id	sid	tid	token	lemma	pos
anesthj-143	1	1	volume	volume	NOUN
anesthj-143	1	2	9no	9no	PROPN
anesthj-143	1	3	.	.	PUNCT
anesthj-143	2	1	1	1	NUM
anesthj-143	2	2	2021	2021	NUM
anesthj-143	2	3	educated	educate	VERB
anesthj-143	2	4	hand	hand	NOUN
anesthj-143	2	5	publishing	publishing	NOUN
anesthj-143	2	6	llc	llc	NOUN
anesthj-143	2	7	“	"	PUNCT
anesthj-143	2	8	the	the	DET
anesthj-143	2	9	science	science	NOUN
anesthj-143	2	10	behind	behind	ADP
anesthj-143	2	11	the	the	DET
anesthj-143	2	12	art	art	NOUN
anesthj-143	2	13	”	"	PUNCT
anesthj-143	2	14	volume	volume	NOUN
anesthj-143	2	15	9	9	NUM
anesthj-143	2	16	no.1	no.1	NUM
anesthj-143	2	17	2021	2021	NUM
anesthj-143	2	18	anesthesia	anesthesia	PROPN
anesthj-143	2	19	ejournal	ejournal	PROPN
anesthj-143	2	20	online	online	PROPN
anesthj-143	2	21	issn	issn	PROPN
anesthj-143	2	22	2333	2333	NUM
anesthj-143	2	23	-	-	SYM
anesthj-143	2	24	2611	2611	NUM
anesthj-143	2	25	page	page	NOUN
anesthj-143	2	26	1	1	NUM
anesthj-143	2	27	anesthetic	anesthetic	NOUN
anesthj-143	2	28	management	management	NOUN
anesthj-143	2	29	of	of	ADP
anesthj-143	2	30	a	a	DET
anesthj-143	2	31	patient	patient	NOUN
anesthj-143	2	32	with	with	ADP
anesthj-143	2	33	hereditary	hereditary	ADJ
anesthj-143	2	34	coproporphyria	coproporphyria	PROPN
anesthj-143	2	35	audrey	audrey	PROPN
anesthj-143	2	36	f.	f.	PROPN
anesthj-143	2	37	fisher	fisher	PROPN
anesthj-143	2	38	,	,	PUNCT
anesthj-143	2	39	bsn	bsn	PROPN
anesthj-143	2	40	,	,	PUNCT
anesthj-143	2	41	rn	rn	PROPN
anesthj-143	2	42	,	,	PUNCT
anesthj-143	2	43	rrna	rrna	PROPN
anesthj-143	2	44	affiliation	affiliation	NOUN
anesthj-143	2	45	:	:	PUNCT
anesthj-143	2	46	texas	texas	PROPN
anesthj-143	2	47	christian	christian	PROPN
anesthj-143	2	48	university	university	PROPN
anesthj-143	2	49	grant	grant	NOUN
anesthj-143	2	50	/	/	SYM
anesthj-143	2	51	financial	financial	ADJ
anesthj-143	2	52	support	support	NOUN
anesthj-143	2	53	:	:	PUNCT
anesthj-143	2	54	none	none	NOUN
anesthj-143	2	55	biographical	biographical	ADJ
anesthj-143	2	56	data	data	PROPN
anesthj-143	2	57	:	:	PUNCT
anesthj-143	2	58	audrey	audrey	PROPN
anesthj-143	2	59	f.	f.	PROPN
anesthj-143	2	60	fisher	fisher	PROPN
anesthj-143	2	61	is	be	AUX
anesthj-143	2	62	a	a	DET
anesthj-143	2	63	registered	registered	ADJ
anesthj-143	2	64	nurse	nurse	NOUN
anesthj-143	2	65	pursuing	pursue	VERB
anesthj-143	2	66	her	her	PRON
anesthj-143	2	67	dnp	dnp	PROPN
anesthj-143	2	68	in	in	ADP
anesthj-143	2	69	nurse	nurse	PROPN
anesthj-143	2	70	anesthesia	anesthesia	PROPN
anesthj-143	2	71	at	at	ADP
anesthj-143	2	72	texas	texas	PROPN
anesthj-143	2	73	christian	christian	PROPN
anesthj-143	2	74	university	university	PROPN
anesthj-143	2	75	in	in	ADP
anesthj-143	2	76	fort	fort	PROPN
anesthj-143	2	77	worth	worth	PROPN
anesthj-143	2	78	,	,	PUNCT
anesthj-143	2	79	texas	texas	PROPN
anesthj-143	2	80	.	.	PUNCT
anesthj-143	3	1	keywords	keyword	NOUN
anesthj-143	3	2	:	:	PUNCT
anesthj-143	3	3	hereditary	hereditary	ADJ
anesthj-143	3	4	coproporphyria	coproporphyria	PROPN
anesthj-143	3	5	,	,	PUNCT
anesthj-143	3	6	porphyria	porphyria	NOUN
anesthj-143	3	7	,	,	PUNCT
anesthj-143	3	8	triggering	trigger	VERB
anesthj-143	3	9	agents	agent	NOUN
anesthj-143	3	10	,	,	PUNCT
anesthj-143	3	11	acute	acute	ADJ
anesthj-143	3	12	attacks	attack	NOUN
anesthj-143	3	13	abstract	abstract	ADJ
anesthj-143	3	14	hereditary	hereditary	ADJ
anesthj-143	3	15	coproporphyria	coproporphyria	PROPN
anesthj-143	3	16	(	(	PUNCT
anesthj-143	3	17	hcp	hcp	NOUN
anesthj-143	3	18	)	)	PUNCT
anesthj-143	3	19	is	be	AUX
anesthj-143	3	20	an	an	DET
anesthj-143	3	21	inborn	inborn	ADJ
anesthj-143	3	22	error	error	NOUN
anesthj-143	3	23	of	of	ADP
anesthj-143	3	24	metabolism	metabolism	NOUN
anesthj-143	3	25	that	that	PRON
anesthj-143	3	26	causes	cause	VERB
anesthj-143	3	27	accumulation	accumulation	NOUN
anesthj-143	3	28	of	of	ADP
anesthj-143	3	29	porphyrins	porphyrin	NOUN
anesthj-143	3	30	and	and	CCONJ
anesthj-143	3	31	porphyrin	porphyrin	NOUN
anesthj-143	3	32	precursors	precursor	NOUN
anesthj-143	3	33	,	,	PUNCT
anesthj-143	3	34	which	which	PRON
anesthj-143	3	35	can	can	AUX
anesthj-143	3	36	potentially	potentially	ADV
anesthj-143	3	37	lead	lead	VERB
anesthj-143	3	38	to	to	ADP
anesthj-143	3	39	neurotoxicity	neurotoxicity	NOUN
anesthj-143	3	40	and	and	CCONJ
anesthj-143	3	41	acute	acute	ADJ
anesthj-143	3	42	crisis	crisis	NOUN
anesthj-143	3	43	with	with	ADP
anesthj-143	3	44	introduction	introduction	NOUN
anesthj-143	3	45	of	of	ADP
anesthj-143	3	46	a	a	DET
anesthj-143	3	47	triggering	trigger	VERB
anesthj-143	3	48	agent	agent	NOUN
anesthj-143	3	49	.	.	PUNCT
anesthj-143	4	1	many	many	ADJ
anesthj-143	4	2	anesthetic	anesthetic	ADJ
anesthj-143	4	3	drugs	drug	NOUN
anesthj-143	4	4	have	have	AUX
anesthj-143	4	5	been	be	AUX
anesthj-143	4	6	labeled	label	VERB
anesthj-143	4	7	porphyrinogenic	porphyrinogenic	NOUN
anesthj-143	4	8	,	,	PUNCT
anesthj-143	4	9	therefore	therefore	ADV
anesthj-143	4	10	safe	safe	ADJ
anesthj-143	4	11	anesthetic	anesthetic	ADJ
anesthj-143	4	12	management	management	NOUN
anesthj-143	4	13	of	of	ADP
anesthj-143	4	14	patients	patient	NOUN
anesthj-143	4	15	with	with	ADP
anesthj-143	4	16	hcp	hcp	NOUN
anesthj-143	4	17	demands	demand	NOUN
anesthj-143	4	18	understanding	understanding	NOUN
anesthj-143	4	19	of	of	ADP
anesthj-143	4	20	the	the	DET
anesthj-143	4	21	disease	disease	NOUN
anesthj-143	4	22	process	process	NOUN
anesthj-143	4	23	.	.	PUNCT
anesthj-143	5	1	although	although	SCONJ
anesthj-143	5	2	most	most	ADJ
anesthj-143	5	3	of	of	ADP
anesthj-143	5	4	the	the	DET
anesthj-143	5	5	current	current	ADJ
anesthj-143	5	6	clinical	clinical	ADJ
anesthj-143	5	7	reports	report	NOUN
anesthj-143	5	8	are	be	AUX
anesthj-143	5	9	anecdotal	anecdotal	ADJ
anesthj-143	5	10	and/or	and/or	CCONJ
anesthj-143	5	11	outdated	outdated	ADJ
anesthj-143	5	12	,	,	PUNCT
anesthj-143	5	13	there	there	PRON
anesthj-143	5	14	is	be	VERB
anesthj-143	5	15	consensus	consensus	NOUN
anesthj-143	5	16	that	that	SCONJ
anesthj-143	5	17	unsafe	unsafe	ADJ
anesthj-143	5	18	agents	agent	NOUN
anesthj-143	5	19	include	include	VERB
anesthj-143	5	20	:	:	PUNCT
anesthj-143	5	21	barbiturates	barbiturate	NOUN
anesthj-143	5	22	,	,	PUNCT
anesthj-143	5	23	ketamine	ketamine	PROPN
anesthj-143	5	24	,	,	PUNCT
anesthj-143	5	25	and	and	CCONJ
anesthj-143	5	26	etomidate	etomidate	NOUN
anesthj-143	5	27	;	;	PUNCT
anesthj-143	5	28	and	and	CCONJ
anesthj-143	5	29	safe	safe	ADJ
anesthj-143	5	30	agents	agent	NOUN
anesthj-143	5	31	include	include	VERB
anesthj-143	5	32	:	:	PUNCT
anesthj-143	5	33	propofol	propofol	ADJ
anesthj-143	5	34	,	,	PUNCT
anesthj-143	5	35	nitrous	nitrous	ADJ
anesthj-143	5	36	oxide	oxide	NOUN
anesthj-143	5	37	,	,	PUNCT
anesthj-143	5	38	volatile	volatile	ADJ
anesthj-143	5	39	agents	agent	NOUN
anesthj-143	5	40	,	,	PUNCT
anesthj-143	5	41	all	all	DET
anesthj-143	5	42	neuromuscular	neuromuscular	ADJ
