id	sid	tid	token	lemma	pos
amwa-432	1	1	v40	v40	NOUN
amwa-432	1	2	n3	n3	PROPN
amwa-432	1	3	/	/	SYM
amwa-432	1	4	2025	2025	NUM
amwa-432	1	5	©	©	PROPN
amwa-432	1	6	2025	2025	NUM
amwa-432	1	7	american	american	ADJ
amwa-432	1	8	medical	medical	PROPN
amwa-432	1	9	writers	writers	PROPN
amwa-432	1	10	association	association	PROPN
amwa-432	1	11	.	.	PUNCT
amwa-432	2	1	all	all	DET
amwa-432	2	2	rights	right	NOUN
amwa-432	2	3	reserved	reserve	VERB
amwa-432	2	4	.	.	PUNCT
amwa-432	3	1	issn	issn	PROPN
amwa-432	3	2	2163	2163	NUM
amwa-432	3	3	-	-	SYM
amwa-432	3	4	5315	5315	NUM
amwa-432	3	5	amwajournal.org	amwajournal.org	X
amwa-432	3	6	35	35	NUM
amwa-432	3	7	abstract	abstract	NOUN
amwa-432	3	8	over	over	ADP
amwa-432	3	9	800	800	NUM
amwa-432	3	10	million	million	NUM
amwa-432	3	11	people	people	NOUN
amwa-432	3	12	worldwide	worldwide	ADV
amwa-432	3	13	meet	meet	VERB
amwa-432	3	14	the	the	DET
amwa-432	3	15	criteria	criterion	NOUN
amwa-432	3	16	for	for	ADP
amwa-432	3	17	obesity	obesity	NOUN
amwa-432	3	18	,	,	PUNCT
amwa-432	3	19	highlighting	highlight	VERB
amwa-432	3	20	the	the	DET
amwa-432	3	21	need	need	NOUN
amwa-432	3	22	for	for	ADP
amwa-432	3	23	safe	safe	ADJ
amwa-432	3	24	and	and	CCONJ
amwa-432	3	25	effective	effective	ADJ
amwa-432	3	26	treatments	treatment	NOUN
amwa-432	3	27	.	.	PUNCT
amwa-432	4	1	recent	recent	ADJ
amwa-432	4	2	advances	advance	NOUN
amwa-432	4	3	reshaped	reshape	VERB
amwa-432	4	4	the	the	DET
amwa-432	4	5	paradigm	paradigm	NOUN
amwa-432	4	6	of	of	ADP
amwa-432	4	7	adipose	adipose	NOUN
amwa-432	4	8	as	as	ADP
amwa-432	4	9	an	an	DET
amwa-432	4	10	organ	organ	NOUN
amwa-432	4	11	that	that	PRON
amwa-432	4	12	regulates	regulate	VERB
amwa-432	4	13	hunger	hunger	NOUN
amwa-432	4	14	,	,	PUNCT
amwa-432	4	15	satiety	satiety	NOUN
amwa-432	4	16	,	,	PUNCT
amwa-432	4	17	insulin	insulin	NOUN
amwa-432	4	18	sensitivity	sensitivity	NOUN
amwa-432	4	19	,	,	PUNCT
amwa-432	4	20	and	and	CCONJ
amwa-432	4	21	inflammation	inflammation	NOUN
amwa-432	4	22	.	.	PUNCT
amwa-432	5	1	clinical	clinical	ADJ
amwa-432	5	2	obesity	obesity	NOUN
amwa-432	5	3	is	be	AUX
amwa-432	5	4	a	a	DET
amwa-432	5	5	chronic	chronic	ADJ
amwa-432	5	6	condition	condition	NOUN
amwa-432	5	7	linked	link	VERB
amwa-432	5	8	to	to	ADP
amwa-432	5	9	excess	excess	ADJ
amwa-432	5	10	visceral	visceral	ADJ
amwa-432	5	11	adipose	adipose	NOUN
amwa-432	5	12	in	in	ADP
amwa-432	5	13	which	which	PRON
amwa-432	5	14	the	the	DET
amwa-432	5	15	health	health	NOUN
amwa-432	5	16	risk	risk	NOUN
amwa-432	5	17	has	have	AUX
amwa-432	5	18	already	already	ADV
amwa-432	5	19	manifested	manifest	VERB
amwa-432	5	20	.	.	PUNCT
amwa-432	6	1	this	this	DET
amwa-432	6	2	definition	definition	NOUN
amwa-432	6	3	reflects	reflect	VERB
amwa-432	6	4	our	our	PRON
amwa-432	6	5	understanding	understanding	NOUN
amwa-432	6	6	of	of	ADP
amwa-432	6	7	obesity	obesity	NOUN
amwa-432	6	8	,	,	PUNCT
amwa-432	6	9	rather	rather	ADV
amwa-432	6	10	than	than	ADP
amwa-432	6	11	relating	relate	VERB
amwa-432	6	12	it	it	PRON
amwa-432	6	13	to	to	ADP
amwa-432	6	14	body	body	NOUN
amwa-432	6	15	size	size	NOUN
amwa-432	6	16	,	,	PUNCT
amwa-432	6	17	weight	weight	NOUN
amwa-432	6	18	-	-	PUNCT
amwa-432	6	19	based	base	VERB
amwa-432	6	20	conditions	condition	NOUN
amwa-432	6	21	,	,	PUNCT
amwa-432	6	22	or	or	CCONJ
amwa-432	6	23	elevated	elevated	ADJ
amwa-432	6	24	body	body	NOUN
amwa-432	6	25	mass	mass	NOUN
amwa-432	6	26	index	index	NOUN
amwa-432	6	27	.	.	PUNCT
amwa-432	7	1	clinical	clinical	ADJ
amwa-432	7	2	guidelines	guideline	NOUN
amwa-432	7	3	recommend	recommend	VERB
amwa-432	7	4	pharmacotherapy	pharmacotherapy	NOUN
amwa-432	7	5	for	for	ADP
amwa-432	7	6	children	child	NOUN
amwa-432	7	7	and	and	CCONJ
amwa-432	7	8	adults	adult	NOUN
amwa-432	7	9	meeting	meet	VERB
amwa-432	7	10	the	the	DET
amwa-432	7	11	criteria	criterion	NOUN
amwa-432	7	12	for	for	ADP
amwa-432	7	13	obesity	obesity	NOUN
amwa-432	7	14	.	.	PUNCT
amwa-432	8	1	because	because	SCONJ
amwa-432	8	2	few	few	ADJ
amwa-432	8	3	independent	independent	ADJ
amwa-432	8	4	diverse	diverse	ADJ
amwa-432	8	5	trials	trial	NOUN
amwa-432	8	6	compare	compare	VERB
amwa-432	8	7	obesity	obesity	NOUN
amwa-432	8	8	drugs	drug	NOUN
amwa-432	8	9	,	,	PUNCT
amwa-432	8	10	doctors	doctor	NOUN
amwa-432	8	11	must	must	AUX
amwa-432	8	12	resort	resort	VERB
amwa-432	8	13	to	to	ADP
amwa-432	8	14	trial	trial	NOUN
amwa-432	8	15	-	-	PUNCT
amwa-432	8	16	and	and	CCONJ
amwa-432	8	17	-	-	PUNCT
amwa-432	8	18	error	error	NOUN
amwa-432	8	19	to	to	PART
amwa-432	8	20	predict	predict	VERB
amwa-432	8	21	usefulness	usefulness	NOUN
amwa-432	8	22	.	.	PUNCT
amwa-432	9	1	and	and	CCONJ
amwa-432	9	2	the	the	DET
amwa-432	9	3	lack	lack	NOUN
amwa-432	9	4	of	of	ADP
amwa-432	9	5	diversity	diversity	NOUN
amwa-432	9	6	may	may	AUX
amwa-432	9	7	impact	impact	VERB
amwa-432	9	8	drug	drug	NOUN
amwa-432	9	9	safety	safety	NOUN
amwa-432	9	10	for	for	ADP
amwa-432	9	11	at	at	ADP
amwa-432	9	12	-	-	PUNCT
amwa-432	9	13	risk	risk	NOUN
amwa-432	9	14	populations	population	NOUN
amwa-432	9	15	.	.	PUNCT
amwa-432	10	1	for	for	ADP
amwa-432	10	2	example	example	NOUN
amwa-432	10	3	,	,	PUNCT
amwa-432	10	4	black	black	ADJ
amwa-432	10	5	and	and	CCONJ
amwa-432	10	6	hispanic	hispanic	ADJ
amwa-432	10	7	adults	adult	NOUN
amwa-432	10	8	are	be	AUX
amwa-432	10	9	at	at	ADP
amwa-432	10	10	the	the	DET
amwa-432	10	11	highest	high	ADJ
amwa-432	10	12	risk	risk	NOUN
amwa-432	10	13	for	for	ADP
amwa-432	10	14	obesity	obesity	NOUN
amwa-432	10	15	,	,	PUNCT
amwa-432	10	16	but	but	CCONJ
amwa-432	10	17	few	few	ADJ
amwa-432	10	18	participated	participate	VERB
amwa-432	10	19	in	in	ADP
amwa-432	10	20	drug	drug	NOUN
amwa-432	10	21	trials	trial	NOUN
amwa-432	10	22	.	.	PUNCT
amwa-432	11	1	the	the	DET
amwa-432	11	2	discovery	discovery	NOUN
amwa-432	11	3	of	of	ADP
amwa-432	11	4	incretins	incretin	NOUN
amwa-432	11	5	led	lead	VERB
amwa-432	11	6	to	to	ADP
amwa-432	11	7	incretin	incretin	NOUN
amwa-432	11	8	-	-	PUNCT
amwa-432	11	9	based	base	VERB
amwa-432	11	10	hormone	hormone	NOUN
amwa-432	11	11	drugs	drug	NOUN
amwa-432	11	12	that	that	PRON
amwa-432	11	13	bind	bind	VERB
amwa-432	11	14	glucagon	glucagon	NOUN
amwa-432	11	15	-	-	PUNCT
amwa-432	11	16	like	like	ADJ
amwa-432	11	17	peptide-1	peptide-1	NOUN
amwa-432	11	18	or	or	CCONJ
amwa-432	11	19	glucose	glucose	NOUN
amwa-432	11	20	-	-	PUNCT
amwa-432	11	21	dependent	dependent	ADJ
amwa-432	11	22	insulinotropic	insulinotropic	NOUN
amwa-432	11	23	polypeptide	polypeptide	ADJ
amwa-432	11	24	receptors	receptor	NOUN
amwa-432	11	25	.	.	PUNCT
amwa-432	12	1	the	the	DET
amwa-432	12	2	media	media	NOUN
amwa-432	12	3	attention	attention	NOUN
amwa-432	12	4	around	around	ADP
amwa-432	12	5	these	these	DET
amwa-432	12	6	repurposed	repurpose	VERB
amwa-432	12	7	type	type	NOUN
amwa-432	12	8	2	2	NUM
amwa-432	12	9	diabetes	diabetes	NOUN
amwa-432	12	10	drugs	drug	NOUN
amwa-432	12	11	brings	bring	VERB
amwa-432	12	12	hope	hope	NOUN
amwa-432	12	13	for	for	ADP
amwa-432	12	14	obesity	obesity	NOUN
amwa-432	12	15	treatment	treatment	NOUN
amwa-432	12	16	in	in	ADP
amwa-432	12	17	clinical	clinical	ADJ
amwa-432	12	18	practice	practice	NOUN
amwa-432	12	19	.	.	PUNCT
amwa-432	13	1	manufacturers	manufacturer	NOUN
amwa-432	13	2	market	market	VERB
amwa-432	13	3	incretin	incretin	NOUN
amwa-432	13	4	drugs	drug	NOUN
amwa-432	13	5	as	as	ADP
amwa-432	13	6	a	a	DET
amwa-432	13	7	panacea	panacea	NOUN
amwa-432	13	8	for	for	ADP
amwa-432	13	9	neurological	neurological	ADJ
amwa-432	13	10	,	,	PUNCT
amwa-432	13	11	metabolic	metabolic	NOUN
amwa-432	13	12	,	,	PUNCT
amwa-432	13	13	and	and	CCONJ
amwa-432	13	14	cardiovascular	cardiovascular	ADJ
amwa-432	13	15	conditions	condition	NOUN
amwa-432	13	16	.	.	PUNCT
amwa-432	14	1	filling	fill	VERB
amwa-432	14	2	a	a	DET
amwa-432	14	3	unique	unique	ADJ
amwa-432	14	4	therapeutic	therapeutic	ADJ
amwa-432	14	5	gap	gap	NOUN
amwa-432	14	6	between	between	ADP
amwa-432	14	7	lifestyle	lifestyle	NOUN
amwa-432	14	8	modification	modification	NOUN
amwa-432	14	9	and	and	CCONJ
amwa-432	14	10	bariatric	bariatric	ADJ
amwa-432	14	11	surgery	surgery	NOUN
amwa-432	14	12	,	,	PUNCT
amwa-432	14	13	incretin	incretin	NOUN
amwa-432	14	14	drugs	drug	NOUN
amwa-432	14	15	may	may	AUX
amwa-432	14	16	help	help	VERB
amwa-432	14	17	some	some	DET
amwa-432	14	18	people	people	NOUN
amwa-432	14	19	.	.	PUNCT
amwa-432	15	1	yet	yet	ADV
amwa-432	15	2	,	,	PUNCT
amwa-432	15	3	with	with	ADP
amwa-432	15	4	any	any	DET
amwa-432	15	5	medication	medication	NOUN
amwa-432	15	6	,	,	PUNCT
amwa-432	15	7	balancing	balance	VERB
amwa-432	15	8	benefits	benefit	NOUN
amwa-432	15	9	and	and	CCONJ
amwa-432	15	10	risks	risk	NOUN
amwa-432	15	11	optimizes	optimize	VERB
amwa-432	15	12	health	health	NOUN
amwa-432	15	13	.	.	PUNCT
amwa-432	16	1	thus	thus	ADV
amwa-432	16	2	,	,	PUNCT
amwa-432	16	3	long	long	ADJ
amwa-432	16	4	-	-	PUNCT
amwa-432	16	5	term	term	NOUN
amwa-432	16	6	safety	safety	NOUN
amwa-432	16	7	studies	study	NOUN
amwa-432	16	8	comparing	compare	VERB
amwa-432	16	9	incretin	incretin	ADJ
amwa-432	16	10	drugs	drug	NOUN
amwa-432	16	11	in	in	ADP
amwa-432	16	12	a	a	DET
amwa-432	16	13	diverse	diverse	ADJ
amwa-432	16	14	population	population	NOUN
amwa-432	16	15	are	be	AUX
amwa-432	16	16	needed	need	VERB
amwa-432	16	17	for	for	ADP
amwa-432	16	18	the	the	DET
amwa-432	16	19	development	development	NOUN
amwa-432	16	20	of	of	ADP
amwa-432	16	21	safe	safe	ADJ
amwa-432	16	22	and	and	CCONJ
amwa-432	16	23	effective	effective	ADJ
amwa-432	16	24	treatments	treatment	NOUN
amwa-432	16	25	.	.	PUNCT
amwa-432	17	1	understanding	understand	VERB
amwa-432	17	2	the	the	DET
amwa-432	17	3	health	health	NOUN
amwa-432	17	4	benefits	benefit	NOUN
amwa-432	17	5	after	after	ADP
amwa-432	17	6	bariatric	bariatric	ADJ
amwa-432	17	7	surgery	surgery	NOUN
amwa-432	17	8	,	,	PUNCT
amwa-432	17	9	drug	drug	NOUN
amwa-432	17	10	therapy	therapy	NOUN
amwa-432	17	11	,	,	PUNCT
amwa-432	17	12	and	and	CCONJ
amwa-432	17	13	combination	combination	NOUN
amwa-432	17	14	therapy	therapy	NOUN
amwa-432	17	15	may	may	AUX
amwa-432	17	16	help	help	VERB
amwa-432	17	17	guide	guide	VERB
amwa-432	17	18	future	future	ADJ
amwa-432	17	19	clinical	clinical	ADJ
amwa-432	17	20	practice	practice	NOUN
amwa-432	17	21	.	.	PUNCT
amwa-432	18	1	a	a	DET
amwa-432	18	2	magical	magical	ADJ
amwa-432	18	3	remedy	remedy	NOUN
amwa-432	18	4	to	to	PART
amwa-432	18	5	control	control	VERB
amwa-432	18	6	human	human	ADJ
amwa-432	18	7	metabolism	metabolism	NOUN
amwa-432	18	8	has	have	AUX
amwa-432	18	9	evaded	evade	VERB
amwa-432	18	10	scientists	scientist	NOUN
amwa-432	18	11	for	for	ADP
amwa-432	18	12	over	over	ADP
amwa-432	18	13	130	130	NUM
amwa-432	18	14	years	year	NOUN
amwa-432	18	15	.	.	PUNCT
amwa-432	19	1	since	since	SCONJ
amwa-432	19	2	the	the	DET
amwa-432	19	3	nineteenth	nineteenth	ADJ
amwa-432	19	4	century	century	NOUN
amwa-432	19	5	,	,	PUNCT
amwa-432	19	6	manufacturers	manufacturer	NOUN
amwa-432	19	7	have	have	AUX
amwa-432	19	8	sold	sell	VERB
amwa-432	19	9	various	various	ADJ
amwa-432	19	10	weight	weight	NOUN
amwa-432	19	11	-	-	PUNCT
amwa-432	19	12	lowering	lower	VERB
amwa-432	19	13	tonics	tonic	NOUN
amwa-432	19	14	,	,	PUNCT
amwa-432	19	15	banned	ban	VERB
amwa-432	19	16	from	from	ADP
amwa-432	19	17	sale	sale	NOUN
amwa-432	19	18	because	because	SCONJ
amwa-432	19	19	of	of	ADP
amwa-432	19	20	safety	safety	NOUN
amwa-432	19	21	issues	issue	NOUN
amwa-432	19	22	.	.	PUNCT
amwa-432	20	1	as	as	SCONJ
amwa-432	20	2	the	the	DET
amwa-432	20	3	philosopher	philosopher	NOUN
amwa-432	20	4	santayana	santayana	PROPN
amwa-432	20	5	said	say	VERB
amwa-432	20	6	,	,	PUNCT
amwa-432	20	7	“	"	PUNCT
amwa-432	20	8	those	those	PRON
amwa-432	20	9	who	who	PRON
amwa-432	20	10	can	can	AUX
amwa-432	20	11	not	not	PART
amwa-432	20	12	remember	remember	VERB
amwa-432	20	13	the	the	DET
amwa-432	20	14	past	past	NOUN
amwa-432	20	15	are	be	AUX
amwa-432	20	16	condemned	condemn	VERB
amwa-432	20	17	to	to	PART
amwa-432	20	18	repeat	repeat	VERB
amwa-432	20	19	it	it	PRON
amwa-432	20	20	.	.	PUNCT
amwa-432	20	21	”	"	PUNCT
amwa-432	21	1	and	and	CCONJ
amwa-432	21	2	predictably	predictably	ADV
amwa-432	21	3	,	,	PUNCT
amwa-432	21	4	without	without	ADP
amwa-432	21	5	understanding	understand	VERB
amwa-432	21	6	the	the	DET
amwa-432	21	7	underlying	underlie	VERB
amwa-432	21	8	cause	cause	NOUN
amwa-432	21	9	for	for	ADP
amwa-432	21	10	adipose	adipose	ADJ
amwa-432	21	11	dysfunction	dysfunction	NOUN
amwa-432	21	12	or	or	CCONJ
amwa-432	21	13	correcting	correct	VERB
amwa-432	21	14	past	past	ADJ
amwa-432	21	15	clinical	clinical	ADJ
amwa-432	21	16	trial	trial	NOUN
amwa-432	21	17	design	design	NOUN
amwa-432	21	18	flaws	flaw	NOUN
amwa-432	21	19	,	,	PUNCT
amwa-432	21	20	manufacturers	manufacturer	NOUN
amwa-432	21	21	continue	continue	VERB
amwa-432	21	22	to	to	PART
amwa-432	21	23	develop	develop	VERB
amwa-432	21	24	risky	risky	ADJ
amwa-432	21	25	treatments	treatment	NOUN
amwa-432	21	26	for	for	ADP
amwa-432	21	27	obesity	obesity	NOUN
amwa-432	21	28	—	—	PUNCT
amwa-432	21	29	a	a	DET
amwa-432	21	30	controversial	controversial	ADJ
amwa-432	21	31	word	word	NOUN
amwa-432	21	32	defined	define	VERB
amwa-432	21	33	by	by	ADP
amwa-432	21	34	the	the	DET
amwa-432	21	35	centers	center	NOUN
amwa-432	21	36	for	for	ADP
amwa-432	21	37	disease	disease	NOUN
amwa-432	21	38	control	control	NOUN
amwa-432	21	39	and	and	CCONJ
amwa-432	21	40	prevention	prevention	NOUN
amwa-432	21	41	(	(	PUNCT
amwa-432	21	42	cdc	cdc	PROPN
amwa-432	21	43	)	)	PUNCT
amwa-432	21	44	as	as	ADP
amwa-432	21	45	a	a	DET
amwa-432	21	46	body	body	NOUN
amwa-432	21	47	mass	mass	NOUN
amwa-432	21	48	index	index	NOUN
amwa-432	21	49	(	(	PUNCT
amwa-432	21	50	bmi	bmi	PROPN
amwa-432	21	51	)	)	PUNCT
amwa-432	21	52	of	of	ADP
amwa-432	21	53	30	30	NUM
amwa-432	21	54	or	or	CCONJ
amwa-432	21	55	more	more	ADJ
amwa-432	21	56	.	.	PUNCT
amwa-432	22	1	since	since	SCONJ
amwa-432	22	2	the	the	DET
amwa-432	22	3	us	us	PROPN
amwa-432	22	4	food	food	NOUN
amwa-432	22	5	and	and	CCONJ
amwa-432	22	6	drug	drug	PROPN
amwa-432	22	7	administration	administration	PROPN
amwa-432	22	8	(	(	PUNCT
amwa-432	22	9	fda	fda	PROPN
amwa-432	22	10	)	)	PUNCT
amwa-432	22	11	began	begin	VERB
amwa-432	22	12	regulating	regulate	VERB
amwa-432	22	13	drugs	drug	NOUN
amwa-432	22	14	in	in	ADP
amwa-432	22	15	1938	1938	NUM
amwa-432	22	16	,	,	PUNCT
amwa-432	22	17	manufacturers	manufacturer	NOUN
amwa-432	22	18	have	have	AUX
amwa-432	22	19	failed	fail	VERB
amwa-432	22	20	to	to	PART
amwa-432	22	21	produce	produce	VERB
amwa-432	22	22	safe	safe	ADJ
amwa-432	22	23	and	and	CCONJ
amwa-432	22	24	effective	effective	ADJ
amwa-432	22	25	medicines	medicine	NOUN
amwa-432	22	26	to	to	PART
amwa-432	22	27	regulate	regulate	VERB
amwa-432	22	28	metabolism.1	metabolism.1	PROPN
amwa-432	22	29	amphetamines	amphetamine	NOUN
amwa-432	22	30	and	and	CCONJ
amwa-432	22	31	sympathomimetic	sympathomimetic	ADJ
amwa-432	22	32	drugs	drug	NOUN
amwa-432	22	33	led	lead	VERB
amwa-432	22	34	to	to	ADP
amwa-432	22	35	abuse	abuse	NOUN
amwa-432	22	36	,	,	PUNCT
amwa-432	22	37	cardiac	cardiac	ADJ
amwa-432	22	38	damage	damage	NOUN
amwa-432	22	39	,	,	PUNCT
amwa-432	22	40	suicidality	suicidality	NOUN
amwa-432	22	41	,	,	PUNCT
amwa-432	22	42	cancer	cancer	NOUN
amwa-432	22	43	,	,	PUNCT
amwa-432	22	44	and	and	CCONJ
amwa-432	22	45	even	even	ADV
amwa-432	22	46	death	death	NOUN
amwa-432	22	47	(	(	PUNCT
amwa-432	22	48	figure	figure	NOUN
amwa-432	22	49	1).2	1).2	NUM
amwa-432	22	50	with	with	ADP
amwa-432	22	51	over	over	ADP
amwa-432	22	52	800	800	NUM
amwa-432	22	53	million	million	NUM
amwa-432	22	54	people	people	NOUN
amwa-432	22	55	worldwide	worldwide	ADV
amwa-432	22	56	meeting	meet	VERB
amwa-432	22	57	criteria	criterion	NOUN
amwa-432	22	58	for	for	ADP
amwa-432	22	59	obesity	obesity	NOUN
amwa-432	22	60	,	,	PUNCT
amwa-432	22	61	the	the	DET
amwa-432	22	62	need	need	NOUN
amwa-432	22	63	for	for	ADP
amwa-432	22	64	safe	safe	ADJ
amwa-432	22	65	treatments	treatment	NOUN
amwa-432	22	66	led	lead	VERB
amwa-432	22	67	to	to	ADP
amwa-432	22	68	the	the	DET
amwa-432	22	69	discovery	discovery	NOUN
amwa-432	22	70	of	of	ADP
amwa-432	22	71	incretins	incretin	NOUN
amwa-432	22	72	.	.	PUNCT
amwa-432	23	1	incretin	incretin	NOUN
amwa-432	23	2	drugs	drug	NOUN
amwa-432	23	3	include	include	VERB
amwa-432	23	4	glucagon	glucagon	NOUN
amwa-432	23	5	-	-	PUNCT
amwa-432	23	6	like	like	ADJ
amwa-432	23	7	peptide-1	peptide-1	PROPN
amwa-432	23	8	(	(	PUNCT
amwa-432	23	9	glp-1	glp-1	NOUN
amwa-432	23	10	)	)	PUNCT
amwa-432	23	11	receptor	receptor	NOUN
amwa-432	23	12	agonists	agonist	NOUN
amwa-432	23	13	(	(	PUNCT
amwa-432	23	14	ras	ras	NOUN
amwa-432	23	15	)	)	PUNCT
amwa-432	23	16	and	and	CCONJ
amwa-432	23	17	dual	dual	ADJ
amwa-432	23	18	-	-	PUNCT
amwa-432	23	19	acting	act	VERB
amwa-432	23	20	therapies	therapy	NOUN
amwa-432	23	21	that	that	PRON
amwa-432	23	22	bind	bind	VERB
amwa-432	23	23	glp-1	glp-1	ADP
amwa-432	23	24	and	and	CCONJ
amwa-432	23	25	glucose	glucose	NOUN
amwa-432	23	26	-	-	PUNCT
amwa-432	23	27	dependent	dependent	ADJ
amwa-432	23	28	insulinotropic	insulinotropic	NOUN
amwa-432	23	29	polypeptide	polypeptide	ADJ
amwa-432	23	30	(	(	PUNCT
amwa-432	23	31	gip	gip	NOUN
amwa-432	23	32	)	)	PUNCT
amwa-432	23	33	receptors	receptor	NOUN
amwa-432	23	34	.	.	PUNCT
amwa-432	24	1	recent	recent	ADJ
amwa-432	24	2	media	medium	NOUN
amwa-432	24	3	campaigns	campaign	NOUN
amwa-432	24	4	focus	focus	VERB
amwa-432	24	5	attention	attention	NOUN
amwa-432	24	6	on	on	ADP
amwa-432	24	7	these	these	DET
amwa-432	24	8	repurposed	repurpose	VERB
amwa-432	24	9	therapies	therapy	NOUN
amwa-432	24	10	,	,	PUNCT
amwa-432	24	11	bringing	bring	VERB
amwa-432	24	12	hope	hope	NOUN
amwa-432	24	13	for	for	ADP
amwa-432	24	14	clinical	clinical	ADJ
amwa-432	24	15	obesity	obesity	NOUN
amwa-432	24	16	treatment	treatment	NOUN
amwa-432	24	17	.	.	PUNCT
amwa-432	25	1	these	these	DET
amwa-432	25	2	incretin	incretin	ADJ
amwa-432	25	3	drugs	drug	NOUN
amwa-432	25	4	improve	improve	VERB
amwa-432	25	5	glycemic	glycemic	ADJ
amwa-432	25	6	control	control	NOUN
amwa-432	25	7	and	and	CCONJ
amwa-432	25	8	lower	low	ADJ
amwa-432	25	9	total	total	ADJ
amwa-432	25	10	body	body	NOUN
amwa-432	25	11	weight	weight	NOUN
amwa-432	25	12	up	up	ADP
amwa-432	25	13	to	to	PART
amwa-432	25	14	20	20	NUM
amwa-432	25	15	%	%	NOUN
amwa-432	25	16	,	,	PUNCT
amwa-432	25	17	incretin	incretin	ADJ
amwa-432	25	18	drug	drug	NOUN
amwa-432	25	19	revolution	revolution	NOUN
amwa-432	25	20	:	:	PUNCT
amwa-432	25	21	the	the	DET
amwa-432	25	22	challenges	challenge	NOUN
amwa-432	25	23	of	of	ADP
amwa-432	25	24	hope	hope	NOUN
amwa-432	25	25	alicia	alicia	PROPN
amwa-432	25	26	racelis	racelis	PROPN
amwa-432	25	27	,	,	PUNCT
amwa-432	25	28	phd	phd	NOUN
amwa-432	25	29	/	/	SYM
amwa-432	25	30	contract	contract	NOUN
amwa-432	25	31	health	health	NOUN
amwa-432	25	32	editor	editor	NOUN
amwa-432	25	33	at	at	ADP
amwa-432	25	34	webmd	webmd	PROPN
amwa-432	25	35	,	,	PUNCT
amwa-432	25	36	fayetteville	fayetteville	PROPN
amwa-432	25	37	,	,	PUNCT
amwa-432	25	38	ga	ga	PROPN
amwa-432	25	39	science	science	PROPN
amwa-432	25	40	series	series	PROPN
amwa-432	25	41	figure	figure	NOUN
amwa-432	25	42	1	1	NUM
amwa-432	25	43	.	.	PUNCT
amwa-432	25	44	timeline	timeline	NOUN
amwa-432	25	45	for	for	ADP
amwa-432	25	46	fda	fda	PROPN
amwa-432	25	47	regulation	regulation	NOUN
amwa-432	25	48	of	of	ADP
amwa-432	25	49	drugs	drug	NOUN
amwa-432	25	50	treating	treat	VERB
amwa-432	25	51	clinical	clinical	ADJ
amwa-432	25	52	obesity.2	obesity.2	NOUN
amwa-432	25	53	bold	bold	ADJ
amwa-432	25	54	italicized	italicize	VERB
amwa-432	25	55	dates	date	NOUN
amwa-432	25	56	signify	signify	VERB
amwa-432	25	57	the	the	DET
amwa-432	25	58	year	year	NOUN
amwa-432	25	59	of	of	ADP
amwa-432	25	60	removal	removal	NOUN
amwa-432	25	61	.	.	PUNCT
amwa-432	26	1	fda	fda	PROPN
amwa-432	26	2	,	,	PUNCT
amwa-432	26	3	us	us	PROPN
amwa-432	26	4	food	food	NOUN
amwa-432	26	5	and	and	CCONJ
amwa-432	26	6	drug	drug	NOUN
amwa-432	26	7	administration	administration	NOUN
amwa-432	26	8	.	.	PUNCT
amwa-432	26	9	http://www.amwajournal.org	http://www.amwajournal.org	X
amwa-432	27	1	amwajournal.org	amwajournal.org	X
amwa-432	27	2	36incretin	36incretin	NUM
amwa-432	27	3	drug	drug	NOUN
amwa-432	27	4	revolution	revolution	NOUN
amwa-432	27	5	:	:	PUNCT
amwa-432	27	6	the	the	DET
amwa-432	27	7	challenges	challenge	NOUN
amwa-432	27	8	of	of	ADP
amwa-432	27	9	hope	hope	NOUN
amwa-432	27	10	but	but	CCONJ
amwa-432	27	11	questions	question	NOUN
amwa-432	27	12	remain.3	remain.3	VERB
amwa-432	27	13	as	as	ADP
amwa-432	27	14	medical	medical	ADJ
