id	sid	tid	token	lemma	pos
anesthj-168	1	1	texas	texas	PROPN
anesthj-168	1	2	christian	christian	PROPN
anesthj-168	1	3	university	university	PROPN
anesthj-168	1	4	“	"	PUNCT
anesthj-168	1	5	the	the	DET
anesthj-168	1	6	science	science	NOUN
anesthj-168	1	7	behind	behind	ADP
anesthj-168	1	8	the	the	DET
anesthj-168	1	9	art	art	NOUN
anesthj-168	1	10	”	"	PUNCT
anesthj-168	1	11	volume	volume	NOUN
anesthj-168	1	12	10	10	NUM
anesthj-168	1	13	no.3	no.3	VERB
anesthj-168	1	14	2022	2022	NUM
anesthj-168	1	15	anesthesia	anesthesia	PROPN
anesthj-168	1	16	ejournal	ejournal	PROPN
anesthj-168	1	17	online	online	PROPN
anesthj-168	1	18	issn	issn	PROPN
anesthj-168	1	19	2333	2333	NUM
anesthj-168	1	20	-	-	SYM
anesthj-168	1	21	2611	2611	NUM
anesthj-168	1	22	page	page	NOUN
anesthj-168	1	23	3	3	NUM
anesthj-168	1	24	protamine	protamine	NOUN
anesthj-168	1	25	reaction	reaction	NOUN
anesthj-168	1	26	in	in	ADP
anesthj-168	1	27	cardiovascular	cardiovascular	ADJ
anesthj-168	1	28	surgery	surgery	NOUN
anesthj-168	1	29	gage	gage	NOUN
anesthj-168	1	30	walker	walker	PROPN
anesthj-168	1	31	,	,	PUNCT
anesthj-168	1	32	bsn	bsn	PROPN
anesthj-168	1	33	,	,	PUNCT
anesthj-168	1	34	rn	rn	PROPN
anesthj-168	1	35	,	,	PUNCT
anesthj-168	1	36	ccrn	ccrn	NOUN
anesthj-168	1	37	affiliation	affiliation	NOUN
anesthj-168	1	38	:	:	PUNCT
anesthj-168	1	39	texas	texas	PROPN
anesthj-168	1	40	christian	christian	PROPN
anesthj-168	1	41	university	university	PROPN
anesthj-168	1	42	grant	grant	NOUN
anesthj-168	1	43	/	/	SYM
anesthj-168	1	44	financial	financial	ADJ
anesthj-168	1	45	support	support	NOUN
anesthj-168	1	46	:	:	PUNCT
anesthj-168	1	47	none	none	NOUN
anesthj-168	1	48	keywords	keyword	VERB
anesthj-168	1	49	:	:	PUNCT
anesthj-168	1	50	protamine	protamine	NOUN
anesthj-168	1	51	reaction	reaction	NOUN
anesthj-168	1	52	,	,	PUNCT
anesthj-168	1	53	cardiovascular	cardiovascular	ADJ
anesthj-168	1	54	surgery	surgery	NOUN
anesthj-168	1	55	,	,	PUNCT
anesthj-168	1	56	coronary	coronary	ADJ
anesthj-168	1	57	artery	artery	NOUN
anesthj-168	1	58	bypass	bypass	NOUN
anesthj-168	1	59	abstract	abstract	ADJ
anesthj-168	1	60	coronary	coronary	ADJ
anesthj-168	1	61	artery	artery	NOUN
anesthj-168	1	62	bypass	bypass	NOUN
anesthj-168	1	63	grafting	grafting	NOUN
anesthj-168	1	64	is	be	AUX
anesthj-168	1	65	the	the	DET
anesthj-168	1	66	most	most	ADV
anesthj-168	1	67	performed	perform	VERB
anesthj-168	1	68	cardiac	cardiac	ADJ
anesthj-168	1	69	surgery	surgery	NOUN
anesthj-168	1	70	throughout	throughout	ADP
anesthj-168	1	71	the	the	DET
anesthj-168	1	72	world	world	NOUN
anesthj-168	1	73	today	today	NOUN
anesthj-168	1	74	.	.	PUNCT
anesthj-168	2	1	the	the	DET
anesthj-168	2	2	united	united	PROPN
anesthj-168	2	3	states	states	PROPN
anesthj-168	2	4	alone	alone	ADV
anesthj-168	2	5	performs	perform	VERB
anesthj-168	2	6	over	over	ADP
anesthj-168	2	7	200,000	200,000	NUM
anesthj-168	2	8	of	of	ADP
anesthj-168	2	9	these	these	DET
anesthj-168	2	10	procedures	procedure	NOUN
anesthj-168	2	11	every	every	DET
anesthj-168	2	12	year	year	NOUN
anesthj-168	2	13	.	.	PUNCT
anesthj-168	3	1	protamine	protamine	ADJ
anesthj-168	3	2	sulfate	sulfate	NOUN
anesthj-168	3	3	is	be	AUX
anesthj-168	3	4	administered	administer	VERB
anesthj-168	3	5	to	to	PART
anesthj-168	3	6	neutralize	neutralize	VERB
anesthj-168	3	7	heparin	heparin	NOUN
anesthj-168	3	8	given	give	VERB
anesthj-168	3	9	during	during	ADP
anesthj-168	3	10	these	these	DET
anesthj-168	3	11	cases	case	NOUN
anesthj-168	3	12	.	.	PUNCT
anesthj-168	4	1	known	know	VERB
anesthj-168	4	2	hemodynamic	hemodynamic	ADJ
anesthj-168	4	3	effects	effect	NOUN
anesthj-168	4	4	are	be	AUX
anesthj-168	4	5	associated	associate	VERB
anesthj-168	4	6	with	with	ADP
anesthj-168	4	7	protamine	protamine	NOUN
anesthj-168	4	8	and	and	CCONJ
anesthj-168	4	9	on	on	ADP
anesthj-168	4	10	rare	rare	ADJ
anesthj-168	4	11	occasions	occasion	NOUN
anesthj-168	4	12	,	,	PUNCT
anesthj-168	4	13	true	true	ADJ
anesthj-168	4	14	anaphylaxis	anaphylaxis	ADJ
anesthj-168	4	15	.	.	PUNCT
anesthj-168	5	1	a	a	DET
anesthj-168	5	2	10.7	10.7	NUM
anesthj-168	5	3	%	%	NOUN
anesthj-168	5	4	chance	chance	NOUN
anesthj-168	5	5	exists	exist	VERB
anesthj-168	5	6	of	of	ADP
anesthj-168	5	7	a	a	DET
anesthj-168	5	8	protamine	protamine	NOUN
anesthj-168	5	9	reaction	reaction	NOUN
anesthj-168	5	10	occurring	occur	VERB
anesthj-168	5	11	after	after	ADP
anesthj-168	5	12	its	its	PRON
anesthj-168	5	13	administration	administration	NOUN
anesthj-168	5	14	and	and	CCONJ
anesthj-168	5	15	five	five	NUM
anesthj-168	5	16	different	different	ADJ
anesthj-168	5	17	risk	risk	NOUN
anesthj-168	5	18	factors	factor	NOUN
anesthj-168	5	19	that	that	PRON
anesthj-168	5	20	increase	increase	VERB
anesthj-168	5	21	that	that	DET
anesthj-168	5	22	chance	chance	NOUN
anesthj-168	5	23	is	be	AUX
anesthj-168	5	24	an	an	DET
anesthj-168	5	25	allergy	allergy	NOUN
anesthj-168	5	26	to	to	ADP
anesthj-168	5	27	fish	fish	NOUN
anesthj-168	5	28	,	,	PUNCT
anesthj-168	5	29	use	use	NOUN
anesthj-168	5	30	of	of	ADP
anesthj-168	5	31	nph	nph	NOUN
anesthj-168	5	32	insulins	insulin	NOUN
anesthj-168	5	33	,	,	PUNCT
anesthj-168	5	34	previous	previous	ADJ
anesthj-168	5	35	vasectomy	vasectomy	NOUN
anesthj-168	5	36	,	,	PUNCT
anesthj-168	5	37	previous	previous	ADJ
anesthj-168	5	38	exposure	exposure	NOUN
anesthj-168	5	39	to	to	ADP
anesthj-168	5	40	protamine	protamine	NOUN
anesthj-168	5	41	,	,	PUNCT
anesthj-168	5	42	and	and	CCONJ
anesthj-168	5	43	rapid	rapid	ADJ
anesthj-168	5	44	administration	administration	NOUN
anesthj-168	5	45	of	of	ADP
anesthj-168	5	46	protamine	protamine	PROPN
anesthj-168	5	47	.	.	PUNCT
anesthj-168	6	1	treatment	treatment	NOUN
anesthj-168	6	2	includes	include	VERB
anesthj-168	6	3	fluid	fluid	ADJ
anesthj-168	6	4	resuscitation	resuscitation	NOUN
anesthj-168	6	5	,	,	PUNCT
anesthj-168	6	6	administration	administration	NOUN
anesthj-168	6	7	of	of	ADP
anesthj-168	6	8	vasopressors	vasopressor	NOUN
anesthj-168	6	9	,	,	PUNCT
anesthj-168	6	10	intra	intra	ADJ
anesthj-168	6	11	-	-	ADJ
anesthj-168	6	12	aortic	aortic	ADJ
anesthj-168	6	13	balloon	balloon	NOUN
anesthj-168	6	14	pump	pump	NOUN
anesthj-168	6	15	,	,	PUNCT
anesthj-168	6	16	and	and	CCONJ
anesthj-168	6	17	methylene	methylene	ADJ
anesthj-168	6	18	blue	blue	NOUN
anesthj-168	6	19	but	but	CCONJ
anesthj-168	6	20	this	this	PRON
anesthj-168	6	21	has	have	AUX
anesthj-168	6	22	not	not	PART
anesthj-168	6	23	been	be	AUX
anesthj-168	6	24	studied	study	VERB
anesthj-168	6	25	.	.	PUNCT
anesthj-168	7	1	a	a	DET
anesthj-168	7	2	heparin	heparin	ADJ
anesthj-168	7	3	removal	removal	NOUN
anesthj-168	7	4	device	device	NOUN
anesthj-168	7	5	as	as	ADP
anesthj-168	7	6	an	an	DET
anesthj-168	7	7	alternative	alternative	NOUN
anesthj-168	7	8	to	to	ADP
anesthj-168	7	9	protamine	protamine	NOUN
anesthj-168	7	10	shows	show	NOUN
anesthj-168	7	11	promise	promise	VERB
anesthj-168	7	12	.	.	PUNCT
anesthj-168	8	1	aej	aej	PROPN
anesthj-168	8	2	volume	volume	NOUN
anesthj-168	8	3	10no	10no	NOUN
anesthj-168	8	4	.	.	PUNCT
anesthj-168	9	1	3	3	NUM
anesthj-168	9	2	2022	2022	NUM
anesthj-168	9	3	about	about	ADP
anesthj-168	9	4	the	the	DET
anesthj-168	9	5	author	author	NOUN
anesthj-168	9	6	:	:	PUNCT
anesthj-168	9	7	gage	gage	PROPN
anesthj-168	9	8	walker	walker	PROPN
anesthj-168	9	9	is	be	AUX
anesthj-168	9	10	a	a	DET
anesthj-168	9	11	registered	registered	ADJ
anesthj-168	9	12	nurse	nurse	NOUN
anesthj-168	9	13	pursuing	pursue	VERB
anesthj-168	9	14	his	his	PRON
anesthj-168	9	15	doctorate	doctorate	NOUN
anesthj-168	9	16	in	in	ADP
anesthj-168	9	17	nurse	nurse	PROPN
anesthj-168	9	18	anesthesia	anesthesia	PROPN
anesthj-168	9	19	at	at	ADP
anesthj-168	9	20	texas	texas	PROPN
anesthj-168	9	21	christian	christian	PROPN
anesthj-168	9	22	university	university	PROPN
anesthj-168	9	23	,	,	PUNCT
anesthj-168	9	24	fort	fort	NOUN
anesthj-168	9	25	worth	worth	PROPN
anesthj-168	9	26	,	,	PUNCT
anesthj-168	9	27	texas	texas	PROPN
anesthj-168	9	28	.	.	PUNCT
anesthj-168	10	1	his	his	PRON
anesthj-168	10	2	primary	primary	ADJ
anesthj-168	10	3	clinical	clinical	ADJ
anesthj-168	10	4	site	site	NOUN
anesthj-168	10	5	is	be	AUX
anesthj-168	10	6	in	in	ADP
anesthj-168	10	7	wichita	wichita	PROPN
anesthj-168	10	8	falls	fall	VERB
anesthj-168	10	9	,	,	PUNCT
anesthj-168	10	10	tx	tx	PROPN
anesthj-168	10	11	texas	texas	PROPN
anesthj-168	10	12	christian	christian	PROPN
anesthj-168	10	13	university	university	PROPN
anesthj-168	10	14	“	"	PUNCT
anesthj-168	10	15	the	the	DET
anesthj-168	10	16	science	science	NOUN
anesthj-168	10	17	behind	behind	ADP
anesthj-168	10	18	the	the	DET
anesthj-168	10	19	art	art	NOUN
anesthj-168	10	20	”	"	PUNCT
anesthj-168	10	21	volume	volume	NOUN
anesthj-168	10	22	10	10	NUM
anesthj-168	10	23	no.3	no.3	VERB
anesthj-168	10	24	2022	2022	NUM
anesthj-168	11	1	anesthesia	anesthesia	PROPN
anesthj-168	11	2	ejournal	ejournal	PROPN
anesthj-168	11	3	online	online	PROPN
anesthj-168	11	4	issn	issn	PROPN
anesthj-168	11	5	2333	2333	NUM
anesthj-168	11	6	-	-	SYM
anesthj-168	11	7	2611	2611	NUM
anesthj-168	11	8	page	page	NOUN
anesthj-168	11	9	4	4	NUM
anesthj-168	11	10	powerpoint	powerpoint	NOUN
anesthj-168	11	11	template	template	NOUN
anesthj-168	11	12	©	©	PROPN
anesthj-168	11	13	2009	2009	NUM
anesthj-168	11	14	texas	texas	PROPN
anesthj-168	11	15	christian	christian	PROPN
anesthj-168	11	16	university	university	PROPN
anesthj-168	11	17	,	,	PUNCT
anesthj-168	11	18	center	center	NOUN
anesthj-168	11	19	for	for	ADP
anesthj-168	11	20	instructional	instructional	ADJ
anesthj-168	11	21	services	service	NOUN
anesthj-168	11	22	.	.	PUNCT
anesthj-168	12	1	for	for	ADP
anesthj-168	12	2	educational	educational	ADJ
anesthj-168	12	3	use	use	NOUN
anesthj-168	12	4	only	only	ADV
anesthj-168	12	5	.	.	PUNCT
anesthj-168	13	1	content	content	NOUN
anesthj-168	13	2	is	be	AUX
anesthj-168	13	3	the	the	DET
anesthj-168	13	4	property	property	NOUN
anesthj-168	13	5	of	of	ADP
anesthj-168	13	6	the	the	DET
anesthj-168	13	7	presenter	presenter	NOUN
anesthj-168	13	8	and	and	CCONJ
anesthj-168	13	9	their	their	PRON
anesthj-168	13	10	resources	resource	NOUN
anesthj-168	13	11	.	.	PUNCT
anesthj-168	14	1	introduction	introduction	NOUN
anesthj-168	14	2	•	•	NOUN
