id	sid	tid	token	lemma	pos
app-795	1	1	48	48	NUM
app-795	1	2	annals	annal	NOUN
app-795	1	3	of	of	ADP
app-795	1	4	applied	apply	VERB
app-795	1	5	psychophysiology	psychophysiology	NOUN
app-795	1	6	december	december	PROPN
app-795	1	7	2025	2025	NUM
app-795	1	8	volume	volume	NOUN
app-795	1	9	13	13	NUM
app-795	1	10	_	_	PUNCT
app-795	2	1	_	_	PUNCT
app-795	3	1	_	_	PUNCT
app-795	4	1	_	_	PUNCT
app-795	5	1	_	_	PUNCT
app-795	6	1	_	_	PUNCT
app-795	7	1	_	_	PUNCT
app-795	8	1	_	_	PUNCT
app-795	9	1	_	_	PUNCT
app-795	10	1	_	_	PUNCT
app-795	11	1	_	_	PUNCT
app-795	12	1	_	_	PUNCT
app-795	13	1	_	_	PUNCT
app-795	14	1	_	_	PUNCT
app-795	15	1	_	_	PUNCT
app-795	16	1	_	_	PUNCT
app-795	17	1	_	_	PUNCT
app-795	18	1	_	_	PUNCT
app-795	19	1	_	_	PUNCT
app-795	20	1	_	_	PUNCT
app-795	21	1	_	_	PUNCT
app-795	22	1	_	_	PUNCT
app-795	23	1	_	_	PUNCT
app-795	24	1	_	_	PUNCT
app-795	25	1	_	_	PUNCT
app-795	26	1	_	_	PUNCT
app-795	27	1	_	_	PUNCT
app-795	28	1	_	_	PUNCT
app-795	29	1	_	_	PUNCT
app-795	30	1	_	_	PUNCT
app-795	31	1	_	_	PUNCT
app-795	32	1	_	_	PUNCT
app-795	33	1	_	_	PUNCT
app-795	34	1	_	_	PUNCT
app-795	35	1	_	_	PUNCT
app-795	36	1	_	_	PUNCT
app-795	37	1	_	_	PUNCT
app-795	38	1	_	_	PUNCT
app-795	39	1	_	_	PUNCT
app-795	40	1	_	_	PUNCT
app-795	41	1	_	_	PUNCT
app-795	42	1	_	_	PUNCT
app-795	43	1	_	_	PUNCT
app-795	44	1	_	_	PUNCT
app-795	45	1	_	_	PUNCT
app-795	46	1	_	_	PUNCT
app-795	47	1	_	_	PUNCT
app-795	48	1	_	_	PUNCT
app-795	49	1	_	_	PUNCT
app-795	50	1	_	_	PUNCT
app-795	51	1	_	_	PUNCT
app-795	52	1	_	_	PUNCT
app-795	53	1	_	_	PUNCT
app-795	54	1	_	_	PUNCT
app-795	55	1	_	_	PUNCT
app-795	56	1	_	_	PUNCT
app-795	57	1	_	_	PUNCT
app-795	58	1	_	_	PUNCT
app-795	59	1	_	_	PUNCT
app-795	60	1	_	_	PUNCT
app-795	61	1	_	_	PUNCT
app-795	62	1	_	_	PUNCT
app-795	63	1	_	_	PUNCT
app-795	64	1	_	_	PUNCT
app-795	65	1	_	_	PUNCT
app-795	66	1	_	_	PUNCT
app-795	67	1	_	_	PUNCT
app-795	68	1	_	_	PUNCT
app-795	68	2	_	_	PUNCT
app-795	69	1	the	the	DET
app-795	69	2	triad	triad	NOUN
app-795	69	3	of	of	ADP
app-795	69	4	stress	stress	NOUN
app-795	69	5	,	,	PUNCT
app-795	69	6	vitamin	vitamin	NOUN
app-795	69	7	d	d	NOUN
app-795	69	8	deficiency	deficiency	NOUN
app-795	69	9	,	,	PUNCT
app-795	69	10	and	and	CCONJ
app-795	69	11	periodontal	periodontal	ADJ
app-795	69	12	breakdown	breakdown	NOUN
app-795	69	13	:	:	PUNCT
app-795	69	14	an	an	DET
app-795	69	15	integrative	integrative	ADJ
app-795	69	16	review	review	NOUN
app-795	69	17	rafique	rafique	PROPN
app-795	69	18	s	s	PROPN
app-795	69	19	,	,	PUNCT
app-795	69	20	ahmed	ahmed	PROPN
app-795	69	21	s	s	PROPN
app-795	69	22	,	,	PUNCT
app-795	69	23	noushad	noushad	VERB
app-795	69	24	s	s	PART
app-795	69	25	,	,	PUNCT
app-795	69	26	atif	atif	PROPN
app-795	69	27	a	a	X
app-795	69	28	,	,	PUNCT
app-795	69	29	aqeel	aqeel	PROPN
app-795	69	30	s	s	PROPN
app-795	69	31	,	,	PUNCT
app-795	69	32	nasir	nasir	PROPN
app-795	69	33	f	f	PROPN
app-795	69	34	published	publish	VERB
app-795	69	35	online	online	ADV
app-795	69	36	:	:	PUNCT
app-795	69	37	december	december	PROPN
app-795	69	38	2025	2025	NUM
app-795	70	1	©	©	ADP
app-795	70	2	the	the	DET
app-795	70	3	author(s	author(s	NOUN
app-795	70	4	)	)	PUNCT
app-795	70	5	abstract	abstract	ADJ
app-795	70	6	background	background	NOUN
app-795	70	7	:	:	PUNCT
app-795	70	8	recent	recent	ADJ
app-795	70	9	studies	study	NOUN
app-795	70	10	have	have	AUX
app-795	70	11	highlighted	highlight	VERB
app-795	70	12	a	a	DET
app-795	70	13	significant	significant	ADJ
app-795	70	14	link	link	NOUN
app-795	70	15	between	between	ADP
app-795	70	16	psychological	psychological	ADJ
app-795	70	17	disorders	disorder	NOUN
app-795	70	18	and	and	CCONJ
app-795	70	19	oral	oral	ADJ
app-795	70	20	inflammatory	inflammatory	ADJ
app-795	70	21	diseases	disease	NOUN
app-795	70	22	.	.	PUNCT
app-795	71	1	emotional	emotional	ADJ
app-795	71	2	disorders	disorder	NOUN
app-795	71	3	such	such	ADJ
app-795	71	4	as	as	ADP
app-795	71	5	anxiety	anxiety	NOUN
app-795	71	6	and	and	CCONJ
app-795	71	7	depression	depression	NOUN
app-795	71	8	can	can	AUX
app-795	71	9	interfere	interfere	VERB
app-795	71	10	with	with	ADP
app-795	71	11	normal	normal	ADJ
app-795	71	12	body	body	NOUN
app-795	71	13	functions	function	NOUN
app-795	71	14	by	by	ADP
app-795	71	15	disturbing	disturb	VERB
app-795	71	16	the	the	DET
app-795	71	17	neuro	neuro	NOUN
app-795	71	18	-	-	PUNCT
app-795	71	19	immune	immune	ADJ
app-795	71	20	-	-	PUNCT
app-795	71	21	endocrine	endocrine	NOUN
app-795	71	22	axis	axis	NOUN
app-795	71	23	.	.	PUNCT
app-795	72	1	methodology	methodology	NOUN
app-795	72	2	:	:	PUNCT
app-795	72	3	this	this	DET
app-795	72	4	mini	mini	ADJ
app-795	72	5	-	-	NOUN
app-795	72	6	review	review	NOUN
app-795	72	7	highlights	highlight	NOUN
app-795	72	8	the	the	DET
app-795	72	9	importance	importance	NOUN
app-795	72	10	of	of	ADP