amwa-432	27	15	writers	writer	NOUN
amwa-432	27	16	,	,	PUNCT
amwa-432	27	17	sorting	sort	VERB
amwa-432	27	18	fact	fact	NOUN
amwa-432	27	19	from	from	ADP
amwa-432	27	20	misinformation	misinformation	NOUN
amwa-432	27	21	preserves	preserve	VERB
amwa-432	27	22	data	datum	NOUN
amwa-432	27	23	integrity	integrity	NOUN
amwa-432	27	24	and	and	CCONJ
amwa-432	27	25	conveys	convey	VERB
amwa-432	27	26	related	related	ADJ
amwa-432	27	27	health	health	NOUN
amwa-432	27	28	risks	risk	NOUN
amwa-432	27	29	.	.	PUNCT
amwa-432	28	1	although	although	SCONJ
amwa-432	28	2	one	one	PRON
amwa-432	28	3	must	must	AUX
amwa-432	28	4	acknowledge	acknowledge	VERB
amwa-432	28	5	the	the	DET
amwa-432	28	6	role	role	NOUN
amwa-432	28	7	that	that	PRON
amwa-432	28	8	incretin	incretin	VERB
amwa-432	28	9	therapies	therapy	NOUN
amwa-432	28	10	play	play	VERB
amwa-432	28	11	in	in	ADP
amwa-432	28	12	balancing	balance	VERB
amwa-432	28	13	human	human	ADJ
amwa-432	28	14	metabolism	metabolism	NOUN
amwa-432	28	15	,	,	PUNCT
amwa-432	28	16	conclusions	conclusion	NOUN
amwa-432	28	17	must	must	AUX
amwa-432	28	18	be	be	AUX
amwa-432	28	19	drawn	draw	VERB
amwa-432	28	20	with	with	ADP
amwa-432	28	21	caution	caution	NOUN
amwa-432	28	22	.	.	PUNCT
amwa-432	29	1	contrary	contrary	ADJ
amwa-432	29	2	to	to	ADP
amwa-432	29	3	news	news	NOUN
amwa-432	29	4	reports	report	NOUN
amwa-432	29	5	,	,	PUNCT
amwa-432	29	6	this	this	DET
amwa-432	29	7	article	article	NOUN
amwa-432	29	8	points	point	VERB
amwa-432	29	9	out	out	ADP
amwa-432	29	10	some	some	DET
amwa-432	29	11	critical	critical	ADJ
amwa-432	29	12	issues	issue	NOUN
amwa-432	29	13	regarding	regard	VERB
amwa-432	29	14	obesity	obesity	NOUN
amwa-432	29	15	clinical	clinical	ADJ
amwa-432	29	16	trials	trial	NOUN
amwa-432	29	17	and	and	CCONJ
amwa-432	29	18	raises	raise	VERB
amwa-432	29	19	concerns	concern	NOUN
amwa-432	29	20	about	about	ADP
amwa-432	29	21	the	the	DET
amwa-432	29	22	side	side	NOUN
amwa-432	29	23	effects	effect	NOUN
amwa-432	29	24	and	and	CCONJ
amwa-432	29	25	long	long	ADJ
amwa-432	29	26	-	-	PUNCT
amwa-432	29	27	term	term	NOUN
amwa-432	29	28	safety	safety	NOUN
amwa-432	29	29	of	of	ADP
amwa-432	29	30	incretin	incretin	ADJ
amwa-432	29	31	drugs	drug	NOUN
amwa-432	29	32	.	.	PUNCT
amwa-432	30	1	defining	define	VERB
amwa-432	30	2	disease	disease	NOUN
amwa-432	30	3	:	:	PUNCT
amwa-432	30	4	clinical	clinical	ADJ
amwa-432	30	5	trials	trial	NOUN
amwa-432	30	6	for	for	ADP
amwa-432	30	7	obesity	obesity	NOUN
amwa-432	30	8	the	the	DET
amwa-432	30	9	world	world	NOUN
amwa-432	30	10	health	health	NOUN
amwa-432	30	11	organization	organization	NOUN
amwa-432	30	12	defines	define	VERB
amwa-432	30	13	obesity	obesity	NOUN
amwa-432	30	14	as	as	ADP
amwa-432	30	15	uncontrolled	uncontrolled	ADJ
amwa-432	30	16	adipose	adipose	ADJ
amwa-432	30	17	accumulation	accumulation	NOUN
amwa-432	30	18	that	that	PRON
amwa-432	30	19	impairs	impair	VERB
amwa-432	30	20	health	health	NOUN
amwa-432	30	21	.	.	PUNCT
amwa-432	31	1	about	about	ADV
amwa-432	31	2	42	42	NUM
amwa-432	31	3	%	%	NOUN
amwa-432	31	4	of	of	ADP
amwa-432	31	5	us	us	PROPN
amwa-432	31	6	adults	adult	NOUN
amwa-432	31	7	meet	meet	VERB
amwa-432	31	8	criteria	criterion	NOUN
amwa-432	31	9	for	for	ADP
amwa-432	31	10	obesity	obesity	NOUN
amwa-432	31	11	,	,	PUNCT
amwa-432	31	12	and	and	CCONJ
amwa-432	31	13	the	the	DET
amwa-432	31	14	child	child	NOUN
amwa-432	31	15	and	and	CCONJ
amwa-432	31	16	adolescent	adolescent	ADJ
amwa-432	31	17	rate	rate	NOUN
amwa-432	31	18	has	have	AUX
amwa-432	31	19	almost	almost	ADV
amwa-432	31	20	quadrupled	quadruple	VERB
amwa-432	31	21	since	since	SCONJ
amwa-432	31	22	1990.4,5	1990.4,5	NUM
amwa-432	31	23	despite	despite	SCONJ
amwa-432	31	24	a	a	DET
amwa-432	31	25	century	century	NOUN
amwa-432	31	26	of	of	ADP
amwa-432	31	27	continued	continue	VERB
amwa-432	31	28	investigation	investigation	NOUN
amwa-432	31	29	,	,	PUNCT
amwa-432	31	30	our	our	PRON
amwa-432	31	31	understanding	understanding	NOUN
amwa-432	31	32	of	of	ADP
amwa-432	31	33	obesity	obesity	NOUN
amwa-432	31	34	as	as	ADP
amwa-432	31	35	a	a	DET
amwa-432	31	36	chronic	chronic	ADJ
amwa-432	31	37	disease	disease	NOUN
amwa-432	31	38	is	be	AUX
amwa-432	31	39	not	not	PART
amwa-432	31	40	shared	share	VERB
amwa-432	31	41	across	across	ADP
amwa-432	31	42	scientific	scientific	ADJ
amwa-432	31	43	,	,	PUNCT
amwa-432	31	44	public	public	ADJ
amwa-432	31	45	health	health	NOUN
amwa-432	31	46	,	,	PUNCT
amwa-432	31	47	or	or	CCONJ
amwa-432	31	48	political	political	ADJ
amwa-432	31	49	fields	field	NOUN
amwa-432	31	50	.	.	PUNCT
amwa-432	32	1	without	without	ADP
amwa-432	32	2	common	common	ADJ
amwa-432	32	3	symptoms	symptom	NOUN
amwa-432	32	4	or	or	CCONJ
amwa-432	32	5	diagnostic	diagnostic	ADJ
amwa-432	32	6	biomarkers	biomarker	NOUN
amwa-432	32	7	,	,	PUNCT
amwa-432	32	8	identifying	identify	VERB
amwa-432	32	9	the	the	DET
amwa-432	32	10	underlying	underlie	VERB
amwa-432	32	11	cause	cause	NOUN
amwa-432	32	12	for	for	ADP
amwa-432	32	13	adipose	adipose	ADJ
amwa-432	32	14	dysfunction	dysfunction	NOUN
amwa-432	32	15	remains	remain	VERB
amwa-432	32	16	difficult	difficult	ADJ
amwa-432	32	17	.	.	PUNCT
amwa-432	33	1	the	the	DET
amwa-432	33	2	controversy	controversy	NOUN
amwa-432	33	3	about	about	ADP
amwa-432	33	4	obesity	obesity	NOUN
amwa-432	33	5	influences	influence	VERB
amwa-432	33	6	social	social	ADJ
amwa-432	33	7	stigma	stigma	NOUN
amwa-432	33	8	,	,	PUNCT
amwa-432	33	9	clinical	clinical	ADJ
amwa-432	33	10	practice	practice	NOUN
amwa-432	33	11	,	,	PUNCT
amwa-432	33	12	public	public	ADJ
amwa-432	33	13	health	health	NOUN
amwa-432	33	14	policy	policy	NOUN
amwa-432	33	15	,	,	PUNCT
amwa-432	33	16	and	and	CCONJ
amwa-432	33	17	more	more	ADJ
amwa-432	33	18	.	.	PUNCT
amwa-432	34	1	evidence	evidence	NOUN
amwa-432	34	2	demonstrating	demonstrate	VERB
amwa-432	34	3	that	that	SCONJ
amwa-432	34	4	individuals	individual	NOUN
amwa-432	34	5	with	with	ADP
amwa-432	34	6	elevated	elevated	ADJ
amwa-432	34	7	bmi	bmi	NOUN
amwa-432	34	8	can	can	AUX
amwa-432	34	9	be	be	AUX
amwa-432	34	10	metabolically	metabolically	ADV
amwa-432	34	11	healthy	healthy	ADJ
amwa-432	34	12	contributes	contribute	VERB
amwa-432	34	13	to	to	ADP
amwa-432	34	14	the	the	DET
amwa-432	34	15	confusion.6	confusion.6	NOUN
amwa-432	34	16	defining	define	VERB
amwa-432	34	17	clinical	clinical	ADJ
amwa-432	34	18	obesity	obesity	NOUN
amwa-432	34	19	as	as	ADP
amwa-432	34	20	a	a	DET
amwa-432	34	21	higher	high	ADJ
amwa-432	34	22	visceral	visceral	ADJ
amwa-432	34	23	mass	mass	NOUN
amwa-432	34	24	associated	associate	VERB
amwa-432	34	25	with	with	ADP
amwa-432	34	26	an	an	DET
amwa-432	34	27	existing	exist	VERB
amwa-432	34	28	metabolic	metabolic	NOUN
amwa-432	34	29	dysfunction	dysfunction	NOUN
amwa-432	34	30	reflects	reflect	VERB
amwa-432	34	31	our	our	PRON
amwa-432	34	32	current	current	ADJ
amwa-432	34	33	understanding	understanding	NOUN
amwa-432	34	34	of	of	ADP
amwa-432	34	35	the	the	DET
amwa-432	34	36	adipose	adipose	NOUN
amwa-432	34	37	organ.7,8	organ.7,8	NOUN
amwa-432	34	38	this	this	DET
amwa-432	34	39	definition	definition	NOUN
amwa-432	34	40	links	link	VERB
amwa-432	34	41	visceral	visceral	ADJ
amwa-432	34	42	adipose	adipose	ADP
amwa-432	34	43	mass	mass	NOUN
amwa-432	34	44	to	to	ADP
amwa-432	34	45	metabolic	metabolic	NOUN
amwa-432	34	46	health	health	NOUN
amwa-432	34	47	rather	rather	ADV
amwa-432	34	48	than	than	ADP
amwa-432	34	49	body	body	NOUN
amwa-432	34	50	size	size	NOUN
amwa-432	34	51	,	,	PUNCT
amwa-432	34	52	weight	weight	NOUN
amwa-432	34	53	-	-	PUNCT
amwa-432	34	54	based	base	VERB
amwa-432	34	55	conditions	condition	NOUN
amwa-432	34	56	,	,	PUNCT
amwa-432	34	57	or	or	CCONJ
amwa-432	34	58	elevated	elevated	ADJ
amwa-432	34	59	bmi	bmi	NOUN
amwa-432	34	60	.	.	PUNCT
amwa-432	35	1	intra	intra	ADJ
amwa-432	35	2	-	-	ADJ
amwa-432	35	3	abdominal	abdominal	ADJ
amwa-432	35	4	distribution	distribution	NOUN
amwa-432	35	5	of	of	ADP
amwa-432	35	6	visceral	visceral	ADJ
amwa-432	35	7	adipose	adipose	ADJ
amwa-432	35	8	causes	cause	NOUN
amwa-432	35	9	chronic	chronic	ADJ
amwa-432	35	10	low	low	ADJ
amwa-432	35	11	-	-	PUNCT
amwa-432	35	12	grade	grade	NOUN
amwa-432	35	13	inflammation	inflammation	NOUN
amwa-432	35	14	,	,	PUNCT
amwa-432	35	15	hypertrophy	hypertrophy	NOUN
amwa-432	35	16	,	,	PUNCT
amwa-432	35	17	and	and	CCONJ
amwa-432	35	18	fibrosis	fibrosis	NOUN
amwa-432	35	19	with	with	ADP
amwa-432	35	20	increased	increase	VERB
amwa-432	35	21	health	health	NOUN
amwa-432	35	22	risks	risk	NOUN
amwa-432	35	23	(	(	PUNCT
amwa-432	35	24	figure	figure	NOUN
amwa-432	35	25	2).4	2).4	NOUN
amwa-432	35	26	in	in	ADP
amwa-432	35	27	2023	2023	NUM
amwa-432	35	28	,	,	PUNCT
amwa-432	35	29	the	the	DET
amwa-432	35	30	american	american	PROPN
amwa-432	35	31	medical	medical	PROPN
amwa-432	35	32	association	association	PROPN
amwa-432	35	33	(	(	PUNCT
amwa-432	35	34	ama	ama	NOUN
amwa-432	35	35	)	)	PUNCT
amwa-432	35	36	recognized	recognize	VERB
amwa-432	35	37	that	that	SCONJ
amwa-432	35	38	using	use	VERB
amwa-432	35	39	bmi	bmi	NOUN
amwa-432	35	40	as	as	ADP
amwa-432	35	41	the	the	DET
amwa-432	35	42	only	only	ADJ
amwa-432	35	43	defining	define	VERB
amwa-432	35	44	characteristic	characteristic	NOUN
amwa-432	35	45	for	for	ADP
amwa-432	35	46	obesity	obesity	NOUN
amwa-432	35	47	can	can	AUX
amwa-432	35	48	racially	racially	ADV
amwa-432	35	49	exclude	exclude	VERB
amwa-432	35	50	and	and	CCONJ
amwa-432	35	51	harm	harm	VERB
amwa-432	35	52	certain	certain	ADJ
amwa-432	35	53	individuals.9	individuals.9	NOUN
amwa-432	35	54	although	although	SCONJ
amwa-432	35	55	imaging	imaging	NOUN
amwa-432	35	56	modalities	modality	NOUN
amwa-432	35	57	more	more	ADV
amwa-432	35	58	precisely	precisely	ADV
amwa-432	35	59	calculate	calculate	VERB
amwa-432	35	60	adipose	adipose	ADJ
amwa-432	35	61	distribution	distribution	NOUN
amwa-432	35	62	,	,	PUNCT
amwa-432	35	63	the	the	DET
amwa-432	35	64	low	low	ADJ
amwa-432	35	65	cost	cost	NOUN
amwa-432	35	66	and	and	CCONJ
amwa-432	35	67	ease	ease	NOUN
amwa-432	35	68	of	of	ADP
amwa-432	35	69	application	application	NOUN
amwa-432	35	70	keeps	keep	VERB
amwa-432	35	71	bmi	bmi	NOUN
amwa-432	35	72	in	in	ADP
amwa-432	35	73	use	use	NOUN
amwa-432	35	74	.	.	PUNCT
amwa-432	36	1	variations	variation	NOUN
amwa-432	36	2	in	in	ADP
amwa-432	36	3	body	body	NOUN
amwa-432	36	4	shape	shape	NOUN
amwa-432	36	5	,	,	PUNCT
amwa-432	36	6	bone	bone	NOUN
amwa-432	36	7	mass	mass	NOUN
amwa-432	36	8	,	,	PUNCT
amwa-432	36	9	genetics	genetic	NOUN
amwa-432	36	10	,	,	PUNCT
amwa-432	36	11	and	and	CCONJ
amwa-432	36	12	waist	waist	NOUN
amwa-432	36	13	circumference	circumference	NOUN
amwa-432	36	14	can	can	AUX
amwa-432	36	15	alter	alter	VERB
amwa-432	36	16	the	the	DET
amwa-432	36	17	risk	risk	NOUN
amwa-432	36	18	estimate.8	estimate.8	NOUN
amwa-432	36	19	for	for	ADP
amwa-432	36	20	example	example	NOUN
amwa-432	36	21	,	,	PUNCT
amwa-432	36	22	bmi	bmi	VERB
amwa-432	36	23	fails	fail	VERB
amwa-432	36	24	to	to	PART
amwa-432	36	25	identify	identify	VERB
amwa-432	36	26	sarcopenic	sarcopenic	ADJ
amwa-432	36	27	obesity	obesity	NOUN
amwa-432	36	28	,	,	PUNCT
amwa-432	36	29	a	a	DET
amwa-432	36	30	loss	loss	NOUN
amwa-432	36	31	of	of	ADP
amwa-432	36	32	muscle	muscle	NOUN
amwa-432	36	33	mass	mass	NOUN
amwa-432	36	34	in	in	ADP
amwa-432	36	35	the	the	DET
amwa-432	36	36	presence	presence	NOUN
amwa-432	36	37	of	of	ADP
amwa-432	36	38	clinical	clinical	ADJ
amwa-432	36	39	obesity	obesity	NOUN
amwa-432	36	40	.	.	PUNCT
amwa-432	37	1	to	to	PART
amwa-432	37	2	resolve	resolve	VERB
amwa-432	37	3	this	this	PRON
amwa-432	37	4	,	,	PUNCT
amwa-432	37	5	the	the	DET
amwa-432	37	6	ama	ama	NOUN
amwa-432	37	7	recommends	recommend	VERB
amwa-432	37	8	combining	combine	VERB
amwa-432	37	9	bmi	bmi	NOUN
amwa-432	37	10	with	with	ADP
amwa-432	37	11	other	other	ADJ
amwa-432	37	12	indices.9	indices.9	NOUN
amwa-432	37	13	however	however	ADV
amwa-432	37	14	,	,	PUNCT
amwa-432	37	15	obesity	obesity	NOUN
amwa-432	37	16	clinical	clinical	ADJ
amwa-432	37	17	trials	trial	NOUN
amwa-432	37	18	and	and	CCONJ
amwa-432	37	19	population	population	NOUN
amwa-432	37	20	studies	study	NOUN
amwa-432	37	21	continue	continue	VERB
amwa-432	37	22	to	to	PART
amwa-432	37	23	use	use	VERB
amwa-432	37	24	bmi	bmi	NOUN
amwa-432	37	25	.	.	PUNCT
amwa-432	38	1	in	in	ADP
amwa-432	38	2	the	the	DET
amwa-432	38	3	past	past	ADJ
amwa-432	38	4	40	40	NUM
amwa-432	38	5	years	year	NOUN
amwa-432	38	6	,	,	PUNCT
amwa-432	38	7	the	the	DET
amwa-432	38	8	obesity	obesity	NOUN
amwa-432	38	9	pandemic	pandemic	ADJ
amwa-432	38	10	patterns	pattern	NOUN
amwa-432	38	11	have	have	AUX
amwa-432	38	12	changed	change	VERB
amwa-432	38	13	.	.	PUNCT
amwa-432	39	1	interestingly	interestingly	ADV
amwa-432	39	2	,	,	PUNCT
amwa-432	39	3	recent	recent	ADJ
amwa-432	39	4	urbanization	urbanization	NOUN
amwa-432	39	5	has	have	AUX
amwa-432	39	6	shifted	shift	VERB
amwa-432	39	7	the	the	DET
amwa-432	39	8	obesity	obesity	NOUN
amwa-432	39	9	prevalence	prevalence	NOUN
amwa-432	39	10	to	to	ADP
amwa-432	39	11	least	least	ADV
amwa-432	39	12	-	-	PUNCT
amwa-432	39	13	developed	develop	VERB
amwa-432	39	14	countries	country	NOUN
amwa-432	39	15	.	.	PUNCT
amwa-432	40	1	the	the	DET
amwa-432	40	2	influx	influx	NOUN
amwa-432	40	3	of	of	ADP
amwa-432	40	4	unprocessed	unprocessed	ADJ
amwa-432	40	5	,	,	PUNCT
amwa-432	40	6	high	high	ADJ
amwa-432	40	7	-	-	PUNCT
amwa-432	40	8	calorie	calorie	NOUN
amwa-432	40	9	foods	food	NOUN
amwa-432	40	10	and	and	CCONJ
amwa-432	40	11	other	other	ADJ
amwa-432	40	12	common	common	ADJ
amwa-432	40	13	drivers	driver	NOUN
amwa-432	40	14	may	may	AUX
amwa-432	40	15	contribute	contribute	VERB
amwa-432	40	16	to	to	ADP
amwa-432	40	17	the	the	DET
amwa-432	40	18	rising	rise	VERB
amwa-432	40	19	rates.10	rates.10	NOUN
amwa-432	40	20	in	in	ADP
amwa-432	40	21	children	child	NOUN
amwa-432	40	22	,	,	PUNCT
amwa-432	40	23	developmental	developmental	ADJ
amwa-432	40	24	factors	factor	NOUN
amwa-432	40	25	affecting	affect	VERB
amwa-432	40	26	weight	weight	NOUN
amwa-432	40	27	can	can	AUX
amwa-432	40	28	disrupt	disrupt	VERB
amwa-432	40	29	the	the	DET
amwa-432	40	30	balance	balance	NOUN
amwa-432	40	31	of	of	ADP
amwa-432	40	32	energy	energy	NOUN
amwa-432	40	33	intake	intake	NOUN
amwa-432	40	34	and	and	CCONJ
amwa-432	40	35	expenditure	expenditure	NOUN
amwa-432	40	36	.	.	PUNCT
amwa-432	41	1	these	these	DET
amwa-432	41	2	broad	broad	ADJ
amwa-432	41	3	environmental	environmental	ADJ
amwa-432	41	4	,	,	PUNCT
amwa-432	41	5	preconception	preconception	NOUN
amwa-432	41	6	,	,	PUNCT
amwa-432	41	7	and	and	CCONJ
amwa-432	41	8	prenatal	prenatal	ADJ
amwa-432	41	9	exposures	exposure	NOUN
amwa-432	41	10	are	be	AUX
amwa-432	41	11	risk	risk	NOUN
amwa-432	41	12	factors	factor	NOUN
amwa-432	41	13	for	for	ADP
amwa-432	41	14	obesity	obesity	NOUN
amwa-432	41	15	with	with	ADP
amwa-432	41	16	consequences	consequence	NOUN
amwa-432	41	17	into	into	ADP
amwa-432	41	18	adulthood.5	adulthood.5	PROPN
amwa-432	41	19	in	in	ADP
amwa-432	41	20	adults	adult	NOUN
amwa-432	41	21	,	,	PUNCT
amwa-432	41	22	complex	complex	ADJ
amwa-432	41	23	interconnected	interconnected	ADJ
amwa-432	41	24	risk	risk	NOUN
amwa-432	41	25	factors	factor	NOUN
amwa-432	41	26	influence	influence	VERB
amwa-432	41	27	weight:10	weight:10	VERB
amwa-432	41	28	•	•	NUM
amwa-432	41	29	biological	biological	ADJ
amwa-432	41	30	•	•	X
amwa-432	41	31	social	social	ADJ
amwa-432	41	32	•	•	NOUN
amwa-432	41	33	food	food	NOUN
amwa-432	41	34	industry	industry	NOUN
amwa-432	41	35	influences	influence	VERB
amwa-432	41	36	•	•	ADP
amwa-432	41	37	physical	physical	ADJ
amwa-432	41	38	safety	safety	NOUN
amwa-432	41	39	•	•	ADP
amwa-432	41	40	lived	live	VERB
amwa-432	41	41	experiences	experience	NOUN
amwa-432	41	42	evidence	evidence	NOUN
amwa-432	41	43	shows	show	VERB
amwa-432	41	44	a	a	DET
amwa-432	41	45	higher	high	ADJ
amwa-432	41	46	risk	risk	NOUN
amwa-432	41	47	of	of	ADP
amwa-432	41	48	developing	develop	VERB
amwa-432	41	49	obesity	obesity	NOUN
amwa-432	41	50	for	for	ADP
amwa-432	41	51	youth	youth	NOUN
amwa-432	41	52	living	live	VERB
amwa-432	41	53	in	in	ADP
amwa-432	41	54	lower	low	ADJ
amwa-432	41	55	social	social	ADJ
amwa-432	41	56	strata	strata	NOUN
amwa-432	41	57	or	or	CCONJ
amwa-432	41	58	exposed	expose	VERB
amwa-432	41	59	to	to	ADP
amwa-432	41	60	inequalities.5	inequalities.5	PROPN
amwa-432	41	61	similarly	similarly	ADV
amwa-432	41	62	,	,	PUNCT
amwa-432	41	63	racial	racial	ADJ
amwa-432	41	64	and	and	CCONJ
amwa-432	41	65	ethnic	ethnic	ADJ
amwa-432	41	66	disparities	disparity	NOUN
amwa-432	41	67	exist	exist	VERB
amwa-432	41	68	in	in	ADP
amwa-432	41	69	the	the	DET
amwa-432	41	70	prevalence	prevalence	NOUN
amwa-432	41	71	figure	figure	NOUN
amwa-432	42	1	2	2	NUM
amwa-432	42	2	.	.	PUNCT
amwa-432	42	3	health	health	NOUN
amwa-432	42	4	risks	risk	NOUN
amwa-432	42	5	related	relate	VERB
amwa-432	42	6	to	to	ADP
amwa-432	42	7	clinical	clinical	ADJ
amwa-432	42	8	obesity.4,5	obesity.4,5	NOUN
amwa-432	42	9	adult	adult	NOUN
amwa-432	42	10	is	be	AUX
amwa-432	42	11	defined	define	VERB
amwa-432	42	12	as	as	ADP
amwa-432	42	13	age	age	NOUN
amwa-432	42	14	≥20	≥20	NOUN
amwa-432	42	15	years	year	NOUN
amwa-432	42	16	,	,	PUNCT
amwa-432	42	17	and	and	CCONJ
amwa-432	42	18	youth	youth	NOUN
amwa-432	42	19	is	be	AUX
amwa-432	42	20	defined	define	VERB
amwa-432	42	21	as	as	ADP
amwa-432	42	22	age	age	NOUN
amwa-432	42	23	2	2	NUM
amwa-432	42	24	-	-	SYM
amwa-432	42	25	19	19	NUM
amwa-432	42	26	years	year	NOUN
amwa-432	42	27	.	.	PUNCT
amwa-432	43	1	gerd	gerd	NOUN
amwa-432	43	2	,	,	PUNCT
amwa-432	43	3	gastroesophageal	gastroesophageal	VERB
amwa-432	43	4	reflux	reflux	NOUN
amwa-432	43	5	disease	disease	NOUN
amwa-432	43	6	;	;	PUNCT
amwa-432	43	7	gi	gi	INTJ
amwa-432	43	8	,	,	PUNCT
amwa-432	43	9	gastrointestinal	gastrointestinal	ADJ
amwa-432	43	10	;	;	PUNCT
amwa-432	43	11	pcos	pco	NOUN
amwa-432	43	12	,	,	PUNCT
amwa-432	43	13	polycystic	polycystic	ADJ
amwa-432	43	14	ovarian	ovarian	ADJ
amwa-432	43	15	syndrome	syndrome	NOUN
amwa-432	43	16	.	.	PUNCT
amwa-432	43	17	http://www.amwajournal.org	http://www.amwajournal.org	X
amwa-432	44	1	amwajournal.org	amwajournal.org	X
amwa-432	44	2	37incretin	37incretin	NUM
amwa-432	44	3	drug	drug	NOUN
amwa-432	44	4	revolution	revolution	NOUN
amwa-432	44	5	:	:	PUNCT
amwa-432	44	6	the	the	DET
amwa-432	44	7	challenges	challenge	NOUN
amwa-432	44	8	of	of	ADP
amwa-432	44	9	hope	hope	NOUN
amwa-432	44	10	for	for	ADP
amwa-432	44	11	obesity	obesity	NOUN
amwa-432	44	12	in	in	ADP
amwa-432	44	13	the	the	DET
amwa-432	44	14	united	united	PROPN
amwa-432	44	15	states	states	PROPN
amwa-432	44	16	(	(	PUNCT
amwa-432	44	17	figure	figure	NOUN
amwa-432	44	18	3	3	NUM
amwa-432	44	19	)	)	PUNCT
amwa-432	44	20	.	.	PUNCT
amwa-432	45	1	the	the	DET
amwa-432	45	2	increased	increase	VERB
amwa-432	45	3	prevalence	prevalence	NOUN
amwa-432	45	4	of	of	ADP
amwa-432	45	5	obesity	obesity	NOUN
amwa-432	45	6	in	in	ADP
amwa-432	45	7	black	black	ADJ
amwa-432	45	8	and	and	CCONJ
amwa-432	45	9	hispanic	hispanic	ADJ
amwa-432	45	10	adults	adult	NOUN
amwa-432	45	11	underscores	underscore	VERB
amwa-432	45	12	the	the	DET
amwa-432	45	13	need	need	NOUN
amwa-432	45	14	for	for	ADP
amwa-432	45	15	diversity	diversity	NOUN
amwa-432	45	16	in	in	ADP
amwa-432	45	17	obesity	obesity	NOUN
amwa-432	45	18	clinical	clinical	ADJ
amwa-432	45	19	trials	trial	NOUN
amwa-432	45	20	.	.	PUNCT
amwa-432	46	1	lack	lack	NOUN
amwa-432	46	2	of	of	ADP
amwa-432	46	3	diversity	diversity	NOUN
amwa-432	46	4	in	in	ADP
amwa-432	46	5	clinical	clinical	ADJ
amwa-432	46	6	trials	trial	NOUN
amwa-432	46	7	for	for	ADP
amwa-432	46	8	obesity	obesity	NOUN
amwa-432	46	9	clinical	clinical	ADJ
amwa-432	46	10	trials	trial	NOUN
amwa-432	46	11	for	for	ADP
amwa-432	46	12	obesity	obesity	NOUN
amwa-432	46	13	should	should	AUX
amwa-432	46	14	accurately	accurately	ADV
amwa-432	46	15	reflect	reflect	VERB
amwa-432	46	16	the	the	DET
amwa-432	46	17	characteristics	characteristic	NOUN
amwa-432	46	18	of	of	ADP
amwa-432	46	19	the	the	DET
amwa-432	46	20	disease	disease	NOUN
amwa-432	46	21	population.13	population.13	NOUN
amwa-432	46	22	but	but	CCONJ
amwa-432	46	23	a	a	DET
amwa-432	46	24	recent	recent	ADJ
amwa-432	46	25	meta	meta	ADJ
amwa-432	46	26	-	-	PUNCT
amwa-432	46	27	analysis	analysis	NOUN
amwa-432	46	28	revealed	reveal	VERB
amwa-432	46	29	that	that	SCONJ
amwa-432	46	30	obesity	obesity	NOUN
amwa-432	46	31	clinical	clinical	ADJ
amwa-432	46	32	trial	trial	NOUN
amwa-432	46	33	participants	participant	NOUN
amwa-432	46	34	comprised	comprise	VERB
amwa-432	46	35	of	of	ADP