anesthj-168	14	3	cardiopulmonary	cardiopulmonary	ADJ
anesthj-168	14	4	bypass	bypass	NOUN
anesthj-168	14	5	grafting	grafting	NOUN
anesthj-168	14	6	(	(	PUNCT
anesthj-168	14	7	cabg	cabg	VERB
anesthj-168	14	8	)	)	PUNCT
anesthj-168	14	9	is	be	AUX
anesthj-168	14	10	the	the	DET
anesthj-168	14	11	most	most	ADV
anesthj-168	14	12	performed	perform	VERB
anesthj-168	14	13	cardiac	cardiac	ADJ
anesthj-168	14	14	procedure	procedure	NOUN
anesthj-168	14	15	done	do	VERB
anesthj-168	14	16	throughout	throughout	ADP
anesthj-168	14	17	the	the	DET
anesthj-168	14	18	world	world	NOUN
anesthj-168	14	19	today1	today1	NOUN
anesthj-168	14	20	•	•	NOUN
anesthj-168	14	21	10.7	10.7	NUM
anesthj-168	14	22	%	%	NOUN
anesthj-168	14	23	of	of	ADP
anesthj-168	14	24	patients	patient	NOUN
anesthj-168	14	25	receiving	receive	VERB
anesthj-168	14	26	protamine	protamine	NOUN
anesthj-168	14	27	experience	experience	NOUN
anesthj-168	14	28	a	a	DET
anesthj-168	14	29	protamine	protamine	NOUN
anesthj-168	14	30	reaction2,3,4	reaction2,3,4	ADJ
anesthj-168	14	31	•	•	NOUN
anesthj-168	14	32	protamine	protamine	NOUN
anesthj-168	14	33	is	be	AUX
anesthj-168	14	34	administered	administer	VERB
anesthj-168	14	35	to	to	PART
anesthj-168	14	36	neutralize	neutralize	VERB
anesthj-168	14	37	the	the	DET
anesthj-168	14	38	anticoagulant	anticoagulant	ADJ
anesthj-168	14	39	effects	effect	NOUN
anesthj-168	14	40	of	of	ADP
anesthj-168	14	41	heparin4	heparin4	NOUN
anesthj-168	14	42	evidence	evidence	NOUN
anesthj-168	14	43	shows	show	VERB
anesthj-168	14	44	that	that	SCONJ
anesthj-168	14	45	when	when	SCONJ
anesthj-168	14	46	a	a	DET
anesthj-168	14	47	reaction	reaction	NOUN
anesthj-168	14	48	does	do	AUX
anesthj-168	14	49	occur	occur	VERB
anesthj-168	14	50	,	,	PUNCT
anesthj-168	14	51	there	there	PRON
anesthj-168	14	52	is	be	VERB
anesthj-168	14	53	an	an	DET
anesthj-168	14	54	increased	increase	VERB
anesthj-168	14	55	mortality	mortality	NOUN
anesthj-168	14	56	risk4	risk4	NOUN
anesthj-168	14	57	•	•	NOUN
anesthj-168	14	58	reactions	reaction	NOUN
anesthj-168	14	59	to	to	ADP
anesthj-168	14	60	protamine	protamine	NOUN
anesthj-168	14	61	can	can	AUX
anesthj-168	14	62	be	be	AUX
anesthj-168	14	63	respiratory	respiratory	ADJ
anesthj-168	14	64	in	in	ADP
anesthj-168	14	65	nature	nature	NOUN
anesthj-168	14	66	such	such	ADJ
anesthj-168	14	67	as	as	ADP
anesthj-168	14	68	wheezing	wheeze	VERB
anesthj-168	14	69	,	,	PUNCT
anesthj-168	14	70	cardiovascular	cardiovascular	ADJ
anesthj-168	14	71	such	such	ADJ
anesthj-168	14	72	as	as	ADP
anesthj-168	14	73	hypotension	hypotension	NOUN
anesthj-168	14	74	,	,	PUNCT
anesthj-168	14	75	impaired	impaired	ADJ
anesthj-168	14	76	cardiac	cardiac	ADJ
anesthj-168	14	77	output	output	NOUN
anesthj-168	14	78	,	,	PUNCT
anesthj-168	14	79	arrhythmias	arrhythmia	NOUN
anesthj-168	14	80	,	,	PUNCT
anesthj-168	14	81	pulmonary	pulmonary	ADJ
anesthj-168	14	82	hypertension	hypertension	NOUN
anesthj-168	14	83	,	,	PUNCT
anesthj-168	14	84	or	or	CCONJ
anesthj-168	14	85	cardiac	cardiac	ADJ
anesthj-168	14	86	arrest	arrest	NOUN
anesthj-168	14	87	,	,	PUNCT
anesthj-168	14	88	skin	skin	NOUN
anesthj-168	14	89	such	such	ADJ
anesthj-168	14	90	as	as	ADP
anesthj-168	14	91	urticaria	urticaria	NOUN
anesthj-168	14	92	,	,	PUNCT
anesthj-168	14	93	flushing	flush	VERB
anesthj-168	14	94	and	and	CCONJ
anesthj-168	14	95	angioedema	angioedema	VERB
anesthj-168	14	96	,	,	PUNCT
anesthj-168	14	97	or	or	CCONJ
anesthj-168	14	98	hematologic	hematologic	NOUN
anesthj-168	14	99	such	such	ADJ
anesthj-168	14	100	as	as	ADP
anesthj-168	14	101	bleeding3	bleeding3	NOUN
anesthj-168	14	102	•	•	NUM
anesthj-168	14	103	protamine	protamine	NOUN
anesthj-168	14	104	is	be	AUX
anesthj-168	14	105	administered	administer	VERB
anesthj-168	14	106	routinely	routinely	ADV
anesthj-168	14	107	in	in	ADP
anesthj-168	14	108	many	many	ADJ
anesthj-168	14	109	vascular	vascular	ADJ
anesthj-168	14	110	procedures	procedure	NOUN
anesthj-168	14	111	therefore	therefore	ADV
anesthj-168	14	112	anesthesia	anesthesia	PROPN
anesthj-168	14	113	providers	provider	NOUN
anesthj-168	14	114	should	should	AUX
anesthj-168	14	115	know	know	VERB
anesthj-168	14	116	the	the	DET
anesthj-168	14	117	risks	risk	NOUN
anesthj-168	14	118	associated	associate	VERB
anesthj-168	14	119	with	with	ADP
anesthj-168	14	120	it	it	PRON
anesthj-168	14	121	and	and	CCONJ
anesthj-168	14	122	what	what	PRON
anesthj-168	14	123	to	to	PART
anesthj-168	14	124	do	do	VERB
anesthj-168	14	125	if	if	SCONJ
anesthj-168	14	126	a	a	DET
anesthj-168	14	127	reaction	reaction	NOUN
anesthj-168	14	128	occurs	occur	VERB
anesthj-168	14	129	•	•	NUM
anesthj-168	14	130	purpose	purpose	NOUN
anesthj-168	14	131	:	:	PUNCT
anesthj-168	14	132	to	to	PART
anesthj-168	14	133	discuss	discuss	VERB
anesthj-168	14	134	known	know	VERB
anesthj-168	14	135	risk	risk	NOUN
anesthj-168	14	136	factors	factor	NOUN
anesthj-168	14	137	that	that	PRON
anesthj-168	14	138	precipitate	precipitate	VERB
anesthj-168	14	139	a	a	DET
anesthj-168	14	140	reaction	reaction	NOUN
anesthj-168	14	141	to	to	ADP
anesthj-168	14	142	protamine	protamine	NOUN
anesthj-168	14	143	,	,	PUNCT
anesthj-168	14	144	how	how	SCONJ
anesthj-168	14	145	often	often	ADV
anesthj-168	14	146	a	a	DET
anesthj-168	14	147	reaction	reaction	NOUN
anesthj-168	14	148	may	may	AUX
anesthj-168	14	149	occur	occur	VERB
anesthj-168	14	150	,	,	PUNCT
anesthj-168	14	151	appropriate	appropriate	ADJ
anesthj-168	14	152	treatment	treatment	NOUN
anesthj-168	14	153	for	for	ADP
anesthj-168	14	154	when	when	SCONJ
anesthj-168	14	155	a	a	DET
anesthj-168	14	156	reaction	reaction	NOUN
anesthj-168	14	157	does	do	AUX
anesthj-168	14	158	occur	occur	VERB
anesthj-168	14	159	,	,	PUNCT
anesthj-168	14	160	and	and	CCONJ
anesthj-168	14	161	if	if	SCONJ
anesthj-168	14	162	there	there	PRON
anesthj-168	14	163	are	be	VERB
anesthj-168	14	164	any	any	DET
anesthj-168	14	165	alternatives	alternative	NOUN
anesthj-168	14	166	to	to	ADP
anesthj-168	14	167	the	the	DET
anesthj-168	14	168	administration	administration	NOUN
anesthj-168	14	169	of	of	ADP
anesthj-168	14	170	protamine	protamine	PROPN
anesthj-168	14	171	available	available	ADJ
anesthj-168	14	172	discussion	discussion	NOUN
anesthj-168	14	173	•	•	NUM
anesthj-168	14	174	studies	study	NOUN
anesthj-168	14	175	show	show	VERB
anesthj-168	14	176	that	that	SCONJ
anesthj-168	14	177	suggested	suggest	VERB
anesthj-168	14	178	treatment	treatment	NOUN
anesthj-168	14	179	is	be	AUX
anesthj-168	14	180	supportive	supportive	ADJ
anesthj-168	14	181	.	.	PUNCT
anesthj-168	15	1	examples	example	NOUN
anesthj-168	15	2	are	be	AUX
anesthj-168	15	3	diphenhydramine	diphenhydramine	ADJ
anesthj-168	15	4	50	50	NUM
anesthj-168	15	5	mg	mg	NOUN
anesthj-168	15	6	iv	iv	NUM
anesthj-168	15	7	to	to	PART
anesthj-168	15	8	treat	treat	VERB
anesthj-168	15	9	cutaneous	cutaneous	ADJ
anesthj-168	15	10	manifestations	manifestation	NOUN
anesthj-168	15	11	,	,	PUNCT
anesthj-168	15	12	large	large	ADJ
anesthj-168	15	13	volumes	volume	NOUN
anesthj-168	15	14	of	of	ADP
anesthj-168	15	15	fluid	fluid	NOUN
anesthj-168	15	16	to	to	PART
anesthj-168	15	17	replace	replace	VERB
anesthj-168	15	18	intravascular	intravascular	ADJ
anesthj-168	15	19	loss	loss	NOUN
anesthj-168	15	20	,	,	PUNCT
anesthj-168	15	21	epinephrine	epinephrine	VERB
anesthj-168	15	22	up	up	ADV
anesthj-168	15	23	to	to	PART
anesthj-168	15	24	4	4	NUM
anesthj-168	15	25	mcg	mcg	NOUN
anesthj-168	15	26	/	/	SYM
anesthj-168	15	27	min	min	NOUN
anesthj-168	15	28	,	,	PUNCT
anesthj-168	15	29	dopamine	dopamine	NOUN
anesthj-168	15	30	5	5	NUM
anesthj-168	15	31	mcg	mcg	NOUN
anesthj-168	15	32	/	/	SYM
anesthj-168	15	33	kg	kg	PROPN
anesthj-168	15	34	/	/	SYM
anesthj-168	15	35	min	min	PROPN
anesthj-168	15	36	,	,	PUNCT
anesthj-168	15	37	and	and	CCONJ
anesthj-168	15	38	isoproterenol	isoproterenol	NOUN
anesthj-168	15	39	2	2	NUM
anesthj-168	15	40	to	to	PART
anesthj-168	15	41	20	20	NUM
anesthj-168	15	42	mg	mg	NUM
anesthj-168	15	43	/	/	SYM
anesthj-168	15	44	min	min	NOUN
anesthj-168	15	45	to	to	PART
anesthj-168	15	46	support	support	VERB
anesthj-168	15	47	cardiac	cardiac	ADJ
anesthj-168	15	48	function	function	NOUN
anesthj-168	15	49	.	.	PUNCT
anesthj-168	16	1	intra	intra	ADJ
anesthj-168	16	2	-	-	ADJ
anesthj-168	16	3	aortic	aortic	ADJ
anesthj-168	16	4	balloon	balloon	NOUN
anesthj-168	16	5	pump	pump	NOUN
anesthj-168	16	6	has	have	AUX
anesthj-168	16	7	also	also	ADV
anesthj-168	16	8	been	be	AUX
anesthj-168	16	9	utilized	utilize	VERB
anesthj-168	16	10	to	to	PART
anesthj-168	16	11	support	support	VERB
anesthj-168	16	12	cardiac	cardiac	ADJ
anesthj-168	16	13	function2	function2	NOUN
anesthj-168	16	14	•	•	NOUN
anesthj-168	16	15	methylene	methylene	NOUN
anesthj-168	16	16	blue	blue	NOUN
anesthj-168	16	17	(	(	PUNCT
anesthj-168	16	18	500	500	NUM
anesthj-168	16	19	mg	mg	NOUN
anesthj-168	16	20	)	)	PUNCT
anesthj-168	16	21	has	have	AUX
anesthj-168	16	22	successfully	successfully	ADV
anesthj-168	16	23	treated	treat	VERB
anesthj-168	16	24	sustained	sustained	ADJ
anesthj-168	16	25	hypotension	hypotension	NOUN
anesthj-168	16	26	after	after	SCONJ
anesthj-168	16	27	traditional	traditional	ADJ
anesthj-168	16	28	supportive	supportive	ADJ
anesthj-168	16	29	measures	measure	NOUN
anesthj-168	16	30	were	be	AUX
anesthj-168	16	31	unsuccessful5	unsuccessful5	ADJ
anesthj-168	16	32	•	•	ADP
anesthj-168	16	33	a	a	DET
anesthj-168	16	34	fixed	fixed	ADJ
anesthj-168	16	35	protamine	protamine	NOUN
anesthj-168	16	36	:	:	PUNCT
anesthj-168	16	37	heparin	heparin	ADJ
anesthj-168	16	38	ratio	ratio	NOUN
anesthj-168	16	39	dose	dose	NOUN
anesthj-168	16	40	may	may	AUX
anesthj-168	16	41	be	be	AUX
anesthj-168	16	42	overdosing	overdose	VERB
anesthj-168	16	43	or	or	CCONJ
anesthj-168	16	44	underdosing	underdose	VERB
anesthj-168	16	45	the	the	DET
anesthj-168	16	46	protamine	protamine	NOUN
anesthj-168	16	47	leading	lead	VERB
anesthj-168	16	48	to	to	ADP
anesthj-168	16	49	adverse	adverse	ADJ
anesthj-168	16	50	outcomes6	outcomes6	NOUN
anesthj-168	16	51	•	•	ADP
anesthj-168	16	52	a	a	DET
anesthj-168	16	53	heparin	heparin	ADJ
anesthj-168	16	54	removal	removal	NOUN
anesthj-168	16	55	device	device	NOUN
anesthj-168	16	56	which	which	PRON
anesthj-168	16	57	is	be	AUX