app-795	72	11	integrated	integrated	ADJ
app-795	72	12	approaches	approach	NOUN
app-795	72	13	in	in	ADP
app-795	72	14	dental	dental	ADJ
app-795	72	15	and	and	CCONJ
app-795	72	16	mental	mental	ADJ
app-795	72	17	health	health	NOUN
app-795	72	18	care	care	NOUN
app-795	72	19	by	by	ADP
app-795	72	20	integrating	integrate	VERB
app-795	72	21	research	research	NOUN
app-795	72	22	that	that	PRON
app-795	72	23	links	link	VERB
app-795	72	24	oral	oral	ADJ
app-795	72	25	and	and	CCONJ
app-795	72	26	psychological	psychological	ADJ
app-795	72	27	domains	domain	NOUN
app-795	72	28	.	.	PUNCT
app-795	73	1	results	result	NOUN
app-795	73	2	:	:	PUNCT
app-795	73	3	these	these	DET
app-795	73	4	alterations	alteration	NOUN
app-795	73	5	trigger	trigger	VERB
app-795	73	6	the	the	DET
app-795	73	7	onset	onset	NOUN
app-795	73	8	and	and	CCONJ
app-795	73	9	progression	progression	NOUN
app-795	73	10	of	of	ADP
app-795	73	11	periodontitis	periodontitis	NOUN
app-795	73	12	,	,	PUNCT
app-795	73	13	a	a	DET
app-795	73	14	chronic	chronic	ADJ
app-795	73	15	inflammatory	inflammatory	ADJ
app-795	73	16	disease	disease	NOUN
app-795	73	17	that	that	PRON
app-795	73	18	harms	harm	VERB
app-795	73	19	the	the	DET
app-795	73	20	tissues	tissue	NOUN
app-795	73	21	supporting	support	VERB
app-795	73	22	the	the	DET
app-795	73	23	teeth	tooth	NOUN
app-795	73	24	.	.	PUNCT
app-795	74	1	vitamin	vitamin	NOUN
app-795	74	2	d	d	NOUN
app-795	74	3	,	,	PUNCT
app-795	74	4	especially	especially	ADV
app-795	74	5	its	its	PRON
app-795	74	6	active	active	ADJ
app-795	74	7	form	form	NOUN
app-795	74	8	,	,	PUNCT
app-795	74	9	1,25	1,25	NUM
app-795	74	10	-	-	PUNCT
app-795	74	11	dihydroxyvitamin	dihydroxyvitamin	ADJ
app-795	74	12	d₃	d₃	PROPN
app-795	74	13	,	,	PUNCT
app-795	74	14	has	have	AUX
app-795	74	15	recently	recently	ADV
app-795	74	16	been	be	AUX
app-795	74	17	considered	consider	VERB
app-795	74	18	as	as	ADP
app-795	74	19	a	a	DET
app-795	74	20	vital	vital	ADJ
app-795	74	21	hormone	hormone	NOUN
app-795	74	22	in	in	ADP
app-795	74	23	protecting	protect	VERB
app-795	74	24	mental	mental	ADJ
app-795	74	25	and	and	CCONJ
app-795	74	26	periodontal	periodontal	ADJ
app-795	74	27	health	health	NOUN
app-795	74	28	.	.	PUNCT
app-795	75	1	conclusion	conclusion	NOUN
app-795	75	2	:	:	PUNCT
app-795	75	3	saliva	saliva	NOUN
app-795	75	4	provides	provide	VERB
app-795	75	5	a	a	DET
app-795	75	6	noninvasive	noninvasive	ADJ
app-795	75	7	means	mean	NOUN
app-795	75	8	for	for	ADP
app-795	75	9	assessing	assess	VERB
app-795	75	10	physiological	physiological	ADJ
app-795	75	11	markers	marker	NOUN
app-795	75	12	such	such	ADJ
app-795	75	13	as	as	ADP
app-795	75	14	alpha	alpha	NOUN
app-795	75	15	-	-	PUNCT
app-795	75	16	amylase	amylase	NOUN
app-795	75	17	(	(	PUNCT
app-795	75	18	saa	saa	PROPN
app-795	75	19	)	)	PUNCT
app-795	75	20	,	,	PUNCT
app-795	75	21	cortisol	cortisol	NOUN
app-795	75	22	,	,	PUNCT
app-795	75	23	interleukin-6	interleukin-6	PROPN
app-795	75	24	(	(	PUNCT
app-795	75	25	il-6	il-6	NUM
app-795	75	26	)	)	PUNCT
app-795	75	27	,	,	PUNCT
app-795	75	28	and	and	CCONJ
app-795	75	29	chromogranin	chromogranin	VERB
app-795	75	30	-	-	PUNCT
app-795	75	31	a	a	DET
app-795	75	32	(	(	PUNCT
app-795	75	33	cg	cg	NOUN
app-795	75	34	-	-	PUNCT
app-795	75	35	a	a	NOUN
app-795	75	36	)	)	PUNCT
app-795	75	37	.	.	PUNCT
app-795	76	1	these	these	DET
app-795	76	2	biomarkers	biomarker	NOUN
app-795	76	3	can	can	AUX
app-795	76	4	offer	offer	VERB
app-795	76	5	insight	insight	NOUN
app-795	76	6	into	into	ADP
app-795	76	7	bodily	bodily	ADJ
app-795	76	8	changes	change	NOUN
app-795	76	9	associated	associate	VERB
app-795	76	10	with	with	ADP
app-795	76	11	oral	oral	ADJ
app-795	76	12	inflammation	inflammation	NOUN
app-795	76	13	and	and	CCONJ
app-795	76	14	psychological	psychological	ADJ
app-795	76	15	stress	stress	NOUN
app-795	76	16	.	.	PUNCT
app-795	77	1	keywords	keyword	NOUN
app-795	77	2	:	:	PUNCT
app-795	77	3	monosodium	monosodium	NOUN
app-795	77	4	glutamate	glutamate	NOUN
app-795	77	5	(	(	PUNCT
app-795	77	6	msg	msg	PROPN
app-795	77	7	)	)	PUNCT
app-795	77	8	,	,	PUNCT
app-795	77	9	dietary	dietary	ADJ
app-795	77	10	glutamate	glutamate	NOUN
app-795	77	11	,	,	PUNCT
app-795	77	12	depressive	depressive	ADJ
app-795	77	13	-	-	PUNCT
app-795	77	14	like	like	ADJ
app-795	77	15	phenotypes	phenotype	NOUN
app-795	77	16	,	,	PUNCT
app-795	77	17	monosodium	monosodium	NOUN
app-795	77	18	glutamate	glutamate	NOUN
app-795	77	19	induced	induce	VERB
app-795	77	20	depression	depression	NOUN
app-795	77	21	,	,	PUNCT
app-795	77	22	neurotoxicity	neurotoxicity	NOUN
app-795	77	23	,	,	PUNCT
app-795	77	24	animal	animal	NOUN
app-795	77	25	models	model	NOUN
app-795	77	26	,	,	PUNCT
app-795	77	27	supraphysiological	supraphysiological	ADJ
app-795	77	28	doses	dose	NOUN
app-795	77	29	.	.	PUNCT