anesthj-143	5	43	blocking	block	VERB
anesthj-143	5	44	agents	agent	NOUN
anesthj-143	5	45	,	,	PUNCT
anesthj-143	5	46	all	all	DET
anesthj-143	5	47	reversal	reversal	NOUN
anesthj-143	5	48	agents	agent	NOUN
anesthj-143	5	49	,	,	PUNCT
anesthj-143	5	50	commonly	commonly	ADV
anesthj-143	5	51	used	use	VERB
anesthj-143	5	52	narcotics	narcotic	NOUN
anesthj-143	5	53	,	,	PUNCT
anesthj-143	5	54	antiemetics	antiemetic	NOUN
anesthj-143	5	55	(	(	PUNCT
anesthj-143	5	56	excluding	exclude	VERB
anesthj-143	5	57	metoclopramide	metoclopramide	NOUN
anesthj-143	5	58	)	)	PUNCT
anesthj-143	5	59	,	,	PUNCT
anesthj-143	5	60	and	and	CCONJ
anesthj-143	5	61	sedatives	sedative	NOUN
anesthj-143	5	62	.	.	PUNCT
anesthj-143	6	1	acute	acute	ADJ
anesthj-143	6	2	attacks	attack	NOUN
anesthj-143	6	3	of	of	ADP
anesthj-143	6	4	hcp	hcp	NOUN
anesthj-143	6	5	exhibit	exhibit	VERB
anesthj-143	6	6	a	a	DET
anesthj-143	6	7	wide	wide	ADJ
anesthj-143	6	8	variety	variety	NOUN
anesthj-143	6	9	of	of	ADP
anesthj-143	6	10	metabolic	metabolic	NOUN
anesthj-143	6	11	defects	defect	NOUN
anesthj-143	6	12	that	that	PRON
anesthj-143	6	13	may	may	AUX
anesthj-143	6	14	result	result	VERB
anesthj-143	6	15	in	in	ADP
anesthj-143	6	16	life	life	NOUN
anesthj-143	6	17	-	-	PUNCT
anesthj-143	6	18	threatening	threaten	VERB
anesthj-143	6	19	reactions	reaction	NOUN
anesthj-143	6	20	,	,	PUNCT
anesthj-143	6	21	such	such	ADJ
anesthj-143	6	22	as	as	ADP
anesthj-143	6	23	severe	severe	ADJ
anesthj-143	6	24	autonomic	autonomic	ADJ
anesthj-143	6	25	dysfunction	dysfunction	NOUN
anesthj-143	6	26	and	and	CCONJ
anesthj-143	6	27	blood	blood	NOUN
anesthj-143	6	28	pressure	pressure	NOUN
anesthj-143	6	29	(	(	PUNCT
anesthj-143	6	30	bp	bp	PROPN
anesthj-143	6	31	)	)	PUNCT
anesthj-143	6	32	lability	lability	NOUN
anesthj-143	6	33	.	.	PUNCT
anesthj-143	7	1	the	the	DET
anesthj-143	7	2	anesthesia	anesthesia	NOUN
anesthj-143	7	3	provider	provider	NOUN
anesthj-143	7	4	must	must	AUX
anesthj-143	7	5	be	be	AUX
anesthj-143	7	6	knowledgeable	knowledgeable	ADJ
anesthj-143	7	7	of	of	ADP
anesthj-143	7	8	concomitant	concomitant	ADJ
anesthj-143	7	9	triggers	trigger	NOUN
anesthj-143	7	10	as	as	ADV
anesthj-143	7	11	well	well	ADV
anesthj-143	7	12	as	as	ADP
anesthj-143	7	13	appropriate	appropriate	ADJ
anesthj-143	7	14	treatment	treatment	NOUN
anesthj-143	7	15	of	of	ADP
anesthj-143	7	16	porphyric	porphyric	ADJ
anesthj-143	7	17	crises	crisis	NOUN
anesthj-143	7	18	.	.	PUNCT
anesthj-143	8	1	further	further	ADJ
anesthj-143	8	2	investigation	investigation	NOUN
anesthj-143	8	3	of	of	ADP
anesthj-143	8	4	anesthetic	anesthetic	ADJ
anesthj-143	8	5	management	management	NOUN
anesthj-143	8	6	of	of	ADP
anesthj-143	8	7	the	the	DET
anesthj-143	8	8	patient	patient	NOUN
anesthj-143	8	9	with	with	ADP
anesthj-143	8	10	hcp	hcp	PROPN
anesthj-143	8	11	is	be	AUX
anesthj-143	8	12	indicated	indicate	VERB
anesthj-143	8	13	,	,	PUNCT
anesthj-143	8	14	given	give	VERB
anesthj-143	8	15	that	that	SCONJ
anesthj-143	8	16	most	most	ADJ
anesthj-143	8	17	current	current	ADJ
anesthj-143	8	18	clinical	clinical	ADJ
anesthj-143	8	19	reports	report	NOUN
anesthj-143	8	20	are	be	AUX
anesthj-143	8	21	anecdotal	anecdotal	ADJ
anesthj-143	8	22	and/or	and/or	CCONJ
anesthj-143	8	23	outdated	outdated	ADJ
anesthj-143	8	24	.	.	PUNCT
anesthj-143	9	1	the	the	DET
anesthj-143	9	2	anesthesia	anesthesia	NOUN
anesthj-143	9	3	provider	provider	NOUN
anesthj-143	9	4	should	should	AUX
anesthj-143	9	5	refer	refer	VERB
anesthj-143	9	6	to	to	ADP
anesthj-143	9	7	the	the	DET
anesthj-143	9	8	american	american	PROPN
anesthj-143	9	9	porphyria	porphyria	PROPN
anesthj-143	9	10	foundation	foundation	NOUN
anesthj-143	9	11	website	website	NOUN
anesthj-143	9	12	for	for	ADP
anesthj-143	9	13	the	the	DET
anesthj-143	9	14	most	most	ADJ
anesthj-143	9	15	up	up	ADP
anesthj-143	9	16	-	-	PUNCT
anesthj-143	9	17	to	to	ADP
anesthj-143	9	18	-	-	PUNCT
anesthj-143	9	19	date	date	NOUN
anesthj-143	9	20	information	information	NOUN
anesthj-143	9	21	on	on	ADP
anesthj-143	9	22	porphyria	porphyria	NOUN
anesthj-143	9	23	and	and	CCONJ
anesthj-143	9	24	up	up	ADP
anesthj-143	9	25	-	-	PUNCT
anesthj-143	9	26	to	to	ADP
anesthj-143	9	27	-	-	PUNCT
anesthj-143	9	28	date	date	NOUN
anesthj-143	9	29	drug	drug	NOUN
anesthj-143	9	30	database	database	NOUN
anesthj-143	9	31	for	for	ADP
anesthj-143	9	32	healthcare	healthcare	NOUN
anesthj-143	9	33	professionals	professional	NOUN
anesthj-143	9	34	caring	care	VERB
anesthj-143	9	35	for	for	ADP
anesthj-143	9	36	porphyria	porphyria	NOUN
anesthj-143	9	37	patients	patient	NOUN
anesthj-143	9	38	aej	aej	PROPN
anesthj-143	9	39	powerpoint	powerpoint	NOUN
anesthj-143	9	40	template	template	NOUN
anesthj-143	9	41	©	©	PROPN
anesthj-143	9	42	2009	2009	NUM
anesthj-143	9	43	texas	texas	PROPN
anesthj-143	9	44	christian	christian	PROPN
anesthj-143	9	45	university	university	PROPN
anesthj-143	9	46	,	,	PUNCT
anesthj-143	9	47	center	center	NOUN
anesthj-143	9	48	for	for	ADP
anesthj-143	9	49	instructional	instructional	ADJ
anesthj-143	9	50	services	service	NOUN
anesthj-143	9	51	.	.	PUNCT
anesthj-143	10	1	for	for	ADP
anesthj-143	10	2	educational	educational	ADJ
anesthj-143	10	3	use	use	NOUN
anesthj-143	10	4	only	only	ADV
anesthj-143	10	5	.	.	PUNCT
anesthj-143	11	1	content	content	NOUN
anesthj-143	11	2	is	be	AUX
anesthj-143	11	3	the	the	DET
anesthj-143	11	4	property	property	NOUN
anesthj-143	11	5	of	of	ADP
anesthj-143	11	6	the	the	DET
anesthj-143	11	7	presenter	presenter	NOUN
anesthj-143	11	8	and	and	CCONJ
anesthj-143	11	9	their	their	PRON
anesthj-143	11	10	resources	resource	NOUN
anesthj-143	11	11	.	.	PUNCT
anesthj-143	12	1	introduction	introduction	NOUN
anesthj-143	12	2	•	•	NUM
anesthj-143	12	3	hcp	hcp	PROPN
anesthj-143	12	4	is	be	AUX
anesthj-143	12	5	a	a	DET
anesthj-143	12	6	rare	rare	ADJ
anesthj-143	12	7	(	(	PUNCT
anesthj-143	12	8	1:1,000,000	1:1,000,000	NUM
anesthj-143	12	9	)	)	PUNCT
anesthj-143	12	10	heme	heme	NOUN
anesthj-143	12	11	biosynthesis	biosynthesis	NOUN
anesthj-143	12	12	disorder	disorder	NOUN
anesthj-143	12	13	inherited	inherit	VERB
anesthj-143	12	14	from	from	ADP
anesthj-143	12	15	either	either	DET
anesthj-143	12	16	parent	parent	NOUN
anesthj-143	12	17	via	via	ADP
anesthj-143	12	18	autosomal	autosomal	ADJ
anesthj-143	12	19	dominance	dominance	NOUN
anesthj-143	12	20	.	.	PUNCT
anesthj-143	13	1	•	•	NUM
anesthj-143	13	2	hcp	hcp	PROPN
anesthj-143	13	3	causes	cause	VERB
anesthj-143	13	4	accumulation	accumulation	NOUN
anesthj-143	13	5	of	of	ADP
anesthj-143	13	6	porphyrins	porphyrin	NOUN
anesthj-143	13	7	and	and	CCONJ
anesthj-143	13	8	porphyrin	porphyrin	NOUN
anesthj-143	13	9	precursors	precursor	NOUN
anesthj-143	13	10	which	which	PRON
anesthj-143	13	11	lead	lead	VERB
anesthj-143	13	12	to	to	ADP
anesthj-143	13	13	neurotoxicity	neurotoxicity	NOUN
anesthj-143	13	14	and	and	CCONJ
anesthj-143	13	15	subsequent	subsequent	ADJ
