id	sid	tid	token	lemma	pos
bracis-19059	1	1	ensemble	ensemble	ADJ
bracis-19059	1	2	of	of	ADP
bracis-19059	1	3	protein	protein	NOUN
bracis-19059	1	4	stability	stability	NOUN
bracis-19059	1	5	upon	upon	SCONJ
bracis-19059	1	6	point	point	NOUN
bracis-19059	1	7	mutation	mutation	NOUN
bracis-19059	1	8	predictors	predictor	NOUN
bracis-19059	1	9	|	|	ADV
bracis-19059	1	10	springer	springer	NOUN
bracis-19059	1	11	nature	nature	NOUN
bracis-19059	1	12	link	link	PROPN
bracis-19059	1	13	(	(	PUNCT
bracis-19059	1	14	formerly	formerly	ADV
bracis-19059	1	15	springerlink	springerlink	NOUN
bracis-19059	1	16	)	)	PUNCT
bracis-19059	1	17	skip	skip	VERB
bracis-19059	1	18	to	to	ADP
bracis-19059	1	19	main	main	ADJ
bracis-19059	1	20	content	content	NOUN
bracis-19059	1	21	advertisement	advertisement	NOUN
bracis-19059	1	22	log	log	NOUN
bracis-19059	1	23	in	in	ADP
bracis-19059	1	24	menu	menu	NOUN
bracis-19059	1	25	find	find	VERB
bracis-19059	1	26	a	a	DET
bracis-19059	1	27	journal	journal	NOUN
bracis-19059	1	28	publish	publish	VERB
bracis-19059	1	29	with	with	ADP
bracis-19059	1	30	us	we	PRON
bracis-19059	1	31	track	track	VERB
bracis-19059	1	32	your	your	PRON
bracis-19059	1	33	research	research	NOUN
bracis-19059	1	34	search	search	NOUN
bracis-19059	1	35	cart	cart	NOUN
bracis-19059	1	36	home	home	NOUN
bracis-19059	1	37	intelligent	intelligent	ADJ
bracis-19059	1	38	systems	system	NOUN
bracis-19059	1	39	conference	conference	NOUN
bracis-19059	1	40	paper	paper	NOUN
bracis-19059	1	41	ensemble	ensemble	ADJ
bracis-19059	1	42	of	of	ADP
bracis-19059	1	43	protein	protein	NOUN
bracis-19059	1	44	stability	stability	NOUN
bracis-19059	1	45	upon	upon	SCONJ
bracis-19059	1	46	point	point	NOUN
bracis-19059	1	47	mutation	mutation	NOUN
bracis-19059	1	48	predictors	predictor	NOUN
bracis-19059	1	49	conference	conference	NOUN
bracis-19059	1	50	paper	paper	NOUN
bracis-19059	1	51	first	first	ADV
bracis-19059	1	52	online	online	ADV
bracis-19059	1	53	:	:	PUNCT
bracis-19059	1	54	28	28	NUM
bracis-19059	1	55	november	november	PROPN
bracis-19059	1	56	2021	2021	NUM
bracis-19059	2	1	pp	pp	ADP
bracis-19059	2	2	73–88	73–88	NUM
bracis-19059	2	3	cite	cite	VERB
bracis-19059	2	4	this	this	DET
bracis-19059	2	5	conference	conference	NOUN
bracis-19059	2	6	paper	paper	NOUN
bracis-19059	2	7	access	access	NOUN
bracis-19059	2	8	provided	provide	VERB
bracis-19059	2	9	by	by	ADP
bracis-19059	2	10	university	university	PROPN
bracis-19059	2	11	of	of	ADP
bracis-19059	2	12	notre	notre	PROPN
bracis-19059	2	13	dame	dame	PROPN
bracis-19059	2	14	hesburgh	hesburgh	PROPN
bracis-19059	2	15	library	library	PROPN
bracis-19059	2	16	download	download	PROPN
bracis-19059	2	17	book	book	NOUN
bracis-19059	2	18	pdf	pdf	PROPN
bracis-19059	2	19	download	download	NOUN
bracis-19059	2	20	book	book	NOUN
bracis-19059	2	21	epub	epub	PROPN
bracis-19059	2	22	intelligent	intelligent	ADJ
bracis-19059	2	23	systems	system	NOUN
bracis-19059	2	24	(	(	PUNCT
bracis-19059	2	25	bracis	bracis	NOUN
bracis-19059	2	26	2021	2021	NUM
bracis-19059	2	27	)	)	PUNCT
bracis-19059	2	28	ensemble	ensemble	ADJ
bracis-19059	2	29	of	of	ADP
bracis-19059	2	30	protein	protein	NOUN
bracis-19059	2	31	stability	stability	NOUN
bracis-19059	2	32	upon	upon	SCONJ
bracis-19059	2	33	point	point	NOUN
bracis-19059	2	34	mutation	mutation	NOUN
bracis-19059	2	35	predictors	predictor	NOUN
bracis-19059	2	36	download	download	VERB
bracis-19059	2	37	book	book	NOUN
bracis-19059	2	38	pdf	pdf	PROPN
bracis-19059	2	39	download	download	NOUN
bracis-19059	2	40	book	book	PROPN
bracis-19059	2	41	epub	epub	PROPN
bracis-19059	2	42	eduardo	eduardo	PROPN
bracis-19059	2	43	kenji	kenji	PROPN
bracis-19059	2	44	hasegawa	hasegawa	PROPN
bracis-19059	2	45	de	de	PROPN
bracis-19059	2	46	freitas	freitas	PROPN
bracis-19059	2	47	  	  	SPACE
bracis-19059	2	48	orcid	orcid	NOUN
bracis-19059	2	49	:	:	PUNCT
bracis-19059	2	50	orcid.org/0000-0002-1476-477910	orcid.org/0000-0002-1476-477910	NOUN
bracis-19059	2	51	,	,	PUNCT
bracis-19059	2	52	alex	alex	PROPN
bracis-19059	2	53	dias	dias	PROPN
bracis-19059	2	54	camargo	camargo	PROPN
bracis-19059	2	55	  	  	SPACE
bracis-19059	2	56	orcid	orcid	PROPN
bracis-19059	2	57	:	:	PUNCT
bracis-19059	3	1	orcid.org/0000-0002-6377-937910	orcid.org/0000-0002-6377-937910	NOUN
bracis-19059	3	2	,	,	PUNCT
bracis-19059	3	3	maurício	maurício	NOUN
bracis-19059	3	4	balboni	balboni	NOUN
bracis-19059	3	5	  	  	SPACE
bracis-19059	3	6	orcid	orcid	NOUN
bracis-19059	3	7	:	:	PUNCT
bracis-19059	3	8	orcid.org/0000-0001-7653-096210	orcid.org/0000-0001-7653-096210	PROPN
bracis-19059	3	9	,	,	PUNCT
bracis-19059	3	10	adriano	adriano	PROPN
bracis-19059	3	11	v.	v.	ADP
bracis-19059	3	12	werhli	werhli	PROPN
bracis-19059	3	13	  	  	SPACE
bracis-19059	3	14	orcid	orcid	NOUN
bracis-19059	3	15	:	:	PUNCT
bracis-19059	3	16	orcid.org/0000-0001-7107-502410	orcid.org/0000-0001-7107-502410	PROPN
bracis-19059	3	17	&	&	CCONJ
bracis-19059	3	18	…	…	PUNCT
bracis-19059	3	19	karina	karina	PROPN
bracis-19059	3	20	dos	dos	PROPN
bracis-19059	3	21	santos	santos	PROPN
bracis-19059	3	22	machado	machado	PROPN
bracis-19059	3	23	  	  	SPACE
bracis-19059	3	24	orcid	orcid	PROPN
bracis-19059	3	25	:	:	PUNCT
bracis-19059	3	26	orcid.org/0000-0002-8966-570810	orcid.org/0000-0002-8966-570810	NOUN
bracis-19059	3	27	  	  	SPACE
bracis-19059	3	28	show	show	VERB
bracis-19059	3	29	authors	author	NOUN
bracis-19059	3	30	part	part	NOUN
bracis-19059	3	31	of	of	ADP
bracis-19059	3	32	the	the	DET
bracis-19059	3	33	book	book	NOUN
bracis-19059	3	34	series	series	NOUN
bracis-19059	3	35	:	:	PUNCT
bracis-19059	3	36	lecture	lecture	NOUN
bracis-19059	3	37	notes	note	NOUN
bracis-19059	3	38	in	in	ADP
bracis-19059	3	39	computer	computer	NOUN
bracis-19059	3	40	science	science	NOUN
bracis-19059	3	41	(	(	PUNCT
bracis-19059	3	42	(	(	PUNCT
bracis-19059	3	43	lnai	lnai	ADJ
bracis-19059	3	44	,	,	PUNCT
bracis-19059	3	45	volume	volume	NOUN
bracis-19059	3	46	13074	13074	NUM
bracis-19059	3	47	)	)	PUNCT
bracis-19059	3	48	)	)	PUNCT
bracis-19059	3	49	included	include	VERB
bracis-19059	3	50	in	in	ADP
bracis-19059	3	51	the	the	DET
bracis-19059	3	52	following	follow	VERB
bracis-19059	3	53	conference	conference	NOUN
bracis-19059	3	54	series	series	NOUN
bracis-19059	3	55	:	:	PUNCT
bracis-19059	3	56	brazilian	brazilian	ADJ
bracis-19059	3	57	conference	conference	NOUN
bracis-19059	3	58	on	on	ADP
bracis-19059	3	59	intelligent	intelligent	ADJ
bracis-19059	3	60	systems	system	NOUN
bracis-19059	3	61	1240	1240	NUM
bracis-19059	3	62	accesses	access	VERB
bracis-19059	3	63	abstract	abstract	ADJ
bracis-19059	3	64	computational	computational	ADJ
bracis-19059	3	65	determination	determination	NOUN
bracis-19059	3	66	of	of	ADP
bracis-19059	3	67	protein	protein	NOUN
bracis-19059	3	68	stability	stability	NOUN
bracis-19059	3	69	upon	upon	SCONJ
bracis-19059	3	70	point	point	NOUN
bracis-19059	3	71	mutations	mutation	NOUN
bracis-19059	3	72	is	be	AUX
bracis-19059	3	73	very	very	ADV
bracis-19059	3	74	useful	useful	ADJ
bracis-19059	3	75	in	in	ADP
bracis-19059	3	76	a	a	DET
bracis-19059	3	77	wide	wide	ADJ
bracis-19059	3	78	field	field	NOUN
bracis-19059	3	79	of	of	ADP
bracis-19059	3	80	applications	application	NOUN
bracis-19059	3	81	.	.	PUNCT
bracis-19059	4	1	the	the	DET
bracis-19059	4	2	reliability	reliability	NOUN
bracis-19059	4	3	of	of	ADP
bracis-19059	4	4	such	such	ADJ
bracis-19059	4	5	computational	computational	ADJ
bracis-19059	4	6	predictions	prediction	NOUN
bracis-19059	4	7	is	be	AUX
bracis-19059	4	8	essential	essential	ADJ
bracis-19059	4	9	.	.	PUNCT
bracis-19059	5	1	unfortunately	unfortunately	ADV
bracis-19059	5	2	,	,	PUNCT
bracis-19059	5	3	existing	exist	VERB
bracis-19059	5	4	computational	computational	ADJ
bracis-19059	5	5	tools	tool	NOUN
bracis-19059	5	6	frequently	frequently	ADV
bracis-19059	5	7	disagree	disagree	VERB
bracis-19059	5	8	in	in	ADP
bracis-19059	5	9	their	their	PRON
bracis-19059	5	10	results	result	NOUN
bracis-19059	5	11	.	.	PUNCT
bracis-19059	6	1	in	in	ADP
bracis-19059	6	2	the	the	DET
bracis-19059	6	3	present	present	ADJ
bracis-19059	6	4	study	study	NOUN
bracis-19059	6	5	,	,	PUNCT
bracis-19059	6	6	the	the	DET
bracis-19059	6	7	usage	usage	NOUN
bracis-19059	6	8	of	of	ADP
bracis-19059	6	9	ensemble	ensemble	ADJ
bracis-19059	6	10	learning	learning	NOUN
bracis-19059	6	11	algorithms	algorithm	NOUN
bracis-19059	6	12	to	to	PART
bracis-19059	6	13	aggregate	aggregate	VERB
bracis-19059	6	14	the	the	DET
bracis-19059	6	15	results	result	NOUN
bracis-19059	6	16	from	from	ADP
bracis-19059	6	17	different	different	ADJ
bracis-19059	6	18	stability	stability	NOUN
bracis-19059	6	19	prediction	prediction	NOUN
bracis-19059	6	20	tools	tool	NOUN
bracis-19059	6	21	is	be	AUX
bracis-19059	6	22	investigated	investigate	VERB
bracis-19059	6	23	.	.	PUNCT
bracis-19059	7	1	techniques	technique	NOUN
bracis-19059	7	2	of	of	ADP
bracis-19059	7	3	stacking	stacking	NOUN
bracis-19059	7	4	,	,	PUNCT
bracis-19059	7	5	bagging	bagging	NOUN
bracis-19059	7	6	,	,	PUNCT
bracis-19059	7	7	and	and	CCONJ
bracis-19059	7	8	boosting	boost	VERB
bracis-19059	7	9	as	as	ADV
bracis-19059	7	10	well	well	ADV
bracis-19059	7	11	as	as	ADP
bracis-19059	7	12	different	different	ADJ
bracis-19059	7	13	machine	machine	NOUN
bracis-19059	7	14	learning	learn	VERB
bracis-19059	7	15	algorithms	algorithm	NOUN
bracis-19059	7	16	as	as	SCONJ
bracis-19059	7	17	combiner	combiner	NOUN
bracis-19059	7	18	function	function	NOUN
bracis-19059	7	19	are	be	AUX
bracis-19059	7	20	explored	explore	VERB
bracis-19059	7	21	.	.	PUNCT
bracis-19059	8	1	all	all	DET
bracis-19059	8	2	the	the	DET
bracis-19059	8	3	investigation	investigation	NOUN
bracis-19059	8	4	is	be	AUX
bracis-19059	8	5	carried	carry	VERB
bracis-19059	8	6	out	out	ADP
bracis-19059	8	7	in	in	ADP
bracis-19059	8	8	real	real	ADJ
bracis-19059	8	9	dataset	dataset	NOUN
bracis-19059	8	10	protherm	protherm	NOUN
bracis-19059	8	11	for	for	ADP
bracis-19059	8	12	which	which	PRON
bracis-19059	8	13	experimental	experimental	ADJ
bracis-19059	8	14	results	result	NOUN
bracis-19059	8	15	are	be	AUX
bracis-19059	8	16	known	know	VERB
bracis-19059	8	17	.	.	PUNCT
bracis-19059	9	1	the	the	DET
bracis-19059	9	2	proposed	propose	VERB
bracis-19059	9	3	methodology	methodology	NOUN
bracis-19059	9	4	was	be	AUX
bracis-19059	9	5	validated	validate	VERB
bracis-19059	9	6	considering	consider	VERB
bracis-19059	9	7	two	two	NUM
bracis-19059	9	8	different	different	ADJ
bracis-19059	9	9	experiments	experiment	NOUN
bracis-19059	9	10	according	accord	VERB
bracis-19059	9	11	to	to	ADP
bracis-19059	9	12	the	the	DET
bracis-19059	9	13	training	training	NOUN
bracis-19059	9	14	set	set	NOUN
bracis-19059	9	15	.	.	PUNCT
bracis-19059	10	1	results	result	NOUN
bracis-19059	10	2	show	show	VERB
bracis-19059	10	3	that	that	SCONJ
bracis-19059	10	4	our	our	PRON
bracis-19059	10	5	proposed	propose	VERB
bracis-19059	10	6	ensemble	ensemble	ADJ
bracis-19059	10	7	approach	approach	NOUN
bracis-19059	10	8	is	be	AUX
bracis-19059	10	9	appropriate	appropriate	ADJ
bracis-19059	10	10	to	to	PART
bracis-19059	10	11	predict	predict	VERB
bracis-19059	10	12	the	the	DET
bracis-19059	10	13	effect	effect	NOUN
bracis-19059	10	14	of	of	ADP
bracis-19059	10	15	point	point	NOUN
bracis-19059	10	16	mutations	mutation	NOUN
bracis-19059	10	17	on	on	ADP
bracis-19059	10	18	protein	protein	NOUN
bracis-19059	10	19	stability	stability	NOUN
bracis-19059	10	20	showing	show	VERB
bracis-19059	10	21	more	more	ADV
bracis-19059	10	22	reliable	reliable	ADJ
bracis-19059	10	23	results	result	NOUN
bracis-19059	10	24	than	than	ADP
bracis-19059	10	25	the	the	DET
bracis-19059	10	26	individual	individual	ADJ
bracis-19059	10	27	tools	tool	NOUN
bracis-19059	10	28	improving	improve	VERB
bracis-19059	10	29	overall	overall	ADJ
bracis-19059	10	30	accuracy	accuracy	NOUN
bracis-19059	10	31	,	,	PUNCT
bracis-19059	10	32	precision	precision	NOUN
bracis-19059	10	33	,	,	PUNCT
bracis-19059	10	34	and/or	and/or	CCONJ
bracis-19059	10	35	recall	recall	NOUN
bracis-19059	10	36	.	.	PUNCT
bracis-19059	11	1	this	this	DET
bracis-19059	11	2	study	study	NOUN
bracis-19059	11	3	was	be	AUX
bracis-19059	11	4	supported	support	VERB
bracis-19059	11	5	by	by	ADP
bracis-19059	11	6	capes	cape	NOUN
bracis-19059	11	7	edital	edital	ADJ
bracis-19059	11	8	biologia	biologia	PROPN
bracis-19059	11	9	computacional	computacional	NOUN
bracis-19059	11	10	(	(	PUNCT
bracis-19059	11	11	51/2013	51/2013	NUM
bracis-19059	11	12	)	)	PUNCT
bracis-19059	11	13	,	,	PUNCT
bracis-19059	11	14	capes	cape	NOUN
bracis-19059	11	15	financial	financial	PROPN
bracis-19059	11	16	code	code	PROPN
bracis-19059	11	17	001	001	NUM
bracis-19059	11	18	and	and	CCONJ
bracis-19059	11	19	cnpq	cnpq	NOUN
bracis-19059	11	20	(	(	PUNCT
bracis-19059	11	21	439582/2018	439582/2018	NUM
bracis-19059	11	22	-	-	SYM
bracis-19059	11	23	0	0	NUM
bracis-19059	11	24	)	)	PUNCT
bracis-19059	11	25	.	.	PUNCT
bracis-19059	12	1	access	access	NOUN
bracis-19059	12	2	provided	provide	VERB
bracis-19059	12	3	by	by	ADP
bracis-19059	12	4	university	university	PROPN
bracis-19059	12	5	of	of	ADP
bracis-19059	12	6	notre	notre	PROPN
bracis-19059	12	7	dame	dame	PROPN
bracis-19059	12	8	hesburgh	hesburgh	PROPN
bracis-19059	12	9	library	library	PROPN
bracis-19059	12	10	.	.	PUNCT
bracis-19059	13	1	download	download	PROPN
bracis-19059	13	2	conference	conference	NOUN
bracis-19059	13	3	paper	paper	NOUN
bracis-19059	13	4	pdf	pdf	NOUN
bracis-19059	13	5	similar	similar	ADJ
bracis-19059	13	6	content	content	NOUN
bracis-19059	13	7	being	be	AUX
bracis-19059	13	8	viewed	view	VERB
bracis-19059	13	9	by	by	ADP
bracis-19059	13	10	others	other	NOUN
bracis-19059	13	11	computational	computational	ADJ
bracis-19059	13	12	approaches	approach	NOUN
bracis-19059	13	13	for	for	ADP
bracis-19059	13	14	predicting	predict	VERB
bracis-19059	13	15	mutant	mutant	ADJ
bracis-19059	13	16	protein	protein	NOUN
bracis-19059	13	17	stability	stability	NOUN
bracis-19059	13	18	article	article	NOUN
bracis-19059	13	19	09	09	NUM
bracis-19059	13	20	may	may	PROPN
bracis-19059	13	21	2016	2016	NUM
bracis-19059	13	22	a	a	DET
bracis-19059	13	23	way	way	NOUN
bracis-19059	13	24	forward	forward	ADV
bracis-19059	13	25	for	for	ADP
bracis-19059	13	26	predictors	predictor	NOUN
bracis-19059	13	27	of	of	ADP
bracis-19059	13	28	protein	protein	NOUN
bracis-19059	13	29	thermodynamics	thermodynamic	NOUN
bracis-19059	13	30	stability	stability	NOUN
bracis-19059	13	31	changes	change	VERB
bracis-19059	13	32	due	due	ADJ
bracis-19059	13	33	to	to	ADP
bracis-19059	13	34	mutations	mutation	NOUN
bracis-19059	13	35	in	in	ADP
bracis-19059	13	36	the	the	DET
bracis-19059	13	37	unavailability	unavailability	NOUN
bracis-19059	13	38	of	of	ADP
bracis-19059	13	39	experimental	experimental	ADJ
bracis-19059	13	40	protein	protein	NOUN
bracis-19059	13	41	structures	structure	NOUN
bracis-19059	13	42	chapter	chapter	NOUN
bracis-19059	13	43	©	©	PROPN
bracis-19059	13	44	2024	2024	NUM
bracis-19059	13	45	proteus	proteus	NOUN
bracis-19059	13	46	:	:	PUNCT
bracis-19059	13	47	an	an	DET
bracis-19059	13	48	algorithm	algorithm	NOUN
bracis-19059	13	49	for	for	ADP
bracis-19059	13	50	proposing	propose	VERB
bracis-19059	13	51	stabilizing	stabilizing	NOUN
bracis-19059	13	52	mutation	mutation	NOUN
bracis-19059	13	53	pairs	pair	NOUN
bracis-19059	13	54	based	base	VERB
bracis-19059	13	55	on	on	ADP
bracis-19059	13	56	interactions	interaction	NOUN
bracis-19059	13	57	observed	observe	VERB
bracis-19059	13	58	in	in	ADP
bracis-19059	13	59	known	know	VERB
bracis-19059	13	60	protein	protein	NOUN
bracis-19059	13	61	3d	3d	NUM
bracis-19059	13	62	structures	structure	NOUN
bracis-19059	13	63	article	article	NOUN
bracis-19059	13	64	open	open	ADJ
bracis-19059	13	65	access	access	NOUN
bracis-19059	13	66	01	01	NUM
bracis-19059	13	67	july	july	PROPN
bracis-19059	13	68	2020	2020	NUM
bracis-19059	13	69	explore	explore	VERB
bracis-19059	13	70	related	related	ADJ
bracis-19059	13	71	subjects	subject	NOUN
bracis-19059	13	72	discover	discover	VERB
bracis-19059	13	73	the	the	DET
bracis-19059	13	74	latest	late	ADJ
bracis-19059	13	75	articles	article	NOUN
bracis-19059	13	76	,	,	PUNCT
bracis-19059	13	77	books	book	NOUN
bracis-19059	13	78	and	and	CCONJ
bracis-19059	13	79	news	news	NOUN
bracis-19059	13	80	in	in	ADP
bracis-19059	13	81	related	related	ADJ
bracis-19059	13	82	subjects	subject	NOUN
bracis-19059	13	83	,	,	PUNCT
bracis-19059	13	84	suggested	suggest	VERB
bracis-19059	13	85	using	use	VERB
bracis-19059	13	86	machine	machine	NOUN
bracis-19059	13	87	learning	learning	NOUN
bracis-19059	13	88	.	.	PUNCT
bracis-19059	14	1	learning	learn	VERB
bracis-19059	14	2	algorithms	algorithm	NOUN
bracis-19059	14	3	protein	protein	NOUN
bracis-19059	14	4	structure	structure	NOUN
bracis-19059	14	5	predictions	prediction	NOUN
bracis-19059	14	6	protein	protein	NOUN
bracis-19059	14	7	folding	fold	VERB
bracis-19059	14	8	protein	protein	NOUN
bracis-19059	14	9	function	function	NOUN
bracis-19059	14	10	predictions	prediction	NOUN
bracis-19059	14	11	structure	structure	NOUN
bracis-19059	14	12	prediction	prediction	NOUN
bracis-19059	14	13	bioinformatics	bioinformatics	NOUN
bracis-19059	14	14	1	1	NUM
bracis-19059	14	15	introduction	introduction	NOUN
bracis-19059	14	16	the	the	DET
bracis-19059	14	17	latest	late	ADJ
bracis-19059	14	18	research	research	NOUN
bracis-19059	14	19	and	and	CCONJ
bracis-19059	14	20	development	development	NOUN
bracis-19059	14	21	in	in	ADP
bracis-19059	14	22	biological	biological	ADJ
bracis-19059	14	23	experiments	experiment	NOUN
bracis-19059	14	24	and	and	CCONJ
bracis-19059	14	25	techniques	technique	NOUN
bracis-19059	14	26	have	have	AUX
bracis-19059	14	27	created	create	VERB
bracis-19059	14	28	a	a	DET
bracis-19059	14	29	deluge	deluge	NOUN
bracis-19059	14	30	of	of	ADP
bracis-19059	14	31	experimental	experimental	ADJ
bracis-19059	14	32	data	datum	NOUN
bracis-19059	14	33	.	.	PUNCT
bracis-19059	15	1	to	to	PART
bracis-19059	15	2	deal	deal	VERB
bracis-19059	15	3	with	with	ADP
bracis-19059	15	4	this	this	DET
bracis-19059	15	5	quantity	quantity	NOUN
bracis-19059	15	6	and	and	CCONJ
bracis-19059	15	7	variety	variety	NOUN
bracis-19059	15	8	of	of	ADP
bracis-19059	15	9	data	datum	NOUN
bracis-19059	15	10	the	the	DET
bracis-19059	15	11	necessity	necessity	NOUN
bracis-19059	15	12	of	of	ADP
bracis-19059	15	13	computational	computational	ADJ
bracis-19059	15	14	methods	method	NOUN
bracis-19059	15	15	and	and	CCONJ
bracis-19059	15	16	tools	tool	NOUN
bracis-19059	15	17	is	be	AUX
bracis-19059	15	18	obvious	obvious	ADJ
bracis-19059	15	19	.	.	PUNCT
bracis-19059	16	1	in	in	ADP
bracis-19059	16	2	some	some	DET
bracis-19059	16	3	cases	case	NOUN
bracis-19059	16	4	,	,	PUNCT
bracis-19059	16	5	the	the	DET
bracis-19059	16	6	use	use	NOUN
bracis-19059	16	7	of	of	ADP
bracis-19059	16	8	data	datum	NOUN
bracis-19059	16	9	science	science	NOUN
bracis-19059	16	10	methodology	methodology	NOUN
bracis-19059	16	11	is	be	AUX
bracis-19059	16	12	mandatory	mandatory	ADJ
bracis-19059	16	13	.	.	PUNCT
bracis-19059	17	1	in	in	ADP
bracis-19059	17	2	all	all	DET
bracis-19059	17	3	living	live	VERB
bracis-19059	17	4	species	specie	NOUN
bracis-19059	17	5	,	,	PUNCT
bracis-19059	17	6	biological	biological	ADJ
bracis-19059	17	7	information	information	NOUN
bracis-19059	17	8	is	be	AUX
bracis-19059	17	9	stored	store	VERB
bracis-19059	17	10	in	in	ADP
bracis-19059	17	11	the	the	DET
bracis-19059	17	12	dna	dna	PROPN
bracis-19059	17	13	(	(	PUNCT
bracis-19059	17	14	deoxyribonucleic	deoxyribonucleic	ADJ
bracis-19059	17	15	acid	acid	NOUN
bracis-19059	17	16	)	)	PUNCT
bracis-19059	17	17	.	.	PUNCT
bracis-19059	18	1	dna	dna	PROPN
bracis-19059	18	2	can	can	AUX
bracis-19059	18	3	be	be	AUX
bracis-19059	18	4	seen	see	VERB
bracis-19059	18	5	as	as	ADP
bracis-19059	18	6	the	the	DET
bracis-19059	18	7	source	source	NOUN
bracis-19059	18	8	code	code	NOUN
bracis-19059	18	9	that	that	PRON
bracis-19059	18	10	contains	contain	VERB
bracis-19059	18	11	all	all	DET
bracis-19059	18	12	the	the	DET
bracis-19059	18	13	instructions	instruction	NOUN
bracis-19059	18	14	to	to	PART
bracis-19059	18	15	create	create	VERB
bracis-19059	18	16	and	and	CCONJ
bracis-19059	18	17	sustain	sustain	VERB
bracis-19059	18	18	life	life	NOUN
bracis-19059	18	19	.	.	PUNCT
bracis-19059	19	1	to	to	PART
bracis-19059	19	2	transform	transform	VERB
bracis-19059	19	3	the	the	DET
bracis-19059	19	4	information	information	NOUN
bracis-19059	19	5	contained	contain	VERB
bracis-19059	19	6	in	in	ADP
bracis-19059	19	7	the	the	DET
bracis-19059	19	8	dna	dna	NOUN
bracis-19059	19	9	into	into	ADP
bracis-19059	19	10	functioning	function	VERB
bracis-19059	19	11	parts	part	NOUN
bracis-19059	19	12	,	,	PUNCT
bracis-19059	19	13	dna	dna	PROPN
bracis-19059	19	14	is	be	AUX
bracis-19059	19	15	transcript	transcript	NOUN
bracis-19059	19	16	as	as	ADP
bracis-19059	19	17	rna	rna	NOUN
bracis-19059	19	18	(	(	PUNCT
bracis-19059	19	19	ribonucleic	ribonucleic	ADJ
bracis-19059	19	20	acid	acid	NOUN
bracis-19059	19	21	)	)	PUNCT
bracis-19059	19	22	which	which	PRON
bracis-19059	19	23	is	be	AUX
bracis-19059	19	24	then	then	ADV
bracis-19059	19	25	translated	translate	VERB
bracis-19059	19	26	into	into	ADP
bracis-19059	19	27	proteins	protein	NOUN
bracis-19059	19	28	.	.	PUNCT
bracis-19059	20	1	proteins	protein	NOUN
bracis-19059	20	2	are	be	AUX
bracis-19059	20	3	the	the	DET
bracis-19059	20	4	principal	principal	ADJ
bracis-19059	20	5	biological	biological	ADJ
bracis-19059	20	6	elements	element	NOUN
bracis-19059	20	7	responsible	responsible	ADJ
bracis-19059	20	8	for	for	ADP
bracis-19059	20	9	executing	execute	VERB
bracis-19059	20	10	biological	biological	ADJ
bracis-19059	20	11	functions	function	NOUN
bracis-19059	20	12	.	.	PUNCT
bracis-19059	21	1	proteins	protein	NOUN
bracis-19059	21	2	can	can	AUX
bracis-19059	21	3	be	be	AUX
bracis-19059	21	4	thought	think	VERB
bracis-19059	21	5	of	of	ADP
bracis-19059	21	6	as	as	ADP
bracis-19059	21	7	the	the	DET
bracis-19059	21	8	compiled	compile	VERB
bracis-19059	21	9	result	result	NOUN
bracis-19059	21	10	of	of	ADP
bracis-19059	21	11	the	the	DET
bracis-19059	21	12	information	information	NOUN
bracis-19059	21	13	stored	store	VERB
bracis-19059	21	14	in	in	ADP
bracis-19059	21	15	the	the	DET
bracis-19059	21	16	dna	dna	NOUN
bracis-19059	21	17	[	[	X
bracis-19059	21	18	23	23	NUM
bracis-19059	21	19	]	]	PUNCT
bracis-19059	21	20	.	.	PUNCT
bracis-19059	22	1	moreover	moreover	ADV
bracis-19059	22	2	,	,	PUNCT
bracis-19059	22	3	proteins	protein	NOUN
bracis-19059	22	4	are	be	AUX
bracis-19059	22	5	the	the	DET
bracis-19059	22	6	most	most	ADV
bracis-19059	22	7	abundant	abundant	ADJ
bracis-19059	22	8	organic	organic	ADJ
bracis-19059	22	9	molecules	molecule	NOUN
bracis-19059	22	10	in	in	ADP
bracis-19059	22	11	living	living	NOUN
bracis-19059	22	12	systems	system	NOUN
bracis-19059	22	13	and	and	CCONJ
bracis-19059	22	14	have	have	VERB
bracis-19059	22	15	the	the	DET
bracis-19059	22	16	widest	wide	ADJ
bracis-19059	22	17	range	range	NOUN
bracis-19059	22	18	of	of	ADP
bracis-19059	22	19	functions	function	NOUN
bracis-19059	22	20	among	among	ADP
bracis-19059	22	21	macro	macro	NOUN
bracis-19059	22	22	-	-	NOUN
bracis-19059	22	23	molecules	molecule	NOUN
bracis-19059	22	24	.	.	PUNCT
bracis-19059	23	1	these	these	DET
bracis-19059	23	2	functions	function	NOUN
bracis-19059	23	3	can	can	AUX
bracis-19059	23	4	be	be	AUX
bracis-19059	23	5	structural	structural	ADJ
bracis-19059	23	6	,	,	PUNCT
bracis-19059	23	7	regulatory	regulatory	ADJ
bracis-19059	23	8	,	,	PUNCT
bracis-19059	23	9	contracting	contracting	NOUN
bracis-19059	23	10	,	,	PUNCT
bracis-19059	23	11	or	or	CCONJ
bracis-19059	23	12	protective	protective	ADJ
bracis-19059	23	13	.	.	PUNCT
bracis-19059	24	1	furthermore	furthermore	ADV
bracis-19059	24	2	,	,	PUNCT
bracis-19059	24	3	they	they	PRON
bracis-19059	24	4	can	can	AUX
bracis-19059	24	5	serve	serve	VERB
bracis-19059	24	6	as	as	ADP
bracis-19059	24	7	transport	transport	NOUN
bracis-19059	24	8	,	,	PUNCT
bracis-19059	24	9	storage	storage	NOUN
bracis-19059	24	10	,	,	PUNCT
bracis-19059	24	11	or	or	CCONJ
bracis-19059	24	12	membranes	membrane	NOUN
bracis-19059	24	13	,	,	PUNCT
bracis-19059	24	14	as	as	ADV
bracis-19059	24	15	well	well	ADV
bracis-19059	24	16	as	as	ADP
bracis-19059	24	17	being	be	AUX
bracis-19059	24	18	enzymes	enzyme	NOUN
bracis-19059	24	19	or	or	CCONJ
bracis-19059	24	20	toxins	toxin	NOUN
bracis-19059	24	21	.	.	PUNCT
bracis-19059	25	1	each	each	DET
bracis-19059	25	2	cell	cell	NOUN
bracis-19059	25	3	in	in	ADP
bracis-19059	25	4	a	a	DET
bracis-19059	25	5	living	live	VERB
bracis-19059	25	6	system	system	NOUN
bracis-19059	25	7	has	have	VERB
bracis-19059	25	8	thousands	thousand	NOUN
bracis-19059	25	9	of	of	ADP
bracis-19059	25	10	proteins	protein	NOUN
bracis-19059	25	11	where	where	SCONJ
bracis-19059	25	12	each	each	DET
bracis-19059	25	13	one	one	NOUN
bracis-19059	25	14	has	have	VERB
bracis-19059	25	15	a	a	DET
bracis-19059	25	16	function	function	NOUN
bracis-19059	25	17	,	,	PUNCT
bracis-19059	25	18	making	make	VERB
bracis-19059	25	19	their	their	PRON
bracis-19059	25	20	structures	structure	NOUN
bracis-19059	25	21	very	very	ADV
bracis-19059	25	22	varied	varied	ADJ
bracis-19059	25	23	.	.	PUNCT
bracis-19059	26	1	proteins	protein	NOUN
bracis-19059	26	2	are	be	AUX
bracis-19059	26	3	the	the	DET
bracis-19059	26	4	biological	biological	ADJ
bracis-19059	26	5	elements	element	NOUN
bracis-19059	26	6	that	that	PRON
bracis-19059	26	7	execute	execute	VERB
bracis-19059	26	8	functions	function	NOUN
bracis-19059	26	9	and	and	CCONJ
bracis-19059	26	10	frequently	frequently	ADV
bracis-19059	26	11	they	they	PRON
bracis-19059	26	12	are	be	AUX
bracis-19059	26	13	modified	modify	VERB
bracis-19059	26	14	(	(	PUNCT
bracis-19059	26	15	mutated	mutate	VERB
bracis-19059	26	16	)	)	PUNCT
bracis-19059	26	17	to	to	PART
bracis-19059	26	18	achieve	achieve	VERB
bracis-19059	26	19	specific	specific	ADJ
bracis-19059	26	20	goals	goal	NOUN
bracis-19059	26	21	.	.	PUNCT
bracis-19059	27	1	these	these	DET
bracis-19059	27	2	designed	design	VERB
bracis-19059	27	3	changes	change	NOUN
bracis-19059	27	4	,	,	PUNCT
bracis-19059	27	5	mutations	mutation	NOUN
bracis-19059	27	6	,	,	PUNCT
bracis-19059	27	7	are	be	AUX
bracis-19059	27	8	carried	carry	VERB
bracis-19059	27	9	out	out	ADP
bracis-19059	27	10	in	in	ADP
bracis-19059	27	11	specific	specific	ADJ
bracis-19059	27	12	parts	part	NOUN
bracis-19059	27	13	of	of	ADP
bracis-19059	27	14	the	the	DET
bracis-19059	27	15	dna	dna	NOUN
bracis-19059	27	16	using	use	VERB
bracis-19059	27	17	for	for	ADP
bracis-19059	27	18	example	example	NOUN
bracis-19059	27	19	site	site	NOUN
bracis-19059	27	20	-	-	PUNCT
bracis-19059	27	21	directed	direct	VERB
bracis-19059	27	22	mutagenesis	mutagenesis	NOUN
bracis-19059	27	23	.	.	PUNCT
bracis-19059	28	1	these	these	DET
bracis-19059	28	2	mutations	mutation	NOUN
bracis-19059	28	3	can	can	AUX
bracis-19059	28	4	produce	produce	VERB
bracis-19059	28	5	a	a	DET
bracis-19059	28	6	strong	strong	ADJ
bracis-19059	28	7	impact	impact	NOUN
bracis-19059	28	8	on	on	ADP
bracis-19059	28	9	the	the	DET
bracis-19059	28	10	structure	structure	NOUN
bracis-19059	28	11	and	and	CCONJ
bracis-19059	28	12	function	function	NOUN
bracis-19059	28	13	of	of	ADP
bracis-19059	28	14	proteins	protein	NOUN
bracis-19059	28	15	[	[	X
bracis-19059	28	16	17	17	NUM
bracis-19059	28	17	,	,	PUNCT
bracis-19059	28	18	19	19	NUM
bracis-19059	28	19	]	]	PUNCT
bracis-19059	28	20	.	.	PUNCT
bracis-19059	29	1	however	however	ADV
bracis-19059	29	2	,	,	PUNCT
bracis-19059	29	3	due	due	ADP
bracis-19059	29	4	to	to	ADP
bracis-19059	29	5	the	the	DET
bracis-19059	29	6	vast	vast	ADJ
bracis-19059	29	7	number	number	NOUN
bracis-19059	29	8	of	of	ADP
bracis-19059	29	9	possibilities	possibility	NOUN
bracis-19059	29	10	,	,	PUNCT
bracis-19059	29	11	it	it	PRON
bracis-19059	29	12	is	be	AUX
bracis-19059	29	13	impractical	impractical	ADJ
bracis-19059	29	14	to	to	PART
bracis-19059	29	15	experimentally	experimentally	ADV
bracis-19059	29	16	evaluate	evaluate	VERB
bracis-19059	29	17	the	the	DET
bracis-19059	29	18	impact	impact	NOUN
bracis-19059	29	19	of	of	ADP
bracis-19059	29	20	all	all	DET
bracis-19059	29	21	possible	possible	ADJ
bracis-19059	29	22	mutations	mutation	NOUN
bracis-19059	29	23	on	on	ADP
bracis-19059	29	24	protein	protein	NOUN
bracis-19059	29	25	structure	structure	NOUN
bracis-19059	29	26	and	and	CCONJ
bracis-19059	29	27	function	function	NOUN
bracis-19059	29	28	[	[	X
bracis-19059	29	29	25	25	NUM
bracis-19059	29	30	]	]	PUNCT
bracis-19059	29	31	.	.	PUNCT
bracis-19059	30	1	a	a	DET
bracis-19059	30	2	series	series	NOUN
bracis-19059	30	3	of	of	ADP
bracis-19059	30	4	computational	computational	ADJ
bracis-19059	30	5	tools	tool	NOUN
bracis-19059	30	6	have	have	AUX
bracis-19059	30	7	been	be	AUX
bracis-19059	30	8	developed	develop	VERB
bracis-19059	30	9	,	,	PUNCT
bracis-19059	30	10	with	with	ADP
bracis-19059	30	11	the	the	DET
bracis-19059	30	12	common	common	ADJ
bracis-19059	30	13	objective	objective	NOUN
bracis-19059	30	14	of	of	ADP
bracis-19059	30	15	predicting	predict	VERB
bracis-19059	30	16	the	the	DET
bracis-19059	30	17	effect	effect	NOUN
bracis-19059	30	18	of	of	ADP
bracis-19059	30	19	point	point	NOUN
bracis-19059	30	20	mutations	mutation	NOUN
bracis-19059	30	21	on	on	ADP
bracis-19059	30	22	the	the	DET
bracis-19059	30	23	structure	structure	NOUN
bracis-19059	30	24	of	of	ADP
bracis-19059	30	25	a	a	DET
bracis-19059	30	26	protein	protein	NOUN
bracis-19059	30	27	.	.	PUNCT
bracis-19059	31	1	in	in	ADP
bracis-19059	31	2	general	general	ADJ
bracis-19059	31	3	,	,	PUNCT
bracis-19059	31	4	prediction	prediction	NOUN
bracis-19059	31	5	tools	tool	NOUN
bracis-19059	31	6	are	be	AUX
bracis-19059	31	7	developed	develop	VERB
bracis-19059	31	8	and	and	CCONJ
bracis-19059	31	9	used	use	VERB
bracis-19059	31	10	by	by	ADP
bracis-19059	31	11	professionals	professional	NOUN
bracis-19059	31	12	from	from	ADP
bracis-19059	31	13	different	different	ADJ
bracis-19059	31	14	areas	area	NOUN
bracis-19059	31	15	who	who	PRON
bracis-19059	31	16	,	,	PUNCT
bracis-19059	31	17	generally	generally	ADV
bracis-19059	31	18	,	,	PUNCT
bracis-19059	31	19	do	do	AUX
bracis-19059	31	20	not	not	PART
bracis-19059	31	21	access	access	VERB
bracis-19059	31	22	the	the	DET
bracis-19059	31	23	same	same	ADJ
bracis-19059	31	24	tools	tool	NOUN
bracis-19059	31	25	for	for	ADP
bracis-19059	31	26	their	their	PRON
bracis-19059	31	27	analysis	analysis	NOUN
bracis-19059	31	28	,	,	PUNCT
bracis-19059	31	29	which	which	PRON
bracis-19059	31	30	implies	imply	VERB
bracis-19059	31	31	discrepancies	discrepancy	NOUN
bracis-19059	31	32	in	in	ADP
bracis-19059	31	33	results	result	NOUN
bracis-19059	31	34	and	and	CCONJ
bracis-19059	31	35	difficulties	difficulty	NOUN
bracis-19059	31	36	in	in	ADP
bracis-19059	31	37	interpretation	interpretation	NOUN
bracis-19059	31	38	,	,	PUNCT
bracis-19059	31	39	as	as	SCONJ
bracis-19059	31	40	they	they	PRON
bracis-19059	31	41	will	will	AUX
bracis-19059	31	42	have	have	VERB
bracis-19059	31	43	different	different	ADJ
bracis-19059	31	44	results	result	NOUN
bracis-19059	31	45	for	for	ADP
bracis-19059	31	46	the	the	DET
bracis-19059	31	47	same	same	ADJ
bracis-19059	31	48	data	data	NOUN
bracis-19059	31	49	entries	entry	NOUN
bracis-19059	31	50	.	.	PUNCT
bracis-19059	32	1	among	among	ADP
bracis-19059	32	2	the	the	DET
bracis-19059	32	3	many	many	ADJ
bracis-19059	32	4	tools	tool	NOUN
bracis-19059	32	5	available	available	ADJ
bracis-19059	32	6	we	we	PRON
bracis-19059	32	7	can	can	AUX
bracis-19059	32	8	cite	cite	VERB
bracis-19059	32	9	:	:	PUNCT
bracis-19059	32	10	dmutant	dmutant	ADJ
bracis-19059	32	11	[	[	X
bracis-19059	32	12	30	30	NUM
bracis-19059	32	13	]	]	PUNCT
bracis-19059	32	14	,	,	PUNCT
bracis-19059	32	15	foldx	foldx	NOUN
bracis-19059	32	16	[	[	X
bracis-19059	32	17	12	12	NUM
bracis-19059	32	18	]	]	PUNCT
bracis-19059	32	19	,	,	PUNCT
bracis-19059	32	20	i	i	PRON
bracis-19059	32	21	-	-	PUNCT
bracis-19059	32	22	mutant2.0	mutant2.0	PROPN
bracis-19059	33	1	[	[	X
bracis-19059	33	2	4	4	NUM
bracis-19059	33	3	]	]	PUNCT
bracis-19059	33	4	,	,	PUNCT
bracis-19059	33	5	cupsat	cupsat	VERB
bracis-19059	33	6	[	[	PRON
bracis-19059	33	7	17	17	NUM
bracis-19059	33	8	]	]	PUNCT
bracis-19059	33	9	,	,	PUNCT
bracis-19059	33	10	eris	eris	X
bracis-19059	34	1	[	[	X
bracis-19059	34	2	28	28	NUM
bracis-19059	34	3	]	]	PUNCT
bracis-19059	34	4	,	,	PUNCT
bracis-19059	34	5	i	i	PROPN
bracis-19059	34	6	-	-	PUNCT
bracis-19059	34	7	mutant3.0	mutant3.0	NOUN
bracis-19059	34	8	[	[	X
bracis-19059	34	9	5	5	NUM
bracis-19059	34	10	]	]	PUNCT
bracis-19059	34	11	,	,	PUNCT
bracis-19059	34	12	popmusic	popmusic	ADJ
bracis-19059	34	13	[	[	X
bracis-19059	34	14	7	7	NUM
bracis-19059	34	15	]	]	PUNCT
bracis-19059	34	16	,	,	PUNCT
bracis-19059	34	17	sdm	sdm	PROPN
bracis-19059	35	1	[	[	X
bracis-19059	35	2	25	25	NUM
bracis-19059	35	3	]	]	PUNCT
bracis-19059	35	4	,	,	PUNCT
bracis-19059	35	5	mcsm	mcsm	NOUN
bracis-19059	35	6	[	[	X
bracis-19059	35	7	18	18	NUM
bracis-19059	35	8	]	]	PUNCT
bracis-19059	35	9	,	,	PUNCT
bracis-19059	35	10	mupro	mupro	ADJ
bracis-19059	35	11	[	[	X
bracis-19059	35	12	6	6	NUM
bracis-19059	35	13	]	]	PUNCT
bracis-19059	35	14	,	,	PUNCT
bracis-19059	35	15	maestro	maestro	NOUN
bracis-19059	35	16	[	[	X
bracis-19059	35	17	14	14	NUM
bracis-19059	35	18	]	]	PUNCT
bracis-19059	35	19	,	,	PUNCT
bracis-19059	35	20	and	and	CCONJ
bracis-19059	35	21	duet	duet	NOUN
bracis-19059	35	22	[	[	X
bracis-19059	35	23	19	19	NUM
bracis-19059	35	24	]	]	PUNCT
bracis-19059	35	25	.	.	PUNCT
bracis-19059	36	1	this	this	PRON
bracis-19059	36	2	computationally	computationally	ADV
bracis-19059	36	3	predicting	predict	VERB
bracis-19059	36	4	the	the	DET
bracis-19059	36	5	impact	impact	NOUN
bracis-19059	36	6	on	on	ADP
bracis-19059	36	7	proteins	protein	NOUN
bracis-19059	36	8	structure	structure	NOUN
bracis-19059	36	9	,	,	PUNCT
bracis-19059	36	10	and	and	CCONJ
bracis-19059	36	11	function	function	NOUN
bracis-19059	36	12	,	,	PUNCT
bracis-19059	36	13	upon	upon	SCONJ
bracis-19059	36	14	point	point	NOUN
bracis-19059	36	15	mutations	mutation	NOUN