app-795	78	1	corresponding	correspond	VERB
app-795	78	2	author	author	PROPN
app-795	78	3	dr	dr	PROPN
app-795	78	4	.	.	PROPN
app-795	78	5	sara	sara	PROPN
app-795	78	6	rafique	rafique	PROPN
app-795	78	7	,	,	PUNCT
app-795	78	8	mphil	mphil	PROPN
app-795	78	9	,	,	PUNCT
app-795	78	10	phd	phd	NOUN
app-795	78	11	scholar	scholar	NOUN
app-795	78	12	associate	associate	NOUN
app-795	78	13	professor	professor	NOUN
app-795	78	14	,	,	PUNCT
app-795	78	15	department	department	NOUN
app-795	78	16	of	of	ADP
app-795	78	17	physiology	physiology	NOUN
app-795	78	18	,	,	PUNCT
app-795	78	19	jinnah	jinnah	PROPN
app-795	78	20	medical	medical	PROPN
app-795	78	21	&	&	CCONJ
app-795	78	22	dental	dental	PROPN
app-795	78	23	college	college	PROPN
app-795	78	24	,	,	PUNCT
app-795	78	25	sohail	sohail	PROPN
app-795	78	26	university	university	PROPN
app-795	78	27	,	,	PUNCT
app-795	78	28	shaheed	shaheed	NOUN
app-795	78	29	-	-	PUNCT
app-795	78	30	e	e	NOUN
app-795	78	31	-	-	ADJ
app-795	78	32	millat	millat	ADJ
app-795	78	33	road	road	NOUN
app-795	78	34	,	,	PUNCT
app-795	78	35	karachi	karachi	PROPN
app-795	78	36	,	,	PUNCT
app-795	78	37	pakistan	pakistan	PROPN
app-795	78	38	ph	ph	PROPN
app-795	78	39	:	:	PUNCT
app-795	78	40	93345386644	93345386644	NUM
app-795	78	41	e	e	X
app-795	78	42	mail	mail	NOUN
app-795	78	43	:	:	PUNCT
app-795	78	44	sararafique@jmc.edu.pk	sararafique@jmc.edu.pk	ADJ
app-795	78	45	introduction	introduction	NOUN
app-795	78	46	the	the	DET
app-795	78	47	link	link	NOUN
app-795	78	48	between	between	ADP
app-795	78	49	mental	mental	ADJ
app-795	78	50	health	health	NOUN
app-795	78	51	and	and	CCONJ
app-795	78	52	systemic	systemic	ADJ
app-795	78	53	inflammatory	inflammatory	ADJ
app-795	78	54	diseases	disease	NOUN
app-795	78	55	has	have	AUX
app-795	78	56	gained	gain	VERB
app-795	78	57	significant	significant	ADJ
app-795	78	58	attention	attention	NOUN
app-795	78	59	,	,	PUNCT
app-795	78	60	as	as	SCONJ
app-795	78	61	the	the	DET
app-795	78	62	prevalence	prevalence	NOUN
app-795	78	63	of	of	ADP
app-795	78	64	anxiety	anxiety	NOUN
app-795	78	65	and	and	CCONJ
app-795	78	66	depression	depression	NOUN
app-795	78	67	is	be	AUX
app-795	78	68	increasing	increase	VERB
app-795	78	69	worldwide	worldwide	ADV
app-795	79	1	[	[	X
app-795	79	2	1	1	NUM
app-795	79	3	]	]	PUNCT
app-795	79	4	.	.	PUNCT
app-795	80	1	mental	mental	ADJ
app-795	80	2	health	health	NOUN
app-795	80	3	disorders	disorder	NOUN
app-795	80	4	are	be	AUX
app-795	80	5	increasingly	increasingly	ADV
app-795	80	6	recognized	recognize	VERB
app-795	80	7	not	not	PART
app-795	80	8	merely	merely	ADV
app-795	80	9	as	as	ADP
app-795	80	10	cognitive	cognitive	ADJ
app-795	80	11	or	or	CCONJ
app-795	80	12	emotional	emotional	ADJ
app-795	80	13	disorders	disorder	NOUN
app-795	80	14	,	,	PUNCT
app-795	80	15	but	but	CCONJ
app-795	80	16	as	as	ADP
app-795	80	17	conditions	condition	NOUN
app-795	80	18	affecting	affect	VERB
app-795	80	19	the	the	DET
app-795	80	20	oral	oral	ADJ
app-795	80	21	health	health	NOUN
app-795	80	22	domain	domain	NOUN
app-795	80	23	.	.	PUNCT
app-795	81	1	the	the	DET
app-795	81	2	detrimental	detrimental	ADJ
app-795	81	3	effects	effect	NOUN
app-795	81	4	on	on	ADP
app-795	81	5	periodontal	periodontal	ADJ
app-795	81	6	tissues	tissue	NOUN
app-795	81	7	have	have	AUX
app-795	81	8	become	become	VERB
app-795	81	9	a	a	DET
app-795	81	10	focus	focus	NOUN
app-795	81	11	of	of	ADP
app-795	81	12	growing	grow	VERB
app-795	81	13	attention	attention	NOUN
app-795	81	14	[	[	X
app-795	81	15	2	2	NUM
app-795	81	16	,	,	PUNCT
app-795	81	17	3	3	NUM
app-795	81	18	]	]	PUNCT
app-795	81	19	.	.	PUNCT
app-795	82	1	periodontitis	periodontitis	NOUN
app-795	82	2	is	be	AUX
app-795	82	3	an	an	DET
app-795	82	4	ongoing	ongoing	ADJ
app-795	82	5	inflammatory	inflammatory	ADJ
app-795	82	6	infection	infection	NOUN
app-795	82	7	affecting	affect	VERB
app-795	82	8	the	the	DET
app-795	82	9	supporting	support	VERB
app-795	82	10	structures	structure	NOUN
app-795	82	11	of	of	ADP
app-795	82	12	the	the	DET
app-795	82	13	teeth	tooth	NOUN
app-795	83	1	[	[	X
app-795	83	2	3	3	NUM
app-795	83	3	]	]	PUNCT
app-795	83	4	.	.	PUNCT
app-795	84	1	the	the	DET
app-795	84	2	body	body	NOUN
app-795	84	3	's	's	PART
app-795	84	4	stress	stress	NOUN
app-795	84	5	response	response	NOUN
app-795	84	6	serves	serve	VERB
app-795	84	7	as	as	ADP
app-795	84	8	an	an	DET
app-795	84	9	amalgamating	amalgamate	VERB
app-795	84	10	link	link	NOUN
app-795	84	11	between	between	ADP
app-795	84	12	oral	oral	ADJ
app-795	84	13	and	and	CCONJ
app-795	84	14	mental	mental	ADJ
app-795	84	15	health	health	NOUN
app-795	84	16	.	.	PUNCT
app-795	85	1	chronic	chronic	ADJ
app-795	85	2	stress	stress	NOUN
app-795	85	3	can	can	AUX
app-795	85	4	lead	lead	VERB
app-795	85	5	to	to	ADP
app-795	85	6	the	the	DET
app-795	85	7	over	over	NOUN