anesthj-143	13	16	acute	acute	ADJ
anesthj-143	13	17	attack	attack	NOUN
anesthj-143	13	18	in	in	ADP
anesthj-143	13	19	the	the	DET
anesthj-143	13	20	presence	presence	NOUN
anesthj-143	13	21	of	of	ADP
anesthj-143	13	22	known	know	VERB
anesthj-143	13	23	triggering	trigger	VERB
anesthj-143	13	24	agents	agent	NOUN
anesthj-143	13	25	.	.	PUNCT
anesthj-143	14	1	•	•	NUM
anesthj-143	14	2	acute	acute	NOUN
anesthj-143	14	3	attacks	attack	NOUN
anesthj-143	14	4	can	can	AUX
anesthj-143	14	5	be	be	AUX
anesthj-143	14	6	life	life	NOUN
anesthj-143	14	7	threatening	threaten	VERB
anesthj-143	14	8	and	and	CCONJ
anesthj-143	14	9	involve	involve	VERB
anesthj-143	14	10	severe	severe	ADJ
anesthj-143	14	11	autonomic	autonomic	ADJ
anesthj-143	14	12	instability	instability	NOUN
anesthj-143	14	13	,	,	PUNCT
anesthj-143	14	14	respiratory	respiratory	ADJ
anesthj-143	14	15	failure	failure	NOUN
anesthj-143	14	16	,	,	PUNCT
anesthj-143	14	17	and	and	CCONJ
anesthj-143	14	18	paralysis	paralysis	NOUN
anesthj-143	14	19	.	.	PUNCT
anesthj-143	15	1	•	•	NOUN
anesthj-143	15	2	triggering	trigger	VERB
anesthj-143	15	3	agents	agent	NOUN
anesthj-143	15	4	include	include	VERB
anesthj-143	15	5	many	many	ADJ
anesthj-143	15	6	anesthetic	anesthetic	ADJ
anesthj-143	15	7	agents	agent	NOUN
anesthj-143	15	8	that	that	PRON
anesthj-143	15	9	have	have	AUX
anesthj-143	15	10	been	be	AUX
anesthj-143	15	11	labeled	label	VERB
anesthj-143	15	12	porphyrinogenic	porphyrinogenic	NOUN
anesthj-143	15	13	;	;	PUNCT
anesthj-143	15	14	see	see	VERB
anesthj-143	15	15	table	table	NOUN
anesthj-143	15	16	1	1	NUM
anesthj-143	15	17	.	.	NOUN
anesthj-143	15	18	•	•	NOUN
anesthj-143	15	19	safe	safe	ADJ
anesthj-143	15	20	anesthetic	anesthetic	ADJ
anesthj-143	15	21	management	management	NOUN
anesthj-143	15	22	of	of	ADP
anesthj-143	15	23	patients	patient	NOUN
anesthj-143	15	24	with	with	ADP
anesthj-143	15	25	hcp	hcp	NOUN
anesthj-143	15	26	demands	demand	NOUN
anesthj-143	15	27	understanding	understanding	NOUN
anesthj-143	15	28	of	of	ADP
anesthj-143	15	29	this	this	DET
anesthj-143	15	30	disease	disease	NOUN
anesthj-143	15	31	process	process	NOUN
anesthj-143	15	32	.	.	PUNCT
anesthj-143	16	1	purpose	purpose	NOUN
anesthj-143	16	2	•	•	ADP
anesthj-143	16	3	this	this	DET
anesthj-143	16	4	case	case	NOUN
anesthj-143	16	5	report	report	NOUN
anesthj-143	16	6	describes	describe	VERB
anesthj-143	16	7	the	the	DET
anesthj-143	16	8	pathophysiology	pathophysiology	NOUN
anesthj-143	16	9	and	and	CCONJ
anesthj-143	16	10	anesthetic	anesthetic	ADJ
anesthj-143	16	11	management	management	NOUN
anesthj-143	16	12	of	of	ADP
anesthj-143	16	13	a	a	DET
anesthj-143	16	14	patient	patient	NOUN
anesthj-143	16	15	with	with	ADP
anesthj-143	16	16	hereditary	hereditary	ADJ
anesthj-143	16	17	coproporphyria	coproporphyria	PROPN
anesthj-143	16	18	(	(	PUNCT
anesthj-143	16	19	hcp	hcp	NOUN
anesthj-143	16	20	)	)	PUNCT
anesthj-143	16	21	.	.	PUNCT
anesthj-143	17	1	discussion	discussion	NOUN
anesthj-143	17	2	•	•	ADP
anesthj-143	17	3	the	the	DET
anesthj-143	17	4	patient	patient	NOUN
anesthj-143	17	5	was	be	AUX
anesthj-143	17	6	at	at	ADP
anesthj-143	17	7	increased	increase	VERB
anesthj-143	17	8	risk	risk	NOUN
anesthj-143	17	9	of	of	ADP
anesthj-143	17	10	an	an	DET
anesthj-143	17	11	attack	attack	NOUN
anesthj-143	17	12	of	of	ADP
anesthj-143	17	13	acute	acute	ADJ
anesthj-143	17	14	porphyria	porphyria	NOUN
anesthj-143	17	15	due	due	ADP
anesthj-143	17	16	to	to	ADP
anesthj-143	17	17	pmh	pmh	NOUN
anesthj-143	17	18	of	of	ADP
anesthj-143	17	19	hcp	hcp	NOUN
anesthj-143	17	20	combined	combine	VERB
anesthj-143	17	21	with	with	ADP
anesthj-143	17	22	the	the	DET
anesthj-143	17	23	necessity	necessity	NOUN
anesthj-143	17	24	to	to	PART
anesthj-143	17	25	undergo	undergo	VERB
anesthj-143	17	26	general	general	ADJ
anesthj-143	17	27	anesthesia	anesthesia	NOUN
anesthj-143	17	28	.	.	PUNCT
anesthj-143	18	1	•	•	NUM
anesthj-143	18	2	the	the	DET
anesthj-143	18	3	decision	decision	NOUN
anesthj-143	18	4	to	to	PART
anesthj-143	18	5	substitute	substitute	VERB
anesthj-143	18	6	the	the	DET
anesthj-143	18	7	planned	plan	VERB
anesthj-143	18	8	sevoflurane	sevoflurane	NOUN
anesthj-143	18	9	with	with	ADP
anesthj-143	18	10	isoflurane	isoflurane	NOUN
anesthj-143	18	11	was	be	AUX
anesthj-143	18	12	an	an	DET
anesthj-143	18	13	attempt	attempt	NOUN
anesthj-143	18	14	to	to	PART
anesthj-143	18	15	prevent	prevent	VERB
anesthj-143	18	16	an	an	DET
anesthj-143	18	17	exacerbation	exacerbation	NOUN
anesthj-143	18	18	of	of	ADP
anesthj-143	18	19	porphyria	porphyria	NOUN
anesthj-143	18	20	.	.	PUNCT
anesthj-143	19	1	•	•	NOUN
anesthj-143	19	2	the	the	DET
anesthj-143	19	3	patient	patient	NOUN
anesthj-143	19	4	did	do	AUX
anesthj-143	19	5	not	not	PART
anesthj-143	19	6	have	have	VERB
anesthj-143	19	7	any	any	DET
anesthj-143	19	8	porphyrinogenic	porphyrinogenic	NOUN
anesthj-143	19	9	-	-	PUNCT
anesthj-143	19	10	related	relate	VERB
anesthj-143	19	11	reactions	reaction	NOUN
anesthj-143	19	12	to	to	ADP
anesthj-143	19	13	the	the	DET
anesthj-143	19	14	anesthetic	anesthetic	ADJ
anesthj-143	19	15	agents	agent	NOUN
anesthj-143	19	16	administered	administer	VERB
anesthj-143	19	17	intraoperatively	intraoperatively	ADV
anesthj-143	19	18	.	.	PUNCT
anesthj-143	20	1	key	key	ADJ
anesthj-143	20	2	points	point	NOUN
anesthj-143	20	3	•	•	NOUN
anesthj-143	20	4	identifying	identify	VERB
anesthj-143	20	5	drugs	drug	NOUN
anesthj-143	20	6	as	as	ADP
anesthj-143	20	7	either	either	CCONJ
anesthj-143	20	8	safe	safe	ADJ
anesthj-143	20	9	or	or	CCONJ
anesthj-143	20	10	unsafe	unsafe	ADJ
anesthj-143	20	11	is	be	AUX
anesthj-143	20	12	critical	critical	ADJ
anesthj-143	20	13	.	.	PUNCT
anesthj-143	21	1	•	•	NUM
anesthj-143	21	2	anxiolysis	anxiolysis	NOUN
anesthj-143	21	3	with	with	ADP
anesthj-143	21	4	benzodiazepines	benzodiazepine	NOUN
anesthj-143	21	5	is	be	AUX
anesthj-143	21	6	recommended	recommend	VERB
anesthj-143	21	7	.	.	PUNCT
anesthj-143	22	1	•	•	NUM
anesthj-143	22	2	safe	safe	ADJ
anesthj-143	22	3	anticonvulsant	anticonvulsant	ADJ
anesthj-143	22	4	therapy	therapy	NOUN
anesthj-143	22	5	includes	include	VERB
anesthj-143	22	6	levetiracetam	levetiracetam	NOUN
anesthj-143	22	7	,	,	PUNCT
anesthj-143	22	8	clonazepam	clonazepam	NOUN
anesthj-143	22	9	,	,	PUNCT
anesthj-143	22	10	gabapentin	gabapentin	NOUN
anesthj-143	22	11	,	,	PUNCT
anesthj-143	22	12	and/or	and/or	CCONJ
anesthj-143	22	13	vigabatrin	vigabatrin	NOUN
anesthj-143	22	14	for	for	ADP
anesthj-143	22	15	seizure	seizure	NOUN
anesthj-143	22	16	prevention	prevention	NOUN
anesthj-143	22	17	.	.	PUNCT
anesthj-143	23	1	•	•	NUM
anesthj-143	23	2	correction	correction	NOUN
anesthj-143	23	3	or	or	CCONJ
anesthj-143	23	4	prevention	prevention	NOUN
anesthj-143	23	5	of	of	ADP
anesthj-143	23	6	hyponatremia	hyponatremia	PROPN
anesthj-143	23	7	and	and	CCONJ
anesthj-143	23	8	electrolyte	electrolyte	ADJ
anesthj-143	23	9	imbalances	imbalance	NOUN
