327	14	,	,	PUNCT
american_scientific_journal-766	327	15	estes	este	NOUN
american_scientific_journal-766	327	16	c	c	PROPN
american_scientific_journal-766	327	17	,	,	PUNCT
american_scientific_journal-766	327	18	pasini	pasini	PROPN
american_scientific_journal-766	327	19	k	k	PROPN
american_scientific_journal-766	327	20	,	,	PUNCT
american_scientific_journal-766	327	21	poynard	poynard	PROPN
american_scientific_journal-766	327	22	t	t	PROPN
american_scientific_journal-766	327	23	,	,	PUNCT
american_scientific_journal-766	327	24	kumar	kumar	PROPN
american_scientific_journal-766	327	25	r	r	PROPN
american_scientific_journal-766	327	26	,	,	PUNCT
american_scientific_journal-766	327	27	(	(	PUNCT
american_scientific_journal-766	327	28	2013),chronic	2013),chronic	NUM
american_scientific_journal-766	327	29	hepatitis	hepatitis	NOUN
american_scientific_journal-766	327	30	c	c	PROPN
american_scientific_journal-766	327	31	virus	virus	NOUN
american_scientific_journal-766	327	32	(	(	PUNCT
american_scientific_journal-766	327	33	hcv	hcv	NOUN
american_scientific_journal-766	327	34	)	)	PUNCT
american_scientific_journal-766	327	35	disease	disease	NOUN
american_scientific_journal-766	327	36	burden	burden	NOUN
american_scientific_journal-766	327	37	and	and	CCONJ
american_scientific_journal-766	327	38	cost	cost	NOUN
american_scientific_journal-766	327	39	in	in	ADP
american_scientific_journal-766	327	40	the	the	DET
american_scientific_journal-766	327	41	united	united	PROPN
american_scientific_journal-766	327	42	states	states	PROPN
american_scientific_journal-766	327	43	,	,	PUNCT
american_scientific_journal-766	327	44	hepatology	hepatology	NOUN
american_scientific_journal-766	327	45	,	,	PUNCT
american_scientific_journal-766	327	46	57(6	57(6	NUM
american_scientific_journal-766	327	47	)	)	PUNCT
american_scientific_journal-766	327	48	,	,	PUNCT
american_scientific_journal-766	327	49	2164–70	2164–70	NUM
american_scientific_journal-766	328	1	[	[	X
american_scientific_journal-766	328	2	8	8	NUM
american_scientific_journal-766	328	3	]	]	X
american_scientific_journal-766	328	4	hatzakis	hatzaki	NOUN
american_scientific_journal-766	328	5	a	a	PRON
american_scientific_journal-766	328	6	,	,	PUNCT
american_scientific_journal-766	328	7	wait	wait	VERB
american_scientific_journal-766	328	8	s	s	NOUN
american_scientific_journal-766	328	9	,	,	PUNCT
american_scientific_journal-766	328	10	bruix	bruix	VERB
american_scientific_journal-766	328	11	j	j	PROPN
american_scientific_journal-766	328	12	,	,	PUNCT
american_scientific_journal-766	328	13	buti	buti	PROPN
american_scientific_journal-766	328	14	m	m	PROPN
american_scientific_journal-766	328	15	,	,	PUNCT
american_scientific_journal-766	328	16	carballo	carballo	PROPN
american_scientific_journal-766	328	17	,	,	PUNCT
american_scientific_journal-766	328	18	m	m	PROPN
american_scientific_journal-766	328	19	,	,	PUNCT
american_scientific_journal-766	328	20	et	et	PROPN
american_scientific_journal-766	328	21	al	al	PROPN
american_scientific_journal-766	328	22	,	,	PUNCT
american_scientific_journal-766	328	23	(	(	PUNCT
american_scientific_journal-766	328	24	2011),the	2011),the	DET
american_scientific_journal-766	328	25	state	state	NOUN
american_scientific_journal-766	328	26	of	of	ADP
american_scientific_journal-766	328	27	hepatitis	hepatitis	PROPN
american_scientific_journal-766	328	28	b	b	PROPN
american_scientific_journal-766	328	29	and	and	CCONJ
american_scientific_journal-766	328	30	c	c	PROPN
american_scientific_journal-766	328	31	in	in	ADP
american_scientific_journal-766	328	32	europe	europe	PROPN
american_scientific_journal-766	328	33	:	:	PUNCT
american_scientific_journal-766	328	34	report	report	VERB
american_scientific_journal-766	328	35	from	from	ADP
american_scientific_journal-766	328	36	the	the	DET
american_scientific_journal-766	328	37	hepatitis	hepatitis	PROPN
american_scientific_journal-766	328	38	b	b	PROPN
american_scientific_journal-766	328	39	and	and	CCONJ
american_scientific_journal-766	328	40	c	c	PROPN
american_scientific_journal-766	328	41	summit	summit	NOUN
american_scientific_journal-766	328	42	conference	conference	NOUN
american_scientific_journal-766	328	43	,	,	PUNCT
american_scientific_journal-766	328	44	j	j	PROPN
american_scientific_journal-766	328	45	viral	viral	ADJ
american_scientific_journal-766	328	46	hepatol	hepatol	ADJ
american_scientific_journal-766	328	47	,	,	PUNCT
american_scientific_journal-766	328	48	18(1	18(1	NUM
american_scientific_journal-766	328	49	)	)	PUNCT
american_scientific_journal-766	328	50	,	,	PUNCT
american_scientific_journal-766	328	51	1	1	NUM
american_scientific_journal-766	328	52	-	-	SYM
american_scientific_journal-766	328	53	16	16	NUM
american_scientific_journal-766	328	54	.	.	PUNCT
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american_scientific_journal-766	329	2	9	9	NUM
american_scientific_journal-766	329	3	]	]	SYM
american_scientific_journal-766	329	4	papatheodoridis	papatheodoridi	NOUN
american_scientific_journal-766	329	5	,	,	PUNCT
american_scientific_journal-766	329	6	g	g	NOUN
american_scientific_journal-766	329	7	,	,	PUNCT
american_scientific_journal-766	329	8	hatzakis	hatzaki	NOUN
american_scientific_journal-766	329	9	,	,	PUNCT
american_scientific_journal-766	329	10	a	a	DET
american_scientific_journal-766	329	11	,	,	PUNCT
american_scientific_journal-766	329	12	(	(	PUNCT
american_scientific_journal-766	329	13	2012	2012	NUM
american_scientific_journal-766	329	14	)	)	PUNCT
american_scientific_journal-766	329	15	,	,	PUNCT
american_scientific_journal-766	329	16	public	public	ADJ
american_scientific_journal-766	329	17	health	health	NOUN
american_scientific_journal-766	329	18	issues	issue	NOUN
american_scientific_journal-766	329	19	of	of	ADP
american_scientific_journal-766	329	20	hepatitis	hepatitis	PROPN
american_scientific_journal-766	329	21	c	c	PROPN
american_scientific_journal-766	329	22	virus	virus	NOUN
american_scientific_journal-766	329	23	infection	infection	NOUN
american_scientific_journal-766	329	24	,	,	PUNCT
american_scientific_journal-766	329	25	best	good	ADJ
american_scientific_journal-766	329	26	practice	practice	NOUN
american_scientific_journal-766	329	27	&	&	CCONJ
american_scientific_journal-766	329	28	research	research	NOUN
american_scientific_journal-766	329	29	clinical	clinical	ADJ
american_scientific_journal-766	329	30	gastroenterololgy	gastroenterololgy	NOUN
american_scientific_journal-766	329	31	,	,	PUNCT
american_scientific_journal-766	329	32	26,371	26,371	NUM
american_scientific_journal-766	329	33	-	-	SYM
american_scientific_journal-766	329	34	80	80	NUM
american_scientific_journal-766	329	35	.	.	PUNCT
american_scientific_journal-766	330	1	17	17	NUM
american_scientific_journal-766	330	2	http://www.ncbi.nlm.nih.gov/pubmed/?term=razavi%20h%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=razavi%20h%5bauth%5d	NOUN
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american_scientific_journal-766	330	4	http://www.ncbi.nlm.nih.gov/pubmed/?term=elbasha%20e%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=elbasha%20e%5bauth%5d	PROPN
american_scientific_journal-766	330	5	http://www.ncbi.nlm.nih.gov/pubmed/?term=estes%20c%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=estes%20c%5bauth%5d	PROPN
american_scientific_journal-766	330	6	http://www.ncbi.nlm.nih.gov/pubmed/?term=pasini%20k%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=pasini%20k%5bauth%5d	PROPN
american_scientific_journal-766	330	7	http://www.ncbi.nlm.nih.gov/pubmed/?term=poynard%20t%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=poynard%20t%5bauth%5d	VERB
american_scientific_journal-766	330	8	http://www.ncbi.nlm.nih.gov/pubmed/?term=kumar%20r%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=kumar%20r%5bauth%5d	ADJ
american_scientific_journal-766	330	9	american	american	PROPN
american_scientific_journal-766	330	10	scientific	scientific	ADJ
american_scientific_journal-766	330	11	research	research	PROPN
american_scientific_journal-766	330	12	journal	journal	NOUN
american_scientific_journal-766	330	13	for	for	ADP
american_scientific_journal-766	330	14	engineering	engineering	NOUN
american_scientific_journal-766	330	15	,	,	PUNCT
american_scientific_journal-766	330	16	technology	technology	NOUN
american_scientific_journal-766	330	17	,	,	PUNCT
american_scientific_journal-766	330	18	and	and	CCONJ
american_scientific_journal-766	330	19	sciences	science	NOUN
american_scientific_journal-766	330	20	(	(	PUNCT
american_scientific_journal-766	330	21	asrjets	asrjet	NOUN
american_scientific_journal-766	330	22	)	)	PUNCT
american_scientific_journal-766	330	23	(	(	PUNCT
american_scientific_journal-766	330	24	2015	2015	NUM
american_scientific_journal-766	330	25	)	)	PUNCT
american_scientific_journal-766	330	26	volume	volume	NOUN
american_scientific_journal-766	330	27	13	13	NUM
american_scientific_journal-766	330	28	,	,	PUNCT
american_scientific_journal-766	330	29	no	no	DET
american_scientific_journal-766	330	30	1	1	NUM
american_scientific_journal-766	330	31	,	,	PUNCT
american_scientific_journal-766	330	32	pp	pp	ADV
american_scientific_journal-766	330	33	1	1	NUM
american_scientific_journal-766	330	34	-	-	SYM
american_scientific_journal-766	330	35	23	23	NUM
american_scientific_journal-766	331	1	[	[	SYM
american_scientific_journal-766	331	2	10	10	NUM
american_scientific_journal-766	331	3	]	]	X
american_scientific_journal-766	331	4	european	european	PROPN
american_scientific_journal-766	331	5	association	association	PROPN
american_scientific_journal-766	331	6	for	for	ADP
american_scientific_journal-766	331	7	the	the	DET
american_scientific_journal-766	331	8	study	study	NOUN
american_scientific_journal-766	331	9	of	of	ADP
american_scientific_journal-766	331	10	the	the	DET
american_scientific_journal-766	331	11	liver	liver	NOUN
american_scientific_journal-766	331	12	(	(	PUNCT
american_scientific_journal-766	331	13	easl),(2011	easl),(2011	X
american_scientific_journal-766	331	14	)	)	PUNCT
american_scientific_journal-766	331	15	,	,	PUNCT
american_scientific_journal-766	331	16	clinical	clinical	ADJ
american_scientific_journal-766	331	17	practice	practice	NOUN
american_scientific_journal-766	331	18	guidelines	guideline	NOUN
american_scientific_journal-766	331	19	:	:	PUNCT
american_scientific_journal-766	331	20	management	management	NOUN
american_scientific_journal-766	331	21	of	of	ADP
american_scientific_journal-766	331	22	hepatitis	hepatitis	PROPN
american_scientific_journal-766	331	23	c	c	PROPN
american_scientific_journal-766	331	24	virus	virus	NOUN
american_scientific_journal-766	331	25	infection	infection	NOUN
american_scientific_journal-766	331	26	,	,	PUNCT
american_scientific_journal-766	331	27	j	j	PROPN
american_scientific_journal-766	331	28	hepatol	hepatol	ADJ
american_scientific_journal-766	331	29	,	,	PUNCT
american_scientific_journal-766	331	30	55,245–64	55,245–64	PROPN
american_scientific_journal-766	331	31	.	.	PUNCT
american_scientific_journal-766	332	1	[	[	X
american_scientific_journal-766	332	2	11	11	NUM
american_scientific_journal-766	332	3	]	]	X
american_scientific_journal-766	332	4	nguyen	nguyen	NOUN
american_scientific_journal-766	332	5	lh	lh	PROPN
american_scientific_journal-766	332	6	,	,	PUNCT
american_scientific_journal-766	332	7	ko	ko	PROPN
american_scientific_journal-766	332	8	s	s	PROPN
american_scientific_journal-766	332	9	,	,	PUNCT
american_scientific_journal-766	332	10	wong	wong	PROPN
american_scientific_journal-766	332	11	ss	ss	PROPN
american_scientific_journal-766	332	12	,	,	PUNCT
american_scientific_journal-766	332	13	tran	tran	PROPN
american_scientific_journal-766	332	14	ps	ps	PROPN
american_scientific_journal-766	332	15	,	,	PUNCT
american_scientific_journal-766	332	16	trinh	trinh	PROPN
american_scientific_journal-766	332	17	hn	hn	PROPN
american_scientific_journal-766	332	18	,	,	PUNCT
american_scientific_journal-766	332	19	et	et	PROPN
american_scientific_journal-766	332	20	al	al	PROPN
american_scientific_journal-766	332	21	.	.	PROPN
american_scientific_journal-766	332	22	,(2011	,(2011	PUNCT
american_scientific_journal-766	332	23	)	)	PUNCT
american_scientific_journal-766	332	24	,	,	PUNCT
american_scientific_journal-766	332	25	ethnic	ethnic	ADJ
american_scientific_journal-766	332	26	differences	difference	NOUN
american_scientific_journal-766	332	27	in	in	ADP
american_scientific_journal-766	332	28	viral	viral	ADJ
american_scientific_journal-766	332	29	dominance	dominance	NOUN
american_scientific_journal-766	332	30	patterns	pattern	NOUN
american_scientific_journal-766	332	31	in	in	ADP
american_scientific_journal-766	332	32	patients	patient	NOUN
american_scientific_journal-766	332	33	with	with	ADP
american_scientific_journal-766	332	34	hepatitis	hepatitis	PROPN
american_scientific_journal-766	332	35	b	b	PROPN
american_scientific_journal-766	332	36	virus	virus	NOUN
american_scientific_journal-766	332	37	and	and	CCONJ
american_scientific_journal-766	332	38	c	c	NOUN
american_scientific_journal-766	332	39	virus	virus	NOUN
american_scientific_journal-766	332	40	dual	dual	ADJ
american_scientific_journal-766	332	41	infection	infection	NOUN
american_scientific_journal-766	332	42	,	,	PUNCT
american_scientific_journal-766	332	43	hepatology	hepatology	NOUN
american_scientific_journal-766	332	44	,	,	PUNCT
american_scientific_journal-766	332	45	53,1839	53,1839	NUM
american_scientific_journal-766	332	46	-	-	SYM
american_scientific_journal-766	332	47	45	45	NUM
american_scientific_journal-766	332	48	.	.	PUNCT
american_scientific_journal-766	333	1	[	[	X
american_scientific_journal-766	333	2	12	12	NUM
american_scientific_journal-766	333	3	]	]	PUNCT
american_scientific_journal-766	333	4	lindenbach	lindenbach	PROPN
american_scientific_journal-766	333	5	,	,	PUNCT
american_scientific_journal-766	333	6	bd	bd	PROPN
american_scientific_journal-766	333	7	,	,	PUNCT
american_scientific_journal-766	333	8	rice	rice	NOUN
american_scientific_journal-766	333	9	,	,	PUNCT
american_scientific_journal-766	333	10	cm	cm	PROPN
american_scientific_journal-766	333	11	,	,	PUNCT
american_scientific_journal-766	333	12	(	(	PUNCT
american_scientific_journal-766	333	13	2005	2005	NUM
american_scientific_journal-766	333	14	)	)	PUNCT
american_scientific_journal-766	333	15	,	,	PUNCT
american_scientific_journal-766	333	16	unraveling	unravel	VERB
american_scientific_journal-766	333	17	hepatitis	hepatitis	PROPN
american_scientific_journal-766	333	18	c	c	PROPN
american_scientific_journal-766	333	19	virus	virus	NOUN
american_scientific_journal-766	333	20	replication	replication	NOUN
american_scientific_journal-766	333	21	from	from	ADP
american_scientific_journal-766	333	22	genome	genome	NOUN
american_scientific_journal-766	333	23	to	to	ADP
american_scientific_journal-766	333	24	function	function	NOUN
american_scientific_journal-766	333	25	,	,	PUNCT
american_scientific_journal-766	333	26	nature	nature	NOUN
american_scientific_journal-766	333	27	,	,	PUNCT
american_scientific_journal-766	333	28	436,933–38	436,933–38	PROPN
american_scientific_journal-766	333	29	.	.	PUNCT
american_scientific_journal-766	334	1	[	[	X
american_scientific_journal-766	334	2	13	13	NUM
american_scientific_journal-766	334	3	]	]	PUNCT
american_scientific_journal-766	334	4	shimotohno	shimotohno	NOUN
american_scientific_journal-766	334	5	k1	k1	PROPN
american_scientific_journal-766	334	6	,	,	PUNCT
american_scientific_journal-766	334	7	tanji	tanji	NOUN
american_scientific_journal-766	334	8	y	y	NOUN
american_scientific_journal-766	334	9	,	,	PUNCT
american_scientific_journal-766	334	10	hirowatari	hirowatari	PROPN
american_scientific_journal-766	334	11	y	y	PROPN
american_scientific_journal-766	334	12	,	,	PUNCT
american_scientific_journal-766	334	13	komoda	komoda	PROPN
american_scientific_journal-766	334	14	y	y	PROPN
american_scientific_journal-766	334	15	,	,	PUNCT
american_scientific_journal-766	334	16	kato	kato	PROPN
american_scientific_journal-766	334	17	n	n	CCONJ
american_scientific_journal-766	334	18	,	,	PUNCT
american_scientific_journal-766	334	19	hijikata	hijikata	PROPN
american_scientific_journal-766	334	20	m,(1995	m,(1995	PROPN
american_scientific_journal-766	334	21	)	)	PUNCT
american_scientific_journal-766	334	22	,	,	PUNCT
american_scientific_journal-766	334	23	processing	processing	NOUN
american_scientific_journal-766	334	24	of	of	ADP
american_scientific_journal-766	334	25	the	the	DET
american_scientific_journal-766	334	26	hepatitis	hepatitis	PROPN
american_scientific_journal-766	334	27	c	c	PROPN
american_scientific_journal-766	334	28	virus	virus	NOUN
american_scientific_journal-766	334	29	precursor	precursor	NOUN
american_scientific_journal-766	334	30	protein	protein	NOUN
american_scientific_journal-766	334	31	,	,	PUNCT
american_scientific_journal-766	334	32	j	j	PROPN
american_scientific_journal-766	334	33	hepatol	hepatol	ADJ
american_scientific_journal-766	334	34	,	,	PUNCT
american_scientific_journal-766	334	35	22(1	22(1	NUM
american_scientific_journal-766	334	36	suppl),87	suppl),87	NOUN
american_scientific_journal-766	334	37	-	-	PUNCT
american_scientific_journal-766	334	38	92	92	NUM
american_scientific_journal-766	334	39	.	.	PUNCT
american_scientific_journal-766	335	1	[	[	X
american_scientific_journal-766	335	2	14	14	NUM
american_scientific_journal-766	335	3	]	]	PUNCT
american_scientific_journal-766	335	4	branch	branch	NOUN
american_scientific_journal-766	335	5	ad	ad	NOUN
american_scientific_journal-766	335	6	,	,	PUNCT
american_scientific_journal-766	335	7	stumpp	stumpp	PROPN
american_scientific_journal-766	335	8	dd	dd	PROPN
american_scientific_journal-766	335	9	,	,	PUNCT
american_scientific_journal-766	335	10	gutiezrre	gutiezrre	ADJ
american_scientific_journal-766	335	11	ja,(2005	ja,(2005	NOUN
american_scientific_journal-766	335	12	)	)	PUNCT
american_scientific_journal-766	335	13	,	,	PUNCT
american_scientific_journal-766	335	14	the	the	DET
american_scientific_journal-766	335	15	hepatitis	hepatitis	PROPN
american_scientific_journal-766	335	16	virus	virus	NOUN
american_scientific_journal-766	335	17	alternate	alternate	ADJ
american_scientific_journal-766	335	18	reading	reading	NOUN
american_scientific_journal-766	335	19	frame	frame	NOUN
american_scientific_journal-766	335	20	(	(	PUNCT
american_scientific_journal-766	335	21	arf	arf	NOUN
american_scientific_journal-766	335	22	)	)	PUNCT
american_scientific_journal-766	335	23	and	and	CCONJ
american_scientific_journal-766	335	24	its	its	PRON
american_scientific_journal-766	335	25	family	family	NOUN
american_scientific_journal-766	335	26	of	of	ADP
american_scientific_journal-766	335	27	navel	navel	NOUN
american_scientific_journal-766	335	28	products	product	NOUN
american_scientific_journal-766	335	29	:	:	PUNCT
american_scientific_journal-766	335	30	the	the	DET
american_scientific_journal-766	335	31	alternate	alternate	ADJ
american_scientific_journal-766	335	32	reading	reading	NOUN
american_scientific_journal-766	335	33	frame	frame	NOUN
american_scientific_journal-766	335	34	protein/	protein/	NUM
american_scientific_journal-766	335	35	f	f	NOUN
american_scientific_journal-766	335	36	-	-	PUNCT
american_scientific_journal-766	335	37	protein	protein	NOUN
american_scientific_journal-766	335	38	,	,	PUNCT
american_scientific_journal-766	335	39	the	the	DET
american_scientific_journal-766	335	40	doubleframe	doubleframe	NOUN
american_scientific_journal-766	335	41	shift	shift	NOUN
american_scientific_journal-766	335	42	protein	protein	NOUN
american_scientific_journal-766	335	43	,	,	PUNCT
american_scientific_journal-766	335	44	and	and	CCONJ
american_scientific_journal-766	335	45	others	other	NOUN
american_scientific_journal-766	335	46	,	,	PUNCT
american_scientific_journal-766	335	47	semin	semin	PROPN
american_scientific_journal-766	335	48	liv	liv	PROPN
american_scientific_journal-766	335	49	dis	dis	PROPN
american_scientific_journal-766	335	50	,	,	PUNCT
american_scientific_journal-766	335	51	25,105	25,105	NUM
american_scientific_journal-766	335	52	-	-	SYM
american_scientific_journal-766	335	53	17	17	NUM
american_scientific_journal-766	335	54	.	.	PUNCT
american_scientific_journal-766	336	1	[	[	X
american_scientific_journal-766	336	2	15	15	NUM
american_scientific_journal-766	336	3	]	]	X
american_scientific_journal-766	336	4	varaklioti	varaklioti	NOUN
american_scientific_journal-766	336	5	a	a	DET
american_scientific_journal-766	336	6	,	,	PUNCT
american_scientific_journal-766	336	7	vassilaki	vassilaki	PROPN
american_scientific_journal-766	336	8	,	,	PUNCT
american_scientific_journal-766	336	9	n	n	PROPN
american_scientific_journal-766	336	10	,	,	PUNCT
american_scientific_journal-766	336	11	georgopoulou	georgopoulou	PROPN
american_scientific_journal-766	336	12	,	,	PUNCT
american_scientific_journal-766	336	13	u	u	PROPN
american_scientific_journal-766	336	14	,	,	PUNCT
american_scientific_journal-766	336	15	(	(	PUNCT
american_scientific_journal-766	336	16	2002	2002	NUM
american_scientific_journal-766	336	17	)	)	PUNCT
american_scientific_journal-766	336	18	,	,	PUNCT
american_scientific_journal-766	336	19	alternate	alternate	ADJ
american_scientific_journal-766	336	20	translation	translation	NOUN
american_scientific_journal-766	336	21	occurs	occur	VERB
american_scientific_journal-766	336	22	within	within	ADP
american_scientific_journal-766	336	23	the	the	DET
american_scientific_journal-766	336	24	core	core	NOUN
american_scientific_journal-766	336	25	coding	code	VERB
american_scientific_journal-766	336	26	region	region	NOUN
american_scientific_journal-766	336	27	of	of	ADP
american_scientific_journal-766	336	28	the	the	DET
american_scientific_journal-766	336	29	hepatitis	hepatitis	NOUN
american_scientific_journal-766	336	30	c	c	PROPN
american_scientific_journal-766	336	31	viral	viral	ADJ
american_scientific_journal-766	336	32	genome	genome	NOUN
american_scientific_journal-766	336	33	,	,	PUNCT
american_scientific_journal-766	336	34	j	j	PROPN
american_scientific_journal-766	336	35	biol	biol	PROPN
american_scientific_journal-766	336	36	chem	chem	NOUN
american_scientific_journal-766	336	37	,	,	PUNCT
american_scientific_journal-766	336	38	277(20	277(20	NUM
american_scientific_journal-766	336	39	)	)	PUNCT
american_scientific_journal-766	336	40	,	,	PUNCT
american_scientific_journal-766	336	41	17713	17713	NUM
american_scientific_journal-766	336	42	-	-	SYM
american_scientific_journal-766	336	43	21	21	NUM
american_scientific_journal-766	336	44	.	.	PUNCT
american_scientific_journal-766	337	1	[	[	X
american_scientific_journal-766	337	2	16	16	NUM
american_scientific_journal-766	337	3	]	]	PUNCT
american_scientific_journal-766	337	4	appel	appel	X
american_scientific_journal-766	337	5	n	n	CCONJ
american_scientific_journal-766	337	6	,	,	PUNCT
american_scientific_journal-766	337	7	schaller	schaller	PROPN
american_scientific_journal-766	337	8	t	t	PROPN
american_scientific_journal-766	337	9	,	,	PUNCT
american_scientific_journal-766	337	10	penin	penin	ADJ
american_scientific_journal-766	337	11	f	f	NOUN
american_scientific_journal-766	337	12	,	,	PUNCT
american_scientific_journal-766	337	13	bartenschlager	bartenschlager	NOUN
american_scientific_journal-766	337	14	r,(2006	r,(2006	PROPN
american_scientific_journal-766	337	15	)	)	PUNCT
american_scientific_journal-766	337	16	,	,	PUNCT
american_scientific_journal-766	337	17	from	from	ADP
american_scientific_journal-766	337	18	structure	structure	NOUN
american_scientific_journal-766	337	19	to	to	PART
american_scientific_journal-766	337	20	function	function	VERB
american_scientific_journal-766	337	21	:	:	PUNCT
american_scientific_journal-766	337	22	new	new	ADJ
american_scientific_journal-766	337	23	insights	insight	NOUN
american_scientific_journal-766	337	24	into	into	ADP
american_scientific_journal-766	337	25	hepatitis	hepatitis	PROPN
american_scientific_journal-766	337	26	c	c	PROPN
american_scientific_journal-766	337	27	virus	virus	NOUN
american_scientific_journal-766	337	28	rna	rna	NOUN
american_scientific_journal-766	337	29	replication	replication	NOUN
american_scientific_journal-766	337	30	,	,	PUNCT
american_scientific_journal-766	337	31	j	j	PROPN
american_scientific_journal-766	337	32	biol	biol	PROPN
american_scientific_journal-766	337	33	chem	chem	NOUN
american_scientific_journal-766	337	34	,	,	PUNCT
american_scientific_journal-766	337	35	281,9833–36	281,9833–36	NUM
american_scientific_journal-766	337	36	.	.	PUNCT
american_scientific_journal-766	338	1	[	[	X
american_scientific_journal-766	338	2	17	17	NUM
american_scientific_journal-766	338	3	]	]	X
american_scientific_journal-766	338	4	ma	ma	PROPN
american_scientific_journal-766	338	5	y	y	PROPN
american_scientific_journal-766	338	6	,	,	PUNCT
american_scientific_journal-766	338	7	yates	yates	PROPN
american_scientific_journal-766	338	8	j	j	PROPN
american_scientific_journal-766	338	9	,	,	PUNCT
american_scientific_journal-766	338	10	liang	liang	PROPN
american_scientific_journal-766	338	11	y	y	PROPN
american_scientific_journal-766	338	12	,	,	PUNCT
american_scientific_journal-766	338	13	lemon	lemon	PROPN
american_scientific_journal-766	338	14	sm	sm	PROPN
american_scientific_journal-766	338	15	,	,	PUNCT
american_scientific_journal-766	338	16	yi	yi	PROPN
american_scientific_journal-766	338	17	m,(2008	m,(2008	PROPN
american_scientific_journal-766	338	18	)	)	PUNCT
american_scientific_journal-766	338	19	,	,	PUNCT
american_scientific_journal-766	338	20	ns3	ns3	NOUN
american_scientific_journal-766	338	21	helicase	helicase	NOUN
american_scientific_journal-766	338	22	domains	domain	NOUN
american_scientific_journal-766	338	23	involved	involve	VERB
american_scientific_journal-766	338	24	in	in	ADP
american_scientific_journal-766	338	25	infectious	infectious	ADJ
american_scientific_journal-766	338	26	intracellular	intracellular	ADJ
american_scientific_journal-766	338	27	hepatitis	hepatitis	NOUN
american_scientific_journal-766	338	28	c	c	PROPN
american_scientific_journal-766	338	29	virus	virus	NOUN
american_scientific_journal-766	338	30	particle	particle	NOUN
american_scientific_journal-766	338	31	assembly	assembly	NOUN
american_scientific_journal-766	338	32	,	,	PUNCT
american_scientific_journal-766	338	33	j	j	PROPN
american_scientific_journal-766	338	34	virol	virol	NOUN
american_scientific_journal-766	338	35	,	,	PUNCT
american_scientific_journal-766	338	36	82,7624–39	82,7624–39	ADV
american_scientific_journal-766	338	37	.	.	PUNCT
american_scientific_journal-766	339	1	[	[	X
american_scientific_journal-766	339	2	18	18	NUM
american_scientific_journal-766	339	3	]	]	SYM
american_scientific_journal-766	339	4	alexopoulou	alexopoulou	NOUN
american_scientific_journal-766	339	5	,	,	PUNCT
american_scientific_journal-766	339	6	a	a	DET
american_scientific_journal-766	339	7	,	,	PUNCT
american_scientific_journal-766	339	8	karayiannis	karayiannis	PROPN
american_scientific_journal-766	339	9	,	,	PUNCT
american_scientific_journal-766	339	10	p	p	X
american_scientific_journal-766	339	11	,	,	PUNCT
american_scientific_journal-766	339	12	(	(	PUNCT
american_scientific_journal-766	339	13	2015	2015	NUM
american_scientific_journal-766	339	14	)	)	PUNCT
american_scientific_journal-766	339	15	,	,	PUNCT
american_scientific_journal-766	339	16	interferon	interferon	NOUN
american_scientific_journal-766	339	17	-	-	PUNCT
american_scientific_journal-766	339	18	based	base	VERB
american_scientific_journal-766	339	19	combination	combination	NOUN
american_scientific_journal-766	339	20	treatment	treatment	NOUN
american_scientific_journal-766	339	21	for	for	ADP
american_scientific_journal-766	339	22	chronic	chronic	ADJ
american_scientific_journal-766	339	23	hepatitis	hepatitis	NOUN
american_scientific_journal-766	339	24	c	c	PROPN
american_scientific_journal-766	339	25	in	in	ADP
american_scientific_journal-766	339	26	the	the	DET
american_scientific_journal-766	339	27	era	era	NOUN
american_scientific_journal-766	339	28	of	of	ADP
american_scientific_journal-766	339	29	direct	direct	ADJ
american_scientific_journal-766	339	30	acting	act	VERB
american_scientific_journal-766	339	31	antivirals	antiviral	NOUN
american_scientific_journal-766	339	32	,	,	PUNCT
american_scientific_journal-766	339	33	ann	ann	PROPN
american_scientific_journal-766	339	34	gastroenterol	gastroenterol	PROPN
american_scientific_journal-766	339	35	,	,	PUNCT
american_scientific_journal-766	339	36	28(1	28(1	NOUN
american_scientific_journal-766	339	37	)	)	PUNCT
american_scientific_journal-766	339	38	,	,	PUNCT
american_scientific_journal-766	339	39	55–65	55–65	NUM
american_scientific_journal-766	339	40	.	.	PUNCT
american_scientific_journal-766	340	1	[	[	X
american_scientific_journal-766	340	2	19	19	NUM
american_scientific_journal-766	340	3	]	]	PUNCT
american_scientific_journal-766	340	4	martinot	martinot	ADV
american_scientific_journal-766	340	5	-	-	PUNCT
american_scientific_journal-766	340	6	peignoux	peignoux	VERB
american_scientific_journal-766	340	7	m	m	PROPN
american_scientific_journal-766	340	8	,	,	PUNCT
american_scientific_journal-766	340	9	stern	stern	PROPN
american_scientific_journal-766	340	10	c	c	PROPN
american_scientific_journal-766	340	11	,	,	PUNCT
american_scientific_journal-766	340	12	maylin	maylin	PROPN
american_scientific_journal-766	340	13	s	s	PROPN
american_scientific_journal-766	340	14	,	,	PUNCT
american_scientific_journal-766	340	15	ripault	ripault	PROPN
american_scientific_journal-766	340	16	mp	mp	PROPN
american_scientific_journal-766	340	17	,	,	PUNCT
american_scientific_journal-766	340	18	boyer	boyer	PROPN
american_scientific_journal-766	340	19	n	n	CCONJ
american_scientific_journal-766	340	20	,	,	PUNCT
american_scientific_journal-766	340	21	et	et	PROPN
american_scientific_journal-766	340	22	al	al	PROPN
american_scientific_journal-766	340	23	.	.	PROPN
american_scientific_journal-766	340	24	,(2010	,(2010	PROPN
american_scientific_journal-766	340	25	)	)	PUNCT
american_scientific_journal-766	340	26	,	,	PUNCT
american_scientific_journal-766	340	27	twelve	twelve	NUM
american_scientific_journal-766	340	28	weeks	week	NOUN
american_scientific_journal-766	340	29	posttreatment	posttreatment	NOUN
american_scientific_journal-766	340	30	follow	follow	NOUN
american_scientific_journal-766	340	31	-	-	PUNCT
american_scientific_journal-766	340	32	up	up	NOUN
american_scientific_journal-766	340	33	is	be	AUX
american_scientific_journal-766	340	34	as	as	ADV
american_scientific_journal-766	340	35	relevant	relevant	ADJ
american_scientific_journal-766	340	36	as	as	ADP
american_scientific_journal-766	340	37	24	24	NUM
american_scientific_journal-766	340	38	weeks	week	NOUN
american_scientific_journal-766	340	39	to	to	PART
american_scientific_journal-766	340	40	determine	determine	VERB
american_scientific_journal-766	340	41	the	the	DET
american_scientific_journal-766	340	42	sustained	sustained	ADJ
american_scientific_journal-766	340	43	virologic	virologic	ADJ
american_scientific_journal-766	340	44	response	response	NOUN
american_scientific_journal-766	340	45	in	in	ADP
american_scientific_journal-766	340	46	patients	patient	NOUN
american_scientific_journal-766	340	47	with	with	ADP
american_scientific_journal-766	340	48	hepatitis	hepatitis	PROPN
american_scientific_journal-766	340	49	c	c	PROPN
american_scientific_journal-766	340	50	virus	virus	NOUN
american_scientific_journal-766	340	51	receiving	receive	VERB
american_scientific_journal-766	340	52	pegylated	pegylate	VERB
american_scientific_journal-766	340	53	interferon	interferon	NOUN
american_scientific_journal-766	340	54	and	and	CCONJ
american_scientific_journal-766	340	55	ribavirin	ribavirin	NOUN
american_scientific_journal-766	340	56	,	,	PUNCT
american_scientific_journal-766	340	57	hepatology	hepatology	NOUN
american_scientific_journal-766	340	58	,	,	PUNCT
american_scientific_journal-766	340	59	2010	2010	NUM
american_scientific_journal-766	340	60	,	,	PUNCT
american_scientific_journal-766	340	61	51,1122	51,1122	NUM
american_scientific_journal-766	340	62	-	-	SYM
american_scientific_journal-766	340	63	26	26	NUM
american_scientific_journal-766	340	64	.	.	PUNCT
american_scientific_journal-766	341	1	[	[	X
american_scientific_journal-766	341	2	20	20	NUM
american_scientific_journal-766	341	3	]	]	PUNCT
american_scientific_journal-766	341	4	gentile	gentile	NOUN
american_scientific_journal-766	341	5	i	i	PRON
american_scientific_journal-766	341	6	,	,	PUNCT
american_scientific_journal-766	341	7	borgia	borgia	PROPN
american_scientific_journal-766	341	8	f	f	PROPN
american_scientific_journal-766	341	9	,	,	PUNCT
american_scientific_journal-766	341	10	buonomo	buonomo	PROPN
american_scientific_journal-766	341	11	ar	ar	PROPN
american_scientific_journal-766	341	12	,	,	PUNCT
american_scientific_journal-766	341	13	castaldo	castaldo	ADJ
american_scientific_journal-766	341	14	g	g	NOUN
american_scientific_journal-766	341	15	,	,	PUNCT
american_scientific_journal-766	341	16	borgia	borgia	PROPN
american_scientific_journal-766	341	17	g	g	PROPN
american_scientific_journal-766	341	18	,	,	PUNCT
american_scientific_journal-766	341	19	(	(	PUNCT
american_scientific_journal-766	341	20	2013	2013	NUM
american_scientific_journal-766	341	21	)	)	PUNCT
american_scientific_journal-766	341	22	,	,	PUNCT
american_scientific_journal-766	341	23	a	a	DET
american_scientific_journal-766	341	24	novel	novel	NOUN
american_scientific_journal-766	341	25	promising	promise	VERB
american_scientific_journal-766	341	26	therapeutic	therapeutic	ADJ
american_scientific_journal-766	341	27	option	option	NOUN
american_scientific_journal-766	341	28	against	against	ADP
american_scientific_journal-766	341	29	hepatitis	hepatitis	PROPN
american_scientific_journal-766	341	30	c	c	PROPN
american_scientific_journal-766	341	31	virus	virus	PROPN
american_scientific_journal-766	341	32	:	:	PUNCT
american_scientific_journal-766	341	33	an	an	DET
american_scientific_journal-766	341	34	oral	oral	ADJ
american_scientific_journal-766	341	35	nucleotide	nucleotide	NOUN
american_scientific_journal-766	341	36	ns5b	ns5b	ADJ
american_scientific_journal-766	341	37	polymerase	polymerase	NOUN
american_scientific_journal-766	341	38	inhibitor	inhibitor	NOUN
american_scientific_journal-766	341	39	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	341	40	,	,	PUNCT
american_scientific_journal-766	341	41	curr	curr	PROPN
american_scientific_journal-766	341	42	med	med	PROPN
american_scientific_journal-766	341	43	chem	chem	PROPN
american_scientific_journal-766	341	44	,	,	PUNCT
american_scientific_journal-766	341	45	20,3733–42	20,3733–42	PROPN
american_scientific_journal-766	341	46	.	.	PUNCT
american_scientific_journal-766	342	1	[	[	X
american_scientific_journal-766	342	2	21	21	NUM
american_scientific_journal-766	342	3	]	]	X
american_scientific_journal-766	342	4	hoofnagle	hoofnagle	PROPN
american_scientific_journal-766	342	5	jh	jh	PROPN
american_scientific_journal-766	342	6	,	,	PUNCT
american_scientific_journal-766	342	7	mullen	mullen	PROPN
american_scientific_journal-766	342	8	kd	kd	PROPN
american_scientific_journal-766	342	9	,	,	PUNCT
american_scientific_journal-766	342	10	jones	jones	PROPN
american_scientific_journal-766	342	11	db	db	PROPN
american_scientific_journal-766	342	12	,	,	PUNCT
american_scientific_journal-766	342	13	rustgi	rustgi	PROPN
american_scientific_journal-766	342	14	v	v	NOUN