bracis-19059	36	16	is	be	AUX
bracis-19059	36	17	of	of	ADP
bracis-19059	36	18	great	great	ADJ
bracis-19059	36	19	scientific	scientific	ADJ
bracis-19059	36	20	and	and	CCONJ
bracis-19059	36	21	commercial	commercial	ADJ
bracis-19059	36	22	interest	interest	NOUN
bracis-19059	36	23	.	.	PUNCT
bracis-19059	37	1	one	one	NUM
bracis-19059	37	2	way	way	NOUN
bracis-19059	37	3	of	of	ADP
bracis-19059	37	4	performing	perform	VERB
bracis-19059	37	5	such	such	ADJ
bracis-19059	37	6	predictions	prediction	NOUN
bracis-19059	37	7	is	be	AUX
bracis-19059	37	8	to	to	PART
bracis-19059	37	9	compute	compute	VERB
bracis-19059	37	10	the	the	DET
bracis-19059	37	11	\(\vardelta	\(\vardelta	NOUN
bracis-19059	37	12	\vardelta	\vardelta	X
bracis-19059	37	13	g\	g\	PROPN
bracis-19059	37	14	)	)	PUNCT
bracis-19059	37	15	(	(	PUNCT
bracis-19059	37	16	variation	variation	NOUN
bracis-19059	37	17	in	in	ADP
bracis-19059	37	18	the	the	DET
bracis-19059	37	19	variation	variation	NOUN
bracis-19059	37	20	of	of	ADP
bracis-19059	37	21	the	the	DET
bracis-19059	37	22	free	free	ADJ
bracis-19059	37	23	energy	energy	NOUN
bracis-19059	37	24	)	)	PUNCT
bracis-19059	37	25	.	.	PUNCT
bracis-19059	38	1	however	however	ADV
bracis-19059	38	2	,	,	PUNCT
bracis-19059	38	3	the	the	DET
bracis-19059	38	4	existing	exist	VERB
bracis-19059	38	5	methods	method	NOUN
bracis-19059	38	6	and	and	CCONJ
bracis-19059	38	7	tools	tool	NOUN
bracis-19059	38	8	do	do	AUX
bracis-19059	38	9	not	not	PART
bracis-19059	38	10	always	always	ADV
bracis-19059	38	11	obtain	obtain	VERB
bracis-19059	38	12	similar	similar	ADJ
bracis-19059	38	13	results	result	NOUN
bracis-19059	38	14	for	for	ADP
bracis-19059	38	15	the	the	DET
bracis-19059	38	16	same	same	ADJ
bracis-19059	38	17	entries	entry	NOUN
bracis-19059	38	18	.	.	PUNCT
bracis-19059	39	1	this	this	DET
bracis-19059	39	2	differences	difference	NOUN
bracis-19059	39	3	in	in	ADP
bracis-19059	39	4	results	result	NOUN
bracis-19059	39	5	obtained	obtain	VERB
bracis-19059	39	6	from	from	ADP
bracis-19059	39	7	distinct	distinct	ADJ
bracis-19059	39	8	tools	tool	NOUN
bracis-19059	39	9	might	might	AUX
bracis-19059	39	10	impact	impact	VERB
bracis-19059	39	11	negatively	negatively	ADV
bracis-19059	39	12	in	in	ADP
bracis-19059	39	13	the	the	DET
bracis-19059	39	14	experiments	experiment	NOUN
bracis-19059	39	15	carried	carry	VERB
bracis-19059	39	16	out	out	ADP
bracis-19059	39	17	by	by	ADP
bracis-19059	39	18	researchers	researcher	NOUN
bracis-19059	39	19	.	.	PUNCT
bracis-19059	40	1	the	the	DET
bracis-19059	40	2	resulting	result	VERB
bracis-19059	40	3	\(\vardelta	\(\vardelta	NOUN
bracis-19059	40	4	\vardelta	\vardelta	X
bracis-19059	40	5	g\	g\	NOUN
bracis-19059	40	6	)	)	PUNCT
bracis-19059	40	7	from	from	ADP
bracis-19059	40	8	the	the	DET
bracis-19059	40	9	computational	computational	ADJ
bracis-19059	40	10	tools	tool	NOUN
bracis-19059	40	11	is	be	AUX
bracis-19059	40	12	usually	usually	ADV
bracis-19059	40	13	discretized	discretize	VERB
bracis-19059	40	14	in	in	ADP
bracis-19059	40	15	stabilizing	stabilizing	NOUN
bracis-19059	40	16	and	and	CCONJ
bracis-19059	40	17	destabilizing	destabilizing	NOUN
bracis-19059	40	18	and	and	CCONJ
bracis-19059	40	19	this	this	PRON
bracis-19059	40	20	is	be	AUX
bracis-19059	40	21	an	an	DET
bracis-19059	40	22	important	important	ADJ
bracis-19059	40	23	information	information	NOUN
bracis-19059	40	24	to	to	PART
bracis-19059	40	25	define	define	VERB
bracis-19059	40	26	whether	whether	SCONJ
bracis-19059	40	27	a	a	DET
bracis-19059	40	28	mutation	mutation	NOUN
bracis-19059	40	29	is	be	AUX
bracis-19059	40	30	viable	viable	ADJ
bracis-19059	40	31	or	or	CCONJ
bracis-19059	40	32	not	not	PART
bracis-19059	40	33	.	.	PUNCT
bracis-19059	41	1	in	in	ADP
bracis-19059	41	2	this	this	DET
bracis-19059	41	3	context	context	NOUN
bracis-19059	41	4	,	,	PUNCT
bracis-19059	41	5	where	where	SCONJ
bracis-19059	41	6	we	we	PRON
bracis-19059	41	7	have	have	VERB
bracis-19059	41	8	several	several	ADJ
bracis-19059	41	9	answers	answer	NOUN
bracis-19059	41	10	for	for	ADP
bracis-19059	41	11	the	the	DET
bracis-19059	41	12	same	same	ADJ
bracis-19059	41	13	problem	problem	NOUN
bracis-19059	41	14	,	,	PUNCT
bracis-19059	41	15	ensemble	ensemble	ADJ
bracis-19059	41	16	learning	learning	NOUN
bracis-19059	41	17	techniques	technique	NOUN
bracis-19059	41	18	can	can	AUX
bracis-19059	41	19	be	be	AUX
bracis-19059	41	20	a	a	DET
bracis-19059	41	21	good	good	ADJ
bracis-19059	41	22	alternative	alternative	NOUN
bracis-19059	41	23	.	.	PUNCT
bracis-19059	42	1	ensemble	ensemble	ADJ
bracis-19059	42	2	learning	learning	NOUN
bracis-19059	42	3	aims	aim	VERB
bracis-19059	42	4	to	to	PART
bracis-19059	42	5	aggregate	aggregate	VERB
bracis-19059	42	6	predictions	prediction	NOUN
bracis-19059	42	7	from	from	ADP
bracis-19059	42	8	different	different	ADJ
bracis-19059	42	9	classifier	classifier	NOUN
bracis-19059	42	10	models	model	NOUN
bracis-19059	42	11	in	in	ADP
bracis-19059	42	12	just	just	ADV
bracis-19059	42	13	one	one	NUM
bracis-19059	42	14	result	result	NOUN
bracis-19059	42	15	.	.	PUNCT
bracis-19059	43	1	these	these	DET
bracis-19059	43	2	combinations	combination	NOUN
bracis-19059	43	3	can	can	AUX
bracis-19059	43	4	be	be	AUX
bracis-19059	43	5	achieved	achieve	VERB
bracis-19059	43	6	in	in	ADP
bracis-19059	43	7	many	many	ADJ
bracis-19059	43	8	different	different	ADJ
bracis-19059	43	9	ways	way	NOUN
bracis-19059	43	10	,	,	PUNCT
bracis-19059	43	11	e.g.	e.g.	ADV
bracis-19059	43	12	,	,	PUNCT
bracis-19059	43	13	average	average	ADJ
bracis-19059	43	14	,	,	PUNCT
bracis-19059	43	15	major	major	ADJ
bracis-19059	43	16	voting	voting	NOUN
bracis-19059	43	17	,	,	PUNCT
bracis-19059	43	18	etc	etc	X
bracis-19059	43	19	.	.	X
bracis-19059	44	1	the	the	DET
bracis-19059	44	2	resulting	result	VERB
bracis-19059	44	3	ensemble	ensemble	ADJ
bracis-19059	44	4	classifier	classifier	NOUN
bracis-19059	44	5	usually	usually	ADV
bracis-19059	44	6	obtains	obtain	VERB
bracis-19059	44	7	better	well	ADJ
bracis-19059	44	8	results	result	NOUN
bracis-19059	44	9	than	than	ADP
bracis-19059	44	10	the	the	DET
bracis-19059	44	11	individual	individual	ADJ
bracis-19059	44	12	results	result	NOUN
bracis-19059	44	13	of	of	ADP
bracis-19059	44	14	the	the	DET
bracis-19059	44	15	classifiers	classifier	NOUN
bracis-19059	44	16	used	use	VERB
bracis-19059	44	17	in	in	ADP
bracis-19059	44	18	the	the	DET
bracis-19059	44	19	combination	combination	NOUN
bracis-19059	44	20	[	[	X
bracis-19059	44	21	27	27	NUM
bracis-19059	44	22	]	]	PUNCT
bracis-19059	44	23	.	.	PUNCT
bracis-19059	45	1	therefore	therefore	ADV
bracis-19059	45	2	,	,	PUNCT
bracis-19059	45	3	the	the	DET
bracis-19059	45	4	present	present	ADJ
bracis-19059	45	5	work	work	NOUN
bracis-19059	45	6	proposes	propose	VERB
bracis-19059	45	7	the	the	DET
bracis-19059	45	8	application	application	NOUN
bracis-19059	45	9	of	of	ADP
bracis-19059	45	10	ensemble	ensemble	ADJ
bracis-19059	45	11	learning	learning	NOUN
bracis-19059	45	12	to	to	PART
bracis-19059	45	13	aggregate	aggregate	VERB
bracis-19059	45	14	the	the	DET
bracis-19059	45	15	protein	protein	NOUN
bracis-19059	45	16	stability	stability	NOUN
bracis-19059	45	17	predictions	prediction	NOUN
bracis-19059	45	18	of	of	ADP
bracis-19059	45	19	individual	individual	ADJ
bracis-19059	45	20	tools	tool	NOUN
bracis-19059	45	21	.	.	PUNCT
bracis-19059	46	1	techniques	technique	NOUN
bracis-19059	46	2	of	of	ADP
bracis-19059	46	3	stacking	stacking	NOUN
bracis-19059	46	4	,	,	PUNCT
bracis-19059	46	5	bagging	bagging	NOUN
bracis-19059	46	6	,	,	PUNCT
bracis-19059	46	7	and	and	CCONJ
bracis-19059	46	8	boosting	boost	VERB
bracis-19059	46	9	as	as	ADV
bracis-19059	46	10	well	well	ADV
bracis-19059	46	11	as	as	ADP
bracis-19059	46	12	different	different	ADJ
bracis-19059	46	13	machine	machine	NOUN
bracis-19059	46	14	learning	learn	VERB
bracis-19059	46	15	algorithms	algorithm	NOUN
bracis-19059	46	16	as	as	SCONJ
bracis-19059	46	17	combiner	combiner	NOUN
bracis-19059	46	18	function	function	NOUN
bracis-19059	46	19	are	be	AUX
bracis-19059	46	20	explored	explore	VERB
bracis-19059	46	21	.	.	PUNCT
bracis-19059	47	1	the	the	DET
bracis-19059	47	2	ensemble	ensemble	ADJ
bracis-19059	47	3	models	model	NOUN
bracis-19059	47	4	were	be	AUX
bracis-19059	47	5	trained	train	VERB
bracis-19059	47	6	and	and	CCONJ
bracis-19059	47	7	validated	validate	VERB
bracis-19059	47	8	using	use	VERB
bracis-19059	47	9	data	datum	NOUN
bracis-19059	47	10	from	from	ADP
bracis-19059	47	11	protherm	protherm	NOUN
bracis-19059	47	12	[	[	X
bracis-19059	47	13	2	2	NUM
bracis-19059	47	14	]	]	PUNCT
bracis-19059	47	15	,	,	PUNCT
bracis-19059	47	16	a	a	DET
bracis-19059	47	17	database	database	NOUN
bracis-19059	47	18	composed	compose	VERB
bracis-19059	47	19	by	by	ADP
bracis-19059	47	20	sequence	sequence	NOUN
bracis-19059	47	21	and	and	CCONJ
bracis-19059	47	22	structural	structural	ADJ
bracis-19059	47	23	information	information	NOUN
bracis-19059	47	24	obtained	obtain	VERB
bracis-19059	47	25	from	from	ADP
bracis-19059	47	26	experimental	experimental	ADJ
bracis-19059	47	27	methods	method	NOUN
bracis-19059	47	28	for	for	ADP
bracis-19059	47	29	wild	wild	ADJ
bracis-19059	47	30	-	-	PUNCT
bracis-19059	47	31	type	type	NOUN
bracis-19059	47	32	and	and	CCONJ
bracis-19059	47	33	mutant	mutant	ADJ
bracis-19059	47	34	proteins	protein	NOUN
bracis-19059	47	35	.	.	PUNCT
bracis-19059	48	1	the	the	DET
bracis-19059	48	2	paper	paper	NOUN
bracis-19059	48	3	is	be	AUX
bracis-19059	48	4	organized	organize	VERB
bracis-19059	48	5	as	as	SCONJ
bracis-19059	48	6	follows	follow	VERB
bracis-19059	48	7	:	:	PUNCT
bracis-19059	48	8	sect	sect	NOUN
bracis-19059	48	9	.	.	PUNCT
bracis-19059	48	10	 	 	SPACE
bracis-19059	49	1	2	2	NUM
bracis-19059	49	2	presents	present	NOUN
bracis-19059	49	3	bioinformatics	bioinformatics	NOUN
bracis-19059	49	4	and	and	CCONJ
bracis-19059	49	5	machine	machine	NOUN
bracis-19059	49	6	learning	learn	VERB
bracis-19059	49	7	brief	brief	ADJ
bracis-19059	49	8	concepts	concept	NOUN
bracis-19059	49	9	related	relate	VERB
bracis-19059	49	10	to	to	ADP
bracis-19059	49	11	this	this	DET
bracis-19059	49	12	purpose	purpose	NOUN
bracis-19059	49	13	;	;	PUNCT
bracis-19059	49	14	sect	sect	NOUN
bracis-19059	49	15	.	.	PUNCT
bracis-19059	49	16	 	 	SPACE
bracis-19059	49	17	3	3	NUM
bracis-19059	49	18	detailed	detail	VERB
bracis-19059	49	19	the	the	DET
bracis-19059	49	20	individual	individual	ADJ
bracis-19059	49	21	tools	tool	NOUN
bracis-19059	49	22	used	use	VERB
bracis-19059	49	23	on	on	ADP
bracis-19059	49	24	the	the	DET
bracis-19059	49	25	ensemble	ensemble	ADJ
bracis-19059	49	26	;	;	PUNCT
bracis-19059	49	27	sect	sect	NOUN
bracis-19059	49	28	.	.	PUNCT
bracis-19059	49	29	 	 	SPACE
bracis-19059	50	1	4	4	NUM
bracis-19059	50	2	describes	describe	VERB
bracis-19059	50	3	the	the	DET
bracis-19059	50	4	proposed	propose	VERB
bracis-19059	50	5	methodology	methodology	NOUN
bracis-19059	50	6	;	;	PUNCT
bracis-19059	50	7	sect	sect	NOUN
bracis-19059	50	8	.	.	PUNCT
bracis-19059	50	9	 	 	SPACE
bracis-19059	51	1	5	5	NUM
bracis-19059	51	2	presents	present	VERB
bracis-19059	51	3	the	the	DET
bracis-19059	51	4	results	result	NOUN
bracis-19059	51	5	and	and	CCONJ
bracis-19059	51	6	discussion	discussion	NOUN
bracis-19059	51	7	and	and	CCONJ
bracis-19059	51	8	finally	finally	ADV
bracis-19059	51	9	sect	sect	VERB
bracis-19059	51	10	.	.	PUNCT
bracis-19059	51	11	 	 	SPACE
bracis-19059	51	12	6	6	NUM
bracis-19059	51	13	concludes	conclude	VERB
bracis-19059	51	14	the	the	DET
bracis-19059	51	15	paper	paper	NOUN
bracis-19059	51	16	and	and	CCONJ
bracis-19059	51	17	show	show	VERB
bracis-19059	51	18	some	some	DET
bracis-19059	51	19	future	future	ADJ
bracis-19059	51	20	work	work	NOUN
bracis-19059	51	21	.	.	PUNCT
bracis-19059	52	1	2	2	NUM
bracis-19059	52	2	background	background	NOUN
bracis-19059	52	3	2.1	2.1	NUM
bracis-19059	52	4	point	point	NOUN
bracis-19059	52	5	mutations	mutation	NOUN
bracis-19059	52	6	and	and	CCONJ
bracis-19059	52	7	 	 	SPACE
bracis-19059	52	8	their	their	PRON
bracis-19059	52	9	effects	effect	NOUN
bracis-19059	52	10	on	on	ADP
bracis-19059	52	11	 	 	SPACE
bracis-19059	52	12	protein	protein	NOUN
bracis-19059	52	13	structures	structure	NOUN
bracis-19059	52	14	dna	dna	NOUN
bracis-19059	52	15	is	be	AUX
bracis-19059	52	16	formed	form	VERB
bracis-19059	52	17	by	by	ADP
bracis-19059	52	18	a	a	DET
bracis-19059	52	19	sequence	sequence	NOUN
bracis-19059	52	20	of	of	ADP
bracis-19059	52	21	molecules	molecule	NOUN
bracis-19059	52	22	,	,	PUNCT
bracis-19059	52	23	or	or	CCONJ
bracis-19059	52	24	base	base	NOUN
bracis-19059	52	25	pairs	pair	NOUN
bracis-19059	52	26	.	.	PUNCT
bracis-19059	53	1	some	some	DET
bracis-19059	53	2	parts	part	NOUN
bracis-19059	53	3	of	of	ADP
bracis-19059	53	4	dna	dna	PROPN
bracis-19059	53	5	are	be	AUX
bracis-19059	53	6	transcript	transcript	NOUN
bracis-19059	53	7	as	as	ADP
bracis-19059	53	8	rna	rna	NOUN
bracis-19059	53	9	which	which	PRON
bracis-19059	53	10	in	in	ADP
bracis-19059	53	11	turn	turn	NOUN
bracis-19059	53	12	is	be	AUX
bracis-19059	53	13	translated	translate	VERB
bracis-19059	53	14	as	as	ADP
bracis-19059	53	15	a	a	DET
bracis-19059	53	16	protein	protein	NOUN
bracis-19059	53	17	.	.	PUNCT
bracis-19059	54	1	in	in	ADP
bracis-19059	54	2	translation	translation	NOUN
bracis-19059	54	3	,	,	PUNCT
bracis-19059	54	4	each	each	DET
bracis-19059	54	5	three	three	NUM
bracis-19059	54	6	bases	basis	NOUN
bracis-19059	54	7	of	of	ADP
bracis-19059	54	8	rna	rna	NOUN
bracis-19059	54	9	is	be	AUX
bracis-19059	54	10	translated	translate	VERB
bracis-19059	54	11	as	as	ADP
bracis-19059	54	12	one	one	NUM
bracis-19059	54	13	amino	amino	NOUN
bracis-19059	54	14	acid	acid	NOUN
bracis-19059	54	15	.	.	PUNCT
bracis-19059	55	1	the	the	DET
bracis-19059	55	2	order	order	NOUN
bracis-19059	55	3	of	of	ADP
bracis-19059	55	4	amino	amino	ADJ
bracis-19059	55	5	acids	acid	NOUN
bracis-19059	55	6	determines	determine	VERB
bracis-19059	55	7	the	the	DET
bracis-19059	55	8	3d	3d	NUM
bracis-19059	55	9	structure	structure	NOUN
bracis-19059	55	10	and	and	CCONJ
bracis-19059	55	11	consequently	consequently	ADV
bracis-19059	55	12	the	the	DET
bracis-19059	55	13	function	function	NOUN
bracis-19059	55	14	of	of	ADP
bracis-19059	55	15	proteins	protein	NOUN
bracis-19059	55	16	.	.	PUNCT
bracis-19059	56	1	a	a	DET
bracis-19059	56	2	point	point	NOUN
bracis-19059	56	3	mutation	mutation	NOUN
bracis-19059	56	4	is	be	AUX
bracis-19059	56	5	when	when	SCONJ
bracis-19059	56	6	a	a	DET
bracis-19059	56	7	single	single	ADJ
bracis-19059	56	8	base	base	NOUN
bracis-19059	56	9	pair	pair	NOUN
bracis-19059	56	10	is	be	AUX
bracis-19059	56	11	exchanged	exchange	VERB
bracis-19059	56	12	[	[	X
bracis-19059	56	13	1	1	NUM
bracis-19059	56	14	,	,	PUNCT
bracis-19059	56	15	29	29	NUM
bracis-19059	56	16	]	]	PUNCT
bracis-19059	56	17	.	.	PUNCT
bracis-19059	57	1	they	they	PRON
bracis-19059	57	2	can	can	AUX
bracis-19059	57	3	be	be	AUX
bracis-19059	57	4	:	:	PUNCT
bracis-19059	57	5	i	i	NOUN
bracis-19059	57	6	)	)	PUNCT
bracis-19059	57	7	silent	silent	ADJ
bracis-19059	57	8	:	:	PUNCT
bracis-19059	57	9	when	when	SCONJ
bracis-19059	57	10	the	the	DET
bracis-19059	57	11	resulting	result	VERB
bracis-19059	57	12	amino	amino	NOUN
bracis-19059	57	13	acid	acid	NOUN
bracis-19059	57	14	is	be	AUX
bracis-19059	57	15	the	the	DET
bracis-19059	57	16	same	same	ADJ
bracis-19059	57	17	,	,	PUNCT
bracis-19059	57	18	no	no	DET
bracis-19059	57	19	changes	change	NOUN
bracis-19059	57	20	in	in	ADP
bracis-19059	57	21	the	the	DET
bracis-19059	57	22	resulting	result	VERB
bracis-19059	57	23	protein	protein	NOUN
bracis-19059	57	24	;	;	PUNCT
bracis-19059	57	25	ii	ii	X
bracis-19059	57	26	)	)	PUNCT
bracis-19059	57	27	missense	missense	NOUN
bracis-19059	57	28	:	:	PUNCT
bracis-19059	57	29	when	when	SCONJ
bracis-19059	57	30	the	the	DET
bracis-19059	57	31	resulting	result	VERB
bracis-19059	57	32	amino	amino	NOUN
bracis-19059	57	33	acid	acid	NOUN
bracis-19059	57	34	is	be	AUX
bracis-19059	57	35	different	different	ADJ
bracis-19059	57	36	from	from	ADP
bracis-19059	57	37	the	the	DET
bracis-19059	57	38	original	original	NOUN
bracis-19059	57	39	hence	hence	ADV
bracis-19059	57	40	the	the	DET
bracis-19059	57	41	protein	protein	NOUN
bracis-19059	57	42	is	be	AUX
bracis-19059	57	43	different	different	ADJ
bracis-19059	57	44	and	and	CCONJ
bracis-19059	57	45	iii	iii	NOUN
bracis-19059	57	46	)	)	PUNCT
bracis-19059	57	47	nonsense	nonsense	NOUN
bracis-19059	57	48	:	:	PUNCT
bracis-19059	57	49	the	the	DET
bracis-19059	57	50	resulting	result	VERB
bracis-19059	57	51	mutations	mutation	NOUN
bracis-19059	57	52	indicate	indicate	VERB
bracis-19059	57	53	a	a	DET
bracis-19059	57	54	stop	stop	NOUN
bracis-19059	57	55	signal	signal	NOUN
bracis-19059	57	56	,	,	PUNCT
bracis-19059	57	57	again	again	ADV
bracis-19059	57	58	the	the	DET
bracis-19059	57	59	result	result	NOUN
bracis-19059	57	60	is	be	AUX
bracis-19059	57	61	a	a	DET
bracis-19059	57	62	modified	modify	VERB
bracis-19059	57	63	protein	protein	NOUN
bracis-19059	57	64	.	.	PUNCT
bracis-19059	58	1	in	in	ADP
bracis-19059	58	2	this	this	DET
bracis-19059	58	3	study	study	NOUN
bracis-19059	58	4	,	,	PUNCT
bracis-19059	58	5	the	the	DET
bracis-19059	58	6	focus	focus	NOUN
bracis-19059	58	7	is	be	AUX
bracis-19059	58	8	on	on	ADP
bracis-19059	58	9	point	point	NOUN
bracis-19059	58	10	mutations	mutation	NOUN
bracis-19059	58	11	that	that	PRON
bracis-19059	58	12	results	result	VERB
bracis-19059	58	13	in	in	ADP
bracis-19059	58	14	an	an	DET
bracis-19059	58	15	exchange	exchange	NOUN
bracis-19059	58	16	of	of	ADP
bracis-19059	58	17	amino	amino	ADJ
bracis-19059	58	18	acids	acid	NOUN
bracis-19059	58	19	and	and	CCONJ
bracis-19059	58	20	thus	thus	ADV
bracis-19059	58	21	in	in	ADP
bracis-19059	58	22	a	a	DET
bracis-19059	58	23	modified	modify	VERB
bracis-19059	58	24	protein	protein	NOUN
bracis-19059	58	25	.	.	PUNCT
bracis-19059	59	1	2.2	2.2	NUM
bracis-19059	59	2	gibbs	gibbs	PROPN
bracis-19059	59	3	free	free	ADJ
bracis-19059	59	4	energy	energy	NOUN
bracis-19059	59	5	(	(	PUNCT
bracis-19059	59	6	g	g	NOUN
bracis-19059	59	7	)	)	PUNCT
bracis-19059	59	8	gibbs	gibbs	PROPN
bracis-19059	59	9	free	free	ADJ
bracis-19059	59	10	energy	energy	NOUN
bracis-19059	59	11	is	be	AUX
bracis-19059	59	12	stabilized	stabilize	VERB
bracis-19059	59	13	when	when	SCONJ
bracis-19059	59	14	the	the	DET
bracis-19059	59	15	protein	protein	NOUN
bracis-19059	59	16	is	be	AUX
bracis-19059	59	17	in	in	ADP
bracis-19059	59	18	constant	constant	ADJ
bracis-19059	59	19	equilibrium	equilibrium	NOUN
bracis-19059	59	20	,	,	PUNCT
bracis-19059	59	21	both	both	CCONJ
bracis-19059	59	22	in	in	ADP
bracis-19059	59	23	pressure	pressure	NOUN
bracis-19059	59	24	and	and	CCONJ
bracis-19059	59	25	temperature	temperature	NOUN
bracis-19059	59	26	.	.	PUNCT
bracis-19059	60	1	therefore	therefore	ADV
bracis-19059	60	2	,	,	PUNCT
bracis-19059	60	3	the	the	DET
bracis-19059	60	4	protein	protein	NOUN
bracis-19059	60	5	in	in	ADP
bracis-19059	60	6	its	its	PRON
bracis-19059	60	7	native	native	ADJ
bracis-19059	60	8	state	state	NOUN
bracis-19059	60	9	(	(	PUNCT
bracis-19059	60	10	or	or	CCONJ
bracis-19059	60	11	wild	wild	ADJ
bracis-19059	60	12	type	type	NOUN
bracis-19059	60	13	,	,	PUNCT
bracis-19059	60	14	wt	wt	NOUN
bracis-19059	60	15	)	)	PUNCT
bracis-19059	60	16	has	have	VERB
bracis-19059	60	17	a	a	DET
bracis-19059	60	18	certain	certain	ADJ
bracis-19059	60	19	amount	amount	NOUN
bracis-19059	60	20	of	of	ADP
bracis-19059	60	21	energy	energy	NOUN
bracis-19059	60	22	\(g_{\text	\(g_{\text	NOUN
bracis-19059	60	23	{	{	PUNCT
bracis-19059	60	24	wt}}\	wt}}\	PROPN
bracis-19059	60	25	)	)	PUNCT
bracis-19059	60	26	.	.	PUNCT
bracis-19059	61	1	when	when	SCONJ
bracis-19059	61	2	the	the	DET
bracis-19059	61	3	protein	protein	NOUN
bracis-19059	61	4	folding	fold	VERB
bracis-19059	61	5	process	process	NOUN
bracis-19059	61	6	occurs	occur	VERB
bracis-19059	61	7	,	,	PUNCT
bracis-19059	61	8	the	the	DET
bracis-19059	61	9	gibbs	gibbs	PROPN
bracis-19059	61	10	free	free	PROPN
bracis-19059	61	11	energy	energy	NOUN
bracis-19059	61	12	undergoes	undergo	VERB
bracis-19059	61	13	a	a	DET
bracis-19059	61	14	variation	variation	NOUN
bracis-19059	61	15	,	,	PUNCT
bracis-19059	61	16	providing	provide	VERB
bracis-19059	61	17	a	a	DET
bracis-19059	61	18	variation	variation	NOUN
bracis-19059	61	19	of	of	ADP
bracis-19059	61	20	energy	energy	NOUN
bracis-19059	61	21	\(\vardelta	\(\vardelta	NOUN
bracis-19059	61	22	g_{\text	g_{\text	X
bracis-19059	61	23	{	{	PUNCT
bracis-19059	61	24	wt}}\	wt}}\	PROPN
bracis-19059	61	25	)	)	PUNCT
bracis-19059	61	26	.	.	PUNCT
bracis-19059	62	1	in	in	ADP
bracis-19059	62	2	the	the	DET
bracis-19059	62	3	same	same	ADJ
bracis-19059	62	4	way	way	NOUN
bracis-19059	62	5	that	that	PRON
bracis-19059	62	6	,	,	PUNCT
bracis-19059	62	7	if	if	SCONJ
bracis-19059	62	8	we	we	PRON
bracis-19059	62	9	analyze	analyze	VERB
bracis-19059	62	10	the	the	DET
bracis-19059	62	11	same	same	ADJ
bracis-19059	62	12	protein	protein	NOUN
bracis-19059	62	13	in	in	ADP
bracis-19059	62	14	a	a	DET
bracis-19059	62	15	mutated	mutate	VERB
bracis-19059	62	16	state	state	NOUN
bracis-19059	62	17	,	,	PUNCT
bracis-19059	62	18	we	we	PRON
bracis-19059	62	19	have	have	VERB
bracis-19059	62	20	,	,	PUNCT
bracis-19059	62	21	in	in	ADP
bracis-19059	62	22	its	its	PRON
bracis-19059	62	23	equilibrium	equilibrium	NOUN
bracis-19059	62	24	,	,	PUNCT
bracis-19059	62	25	an	an	DET
bracis-19059	62	26	energy	energy	NOUN
bracis-19059	62	27	\(g_{\text	\(g_{\text	NOUN
bracis-19059	62	28	{	{	PUNCT
bracis-19059	62	29	mutant}}\	mutant}}\	PROPN
bracis-19059	62	30	)	)	PUNCT
bracis-19059	62	31	and	and	CCONJ
bracis-19059	62	32	,	,	PUNCT
bracis-19059	62	33	when	when	SCONJ
bracis-19059	62	34	this	this	DET
bracis-19059	62	35	mutated	mutate	VERB
bracis-19059	62	36	protein	protein	NOUN
bracis-19059	62	37	folds	fold	NOUN
bracis-19059	62	38	,	,	PUNCT
bracis-19059	62	39	we	we	PRON
bracis-19059	62	40	can	can	AUX
bracis-19059	62	41	calculate	calculate	VERB
bracis-19059	62	42	the	the	DET
bracis-19059	62	43	\(\vardelta	\(\vardelta	NOUN
bracis-19059	62	44	g_{\text	g_{\text	NOUN
bracis-19059	62	45	{	{	PUNCT
bracis-19059	62	46	mutant	mutant	NOUN
bracis-19059	62	47	}	}	PUNCT
bracis-19059	62	48	}	}	PUNCT
bracis-19059	62	49	\	\	NOUN
bracis-19059	62	50	)	)	PUNCT
bracis-19059	62	51	.	.	PUNCT
bracis-19059	63	1	then	then	ADV
bracis-19059	63	2	,	,	PUNCT
bracis-19059	63	3	with	with	ADP
bracis-19059	63	4	the	the	DET
bracis-19059	63	5	folding	folding	NOUN
bracis-19059	63	6	of	of	ADP
bracis-19059	63	7	the	the	DET
bracis-19059	63	8	native	native	ADJ
bracis-19059	63	9	and	and	CCONJ
bracis-19059	63	10	mutant	mutant	ADJ
bracis-19059	63	11	proteins	protein	NOUN
bracis-19059	63	12	,	,	PUNCT
bracis-19059	63	13	one	one	PRON
bracis-19059	63	14	can	can	AUX
bracis-19059	63	15	calculate	calculate	VERB
bracis-19059	63	16	the	the	DET
bracis-19059	63	17	\(\vardelta	\(\vardelta	NOUN
bracis-19059	63	18	\vardelta	\vardelta	X
bracis-19059	63	19	g\	g\	NOUN
bracis-19059	63	20	)	)	PUNCT
bracis-19059	63	21	,	,	PUNCT
bracis-19059	63	22	which	which	PRON
bracis-19059	63	23	is	be	AUX
bracis-19059	63	24	calculated	calculate	VERB
bracis-19059	63	25	using	use	VERB
bracis-19059	63	26	the	the	DET
bracis-19059	63	27	eq	eq	NOUN
bracis-19059	63	28	.	.	PUNCT
bracis-19059	63	29	 	 	SPACE
bracis-19059	63	30	1	1	NUM
bracis-19059	64	1	[	[	X
bracis-19059	64	2	10	10	NUM
bracis-19059	64	3	,	,	PUNCT
bracis-19059	64	4	21	21	NUM
bracis-19059	64	5	]	]	PUNCT
bracis-19059	64	6	.	.	PUNCT
bracis-19059	65	1	the	the	DET
bracis-19059	65	2	\(\vardelta	\(\vardelta	NOUN
bracis-19059	65	3	\vardelta	\vardelta	X
bracis-19059	65	4	g\	g\	NOUN
bracis-19059	65	5	)	)	PUNCT
bracis-19059	65	6	is	be	AUX
bracis-19059	65	7	a	a	DET
bracis-19059	65	8	metric	metric	NOUN
bracis-19059	65	9	for	for	ADP
bracis-19059	65	10	predicting	predict	VERB
bracis-19059	65	11	how	how	SCONJ
bracis-19059	65	12	a	a	DET
bracis-19059	65	13	single	single	ADJ
bracis-19059	65	14	-	-	PUNCT
bracis-19059	65	15	point	point	NOUN
bracis-19059	65	16	mutation	mutation	NOUN
bracis-19059	65	17	affects	affect	VERB
bracis-19059	65	18	protein	protein	NOUN
bracis-19059	65	19	stability	stability	NOUN
bracis-19059	65	20	.	.	PUNCT
bracis-19059	66	1	with	with	ADP
bracis-19059	66	2	this	this	PRON
bracis-19059	66	3	,	,	PUNCT
bracis-19059	66	4	the	the	DET
bracis-19059	66	5	present	present	ADJ
bracis-19059	66	6	work	work	NOUN
bracis-19059	66	7	uses	use	VERB
bracis-19059	66	8	the	the	DET
bracis-19059	66	9	\(\vardelta	\(\vardelta	NOUN
bracis-19059	66	10	\vardelta	\vardelta	X
bracis-19059	66	11	g\	g\	NOUN
bracis-19059	66	12	)	)	PUNCT
bracis-19059	66	13	as	as	SCONJ
bracis-19059	66	14	the	the	DET
bracis-19059	66	15	main	main	ADJ
bracis-19059	66	16	attribute	attribute	NOUN
bracis-19059	66	17	to	to	PART
bracis-19059	66	18	be	be	AUX
bracis-19059	66	19	evaluated	evaluate	VERB
bracis-19059	66	20	,	,	PUNCT
bracis-19059	66	21	where	where	SCONJ
bracis-19059	66	22	the	the	DET
bracis-19059	66	23	unit	unit	NOUN
bracis-19059	66	24	\(\text	\(\text	NOUN
bracis-19059	66	25	{	{	PUNCT
bracis-19059	66	26	kcal	kcal	PROPN
bracis-19059	66	27	/	/	SYM
bracis-19059	66	28	mol}\	mol}\	PROPN
bracis-19059	66	29	)	)	PUNCT
bracis-19059	66	30	is	be	AUX
bracis-19059	66	31	used	use	VERB
bracis-19059	66	32	for	for	ADP
bracis-19059	66	33	the	the	DET
bracis-19059	66	34	quantitative	quantitative	ADJ
bracis-19059	66	35	values	value	NOUN
bracis-19059	66	36	.	.	PUNCT
bracis-19059	67	1	$	$	SYM
bracis-19059	67	2	$	$	SYM
bracis-19059	67	3	\begin{aligned	\begin{aligne	VERB
bracis-19059	67	4	}	}	PUNCT
bracis-19059	67	5	\vardelta	\vardelta	NOUN
bracis-19059	67	6	\vardelta	\vardelta	NOUN
bracis-19059	67	7	g	g	NOUN
bracis-19059	67	8	=	=	PUNCT
bracis-19059	67	9	\vardelta	\vardelta	NOUN
bracis-19059	67	10	g_{\text	g_{\text	NOUN
bracis-19059	67	11	{	{	PUNCT
bracis-19059	67	12	wt	wt	NOUN
bracis-19059	67	13	}	}	PUNCT
bracis-19059	67	14	}	}	PUNCT
bracis-19059	67	15	\vardelta	\vardelta	NOUN
bracis-19059	67	16	g_{\text	g_{\text	NOUN
bracis-19059	67	17	{	{	PUNCT
bracis-19059	67	18	mutant	mutant	NOUN
bracis-19059	67	19	}	}	PUNCT
bracis-19059	67	20	}	}	PUNCT
bracis-19059	67	21	\end{aligned}$$	\end{aligned}$$	X
bracis-19059	67	22	(	(	PUNCT
bracis-19059	67	23	1	1	NUM
bracis-19059	67	24	)	)	PUNCT
bracis-19059	67	25	2.3	2.3	NUM
bracis-19059	67	26	supervised	supervised	ADJ
bracis-19059	67	27	machine	machine	NOUN
bracis-19059	67	28	learning	learn	VERB
bracis-19059	67	29	machine	machine	NOUN
bracis-19059	67	30	learning	learning	NOUN
bracis-19059	67	31	(	(	PUNCT
bracis-19059	67	32	ml	ml	NOUN
bracis-19059	67	33	)	)	PUNCT
bracis-19059	67	34	investigates	investigate	VERB
bracis-19059	67	35	how	how	SCONJ
bracis-19059	67	36	computers	computer	NOUN
bracis-19059	67	37	can	can	AUX
bracis-19059	67	38	learn	learn	VERB
bracis-19059	67	39	based	base	VERB
bracis-19059	67	40	on	on	ADP
bracis-19059	67	41	data	datum	NOUN
bracis-19059	67	42	and	and	CCONJ
bracis-19059	67	43	has	have	AUX
bracis-19059	67	44	proven	prove	VERB
bracis-19059	67	45	to	to	PART
bracis-19059	67	46	be	be	AUX
bracis-19059	67	47	of	of	ADP
bracis-19059	67	48	great	great	ADJ
bracis-19059	67	49	practical	practical	ADJ
bracis-19059	67	50	value	value	NOUN
bracis-19059	67	51	in	in	ADP
bracis-19059	67	52	a	a	DET
bracis-19059	67	53	variety	variety	NOUN
bracis-19059	67	54	of	of	ADP
bracis-19059	67	55	application	application	NOUN
bracis-19059	67	56	domains	domain	NOUN
bracis-19059	67	57	[	[	X
bracis-19059	67	58	13	13	NUM
bracis-19059	67	59	]	]	PUNCT
bracis-19059	67	60	.	.	PUNCT
bracis-19059	68	1	supervised	supervised	ADJ
bracis-19059	68	2	learning	learning	NOUN
bracis-19059	68	3	is	be	AUX
bracis-19059	68	4	the	the	DET
bracis-19059	68	5	ml	ml	PROPN
bracis-19059	68	6	task	task	NOUN
bracis-19059	68	7	of	of	ADP
bracis-19059	68	8	learning	learn	VERB
bracis-19059	68	9	a	a	DET
bracis-19059	68	10	model	model	NOUN
bracis-19059	68	11	(	(	PUNCT
bracis-19059	68	12	or	or	CCONJ
bracis-19059	68	13	function	function	NOUN
bracis-19059	68	14	)	)	PUNCT
bracis-19059	68	15	that	that	PRON
bracis-19059	68	16	maps	map	VERB
bracis-19059	68	17	an	an	DET
bracis-19059	68	18	input	input	NOUN
bracis-19059	68	19	to	to	ADP
bracis-19059	68	20	an	an	DET
bracis-19059	68	21	output	output	NOUN
bracis-19059	68	22	based	base	VERB
bracis-19059	68	23	on	on	ADP
bracis-19059	68	24	example	example	NOUN
bracis-19059	68	25	input	input	NOUN
bracis-19059	68	26	-	-	PUNCT
bracis-19059	68	27	output	output	NOUN
bracis-19059	68	28	pairs	pair	NOUN
bracis-19059	68	29	.	.	PUNCT
bracis-19059	69	1	thus	thus	ADV
bracis-19059	69	2	,	,	PUNCT
bracis-19059	69	3	the	the	DET
bracis-19059	69	4	objective	objective	NOUN
bracis-19059	69	5	of	of	ADP
bracis-19059	69	6	these	these	DET
bracis-19059	69	7	tasks	task	NOUN
bracis-19059	69	8	is	be	AUX
bracis-19059	69	9	to	to	PART
bracis-19059	69	10	predict	predict	VERB
bracis-19059	69	11	the	the	DET
bracis-19059	69	12	value	value	NOUN
bracis-19059	69	13	of	of	ADP
bracis-19059	69	14	a	a	DET
bracis-19059	69	15	particular	particular	ADJ
bracis-19059	69	16	attribute	attribute	NOUN
bracis-19059	69	17	(	(	PUNCT
bracis-19059	69	18	target	target	NOUN
bracis-19059	69	19	)	)	PUNCT
bracis-19059	69	20	based	base	VERB
bracis-19059	69	21	on	on	ADP
bracis-19059	69	22	the	the	DET
bracis-19059	69	23	values	value	NOUN
bracis-19059	69	24	of	of	ADP
bracis-19059	69	25	other	other	ADJ
bracis-19059	69	26	attributes	attribute	NOUN
bracis-19059	69	27	(	(	PUNCT
bracis-19059	69	28	explanatory	explanatory	ADJ
bracis-19059	69	29	or	or	CCONJ
bracis-19059	69	30	independent	independent	ADJ
bracis-19059	69	31	variables	variable	NOUN
bracis-19059	69	32	)	)	PUNCT
bracis-19059	70	1	[	[	X
bracis-19059	70	2	22	22	NUM
bracis-19059	70	3	]	]	PUNCT
bracis-19059	70	4	.	.	PUNCT
bracis-19059	71	1	since	since	SCONJ
bracis-19059	71	2	the	the	DET
bracis-19059	71	3	data	datum	NOUN
bracis-19059	71	4	considered	consider	VERB
bracis-19059	71	5	in	in	ADP
bracis-19059	71	6	this	this	DET
bracis-19059	71	7	work	work	NOUN
bracis-19059	71	8	has	have	VERB
bracis-19059	71	9	a	a	DET
bracis-19059	71	10	target	target	NOUN
bracis-19059	71	11	value	value	NOUN
bracis-19059	71	12	,	,	PUNCT
bracis-19059	71	13	the	the	DET
bracis-19059	71	14	\(\vardelta	\(\vardelta	NOUN
bracis-19059	71	15	\vardelta	\vardelta	X
bracis-19059	71	16	g\	g\	NOUN
bracis-19059	71	17	)	)	PUNCT
bracis-19059	71	18	,	,	PUNCT
bracis-19059	71	19	we	we	PRON
bracis-19059	71	20	are	be	AUX
bracis-19059	71	21	applying	apply	VERB
bracis-19059	71	22	supervised	supervised	ADJ
bracis-19059	71	23	ml	ml	NOUN
bracis-19059	71	24	.	.	PUNCT
bracis-19059	72	1	this	this	DET
bracis-19059	72	2	target	target	NOUN
bracis-19059	72	3	is	be	AUX
bracis-19059	72	4	discretized	discretize	VERB
bracis-19059	72	5	between	between	ADP
bracis-19059	72	6	stabilizing	stabilize	VERB
bracis-19059	72	7	or	or	CCONJ
bracis-19059	72	8	destabilizing	destabilizing	ADJ
bracis-19059	72	9	(	(	PUNCT
bracis-19059	72	10	sect	sect	NOUN
bracis-19059	72	11	.	.	PUNCT
bracis-19059	72	12	 	 	SPACE
bracis-19059	72	13	2.2	2.2	NUM
bracis-19059	72	14	)	)	PUNCT
bracis-19059	72	15	.	.	PUNCT
bracis-19059	73	1	in	in	ADP
bracis-19059	73	2	this	this	DET
bracis-19059	73	3	way	way	NOUN
bracis-19059	73	4	,	,	PUNCT
bracis-19059	73	5	we	we	PRON
bracis-19059	73	6	are	be	AUX
bracis-19059	73	7	applying	apply	VERB
bracis-19059	73	8	as	as	ADP
bracis-19059	73	9	meta	meta	ADJ
bracis-19059	73	10	-	-	PUNCT
bracis-19059	73	11	classifiers	classifier	NOUN
bracis-19059	73	12	in	in	ADP
bracis-19059	73	13	ensemble	ensemble	ADJ
bracis-19059	73	14	learning	learning	NOUN
bracis-19059	73	15	tasks	task	NOUN
bracis-19059	73	16	the	the	DET
bracis-19059	73	17	classification	classification	NOUN
bracis-19059	73	18	algorithms	algorithm	NOUN
bracis-19059	73	19	decision	decision	NOUN
bracis-19059	73	20	trees	tree	NOUN
bracis-19059	73	21	(	(	PUNCT
bracis-19059	73	22	dt	dt	PROPN
bracis-19059	73	23	)	)	PUNCT
bracis-19059	73	24	,	,	PUNCT
bracis-19059	73	25	multilayer	multilayer	PROPN
bracis-19059	73	26	perceptron	perceptron	PROPN
bracis-19059	73	27	(	(	PUNCT
bracis-19059	73	28	mlp	mlp	PROPN
bracis-19059	73	29	)	)	PUNCT
bracis-19059	73	30	,	,	PUNCT
bracis-19059	73	31	naive	naive	ADJ
bracis-19059	73	32	bayes	bayes	NOUN
bracis-19059	73	33	(	(	PUNCT
bracis-19059	73	34	nb	nb	NOUN
bracis-19059	73	35	)	)	PUNCT
bracis-19059	73	36	and	and	CCONJ
bracis-19059	73	37	support	support	VERB
bracis-19059	73	38	vector	vector	NOUN
bracis-19059	73	39	machines	machine	NOUN
bracis-19059	73	40	(	(	PUNCT
bracis-19059	73	41	svm	svm	PROPN
bracis-19059	73	42	)	)	PUNCT
bracis-19059	73	43	.	.	PUNCT
bracis-19059	74	1	2.4	2.4	NUM
bracis-19059	74	2	ensemble	ensemble	ADJ
bracis-19059	74	3	learning	learning	NOUN
bracis-19059	74	4	ensemble	ensemble	ADJ
bracis-19059	74	5	learning	learning	NOUN
bracis-19059	74	6	is	be	AUX
bracis-19059	74	7	a	a	DET
bracis-19059	74	8	popular	popular	ADJ
bracis-19059	74	9	method	method	NOUN
bracis-19059	74	10	that	that	PRON
bracis-19059	74	11	combines	combine	VERB
bracis-19059	74	12	multiple	multiple	ADJ
bracis-19059	74	13	algorithms	algorithm	NOUN
bracis-19059	74	14	to	to	PART
bracis-19059	74	15	make	make	VERB
bracis-19059	74	16	a	a	DET
bracis-19059	74	17	decision	decision	NOUN
bracis-19059	74	18	usually	usually	ADV
bracis-19059	74	19	in	in	ADP
bracis-19059	74	20	supervised	supervised	ADJ
bracis-19059	74	21	ml	ml	NOUN
bracis-19059	75	1	[	[	X
bracis-19059	75	2	8	8	NUM
bracis-19059	75	3	]	]	PUNCT
bracis-19059	75	4	.	.	PUNCT
bracis-19059	76	1	ensembles	ensemble	NOUN
bracis-19059	76	2	have	have	AUX
bracis-19059	76	3	been	be	AUX
bracis-19059	76	4	applied	apply	VERB
bracis-19059	76	5	in	in	ADP
bracis-19059	76	6	several	several	ADJ
bracis-19059	76	7	research	research	NOUN
bracis-19059	76	8	areas	area	NOUN
bracis-19059	76	9	as	as	ADP
bracis-19059	76	10	economy	economy	NOUN
bracis-19059	76	11	,	,	PUNCT
bracis-19059	76	12	logistic	logistic	ADJ
bracis-19059	76	13	,	,	PUNCT
bracis-19059	76	14	medicine	medicine	NOUN
bracis-19059	76	15	,	,	PUNCT
bracis-19059	76	16	education	education	NOUN
bracis-19059	76	17	and	and	CCONJ
bracis-19059	76	18	so	so	ADV