anesthj-143	23	10	is	be	AUX
anesthj-143	23	11	recommended	recommend	VERB
anesthj-143	23	12	.	.	PUNCT
anesthj-143	24	1	•	•	NUM
anesthj-143	24	2	iv	iv	NUM
anesthj-143	24	3	hydration	hydration	NOUN
anesthj-143	24	4	with	with	ADP
anesthj-143	24	5	glucose	glucose	NOUN
anesthj-143	24	6	containing	contain	VERB
anesthj-143	24	7	fluids	fluid	NOUN
anesthj-143	24	8	(	(	PUNCT
anesthj-143	24	9	not	not	PART
anesthj-143	24	10	to	to	PART
anesthj-143	24	11	exceed	exceed	VERB
anesthj-143	24	12	300	300	NUM
anesthj-143	24	13	g	g	NOUN
anesthj-143	24	14	/	/	SYM
anesthj-143	24	15	day	day	NOUN
anesthj-143	24	16	)	)	PUNCT
anesthj-143	24	17	to	to	ADP
anesthj-143	24	18	downregulate	downregulate	VERB
anesthj-143	24	19	aminolaevulinic	aminolaevulinic	ADJ
anesthj-143	24	20	acid	acid	NOUN
anesthj-143	24	21	synthetase	synthetase	NOUN
anesthj-143	24	22	(	(	PUNCT
anesthj-143	24	23	alas	alas	INTJ
anesthj-143	24	24	)	)	PUNCT
anesthj-143	24	25	and	and	CCONJ
anesthj-143	24	26	to	to	PART
anesthj-143	24	27	minimize	minimize	VERB
anesthj-143	24	28	caloric	caloric	NOUN
anesthj-143	24	29	restriction	restriction	NOUN
anesthj-143	24	30	and	and	CCONJ
anesthj-143	24	31	dehydration	dehydration	NOUN
anesthj-143	24	32	.	.	PUNCT
anesthj-143	25	1	•	•	NUM
anesthj-143	25	2	general	general	ADJ
anesthj-143	25	3	and	and	CCONJ
anesthj-143	25	4	regional	regional	ADJ
anesthj-143	25	5	anesthesia	anesthesia	NOUN
anesthj-143	25	6	are	be	AUX
anesthj-143	25	7	both	both	PRON
anesthj-143	25	8	possible	possible	ADJ
anesthj-143	25	9	and	and	CCONJ
anesthj-143	25	10	equally	equally	ADV
anesthj-143	25	11	efficacious	efficacious	ADJ
anesthj-143	25	12	if	if	SCONJ
anesthj-143	25	13	initiating	initiate	VERB
anesthj-143	25	14	factors	factor	NOUN
anesthj-143	25	15	are	be	AUX
anesthj-143	25	16	avoided	avoid	VERB
anesthj-143	25	17	.	.	PUNCT
anesthj-143	26	1	•	•	NUM
anesthj-143	26	2	arterial	arterial	ADJ
anesthj-143	26	3	line	line	NOUN
anesthj-143	26	4	for	for	ADP
anesthj-143	26	5	hemodynamic	hemodynamic	ADJ
anesthj-143	26	6	monitoring	monitoring	NOUN
anesthj-143	26	7	is	be	AUX
anesthj-143	26	8	recommended	recommend	VERB
anesthj-143	26	9	due	due	ADJ
anesthj-143	26	10	to	to	ADP
anesthj-143	26	11	likelihood	likelihood	NOUN
anesthj-143	26	12	of	of	ADP
anesthj-143	26	13	autonomic	autonomic	ADJ
anesthj-143	26	14	dysfunction	dysfunction	NOUN
anesthj-143	26	15	.	.	PUNCT
anesthj-143	27	1	•	•	INTJ
anesthj-143	27	2	if	if	SCONJ
anesthj-143	27	3	a	a	DET
anesthj-143	27	4	severe	severe	ADJ
anesthj-143	27	5	attack	attack	NOUN
anesthj-143	27	6	is	be	AUX
anesthj-143	27	7	suspected	suspect	VERB
anesthj-143	27	8	,	,	PUNCT
anesthj-143	27	9	iv	iv	NUM
anesthj-143	27	10	heme	heme	NOUN
anesthj-143	27	11	(	(	PUNCT
anesthj-143	27	12	panhematin	panhematin	NOUN
anesthj-143	27	13	)	)	PUNCT
anesthj-143	27	14	should	should	AUX
anesthj-143	27	15	be	be	AUX
anesthj-143	27	16	administered	administer	VERB
anesthj-143	27	17	expeditiously	expeditiously	ADV
anesthj-143	27	18	.	.	PUNCT
anesthj-143	28	1	case	case	NOUN
anesthj-143	28	2	critique	critique	VERB
anesthj-143	28	3	•	•	ADP
anesthj-143	28	4	although	although	SCONJ
anesthj-143	28	5	the	the	DET
anesthj-143	28	6	patient	patient	NOUN
anesthj-143	28	7	was	be	AUX
anesthj-143	28	8	not	not	PART
anesthj-143	28	9	anxious	anxious	ADJ
anesthj-143	28	10	or	or	CCONJ
anesthj-143	28	11	agitated	agitated	ADJ
anesthj-143	28	12	preoperatively	preoperatively	ADV
anesthj-143	28	13	,	,	PUNCT
anesthj-143	28	14	administration	administration	NOUN
anesthj-143	28	15	of	of	ADP
anesthj-143	28	16	an	an	DET
anesthj-143	28	17	anxiolytic	anxiolytic	NOUN
anesthj-143	28	18	to	to	PART
anesthj-143	28	19	reduce	reduce	VERB
anesthj-143	28	20	stress	stress	NOUN
anesthj-143	28	21	,	,	PUNCT
anesthj-143	28	22	a	a	DET
anesthj-143	28	23	known	know	VERB
anesthj-143	28	24	trigger	trigger	NOUN
anesthj-143	28	25	of	of	ADP
anesthj-143	28	26	porphyria	porphyria	NOUN
anesthj-143	28	27	,	,	PUNCT
anesthj-143	28	28	is	be	AUX
anesthj-143	28	29	indicated	indicate	VERB
anesthj-143	28	30	.	.	PUNCT
anesthj-143	29	1	•	•	NUM
anesthj-143	29	2	the	the	DET
anesthj-143	29	3	patient	patient	NOUN
anesthj-143	29	4	received	receive	VERB
anesthj-143	29	5	dexamethasone	dexamethasone	NOUN
anesthj-143	29	6	despite	despite	SCONJ
anesthj-143	29	7	many	many	ADJ
anesthj-143	29	8	studies	study	NOUN
anesthj-143	29	9	claiming	claim	VERB
anesthj-143	29	10	it	it	PRON
anesthj-143	29	11	to	to	PART
anesthj-143	29	12	be	be	AUX
anesthj-143	29	13	unsafe	unsafe	ADJ
anesthj-143	29	14	.	.	PUNCT
anesthj-143	30	1	•	•	INTJ
anesthj-143	30	2	it	it	PRON
anesthj-143	30	3	is	be	AUX
anesthj-143	30	4	widely	widely	ADV
anesthj-143	30	5	established	establish	VERB
anesthj-143	30	6	that	that	DET
anesthj-143	30	7	sevoflurane	sevoflurane	NOUN
anesthj-143	30	8	is	be	AUX
anesthj-143	30	9	safe	safe	ADJ
anesthj-143	30	10	.	.	PUNCT
anesthj-143	31	1	anesthetic	anesthetic	ADJ
anesthj-143	31	2	management	management	NOUN
anesthj-143	31	3	of	of	ADP
anesthj-143	31	4	a	a	DET
anesthj-143	31	5	patient	patient	NOUN
anesthj-143	31	6	with	with	ADP
anesthj-143	31	7	hereditary	hereditary	ADJ
anesthj-143	31	8	coproporphyria	coproporphyria	PROPN
anesthj-143	31	9	audrey	audrey	PROPN
anesthj-143	31	10	f.	f.	PROPN
anesthj-143	31	11	fisher	fisher	PROPN
anesthj-143	31	12	,	,	PUNCT
anesthj-143	31	13	bsn	bsn	PROPN
anesthj-143	31	14	,	,	PUNCT
anesthj-143	31	15	rn	rn	PROPN
anesthj-143	31	16	,	,	PUNCT
anesthj-143	31	17	ccrn	ccrn	PROPN
anesthj-143	31	18	,	,	PUNCT
anesthj-143	31	19	texas	texas	PROPN
anesthj-143	31	20	christian	christian	PROPN
anesthj-143	31	21	university	university	PROPN
anesthj-143	31	22	case	case	NOUN
anesthj-143	31	23	description	description	NOUN
anesthj-143	31	24	•	•	ADP
anesthj-143	31	25	a	a	DET
anesthj-143	31	26	63	63	NUM
anesthj-143	31	27	-	-	PUNCT
anesthj-143	31	28	year	year	NOUN
anesthj-143	31	29	-	-	PUNCT
anesthj-143	31	30	old	old	ADJ
anesthj-143	31	31	,	,	PUNCT
anesthj-143	31	32	101	101	NUM
anesthj-143	31	33	kg	kg	NOUN
anesthj-143	31	34	,	,	PUNCT
anesthj-143	31	35	180	180	NUM
anesthj-143	31	36	cm	cm	NOUN
anesthj-143	31	37	,	,	PUNCT
anesthj-143	31	38	male	male	NOUN
anesthj-143	31	39	presented	present	VERB
anesthj-143	31	40	for	for	ADP
anesthj-143	31	41	a	a	DET
anesthj-143	31	42	right	right	ADJ
anesthj-143	31	43	parietal	parietal	ADJ
anesthj-143	31	44	temporal	temporal	ADJ
anesthj-143	31	45	craniotomy	craniotomy	NOUN
anesthj-143	31	46	for	for	ADP
anesthj-143	31	47	a	a	DET
anesthj-143	31	48	glioblastoma	glioblastoma	NOUN
anesthj-143	31	49	tumor	tumor	NOUN
anesthj-143	31	50	resection	resection	NOUN
anesthj-143	31	51	after	after	ADP
anesthj-143	31	52	suffering	suffer	VERB
anesthj-143	31	53	frequent	frequent	ADJ
anesthj-143	31	54	left	left	ADJ
anesthj-143	31	55	sided	sided	ADJ
anesthj-143	31	56	falls	fall	VERB
anesthj-143	31	57	at	at	ADP
anesthj-143	31	58	home	home	NOUN
anesthj-143	31	59	and	and	CCONJ