anesthj-168	16	58	an	an	DET
anesthj-168	16	59	extracorporeal	extracorporeal	NOUN
anesthj-168	16	60	plasmapheresis	plasmapheresis	NOUN
anesthj-168	16	61	filter	filter	NOUN
anesthj-168	16	62	that	that	PRON
anesthj-168	16	63	contains	contain	VERB
anesthj-168	16	64	a	a	DET
anesthj-168	16	65	resin	resin	NOUN
anesthj-168	16	66	which	which	PRON
anesthj-168	16	67	binds	bind	VERB
anesthj-168	16	68	and	and	CCONJ
anesthj-168	16	69	immobilizes	immobilize	VERB
anesthj-168	16	70	heparin	heparin	ADV
anesthj-168	16	71	from	from	ADP
anesthj-168	16	72	circulating	circulate	VERB
anesthj-168	16	73	heparinized	heparinize	VERB
anesthj-168	16	74	blood	blood	NOUN
anesthj-168	16	75	,	,	PUNCT
anesthj-168	16	76	was	be	AUX
anesthj-168	16	77	utilized	utilize	VERB
anesthj-168	16	78	after	after	ADP
anesthj-168	16	79	patient	patient	NOUN
anesthj-168	16	80	suffered	suffer	VERB
anesthj-168	16	81	a	a	DET
anesthj-168	16	82	reaction	reaction	NOUN
anesthj-168	16	83	from	from	ADP
anesthj-168	16	84	protamine	protamine	NOUN
anesthj-168	16	85	and	and	CCONJ
anesthj-168	16	86	was	be	AUX
anesthj-168	16	87	still	still	ADV
anesthj-168	16	88	bleeding	bleed	VERB
anesthj-168	16	89	after	after	ADP
anesthj-168	16	90	wound	wound	NOUN
anesthj-168	16	91	closure	closure	NOUN
anesthj-168	16	92	.	.	PUNCT
anesthj-168	17	1	patient	patient	NOUN
anesthj-168	17	2	was	be	AUX
anesthj-168	17	3	brought	bring	VERB
anesthj-168	17	4	back	back	ADV
anesthj-168	17	5	to	to	ADP
anesthj-168	17	6	or	or	CCONJ
anesthj-168	17	7	and	and	CCONJ
anesthj-168	17	8	hrd	hrd	NOUN
anesthj-168	17	9	was	be	AUX
anesthj-168	17	10	able	able	ADJ
anesthj-168	17	11	to	to	PART
anesthj-168	17	12	bring	bring	VERB
anesthj-168	17	13	act	act	NOUN
anesthj-168	17	14	to	to	ADP
anesthj-168	17	15	160	160	NUM
anesthj-168	17	16	seconds	second	NOUN
anesthj-168	17	17	which	which	PRON
anesthj-168	17	18	was	be	AUX
anesthj-168	17	19	below	below	ADP
anesthj-168	17	20	the	the	DET
anesthj-168	17	21	baseline	baseline	NOUN
anesthj-168	17	22	of	of	ADP
anesthj-168	17	23	192	192	NUM
anesthj-168	17	24	seconds	second	NOUN
anesthj-168	17	25	after	after	ADP
anesthj-168	17	26	a	a	DET
anesthj-168	17	27	25	25	NUM
anesthj-168	17	28	-	-	PUNCT
anesthj-168	17	29	minute	minute	NOUN
anesthj-168	17	30	run	run	NOUN
anesthj-168	17	31	time7	time7	NOUN
anesthj-168	17	32	•	•	ADP
anesthj-168	17	33	a	a	DET
anesthj-168	17	34	bovine	bovine	NOUN
anesthj-168	17	35	study	study	NOUN
anesthj-168	17	36	demonstrated	demonstrate	VERB
anesthj-168	17	37	hrd	hrd	PROPN
anesthj-168	17	38	was	be	AUX
anesthj-168	17	39	able	able	ADJ
anesthj-168	17	40	to	to	PART
anesthj-168	17	41	reverse	reverse	VERB
anesthj-168	17	42	heparin	heparin	ADV
anesthj-168	17	43	equal	equal	ADJ
anesthj-168	17	44	to	to	ADP
anesthj-168	17	45	protamine	protamine	VERB
anesthj-168	17	46	in	in	ADP
anesthj-168	17	47	an	an	DET
anesthj-168	17	48	average	average	NOUN
anesthj-168	17	49	of	of	ADP
anesthj-168	17	50	31	31	NUM
anesthj-168	17	51	minutes	minute	NOUN
anesthj-168	17	52	compared	compare	VERB
anesthj-168	17	53	to	to	ADP
anesthj-168	17	54	a	a	DET
anesthj-168	17	55	standard	standard	ADJ
anesthj-168	17	56	15	15	NUM
anesthj-168	17	57	-	-	PUNCT
anesthj-168	17	58	minute	minute	NOUN
anesthj-168	17	59	infusion8	infusion8	NOUN
anesthj-168	17	60	case	case	NOUN
anesthj-168	17	61	critique	critique	VERB
anesthj-168	17	62	•	•	NOUN
anesthj-168	17	63	utilizing	utilize	VERB
anesthj-168	17	64	a	a	DET
anesthj-168	17	65	fixed	fixed	ADJ
anesthj-168	17	66	protamine	protamine	NOUN
anesthj-168	17	67	:	:	PUNCT
anesthj-168	17	68	heparin	heparin	ADJ
anesthj-168	17	69	ratio	ratio	NOUN
anesthj-168	17	70	overdosing	overdose	VERB
anesthj-168	17	71	the	the	DET
anesthj-168	17	72	protamine	protamine	NOUN
anesthj-168	17	73	could	could	AUX
anesthj-168	17	74	have	have	AUX
anesthj-168	17	75	led	lead	VERB
anesthj-168	17	76	to	to	ADP
anesthj-168	17	77	the	the	DET
anesthj-168	17	78	reaction6	reaction6	NOUN
anesthj-168	17	79	•	•	ADP
anesthj-168	17	80	the	the	DET
anesthj-168	17	81	use	use	NOUN
anesthj-168	17	82	of	of	ADP
anesthj-168	17	83	methylene	methylene	ADJ
anesthj-168	17	84	blue	blue	NOUN
anesthj-168	17	85	was	be	AUX
anesthj-168	17	86	a	a	DET
anesthj-168	17	87	positive	positive	NOUN
anesthj-168	17	88	,	,	PUNCT
anesthj-168	17	89	but	but	CCONJ
anesthj-168	17	90	it	it	PRON
anesthj-168	17	91	could	could	AUX
anesthj-168	17	92	have	have	AUX
anesthj-168	17	93	possibly	possibly	ADV
anesthj-168	17	94	been	be	AUX
anesthj-168	17	95	administered	administer	VERB
anesthj-168	17	96	sooner	soon	ADV
anesthj-168	17	97	•	•	ADP
anesthj-168	17	98	a	a	DET
anesthj-168	17	99	heparin	heparin	ADJ
anesthj-168	17	100	removal	removal	NOUN
anesthj-168	17	101	device	device	NOUN
anesthj-168	17	102	could	could	AUX
anesthj-168	17	103	have	have	AUX
anesthj-168	17	104	been	be	AUX
anesthj-168	17	105	utilized	utilize	VERB
anesthj-168	17	106	to	to	PART
anesthj-168	17	107	reverse	reverse	VERB
anesthj-168	17	108	the	the	DET
anesthj-168	17	109	heparin	heparin	NOUN
anesthj-168	17	110	lowering	lower	VERB
anesthj-168	17	111	the	the	DET
anesthj-168	17	112	amount	amount	NOUN
anesthj-168	17	113	of	of	ADP
anesthj-168	17	114	time	time	NOUN
anesthj-168	17	115	the	the	DET
anesthj-168	17	116	patient	patient	NOUN
anesthj-168	17	117	required	require	VERB
anesthj-168	17	118	cardiopulmonary	cardiopulmonary	ADJ
anesthj-168	17	119	bypass	bypass	NOUN
anesthj-168	17	120	but	but	CCONJ
anesthj-168	17	121	as	as	ADP
anesthj-168	17	122	of	of	ADP
anesthj-168	17	123	now	now	ADV
anesthj-168	17	124	it	it	PRON
anesthj-168	17	125	has	have	AUX
anesthj-168	17	126	not	not	PART
anesthj-168	17	127	received	receive	VERB
anesthj-168	17	128	fda	fda	PROPN
anesthj-168	17	129	approval7	approval7	PROPN
anesthj-168	17	130	•	•	NUM
anesthj-168	17	131	appropriate	appropriate	ADJ
anesthj-168	17	132	utilization	utilization	NOUN
anesthj-168	17	133	of	of	ADP
anesthj-168	17	134	vasopressors	vasopressor	NOUN
anesthj-168	17	135	and	and	CCONJ
anesthj-168	17	136	intra	intra	ADJ
anesthj-168	17	137	-	-	ADJ
anesthj-168	17	138	aortic	aortic	ADJ
anesthj-168	17	139	balloon	balloon	NOUN
anesthj-168	17	140	pump	pump	NOUN
anesthj-168	17	141	to	to	PART
anesthj-168	17	142	support	support	VERB
anesthj-168	17	143	cardiac	cardiac	ADJ
anesthj-168	17	144	function2	function2	NOUN
anesthj-168	17	145	•	•	NOUN
anesthj-168	17	146	protamine	protamine	NOUN
anesthj-168	17	147	was	be	AUX
anesthj-168	17	148	administered	administer	VERB
anesthj-168	17	149	via	via	ADP
anesthj-168	17	150	micro	micro	ADJ
anesthj-168	17	151	drip	drip	NOUN
anesthj-168	17	152	over	over	ADP
anesthj-168	17	153	15	15	NUM
anesthj-168	17	154	minutes	minute	NOUN
anesthj-168	17	155	which	which	PRON
anesthj-168	17	156	aligns	align	VERB
anesthj-168	17	157	with	with	ADP
anesthj-168	17	158	research2	research2	PROPN
anesthj-168	17	159	protamine	protamine	PROPN
anesthj-168	17	160	reaction	reaction	NOUN
anesthj-168	17	161	in	in	ADP
anesthj-168	17	162	cardiovascular	cardiovascular	ADJ
anesthj-168	17	163	surgery	surgery	NOUN
anesthj-168	17	164	gage	gage	NOUN
anesthj-168	17	165	walker	walker	PROPN
anesthj-168	17	166	,	,	PUNCT
anesthj-168	17	167	bsn	bsn	PROPN
anesthj-168	17	168	,	,	PUNCT
anesthj-168	17	169	rn	rn	PROPN
anesthj-168	17	170	,	,	PUNCT
anesthj-168	17	171	texas	texas	PROPN
anesthj-168	17	172	christian	christian	PROPN
anesthj-168	17	173	university	university	PROPN
anesthj-168	17	174	figure	figure	NOUN
anesthj-168	17	175	1	1	NUM
anesthj-168	17	176	.	.	PUNCT
anesthj-168	18	1	demonstration	demonstration	NOUN
anesthj-168	18	2	of	of	ADP
anesthj-168	18	3	protamine	protamine	NOUN
anesthj-168	18	4	pathophysiology	pathophysiology	NOUN
anesthj-168	18	5	causing	cause	VERB
anesthj-168	18	6	hypotension9	hypotension9	NOUN
anesthj-168	18	7	case	case	NOUN
anesthj-168	18	8	summary	summary	VERB
anesthj-168	18	9	•	•	NUM
anesthj-168	18	10	80	80	NUM
anesthj-168	18	11	-	-	PUNCT
anesthj-168	18	12	year	year	NOUN
anesthj-168	18	13	-	-	PUNCT
anesthj-168	18	14	old	old	ADJ
anesthj-168	18	15	female	female	NOUN
anesthj-168	18	16	,	,	PUNCT
anesthj-168	18	17	165	165	NUM
anesthj-168	18	18	cm	cm	NOUN
anesthj-168	18	19	,	,	PUNCT
anesthj-168	18	20	77	77	NUM
anesthj-168	18	21	kg	kg	NOUN
anesthj-168	18	22	,	,	PUNCT
anesthj-168	18	23	scheduled	schedule	VERB
anesthj-168	18	24	for	for	ADP
anesthj-168	18	25	elective	elective	ADJ
anesthj-168	18	26	cabg	cabg	ADJ
anesthj-168	18	27	anesthetic	anesthetic	ADJ
anesthj-168	18	28	evaluation	evaluation	NOUN
anesthj-168	18	29	•	•	NOUN
anesthj-168	18	30	pmh	pmh	NOUN
anesthj-168	18	31	:	:	PUNCT
anesthj-168	18	32	cad	cad	PROPN
anesthj-168	18	33	,	,	PUNCT
anesthj-168	18	34	htn	htn	PROPN
anesthj-168	18	35	,	,	PUNCT
anesthj-168	18	36	mi	mi	PROPN
anesthj-168	18	37	with	with	ADP
anesthj-168	18	38	stent	stent	NOUN
anesthj-168	18	39	,	,	PUNCT
anesthj-168	18	40	ppm	ppm	ADJ
anesthj-168	18	41	due	due	ADP
anesthj-168	18	42	to	to	ADP
anesthj-168	18	43	heart	heart	NOUN
anesthj-168	18	44	block	block	NOUN
anesthj-168	18	45	,	,	PUNCT
anesthj-168	18	46	gerd	gerd	NOUN
anesthj-168	18	47	,	,	PUNCT
anesthj-168	18	48	hypothyroid	hypothyroid	ADJ
anesthj-168	18	49	,	,	PUNCT
anesthj-168	18	50	ddd	ddd	PROPN
anesthj-168	18	51	,	,	PUNCT
anesthj-168	18	52	parkinson	parkinson	NOUN
anesthj-168	18	53	’s	’s	PART
anesthj-168	18	54	disease	disease	NOUN
anesthj-168	18	55	•	•	NOUN
anesthj-168	18	56	labs	lab	NOUN
anesthj-168	18	57	:	:	PUNCT
anesthj-168	18	58	na-139	na-139	NOUN
anesthj-168	18	59	,	,	PUNCT
anesthj-168	18	60	k-4.6	k-4.6	NOUN
anesthj-168	18	61	,	,	PUNCT
anesthj-168	18	62	cl-105	cl-105	NOUN
anesthj-168	18	63	,	,	PUNCT
anesthj-168	18	64	co2	co2	NOUN
anesthj-168	18	65	-	-	PUNCT
anesthj-168	18	66	28	28	NUM
anesthj-168	18	67	,	,	PUNCT
anesthj-168	18	68	gap-11	gap-11	NOUN
anesthj-168	18	69	,	,	PUNCT
anesthj-168	18	70	bun-30	bun-30	NOUN
anesthj-168	18	71	,	,	PUNCT
anesthj-168	18	72	crea-0.93	crea-0.93	PROPN
anesthj-168	18	73	,	,	PUNCT
anesthj-168	18	74	egfr-58	egfr-58	PROPN
anesthj-168	18	75	,	,	PUNCT
anesthj-168	18	76	glucose-132	glucose-132	NOUN
anesthj-168	18	77	,	,	PUNCT
anesthj-168	18	78	calcium-9.8	calcium-9.8	PROPN
anesthj-168	18	79	,	,	PUNCT
anesthj-168	18	80	alk	alk	VERB