american_scientific_journal-766	342	15	,	,	PUNCT
american_scientific_journal-766	342	16	di	di	X
american_scientific_journal-766	342	17	bisceglie	bisceglie	PROPN
american_scientific_journal-766	342	18	a	a	PROPN
american_scientific_journal-766	342	19	,	,	PUNCT
american_scientific_journal-766	342	20	et	et	PROPN
american_scientific_journal-766	342	21	al	al	PROPN
american_scientific_journal-766	342	22	.	.	PROPN
american_scientific_journal-766	342	23	,(1986	,(1986	PROPN
american_scientific_journal-766	342	24	)	)	PUNCT
american_scientific_journal-766	342	25	,	,	PUNCT
american_scientific_journal-766	342	26	treatment	treatment	NOUN
american_scientific_journal-766	342	27	of	of	ADP
american_scientific_journal-766	342	28	chronic	chronic	ADJ
american_scientific_journal-766	342	29	non	non	NOUN
american_scientific_journal-766	342	30	-	-	ADJ
american_scientific_journal-766	342	31	a	a	ADJ
american_scientific_journal-766	342	32	,	,	PUNCT
american_scientific_journal-766	342	33	non	non	ADJ
american_scientific_journal-766	342	34	-	-	ADJ
american_scientific_journal-766	342	35	b	b	ADJ
american_scientific_journal-766	342	36	hepatitis	hepatitis	NOUN
american_scientific_journal-766	342	37	with	with	ADP
american_scientific_journal-766	342	38	recombinant	recombinant	ADJ
american_scientific_journal-766	342	39	human	human	ADJ
american_scientific_journal-766	342	40	alpha	alpha	NOUN
american_scientific_journal-766	342	41	interferon	interferon	NOUN
american_scientific_journal-766	342	42	,	,	PUNCT
american_scientific_journal-766	342	43	a	a	DET
american_scientific_journal-766	342	44	preliminary	preliminary	ADJ
american_scientific_journal-766	342	45	report	report	NOUN
american_scientific_journal-766	342	46	,	,	PUNCT
american_scientific_journal-766	342	47	n	n	PRON
american_scientific_journal-766	342	48	engl	engl	PROPN
american_scientific_journal-766	342	49	j	j	PROPN
american_scientific_journal-766	342	50	med	med	PROPN
american_scientific_journal-766	342	51	.	.	PROPN
american_scientific_journal-766	342	52	,	,	PUNCT
american_scientific_journal-766	342	53	315,1575–78	315,1575–78	NUM
american_scientific_journal-766	342	54	.	.	PUNCT
american_scientific_journal-766	343	1	[	[	X
american_scientific_journal-766	343	2	22	22	NUM
american_scientific_journal-766	343	3	]	]	X
american_scientific_journal-766	343	4	zeuzem	zeuzem	PROPN
american_scientific_journal-766	343	5	s	s	PROPN
american_scientific_journal-766	343	6	,	,	PUNCT
american_scientific_journal-766	343	7	feinman	feinman	PROPN
american_scientific_journal-766	343	8	sv	sv	PROPN
american_scientific_journal-766	343	9	,	,	PUNCT
american_scientific_journal-766	343	10	rasenack	rasenack	PROPN
american_scientific_journal-766	343	11	j	j	PROPN
american_scientific_journal-766	343	12	,	,	PUNCT
american_scientific_journal-766	343	13	heathcote	heathcote	PROPN
american_scientific_journal-766	343	14	ej	ej	PROPN
american_scientific_journal-766	343	15	,	,	PUNCT
american_scientific_journal-766	343	16	lai	lai	PROPN
american_scientific_journal-766	343	17	,	,	PUNCT
american_scientific_journal-766	343	18	my	my	PRON
american_scientific_journal-766	343	19	,	,	PUNCT
american_scientific_journal-766	343	20	et	et	PROPN
american_scientific_journal-766	343	21	al	al	PROPN
american_scientific_journal-766	343	22	.	.	PROPN
american_scientific_journal-766	343	23	,(2000	,(2000	PROPN
american_scientific_journal-766	343	24	)	)	PUNCT
american_scientific_journal-766	343	25	,	,	PUNCT
american_scientific_journal-766	343	26	peg	peg	NOUN
american_scientific_journal-766	343	27	-	-	PUNCT
american_scientific_journal-766	343	28	interferon	interferon	NOUN
american_scientific_journal-766	343	29	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	343	30	in	in	ADP
american_scientific_journal-766	343	31	patients	patient	NOUN
american_scientific_journal-766	343	32	with	with	ADP
american_scientific_journal-766	343	33	chronic	chronic	ADJ
american_scientific_journal-766	343	34	hepatitis	hepatitis	NOUN
american_scientific_journal-766	343	35	c	c	NOUN
american_scientific_journal-766	343	36	,	,	PUNCT
american_scientific_journal-766	343	37	n	n	PROPN
american_scientific_journal-766	343	38	engl	engl	PROPN
american_scientific_journal-766	343	39	j	j	PROPN
american_scientific_journal-766	343	40	med	med	PROPN
american_scientific_journal-766	343	41	.	.	PROPN
american_scientific_journal-766	343	42	,	,	PUNCT
american_scientific_journal-766	343	43	343(23),1666	343(23),1666	NUM
american_scientific_journal-766	343	44	-	-	SYM
american_scientific_journal-766	343	45	72	72	NUM
american_scientific_journal-766	343	46	.	.	PUNCT
american_scientific_journal-766	344	1	[	[	X
american_scientific_journal-766	344	2	23	23	NUM
american_scientific_journal-766	344	3	]	]	X
american_scientific_journal-766	344	4	heathcote	heathcote	PROPN
american_scientific_journal-766	344	5	ej	ej	PROPN
american_scientific_journal-766	344	6	,	,	PUNCT
american_scientific_journal-766	344	7	shiffman	shiffman	PROPN
american_scientific_journal-766	344	8	ml	ml	PROPN
american_scientific_journal-766	344	9	,	,	PUNCT
american_scientific_journal-766	344	10	cooksley	cooksley	PROPN
american_scientific_journal-766	344	11	wg	wg	PROPN
american_scientific_journal-766	344	12	,	,	PUNCT
american_scientific_journal-766	344	13	dusheiko	dusheiko	PROPN
american_scientific_journal-766	344	14	gm	gm	PROPN
american_scientific_journal-766	344	15	,	,	PUNCT
american_scientific_journal-766	344	16	lee	lee	PROPN
american_scientific_journal-766	344	17	ss	ss	PROPN
american_scientific_journal-766	344	18	,	,	PUNCT
american_scientific_journal-766	344	19	et	et	PROPN
american_scientific_journal-766	344	20	al	al	PROPN
american_scientific_journal-766	344	21	.	.	PROPN
american_scientific_journal-766	344	22	,(2000	,(2000	PROPN
american_scientific_journal-766	344	23	)	)	PUNCT
american_scientific_journal-766	344	24	,	,	PUNCT
american_scientific_journal-766	344	25	peg	peg	NOUN
american_scientific_journal-766	344	26	-	-	PUNCT
american_scientific_journal-766	344	27	interferon	interferon	NOUN
american_scientific_journal-766	344	28	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	344	29	in	in	ADP
american_scientific_journal-766	344	30	patients	patient	NOUN
american_scientific_journal-766	344	31	with	with	ADP
american_scientific_journal-766	344	32	chronic	chronic	ADJ
american_scientific_journal-766	344	33	hepatitis	hepatitis	NOUN
american_scientific_journal-766	344	34	c	c	PROPN
american_scientific_journal-766	344	35	and	and	CCONJ
american_scientific_journal-766	344	36	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	344	37	,	,	PUNCT
american_scientific_journal-766	344	38	n	n	PRON
american_scientific_journal-766	344	39	engl	engl	PROPN
american_scientific_journal-766	344	40	j	j	PROPN
american_scientific_journal-766	344	41	med	med	PROPN
american_scientific_journal-766	344	42	,	,	PUNCT
american_scientific_journal-766	344	43	343(23),1673	343(23),1673	NUM
american_scientific_journal-766	344	44	-	-	PUNCT
american_scientific_journal-766	344	45	80	80	NUM
american_scientific_journal-766	344	46	.	.	PUNCT
american_scientific_journal-766	345	1	[	[	X
american_scientific_journal-766	345	2	24	24	NUM
american_scientific_journal-766	345	3	]	]	PUNCT
american_scientific_journal-766	345	4	fried	fry	VERB
american_scientific_journal-766	345	5	,	,	PUNCT
american_scientific_journal-766	345	6	mw,(2002	mw,(2002	NOUN
american_scientific_journal-766	345	7	)	)	PUNCT
american_scientific_journal-766	345	8	,	,	PUNCT
american_scientific_journal-766	345	9	side	side	NOUN
american_scientific_journal-766	345	10	effects	effect	NOUN
american_scientific_journal-766	345	11	of	of	ADP
american_scientific_journal-766	345	12	therapy	therapy	NOUN
american_scientific_journal-766	345	13	of	of	ADP
american_scientific_journal-766	345	14	hepatitis	hepatitis	PROPN
american_scientific_journal-766	345	15	c	c	PROPN
american_scientific_journal-766	345	16	and	and	CCONJ
american_scientific_journal-766	345	17	their	their	PRON
american_scientific_journal-766	345	18	management.hepatology	management.hepatology	NOUN
american_scientific_journal-766	345	19	,	,	PUNCT
american_scientific_journal-766	345	20	36	36	NUM
american_scientific_journal-766	345	21	,	,	PUNCT
american_scientific_journal-766	345	22	s23744	s23744	PROPN
american_scientific_journal-766	345	23	.	.	PUNCT
american_scientific_journal-766	346	1	[	[	X
american_scientific_journal-766	346	2	25	25	NUM
american_scientific_journal-766	346	3	]	]	PUNCT
american_scientific_journal-766	346	4	ascione	ascione	NOUN
american_scientific_journal-766	346	5	a	a	PRON
american_scientific_journal-766	346	6	,	,	PUNCT
american_scientific_journal-766	346	7	de	de	X
american_scientific_journal-766	346	8	luca	luca	PROPN
american_scientific_journal-766	346	9	m	m	PRON
american_scientific_journal-766	346	10	,	,	PUNCT
american_scientific_journal-766	346	11	tartaglione	tartaglione	PROPN
american_scientific_journal-766	346	12	mt	mt	PROPN
american_scientific_journal-766	346	13	,	,	PUNCT
american_scientific_journal-766	346	14	lampasi	lampasi	PROPN
american_scientific_journal-766	346	15	f	f	PROPN
american_scientific_journal-766	346	16	,	,	PUNCT
american_scientific_journal-766	346	17	di	di	PROPN
american_scientific_journal-766	346	18	-	-	PUNCT
american_scientific_journal-766	346	19	costanzo	costanzo	PROPN
american_scientific_journal-766	346	20	gg	gg	PROPN
american_scientific_journal-766	346	21	,	,	PUNCT
american_scientific_journal-766	346	22	et	et	PROPN
american_scientific_journal-766	346	23	al	al	PROPN
american_scientific_journal-766	346	24	.	.	PROPN
american_scientific_journal-766	346	25	,(2010	,(2010	PROPN
american_scientific_journal-766	346	26	)	)	PUNCT
american_scientific_journal-766	346	27	,	,	PUNCT
american_scientific_journal-766	346	28	peg	peg	NOUN
american_scientific_journal-766	346	29	-	-	PUNCT
american_scientific_journal-766	346	30	interferon	interferon	NOUN
american_scientific_journal-766	346	31	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	346	32	plus	plus	CCONJ
american_scientific_journal-766	346	33	ribavirin	ribavirin	NOUN
american_scientific_journal-766	346	34	is	be	AUX
american_scientific_journal-766	346	35	more	more	ADV
american_scientific_journal-766	346	36	effective	effective	ADJ
american_scientific_journal-766	346	37	than	than	ADP
american_scientific_journal-766	346	38	peg	peg	NOUN
american_scientific_journal-766	346	39	-	-	PUNCT
american_scientific_journal-766	346	40	interferon	interferon	NOUN
american_scientific_journal-766	346	41	alfa-2b	alfa-2b	CCONJ
american_scientific_journal-766	346	42	plus	plus	CCONJ
american_scientific_journal-766	346	43	ribavirin	ribavirin	NOUN
american_scientific_journal-766	346	44	for	for	ADP
american_scientific_journal-766	346	45	treating	treat	VERB
american_scientific_journal-766	346	46	chronic	chronic	ADJ
american_scientific_journal-766	346	47	hepatitis	hepatitis	PROPN
american_scientific_journal-766	346	48	c	c	PROPN
american_scientific_journal-766	346	49	virus	virus	NOUN
american_scientific_journal-766	346	50	infection	infection	NOUN
american_scientific_journal-766	346	51	,	,	PUNCT
american_scientific_journal-766	346	52	gastroenterology	gastroenterology	NOUN
american_scientific_journal-766	346	53	,	,	PUNCT
american_scientific_journal-766	346	54	138(1),116–22	138(1),116–22	NUM
american_scientific_journal-766	346	55	.	.	PUNCT
american_scientific_journal-766	347	1	[	[	X
american_scientific_journal-766	347	2	26	26	NUM
american_scientific_journal-766	347	3	]	]	PUNCT
american_scientific_journal-766	347	4	berenguer	berenguer	PROPN
american_scientific_journal-766	347	5	j	j	PROPN
american_scientific_journal-766	347	6	,	,	PUNCT
american_scientific_journal-766	347	7	lvarez	lvarez	NOUN
american_scientific_journal-766	347	8	-	-	PUNCT
american_scientific_journal-766	347	9	pellicer	pellicer	NOUN
american_scientific_journal-766	347	10	ja	ja	PROPN
american_scientific_journal-766	347	11	,	,	PUNCT
american_scientific_journal-766	347	12	martı´n	martı´n	ADJ
american_scientific_journal-766	347	13	pm	pm	NOUN
american_scientific_journal-766	347	14	,	,	PUNCT
american_scientific_journal-766	347	15	opez	opez	NOUN
american_scientific_journal-766	347	16	-	-	PUNCT
american_scientific_journal-766	347	17	aldeguer	aldeguer	NOUN
american_scientific_journal-766	347	18	il	il	PROPN
american_scientific_journal-766	347	19	,	,	PUNCT
american_scientific_journal-766	347	20	von	von	PROPN
american_scientific_journal-766	347	21	-	-	PUNCT
american_scientific_journal-766	347	22	wichmann	wichmann	PROPN
american_scientific_journal-766	347	23	ma,(2009	ma,(2009	NOUN
american_scientific_journal-766	347	24	)	)	PUNCT
american_scientific_journal-766	347	25	,	,	PUNCT
american_scientific_journal-766	347	26	sustained	sustain	VERB
american_scientific_journal-766	347	27	virological	virological	ADJ
american_scientific_journal-766	347	28	response	response	NOUN
american_scientific_journal-766	347	29	to	to	ADP
american_scientific_journal-766	347	30	interferon	interferon	NOUN
american_scientific_journal-766	347	31	plus	plus	CCONJ
american_scientific_journal-766	347	32	ribavirin	ribavirin	NOUN
american_scientific_journal-766	347	33	reduces	reduce	VERB
american_scientific_journal-766	347	34	liver	liver	NOUN
american_scientific_journal-766	347	35	-	-	PUNCT
american_scientific_journal-766	347	36	related	relate	VERB
american_scientific_journal-766	347	37	complications	complication	NOUN
american_scientific_journal-766	347	38	and	and	CCONJ
american_scientific_journal-766	347	39	mortality	mortality	NOUN
american_scientific_journal-766	347	40	in	in	ADP
american_scientific_journal-766	347	41	patients	patient	NOUN
american_scientific_journal-766	347	42	coinfected	coinfecte	VERB
american_scientific_journal-766	347	43	with	with	ADP
american_scientific_journal-766	347	44	human	human	ADJ
american_scientific_journal-766	347	45	immunodeficiency	immunodeficiency	NOUN
american_scientific_journal-766	347	46	virus	virus	NOUN
american_scientific_journal-766	347	47	and	and	CCONJ
american_scientific_journal-766	347	48	hepatitis	hepatitis	PROPN
american_scientific_journal-766	347	49	c	c	PROPN
american_scientific_journal-766	347	50	virus	virus	PROPN
american_scientific_journal-766	347	51	,	,	PUNCT
american_scientific_journal-766	347	52	18	18	NUM
american_scientific_journal-766	347	53	http://www.ncbi.nlm.nih.gov/pubmed/?term=alexopoulou%20a%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=alexopoulou%20a%5bauth%5d	NOUN
american_scientific_journal-766	347	54	http://www.ncbi.nlm.nih.gov/pubmed/?term=karayiannis%20p%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=karayiannis%20p%5bauth%5d	NOUN
american_scientific_journal-766	347	55	american	american	PROPN
american_scientific_journal-766	347	56	scientific	scientific	PROPN
american_scientific_journal-766	347	57	research	research	NOUN
american_scientific_journal-766	347	58	journal	journal	NOUN
american_scientific_journal-766	347	59	for	for	ADP
american_scientific_journal-766	347	60	engineering	engineering	NOUN
american_scientific_journal-766	347	61	,	,	PUNCT
american_scientific_journal-766	347	62	technology	technology	NOUN
american_scientific_journal-766	347	63	,	,	PUNCT
american_scientific_journal-766	347	64	and	and	CCONJ
american_scientific_journal-766	347	65	sciences	science	NOUN
american_scientific_journal-766	347	66	(	(	PUNCT
american_scientific_journal-766	347	67	asrjets	asrjet	NOUN
american_scientific_journal-766	347	68	)	)	PUNCT
american_scientific_journal-766	347	69	(	(	PUNCT
american_scientific_journal-766	347	70	2015	2015	NUM
american_scientific_journal-766	347	71	)	)	PUNCT
american_scientific_journal-766	347	72	volume	volume	NOUN
american_scientific_journal-766	347	73	13	13	NUM
american_scientific_journal-766	347	74	,	,	PUNCT
american_scientific_journal-766	347	75	no	no	DET
american_scientific_journal-766	347	76	1	1	NUM
american_scientific_journal-766	347	77	,	,	PUNCT
american_scientific_journal-766	347	78	pp	pp	ADV
american_scientific_journal-766	347	79	1	1	NUM
american_scientific_journal-766	347	80	-	-	SYM
american_scientific_journal-766	347	81	23	23	NUM
american_scientific_journal-766	347	82	hepatology	hepatology	NOUN
american_scientific_journal-766	347	83	,	,	PUNCT
american_scientific_journal-766	347	84	50(2),407	50(2),407	NUM
american_scientific_journal-766	347	85	-	-	SYM
american_scientific_journal-766	347	86	13	13	NUM
american_scientific_journal-766	347	87	.	.	PUNCT
american_scientific_journal-766	348	1	(	(	PUNCT
american_scientific_journal-766	348	2	2):407	2):407	NUM
american_scientific_journal-766	348	3	-	-	SYM
american_scientific_journal-766	348	4	4013	4013	NUM
american_scientific_journal-766	348	5	.	.	PUNCT
american_scientific_journal-766	349	1	hepatology	hepatology	NOUN
american_scientific_journal-766	350	1	[	[	X
american_scientific_journal-766	350	2	27	27	NUM
american_scientific_journal-766	350	3	]	]	X
american_scientific_journal-766	350	4	manns	manns	PROPN
american_scientific_journal-766	350	5	mp	mp	PROPN
american_scientific_journal-766	350	6	,	,	PUNCT
american_scientific_journal-766	350	7	mc	mc	PROPN
american_scientific_journal-766	350	8	-	-	PUNCT
american_scientific_journal-766	350	9	hutchison	hutchison	PROPN
american_scientific_journal-766	350	10	jg	jg	PROPN
american_scientific_journal-766	350	11	,	,	PUNCT
american_scientific_journal-766	350	12	gordon	gordon	PROPN
american_scientific_journal-766	350	13	sc,(2001	sc,(2001	PROPN
american_scientific_journal-766	350	14	)	)	PUNCT
american_scientific_journal-766	350	15	,	,	PUNCT
american_scientific_journal-766	350	16	peg	peg	NOUN
american_scientific_journal-766	350	17	-	-	PUNCT
american_scientific_journal-766	350	18	interferon	interferon	NOUN
american_scientific_journal-766	350	19	alfa-2b	alfa-2b	CCONJ
american_scientific_journal-766	350	20	plus	plus	CCONJ
american_scientific_journal-766	350	21	ribavirin	ribavirin	NOUN
american_scientific_journal-766	350	22	compared	compare	VERB
american_scientific_journal-766	350	23	with	with	ADP
american_scientific_journal-766	350	24	interferon	interferon	NOUN
american_scientific_journal-766	350	25	alfa-2b	alfa-2b	CCONJ
american_scientific_journal-766	350	26	plus	plus	CCONJ
american_scientific_journal-766	350	27	ribavirin	ribavirin	NOUN
american_scientific_journal-766	350	28	for	for	ADP
american_scientific_journal-766	350	29	initial	initial	ADJ
american_scientific_journal-766	350	30	treatment	treatment	NOUN
american_scientific_journal-766	350	31	of	of	ADP
american_scientific_journal-766	350	32	chronic	chronic	ADJ
american_scientific_journal-766	350	33	hepatitis	hepatitis	NOUN
american_scientific_journal-766	350	34	c	c	NOUN
american_scientific_journal-766	350	35	:	:	PUNCT
american_scientific_journal-766	350	36	a	a	DET
american_scientific_journal-766	350	37	randomized	randomized	ADJ
american_scientific_journal-766	350	38	trial	trial	NOUN
american_scientific_journal-766	350	39	,	,	PUNCT
american_scientific_journal-766	350	40	lancet	lancet	NOUN
american_scientific_journal-766	350	41	,	,	PUNCT
american_scientific_journal-766	350	42	358,958–65	358,958–65	PROPN
american_scientific_journal-766	350	43	.	.	PUNCT
american_scientific_journal-766	351	1	[	[	X
american_scientific_journal-766	351	2	28	28	NUM
american_scientific_journal-766	351	3	]	]	X
american_scientific_journal-766	351	4	fried	fry	VERB
american_scientific_journal-766	351	5	mw	mw	PROPN
american_scientific_journal-766	351	6	,	,	PUNCT
american_scientific_journal-766	351	7	shiffman	shiffman	PROPN
american_scientific_journal-766	351	8	ml	ml	PROPN
american_scientific_journal-766	351	9	,	,	PUNCT
american_scientific_journal-766	351	10	reddy	reddy	PROPN
american_scientific_journal-766	351	11	kr,(2002	kr,(2002	NOUN
american_scientific_journal-766	351	12	)	)	PUNCT
american_scientific_journal-766	351	13	,	,	PUNCT
american_scientific_journal-766	351	14	peg	peg	NOUN
american_scientific_journal-766	351	15	-	-	PUNCT
american_scientific_journal-766	351	16	interferon	interferon	NOUN
american_scientific_journal-766	351	17	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	351	18	plus	plus	CCONJ
american_scientific_journal-766	351	19	ribavirin	ribavirin	NOUN
american_scientific_journal-766	351	20	for	for	ADP
american_scientific_journal-766	351	21	chronic	chronic	ADJ
american_scientific_journal-766	351	22	hepatitis	hepatitis	PROPN
american_scientific_journal-766	351	23	c	c	PROPN
american_scientific_journal-766	351	24	virus	virus	NOUN
american_scientific_journal-766	351	25	infection	infection	NOUN
american_scientific_journal-766	351	26	,	,	PUNCT
american_scientific_journal-766	351	27	n	n	PROPN
american_scientific_journal-766	351	28	engl	engl	PROPN
american_scientific_journal-766	351	29	j	j	PROPN
american_scientific_journal-766	351	30	med	med	PROPN
american_scientific_journal-766	351	31	,	,	PUNCT
american_scientific_journal-766	351	32	347,975–82	347,975–82	NUM
american_scientific_journal-766	351	33	.	.	PUNCT
american_scientific_journal-766	352	1	[	[	X
american_scientific_journal-766	352	2	29	29	NUM
american_scientific_journal-766	352	3	]	]	X
american_scientific_journal-766	352	4	hadziyannis	hadziyannis	PROPN
american_scientific_journal-766	352	5	sj	sj	PROPN
american_scientific_journal-766	352	6	,	,	PUNCT
american_scientific_journal-766	352	7	sette	sette	PROPN
american_scientific_journal-766	352	8	h	h	PROPN
american_scientific_journal-766	352	9	j	j	PROPN
american_scientific_journal-766	352	10	,	,	PUNCT
american_scientific_journal-766	352	11	morgan	morgan	PROPN
american_scientific_journal-766	352	12	tr	tr	VERB
american_scientific_journal-766	352	13	,	,	PUNCT
american_scientific_journal-766	352	14	(	(	PUNCT
american_scientific_journal-766	352	15	2004),peg	2004),peg	NUM
american_scientific_journal-766	352	16	-	-	PUNCT
american_scientific_journal-766	352	17	interferon	interferon	ADJ
american_scientific_journal-766	352	18	-	-	PUNCT
american_scientific_journal-766	352	19	alpha2a	alpha2a	NOUN
american_scientific_journal-766	352	20	and	and	CCONJ
american_scientific_journal-766	352	21	ribavirin	ribavirin	NOUN
american_scientific_journal-766	352	22	combination	combination	NOUN
american_scientific_journal-766	352	23	therapy	therapy	NOUN
american_scientific_journal-766	352	24	in	in	ADP
american_scientific_journal-766	352	25	chronic	chronic	ADJ
american_scientific_journal-766	352	26	hepatitis	hepatitis	NOUN
american_scientific_journal-766	352	27	c	c	NOUN
american_scientific_journal-766	352	28	:	:	PUNCT
american_scientific_journal-766	352	29	a	a	DET
american_scientific_journal-766	352	30	randomized	randomized	ADJ
american_scientific_journal-766	352	31	study	study	NOUN
american_scientific_journal-766	352	32	of	of	ADP
american_scientific_journal-766	352	33	treatment	treatment	NOUN
american_scientific_journal-766	352	34	duration	duration	NOUN
american_scientific_journal-766	352	35	and	and	CCONJ
american_scientific_journal-766	352	36	ribavirin	ribavirin	NOUN
american_scientific_journal-766	352	37	dose	dose	PROPN
american_scientific_journal-766	352	38	.	.	PUNCT
american_scientific_journal-766	353	1	ann	ann	PROPN
american_scientific_journal-766	353	2	intern	intern	PROPN
american_scientific_journal-766	353	3	med	me	VERB
american_scientific_journal-766	353	4	,	,	PUNCT
american_scientific_journal-766	353	5	140,346–355	140,346–355	NUM
american_scientific_journal-766	353	6	.	.	PUNCT
american_scientific_journal-766	354	1	[	[	X
american_scientific_journal-766	354	2	30	30	NUM
american_scientific_journal-766	354	3	]	]	X
american_scientific_journal-766	354	4	hunyady	hunyady	PROPN
american_scientific_journal-766	354	5	b	b	PROPN
american_scientific_journal-766	354	6	,	,	PUNCT
american_scientific_journal-766	354	7	kovács	kovács	PROPN
american_scientific_journal-766	354	8	b	b	PROPN
american_scientific_journal-766	354	9	,	,	PUNCT
american_scientific_journal-766	354	10	battyáni	battyáni	PROPN
american_scientific_journal-766	354	11	z	z	PROPN
american_scientific_journal-766	354	12	,	,	PUNCT
american_scientific_journal-766	354	13	(	(	PUNCT
american_scientific_journal-766	354	14	2011	2011	NUM
american_scientific_journal-766	354	15	)	)	PUNCT
american_scientific_journal-766	354	16	,	,	PUNCT
american_scientific_journal-766	354	17	side	side	NOUN
american_scientific_journal-766	354	18	-	-	PUNCT
american_scientific_journal-766	354	19	effects	effect	NOUN
american_scientific_journal-766	354	20	of	of	ADP
american_scientific_journal-766	354	21	pegylated	pegylated	ADJ
american_scientific_journal-766	354	22	interferon	interferon	NOUN
american_scientific_journal-766	354	23	plus	plus	CCONJ
american_scientific_journal-766	354	24	ribavirin	ribavirin	NOUN
american_scientific_journal-766	354	25	therapy	therapy	NOUN
american_scientific_journal-766	354	26	with	with	ADP
american_scientific_journal-766	354	27	or	or	CCONJ
american_scientific_journal-766	354	28	without	without	ADP
american_scientific_journal-766	354	29	protease	protease	NOUN
american_scientific_journal-766	354	30	inhibitor	inhibitor	NOUN
american_scientific_journal-766	354	31	direct	direct	ADJ
american_scientific_journal-766	354	32	acting	act	VERB
american_scientific_journal-766	354	33	antiviral	antiviral	ADJ
american_scientific_journal-766	354	34	agents	agent	NOUN
american_scientific_journal-766	354	35	during	during	ADP
american_scientific_journal-766	354	36	treatment	treatment	NOUN
american_scientific_journal-766	354	37	of	of	ADP
american_scientific_journal-766	354	38	chronic	chronic	ADJ
american_scientific_journal-766	354	39	hepatitis	hepatitis	PROPN
american_scientific_journal-766	354	40	c	c	PROPN
american_scientific_journal-766	354	41	virus	virus	NOUN
american_scientific_journal-766	354	42	infection	infection	NOUN
american_scientific_journal-766	354	43	,	,	PUNCT
american_scientific_journal-766	354	44	orv	orv	PROPN
american_scientific_journal-766	354	45	hetil	hetil	PROPN
american_scientific_journal-766	354	46	,	,	PUNCT
american_scientific_journal-766	354	47	152(50),1997	152(50),1997	NUM
american_scientific_journal-766	354	48	-	-	SYM
american_scientific_journal-766	354	49	09	09	NUM
american_scientific_journal-766	354	50	.	.	PUNCT
american_scientific_journal-766	355	1	[	[	X
american_scientific_journal-766	355	2	31	31	NUM
american_scientific_journal-766	355	3	]	]	X
american_scientific_journal-766	355	4	european	european	PROPN
american_scientific_journal-766	355	5	association	association	PROPN
american_scientific_journal-766	355	6	for	for	ADP
american_scientific_journal-766	355	7	the	the	DET
american_scientific_journal-766	355	8	study	study	NOUN
american_scientific_journal-766	355	9	of	of	ADP
american_scientific_journal-766	355	10	the	the	DET
american_scientific_journal-766	355	11	liver	liver	NOUN
american_scientific_journal-766	355	12	(	(	PUNCT
american_scientific_journal-766	355	13	easl),(2011	easl),(2011	X
american_scientific_journal-766	355	14	)	)	PUNCT
american_scientific_journal-766	355	15	,	,	PUNCT
american_scientific_journal-766	355	16	clinical	clinical	ADJ
american_scientific_journal-766	355	17	practice	practice	NOUN
american_scientific_journal-766	355	18	guidelines	guideline	NOUN
american_scientific_journal-766	355	19	:	:	PUNCT
american_scientific_journal-766	355	20	management	management	NOUN
american_scientific_journal-766	355	21	of	of	ADP
american_scientific_journal-766	355	22	hepatitis	hepatitis	PROPN
american_scientific_journal-766	355	23	c	c	PROPN
american_scientific_journal-766	355	24	virus	virus	NOUN
american_scientific_journal-766	355	25	infection	infection	NOUN
american_scientific_journal-766	355	26	,	,	PUNCT
american_scientific_journal-766	355	27	j	j	PROPN
american_scientific_journal-766	355	28	hepatol	hepatol	ADV
american_scientific_journal-766	355	29	,	,	PUNCT
american_scientific_journal-766	355	30	55,245–264	55,245–264	NOUN
american_scientific_journal-766	355	31	.	.	PUNCT
american_scientific_journal-766	356	1	[	[	X
american_scientific_journal-766	356	2	32	32	NUM
american_scientific_journal-766	356	3	]	]	PUNCT
american_scientific_journal-766	356	4	alexopoulou	alexopoulou	NOUN
american_scientific_journal-766	356	5	a	a	PRON
american_scientific_journal-766	356	6	,	,	PUNCT
american_scientific_journal-766	356	7	papatheodoridis	papatheodoridis	PROPN
american_scientific_journal-766	356	8	gv,(2012	gv,(2012	PROPN
american_scientific_journal-766	356	9	)	)	PUNCT
american_scientific_journal-766	356	10	,	,	PUNCT
american_scientific_journal-766	356	11	current	current	ADJ
american_scientific_journal-766	356	12	progress	progress	NOUN
american_scientific_journal-766	356	13	in	in	ADP
american_scientific_journal-766	356	14	the	the	DET
american_scientific_journal-766	356	15	treatment	treatment	NOUN
american_scientific_journal-766	356	16	of	of	ADP
american_scientific_journal-766	356	17	chronic	chronic	ADJ
american_scientific_journal-766	356	18	hepatitis	hepatitis	NOUN
american_scientific_journal-766	356	19	c	c	NOUN
american_scientific_journal-766	356	20	,	,	PUNCT
american_scientific_journal-766	356	21	world	world	PROPN
american_scientific_journal-766	356	22	j	j	PROPN
american_scientific_journal-766	356	23	gastroenterol	gastroenterol	PROPN
american_scientific_journal-766	356	24	,	,	PUNCT
american_scientific_journal-766	356	25	18,6060–69	18,6060–69	PROPN
american_scientific_journal-766	356	26	.	.	PUNCT
american_scientific_journal-766	357	1	[	[	X
american_scientific_journal-766	357	2	33	33	NUM
american_scientific_journal-766	357	3	]	]	PUNCT
american_scientific_journal-766	357	4	anantharamu	anantharamu	NOUN
american_scientific_journal-766	357	5	a	a	PRON
american_scientific_journal-766	357	6	,	,	PUNCT
american_scientific_journal-766	357	7	sharma	sharma	PROPN
american_scientific_journal-766	357	8	s	s	PROPN
american_scientific_journal-766	357	9	,	,	PUNCT
american_scientific_journal-766	357	10	sharma	sharma	PROPN
american_scientific_journal-766	357	11	ak	ak	PROPN
american_scientific_journal-766	357	12	,	,	PUNCT
american_scientific_journal-766	357	13	gupta	gupta	PROPN
american_scientific_journal-766	357	14	ak	ak	PROPN
american_scientific_journal-766	357	15	,	,	PUNCT
american_scientific_journal-766	357	16	dahiya	dahiya	NOUN
american_scientific_journal-766	357	17	n	n	NOUN
american_scientific_journal-766	357	18	,	,	PUNCT
american_scientific_journal-766	357	19	brashier	brashy	ADJ
american_scientific_journal-766	357	20	db,(2014	db,(2014	NOUN
american_scientific_journal-766	357	21	)	)	PUNCT
american_scientific_journal-766	357	22	,	,	PUNCT
american_scientific_journal-766	357	23	a	a	DET
american_scientific_journal-766	357	24	review	review	NOUN
american_scientific_journal-766	357	25	of	of	ADP
american_scientific_journal-766	357	26	the	the	DET
american_scientific_journal-766	357	27	current	current	ADJ
american_scientific_journal-766	357	28	anti	anti	ADJ
american_scientific_journal-766	357	29	-	-	ADJ
american_scientific_journal-766	357	30	hcv	hcv	ADJ
american_scientific_journal-766	357	31	therapy	therapy	NOUN
american_scientific_journal-766	357	32	:	:	PUNCT
american_scientific_journal-766	357	33	are	be	AUX
american_scientific_journal-766	357	34	we	we	PRON
american_scientific_journal-766	357	35	finally	finally	ADV
american_scientific_journal-766	357	36	ready	ready	ADJ
american_scientific_journal-766	357	37	for	for	ADP
american_scientific_journal-766	357	38	interferon	interferon	ADJ
american_scientific_journal-766	357	39	-	-	PUNCT
american_scientific_journal-766	357	40	free	free	ADJ
american_scientific_journal-766	357	41	regimens	regimen	NOUN
american_scientific_journal-766	357	42	,	,	PUNCT
american_scientific_journal-766	357	43	i	i	PRON
american_scientific_journal-766	357	44	j	j	PROPN
american_scientific_journal-766	357	45	of	of	ADP
american_scientific_journal-766	357	46	nutr	nutr	PROPN
american_scientific_journal-766	357	47	pharm	pharm	PROPN
american_scientific_journal-766	357	48	neurolog	neurolog	PROPN
american_scientific_journal-766	357	49	dise	dise	PROPN
american_scientific_journal-766	357	50	,	,	PUNCT
american_scientific_journal-766	357	51	4(5	4(5	PROPN
american_scientific_journal-766	357	52	)	)	PUNCT
american_scientific_journal-766	357	53	,	,	PUNCT
american_scientific_journal-766	357	54	6	6	NUM
american_scientific_journal-766	357	55	-	-	SYM
american_scientific_journal-766	357	56	11	11	NUM
american_scientific_journal-766	357	57	.	.	PUNCT
american_scientific_journal-766	358	1	[	[	X
american_scientific_journal-766	358	2	34	34	NUM
american_scientific_journal-766	358	3	]	]	PUNCT
american_scientific_journal-766	358	4	kayali	kayali	PROPN
american_scientific_journal-766	358	5	z	z	PROPN
american_scientific_journal-766	358	6	,	,	PUNCT
american_scientific_journal-766	358	7	schmidt	schmidt	PROPN
american_scientific_journal-766	358	8	wn	wn	PROPN
american_scientific_journal-766	358	9	,	,	PUNCT
american_scientific_journal-766	358	10	(	(	PUNCT
american_scientific_journal-766	358	11	2014	2014	NUM
american_scientific_journal-766	358	12	)	)	PUNCT
american_scientific_journal-766	358	13	,	,	PUNCT
american_scientific_journal-766	358	14	finally	finally	ADV
american_scientific_journal-766	358	15	sofosbuvir	sofosbuvir	VERB
american_scientific_journal-766	358	16	:	:	PUNCT
american_scientific_journal-766	358	17	an	an	DET
american_scientific_journal-766	358	18	oral	oral	ADJ
american_scientific_journal-766	358	19	anti	anti	ADJ
american_scientific_journal-766	358	20	-	-	ADJ
american_scientific_journal-766	358	21	hcv	hcv	ADJ
american_scientific_journal-766	358	22	drug	drug	NOUN
american_scientific_journal-766	358	23	with	with	ADP
american_scientific_journal-766	358	24	wide	wide	ADJ
american_scientific_journal-766	358	25	performance	performance	NOUN
american_scientific_journal-766	358	26	capability	capability	NOUN
american_scientific_journal-766	358	27	,	,	PUNCT
american_scientific_journal-766	358	28	pharmgenomics	pharmgenomic	NOUN
american_scientific_journal-766	358	29	pers	per	NOUN
american_scientific_journal-766	358	30	med	me	VERB
american_scientific_journal-766	358	31	,	,	PUNCT
american_scientific_journal-766	358	32	7,387–98	7,387–98	PROPN
american_scientific_journal-766	358	33	.	.	PUNCT
american_scientific_journal-766	359	1	[	[	X
american_scientific_journal-766	359	2	35	35	NUM
american_scientific_journal-766	359	3	]	]	X
american_scientific_journal-766	359	4	chatel	chatel	NOUN
american_scientific_journal-766	359	5	-	-	PUNCT
american_scientific_journal-766	359	6	chaix	chaix	NOUN
american_scientific_journal-766	359	7	l	l	NOUN
american_scientific_journal-766	359	8	,	,	PUNCT
american_scientific_journal-766	359	9	baril	baril	NOUN
american_scientific_journal-766	359	10	m	m	PROPN
american_scientific_journal-766	359	11	,	,	PUNCT
american_scientific_journal-766	359	12	lamarre	lamarre	ADJ
american_scientific_journal-766	359	13	d	d	X
american_scientific_journal-766	359	14	,	,	PUNCT
american_scientific_journal-766	359	15	(	(	PUNCT
american_scientific_journal-766	359	16	2010),hepatitis	2010),hepatitis	NUM
american_scientific_journal-766	359	17	c	c	PROPN
american_scientific_journal-766	359	18	virus	virus	NOUN
american_scientific_journal-766	359	19	ns3/4a	ns3/4a	PRON
american_scientific_journal-766	359	20	protease	protease	NOUN
american_scientific_journal-766	359	21	inhibitors	inhibitor	NOUN
american_scientific_journal-766	359	22	:	:	PUNCT
american_scientific_journal-766	359	23	a	a	DET