anesthj-143	31	60	subsequent	subsequent	ADJ
anesthj-143	31	61	loss	loss	NOUN
anesthj-143	31	62	of	of	ADP
anesthj-143	31	63	consciousness	consciousness	NOUN
anesthj-143	31	64	.	.	PUNCT
anesthj-143	32	1	pre	pre	ADJ
anesthj-143	32	2	-	-	ADJ
anesthj-143	32	3	anesthetic	anesthetic	ADJ
anesthj-143	32	4	evaluation	evaluation	NOUN
anesthj-143	32	5	•	•	ADP
anesthj-143	32	6	medical	medical	ADJ
anesthj-143	32	7	history	history	NOUN
anesthj-143	32	8	:	:	PUNCT
anesthj-143	32	9	coronary	coronary	ADJ
anesthj-143	32	10	artery	artery	NOUN
anesthj-143	32	11	disease	disease	NOUN
anesthj-143	32	12	,	,	PUNCT
anesthj-143	32	13	carotid	carotid	NOUN
anesthj-143	32	14	stenosis	stenosis	NOUN
anesthj-143	32	15	,	,	PUNCT
anesthj-143	32	16	tobacco	tobacco	NOUN
anesthj-143	32	17	use	use	NOUN
anesthj-143	32	18	,	,	PUNCT
anesthj-143	32	19	gastroparesis	gastroparesis	NOUN
anesthj-143	32	20	,	,	PUNCT
anesthj-143	32	21	pemphigus	pemphigus	NOUN
anesthj-143	32	22	vulgaris	vulgaris	NOUN
anesthj-143	32	23	,	,	PUNCT
anesthj-143	32	24	schizophrenia	schizophrenia	NOUN
anesthj-143	32	25	,	,	PUNCT
anesthj-143	32	26	and	and	CCONJ
anesthj-143	32	27	hcp	hcp	PROPN
anesthj-143	32	28	.	.	PUNCT
anesthj-143	33	1	•	•	NUM
anesthj-143	33	2	surgical	surgical	ADJ
anesthj-143	33	3	history	history	NOUN
anesthj-143	33	4	:	:	PUNCT
anesthj-143	33	5	cataract	cataract	VERB
anesthj-143	33	6	surgery	surgery	NOUN
anesthj-143	33	7	and	and	CCONJ
anesthj-143	33	8	heart	heart	NOUN
anesthj-143	33	9	catheterization	catheterization	NOUN
anesthj-143	33	10	.	.	PUNCT
anesthj-143	34	1	•	•	NUM
anesthj-143	34	2	current	current	ADJ
anesthj-143	34	3	medication	medication	NOUN
anesthj-143	34	4	regimen	regiman	NOUN
anesthj-143	34	5	:	:	PUNCT
anesthj-143	34	6	metoprolol	metoprolol	NOUN
anesthj-143	34	7	,	,	PUNCT
anesthj-143	34	8	vitamin	vitamin	NOUN
anesthj-143	34	9	c	c	NOUN
anesthj-143	34	10	,	,	PUNCT
anesthj-143	34	11	amlodipine	amlodipine	NOUN
anesthj-143	34	12	,	,	PUNCT
anesthj-143	34	13	labetalol	labetalol	NOUN
anesthj-143	34	14	,	,	PUNCT
anesthj-143	34	15	nicotine	nicotine	NOUN
anesthj-143	34	16	patch	patch	NOUN
anesthj-143	34	17	,	,	PUNCT
anesthj-143	34	18	levetiracetam	levetiracetam	NOUN
anesthj-143	34	19	,	,	PUNCT
anesthj-143	34	20	famotidine	famotidine	NOUN
anesthj-143	34	21	,	,	PUNCT
anesthj-143	34	22	dexamethasone	dexamethasone	NOUN
anesthj-143	34	23	,	,	PUNCT
anesthj-143	34	24	risperidone	risperidone	NOUN
anesthj-143	34	25	,	,	PUNCT
anesthj-143	34	26	clonazepam	clonazepam	NOUN
anesthj-143	34	27	,	,	PUNCT
anesthj-143	34	28	benztropine	benztropine	NOUN
anesthj-143	34	29	,	,	PUNCT
anesthj-143	34	30	and	and	CCONJ
anesthj-143	34	31	aspirin	aspirin	NOUN
anesthj-143	34	32	.	.	PUNCT
anesthj-143	35	1	•	•	NUM
anesthj-143	35	2	diagnostic	diagnostic	ADJ
anesthj-143	35	3	testing	testing	NOUN
anesthj-143	35	4	:	:	PUNCT
anesthj-143	35	5	mri	mri	NOUN
anesthj-143	35	6	diagnosed	diagnose	VERB
anesthj-143	35	7	7.5	7.5	NUM
anesthj-143	35	8	cm	cm	NOUN
anesthj-143	35	9	right	right	ADJ
anesthj-143	35	10	temporal	temporal	ADJ
anesthj-143	35	11	lobe	lobe	ADJ
anesthj-143	35	12	mass	mass	NOUN
anesthj-143	35	13	with	with	ADP
anesthj-143	35	14	a	a	DET
anesthj-143	35	15	left	left	ADJ
anesthj-143	35	16	midline	midline	NOUN
anesthj-143	35	17	shift	shift	NOUN
anesthj-143	35	18	of	of	ADP
anesthj-143	35	19	7	7	NUM
anesthj-143	35	20	mm	mm	NOUN
anesthj-143	35	21	,	,	PUNCT
anesthj-143	35	22	abnormal	abnormal	ADJ
anesthj-143	35	23	labs	lab	NOUN
anesthj-143	35	24	wbc	wbc	PROPN
anesthj-143	35	25	17.6	17.6	NUM
anesthj-143	35	26	and	and	CCONJ
anesthj-143	35	27	glucose	glucose	NOUN
anesthj-143	35	28	151	151	NUM
anesthj-143	35	29	.	.	PUNCT
anesthj-143	36	1	intraoperative	intraoperative	ADJ
anesthj-143	36	2	anesthetic	anesthetic	NOUN
anesthj-143	36	3	management	management	NOUN
anesthj-143	36	4	•	•	ADP
anesthj-143	36	5	pre	pre	ADJ
anesthj-143	36	6	-	-	ADJ
anesthj-143	36	7	induction	induction	ADJ
anesthj-143	36	8	vital	vital	ADJ
anesthj-143	36	9	signs	sign	NOUN
anesthj-143	36	10	:	:	PUNCT
anesthj-143	36	11	pulse	pulse	NOUN
anesthj-143	36	12	81	81	NUM
anesthj-143	36	13	in	in	ADP
anesthj-143	36	14	nsr	nsr	PROPN
anesthj-143	36	15	,	,	PUNCT
anesthj-143	36	16	bp	bp	PROPN
anesthj-143	36	17	125/78	125/78	NUM
anesthj-143	36	18	mm	mm	PROPN
anesthj-143	36	19	hg	hg	PROPN
anesthj-143	36	20	,	,	PUNCT
anesthj-143	36	21	spo2	spo2	PROPN
anesthj-143	36	22	100	100	NUM
anesthj-143	36	23	%	%	NOUN
anesthj-143	36	24	,	,	PUNCT
anesthj-143	36	25	rr	rr	PROPN
anesthj-143	36	26	20	20	NUM
anesthj-143	36	27	,	,	PUNCT
anesthj-143	36	28	and	and	CCONJ
anesthj-143	36	29	temperature	temperature	NOUN
anesthj-143	36	30	35.1	35.1	NUM
anesthj-143	36	31	°	°	NUM
anesthj-143	36	32	c	c	NOUN
anesthj-143	36	33	.	.	PUNCT
anesthj-143	37	1	•	•	NOUN
anesthj-143	37	2	general	general	ADJ
anesthj-143	37	3	anesthetic	anesthetic	ADJ
anesthj-143	37	4	induction	induction	NOUN
anesthj-143	37	5	:	:	PUNCT
anesthj-143	37	6	fentanyl	fentanyl	NOUN
anesthj-143	37	7	100	100	NUM
anesthj-143	37	8	mcg	mcg	NOUN
anesthj-143	37	9	iv	iv	NUM
anesthj-143	37	10	,	,	PUNCT
anesthj-143	37	11	lidocaine	lidocaine	NOUN
anesthj-143	37	12	100	100	NUM
anesthj-143	37	13	mg	mg	NUM
anesthj-143	37	14	iv	iv	NUM
anesthj-143	37	15	,	,	PUNCT
anesthj-143	37	16	propofol	propofol	NOUN
anesthj-143	37	17	100	100	NUM
anesthj-143	37	18	mg	mg	NUM
anesthj-143	37	19	iv	iv	NUM
anesthj-143	37	20	,	,	PUNCT
anesthj-143	37	21	and	and	CCONJ
anesthj-143	37	22	succinylcholine	succinylcholine	PROPN
anesthj-143	37	23	140	140	NUM
anesthj-143	37	24	mg	mg	NUM
anesthj-143	37	25	iv	iv	NUM
anesthj-143	37	26	.	.	PROPN
anesthj-143	37	27	•	•	NOUN
anesthj-143	37	28	8.0	8.0	NUM
anesthj-143	37	29	ett	ett	PROPN
anesthj-143	37	30	placed	place	VERB
anesthj-143	37	31	followed	follow	VERB
anesthj-143	37	32	by	by	ADP
anesthj-143	37	33	isoflurane	isoflurane	NOUN
anesthj-143	37	34	titrated	titrate	VERB
anesthj-143	37	35	to	to	ADP
anesthj-143	37	36	0.5	0.5	NUM
anesthj-143	37	37	mac	mac	PROPN
anesthj-143	37	38	.	.	PROPN
anesthj-143	37	39	•	•	NUM
anesthj-143	37	40	remifentanil	remifentanil	NOUN
anesthj-143	37	41	and	and	CCONJ
anesthj-143	37	42	phenylephrine	phenylephrine	ADJ
anesthj-143	37	43	infusions	infusion	NOUN
anesthj-143	37	44	.	.	PUNCT
anesthj-143	38	1	•	•	NUM
anesthj-143	38	2	arterial	arterial	ADJ
anesthj-143	38	3	line	line	NOUN
anesthj-143	38	4	and	and	CCONJ
anesthj-143	38	5	internal	internal	ADJ
anesthj-143	38	6	jugular	jugular	ADJ
anesthj-143	38	7	central	central	ADJ
anesthj-143	38	8	line	line	NOUN
anesthj-143	38	9	placed	place	VERB
anesthj-143	38	10	.	.	PUNCT
anesthj-143	39	1	•	•	NUM
anesthj-143	39	2	patient	patient	NOUN
anesthj-143	39	3	placed	place	VERB
anesthj-143	39	4	in	in	ADP
anesthj-143	39	5	prone	prone	ADJ
anesthj-143	39	6	position	position	NOUN
anesthj-143	39	7	with	with	ADP
anesthj-143	39	8	head	head	NOUN
anesthj-143	39	9	in	in	ADP