amwa-432	46	36	74	74	NUM
amwa-432	46	37	%	%	NOUN
amwa-432	46	38	white	white	ADJ
amwa-432	46	39	adults	adult	NOUN
amwa-432	46	40	,	,	PUNCT
amwa-432	46	41	mainly	mainly	ADV
amwa-432	46	42	women	woman	NOUN
amwa-432	46	43	(	(	PUNCT
amwa-432	46	44	table	table	NOUN
amwa-432	46	45	1).13	1).13	NUM
amwa-432	46	46	in	in	ADP
amwa-432	46	47	the	the	DET
amwa-432	46	48	united	united	PROPN
amwa-432	46	49	states	states	PROPN
amwa-432	46	50	,	,	PUNCT
amwa-432	46	51	the	the	DET
amwa-432	46	52	cdc	cdc	PROPN
amwa-432	46	53	reports	report	VERB
amwa-432	46	54	the	the	DET
amwa-432	46	55	highest	high	ADJ
amwa-432	46	56	risk	risk	NOUN
amwa-432	46	57	for	for	ADP
amwa-432	46	58	obesity	obesity	NOUN
amwa-432	46	59	in	in	ADP
amwa-432	46	60	black	black	ADJ
amwa-432	46	61	(	(	PUNCT
amwa-432	46	62	50	50	NUM
amwa-432	46	63	%	%	NOUN
amwa-432	46	64	)	)	PUNCT
amwa-432	46	65	and	and	CCONJ
amwa-432	46	66	hispanic	hispanic	ADJ
amwa-432	46	67	(	(	PUNCT
amwa-432	46	68	45	45	NUM
amwa-432	46	69	%	%	NOUN
amwa-432	46	70	)	)	PUNCT
amwa-432	46	71	adults	adult	NOUN
amwa-432	46	72	,	,	PUNCT
amwa-432	46	73	but	but	CCONJ
amwa-432	46	74	only	only	ADV
amwa-432	46	75	18	18	NUM
amwa-432	46	76	%	%	NOUN
amwa-432	46	77	black	black	ADJ
amwa-432	46	78	and	and	CCONJ
amwa-432	46	79	19	19	NUM
amwa-432	46	80	%	%	NOUN
amwa-432	46	81	hispanic	hispanic	ADJ
amwa-432	46	82	adults	adult	NOUN
amwa-432	46	83	participated	participate	VERB
amwa-432	46	84	in	in	ADP
amwa-432	46	85	the	the	DET
amwa-432	46	86	drug	drug	NOUN
amwa-432	46	87	trials.13	trials.13	NOUN
amwa-432	46	88	this	this	DET
amwa-432	46	89	lack	lack	NOUN
amwa-432	46	90	of	of	ADP
amwa-432	46	91	diversity	diversity	NOUN
amwa-432	46	92	during	during	ADP
amwa-432	46	93	obesity	obesity	NOUN
amwa-432	46	94	drug	drug	NOUN
amwa-432	46	95	testing	testing	NOUN
amwa-432	46	96	creates	create	VERB
amwa-432	46	97	a	a	DET
amwa-432	46	98	gap	gap	NOUN
amwa-432	46	99	in	in	ADP
amwa-432	46	100	understanding	understand	VERB
amwa-432	46	101	the	the	DET
amwa-432	46	102	risks	risk	NOUN
amwa-432	46	103	and	and	CCONJ
amwa-432	46	104	benefits	benefit	NOUN
amwa-432	46	105	of	of	ADP
amwa-432	46	106	obesity	obesity	NOUN
amwa-432	46	107	therapies	therapy	NOUN
amwa-432	46	108	for	for	ADP
amwa-432	46	109	diverse	diverse	ADJ
amwa-432	46	110	populations	population	NOUN
amwa-432	46	111	.	.	PUNCT
amwa-432	47	1	future	future	ADJ
amwa-432	47	2	studies	study	NOUN
amwa-432	47	3	aim	aim	VERB
amwa-432	47	4	to	to	PART
amwa-432	47	5	increase	increase	VERB
amwa-432	47	6	diversity	diversity	NOUN
amwa-432	47	7	by	by	ADP
amwa-432	47	8	decentralizing	decentralize	VERB
amwa-432	47	9	clinical	clinical	ADJ
amwa-432	47	10	trial	trial	NOUN
amwa-432	47	11	centers	center	NOUN
amwa-432	47	12	.	.	PUNCT
amwa-432	48	1	but	but	CCONJ
amwa-432	48	2	some	some	PRON
amwa-432	48	3	of	of	ADP
amwa-432	48	4	the	the	DET
amwa-432	48	5	difficulty	difficulty	NOUN
amwa-432	48	6	surrounding	surround	VERB
amwa-432	48	7	diversity	diversity	NOUN
amwa-432	48	8	in	in	ADP
amwa-432	48	9	testing	testing	NOUN
amwa-432	48	10	is	be	AUX
amwa-432	48	11	the	the	DET
amwa-432	48	12	need	need	NOUN
amwa-432	48	13	for	for	ADP
amwa-432	48	14	clear	clear	ADJ
amwa-432	48	15	guidance	guidance	NOUN
amwa-432	48	16	in	in	ADP
amwa-432	48	17	clinical	clinical	ADJ
amwa-432	48	18	obesity	obesity	NOUN
amwa-432	48	19	care	care	NOUN
amwa-432	48	20	.	.	PUNCT
amwa-432	49	1	guiding	guide	VERB
amwa-432	49	2	clinical	clinical	ADJ
amwa-432	49	3	care	care	NOUN
amwa-432	49	4	for	for	ADP
amwa-432	49	5	obesity	obesity	NOUN
amwa-432	49	6	evidence	evidence	NOUN
amwa-432	49	7	suggests	suggest	VERB
amwa-432	49	8	that	that	SCONJ
amwa-432	49	9	lifestyle	lifestyle	NOUN
amwa-432	49	10	modification	modification	NOUN
amwa-432	49	11	and	and	CCONJ
amwa-432	49	12	physical	physical	ADJ
amwa-432	49	13	activity	activity	NOUN
amwa-432	49	14	remain	remain	VERB
amwa-432	49	15	cornerstones	cornerstone	NOUN
amwa-432	49	16	for	for	ADP
amwa-432	49	17	optimizing	optimize	VERB
amwa-432	49	18	health	health	NOUN
amwa-432	49	19	but	but	CCONJ
amwa-432	49	20	only	only	ADV
amwa-432	49	21	provide	provide	VERB
amwa-432	49	22	minimal	minimal	ADJ
amwa-432	49	23	reductions	reduction	NOUN
amwa-432	49	24	in	in	ADP
amwa-432	49	25	weight	weight	NOUN
amwa-432	49	26	.	.	PUNCT
amwa-432	50	1	using	use	VERB
amwa-432	50	2	these	these	DET
amwa-432	50	3	data	datum	NOUN
amwa-432	50	4	,	,	PUNCT
amwa-432	50	5	all	all	DET
amwa-432	50	6	guidelines	guideline	NOUN
amwa-432	50	7	suggest	suggest	VERB
amwa-432	50	8	pharmacotherapy	pharmacotherapy	NOUN
amwa-432	50	9	for	for	ADP
amwa-432	50	10	adults	adult	NOUN
amwa-432	50	11	who	who	PRON
amwa-432	50	12	are	be	AUX
amwa-432	50	13	not	not	PART
amwa-432	50	14	pregnant	pregnant	ADJ
amwa-432	50	15	and	and	CCONJ
amwa-432	50	16	have	have	VERB
amwa-432	50	17	a	a	DET
amwa-432	50	18	bmi	bmi	NOUN
amwa-432	50	19	≥27	≥27	NOUN
amwa-432	50	20	in	in	ADP
amwa-432	50	21	the	the	DET
amwa-432	50	22	presence	presence	NOUN
amwa-432	50	23	of	of	ADP
amwa-432	50	24	a	a	DET
amwa-432	50	25	weight	weight	NOUN
amwa-432	50	26	related	relate	VERB
amwa-432	50	27	condition	condition	NOUN
amwa-432	50	28	or	or	CCONJ
amwa-432	50	29	a	a	DET
amwa-432	50	30	bmi	bmi	NOUN
amwa-432	50	31	of	of	ADP
amwa-432	50	32	≥30.14	≥30.14	PRON
amwa-432	50	33	similarly	similarly	ADV
amwa-432	50	34	,	,	PUNCT
amwa-432	50	35	the	the	DET
amwa-432	50	36	american	american	PROPN
amwa-432	50	37	academy	academy	PROPN
amwa-432	50	38	of	of	ADP
amwa-432	50	39	pediatrics	pediatric	NOUN
amwa-432	50	40	recommends	recommend	VERB
amwa-432	50	41	pharmacotherapy	pharmacotherapy	NOUN
amwa-432	50	42	for	for	ADP
amwa-432	50	43	children	child	NOUN
amwa-432	50	44	8	8	NUM
amwa-432	50	45	years	year	NOUN
amwa-432	50	46	and	and	CCONJ
amwa-432	50	47	older	old	ADJ
amwa-432	50	48	who	who	PRON
amwa-432	50	49	meet	meet	VERB
amwa-432	50	50	criteria	criterion	NOUN
amwa-432	50	51	for	for	ADP
amwa-432	50	52	obesity.11	obesity.11	NOUN
amwa-432	50	53	the	the	DET
amwa-432	50	54	latest	late	ADJ
amwa-432	50	55	clinical	clinical	ADJ
amwa-432	50	56	guidelines	guideline	NOUN
amwa-432	50	57	for	for	ADP
amwa-432	50	58	individuals	individual	NOUN
amwa-432	50	59	with	with	ADP
amwa-432	50	60	obesity	obesity	NOUN
amwa-432	50	61	tether	tether	NOUN
amwa-432	50	62	lifestyle	lifestyle	NOUN
amwa-432	50	63	modification	modification	NOUN
amwa-432	50	64	to	to	ADP
amwa-432	50	65	all	all	DET
amwa-432	50	66	pharmacotherapy	pharmacotherapy	NOUN
amwa-432	50	67	treatment	treatment	NOUN
amwa-432	50	68	,	,	PUNCT
amwa-432	50	69	tailoring	tailor	VERB
amwa-432	50	70	therapy	therapy	NOUN
amwa-432	50	71	to	to	ADP
amwa-432	50	72	each	each	DET
amwa-432	50	73	individual.14	individual.14	PROPN
amwa-432	50	74	thus	thus	ADV
amwa-432	50	75	,	,	PUNCT
amwa-432	50	76	for	for	ADP
amwa-432	50	77	treatment	treatment	NOUN
amwa-432	50	78	optimization	optimization	NOUN
amwa-432	50	79	,	,	PUNCT
amwa-432	50	80	clinicians	clinician	NOUN
amwa-432	50	81	need	need	VERB
amwa-432	50	82	a	a	DET
amwa-432	50	83	wide	wide	ADJ
amwa-432	50	84	range	range	NOUN
amwa-432	50	85	of	of	ADP
amwa-432	50	86	effective	effective	ADJ
amwa-432	50	87	and	and	CCONJ
amwa-432	50	88	safe	safe	ADJ
amwa-432	50	89	medications	medication	NOUN
amwa-432	50	90	for	for	ADP
amwa-432	50	91	obesity.15	obesity.15	PROPN
amwa-432	50	92	because	because	SCONJ
amwa-432	50	93	a	a	DET
amwa-432	50	94	large	large	ADJ
amwa-432	50	95	body	body	NOUN
amwa-432	50	96	of	of	ADP
amwa-432	50	97	evidence	evidence	NOUN
amwa-432	50	98	suggests	suggest	VERB
amwa-432	50	99	that	that	SCONJ
amwa-432	50	100	weight	weight	NOUN
amwa-432	50	101	reductions	reduction	NOUN
amwa-432	50	102	between	between	ADP
amwa-432	50	103	10	10	NUM
amwa-432	50	104	%	%	NOUN
amwa-432	50	105	and	and	CCONJ
amwa-432	50	106	15	15	NUM
amwa-432	50	107	%	%	NOUN
amwa-432	50	108	improves	improve	VERB
amwa-432	50	109	cardiometabolic	cardiometabolic	ADJ
amwa-432	50	110	health	health	NOUN
amwa-432	50	111	,	,	PUNCT
amwa-432	50	112	guidelines	guideline	NOUN
amwa-432	50	113	aim	aim	VERB
amwa-432	50	114	for	for	ADP
amwa-432	50	115	reductions	reduction	NOUN
amwa-432	50	116	of	of	ADP
amwa-432	50	117	≥10%.4	≥10%.4	PRON
amwa-432	50	118	yet	yet	ADV
amwa-432	50	119	before	before	ADP
amwa-432	50	120	2021	2021	NUM
amwa-432	50	121	,	,	PUNCT
amwa-432	50	122	most	most	ADJ
amwa-432	50	123	clinical	clinical	ADJ
amwa-432	50	124	trial	trial	NOUN
amwa-432	50	125	participants	participant	NOUN
amwa-432	50	126	reported	report	VERB
amwa-432	50	127	obesity	obesity	NOUN
amwa-432	50	128	drug	drug	NOUN
amwa-432	50	129	inefficacy	inefficacy	NOUN
amwa-432	50	130	rates	rate	NOUN
amwa-432	50	131	ranging	range	VERB
amwa-432	50	132	from	from	ADP
amwa-432	50	133	59	59	NUM
amwa-432	50	134	%	%	NOUN
amwa-432	50	135	to	to	PART
amwa-432	50	136	80	80	NUM
amwa-432	50	137	%	%	NOUN
amwa-432	50	138	(	(	PUNCT
amwa-432	50	139	figure	figure	NOUN
amwa-432	50	140	5	5	NUM
amwa-432	50	141	)	)	PUNCT
amwa-432	50	142	.	.	PUNCT
amwa-432	51	1	as	as	ADP
amwa-432	51	2	an	an	DET
amwa-432	51	3	alternative	alternative	NOUN
amwa-432	51	4	,	,	PUNCT
amwa-432	51	5	bariatric	bariatric	ADJ
amwa-432	51	6	surgery	surgery	NOUN
amwa-432	51	7	became	become	VERB
amwa-432	51	8	a	a	DET
amwa-432	51	9	standard	standard	ADJ
amwa-432	51	10	obesity	obesity	NOUN
amwa-432	51	11	option	option	NOUN
amwa-432	51	12	as	as	ADP
amwa-432	51	13	part	part	NOUN
amwa-432	51	14	of	of	ADP
amwa-432	51	15	a	a	DET
amwa-432	51	16	flexible	flexible	ADJ
amwa-432	51	17	care	care	NOUN
amwa-432	51	18	approach	approach	NOUN
amwa-432	51	19	.	.	PUNCT
amwa-432	52	1	for	for	ADP
amwa-432	52	2	some	some	DET
amwa-432	52	3	patients	patient	NOUN
amwa-432	52	4	,	,	PUNCT
amwa-432	52	5	bariatric	bariatric	ADJ
amwa-432	52	6	surgery	surgery	NOUN
amwa-432	52	7	remains	remain	VERB
amwa-432	52	8	a	a	DET
amwa-432	52	9	viable	viable	ADJ
amwa-432	52	10	long	long	ADJ
amwa-432	52	11	-	-	PUNCT
amwa-432	52	12	term	term	NOUN
amwa-432	52	13	solution	solution	NOUN
amwa-432	52	14	,	,	PUNCT
amwa-432	52	15	improving	improve	VERB
amwa-432	52	16	glucose	glucose	NOUN
amwa-432	52	17	and	and	CCONJ
amwa-432	52	18	lipid	lipid	NOUN
amwa-432	52	19	levels.4	levels.4	PROPN
amwa-432	52	20	however	however	ADV
amwa-432	52	21	,	,	PUNCT
amwa-432	52	22	postsurgical	postsurgical	ADJ
amwa-432	52	23	complications	complication	NOUN
amwa-432	52	24	combined	combine	VERB
amwa-432	52	25	with	with	ADP
amwa-432	52	26	facility	facility	NOUN
amwa-432	52	27	and	and	CCONJ
amwa-432	52	28	specialist	specialist	NOUN
amwa-432	52	29	requirements	requirement	NOUN
amwa-432	52	30	limit	limit	VERB
amwa-432	52	31	widespread	widespread	ADJ
amwa-432	52	32	use	use	NOUN
amwa-432	52	33	.	.	PUNCT
amwa-432	53	1	the	the	DET
amwa-432	53	2	success	success	NOUN
amwa-432	53	3	of	of	ADP
amwa-432	53	4	individualized	individualized	ADJ
amwa-432	53	5	obesity	obesity	NOUN
amwa-432	53	6	care	care	NOUN
amwa-432	53	7	plans	plan	NOUN
amwa-432	53	8	depends	depend	VERB
amwa-432	53	9	on	on	ADP
amwa-432	53	10	identifying	identify	VERB
amwa-432	53	11	individuals	individual	NOUN
amwa-432	53	12	for	for	ADP
amwa-432	53	13	treatment	treatment	NOUN
amwa-432	53	14	and	and	CCONJ
amwa-432	53	15	applying	apply	VERB
amwa-432	53	16	the	the	DET
amwa-432	53	17	correct	correct	ADJ
amwa-432	53	18	therapy	therapy	NOUN
amwa-432	53	19	at	at	ADP
amwa-432	53	20	the	the	DET
amwa-432	53	21	right	right	ADJ
amwa-432	53	22	time	time	NOUN
amwa-432	53	23	.	.	PUNCT
amwa-432	54	1	health	health	NOUN
amwa-432	54	2	care	care	NOUN
amwa-432	54	3	providers	provider	NOUN
amwa-432	54	4	remember	remember	VERB
amwa-432	54	5	the	the	DET
amwa-432	54	6	past	past	NOUN
amwa-432	54	7	and	and	CCONJ
amwa-432	54	8	remain	remain	VERB
amwa-432	54	9	vigilant	vigilant	ADJ
amwa-432	54	10	when	when	SCONJ
amwa-432	54	11	prescribing	prescribe	VERB
amwa-432	54	12	new	new	ADJ
amwa-432	54	13	obesity	obesity	NOUN
amwa-432	54	14	drugs	drug	NOUN
amwa-432	54	15	.	.	PUNCT
amwa-432	55	1	however	however	ADV
amwa-432	55	2	,	,	PUNCT
amwa-432	55	3	media	medium	NOUN
amwa-432	55	4	attention	attention	NOUN
amwa-432	55	5	drives	drive	VERB
amwa-432	55	6	the	the	DET
amwa-432	55	7	demand	demand	NOUN
amwa-432	55	8	for	for	ADP
amwa-432	55	9	incretin	incretin	ADJ
amwa-432	55	10	drugs	drug	NOUN
amwa-432	55	11	,	,	PUNCT
amwa-432	55	12	highlighting	highlight	VERB
amwa-432	55	13	drug	drug	NOUN
amwa-432	55	14	claims	claim	NOUN
amwa-432	55	15	of	of	ADP
amwa-432	55	16	lowered	lower	VERB
amwa-432	55	17	glycemic	glycemic	ADJ
amwa-432	55	18	index	index	NOUN
amwa-432	55	19	,	,	PUNCT
amwa-432	55	20	cardiovascular	cardiovascular	ADJ
amwa-432	55	21	risk	risk	NOUN
amwa-432	55	22	,	,	PUNCT
amwa-432	55	23	and	and	CCONJ
amwa-432	55	24	weight	weight	NOUN
amwa-432	55	25	loss	loss	NOUN
amwa-432	55	26	of	of	ADP
amwa-432	55	27	20	20	NUM
amwa-432	55	28	%	%	NOUN
amwa-432	55	29	or	or	CCONJ
amwa-432	55	30	more.16	more.16	PROPN
amwa-432	55	31	although	although	SCONJ
amwa-432	55	32	incretin	incretin	NOUN
amwa-432	55	33	therapies	therapy	NOUN
amwa-432	55	34	may	may	AUX
amwa-432	55	35	fill	fill	VERB
amwa-432	55	36	the	the	DET
amwa-432	55	37	therapeutic	therapeutic	ADJ
amwa-432	55	38	gap	gap	NOUN
amwa-432	55	39	between	between	ADP
amwa-432	55	40	lifestyle	lifestyle	NOUN
amwa-432	55	41	modification	modification	NOUN
amwa-432	55	42	and	and	CCONJ
amwa-432	55	43	surgery	surgery	NOUN
amwa-432	55	44	,	,	PUNCT
amwa-432	55	45	balancing	balance	VERB
amwa-432	55	46	health	health	NOUN
amwa-432	55	47	benefits	benefit	NOUN
amwa-432	55	48	with	with	ADP
amwa-432	55	49	risks	risk	NOUN
amwa-432	55	50	remains	remain	VERB
amwa-432	55	51	important	important	ADJ
amwa-432	55	52	when	when	SCONJ
amwa-432	55	53	choosing	choose	VERB
amwa-432	55	54	drug	drug	NOUN
amwa-432	55	55	treatment	treatment	NOUN
amwa-432	55	56	.	.	PUNCT
amwa-432	56	1	approved	approve	VERB
amwa-432	56	2	long	long	ADJ
amwa-432	56	3	-	-	PUNCT
amwa-432	56	4	term	term	NOUN
amwa-432	56	5	pharmacotherapies	pharmacotherapie	NOUN
amwa-432	56	6	for	for	ADP
amwa-432	56	7	clinical	clinical	ADJ
amwa-432	56	8	obesity	obesity	NOUN
amwa-432	56	9	in	in	ADP
amwa-432	56	10	the	the	DET
amwa-432	56	11	united	united	PROPN
amwa-432	56	12	states	states	PROPN
amwa-432	56	13	,	,	PUNCT
amwa-432	56	14	6	6	NUM
amwa-432	56	15	long	long	ADJ
amwa-432	56	16	-	-	PUNCT
amwa-432	56	17	term	term	NOUN
amwa-432	56	18	drugs	drug	NOUN
amwa-432	56	19	treat	treat	VERB
amwa-432	56	20	clinical	clinical	ADJ
amwa-432	56	21	obesity	obesity	NOUN
amwa-432	56	22	,	,	PUNCT
amwa-432	56	23	mainly	mainly	ADV
amwa-432	56	24	targeting	target	VERB
amwa-432	56	25	weight	weight	NOUN
amwa-432	56	26	loss	loss	NOUN
amwa-432	56	27	(	(	PUNCT
amwa-432	56	28	table	table	NOUN
amwa-432	56	29	1	1	NUM
amwa-432	56	30	)	)	PUNCT
amwa-432	56	31	.	.	PUNCT
amwa-432	57	1	like	like	ADP
amwa-432	57	2	any	any	DET
amwa-432	57	3	treatment	treatment	NOUN
amwa-432	57	4	,	,	PUNCT
amwa-432	57	5	balancing	balance	VERB
amwa-432	57	6	health	health	NOUN
amwa-432	57	7	benefits	benefit	NOUN
amwa-432	57	8	with	with	ADP
amwa-432	57	9	risk	risk	NOUN
amwa-432	57	10	helps	help	VERB
amwa-432	57	11	optimize	optimize	VERB
amwa-432	57	12	care	care	NOUN
amwa-432	57	13	.	.	PUNCT
amwa-432	58	1	yet	yet	ADV
amwa-432	58	2	without	without	ADP
amwa-432	58	3	robust	robust	ADJ
amwa-432	58	4	,	,	PUNCT
amwa-432	58	5	independent	independent	ADJ
amwa-432	58	6	clinical	clinical	ADJ
amwa-432	58	7	trials	trial	NOUN
amwa-432	58	8	comparing	compare	VERB
amwa-432	58	9	treatments	treatment	NOUN
amwa-432	58	10	,	,	PUNCT
amwa-432	58	11	doctors	doctor	NOUN
amwa-432	58	12	typically	typically	ADV
amwa-432	58	13	use	use	VERB
amwa-432	58	14	trial	trial	NOUN
amwa-432	58	15	-	-	PUNCT
amwa-432	58	16	and	and	CCONJ
amwa-432	58	17	-	-	PUNCT
amwa-432	58	18	error	error	NOUN
amwa-432	58	19	when	when	SCONJ
amwa-432	58	20	prescribing	prescribe	VERB
amwa-432	58	21	obesity	obesity	NOUN
amwa-432	58	22	drugs	drug	NOUN
amwa-432	58	23	.	.	PUNCT
amwa-432	59	1	another	another	DET
amwa-432	59	2	common	common	ADJ
amwa-432	59	3	practice	practice	NOUN
amwa-432	59	4	is	be	AUX
amwa-432	59	5	off	off	ADP
amwa-432	59	6	-	-	PUNCT
amwa-432	59	7	label	label	NOUN
amwa-432	59	8	use	use	NOUN
amwa-432	59	9	of	of	ADP
amwa-432	59	10	low	low	ADJ
amwa-432	59	11	-	-	PUNCT
amwa-432	59	12	cost	cost	NOUN
amwa-432	59	13	therapies	therapy	NOUN
amwa-432	59	14	.	.	PUNCT
amwa-432	60	1	for	for	ADP
amwa-432	60	2	example	example	NOUN
amwa-432	60	3	,	,	PUNCT
amwa-432	60	4	phentermine	phentermine	NOUN
amwa-432	60	5	and	and	CCONJ
amwa-432	60	6	topiramate	topiramate	NOUN
amwa-432	60	7	are	be	AUX
amwa-432	60	8	2	2	NUM
amwa-432	60	9	of	of	ADP
amwa-432	60	10	the	the	DET
amwa-432	60	11	most	most	ADV
amwa-432	60	12	used	used	ADJ
amwa-432	60	13	drugs	drug	NOUN
amwa-432	60	14	in	in	ADP
amwa-432	60	15	pediatrics	pediatric	NOUN
amwa-432	60	16	.	.	PUNCT
amwa-432	61	1	although	although	SCONJ
amwa-432	61	2	phentermine	phentermine	NOUN
amwa-432	61	3	is	be	AUX
amwa-432	61	4	approved	approve	VERB
amwa-432	61	5	for	for	ADP
amwa-432	61	6	short	short	ADJ
amwa-432	61	7	-	-	PUNCT
amwa-432	61	8	term	term	NOUN
amwa-432	61	9	weight	weight	NOUN
amwa-432	61	10	loss	loss	NOUN
amwa-432	61	11	in	in	ADP
amwa-432	61	12	children	child	NOUN
amwa-432	61	13	,	,	PUNCT
amwa-432	61	14	topiramate	topiramate	NOUN
amwa-432	61	15	is	be	AUX
amwa-432	61	16	not	not	PART
amwa-432	61	17	.	.	PUNCT
amwa-432	62	1	but	but	CCONJ
amwa-432	62	2	phentermine	phentermine	NOUN
amwa-432	62	3	with	with	ADP
amwa-432	62	4	topiramate	topiramate	ADJ
amwa-432	62	5	(	(	PUNCT
amwa-432	62	6	phen	phen	NOUN
amwa-432	62	7	/	/	SYM
amwa-432	62	8	top	top	NOUN
amwa-432	62	9	)	)	PUNCT
amwa-432	62	10	is	be	AUX
amwa-432	62	11	approved	approve	VERB
amwa-432	62	12	for	for	ADP
amwa-432	62	13	long	long	ADJ
amwa-432	62	14	-	-	PUNCT
amwa-432	62	15	term	term	NOUN
amwa-432	62	16	weight	weight	NOUN
amwa-432	62	17	loss	loss	NOUN
amwa-432	62	18	in	in	ADP
amwa-432	62	19	patients	patient	NOUN
amwa-432	62	20	12	12	NUM
amwa-432	62	21	years	year	NOUN
amwa-432	62	22	and	and	CCONJ
amwa-432	62	23	older	old	ADJ
amwa-432	62	24	.	.	PUNCT
amwa-432	63	1	topiramate	topiramate	NOUN
amwa-432	63	2	,	,	PUNCT
amwa-432	63	3	an	an	DET
amwa-432	63	4	antiepileptic	antiepileptic	ADJ
amwa-432	63	5	drug	drug	NOUN
amwa-432	63	6	,	,	PUNCT
amwa-432	63	7	can	can	AUX
amwa-432	63	8	affect	affect	VERB
amwa-432	63	9	cognition	cognition	NOUN
amwa-432	63	10	,	,	PUNCT
amwa-432	63	11	sleep	sleep	NOUN
amwa-432	63	12	,	,	PUNCT
amwa-432	63	13	and	and	CCONJ
amwa-432	63	14	memory	memory	NOUN
amwa-432	63	15	;	;	PUNCT
amwa-432	63	16	because	because	SCONJ
amwa-432	63	17	of	of	ADP
amwa-432	63	18	carbonic	carbonic	ADJ
amwa-432	63	19	anhydrase	anhydrase	NOUN
amwa-432	63	20	inhibition	inhibition	NOUN
amwa-432	63	21	,	,	PUNCT
amwa-432	63	22	the	the	DET
amwa-432	63	23	compound	compound	NOUN
amwa-432	63	24	also	also	ADV
amwa-432	63	25	increases	increase	VERB
amwa-432	63	26	risk	risk	NOUN
amwa-432	63	27	of	of	ADP
amwa-432	63	28	taste	taste	NOUN
amwa-432	63	29	alteration	alteration	NOUN
amwa-432	63	30	,	,	PUNCT
amwa-432	63	31	metabolic	metabolic	NOUN
amwa-432	63	32	acidosis	acidosis	NOUN
amwa-432	63	33	,	,	PUNCT
amwa-432	63	34	and	and	CCONJ
amwa-432	63	35	nephrolithiasis	nephrolithiasis	NOUN
amwa-432	63	36	.	.	PUNCT
amwa-432	64	1	topiramate	topiramate	NOUN
amwa-432	64	2	has	have	VERB
amwa-432	64	3	teratogenic	teratogenic	ADJ
amwa-432	64	4	effects	effect	NOUN
amwa-432	64	5	and	and	CCONJ
amwa-432	64	6	can	can	AUX
amwa-432	64	7	cause	cause	VERB
amwa-432	64	8	fetal	fetal	ADJ
amwa-432	64	9	harm	harm	NOUN
amwa-432	64	10	.	.	PUNCT
amwa-432	65	1	as	as	ADP
amwa-432	65	2	an	an	DET
amwa-432	65	3	alternative	alternative	NOUN
amwa-432	65	4	,	,	PUNCT
amwa-432	65	5	the	the	DET
amwa-432	65	6	fda	fda	PROPN
amwa-432	65	7	approved	approve	VERB
amwa-432	65	8	naloxone	naloxone	NOUN
amwa-432	65	9	with	with	ADP
amwa-432	65	10	bupropion	bupropion	NOUN
amwa-432	65	11	(	(	PUNCT
amwa-432	65	12	nal	nal	PROPN
amwa-432	65	13	/	/	SYM
amwa-432	65	14	bu	bu	NOUN
amwa-432	65	15	)	)	PUNCT
amwa-432	65	16	for	for	ADP
amwa-432	65	17	use	use	NOUN
amwa-432	65	18	in	in	ADP
amwa-432	65	19	adults	adult	NOUN
amwa-432	65	20	.	.	PUNCT
amwa-432	66	1	nal	nal	PROPN
amwa-432	66	2	/	/	SYM
amwa-432	66	3	bu	bu	PROPN
amwa-432	66	4	may	may	AUX
amwa-432	66	5	elevate	elevate	VERB
amwa-432	66	6	blood	blood	NOUN
amwa-432	66	7	pressure	pressure	NOUN
amwa-432	66	8	and	and	CCONJ
amwa-432	66	9	increase	increase	VERB
amwa-432	66	10	risk	risk	NOUN
amwa-432	66	11	of	of	ADP
amwa-432	66	12	hepatotoxicity	hepatotoxicity	NOUN
amwa-432	66	13	or	or	CCONJ