american_scientific_journal-766	359	24	light	light	NOUN
american_scientific_journal-766	359	25	at	at	ADP
american_scientific_journal-766	359	26	the	the	DET
american_scientific_journal-766	359	27	end	end	NOUN
american_scientific_journal-766	359	28	of	of	ADP
american_scientific_journal-766	359	29	the	the	DET
american_scientific_journal-766	359	30	tunnel	tunnel	NOUN
american_scientific_journal-766	359	31	,	,	PUNCT
american_scientific_journal-766	359	32	viruses	virus	NOUN
american_scientific_journal-766	359	33	,	,	PUNCT
american_scientific_journal-766	359	34	2(8	2(8	NUM
american_scientific_journal-766	359	35	)	)	PUNCT
american_scientific_journal-766	359	36	,	,	PUNCT
american_scientific_journal-766	359	37	1752–65	1752–65	NUM
american_scientific_journal-766	359	38	.	.	PUNCT
american_scientific_journal-766	360	1	[	[	X
american_scientific_journal-766	360	2	36	36	NUM
american_scientific_journal-766	360	3	]	]	X
american_scientific_journal-766	360	4	vaidya	vaidya	PROPN
american_scientific_journal-766	360	5	a	a	X
american_scientific_journal-766	360	6	,	,	PUNCT
american_scientific_journal-766	360	7	perry	perry	PROPN
american_scientific_journal-766	360	8	cm	cm	PROPN
american_scientific_journal-766	360	9	,	,	PUNCT
american_scientific_journal-766	360	10	(	(	PUNCT
american_scientific_journal-766	360	11	2013	2013	NUM
american_scientific_journal-766	360	12	)	)	PUNCT
american_scientific_journal-766	360	13	,	,	PUNCT
american_scientific_journal-766	360	14	simeprevir	simeprevir	NOUN
american_scientific_journal-766	360	15	:	:	PUNCT
american_scientific_journal-766	360	16	first	first	ADJ
american_scientific_journal-766	360	17	global	global	ADJ
american_scientific_journal-766	360	18	approval	approval	NOUN
american_scientific_journal-766	360	19	,	,	PUNCT
american_scientific_journal-766	360	20	drugs	drug	NOUN
american_scientific_journal-766	360	21	,	,	PUNCT
american_scientific_journal-766	360	22	73	73	NUM
american_scientific_journal-766	360	23	(	(	PUNCT
american_scientific_journal-766	360	24	18	18	NUM
american_scientific_journal-766	360	25	)	)	PUNCT
american_scientific_journal-766	360	26	,	,	PUNCT
american_scientific_journal-766	360	27	2093–06	2093–06	NUM
american_scientific_journal-766	360	28	.	.	PUNCT
american_scientific_journal-766	361	1	[	[	X
american_scientific_journal-766	361	2	37	37	NUM
american_scientific_journal-766	361	3	]	]	X
american_scientific_journal-766	361	4	gottwein	gottwein	PROPN
american_scientific_journal-766	361	5	jm	jm	PROPN
american_scientific_journal-766	361	6	,	,	PUNCT
american_scientific_journal-766	361	7	scheel	scheel	PROPN
american_scientific_journal-766	361	8	tk	tk	PROPN
american_scientific_journal-766	361	9	,	,	PUNCT
american_scientific_journal-766	361	10	jensen	jensen	PROPN
american_scientific_journal-766	361	11	tb	tb	PROPN
american_scientific_journal-766	361	12	,	,	PUNCT
american_scientific_journal-766	361	13	ghanem	ghanem	PROPN
american_scientific_journal-766	361	14	l	l	PROPN
american_scientific_journal-766	361	15	,	,	PUNCT
american_scientific_journal-766	361	16	bukh	bukh	PROPN
american_scientific_journal-766	361	17	j	j	PROPN
american_scientific_journal-766	361	18	,	,	PUNCT
american_scientific_journal-766	361	19	(	(	PUNCT
american_scientific_journal-766	361	20	2011	2011	NUM
american_scientific_journal-766	361	21	)	)	PUNCT
american_scientific_journal-766	361	22	,	,	PUNCT
american_scientific_journal-766	361	23	differential	differential	ADJ
american_scientific_journal-766	361	24	efficacy	efficacy	NOUN
american_scientific_journal-766	361	25	of	of	ADP
american_scientific_journal-766	361	26	protease	protease	NOUN
american_scientific_journal-766	361	27	inhibitors	inhibitor	NOUN
american_scientific_journal-766	361	28	against	against	ADP
american_scientific_journal-766	361	29	hcv	hcv	NOUN
american_scientific_journal-766	361	30	genotypes	genotype	NOUN
american_scientific_journal-766	361	31	2a	2a	NUM
american_scientific_journal-766	361	32	,	,	PUNCT
american_scientific_journal-766	361	33	3a	3a	NUM
american_scientific_journal-766	361	34	,	,	PUNCT
american_scientific_journal-766	361	35	5a	5a	NUM
american_scientific_journal-766	361	36	,	,	PUNCT
american_scientific_journal-766	361	37	and	and	CCONJ
american_scientific_journal-766	361	38	6a	6a	NOUN
american_scientific_journal-766	361	39	ns3/4a	ns3/4a	NOUN
american_scientific_journal-766	361	40	protease	protease	NOUN
american_scientific_journal-766	361	41	recombinant	recombinant	ADJ
american_scientific_journal-766	361	42	viruses	virus	NOUN
american_scientific_journal-766	361	43	.	.	PUNCT
american_scientific_journal-766	362	1	astroenterology	astroenterology	NOUN
american_scientific_journal-766	362	2	,	,	PUNCT
american_scientific_journal-766	362	3	141(3),1067	141(3),1067	PROPN
american_scientific_journal-766	362	4	-	-	SYM
american_scientific_journal-766	362	5	79	79	NUM
american_scientific_journal-766	362	6	.	.	PUNCT
american_scientific_journal-766	363	1	[	[	X
american_scientific_journal-766	363	2	38	38	NUM
american_scientific_journal-766	363	3	]	]	PUNCT
american_scientific_journal-766	363	4	us	us	PROPN
american_scientific_journal-766	363	5	food	food	NOUN
american_scientific_journal-766	363	6	and	and	CCONJ
american_scientific_journal-766	363	7	drug	drug	NOUN
american_scientific_journal-766	363	8	administration	administration	NOUN
american_scientific_journal-766	363	9	,	,	PUNCT
american_scientific_journal-766	363	10	simeprevir	simeprevir	PROPN
american_scientific_journal-766	363	11	prescribing	prescribe	VERB
american_scientific_journal-766	363	12	information	information	NOUN
american_scientific_journal-766	363	13	,	,	PUNCT
american_scientific_journal-766	363	14	silver	silver	NOUN
american_scientific_journal-766	363	15	spring	spring	NOUN
american_scientific_journal-766	363	16	,	,	PUNCT
american_scientific_journal-766	363	17	[	[	X
american_scientific_journal-766	363	18	accessed	access	VERB
american_scientific_journal-766	363	19	2014	2014	NUM
american_scientific_journal-766	363	20	may	may	NOUN
american_scientific_journal-766	363	21	5	5	NUM
american_scientific_journal-766	363	22	]	]	PUNCT
american_scientific_journal-766	363	23	,	,	PUNCT
american_scientific_journal-766	363	24	available	available	ADJ
american_scientific_journal-766	363	25	at	at	ADP
american_scientific_journal-766	363	26	:	:	PUNCT
american_scientific_journal-766	363	27	http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/205123s001lbl.pdf	http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/205123s001lbl.pdf	X
american_scientific_journal-766	364	1	[	[	X
american_scientific_journal-766	364	2	39	39	NUM
american_scientific_journal-766	364	3	]	]	X
american_scientific_journal-766	364	4	lawitz	lawitz	NOUN
american_scientific_journal-766	364	5	e	e	NOUN
american_scientific_journal-766	364	6	,	,	PUNCT
american_scientific_journal-766	364	7	sulkowski	sulkowski	PROPN
american_scientific_journal-766	364	8	ms	ms	PROPN
american_scientific_journal-766	364	9	,	,	PUNCT
american_scientific_journal-766	364	10	ghalib	ghalib	PROPN
american_scientific_journal-766	364	11	r	r	PROPN
american_scientific_journal-766	364	12	,	,	PUNCT
american_scientific_journal-766	364	13	rodriguez	rodriguez	NOUN
american_scientific_journal-766	364	14	-	-	PUNCT
american_scientific_journal-766	364	15	torres	torres	PROPN
american_scientific_journal-766	364	16	m	m	PROPN
american_scientific_journal-766	364	17	,	,	PUNCT
american_scientific_journal-766	364	18	younossi	younossi	PROPN
american_scientific_journal-766	364	19	zm	zm	PROPN
american_scientific_journal-766	364	20	,	,	PUNCT
american_scientific_journal-766	364	21	et	et	PROPN
american_scientific_journal-766	364	22	al	al	PROPN
american_scientific_journal-766	364	23	.	.	PROPN
american_scientific_journal-766	364	24	,(2014	,(2014	PROPN
american_scientific_journal-766	364	25	)	)	PUNCT
american_scientific_journal-766	364	26	,	,	PUNCT
american_scientific_journal-766	364	27	simeprevir	simeprevir	PROPN
american_scientific_journal-766	364	28	plus	plus	CCONJ
american_scientific_journal-766	364	29	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	364	30	,	,	PUNCT
american_scientific_journal-766	364	31	with	with	ADP
american_scientific_journal-766	364	32	or	or	CCONJ
american_scientific_journal-766	364	33	without	without	ADP
american_scientific_journal-766	364	34	ribavirin	ribavirin	NOUN
american_scientific_journal-766	364	35	,	,	PUNCT
american_scientific_journal-766	364	36	to	to	PART
american_scientific_journal-766	364	37	treat	treat	VERB
american_scientific_journal-766	364	38	chronic	chronic	ADJ
american_scientific_journal-766	364	39	infection	infection	NOUN
american_scientific_journal-766	364	40	with	with	ADP
american_scientific_journal-766	364	41	hepatitis	hepatitis	PROPN
american_scientific_journal-766	364	42	c	c	PROPN
american_scientific_journal-766	364	43	virus	virus	NOUN
american_scientific_journal-766	364	44	genotype	genotype	NOUN
american_scientific_journal-766	364	45	1	1	NUM
american_scientific_journal-766	364	46	in	in	ADP
american_scientific_journal-766	364	47	non	non	NOUN
american_scientific_journal-766	364	48	-	-	NOUN
american_scientific_journal-766	364	49	responders	responder	NOUN
american_scientific_journal-766	364	50	to	to	PART
american_scientific_journal-766	364	51	pegylated	pegylate	VERB
american_scientific_journal-766	364	52	interferon	interferon	NOUN
american_scientific_journal-766	364	53	and	and	CCONJ
american_scientific_journal-766	364	54	ribavirin	ribavirin	NOUN
american_scientific_journal-766	364	55	and	and	CCONJ
american_scientific_journal-766	364	56	treatment	treatment	NOUN
american_scientific_journal-766	364	57	-	-	PUNCT
american_scientific_journal-766	364	58	naive	naive	ADJ
american_scientific_journal-766	364	59	patients	patient	NOUN
american_scientific_journal-766	364	60	:	:	PUNCT
american_scientific_journal-766	364	61	the	the	DET
american_scientific_journal-766	364	62	cosmos	cosmo	NOUN
american_scientific_journal-766	364	63	randomized	randomize	VERB
american_scientific_journal-766	364	64	study	study	NOUN
american_scientific_journal-766	364	65	,	,	PUNCT
american_scientific_journal-766	364	66	lancet	lancet	PROPN
american_scientific_journal-766	364	67	,	,	PUNCT
american_scientific_journal-766	364	68	384	384	NUM
american_scientific_journal-766	364	69	,	,	PUNCT
american_scientific_journal-766	364	70	1756–65	1756–65	NUM
american_scientific_journal-766	364	71	,	,	PUNCT
american_scientific_journal-766	364	72	[	[	X
american_scientific_journal-766	364	73	40	40	NUM
american_scientific_journal-766	364	74	]	]	PUNCT
american_scientific_journal-766	364	75	asselah	asselah	PROPN
american_scientific_journal-766	364	76	t	t	PROPN
american_scientific_journal-766	364	77	,	,	PUNCT
american_scientific_journal-766	364	78	marcellin	marcellin	PROPN
american_scientific_journal-766	364	79	p	p	PROPN
american_scientific_journal-766	364	80	,	,	PUNCT
american_scientific_journal-766	364	81	(	(	PUNCT
american_scientific_journal-766	364	82	2014	2014	NUM
american_scientific_journal-766	364	83	)	)	PUNCT
american_scientific_journal-766	364	84	,	,	PUNCT
american_scientific_journal-766	364	85	second	second	ADJ
american_scientific_journal-766	364	86	-	-	PUNCT
american_scientific_journal-766	364	87	wave	wave	NOUN
american_scientific_journal-766	364	88	ifn	ifn	NOUN
american_scientific_journal-766	364	89	-	-	PUNCT
american_scientific_journal-766	364	90	based	base	VERB
american_scientific_journal-766	364	91	triple	triple	ADJ
american_scientific_journal-766	364	92	therapy	therapy	NOUN
american_scientific_journal-766	364	93	for	for	ADP
american_scientific_journal-766	364	94	hcv	hcv	NOUN
american_scientific_journal-766	364	95	genotype	genotype	NOUN
american_scientific_journal-766	364	96	1	1	NUM
american_scientific_journal-766	364	97	infection	infection	NOUN
american_scientific_journal-766	364	98	:	:	PUNCT
american_scientific_journal-766	364	99	simeprevir	simeprevir	PROPN
american_scientific_journal-766	364	100	,	,	PUNCT
american_scientific_journal-766	364	101	faldaprevir	faldaprevir	PROPN
american_scientific_journal-766	364	102	and	and	CCONJ
american_scientific_journal-766	364	103	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	364	104	,	,	PUNCT
american_scientific_journal-766	364	105	liver	liver	NOUN
american_scientific_journal-766	364	106	int	int	NOUN
american_scientific_journal-766	364	107	,	,	PUNCT
american_scientific_journal-766	364	108	34	34	NUM
american_scientific_journal-766	364	109	(	(	PUNCT
american_scientific_journal-766	364	110	1	1	NUM
american_scientific_journal-766	364	111	)	)	PUNCT
american_scientific_journal-766	364	112	,	,	PUNCT
american_scientific_journal-766	364	113	60–68	60–68	NUM
american_scientific_journal-766	364	114	.	.	PUNCT
american_scientific_journal-766	365	1	[	[	X
american_scientific_journal-766	365	2	41	41	NUM
american_scientific_journal-766	365	3	]	]	X
american_scientific_journal-766	365	4	sulkowski	sulkowski	PROPN
american_scientific_journal-766	365	5	ms	ms	PROPN
american_scientific_journal-766	365	6	,	,	PUNCT
american_scientific_journal-766	365	7	bourlie`re	bourlie`re	PROPN
american_scientific_journal-766	365	8	m	m	PROPN
american_scientific_journal-766	365	9	,	,	PUNCT
american_scientific_journal-766	365	10	bronowicki	bronowicki	PROPN
american_scientific_journal-766	365	11	gp	gp	NOUN
american_scientific_journal-766	365	12	,	,	PUNCT
american_scientific_journal-766	365	13	asselah	asselah	ADP
american_scientific_journal-766	365	14	t	t	PROPN
american_scientific_journal-766	365	15	,	,	PUNCT
american_scientific_journal-766	365	16	pawlotsky	pawlotsky	ADJ
american_scientific_journal-766	365	17	gm	gm	PROPN
american_scientific_journal-766	365	18	,	,	PUNCT
american_scientific_journal-766	365	19	et	et	PROPN
american_scientific_journal-766	365	20	al	al	PROPN
american_scientific_journal-766	365	21	.	.	PROPN
american_scientific_journal-766	365	22	,(2013),faldaprevir	,(2013),faldaprevir	PUNCT
american_scientific_journal-766	365	23	combined	combine	VERB
american_scientific_journal-766	365	24	with	with	ADP
american_scientific_journal-766	365	25	pegylated	pegylated	ADJ
american_scientific_journal-766	365	26	interferon	interferon	NOUN
american_scientific_journal-766	365	27	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	365	28	and	and	CCONJ
american_scientific_journal-766	365	29	ribavirin	ribavirin	NOUN
american_scientific_journal-766	365	30	in	in	ADP
american_scientific_journal-766	365	31	treatment	treatment	NOUN
american_scientific_journal-766	365	32	-	-	PUNCT
american_scientific_journal-766	365	33	naïve	naïve	ADJ
american_scientific_journal-766	365	34	patients	patient	NOUN
american_scientific_journal-766	365	35	with	with	ADP
american_scientific_journal-766	365	36	chronic	chronic	ADJ
american_scientific_journal-766	365	37	genotype	genotype	NOUN
american_scientific_journal-766	365	38	1	1	NUM
american_scientific_journal-766	365	39	hcv	hcv	NOUN
american_scientific_journal-766	365	40	,	,	PUNCT
american_scientific_journal-766	365	41	silen	silen	ADJ
american_scientific_journal-766	365	42	-	-	PUNCT
american_scientific_journal-766	365	43	c1	c1	NOUN
american_scientific_journal-766	365	44	trial	trial	NOUN
american_scientific_journal-766	365	45	,	,	PUNCT
american_scientific_journal-766	365	46	hepatology	hepatology	NOUN
american_scientific_journal-766	365	47	,	,	PUNCT
american_scientific_journal-766	365	48	57	57	NUM
american_scientific_journal-766	365	49	(	(	PUNCT
american_scientific_journal-766	365	50	6	6	NUM
american_scientific_journal-766	365	51	)	)	PUNCT
american_scientific_journal-766	365	52	,	,	PUNCT
american_scientific_journal-766	365	53	2143–54	2143–54	NUM
american_scientific_journal-766	365	54	.	.	PUNCT
american_scientific_journal-766	366	1	[	[	X
american_scientific_journal-766	366	2	42	42	NUM
american_scientific_journal-766	366	3	]	]	X
american_scientific_journal-766	366	4	kanda	kanda	PROPN
american_scientific_journal-766	366	5	t	t	PROPN
american_scientific_journal-766	366	6	,	,	PUNCT
american_scientific_journal-766	366	7	yokosuka	yokosuka	PROPN
american_scientific_journal-766	366	8	o	o	PROPN
american_scientific_journal-766	366	9	,	,	PUNCT
american_scientific_journal-766	366	10	omata	omata	VERB
american_scientific_journal-766	366	11	m,(2015	m,(2015	PROPN
american_scientific_journal-766	366	12	)	)	PUNCT
american_scientific_journal-766	366	13	,	,	PUNCT
american_scientific_journal-766	366	14	faldaprevir	faldaprevir	NOUN
american_scientific_journal-766	366	15	for	for	ADP
american_scientific_journal-766	366	16	the	the	DET
american_scientific_journal-766	366	17	treatment	treatment	NOUN
american_scientific_journal-766	366	18	of	of	ADP
american_scientific_journal-766	366	19	hepatitis	hepatitis	PROPN
american_scientific_journal-766	366	20	c	c	NOUN
american_scientific_journal-766	366	21	,	,	PUNCT
american_scientific_journal-766	366	22	int	int	PROPN
american_scientific_journal-766	366	23	j	j	PROPN
american_scientific_journal-766	366	24	mol	mol	ADP
american_scientific_journal-766	366	25	sci	sci	PROPN
american_scientific_journal-766	366	26	,	,	PUNCT
american_scientific_journal-766	366	27	16(3),4985	16(3),4985	NUM
american_scientific_journal-766	366	28	-	-	SYM
american_scientific_journal-766	366	29	96	96	NUM
american_scientific_journal-766	366	30	.	.	NOUN
american_scientific_journal-766	366	31	19	19	NUM
american_scientific_journal-766	366	32	http://www.ncbi.nlm.nih.gov/pubmed/?term=hunyady%20b%5bauthor%5d&cauthor=true&cauthor_uid=22112373	http://www.ncbi.nlm.nih.gov/pubmed/?term=hunyady%20b%5bauthor%5d&cauthor=true&cauthor_uid=22112373	PROPN
american_scientific_journal-766	366	33	http://www.ncbi.nlm.nih.gov/pubmed/?term=kov%c3%a1cs%20b%5bauthor%5d&cauthor=true&cauthor_uid=22112373	http://www.ncbi.nlm.nih.gov/pubmed/?term=kov%c3%a1cs%20b%5bauthor%5d&cauthor=true&cauthor_uid=22112373	NOUN
american_scientific_journal-766	366	34	http://www.ncbi.nlm.nih.gov/pubmed/?term=batty%c3%a1ni%20z%5bauthor%5d&cauthor=true&cauthor_uid=22112373	http://www.ncbi.nlm.nih.gov/pubmed/?term=batty%c3%a1ni%20z%5bauthor%5d&cauthor=true&cauthor_uid=22112373	NOUN
american_scientific_journal-766	366	35	http://www.ncbi.nlm.nih.gov/pubmed/22112373	http://www.ncbi.nlm.nih.gov/pubmed/22112373	NUM
american_scientific_journal-766	366	36	http://www.ncbi.nlm.nih.gov/pubmed/?term=kayali%20z%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=kayali%20z%5bauth%5d	PRON
american_scientific_journal-766	366	37	http://www.ncbi.nlm.nih.gov/pubmed/?term=schmidt%20wn%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=schmidt%20wn%5bauth%5d	ADP
american_scientific_journal-766	366	38	http://www.ncbi.nlm.nih.gov/pubmed/?term=chatel-chaix%20l%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=chatel-chaix%20l%5bauth%5d	PROPN
american_scientific_journal-766	366	39	http://www.ncbi.nlm.nih.gov/pubmed/?term=baril%20m%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=baril%20m%5bauth%5d	ADJ
american_scientific_journal-766	366	40	http://www.ncbi.nlm.nih.gov/pubmed/?term=lamarre%20d%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=lamarre%20d%5bauth%5d	NOUN
american_scientific_journal-766	366	41	http://www.ncbi.nlm.nih.gov/pubmed/?term=kanda%20t%5bauthor%5d&cauthor=true&cauthor_uid=25749475	http://www.ncbi.nlm.nih.gov/pubmed/?term=kanda%20t%5bauthor%5d&cauthor=true&cauthor_uid=25749475	PROPN
american_scientific_journal-766	366	42	http://www.ncbi.nlm.nih.gov/pubmed/?term=yokosuka%20o%5bauthor%5d&cauthor=true&cauthor_uid=25749475	http://www.ncbi.nlm.nih.gov/pubmed/?term=yokosuka%20o%5bauthor%5d&cauthor=true&cauthor_uid=25749475	X
american_scientific_journal-766	366	43	http://www.ncbi.nlm.nih.gov/pubmed/?term=omata%20m%5bauthor%5d&cauthor=true&cauthor_uid=25749475	http://www.ncbi.nlm.nih.gov/pubmed/?term=omata%20m%5bauthor%5d&cauthor=true&cauthor_uid=25749475	PROPN
american_scientific_journal-766	366	44	http://www.ncbi.nlm.nih.gov/pubmed/25749475	http://www.ncbi.nlm.nih.gov/pubmed/25749475	PART
american_scientific_journal-766	366	45	american	american	ADJ
american_scientific_journal-766	366	46	scientific	scientific	ADJ
american_scientific_journal-766	366	47	research	research	NOUN
american_scientific_journal-766	366	48	journal	journal	NOUN
american_scientific_journal-766	366	49	for	for	ADP
american_scientific_journal-766	366	50	engineering	engineering	NOUN
american_scientific_journal-766	366	51	,	,	PUNCT
american_scientific_journal-766	366	52	technology	technology	NOUN
american_scientific_journal-766	366	53	,	,	PUNCT
american_scientific_journal-766	366	54	and	and	CCONJ
american_scientific_journal-766	366	55	sciences	science	NOUN
american_scientific_journal-766	366	56	(	(	PUNCT
american_scientific_journal-766	366	57	asrjets	asrjet	NOUN
american_scientific_journal-766	366	58	)	)	PUNCT
american_scientific_journal-766	366	59	(	(	PUNCT
american_scientific_journal-766	366	60	2015	2015	NUM
american_scientific_journal-766	366	61	)	)	PUNCT
american_scientific_journal-766	366	62	volume	volume	NOUN
american_scientific_journal-766	366	63	13	13	NUM
american_scientific_journal-766	366	64	,	,	PUNCT
american_scientific_journal-766	366	65	no	no	DET
american_scientific_journal-766	366	66	1	1	NUM
american_scientific_journal-766	366	67	,	,	PUNCT
american_scientific_journal-766	366	68	pp	pp	ADV
american_scientific_journal-766	366	69	1	1	NUM
american_scientific_journal-766	366	70	-	-	SYM
american_scientific_journal-766	366	71	23	23	NUM
american_scientific_journal-766	367	1	[	[	X
american_scientific_journal-766	367	2	43	43	NUM
american_scientific_journal-766	367	3	]	]	X
american_scientific_journal-766	367	4	mc	mc	PROPN
american_scientific_journal-766	367	5	-	-	PUNCT
american_scientific_journal-766	367	6	phee	phee	PROPN
american_scientific_journal-766	367	7	f	f	PROPN
american_scientific_journal-766	367	8	,	,	PUNCT
american_scientific_journal-766	367	9	hernandez	hernandez	PROPN
american_scientific_journal-766	367	10	d	d	PROPN
american_scientific_journal-766	367	11	,	,	PUNCT
american_scientific_journal-766	367	12	yu	yu	PROPN
american_scientific_journal-766	367	13	f	f	PROPN
american_scientific_journal-766	367	14	,	,	PUNCT
american_scientific_journal-766	367	15	ueland	ueland	PROPN
american_scientific_journal-766	367	16	j	j	PROPN
american_scientific_journal-766	367	17	,	,	PUNCT
american_scientific_journal-766	367	18	monikowski	monikowski	NOUN
american_scientific_journal-766	367	19	a	a	PRON
american_scientific_journal-766	367	20	,	,	PUNCT
american_scientific_journal-766	367	21	et	et	PROPN
american_scientific_journal-766	367	22	al	al	PROPN
american_scientific_journal-766	367	23	.	.	PROPN
american_scientific_journal-766	367	24	,(2013	,(2013	PROPN
american_scientific_journal-766	367	25	)	)	PUNCT
american_scientific_journal-766	367	26	,	,	PUNCT
american_scientific_journal-766	367	27	resistance	resistance	NOUN
american_scientific_journal-766	367	28	analysis	analysis	NOUN
american_scientific_journal-766	367	29	of	of	ADP
american_scientific_journal-766	367	30	hepatitis	hepatitis	PROPN
american_scientific_journal-766	367	31	c	c	PROPN
american_scientific_journal-766	367	32	virus	virus	NOUN
american_scientific_journal-766	367	33	genotype	genotype	NOUN
american_scientific_journal-766	367	34	1	1	NUM
american_scientific_journal-766	367	35	prior	prior	ADJ
american_scientific_journal-766	367	36	treatment	treatment	NOUN
american_scientific_journal-766	367	37	null	null	NOUN
american_scientific_journal-766	367	38	responders	responder	NOUN
american_scientific_journal-766	367	39	receiving	receive	VERB
american_scientific_journal-766	367	40	daclatasvir	daclatasvir	NOUN
american_scientific_journal-766	367	41	and	and	CCONJ
american_scientific_journal-766	367	42	sunaprevir	sunaprevir	PROPN
american_scientific_journal-766	367	43	,	,	PUNCT
american_scientific_journal-766	367	44	hepatology	hepatology	NOUN
american_scientific_journal-766	367	45	,	,	PUNCT
american_scientific_journal-766	367	46	58,902–11	58,902–11	NUM
american_scientific_journal-766	368	1	[	[	X
american_scientific_journal-766	368	2	44	44	NUM
american_scientific_journal-766	368	3	]	]	SYM
american_scientific_journal-766	368	4	marcellin	marcellin	PROPN
american_scientific_journal-766	368	5	p	p	PROPN
american_scientific_journal-766	368	6	,	,	PUNCT
american_scientific_journal-766	368	7	manns	manns	PROPN
american_scientific_journal-766	368	8	mp	mp	PROPN
american_scientific_journal-766	368	9	,	,	PUNCT
american_scientific_journal-766	368	10	janczewska	janczewska	PROPN
american_scientific_journal-766	368	11	e	e	PROPN
american_scientific_journal-766	368	12	,	,	PUNCT
american_scientific_journal-766	368	13	muir	muir	PROPN
american_scientific_journal-766	368	14	aj	aj	PROPN
american_scientific_journal-766	368	15	,	,	PUNCT
american_scientific_journal-766	368	16	wu	wu	PROPN
american_scientific_journal-766	368	17	x	x	PROPN
american_scientific_journal-766	368	18	,	,	PUNCT
american_scientific_journal-766	368	19	trenkle	trenkle	VERB
american_scientific_journal-766	368	20	jd	jd	PROPN
american_scientific_journal-766	368	21	,	,	PUNCT
american_scientific_journal-766	368	22	et	et	PROPN
american_scientific_journal-766	368	23	al	al	PROPN
american_scientific_journal-766	368	24	.	.	PROPN
american_scientific_journal-766	368	25	,	,	PUNCT
american_scientific_journal-766	368	26	(	(	PUNCT
american_scientific_journal-766	368	27	2013	2013	NUM
american_scientific_journal-766	368	28	)	)	PUNCT
american_scientific_journal-766	368	29	,	,	PUNCT
american_scientific_journal-766	368	30	12	12	NUM
american_scientific_journal-766	368	31	weeks	week	NOUN
american_scientific_journal-766	368	32	responseguided	responseguide	VERB
american_scientific_journal-766	368	33	treatment	treatment	NOUN
american_scientific_journal-766	368	34	with	with	ADP
american_scientific_journal-766	368	35	the	the	DET
american_scientific_journal-766	368	36	ns5a	ns5a	ADJ
american_scientific_journal-766	368	37	inhibitor	inhibitor	NOUN
american_scientific_journal-766	368	38	,	,	PUNCT
american_scientific_journal-766	368	39	gs-5885	gs-5885	NOUN
american_scientific_journal-766	368	40	,	,	PUNCT
american_scientific_journal-766	368	41	the	the	DET
american_scientific_journal-766	368	42	ns3	ns3	NOUN
american_scientific_journal-766	368	43	protease	protease	NOUN
american_scientific_journal-766	368	44	inhibitor	inhibitor	NOUN
american_scientific_journal-766	368	45	,	,	PUNCT
american_scientific_journal-766	368	46	gs-9451	gs-9451	NOUN
american_scientific_journal-766	368	47	,	,	PUNCT
american_scientific_journal-766	368	48	plus	plus	CCONJ
american_scientific_journal-766	368	49	pegylated	pegylate	VERB
american_scientific_journal-766	368	50	interferon	interferon	NOUN
american_scientific_journal-766	368	51	and	and	CCONJ
american_scientific_journal-766	368	52	ribavirin	ribavirin	NOUN
american_scientific_journal-766	368	53	in	in	ADP
american_scientific_journal-766	368	54	treatment	treatment	NOUN
american_scientific_journal-766	368	55	naive	naive	ADJ
american_scientific_journal-766	368	56	genotype	genotype	NOUN
american_scientific_journal-766	368	57	1	1	NUM
american_scientific_journal-766	368	58	hepatitis	hepatitis	NOUN
american_scientific_journal-766	368	59	c	c	NOUN
american_scientific_journal-766	368	60	infected	infected	ADJ
american_scientific_journal-766	368	61	patients	patient	NOUN
american_scientific_journal-766	368	62	,	,	PUNCT
american_scientific_journal-766	368	63	j	j	PROPN
american_scientific_journal-766	368	64	hepatol	hepatol	ADJ
american_scientific_journal-766	368	65	.	.	PUNCT
american_scientific_journal-766	369	1	58(2	58(2	NUM
american_scientific_journal-766	369	2	)	)	PUNCT
american_scientific_journal-766	369	3	,	,	PUNCT
american_scientific_journal-766	369	4	s355	s355	PROPN
american_scientific_journal-766	369	5	.	.	PUNCT
american_scientific_journal-766	370	1	[	[	X
american_scientific_journal-766	370	2	45	45	NUM
american_scientific_journal-766	370	3	]	]	PUNCT
american_scientific_journal-766	370	4	vince	vince	NOUN
american_scientific_journal-766	370	5	b	b	PROPN
american_scientific_journal-766	370	6	,	,	PUNCT
american_scientific_journal-766	370	7	hill	hill	PROPN
american_scientific_journal-766	370	8	jm	jm	PROPN
american_scientific_journal-766	370	9	,	,	PUNCT
american_scientific_journal-766	370	10	lawitz	lawitz	PROPN
american_scientific_journal-766	370	11	ej	ej	PROPN
american_scientific_journal-766	370	12	,	,	PUNCT
american_scientific_journal-766	370	13	o’riordan	o’riordan	PROPN
american_scientific_journal-766	370	14	w	w	PROPN
american_scientific_journal-766	370	15	,	,	PUNCT
american_scientific_journal-766	370	16	webster	webster	PROPN
american_scientific_journal-766	370	17	lr	lr	PROPN
american_scientific_journal-766	370	18	,	,	PUNCT
american_scientific_journal-766	370	19	gruener	gruener	PROPN
american_scientific_journal-766	370	20	dm	dm	PROPN
american_scientific_journal-766	370	21	,	,	PUNCT
american_scientific_journal-766	370	22	et	et	PROPN
american_scientific_journal-766	370	23	al	al	PROPN
american_scientific_journal-766	370	24	.	.	PROPN
american_scientific_journal-766	370	25	,(2014	,(2014	PROPN
american_scientific_journal-766	370	26	)	)	PUNCT
american_scientific_journal-766	370	27	,	,	PUNCT
american_scientific_journal-766	370	28	a	a	DET
american_scientific_journal-766	370	29	randomized	randomized	ADJ
american_scientific_journal-766	370	30	,	,	PUNCT
american_scientific_journal-766	370	31	double	double	ADJ
american_scientific_journal-766	370	32	-	-	PUNCT
american_scientific_journal-766	370	33	blind	blind	ADJ
american_scientific_journal-766	370	34	,	,	PUNCT
american_scientific_journal-766	370	35	multiple	multiple	ADJ
american_scientific_journal-766	370	36	-	-	PUNCT
american_scientific_journal-766	370	37	dose	dose	VERB
american_scientific_journal-766	370	38	study	study	NOUN
american_scientific_journal-766	370	39	of	of	ADP
american_scientific_journal-766	370	40	the	the	DET
american_scientific_journal-766	370	41	pan	pan	ADJ
american_scientific_journal-766	370	42	-	-	ADJ
american_scientific_journal-766	370	43	genotypic	genotypic	ADJ
american_scientific_journal-766	370	44	ns5a	ns5a	ADJ
american_scientific_journal-766	370	45	inhibitor	inhibitor	NOUN
american_scientific_journal-766	370	46	samatasvir	samatasvir	NOUN
american_scientific_journal-766	370	47	in	in	ADP
american_scientific_journal-766	370	48	patients	patient	NOUN
american_scientific_journal-766	370	49	infected	infect	VERB
american_scientific_journal-766	370	50	with	with	ADP
american_scientific_journal-766	370	51	hepatitis	hepatitis	PROPN
american_scientific_journal-766	370	52	c	c	PROPN
american_scientific_journal-766	370	53	virus	virus	NOUN
american_scientific_journal-766	370	54	genotype	genotype	NOUN
american_scientific_journal-766	370	55	1	1	NUM
american_scientific_journal-766	370	56	,	,	PUNCT
american_scientific_journal-766	370	57	2	2	NUM
american_scientific_journal-766	370	58	,	,	PUNCT
american_scientific_journal-766	370	59	3	3	NUM
american_scientific_journal-766	370	60	or	or	CCONJ
american_scientific_journal-766	370	61	4	4	NUM
american_scientific_journal-766	370	62	,	,	PUNCT
american_scientific_journal-766	370	63	j	j	PROPN
american_scientific_journal-766	370	64	hepatol	hepatol	ADJ
american_scientific_journal-766	370	65	,	,	PUNCT
american_scientific_journal-766	370	66	60	60	NUM
american_scientific_journal-766	370	67	(	(	PUNCT
american_scientific_journal-766	370	68	5	5	NUM
american_scientific_journal-766	370	69	)	)	PUNCT
american_scientific_journal-766	370	70	,	,	PUNCT
american_scientific_journal-766	370	71	920–27	920–27	PROPN
american_scientific_journal-766	371	1	[	[	X
american_scientific_journal-766	371	2	46	46	NUM
american_scientific_journal-766	371	3	]	]	X
american_scientific_journal-766	371	4	german	german	NOUN
american_scientific_journal-766	371	5	p	p	X
american_scientific_journal-766	371	6	,	,	PUNCT
american_scientific_journal-766	371	7	mathias	mathias	PROPN
american_scientific_journal-766	371	8	a	a	PRON
american_scientific_journal-766	371	9	,	,	PUNCT
american_scientific_journal-766	371	10	pang	pang	NOUN
american_scientific_journal-766	371	11	p	p	X
american_scientific_journal-766	371	12	,	,	PUNCT
american_scientific_journal-766	371	13	yang	yang	PROPN
american_scientific_journal-766	371	14	c	c	PROPN
american_scientific_journal-766	371	15	,	,	PUNCT
american_scientific_journal-766	371	16	yang	yang	PROPN
american_scientific_journal-766	371	17	c	c	PROPN
american_scientific_journal-766	371	18	,	,	PUNCT
american_scientific_journal-766	371	19	han	han	PROPN
american_scientific_journal-766	371	20	l	l	PROPN
american_scientific_journal-766	371	21	,	,	PUNCT
american_scientific_journal-766	371	22	et	et	PROPN
american_scientific_journal-766	371	23	al	al	PROPN
american_scientific_journal-766	371	24	.	.	PROPN
american_scientific_journal-766	371	25	,(2013	,(2013	PROPN
american_scientific_journal-766	371	26	)	)	PUNCT
american_scientific_journal-766	371	27	,	,	PUNCT
american_scientific_journal-766	371	28	healthy	healthy	ADJ
american_scientific_journal-766	371	29	volunteer	volunteer	NOUN
american_scientific_journal-766	371	30	first	first	ADJ
american_scientific_journal-766	371	31	-	-	PUNCT
american_scientific_journal-766	371	32	inhuman	inhuman	ADJ
american_scientific_journal-766	371	33	evaluation	evaluation	NOUN
american_scientific_journal-766	371	34	of	of	ADP
american_scientific_journal-766	371	35	gs-5816	gs-5816	NOUN
american_scientific_journal-766	371	36	,	,	PUNCT
american_scientific_journal-766	371	37	a	a	DET
american_scientific_journal-766	371	38	novel	novel	ADJ
american_scientific_journal-766	371	39	second	second	ADJ
american_scientific_journal-766	371	40	generation	generation	NOUN
american_scientific_journal-766	371	41	broad	broad	ADJ
american_scientific_journal-766	371	42	-	-	PUNCT
american_scientific_journal-766	371	43	genotypic	genotypic	ADJ
american_scientific_journal-766	371	44	ns5a	ns5a	ADJ
american_scientific_journal-766	371	45	inhibitor	inhibitor	NOUN
american_scientific_journal-766	371	46	with	with	ADP
american_scientific_journal-766	371	47	potential	potential	NOUN
american_scientific_journal-766	371	48	for	for	ADP
american_scientific_journal-766	371	49	once	once	ADV
american_scientific_journal-766	371	50	-	-	PUNCT
american_scientific_journal-766	371	51	daily	daily	ADJ
american_scientific_journal-766	371	52	dosing	dosing	NOUN
american_scientific_journal-766	371	53	,	,	PUNCT
american_scientific_journal-766	371	54	in	in	ADP
american_scientific_journal-766	371	55	:	:	PUNCT
american_scientific_journal-766	371	56	abstract	abstract	ADV
american_scientific_journal-766	371	57	presented	present	VERB
american_scientific_journal-766	371	58	at	at	ADP
american_scientific_journal-766	371	59	the	the	DET
american_scientific_journal-766	371	60	48th	48th	ADJ
american_scientific_journal-766	371	61	annual	annual	ADJ
american_scientific_journal-766	371	62	meeting	meeting	NOUN
american_scientific_journal-766	371	63	of	of	ADP
american_scientific_journal-766	371	64	the	the	DET
american_scientific_journal-766	371	65	european	european	PROPN
american_scientific_journal-766	371	66	association	association	PROPN
american_scientific_journal-766	371	67	for	for	ADP
american_scientific_journal-766	371	68	the	the	DET
american_scientific_journal-766	371	69	study	study	NOUN
american_scientific_journal-766	371	70	of	of	ADP
american_scientific_journal-766	371	71	the	the	DET
american_scientific_journal-766	371	72	liver	liver	NOUN