anesthj-143	39	10	mayfield	mayfield	PROPN
anesthj-143	39	11	keep	keep	VERB
anesthj-143	39	12	skull	skull	NOUN
anesthj-143	39	13	pins	pin	NOUN
anesthj-143	39	14	which	which	PRON
anesthj-143	39	15	were	be	AUX
anesthj-143	39	16	verified	verify	VERB
anesthj-143	39	17	and	and	CCONJ
anesthj-143	39	18	secured	secure	VERB
anesthj-143	39	19	by	by	ADP
anesthj-143	39	20	the	the	DET
anesthj-143	39	21	surgeon	surgeon	NOUN
anesthj-143	39	22	.	.	PUNCT
anesthj-143	40	1	intraoperative	intraoperative	ADJ
anesthj-143	40	2	course	course	NOUN
anesthj-143	40	3	•	•	ADP
anesthj-143	40	4	preoperatively	preoperatively	ADV
anesthj-143	40	5	patient	patient	ADJ
anesthj-143	40	6	calm	calm	ADJ
anesthj-143	40	7	,	,	PUNCT
anesthj-143	40	8	pleasantly	pleasantly	ADV
anesthj-143	40	9	confused	confused	ADJ
anesthj-143	40	10	and	and	CCONJ
anesthj-143	40	11	denied	deny	VERB
anesthj-143	40	12	discomfort	discomfort	NOUN
anesthj-143	40	13	.	.	PUNCT
anesthj-143	41	1	•	•	NUM
anesthj-143	41	2	no	no	DET
anesthj-143	41	3	signs	sign	NOUN
anesthj-143	41	4	of	of	ADP
anesthj-143	41	5	acute	acute	ADJ
anesthj-143	41	6	attack	attack	NOUN
anesthj-143	41	7	of	of	ADP
anesthj-143	41	8	porphyria	porphyria	NOUN
anesthj-143	41	9	.	.	PUNCT
anesthj-143	42	1	postoperative	postoperative	ADJ
anesthj-143	42	2	course	course	NOUN
anesthj-143	42	3	•	•	NOUN
anesthj-143	42	4	patient	patient	NOUN
anesthj-143	42	5	transported	transport	VERB
anesthj-143	42	6	to	to	PART
anesthj-143	42	7	neuro	neuro	VERB
anesthj-143	42	8	icu	icu	PROPN
anesthj-143	42	9	and	and	CCONJ
anesthj-143	42	10	remained	remain	VERB
anesthj-143	42	11	intubated	intubate	VERB
anesthj-143	42	12	on	on	ADP
anesthj-143	42	13	mechanical	mechanical	ADJ
anesthj-143	42	14	ventilator	ventilator	NOUN
anesthj-143	42	15	and	and	CCONJ
anesthj-143	42	16	fentanyl	fentanyl	ADJ
anesthj-143	42	17	,	,	PUNCT
anesthj-143	42	18	propofol	propofol	NOUN
anesthj-143	42	19	,	,	PUNCT
anesthj-143	42	20	and	and	CCONJ
anesthj-143	42	21	nicardipine	nicardipine	NOUN
anesthj-143	42	22	infusions	infusion	NOUN
anesthj-143	42	23	.	.	PUNCT
anesthj-143	43	1	references	reference	NOUN
anesthj-143	43	2	1	1	NUM
anesthj-143	43	3	.	.	PUNCT
anesthj-143	43	4	american	american	PROPN
anesthj-143	43	5	porphyria	porphyria	PROPN
anesthj-143	43	6	foundation	foundation	PROPN
anesthj-143	43	7	website	website	NOUN
anesthj-143	43	8	.	.	PUNCT
anesthj-143	44	1	updated	update	VERB
anesthj-143	44	2	2021	2021	NUM
anesthj-143	44	3	.	.	PUNCT
anesthj-143	45	1	accessed	access	VERB
anesthj-143	45	2	february	february	PROPN
anesthj-143	45	3	13	13	NUM
anesthj-143	45	4	,	,	PUNCT
anesthj-143	45	5	2021	2021	NUM
anesthj-143	45	6	.	.	PUNCT
anesthj-143	46	1	https://porphyriafoundation.org	https://porphyriafoundation.org	X
anesthj-143	46	2	.	.	NOUN
anesthj-143	47	1	2	2	NUM
anesthj-143	47	2	.	.	X
anesthj-143	47	3	jensen	jensen	PROPN
anesthj-143	47	4	nf	nf	PROPN
anesthj-143	47	5	,	,	PUNCT
anesthj-143	47	6	fiddler	fiddler	NOUN
anesthj-143	47	7	d	d	PROPN
anesthj-143	47	8	s	s	PROPN
anesthj-143	47	9	,	,	PUNCT
anesthj-143	47	10	striepe	striepe	NOUN
anesthj-143	47	11	v.	v.	ADP
anesthj-143	47	12	anesthetic	anesthetic	ADJ
anesthj-143	47	13	considerations	consideration	NOUN
anesthj-143	47	14	in	in	ADP
anesthj-143	47	15	porphyrias	porphyria	NOUN
anesthj-143	47	16	.	.	PUNCT
anesthj-143	48	1	anes	ane	NOUN
anesthj-143	48	2	analg.1995;80(3	analg.1995;80(3	NOUN
anesthj-143	48	3	)	)	PUNCT
anesthj-143	48	4	.	.	PUNCT
anesthj-143	49	1	591	591	NUM
anesthj-143	49	2	-	-	SYM
anesthj-143	49	3	599	599	NUM
anesthj-143	49	4	.	.	PUNCT
anesthj-143	50	1	3	3	X
anesthj-143	50	2	.	.	X
anesthj-143	50	3	genetic	genetic	ADJ
anesthj-143	50	4	and	and	CCONJ
anesthj-143	50	5	rare	rare	ADJ
anesthj-143	50	6	diseases	disease	NOUN
anesthj-143	50	7	information	information	NOUN
anesthj-143	50	8	center	center	NOUN
anesthj-143	50	9	website	website	NOUN
anesthj-143	50	10	.	.	PUNCT
anesthj-143	51	1	updated	update	VERB
anesthj-143	51	2	april	april	PROPN
anesthj-143	51	3	9	9	NUM
anesthj-143	51	4	,	,	PUNCT
anesthj-143	51	5	2019	2019	NUM
anesthj-143	51	6	.	.	PUNCT
anesthj-143	52	1	accessed	access	VERB
anesthj-143	52	2	february	february	PROPN
anesthj-143	52	3	15	15	NUM
anesthj-143	52	4	,	,	PUNCT
anesthj-143	52	5	2021	2021	NUM
anesthj-143	52	6	.	.	PUNCT
anesthj-143	53	1	https://rarediseases.info.nih.gov	https://rarediseases.info.nih.gov	NOUN
anesthj-143	53	2	.	.	PUNCT
anesthj-143	54	1	4	4	X
anesthj-143	54	2	.	.	X
anesthj-143	54	3	rapp	rapp	PROPN
anesthj-143	54	4	hj	hj	PROPN
anesthj-143	54	5	,	,	PUNCT
anesthj-143	54	6	james	james	PROPN
anesthj-143	54	7	m	m	PROPN
anesthj-143	54	8	,	,	PUNCT
anesthj-143	54	9	bonkovsky	bonkovsky	NOUN
anesthj-143	54	10	.	.	PUNCT
anesthj-143	55	1	anaesthesia	anaesthesia	NOUN
anesthj-143	55	2	recommendations	recommendation	NOUN
anesthj-143	55	3	for	for	ADP
anesthj-143	55	4	patients	patient	NOUN
anesthj-143	55	5	suffering	suffer	VERB
anesthj-143	55	6	from	from	ADP
anesthj-143	55	7	porphyria	porphyria	PROPN
anesthj-143	55	8	.	.	PUNCT
anesthj-143	56	1	orphan	orphan	PROPN
anesthj-143	56	2	anesthesia	anesthesia	PROPN
anesthj-143	56	3	website	website	NOUN
anesthj-143	56	4	.	.	PUNCT
anesthj-143	57	1	updated	update	VERB
anesthj-143	57	2	december	december	PROPN
anesthj-143	57	3	2014	2014	NUM
anesthj-143	57	4	.	.	PUNCT
anesthj-143	58	1	accessed	access	VERB
anesthj-143	58	2	february	february	PROPN
anesthj-143	58	3	15	15	NUM
anesthj-143	58	4	,	,	PUNCT
anesthj-143	58	5	2021	2021	NUM
anesthj-143	58	6	.	.	PUNCT
anesthj-143	59	1	https://www.orpha.net/data/patho/ans/en/porphyria_en.pdf	https://www.orpha.net/data/patho/ans/en/porphyria_en.pdf	NOUN
anesthj-143	59	2	.	.	PUNCT
anesthj-143	60	1	5	5	X
anesthj-143	60	2	.	.	X
anesthj-143	60	3	hines	hines	PROPN
anesthj-143	60	4	rl	rl	PROPN
anesthj-143	60	5	,	,	PUNCT
anesthj-143	60	6	marschall	marschall	PROPN
anesthj-143	60	7	ke	ke	PROPN
anesthj-143	60	8	.	.	PUNCT
anesthj-143	61	1	chapter	chapter	NOUN
anesthj-143	61	2	19	19	NUM
anesthj-143	61	3	:	:	PUNCT
anesthj-143	61	4	inborn	inborn	ADJ
anesthj-143	61	5	errors	error	NOUN
anesthj-143	61	6	of	of	ADP
anesthj-143	61	7	metabolism	metabolism	NOUN
anesthj-143	61	8	.	.	PUNCT
anesthj-143	62	1	in	in	ADP
anesthj-143	62	2	:	:	PUNCT
anesthj-143	62	3	tantawy	tantawy	ADJ
anesthj-143	62	4	h	h	PROPN
anesthj-143	62	5	,	,	PUNCT
anesthj-143	62	6	tao	tao	PROPN
anesthj-143	62	7	j.	j.	PROPN
anesthj-143	62	8	stoelting	stoelting	PROPN
anesthj-143	62	9	’s	’s	PART
anesthj-143	62	10	anesthesia	anesthesia	NOUN
anesthj-143	62	11	and	and	CCONJ
anesthj-143	62	12	co	co	ADJ
anesthj-143	62	13	-	-	ADJ
anesthj-143	62	14	existing	exist	VERB
anesthj-143	62	15	disease	disease	NOUN
anesthj-143	62	16	.	.	PUNCT
anesthj-143	63	1	7th	7th	ADJ
anesthj-143	63	2	ed	ed	NOUN
anesthj-143	63	3	.	.	PUNCT
anesthj-143	64	1	elsevier	elsevier	PROPN
anesthj-143	64	2	inc	inc	PROPN
anesthj-143	64	3	;	;	PUNCT
anesthj-143	64	4	2018:377	2018:377	NUM