amwa-432	66	14	suicidal	suicidal	ADJ
amwa-432	66	15	ideation	ideation	NOUN
amwa-432	66	16	.	.	PUNCT
amwa-432	67	1	comparing	compare	VERB
amwa-432	67	2	long	long	ADJ
amwa-432	67	3	-	-	PUNCT
amwa-432	67	4	term	term	NOUN
amwa-432	67	5	therapies	therapy	NOUN
amwa-432	67	6	for	for	ADP
amwa-432	67	7	weight	weight	NOUN
amwa-432	67	8	loss	loss	NOUN
amwa-432	67	9	one	one	NUM
amwa-432	67	10	review	review	NOUN
amwa-432	67	11	of	of	ADP
amwa-432	67	12	28	28	NUM
amwa-432	67	13	random	random	ADJ
amwa-432	67	14	controlled	control	VERB
amwa-432	67	15	trials	trial	NOUN
amwa-432	67	16	included	include	VERB
amwa-432	67	17	orlistat	orlistat	NOUN
amwa-432	67	18	,	,	PUNCT
amwa-432	67	19	phen	phen	PROPN
amwa-432	67	20	/	/	SYM
amwa-432	67	21	top	top	ADJ
amwa-432	67	22	,	,	PUNCT
amwa-432	67	23	nal	nal	NOUN
amwa-432	67	24	/	/	SYM
amwa-432	67	25	bu	bu	NOUN
amwa-432	67	26	,	,	PUNCT
amwa-432	67	27	and	and	CCONJ
amwa-432	67	28	liraglutide	liraglutide	PROPN
amwa-432	67	29	.	.	PUNCT
amwa-432	68	1	interestingly	interestingly	ADV
amwa-432	68	2	,	,	PUNCT
amwa-432	68	3	the	the	DET
amwa-432	68	4	study	study	NOUN
amwa-432	68	5	showed	show	VERB
amwa-432	68	6	that	that	SCONJ
amwa-432	68	7	clinical	clinical	ADJ
amwa-432	68	8	trial	trial	NOUN
amwa-432	68	9	participants	participant	NOUN
amwa-432	68	10	reported	report	VERB
amwa-432	68	11	the	the	DET
amwa-432	68	12	most	most	ADJ
amwa-432	68	13	success	success	NOUN
amwa-432	68	14	using	use	VERB
amwa-432	68	15	phen	phen	PROPN
amwa-432	68	16	/	/	SYM
amwa-432	68	17	top	top	NOUN
amwa-432	68	18	(	(	PUNCT
amwa-432	68	19	75	75	NUM
amwa-432	68	20	%	%	NOUN
amwa-432	68	21	efficacy	efficacy	NOUN
amwa-432	68	22	)	)	PUNCT
amwa-432	68	23	compared	compare	VERB
amwa-432	68	24	with	with	ADP
amwa-432	68	25	orlistat	orlistat	PROPN
amwa-432	68	26	(	(	PUNCT
amwa-432	68	27	44	44	NUM
amwa-432	68	28	%	%	NOUN
amwa-432	68	29	)	)	PUNCT
amwa-432	68	30	,	,	PUNCT
amwa-432	68	31	nal	nal	PROPN
amwa-432	68	32	/	/	SYM
amwa-432	68	33	bu	bu	PROPN
amwa-432	68	34	(	(	PUNCT
amwa-432	68	35	55	55	NUM
amwa-432	68	36	%	%	NOUN
amwa-432	68	37	)	)	PUNCT
amwa-432	68	38	,	,	PUNCT
amwa-432	68	39	or	or	CCONJ
amwa-432	68	40	liraglutide	liraglutide	NOUN
amwa-432	68	41	(	(	PUNCT
amwa-432	68	42	63%).18	63%).18	NUM
amwa-432	68	43	more	more	ADV
amwa-432	68	44	recently	recently	ADV
amwa-432	68	45	,	,	PUNCT
amwa-432	68	46	a	a	DET
amwa-432	68	47	systematic	systematic	ADJ
amwa-432	68	48	review	review	NOUN
amwa-432	68	49	and	and	CCONJ
amwa-432	68	50	meta	meta	ADJ
amwa-432	68	51	-	-	PUNCT
amwa-432	68	52	analysis	analysis	NOUN
amwa-432	68	53	was	be	AUX
amwa-432	68	54	figure	figure	NOUN
amwa-432	68	55	3	3	NUM
amwa-432	68	56	.	.	PUNCT
amwa-432	69	1	us	we	PRON
amwa-432	69	2	racial	racial	ADJ
amwa-432	69	3	and	and	CCONJ
amwa-432	69	4	ethnic	ethnic	ADJ
amwa-432	69	5	differences	difference	NOUN
amwa-432	69	6	in	in	ADP
amwa-432	69	7	the	the	DET
amwa-432	69	8	prevalence	prevalence	NOUN
amwa-432	69	9	of	of	ADP
amwa-432	69	10	adults	adult	NOUN
amwa-432	69	11	with	with	ADP
amwa-432	69	12	bmi	bmi	PROPN
amwa-432	69	13	≥30	≥30	PROPN
amwa-432	69	14	and	and	CCONJ
amwa-432	69	15	youth	youth	NOUN
amwa-432	69	16	greater	great	ADJ
amwa-432	69	17	than	than	ADP
amwa-432	69	18	the	the	DET
amwa-432	69	19	ninety	ninety	NUM
amwa-432	69	20	-	-	PUNCT
amwa-432	69	21	fifth	fifth	ADJ
amwa-432	69	22	percentile.11,12	percentile.11,12	NOUN
amwa-432	69	23	adults	adult	NOUN
amwa-432	69	24	are	be	AUX
amwa-432	69	25	defined	define	VERB
amwa-432	69	26	as	as	ADP
amwa-432	69	27	age	age	NOUN
amwa-432	69	28	≥20	≥20	NOUN
amwa-432	69	29	years	year	NOUN
amwa-432	69	30	,	,	PUNCT
amwa-432	69	31	and	and	CCONJ
amwa-432	69	32	youth	youth	NOUN
amwa-432	69	33	are	be	AUX
amwa-432	69	34	defined	define	VERB
amwa-432	69	35	as	as	ADP
amwa-432	69	36	age	age	NOUN
amwa-432	69	37	2	2	NUM
amwa-432	69	38	-	-	SYM
amwa-432	69	39	19	19	NUM
amwa-432	69	40	years	year	NOUN
amwa-432	69	41	.	.	PUNCT
amwa-432	70	1	bmi	bmi	PROPN
amwa-432	70	2	,	,	PUNCT
amwa-432	70	3	body	body	NOUN
amwa-432	70	4	mass	mass	PROPN
amwa-432	70	5	index	index	NOUN
amwa-432	70	6	.	.	PUNCT
amwa-432	71	1	9	9	NUM
amwa-432	71	2	%	%	NOUN
amwa-432	71	3	25	25	NUM
amwa-432	71	4	%	%	NOUN
amwa-432	71	5	26	26	NUM
amwa-432	71	6	%	%	NOUN
amwa-432	71	7	17%17	17%17	NUM
amwa-432	71	8	%	%	NOUN
amwa-432	71	9	50	50	NUM
amwa-432	71	10	%	%	NOUN
amwa-432	71	11	45	45	NUM
amwa-432	71	12	%	%	NOUN
amwa-432	71	13	42	42	NUM
amwa-432	71	14	%	%	NOUN
amwa-432	71	15	0	0	NUM
amwa-432	71	16	%	%	NOUN
amwa-432	71	17	10	10	NUM
amwa-432	71	18	%	%	NOUN
amwa-432	71	19	20	20	NUM
amwa-432	71	20	%	%	NOUN
amwa-432	71	21	30	30	NUM
amwa-432	71	22	%	%	NOUN
amwa-432	71	23	40	40	NUM
amwa-432	71	24	%	%	NOUN
amwa-432	71	25	50	50	NUM
amwa-432	71	26	%	%	NOUN
amwa-432	71	27	60	60	NUM
amwa-432	71	28	%	%	NOUN
amwa-432	71	29	asian	asian	ADJ
amwa-432	71	30	black	black	ADJ
amwa-432	71	31	hispanic	hispanic	ADJ
amwa-432	71	32	white	white	ADJ
amwa-432	71	33	youth	youth	NOUN
amwa-432	71	34	adults	adult	NOUN
amwa-432	71	35	http://www.amwajournal.org	http://www.amwajournal.org	X
amwa-432	71	36	amwajournal.org	amwajournal.org	X
amwa-432	71	37	38incretin	38incretin	NUM
amwa-432	71	38	drug	drug	NOUN
amwa-432	71	39	revolution	revolution	NOUN
amwa-432	71	40	:	:	PUNCT
amwa-432	71	41	the	the	DET
amwa-432	71	42	challenges	challenge	NOUN
amwa-432	71	43	of	of	ADP
amwa-432	71	44	hope	hope	NOUN
amwa-432	71	45	performed	perform	VERB
amwa-432	71	46	using	use	VERB
amwa-432	71	47	53	53	NUM
amwa-432	71	48	clinical	clinical	ADJ
amwa-432	71	49	trials	trial	NOUN
amwa-432	71	50	for	for	ADP
amwa-432	71	51	obesity	obesity	NOUN
amwa-432	71	52	drugs	drug	NOUN
amwa-432	71	53	.	.	PUNCT
amwa-432	72	1	the	the	DET
amwa-432	72	2	findings	finding	NOUN
amwa-432	72	3	showed	show	VERB
amwa-432	72	4	that	that	SCONJ
amwa-432	72	5	tirzepatide	tirzepatide	NOUN
amwa-432	72	6	effectively	effectively	ADV
amwa-432	72	7	reduced	reduce	VERB
amwa-432	72	8	waist	waist	NOUN
amwa-432	72	9	circumference	circumference	NOUN
amwa-432	72	10	by	by	ADP
amwa-432	72	11	6.77	6.77	NUM
amwa-432	72	12	cm	cm	NOUN
amwa-432	72	13	compared	compare	VERB
amwa-432	72	14	with	with	ADP
amwa-432	72	15	semaglutide	semaglutide	NOUN
amwa-432	72	16	(	(	PUNCT
amwa-432	72	17	3.74	3.74	NUM
amwa-432	72	18	cm	cm	NOUN
amwa-432	72	19	)	)	PUNCT
amwa-432	72	20	and	and	CCONJ
amwa-432	72	21	liraglutide	liraglutide	VERB
amwa-432	72	22	(	(	PUNCT
amwa-432	72	23	2.30	2.30	NUM
amwa-432	72	24	cm).19	cm).19	NOUN
amwa-432	72	25	in	in	ADP
amwa-432	72	26	a	a	DET
amwa-432	72	27	subanalysis	subanalysis	ADJ
amwa-432	72	28	,	,	PUNCT
amwa-432	72	29	semaglutide	semaglutide	ADJ
amwa-432	72	30	was	be	AUX
amwa-432	72	31	the	the	DET
amwa-432	72	32	only	only	ADJ
amwa-432	72	33	incretin	incretin	NOUN
amwa-432	72	34	drug	drug	NOUN
amwa-432	72	35	to	to	PART
amwa-432	72	36	effectively	effectively	ADV
amwa-432	72	37	reduce	reduce	VERB
amwa-432	72	38	low	low	ADJ
amwa-432	72	39	-	-	PUNCT
amwa-432	72	40	density	density	NOUN
amwa-432	72	41	lipoprotein	lipoprotein	ADJ
amwa-432	72	42	and	and	CCONJ
amwa-432	72	43	total	total	ADJ
amwa-432	72	44	cholesterol	cholesterol	NOUN
amwa-432	72	45	yet	yet	ADV
amwa-432	72	46	showed	show	VERB
amwa-432	72	47	the	the	DET
amwa-432	72	48	highest	high	ADJ
amwa-432	72	49	discontinuation	discontinuation	NOUN
amwa-432	72	50	rate	rate	NOUN
amwa-432	72	51	because	because	SCONJ
amwa-432	72	52	of	of	ADP
amwa-432	72	53	gastrointestinal	gastrointestinal	ADJ
amwa-432	72	54	(	(	PUNCT
amwa-432	72	55	gi	gi	NOUN
amwa-432	72	56	)	)	PUNCT
amwa-432	72	57	events	event	NOUN
amwa-432	72	58	.	.	PUNCT
amwa-432	73	1	in	in	ADP
amwa-432	73	2	fact	fact	NOUN
amwa-432	73	3	,	,	PUNCT
amwa-432	73	4	safety	safety	NOUN
amwa-432	73	5	concerns	concern	NOUN
amwa-432	73	6	for	for	ADP
amwa-432	73	7	the	the	DET
amwa-432	73	8	incretin	incretin	ADJ
amwa-432	73	9	drugs	drug	NOUN
amwa-432	73	10	are	be	AUX
amwa-432	73	11	warranted	warrant	VERB
amwa-432	73	12	at	at	ADP
amwa-432	73	13	higher	high	ADJ
amwa-432	73	14	doses	dose	NOUN
amwa-432	73	15	.	.	PUNCT
amwa-432	74	1	except	except	SCONJ
amwa-432	74	2	for	for	ADP
amwa-432	74	3	orlistat	orlistat	NOUN
amwa-432	74	4	,	,	PUNCT
amwa-432	74	5	a	a	DET
amwa-432	74	6	local	local	ADJ
amwa-432	74	7	-	-	PUNCT
amwa-432	74	8	acting	act	VERB
amwa-432	74	9	lipase	lipase	NOUN
amwa-432	74	10	inhibitor	inhibitor	NOUN
amwa-432	74	11	,	,	PUNCT
amwa-432	74	12	all	all	DET
amwa-432	74	13	obesity	obesity	NOUN
amwa-432	74	14	therapies	therapy	NOUN
amwa-432	74	15	act	act	VERB
amwa-432	74	16	by	by	ADP
amwa-432	74	17	increasing	increase	VERB
amwa-432	74	18	norepinephrine	norepinephrine	NOUN
amwa-432	74	19	to	to	PART
amwa-432	74	20	decrease	decrease	VERB
amwa-432	74	21	appetite	appetite	NOUN
amwa-432	74	22	.	.	PUNCT
amwa-432	75	1	understanding	understand	VERB
amwa-432	75	2	neuroendocrine	neuroendocrine	NOUN
amwa-432	75	3	signals	signal	NOUN
amwa-432	75	4	that	that	PRON
amwa-432	75	5	regulate	regulate	VERB
amwa-432	75	6	hunger	hunger	NOUN
amwa-432	75	7	helps	help	VERB
amwa-432	75	8	elucidate	elucidate	VERB
amwa-432	75	9	related	related	ADJ
amwa-432	75	10	health	health	NOUN
amwa-432	75	11	risks	risk	NOUN
amwa-432	75	12	for	for	ADP
amwa-432	75	13	these	these	DET
amwa-432	75	14	drugs	drug	NOUN
amwa-432	75	15	.	.	PUNCT
amwa-432	76	1	pharmacotherapies	pharmacotherapie	NOUN
amwa-432	76	2	:	:	PUNCT
amwa-432	76	3	balancing	balance	VERB
amwa-432	76	4	appetite	appetite	NOUN
amwa-432	76	5	two	two	NUM
amwa-432	76	6	opposing	oppose	VERB
amwa-432	76	7	types	type	NOUN
amwa-432	76	8	of	of	ADP
amwa-432	76	9	neurons	neuron	NOUN
amwa-432	76	10	in	in	ADP
amwa-432	76	11	the	the	DET
amwa-432	76	12	hypothalamus	hypothalamus	PROPN
amwa-432	76	13	balance	balance	NOUN
amwa-432	76	14	energy	energy	NOUN
amwa-432	76	15	intake	intake	NOUN
amwa-432	76	16	to	to	PART
amwa-432	76	17	control	control	VERB
amwa-432	76	18	appetite	appetite	NOUN
amwa-432	76	19	.	.	PUNCT
amwa-432	77	1	the	the	DET
amwa-432	77	2	agouti	agouti	NOUN
amwa-432	77	3	-	-	PUNCT
amwa-432	77	4	related	relate	VERB
amwa-432	77	5	peptide/	peptide/	NUM
amwa-432	77	6	neuropeptide	neuropeptide	NOUN
amwa-432	77	7	y	y	NOUN
amwa-432	77	8	(	(	PUNCT
amwa-432	77	9	agrp	agrp	PROPN
amwa-432	77	10	/	/	SYM
amwa-432	77	11	npy	npy	PROPN
amwa-432	77	12	)	)	PUNCT
amwa-432	77	13	neurons	neuron	NOUN
amwa-432	77	14	constantly	constantly	ADV
amwa-432	77	15	co	co	VERB
amwa-432	77	16	-	-	VERB
amwa-432	77	17	release	release	VERB
amwa-432	77	18	γ	γ	ADJ
amwa-432	77	19	-	-	ADJ
amwa-432	77	20	aminobutyric	aminobutyric	ADJ
amwa-432	77	21	acid	acid	NOUN
amwa-432	77	22	(	(	PUNCT
amwa-432	77	23	gaba	gaba	PROPN
amwa-432	77	24	)	)	PUNCT
amwa-432	77	25	and	and	CCONJ
amwa-432	77	26	npy	npy	PROPN
amwa-432	77	27	peptides	peptide	NOUN
amwa-432	77	28	to	to	PART
amwa-432	77	29	lower	lower	VERB
amwa-432	77	30	sympathetic	sympathetic	ADJ
amwa-432	77	31	activity	activity	NOUN
amwa-432	77	32	,	,	PUNCT
amwa-432	77	33	turning	turn	VERB
amwa-432	77	34	on	on	ADP
amwa-432	77	35	appetite	appetite	NOUN
amwa-432	77	36	(	(	PUNCT
amwa-432	77	37	figure	figure	NOUN
amwa-432	77	38	4	4	NUM
amwa-432	77	39	)	)	PUNCT
amwa-432	77	40	.	.	PUNCT
amwa-432	78	1	once	once	SCONJ
amwa-432	78	2	food	food	NOUN
amwa-432	78	3	enters	enter	VERB
amwa-432	78	4	the	the	DET
amwa-432	78	5	stomach	stomach	NOUN
amwa-432	78	6	,	,	PUNCT
amwa-432	78	7	the	the	DET
amwa-432	78	8	gut	gut	NOUN
amwa-432	78	9	releases	release	VERB
amwa-432	78	10	incretins	incretin	NOUN
amwa-432	78	11	and	and	CCONJ
amwa-432	78	12	adipose	adipose	NOUN
amwa-432	78	13	releases	release	NOUN
amwa-432	78	14	leptin	leptin	VERB
amwa-432	78	15	,	,	PUNCT
amwa-432	78	16	slowing	slow	VERB
amwa-432	78	17	intestinal	intestinal	ADJ
amwa-432	78	18	motility	motility	NOUN
amwa-432	78	19	to	to	PART
amwa-432	78	20	prolong	prolong	VERB
amwa-432	78	21	satiety.20	satiety.20	PROPN
amwa-432	78	22	the	the	DET
amwa-432	78	23	opposing	opposing	ADJ
amwa-432	78	24	pro	pro	ADJ
amwa-432	78	25	-	-	ADJ
amwa-432	78	26	opiomelanocortin	opiomelanocortin	ADJ
amwa-432	78	27	/	/	SYM
amwa-432	78	28	cocaine	cocaine	NOUN
amwa-432	78	29	amphetamine	amphetamine	NOUN
amwa-432	78	30	-	-	PUNCT
amwa-432	78	31	related	relate	VERB
amwa-432	78	32	transcript	transcript	NOUN
amwa-432	78	33	(	(	PUNCT
amwa-432	78	34	pomc	pomc	NOUN
amwa-432	78	35	/	/	SYM
amwa-432	78	36	cart	cart	NOUN
amwa-432	78	37	)	)	PUNCT
amwa-432	78	38	neurons	neuron	NOUN
amwa-432	78	39	receive	receive	VERB
amwa-432	78	40	these	these	DET
amwa-432	78	41	gut	gut	NOUN
amwa-432	78	42	signals	signal	NOUN
amwa-432	78	43	to	to	PART
amwa-432	78	44	enhance	enhance	VERB
amwa-432	78	45	sympathetic	sympathetic	ADJ
amwa-432	78	46	release	release	NOUN
amwa-432	78	47	of	of	ADP
amwa-432	78	48	norepinephrine	norepinephrine	NOUN
amwa-432	78	49	,	,	PUNCT
amwa-432	78	50	turning	turn	VERB
amwa-432	78	51	off	off	ADP
amwa-432	78	52	appetite	appetite	NOUN
amwa-432	78	53	.	.	PUNCT
amwa-432	79	1	many	many	ADJ
amwa-432	79	2	pharmacotherapies	pharmacotherapie	NOUN
amwa-432	79	3	for	for	ADP
amwa-432	79	4	weight	weight	NOUN
amwa-432	79	5	loss	loss	NOUN
amwa-432	79	6	increase	increase	NOUN
amwa-432	79	7	sympathetic	sympathetic	ADJ
amwa-432	79	8	activity	activity	NOUN
amwa-432	79	9	and	and	CCONJ
amwa-432	79	10	norepinephrine	norepinephrine	NOUN
amwa-432	79	11	to	to	PART
amwa-432	79	12	turn	turn	VERB
amwa-432	79	13	off	off	ADP
amwa-432	79	14	appetite	appetite	NOUN
amwa-432	79	15	.	.	PUNCT
amwa-432	80	1	gaba	gaba	NOUN
amwa-432	80	2	-	-	PUNCT
amwa-432	80	3	modulating	modulate	VERB
amwa-432	80	4	drugs	drug	NOUN
amwa-432	80	5	like	like	ADP
amwa-432	80	6	topiramate	topiramate	NOUN
amwa-432	80	7	increase	increase	NOUN
amwa-432	80	8	the	the	DET
amwa-432	80	9	brain	brain	NOUN
amwa-432	80	10	’s	’s	PART
amwa-432	80	11	sympathetic	sympathetic	ADJ
amwa-432	80	12	activity	activity	NOUN
amwa-432	80	13	to	to	PART
amwa-432	80	14	lower	low	ADJ
amwa-432	80	15	appetite	appetite	NOUN
amwa-432	80	16	.	.	PUNCT
amwa-432	81	1	but	but	CCONJ
amwa-432	81	2	sympathomimetic	sympathomimetic	ADJ
amwa-432	81	3	drugs	drug	NOUN
amwa-432	81	4	like	like	ADP
amwa-432	81	5	phentermine	phentermine	NOUN
amwa-432	81	6	stimulate	stimulate	VERB
amwa-432	81	7	sympathetic	sympathetic	ADJ
amwa-432	81	8	release	release	NOUN
amwa-432	81	9	of	of	ADP
amwa-432	81	10	norepinephrine	norepinephrine	NOUN
amwa-432	81	11	to	to	PART
amwa-432	81	12	lower	lower	VERB
amwa-432	81	13	appetite.16	appetite.16	PROPN
amwa-432	81	14	bupropion	bupropion	NOUN
amwa-432	81	15	and	and	CCONJ
amwa-432	81	16	naltrexone	naltrexone	PROPN
amwa-432	81	17	also	also	ADV
amwa-432	81	18	stimulate	stimulate	VERB
amwa-432	81	19	sympathetic	sympathetic	ADJ
amwa-432	81	20	activity	activity	NOUN
amwa-432	81	21	but	but	CCONJ
amwa-432	81	22	directly	directly	ADV
amwa-432	81	23	activate	activate	VERB
amwa-432	81	24	pomc	pomc	NOUN
amwa-432	81	25	/	/	SYM
amwa-432	81	26	cart	cart	NOUN
amwa-432	81	27	neurons	neuron	NOUN
amwa-432	81	28	to	to	PART
amwa-432	81	29	diminish	diminish	VERB
amwa-432	81	30	hunger	hunger	NOUN
amwa-432	81	31	.	.	PUNCT
amwa-432	82	1	interestingly	interestingly	ADV
amwa-432	82	2	,	,	PUNCT
amwa-432	82	3	naltrexone	naltrexone	PROPN
amwa-432	82	4	acts	act	VERB
amwa-432	82	5	as	as	ADP
amwa-432	82	6	a	a	DET
amwa-432	82	7	long	long	ADV
amwa-432	82	8	-	-	PUNCT
amwa-432	82	9	acting	act	VERB
amwa-432	82	10	opioid	opioid	ADJ
amwa-432	82	11	antagonist	antagonist	NOUN
amwa-432	82	12	to	to	PART
amwa-432	82	13	change	change	VERB
amwa-432	82	14	the	the	DET
amwa-432	82	15	brain	brain	NOUN
amwa-432	82	16	’s	’s	PART
amwa-432	82	17	response	response	NOUN
amwa-432	82	18	to	to	ADP
amwa-432	82	19	food	food	NOUN
amwa-432	82	20	by	by	ADP
amwa-432	82	21	altering	alter	VERB
amwa-432	82	22	the	the	DET
amwa-432	82	23	dopamine	dopamine	NOUN
amwa-432	82	24	-	-	PUNCT
amwa-432	82	25	reward	reward	NOUN
amwa-432	82	26	system.16	system.16	PROPN
amwa-432	82	27	incretin	incretin	NOUN
amwa-432	82	28	drugs	drug	NOUN
amwa-432	82	29	mimic	mimic	VERB
amwa-432	82	30	the	the	DET
amwa-432	82	31	actions	action	NOUN
amwa-432	82	32	of	of	ADP
amwa-432	82	33	glp-1	glp-1	NOUN
amwa-432	82	34	and	and	CCONJ
amwa-432	82	35	gip	gip	NOUN
amwa-432	82	36	that	that	PRON
amwa-432	82	37	stimulate	stimulate	VERB
amwa-432	82	38	glucose	glucose	NOUN
amwa-432	82	39	-	-	PUNCT
amwa-432	82	40	dependent	dependent	ADJ
amwa-432	82	41	increases	increase	NOUN
amwa-432	82	42	in	in	ADP
amwa-432	82	43	insulin	insulin	NOUN
amwa-432	82	44	,	,	PUNCT
amwa-432	82	45	slow	slow	ADJ
amwa-432	82	46	gastric	gastric	ADJ
amwa-432	82	47	emptying	emptying	NOUN
amwa-432	82	48	,	,	PUNCT
amwa-432	82	49	and	and	CCONJ
amwa-432	82	50	extend	extend	VERB
amwa-432	82	51	satiety	satiety	NOUN
amwa-432	82	52	to	to	ADP
amwa-432	82	53	lower	low	ADJ
amwa-432	82	54	appetite	appetite	NOUN
amwa-432	82	55	.	.	PUNCT
amwa-432	83	1	although	although	SCONJ
amwa-432	83	2	glp-1	glp-1	VERB
amwa-432	83	3	ras	ras	X
amwa-432	83	4	suppress	suppress	ADJ
amwa-432	83	5	pancreatic	pancreatic	NOUN
amwa-432	83	6	-	-	PUNCT
amwa-432	83	7	glucose	glucose	NOUN
amwa-432	83	8	-	-	PUNCT
amwa-432	83	9	dependent	dependent	ADJ
amwa-432	83	10	release	release	NOUN
amwa-432	83	11	of	of	ADP
amwa-432	83	12	glucagon	glucagon	NOUN
amwa-432	83	13	,	,	PUNCT
amwa-432	83	14	gip	gip	NOUN
amwa-432	83	15	receptor	receptor	NOUN
amwa-432	83	16	agonists	agonist	NOUN
amwa-432	83	17	stimulate	stimulate	VERB
amwa-432	83	18	it.15	it.15	PROPN
amwa-432	83	19	but	but	CCONJ
amwa-432	83	20	the	the	DET
amwa-432	83	21	low	low	ADJ
amwa-432	83	22	permeability	permeability	NOUN
amwa-432	83	23	of	of	ADP
amwa-432	83	24	incretin	incretin	ADJ
amwa-432	83	25	drugs	drug	NOUN
amwa-432	83	26	likely	likely	ADV
amwa-432	83	27	prevent	prevent	VERB
amwa-432	83	28	access	access	NOUN
amwa-432	83	29	through	through	ADP
amwa-432	83	30	the	the	DET
amwa-432	83	31	blood	blood	NOUN
amwa-432	83	32	-	-	PUNCT
amwa-432	83	33	brain	brain	NOUN
amwa-432	83	34	barrier	barrier	NOUN
amwa-432	83	35	.	.	PUNCT
amwa-432	84	1	supporting	support	VERB
amwa-432	84	2	this	this	PRON
amwa-432	84	3	,	,	PUNCT
amwa-432	84	4	studies	study	NOUN
amwa-432	84	5	indicate	indicate	VERB
amwa-432	84	6	that	that	SCONJ
amwa-432	84	7	incretin	incretin	NOUN
amwa-432	84	8	drugs	drug	NOUN
amwa-432	84	9	signal	signal	VERB
amwa-432	84	10	the	the	DET
amwa-432	84	11	hypothalamus	hypothalamus	NOUN
amwa-432	84	12	via	via	ADP
amwa-432	84	13	the	the	DET
amwa-432	84	14	dorsal	dorsal	NOUN
amwa-432	84	15	vagal	vagal	ADJ
amwa-432	84	16	complex	complex	NOUN
amwa-432	84	17	,	,	PUNCT
amwa-432	84	18	which	which	PRON
amwa-432	84	19	may	may	AUX
amwa-432	84	20	explain	explain	VERB
amwa-432	84	21	the	the	DET
amwa-432	84	22	negative	negative	ADJ
amwa-432	84	23	side	side	NOUN
amwa-432	84	24	effects	effect	NOUN
amwa-432	84	25	like	like	ADP
amwa-432	84	26	nausea	nausea	NOUN
amwa-432	84	27	and	and	CCONJ
amwa-432	84	28	vomiting.15	vomiting.15	NOUN
amwa-432	84	29	table	table	NOUN
amwa-432	84	30	1	1	NUM
amwa-432	84	31	.	.	PUNCT
amwa-432	84	32	fda	fda	PROPN
amwa-432	84	33	-	-	PUNCT
amwa-432	84	34	approved	approve	VERB
amwa-432	84	35	drugs	drug	NOUN
amwa-432	84	36	for	for	ADP
amwa-432	84	37	clinical	clinical	ADJ
amwa-432	84	38	obesity	obesity	NOUN
amwa-432	84	39	treatment11,16,17	treatment11,16,17	ADJ
amwa-432	84	40	drug	drug	NOUN
amwa-432	84	41	name	name	NOUN
amwa-432	84	42	brand	brand	NOUN
amwa-432	84	43	name	name	NOUN
amwa-432	84	44	usage	usage	NOUN
amwa-432	84	45	,	,	PUNCT
amwa-432	84	46	y	y	PROPN
amwa-432	84	47	dosage	dosage	VERB
amwa-432	84	48	clinical	clinical	ADJ
amwa-432	84	49	trial	trial	NOUN
amwa-432	84	50	demographics	demographic	NOUN
amwa-432	84	51	orlistat	orlistat	PROPN
amwa-432	84	52	alli	alli	PROPN
amwa-432	84	53	(	(	PUNCT
amwa-432	84	54	otc	otc	PROPN
amwa-432	84	55	)	)	PUNCT
amwa-432	84	56	;	;	PUNCT
amwa-432	84	57	xenical	xenical	PROPN
amwa-432	84	58	≥12	≥12	ADP
amwa-432	84	59	capsule	capsule	PROPN
amwa-432	84	60	:	:	PUNCT
amwa-432	84	61	alli	alli	PROPN
amwa-432	84	62	,	,	PUNCT
amwa-432	84	63	60	60	NUM
amwa-432	84	64	mg	mg	NUM
amwa-432	84	65	;	;	PUNCT
amwa-432	84	66	xenical	xenical	ADJ
amwa-432	84	67	,	,	PUNCT
amwa-432	84	68	120	120	NUM
amwa-432	84	69	mg	mg	PROPN
amwa-432	84	70	xendos	xendos	PROPN
amwa-432	84	71	55	55	NUM
amwa-432	84	72	%	%	NOUN
amwa-432	84	73	women	woman	NOUN
amwa-432	84	74	;	;	PUNCT
amwa-432	84	75	mean	mean	VERB
amwa-432	84	76	age	age	NOUN
amwa-432	84	77	,	,	PUNCT
amwa-432	84	78	43	43	NUM
amwa-432	84	79	y	y	NOUN
amwa-432	84	80	;	;	PUNCT
amwa-432	84	81	average	average	ADJ
amwa-432	84	82	bmi	bmi	NOUN
amwa-432	84	83	,	,	PUNCT
