id	sid	tid	token	lemma	pos
anesthj-33	1	1	anesthesia	anesthesia	PROPN
anesthj-33	1	2	ejournal	ejournal	ADJ
anesthj-33	1	3	volume	volume	NOUN
anesthj-33	1	4	4	4	NUM
anesthj-33	1	5	issue	issue	NOUN
anesthj-33	1	6	1	1	NUM
anesthj-33	1	7	2016	2016	NUM
anesthj-33	1	8	aej	aej	PROPN
anesthj-33	1	9	educated	educate	VERB
anesthj-33	1	10	hand	hand	NOUN
anesthj-33	1	11	publishing	publish	VERB
anesthj-33	1	12	llc	llc	PROPN
anesthj-33	1	13	“	"	PUNCT
anesthj-33	1	14	the	the	DET
anesthj-33	1	15	science	science	NOUN
anesthj-33	1	16	behind	behind	ADP
anesthj-33	1	17	the	the	DET
anesthj-33	1	18	art	art	NOUN
anesthj-33	1	19	”	"	PUNCT
anesthj-33	1	20	anesthesia	anesthesia	PROPN
anesthj-33	1	21	ejournal	ejournal	PROPN
anesthj-33	1	22	online	online	PROPN
anesthj-33	1	23	issn	issn	PROPN
anesthj-33	1	24	2333	2333	NUM
anesthj-33	1	25	-	-	SYM
anesthj-33	1	26	2611	2611	NUM
anesthj-33	1	27	page	page	NOUN
anesthj-33	1	28	20	20	NUM
anesthj-33	1	29	anesthetic	anesthetic	ADJ
anesthj-33	1	30	management	management	NOUN
anesthj-33	1	31	of	of	ADP
anesthj-33	1	32	a	a	DET
anesthj-33	1	33	patient	patient	NOUN
anesthj-33	1	34	with	with	ADP
anesthj-33	1	35	mitochondrial	mitochondrial	ADJ
anesthj-33	1	36	encephalopathy	encephalopathy	NOUN
anesthj-33	1	37	,	,	PUNCT
anesthj-33	1	38	lactic	lactic	ADJ
anesthj-33	1	39	acidosis	acidosis	NOUN
anesthj-33	1	40	,	,	PUNCT
anesthj-33	1	41	and	and	CCONJ
anesthj-33	1	42	stroke	stroke	NOUN
anesthj-33	1	43	-	-	PUNCT
anesthj-33	1	44	like	like	ADJ
anesthj-33	1	45	symptoms	symptom	NOUN
anesthj-33	1	46	(	(	PUNCT
anesthj-33	1	47	melas	mela	NOUN
anesthj-33	1	48	):	):	PUNCT
anesthj-33	1	49	a	a	DET
anesthj-33	1	50	case	case	NOUN
anesthj-33	1	51	study	study	NOUN
anesthj-33	1	52	annabelle	annabelle	PROPN
anesthj-33	1	53	flanagan	flanagan	PROPN
anesthj-33	1	54	dnp	dnp	PROPN
anesthj-33	1	55	,	,	PUNCT
anesthj-33	1	56	crna	crna	PROPN
anesthj-33	1	57	affiliation	affiliation	NOUN
anesthj-33	1	58	:	:	PUNCT
anesthj-33	1	59	texas	texas	PROPN
anesthj-33	1	60	christian	christian	PROPN
anesthj-33	1	61	university	university	PROPN
anesthj-33	1	62	,	,	PUNCT
anesthj-33	1	63	email	email	NOUN
anesthj-33	1	64	:	:	PUNCT
anesthj-33	1	65	annabelle.h.flanagan@gmail.com	annabelle.h.flanagan@gmail.com	PROPN
anesthj-33	1	66	dennis	dennis	PROPN
anesthj-33	1	67	cheek	cheek	PROPN
anesthj-33	1	68	phd	phd	PROPN
anesthj-33	1	69	,	,	PUNCT
anesthj-33	1	70	rn	rn	PROPN
anesthj-33	1	71	affiliation	affiliation	NOUN
anesthj-33	1	72	:	:	PUNCT
anesthj-33	1	73	texas	texas	PROPN
anesthj-33	1	74	christian	christian	PROPN
anesthj-33	1	75	university	university	PROPN
anesthj-33	1	76	,	,	PUNCT
anesthj-33	1	77	email	email	NOUN
anesthj-33	1	78	:	:	PUNCT
anesthj-33	1	79	d.cheek@tcu.edu	d.cheek@tcu.edu	PROPN
anesthj-33	1	80	funding	funding	PROPN
anesthj-33	1	81	/	/	SYM
anesthj-33	1	82	conflict	conflict	NOUN
anesthj-33	1	83	of	of	ADP
anesthj-33	1	84	interest	interest	NOUN
anesthj-33	1	85	disclosure	disclosure	NOUN
anesthj-33	1	86	:	:	PUNCT
anesthj-33	1	87	none	none	NOUN
anesthj-33	1	88	keywords	keyword	VERB
anesthj-33	1	89	:	:	PUNCT
anesthj-33	2	1	melas	mela	NOUN
anesthj-33	2	2	,	,	PUNCT
anesthj-33	2	3	mitochondrial	mitochondrial	ADJ
anesthj-33	2	4	disorders	disorder	NOUN
anesthj-33	2	5	,	,	PUNCT
anesthj-33	2	6	anesthetic	anesthetic	ADJ
anesthj-33	2	7	management	management	NOUN
anesthj-33	2	8	,	,	PUNCT
anesthj-33	2	9	mitochondrial	mitochondrial	ADJ
anesthj-33	2	10	myopathy	myopathy	ADJ
anesthj-33	2	11	introduction	introduction	NOUN
anesthj-33	2	12	mitochondrial	mitochondrial	ADJ
anesthj-33	2	13	myopathies	myopathy	NOUN
anesthj-33	2	14	(	(	PUNCT
anesthj-33	2	15	mms	mms	NOUN
anesthj-33	2	16	)	)	PUNCT
anesthj-33	2	17	represent	represent	VERB
anesthj-33	2	18	a	a	DET
anesthj-33	2	19	wide	wide	ADJ
anesthj-33	2	20	range	range	NOUN
anesthj-33	2	21	of	of	ADP
anesthj-33	2	22	defects	defect	NOUN
anesthj-33	2	23	in	in	ADP
anesthj-33	2	24	the	the	DET
anesthj-33	2	25	mitochondria.1	mitochondria.1	PROPN
anesthj-33	2	26	mitochondrial	mitochondrial	ADJ
anesthj-33	2	27	encephalopathy	encephalopathy	NOUN
anesthj-33	2	28	,	,	PUNCT
anesthj-33	2	29	lactic	lactic	ADJ
anesthj-33	2	30	acidosis	acidosis	NOUN
anesthj-33	2	31	,	,	PUNCT
anesthj-33	2	32	and	and	CCONJ
anesthj-33	2	33	stroke	stroke	NOUN
anesthj-33	2	34	-	-	PUNCT
anesthj-33	2	35	like	like	ADJ
anesthj-33	2	36	symptoms	symptom	NOUN
anesthj-33	2	37	(	(	PUNCT
anesthj-33	2	38	melas	mela	NOUN
anesthj-33	2	39	)	)	PUNCT
anesthj-33	2	40	syndrome	syndrome	NOUN
anesthj-33	2	41	is	be	AUX
anesthj-33	2	42	a	a	DET
anesthj-33	2	43	type	type	NOUN
anesthj-33	2	44	of	of	ADP
anesthj-33	2	45	mitochondrial	mitochondrial	ADJ
anesthj-33	2	46	disease	disease	NOUN
anesthj-33	2	47	that	that	PRON
anesthj-33	2	48	is	be	AUX
anesthj-33	2	49	systemic	systemic	ADJ
anesthj-33	2	50	in	in	ADP
anesthj-33	2	51	nature.2	nature.2	PROPN
anesthj-33	2	52	this	this	PRON
anesthj-33	2	53	is	be	AUX
anesthj-33	2	54	because	because	SCONJ
anesthj-33	2	55	of	of	ADP
anesthj-33	2	56	the	the	DET
anesthj-33	2	57	multiple	multiple	ADJ
anesthj-33	2	58	functions	function	NOUN
anesthj-33	2	59	mitochondria	mitochondria	PROPN
anesthj-33	2	60	serve	serve	VERB
anesthj-33	2	61	in	in	ADP
anesthj-33	2	62	oxidative	oxidative	ADJ
anesthj-33	2	63	phosphorylation	phosphorylation	NOUN
anesthj-33	2	64	.	.	PUNCT
anesthj-33	3	1	melas	mela	NOUN
anesthj-33	3	2	has	have	AUX
anesthj-33	3	3	been	be	AUX
anesthj-33	3	4	speculated	speculate	VERB
anesthj-33	3	5	to	to	PART
anesthj-33	3	6	affect	affect	VERB
anesthj-33	3	7	respiratory	respiratory	ADJ
anesthj-33	3	8	enzyme	enzyme	NOUN
anesthj-33	3	9	complexes	complex	NOUN
anesthj-33	3	10	i	i	PRON
anesthj-33	3	11	and	and	CCONJ
anesthj-33	3	12	iv	iv	NUM
anesthj-33	3	13	,	,	PUNCT
anesthj-33	3	14	which	which	PRON
anesthj-33	3	15	are	be	AUX
anesthj-33	3	16	essential	essential	ADJ
anesthj-33	3	17	in	in	ADP
anesthj-33	3	18	converting	convert	VERB
anesthj-33	3	19	substrates	substrate	NOUN
anesthj-33	3	20	from	from	ADP
anesthj-33	3	21	glycolysis	glycolysis	NOUN
anesthj-33	3	22	,	,	PUNCT
anesthj-33	3	23	fatty	fatty	NOUN
anesthj-33	3	24	acid	acid	NOUN
anesthj-33	3	25	oxidation	oxidation	NOUN
anesthj-33	3	26	,	,	PUNCT
anesthj-33	3	27	and	and	CCONJ
anesthj-33	3	28	the	the	DET
anesthj-33	3	29	tricarboxylic	tricarboxylic	ADJ
anesthj-33	3	30	acid	acid	NOUN
anesthj-33	3	31	cycle	cycle	NOUN
anesthj-33	3	32	to	to	AUX
anesthj-33	3	33	atp.1,3	atp.1,3	VERB
anesthj-33	3	34	this	this	DET
anesthj-33	3	35	disease	disease	NOUN
anesthj-33	3	36	is	be	AUX
anesthj-33	3	37	thought	think	VERB
anesthj-33	3	38	to	to	PART
anesthj-33	3	39	pass	pass	VERB
anesthj-33	3	40	maternally	maternally	ADV
anesthj-33	3	41	and	and	CCONJ
anesthj-33	3	42	to	to	PART
anesthj-33	3	43	result	result	VERB
anesthj-33	3	44	from	from	ADP
anesthj-33	3	45	a	a	DET
anesthj-33	3	46	mutation	mutation	NOUN
anesthj-33	3	47	in	in	ADP
anesthj-33	3	48	mitochondrial	mitochondrial	ADJ
anesthj-33	3	49	dna.1,2	dna.1,2	PROPN
anesthj-33	3	50	because	because	SCONJ
anesthj-33	3	51	melas	mela	NOUN
anesthj-33	3	52	involves	involve	VERB
anesthj-33	3	53	a	a	DET
anesthj-33	3	54	mitochondrial	mitochondrial	ADJ
anesthj-33	3	55	defect	defect	NOUN
anesthj-33	3	56	in	in	ADP
anesthj-33	3	57	aerobic	aerobic	ADJ
anesthj-33	3	58	metabolism	metabolism	NOUN
anesthj-33	3	59	,	,	PUNCT
anesthj-33	3	60	the	the	DET
anesthj-33	3	61	disease	disease	NOUN
anesthj-33	3	62	has	have	VERB
anesthj-33	3	63	implications	implication	NOUN
anesthj-33	3	64	for	for	ADP
anesthj-33	3	65	anesthesia	anesthesia	NOUN
anesthj-33	3	66	management	management	NOUN
anesthj-33	3	67	.	.	PUNCT
anesthj-33	4	1	anesthetic	anesthetic	ADJ
anesthj-33	4	2	medications	medication	NOUN
anesthj-33	4	3	,	,	PUNCT
anesthj-33	4	4	surgery	surgery	NOUN
anesthj-33	4	5	itself	itself	PRON
anesthj-33	4	6	,	,	PUNCT
anesthj-33	4	7	and	and	CCONJ
anesthj-33	4	8	fasting	fast	VERB
anesthj-33	4	9	in	in	ADP
anesthj-33	4	10	preparation	preparation	NOUN
anesthj-33	4	11	for	for	ADP
anesthj-33	4	12	surgery	surgery	NOUN
anesthj-33	4	13	can	can	AUX
anesthj-33	4	14	all	all	PRON
anesthj-33	4	15	increase	increase	VERB
anesthj-33	4	16	the	the	DET
anesthj-33	4	17	metabolic	metabolic	NOUN
anesthj-33	4	18	burden	burden	NOUN
anesthj-33	4	19	,	,	PUNCT
anesthj-33	4	20	leading	lead	VERB
anesthj-33	4	21	to	to	ADP
anesthj-33	4	22	possible	possible	ADJ
anesthj-33	4	23	exacerbations	exacerbation	NOUN
anesthj-33	4	24	in	in	ADP
anesthj-33	4	25	tissues	tissue	NOUN
anesthj-33	4	26	dependent	dependent	ADJ
anesthj-33	4	27	on	on	ADP
anesthj-33	4	28	large	large	ADJ
anesthj-33	4	29	amounts	amount	NOUN
anesthj-33	4	30	of	of	ADP
anesthj-33	4	31	oxygen	oxygen	NOUN
anesthj-33	4	32	,	,	PUNCT
anesthj-33	4	33	such	such	ADJ
anesthj-33	4	34	as	as	ADP
anesthj-33	4	35	the	the	DET
anesthj-33	4	36	heart	heart	NOUN
anesthj-33	4	37	,	,	PUNCT
anesthj-33	4	38	muscle	muscle	NOUN
anesthj-33	4	39	,	,	PUNCT
anesthj-33	4	40	and	and	CCONJ
anesthj-33	4	41	central	central	ADJ
anesthj-33	4	42	nervous	nervous	ADJ
anesthj-33	4	43	system.4,5	system.4,5	ADJ
anesthj-33	4	44	mms	mms	NOUN
anesthj-33	4	45	have	have	AUX
anesthj-33	4	46	also	also	ADV
anesthj-33	4	47	been	be	AUX
anesthj-33	4	48	speculatively	speculatively	ADV
anesthj-33	4	49	linked	link	VERB
anesthj-33	4	50	to	to	ADP
anesthj-33	4	51	malignant	malignant	ADJ
anesthj-33	4	52	hyperthermia	hyperthermia	NOUN
anesthj-33	4	53	owing	owe	VERB
anesthj-33	4	54	to	to	ADP
anesthj-33	4	55	the	the	DET
anesthj-33	4	56	similar	similar	ADJ
anesthj-33	4	57	presentation	presentation	NOUN
anesthj-33	4	58	of	of	ADP
anesthj-33	4	59	symptoms	symptom	NOUN
anesthj-33	4	60	.	.	PUNCT
anesthj-33	5	1	controversy	controversy	NOUN
anesthj-33	5	2	exists	exist	VERB
anesthj-33	5	3	,	,	PUNCT
anesthj-33	5	4	however	however	ADV
anesthj-33	5	5	,	,	PUNCT
anesthj-33	5	6	over	over	ADP
anesthj-33	5	7	whether	whether	SCONJ
anesthj-33	5	8	anesthetic	anesthetic	ADJ
anesthj-33	5	9	management	management	NOUN
anesthj-33	5	10	should	should	AUX
anesthj-33	5	11	be	be	AUX
anesthj-33	5	12	based	base	VERB
anesthj-33	5	13	on	on	ADP
anesthj-33	5	14	concerns	concern	NOUN
anesthj-33	5	15	to	to	PART
anesthj-33	5	16	avoid	avoid	VERB
anesthj-33	5	17	malignant	malignant	ADJ
anesthj-33	5	18	hyperthermia	hyperthermia	NOUN
anesthj-33	5	19	triggers	trigger	NOUN
anesthj-33	5	20	.	.	PUNCT
anesthj-33	6	1	abstract	abstract	ADJ
anesthj-33	6	2	mitochondrial	mitochondrial	ADJ
anesthj-33	6	3	encephalopathy	encephalopathy	NOUN
anesthj-33	6	4	,	,	PUNCT
anesthj-33	6	5	lactic	lactic	ADJ
anesthj-33	6	6	acidosis	acidosis	NOUN
anesthj-33	6	7	,	,	PUNCT
anesthj-33	6	8	stroke	stroke	NOUN
anesthj-33	6	9	-	-	PUNCT
anesthj-33	6	10	like	like	ADJ
anesthj-33	6	11	symptoms	symptom	NOUN
anesthj-33	6	12	(	(	PUNCT
anesthj-33	6	13	melas	mela	NOUN
anesthj-33	6	14	)	)	PUNCT
anesthj-33	6	15	syndrome	syndrome	NOUN
anesthj-33	6	16	is	be	AUX
anesthj-33	6	17	a	a	DET
anesthj-33	6	18	specific	specific	ADJ
anesthj-33	6	19	mitochondrial	mitochondrial	ADJ
anesthj-33	6	20	myopathy	myopathy	NOUN
anesthj-33	6	21	that	that	PRON
anesthj-33	6	22	results	result	VERB
anesthj-33	6	23	in	in	ADP
anesthj-33	6	24	defects	defect	NOUN
anesthj-33	6	25	in	in	ADP
anesthj-33	6	26	respiratory	respiratory	ADJ
anesthj-33	6	27	enzyme	enzyme	NOUN
anesthj-33	6	28	complexes	complex	NOUN
anesthj-33	6	29	i	i	PRON
anesthj-33	6	30	and	and	CCONJ
anesthj-33	6	31	iv	iv	X
anesthj-33	6	32	.	.	PUNCT
anesthj-33	7	1	this	this	PRON
anesthj-33	7	2	ultimately	ultimately	ADV
anesthj-33	7	3	causes	cause	VERB
anesthj-33	7	4	defects	defect	NOUN
anesthj-33	7	5	in	in	ADP
anesthj-33	7	6	aerobic	aerobic	ADJ
anesthj-33	7	7	metabolism	metabolism	NOUN
anesthj-33	7	8	,	,	PUNCT
anesthj-33	7	9	especially	especially	ADV
anesthj-33	7	10	in	in	ADP
anesthj-33	7	11	high	high	ADJ
anesthj-33	7	12	-	-	PUNCT
anesthj-33	7	13	energy	energy	NOUN
anesthj-33	7	14	-	-	PUNCT
anesthj-33	7	15	requiring	require	VERB
anesthj-33	7	16	organs	organ	NOUN
anesthj-33	7	17	,	,	PUNCT
anesthj-33	7	18	leading	lead	VERB
anesthj-33	7	19	to	to	ADP
anesthj-33	7	20	an	an	DET
anesthj-33	7	21	obvious	obvious	ADJ
anesthj-33	7	22	concern	concern	NOUN
anesthj-33	7	23	with	with	ADP
anesthj-33	7	24	anesthetic	anesthetic	ADJ
anesthj-33	7	25	management	management	NOUN
anesthj-33	7	26	.	.	PUNCT
anesthj-33	8	1	some	some	DET
anesthj-33	8	2	mitochondrial	mitochondrial	ADJ
anesthj-33	8	3	myopathies	myopathy	NOUN
anesthj-33	8	4	have	have	VERB
anesthj-33	8	5	speculative	speculative	ADJ
anesthj-33	8	6	linkages	linkage	NOUN
anesthj-33	8	7	to	to	ADP
anesthj-33	8	8	malignant	malignant	ADJ
anesthj-33	8	9	hyperthermia	hyperthermia	NOUN
anesthj-33	8	10	.	.	PUNCT
anesthj-33	9	1	this	this	DET
anesthj-33	9	2	case	case	NOUN
anesthj-33	9	3	report	report	NOUN
anesthj-33	9	4	examines	examine	VERB
anesthj-33	9	5	the	the	DET
anesthj-33	9	6	anesthetic	anesthetic	ADJ
anesthj-33	9	7	implications	implication	NOUN
anesthj-33	9	8	for	for	ADP
anesthj-33	9	9	a	a	DET
anesthj-33	9	10	patient	patient	NOUN
anesthj-33	9	11	with	with	ADP
anesthj-33	9	12	melas	mela	NOUN
anesthj-33	9	13	.	.	PUNCT
anesthj-33	10	1	a	a	DET
anesthj-33	10	2	39	39	NUM
anesthj-33	10	3	-	-	PUNCT
anesthj-33	10	4	year	year	NOUN
anesthj-33	10	5	-	-	PUNCT
anesthj-33	10	6	old	old	ADJ
anesthj-33	10	7	man	man	NOUN
anesthj-33	10	8	with	with	ADP
anesthj-33	10	9	melas	mela	NOUN
anesthj-33	10	10	underwent	undergo	VERB
anesthj-33	10	11	a	a	DET
anesthj-33	10	12	right	right	ADJ
anesthj-33	10	13	hip	hip	NOUN
anesthj-33	10	14	fracture	fracture	NOUN
anesthj-33	10	15	pinning	pinning	NOUN
anesthj-33	10	16	.	.	PUNCT
anesthj-33	11	1	the	the	DET
anesthj-33	11	2	patient	patient	NOUN
anesthj-33	11	3	was	be	AUX
anesthj-33	11	4	successfully	successfully	ADV
anesthj-33	11	5	managed	manage	VERB
anesthj-33	11	6	with	with	ADP
anesthj-33	11	7	a	a	DET
anesthj-33	11	8	general	general	ADJ
anesthj-33	11	9	endotracheal	endotracheal	NOUN
anesthj-33	11	10	anesthetic	anesthetic	NOUN
anesthj-33	11	11	using	use	VERB
anesthj-33	11	12	a	a	DET
anesthj-33	11	13	propofol	propofol	ADJ
anesthj-33	11	14	infusion	infusion	NOUN
anesthj-33	11	15	and	and	CCONJ
anesthj-33	11	16	<	<	X
anesthj-33	11	17	1	1	NUM
anesthj-33	11	18	minimum	minimum	ADJ
anesthj-33	11	19	alveolar	alveolar	ADJ
anesthj-33	11	20	concentration	concentration	NOUN
anesthj-33	11	21	of	of	ADP
anesthj-33	11	22	sevoflurane	sevoflurane	ADJ
anesthj-33	11	23	gas	gas	NOUN
anesthj-33	11	24	.	.	PUNCT
anesthj-33	12	1	the	the	DET
anesthj-33	12	2	patient	patient	NOUN
anesthj-33	12	3	was	be	AUX
anesthj-33	12	4	extubated	extubate	VERB
anesthj-33	12	5	without	without	ADP
anesthj-33	12	6	complications	complication	NOUN
anesthj-33	12	7	.	.	PUNCT
anesthj-33	13	1	anesthetic	anesthetic	ADJ
anesthj-33	13	2	implications	implication	NOUN
anesthj-33	13	3	for	for	ADP
anesthj-33	13	4	the	the	DET
anesthj-33	13	5	management	management	NOUN
anesthj-33	13	6	of	of	ADP
anesthj-33	13	7	patients	patient	NOUN
anesthj-33	13	8	with	with	ADP
anesthj-33	13	9	melas	mela	NOUN
anesthj-33	13	10	include	include	VERB
anesthj-33	13	11	a	a	DET
anesthj-33	13	12	tailored	tailor	VERB
anesthj-33	13	13	preoperative	preoperative	ADJ
anesthj-33	13	14	assessment	assessment	NOUN
anesthj-33	13	15	because	because	SCONJ
anesthj-33	13	16	of	of	ADP
anesthj-33	13	17	the	the	DET
anesthj-33	13	18	different	different	ADJ
anesthj-33	13	19	phenotypical	phenotypical	ADJ
anesthj-33	13	20	presentations	presentation	NOUN
anesthj-33	13	21	of	of	ADP
anesthj-33	13	22	mitochondrial	mitochondrial	ADJ
anesthj-33	13	23	diseases	disease	NOUN
anesthj-33	13	24	.	.	PUNCT
anesthj-33	14	1	the	the	DET
anesthj-33	14	2	metabolic	metabolic	NOUN
anesthj-33	14	3	burden	burden	NOUN
anesthj-33	14	4	in	in	ADP
anesthj-33	14	5	melas	mela	NOUN
anesthj-33	14	6	patients	patient	NOUN
anesthj-33	14	7	can	can	AUX
anesthj-33	14	8	be	be	AUX
anesthj-33	14	9	reduced	reduce	VERB
anesthj-33	14	10	by	by	ADP
anesthj-33	14	11	avoidance	avoidance	NOUN
anesthj-33	14	12	of	of	ADP
anesthj-33	14	13	the	the	DET
anesthj-33	14	14	following	following	NOUN
anesthj-33	14	15	:	:	PUNCT
anesthj-33	14	16	lactate	lactate	NOUN
anesthj-33	14	17	in	in	ADP
anesthj-33	14	18	intravenous	intravenous	ADJ
anesthj-33	14	19	fluids	fluid	NOUN
anesthj-33	14	20	,	,	PUNCT
anesthj-33	14	21	hypothermia	hypothermia	NOUN
anesthj-33	14	22	,	,	PUNCT
anesthj-33	14	23	prolonged	prolonged	ADJ
anesthj-33	14	24	fasting	fasting	NOUN
anesthj-33	14	25	,	,	PUNCT
anesthj-33	14	26	and	and	CCONJ
anesthj-33	14	27	postoperative	postoperative	ADJ
anesthj-33	14	28	nausea	nausea	NOUN
anesthj-33	14	29	vomiting	vomiting	NOUN
anesthj-33	14	30	.	.	PUNCT
anesthj-33	15	1	varied	varied	ADJ
anesthj-33	15	2	anesthetic	anesthetic	ADJ
anesthj-33	15	3	techniques	technique	NOUN
anesthj-33	15	4	have	have	AUX
anesthj-33	15	5	been	be	AUX
anesthj-33	15	6	documented	document	VERB
anesthj-33	15	7	in	in	ADP
anesthj-33	15	8	multiple	multiple	ADJ
anesthj-33	15	9	case	case	NOUN
anesthj-33	15	10	reports	report	VERB
anesthj-33	15	11	.	.	PUNCT
anesthj-33	16	1	careful	careful	ADJ
anesthj-33	16	2	titration	titration	NOUN
anesthj-33	16	3	of	of	ADP
anesthj-33	16	4	muscle	muscle	NOUN
anesthj-33	16	5	relaxants	relaxant	NOUN
anesthj-33	16	6	and	and	CCONJ
anesthj-33	16	7	opioids	opioid	NOUN
anesthj-33	16	8	is	be	AUX
anesthj-33	16	9	paramount	paramount	ADJ
anesthj-33	16	10	to	to	PART
anesthj-33	16	11	prevent	prevent	VERB
anesthj-33	16	12	postoperative	postoperative	ADJ
anesthj-33	16	13	respiratory	respiratory	ADJ
anesthj-33	16	14	failure	failure	NOUN
anesthj-33	16	15	.	.	PUNCT
anesthj-33	17	1	according	accord	VERB
anesthj-33	17	2	to	to	ADP
anesthj-33	17	3	the	the	DET
anesthj-33	17	4	malignant	malignant	ADJ
anesthj-33	17	5	hyperthermia	hyperthermia	NOUN
anesthj-33	17	6	association	association	NOUN
anesthj-33	17	7	of	of	ADP
anesthj-33	17	8	the	the	DET
anesthj-33	17	9	united	united	PROPN
anesthj-33	17	10	states	states	PROPN
anesthj-33	17	11	,	,	PUNCT
anesthj-33	17	12	avoidance	avoidance	NOUN
anesthj-33	17	13	of	of	ADP
anesthj-33	17	14	volatile	volatile	ADJ
anesthj-33	17	15	anesthetics	anesthetic	NOUN
anesthj-33	17	16	is	be	AUX
anesthj-33	17	17	not	not	PART
anesthj-33	17	18	necessary	necessary	ADJ
anesthj-33	17	19	in	in	ADP
anesthj-33	17	20	patients	patient	NOUN
anesthj-33	17	21	with	with	ADP
anesthj-33	17	22	mitochondrial	mitochondrial	ADJ
anesthj-33	17	23	myopathy	myopathy	NOUN
anesthj-33	17	24	.	.	PUNCT
anesthj-33	18	1	mailto:annabelle.h.flanagan@gmail.com	mailto:annabelle.h.flanagan@gmail.com	X
anesthj-33	19	1	mailto:d.cheek@tcu.edu	mailto:d.cheek@tcu.edu	PROPN
anesthj-33	19	2	anesthesia	anesthesia	PROPN
anesthj-33	19	3	ejournal	ejournal	PROPN
anesthj-33	19	4	www.anesthesiaejournal.com	www.anesthesiaejournal.com	PROPN
anesthj-33	19	5	volume	volume	NOUN
anesthj-33	19	6	4	4	NUM
anesthj-33	19	7	issue	issue	NOUN
anesthj-33	19	8	1	1	NUM
anesthj-33	19	9	2016	2016	NUM
anesthj-33	19	10	page	page	NOUN
anesthj-33	19	11	21	21	NUM
anesthj-33	19	12	case	case	NOUN
anesthj-33	19	13	summary	summary	VERB
anesthj-33	19	14	a	a	DET
anesthj-33	19	15	39	39	NUM
anesthj-33	19	16	-	-	PUNCT
anesthj-33	19	17	year	year	NOUN
anesthj-33	19	18	-	-	PUNCT
anesthj-33	19	19	old	old	ADJ
anesthj-33	19	20	hispanic	hispanic	ADJ
anesthj-33	19	21	male	male	NOUN
anesthj-33	19	22	,	,	PUNCT
anesthj-33	19	23	with	with	ADP
anesthj-33	19	24	a	a	DET
anesthj-33	19	25	weight	weight	NOUN
anesthj-33	19	26	of	of	ADP
anesthj-33	19	27	49	49	NUM
anesthj-33	19	28	kg	kg	NOUN
anesthj-33	19	29	and	and	CCONJ
anesthj-33	19	30	a	a	DET
anesthj-33	19	31	height	height	NOUN
anesthj-33	19	32	of	of	ADP
anesthj-33	19	33	157	157	NUM
anesthj-33	19	34	cm	cm	NOUN
anesthj-33	19	35	,	,	PUNCT
anesthj-33	19	36	presented	present	VERB
anesthj-33	19	37	with	with	ADP
anesthj-33	19	38	a	a	DET
anesthj-33	19	39	right	right	ADJ
anesthj-33	19	40	hip	hip	NOUN
anesthj-33	19	41	fracture	fracture	NOUN
anesthj-33	19	42	.	.	PUNCT
anesthj-33	20	1	the	the	DET
anesthj-33	20	2	surgical	surgical	ADJ
anesthj-33	20	3	procedure	procedure	NOUN
anesthj-33	20	4	planned	plan	VERB
anesthj-33	20	5	for	for	ADP
anesthj-33	20	6	this	this	DET
anesthj-33	20	7	patient	patient	NOUN
anesthj-33	20	8	was	be	AUX
anesthj-33	20	9	a	a	DET
anesthj-33	20	10	right	right	ADJ
anesthj-33	20	11	hip	hip	NOUN
anesthj-33	20	12	fracture	fracture	NOUN
anesthj-33	20	13	pinning	pinning	NOUN
anesthj-33	20	14	.	.	PUNCT
anesthj-33	21	1	his	his	PRON
anesthj-33	21	2	previous	previous	ADJ
anesthj-33	21	3	medical	medical	ADJ
anesthj-33	21	4	history	history	NOUN
anesthj-33	21	5	included	include	VERB
anesthj-33	21	6	a	a	DET
anesthj-33	21	7	cerebrovascular	cerebrovascular	ADJ
anesthj-33	21	8	accident	accident	NOUN
anesthj-33	21	9	in	in	ADP
anesthj-33	21	10	2008	2008	NUM
anesthj-33	21	11	apparently	apparently	ADV
anesthj-33	21	12	while	while	SCONJ
anesthj-33	21	13	operating	operate	VERB
anesthj-33	21	14	a	a	DET
anesthj-33	21	15	motor	motor	NOUN
anesthj-33	21	16	vehicle	vehicle	NOUN
anesthj-33	21	17	.	.	PUNCT
anesthj-33	22	1	immediately	immediately	ADV
anesthj-33	22	2	before	before	ADP
anesthj-33	22	3	this	this	DET
anesthj-33	22	4	motor	motor	NOUN
anesthj-33	22	5	vehicle	vehicle	NOUN
anesthj-33	22	6	accident	accident	NOUN
anesthj-33	22	7	,	,	PUNCT
anesthj-33	22	8	the	the	DET
anesthj-33	22	9	patient	patient	NOUN
anesthj-33	22	10	had	have	VERB
anesthj-33	22	11	blurry	blurry	ADJ
anesthj-33	22	12	vision	vision	NOUN
anesthj-33	22	13	and	and	CCONJ
anesthj-33	22	14	a	a	DET
anesthj-33	22	15	subsequent	subsequent	ADJ