american_scientific_journal-766	371	73	,	,	PUNCT
american_scientific_journal-766	371	74	amsterdam	amsterdam	PROPN
american_scientific_journal-766	371	75	(	(	PUNCT
american_scientific_journal-766	371	76	the	the	DET
american_scientific_journal-766	371	77	netherlands	netherlands	PROPN
american_scientific_journal-766	371	78	)	)	PUNCT
american_scientific_journal-766	371	79	.	.	PUNCT
american_scientific_journal-766	372	1	[	[	X
american_scientific_journal-766	372	2	47	47	NUM
american_scientific_journal-766	372	3	]	]	X
american_scientific_journal-766	372	4	guedj	guedj	PROPN
american_scientific_journal-766	372	5	j	j	PROPN
american_scientific_journal-766	372	6	,	,	PUNCT
american_scientific_journal-766	372	7	dahari	dahari	ADJ
american_scientific_journal-766	372	8	h	h	NOUN
american_scientific_journal-766	372	9	,	,	PUNCT
american_scientific_journal-766	372	10	rong	rong	PROPN
american_scientific_journal-766	372	11	l	l	PROPN
american_scientific_journal-766	372	12	,	,	PUNCT
american_scientific_journal-766	372	13	sansone	sansone	PROPN
american_scientific_journal-766	372	14	nd	nd	PROPN
american_scientific_journal-766	372	15	,	,	PUNCT
american_scientific_journal-766	372	16	nettles	nettle	NOUN
american_scientific_journal-766	372	17	re	re	VERB
american_scientific_journal-766	372	18	,	,	PUNCT
american_scientific_journal-766	372	19	cotler	cotler	NOUN
american_scientific_journal-766	372	20	sj	sj	NOUN
american_scientific_journal-766	372	21	,	,	PUNCT
american_scientific_journal-766	372	22	et	et	PROPN
american_scientific_journal-766	372	23	al	al	PROPN
american_scientific_journal-766	372	24	.	.	PROPN
american_scientific_journal-766	372	25	,(2013	,(2013	PROPN
american_scientific_journal-766	372	26	)	)	PUNCT
american_scientific_journal-766	372	27	,	,	PUNCT
american_scientific_journal-766	372	28	modeling	modeling	NOUN
american_scientific_journal-766	372	29	shows	show	VERB
american_scientific_journal-766	372	30	that	that	SCONJ
american_scientific_journal-766	372	31	the	the	DET
american_scientific_journal-766	372	32	ns5a	ns5a	ADJ
american_scientific_journal-766	372	33	inhibitor	inhibitor	NOUN
american_scientific_journal-766	372	34	daclatasvir	daclatasvir	NOUN
american_scientific_journal-766	372	35	has	have	VERB
american_scientific_journal-766	372	36	two	two	NUM
american_scientific_journal-766	372	37	modes	mode	NOUN
american_scientific_journal-766	372	38	of	of	ADP
american_scientific_journal-766	372	39	action	action	NOUN
american_scientific_journal-766	372	40	and	and	CCONJ
american_scientific_journal-766	372	41	yields	yield	NOUN
american_scientific_journal-766	372	42	a	a	DET
american_scientific_journal-766	372	43	shorter	short	ADJ
american_scientific_journal-766	372	44	estimate	estimate	NOUN
american_scientific_journal-766	372	45	of	of	ADP
american_scientific_journal-766	372	46	the	the	DET
american_scientific_journal-766	372	47	hepatitis	hepatitis	PROPN
american_scientific_journal-766	372	48	c	c	PROPN
american_scientific_journal-766	372	49	virus	virus	NOUN
american_scientific_journal-766	372	50	half	half	ADJ
american_scientific_journal-766	372	51	-	-	PUNCT
american_scientific_journal-766	372	52	life	life	NOUN
american_scientific_journal-766	372	53	,	,	PUNCT
american_scientific_journal-766	372	54	proc	proc	PROPN
american_scientific_journal-766	372	55	natl	natl	PROPN
american_scientific_journal-766	372	56	acad	acad	PROPN
american_scientific_journal-766	372	57	sci	sci	PROPN
american_scientific_journal-766	372	58	usa	usa	PROPN
american_scientific_journal-766	372	59	,	,	PUNCT
american_scientific_journal-766	372	60	110	110	NUM
american_scientific_journal-766	372	61	(	(	PUNCT
american_scientific_journal-766	372	62	10	10	NUM
american_scientific_journal-766	372	63	)	)	PUNCT
american_scientific_journal-766	372	64	,	,	PUNCT
american_scientific_journal-766	372	65	3991–96	3991–96	NUM
american_scientific_journal-766	373	1	[	[	X
american_scientific_journal-766	373	2	48	48	NUM
american_scientific_journal-766	373	3	]	]	PUNCT
american_scientific_journal-766	373	4	suzuki	suzuki	PROPN
american_scientific_journal-766	373	5	f	f	PROPN
american_scientific_journal-766	373	6	,	,	PUNCT
american_scientific_journal-766	373	7	toyota	toyota	PROPN
american_scientific_journal-766	373	8	j	j	PROPN
american_scientific_journal-766	373	9	,	,	PUNCT
american_scientific_journal-766	373	10	ikeda	ikeda	PROPN
american_scientific_journal-766	373	11	k	k	PROPN
american_scientific_journal-766	373	12	,	,	PUNCT
american_scientific_journal-766	373	13	chayama	chayama	PROPN
american_scientific_journal-766	373	14	k	k	NOUN
american_scientific_journal-766	373	15	,	,	PUNCT
american_scientific_journal-766	373	16	mochida	mochida	PROPN
american_scientific_journal-766	373	17	s	s	PROPN
american_scientific_journal-766	373	18	,	,	PUNCT
american_scientific_journal-766	373	19	hayashi	hayashi	PROPN
american_scientific_journal-766	373	20	n	n	CCONJ
american_scientific_journal-766	373	21	,	,	PUNCT
american_scientific_journal-766	373	22	et	et	PROPN
american_scientific_journal-766	373	23	al	al	PROPN
american_scientific_journal-766	373	24	.	.	PROPN
american_scientific_journal-766	373	25	,	,	PUNCT
american_scientific_journal-766	373	26	(	(	PUNCT
american_scientific_journal-766	373	27	2014),a	2014),a	PROPN
american_scientific_journal-766	373	28	randomized	randomize	VERB
american_scientific_journal-766	373	29	trial	trial	NOUN
american_scientific_journal-766	373	30	of	of	ADP
american_scientific_journal-766	373	31	daclatasvir	daclatasvir	NOUN
american_scientific_journal-766	373	32	with	with	ADP
american_scientific_journal-766	373	33	peginterferon	peginterferon	PROPN
american_scientific_journal-766	373	34	alfa-2b	alfa-2b	PRON
american_scientific_journal-766	373	35	and	and	CCONJ
american_scientific_journal-766	373	36	ribavirin	ribavirin	NOUN
american_scientific_journal-766	373	37	for	for	ADP
american_scientific_journal-766	373	38	hcv	hcv	NOUN
american_scientific_journal-766	373	39	genotype	genotype	NOUN
american_scientific_journal-766	373	40	1	1	NUM
american_scientific_journal-766	373	41	infection	infection	NOUN
american_scientific_journal-766	373	42	,	,	PUNCT
american_scientific_journal-766	373	43	antivir	antivir	PROPN
american_scientific_journal-766	373	44	ther	ther	ADV
american_scientific_journal-766	373	45	,	,	PUNCT
american_scientific_journal-766	373	46	19	19	NUM
american_scientific_journal-766	373	47	,	,	PUNCT
american_scientific_journal-766	373	48	,	,	PUNCT
american_scientific_journal-766	373	49	491	491	NUM
american_scientific_journal-766	373	50	–	–	SYM
american_scientific_journal-766	373	51	99	99	NUM
american_scientific_journal-766	374	1	[	[	SYM
american_scientific_journal-766	374	2	49	49	NUM
american_scientific_journal-766	374	3	]	]	X
american_scientific_journal-766	374	4	izumi	izumi	PROPN
american_scientific_journal-766	374	5	n	n	CCONJ
american_scientific_journal-766	374	6	,	,	PUNCT
american_scientific_journal-766	374	7	yokosuka	yokosuka	PROPN
american_scientific_journal-766	374	8	o	o	PROPN
american_scientific_journal-766	374	9	,	,	PUNCT
american_scientific_journal-766	374	10	kawada	kawada	PROPN
american_scientific_journal-766	374	11	n	n	CCONJ
american_scientific_journal-766	374	12	,	,	PUNCT
american_scientific_journal-766	374	13	osaki	osaki	PROPN
american_scientific_journal-766	374	14	y	y	PROPN
american_scientific_journal-766	374	15	,	,	PUNCT
american_scientific_journal-766	374	16	yamamoto	yamamoto	PROPN
american_scientific_journal-766	374	17	k	k	PROPN
american_scientific_journal-766	374	18	,	,	PUNCT
american_scientific_journal-766	374	19	sata	sata	NOUN
american_scientific_journal-766	374	20	m	m	PROPN
american_scientific_journal-766	374	21	,	,	PUNCT
american_scientific_journal-766	374	22	et	et	PROPN
american_scientific_journal-766	374	23	al	al	PROPN
american_scientific_journal-766	374	24	.	.	PROPN
american_scientific_journal-766	374	25	,(2014	,(2014	PROPN
american_scientific_journal-766	374	26	)	)	PUNCT
american_scientific_journal-766	374	27	,	,	PUNCT
american_scientific_journal-766	374	28	daclatasvir	daclatasvir	PROPN
american_scientific_journal-766	374	29	combined	combine	VERB
american_scientific_journal-766	374	30	with	with	ADP
american_scientific_journal-766	374	31	peginterferon	peginterferon	NOUN
american_scientific_journal-766	374	32	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	374	33	and	and	CCONJ
american_scientific_journal-766	374	34	ribavirin	ribavirin	NOUN
american_scientific_journal-766	374	35	in	in	ADP
american_scientific_journal-766	374	36	japanese	japanese	ADJ
american_scientific_journal-766	374	37	patients	patient	NOUN
american_scientific_journal-766	374	38	infected	infect	VERB
american_scientific_journal-766	374	39	with	with	ADP
american_scientific_journal-766	374	40	hepatitis	hepatitis	PROPN
american_scientific_journal-766	374	41	c	c	PROPN
american_scientific_journal-766	374	42	genotype	genotype	NOUN
american_scientific_journal-766	374	43	1	1	NUM
american_scientific_journal-766	374	44	,	,	PUNCT
american_scientific_journal-766	374	45	antivir	antivir	PROPN
american_scientific_journal-766	374	46	ther	ther	ADV
american_scientific_journal-766	374	47	,	,	PUNCT
american_scientific_journal-766	374	48	19,501	19,501	NUM
american_scientific_journal-766	374	49	–	–	SYM
american_scientific_journal-766	374	50	10	10	NUM
american_scientific_journal-766	374	51	[	[	SYM
american_scientific_journal-766	374	52	50	50	NUM
american_scientific_journal-766	374	53	]	]	X
american_scientific_journal-766	374	54	wong	wong	PROPN
american_scientific_journal-766	374	55	ka	ka	PROPN
american_scientific_journal-766	374	56	,	,	PUNCT
american_scientific_journal-766	374	57	worth	worth	ADJ
american_scientific_journal-766	374	58	a	a	PRON
american_scientific_journal-766	374	59	,	,	PUNCT
american_scientific_journal-766	374	60	martin	martin	PROPN
american_scientific_journal-766	374	61	r	r	PROPN
american_scientific_journal-766	374	62	,	,	PUNCT
american_scientific_journal-766	374	63	svarovskaia	svarovskaia	PROPN
american_scientific_journal-766	374	64	e	e	PROPN
american_scientific_journal-766	374	65	,	,	PUNCT
american_scientific_journal-766	374	66	brainard	brainard	PROPN
american_scientific_journal-766	374	67	dm	dm	PROPN
american_scientific_journal-766	374	68	,	,	PUNCT
american_scientific_journal-766	374	69	lawitz	lawitz	PROPN
american_scientific_journal-766	374	70	e	e	NOUN
american_scientific_journal-766	374	71	,	,	PUNCT
american_scientific_journal-766	374	72	et	et	PROPN
american_scientific_journal-766	374	73	al	al	PROPN
american_scientific_journal-766	374	74	.	.	PROPN
american_scientific_journal-766	374	75	,(2013	,(2013	PROPN
american_scientific_journal-766	374	76	)	)	PUNCT
american_scientific_journal-766	374	77	,	,	PUNCT
american_scientific_journal-766	374	78	characterization	characterization	NOUN
american_scientific_journal-766	374	79	of	of	ADP
american_scientific_journal-766	374	80	hepatitis	hepatitis	PROPN
american_scientific_journal-766	374	81	c	c	PROPN
american_scientific_journal-766	374	82	virus	virus	PROPN
american_scientific_journal-766	374	83	resistance	resistance	NOUN
american_scientific_journal-766	374	84	from	from	ADP
american_scientific_journal-766	374	85	a	a	DET
american_scientific_journal-766	374	86	multiple	multiple	ADJ
american_scientific_journal-766	374	87	dose	dose	VERB
american_scientific_journal-766	374	88	clinical	clinical	ADJ
american_scientific_journal-766	374	89	trial	trial	NOUN
american_scientific_journal-766	374	90	of	of	ADP
american_scientific_journal-766	374	91	the	the	DET
american_scientific_journal-766	374	92	novel	novel	ADJ
american_scientific_journal-766	374	93	ns5a	ns5a	PROPN
american_scientific_journal-766	374	94	inhibitor	inhibitor	NOUN
american_scientific_journal-766	374	95	gs-5885	gs-5885	NOUN
american_scientific_journal-766	374	96	antimicrob	antimicrob	PROPN
american_scientific_journal-766	374	97	agents	agents	PROPN
american_scientific_journal-766	374	98	ch	ch	PROPN
american_scientific_journal-766	374	99	,	,	PUNCT
american_scientific_journal-766	374	100	57	57	NUM
american_scientific_journal-766	374	101	(	(	PUNCT
american_scientific_journal-766	374	102	12),6333–40	12),6333–40	NUM
american_scientific_journal-766	374	103	[	[	X
american_scientific_journal-766	374	104	51	51	NUM
american_scientific_journal-766	374	105	]	]	X
american_scientific_journal-766	374	106	lawitz	lawitz	PROPN
american_scientific_journal-766	374	107	ej	ej	PROPN
american_scientific_journal-766	374	108	,	,	PUNCT
american_scientific_journal-766	374	109	gruener	gruener	NOUN
american_scientific_journal-766	374	110	d	d	PROPN
american_scientific_journal-766	374	111	,	,	PUNCT
american_scientific_journal-766	374	112	hill	hill	PROPN
american_scientific_journal-766	374	113	jm	jm	PROPN
american_scientific_journal-766	374	114	,	,	PUNCT
american_scientific_journal-766	374	115	marbury	marbury	PROPN
american_scientific_journal-766	374	116	t	t	PROPN
american_scientific_journal-766	374	117	,	,	PUNCT
american_scientific_journal-766	374	118	moorehead	moorehead	PROPN
american_scientific_journal-766	374	119	l	l	PROPN
american_scientific_journal-766	374	120	,	,	PUNCT
american_scientific_journal-766	374	121	mathias	mathias	PROPN
american_scientific_journal-766	374	122	,	,	PUNCT
american_scientific_journal-766	374	123	a	a	PRON
american_scientific_journal-766	374	124	,	,	PUNCT
american_scientific_journal-766	374	125	et	et	PROPN
american_scientific_journal-766	374	126	al	al	PROPN
american_scientific_journal-766	374	127	.	.	PROPN
american_scientific_journal-766	374	128	,	,	PUNCT
american_scientific_journal-766	374	129	(	(	PUNCT
american_scientific_journal-766	374	130	2012	2012	NUM
american_scientific_journal-766	374	131	)	)	PUNCT
american_scientific_journal-766	374	132	,	,	PUNCT
american_scientific_journal-766	374	133	a	a	DET
american_scientific_journal-766	374	134	phase	phase	NOUN
american_scientific_journal-766	374	135	1	1	NUM
american_scientific_journal-766	374	136	,	,	PUNCT
american_scientific_journal-766	374	137	randomized	randomize	VERB
american_scientific_journal-766	374	138	,	,	PUNCT
american_scientific_journal-766	374	139	placebo	placebo	NOUN
american_scientific_journal-766	374	140	-	-	PUNCT
american_scientific_journal-766	374	141	controlled	control	VERB
american_scientific_journal-766	374	142	,	,	PUNCT
american_scientific_journal-766	374	143	3	3	NUM
american_scientific_journal-766	374	144	-	-	PUNCT
american_scientific_journal-766	374	145	day	day	NOUN
american_scientific_journal-766	374	146	,	,	PUNCT
american_scientific_journal-766	374	147	dose	dose	NOUN
american_scientific_journal-766	374	148	-	-	PUNCT
american_scientific_journal-766	374	149	ranging	range	VERB
american_scientific_journal-766	374	150	study	study	NOUN
american_scientific_journal-766	374	151	of	of	ADP
american_scientific_journal-766	374	152	gs-5885	gs-5885	PROPN
american_scientific_journal-766	374	153	,	,	PUNCT
american_scientific_journal-766	374	154	an	an	DET
american_scientific_journal-766	374	155	ns5a	ns5a	ADJ
american_scientific_journal-766	374	156	inhibitor	inhibitor	NOUN
american_scientific_journal-766	374	157	,	,	PUNCT
american_scientific_journal-766	374	158	in	in	ADP
american_scientific_journal-766	374	159	patients	patient	NOUN
american_scientific_journal-766	374	160	with	with	ADP
american_scientific_journal-766	374	161	genotype	genotype	NOUN
american_scientific_journal-766	374	162	1	1	NUM
american_scientific_journal-766	374	163	hepatitis	hepatitis	NOUN
american_scientific_journal-766	374	164	c	c	NOUN
american_scientific_journal-766	374	165	,	,	PUNCT
american_scientific_journal-766	374	166	j	j	PROPN
american_scientific_journal-766	374	167	hepatol	hepatol	ADJ
american_scientific_journal-766	374	168	,	,	PUNCT
american_scientific_journal-766	374	169	57	57	NUM
american_scientific_journal-766	374	170	(	(	PUNCT
american_scientific_journal-766	374	171	1	1	NUM
american_scientific_journal-766	374	172	)	)	PUNCT
american_scientific_journal-766	374	173	,	,	PUNCT
american_scientific_journal-766	375	1	24–31	24–31	NUM
american_scientific_journal-766	375	2	[	[	SYM
american_scientific_journal-766	375	3	52	52	NUM
american_scientific_journal-766	375	4	]	]	X
american_scientific_journal-766	375	5	flisiak	flisiak	PROPN
american_scientific_journal-766	375	6	r	r	PROPN
american_scientific_journal-766	375	7	,	,	PUNCT
american_scientific_journal-766	375	8	pawlotsky	pawlotsky	ADJ
american_scientific_journal-766	375	9	jm	jm	PROPN
american_scientific_journal-766	375	10	,	,	PUNCT
american_scientific_journal-766	375	11	crabbe	crabbe	NOUN
american_scientific_journal-766	375	12	r	r	PROPN
american_scientific_journal-766	375	13	,	,	PUNCT
american_scientific_journal-766	375	14	calistru	calistru	NOUN
american_scientific_journal-766	375	15	pi	pi	PROPN
american_scientific_journal-766	375	16	,	,	PUNCT
american_scientific_journal-766	375	17	kryczka	kryczka	PROPN
american_scientific_journal-766	375	18	w	w	PROPN
american_scientific_journal-766	375	19	,	,	PUNCT
american_scientific_journal-766	375	20	et	et	PROPN
american_scientific_journal-766	375	21	al	al	PROPN
american_scientific_journal-766	375	22	.	.	PROPN
american_scientific_journal-766	375	23	,(2011	,(2011	PUNCT
american_scientific_journal-766	375	24	)	)	PUNCT
american_scientific_journal-766	375	25	,	,	PUNCT
american_scientific_journal-766	375	26	once	once	ADV
american_scientific_journal-766	375	27	-	-	PUNCT
american_scientific_journal-766	375	28	daily	daily	ADJ
american_scientific_journal-766	375	29	alisporivir	alisporivir	NOUN
american_scientific_journal-766	375	30	(	(	PUNCT
american_scientific_journal-766	375	31	deb025	deb025	PROPN
american_scientific_journal-766	375	32	)	)	PUNCT
american_scientific_journal-766	375	33	plus	plus	CCONJ
american_scientific_journal-766	375	34	peginterferon	peginterferon	PROPN
american_scientific_journal-766	375	35	alfa-2a	alfa-2a	PROPN
american_scientific_journal-766	375	36	/	/	SYM
american_scientific_journal-766	375	37	ribavirin	ribavirin	NOUN
american_scientific_journal-766	375	38	results	result	NOUN
american_scientific_journal-766	375	39	in	in	ADP
american_scientific_journal-766	375	40	superior	superior	ADJ
american_scientific_journal-766	375	41	sustained	sustain	VERB
american_scientific_journal-766	375	42	virologic	virologic	ADJ
american_scientific_journal-766	375	43	response	response	NOUN
american_scientific_journal-766	375	44	in	in	ADP
american_scientific_journal-766	375	45	chronic	chronic	ADJ
american_scientific_journal-766	375	46	hepatitis	hepatitis	NOUN
american_scientific_journal-766	375	47	c	c	PROPN
american_scientific_journal-766	375	48	genotype	genotype	NOUN
american_scientific_journal-766	375	49	1	1	NUM
american_scientific_journal-766	375	50	treatment	treatment	NOUN
american_scientific_journal-766	375	51	-	-	PUNCT
american_scientific_journal-766	375	52	naive	naive	ADJ
american_scientific_journal-766	375	53	patients	patient	NOUN
american_scientific_journal-766	375	54	,	,	PUNCT
american_scientific_journal-766	375	55	j	j	PROPN
american_scientific_journal-766	375	56	hepatol	hepatol	ADJ
american_scientific_journal-766	375	57	,	,	PUNCT
american_scientific_journal-766	375	58	54(1	54(1	NUM
american_scientific_journal-766	375	59	)	)	PUNCT
american_scientific_journal-766	375	60	,	,	PUNCT
american_scientific_journal-766	375	61	s2	s2	NOUN
american_scientific_journal-766	375	62	[	[	PUNCT
american_scientific_journal-766	375	63	53	53	NUM
american_scientific_journal-766	375	64	]	]	X
american_scientific_journal-766	375	65	koch	koch	PROPN
american_scientific_journal-766	375	66	,	,	PUNCT
american_scientific_journal-766	375	67	u	u	PROPN
american_scientific_journal-766	375	68	,	,	PUNCT
american_scientific_journal-766	375	69	narjes	narje	NOUN
american_scientific_journal-766	375	70	,	,	PUNCT
american_scientific_journal-766	375	71	f,(2007	f,(2007	ADJ
american_scientific_journal-766	375	72	)	)	PUNCT
american_scientific_journal-766	375	73	,	,	PUNCT
american_scientific_journal-766	375	74	recent	recent	ADJ
american_scientific_journal-766	375	75	progress	progress	NOUN
american_scientific_journal-766	375	76	in	in	ADP
american_scientific_journal-766	375	77	the	the	DET
american_scientific_journal-766	375	78	development	development	NOUN
american_scientific_journal-766	375	79	of	of	ADP
american_scientific_journal-766	375	80	inhibitors	inhibitor	NOUN
american_scientific_journal-766	375	81	of	of	ADP
american_scientific_journal-766	375	82	the	the	DET
american_scientific_journal-766	375	83	hepatitis	hepatitis	PROPN
american_scientific_journal-766	375	84	c	c	PROPN
american_scientific_journal-766	375	85	virus	virus	PROPN
american_scientific_journal-766	375	86	rna	rna	NOUN
american_scientific_journal-766	375	87	-	-	PUNCT
american_scientific_journal-766	375	88	dependent	dependent	ADJ
american_scientific_journal-766	375	89	rna	rna	NOUN
american_scientific_journal-766	375	90	polymerase	polymerase	NOUN
american_scientific_journal-766	375	91	,	,	PUNCT
american_scientific_journal-766	375	92	curr	curr	X
american_scientific_journal-766	375	93	top	top	ADJ
american_scientific_journal-766	375	94	med	med	ADJ
american_scientific_journal-766	375	95	chem	chem	NOUN
american_scientific_journal-766	375	96	,	,	PUNCT
american_scientific_journal-766	375	97	7(13),1302	7(13),1302	NUM
american_scientific_journal-766	375	98	-	-	SYM
american_scientific_journal-766	375	99	29	29	NUM
american_scientific_journal-766	375	100	.	.	PUNCT
american_scientific_journal-766	376	1	[	[	X
american_scientific_journal-766	376	2	54	54	NUM
american_scientific_journal-766	376	3	]	]	X
american_scientific_journal-766	376	4	kwong	kwong	NOUN
american_scientific_journal-766	376	5	ad	ad	NOUN
american_scientific_journal-766	376	6	,	,	PUNCT
american_scientific_journal-766	376	7	mcnair	mcnair	PROPN
american_scientific_journal-766	376	8	l	l	PROPN
american_scientific_journal-766	376	9	,	,	PUNCT
american_scientific_journal-766	376	10	jacobson	jacobson	PROPN
american_scientific_journal-766	376	11	i	i	PRON
american_scientific_journal-766	376	12	,	,	PUNCT
american_scientific_journal-766	376	13	george	george	PROPN
american_scientific_journal-766	376	14	s	s	PROPN
american_scientific_journal-766	376	15	,	,	PUNCT
american_scientific_journal-766	376	16	(	(	PUNCT
american_scientific_journal-766	376	17	2008),recent	2008),recent	NUM
american_scientific_journal-766	376	18	progress	progress	NOUN
american_scientific_journal-766	376	19	in	in	ADP
american_scientific_journal-766	376	20	the	the	DET
american_scientific_journal-766	376	21	development	development	NOUN
american_scientific_journal-766	376	22	of	of	ADP
american_scientific_journal-766	376	23	selected	select	VERB
american_scientific_journal-766	376	24	hepatitis	hepatitis	PROPN
american_scientific_journal-766	376	25	c	c	PROPN
american_scientific_journal-766	376	26	virus	virus	NOUN
american_scientific_journal-766	376	27	ns3.4a	ns3.4a	CCONJ
american_scientific_journal-766	376	28	protease	protease	NOUN
american_scientific_journal-766	376	29	and	and	CCONJ
american_scientific_journal-766	376	30	ns5b	ns5b	ADJ
american_scientific_journal-766	376	31	polymerase	polymerase	NOUN
american_scientific_journal-766	376	32	inhibitors	inhibitor	NOUN
american_scientific_journal-766	376	33	,	,	PUNCT
american_scientific_journal-766	376	34	curr	curr	PROPN
american_scientific_journal-766	376	35	opin	opin	NOUN
american_scientific_journal-766	376	36	pharmacol	pharmacol	PROPN
american_scientific_journal-766	376	37	,	,	PUNCT
american_scientific_journal-766	376	38	8,522–31	8,522–31	PROPN
american_scientific_journal-766	376	39	.	.	PUNCT
american_scientific_journal-766	377	1	[	[	X
american_scientific_journal-766	377	2	55	55	NUM
american_scientific_journal-766	377	3	]	]	SYM
american_scientific_journal-766	377	4	belkacem	belkacem	ADJ
american_scientific_journal-766	377	5	aa	aa	NOUN
american_scientific_journal-766	377	6	,	,	PUNCT
american_scientific_journal-766	377	7	guichou	guichou	PROPN
american_scientific_journal-766	377	8	jf	jf	PROPN
american_scientific_journal-766	377	9	,	,	PUNCT
american_scientific_journal-766	377	10	brillet	brillet	NOUN
american_scientific_journal-766	377	11	r	r	NOUN
american_scientific_journal-766	377	12	,	,	PUNCT
american_scientific_journal-766	377	13	ahnou	ahnou	ADJ
american_scientific_journal-766	377	14	n	n	CCONJ
american_scientific_journal-766	377	15	,	,	PUNCT
american_scientific_journal-766	377	16	hernandez	hernandez	PROPN
american_scientific_journal-766	377	17	e	e	PROPN
american_scientific_journal-766	377	18	,	,	PUNCT
american_scientific_journal-766	377	19	et	et	PROPN
american_scientific_journal-766	377	20	al	al	PROPN
american_scientific_journal-766	377	21	.	.	PROPN
american_scientific_journal-766	377	22	,(2014	,(2014	PROPN
american_scientific_journal-766	377	23	)	)	PUNCT
american_scientific_journal-766	377	24	,	,	PUNCT
american_scientific_journal-766	377	25	inhibition	inhibition	NOUN
american_scientific_journal-766	377	26	of	of	ADP
american_scientific_journal-766	377	27	rna	rna	NOUN
american_scientific_journal-766	377	28	binding	bind	VERB
american_scientific_journal-766	377	29	to	to	ADP
american_scientific_journal-766	377	30	hepatitis	hepatitis	PROPN
american_scientific_journal-766	377	31	c	c	PROPN
american_scientific_journal-766	377	32	virus	virus	PROPN
american_scientific_journal-766	377	33	rna	rna	NOUN
american_scientific_journal-766	377	34	-	-	PUNCT
american_scientific_journal-766	377	35	dependent	dependent	ADJ
american_scientific_journal-766	377	36	rna	rna	NOUN
american_scientific_journal-766	377	37	polymerase	polymerase	NOUN
american_scientific_journal-766	377	38	:	:	PUNCT
american_scientific_journal-766	377	39	a	a	DET
american_scientific_journal-766	377	40	new	new	ADJ
american_scientific_journal-766	377	41	mechanism	mechanism	NOUN
american_scientific_journal-766	377	42	for	for	ADP
american_scientific_journal-766	377	43	antiviral	antiviral	ADJ
american_scientific_journal-766	377	44	intervention	intervention	NOUN
american_scientific_journal-766	377	45	,	,	PUNCT
american_scientific_journal-766	377	46	nucl	nucl	PROPN
american_scientific_journal-766	377	47	acids	acid	NOUN
american_scientific_journal-766	377	48	res	re	NOUN
american_scientific_journal-766	377	49	,	,	PUNCT
american_scientific_journal-766	377	50	42	42	NUM
american_scientific_journal-766	377	51	(	(	PUNCT
american_scientific_journal-766	377	52	14	14	NUM
american_scientific_journal-766	377	53	)	)	PUNCT
american_scientific_journal-766	377	54	,	,	PUNCT
american_scientific_journal-766	377	55	9399	9399	NUM
american_scientific_journal-766	377	56	-	-	SYM
american_scientific_journal-766	377	57	09	09	NUM
american_scientific_journal-766	377	58	.	.	PUNCT
american_scientific_journal-766	378	1	[	[	X
american_scientific_journal-766	378	2	56	56	NUM
american_scientific_journal-766	378	3	]	]	X
american_scientific_journal-766	378	4	legrand	legrand	PROPN
american_scientific_journal-766	378	5	-	-	PUNCT
american_scientific_journal-766	378	6	abravanel	abravanel	PROPN
american_scientific_journal-766	378	7	f	f	PROPN
american_scientific_journal-766	378	8	,	,	PUNCT
american_scientific_journal-766	378	9	nicot	nicot	PROPN
american_scientific_journal-766	378	10	f	f	PROPN
american_scientific_journal-766	378	11	,	,	PUNCT
american_scientific_journal-766	378	12	izopet	izopet	PROPN
american_scientific_journal-766	378	13	j	j	PROPN
american_scientific_journal-766	378	14	,	,	PUNCT
american_scientific_journal-766	378	15	(	(	PUNCT
american_scientific_journal-766	378	16	2010	2010	NUM
american_scientific_journal-766	378	17	)	)	PUNCT
american_scientific_journal-766	378	18	,	,	PUNCT
american_scientific_journal-766	378	19	new	new	ADJ
american_scientific_journal-766	378	20	ns5b	ns5b	ADJ
american_scientific_journal-766	378	21	polymerase	polymerase	NOUN
american_scientific_journal-766	378	22	inhibitors	inhibitor	NOUN
american_scientific_journal-766	378	23	for	for	ADP
american_scientific_journal-766	378	24	hepatitis	hepatitis	PROPN
american_scientific_journal-766	378	25	20	20	NUM
american_scientific_journal-766	378	26	american	american	ADJ
american_scientific_journal-766	378	27	scientific	scientific	ADJ
american_scientific_journal-766	378	28	research	research	NOUN
american_scientific_journal-766	378	29	journal	journal	NOUN
american_scientific_journal-766	378	30	for	for	ADP
american_scientific_journal-766	378	31	engineering	engineering	NOUN
american_scientific_journal-766	378	32	,	,	PUNCT
american_scientific_journal-766	378	33	technology	technology	NOUN
american_scientific_journal-766	378	34	,	,	PUNCT
american_scientific_journal-766	378	35	and	and	CCONJ
american_scientific_journal-766	378	36	sciences	science	NOUN
american_scientific_journal-766	378	37	(	(	PUNCT
american_scientific_journal-766	378	38	asrjets	asrjet	NOUN
american_scientific_journal-766	378	39	)	)	PUNCT
american_scientific_journal-766	378	40	(	(	PUNCT
american_scientific_journal-766	378	41	2015	2015	NUM
american_scientific_journal-766	378	42	)	)	PUNCT
american_scientific_journal-766	378	43	volume	volume	NOUN
american_scientific_journal-766	378	44	13	13	NUM
american_scientific_journal-766	378	45	,	,	PUNCT
american_scientific_journal-766	378	46	no	no	DET
american_scientific_journal-766	378	47	1	1	NUM
american_scientific_journal-766	378	48	,	,	PUNCT
american_scientific_journal-766	378	49	pp	pp	ADV
american_scientific_journal-766	378	50	1	1	NUM
american_scientific_journal-766	378	51	-	-	SYM
american_scientific_journal-766	378	52	23	23	NUM
american_scientific_journal-766	378	53	c	c	NOUN
american_scientific_journal-766	378	54	,	,	PUNCT
american_scientific_journal-766	378	55	expert	expert	ADJ
american_scientific_journal-766	378	56	opin	opin	NOUN
american_scientific_journal-766	378	57	invest	invest	NOUN
american_scientific_journal-766	378	58	drugs	drug	NOUN
american_scientific_journal-766	378	59	,	,	PUNCT
american_scientific_journal-766	378	60	19,963	19,963	NUM
american_scientific_journal-766	378	61	-	-	SYM
american_scientific_journal-766	378	62	75	75	NUM
american_scientific_journal-766	378	63	[	[	SYM
american_scientific_journal-766	378	64	57	57	NUM
american_scientific_journal-766	378	65	]	]	PUNCT
american_scientific_journal-766	378	66	trivella	trivella	NOUN
american_scientific_journal-766	378	67	jp1	jp1	PROPN
american_scientific_journal-766	378	68	,	,	PUNCT
american_scientific_journal-766	378	69	gutierrez	gutierrez	PROPN
american_scientific_journal-766	378	70	j	j	PROPN
american_scientific_journal-766	378	71	,	,	PUNCT
american_scientific_journal-766	378	72	martin	martin	PROPN
american_scientific_journal-766	378	73	p,(2015	p,(2015	PROPN
american_scientific_journal-766	378	74	)	)	PUNCT
american_scientific_journal-766	378	75	,	,	PUNCT
american_scientific_journal-766	378	76	dasabuvir	dasabuvir	PROPN
american_scientific_journal-766	378	77	:	:	PUNCT
american_scientific_journal-766	378	78	a	a	DET
american_scientific_journal-766	378	79	new	new	ADJ
american_scientific_journal-766	378	80	direct	direct	ADJ
american_scientific_journal-766	378	81	antiviral	antiviral	ADJ
american_scientific_journal-766	378	82	agent	agent	NOUN
american_scientific_journal-766	378	83	for	for	ADP
american_scientific_journal-766	378	84	the	the	DET
american_scientific_journal-766	378	85	treatment	treatment	NOUN
american_scientific_journal-766	378	86	of	of	ADP
american_scientific_journal-766	378	87	hepatitis	hepatitis	PROPN
american_scientific_journal-766	378	88	c	c	NOUN
american_scientific_journal-766	378	89	,	,	PUNCT
american_scientific_journal-766	378	90	expert	expert	ADJ
american_scientific_journal-766	378	91	opin	opin	NOUN
american_scientific_journal-766	378	92	pharmacother	pharmacother	NOUN
american_scientific_journal-766	378	93	,	,	PUNCT
american_scientific_journal-766	378	94	16(4),617	16(4),617	NUM
american_scientific_journal-766	378	95	-	-	SYM
american_scientific_journal-766	378	96	24	24	NUM
american_scientific_journal-766	378	97	.	.	PUNCT
american_scientific_journal-766	379	1	[	[	X
american_scientific_journal-766	379	2	58	58	NUM
american_scientific_journal-766	379	3	]	]	X
american_scientific_journal-766	379	4	pawlotsky	pawlotsky	ADJ
american_scientific_journal-766	379	5	jm1,(2013	jm1,(2013	PROPN
american_scientific_journal-766	379	6	)	)	PUNCT
american_scientific_journal-766	379	7	,	,	PUNCT
american_scientific_journal-766	379	8	ns5a	ns5a	VERB
american_scientific_journal-766	379	9	inhibitors	inhibitor	NOUN
american_scientific_journal-766	379	10	in	in	ADP
american_scientific_journal-766	379	11	the	the	DET
american_scientific_journal-766	379	12	treatment	treatment	NOUN
american_scientific_journal-766	379	13	of	of	ADP
american_scientific_journal-766	379	14	hepatitis	hepatitis	PROPN
american_scientific_journal-766	379	15	c	c	PROPN
american_scientific_journal-766	379	16	,	,	PUNCT
american_scientific_journal-766	379	17	j	j	PROPN
american_scientific_journal-766	379	18	hepatol	hepatol	ADJ
american_scientific_journal-766	379	19	,	,	PUNCT
american_scientific_journal-766	379	20	59(2),375	59(2),375	NUM
american_scientific_journal-766	379	21	-	-	SYM
american_scientific_journal-766	379	22	82	82	NUM
american_scientific_journal-766	379	23	.	.	PUNCT
american_scientific_journal-766	380	1	[	[	X
american_scientific_journal-766	380	2	59	59	NUM
american_scientific_journal-766	380	3	]	]	PUNCT
american_scientific_journal-766	380	4	hassanein	hassanein	PROPN
american_scientific_journal-766	380	5	t	t	PROPN
american_scientific_journal-766	380	6	,	,	PUNCT
american_scientific_journal-766	380	7	lawitz	lawitz	PROPN
american_scientific_journal-766	380	8	e	e	PROPN
american_scientific_journal-766	380	9	,	,	PUNCT
american_scientific_journal-766	380	10	crespo	crespo	PROPN
american_scientific_journal-766	380	11	i	i	PRON
american_scientific_journal-766	380	12	,	,	PUNCT
american_scientific_journal-766	380	13	davis	davis	PROPN
american_scientific_journal-766	380	14	m	m	PROPN
american_scientific_journal-766	380	15	,	,	PUNCT
american_scientific_journal-766	380	16	demicco	demicco	PROPN
american_scientific_journal-766	380	17	mp	mp	PROPN
american_scientific_journal-766	380	18	,	,	PUNCT
american_scientific_journal-766	380	19	nelson	nelson	PROPN
american_scientific_journal-766	380	20	dr	dr	PROPN
american_scientific_journal-766	380	21	,	,	PUNCT
american_scientific_journal-766	380	22	et	et	PROPN
american_scientific_journal-766	380	23	al	al	PROPN
american_scientific_journal-766	380	24	.	.	PROPN
american_scientific_journal-766	380	25	,(2012	,(2012	PROPN
american_scientific_journal-766	380	26	)	)	PUNCT
american_scientific_journal-766	380	27	,	,	PUNCT
american_scientific_journal-766	380	28	once	once	ADV
american_scientific_journal-766	380	29	daily	daily	ADV
american_scientific_journal-766	380	30	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	380	31	(	(	PUNCT
american_scientific_journal-766	380	32	gs-7977	gs-7977	PROPN
american_scientific_journal-766	380	33	)	)	PUNCT
american_scientific_journal-766	380	34	plus	plus	CCONJ
american_scientific_journal-766	380	35	peg	peg	NOUN
american_scientific_journal-766	380	36	/	/	SYM
american_scientific_journal-766	380	37	rbv	rbv	NOUN
american_scientific_journal-766	380	38	:	:	PUNCT
american_scientific_journal-766	380	39	high	high	ADJ
american_scientific_journal-766	380	40	early	early	ADJ
american_scientific_journal-766	380	41	response	response	NOUN
american_scientific_journal-766	380	42	rates	rate	NOUN