bracis-19059	76	19	on	on	ADV
bracis-19059	76	20	.	.	PUNCT
bracis-19059	77	1	in	in	ADP
bracis-19059	77	2	bioinformatics	bioinformatics	NOUN
bracis-19059	77	3	,	,	PUNCT
bracis-19059	77	4	it	it	PRON
bracis-19059	77	5	has	have	AUX
bracis-19059	77	6	been	be	AUX
bracis-19059	77	7	applied	apply	VERB
bracis-19059	77	8	in	in	ADP
bracis-19059	77	9	different	different	ADJ
bracis-19059	77	10	contexts	context	NOUN
bracis-19059	77	11	as	as	SCONJ
bracis-19059	77	12	reviewed	review	VERB
bracis-19059	77	13	by	by	ADP
bracis-19059	77	14	yang	yang	PROPN
bracis-19059	78	1	[	[	X
bracis-19059	78	2	26	26	NUM
bracis-19059	78	3	]	]	PUNCT
bracis-19059	78	4	.	.	PUNCT
bracis-19059	79	1	in	in	ADP
bracis-19059	79	2	eickhotl	eickhotl	PROPN
bracis-19059	79	3	&	&	CCONJ
bracis-19059	79	4	cheng	cheng	PROPN
bracis-19059	79	5	[	[	X
bracis-19059	79	6	9	9	NUM
bracis-19059	79	7	]	]	PUNCT
bracis-19059	79	8	,	,	PUNCT
bracis-19059	79	9	the	the	DET
bracis-19059	79	10	authors	author	NOUN
bracis-19059	79	11	proposed	propose	VERB
bracis-19059	79	12	to	to	PART
bracis-19059	79	13	apply	apply	VERB
bracis-19059	79	14	boosting	boost	VERB
bracis-19059	79	15	ensembles	ensemble	NOUN
bracis-19059	79	16	of	of	ADP
bracis-19059	79	17	deep	deep	ADJ
bracis-19059	79	18	networks	network	NOUN
bracis-19059	79	19	for	for	ADP
bracis-19059	79	20	a	a	DET
bracis-19059	79	21	sequence	sequence	NOUN
bracis-19059	79	22	based	base	VERB
bracis-19059	79	23	prediction	prediction	NOUN
bracis-19059	79	24	of	of	ADP
bracis-19059	79	25	protein	protein	NOUN
bracis-19059	79	26	disorder	disorder	NOUN
bracis-19059	79	27	.	.	PUNCT
bracis-19059	80	1	mendonza	mendonza	PROPN
bracis-19059	80	2	et	et	PROPN
bracis-19059	80	3	al	al	PROPN
bracis-19059	80	4	.	.	PUNCT
bracis-19059	81	1	[	[	X
bracis-19059	81	2	15	15	NUM
bracis-19059	81	3	]	]	PUNCT
bracis-19059	81	4	discuss	discuss	VERB
bracis-19059	81	5	the	the	DET
bracis-19059	81	6	use	use	NOUN
bracis-19059	81	7	of	of	ADP
bracis-19059	81	8	ensemble	ensemble	ADJ
bracis-19059	81	9	-	-	PUNCT
bracis-19059	81	10	based	base	VERB
bracis-19059	81	11	solutions	solution	NOUN
bracis-19059	81	12	for	for	ADP
bracis-19059	81	13	inference	inference	NOUN
bracis-19059	81	14	of	of	ADP
bracis-19059	81	15	gene	gene	NOUN
bracis-19059	81	16	regulatory	regulatory	ADJ
bracis-19059	81	17	networks	network	NOUN
bracis-19059	81	18	and	and	CCONJ
bracis-19059	81	19	prediction	prediction	NOUN
bracis-19059	81	20	of	of	ADP
bracis-19059	81	21	micrornas	microrna	NOUN
bracis-19059	81	22	targets	target	NOUN
bracis-19059	81	23	.	.	PUNCT
bracis-19059	82	1	saha	saha	PROPN
bracis-19059	82	2	et	et	PROPN
bracis-19059	82	3	al	al	PROPN
bracis-19059	82	4	.	.	PUNCT
bracis-19059	83	1	[	[	X
bracis-19059	83	2	20	20	NUM
bracis-19059	83	3	]	]	PUNCT
bracis-19059	83	4	applied	apply	VERB
bracis-19059	83	5	an	an	DET
bracis-19059	83	6	ensemble	ensemble	ADJ
bracis-19059	83	7	learning	learning	NOUN
bracis-19059	83	8	method	method	NOUN
bracis-19059	83	9	on	on	ADP
bracis-19059	83	10	majority	majority	NOUN
bracis-19059	83	11	voting	vote	VERB
bracis-19059	83	12	on	on	ADP
bracis-19059	83	13	datasets	dataset	NOUN
bracis-19059	83	14	of	of	ADP
bracis-19059	83	15	protein	protein	NOUN
bracis-19059	83	16	-	-	PUNCT
bracis-19059	83	17	protein	protein	NOUN
bracis-19059	83	18	interactions	interaction	NOUN
bracis-19059	83	19	data	datum	NOUN
bracis-19059	83	20	.	.	PUNCT
bracis-19059	84	1	the	the	DET
bracis-19059	84	2	main	main	ADJ
bracis-19059	84	3	premise	premise	NOUN
bracis-19059	84	4	of	of	ADP
bracis-19059	84	5	this	this	DET
bracis-19059	84	6	method	method	NOUN
bracis-19059	84	7	is	be	AUX
bracis-19059	84	8	that	that	SCONJ
bracis-19059	84	9	by	by	ADP
bracis-19059	84	10	combining	combine	VERB
bracis-19059	84	11	multiple	multiple	ADJ
bracis-19059	84	12	models	model	NOUN
bracis-19059	84	13	,	,	PUNCT
bracis-19059	84	14	the	the	DET
bracis-19059	84	15	errors	error	NOUN
bracis-19059	84	16	of	of	ADP
bracis-19059	84	17	a	a	DET
bracis-19059	84	18	single	single	ADJ
bracis-19059	84	19	predictor	predictor	NOUN
bracis-19059	84	20	can	can	AUX
bracis-19059	84	21	be	be	AUX
bracis-19059	84	22	compensated	compensate	VERB
bracis-19059	84	23	by	by	ADP
bracis-19059	84	24	others	other	NOUN
bracis-19059	84	25	[	[	X
bracis-19059	84	26	8	8	NUM
bracis-19059	84	27	]	]	PUNCT
bracis-19059	84	28	.	.	PUNCT
bracis-19059	85	1	moreover	moreover	ADV
bracis-19059	85	2	,	,	PUNCT
bracis-19059	85	3	the	the	DET
bracis-19059	85	4	objective	objective	NOUN
bracis-19059	85	5	of	of	ADP
bracis-19059	85	6	ensemble	ensemble	ADJ
bracis-19059	85	7	methods	method	NOUN
bracis-19059	85	8	is	be	AUX
bracis-19059	85	9	not	not	PART
bracis-19059	85	10	only	only	ADV
bracis-19059	85	11	to	to	PART
bracis-19059	85	12	improve	improve	VERB
bracis-19059	85	13	the	the	DET
bracis-19059	85	14	predictions	prediction	NOUN
bracis-19059	85	15	but	but	CCONJ
bracis-19059	85	16	also	also	ADV
bracis-19059	85	17	to	to	PART
bracis-19059	85	18	enhance	enhance	VERB
bracis-19059	85	19	their	their	PRON
bracis-19059	85	20	capability	capability	NOUN
bracis-19059	85	21	of	of	ADP
bracis-19059	85	22	generalization	generalization	NOUN
bracis-19059	85	23	.	.	PUNCT
bracis-19059	86	1	an	an	DET
bracis-19059	86	2	ensemble	ensemble	ADJ
bracis-19059	86	3	method	method	NOUN
bracis-19059	86	4	for	for	ADP
bracis-19059	86	5	classification	classification	NOUN
bracis-19059	86	6	consists	consist	VERB
bracis-19059	86	7	in	in	ADP
bracis-19059	86	8	a	a	DET
bracis-19059	86	9	set	set	NOUN
bracis-19059	86	10	of	of	ADP
bracis-19059	86	11	k	k	PROPN
bracis-19059	86	12	models	model	NOUN
bracis-19059	86	13	,	,	PUNCT
bracis-19059	86	14	\(m_{1}\	\(m_{1}\	NUM
bracis-19059	86	15	)	)	PUNCT
bracis-19059	86	16	,	,	PUNCT
bracis-19059	86	17	\(m_{2},\ldots	\(m_{2},\ldots	PROPN
bracis-19059	86	18	,	,	PUNCT
bracis-19059	86	19	m_{k}\	m_{k}\	PROPN
bracis-19059	86	20	)	)	PUNCT
bracis-19059	86	21	,	,	PUNCT
bracis-19059	86	22	used	use	VERB
bracis-19059	86	23	to	to	PART
bracis-19059	86	24	build	build	VERB
bracis-19059	86	25	an	an	DET
bracis-19059	86	26	improved	improved	ADJ
bracis-19059	86	27	predictive	predictive	ADJ
bracis-19059	86	28	model	model	NOUN
bracis-19059	86	29	.	.	PUNCT
bracis-19059	87	1	a	a	DET
bracis-19059	87	2	dataset	dataset	NOUN
bracis-19059	87	3	d	d	NOUN
bracis-19059	87	4	is	be	AUX
bracis-19059	87	5	used	use	VERB
bracis-19059	87	6	to	to	PART
bracis-19059	87	7	obtain	obtain	VERB
bracis-19059	87	8	k	k	NOUN
bracis-19059	87	9	,	,	PUNCT
bracis-19059	87	10	\(d_{1}\	\(d_{1}\	NOUN
bracis-19059	87	11	)	)	PUNCT
bracis-19059	87	12	,	,	PUNCT
bracis-19059	87	13	\(d_{2},\ldots	\(d_{2},\ldots	PROPN
bracis-19059	87	14	,	,	PUNCT
bracis-19059	87	15	d_{k}\	d_{k}\	PROPN
bracis-19059	87	16	)	)	PUNCT
bracis-19059	87	17	datasets	dataset	NOUN
bracis-19059	87	18	in	in	ADP
bracis-19059	87	19	which	which	PRON
bracis-19059	87	20	\(d_{i}\	\(d_{i}\	VERB
bracis-19059	87	21	)	)	PUNCT
bracis-19059	87	22	(	(	PUNCT
bracis-19059	87	23	1	1	NUM
bracis-19059	87	24	\(\le	\(\le	PROPN
bracis-19059	87	25	\	\	NOUN
bracis-19059	87	26	)	)	PUNCT
bracis-19059	87	27	i	i	PRON
bracis-19059	87	28	\(\le	\(\le	PROPN
bracis-19059	87	29	\	\	ADJ
bracis-19059	87	30	)	)	PUNCT
bracis-19059	87	31	k-1	k-1	PROPN
bracis-19059	87	32	)	)	PUNCT
bracis-19059	87	33	is	be	AUX
bracis-19059	87	34	used	use	VERB
bracis-19059	87	35	to	to	PART
bracis-19059	87	36	build	build	VERB
bracis-19059	87	37	the	the	DET
bracis-19059	87	38	classification	classification	NOUN
bracis-19059	87	39	model	model	NOUN
bracis-19059	87	40	\(m_{i}\	\(m_{i}\	PROPN
bracis-19059	87	41	)	)	PUNCT
bracis-19059	88	1	[	[	X
bracis-19059	88	2	13	13	NUM
bracis-19059	88	3	]	]	PUNCT
bracis-19059	88	4	.	.	PUNCT
bracis-19059	89	1	there	there	PRON
bracis-19059	89	2	are	be	VERB
bracis-19059	89	3	several	several	ADJ
bracis-19059	89	4	methodologies	methodology	NOUN
bracis-19059	89	5	for	for	ADP
bracis-19059	89	6	forming	form	VERB
bracis-19059	89	7	an	an	DET
bracis-19059	89	8	ensemble	ensemble	ADJ
bracis-19059	89	9	considering	consider	VERB
bracis-19059	89	10	the	the	DET
bracis-19059	89	11	k	k	PROPN
bracis-19059	89	12	induced	induce	VERB
bracis-19059	89	13	models	model	NOUN
bracis-19059	89	14	:	:	PUNCT
bracis-19059	89	15	modifying	modify	VERB
bracis-19059	89	16	the	the	DET
bracis-19059	89	17	\(d_{1}\	\(d_{1}\	NOUN
bracis-19059	89	18	)	)	PUNCT
bracis-19059	89	19	,	,	PUNCT
bracis-19059	89	20	\(d_{2},\ldots	\(d_{2},\ldots	PROPN
bracis-19059	89	21	,	,	PUNCT
bracis-19059	89	22	d_{k}\	d_{k}\	PROPN
bracis-19059	89	23	)	)	PUNCT
bracis-19059	89	24	datasets	dataset	NOUN
bracis-19059	89	25	(	(	PUNCT
bracis-19059	89	26	sub	sub	ADJ
bracis-19059	89	27	-	-	ADJ
bracis-19059	89	28	sampling	sample	VERB
bracis-19059	89	29	,	,	PUNCT
bracis-19059	89	30	bagging	bagging	NOUN
bracis-19059	89	31	,	,	PUNCT
bracis-19059	89	32	randomly	randomly	ADV
bracis-19059	89	33	sampling	sample	VERB
bracis-19059	89	34	,	,	PUNCT
bracis-19059	89	35	etc	etc	X
bracis-19059	89	36	.	.	X
bracis-19059	89	37	)	)	PUNCT
bracis-19059	89	38	,	,	PUNCT
bracis-19059	89	39	modifying	modify	VERB
bracis-19059	89	40	the	the	DET
bracis-19059	89	41	learning	learning	NOUN
bracis-19059	89	42	task	task	NOUN
bracis-19059	89	43	,	,	PUNCT
bracis-19059	89	44	exploiting	exploit	VERB
bracis-19059	89	45	the	the	DET
bracis-19059	89	46	predictive	predictive	ADJ
bracis-19059	89	47	algorithms	algorithms	NOUN
bracis-19059	89	48	characteristics	characteristic	NOUN
bracis-19059	89	49	and	and	CCONJ
bracis-19059	89	50	so	so	ADV
bracis-19059	89	51	on	on	ADV
bracis-19059	89	52	.	.	PUNCT
bracis-19059	90	1	thus	thus	ADV
bracis-19059	90	2	,	,	PUNCT
bracis-19059	90	3	given	give	VERB
bracis-19059	90	4	a	a	DET
bracis-19059	90	5	new	new	ADJ
bracis-19059	90	6	instance	instance	NOUN
bracis-19059	90	7	to	to	PART
bracis-19059	90	8	classify	classify	VERB
bracis-19059	90	9	,	,	PUNCT
bracis-19059	90	10	each	each	DET
bracis-19059	90	11	one	one	NUM
bracis-19059	90	12	of	of	ADP
bracis-19059	90	13	the	the	DET
bracis-19059	90	14	induced	induced	ADJ
bracis-19059	90	15	models	model	NOUN
bracis-19059	90	16	contributes	contribute	VERB
bracis-19059	90	17	to	to	PART
bracis-19059	90	18	compose	compose	VERB
bracis-19059	90	19	the	the	DET
bracis-19059	90	20	final	final	ADJ
bracis-19059	90	21	decision	decision	NOUN
bracis-19059	90	22	of	of	ADP
bracis-19059	90	23	the	the	DET
bracis-19059	90	24	ensemble	ensemble	NOUN
bracis-19059	90	25	.	.	PUNCT
bracis-19059	91	1	combining	combine	VERB
bracis-19059	91	2	the	the	DET
bracis-19059	91	3	predictive	predictive	ADJ
bracis-19059	91	4	models	model	NOUN
bracis-19059	91	5	can	can	AUX
bracis-19059	91	6	reduce	reduce	VERB
bracis-19059	91	7	the	the	DET
bracis-19059	91	8	risk	risk	NOUN
bracis-19059	91	9	to	to	PART
bracis-19059	91	10	choose	choose	VERB
bracis-19059	91	11	a	a	DET
bracis-19059	91	12	bad	bad	ADJ
bracis-19059	91	13	result	result	NOUN
bracis-19059	91	14	since	since	SCONJ
bracis-19059	91	15	the	the	DET
bracis-19059	91	16	result	result	NOUN
bracis-19059	91	17	of	of	ADP
bracis-19059	91	18	the	the	DET
bracis-19059	91	19	combination	combination	NOUN
bracis-19059	91	20	usually	usually	ADV
bracis-19059	91	21	is	be	AUX
bracis-19059	91	22	better	well	ADJ
bracis-19059	91	23	than	than	ADP
bracis-19059	91	24	the	the	DET
bracis-19059	91	25	best	well	ADV
bracis-19059	91	26	induced	induced	ADJ
bracis-19059	91	27	model	model	NOUN
bracis-19059	91	28	.	.	PUNCT
bracis-19059	92	1	the	the	DET
bracis-19059	92	2	definition	definition	NOUN
bracis-19059	92	3	of	of	ADP
bracis-19059	92	4	the	the	DET
bracis-19059	92	5	best	good	ADJ
bracis-19059	92	6	combination	combination	NOUN
bracis-19059	92	7	of	of	ADP
bracis-19059	92	8	classifiers	classifier	NOUN
bracis-19059	92	9	is	be	AUX
bracis-19059	92	10	a	a	DET
bracis-19059	92	11	combinatorial	combinatorial	ADJ
bracis-19059	92	12	problem	problem	NOUN
bracis-19059	92	13	and	and	CCONJ
bracis-19059	92	14	there	there	PRON
bracis-19059	92	15	are	be	VERB
bracis-19059	92	16	different	different	ADJ
bracis-19059	92	17	implementations	implementation	NOUN
bracis-19059	92	18	of	of	ADP
bracis-19059	92	19	ensemble	ensemble	ADJ
bracis-19059	92	20	methods	method	NOUN
bracis-19059	92	21	.	.	PUNCT
bracis-19059	93	1	in	in	ADP
bracis-19059	93	2	this	this	DET
bracis-19059	93	3	paper	paper	NOUN
bracis-19059	93	4	we	we	PRON
bracis-19059	93	5	propose	propose	VERB
bracis-19059	93	6	to	to	PART
bracis-19059	93	7	generate	generate	VERB
bracis-19059	93	8	stacking	stack	VERB
bracis-19059	93	9	[	[	X
bracis-19059	93	10	16	16	NUM
bracis-19059	93	11	]	]	PUNCT
bracis-19059	93	12	,	,	PUNCT
bracis-19059	93	13	bagging	bag	VERB
bracis-19059	93	14	[	[	X
bracis-19059	93	15	3	3	NUM
bracis-19059	93	16	]	]	PUNCT
bracis-19059	93	17	and	and	CCONJ
bracis-19059	93	18	boosting	boost	VERB
bracis-19059	93	19	[	[	PUNCT
bracis-19059	93	20	11	11	NUM
bracis-19059	93	21	]	]	X
bracis-19059	93	22	ensemble	ensemble	ADJ
bracis-19059	93	23	models	model	NOUN
bracis-19059	93	24	combining	combine	VERB
bracis-19059	93	25	different	different	ADJ
bracis-19059	93	26	classification	classification	NOUN
bracis-19059	93	27	algorithms	algorithm	NOUN
bracis-19059	93	28	.	.	PUNCT
bracis-19059	94	1	stacking	stack	VERB
bracis-19059	94	2	[	[	X
bracis-19059	94	3	16	16	NUM
bracis-19059	94	4	]	]	PUNCT
bracis-19059	94	5	is	be	AUX
bracis-19059	94	6	a	a	DET
bracis-19059	94	7	heterogeneous	heterogeneous	ADJ
bracis-19059	94	8	ensemble	ensemble	ADJ
bracis-19059	94	9	method	method	NOUN
bracis-19059	94	10	where	where	SCONJ
bracis-19059	94	11	the	the	DET
bracis-19059	94	12	models	model	NOUN
bracis-19059	94	13	are	be	AUX
bracis-19059	94	14	obtained	obtain	VERB
bracis-19059	94	15	considering	consider	VERB
bracis-19059	94	16	different	different	ADJ
bracis-19059	94	17	algorithms	algorithm	NOUN
bracis-19059	94	18	and	and	CCONJ
bracis-19059	94	19	one	one	NUM
bracis-19059	94	20	unique	unique	ADJ
bracis-19059	94	21	dataset	dataset	NOUN
bracis-19059	94	22	.	.	PUNCT
bracis-19059	95	1	then	then	ADV
bracis-19059	95	2	the	the	DET
bracis-19059	95	3	answers	answer	NOUN
bracis-19059	95	4	of	of	ADP
bracis-19059	95	5	the	the	DET
bracis-19059	95	6	predictive	predictive	ADJ
bracis-19059	95	7	models	model	NOUN
bracis-19059	95	8	are	be	AUX
bracis-19059	95	9	combined	combine	VERB
bracis-19059	95	10	in	in	ADP
bracis-19059	95	11	a	a	DET
bracis-19059	95	12	new	new	ADJ
bracis-19059	95	13	dataset	dataset	NOUN
bracis-19059	95	14	[	[	X
bracis-19059	95	15	31	31	NUM
bracis-19059	95	16	]	]	PUNCT
bracis-19059	95	17	and	and	CCONJ
bracis-19059	95	18	a	a	DET
bracis-19059	95	19	meta	meta	ADJ
bracis-19059	95	20	-	-	PUNCT
bracis-19059	95	21	classifier	classifier	NOUN
bracis-19059	95	22	is	be	AUX
bracis-19059	95	23	introduced	introduce	VERB
bracis-19059	95	24	.	.	PUNCT
bracis-19059	96	1	bagging	bagging	NOUN
bracis-19059	96	2	and	and	CCONJ
bracis-19059	96	3	boosting	boost	VERB
bracis-19059	96	4	are	be	AUX
bracis-19059	96	5	homogeneous	homogeneous	ADJ
bracis-19059	96	6	ensemble	ensemble	ADJ
bracis-19059	96	7	methods	method	NOUN
bracis-19059	96	8	.	.	PUNCT
bracis-19059	97	1	in	in	ADP
bracis-19059	97	2	bagging	bag	VERB
bracis-19059	97	3	[	[	X
bracis-19059	97	4	3	3	NUM
bracis-19059	97	5	]	]	PUNCT
bracis-19059	97	6	,	,	PUNCT
bracis-19059	97	7	the	the	DET
bracis-19059	97	8	individual	individual	ADJ
bracis-19059	97	9	models	model	NOUN
bracis-19059	97	10	are	be	AUX
bracis-19059	97	11	built	build	VERB
bracis-19059	97	12	parallel	parallel	ADJ
bracis-19059	97	13	,	,	PUNCT
bracis-19059	97	14	are	be	AUX
bracis-19059	97	15	different	different	ADJ
bracis-19059	97	16	from	from	ADP
bracis-19059	97	17	each	each	DET
bracis-19059	97	18	other	other	ADJ
bracis-19059	97	19	and	and	CCONJ
bracis-19059	97	20	all	all	DET
bracis-19059	97	21	the	the	DET
bracis-19059	97	22	instances	instance	NOUN
bracis-19059	97	23	have	have	VERB
bracis-19059	97	24	the	the	DET
bracis-19059	97	25	same	same	ADJ
bracis-19059	97	26	weight	weight	NOUN
bracis-19059	97	27	.	.	PUNCT
bracis-19059	98	1	in	in	ADP
bracis-19059	98	2	boosting	boost	VERB
bracis-19059	98	3	[	[	PUNCT
bracis-19059	98	4	11	11	NUM
bracis-19059	98	5	]	]	X
bracis-19059	98	6	individual	individual	ADJ
bracis-19059	98	7	models	model	NOUN
bracis-19059	98	8	are	be	AUX
bracis-19059	98	9	built	build	VERB
bracis-19059	98	10	sequentially	sequentially	ADV
bracis-19059	98	11	where	where	SCONJ
bracis-19059	98	12	the	the	DET
bracis-19059	98	13	outputs	output	NOUN
bracis-19059	98	14	of	of	ADP
bracis-19059	98	15	the	the	DET
bracis-19059	98	16	first	first	ADJ
bracis-19059	98	17	model	model	NOUN
bracis-19059	98	18	is	be	AUX
bracis-19059	98	19	used	use	VERB
bracis-19059	98	20	on	on	ADP
bracis-19059	98	21	the	the	DET
bracis-19059	98	22	next	next	ADJ
bracis-19059	98	23	and	and	CCONJ
bracis-19059	98	24	so	so	ADV
bracis-19059	98	25	on	on	ADV
bracis-19059	98	26	.	.	PUNCT
bracis-19059	99	1	so	so	ADV
bracis-19059	99	2	,	,	PUNCT
bracis-19059	99	3	during	during	ADP
bracis-19059	99	4	training	training	NOUN
bracis-19059	99	5	,	,	PUNCT
bracis-19059	99	6	the	the	DET
bracis-19059	99	7	algorithm	algorithm	NOUN
bracis-19059	99	8	defines	define	VERB
bracis-19059	99	9	weights	weight	NOUN
bracis-19059	99	10	for	for	ADP
bracis-19059	99	11	the	the	DET
bracis-19059	99	12	instances	instance	NOUN
bracis-19059	99	13	and	and	CCONJ
bracis-19059	99	14	the	the	DET
bracis-19059	99	15	ensemble	ensemble	ADJ
bracis-19059	99	16	models	model	NOUN
bracis-19059	99	17	are	be	AUX
bracis-19059	99	18	incrementally	incrementally	ADV
bracis-19059	99	19	built	build	VERB
bracis-19059	99	20	.	.	PUNCT
bracis-19059	100	1	3	3	NUM
bracis-19059	100	2	individual	individual	ADJ
bracis-19059	100	3	tools	tool	NOUN
bracis-19059	100	4	for	for	ADP
bracis-19059	100	5	 	 	SPACE
bracis-19059	100	6	predicting	predict	VERB
bracis-19059	100	7	the	the	DET
bracis-19059	100	8	 	 	SPACE
bracis-19059	100	9	effects	effect	NOUN
bracis-19059	100	10	of	of	ADP
bracis-19059	100	11	 	 	SPACE
bracis-19059	100	12	point	point	NOUN
bracis-19059	100	13	mutations	mutation	NOUN
bracis-19059	100	14	in	in	ADP
bracis-19059	100	15	 	 	SPACE
bracis-19059	100	16	protein	protein	NOUN
bracis-19059	100	17	stability	stability	NOUN
bracis-19059	100	18	there	there	PRON
bracis-19059	100	19	are	be	VERB
bracis-19059	100	20	many	many	ADJ
bracis-19059	100	21	tools	tool	NOUN
bracis-19059	100	22	for	for	ADP
bracis-19059	100	23	predicting	predict	VERB
bracis-19059	100	24	the	the	DET
bracis-19059	100	25	effects	effect	NOUN
bracis-19059	100	26	of	of	ADP
bracis-19059	100	27	point	point	NOUN
bracis-19059	100	28	mutations	mutation	NOUN
bracis-19059	100	29	in	in	ADP
bracis-19059	100	30	protein	protein	NOUN
bracis-19059	100	31	stability	stability	NOUN
bracis-19059	100	32	.	.	PUNCT
bracis-19059	101	1	in	in	ADP
bracis-19059	101	2	this	this	DET
bracis-19059	101	3	work	work	NOUN
bracis-19059	101	4	we	we	PRON
bracis-19059	101	5	have	have	AUX
bracis-19059	101	6	chosen	choose	VERB
bracis-19059	101	7	the	the	DET
bracis-19059	101	8	tools	tool	NOUN
bracis-19059	101	9	based	base	VERB
bracis-19059	101	10	on	on	ADP
bracis-19059	101	11	the	the	DET
bracis-19059	101	12	following	follow	VERB
bracis-19059	101	13	characteristics	characteristic	NOUN
bracis-19059	101	14	:	:	PUNCT
bracis-19059	101	15	they	they	PRON
bracis-19059	101	16	produce	produce	VERB
bracis-19059	101	17	a	a	DET
bracis-19059	101	18	numerical	numerical	ADJ
bracis-19059	101	19	prediction	prediction	NOUN
bracis-19059	101	20	of	of	ADP
bracis-19059	101	21	\(\vardelta	\(\vardelta	NOUN
bracis-19059	101	22	\vardelta	\vardelta	X
bracis-19059	101	23	g\	g\	PROPN
bracis-19059	101	24	)	)	PUNCT
bracis-19059	101	25	;	;	PUNCT
bracis-19059	101	26	their	their	PRON
bracis-19059	101	27	response	response	NOUN
bracis-19059	101	28	time	time	NOUN
bracis-19059	101	29	should	should	AUX
bracis-19059	101	30	be	be	AUX
bracis-19059	101	31	short	short	ADJ
bracis-19059	101	32	;	;	PUNCT
bracis-19059	101	33	they	they	PRON
bracis-19059	101	34	consider	consider	VERB
bracis-19059	101	35	protein	protein	NOUN
bracis-19059	101	36	structure	structure	NOUN
bracis-19059	101	37	as	as	ADP
bracis-19059	101	38	input	input	NOUN
bracis-19059	101	39	;	;	PUNCT
bracis-19059	101	40	they	they	PRON
bracis-19059	101	41	permit	permit	VERB
bracis-19059	101	42	automatic	automatic	ADJ
bracis-19059	101	43	submission	submission	NOUN
bracis-19059	101	44	and	and	CCONJ
bracis-19059	101	45	license	license	NOUN
bracis-19059	101	46	of	of	ADP
bracis-19059	101	47	use	use	NOUN
bracis-19059	101	48	for	for	ADP
bracis-19059	101	49	academic	academic	ADJ
bracis-19059	101	50	purposes	purpose	NOUN
bracis-19059	101	51	is	be	AUX
bracis-19059	101	52	available	available	ADJ
bracis-19059	101	53	.	.	PUNCT
bracis-19059	102	1	in	in	ADP
bracis-19059	102	2	doing	do	VERB
bracis-19059	102	3	so	so	ADV
bracis-19059	102	4	,	,	PUNCT
bracis-19059	102	5	the	the	DET
bracis-19059	102	6	selected	select	VERB
bracis-19059	102	7	tools	tool	NOUN
bracis-19059	102	8	are	be	AUX
bracis-19059	102	9	:	:	PUNCT
bracis-19059	102	10	cupsat	cupsat	VERB
bracis-19059	102	11	[	[	PUNCT
bracis-19059	102	12	17	17	NUM
bracis-19059	102	13	]	]	PUNCT
bracis-19059	102	14	,	,	PUNCT
bracis-19059	102	15	sdm	sdm	PROPN
bracis-19059	103	1	[	[	X
bracis-19059	103	2	25	25	NUM
bracis-19059	103	3	]	]	PUNCT
bracis-19059	103	4	,	,	PUNCT
bracis-19059	103	5	mcsm	mcsm	NOUN
bracis-19059	103	6	[	[	X
bracis-19059	103	7	18	18	NUM
bracis-19059	103	8	]	]	PUNCT
bracis-19059	103	9	,	,	PUNCT
bracis-19059	103	10	duet	duet	NOUN
bracis-19059	103	11	[	[	X
bracis-19059	103	12	19	19	NUM
bracis-19059	103	13	]	]	PUNCT
bracis-19059	103	14	,	,	PUNCT
bracis-19059	103	15	maestro	maestro	NOUN
bracis-19059	103	16	[	[	X
bracis-19059	103	17	14	14	NUM
bracis-19059	103	18	]	]	PUNCT
bracis-19059	103	19	and	and	CCONJ
bracis-19059	103	20	popmusic	popmusic	ADJ
bracis-19059	104	1	[	[	X
bracis-19059	104	2	7	7	NUM
bracis-19059	104	3	]	]	PUNCT
bracis-19059	104	4	.	.	PUNCT
bracis-19059	105	1	besides	besides	SCONJ
bracis-19059	105	2	,	,	PUNCT
bracis-19059	105	3	these	these	DET
bracis-19059	105	4	tools	tool	NOUN
bracis-19059	105	5	have	have	VERB
bracis-19059	105	6	similar	similar	ADJ
bracis-19059	105	7	input	input	NOUN
bracis-19059	105	8	forms	form	NOUN
bracis-19059	105	9	and	and	CCONJ
bracis-19059	105	10	therefore	therefore	ADV
bracis-19059	105	11	similar	similar	ADJ
bracis-19059	105	12	outputs	output	NOUN
bracis-19059	105	13	,	,	PUNCT
bracis-19059	105	14	which	which	PRON
bracis-19059	105	15	allow	allow	VERB
bracis-19059	105	16	us	we	PRON
bracis-19059	105	17	to	to	PART
bracis-19059	105	18	better	well	ADV
bracis-19059	105	19	manipulate	manipulate	VERB
bracis-19059	105	20	the	the	DET
bracis-19059	105	21	data	datum	NOUN
bracis-19059	105	22	.	.	PUNCT
bracis-19059	106	1	3.1	3.1	NUM
bracis-19059	106	2	cupsat	cupsat	VERB
bracis-19059	106	3	cupsat	cupsat	NOUN
bracis-19059	106	4	(	(	PUNCT
bracis-19059	106	5	cologne	cologne	NOUN
bracis-19059	106	6	university	university	NOUN
bracis-19059	106	7	protein	protein	NOUN
bracis-19059	106	8	stability	stability	NOUN
bracis-19059	106	9	analysis	analysis	NOUN
bracis-19059	106	10	tool	tool	NOUN
bracis-19059	106	11	)	)	PUNCT
bracis-19059	107	1	[	[	X
bracis-19059	107	2	17	17	NUM
bracis-19059	107	3	]	]	PUNCT
bracis-19059	107	4	is	be	AUX
bracis-19059	107	5	a	a	DET
bracis-19059	107	6	web	web	NOUN
bracis-19059	107	7	tool	tool	NOUN
bracis-19059	107	8	that	that	PRON
bracis-19059	107	9	analyzes	analyze	VERB
bracis-19059	107	10	and	and	CCONJ
bracis-19059	107	11	predicts	predict	VERB
bracis-19059	107	12	protein	protein	NOUN
bracis-19059	107	13	stability	stability	NOUN
bracis-19059	107	14	changes	change	VERB
bracis-19059	107	15	for	for	ADP
bracis-19059	107	16	point	point	NOUN
bracis-19059	107	17	mutations	mutation	NOUN
bracis-19059	107	18	.	.	PUNCT
bracis-19059	108	1	it	it	PRON
bracis-19059	108	2	uses	use	VERB
bracis-19059	108	3	the	the	DET
bracis-19059	108	4	specific	specific	ADJ
bracis-19059	108	5	structural	structural	ADJ
bracis-19059	108	6	environment	environment	NOUN
bracis-19059	108	7	of	of	ADP
bracis-19059	108	8	potential	potential	ADJ
bracis-19059	108	9	atoms	atom	NOUN
bracis-19059	108	10	and	and	CCONJ
bracis-19059	108	11	potential	potential	ADJ
bracis-19059	108	12	torsion	torsion	NOUN
bracis-19059	108	13	angles	angle	NOUN
bracis-19059	108	14	,	,	PUNCT
bracis-19059	108	15	in	in	ADP
bracis-19059	108	16	the	the	DET
bracis-19059	108	17	unwinding	unwinding	NOUN
bracis-19059	108	18	,	,	PUNCT
bracis-19059	108	19	to	to	PART
bracis-19059	108	20	predict	predict	VERB
bracis-19059	108	21	the	the	DET
bracis-19059	108	22	\(\vardelta	\(\vardelta	NOUN
bracis-19059	108	23	\vardelta	\vardelta	NOUN
bracis-19059	108	24	\)g	\)g	NOUN
bracis-19059	108	25	.	.	PUNCT
bracis-19059	109	1	their	their	PRON
bracis-19059	109	2	results	result	NOUN
bracis-19059	109	3	consist	consist	VERB
bracis-19059	109	4	of	of	ADP
bracis-19059	109	5	informing	inform	VERB
bracis-19059	109	6	the	the	DET
bracis-19059	109	7	structural	structural	ADJ
bracis-19059	109	8	characteristics	characteristic	NOUN
bracis-19059	109	9	about	about	ADP
bracis-19059	109	10	the	the	DET
bracis-19059	109	11	mutation	mutation	NOUN
bracis-19059	109	12	of	of	ADP
bracis-19059	109	13	this	this	DET
bracis-19059	109	14	location	location	NOUN
bracis-19059	109	15	,	,	PUNCT
bracis-19059	109	16	such	such	ADJ
bracis-19059	109	17	as	as	ADP
bracis-19059	109	18	:	:	PUNCT
bracis-19059	109	19	solvent	solvent	ADJ
bracis-19059	109	20	accessibility	accessibility	NOUN
bracis-19059	109	21	,	,	PUNCT
bracis-19059	109	22	secondary	secondary	ADJ
bracis-19059	109	23	structure	structure	NOUN
bracis-19059	109	24	and	and	CCONJ
bracis-19059	109	25	torsion	torsion	NOUN
bracis-19059	109	26	angles	angle	NOUN
bracis-19059	109	27	.	.	PUNCT
bracis-19059	110	1	it	it	PRON
bracis-19059	110	2	also	also	ADV
bracis-19059	110	3	looks	look	VERB
bracis-19059	110	4	at	at	ADP
bracis-19059	110	5	the	the	DET
bracis-19059	110	6	ability	ability	NOUN
bracis-19059	110	7	of	of	ADP
bracis-19059	110	8	mutated	mutate	VERB
bracis-19059	110	9	amino	amino	ADJ
bracis-19059	110	10	acids	acid	NOUN
bracis-19059	110	11	to	to	PART
bracis-19059	110	12	adapt	adapt	VERB
bracis-19059	110	13	to	to	PART
bracis-19059	110	14	twist	twist	VERB
bracis-19059	110	15	angles	angle	NOUN
bracis-19059	110	16	.	.	PUNCT
bracis-19059	111	1	it	it	PRON
bracis-19059	111	2	uses	use	VERB
bracis-19059	111	3	several	several	ADJ
bracis-19059	111	4	validation	validation	NOUN
bracis-19059	111	5	tests	test	NOUN
bracis-19059	111	6	(	(	PUNCT
bracis-19059	111	7	split	split	NOUN
bracis-19059	111	8	-	-	PUNCT
bracis-19059	111	9	sample	sample	NOUN
bracis-19059	111	10	,	,	PUNCT
bracis-19059	111	11	jack	jack	NOUN
bracis-19059	111	12	-	-	PUNCT
bracis-19059	111	13	knife	knife	NOUN
bracis-19059	111	14	and	and	CCONJ
bracis-19059	111	15	k	k	NOUN
bracis-19059	111	16	-	-	ADJ
bracis-19059	111	17	fold	fold	VERB
bracis-19059	111	18	)	)	PUNCT
bracis-19059	111	19	to	to	PART
bracis-19059	111	20	guarantee	guarantee	VERB
bracis-19059	111	21	the	the	DET
bracis-19059	111	22	reliability	reliability	NOUN
bracis-19059	111	23	,	,	PUNCT
bracis-19059	111	24	accuracy	accuracy	NOUN
bracis-19059	111	25	and	and	CCONJ
bracis-19059	111	26	transferability	transferability	NOUN
bracis-19059	111	27	of	of	ADP
bracis-19059	111	28	the	the	DET
bracis-19059	111	29	prediction	prediction	NOUN
bracis-19059	111	30	methods	method	NOUN
bracis-19059	111	31	,	,	PUNCT
bracis-19059	111	32	which	which	PRON
bracis-19059	111	33	guarantee	guarantee	VERB
bracis-19059	111	34	an	an	DET
bracis-19059	111	35	accuracy	accuracy	NOUN
bracis-19059	111	36	of	of	ADP
bracis-19059	111	37	more	more	ADJ
bracis-19059	111	38	than	than	ADP
bracis-19059	111	39	80	80	NUM
bracis-19059	111	40	%	%	NOUN
bracis-19059	111	41	on	on	ADP
bracis-19059	111	42	their	their	PRON
bracis-19059	111	43	tests	test	NOUN
bracis-19059	111	44	[	[	X
bracis-19059	111	45	17	17	NUM
bracis-19059	111	46	]	]	SYM
bracis-19059	111	47	.	.	PUNCT
bracis-19059	112	1	3.2	3.2	NUM
bracis-19059	112	2	sdm	sdm	NOUN
bracis-19059	112	3	site	site	NOUN
bracis-19059	112	4	directed	direct	VERB
bracis-19059	112	5	mutator	mutator	NOUN
bracis-19059	112	6	(	(	PUNCT
bracis-19059	112	7	sdm	sdm	PROPN
bracis-19059	112	8	)	)	PUNCT
bracis-19059	113	1	[	[	X
bracis-19059	113	2	25	25	NUM
bracis-19059	113	3	]	]	PUNCT
bracis-19059	113	4	web	web	NOUN
bracis-19059	113	5	tool	tool	NOUN
bracis-19059	113	6	is	be	AUX
bracis-19059	113	7	a	a	DET
bracis-19059	113	8	potential	potential	ADJ
bracis-19059	113	9	energy	energy	NOUN
bracis-19059	113	10	statistical	statistical	ADJ
bracis-19059	113	11	function	function	NOUN
bracis-19059	113	12	with	with	ADP
bracis-19059	113	13	the	the	DET
bracis-19059	113	14	aim	aim	NOUN
bracis-19059	113	15	of	of	ADP
bracis-19059	113	16	predicting	predict	VERB
bracis-19059	113	17	the	the	DET
bracis-19059	113	18	effect	effect	NOUN
bracis-19059	113	19	that	that	SCONJ
bracis-19059	113	20	single	single	ADJ
bracis-19059	113	21	nucleotide	nucleotide	ADJ
bracis-19059	113	22	polymorphisms	polymorphism	NOUN
bracis-19059	113	23	will	will	AUX
bracis-19059	113	24	have	have	VERB
bracis-19059	113	25	on	on	ADP
bracis-19059	113	26	protein	protein	NOUN
bracis-19059	113	27	stability	stability	NOUN
bracis-19059	113	28	.	.	PUNCT
bracis-19059	114	1	using	use	VERB
bracis-19059	114	2	amino	amino	NOUN
bracis-19059	114	3	acid	acid	NOUN
bracis-19059	114	4	substitution	substitution	NOUN
bracis-19059	114	5	frequencies	frequency	NOUN
bracis-19059	114	6	in	in	ADP
bracis-19059	114	7	specific	specific	ADJ
bracis-19059	114	8	environments	environment	NOUN
bracis-19059	114	9	within	within	ADP
bracis-19059	114	10	protein	protein	NOUN
bracis-19059	114	11	families	family	NOUN
bracis-19059	114	12	,	,	PUNCT
bracis-19059	114	13	the	the	DET
bracis-19059	114	14	tool	tool	NOUN
bracis-19059	114	15	calculates	calculate	VERB
bracis-19059	114	16	a	a	DET
bracis-19059	114	17	stability	stability	NOUN
bracis-19059	114	18	score	score	NOUN
bracis-19059	114	19	that	that	PRON
bracis-19059	114	20	is	be	AUX
bracis-19059	114	21	analogous	analogous	ADJ
bracis-19059	114	22	to	to	ADP
bracis-19059	114	23	the	the	DET
bracis-19059	114	24	variation	variation	NOUN
bracis-19059	114	25	in	in	ADP
bracis-19059	114	26	free	free	ADJ
bracis-19059	114	27	energy	energy	NOUN
bracis-19059	114	28	between	between	ADP
bracis-19059	114	29	the	the	DET
bracis-19059	114	30	native	native	ADJ
bracis-19059	114	31	and	and	CCONJ
bracis-19059	114	32	mutant	mutant	ADJ
bracis-19059	114	33	state	state	NOUN
bracis-19059	114	34	of	of	ADP
bracis-19059	114	35	the	the	DET
bracis-19059	114	36	protein	protein	NOUN
bracis-19059	114	37	.	.	PUNCT
bracis-19059	115	1	3.3	3.3	NUM
bracis-19059	115	2	mcsm	mcsm	NOUN
bracis-19059	115	3	mutation	mutation	NOUN
bracis-19059	115	4	cutoff	cutoff	NOUN
bracis-19059	115	5	scanning	scan	VERB
bracis-19059	115	6	matrix	matrix	NOUN
bracis-19059	115	7	(	(	PUNCT
bracis-19059	115	8	mcsm	mcsm	NOUN
bracis-19059	115	9	)	)	PUNCT
bracis-19059	115	10	,	,	PUNCT
bracis-19059	115	11	is	be	AUX
bracis-19059	115	12	a	a	DET
bracis-19059	115	13	predictor	predictor	NOUN
bracis-19059	115	14	that	that	PRON
bracis-19059	115	15	uses	use	VERB
bracis-19059	115	16	structural	structural	ADJ
bracis-19059	115	17	graph	graph	NOUN
bracis-19059	115	18	-	-	PUNCT
bracis-19059	115	19	based	base	VERB
bracis-19059	115	20	signatures	signature	NOUN
bracis-19059	115	21	of	of	ADP
bracis-19059	115	22	proteins	protein	NOUN
bracis-19059	115	23	to	to	PART
bracis-19059	115	24	study	study	VERB
bracis-19059	115	25	the	the	DET
bracis-19059	115	26	impact	impact	NOUN
bracis-19059	115	27	of	of	ADP
bracis-19059	115	28	mutations	mutation	NOUN
bracis-19059	115	29	[	[	X
bracis-19059	115	30	18	18	NUM
bracis-19059	115	31	]	]	PUNCT
bracis-19059	115	32	.	.	PUNCT
bracis-19059	116	1	mcsm	mcsm	NOUN
bracis-19059	116	2	signatures	signature	NOUN
bracis-19059	116	3	were	be	AUX
bracis-19059	116	4	derived	derive	VERB
bracis-19059	116	5	from	from	ADP
bracis-19059	116	6	the	the	DET
bracis-19059	116	7	graph	graph	NOUN
bracis-19059	116	8	-	-	PUNCT
bracis-19059	116	9	based	base	VERB
bracis-19059	116	10	concept	concept	NOUN
bracis-19059	116	11	of	of	ADP
bracis-19059	116	12	cutoff	cutoff	NOUN
bracis-19059	116	13	scanning	scanning	NOUN
bracis-19059	116	14	matrix	matrix	NOUN
bracis-19059	116	15	(	(	PUNCT
bracis-19059	116	16	csm	csm	NOUN
bracis-19059	116	17	)	)	PUNCT
bracis-19059	116	18	,	,	PUNCT
bracis-19059	116	19	originally	originally	ADV
bracis-19059	116	20	proposed	propose	VERB
bracis-19059	116	21	to	to	PART
bracis-19059	116	22	represent	represent	VERB
bracis-19059	116	23	network	network	NOUN
bracis-19059	116	24	topology	topology	NOUN
bracis-19059	116	25	by	by	ADP
bracis-19059	116	26	distance	distance	NOUN
bracis-19059	116	27	patterns	pattern	NOUN
bracis-19059	116	28	in	in	ADP
bracis-19059	116	29	the	the	DET
bracis-19059	116	30	study	study	NOUN
bracis-19059	116	31	of	of	ADP
bracis-19059	116	32	biological	biological	ADJ
bracis-19059	116	33	systems	system	NOUN
bracis-19059	116	34	.	.	PUNCT
bracis-19059	117	1	in	in	ADP
bracis-19059	117	2	mcsm	mcsm	NOUN
bracis-19059	117	3	each	each	DET
bracis-19059	117	4	mutation	mutation	NOUN
bracis-19059	117	5	is	be	AUX
bracis-19059	117	6	represented	represent	VERB
bracis-19059	117	7	by	by	ADP
bracis-19059	117	8	a	a	DET
bracis-19059	117	9	pharmacophore	pharmacophore	ADJ
bracis-19059	117	10	vector	vector	NOUN
bracis-19059	117	11	that	that	PRON
bracis-19059	117	12	is	be	AUX
bracis-19059	117	13	used	use	VERB
bracis-19059	117	14	to	to	PART
bracis-19059	117	15	train	train	VERB
bracis-19059	117	16	and	and	CCONJ
bracis-19059	117	17	test	test	NOUN
bracis-19059	117	18	machine	machine	NOUN
bracis-19059	117	19	learning	learn	VERB
bracis-19059	117	20	prediction	prediction	NOUN
bracis-19059	117	21	methods	method	NOUN
bracis-19059	117	22	,	,	PUNCT
bracis-19059	117	23	both	both	PRON
bracis-19059	117	24	in	in	ADP
bracis-19059	117	25	regression	regression	NOUN
bracis-19059	117	26	and	and	CCONJ
bracis-19059	117	27	predictive	predictive	ADJ
bracis-19059	117	28	classification	classification	NOUN
bracis-19059	117	29	.	.	PUNCT
bracis-19059	118	1	on	on	ADP