anesthj-33	22	16	seizure	seizure	NOUN
anesthj-33	22	17	.	.	PUNCT
anesthj-33	23	1	upon	upon	SCONJ
anesthj-33	23	2	admission	admission	NOUN
anesthj-33	23	3	to	to	ADP
anesthj-33	23	4	the	the	DET
anesthj-33	23	5	hospital	hospital	NOUN
anesthj-33	23	6	after	after	ADP
anesthj-33	23	7	the	the	DET
anesthj-33	23	8	motor	motor	NOUN
anesthj-33	23	9	vehicle	vehicle	NOUN
anesthj-33	23	10	accident	accident	NOUN
anesthj-33	23	11	,	,	PUNCT
anesthj-33	23	12	a	a	DET
anesthj-33	23	13	muscle	muscle	NOUN
anesthj-33	23	14	biopsy	biopsy	NOUN
anesthj-33	23	15	was	be	AUX
anesthj-33	23	16	performed	perform	VERB
anesthj-33	23	17	and	and	CCONJ
anesthj-33	23	18	the	the	DET
anesthj-33	23	19	myopathy	myopathy	ADJ
anesthj-33	23	20	melas	mela	NOUN
anesthj-33	23	21	was	be	AUX
anesthj-33	23	22	discovered	discover	VERB
anesthj-33	23	23	.	.	PUNCT
anesthj-33	24	1	the	the	DET
anesthj-33	24	2	patient	patient	NOUN
anesthj-33	24	3	’s	’s	PART
anesthj-33	24	4	other	other	ADJ
anesthj-33	24	5	medical	medical	ADJ
anesthj-33	24	6	conditions	condition	NOUN
anesthj-33	24	7	included	include	VERB
anesthj-33	24	8	hearing	hear	VERB
anesthj-33	24	9	loss	loss	NOUN
anesthj-33	24	10	,	,	PUNCT
anesthj-33	24	11	diabetes	diabetes	NOUN
anesthj-33	24	12	,	,	PUNCT
anesthj-33	24	13	and	and	CCONJ
anesthj-33	24	14	an	an	DET
anesthj-33	24	15	unsteady	unsteady	ADJ
anesthj-33	24	16	gait	gait	NOUN
anesthj-33	24	17	related	relate	VERB
anesthj-33	24	18	to	to	ADP
anesthj-33	24	19	the	the	DET
anesthj-33	24	20	motor	motor	NOUN
anesthj-33	24	21	vehicle	vehicle	NOUN
anesthj-33	24	22	accident	accident	NOUN
anesthj-33	24	23	.	.	PUNCT
anesthj-33	25	1	the	the	DET
anesthj-33	25	2	patient	patient	NOUN
anesthj-33	25	3	’s	’s	PART
anesthj-33	25	4	medications	medication	NOUN
anesthj-33	25	5	included	include	VERB
anesthj-33	25	6	aspirin	aspirin	NOUN
anesthj-33	25	7	,	,	PUNCT
anesthj-33	25	8	insulin	insulin	NOUN
anesthj-33	25	9	,	,	PUNCT
anesthj-33	25	10	pantoprazole	pantoprazole	NOUN
anesthj-33	25	11	,	,	PUNCT
anesthj-33	25	12	carbamazepine	carbamazepine	NOUN
anesthj-33	25	13	,	,	PUNCT
anesthj-33	25	14	zonisamide	zonisamide	ADV
anesthj-33	25	15	,	,	PUNCT
anesthj-33	25	16	co	co	ADJ
anesthj-33	25	17	-	-	NOUN
anesthj-33	25	18	enzyme	enzyme	ADJ
anesthj-33	25	19	q10	q10	NOUN
anesthj-33	25	20	,	,	PUNCT
anesthj-33	25	21	iron	iron	NOUN
anesthj-33	25	22	,	,	PUNCT
anesthj-33	25	23	loratadine	loratadine	NOUN
anesthj-33	25	24	,	,	PUNCT
anesthj-33	25	25	and	and	CCONJ
anesthj-33	25	26	morphine	morphine	NOUN
anesthj-33	25	27	.	.	PUNCT
anesthj-33	26	1	he	he	PRON
anesthj-33	26	2	was	be	AUX
anesthj-33	26	3	assessed	assess	VERB
anesthj-33	26	4	as	as	ADP
anesthj-33	26	5	having	have	VERB
anesthj-33	26	6	an	an	DET
anesthj-33	26	7	airway	airway	NOUN
anesthj-33	26	8	classification	classification	NOUN
anesthj-33	26	9	of	of	ADP
anesthj-33	26	10	mallampati	mallampati	PROPN
anesthj-33	26	11	ii	ii	PROPN
anesthj-33	26	12	,	,	PUNCT
anesthj-33	26	13	with	with	ADP
anesthj-33	26	14	a	a	DET
anesthj-33	26	15	4	4	NUM
anesthj-33	26	16	-	-	PUNCT
anesthj-33	26	17	fingerbreadth	fingerbreadth	NOUN
anesthj-33	26	18	oral	oral	ADJ
anesthj-33	26	19	excursion	excursion	NOUN
anesthj-33	26	20	and	and	CCONJ
anesthj-33	26	21	thyromental	thyromental	ADJ
anesthj-33	26	22	distance	distance	NOUN
anesthj-33	26	23	,	,	PUNCT
anesthj-33	26	24	normal	normal	ADJ
anesthj-33	26	25	upper	upper	ADJ
anesthj-33	26	26	and	and	CCONJ
anesthj-33	26	27	lower	low	ADJ
anesthj-33	26	28	dentition	dentition	NOUN
anesthj-33	26	29	,	,	PUNCT
anesthj-33	26	30	and	and	CCONJ
anesthj-33	26	31	normal	normal	ADJ
anesthj-33	26	32	neck	neck	NOUN
anesthj-33	26	33	extension	extension	NOUN
anesthj-33	26	34	and	and	CCONJ
anesthj-33	26	35	flexion	flexion	NOUN
anesthj-33	26	36	.	.	PUNCT
anesthj-33	27	1	he	he	PRON
anesthj-33	27	2	had	have	VERB
anesthj-33	27	3	no	no	DET
anesthj-33	27	4	known	know	VERB
anesthj-33	27	5	allergies	allergy	NOUN
anesthj-33	27	6	to	to	ADP
anesthj-33	27	7	food	food	NOUN
anesthj-33	27	8	or	or	CCONJ
anesthj-33	27	9	drugs	drug	NOUN
anesthj-33	27	10	.	.	PUNCT
anesthj-33	28	1	a	a	DET
anesthj-33	28	2	review	review	NOUN
anesthj-33	28	3	of	of	ADP
anesthj-33	28	4	his	his	PRON
anesthj-33	28	5	symptoms	symptom	NOUN
anesthj-33	28	6	was	be	AUX
anesthj-33	28	7	essentially	essentially	ADV
anesthj-33	28	8	negative	negative	ADJ
anesthj-33	28	9	.	.	PUNCT
anesthj-33	29	1	the	the	DET
anesthj-33	29	2	results	result	NOUN
anesthj-33	29	3	of	of	ADP
anesthj-33	29	4	his	his	PRON
anesthj-33	29	5	physical	physical	ADJ
anesthj-33	29	6	exam	exam	NOUN
anesthj-33	29	7	were	be	AUX
anesthj-33	29	8	unremarkable	unremarkable	ADJ
anesthj-33	29	9	other	other	ADJ
anesthj-33	29	10	than	than	ADP
anesthj-33	29	11	a	a	DET
anesthj-33	29	12	foley	foley	ADJ
anesthj-33	29	13	catheter	catheter	NOUN
anesthj-33	29	14	that	that	PRON
anesthj-33	29	15	was	be	AUX
anesthj-33	29	16	in	in	ADP
anesthj-33	29	17	place	place	NOUN
anesthj-33	29	18	and	and	CCONJ
anesthj-33	29	19	musculoskeletal	musculoskeletal	ADJ
anesthj-33	29	20	decompensation	decompensation	NOUN
anesthj-33	29	21	from	from	ADP
anesthj-33	29	22	a	a	DET
anesthj-33	29	23	worsening	worsen	VERB
anesthj-33	29	24	gait	gait	NOUN
anesthj-33	29	25	with	with	ADP
anesthj-33	29	26	no	no	DET
anesthj-33	29	27	assistive	assistive	ADJ
anesthj-33	29	28	device	device	NOUN
anesthj-33	29	29	use	use	NOUN
anesthj-33	29	30	.	.	PUNCT
anesthj-33	30	1	a	a	DET
anesthj-33	30	2	22	22	NUM
anesthj-33	30	3	-	-	PUNCT
anesthj-33	30	4	guage	guage	NOUN
anesthj-33	30	5	intravenous	intravenous	ADJ
anesthj-33	30	6	catheter	catheter	NOUN
anesthj-33	30	7	was	be	AUX
anesthj-33	30	8	started	start	VERB
anesthj-33	30	9	in	in	ADP
anesthj-33	30	10	the	the	DET
anesthj-33	30	11	right	right	ADJ
anesthj-33	30	12	antecubital	antecubital	ADJ
anesthj-33	30	13	vein	vein	NOUN
anesthj-33	30	14	with	with	ADP
anesthj-33	30	15	an	an	DET
anesthj-33	30	16	infusion	infusion	NOUN
anesthj-33	30	17	of	of	ADP
anesthj-33	30	18	lactated	lactated	ADJ
anesthj-33	30	19	ringer	ringer	NOUN
anesthj-33	30	20	’s	’s	PART
anesthj-33	30	21	solution	solution	NOUN
anesthj-33	30	22	.	.	PUNCT
anesthj-33	31	1	the	the	DET
anesthj-33	31	2	serum	serum	NOUN
anesthj-33	31	3	complete	complete	ADJ
anesthj-33	31	4	blood	blood	NOUN
anesthj-33	31	5	count	count	NOUN
anesthj-33	31	6	showed	show	VERB
anesthj-33	31	7	a	a	DET
anesthj-33	31	8	slightly	slightly	ADV
anesthj-33	31	9	elevated	elevate	VERB
anesthj-33	31	10	white	white	ADJ
anesthj-33	31	11	blood	blood	NOUN
anesthj-33	31	12	cell	cell	NOUN
anesthj-33	31	13	count	count	NOUN
anesthj-33	31	14	of	of	ADP
anesthj-33	31	15	9.2	9.2	NUM
anesthj-33	31	16	and	and	CCONJ
anesthj-33	31	17	a	a	DET
anesthj-33	31	18	hemoglobin	hemoglobin	NOUN
anesthj-33	31	19	level	level	NOUN
anesthj-33	31	20	of	of	ADP
anesthj-33	31	21	11.9	11.9	NUM
anesthj-33	31	22	g	g	NOUN
anesthj-33	31	23	/	/	SYM
anesthj-33	31	24	dl	dl	PROPN
anesthj-33	31	25	.	.	PUNCT
anesthj-33	32	1	however	however	ADV
anesthj-33	32	2	,	,	PUNCT
anesthj-33	32	3	the	the	DET
anesthj-33	32	4	results	result	NOUN
anesthj-33	32	5	of	of	ADP
anesthj-33	32	6	the	the	DET
anesthj-33	32	7	basic	basic	ADJ
anesthj-33	32	8	metabolic	metabolic	NOUN
anesthj-33	32	9	panel	panel	NOUN
anesthj-33	32	10	and	and	CCONJ
anesthj-33	32	11	coagulation	coagulation	NOUN
anesthj-33	32	12	studies	study	NOUN
anesthj-33	32	13	were	be	AUX
anesthj-33	32	14	all	all	ADV
anesthj-33	32	15	within	within	ADP
anesthj-33	32	16	normal	normal	ADJ
anesthj-33	32	17	limits	limit	NOUN
anesthj-33	32	18	.	.	PUNCT
anesthj-33	33	1	his	his	PRON
anesthj-33	33	2	preoperative	preoperative	ADJ
anesthj-33	33	3	vital	vital	ADJ
anesthj-33	33	4	signs	sign	NOUN
anesthj-33	33	5	included	include	VERB
anesthj-33	33	6	blood	blood	NOUN
anesthj-33	33	7	pressure	pressure	NOUN
anesthj-33	33	8	of	of	ADP
anesthj-33	33	9	121/77	121/77	NUM
anesthj-33	33	10	mm	mm	NUM
anesthj-33	33	11	hg	hg	NOUN
anesthj-33	33	12	,	,	PUNCT
anesthj-33	33	13	heart	heart	NOUN
anesthj-33	33	14	rate	rate	NOUN
anesthj-33	33	15	of	of	ADP
anesthj-33	33	16	90	90	NUM
anesthj-33	33	17	beats	beat	NOUN
anesthj-33	33	18	per	per	ADP
anesthj-33	33	19	minute	minute	NOUN
anesthj-33	33	20	,	,	PUNCT
anesthj-33	33	21	normal	normal	ADJ
anesthj-33	33	22	sinus	sinu	NOUN
anesthj-33	33	23	rhythm	rhythm	NOUN
anesthj-33	33	24	,	,	PUNCT
anesthj-33	33	25	respiratory	respiratory	ADJ
anesthj-33	33	26	rate	rate	NOUN
anesthj-33	33	27	of	of	ADP
anesthj-33	33	28	16	16	NUM
anesthj-33	33	29	breaths	breath	NOUN
anesthj-33	33	30	per	per	ADP
anesthj-33	33	31	minute	minute	NOUN
anesthj-33	33	32	,	,	PUNCT
anesthj-33	33	33	and	and	CCONJ
anesthj-33	33	34	skin	skin	NOUN
anesthj-33	33	35	temperature	temperature	NOUN
anesthj-33	33	36	of	of	ADP
anesthj-33	33	37	37.2	37.2	NUM
anesthj-33	33	38	degrees	degree	NOUN
anesthj-33	33	39	celsius	celsius	NOUN
anesthj-33	33	40	.	.	PUNCT
anesthj-33	34	1	his	his	PRON
anesthj-33	34	2	american	american	ADJ
anesthj-33	34	3	society	society	NOUN
anesthj-33	34	4	of	of	ADP
anesthj-33	34	5	anesthesiologists	anesthesiologist	NOUN
anesthj-33	34	6	classification	classification	NOUN
anesthj-33	34	7	was	be	AUX
anesthj-33	34	8	designated	designate	VERB
anesthj-33	34	9	as	as	ADP
anesthj-33	34	10	a	a	DET
anesthj-33	34	11	iii	iii	NOUN
anesthj-33	34	12	.	.	PUNCT
anesthj-33	35	1	the	the	DET
anesthj-33	35	2	anesthetic	anesthetic	ADJ
anesthj-33	35	3	plan	plan	NOUN
anesthj-33	35	4	for	for	ADP
anesthj-33	35	5	this	this	DET
anesthj-33	35	6	patient	patient	NOUN
anesthj-33	35	7	included	include	VERB
anesthj-33	35	8	administration	administration	NOUN
anesthj-33	35	9	of	of	ADP
anesthj-33	35	10	preoperative	preoperative	ADJ
anesthj-33	35	11	medications	medication	NOUN
anesthj-33	35	12	of	of	ADP
anesthj-33	35	13	midazolam	midazolam	PROPN
anesthj-33	35	14	4	4	NUM
anesthj-33	35	15	mg	mg	NOUN
anesthj-33	35	16	and	and	CCONJ
anesthj-33	35	17	ondansetron	ondansetron	NOUN
anesthj-33	35	18	4	4	NUM
anesthj-33	35	19	mg	mg	NOUN
anesthj-33	35	20	for	for	ADP
anesthj-33	35	21	anxiolysis	anxiolysis	NOUN
anesthj-33	35	22	and	and	CCONJ
anesthj-33	35	23	prevention	prevention	NOUN
anesthj-33	35	24	of	of	ADP
anesthj-33	35	25	postoperative	postoperative	ADJ
anesthj-33	35	26	nausea	nausea	NOUN
anesthj-33	35	27	and	and	CCONJ
anesthj-33	35	28	vomiting	vomiting	NOUN
anesthj-33	35	29	.	.	PUNCT
anesthj-33	36	1	general	general	ADJ
anesthj-33	36	2	endotracheal	endotracheal	PROPN
anesthj-33	36	3	anesthesia	anesthesia	PROPN
anesthj-33	36	4	was	be	AUX
anesthj-33	36	5	instituted	institute	VERB
anesthj-33	36	6	by	by	ADP
anesthj-33	36	7	use	use	NOUN
anesthj-33	36	8	of	of	ADP
anesthj-33	36	9	a	a	DET
anesthj-33	36	10	conventional	conventional	ADJ
anesthj-33	36	11	macintosh	macintosh	PROPN
anesthj-33	36	12	laryngoscope	laryngoscope	NOUN
anesthj-33	36	13	blade	blade	NOUN
anesthj-33	36	14	(	(	PUNCT
anesthj-33	36	15	welch	welch	PROPN
anesthj-33	36	16	allyn	allyn	PROPN
anesthj-33	36	17	,	,	PUNCT
anesthj-33	36	18	skaneateles	skaneateles	PROPN
anesthj-33	36	19	falls	fall	VERB
anesthj-33	36	20	,	,	PUNCT
anesthj-33	36	21	ny	ny	PROPN
anesthj-33	36	22	)	)	PUNCT
anesthj-33	36	23	,	,	PUNCT
anesthj-33	36	24	the	the	DET
anesthj-33	36	25	muscle	muscle	NOUN
anesthj-33	36	26	relaxant	relaxant	ADJ
anesthj-33	36	27	cisatracurium	cisatracurium	NOUN
anesthj-33	36	28	20	20	NUM
anesthj-33	36	29	mg	mg	PROPN
anesthj-33	36	30	,	,	PUNCT
anesthj-33	36	31	and	and	CCONJ
anesthj-33	36	32	the	the	DET
anesthj-33	36	33	induction	induction	NOUN
anesthj-33	36	34	agents	agent	NOUN
anesthj-33	36	35	of	of	ADP
anesthj-33	36	36	propofol	propofol	NOUN
anesthj-33	36	37	50	50	NUM
anesthj-33	36	38	mg	mg	NOUN
anesthj-33	36	39	,	,	PUNCT
anesthj-33	36	40	lidocaine	lidocaine	NOUN
anesthj-33	36	41	1	1	NUM
anesthj-33	36	42	%	%	NOUN
anesthj-33	36	43	60	60	NUM
anesthj-33	36	44	mg	mg	PROPN
anesthj-33	36	45	,	,	PUNCT
anesthj-33	36	46	and	and	CCONJ
anesthj-33	36	47	sufentanil	sufentanil	VERB
anesthj-33	36	48	15	15	NUM
anesthj-33	36	49	mcg	mcg	NOUN
anesthj-33	36	50	.	.	PUNCT
anesthj-33	37	1	after	after	ADP
anesthj-33	37	2	securement	securement	NOUN
anesthj-33	37	3	of	of	ADP
anesthj-33	37	4	the	the	DET
anesthj-33	37	5	airway	airway	NOUN
anesthj-33	37	6	,	,	PUNCT
anesthj-33	37	7	another	another	DET
anesthj-33	37	8	large	large	ADJ
anesthj-33	37	9	-	-	PUNCT
anesthj-33	37	10	bore	bore	NOUN
anesthj-33	37	11	intravenous	intravenous	ADJ
anesthj-33	37	12	catheter	catheter	NOUN
anesthj-33	37	13	and	and	CCONJ
anesthj-33	37	14	an	an	DET
anesthj-33	37	15	arterial	arterial	ADJ
anesthj-33	37	16	catheter	catheter	NOUN
anesthj-33	37	17	were	be	AUX
anesthj-33	37	18	started	start	VERB
anesthj-33	37	19	before	before	ADP
anesthj-33	37	20	the	the	DET
anesthj-33	37	21	start	start	NOUN
anesthj-33	37	22	of	of	ADP
anesthj-33	37	23	the	the	DET
anesthj-33	37	24	case	case	NOUN
anesthj-33	37	25	.	.	PUNCT
anesthj-33	38	1	maintenance	maintenance	NOUN
anesthj-33	38	2	anesthesia	anesthesia	PROPN
anesthj-33	38	3	was	be	AUX
anesthj-33	38	4	continued	continue	VERB
anesthj-33	38	5	with	with	ADP
anesthj-33	38	6	a	a	DET
anesthj-33	38	7	propofol	propofol	ADJ
anesthj-33	38	8	infusion	infusion	NOUN
anesthj-33	38	9	set	set	VERB
anesthj-33	38	10	initially	initially	ADV
anesthj-33	38	11	to	to	ADP
anesthj-33	38	12	50	50	NUM
anesthj-33	38	13	mcg/	mcg/	NOUN
anesthj-33	38	14	kg	kg	PROPN
anesthj-33	38	15	/	/	SYM
anesthj-33	38	16	min	min	PROPN
anesthj-33	38	17	,	,	PUNCT
anesthj-33	38	18	sevoflurane	sevoflurane	NOUN
anesthj-33	38	19	at	at	ADP
anesthj-33	38	20	a	a	DET
anesthj-33	38	21	goal	goal	NOUN
anesthj-33	38	22	end	end	VERB
anesthj-33	38	23	tidal	tidal	ADJ
anesthj-33	38	24	concentration	concentration	NOUN
anesthj-33	38	25	of	of	ADP
anesthj-33	38	26	1.5	1.5	NUM
anesthj-33	38	27	,	,	PUNCT
anesthj-33	38	28	<	<	X
anesthj-33	38	29	1	1	NUM
anesthj-33	38	30	minimum	minimum	ADJ
anesthj-33	38	31	alveolar	alveolar	ADJ
anesthj-33	38	32	concentration	concentration	NOUN
anesthj-33	38	33	(	(	PUNCT
anesthj-33	38	34	mac	mac	NOUN
anesthj-33	38	35	)	)	PUNCT
anesthj-33	38	36	,	,	PUNCT
anesthj-33	38	37	and	and	CCONJ
anesthj-33	38	38	boluses	bolus	NOUN
anesthj-33	38	39	of	of	ADP
anesthj-33	38	40	10	10	NUM
anesthj-33	38	41	mcg	mcg	NOUN
anesthj-33	38	42	of	of	ADP
anesthj-33	38	43	sufentanil	sufentanil	NOUN
anesthj-33	38	44	as	as	SCONJ
anesthj-33	38	45	needed	need	VERB
anesthj-33	38	46	.	.	PUNCT
anesthj-33	39	1	the	the	DET
anesthj-33	39	2	patient	patient	NOUN
anesthj-33	39	3	was	be	AUX
anesthj-33	39	4	to	to	PART
anesthj-33	39	5	be	be	AUX
anesthj-33	39	6	woken	wake	VERB
anesthj-33	39	7	up	up	ADP
anesthj-33	39	8	fully	fully	ADV
anesthj-33	39	9	on	on	ADP
anesthj-33	39	10	emergence	emergence	NOUN
anesthj-33	39	11	with	with	ADP
anesthj-33	39	12	evidence	evidence	NOUN
anesthj-33	39	13	of	of	ADP
anesthj-33	39	14	eye	eye	NOUN
anesthj-33	39	15	opening	opening	NOUN
anesthj-33	39	16	,	,	PUNCT
anesthj-33	39	17	spontaneous	spontaneous	ADJ
anesthj-33	39	18	ventilation	ventilation	NOUN
anesthj-33	39	19	,	,	PUNCT
anesthj-33	39	20	and	and	CCONJ
anesthj-33	39	21	sustained	sustain	VERB
anesthj-33	39	22	head	head	NOUN
anesthj-33	39	23	lift	lift	NOUN
anesthj-33	39	24	to	to	PART
anesthj-33	39	25	ensure	ensure	VERB
anesthj-33	39	26	adequate	adequate	ADJ
anesthj-33	39	27	return	return	NOUN
anesthj-33	39	28	of	of	ADP
anesthj-33	39	29	respiratory	respiratory	ADJ
anesthj-33	39	30	drive	drive	NOUN
anesthj-33	39	31	prior	prior	ADV
anesthj-33	39	32	to	to	ADP
anesthj-33	39	33	extubation	extubation	NOUN
anesthj-33	39	34	.	.	PUNCT
anesthj-33	40	1	upon	upon	SCONJ
anesthj-33	40	2	arrival	arrival	NOUN
anesthj-33	40	3	in	in	ADP
anesthj-33	40	4	the	the	DET
anesthj-33	40	5	operating	operating	NOUN
anesthj-33	40	6	room	room	NOUN
anesthj-33	40	7	,	,	PUNCT
anesthj-33	40	8	the	the	DET
anesthj-33	40	9	patient	patient	NOUN
anesthj-33	40	10	was	be	AUX
anesthj-33	40	11	preoxygenated	preoxygenate	VERB
anesthj-33	40	12	with	with	ADP
anesthj-33	40	13	100	100	NUM
anesthj-33	40	14	%	%	NOUN
anesthj-33	40	15	oxygen	oxygen	NOUN
anesthj-33	40	16	for	for	ADP
anesthj-33	40	17	2	2	NUM
anesthj-33	40	18	minutes	minute	NOUN
anesthj-33	40	19	with	with	ADP
anesthj-33	40	20	10	10	NUM
anesthj-33	40	21	l	l	NOUN
anesthj-33	40	22	oxygen	oxygen	NOUN
anesthj-33	40	23	through	through	ADP
anesthj-33	40	24	a	a	DET
anesthj-33	40	25	mask	mask	NOUN
anesthj-33	40	26	.	.	PUNCT
anesthj-33	41	1	pre	pre	ADJ
anesthj-33	41	2	-	-	ADJ
anesthj-33	41	3	induction	induction	ADJ
anesthj-33	41	4	vital	vital	ADJ
anesthj-33	41	5	signs	sign	NOUN
anesthj-33	41	6	were	be	AUX
anesthj-33	41	7	heart	heart	NOUN
anesthj-33	41	8	rate	rate	NOUN
anesthj-33	41	9	of	of	ADP
anesthj-33	41	10	92	92	NUM
anesthj-33	41	11	beats	beat	NOUN
anesthj-33	41	12	per	per	ADP
anesthj-33	41	13	minute	minute	NOUN
anesthj-33	41	14	,	,	PUNCT
anesthj-33	41	15	normal	normal	ADJ
anesthj-33	41	16	sinus	sinu	NOUN
anesthj-33	41	17	rhythm	rhythm	NOUN
anesthj-33	41	18	,	,	PUNCT
anesthj-33	41	19	skin	skin	NOUN
anesthj-33	41	20	temperature	temperature	NOUN
anesthj-33	41	21	of	of	ADP
anesthj-33	41	22	36	36	NUM
anesthj-33	41	23	degrees	degree	NOUN
anesthj-33	41	24	celsius	celsius	NOUN
anesthj-33	41	25	,	,	PUNCT
anesthj-33	41	26	noninvasive	noninvasive	ADJ
anesthj-33	41	27	blood	blood	NOUN
anesthj-33	41	28	pressure	pressure	NOUN
anesthj-33	41	29	of	of	ADP
anesthj-33	41	30	111/82	111/82	NUM
anesthj-33	41	31	mm	mm	NUM
anesthj-33	41	32	hg	hg	NOUN
anesthj-33	41	33	,	,	PUNCT
anesthj-33	41	34	and	and	CCONJ
anesthj-33	41	35	spo2	spo2	PROPN
anesthj-33	41	36	of	of	ADP
anesthj-33	41	37	100	100	NUM
anesthj-33	41	38	%	%	NOUN
anesthj-33	41	39	as	as	SCONJ
anesthj-33	41	40	measured	measure	VERB
anesthj-33	41	41	by	by	ADP
anesthj-33	41	42	pulse	pulse	NOUN
anesthj-33	41	43	oximetry	oximetry	NOUN
anesthj-33	41	44	.	.	PUNCT
anesthj-33	42	1	intravenous	intravenous	ADJ
anesthj-33	42	2	induction	induction	NOUN
anesthj-33	42	3	medications	medication	NOUN
anesthj-33	42	4	included	include	VERB
anesthj-33	42	5	those	those	PRON
anesthj-33	42	6	mentioned	mention	VERB
anesthj-33	42	7	previously	previously	ADV
anesthj-33	42	8	in	in	ADP
anesthj-33	42	9	the	the	DET
anesthj-33	42	10	anesthetic	anesthetic	ADJ
anesthj-33	42	11	plan	plan	NOUN
anesthj-33	42	12	.	.	PUNCT
anesthj-33	43	1	induction	induction	NOUN
anesthj-33	43	2	was	be	AUX
anesthj-33	43	3	initiated	initiate	VERB
anesthj-33	43	4	with	with	ADP
anesthj-33	43	5	a	a	DET
anesthj-33	43	6	conventional	conventional	ADJ
anesthj-33	43	7	macintosh	macintosh	NOUN
anesthj-33	43	8	3	3	NUM
anesthj-33	43	9	laryngoscope	laryngoscope	NOUN
anesthj-33	43	10	blade	blade	NOUN
anesthj-33	43	11	.	.	PUNCT
anesthj-33	44	1	upon	upon	SCONJ
anesthj-33	44	2	visualization	visualization	NOUN
anesthj-33	44	3	of	of	ADP
anesthj-33	44	4	the	the	DET
anesthj-33	44	5	airway	airway	NOUN
anesthj-33	44	6	,	,	PUNCT
anesthj-33	44	7	a	a	DET
anesthj-33	44	8	cormack	cormack	PROPN
anesthj-33	44	9	-	-	PUNCT
anesthj-33	44	10	lehane	lehane	PROPN
anesthj-33	44	11	grade	grade	NOUN
anesthj-33	44	12	4	4	NUM
anesthj-33	44	13	was	be	AUX
anesthj-33	44	14	assessed	assess	VERB
anesthj-33	44	15	.	.	PUNCT
anesthj-33	45	1	a	a	DET
anesthj-33	45	2	gum	gum	NOUN
anesthj-33	45	3	elastic	elastic	ADJ
anesthj-33	45	4	bougie	bougie	NOUN
anesthj-33	45	5	tube	tube	NOUN
anesthj-33	45	6	introducer	introducer	NOUN
anesthj-33	45	7	was	be	AUX
anesthj-33	45	8	passed	pass	VERB
anesthj-33	45	9	with	with	ADP
anesthj-33	45	10	successful	successful	ADJ
anesthj-33	45	11	placement	placement	NOUN
anesthj-33	45	12	of	of	ADP
anesthj-33	45	13	a	a	DET
anesthj-33	45	14	size	size	NOUN
anesthj-33	45	15	7.5	7.5	NUM
anesthj-33	45	16	-	-	PUNCT
anesthj-33	45	17	mm	mm	NOUN
anesthj-33	45	18	endotracheal	endotracheal	NOUN
anesthj-33	45	19	tube	tube	NOUN
anesthj-33	45	20	.	.	PUNCT
anesthj-33	46	1	confirmation	confirmation	NOUN
anesthj-33	46	2	of	of	ADP
anesthj-33	46	3	adequate	adequate	ADJ
anesthj-33	46	4	placement	placement	NOUN
anesthj-33	46	5	was	be	AUX
anesthj-33	46	6	by	by	ADP
anesthj-33	46	7	auscultation	auscultation	NOUN
anesthj-33	46	8	of	of	ADP
anesthj-33	46	9	equal	equal	ADJ
anesthj-33	46	10	bilateral	bilateral	ADJ
anesthj-33	46	11	breath	breath	NOUN
anesthj-33	46	12	sounds	sound	NOUN
anesthj-33	46	13	,	,	PUNCT
anesthj-33	46	14	bilateral	bilateral	ADJ
anesthj-33	46	15	chest	chest	NOUN
anesthj-33	46	16	rise	rise	NOUN
anesthj-33	46	17	,	,	PUNCT
anesthj-33	46	18	and	and	CCONJ
anesthj-33	46	19	positive	positive	ADJ
anesthj-33	46	20	end	end	NOUN
anesthj-33	46	21	tidal	tidal	ADJ
anesthj-33	46	22	carbon	carbon	NOUN
anesthj-33	46	23	dioxide	dioxide	NOUN
anesthj-33	46	24	at	at	ADP
anesthj-33	46	25	39	39	NUM
anesthj-33	46	26	mm	mm	NUM
anesthj-33	46	27	hg	hg	PROPN
anesthj-33	46	28	.	.	PROPN
anesthj-33	47	1	sevoflurane	sevoflurane	PROPN
anesthj-33	47	2	gas	gas	NOUN
anesthj-33	47	3	was	be	AUX
anesthj-33	47	4	turned	turn	VERB
anesthj-33	47	5	on	on	ADP
anesthj-33	47	6	to	to	ADP
anesthj-33	47	7	1.5	1.5	NUM
anesthj-33	47	8	%	%	NOUN
anesthj-33	47	9	with	with	ADP
anesthj-33	47	10	an	an	DET
anesthj-33	47	11	end	end	NOUN
anesthj-33	47	12	tidal	tidal	ADJ
anesthj-33	47	13	concentration	concentration	NOUN
anesthj-33	47	14	of	of	ADP
anesthj-33	47	15	1.0	1.0	NUM
anesthj-33	47	16	with	with	ADP
anesthj-33	47	17	2	2	NUM
anesthj-33	47	18	l	l	NOUN
anesthj-33	47	19	of	of	ADP
anesthj-33	47	20	oxygen	oxygen	NOUN
anesthj-33	47	21	.	.	PUNCT
anesthj-33	48	1	the	the	DET
anesthj-33	48	2	patient	patient	NOUN
anesthj-33	48	3	was	be	AUX
anesthj-33	48	4	placed	place	VERB