app-795	85	8	-	-	PUNCT
app-795	85	9	stimulation	stimulation	NOUN
app-795	85	10	of	of	ADP
app-795	85	11	the	the	DET
app-795	85	12	hypothalamic	hypothalamic	ADJ
app-795	85	13	-	-	PUNCT
app-795	85	14	pituitary	pituitary	ADJ
app-795	85	15	-	-	PUNCT
app-795	85	16	adrenal	adrenal	ADJ
app-795	85	17	(	(	PUNCT
app-795	85	18	hpa	hpa	NOUN
app-795	85	19	)	)	PUNCT
app-795	85	20	axis	axis	NOUN
app-795	85	21	and	and	CCONJ
app-795	85	22	the	the	DET
app-795	85	23	sympathetic	sympathetic	ADJ
app-795	85	24	nervous	nervous	ADJ
app-795	85	25	system	system	NOUN
app-795	85	26	(	(	PUNCT
app-795	85	27	sns).this	sns).this	DET
app-795	85	28	results	result	NOUN
app-795	85	29	in	in	ADP
app-795	85	30	elevated	elevated	ADJ
app-795	85	31	cortisol	cortisol	ADJ
app-795	85	32	levels	level	NOUN
app-795	85	33	.	.	PUNCT
app-795	86	1	the	the	DET
app-795	86	2	continuously	continuously	ADV
app-795	86	3	raised	raise	VERB
app-795	86	4	cortisol	cortisol	ADJ
app-795	86	5	levels	level	NOUN
app-795	86	6	can	can	AUX
app-795	86	7	disrupt	disrupt	VERB
app-795	86	8	the	the	DET
app-795	86	9	balance	balance	NOUN
app-795	86	10	of	of	ADP
app-795	86	11	the	the	DET
app-795	86	12	immune	immune	ADJ
app-795	86	13	response	response	NOUN
app-795	86	14	,	,	PUNCT
app-795	86	15	shifting	shift	VERB
app-795	86	16	it	it	PRON
app-795	86	17	towards	towards	ADP
app-795	86	18	a	a	DET
app-795	86	19	more	more	ADV
app-795	86	20	destructive	destructive	ADJ
app-795	86	21	inflammatory	inflammatory	ADJ
app-795	86	22	state	state	NOUN
app-795	86	23	.	.	PUNCT
app-795	87	1	this	this	DET
app-795	87	2	inflammatory	inflammatory	ADJ
app-795	87	3	state	state	NOUN
app-795	87	4	contributes	contribute	VERB
app-795	87	5	to	to	ADP
app-795	87	6	systemic	systemic	ADJ
app-795	87	7	and	and	CCONJ
app-795	87	8	oral	oral	ADJ
app-795	87	9	health	health	NOUN
app-795	87	10	issues	issue	NOUN
app-795	87	11	[	[	X
app-795	87	12	4	4	NUM
app-795	87	13	]	]	PUNCT
app-795	87	14	.	.	PUNCT
app-795	88	1	vitamin	vitamin	NOUN
app-795	88	2	d	d	PROPN
app-795	88	3	,	,	PUNCT
app-795	88	4	a	a	DET
app-795	88	5	steroid	steroid	NOUN
app-795	88	6	hormone	hormone	NOUN
app-795	88	7	,	,	PUNCT
app-795	88	8	is	be	AUX
app-795	88	9	not	not	PART
app-795	88	10	only	only	ADV
app-795	88	11	a	a	DET
app-795	88	12	bone	bone	NOUN
app-795	88	13	-	-	PUNCT
app-795	88	14	regulating	regulate	VERB
app-795	88	15	vitamin	vitamin	NOUN
app-795	88	16	,	,	PUNCT
app-795	88	17	but	but	CCONJ
app-795	88	18	is	be	AUX
app-795	88	19	also	also	ADV
app-795	88	20	involved	involve	VERB
app-795	88	21	in	in	ADP
app-795	88	22	the	the	DET
app-795	88	23	regulation	regulation	NOUN
app-795	88	24	of	of	ADP
app-795	88	25	mood	mood	NOUN
app-795	88	26	.	.	PUNCT
app-795	89	1	deficiency	deficiency	NOUN
app-795	89	2	in	in	ADP
app-795	89	3	vitamin	vitamin	NOUN
app-795	89	4	d	d	NOUN
app-795	89	5	has	have	AUX
app-795	89	6	been	be	AUX
app-795	89	7	linked	link	VERB
app-795	89	8	to	to	ADP
app-795	89	9	a	a	DET
app-795	89	10	higher	high	ADJ
app-795	89	11	risk	risk	NOUN
app-795	89	12	of	of	ADP
app-795	89	13	oral	oral	ADJ
app-795	89	14	inflammatory	inflammatory	ADJ
app-795	89	15	diseases	disease	NOUN
app-795	89	16	,	,	PUNCT
app-795	89	17	such	such	ADJ
app-795	89	18	as	as	ADP
app-795	89	19	periodontitis	periodontitis	NOUN
app-795	89	20	[	[	X
app-795	89	21	5	5	NUM
app-795	89	22	,	,	PUNCT
app-795	89	23	6	6	NUM
app-795	89	24	]	]	PUNCT
app-795	89	25	.	.	PUNCT
app-795	90	1	this	this	DET
app-795	90	2	study	study	NOUN
app-795	90	3	examines	examine	VERB
app-795	90	4	the	the	DET
app-795	90	5	pathophysiology	pathophysiology	NOUN
app-795	90	6	of	of	ADP
app-795	90	7	vitamin	vitamin	NOUN
app-795	90	8	d	d	PROPN
app-795	90	9	together	together	ADV
app-795	90	10	with	with	ADP
app-795	90	11	other	other	ADJ
app-795	90	12	stress	stress	NOUN
app-795	90	13	-	-	PUNCT
app-795	90	14	associated	associate	VERB
app-795	90	15	salivary	salivary	ADJ
app-795	90	16	markers	marker	NOUN
app-795	90	17	to	to	PART
app-795	90	18	further	far	ADV
app-795	90	19	clarify	clarify	VERB
app-795	90	20	how	how	SCONJ
app-795	90	21	these	these	DET
app-795	90	22	biomarkers	biomarker	NOUN
app-795	90	23	,	,	PUNCT
app-795	90	24	via	via	ADP
app-795	90	25	interconnected	interconnected	ADJ
app-795	90	26	pathways	pathway	NOUN
app-795	90	27	,	,	PUNCT
app-795	90	28	affect	affect	VERB
app-795	90	29	both	both	DET
app-795	90	30	oral	oral	ADJ
app-795	90	31	health	health	NOUN
app-795	90	32	and	and	CCONJ
app-795	90	33	emotional	emotional	ADJ
app-795	90	34	well	well	ADV
app-795	90	35	-	-	PUNCT
app-795	90	36	being	being	NOUN
app-795	90	37	.	.	PUNCT
app-795	91	1	anxiety	anxiety	NOUN
app-795	91	2	and	and	CCONJ
app-795	91	3	depression	depression	NOUN
app-795	91	4	:	:	PUNCT
app-795	91	5	biological	biological	ADJ
app-795	91	6	mechanisms	mechanism	NOUN