anesthj-168	18	81	phos-78	phos-78	PROPN
anesthj-168	18	82	,	,	PUNCT
anesthj-168	18	83	albumin-3.8	albumin-3.8	PRON
anesthj-168	18	84	,	,	PUNCT
anesthj-168	18	85	wbc-4.7	wbc-4.7	NOUN
anesthj-168	18	86	,	,	PUNCT
anesthj-168	18	87	rbc-4.03	rbc-4.03	ADJ
anesthj-168	18	88	,	,	PUNCT
anesthj-168	18	89	hgb-11.1	hgb-11.1	PROPN
anesthj-168	18	90	,	,	PUNCT
anesthj-168	18	91	hct-35.3	hct-35.3	PROPN
anesthj-168	18	92	,	,	PUNCT
anesthj-168	18	93	plt-267	plt-267	ADJ
anesthj-168	18	94	•	•	NUM
anesthj-168	18	95	echo	echo	NOUN
anesthj-168	18	96	:	:	PUNCT
anesthj-168	18	97	ef	ef	PROPN
anesthj-168	18	98	45	45	NUM
anesthj-168	18	99	%	%	NOUN
anesthj-168	18	100	,	,	PUNCT
anesthj-168	18	101	moderate	moderate	ADJ
anesthj-168	18	102	mitral	mitral	ADJ
anesthj-168	18	103	regurgitation	regurgitation	NOUN
anesthj-168	18	104	,	,	PUNCT
anesthj-168	18	105	moderate	moderate	ADJ
anesthj-168	18	106	pulmonary	pulmonary	ADJ
anesthj-168	18	107	hypertension	hypertension	NOUN
anesthj-168	18	108	•	•	ADP
anesthj-168	18	109	angiography	angiography	NOUN
anesthj-168	18	110	:	:	PUNCT
anesthj-168	18	111	left	leave	VERB
anesthj-168	18	112	main	main	ADJ
anesthj-168	18	113	70	70	NUM
anesthj-168	18	114	-	-	SYM
anesthj-168	18	115	80	80	NUM
anesthj-168	18	116	%	%	NOUN
anesthj-168	18	117	stenosis	stenosis	NOUN
anesthj-168	18	118	,	,	PUNCT
anesthj-168	18	119	rca	rca	PROPN
anesthj-168	18	120	80	80	NUM
anesthj-168	18	121	%	%	NOUN
anesthj-168	18	122	stenosis	stenosis	NOUN
anesthj-168	18	123	,	,	PUNCT
anesthj-168	18	124	lad	lad	NOUN
anesthj-168	18	125	80	80	NUM
anesthj-168	18	126	-	-	SYM
anesthj-168	18	127	90	90	NUM
anesthj-168	18	128	%	%	NOUN
anesthj-168	18	129	stenosis	stenosis	NOUN
anesthj-168	18	130	•	•	NOUN
anesthj-168	18	131	medications	medication	NOUN
anesthj-168	18	132	:	:	PUNCT
anesthj-168	18	133	aspirin	aspirin	NOUN
anesthj-168	18	134	,	,	PUNCT
anesthj-168	18	135	omeprazole	omeprazole	NOUN
anesthj-168	18	136	,	,	PUNCT
anesthj-168	18	137	potassium	potassium	NOUN
anesthj-168	18	138	chloride	chloride	NOUN
anesthj-168	18	139	,	,	PUNCT
anesthj-168	18	140	levetiracetam	levetiracetam	NOUN
anesthj-168	18	141	,	,	PUNCT
anesthj-168	18	142	escitalopram	escitalopram	PROPN
anesthj-168	18	143	,	,	PUNCT
anesthj-168	18	144	levothyroxine	levothyroxine	PROPN
anesthj-168	18	145	,	,	PUNCT
anesthj-168	18	146	metoprolol	metoprolol	NOUN
anesthj-168	18	147	,	,	PUNCT
anesthj-168	18	148	calcium	calcium	NOUN
anesthj-168	18	149	carbonate	carbonate	NOUN
anesthj-168	18	150	,	,	PUNCT
anesthj-168	18	151	carbidopa	carbidopa	NOUN
anesthj-168	18	152	/	/	SYM
anesthj-168	18	153	levodopa	levodopa	NOUN
anesthj-168	18	154	,	,	PUNCT
anesthj-168	18	155	acetaminophen	acetaminophen	NOUN
anesthj-168	18	156	,	,	PUNCT
anesthj-168	18	157	atorvastatin	atorvastatin	PROPN
anesthj-168	18	158	•	•	ADP
anesthj-168	18	159	psh	psh	PROPN
anesthj-168	18	160	:	:	PUNCT
anesthj-168	18	161	cardiac	cardiac	ADJ
anesthj-168	18	162	stent	stent	NOUN
anesthj-168	18	163	placement	placement	NOUN
anesthj-168	18	164	,	,	PUNCT
anesthj-168	18	165	hysterectomy	hysterectomy	NOUN
anesthj-168	18	166	•	•	NOUN
anesthj-168	18	167	premedication	premedication	NOUN
anesthj-168	18	168	:	:	PUNCT
anesthj-168	19	1	none	none	NOUN
anesthj-168	19	2	•	•	NUM
anesthj-168	19	3	anesthetic	anesthetic	ADJ
anesthj-168	19	4	plan	plan	NOUN
anesthj-168	19	5	:	:	PUNCT
anesthj-168	19	6	geta	geta	NOUN
anesthj-168	19	7	,	,	PUNCT
anesthj-168	19	8	a	a	DET
anesthj-168	19	9	-	-	PUNCT
anesthj-168	19	10	line	line	NOUN
anesthj-168	19	11	and	and	CCONJ
anesthj-168	19	12	cvl	cvl	VERB
anesthj-168	19	13	post	post	ADJ
anesthj-168	19	14	-	-	ADJ
anesthj-168	19	15	induction	induction	ADJ
anesthj-168	19	16	intraoperative	intraoperative	ADJ
anesthj-168	19	17	course	course	NOUN
anesthj-168	19	18	•	•	NUM
anesthj-168	19	19	monitors	monitor	NOUN
anesthj-168	19	20	applied	apply	VERB
anesthj-168	19	21	,	,	PUNCT
anesthj-168	19	22	preoxygenation	preoxygenation	NOUN
anesthj-168	19	23	•	•	NOUN
anesthj-168	19	24	induction	induction	NOUN
anesthj-168	19	25	:	:	PUNCT
anesthj-168	19	26	60	60	NUM
anesthj-168	19	27	mg	mg	NOUN
anesthj-168	19	28	propofol	propofol	NOUN
anesthj-168	19	29	,	,	PUNCT
anesthj-168	19	30	5	5	NUM
anesthj-168	19	31	mcg	mcg	NOUN
anesthj-168	19	32	sufentanil	sufentanil	NOUN
anesthj-168	19	33	,	,	PUNCT
anesthj-168	19	34	50	50	NUM
anesthj-168	19	35	mg	mg	PROPN
anesthj-168	19	36	lidocaine	lidocaine	NOUN
anesthj-168	19	37	,	,	PUNCT
anesthj-168	19	38	30	30	NUM
anesthj-168	19	39	mg	mg	PROPN
anesthj-168	19	40	rocuronium	rocuronium	NOUN
anesthj-168	19	41	for	for	ADP
anesthj-168	19	42	muscle	muscle	NOUN
anesthj-168	19	43	relaxation	relaxation	NOUN
anesthj-168	19	44	•	•	NOUN
anesthj-168	19	45	intubation	intubation	NOUN
anesthj-168	19	46	:	:	PUNCT
anesthj-168	20	1	dl	dl	PROPN
anesthj-168	20	2	x	x	SYM
anesthj-168	20	3	1	1	NUM
anesthj-168	20	4	,	,	PUNCT
anesthj-168	20	5	grade	grade	NOUN
anesthj-168	20	6	i	i	PRON
anesthj-168	20	7	view	view	VERB
anesthj-168	20	8	,	,	PUNCT
anesthj-168	20	9	ett	ett	PROPN
anesthj-168	20	10	8.0	8.0	NUM
anesthj-168	20	11	•	•	PROPN
anesthj-168	20	12	maintenance	maintenance	NOUN
anesthj-168	20	13	:	:	PUNCT
anesthj-168	21	1	sevoflurane	sevoflurane	PROPN
anesthj-168	21	2	titrated	titrate	VERB
anesthj-168	21	3	to	to	PART
anesthj-168	21	4	effect	effect	VERB
anesthj-168	21	5	,	,	PUNCT
anesthj-168	21	6	ivp	ivp	NOUN
anesthj-168	21	7	sufentanil	sufentanil	NOUN
anesthj-168	21	8	,	,	PUNCT
anesthj-168	21	9	vecuronium	vecuronium	NOUN
anesthj-168	21	10	for	for	ADP
anesthj-168	21	11	muscle	muscle	NOUN
anesthj-168	21	12	relaxation	relaxation	NOUN
anesthj-168	21	13	•	•	ADP
anesthj-168	21	14	emergence	emergence	NOUN
anesthj-168	21	15	:	:	PUNCT
anesthj-168	21	16	postoperative	postoperative	ADJ
anesthj-168	21	17	ventilatory	ventilatory	ADJ
anesthj-168	21	18	support	support	NOUN
anesthj-168	21	19	,	,	PUNCT
anesthj-168	21	20	dexmedetomidine	dexmedetomidine	NOUN
anesthj-168	21	21	infusion	infusion	NOUN
anesthj-168	21	22	@	@	ADP
anesthj-168	21	23	0.5	0.5	NUM
anesthj-168	21	24	mcg	mcg	PROPN
anesthj-168	21	25	/	/	SYM
anesthj-168	21	26	kg	kg	PROPN
anesthj-168	21	27	/	/	SYM
anesthj-168	21	28	hr	hr	NOUN
anesthj-168	21	29	•	•	NOUN
anesthj-168	21	30	severe	severe	ADJ
anesthj-168	21	31	reaction	reaction	NOUN
anesthj-168	21	32	after	after	ADP
anesthj-168	21	33	administration	administration	NOUN
anesthj-168	21	34	of	of	ADP
anesthj-168	21	35	protamine	protamine	PROPN
anesthj-168	21	36	with	with	ADP
anesthj-168	21	37	bp	bp	PROPN
anesthj-168	21	38	dropping	drop	VERB
anesthj-168	21	39	as	as	ADV
anesthj-168	21	40	low	low	ADJ
anesthj-168	21	41	as	as	ADP
anesthj-168	21	42	32/17	32/17	NUM
anesthj-168	21	43	mmhg	mmhg	NOUN
anesthj-168	21	44	•	•	NUM
anesthj-168	21	45	treated	treat	VERB
anesthj-168	21	46	with	with	ADP
anesthj-168	21	47	norepinephrine	norepinephrine	NOUN
anesthj-168	21	48	,	,	PUNCT
anesthj-168	21	49	epinephrine	epinephrine	NOUN
anesthj-168	21	50	,	,	PUNCT
anesthj-168	21	51	vasopressin	vasopressin	NOUN
anesthj-168	21	52	and	and	CCONJ
anesthj-168	21	53	calcium	calcium	NOUN
anesthj-168	21	54	chloride	chloride	NOUN
anesthj-168	21	55	•	•	NOUN
anesthj-168	21	56	methylene	methylene	NOUN
anesthj-168	21	57	blue	blue	NOUN
anesthj-168	21	58	was	be	AUX
anesthj-168	21	59	administered	administer	VERB
anesthj-168	21	60	,	,	PUNCT
anesthj-168	21	61	and	and	CCONJ
anesthj-168	21	62	the	the	DET
anesthj-168	21	63	patient	patient	NOUN
anesthj-168	21	64	was	be	AUX
anesthj-168	21	65	placed	place	VERB
anesthj-168	21	66	on	on	ADP
anesthj-168	21	67	an	an	DET
anesthj-168	21	68	iabp	iabp	NOUN
anesthj-168	21	69	•	•	NOUN
anesthj-168	21	70	decision	decision	NOUN
anesthj-168	21	71	:	:	PUNCT
anesthj-168	21	72	to	to	PART
anesthj-168	21	73	heparinize	heparinize	VERB
anesthj-168	21	74	again	again	ADV
anesthj-168	21	75	and	and	CCONJ
anesthj-168	21	76	place	place	VERB
anesthj-168	21	77	the	the	DET
anesthj-168	21	78	patient	patient	NOUN
anesthj-168	21	79	back	back	ADV
anesthj-168	21	80	on	on	ADP
anesthj-168	21	81	cpb	cpb	PROPN
anesthj-168	21	82	•	•	ADP
anesthj-168	21	83	once	once	ADV
anesthj-168	21	84	act	act	NOUN
anesthj-168	21	85	was	be	AUX
anesthj-168	21	86	175	175	NUM
anesthj-168	21	87	seconds	second	NOUN
anesthj-168	21	88	,	,	PUNCT
anesthj-168	21	89	patient	patient	NOUN
anesthj-168	21	90	was	be	AUX
anesthj-168	21	91	closed	close	VERB
anesthj-168	21	92	and	and	CCONJ
anesthj-168	21	93	taken	take	VERB
anesthj-168	21	94	to	to	ADP
anesthj-168	21	95	the	the	DET
anesthj-168	21	96	icu	icu	PROPN
anesthj-168	21	97	on	on	ADP
anesthj-168	21	98	iabp	iabp	NOUN
anesthj-168	21	99	postoperative	postoperative	ADJ
anesthj-168	21	100	course	course	NOUN
anesthj-168	21	101	•	•	NUM
anesthj-168	21	102	iabp	iabp	NOUN
anesthj-168	21	103	was	be	AUX
anesthj-168	21	104	discontinued	discontinue	VERB
anesthj-168	21	105	on	on	ADP
anesthj-168	21	106	pod	pod	PROPN
anesthj-168	21	107	2	2	NUM
anesthj-168	21	108	.	.	NUM
anesthj-168	21	109	extubated	extubate	VERB
anesthj-168	21	110	pod	pod	NOUN
anesthj-168	21	111	3	3	NUM
anesthj-168	21	112	.	.	PUNCT
anesthj-168	21	113	oxygen	oxygen	NOUN
anesthj-168	21	114	requirements	requirement	NOUN
anesthj-168	21	115	began	begin	VERB
anesthj-168	21	116	increasing	increase	VERB
anesthj-168	21	117	on	on	ADP
anesthj-168	21	118	pod	pod	NOUN
anesthj-168	21	119	8	8	NUM
anesthj-168	21	120	which	which	PRON
anesthj-168	21	121	required	require	VERB
anesthj-168	21	122	bipap	bipap	PROPN
anesthj-168	21	123	.	.	PUNCT
anesthj-168	22	1	reintubated	reintubate	VERB
anesthj-168	22	2	and	and	CCONJ
anesthj-168	22	3	eventually	eventually	ADV
anesthj-168	22	4	suffered	suffer	VERB
anesthj-168	22	5	cardiac	cardiac	ADJ
anesthj-168	22	6	arrest	arrest	NOUN
anesthj-168	22	7	with	with	ADP
anesthj-168	22	8	cpr	cpr	PROPN
anesthj-168	22	9	initiated	initiate	VERB
anesthj-168	22	10	and	and	CCONJ
anesthj-168	22	11	rosc	rosc	ADJ
anesthj-168	22	12	on	on	ADP
anesthj-168	22	13	pod	pod	NOUN
anesthj-168	22	14	9	9	NUM
anesthj-168	22	15	.	.	PUNCT
anesthj-168	22	16	comfort	comfort	NOUN
anesthj-168	22	17	measures	measure	NOUN
anesthj-168	22	18	were	be	AUX
anesthj-168	22	19	later	later	ADV
anesthj-168	22	20	initiated	initiate	VERB
anesthj-168	22	21	,	,	PUNCT