anesthj-33	48	5	on	on	ADP
anesthj-33	48	6	volume	volume	NOUN
anesthj-33	48	7	control	control	NOUN
anesthj-33	48	8	mode	mode	NOUN
anesthj-33	48	9	on	on	ADP
anesthj-33	48	10	the	the	DET
anesthj-33	48	11	mechanical	mechanical	ADJ
anesthj-33	48	12	ventilator	ventilator	NOUN
anesthj-33	48	13	with	with	ADP
anesthj-33	48	14	a	a	DET
anesthj-33	48	15	tidal	tidal	ADJ
anesthj-33	48	16	volume	volume	NOUN
anesthj-33	48	17	of	of	ADP
anesthj-33	48	18	400	400	NUM
anesthj-33	48	19	ml	ml	NOUN
anesthj-33	48	20	,	,	PUNCT
anesthj-33	48	21	rate	rate	NOUN
anesthj-33	48	22	of	of	ADP
anesthj-33	48	23	10	10	NUM
anesthj-33	48	24	breaths	breath	NOUN
anesthj-33	48	25	per	per	ADP
anesthj-33	48	26	minute	minute	NOUN
anesthj-33	48	27	,	,	PUNCT
anesthj-33	48	28	and	and	CCONJ
anesthj-33	48	29	positive	positive	ADJ
anesthj-33	48	30	inspiratory	inspiratory	NOUN
anesthj-33	48	31	pressure	pressure	NOUN
anesthj-33	48	32	of	of	ADP
anesthj-33	48	33	14	14	NUM
anesthj-33	48	34	mm	mm	NUM
anesthj-33	48	35	hg	hg	NOUN
anesthj-33	48	36	.	.	PUNCT
anesthj-33	49	1	immediately	immediately	ADV
anesthj-33	49	2	after	after	ADV
anesthj-33	49	3	,	,	PUNCT
anesthj-33	49	4	another	another	DET
anesthj-33	49	5	18	18	NUM
anesthj-33	49	6	-	-	PUNCT
anesthj-33	49	7	gauge	gauge	NOUN
anesthj-33	49	8	peripheral	peripheral	ADJ
anesthj-33	49	9	intravenous	intravenous	ADJ
anesthj-33	49	10	catheter	catheter	NOUN
anesthj-33	49	11	in	in	ADP
anesthj-33	49	12	the	the	DET
anesthj-33	49	13	left	left	ADJ
anesthj-33	49	14	arm	arm	NOUN
anesthj-33	49	15	and	and	CCONJ
anesthj-33	49	16	a	a	DET
anesthj-33	49	17	20	20	NUM
anesthj-33	49	18	-	-	PUNCT
anesthj-33	49	19	gauge	gauge	NOUN
anesthj-33	49	20	right	right	ADJ
anesthj-33	49	21	radial	radial	ADJ
anesthj-33	49	22	catheter	catheter	NOUN
anesthj-33	49	23	were	be	AUX
anesthj-33	49	24	started	start	VERB
anesthj-33	49	25	,	,	PUNCT
anesthj-33	49	26	1	1	NUM
anesthj-33	49	27	g	g	NOUN
anesthj-33	49	28	of	of	ADP
anesthj-33	49	29	cefazolin	cefazolin	PROPN
anesthj-33	49	30	was	be	AUX
anesthj-33	49	31	administered	administer	VERB
anesthj-33	49	32	intravenously	intravenously	ADV
anesthj-33	49	33	,	,	PUNCT
anesthj-33	49	34	and	and	CCONJ
anesthj-33	49	35	a	a	DET
anesthj-33	49	36	propofol	propofol	ADJ
anesthj-33	49	37	infusion	infusion	NOUN
anesthj-33	49	38	was	be	AUX
anesthj-33	49	39	started	start	VERB
anesthj-33	49	40	.	.	PUNCT
anesthj-33	50	1	a	a	DET
anesthj-33	50	2	forced	force	VERB
anesthj-33	50	3	air	air	NOUN
anesthj-33	50	4	warmer	warm	ADJ
anesthj-33	50	5	and	and	CCONJ
anesthj-33	50	6	an	an	DET
anesthj-33	50	7	intravenous	intravenous	ADJ
anesthj-33	50	8	fluid	fluid	NOUN
anesthj-33	50	9	warmer	warm	ADJ
anesthj-33	50	10	were	be	AUX
anesthj-33	50	11	used	use	VERB
anesthj-33	50	12	to	to	PART
anesthj-33	50	13	maintain	maintain	VERB
anesthj-33	50	14	patient	patient	ADJ
anesthj-33	50	15	normothermia	normothermia	NOUN
anesthj-33	50	16	.	.	PUNCT
anesthj-33	51	1	the	the	DET
anesthj-33	51	2	intraoperative	intraoperative	ADJ
anesthj-33	51	3	course	course	NOUN
anesthj-33	51	4	remained	remain	VERB
anesthj-33	51	5	uneventful	uneventful	ADJ
anesthj-33	51	6	.	.	PUNCT
anesthj-33	52	1	sufentanil	sufentanil	NOUN
anesthj-33	52	2	boluses	bolus	NOUN
anesthj-33	52	3	of	of	ADP
anesthj-33	52	4	10	10	NUM
anesthj-33	52	5	and	and	CCONJ
anesthj-33	52	6	15	15	NUM
anesthj-33	52	7	mcg	mcg	NOUN
anesthj-33	52	8	were	be	AUX
anesthj-33	52	9	given	give	VERB
anesthj-33	52	10	for	for	ADP
anesthj-33	52	11	pain	pain	NOUN
anesthj-33	52	12	control	control	NOUN
anesthj-33	52	13	as	as	ADV
anesthj-33	52	14	well	well	ADV
anesthj-33	52	15	as	as	ADP
anesthj-33	52	16	100	100	NUM
anesthj-33	52	17	-	-	PUNCT
anesthj-33	52	18	mcg	mcg	NOUN
anesthj-33	52	19	boluses	bolus	NOUN
anesthj-33	52	20	of	of	ADP
anesthj-33	52	21	neo	neo	ADJ
anesthj-33	52	22	-	-	NOUN
anesthj-33	52	23	synephrine	synephrine	ADJ
anesthj-33	52	24	(	(	PUNCT
anesthj-33	52	25	phenylephrine	phenylephrine	NOUN
anesthj-33	52	26	)	)	PUNCT
anesthj-33	52	27	to	to	PART
anesthj-33	52	28	help	help	VERB
anesthj-33	52	29	maintain	maintain	VERB
anesthj-33	52	30	systolic	systolic	ADJ
anesthj-33	52	31	blood	blood	NOUN
anesthj-33	52	32	pressure	pressure	NOUN
anesthj-33	52	33	>	>	X
anesthj-33	52	34	90	90	NUM
anesthj-33	52	35	mm	mm	NUM
anesthj-33	52	36	hg	hg	NOUN
anesthj-33	52	37	.	.	PUNCT
anesthj-33	53	1	no	no	DET
anesthj-33	53	2	additional	additional	ADJ
anesthj-33	53	3	muscle	muscle	NOUN
anesthj-33	53	4	relaxant	relaxant	NOUN
anesthj-33	53	5	was	be	AUX
anesthj-33	53	6	given	give	VERB
anesthj-33	53	7	.	.	PUNCT
anesthj-33	54	1	acetaminophen	acetaminophen	NOUN
anesthj-33	54	2	1	1	NUM
anesthj-33	54	3	g	g	NOUN
anesthj-33	54	4	was	be	AUX
anesthj-33	54	5	also	also	ADV
anesthj-33	54	6	administered	administer	VERB
anesthj-33	54	7	intravenously	intravenously	ADV
anesthj-33	54	8	before	before	ADP
anesthj-33	54	9	the	the	DET
anesthj-33	54	10	end	end	NOUN
anesthj-33	54	11	of	of	ADP
anesthj-33	54	12	the	the	DET
anesthj-33	54	13	case	case	NOUN
anesthj-33	54	14	.	.	PUNCT
anesthj-33	55	1	the	the	DET
anesthj-33	55	2	total	total	NOUN
anesthj-33	55	3	crystalloid	crystalloid	NOUN
anesthj-33	55	4	for	for	ADP
anesthj-33	55	5	the	the	DET
anesthj-33	55	6	procedure	procedure	NOUN
anesthj-33	55	7	was	be	AUX
anesthj-33	55	8	1200	1200	NUM
anesthj-33	55	9	ml	ml	NOUN
anesthj-33	55	10	of	of	ADP
anesthj-33	55	11	lactated	lactated	ADJ
anesthj-33	55	12	ringer	ringer	NOUN
anesthj-33	55	13	’s	’s	PART
anesthj-33	55	14	solution	solution	NOUN
anesthj-33	55	15	.	.	PUNCT
anesthj-33	56	1	foley	foley	PROPN
anesthj-33	56	2	catheter	catheter	PROPN
anesthj-33	56	3	output	output	NOUN
anesthj-33	56	4	was	be	AUX
anesthj-33	56	5	300	300	NUM
anesthj-33	56	6	ml	ml	NOUN
anesthj-33	56	7	of	of	ADP
anesthj-33	56	8	dark	dark	ADJ
anesthj-33	56	9	amber	amber	PROPN
anesthj-33	56	10	urine	urine	NOUN
anesthj-33	56	11	.	.	PUNCT
anesthj-33	57	1	estimated	estimate	VERB
anesthj-33	57	2	blood	blood	NOUN
anesthj-33	57	3	loss	loss	NOUN
anesthj-33	57	4	was	be	AUX
anesthj-33	57	5	minimal	minimal	ADJ
anesthj-33	57	6	at	at	ADP
anesthj-33	57	7	50	50	NUM
anesthj-33	57	8	ml	ml	NOUN
anesthj-33	57	9	.	.	PUNCT
anesthj-33	58	1	upon	upon	SCONJ
anesthj-33	58	2	emergence	emergence	NOUN
anesthj-33	58	3	,	,	PUNCT
anesthj-33	58	4	the	the	DET
anesthj-33	58	5	patient	patient	NOUN
anesthj-33	58	6	was	be	AUX
anesthj-33	58	7	extubated	extubate	VERB
anesthj-33	58	8	awake	awake	ADJ
anesthj-33	58	9	,	,	PUNCT
anesthj-33	58	10	was	be	AUX
anesthj-33	58	11	spontaneously	spontaneously	ADV
anesthj-33	58	12	ventilating	ventilate	VERB
anesthj-33	58	13	for	for	ADP
anesthj-33	58	14	30	30	NUM
anesthj-33	58	15	minutes	minute	NOUN
anesthj-33	58	16	with	with	ADP
anesthj-33	58	17	no	no	DET
anesthj-33	58	18	pressure	pressure	NOUN
anesthj-33	58	19	support	support	NOUN
anesthj-33	58	20	,	,	PUNCT
anesthj-33	58	21	with	with	ADP
anesthj-33	58	22	eye	eye	NOUN
anesthj-33	58	23	opening	opening	NOUN
anesthj-33	58	24	,	,	PUNCT
anesthj-33	58	25	and	and	CCONJ
anesthj-33	58	26	with	with	ADP
anesthj-33	58	27	sustained	sustained	ADJ
anesthj-33	58	28	head	head	NOUN
anesthj-33	58	29	lift	lift	NOUN
anesthj-33	58	30	to	to	ADP
anesthj-33	58	31	10	10	NUM
anesthj-33	58	32	l	l	NOUN
anesthj-33	58	33	of	of	ADP
anesthj-33	58	34	oxygen	oxygen	NOUN
anesthj-33	58	35	via	via	ADP
anesthj-33	58	36	a	a	DET
anesthj-33	58	37	non	non	ADJ
anesthj-33	58	38	-	-	ADJ
anesthj-33	58	39	rebreather	rebreather	ADJ
anesthj-33	58	40	face	face	NOUN
anesthj-33	58	41	mask	mask	NOUN
anesthj-33	58	42	at	at	ADP
anesthj-33	58	43	an	an	DET
anesthj-33	58	44	end	end	NOUN
anesthj-33	58	45	tidal	tidal	ADJ
anesthj-33	58	46	sevoflurane	sevoflurane	ADJ
anesthj-33	58	47	concentration	concentration	NOUN
anesthj-33	58	48	of	of	ADP
anesthj-33	58	49	0.3	0.3	NUM
anesthj-33	58	50	.	.	PUNCT
anesthj-33	59	1	discussion	discussion	NOUN
anesthj-33	59	2	mms	mms	NOUN
anesthj-33	59	3	were	be	AUX
anesthj-33	59	4	first	first	ADV
anesthj-33	59	5	discovered	discover	VERB
anesthj-33	59	6	56	56	NUM
anesthj-33	59	7	years	year	NOUN
anesthj-33	59	8	ago	ago	ADV
anesthj-33	59	9	in	in	ADP
anesthj-33	59	10	a	a	DET
anesthj-33	59	11	patient	patient	NOUN
anesthj-33	59	12	who	who	PRON
anesthj-33	59	13	had	have	VERB
anesthj-33	59	14	large	large	ADJ
anesthj-33	59	15	amounts	amount	NOUN
anesthj-33	59	16	of	of	ADP
anesthj-33	59	17	mitochondria	mitochondria	NOUN
anesthj-33	59	18	in	in	ADP
anesthj-33	59	19	skeletal	skeletal	ADJ
anesthj-33	59	20	muscle.3	muscle.3	PROPN
anesthj-33	59	21	these	these	DET
anesthj-33	59	22	diseases	disease	NOUN
anesthj-33	59	23	cause	cause	VERB
anesthj-33	59	24	a	a	DET
anesthj-33	59	25	wide	wide	ADJ
anesthj-33	59	26	range	range	NOUN
anesthj-33	59	27	of	of	ADP
anesthj-33	59	28	clinical	clinical	ADJ
anesthj-33	59	29	problems	problem	NOUN
anesthj-33	59	30	,	,	PUNCT
anesthj-33	59	31	including	include	VERB
anesthj-33	59	32	leber	leber	PROPN
anesthj-33	59	33	’s	’s	PART
anesthj-33	59	34	hereditary	hereditary	ADJ
anesthj-33	59	35	optic	optic	NOUN
anesthj-33	59	36	neuropathy	neuropathy	ADJ
anesthj-33	59	37	,	,	PUNCT
anesthj-33	59	38	chronic	chronic	ADJ
anesthj-33	59	39	progressive	progressive	ADJ
anesthj-33	59	40	ophthalmoplegia	ophthalmoplegia	NOUN
anesthj-33	59	41	,	,	PUNCT
anesthj-33	59	42	kearns	kearn	NOUN
anesthj-33	59	43	-	-	PUNCT
anesthj-33	59	44	sayre	sayre	PROPN
anesthj-33	59	45	syndrome	syndrome	PROPN
anesthj-33	59	46	,	,	PUNCT
anesthj-33	59	47	myoclonic	myoclonic	ADJ
anesthj-33	59	48	epilepsy	epilepsy	NOUN
anesthj-33	59	49	and	and	CCONJ
anesthj-33	59	50	ragged	ragged	ADJ
anesthj-33	59	51	-	-	PUNCT
anesthj-33	59	52	red	red	ADJ
anesthj-33	59	53	fiber	fiber	NOUN
anesthj-33	59	54	disease	disease	NOUN
anesthj-33	59	55	,	,	PUNCT
anesthj-33	59	56	and	and	CCONJ
anesthj-33	59	57	melas.3	melas.3	VERB
anesthj-33	59	58	the	the	DET
anesthj-33	59	59	anesthetic	anesthetic	ADJ
anesthj-33	59	60	management	management	NOUN
anesthj-33	59	61	of	of	ADP
anesthj-33	59	62	patients	patient	NOUN
anesthj-33	59	63	with	with	ADP
anesthj-33	59	64	mms	mms	NOUN
anesthj-33	59	65	such	such	ADJ
anesthj-33	59	66	as	as	ADP
anesthj-33	59	67	melas	mela	NOUN
anesthj-33	59	68	is	be	AUX
anesthj-33	59	69	complicated	complicated	ADJ
anesthj-33	59	70	for	for	ADP
anesthj-33	59	71	many	many	ADJ
anesthj-33	59	72	reasons	reason	NOUN
anesthj-33	59	73	involving	involve	VERB
anesthj-33	59	74	genetic	genetic	ADJ
anesthj-33	59	75	inheritance	inheritance	NOUN
anesthj-33	59	76	and	and	CCONJ
anesthj-33	59	77	mutation	mutation	NOUN
anesthj-33	59	78	as	as	ADV
anesthj-33	59	79	well	well	ADV
anesthj-33	59	80	as	as	ADP
anesthj-33	59	81	the	the	DET
anesthj-33	59	82	varying	vary	VERB
anesthj-33	59	83	phenotypic	phenotypic	ADJ
anesthj-33	59	84	presentations	presentation	NOUN
anesthj-33	59	85	of	of	ADP
anesthj-33	59	86	these	these	DET
anesthj-33	59	87	diseases	disease	NOUN
anesthj-33	59	88	.	.	PUNCT
anesthj-33	60	1	the	the	DET
anesthj-33	60	2	same	same	ADJ
anesthj-33	60	3	genetic	genetic	ADJ
anesthj-33	60	4	mutation	mutation	NOUN
anesthj-33	60	5	in	in	ADP
anesthj-33	60	6	mitochondrial	mitochondrial	ADJ
anesthj-33	60	7	dna	dna	NOUN
anesthj-33	60	8	may	may	AUX
anesthj-33	60	9	have	have	VERB
anesthj-33	60	10	different	different	ADJ
anesthj-33	60	11	phenotypes	phenotype	NOUN
anesthj-33	60	12	in	in	ADP
anesthj-33	60	13	different	different	ADJ
anesthj-33	60	14	patients	patient	NOUN
anesthj-33	60	15	,	,	PUNCT
anesthj-33	60	16	while	while	SCONJ
anesthj-33	60	17	different	different	ADJ
anesthj-33	60	18	genetic	genetic	ADJ
anesthj-33	60	19	mutations	mutation	NOUN
anesthj-33	60	20	can	can	AUX
anesthj-33	60	21	also	also	ADV
anesthj-33	60	22	cause	cause	VERB
anesthj-33	60	23	overlapping	overlap	VERB
anesthj-33	60	24	phenotypes.3	phenotypes.3	NOUN
anesthj-33	60	25	thus	thus	ADV
anesthj-33	60	26	,	,	PUNCT
anesthj-33	60	27	the	the	DET
anesthj-33	60	28	safe	safe	ADJ
anesthj-33	60	29	use	use	NOUN
anesthj-33	60	30	of	of	ADP
anesthj-33	60	31	an	an	DET
anesthj-33	60	32	anesthetic	anesthetic	ADJ
anesthj-33	60	33	technique	technique	NOUN
anesthj-33	60	34	in	in	ADP
anesthj-33	60	35	a	a	DET
anesthj-33	60	36	patient	patient	NOUN
anesthj-33	60	37	with	with	ADP
anesthj-33	60	38	one	one	NUM
anesthj-33	60	39	mitochondrial	mitochondrial	ADJ
anesthj-33	60	40	defect	defect	NOUN
anesthj-33	60	41	may	may	AUX
anesthj-33	60	42	not	not	PART
anesthj-33	60	43	translate	translate	VERB
anesthj-33	60	44	to	to	PART
anesthj-33	60	45	equal	equal	ADJ
anesthj-33	60	46	safety	safety	NOUN
anesthj-33	60	47	across	across	ADP
anesthj-33	60	48	other	other	ADJ
anesthj-33	60	49	mitochondrial	mitochondrial	ADJ
anesthj-33	60	50	diseases	disease	NOUN
anesthj-33	60	51	with	with	ADP
anesthj-33	60	52	identical	identical	ADJ
anesthj-33	60	53	mutations.5	mutations.5	NOUN
anesthj-33	60	54	one	one	NUM
anesthj-33	60	55	of	of	ADP
anesthj-33	60	56	the	the	DET
anesthj-33	60	57	genetic	genetic	ADJ
anesthj-33	60	58	mutations	mutation	NOUN
anesthj-33	60	59	that	that	PRON
anesthj-33	60	60	has	have	AUX
anesthj-33	60	61	been	be	AUX
anesthj-33	60	62	attributed	attribute	VERB
anesthj-33	60	63	to	to	ADP
anesthj-33	60	64	melas	melas	PROPN
anesthj-33	60	65	has	have	AUX
anesthj-33	60	66	been	be	AUX
anesthj-33	60	67	identified	identify	VERB
anesthj-33	60	68	as	as	ADP
anesthj-33	60	69	mttl1*melas3243	mttl1*melas3243	NOUN
anesthj-33	60	70	g	g	NOUN
anesthj-33	60	71	in	in	ADP
anesthj-33	60	72	the	the	DET
anesthj-33	60	73	trnaleu	trnaleu	NOUN
anesthj-33	60	74	that	that	PRON
anesthj-33	60	75	affects	affect	VERB
anesthj-33	60	76	complex	complex	ADJ
anesthj-33	60	77	i	i	PRON
anesthj-33	60	78	of	of	ADP
anesthj-33	60	79	the	the	DET
anesthj-33	60	80	respiratory	respiratory	ADJ
anesthj-33	60	81	enzyme	enzyme	NOUN
anesthj-33	60	82	complexes	complex	NOUN
anesthj-33	60	83	involved	involve	VERB
anesthj-33	60	84	in	in	ADP
anesthj-33	60	85	oxidative	oxidative	ADJ
anesthj-33	60	86	phosphorylation.3	phosphorylation.3	ADV
anesthj-33	60	87	this	this	DET
anesthj-33	60	88	mutation	mutation	NOUN
anesthj-33	60	89	in	in	ADP
anesthj-33	60	90	mitochondrial	mitochondrial	ADJ
anesthj-33	60	91	dna	dna	NOUN
anesthj-33	60	92	when	when	SCONJ
anesthj-33	60	93	present	present	ADJ
anesthj-33	60	94	in	in	ADP
anesthj-33	60	95	a	a	DET
anesthj-33	60	96	high	high	ADJ
anesthj-33	60	97	percentage	percentage	NOUN
anesthj-33	60	98	is	be	AUX
anesthj-33	60	99	associated	associate	VERB
anesthj-33	60	100	with	with	ADP
anesthj-33	60	101	stroke	stroke	NOUN
anesthj-33	60	102	-	-	PUNCT
anesthj-33	60	103	like	like	ADJ
anesthj-33	60	104	activity	activity	NOUN
anesthj-33	60	105	but	but	CCONJ
anesthj-33	60	106	when	when	SCONJ
anesthj-33	60	107	present	present	ADJ
anesthj-33	60	108	in	in	ADP
anesthj-33	60	109	a	a	DET
anesthj-33	60	110	low	low	ADJ
anesthj-33	60	111	percentage	percentage	NOUN
anesthj-33	60	112	is	be	AUX
anesthj-33	60	113	associated	associate	VERB
anesthj-33	60	114	with	with	ADP
anesthj-33	60	115	diabetes	diabetes	NOUN
anesthj-33	60	116	and	and	CCONJ
anesthj-33	60	117	deafness.3	deafness.3	VERB
anesthj-33	60	118	the	the	DET
anesthj-33	60	119	patient	patient	NOUN
anesthj-33	60	120	in	in	ADP
anesthj-33	60	121	the	the	DET
anesthj-33	60	122	present	present	ADJ
anesthj-33	60	123	case	case	NOUN
anesthj-33	60	124	report	report	NOUN
anesthj-33	60	125	interestingly	interestingly	ADV
anesthj-33	60	126	had	have	VERB
anesthj-33	60	127	strokelike	strokelike	ADJ
anesthj-33	60	128	activity	activity	NOUN
anesthj-33	60	129	,	,	PUNCT
anesthj-33	60	130	deafness	deafness	NOUN
anesthj-33	60	131	,	,	PUNCT
anesthj-33	60	132	and	and	CCONJ
anesthj-33	60	133	diabetes	diabetes	NOUN
anesthj-33	60	134	.	.	PUNCT
anesthj-33	61	1	another	another	DET
anesthj-33	61	2	source	source	NOUN
anesthj-33	61	3	identifies	identify	VERB
anesthj-33	61	4	the	the	DET
anesthj-33	61	5	affected	affected	ADJ
anesthj-33	61	6	respiratory	respiratory	ADJ
anesthj-33	61	7	complex	complex	NOUN
anesthj-33	61	8	as	as	ADP
anesthj-33	61	9	complex	complex	ADJ
anesthj-33	61	10	iv	iv	NUM
anesthj-33	61	11	;	;	PUNCT
anesthj-33	61	12	other	other	ADJ
anesthj-33	61	13	sources	source	NOUN
anesthj-33	61	14	identify	identify	VERB
anesthj-33	61	15	multiple	multiple	ADJ
anesthj-33	61	16	mitochondrial	mitochondrial	ADJ
anesthj-33	61	17	dna	dna	NOUN
anesthj-33	61	18	gene	gene	NOUN
anesthj-33	61	19	(	(	PUNCT
anesthj-33	61	20	trna	trna	NOUN
anesthj-33	61	21	and	and	CCONJ
anesthj-33	61	22	mrna	mrna	PROPN
anesthj-33	61	23	)	)	PUNCT
anesthj-33	61	24	mutations	mutation	NOUN
anesthj-33	61	25	and	and	CCONJ
anesthj-33	61	26	deletions	deletion	NOUN
anesthj-33	61	27	responsible	responsible	ADJ
anesthj-33	61	28	for	for	ADP
anesthj-33	61	29	melas.1,4,6	melas.1,4,6	PRON
anesthj-33	61	30	the	the	DET
anesthj-33	61	31	patient	patient	NOUN
anesthj-33	61	32	in	in	ADP
anesthj-33	61	33	the	the	DET
anesthj-33	61	34	present	present	ADJ
anesthj-33	61	35	case	case	NOUN
anesthj-33	61	36	did	do	AUX
anesthj-33	61	37	not	not	PART
anesthj-33	61	38	have	have	VERB
anesthj-33	61	39	a	a	DET
anesthj-33	61	40	genetic	genetic	ADJ
anesthj-33	61	41	report	report	NOUN
anesthj-33	61	42	and	and	CCONJ
anesthj-33	61	43	the	the	DET
anesthj-33	61	44	inability	inability	NOUN
anesthj-33	61	45	to	to	PART
anesthj-33	61	46	obtain	obtain	VERB
anesthj-33	61	47	muscle	muscle	NOUN
anesthj-33	61	48	biopsy	biopsy	NOUN
anesthj-33	61	49	records	record	NOUN
anesthj-33	61	50	from	from	ADP
anesthj-33	61	51	his	his	PRON
anesthj-33	61	52	previous	previous	ADJ
anesthj-33	61	53	hospital	hospital	NOUN
anesthj-33	61	54	admission	admission	NOUN
anesthj-33	61	55	made	make	VERB
anesthj-33	61	56	it	it	PRON
anesthj-33	61	57	difficult	difficult	ADJ
anesthj-33	61	58	to	to	PART
anesthj-33	61	59	determine	determine	VERB
anesthj-33	61	60	the	the	DET
anesthj-33	61	61	exact	exact	ADJ
anesthj-33	61	62	inheritance	inheritance	NOUN
anesthj-33	61	63	method	method	NOUN
anesthj-33	61	64	and	and	CCONJ
anesthj-33	61	65	specific	specific	ADJ
anesthj-33	61	66	clinical	clinical	ADJ
anesthj-33	61	67	presentation	presentation	NOUN
anesthj-33	61	68	.	.	PUNCT
anesthj-33	62	1	sources	source	NOUN
anesthj-33	62	2	do	do	AUX
anesthj-33	62	3	,	,	PUNCT
anesthj-33	62	4	however	however	ADV
anesthj-33	62	5	,	,	PUNCT
anesthj-33	62	6	identify	identify	VERB
anesthj-33	62	7	melas	mela	NOUN
anesthj-33	62	8	inheritance	inheritance	NOUN
anesthj-33	62	9	as	as	ADP
anesthj-33	62	10	being	be	AUX
anesthj-33	62	11	maternal	maternal	ADJ
anesthj-33	62	12	in	in	ADP
anesthj-33	62	13	nature.2	nature.2	ADP
anesthj-33	62	14	diagnosis	diagnosis	NOUN
anesthj-33	62	15	of	of	ADP
anesthj-33	62	16	melas	mela	NOUN
anesthj-33	62	17	must	must	AUX
anesthj-33	62	18	be	be	AUX
anesthj-33	62	19	individualized.6	individualized.6	PROPN
anesthj-33	62	20	most	most	ADJ
anesthj-33	62	21	mms	mms	NOUN
anesthj-33	62	22	follow	follow	VERB
anesthj-33	62	23	a	a	DET
anesthj-33	62	24	slow	slow	ADJ
anesthj-33	62	25	and	and	CCONJ
anesthj-33	62	26	progressive	progressive	ADJ
anesthj-33	62	27	course	course	NOUN
anesthj-33	62	28	;	;	PUNCT
anesthj-33	62	29	thus	thus	ADV
anesthj-33	62	30	,	,	PUNCT
anesthj-33	62	31	clinical	clinical	ADJ
anesthj-33	62	32	investigations	investigation	NOUN
anesthj-33	62	33	must	must	AUX
anesthj-33	62	34	be	be	AUX
anesthj-33	62	35	integrated	integrate	VERB
anesthj-33	62	36	by	by	ADP
anesthj-33	62	37	the	the	DET
anesthj-33	62	38	same	same	ADJ
anesthj-33	62	39	practitioner.4	practitioner.4	ADJ
anesthj-33	62	40	integrative	integrative	ADJ
anesthj-33	62	41	diagnosis	diagnosis	NOUN
anesthj-33	62	42	includes	include	VERB
anesthj-33	62	43	clinical	clinical	ADJ
anesthj-33	62	44	,	,	PUNCT
anesthj-33	62	45	electrophysiological	electrophysiological	ADJ
anesthj-33	62	46	,	,	PUNCT
anesthj-33	62	47	imaging	imaging	NOUN
anesthj-33	62	48	,	,	PUNCT
anesthj-33	62	49	biochemical	biochemical	ADJ
anesthj-33	62	50	,	,	PUNCT
anesthj-33	62	51	and	and	CCONJ
anesthj-33	62	52	genetic	genetic	ADJ
anesthj-33	62	53	investigations.5	investigations.5	ADJ
anesthj-33	62	54	genetic	genetic	ADJ
anesthj-33	62	55	studies	study	NOUN
anesthj-33	62	56	should	should	AUX
anesthj-33	62	57	be	be	AUX
anesthj-33	62	58	the	the	DET
anesthj-33	62	59	first	first	ADJ
anesthj-33	62	60	-	-	PUNCT
anesthj-33	62	61	line	line	NOUN
anesthj-33	62	62	method	method	NOUN
anesthj-33	62	63	for	for	ADP
anesthj-33	62	64	diagnosis	diagnosis	NOUN
anesthj-33	62	65	after	after	SCONJ
anesthj-33	62	66	clinical	clinical	ADJ
anesthj-33	62	67	features	feature	NOUN
anesthj-33	62	68	such	such	ADJ
anesthj-33	62	69	as	as	ADP
anesthj-33	62	70	diabetes	diabetes	NOUN
anesthj-33	62	71	,	,	PUNCT
anesthj-33	62	72	deafness	deafness	NOUN
anesthj-33	62	73	,	,	PUNCT
anesthj-33	62	74	and	and	CCONJ
anesthj-33	62	75	cardiomyopathy	cardiomyopathy	ADJ
anesthj-33	62	76	together	together	ADV
anesthj-33	62	77	raise	raise	VERB
anesthj-33	62	78	red	red	ADJ
anesthj-33	62	79	flags.6	flags.6	PROPN
anesthj-33	62	80	after	after	SCONJ
anesthj-33	62	81	genetic	genetic	ADJ
anesthj-33	62	82	studies	study	NOUN
anesthj-33	62	83	,	,	PUNCT
anesthj-33	62	84	blood	blood	NOUN
anesthj-33	62	85	,	,	PUNCT
anesthj-33	62	86	urine	urine	NOUN
anesthj-33	62	87	,	,	PUNCT
anesthj-33	62	88	and	and	CCONJ
anesthj-33	62	89	cerebrospinal	cerebrospinal	ADJ
anesthj-33	62	90	fluid	fluid	NOUN
anesthj-33	62	91	studies	study	NOUN
anesthj-33	62	92	should	should	AUX
anesthj-33	62	93	be	be	AUX
anesthj-33	62	94	conducted	conduct	VERB
anesthj-33	62	95	.	.	PUNCT
anesthj-33	63	1	if	if	SCONJ
anesthj-33	63	2	the	the	DET
anesthj-33	63	3	results	result	NOUN