app-795	91	7	related	relate	VERB
app-795	91	8	to	to	ADP
app-795	91	9	oral	oral	ADJ
app-795	91	10	health	health	NOUN
app-795	91	11	anxiety	anxiety	NOUN
app-795	91	12	and	and	CCONJ
app-795	91	13	depression	depression	NOUN
app-795	91	14	arise	arise	VERB
app-795	91	15	from	from	ADP
app-795	91	16	a	a	DET
app-795	91	17	combination	combination	NOUN
app-795	91	18	of	of	ADP
app-795	91	19	physiological	physiological	ADJ
app-795	91	20	,	,	PUNCT
app-795	91	21	psychological	psychological	ADJ
app-795	91	22	,	,	PUNCT
app-795	91	23	and	and	CCONJ
app-795	91	24	environmental	environmental	ADJ
app-795	91	25	factors	factor	NOUN
app-795	91	26	.	.	PUNCT
app-795	92	1	each	each	PRON
app-795	92	2	of	of	ADP
app-795	92	3	these	these	DET
app-795	92	4	factors	factor	NOUN
app-795	92	5	can	can	AUX
app-795	92	6	contribute	contribute	VERB
app-795	92	7	to	to	ADP
app-795	92	8	ongoing	ongoing	ADJ
app-795	92	9	stress	stress	NOUN
app-795	92	10	,	,	PUNCT
app-795	92	11	which	which	PRON
app-795	92	12	in	in	ADP
app-795	92	13	turn	turn	NOUN
app-795	92	14	overactivates	overactivate	VERB
app-795	92	15	the	the	DET
app-795	92	16	hypothalamic	hypothalamic	ADJ
app-795	92	17	-	-	PUNCT
app-795	92	18	pituitary	pituitary	ADJ
app-795	92	19	-	-	PUNCT
app-795	92	20	adrenal	adrenal	ADJ
app-795	92	21	(	(	PUNCT
app-795	92	22	hpa	hpa	NOUN
app-795	92	23	)	)	PUNCT
app-795	92	24	axis	axis	NOUN
app-795	92	25	.	.	PUNCT
app-795	93	1	the	the	DET
app-795	93	2	hpa	hpa	NOUN
app-795	93	3	axis	axis	NOUN
app-795	93	4	normally	normally	ADV
app-795	93	5	maintains	maintain	VERB
app-795	93	6	physiological	physiological	ADJ
app-795	93	7	homeostasis	homeostasis	NOUN
app-795	93	8	during	during	ADP
app-795	93	9	stress	stress	NOUN
app-795	93	10	.	.	PUNCT
app-795	94	1	however	however	ADV
app-795	94	2	,	,	PUNCT
app-795	94	3	when	when	SCONJ
app-795	94	4	its	its	PRON
app-795	94	5	activation	activation	NOUN
app-795	94	6	is	be	AUX
app-795	94	7	prolonged	prolong	VERB
app-795	94	8	,	,	PUNCT
app-795	94	9	cortisol	cortisol	ADJ
app-795	94	10	secretion	secretion	NOUN
app-795	94	11	remains	remain	VERB
app-795	94	12	elevated	elevated	ADJ
app-795	94	13	.	.	PUNCT
app-795	95	1	while	while	SCONJ
app-795	95	2	short	short	ADJ
app-795	95	3	-	-	PUNCT
app-795	95	4	term	term	NOUN
app-795	95	5	cortisol	cortisol	ADJ
app-795	95	6	elevation	elevation	NOUN
app-795	95	7	shifts	shift	NOUN
app-795	95	8	the	the	DET
app-795	95	9	immune	immune	ADJ
app-795	95	10	system	system	NOUN
app-795	95	11	towards	towards	ADP
app-795	95	12	an	an	DET
app-795	95	13	anti	anti	ADJ
app-795	95	14	-	-	ADJ
app-795	95	15	inflammatory	inflammatory	ADJ
app-795	95	16	state	state	NOUN
app-795	95	17	,	,	PUNCT
app-795	95	18	its	its	PRON
app-795	95	19	chronically	chronically	ADV
app-795	95	20	heightened	heighten	VERB
app-795	95	21	levels	level	NOUN
app-795	95	22	can	can	AUX
app-795	95	23	suppress	suppress	VERB
app-795	95	24	immune	immune	ADJ
app-795	95	25	responses	response	NOUN
app-795	95	26	and	and	CCONJ
app-795	95	27	promote	promote	VERB
app-795	95	28	both	both	CCONJ
app-795	95	29	systemic	systemic	ADJ
app-795	95	30	and	and	CCONJ
app-795	95	31	neural	neural	ADJ
app-795	95	32	inflammation	inflammation	NOUN
app-795	95	33	[	[	X
app-795	95	34	3	3	NUM
app-795	95	35	,	,	PUNCT
app-795	95	36	7	7	NUM
app-795	95	37	]	]	PUNCT
app-795	95	38	.	.	PUNCT
app-795	96	1	neuroinflammation	neuroinflammation	NOUN
app-795	96	2	-	-	PUNCT
app-795	96	3	induced	induce	VERB
app-795	96	4	alterations	alteration	NOUN
app-795	96	5	in	in	ADP
app-795	96	6	cortisol	cortisol	ADJ
app-795	96	7	levels	level	NOUN
app-795	96	8	can	can	AUX
app-795	96	9	lead	lead	VERB
app-795	96	10	to	to	ADP
app-795	96	11	decreased	decrease	VERB
app-795	96	12	concentrations	concentration	NOUN
app-795	96	13	of	of	ADP
app-795	96	14	emotion	emotion	NOUN
app-795	96	15	-	-	PUNCT
app-795	96	16	regulating	regulate	VERB
app-795	96	17	neurotransmitters	neurotransmitter	NOUN
app-795	96	18	,	,	PUNCT
app-795	96	19	mainly	mainly	ADV
app-795	96	20	through	through	ADP
app-795	96	21	their	their	PRON
app-795	96	22	increased	increase	VERB
app-795	96	23	reuptake	reuptake	NOUN
app-795	96	24	by	by	ADP
app-795	96	25	presynaptic	presynaptic	ADJ
app-795	96	26	terminals	terminal	NOUN
app-795	96	27	[	[	X
app-795	96	28	8	8	NUM
app-795	96	29	,	,	PUNCT
app-795	96	30	9	9	NUM
app-795	96	31	]	]	PUNCT
app-795	96	32	.	.	PUNCT
app-795	97	1	inflammatory	inflammatory	ADJ
app-795	97	2	cytokines	cytokine	NOUN
app-795	97	3	stimulate	stimulate	VERB
app-795	97	4	a	a	DET
app-795	97	5	specific	specific	ADJ
app-795	97	6	enzyme	enzyme	NOUN
app-795	97	7	that	that	PRON
app-795	97	8	converts	convert	VERB
app-795	97	9	tryptophan	tryptophan	NOUN
app-795	97	10	into	into	ADP
app-795	97	11	kynurenine	kynurenine	NOUN
app-795	97	12	,	,	PUNCT
app-795	97	13	a	a	DET