anesthj-168	22	22	and	and	CCONJ
anesthj-168	22	23	patient	patient	NOUN
anesthj-168	22	24	passed	pass	VERB
anesthj-168	22	25	on	on	ADP
anesthj-168	22	26	pod	pod	PROPN
anesthj-168	22	27	9	9	NUM
anesthj-168	22	28	.	.	PUNCT
anesthj-168	22	29	references	reference	NOUN
anesthj-168	22	30	1	1	NUM
anesthj-168	22	31	.	.	PUNCT
anesthj-168	23	1	roger	roger	PROPN
anesthj-168	23	2	vl	vl	PROPN
anesthj-168	23	3	,	,	PUNCT
anesthj-168	23	4	go	go	VERB
anesthj-168	23	5	as	as	ADP
anesthj-168	23	6	,	,	PUNCT
anesthj-168	23	7	lloyd	lloyd	PROPN
anesthj-168	23	8	-	-	PUNCT
anesthj-168	23	9	jones	jones	PROPN
anesthj-168	23	10	dm	dm	PROPN
anesthj-168	23	11	,	,	PUNCT
anesthj-168	23	12	et	et	PROPN
anesthj-168	23	13	al	al	PROPN
anesthj-168	23	14	.	.	PUNCT
anesthj-168	23	15	heart	heart	NOUN
anesthj-168	23	16	disease	disease	NOUN
anesthj-168	23	17	and	and	CCONJ
anesthj-168	23	18	stroke	stroke	NOUN
anesthj-168	23	19	statistics--2012	statistics--2012	NOUN
anesthj-168	23	20	update	update	NOUN
anesthj-168	23	21	:	:	PUNCT
anesthj-168	23	22	a	a	DET
anesthj-168	23	23	report	report	NOUN
anesthj-168	23	24	from	from	ADP
anesthj-168	23	25	the	the	DET
anesthj-168	23	26	american	american	ADJ
anesthj-168	23	27	heart	heart	PROPN
anesthj-168	23	28	association	association	PROPN
anesthj-168	23	29	[	[	X
anesthj-168	23	30	published	publish	VERB
anesthj-168	23	31	correction	correction	NOUN
anesthj-168	23	32	appears	appear	VERB
anesthj-168	23	33	in	in	ADP
anesthj-168	23	34	circulation	circulation	NOUN
anesthj-168	23	35	.	.	PUNCT
anesthj-168	24	1	2012	2012	NUM
anesthj-168	24	2	jun	jun	PROPN
anesthj-168	24	3	5;125(22):e1002	5;125(22):e1002	NUM
anesthj-168	24	4	]	]	PUNCT
anesthj-168	24	5	.	.	PUNCT
anesthj-168	25	1	circulation	circulation	NOUN
anesthj-168	25	2	.	.	PUNCT
anesthj-168	26	1	2012;125(1):e2	2012;125(1):e2	NUM
anesthj-168	26	2	-	-	PUNCT
anesthj-168	26	3	e220	e220	PROPN
anesthj-168	26	4	.	.	PUNCT
anesthj-168	26	5	doi:10.1161	doi:10.1161	NOUN
anesthj-168	26	6	/	/	SYM
anesthj-168	26	7	cir.0b013e31823ac046	cir.0b013e31823ac046	NOUN
anesthj-168	26	8	2	2	NUM
anesthj-168	26	9	.	.	PUNCT
anesthj-168	27	1	porsche	porsche	PROPN
anesthj-168	27	2	r	r	PROPN
anesthj-168	27	3	,	,	PUNCT
anesthj-168	27	4	brenner	brenner	PROPN
anesthj-168	27	5	zr	zr	PROPN
anesthj-168	27	6	.	.	PROPN
anesthj-168	27	7	allergy	allergy	PROPN
anesthj-168	27	8	to	to	ADP
anesthj-168	27	9	protamine	protamine	PROPN
anesthj-168	27	10	sulfate	sulfate	NOUN
anesthj-168	27	11	.	.	PUNCT
anesthj-168	28	1	heart	heart	NOUN
anesthj-168	28	2	&	&	CCONJ
anesthj-168	28	3	lung	lung	PROPN
anesthj-168	28	4	.	.	PUNCT
anesthj-168	29	1	1999;28(6):418	1999;28(6):418	NUM
anesthj-168	29	2	-	-	SYM
anesthj-168	29	3	428	428	NUM
anesthj-168	29	4	3	3	NUM
anesthj-168	29	5	.	.	PUNCT
anesthj-168	30	1	weiler	weiler	PROPN
anesthj-168	30	2	jm	jm	PROPN
anesthj-168	30	3	,	,	PUNCT
anesthj-168	30	4	gellhaus	gellhaus	PROPN
anesthj-168	30	5	ma	ma	PROPN
anesthj-168	30	6	,	,	PUNCT
anesthj-168	30	7	carter	carter	PROPN
anesthj-168	30	8	jg	jg	PROPN
anesthj-168	30	9	,	,	PUNCT
anesthj-168	30	10	et	et	PROPN
anesthj-168	30	11	al	al	PROPN
anesthj-168	30	12	.	.	PUNCT
anesthj-168	31	1	a	a	DET
anesthj-168	31	2	prospective	prospective	ADJ
anesthj-168	31	3	study	study	NOUN
anesthj-168	31	4	of	of	ADP
anesthj-168	31	5	the	the	DET
anesthj-168	31	6	risk	risk	NOUN
anesthj-168	31	7	of	of	ADP
anesthj-168	31	8	an	an	DET
anesthj-168	31	9	immediate	immediate	ADJ
anesthj-168	31	10	adverse	adverse	ADJ
anesthj-168	31	11	reaction	reaction	NOUN
anesthj-168	31	12	to	to	ADP
anesthj-168	31	13	protamine	protamine	NOUN
anesthj-168	31	14	sulfate	sulfate	NOUN
anesthj-168	31	15	during	during	ADP
anesthj-168	31	16	cardiopulmonary	cardiopulmonary	ADJ
anesthj-168	31	17	bypass	bypass	NOUN
anesthj-168	31	18	surgery	surgery	NOUN
anesthj-168	31	19	.	.	PUNCT
anesthj-168	32	1	j	j	PROPN
anesthj-168	32	2	allergy	allergy	PROPN
anesthj-168	32	3	clin	clin	PROPN
anesthj-168	32	4	immunol	immunol	NOUN
anesthj-168	32	5	.	.	PUNCT
anesthj-168	33	1	1990;85(4):713	1990;85(4):713	NUM
anesthj-168	33	2	-	-	PUNCT
anesthj-168	33	3	719	719	NUM
anesthj-168	33	4	.	.	PUNCT
anesthj-168	34	1	doi:10.1016/0091	doi:10.1016/0091	ADJ
anesthj-168	34	2	-	-	ADJ
anesthj-168	34	3	6749(90)90189	6749(90)90189	NUM
anesthj-168	34	4	-	-	PUNCT
anesthj-168	34	5	b	b	NOUN
anesthj-168	34	6	4	4	NUM
anesthj-168	34	7	.	.	PUNCT
anesthj-168	34	8	nybo	nybo	PROPN
anesthj-168	34	9	m	m	PROPN
anesthj-168	34	10	,	,	PUNCT
anesthj-168	34	11	madsen	madsen	PROPN
anesthj-168	34	12	js	js	PROPN
anesthj-168	34	13	.	.	PUNCT
anesthj-168	35	1	serious	serious	ADJ
anesthj-168	35	2	anaphylactic	anaphylactic	ADJ
anesthj-168	35	3	reactions	reaction	NOUN
anesthj-168	35	4	due	due	ADP
anesthj-168	35	5	to	to	ADP
anesthj-168	35	6	protamine	protamine	NOUN
anesthj-168	35	7	sulfate	sulfate	NOUN
anesthj-168	35	8	:	:	PUNCT
anesthj-168	35	9	a	a	DET
anesthj-168	35	10	systematic	systematic	ADJ
anesthj-168	35	11	literature	literature	NOUN
anesthj-168	35	12	review	review	NOUN
anesthj-168	35	13	.	.	PUNCT
anesthj-168	36	1	basic	basic	ADJ
anesthj-168	36	2	clin	clin	PROPN
anesthj-168	36	3	pharmacol	pharmacol	PROPN
anesthj-168	36	4	toxicol	toxicol	PROPN
anesthj-168	36	5	.	.	PUNCT
anesthj-168	37	1	2008;103(2):192	2008;103(2):192	NUM
anesthj-168	37	2	-	-	SYM
anesthj-168	37	3	196	196	NUM
anesthj-168	37	4	.	.	PUNCT
anesthj-168	38	1	doi:10.1111	doi:10.1111	ADJ
anesthj-168	38	2	/	/	SYM
anesthj-168	38	3	j.1742	j.1742	PROPN
anesthj-168	38	4	-	-	PUNCT
anesthj-168	38	5	7843.2008.00274.x	7843.2008.00274.x	NUM
anesthj-168	38	6	5	5	NUM
anesthj-168	38	7	.	.	PUNCT
anesthj-168	38	8	lutjen	lutjen	PROPN
anesthj-168	38	9	dl	dl	PROPN
anesthj-168	38	10	,	,	PUNCT
anesthj-168	38	11	arndt	arndt	PROPN
anesthj-168	38	12	kl	kl	PROPN
anesthj-168	38	13	.	.	PUNCT
anesthj-168	38	14	methylene	methylene	PROPN
anesthj-168	38	15	blue	blue	PROPN
anesthj-168	38	16	to	to	PART
anesthj-168	38	17	treat	treat	VERB
anesthj-168	38	18	vasoplegia	vasoplegia	NOUN
anesthj-168	38	19	due	due	ADP
anesthj-168	38	20	to	to	ADP
anesthj-168	38	21	a	a	DET
anesthj-168	38	22	severe	severe	ADJ
anesthj-168	38	23	protamine	protamine	NOUN
anesthj-168	38	24	reaction	reaction	NOUN
anesthj-168	38	25	:	:	PUNCT
anesthj-168	38	26	a	a	DET
anesthj-168	38	27	case	case	NOUN
anesthj-168	38	28	report	report	NOUN
anesthj-168	38	29	.	.	PUNCT
anesthj-168	39	1	aana	aana	PROPN
anesthj-168	39	2	j.	j.	PROPN
anesthj-168	39	3	2012;80(3):170	2012;80(3):170	PROPN
anesthj-168	39	4	-	-	PUNCT
anesthj-168	39	5	173	173	NUM
anesthj-168	39	6	6	6	NUM
anesthj-168	39	7	.	.	PUNCT
anesthj-168	40	1	hecht	hecht	PROPN
anesthj-168	40	2	p	p	NOUN
anesthj-168	40	3	,	,	PUNCT
anesthj-168	40	4	besser	besser	NOUN
anesthj-168	40	5	m	m	PROPN
anesthj-168	40	6	,	,	PUNCT
anesthj-168	40	7	falter	falter	VERB
anesthj-168	40	8	f.	f.	PROPN
anesthj-168	40	9	2020	2020	NUM
anesthj-168	40	10	.	.	PUNCT
anesthj-168	41	1	are	be	AUX
anesthj-168	41	2	we	we	PRON
anesthj-168	41	3	able	able	ADJ
anesthj-168	41	4	to	to	PART
anesthj-168	41	5	dose	dose	VERB
anesthj-168	41	6	protamine	protamine	NOUN
anesthj-168	41	7	accurately	accurately	ADV
anesthj-168	41	8	yet	yet	ADV
anesthj-168	41	9	?	?	PUNCT
anesthj-168	42	1	a	a	DET
anesthj-168	42	2	review	review	NOUN
anesthj-168	42	3	of	of	ADP
anesthj-168	42	4	the	the	DET
anesthj-168	42	5	protamine	protamine	NOUN
anesthj-168	42	6	conundrum	conundrum	NOUN
anesthj-168	42	7	.	.	PUNCT
anesthj-168	43	1	j	j	PROPN
anesthj-168	43	2	extra	extra	ADJ
anesthj-168	43	3	corpor	corpor	ADJ
anesthj-168	43	4	technol	technol	NOUN
anesthj-168	43	5	.	.	PUNCT
anesthj-168	44	1	52(1):63	52(1):63	NUM
anesthj-168	44	2	-	-	SYM
anesthj-168	44	3	70	70	NUM
anesthj-168	44	4	.	.	PUNCT
anesthj-168	45	1	doi:10.1182	doi:10.1182	NOUN
anesthj-168	45	2	/	/	SYM
anesthj-168	45	3	ject-1900038	ject-1900038	PROPN
anesthj-168	45	4	7	7	NUM
anesthj-168	45	5	.	.	X
anesthj-168	45	6	conti	conti	PROPN
anesthj-168	45	7	,	,	PUNCT
anesthj-168	45	8	v.r	v.r	PROPN
anesthj-168	45	9	.	.	PROPN
anesthj-168	45	10	,	,	PUNCT
anesthj-168	45	11	vertrees	vertree	NOUN
anesthj-168	45	12	,	,	PUNCT
anesthj-168	45	13	r.a	r.a	PROPN
anesthj-168	45	14	.	.	PROPN
anesthj-168	45	15	,	,	PUNCT
anesthj-168	45	16	zwischenberger	zwischenberger	NOUN
anesthj-168	45	17	,	,	PUNCT
anesthj-168	45	18	j.b	j.b	PROPN
anesthj-168	45	19	.	.	PROPN
anesthj-168	45	20	,	,	PUNCT
anesthj-168	45	21	kurusz	kurusz	PROPN
anesthj-168	45	22	,	,	PUNCT
anesthj-168	45	23	m.	m.	NOUN
anesthj-168	45	24	,	,	PUNCT
anesthj-168	45	25	1995	1995	NUM
anesthj-168	45	26	.	.	PUNCT
anesthj-168	46	1	first	first	ADJ
anesthj-168	46	2	clinical	clinical	ADJ
anesthj-168	46	3	use	use	NOUN
anesthj-168	46	4	of	of	ADP
anesthj-168	46	5	a	a	DET
anesthj-168	46	6	heparin	heparin	ADJ
anesthj-168	46	7	removal	removal	NOUN
anesthj-168	46	8	device	device	NOUN
anesthj-168	46	9	:	:	PUNCT
anesthj-168	46	10	an	an	DET
anesthj-168	46	11	alternative	alternative	NOUN
anesthj-168	46	12	to	to	ADP
anesthj-168	46	13	protamine	protamine	NOUN
anesthj-168	46	14	.	.	PUNCT
anesthj-168	47	1	j	j	PROPN
anesthj-168	47	2	thorac	thorac	PROPN
anesthj-168	47	3	cardiovasc	cardiovasc	PROPN
anesthj-168	47	4	surg	surg	PROPN
anesthj-168	47	5	.	.	PUNCT
anesthj-168	48	1	109	109	NUM
anesthj-168	48	2	,	,	PUNCT
anesthj-168	48	3	1015–1017	1015–1017	NUM
anesthj-168	48	4	..	..	PUNCT
anesthj-168	48	5	doi:10.1016	doi:10.1016	PROPN
anesthj-168	48	6	/	/	SYM
anesthj-168	48	7	s0022	s0022	PROPN
anesthj-168	48	8	-	-	PUNCT
anesthj-168	48	9	5223(95)70332	5223(95)70332	NUM
anesthj-168	48	10	-	-	PUNCT
anesthj-168	48	11	2	2	NUM
anesthj-168	48	12	8	8	NUM
anesthj-168	48	13	.	.	PUNCT
anesthj-168	49	1	tao	tao	PROPN
anesthj-168	49	2	w	w	PROPN
anesthj-168	49	3	,	,	PUNCT
anesthj-168	49	4	deyo	deyo	PROPN
anesthj-168	49	5	dj	dj	PROPN
anesthj-168	49	6	,	,	PUNCT
anesthj-168	49	7	brunston	brunston	PROPN
anesthj-168	49	8	rl	rl	PROPN
anesthj-168	49	9	jr	jr	PROPN
anesthj-168	49	10	,	,	PUNCT
anesthj-168	49	11	vertrees	vertree	NOUN
anesthj-168	49	12	ra	ra	PROPN
anesthj-168	49	13	,	,	PUNCT
anesthj-168	49	14	grochoske	grochoske	PROPN
anesthj-168	49	15	tl	tl	PROPN
anesthj-168	49	16	,	,	PUNCT
anesthj-168	49	17	zwischenberger	zwischenberger	NOUN