bracis-19059	118	2	their	their	PRON
bracis-19059	118	3	proposed	propose	VERB
bracis-19059	118	4	algorithm	algorithm	NOUN
bracis-19059	118	5	,	,	PUNCT
bracis-19059	118	6	first	first	ADJ
bracis-19059	118	7	mcsm	mcsm	NOUN
bracis-19059	118	8	signature	signature	NOUN
bracis-19059	118	9	is	be	AUX
bracis-19059	118	10	calculated	calculate	VERB
bracis-19059	118	11	using	use	VERB
bracis-19059	118	12	a	a	DET
bracis-19059	118	13	set	set	NOUN
bracis-19059	118	14	of	of	ADP
bracis-19059	118	15	mutations	mutation	NOUN
bracis-19059	118	16	,	,	PUNCT
bracis-19059	118	17	wild	wild	ADJ
bracis-19059	118	18	-	-	PUNCT
bracis-19059	118	19	type	type	NOUN
bracis-19059	118	20	structure	structure	NOUN
bracis-19059	118	21	,	,	PUNCT
bracis-19059	118	22	the	the	DET
bracis-19059	118	23	atomic	atomic	ADJ
bracis-19059	118	24	categories	category	NOUN
bracis-19059	118	25	(	(	PUNCT
bracis-19059	118	26	or	or	CCONJ
bracis-19059	118	27	pharmacophore	pharmacophore	NOUN
bracis-19059	118	28	)	)	PUNCT
bracis-19059	118	29	to	to	PART
bracis-19059	118	30	be	be	AUX
bracis-19059	118	31	considered	consider	VERB
bracis-19059	118	32	,	,	PUNCT
bracis-19059	118	33	and	and	CCONJ
bracis-19059	118	34	a	a	DET
bracis-19059	118	35	cutoff	cutoff	NOUN
bracis-19059	118	36	range	range	NOUN
bracis-19059	118	37	and	and	CCONJ
bracis-19059	118	38	step	step	NOUN
bracis-19059	118	39	.	.	PUNCT
bracis-19059	119	1	for	for	ADP
bracis-19059	119	2	each	each	DET
bracis-19059	119	3	mutation	mutation	NOUN
bracis-19059	119	4	,	,	PUNCT
bracis-19059	119	5	based	base	VERB
bracis-19059	119	6	on	on	ADP
bracis-19059	119	7	the	the	DET
bracis-19059	119	8	cutoff	cutoff	NOUN
bracis-19059	119	9	,	,	PUNCT
bracis-19059	119	10	the	the	DET
bracis-19059	119	11	residue	residue	NOUN
bracis-19059	119	12	environment	environment	NOUN
bracis-19059	119	13	is	be	AUX
bracis-19059	119	14	calculated	calculate	VERB
bracis-19059	119	15	,	,	PUNCT
bracis-19059	119	16	followed	follow	VERB
bracis-19059	119	17	by	by	ADP
bracis-19059	119	18	the	the	DET
bracis-19059	119	19	determination	determination	NOUN
bracis-19059	119	20	of	of	ADP
bracis-19059	119	21	a	a	DET
bracis-19059	119	22	distance	distance	NOUN
bracis-19059	119	23	matrix	matrix	NOUN
bracis-19059	119	24	of	of	ADP
bracis-19059	119	25	the	the	DET
bracis-19059	119	26	pairwise	pairwise	NOUN
bracis-19059	119	27	distances	distance	NOUN
bracis-19059	119	28	between	between	ADP
bracis-19059	119	29	all	all	DET
bracis-19059	119	30	pairs	pair	NOUN
bracis-19059	119	31	of	of	ADP
bracis-19059	119	32	atoms	atom	NOUN
bracis-19059	119	33	of	of	ADP
bracis-19059	119	34	the	the	DET
bracis-19059	119	35	residue	residue	NOUN
bracis-19059	119	36	environment	environment	NOUN
bracis-19059	119	37	.	.	PUNCT
bracis-19059	120	1	then	then	ADV
bracis-19059	120	2	,	,	PUNCT
bracis-19059	120	3	the	the	DET
bracis-19059	120	4	distance	distance	NOUN
bracis-19059	120	5	matrix	matrix	NOUN
bracis-19059	120	6	is	be	AUX
bracis-19059	120	7	scanned	scan	VERB
bracis-19059	120	8	using	use	VERB
bracis-19059	120	9	the	the	DET
bracis-19059	120	10	cutoff	cutoff	NOUN
bracis-19059	120	11	range	range	NOUN
bracis-19059	120	12	and	and	CCONJ
bracis-19059	120	13	step	step	NOUN
bracis-19059	120	14	generating	generate	VERB
bracis-19059	120	15	a	a	DET
bracis-19059	120	16	cumulative	cumulative	ADJ
bracis-19059	120	17	distribution	distribution	NOUN
bracis-19059	120	18	of	of	ADP
bracis-19059	120	19	the	the	DET
bracis-19059	120	20	distances	distance	NOUN
bracis-19059	120	21	by	by	ADP
bracis-19059	120	22	atomic	atomic	ADJ
bracis-19059	120	23	category	category	NOUN
bracis-19059	120	24	.	.	PUNCT
bracis-19059	121	1	finally	finally	ADV
bracis-19059	121	2	,	,	PUNCT
bracis-19059	121	3	the	the	DET
bracis-19059	121	4	pharmacophoric	pharmacophoric	ADJ
bracis-19059	121	5	changes	change	NOUN
bracis-19059	121	6	between	between	ADP
bracis-19059	121	7	wild	wild	ADJ
bracis-19059	121	8	-	-	PUNCT
bracis-19059	121	9	type	type	NOUN
bracis-19059	121	10	and	and	CCONJ
bracis-19059	121	11	mutant	mutant	ADJ
bracis-19059	121	12	residue	residue	NOUN
bracis-19059	121	13	are	be	AUX
bracis-19059	121	14	appended	append	VERB
bracis-19059	121	15	to	to	ADP
bracis-19059	121	16	the	the	DET
bracis-19059	121	17	signature	signature	NOUN
bracis-19059	121	18	.	.	PUNCT
bracis-19059	122	1	this	this	DET
bracis-19059	122	2	signatures	signature	NOUN
bracis-19059	122	3	are	be	AUX
bracis-19059	122	4	used	use	VERB
bracis-19059	122	5	for	for	ADP
bracis-19059	122	6	training	train	VERB
bracis-19059	122	7	the	the	DET
bracis-19059	122	8	predictive	predictive	ADJ
bracis-19059	122	9	models	model	NOUN
bracis-19059	122	10	.	.	PUNCT
bracis-19059	123	1	3.4	3.4	NUM
bracis-19059	123	2	duet	duet	NOUN
bracis-19059	123	3	the	the	DET
bracis-19059	123	4	duet	duet	NOUN
bracis-19059	124	1	[	[	X
bracis-19059	124	2	19	19	NUM
bracis-19059	124	3	]	]	X
bracis-19059	124	4	tool	tool	NOUN
bracis-19059	124	5	is	be	AUX
bracis-19059	124	6	an	an	DET
bracis-19059	124	7	integrated	integrate	VERB
bracis-19059	124	8	computational	computational	ADJ
bracis-19059	124	9	approach	approach	NOUN
bracis-19059	124	10	available	available	ADJ
bracis-19059	124	11	online	online	ADV
bracis-19059	124	12	,	,	PUNCT
bracis-19059	124	13	which	which	PRON
bracis-19059	124	14	aims	aim	VERB
bracis-19059	124	15	to	to	PART
bracis-19059	124	16	predict	predict	VERB
bracis-19059	124	17	the	the	DET
bracis-19059	124	18	impact	impact	NOUN
bracis-19059	124	19	of	of	ADP
bracis-19059	124	20	mutations	mutation	NOUN
bracis-19059	124	21	in	in	ADP
bracis-19059	124	22	protein	protein	NOUN
bracis-19059	124	23	stability	stability	NOUN
bracis-19059	124	24	.	.	PUNCT
bracis-19059	125	1	given	give	VERB
bracis-19059	125	2	a	a	DET
bracis-19059	125	3	single	single	ADJ
bracis-19059	125	4	point	point	NOUN
bracis-19059	125	5	mutation	mutation	NOUN
bracis-19059	125	6	,	,	PUNCT
bracis-19059	125	7	duet	duet	NOUN
bracis-19059	125	8	combine	combine	PROPN
bracis-19059	125	9	/	/	SYM
bracis-19059	125	10	consensus	consensus	VERB
bracis-19059	125	11	the	the	DET
bracis-19059	125	12	predictions	prediction	NOUN
bracis-19059	125	13	of	of	ADP
bracis-19059	125	14	two	two	NUM
bracis-19059	125	15	other	other	ADJ
bracis-19059	125	16	tools	tool	NOUN
bracis-19059	125	17	sdm	sdm	NOUN
bracis-19059	125	18	and	and	CCONJ
bracis-19059	125	19	mcsm	mcsm	NOUN
bracis-19059	125	20	in	in	ADP
bracis-19059	125	21	a	a	DET
bracis-19059	125	22	non	non	ADJ
bracis-19059	125	23	-	-	ADJ
bracis-19059	125	24	linear	linear	ADJ
bracis-19059	125	25	way	way	NOUN
bracis-19059	125	26	,	,	PUNCT
bracis-19059	125	27	similar	similar	ADJ
bracis-19059	125	28	to	to	ADP
bracis-19059	125	29	the	the	DET
bracis-19059	125	30	ensemble	ensemble	ADJ
bracis-19059	125	31	learning	learning	NOUN
bracis-19059	125	32	method	method	NOUN
bracis-19059	125	33	,	,	PUNCT
bracis-19059	125	34	to	to	PART
bracis-19059	125	35	make	make	VERB
bracis-19059	125	36	predictions	prediction	NOUN
bracis-19059	125	37	and	and	CCONJ
bracis-19059	125	38	optimize	optimize	VERB
bracis-19059	125	39	results	result	NOUN
bracis-19059	125	40	using	use	VERB
bracis-19059	125	41	support	support	NOUN
bracis-19059	125	42	vector	vector	NOUN
bracis-19059	125	43	machines	machine	NOUN
bracis-19059	125	44	(	(	PUNCT
bracis-19059	125	45	svms	svms	NOUN
bracis-19059	125	46	)	)	PUNCT
bracis-19059	125	47	with	with	ADP
bracis-19059	125	48	radial	radial	ADJ
bracis-19059	125	49	basis	basis	NOUN
bracis-19059	125	50	function	function	NOUN
bracis-19059	125	51	kernel	kernel	NOUN
bracis-19059	125	52	.	.	PUNCT
bracis-19059	126	1	as	as	ADP
bracis-19059	126	2	a	a	DET
bracis-19059	126	3	filtering	filter	VERB
bracis-19059	126	4	step	step	NOUN
bracis-19059	126	5	,	,	PUNCT
bracis-19059	126	6	residue	residue	NOUN
bracis-19059	126	7	relative	relative	ADJ
bracis-19059	126	8	solvent	solvent	NOUN
bracis-19059	126	9	accessibility	accessibility	NOUN
bracis-19059	126	10	(	(	PUNCT
bracis-19059	126	11	rsa	rsa	NOUN
bracis-19059	126	12	)	)	PUNCT
bracis-19059	126	13	is	be	AUX
bracis-19059	126	14	used	use	VERB
bracis-19059	126	15	to	to	PART
bracis-19059	126	16	optimize	optimize	VERB
bracis-19059	126	17	the	the	DET
bracis-19059	126	18	standard	standard	ADJ
bracis-19059	126	19	sdm	sdm	NOUN
bracis-19059	126	20	predictions	prediction	NOUN
bracis-19059	126	21	using	use	VERB
bracis-19059	126	22	a	a	DET
bracis-19059	126	23	regression	regression	NOUN
bracis-19059	126	24	model	model	NOUN
bracis-19059	126	25	tree	tree	NOUN
bracis-19059	126	26	(	(	PUNCT
bracis-19059	126	27	m5p	m5p	NOUN
bracis-19059	126	28	algorithm	algorithm	NOUN
bracis-19059	126	29	)	)	PUNCT
bracis-19059	126	30	before	before	ADP
bracis-19059	126	31	combining	combine	VERB
bracis-19059	126	32	it	it	PRON
bracis-19059	126	33	with	with	ADP
bracis-19059	126	34	mcsm	mcsm	NOUN
bracis-19059	126	35	.	.	PUNCT
bracis-19059	127	1	then	then	ADV
bracis-19059	127	2	,	,	PUNCT
bracis-19059	127	3	the	the	DET
bracis-19059	127	4	mcsm	mcsm	NOUN
bracis-19059	127	5	an	an	DET
bracis-19059	127	6	optimized	optimize	VERB
bracis-19059	127	7	sdm	sdm	NOUN
bracis-19059	127	8	predictions	prediction	NOUN
bracis-19059	127	9	,	,	PUNCT
bracis-19059	127	10	together	together	ADV
bracis-19059	127	11	with	with	ADP
bracis-19059	127	12	secundary	secundary	ADJ
bracis-19059	127	13	structure	structure	NOUN
bracis-19059	127	14	from	from	ADP
bracis-19059	127	15	sdm	sdm	PROPN
bracis-19059	127	16	and	and	CCONJ
bracis-19059	127	17	pharmacophore	pharmacophore	NOUN
bracis-19059	127	18	vector	vector	NOUN
bracis-19059	127	19	from	from	ADP
bracis-19059	127	20	mcsm	mcsm	NOUN
bracis-19059	127	21	are	be	AUX
bracis-19059	127	22	used	use	VERB
bracis-19059	127	23	as	as	ADP
bracis-19059	127	24	input	input	NOUN
bracis-19059	127	25	for	for	ADP
bracis-19059	127	26	svm	svm	NOUN
bracis-19059	127	27	generating	generate	VERB
bracis-19059	127	28	the	the	DET
bracis-19059	127	29	combined	combined	ADJ
bracis-19059	127	30	duet	duet	NOUN
bracis-19059	127	31	output	output	NOUN
bracis-19059	127	32	.	.	PUNCT
bracis-19059	128	1	all	all	DET
bracis-19059	128	2	their	their	PRON
bracis-19059	128	3	training	training	NOUN
bracis-19059	128	4	was	be	AUX
bracis-19059	128	5	carried	carry	VERB
bracis-19059	128	6	out	out	ADP
bracis-19059	128	7	by	by	ADP
bracis-19059	128	8	data	datum	NOUN
bracis-19059	128	9	sets	set	NOUN
bracis-19059	128	10	with	with	ADP
bracis-19059	128	11	little	little	ADJ
bracis-19059	128	12	redundancy	redundancy	NOUN
bracis-19059	128	13	and	and	CCONJ
bracis-19059	128	14	validated	validate	VERB
bracis-19059	128	15	with	with	ADP
bracis-19059	128	16	random	random	ADJ
bracis-19059	128	17	data	data	NOUN
bracis-19059	128	18	sets	set	NOUN
bracis-19059	128	19	.	.	PUNCT
bracis-19059	129	1	3.5	3.5	NUM
bracis-19059	129	2	maestro	maestro	NOUN
bracis-19059	129	3	in	in	ADP
bracis-19059	129	4	order	order	NOUN
bracis-19059	129	5	to	to	PART
bracis-19059	129	6	predict	predict	VERB
bracis-19059	129	7	changes	change	NOUN
bracis-19059	129	8	in	in	ADP
bracis-19059	129	9	stability	stability	NOUN
bracis-19059	129	10	on	on	ADP
bracis-19059	129	11	point	point	NOUN
bracis-19059	129	12	mutations	mutation	NOUN
bracis-19059	129	13	of	of	ADP
bracis-19059	129	14	proteins	protein	NOUN
bracis-19059	129	15	,	,	PUNCT
bracis-19059	129	16	maestro	maestro	NOUN
bracis-19059	129	17	[	[	X
bracis-19059	129	18	14	14	NUM
bracis-19059	129	19	]	]	PUNCT
bracis-19059	129	20	is	be	AUX
bracis-19059	129	21	based	base	VERB
bracis-19059	129	22	on	on	ADP
bracis-19059	129	23	the	the	DET
bracis-19059	129	24	structure	structure	NOUN
bracis-19059	129	25	of	of	ADP
bracis-19059	129	26	the	the	DET
bracis-19059	129	27	protein	protein	NOUN
bracis-19059	129	28	and	and	CCONJ
bracis-19059	129	29	,	,	PUNCT
bracis-19059	129	30	although	although	SCONJ
bracis-19059	129	31	it	it	PRON
bracis-19059	129	32	has	have	VERB
bracis-19059	129	33	a	a	DET
bracis-19059	129	34	predictive	predictive	ADJ
bracis-19059	129	35	similar	similar	ADJ
bracis-19059	129	36	to	to	ADP
bracis-19059	129	37	other	other	ADJ
bracis-19059	129	38	methods	method	NOUN
bracis-19059	129	39	,	,	PUNCT
bracis-19059	129	40	it	it	PRON
bracis-19059	129	41	differs	differ	VERB
bracis-19059	129	42	because	because	SCONJ
bracis-19059	129	43	of	of	ADP
bracis-19059	129	44	the	the	DET
bracis-19059	129	45	following	following	ADJ
bracis-19059	129	46	points	point	NOUN
bracis-19059	129	47	:	:	PUNCT
bracis-19059	129	48	it	it	PRON
bracis-19059	129	49	implements	implement	VERB
bracis-19059	129	50	a	a	DET
bracis-19059	129	51	multi	multi	ADJ
bracis-19059	129	52	-	-	ADJ
bracis-19059	129	53	agent	agent	ADJ
bracis-19059	129	54	system	system	NOUN
bracis-19059	129	55	for	for	ADP
bracis-19059	129	56	learning	learning	NOUN
bracis-19059	129	57	;	;	PUNCT
bracis-19059	129	58	provides	provide	VERB
bracis-19059	129	59	in	in	ADP
bracis-19059	129	60	-	-	PUNCT
bracis-19059	129	61	depth	depth	NOUN
bracis-19059	129	62	mutation	mutation	NOUN
bracis-19059	129	63	scanning	scanning	NOUN
bracis-19059	129	64	at	at	ADP
bracis-19059	129	65	various	various	ADJ
bracis-19059	129	66	points	point	NOUN
bracis-19059	129	67	where	where	SCONJ
bracis-19059	129	68	mutation	mutation	NOUN
bracis-19059	129	69	types	type	NOUN
bracis-19059	129	70	can	can	AUX
bracis-19059	129	71	be	be	AUX
bracis-19059	129	72	comprehensively	comprehensively	ADV
bracis-19059	129	73	controlled	control	VERB
bracis-19059	129	74	;	;	PUNCT
bracis-19059	129	75	and	and	CCONJ
bracis-19059	129	76	provides	provide	VERB
bracis-19059	129	77	a	a	DET
bracis-19059	129	78	specific	specific	ADJ
bracis-19059	129	79	mode	mode	NOUN
bracis-19059	129	80	for	for	ADP
bracis-19059	129	81	stabilizing	stabilize	VERB
bracis-19059	129	82	disulfide	disulfide	NOUN
bracis-19059	129	83	bond	bond	NOUN
bracis-19059	129	84	predictions	prediction	NOUN
bracis-19059	129	85	.	.	PUNCT
bracis-19059	130	1	maestro	maestro	NOUN
bracis-19059	130	2	is	be	AUX
bracis-19059	130	3	based	base	VERB
bracis-19059	130	4	on	on	ADP
bracis-19059	130	5	two	two	NUM
bracis-19059	130	6	different	different	ADJ
bracis-19059	130	7	machine	machine	NOUN
bracis-19059	130	8	learning	learning	NOUN
bracis-19059	130	9	approaches	approach	NOUN
bracis-19059	130	10	:	:	PUNCT
bracis-19059	130	11	artificial	artificial	ADJ
bracis-19059	130	12	neural	neural	ADJ
bracis-19059	130	13	networks	network	NOUN
bracis-19059	130	14	(	(	PUNCT
bracis-19059	130	15	ann	ann	PROPN
bracis-19059	130	16	)	)	PUNCT
bracis-19059	130	17	and	and	CCONJ
bracis-19059	130	18	svm	svm	PROPN
bracis-19059	130	19	(	(	PUNCT
bracis-19059	130	20	gaussian	gaussian	ADJ
bracis-19059	130	21	kernel	kernel	NOUN
bracis-19059	130	22	)	)	PUNCT
bracis-19059	130	23	,	,	PUNCT
bracis-19059	130	24	and	and	CCONJ
bracis-19059	130	25	also	also	ADV
bracis-19059	130	26	on	on	ADP
bracis-19059	130	27	multiple	multiple	ADJ
bracis-19059	130	28	linear	linear	ADJ
bracis-19059	130	29	regression	regression	NOUN
bracis-19059	130	30	(	(	PUNCT
bracis-19059	130	31	mlr	mlr	NOUN
bracis-19059	130	32	)	)	PUNCT
bracis-19059	130	33	.	.	PUNCT
bracis-19059	131	1	in	in	ADP
bracis-19059	131	2	order	order	NOUN
bracis-19059	131	3	to	to	PART
bracis-19059	131	4	improve	improve	VERB
bracis-19059	131	5	generalization	generalization	NOUN
bracis-19059	131	6	,	,	PUNCT
bracis-19059	131	7	a	a	DET
bracis-19059	131	8	set	set	NOUN
bracis-19059	131	9	of	of	ADP
bracis-19059	131	10	anns	anns	NOUN
bracis-19059	131	11	is	be	AUX
bracis-19059	131	12	utilized	utilize	VERB
bracis-19059	131	13	rather	rather	ADV
bracis-19059	131	14	than	than	ADP
bracis-19059	131	15	a	a	DET
bracis-19059	131	16	single	single	ADJ
bracis-19059	131	17	one	one	NUM
bracis-19059	131	18	.	.	PUNCT
bracis-19059	131	19	3.6	3.6	NUM
bracis-19059	131	20	popmusic	popmusic	ADJ
bracis-19059	131	21	popmusic	popmusic	NOUN
bracis-19059	131	22	[	[	X
bracis-19059	131	23	7	7	NUM
bracis-19059	131	24	]	]	PUNCT
bracis-19059	131	25	is	be	AUX
bracis-19059	131	26	a	a	DET
bracis-19059	131	27	web	web	NOUN
bracis-19059	131	28	server	server	NOUN
bracis-19059	131	29	for	for	ADP
bracis-19059	131	30	predicting	predict	VERB
bracis-19059	131	31	thermodynamic	thermodynamic	ADJ
bracis-19059	131	32	changes	change	NOUN
bracis-19059	131	33	in	in	ADP
bracis-19059	131	34	point	point	NOUN
bracis-19059	131	35	mutations	mutation	NOUN
bracis-19059	131	36	of	of	ADP
bracis-19059	131	37	proteins	protein	NOUN
bracis-19059	131	38	,	,	PUNCT
bracis-19059	131	39	which	which	PRON
bracis-19059	131	40	uses	use	VERB
bracis-19059	131	41	a	a	DET
bracis-19059	131	42	linear	linear	ADJ
bracis-19059	131	43	combination	combination	NOUN
bracis-19059	131	44	of	of	ADP
bracis-19059	131	45	statistical	statistical	ADJ
bracis-19059	131	46	potentials	potential	NOUN
bracis-19059	131	47	whose	whose	DET
bracis-19059	131	48	coefficients	coefficient	NOUN
bracis-19059	131	49	depend	depend	VERB
bracis-19059	131	50	on	on	ADP
bracis-19059	131	51	the	the	DET
bracis-19059	131	52	solvent	solvent	ADJ
bracis-19059	131	53	accessibility	accessibility	NOUN
bracis-19059	131	54	of	of	ADP
bracis-19059	131	55	the	the	DET
bracis-19059	131	56	mutated	mutate	VERB
bracis-19059	131	57	residue	residue	NOUN
bracis-19059	131	58	.	.	PUNCT
bracis-19059	132	1	it	it	PRON
bracis-19059	132	2	is	be	AUX
bracis-19059	132	3	a	a	DET
bracis-19059	132	4	fast	fast	ADJ
bracis-19059	132	5	tool	tool	NOUN
bracis-19059	132	6	that	that	PRON
bracis-19059	132	7	allows	allow	VERB
bracis-19059	132	8	you	you	PRON
bracis-19059	132	9	to	to	PART
bracis-19059	132	10	make	make	VERB
bracis-19059	132	11	predictions	prediction	NOUN
bracis-19059	132	12	for	for	ADP
bracis-19059	132	13	all	all	DET
bracis-19059	132	14	possible	possible	ADJ
bracis-19059	132	15	mutations	mutation	NOUN
bracis-19059	132	16	of	of	ADP
bracis-19059	132	17	a	a	DET
bracis-19059	132	18	protein	protein	NOUN
bracis-19059	132	19	,	,	PUNCT
bracis-19059	132	20	average	average	ADJ
bracis-19059	132	21	size	size	NOUN
bracis-19059	132	22	,	,	PUNCT
bracis-19059	132	23	in	in	ADP
bracis-19059	132	24	less	less	ADJ
bracis-19059	132	25	than	than	ADP
bracis-19059	132	26	a	a	DET
bracis-19059	132	27	minute	minute	NOUN
bracis-19059	132	28	.	.	PUNCT
bracis-19059	133	1	it	it	PRON
bracis-19059	133	2	has	have	VERB
bracis-19059	133	3	the	the	DET
bracis-19059	133	4	ability	ability	NOUN
bracis-19059	133	5	to	to	PART
bracis-19059	133	6	detect	detect	VERB
bracis-19059	133	7	which	which	PRON
bracis-19059	133	8	and	and	CCONJ
bracis-19059	133	9	how	how	SCONJ
bracis-19059	133	10	optimal	optimal	ADJ
bracis-19059	133	11	the	the	DET
bracis-19059	133	12	amino	amino	ADJ
bracis-19059	133	13	acids	acid	NOUN
bracis-19059	133	14	are	be	AUX
bracis-19059	133	15	in	in	ADP
bracis-19059	133	16	each	each	DET
bracis-19059	133	17	protein	protein	NOUN
bracis-19059	133	18	,	,	PUNCT
bracis-19059	133	19	so	so	SCONJ
bracis-19059	133	20	that	that	SCONJ
bracis-19059	133	21	mutation	mutation	NOUN
bracis-19059	133	22	experiments	experiment	NOUN
bracis-19059	133	23	can	can	AUX
bracis-19059	133	24	be	be	AUX
bracis-19059	133	25	carried	carry	VERB
bracis-19059	133	26	out	out	ADP
bracis-19059	133	27	,	,	PUNCT
bracis-19059	133	28	also	also	ADV
bracis-19059	133	29	demonstrating	demonstrate	VERB
bracis-19059	133	30	structural	structural	ADJ
bracis-19059	133	31	weaknesses	weakness	NOUN
bracis-19059	133	32	by	by	ADP
bracis-19059	133	33	quantifying	quantify	VERB
bracis-19059	133	34	how	how	SCONJ
bracis-19059	133	35	much	much	ADJ
bracis-19059	133	36	these	these	DET
bracis-19059	133	37	sites	site	NOUN
bracis-19059	133	38	are	be	AUX
bracis-19059	133	39	optimized	optimize	VERB
bracis-19059	133	40	for	for	ADP
bracis-19059	133	41	protein	protein	NOUN
bracis-19059	133	42	function	function	NOUN
bracis-19059	133	43	,	,	PUNCT
bracis-19059	133	44	rather	rather	ADV
bracis-19059	133	45	than	than	ADP
bracis-19059	133	46	stability	stability	NOUN
bracis-19059	133	47	.	.	PUNCT
bracis-19059	134	1	4	4	NUM
bracis-19059	134	2	proposed	propose	VERB
bracis-19059	134	3	methodology	methodology	NOUN
bracis-19059	134	4	our	our	PRON
bracis-19059	134	5	proposed	propose	VERB
bracis-19059	134	6	methodology	methodology	NOUN
bracis-19059	134	7	is	be	AUX
bracis-19059	134	8	presented	present	VERB
bracis-19059	134	9	in	in	ADP
bracis-19059	134	10	fig	fig	NOUN
bracis-19059	134	11	.	.	PUNCT
bracis-19059	134	12	 	 	SPACE
bracis-19059	135	1	1	1	X
bracis-19059	135	2	.	.	PUNCT
bracis-19059	136	1	we	we	PRON
bracis-19059	136	2	are	be	AUX
bracis-19059	136	3	applying	apply	VERB
bracis-19059	136	4	stacking	stacking	NOUN
bracis-19059	136	5	and	and	CCONJ
bracis-19059	136	6	bagging	bagging	NOUN
bracis-19059	136	7	/	/	SYM
bracis-19059	136	8	boosting	boost	VERB
bracis-19059	136	9	ensemble	ensemble	ADJ
bracis-19059	136	10	learning	learning	NOUN
bracis-19059	136	11	on	on	ADP
bracis-19059	136	12	the	the	DET
bracis-19059	136	13	results	result	NOUN
bracis-19059	136	14	of	of	ADP
bracis-19059	136	15	six	six	NUM
bracis-19059	136	16	protein	protein	NOUN
bracis-19059	136	17	stability	stability	NOUN
bracis-19059	136	18	changes	change	VERB
bracis-19059	136	19	upon	upon	SCONJ
bracis-19059	136	20	point	point	NOUN
bracis-19059	136	21	mutations	mutation	NOUN
bracis-19059	136	22	predictors	predictor	NOUN
bracis-19059	136	23	:	:	PUNCT
bracis-19059	136	24	cupsat	cupsat	VERB
bracis-19059	136	25	[	[	PUNCT
bracis-19059	136	26	17	17	NUM
bracis-19059	136	27	]	]	PUNCT
bracis-19059	136	28	,	,	PUNCT
bracis-19059	136	29	sdm	sdm	PROPN
bracis-19059	137	1	[	[	X
bracis-19059	137	2	25	25	NUM
bracis-19059	137	3	]	]	PUNCT
bracis-19059	137	4	,	,	PUNCT
bracis-19059	137	5	mcsm	mcsm	NOUN
bracis-19059	137	6	[	[	X
bracis-19059	137	7	18	18	NUM
bracis-19059	137	8	]	]	PUNCT
bracis-19059	137	9	,	,	PUNCT
bracis-19059	137	10	duet	duet	NOUN
bracis-19059	137	11	[	[	X
bracis-19059	137	12	19	19	NUM
bracis-19059	137	13	]	]	PUNCT
bracis-19059	137	14	,	,	PUNCT
bracis-19059	137	15	maestro	maestro	NOUN
bracis-19059	137	16	[	[	X
bracis-19059	137	17	14	14	NUM
bracis-19059	137	18	]	]	PUNCT
bracis-19059	137	19	and	and	CCONJ
bracis-19059	137	20	popmusic	popmusic	ADJ
bracis-19059	138	1	[	[	X
bracis-19059	138	2	7	7	NUM
bracis-19059	138	3	]	]	PUNCT
bracis-19059	138	4	.	.	PUNCT
bracis-19059	139	1	fig	fig	NOUN
bracis-19059	139	2	.	.	PUNCT
bracis-19059	140	1	1	1	X
bracis-19059	140	2	.	.	NUM
bracis-19059	140	3	proposed	propose	VERB
bracis-19059	140	4	methodology	methodology	NOUN
bracis-19059	140	5	of	of	ADP
bracis-19059	140	6	ensemble	ensemble	ADJ
bracis-19059	140	7	learning	learning	NOUN
bracis-19059	140	8	applied	apply	VERB
bracis-19059	140	9	on	on	ADP
bracis-19059	140	10	protein	protein	NOUN
bracis-19059	140	11	stability	stability	NOUN
bracis-19059	140	12	changes	change	VERB
bracis-19059	140	13	upon	upon	SCONJ
bracis-19059	140	14	point	point	NOUN
bracis-19059	140	15	mutations	mutation	NOUN
bracis-19059	140	16	predictors	predictor	NOUN
bracis-19059	140	17	.	.	PUNCT
bracis-19059	141	1	full	full	ADJ
bracis-19059	141	2	size	size	NOUN
bracis-19059	141	3	image	image	NOUN
bracis-19059	141	4	4.1	4.1	NUM
bracis-19059	141	5	input	input	NOUN
bracis-19059	141	6	data	datum	NOUN
bracis-19059	141	7	the	the	DET
bracis-19059	141	8	first	first	ADJ
bracis-19059	141	9	step	step	NOUN
bracis-19059	141	10	on	on	ADP
bracis-19059	141	11	our	our	PRON
bracis-19059	141	12	proposed	propose	VERB
bracis-19059	141	13	methodology	methodology	NOUN
bracis-19059	141	14	is	be	AUX
bracis-19059	141	15	to	to	PART
bracis-19059	141	16	prepare	prepare	VERB
bracis-19059	141	17	the	the	DET
bracis-19059	141	18	input	input	NOUN
bracis-19059	141	19	dataset	dataset	NOUN
bracis-19059	141	20	.	.	PUNCT
bracis-19059	142	1	in	in	ADP
bracis-19059	142	2	this	this	DET
bracis-19059	142	3	paper	paper	NOUN
bracis-19059	142	4	we	we	PRON
bracis-19059	142	5	are	be	AUX
bracis-19059	142	6	considering	consider	VERB
bracis-19059	142	7	as	as	ADP
bracis-19059	142	8	input	input	NOUN
bracis-19059	142	9	data	data	NOUN
bracis-19059	142	10	sets	set	NOUN
bracis-19059	142	11	of	of	ADP
bracis-19059	142	12	proteins	protein	NOUN
bracis-19059	142	13	from	from	ADP
bracis-19059	142	14	which	which	PRON
bracis-19059	142	15	we	we	PRON
bracis-19059	142	16	can	can	AUX
bracis-19059	142	17	obtain	obtain	VERB
bracis-19059	142	18	the	the	DET
bracis-19059	142	19	experimental	experimental	ADJ
bracis-19059	142	20	value	value	NOUN
bracis-19059	142	21	of	of	ADP
bracis-19059	142	22	gibbs	gibbs	PROPN
bracis-19059	142	23	free	free	ADJ
bracis-19059	142	24	energy	energy	NOUN
bracis-19059	142	25	(	(	PUNCT
bracis-19059	142	26	\(\vardelta	\(\vardelta	X
bracis-19059	142	27	\vardelta	\vardelta	NOUN
bracis-19059	142	28	\)g	\)g	NOUN
bracis-19059	142	29	)	)	PUNCT
bracis-19059	142	30	between	between	ADP
bracis-19059	142	31	wild	wild	ADJ
bracis-19059	142	32	-	-	PUNCT
bracis-19059	142	33	type	type	NOUN
bracis-19059	142	34	and	and	CCONJ
bracis-19059	142	35	mutants	mutant	NOUN
bracis-19059	142	36	(	(	PUNCT
bracis-19059	142	37	our	our	PRON
bracis-19059	142	38	target	target	NOUN
bracis-19059	142	39	attribute	attribute	NOUN
bracis-19059	142	40	on	on	ADP
bracis-19059	142	41	ensemble	ensemble	ADJ
bracis-19059	142	42	learning	learning	NOUN
bracis-19059	142	43	)	)	PUNCT
bracis-19059	142	44	.	.	PUNCT
bracis-19059	143	1	this	this	DET
bracis-19059	143	2	thermodynamic	thermodynamic	ADJ
bracis-19059	143	3	experimental	experimental	ADJ
bracis-19059	143	4	data	datum	NOUN
bracis-19059	143	5	was	be	AUX
bracis-19059	143	6	obtained	obtain	VERB
bracis-19059	143	7	from	from	ADP
bracis-19059	143	8	protherm	protherm	NOUN
bracis-19059	143	9	[	[	X
bracis-19059	143	10	2	2	NUM
bracis-19059	143	11	]	]	PUNCT
bracis-19059	143	12	.	.	PUNCT
bracis-19059	144	1	protherm	protherm	NOUN
bracis-19059	144	2	is	be	AUX
bracis-19059	144	3	a	a	DET
bracis-19059	144	4	database	database	NOUN
bracis-19059	144	5	containing	contain	VERB
bracis-19059	144	6	several	several	ADJ
bracis-19059	144	7	thermodynamic	thermodynamic	ADJ
bracis-19059	144	8	parameters	parameter	NOUN
bracis-19059	144	9	along	along	ADP
bracis-19059	144	10	with	with	ADP
bracis-19059	144	11	sequence	sequence	NOUN
bracis-19059	144	12	and	and	CCONJ
bracis-19059	144	13	structural	structural	ADJ
bracis-19059	144	14	information	information	NOUN
bracis-19059	144	15	,	,	PUNCT
bracis-19059	144	16	experimental	experimental	ADJ
bracis-19059	144	17	methods	method	NOUN
bracis-19059	144	18	and	and	CCONJ
bracis-19059	144	19	conditions	condition	NOUN
bracis-19059	144	20	parameters	parameter	NOUN
bracis-19059	144	21	for	for	ADP
bracis-19059	144	22	wild	wild	ADJ
bracis-19059	144	23	-	-	PUNCT
bracis-19059	144	24	type	type	NOUN
bracis-19059	144	25	and	and	CCONJ
bracis-19059	144	26	mutant	mutant	ADJ
bracis-19059	144	27	proteins	protein	NOUN
bracis-19059	144	28	.	.	PUNCT
bracis-19059	145	1	the	the	DET
bracis-19059	145	2	non	non	ADJ
bracis-19059	145	3	-	-	ADJ
bracis-19059	145	4	disjoint	disjoint	ADJ
bracis-19059	145	5	datasets	dataset	NOUN
bracis-19059	145	6	ds1	ds1	PROPN
bracis-19059	145	7	,	,	PUNCT
bracis-19059	145	8	ds2648	ds2648	PROPN
bracis-19059	145	9	and	and	CCONJ
bracis-19059	145	10	ds1948	ds1948	PROPN
bracis-19059	145	11	,	,	PUNCT
bracis-19059	145	12	table	table	NOUN
bracis-19059	145	13	 	 	SPACE
bracis-19059	145	14	1	1	NUM
bracis-19059	145	15	lines	line	NOUN
bracis-19059	145	16	1–3	1–3	NUM
bracis-19059	145	17	,	,	PUNCT
bracis-19059	145	18	are	be	AUX
bracis-19059	145	19	taken	take	VERB
bracis-19059	145	20	from	from	ADP
bracis-19059	145	21	protherm	protherm	NOUN
bracis-19059	145	22	[	[	X
bracis-19059	145	23	2	2	NUM
bracis-19059	145	24	]	]	PUNCT
bracis-19059	145	25	and	and	CCONJ
bracis-19059	145	26	considered	consider	VERB
bracis-19059	145	27	in	in	ADP
bracis-19059	145	28	the	the	DET
bracis-19059	145	29	individual	individual	ADJ
bracis-19059	145	30	tools	tool	NOUN
bracis-19059	145	31	for	for	ADP
bracis-19059	145	32	training	train	VERB
bracis-19059	145	33	their	their	PRON
bracis-19059	145	34	models	model	NOUN
bracis-19059	145	35	.	.	PUNCT
bracis-19059	146	1	ds1	ds1	PROPN
bracis-19059	146	2	and	and	CCONJ
bracis-19059	146	3	ds2648	ds2648	PROPN
bracis-19059	146	4	were	be	AUX
bracis-19059	146	5	used	use	VERB
bracis-19059	146	6	by	by	ADP
bracis-19059	146	7	popmusic	popmusic	NOUN
bracis-19059	146	8	[	[	X
bracis-19059	146	9	7	7	NUM
bracis-19059	146	10	]	]	PUNCT
bracis-19059	146	11	,	,	PUNCT
bracis-19059	146	12	sdm	sdm	PROPN
bracis-19059	147	1	[	[	X
bracis-19059	147	2	25	25	NUM
bracis-19059	147	3	]	]	PUNCT
bracis-19059	147	4	and	and	CCONJ
bracis-19059	147	5	maestro	maestro	NOUN
bracis-19059	147	6	[	[	X
bracis-19059	147	7	14	14	NUM
bracis-19059	147	8	]	]	PUNCT
bracis-19059	147	9	,	,	PUNCT
bracis-19059	147	10	while	while	SCONJ
bracis-19059	147	11	ds1948	ds1948	PROPN
bracis-19059	147	12	was	be	AUX
bracis-19059	147	13	used	use	VERB
bracis-19059	147	14	by	by	ADP
bracis-19059	147	15	i	i	NOUN
bracis-19059	147	16	-	-	PUNCT
bracis-19059	147	17	mutant	mutant	NOUN
bracis-19059	147	18	[	[	X
bracis-19059	147	19	4	4	NUM
bracis-19059	147	20	]	]	X
bracis-19059	147	21	tool	tool	NOUN
bracis-19059	147	22	.	.	PUNCT
bracis-19059	148	1	these	these	DET
bracis-19059	148	2	three	three	NUM
bracis-19059	148	3	datasets	dataset	NOUN
bracis-19059	148	4	ds1	ds1	PROPN
bracis-19059	148	5	,	,	PUNCT
bracis-19059	148	6	ds2648	ds2648	PROPN
bracis-19059	148	7	and	and	CCONJ
bracis-19059	148	8	ds1948	ds1948	PROPN
bracis-19059	148	9	have	have	VERB
bracis-19059	148	10	different	different	ADJ
bracis-19059	148	11	formats	format	NOUN
bracis-19059	148	12	for	for	ADP
bracis-19059	148	13	presenting	present	VERB
bracis-19059	148	14	their	their	PRON
bracis-19059	148	15	data	datum	NOUN
bracis-19059	148	16	,	,	PUNCT
bracis-19059	148	17	in	in	ADP
bracis-19059	148	18	addition	addition	NOUN
bracis-19059	148	19	to	to	ADP
bracis-19059	148	20	containing	contain	VERB
bracis-19059	148	21	several	several	ADJ
bracis-19059	148	22	duplicates	duplicate	NOUN
bracis-19059	148	23	.	.	PUNCT
bracis-19059	149	1	thus	thus	ADV
bracis-19059	149	2	,	,	PUNCT
bracis-19059	149	3	we	we	PRON
bracis-19059	149	4	unified	unify	VERB
bracis-19059	149	5	and	and	CCONJ
bracis-19059	149	6	preprocess	preprocess	NOUN
bracis-19059	149	7	all	all	DET
bracis-19059	149	8	these	these	DET
bracis-19059	149	9	data	datum	NOUN
bracis-19059	149	10	totaling	total	VERB
bracis-19059	149	11	7244	7244	NUM
bracis-19059	149	12	instances	instance	NOUN
bracis-19059	149	13	(	(	PUNCT
bracis-19059	149	14	4th	4th	ADJ
bracis-19059	149	15	line	line	NOUN
bracis-19059	149	16	on	on	ADP
bracis-19059	149	17	table	table	NOUN
bracis-19059	149	18	 	 	SPACE
bracis-19059	149	19	1	1	NUM
bracis-19059	149	20	)	)	PUNCT
bracis-19059	149	21	.	.	PUNCT
bracis-19059	150	1	after	after	ADP
bracis-19059	150	2	preprocessing	preprocesse	VERB
bracis-19059	150	3	all	all	DET
bracis-19059	150	4	these	these	DET
bracis-19059	150	5	data	datum	NOUN
bracis-19059	150	6	,	,	PUNCT
bracis-19059	150	7	we	we	PRON
bracis-19059	150	8	remove	remove	VERB
bracis-19059	150	9	duplicates	duplicate	NOUN
bracis-19059	150	10	of	of	ADP
bracis-19059	150	11	the	the	DET
bracis-19059	150	12	same	same	ADJ
bracis-19059	150	13	protein	protein	NOUN
bracis-19059	150	14	experimental	experimental	ADJ
bracis-19059	150	15	results	result	NOUN
bracis-19059	150	16	resulting	result	VERB
bracis-19059	150	17	in	in	ADP
bracis-19059	150	18	our	our	PRON
bracis-19059	150	19	final	final	ADJ
bracis-19059	150	20	input	input	NOUN
bracis-19059	150	21	dataset	dataset	VERB
bracis-19059	150	22	ds3904	ds3904	PROPN
bracis-19059	150	23	(	(	PUNCT
bracis-19059	150	24	highlighted	highlight	VERB
bracis-19059	150	25	on	on	ADP
bracis-19059	150	26	table	table	NOUN
bracis-19059	150	27	 	 	SPACE
bracis-19059	150	28	1	1	NUM
bracis-19059	150	29	)	)	PUNCT
bracis-19059	150	30	.	.	PUNCT
bracis-19059	151	1	table	table	NOUN
bracis-19059	151	2	1	1	NUM
bracis-19059	151	3	.	.	PUNCT
bracis-19059	152	1	input	input	NOUN
bracis-19059	152	2	datasets	dataset	NOUN
bracis-19059	152	3	:	:	PUNCT
bracis-19059	152	4	number	number	NOUN
bracis-19059	152	5	of	of	ADP
bracis-19059	152	6	instances	instance	NOUN
bracis-19059	152	7	,	,	PUNCT
bracis-19059	152	8	number	number	NOUN
bracis-19059	152	9	of	of	ADP
bracis-19059	152	10	unique	unique	ADJ
bracis-19059	152	11	proteins	protein	NOUN
bracis-19059	152	12	,	,	PUNCT
bracis-19059	152	13	number	number	NOUN
bracis-19059	152	14	of	of	ADP
bracis-19059	152	15	stabilizing	stabilize	VERB
bracis-19059	152	16	mutations	mutation	NOUN
bracis-19059	152	17	and	and	CCONJ
bracis-19059	152	18	number	number	NOUN
bracis-19059	152	19	of	of	ADP
bracis-19059	152	20	destabilizing	destabilizing	ADJ
bracis-19059	152	21	mutations.full	mutations.full	NOUN
bracis-19059	152	22	size	size	NOUN
bracis-19059	152	23	table	table	NOUN
bracis-19059	152	24	4.2	4.2	NUM
bracis-19059	152	25	meta	meta	NOUN
bracis-19059	152	26	data	datum	NOUN
bracis-19059	152	27	after	after	ADP
bracis-19059	152	28	having	have	VERB
bracis-19059	152	29	ds3904	ds3904	PROPN
bracis-19059	152	30	properly	properly	ADV
bracis-19059	152	31	prepared	prepare	VERB
bracis-19059	152	32	,	,	PUNCT
bracis-19059	152	33	the	the	DET
bracis-19059	152	34	following	follow	VERB
bracis-19059	152	35	step	step	NOUN
bracis-19059	152	36	is	be	AUX
bracis-19059	152	37	submitting	submit	VERB
bracis-19059	152	38	this	this	DET
bracis-19059	152	39	list	list	NOUN
bracis-19059	152	40	of	of	ADP
bracis-19059	152	41	protein	protein	NOUN
bracis-19059	152	42	wild	wild	ADJ
bracis-19059	152	43	-	-	PUNCT
bracis-19059	152	44	type	type	NOUN
bracis-19059	152	45	/	/	SYM
bracis-19059	152	46	mutations	mutation	NOUN
bracis-19059	152	47	in	in	ADP
bracis-19059	152	48	each	each	PRON
bracis-19059	152	49	of	of	ADP
bracis-19059	152	50	the	the	DET
bracis-19059	152	51	tools	tool	NOUN
bracis-19059	152	52	.	.	PUNCT
bracis-19059	153	1	in	in	ADP
bracis-19059	153	2	fig	fig	NOUN
bracis-19059	153	3	.	.	PUNCT
bracis-19059	153	4	 	 	SPACE
bracis-19059	153	5	2(a	2(a	NOUN
bracis-19059	153	6	)	)	PUNCT
bracis-19059	154	1	we	we	PRON
bracis-19059	154	2	describe	describe	VERB
bracis-19059	154	3	a	a	DET
bracis-19059	154	4	part	part	NOUN
bracis-19059	154	5	of	of	ADP
bracis-19059	154	6	ds3904	ds3904	PROPN
bracis-19059	154	7	where	where	SCONJ
bracis-19059	154	8	we	we	PRON
bracis-19059	154	9	have	have	VERB