app-795	97	14	neurotoxic	neurotoxic	ADJ
app-795	97	15	metabolite	metabolite	NOUN
app-795	97	16	.	.	PUNCT
app-795	98	1	this	this	DET
app-795	98	2	neurotoxin	neurotoxin	NOUN
app-795	98	3	activates	activate	VERB
app-795	98	4	glutamatergic	glutamatergic	ADJ
app-795	98	5	pathways	pathway	NOUN
app-795	98	6	,	,	PUNCT
app-795	98	7	promoting	promote	VERB
app-795	98	8	excitotoxic	excitotoxic	ADJ
app-795	98	9	damage	damage	NOUN
app-795	98	10	and	and	CCONJ
app-795	98	11	reducing	reduce	VERB
app-795	98	12	levels	level	NOUN
app-795	98	13	of	of	ADP
app-795	98	14	brain	brain	NOUN
app-795	98	15	-	-	PUNCT
app-795	98	16	derived	derive	VERB
app-795	98	17	neurotrophic	neurotrophic	ADJ
app-795	98	18	factor	factor	NOUN
app-795	98	19	(	(	PUNCT
app-795	98	20	bdnf	bdnf	PROPN
app-795	98	21	)	)	PUNCT
app-795	98	22	.	.	PUNCT
app-795	99	1	these	these	DET
app-795	99	2	neurobiological	neurobiological	ADJ
app-795	99	3	changes	change	NOUN
app-795	99	4	heighten	heighten	VERB
app-795	99	5	vulnerability	vulnerability	NOUN
app-795	99	6	to	to	ADP
app-795	99	7	anxiety	anxiety	NOUN
app-795	99	8	and	and	CCONJ
app-795	99	9	cognitive	cognitive	ADJ
app-795	99	10	deficits	deficit	NOUN
app-795	99	11	,	,	PUNCT
app-795	99	12	the	the	DET
app-795	99	13	clinical	clinical	ADJ
app-795	99	14	signs	sign	NOUN
app-795	99	15	commonly	commonly	ADV
app-795	99	16	observed	observe	VERB
app-795	99	17	in	in	ADP
app-795	99	18	anxiety	anxiety	NOUN
app-795	99	19	and	and	CCONJ
app-795	99	20	depressive	depressive	ADJ
app-795	99	21	disorders	disorder	NOUN
app-795	99	22	[	[	X
app-795	99	23	9	9	NUM
app-795	99	24	]	]	PUNCT
app-795	99	25	.	.	PUNCT
app-795	100	1	in	in	ADP
app-795	100	2	addition	addition	NOUN
app-795	100	3	,	,	PUNCT
app-795	100	4	individuals	individual	NOUN
app-795	100	5	suffering	suffer	VERB
app-795	100	6	from	from	ADP
app-795	100	7	anxiety	anxiety	NOUN
app-795	100	8	and	and	CCONJ
app-795	100	9	depression	depression	NOUN
app-795	100	10	may	may	AUX
app-795	100	11	also	also	ADV
app-795	100	12	experience	experience	VERB
app-795	100	13	adverse	adverse	ADJ
app-795	100	14	oral	oral	ADJ
app-795	100	15	health	health	NOUN
app-795	100	16	outcomes	outcome	NOUN
app-795	100	17	.	.	PUNCT
app-795	101	1	these	these	DET
app-795	101	2	individuals	individual	NOUN
app-795	101	3	experience	experience	VERB
app-795	101	4	persistent	persistent	ADJ
app-795	101	5	fatigue	fatigue	NOUN
app-795	101	6	,	,	PUNCT
app-795	101	7	decreased	decrease	VERB
app-795	101	8	motivation	motivation	NOUN
app-795	101	9	,	,	PUNCT
app-795	101	10	and	and	CCONJ
app-795	101	11	neglect	neglect	NOUN
app-795	101	12	of	of	ADP
app-795	101	13	self	self	NOUN
app-795	101	14	-	-	PUNCT
app-795	101	15	care	care	NOUN
app-795	101	16	routines	routine	NOUN
app-795	101	17	.	.	PUNCT
app-795	102	1	these	these	DET
app-795	102	2	symptoms	symptom	NOUN
app-795	102	3	may	may	AUX
app-795	102	4	result	result	VERB
app-795	102	5	in	in	ADP
app-795	102	6	less	less	ADV
app-795	102	7	frequent	frequent	ADJ
app-795	102	8	tooth	tooth	NOUN
app-795	102	9	brushing	brushing	NOUN
app-795	102	10	and	and	CCONJ
app-795	102	11	flossing	flossing	NOUN
app-795	102	12	,	,	PUNCT
app-795	102	13	missed	miss	VERB
app-795	102	14	dental	dental	ADJ
app-795	102	15	check	check	NOUN
app-795	102	16	-	-	PUNCT
app-795	102	17	ups	up	NOUN
app-795	102	18	,	,	PUNCT
app-795	102	19	or	or	CCONJ
app-795	102	20	the	the	DET
app-795	102	21	emergence	emergence	NOUN
app-795	102	22	of	of	ADP
app-795	102	23	harmful	harmful	ADJ
app-795	102	24	oral	oral	ADJ
app-795	102	25	habits	habit	NOUN
app-795	102	26	such	such	ADJ
app-795	102	27	as	as	ADP
app-795	102	28	teeth	tooth	NOUN
app-795	102	29	grinding	grinding	NOUN
app-795	102	30	,	,	PUNCT
app-795	102	31	tobacco	tobacco	NOUN
app-795	102	32	use	use	NOUN
app-795	102	33	,	,	PUNCT
app-795	102	34	or	or	CCONJ
app-795	102	35	increased	increase	VERB
app-795	102	36	consumption	consumption	NOUN
app-795	102	37	of	of	ADP
app-795	102	38	sugary	sugary	ADJ
app-795	102	39	foods	food	NOUN
app-795	102	40	.	.	PUNCT
app-795	103	1	these	these	DET
app-795	103	2	habits	habit	NOUN
app-795	103	3	encourage	encourage	VERB
app-795	103	4	the	the	DET
app-795	103	5	accumulation	accumulation	NOUN
app-795	103	6	of	of	ADP
app-795	103	7	dental	dental	ADJ
app-795	103	8	plaque	plaque	NOUN
app-795	103	9	,	,	PUNCT
app-795	103	10	leading	lead	VERB
app-795	103	11	to	to	ADP
app-795	103	12	gingival	gingival	NOUN
app-795	103	13	inflammation	inflammation	NOUN
app-795	103	14	,	,	PUNCT
app-795	103	15	which	which	PRON
app-795	103	16	progresses	progress	VERB
app-795	103	17	to	to	ADP
app-795	103	18	periodontitis	periodontitis	NOUN
app-795	103	19	[	[	X
app-795	103	20	10	10	NUM
app-795	103	21	]	]	PUNCT
app-795	103	22	.	.	PUNCT
app-795	104	1	dysregulation	dysregulation	NOUN
app-795	104	2	of	of	ADP