anesthj-168	49	18	jb	jb	PROPN
anesthj-168	49	19	.	.	PUNCT
anesthj-168	50	1	efficacy	efficacy	NOUN
anesthj-168	50	2	of	of	ADP
anesthj-168	50	3	a	a	DET
anesthj-168	50	4	heparin	heparin	ADJ
anesthj-168	50	5	removal	removal	NOUN
anesthj-168	50	6	device	device	NOUN
anesthj-168	50	7	in	in	ADP
anesthj-168	50	8	comparison	comparison	NOUN
anesthj-168	50	9	with	with	ADP
anesthj-168	50	10	protamine	protamine	NOUN
anesthj-168	50	11	after	after	ADP
anesthj-168	50	12	hypothermic	hypothermic	ADJ
anesthj-168	50	13	cardiopulmonary	cardiopulmonary	ADJ
anesthj-168	50	14	bypass	bypass	NOUN
anesthj-168	50	15	.	.	PUNCT
anesthj-168	51	1	asaio	asaio	PROPN
anesthj-168	51	2	j.	j.	PROPN
anesthj-168	51	3	1997;43(5):m825	1997;43(5):m825	PROPN
anesthj-168	51	4	-	-	PUNCT
anesthj-168	51	5	m830	m830	PROPN
anesthj-168	51	6	9	9	NUM
anesthj-168	51	7	.	.	PUNCT
anesthj-168	51	8	pearson	pearson	PROPN
anesthj-168	51	9	p	p	PROPN
anesthj-168	51	10	,	,	PUNCT
anesthj-168	51	11	evora	evora	PROPN
anesthj-168	51	12	p	p	PROPN
anesthj-168	51	13	,	,	PUNCT
anesthj-168	51	14	schaff	schaff	PROPN
anesthj-168	51	15	h	h	PROPN
anesthj-168	51	16	,	,	PUNCT
anesthj-168	52	1	et	et	PROPN
anesthj-168	52	2	al	al	PROPN
anesthj-168	52	3	.	.	PROPN
anesthj-168	52	4	protamine	protamine	PROPN
anesthj-168	52	5	releases	release	VERB
anesthj-168	52	6	endothelium‐derived	endothelium‐derive	VERB
anesthj-168	52	7	relaxing	relax	VERB
anesthj-168	52	8	factor	factor	NOUN
anesthj-168	52	9	from	from	ADP
anesthj-168	52	10	systemic	systemic	ADJ
anesthj-168	52	11	arteries	artery	NOUN
anesthj-168	52	12	:	:	PUNCT
anesthj-168	52	13	a	a	DET
anesthj-168	52	14	possible	possible	ADJ
anesthj-168	52	15	mechanism	mechanism	NOUN
anesthj-168	52	16	of	of	ADP
anesthj-168	52	17	hypotension	hypotension	NOUN
anesthj-168	52	18	during	during	ADP
anesthj-168	52	19	heparin	heparin	ADJ
anesthj-168	52	20	neutralization	neutralization	NOUN
anesthj-168	52	21	.	.	PUNCT
anesthj-168	53	1	circulation	circulation	NOUN
anesthj-168	53	2	.	.	PUNCT
anesthj-168	54	1	1992;86:289	1992;86:289	X
anesthj-168	54	2	-	-	PUNCT
anesthj-168	54	3	294	294	NUM
anesthj-168	54	4	.	.	PUNCT
anesthj-168	55	1	recommendations	recommendation	NOUN
anesthj-168	55	2	for	for	ADP
anesthj-168	55	3	practice	practice	NOUN
anesthj-168	55	4	•	•	NOUN
anesthj-168	55	5	set	set	VERB
anesthj-168	55	6	guidelines	guideline	NOUN
anesthj-168	55	7	to	to	PART
anesthj-168	55	8	run	run	VERB
anesthj-168	55	9	protamine	protamine	NOUN
anesthj-168	55	10	over	over	ADP
anesthj-168	55	11	at	at	ADV
anesthj-168	55	12	least	least	ADJ
anesthj-168	55	13	a	a	DET
anesthj-168	55	14	5–15minute	5–15minute	NUM
anesthj-168	55	15	time	time	NOUN
anesthj-168	55	16	frame2	frame2	NOUN
anesthj-168	55	17	•	•	NUM
anesthj-168	55	18	screen	screen	NOUN
anesthj-168	55	19	all	all	DET
anesthj-168	55	20	patients	patient	NOUN
anesthj-168	55	21	who	who	PRON
anesthj-168	55	22	will	will	AUX
anesthj-168	55	23	be	be	AUX
anesthj-168	55	24	given	give	VERB
anesthj-168	55	25	protamine	protamine	NOUN
anesthj-168	55	26	for	for	ADP
anesthj-168	55	27	risk	risk	NOUN
anesthj-168	55	28	factors	factor	NOUN
anesthj-168	55	29	of	of	ADP
anesthj-168	55	30	allergy	allergy	NOUN
anesthj-168	55	31	to	to	ADP
anesthj-168	55	32	fish	fish	NOUN
anesthj-168	55	33	,	,	PUNCT
anesthj-168	55	34	use	use	NOUN
anesthj-168	55	35	of	of	ADP
anesthj-168	55	36	nph	nph	NOUN
anesthj-168	55	37	insulins	insulin	NOUN
anesthj-168	55	38	,	,	PUNCT
anesthj-168	55	39	previous	previous	ADJ
anesthj-168	55	40	vasectomy	vasectomy	NOUN
anesthj-168	55	41	,	,	PUNCT
anesthj-168	55	42	and	and	CCONJ
anesthj-168	55	43	previous	previous	ADJ
anesthj-168	55	44	exposure	exposure	NOUN
anesthj-168	55	45	to	to	ADP
anesthj-168	55	46	protamine	protamine	ADJ
anesthj-168	55	47	recommendations	recommendation	NOUN
anesthj-168	55	48	for	for	ADP
anesthj-168	55	49	future	future	ADJ
anesthj-168	55	50	research	research	NOUN
anesthj-168	55	51	•	•	ADP
anesthj-168	55	52	further	further	ADJ
anesthj-168	55	53	studies	study	NOUN
anesthj-168	55	54	on	on	ADP
anesthj-168	55	55	the	the	DET
anesthj-168	55	56	use	use	NOUN
anesthj-168	55	57	of	of	ADP
anesthj-168	55	58	methylene	methylene	ADJ
anesthj-168	55	59	blue	blue	NOUN
anesthj-168	55	60	to	to	PART
anesthj-168	55	61	treat	treat	VERB
anesthj-168	55	62	hypotension	hypotension	NOUN
anesthj-168	55	63	after	after	ADP
anesthj-168	55	64	protamine	protamine	PROPN
anesthj-168	55	65	administration	administration	PROPN
anesthj-168	55	66	•	•	ADP
anesthj-168	55	67	further	further	ADJ
anesthj-168	55	68	studies	study	NOUN
anesthj-168	55	69	on	on	ADP
anesthj-168	55	70	the	the	DET
anesthj-168	55	71	use	use	NOUN
anesthj-168	55	72	of	of	ADP
anesthj-168	55	73	a	a	DET
anesthj-168	55	74	heparin	heparin	ADJ
anesthj-168	55	75	removal	removal	NOUN
anesthj-168	55	76	device	device	NOUN
anesthj-168	55	77	to	to	PART
anesthj-168	55	78	determine	determine	VERB
anesthj-168	55	79	efficacy	efficacy	NOUN
anesthj-168	55	80	and	and	CCONJ
anesthj-168	55	81	appropriateness	appropriateness	NOUN
anesthj-168	55	82	of	of	ADP
anesthj-168	55	83	its	its	PRON
anesthj-168	55	84	use	use	NOUN
anesthj-168	55	85	with	with	ADP
anesthj-168	55	86	known	know	VERB
anesthj-168	55	87	protamine	protamine	NOUN
anesthj-168	55	88	allergies	allergy	NOUN
anesthj-168	55	89	•	•	ADP
anesthj-168	55	90	further	further	ADJ
anesthj-168	55	91	studies	study	NOUN
anesthj-168	55	92	to	to	PART
anesthj-168	55	93	assess	assess	VERB
anesthj-168	55	94	appropriate	appropriate	ADJ
anesthj-168	55	95	dosing	dosing	NOUN
anesthj-168	55	96	of	of	ADP
anesthj-168	55	97	protamine	protamine	NOUN
anesthj-168	55	98	risk	risk	NOUN
anesthj-168	55	99	factors	factor	NOUN
anesthj-168	55	100	for	for	ADP
anesthj-168	55	101	a	a	DET
anesthj-168	55	102	protamine	protamine	NOUN
anesthj-168	55	103	reaction	reaction	NOUN
anesthj-168	55	104	q	q	PROPN
anesthj-168	55	105	allergy	allergy	NOUN
anesthj-168	55	106	to	to	AUX
anesthj-168	55	107	fish2	fish2	NOUN
anesthj-168	55	108	q	q	NOUN
anesthj-168	55	109	use	use	NOUN
anesthj-168	55	110	of	of	ADP
anesthj-168	55	111	nph	nph	PROPN
anesthj-168	55	112	insulins2	insulins2	PROPN
anesthj-168	55	113	q	q	PROPN
anesthj-168	55	114	previous	previous	ADJ
anesthj-168	55	115	vasectomy2	vasectomy2	NOUN
anesthj-168	55	116	q	q	NOUN
anesthj-168	55	117	previous	previous	ADJ
anesthj-168	55	118	exposure	exposure	NOUN
anesthj-168	55	119	to	to	ADP
anesthj-168	55	120	protamine	protamine	PROPN
anesthj-168	55	121	sulfate2	sulfate2	PROPN
anesthj-168	55	122	q	q	PROPN
anesthj-168	55	123	rapid	rapid	ADJ
anesthj-168	55	124	administration	administration	NOUN
anesthj-168	55	125	of	of	ADP
anesthj-168	55	126	protamine	protamine	PROPN
anesthj-168	55	127	sulfate2	sulfate2	PROPN
anesthj-168	55	128	f	f	PROPN
anesthj-168	55	129	supportive	supportive	ADJ
anesthj-168	55	130	evidence	evidence	NOUN
anesthj-168	55	131	•	•	ADP
anesthj-168	55	132	a	a	DET
anesthj-168	55	133	retrospective	retrospective	ADJ
anesthj-168	55	134	analysis	analysis	NOUN
anesthj-168	55	135	by	by	ADP
anesthj-168	55	136	porsche	porsche	PROPN
anesthj-168	55	137	et	et	PROPN
anesthj-168	55	138	al	al	PROPN
anesthj-168	55	139	assessed	assess	VERB
anesthj-168	55	140	incidence	incidence	NOUN
anesthj-168	55	141	and	and	CCONJ
anesthj-168	55	142	symptoms	symptom	NOUN
anesthj-168	55	143	associated	associate	VERB
anesthj-168	55	144	with	with	ADP
anesthj-168	55	145	protamine.2	protamine.2	PROPN
anesthj-168	55	146	a	a	DET
anesthj-168	55	147	reaction	reaction	NOUN
anesthj-168	55	148	occurred	occur	VERB
anesthj-168	55	149	between	between	ADP
anesthj-168	55	150	0.06	0.06	NUM
anesthj-168	55	151	%	%	NOUN
anesthj-168	55	152	and	and	CCONJ
anesthj-168	55	153	10.7%.2	10.7%.2	NUM
anesthj-168	55	154	different	different	ADJ
anesthj-168	55	155	reactions	reaction	NOUN
anesthj-168	55	156	ranged	range	VERB
anesthj-168	55	157	from	from	ADP
anesthj-168	55	158	hypotension	hypotension	NOUN
anesthj-168	55	159	,	,	PUNCT
anesthj-168	55	160	increases	increase	NOUN
anesthj-168	55	161	in	in	ADP
anesthj-168	55	162	pulmonary	pulmonary	ADJ
anesthj-168	55	163	artery	artery	NOUN
anesthj-168	55	164	pressure	pressure	NOUN
anesthj-168	55	165	,	,	PUNCT
anesthj-168	55	166	bronchospasm	bronchospasm	NOUN
anesthj-168	55	167	,	,	PUNCT
anesthj-168	55	168	flushing	flush	VERB
anesthj-168	55	169	,	,	PUNCT
anesthj-168	55	170	angioedema	angioedema	VERB
anesthj-168	55	171	,	,	PUNCT
anesthj-168	55	172	erythema	erythema	ADJ
anesthj-168	55	173	,	,	PUNCT
anesthj-168	55	174	and	and	CCONJ
anesthj-168	55	175	pruritus	pruritus	PROPN
anesthj-168	55	176	,	,	PUNCT
anesthj-168	55	177	chills	chill	NOUN
anesthj-168	55	178	,	,	PUNCT
anesthj-168	55	179	chest	chest	NOUN
anesthj-168	55	180	pain	pain	NOUN
anesthj-168	55	181	,	,	PUNCT
anesthj-168	55	182	or	or	CCONJ
anesthj-168	55	183	nausea	nausea	NOUN
anesthj-168	55	184	and	and	CCONJ
anesthj-168	55	185	vomiting2	vomiting2	NOUN
anesthj-168	55	186	•	•	ADP
anesthj-168	55	187	a	a	DET
anesthj-168	55	188	prospective	prospective	ADJ
anesthj-168	55	189	study	study	NOUN
anesthj-168	55	190	by	by	ADP
anesthj-168	55	191	weiler	weiler	PROPN
anesthj-168	55	192	et	et	PROPN
anesthj-168	55	193	al	al	PROPN
anesthj-168	55	194	examined	examine	VERB
anesthj-168	55	195	incidence	incidence	NOUN
anesthj-168	55	196	of	of	ADP
anesthj-168	55	197	protamine	protamine	NOUN
anesthj-168	55	198	reaction.3	reaction.3	PROPN
anesthj-168	55	199	248	248	NUM
anesthj-168	55	200	patients	patient	NOUN
anesthj-168	55	201	were	be	AUX
anesthj-168	55	202	given	give	VERB
anesthj-168	55	203	protamine	protamine	NOUN
anesthj-168	55	204	,	,	PUNCT
anesthj-168	55	205	26	26	NUM
anesthj-168	55	206	experienced	experience	VERB
anesthj-168	55	207	a	a	DET
anesthj-168	55	208	reaction	reaction	NOUN
anesthj-168	55	209	(	(	PUNCT
anesthj-168	55	210	10.7%).3	10.7%).3	NUM
anesthj-168	55	211	a	a	DET
anesthj-168	55	212	reaction	reaction	NOUN
anesthj-168	55	213	was	be	AUX
anesthj-168	55	214	considered	consider	VERB
anesthj-168	55	215	mild	mild	ADJ
anesthj-168	55	216	(	(	PUNCT
anesthj-168	55	217	20	20	NUM
anesthj-168	55	218	-	-	SYM
anesthj-168	55	219	29	29	NUM
anesthj-168	55	220	mmhg	mmhg	NOUN
anesthj-168	55	221	decrease	decrease	NOUN
anesthj-168	55	222	in	in	ADP