anesthj-33	63	4	of	of	ADP
anesthj-33	63	5	these	these	PRON
anesthj-33	63	6	are	be	AUX
anesthj-33	63	7	negative	negative	ADJ
anesthj-33	63	8	,	,	PUNCT
anesthj-33	63	9	electrophysiological	electrophysiological	ADJ
anesthj-33	63	10	and	and	CCONJ
anesthj-33	63	11	neuroimaging	neuroimaging	ADJ
anesthj-33	63	12	studies	study	NOUN
anesthj-33	63	13	should	should	AUX
anesthj-33	63	14	be	be	AUX
anesthj-33	63	15	performed	perform	VERB
anesthj-33	63	16	in	in	ADP
anesthj-33	63	17	organs	organ	NOUN
anesthj-33	63	18	other	other	ADJ
anesthj-33	63	19	than	than	ADP
anesthj-33	63	20	the	the	DET
anesthj-33	63	21	nervous	nervous	ADJ
anesthj-33	63	22	system.6	system.6	NOUN
anesthj-33	63	23	last	last	ADJ
anesthj-33	63	24	,	,	PUNCT
anesthj-33	63	25	a	a	DET
anesthj-33	63	26	muscle	muscle	NOUN
anesthj-33	63	27	biopsy	biopsy	NOUN
anesthj-33	63	28	and	and	CCONJ
anesthj-33	63	29	biochemical	biochemical	ADJ
anesthj-33	63	30	investigations	investigation	NOUN
anesthj-33	63	31	should	should	AUX
anesthj-33	63	32	be	be	AUX
anesthj-33	63	33	conducted	conduct	VERB
anesthj-33	63	34	for	for	ADP
anesthj-33	63	35	diagnosis	diagnosis	NOUN
anesthj-33	63	36	if	if	SCONJ
anesthj-33	63	37	the	the	DET
anesthj-33	63	38	results	result	NOUN
anesthj-33	63	39	of	of	ADP
anesthj-33	63	40	all	all	DET
anesthj-33	63	41	other	other	ADJ
anesthj-33	63	42	testing	testing	NOUN
anesthj-33	63	43	are	be	AUX
anesthj-33	63	44	negative	negative	ADJ
anesthj-33	63	45	.	.	PUNCT
anesthj-33	64	1	these	these	DET
anesthj-33	64	2	investigations	investigation	NOUN
anesthj-33	64	3	can	can	AUX
anesthj-33	64	4	include	include	VERB
anesthj-33	64	5	electron	electron	NOUN
anesthj-33	64	6	microscopy	microscopy	NOUN
anesthj-33	64	7	and	and	CCONJ
anesthj-33	64	8	respiratory	respiratory	ADJ
anesthj-33	64	9	chain	chain	NOUN
anesthj-33	64	10	enzyme	enzyme	NOUN
anesthj-33	64	11	analysis	analysis	NOUN
anesthj-33	64	12	of	of	ADP
anesthj-33	64	13	the	the	DET
anesthj-33	64	14	muscle.6,7	muscle.6,7	NOUN
anesthj-33	64	15	there	there	PRON
anesthj-33	64	16	is	be	VERB
anesthj-33	64	17	no	no	DET
anesthj-33	64	18	known	know	VERB
anesthj-33	64	19	cure	cure	NOUN
anesthj-33	64	20	for	for	ADP
anesthj-33	64	21	melas	mela	NOUN
anesthj-33	64	22	.	.	PUNCT
anesthj-33	65	1	one	one	NUM
anesthj-33	65	2	study	study	NOUN
anesthj-33	65	3	showed	show	VERB
anesthj-33	65	4	marked	mark	VERB
anesthj-33	65	5	improvement	improvement	NOUN
anesthj-33	65	6	in	in	ADP
anesthj-33	65	7	stroke	stroke	NOUN
anesthj-33	65	8	-	-	PUNCT
anesthj-33	65	9	like	like	ADJ
anesthj-33	65	10	symptoms	symptom	NOUN
anesthj-33	65	11	after	after	ADP
anesthj-33	65	12	administration	administration	NOUN
anesthj-33	65	13	of	of	ADP
anesthj-33	65	14	l	l	NOUN
anesthj-33	65	15	-	-	NOUN
anesthj-33	65	16	arginine	arginine	NOUN
anesthj-33	65	17	,	,	PUNCT
anesthj-33	65	18	and	and	CCONJ
anesthj-33	65	19	more	more	ADV
anesthj-33	65	20	recently	recently	ADV
anesthj-33	65	21	,	,	PUNCT
anesthj-33	65	22	exercise	exercise	NOUN
anesthj-33	65	23	programs	program	NOUN
anesthj-33	65	24	have	have	AUX
anesthj-33	65	25	been	be	AUX
anesthj-33	65	26	shown	show	VERB
anesthj-33	65	27	to	to	PART
anesthj-33	65	28	prevent	prevent	VERB
anesthj-33	65	29	muscle	muscle	NOUN
anesthj-33	65	30	deconditioning.7	deconditioning.7	PROPN
anesthj-33	65	31	other	other	ADJ
anesthj-33	65	32	treatments	treatment	NOUN
anesthj-33	65	33	include	include	VERB
anesthj-33	65	34	nutritional	nutritional	ADJ
anesthj-33	65	35	support	support	NOUN
anesthj-33	65	36	with	with	ADP
anesthj-33	65	37	vitamins	vitamin	NOUN
anesthj-33	65	38	and	and	CCONJ
anesthj-33	65	39	cofactors	cofactor	NOUN
anesthj-33	65	40	;	;	PUNCT
anesthj-33	65	41	emotional	emotional	ADJ
anesthj-33	65	42	therapy	therapy	NOUN
anesthj-33	65	43	;	;	PUNCT
anesthj-33	65	44	physiologic	physiologic	ADJ
anesthj-33	65	45	stress	stress	NOUN
anesthj-33	65	46	reduction	reduction	NOUN
anesthj-33	65	47	,	,	PUNCT
anesthj-33	65	48	such	such	ADJ
anesthj-33	65	49	as	as	ADP
anesthj-33	65	50	environmental	environmental	ADJ
anesthj-33	65	51	temperature	temperature	NOUN
anesthj-33	65	52	control	control	NOUN
anesthj-33	65	53	;	;	PUNCT
anesthj-33	65	54	and	and	CCONJ
anesthj-33	65	55	reducing	reduce	VERB
anesthj-33	65	56	toxin	toxin	NOUN
anesthj-33	65	57	exposure	exposure	NOUN
anesthj-33	65	58	,	,	PUNCT
anesthj-33	65	59	such	such	ADJ
anesthj-33	65	60	as	as	ADP
anesthj-33	65	61	smoking.8	smoking.8	VERB
anesthj-33	65	62	the	the	DET
anesthj-33	65	63	clinical	clinical	ADJ
anesthj-33	65	64	presentation	presentation	NOUN
anesthj-33	65	65	of	of	ADP
anesthj-33	65	66	melas	melas	PROPN
anesthj-33	65	67	varies	vary	VERB
anesthj-33	65	68	tremendously	tremendously	ADV
anesthj-33	65	69	,	,	PUNCT
anesthj-33	65	70	and	and	CCONJ
anesthj-33	65	71	its	its	PRON
anesthj-33	65	72	incidence	incidence	NOUN
anesthj-33	65	73	is	be	AUX
anesthj-33	65	74	rare	rare	ADJ
anesthj-33	65	75	:	:	PUNCT
anesthj-33	65	76	12.5	12.5	NUM
anesthj-33	65	77	cases	case	NOUN
anesthj-33	65	78	per	per	ADP
anesthj-33	65	79	100,000.2	100,000.2	NUM
anesthj-33	65	80	most	most	ADV
anesthj-33	65	81	importantly	importantly	ADV
anesthj-33	65	82	for	for	ADP
anesthj-33	65	83	anesthesia	anesthesia	NOUN
anesthj-33	65	84	management	management	NOUN
anesthj-33	65	85	,	,	PUNCT
anesthj-33	65	86	the	the	DET
anesthj-33	65	87	respiratory	respiratory	ADJ
anesthj-33	65	88	chain	chain	NOUN
anesthj-33	65	89	is	be	AUX
anesthj-33	65	90	the	the	DET
anesthj-33	65	91	final	final	ADJ
anesthj-33	65	92	common	common	ADJ
anesthj-33	65	93	pathway	pathway	NOUN
anesthj-33	65	94	essential	essential	ADJ
anesthj-33	65	95	for	for	ADP
anesthj-33	65	96	aerobic	aerobic	ADJ
anesthj-33	65	97	metabolism	metabolism	NOUN
anesthj-33	65	98	.	.	PUNCT
anesthj-33	66	1	patients	patient	NOUN
anesthj-33	66	2	present	present	ADJ
anesthj-33	66	3	with	with	ADP
anesthj-33	66	4	symptoms	symptom	NOUN
anesthj-33	66	5	that	that	PRON
anesthj-33	66	6	are	be	AUX
anesthj-33	66	7	dependent	dependent	ADJ
anesthj-33	66	8	on	on	ADP
anesthj-33	66	9	tissues	tissue	NOUN
anesthj-33	66	10	requiring	require	VERB
anesthj-33	66	11	large	large	ADJ
anesthj-33	66	12	amounts	amount	NOUN
anesthj-33	66	13	of	of	ADP
anesthj-33	66	14	oxygen	oxygen	NOUN
anesthj-33	66	15	,	,	PUNCT
anesthj-33	66	16	such	such	ADJ
anesthj-33	66	17	as	as	ADP
anesthj-33	66	18	the	the	DET
anesthj-33	66	19	heart	heart	NOUN
anesthj-33	66	20	,	,	PUNCT
anesthj-33	66	21	central	central	ADJ
anesthj-33	66	22	nervous	nervous	ADJ
anesthj-33	66	23	system	system	NOUN
anesthj-33	66	24	,	,	PUNCT
anesthj-33	66	25	and	and	CCONJ
anesthj-33	66	26	muscle.1	muscle.1	PROPN
anesthj-33	66	27	according	accord	VERB
anesthj-33	66	28	to	to	ADP
anesthj-33	66	29	the	the	DET
anesthj-33	66	30	online	online	ADJ
anesthj-33	66	31	mendelian	mendelian	ADJ
anesthj-33	66	32	inheritance	inheritance	NOUN
anesthj-33	66	33	in	in	ADP
anesthj-33	66	34	man	man	NOUN
anesthj-33	66	35	database	database	NOUN
anesthj-33	66	36	,	,	PUNCT
anesthj-33	66	37	the	the	DET
anesthj-33	66	38	general	general	ADJ
anesthj-33	66	39	manifestations	manifestation	NOUN
anesthj-33	66	40	of	of	ADP
anesthj-33	66	41	melas	melas	PROPN
anesthj-33	66	42	range	range	NOUN
anesthj-33	66	43	from	from	ADP
anesthj-33	66	44	“	"	PUNCT
anesthj-33	66	45	seizures	seizure	NOUN
anesthj-33	66	46	,	,	PUNCT
anesthj-33	66	47	hemiparesis	hemiparesis	NOUN
anesthj-33	66	48	,	,	PUNCT
anesthj-33	66	49	hemianopsia	hemianopsia	PROPN
anesthj-33	66	50	,	,	PUNCT
anesthj-33	66	51	cortical	cortical	ADJ
anesthj-33	66	52	blindness	blindness	NOUN
anesthj-33	66	53	,	,	PUNCT
anesthj-33	66	54	to	to	ADP
anesthj-33	66	55	episodic	episodic	ADJ
anesthj-33	66	56	vomiting	vomiting	NOUN
anesthj-33	66	57	.	.	PUNCT
anesthj-33	66	58	”9	”9	PUNCT
anesthj-33	67	1	specific	specific	ADJ
anesthj-33	67	2	central	central	ADJ
anesthj-33	67	3	nervous	nervous	ADJ
anesthj-33	67	4	system	system	NOUN
anesthj-33	67	5	manifestations	manifestation	NOUN
anesthj-33	67	6	of	of	ADP
anesthj-33	67	7	melas	mela	NOUN
anesthj-33	67	8	can	can	AUX
anesthj-33	67	9	also	also	ADV
anesthj-33	67	10	include	include	VERB
anesthj-33	67	11	psychiatric	psychiatric	ADJ
anesthj-33	67	12	abnormalities	abnormality	NOUN
anesthj-33	67	13	,	,	PUNCT
anesthj-33	67	14	neuropsychological	neuropsychological	ADJ
anesthj-33	67	15	deficits	deficit	NOUN
anesthj-33	67	16	,	,	PUNCT
anesthj-33	67	17	stroke	stroke	NOUN
anesthj-33	67	18	-	-	PUNCT
anesthj-33	67	19	like	like	ADJ
anesthj-33	67	20	episodes	episode	NOUN
anesthj-33	67	21	,	,	PUNCT
anesthj-33	67	22	migraines	migraine	NOUN
anesthj-33	67	23	,	,	PUNCT
anesthj-33	67	24	epilepsy	epilepsy	NOUN
anesthj-33	67	25	,	,	PUNCT
anesthj-33	67	26	ataxia	ataxia	NOUN
anesthj-33	67	27	,	,	PUNCT
anesthj-33	67	28	and	and	CCONJ
anesthj-33	67	29	hypopituitarism.4	hypopituitarism.4	X
anesthj-33	67	30	mms	mms	NOUN
anesthj-33	67	31	can	can	AUX
anesthj-33	67	32	affect	affect	VERB
anesthj-33	67	33	a	a	DET
anesthj-33	67	34	single	single	ADJ
anesthj-33	67	35	organ	organ	NOUN
anesthj-33	67	36	system	system	NOUN
anesthj-33	67	37	or	or	CCONJ
anesthj-33	67	38	multiple	multiple	ADJ
anesthj-33	67	39	organ	organ	NOUN
anesthj-33	67	40	systems	system	NOUN
anesthj-33	67	41	as	as	ADP
anesthj-33	67	42	in	in	ADP
anesthj-33	67	43	melas	mela	NOUN
anesthj-33	67	44	.	.	PUNCT
anesthj-33	68	1	other	other	ADJ
anesthj-33	68	2	organ	organ	NOUN
anesthj-33	68	3	system	system	NOUN
anesthj-33	68	4	manifestations	manifestation	NOUN
anesthj-33	68	5	in	in	ADP
anesthj-33	68	6	melas	mela	NOUN
anesthj-33	68	7	can	can	AUX
anesthj-33	68	8	include	include	VERB
anesthj-33	68	9	cardiomyopathies	cardiomyopathy	NOUN
anesthj-33	68	10	,	,	PUNCT
anesthj-33	68	11	wolff	wolff	NOUN
anesthj-33	68	12	-	-	PUNCT
anesthj-33	68	13	parkinson	parkinson	NOUN
anesthj-33	68	14	-	-	PUNCT
anesthj-33	68	15	white	white	ADJ
anesthj-33	68	16	syndrome	syndrome	NOUN
anesthj-33	68	17	,	,	PUNCT
anesthj-33	68	18	cardiac	cardiac	ADJ
anesthj-33	68	19	conduction	conduction	NOUN
anesthj-33	68	20	pathway	pathway	NOUN
anesthj-33	68	21	blockade	blockade	NOUN
anesthj-33	68	22	,	,	PUNCT
anesthj-33	68	23	diabetes	diabetes	NOUN
anesthj-33	68	24	mellitus	mellitus	NOUN
anesthj-33	68	25	,	,	PUNCT
anesthj-33	68	26	sensorineural	sensorineural	ADJ
anesthj-33	68	27	hearing	hearing	NOUN
anesthj-33	68	28	loss	loss	NOUN
anesthj-33	68	29	,	,	PUNCT
anesthj-33	68	30	gastrointestinal	gastrointestinal	ADJ
anesthj-33	68	31	dysfunction	dysfunction	NOUN
anesthj-33	68	32	,	,	PUNCT
anesthj-33	68	33	malnutrition	malnutrition	NOUN
anesthj-33	68	34	,	,	PUNCT
anesthj-33	68	35	and	and	CCONJ
anesthj-33	68	36	muscle	muscle	NOUN
anesthj-33	69	1	wasting.2	wasting.2	PROPN
anesthj-33	69	2	preoperative	preoperative	NOUN
anesthj-33	69	3	evaluation	evaluation	NOUN
anesthj-33	69	4	of	of	ADP
anesthj-33	69	5	these	these	DET
anesthj-33	69	6	patients	patient	NOUN
anesthj-33	69	7	must	must	AUX
anesthj-33	69	8	include	include	VERB
anesthj-33	69	9	tests	test	NOUN
anesthj-33	69	10	specific	specific	ADJ
anesthj-33	69	11	to	to	ADP
anesthj-33	69	12	each	each	DET
anesthj-33	69	13	organ	organ	NOUN
anesthj-33	69	14	system	system	NOUN
anesthj-33	69	15	involved	involve	VERB
anesthj-33	69	16	.	.	PUNCT
anesthj-33	70	1	cardiomyopathy	cardiomyopathy	ADJ
anesthj-33	70	2	is	be	AUX
anesthj-33	70	3	most	most	ADV
anesthj-33	70	4	commonly	commonly	ADV
anesthj-33	70	5	present	present	ADJ
anesthj-33	70	6	in	in	ADP
anesthj-33	70	7	melas	mela	NOUN
anesthj-33	70	8	;	;	PUNCT
anesthj-33	70	9	thus	thus	ADV
anesthj-33	70	10	,	,	PUNCT
anesthj-33	70	11	a	a	DET
anesthj-33	70	12	12	12	NUM
anesthj-33	70	13	-	-	PUNCT
anesthj-33	70	14	lead	lead	NOUN
anesthj-33	70	15	electrocardiogram	electrocardiogram	NOUN
anesthj-33	70	16	and	and	CCONJ
anesthj-33	70	17	echocardiogram	echocardiogram	NOUN
anesthj-33	70	18	are	be	AUX
anesthj-33	70	19	paramount	paramount	ADJ
anesthj-33	70	20	.	.	PUNCT
anesthj-33	71	1	7	7	NUM
anesthj-33	71	2	the	the	DET
anesthj-33	71	3	patient	patient	NOUN
anesthj-33	71	4	in	in	ADP
anesthj-33	71	5	this	this	DET
anesthj-33	71	6	case	case	NOUN
anesthj-33	71	7	report	report	NOUN
anesthj-33	71	8	denied	deny	VERB
anesthj-33	71	9	any	any	DET
anesthj-33	71	10	cardiac	cardiac	ADJ
anesthj-33	71	11	history	history	NOUN
anesthj-33	71	12	and	and	CCONJ
anesthj-33	71	13	thus	thus	ADV
anesthj-33	71	14	this	this	PRON
anesthj-33	71	15	was	be	AUX
anesthj-33	71	16	not	not	PART
anesthj-33	71	17	obtained	obtain	VERB
anesthj-33	71	18	in	in	ADP
anesthj-33	71	19	the	the	DET
anesthj-33	71	20	preoperative	preoperative	ADJ
anesthj-33	71	21	evaluation	evaluation	NOUN
anesthj-33	71	22	but	but	CCONJ
anesthj-33	71	23	may	may	AUX
anesthj-33	71	24	have	have	AUX
anesthj-33	71	25	been	be	AUX
anesthj-33	71	26	helpful	helpful	ADJ
anesthj-33	71	27	in	in	ADP
anesthj-33	71	28	developing	develop	VERB
anesthj-33	71	29	an	an	DET
anesthj-33	71	30	appropriate	appropriate	ADJ
anesthj-33	71	31	anesthetic	anesthetic	ADJ
anesthj-33	71	32	plan	plan	NOUN
anesthj-33	71	33	.	.	PUNCT
anesthj-33	72	1	other	other	ADJ
anesthj-33	72	2	preoperative	preoperative	ADJ
anesthj-33	72	3	evaluation	evaluation	NOUN
anesthj-33	72	4	should	should	AUX
anesthj-33	72	5	include	include	VERB
anesthj-33	72	6	renal	renal	ADJ
anesthj-33	72	7	,	,	PUNCT
anesthj-33	72	8	hepatic	hepatic	NOUN
anesthj-33	72	9	,	,	PUNCT
anesthj-33	72	10	and	and	CCONJ
anesthj-33	72	11	blood	blood	NOUN
anesthj-33	72	12	glucose	glucose	NOUN
anesthj-33	72	13	tests.10	tests.10	NOUN
anesthj-33	72	14	a	a	DET
anesthj-33	72	15	full	full	ADJ
anesthj-33	72	16	neurologic	neurologic	ADJ
anesthj-33	72	17	evaluation	evaluation	NOUN
anesthj-33	72	18	should	should	AUX
anesthj-33	72	19	be	be	AUX
anesthj-33	72	20	conducted	conduct	VERB
anesthj-33	72	21	because	because	SCONJ
anesthj-33	72	22	melas	mela	NOUN
anesthj-33	72	23	patients	patient	NOUN
anesthj-33	72	24	can	can	AUX
anesthj-33	72	25	have	have	VERB
anesthj-33	72	26	stroke	stroke	NOUN
anesthj-33	72	27	-	-	PUNCT
anesthj-33	72	28	like	like	ADJ
anesthj-33	72	29	episodes	episode	NOUN
anesthj-33	72	30	mostly	mostly	ADV
anesthj-33	72	31	affecting	affect	VERB
anesthj-33	72	32	the	the	DET
anesthj-33	72	33	occipital	occipital	NOUN
anesthj-33	72	34	and	and	CCONJ
anesthj-33	72	35	parietal	parietal	ADJ
anesthj-33	72	36	lobes.4	lobes.4	PROPN
anesthj-33	72	37	exercise	exercise	NOUN
anesthj-33	72	38	tolerance	tolerance	NOUN
anesthj-33	72	39	,	,	PUNCT
anesthj-33	72	40	swallowing	swallow	VERB
anesthj-33	72	41	,	,	PUNCT
anesthj-33	72	42	and	and	CCONJ
anesthj-33	72	43	respiratory	respiratory	ADJ
anesthj-33	72	44	functions	function	NOUN
anesthj-33	72	45	are	be	AUX
anesthj-33	72	46	other	other	ADJ
anesthj-33	72	47	considerations	consideration	NOUN
anesthj-33	72	48	preoperatively	preoperatively	ADV
anesthj-33	72	49	,	,	PUNCT
anesthj-33	72	50	which	which	PRON
anesthj-33	72	51	may	may	AUX
anesthj-33	72	52	include	include	VERB
anesthj-33	72	53	chest	chest	NOUN
anesthj-33	72	54	x	x	NOUN
anesthj-33	72	55	-	-	NOUN
anesthj-33	72	56	ray	ray	NOUN
anesthj-33	72	57	imaging	imaging	NOUN
anesthj-33	72	58	and	and	CCONJ
anesthj-33	72	59	pulmonary	pulmonary	ADJ
anesthj-33	72	60	function	function	NOUN
anesthj-33	72	61	tests.10	tests.10	NOUN
anesthj-33	72	62	as	as	ADP
anesthj-33	72	63	a	a	DET
anesthj-33	72	64	result	result	NOUN
anesthj-33	72	65	of	of	ADP
anesthj-33	72	66	the	the	DET
anesthj-33	72	67	inability	inability	NOUN
anesthj-33	72	68	of	of	ADP
anesthj-33	72	69	pyruvate	pyruvate	NOUN
anesthj-33	72	70	to	to	PART
anesthj-33	72	71	be	be	AUX
anesthj-33	72	72	integrated	integrate	VERB
anesthj-33	72	73	into	into	ADP
anesthj-33	72	74	the	the	DET
anesthj-33	72	75	tricarboxylic	tricarboxylic	ADJ
anesthj-33	72	76	acid	acid	NOUN
anesthj-33	72	77	cycle	cycle	NOUN
anesthj-33	72	78	,	,	PUNCT
anesthj-33	72	79	melas	mela	NOUN
anesthj-33	72	80	patients	patient	NOUN
anesthj-33	72	81	have	have	AUX
anesthj-33	72	82	increased	increase	VERB
anesthj-33	72	83	susceptibility	susceptibility	NOUN
anesthj-33	72	84	to	to	ADP
anesthj-33	72	85	lactic	lactic	ADJ
anesthj-33	72	86	acidemia	acidemia	NOUN
anesthj-33	72	87	under	under	ADP
anesthj-33	72	88	increased	increase	VERB
anesthj-33	72	89	metabolic	metabolic	ADJ
anesthj-33	72	90	stress.4	stress.4	PROPN
anesthj-33	72	91	therefore	therefore	ADV
anesthj-33	72	92	,	,	PUNCT
anesthj-33	72	93	general	general	ADJ
anesthj-33	72	94	anesthesia	anesthesia	NOUN
anesthj-33	72	95	,	,	PUNCT
anesthj-33	72	96	medications	medication	NOUN
anesthj-33	72	97	used	use	VERB
anesthj-33	72	98	for	for	ADP
anesthj-33	72	99	anesthesia	anesthesia	NOUN
anesthj-33	72	100	,	,	PUNCT
anesthj-33	72	101	and	and	CCONJ
anesthj-33	72	102	surgery	surgery	NOUN
anesthj-33	72	103	can	can	AUX
anesthj-33	72	104	cause	cause	VERB
anesthj-33	72	105	deterioration	deterioration	NOUN
anesthj-33	72	106	of	of	ADP
anesthj-33	72	107	clinical	clinical	ADJ
anesthj-33	72	108	manifestations	manifestation	NOUN
anesthj-33	72	109	in	in	ADP
anesthj-33	72	110	mms	mms	NOUN
anesthj-33	72	111	because	because	SCONJ
anesthj-33	72	112	of	of	ADP
anesthj-33	72	113	increased	increase	VERB
anesthj-33	72	114	metabolic	metabolic	NOUN
anesthj-33	72	115	stress.4	stress.4	PROPN
anesthj-33	72	116	other	other	ADJ
anesthj-33	72	117	circumstances	circumstance	NOUN
anesthj-33	72	118	that	that	PRON
anesthj-33	72	119	can	can	AUX
anesthj-33	72	120	cause	cause	VERB
anesthj-33	72	121	a	a	DET
anesthj-33	72	122	metabolic	metabolic	NOUN
anesthj-33	72	123	burden	burden	NOUN
anesthj-33	72	124	in	in	ADP
anesthj-33	72	125	these	these	DET
anesthj-33	72	126	patients	patient	NOUN
anesthj-33	72	127	and	and	CCONJ
anesthj-33	72	128	should	should	AUX
anesthj-33	72	129	be	be	AUX
anesthj-33	72	130	avoided	avoid	VERB
anesthj-33	72	131	or	or	CCONJ
anesthj-33	72	132	decreased	decrease	VERB
anesthj-33	72	133	include	include	VERB
anesthj-33	72	134	prolonged	prolonged	ADJ
anesthj-33	72	135	fasting	fasting	NOUN
anesthj-33	72	136	,	,	PUNCT
anesthj-33	72	137	hypoglycemia	hypoglycemia	NOUN
anesthj-33	72	138	,	,	PUNCT
anesthj-33	72	139	postoperative	postoperative	ADJ
anesthj-33	72	140	nausea	nausea	NOUN
anesthj-33	72	141	and	and	CCONJ
anesthj-33	72	142	vomiting	vomiting	NOUN
anesthj-33	72	143	,	,	PUNCT
anesthj-33	72	144	hypothermia	hypothermia	NOUN
anesthj-33	72	145	,	,	PUNCT
anesthj-33	72	146	prolonged	prolonged	ADJ
anesthj-33	72	147	tourniquets	tourniquet	NOUN
anesthj-33	72	148	,	,	PUNCT
anesthj-33	72	149	acidosis	acidosis	NOUN
anesthj-33	72	150	,	,	PUNCT
anesthj-33	72	151	and	and	CCONJ
anesthj-33	72	152	hypovolemia.5	hypovolemia.5	ADP
anesthj-33	72	153	choice	choice	NOUN
anesthj-33	72	154	of	of	ADP
anesthj-33	72	155	fluids	fluid	NOUN
anesthj-33	72	156	in	in	ADP
anesthj-33	72	157	melas	mela	NOUN
anesthj-33	72	158	patients	patient	NOUN
anesthj-33	72	159	remains	remain	VERB
anesthj-33	72	160	controversial	controversial	ADJ
anesthj-33	72	161	because	because	SCONJ
anesthj-33	72	162	whereas	whereas	SCONJ
anesthj-33	72	163	hypoglycemia	hypoglycemia	NOUN
anesthj-33	72	164	can	can	AUX
anesthj-33	72	165	cause	cause	VERB
anesthj-33	72	166	increased	increase	VERB
anesthj-33	72	167	metabolic	metabolic	NOUN
anesthj-33	72	168	burden	burden	NOUN
anesthj-33	72	169	,	,	PUNCT
anesthj-33	72	170	glucose	glucose	NOUN
anesthj-33	72	171	-	-	PUNCT
anesthj-33	72	172	containing	contain	VERB
anesthj-33	72	173	fluids	fluid	NOUN
anesthj-33	72	174	may	may	AUX
anesthj-33	72	175	not	not	PART
anesthj-33	72	176	be	be	AUX
anesthj-33	72	177	optimal	optimal	ADJ
anesthj-33	72	178	for	for	ADP
anesthj-33	72	179	avoidance	avoidance	NOUN
anesthj-33	72	180	of	of	ADP
anesthj-33	72	181	seizures.5	seizures.5	PROPN
anesthj-33	72	182	in	in	ADP
anesthj-33	72	183	one	one	NUM
anesthj-33	72	184	case	case	NOUN
anesthj-33	72	185	report	report	NOUN
anesthj-33	72	186	,	,	PUNCT
anesthj-33	72	187	glucose	glucose	NOUN
anesthj-33	72	188	-	-	PUNCT
anesthj-33	72	189	containing	contain	VERB
anesthj-33	72	190	fluid	fluid	NOUN
anesthj-33	72	191	was	be	AUX
anesthj-33	72	192	given	give	VERB
anesthj-33	72	193	intraoperatively	intraoperatively	ADV
anesthj-33	72	194	in	in	ADP
anesthj-33	72	195	a	a	DET
anesthj-33	72	196	melas	melas	NOUN
anesthj-33	72	197	patient	patient	NOUN
anesthj-33	72	198	without	without	ADP
anesthj-33	72	199	adverse	adverse	ADJ
anesthj-33	72	200	effect.11	effect.11	PROPN
anesthj-33	72	201	also	also	ADV
anesthj-33	72	202	,	,	PUNCT
anesthj-33	72	203	owing	owe	VERB
anesthj-33	72	204	to	to	ADP
anesthj-33	72	205	the	the	DET
anesthj-33	72	206	predisposition	predisposition	NOUN
anesthj-33	72	207	of	of	ADP
anesthj-33	72	208	these	these	DET
anesthj-33	72	209	patients	patient	NOUN
anesthj-33	72	210	to	to	ADP
anesthj-33	72	211	lactic	lactic	ADJ
anesthj-33	72	212	acidosis	acidosis	NOUN
anesthj-33	72	213	,	,	PUNCT
anesthj-33	72	214	lactated	lactated	ADJ
anesthj-33	72	215	ringer	ringer	NOUN
anesthj-33	72	216	’s	’s	PART
anesthj-33	72	217	solution	solution	NOUN
anesthj-33	72	218	may	may	AUX
anesthj-33	72	219	not	not	PART
anesthj-33	72	220	have	have	AUX
anesthj-33	72	221	been	be	AUX
anesthj-33	72	222	the	the	DET
anesthj-33	72	223	best	good	ADJ
anesthj-33	72	224	choice	choice	NOUN
anesthj-33	72	225	of	of	ADP
anesthj-33	72	226	intravenous	intravenous	ADJ
anesthj-33	72	227	fluids	fluid	NOUN
anesthj-33	72	228	in	in	ADP
anesthj-33	72	229	this	this	DET
anesthj-33	72	230	patient.11,12	patient.11,12	NOUN
anesthj-33	72	231	according	accord	VERB
anesthj-33	72	232	to	to	ADP
anesthj-33	72	233	the	the	DET
anesthj-33	72	234	malignant	malignant	ADJ