bracis-19059	154	10	the	the	DET
bracis-19059	154	11	pdb	pdb	PROPN
bracis-19059	154	12	i	i	PROPN
bracis-19059	154	13	d	d	PROPN
bracis-19059	154	14	,	,	PUNCT
bracis-19059	154	15	the	the	DET
bracis-19059	154	16	mutation	mutation	NOUN
bracis-19059	154	17	in	in	ADP
bracis-19059	154	18	the	the	DET
bracis-19059	154	19	format	format	NOUN
bracis-19059	154	20	original	original	ADJ
bracis-19059	154	21	residue	residue	NOUN
bracis-19059	154	22	type	type	NOUN
bracis-19059	154	23	position	position	NOUN
bracis-19059	154	24	mutation	mutation	NOUN
bracis-19059	154	25	and	and	CCONJ
bracis-19059	154	26	the	the	DET
bracis-19059	154	27	experimental	experimental	ADJ
bracis-19059	154	28	\(\vardelta	\(\vardelta	NOUN
bracis-19059	154	29	\vardelta	\vardelta	ADP
bracis-19059	154	30	\)g	\)g	NOUN
bracis-19059	154	31	.	.	PUNCT
bracis-19059	155	1	for	for	ADP
bracis-19059	155	2	example	example	NOUN
bracis-19059	155	3	,	,	PUNCT
bracis-19059	155	4	the	the	DET
bracis-19059	155	5	first	first	ADJ
bracis-19059	155	6	line	line	NOUN
bracis-19059	155	7	,	,	PUNCT
bracis-19059	155	8	pdb	pdb	PROPN
bracis-19059	155	9	i	i	PROPN
bracis-19059	155	10	d	d	PROPN
bracis-19059	155	11	1a23	1a23	INTJ
bracis-19059	155	12	has	have	VERB
bracis-19059	155	13	as	as	ADP
bracis-19059	155	14	original	original	ADJ
bracis-19059	155	15	residue	residue	NOUN
bracis-19059	155	16	in	in	ADP
bracis-19059	155	17	position	position	NOUN
bracis-19059	155	18	32	32	NUM
bracis-19059	155	19	a	a	DET
bracis-19059	155	20	histidine	histidine	NOUN
bracis-19059	155	21	(	(	PUNCT
bracis-19059	155	22	h	h	NOUN
bracis-19059	155	23	)	)	PUNCT
bracis-19059	155	24	that	that	SCONJ
bracis-19059	155	25	when	when	SCONJ
bracis-19059	155	26	mutated	mutate	VERB
bracis-19059	155	27	to	to	ADP
bracis-19059	155	28	a	a	DET
bracis-19059	155	29	leucine	leucine	NOUN
bracis-19059	155	30	(	(	PUNCT
bracis-19059	155	31	l	l	NOUN
bracis-19059	155	32	)	)	PUNCT
bracis-19059	155	33	has	have	VERB
bracis-19059	155	34	an	an	DET
bracis-19059	155	35	experimental	experimental	ADJ
bracis-19059	155	36	\(\vardelta	\(\vardelta	NOUN
bracis-19059	155	37	\vardelta	\vardelta	NOUN
bracis-19059	155	38	\)g	\)g	NOUN
bracis-19059	155	39	of	of	ADP
bracis-19059	155	40	4.6	4.6	NUM
bracis-19059	155	41	.	.	PUNCT
bracis-19059	156	1	in	in	ADP
bracis-19059	156	2	order	order	NOUN
bracis-19059	156	3	to	to	PART
bracis-19059	156	4	obtain	obtain	VERB
bracis-19059	156	5	the	the	DET
bracis-19059	156	6	predicted	predict	VERB
bracis-19059	156	7	\(\vardelta	\(\vardelta	NOUN
bracis-19059	156	8	\vardelta	\vardelta	NOUN
bracis-19059	156	9	\)g	\)g	NOUN
bracis-19059	156	10	of	of	ADP
bracis-19059	156	11	each	each	DET
bracis-19059	156	12	tool	tool	NOUN
bracis-19059	156	13	to	to	PART
bracis-19059	156	14	generate	generate	VERB
bracis-19059	156	15	our	our	PRON
bracis-19059	156	16	meta	meta	ADJ
bracis-19059	156	17	data	datum	NOUN
bracis-19059	156	18	we	we	PRON
bracis-19059	156	19	would	would	AUX
bracis-19059	156	20	need	need	VERB
bracis-19059	156	21	to	to	PART
bracis-19059	156	22	manually	manually	ADV
bracis-19059	156	23	submit	submit	VERB
bracis-19059	156	24	each	each	DET
bracis-19059	156	25	entry	entry	NOUN
bracis-19059	156	26	of	of	ADP
bracis-19059	156	27	ds3904	ds3904	PROPN
bracis-19059	156	28	to	to	ADP
bracis-19059	156	29	the	the	DET
bracis-19059	156	30	tools	tool	NOUN
bracis-19059	156	31	.	.	PUNCT
bracis-19059	157	1	to	to	PART
bracis-19059	157	2	perform	perform	VERB
bracis-19059	157	3	this	this	DET
bracis-19059	157	4	task	task	NOUN
bracis-19059	157	5	in	in	ADP
bracis-19059	157	6	batch	batch	NOUN
bracis-19059	157	7	we	we	PRON
bracis-19059	157	8	use	use	VERB
bracis-19059	157	9	a	a	DET
bracis-19059	157	10	browser	browser	NOUN
bracis-19059	157	11	plugin	plugin	NOUN
bracis-19059	157	12	called	call	VERB
bracis-19059	157	13	imacros	imacro	NOUN
bracis-19059	157	14	.	.	PUNCT
bracis-19059	158	1	imacros	imacros	PROPN
bracis-19059	158	2	is	be	AUX
bracis-19059	158	3	a	a	DET
bracis-19059	158	4	scripting	scripting	NOUN
bracis-19059	158	5	language	language	NOUN
bracis-19059	158	6	that	that	PRON
bracis-19059	158	7	allows	allow	VERB
bracis-19059	158	8	users	user	NOUN
bracis-19059	158	9	to	to	PART
bracis-19059	158	10	simulate	simulate	VERB
bracis-19059	158	11	online	online	ADJ
bracis-19059	158	12	activities	activity	NOUN
bracis-19059	158	13	for	for	ADP
bracis-19059	158	14	filling	fill	VERB
bracis-19059	158	15	out	out	ADP
bracis-19059	158	16	forms	form	NOUN
bracis-19059	158	17	,	,	PUNCT
bracis-19059	158	18	uploading	uploading	NOUN
bracis-19059	158	19	and	and	CCONJ
bracis-19059	158	20	downloading	download	VERB
bracis-19059	158	21	images	image	NOUN
bracis-19059	158	22	and	and	CCONJ
bracis-19059	158	23	files	file	NOUN
bracis-19059	158	24	,	,	PUNCT
bracis-19059	158	25	or	or	CCONJ
bracis-19059	158	26	even	even	ADV
bracis-19059	158	27	importing	import	VERB
bracis-19059	158	28	and	and	CCONJ
bracis-19059	158	29	exporting	export	VERB
bracis-19059	158	30	information	information	NOUN
bracis-19059	158	31	from	from	ADP
bracis-19059	158	32	databases	database	NOUN
bracis-19059	158	33	,	,	PUNCT
bracis-19059	158	34	csv	csv	ADJ
bracis-19059	158	35	files	file	NOUN
bracis-19059	158	36	,	,	PUNCT
bracis-19059	158	37	xml	xml	NOUN
bracis-19059	158	38	files	file	NOUN
bracis-19059	158	39	,	,	PUNCT
bracis-19059	158	40	among	among	ADP
bracis-19059	158	41	others	other	NOUN
bracis-19059	158	42	.	.	PUNCT
bracis-19059	159	1	popmusic	popmusic	ADJ
bracis-19059	159	2	is	be	AUX
bracis-19059	159	3	different	different	ADJ
bracis-19059	159	4	of	of	ADP
bracis-19059	159	5	the	the	DET
bracis-19059	159	6	other	other	ADJ
bracis-19059	159	7	tools	tool	NOUN
bracis-19059	159	8	since	since	SCONJ
bracis-19059	159	9	it	it	PRON
bracis-19059	159	10	allows	allow	VERB
bracis-19059	159	11	the	the	DET
bracis-19059	159	12	user	user	NOUN
bracis-19059	159	13	to	to	PART
bracis-19059	159	14	inform	inform	VERB
bracis-19059	159	15	the	the	DET
bracis-19059	159	16	pdb	pdb	PROPN
bracis-19059	159	17	code	code	NOUN
bracis-19059	159	18	for	for	ADP
bracis-19059	159	19	each	each	PRON
bracis-19059	159	20	of	of	ADP
bracis-19059	159	21	the	the	DET
bracis-19059	159	22	151	151	NUM
bracis-19059	159	23	proteins	protein	NOUN
bracis-19059	159	24	of	of	ADP
bracis-19059	159	25	ds3904	ds3904	PROPN
bracis-19059	159	26	(	(	PUNCT
bracis-19059	159	27	and	and	CCONJ
bracis-19059	159	28	their	their	PRON
bracis-19059	159	29	specific	specific	ADJ
bracis-19059	159	30	mutation	mutation	NOUN
bracis-19059	159	31	positions	position	NOUN
bracis-19059	159	32	)	)	PUNCT
bracis-19059	159	33	in	in	ADP
bracis-19059	159	34	a	a	DET
bracis-19059	159	35	list	list	NOUN
bracis-19059	159	36	.	.	PUNCT
bracis-19059	160	1	the	the	DET
bracis-19059	160	2	results	result	NOUN
bracis-19059	160	3	were	be	AUX
bracis-19059	160	4	properly	properly	ADV
bracis-19059	160	5	stored	store	VERB
bracis-19059	160	6	in	in	ADP
bracis-19059	160	7	a	a	DET
bracis-19059	160	8	local	local	ADJ
bracis-19059	160	9	database	database	NOUN
bracis-19059	160	10	generating	generate	VERB
bracis-19059	160	11	our	our	PRON
bracis-19059	160	12	meta	meta	ADJ
bracis-19059	160	13	data	datum	NOUN
bracis-19059	160	14	(	(	PUNCT
bracis-19059	160	15	fig	fig	NOUN
bracis-19059	160	16	.	.	PUNCT
bracis-19059	160	17	 	 	SPACE
bracis-19059	160	18	2(b	2(b	NUM
bracis-19059	160	19	)	)	PUNCT
bracis-19059	160	20	)	)	PUNCT
bracis-19059	160	21	where	where	SCONJ
bracis-19059	160	22	we	we	PRON
bracis-19059	160	23	have	have	VERB
bracis-19059	160	24	as	as	ADP
bracis-19059	160	25	predictive	predictive	ADJ
bracis-19059	160	26	attributes	attribute	VERB
bracis-19059	160	27	the	the	DET
bracis-19059	160	28	predicted	predict	VERB
bracis-19059	160	29	\(\vardelta	\(\vardelta	NOUN
bracis-19059	160	30	\vardelta	\vardelta	NOUN
bracis-19059	160	31	\)g	\)g	PUNCT
bracis-19059	160	32	by	by	ADP
bracis-19059	160	33	the	the	DET
bracis-19059	160	34	tools	tool	NOUN
bracis-19059	160	35	and	and	CCONJ
bracis-19059	160	36	as	as	SCONJ
bracis-19059	160	37	target	target	NOUN
bracis-19059	160	38	attribut	attribut	NOUN
bracis-19059	160	39	the	the	DET
bracis-19059	160	40	experimental	experimental	ADJ
bracis-19059	160	41	\(\vardelta	\(\vardelta	NOUN
bracis-19059	160	42	\vardelta	\vardelta	NOUN
bracis-19059	160	43	\)g	\)g	PRON
bracis-19059	160	44	discretized	discretize	VERB
bracis-19059	160	45	as	as	ADP
bracis-19059	160	46	destabilizing	destabilizing	ADJ
bracis-19059	160	47	(	(	PUNCT
bracis-19059	160	48	\(\vardelta	\(\vardelta	X
bracis-19059	160	49	\vardelta	\vardelta	NOUN
bracis-19059	160	50	g	g	NOUN
bracis-19059	160	51	<	<	X
bracis-19059	160	52	0\	0\	PROPN
bracis-19059	160	53	)	)	PUNCT
bracis-19059	160	54	)	)	PUNCT
bracis-19059	160	55	or	or	CCONJ
bracis-19059	160	56	stabilizing	stabilize	VERB
bracis-19059	160	57	(	(	PUNCT
bracis-19059	160	58	\(\vardelta	\(\vardelta	X
bracis-19059	160	59	\vardelta	\vardelta	NOUN
bracis-19059	160	60	g	g	PROPN
bracis-19059	160	61	\ge	\ge	PROPN
bracis-19059	160	62	0\	0\	PROPN
bracis-19059	160	63	)	)	PUNCT
bracis-19059	160	64	)	)	PUNCT
bracis-19059	160	65	.	.	PUNCT
bracis-19059	161	1	fig	fig	NOUN
bracis-19059	161	2	.	.	PUNCT
bracis-19059	162	1	2	2	NUM
bracis-19059	162	2	.	.	X
bracis-19059	162	3	part	part	NOUN
bracis-19059	162	4	of	of	ADP
bracis-19059	162	5	input	input	NOUN
bracis-19059	162	6	data	datum	NOUN
bracis-19059	162	7	.	.	PUNCT
bracis-19059	163	1	(	(	PUNCT
bracis-19059	163	2	a	a	X
bracis-19059	163	3	)	)	PUNCT
bracis-19059	163	4	ds3904	ds3904	PROPN
bracis-19059	163	5	(	(	PUNCT
bracis-19059	163	6	b	b	X
bracis-19059	163	7	)	)	PUNCT
bracis-19059	163	8	meta	meta	PROPN
bracis-19059	163	9	data	datum	NOUN
bracis-19059	163	10	.	.	PUNCT
bracis-19059	164	1	full	full	ADJ
bracis-19059	164	2	size	size	NOUN
bracis-19059	164	3	image	image	NOUN
bracis-19059	164	4	4.3	4.3	NUM
bracis-19059	164	5	ensemble	ensemble	ADJ
bracis-19059	164	6	learning	learning	NOUN
bracis-19059	164	7	stacking	stack	VERB
bracis-19059	164	8	considering	consider	VERB
bracis-19059	164	9	as	as	ADP
bracis-19059	164	10	input	input	NOUN
bracis-19059	164	11	the	the	DET
bracis-19059	164	12	meta	meta	NOUN
bracis-19059	164	13	data	datum	NOUN
bracis-19059	164	14	generated	generate	VERB
bracis-19059	164	15	by	by	ADP
bracis-19059	164	16	heterogeneous	heterogeneous	ADJ
bracis-19059	164	17	predictive	predictive	ADJ
bracis-19059	164	18	tools	tool	NOUN
bracis-19059	164	19	in	in	ADP
bracis-19059	164	20	the	the	DET
bracis-19059	164	21	previous	previous	ADJ
bracis-19059	164	22	step	step	NOUN
bracis-19059	164	23	we	we	PRON
bracis-19059	164	24	performed	perform	VERB
bracis-19059	164	25	stacking	stack	VERB
bracis-19059	164	26	ensemble	ensemble	ADJ
bracis-19059	164	27	learning	learning	NOUN
bracis-19059	164	28	considering	consider	VERB
bracis-19059	164	29	as	as	ADP
bracis-19059	164	30	meta	meta	ADJ
bracis-19059	164	31	classifiers	classifier	NOUN
bracis-19059	164	32	:	:	PUNCT
bracis-19059	164	33	random	random	ADJ
bracis-19059	164	34	forest	forest	NOUN
bracis-19059	164	35	(	(	PUNCT
bracis-19059	164	36	rf	rf	NOUN
bracis-19059	164	37	)	)	PUNCT
bracis-19059	164	38	,	,	PUNCT
bracis-19059	164	39	decision	decision	NOUN
bracis-19059	164	40	trees	tree	NOUN
bracis-19059	164	41	(	(	PUNCT
bracis-19059	164	42	dt	dt	PROPN
bracis-19059	164	43	)	)	PUNCT
bracis-19059	164	44	,	,	PUNCT
bracis-19059	164	45	support	support	VERB
bracis-19059	164	46	vector	vector	NOUN
bracis-19059	164	47	machines	machine	NOUN
bracis-19059	164	48	(	(	PUNCT
bracis-19059	164	49	svm	svm	PROPN
bracis-19059	164	50	)	)	PUNCT
bracis-19059	164	51	,	,	PUNCT
bracis-19059	164	52	multilayer	multilayer	PROPN
bracis-19059	164	53	perceptron	perceptron	PROPN
bracis-19059	164	54	radial	radial	ADJ
bracis-19059	164	55	basis	basis	NOUN
bracis-19059	164	56	function	function	NOUN
bracis-19059	164	57	(	(	PUNCT
bracis-19059	164	58	mlp	mlp	NOUN
bracis-19059	164	59	)	)	PUNCT
bracis-19059	164	60	and	and	CCONJ
bracis-19059	164	61	naive	naive	ADJ
bracis-19059	164	62	bayes	bayes	NOUN
bracis-19059	164	63	(	(	PUNCT
bracis-19059	164	64	nb	nb	NOUN
bracis-19059	164	65	)	)	PUNCT
bracis-19059	164	66	.	.	PUNCT
bracis-19059	165	1	the	the	DET
bracis-19059	165	2	parameters	parameter	NOUN
bracis-19059	165	3	of	of	ADP
bracis-19059	165	4	these	these	DET
bracis-19059	165	5	algorithms	algorithm	NOUN
bracis-19059	165	6	were	be	AUX
bracis-19059	165	7	set	set	VERB
bracis-19059	165	8	as	as	ADP
bracis-19059	165	9	default	default	NOUN
bracis-19059	165	10	values	value	NOUN
bracis-19059	165	11	:	:	PUNCT
bracis-19059	165	12	dt	dt	X
bracis-19059	165	13	(	(	PUNCT
bracis-19059	165	14	maxdepth	maxdepth	NOUN
bracis-19059	165	15	=	=	SYM
bracis-19059	165	16	unlimited	unlimited	ADJ
bracis-19059	165	17	;	;	PUNCT
bracis-19059	165	18	numfeatures	numfeature	NOUN
bracis-19059	165	19	=	=	SYM
bracis-19059	165	20	unlimited	unlimited	ADJ
bracis-19059	165	21	;	;	PUNCT
bracis-19059	165	22	numtrees	numtree	NOUN
bracis-19059	165	23	=	=	SYM
bracis-19059	165	24	100	100	NUM
bracis-19059	165	25	)	)	PUNCT
bracis-19059	165	26	,	,	PUNCT
bracis-19059	165	27	svm	svm	PROPN
bracis-19059	165	28	(	(	PUNCT
bracis-19059	165	29	degree	degree	NOUN
bracis-19059	165	30	of	of	ADP
bracis-19059	165	31	the	the	DET
bracis-19059	165	32	kernel	kernel	NOUN
bracis-19059	165	33	=	=	SYM
bracis-19059	165	34	3	3	NUM
bracis-19059	165	35	;	;	PUNCT
bracis-19059	165	36	kernel	kernel	NOUN
bracis-19059	165	37	type	type	NOUN
bracis-19059	165	38	=	=	NOUN
bracis-19059	165	39	radial	radial	NOUN
bracis-19059	165	40	;	;	PUNCT
bracis-19059	165	41	eps	eps	X
bracis-19059	165	42	=	=	NOUN
bracis-19059	165	43	0.001	0.001	NUM
bracis-19059	165	44	)	)	PUNCT
bracis-19059	165	45	,	,	PUNCT
bracis-19059	165	46	mlp	mlp	PROPN
bracis-19059	165	47	(	(	PUNCT
bracis-19059	165	48	autobuild	autobuild	NOUN
bracis-19059	165	49	=	=	PUNCT
bracis-19059	165	50	true	true	ADJ
bracis-19059	165	51	;	;	PUNCT
bracis-19059	165	52	decay	decay	NOUN
bracis-19059	165	53	=	=	SYM
bracis-19059	165	54	false	false	ADJ
bracis-19059	165	55	;	;	PUNCT
bracis-19059	165	56	hiddenlayers	hiddenlayer	NOUN
bracis-19059	165	57	=	=	PUNCT
bracis-19059	165	58	‘	'	PUNCT
bracis-19059	165	59	a	a	X
bracis-19059	165	60	’	'	PUNCT
bracis-19059	165	61	;	;	PUNCT
bracis-19059	165	62	learningrate	learningrate	NOUN
bracis-19059	165	63	=	=	NUM
bracis-19059	165	64	0.3	0.3	NUM
bracis-19059	165	65	;	;	PUNCT
bracis-19059	165	66	momentum	momentum	NOUN
bracis-19059	165	67	=	=	SYM
bracis-19059	165	68	0.2	0.2	NUM
bracis-19059	165	69	;	;	PUNCT
bracis-19059	165	70	validationthreshold	validationthreshold	ADJ
bracis-19059	165	71	=	=	NOUN
bracis-19059	165	72	20	20	NUM
bracis-19059	165	73	)	)	PUNCT
bracis-19059	165	74	and	and	CCONJ
bracis-19059	165	75	nb	nb	INTJ
bracis-19059	165	76	(	(	PUNCT
bracis-19059	165	77	usekernelestimator	usekernelestimator	NOUN
bracis-19059	165	78	=	=	PUNCT
bracis-19059	165	79	false	false	ADJ
bracis-19059	165	80	and	and	CCONJ
bracis-19059	165	81	usesuperviseddiscretization	usesuperviseddiscretization	NOUN
bracis-19059	165	82	=	=	SYM
bracis-19059	165	83	false	false	ADJ
bracis-19059	165	84	)	)	PUNCT
bracis-19059	165	85	.	.	PUNCT
bracis-19059	166	1	we	we	PRON
bracis-19059	166	2	evaluate	evaluate	VERB
bracis-19059	166	3	all	all	DET
bracis-19059	166	4	the	the	DET
bracis-19059	166	5	generated	generate	VERB
bracis-19059	166	6	ensemble	ensemble	ADJ
bracis-19059	166	7	models	model	NOUN
bracis-19059	166	8	using	use	VERB
bracis-19059	166	9	accuracy	accuracy	NOUN
bracis-19059	166	10	,	,	PUNCT
bracis-19059	166	11	precision	precision	NOUN
bracis-19059	166	12	,	,	PUNCT
bracis-19059	166	13	recall	recall	NOUN
bracis-19059	166	14	and	and	CCONJ
bracis-19059	166	15	f	f	NOUN
bracis-19059	166	16	-	-	PUNCT
bracis-19059	166	17	measure	measure	NOUN
bracis-19059	166	18	.	.	PUNCT
bracis-19059	167	1	4.4	4.4	NUM
bracis-19059	167	2	ensemble	ensemble	ADJ
bracis-19059	167	3	learning	learning	NOUN
bracis-19059	167	4	bagging	bagging	NOUN
bracis-19059	167	5	/	/	SYM
bracis-19059	167	6	boosting	boost	VERB
bracis-19059	167	7	in	in	ADP
bracis-19059	167	8	order	order	NOUN
bracis-19059	167	9	to	to	PART
bracis-19059	167	10	evaluate	evaluate	VERB
bracis-19059	167	11	the	the	DET
bracis-19059	167	12	impact	impact	NOUN
bracis-19059	167	13	of	of	ADP
bracis-19059	167	14	ensemble	ensemble	ADJ
bracis-19059	167	15	learning	learning	NOUN
bracis-19059	167	16	not	not	PART
bracis-19059	167	17	only	only	ADV
bracis-19059	167	18	with	with	ADP
bracis-19059	167	19	stacking	stack	VERB
bracis-19059	167	20	configuration	configuration	NOUN
bracis-19059	167	21	we	we	PRON
bracis-19059	167	22	decided	decide	VERB
bracis-19059	167	23	to	to	PART
bracis-19059	167	24	also	also	ADV
bracis-19059	167	25	apply	apply	VERB
bracis-19059	167	26	bagging	bagging	NOUN
bracis-19059	167	27	and	and	CCONJ
bracis-19059	167	28	boosting	boost	VERB
bracis-19059	167	29	.	.	PUNCT
bracis-19059	168	1	we	we	PRON
bracis-19059	168	2	have	have	AUX
bracis-19059	168	3	performed	perform	VERB
bracis-19059	168	4	different	different	ADJ
bracis-19059	168	5	configurations	configuration	NOUN
bracis-19059	168	6	for	for	ADP
bracis-19059	168	7	this	this	DET
bracis-19059	168	8	ensemble	ensemble	ADJ
bracis-19059	168	9	experiments	experiment	NOUN
bracis-19059	168	10	:	:	PUNCT
bracis-19059	168	11	bagging	bagging	NOUN
bracis-19059	168	12	and	and	CCONJ
bracis-19059	168	13	boosting	boost	VERB
bracis-19059	168	14	.	.	PUNCT
bracis-19059	169	1	the	the	DET
bracis-19059	169	2	parameters	parameter	NOUN
bracis-19059	169	3	of	of	ADP
bracis-19059	169	4	these	these	DET
bracis-19059	169	5	algorithms	algorithm	NOUN
bracis-19059	169	6	were	be	AUX
bracis-19059	169	7	set	set	VERB
bracis-19059	169	8	as	as	ADP
bracis-19059	169	9	default	default	NOUN
bracis-19059	169	10	values	value	NOUN
bracis-19059	169	11	:	:	PUNCT
bracis-19059	169	12	bagging	bag	VERB
bracis-19059	169	13	(	(	PUNCT
bracis-19059	169	14	bagsizepercent	bagsizepercent	NOUN
bracis-19059	169	15	=	=	NOUN
bracis-19059	169	16	100	100	NUM
bracis-19059	169	17	;	;	PUNCT
bracis-19059	169	18	calcoutofbag	calcoutofbag	NOUN
bracis-19059	169	19	=	=	SYM
bracis-19059	169	20	false	false	ADJ
bracis-19059	169	21	;	;	PUNCT
bracis-19059	169	22	classifiers	classifier	NOUN
bracis-19059	169	23	=	=	SYM
bracis-19059	169	24	svm	svm	PROPN
bracis-19059	169	25	,	,	PUNCT
bracis-19059	169	26	dt	dt	PROPN
bracis-19059	169	27	,	,	PUNCT
bracis-19059	169	28	mlp	mlp	PROPN
bracis-19059	169	29	and	and	CCONJ
bracis-19059	169	30	nv	nv	PROPN
bracis-19059	169	31	same	same	ADJ
bracis-19059	169	32	parameters	parameter	NOUN
bracis-19059	169	33	used	use	VERB
bracis-19059	169	34	in	in	ADP
bracis-19059	169	35	stacking	stacking	NOUN
bracis-19059	169	36	;	;	PUNCT
bracis-19059	169	37	numiterations	numiteration	NOUN
bracis-19059	169	38	=	=	SYM
bracis-19059	169	39	10	10	NUM
bracis-19059	169	40	)	)	PUNCT
bracis-19059	169	41	,	,	PUNCT
bracis-19059	169	42	boosting	boost	VERB
bracis-19059	169	43	(	(	PUNCT
bracis-19059	169	44	numiterations	numiteration	NOUN
bracis-19059	169	45	=	=	SYM
bracis-19059	169	46	10	10	NUM
bracis-19059	169	47	;	;	PUNCT
bracis-19059	169	48	classifiers	classifier	NOUN
bracis-19059	169	49	=	=	SYM
bracis-19059	169	50	svm	svm	PROPN
bracis-19059	169	51	,	,	PUNCT
bracis-19059	169	52	dt	dt	PROPN
bracis-19059	169	53	,	,	PUNCT
bracis-19059	169	54	mlp	mlp	PROPN
bracis-19059	169	55	and	and	CCONJ
bracis-19059	169	56	nv	nv	PROPN
bracis-19059	169	57	same	same	ADJ
bracis-19059	169	58	parameters	parameter	NOUN
bracis-19059	169	59	used	use	VERB
bracis-19059	169	60	in	in	ADP
bracis-19059	169	61	stacking	stacking	NOUN
bracis-19059	169	62	;	;	PUNCT
bracis-19059	169	63	useresampling	useresample	VERB
bracis-19059	169	64	=	=	VERB
bracis-19059	169	65	false	false	ADJ
bracis-19059	169	66	;	;	PUNCT
bracis-19059	169	67	weightthreshold	weightthreshold	ADJ
bracis-19059	169	68	=	=	SYM
bracis-19059	169	69	100	100	NUM
bracis-19059	169	70	)	)	PUNCT
bracis-19059	169	71	.	.	PUNCT
bracis-19059	170	1	the	the	DET
bracis-19059	170	2	stacking	stacking	NOUN
bracis-19059	170	3	,	,	PUNCT
bracis-19059	170	4	bagging	bagging	NOUN
bracis-19059	170	5	and	and	CCONJ
bracis-19059	170	6	boosting	boost	VERB
bracis-19059	170	7	ensemble	ensemble	ADJ
bracis-19059	170	8	learning	learning	NOUN
bracis-19059	170	9	algorithms	algorithm	NOUN
bracis-19059	170	10	were	be	AUX
bracis-19059	170	11	performed	perform	VERB
bracis-19059	170	12	using	use	VERB
bracis-19059	170	13	weka	weka	PROPN
bracis-19059	170	14	3.8	3.8	NUM
bracis-19059	171	1	[	[	X
bracis-19059	171	2	24	24	NUM
bracis-19059	171	3	]	]	PUNCT
bracis-19059	171	4	.	.	PUNCT
bracis-19059	172	1	5	5	NUM
bracis-19059	172	2	results	result	NOUN
bracis-19059	172	3	and	and	CCONJ
bracis-19059	172	4	 	 	SPACE
bracis-19059	172	5	discussion	discussion	NOUN
bracis-19059	172	6	to	to	PART
bracis-19059	172	7	evaluate	evaluate	VERB
bracis-19059	172	8	our	our	PRON
bracis-19059	172	9	proposed	propose	VERB
bracis-19059	172	10	methodology	methodology	NOUN
bracis-19059	172	11	of	of	ADP
bracis-19059	172	12	ensemble	ensemble	ADJ
bracis-19059	172	13	learning	learning	NOUN
bracis-19059	172	14	for	for	ADP
bracis-19059	172	15	this	this	DET
bracis-19059	172	16	problem	problem	NOUN
bracis-19059	172	17	we	we	PRON
bracis-19059	172	18	performed	perform	VERB
bracis-19059	172	19	two	two	NUM
bracis-19059	172	20	experiments	experiment	NOUN
bracis-19059	172	21	:	:	PUNCT
bracis-19059	172	22	experiment	experiment	NOUN
bracis-19059	172	23	1	1	NUM
bracis-19059	172	24	considers	consider	VERB
bracis-19059	172	25	a	a	DET
bracis-19059	172	26	balanced	balanced	ADJ
bracis-19059	172	27	training	training	NOUN
bracis-19059	172	28	dataset	dataset	NOUN
bracis-19059	172	29	from	from	ADP
bracis-19059	172	30	where	where	SCONJ
bracis-19059	172	31	500	500	NUM
bracis-19059	172	32	random	random	ADJ
bracis-19059	172	33	instances	instance	NOUN
bracis-19059	172	34	where	where	SCONJ
bracis-19059	172	35	selected	select	VERB
bracis-19059	172	36	from	from	ADP
bracis-19059	172	37	ds3904	ds3904	PROPN
bracis-19059	172	38	for	for	ADP
bracis-19059	172	39	each	each	DET
bracis-19059	172	40	target	target	NOUN
bracis-19059	172	41	value	value	NOUN
bracis-19059	172	42	stabilizing	stabilizing	NOUN
bracis-19059	172	43	and	and	CCONJ
bracis-19059	172	44	destabilizing	destabilizing	ADJ
bracis-19059	172	45	;	;	PUNCT
bracis-19059	172	46	in	in	ADP
bracis-19059	172	47	experiment	experiment	NOUN
bracis-19059	172	48	2	2	NUM
bracis-19059	172	49	we	we	PRON
bracis-19059	172	50	divided	divide	VERB
bracis-19059	172	51	ds3904	ds3904	PROPN
bracis-19059	172	52	in	in	ADP
bracis-19059	172	53	\(70\%\	\(70\%\	NOUN
bracis-19059	172	54	)	)	PUNCT
bracis-19059	172	55	(	(	PUNCT
bracis-19059	172	56	training	training	NOUN
bracis-19059	172	57	)	)	PUNCT
bracis-19059	172	58	and	and	CCONJ
bracis-19059	172	59	\(30\%\	\(30\%\	X
bracis-19059	172	60	)	)	PUNCT
bracis-19059	172	61	(	(	PUNCT
bracis-19059	172	62	testing	testing	NOUN
bracis-19059	172	63	)	)	PUNCT
bracis-19059	172	64	,	,	PUNCT
bracis-19059	172	65	and	and	CCONJ
bracis-19059	172	66	we	we	PRON
bracis-19059	172	67	have	have	AUX
bracis-19059	172	68	not	not	PART
bracis-19059	172	69	balanced	balance	VERB
bracis-19059	172	70	training	training	NOUN
bracis-19059	172	71	/	/	SYM
bracis-19059	172	72	testing	testing	NOUN
bracis-19059	172	73	datasets	dataset	NOUN
bracis-19059	172	74	.	.	PUNCT
bracis-19059	173	1	table	table	NOUN
bracis-19059	173	2	 	 	SPACE
bracis-19059	173	3	2	2	NUM
bracis-19059	173	4	describes	describe	VERB
bracis-19059	173	5	the	the	DET
bracis-19059	173	6	datasets	dataset	NOUN
bracis-19059	173	7	for	for	ADP
bracis-19059	173	8	experiments	experiment	NOUN
bracis-19059	173	9	1	1	NUM
bracis-19059	173	10	and	and	CCONJ
bracis-19059	173	11	2	2	NUM
bracis-19059	173	12	.	.	NOUN
bracis-19059	173	13	table	table	NOUN
bracis-19059	173	14	2	2	NUM
bracis-19059	173	15	.	.	PUNCT
bracis-19059	173	16	training	training	NOUN
bracis-19059	173	17	and	and	CCONJ
bracis-19059	173	18	testing	testing	NOUN
bracis-19059	173	19	datasets	dataset	NOUN
bracis-19059	173	20	for	for	ADP
bracis-19059	173	21	experiments	experiment	NOUN
bracis-19059	173	22	1	1	NUM
bracis-19059	173	23	and	and	CCONJ
bracis-19059	173	24	2.full	2.full	NUM
bracis-19059	173	25	size	size	NOUN
bracis-19059	173	26	table	table	NOUN
bracis-19059	173	27	5.1	5.1	NUM
bracis-19059	173	28	experiment	experiment	NOUN
bracis-19059	173	29	1	1	NUM
bracis-19059	173	30	:	:	PUNCT
bracis-19059	173	31	balanced	balanced	ADJ
bracis-19059	173	32	training	training	NOUN
bracis-19059	173	33	dataset	dataset	NOUN
bracis-19059	173	34	ds3904	ds3904	PROPN
bracis-19059	173	35	is	be	AUX
bracis-19059	173	36	unbalanced	unbalanced	ADJ
bracis-19059	173	37	according	accord	VERB
bracis-19059	173	38	to	to	ADP
bracis-19059	173	39	the	the	DET
bracis-19059	173	40	target	target	NOUN
bracis-19059	173	41	attribute	attribute	NOUN
bracis-19059	173	42	.	.	PUNCT
bracis-19059	174	1	although	although	SCONJ
bracis-19059	174	2	it	it	PRON
bracis-19059	174	3	is	be	AUX
bracis-19059	174	4	common	common	ADJ
bracis-19059	174	5	in	in	ADP
bracis-19059	174	6	real	real	ADJ
bracis-19059	174	7	datasets	dataset	NOUN
bracis-19059	174	8	can	can	AUX
bracis-19059	174	9	cause	cause	VERB
bracis-19059	174	10	some	some	DET
bracis-19059	174	11	problems	problem	NOUN
bracis-19059	174	12	in	in	ADP
bracis-19059	174	13	generating	generate	VERB
bracis-19059	174	14	predictive	predictive	ADJ
bracis-19059	174	15	models	model	NOUN
bracis-19059	174	16	as	as	ADP
bracis-19059	174	17	being	be	AUX
bracis-19059	174	18	highly	highly	ADV
bracis-19059	174	19	specialized	specialized	ADJ
bracis-19059	174	20	(	(	PUNCT
bracis-19059	174	21	specially	specially	ADV
bracis-19059	174	22	to	to	PART
bracis-19059	174	23	detect	detect	VERB
bracis-19059	174	24	the	the	DET
bracis-19059	174	25	rare	rare	ADJ
bracis-19059	174	26	class	class	NOUN
bracis-19059	174	27	)	)	PUNCT
bracis-19059	174	28	or	or	CCONJ
bracis-19059	174	29	susceptible	susceptible	ADJ
bracis-19059	174	30	to	to	ADP
bracis-19059	174	31	presence	presence	NOUN
bracis-19059	174	32	of	of	ADP
bracis-19059	174	33	noise	noise	NOUN
bracis-19059	174	34	[	[	X
bracis-19059	174	35	22	22	NUM
bracis-19059	174	36	]	]	PUNCT
bracis-19059	174	37	.	.	PUNCT
bracis-19059	175	1	thus	thus	ADV
bracis-19059	175	2	,	,	PUNCT
bracis-19059	175	3	we	we	PRON
bracis-19059	175	4	decided	decide	VERB
bracis-19059	175	5	to	to	PART
bracis-19059	175	6	train	train	VERB
bracis-19059	175	7	the	the	DET
bracis-19059	175	8	stacking	stacking	NOUN
bracis-19059	175	9	and	and	CCONJ
bracis-19059	175	10	bagging	bagging	NOUN
bracis-19059	175	11	/	/	SYM
bracis-19059	175	12	boosting	boost	VERB
bracis-19059	175	13	ensemble	ensemble	ADJ
bracis-19059	175	14	models	model	NOUN
bracis-19059	175	15	in	in	ADP
bracis-19059	175	16	experiment	experiment	NOUN
bracis-19059	175	17	1	1	NUM
bracis-19059	175	18	with	with	ADP
bracis-19059	175	19	500	500	NUM
bracis-19059	175	20	random	random	ADJ
bracis-19059	175	21	instances	instance	NOUN
bracis-19059	175	22	of	of	ADP
bracis-19059	175	23	each	each	DET
bracis-19059	175	24	class	class	NOUN
bracis-19059	175	25	,	,	PUNCT
bracis-19059	175	26	totaling	total	VERB
bracis-19059	175	27	1000	1000	NUM
bracis-19059	175	28	instances	instance	NOUN
bracis-19059	175	29	for	for	ADP
bracis-19059	175	30	training	training	NOUN
bracis-19059	175	31	.	.	PUNCT
bracis-19059	176	1	the	the	DET
bracis-19059	176	2	remaining	remain	VERB
bracis-19059	176	3	2904	2904	NUM
bracis-19059	176	4	instances	instance	NOUN
bracis-19059	176	5	are	be	AUX
bracis-19059	176	6	part	part	NOUN
bracis-19059	176	7	of	of	ADP
bracis-19059	176	8	the	the	DET
bracis-19059	176	9	test	test	NOUN
bracis-19059	176	10	set	set	NOUN
bracis-19059	176	11	.	.	PUNCT
bracis-19059	177	1	in	in	ADP
bracis-19059	177	2	order	order	NOUN
bracis-19059	177	3	to	to	PART
bracis-19059	177	4	compare	compare	VERB
bracis-19059	177	5	the	the	DET
bracis-19059	177	6	results	result	NOUN
bracis-19059	177	7	of	of	ADP
bracis-19059	177	8	the	the	DET
bracis-19059	177	9	generated	generate	VERB
bracis-19059	177	10	ensemble	ensemble	ADJ
bracis-19059	177	11	models	model	NOUN
bracis-19059	177	12	with	with	ADP
bracis-19059	177	13	the	the	DET
bracis-19059	177	14	individual	individual	ADJ
bracis-19059	177	15	tools	tool	NOUN
bracis-19059	177	16	we	we	PRON
bracis-19059	177	17	calculated	calculate	VERB
bracis-19059	177	18	the	the	DET
bracis-19059	177	19	metrics	metric	NOUN
bracis-19059	177	20	accuracy	accuracy	NOUN
bracis-19059	177	21	,	,	PUNCT
bracis-19059	177	22	precision	precision	NOUN
bracis-19059	177	23	,	,	PUNCT
bracis-19059	177	24	recall	recall	NOUN
bracis-19059	177	25	and	and	CCONJ
bracis-19059	177	26	f	f	NOUN
bracis-19059	177	27	-	-	PUNCT
bracis-19059	177	28	measure	measure	NOUN
bracis-19059	177	29	for	for	ADP
bracis-19059	177	30	the	the	DET
bracis-19059	177	31	test	test	NOUN
bracis-19059	177	32	set	set	VERB
bracis-19059	177	33	for	for	ADP
bracis-19059	177	34	all	all	PRON
bracis-19059	177	35	.	.	PUNCT
bracis-19059	178	1	first	first	ADV
bracis-19059	178	2	,	,	PUNCT
bracis-19059	178	3	we	we	PRON
bracis-19059	178	4	evaluate	evaluate	VERB
bracis-19059	178	5	the	the	DET
bracis-19059	178	6	individual	individual	ADJ
bracis-19059	178	7	tools	tool	NOUN
bracis-19059	178	8	considering	consider	VERB
bracis-19059	178	9	the	the	DET
bracis-19059	178	10	test	test	NOUN
bracis-19059	178	11	set	set	VERB
bracis-19059	178	12	with	with	ADP
bracis-19059	178	13	2904	2904	NUM
bracis-19059	178	14	instances	instance	NOUN
bracis-19059	178	15	(	(	PUNCT
bracis-19059	178	16	see	see	VERB
bracis-19059	178	17	table	table	NOUN
bracis-19059	178	18	 	 	SPACE
bracis-19059	178	19	2)and	2)and	NUM
bracis-19059	178	20	comparing	compare	VERB
bracis-19059	178	21	the	the	DET
bracis-19059	178	22	predicted	predict	VERB
bracis-19059	178	23	\(\vardelta	\(\vardelta	NOUN
bracis-19059	178	24	\vardelta	\vardelta	NOUN
bracis-19059	178	25	\)g	\)g	NOUN
bracis-19059	178	26	with	with	ADP
bracis-19059	178	27	the	the	DET
bracis-19059	178	28	experimental	experimental	ADJ
bracis-19059	178	29	value	value	NOUN
bracis-19059	178	30	from	from	ADP
bracis-19059	178	31	protherm	protherm	NOUN
bracis-19059	178	32	(	(	PUNCT
bracis-19059	178	33	table	table	NOUN
bracis-19059	178	34	 	 	SPACE
bracis-19059	178	35	3	3	NUM
bracis-19059	178	36	)	)	PUNCT
bracis-19059	178	37	.	.	PUNCT
bracis-19059	179	1	we	we	PRON
bracis-19059	179	2	can	can	AUX
bracis-19059	179	3	observe	observe	VERB
bracis-19059	179	4	that	that	SCONJ
bracis-19059	179	5	all	all	DET
bracis-19059	179	6	tools	tool	NOUN
bracis-19059	179	7	obtained	obtain	VERB
bracis-19059	179	8	good	good	ADJ
bracis-19059	179	9	accuracy	accuracy	NOUN
bracis-19059	179	10	values	value	NOUN
bracis-19059	179	11	but	but	CCONJ
bracis-19059	179	12	with	with	ADP
bracis-19059	179	13	low	low	ADJ
bracis-19059	179	14	values	value	NOUN
bracis-19059	179	15	for	for	ADP
bracis-19059	179	16	precision	precision	NOUN
bracis-19059	179	17	.	.	PUNCT
bracis-19059	180	1	it	it	PRON
bracis-19059	180	2	is	be	AUX
bracis-19059	180	3	important	important	ADJ
bracis-19059	180	4	to	to	PART
bracis-19059	180	5	mention	mention	VERB
bracis-19059	180	6	that	that	SCONJ
bracis-19059	180	7	our	our	PRON
bracis-19059	180	8	test	test	NOUN
bracis-19059	180	9	set	set	VERB
bracis-19059	180	10	probably	probably	ADV
bracis-19059	180	11	was	be	AUX
bracis-19059	180	12	used	use	VERB
bracis-19059	180	13	by	by	ADP
bracis-19059	180	14	the	the	DET
bracis-19059	180	15	tools	tool	NOUN
bracis-19059	180	16	to	to	PART
bracis-19059	180	17	train	train	VERB
bracis-19059	180	18	their	their	PRON
bracis-19059	180	19	models	model	NOUN
bracis-19059	180	20	.	.	PUNCT
bracis-19059	181	1	table	table	NOUN
bracis-19059	181	2	3	3	NUM
bracis-19059	181	3	.	.	PUNCT
bracis-19059	182	1	evaluation	evaluation	NOUN
bracis-19059	182	2	of	of	ADP
bracis-19059	182	3	individual	individual	ADJ
bracis-19059	182	4	tools	tool	NOUN
bracis-19059	182	5	in	in	ADP
bracis-19059	182	6	experiment	experiment	NOUN
bracis-19059	182	7	1.full	1.full	NUM
bracis-19059	182	8	size	size	NOUN
bracis-19059	182	9	table	table	NOUN
bracis-19059	182	10	both	both	PRON
bracis-19059	182	11	stacking	stack	VERB
bracis-19059	182	12	(	(	PUNCT
bracis-19059	182	13	table	table	NOUN
bracis-19059	182	14	 	 	SPACE
bracis-19059	182	15	4	4	NUM
bracis-19059	182	16	)	)	PUNCT
bracis-19059	182	17	,	,	PUNCT
bracis-19059	182	18	and	and	CCONJ
bracis-19059	182	19	bagging	bag	VERB
bracis-19059	182	20	/	/	SYM
bracis-19059	182	21	boosting	boost	VERB
bracis-19059	182	22	ensemble	ensemble	ADJ
bracis-19059	182	23	models	model	NOUN
bracis-19059	182	24	(	(	PUNCT
bracis-19059	182	25	table	table	NOUN
bracis-19059	182	26	 	 	SPACE
bracis-19059	182	27	5	5	NUM
bracis-19059	182	28	)	)	PUNCT
bracis-19059	182	29	,	,	PUNCT
bracis-19059	182	30	obtained	obtain	VERB
bracis-19059	182	31	good	good	ADJ
bracis-19059	182	32	values	value	NOUN
bracis-19059	182	33	of	of	ADP
bracis-19059	182	34	accuracy	accuracy	NOUN
bracis-19059	182	35	and	and	CCONJ
bracis-19059	182	36	precision	precision	NOUN
bracis-19059	182	37	.	.	PUNCT
bracis-19059	183	1	from	from	ADP
bracis-19059	183	2	these	these	DET
bracis-19059	183	3	results	result	NOUN
bracis-19059	183	4	,	,	PUNCT
bracis-19059	183	5	we	we	PRON
bracis-19059	183	6	can	can	AUX
bracis-19059	183	7	highlight	highlight	VERB
bracis-19059	183	8	svm	svm	PROPN
bracis-19059	183	9	,	,	PUNCT
bracis-19059	183	10	multilayer	multilayer	ADJ
bracis-19059	183	11	perceptron	perceptron	NOUN
bracis-19059	183	12	and	and	CCONJ
bracis-19059	183	13	random	random	ADJ
bracis-19059	183	14	forest	forest	NOUN
bracis-19059	183	15	close	close	ADJ
bracis-19059	183	16	to	to	ADP
bracis-19059	183	17	mcsm	mcsm	NOUN
bracis-19059	183	18	tool	tool	NOUN
bracis-19059	183	19	.	.	PUNCT
bracis-19059	184	1	from	from	ADP
bracis-19059	184	2	the	the	DET
bracis-19059	184	3	experiment	experiment	NOUN
bracis-19059	184	4	1	1	NUM
bracis-19059	184	5	results	result	NOUN
bracis-19059	184	6	we	we	PRON
bracis-19059	184	7	can	can	AUX
bracis-19059	184	8	notice	notice	VERB
bracis-19059	184	9	that	that	SCONJ
bracis-19059	184	10	better	well	ADJ
bracis-19059	184	11	precision	precision	NOUN
bracis-19059	184	12	measures	measure	NOUN