anesthj-168	55	223	sbp	sbp	NOUN
anesthj-168	55	224	)	)	PUNCT
anesthj-168	55	225	,	,	PUNCT
anesthj-168	55	226	moderate	moderate	ADJ
anesthj-168	55	227	(	(	PUNCT
anesthj-168	55	228	30	30	NUM
anesthj-168	55	229	-	-	SYM
anesthj-168	55	230	49	49	NUM
anesthj-168	55	231	mmhg	mmhg	NOUN
anesthj-168	55	232	decrease	decrease	NOUN
anesthj-168	55	233	in	in	ADP
anesthj-168	55	234	sbp	sbp	NOUN
anesthj-168	55	235	)	)	PUNCT
anesthj-168	55	236	,	,	PUNCT
anesthj-168	55	237	or	or	CCONJ
anesthj-168	55	238	severe	severe	ADJ
anesthj-168	55	239	(	(	PUNCT
anesthj-168	55	240	50	50	NUM
anesthj-168	55	241	mmhg	mmhg	NOUN
anesthj-168	55	242	decrease	decrease	NOUN
anesthj-168	55	243	in	in	ADP
anesthj-168	55	244	sbp).3	sbp).3	NUM
anesthj-168	55	245	eleven	eleven	NUM
anesthj-168	55	246	of	of	ADP
anesthj-168	55	247	the	the	DET
anesthj-168	55	248	reactions	reaction	NOUN
anesthj-168	55	249	were	be	AUX
anesthj-168	55	250	mild	mild	ADJ
anesthj-168	55	251	,	,	PUNCT
anesthj-168	55	252	9	9	NUM
anesthj-168	55	253	were	be	AUX
anesthj-168	55	254	moderate	moderate	ADJ
anesthj-168	55	255	,	,	PUNCT
anesthj-168	55	256	and	and	CCONJ
anesthj-168	55	257	4	4	NUM
anesthj-168	55	258	were	be	AUX
anesthj-168	55	259	severe.3	severe.3	PROPN
anesthj-168	55	260	patient	patient	ADJ
anesthj-168	55	261	risk	risk	NOUN
anesthj-168	55	262	factors	factor	NOUN
anesthj-168	55	263	and	and	CCONJ
anesthj-168	55	264	statistical	statistical	ADJ
anesthj-168	55	265	significance	significance	NOUN
anesthj-168	55	266	were	be	AUX
anesthj-168	55	267	also	also	ADV
anesthj-168	55	268	significant	significant	ADJ
anesthj-168	55	269	for	for	ADP
anesthj-168	55	270	t2	t2	NOUN
anesthj-168	55	271	dm	dm	PROPN
anesthj-168	55	272	and	and	CCONJ
anesthj-168	55	273	received	receive	VERB
anesthj-168	55	274	protamine	protamine	NOUN
anesthj-168	55	275	-	-	PUNCT
anesthj-168	55	276	containing	contain	VERB
anesthj-168	55	277	insulin3	insulin3	NOUN
anesthj-168	55	278	•	•	ADP
anesthj-168	55	279	a	a	DET
anesthj-168	55	280	sr	sr	NOUN
anesthj-168	55	281	by	by	ADP
anesthj-168	55	282	nybo	nybo	NOUN
anesthj-168	55	283	m	m	VERB
anesthj-168	55	284	et	et	PROPN
anesthj-168	55	285	al	al	PROPN
anesthj-168	55	286	examined	examine	VERB
anesthj-168	55	287	incidence	incidence	NOUN
anesthj-168	55	288	of	of	ADP
anesthj-168	55	289	anaphylactic	anaphylactic	ADJ
anesthj-168	55	290	reactions	reaction	NOUN
anesthj-168	55	291	after	after	ADP
anesthj-168	55	292	the	the	DET
anesthj-168	55	293	administration	administration	NOUN
anesthj-168	55	294	of	of	ADP
anesthj-168	55	295	protamine	protamine	PROPN
anesthj-168	55	296	sulfate.4	sulfate.4	NOUN
anesthj-168	55	297	nine	nine	NUM
anesthj-168	55	298	retrospective	retrospective	ADJ
anesthj-168	55	299	studies	study	NOUN
anesthj-168	55	300	found	find	VERB
anesthj-168	55	301	(	(	PUNCT
anesthj-168	55	302	0.19	0.19	NUM
anesthj-168	55	303	%	%	NOUN
anesthj-168	55	304	)	)	PUNCT
anesthj-168	55	305	anaphylaxis	anaphylaxis	ADJ
anesthj-168	55	306	,	,	PUNCT
anesthj-168	55	307	16	16	NUM
anesthj-168	55	308	prospective	prospective	ADJ
anesthj-168	55	309	studies	study	NOUN
anesthj-168	55	310	found	find	VERB
anesthj-168	55	311	anaphylaxis	anaphylaxis	ADJ
anesthj-168	55	312	(	(	PUNCT
anesthj-168	55	313	0.69%).4	0.69%).4	NUM
anesthj-168	55	314	prior	prior	ADJ
anesthj-168	55	315	treatment	treatment	NOUN
anesthj-168	55	316	with	with	ADP
anesthj-168	55	317	nph	nph	PROPN
anesthj-168	55	318	insulin	insulin	NOUN
anesthj-168	55	319	was	be	AUX
anesthj-168	55	320	the	the	DET
anesthj-168	55	321	most	most	ADV
anesthj-168	55	322	common	common	ADJ
anesthj-168	55	323	predisposing	predispose	VERB
anesthj-168	55	324	factor	factor	NOUN
anesthj-168	55	325	to	to	PART
anesthj-168	55	326	suffer	suffer	VERB
anesthj-168	55	327	an	an	DET
anesthj-168	55	328	anaphylactic	anaphylactic	ADJ
anesthj-168	55	329	reaction4	reaction4	NOUN
anesthj-168	55	330	•	•	NUM
anesthj-168	56	1	hecht	hecht	PROPN
anesthj-168	56	2	p	p	PROPN
anesthj-168	56	3	et	et	PROPN
anesthj-168	56	4	al	al	PROPN
anesthj-168	56	5	examined	examine	VERB
anesthj-168	56	6	optimal	optimal	ADJ
anesthj-168	56	7	protamine	protamine	NOUN
anesthj-168	56	8	dosing.6	dosing.6	NOUN
anesthj-168	56	9	fixed	fix	VERB
anesthj-168	56	10	-	-	PUNCT
anesthj-168	56	11	protamine	protamine	NOUN
anesthj-168	56	12	:	:	PUNCT
anesthj-168	56	13	heparin	heparin	ADJ
anesthj-168	56	14	ratio	ratio	NOUN
anesthj-168	56	15	dose	dose	NOUN
anesthj-168	56	16	is	be	AUX
anesthj-168	56	17	one	one	NUM
anesthj-168	56	18	of	of	ADP
anesthj-168	56	19	the	the	DET
anesthj-168	56	20	most	most	ADV
anesthj-168	56	21	common	common	ADJ
anesthj-168	56	22	strategies	strategy	NOUN
anesthj-168	56	23	utilizing	utilize	VERB
anesthj-168	56	24	1	1	NUM
anesthj-168	56	25	mg	mg	NOUN
anesthj-168	56	26	of	of	ADP
anesthj-168	56	27	protamine	protamine	NOUN
anesthj-168	56	28	for	for	ADP
anesthj-168	56	29	every	every	DET
anesthj-168	56	30	100	100	NUM
anesthj-168	56	31	units	unit	NOUN
anesthj-168	56	32	of	of	ADP
anesthj-168	56	33	heparin.6	heparin.6	NOUN
anesthj-168	56	34	the	the	DET
anesthj-168	56	35	act	act	NOUN
anesthj-168	56	36	-	-	PUNCT
anesthj-168	56	37	based	base	VERB
anesthj-168	56	38	model	model	NOUN
anesthj-168	56	39	is	be	AUX
anesthj-168	56	40	discussed	discuss	VERB
anesthj-168	56	41	incorporating	incorporate	VERB
anesthj-168	56	42	a	a	DET
anesthj-168	56	43	mathematical	mathematical	ADJ
anesthj-168	56	44	relationship	relationship	NOUN
anesthj-168	56	45	to	to	PART
anesthj-168	56	46	help	help	VERB
anesthj-168	56	47	determine	determine	VERB
anesthj-168	56	48	the	the	DET
anesthj-168	56	49	appropriate	appropriate	ADJ
anesthj-168	56	50	protamine	protamine	NOUN
anesthj-168	56	51	dose	dose	VERB
anesthj-168	56	52	based	base	VERB
anesthj-168	56	53	on	on	ADP
anesthj-168	56	54	act	act	NOUN
anesthj-168	56	55	levels	level	NOUN
anesthj-168	56	56	measured	measure	VERB
anesthj-168	56	57	at	at	ADP
anesthj-168	56	58	baseline	baseline	NOUN
anesthj-168	56	59	,	,	PUNCT
anesthj-168	56	60	before	before	ADP
anesthj-168	56	61	cpb	cpb	PROPN
anesthj-168	56	62	,	,	PUNCT
anesthj-168	56	63	and	and	CCONJ
anesthj-168	56	64	pre	pre	ADJ
anesthj-168	56	65	-	-	NOUN
anesthj-168	56	66	protamine	protamine	ADJ
anesthj-168	56	67	as	as	ADV
anesthj-168	56	68	well	well	ADV
anesthj-168	56	69	as	as	ADP
anesthj-168	56	70	initial	initial	ADJ
anesthj-168	56	71	heparin	heparin	ADJ
anesthj-168	56	72	dose	dose	NOUN
anesthj-168	56	73	and	and	CCONJ
anesthj-168	56	74	patient	patient	NOUN
anesthj-168	56	75	’s	’s	PART
anesthj-168	56	76	weight.6	weight.6	NOUN
anesthj-168	56	77	the	the	DET
anesthj-168	56	78	act	act	NOUN
anesthj-168	56	79	-	-	PUNCT
anesthj-168	56	80	based	base	VERB
anesthj-168	56	81	model	model	NOUN
anesthj-168	56	82	found	find	VERB
anesthj-168	56	83	on	on	ADP
anesthj-168	56	84	average	average	ADJ
anesthj-168	56	85	a	a	DET
anesthj-168	56	86	40	40	NUM
anesthj-168	56	87	mg	mg	NOUN
anesthj-168	56	88	reduction	reduction	NOUN
anesthj-168	56	89	in	in	ADP
anesthj-168	56	90	protamine	protamine	PROPN
anesthj-168	56	91	dose	dose	VERB
anesthj-168	56	92	required6	required6	PROPN
anesthj-168	56	93	•	•	ADP
anesthj-168	56	94	a	a	DET
anesthj-168	56	95	randomized	randomized	ADJ
anesthj-168	56	96	controlled	control	VERB
anesthj-168	56	97	trial	trial	NOUN
anesthj-168	56	98	assessed	assess	VERB
anesthj-168	56	99	12	12	NUM
anesthj-168	56	100	yorkshire	yorkshire	ADJ
anesthj-168	56	101	female	female	ADJ
anesthj-168	56	102	swine	swine	NOUN
anesthj-168	56	103	for	for	ADP
anesthj-168	56	104	heparin	heparin	ADJ
anesthj-168	56	105	removal	removal	NOUN
anesthj-168	56	106	device	device	NOUN
anesthj-168	56	107	efficacy	efficacy	NOUN
anesthj-168	56	108	compared	compare	VERB
anesthj-168	56	109	to	to	ADP
anesthj-168	56	110	protamine	protamine	NOUN
anesthj-168	56	111	administration.8	administration.8	PROPN
anesthj-168	56	112	six	six	NUM
anesthj-168	56	113	were	be	AUX
anesthj-168	56	114	randomly	randomly	ADV
anesthj-168	56	115	allocated	allocate	VERB
anesthj-168	56	116	to	to	ADP
anesthj-168	56	117	a	a	DET
anesthj-168	56	118	protamine	protamine	NOUN
anesthj-168	56	119	group	group	NOUN
anesthj-168	56	120	,	,	PUNCT
anesthj-168	56	121	which	which	PRON
anesthj-168	56	122	were	be	AUX
anesthj-168	56	123	given	give	VERB
anesthj-168	56	124	1	1	NUM
anesthj-168	56	125	mg	mg	ADP
anesthj-168	56	126	of	of	ADP
anesthj-168	56	127	protamine	protamine	NOUN
anesthj-168	56	128	for	for	ADP
anesthj-168	56	129	every	every	DET
anesthj-168	56	130	100	100	NUM
anesthj-168	56	131	units	unit	NOUN
anesthj-168	56	132	of	of	ADP
anesthj-168	56	133	heparin	heparin	NOUN
anesthj-168	56	134	and	and	CCONJ
anesthj-168	56	135	the	the	DET
anesthj-168	56	136	other	other	ADJ
anesthj-168	56	137	6	6	NUM
anesthj-168	56	138	were	be	AUX
anesthj-168	56	139	allocated	allocate	VERB
anesthj-168	56	140	to	to	ADP
anesthj-168	56	141	the	the	DET
anesthj-168	56	142	heparin	heparin	ADJ
anesthj-168	56	143	removal	removal	NOUN
anesthj-168	56	144	device	device	NOUN
anesthj-168	56	145	group	group	NOUN
anesthj-168	56	146	,	,	PUNCT
anesthj-168	56	147	that	that	PRON
anesthj-168	56	148	had	have	VERB
anesthj-168	56	149	a	a	DET
anesthj-168	56	150	target	target	NOUN
anesthj-168	56	151	of	of	ADP
anesthj-168	56	152	90	90	NUM
anesthj-168	56	153	%	%	NOUN
anesthj-168	56	154	heparin	heparin	ADJ
anesthj-168	56	155	removal.8	removal.8	PROPN
anesthj-168	56	156	no	no	DET
anesthj-168	56	157	statistically	statistically	ADV
anesthj-168	56	158	significant	significant	ADJ
anesthj-168	56	159	changes	change	NOUN
anesthj-168	56	160	in	in	ADP
anesthj-168	56	161	hemodynamics	hemodynamic	NOUN
anesthj-168	56	162	were	be	AUX
anesthj-168	56	163	associated	associate	VERB
anesthj-168	56	164	with	with	ADP
anesthj-168	56	165	use	use	NOUN
anesthj-168	56	166	of	of	ADP
anesthj-168	56	167	the	the	DET
anesthj-168	56	168	heparin	heparin	ADJ
anesthj-168	56	169	removal	removal	NOUN
anesthj-168	56	170	device.8	device.8	VERB
anesthj-168	57	1	the	the	DET
anesthj-168	57	2	study	study	NOUN
anesthj-168	57	3	found	find	VERB
anesthj-168	57	4	that	that	SCONJ
anesthj-168	57	5	the	the	DET
anesthj-168	57	6	heparin	heparin	ADJ
anesthj-168	57	7	removal	removal	NOUN
anesthj-168	57	8	device	device	NOUN