anesthj-33	72	235	hyperthermia	hyperthermia	NOUN
anesthj-33	72	236	association	association	NOUN
anesthj-33	72	237	of	of	ADP
anesthj-33	72	238	the	the	DET
anesthj-33	72	239	united	united	PROPN
anesthj-33	72	240	states	states	PROPN
anesthj-33	72	241	(	(	PUNCT
anesthj-33	72	242	mhaus	mhaus	PROPN
anesthj-33	72	243	)	)	PUNCT
anesthj-33	72	244	,	,	PUNCT
anesthj-33	72	245	the	the	DET
anesthj-33	72	246	first	first	ADJ
anesthj-33	72	247	association	association	NOUN
anesthj-33	72	248	between	between	ADP
anesthj-33	72	249	mms	mms	PROPN
anesthj-33	72	250	and	and	CCONJ
anesthj-33	72	251	malignant	malignant	ADJ
anesthj-33	72	252	hyperthermia	hyperthermia	NOUN
anesthj-33	72	253	was	be	AUX
anesthj-33	72	254	suggested	suggest	VERB
anesthj-33	72	255	owing	owe	VERB
anesthj-33	72	256	to	to	ADP
anesthj-33	72	257	the	the	DET
anesthj-33	72	258	similar	similar	ADJ
anesthj-33	72	259	presenting	present	VERB
anesthj-33	72	260	clinical	clinical	ADJ
anesthj-33	72	261	features	feature	NOUN
anesthj-33	72	262	,	,	PUNCT
anesthj-33	72	263	such	such	ADJ
anesthj-33	72	264	as	as	ADP
anesthj-33	72	265	acidosis.13	acidosis.13	NOUN
anesthj-33	72	266	however	however	ADV
anesthj-33	72	267	,	,	PUNCT
anesthj-33	72	268	recommendations	recommendation	NOUN
anesthj-33	72	269	from	from	ADP
anesthj-33	72	270	mhaus	mhaus	PROPN
anesthj-33	72	271	state	state	PROPN
anesthj-33	72	272	that	that	DET
anesthj-33	72	273	avoidance	avoidance	NOUN
anesthj-33	72	274	of	of	ADP
anesthj-33	72	275	volatile	volatile	ADJ
anesthj-33	72	276	anesthetics	anesthetic	NOUN
anesthj-33	72	277	is	be	AUX
anesthj-33	72	278	not	not	PART
anesthj-33	72	279	necessary	necessary	ADJ
anesthj-33	72	280	because	because	SCONJ
anesthj-33	72	281	of	of	ADP
anesthj-33	72	282	no	no	DET
anesthj-33	72	283	increased	increase	VERB
anesthj-33	72	284	susceptibility	susceptibility	NOUN
anesthj-33	72	285	of	of	ADP
anesthj-33	72	286	patients	patient	NOUN
anesthj-33	72	287	with	with	ADP
anesthj-33	72	288	mms	mms	NOUN
anesthj-33	72	289	to	to	PART
anesthj-33	72	290	malignant	malignant	VERB
anesthj-33	72	291	hyperthermia.13	hyperthermia.13	PROPN
anesthj-33	72	292	avoidance	avoidance	NOUN
anesthj-33	72	293	of	of	ADP
anesthj-33	72	294	succinylcholine	succinylcholine	NOUN
anesthj-33	72	295	has	have	AUX
anesthj-33	72	296	been	be	AUX
anesthj-33	72	297	discussed	discuss	VERB
anesthj-33	72	298	because	because	SCONJ
anesthj-33	72	299	of	of	ADP
anesthj-33	72	300	one	one	NUM
anesthj-33	72	301	case	case	NOUN
anesthj-33	72	302	report	report	NOUN
anesthj-33	72	303	in	in	ADP
anesthj-33	72	304	1985	1985	NUM
anesthj-33	72	305	in	in	ADP
anesthj-33	72	306	which	which	PRON
anesthj-33	72	307	life	life	NOUN
anesthj-33	72	308	-	-	PUNCT
anesthj-33	72	309	threatening	threaten	VERB
anesthj-33	72	310	hyperkalemia	hyperkalemia	NOUN
anesthj-33	72	311	occurred	occur	VERB
anesthj-33	72	312	in	in	ADP
anesthj-33	72	313	a	a	DET
anesthj-33	72	314	patient	patient	NOUN
anesthj-33	72	315	with	with	ADP
anesthj-33	72	316	mitochondrial	mitochondrial	ADJ
anesthj-33	72	317	dysfunction	dysfunction	NOUN
anesthj-33	72	318	after	after	ADP
anesthj-33	72	319	its	its	PRON
anesthj-33	72	320	administration.13	administration.13	NOUN
anesthj-33	72	321	however	however	ADV
anesthj-33	72	322	,	,	PUNCT
anesthj-33	72	323	just	just	ADV
anesthj-33	72	324	as	as	SCONJ
anesthj-33	72	325	mhaus	mhaus	NOUN
anesthj-33	72	326	suggests	suggest	VERB
anesthj-33	72	327	,	,	PUNCT
anesthj-33	72	328	no	no	DET
anesthj-33	72	329	definitive	definitive	ADJ
anesthj-33	72	330	genetic	genetic	ADJ
anesthj-33	72	331	link	link	NOUN
anesthj-33	72	332	has	have	AUX
anesthj-33	72	333	been	be	AUX
anesthj-33	72	334	shown	show	VERB
anesthj-33	72	335	between	between	ADP
anesthj-33	72	336	malignant	malignant	ADJ
anesthj-33	72	337	hyperthermia	hyperthermia	NOUN
anesthj-33	72	338	and	and	CCONJ
anesthj-33	72	339	mitochondrial	mitochondrial	ADJ
anesthj-33	72	340	diseases	disease	NOUN
anesthj-33	72	341	such	such	ADJ
anesthj-33	72	342	as	as	ADP
anesthj-33	72	343	melas.14	melas.14	NOUN
anesthj-33	72	344	only	only	ADV
anesthj-33	72	345	central	central	ADJ
anesthj-33	72	346	core	core	NOUN
anesthj-33	72	347	disease	disease	NOUN
anesthj-33	72	348	,	,	PUNCT
anesthj-33	72	349	multiminicore	multiminicore	NOUN
anesthj-33	72	350	disease	disease	NOUN
anesthj-33	72	351	,	,	PUNCT
anesthj-33	72	352	and	and	CCONJ
anesthj-33	72	353	king	king	NOUN
anesthj-33	72	354	-	-	PUNCT
anesthj-33	72	355	denborough	denborough	NOUN
anesthj-33	72	356	syndrome	syndrome	NOUN
anesthj-33	72	357	have	have	VERB
anesthj-33	72	358	a	a	DET
anesthj-33	72	359	more	more	ADV
anesthj-33	72	360	definitive	definitive	ADJ
anesthj-33	72	361	link	link	NOUN
anesthj-33	72	362	to	to	ADP
anesthj-33	72	363	malignant	malignant	ADJ
anesthj-33	72	364	hyperthermia.14	hyperthermia.14	NOUN
anesthj-33	72	365	the	the	DET
anesthj-33	72	366	use	use	NOUN
anesthj-33	72	367	of	of	ADP
anesthj-33	72	368	succinylcholine	succinylcholine	NOUN
anesthj-33	72	369	in	in	ADP
anesthj-33	72	370	melas	melas	PROPN
anesthj-33	72	371	patients	patient	NOUN
anesthj-33	72	372	with	with	ADP
anesthj-33	72	373	muscle	muscle	NOUN
anesthj-33	72	374	wasting	waste	VERB
anesthj-33	72	375	can	can	AUX
anesthj-33	72	376	still	still	ADV
anesthj-33	72	377	predispose	predispose	VERB
anesthj-33	72	378	patients	patient	NOUN
anesthj-33	72	379	to	to	ADP
anesthj-33	72	380	hyperkalemia	hyperkalemia	NOUN
anesthj-33	72	381	,	,	PUNCT
anesthj-33	72	382	but	but	CCONJ
anesthj-33	72	383	not	not	PART
anesthj-33	72	384	as	as	ADP
anesthj-33	72	385	a	a	DET
anesthj-33	72	386	result	result	NOUN
anesthj-33	72	387	of	of	ADP
anesthj-33	72	388	the	the	DET
anesthj-33	72	389	disease	disease	NOUN
anesthj-33	72	390	itself	itself	PRON
anesthj-33	72	391	.	.	PUNCT
anesthj-33	73	1	most	most	ADJ
anesthj-33	73	2	of	of	ADP
anesthj-33	73	3	the	the	DET
anesthj-33	73	4	evidence	evidence	NOUN
anesthj-33	73	5	in	in	ADP
anesthj-33	73	6	the	the	DET
anesthj-33	73	7	literature	literature	NOUN
anesthj-33	73	8	is	be	AUX
anesthj-33	73	9	based	base	VERB
anesthj-33	73	10	on	on	ADP
anesthj-33	73	11	clinical	clinical	ADJ
anesthj-33	73	12	case	case	NOUN
anesthj-33	73	13	reports	report	VERB
anesthj-33	73	14	.	.	PUNCT
anesthj-33	74	1	various	various	ADJ
anesthj-33	74	2	anesthetic	anesthetic	ADJ
anesthj-33	74	3	techniques	technique	NOUN
anesthj-33	74	4	have	have	AUX
anesthj-33	74	5	been	be	AUX
anesthj-33	74	6	used	use	VERB
anesthj-33	74	7	in	in	ADP
anesthj-33	74	8	melas	mela	NOUN
anesthj-33	74	9	patients	patient	NOUN
anesthj-33	74	10	without	without	ADP
anesthj-33	74	11	adverse	adverse	ADJ
anesthj-33	74	12	effects.15	effects.15	NOUN
anesthj-33	74	13	in	in	ADP
anesthj-33	74	14	a	a	DET
anesthj-33	74	15	retrospective	retrospective	ADJ
anesthj-33	74	16	review	review	NOUN
anesthj-33	74	17	of	of	ADP
anesthj-33	74	18	64	64	NUM
anesthj-33	74	19	patients	patient	NOUN
anesthj-33	74	20	with	with	ADP
anesthj-33	74	21	mitochondrial	mitochondrial	ADJ
anesthj-33	74	22	disease	disease	NOUN
anesthj-33	74	23	(	(	PUNCT
anesthj-33	74	24	6	6	NUM
anesthj-33	74	25	cases	case	NOUN
anesthj-33	74	26	of	of	ADP
anesthj-33	74	27	melas	mela	NOUN
anesthj-33	74	28	)	)	PUNCT
anesthj-33	74	29	,	,	PUNCT
anesthj-33	74	30	a	a	DET
anesthj-33	74	31	variety	variety	NOUN
anesthj-33	74	32	of	of	ADP
anesthj-33	74	33	anesthetic	anesthetic	ADJ
anesthj-33	74	34	techniques	technique	NOUN
anesthj-33	74	35	were	be	AUX
anesthj-33	74	36	used	use	VERB
anesthj-33	74	37	with	with	ADP
anesthj-33	74	38	no	no	DET
anesthj-33	74	39	significant	significant	ADJ
anesthj-33	74	40	events	event	NOUN
anesthj-33	74	41	such	such	ADJ
anesthj-33	74	42	as	as	ADP
anesthj-33	74	43	unanticipated	unanticipated	ADJ
anesthj-33	74	44	hospital	hospital	NOUN
anesthj-33	74	45	admission	admission	NOUN
anesthj-33	74	46	,	,	PUNCT
anesthj-33	74	47	cardiac	cardiac	ADJ
anesthj-33	74	48	arrest	arrest	NOUN
anesthj-33	74	49	,	,	PUNCT
anesthj-33	74	50	hypothermia	hypothermia	NOUN
anesthj-33	74	51	,	,	PUNCT
anesthj-33	74	52	hyperthermia	hyperthermia	NOUN
anesthj-33	74	53	,	,	PUNCT
anesthj-33	74	54	prolonged	prolong	VERB
anesthj-33	74	55	post	post	ADJ
anesthj-33	74	56	-	-	ADJ
anesthj-33	74	57	anesthesia	anesthesia	ADJ
anesthj-33	74	58	stay	stay	NOUN
anesthj-33	74	59	,	,	PUNCT
anesthj-33	74	60	increased	increase	VERB
anesthj-33	74	61	lactic	lactic	ADJ
anesthj-33	74	62	acidosis	acidosis	NOUN
anesthj-33	74	63	,	,	PUNCT
anesthj-33	74	64	or	or	CCONJ
anesthj-33	74	65	metabolic	metabolic	NOUN
anesthj-33	74	66	decompensation	decompensation	NOUN
anesthj-33	74	67	after	after	ADP
anesthj-33	74	68	exposure.15	exposure.15	PROPN
anesthj-33	74	69	these	these	DET
anesthj-33	74	70	techniques	technique	NOUN
anesthj-33	74	71	included	include	VERB
anesthj-33	74	72	volatile	volatile	ADJ
anesthj-33	74	73	anesthetic	anesthetic	ADJ
anesthj-33	74	74	gases	gas	NOUN
anesthj-33	74	75	,	,	PUNCT
anesthj-33	74	76	neuromuscular	neuromuscular	ADJ
anesthj-33	74	77	blockers	blocker	NOUN
anesthj-33	74	78	,	,	PUNCT
anesthj-33	74	79	and	and	CCONJ
anesthj-33	74	80	analgesics.15	analgesics.15	NOUN
anesthj-33	74	81	in	in	ADP
anesthj-33	74	82	yet	yet	ADV
anesthj-33	74	83	another	another	DET
anesthj-33	74	84	case	case	NOUN
anesthj-33	74	85	series	series	NOUN
anesthj-33	74	86	review	review	NOUN
anesthj-33	74	87	of	of	ADP
anesthj-33	74	88	patients	patient	NOUN
anesthj-33	74	89	with	with	ADP
anesthj-33	74	90	mitochondrial	mitochondrial	ADJ
anesthj-33	74	91	cytopathies	cytopathie	NOUN
anesthj-33	74	92	,	,	PUNCT
anesthj-33	74	93	all	all	DET
anesthj-33	74	94	39	39	NUM
anesthj-33	74	95	patients	patient	NOUN
anesthj-33	74	96	undergoing	undergo	VERB
anesthj-33	74	97	surgery	surgery	NOUN
anesthj-33	74	98	were	be	AUX
anesthj-33	74	99	anesthetized	anesthetize	VERB
anesthj-33	74	100	with	with	ADP
anesthj-33	74	101	inhalational	inhalational	ADJ
anesthj-33	74	102	gases	gas	NOUN
anesthj-33	74	103	,	,	PUNCT
anesthj-33	74	104	local	local	ADJ
anesthj-33	74	105	anesthesia	anesthesia	NOUN
anesthj-33	74	106	,	,	PUNCT
anesthj-33	74	107	sedation	sedation	NOUN
anesthj-33	74	108	,	,	PUNCT
anesthj-33	74	109	and	and	CCONJ
anesthj-33	74	110	general	general	ADJ
anesthj-33	74	111	balanced	balance	VERB
anesthj-33	74	112	anesthesia	anesthesia	NOUN
anesthj-33	74	113	without	without	ADP
anesthj-33	74	114	any	any	DET
anesthj-33	74	115	complications	complication	NOUN
anesthj-33	74	116	,	,	PUNCT
anesthj-33	74	117	which	which	PRON
anesthj-33	74	118	suggested	suggest	VERB
anesthj-33	74	119	that	that	SCONJ
anesthj-33	74	120	the	the	DET
anesthj-33	74	121	routine	routine	ADJ
anesthj-33	74	122	use	use	NOUN
anesthj-33	74	123	of	of	ADP
anesthj-33	74	124	intravenous	intravenous	ADJ
anesthj-33	74	125	or	or	CCONJ
anesthj-33	74	126	inhaled	inhale	VERB
anesthj-33	74	127	anesthesia	anesthesia	PROPN
anesthj-33	74	128	did	do	AUX
anesthj-33	74	129	not	not	PART
anesthj-33	74	130	influence	influence	VERB
anesthj-33	74	131	the	the	DET
anesthj-33	74	132	outcome.16	outcome.16	NOUN
anesthj-33	74	133	in	in	ADP
anesthj-33	74	134	a	a	DET
anesthj-33	74	135	pediatric	pediatric	ADJ
anesthj-33	74	136	case	case	NOUN
anesthj-33	74	137	series	series	NOUN
anesthj-33	74	138	review	review	NOUN
anesthj-33	74	139	by	by	ADP
anesthj-33	74	140	footitt	footitt	PROPN
anesthj-33	74	141	et	et	PROPN
anesthj-33	74	142	al	al	PROPN
anesthj-33	74	143	,	,	PUNCT
anesthj-33	74	144	38	38	NUM
anesthj-33	74	145	patients	patient	NOUN
anesthj-33	74	146	with	with	ADP
anesthj-33	74	147	confirmed	confirm	VERB
anesthj-33	74	148	mitochondrial	mitochondrial	ADJ
anesthj-33	74	149	disease	disease	NOUN
anesthj-33	74	150	underwent	undergo	VERB
anesthj-33	74	151	69	69	NUM
anesthj-33	74	152	cases	case	NOUN
anesthj-33	74	153	of	of	ADP
anesthj-33	74	154	general	general	ADJ
anesthj-33	74	155	anesthesia.17	anesthesia.17	ADJ
anesthj-33	74	156	anesthetic	anesthetic	NOUN
anesthj-33	74	157	agents	agent	NOUN
anesthj-33	74	158	included	include	VERB
anesthj-33	74	159	sevoflurane	sevoflurane	NOUN
anesthj-33	74	160	,	,	PUNCT
anesthj-33	74	161	propofol	propofol	NOUN
anesthj-33	74	162	,	,	PUNCT
anesthj-33	74	163	midazolam	midazolam	NOUN
anesthj-33	74	164	,	,	PUNCT
anesthj-33	74	165	fentanyl	fentanyl	NOUN
anesthj-33	74	166	,	,	PUNCT
anesthj-33	74	167	rocuronium	rocuronium	NOUN
anesthj-33	74	168	,	,	PUNCT
anesthj-33	74	169	atracurium	atracurium	NOUN
anesthj-33	74	170	,	,	PUNCT
anesthj-33	74	171	alfentanil	alfentanil	ADJ
anesthj-33	74	172	,	,	PUNCT
anesthj-33	74	173	anesthesia	anesthesia	PROPN
anesthj-33	74	174	ejournal	ejournal	PROPN
anesthj-33	74	175	www.anesthesiaejournal.com	www.anesthesiaejournal.com	PROPN
anesthj-33	74	176	volume	volume	NOUN
anesthj-33	74	177	4	4	NUM
anesthj-33	74	178	issue	issue	NOUN
anesthj-33	74	179	1	1	NUM
anesthj-33	74	180	2016	2016	NUM
anesthj-33	74	181	page	page	NOUN
anesthj-33	74	182	22	22	NUM
anesthj-33	74	183	anesthesia	anesthesia	PROPN
anesthj-33	74	184	ejournal	ejournal	PROPN
anesthj-33	74	185	www.anesthesiaejournal.com	www.anesthesiaejournal.com	PROPN
anesthj-33	74	186	volume	volume	NOUN
anesthj-33	74	187	4	4	NUM
anesthj-33	74	188	issue	issue	NOUN
anesthj-33	74	189	1	1	NUM
anesthj-33	74	190	2016	2016	NUM
anesthj-33	74	191	page	page	NOUN
anesthj-33	74	192	23	23	NUM
anesthj-33	74	193	and	and	CCONJ
anesthj-33	74	194	even	even	ADV
anesthj-33	74	195	2	2	NUM
anesthj-33	74	196	cases	case	NOUN
anesthj-33	74	197	of	of	ADP
anesthj-33	74	198	use	use	NOUN
anesthj-33	74	199	of	of	ADP
anesthj-33	74	200	succinylcholine	succinylcholine	NOUN
anesthj-33	74	201	with	with	ADP
anesthj-33	74	202	no	no	DET
anesthj-33	74	203	adverse	adverse	ADJ
anesthj-33	74	204	events	event	NOUN
anesthj-33	74	205	noted	note	VERB
anesthj-33	74	206	intraoperatively.17	intraoperatively.17	ADJ
anesthj-33	74	207	three	three	NUM
anesthj-33	74	208	adverse	adverse	ADJ
anesthj-33	74	209	events	event	NOUN
anesthj-33	74	210	were	be	AUX
anesthj-33	74	211	reported	report	VERB
anesthj-33	74	212	,	,	PUNCT
anesthj-33	74	213	none	none	NOUN
anesthj-33	74	214	in	in	ADP
anesthj-33	74	215	melas	mela	NOUN
anesthj-33	74	216	patients	patient	NOUN
anesthj-33	74	217	,	,	PUNCT
anesthj-33	74	218	which	which	PRON
anesthj-33	74	219	included	include	VERB
anesthj-33	74	220	postoperative	postoperative	ADJ
anesthj-33	74	221	hypovolemia	hypovolemia	NOUN
anesthj-33	74	222	,	,	PUNCT
anesthj-33	74	223	renal	renal	ADJ
anesthj-33	74	224	impairment	impairment	NOUN
anesthj-33	74	225	,	,	PUNCT
anesthj-33	74	226	respiratory	respiratory	ADJ
anesthj-33	74	227	failure	failure	NOUN
anesthj-33	74	228	,	,	PUNCT
anesthj-33	74	229	and	and	CCONJ
anesthj-33	74	230	metabolic	metabolic	NOUN
anesthj-33	74	231	acidosis.17	acidosis.17	NOUN
anesthj-33	74	232	even	even	ADV
anesthj-33	74	233	though	though	SCONJ
anesthj-33	74	234	there	there	PRON
anesthj-33	74	235	has	have	AUX
anesthj-33	74	236	been	be	AUX
anesthj-33	74	237	wide	wide	ADJ
anesthj-33	74	238	documentation	documentation	NOUN
anesthj-33	74	239	of	of	ADP
anesthj-33	74	240	the	the	DET
anesthj-33	74	241	safety	safety	NOUN
anesthj-33	74	242	of	of	ADP
anesthj-33	74	243	multiple	multiple	ADJ
anesthj-33	74	244	intravenous	intravenous	ADJ
anesthj-33	74	245	anesthetics	anesthetic	NOUN
anesthj-33	74	246	,	,	PUNCT
anesthj-33	74	247	careful	careful	ADJ
anesthj-33	74	248	consideration	consideration	NOUN
anesthj-33	74	249	must	must	AUX
anesthj-33	74	250	still	still	ADV
anesthj-33	74	251	be	be	AUX
anesthj-33	74	252	taken	take	VERB
anesthj-33	74	253	.	.	PUNCT
anesthj-33	75	1	although	although	SCONJ
anesthj-33	75	2	there	there	PRON
anesthj-33	75	3	are	be	VERB
anesthj-33	75	4	no	no	DET
anesthj-33	75	5	documented	document	VERB
anesthj-33	75	6	cases	case	NOUN
anesthj-33	75	7	of	of	ADP
anesthj-33	75	8	adverse	adverse	ADJ
anesthj-33	75	9	effects	effect	NOUN
anesthj-33	75	10	from	from	ADP
anesthj-33	75	11	analgesics	analgesic	NOUN
anesthj-33	75	12	in	in	ADP
anesthj-33	75	13	melas	mela	NOUN
anesthj-33	75	14	patients	patient	NOUN
anesthj-33	75	15	,	,	PUNCT
anesthj-33	75	16	these	these	DET
anesthj-33	75	17	patients	patient	NOUN
anesthj-33	75	18	may	may	AUX
anesthj-33	75	19	be	be	AUX
anesthj-33	75	20	at	at	ADP
anesthj-33	75	21	risk	risk	NOUN
anesthj-33	75	22	for	for	ADP
anesthj-33	75	23	decreased	decrease	VERB
anesthj-33	75	24	ventilatory	ventilatory	ADJ
anesthj-33	75	25	response	response	NOUN
anesthj-33	75	26	to	to	ADP
anesthj-33	75	27	hypoxia	hypoxia	NOUN
anesthj-33	75	28	and	and	CCONJ
anesthj-33	75	29	hypercarbia	hypercarbia	NOUN
anesthj-33	75	30	and	and	CCONJ
anesthj-33	75	31	may	may	AUX
anesthj-33	75	32	suffer	suffer	VERB
anesthj-33	75	33	respiratory	respiratory	ADJ
anesthj-33	75	34	compromise	compromise	NOUN
anesthj-33	75	35	from	from	ADP
anesthj-33	75	36	muscle	muscle	NOUN
anesthj-33	75	37	wasting	wasting	NOUN
anesthj-33	75	38	,	,	PUNCT
anesthj-33	75	39	and	and	CCONJ
anesthj-33	75	40	thus	thus	ADV
anesthj-33	75	41	careful	careful	ADJ
anesthj-33	75	42	titration	titration	NOUN
anesthj-33	75	43	of	of	ADP
anesthj-33	75	44	analgesics	analgesic	NOUN
anesthj-33	75	45	is	be	AUX
anesthj-33	75	46	necessary.18	necessary.18	ADJ
anesthj-33	75	47	propofol	propofol	NOUN
anesthj-33	75	48	has	have	AUX
anesthj-33	75	49	been	be	AUX
anesthj-33	75	50	implicated	implicate	VERB
anesthj-33	75	51	in	in	ADP
anesthj-33	75	52	propofol	propofol	ADJ
anesthj-33	75	53	infusion	infusion	NOUN
anesthj-33	75	54	syndrome	syndrome	NOUN
anesthj-33	75	55	owing	owe	VERB
anesthj-33	75	56	to	to	ADP
anesthj-33	75	57	its	its	PRON
anesthj-33	75	58	inhibition	inhibition	NOUN
anesthj-33	75	59	of	of	ADP
anesthj-33	75	60	free	free	ADJ
anesthj-33	75	61	fatty	fatty	NOUN
anesthj-33	75	62	acids	acid	NOUN
anesthj-33	75	63	entering	enter	VERB
anesthj-33	75	64	the	the	DET
anesthj-33	75	65	mitochondria	mitochondria	NOUN
anesthj-33	75	66	,	,	PUNCT
anesthj-33	75	67	impairing	impair	VERB
anesthj-33	75	68	the	the	DET
anesthj-33	75	69	electron	electron	NOUN
anesthj-33	75	70	transport	transport	NOUN
anesthj-33	75	71	chain	chain	NOUN
anesthj-33	75	72	,	,	PUNCT
anesthj-33	75	73	and	and	CCONJ
anesthj-33	75	74	inhibiting	inhibit	VERB
anesthj-33	75	75	complex	complex	ADJ
anesthj-33	75	76	ii	ii	NOUN
anesthj-33	75	77	of	of	ADP
anesthj-33	75	78	the	the	DET
anesthj-33	75	79	respiratory	respiratory	ADJ
anesthj-33	75	80	chain	chain	NOUN
anesthj-33	75	81	.	.	PUNCT
anesthj-33	76	1	propofol	propofol	NOUN
anesthj-33	76	2	has	have	AUX
anesthj-33	76	3	been	be	AUX
anesthj-33	76	4	used	use	VERB
anesthj-33	76	5	in	in	ADP
anesthj-33	76	6	melas	mela	NOUN
anesthj-33	76	7	patients	patient	NOUN
anesthj-33	76	8	without	without	ADP
anesthj-33	76	9	any	any	DET
anesthj-33	76	10	adverse	adverse	ADJ
anesthj-33	76	11	side	side	NOUN
anesthj-33	76	12	effects	effect	NOUN
anesthj-33	76	13	,	,	PUNCT
anesthj-33	76	14	but	but	CCONJ
anesthj-33	76	15	prolonged	prolonged	ADJ
anesthj-33	76	16	infusions	infusion	NOUN
anesthj-33	76	17	can	can	AUX
anesthj-33	76	18	mimic	mimic	VERB
anesthj-33	76	19	mm	mm	NOUN
anesthj-33	76	20	symptoms	symptom	NOUN
anesthj-33	76	21	such	such	ADJ
anesthj-33	76	22	as	as	ADP
anesthj-33	76	23	lactic	lactic	ADJ
anesthj-33	76	24	acidosis.19,20	acidosis.19,20	ADJ
anesthj-33	76	25	use	use	NOUN
anesthj-33	76	26	of	of	ADP
anesthj-33	76	27	muscle	muscle	NOUN
anesthj-33	76	28	relaxants	relaxant	NOUN
anesthj-33	76	29	is	be	AUX
anesthj-33	76	30	also	also	ADV
anesthj-33	76	31	controversial	controversial	ADJ
anesthj-33	76	32	.	.	PUNCT
anesthj-33	77	1	melas	mela	NOUN
anesthj-33	77	2	has	have	AUX
anesthj-33	77	3	been	be	AUX
anesthj-33	77	4	shown	show	VERB
anesthj-33	77	5	to	to	PART
anesthj-33	77	6	cause	cause	VERB
anesthj-33	77	7	focal	focal	ADJ
anesthj-33	77	8	segmental	segmental	ADJ
anesthj-33	77	9	glomerulosclerosis	glomerulosclerosis	NOUN
anesthj-33	77	10	;	;	PUNCT
anesthj-33	77	11	thus	thus	ADV
anesthj-33	77	12	,	,	PUNCT
anesthj-33	77	13	it	it	PRON
anesthj-33	77	14	is	be	AUX
anesthj-33	77	15	imperative	imperative	ADJ
anesthj-33	77	16	to	to	PART
anesthj-33	77	17	take	take	VERB
anesthj-33	77	18	into	into	ADP
anesthj-33	77	19	consideration	consideration	NOUN
anesthj-33	77	20	not	not	PART
anesthj-33	77	21	administering	administer	VERB
anesthj-33	77	22	any	any	DET
anesthj-33	77	23	nephrotoxic	nephrotoxic	ADJ
anesthj-33	77	24	agents.21	agents.21	NOUN
anesthj-33	77	25	the	the	DET
anesthj-33	77	26	anesthetic	anesthetic	ADJ
anesthj-33	77	27	plan	plan	NOUN
anesthj-33	77	28	for	for	ADP
anesthj-33	77	29	the	the	DET
anesthj-33	77	30	patient	patient	NOUN
anesthj-33	77	31	in	in	ADP
anesthj-33	77	32	the	the	DET
anesthj-33	77	33	present	present	ADJ
anesthj-33	77	34	case	case	NOUN
anesthj-33	77	35	consisted	consist	VERB
anesthj-33	77	36	of	of	ADP
anesthj-33	77	37	using	use	VERB
anesthj-33	77	38	cisatracurium	cisatracurium	NOUN
anesthj-33	77	39	owing	owe	VERB
anesthj-33	77	40	to	to	ADP
anesthj-33	77	41	its	its	PRON
anesthj-33	77	42	elimination	elimination	NOUN
anesthj-33	77	43	via	via	ADP
anesthj-33	77	44	hoffman	hoffman	NOUN
anesthj-33	77	45	elimination	elimination	NOUN
anesthj-33	77	46	and	and	CCONJ
anesthj-33	77	47	ester	ester	NOUN
anesthj-33	77	48	hydrolysis	hydrolysis	NOUN
anesthj-33	77	49	.	.	PUNCT
anesthj-33	78	1	there	there	PRON
anesthj-33	78	2	has	have	AUX
anesthj-33	78	3	been	be	AUX
anesthj-33	78	4	one	one	NUM
anesthj-33	78	5	report	report	NOUN
anesthj-33	78	6	of	of	ADP
anesthj-33	78	7	resistance	resistance	NOUN
anesthj-33	78	8	to	to	PART
anesthj-33	78	9	cisatracurium	cisatracurium	VERB
anesthj-33	78	10	in	in	ADP