bracis-19059	184	13	were	be	AUX
bracis-19059	184	14	obtained	obtain	VERB
bracis-19059	184	15	if	if	SCONJ
bracis-19059	184	16	we	we	PRON
bracis-19059	184	17	compare	compare	VERB
bracis-19059	184	18	with	with	ADP
bracis-19059	184	19	individual	individual	ADJ
bracis-19059	184	20	tools	tool	NOUN
bracis-19059	184	21	.	.	PUNCT
bracis-19059	185	1	table	table	NOUN
bracis-19059	185	2	4	4	NUM
bracis-19059	185	3	.	.	PUNCT
bracis-19059	185	4	evaluation	evaluation	NOUN
bracis-19059	185	5	of	of	ADP
bracis-19059	185	6	stacking	stack	VERB
bracis-19059	185	7	ensemble	ensemble	ADJ
bracis-19059	185	8	in	in	ADP
bracis-19059	185	9	experiment	experiment	NOUN
bracis-19059	185	10	1.full	1.full	NUM
bracis-19059	185	11	size	size	NOUN
bracis-19059	185	12	table	table	NOUN
bracis-19059	185	13	table	table	NOUN
bracis-19059	185	14	5	5	NUM
bracis-19059	185	15	.	.	PUNCT
bracis-19059	185	16	evaluation	evaluation	NOUN
bracis-19059	185	17	of	of	ADP
bracis-19059	185	18	bagging	bagging	NOUN
bracis-19059	185	19	/	/	SYM
bracis-19059	185	20	boosting	boost	VERB
bracis-19059	185	21	in	in	ADP
bracis-19059	185	22	experiment	experiment	NOUN
bracis-19059	185	23	1.full	1.full	NUM
bracis-19059	185	24	size	size	NOUN
bracis-19059	185	25	table	table	NOUN
bracis-19059	185	26	the	the	DET
bracis-19059	185	27	predictions	prediction	NOUN
bracis-19059	185	28	about	about	ADP
bracis-19059	185	29	point	point	NOUN
bracis-19059	185	30	mutation	mutation	NOUN
bracis-19059	185	31	effects	effect	NOUN
bracis-19059	185	32	on	on	ADP
bracis-19059	185	33	protein	protein	NOUN
bracis-19059	185	34	structures	structure	NOUN
bracis-19059	185	35	are	be	AUX
bracis-19059	185	36	going	go	VERB
bracis-19059	185	37	to	to	PART
bracis-19059	185	38	be	be	AUX
bracis-19059	185	39	used	use	VERB
bracis-19059	185	40	in	in	ADP
bracis-19059	185	41	the	the	DET
bracis-19059	185	42	decision	decision	NOUN
bracis-19059	185	43	of	of	ADP
bracis-19059	185	44	generating	generate	VERB
bracis-19059	185	45	experimentally	experimentally	ADV
bracis-19059	185	46	some	some	DET
bracis-19059	185	47	proposed	propose	VERB
bracis-19059	185	48	protein	protein	NOUN
bracis-19059	185	49	mutations	mutation	NOUN
bracis-19059	185	50	,	,	PUNCT
bracis-19059	185	51	which	which	PRON
bracis-19059	185	52	is	be	AUX
bracis-19059	185	53	expensive	expensive	ADJ
bracis-19059	185	54	in	in	ADP
bracis-19059	185	55	terms	term	NOUN
bracis-19059	185	56	of	of	ADP
bracis-19059	185	57	time	time	NOUN
bracis-19059	185	58	and	and	CCONJ
bracis-19059	185	59	costs	cost	NOUN
bracis-19059	185	60	.	.	PUNCT
bracis-19059	186	1	considering	consider	VERB
bracis-19059	186	2	stabilizing	stabilize	VERB
bracis-19059	186	3	as	as	ADP
bracis-19059	186	4	a	a	DET
bracis-19059	186	5	positive	positive	ADJ
bracis-19059	186	6	class	class	NOUN
bracis-19059	186	7	,	,	PUNCT
bracis-19059	186	8	false	false	ADJ
bracis-19059	186	9	positives	positive	NOUN
bracis-19059	186	10	are	be	AUX
bracis-19059	186	11	mutations	mutation	NOUN
bracis-19059	186	12	predicted	predict	VERB
bracis-19059	186	13	as	as	ADP
bracis-19059	186	14	stabilizing	stabilize	VERB
bracis-19059	186	15	but	but	CCONJ
bracis-19059	186	16	they	they	PRON
bracis-19059	186	17	are	be	AUX
bracis-19059	186	18	destabilizing	destabilizing	ADJ
bracis-19059	186	19	.	.	PUNCT
bracis-19059	187	1	this	this	DET
bracis-19059	187	2	error	error	NOUN
bracis-19059	187	3	can	can	AUX
bracis-19059	187	4	make	make	VERB
bracis-19059	187	5	the	the	DET
bracis-19059	187	6	laboratory	laboratory	NOUN
bracis-19059	187	7	spends	spend	VERB
bracis-19059	187	8	money	money	NOUN
bracis-19059	187	9	and	and	CCONJ
bracis-19059	187	10	time	time	NOUN
bracis-19059	187	11	on	on	ADP
bracis-19059	187	12	a	a	DET
bracis-19059	187	13	not	not	PART
bracis-19059	187	14	viable	viable	ADJ
bracis-19059	187	15	protein	protein	NOUN
bracis-19059	187	16	.	.	PUNCT
bracis-19059	188	1	on	on	ADP
bracis-19059	188	2	the	the	DET
bracis-19059	188	3	other	other	ADJ
bracis-19059	188	4	side	side	NOUN
bracis-19059	188	5	,	,	PUNCT
bracis-19059	188	6	false	false	ADJ
bracis-19059	188	7	negatives	negative	NOUN
bracis-19059	188	8	are	be	AUX
bracis-19059	188	9	mutations	mutation	NOUN
bracis-19059	188	10	predicted	predict	VERB
bracis-19059	188	11	as	as	ADP
bracis-19059	188	12	destabilizing	destabilizing	ADJ
bracis-19059	188	13	but	but	CCONJ
bracis-19059	188	14	they	they	PRON
bracis-19059	188	15	are	be	AUX
bracis-19059	188	16	stabilizing	stabilize	VERB
bracis-19059	188	17	.	.	PUNCT
bracis-19059	189	1	these	these	DET
bracis-19059	189	2	errors	error	NOUN
bracis-19059	189	3	can	can	AUX
bracis-19059	189	4	discard	discard	VERB
bracis-19059	189	5	some	some	DET
bracis-19059	189	6	important	important	ADJ
bracis-19059	189	7	mutation	mutation	NOUN
bracis-19059	189	8	that	that	SCONJ
bracis-19059	189	9	impacts	impact	VERB
bracis-19059	189	10	on	on	ADP
bracis-19059	189	11	the	the	DET
bracis-19059	189	12	protein	protein	NOUN
bracis-19059	189	13	function	function	NOUN
bracis-19059	189	14	of	of	ADP
bracis-19059	189	15	interest	interest	NOUN
bracis-19059	189	16	,	,	PUNCT
bracis-19059	189	17	for	for	ADP
bracis-19059	189	18	example	example	NOUN
bracis-19059	189	19	.	.	PUNCT
bracis-19059	190	1	both	both	DET
bracis-19059	190	2	errors	error	NOUN
bracis-19059	190	3	can	can	AUX
bracis-19059	190	4	impact	impact	VERB
bracis-19059	190	5	experimental	experimental	ADJ
bracis-19059	190	6	laboratory	laboratory	NOUN
bracis-19059	190	7	activities	activity	NOUN
bracis-19059	190	8	according	accord	VERB
bracis-19059	190	9	to	to	ADP
bracis-19059	190	10	the	the	DET
bracis-19059	190	11	project	project	NOUN
bracis-19059	190	12	.	.	PUNCT
bracis-19059	191	1	so	so	ADV
bracis-19059	191	2	,	,	PUNCT
bracis-19059	191	3	we	we	PRON
bracis-19059	191	4	expect	expect	VERB
bracis-19059	191	5	to	to	PART
bracis-19059	191	6	achieve	achieve	VERB
bracis-19059	191	7	good	good	ADJ
bracis-19059	191	8	values	value	NOUN
bracis-19059	191	9	for	for	ADP
bracis-19059	191	10	precision	precision	NOUN
bracis-19059	191	11	and	and	CCONJ
bracis-19059	191	12	recall	recall	NOUN
bracis-19059	191	13	since	since	SCONJ
bracis-19059	191	14	it	it	PRON
bracis-19059	191	15	is	be	AUX
bracis-19059	191	16	important	important	ADJ
bracis-19059	191	17	to	to	PART
bracis-19059	191	18	guarantee	guarantee	VERB
bracis-19059	191	19	that	that	SCONJ
bracis-19059	191	20	the	the	DET
bracis-19059	191	21	stabilizing	stabilizing	NOUN
bracis-19059	191	22	or	or	CCONJ
bracis-19059	191	23	destabilizing	destabilizing	ADJ
bracis-19059	191	24	predictions	prediction	NOUN
bracis-19059	191	25	are	be	AUX
bracis-19059	191	26	correct	correct	ADJ
bracis-19059	191	27	.	.	PUNCT
bracis-19059	192	1	5.2	5.2	NUM
bracis-19059	192	2	experiment	experiment	NOUN
bracis-19059	192	3	2	2	NUM
bracis-19059	192	4	:	:	PUNCT
bracis-19059	192	5	unbalanced	unbalanced	ADJ
bracis-19059	192	6	training	training	NOUN
bracis-19059	192	7	set	set	VERB
bracis-19059	192	8	in	in	ADP
bracis-19059	192	9	experiment	experiment	NOUN
bracis-19059	192	10	2	2	NUM
bracis-19059	192	11	we	we	PRON
bracis-19059	192	12	are	be	AUX
bracis-19059	192	13	training	train	VERB
bracis-19059	192	14	the	the	DET
bracis-19059	192	15	ensemble	ensemble	ADJ
bracis-19059	192	16	models	model	NOUN
bracis-19059	192	17	with	with	ADP
bracis-19059	192	18	unbalanced	unbalanced	ADJ
bracis-19059	192	19	dataset	dataset	NOUN
bracis-19059	192	20	randomly	randomly	ADV
bracis-19059	192	21	dividing	divide	VERB
bracis-19059	192	22	the	the	DET
bracis-19059	192	23	ds3904	ds3904	NOUN
bracis-19059	192	24	into	into	ADP
bracis-19059	192	25	70	70	NUM
bracis-19059	192	26	%	%	NOUN
bracis-19059	192	27	of	of	ADP
bracis-19059	192	28	for	for	ADP
bracis-19059	192	29	training	training	NOUN
bracis-19059	192	30	and	and	CCONJ
bracis-19059	192	31	the	the	DET
bracis-19059	192	32	remaining	remain	VERB
bracis-19059	192	33	30	30	NUM
bracis-19059	192	34	%	%	NOUN
bracis-19059	192	35	of	of	ADP
bracis-19059	192	36	the	the	DET
bracis-19059	192	37	instances	instance	NOUN
bracis-19059	192	38	for	for	ADP
bracis-19059	192	39	testing	testing	NOUN
bracis-19059	192	40	.	.	PUNCT
bracis-19059	193	1	table	table	NOUN
bracis-19059	193	2	 	 	SPACE
bracis-19059	193	3	6	6	NUM
bracis-19059	193	4	presents	present	VERB
bracis-19059	193	5	the	the	DET
bracis-19059	193	6	results	result	NOUN
bracis-19059	193	7	of	of	ADP
bracis-19059	193	8	the	the	DET
bracis-19059	193	9	individual	individual	ADJ
bracis-19059	193	10	tools	tool	NOUN
bracis-19059	193	11	.	.	PUNCT
bracis-19059	194	1	it	it	PRON
bracis-19059	194	2	is	be	AUX
bracis-19059	194	3	observed	observe	VERB
bracis-19059	194	4	that	that	SCONJ
bracis-19059	194	5	although	although	SCONJ
bracis-19059	194	6	they	they	PRON
bracis-19059	194	7	present	present	VERB
bracis-19059	194	8	good	good	ADJ
bracis-19059	194	9	accuracy	accuracy	NOUN
bracis-19059	194	10	,	,	PUNCT
bracis-19059	194	11	the	the	DET
bracis-19059	194	12	values	value	NOUN
bracis-19059	194	13	for	for	ADP
bracis-19059	194	14	precision	precision	NOUN
bracis-19059	194	15	and	and	CCONJ
bracis-19059	194	16	recall	recall	NOUN
bracis-19059	194	17	varies	varie	NOUN
bracis-19059	194	18	.	.	PUNCT
bracis-19059	195	1	some	some	DET
bracis-19059	195	2	tools	tool	NOUN
bracis-19059	195	3	(	(	PUNCT
bracis-19059	195	4	mcsm	mcsm	NOUN
bracis-19059	195	5	and	and	CCONJ
bracis-19059	195	6	popmusic	popmusic	ADJ
bracis-19059	195	7	)	)	PUNCT
bracis-19059	195	8	have	have	VERB
bracis-19059	195	9	better	well	ADJ
bracis-19059	195	10	recall	recall	NOUN
bracis-19059	195	11	values	value	NOUN
bracis-19059	195	12	,	,	PUNCT
bracis-19059	195	13	while	while	SCONJ
bracis-19059	195	14	sdm	sdm	PROPN
bracis-19059	195	15	and	and	CCONJ
bracis-19059	195	16	maestro	maestro	NOUN
bracis-19059	195	17	have	have	VERB
bracis-19059	195	18	better	well	ADJ
bracis-19059	195	19	precision	precision	NOUN
bracis-19059	195	20	(	(	PUNCT
bracis-19059	195	21	around	around	ADP
bracis-19059	195	22	0.6	0.6	NUM
bracis-19059	195	23	)	)	PUNCT
bracis-19059	195	24	.	.	PUNCT
bracis-19059	196	1	table	table	NOUN
bracis-19059	196	2	6	6	NUM
bracis-19059	196	3	.	.	PUNCT
bracis-19059	197	1	evaluation	evaluation	NOUN
bracis-19059	197	2	of	of	ADP
bracis-19059	197	3	individual	individual	ADJ
bracis-19059	197	4	tools	tool	NOUN
bracis-19059	197	5	in	in	ADP
bracis-19059	197	6	experiment	experiment	NOUN
bracis-19059	197	7	2.full	2.full	NUM
bracis-19059	197	8	size	size	NOUN
bracis-19059	197	9	table	table	NOUN
bracis-19059	197	10	tables	table	NOUN
bracis-19059	197	11	 	 	SPACE
bracis-19059	197	12	7	7	NUM
bracis-19059	197	13	and	and	CCONJ
bracis-19059	197	14	8	8	NUM
bracis-19059	197	15	present	present	VERB
bracis-19059	197	16	the	the	DET
bracis-19059	197	17	ensemble	ensemble	ADJ
bracis-19059	197	18	learning	learning	NOUN
bracis-19059	197	19	models	model	NOUN
bracis-19059	197	20	evaluation	evaluation	NOUN
bracis-19059	197	21	for	for	ADP
bracis-19059	197	22	experiment	experiment	NOUN
bracis-19059	197	23	2	2	NUM
bracis-19059	197	24	.	.	PUNCT
bracis-19059	198	1	we	we	PRON
bracis-19059	198	2	can	can	AUX
bracis-19059	198	3	observe	observe	VERB
bracis-19059	198	4	better	well	ADJ
bracis-19059	198	5	accuracy	accuracy	NOUN
bracis-19059	198	6	,	,	PUNCT
bracis-19059	198	7	recall	recall	NOUN
bracis-19059	198	8	and	and	CCONJ
bracis-19059	198	9	precision	precision	NOUN
bracis-19059	198	10	values	value	NOUN
bracis-19059	198	11	.	.	PUNCT
bracis-19059	199	1	boosting	boost	VERB
bracis-19059	199	2	(	(	PUNCT
bracis-19059	199	3	svm	svm	ADJ
bracis-19059	199	4	)	)	PUNCT
bracis-19059	199	5	model	model	NOUN
bracis-19059	199	6	has	have	VERB
bracis-19059	199	7	the	the	DET
bracis-19059	199	8	best	good	ADJ
bracis-19059	199	9	accuracy	accuracy	NOUN
bracis-19059	199	10	(	(	PUNCT
bracis-19059	199	11	0.84	0.84	NUM
bracis-19059	199	12	)	)	PUNCT
bracis-19059	199	13	and	and	CCONJ
bracis-19059	199	14	good	good	ADJ
bracis-19059	199	15	recall	recall	NOUN
bracis-19059	199	16	(	(	PUNCT
bracis-19059	199	17	0.77	0.77	NUM
bracis-19059	199	18	)	)	PUNCT
bracis-19059	199	19	.	.	PUNCT
bracis-19059	200	1	we	we	PRON
bracis-19059	200	2	can	can	AUX
bracis-19059	200	3	see	see	VERB
bracis-19059	200	4	similar	similar	ADJ
bracis-19059	200	5	results	result	NOUN
bracis-19059	200	6	for	for	ADP
bracis-19059	200	7	stacking	stack	VERB
bracis-19059	200	8	learning	learning	NOUN
bracis-19059	200	9	(	(	PUNCT
bracis-19059	200	10	mlp	mlp	NOUN
bracis-19059	200	11	,	,	PUNCT
bracis-19059	200	12	svm	svm	PROPN
bracis-19059	200	13	,	,	PUNCT
bracis-19059	200	14	dt	dt	PUNCT
bracis-19059	200	15	and	and	CCONJ
bracis-19059	200	16	rf	rf	NUM
bracis-19059	200	17	)	)	PUNCT
bracis-19059	200	18	,	,	PUNCT
bracis-19059	200	19	bagging	bagging	NOUN
bracis-19059	200	20	(	(	PUNCT
bracis-19059	200	21	svm	svm	PROPN
bracis-19059	200	22	,	,	PUNCT
bracis-19059	200	23	dt	dt	PUNCT
bracis-19059	200	24	and	and	CCONJ
bracis-19059	200	25	mlp	mlp	PROPN
bracis-19059	200	26	)	)	PUNCT
bracis-19059	200	27	and	and	CCONJ
bracis-19059	200	28	also	also	ADV
bracis-19059	200	29	boosting	boost	VERB
bracis-19059	200	30	(	(	PUNCT
bracis-19059	200	31	mlp	mlp	NOUN
bracis-19059	200	32	)	)	PUNCT
bracis-19059	200	33	.	.	PUNCT
bracis-19059	201	1	table	table	NOUN
bracis-19059	201	2	7	7	NUM
bracis-19059	201	3	.	.	PUNCT
bracis-19059	201	4	evaluation	evaluation	NOUN
bracis-19059	201	5	of	of	ADP
bracis-19059	201	6	stacking	stack	VERB
bracis-19059	201	7	ensemble	ensemble	ADJ
bracis-19059	201	8	in	in	ADP
bracis-19059	201	9	experiment	experiment	NOUN
bracis-19059	201	10	2.full	2.full	NUM
bracis-19059	201	11	size	size	NOUN
bracis-19059	201	12	table	table	NOUN
bracis-19059	201	13	table	table	NOUN
bracis-19059	201	14	8	8	NUM
bracis-19059	201	15	.	.	PUNCT
bracis-19059	201	16	evaluation	evaluation	NOUN
bracis-19059	201	17	of	of	ADP
bracis-19059	201	18	bagging	bagging	NOUN
bracis-19059	201	19	/	/	SYM
bracis-19059	201	20	boosting	boost	VERB
bracis-19059	201	21	in	in	ADP
bracis-19059	201	22	experiment	experiment	NOUN
bracis-19059	201	23	2.full	2.full	NUM
bracis-19059	201	24	size	size	NOUN
bracis-19059	201	25	table	table	NOUN
bracis-19059	201	26	these	these	PRON
bracis-19059	201	27	are	be	AUX
bracis-19059	201	28	good	good	ADJ
bracis-19059	201	29	models	model	NOUN
bracis-19059	201	30	for	for	ADP
bracis-19059	201	31	avoiding	avoid	VERB
bracis-19059	201	32	to	to	PART
bracis-19059	201	33	incorrectly	incorrectly	ADV
bracis-19059	201	34	predict	predict	VERB
bracis-19059	201	35	as	as	ADP
bracis-19059	201	36	destabilizing	destabilize	VERB
bracis-19059	201	37	a	a	DET
bracis-19059	201	38	stabilizing	stabilize	VERB
bracis-19059	201	39	mutation	mutation	NOUN
bracis-19059	201	40	(	(	PUNCT
bracis-19059	201	41	falses	false	NOUN
bracis-19059	201	42	negatives	negative	NOUN
bracis-19059	201	43	)	)	PUNCT
bracis-19059	201	44	.	.	PUNCT
bracis-19059	202	1	on	on	ADP
bracis-19059	202	2	the	the	DET
bracis-19059	202	3	other	other	ADJ
bracis-19059	202	4	side	side	NOUN
bracis-19059	202	5	,	,	PUNCT
bracis-19059	202	6	stacking	stack	VERB
bracis-19059	202	7	learning	learning	NOUN
bracis-19059	202	8	,	,	PUNCT
bracis-19059	202	9	bagging	bag	VERB
bracis-19059	202	10	and	and	CCONJ
bracis-19059	202	11	boosting	boost	VERB
bracis-19059	202	12	with	with	ADP
bracis-19059	202	13	naive	naive	ADJ
bracis-19059	202	14	bayes	bayes	NOUN
bracis-19059	202	15	(	(	PUNCT
bracis-19059	202	16	nb	nb	NOUN
bracis-19059	202	17	)	)	PUNCT
bracis-19059	202	18	also	also	ADV
bracis-19059	202	19	have	have	VERB
bracis-19059	202	20	good	good	ADJ
bracis-19059	202	21	accuracy	accuracy	NOUN
bracis-19059	202	22	but	but	CCONJ
bracis-19059	202	23	presented	present	VERB
bracis-19059	202	24	better	well	ADJ
bracis-19059	202	25	precision	precision	NOUN
bracis-19059	202	26	values	value	NOUN
bracis-19059	202	27	.	.	PUNCT
bracis-19059	203	1	it	it	PRON
bracis-19059	203	2	means	mean	VERB
bracis-19059	203	3	that	that	SCONJ
bracis-19059	203	4	ensemble	ensemble	ADJ
bracis-19059	203	5	models	model	NOUN
bracis-19059	203	6	with	with	ADP
bracis-19059	203	7	nb	nb	PROPN
bracis-19059	203	8	can	can	AUX
bracis-19059	203	9	be	be	AUX
bracis-19059	203	10	good	good	ADJ
bracis-19059	203	11	options	option	NOUN
bracis-19059	203	12	for	for	ADP
bracis-19059	203	13	avoiding	avoid	VERB
bracis-19059	203	14	to	to	PART
bracis-19059	203	15	predict	predict	VERB
bracis-19059	203	16	destabilizing	destabilizing	ADJ
bracis-19059	203	17	mutations	mutation	NOUN
bracis-19059	203	18	as	as	ADP
bracis-19059	203	19	stabilizing	stabilize	VERB
bracis-19059	203	20	(	(	PUNCT
bracis-19059	203	21	falses	false	NOUN
bracis-19059	203	22	positives	positive	NOUN
bracis-19059	203	23	)	)	PUNCT
bracis-19059	203	24	.	.	PUNCT
bracis-19059	204	1	6	6	NUM
bracis-19059	204	2	conclusion	conclusion	NOUN
bracis-19059	204	3	the	the	DET
bracis-19059	204	4	knowledge	knowledge	NOUN
bracis-19059	204	5	about	about	ADP
bracis-19059	204	6	the	the	DET
bracis-19059	204	7	impact	impact	NOUN
bracis-19059	204	8	on	on	ADP
bracis-19059	204	9	proteins	protein	NOUN
bracis-19059	204	10	stability	stability	NOUN
bracis-19059	204	11	upon	upon	SCONJ
bracis-19059	204	12	point	point	NOUN
bracis-19059	204	13	mutations	mutation	NOUN
bracis-19059	204	14	is	be	AUX
bracis-19059	204	15	an	an	DET
bracis-19059	204	16	important	important	ADJ
bracis-19059	204	17	scientific	scientific	ADJ
bracis-19059	204	18	and	and	CCONJ
bracis-19059	204	19	commercial	commercial	ADJ
bracis-19059	204	20	research	research	NOUN
bracis-19059	204	21	topic	topic	NOUN
bracis-19059	204	22	.	.	PUNCT
bracis-19059	205	1	one	one	NUM
bracis-19059	205	2	way	way	NOUN
bracis-19059	205	3	is	be	AUX
bracis-19059	205	4	to	to	PART
bracis-19059	205	5	computationally	computationally	ADV
bracis-19059	205	6	predict	predict	VERB
bracis-19059	205	7	the	the	DET
bracis-19059	205	8	variation	variation	NOUN
bracis-19059	205	9	of	of	ADP
bracis-19059	205	10	the	the	DET
bracis-19059	205	11	free	free	ADJ
bracis-19059	205	12	energy	energy	NOUN
bracis-19059	205	13	\(\vardelta	\(\vardelta	NOUN
bracis-19059	205	14	\vardelta	\vardelta	X
bracis-19059	205	15	g\	g\	NOUN
bracis-19059	205	16	)	)	PUNCT
bracis-19059	205	17	and	and	CCONJ
bracis-19059	205	18	its	its	PRON
bracis-19059	205	19	consequently	consequently	ADV
bracis-19059	205	20	impact	impact	NOUN
bracis-19059	205	21	on	on	ADP
bracis-19059	205	22	protein	protein	NOUN
bracis-19059	205	23	stability	stability	NOUN
bracis-19059	205	24	.	.	PUNCT
bracis-19059	206	1	there	there	PRON
bracis-19059	206	2	are	be	VERB
bracis-19059	206	3	different	different	ADJ
bracis-19059	206	4	methods	method	NOUN
bracis-19059	206	5	and	and	CCONJ
bracis-19059	206	6	tools	tool	NOUN
bracis-19059	206	7	for	for	ADP
bracis-19059	206	8	this	this	DET
bracis-19059	206	9	purpose	purpose	NOUN
bracis-19059	206	10	that	that	PRON
bracis-19059	206	11	do	do	AUX
bracis-19059	206	12	not	not	PART
bracis-19059	206	13	always	always	ADV
bracis-19059	206	14	obtain	obtain	VERB
bracis-19059	206	15	similar	similar	ADJ
bracis-19059	206	16	results	result	NOUN
bracis-19059	206	17	for	for	ADP
bracis-19059	206	18	the	the	DET
bracis-19059	206	19	same	same	ADJ
bracis-19059	206	20	entries	entry	NOUN
bracis-19059	206	21	.	.	PUNCT
bracis-19059	207	1	besides	besides	SCONJ
bracis-19059	207	2	,	,	PUNCT
bracis-19059	207	3	these	these	DET
bracis-19059	207	4	predictions	prediction	NOUN
bracis-19059	207	5	are	be	AUX
bracis-19059	207	6	used	use	VERB
bracis-19059	207	7	to	to	PART
bracis-19059	207	8	define	define	VERB
bracis-19059	207	9	point	point	NOUN
bracis-19059	207	10	mutations	mutation	NOUN
bracis-19059	207	11	on	on	ADP
bracis-19059	207	12	protein	protein	NOUN
bracis-19059	207	13	structures	structure	NOUN
bracis-19059	207	14	that	that	PRON
bracis-19059	207	15	are	be	AUX
bracis-19059	207	16	experimentally	experimentally	ADV
bracis-19059	207	17	generated	generate	VERB
bracis-19059	207	18	,	,	PUNCT
bracis-19059	207	19	which	which	PRON
bracis-19059	207	20	is	be	AUX
bracis-19059	207	21	expensive	expensive	ADJ
bracis-19059	207	22	in	in	ADP
bracis-19059	207	23	terms	term	NOUN
bracis-19059	207	24	of	of	ADP
bracis-19059	207	25	time	time	NOUN
bracis-19059	207	26	and	and	CCONJ
bracis-19059	207	27	costs	cost	NOUN
bracis-19059	207	28	.	.	PUNCT
bracis-19059	208	1	errors	error	NOUN
bracis-19059	208	2	on	on	ADP
bracis-19059	208	3	this	this	DET
bracis-19059	208	4	predictions	prediction	NOUN
bracis-19059	208	5	can	can	AUX
bracis-19059	208	6	have	have	VERB
bracis-19059	208	7	important	important	ADJ
bracis-19059	208	8	impacts	impact	NOUN
bracis-19059	208	9	.	.	PUNCT
bracis-19059	209	1	for	for	ADP
bracis-19059	209	2	example	example	NOUN
bracis-19059	209	3	,	,	PUNCT
bracis-19059	209	4	consider	consider	VERB
bracis-19059	209	5	a	a	DET
bracis-19059	209	6	point	point	NOUN
bracis-19059	209	7	mutation	mutation	NOUN
bracis-19059	209	8	as	as	ADP
bracis-19059	209	9	destabilizing	destabilizing	ADJ
bracis-19059	209	10	but	but	CCONJ
bracis-19059	209	11	when	when	SCONJ
bracis-19059	209	12	it	it	PRON
bracis-19059	209	13	is	be	AUX
bracis-19059	209	14	stabilizing	stabilize	VERB
bracis-19059	209	15	can	can	AUX
bracis-19059	209	16	discard	discard	VERB
bracis-19059	209	17	this	this	DET
bracis-19059	209	18	candidate	candidate	NOUN
bracis-19059	209	19	.	.	PUNCT
bracis-19059	210	1	at	at	ADP
bracis-19059	210	2	the	the	DET
bracis-19059	210	3	same	same	ADJ
bracis-19059	210	4	time	time	NOUN
bracis-19059	210	5	that	that	PRON
bracis-19059	210	6	a	a	DET
bracis-19059	210	7	wrong	wrong	ADJ
bracis-19059	210	8	prediction	prediction	NOUN
bracis-19059	210	9	of	of	ADP
bracis-19059	210	10	stabilizing	stabilizing	NOUN
bracis-19059	210	11	when	when	SCONJ
bracis-19059	210	12	the	the	DET
bracis-19059	210	13	mutation	mutation	NOUN
bracis-19059	210	14	destabilizes	destabilize	VERB
bracis-19059	210	15	the	the	DET
bracis-19059	210	16	protein	protein	NOUN
bracis-19059	210	17	structure	structure	NOUN
bracis-19059	210	18	can	can	AUX
bracis-19059	210	19	made	make	VERB
bracis-19059	210	20	the	the	DET
bracis-19059	210	21	laboratory	laboratory	NOUN
bracis-19059	210	22	spends	spend	VERB
bracis-19059	210	23	money	money	NOUN
bracis-19059	210	24	and	and	CCONJ
bracis-19059	210	25	time	time	NOUN
bracis-19059	210	26	on	on	ADP
bracis-19059	210	27	a	a	DET
bracis-19059	210	28	not	not	PART
bracis-19059	210	29	viable	viable	ADJ
bracis-19059	210	30	protein	protein	NOUN
bracis-19059	210	31	.	.	PUNCT
bracis-19059	211	1	thus	thus	ADV
bracis-19059	211	2	,	,	PUNCT
bracis-19059	211	3	in	in	ADP
bracis-19059	211	4	this	this	DET
bracis-19059	211	5	paper	paper	NOUN
bracis-19059	211	6	we	we	PRON
bracis-19059	211	7	propose	propose	VERB
bracis-19059	211	8	to	to	PART
bracis-19059	211	9	aggregate	aggregate	VERB
bracis-19059	211	10	the	the	DET
bracis-19059	211	11	results	result	NOUN
bracis-19059	211	12	from	from	ADP
bracis-19059	211	13	different	different	ADJ
bracis-19059	211	14	stability	stability	NOUN
bracis-19059	211	15	prediction	prediction	NOUN
bracis-19059	211	16	tools	tool	NOUN
bracis-19059	211	17	using	use	VERB
bracis-19059	211	18	stacking	stacking	NOUN
bracis-19059	211	19	,	,	PUNCT
bracis-19059	211	20	bagging	bagging	NOUN
bracis-19059	211	21	/	/	SYM
bracis-19059	211	22	boosting	boost	VERB
bracis-19059	211	23	ensemble	ensemble	ADJ
bracis-19059	211	24	learning	learning	NOUN
bracis-19059	211	25	techniques	technique	NOUN
bracis-19059	211	26	achieving	achieve	VERB
bracis-19059	211	27	to	to	PART
bracis-19059	211	28	obtain	obtain	VERB
bracis-19059	211	29	models	model	NOUN
bracis-19059	211	30	with	with	ADP
bracis-19059	211	31	not	not	PART
bracis-19059	211	32	only	only	ADV
bracis-19059	211	33	good	good	ADJ
bracis-19059	211	34	accuracy	accuracy	NOUN
bracis-19059	211	35	but	but	CCONJ
bracis-19059	211	36	also	also	ADV
bracis-19059	211	37	good	good	ADJ
bracis-19059	211	38	precision	precision	NOUN
bracis-19059	211	39	and/or	and/or	CCONJ
bracis-19059	211	40	recall	recall	NOUN
bracis-19059	211	41	.	.	PUNCT
bracis-19059	212	1	in	in	ADP
bracis-19059	212	2	our	our	PRON
bracis-19059	212	3	proposed	propose	VERB
bracis-19059	212	4	methodology	methodology	NOUN
bracis-19059	212	5	we	we	PRON
bracis-19059	212	6	are	be	AUX
bracis-19059	212	7	considering	consider	VERB
bracis-19059	212	8	six	six	NUM
bracis-19059	212	9	individual	individual	ADJ
bracis-19059	212	10	\(\vardelta	\(\vardelta	NOUN
bracis-19059	212	11	\vardelta	\vardelta	PROPN
bracis-19059	212	12	g\	g\	NOUN
bracis-19059	212	13	)	)	PUNCT
bracis-19059	212	14	predictors	predictor	NOUN
bracis-19059	212	15	:	:	PUNCT
bracis-19059	212	16	cupsat	cupsat	VERB
bracis-19059	212	17	[	[	PUNCT
bracis-19059	212	18	17	17	NUM
bracis-19059	212	19	]	]	PUNCT
bracis-19059	212	20	,	,	PUNCT
bracis-19059	212	21	sdm	sdm	PROPN
bracis-19059	213	1	[	[	X
bracis-19059	213	2	25	25	NUM
bracis-19059	213	3	]	]	PUNCT
bracis-19059	213	4	,	,	PUNCT
bracis-19059	213	5	mcsm	mcsm	NOUN
bracis-19059	213	6	[	[	X
bracis-19059	213	7	18	18	NUM
bracis-19059	213	8	]	]	PUNCT
bracis-19059	213	9	,	,	PUNCT
bracis-19059	213	10	duet	duet	NOUN
bracis-19059	213	11	[	[	X
bracis-19059	213	12	19	19	NUM
bracis-19059	213	13	]	]	PUNCT
bracis-19059	213	14	,	,	PUNCT
bracis-19059	213	15	maestro	maestro	NOUN
bracis-19059	213	16	[	[	X
bracis-19059	213	17	14	14	NUM
bracis-19059	213	18	]	]	PUNCT
bracis-19059	213	19	and	and	CCONJ
bracis-19059	213	20	popmusic	popmusic	ADJ
bracis-19059	214	1	[	[	X
bracis-19059	214	2	7	7	NUM
bracis-19059	214	3	]	]	PUNCT
bracis-19059	214	4	.	.	PUNCT
bracis-19059	215	1	we	we	PRON
bracis-19059	215	2	prepared	prepare	VERB
bracis-19059	215	3	an	an	DET
bracis-19059	215	4	input	input	NOUN
bracis-19059	215	5	dataset	dataset	VERB
bracis-19059	215	6	from	from	ADP
bracis-19059	215	7	protherm	protherm	NOUN
bracis-19059	215	8	[	[	X
bracis-19059	215	9	2	2	NUM
bracis-19059	215	10	]	]	PUNCT
bracis-19059	215	11	with	with	ADP
bracis-19059	215	12	3,904	3,904	NUM
bracis-19059	215	13	instances	instance	NOUN
bracis-19059	215	14	about	about	ADP
bracis-19059	215	15	wild	wild	ADJ
bracis-19059	215	16	-	-	PUNCT
bracis-19059	215	17	type	type	NOUN
bracis-19059	215	18	and	and	CCONJ
bracis-19059	215	19	mutation	mutation	NOUN
bracis-19059	215	20	proteins	protein	NOUN
bracis-19059	215	21	.	.	PUNCT
bracis-19059	216	1	after	after	ADP
bracis-19059	216	2	submitting	submit	VERB
bracis-19059	216	3	this	this	DET
bracis-19059	216	4	list	list	NOUN
bracis-19059	216	5	to	to	ADP
bracis-19059	216	6	the	the	DET
bracis-19059	216	7	tools	tool	NOUN
bracis-19059	216	8	we	we	PRON
bracis-19059	216	9	obtained	obtain	VERB
bracis-19059	216	10	our	our	PRON
bracis-19059	216	11	meta	meta	ADJ
bracis-19059	216	12	-	-	PUNCT
bracis-19059	216	13	data	datum	NOUN
bracis-19059	216	14	composed	compose	VERB
bracis-19059	216	15	by	by	ADP
bracis-19059	216	16	their	their	PRON
bracis-19059	216	17	\(\vardelta	\(\vardelta	NOUN
bracis-19059	216	18	\vardelta	\vardelta	ADP
bracis-19059	216	19	g\	g\	NOUN
bracis-19059	216	20	)	)	PUNCT
bracis-19059	216	21	predictions	prediction	NOUN
bracis-19059	216	22	.	.	PUNCT
bracis-19059	217	1	having	have	VERB
bracis-19059	217	2	this	this	DET
bracis-19059	217	3	meta	meta	ADJ
bracis-19059	217	4	-	-	PUNCT
bracis-19059	217	5	data	data	NOUN
bracis-19059	217	6	,	,	PUNCT
bracis-19059	217	7	we	we	PRON
bracis-19059	217	8	applied	apply	VERB
bracis-19059	217	9	stacking	stack	VERB
bracis-19059	217	10	ensemble	ensemble	ADJ
bracis-19059	217	11	with	with	ADP
bracis-19059	217	12	meta	meta	NOUN
bracis-19059	217	13	-	-	PUNCT
bracis-19059	217	14	classifiers	classifier	NOUN
bracis-19059	217	15	(	(	PUNCT
bracis-19059	217	16	rf	rf	NOUN
bracis-19059	217	17	,	,	PUNCT
bracis-19059	217	18	dt	dt	NOUN
bracis-19059	217	19	,	,	PUNCT
bracis-19059	217	20	svm	svm	PROPN
bracis-19059	217	21	,	,	PUNCT
bracis-19059	217	22	mlp	mlp	PROPN
bracis-19059	217	23	and	and	CCONJ
bracis-19059	217	24	nb	nb	PROPN
bracis-19059	217	25	)	)	PUNCT
bracis-19059	217	26	,	,	PUNCT
bracis-19059	217	27	bagging	bagging	NOUN
bracis-19059	217	28	(	(	PUNCT
bracis-19059	217	29	svm	svm	PROPN
bracis-19059	217	30	,	,	PUNCT
bracis-19059	217	31	dt	dt	PROPN
bracis-19059	217	32	,	,	PUNCT
bracis-19059	217	33	mlp	mlp	PROPN
bracis-19059	217	34	and	and	CCONJ
bracis-19059	217	35	nv	nv	PROPN
bracis-19059	217	36	)	)	PUNCT
bracis-19059	217	37	and	and	CCONJ
bracis-19059	217	38	boosting	boost	VERB
bracis-19059	217	39	.	.	PUNCT
bracis-19059	218	1	for	for	ADP
bracis-19059	218	2	both	both	CCONJ
bracis-19059	218	3	ensemble	ensemble	ADJ
bracis-19059	218	4	techniques	technique	NOUN
bracis-19059	218	5	we	we	PRON
bracis-19059	218	6	validated	validate	VERB
bracis-19059	218	7	considering	consider	VERB
bracis-19059	218	8	two	two	NUM
bracis-19059	218	9	different	different	ADJ
bracis-19059	218	10	experiments	experiment	NOUN
bracis-19059	218	11	according	accord	VERB
bracis-19059	218	12	to	to	ADP
bracis-19059	218	13	the	the	DET
bracis-19059	218	14	training	training	NOUN
bracis-19059	218	15	set	set	NOUN
bracis-19059	218	16	.	.	PUNCT
bracis-19059	219	1	in	in	ADP
bracis-19059	219	2	experiment	experiment	NOUN
bracis-19059	219	3	1	1	NUM
bracis-19059	219	4	(	(	PUNCT
bracis-19059	219	5	balanced	balanced	ADJ
bracis-19059	219	6	training	training	NOUN
bracis-19059	219	7	set	set	NOUN
bracis-19059	219	8	)	)	PUNCT
bracis-19059	219	9	results	result	NOUN
bracis-19059	219	10	we	we	PRON
bracis-19059	219	11	can	can	AUX
bracis-19059	219	12	observe	observe	VERB
bracis-19059	219	13	that	that	SCONJ
bracis-19059	219	14	even	even	ADV
bracis-19059	219	15	all	all	DET
bracis-19059	219	16	individual	individual	ADJ
bracis-19059	219	17	tools	tool	NOUN
bracis-19059	219	18	obtained	obtain	VERB
bracis-19059	219	19	good	good	ADJ
bracis-19059	219	20	accuracy	accuracy	NOUN
bracis-19059	219	21	values	value	NOUN
bracis-19059	219	22	,	,	PUNCT
bracis-19059	219	23	they	they	PRON
bracis-19059	219	24	presented	present	VERB
bracis-19059	219	25	low	low	ADJ
bracis-19059	219	26	precision	precision	NOUN
bracis-19059	219	27	.	.	PUNCT
bracis-19059	220	1	on	on	ADP
bracis-19059	220	2	the	the	DET
bracis-19059	220	3	other	other	ADJ
bracis-19059	220	4	side	side	NOUN
bracis-19059	220	5	,	,	PUNCT
bracis-19059	220	6	both	both	PRON
bracis-19059	220	7	stacking	stack	VERB
bracis-19059	220	8	and	and	CCONJ
bracis-19059	220	9	bagging	bagging	NOUN
bracis-19059	220	10	/	/	SYM
bracis-19059	220	11	boosting	boost	VERB
bracis-19059	220	12	ensemble	ensemble	ADJ
bracis-19059	220	13	models	model	NOUN
bracis-19059	220	14	obtained	obtain	VERB
bracis-19059	220	15	also	also	ADV
bracis-19059	220	16	good	good	ADJ
bracis-19059	220	17	accuracy	accuracy	NOUN
bracis-19059	220	18	but	but	CCONJ
bracis-19059	220	19	with	with	ADP
bracis-19059	220	20	better	well	ADJ
bracis-19059	220	21	precision	precision	NOUN
bracis-19059	220	22	.	.	PUNCT
bracis-19059	221	1	in	in	ADP
bracis-19059	221	2	experiment	experiment	NOUN
bracis-19059	221	3	2	2	NUM
bracis-19059	221	4	(	(	PUNCT
bracis-19059	221	5	unbalanced	unbalanced	ADJ
bracis-19059	221	6	training	training	NOUN
bracis-19059	221	7	set	set	NOUN
bracis-19059	221	8	)	)	PUNCT
bracis-19059	221	9	results	result	NOUN
bracis-19059	221	10	we	we	PRON
bracis-19059	221	11	can	can	AUX
bracis-19059	221	12	observe	observe	VERB
bracis-19059	221	13	better	well	ADJ
bracis-19059	221	14	accuracy	accuracy	NOUN
bracis-19059	221	15	,	,	PUNCT
bracis-19059	221	16	recall	recall	NOUN
bracis-19059	221	17	and	and	CCONJ
bracis-19059	221	18	precision	precision	NOUN
bracis-19059	221	19	values	value	NOUN
bracis-19059	221	20	for	for	ADP
bracis-19059	221	21	ensemble	ensemble	ADJ
bracis-19059	221	22	models	model	NOUN
bracis-19059	221	23	.	.	PUNCT
bracis-19059	222	1	boosting(svm	boosting(svm	NOUN
bracis-19059	222	2	)	)	PUNCT
bracis-19059	222	3	obtained	obtain	VERB
bracis-19059	222	4	the	the	DET
bracis-19059	222	5	best	good	ADJ
bracis-19059	222	6	accuracy	accuracy	NOUN
bracis-19059	222	7	(	(	PUNCT
bracis-19059	222	8	0.84	0.84	NUM
bracis-19059	222	9	)	)	PUNCT
bracis-19059	222	10	and	and	CCONJ
bracis-19059	222	11	good	good	ADJ
bracis-19059	222	12	recall	recall	NOUN
bracis-19059	222	13	(	(	PUNCT
bracis-19059	222	14	0.77	0.77	NUM
bracis-19059	222	15	)	)	PUNCT
bracis-19059	222	16	.	.	PUNCT
bracis-19059	223	1	we	we	PRON
bracis-19059	223	2	can	can	AUX
bracis-19059	223	3	see	see	VERB
bracis-19059	223	4	similar	similar	ADJ
bracis-19059	223	5	results	result	NOUN
bracis-19059	223	6	for	for	ADP
bracis-19059	223	7	stacking	stack	VERB
bracis-19059	223	8	learning	learning	NOUN
bracis-19059	223	9	(	(	PUNCT
bracis-19059	223	10	mlp	mlp	NOUN
bracis-19059	223	11	,	,	PUNCT
bracis-19059	223	12	svm	svm	PROPN
bracis-19059	223	13	,	,	PUNCT
bracis-19059	223	14	dt	dt	PUNCT
bracis-19059	223	15	and	and	CCONJ
bracis-19059	223	16	rf	rf	NUM
bracis-19059	223	17	)	)	PUNCT
bracis-19059	223	18	,	,	PUNCT
bracis-19059	223	19	bagging	bagging	NOUN
bracis-19059	223	20	(	(	PUNCT
bracis-19059	223	21	svm	svm	PROPN
bracis-19059	223	22	,	,	PUNCT
bracis-19059	223	23	dt	dt	PUNCT
bracis-19059	223	24	and	and	CCONJ
bracis-19059	223	25	mlp	mlp	PROPN
bracis-19059	223	26	)	)	PUNCT
bracis-19059	223	27	and	and	CCONJ
bracis-19059	223	28	also	also	ADV
bracis-19059	223	29	boosting	boost	VERB
bracis-19059	223	30	(	(	PUNCT
bracis-19059	223	31	mlp	mlp	NOUN
bracis-19059	223	32	)	)	PUNCT
bracis-19059	223	33	.	.	PUNCT
bracis-19059	224	1	these	these	PRON
bracis-19059	224	2	are	be	AUX
bracis-19059	224	3	good	good	ADJ
bracis-19059	224	4	models	model	NOUN
bracis-19059	224	5	for	for	ADP
bracis-19059	224	6	avoiding	avoid	VERB
bracis-19059	224	7	to	to	PART
bracis-19059	224	8	incorrectly	incorrectly	ADV
bracis-19059	224	9	predict	predict	VERB
bracis-19059	224	10	as	as	ADP
bracis-19059	224	11	destabilizing	destabilize	VERB
bracis-19059	224	12	a	a	DET
bracis-19059	224	13	stabilizing	stabilize	VERB
bracis-19059	224	14	mutation	mutation	NOUN
bracis-19059	224	15	.	.	PUNCT
bracis-19059	225	1	on	on	ADP
bracis-19059	225	2	the	the	DET
bracis-19059	225	3	other	other	ADJ
bracis-19059	225	4	side	side	NOUN
bracis-19059	225	5	,	,	PUNCT
bracis-19059	225	6	stacking	stack	VERB
bracis-19059	225	7	learning	learning	NOUN
bracis-19059	225	8	,	,	PUNCT
bracis-19059	225	9	bagging	bag	VERB
bracis-19059	225	10	and	and	CCONJ
bracis-19059	225	11	boosting	boost	VERB
bracis-19059	225	12	with	with	ADP
bracis-19059	225	13	naive	naive	ADJ