anesthj-143	64	5	-	-	SYM
anesthj-143	64	6	384	384	NUM
anesthj-143	64	7	.	.	NOUN
anesthj-143	64	8	6	6	NUM
anesthj-143	64	9	.	.	X
anesthj-143	64	10	findley	findley	PROPN
anesthj-143	64	11	h	h	PROPN
anesthj-143	64	12	,	,	PUNCT
anesthj-143	64	13	philips	philips	PROPN
anesthj-143	64	14	a	a	PRON
anesthj-143	64	15	,	,	PUNCT
anesthj-143	64	16	cole	cole	PROPN
anesthj-143	64	17	d	d	PROPN
anesthj-143	64	18	,	,	PUNCT
anesthj-143	64	19	nair	nair	PROPN
anesthj-143	64	20	a.	a.	NOUN
anesthj-143	64	21	porphyrias	porphyrias	PROPN
anesthj-143	64	22	:	:	PUNCT
anesthj-143	64	23	implications	implication	NOUN
anesthj-143	64	24	for	for	ADP
anesthj-143	64	25	anaesthesia	anaesthesia	NOUN
anesthj-143	64	26	,	,	PUNCT
anesthj-143	64	27	critical	critical	ADJ
anesthj-143	64	28	care	care	NOUN
anesthj-143	64	29	,	,	PUNCT
anesthj-143	64	30	and	and	CCONJ
anesthj-143	64	31	pain	pain	NOUN
anesthj-143	64	32	medicine	medicine	NOUN
anesthj-143	64	33	.	.	PUNCT
anesthj-143	65	1	continuing	continue	VERB
anesthj-143	65	2	educ	educ	PROPN
anesthj-143	65	3	anes	ane	NOUN
anesthj-143	65	4	crit	crit	PROPN
anesthj-143	65	5	care	care	NOUN
anesthj-143	65	6	pain	pain	NOUN
anesthj-143	65	7	.	.	PUNCT
anesthj-143	66	1	2012;12(3	2012;12(3	NUM
anesthj-143	66	2	)	)	PUNCT
anesthj-143	66	3	.	.	PUNCT
anesthj-143	67	1	128	128	NUM
anesthj-143	67	2	-	-	SYM
anesthj-143	67	3	133	133	NUM
anesthj-143	67	4	.	.	PUNCT
anesthj-143	68	1	conclusions	conclusion	NOUN
anesthj-143	68	2	and	and	CCONJ
anesthj-143	68	3	recommendations	recommendation	NOUN
anesthj-143	68	4	•	•	ADP
anesthj-143	68	5	a	a	DET
anesthj-143	68	6	thorough	thorough	ADJ
anesthj-143	68	7	perioperative	perioperative	ADJ
anesthj-143	68	8	workup	workup	NOUN
anesthj-143	68	9	must	must	AUX
anesthj-143	68	10	be	be	AUX
anesthj-143	68	11	performed	perform	VERB
anesthj-143	68	12	in	in	ADP
anesthj-143	68	13	order	order	NOUN
anesthj-143	68	14	to	to	PART
anesthj-143	68	15	prevent	prevent	VERB
anesthj-143	68	16	an	an	DET
anesthj-143	68	17	acute	acute	ADJ
anesthj-143	68	18	attack	attack	NOUN
anesthj-143	68	19	of	of	ADP
anesthj-143	68	20	porphyria	porphyria	NOUN
anesthj-143	68	21	which	which	PRON
anesthj-143	68	22	can	can	AUX
anesthj-143	68	23	be	be	AUX
anesthj-143	68	24	life	life	NOUN
anesthj-143	68	25	-	-	PUNCT
anesthj-143	68	26	threatening	threatening	ADJ
anesthj-143	68	27	.	.	PUNCT
anesthj-143	69	1	•	•	NUM
anesthj-143	69	2	determination	determination	NOUN
anesthj-143	69	3	of	of	ADP
anesthj-143	69	4	safe	safe	ADJ
anesthj-143	69	5	vs	vs	ADP
anesthj-143	69	6	unsafe	unsafe	ADJ
anesthj-143	69	7	anesthetic	anesthetic	ADJ
anesthj-143	69	8	medications	medication	NOUN
anesthj-143	69	9	is	be	AUX
anesthj-143	69	10	key	key	ADJ
anesthj-143	69	11	.	.	PUNCT
anesthj-143	70	1	•	•	NUM
anesthj-143	70	2	no	no	DET
anesthj-143	70	3	evidence	evidence	NOUN
anesthj-143	70	4	suggests	suggest	VERB
anesthj-143	70	5	a	a	DET
anesthj-143	70	6	general	general	ADJ
anesthj-143	70	7	anesthetic	anesthetic	NOUN
anesthj-143	70	8	is	be	AUX
anesthj-143	70	9	safer	safe	ADJ
anesthj-143	70	10	than	than	ADP
anesthj-143	70	11	a	a	DET
anesthj-143	70	12	regional	regional	ADJ
anesthj-143	70	13	anesthetic	anesthetic	NOUN
anesthj-143	70	14	.	.	PUNCT
anesthj-143	71	1	•	•	NUM
anesthj-143	71	2	further	further	ADJ
anesthj-143	71	3	investigation	investigation	NOUN
anesthj-143	71	4	of	of	ADP
anesthj-143	71	5	anesthetic	anesthetic	ADJ
anesthj-143	71	6	management	management	NOUN
anesthj-143	71	7	of	of	ADP
anesthj-143	71	8	the	the	DET
anesthj-143	71	9	patient	patient	NOUN
anesthj-143	71	10	with	with	ADP
anesthj-143	71	11	hcp	hcp	PROPN
anesthj-143	71	12	is	be	AUX
anesthj-143	71	13	required	require	VERB
anesthj-143	71	14	because	because	SCONJ
anesthj-143	71	15	most	most	ADJ
anesthj-143	71	16	of	of	ADP
anesthj-143	71	17	the	the	DET
anesthj-143	71	18	current	current	ADJ
anesthj-143	71	19	clinical	clinical	ADJ
anesthj-143	71	20	reports	report	NOUN
anesthj-143	71	21	are	be	AUX
anesthj-143	71	22	anecdotal	anecdotal	ADJ
anesthj-143	71	23	and/or	and/or	CCONJ
anesthj-143	71	24	outdated	outdated	ADJ
anesthj-143	71	25	.	.	PUNCT
anesthj-143	72	1	•	•	NUM
anesthj-143	72	2	refer	refer	VERB
anesthj-143	72	3	to	to	ADP
anesthj-143	72	4	the	the	DET
anesthj-143	72	5	american	american	PROPN
anesthj-143	72	6	porphyria	porphyria	PROPN
anesthj-143	72	7	foundation	foundation	NOUN
anesthj-143	72	8	website	website	NOUN
anesthj-143	72	9	for	for	ADP
anesthj-143	72	10	the	the	DET
anesthj-143	72	11	most	most	ADJ
anesthj-143	72	12	up	up	ADP
anesthj-143	72	13	-	-	PUNCT
anesthj-143	72	14	to	to	ADP
anesthj-143	72	15	-	-	PUNCT
anesthj-143	72	16	date	date	NOUN
anesthj-143	72	17	information	information	NOUN
anesthj-143	72	18	on	on	ADP
anesthj-143	72	19	porphyria	porphyria	NOUN
anesthj-143	72	20	and	and	CCONJ
anesthj-143	72	21	up	up	ADP
anesthj-143	72	22	-	-	PUNCT
anesthj-143	72	23	to	to	ADP
anesthj-143	72	24	-	-	PUNCT
anesthj-143	72	25	date	date	NOUN
anesthj-143	72	26	drug	drug	NOUN
anesthj-143	72	27	database	database	NOUN
anesthj-143	72	28	for	for	ADP
anesthj-143	72	29	healthcare	healthcare	NOUN
anesthj-143	72	30	professionals	professional	NOUN
anesthj-143	72	31	.	.	PUNCT
anesthj-143	73	1	pathophysiology	pathophysiology	NOUN
anesthj-143	73	2	and	and	CCONJ
anesthj-143	73	3	manifestations	manifestation	NOUN
anesthj-143	73	4	•	•	PRON
anesthj-143	73	5	heme	heme	NOUN
anesthj-143	73	6	is	be	AUX
anesthj-143	73	7	a	a	DET
anesthj-143	73	8	vital	vital	ADJ
anesthj-143	73	9	porphyrin	porphyrin	NOUN
anesthj-143	73	10	to	to	ADP
anesthj-143	73	11	hemoglobin	hemoglobin	NOUN
anesthj-143	73	12	because	because	SCONJ
anesthj-143	73	13	it	it	PRON
anesthj-143	73	14	is	be	AUX
anesthj-143	73	15	required	require	VERB
anesthj-143	73	16	to	to	PART
anesthj-143	73	17	transport	transport	VERB
anesthj-143	73	18	o2	o2	PROPN
anesthj-143	73	19	,	,	PUNCT
anesthj-143	73	20	remove	remove	VERB
anesthj-143	73	21	co2	co2	NOUN
anesthj-143	73	22	,	,	PUNCT
anesthj-143	73	23	and	and	CCONJ
anesthj-143	73	24	biotransform	biotransform	VERB
anesthj-143	73	25	essential	essential	ADJ
anesthj-143	73	26	enzymes	enzyme	NOUN
anesthj-143	73	27	such	such	ADJ
anesthj-143	73	28	as	as	ADP
anesthj-143	73	29	cyp450	cyp450	NOUN
anesthj-143	73	30	;	;	PUNCT
anesthj-143	73	31	see	see	VERB
anesthj-143	73	32	figure	figure	NOUN
anesthj-143	73	33	2	2	NUM
anesthj-143	73	34	.	.	NOUN
anesthj-143	73	35	•	•	NUM
anesthj-143	73	36	the	the	DET
anesthj-143	73	37	porphyrias	porphyria	NOUN
anesthj-143	73	38	,	,	PUNCT
anesthj-143	73	39	a	a	DET
anesthj-143	73	40	group	group	NOUN
anesthj-143	73	41	of	of	ADP
anesthj-143	73	42	metabolic	metabolic	NOUN
anesthj-143	73	43	disorders	disorder	NOUN
anesthj-143	73	44	,	,	PUNCT
anesthj-143	73	45	each	each	PRON
anesthj-143	73	46	lack	lack	VERB
anesthj-143	73	47	any	any	DET
anesthj-143	73	48	1	1	NUM
anesthj-143	73	49	of	of	ADP
anesthj-143	73	50	the	the	DET
anesthj-143	73	51	8	8	NUM