app-795	104	3	the	the	DET
app-795	104	4	immune	immune	ADJ
app-795	104	5	system	system	NOUN
app-795	104	6	forms	form	VERB
app-795	104	7	a	a	DET
app-795	104	8	causal	causal	ADJ
app-795	104	9	link	link	NOUN
app-795	104	10	between	between	ADP
app-795	104	11	psychiatric	psychiatric	ADJ
app-795	104	12	conditions	condition	NOUN
app-795	104	13	and	and	CCONJ
app-795	104	14	periodontal	periodontal	ADJ
app-795	104	15	pathology	pathology	NOUN
app-795	104	16	[	[	X
app-795	104	17	11	11	NUM
app-795	104	18	]	]	PUNCT
app-795	104	19	.	.	PUNCT
app-795	105	1	multiple	multiple	ADJ
app-795	105	2	investigations	investigation	NOUN
app-795	105	3	reveal	reveal	VERB
app-795	105	4	that	that	SCONJ
app-795	105	5	depressive	depressive	ADJ
app-795	105	6	states	state	NOUN
app-795	105	7	are	be	AUX
app-795	105	8	characterized	characterize	VERB
app-795	105	9	by	by	ADP
app-795	105	10	increased	increase	VERB
app-795	105	11	production	production	NOUN
app-795	105	12	of	of	ADP
app-795	105	13	pro	pro	ADJ
app-795	105	14	-	-	ADJ
app-795	105	15	inflammatory	inflammatory	ADJ
app-795	105	16	cytokines	cytokine	NOUN
app-795	105	17	by	by	ADP
app-795	105	18	the	the	DET
app-795	105	19	central	central	ADJ
app-795	105	20	microglia	microglia	NOUN
app-795	105	21	.	.	PUNCT
app-795	106	1	the	the	DET
app-795	106	2	chemokine	chemokine	ADJ
app-795	106	3	monocyte	monocyte	NOUN
app-795	106	4	chemoattractant	chemoattractant	PROPN
app-795	106	5	protein-1	protein-1	PROPN
app-795	106	6	(	(	PUNCT
app-795	106	7	mcp-1	mcp-1	NOUN
app-795	106	8	)	)	PUNCT
app-795	106	9	is	be	AUX
app-795	106	10	pivotal	pivotal	ADJ
app-795	106	11	in	in	ADP
app-795	106	12	directing	direct	VERB
app-795	106	13	monocyte	monocyte	NOUN
app-795	106	14	migration	migration	NOUN
app-795	106	15	to	to	ADP
app-795	106	16	emotional	emotional	ADJ
app-795	106	17	brain	brain	NOUN
app-795	106	18	regions	region	NOUN
app-795	106	19	.	.	PUNCT
app-795	107	1	these	these	PRON
app-795	107	2	include	include	VERB
app-795	107	3	the	the	DET
app-795	107	4	amygdala	amygdala	NOUN
app-795	107	5	and	and	CCONJ
app-795	107	6	hippocampus	hippocampus	PROPN
app-795	107	7	—	—	PUNCT
app-795	107	8	structures	structure	NOUN
app-795	107	9	that	that	PRON
app-795	107	10	are	be	AUX
app-795	107	11	fundamental	fundamental	ADJ
app-795	107	12	to	to	ADP
app-795	107	13	the	the	DET
app-795	107	14	processing	processing	NOUN
app-795	107	15	of	of	ADP
app-795	107	16	fear	fear	NOUN
app-795	107	17	and	and	CCONJ
app-795	107	18	the	the	DET
app-795	107	19	encoding	encoding	NOUN
app-795	107	20	of	of	ADP
app-795	107	21	emotional	emotional	ADJ
app-795	107	22	memories	memory	NOUN
app-795	107	23	[	[	X
app-795	107	24	12	12	NUM
app-795	107	25	]	]	PUNCT
app-795	107	26	.	.	PUNCT
app-795	108	1	periodontitis	periodontitis	NOUN
app-795	108	2	:	:	PUNCT
app-795	108	3	immune	immune	ADJ
app-795	108	4	imbalance	imbalance	NOUN
app-795	108	5	and	and	CCONJ
app-795	108	6	the	the	DET
app-795	108	7	impact	impact	NOUN
app-795	108	8	of	of	ADP
app-795	108	9	stress	stress	NOUN
app-795	108	10	periodontitis	periodontitis	NOUN
app-795	108	11	is	be	AUX
app-795	108	12	a	a	DET
app-795	108	13	chronic	chronic	ADJ
app-795	108	14	inflammatory	inflammatory	ADJ
app-795	108	15	ailment	ailment	NOUN
app-795	108	16	predominantly	predominantly	ADV
app-795	108	17	caused	cause	VERB
app-795	108	18	by	by	ADP
app-795	108	19	plaque	plaque	NOUN
app-795	108	20	accumulation	accumulation	NOUN
app-795	108	21	,	,	PUNCT
app-795	108	22	which	which	PRON
app-795	108	23	modifies	modify	VERB
app-795	108	24	the	the	DET
app-795	108	25	composition	composition	NOUN
app-795	108	26	of	of	ADP
app-795	108	27	the	the	DET
app-795	108	28	oral	oral	ADJ
app-795	108	29	microflora	microflora	NOUN
app-795	108	30	to	to	PART
app-795	108	31	incline	incline	VERB
app-795	108	32	towards	towards	ADP
app-795	108	33	a	a	DET
app-795	108	34	more	more	ADV
app-795	108	35	virulent	virulent	ADJ
app-795	108	36	gram	gram	NOUN
app-795	108	37	-	-	PUNCT
app-795	108	38	negative	negative	ADJ
app-795	108	39	species	specie	NOUN
app-795	108	40	.	.	PUNCT
app-795	109	1	this	this	PRON
app-795	109	2	provokes	provoke	VERB
app-795	109	3	the	the	DET
app-795	109	4	host	host	NOUN
app-795	109	5	’s	’s	PART
app-795	109	6	immune	immune	ADJ
app-795	109	7	response	response	NOUN
app-795	109	8	.	.	PUNCT
app-795	110	1	in	in	ADP
app-795	110	2	the	the	DET
app-795	110	3	initial	initial	ADJ
app-795	110	4	phase	phase	NOUN
app-795	110	5	,	,	PUNCT
app-795	110	6	the	the	DET
app-795	110	7	buildup	buildup	NOUN
app-795	110	8	of	of	ADP
app-795	110	9	plaque	plaque	NOUN
app-795	110	10	attracts	attract	VERB
app-795	110	11	neutrophils	neutrophil	NOUN
app-795	110	12	to	to	ADP
app-795	110	13	the	the	DET
app-795	110	14	affected	affect	VERB
app-795	110	15	site	site	NOUN
app-795	110	16	,	,	PUNCT