american_scientific_journal-766	380	43	are	be	AUX
american_scientific_journal-766	380	44	maintained	maintain	VERB
american_scientific_journal-766	380	45	during	during	ADP
american_scientific_journal-766	380	46	post	post	ADJ
american_scientific_journal-766	380	47	-	-	ADJ
american_scientific_journal-766	380	48	treatment	treatment	ADJ
american_scientific_journal-766	380	49	follow	follow	NOUN
american_scientific_journal-766	380	50	-	-	PUNCT
american_scientific_journal-766	380	51	up	up	NOUN
american_scientific_journal-766	380	52	in	in	ADP
american_scientific_journal-766	380	53	treatment	treatment	NOUN
american_scientific_journal-766	380	54	-	-	PUNCT
american_scientific_journal-766	380	55	naive	naive	ADJ
american_scientific_journal-766	380	56	patients	patient	NOUN
american_scientific_journal-766	380	57	with	with	ADP
american_scientific_journal-766	380	58	hcv	hcv	NOUN
american_scientific_journal-766	380	59	genotype	genotype	NOUN
american_scientific_journal-766	380	60	1	1	NUM
american_scientific_journal-766	380	61	,	,	PUNCT
american_scientific_journal-766	380	62	4	4	NUM
american_scientific_journal-766	380	63	,	,	PUNCT
american_scientific_journal-766	380	64	and	and	CCONJ
american_scientific_journal-766	380	65	6	6	NUM
american_scientific_journal-766	380	66	infections	infection	NOUN
american_scientific_journal-766	380	67	in	in	ADP
american_scientific_journal-766	380	68	the	the	DET
american_scientific_journal-766	380	69	atomic	atomic	ADJ
american_scientific_journal-766	380	70	study	study	NOUN
american_scientific_journal-766	380	71	,	,	PUNCT
american_scientific_journal-766	380	72	hepatology	hepatology	NOUN
american_scientific_journal-766	380	73	,	,	PUNCT
american_scientific_journal-766	380	74	56	56	NUM
american_scientific_journal-766	380	75	,	,	PUNCT
american_scientific_journal-766	380	76	307a	307a	PROPN
american_scientific_journal-766	380	77	[	[	X
american_scientific_journal-766	380	78	60	60	NUM
american_scientific_journal-766	380	79	]	]	X
american_scientific_journal-766	380	80	mathias	mathias	PROPN
american_scientific_journal-766	380	81	ma	ma	PROPN
american_scientific_journal-766	380	82	,	,	PUNCT
american_scientific_journal-766	380	83	cornpropst	cornpropst	NOUN
american_scientific_journal-766	380	84	d	d	PROPN
american_scientific_journal-766	380	85	,	,	PUNCT
american_scientific_journal-766	380	86	clemons	clemons	PROPN
american_scientific_journal-766	380	87	j	j	PROPN
american_scientific_journal-766	380	88	,	,	PUNCT
american_scientific_journal-766	380	89	denning	den	VERB
american_scientific_journal-766	380	90	wt,(2012	wt,(2012	NOUN
american_scientific_journal-766	380	91	)	)	PUNCT
american_scientific_journal-766	380	92	,	,	PUNCT
american_scientific_journal-766	380	93	no	no	DET
american_scientific_journal-766	380	94	clinically	clinically	ADV
american_scientific_journal-766	380	95	significant	significant	ADJ
american_scientific_journal-766	380	96	pharmacokinetic	pharmacokinetic	ADJ
american_scientific_journal-766	380	97	drug	drug	NOUN
american_scientific_journal-766	380	98	–	–	PUNCT
american_scientific_journal-766	380	99	drug	drug	NOUN
american_scientific_journal-766	380	100	interactions	interaction	NOUN
american_scientific_journal-766	380	101	between	between	ADP
american_scientific_journal-766	380	102	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	380	103	(	(	PUNCT
american_scientific_journal-766	380	104	gs-7977	gs-7977	PROPN
american_scientific_journal-766	380	105	)	)	PUNCT
american_scientific_journal-766	380	106	and	and	CCONJ
american_scientific_journal-766	380	107	the	the	DET
american_scientific_journal-766	380	108	immunosuppressants	immunosuppressant	NOUN
american_scientific_journal-766	380	109	,	,	PUNCT
american_scientific_journal-766	380	110	cyclosporine	cyclosporine	VERB
american_scientific_journal-766	380	111	a	a	PRON
american_scientific_journal-766	380	112	or	or	CCONJ
american_scientific_journal-766	380	113	tacrolimus	tacrolimus	NOUN
american_scientific_journal-766	380	114	in	in	ADP
american_scientific_journal-766	380	115	healthy	healthy	ADJ
american_scientific_journal-766	380	116	volunteers	volunteer	NOUN
american_scientific_journal-766	380	117	,	,	PUNCT
american_scientific_journal-766	380	118	hepatology	hepatology	NOUN
american_scientific_journal-766	380	119	,	,	PUNCT
american_scientific_journal-766	380	120	56	56	NUM
american_scientific_journal-766	380	121	,	,	PUNCT
american_scientific_journal-766	380	122	1063a–64a	1063a–64a	NUM
american_scientific_journal-766	381	1	[	[	X
american_scientific_journal-766	381	2	61	61	NUM
american_scientific_journal-766	381	3	]	]	PUNCT
american_scientific_journal-766	381	4	ron	ron	PROPN
american_scientific_journal-766	381	5	w,"gilead	w,"gilead	PROPN
american_scientific_journal-766	381	6	’s	’s	PART
american_scientific_journal-766	381	7	hcv	hcv	PROPN
american_scientific_journal-766	381	8	drug	drug	NOUN
american_scientific_journal-766	381	9	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	381	10	approved	approve	VERB
american_scientific_journal-766	381	11	by	by	ADP
american_scientific_journal-766	381	12	the	the	DET
american_scientific_journal-766	381	13	fda	fda	PROPN
american_scientific_journal-766	381	14	but	but	CCONJ
american_scientific_journal-766	381	15	accessible	accessible	ADJ
american_scientific_journal-766	381	16	for	for	ADP
american_scientific_journal-766	381	17	how	how	SCONJ
american_scientific_journal-766	381	18	many	many	ADJ
american_scientific_journal-766	381	19	?	?	PUNCT
american_scientific_journal-766	381	20	"	"	PUNCT
american_scientific_journal-766	381	21	.	.	PUNCT
american_scientific_journal-766	382	1	doctors	doctor	NOUN
american_scientific_journal-766	382	2	of	of	ADP
american_scientific_journal-766	382	3	the	the	DET
american_scientific_journal-766	382	4	world	world	NOUN
american_scientific_journal-766	382	5	,	,	PUNCT
american_scientific_journal-766	382	6	2014	2014	NUM
american_scientific_journal-766	382	7	.	.	PUNCT
american_scientific_journal-766	383	1	[	[	X
american_scientific_journal-766	383	2	62	62	NUM
american_scientific_journal-766	383	3	]	]	X
american_scientific_journal-766	383	4	wodak	wodak	PROPN
american_scientific_journal-766	383	5	a	a	PRON
american_scientific_journal-766	383	6	,	,	PUNCT
american_scientific_journal-766	383	7	an	an	DET
american_scientific_journal-766	383	8	overview	overview	NOUN
american_scientific_journal-766	383	9	of	of	ADP
american_scientific_journal-766	383	10	hepatitis	hepatitis	PROPN
american_scientific_journal-766	383	11	c	c	NOUN
american_scientific_journal-766	383	12	;	;	PUNCT
american_scientific_journal-766	383	13	clinical	clinical	ADJ
american_scientific_journal-766	383	14	management	management	NOUN
american_scientific_journal-766	383	15	in	in	ADP
american_scientific_journal-766	383	16	opiate	opiate	ADJ
american_scientific_journal-766	383	17	pharmacotherapy	pharmacotherapy	NOUN
american_scientific_journal-766	383	18	settings	setting	VERB
american_scientific_journal-766	383	19	australian	australian	ADJ
american_scientific_journal-766	383	20	society	society	NOUN
american_scientific_journal-766	383	21	for	for	ADP
american_scientific_journal-766	383	22	hiv	hiv	PROPN
american_scientific_journal-766	383	23	medicine	medicine	PROPN
american_scientific_journal-766	383	24	inc	inc	PROPN
american_scientific_journal-766	383	25	(	(	PUNCT
american_scientific_journal-766	383	26	ashm	ashm	PROPN
american_scientific_journal-766	383	27	)	)	PUNCT
american_scientific_journal-766	383	28	,	,	PUNCT
american_scientific_journal-766	383	29	national	national	ADJ
american_scientific_journal-766	383	30	viral	viral	ADJ
american_scientific_journal-766	383	31	hepatitis	hepatitis	NOUN
american_scientific_journal-766	383	32	education	education	NOUN
american_scientific_journal-766	383	33	program	program	NOUN
american_scientific_journal-766	383	34	,	,	PUNCT
american_scientific_journal-766	383	35	2009,1	2009,1	PROPN
american_scientific_journal-766	383	36	-	-	PUNCT
american_scientific_journal-766	383	37	4	4	NUM
american_scientific_journal-766	383	38	.	.	PUNCT
american_scientific_journal-766	384	1	[	[	X
american_scientific_journal-766	384	2	63	63	NUM
american_scientific_journal-766	384	3	]	]	X
american_scientific_journal-766	384	4	smith	smith	PROPN
american_scientific_journal-766	384	5	mw	mw	PROPN
american_scientific_journal-766	384	6	,	,	PUNCT
american_scientific_journal-766	384	7	walters	walters	PROPN
american_scientific_journal-766	384	8	ka	ka	PROPN
american_scientific_journal-766	384	9	,	,	PUNCT
american_scientific_journal-766	384	10	korth	korth	PROPN
american_scientific_journal-766	384	11	mj	mj	PROPN
american_scientific_journal-766	384	12	,	,	PUNCT
american_scientific_journal-766	384	13	fitzgibbon	fitzgibbon	PROPN
american_scientific_journal-766	384	14	m	m	PROPN
american_scientific_journal-766	384	15	,	,	PUNCT
american_scientific_journal-766	384	16	proll	proll	NOUN
american_scientific_journal-766	384	17	s	s	PROPN
american_scientific_journal-766	384	18	,	,	PUNCT
american_scientific_journal-766	384	19	thompson	thompson	PROPN
american_scientific_journal-766	384	20	jc	jc	PROPN
american_scientific_journal-766	384	21	,	,	PUNCT
american_scientific_journal-766	384	22	et	et	PROPN
american_scientific_journal-766	384	23	al	al	PROPN
american_scientific_journal-766	384	24	.	.	PROPN
american_scientific_journal-766	384	25	,(2006	,(2006	PUNCT
american_scientific_journal-766	384	26	)	)	PUNCT
american_scientific_journal-766	384	27	,	,	PUNCT
american_scientific_journal-766	384	28	gene	gene	NOUN
american_scientific_journal-766	384	29	expression	expression	NOUN
american_scientific_journal-766	384	30	patterns	pattern	NOUN
american_scientific_journal-766	384	31	that	that	PRON
american_scientific_journal-766	384	32	correlate	correlate	VERB
american_scientific_journal-766	384	33	with	with	ADP
american_scientific_journal-766	384	34	hepatitis	hepatitis	PROPN
american_scientific_journal-766	384	35	c	c	PROPN
american_scientific_journal-766	384	36	and	and	CCONJ
american_scientific_journal-766	384	37	early	early	ADJ
american_scientific_journal-766	384	38	progression	progression	NOUN
american_scientific_journal-766	384	39	to	to	ADP
american_scientific_journal-766	384	40	fibrosis	fibrosis	NOUN
american_scientific_journal-766	384	41	in	in	ADP
american_scientific_journal-766	384	42	liver	liver	NOUN
american_scientific_journal-766	384	43	transplant	transplant	NOUN
american_scientific_journal-766	384	44	recipients	recipient	NOUN
american_scientific_journal-766	384	45	,	,	PUNCT
american_scientific_journal-766	384	46	gastroenterology	gastroenterology	NOUN
american_scientific_journal-766	384	47	,	,	PUNCT
american_scientific_journal-766	384	48	130,179–87	130,179–87	NUM
american_scientific_journal-766	384	49	.	.	PUNCT
american_scientific_journal-766	385	1	[	[	X
american_scientific_journal-766	385	2	64	64	NUM
american_scientific_journal-766	385	3	]	]	PUNCT
american_scientific_journal-766	385	4	fung	fung	PROPN
american_scientific_journal-766	385	5	a	a	X
american_scientific_journal-766	385	6	,	,	PUNCT
american_scientific_journal-766	385	7	jin	jin	PROPN
american_scientific_journal-766	385	8	z	z	PROPN
american_scientific_journal-766	385	9	,	,	PUNCT
american_scientific_journal-766	385	10	dyatkina	dyatkina	NOUN
american_scientific_journal-766	385	11	n	n	CCONJ
american_scientific_journal-766	385	12	,	,	PUNCT
american_scientific_journal-766	385	13	wang	wang	PROPN
american_scientific_journal-766	385	14	g	g	PROPN
american_scientific_journal-766	385	15	,	,	PUNCT
american_scientific_journal-766	385	16	beigelman	beigelman	PROPN
american_scientific_journal-766	385	17	l	l	NOUN
american_scientific_journal-766	385	18	,	,	PUNCT
american_scientific_journal-766	385	19	deval	deval	PROPN
american_scientific_journal-766	385	20	j	j	PROPN
american_scientific_journal-766	385	21	,	,	PUNCT
american_scientific_journal-766	385	22	(	(	PUNCT
american_scientific_journal-766	385	23	2014	2014	NUM
american_scientific_journal-766	385	24	)	)	PUNCT
american_scientific_journal-766	385	25	,	,	PUNCT
american_scientific_journal-766	385	26	efficiency	efficiency	NOUN
american_scientific_journal-766	385	27	of	of	ADP
american_scientific_journal-766	385	28	incorporation	incorporation	NOUN
american_scientific_journal-766	385	29	and	and	CCONJ
american_scientific_journal-766	385	30	chain	chain	NOUN
american_scientific_journal-766	385	31	termination	termination	NOUN
american_scientific_journal-766	385	32	determines	determine	VERB
american_scientific_journal-766	385	33	the	the	DET
american_scientific_journal-766	385	34	inhibition	inhibition	NOUN
american_scientific_journal-766	385	35	potency	potency	NOUN
american_scientific_journal-766	385	36	of	of	ADP
american_scientific_journal-766	385	37	2'-modified	2'-modified	ADJ
american_scientific_journal-766	385	38	nucleotide	nucleotide	ADJ
american_scientific_journal-766	385	39	analogs	analog	NOUN
american_scientific_journal-766	385	40	against	against	ADP
american_scientific_journal-766	385	41	hepatitis	hepatitis	PROPN
american_scientific_journal-766	385	42	c	c	PROPN
american_scientific_journal-766	385	43	virus	virus	NOUN
american_scientific_journal-766	385	44	polymerase	polymerase	NOUN
american_scientific_journal-766	385	45	,	,	PUNCT
american_scientific_journal-766	385	46	antimicrobial	antimicrobial	ADJ
american_scientific_journal-766	385	47	agents	agent	NOUN
american_scientific_journal-766	385	48	and	and	CCONJ
american_scientific_journal-766	385	49	chemotherapy	chemotherapy	NOUN
american_scientific_journal-766	385	50	,	,	PUNCT
american_scientific_journal-766	385	51	58	58	NUM
american_scientific_journal-766	385	52	(	(	PUNCT
american_scientific_journal-766	385	53	7	7	NUM
american_scientific_journal-766	385	54	)	)	PUNCT
american_scientific_journal-766	385	55	,	,	PUNCT
american_scientific_journal-766	385	56	3636–45	3636–45	NUM
american_scientific_journal-766	385	57	.	.	PUNCT
american_scientific_journal-766	386	1	[	[	X
american_scientific_journal-766	386	2	65	65	NUM
american_scientific_journal-766	386	3	]	]	X
american_scientific_journal-766	386	4	lam	lam	PROPN
american_scientific_journal-766	386	5	am	am	PROPN
american_scientific_journal-766	386	6	,	,	PUNCT
american_scientific_journal-766	386	7	espiritu	espiritu	PROPN
american_scientific_journal-766	386	8	c	c	PROPN
american_scientific_journal-766	386	9	,	,	PUNCT
american_scientific_journal-766	386	10	bansal	bansal	NOUN
american_scientific_journal-766	386	11	s	s	PROPN
american_scientific_journal-766	386	12	,	,	PUNCT
american_scientific_journal-766	386	13	micolochick	micolochick	PROPN
american_scientific_journal-766	386	14	-	-	PUNCT
american_scientific_journal-766	386	15	steuer	steuer	PROPN
american_scientific_journal-766	386	16	hm	hm	PROPN
american_scientific_journal-766	386	17	,	,	PUNCT
american_scientific_journal-766	386	18	niu	niu	PROPN
american_scientific_journal-766	386	19	c	c	PROPN
american_scientific_journal-766	386	20	,	,	PUNCT
american_scientific_journal-766	386	21	zennou	zennou	NOUN
american_scientific_journal-766	386	22	v	v	NOUN
american_scientific_journal-766	386	23	,	,	PUNCT
american_scientific_journal-766	386	24	et	et	PROPN
american_scientific_journal-766	386	25	al	al	PROPN
american_scientific_journal-766	386	26	.	.	PROPN
american_scientific_journal-766	386	27	,(2012	,(2012	PROPN
american_scientific_journal-766	386	28	)	)	PUNCT
american_scientific_journal-766	386	29	,	,	PUNCT
american_scientific_journal-766	386	30	genotype	genotype	NOUN
american_scientific_journal-766	386	31	and	and	CCONJ
american_scientific_journal-766	386	32	subtype	subtype	VERB
american_scientific_journal-766	386	33	pro	pro	ADJ
american_scientific_journal-766	386	34	-	-	ADJ
american_scientific_journal-766	386	35	ling	ling	ADJ
american_scientific_journal-766	386	36	of	of	ADP
american_scientific_journal-766	386	37	psi-7977	psi-7977	NOUN
american_scientific_journal-766	386	38	as	as	ADP
american_scientific_journal-766	386	39	a	a	DET
american_scientific_journal-766	386	40	nucleotide	nucleotide	ADJ
american_scientific_journal-766	386	41	inhibitor	inhibitor	NOUN
american_scientific_journal-766	386	42	of	of	ADP
american_scientific_journal-766	386	43	hepatitis	hepatitis	PROPN
american_scientific_journal-766	386	44	c	c	PROPN
american_scientific_journal-766	386	45	virus	virus	PROPN
american_scientific_journal-766	386	46	,	,	PUNCT
american_scientific_journal-766	386	47	antimicrob	antimicrob	PROPN
american_scientific_journal-766	386	48	agents	agents	PROPN
american_scientific_journal-766	386	49	chemother	chemother	PROPN
american_scientific_journal-766	386	50	,	,	PUNCT
american_scientific_journal-766	386	51	56,3359	56,3359	PROPN
american_scientific_journal-766	386	52	-	-	SYM
american_scientific_journal-766	386	53	68	68	NUM
american_scientific_journal-766	386	54	.	.	PUNCT
american_scientific_journal-766	387	1	[	[	X
american_scientific_journal-766	387	2	66	66	NUM
american_scientific_journal-766	387	3	]	]	PUNCT
american_scientific_journal-766	387	4	murakami	murakami	NOUN
american_scientific_journal-766	387	5	e	e	PROPN
american_scientific_journal-766	387	6	,	,	PUNCT
american_scientific_journal-766	387	7	tolstykh	tolstykh	PROPN
american_scientific_journal-766	387	8	t	t	PROPN
american_scientific_journal-766	387	9	,	,	PUNCT
american_scientific_journal-766	387	10	bao	bao	PROPN
american_scientific_journal-766	387	11	h	h	PROPN
american_scientific_journal-766	387	12	,	,	PUNCT
american_scientific_journal-766	387	13	niu	niu	PROPN
american_scientific_journal-766	387	14	c	c	PROPN
american_scientific_journal-766	387	15	,	,	PUNCT
american_scientific_journal-766	387	16	steuer	steuer	PROPN
american_scientific_journal-766	387	17	hm	hm	PROPN
american_scientific_journal-766	387	18	,	,	PUNCT
american_scientific_journal-766	387	19	bao	bao	PROPN
american_scientific_journal-766	387	20	d	d	PROPN
american_scientific_journal-766	387	21	,	,	PUNCT
american_scientific_journal-766	387	22	et	et	PROPN
american_scientific_journal-766	387	23	al	al	PROPN
american_scientific_journal-766	387	24	.	.	PROPN
american_scientific_journal-766	387	25	,(2010	,(2010	PROPN
american_scientific_journal-766	387	26	)	)	PUNCT
american_scientific_journal-766	387	27	,	,	PUNCT
american_scientific_journal-766	387	28	mechanism	mechanism	NOUN
american_scientific_journal-766	387	29	of	of	ADP
american_scientific_journal-766	387	30	activation	activation	NOUN
american_scientific_journal-766	387	31	of	of	ADP
american_scientific_journal-766	387	32	psi-7851	psi-7851	NOUN
american_scientific_journal-766	387	33	and	and	CCONJ
american_scientific_journal-766	387	34	its	its	PRON
american_scientific_journal-766	387	35	diastereoisomer	diastereoisomer	NOUN
american_scientific_journal-766	387	36	psi-7977	psi-7977	NOUN
american_scientific_journal-766	387	37	,	,	PUNCT
american_scientific_journal-766	387	38	j	j	PROPN
american_scientific_journal-766	387	39	biol	biol	PROPN
american_scientific_journal-766	387	40	chem	chem	NOUN
american_scientific_journal-766	387	41	,	,	PUNCT
american_scientific_journal-766	387	42	285	285	NUM
american_scientific_journal-766	387	43	(	(	PUNCT
american_scientific_journal-766	387	44	45	45	NUM
american_scientific_journal-766	387	45	)	)	PUNCT
american_scientific_journal-766	387	46	,	,	PUNCT
american_scientific_journal-766	387	47	34337–47	34337–47	NUM
american_scientific_journal-766	387	48	.	.	PUNCT
american_scientific_journal-766	388	1	[	[	X
american_scientific_journal-766	388	2	67	67	NUM
american_scientific_journal-766	388	3	]	]	X
american_scientific_journal-766	388	4	chae	chae	PROPN
american_scientific_journal-766	388	5	hb	hb	PROPN
american_scientific_journal-766	388	6	,	,	PUNCT
american_scientific_journal-766	388	7	park	park	NOUN
american_scientific_journal-766	388	8	sm	sm	PROPN
american_scientific_journal-766	388	9	,	,	PUNCT
american_scientific_journal-766	388	10	youn	youn	PROPN
american_scientific_journal-766	388	11	sj(2013	sj(2013	NUM
american_scientific_journal-766	388	12	)	)	PUNCT
american_scientific_journal-766	388	13	,	,	PUNCT
american_scientific_journal-766	388	14	,	,	PUNCT
american_scientific_journal-766	388	15	direct	direct	ADJ
american_scientific_journal-766	388	16	-	-	PUNCT
american_scientific_journal-766	388	17	acting	act	VERB
american_scientific_journal-766	388	18	antivirals	antiviral	NOUN
american_scientific_journal-766	388	19	for	for	ADP
american_scientific_journal-766	388	20	the	the	DET
american_scientific_journal-766	388	21	treatment	treatment	NOUN
american_scientific_journal-766	388	22	of	of	ADP
american_scientific_journal-766	388	23	chronic	chronic	ADJ
american_scientific_journal-766	388	24	hepatitis	hepatitis	NOUN
american_scientific_journal-766	388	25	c	c	NOUN
american_scientific_journal-766	388	26	:	:	PUNCT
american_scientific_journal-766	388	27	open	open	ADJ
american_scientific_journal-766	388	28	issues	issue	NOUN
american_scientific_journal-766	388	29	and	and	CCONJ
american_scientific_journal-766	388	30	future	future	ADJ
american_scientific_journal-766	388	31	perspectives	perspective	NOUN
american_scientific_journal-766	388	32	,	,	PUNCT
american_scientific_journal-766	388	33	scientific	scientific	ADJ
american_scientific_journal-766	388	34	world	world	NOUN
american_scientific_journal-766	388	35	journal	journal	NOUN
american_scientific_journal-766	388	36	,	,	PUNCT
american_scientific_journal-766	388	37	704912	704912	NUM
american_scientific_journal-766	388	38	.	.	PUNCT
american_scientific_journal-766	389	1	[	[	X
american_scientific_journal-766	389	2	68	68	NUM
american_scientific_journal-766	389	3	]	]	X
american_scientific_journal-766	389	4	degasperi	degasperi	PROPN
american_scientific_journal-766	389	5	e	e	PROPN
american_scientific_journal-766	389	6	,	,	PUNCT
american_scientific_journal-766	389	7	aghemo	aghemo	VERB
american_scientific_journal-766	389	8	a	a	DET
american_scientific_journal-766	389	9	,	,	PUNCT
american_scientific_journal-766	389	10	(	(	PUNCT
american_scientific_journal-766	389	11	2014),sofosbuvir	2014),sofosbuvir	NUM
american_scientific_journal-766	389	12	for	for	ADP
american_scientific_journal-766	389	13	the	the	DET
american_scientific_journal-766	389	14	treatment	treatment	NOUN
american_scientific_journal-766	389	15	of	of	ADP
american_scientific_journal-766	389	16	chronic	chronic	ADJ
american_scientific_journal-766	389	17	hepatitis	hepatitis	NOUN
american_scientific_journal-766	389	18	c	c	NOUN
american_scientific_journal-766	389	19	:	:	PUNCT
american_scientific_journal-766	389	20	between	between	ADP
american_scientific_journal-766	389	21	current	current	ADJ
american_scientific_journal-766	389	22	evidence	evidence	NOUN
american_scientific_journal-766	389	23	and	and	CCONJ
american_scientific_journal-766	389	24	future	future	ADJ
american_scientific_journal-766	389	25	perspectives	perspective	NOUN
american_scientific_journal-766	389	26	,	,	PUNCT
american_scientific_journal-766	389	27	hepat	hepat	PROPN
american_scientific_journal-766	389	28	med	med	PROPN
american_scientific_journal-766	389	29	.	.	PROPN
american_scientific_journal-766	390	1	6	6	NUM
american_scientific_journal-766	390	2	,	,	PUNCT
american_scientific_journal-766	390	3	25–33	25–33	NUM
american_scientific_journal-766	390	4	.	.	PUNCT
american_scientific_journal-766	391	1	[	[	X
american_scientific_journal-766	391	2	69	69	NUM
american_scientific_journal-766	391	3	]	]	PUNCT
american_scientific_journal-766	391	4	cholongitas	cholongitas	NOUN
american_scientific_journal-766	391	5	e	e	NOUN
american_scientific_journal-766	391	6	,	,	PUNCT
american_scientific_journal-766	391	7	papatheodoridis	papatheodoridis	PROPN
american_scientific_journal-766	391	8	gv,(2014	gv,(2014	NOUN
american_scientific_journal-766	391	9	)	)	PUNCT
american_scientific_journal-766	391	10	,	,	PUNCT
american_scientific_journal-766	391	11	sofosbuvir	sofosbuvir	VERB
american_scientific_journal-766	391	12	:	:	PUNCT
american_scientific_journal-766	391	13	a	a	DET
american_scientific_journal-766	391	14	novel	novel	ADJ
american_scientific_journal-766	391	15	oral	oral	ADJ
american_scientific_journal-766	391	16	agent	agent	NOUN
american_scientific_journal-766	391	17	for	for	ADP
american_scientific_journal-766	391	18	chronic	chronic	ADJ
american_scientific_journal-766	391	19	hepatitis	hepatitis	NOUN
american_scientific_journal-766	391	20	c	c	NOUN
american_scientific_journal-766	391	21	,	,	PUNCT
american_scientific_journal-766	391	22	ann	ann	PROPN
american_scientific_journal-766	391	23	gastroenterol	gastroenterol	PROPN
american_scientific_journal-766	391	24	,	,	PUNCT
american_scientific_journal-766	391	25	27(4	27(4	PROPN
american_scientific_journal-766	391	26	)	)	PUNCT
american_scientific_journal-766	391	27	,	,	PUNCT
american_scientific_journal-766	391	28	331–337	331–337	NUM
american_scientific_journal-766	391	29	.	.	PUNCT
american_scientific_journal-766	392	1	[	[	X
american_scientific_journal-766	392	2	70	70	NUM
american_scientific_journal-766	392	3	]	]	X
american_scientific_journal-766	392	4	jacobson	jacobson	PROPN
american_scientific_journal-766	392	5	i	i	PROPN
american_scientific_journal-766	392	6	m	m	PROPN
american_scientific_journal-766	392	7	,	,	PUNCT
american_scientific_journal-766	392	8	gordon	gordon	PROPN
american_scientific_journal-766	392	9	sc	sc	PROPN
american_scientific_journal-766	392	10	,	,	PUNCT
american_scientific_journal-766	392	11	kowdley	kowdley	PROPN
american_scientific_journal-766	392	12	kv	kv	PROPN
american_scientific_journal-766	392	13	,	,	PUNCT
american_scientific_journal-766	392	14	kowdley	kowdley	PROPN
american_scientific_journal-766	392	15	kv	kv	PROPN
american_scientific_journal-766	392	16	,	,	PUNCT
american_scientific_journal-766	392	17	yoshida	yoshida	PROPN
american_scientific_journal-766	392	18	em	em	PRON
american_scientific_journal-766	392	19	,	,	PUNCT
american_scientific_journal-766	392	20	et	et	PROPN
american_scientific_journal-766	392	21	al	al	PROPN
american_scientific_journal-766	392	22	.	.	PROPN
american_scientific_journal-766	392	23	,	,	PUNCT
american_scientific_journal-766	392	24	(	(	PUNCT
american_scientific_journal-766	392	25	2013	2013	NUM
american_scientific_journal-766	392	26	)	)	PUNCT
american_scientific_journal-766	392	27	,	,	PUNCT
american_scientific_journal-766	392	28	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	392	29	for	for	ADP
american_scientific_journal-766	392	30	hepatitis	hepatitis	PROPN
american_scientific_journal-766	392	31	c	c	PROPN
american_scientific_journal-766	392	32	genotype	genotype	NOUN
american_scientific_journal-766	392	33	2	2	NUM
american_scientific_journal-766	392	34	or	or	CCONJ
american_scientific_journal-766	392	35	3	3	NUM
american_scientific_journal-766	392	36	in	in	ADP
american_scientific_journal-766	392	37	patients	patient	NOUN
american_scientific_journal-766	392	38	without	without	ADP
american_scientific_journal-766	392	39	treatment	treatment	NOUN
american_scientific_journal-766	392	40	options	option	NOUN
american_scientific_journal-766	392	41	,	,	PUNCT
american_scientific_journal-766	392	42	n	n	CCONJ
american_scientific_journal-766	392	43	engl	engl	PROPN
american_scientific_journal-766	392	44	j	j	PROPN
american_scientific_journal-766	392	45	med	med	PROPN
american_scientific_journal-766	392	46	,	,	PUNCT
american_scientific_journal-766	392	47	368(20),1867–77	368(20),1867–77	NUM
american_scientific_journal-766	392	48	.	.	PUNCT
american_scientific_journal-766	393	1	[	[	X
american_scientific_journal-766	393	2	71	71	NUM
american_scientific_journal-766	393	3	]	]	X
american_scientific_journal-766	393	4	kirby	kirby	PROPN
american_scientific_journal-766	393	5	b	b	PROPN
american_scientific_journal-766	393	6	,	,	PUNCT
american_scientific_journal-766	393	7	gordi	gordi	PROPN
american_scientific_journal-766	393	8	t	t	PROPN
american_scientific_journal-766	393	9	,	,	PUNCT
american_scientific_journal-766	393	10	symonds	symonds	PROPN
american_scientific_journal-766	393	11	wt	wt	PROPN
american_scientific_journal-766	393	12	,	,	PUNCT
american_scientific_journal-766	393	13	kearney	kearney	PROPN
american_scientific_journal-766	393	14	bp	bp	PROPN
american_scientific_journal-766	393	15	,	,	PUNCT
american_scientific_journal-766	393	16	mathias	mathias	PROPN
american_scientific_journal-766	393	17	a,(2013	a,(2013	PROPN
american_scientific_journal-766	393	18	)	)	PUNCT
american_scientific_journal-766	393	19	,	,	PUNCT
american_scientific_journal-766	393	20	population	population	NOUN
american_scientific_journal-766	393	21	pharmacokinetics	pharmacokinetic	NOUN
american_scientific_journal-766	393	22	of	of	ADP
american_scientific_journal-766	393	23	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	393	24	and	and	CCONJ
american_scientific_journal-766	393	25	its	its	PRON
american_scientific_journal-766	393	26	major	major	ADJ
american_scientific_journal-766	393	27	metabolite	metabolite	NOUN
american_scientific_journal-766	393	28	(	(	PUNCT
american_scientific_journal-766	393	29	gs-331007	gs-331007	ADJ
american_scientific_journal-766	393	30	)	)	PUNCT
american_scientific_journal-766	393	31	in	in	ADP
american_scientific_journal-766	393	32	healthy	healthy	ADJ
american_scientific_journal-766	393	33	and	and	CCONJ
american_scientific_journal-766	393	34	hcv	hcv	NOUN
american_scientific_journal-766	393	35	-	-	PUNCT
american_scientific_journal-766	393	36	infected	infect	VERB
american_scientific_journal-766	393	37	adult	adult	NOUN
american_scientific_journal-766	393	38	subjects	subject	NOUN
american_scientific_journal-766	393	39	;	;	PUNCT
american_scientific_journal-766	393	40	64th	64th	ADJ
american_scientific_journal-766	393	41	annual	annual	ADJ
american_scientific_journal-766	393	42	meeting	meeting	NOUN
american_scientific_journal-766	393	43	of	of	ADP
american_scientific_journal-766	393	44	the	the	DET
american_scientific_journal-766	393	45	american	american	PROPN
american_scientific_journal-766	393	46	association	association	PROPN
american_scientific_journal-766	393	47	for	for	ADP
american_scientific_journal-766	393	48	the	the	DET
american_scientific_journal-766	393	49	study	study	NOUN
american_scientific_journal-766	393	50	of	of	ADP
american_scientific_journal-766	393	51	liver	liver	NOUN
american_scientific_journal-766	393	52	diseases	disease	NOUN
american_scientific_journal-766	393	53	,	,	PUNCT
american_scientific_journal-766	393	54	november	november	PROPN
american_scientific_journal-766	393	55	1–5	1–5	NUM
american_scientific_journal-766	393	56	,	,	PUNCT
american_scientific_journal-766	393	57	washington	washington	PROPN
american_scientific_journal-766	393	58	,	,	PUNCT
american_scientific_journal-766	393	59	dc	dc	PROPN
american_scientific_journal-766	393	60	.	.	PUNCT
american_scientific_journal-766	394	1	[	[	X
american_scientific_journal-766	394	2	72	72	NUM
american_scientific_journal-766	394	3	]	]	PUNCT
american_scientific_journal-766	394	4	elbaza	elbaza	PROPN
american_scientific_journal-766	394	5	t	t	PROPN
american_scientific_journal-766	394	6	,	,	PUNCT
american_scientific_journal-766	394	7	el	el	PROPN
american_scientific_journal-766	394	8	-	-	PUNCT
american_scientific_journal-766	394	9	kassasb	kassasb	PROPN
american_scientific_journal-766	394	10	m	m	PROPN
american_scientific_journal-766	394	11	,	,	PUNCT
american_scientific_journal-766	394	12	esmata	esmata	PROPN
american_scientific_journal-766	394	13	g,(2014	g,(2014	PROPN
american_scientific_journal-766	394	14	)	)	PUNCT
american_scientific_journal-766	394	15	,	,	PUNCT
american_scientific_journal-766	394	16	new	new	ADJ
american_scientific_journal-766	394	17	era	era	NOUN
american_scientific_journal-766	394	18	for	for	ADP
american_scientific_journal-766	394	19	management	management	NOUN
american_scientific_journal-766	394	20	of	of	ADP
american_scientific_journal-766	394	21	chronic	chronic	ADJ
american_scientific_journal-766	394	22	hepatitis	hepatitis	PROPN
american_scientific_journal-766	394	23	c	c	PROPN
american_scientific_journal-766	394	24	virus	virus	PROPN
american_scientific_journal-766	394	25	21	21	NUM
american_scientific_journal-766	394	26	http://doctorsoftheworld.org/wp-content/uploads/2013/07/gileads-hcv-drug-sofosbuvir-approved-but-accessible-for-how-many-09dec2013.pdf	http://doctorsoftheworld.org/wp-content/uploads/2013/07/gileads-hcv-drug-sofosbuvir-approved-but-accessible-for-how-many-09dec2013.pdf	PROPN
american_scientific_journal-766	394	27	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4068585	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4068585	NOUN
american_scientific_journal-766	394	28	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4068585	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4068585	NOUN
american_scientific_journal-766	394	29	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4068585	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc4068585	NOUN
american_scientific_journal-766	394	30	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc2966047	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc2966047	NOUN
american_scientific_journal-766	394	31	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc2966047	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc2966047	PROPN
american_scientific_journal-766	394	32	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3687480	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3687480	PROPN
american_scientific_journal-766	394	33	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3687480	http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3687480	NOUN
american_scientific_journal-766	394	34	http://www.ncbi.nlm.nih.gov/pubmed/?term=degasperi%20e%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=degasperi%20e%5bauth%5d	NOUN
american_scientific_journal-766	395	1	http://www.ncbi.nlm.nih.gov/pubmed/?term=aghemo%20a%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=aghemo%20a%5bauth%5d	PROPN
american_scientific_journal-766	395	2	http://www.ncbi.nlm.nih.gov/pubmed/?term=cholongitas%20e%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=cholongitas%20e%5bauth%5d	PROPN
american_scientific_journal-766	395	3	http://www.ncbi.nlm.nih.gov/pubmed/?term=papatheodoridis%20gv%5bauth%5d	http://www.ncbi.nlm.nih.gov/pubmed/?term=papatheodoridis%20gv%5bauth%5d	ADP
american_scientific_journal-766	395	4	american	american	PROPN
american_scientific_journal-766	395	5	scientific	scientific	PROPN
american_scientific_journal-766	395	6	research	research	PROPN
american_scientific_journal-766	395	7	journal	journal	NOUN
american_scientific_journal-766	395	8	for	for	ADP
american_scientific_journal-766	395	9	engineering	engineering	NOUN
american_scientific_journal-766	395	10	,	,	PUNCT
american_scientific_journal-766	395	11	technology	technology	NOUN
american_scientific_journal-766	395	12	,	,	PUNCT
american_scientific_journal-766	395	13	and	and	CCONJ
american_scientific_journal-766	395	14	sciences	science	NOUN
american_scientific_journal-766	395	15	(	(	PUNCT
american_scientific_journal-766	395	16	asrjets	asrjet	NOUN
american_scientific_journal-766	395	17	)	)	PUNCT
american_scientific_journal-766	395	18	(	(	PUNCT
american_scientific_journal-766	395	19	2015	2015	NUM
american_scientific_journal-766	395	20	)	)	PUNCT
american_scientific_journal-766	395	21	volume	volume	NOUN
american_scientific_journal-766	395	22	13	13	NUM
american_scientific_journal-766	395	23	,	,	PUNCT