anesthj-143	73	52	enzymes	enzyme	NOUN
anesthj-143	73	53	in	in	ADP
anesthj-143	73	54	the	the	DET
anesthj-143	73	55	heme	heme	NOUN
anesthj-143	73	56	synthetic	synthetic	ADJ
anesthj-143	73	57	pathway	pathway	NOUN
anesthj-143	73	58	resulting	result	VERB
anesthj-143	73	59	in	in	ADP
anesthj-143	73	60	the	the	DET
anesthj-143	73	61	accumulation	accumulation	NOUN
anesthj-143	73	62	of	of	ADP
anesthj-143	73	63	porphyrin	porphyrin	NOUN
anesthj-143	73	64	and	and	CCONJ
anesthj-143	73	65	porphyrin	porphyrin	NOUN
anesthj-143	73	66	precursors	precursor	NOUN
anesthj-143	73	67	ala	ala	PROPN
anesthj-143	73	68	and	and	CCONJ
anesthj-143	73	69	pbg	pbg	PROPN
anesthj-143	73	70	,	,	PUNCT
anesthj-143	73	71	subsequently	subsequently	ADV
anesthj-143	73	72	producing	produce	VERB
anesthj-143	73	73	a	a	DET
anesthj-143	73	74	form	form	NOUN
anesthj-143	73	75	of	of	ADP
anesthj-143	73	76	porphyria	porphyria	NOUN
anesthj-143	73	77	;	;	PUNCT
anesthj-143	73	78	see	see	VERB
anesthj-143	73	79	figure	figure	NOUN
anesthj-143	73	80	1	1	NUM
anesthj-143	73	81	.	.	NOUN
anesthj-143	73	82	•	•	NUM
anesthj-143	73	83	hcp	hcp	PROPN
anesthj-143	73	84	lacks	lack	VERB
anesthj-143	73	85	cpo	cpo	PROPN
anesthj-143	73	86	,	,	PUNCT
anesthj-143	73	87	the	the	DET
anesthj-143	73	88	6th	6th	ADJ
anesthj-143	73	89	enzyme	enzyme	NOUN
anesthj-143	73	90	in	in	ADP
anesthj-143	73	91	the	the	DET
anesthj-143	73	92	heme	heme	NOUN
anesthj-143	73	93	biosynthesis	biosynthesis	NOUN
anesthj-143	73	94	pathway	pathway	NOUN
anesthj-143	73	95	,	,	PUNCT
anesthj-143	73	96	which	which	PRON
anesthj-143	73	97	originates	originate	VERB
anesthj-143	73	98	from	from	ADP
anesthj-143	73	99	a	a	DET
anesthj-143	73	100	genetic	genetic	ADJ
anesthj-143	73	101	mutation	mutation	NOUN
anesthj-143	73	102	of	of	ADP
anesthj-143	73	103	the	the	DET
anesthj-143	73	104	cpox	cpox	NOUN
anesthj-143	73	105	gene	gene	NOUN
anesthj-143	73	106	on	on	ADP
anesthj-143	73	107	chromosome	chromosome	NOUN
anesthj-143	73	108	3	3	NUM
anesthj-143	73	109	;	;	PUNCT
anesthj-143	73	110	see	see	VERB
anesthj-143	73	111	figure	figure	NOUN
anesthj-143	73	112	3	3	NUM
anesthj-143	73	113	.	.	NOUN
anesthj-143	73	114	•	•	NUM
anesthj-143	73	115	manifestations	manifestation	NOUN
anesthj-143	73	116	:	:	PUNCT
anesthj-143	73	117	acute	acute	ADJ
anesthj-143	73	118	abdominal	abdominal	ADJ
anesthj-143	73	119	pain	pain	NOUN
anesthj-143	73	120	,	,	PUNCT
anesthj-143	73	121	cutaneous	cutaneous	ADJ
anesthj-143	73	122	lesions	lesion	NOUN
anesthj-143	73	123	,	,	PUNCT
anesthj-143	73	124	neuropsychiatric	neuropsychiatric	ADJ
anesthj-143	73	125	abnormalities	abnormality	NOUN
anesthj-143	73	126	such	such	ADJ
anesthj-143	73	127	as	as	ADP
anesthj-143	73	128	confusion	confusion	NOUN
anesthj-143	73	129	,	,	PUNCT
anesthj-143	73	130	seizures	seizure	NOUN
anesthj-143	73	131	,	,	PUNCT
anesthj-143	73	132	mood	mood	NOUN
anesthj-143	73	133	disturbance	disturbance	NOUN
anesthj-143	73	134	,	,	PUNCT
anesthj-143	73	135	hysteria	hysteria	NOUN
anesthj-143	73	136	,	,	PUNCT
anesthj-143	73	137	syncope	syncope	NOUN
anesthj-143	73	138	,	,	PUNCT
anesthj-143	73	139	autonomic	autonomic	ADJ
anesthj-143	73	140	instability	instability	NOUN
anesthj-143	73	141	,	,	PUNCT
anesthj-143	73	142	peripheral	peripheral	ADJ
anesthj-143	73	143	neuropathy	neuropathy	ADJ
anesthj-143	73	144	,	,	PUNCT
anesthj-143	73	145	sensory	sensory	ADJ
anesthj-143	73	146	loss	loss	NOUN
anesthj-143	73	147	and	and	CCONJ
anesthj-143	73	148	ascending	ascend	VERB
anesthj-143	73	149	muscle	muscle	NOUN
anesthj-143	73	150	weakness	weakness	NOUN
anesthj-143	73	151	mimicking	mimic	VERB
anesthj-143	73	152	guillain	guillain	NOUN
anesthj-143	73	153	-	-	PUNCT
anesthj-143	73	154	barre	barre	NOUN
anesthj-143	73	155	;	;	PUNCT
anesthj-143	73	156	see	see	VERB
anesthj-143	73	157	figure	figure	NOUN
anesthj-143	73	158	4	4	NUM
anesthj-143	73	159	.	.	PUNCT
anesthj-143	74	1	cpox	cpox	NOUN
anesthj-143	74	2	gene	gene	NOUN
anesthj-143	74	3	mutation	mutation	NOUN
anesthj-143	74	4	on	on	ADP
anesthj-143	74	5	chromosome	chromosome	NOUN
anesthj-143	74	6	3	3	NUM
anesthj-143	74	7	at	at	ADP
anesthj-143	74	8	position	position	NOUN
anesthj-143	74	9	12	12	NUM
anesthj-143	74	10	vs	vs	ADP
anesthj-143	74	11	safe	safe	ADJ
anesthj-143	74	12	agents	agent	NOUN
anesthj-143	74	13	•propofol	•propofol	PROPN
anesthj-143	74	14	•nitrous	•nitrous	ADJ
anesthj-143	74	15	oxide	oxide	NOUN
anesthj-143	74	16	•volatile	•volatile	PROPN
anesthj-143	74	17	agents	agent	NOUN
anesthj-143	74	18	•depolarizing	•depolarize	VERB
anesthj-143	74	19	and	and	CCONJ
anesthj-143	74	20	nondepolarizing	nondepolarize	VERB
anesthj-143	74	21	nmb	nmb	NOUN
anesthj-143	74	22	•reversal	•reversal	PROPN
anesthj-143	74	23	agents	agent	NOUN
anesthj-143	74	24	•antiemetics	•antiemetics	PROPN
anesthj-143	74	25	(	(	PUNCT
anesthj-143	74	26	excluding	exclude	VERB
anesthj-143	74	27	reglan	reglan	NOUN
anesthj-143	74	28	)	)	PUNCT
anesthj-143	75	1	*	*	PUNCT
anesthj-143	75	2	unsafe	unsafe	ADJ
anesthj-143	75	3	agents	agent	NOUN
anesthj-143	75	4	•barbiturates	•barbiturates	PROPN
anesthj-143	75	5	•ketamine	•ketamine	ADP
anesthj-143	75	6	•etomidate	•etomidate	PROPN
anesthj-143	75	7	•decadron	•decadron	PROPN
anesthj-143	75	8	*	*	PUNCT
anesthj-143	75	9	•calcium	•calcium	PROPN
anesthj-143	75	10	channel	channel	NOUN
anesthj-143	75	11	blockers	blocker	NOUN
anesthj-143	75	12	*	*	PUNCT
anesthj-143	75	13	•ketorolac	•ketorolac	PROPN
anesthj-143	75	14	*	*	NOUN
anesthj-143	75	15	potential	potential	NOUN
anesthj-143	75	16	of	of	ADP
anesthj-143	75	17	drugs	drug	NOUN
anesthj-143	75	18	to	to	PART
anesthj-143	75	19	provoke	provoke	VERB
anesthj-143	75	20	hcp	hcp	NOUN
anesthj-143	75	21	attacks	attack	NOUN
anesthj-143	75	22	*	*	PUNCT
anesthj-143	75	23	majority	majority	NOUN
anesthj-143	75	24	consensus	consensus	NOUN
anesthj-143	75	25	table	table	NOUN
anesthj-143	75	26	1	1	NUM
anesthj-143	75	27	.	.	PUNCT
anesthj-143	75	28	triggering	trigger	VERB
anesthj-143	75	29	agents	agent	NOUN
anesthj-143	75	30	figure	figure	VERB
anesthj-143	75	31	1	1	NUM
anesthj-143	75	32	.	.	PUNCT
anesthj-143	75	33	heme	heme	ADJ
anesthj-143	75	34	synthesis	synthesis	NOUN
anesthj-143	75	35	pathway	pathway	NOUN
anesthj-143	75	36	figure	figure	NOUN
anesthj-143	75	37	2	2	NUM
anesthj-143	75	38	.	.	PUNCT
anesthj-143	75	39	hemoglobin	hemoglobin	NOUN
anesthj-143	75	40	molecule	molecule	NOUN
anesthj-143	75	41	figure	figure	NOUN
anesthj-143	75	42	3	3	NUM
anesthj-143	75	43	.	.	PUNCT
anesthj-143	75	44	location	location	NOUN
anesthj-143	75	45	of	of	ADP
anesthj-143	75	46	cpox	cpox	NOUN
anesthj-143	75	47	gene	gene	NOUN
anesthj-143	75	48	mutation	mutation	NOUN
anesthj-143	75	49	figure	figure	NOUN
anesthj-143	75	50	4	4	NUM
anesthj-143	75	51	.	.	PUNCT
anesthj-143	75	52	apparent	apparent	ADJ
anesthj-143	75	53	vs	vs	ADP
anesthj-143	75	54	nonapparent	nonapparent	ADJ
anesthj-143	75	55	symptoms	symptom	NOUN