anesthj-33	78	11	a	a	DET
anesthj-33	78	12	melas	mela	NOUN
anesthj-33	78	13	patient	patient	NOUN
anesthj-33	78	14	,	,	PUNCT
anesthj-33	78	15	but	but	CCONJ
anesthj-33	78	16	this	this	DET
anesthj-33	78	17	patient	patient	NOUN
anesthj-33	78	18	received	receive	VERB
anesthj-33	78	19	a	a	DET
anesthj-33	78	20	full	full	ADJ
anesthj-33	78	21	intubating	intubate	VERB
anesthj-33	78	22	dose	dose	NOUN
anesthj-33	78	23	of	of	ADP
anesthj-33	78	24	cisatracurium	cisatracurium	PROPN
anesthj-33	78	25	with	with	ADP
anesthj-33	78	26	full	full	ADJ
anesthj-33	78	27	recovery	recovery	NOUN
anesthj-33	78	28	of	of	ADP
anesthj-33	78	29	train	train	NOUN
anesthj-33	78	30	-	-	PUNCT
anesthj-33	78	31	of	of	ADP
anesthj-33	78	32	-	-	PUNCT
anesthj-33	78	33	four	four	NUM
anesthj-33	78	34	and	and	CCONJ
anesthj-33	78	35	spontaneous	spontaneous	ADJ
anesthj-33	78	36	ventilation.22	ventilation.22	NOUN
anesthj-33	78	37	the	the	DET
anesthj-33	78	38	effects	effect	NOUN
anesthj-33	78	39	of	of	ADP
anesthj-33	78	40	volatile	volatile	ADJ
anesthj-33	78	41	anesthetics	anesthetic	NOUN
anesthj-33	78	42	on	on	ADP
anesthj-33	78	43	the	the	DET
anesthj-33	78	44	mitochondria	mitochondria	NOUN
anesthj-33	78	45	are	be	AUX
anesthj-33	78	46	debated	debate	VERB
anesthj-33	78	47	.	.	PUNCT
anesthj-33	79	1	they	they	PRON
anesthj-33	79	2	may	may	AUX
anesthj-33	79	3	have	have	VERB
anesthj-33	79	4	a	a	DET
anesthj-33	79	5	protective	protective	ADJ
anesthj-33	79	6	effect	effect	NOUN
anesthj-33	79	7	on	on	ADP
anesthj-33	79	8	the	the	DET
anesthj-33	79	9	mitochondria	mitochondria	NOUN
anesthj-33	79	10	owing	owe	VERB
anesthj-33	79	11	to	to	ADP
anesthj-33	79	12	ischemic	ischemic	ADJ
anesthj-33	79	13	preconditioning	precondition	VERB
anesthj-33	79	14	or	or	CCONJ
anesthj-33	79	15	they	they	PRON
anesthj-33	79	16	may	may	AUX
anesthj-33	79	17	inhibit	inhibit	VERB
anesthj-33	79	18	nadh	nadh	NOUN
anesthj-33	79	19	oxidation.20	oxidation.20	NOUN
anesthj-33	79	20	multiple	multiple	ADJ
anesthj-33	79	21	case	case	NOUN
anesthj-33	79	22	reports	report	NOUN
anesthj-33	79	23	have	have	AUX
anesthj-33	79	24	also	also	ADV
anesthj-33	79	25	documented	document	VERB
anesthj-33	79	26	the	the	DET
anesthj-33	79	27	successful	successful	ADJ
anesthj-33	79	28	administration	administration	NOUN
anesthj-33	79	29	of	of	ADP
anesthj-33	79	30	regional	regional	ADJ
anesthj-33	79	31	anesthetics	anesthetic	NOUN
anesthj-33	79	32	in	in	ADP
anesthj-33	79	33	melas	mela	NOUN
anesthj-33	79	34	patients	patient	NOUN
anesthj-33	79	35	without	without	ADP
anesthj-33	79	36	adverse	adverse	ADJ
anesthj-33	79	37	effects	effect	NOUN
anesthj-33	79	38	,	,	PUNCT
anesthj-33	79	39	including	include	VERB
anesthj-33	79	40	spinal	spinal	NOUN
anesthj-33	79	41	anesthesia	anesthesia	NOUN
anesthj-33	79	42	for	for	ADP
anesthj-33	79	43	a	a	DET
anesthj-33	79	44	femur	femur	ADJ
anesthj-33	79	45	fracture	fracture	NOUN
anesthj-33	79	46	,	,	PUNCT
anesthj-33	79	47	combined	combine	VERB
anesthj-33	79	48	general	general	ADJ
anesthj-33	79	49	endotracheal	endotracheal	NOUN
anesthj-33	79	50	anesthesia	anesthesia	NOUN
anesthj-33	79	51	with	with	ADP
anesthj-33	79	52	epidural	epidural	ADJ
anesthj-33	79	53	anesthesia	anesthesia	NOUN
anesthj-33	79	54	for	for	ADP
anesthj-33	79	55	gastrectomy	gastrectomy	NOUN
anesthj-33	79	56	,	,	PUNCT
anesthj-33	79	57	spinal	spinal	ADJ
anesthj-33	79	58	anesthesia	anesthesia	NOUN
anesthj-33	79	59	for	for	ADP
anesthj-33	79	60	appendectomy	appendectomy	NOUN
anesthj-33	79	61	,	,	PUNCT
anesthj-33	79	62	epidural	epidural	ADJ
anesthj-33	79	63	anesthesia	anesthesia	NOUN
anesthj-33	79	64	for	for	ADP
anesthj-33	79	65	postoperative	postoperative	ADJ
anesthj-33	79	66	pain	pain	NOUN
anesthj-33	79	67	control	control	NOUN
anesthj-33	79	68	after	after	ADP
anesthj-33	79	69	laparotomy	laparotomy	NOUN
anesthj-33	79	70	,	,	PUNCT
anesthj-33	79	71	combined	combine	VERB
anesthj-33	79	72	general	general	ADJ
anesthj-33	79	73	endotracheal	endotracheal	NOUN
anesthj-33	79	74	anesthesia	anesthesia	NOUN
anesthj-33	79	75	and	and	CCONJ
anesthj-33	79	76	postoperative	postoperative	ADJ
anesthj-33	79	77	epidural	epidural	ADJ
anesthj-33	79	78	anesthesia	anesthesia	NOUN
anesthj-33	79	79	for	for	ADP
anesthj-33	79	80	colectomy	colectomy	NOUN
anesthj-33	79	81	and	and	CCONJ
anesthj-33	79	82	ovariectomy	ovariectomy	NOUN
anesthj-33	79	83	,	,	PUNCT
anesthj-33	79	84	and	and	CCONJ
anesthj-33	79	85	epidural	epidural	ADJ
anesthj-33	79	86	catheter	catheter	NOUN
anesthj-33	79	87	placement	placement	NOUN
anesthj-33	79	88	for	for	ADP
anesthj-33	79	89	labor	labor	NOUN
anesthj-33	79	90	analgesia.12,19,23	analgesia.12,19,23	X
anesthj-33	79	91	-	-	SYM
anesthj-33	79	92	26	26	NUM
anesthj-33	79	93	it	it	PRON
anesthj-33	79	94	is	be	AUX
anesthj-33	79	95	still	still	ADV
anesthj-33	79	96	important	important	ADJ
anesthj-33	79	97	for	for	SCONJ
anesthj-33	79	98	the	the	DET
anesthj-33	79	99	anesthesia	anesthesia	PROPN
anesthj-33	79	100	professional	professional	NOUN
anesthj-33	79	101	to	to	PART
anesthj-33	79	102	consider	consider	VERB
anesthj-33	79	103	any	any	DET
anesthj-33	79	104	neurologic	neurologic	ADJ
anesthj-33	79	105	abnormalities	abnormality	NOUN
anesthj-33	79	106	of	of	ADP
anesthj-33	79	107	the	the	DET
anesthj-33	79	108	spinal	spinal	ADJ
anesthj-33	79	109	cord	cord	NOUN
anesthj-33	79	110	or	or	CCONJ
anesthj-33	79	111	peripheral	peripheral	ADJ
anesthj-33	79	112	nerves	nerve	NOUN
anesthj-33	79	113	and	and	CCONJ
anesthj-33	79	114	to	to	PART
anesthj-33	79	115	carefully	carefully	ADV
anesthj-33	79	116	consider	consider	VERB
anesthj-33	79	117	coagulation	coagulation	NOUN
anesthj-33	79	118	status	status	NOUN
anesthj-33	79	119	in	in	ADP
anesthj-33	79	120	this	this	DET
anesthj-33	79	121	patient	patient	ADJ
anesthj-33	79	122	population	population	NOUN
anesthj-33	79	123	.	.	PUNCT
anesthj-33	80	1	the	the	DET
anesthj-33	80	2	patient	patient	NOUN
anesthj-33	80	3	in	in	ADP
anesthj-33	80	4	this	this	DET
anesthj-33	80	5	case	case	NOUN
anesthj-33	80	6	had	have	VERB
anesthj-33	80	7	an	an	DET
anesthj-33	80	8	unsteady	unsteady	ADJ
anesthj-33	80	9	gait	gait	NOUN
anesthj-33	80	10	and	and	CCONJ
anesthj-33	80	11	normal	normal	ADJ
anesthj-33	80	12	coagulation	coagulation	NOUN
anesthj-33	80	13	studies	study	NOUN
anesthj-33	80	14	,	,	PUNCT
anesthj-33	80	15	but	but	CCONJ
anesthj-33	80	16	because	because	SCONJ
anesthj-33	80	17	of	of	ADP
anesthj-33	80	18	his	his	PRON
anesthj-33	80	19	muscle	muscle	NOUN
anesthj-33	80	20	wasting	waste	VERB
anesthj-33	80	21	,	,	PUNCT
anesthj-33	80	22	respiratory	respiratory	ADJ
anesthj-33	80	23	compromise	compromise	NOUN
anesthj-33	80	24	may	may	AUX
anesthj-33	80	25	have	have	AUX
anesthj-33	80	26	been	be	AUX
anesthj-33	80	27	a	a	DET
anesthj-33	80	28	possibility	possibility	NOUN
anesthj-33	80	29	if	if	SCONJ
anesthj-33	80	30	a	a	DET
anesthj-33	80	31	regional	regional	ADJ
anesthj-33	80	32	anesthetic	anesthetic	NOUN
anesthj-33	80	33	were	be	AUX
anesthj-33	80	34	chosen	choose	VERB
anesthj-33	80	35	and	and	CCONJ
anesthj-33	80	36	if	if	SCONJ
anesthj-33	80	37	the	the	DET
anesthj-33	80	38	level	level	NOUN
anesthj-33	80	39	of	of	ADP
anesthj-33	80	40	block	block	NOUN
anesthj-33	80	41	was	be	AUX
anesthj-33	80	42	too	too	ADV
anesthj-33	80	43	high	high	ADJ
anesthj-33	80	44	.	.	PUNCT
anesthj-33	81	1	even	even	ADV
anesthj-33	81	2	though	though	SCONJ
anesthj-33	81	3	the	the	DET
anesthj-33	81	4	obvious	obvious	ADJ
anesthj-33	81	5	safety	safety	NOUN
anesthj-33	81	6	of	of	ADP
anesthj-33	81	7	regional	regional	ADJ
anesthj-33	81	8	anesthesia	anesthesia	PROPN
anesthj-33	81	9	has	have	AUX
anesthj-33	81	10	been	be	AUX
anesthj-33	81	11	confirmed	confirm	VERB
anesthj-33	81	12	,	,	PUNCT
anesthj-33	81	13	local	local	ADJ
anesthj-33	81	14	anesthetics	anesthetic	NOUN
anesthj-33	81	15	still	still	ADV
anesthj-33	81	16	affect	affect	VERB
anesthj-33	81	17	the	the	DET
anesthj-33	81	18	mitochondrion	mitochondrion	NOUN
anesthj-33	81	19	.	.	PUNCT
anesthj-33	82	1	this	this	PRON
anesthj-33	82	2	presents	present	VERB
anesthj-33	82	3	another	another	DET
anesthj-33	82	4	problem	problem	NOUN
anesthj-33	82	5	that	that	SCONJ
anesthj-33	82	6	the	the	DET
anesthj-33	82	7	literature	literature	NOUN
anesthj-33	82	8	can	can	AUX
anesthj-33	82	9	not	not	PART
anesthj-33	82	10	answer	answer	VERB
anesthj-33	82	11	regarding	regard	VERB
anesthj-33	82	12	melas	mela	NOUN
anesthj-33	82	13	patients	patient	NOUN
anesthj-33	82	14	.	.	PUNCT
anesthj-33	83	1	local	local	ADJ
anesthj-33	83	2	anesthetics	anesthetic	NOUN
anesthj-33	83	3	such	such	ADJ
anesthj-33	83	4	as	as	ADP
anesthj-33	83	5	bupivacaine	bupivacaine	NOUN
anesthj-33	83	6	have	have	AUX
anesthj-33	83	7	been	be	AUX
anesthj-33	83	8	shown	show	VERB
anesthj-33	83	9	to	to	PART
anesthj-33	83	10	inhibit	inhibit	VERB
anesthj-33	83	11	the	the	DET
anesthj-33	83	12	mitochondrial	mitochondrial	ADJ
anesthj-33	83	13	respiratory	respiratory	ADJ
anesthj-33	83	14	chain	chain	NOUN
anesthj-33	83	15	complex	complex	NOUN
anesthj-33	83	16	i	i	PRON
anesthj-33	83	17	and	and	CCONJ
anesthj-33	83	18	cause	cause	VERB
anesthj-33	83	19	oxidative	oxidative	ADJ
anesthj-33	83	20	phosphorylation	phosphorylation	NOUN
anesthj-33	83	21	uncoupling	uncouple	VERB
anesthj-33	83	22	that	that	PRON
anesthj-33	83	23	is	be	AUX
anesthj-33	83	24	potentially	potentially	ADV
anesthj-33	83	25	detrimental	detrimental	ADJ
anesthj-33	83	26	to	to	ADP
anesthj-33	83	27	melas	melas	PROPN
anesthj-33	83	28	patients.27	patients.27	PROPN
anesthj-33	83	29	upon	upon	SCONJ
anesthj-33	83	30	induction	induction	NOUN
anesthj-33	83	31	,	,	PUNCT
anesthj-33	83	32	modified	modify	VERB
anesthj-33	83	33	rapid	rapid	ADJ
anesthj-33	83	34	sequence	sequence	NOUN
anesthj-33	83	35	induction	induction	NOUN
anesthj-33	83	36	with	with	ADP
anesthj-33	83	37	cricoid	cricoid	ADJ
anesthj-33	83	38	pressure	pressure	NOUN
anesthj-33	83	39	should	should	AUX
anesthj-33	83	40	be	be	AUX
anesthj-33	83	41	instituted	institute	VERB
anesthj-33	83	42	in	in	ADP
anesthj-33	83	43	patients	patient	NOUN
anesthj-33	83	44	with	with	ADP
anesthj-33	83	45	gastric	gastric	ADJ
anesthj-33	83	46	involvement	involvement	NOUN
anesthj-33	83	47	such	such	ADJ
anesthj-33	83	48	as	as	ADP
anesthj-33	83	49	nausea	nausea	NOUN
anesthj-33	83	50	and	and	CCONJ
anesthj-33	83	51	vomiting.11	vomiting.11	VERB
anesthj-33	83	52	use	use	NOUN
anesthj-33	83	53	of	of	ADP
anesthj-33	83	54	histamine-2	histamine-2	NUM
anesthj-33	83	55	receptor	receptor	NOUN
anesthj-33	83	56	antagonists	antagonist	NOUN
anesthj-33	83	57	and	and	CCONJ
anesthj-33	83	58	proton	proton	NOUN
anesthj-33	83	59	pump	pump	NOUN
anesthj-33	83	60	inhibitors	inhibitor	NOUN
anesthj-33	83	61	may	may	AUX
anesthj-33	83	62	also	also	ADV
anesthj-33	83	63	be	be	AUX
anesthj-33	83	64	helpful	helpful	ADJ
anesthj-33	83	65	to	to	PART
anesthj-33	83	66	reduce	reduce	VERB
anesthj-33	83	67	aspiration	aspiration	NOUN
anesthj-33	83	68	risk.11	risk.11	VERB
anesthj-33	83	69	the	the	DET
anesthj-33	83	70	patient	patient	NOUN
anesthj-33	83	71	in	in	ADP
anesthj-33	83	72	this	this	DET
anesthj-33	83	73	case	case	NOUN
anesthj-33	83	74	did	do	AUX
anesthj-33	83	75	not	not	PART
anesthj-33	83	76	have	have	VERB
anesthj-33	83	77	any	any	DET
anesthj-33	83	78	gastrointestinal	gastrointestinal	ADJ
anesthj-33	83	79	dysfunction	dysfunction	NOUN
anesthj-33	83	80	and	and	CCONJ
anesthj-33	83	81	thus	thus	ADV
anesthj-33	83	82	this	this	PRON
anesthj-33	83	83	was	be	AUX
anesthj-33	83	84	not	not	PART
anesthj-33	83	85	performed	perform	VERB
anesthj-33	83	86	.	.	PUNCT
anesthj-33	84	1	a	a	DET
anesthj-33	84	2	cardiovascularly	cardiovascularly	PROPN
anesthj-33	84	3	stable	stable	ADJ
anesthj-33	84	4	anesthetic	anesthetic	NOUN
anesthj-33	84	5	is	be	AUX
anesthj-33	84	6	best	good	ADJ
anesthj-33	84	7	for	for	ADP
anesthj-33	84	8	melas	mela	NOUN
anesthj-33	84	9	patients	patient	NOUN
anesthj-33	84	10	because	because	SCONJ
anesthj-33	84	11	aerobic	aerobic	ADJ
anesthj-33	84	12	metabolism	metabolism	NOUN
anesthj-33	84	13	is	be	AUX
anesthj-33	84	14	already	already	ADV
anesthj-33	84	15	dysfunctional	dysfunctional	ADJ
anesthj-33	84	16	in	in	ADP
anesthj-33	84	17	this	this	DET
anesthj-33	84	18	patient	patient	NOUN
anesthj-33	84	19	group.11	group.11	VERB
anesthj-33	84	20	intraoperative	intraoperative	ADJ
anesthj-33	84	21	considerations	consideration	NOUN
anesthj-33	84	22	include	include	VERB
anesthj-33	84	23	maintaining	maintain	VERB
anesthj-33	84	24	normothermia	normothermia	NOUN
anesthj-33	84	25	in	in	ADP
anesthj-33	84	26	the	the	DET
anesthj-33	84	27	melas	mela	NOUN
anesthj-33	84	28	patient	patient	NOUN
anesthj-33	84	29	owing	owe	VERB
anesthj-33	84	30	to	to	ADP
anesthj-33	84	31	the	the	DET
anesthj-33	84	32	impaired	impaired	ADJ
anesthj-33	84	33	mitochondrial	mitochondrial	ADJ
anesthj-33	84	34	chain	chain	NOUN
anesthj-33	84	35	,	,	PUNCT
anesthj-33	84	36	which	which	PRON
anesthj-33	84	37	is	be	AUX
anesthj-33	84	38	responsible	responsible	ADJ
anesthj-33	84	39	for	for	ADP
anesthj-33	84	40	heat	heat	NOUN
anesthj-33	84	41	maintenance	maintenance	NOUN
anesthj-33	84	42	.	.	PUNCT
anesthj-33	85	1	this	this	PRON
anesthj-33	85	2	includes	include	VERB
anesthj-33	85	3	monitoring	monitor	VERB
anesthj-33	85	4	temperature	temperature	NOUN
anesthj-33	85	5	through	through	ADP
anesthj-33	85	6	a	a	DET
anesthj-33	85	7	nasopharyngeal	nasopharyngeal	ADJ
anesthj-33	85	8	probe	probe	NOUN
anesthj-33	85	9	and	and	CCONJ
anesthj-33	85	10	warming	warm	VERB
anesthj-33	85	11	intravenous	intravenous	ADJ
anesthj-33	85	12	fluids	fluid	NOUN
anesthj-33	85	13	and	and	CCONJ
anesthj-33	85	14	using	use	VERB
anesthj-33	85	15	a	a	DET
anesthj-33	85	16	forced	force	VERB
anesthj-33	85	17	air	air	NOUN
anesthj-33	85	18	warmer.11	warmer.11	NOUN
anesthj-33	85	19	these	these	DET
anesthj-33	85	20	interventions	intervention	NOUN
anesthj-33	85	21	were	be	AUX
anesthj-33	85	22	used	use	VERB
anesthj-33	85	23	in	in	ADP
anesthj-33	85	24	the	the	DET
anesthj-33	85	25	anesthetic	anesthetic	ADJ
anesthj-33	85	26	plan	plan	NOUN
anesthj-33	85	27	for	for	ADP
anesthj-33	85	28	this	this	DET
anesthj-33	85	29	melas	mela	NOUN
anesthj-33	85	30	patient	patient	NOUN
anesthj-33	85	31	.	.	PUNCT
anesthj-33	86	1	arterial	arterial	ADJ
anesthj-33	86	2	blood	blood	NOUN
anesthj-33	86	3	gas	gas	NOUN
anesthj-33	86	4	analysis	analysis	NOUN
anesthj-33	86	5	intraoperatively	intraoperatively	ADV
anesthj-33	86	6	may	may	AUX
anesthj-33	86	7	be	be	AUX
anesthj-33	86	8	appropriate	appropriate	ADJ
anesthj-33	86	9	to	to	PART
anesthj-33	86	10	check	check	VERB
anesthj-33	86	11	glucose	glucose	NOUN
anesthj-33	86	12	and	and	CCONJ
anesthj-33	86	13	lactate	lactate	NOUN
anesthj-33	86	14	levels	level	NOUN
anesthj-33	86	15	.	.	PUNCT
anesthj-33	87	1	careful	careful	ADJ
anesthj-33	87	2	titration	titration	NOUN
anesthj-33	87	3	of	of	ADP
anesthj-33	87	4	muscle	muscle	NOUN
anesthj-33	87	5	relaxants	relaxant	NOUN
anesthj-33	87	6	and	and	CCONJ
anesthj-33	87	7	opiates	opiate	NOUN
anesthj-33	87	8	must	must	AUX
anesthj-33	87	9	be	be	AUX
anesthj-33	87	10	evaluated	evaluate	VERB
anesthj-33	87	11	by	by	ADP
anesthj-33	87	12	using	use	VERB
anesthj-33	87	13	a	a	DET
anesthj-33	87	14	peripheral	peripheral	ADJ
anesthj-33	87	15	nerve	nerve	NOUN
anesthj-33	87	16	stimulator	stimulator	NOUN
anesthj-33	87	17	and	and	CCONJ
anesthj-33	87	18	spontaneous	spontaneous	ADJ
anesthj-33	87	19	ventilation	ventilation	NOUN
anesthj-33	87	20	.	.	PUNCT
anesthj-33	88	1	adequate	adequate	ADJ
anesthj-33	88	2	hydration	hydration	NOUN
anesthj-33	88	3	is	be	AUX
anesthj-33	88	4	paramount	paramount	ADJ
anesthj-33	88	5	.	.	PUNCT
anesthj-33	89	1	postoperative	postoperative	ADJ
anesthj-33	89	2	considerations	consideration	NOUN
anesthj-33	89	3	must	must	AUX
anesthj-33	89	4	include	include	VERB
anesthj-33	89	5	possible	possible	ADJ
anesthj-33	89	6	metabolic	metabolic	NOUN
anesthj-33	89	7	disturbances	disturbance	NOUN
anesthj-33	89	8	,	,	PUNCT
anesthj-33	89	9	postoperative	postoperative	ADJ
anesthj-33	89	10	respiratory	respiratory	ADJ
anesthj-33	89	11	failure	failure	NOUN
anesthj-33	89	12	,	,	PUNCT
anesthj-33	89	13	and	and	CCONJ
anesthj-33	89	14	adequate	adequate	ADJ
anesthj-33	89	15	analgesia	analgesia	NOUN
anesthj-33	89	16	to	to	PART
anesthj-33	89	17	prevent	prevent	VERB
anesthj-33	89	18	acidosis	acidosis	NOUN
anesthj-33	89	19	.	.	PUNCT
anesthj-33	90	1	other	other	ADJ
anesthj-33	90	2	considerations	consideration	NOUN
anesthj-33	90	3	can	can	AUX
anesthj-33	90	4	include	include	VERB
anesthj-33	90	5	adequate	adequate	ADJ
anesthj-33	90	6	control	control	NOUN
anesthj-33	90	7	of	of	ADP
anesthj-33	90	8	nausea	nausea	NOUN
anesthj-33	90	9	and	and	CCONJ
anesthj-33	90	10	vomiting	vomiting	NOUN
anesthj-33	90	11	and	and	CCONJ
anesthj-33	90	12	postoperative	postoperative	ADJ
anesthj-33	90	13	shivering	shivering	NOUN
anesthj-33	90	14	.	.	PUNCT
anesthj-33	91	1	these	these	DET
anesthj-33	91	2	patients	patient	NOUN
anesthj-33	91	3	should	should	AUX
anesthj-33	91	4	be	be	AUX
anesthj-33	91	5	monitored	monitor	VERB
anesthj-33	91	6	in	in	ADP
anesthj-33	91	7	the	the	DET
anesthj-33	91	8	intensive	intensive	ADJ
anesthj-33	91	9	care	care	NOUN
anesthj-33	91	10	unit	unit	NOUN
anesthj-33	91	11	because	because	SCONJ
anesthj-33	91	12	of	of	ADP
anesthj-33	91	13	the	the	DET
anesthj-33	91	14	potential	potential	NOUN
anesthj-33	91	15	for	for	ADP
anesthj-33	91	16	metabolic	metabolic	NOUN
anesthj-33	91	17	disturbances	disturbance	NOUN
anesthj-33	91	18	.	.	PUNCT
anesthj-33	92	1	ideally	ideally	ADV
anesthj-33	92	2	,	,	PUNCT
anesthj-33	92	3	clinical	clinical	ADJ
anesthj-33	92	4	trials	trial	NOUN
anesthj-33	92	5	need	need	VERB
anesthj-33	92	6	to	to	PART
anesthj-33	92	7	be	be	AUX
anesthj-33	92	8	performed	perform	VERB
anesthj-33	92	9	specifically	specifically	ADV
anesthj-33	92	10	for	for	ADP
anesthj-33	92	11	melas	mela	NOUN
anesthj-33	92	12	patients	patient	NOUN
anesthj-33	92	13	with	with	ADP
anesthj-33	92	14	the	the	DET
anesthj-33	92	15	same	same	ADJ
anesthj-33	92	16	genetic	genetic	ADJ
anesthj-33	92	17	defect	defect	NOUN
anesthj-33	92	18	and	and	CCONJ
anesthj-33	92	19	same	same	ADJ
anesthj-33	92	20	presentation	presentation	NOUN
anesthj-33	92	21	,	,	PUNCT
anesthj-33	92	22	which	which	PRON
anesthj-33	92	23	would	would	AUX
anesthj-33	92	24	require	require	VERB
anesthj-33	92	25	international	international	ADJ
anesthj-33	92	26	collaboration	collaboration	NOUN
anesthj-33	92	27	to	to	PART
anesthj-33	92	28	obtain	obtain	VERB
anesthj-33	92	29	an	an	DET
anesthj-33	92	30	adequate	adequate	ADJ
anesthj-33	92	31	sample	sample	NOUN
anesthj-33	92	32	size.28	size.28	NOUN
anesthj-33	92	33	these	these	DET
anesthj-33	92	34	trials	trial	NOUN
anesthj-33	92	35	would	would	AUX
anesthj-33	92	36	need	need	VERB
anesthj-33	92	37	to	to	PART
anesthj-33	92	38	investigate	investigate	VERB
anesthj-33	92	39	the	the	DET
anesthj-33	92	40	pharmacology	pharmacology	NOUN
anesthj-33	92	41	of	of	ADP
anesthj-33	92	42	anesthetic	anesthetic	ADJ
anesthj-33	92	43	agents	agent	NOUN
anesthj-33	92	44	as	as	SCONJ
anesthj-33	92	45	it	it	PRON
anesthj-33	92	46	relates	relate	VERB
anesthj-33	92	47	to	to	ADP
anesthj-33	92	48	melas	melas	PROPN
anesthj-33	92	49	and	and	CCONJ
anesthj-33	92	50	other	other	ADJ
anesthj-33	92	51	mitochondrial	mitochondrial	ADJ
anesthj-33	92	52	disorders	disorder	NOUN
anesthj-33	92	53	at	at	ADP
anesthj-33	92	54	a	a	DET
anesthj-33	92	55	similar	similar	ADJ
anesthj-33	92	56	stage	stage	NOUN
anesthj-33	92	57	of	of	ADP
anesthj-33	92	58	disease	disease	NOUN
anesthj-33	92	59	progression	progression	NOUN
anesthj-33	92	60	and	and	CCONJ
anesthj-33	92	61	similar	similar	ADJ
anesthj-33	92	62	mitochondrial	mitochondrial	ADJ
anesthj-33	92	63	dna	dna	NOUN
anesthj-33	92	64	mutations	mutation	NOUN
anesthj-33	92	65	with	with	ADP
anesthj-33	92	66	adequate	adequate	ADJ
anesthj-33	92	67	power	power	NOUN
anesthj-33	92	68	,	,	PUNCT
anesthj-33	92	69	statistically	statistically	ADV
anesthj-33	92	70	validity	validity	NOUN
anesthj-33	92	71	,	,	PUNCT
anesthj-33	92	72	and	and	CCONJ
anesthj-33	92	73	double	double	ADJ
anesthj-33	92	74	-	-	PUNCT
anesthj-33	92	75	blinded	blind	VERB
anesthj-33	92	76	randomization.28	randomization.28	NOUN
anesthj-33	92	77	anesthesia	anesthesia	PROPN
anesthj-33	92	78	professionals	professional	NOUN
anesthj-33	92	79	could	could	AUX
anesthj-33	92	80	look	look	VERB
anesthj-33	92	81	to	to	ADP
anesthj-33	92	82	national	national	ADJ
anesthj-33	92	83	consortia	consortium	NOUN
anesthj-33	92	84	such	such	ADJ
anesthj-33	92	85	as	as	ADP
anesthj-33	92	86	the	the	DET
anesthj-33	92	87	north	north	ADJ
anesthj-33	92	88	american	american	ADJ
anesthj-33	92	89	mitochondrial	mitochondrial	ADJ
anesthj-33	92	90	disease	disease	NOUN
anesthj-33	92	91	consortium	consortium	NOUN
anesthj-33	92	92	to	to	PART
anesthj-33	92	93	recruit	recruit	VERB
anesthj-33	92	94	participants	participant	NOUN
anesthj-33	92	95	for	for	ADP
anesthj-33	92	96	future	future	ADJ
anesthj-33	92	97	clinical	clinical	ADJ
anesthj-33	92	98	trials.28	trials.28	NOUN
anesthj-33	92	99	as	as	SCONJ
anesthj-33	92	100	more	more	ADJ
anesthj-33	92	101	pathophysiologic	pathophysiologic	ADJ
anesthj-33	92	102	advances	advance	NOUN
anesthj-33	92	103	occur	occur	VERB
anesthj-33	92	104	in	in	ADP
anesthj-33	92	105	the	the	DET
anesthj-33	92	106	understanding	understanding	NOUN
anesthj-33	92	107	of	of	ADP
anesthj-33	92	108	mms	mms	NOUN
anesthj-33	92	109	,	,	PUNCT
anesthj-33	92	110	anesthetic	anesthetic	ADJ