american_scientific_journal-766	395	24	no	no	DET
american_scientific_journal-766	395	25	1	1	NUM
american_scientific_journal-766	395	26	,	,	PUNCT
american_scientific_journal-766	395	27	pp	pp	ADV
american_scientific_journal-766	395	28	1	1	NUM
american_scientific_journal-766	395	29	-	-	SYM
american_scientific_journal-766	395	30	23	23	NUM
american_scientific_journal-766	395	31	using	use	VERB
american_scientific_journal-766	395	32	direct	direct	ADJ
american_scientific_journal-766	395	33	antiviral	antiviral	ADJ
american_scientific_journal-766	395	34	agents	agent	NOUN
american_scientific_journal-766	395	35	:	:	PUNCT
american_scientific_journal-766	395	36	a	a	DET
american_scientific_journal-766	395	37	review	review	NOUN
american_scientific_journal-766	395	38	.	.	PUNCT
american_scientific_journal-766	396	1	j	j	PROPN
american_scientific_journal-766	396	2	adv	adv	PROPN
american_scientific_journal-766	396	3	res	re	NOUN
american_scientific_journal-766	396	4	,	,	PUNCT
american_scientific_journal-766	396	5	doi:10.1016	doi:10.1016	PROPN
american_scientific_journal-766	396	6	/	/	SYM
american_scientific_journal-766	396	7	j.jare.2014.11.004	j.jare.2014.11.004	PROPN
american_scientific_journal-766	397	1	[	[	X
american_scientific_journal-766	397	2	73	73	NUM
american_scientific_journal-766	397	3	]	]	X
american_scientific_journal-766	397	4	lawitz	lawitz	PROPN
american_scientific_journal-766	397	5	e	e	NOUN
american_scientific_journal-766	397	6	,	,	PUNCT
american_scientific_journal-766	397	7	lalezari	lalezari	PROPN
american_scientific_journal-766	397	8	j	j	PROPN
american_scientific_journal-766	397	9	,	,	PUNCT
american_scientific_journal-766	397	10	hassanein	hassanein	PROPN
american_scientific_journal-766	397	11	t	t	PROPN
american_scientific_journal-766	397	12	,	,	PUNCT
american_scientific_journal-766	397	13	kowdley	kowdley	PROPN
american_scientific_journal-766	397	14	k	k	PROPN
american_scientific_journal-766	397	15	,	,	PUNCT
american_scientific_journal-766	397	16	poordad	poordad	NOUN
american_scientific_journal-766	397	17	f	f	X
american_scientific_journal-766	397	18	,	,	PUNCT
american_scientific_journal-766	397	19	sheikh	sheikh	PROPN
american_scientific_journal-766	397	20	a	a	PRON
american_scientific_journal-766	397	21	,	,	PUNCT
american_scientific_journal-766	397	22	et	et	PROPN
american_scientific_journal-766	397	23	al	al	PROPN
american_scientific_journal-766	397	24	.	.	PROPN
american_scientific_journal-766	397	25	,	,	PUNCT
american_scientific_journal-766	397	26	(	(	PUNCT
american_scientific_journal-766	397	27	2013),sofosbuvir	2013),sofosbuvir	NUM
american_scientific_journal-766	397	28	in	in	ADP
american_scientific_journal-766	397	29	combination	combination	NOUN
american_scientific_journal-766	397	30	with	with	ADP
american_scientific_journal-766	397	31	peginterferon	peginterferon	NOUN
american_scientific_journal-766	397	32	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	397	33	and	and	CCONJ
american_scientific_journal-766	397	34	ribavirin	ribavirin	NOUN
american_scientific_journal-766	397	35	for	for	ADP
american_scientific_journal-766	397	36	non	non	ADJ
american_scientific_journal-766	397	37	-	-	ADJ
american_scientific_journal-766	397	38	cirrhotic	cirrhotic	ADJ
american_scientific_journal-766	397	39	,	,	PUNCT
american_scientific_journal-766	397	40	treatment	treatment	NOUN
american_scientific_journal-766	397	41	-	-	PUNCT
american_scientific_journal-766	397	42	naive	naive	ADJ
american_scientific_journal-766	397	43	patients	patient	NOUN
american_scientific_journal-766	397	44	with	with	ADP
american_scientific_journal-766	397	45	genotypes	genotype	NOUN
american_scientific_journal-766	397	46	1	1	NUM
american_scientific_journal-766	397	47	,	,	PUNCT
american_scientific_journal-766	397	48	2	2	NUM
american_scientific_journal-766	397	49	,	,	PUNCT
american_scientific_journal-766	397	50	and	and	CCONJ
american_scientific_journal-766	397	51	3	3	NUM
american_scientific_journal-766	397	52	hepatitis	hepatitis	NOUN
american_scientific_journal-766	397	53	c	c	NOUN
american_scientific_journal-766	397	54	infection	infection	NOUN
american_scientific_journal-766	397	55	:	:	PUNCT
american_scientific_journal-766	397	56	a	a	DET
american_scientific_journal-766	397	57	randomized	randomized	ADJ
american_scientific_journal-766	397	58	,	,	PUNCT
american_scientific_journal-766	397	59	double	double	ADJ
american_scientific_journal-766	397	60	-	-	PUNCT
american_scientific_journal-766	397	61	blind	blind	ADJ
american_scientific_journal-766	397	62	,	,	PUNCT
american_scientific_journal-766	397	63	phase	phase	NOUN
american_scientific_journal-766	397	64	2	2	NUM
american_scientific_journal-766	397	65	trial	trial	NOUN
american_scientific_journal-766	397	66	,	,	PUNCT
american_scientific_journal-766	397	67	lancet	lancet	NOUN
american_scientific_journal-766	397	68	infect	infect	NOUN
american_scientific_journal-766	397	69	,	,	PUNCT
american_scientific_journal-766	397	70	13	13	NUM
american_scientific_journal-766	397	71	,	,	PUNCT
american_scientific_journal-766	397	72	401–408	401–408	NUM
american_scientific_journal-766	397	73	[	[	X
american_scientific_journal-766	397	74	74	74	NUM
american_scientific_journal-766	397	75	]	]	PUNCT
american_scientific_journal-766	397	76	kowdley	kowdley	PROPN
american_scientific_journal-766	397	77	k	k	PROPN
american_scientific_journal-766	397	78	,	,	PUNCT
american_scientific_journal-766	397	79	lawitz	lawitz	PROPN
american_scientific_journal-766	397	80	e	e	PROPN
american_scientific_journal-766	397	81	,	,	PUNCT
american_scientific_journal-766	397	82	crespo	crespo	PROPN
american_scientific_journal-766	397	83	i	i	PRON
american_scientific_journal-766	397	84	,	,	PUNCT
american_scientific_journal-766	397	85	hassanein	hassanein	PROPN
american_scientific_journal-766	397	86	t	t	PROPN
american_scientific_journal-766	397	87	,	,	PUNCT
american_scientific_journal-766	397	88	davis	davis	PROPN
american_scientific_journal-766	397	89	m	m	PROPN
american_scientific_journal-766	397	90	,	,	PUNCT
american_scientific_journal-766	397	91	demicco	demicco	PROPN
american_scientific_journal-766	397	92	m	m	PROPN
american_scientific_journal-766	397	93	,	,	PUNCT
american_scientific_journal-766	397	94	et	et	PROPN
american_scientific_journal-766	397	95	al	al	PROPN
american_scientific_journal-766	397	96	.	.	PROPN
american_scientific_journal-766	397	97	,	,	PUNCT
american_scientific_journal-766	397	98	(	(	PUNCT
american_scientific_journal-766	397	99	2013),sofosbuvir	2013),sofosbuvir	NUM
american_scientific_journal-766	397	100	with	with	ADP
american_scientific_journal-766	397	101	pegylated	pegylated	ADJ
american_scientific_journal-766	397	102	interferon	interferon	NOUN
american_scientific_journal-766	397	103	alfa-2a	alfa-2a	PUNCT
american_scientific_journal-766	397	104	and	and	CCONJ
american_scientific_journal-766	397	105	ribavirin	ribavirin	NOUN
american_scientific_journal-766	397	106	for	for	ADP
american_scientific_journal-766	397	107	treatment	treatment	NOUN
american_scientific_journal-766	397	108	-	-	PUNCT
american_scientific_journal-766	397	109	naive	naive	ADJ
american_scientific_journal-766	397	110	patients	patient	NOUN
american_scientific_journal-766	397	111	with	with	ADP
american_scientific_journal-766	397	112	hepatitis	hepatitis	PROPN
american_scientific_journal-766	397	113	c	c	PROPN
american_scientific_journal-766	397	114	genotype-1	genotype-1	PROPN
american_scientific_journal-766	397	115	infection	infection	NOUN
american_scientific_journal-766	397	116	(	(	PUNCT
american_scientific_journal-766	397	117	atomic	atomic	NOUN
american_scientific_journal-766	397	118	):	):	PUNCT
american_scientific_journal-766	397	119	an	an	DET
american_scientific_journal-766	397	120	open	open	ADJ
american_scientific_journal-766	397	121	-	-	PUNCT
american_scientific_journal-766	397	122	label	label	NOUN
american_scientific_journal-766	397	123	,	,	PUNCT
american_scientific_journal-766	397	124	randomised	randomise	VERB
american_scientific_journal-766	397	125	,	,	PUNCT
american_scientific_journal-766	397	126	multicentre	multicentre	NOUN
american_scientific_journal-766	397	127	phase	phase	NOUN
american_scientific_journal-766	397	128	2	2	NUM
american_scientific_journal-766	397	129	trial	trial	NOUN
american_scientific_journal-766	397	130	,	,	PUNCT
american_scientific_journal-766	397	131	lancet	lancet	NOUN
american_scientific_journal-766	397	132	,	,	PUNCT
american_scientific_journal-766	397	133	381	381	NUM
american_scientific_journal-766	397	134	,	,	PUNCT
american_scientific_journal-766	397	135	2100–07	2100–07	NUM
american_scientific_journal-766	398	1	[	[	X
american_scientific_journal-766	398	2	75	75	NUM
american_scientific_journal-766	398	3	]	]	X
american_scientific_journal-766	398	4	gane	gane	NOUN
american_scientific_journal-766	398	5	e	e	PROPN
american_scientific_journal-766	398	6	,	,	PUNCT
american_scientific_journal-766	398	7	stedman	stedman	PROPN
american_scientific_journal-766	398	8	c	c	PROPN
american_scientific_journal-766	398	9	,	,	PUNCT
american_scientific_journal-766	398	10	hyland	hyland	PROPN
american_scientific_journal-766	398	11	r	r	PROPN
american_scientific_journal-766	398	12	,	,	PUNCT
american_scientific_journal-766	398	13	pang	pang	NOUN
american_scientific_journal-766	398	14	p	p	NOUN
american_scientific_journal-766	398	15	,	,	PUNCT
american_scientific_journal-766	398	16	ding	ding	NOUN
american_scientific_journal-766	398	17	x	x	SYM
american_scientific_journal-766	398	18	,	,	PUNCT
american_scientific_journal-766	398	19	symonds	symonds	PROPN
american_scientific_journal-766	398	20	w	w	PROPN
american_scientific_journal-766	398	21	,	,	PUNCT
american_scientific_journal-766	398	22	et	et	PROPN
american_scientific_journal-766	398	23	al	al	PROPN
american_scientific_journal-766	398	24	.	.	PROPN
american_scientific_journal-766	398	25	,(2013	,(2013	PROPN
american_scientific_journal-766	398	26	)	)	PUNCT
american_scientific_journal-766	398	27	,	,	PUNCT
american_scientific_journal-766	398	28	all	all	PRON
american_scientific_journal-766	398	29	-	-	PUNCT
american_scientific_journal-766	398	30	oral	oral	ADJ
american_scientific_journal-766	398	31	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	398	32	-	-	PUNCT
american_scientific_journal-766	398	33	based	base	VERB
american_scientific_journal-766	398	34	12	12	NUM
american_scientific_journal-766	398	35	-	-	PUNCT
american_scientific_journal-766	398	36	week	week	NOUN
american_scientific_journal-766	398	37	regimens	regimen	NOUN
american_scientific_journal-766	398	38	for	for	ADP
american_scientific_journal-766	398	39	the	the	DET
american_scientific_journal-766	398	40	treatment	treatment	NOUN
american_scientific_journal-766	398	41	of	of	ADP
american_scientific_journal-766	398	42	chronic	chronic	ADJ
american_scientific_journal-766	398	43	hcv	hcv	NOUN
american_scientific_journal-766	398	44	infection	infection	NOUN
american_scientific_journal-766	398	45	:	:	PUNCT
american_scientific_journal-766	398	46	the	the	DET
american_scientific_journal-766	398	47	electron	electron	NOUN
american_scientific_journal-766	398	48	study	study	NOUN
american_scientific_journal-766	398	49	,	,	PUNCT
american_scientific_journal-766	398	50	j	j	PROPN
american_scientific_journal-766	398	51	hepatol	hepatol	ADJ
american_scientific_journal-766	398	52	,	,	PUNCT
american_scientific_journal-766	398	53	58(s1	58(s1	NUM
american_scientific_journal-766	398	54	–	–	PUNCT
american_scientific_journal-766	398	55	s24	s24	NOUN
american_scientific_journal-766	398	56	)	)	PUNCT
american_scientific_journal-766	398	57	,	,	PUNCT
american_scientific_journal-766	398	58	a14	a14	PROPN
american_scientific_journal-766	399	1	[	[	X
american_scientific_journal-766	399	2	76	76	NUM
american_scientific_journal-766	399	3	]	]	X
american_scientific_journal-766	399	4	lalezari	lalezari	ADJ
american_scientific_journal-766	399	5	jp	jp	PROPN
american_scientific_journal-766	399	6	,	,	PUNCT
american_scientific_journal-766	399	7	nelson	nelson	PROPN
american_scientific_journal-766	399	8	dr	dr	PROPN
american_scientific_journal-766	399	9	,	,	PUNCT
american_scientific_journal-766	399	10	hyland	hyland	PROPN
american_scientific_journal-766	399	11	rh	rh	PROPN
american_scientific_journal-766	399	12	,	,	PUNCT
american_scientific_journal-766	399	13	lin	lin	PROPN
american_scientific_journal-766	399	14	m	m	PROPN
american_scientific_journal-766	399	15	,	,	PUNCT
american_scientific_journal-766	399	16	rossi	rossi	PROPN
american_scientific_journal-766	399	17	sj	sj	PROPN
american_scientific_journal-766	399	18	,	,	PUNCT
american_scientific_journal-766	399	19	symonds	symonds	PROPN
american_scientific_journal-766	399	20	wt	wt	PROPN
american_scientific_journal-766	399	21	,	,	PUNCT
american_scientific_journal-766	399	22	et	et	PROPN
american_scientific_journal-766	399	23	al	al	PROPN
american_scientific_journal-766	399	24	.	.	PROPN
american_scientific_journal-766	399	25	,(2013	,(2013	PROPN
american_scientific_journal-766	399	26	)	)	PUNCT
american_scientific_journal-766	399	27	,	,	PUNCT
american_scientific_journal-766	399	28	once	once	ADV
american_scientific_journal-766	399	29	daily	daily	ADV
american_scientific_journal-766	399	30	sofosbuvir	sofosbuvir	NOUN
american_scientific_journal-766	399	31	plus	plus	CCONJ
american_scientific_journal-766	399	32	ribavirin	ribavirin	NOUN
american_scientific_journal-766	399	33	for	for	ADP
american_scientific_journal-766	399	34	12	12	NUM
american_scientific_journal-766	399	35	and	and	CCONJ
american_scientific_journal-766	399	36	24	24	NUM
american_scientific_journal-766	399	37	weeks	week	NOUN
american_scientific_journal-766	399	38	in	in	ADP
american_scientific_journal-766	399	39	treatment	treatment	NOUN
american_scientific_journal-766	399	40	-	-	PUNCT
american_scientific_journal-766	399	41	naïve	naïve	ADJ
american_scientific_journal-766	399	42	patients	patient	NOUN
american_scientific_journal-766	399	43	with	with	ADP
american_scientific_journal-766	399	44	hcv	hcv	NOUN
american_scientific_journal-766	399	45	infection	infection	NOUN
american_scientific_journal-766	399	46	:	:	PUNCT
american_scientific_journal-766	399	47	the	the	DET
american_scientific_journal-766	399	48	quantum	quantum	NOUN
american_scientific_journal-766	399	49	study	study	NOUN
american_scientific_journal-766	399	50	,	,	PUNCT
american_scientific_journal-766	399	51	j	j	PROPN
american_scientific_journal-766	399	52	hepatol	hepatol	ADJ
american_scientific_journal-766	399	53	,	,	PUNCT
american_scientific_journal-766	399	54	58	58	NUM
american_scientific_journal-766	399	55	,	,	PUNCT
american_scientific_journal-766	399	56	s236	s236	PROPN
american_scientific_journal-766	400	1	[	[	X
american_scientific_journal-766	400	2	77	77	NUM
american_scientific_journal-766	400	3	]	]	X
american_scientific_journal-766	400	4	lawitz	lawitz	PROPN
american_scientific_journal-766	400	5	e	e	PROPN
american_scientific_journal-766	400	6	,	,	PUNCT
american_scientific_journal-766	400	7	mangia	mangia	PROPN
american_scientific_journal-766	400	8	a	a	PRON
american_scientific_journal-766	400	9	,	,	PUNCT
american_scientific_journal-766	400	10	wyles	wyles	PROPN
american_scientific_journal-766	400	11	d	d	PROPN
american_scientific_journal-766	400	12	,	,	PUNCT
american_scientific_journal-766	400	13	rodriguez	rodriguez	NOUN
american_scientific_journal-766	400	14	-	-	PUNCT
american_scientific_journal-766	400	15	torres	torres	PROPN
american_scientific_journal-766	400	16	m	m	PROPN
american_scientific_journal-766	400	17	,	,	PUNCT
american_scientific_journal-766	400	18	hassanein	hassanein	PROPN
american_scientific_journal-766	400	19	t	t	PROPN
american_scientific_journal-766	400	20	,	,	PUNCT
american_scientific_journal-766	400	21	et	et	PROPN
american_scientific_journal-766	400	22	al	al	PROPN
american_scientific_journal-766	400	23	,	,	PUNCT
american_scientific_journal-766	400	24	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	400	25	for	for	ADP
american_scientific_journal-766	400	26	previously	previously	ADV
american_scientific_journal-766	400	27	untreated	untreated	ADJ
american_scientific_journal-766	400	28	chronic	chronic	ADJ
american_scientific_journal-766	400	29	hepatitis	hepatitis	NOUN
american_scientific_journal-766	400	30	c	c	NOUN
american_scientific_journal-766	400	31	infection	infection	NOUN
american_scientific_journal-766	400	32	,	,	PUNCT
american_scientific_journal-766	400	33	n	n	PROPN
american_scientific_journal-766	400	34	engl	engl	PROPN
american_scientific_journal-766	400	35	j	j	PROPN
american_scientific_journal-766	400	36	med	med	PROPN
american_scientific_journal-766	400	37	.	.	PUNCT
american_scientific_journal-766	400	38	2013	2013	NUM
american_scientific_journal-766	400	39	,	,	PUNCT
american_scientific_journal-766	400	40	368,1878–87	368,1878–87	NUM
american_scientific_journal-766	400	41	.	.	PUNCT
american_scientific_journal-766	401	1	[	[	X
american_scientific_journal-766	401	2	78	78	NUM
american_scientific_journal-766	401	3	]	]	X
american_scientific_journal-766	401	4	zeuzem	zeuzem	NOUN
american_scientific_journal-766	401	5	s	s	PROPN
american_scientific_journal-766	401	6	,	,	PUNCT
american_scientific_journal-766	401	7	dusheiko	dusheiko	NOUN
american_scientific_journal-766	401	8	g	g	NOUN
american_scientific_journal-766	401	9	,	,	PUNCT
american_scientific_journal-766	401	10	salupere	salupere	ADJ
american_scientific_journal-766	401	11	r	r	NOUN
american_scientific_journal-766	401	12	,	,	PUNCT
american_scientific_journal-766	401	13	mangia	mangia	ADJ
american_scientific_journal-766	401	14	a	a	PRON
american_scientific_journal-766	401	15	,	,	PUNCT
american_scientific_journal-766	401	16	flisiak	flisiak	PROPN
american_scientific_journal-766	401	17	r	r	PROPN
american_scientific_journal-766	401	18	,	,	PUNCT
american_scientific_journal-766	401	19	et	et	PROPN
american_scientific_journal-766	401	20	al	al	PROPN
american_scientific_journal-766	401	21	.	.	PROPN
american_scientific_journal-766	401	22	,(2013	,(2013	PROPN
american_scientific_journal-766	401	23	)	)	PUNCT
american_scientific_journal-766	401	24	,	,	PUNCT
american_scientific_journal-766	401	25	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	401	26	plus	plus	CCONJ
american_scientific_journal-766	401	27	ribavirin	ribavirin	NOUN
american_scientific_journal-766	401	28	for	for	ADP
american_scientific_journal-766	401	29	12	12	NUM
american_scientific_journal-766	401	30	or	or	CCONJ
american_scientific_journal-766	401	31	24	24	NUM
american_scientific_journal-766	401	32	weeks	week	NOUN
american_scientific_journal-766	401	33	for	for	ADP
american_scientific_journal-766	401	34	patients	patient	NOUN
american_scientific_journal-766	401	35	with	with	ADP
american_scientific_journal-766	401	36	hcv	hcv	NOUN
american_scientific_journal-766	401	37	genotype	genotype	NOUN
american_scientific_journal-766	401	38	2	2	NUM
american_scientific_journal-766	401	39	or	or	CCONJ
american_scientific_journal-766	401	40	3	3	NUM
american_scientific_journal-766	401	41	:	:	PUNCT
american_scientific_journal-766	401	42	the	the	DET
american_scientific_journal-766	401	43	valence	valence	NOUN
american_scientific_journal-766	401	44	trial	trial	NOUN
american_scientific_journal-766	401	45	,	,	PUNCT
american_scientific_journal-766	401	46	hepatology	hepatology	NOUN
american_scientific_journal-766	401	47	,	,	PUNCT
american_scientific_journal-766	401	48	58(4	58(4	NUM
american_scientific_journal-766	401	49	)	)	PUNCT
american_scientific_journal-766	401	50	,	,	PUNCT
american_scientific_journal-766	401	51	733a	733a	NOUN
american_scientific_journal-766	401	52	.	.	PUNCT
american_scientific_journal-766	402	1	[	[	X
american_scientific_journal-766	402	2	79	79	NUM
american_scientific_journal-766	402	3	]	]	X
american_scientific_journal-766	402	4	lawitz	lawitz	PROPN
american_scientific_journal-766	402	5	e	e	NOUN
american_scientific_journal-766	402	6	,	,	PUNCT
american_scientific_journal-766	402	7	poordad	poordad	NOUN
american_scientific_journal-766	402	8	ff	ff	NOUN
american_scientific_journal-766	402	9	,	,	PUNCT
american_scientific_journal-766	402	10	pang	pang	NOUN
american_scientific_journal-766	402	11	ps	ps	PROPN
american_scientific_journal-766	402	12	,	,	PUNCT
american_scientific_journal-766	402	13	hyland	hyland	PROPN
american_scientific_journal-766	402	14	rh	rh	PROPN
american_scientific_journal-766	402	15	,	,	PUNCT
american_scientific_journal-766	402	16	ding	ding	NOUN
american_scientific_journal-766	402	17	x	x	SYM
american_scientific_journal-766	402	18	,	,	PUNCT
american_scientific_journal-766	402	19	mo	mo	PROPN
american_scientific_journal-766	402	20	h	h	PROPN
american_scientific_journal-766	402	21	,	,	PUNCT
american_scientific_journal-766	402	22	et	et	PROPN
american_scientific_journal-766	402	23	al	al	PROPN
american_scientific_journal-766	402	24	.	.	PROPN
american_scientific_journal-766	402	25	,(2014),sofosbuvir	,(2014),sofosbuvir	PUNCT
american_scientific_journal-766	402	26	and	and	CCONJ
american_scientific_journal-766	402	27	ledipasvir	ledipasvir	NOUN
american_scientific_journal-766	402	28	fixed	fix	VERB
american_scientific_journal-766	402	29	-	-	PUNCT
american_scientific_journal-766	402	30	dose	dose	NOUN
american_scientific_journal-766	402	31	combination	combination	NOUN
american_scientific_journal-766	402	32	with	with	ADP
american_scientific_journal-766	402	33	and	and	CCONJ
american_scientific_journal-766	402	34	without	without	ADP
american_scientific_journal-766	402	35	ribavirin	ribavirin	NOUN
american_scientific_journal-766	402	36	in	in	ADP
american_scientific_journal-766	402	37	treatment	treatment	NOUN
american_scientific_journal-766	402	38	-	-	PUNCT
american_scientific_journal-766	402	39	naive	naive	ADJ
american_scientific_journal-766	402	40	and	and	CCONJ
american_scientific_journal-766	402	41	previously	previously	ADV
american_scientific_journal-766	402	42	treated	treat	VERB
american_scientific_journal-766	402	43	patients	patient	NOUN
american_scientific_journal-766	402	44	with	with	ADP
american_scientific_journal-766	402	45	genotype	genotype	NOUN
american_scientific_journal-766	402	46	1	1	NUM
american_scientific_journal-766	402	47	hepatitis	hepatitis	NOUN
american_scientific_journal-766	402	48	c	c	PROPN
american_scientific_journal-766	402	49	virus	virus	NOUN
american_scientific_journal-766	402	50	infection	infection	NOUN
american_scientific_journal-766	402	51	(	(	PUNCT
american_scientific_journal-766	402	52	lonestar):an	lonestar):an	ADV
american_scientific_journal-766	402	53	open	open	ADJ
american_scientific_journal-766	402	54	-	-	PUNCT
american_scientific_journal-766	402	55	label	label	NOUN
american_scientific_journal-766	402	56	,	,	PUNCT
american_scientific_journal-766	402	57	randomised	randomise	VERB
american_scientific_journal-766	402	58	,	,	PUNCT
american_scientific_journal-766	402	59	phase	phase	NOUN
american_scientific_journal-766	402	60	2	2	NUM
american_scientific_journal-766	402	61	trial	trial	NOUN
american_scientific_journal-766	402	62	,	,	PUNCT
american_scientific_journal-766	402	63	lancet	lancet	PROPN
american_scientific_journal-766	402	64	,	,	PUNCT
american_scientific_journal-766	402	65	383,515–23	383,515–23	PROPN
american_scientific_journal-766	402	66	.	.	PUNCT
american_scientific_journal-766	403	1	[	[	X
american_scientific_journal-766	403	2	80	80	NUM
american_scientific_journal-766	403	3	]	]	X
american_scientific_journal-766	403	4	lawitz	lawitz	NOUN
american_scientific_journal-766	403	5	e	e	NOUN
american_scientific_journal-766	403	6	,	,	PUNCT
american_scientific_journal-766	403	7	poordad	poordad	NOUN
american_scientific_journal-766	403	8	f	f	NOUN
american_scientific_journal-766	403	9	,	,	PUNCT
american_scientific_journal-766	403	10	brainanrd	brainanrd	NOUN
american_scientific_journal-766	403	11	d	d	PROPN
american_scientific_journal-766	403	12	,	,	PUNCT
american_scientific_journal-766	403	13	brainard	brainard	PROPN
american_scientific_journal-766	403	14	dm	dm	PROPN
american_scientific_journal-766	403	15	,	,	PUNCT
american_scientific_journal-766	403	16	robert	robert	PROPN
american_scientific_journal-766	403	17	h	h	PROPN
american_scientific_journal-766	403	18	,	,	PUNCT
american_scientific_journal-766	403	19	et	et	NOUN
american_scientific_journal-766	403	20	al,(2013	al,(2013	PROPN
american_scientific_journal-766	403	21	)	)	PUNCT
american_scientific_journal-766	403	22	,	,	PUNCT
american_scientific_journal-766	403	23	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	403	24	in	in	ADP
american_scientific_journal-766	403	25	combination	combination	NOUN
american_scientific_journal-766	403	26	with	with	ADP
american_scientific_journal-766	403	27	peg	peg	NOUN
american_scientific_journal-766	403	28	-	-	PUNCT
american_scientific_journal-766	403	29	ifn	ifn	PROPN
american_scientific_journal-766	403	30	and	and	CCONJ
american_scientific_journal-766	403	31	ribavirin	ribavirin	NOUN
american_scientific_journal-766	403	32	for	for	ADP
american_scientific_journal-766	403	33	12	12	NUM
american_scientific_journal-766	403	34	weeks	week	NOUN
american_scientific_journal-766	403	35	provides	provide	VERB
american_scientific_journal-766	403	36	high	high	ADJ
american_scientific_journal-766	403	37	svr	svr	NOUN
american_scientific_journal-766	403	38	rates	rate	NOUN
american_scientific_journal-766	403	39	in	in	ADP
american_scientific_journal-766	403	40	hcv	hcv	NOUN
american_scientific_journal-766	403	41	-	-	PUNCT
american_scientific_journal-766	403	42	infected	infect	VERB
american_scientific_journal-766	403	43	genotype	genotype	NOUN
american_scientific_journal-766	403	44	2	2	NUM
american_scientific_journal-766	403	45	or	or	CCONJ
american_scientific_journal-766	403	46	3	3	NUM
american_scientific_journal-766	403	47	treatment	treatment	NOUN
american_scientific_journal-766	403	48	experienced	experience	VERB
american_scientific_journal-766	403	49	patients	patient	NOUN
american_scientific_journal-766	403	50	with	with	ADP
american_scientific_journal-766	403	51	and	and	CCONJ
american_scientific_journal-766	403	52	without	without	ADP
american_scientific_journal-766	403	53	compensated	compensated	ADJ
american_scientific_journal-766	403	54	cirrhosis	cirrhosis	NOUN
american_scientific_journal-766	403	55	:	:	PUNCT
american_scientific_journal-766	403	56	results	result	NOUN
american_scientific_journal-766	403	57	from	from	ADP
american_scientific_journal-766	403	58	the	the	DET
american_scientific_journal-766	403	59	lonestar-2	lonestar-2	NUM
american_scientific_journal-766	403	60	study	study	NOUN
american_scientific_journal-766	403	61	,	,	PUNCT
american_scientific_journal-766	403	62	hepatology	hepatology	NOUN
american_scientific_journal-766	403	63	,	,	PUNCT
american_scientific_journal-766	403	64	58(suppl	58(suppl	PROPN
american_scientific_journal-766	403	65	4),1380a	4),1380a	NOUN
american_scientific_journal-766	403	66	.	.	PUNCT
american_scientific_journal-766	404	1	[	[	X
american_scientific_journal-766	404	2	81	81	NUM
american_scientific_journal-766	404	3	]	]	PUNCT
american_scientific_journal-766	404	4	gane	gane	NOUN
american_scientific_journal-766	404	5	ej	ej	PROPN
american_scientific_journal-766	404	6	,	,	PUNCT
american_scientific_journal-766	404	7	hyl	hyl	PROPN
american_scientific_journal-766	404	8	rh	rh	PROPN
american_scientific_journal-766	404	9	,	,	PUNCT
american_scientific_journal-766	404	10	an	an	DET
american_scientific_journal-766	404	11	d	d	NOUN
american_scientific_journal-766	404	12	,	,	PUNCT
american_scientific_journal-766	404	13	pang	pang	NOUN
american_scientific_journal-766	404	14	ps	ps	PROPN
american_scientific_journal-766	404	15	,	,	PUNCT
american_scientific_journal-766	404	16	symonds	symonds	PROPN
american_scientific_journal-766	404	17	wt	wt	PROPN
american_scientific_journal-766	404	18	,	,	PUNCT
american_scientific_journal-766	404	19	et	et	NOUN
american_scientific_journal-766	404	20	al,(2014	al,(2014	NOUN
american_scientific_journal-766	404	21	)	)	PUNCT
american_scientific_journal-766	404	22	,	,	PUNCT
american_scientific_journal-766	404	23	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	404	24	/	/	SYM
american_scientific_journal-766	404	25	ledipasvir	ledipasvir	PROPN
american_scientific_journal-766	404	26	fixed	fix	VERB
american_scientific_journal-766	404	27	dose	dose	NOUN
american_scientific_journal-766	404	28	combination	combination	NOUN
american_scientific_journal-766	404	29	is	be	AUX
american_scientific_journal-766	404	30	safe	safe	ADJ
american_scientific_journal-766	404	31	and	and	CCONJ
american_scientific_journal-766	404	32	effective	effective	ADJ
american_scientific_journal-766	404	33	in	in	ADP
american_scientific_journal-766	404	34	difficult	difficult	ADJ
american_scientific_journal-766	404	35	-	-	PUNCT
american_scientific_journal-766	404	36	to	to	ADP
american_scientific_journal-766	404	37	-	-	PUNCT
american_scientific_journal-766	404	38	treat	treat	VERB
american_scientific_journal-766	404	39	populations	population	NOUN
american_scientific_journal-766	404	40	including	include	VERB
american_scientific_journal-766	404	41	genotype-3	genotype-3	NUM
american_scientific_journal-766	404	42	patients	patient	NOUN
american_scientific_journal-766	404	43	,	,	PUNCT
american_scientific_journal-766	404	44	decompensated	decompensate	VERB
american_scientific_journal-766	404	45	genotype-1	genotype-1	NOUN
american_scientific_journal-766	404	46	patients	patient	NOUN
american_scientific_journal-766	404	47	,	,	PUNCT
american_scientific_journal-766	404	48	and	and	CCONJ
american_scientific_journal-766	404	49	genotype-1	genotype-1	NOUN
american_scientific_journal-766	404	50	patients	patient	NOUN
american_scientific_journal-766	404	51	with	with	ADP
american_scientific_journal-766	404	52	prior	prior	ADJ
american_scientific_journal-766	404	53	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	404	54	treatment	treatment	NOUN
american_scientific_journal-766	404	55	experience	experience	NOUN
american_scientific_journal-766	404	56	,	,	PUNCT
american_scientific_journal-766	404	57	j	j	PROPN
american_scientific_journal-766	404	58	hepatol	hepatol	ADJ
american_scientific_journal-766	404	59	,	,	PUNCT
american_scientific_journal-766	404	60	60	60	NUM
american_scientific_journal-766	404	61	:	:	PUNCT
american_scientific_journal-766	404	62	s3	s3	PROPN
american_scientific_journal-766	404	63	-	-	PUNCT
american_scientific_journal-766	404	64	s4	s4	NOUN
american_scientific_journal-766	404	65	.	.	PUNCT
american_scientific_journal-766	405	1	[	[	X
american_scientific_journal-766	405	2	82	82	X
american_scientific_journal-766	405	3	]	]	X
american_scientific_journal-766	405	4	fontana	fontana	PROPN
american_scientific_journal-766	405	5	r	r	PROPN
american_scientific_journal-766	405	6	,	,	PUNCT
american_scientific_journal-766	405	7	hughes	hughes	NOUN
american_scientific_journal-766	405	8	e	e	NOUN
american_scientific_journal-766	405	9	,	,	PUNCT
american_scientific_journal-766	405	10	bifano	bifano	NOUN
american_scientific_journal-766	405	11	m	m	PROPN
american_scientific_journal-766	405	12	,	,	PUNCT
american_scientific_journal-766	405	13	appelman	appelman	PROPN
american_scientific_journal-766	405	14	h	h	PROPN
american_scientific_journal-766	405	15	,	,	PUNCT
american_scientific_journal-766	405	16	dimitrova	dimitrova	PROPN
american_scientific_journal-766	405	17	d	d	PROPN
american_scientific_journal-766	405	18	,	,	PUNCT
american_scientific_journal-766	405	19	hindes	hindes	PROPN
american_scientific_journal-766	405	20	r	r	NOUN
american_scientific_journal-766	405	21	,	,	PUNCT
american_scientific_journal-766	405	22	et	et	PROPN
american_scientific_journal-766	405	23	al	al	PROPN
american_scientific_journal-766	405	24	.	.	PROPN
american_scientific_journal-766	405	25	,(2013	,(2013	PROPN
american_scientific_journal-766	405	26	)	)	PUNCT
american_scientific_journal-766	405	27	,	,	PUNCT
american_scientific_journal-766	405	28	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	405	29	and	and	CCONJ
american_scientific_journal-766	405	30	daclatasvir	daclatasvir	PROPN
american_scientific_journal-766	405	31	combination	combination	VERB
american_scientific_journal-766	405	32	therapy	therapy	NOUN
american_scientific_journal-766	405	33	in	in	ADP
american_scientific_journal-766	405	34	a	a	DET
american_scientific_journal-766	405	35	liver	liver	NOUN
american_scientific_journal-766	405	36	transplant	transplant	NOUN
american_scientific_journal-766	405	37	recipient	recipient	NOUN
american_scientific_journal-766	405	38	with	with	ADP
american_scientific_journal-766	405	39	severe	severe	ADJ
american_scientific_journal-766	405	40	recurrent	recurrent	ADJ
american_scientific_journal-766	405	41	cholestatic	cholestatic	ADJ
american_scientific_journal-766	405	42	hepatitis	hepatitis	NOUN
american_scientific_journal-766	405	43	c	c	PROPN
american_scientific_journal-766	405	44	,	,	PUNCT
american_scientific_journal-766	405	45	am	be	AUX
american_scientific_journal-766	405	46	j	j	PROPN
american_scientific_journal-766	405	47	transplant	transplant	NOUN
american_scientific_journal-766	405	48	,	,	PUNCT
american_scientific_journal-766	405	49	1601–05	1601–05	NUM
american_scientific_journal-766	405	50	[	[	X
american_scientific_journal-766	405	51	83	83	NUM
american_scientific_journal-766	405	52	]	]	X
american_scientific_journal-766	405	53	charlton	charlton	PROPN
american_scientific_journal-766	405	54	m	m	PROPN
american_scientific_journal-766	405	55	,	,	PUNCT
american_scientific_journal-766	405	56	gane	gane	NOUN
american_scientific_journal-766	405	57	e	e	NOUN
american_scientific_journal-766	405	58	,	,	PUNCT
american_scientific_journal-766	405	59	manns	manns	PROPN
american_scientific_journal-766	405	60	mp	mp	PROPN
american_scientific_journal-766	405	61	,	,	PUNCT
american_scientific_journal-766	405	62	brown	brown	PROPN
american_scientific_journal-766	405	63	rsj	rsj	NOUN
american_scientific_journal-766	405	64	,	,	PUNCT
american_scientific_journal-766	405	65	curry	curry	PROPN
american_scientific_journal-766	405	66	mp	mp	PROPN
american_scientific_journal-766	405	67	,	,	PUNCT
american_scientific_journal-766	405	68	et	et	PROPN
american_scientific_journal-766	405	69	al	al	PROPN
american_scientific_journal-766	405	70	.	.	PROPN
american_scientific_journal-766	405	71	,(2015	,(2015	PROPN
american_scientific_journal-766	405	72	)	)	PUNCT
american_scientific_journal-766	405	73	,	,	PUNCT
american_scientific_journal-766	405	74	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	405	75	and	and	CCONJ
american_scientific_journal-766	405	76	ribavirin	ribavirin	NOUN
american_scientific_journal-766	405	77	for	for	ADP
american_scientific_journal-766	405	78	treatment	treatment	NOUN
american_scientific_journal-766	405	79	of	of	ADP
american_scientific_journal-766	405	80	compensated	compensated	ADJ
american_scientific_journal-766	405	81	recurrent	recurrent	ADJ
american_scientific_journal-766	405	82	hepatitis	hepatitis	PROPN
american_scientific_journal-766	405	83	c	c	PROPN
american_scientific_journal-766	405	84	virus	virus	NOUN
american_scientific_journal-766	405	85	infection	infection	NOUN
american_scientific_journal-766	405	86	after	after	ADP
american_scientific_journal-766	405	87	liver	liver	NOUN
american_scientific_journal-766	405	88	transplantation	transplantation	NOUN
american_scientific_journal-766	405	89	.	.	PUNCT
american_scientific_journal-766	406	1	gastroenterology	gastroenterology	NOUN