bracis-19059	225	14	bayes	bayes	NOUN
bracis-19059	225	15	(	(	PUNCT
bracis-19059	225	16	nb	nb	NOUN
bracis-19059	225	17	)	)	PUNCT
bracis-19059	225	18	also	also	ADV
bracis-19059	225	19	have	have	VERB
bracis-19059	225	20	good	good	ADJ
bracis-19059	225	21	accuracy	accuracy	NOUN
bracis-19059	225	22	but	but	CCONJ
bracis-19059	225	23	presented	present	VERB
bracis-19059	225	24	better	well	ADJ
bracis-19059	225	25	precision	precision	NOUN
bracis-19059	225	26	values	value	NOUN
bracis-19059	225	27	.	.	PUNCT
bracis-19059	226	1	it	it	PRON
bracis-19059	226	2	means	mean	VERB
bracis-19059	226	3	that	that	SCONJ
bracis-19059	226	4	ensemble	ensemble	ADJ
bracis-19059	226	5	models	model	NOUN
bracis-19059	226	6	with	with	ADP
bracis-19059	226	7	nb	nb	PROPN
bracis-19059	226	8	can	can	AUX
bracis-19059	226	9	be	be	AUX
bracis-19059	226	10	good	good	ADJ
bracis-19059	226	11	options	option	NOUN
bracis-19059	226	12	for	for	ADP
bracis-19059	226	13	avoiding	avoid	VERB
bracis-19059	226	14	to	to	PART
bracis-19059	226	15	predict	predict	VERB
bracis-19059	226	16	destabilizing	destabilizing	ADJ
bracis-19059	226	17	mutations	mutation	NOUN
bracis-19059	226	18	as	as	ADP
bracis-19059	226	19	stabilizing	stabilize	VERB
bracis-19059	226	20	.	.	PUNCT
bracis-19059	227	1	thus	thus	ADV
bracis-19059	227	2	,	,	PUNCT
bracis-19059	227	3	according	accord	VERB
bracis-19059	227	4	with	with	ADP
bracis-19059	227	5	the	the	DET
bracis-19059	227	6	results	result	NOUN
bracis-19059	227	7	,	,	PUNCT
bracis-19059	227	8	our	our	PRON
bracis-19059	227	9	proposed	propose	VERB
bracis-19059	227	10	ensemble	ensemble	ADJ
bracis-19059	227	11	approach	approach	NOUN
bracis-19059	227	12	is	be	AUX
bracis-19059	227	13	appropriate	appropriate	ADJ
bracis-19059	227	14	to	to	PART
bracis-19059	227	15	predict	predict	VERB
bracis-19059	227	16	the	the	DET
bracis-19059	227	17	effect	effect	NOUN
bracis-19059	227	18	of	of	ADP
bracis-19059	227	19	point	point	NOUN
bracis-19059	227	20	mutations	mutation	NOUN
bracis-19059	227	21	on	on	ADP
bracis-19059	227	22	protein	protein	NOUN
bracis-19059	227	23	stability	stability	NOUN
bracis-19059	227	24	showing	show	VERB
bracis-19059	227	25	more	more	ADV
bracis-19059	227	26	reliable	reliable	ADJ
bracis-19059	227	27	results	result	NOUN
bracis-19059	227	28	than	than	ADP
bracis-19059	227	29	the	the	DET
bracis-19059	227	30	individual	individual	ADJ
bracis-19059	227	31	tools	tool	NOUN
bracis-19059	227	32	.	.	PUNCT
bracis-19059	228	1	as	as	ADP
bracis-19059	228	2	future	future	ADJ
bracis-19059	228	3	work	work	NOUN
bracis-19059	228	4	,	,	PUNCT
bracis-19059	228	5	we	we	PRON
bracis-19059	228	6	can	can	AUX
bracis-19059	228	7	combine	combine	VERB
bracis-19059	228	8	the	the	DET
bracis-19059	228	9	individual	individual	ADJ
bracis-19059	228	10	tools	tool	NOUN
bracis-19059	228	11	using	use	VERB
bracis-19059	228	12	genetic	genetic	ADJ
bracis-19059	228	13	algorithms	algorithm	NOUN
bracis-19059	228	14	to	to	PART
bracis-19059	228	15	determine	determine	VERB
bracis-19059	228	16	the	the	DET
bracis-19059	228	17	weight	weight	NOUN
bracis-19059	228	18	of	of	ADP
bracis-19059	228	19	each	each	DET
bracis-19059	228	20	\(\vardelta	\(\vardelta	NOUN
bracis-19059	229	1	\vardelta	\vardelta	NOUN
bracis-19059	229	2	\)g	\)g	PUNCT
bracis-19059	229	3	predicted	predict	VERB
bracis-19059	229	4	and	and	CCONJ
bracis-19059	229	5	also	also	ADV
bracis-19059	229	6	include	include	VERB
bracis-19059	229	7	more	more	ADJ
bracis-19059	229	8	tools	tool	NOUN
bracis-19059	229	9	in	in	ADP
bracis-19059	229	10	the	the	DET
bracis-19059	229	11	ensemble	ensemble	NOUN
bracis-19059	229	12	.	.	PUNCT
bracis-19059	230	1	in	in	ADP
bracis-19059	230	2	addition	addition	NOUN
bracis-19059	230	3	,	,	PUNCT
bracis-19059	230	4	other	other	ADJ
bracis-19059	230	5	balancing	balancing	NOUN
bracis-19059	230	6	strategies	strategy	NOUN
bracis-19059	230	7	can	can	AUX
bracis-19059	230	8	be	be	AUX
bracis-19059	230	9	performed	perform	VERB
bracis-19059	230	10	on	on	ADP
bracis-19059	230	11	the	the	DET
bracis-19059	230	12	training	training	NOUN
bracis-19059	230	13	datasets	dataset	NOUN
bracis-19059	230	14	.	.	PUNCT
bracis-19059	231	1	references	reference	NOUN
bracis-19059	231	2	auclair	auclair	PROPN
bracis-19059	231	3	,	,	PUNCT
bracis-19059	231	4	j.	j.	PROPN
bracis-19059	231	5	,	,	PUNCT
bracis-19059	231	6	et	et	PROPN
bracis-19059	231	7	al	al	PROPN
bracis-19059	231	8	.	.	PROPN
bracis-19059	231	9	:	:	PUNCT
bracis-19059	232	1	systematic	systematic	ADJ
bracis-19059	232	2	mrna	mrna	PROPN
bracis-19059	232	3	analysis	analysis	NOUN
bracis-19059	232	4	for	for	ADP
bracis-19059	232	5	the	the	DET
bracis-19059	232	6	effect	effect	NOUN
bracis-19059	232	7	of	of	ADP
bracis-19059	232	8	mlh1	mlh1	PROPN
bracis-19059	232	9	and	and	CCONJ
bracis-19059	232	10	msh2	msh2	NOUN
bracis-19059	232	11	missense	missense	NOUN
bracis-19059	232	12	and	and	CCONJ
bracis-19059	232	13	silent	silent	ADJ
bracis-19059	232	14	mutations	mutation	NOUN
bracis-19059	232	15	on	on	ADP
bracis-19059	232	16	aberrant	aberrant	ADJ
bracis-19059	232	17	splicing	splicing	NOUN
bracis-19059	232	18	.	.	PUNCT
bracis-19059	233	1	hum	hum	ADJ
bracis-19059	233	2	.	.	PUNCT
bracis-19059	234	1	mutat	mutat	PROPN
bracis-19059	234	2	.	.	PUNCT
bracis-19059	235	1	27(2	27(2	NUM
bracis-19059	235	2	)	)	PUNCT
bracis-19059	235	3	,	,	PUNCT
bracis-19059	235	4	145–154	145–154	NUM
bracis-19059	235	5	(	(	PUNCT
bracis-19059	235	6	2006	2006	NUM
bracis-19059	235	7	)	)	PUNCT
bracis-19059	235	8	.	.	PUNCT
bracis-19059	236	1	https://doi.org/10.1002/humu.20280	https://doi.org/10.1002/humu.20280	ADJ
bracis-19059	236	2	article	article	NOUN
bracis-19059	236	3	  	  	SPACE
bracis-19059	236	4	google	google	PROPN
bracis-19059	236	5	scholar	scholar	NOUN
bracis-19059	236	6	  	  	SPACE
bracis-19059	236	7	bava	bava	PROPN
bracis-19059	236	8	,	,	PUNCT
bracis-19059	236	9	k.a	k.a	PROPN
bracis-19059	236	10	.	.	PROPN
bracis-19059	236	11	,	,	PUNCT
bracis-19059	236	12	gromiha	gromiha	PROPN
bracis-19059	236	13	,	,	PUNCT
bracis-19059	236	14	m.m	m.m	PROPN
bracis-19059	236	15	.	.	PROPN
bracis-19059	236	16	,	,	PUNCT
bracis-19059	236	17	uedaira	uedaira	PROPN
bracis-19059	236	18	,	,	PUNCT
bracis-19059	236	19	h.	h.	PROPN
bracis-19059	236	20	,	,	PUNCT
bracis-19059	236	21	kitajima	kitajima	PROPN
bracis-19059	236	22	,	,	PUNCT
bracis-19059	236	23	k.	k.	PROPN
bracis-19059	236	24	,	,	PUNCT
bracis-19059	236	25	sarai	sarai	PROPN
bracis-19059	236	26	,	,	PUNCT
bracis-19059	236	27	a.	a.	NOUN
bracis-19059	236	28	:	:	PUNCT
bracis-19059	236	29	protherm	protherm	NOUN
bracis-19059	236	30	,	,	PUNCT
bracis-19059	236	31	version	version	NOUN
bracis-19059	236	32	4.0	4.0	NUM
bracis-19059	236	33	:	:	PUNCT
bracis-19059	236	34	thermodynamic	thermodynamic	ADJ
bracis-19059	236	35	database	database	NOUN
bracis-19059	236	36	for	for	ADP
bracis-19059	236	37	proteins	protein	NOUN
bracis-19059	236	38	and	and	CCONJ
bracis-19059	236	39	mutants	mutant	NOUN
bracis-19059	236	40	.	.	PUNCT
bracis-19059	237	1	nucleic	nucleic	ADJ
bracis-19059	237	2	acids	acid	NOUN
bracis-19059	237	3	res	re	NOUN
bracis-19059	237	4	.	.	PUNCT
bracis-19059	238	1	32(1	32(1	NUM
bracis-19059	238	2	)	)	PUNCT
bracis-19059	238	3	,	,	PUNCT
bracis-19059	239	1	120–121	120–121	NUM
bracis-19059	239	2	(	(	PUNCT
bracis-19059	239	3	01	01	NUM
bracis-19059	239	4	2004	2004	NUM
bracis-19059	239	5	)	)	PUNCT
bracis-19059	239	6	.	.	PUNCT
bracis-19059	240	1	https://doi.org/10.1093/nar/gkh082	https://doi.org/10.1093/nar/gkh082	PROPN
bracis-19059	240	2	breiman	breiman	NOUN
bracis-19059	240	3	,	,	PUNCT
bracis-19059	240	4	l.	l.	PROPN
bracis-19059	240	5	:	:	PUNCT
bracis-19059	240	6	bagging	bag	VERB
bracis-19059	240	7	predictors	predictor	NOUN
bracis-19059	240	8	.	.	PUNCT
bracis-19059	241	1	mach	mach	NOUN
bracis-19059	241	2	.	.	PUNCT
bracis-19059	242	1	learn	learn	VERB
bracis-19059	242	2	.	.	PUNCT
bracis-19059	243	1	24(2	24(2	NUM
bracis-19059	243	2	)	)	PUNCT
bracis-19059	243	3	,	,	PUNCT
bracis-19059	243	4	123–140	123–140	NUM
bracis-19059	243	5	(	(	PUNCT
bracis-19059	243	6	1996	1996	NUM
bracis-19059	243	7	)	)	PUNCT
bracis-19059	243	8	math	math	NOUN
bracis-19059	243	9	  	  	SPACE
bracis-19059	243	10	google	google	PROPN
bracis-19059	243	11	scholar	scholar	NOUN
bracis-19059	243	12	  	  	SPACE
bracis-19059	243	13	capriotti	capriotti	NOUN
bracis-19059	243	14	,	,	PUNCT
bracis-19059	243	15	e.	e.	PROPN
bracis-19059	243	16	,	,	PUNCT
bracis-19059	243	17	fariselli	fariselli	PROPN
bracis-19059	243	18	,	,	PUNCT
bracis-19059	243	19	p.	p.	NOUN
bracis-19059	243	20	,	,	PUNCT
bracis-19059	243	21	casadio	casadio	PROPN
bracis-19059	243	22	,	,	PUNCT
bracis-19059	243	23	r.	r.	PROPN
bracis-19059	243	24	:	:	PUNCT
bracis-19059	243	25	a	a	DET
bracis-19059	243	26	neural	neural	ADJ
bracis-19059	243	27	-	-	PUNCT
bracis-19059	243	28	network	network	NOUN
bracis-19059	243	29	-	-	PUNCT
bracis-19059	243	30	based	base	VERB
bracis-19059	243	31	method	method	NOUN
bracis-19059	243	32	for	for	ADP
bracis-19059	243	33	predicting	predict	VERB
bracis-19059	243	34	protein	protein	NOUN
bracis-19059	243	35	stability	stability	NOUN
bracis-19059	243	36	changes	change	VERB
bracis-19059	243	37	upon	upon	SCONJ
bracis-19059	243	38	single	single	ADJ
bracis-19059	243	39	point	point	NOUN
bracis-19059	243	40	mutations	mutation	NOUN
bracis-19059	243	41	.	.	PUNCT
bracis-19059	244	1	bioinformatics	bioinformatics	NOUN
bracis-19059	244	2	20(suppl	20(suppl	NUM
bracis-19059	244	3	1	1	NUM
bracis-19059	244	4	)	)	PUNCT
bracis-19059	244	5	,	,	PUNCT
bracis-19059	244	6	i63	i63	NOUN
bracis-19059	244	7	–	–	PUNCT
bracis-19059	244	8	i68	i68	NOUN
bracis-19059	244	9	(	(	PUNCT
bracis-19059	244	10	2004	2004	NUM
bracis-19059	244	11	)	)	PUNCT
bracis-19059	244	12	.	.	PUNCT
bracis-19059	245	1	https://doi.org/10.1093/bioinformatics/bth928	https://doi.org/10.1093/bioinformatics/bth928	PROPN
bracis-19059	245	2	article	article	PROPN
bracis-19059	245	3	  	  	SPACE
bracis-19059	245	4	google	google	PROPN
bracis-19059	245	5	scholar	scholar	NOUN
bracis-19059	245	6	  	  	SPACE
bracis-19059	245	7	capriotti	capriotti	NOUN
bracis-19059	245	8	,	,	PUNCT
bracis-19059	245	9	e.	e.	PROPN
bracis-19059	245	10	,	,	PUNCT
bracis-19059	245	11	fariselli	fariselli	PROPN
bracis-19059	245	12	,	,	PUNCT
bracis-19059	245	13	p.	p.	PROPN
bracis-19059	245	14	,	,	PUNCT
bracis-19059	245	15	rossi	rossi	PROPN
bracis-19059	245	16	,	,	PUNCT
bracis-19059	245	17	i.	i.	PROPN
bracis-19059	245	18	,	,	PUNCT
bracis-19059	245	19	casadio	casadio	PROPN
bracis-19059	245	20	,	,	PUNCT
bracis-19059	245	21	r.	r.	PROPN
bracis-19059	245	22	:	:	PUNCT
bracis-19059	245	23	a	a	DET
bracis-19059	245	24	three	three	NUM
bracis-19059	245	25	-	-	PUNCT
bracis-19059	245	26	state	state	NOUN
bracis-19059	245	27	prediction	prediction	NOUN
bracis-19059	245	28	of	of	ADP
bracis-19059	245	29	single	single	ADJ
bracis-19059	245	30	point	point	NOUN
bracis-19059	245	31	mutations	mutation	NOUN
bracis-19059	245	32	on	on	ADP
bracis-19059	245	33	protein	protein	NOUN
bracis-19059	245	34	stability	stability	NOUN
bracis-19059	245	35	changes	change	NOUN
bracis-19059	245	36	.	.	PUNCT
bracis-19059	246	1	bmc	bmc	ADJ
bracis-19059	246	2	bioinform	bioinform	NOUN
bracis-19059	246	3	.	.	PUNCT
bracis-19059	247	1	9(suppl	9(suppl	NUM
bracis-19059	247	2	2	2	NUM
bracis-19059	247	3	)	)	PUNCT
bracis-19059	247	4	(	(	PUNCT
bracis-19059	247	5	2008	2008	NUM
bracis-19059	247	6	)	)	PUNCT
bracis-19059	247	7	.	.	PUNCT
bracis-19059	248	1	https://doi.org/10.1186/1471-2105-9-s2-s6	https://doi.org/10.1186/1471-2105-9-s2-s6	PROPN
bracis-19059	248	2	cheng	cheng	PROPN
bracis-19059	248	3	,	,	PUNCT
bracis-19059	248	4	j.	j.	PROPN
bracis-19059	248	5	,	,	PUNCT
bracis-19059	248	6	randall	randall	PROPN
bracis-19059	248	7	,	,	PUNCT
bracis-19059	248	8	a.	a.	PROPN
bracis-19059	248	9	,	,	PUNCT
bracis-19059	248	10	baldi	baldi	PROPN
bracis-19059	248	11	,	,	PUNCT
bracis-19059	248	12	p.	p.	NOUN
bracis-19059	248	13	:	:	PUNCT
bracis-19059	248	14	prediction	prediction	NOUN
bracis-19059	248	15	of	of	ADP
bracis-19059	248	16	protein	protein	NOUN
bracis-19059	248	17	stability	stability	NOUN
bracis-19059	248	18	changes	change	VERB
bracis-19059	248	19	for	for	ADP
bracis-19059	248	20	single	single	ADJ
bracis-19059	248	21	-	-	PUNCT
bracis-19059	248	22	site	site	NOUN
bracis-19059	248	23	mutations	mutation	NOUN
bracis-19059	248	24	using	use	VERB
bracis-19059	248	25	support	support	NOUN
bracis-19059	248	26	vector	vector	NOUN
bracis-19059	248	27	machines	machine	NOUN
bracis-19059	248	28	.	.	PUNCT
bracis-19059	249	1	prot	prot	NOUN
bracis-19059	249	2	.	.	PUNCT
bracis-19059	249	3	struct	struct	NOUN
bracis-19059	249	4	.	.	PUNCT
bracis-19059	250	1	function	function	NOUN
bracis-19059	250	2	bioinform	bioinform	NOUN
bracis-19059	250	3	.	.	PUNCT
bracis-19059	251	1	62(4	62(4	X
bracis-19059	251	2	)	)	PUNCT
bracis-19059	251	3	,	,	PUNCT
bracis-19059	251	4	1125–1132	1125–1132	NUM
bracis-19059	251	5	(	(	PUNCT
bracis-19059	251	6	2005	2005	NUM
bracis-19059	251	7	)	)	PUNCT
bracis-19059	251	8	.	.	PUNCT
bracis-19059	252	1	https://doi.org/10.1002/prot.20810	https://doi.org/10.1002/prot.20810	NOUN
bracis-19059	252	2	dehouck	dehouck	VERB
bracis-19059	252	3	,	,	PUNCT
bracis-19059	252	4	y.	y.	PROPN
bracis-19059	252	5	,	,	PUNCT
bracis-19059	252	6	kwasigroch	kwasigroch	PROPN
bracis-19059	252	7	,	,	PUNCT
bracis-19059	252	8	j.m	j.m	PROPN
bracis-19059	252	9	.	.	PROPN
bracis-19059	252	10	,	,	PUNCT
bracis-19059	252	11	gilis	gilis	PROPN
bracis-19059	252	12	,	,	PUNCT
bracis-19059	252	13	d.	d.	PROPN
bracis-19059	252	14	,	,	PUNCT
bracis-19059	252	15	rooman	rooman	NOUN
bracis-19059	252	16	,	,	PUNCT
bracis-19059	252	17	m.	m.	NOUN
bracis-19059	252	18	:	:	PUNCT
bracis-19059	252	19	popmusic	popmusic	ADJ
bracis-19059	252	20	2.1	2.1	NUM
bracis-19059	252	21	:	:	PUNCT
bracis-19059	252	22	a	a	DET
bracis-19059	252	23	web	web	NOUN
bracis-19059	252	24	server	server	NOUN
bracis-19059	252	25	for	for	ADP
bracis-19059	252	26	the	the	DET
bracis-19059	252	27	estimation	estimation	NOUN
bracis-19059	252	28	of	of	ADP
bracis-19059	252	29	protein	protein	NOUN
bracis-19059	252	30	stability	stability	NOUN
bracis-19059	252	31	changes	change	VERB
bracis-19059	252	32	upon	upon	SCONJ
bracis-19059	252	33	mutation	mutation	NOUN
bracis-19059	252	34	and	and	CCONJ
bracis-19059	252	35	sequence	sequence	NOUN
bracis-19059	252	36	optimality	optimality	NOUN
bracis-19059	252	37	.	.	PUNCT
bracis-19059	253	1	bmc	bmc	NOUN
bracis-19059	253	2	bioinform	bioinform	NOUN
bracis-19059	253	3	.	.	PUNCT
bracis-19059	254	1	12(1	12(1	NUM
bracis-19059	254	2	)	)	PUNCT
bracis-19059	254	3	(	(	PUNCT
bracis-19059	254	4	2011	2011	NUM
bracis-19059	254	5	)	)	PUNCT
bracis-19059	254	6	.	.	PUNCT
bracis-19059	255	1	https://doi.org/10.1186/1471-2105-12-151	https://doi.org/10.1186/1471-2105-12-151	ADP
bracis-19059	255	2	dong	dong	NOUN
bracis-19059	255	3	,	,	PUNCT
bracis-19059	255	4	x.	x.	PROPN
bracis-19059	255	5	,	,	PUNCT
bracis-19059	255	6	yu	yu	PROPN
bracis-19059	255	7	,	,	PUNCT
bracis-19059	255	8	z.	z.	PROPN
bracis-19059	255	9	,	,	PUNCT
bracis-19059	255	10	cao	cao	PROPN
bracis-19059	255	11	,	,	PUNCT
bracis-19059	255	12	w.	w.	PROPN
bracis-19059	255	13	,	,	PUNCT
bracis-19059	255	14	shi	shi	PROPN
bracis-19059	255	15	,	,	PUNCT
bracis-19059	255	16	y.	y.	PROPN
bracis-19059	255	17	,	,	PUNCT
bracis-19059	255	18	ma	ma	PROPN
bracis-19059	255	19	,	,	PUNCT
bracis-19059	255	20	q.	q.	PROPN
bracis-19059	255	21	:	:	PUNCT
bracis-19059	255	22	a	a	DET
bracis-19059	255	23	survey	survey	NOUN
bracis-19059	255	24	on	on	ADP
bracis-19059	255	25	ensemble	ensemble	ADJ
bracis-19059	255	26	learning	learning	NOUN
bracis-19059	255	27	.	.	PUNCT
bracis-19059	256	1	front	front	ADJ
bracis-19059	256	2	.	.	PUNCT
bracis-19059	257	1	comput	comput	NOUN
bracis-19059	257	2	.	.	PUNCT
bracis-19059	258	1	sci	sci	PROPN
bracis-19059	258	2	.	.	PUNCT
bracis-19059	259	1	14(2	14(2	NUM
bracis-19059	259	2	)	)	PUNCT
bracis-19059	260	1	,	,	PUNCT
bracis-19059	260	2	241–258	241–258	NUM
bracis-19059	260	3	(	(	PUNCT
bracis-19059	260	4	2020	2020	NUM
bracis-19059	260	5	)	)	PUNCT
bracis-19059	260	6	article	article	NOUN
bracis-19059	260	7	  	  	SPACE
bracis-19059	260	8	google	google	PROPN
bracis-19059	260	9	scholar	scholar	NOUN
bracis-19059	260	10	  	  	SPACE
bracis-19059	260	11	eickholt	eickholt	NOUN
bracis-19059	260	12	,	,	PUNCT
bracis-19059	260	13	j.	j.	PROPN
bracis-19059	260	14	,	,	PUNCT
bracis-19059	260	15	cheng	cheng	PROPN
bracis-19059	260	16	,	,	PUNCT
bracis-19059	260	17	j.	j.	PROPN
bracis-19059	260	18	:	:	PUNCT
bracis-19059	260	19	dndisorder	dndisorder	NOUN
bracis-19059	260	20	:	:	PUNCT
bracis-19059	260	21	predicting	predict	VERB
bracis-19059	260	22	protein	protein	NOUN
bracis-19059	260	23	disorder	disorder	NOUN
bracis-19059	260	24	using	use	VERB
bracis-19059	260	25	boosting	boost	VERB
bracis-19059	260	26	and	and	CCONJ
bracis-19059	260	27	deep	deep	ADJ
bracis-19059	260	28	networks	network	NOUN
bracis-19059	260	29	.	.	PUNCT
bracis-19059	261	1	bmc	bmc	ADJ
bracis-19059	261	2	bioinform	bioinform	NOUN
bracis-19059	261	3	.	.	PUNCT
bracis-19059	262	1	14(1	14(1	NUM
bracis-19059	262	2	)	)	PUNCT
bracis-19059	262	3	,	,	PUNCT
bracis-19059	262	4	1	1	NUM
bracis-19059	262	5	(	(	PUNCT
bracis-19059	262	6	2013	2013	NUM
bracis-19059	262	7	)	)	PUNCT
bracis-19059	262	8	article	article	NOUN
bracis-19059	262	9	  	  	SPACE
bracis-19059	262	10	google	google	PROPN
bracis-19059	262	11	scholar	scholar	NOUN
bracis-19059	262	12	  	  	SPACE
bracis-19059	262	13	fersht	fersht	NOUN
bracis-19059	262	14	,	,	PUNCT
bracis-19059	262	15	a.r	a.r	PROPN
bracis-19059	262	16	.	.	PROPN
bracis-19059	262	17	:	:	PUNCT
bracis-19059	263	1	protein	protein	NOUN
bracis-19059	263	2	folding	folding	NOUN
bracis-19059	263	3	and	and	CCONJ
bracis-19059	263	4	stability	stability	NOUN
bracis-19059	263	5	:	:	PUNCT
bracis-19059	263	6	the	the	DET
bracis-19059	263	7	pathway	pathway	NOUN
bracis-19059	263	8	of	of	ADP
bracis-19059	263	9	folding	folding	NOUN
bracis-19059	263	10	of	of	ADP
bracis-19059	263	11	barnase	barnase	NOUN
bracis-19059	263	12	.	.	PUNCT
bracis-19059	264	1	febs	febs	PROPN
bracis-19059	264	2	lett	lett	PROPN
bracis-19059	264	3	.	.	PUNCT
bracis-19059	265	1	325(1–2	325(1–2	NUM
bracis-19059	265	2	)	)	PUNCT
bracis-19059	265	3	,	,	PUNCT
bracis-19059	265	4	5–16	5–16	PROPN
bracis-19059	265	5	(	(	PUNCT
bracis-19059	265	6	1993	1993	NUM
bracis-19059	265	7	)	)	PUNCT
bracis-19059	265	8	google	google	NOUN
bracis-19059	265	9	scholar	scholar	NOUN
bracis-19059	265	10	  	  	SPACE
bracis-19059	265	11	freund	freund	NOUN
bracis-19059	265	12	,	,	PUNCT
bracis-19059	265	13	y.	y.	NOUN
bracis-19059	265	14	,	,	PUNCT
bracis-19059	265	15	schapire	schapire	NOUN
bracis-19059	265	16	,	,	PUNCT
bracis-19059	265	17	r.e	r.e	PROPN
bracis-19059	265	18	.	.	PROPN
bracis-19059	265	19	,	,	PUNCT
bracis-19059	265	20	et	et	PROPN
bracis-19059	265	21	al	al	PROPN
bracis-19059	265	22	.	.	PUNCT
bracis-19059	265	23	:	:	PUNCT
bracis-19059	266	1	experiments	experiment	NOUN
bracis-19059	266	2	with	with	ADP
bracis-19059	266	3	a	a	DET
bracis-19059	266	4	new	new	ADJ
bracis-19059	266	5	boosting	boost	VERB
bracis-19059	266	6	algorithm	algorithm	NOUN
bracis-19059	266	7	.	.	PUNCT
bracis-19059	267	1	in	in	ADP
bracis-19059	267	2	:	:	PUNCT
bracis-19059	267	3	icml	icml	NOUN
bracis-19059	267	4	,	,	PUNCT
bracis-19059	267	5	vol	vol	NOUN
bracis-19059	267	6	.	.	PROPN
bracis-19059	267	7	96	96	NUM
bracis-19059	267	8	,	,	PUNCT
bracis-19059	267	9	pp	pp	ADJ
bracis-19059	267	10	.	.	PUNCT
bracis-19059	268	1	148–156	148–156	NUM
bracis-19059	268	2	(	(	PUNCT
bracis-19059	268	3	1996	1996	NUM
bracis-19059	268	4	)	)	PUNCT
bracis-19059	268	5	google	google	PROPN
bracis-19059	268	6	scholar	scholar	NOUN
bracis-19059	268	7	  	  	SPACE
bracis-19059	268	8	guerois	guerois	NOUN
bracis-19059	268	9	,	,	PUNCT
bracis-19059	268	10	r.	r.	PROPN
bracis-19059	268	11	,	,	PUNCT
bracis-19059	268	12	nielsen	nielsen	PROPN
bracis-19059	268	13	,	,	PUNCT
bracis-19059	268	14	j.e	j.e	PROPN
bracis-19059	268	15	.	.	PROPN
bracis-19059	268	16	,	,	PUNCT
bracis-19059	268	17	serrano	serrano	PROPN
bracis-19059	268	18	,	,	PUNCT
bracis-19059	268	19	l.	l.	PROPN
bracis-19059	268	20	:	:	PUNCT
bracis-19059	268	21	predicting	predict	VERB
bracis-19059	268	22	changes	change	NOUN
bracis-19059	268	23	in	in	ADP
bracis-19059	268	24	the	the	DET
bracis-19059	268	25	stability	stability	NOUN
bracis-19059	268	26	of	of	ADP
bracis-19059	268	27	proteins	protein	NOUN
bracis-19059	268	28	and	and	CCONJ
bracis-19059	268	29	protein	protein	NOUN
bracis-19059	268	30	complexes	complex	NOUN
bracis-19059	268	31	:	:	PUNCT
bracis-19059	268	32	a	a	DET
bracis-19059	268	33	study	study	NOUN
bracis-19059	268	34	of	of	ADP
bracis-19059	268	35	more	more	ADJ
bracis-19059	268	36	than	than	ADP
bracis-19059	268	37	1000	1000	NUM
bracis-19059	268	38	mutations	mutation	NOUN
bracis-19059	268	39	.	.	PUNCT
bracis-19059	269	1	j.	j.	PROPN
bracis-19059	269	2	mol	mol	PROPN
bracis-19059	269	3	.	.	PUNCT
bracis-19059	270	1	biol	biol	PROPN
bracis-19059	270	2	.	.	PUNCT
bracis-19059	271	1	320(2	320(2	NUM
bracis-19059	271	2	)	)	PUNCT
bracis-19059	271	3	,	,	PUNCT
bracis-19059	271	4	369–387	369–387	NUM
bracis-19059	271	5	(	(	PUNCT
bracis-19059	271	6	2002	2002	NUM
bracis-19059	271	7	)	)	PUNCT
bracis-19059	271	8	.	.	PUNCT
bracis-19059	272	1	https://doi.org/10.1016/s0022-2836(02)00442-4	https://doi.org/10.1016/s0022-2836(02)00442-4	PROPN
bracis-19059	272	2	article	article	NOUN
bracis-19059	272	3	  	  	SPACE
bracis-19059	272	4	google	google	PROPN
bracis-19059	272	5	scholar	scholar	NOUN
bracis-19059	272	6	  	  	SPACE
bracis-19059	272	7	han	han	PROPN
bracis-19059	272	8	,	,	PUNCT
bracis-19059	272	9	j.	j.	PROPN
bracis-19059	272	10	,	,	PUNCT
bracis-19059	272	11	pei	pei	PROPN
bracis-19059	272	12	,	,	PUNCT
bracis-19059	272	13	j.	j.	PROPN
bracis-19059	272	14	,	,	PUNCT
bracis-19059	272	15	kamber	kamber	PROPN
bracis-19059	272	16	,	,	PUNCT
bracis-19059	272	17	m.	m.	NOUN
bracis-19059	272	18	:	:	PUNCT
bracis-19059	272	19	data	datum	NOUN
bracis-19059	272	20	mining	mining	NOUN
bracis-19059	272	21	concepts	concept	NOUN
bracis-19059	272	22	and	and	CCONJ
bracis-19059	272	23	techniques	technique	NOUN
bracis-19059	272	24	.	.	PUNCT
bracis-19059	273	1	morgan	morgan	PROPN
bracis-19059	273	2	and	and	CCONJ
bracis-19059	273	3	kaufmann	kaufmann	PROPN
bracis-19059	273	4	,	,	PUNCT
bracis-19059	273	5	san	san	PROPN
bracis-19059	273	6	francisco	francisco	PROPN
bracis-19059	273	7	(	(	PUNCT
bracis-19059	273	8	2006	2006	NUM
bracis-19059	273	9	)	)	PUNCT
bracis-19059	273	10	math	math	NOUN
bracis-19059	273	11	  	  	SPACE
bracis-19059	273	12	google	google	PROPN
bracis-19059	273	13	scholar	scholar	NOUN
bracis-19059	273	14	  	  	SPACE
bracis-19059	273	15	laimer	laimer	NOUN
bracis-19059	273	16	,	,	PUNCT
bracis-19059	273	17	j.	j.	PROPN
bracis-19059	273	18	,	,	PUNCT
bracis-19059	273	19	hofer	hofer	PROPN
bracis-19059	273	20	,	,	PUNCT
bracis-19059	273	21	h.	h.	PROPN
bracis-19059	273	22	,	,	PUNCT
bracis-19059	273	23	fritz	fritz	PROPN
bracis-19059	273	24	,	,	PUNCT
bracis-19059	273	25	m.	m.	NOUN
bracis-19059	273	26	,	,	PUNCT
bracis-19059	273	27	wegenkittl	wegenkittl	PROPN
bracis-19059	273	28	,	,	PUNCT
bracis-19059	273	29	s.	s.	PROPN
bracis-19059	273	30	,	,	PUNCT
bracis-19059	273	31	lackner	lackner	NOUN
bracis-19059	273	32	,	,	PUNCT
bracis-19059	273	33	p.	p.	NOUN
bracis-19059	273	34	:	:	PUNCT
bracis-19059	273	35	maestro	maestro	PROPN
bracis-19059	273	36	multi	multi	ADJ
bracis-19059	273	37	agent	agent	NOUN
bracis-19059	273	38	stability	stability	NOUN
bracis-19059	273	39	prediction	prediction	NOUN
bracis-19059	273	40	upon	upon	SCONJ
bracis-19059	273	41	point	point	NOUN
bracis-19059	273	42	mutations	mutation	NOUN
bracis-19059	273	43	.	.	PUNCT
bracis-19059	274	1	bmc	bmc	ADJ
bracis-19059	274	2	bioinform	bioinform	NOUN
bracis-19059	274	3	.	.	PUNCT
bracis-19059	275	1	16(1	16(1	X
bracis-19059	275	2	)	)	PUNCT
bracis-19059	275	3	(	(	PUNCT
bracis-19059	275	4	2015	2015	NUM
bracis-19059	275	5	)	)	PUNCT
bracis-19059	275	6	.	.	PUNCT
bracis-19059	276	1	https://doi.org/10.1186/s12859-015-0548-6	https://doi.org/10.1186/s12859-015-0548-6	PROPN
bracis-19059	276	2	mendoza	mendoza	PROPN
bracis-19059	276	3	,	,	PUNCT
bracis-19059	276	4	m.r	m.r	PROPN
bracis-19059	276	5	.	.	PROPN
bracis-19059	276	6	,	,	PUNCT
bracis-19059	276	7	bazzan	bazzan	NOUN
bracis-19059	276	8	,	,	PUNCT
bracis-19059	276	9	a.l.c	a.l.c	NOUN
bracis-19059	276	10	.	.	PUNCT
bracis-19059	276	11	:	:	PUNCT
bracis-19059	277	1	the	the	DET
bracis-19059	277	2	wisdom	wisdom	NOUN
bracis-19059	277	3	of	of	ADP
bracis-19059	277	4	crowds	crowd	NOUN
bracis-19059	277	5	in	in	ADP
bracis-19059	277	6	bioinformatics	bioinformatics	NOUN
bracis-19059	277	7	:	:	PUNCT
bracis-19059	277	8	what	what	PRON
bracis-19059	277	9	can	can	AUX
bracis-19059	277	10	we	we	PRON
bracis-19059	277	11	learn	learn	VERB
bracis-19059	277	12	(	(	PUNCT
bracis-19059	277	13	and	and	CCONJ
bracis-19059	277	14	gain	gain	VERB
bracis-19059	277	15	)	)	PUNCT
bracis-19059	277	16	from	from	ADP
bracis-19059	277	17	ensemble	ensemble	ADJ
bracis-19059	277	18	predictions	prediction	NOUN
bracis-19059	277	19	?	?	PUNCT
bracis-19059	278	1	in	in	ADP
bracis-19059	278	2	:	:	PUNCT
bracis-19059	278	3	proceedings	proceeding	NOUN
bracis-19059	278	4	of	of	ADP
bracis-19059	278	5	the	the	DET
bracis-19059	278	6	twenty	twenty	NUM
bracis-19059	278	7	-	-	PUNCT
bracis-19059	278	8	seventh	seventh	ADJ
bracis-19059	278	9	aaai	aaai	PROPN
bracis-19059	278	10	conference	conference	NOUN
bracis-19059	278	11	on	on	ADP
bracis-19059	278	12	artificial	artificial	ADJ
bracis-19059	278	13	intelligence	intelligence	NOUN
bracis-19059	278	14	,	,	PUNCT
bracis-19059	278	15	pp	pp	ADJ
bracis-19059	278	16	.	.	PUNCT
bracis-19059	279	1	1678–1679	1678–1679	NUM
bracis-19059	279	2	(	(	PUNCT
bracis-19059	279	3	2013	2013	NUM
bracis-19059	279	4	)	)	PUNCT
bracis-19059	279	5	google	google	PROPN
bracis-19059	279	6	scholar	scholar	NOUN
bracis-19059	279	7	  	  	SPACE
bracis-19059	279	8	noçairi	noçairi	PROPN
bracis-19059	279	9	,	,	PUNCT
bracis-19059	279	10	h.	h.	PROPN
bracis-19059	279	11	,	,	PUNCT
bracis-19059	279	12	gomes	gomes	PROPN
bracis-19059	279	13	,	,	PUNCT
bracis-19059	279	14	c.	c.	PROPN
bracis-19059	279	15	,	,	PUNCT
bracis-19059	279	16	thomas	thomas	PROPN
bracis-19059	279	17	,	,	PUNCT
bracis-19059	279	18	m.	m.	NOUN
bracis-19059	279	19	,	,	PUNCT
bracis-19059	279	20	saporta	saporta	PROPN
bracis-19059	279	21	,	,	PUNCT
bracis-19059	279	22	g.	g.	PROPN
bracis-19059	279	23	:	:	PUNCT
bracis-19059	279	24	improving	improve	VERB
bracis-19059	279	25	stacking	stack	VERB
bracis-19059	279	26	methodology	methodology	NOUN
bracis-19059	279	27	for	for	ADP
bracis-19059	279	28	combining	combine	VERB
bracis-19059	279	29	classifiers	classifier	NOUN
bracis-19059	279	30	;	;	PUNCT
bracis-19059	279	31	applications	application	NOUN
bracis-19059	279	32	to	to	ADP
bracis-19059	279	33	cosmetic	cosmetic	ADJ
bracis-19059	279	34	industry	industry	NOUN
bracis-19059	279	35	.	.	PUNCT
bracis-19059	280	1	electron	electron	PROPN
bracis-19059	280	2	.	.	PUNCT
bracis-19059	281	1	j.	j.	PROPN
bracis-19059	281	2	appl	appl	PROPN
bracis-19059	281	3	.	.	PROPN
bracis-19059	282	1	stat	stat	PROPN
bracis-19059	282	2	.	.	PUNCT
bracis-19059	283	1	anal	anal	ADJ
bracis-19059	283	2	.	.	PUNCT
bracis-19059	284	1	9(2	9(2	NUM
bracis-19059	284	2	)	)	PUNCT
bracis-19059	284	3	,	,	PUNCT
bracis-19059	284	4	340–361	340–361	NUM
bracis-19059	284	5	(	(	PUNCT
bracis-19059	284	6	2016	2016	NUM
bracis-19059	284	7	)	)	PUNCT
bracis-19059	284	8	mathscinet	mathscinet	NOUN
bracis-19059	284	9	  	  	SPACE
bracis-19059	284	10	google	google	PROPN
bracis-19059	284	11	scholar	scholar	NOUN
bracis-19059	284	12	  	  	SPACE
bracis-19059	284	13	parthiban	parthiban	NOUN
bracis-19059	284	14	,	,	PUNCT
bracis-19059	284	15	v.	v.	ADV
bracis-19059	284	16	,	,	PUNCT
bracis-19059	284	17	gromiha	gromiha	NOUN
bracis-19059	284	18	,	,	PUNCT
bracis-19059	284	19	m.m	m.m	PROPN
bracis-19059	284	20	.	.	PROPN
bracis-19059	284	21	,	,	PUNCT
bracis-19059	284	22	schomburg	schomburg	PROPN
bracis-19059	284	23	,	,	PUNCT
bracis-19059	284	24	d.	d.	PROPN
bracis-19059	284	25	:	:	PUNCT
bracis-19059	284	26	cupsat	cupsat	VERB
bracis-19059	284	27	:	:	PUNCT
bracis-19059	284	28	prediction	prediction	NOUN
bracis-19059	284	29	of	of	ADP
bracis-19059	284	30	protein	protein	NOUN
bracis-19059	284	31	stability	stability	NOUN
bracis-19059	284	32	upon	upon	SCONJ
bracis-19059	284	33	point	point	NOUN
bracis-19059	284	34	mutations	mutation	NOUN
bracis-19059	284	35	.	.	PUNCT
bracis-19059	285	1	nucl	nucl	PROPN
bracis-19059	285	2	.	.	PUNCT
bracis-19059	286	1	acids	acid	NOUN
bracis-19059	286	2	res	re	NOUN
bracis-19059	286	3	.	.	PUNCT
bracis-19059	287	1	34(web	34(web	NUM
bracis-19059	287	2	server	server	NOUN
bracis-19059	287	3	)	)	PUNCT
bracis-19059	287	4	,	,	PUNCT
bracis-19059	287	5	january	january	PROPN
bracis-19059	287	6	2006	2006	NUM
bracis-19059	287	7	.	.	PUNCT
bracis-19059	288	1	https://doi.org/10.1093/nar/gkl190	https://doi.org/10.1093/nar/gkl190	VERB
bracis-19059	288	2	pires	pire	NOUN
bracis-19059	288	3	,	,	PUNCT
bracis-19059	288	4	d.e.v	d.e.v	INTJ
bracis-19059	288	5	.	.	PROPN
bracis-19059	288	6	,	,	PUNCT
bracis-19059	288	7	ascher	ascher	PROPN
bracis-19059	288	8	,	,	PUNCT
bracis-19059	288	9	d.b	d.b	PROPN
bracis-19059	288	10	.	.	PROPN
bracis-19059	288	11	,	,	PUNCT
bracis-19059	288	12	blundell	blundell	PROPN
bracis-19059	288	13	,	,	PUNCT
bracis-19059	288	14	t.l	t.l	PROPN
bracis-19059	288	15	.	.	PUNCT
bracis-19059	288	16	:	:	PUNCT
bracis-19059	289	1	mcsm	mcsm	NOUN
bracis-19059	289	2	:	:	PUNCT
bracis-19059	289	3	predicting	predict	VERB
bracis-19059	289	4	the	the	DET
bracis-19059	289	5	effects	effect	NOUN
bracis-19059	289	6	of	of	ADP
bracis-19059	289	7	mutations	mutation	NOUN
bracis-19059	289	8	in	in	ADP
bracis-19059	289	9	proteins	protein	NOUN
bracis-19059	289	10	using	use	VERB
bracis-19059	289	11	graph	graph	NOUN
bracis-19059	289	12	-	-	PUNCT
bracis-19059	289	13	based	base	VERB
bracis-19059	289	14	signatures	signature	NOUN
bracis-19059	289	15	.	.	PUNCT
bracis-19059	290	1	bioinformatics	bioinformatics	NOUN
bracis-19059	290	2	30(3	30(3	NOUN
bracis-19059	290	3	)	)	PUNCT
bracis-19059	290	4	,	,	PUNCT
bracis-19059	290	5	335–342	335–342	NUM
bracis-19059	290	6	(	(	PUNCT
bracis-19059	290	7	2013	2013	NUM
bracis-19059	290	8	)	)	PUNCT
bracis-19059	290	9	.	.	PUNCT
bracis-19059	291	1	https://doi.org/10.1093/bioinformatics/btt691	https://doi.org/10.1093/bioinformatics/btt691	PROPN
bracis-19059	291	2	article	article	NOUN
bracis-19059	291	3	  	  	SPACE
bracis-19059	291	4	google	google	PROPN
bracis-19059	291	5	scholar	scholar	NOUN
bracis-19059	291	6	  	  	SPACE
bracis-19059	291	7	pires	pire	NOUN
bracis-19059	291	8	,	,	PUNCT
bracis-19059	291	9	d.e	d.e	PROPN
bracis-19059	291	10	.	.	PROPN
bracis-19059	291	11	,	,	PUNCT
bracis-19059	291	12	ascher	ascher	PROPN
bracis-19059	291	13	,	,	PUNCT
bracis-19059	291	14	d.b	d.b	PROPN
bracis-19059	291	15	.	.	PROPN
bracis-19059	291	16	,	,	PUNCT
bracis-19059	291	17	blundell	blundell	PROPN
bracis-19059	291	18	,	,	PUNCT
bracis-19059	291	19	t.l	t.l	PROPN
bracis-19059	291	20	.	.	PUNCT
bracis-19059	291	21	:	:	PUNCT
bracis-19059	292	1	duet	duet	NOUN
bracis-19059	292	2	:	:	PUNCT
bracis-19059	292	3	a	a	DET
bracis-19059	292	4	server	server	NOUN
bracis-19059	292	5	for	for	ADP
bracis-19059	292	6	predicting	predict	VERB
bracis-19059	292	7	effects	effect	NOUN
bracis-19059	292	8	of	of	ADP
bracis-19059	292	9	mutations	mutation	NOUN
bracis-19059	292	10	on	on	ADP
bracis-19059	292	11	protein	protein	NOUN
bracis-19059	292	12	stability	stability	NOUN
bracis-19059	292	13	using	use	VERB
bracis-19059	292	14	an	an	DET
bracis-19059	292	15	integrated	integrated	ADJ
bracis-19059	292	16	computational	computational	ADJ
bracis-19059	292	17	approach	approach	NOUN
bracis-19059	292	18	.	.	PUNCT
bracis-19059	293	1	nucl	nucl	PROPN
bracis-19059	293	2	.	.	PUNCT
bracis-19059	294	1	acids	acid	NOUN
bracis-19059	294	2	res	re	NOUN
bracis-19059	294	3	.	.	PUNCT
bracis-19059	295	1	42(w1	42(w1	NUM
bracis-19059	295	2	)	)	PUNCT
bracis-19059	296	1	,	,	PUNCT
bracis-19059	296	2	w314	w314	PROPN
bracis-19059	296	3	–	–	PUNCT
bracis-19059	296	4	w319	w319	PROPN
bracis-19059	296	5	(	(	PUNCT
bracis-19059	296	6	2014	2014	NUM
bracis-19059	296	7	)	)	PUNCT
bracis-19059	296	8	article	article	NOUN
bracis-19059	296	9	  	  	SPACE
bracis-19059	296	10	google	google	PROPN
bracis-19059	296	11	scholar	scholar	NOUN
bracis-19059	296	12	  	  	SPACE
bracis-19059	296	13	saha	saha	PROPN
bracis-19059	296	14	,	,	PUNCT
bracis-19059	296	15	i.	i.	PROPN
bracis-19059	296	16	,	,	PUNCT
bracis-19059	296	17	zubek	zubek	PROPN
bracis-19059	296	18	,	,	PUNCT
bracis-19059	296	19	j.	j.	PROPN
bracis-19059	296	20	,	,	PUNCT
bracis-19059	296	21	klingström	klingström	NOUN
bracis-19059	296	22	,	,	PUNCT
bracis-19059	296	23	t.	t.	PROPN
bracis-19059	296	24	,	,	PUNCT
bracis-19059	296	25	forsberg	forsberg	PROPN
bracis-19059	296	26	,	,	PUNCT
bracis-19059	296	27	s.	s.	PROPN
bracis-19059	296	28	,	,	PUNCT
bracis-19059	296	29	wikander	wikander	PROPN
bracis-19059	296	30	,	,	PUNCT
bracis-19059	296	31	j.	j.	PROPN
bracis-19059	296	32	,	,	PUNCT
bracis-19059	296	33	kierczak	kierczak	NOUN
bracis-19059	296	34	,	,	PUNCT
bracis-19059	296	35	m.	m.	NOUN
bracis-19059	296	36	,	,	PUNCT
bracis-19059	296	37	maulik	maulik	NOUN
bracis-19059	296	38	,	,	PUNCT
bracis-19059	296	39	u.	u.	PROPN
bracis-19059	296	40	,	,	PUNCT
bracis-19059	296	41	plewczynski	plewczynski	NOUN
bracis-19059	296	42	,	,	PUNCT
bracis-19059	296	43	d.	d.	PROPN
bracis-19059	296	44	:	:	PUNCT
bracis-19059	296	45	ensemble	ensemble	ADJ
bracis-19059	296	46	learning	learning	NOUN
bracis-19059	296	47	prediction	prediction	NOUN
bracis-19059	296	48	of	of	ADP
bracis-19059	296	49	protein	protein	NOUN
bracis-19059	296	50	-	-	PUNCT
bracis-19059	296	51	protein	protein	NOUN
bracis-19059	296	52	interactions	interaction	NOUN
bracis-19059	296	53	using	use	VERB
bracis-19059	296	54	proteins	protein	NOUN
bracis-19059	296	55	functional	functional	ADJ