amwa-432	84	84	37	37	NUM
amwa-432	84	85	;	;	PUNCT
amwa-432	84	86	71	71	NUM
amwa-432	84	87	%	%	NOUN
amwa-432	84	88	white	white	ADJ
amwa-432	84	89	adults	adult	NOUN
amwa-432	84	90	phentermine	phentermine	NOUN
amwa-432	84	91	with	with	ADP
amwa-432	84	92	topiramate	topiramate	ADJ
amwa-432	84	93	qsymia	qsymia	NOUN
amwa-432	84	94	≥12	≥12	ADP
amwa-432	84	95	phentermine	phentermine	ADV
amwa-432	84	96	/	/	SYM
amwa-432	84	97	topiramate	topiramate	NOUN
amwa-432	84	98	:	:	PUNCT
amwa-432	84	99	3.75	3.75	NUM
amwa-432	84	100	mg/23	mg/23	PROPN
amwa-432	84	101	mg	mg	PROPN
amwa-432	84	102	;	;	PUNCT
amwa-432	84	103	7.5	7.5	NUM
amwa-432	84	104	mg/46	mg/46	PROPN
amwa-432	84	105	mg	mg	NOUN
amwa-432	84	106	;	;	PUNCT
amwa-432	85	1	11.25	11.25	NUM
amwa-432	85	2	mg/69	mg/69	PROPN
amwa-432	85	3	mg	mg	PROPN
amwa-432	85	4	;	;	PUNCT
amwa-432	85	5	15	15	NUM
amwa-432	85	6	mg/92	mg/92	PROPN
amwa-432	85	7	mg	mg	PROPN
amwa-432	85	8	equip	equip	NOUN
amwa-432	85	9	83	83	NUM
amwa-432	85	10	%	%	NOUN
amwa-432	85	11	women	woman	NOUN
amwa-432	85	12	;	;	PUNCT
amwa-432	85	13	mean	mean	VERB
amwa-432	85	14	age	age	NOUN
amwa-432	85	15	,	,	PUNCT
amwa-432	85	16	43	43	NUM
amwa-432	85	17	y	y	NOUN
amwa-432	85	18	;	;	PUNCT
amwa-432	85	19	average	average	ADJ
amwa-432	85	20	bmi,42	bmi,42	PROPN
amwa-432	85	21	;	;	PUNCT
amwa-432	85	22	80	80	NUM
amwa-432	85	23	%	%	NOUN
amwa-432	85	24	white	white	ADJ
amwa-432	85	25	adults	adult	NOUN
amwa-432	85	26	conquer	conquer	VERB
amwa-432	85	27	70	70	NUM
amwa-432	85	28	%	%	NOUN
amwa-432	85	29	women	woman	NOUN
amwa-432	85	30	;	;	PUNCT
amwa-432	85	31	mean	mean	VERB
amwa-432	85	32	age	age	NOUN
amwa-432	85	33	,	,	PUNCT
amwa-432	85	34	51	51	NUM
amwa-432	85	35	y	y	NOUN
amwa-432	85	36	;	;	PUNCT
amwa-432	85	37	average	average	ADJ
amwa-432	85	38	bmi	bmi	NOUN
amwa-432	85	39	,	,	PUNCT
amwa-432	85	40	36	36	NUM
amwa-432	85	41	;	;	PUNCT
amwa-432	85	42	85	85	NUM
amwa-432	85	43	%	%	NOUN
amwa-432	85	44	white	white	ADJ
amwa-432	85	45	adults	adult	NOUN
amwa-432	85	46	naltrexone	naltrexone	PROPN
amwa-432	85	47	with	with	ADP
amwa-432	85	48	bupropion	bupropion	NOUN
amwa-432	85	49	contrave	contrave	PROPN
amwa-432	85	50	(	(	PUNCT
amwa-432	85	51	us	us	PROPN
amwa-432	85	52	)	)	PUNCT
amwa-432	85	53	;	;	PUNCT
amwa-432	85	54	mysimba	mysimba	NOUN
amwa-432	85	55	(	(	PUNCT
amwa-432	85	56	eu	eu	PROPN
amwa-432	85	57	)	)	PUNCT
amwa-432	85	58	≥18	≥18	PROPN
amwa-432	85	59	naltrexone	naltrexone	PROPN
amwa-432	85	60	/	/	SYM
amwa-432	85	61	bupropion	bupropion	NOUN
amwa-432	85	62	:	:	PUNCT
amwa-432	85	63	8mg/90	8mg/90	NUM
amwa-432	85	64	mg	mg	PROPN
amwa-432	85	65	cor	cor	PROPN
amwa-432	85	66	-	-	PROPN
amwa-432	85	67	i	i	PRON
amwa-432	85	68	85	85	NUM
amwa-432	85	69	%	%	NOUN
amwa-432	85	70	women	woman	NOUN
amwa-432	85	71	;	;	PUNCT
amwa-432	85	72	mean	mean	VERB
amwa-432	85	73	age	age	NOUN
amwa-432	85	74	,	,	PUNCT
amwa-432	85	75	44	44	NUM
amwa-432	85	76	y	y	NOUN
amwa-432	85	77	;	;	PUNCT
amwa-432	85	78	average	average	ADJ
amwa-432	85	79	bmi	bmi	NOUN
amwa-432	85	80	36	36	NUM
amwa-432	85	81	;	;	PUNCT
amwa-432	85	82	82	82	NUM
amwa-432	85	83	%	%	NOUN
amwa-432	85	84	white	white	PROPN
amwa-432	85	85	adults	adult	NOUN
amwa-432	85	86	cor	cor	PROPN
amwa-432	85	87	-	-	PROPN
amwa-432	85	88	ii	ii	ADJ
amwa-432	85	89	85	85	NUM
amwa-432	85	90	%	%	NOUN
amwa-432	85	91	women	woman	NOUN
amwa-432	85	92	;	;	PUNCT
amwa-432	85	93	mean	mean	VERB
amwa-432	85	94	age	age	NOUN
amwa-432	85	95	,	,	PUNCT
amwa-432	85	96	44	44	NUM
amwa-432	85	97	y	y	NOUN
amwa-432	85	98	;	;	PUNCT
amwa-432	85	99	average	average	ADJ
amwa-432	85	100	bmi	bmi	NOUN
amwa-432	85	101	,	,	PUNCT
amwa-432	85	102	36	36	NUM
amwa-432	85	103	;	;	PUNCT
amwa-432	85	104	83	83	NUM
amwa-432	85	105	%	%	NOUN
amwa-432	85	106	white	white	ADJ
amwa-432	85	107	adults	adult	NOUN
amwa-432	85	108	liraglutide	liraglutide	VERB
amwa-432	85	109	saxenda	saxenda	PROPN
amwa-432	85	110	≥12	≥12	ADP
amwa-432	85	111	18	18	NUM
amwa-432	85	112	mg	mg	NOUN
amwa-432	85	113	dial	dial	NOUN
amwa-432	85	114	-	-	PUNCT
amwa-432	85	115	a	a	DET
amwa-432	85	116	-	-	PUNCT
amwa-432	85	117	dose	dose	NOUN
amwa-432	85	118	pen	pen	NOUN
amwa-432	85	119	delivering	deliver	VERB
amwa-432	85	120	customizable	customizable	ADJ
amwa-432	85	121	doses	dose	NOUN
amwa-432	85	122	:	:	PUNCT
amwa-432	85	123	30	30	NUM
amwa-432	85	124	at	at	ADP
amwa-432	85	125	0.6	0.6	NUM
amwa-432	85	126	mg	mg	NUM
amwa-432	85	127	;	;	PUNCT
amwa-432	85	128	15	15	NUM
amwa-432	85	129	at	at	ADP
amwa-432	85	130	1.2	1.2	NUM
amwa-432	85	131	mg	mg	NOUN
amwa-432	85	132	;	;	PUNCT
amwa-432	85	133	10	10	NUM
amwa-432	85	134	at	at	ADP
amwa-432	85	135	1.8	1.8	NUM
amwa-432	85	136	mg	mg	NOUN
amwa-432	85	137	;	;	PUNCT
amwa-432	85	138	7	7	NUM
amwa-432	85	139	at	at	ADP
amwa-432	85	140	2.4	2.4	NUM
amwa-432	85	141	mg	mg	NUM
amwa-432	85	142	;	;	PUNCT
amwa-432	85	143	6	6	NUM
amwa-432	85	144	at	at	ADP
amwa-432	85	145	3	3	NUM
amwa-432	85	146	mg	mg	PROPN
amwa-432	85	147	scale	scale	NOUN
amwa-432	85	148	78	78	NUM
amwa-432	85	149	%	%	NOUN
amwa-432	85	150	women	woman	NOUN
amwa-432	85	151	;	;	PUNCT
amwa-432	85	152	mean	mean	VERB
amwa-432	85	153	age	age	NOUN
amwa-432	85	154	,	,	PUNCT
amwa-432	85	155	45	45	NUM
amwa-432	85	156	y	y	NOUN
amwa-432	85	157	;	;	PUNCT
amwa-432	85	158	average	average	ADJ
amwa-432	85	159	bmi	bmi	NOUN
amwa-432	85	160	,	,	PUNCT
amwa-432	85	161	38	38	NUM
amwa-432	85	162	;	;	PUNCT
amwa-432	85	163	85	85	NUM
amwa-432	85	164	%	%	NOUN
amwa-432	85	165	white	white	ADJ
amwa-432	85	166	adults	adult	NOUN
amwa-432	85	167	semaglutide	semaglutide	ADJ
amwa-432	85	168	wegovy	wegovy	NOUN
amwa-432	85	169	≥12	≥12	NOUN
amwa-432	85	170	single	single	ADJ
amwa-432	85	171	-	-	PUNCT
amwa-432	85	172	use	use	NOUN
amwa-432	85	173	,	,	PUNCT
amwa-432	85	174	color	color	NOUN
amwa-432	85	175	-	-	PUNCT
amwa-432	85	176	coded	code	VERB
amwa-432	85	177	pens	pen	NOUN
amwa-432	85	178	:	:	PUNCT
amwa-432	85	179	teal	teal	NOUN
amwa-432	85	180	,	,	PUNCT
amwa-432	85	181	0.25	0.25	NUM
amwa-432	85	182	mg	mg	NOUN
amwa-432	85	183	;	;	PUNCT
amwa-432	85	184	pink	pink	ADJ
amwa-432	85	185	,	,	PUNCT
amwa-432	85	186	0.5	0.5	NUM
amwa-432	85	187	mg	mg	NUM
amwa-432	85	188	;	;	PUNCT
amwa-432	85	189	brown	brown	ADJ
amwa-432	85	190	,	,	PUNCT
amwa-432	85	191	1	1	NUM
amwa-432	85	192	mg	mg	NUM
amwa-432	85	193	;	;	PUNCT
amwa-432	85	194	blue	blue	ADJ
amwa-432	85	195	,	,	PUNCT
amwa-432	85	196	1.7	1.7	NUM
amwa-432	85	197	mg	mg	NOUN
amwa-432	85	198	;	;	PUNCT
amwa-432	85	199	black	black	ADJ
amwa-432	85	200	,	,	PUNCT
amwa-432	85	201	2.4	2.4	NUM
amwa-432	85	202	mg	mg	NOUN
amwa-432	85	203	step	step	NOUN
amwa-432	85	204	1	1	NUM
amwa-432	85	205	73	73	NUM
amwa-432	85	206	%	%	NOUN
amwa-432	85	207	women	woman	NOUN
amwa-432	85	208	;	;	PUNCT
amwa-432	85	209	mean	mean	VERB
amwa-432	85	210	age	age	NOUN
amwa-432	85	211	,	,	PUNCT
amwa-432	85	212	46	46	NUM
amwa-432	85	213	y	y	NOUN
amwa-432	85	214	;	;	PUNCT
amwa-432	85	215	average	average	ADJ
amwa-432	85	216	bmi	bmi	NOUN
amwa-432	85	217	,	,	PUNCT
amwa-432	85	218	38	38	NUM
amwa-432	85	219	;	;	PUNCT
amwa-432	85	220	75	75	NUM
amwa-432	85	221	%	%	NOUN
amwa-432	85	222	white	white	ADJ
amwa-432	85	223	adults	adult	NOUN
amwa-432	85	224	tirzepatide	tirzepatide	ADV
amwa-432	85	225	zepbound	zepbound	VERB
amwa-432	85	226	≥18	≥18	DET
amwa-432	85	227	single	single	ADJ
amwa-432	85	228	-	-	PUNCT
amwa-432	85	229	use	use	NOUN
amwa-432	85	230	0.5	0.5	NUM
amwa-432	85	231	ml	ml	NOUN
amwa-432	85	232	pen	pen	NOUN
amwa-432	85	233	or	or	CCONJ
amwa-432	85	234	vial	vial	ADJ
amwa-432	85	235	,	,	PUNCT
amwa-432	85	236	comes	come	VERB
amwa-432	85	237	in	in	ADP
amwa-432	85	238	doses	dose	NOUN
amwa-432	85	239	:	:	PUNCT
amwa-432	85	240	2.5	2.5	NUM
amwa-432	85	241	mg	mg	NOUN
amwa-432	85	242	;	;	PUNCT
amwa-432	85	243	5	5	NUM
amwa-432	85	244	mg	mg	NUM
amwa-432	85	245	;	;	PUNCT
amwa-432	85	246	7.5	7.5	NUM
amwa-432	85	247	mg	mg	NUM
amwa-432	85	248	;	;	PUNCT
amwa-432	85	249	10	10	NUM
amwa-432	85	250	mg	mg	NUM
amwa-432	85	251	;	;	PUNCT
amwa-432	85	252	12.5	12.5	NUM
amwa-432	85	253	mg	mg	NOUN
amwa-432	85	254	;	;	PUNCT
amwa-432	85	255	15	15	NUM
amwa-432	85	256	mg	mg	PROPN
amwa-432	85	257	surmount-1	surmount-1	NUM
amwa-432	85	258	67.5	67.5	NUM
amwa-432	85	259	%	%	NOUN
amwa-432	85	260	women	woman	NOUN
amwa-432	85	261	;	;	PUNCT
amwa-432	86	1	mean	mean	VERB
amwa-432	86	2	age	age	NOUN
amwa-432	86	3	,	,	PUNCT
amwa-432	86	4	45	45	NUM
amwa-432	86	5	y	y	NOUN
amwa-432	86	6	;	;	PUNCT
amwa-432	86	7	average	average	ADJ
amwa-432	86	8	bmi	bmi	NOUN
amwa-432	86	9	,	,	PUNCT
amwa-432	86	10	38	38	NUM
amwa-432	86	11	;	;	PUNCT
amwa-432	86	12	70	70	NUM
amwa-432	86	13	%	%	NOUN
amwa-432	86	14	white	white	ADJ
amwa-432	86	15	adults	adult	NOUN
amwa-432	86	16	bmi	bmi	VERB
amwa-432	86	17	,	,	PUNCT
amwa-432	86	18	body	body	NOUN
amwa-432	86	19	mass	mass	PROPN
amwa-432	86	20	index	index	NOUN
amwa-432	86	21	;	;	PUNCT
amwa-432	86	22	cor	cor	PROPN
amwa-432	86	23	-	-	PROPN
amwa-432	86	24	i	i	PROPN
amwa-432	86	25	,	,	PUNCT
amwa-432	86	26	contrave	contrave	VERB
amwa-432	86	27	obesity	obesity	NOUN
amwa-432	86	28	research	research	NOUN
amwa-432	86	29	i	i	PRON
amwa-432	86	30	;	;	PUNCT
amwa-432	86	31	cor	cor	PROPN
amwa-432	86	32	-	-	PROPN
amwa-432	86	33	ii	ii	PROPN
amwa-432	86	34	,	,	PUNCT
amwa-432	86	35	contrave	contrave	VERB
amwa-432	86	36	obesity	obesity	NOUN
amwa-432	86	37	research	research	NOUN
amwa-432	86	38	ii	ii	PROPN
amwa-432	86	39	;	;	PUNCT
amwa-432	86	40	eu	eu	PROPN
amwa-432	86	41	,	,	PUNCT
amwa-432	86	42	european	european	PROPN
amwa-432	86	43	union	union	PROPN
amwa-432	86	44	;	;	PUNCT
amwa-432	86	45	fda	fda	PROPN
amwa-432	86	46	,	,	PUNCT
amwa-432	86	47	us	us	PROPN
amwa-432	86	48	food	food	NOUN
amwa-432	86	49	and	and	CCONJ
amwa-432	86	50	drug	drug	NOUN
amwa-432	86	51	administration	administration	NOUN
amwa-432	86	52	;	;	PUNCT
amwa-432	86	53	otc	otc	PROPN
amwa-432	86	54	,	,	PUNCT
amwa-432	86	55	over	over	ADP
amwa-432	86	56	the	the	DET
amwa-432	86	57	counter	counter	NOUN
amwa-432	86	58	;	;	PUNCT
amwa-432	86	59	scale	scale	NOUN
amwa-432	86	60	,	,	PUNCT
amwa-432	86	61	satiety	satiety	NOUN
amwa-432	86	62	and	and	CCONJ
amwa-432	86	63	clinical	clinical	ADJ
amwa-432	86	64	adiposity	adiposity	NOUN
amwa-432	86	65	liraglutide	liraglutide	NOUN
amwa-432	86	66	evidence	evidence	NOUN
amwa-432	86	67	;	;	PUNCT
amwa-432	86	68	step	step	NOUN
amwa-432	86	69	1	1	NUM
amwa-432	86	70	,	,	PUNCT
amwa-432	86	71	semaglutide	semaglutide	ADJ
amwa-432	86	72	treatment	treatment	NOUN
amwa-432	86	73	effect	effect	NOUN
amwa-432	86	74	in	in	ADP
amwa-432	86	75	people	people	NOUN
amwa-432	86	76	with	with	ADP
amwa-432	86	77	obesity	obesity	NOUN
amwa-432	86	78	;	;	PUNCT
amwa-432	86	79	xendos	xendo	NOUN
amwa-432	86	80	,	,	PUNCT
amwa-432	86	81	xenical	xenical	ADJ
amwa-432	86	82	in	in	ADP
amwa-432	86	83	the	the	DET
amwa-432	86	84	prevention	prevention	NOUN
amwa-432	86	85	of	of	ADP
amwa-432	86	86	diabetes	diabetes	NOUN
amwa-432	86	87	in	in	ADP
amwa-432	86	88	obese	obese	ADJ
amwa-432	86	89	subjects	subject	NOUN
amwa-432	86	90	.	.	PUNCT
amwa-432	86	91	http://www.amwajournal.org	http://www.amwajournal.org	X
amwa-432	87	1	amwajournal.org	amwajournal.org	X
amwa-432	87	2	39incretin	39incretin	NUM
amwa-432	87	3	drug	drug	NOUN
amwa-432	87	4	revolution	revolution	NOUN
amwa-432	87	5	:	:	PUNCT
amwa-432	87	6	the	the	DET
amwa-432	87	7	challenges	challenge	NOUN
amwa-432	87	8	of	of	ADP
amwa-432	87	9	hope	hope	NOUN
amwa-432	87	10	the	the	DET
amwa-432	87	11	incretin	incretin	ADJ
amwa-432	87	12	drug	drug	NOUN
amwa-432	87	13	revolution	revolution	PROPN
amwa-432	87	14	incretin	incretin	NOUN
amwa-432	87	15	drugs	drug	NOUN
amwa-432	87	16	are	be	AUX
amwa-432	87	17	not	not	PART
amwa-432	87	18	new	new	ADJ
amwa-432	87	19	.	.	PUNCT
amwa-432	88	1	liraglutide	liraglutide	PROPN
amwa-432	88	2	debuted	debut	VERB
amwa-432	88	3	a	a	DET
amwa-432	88	4	decade	decade	NOUN
amwa-432	88	5	ago	ago	ADV
amwa-432	88	6	,	,	PUNCT
amwa-432	88	7	but	but	CCONJ
amwa-432	88	8	the	the	DET
amwa-432	88	9	drug	drug	NOUN
amwa-432	88	10	was	be	AUX
amwa-432	88	11	not	not	PART
amwa-432	88	12	as	as	ADV
amwa-432	88	13	effective	effective	ADJ
amwa-432	88	14	compared	compare	VERB
amwa-432	88	15	with	with	ADP
amwa-432	88	16	the	the	DET
amwa-432	88	17	more	more	ADV
amwa-432	88	18	recent	recent	ADJ
amwa-432	88	19	incretin	incretin	ADJ
amwa-432	88	20	drugs	drug	NOUN
amwa-432	88	21	.	.	PUNCT
amwa-432	89	1	the	the	DET
amwa-432	89	2	dose	dose	NOUN
amwa-432	89	3	required	require	VERB
amwa-432	89	4	to	to	PART
amwa-432	89	5	treat	treat	VERB
amwa-432	89	6	obesity	obesity	NOUN
amwa-432	89	7	is	be	AUX
amwa-432	89	8	almost	almost	ADV
amwa-432	89	9	twice	twice	DET
amwa-432	89	10	that	that	DET
amwa-432	89	11	for	for	ADP
amwa-432	89	12	glucose	glucose	NOUN
amwa-432	89	13	management	management	NOUN
amwa-432	89	14	in	in	ADP
amwa-432	89	15	type	type	NOUN
amwa-432	89	16	2	2	NUM
amwa-432	89	17	diabetes	diabetes	NOUN
amwa-432	89	18	.	.	PUNCT
amwa-432	90	1	during	during	ADP
amwa-432	90	2	the	the	DET
amwa-432	90	3	satiety	satiety	NOUN
amwa-432	90	4	and	and	CCONJ
amwa-432	90	5	clinical	clinical	ADJ
amwa-432	90	6	adiposity	adiposity	NOUN
amwa-432	90	7	liraglutide	liraglutide	NOUN
amwa-432	90	8	evidence	evidence	NOUN
amwa-432	90	9	trials	trial	NOUN
amwa-432	90	10	,	,	PUNCT
amwa-432	90	11	liraglutide	liraglutide	VERB
amwa-432	90	12	reduced	reduce	VERB
amwa-432	90	13	total	total	ADJ
amwa-432	90	14	body	body	NOUN
amwa-432	90	15	weight	weight	NOUN
amwa-432	90	16	by	by	ADP
amwa-432	90	17	6.1%.21	6.1%.21	NUM
amwa-432	90	18	liraglutide	liraglutide	NOUN
amwa-432	90	19	did	do	AUX
amwa-432	90	20	not	not	PART
amwa-432	90	21	receive	receive	VERB
amwa-432	90	22	much	much	ADJ
amwa-432	90	23	publicity	publicity	NOUN
amwa-432	90	24	with	with	ADP
amwa-432	90	25	high	high	ADJ
amwa-432	90	26	discontinuation	discontinuation	NOUN
amwa-432	90	27	rates	rate	NOUN
amwa-432	90	28	,	,	PUNCT
amwa-432	90	29	gi	gi	VERB
amwa-432	90	30	side	side	NOUN
amwa-432	90	31	effects	effect	NOUN
amwa-432	90	32	,	,	PUNCT
amwa-432	90	33	and	and	CCONJ
amwa-432	90	34	cancer	cancer	NOUN
amwa-432	90	35	risk	risk	NOUN
amwa-432	90	36	.	.	PUNCT
amwa-432	91	1	to	to	PART
amwa-432	91	2	improve	improve	VERB
amwa-432	91	3	safety	safety	NOUN
amwa-432	91	4	and	and	CCONJ
amwa-432	91	5	effectiveness	effectiveness	NOUN
amwa-432	91	6	,	,	PUNCT
amwa-432	91	7	the	the	DET
amwa-432	91	8	manufacturer	manufacturer	NOUN
amwa-432	91	9	of	of	ADP
amwa-432	91	10	liraglutide	liraglutide	NOUN
amwa-432	91	11	set	set	VERB
amwa-432	91	12	out	out	ADP
amwa-432	91	13	to	to	PART
amwa-432	91	14	find	find	VERB
amwa-432	91	15	a	a	DET
amwa-432	91	16	compound	compound	NOUN
amwa-432	91	17	with	with	ADP
amwa-432	91	18	a	a	DET
amwa-432	91	19	longer	long	ADJ
amwa-432	91	20	half	half	ADJ
amwa-432	91	21	-	-	PUNCT
amwa-432	91	22	life	life	NOUN
amwa-432	91	23	.	.	PUNCT
amwa-432	92	1	researchers	researcher	NOUN
amwa-432	92	2	discovered	discover	VERB
amwa-432	92	3	semaglutide	semaglutide	ADV
amwa-432	92	4	,	,	PUNCT
amwa-432	92	5	extending	extend	VERB
amwa-432	92	6	the	the	DET
amwa-432	92	7	half	half	ADJ
amwa-432	92	8	-	-	PUNCT
amwa-432	92	9	life	life	NOUN
amwa-432	92	10	to	to	ADP
amwa-432	92	11	168	168	NUM
amwa-432	92	12	hours	hour	NOUN
amwa-432	92	13	.	.	PUNCT
amwa-432	93	1	during	during	ADP
amwa-432	93	2	the	the	DET
amwa-432	93	3	semaglutide	semaglutide	ADJ
amwa-432	93	4	treatment	treatment	NOUN
amwa-432	93	5	effect	effect	NOUN
amwa-432	93	6	in	in	ADP
amwa-432	93	7	people	people	NOUN
amwa-432	93	8	with	with	ADP
amwa-432	93	9	obesity	obesity	NOUN
amwa-432	93	10	trials	trial	NOUN
amwa-432	93	11	,	,	PUNCT
amwa-432	93	12	this	this	DET
amwa-432	93	13	compound	compound	NOUN
amwa-432	93	14	improved	improve	VERB
amwa-432	93	15	cardiometabolic	cardiometabolic	ADJ
amwa-432	93	16	health	health	NOUN
amwa-432	93	17	and	and	CCONJ
amwa-432	93	18	reduced	reduce	VERB
amwa-432	93	19	weight	weight	NOUN
amwa-432	93	20	by	by	ADP
amwa-432	93	21	12.6	12.6	NUM
amwa-432	93	22	%	%	NOUN
amwa-432	93	23	(	(	PUNCT
amwa-432	93	24	figure	figure	NOUN
amwa-432	93	25	5).21	5).21	NUM
amwa-432	93	26	but	but	CCONJ
amwa-432	93	27	similar	similar	ADJ
amwa-432	93	28	to	to	PART
amwa-432	93	29	figure	figure	VERB
amwa-432	93	30	4	4	NUM
amwa-432	93	31	.	.	PUNCT
amwa-432	93	32	pharmaceutical	pharmaceutical	ADJ
amwa-432	93	33	action	action	NOUN
amwa-432	93	34	to	to	PART
amwa-432	93	35	extend	extend	VERB
amwa-432	93	36	satiety	satiety	NOUN
amwa-432	93	37	for	for	ADP
amwa-432	93	38	energy	energy	NOUN
amwa-432	93	39	homeostasis.20	homeostasis.20	PROPN
amwa-432	93	40	α	α	PROPN
amwa-432	93	41	-	-	PUNCT
amwa-432	93	42	msh	msh	PROPN
amwa-432	93	43	,	,	PUNCT
amwa-432	93	44	α	α	PROPN
amwa-432	93	45	-	-	PUNCT
amwa-432	93	46	melanocortin	melanocortin	ADJ
amwa-432	93	47	stimulating	stimulating	ADJ
amwa-432	93	48	hormone	hormone	NOUN
amwa-432	93	49	;	;	PUNCT
amwa-432	93	50	agrp	agrp	PROPN
amwa-432	93	51	/	/	SYM
amwa-432	93	52	npy	npy	PROPN
amwa-432	93	53	,	,	PUNCT
amwa-432	93	54	agouti	agouti	NOUN
amwa-432	93	55	-	-	PUNCT
amwa-432	93	56	related	relate	VERB
amwa-432	93	57	peptide	peptide	NOUN
amwa-432	93	58	/	/	SYM
amwa-432	93	59	neuropeptide	neuropeptide	NOUN
amwa-432	93	60	y	y	NOUN
amwa-432	93	61	;	;	PUNCT
amwa-432	93	62	arc	arc	NOUN
amwa-432	93	63	,	,	PUNCT
amwa-432	93	64	arcuate	arcuate	ADJ
amwa-432	93	65	nucleus	nucleus	NOUN
amwa-432	93	66	;	;	PUNCT
amwa-432	93	67	bat	bat	NOUN
amwa-432	93	68	,	,	PUNCT
amwa-432	93	69	brown	brown	ADJ
amwa-432	93	70	adipose	adipose	NOUN
amwa-432	93	71	tissue	tissue	NOUN
amwa-432	93	72	;	;	PUNCT
amwa-432	93	73	cck	cck	ADJ
amwa-432	93	74	,	,	PUNCT
amwa-432	93	75	cholecystokinin	cholecystokinin	NOUN
amwa-432	93	76	;	;	PUNCT
amwa-432	93	77	ee	ee	PROPN
amwa-432	93	78	,	,	PUNCT
amwa-432	93	79	energy	energy	NOUN
amwa-432	93	80	expenditure	expenditure	NOUN
amwa-432	93	81	;	;	PUNCT
amwa-432	93	82	ffas	ffas	NOUN
amwa-432	93	83	,	,	PUNCT
amwa-432	93	84	free	free	ADJ
amwa-432	93	85	fatty	fatty	NOUN
amwa-432	93	86	acids	acid	NOUN
amwa-432	93	87	;	;	PUNCT
amwa-432	93	88	gaba	gaba	PROPN
amwa-432	93	89	,	,	PUNCT
amwa-432	93	90	γ	γ	NOUN
amwa-432	93	91	-	-	ADJ
amwa-432	93	92	aminobutyric	aminobutyric	ADJ
amwa-432	93	93	acid	acid	NOUN
amwa-432	93	94	;	;	PUNCT
amwa-432	94	1	glp-1	glp-1	NOUN
amwa-432	94	2	ra	ra	NOUN
amwa-432	94	3	,	,	PUNCT
amwa-432	94	4	glucagon	glucagon	NOUN
amwa-432	94	5	-	-	PUNCT
amwa-432	94	6	like	like	ADJ
amwa-432	94	7	peptide-1	peptide-1	NOUN
amwa-432	94	8	receptor	receptor	NOUN
amwa-432	94	9	agonist	agonist	NOUN
amwa-432	94	10	drugs	drug	NOUN
amwa-432	94	11	including	include	VERB
amwa-432	94	12	tirzepatide	tirzepatide	NOUN
amwa-432	94	13	;	;	PUNCT
amwa-432	94	14	mc4r	mc4r	PROPN
amwa-432	94	15	,	,	PUNCT
amwa-432	94	16	melanocortin	melanocortin	NOUN
amwa-432	94	17	4	4	NUM
amwa-432	94	18	receptor	receptor	NOUN
amwa-432	94	19	;	;	PUNCT
amwa-432	94	20	pomc	pomc	NOUN
amwa-432	94	21	/	/	SYM
amwa-432	94	22	cart	cart	NOUN
amwa-432	94	23	,	,	PUNCT
amwa-432	94	24	pro	pro	ADJ
amwa-432	94	25	-	-	ADJ
amwa-432	94	26	opiomelanocortin	opiomelanocortin	ADJ
amwa-432	94	27	/	/	SYM
amwa-432	94	28	cocaine	cocaine	NOUN
amwa-432	94	29	-	-	PUNCT
amwa-432	94	30	amphetamine	amphetamine	NOUN
amwa-432	94	31	-	-	PUNCT
amwa-432	94	32	related	relate	VERB
amwa-432	94	33	transcript	transcript	NOUN
amwa-432	94	34	;	;	PUNCT
amwa-432	94	35	pyy	pyy	NOUN
amwa-432	94	36	,	,	PUNCT
amwa-432	94	37	peptide	peptide	NOUN
amwa-432	94	38	yy	yy	PROPN
amwa-432	94	39	;	;	PUNCT
amwa-432	94	40	sns	sns	PROPN
amwa-432	94	41	,	,	PUNCT
amwa-432	94	42	sympathetic	sympathetic	ADJ
amwa-432	94	43	nervous	nervous	ADJ
amwa-432	94	44	system	system	NOUN
amwa-432	94	45	;	;	PUNCT
amwa-432	94	46	wat	wat	ADJ
amwa-432	94	47	,	,	PUNCT
amwa-432	94	48	white	white	ADJ
amwa-432	94	49	adipose	adipose	ADP
amwa-432	94	50	tissue	tissue	NOUN
amwa-432	94	51	;	;	PUNCT
amwa-432	94	52	y1r	y1r	PROPN
amwa-432	94	53	,	,	PUNCT
amwa-432	94	54	npy	npy	NOUN
amwa-432	94	55	1	1	NUM
amwa-432	94	56	receptor	receptor	NOUN
amwa-432	94	57	.	.	PUNCT
amwa-432	95	1	20	20	NUM
amwa-432	95	2	%	%	NOUN
amwa-432	95	3	41	41	NUM
amwa-432	95	4	%	%	NOUN
amwa-432	95	5	32	32	NUM
amwa-432	95	6	%	%	NOUN
amwa-432	95	7	23	23	NUM
amwa-432	95	8	%	%	NOUN
amwa-432	95	9	57	57	NUM
amwa-432	95	10	%	%	NOUN
amwa-432	95	11	65	65	NUM
amwa-432	95	12	%	%	NOUN
amwa-432	95	13	80	80	NUM
amwa-432	95	14	%	%	NOUN
amwa-432	95	15	59	59	NUM
amwa-432	95	16	%	%	NOUN
amwa-432	95	17	68	68	NUM
amwa-432	95	18	%	%	NOUN
amwa-432	95	19	77	77	NUM
amwa-432	95	20	%	%	NOUN
amwa-432	95	21	43	43	NUM
amwa-432	95	22	%	%	NOUN
amwa-432	95	23	35	35	NUM
amwa-432	95	24	%	%	NOUN