american_scientific_journal-766	406	2	,	,	PUNCT
american_scientific_journal-766	406	3	148(1):108	148(1):108	NUM
american_scientific_journal-766	406	4	-	-	SYM
american_scientific_journal-766	406	5	17	17	NUM
american_scientific_journal-766	406	6	.	.	PUNCT
american_scientific_journal-766	407	1	[	[	X
american_scientific_journal-766	407	2	84	84	NUM
american_scientific_journal-766	407	3	]	]	X
american_scientific_journal-766	407	4	rodriguez	rodriguez	NOUN
american_scientific_journal-766	407	5	-	-	PUNCT
american_scientific_journal-766	407	6	torres	torres	PROPN
american_scientific_journal-766	407	7	m	m	PROPN
american_scientific_journal-766	407	8	,	,	PUNCT
american_scientific_journal-766	407	9	lawitz	lawitz	PROPN
american_scientific_journal-766	407	10	e	e	PROPN
american_scientific_journal-766	407	11	,	,	PUNCT
american_scientific_journal-766	407	12	kowdley	kowdley	PROPN
american_scientific_journal-766	407	13	kv	kv	PROPN
american_scientific_journal-766	407	14	,	,	PUNCT
american_scientific_journal-766	407	15	nelson	nelson	PROPN
american_scientific_journal-766	407	16	dr	dr	PROPN
american_scientific_journal-766	407	17	,	,	PUNCT
american_scientific_journal-766	407	18	dejesus	dejesus	PROPN
american_scientific_journal-766	407	19	e	e	PROPN
american_scientific_journal-766	407	20	,	,	PUNCT
american_scientific_journal-766	407	21	mc	mc	PROPN
american_scientific_journal-766	407	22	-	-	PUNCT
american_scientific_journal-766	407	23	hutchison	hutchison	PROPN
american_scientific_journal-766	407	24	jg	jg	PROPN
american_scientific_journal-766	407	25	,	,	PUNCT
american_scientific_journal-766	407	26	et	et	NOUN
american_scientific_journal-766	407	27	al,(2013	al,(2013	PROPN
american_scientific_journal-766	407	28	)	)	PUNCT
american_scientific_journal-766	407	29	,	,	PUNCT
american_scientific_journal-766	407	30	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	407	31	(	(	PUNCT
american_scientific_journal-766	407	32	gs-7977	gs-7977	PROPN
american_scientific_journal-766	407	33	)	)	PUNCT
american_scientific_journal-766	407	34	plus	plus	CCONJ
american_scientific_journal-766	407	35	peg	peg	NOUN
american_scientific_journal-766	407	36	-	-	PUNCT
american_scientific_journal-766	407	37	interferon	interferon	NOUN
american_scientific_journal-766	407	38	/	/	SYM
american_scientific_journal-766	407	39	ribavirin	ribavirin	NOUN
american_scientific_journal-766	407	40	in	in	ADP
american_scientific_journal-766	407	41	treatment	treatment	NOUN
american_scientific_journal-766	407	42	-	-	PUNCT
american_scientific_journal-766	407	43	naïve	naïve	ADJ
american_scientific_journal-766	407	44	patients	patient	NOUN
american_scientific_journal-766	407	45	with	with	ADP
american_scientific_journal-766	407	46	hcv	hcv	NOUN
american_scientific_journal-766	407	47	genotype	genotype	NOUN
american_scientific_journal-766	407	48	1	1	NUM
american_scientific_journal-766	407	49	:	:	PUNCT
american_scientific_journal-766	407	50	a	a	DET
american_scientific_journal-766	407	51	randomized	randomized	ADJ
american_scientific_journal-766	407	52	,	,	PUNCT
american_scientific_journal-766	407	53	28	28	NUM
american_scientific_journal-766	407	54	-	-	PUNCT
american_scientific_journal-766	407	55	day	day	NOUN
american_scientific_journal-766	407	56	,	,	PUNCT
american_scientific_journal-766	407	57	dose	dose	NOUN
american_scientific_journal-766	407	58	-	-	PUNCT
american_scientific_journal-766	407	59	ranging	range	VERB
american_scientific_journal-766	407	60	trial	trial	NOUN
american_scientific_journal-766	407	61	,	,	PUNCT
american_scientific_journal-766	407	62	j	j	PROPN
american_scientific_journal-766	407	63	hepatol	hepatol	ADJ
american_scientific_journal-766	407	64	.	.	PUNCT
american_scientific_journal-766	408	1	58,663–68	58,663–68	X
american_scientific_journal-766	408	2	.	.	PUNCT
american_scientific_journal-766	409	1	[	[	X
american_scientific_journal-766	409	2	85	85	NUM
american_scientific_journal-766	409	3	]	]	X
american_scientific_journal-766	409	4	younossi	younossi	PROPN
american_scientific_journal-766	409	5	z	z	PROPN
american_scientific_journal-766	409	6	,	,	PUNCT
american_scientific_journal-766	409	7	stepanova	stepanova	PROPN
american_scientific_journal-766	409	8	m	m	PROPN
american_scientific_journal-766	409	9	,	,	PUNCT
american_scientific_journal-766	409	10	mir	mir	PROPN
american_scientific_journal-766	409	11	h	h	PROPN
american_scientific_journal-766	409	12	,	,	PUNCT
american_scientific_journal-766	409	13	jacobson	jacobson	PROPN
american_scientific_journal-766	409	14	i	i	PRON
american_scientific_journal-766	409	15	,	,	PUNCT
american_scientific_journal-766	409	16	gane	gane	NOUN
american_scientific_journal-766	409	17	e	e	NOUN
american_scientific_journal-766	409	18	,	,	PUNCT
american_scientific_journal-766	409	19	nader	nader	PROPN
american_scientific_journal-766	409	20	f	f	PROPN
american_scientific_journal-766	409	21	,	,	PUNCT
american_scientific_journal-766	409	22	et	et	PROPN
american_scientific_journal-766	409	23	al	al	PROPN
american_scientific_journal-766	409	24	.	.	PROPN
american_scientific_journal-766	409	25	,	,	PUNCT
american_scientific_journal-766	409	26	(	(	PUNCT
american_scientific_journal-766	409	27	2013	2013	NUM
american_scientific_journal-766	409	28	)	)	PUNCT
american_scientific_journal-766	409	29	,	,	PUNCT
american_scientific_journal-766	409	30	minimal	minimal	ADJ
american_scientific_journal-766	409	31	impact	impact	NOUN
american_scientific_journal-766	409	32	of	of	ADP
american_scientific_journal-766	409	33	22	22	NUM
american_scientific_journal-766	409	34	http://dx.doi.org/10.1016/j.jare.2014.11.004	http://dx.doi.org/10.1016/j.jare.2014.11.004	NOUN
american_scientific_journal-766	409	35	american	american	ADJ
american_scientific_journal-766	409	36	scientific	scientific	ADJ
american_scientific_journal-766	409	37	research	research	NOUN
american_scientific_journal-766	409	38	journal	journal	NOUN
american_scientific_journal-766	409	39	for	for	ADP
american_scientific_journal-766	409	40	engineering	engineering	NOUN
american_scientific_journal-766	409	41	,	,	PUNCT
american_scientific_journal-766	409	42	technology	technology	NOUN
american_scientific_journal-766	409	43	,	,	PUNCT
american_scientific_journal-766	409	44	and	and	CCONJ
american_scientific_journal-766	409	45	sciences	science	NOUN
american_scientific_journal-766	409	46	(	(	PUNCT
american_scientific_journal-766	409	47	asrjets	asrjet	NOUN
american_scientific_journal-766	409	48	)	)	PUNCT
american_scientific_journal-766	409	49	(	(	PUNCT
american_scientific_journal-766	409	50	2015	2015	NUM
american_scientific_journal-766	409	51	)	)	PUNCT
american_scientific_journal-766	409	52	volume	volume	NOUN
american_scientific_journal-766	409	53	13	13	NUM
american_scientific_journal-766	409	54	,	,	PUNCT
american_scientific_journal-766	409	55	no	no	DET
american_scientific_journal-766	409	56	1	1	NUM
american_scientific_journal-766	409	57	,	,	PUNCT
american_scientific_journal-766	409	58	pp	pp	ADV
american_scientific_journal-766	409	59	1	1	NUM
american_scientific_journal-766	409	60	-	-	SYM
american_scientific_journal-766	409	61	23	23	NUM
american_scientific_journal-766	409	62	sofosbuvir	sofosbuvir	NOUN
american_scientific_journal-766	409	63	+	+	CCONJ
american_scientific_journal-766	409	64	ribavirin	ribavirin	NOUN
american_scientific_journal-766	409	65	on	on	ADP
american_scientific_journal-766	409	66	health	health	NOUN
american_scientific_journal-766	409	67	related	relate	VERB
american_scientific_journal-766	409	68	quality	quality	NOUN
american_scientific_journal-766	409	69	of	of	ADP
american_scientific_journal-766	409	70	life	life	NOUN
american_scientific_journal-766	409	71	(	(	PUNCT
american_scientific_journal-766	409	72	hrql	hrql	NOUN
american_scientific_journal-766	409	73	)	)	PUNCT
american_scientific_journal-766	409	74	compared	compare	VERB
american_scientific_journal-766	409	75	to	to	ADP
american_scientific_journal-766	409	76	pegylated	pegylate	VERB
american_scientific_journal-766	409	77	interferon	interferon	NOUN
american_scientific_journal-766	409	78	+	+	CCONJ
american_scientific_journal-766	409	79	ribavirin	ribavirin	NOUN
american_scientific_journal-766	409	80	for	for	ADP
american_scientific_journal-766	409	81	chronic	chronic	ADJ
american_scientific_journal-766	409	82	hepatitis	hepatitis	NOUN
american_scientific_journal-766	409	83	c	c	NOUN
american_scientific_journal-766	409	84	:	:	PUNCT
american_scientific_journal-766	409	85	results	result	NOUN
american_scientific_journal-766	409	86	from	from	ADP
american_scientific_journal-766	409	87	fission	fission	NOUN
american_scientific_journal-766	409	88	+	+	CCONJ
american_scientific_journal-766	409	89	positron	positron	NOUN
american_scientific_journal-766	409	90	trials	trial	NOUN
american_scientific_journal-766	409	91	,	,	PUNCT
american_scientific_journal-766	409	92	j	j	PROPN
american_scientific_journal-766	409	93	hepatol	hepatol	ADJ
american_scientific_journal-766	409	94	,	,	PUNCT
american_scientific_journal-766	409	95	58(s567	58(s567	NUM
american_scientific_journal-766	409	96	–	–	PUNCT
american_scientific_journal-766	409	97	s577	s577	PROPN
american_scientific_journal-766	409	98	)	)	PUNCT
american_scientific_journal-766	409	99	,	,	PUNCT
american_scientific_journal-766	409	100	abstract	abstract	ADJ
american_scientific_journal-766	409	101	1431	1431	NUM
american_scientific_journal-766	409	102	[	[	X
american_scientific_journal-766	409	103	86	86	NUM
american_scientific_journal-766	409	104	]	]	PUNCT
american_scientific_journal-766	409	105	us	us	PROPN
american_scientific_journal-766	409	106	food	food	NOUN
american_scientific_journal-766	409	107	and	and	CCONJ
american_scientific_journal-766	409	108	drug	drug	NOUN
american_scientific_journal-766	409	109	administration,(2015	administration,(2015	NOUN
american_scientific_journal-766	409	110	)	)	PUNCT
american_scientific_journal-766	409	111	,	,	PUNCT
american_scientific_journal-766	409	112	fda	fda	PROPN
american_scientific_journal-766	409	113	drug	drug	PROPN
american_scientific_journal-766	409	114	safety	safety	NOUN
american_scientific_journal-766	409	115	communication	communication	NOUN
american_scientific_journal-766	409	116	.	.	PUNCT
american_scientific_journal-766	410	1	http://www.fda.gov/drugs/drugsafety/ucm439484.htm	http://www.fda.gov/drugs/drugsafety/ucm439484.htm	PROPN
american_scientific_journal-766	411	1	[	[	X
american_scientific_journal-766	411	2	87	87	NUM
american_scientific_journal-766	411	3	]	]	PUNCT
american_scientific_journal-766	411	4	karageorgopoulos	karageorgopoulos	PROPN
american_scientific_journal-766	411	5	de	de	PROPN
american_scientific_journal-766	411	6	,	,	PUNCT
american_scientific_journal-766	411	7	el	el	PROPN
american_scientific_journal-766	411	8	-	-	PUNCT
american_scientific_journal-766	411	9	sherif	sherif	PROPN
american_scientific_journal-766	411	10	o	o	PROPN
american_scientific_journal-766	411	11	,	,	PUNCT
american_scientific_journal-766	411	12	bhagani	bhagani	PROPN
american_scientific_journal-766	411	13	s	s	PROPN
american_scientific_journal-766	411	14	,	,	PUNCT
american_scientific_journal-766	411	15	khoo	khoo	PROPN
american_scientific_journal-766	411	16	sh,(2014	sh,(2014	NOUN
american_scientific_journal-766	411	17	)	)	PUNCT
american_scientific_journal-766	411	18	drug	drug	NOUN
american_scientific_journal-766	411	19	interactions	interaction	NOUN
american_scientific_journal-766	411	20	between	between	ADP
american_scientific_journal-766	411	21	antiretrovirals	antiretroviral	NOUN
american_scientific_journal-766	411	22	and	and	CCONJ
american_scientific_journal-766	411	23	new	new	ADJ
american_scientific_journal-766	411	24	or	or	CCONJ
american_scientific_journal-766	411	25	emerging	emerge	VERB
american_scientific_journal-766	411	26	direct	direct	ADJ
american_scientific_journal-766	411	27	-	-	PUNCT
american_scientific_journal-766	411	28	acting	act	VERB
american_scientific_journal-766	411	29	antivirals	antiviral	NOUN
american_scientific_journal-766	411	30	in	in	ADP
american_scientific_journal-766	411	31	hiv	hiv	PROPN
american_scientific_journal-766	411	32	/	/	SYM
american_scientific_journal-766	411	33	hepatitis	hepatitis	PROPN
american_scientific_journal-766	411	34	c	c	PROPN
american_scientific_journal-766	411	35	virus	virus	NOUN
american_scientific_journal-766	411	36	confection	confection	NOUN
american_scientific_journal-766	411	37	,	,	PUNCT
american_scientific_journal-766	411	38	curr	curr	PROPN
american_scientific_journal-766	411	39	opin	opin	PROPN
american_scientific_journal-766	411	40	infect	infect	PROPN
american_scientific_journal-766	411	41	dis	dis	PROPN
american_scientific_journal-766	411	42	,	,	PUNCT
american_scientific_journal-766	411	43	27(1	27(1	NUM
american_scientific_journal-766	411	44	)	)	PUNCT
american_scientific_journal-766	411	45	,	,	PUNCT
american_scientific_journal-766	411	46	36	36	NUM
american_scientific_journal-766	411	47	-	-	SYM
american_scientific_journal-766	411	48	45	45	NUM
american_scientific_journal-766	411	49	.	.	PUNCT
american_scientific_journal-766	412	1	[	[	X
american_scientific_journal-766	412	2	88	88	NUM
american_scientific_journal-766	412	3	]	]	X
american_scientific_journal-766	412	4	levin	levin	PROPN
american_scientific_journal-766	412	5	j	j	PROPN
american_scientific_journal-766	412	6	(	(	PUNCT
american_scientific_journal-766	412	7	2012	2012	NUM
american_scientific_journal-766	412	8	)	)	PUNCT
american_scientific_journal-766	412	9	,	,	PUNCT
american_scientific_journal-766	412	10	gs-7977	gs-7977	PROPN
american_scientific_journal-766	412	11	and	and	CCONJ
american_scientific_journal-766	412	12	hiv	hiv	PROPN
american_scientific_journal-766	412	13	arts	art	NOUN
american_scientific_journal-766	412	14	pk	pk	VERB
american_scientific_journal-766	412	15	no	no	DET
american_scientific_journal-766	412	16	clinically	clinically	ADV
american_scientific_journal-766	412	17	significant	significant	ADJ
american_scientific_journal-766	412	18	pharmacokinetic	pharmacokinetic	ADJ
american_scientific_journal-766	412	19	interactions	interaction	NOUN
american_scientific_journal-766	412	20	between	between	ADP
american_scientific_journal-766	412	21	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	412	22	(	(	PUNCT
american_scientific_journal-766	412	23	gs-7977	gs-7977	PROPN
american_scientific_journal-766	412	24	)	)	PUNCT
american_scientific_journal-766	412	25	and	and	CCONJ
american_scientific_journal-766	412	26	hiv	hiv	PROPN
american_scientific_journal-766	412	27	antiretro	antiretro	VERB
american_scientific_journal-766	412	28	virals	viral	NOUN
american_scientific_journal-766	412	29	atripla	atripla	NOUN
american_scientific_journal-766	412	30	,	,	PUNCT
american_scientific_journal-766	412	31	rilpivirine	rilpivirine	NOUN
american_scientific_journal-766	412	32	,	,	PUNCT
american_scientific_journal-766	412	33	darunavir	darunavir	PROPN
american_scientific_journal-766	412	34	/	/	SYM
american_scientific_journal-766	412	35	ritonavir	ritonavir	PROPN
american_scientific_journal-766	412	36	,	,	PUNCT
american_scientific_journal-766	412	37	or	or	CCONJ
american_scientific_journal-766	412	38	raltegravir	raltegravir	PROPN
american_scientific_journal-766	412	39	in	in	ADP
american_scientific_journal-766	412	40	healthy	healthy	ADJ
american_scientific_journal-766	412	41	volunteers	volunteer	NOUN
american_scientific_journal-766	412	42	.	.	PUNCT
american_scientific_journal-766	413	1	aasld63rd	aasld63rd	PROPN
american_scientific_journal-766	413	2	annual	annual	ADJ
american_scientific_journal-766	413	3	meeting	meeting	NOUN
american_scientific_journal-766	413	4	of	of	ADP
american_scientific_journal-766	413	5	the	the	DET
american_scientific_journal-766	413	6	american	american	PROPN
american_scientific_journal-766	413	7	association	association	PROPN
american_scientific_journal-766	413	8	for	for	ADP
american_scientific_journal-766	413	9	the	the	DET
american_scientific_journal-766	413	10	study	study	NOUN
american_scientific_journal-766	413	11	of	of	ADP
american_scientific_journal-766	413	12	liver	liver	NOUN
american_scientific_journal-766	413	13	diseases	disease	NOUN
american_scientific_journal-766	413	14	.	.	PUNCT
american_scientific_journal-766	414	1	23	23	NUM
american_scientific_journal-766	414	2	2.1.1	2.1.1	NUM
american_scientific_journal-766	414	3	.	.	PUNCT
american_scientific_journal-766	415	1	interferon	interferon	ADJ
american_scientific_journal-766	415	2	monotherapy	monotherapy	NOUN
american_scientific_journal-766	415	3	2.1.2.peg	2.1.2.peg	NOUN
american_scientific_journal-766	415	4	-	-	PUNCT
american_scientific_journal-766	415	5	ifn	ifn	NOUN
american_scientific_journal-766	415	6	therapy	therapy	NOUN
american_scientific_journal-766	415	7	with	with	ADP
american_scientific_journal-766	415	8	ribavirin	ribavirin	NOUN
american_scientific_journal-766	415	9	2.2.1	2.2.1	NUM
american_scientific_journal-766	415	10	.	.	PUNCT
american_scientific_journal-766	416	1	ns3/4a	ns3/4a	NOUN
american_scientific_journal-766	416	2	protease	protease	NOUN
american_scientific_journal-766	416	3	inhibitors	inhibitor	VERB
american_scientific_journal-766	416	4	the	the	DET
american_scientific_journal-766	416	5	ns3	ns3	NOUN
american_scientific_journal-766	416	6	protease	protease	NOUN
american_scientific_journal-766	416	7	is	be	AUX
american_scientific_journal-766	416	8	an	an	DET
american_scientific_journal-766	416	9	enzyme	enzyme	NOUN
american_scientific_journal-766	416	10	that	that	PRON
american_scientific_journal-766	416	11	catalyzes	catalyze	VERB
american_scientific_journal-766	416	12	the	the	DET
american_scientific_journal-766	416	13	post	post	ADJ
american_scientific_journal-766	416	14	-	-	ADJ
american_scientific_journal-766	416	15	transcriptional	transcriptional	ADJ
american_scientific_journal-766	416	16	processing	processing	NOUN
american_scientific_journal-766	416	17	of	of	ADP
american_scientific_journal-766	416	18	proteins	protein	NOUN
american_scientific_journal-766	416	19	important	important	ADJ
american_scientific_journal-766	416	20	for	for	ADP
american_scientific_journal-766	416	21	viral	viral	ADJ
american_scientific_journal-766	416	22	replication	replication	NOUN
american_scientific_journal-766	416	23	.	.	PUNCT
american_scientific_journal-766	417	1	ns4a	ns4a	NOUN
american_scientific_journal-766	417	2	is	be	AUX
american_scientific_journal-766	417	3	a	a	DET
american_scientific_journal-766	417	4	cofactor	cofactor	NOUN
american_scientific_journal-766	417	5	that	that	PRON
american_scientific_journal-766	417	6	works	work	VERB
american_scientific_journal-766	417	7	with	with	ADP
american_scientific_journal-766	417	8	ns3	ns3	NOUN
american_scientific_journal-766	417	9	to	to	PART
american_scientific_journal-766	417	10	expedite	expedite	VERB
american_scientific_journal-766	417	11	this	this	DET
american_scientific_journal-766	417	12	process	process	NOUN
american_scientific_journal-766	417	13	.	.	PUNCT
american_scientific_journal-766	418	1	the	the	DET
american_scientific_journal-766	418	2	serine	serine	ADJ
american_scientific_journal-766	418	3	protease	protease	NOUN
american_scientific_journal-766	418	4	inhibitors	inhibitor	NOUN
american_scientific_journal-766	418	5	telaprevir	telaprevir	PRON
american_scientific_journal-766	418	6	is	be	AUX
american_scientific_journal-766	418	7	a	a	DET
american_scientific_journal-766	418	8	linear	linear	ADJ
american_scientific_journal-766	418	9	peptid	peptid	NOUN
american_scientific_journal-766	418	10	...	...	PUNCT
american_scientific_journal-766	419	1	2.2.1.1	2.2.1.1	X
american_scientific_journal-766	419	2	.	.	PUNCT
american_scientific_journal-766	419	3	telaprevir	telaprevir	PROPN
american_scientific_journal-766	419	4	and	and	CCONJ
american_scientific_journal-766	419	5	boceprevir	boceprevir	VERB
american_scientific_journal-766	419	6	two	two	NUM
american_scientific_journal-766	419	7	first	first	ADJ
american_scientific_journal-766	419	8	-	-	PUNCT
american_scientific_journal-766	419	9	generation	generation	NOUN
american_scientific_journal-766	419	10	,	,	PUNCT
american_scientific_journal-766	419	11	linear	linear	ADJ
american_scientific_journal-766	419	12	ns3/4a	ns3/4a	ADV
american_scientific_journal-766	419	13	pis	pis	NOUN
american_scientific_journal-766	419	14	,	,	PUNCT
american_scientific_journal-766	419	15	boceprevir	boceprevir	NOUN
american_scientific_journal-766	419	16	and	and	CCONJ
american_scientific_journal-766	419	17	telaprevir	telaprevir	PROPN
american_scientific_journal-766	419	18	,	,	PUNCT
american_scientific_journal-766	419	19	were	be	AUX
american_scientific_journal-766	419	20	approved	approve	VERB
american_scientific_journal-766	419	21	in	in	ADP
american_scientific_journal-766	419	22	the	the	DET
american_scientific_journal-766	419	23	usa	usa	PROPN
american_scientific_journal-766	419	24	and	and	CCONJ
american_scientific_journal-766	419	25	europe	europe	PROPN
american_scientific_journal-766	419	26	in	in	ADP
american_scientific_journal-766	419	27	2011	2011	NUM
american_scientific_journal-766	419	28	for	for	ADP
american_scientific_journal-766	419	29	clinical	clinical	ADJ
american_scientific_journal-766	419	30	use	use	NOUN
american_scientific_journal-766	419	31	in	in	ADP
american_scientific_journal-766	419	32	patients	patient	NOUN
american_scientific_journal-766	419	33	with	with	ADP
american_scientific_journal-766	419	34	genotype	genotype	NOUN
american_scientific_journal-766	419	35	1	1	NUM
american_scientific_journal-766	419	36	,	,	PUNCT
american_scientific_journal-766	419	37	while	while	SCONJ
american_scientific_journal-766	419	38	numerous	numerous	ADJ
american_scientific_journal-766	419	39	new	new	ADJ
american_scientific_journal-766	419	40	ns3/4	ns3/4	PROPN
american_scientific_journal-766	419	41	pis	pis	NOUN
american_scientific_journal-766	419	42	are	be	AUX
american_scientific_journal-766	419	43	currently	currently	ADV
american_scientific_journal-766	419	44	under	under	ADP
american_scientific_journal-766	419	45	evaluation	evaluation	NOUN
american_scientific_journal-766	419	46	in	in	ADP
american_scientific_journal-766	419	47	clinical	clinical	ADJ
american_scientific_journal-766	419	48	trials	trial	NOUN
american_scientific_journal-766	419	49	.	.	PUNCT
american_scientific_journal-766	420	1	however	however	ADV
american_scientific_journal-766	420	2	,	,	PUNCT
american_scientific_journal-766	420	3	thes	thes	X
american_scientific_journal-766	420	4	...	...	PUNCT
american_scientific_journal-766	421	1	2.2.1.3	2.2.1.3	X
american_scientific_journal-766	421	2	.	.	PUNCT
american_scientific_journal-766	421	3	faldaprevir	faldaprevir	PROPN
american_scientific_journal-766	421	4	;	;	PUNCT
american_scientific_journal-766	422	1	2.2.2	2.2.2	X
american_scientific_journal-766	422	2	.	.	PUNCT
american_scientific_journal-766	423	1	ns5a	ns5a	ADJ
american_scientific_journal-766	423	2	inhibitors	inhibitor	NOUN
american_scientific_journal-766	423	3	;	;	PUNCT
american_scientific_journal-766	423	4	the	the	DET
american_scientific_journal-766	423	5	ns5a	ns5a	ADJ
american_scientific_journal-766	423	6	protein	protein	NOUN
american_scientific_journal-766	423	7	is	be	AUX
american_scientific_journal-766	423	8	a	a	DET
american_scientific_journal-766	423	9	regulator	regulator	NOUN
american_scientific_journal-766	423	10	of	of	ADP
american_scientific_journal-766	423	11	replication	replication	NOUN
american_scientific_journal-766	423	12	.	.	PUNCT
american_scientific_journal-766	424	1	ns5a	ns5a	ADJ
american_scientific_journal-766	424	2	inhibitors	inhibitor	NOUN
american_scientific_journal-766	424	3	have	have	VERB
american_scientific_journal-766	424	4	high	high	ADJ
american_scientific_journal-766	424	5	antiviral	antiviral	ADJ
american_scientific_journal-766	424	6	activity	activity	NOUN
american_scientific_journal-766	424	7	against	against	ADP
american_scientific_journal-766	424	8	different	different	ADJ
american_scientific_journal-766	424	9	genotypes	genotype	NOUN
american_scientific_journal-766	424	10	,	,	PUNCT
american_scientific_journal-766	424	11	but	but	CCONJ
american_scientific_journal-766	424	12	a	a	DET
american_scientific_journal-766	424	13	low	low	ADJ
american_scientific_journal-766	424	14	genetic	genetic	ADJ
american_scientific_journal-766	424	15	barrier	barrier	NOUN
american_scientific_journal-766	424	16	to	to	ADP
american_scientific_journal-766	424	17	resistance	resistance	NOUN
american_scientific_journal-766	424	18	.	.	PUNCT
american_scientific_journal-766	425	1	resistance	resistance	NOUN
american_scientific_journal-766	425	2	variants	variant	NOUN
american_scientific_journal-766	425	3	to	to	ADP
american_scientific_journal-766	425	4	ns5a	ns5a	VERB
american_scientific_journal-766	425	5	inhibitors	inhibitor	NOUN
american_scientific_journal-766	425	6	are	be	AUX
american_scientific_journal-766	425	7	not	not	PART
american_scientific_journal-766	425	8	associated	associate	VERB
american_scientific_journal-766	425	9	with	with	ADP
american_scientific_journal-766	425	10	impaired	impaired	ADJ
american_scientific_journal-766	425	11	viral	viral	ADJ
american_scientific_journal-766	425	12	replicatio	replicatio	NOUN
american_scientific_journal-766	425	13	...	...	PUNCT
american_scientific_journal-766	426	1	2.2.2.1	2.2.2.1	X
american_scientific_journal-766	426	2	.	.	PUNCT
american_scientific_journal-766	426	3	daclatasvir	daclatasvir	PROPN
american_scientific_journal-766	426	4	2.2.2.2	2.2.2.2	NUM
american_scientific_journal-766	426	5	.	.	PROPN
american_scientific_journal-766	426	6	ledipasvir	ledipasvir	PROPN
american_scientific_journal-766	426	7	2.2.2.3	2.2.2.3	NUM
american_scientific_journal-766	426	8	.	.	PUNCT
american_scientific_journal-766	427	1	cyclophilin	cyclophilin	PROPN
american_scientific_journal-766	427	2	a	a	DET
american_scientific_journal-766	427	3	inhibitors	inhibitor	NOUN
american_scientific_journal-766	427	4	cyclophilins	cyclophilin	NOUN
american_scientific_journal-766	427	5	are	be	AUX
american_scientific_journal-766	427	6	host	host	NOUN
american_scientific_journal-766	427	7	proteins	protein	NOUN
american_scientific_journal-766	427	8	involved	involve	VERB
american_scientific_journal-766	427	9	in	in	ADP
american_scientific_journal-766	427	10	protein	protein	NOUN
american_scientific_journal-766	427	11	folding	folding	NOUN
american_scientific_journal-766	427	12	.	.	PUNCT
american_scientific_journal-766	428	1	they	they	PRON
american_scientific_journal-766	428	2	play	play	VERB
american_scientific_journal-766	428	3	an	an	DET
american_scientific_journal-766	428	4	important	important	ADJ
american_scientific_journal-766	428	5	role	role	NOUN
american_scientific_journal-766	428	6	in	in	ADP
american_scientific_journal-766	428	7	the	the	DET
american_scientific_journal-766	428	8	hcv	hcv	NOUN
american_scientific_journal-766	428	9	lifecycle	lifecycle	NOUN
american_scientific_journal-766	428	10	as	as	ADP
american_scientific_journal-766	428	11	regulators	regulator	NOUN
american_scientific_journal-766	428	12	of	of	ADP
american_scientific_journal-766	428	13	replication	replication	NOUN
american_scientific_journal-766	428	14	.	.	PUNCT
american_scientific_journal-766	429	1	the	the	DET
american_scientific_journal-766	429	2	cyclophilin	cyclophilin	PROPN
american_scientific_journal-766	429	3	inhibitor	inhibitor	NOUN
american_scientific_journal-766	429	4	alisporivir	alisporivir	PROPN
american_scientific_journal-766	429	5	(	(	PUNCT
american_scientific_journal-766	429	6	deb-025	deb-025	NOUN
american_scientific_journal-766	429	7	)	)	PUNCT
american_scientific_journal-766	429	8	is	be	AUX
american_scientific_journal-766	429	9	a	a	DET
american_scientific_journal-766	429	10	cyclosporine	cyclosporine	ADJ
american_scientific_journal-766	429	11	analog	analog	NOUN
american_scientific_journal-766	429	12	without	without	ADP
american_scientific_journal-766	429	13	its	its	PRON
american_scientific_journal-766	429	14	immunosuppressive	immunosuppressive	ADJ
american_scientific_journal-766	429	15	propertie	propertie	NOUN
american_scientific_journal-766	429	16	...	...	PUNCT
american_scientific_journal-766	429	17	2.2.3	2.2.3	X
american_scientific_journal-766	429	18	.	.	PUNCT
american_scientific_journal-766	430	1	ns5b	ns5b	ADJ
american_scientific_journal-766	430	2	polymerase	polymerase	NOUN
american_scientific_journal-766	430	3	inhibitors	inhibitor	NOUN
american_scientific_journal-766	430	4	there	there	PRON
american_scientific_journal-766	430	5	are	be	VERB
american_scientific_journal-766	430	6	two	two	NUM
american_scientific_journal-766	430	7	categories	category	NOUN
american_scientific_journal-766	430	8	of	of	ADP
american_scientific_journal-766	430	9	ns5b	ns5b	ADJ
american_scientific_journal-766	430	10	polymerase	polymerase	NOUN
american_scientific_journal-766	430	11	inhibitors	inhibitor	NOUN
american_scientific_journal-766	430	12	:	:	PUNCT
american_scientific_journal-766	430	13	nucleos(t)ide	nucleos(t)ide	ADV
american_scientific_journal-766	430	14	(	(	PUNCT
american_scientific_journal-766	430	15	nis	nis	NOUN
american_scientific_journal-766	430	16	)	)	PUNCT
american_scientific_journal-766	430	17	and	and	CCONJ
american_scientific_journal-766	430	18	non	non	ADJ
american_scientific_journal-766	430	19	-	-	ADJ
american_scientific_journal-766	430	20	nucleoside	nucleoside	ADJ
american_scientific_journal-766	430	21	inhibitors	inhibitor	NOUN
american_scientific_journal-766	430	22	(	(	PUNCT
american_scientific_journal-766	430	23	nnis	nnis	PROPN
american_scientific_journal-766	430	24	)	)	PUNCT
american_scientific_journal-766	430	25	(	(	PUNCT
american_scientific_journal-766	430	26	table	table	NOUN
american_scientific_journal-766	430	27	1	1	NUM
american_scientific_journal-766	430	28	)	)	PUNCT
american_scientific_journal-766	430	29	.	.	PUNCT
american_scientific_journal-766	431	1	nis	nis	PROPN
american_scientific_journal-766	431	2	mimic	mimic	VERB
american_scientific_journal-766	431	3	the	the	DET
american_scientific_journal-766	431	4	naturally	naturally	ADV
american_scientific_journal-766	431	5	occurring	occur	VERB
american_scientific_journal-766	431	6	nucleos(t)ides	nucleos(t)ide	NOUN
american_scientific_journal-766	431	7	and	and	CCONJ
american_scientific_journal-766	431	8	thus	thus	ADV
american_scientific_journal-766	431	9	are	be	AUX
american_scientific_journal-766	431	10	incorporated	incorporate	VERB
american_scientific_journal-766	431	11	into	into	ADP
american_scientific_journal-766	431	12	the	the	DET
american_scientific_journal-766	431	13	nascent	nascent	ADJ
american_scientific_journal-766	431	14	rna	rna	NOUN
american_scientific_journal-766	431	15	chain	chain	NOUN
american_scientific_journal-766	431	16	causing	cause	VERB
american_scientific_journal-766	431	17	premature	premature	ADJ
american_scientific_journal-766	431	18	chain	chain	NOUN
american_scientific_journal-766	431	19	t	t	PROPN
american_scientific_journal-766	431	20	...	...	PUNCT
american_scientific_journal-766	431	21	several	several	ADJ
american_scientific_journal-766	431	22	nonnucleoside	nonnucleoside	ADJ
american_scientific_journal-766	431	23	inhibitors	inhibitor	NOUN
american_scientific_journal-766	431	24	(	(	PUNCT
american_scientific_journal-766	431	25	nnis	nnis	PROPN
american_scientific_journal-766	431	26	)	)	PUNCT
american_scientific_journal-766	431	27	of	of	ADP
american_scientific_journal-766	431	28	the	the	DET
american_scientific_journal-766	431	29	hcv	hcv	NOUN
american_scientific_journal-766	431	30	polymerase	polymerase	NOUN
american_scientific_journal-766	431	31	can	can	AUX
american_scientific_journal-766	431	32	prevent	prevent	VERB
american_scientific_journal-766	431	33	either	either	CCONJ
american_scientific_journal-766	431	34	de	de	PROPN
american_scientific_journal-766	431	35	novo	novo	NOUN
american_scientific_journal-766	431	36	initiated	initiate	VERB
american_scientific_journal-766	431	37	rna	rna	NOUN
american_scientific_journal-766	431	38	synthesis	synthesis	NOUN
american_scientific_journal-766	431	39	,	,	PUNCT
american_scientific_journal-766	431	40	primer	primer	NOUN
american_scientific_journal-766	431	41	-	-	PUNCT
american_scientific_journal-766	431	42	extended	extend	VERB
american_scientific_journal-766	431	43	rna	rna	NOUN
american_scientific_journal-766	431	44	synthesis	synthesis	NOUN
american_scientific_journal-766	431	45	,	,	PUNCT
american_scientific_journal-766	431	46	or	or	CCONJ
american_scientific_journal-766	431	47	both	both	PRON
american_scientific_journal-766	431	48	.	.	PUNCT
american_scientific_journal-766	432	1	these	these	DET
american_scientific_journal-766	432	2	nnis	nnis	ADJ
american_scientific_journal-766	432	3	inhibitors	inhibitor	NOUN
american_scientific_journal-766	432	4	achieve	achieve	VERB
american_scientific_journal-766	432	5	polymerase	polymerase	NOUN
american_scientific_journal-766	432	6	inhibition	inhibition	NOUN
american_scientific_journal-766	432	7	by	by	ADP
american_scientific_journal-766	432	8	binding	bind	VERB
american_scientific_journal-766	432	9	to	to	ADP
american_scientific_journal-766	432	10	one	one	NUM
american_scientific_journal-766	432	11	of	of	ADP
american_scientific_journal-766	432	12	the	the	DET
american_scientific_journal-766	432	13	at	at	ADV
american_scientific_journal-766	432	14	least	least	ADJ
american_scientific_journal-766	432	15	four	four	NUM
american_scientific_journal-766	432	16	allost	allost	NOUN
american_scientific_journal-766	432	17	...	...	PUNCT
american_scientific_journal-766	433	1	2.2.5.1	2.2.5.1	X
american_scientific_journal-766	433	2	.	.	PUNCT
american_scientific_journal-766	433	3	efficacy	efficacy	NOUN
american_scientific_journal-766	433	4	and	and	CCONJ
american_scientific_journal-766	433	5	safety	safety	NOUN
american_scientific_journal-766	433	6	;	;	PUNCT
american_scientific_journal-766	433	7	following	follow	VERB
american_scientific_journal-766	433	8	on	on	ADP
american_scientific_journal-766	433	9	from	from	ADP
american_scientific_journal-766	433	10	proton	proton	NOUN
american_scientific_journal-766	433	11	and	and	CCONJ
american_scientific_journal-766	433	12	atomic	atomic	NOUN
american_scientific_journal-766	433	13	,	,	PUNCT
american_scientific_journal-766	433	14	the	the	DET
american_scientific_journal-766	433	15	electron	electron	NOUN
american_scientific_journal-766	433	16	study	study	NOUN
american_scientific_journal-766	433	17	evaluated	evaluate	VERB
american_scientific_journal-766	433	18	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	433	19	in	in	ADP
american_scientific_journal-766	433	20	interferon	interferon	ADJ
american_scientific_journal-766	433	21	-	-	PUNCT
american_scientific_journal-766	433	22	sparing	spare	VERB
american_scientific_journal-766	433	23	and	and	CCONJ
american_scientific_journal-766	433	24	interferon	interferon	ADJ
american_scientific_journal-766	433	25	-	-	PUNCT
american_scientific_journal-766	433	26	free	free	ADJ
american_scientific_journal-766	433	27	regimens	regimen	NOUN
american_scientific_journal-766	433	28	for	for	ADP
american_scientific_journal-766	433	29	the	the	DET
american_scientific_journal-766	433	30	treatment	treatment	NOUN
american_scientific_journal-766	433	31	of	of	ADP
american_scientific_journal-766	433	32	hcv	hcv	ADJ
american_scientific_journal-766	433	33	infection	infection	NOUN
american_scientific_journal-766	433	34	in	in	ADP
american_scientific_journal-766	433	35	noncirrhotic	noncirrhotic	ADJ