anesthj-168	57	9	was	be	AUX
anesthj-168	57	10	able	able	ADJ
anesthj-168	57	11	to	to	PART
anesthj-168	57	12	reverse	reverse	VERB
anesthj-168	57	13	systemic	systemic	ADJ
anesthj-168	57	14	heparin	heparin	ADJ
anesthj-168	57	15	anticoagulation	anticoagulation	NOUN
anesthj-168	57	16	by	by	ADP
anesthj-168	57	17	returning	return	VERB
anesthj-168	57	18	pt	pt	PROPN
anesthj-168	57	19	,	,	PUNCT
anesthj-168	57	20	aptt	aptt	ADJ
anesthj-168	57	21	,	,	PUNCT
anesthj-168	57	22	act	act	NOUN
anesthj-168	57	23	and	and	CCONJ
anesthj-168	57	24	heparin	heparin	ADJ
anesthj-168	57	25	concentration	concentration	NOUN
anesthj-168	57	26	to	to	ADP
anesthj-168	57	27	near	near	ADP
anesthj-168	57	28	baseline	baseline	ADJ
anesthj-168	57	29	levels	level	NOUN
anesthj-168	57	30	after	after	ADP
anesthj-168	57	31	an	an	DET
anesthj-168	57	32	average	average	ADJ
anesthj-168	57	33	run	run	NOUN
anesthj-168	57	34	time	time	NOUN
anesthj-168	57	35	of	of	ADP
anesthj-168	57	36	31.5	31.5	NUM
anesthj-168	57	37	minutes8	minutes8	NOUN
anesthj-168	57	38	•	•	NOUN
anesthj-168	57	39	a	a	DET
anesthj-168	57	40	case	case	NOUN
anesthj-168	57	41	study	study	NOUN
anesthj-168	57	42	by	by	ADP
anesthj-168	57	43	conti	conti	PROPN
anesthj-168	57	44	et	et	PROPN
anesthj-168	57	45	al	al	PROPN
anesthj-168	57	46	examined	examine	VERB
anesthj-168	57	47	of	of	ADP
anesthj-168	57	48	the	the	DET
anesthj-168	57	49	first	first	ADJ
anesthj-168	57	50	use	use	NOUN
anesthj-168	57	51	of	of	ADP
anesthj-168	57	52	a	a	DET
anesthj-168	57	53	heparin	heparin	ADJ
anesthj-168	57	54	removal	removal	NOUN
anesthj-168	57	55	device.7	device.7	NOUN
anesthj-168	57	56	a	a	DET
anesthj-168	57	57	44	44	NUM
anesthj-168	57	58	-	-	PUNCT
anesthj-168	57	59	year	year	NOUN
anesthj-168	57	60	-	-	PUNCT
anesthj-168	57	61	old	old	ADJ
anesthj-168	57	62	woman	woman	NOUN
anesthj-168	57	63	with	with	ADP
anesthj-168	57	64	a	a	DET
anesthj-168	57	65	history	history	NOUN
anesthj-168	57	66	of	of	ADP
anesthj-168	57	67	diabetes	diabetes	NOUN
anesthj-168	57	68	that	that	PRON
anesthj-168	57	69	was	be	AUX
anesthj-168	57	70	on	on	ADP
anesthj-168	57	71	nph	nph	NOUN
anesthj-168	57	72	insulin	insulin	NOUN
anesthj-168	57	73	underwent	underwent	NOUN
anesthj-168	57	74	a	a	DET
anesthj-168	57	75	cabg.7	cabg.7	NOUN
anesthj-168	57	76	a	a	DET
anesthj-168	57	77	test	test	NOUN
anesthj-168	57	78	dose	dose	NOUN
anesthj-168	57	79	of	of	ADP
anesthj-168	57	80	protamine	protamine	PROPN
anesthj-168	57	81	was	be	AUX
anesthj-168	57	82	given	give	VERB
anesthj-168	57	83	,	,	PUNCT
anesthj-168	57	84	which	which	PRON
anesthj-168	57	85	resulted	result	VERB
anesthj-168	57	86	in	in	ADP
anesthj-168	57	87	a	a	DET
anesthj-168	57	88	rapid	rapid	ADJ
anesthj-168	57	89	decrease	decrease	NOUN
anesthj-168	57	90	in	in	ADP
anesthj-168	57	91	sbp	sbp	NOUN
anesthj-168	57	92	from	from	ADP
anesthj-168	57	93	130	130	NUM
anesthj-168	57	94	to	to	ADP
anesthj-168	57	95	below	below	ADP
anesthj-168	57	96	40	40	NUM
anesthj-168	57	97	mmhg	mmhg	NOUN
anesthj-168	57	98	,	,	PUNCT
anesthj-168	57	99	and	and	CCONJ
anesthj-168	57	100	an	an	DET
anesthj-168	57	101	increase	increase	NOUN
anesthj-168	57	102	in	in	ADP
anesthj-168	57	103	the	the	DET
anesthj-168	57	104	pap	pap	NOUN
anesthj-168	57	105	to	to	ADP
anesthj-168	57	106	52	52	NUM
anesthj-168	57	107	mmhg	mmhg	NOUN
anesthj-168	57	108	,	,	PUNCT
anesthj-168	57	109	along	along	ADP
anesthj-168	57	110	with	with	ADP
anesthj-168	57	111	right	right	ADJ
anesthj-168	57	112	heart	heart	NOUN
anesthj-168	57	113	failure.7	failure.7	NOUN
anesthj-168	57	114	open	open	ADJ
anesthj-168	57	115	cardiac	cardiac	ADJ
anesthj-168	57	116	massage	massage	NOUN
anesthj-168	57	117	and	and	CCONJ
anesthj-168	57	118	an	an	DET
anesthj-168	57	119	epinephrine	epinephrine	NOUN
anesthj-168	57	120	infusion	infusion	NOUN
anesthj-168	57	121	were	be	AUX
anesthj-168	57	122	initiated	initiate	VERB
anesthj-168	57	123	,	,	PUNCT
anesthj-168	57	124	and	and	CCONJ
anesthj-168	57	125	hemodynamics	hemodynamic	NOUN
anesthj-168	57	126	were	be	AUX
anesthj-168	57	127	stabilized	stabilize	VERB
anesthj-168	57	128	after	after	ADP
anesthj-168	57	129	5	5	NUM
anesthj-168	57	130	minutes.7	minutes.7	NOUN
anesthj-168	57	131	the	the	DET
anesthj-168	57	132	chest	chest	NOUN
anesthj-168	57	133	was	be	AUX
anesthj-168	57	134	closed	close	VERB
anesthj-168	57	135	and	and	CCONJ
anesthj-168	57	136	the	the	DET
anesthj-168	57	137	patient	patient	NOUN
anesthj-168	57	138	was	be	AUX
anesthj-168	57	139	taken	take	VERB
anesthj-168	57	140	to	to	ADP
anesthj-168	57	141	the	the	DET
anesthj-168	57	142	icu	icu	PROPN
anesthj-168	57	143	with	with	ADP
anesthj-168	57	144	an	an	DET
anesthj-168	57	145	act	act	NOUN
anesthj-168	57	146	of	of	ADP
anesthj-168	57	147	459	459	NUM
anesthj-168	57	148	seconds.7	seconds.7	PROPN
anesthj-168	57	149	extensive	extensive	ADJ
anesthj-168	57	150	bleeding	bleeding	NOUN
anesthj-168	57	151	occurred	occur	VERB
anesthj-168	57	152	and	and	CCONJ
anesthj-168	57	153	the	the	DET
anesthj-168	57	154	patient	patient	NOUN
anesthj-168	57	155	was	be	AUX
anesthj-168	57	156	taken	take	VERB
anesthj-168	57	157	back	back	ADV
anesthj-168	57	158	to	to	ADP
anesthj-168	57	159	the	the	PRON
anesthj-168	57	160	or	or	CCONJ
anesthj-168	57	161	where	where	SCONJ
anesthj-168	57	162	the	the	DET
anesthj-168	57	163	decision	decision	NOUN
anesthj-168	57	164	was	be	AUX
anesthj-168	57	165	made	make	VERB
anesthj-168	57	166	to	to	PART
anesthj-168	57	167	use	use	VERB
anesthj-168	57	168	a	a	DET
anesthj-168	57	169	heparin	heparin	ADJ
anesthj-168	57	170	removal	removal	NOUN
anesthj-168	57	171	device.7	device.7	NOUN
anesthj-168	57	172	after	after	ADP
anesthj-168	57	173	a	a	DET
anesthj-168	57	174	run	run	ADJ
anesthj-168	57	175	time	time	NOUN
anesthj-168	57	176	of	of	ADP
anesthj-168	57	177	25	25	NUM
anesthj-168	57	178	minutes	minute	NOUN
anesthj-168	57	179	the	the	DET
anesthj-168	57	180	act	act	NOUN
anesthj-168	57	181	was	be	AUX
anesthj-168	57	182	160	160	NUM
anesthj-168	57	183	seconds	second	NOUN
anesthj-168	57	184	,	,	PUNCT
anesthj-168	57	185	which	which	PRON
anesthj-168	57	186	was	be	AUX
anesthj-168	57	187	below	below	ADP
anesthj-168	57	188	the	the	DET
anesthj-168	57	189	baseline	baseline	NOUN
anesthj-168	57	190	of	of	ADP
anesthj-168	57	191	192	192	NUM
anesthj-168	57	192	seconds7	seconds7	X
anesthj-168	57	193	•	•	ADP
anesthj-168	57	194	a	a	DET
anesthj-168	57	195	case	case	NOUN
anesthj-168	57	196	study	study	NOUN
anesthj-168	57	197	by	by	ADP
anesthj-168	57	198	lutjen	lutjen	PROPN
anesthj-168	57	199	and	and	CCONJ
anesthj-168	57	200	arndt	arndt	PROPN
anesthj-168	57	201	examined	examine	VERB
anesthj-168	57	202	a	a	DET
anesthj-168	57	203	57	57	NUM
anesthj-168	57	204	-	-	PUNCT
anesthj-168	57	205	year	year	NOUN
anesthj-168	57	206	-	-	PUNCT
anesthj-168	57	207	old	old	ADJ
anesthj-168	57	208	woman	woman	NOUN
anesthj-168	57	209	undergoing	undergo	VERB
anesthj-168	57	210	a	a	DET
anesthj-168	57	211	cabg	cabg	NOUN
anesthj-168	57	212	that	that	PRON
anesthj-168	57	213	suffered	suffer	VERB
anesthj-168	57	214	a	a	DET
anesthj-168	57	215	protamine	protamine	NOUN
anesthj-168	57	216	reaction	reaction	NOUN
anesthj-168	57	217	.	.	PUNCT
anesthj-168	58	1	after	after	ADP
anesthj-168	58	2	80	80	NUM
anesthj-168	58	3	%	%	NOUN
anesthj-168	58	4	of	of	ADP
anesthj-168	58	5	the	the	DET
anesthj-168	58	6	infusion	infusion	NOUN
anesthj-168	58	7	,	,	PUNCT
anesthj-168	58	8	sbp	sbp	PROPN
anesthj-168	58	9	dropped	drop	VERB
anesthj-168	58	10	rapidly	rapidly	ADV
anesthj-168	58	11	from	from	ADP
anesthj-168	58	12	120	120	NUM
anesthj-168	58	13	to	to	PART
anesthj-168	58	14	62	62	NUM
anesthj-168	58	15	mmhg	mmhg	NOUN
anesthj-168	58	16	,	,	PUNCT
anesthj-168	58	17	and	and	CCONJ
anesthj-168	58	18	eventually	eventually	ADV
anesthj-168	58	19	to	to	ADP
anesthj-168	58	20	as	as	ADV
anesthj-168	58	21	low	low	ADJ
anesthj-168	58	22	as	as	ADP
anesthj-168	58	23	50	50	NUM
anesthj-168	58	24	mmhg.5	mmhg.5	NOUN
anesthj-168	58	25	the	the	DET
anesthj-168	58	26	pap	pap	NOUN
anesthj-168	58	27	rose	rise	VERB
anesthj-168	58	28	from	from	ADP
anesthj-168	58	29	17/8	17/8	NUM
anesthj-168	58	30	mmhg	mmhg	PROPN
anesthj-168	58	31	to	to	ADP
anesthj-168	58	32	28/16	28/16	NUM
anesthj-168	58	33	mmhg.5	mmhg.5	NOUN
anesthj-168	58	34	aggressive	aggressive	ADJ
anesthj-168	58	35	treatment	treatment	NOUN
anesthj-168	58	36	with	with	ADP
anesthj-168	58	37	vasopressors	vasopressor	NOUN
anesthj-168	58	38	,	,	PUNCT
anesthj-168	58	39	fluids	fluid	NOUN
anesthj-168	58	40	,	,	PUNCT
anesthj-168	58	41	blood	blood	NOUN
anesthj-168	58	42	products	product	NOUN
anesthj-168	58	43	,	,	PUNCT
anesthj-168	58	44	and	and	CCONJ
anesthj-168	58	45	iv	iv	NUM
anesthj-168	58	46	steroids	steroid	NOUN
anesthj-168	58	47	maintained	maintain	VERB
anesthj-168	58	48	sbp	sbp	NOUN
anesthj-168	58	49	between	between	ADP
anesthj-168	58	50	50	50	NUM
anesthj-168	58	51	and	and	CCONJ
anesthj-168	58	52	60	60	NUM
anesthj-168	58	53	mmhg.5	mmhg.5	PROPN
anesthj-168	58	54	methylene	methylene	NOUN
anesthj-168	58	55	blue	blue	NOUN
anesthj-168	58	56	,	,	PUNCT
anesthj-168	58	57	500	500	NUM
anesthj-168	58	58	mg	mg	NOUN
anesthj-168	58	59	iv	iv	NUM
anesthj-168	58	60	yielded	yield	VERB
anesthj-168	58	61	an	an	DET
anesthj-168	58	62	immediate	immediate	ADJ
anesthj-168	58	63	increase	increase	NOUN
anesthj-168	58	64	in	in	ADP
anesthj-168	58	65	the	the	DET
anesthj-168	58	66	sbp	sbp	NOUN
anesthj-168	58	67	to	to	ADP
anesthj-168	58	68	100	100	NUM
anesthj-168	58	69	mmhg.5	mmhg.5	NOUN
anesthj-168	58	70	the	the	DET
anesthj-168	58	71	operation	operation	NOUN
anesthj-168	58	72	was	be	AUX
anesthj-168	58	73	completed	complete	VERB
anesthj-168	58	74	,	,	PUNCT
anesthj-168	58	75	and	and	CCONJ
anesthj-168	58	76	the	the	DET
anesthj-168	58	77	patient	patient	NOUN
anesthj-168	58	78	was	be	AUX
anesthj-168	58	79	transferred	transfer	VERB
anesthj-168	58	80	to	to	ADP
anesthj-168	58	81	the	the	DET
anesthj-168	58	82	icu	icu	PROPN
anesthj-168	58	83	in	in	ADP
anesthj-168	58	84	stable	stable	ADJ
anesthj-168	58	85	condition	condition	NOUN
anesthj-168	58	86	and	and	CCONJ
anesthj-168	58	87	discharged	discharge	VERB
anesthj-168	58	88	5	5	NUM
anesthj-168	58	89	days	day	NOUN
anesthj-168	58	90	later5	later5	NOUN