amwa-432	95	25	≥≥10	≥≥10	NUM
amwa-432	95	26	%	%	NOUN
amwa-432	95	27	≥≥10	≥≥10	NUM
amwa-432	95	28	%	%	NOUN
amwa-432	95	29	≥≥10	≥≥10	NUM
amwa-432	95	30	%	%	NOUN
amwa-432	95	31	≥≥10	≥≥10	NUM
amwa-432	95	32	%	%	NOUN
amwa-432	95	33	≥≥10	≥≥10	NUM
amwa-432	95	34	%	%	NOUN
amwa-432	95	35	≥≥10	≥≥10	NUM
amwa-432	95	36	%	%	NOUN
amwa-432	95	37	orlistat	orlistat	NOUN
amwa-432	95	38	phen	phen	PROPN
amwa-432	95	39	/	/	SYM
amwa-432	95	40	top	top	ADJ
amwa-432	95	41	nal	nal	ADJ
amwa-432	95	42	/	/	SYM
amwa-432	95	43	bu	bu	NOUN
amwa-432	95	44	liraglutide	liraglutide	NOUN
amwa-432	95	45	semaglutide	semaglutide	ADV
amwa-432	95	46	tirzepatide	tirzepatide	ADP
amwa-432	95	47	%	%	NOUN
amwa-432	95	48	effective	effective	ADJ
amwa-432	95	49	%	%	NOUN
amwa-432	95	50	ineffective	ineffective	ADJ
amwa-432	95	51	figure	figure	NOUN
amwa-432	95	52	5	5	NUM
amwa-432	95	53	.	.	PUNCT
amwa-432	95	54	percent	percent	NOUN
amwa-432	95	55	of	of	ADP
amwa-432	95	56	individuals	individual	NOUN
amwa-432	95	57	experiencing	experience	VERB
amwa-432	95	58	≥10	≥10	ADP
amwa-432	95	59	%	%	NOUN
amwa-432	95	60	weight	weight	NOUN
amwa-432	95	61	reduction	reduction	NOUN
amwa-432	95	62	from	from	ADP
amwa-432	95	63	drug	drug	NOUN
amwa-432	95	64	treatment	treatment	NOUN
amwa-432	95	65	during	during	ADP
amwa-432	95	66	clinical	clinical	ADJ
amwa-432	95	67	trial	trial	NOUN
amwa-432	95	68	testing.17,21	testing.17,21	NOUN
amwa-432	95	69	nal	nal	PROPN
amwa-432	95	70	/	/	SYM
amwa-432	95	71	bu	bu	PROPN
amwa-432	95	72	,	,	PUNCT
amwa-432	95	73	naltrexone	naltrexone	PROPN
amwa-432	95	74	with	with	ADP
amwa-432	95	75	bupropion	bupropion	NOUN
amwa-432	95	76	.	.	PUNCT
amwa-432	96	1	other	other	ADJ
amwa-432	96	2	incretin	incretin	ADJ
amwa-432	96	3	therapies	therapy	NOUN
amwa-432	96	4	,	,	PUNCT
amwa-432	96	5	almost	almost	ADV
amwa-432	96	6	40	40	NUM
amwa-432	96	7	%	%	NOUN
amwa-432	96	8	of	of	ADP
amwa-432	96	9	trial	trial	NOUN
amwa-432	96	10	participants	participant	NOUN
amwa-432	96	11	reported	report	VERB
amwa-432	96	12	nausea	nausea	NOUN
amwa-432	96	13	,	,	PUNCT
amwa-432	96	14	70	70	NUM
amwa-432	96	15	%	%	NOUN
amwa-432	96	16	experienced	experience	VERB
amwa-432	96	17	gi	gi	NOUN
amwa-432	96	18	disorders	disorder	NOUN
amwa-432	96	19	,	,	PUNCT
amwa-432	96	20	and	and	CCONJ
amwa-432	96	21	almost	almost	ADV
amwa-432	96	22	10	10	NUM
amwa-432	96	23	%	%	NOUN
amwa-432	96	24	discontinued	discontinue	VERB
amwa-432	96	25	the	the	DET
amwa-432	96	26	drug.15	drug.15	NOUN
amwa-432	96	27	the	the	DET
amwa-432	96	28	newest	new	ADJ
amwa-432	96	29	incretin	incretin	NOUN
amwa-432	96	30	drug	drug	NOUN
amwa-432	96	31	,	,	PUNCT
amwa-432	96	32	tirzepatide	tirzepatide	ADV
amwa-432	96	33	,	,	PUNCT
amwa-432	96	34	binds	bind	VERB
amwa-432	96	35	glp-1	glp-1	ADP
amwa-432	96	36	and	and	CCONJ
amwa-432	96	37	gip	gip	NOUN
amwa-432	96	38	receptors	receptor	NOUN
amwa-432	96	39	in	in	ADP
amwa-432	96	40	the	the	DET
amwa-432	96	41	gut.16	gut.16	NOUN
amwa-432	96	42	this	this	DET
amwa-432	96	43	dual	dual	ADJ
amwa-432	96	44	-	-	PUNCT
amwa-432	96	45	acting	act	VERB
amwa-432	96	46	drug	drug	NOUN
amwa-432	96	47	has	have	AUX
amwa-432	96	48	been	be	AUX
amwa-432	96	49	the	the	DET
amwa-432	96	50	most	most	ADJ
amwa-432	96	51	http://www.amwajournal.org	http://www.amwajournal.org	PRON
amwa-432	96	52	amwajournal.org	amwajournal.org	X
amwa-432	96	53	40incretin	40incretin	NUM
amwa-432	96	54	drug	drug	NOUN
amwa-432	96	55	revolution	revolution	PROPN
amwa-432	96	56	:	:	PUNCT
amwa-432	96	57	the	the	DET
amwa-432	96	58	challenges	challenge	NOUN
amwa-432	96	59	of	of	ADP
amwa-432	96	60	hope	hope	NOUN
amwa-432	96	61	successful	successful	ADJ
amwa-432	96	62	incretin	incretin	NOUN
amwa-432	96	63	therapy	therapy	NOUN
amwa-432	96	64	thus	thus	ADV
amwa-432	96	65	far	far	ADV
amwa-432	96	66	,	,	PUNCT
amwa-432	96	67	with	with	ADP
amwa-432	96	68	62	62	NUM
amwa-432	96	69	%	%	NOUN
amwa-432	96	70	of	of	ADP
amwa-432	96	71	participants	participant	NOUN
amwa-432	96	72	having	have	VERB
amwa-432	96	73	≥15	≥15	NOUN
amwa-432	96	74	%	%	VERB
amwa-432	96	75	weight	weight	NOUN
amwa-432	96	76	reduction	reduction	NOUN
amwa-432	96	77	,	,	PUNCT
amwa-432	96	78	and	and	CCONJ
amwa-432	96	79	more	more	ADJ
amwa-432	96	80	than	than	ADP
amwa-432	96	81	half	half	NOUN
amwa-432	96	82	having	have	VERB
amwa-432	96	83	≥20	≥20	NOUN
amwa-432	96	84	%	%	NOUN
amwa-432	96	85	weight	weight	NOUN
amwa-432	96	86	reduction	reduction	NOUN
amwa-432	96	87	(	(	PUNCT
amwa-432	96	88	figure	figure	NOUN
amwa-432	96	89	6	6	NUM
amwa-432	96	90	)	)	PUNCT
amwa-432	96	91	.	.	PUNCT
amwa-432	97	1	however	however	ADV
amwa-432	97	2	,	,	PUNCT
amwa-432	97	3	about	about	ADV
amwa-432	97	4	a	a	DET
amwa-432	97	5	quarter	quarter	NOUN
amwa-432	97	6	of	of	ADP
amwa-432	97	7	participants	participant	NOUN
amwa-432	97	8	discontinue	discontinue	VERB
amwa-432	97	9	treatment	treatment	NOUN
amwa-432	97	10	because	because	SCONJ
amwa-432	97	11	of	of	ADP
amwa-432	97	12	gi	gi	VERB
amwa-432	97	13	symptoms.22	symptoms.22	NOUN
amwa-432	97	14	it	it	PRON
amwa-432	97	15	has	have	AUX
amwa-432	97	16	been	be	AUX
amwa-432	97	17	shown	show	VERB
amwa-432	97	18	that	that	SCONJ
amwa-432	97	19	incretin	incretin	ADJ
amwa-432	97	20	therapies	therapy	NOUN
amwa-432	97	21	remain	remain	VERB
amwa-432	97	22	ineffective	ineffective	ADJ
amwa-432	97	23	for	for	ADP
amwa-432	97	24	about	about	ADV
amwa-432	97	25	20	20	NUM
amwa-432	97	26	%	%	NOUN
amwa-432	97	27	of	of	ADP
amwa-432	97	28	individuals.23	individuals.23	NOUN
amwa-432	97	29	some	some	DET
amwa-432	97	30	patients	patient	NOUN
amwa-432	97	31	require	require	VERB
amwa-432	97	32	dose	dose	NOUN
amwa-432	97	33	adjustments	adjustment	NOUN
amwa-432	97	34	,	,	PUNCT
amwa-432	97	35	therapy	therapy	NOUN
amwa-432	97	36	changes	change	NOUN
amwa-432	97	37	,	,	PUNCT
amwa-432	97	38	or	or	CCONJ
amwa-432	97	39	surgery	surgery	NOUN
amwa-432	97	40	to	to	PART
amwa-432	97	41	reach	reach	VERB
amwa-432	97	42	weight	weight	NOUN
amwa-432	97	43	goals	goal	NOUN
amwa-432	97	44	.	.	PUNCT
amwa-432	98	1	although	although	SCONJ
amwa-432	98	2	there	there	PRON
amwa-432	98	3	are	be	VERB
amwa-432	98	4	several	several	ADJ
amwa-432	98	5	known	know	VERB
amwa-432	98	6	benefits	benefit	NOUN
amwa-432	98	7	for	for	ADP
amwa-432	98	8	incretin	incretin	ADJ
amwa-432	98	9	therapies	therapy	NOUN
amwa-432	98	10	,	,	PUNCT
amwa-432	98	11	several	several	ADJ
amwa-432	98	12	challenges	challenge	NOUN
amwa-432	98	13	remain	remain	VERB
amwa-432	98	14	.	.	PUNCT
amwa-432	99	1	challenges	challenge	NOUN
amwa-432	99	2	of	of	ADP
amwa-432	99	3	incretin	incretin	NOUN
amwa-432	99	4	therapy	therapy	NOUN
amwa-432	99	5	:	:	PUNCT
amwa-432	99	6	shifting	shift	VERB
amwa-432	99	7	satiety	satiety	NOUN
amwa-432	99	8	the	the	DET
amwa-432	99	9	incretin	incretin	ADJ
amwa-432	99	10	drug	drug	NOUN
amwa-432	99	11	revolution	revolution	NOUN
amwa-432	99	12	brings	bring	VERB
amwa-432	99	13	hope	hope	NOUN
amwa-432	99	14	for	for	ADP
amwa-432	99	15	treating	treat	VERB
amwa-432	99	16	obesity	obesity	NOUN
amwa-432	99	17	and	and	CCONJ
amwa-432	99	18	many	many	ADJ
amwa-432	99	19	weight	weight	NOUN
amwa-432	99	20	-	-	PUNCT
amwa-432	99	21	related	relate	VERB
amwa-432	99	22	conditions	condition	NOUN
amwa-432	99	23	.	.	PUNCT
amwa-432	100	1	however	however	ADV
amwa-432	100	2	,	,	PUNCT
amwa-432	100	3	sympathetic	sympathetic	ADJ
amwa-432	100	4	-	-	PUNCT
amwa-432	100	5	extension	extension	NOUN
amwa-432	100	6	of	of	ADP
amwa-432	100	7	satiety	satiety	NOUN
amwa-432	100	8	may	may	AUX
amwa-432	100	9	increase	increase	VERB
amwa-432	100	10	long	long	ADJ
amwa-432	100	11	-	-	PUNCT
amwa-432	100	12	term	term	NOUN
amwa-432	100	13	risks	risk	NOUN
amwa-432	100	14	for	for	ADP
amwa-432	100	15	chronic	chronic	ADJ
amwa-432	100	16	disease	disease	NOUN
amwa-432	100	17	,	,	PUNCT
amwa-432	100	18	including	include	VERB
amwa-432	100	19	risk	risk	NOUN
amwa-432	100	20	for	for	ADP
amwa-432	100	21	renal	renal	ADJ
amwa-432	100	22	disorders	disorder	NOUN
amwa-432	100	23	and	and	CCONJ
amwa-432	100	24	thyroid	thyroid	NOUN
amwa-432	100	25	cancer.16	cancer.16	VERB
amwa-432	100	26	the	the	DET
amwa-432	100	27	brain	brain	NOUN
amwa-432	100	28	’s	’s	PART
amwa-432	100	29	default	default	NOUN
amwa-432	100	30	hunger	hunger	NOUN
amwa-432	100	31	state	state	NOUN
amwa-432	100	32	may	may	AUX
amwa-432	100	33	support	support	VERB
amwa-432	100	34	long	long	ADJ
amwa-432	100	35	-	-	PUNCT
amwa-432	100	36	term	term	NOUN
amwa-432	100	37	health	health	NOUN
amwa-432	100	38	,	,	PUNCT
amwa-432	100	39	fueling	fuel	VERB
amwa-432	100	40	cellular	cellular	ADJ
amwa-432	100	41	activity	activity	NOUN
amwa-432	100	42	through	through	ADP
amwa-432	100	43	fatty	fatty	NOUN
amwa-432	100	44	acid	acid	ADJ
amwa-432	100	45	metabolism	metabolism	NOUN
amwa-432	100	46	.	.	PUNCT
amwa-432	101	1	in	in	ADP
amwa-432	101	2	contrast	contrast	NOUN
amwa-432	101	3	,	,	PUNCT
amwa-432	101	4	incretin	incretin	ADJ
amwa-432	101	5	drugs	drug	NOUN
amwa-432	101	6	shift	shift	VERB
amwa-432	101	7	the	the	DET
amwa-432	101	8	metabolic	metabolic	NOUN
amwa-432	101	9	state	state	NOUN
amwa-432	101	10	to	to	PART
amwa-432	101	11	satiety	satiety	VERB
amwa-432	101	12	,	,	PUNCT
amwa-432	101	13	forcing	force	VERB
amwa-432	101	14	the	the	DET
amwa-432	101	15	brain	brain	NOUN
amwa-432	101	16	and	and	CCONJ
amwa-432	101	17	other	other	ADJ
amwa-432	101	18	tissues	tissue	NOUN
amwa-432	101	19	to	to	PART
amwa-432	101	20	rely	rely	VERB
amwa-432	101	21	on	on	ADP
amwa-432	101	22	glucose.24	glucose.24	PROPN
amwa-432	101	23	although	although	SCONJ
amwa-432	101	24	the	the	DET
amwa-432	101	25	consequences	consequence	NOUN
amwa-432	101	26	of	of	ADP
amwa-432	101	27	this	this	DET
amwa-432	101	28	shift	shift	NOUN
amwa-432	101	29	are	be	AUX
amwa-432	101	30	unclear	unclear	ADJ
amwa-432	101	31	,	,	PUNCT
amwa-432	101	32	sympathomimetic	sympathomimetic	ADJ
amwa-432	101	33	and	and	CCONJ
amwa-432	101	34	incretin	incretin	ADJ
amwa-432	101	35	drugs	drug	NOUN
amwa-432	101	36	increase	increase	VERB
amwa-432	101	37	risk	risk	NOUN
amwa-432	101	38	for	for	ADP
amwa-432	101	39	hypertension	hypertension	NOUN
amwa-432	101	40	,	,	PUNCT
amwa-432	101	41	glaucoma	glaucoma	NOUN
amwa-432	101	42	,	,	PUNCT
amwa-432	101	43	and	and	CCONJ
amwa-432	101	44	heart	heart	NOUN
amwa-432	101	45	rate	rate	NOUN
amwa-432	101	46	(	(	PUNCT
amwa-432	101	47	table	table	NOUN
amwa-432	101	48	2).25,26	2).25,26	NUM
amwa-432	101	49	incretin	incretin	NOUN
amwa-432	101	50	drugs	drug	NOUN
amwa-432	101	51	may	may	AUX
amwa-432	101	52	also	also	ADV
amwa-432	101	53	come	come	VERB
amwa-432	101	54	with	with	ADP
amwa-432	101	55	increased	increase	VERB
amwa-432	101	56	risk	risk	NOUN
amwa-432	101	57	for	for	ADP
amwa-432	101	58	anxiety	anxiety	NOUN
amwa-432	101	59	.	.	PUNCT
amwa-432	102	1	one	one	NUM
amwa-432	102	2	study	study	NOUN
amwa-432	102	3	linked	link	VERB
amwa-432	102	4	chronic	chronic	ADJ
amwa-432	102	5	activation	activation	NOUN
amwa-432	102	6	of	of	ADP
amwa-432	102	7	agrp	agrp	NOUN
amwa-432	102	8	/	/	SYM
amwa-432	102	9	npy	npy	PROPN
amwa-432	102	10	neurons	neuron	NOUN
amwa-432	102	11	with	with	ADP
amwa-432	102	12	increased	increase	VERB
amwa-432	102	13	anxiety	anxiety	NOUN
amwa-432	102	14	and	and	CCONJ
amwa-432	102	15	colitis.27	colitis.27	PROPN
amwa-432	102	16	supporting	support	VERB
amwa-432	102	17	this	this	PRON
amwa-432	102	18	,	,	PUNCT
amwa-432	102	19	some	some	DET
amwa-432	102	20	individuals	individual	NOUN
amwa-432	102	21	taking	take	VERB
amwa-432	102	22	incretin	incretin	ADJ
amwa-432	102	23	drugs	drug	NOUN
amwa-432	102	24	report	report	NOUN
amwa-432	102	25	increased	increase	VERB
amwa-432	102	26	anhedonia	anhedonia	NOUN
amwa-432	102	27	and	and	CCONJ
amwa-432	102	28	suicidality.15	suicidality.15	NOUN
amwa-432	102	29	other	other	ADJ
amwa-432	102	30	challenges	challenge	NOUN
amwa-432	102	31	of	of	ADP
amwa-432	102	32	incretin	incretin	ADJ
amwa-432	102	33	drugs	drug	NOUN
amwa-432	102	34	are	be	AUX
amwa-432	102	35	linked	link	VERB
amwa-432	102	36	to	to	ADP
amwa-432	102	37	gastric	gastric	ADJ
amwa-432	102	38	emptying	empty	VERB
amwa-432	102	39	and	and	CCONJ
amwa-432	102	40	include	include	VERB
amwa-432	102	41	ileus	ileus	NOUN
amwa-432	102	42	,	,	PUNCT
amwa-432	102	43	gastroparesis	gastroparesis	NOUN
amwa-432	102	44	,	,	PUNCT
amwa-432	102	45	and	and	CCONJ
amwa-432	102	46	decreased	decrease	VERB
amwa-432	102	47	drug	drug	NOUN
amwa-432	102	48	absorption.28,29	absorption.28,29	NOUN
amwa-432	102	49	another	another	DET
amwa-432	102	50	complicating	complicate	VERB
amwa-432	102	51	issue	issue	NOUN
amwa-432	102	52	includes	include	VERB
amwa-432	102	53	the	the	DET
amwa-432	102	54	plateau	plateau	NOUN
amwa-432	102	55	effect	effect	NOUN
amwa-432	102	56	.	.	PUNCT
amwa-432	103	1	over	over	ADP
amwa-432	103	2	time	time	NOUN
amwa-432	103	3	,	,	PUNCT
amwa-432	103	4	increased	increase	VERB
amwa-432	103	5	incretin	incretin	ADJ
amwa-432	103	6	drug	drug	NOUN
amwa-432	103	7	dosing	dose	VERB
amwa-432	103	8	may	may	AUX
amwa-432	103	9	no	no	ADV
amwa-432	103	10	longer	long	ADV
amwa-432	103	11	decrease	decrease	VERB
amwa-432	103	12	net	net	ADJ
amwa-432	103	13	body	body	NOUN
amwa-432	103	14	mass	mass	NOUN
amwa-432	103	15	.	.	PUNCT
amwa-432	104	1	this	this	DET
amwa-432	104	2	effect	effect	NOUN
amwa-432	104	3	has	have	AUX
amwa-432	104	4	been	be	AUX
amwa-432	104	5	reported	report	VERB
amwa-432	104	6	by	by	ADP
amwa-432	104	7	individuals	individual	NOUN
amwa-432	104	8	taking	take	VERB
amwa-432	104	9	semaglutide	semaglutide	ADV
amwa-432	104	10	and	and	CCONJ
amwa-432	104	11	highlights	highlight	VERB
amwa-432	104	12	lifestyle	lifestyle	NOUN
amwa-432	104	13	modifications	modification	NOUN
amwa-432	104	14	as	as	ADP
amwa-432	104	15	an	an	DET
amwa-432	104	16	important	important	ADJ
amwa-432	104	17	part	part	NOUN
amwa-432	104	18	of	of	ADP
amwa-432	104	19	overall	overall	ADJ
amwa-432	104	20	treatment.15	treatment.15	NOUN
amwa-432	104	21	using	use	VERB
amwa-432	104	22	incretin	incretin	NOUN
amwa-432	104	23	therapies	therapy	NOUN
amwa-432	104	24	requires	require	VERB
amwa-432	104	25	a	a	DET
amwa-432	104	26	life	life	NOUN
amwa-432	104	27	-	-	PUNCT
amwa-432	104	28	long	long	ADJ
amwa-432	104	29	commitment	commitment	NOUN
amwa-432	104	30	because	because	SCONJ
amwa-432	104	31	health	health	NOUN
amwa-432	104	32	gains	gain	NOUN
amwa-432	104	33	disappear	disappear	VERB
amwa-432	104	34	with	with	ADP
amwa-432	104	35	discontinuation	discontinuation	NOUN
amwa-432	104	36	.	.	PUNCT
amwa-432	105	1	some	some	DET
amwa-432	105	2	studies	study	NOUN
amwa-432	105	3	report	report	VERB
amwa-432	105	4	up	up	ADP
amwa-432	105	5	to	to	PART
amwa-432	105	6	two	two	NUM
amwa-432	105	7	-	-	PUNCT
amwa-432	105	8	thirds	third	NOUN
amwa-432	105	9	of	of	ADP
amwa-432	105	10	the	the	DET
amwa-432	105	11	original	original	ADJ
amwa-432	105	12	weight	weight	NOUN
amwa-432	105	13	returns	return	NOUN
amwa-432	105	14	after	after	ADP
amwa-432	105	15	discontinuation.29	discontinuation.29	NOUN
amwa-432	105	16	looking	look	VERB
amwa-432	105	17	ahead	ahead	ADV
amwa-432	105	18	in	in	ADP
amwa-432	105	19	summary	summary	NOUN
amwa-432	105	20	,	,	PUNCT
amwa-432	105	21	incretin	incretin	ADJ
amwa-432	105	22	therapies	therapy	NOUN
amwa-432	105	23	bring	bring	VERB
amwa-432	105	24	a	a	DET
amwa-432	105	25	dynamic	dynamic	ADJ
amwa-432	105	26	phase	phase	NOUN
amwa-432	105	27	in	in	ADP
amwa-432	105	28	drug	drug	NOUN
amwa-432	105	29	development	development	NOUN
amwa-432	105	30	for	for	ADP
amwa-432	105	31	treating	treat	VERB
amwa-432	105	32	obesity	obesity	NOUN
amwa-432	105	33	.	.	PUNCT
amwa-432	106	1	these	these	DET
amwa-432	106	2	drugs	drug	NOUN
amwa-432	106	3	lower	low	ADJ
amwa-432	106	4	glycemic	glycemic	ADJ
amwa-432	106	5	index	index	NOUN
amwa-432	106	6	,	,	PUNCT
amwa-432	106	7	reduce	reduce	VERB
amwa-432	106	8	cardiovascular	cardiovascular	ADJ
amwa-432	106	9	risk	risk	NOUN
amwa-432	106	10	,	,	PUNCT
amwa-432	106	11	and	and	CCONJ
amwa-432	106	12	may	may	AUX
amwa-432	106	13	benefit	benefit	VERB
amwa-432	106	14	liver	liver	NOUN
amwa-432	106	15	and	and	CCONJ
amwa-432	106	16	neurodegenerative	neurodegenerative	ADJ
amwa-432	106	17	conditions	condition	NOUN
amwa-432	106	18	.	.	PUNCT
amwa-432	107	1	however	however	ADV
amwa-432	107	2	,	,	PUNCT
amwa-432	107	3	the	the	DET
amwa-432	107	4	health	health	NOUN
amwa-432	107	5	risks	risk	NOUN
amwa-432	107	6	of	of	ADP
amwa-432	107	7	prolonged	prolonged	ADJ
amwa-432	107	8	satiety	satiety	NOUN
amwa-432	107	9	states	state	NOUN
amwa-432	107	10	to	to	ADP
amwa-432	107	11	cardiac	cardiac	ADJ
amwa-432	107	12	,	,	PUNCT
amwa-432	107	13	renal	renal	ADJ
amwa-432	107	14	,	,	PUNCT
amwa-432	107	15	and	and	CCONJ
amwa-432	107	16	other	other	ADJ
amwa-432	107	17	tissues	tissue	NOUN
amwa-432	107	18	remain	remain	VERB
amwa-432	107	19	unclear	unclear	ADJ
amwa-432	107	20	.	.	PUNCT
amwa-432	108	1	incretin	incretin	NOUN
amwa-432	108	2	drugs	drug	NOUN
amwa-432	108	3	have	have	AUX
amwa-432	108	4	been	be	AUX
amwa-432	108	5	linked	link	VERB
amwa-432	108	6	to	to	ADP
amwa-432	108	7	increased	increase	VERB
amwa-432	108	8	risk	risk	NOUN
amwa-432	108	9	for	for	ADP
amwa-432	108	10	thyroid	thyroid	NOUN
amwa-432	108	11	cancer	cancer	NOUN
amwa-432	108	12	,	,	PUNCT
amwa-432	108	13	suicidality	suicidality	NOUN
amwa-432	108	14	,	,	PUNCT
amwa-432	108	15	and	and	CCONJ
amwa-432	108	16	elevated	elevated	ADJ
amwa-432	108	17	heart	heart	NOUN
amwa-432	108	18	rate	rate	NOUN
amwa-432	108	19	.	.	PUNCT
amwa-432	109	1	these	these	DET
amwa-432	109	2	medication	medication	NOUN
amwa-432	109	3	side	side	NOUN
amwa-432	109	4	effects	effect	NOUN
amwa-432	109	5	must	must	AUX
amwa-432	109	6	be	be	AUX
amwa-432	109	7	balanced	balance	VERB
amwa-432	109	8	with	with	ADP
amwa-432	109	9	health	health	NOUN
amwa-432	109	10	benefits	benefit	NOUN
amwa-432	109	11	and	and	CCONJ
amwa-432	109	12	cost	cost	NOUN
amwa-432	109	13	,	,	PUNCT
amwa-432	109	14	which	which	PRON
amwa-432	109	15	factor	factor	VERB
amwa-432	109	16	heavily	heavily	ADV
amwa-432	109	17	into	into	ADP
amwa-432	109	18	optimizing	optimize	VERB
amwa-432	109	19	individualized	individualized	ADJ
amwa-432	109	20	clinical	clinical	ADJ
amwa-432	109	21	obesity	obesity	NOUN
amwa-432	109	22	treatment	treatment	NOUN
amwa-432	109	23	plans	plan	NOUN
amwa-432	109	24	.	.	PUNCT
amwa-432	110	1	given	give	VERB
amwa-432	110	2	the	the	DET
amwa-432	110	3	limited	limited	ADJ
amwa-432	110	4	number	number	NOUN
amwa-432	110	5	of	of	ADP
amwa-432	110	6	high	high	ADJ
amwa-432	110	7	-	-	PUNCT
amwa-432	110	8	quality	quality	NOUN
amwa-432	110	9	randomized	randomize	VERB
amwa-432	110	10	trials	trial	NOUN
amwa-432	110	11	comparing	compare	VERB
amwa-432	110	12	obesity	obesity	NOUN
amwa-432	110	13	drugs	drug	NOUN
amwa-432	110	14	,	,	PUNCT
amwa-432	110	15	doctors	doctor	NOUN
amwa-432	110	16	must	must	AUX
amwa-432	110	17	resort	resort	VERB
amwa-432	110	18	to	to	ADP
amwa-432	110	19	trial	trial	NOUN
amwa-432	110	20	-	-	PUNCT
amwa-432	110	21	and	and	CCONJ
amwa-432	110	22	-	-	PUNCT
amwa-432	110	23	error	error	NOUN
amwa-432	110	24	to	to	PART
amwa-432	110	25	predict	predict	VERB
amwa-432	110	26	usefulness	usefulness	NOUN
amwa-432	110	27	.	.	PUNCT
amwa-432	111	1	in	in	ADP
amwa-432	111	2	addition	addition	NOUN
amwa-432	111	3	,	,	PUNCT
amwa-432	111	4	long	long	ADJ
amwa-432	111	5	-	-	PUNCT
amwa-432	111	6	term	term	NOUN
amwa-432	111	7	safety	safety	NOUN
amwa-432	111	8	studies	study	NOUN
amwa-432	111	9	in	in	ADP
amwa-432	111	10	diverse	diverse	ADJ
amwa-432	111	11	populations	population	NOUN
amwa-432	111	12	are	be	AUX
amwa-432	111	13	needed	need	VERB
amwa-432	111	14	to	to	PART
amwa-432	111	15	better	well	ADV
amwa-432	111	16	understand	understand	VERB
amwa-432	111	17	incretin	incretin	ADJ
amwa-432	111	18	drug	drug	NOUN
amwa-432	111	19	effects	effect	NOUN
amwa-432	111	20	on	on	ADP
amwa-432	111	21	growth	growth	NOUN
amwa-432	111	22	and	and	CCONJ
amwa-432	111	23	development	development	NOUN
amwa-432	111	24	.	.	PUNCT
amwa-432	112	1	by	by	ADP
amwa-432	112	2	2030	2030	NUM
amwa-432	112	3	,	,	PUNCT
amwa-432	112	4	more	more	ADJ
amwa-432	112	5	than	than	ADP
amwa-432	112	6	8.5	8.5	NUM
amwa-432	112	7	billion	billion	NUM
amwa-432	112	8	people	people	NOUN
amwa-432	112	9	are	be	AUX
amwa-432	112	10	estimated	estimate	VERB
amwa-432	112	11	to	to	PART
amwa-432	112	12	meet	meet	VERB
amwa-432	112	13	criteria	criterion	NOUN
amwa-432	112	14	for	for	ADP
amwa-432	112	15	obesity	obesity	NOUN
amwa-432	112	16	worldwide.10	worldwide.10	NOUN
amwa-432	112	17	now	now	ADV
amwa-432	112	18	more	more	ADJ
amwa-432	112	19	than	than	ADP
amwa-432	112	20	ever	ever	ADV