american_scientific_journal-766	433	36	patients	patient	NOUN
american_scientific_journal-766	433	37	.	.	PUNCT
american_scientific_journal-766	434	1	the	the	DET
american_scientific_journal-766	434	2	electron	electron	NOUN
american_scientific_journal-766	434	3	trial	trial	NOUN
american_scientific_journal-766	434	4	was	be	AUX
american_scientific_journal-766	434	5	the	the	DET
american_scientific_journal-766	434	6	first	first	ADJ
american_scientific_journal-766	434	7	phase	phase	NOUN
american_scientific_journal-766	434	8	ii	ii	PROPN
american_scientific_journal-766	434	9	study	study	NOUN
american_scientific_journal-766	434	10	in	in	ADP
american_scientific_journal-766	434	11	treatment	treatment	NOUN
american_scientific_journal-766	434	12	-	-	PUNCT
american_scientific_journal-766	434	13	n	n	CCONJ
american_scientific_journal-766	434	14	...	...	PUNCT
american_scientific_journal-766	434	15	neutrino	neutrino	NOUN
american_scientific_journal-766	434	16	was	be	AUX
american_scientific_journal-766	434	17	the	the	DET
american_scientific_journal-766	434	18	first	first	ADJ
american_scientific_journal-766	434	19	sof	sof	NOUN
american_scientific_journal-766	434	20	phase	phase	NOUN
american_scientific_journal-766	434	21	iii	iii	NUM
american_scientific_journal-766	434	22	trial	trial	NOUN
american_scientific_journal-766	434	23	in	in	ADP
american_scientific_journal-766	434	24	naïve	naïve	ADJ
american_scientific_journal-766	434	25	patients	patient	NOUN
american_scientific_journal-766	434	26	with	with	ADP
american_scientific_journal-766	434	27	the	the	DET
american_scientific_journal-766	434	28	aim	aim	NOUN
american_scientific_journal-766	434	29	to	to	PART
american_scientific_journal-766	434	30	evaluate	evaluate	VERB
american_scientific_journal-766	434	31	the	the	DET
american_scientific_journal-766	434	32	safety	safety	NOUN
american_scientific_journal-766	434	33	and	and	CCONJ
american_scientific_journal-766	434	34	efficacy	efficacy	NOUN
american_scientific_journal-766	434	35	of	of	ADP
american_scientific_journal-766	434	36	the	the	DET
american_scientific_journal-766	434	37	combination	combination	NOUN
american_scientific_journal-766	434	38	regimen	regimen	NOUN
american_scientific_journal-766	434	39	sof	sof	VERB
american_scientific_journal-766	434	40	/	/	SYM
american_scientific_journal-766	434	41	pegifn	pegifn	NOUN
american_scientific_journal-766	434	42	/	/	SYM
american_scientific_journal-766	434	43	rbv	rbv	NOUN
american_scientific_journal-766	434	44	for	for	ADP
american_scientific_journal-766	434	45	12	12	NUM
american_scientific_journal-766	434	46	weeks	week	NOUN
american_scientific_journal-766	434	47	.	.	PUNCT
american_scientific_journal-766	435	1	the	the	DET
american_scientific_journal-766	435	2	neutrino	neutrino	NOUN
american_scientific_journal-766	435	3	trial	trial	NOUN
american_scientific_journal-766	435	4	included	include	VERB
american_scientific_journal-766	435	5	28	28	NUM
american_scientific_journal-766	435	6	chc	chc	NOUN
american_scientific_journal-766	435	7	patients	patient	NOUN
american_scientific_journal-766	435	8	with	with	ADP
american_scientific_journal-766	435	9	genotype	genotype	NOUN
american_scientific_journal-766	435	10	4	4	NUM
american_scientific_journal-766	435	11	and	and	CCONJ
american_scientific_journal-766	435	12	7	7	NUM
american_scientific_journal-766	435	13	patients	patient	NOUN
american_scientific_journal-766	435	14	with	with	ADP
american_scientific_journal-766	435	15	genot	genot	ADV
american_scientific_journal-766	435	16	...	...	PUNCT
american_scientific_journal-766	435	17	in	in	ADP
american_scientific_journal-766	435	18	a	a	DET
american_scientific_journal-766	435	19	phase	phase	NOUN
american_scientific_journal-766	435	20	iii	iii	NUM
american_scientific_journal-766	435	21	non	non	ADJ
american_scientific_journal-766	435	22	-	-	ADJ
american_scientific_journal-766	435	23	inferiority	inferiority	ADJ
american_scientific_journal-766	435	24	trial	trial	NOUN
american_scientific_journal-766	435	25	study	study	NOUN
american_scientific_journal-766	435	26	named	name	VERB
american_scientific_journal-766	435	27	fission	fission	NOUN
american_scientific_journal-766	435	28	,	,	PUNCT
american_scientific_journal-766	435	29	nearly	nearly	ADV
american_scientific_journal-766	435	30	500	500	NUM
american_scientific_journal-766	435	31	genotype	genotype	NOUN
american_scientific_journal-766	435	32	2	2	NUM
american_scientific_journal-766	435	33	or	or	CCONJ
american_scientific_journal-766	435	34	3	3	NUM
american_scientific_journal-766	435	35	naïve	naïve	ADJ
american_scientific_journal-766	435	36	chc	chc	NOUN
american_scientific_journal-766	435	37	patients	patient	NOUN
american_scientific_journal-766	435	38	were	be	AUX
american_scientific_journal-766	435	39	randomized	randomize	VERB
american_scientific_journal-766	435	40	to	to	PART
american_scientific_journal-766	435	41	receive	receive	VERB
american_scientific_journal-766	435	42	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	435	43	plus	plus	CCONJ
american_scientific_journal-766	435	44	weight	weight	NOUN
american_scientific_journal-766	435	45	-	-	PUNCT
american_scientific_journal-766	435	46	based	base	VERB
american_scientific_journal-766	435	47	rbv	rbv	NOUN
american_scientific_journal-766	435	48	for	for	ADP
american_scientific_journal-766	435	49	12	12	NUM
american_scientific_journal-766	435	50	weeks	week	NOUN
american_scientific_journal-766	435	51	(	(	PUNCT
american_scientific_journal-766	435	52	n=256	n=256	NOUN
american_scientific_journal-766	435	53	)	)	PUNCT
american_scientific_journal-766	435	54	or	or	CCONJ
american_scientific_journal-766	435	55	soc	soc	NOUN
american_scientific_journal-766	435	56	,	,	PUNCT
american_scientific_journal-766	435	57	i.e.	i.e.	X
american_scientific_journal-766	435	58	pegifn	pegifn	NOUN
american_scientific_journal-766	435	59	plus	plus	CCONJ
american_scientific_journal-766	435	60	rbv	rbv	PROPN
american_scientific_journal-766	435	61	(	(	PUNCT
american_scientific_journal-766	435	62	800	800	NUM
american_scientific_journal-766	435	63	mg	mg	NOUN
american_scientific_journal-766	435	64	daily	daily	ADV
american_scientific_journal-766	435	65	)	)	PUNCT
american_scientific_journal-766	435	66	for	for	ADP
american_scientific_journal-766	435	67	24	24	NUM
american_scientific_journal-766	435	68	weeks	week	NOUN
american_scientific_journal-766	435	69	(	(	PUNCT
american_scientific_journal-766	435	70	n=243	n=243	NUM
american_scientific_journal-766	435	71	)	)	PUNCT
american_scientific_journal-766	435	72	.	.	PUNCT
american_scientific_journal-766	436	1	...	...	PUNCT
american_scientific_journal-766	437	1	the	the	DET
american_scientific_journal-766	437	2	efficacy	efficacy	NOUN
american_scientific_journal-766	437	3	of	of	ADP
american_scientific_journal-766	437	4	the	the	DET
american_scientific_journal-766	437	5	sof	sof	PROPN
american_scientific_journal-766	437	6	/	/	SYM
american_scientific_journal-766	437	7	rbv	rbv	NOUN
american_scientific_journal-766	437	8	ifn	ifn	NOUN
american_scientific_journal-766	437	9	-	-	PUNCT
american_scientific_journal-766	437	10	free	free	ADJ
american_scientific_journal-766	437	11	combination	combination	NOUN
american_scientific_journal-766	437	12	in	in	ADP
american_scientific_journal-766	437	13	patients	patient	NOUN
american_scientific_journal-766	437	14	with	with	ADP
american_scientific_journal-766	437	15	a	a	DET
american_scientific_journal-766	437	16	previous	previous	ADJ
american_scientific_journal-766	437	17	treatment	treatment	NOUN
american_scientific_journal-766	437	18	failure	failure	NOUN
american_scientific_journal-766	437	19	to	to	ADP
american_scientific_journal-766	437	20	pegifn	pegifn	NOUN
american_scientific_journal-766	437	21	/	/	SYM
american_scientific_journal-766	437	22	rbv	rbv	NOUN
american_scientific_journal-766	437	23	was	be	AUX
american_scientific_journal-766	437	24	investigated	investigate	VERB
american_scientific_journal-766	437	25	in	in	ADP
american_scientific_journal-766	437	26	the	the	DET
american_scientific_journal-766	437	27	fusion	fusion	NOUN
american_scientific_journal-766	437	28	trial	trial	NOUN
american_scientific_journal-766	437	29	.	.	PUNCT
american_scientific_journal-766	438	1	overall	overall	ADJ
american_scientific_journal-766	438	2	svr	svr	PROPN
american_scientific_journal-766	438	3	in	in	ADP
american_scientific_journal-766	438	4	treatment	treatment	NOUN
american_scientific_journal-766	438	5	experienced	experience	VERB
american_scientific_journal-766	438	6	patients	patient	NOUN
american_scientific_journal-766	438	7	with	with	ADP
american_scientific_journal-766	438	8	sof	sof	VERB
american_scientific_journal-766	438	9	/	/	SYM
american_scientific_journal-766	438	10	rbv	rbv	NOUN
american_scientific_journal-766	438	11	was	be	AUX
american_scientific_journal-766	438	12	significantly	significantly	ADV
american_scientific_journal-766	438	13	lower	low	ADJ
american_scientific_journal-766	438	14	in	in	ADP
american_scientific_journal-766	438	15	the	the	DET
american_scientific_journal-766	438	16	12	12	NUM
american_scientific_journal-766	438	17	-	-	PUNCT
american_scientific_journal-766	438	18	week	week	NOUN
american_scientific_journal-766	438	19	compar	compar	NOUN
american_scientific_journal-766	438	20	...	...	PUNCT
american_scientific_journal-766	438	21	in	in	ADP
american_scientific_journal-766	438	22	another	another	DET
american_scientific_journal-766	438	23	phase	phase	NOUN
american_scientific_journal-766	438	24	iii	iii	NOUN
american_scientific_journal-766	438	25	,	,	PUNCT
american_scientific_journal-766	438	26	placebo	placebo	NOUN
american_scientific_journal-766	438	27	-	-	PUNCT
american_scientific_journal-766	438	28	controlled	control	VERB
american_scientific_journal-766	438	29	trial	trial	NOUN
american_scientific_journal-766	438	30	named	name	VERB
american_scientific_journal-766	438	31	positron	positron	NOUN
american_scientific_journal-766	438	32	,	,	PUNCT
american_scientific_journal-766	438	33	278	278	NUM
american_scientific_journal-766	438	34	patients	patient	NOUN
american_scientific_journal-766	438	35	with	with	ADP
american_scientific_journal-766	438	36	chc	chc	PROPN
american_scientific_journal-766	438	37	genotype	genotype	NOUN
american_scientific_journal-766	438	38	2	2	NUM
american_scientific_journal-766	438	39	or	or	CCONJ
american_scientific_journal-766	438	40	3	3	NUM
american_scientific_journal-766	438	41	who	who	PRON
american_scientific_journal-766	438	42	were	be	AUX
american_scientific_journal-766	438	43	interferon	interferon	ADJ
american_scientific_journal-766	438	44	intolerant	intolerant	ADJ
american_scientific_journal-766	438	45	or	or	CCONJ
american_scientific_journal-766	438	46	ineligible	ineligible	ADJ
american_scientific_journal-766	438	47	or	or	CCONJ
american_scientific_journal-766	438	48	had	have	AUX
american_scientific_journal-766	438	49	refused	refuse	VERB
american_scientific_journal-766	438	50	pegifn	pegifn	NOUN
american_scientific_journal-766	438	51	therapy	therapy	NOUN
american_scientific_journal-766	438	52	were	be	AUX
american_scientific_journal-766	438	53	randomized	randomize	VERB
american_scientific_journal-766	438	54	to	to	PART
american_scientific_journal-766	438	55	receive	receive	VERB
american_scientific_journal-766	438	56	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	438	57	plus	plus	CCONJ
american_scientific_journal-766	438	58	weight	weight	NOUN
american_scientific_journal-766	438	59	-	-	PUNCT
american_scientific_journal-766	438	60	based	base	VERB
american_scientific_journal-766	438	61	rbv	rbv	NOUN
american_scientific_journal-766	438	62	(	(	PUNCT
american_scientific_journal-766	438	63	n=207	n=207	NOUN
american_scientific_journal-766	438	64	)	)	PUNCT
american_scientific_journal-766	438	65	or	or	CCONJ
american_scientific_journal-766	438	66	plac	plac	NOUN
american_scientific_journal-766	438	67	...	...	PUNCT
american_scientific_journal-766	438	68	in	in	ADP
american_scientific_journal-766	438	69	a	a	DET
american_scientific_journal-766	438	70	third	third	ADJ
american_scientific_journal-766	438	71	phase	phase	NOUN
american_scientific_journal-766	438	72	iii	iii	NOUN
american_scientific_journal-766	438	73	trial	trial	NOUN
american_scientific_journal-766	438	74	named	name	VERB
american_scientific_journal-766	438	75	valence	valence	NOUN
american_scientific_journal-766	438	76	including	include	VERB
american_scientific_journal-766	438	77	genotype	genotype	NOUN
american_scientific_journal-766	438	78	2	2	NUM
american_scientific_journal-766	438	79	and	and	CCONJ
american_scientific_journal-766	438	80	3	3	NUM
american_scientific_journal-766	438	81	naïve	naïve	ADJ
american_scientific_journal-766	438	82	chc	chc	NOUN
american_scientific_journal-766	438	83	patients	patient	NOUN
american_scientific_journal-766	438	84	,	,	PUNCT
american_scientific_journal-766	438	85	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	438	86	plus	plus	CCONJ
american_scientific_journal-766	438	87	weight	weight	NOUN
american_scientific_journal-766	438	88	-	-	PUNCT
american_scientific_journal-766	438	89	based	base	VERB
american_scientific_journal-766	438	90	rbv	rbv	NOUN
american_scientific_journal-766	438	91	was	be	AUX
american_scientific_journal-766	438	92	given	give	VERB
american_scientific_journal-766	438	93	for	for	ADP
american_scientific_journal-766	438	94	12	12	NUM
american_scientific_journal-766	438	95	weeks	week	NOUN
american_scientific_journal-766	438	96	in	in	ADP
american_scientific_journal-766	438	97	genotype	genotype	NOUN
american_scientific_journal-766	438	98	2	2	NUM
american_scientific_journal-766	438	99	(	(	PUNCT
american_scientific_journal-766	438	100	n=32	n=32	PROPN
american_scientific_journal-766	438	101	)	)	PUNCT
american_scientific_journal-766	438	102	and	and	CCONJ
american_scientific_journal-766	438	103	for	for	ADP
american_scientific_journal-766	438	104	24	24	NUM
american_scientific_journal-766	438	105	weeks	week	NOUN
american_scientific_journal-766	438	106	in	in	ADP
american_scientific_journal-766	438	107	genotype	genotype	NOUN
american_scientific_journal-766	438	108	3	3	NUM
american_scientific_journal-766	438	109	patients	patient	NOUN
american_scientific_journal-766	438	110	(	(	PUNCT
american_scientific_journal-766	438	111	n=105	n=105	PROPN
american_scientific_journal-766	438	112	)	)	PUNCT
american_scientific_journal-766	438	113	.	.	PUNCT
american_scientific_journal-766	439	1	svr	svr	PROPN
american_scientific_journal-766	439	2	was	be	AUX
american_scientific_journal-766	439	3	achieved	achieve	VERB
american_scientific_journal-766	439	4	in	in	ADP
american_scientific_journal-766	439	5	97	97	NUM
american_scientific_journal-766	439	6	%	%	NOUN
american_scientific_journal-766	439	7	of	of	ADP
american_scientific_journal-766	439	8	genotype	genotype	NOUN
american_scientific_journal-766	439	9	2	2	NUM
american_scientific_journal-766	439	10	...	...	PUNCT
american_scientific_journal-766	439	11	2.2.5.2	2.2.5.2	X
american_scientific_journal-766	439	12	.	.	NOUN
american_scientific_journal-766	439	13	sof	sof	PROPN
american_scientific_journal-766	439	14	in	in	ADP
american_scientific_journal-766	439	15	combination	combination	NOUN
american_scientific_journal-766	439	16	with	with	ADP
american_scientific_journal-766	439	17	other	other	ADJ
american_scientific_journal-766	439	18	daas	daas	NOUN
american_scientific_journal-766	439	19	overall	overall	ADV
american_scientific_journal-766	439	20	,	,	PUNCT
american_scientific_journal-766	439	21	sof	sof	PROPN
american_scientific_journal-766	439	22	appears	appear	VERB
american_scientific_journal-766	439	23	to	to	PART
american_scientific_journal-766	439	24	be	be	AUX
american_scientific_journal-766	439	25	an	an	DET
american_scientific_journal-766	439	26	attractive	attractive	ADJ
american_scientific_journal-766	439	27	choice	choice	NOUN
american_scientific_journal-766	439	28	to	to	PART
american_scientific_journal-766	439	29	serve	serve	VERB
american_scientific_journal-766	439	30	as	as	ADP
american_scientific_journal-766	439	31	a	a	DET
american_scientific_journal-766	439	32	backbone	backbone	NOUN
american_scientific_journal-766	439	33	for	for	ADP
american_scientific_journal-766	439	34	future	future	ADJ
american_scientific_journal-766	439	35	daa	daa	NOUN
american_scientific_journal-766	439	36	combinations	combination	NOUN
american_scientific_journal-766	439	37	.	.	PUNCT
american_scientific_journal-766	440	1	the	the	DET
american_scientific_journal-766	440	2	possibility	possibility	NOUN
american_scientific_journal-766	440	3	of	of	ADP
american_scientific_journal-766	440	4	developing	develop	VERB
american_scientific_journal-766	440	5	an	an	DET
american_scientific_journal-766	440	6	ifn	ifn	NOUN
american_scientific_journal-766	440	7	-	-	PUNCT
american_scientific_journal-766	440	8	free	free	ADJ
american_scientific_journal-766	440	9	regimen	regiman	NOUN
american_scientific_journal-766	440	10	for	for	ADP
american_scientific_journal-766	440	11	difficult	difficult	ADJ
american_scientific_journal-766	440	12	-	-	PUNCT
american_scientific_journal-766	440	13	to	to	ADP
american_scientific_journal-766	440	14	-	-	PUNCT
american_scientific_journal-766	440	15	treat	treat	NOUN
american_scientific_journal-766	440	16	genotypes	genotype	NOUN
american_scientific_journal-766	440	17	requires	require	VERB
american_scientific_journal-766	440	18	the	the	DET
american_scientific_journal-766	440	19	combination	combination	NOUN
american_scientific_journal-766	440	20	of	of	ADP
american_scientific_journal-766	440	21	different	different	ADJ
american_scientific_journal-766	440	22	daa	daa	NOUN
american_scientific_journal-766	440	23	classes	class	NOUN
american_scientific_journal-766	440	24	to	to	PART
american_scientific_journal-766	440	25	provide	provide	VERB
american_scientific_journal-766	440	26	high	high	ADJ
american_scientific_journal-766	440	27	an	an	PRON
american_scientific_journal-766	440	28	...	...	PUNCT
american_scientific_journal-766	440	29	the	the	DET
american_scientific_journal-766	440	30	combination	combination	NOUN
american_scientific_journal-766	440	31	of	of	ADP
american_scientific_journal-766	440	32	12	12	NUM
american_scientific_journal-766	440	33	or	or	CCONJ
american_scientific_journal-766	440	34	24	24	NUM
american_scientific_journal-766	440	35	weeks	week	NOUN
american_scientific_journal-766	440	36	of	of	ADP
american_scientific_journal-766	440	37	sof	sof	PROPN
american_scientific_journal-766	440	38	plus	plus	CCONJ
american_scientific_journal-766	440	39	the	the	DET
american_scientific_journal-766	440	40	ns3	ns3	NOUN
american_scientific_journal-766	440	41	inhibitor	inhibitor	NOUN
american_scientific_journal-766	440	42	simeprevir	simeprevir	NOUN
american_scientific_journal-766	440	43	was	be	AUX
american_scientific_journal-766	440	44	evaluated	evaluate	VERB
american_scientific_journal-766	440	45	by	by	ADP
american_scientific_journal-766	440	46	the	the	DET
american_scientific_journal-766	440	47	cosmos	cosmos	PROPN
american_scientific_journal-766	440	48	phase	phase	NOUN
american_scientific_journal-766	440	49	ii	ii	PROPN
american_scientific_journal-766	440	50	study	study	NOUN
american_scientific_journal-766	440	51	,	,	PUNCT
american_scientific_journal-766	440	52	where	where	SCONJ
american_scientific_journal-766	440	53	an	an	DET
american_scientific_journal-766	440	54	overall	overall	ADJ
american_scientific_journal-766	440	55	93	93	NUM
american_scientific_journal-766	440	56	%	%	NOUN
american_scientific_journal-766	440	57	svr12	svr12	ADJ
american_scientific_journal-766	440	58	rate	rate	NOUN
american_scientific_journal-766	440	59	in	in	ADP
american_scientific_journal-766	440	60	non	non	ADJ
american_scientific_journal-766	440	61	-	-	ADJ
american_scientific_journal-766	440	62	cirrhotic	cirrhotic	ADJ
american_scientific_journal-766	440	63	hcv-1	hcv-1	X
american_scientific_journal-766	440	64	previous	previous	ADJ
american_scientific_journal-766	440	65	null	null	ADJ
american_scientific_journal-766	440	66	-	-	PUNCT
american_scientific_journal-766	440	67	responder	responder	NOUN
american_scientific_journal-766	440	68	to	to	PART
american_scientific_journal-766	440	69	pegifn	pegifn	NOUN
american_scientific_journal-766	440	70	/	/	SYM
american_scientific_journal-766	440	71	rbv	rbv	NOUN
american_scientific_journal-766	440	72	was	be	AUX
american_scientific_journal-766	440	73	obtained	obtain	VERB
american_scientific_journal-766	440	74	.	.	PUNCT
american_scientific_journal-766	441	1	interim	interim	ADJ
american_scientific_journal-766	441	2	analysis	analysis	NOUN
american_scientific_journal-766	441	3	of	of	ADP
american_scientific_journal-766	441	4	a	a	DET
american_scientific_journal-766	441	5	sec	sec	PROPN
american_scientific_journal-766	441	6	...	...	PUNCT
american_scientific_journal-766	441	7	the	the	DET
american_scientific_journal-766	441	8	two	two	NUM
american_scientific_journal-766	441	9	daa	daa	PROPN
american_scientific_journal-766	441	10	drug	drug	NOUN
american_scientific_journal-766	441	11	combinations	combination	NOUN
american_scientific_journal-766	441	12	,	,	PUNCT
american_scientific_journal-766	441	13	regardless	regardless	ADV
american_scientific_journal-766	441	14	of	of	ADP
american_scientific_journal-766	441	15	whether	whether	SCONJ
american_scientific_journal-766	441	16	rbv	rbv	NOUN
american_scientific_journal-766	441	17	was	be	AUX
american_scientific_journal-766	441	18	included	include	VERB
american_scientific_journal-766	441	19	,	,	PUNCT
american_scientific_journal-766	441	20	performed	perform	VERB
american_scientific_journal-766	441	21	impressively	impressively	ADV
american_scientific_journal-766	441	22	and	and	CCONJ
american_scientific_journal-766	441	23	led	lead	VERB
american_scientific_journal-766	441	24	to	to	PART
american_scientific_journal-766	441	25	svr	svr	VERB
american_scientific_journal-766	441	26	rates	rate	NOUN
american_scientific_journal-766	441	27	between	between	ADP
american_scientific_journal-766	441	28	79	79	NUM
american_scientific_journal-766	441	29	%	%	NOUN
american_scientific_journal-766	441	30	and	and	CCONJ
american_scientific_journal-766	441	31	100	100	NUM
american_scientific_journal-766	441	32	%	%	NOUN
american_scientific_journal-766	441	33	.	.	PUNCT
american_scientific_journal-766	442	1	recently	recently	ADV
american_scientific_journal-766	442	2	,	,	PUNCT
american_scientific_journal-766	442	3	the	the	DET
american_scientific_journal-766	442	4	fda	fda	PROPN
american_scientific_journal-766	442	5	granted	grant	VERB
american_scientific_journal-766	442	6	priority	priority	NOUN
american_scientific_journal-766	442	7	review	review	NOUN
american_scientific_journal-766	442	8	to	to	ADP
american_scientific_journal-766	442	9	gilead	gilead	PROPN
american_scientific_journal-766	442	10	’s	’s	PART
american_scientific_journal-766	442	11	new	new	ADJ
american_scientific_journal-766	442	12	drug	drug	NOUN
american_scientific_journal-766	442	13	application	application	NOUN
american_scientific_journal-766	442	14	for	for	ADP
american_scientific_journal-766	442	15	a	a	DET
american_scientific_journal-766	442	16	once	once	ADV
american_scientific_journal-766	442	17	-	-	PUNCT
american_scientific_journal-766	442	18	daily	daily	ADJ
american_scientific_journal-766	442	19	fixed	fix	VERB
american_scientific_journal-766	442	20	-	-	PUNCT
american_scientific_journal-766	442	21	dose	dose	NOUN
american_scientific_journal-766	442	22	combination	combination	NOUN
american_scientific_journal-766	442	23	...	...	PUNCT
american_scientific_journal-766	443	1	cross	cross	ADJ
american_scientific_journal-766	443	2	-	-	ADJ
american_scientific_journal-766	443	3	resistance	resistance	ADJ
american_scientific_journal-766	443	4	studies	study	NOUN
american_scientific_journal-766	443	5	have	have	AUX
american_scientific_journal-766	443	6	been	be	AUX
american_scientific_journal-766	443	7	conducted	conduct	VERB
american_scientific_journal-766	443	8	using	use	VERB
american_scientific_journal-766	443	9	panels	panel	NOUN
american_scientific_journal-766	443	10	of	of	ADP
american_scientific_journal-766	443	11	replicons	replicon	NOUN
american_scientific_journal-766	443	12	with	with	ADP
american_scientific_journal-766	443	13	mutations	mutation	NOUN
american_scientific_journal-766	443	14	in	in	ADP
american_scientific_journal-766	443	15	the	the	DET
american_scientific_journal-766	443	16	ns3/4a	ns3/4a	NUM
american_scientific_journal-766	443	17	protease	protease	NOUN
american_scientific_journal-766	443	18	,	,	PUNCT
american_scientific_journal-766	443	19	ns5a	ns5a	NOUN
american_scientific_journal-766	443	20	,	,	PUNCT
american_scientific_journal-766	443	21	and	and	CCONJ
american_scientific_journal-766	443	22	ns5b	ns5b	PROPN
american_scientific_journal-766	443	23	,	,	PUNCT
american_scientific_journal-766	443	24	which	which	PRON
american_scientific_journal-766	443	25	remained	remain	VERB
american_scientific_journal-766	443	26	susceptible	susceptible	ADJ
american_scientific_journal-766	443	27	to	to	ADP
american_scientific_journal-766	443	28	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	443	29	(	(	PUNCT
american_scientific_journal-766	443	30	except	except	SCONJ
american_scientific_journal-766	443	31	for	for	ADP
american_scientific_journal-766	443	32	hcv	hcv	NOUN
american_scientific_journal-766	443	33	type	type	NOUN
american_scientific_journal-766	443	34	1b	1b	PROPN
american_scientific_journal-766	443	35	s282	s282	PROPN
american_scientific_journal-766	443	36	t	t	PROPN
american_scientific_journal-766	443	37	)	)	PUNCT
american_scientific_journal-766	443	38	,	,	PUNCT
american_scientific_journal-766	443	39	thus	thus	ADV
american_scientific_journal-766	443	40	indicating	indicate	VERB
american_scientific_journal-766	443	41	that	that	SCONJ
american_scientific_journal-766	443	42	sofosbuvir	sofosbuvir	PROPN
american_scientific_journal-766	443	43	can	can	AUX
american_scientific_journal-766	443	44	be	be	AUX
american_scientific_journal-766	443	45	combined	combine	VERB
american_scientific_journal-766	443	46	with	with	ADP
american_scientific_journal-766	443	47	...	...	PUNCT
american_scientific_journal-766	443	48	2.2.5.6	2.2.5.6	NUM
american_scientific_journal-766	443	49	.	.	PUNCT
american_scientific_journal-766	443	50	drug	drug	NOUN
american_scientific_journal-766	443	51	interactions	interaction	NOUN
american_scientific_journal-766	443	52	3	3	NUM
american_scientific_journal-766	443	53	.	.	PUNCT
american_scientific_journal-766	443	54	conclusions	conclusion	NOUN
american_scientific_journal-766	443	55	and	and	CCONJ
american_scientific_journal-766	443	56	future	future	ADJ
american_scientific_journal-766	443	57	perspectives	perspective	NOUN
american_scientific_journal-766	443	58	acknowledgment	acknowledgment	NOUN
american_scientific_journal-766	443	59	we	we	PRON
american_scientific_journal-766	443	60	are	be	AUX
american_scientific_journal-766	443	61	grateful	grateful	ADJ
american_scientific_journal-766	443	62	to	to	ADP
american_scientific_journal-766	443	63	the	the	DET
american_scientific_journal-766	443	64	stuff	stuff	NOUN
american_scientific_journal-766	443	65	members	member	NOUN
american_scientific_journal-766	443	66	of	of	ADP
american_scientific_journal-766	443	67	zoology	zoology	NOUN
american_scientific_journal-766	443	68	departments	department	NOUN
american_scientific_journal-766	443	69	,	,	PUNCT
american_scientific_journal-766	443	70	faculty	faculty	NOUN
american_scientific_journal-766	443	71	of	of	ADP
american_scientific_journal-766	443	72	science	science	NOUN
american_scientific_journal-766	443	73	,	,	PUNCT
american_scientific_journal-766	443	74	beni	beni	ADJ
american_scientific_journal-766	443	75	suef	suef	PROPN
american_scientific_journal-766	443	76	university	university	NOUN
american_scientific_journal-766	443	77	,	,	PUNCT
american_scientific_journal-766	443	78	for	for	ADP
american_scientific_journal-766	443	79	providing	provide	VERB
american_scientific_journal-766	443	80	facilities	facility	NOUN
american_scientific_journal-766	443	81	to	to	PART
american_scientific_journal-766	443	82	finish	finish	VERB
american_scientific_journal-766	443	83	this	this	DET
american_scientific_journal-766	443	84	work	work	NOUN
american_scientific_journal-766	443	85	.	.	PUNCT
american_scientific_journal-766	444	1	compliance	compliance	NOUN
american_scientific_journal-766	444	2	with	with	ADP
american_scientific_journal-766	444	3	ethics	ethic	NOUN
american_scientific_journal-766	444	4	requirements	requirement	NOUN
american_scientific_journal-766	444	5	[	[	X
american_scientific_journal-766	444	6	7	7	X
american_scientific_journal-766	444	7	]	]	PUNCT
american_scientific_journal-766	444	8	razavi	razavi	NOUN
american_scientific_journal-766	444	9	h	h	PROPN
american_scientific_journal-766	444	10	,	,	PUNCT
american_scientific_journal-766	444	11	el	el	PROPN
american_scientific_journal-766	444	12	-	-	PUNCT
american_scientific_journal-766	444	13	khoury	khoury	PROPN
american_scientific_journal-766	444	14	ac	ac	PROPN
american_scientific_journal-766	444	15	,	,	PUNCT
american_scientific_journal-766	444	16	elbasha	elbasha	PROPN
american_scientific_journal-766	444	17	e	e	PROPN
american_scientific_journal-766	444	18	,	,	PUNCT
american_scientific_journal-766	444	19	estes	este	NOUN
american_scientific_journal-766	444	20	c	c	PROPN
american_scientific_journal-766	444	21	,	,	PUNCT
american_scientific_journal-766	444	22	pasini	pasini	PROPN
american_scientific_journal-766	444	23	k	k	PROPN
american_scientific_journal-766	444	24	,	,	PUNCT
american_scientific_journal-766	444	25	poynard	poynard	PROPN
american_scientific_journal-766	444	26	t	t	PROPN
american_scientific_journal-766	444	27	,	,	PUNCT
american_scientific_journal-766	444	28	kumar	kumar	PROPN
american_scientific_journal-766	444	29	r	r	PROPN
american_scientific_journal-766	444	30	,	,	PUNCT
american_scientific_journal-766	444	31	(	(	PUNCT
american_scientific_journal-766	444	32	2013),chronic	2013),chronic	NUM
american_scientific_journal-766	444	33	hepatitis	hepatitis	NOUN
american_scientific_journal-766	444	34	c	c	PROPN
american_scientific_journal-766	444	35	virus	virus	NOUN
american_scientific_journal-766	444	36	(	(	PUNCT
american_scientific_journal-766	444	37	hcv	hcv	NOUN
american_scientific_journal-766	444	38	)	)	PUNCT
american_scientific_journal-766	444	39	disease	disease	NOUN
american_scientific_journal-766	444	40	burden	burden	NOUN
american_scientific_journal-766	444	41	and	and	CCONJ
american_scientific_journal-766	444	42	cost	cost	NOUN
american_scientific_journal-766	444	43	in	in	ADP
american_scientific_journal-766	444	44	the	the	DET
american_scientific_journal-766	444	45	united	united	PROPN
american_scientific_journal-766	444	46	states	states	PROPN
american_scientific_journal-766	444	47	,	,	PUNCT
american_scientific_journal-766	444	48	hepatology	hepatology	NOUN
american_scientific_journal-766	444	49	,	,	PUNCT
american_scientific_journal-766	444	50	57(6	57(6	NUM
american_scientific_journal-766	444	51	)	)	PUNCT
american_scientific_journal-766	444	52	,	,	PUNCT
american_scientific_journal-766	444	53	2164–70	2164–70	NUM
american_scientific_journal-766	445	1	[	[	X
american_scientific_journal-766	445	2	30	30	NUM
american_scientific_journal-766	445	3	]	]	X
american_scientific_journal-766	445	4	hunyady	hunyady	PROPN
american_scientific_journal-766	445	5	b	b	PROPN
american_scientific_journal-766	445	6	,	,	PUNCT
american_scientific_journal-766	445	7	kovács	kovács	PROPN
american_scientific_journal-766	445	8	b	b	PROPN
american_scientific_journal-766	445	9	,	,	PUNCT
american_scientific_journal-766	445	10	battyáni	battyáni	PROPN
american_scientific_journal-766	445	11	z	z	PROPN
american_scientific_journal-766	445	12	,	,	PUNCT
american_scientific_journal-766	445	13	(	(	PUNCT
american_scientific_journal-766	445	14	2011	2011	NUM
american_scientific_journal-766	445	15	)	)	PUNCT
american_scientific_journal-766	445	16	,	,	PUNCT
american_scientific_journal-766	445	17	side	side	NOUN
american_scientific_journal-766	445	18	-	-	PUNCT
american_scientific_journal-766	445	19	effects	effect	NOUN
american_scientific_journal-766	445	20	of	of	ADP
american_scientific_journal-766	445	21	pegylated	pegylated	ADJ
american_scientific_journal-766	445	22	interferon	interferon	NOUN
american_scientific_journal-766	445	23	plus	plus	CCONJ
american_scientific_journal-766	445	24	ribavirin	ribavirin	NOUN
american_scientific_journal-766	445	25	therapy	therapy	NOUN
american_scientific_journal-766	445	26	with	with	ADP
american_scientific_journal-766	445	27	or	or	CCONJ
american_scientific_journal-766	445	28	without	without	ADP
american_scientific_journal-766	445	29	protease	protease	NOUN
american_scientific_journal-766	445	30	inhibitor	inhibitor	NOUN
american_scientific_journal-766	445	31	direct	direct	ADJ
american_scientific_journal-766	445	32	acting	act	VERB
american_scientific_journal-766	445	33	antiviral	antiviral	ADJ
american_scientific_journal-766	445	34	agents	agent	NOUN
american_scientific_journal-766	445	35	during	during	ADP
american_scientific_journal-766	445	36	treatment	treatment	NOUN
american_scientific_journal-766	445	37	of	of	ADP
american_scientific_journal-766	445	38	chronic	chronic	ADJ
american_scientific_journal-766	445	39	hepatitis	hepatitis	PROPN
american_scientific_journal-766	445	40	c	c	PROPN
american_scientific_journal-766	445	41	virus	virus	NOUN
american_scientific_journal-766	445	42	infection	infection	NOUN
american_scientific_journal-766	445	43	,	,	PUNCT
american_scientific_journal-766	445	44	orv	orv	PROPN
american_scientific_journal-766	445	45	hetil	hetil	PROPN
american_scientific_journal-766	445	46	,	,	PUNCT
american_scientific_journal-766	445	47	152(50),1997-	152(50),1997-	PROPN
american_scientific_journal-766	445	48	�	�	PROPN
american_scientific_journal-766	446	1	[	[	X
american_scientific_journal-766	446	2	69	69	NUM
american_scientific_journal-766	446	3	]	]	PUNCT
american_scientific_journal-766	446	4	cholongitas	cholongitas	NOUN
american_scientific_journal-766	446	5	e	e	NOUN
american_scientific_journal-766	446	6	,	,	PUNCT
american_scientific_journal-766	446	7	papatheodoridis	papatheodoridis	PROPN
american_scientific_journal-766	446	8	gv,(2014	gv,(2014	NOUN
american_scientific_journal-766	446	9	)	)	PUNCT
american_scientific_journal-766	446	10	,	,	PUNCT
american_scientific_journal-766	446	11	sofosbuvir	sofosbuvir	VERB
american_scientific_journal-766	446	12	:	:	PUNCT
american_scientific_journal-766	446	13	a	a	DET
american_scientific_journal-766	446	14	novel	novel	ADJ
american_scientific_journal-766	446	15	oral	oral	ADJ
american_scientific_journal-766	446	16	agent	agent	NOUN
american_scientific_journal-766	446	17	for	for	ADP
american_scientific_journal-766	446	18	chronic	chronic	ADJ
american_scientific_journal-766	446	19	hepatitis	hepatitis	NOUN
american_scientific_journal-766	446	20	c	c	NOUN
american_scientific_journal-766	446	21	,	,	PUNCT
american_scientific_journal-766	446	22	ann	ann	PROPN
american_scientific_journal-766	446	23	gastroenterol	gastroenterol	PROPN
american_scientific_journal-766	446	24	,	,	PUNCT
american_scientific_journal-766	446	25	27(4	27(4	PROPN
american_scientific_journal-766	446	26	)	)	PUNCT
american_scientific_journal-766	446	27	,	,	PUNCT
american_scientific_journal-766	446	28	331–337	331–337	NUM
american_scientific_journal-766	446	29	.	.	PUNCT