anesthj-33	92	111	management	management	NOUN
anesthj-33	92	112	will	will	AUX
anesthj-33	92	113	improve.28	improve.28	VERB
anesthj-33	92	114	meanwhile	meanwhile	ADV
anesthj-33	92	115	,	,	PUNCT
anesthj-33	92	116	each	each	DET
anesthj-33	92	117	melas	mela	NOUN
anesthj-33	92	118	patient	patient	NOUN
anesthj-33	92	119	and	and	CCONJ
anesthj-33	92	120	each	each	DET
anesthj-33	92	121	patient	patient	NOUN
anesthj-33	92	122	with	with	ADP
anesthj-33	92	123	mm	mm	PROPN
anesthj-33	92	124	should	should	AUX
anesthj-33	92	125	be	be	AUX
anesthj-33	92	126	treated	treat	VERB
anesthj-33	92	127	individually	individually	ADV
anesthj-33	92	128	and	and	CCONJ
anesthj-33	92	129	the	the	DET
anesthj-33	92	130	anesthetic	anesthetic	ADJ
anesthj-33	92	131	plan	plan	NOUN
anesthj-33	92	132	should	should	AUX
anesthj-33	92	133	be	be	AUX
anesthj-33	92	134	adjusted	adjust	VERB
anesthj-33	92	135	accordingly	accordingly	ADV
anesthj-33	92	136	.	.	PUNCT
anesthj-33	93	1	anesthesia	anesthesia	PROPN
anesthj-33	93	2	ejournal	ejournal	PROPN
anesthj-33	93	3	www.anesthesiaejournal.com	www.anesthesiaejournal.com	PROPN
anesthj-33	93	4	volume	volume	NOUN
anesthj-33	93	5	4	4	NUM
anesthj-33	93	6	issue	issue	NOUN
anesthj-33	93	7	1	1	NUM
anesthj-33	93	8	2016	2016	NUM
anesthj-33	93	9	page	page	NOUN
anesthj-33	93	10	24	24	NUM
anesthj-33	93	11	references	reference	NOUN
anesthj-33	93	12	1	1	NUM
anesthj-33	93	13	.	.	PUNCT
anesthj-33	93	14	rivera	rivera	PROPN
anesthj-33	93	15	-	-	PUNCT
anesthj-33	93	16	cruz	cruz	PROPN
anesthj-33	93	17	b.	b.	PROPN
anesthj-33	93	18	mitochondrial	mitochondrial	ADJ
anesthj-33	93	19	diseases	disease	NOUN
anesthj-33	93	20	and	and	CCONJ
anesthj-33	93	21	anesthesia	anesthesia	NOUN
anesthj-33	93	22	:	:	PUNCT
anesthj-33	93	23	a	a	DET
anesthj-33	93	24	literature	literature	NOUN
anesthj-33	93	25	review	review	NOUN
anesthj-33	93	26	of	of	ADP
anesthj-33	93	27	current	current	ADJ
anesthj-33	93	28	opinions	opinion	NOUN
anesthj-33	93	29	.	.	PUNCT
anesthj-33	94	1	aana	aana	PROPN
anesthj-33	94	2	j.	j.	PROPN
anesthj-33	94	3	2013;81(3):237	2013;81(3):237	PROPN
anesthj-33	94	4	-	-	SYM
anesthj-33	94	5	245	245	NUM
anesthj-33	94	6	.	.	NOUN
anesthj-33	95	1	2	2	X
anesthj-33	95	2	.	.	X
anesthj-33	95	3	gurrieri	gurrieri	PROPN
anesthj-33	95	4	c	c	PROPN
anesthj-33	95	5	,	,	PUNCT
anesthj-33	95	6	kivela	kivela	PROPN
anesthj-33	95	7	je	je	PROPN
anesthj-33	95	8	,	,	PUNCT
anesthj-33	95	9	bojanic	bojanic	PROPN
anesthj-33	95	10	k	k	PROPN
anesthj-33	95	11	,	,	PUNCT
anesthj-33	95	12	et	et	PROPN
anesthj-33	95	13	al	al	PROPN
anesthj-33	95	14	.	.	PUNCT
anesthj-33	96	1	anesthetic	anesthetic	ADJ
anesthj-33	96	2	considerations	consideration	NOUN
anesthj-33	96	3	in	in	ADP
anesthj-33	96	4	mitochondrial	mitochondrial	ADJ
anesthj-33	96	5	encephalomyopathy	encephalomyopathy	ADJ
anesthj-33	96	6	,	,	PUNCT
anesthj-33	96	7	lactic	lactic	ADJ
anesthj-33	96	8	acidosis	acidosis	NOUN
anesthj-33	96	9	,	,	PUNCT
anesthj-33	96	10	and	and	CCONJ
anesthj-33	96	11	stroke	stroke	NOUN
anesthj-33	96	12	-	-	PUNCT
anesthj-33	96	13	like	like	ADJ
anesthj-33	96	14	episodes	episode	NOUN
anesthj-33	96	15	syndrome	syndrome	NOUN
anesthj-33	96	16	:	:	PUNCT
anesthj-33	96	17	a	a	DET
anesthj-33	96	18	case	case	NOUN
anesthj-33	96	19	series	series	NOUN
anesthj-33	96	20	.	.	PUNCT
anesthj-33	97	1	can	can	AUX
anesthj-33	97	2	j	j	PROPN
anesthj-33	97	3	anesth	anesth	VERB
anesthj-33	97	4	.	.	PUNCT
anesthj-33	98	1	2011;58(8):751	2011;58(8):751	NUM
anesthj-33	98	2	-	-	PUNCT
anesthj-33	98	3	763	763	NUM
anesthj-33	98	4	.	.	PUNCT
anesthj-33	99	1	http://dx.doi.org/10.1007/s12630-011-9528-0	http://dx.doi.org/10.1007/s12630-011-9528-0	X
anesthj-33	99	2	.	.	PROPN
anesthj-33	100	1	3	3	NUM
anesthj-33	100	2	.	.	X
anesthj-33	100	3	wallace	wallace	PROPN
anesthj-33	100	4	dc	dc	PROPN
anesthj-33	100	5	.	.	PUNCT
anesthj-33	101	1	mitochondrial	mitochondrial	ADJ
anesthj-33	101	2	diseases	disease	NOUN
anesthj-33	101	3	in	in	ADP
anesthj-33	101	4	man	man	NOUN
anesthj-33	101	5	and	and	CCONJ
anesthj-33	101	6	mouse	mouse	NOUN
anesthj-33	101	7	.	.	PUNCT
anesthj-33	102	1	science	science	NOUN
anesthj-33	102	2	.	.	PUNCT
anesthj-33	103	1	1999;283(5407):1482	1999;283(5407):1482	NUM
anesthj-33	103	2	-	-	SYM
anesthj-33	103	3	1488	1488	NUM
anesthj-33	103	4	.	.	PUNCT
anesthj-33	104	1	http://dx.doi.org/10.1126/	http://dx.doi.org/10.1126/	PUNCT
anesthj-33	104	2	science.283.5407.1482	science.283.5407.1482	PROPN
anesthj-33	104	3	.	.	PROPN
anesthj-33	105	1	4	4	X
anesthj-33	105	2	.	.	X
anesthj-33	105	3	finsterer	finsterer	PROPN
anesthj-33	105	4	j.	j.	PROPN
anesthj-33	105	5	central	central	PROPN
anesthj-33	105	6	nervous	nervous	ADJ
anesthj-33	105	7	system	system	NOUN
anesthj-33	105	8	manifestations	manifestation	NOUN
anesthj-33	105	9	of	of	ADP
anesthj-33	105	10	mitochondrial	mitochondrial	ADJ
anesthj-33	105	11	disorders	disorder	NOUN
anesthj-33	105	12	.	.	PUNCT
anesthj-33	106	1	acta	acta	PROPN
anesthj-33	106	2	neurol	neurol	PROPN
anesthj-33	106	3	scand	scand	PROPN
anesthj-33	106	4	.	.	PUNCT
anesthj-33	107	1	2006;114(4):217	2006;114(4):217	X
anesthj-33	107	2	-	-	SYM
anesthj-33	107	3	238	238	NUM
anesthj-33	107	4	.	.	PUNCT
anesthj-33	108	1	http://	http://	PROPN
anesthj-33	108	2	dx.doi.org/10.1111/j.1600-0404.2006.00671.x	dx.doi.org/10.1111/j.1600-0404.2006.00671.x	NOUN
anesthj-33	108	3	.	.	PROPN
anesthj-33	109	1	5	5	NUM
anesthj-33	109	2	.	.	X
anesthj-33	109	3	niezgoda	niezgoda	PROPN
anesthj-33	109	4	j	j	PROPN
anesthj-33	109	5	,	,	PUNCT
anesthj-33	109	6	morgan	morgan	PROPN
anesthj-33	109	7	pg	pg	PROPN
anesthj-33	109	8	.	.	PUNCT
anesthj-33	110	1	anesthetic	anesthetic	ADJ
anesthj-33	110	2	considerations	consideration	NOUN
anesthj-33	110	3	in	in	ADP
anesthj-33	110	4	patients	patient	NOUN
anesthj-33	110	5	with	with	ADP
anesthj-33	110	6	mitochondrial	mitochondrial	ADJ
anesthj-33	110	7	defects	defect	NOUN
anesthj-33	110	8	.	.	PUNCT
anesthj-33	111	1	pediatr	pediatr	PROPN
anesthj-33	111	2	anesth	anesth	PROPN
anesthj-33	111	3	.	.	PUNCT
anesthj-33	112	1	2013;23(9):785	2013;23(9):785	NUM
anesthj-33	112	2	-	-	SYM
anesthj-33	112	3	793	793	NUM
anesthj-33	112	4	.	.	PUNCT
anesthj-33	113	1	http://dx.doi.org/10.1111/pan.12158	http://dx.doi.org/10.1111/pan.12158	NOUN
anesthj-33	113	2	.	.	PUNCT
anesthj-33	114	1	6	6	X
anesthj-33	114	2	.	.	X
anesthj-33	114	3	finsterer	finsterer	PROPN
anesthj-33	114	4	j.	j.	PROPN
anesthj-33	114	5	mitochondriopathies	mitochondriopathies	PROPN
anesthj-33	114	6	.	.	PUNCT
anesthj-33	115	1	eur	eur	PROPN
anesthj-33	115	2	j	j	PROPN
anesthj-33	115	3	neurol	neurol	NOUN
anesthj-33	115	4	.	.	PUNCT
anesthj-33	116	1	2004;11:163	2004;11:163	NUM
anesthj-33	116	2	-	-	SYM
anesthj-33	116	3	168	168	NUM
anesthj-33	116	4	.	.	PUNCT
anesthj-33	117	1	http://dx.doi.org/10.1046/j.1351-5101.2003.00728.x	http://dx.doi.org/10.1046/j.1351-5101.2003.00728.x	ADJ
anesthj-33	117	2	.	.	NOUN
anesthj-33	118	1	7	7	X
anesthj-33	118	2	.	.	X
anesthj-33	118	3	pfeffer	pfeffer	PROPN
anesthj-33	118	4	g	g	PROPN
anesthj-33	118	5	,	,	PUNCT
anesthj-33	118	6	chinnery	chinnery	PROPN
anesthj-33	118	7	pf	pf	PROPN
anesthj-33	118	8	.	.	PUNCT
anesthj-33	118	9	diagnosis	diagnosis	NOUN
anesthj-33	118	10	and	and	CCONJ
anesthj-33	118	11	treatment	treatment	NOUN
anesthj-33	118	12	of	of	ADP
anesthj-33	118	13	mitochondrial	mitochondrial	ADJ
anesthj-33	118	14	myopathies	myopathy	NOUN
anesthj-33	118	15	.	.	PUNCT
anesthj-33	119	1	ann	ann	PROPN
anesthj-33	119	2	med	med	PROPN
anesthj-33	119	3	.	.	PUNCT
anesthj-33	120	1	2013;45(1):4	2013;45(1):4	NUM
anesthj-33	120	2	-	-	SYM
anesthj-33	120	3	16	16	NUM
anesthj-33	120	4	.	.	PUNCT
anesthj-33	121	1	http://dx.doi.org/10	http://dx.doi.org/10	PROPN
anesthj-33	121	2	.3109/07853890.2011.605389	.3109/07853890.2011.605389	PROPN
anesthj-33	121	3	.	.	PUNCT
anesthj-33	122	1	8	8	NUM
anesthj-33	122	2	.	.	PUNCT
anesthj-33	122	3	codier	codier	NOUN
anesthj-33	122	4	e	e	NOUN
anesthj-33	122	5	,	,	PUNCT
anesthj-33	122	6	codier	codi	ADJ
anesthj-33	122	7	d.	d.	NOUN
anesthj-33	122	8	understanding	understand	VERB
anesthj-33	122	9	mitochondrial	mitochondrial	ADJ
anesthj-33	122	10	disease	disease	NOUN
anesthj-33	122	11	and	and	CCONJ
anesthj-33	122	12	goals	goal	NOUN
anesthj-33	122	13	for	for	ADP
anesthj-33	122	14	its	its	PRON
anesthj-33	122	15	treatment	treatment	NOUN
anesthj-33	122	16	.	.	PUNCT
anesthj-33	123	1	br	br	PROPN
anesthj-33	123	2	j	j	PROPN
anesthj-33	123	3	nurs	nur	VERB
anesthj-33	123	4	.	.	PUNCT
anesthj-33	124	1	2014;23(5):254	2014;23(5):254	NUM
anesthj-33	124	2	-	-	PUNCT
anesthj-33	124	3	260	260	NUM
anesthj-33	124	4	.	.	PUNCT
anesthj-33	125	1	http://	http://	PROPN
anesthj-33	125	2	dx.doi.org/10.12968/bjon.2014.23.5.254	dx.doi.org/10.12968/bjon.2014.23.5.254	PROPN
anesthj-33	125	3	.	.	PUNCT
anesthj-33	126	1	9	9	NUM
anesthj-33	126	2	.	.	X
anesthj-33	126	3	online	online	ADJ
anesthj-33	126	4	mendelian	mendelian	ADJ
anesthj-33	126	5	inheritance	inheritance	NOUN
anesthj-33	126	6	in	in	ADP
anesthj-33	126	7	man	man	NOUN
anesthj-33	126	8	.	.	PUNCT
anesthj-33	127	1	http://omim.org/entry/540000	http://omim.org/entry/540000	X
anesthj-33	127	2	.	.	PUNCT
anesthj-33	127	3	updated	update	VERB
anesthj-33	127	4	january	january	PROPN
anesthj-33	127	5	2015	2015	NUM
anesthj-33	127	6	.	.	PUNCT
anesthj-33	128	1	accessed	access	VERB
anesthj-33	128	2	march	march	PROPN
anesthj-33	128	3	8	8	NUM
anesthj-33	128	4	,	,	PUNCT
anesthj-33	128	5	2015	2015	NUM
anesthj-33	128	6	.	.	PUNCT
anesthj-33	129	1	10	10	NUM
anesthj-33	129	2	.	.	PUNCT
anesthj-33	130	1	shipton	shipton	PROPN
anesthj-33	130	2	ea	ea	PROPN
anesthj-33	130	3	.	.	PUNCT
anesthj-33	131	1	the	the	DET
anesthj-33	131	2	perioperative	perioperative	ADJ
anesthj-33	131	3	anaesthetic	anaesthetic	ADJ
anesthj-33	131	4	management	management	NOUN
anesthj-33	131	5	of	of	ADP
anesthj-33	131	6	patients	patient	NOUN
anesthj-33	131	7	with	with	ADP
anesthj-33	131	8	mitochondrial	mitochondrial	ADJ
anesthj-33	131	9	myopathies	myopathy	NOUN
anesthj-33	131	10	.	.	PUNCT
anesthj-33	132	1	cpd	cpd	PROPN
anesthj-33	132	2	anaesth	anaesth	PROPN
anesthj-33	132	3	.	.	PUNCT
anesthj-33	133	1	2006;8(1	2006;8(1	NOUN
anesthj-33	133	2	):	):	PUNCT
anesthj-33	133	3	03	03	NUM
anesthj-33	133	4	-	-	SYM
anesthj-33	133	5	09	09	NUM
anesthj-33	133	6	.	.	PUNCT
anesthj-33	134	1	11	11	NUM
anesthj-33	134	2	.	.	PUNCT
anesthj-33	135	1	sasano	sasano	PROPN
anesthj-33	135	2	n	n	CCONJ
anesthj-33	135	3	,	,	PUNCT
anesthj-33	135	4	fujita	fujita	PROPN
anesthj-33	135	5	y	y	PROPN
anesthj-33	135	6	,	,	PUNCT
anesthj-33	135	7	so	so	PROPN
anesthj-33	135	8	mh	mh	PROPN
anesthj-33	135	9	,	,	PUNCT
anesthj-33	135	10	sobue	sobue	PROPN
anesthj-33	135	11	k	k	PROPN
anesthj-33	135	12	,	,	PUNCT
anesthj-33	135	13	sasano	sasano	PROPN
anesthj-33	135	14	h	h	NOUN
anesthj-33	135	15	,	,	PUNCT
anesthj-33	135	16	katsuya	katsuya	PROPN
anesthj-33	135	17	h.	h.	PROPN
anesthj-33	135	18	anesthetic	anesthetic	PROPN
anesthj-33	135	19	management	management	NOUN
anesthj-33	135	20	of	of	ADP
anesthj-33	135	21	a	a	DET
anesthj-33	135	22	patient	patient	NOUN
anesthj-33	135	23	with	with	ADP
anesthj-33	135	24	mitochondrial	mitochondrial	ADJ
anesthj-33	135	25	myopathy	myopathy	ADJ
anesthj-33	135	26	,	,	PUNCT
anesthj-33	135	27	encephalopathy	encephalopathy	ADJ
anesthj-33	135	28	,	,	PUNCT
anesthj-33	135	29	lactic	lactic	ADJ
anesthj-33	135	30	acidosis	acidosis	NOUN
anesthj-33	135	31	,	,	PUNCT
anesthj-33	135	32	and	and	CCONJ
anesthj-33	135	33	stroke	stroke	NOUN
anesthj-33	135	34	-	-	PUNCT
anesthj-33	135	35	like	like	ADJ
anesthj-33	135	36	episodes	episode	NOUN
anesthj-33	135	37	(	(	PUNCT
anesthj-33	135	38	melas	mela	NOUN
anesthj-33	135	39	)	)	PUNCT
anesthj-33	135	40	.	.	PUNCT
anesthj-33	136	1	j	j	PROPN
anesthj-33	136	2	anesth	anesth	PROPN
anesthj-33	136	3	.	.	PUNCT
anesthj-33	137	1	2007;21(1):72	2007;21(1):72	NUM
anesthj-33	137	2	-	-	SYM
anesthj-33	137	3	75	75	NUM
anesthj-33	137	4	.	.	PUNCT
anesthj-33	138	1	http://dx.doi	http://dx.doi	NOUN
anesthj-33	138	2	.	.	PUNCT
anesthj-33	139	1	org/10.1007	org/10.1007	PROPN
anesthj-33	139	2	/	/	SYM
anesthj-33	139	3	s00540	s00540	PROPN
anesthj-33	139	4	-	-	PUNCT
anesthj-33	139	5	006	006	NUM
anesthj-33	139	6	-	-	PUNCT
anesthj-33	139	7	0449	0449	NUM
anesthj-33	139	8	-	-	PUNCT
anesthj-33	139	9	y.	y.	PROPN
anesthj-33	139	10	12	12	NUM
anesthj-33	139	11	.	.	PUNCT
anesthj-33	140	1	klingler	klingler	PROPN
anesthj-33	140	2	w	w	PROPN
anesthj-33	140	3	,	,	PUNCT
anesthj-33	140	4	lehmann	lehmann	NOUN
anesthj-33	140	5	-	-	PUNCT
anesthj-33	140	6	horn	horn	PROPN
anesthj-33	140	7	f	f	PROPN
anesthj-33	140	8	,	,	PUNCT
anesthj-33	140	9	jurkat	jurkat	PROPN
anesthj-33	140	10	-	-	PUNCT
anesthj-33	140	11	rott	rott	PROPN
anesthj-33	140	12	k.	k.	PROPN
anesthj-33	140	13	complications	complication	NOUN
anesthj-33	140	14	of	of	ADP
anesthj-33	140	15	anaesthesia	anaesthesia	NOUN
anesthj-33	140	16	in	in	ADP
anesthj-33	140	17	neuromuscular	neuromuscular	ADJ
anesthj-33	140	18	disorders	disorder	NOUN
anesthj-33	140	19	.	.	PUNCT
anesthj-33	141	1	neuromuscul	neuromuscul	PROPN
anesthj-33	141	2	disord	disord	PROPN
anesthj-33	141	3	.	.	PUNCT
anesthj-33	142	1	2005;15(3):195	2005;15(3):195	NUM
anesthj-33	142	2	-	-	SYM
anesthj-33	142	3	206	206	NUM
anesthj-33	142	4	.	.	PUNCT
anesthj-33	143	1	http://dx.doi.org/10.1016/j.nmd.2004.10.017	http://dx.doi.org/10.1016/j.nmd.2004.10.017	NOUN
anesthj-33	143	2	.	.	PUNCT
anesthj-33	144	1	13	13	NUM
anesthj-33	144	2	.	.	PUNCT
anesthj-33	144	3	malignant	malignant	ADJ
anesthj-33	144	4	hyperthermia	hyperthermia	PROPN
anesthj-33	144	5	association	association	NOUN
anesthj-33	144	6	of	of	ADP
anesthj-33	144	7	the	the	DET
anesthj-33	144	8	united	united	PROPN
anesthj-33	144	9	states	states	PROPN
anesthj-33	144	10	.	.	PUNCT
anesthj-33	145	1	does	do	AUX
anesthj-33	145	2	mitochondrial	mitochondrial	ADJ
anesthj-33	145	3	myopathy	myopathy	ADJ
anesthj-33	145	4	(	(	PUNCT
anesthj-33	145	5	mm	mm	NOUN
anesthj-33	145	6	)	)	PUNCT
anesthj-33	145	7	increase	increase	NOUN
anesthj-33	145	8	an	an	DET
anesthj-33	145	9	individual	individual	NOUN
anesthj-33	145	10	’s	’s	PART
anesthj-33	145	11	susceptibility	susceptibility	NOUN
anesthj-33	145	12	to	to	PART
anesthj-33	145	13	malignant	malignant	ADJ
anesthj-33	145	14	hyperthermia	hyperthermia	NOUN
anesthj-33	145	15	(	(	PUNCT
anesthj-33	145	16	mh	mh	PROPN
anesthj-33	145	17	)	)	PUNCT
anesthj-33	145	18	?	?	PUNCT
anesthj-33	146	1	malignant	malignant	ADJ
anesthj-33	146	2	hyperthermia	hyperthermia	PROPN
anesthj-33	146	3	association	association	NOUN
anesthj-33	146	4	of	of	ADP
anesthj-33	146	5	the	the	DET
anesthj-33	146	6	united	united	PROPN
anesthj-33	146	7	states	states	PROPN
anesthj-33	146	8	website	website	NOUN
anesthj-33	146	9	.	.	PUNCT
anesthj-33	147	1	http://	http://	PROPN
anesthj-33	147	2	www.mhaus.org/healthcare-professionals/mhaus-recommendations/mitochondrial-myopathy	www.mhaus.org/healthcare-professionals/mhaus-recommendations/mitochondrial-myopathy	ADJ
anesthj-33	147	3	.	.	PUNCT
anesthj-33	148	1	accessed	access	VERB
anesthj-33	148	2	march	march	PROPN
anesthj-33	148	3	8	8	NUM
anesthj-33	148	4	,	,	PUNCT
anesthj-33	148	5	2015	2015	NUM
anesthj-33	148	6	.	.	PUNCT
anesthj-33	149	1	14	14	NUM
anesthj-33	149	2	.	.	X
anesthj-33	150	1	litman	litman	NOUN
anesthj-33	150	2	rs	rs	PROPN
anesthj-33	150	3	.	.	PUNCT
anesthj-33	151	1	mh	mh	PROPN
anesthj-33	151	2	-	-	PUNCT
anesthj-33	151	3	associated	associate	VERB
anesthj-33	151	4	diseases	disease	NOUN
anesthj-33	151	5	:	:	PUNCT
anesthj-33	151	6	who	who	PRON
anesthj-33	151	7	really	really	ADV
anesthj-33	151	8	needs	need	VERB
anesthj-33	151	9	a	a	DET
anesthj-33	151	10	non	non	ADJ
anesthj-33	151	11	-	-	ADJ
anesthj-33	151	12	triggering	trigger	VERB
anesthj-33	151	13	technique	technique	NOUN
anesthj-33	151	14	?	?	PUNCT
anesthj-33	152	1	semin	semin	PROPN
anesthj-33	152	2	anesth	anesth	PROPN
anesthj-33	152	3	.	.	PUNCT
anesthj-33	153	1	2007;26(3):113	2007;26(3):113	PROPN
anesthj-33	153	2	-	-	PUNCT
anesthj-33	153	3	119	119	NUM
anesthj-33	153	4	.	.	PUNCT
anesthj-33	154	1	http://	http://	PROPN
anesthj-33	154	2	dx.doi.org/10.1053/j.sane.2007.06.007	dx.doi.org/10.1053/j.sane.2007.06.007	NOUN
anesthj-33	154	3	.	.	PROPN
anesthj-33	155	1	15	15	NUM
anesthj-33	155	2	.	.	PUNCT
anesthj-33	156	1	song	song	PROPN
anesthj-33	156	2	s	s	PROPN
anesthj-33	156	3	,	,	PUNCT
anesthj-33	156	4	niezgoda	niezgoda	PROPN
anesthj-33	156	5	j	j	PROPN
anesthj-33	156	6	,	,	PUNCT
anesthj-33	156	7	parikh	parikh	PROPN
anesthj-33	156	8	s.	s.	PROPN
anesthj-33	156	9	effects	effect	NOUN
anesthj-33	156	10	of	of	ADP
anesthj-33	156	11	anesthesia	anesthesia	NOUN
anesthj-33	156	12	in	in	ADP
anesthj-33	156	13	patients	patient	NOUN
anesthj-33	156	14	with	with	ADP
anesthj-33	156	15	primary	primary	ADJ
anesthj-33	156	16	mitochondrial	mitochondrial	ADJ
anesthj-33	156	17	disorders	disorder	NOUN
anesthj-33	156	18	.	.	PUNCT
anesthj-33	157	1	mitochondrion	mitochondrion	NOUN
anesthj-33	157	2	.	.	PUNCT
anesthj-33	158	1	2013;13(6):908	2013;13(6):908	NOUN
anesthj-33	158	2	.	.	PUNCT
anesthj-33	159	1	http://dx.doi.org/10.1016/j.mito.2013.07.029	http://dx.doi.org/10.1016/j.mito.2013.07.029	PROPN
anesthj-33	159	2	.	.	PUNCT
anesthj-33	160	1	16	16	NUM
anesthj-33	160	2	.	.	PUNCT
anesthj-33	161	1	moreira	moreira	PROPN
anesthj-33	161	2	a	a	DET
anesthj-33	161	3	,	,	PUNCT
anesthj-33	161	4	silva	silva	PROPN
anesthj-33	161	5	a	a	PROPN
anesthj-33	161	6	,	,	PUNCT
anesthj-33	161	7	antunes	antunes	PROPN
anesthj-33	161	8	m	m	PROPN
anesthj-33	161	9	,	,	PUNCT
anesthj-33	161	10	neves	neve	NOUN
anesthj-33	161	11	i	i	PROPN
anesthj-33	161	12	,	,	PUNCT
anesthj-33	161	13	costa	costa	PROPN
anesthj-33	161	14	c	c	PROPN
anesthj-33	161	15	,	,	PUNCT
anesthj-33	161	16	santos	santos	PROPN
anesthj-33	161	17	p.	p.	PROPN
anesthj-33	161	18	anaesthesia	anaesthesia	PROPN
anesthj-33	161	19	in	in	ADP
anesthj-33	161	20	patients	patient	NOUN
anesthj-33	161	21	with	with	ADP
anesthj-33	161	22	mitochondrial	mitochondrial	ADJ
anesthj-33	161	23	cytopathy	cytopathy	NOUN
anesthj-33	161	24	:	:	PUNCT
anesthj-33	161	25	6	6	NUM
anesthj-33	161	26	years	year	NOUN
anesthj-33	161	27	series	series	PROPN
anesthj-33	161	28	review	review	PROPN
anesthj-33	161	29	.	.	PUNCT
anesthj-33	162	1	eur	eur	PROPN
anesthj-33	162	2	j	j	PROPN
anesthj-33	162	3	anaesthesiol	anaesthesiol	PROPN
anesthj-33	162	4	suppl	suppl	PROPN
anesthj-33	162	5	.	.	PUNCT
anesthj-33	163	1	2014;31:258	2014;31:258	X
anesthj-33	163	2	-	-	SYM
anesthj-33	163	3	259	259	NUM
anesthj-33	163	4	.	.	PUNCT
anesthj-33	164	1	http://dx.doi.org/10.1097/00003643-201406001-00746	http://dx.doi.org/10.1097/00003643-201406001-00746	PROPN
anesthj-33	164	2	.	.	PUNCT
anesthj-33	164	3	17	17	NUM
anesthj-33	164	4	.	.	PUNCT
anesthj-33	164	5	footitt	footitt	VERB
anesthj-33	164	6	ej	ej	PROPN
anesthj-33	164	7	,	,	PUNCT
anesthj-33	164	8	sinha	sinha	PROPN
anesthj-33	164	9	md	md	PROPN
anesthj-33	164	10	,	,	PUNCT
anesthj-33	164	11	raiman	raiman	PROPN
anesthj-33	164	12	jaj	jaj	PROPN
anesthj-33	164	13	,	,	PUNCT
anesthj-33	164	14	dhawan	dhawan	PROPN
anesthj-33	164	15	a	a	PRON
anesthj-33	164	16	,	,	PUNCT
anesthj-33	164	17	moganasundram	moganasundram	PROPN
anesthj-33	164	18	s	s	PROPN
anesthj-33	164	19	,	,	PUNCT
anesthj-33	164	20	champion	champion	PROPN
anesthj-33	164	21	mp	mp	PROPN
anesthj-33	164	22	.	.	PROPN
anesthj-33	164	23	mitochondrial	mitochondrial	ADJ
anesthj-33	164	24	disorders	disorder	NOUN
anesthj-33	164	25	and	and	CCONJ
anesthj-33	164	26	general	general	ADJ
anesthj-33	164	27	anesthesia	anesthesia	NOUN
anesthj-33	164	28	:	:	PUNCT
anesthj-33	164	29	a	a	DET
anesthj-33	164	30	case	case	NOUN
anesthj-33	164	31	series	series	NOUN
anesthj-33	164	32	and	and	CCONJ
anesthj-33	164	33	review	review	NOUN
anesthj-33	164	34	.	.	PUNCT
anesthj-33	165	1	br	br	PROPN
anesthj-33	165	2	j	j	PROPN
anesthj-33	165	3	anaesth	anaesth	PROPN
anesthj-33	165	4	.	.	PUNCT
anesthj-33	166	1	2008;100(4):436	2008;100(4):436	NUM
anesthj-33	166	2	-	-	SYM
anesthj-33	166	3	441	441	NUM
anesthj-33	166	4	.	.	PUNCT
anesthj-33	167	1	http://dx.doi.org/10.1093/bja/aen014	http://dx.doi.org/10.1093/bja/aen014	PROPN
anesthj-33	167	2	.	.	PROPN
anesthj-33	167	3	18	18	NUM
anesthj-33	167	4	.	.	PUNCT
anesthj-33	168	1	thompson	thompson	PROPN
anesthj-33	168	2	va	va	PROPN
anesthj-33	168	3	,	,	PUNCT
anesthj-33	168	4	wahr	wahr	PROPN
anesthj-33	168	5	ja	ja	PROPN
anesthj-33	168	6	.	.	PUNCT
anesthj-33	169	1	anesthetic	anesthetic	ADJ
anesthj-33	169	2	considerations	consideration	NOUN
anesthj-33	169	3	in	in	ADP
anesthj-33	169	4	patients	patient	NOUN
anesthj-33	169	5	presenting	present	VERB
anesthj-33	169	6	with	with	ADP
anesthj-33	169	7	mitochondrial	mitochondrial	ADJ
anesthj-33	169	8	myopathy	myopathy	ADJ
anesthj-33	169	9	,	,	PUNCT
anesthj-33	169	10	encephalopathy	encephalopathy	ADJ
anesthj-33	169	11	,	,	PUNCT
anesthj-33	169	12	lactic	lactic	ADJ
anesthj-33	169	13	acidosis	acidosis	NOUN
anesthj-33	169	14	,	,	PUNCT
anesthj-33	169	15	and	and	CCONJ
anesthj-33	169	16	stroke	stroke	NOUN
anesthj-33	169	17	-	-	PUNCT
anesthj-33	169	18	like	like	ADJ
anesthj-33	169	19	episodes	episode	NOUN
anesthj-33	169	20	(	(	PUNCT
anesthj-33	169	21	melas	melas	NOUN
anesthj-33	169	22	)	)	PUNCT
anesthj-33	169	23	syndrome	syndrome	NOUN
anesthj-33	169	24	.	.	PUNCT
anesthj-33	170	1	anesth	anesth	PROPN
anesthj-33	170	2	analg	analg	PROPN
anesthj-33	170	3	.	.	PUNCT
anesthj-33	171	1	1997;85:1404	1997;85:1404	NUM
anesthj-33	171	2	-	-	SYM
anesthj-33	171	3	1406	1406	NUM