amwa-432	112	21	,	,	PUNCT
amwa-432	112	22	learning	learn	VERB
amwa-432	112	23	from	from	ADP
amwa-432	112	24	past	past	ADJ
amwa-432	112	25	mistakes	mistake	NOUN
amwa-432	112	26	can	can	AUX
amwa-432	112	27	help	help	VERB
amwa-432	112	28	improve	improve	VERB
amwa-432	112	29	the	the	DET
amwa-432	112	30	quality	quality	NOUN
amwa-432	112	31	of	of	ADP
amwa-432	112	32	clinical	clinical	ADJ
amwa-432	112	33	obesity	obesity	NOUN
amwa-432	112	34	care	care	NOUN
amwa-432	112	35	.	.	PUNCT
amwa-432	113	1	it	it	PRON
amwa-432	113	2	is	be	AUX
amwa-432	113	3	crucial	crucial	ADJ
amwa-432	113	4	to	to	PART
amwa-432	113	5	determine	determine	VERB
amwa-432	113	6	the	the	DET
amwa-432	113	7	risks	risk	NOUN
amwa-432	113	8	and	and	CCONJ
amwa-432	113	9	long	long	ADJ
amwa-432	113	10	-	-	PUNCT
amwa-432	113	11	term	term	NOUN
amwa-432	113	12	health	health	NOUN
amwa-432	113	13	benefits	benefit	NOUN
amwa-432	113	14	of	of	ADP
amwa-432	113	15	bariatric	bariatric	ADJ
amwa-432	113	16	surgery	surgery	NOUN
amwa-432	113	17	,	,	PUNCT
amwa-432	113	18	drug	drug	NOUN
amwa-432	113	19	therapy	therapy	NOUN
amwa-432	113	20	,	,	PUNCT
amwa-432	113	21	and	and	CCONJ
amwa-432	113	22	combination	combination	NOUN
amwa-432	113	23	treatments	treatment	NOUN
amwa-432	113	24	to	to	PART
amwa-432	113	25	help	help	VERB
amwa-432	113	26	guide	guide	VERB
amwa-432	113	27	future	future	ADJ
amwa-432	113	28	clinical	clinical	ADJ
amwa-432	113	29	practice	practice	NOUN
amwa-432	113	30	.	.	PUNCT
amwa-432	114	1	acknowledgments	acknowledgment	NOUN
amwa-432	114	2	i	i	PRON
amwa-432	114	3	thank	thank	VERB
amwa-432	114	4	naomi	naomi	PROPN
amwa-432	114	5	b.	b.	PROPN
amwa-432	114	6	bishop	bishop	PROPN
amwa-432	114	7	,	,	PUNCT
amwa-432	114	8	md	md	PROPN
amwa-432	114	9	,	,	PUNCT
amwa-432	114	10	for	for	ADP
amwa-432	114	11	her	her	PRON
amwa-432	114	12	review	review	NOUN
amwa-432	114	13	of	of	ADP
amwa-432	114	14	the	the	DET
amwa-432	114	15	manuscript	manuscript	NOUN
amwa-432	114	16	.	.	PUNCT
amwa-432	115	1	all	all	DET
amwa-432	115	2	figures	figure	NOUN
amwa-432	115	3	and	and	CCONJ
amwa-432	115	4	tables	table	NOUN
amwa-432	115	5	are	be	AUX
amwa-432	115	6	compiled	compile	VERB
amwa-432	115	7	,	,	PUNCT
amwa-432	115	8	graphed	graph	VERB
amwa-432	115	9	,	,	PUNCT
amwa-432	115	10	and	and	CCONJ
amwa-432	115	11	designed	design	VERB
amwa-432	115	12	by	by	ADP
amwa-432	115	13	the	the	DET
amwa-432	115	14	author	author	NOUN
amwa-432	115	15	.	.	PUNCT
amwa-432	116	1	the	the	DET
amwa-432	116	2	references	reference	NOUN
amwa-432	116	3	used	use	VERB
amwa-432	116	4	in	in	ADP
amwa-432	116	5	the	the	DET
amwa-432	116	6	tables	table	NOUN
amwa-432	116	7	and	and	CCONJ
amwa-432	116	8	graphs	graph	NOUN
amwa-432	116	9	are	be	AUX
amwa-432	116	10	cited	cite	VERB
amwa-432	116	11	.	.	PUNCT
amwa-432	117	1	author	author	NOUN
amwa-432	117	2	declaration	declaration	NOUN
amwa-432	117	3	and	and	CCONJ
amwa-432	117	4	disclosures	disclosure	NOUN
amwa-432	117	5	:	:	PUNCT
amwa-432	117	6	the	the	DET
amwa-432	117	7	author	author	NOUN
amwa-432	117	8	notes	note	VERB
amwa-432	117	9	no	no	DET
amwa-432	117	10	commercial	commercial	ADJ
amwa-432	117	11	associations	association	NOUN
amwa-432	117	12	that	that	PRON
amwa-432	117	13	may	may	AUX
amwa-432	117	14	pose	pose	VERB
amwa-432	117	15	a	a	DET
amwa-432	117	16	conflict	conflict	NOUN
amwa-432	117	17	of	of	ADP
amwa-432	117	18	interest	interest	NOUN
amwa-432	117	19	in	in	ADP
amwa-432	117	20	relation	relation	NOUN
amwa-432	117	21	to	to	ADP
amwa-432	117	22	this	this	DET
amwa-432	117	23	article	article	NOUN
amwa-432	117	24	.	.	PUNCT
amwa-432	118	1	author	author	NOUN
amwa-432	118	2	contact	contact	PROPN
amwa-432	118	3	:	:	PUNCT
amwa-432	119	1	racelis@msn.com	racelis@msn.com	PROPN
amwa-432	119	2	references	reference	VERB
amwa-432	119	3	1	1	NUM
amwa-432	119	4	.	.	PUNCT
amwa-432	120	1	colman	colman	PROPN
amwa-432	120	2	e.	e.	PROPN
amwa-432	120	3	anorectics	anorectics	PROPN
amwa-432	120	4	on	on	ADP
amwa-432	120	5	trial	trial	NOUN
amwa-432	120	6	:	:	PUNCT
amwa-432	120	7	a	a	DET
amwa-432	120	8	half	half	ADJ
amwa-432	120	9	century	century	NOUN
amwa-432	120	10	of	of	ADP
amwa-432	120	11	federal	federal	ADJ
amwa-432	120	12	regulation	regulation	NOUN
amwa-432	120	13	of	of	ADP
amwa-432	120	14	prescription	prescription	NOUN
amwa-432	120	15	appetite	appetite	NOUN
amwa-432	120	16	suppressants	suppressant	NOUN
amwa-432	120	17	.	.	PUNCT
amwa-432	121	1	ann	ann	PROPN
amwa-432	121	2	intern	intern	PROPN
amwa-432	121	3	med	med	PROPN
amwa-432	121	4	.	.	PUNCT
amwa-432	122	1	2005	2005	NUM
amwa-432	122	2	;	;	PUNCT
amwa-432	122	3	143(5):380	143(5):380	NUM
amwa-432	122	4	-	-	SYM
amwa-432	122	5	385	385	NUM
amwa-432	122	6	.	.	PUNCT
amwa-432	123	1	2	2	NUM
amwa-432	123	2	.	.	X
amwa-432	123	3	wen	wen	PROPN
amwa-432	123	4	x	x	PROPN
amwa-432	123	5	,	,	PUNCT
amwa-432	123	6	zhang	zhang	PROPN
amwa-432	123	7	b	b	PROPN
amwa-432	123	8	,	,	PUNCT
amwa-432	123	9	wu	wu	PROPN
amwa-432	123	10	b	b	PROPN
amwa-432	123	11	,	,	PUNCT
amwa-432	123	12	et	et	PROPN
amwa-432	123	13	al	al	PROPN
amwa-432	123	14	.	.	PUNCT
amwa-432	124	1	signaling	signal	VERB
amwa-432	124	2	pathways	pathway	NOUN
amwa-432	124	3	in	in	ADP
amwa-432	124	4	obesity	obesity	NOUN
amwa-432	124	5	:	:	PUNCT
amwa-432	124	6	mechanisms	mechanism	NOUN
amwa-432	124	7	and	and	CCONJ
amwa-432	124	8	therapeutic	therapeutic	ADJ
amwa-432	124	9	interventions	intervention	NOUN
amwa-432	124	10	.	.	PUNCT
amwa-432	125	1	signal	signal	ADJ
amwa-432	125	2	transduct	transduct	NOUN
amwa-432	125	3	target	target	NOUN
amwa-432	125	4	ther	ther	ADV
amwa-432	125	5	.	.	PUNCT
amwa-432	126	1	2022;7(1):298	2022;7(1):298	X
amwa-432	126	2	.	.	PUNCT
amwa-432	127	1	3	3	X
amwa-432	127	2	.	.	X
amwa-432	127	3	parkman	parkman	PROPN
amwa-432	127	4	hp	hp	PROPN
amwa-432	127	5	,	,	PUNCT
amwa-432	127	6	rim	rim	PROPN
amwa-432	127	7	ds	ds	X
amwa-432	127	8	,	,	PUNCT
amwa-432	127	9	anolik	anolik	PROPN
amwa-432	127	10	jr	jr	PROPN
amwa-432	127	11	,	,	PUNCT
amwa-432	127	12	dadparvar	dadparvar	PROPN
amwa-432	127	13	s	s	PROPN
amwa-432	127	14	,	,	PUNCT
amwa-432	127	15	maurer	maurer	PROPN
amwa-432	127	16	ah	ah	INTJ
amwa-432	127	17	.	.	PUNCT
amwa-432	128	1	glucagonlike	glucagonlike	PROPN
amwa-432	128	2	peptide-1	peptide-1	PROPN
amwa-432	128	3	receptor	receptor	NOUN
amwa-432	128	4	agonists	agonist	NOUN
amwa-432	128	5	:	:	PUNCT
amwa-432	128	6	the	the	DET
amwa-432	128	7	good	good	NOUN
amwa-432	128	8	,	,	PUNCT
amwa-432	128	9	the	the	DET
amwa-432	128	10	bad	bad	ADJ
amwa-432	128	11	,	,	PUNCT
amwa-432	128	12	and	and	CCONJ
amwa-432	128	13	the	the	DET
amwa-432	128	14	ugly	ugly	ADJ
amwa-432	128	15	-	-	PUNCT
amwa-432	128	16	benefits	benefit	NOUN
amwa-432	128	17	for	for	ADP
amwa-432	128	18	glucose	glucose	NOUN
amwa-432	128	19	control	control	NOUN
amwa-432	128	20	and	and	CCONJ
amwa-432	128	21	weight	weight	NOUN
amwa-432	128	22	loss	loss	NOUN
amwa-432	128	23	with	with	ADP
amwa-432	128	24	16	16	NUM
amwa-432	128	25	%	%	NOUN
amwa-432	128	26	11	11	NUM
amwa-432	128	27	%	%	NOUN
amwa-432	128	28	23	23	NUM
amwa-432	128	29	%	%	NOUN
amwa-432	128	30	62	62	NUM
amwa-432	128	31	%	%	NOUN
amwa-432	128	32	57	57	NUM
amwa-432	128	33	%	%	NOUN
amwa-432	128	34	84	84	NUM
amwa-432	128	35	%	%	NOUN
amwa-432	128	36	89	89	NUM
amwa-432	128	37	%	%	NOUN
amwa-432	128	38	77	77	NUM
amwa-432	128	39	%	%	NOUN
amwa-432	128	40	38	38	NUM
amwa-432	128	41	%	%	NOUN
amwa-432	128	42	43	43	NUM
amwa-432	128	43	%	%	NOUN
amwa-432	128	44	≥≥15	≥≥15	NOUN
amwa-432	128	45	%	%	NOUN
amwa-432	128	46	≥≥15	≥≥15	NOUN
amwa-432	128	47	%	%	NOUN
amwa-432	128	48	≥≥15	≥≥15	NOUN
amwa-432	128	49	%	%	NOUN
amwa-432	128	50	≥≥15	≥≥15	NOUN
amwa-432	128	51	%	%	NOUN
amwa-432	128	52	≥≥20	≥≥20	NOUN
amwa-432	128	53	%	%	NOUN
amwa-432	128	54	nal	nal	ADJ
amwa-432	128	55	/	/	SYM
amwa-432	128	56	bu	bu	NOUN
amwa-432	128	57	liraglutide	liraglutide	NOUN
amwa-432	128	58	semaglutide	semaglutide	ADV
amwa-432	128	59	tirzepatide	tirzepatide	ADP
amwa-432	128	60	%	%	NOUN
amwa-432	128	61	effective	effective	ADJ
amwa-432	128	62	%	%	NOUN
amwa-432	128	63	ineffective	ineffective	ADJ
amwa-432	128	64	table	table	NOUN
amwa-432	128	65	2	2	NUM
amwa-432	128	66	.	.	PUNCT
amwa-432	128	67	comparison	comparison	NOUN
amwa-432	128	68	of	of	ADP
amwa-432	128	69	mean	mean	ADJ
amwa-432	128	70	heart	heart	NOUN
amwa-432	128	71	rate	rate	NOUN
amwa-432	128	72	increases	increase	NOUN
amwa-432	128	73	for	for	ADP
amwa-432	128	74	obesity	obesity	NOUN
amwa-432	128	75	drugs25,26	drugs25,26	NOUN
amwa-432	128	76	drug	drug	NOUN
amwa-432	128	77	beats	beat	NOUN
amwa-432	128	78	per	per	ADP
amwa-432	128	79	minute	minute	NOUN
amwa-432	128	80	phen	phen	NOUN
amwa-432	128	81	/	/	SYM
amwa-432	128	82	top	top	ADJ
amwa-432	128	83	0.6	0.6	NUM
amwa-432	128	84	-	-	SYM
amwa-432	128	85	1.6	1.6	NUM
amwa-432	128	86	semaglutide	semaglutide	ADJ
amwa-432	128	87	1	1	NUM
amwa-432	128	88	-	-	SYM
amwa-432	128	89	2	2	NUM
amwa-432	128	90	liraglutide	liraglutide	NOUN
amwa-432	128	91	3	3	NUM
amwa-432	128	92	-	-	SYM
amwa-432	128	93	8	8	NUM
amwa-432	128	94	tirzepatide	tirzepatide	NOUN
amwa-432	128	95	3	3	NUM
amwa-432	128	96	-	-	SYM
amwa-432	128	97	6	6	NUM
amwa-432	128	98	nal	nal	NOUN
amwa-432	128	99	/	/	SYM
amwa-432	128	100	bu	bu	ADJ
amwa-432	128	101	0.9	0.9	NUM
amwa-432	128	102	-	-	SYM
amwa-432	128	103	1.2	1.2	NUM
amwa-432	128	104	nal	nal	NOUN
amwa-432	128	105	/	/	SYM
amwa-432	128	106	bu	bu	PROPN
amwa-432	128	107	,	,	PUNCT
amwa-432	128	108	naltrexone	naltrexone	PROPN
amwa-432	128	109	with	with	ADP
amwa-432	128	110	bupropion	bupropion	NOUN
amwa-432	128	111	;	;	PUNCT
amwa-432	128	112	phen	phen	PROPN
amwa-432	128	113	/	/	SYM
amwa-432	128	114	top	top	ADJ
amwa-432	128	115	,	,	PUNCT
amwa-432	128	116	phentermine	phentermine	NOUN
amwa-432	128	117	with	with	ADP
amwa-432	128	118	topiramate	topiramate	ADJ
amwa-432	128	119	.	.	PUNCT
amwa-432	129	1	figure	figure	NOUN
amwa-432	129	2	6	6	NUM
amwa-432	129	3	.	.	PUNCT
amwa-432	129	4	percent	percent	NOUN
amwa-432	129	5	of	of	ADP
amwa-432	129	6	individuals	individual	NOUN
amwa-432	129	7	experiencing	experience	VERB
amwa-432	129	8	≥15	≥15	ADP
amwa-432	129	9	%	%	NOUN
amwa-432	129	10	or	or	CCONJ
amwa-432	129	11	≥20	≥20	NOUN
amwa-432	129	12	%	%	NOUN
amwa-432	129	13	weight	weight	NOUN
amwa-432	129	14	reduction	reduction	NOUN
amwa-432	129	15	from	from	ADP
amwa-432	129	16	drug	drug	NOUN
amwa-432	129	17	treatment	treatment	NOUN
amwa-432	129	18	during	during	ADP
amwa-432	129	19	clinical	clinical	ADJ
amwa-432	129	20	trial	trial	NOUN
amwa-432	129	21	testing.17,21	testing.17,21	NOUN
amwa-432	129	22	nal	nal	PROPN
amwa-432	129	23	/	/	SYM
amwa-432	129	24	bu	bu	PROPN
amwa-432	129	25	,	,	PUNCT
amwa-432	129	26	naltrexone	naltrexone	PROPN
amwa-432	129	27	with	with	ADP
amwa-432	129	28	bupropion	bupropion	NOUN
amwa-432	129	29	.	.	PUNCT
amwa-432	129	30	http://www.amwajournal.org	http://www.amwajournal.org	X
amwa-432	130	1	amwajournal.org	amwajournal.org	X
amwa-432	130	2	41incretin	41incretin	NUM
amwa-432	130	3	drug	drug	NOUN
amwa-432	130	4	revolution	revolution	NOUN
amwa-432	130	5	:	:	PUNCT
amwa-432	130	6	the	the	DET
amwa-432	130	7	challenges	challenge	NOUN
amwa-432	130	8	of	of	ADP
amwa-432	130	9	hope	hope	NOUN
amwa-432	130	10	side	side	NOUN
amwa-432	130	11	effects	effect	NOUN
amwa-432	130	12	of	of	ADP
amwa-432	130	13	delaying	delay	VERB
amwa-432	130	14	gastric	gastric	ADJ
amwa-432	130	15	emptying	emptying	NOUN
amwa-432	130	16	.	.	PUNCT
amwa-432	131	1	j	j	PROPN
amwa-432	131	2	nucl	nucl	PROPN
amwa-432	131	3	med	med	PROPN
amwa-432	131	4	technol	technol	NOUN
amwa-432	131	5	.	.	PUNCT
amwa-432	131	6	2024;52(1):3	2024;52(1):3	NUM
amwa-432	131	7	-	-	SYM
amwa-432	131	8	7	7	NUM
amwa-432	131	9	.	.	NOUN
amwa-432	131	10	4	4	NUM
amwa-432	131	11	.	.	X
amwa-432	131	12	elmaleh	elmaleh	NOUN
amwa-432	131	13	-	-	PUNCT
amwa-432	131	14	sachs	sachs	PROPN
amwa-432	131	15	a	a	PRON
amwa-432	131	16	,	,	PUNCT
amwa-432	131	17	schwartz	schwartz	PROPN
amwa-432	131	18	jl	jl	PROPN
amwa-432	131	19	,	,	PUNCT
amwa-432	131	20	bramante	bramante	PROPN
amwa-432	131	21	ct	ct	PROPN
amwa-432	131	22	,	,	PUNCT
amwa-432	131	23	nicklas	nicklas	PROPN
amwa-432	131	24	jm	jm	PROPN
amwa-432	131	25	,	,	PUNCT
amwa-432	131	26	gudzune	gudzune	PROPN
amwa-432	131	27	ka	ka	PROPN
amwa-432	131	28	,	,	PUNCT
amwa-432	131	29	jay	jay	PROPN
amwa-432	131	30	m.	m.	NOUN
amwa-432	131	31	obesity	obesity	NOUN
amwa-432	131	32	management	management	NOUN
amwa-432	131	33	in	in	ADP
amwa-432	131	34	adults	adult	NOUN
amwa-432	131	35	:	:	PUNCT
amwa-432	131	36	a	a	DET
amwa-432	131	37	review	review	NOUN
amwa-432	131	38	.	.	PUNCT
amwa-432	132	1	jama	jama	PROPN
amwa-432	132	2	.	.	PUNCT
amwa-432	133	1	2023	2023	NUM
amwa-432	133	2	;	;	PUNCT
amwa-432	134	1	330(20):2000	330(20):2000	PROPN
amwa-432	134	2	-	-	SYM
amwa-432	134	3	2015	2015	NUM
amwa-432	134	4	.	.	PUNCT
amwa-432	135	1	5	5	X
amwa-432	135	2	.	.	X
amwa-432	135	3	lister	lister	PROPN
amwa-432	135	4	nb	nb	PROPN
amwa-432	135	5	,	,	PUNCT
amwa-432	135	6	baur	baur	PROPN
amwa-432	135	7	la	la	PROPN
amwa-432	135	8	,	,	PUNCT
amwa-432	135	9	felix	felix	PROPN
amwa-432	135	10	jf	jf	PROPN
amwa-432	135	11	,	,	PUNCT
amwa-432	135	12	et	et	PROPN
amwa-432	135	13	al	al	PROPN
amwa-432	135	14	.	.	PROPN
amwa-432	135	15	child	child	NOUN
amwa-432	135	16	and	and	CCONJ
amwa-432	135	17	adolescent	adolescent	ADJ
amwa-432	135	18	obesity	obesity	NOUN
amwa-432	135	19	.	.	PUNCT
amwa-432	136	1	nat	nat	PROPN
amwa-432	136	2	rev	rev	VERB
amwa-432	136	3	dis	dis	PROPN
amwa-432	136	4	primers	primer	NOUN
amwa-432	136	5	.	.	PUNCT
amwa-432	137	1	2023;9(1):24	2023;9(1):24	NUM
amwa-432	137	2	.	.	NOUN
amwa-432	137	3	6	6	NUM
amwa-432	137	4	.	.	X
amwa-432	137	5	bosy	bosy	PROPN
amwa-432	137	6	-	-	PUNCT
amwa-432	137	7	westphal	westphal	PROPN
amwa-432	137	8	a	a	PROPN
amwa-432	137	9	,	,	PUNCT
amwa-432	137	10	müller	müller	PROPN
amwa-432	137	11	mj	mj	PROPN
amwa-432	137	12	.	.	PUNCT
amwa-432	137	13	diagnosis	diagnosis	NOUN
amwa-432	137	14	of	of	ADP
amwa-432	137	15	obesity	obesity	NOUN
amwa-432	137	16	based	base	VERB
amwa-432	137	17	on	on	ADP
amwa-432	137	18	body	body	NOUN
amwa-432	137	19	composition	composition	NOUN
amwa-432	137	20	-	-	PUNCT
amwa-432	137	21	associated	associate	VERB
amwa-432	137	22	health	health	NOUN
amwa-432	137	23	risks	risk	NOUN
amwa-432	137	24	–	–	PUNCT
amwa-432	137	25	time	time	NOUN
amwa-432	137	26	for	for	ADP
amwa-432	137	27	a	a	DET
amwa-432	137	28	change	change	NOUN
amwa-432	137	29	in	in	ADP
amwa-432	137	30	paradigm	paradigm	NOUN
amwa-432	137	31	.	.	PUNCT
amwa-432	138	1	obes	obe	NOUN
amwa-432	138	2	rev	rev	VERB
amwa-432	138	3	.	.	PUNCT
amwa-432	138	4	2021;22	2021;22	NUM
amwa-432	138	5	suppl	suppl	ADJ
amwa-432	138	6	2	2	NUM
amwa-432	138	7	:	:	PUNCT
amwa-432	138	8	e13190	e13190	ADJ
amwa-432	138	9	.	.	PROPN
amwa-432	138	10	7	7	X
amwa-432	138	11	.	.	X
amwa-432	138	12	volger	volger	NOUN
amwa-432	138	13	s	s	PROPN
amwa-432	138	14	,	,	PUNCT
amwa-432	138	15	vetter	vetter	PROPN
amwa-432	138	16	ml	ml	PROPN
amwa-432	138	17	,	,	PUNCT
amwa-432	138	18	dougherty	dougherty	PROPN
amwa-432	138	19	m	m	PROPN
amwa-432	138	20	,	,	PUNCT
amwa-432	138	21	et	et	PROPN
amwa-432	138	22	al	al	PROPN
amwa-432	139	1	.	.	PUNCT
amwa-432	139	2	patients	patient	NOUN
amwa-432	139	3	’	'	PUNCT
amwa-432	140	1	preferred	preferred	ADJ
amwa-432	140	2	terms	term	NOUN
amwa-432	140	3	for	for	ADP
amwa-432	140	4	describing	describe	VERB
amwa-432	140	5	their	their	PRON
amwa-432	140	6	excess	excess	ADJ
amwa-432	140	7	weight	weight	NOUN
amwa-432	140	8	:	:	PUNCT
amwa-432	140	9	discussing	discuss	VERB
amwa-432	140	10	obesity	obesity	NOUN
amwa-432	140	11	in	in	ADP
amwa-432	140	12	clinical	clinical	ADJ
amwa-432	140	13	practice	practice	NOUN
amwa-432	140	14	.	.	PUNCT
amwa-432	141	1	obesity	obesity	NOUN
amwa-432	141	2	(	(	PUNCT
amwa-432	141	3	silver	silver	ADJ
amwa-432	141	4	spring	spring	NOUN
amwa-432	141	5	)	)	PUNCT
amwa-432	141	6	.	.	PUNCT
amwa-432	142	1	2012;20(1):147	2012;20(1):147	NUM
amwa-432	142	2	-	-	PUNCT
amwa-432	142	3	150	150	NUM
amwa-432	142	4	.	.	NOUN
amwa-432	142	5	8	8	NUM
amwa-432	142	6	.	.	PUNCT
amwa-432	142	7	rubino	rubino	PROPN
amwa-432	142	8	f	f	PROPN
amwa-432	142	9	,	,	PUNCT
amwa-432	142	10	batterham	batterham	PROPN
amwa-432	142	11	rl	rl	PROPN
amwa-432	142	12	,	,	PUNCT
amwa-432	142	13	koch	koch	PROPN
amwa-432	142	14	m	m	PROPN
amwa-432	142	15	,	,	PUNCT
amwa-432	142	16	et	et	PROPN
amwa-432	142	17	al	al	PROPN
amwa-432	142	18	.	.	PUNCT
amwa-432	143	1	lancet	lancet	PROPN
amwa-432	143	2	diabetes	diabetes	PROPN
amwa-432	143	3	&	&	CCONJ
amwa-432	143	4	endocrinology	endocrinology	PROPN
amwa-432	143	5	commission	commission	PROPN
amwa-432	143	6	on	on	ADP
amwa-432	143	7	the	the	DET
amwa-432	143	8	definition	definition	NOUN
amwa-432	143	9	and	and	CCONJ
amwa-432	143	10	diagnosis	diagnosis	NOUN
amwa-432	143	11	of	of	ADP
amwa-432	143	12	clinical	clinical	ADJ
amwa-432	143	13	obesity	obesity	NOUN
amwa-432	143	14	.	.	PUNCT
amwa-432	144	1	lancet	lancet	NOUN
amwa-432	144	2	diabetes	diabetes	NOUN
amwa-432	144	3	endocrinol	endocrinol	NOUN
amwa-432	144	4	.	.	PUNCT
amwa-432	145	1	2023;11(4):226	2023;11(4):226	NUM
amwa-432	145	2	-	-	SYM
amwa-432	145	3	228	228	NUM
amwa-432	145	4	.	.	PUNCT
amwa-432	146	1	9	9	NUM
amwa-432	146	2	.	.	X
amwa-432	146	3	tanne	tanne	PROPN
amwa-432	146	4	jh	jh	PROPN
amwa-432	146	5	.	.	PUNCT
amwa-432	147	1	obesity	obesity	NOUN
amwa-432	147	2	:	:	PUNCT
amwa-432	147	3	avoid	avoid	VERB
amwa-432	147	4	using	use	VERB
amwa-432	147	5	bmi	bmi	NOUN
amwa-432	147	6	alone	alone	ADV
amwa-432	147	7	when	when	SCONJ
amwa-432	147	8	evaluating	evaluate	VERB
amwa-432	147	9	patients	patient	NOUN
amwa-432	147	10	,	,	PUNCT
amwa-432	147	11	say	say	VERB
amwa-432	147	12	us	us	PROPN
amwa-432	147	13	doctors	doctor	NOUN
amwa-432	147	14	’	’	PART
amwa-432	147	15	leaders	leader	NOUN
amwa-432	147	16	.	.	PUNCT
amwa-432	148	1	bmj	bmj	PROPN
amwa-432	148	2	.	.	PUNCT
amwa-432	149	1	2023;381:1400	2023;381:1400	NUM
amwa-432	149	2	.	.	PUNCT
amwa-432	150	1	10	10	NUM
amwa-432	150	2	.	.	X
amwa-432	150	3	swinburn	swinburn	PROPN
amwa-432	150	4	ba	ba	PROPN
amwa-432	150	5	,	,	PUNCT
amwa-432	150	6	kraak	kraak	PROPN
amwa-432	150	7	vi	vi	PROPN
amwa-432	150	8	,	,	PUNCT
amwa-432	150	9	allender	allender	NOUN
amwa-432	150	10	s	s	PROPN
amwa-432	150	11	,	,	PUNCT
amwa-432	150	12	et	et	PROPN
amwa-432	150	13	al	al	PROPN
amwa-432	150	14	.	.	PUNCT
amwa-432	151	1	the	the	DET
amwa-432	151	2	global	global	ADJ
amwa-432	151	3	syndemic	syndemic	NOUN
amwa-432	151	4	of	of	ADP
amwa-432	151	5	obesity	obesity	NOUN
amwa-432	151	6	,	,	PUNCT
amwa-432	151	7	undernutrition	undernutrition	NOUN
amwa-432	151	8	,	,	PUNCT
amwa-432	151	9	and	and	CCONJ
amwa-432	151	10	climate	climate	NOUN
amwa-432	151	11	change	change	NOUN
amwa-432	151	12	:	:	PUNCT
amwa-432	151	13	the	the	DET
amwa-432	151	14	lancet	lancet	PROPN
amwa-432	151	15	commission	commission	PROPN
amwa-432	151	16	report	report	NOUN
amwa-432	151	17	.	.	PUNCT
amwa-432	152	1	lancet	lancet	VERB
amwa-432	152	2	.	.	PUNCT
amwa-432	153	1	2019;393(10173):791	2019;393(10173):791	NUM
amwa-432	153	2	-	-	SYM
amwa-432	153	3	846	846	NUM
amwa-432	153	4	.	.	PUNCT
amwa-432	154	1	11	11	NUM
amwa-432	154	2	.	.	PUNCT
amwa-432	155	1	adult	adult	NOUN
amwa-432	155	2	obesity	obesity	NOUN
amwa-432	155	3	facts	fact	NOUN
amwa-432	155	4	.	.	PUNCT
amwa-432	156	1	centers	center	NOUN
amwa-432	156	2	for	for	ADP
amwa-432	156	3	disease	disease	NOUN
amwa-432	156	4	control	control	NOUN
amwa-432	156	5	and	and	CCONJ
amwa-432	156	6	prevention	prevention	NOUN
amwa-432	156	7	.	.	PUNCT
amwa-432	157	1	accessed	access	VERB
amwa-432	157	2	december	december	PROPN
amwa-432	157	3	3	3	NUM
amwa-432	157	4	,	,	PUNCT
amwa-432	157	5	2024	2024	NUM
amwa-432	157	6	.	.	PUNCT
amwa-432	158	1	https://www.cdc.gov/obesity/adultobesity-facts/index.html	https://www.cdc.gov/obesity/adultobesity-facts/index.html	PROPN
amwa-432	158	2	12	12	NUM
amwa-432	158	3	.	.	PUNCT
amwa-432	159	1	childhood	childhood	NOUN
amwa-432	159	2	obesity	obesity	NOUN
amwa-432	159	3	facts	fact	NOUN
amwa-432	159	4	.	.	PUNCT
amwa-432	160	1	centers	center	NOUN
amwa-432	160	2	for	for	ADP
amwa-432	160	3	disease	disease	NOUN
amwa-432	160	4	control	control	NOUN
amwa-432	160	5	and	and	CCONJ
amwa-432	160	6	prevention	prevention	NOUN
amwa-432	160	7	.	.	PUNCT
amwa-432	161	1	accessed	access	VERB
amwa-432	161	2	december	december	PROPN
amwa-432	161	3	3	3	NUM
amwa-432	161	4	,	,	PUNCT
amwa-432	161	5	2024	2024	NUM
amwa-432	161	6	.	.	PUNCT
amwa-432	162	1	https://www.cdc.gov/	https://www.cdc.gov/	PROPN
amwa-432	162	2	obesity	obesity	NOUN
amwa-432	162	3	/	/	SYM