bracis-19059	296	56	annotations	annotation	NOUN
bracis-19059	296	57	.	.	PUNCT
bracis-19059	297	1	mol	mol	PROPN
bracis-19059	297	2	.	.	PUNCT
bracis-19059	297	3	biosyst	biosyst	PROPN
bracis-19059	297	4	.	.	PUNCT
bracis-19059	298	1	10(4	10(4	X
bracis-19059	298	2	)	)	PUNCT
bracis-19059	298	3	,	,	PUNCT
bracis-19059	298	4	820–830	820–830	NUM
bracis-19059	298	5	(	(	PUNCT
bracis-19059	298	6	2014	2014	NUM
bracis-19059	298	7	)	)	PUNCT
bracis-19059	298	8	article	article	NOUN
bracis-19059	298	9	  	  	SPACE
bracis-19059	298	10	google	google	PROPN
bracis-19059	298	11	scholar	scholar	NOUN
bracis-19059	298	12	  	  	SPACE
bracis-19059	298	13	sugita	sugita	NOUN
bracis-19059	298	14	,	,	PUNCT
bracis-19059	298	15	y.	y.	PROPN
bracis-19059	298	16	,	,	PUNCT
bracis-19059	298	17	kitao	kitao	PROPN
bracis-19059	298	18	,	,	PUNCT
bracis-19059	298	19	a.	a.	NOUN
bracis-19059	298	20	:	:	PUNCT
bracis-19059	298	21	dependence	dependence	NOUN
bracis-19059	298	22	of	of	ADP
bracis-19059	298	23	protein	protein	NOUN
bracis-19059	298	24	stability	stability	NOUN
bracis-19059	298	25	on	on	ADP
bracis-19059	298	26	the	the	DET
bracis-19059	298	27	structure	structure	NOUN
bracis-19059	298	28	of	of	ADP
bracis-19059	298	29	the	the	DET
bracis-19059	298	30	denatured	denatured	ADJ
bracis-19059	298	31	state	state	NOUN
bracis-19059	298	32	:	:	PUNCT
bracis-19059	298	33	free	free	ADJ
bracis-19059	298	34	energy	energy	NOUN
bracis-19059	298	35	calculations	calculation	NOUN
bracis-19059	298	36	of	of	ADP
bracis-19059	298	37	i56v	i56v	PROPN
bracis-19059	298	38	mutation	mutation	NOUN
bracis-19059	298	39	in	in	ADP
bracis-19059	298	40	human	human	ADJ
bracis-19059	298	41	lysozyme	lysozyme	NOUN
bracis-19059	298	42	.	.	PUNCT
bracis-19059	299	1	biophys	biophy	NOUN
bracis-19059	299	2	.	.	PUNCT
bracis-19059	300	1	j.	j.	PROPN
bracis-19059	300	2	75(5	75(5	PROPN
bracis-19059	300	3	)	)	PUNCT
bracis-19059	300	4	,	,	PUNCT
bracis-19059	300	5	2178–2187	2178–2187	NUM
bracis-19059	300	6	(	(	PUNCT
bracis-19059	300	7	1998	1998	NUM
bracis-19059	300	8	)	)	PUNCT
bracis-19059	300	9	article	article	NOUN
bracis-19059	300	10	  	  	SPACE
bracis-19059	300	11	google	google	PROPN
bracis-19059	300	12	scholar	scholar	NOUN
bracis-19059	300	13	  	  	SPACE
bracis-19059	300	14	tan	tan	PROPN
bracis-19059	300	15	,	,	PUNCT
bracis-19059	300	16	p.n	p.n	PROPN
bracis-19059	300	17	.	.	PROPN
bracis-19059	300	18	,	,	PUNCT
bracis-19059	300	19	steinbach	steinbach	PROPN
bracis-19059	300	20	,	,	PUNCT
bracis-19059	300	21	m.	m.	NOUN
bracis-19059	300	22	,	,	PUNCT
bracis-19059	300	23	kumar	kumar	PROPN
bracis-19059	300	24	,	,	PUNCT
bracis-19059	300	25	v.	v.	NOUN
bracis-19059	300	26	:	:	PUNCT
bracis-19059	300	27	introduction	introduction	NOUN
bracis-19059	300	28	to	to	ADP
bracis-19059	300	29	data	datum	NOUN
bracis-19059	300	30	mining	mining	NOUN
bracis-19059	300	31	.	.	PUNCT
bracis-19059	301	1	pearson	pearson	PROPN
bracis-19059	301	2	education	education	PROPN
bracis-19059	301	3	,	,	PUNCT
bracis-19059	301	4	london	london	PROPN
bracis-19059	301	5	(	(	PUNCT
bracis-19059	301	6	2016	2016	NUM
bracis-19059	301	7	)	)	PUNCT
bracis-19059	301	8	google	google	PROPN
bracis-19059	301	9	scholar	scholar	NOUN
bracis-19059	301	10	  	  	SPACE
bracis-19059	301	11	verli	verli	NOUN
bracis-19059	301	12	,	,	PUNCT
bracis-19059	301	13	h.	h.	NOUN
bracis-19059	301	14	:	:	PUNCT
bracis-19059	301	15	bioinformática	bioinformática	PROPN
bracis-19059	301	16	:	:	PUNCT
bracis-19059	301	17	da	da	PROPN
bracis-19059	301	18	biologia	biologia	X
bracis-19059	301	19	à	à	X
bracis-19059	301	20	flexibilidade	flexibilidade	NOUN
bracis-19059	301	21	molecular	molecular	ADJ
bracis-19059	301	22	.	.	PUNCT
bracis-19059	302	1	sociedade	sociedade	PROPN
bracis-19059	302	2	brasileira	brasileira	PROPN
bracis-19059	302	3	de	de	PROPN
bracis-19059	302	4	bioquímica	bioquímica	PROPN
bracis-19059	302	5	e	e	PROPN
bracis-19059	302	6	biologia	biologia	PROPN
bracis-19059	302	7	molecular	molecular	ADJ
bracis-19059	302	8	(	(	PUNCT
bracis-19059	302	9	2014	2014	NUM
bracis-19059	302	10	)	)	PUNCT
bracis-19059	302	11	google	google	PROPN
bracis-19059	302	12	scholar	scholar	NOUN
bracis-19059	302	13	  	  	SPACE
bracis-19059	302	14	witten	witten	PROPN
bracis-19059	302	15	,	,	PUNCT
bracis-19059	302	16	i.h	i.h	PROPN
bracis-19059	302	17	.	.	PROPN
bracis-19059	302	18	,	,	PUNCT
bracis-19059	302	19	frank	frank	PROPN
bracis-19059	302	20	,	,	PUNCT
bracis-19059	302	21	e.	e.	PROPN
bracis-19059	302	22	,	,	PUNCT
bracis-19059	302	23	hall	hall	PROPN
bracis-19059	302	24	,	,	PUNCT
bracis-19059	302	25	m.a	m.a	PROPN
bracis-19059	302	26	.	.	PROPN
bracis-19059	302	27	:	:	PUNCT
bracis-19059	303	1	data	datum	NOUN
bracis-19059	303	2	mining	mining	NOUN
bracis-19059	303	3	practical	practical	ADJ
bracis-19059	303	4	machine	machine	NOUN
bracis-19059	303	5	learning	learning	NOUN
bracis-19059	303	6	tools	tool	NOUN
bracis-19059	303	7	and	and	CCONJ
bracis-19059	303	8	techniques	technique	NOUN
bracis-19059	303	9	third	third	PROPN
bracis-19059	303	10	edition	edition	PROPN
bracis-19059	303	11	.	.	PUNCT
bracis-19059	304	1	morgan	morgan	PROPN
bracis-19059	304	2	kaufmann	kaufmann	PROPN
bracis-19059	304	3	,	,	PUNCT
bracis-19059	304	4	burlington	burlington	PROPN
bracis-19059	304	5	(	(	PUNCT
bracis-19059	304	6	2016	2016	NUM
bracis-19059	304	7	)	)	PUNCT
bracis-19059	304	8	google	google	PROPN
bracis-19059	304	9	scholar	scholar	NOUN
bracis-19059	304	10	  	  	SPACE
bracis-19059	304	11	worth	worth	NOUN
bracis-19059	304	12	,	,	PUNCT
bracis-19059	304	13	c.l	c.l	PROPN
bracis-19059	304	14	.	.	PROPN
bracis-19059	304	15	,	,	PUNCT
bracis-19059	304	16	preissner	preissner	PROPN
bracis-19059	304	17	,	,	PUNCT
bracis-19059	304	18	r.	r.	PROPN
bracis-19059	304	19	,	,	PUNCT
bracis-19059	304	20	blundell	blundell	PROPN
bracis-19059	304	21	,	,	PUNCT
bracis-19059	304	22	t.l	t.l	PROPN
bracis-19059	304	23	.	.	PUNCT
bracis-19059	304	24	:	:	PUNCT
bracis-19059	305	1	sdm	sdm	PROPN
bracis-19059	305	2	-	-	PUNCT
bracis-19059	305	3	a	a	DET
bracis-19059	305	4	server	server	NOUN
bracis-19059	305	5	for	for	ADP
bracis-19059	305	6	predicting	predict	VERB
bracis-19059	305	7	effects	effect	NOUN
bracis-19059	305	8	of	of	ADP
bracis-19059	305	9	mutations	mutation	NOUN
bracis-19059	305	10	on	on	ADP
bracis-19059	305	11	protein	protein	NOUN
bracis-19059	305	12	stability	stability	NOUN
bracis-19059	305	13	and	and	CCONJ
bracis-19059	305	14	malfunction	malfunction	NOUN
bracis-19059	305	15	.	.	PUNCT
bracis-19059	306	1	nucl	nucl	PROPN
bracis-19059	306	2	.	.	PUNCT
bracis-19059	307	1	acids	acid	NOUN
bracis-19059	307	2	res	re	NOUN
bracis-19059	307	3	.	.	PUNCT
bracis-19059	308	1	39(suppl_2	39(suppl_2	NUM
bracis-19059	308	2	)	)	PUNCT
bracis-19059	308	3	,	,	PUNCT
bracis-19059	308	4	w215	w215	PROPN
bracis-19059	308	5	–	–	PUNCT
bracis-19059	308	6	w222	w222	PROPN
bracis-19059	308	7	(	(	PUNCT
bracis-19059	308	8	2011	2011	NUM
bracis-19059	308	9	)	)	PUNCT
bracis-19059	308	10	google	google	PROPN
bracis-19059	308	11	scholar	scholar	NOUN
bracis-19059	308	12	  	  	SPACE
bracis-19059	308	13	yang	yang	PROPN
bracis-19059	308	14	,	,	PUNCT
bracis-19059	308	15	p.	p.	PROPN
bracis-19059	308	16	,	,	PUNCT
bracis-19059	308	17	yang	yang	PROPN
bracis-19059	308	18	,	,	PUNCT
bracis-19059	308	19	y.h	y.h	PROPN
bracis-19059	308	20	.	.	PROPN
bracis-19059	308	21	,	,	PUNCT
bracis-19059	308	22	zhou	zhou	PROPN
bracis-19059	308	23	,	,	PUNCT
bracis-19059	308	24	b.b	b.b	PROPN
bracis-19059	308	25	.	.	PROPN
bracis-19059	308	26	,	,	PUNCT
bracis-19059	308	27	zomaya	zomaya	PROPN
bracis-19059	308	28	,	,	PUNCT
bracis-19059	308	29	a.y	a.y	PROPN
bracis-19059	308	30	.	.	PROPN
bracis-19059	308	31	:	:	PUNCT
bracis-19059	309	1	a	a	DET
bracis-19059	309	2	review	review	NOUN
bracis-19059	309	3	of	of	ADP
bracis-19059	309	4	ensemble	ensemble	ADJ
bracis-19059	309	5	methods	method	NOUN
bracis-19059	309	6	in	in	ADP
bracis-19059	309	7	bioinformatics	bioinformatics	NOUN
bracis-19059	309	8	.	.	PUNCT
bracis-19059	310	1	current	current	ADJ
bracis-19059	310	2	bioinform	bioinform	NOUN
bracis-19059	310	3	.	.	PUNCT
bracis-19059	311	1	5(4	5(4	X
bracis-19059	311	2	)	)	PUNCT
bracis-19059	311	3	,	,	PUNCT
bracis-19059	311	4	296–308	296–308	NUM
bracis-19059	311	5	(	(	PUNCT
bracis-19059	311	6	2010	2010	NUM
bracis-19059	311	7	)	)	PUNCT
bracis-19059	311	8	google	google	PROPN
bracis-19059	311	9	scholar	scholar	NOUN
bracis-19059	311	10	  	  	SPACE
bracis-19059	311	11	yang	yang	PROPN
bracis-19059	311	12	,	,	PUNCT
bracis-19059	311	13	y.	y.	NOUN
bracis-19059	311	14	:	:	PUNCT
bracis-19059	311	15	temporal	temporal	ADJ
bracis-19059	311	16	data	datum	NOUN
bracis-19059	311	17	mining	mining	NOUN
bracis-19059	311	18	via	via	ADP
bracis-19059	311	19	unsupervised	unsupervised	ADJ
bracis-19059	311	20	ensemble	ensemble	ADJ
bracis-19059	311	21	learning	learning	NOUN
bracis-19059	311	22	.	.	PUNCT
bracis-19059	312	1	elsevier	elsevier	PROPN
bracis-19059	312	2	,	,	PUNCT
bracis-19059	312	3	amsterdam	amsterdam	PROPN
bracis-19059	312	4	(	(	PUNCT
bracis-19059	312	5	2016	2016	NUM
bracis-19059	312	6	)	)	PUNCT
bracis-19059	312	7	google	google	PROPN
bracis-19059	312	8	scholar	scholar	NOUN
bracis-19059	312	9	  	  	SPACE
bracis-19059	312	10	yin	yin	PROPN
bracis-19059	312	11	,	,	PUNCT
bracis-19059	312	12	s.	s.	PROPN
bracis-19059	312	13	,	,	PUNCT
bracis-19059	312	14	ding	ding	PROPN
bracis-19059	312	15	,	,	PUNCT
bracis-19059	312	16	f.	f.	PROPN
bracis-19059	312	17	,	,	PUNCT
bracis-19059	312	18	dokholyan	dokholyan	PROPN
bracis-19059	312	19	,	,	PUNCT
bracis-19059	312	20	n.v	n.v	PROPN
bracis-19059	312	21	.	.	PUNCT
bracis-19059	312	22	:	:	PUNCT
bracis-19059	313	1	eris	eris	PROPN
bracis-19059	313	2	:	:	PUNCT
bracis-19059	313	3	an	an	DET
bracis-19059	313	4	automated	automated	ADJ
bracis-19059	313	5	estimator	estimator	NOUN
bracis-19059	313	6	of	of	ADP
bracis-19059	313	7	protein	protein	NOUN
bracis-19059	313	8	stability	stability	NOUN
bracis-19059	313	9	.	.	PUNCT
bracis-19059	314	1	nat	nat	NOUN
bracis-19059	314	2	.	.	PUNCT
bracis-19059	315	1	meth	meth	NOUN
bracis-19059	315	2	.	.	PUNCT
bracis-19059	316	1	4(6	4(6	NUM
bracis-19059	316	2	)	)	PUNCT
bracis-19059	316	3	,	,	PUNCT
bracis-19059	316	4	466–467	466–467	NUM
bracis-19059	316	5	(	(	PUNCT
bracis-19059	316	6	2007	2007	NUM
bracis-19059	316	7	)	)	PUNCT
bracis-19059	316	8	.	.	PUNCT
bracis-19059	317	1	https://doi.org/10.1038/nmeth0607-466	https://doi.org/10.1038/nmeth0607-466	PROPN
bracis-19059	317	2	article	article	NOUN
bracis-19059	317	3	  	  	SPACE
bracis-19059	317	4	google	google	PROPN
bracis-19059	317	5	scholar	scholar	PROPN
bracis-19059	317	6	  	  	SPACE
bracis-19059	317	7	zhang	zhang	PROPN
bracis-19059	317	8	,	,	PUNCT
bracis-19059	317	9	z.	z.	PROPN
bracis-19059	317	10	,	,	PUNCT
bracis-19059	317	11	miteva	miteva	PROPN
bracis-19059	317	12	,	,	PUNCT
bracis-19059	317	13	m.a	m.a	PROPN
bracis-19059	317	14	.	.	PROPN
bracis-19059	317	15	,	,	PUNCT
bracis-19059	317	16	wang	wang	PROPN
bracis-19059	317	17	,	,	PUNCT
bracis-19059	317	18	l.	l.	PROPN
bracis-19059	317	19	,	,	PUNCT
bracis-19059	317	20	alexov	alexov	PROPN
bracis-19059	317	21	,	,	PUNCT
bracis-19059	317	22	e.	e.	PROPN
bracis-19059	317	23	:	:	PUNCT
bracis-19059	317	24	analyzing	analyze	VERB
bracis-19059	317	25	effects	effect	NOUN
bracis-19059	317	26	of	of	ADP
bracis-19059	317	27	naturally	naturally	ADV
bracis-19059	317	28	occurring	occur	VERB
bracis-19059	317	29	missense	missense	NOUN
bracis-19059	317	30	mutations	mutation	NOUN
bracis-19059	317	31	.	.	PUNCT
bracis-19059	318	1	comput	comput	NOUN
bracis-19059	318	2	.	.	PUNCT
bracis-19059	319	1	math	math	NOUN
bracis-19059	319	2	.	.	PUNCT
bracis-19059	320	1	meth	meth	NOUN
bracis-19059	320	2	.	.	PUNCT
bracis-19059	321	1	med	med	PROPN
bracis-19059	321	2	.	.	PROPN
bracis-19059	321	3	2012	2012	NUM
bracis-19059	321	4	,	,	PUNCT
bracis-19059	321	5	1–15	1–15	PROPN
bracis-19059	321	6	(	(	PUNCT
bracis-19059	321	7	2012	2012	NUM
bracis-19059	321	8	)	)	PUNCT
bracis-19059	321	9	.	.	PUNCT
bracis-19059	322	1	https://doi.org/10.1155/2012/805827	https://doi.org/10.1155/2012/805827	PROPN
bracis-19059	322	2	article	article	PROPN
bracis-19059	322	3	  	  	SPACE
bracis-19059	322	4	math	math	NOUN
bracis-19059	322	5	  	  	SPACE
bracis-19059	322	6	google	google	PROPN
bracis-19059	322	7	scholar	scholar	NOUN
bracis-19059	322	8	  	  	SPACE
bracis-19059	322	9	zhou	zhou	PROPN
bracis-19059	322	10	,	,	PUNCT
bracis-19059	322	11	h.	h.	PROPN
bracis-19059	322	12	,	,	PUNCT
bracis-19059	322	13	zhou	zhou	PROPN
bracis-19059	322	14	,	,	PUNCT
bracis-19059	322	15	y.	y.	NOUN
bracis-19059	322	16	:	:	PUNCT
bracis-19059	322	17	distance	distance	NOUN
bracis-19059	322	18	-	-	PUNCT
bracis-19059	322	19	scaled	scale	VERB
bracis-19059	322	20	,	,	PUNCT
bracis-19059	322	21	finite	finite	ADJ
bracis-19059	322	22	ideal	ideal	ADJ
bracis-19059	322	23	-	-	PUNCT
bracis-19059	322	24	gas	gas	NOUN
bracis-19059	322	25	reference	reference	NOUN
bracis-19059	322	26	state	state	NOUN
bracis-19059	322	27	improves	improve	VERB
bracis-19059	322	28	structure	structure	NOUN
bracis-19059	322	29	-	-	PUNCT
bracis-19059	322	30	derived	derive	VERB
bracis-19059	322	31	potentials	potential	NOUN
bracis-19059	322	32	of	of	ADP
bracis-19059	322	33	mean	mean	ADJ
bracis-19059	322	34	force	force	NOUN
bracis-19059	322	35	for	for	ADP
bracis-19059	322	36	structure	structure	NOUN
bracis-19059	322	37	selection	selection	NOUN
bracis-19059	322	38	and	and	CCONJ
bracis-19059	322	39	stability	stability	NOUN
bracis-19059	322	40	prediction	prediction	NOUN
bracis-19059	322	41	.	.	PUNCT
bracis-19059	323	1	prot	prot	NOUN
bracis-19059	323	2	.	.	PUNCT
bracis-19059	324	1	sci	sci	PROPN
bracis-19059	324	2	.	.	PUNCT
bracis-19059	324	3	11(11	11(11	NUM
bracis-19059	324	4	)	)	PUNCT
bracis-19059	324	5	,	,	PUNCT
bracis-19059	324	6	2714–2726	2714–2726	NUM
bracis-19059	324	7	(	(	PUNCT
bracis-19059	324	8	2009	2009	NUM
bracis-19059	324	9	)	)	PUNCT
bracis-19059	324	10	.	.	PUNCT
bracis-19059	325	1	https://doi.org/10.1110/ps.0217002	https://doi.org/10.1110/ps.0217002	PROPN
bracis-19059	325	2	article	article	NOUN
bracis-19059	325	3	  	  	SPACE
bracis-19059	325	4	google	google	PROPN
bracis-19059	325	5	scholar	scholar	NOUN
bracis-19059	325	6	  	  	SPACE
bracis-19059	325	7	zhou	zhou	PROPN
bracis-19059	325	8	,	,	PUNCT
bracis-19059	325	9	z.h	z.h	PROPN
bracis-19059	325	10	.	.	PROPN
bracis-19059	325	11	:	:	PUNCT
bracis-19059	325	12	ensemble	ensemble	ADJ
bracis-19059	325	13	methods	method	NOUN
bracis-19059	325	14	:	:	PUNCT
bracis-19059	325	15	foundations	foundation	NOUN
bracis-19059	325	16	and	and	CCONJ
bracis-19059	325	17	algorithms	algorithm	NOUN
bracis-19059	325	18	.	.	PUNCT
bracis-19059	326	1	chapman	chapman	NOUN
bracis-19059	326	2	and	and	CCONJ
bracis-19059	326	3	hall	hall	PROPN
bracis-19059	326	4	/	/	SYM
bracis-19059	326	5	crc	crc	PROPN
bracis-19059	326	6	,	,	PUNCT
bracis-19059	326	7	boca	boca	PROPN
bracis-19059	326	8	raton	raton	PROPN
bracis-19059	326	9	(	(	PUNCT
bracis-19059	326	10	2019	2019	NUM
bracis-19059	326	11	)	)	PUNCT
bracis-19059	326	12	google	google	NOUN
bracis-19059	326	13	scholar	scholar	NOUN
bracis-19059	326	14	  	  	SPACE
bracis-19059	326	15	download	download	NOUN
bracis-19059	326	16	references	reference	NOUN
bracis-19059	326	17	author	author	NOUN
bracis-19059	326	18	information	information	NOUN
bracis-19059	326	19	authors	author	NOUN
bracis-19059	326	20	and	and	CCONJ
bracis-19059	326	21	affiliations	affiliation	NOUN
bracis-19059	326	22	computational	computational	ADJ
bracis-19059	326	23	biology	biology	NOUN
bracis-19059	326	24	laboratory	laboratory	PROPN
bracis-19059	326	25	combi	combi	PROPN
bracis-19059	326	26	-	-	PUNCT
bracis-19059	326	27	lab	lab	PROPN
bracis-19059	326	28	,	,	PUNCT
bracis-19059	326	29	centro	centro	X
bracis-19059	326	30	de	de	PROPN
bracis-19059	326	31	ciências	ciências	PROPN
bracis-19059	326	32	computacionais	computacionais	PROPN
bracis-19059	326	33	,	,	PUNCT
bracis-19059	326	34	universidade	universidade	PROPN
bracis-19059	326	35	federal	federal	PROPN
bracis-19059	326	36	do	do	AUX
bracis-19059	326	37	rio	rio	PROPN
bracis-19059	326	38	grande	grande	PROPN
bracis-19059	326	39	furg	furg	PROPN
bracis-19059	326	40	,	,	PUNCT
bracis-19059	326	41	av	av	PROPN
bracis-19059	326	42	.	.	PUNCT
bracis-19059	326	43	itália	itália	PROPN
bracis-19059	326	44	,	,	PUNCT
bracis-19059	326	45	km	km	NOUN
bracis-19059	326	46	8	8	NUM
bracis-19059	326	47	,	,	PUNCT
bracis-19059	326	48	rio	rio	NOUN
bracis-19059	326	49	grande	grande	PROPN
bracis-19059	326	50	,	,	PUNCT
bracis-19059	326	51	rs	rs	PROPN
bracis-19059	326	52	,	,	PUNCT
bracis-19059	326	53	brazil	brazil	PROPN
bracis-19059	326	54	eduardo	eduardo	PROPN
bracis-19059	326	55	kenji	kenji	PROPN
bracis-19059	326	56	hasegawa	hasegawa	PROPN
bracis-19059	326	57	de	de	PROPN
bracis-19059	326	58	freitas	freitas	PROPN
bracis-19059	326	59	,	,	PUNCT
bracis-19059	326	60	 	 	SPACE
bracis-19059	326	61	alex	alex	PROPN
bracis-19059	326	62	dias	dias	PROPN
bracis-19059	326	63	camargo	camargo	PROPN
bracis-19059	326	64	,	,	PUNCT
bracis-19059	326	65	 	 	SPACE
bracis-19059	326	66	maurício	maurício	NOUN
bracis-19059	326	67	balboni	balboni	NOUN
bracis-19059	326	68	,	,	PUNCT
bracis-19059	326	69	 	 	SPACE
bracis-19059	326	70	adriano	adriano	PROPN
bracis-19059	326	71	v.	v.	ADP
bracis-19059	326	72	werhli	werhli	PROPN
bracis-19059	326	73	 	 	SPACE
bracis-19059	326	74	&	&	CCONJ
bracis-19059	326	75	 	 	SPACE
bracis-19059	326	76	karina	karina	PROPN
bracis-19059	326	77	dos	dos	PROPN
bracis-19059	326	78	santos	santos	PROPN
bracis-19059	326	79	machado	machado	PROPN
bracis-19059	326	80	authors	authors	PROPN
bracis-19059	326	81	eduardo	eduardo	PROPN
bracis-19059	326	82	kenji	kenji	PROPN
bracis-19059	326	83	hasegawa	hasegawa	PROPN
bracis-19059	326	84	de	de	PROPN
bracis-19059	326	85	freitasview	freitasview	PROPN
bracis-19059	326	86	author	author	NOUN
bracis-19059	326	87	publications	publication	NOUN
bracis-19059	326	88	search	search	NOUN
bracis-19059	326	89	author	author	NOUN
bracis-19059	326	90	on	on	ADP
bracis-19059	326	91	:	:	PUNCT
bracis-19059	326	92	pubmed	pubmed	PROPN
bracis-19059	326	93	 	 	SPACE
bracis-19059	326	94	google	google	PROPN
bracis-19059	326	95	scholar	scholar	PROPN
bracis-19059	326	96	alex	alex	PROPN
bracis-19059	326	97	dias	dias	PROPN
bracis-19059	326	98	camargoview	camargoview	PROPN
bracis-19059	326	99	author	author	NOUN
bracis-19059	326	100	publications	publication	NOUN
bracis-19059	326	101	search	search	NOUN
bracis-19059	326	102	author	author	NOUN
bracis-19059	326	103	on	on	ADP
bracis-19059	326	104	:	:	PUNCT
bracis-19059	326	105	pubmed	pubmed	PROPN
bracis-19059	326	106	 	 	SPACE
bracis-19059	326	107	google	google	PROPN
bracis-19059	326	108	scholar	scholar	NOUN
bracis-19059	326	109	maurício	maurício	NOUN
bracis-19059	326	110	balboniview	balboniview	NOUN
bracis-19059	326	111	author	author	NOUN
bracis-19059	326	112	publications	publication	NOUN
bracis-19059	326	113	search	search	NOUN
bracis-19059	326	114	author	author	NOUN
bracis-19059	326	115	on	on	ADP
bracis-19059	326	116	:	:	PUNCT
bracis-19059	326	117	pubmed	pubmed	PROPN
bracis-19059	326	118	 	 	SPACE
bracis-19059	326	119	google	google	PROPN
bracis-19059	326	120	scholar	scholar	NOUN
bracis-19059	326	121	adriano	adriano	PROPN
bracis-19059	326	122	v.	v.	ADP
bracis-19059	326	123	werhliview	werhliview	ADJ
bracis-19059	326	124	author	author	NOUN
bracis-19059	326	125	publications	publication	NOUN
bracis-19059	326	126	search	search	NOUN
bracis-19059	326	127	author	author	NOUN
bracis-19059	326	128	on	on	ADP
bracis-19059	326	129	:	:	PUNCT
bracis-19059	326	130	pubmed	pubmed	PROPN
bracis-19059	326	131	 	 	SPACE
bracis-19059	326	132	google	google	PROPN
bracis-19059	326	133	scholar	scholar	PROPN
bracis-19059	326	134	karina	karina	PROPN
bracis-19059	326	135	dos	dos	PROPN
bracis-19059	326	136	santos	santos	PROPN
bracis-19059	326	137	machadoview	machadoview	PROPN
bracis-19059	326	138	author	author	NOUN
bracis-19059	326	139	publications	publication	NOUN
bracis-19059	326	140	search	search	NOUN
bracis-19059	326	141	author	author	NOUN
bracis-19059	326	142	on	on	ADP
bracis-19059	326	143	:	:	PUNCT
bracis-19059	326	144	pubmed	pubmed	PROPN
bracis-19059	326	145	 	 	SPACE
bracis-19059	326	146	google	google	PROPN
bracis-19059	326	147	scholar	scholar	NOUN
bracis-19059	326	148	corresponding	correspond	VERB
bracis-19059	326	149	author	author	NOUN
bracis-19059	326	150	correspondence	correspondence	NOUN
bracis-19059	326	151	to	to	ADP
bracis-19059	326	152	karina	karina	PROPN
bracis-19059	326	153	dos	dos	PROPN
bracis-19059	326	154	santos	santos	PROPN
bracis-19059	326	155	machado	machado	PROPN
bracis-19059	326	156	.	.	PUNCT
bracis-19059	327	1	editor	editor	NOUN
bracis-19059	327	2	information	information	NOUN
bracis-19059	327	3	editors	editor	NOUN
bracis-19059	327	4	and	and	CCONJ
bracis-19059	327	5	affiliations	affiliation	NOUN
bracis-19059	327	6	universidade	universidade	PROPN
bracis-19059	327	7	federal	federal	PROPN
bracis-19059	327	8	de	de	X
bracis-19059	327	9	sergipe	sergipe	PROPN
bracis-19059	327	10	,	,	PUNCT
bracis-19059	327	11	são	são	NOUN
bracis-19059	327	12	cristóvão	cristóvão	PROPN
bracis-19059	327	13	,	,	PUNCT
bracis-19059	327	14	brazil	brazil	PROPN
bracis-19059	327	15	andré	andré	PROPN
bracis-19059	327	16	britto	britto	PROPN
bracis-19059	327	17	universidade	universidade	PROPN
bracis-19059	327	18	de	de	PROPN
bracis-19059	327	19	são	são	PROPN
bracis-19059	327	20	paulo	paulo	PROPN
bracis-19059	327	21	,	,	PUNCT
bracis-19059	327	22	são	são	PROPN
bracis-19059	327	23	paulo	paulo	PROPN
bracis-19059	327	24	,	,	PUNCT
bracis-19059	327	25	brazil	brazil	PROPN
bracis-19059	327	26	karina	karina	PROPN
bracis-19059	327	27	valdivia	valdivia	PROPN
bracis-19059	327	28	delgado	delgado	VERB
bracis-19059	327	29	rights	right	NOUN
bracis-19059	327	30	and	and	CCONJ
bracis-19059	327	31	permissions	permission	NOUN
bracis-19059	327	32	reprints	reprint	NOUN
bracis-19059	327	33	and	and	CCONJ
bracis-19059	327	34	permissions	permission	VERB
bracis-19059	327	35	copyright	copyright	NOUN
bracis-19059	327	36	information	information	NOUN
bracis-19059	327	37	©	©	PROPN
bracis-19059	327	38	2021	2021	NUM
bracis-19059	327	39	springer	springer	NOUN
bracis-19059	327	40	nature	nature	NOUN
bracis-19059	327	41	switzerland	switzerland	PROPN
bracis-19059	327	42	ag	ag	PROPN
bracis-19059	327	43	about	about	ADP
bracis-19059	327	44	this	this	DET
bracis-19059	327	45	paper	paper	NOUN
bracis-19059	327	46	cite	cite	VERB
bracis-19059	327	47	this	this	DET
bracis-19059	327	48	paper	paper	NOUN
bracis-19059	327	49	de	de	ADP
bracis-19059	327	50	freitas	freitas	PROPN
bracis-19059	327	51	,	,	PUNCT
bracis-19059	327	52	e.k.h	e.k.h	PROPN
bracis-19059	327	53	.	.	PROPN
bracis-19059	327	54	,	,	PUNCT
bracis-19059	327	55	camargo	camargo	PROPN
bracis-19059	327	56	,	,	PUNCT
bracis-19059	327	57	a.d	a.d	PROPN
bracis-19059	327	58	.	.	PROPN
bracis-19059	327	59	,	,	PUNCT
bracis-19059	327	60	balboni	balboni	PROPN
bracis-19059	327	61	,	,	PUNCT
bracis-19059	327	62	m.	m.	NOUN
bracis-19059	327	63	,	,	PUNCT
bracis-19059	327	64	werhli	werhli	PROPN
bracis-19059	327	65	,	,	PUNCT
bracis-19059	327	66	a.v	a.v	PROPN
bracis-19059	327	67	.	.	PROPN
bracis-19059	327	68	,	,	PUNCT
bracis-19059	327	69	dos	do	VERB
bracis-19059	327	70	santos	santos	PROPN
bracis-19059	327	71	machado	machado	PROPN
bracis-19059	327	72	,	,	PUNCT
bracis-19059	327	73	k.	k.	PROPN
bracis-19059	327	74	(	(	PUNCT
bracis-19059	327	75	2021	2021	NUM
bracis-19059	327	76	)	)	PUNCT
bracis-19059	327	77	.	.	PUNCT
bracis-19059	328	1	ensemble	ensemble	ADJ
bracis-19059	328	2	of	of	ADP
bracis-19059	328	3	protein	protein	NOUN
bracis-19059	328	4	stability	stability	NOUN
bracis-19059	328	5	upon	upon	SCONJ
bracis-19059	328	6	point	point	NOUN
bracis-19059	328	7	mutation	mutation	NOUN
bracis-19059	328	8	predictors	predictor	NOUN
bracis-19059	328	9	.	.	PUNCT
bracis-19059	329	1	in	in	ADP
bracis-19059	329	2	:	:	PUNCT
bracis-19059	329	3	britto	britto	PROPN
bracis-19059	329	4	,	,	PUNCT
bracis-19059	329	5	a.	a.	PROPN
bracis-19059	329	6	,	,	PUNCT
bracis-19059	329	7	valdivia	valdivia	PROPN
bracis-19059	329	8	delgado	delgado	PROPN
bracis-19059	329	9	,	,	PUNCT
bracis-19059	329	10	k.	k.	PROPN
bracis-19059	329	11	(	(	PUNCT
bracis-19059	329	12	eds	eds	PROPN
bracis-19059	329	13	)	)	PUNCT
bracis-19059	329	14	intelligent	intelligent	ADJ
bracis-19059	329	15	systems	system	NOUN
bracis-19059	329	16	.	.	PUNCT
bracis-19059	330	1	bracis	bracis	PROPN
bracis-19059	330	2	2021	2021	NUM
bracis-19059	330	3	.	.	PUNCT
bracis-19059	331	1	lecture	lecture	NOUN
bracis-19059	331	2	notes	note	NOUN
bracis-19059	331	3	in	in	ADP
bracis-19059	331	4	computer	computer	NOUN
bracis-19059	331	5	science	science	NOUN
bracis-19059	331	6	(	(	PUNCT
bracis-19059	331	7	)	)	PUNCT
bracis-19059	331	8	,	,	PUNCT
bracis-19059	331	9	vol	vol	NOUN
bracis-19059	331	10	13074	13074	NUM
bracis-19059	331	11	.	.	PUNCT
bracis-19059	332	1	springer	springer	NOUN
bracis-19059	332	2	,	,	PUNCT
bracis-19059	332	3	cham	cham	PROPN
bracis-19059	332	4	.	.	PUNCT
bracis-19059	333	1	https://doi.org/10.1007/978-3-030-91699-2_6	https://doi.org/10.1007/978-3-030-91699-2_6	PROPN
bracis-19059	333	2	download	download	PROPN
bracis-19059	333	3	citation	citation	PROPN
bracis-19059	333	4	.ris	.ris	PUNCT
bracis-19059	333	5	.enw	.enw	PROPN
bracis-19059	333	6	.bib	.bib	PUNCT
bracis-19059	334	1	doi	doi	PROPN
bracis-19059	334	2	:	:	PUNCT
bracis-19059	334	3	https://doi.org/10.1007/978-3-030-91699-2_6	https://doi.org/10.1007/978-3-030-91699-2_6	X
bracis-19059	334	4	published	publish	VERB
bracis-19059	334	5	:	:	PUNCT
bracis-19059	334	6	28	28	NUM
bracis-19059	334	7	november	november	PROPN
bracis-19059	334	8	2021	2021	NUM
bracis-19059	334	9	publisher	publisher	NOUN
bracis-19059	334	10	name	name	NOUN
bracis-19059	334	11	:	:	PUNCT
bracis-19059	334	12	springer	springer	NOUN
bracis-19059	334	13	,	,	PUNCT
bracis-19059	334	14	cham	cham	PROPN
bracis-19059	334	15	print	print	PROPN
bracis-19059	334	16	isbn	isbn	PROPN
bracis-19059	334	17	:	:	PUNCT
bracis-19059	334	18	978	978	NUM
bracis-19059	334	19	-	-	SYM
bracis-19059	334	20	3	3	NUM
bracis-19059	334	21	-	-	PUNCT
bracis-19059	334	22	030	030	NUM
bracis-19059	334	23	-	-	PUNCT
bracis-19059	334	24	91698	91698	NUM
bracis-19059	334	25	-	-	SYM
bracis-19059	334	26	5	5	NUM
bracis-19059	334	27	online	online	ADJ
bracis-19059	334	28	isbn	isbn	NOUN
bracis-19059	334	29	:	:	PUNCT
bracis-19059	334	30	978	978	NUM
bracis-19059	334	31	-	-	SYM
bracis-19059	334	32	3	3	NUM
bracis-19059	334	33	-	-	PUNCT
bracis-19059	334	34	030	030	NUM
bracis-19059	334	35	-	-	PUNCT
bracis-19059	334	36	91699	91699	NUM
bracis-19059	334	37	-	-	SYM
bracis-19059	334	38	2	2	NUM
bracis-19059	334	39	ebook	ebook	NOUN
bracis-19059	334	40	packages	package	NOUN
bracis-19059	334	41	:	:	PUNCT
bracis-19059	334	42	computer	computer	NOUN
bracis-19059	334	43	sciencecomputer	sciencecomputer	NOUN
bracis-19059	334	44	science	science	NOUN
bracis-19059	334	45	(	(	PUNCT
bracis-19059	334	46	r0	r0	NOUN
bracis-19059	334	47	)	)	PUNCT
bracis-19059	334	48	share	share	VERB
bracis-19059	334	49	this	this	DET
bracis-19059	334	50	paper	paper	NOUN
bracis-19059	334	51	anyone	anyone	PRON
bracis-19059	335	1	you	you	PRON
bracis-19059	335	2	share	share	VERB
bracis-19059	335	3	the	the	DET
bracis-19059	335	4	following	follow	VERB
bracis-19059	335	5	link	link	NOUN
bracis-19059	335	6	with	with	ADP
bracis-19059	335	7	will	will	AUX
bracis-19059	335	8	be	be	AUX
bracis-19059	335	9	able	able	ADJ
bracis-19059	335	10	to	to	PART
bracis-19059	335	11	read	read	VERB
bracis-19059	335	12	this	this	DET
bracis-19059	335	13	content	content	NOUN
bracis-19059	335	14	:	:	PUNCT
bracis-19059	335	15	get	get	VERB
bracis-19059	335	16	shareable	shareable	ADJ
bracis-19059	335	17	linksorry	linksorry	NOUN
bracis-19059	335	18	,	,	PUNCT
bracis-19059	335	19	a	a	DET
bracis-19059	335	20	shareable	shareable	ADJ
bracis-19059	335	21	link	link	NOUN
bracis-19059	335	22	is	be	AUX
bracis-19059	335	23	not	not	PART
bracis-19059	335	24	currently	currently	ADV
bracis-19059	335	25	available	available	ADJ
bracis-19059	335	26	for	for	ADP
bracis-19059	335	27	this	this	DET
bracis-19059	335	28	article	article	NOUN
bracis-19059	335	29	.	.	PUNCT
bracis-19059	336	1	copy	copy	VERB
bracis-19059	336	2	shareable	shareable	ADJ
bracis-19059	336	3	link	link	NOUN
bracis-19059	336	4	to	to	PART
bracis-19059	336	5	clipboard	clipboard	NOUN
bracis-19059	336	6	provided	provide	VERB
bracis-19059	336	7	by	by	ADP
bracis-19059	336	8	the	the	DET
bracis-19059	336	9	springer	springer	NOUN
bracis-19059	336	10	nature	nature	PROPN
bracis-19059	336	11	sharedit	sharedit	PROPN
bracis-19059	336	12	content	content	NOUN
bracis-19059	336	13	-	-	PUNCT
bracis-19059	336	14	sharing	share	VERB
bracis-19059	336	15	initiative	initiative	NOUN
bracis-19059	336	16	keywords	keyword	NOUN
bracis-19059	336	17	ensemble	ensemble	ADJ
bracis-19059	336	18	learning	learn	VERB
bracis-19059	336	19	bioinformatics	bioinformatics	NOUN
bracis-19059	336	20	protein	protein	NOUN
bracis-19059	336	21	stability	stability	NOUN
bracis-19059	336	22	point	point	NOUN
bracis-19059	336	23	mutations	mutation	NOUN
bracis-19059	336	24	publish	publish	VERB
bracis-19059	336	25	with	with	ADP
bracis-19059	336	26	us	us	PROPN
bracis-19059	336	27	policies	policy	NOUN
bracis-19059	336	28	and	and	CCONJ
bracis-19059	336	29	ethics	ethic	NOUN
bracis-19059	336	30	search	search	NOUN
bracis-19059	336	31	search	search	NOUN
bracis-19059	336	32	by	by	ADP
bracis-19059	336	33	keyword	keyword	NOUN
bracis-19059	336	34	or	or	CCONJ
bracis-19059	336	35	author	author	NOUN
bracis-19059	336	36	search	search	NOUN
bracis-19059	336	37	navigation	navigation	NOUN
bracis-19059	336	38	find	find	VERB
bracis-19059	336	39	a	a	DET
bracis-19059	336	40	journal	journal	NOUN
bracis-19059	336	41	publish	publish	VERB
bracis-19059	336	42	with	with	ADP
bracis-19059	336	43	us	we	PRON
bracis-19059	336	44	track	track	VERB
bracis-19059	336	45	your	your	PRON
bracis-19059	336	46	research	research	NOUN
bracis-19059	336	47	discover	discover	VERB
bracis-19059	336	48	content	content	NOUN
bracis-19059	336	49	journals	journal	NOUN
bracis-19059	336	50	a	a	DET
bracis-19059	336	51	-	-	PUNCT
bracis-19059	336	52	z	z	NOUN
bracis-19059	336	53	books	book	NOUN
bracis-19059	336	54	a	a	DET
bracis-19059	336	55	-	-	PUNCT
bracis-19059	336	56	z	z	NOUN
bracis-19059	336	57	publish	publish	NOUN
bracis-19059	336	58	with	with	ADP
bracis-19059	336	59	us	us	PROPN
bracis-19059	336	60	journal	journal	PROPN
bracis-19059	336	61	finder	finder	PROPN
bracis-19059	336	62	publish	publish	VERB
bracis-19059	336	63	your	your	PRON
bracis-19059	336	64	research	research	NOUN
bracis-19059	336	65	language	language	NOUN
bracis-19059	336	66	editing	edit	VERB
bracis-19059	336	67	open	open	ADJ
bracis-19059	336	68	access	access	NOUN
bracis-19059	336	69	publishing	publishing	NOUN
bracis-19059	336	70	products	product	NOUN
bracis-19059	336	71	and	and	CCONJ
bracis-19059	336	72	services	service	NOUN
bracis-19059	336	73	our	our	PRON
bracis-19059	336	74	products	product	NOUN
bracis-19059	336	75	librarians	librarian	VERB
bracis-19059	336	76	societies	society	NOUN
bracis-19059	336	77	partners	partner	NOUN
bracis-19059	336	78	and	and	CCONJ
bracis-19059	336	79	advertisers	advertiser	NOUN
bracis-19059	336	80	our	our	PRON
bracis-19059	336	81	brands	brand	NOUN
bracis-19059	336	82	springer	springer	NOUN
bracis-19059	336	83	nature	nature	PROPN
bracis-19059	336	84	portfolio	portfolio	PROPN
bracis-19059	336	85	bmc	bmc	PROPN
bracis-19059	336	86	palgrave	palgrave	PROPN
bracis-19059	336	87	macmillan	macmillan	PROPN
bracis-19059	336	88	apress	apress	PROPN
bracis-19059	336	89	discover	discover	VERB
bracis-19059	336	90	your	your	PRON
bracis-19059	336	91	privacy	privacy	NOUN
bracis-19059	336	92	choices	choice	NOUN
bracis-19059	336	93	/	/	SYM
bracis-19059	336	94	manage	manage	NOUN
bracis-19059	336	95	cookies	cookie	NOUN
bracis-19059	336	96	your	your	PRON
bracis-19059	336	97	us	us	PROPN
bracis-19059	337	1	state	state	NOUN
bracis-19059	337	2	privacy	privacy	NOUN
bracis-19059	337	3	rights	right	NOUN
bracis-19059	337	4	accessibility	accessibility	NOUN
bracis-19059	337	5	statement	statement	NOUN
bracis-19059	337	6	terms	term	NOUN
bracis-19059	337	7	and	and	CCONJ
bracis-19059	337	8	conditions	condition	NOUN
bracis-19059	337	9	privacy	privacy	NOUN
bracis-19059	337	10	policy	policy	NOUN
bracis-19059	337	11	help	help	NOUN
bracis-19059	337	12	and	and	CCONJ
bracis-19059	337	13	support	support	VERB
bracis-19059	337	14	legal	legal	ADJ
bracis-19059	337	15	notice	notice	NOUN
bracis-19059	337	16	cancel	cancel	VERB
bracis-19059	337	17	contracts	contract	NOUN
bracis-19059	337	18	here	here	ADV
bracis-19059	337	19	129.74.145.123	129.74.145.123	NUM
bracis-19059	337	20	hesburgh	hesburgh	PROPN
bracis-19059	337	21	library	library	PROPN
bracis-19059	337	22	er	er	INTJ
bracis-19059	337	23	unit	unit	NOUN
bracis-19059	337	24	(	(	PUNCT
bracis-19059	337	25	3005732405	3005732405	NUM
bracis-19059	337	26	)	)	PUNCT
bracis-19059	337	27	northeast	northeast	ADJ
bracis-19059	337	28	research	research	NOUN
bracis-19059	337	29	libraries	library	NOUN
bracis-19059	337	30	(	(	PUNCT
bracis-19059	337	31	nerl	nerl	PROPN
bracis-19059	337	32	)	)	PUNCT
bracis-19059	337	33	(	(	PUNCT
bracis-19059	337	34	8200828607	8200828607	NUM
bracis-19059	337	35	)	)	PUNCT
bracis-19059	337	36	nerl	nerl	VERB
bracis-19059	337	37	ta	ta	X
bracis-19059	337	38	account	account	NOUN
bracis-19059	337	39	(	(	PUNCT
bracis-19059	337	40	3006206169	3006206169	NUM
bracis-19059	337	41	)	)	PUNCT
bracis-19059	337	42	university	university	NOUN
bracis-19059	337	43	of	of	ADP
bracis-19059	337	44	notre	notre	PROPN
bracis-19059	337	45	dame	dame	PROPN
bracis-19059	337	46	hesburgh	hesburgh	PROPN
bracis-19059	337	47	library	library	NOUN
bracis-19059	337	48	(	(	PUNCT
bracis-19059	337	49	3000184373	3000184373	NUM
bracis-19059	337	50	)	)	PUNCT
bracis-19059	338	1	©	©	ADP
bracis-19059	338	2	2025	2025	NUM
bracis-19059	338	3	springer	springer	NOUN
bracis-19059	338	4	nature	nature	NOUN