anesthj-33	171	4	.	.	PUNCT
anesthj-33	172	1	19	19	NUM
anesthj-33	172	2	.	.	X
anesthj-33	172	3	maurtua	maurtua	PROPN
anesthj-33	172	4	m	m	PROPN
anesthj-33	172	5	,	,	PUNCT
anesthj-33	172	6	torres	torre	VERB
anesthj-33	172	7	a	a	PRON
anesthj-33	172	8	,	,	PUNCT
anesthj-33	172	9	ibarra	ibarra	PROPN
anesthj-33	172	10	v	v	PROPN
anesthj-33	172	11	,	,	PUNCT
anesthj-33	172	12	deboer	deboer	PROPN
anesthj-33	172	13	j	j	PROPN
anesthj-33	172	14	,	,	PUNCT
anesthj-33	172	15	dolak	dolak	VERB
anesthj-33	172	16	j.	j.	PROPN
anesthj-33	172	17	anesthetic	anesthetic	PROPN
anesthj-33	172	18	management	management	NOUN
anesthj-33	172	19	of	of	ADP
anesthj-33	172	20	an	an	DET
anesthj-33	172	21	obstetric	obstetric	ADJ
anesthj-33	172	22	patient	patient	NOUN
anesthj-33	172	23	with	with	ADP
anesthj-33	172	24	melas	melas	PROPN
anesthj-33	172	25	syndrome	syndrome	NOUN
anesthj-33	172	26	:	:	PUNCT
anesthj-33	172	27	case	case	NOUN
anesthj-33	172	28	report	report	NOUN
anesthj-33	172	29	and	and	CCONJ
anesthj-33	172	30	literature	literature	NOUN
anesthj-33	172	31	review	review	PROPN
anesthj-33	172	32	.	.	PUNCT
anesthj-33	173	1	int	int	PROPN
anesthj-33	173	2	j	j	PROPN
anesthj-33	173	3	obstet	obstet	PROPN
anesthj-33	173	4	anesth	anesth	PROPN
anesthj-33	173	5	.	.	PUNCT
anesthj-33	174	1	2008;17(4):370	2008;17(4):370	NUM
anesthj-33	174	2	-	-	SYM
anesthj-33	174	3	373	373	NUM
anesthj-33	174	4	.	.	PUNCT
anesthj-33	175	1	http://dx.doi.org/10.1016/j.ijoa.2007.11.011	http://dx.doi.org/10.1016/j.ijoa.2007.11.011	NOUN
anesthj-33	175	2	.	.	PUNCT
anesthj-33	176	1	20	20	NUM
anesthj-33	176	2	.	.	PUNCT
anesthj-33	176	3	finsterer	finsterer	PROPN
anesthj-33	176	4	j	j	PROPN
anesthj-33	176	5	,	,	PUNCT
anesthj-33	176	6	segall	segall	PROPN
anesthj-33	176	7	l.	l.	PROPN
anesthj-33	176	8	drugs	drugs	PROPN
anesthj-33	176	9	interfering	interfere	VERB
anesthj-33	176	10	with	with	ADP
anesthj-33	176	11	mitochondrial	mitochondrial	ADJ
anesthj-33	176	12	disorders	disorder	NOUN
anesthj-33	176	13	.	.	PUNCT
anesthj-33	177	1	drug	drug	NOUN
anesthj-33	177	2	chem	chem	NOUN
anesthj-33	177	3	toxicol	toxicol	NOUN
anesthj-33	177	4	.	.	PUNCT
anesthj-33	178	1	2010;33(2):138	2010;33(2):138	PROPN
anesthj-33	178	2	-	-	SYM
anesthj-33	178	3	151	151	NUM
anesthj-33	178	4	.	.	PUNCT
anesthj-33	179	1	http://dx.doi	http://dx.doi	NOUN
anesthj-33	179	2	.	.	PUNCT
anesthj-33	180	1	org/10.3109/01480540903207076	org/10.3109/01480540903207076	PROPN
anesthj-33	180	2	.	.	PUNCT
anesthj-33	181	1	21	21	NUM
anesthj-33	181	2	.	.	PUNCT
anesthj-33	182	1	park	park	PROPN
anesthj-33	182	2	js	js	PROPN
anesthj-33	182	3	,	,	PUNCT
anesthj-33	182	4	baek	baek	PROPN
anesthj-33	182	5	cw	cw	PROPN
anesthj-33	182	6	,	,	PUNCT
anesthj-33	182	7	kang	kang	PROPN
anesthj-33	182	8	h	h	PROPN
anesthj-33	182	9	,	,	PUNCT
anesthj-33	182	10	et	et	PROPN
anesthj-33	182	11	al	al	PROPN
anesthj-33	182	12	.	.	PROPN
anesthj-33	182	13	total	total	PROPN
anesthj-33	182	14	intravenous	intravenous	ADJ
anesthj-33	182	15	anesthesia	anesthesia	NOUN
anesthj-33	182	16	with	with	ADP
anesthj-33	182	17	propofol	propofol	NOUN
anesthj-33	182	18	and	and	CCONJ
anesthj-33	182	19	remifentanil	remifentanil	NOUN
anesthj-33	182	20	in	in	ADP
anesthj-33	182	21	a	a	DET
anesthj-33	182	22	patient	patient	NOUN
anesthj-33	182	23	with	with	ADP
anesthj-33	182	24	melas	melas	PROPN
anesthj-33	182	25	syndrome	syndrome	PROPN
anesthj-33	182	26	-	-	PUNCT
anesthj-33	182	27	a	a	DET
anesthj-33	182	28	case	case	NOUN
anesthj-33	182	29	report	report	NOUN
anesthj-33	182	30	.	.	PUNCT
anesthj-33	183	1	korean	korean	PROPN
anesthj-33	183	2	j	j	PROPN
anesthj-33	183	3	anesthesiol	anesthesiol	PROPN
anesthj-33	183	4	.	.	PUNCT
anesthj-33	184	1	2010;58(4):409	2010;58(4):409	NUM
anesthj-33	184	2	-	-	SYM
anesthj-33	184	3	412	412	NUM
anesthj-33	184	4	.	.	PUNCT
anesthj-33	185	1	http://dx.doi.org/10.4097/kjae.2010.58.4.409	http://dx.doi.org/10.4097/kjae.2010.58.4.409	PROPN
anesthj-33	185	2	.	.	PROPN
anesthj-33	185	3	22	22	NUM
anesthj-33	185	4	.	.	PUNCT
anesthj-33	186	1	aouad	aouad	PROPN
anesthj-33	186	2	mt	mt	PROPN
anesthj-33	186	3	,	,	PUNCT
anesthj-33	186	4	gerges	gerge	VERB
anesthj-33	186	5	fj	fj	PROPN
anesthj-33	186	6	,	,	PUNCT
anesthj-33	186	7	baraka	baraka	VERB
anesthj-33	186	8	as	as	ADP
anesthj-33	186	9	.	.	PUNCT
anesthj-33	186	10	resistance	resistance	NOUN
anesthj-33	186	11	to	to	PART
anesthj-33	186	12	cisatracurium	cisatracurium	VERB
anesthj-33	186	13	in	in	ADP
anesthj-33	186	14	a	a	DET
anesthj-33	186	15	patient	patient	NOUN
anesthj-33	186	16	with	with	ADP
anesthj-33	186	17	melas	melas	PROPN
anesthj-33	186	18	syndrome	syndrome	PROPN
anesthj-33	186	19	.	.	PUNCT
anesthj-33	187	1	paediatr	paediatr	NOUN
anesthj-33	187	2	anaesth	anaesth	PROPN
anesthj-33	187	3	.	.	PUNCT
anesthj-33	188	1	2005;15:1124	2005;15:1124	NUM
anesthj-33	188	2	-	-	SYM
anesthj-33	188	3	1127	1127	NUM
anesthj-33	188	4	.	.	PUNCT
anesthj-33	189	1	23	23	NUM
anesthj-33	189	2	.	.	PUNCT
anesthj-33	189	3	blair	blair	PROPN
anesthj-33	189	4	mt	mt	PROPN
anesthj-33	189	5	,	,	PUNCT
anesthj-33	189	6	heard	hear	VERB
anesthj-33	189	7	g.	g.	PROPN
anesthj-33	189	8	neuraxial	neuraxial	PROPN
anesthj-33	189	9	anesthesia	anesthesia	PROPN
anesthj-33	189	10	in	in	ADP
anesthj-33	189	11	melas	melas	PROPN
anesthj-33	189	12	syndrome	syndrome	PROPN
anesthj-33	189	13	.	.	PUNCT
anesthj-33	190	1	anaesth	anaesth	PROPN
anesthj-33	190	2	intensive	intensive	ADJ
anesthj-33	190	3	care	care	NOUN
anesthj-33	190	4	.	.	PUNCT
anesthj-33	191	1	2011;39(6):1152	2011;39(6):1152	NUM
anesthj-33	191	2	-	-	PUNCT
anesthj-33	191	3	1153	1153	NUM
anesthj-33	191	4	.	.	PUNCT
anesthj-33	192	1	24	24	NUM
anesthj-33	192	2	.	.	PUNCT
anesthj-33	193	1	hsiao	hsiao	PROPN
anesthj-33	193	2	p	p	PROPN
anesthj-33	193	3	,	,	PUNCT
anesthj-33	193	4	cheng	cheng	PROPN
anesthj-33	193	5	y	y	PROPN
anesthj-33	193	6	,	,	PUNCT
anesthj-33	193	7	hsiang	hsiang	PROPN
anesthj-33	193	8	-	-	PUNCT
anesthj-33	193	9	chiang	chiang	PROPN
anesthj-33	193	10	t	t	PROPN
anesthj-33	193	11	,	,	PUNCT
anesthj-33	193	12	chuang	chuang	PROPN
anesthj-33	193	13	y	y	PROPN
anesthj-33	193	14	,	,	PUNCT
anesthj-33	193	15	kao	kao	PROPN
anesthj-33	193	16	p	p	PROPN
anesthj-33	193	17	,	,	PUNCT
anesthj-33	193	18	tsai	tsai	PROPN
anesthj-33	193	19	s.	s.	PROPN
anesthj-33	193	20	spinal	spinal	PROPN
anesthj-33	193	21	anesthesia	anesthesia	PROPN
anesthj-33	193	22	in	in	ADP
anesthj-33	193	23	melas	melas	PROPN
anesthj-33	193	24	syndrome	syndrome	PROPN
anesthj-33	193	25	:	:	PUNCT
anesthj-33	193	26	a	a	DET
anesthj-33	193	27	case	case	NOUN
anesthj-33	193	28	with	with	ADP
anesthj-33	193	29	mitochondrial	mitochondrial	ADJ
anesthj-33	193	30	myopathy	myopathy	ADJ
anesthj-33	193	31	,	,	PUNCT
anesthj-33	193	32	encephalopathy	encephalopathy	ADJ
anesthj-33	193	33	,	,	PUNCT
anesthj-33	193	34	lactic	lactic	ADJ
anesthj-33	193	35	acidosis	acidosis	NOUN
anesthj-33	193	36	,	,	PUNCT
anesthj-33	193	37	and	and	CCONJ
anesthj-33	193	38	stroke	stroke	NOUN
anesthj-33	193	39	-	-	PUNCT
anesthj-33	193	40	like	like	ADJ
anesthj-33	193	41	episodes	episode	NOUN
anesthj-33	193	42	.	.	PUNCT
anesthj-33	194	1	acta	acta	PROPN
anesthj-33	194	2	anaesthesiol	anaesthesiol	PROPN
anesthj-33	194	3	sin	sin	PROPN
anesthj-33	194	4	.	.	PUNCT
anesthj-33	195	1	2000;38:107	2000;38:107	X
anesthj-33	195	2	-	-	SYM
anesthj-33	195	3	110	110	NUM
anesthj-33	195	4	.	.	PUNCT
anesthj-33	196	1	25	25	NUM
anesthj-33	196	2	.	.	PUNCT
anesthj-33	197	1	bolton	bolton	PROPN
anesthj-33	197	2	p	p	PROPN
anesthj-33	197	3	,	,	PUNCT
anesthj-33	197	4	peutrell	peutrell	PROPN
anesthj-33	197	5	j	j	PROPN
anesthj-33	197	6	,	,	PUNCT
anesthj-33	197	7	zuberi	zuberi	PROPN
anesthj-33	197	8	s	s	PROPN
anesthj-33	197	9	,	,	PUNCT
anesthj-33	197	10	robinson	robinson	PROPN
anesthj-33	197	11	p.	p.	PROPN
anesthj-33	197	12	anaesthesia	anaesthesia	PROPN
anesthj-33	197	13	for	for	ADP
anesthj-33	197	14	an	an	DET
anesthj-33	197	15	adolescent	adolescent	NOUN
anesthj-33	197	16	with	with	ADP
anesthj-33	197	17	mitochondrial	mitochondrial	ADJ
anesthj-33	197	18	encephalomyopathylactic	encephalomyopathylactic	ADJ
anesthj-33	197	19	acidosis	acidosis	NOUN
anesthj-33	197	20	-	-	PUNCT
anesthj-33	197	21	stroke	stroke	NOUN
anesthj-33	197	22	-	-	PUNCT
anesthj-33	197	23	like	like	ADJ
anesthj-33	197	24	episodes	episode	NOUN
anesthj-33	197	25	syndrome	syndrome	NOUN
anesthj-33	197	26	.	.	PUNCT
anesthj-33	198	1	paediatr	paediatr	NOUN
anesthj-33	198	2	anaesth	anaesth	PROPN
anesthj-33	198	3	.	.	PUNCT
anesthj-33	199	1	2003;13(5):453	2003;13(5):453	PROPN
anesthj-33	199	2	-	-	PUNCT
anesthj-33	199	3	456	456	NUM
anesthj-33	199	4	.	.	PUNCT
anesthj-33	200	1	http://dx.doi.org/10.1046/j.14609592.2003.01001.x	http://dx.doi.org/10.1046/j.14609592.2003.01001.x	X
anesthj-33	200	2	.	.	PUNCT
anesthj-33	201	1	26	26	NUM
anesthj-33	201	2	.	.	PUNCT
anesthj-33	202	1	gentili	gentili	PROPN
anesthj-33	202	2	me	i	PRON
anesthj-33	202	3	,	,	PUNCT
anesthj-33	202	4	raud	raud	VERB
anesthj-33	202	5	c	c	PROPN
anesthj-33	202	6	,	,	PUNCT
anesthj-33	202	7	enel	enel	PROPN
anesthj-33	202	8	d	d	PROPN
anesthj-33	202	9	,	,	PUNCT
anesthj-33	202	10	henot	henot	PROPN
anesthj-33	202	11	m	m	PROPN
anesthj-33	202	12	,	,	PUNCT
anesthj-33	202	13	bothereau	bothereau	PROPN
anesthj-33	202	14	h.	h.	PROPN
anesthj-33	202	15	combination	combination	NOUN
anesthj-33	202	16	of	of	ADP
anesthj-33	202	17	general	general	ADJ
anesthj-33	202	18	anaesthesia	anaesthesia	NOUN
anesthj-33	202	19	and	and	CCONJ
anesthj-33	202	20	postoperative	postoperative	ADJ
anesthj-33	202	21	epidural	epidural	ADJ
anesthj-33	202	22	analgesia	analgesia	NOUN
anesthj-33	202	23	in	in	ADP
anesthj-33	202	24	mitochondrial	mitochondrial	ADJ
anesthj-33	202	25	myopathy	myopathy	NOUN
anesthj-33	202	26	.	.	PUNCT
anesthj-33	203	1	ann	ann	PROPN
anesthj-33	203	2	fr	fr	PROPN
anesthj-33	203	3	anesth	anesth	VERB
anesthj-33	203	4	reanim	reanim	NOUN
anesthj-33	203	5	.	.	PUNCT
anesthj-33	204	1	2013;32(10):e149	2013;32(10):e149	NOUN
anesthj-33	204	2	.	.	PUNCT
anesthj-33	205	1	http://dx.doi.org/10.1016/j.annfar.2013.07.798	http://dx.doi.org/10.1016/j.annfar.2013.07.798	PROPN
anesthj-33	205	2	.	.	PROPN
anesthj-33	206	1	27	27	NUM
anesthj-33	206	2	.	.	PUNCT
anesthj-33	207	1	nouette	nouette	NOUN
anesthj-33	207	2	-	-	PUNCT
anesthj-33	207	3	gaulain	gaulain	NOUN
anesthj-33	207	4	k	k	PROPN
anesthj-33	207	5	,	,	PUNCT
anesthj-33	207	6	jose	jose	PROPN
anesthj-33	207	7	c	c	PROPN
anesthj-33	207	8	,	,	PUNCT
anesthj-33	207	9	capdevila	capdevila	NOUN
anesthj-33	207	10	x	x	NOUN
anesthj-33	207	11	,	,	PUNCT
anesthj-33	207	12	rossignol	rossignol	PROPN
anesthj-33	207	13	r.	r.	PROPN
anesthj-33	207	14	from	from	ADP
anesthj-33	207	15	analgesia	analgesia	PROPN
anesthj-33	207	16	to	to	ADP
anesthj-33	207	17	myopathy	myopathy	ADJ
anesthj-33	207	18	:	:	PUNCT
anesthj-33	207	19	when	when	SCONJ
anesthj-33	207	20	local	local	ADJ
anesthj-33	207	21	anesthetics	anesthetic	NOUN
anesthj-33	207	22	impair	impair	VERB
anesthj-33	207	23	the	the	DET
anesthj-33	207	24	mitochondrion	mitochondrion	NOUN
anesthj-33	207	25	.	.	PUNCT
anesthj-33	208	1	int	int	PROPN
anesthj-33	208	2	j	j	PROPN
anesthj-33	208	3	biochem	biochem	PROPN
anesthj-33	208	4	cell	cell	NOUN
anesthj-33	208	5	biol	biol	PROPN
anesthj-33	208	6	.	.	PUNCT
anesthj-33	209	1	2011;43(1):14	2011;43(1):14	NUM
anesthj-33	209	2	-	-	SYM
anesthj-33	209	3	19	19	NUM
anesthj-33	209	4	.	.	PUNCT
anesthj-33	210	1	http://dx.doi.org/10.1016/j.biocel.2010.10.005	http://dx.doi.org/10.1016/j.biocel.2010.10.005	PROPN
anesthj-33	210	2	.	.	PUNCT
anesthj-33	211	1	28	28	NUM
anesthj-33	211	2	.	.	PUNCT
anesthj-33	212	1	kanabus	kanabus	PROPN
anesthj-33	212	2	m	m	PROPN
anesthj-33	212	3	,	,	PUNCT
anesthj-33	212	4	heales	heale	NOUN
anesthj-33	212	5	sj	sj	PROPN
anesthj-33	212	6	,	,	PUNCT
anesthj-33	212	7	rahman	rahman	PROPN
anesthj-33	212	8	s.	s.	PROPN
anesthj-33	212	9	development	development	PROPN
anesthj-33	212	10	of	of	ADP
anesthj-33	212	11	pharmacological	pharmacological	ADJ
anesthj-33	212	12	strategies	strategy	NOUN
anesthj-33	212	13	for	for	ADP
anesthj-33	212	14	mitochondrial	mitochondrial	ADJ
anesthj-33	212	15	disorders	disorder	NOUN
anesthj-33	212	16	.	.	PUNCT
anesthj-33	213	1	br	br	PROPN
anesthj-33	213	2	j	j	PROPN
anesthj-33	213	3	pharmacol	pharmacol	PROPN
anesthj-33	213	4	.	.	PUNCT
anesthj-33	214	1	2014;171(8):1798	2014;171(8):1798	NUM
anesthj-33	214	2	-	-	SYM
anesthj-33	214	3	1817	1817	NUM
anesthj-33	214	4	.	.	PUNCT
anesthj-33	215	1	http://dx.doi.org/10.1111/bph.12456	http://dx.doi.org/10.1111/bph.12456	PROPN
anesthj-33	215	2	.	.	PUNCT
anesthj-33	216	1	summary	summary	NOUN
anesthj-33	216	2	of	of	ADP
anesthj-33	216	3	key	key	ADJ
anesthj-33	216	4	points	point	NOUN
anesthj-33	216	5	melas	mela	NOUN
anesthj-33	216	6	is	be	AUX
anesthj-33	216	7	a	a	DET
anesthj-33	216	8	mitochondrial	mitochondrial	ADJ
anesthj-33	216	9	disorder	disorder	NOUN
anesthj-33	216	10	due	due	ADP
anesthj-33	216	11	to	to	ADP
anesthj-33	216	12	a	a	DET
anesthj-33	216	13	mutation	mutation	NOUN
anesthj-33	216	14	in	in	ADP
anesthj-33	216	15	mitochondrial	mitochondrial	ADJ
anesthj-33	216	16	dna	dna	NOUN
anesthj-33	216	17	that	that	PRON
anesthj-33	216	18	causes	cause	VERB
anesthj-33	216	19	a	a	DET
anesthj-33	216	20	disruption	disruption	NOUN
anesthj-33	216	21	in	in	ADP
anesthj-33	216	22	aerobic	aerobic	ADJ
anesthj-33	216	23	metabolism	metabolism	NOUN
anesthj-33	216	24	.	.	PUNCT
anesthj-33	217	1	melas	mela	NOUN
anesthj-33	217	2	has	have	AUX
anesthj-33	217	3	varied	vary	VERB
anesthj-33	217	4	clinical	clinical	ADJ
anesthj-33	217	5	manifestations	manifestation	NOUN
anesthj-33	217	6	including	include	VERB
anesthj-33	217	7	cardiac	cardiac	ADJ
anesthj-33	217	8	,	,	PUNCT
anesthj-33	217	9	neurological	neurological	ADJ
anesthj-33	217	10	,	,	PUNCT
anesthj-33	217	11	and	and	CCONJ
anesthj-33	217	12	muscular	muscular	ADJ
anesthj-33	217	13	.	.	PUNCT
anesthj-33	218	1	patients	patient	NOUN
anesthj-33	218	2	may	may	AUX
anesthj-33	218	3	have	have	VERB
anesthj-33	218	4	varied	varied	ADJ
anesthj-33	218	5	cardiac	cardiac	ADJ
anesthj-33	218	6	disturbances	disturbance	NOUN
anesthj-33	218	7	such	such	ADJ
anesthj-33	218	8	as	as	ADP
anesthj-33	218	9	cardiomyopathy	cardiomyopathy	ADJ
anesthj-33	218	10	,	,	PUNCT
anesthj-33	218	11	may	may	AUX
anesthj-33	218	12	suffer	suffer	VERB
anesthj-33	218	13	from	from	ADP
anesthj-33	218	14	strokes	stroke	NOUN
anesthj-33	218	15	,	,	PUNCT
anesthj-33	218	16	and	and	CCONJ
anesthj-33	218	17	can	can	AUX
anesthj-33	218	18	also	also	ADV
anesthj-33	218	19	have	have	VERB
anesthj-33	218	20	muscle	muscle	NOUN
anesthj-33	218	21	wasting	waste	VERB
anesthj-33	218	22	.	.	PUNCT
anesthj-33	219	1	•	•	NUM
anesthj-33	219	2	the	the	DET
anesthj-33	219	3	malignant	malignant	ADJ
anesthj-33	219	4	hyperthermia	hyperthermia	NOUN
anesthj-33	219	5	association	association	NOUN
anesthj-33	219	6	of	of	ADP
anesthj-33	219	7	the	the	DET
anesthj-33	219	8	united	united	PROPN
anesthj-33	219	9	states	states	PROPN
anesthj-33	219	10	does	do	AUX
anesthj-33	219	11	not	not	PART
anesthj-33	219	12	recommend	recommend	VERB
anesthj-33	219	13	avoiding	avoid	VERB
anesthj-33	219	14	volatile	volatile	ADJ
anesthj-33	219	15	agents	agent	NOUN
anesthj-33	219	16	in	in	ADP
anesthj-33	219	17	mitochondrial	mitochondrial	ADJ
anesthj-33	219	18	myopathy	myopathy	ADJ
anesthj-33	219	19	patients	patient	NOUN
anesthj-33	219	20	even	even	ADV
anesthj-33	219	21	though	though	SCONJ
anesthj-33	219	22	mitochondrial	mitochondrial	ADJ
anesthj-33	219	23	myopathy	myopathy	NOUN
anesthj-33	219	24	has	have	VERB
anesthj-33	219	25	a	a	DET
anesthj-33	219	26	similar	similar	ADJ
anesthj-33	219	27	presentation	presentation	NOUN
anesthj-33	219	28	of	of	ADP
anesthj-33	219	29	symptoms	symptom	NOUN
anesthj-33	219	30	to	to	ADP
anesthj-33	219	31	malignant	malignant	ADJ
anesthj-33	219	32	hyperthermia	hyperthermia	NOUN
anesthj-33	219	33	.	.	PUNCT
anesthj-33	220	1	•	•	NUM
anesthj-33	220	2	the	the	DET
anesthj-33	220	3	safe	safe	ADJ
anesthj-33	220	4	use	use	NOUN
anesthj-33	220	5	of	of	ADP
anesthj-33	220	6	an	an	DET
anesthj-33	220	7	anesthetic	anesthetic	ADJ
anesthj-33	220	8	technique	technique	NOUN
anesthj-33	220	9	in	in	ADP
anesthj-33	220	10	one	one	NUM
anesthj-33	220	11	type	type	NOUN
anesthj-33	220	12	of	of	ADP
anesthj-33	220	13	mitochondrial	mitochondrial	ADJ
anesthj-33	220	14	myopathy	myopathy	NOUN
anesthj-33	220	15	does	do	AUX
anesthj-33	220	16	not	not	PART
anesthj-33	220	17	translate	translate	VERB
anesthj-33	220	18	to	to	ADP
anesthj-33	220	19	safety	safety	NOUN
anesthj-33	220	20	in	in	ADP
anesthj-33	220	21	melas	mela	NOUN
anesthj-33	220	22	.	.	PUNCT
anesthj-33	221	1	however	however	ADV
anesthj-33	221	2	,	,	PUNCT
anesthj-33	221	3	epidural	epidural	ADJ
anesthj-33	221	4	anesthesia	anesthesia	NOUN
anesthj-33	221	5	,	,	PUNCT
anesthj-33	221	6	spinal	spinal	NOUN
anesthj-33	221	7	anesthesia	anesthesia	NOUN
anesthj-33	221	8	,	,	PUNCT
anesthj-33	221	9	and	and	CCONJ
anesthj-33	221	10	general	general	ADJ
anesthj-33	221	11	endotracheal	endotracheal	NOUN
anesthj-33	221	12	anesthesia	anesthesia	PROPN
anesthj-33	221	13	have	have	AUX
anesthj-33	221	14	all	all	PRON
anesthj-33	221	15	been	be	AUX
anesthj-33	221	16	used	use	VERB
anesthj-33	221	17	safely	safely	ADV
anesthj-33	221	18	with	with	ADP
anesthj-33	221	19	various	various	ADJ
anesthj-33	221	20	muscle	muscle	NOUN
anesthj-33	221	21	relaxants	relaxant	NOUN
anesthj-33	221	22	and	and	CCONJ
anesthj-33	221	23	opioids	opioid	NOUN
anesthj-33	221	24	in	in	ADP
anesthj-33	221	25	patients	patient	NOUN
anesthj-33	221	26	with	with	ADP
anesthj-33	221	27	melas	mela	NOUN
anesthj-33	221	28	in	in	ADP
anesthj-33	221	29	multiple	multiple	ADJ
anesthj-33	221	30	case	case	NOUN
anesthj-33	221	31	reports	report	VERB
anesthj-33	221	32	.	.	PUNCT
anesthj-33	222	1	•	•	INTJ
anesthj-33	222	2	it	it	PRON
anesthj-33	222	3	is	be	AUX
anesthj-33	222	4	paramount	paramount	ADJ
anesthj-33	222	5	for	for	SCONJ
anesthj-33	222	6	the	the	DET
anesthj-33	222	7	anesthesia	anesthesia	NOUN
anesthj-33	222	8	provider	provider	NOUN
anesthj-33	222	9	to	to	PART
anesthj-33	222	10	remember	remember	VERB
anesthj-33	222	11	that	that	SCONJ
anesthj-33	222	12	the	the	DET
anesthj-33	222	13	stress	stress	NOUN
anesthj-33	222	14	of	of	ADP
anesthj-33	222	15	surgery	surgery	NOUN
anesthj-33	222	16	and	and	CCONJ
anesthj-33	222	17	anesthesia	anesthesia	PROPN
anesthj-33	222	18	itself	itself	PRON
anesthj-33	222	19	can	can	AUX
anesthj-33	222	20	increase	increase	VERB
anesthj-33	222	21	metabolic	metabolic	ADJ
anesthj-33	222	22	demand	demand	NOUN
anesthj-33	222	23	in	in	ADP
anesthj-33	222	24	these	these	DET
anesthj-33	222	25	patients	patient	NOUN
anesthj-33	222	26	who	who	PRON
anesthj-33	222	27	are	be	AUX
anesthj-33	222	28	unable	unable	ADJ
anesthj-33	222	29	to	to	PART
anesthj-33	222	30	meet	meet	VERB
anesthj-33	222	31	the	the	DET
anesthj-33	222	32	necessary	necessary	ADJ
anesthj-33	222	33	energy	energy	NOUN
anesthj-33	222	34	requirements	requirement	NOUN
anesthj-33	222	35	.	.	PUNCT
anesthj-33	223	1	therefore	therefore	ADV
anesthj-33	223	2	,	,	PUNCT
anesthj-33	223	3	a	a	DET
anesthj-33	223	4	cardiovascularly	cardiovascularly	PROPN
anesthj-33	223	5	stable	stable	ADJ
anesthj-33	223	6	anesthetic	anesthetic	NOUN
anesthj-33	223	7	is	be	AUX
anesthj-33	223	8	appropriate	appropriate	ADJ
anesthj-33	223	9	.	.	PUNCT
anesthj-33	224	1	•	•	NUM
anesthj-33	224	2	avoidance	avoidance	NOUN
anesthj-33	224	3	of	of	ADP
anesthj-33	224	4	hypothermia	hypothermia	NOUN
anesthj-33	224	5	,	,	PUNCT
anesthj-33	224	6	postoperative	postoperative	ADJ
anesthj-33	224	7	nausea	nausea	NOUN
anesthj-33	224	8	vomiting	vomiting	NOUN
anesthj-33	224	9	,	,	PUNCT
anesthj-33	224	10	and	and	CCONJ
anesthj-33	224	11	lactate	lactate	NOUN
anesthj-33	224	12	in	in	ADP
anesthj-33	224	13	intravenous	intravenous	ADJ
anesthj-33	224	14	fluids	fluid	NOUN
anesthj-33	224	15	are	be	AUX
anesthj-33	224	16	mandatory	mandatory	ADJ
anesthj-33	224	17	interventions	intervention	NOUN
anesthj-33	224	18	in	in	ADP
anesthj-33	224	19	melas	mela	NOUN
anesthj-33	224	20	patients	patient	NOUN
anesthj-33	224	21	.	.	PUNCT
anesthj-33	225	1	•	•	NUM
anesthj-33	225	2	careful	careful	ADJ
anesthj-33	225	3	titration	titration	NOUN
anesthj-33	225	4	of	of	ADP
anesthj-33	225	5	muscle	muscle	NOUN
anesthj-33	225	6	relaxants	relaxant	NOUN
anesthj-33	225	7	,	,	PUNCT
anesthj-33	225	8	opioids	opioid	NOUN
anesthj-33	225	9	,	,	PUNCT
anesthj-33	225	10	and	and	CCONJ
anesthj-33	225	11	other	other	ADJ
anesthj-33	225	12	intravenous	intravenous	ADJ
anesthj-33	225	13	anesthetics	anesthetic	NOUN
anesthj-33	225	14	is	be	AUX
anesthj-33	225	15	necessary	necessary	ADJ
anesthj-33	225	16	because	because	SCONJ
anesthj-33	225	17	these	these	DET
anesthj-33	225	18	patients	patient	NOUN
anesthj-33	225	19	are	be	AUX
anesthj-33	225	20	at	at	ADP
anesthj-33	225	21	risk	risk	NOUN
anesthj-33	225	22	for	for	ADP
anesthj-33	225	23	postoperative	postoperative	ADJ
anesthj-33	225	24	respiratory	respiratory	ADJ
anesthj-33	225	25	failure	failure	NOUN
anesthj-33	225	26	.	.	PUNCT
anesthj-33	226	1	anesthesia	anesthesia	PROPN
anesthj-33	226	2	ejournal	ejournal	PROPN
anesthj-33	226	3	www.anesthesiaejournal.com	www.anesthesiaejournal.com	PROPN
anesthj-33	226	4	volume	volume	NOUN
anesthj-33	226	5	4	4	NUM
anesthj-33	226	6	issue	issue	NOUN
anesthj-33	226	7	1	1	NUM
anesthj-33	226	8	2016	2016	NUM
anesthj-33	226	9	page	page	NOUN
anesthj-33	226	10	25	25	NUM