amwa-432	162	4	childhood	childhood	NOUN
amwa-432	162	5	-	-	PUNCT
amwa-432	162	6	obesity	obesity	NOUN
amwa-432	162	7	-	-	PUNCT
amwa-432	162	8	facts	fact	NOUN
amwa-432	162	9	/	/	SYM
amwa-432	162	10	childhood	childhood	NOUN
amwa-432	162	11	-	-	PUNCT
amwa-432	162	12	obesity	obesity	NOUN
amwa-432	162	13	-	-	PUNCT
amwa-432	162	14	facts.html	facts.html	PROPN
amwa-432	162	15	13	13	NUM
amwa-432	162	16	.	.	PUNCT
amwa-432	163	1	johnson	johnson	PROPN
amwa-432	163	2	-	-	PUNCT
amwa-432	163	3	mann	mann	PROPN
amwa-432	163	4	cn	cn	PROPN
amwa-432	163	5	,	,	PUNCT
amwa-432	163	6	cupka	cupka	PROPN
amwa-432	163	7	js	js	PROPN
amwa-432	163	8	,	,	PUNCT
amwa-432	163	9	ro	ro	PROPN
amwa-432	163	10	a	a	X
amwa-432	163	11	,	,	PUNCT
amwa-432	163	12	et	et	PROPN
amwa-432	163	13	al	al	PROPN
amwa-432	163	14	.	.	PUNCT
amwa-432	164	1	a	a	DET
amwa-432	164	2	systematic	systematic	ADJ
amwa-432	164	3	review	review	NOUN
amwa-432	164	4	on	on	ADP
amwa-432	164	5	participant	participant	ADJ
amwa-432	164	6	diversity	diversity	NOUN
amwa-432	164	7	in	in	ADP
amwa-432	164	8	clinical	clinical	ADJ
amwa-432	164	9	trials	trial	NOUN
amwa-432	164	10	–	–	PUNCT
amwa-432	164	11	have	have	AUX
amwa-432	164	12	we	we	PRON
amwa-432	164	13	made	make	VERB
amwa-432	164	14	progress	progress	NOUN
amwa-432	164	15	for	for	ADP
amwa-432	164	16	the	the	DET
amwa-432	164	17	management	management	NOUN
amwa-432	164	18	of	of	ADP
amwa-432	164	19	obesity	obesity	NOUN
amwa-432	164	20	and	and	CCONJ
amwa-432	164	21	its	its	PRON
amwa-432	164	22	metabolic	metabolic	NOUN
amwa-432	164	23	sequelae	sequelae	NOUN
amwa-432	164	24	in	in	ADP
amwa-432	164	25	diet	diet	NOUN
amwa-432	164	26	,	,	PUNCT
amwa-432	164	27	drug	drug	NOUN
amwa-432	164	28	,	,	PUNCT
amwa-432	164	29	and	and	CCONJ
amwa-432	164	30	surgical	surgical	ADJ
amwa-432	164	31	trials	trial	NOUN
amwa-432	164	32	.	.	PUNCT
amwa-432	165	1	j	j	PROPN
amwa-432	165	2	racial	racial	ADJ
amwa-432	165	3	ethn	ethn	NOUN
amwa-432	165	4	health	health	NOUN
amwa-432	165	5	disparities	disparity	NOUN
amwa-432	165	6	.	.	PUNCT
amwa-432	166	1	2023;10(6):3140	2023;10(6):3140	NUM
amwa-432	166	2	-	-	SYM
amwa-432	166	3	3149	3149	NUM
amwa-432	166	4	.	.	PUNCT
amwa-432	167	1	14	14	NUM
amwa-432	167	2	.	.	PUNCT
amwa-432	168	1	gaskin	gaskin	PROPN
amwa-432	168	2	cj	cj	PROPN
amwa-432	168	3	,	,	PUNCT
amwa-432	168	4	cooper	cooper	PROPN
amwa-432	168	5	k	k	PROPN
amwa-432	168	6	,	,	PUNCT
amwa-432	168	7	stephens	stephens	PROPN
amwa-432	168	8	ld	ld	PROPN
amwa-432	168	9	,	,	PUNCT
amwa-432	168	10	peeters	peeter	NOUN
amwa-432	168	11	a	a	PRON
amwa-432	168	12	,	,	PUNCT
amwa-432	168	13	salmon	salmon	PROPN
amwa-432	168	14	j	j	PROPN
amwa-432	168	15	,	,	PUNCT
amwa-432	168	16	porter	porter	NOUN
amwa-432	168	17	j.	j.	PROPN
amwa-432	168	18	clinical	clinical	PROPN
amwa-432	168	19	practice	practice	NOUN
amwa-432	168	20	guidelines	guideline	NOUN
amwa-432	168	21	for	for	ADP
amwa-432	168	22	the	the	DET
amwa-432	168	23	management	management	NOUN
amwa-432	168	24	of	of	ADP
amwa-432	168	25	overweight	overweight	NOUN
amwa-432	168	26	and	and	CCONJ
amwa-432	168	27	obesity	obesity	NOUN
amwa-432	168	28	published	publish	VERB
amwa-432	168	29	internationally	internationally	ADV
amwa-432	168	30	:	:	PUNCT
amwa-432	168	31	a	a	DET
amwa-432	168	32	scoping	scope	VERB
amwa-432	168	33	review	review	NOUN
amwa-432	168	34	.	.	PUNCT
amwa-432	169	1	obes	obes	PROPN
amwa-432	169	2	rev	rev	VERB
amwa-432	169	3	.	.	PUNCT
amwa-432	170	1	2024;25(5):e13700	2024;25(5):e13700	NUM
amwa-432	170	2	.	.	NOUN
amwa-432	170	3	15	15	NUM
amwa-432	170	4	.	.	PUNCT
amwa-432	171	1	d’ávila	d’ávila	PROPN
amwa-432	171	2	m	m	PROPN
amwa-432	171	3	,	,	PUNCT
amwa-432	171	4	hall	hall	PROPN
amwa-432	171	5	s	s	PROPN
amwa-432	171	6	,	,	PUNCT
amwa-432	171	7	horvath	horvath	PROPN
amwa-432	171	8	tl	tl	PROPN
amwa-432	171	9	.	.	PROPN
amwa-432	171	10	glp-1	glp-1	SYM
amwa-432	171	11	,	,	PUNCT
amwa-432	171	12	gip	gip	NOUN
amwa-432	171	13	,	,	PUNCT
amwa-432	171	14	and	and	CCONJ
amwa-432	171	15	glucagon	glucagon	NOUN
amwa-432	171	16	agonists	agonist	NOUN
amwa-432	171	17	for	for	ADP
amwa-432	171	18	obesity	obesity	NOUN
amwa-432	171	19	treatment	treatment	NOUN
amwa-432	171	20	:	:	PUNCT
amwa-432	171	21	a	a	DET
amwa-432	171	22	hunger	hunger	NOUN
amwa-432	171	23	perspective	perspective	NOUN
amwa-432	171	24	.	.	PUNCT
amwa-432	172	1	endocrinology	endocrinology	NOUN
amwa-432	172	2	.	.	PUNCT
amwa-432	173	1	2024;165(11):bqae128	2024;165(11):bqae128	NUM
amwa-432	173	2	.	.	PUNCT
amwa-432	174	1	16	16	NUM
amwa-432	174	2	.	.	PUNCT
amwa-432	174	3	gudzune	gudzune	PROPN
amwa-432	174	4	ka	ka	PROPN
amwa-432	174	5	,	,	PUNCT
amwa-432	174	6	kushner	kushner	PROPN
amwa-432	174	7	rf	rf	PROPN
amwa-432	174	8	.	.	PUNCT
amwa-432	174	9	medications	medication	NOUN
amwa-432	174	10	for	for	ADP
amwa-432	174	11	obesity	obesity	NOUN
amwa-432	174	12	:	:	PUNCT
amwa-432	174	13	a	a	DET
amwa-432	174	14	review	review	NOUN
amwa-432	174	15	.	.	PUNCT
amwa-432	175	1	jama	jama	PROPN
amwa-432	175	2	.	.	PUNCT
amwa-432	176	1	2024;332(7):571	2024;332(7):571	NUM
amwa-432	176	2	-	-	SYM
amwa-432	176	3	584	584	NUM
amwa-432	176	4	.	.	NOUN
amwa-432	177	1	17	17	NUM
amwa-432	177	2	.	.	PUNCT
amwa-432	177	3	chakhtoura	chakhtoura	PROPN
amwa-432	177	4	m	m	PROPN
amwa-432	177	5	,	,	PUNCT
amwa-432	177	6	haber	haber	PROPN
amwa-432	177	7	r	r	PROPN
amwa-432	177	8	,	,	PUNCT
amwa-432	177	9	ghezzawi	ghezzawi	NOUN
amwa-432	177	10	m	m	PRON
amwa-432	177	11	,	,	PUNCT
amwa-432	177	12	rhayem	rhayem	VERB
amwa-432	177	13	c	c	X
amwa-432	177	14	,	,	PUNCT
amwa-432	177	15	tcheroyan	tcheroyan	VERB
amwa-432	177	16	r	r	PROPN
amwa-432	177	17	,	,	PUNCT
amwa-432	177	18	mantzoros	mantzoros	PROPN
amwa-432	177	19	cs	cs	PROPN
amwa-432	177	20	.	.	PROPN
amwa-432	177	21	pharmacotherapy	pharmacotherapy	NOUN
amwa-432	177	22	of	of	ADP
amwa-432	177	23	obesity	obesity	NOUN
amwa-432	177	24	:	:	PUNCT
amwa-432	177	25	an	an	DET
amwa-432	177	26	update	update	NOUN
amwa-432	177	27	on	on	ADP
amwa-432	177	28	the	the	DET
amwa-432	177	29	available	available	ADJ
amwa-432	177	30	medications	medication	NOUN
amwa-432	177	31	and	and	CCONJ
amwa-432	177	32	drugs	drug	NOUN
amwa-432	177	33	under	under	ADP
amwa-432	177	34	investigation	investigation	NOUN
amwa-432	177	35	.	.	PUNCT
amwa-432	178	1	eclinicalmedicine	eclinicalmedicine	PROPN
amwa-432	178	2	.	.	PUNCT
amwa-432	179	1	2023;58:101882	2023;58:101882	NUM
amwa-432	179	2	.	.	NOUN
amwa-432	179	3	18	18	NUM
amwa-432	179	4	.	.	PUNCT
amwa-432	180	1	khera	khera	NOUN
amwa-432	180	2	r	r	PROPN
amwa-432	180	3	,	,	PUNCT
amwa-432	180	4	murad	murad	PROPN
amwa-432	180	5	mh	mh	PROPN
amwa-432	180	6	,	,	PUNCT
amwa-432	180	7	chandar	chandar	PROPN
amwa-432	180	8	ak	ak	PROPN
amwa-432	180	9	,	,	PUNCT
amwa-432	180	10	et	et	PROPN
amwa-432	180	11	al	al	PROPN
amwa-432	180	12	.	.	PROPN
amwa-432	180	13	association	association	PROPN
amwa-432	180	14	of	of	ADP
amwa-432	180	15	pharmacological	pharmacological	ADJ
amwa-432	180	16	treatments	treatment	NOUN
amwa-432	180	17	for	for	ADP
amwa-432	180	18	obesity	obesity	NOUN
amwa-432	180	19	with	with	ADP
amwa-432	180	20	weight	weight	NOUN
amwa-432	180	21	loss	loss	NOUN
amwa-432	180	22	and	and	CCONJ
amwa-432	180	23	adverse	adverse	ADJ
amwa-432	180	24	events	event	NOUN
amwa-432	180	25	:	:	PUNCT
amwa-432	180	26	a	a	DET
amwa-432	180	27	systematic	systematic	ADJ
amwa-432	180	28	review	review	NOUN
amwa-432	180	29	and	and	CCONJ
amwa-432	180	30	meta	meta	ADJ
amwa-432	180	31	-	-	PUNCT
amwa-432	180	32	analysis	analysis	NOUN
amwa-432	180	33	.	.	PUNCT
amwa-432	181	1	jama	jama	NOUN
amwa-432	181	2	.	.	PUNCT
amwa-432	182	1	2016;315(22):2424	2016;315(22):2424	X
amwa-432	182	2	-	-	SYM
amwa-432	182	3	2434	2434	NUM
amwa-432	182	4	.	.	PUNCT
amwa-432	183	1	19	19	NUM
amwa-432	183	2	.	.	X
amwa-432	183	3	yao	yao	PROPN
amwa-432	183	4	h	h	PROPN
amwa-432	183	5	,	,	PUNCT
amwa-432	183	6	zhang	zhang	PROPN
amwa-432	183	7	a	a	PROPN
amwa-432	183	8	,	,	PUNCT
amwa-432	183	9	li	li	PROPN
amwa-432	183	10	d	d	PROPN
amwa-432	183	11	,	,	PUNCT
amwa-432	183	12	et	et	PROPN
amwa-432	183	13	al	al	PROPN
amwa-432	183	14	.	.	PROPN
amwa-432	183	15	comparative	comparative	ADJ
amwa-432	183	16	effectiveness	effectiveness	NOUN
amwa-432	183	17	of	of	ADP
amwa-432	183	18	glp-1	glp-1	NOUN
amwa-432	183	19	receptor	receptor	NOUN
amwa-432	183	20	agonists	agonist	NOUN
amwa-432	183	21	on	on	ADP
amwa-432	183	22	glycaemic	glycaemic	ADJ
amwa-432	183	23	control	control	NOUN
amwa-432	183	24	,	,	PUNCT
amwa-432	183	25	body	body	NOUN
amwa-432	183	26	weight	weight	NOUN
amwa-432	183	27	,	,	PUNCT
amwa-432	183	28	and	and	CCONJ
amwa-432	183	29	lipid	lipid	NOUN
amwa-432	183	30	profile	profile	NOUN
amwa-432	183	31	for	for	ADP
amwa-432	183	32	type	type	NOUN
amwa-432	183	33	2	2	NUM
amwa-432	183	34	diabetes	diabetes	NOUN
amwa-432	183	35	:	:	PUNCT
amwa-432	183	36	systematic	systematic	ADJ
amwa-432	183	37	review	review	NOUN
amwa-432	183	38	and	and	CCONJ
amwa-432	183	39	network	network	NOUN
amwa-432	183	40	metaanalysis	metaanalysis	NOUN
amwa-432	183	41	.	.	PUNCT
amwa-432	184	1	bmj	bmj	PROPN
amwa-432	184	2	.	.	PUNCT
amwa-432	185	1	2024;384	2024;384	NUM
amwa-432	185	2	:	:	PUNCT
amwa-432	186	1	e076410	e076410	PROPN
amwa-432	186	2	.	.	PROPN
amwa-432	187	1	20	20	NUM
amwa-432	187	2	.	.	PUNCT
amwa-432	188	1	gan	gan	PROPN
amwa-432	188	2	h	h	PROPN
amwa-432	188	3	-	-	PUNCT
amwa-432	188	4	w	w	NOUN
amwa-432	188	5	,	,	PUNCT
amwa-432	188	6	cerbone	cerbone	NOUN
amwa-432	188	7	m	m	PROPN
amwa-432	188	8	,	,	PUNCT
amwa-432	188	9	dattani	dattani	PROPN
amwa-432	188	10	mt	mt	PROPN
amwa-432	188	11	.	.	PROPN
amwa-432	189	1	appetiteand	appetiteand	ADV
amwa-432	189	2	weightregulating	weightregulate	VERB
amwa-432	189	3	neuroendocrine	neuroendocrine	ADJ
amwa-432	189	4	circuitry	circuitry	NOUN
amwa-432	189	5	in	in	ADP
amwa-432	189	6	hypothalamic	hypothalamic	ADJ
amwa-432	189	7	obesity	obesity	NOUN
amwa-432	189	8	.	.	PUNCT
amwa-432	190	1	endocr	endocr	PROPN
amwa-432	190	2	rev	rev	PROPN
amwa-432	190	3	.	.	PROPN
amwa-432	191	1	2024;45(3):309	2024;45(3):309	NUM
amwa-432	191	2	-	-	PUNCT
amwa-432	191	3	342	342	NUM
amwa-432	191	4	.	.	PUNCT
amwa-432	192	1	21	21	NUM
amwa-432	192	2	.	.	PUNCT
amwa-432	193	1	henderson	henderson	PROPN
amwa-432	193	2	k	k	PROPN
amwa-432	193	3	,	,	PUNCT
amwa-432	193	4	lewis	lewis	PROPN
amwa-432	193	5	,	,	PUNCT
amwa-432	193	6	sloan	sloan	PROPN
amwa-432	193	7	ce	ce	PROPN
amwa-432	193	8	,	,	PUNCT
amwa-432	193	9	bessesen	bessesen	PROPN
amwa-432	193	10	dh	dh	PROPN
amwa-432	193	11	,	,	PUNCT
amwa-432	193	12	arterburn	arterburn	VERB
amwa-432	193	13	d.	d.	PROPN
amwa-432	193	14	effectiveness	effectiveness	PROPN
amwa-432	193	15	and	and	CCONJ
amwa-432	193	16	safety	safety	NOUN
amwa-432	193	17	of	of	ADP
amwa-432	193	18	drugs	drug	NOUN
amwa-432	193	19	for	for	ADP
amwa-432	193	20	obesity	obesity	NOUN
amwa-432	193	21	.	.	PUNCT
amwa-432	194	1	bmj	bmj	PROPN
amwa-432	194	2	.	.	PUNCT
amwa-432	195	1	2024;384	2024;384	NUM
amwa-432	195	2	:	:	PUNCT
amwa-432	195	3	e072686	e072686	NOUN
amwa-432	195	4	.	.	NOUN
amwa-432	195	5	22	22	NUM
amwa-432	195	6	.	.	PUNCT
amwa-432	196	1	jastreboff	jastreboff	PROPN
amwa-432	196	2	am	be	AUX
amwa-432	196	3	,	,	PUNCT
amwa-432	196	4	aronne	aronne	PROPN
amwa-432	196	5	lj	lj	PROPN
amwa-432	196	6	,	,	PUNCT
amwa-432	196	7	ahmad	ahmad	PROPN
amwa-432	196	8	nn	nn	PROPN
amwa-432	196	9	,	,	PUNCT
amwa-432	196	10	et	et	PROPN
amwa-432	196	11	al	al	PROPN
amwa-432	196	12	.	.	PROPN
amwa-432	197	1	tirzepatide	tirzepatide	NOUN
amwa-432	197	2	once	once	ADV
amwa-432	197	3	weekly	weekly	ADV
amwa-432	197	4	for	for	ADP
amwa-432	197	5	the	the	DET
amwa-432	197	6	treatment	treatment	NOUN
amwa-432	197	7	of	of	ADP
amwa-432	197	8	obesity	obesity	NOUN
amwa-432	197	9	.	.	PUNCT
amwa-432	198	1	n	n	PROPN
amwa-432	198	2	engl	engl	PROPN
amwa-432	198	3	j	j	PROPN
amwa-432	198	4	med	med	PROPN
amwa-432	198	5	.	.	PUNCT
amwa-432	199	1	2022;387(3	2022;387(3	NUM
amwa-432	199	2	):	):	PUNCT
amwa-432	199	3	205	205	NUM
amwa-432	199	4	-	-	SYM
amwa-432	199	5	216	216	NUM
amwa-432	199	6	.	.	PUNCT
amwa-432	200	1	23	23	NUM
amwa-432	200	2	.	.	X
amwa-432	201	1	lingvay	lingvay	PROPN
amwa-432	201	2	i	i	PRON
amwa-432	201	3	,	,	PUNCT
amwa-432	201	4	sumithran	sumithran	PROPN
amwa-432	201	5	p	p	X
amwa-432	201	6	,	,	PUNCT
amwa-432	201	7	le	le	X
amwa-432	201	8	roux	roux	NOUN
amwa-432	201	9	cw	cw	PROPN
amwa-432	201	10	,	,	PUNCT
amwa-432	201	11	cohen	cohen	PROPN
amwa-432	201	12	rv	rv	PROPN
amwa-432	201	13	.	.	PUNCT
amwa-432	202	1	there	there	PRON
amwa-432	202	2	is	be	VERB
amwa-432	202	3	no	no	DET
amwa-432	202	4	magic	magic	ADJ
amwa-432	202	5	bullet	bullet	NOUN
amwa-432	202	6	for	for	ADP
amwa-432	202	7	obesity	obesity	NOUN
amwa-432	202	8	.	.	PUNCT
amwa-432	203	1	lancet	lancet	NOUN
amwa-432	203	2	diabetes	diabetes	NOUN
amwa-432	203	3	endocrinol	endocrinol	NOUN
amwa-432	203	4	.	.	PUNCT
amwa-432	204	1	2023;11(8):541	2023;11(8):541	NUM
amwa-432	204	2	.	.	PUNCT
amwa-432	205	1	24	24	NUM
amwa-432	205	2	.	.	X
amwa-432	206	1	dietrich	dietrich	PROPN
amwa-432	206	2	mo	mo	PROPN
amwa-432	206	3	,	,	PUNCT
amwa-432	206	4	horvath	horvath	PROPN
amwa-432	206	5	tl	tl	PROPN
amwa-432	206	6	.	.	PUNCT
amwa-432	206	7	limitations	limitation	NOUN
amwa-432	206	8	in	in	ADP
amwa-432	206	9	anti	anti	ADJ
amwa-432	206	10	-	-	ADJ
amwa-432	206	11	obesity	obesity	ADJ
amwa-432	206	12	drug	drug	NOUN
amwa-432	206	13	development	development	NOUN
amwa-432	206	14	:	:	PUNCT
amwa-432	206	15	the	the	DET
amwa-432	206	16	critical	critical	ADJ
amwa-432	206	17	role	role	NOUN
amwa-432	206	18	of	of	ADP
amwa-432	206	19	hunger	hunger	NOUN
amwa-432	206	20	-	-	PUNCT
amwa-432	206	21	promoting	promote	VERB
amwa-432	206	22	neurons	neuron	NOUN
amwa-432	206	23	.	.	PUNCT
amwa-432	207	1	nat	nat	PROPN
amwa-432	207	2	rev	rev	VERB
amwa-432	207	3	drug	drug	NOUN
amwa-432	207	4	discov	discov	NOUN
amwa-432	207	5	.	.	PUNCT
amwa-432	208	1	2012;11(9):675	2012;11(9):675	NUM
amwa-432	208	2	-	-	SYM
amwa-432	208	3	691	691	NUM
amwa-432	208	4	.	.	PUNCT
amwa-432	209	1	25	25	NUM
amwa-432	209	2	.	.	PUNCT
amwa-432	209	3	bramante	bramante	PROPN
amwa-432	209	4	ct	ct	PROPN
amwa-432	209	5	,	,	PUNCT
amwa-432	209	6	raatz	raatz	VERB
amwa-432	209	7	s	s	PROPN
amwa-432	209	8	,	,	PUNCT
amwa-432	209	9	bomberg	bomberg	PROPN
amwa-432	209	10	em	em	PRON
amwa-432	209	11	,	,	PUNCT
amwa-432	209	12	oberle	oberle	PROPN
amwa-432	209	13	mm	mm	PROPN
amwa-432	209	14	,	,	PUNCT
amwa-432	209	15	ryder	ryder	PROPN
amwa-432	209	16	jr	jr	PROPN
amwa-432	209	17	.	.	PUNCT
amwa-432	210	1	cardiovascular	cardiovascular	ADJ
amwa-432	210	2	risks	risk	NOUN
amwa-432	210	3	and	and	CCONJ
amwa-432	210	4	benefits	benefit	NOUN
amwa-432	210	5	of	of	ADP
amwa-432	210	6	medications	medication	NOUN
amwa-432	210	7	used	use	VERB
amwa-432	210	8	for	for	ADP
amwa-432	210	9	weight	weight	NOUN
amwa-432	210	10	loss	loss	NOUN
amwa-432	210	11	.	.	PUNCT
amwa-432	211	1	front	front	ADJ
amwa-432	211	2	endocrinol	endocrinol	NOUN
amwa-432	211	3	(	(	PUNCT
amwa-432	211	4	lausanne	lausanne	PROPN
amwa-432	211	5	)	)	PUNCT
amwa-432	211	6	.	.	PUNCT
amwa-432	212	1	2019;10:883	2019;10:883	NUM
amwa-432	212	2	26	26	NUM
amwa-432	212	3	.	.	PUNCT
amwa-432	213	1	lingvay	lingvay	PROPN
amwa-432	213	2	i	i	PRON
amwa-432	213	3	,	,	PUNCT
amwa-432	213	4	mosenzon	mosenzon	PROPN
amwa-432	213	5	o	o	NOUN
amwa-432	213	6	,	,	PUNCT
amwa-432	213	7	brown	brown	PROPN
amwa-432	213	8	k	k	PROPN
amwa-432	213	9	,	,	PUNCT
amwa-432	213	10	et	et	PROPN
amwa-432	213	11	al	al	PROPN
amwa-432	213	12	.	.	PROPN
amwa-432	213	13	systolic	systolic	ADJ
amwa-432	213	14	blood	blood	NOUN
amwa-432	213	15	pressure	pressure	NOUN
amwa-432	213	16	reduction	reduction	NOUN
amwa-432	213	17	with	with	ADP
amwa-432	213	18	tirzepatide	tirzepatide	NOUN
amwa-432	213	19	in	in	ADP
amwa-432	213	20	patients	patient	NOUN
amwa-432	213	21	with	with	ADP
amwa-432	213	22	type	type	NOUN
amwa-432	213	23	2	2	NUM
amwa-432	213	24	diabetes	diabete	NOUN
amwa-432	213	25	:	:	PUNCT
amwa-432	213	26	insights	insight	NOUN
amwa-432	213	27	from	from	ADP
amwa-432	213	28	surpass	surpass	ADJ
amwa-432	213	29	clinical	clinical	ADJ
amwa-432	213	30	program	program	NOUN
amwa-432	213	31	.	.	PUNCT
amwa-432	214	1	cardiovasc	cardiovasc	PROPN
amwa-432	214	2	diabetol	diabetol	VERB
amwa-432	214	3	.	.	PUNCT
amwa-432	215	1	2023;22(1):66	2023;22(1):66	NUM
amwa-432	215	2	.	.	PUNCT
amwa-432	216	1	27	27	NUM
amwa-432	216	2	.	.	PUNCT
amwa-432	217	1	jiao	jiao	PROPN
amwa-432	217	2	f	f	PROPN
amwa-432	217	3	,	,	PUNCT
amwa-432	217	4	hu	hu	PROPN
amwa-432	217	5	x	x	PROPN
amwa-432	217	6	,	,	PUNCT
amwa-432	217	7	yin	yin	PROPN
amwa-432	217	8	h	h	PROPN
amwa-432	217	9	,	,	PUNCT
amwa-432	217	10	et	et	PROPN
amwa-432	217	11	al	al	PROPN
amwa-432	217	12	.	.	PROPN
amwa-432	217	13	inhibition	inhibition	NOUN
amwa-432	217	14	of	of	ADP
amwa-432	217	15	c	c	NOUN
amwa-432	217	16	-	-	PUNCT
amwa-432	217	17	jun	jun	PROPN
amwa-432	217	18	in	in	ADP
amwa-432	217	19	agrp	agrp	NOUN
amwa-432	217	20	neurons	neuron	NOUN
amwa-432	217	21	increases	increase	VERB
amwa-432	217	22	stress	stress	NOUN
amwa-432	217	23	-	-	PUNCT
amwa-432	217	24	induced	induce	VERB
amwa-432	217	25	anxiety	anxiety	NOUN
amwa-432	217	26	and	and	CCONJ
amwa-432	217	27	colitis	colitis	NOUN
amwa-432	217	28	susceptibility	susceptibility	NOUN
amwa-432	217	29	.	.	PUNCT
amwa-432	218	1	commun	commun	PROPN
amwa-432	218	2	biol	biol	PROPN
amwa-432	218	3	.	.	PUNCT
amwa-432	219	1	2023;6(1):50	2023;6(1):50	NUM
amwa-432	219	2	.	.	NOUN
amwa-432	219	3	28	28	NUM
amwa-432	219	4	.	.	PUNCT
amwa-432	220	1	skelley	skelley	PROPN
amwa-432	220	2	jw	jw	PROPN
amwa-432	220	3	,	,	PUNCT
amwa-432	220	4	swearengin	swearengin	PROPN
amwa-432	220	5	k	k	PROPN
amwa-432	220	6	,	,	PUNCT
amwa-432	220	7	york	york	PROPN
amwa-432	220	8	al	al	PROPN
amwa-432	220	9	,	,	PUNCT
amwa-432	220	10	glover	glover	PROPN
amwa-432	220	11	lh	lh	PROPN
amwa-432	220	12	.	.	PUNCT
amwa-432	221	1	the	the	DET
amwa-432	221	2	impact	impact	NOUN
amwa-432	221	3	of	of	ADP
amwa-432	221	4	tirzepatide	tirzepatide	NOUN
amwa-432	221	5	and	and	CCONJ
amwa-432	221	6	glucagon	glucagon	NOUN
amwa-432	221	7	-	-	PUNCT
amwa-432	221	8	like	like	ADJ
amwa-432	221	9	peptide	peptide	NOUN
amwa-432	221	10	1	1	NUM
amwa-432	221	11	receptor	receptor	NOUN
amwa-432	221	12	agonists	agonist	NOUN
amwa-432	221	13	on	on	ADP
amwa-432	221	14	oral	oral	ADJ
amwa-432	221	15	hormonal	hormonal	ADJ
amwa-432	221	16	contraception	contraception	NOUN
amwa-432	221	17	.	.	PUNCT
amwa-432	222	1	j	j	PROPN
amwa-432	222	2	am	be	AUX
amwa-432	222	3	pharm	pharm	PROPN
amwa-432	222	4	assoc	assoc	PROPN
amwa-432	222	5	(	(	PUNCT
amwa-432	222	6	2003	2003	NUM
amwa-432	222	7	)	)	PUNCT
amwa-432	222	8	.	.	PUNCT
amwa-432	223	1	2024;64(1):204	2024;64(1):204	NUM
amwa-432	223	2	-	-	PUNCT
amwa-432	223	3	211.e4	211.e4	NUM
amwa-432	223	4	.	.	PUNCT
amwa-432	224	1	29	29	NUM
amwa-432	224	2	.	.	PUNCT
amwa-432	225	1	singh	singh	PROPN
amwa-432	225	2	s	s	PROPN
amwa-432	225	3	,	,	PUNCT
amwa-432	225	4	chandan	chandan	PROPN
amwa-432	225	5	s	s	PROPN
amwa-432	225	6	,	,	PUNCT
amwa-432	225	7	dahiya	dahiya	NOUN
amwa-432	225	8	ds	ds	PROPN
amwa-432	225	9	,	,	PUNCT
amwa-432	225	10	et	et	PROPN
amwa-432	225	11	al	al	PROPN
amwa-432	225	12	.	.	PROPN
amwa-432	225	13	impact	impact	NOUN
amwa-432	225	14	of	of	ADP
amwa-432	225	15	glp-1	glp-1	NOUN
amwa-432	225	16	receptor	receptor	NOUN
amwa-432	225	17	agonists	agonist	NOUN
amwa-432	225	18	in	in	ADP
amwa-432	225	19	gastrointestinal	gastrointestinal	ADJ
amwa-432	225	20	endoscopy	endoscopy	NOUN
amwa-432	225	21	:	:	PUNCT
amwa-432	225	22	an	an	DET
amwa-432	225	23	updated	update	VERB
amwa-432	225	24	review	review	NOUN
amwa-432	225	25	.	.	PUNCT
amwa-432	226	1	j	j	PROPN
amwa-432	226	2	clin	clin	PROPN
amwa-432	226	3	med	med	PROPN
amwa-432	226	4	.	.	PUNCT
amwa-432	227	1	2024;13(18	2024;13(18	NUM
amwa-432	227	2	)	)	PUNCT
amwa-432	227	3	.	.	PUNCT
amwa-432	228	1	http://www.amwajournal.org	http://www.amwajournal.org	PROPN
amwa-432	229	1	https://www.cdc.gov/obesity/adult-obesity-facts/index.html	https://www.cdc.gov/obesity/adult-obesity-facts/index.html	INTJ
amwa-432	229	2	https://www.cdc.gov/obesity/adult-obesity-facts/index.html	https://www.cdc.gov/obesity/adult-obesity-facts/index.html	PROPN
amwa-432	229	3	https://www.cdc.gov/obesity/childhood-obesity-facts/childhood-obesity-facts.html	https://www.cdc.gov/obesity/childhood-obesity-facts/childhood-obesity-facts.html	VERB
amwa-432	229	4	https://www.cdc.gov/obesity/childhood-obesity-facts/childhood-obesity-facts.html	https://www.cdc.gov/obesity/childhood-obesity-facts/childhood-obesity-facts.html	PUNCT