app-795	110	17	resulting	result	VERB
app-795	110	18	in	in	ADP
app-795	110	19	the	the	DET
app-795	110	20	formation	formation	NOUN
app-795	110	21	of	of	ADP
app-795	110	22	an	an	DET
app-795	110	23	early	early	ADJ
app-795	110	24	lesion	lesion	NOUN
app-795	110	25	.	.	PUNCT
app-795	111	1	if	if	SCONJ
app-795	111	2	inflammation	inflammation	NOUN
app-795	111	3	persists	persist	VERB
app-795	111	4	,	,	PUNCT
app-795	111	5	adaptive	adaptive	ADJ
app-795	111	6	t	t	NOUN
app-795	111	7	and	and	CCONJ
app-795	111	8	b	b	PROPN
app-795	111	9	lymphocytes	lymphocyte	NOUN
app-795	111	10	migrate	migrate	VERB
app-795	111	11	into	into	ADP
app-795	111	12	the	the	DET
app-795	111	13	periodontal	periodontal	ADJ
app-795	111	14	tissues	tissue	NOUN
app-795	111	15	.	.	PUNCT
app-795	112	1	these	these	DET
app-795	112	2	cells	cell	NOUN
app-795	112	3	release	release	VERB
app-795	112	4	cytokines	cytokine	NOUN
app-795	112	5	that	that	PRON
app-795	112	6	contribute	contribute	VERB
app-795	112	7	to	to	ADP
app-795	112	8	the	the	DET
app-795	112	9	connective	connective	ADJ
app-795	112	10	tissue	tissue	NOUN
app-795	112	11	breakdown	breakdown	NOUN
app-795	112	12	and	and	CCONJ
app-795	112	13	resorption	resorption	NOUN
app-795	112	14	of	of	ADP
app-795	112	15	alveolar	alveolar	ADJ
app-795	112	16	bone	bone	NOUN
app-795	112	17	[	[	X
app-795	112	18	13	13	NUM
app-795	112	19	]	]	PUNCT
app-795	112	20	.	.	PUNCT
app-795	113	1	a	a	DET
app-795	113	2	recent	recent	ADJ
app-795	113	3	study	study	NOUN
app-795	113	4	has	have	AUX
app-795	113	5	shown	show	VERB
app-795	113	6	that	that	SCONJ
app-795	113	7	psychological	psychological	ADJ
app-795	113	8	stress	stress	NOUN
app-795	113	9	plays	play	VERB
app-795	113	10	a	a	DET
app-795	113	11	significant	significant	ADJ
app-795	113	12	role	role	NOUN
app-795	113	13	in	in	ADP
app-795	113	14	the	the	DET
app-795	113	15	progression	progression	NOUN
app-795	113	16	of	of	ADP
app-795	113	17	periodontal	periodontal	ADJ
app-795	113	18	disease	disease	NOUN
app-795	113	19	[	[	X
app-795	113	20	14	14	NUM
app-795	113	21	]	]	PUNCT
app-795	113	22	.	.	PUNCT
app-795	114	1	elevated	elevated	ADJ
app-795	114	2	cortisol	cortisol	ADJ
app-795	114	3	levels	level	NOUN
app-795	114	4	associated	associate	VERB
app-795	114	5	with	with	ADP
app-795	114	6	stress	stress	NOUN
app-795	114	7	can	can	AUX
app-795	114	8	impair	impair	VERB
app-795	114	9	neutrophil	neutrophil	ADJ
app-795	114	10	chemotaxis	chemotaxis	ADJ
app-795	114	11	,	,	PUNCT
app-795	114	12	macrophage	macrophage	ADJ
app-795	114	13	activity	activity	NOUN
app-795	114	14	,	,	PUNCT
app-795	114	15	and	and	CCONJ
app-795	114	16	natural	natural	ADJ
app-795	114	17	killer	killer	NOUN
app-795	114	18	cell	cell	NOUN
app-795	114	19	responses	response	NOUN
app-795	114	20	.	.	PUNCT
app-795	115	1	these	these	DET
app-795	115	2	immune	immune	ADJ
app-795	115	3	alterations	alteration	NOUN
app-795	115	4	reduce	reduce	VERB
app-795	115	5	the	the	DET
app-795	115	6	body	body	NOUN
app-795	115	7	’s	’s	PART
app-795	115	8	ability	ability	NOUN
app-795	115	9	to	to	PART
app-795	115	10	defend	defend	VERB
app-795	115	11	against	against	ADP
app-795	115	12	pathogenic	pathogenic	ADJ
app-795	115	13	bacteria	bacteria	NOUN
app-795	115	14	,	,	PUNCT
app-795	115	15	enabling	enable	VERB
app-795	115	16	periodontal	periodontal	ADJ
app-795	115	17	microorganisms	microorganism	NOUN
app-795	115	18	like	like	ADP
app-795	115	19	porphyromonas	porphyromona	NOUN
app-795	115	20	gingivalis	gingivalis	VERB
app-795	115	21	to	to	PART
app-795	115	22	proliferate	proliferate	VERB
app-795	115	23	.	.	PUNCT
app-795	116	1	in	in	ADP
app-795	116	2	addition	addition	NOUN
app-795	116	3	,	,	PUNCT
app-795	116	4	chronic	chronic	ADJ
app-795	116	5	stress	stress	NOUN
app-795	116	6	increases	increase	VERB
app-795	116	7	the	the	DET
app-795	116	8	production	production	NOUN
app-795	116	9	of	of	ADP
app-795	116	10	pro	pro	ADJ
app-795	116	11	-	-	ADJ
app-795	116	12	inflammatory	inflammatory	ADJ
app-795	116	13	cytokines	cytokine	NOUN
app-795	116	14	,	,	PUNCT
app-795	116	15	including	include	VERB
app-795	116	16	interleukin-6	interleukin-6	NUM
app-795	116	17	(	(	PUNCT
app-795	116	18	il-6	il-6	NUM
app-795	116	19	)	)	PUNCT
app-795	116	20	and	and	CCONJ
app-795	116	21	tumor	tumor	NOUN
app-795	116	22	necrosis	necrosis	NOUN
app-795	116	23	factor	factor	NOUN
app-795	116	24	-	-	PUNCT
app-795	116	25	alpha	alpha	NOUN
app-795	116	26	(	(	PUNCT
app-795	116	27	tnf	tnf	PROPN
app-795	116	28	-	-	PUNCT
app-795	116	29	α	α	NOUN
app-795	116	30	)	)	PUNCT
app-795	116	31	.	.	PUNCT
app-795	117	1	these	these	DET
app-795	117	2	cytokines	cytokine	NOUN
app-795	117	3	are	be	AUX
app-795	117	4	involved	involve	VERB
app-795	117	5	in	in	ADP
app-795	117	6	the	the	DET
app-795	117	7	degradation	degradation	NOUN
app-795	117	8	of	of	ADP
app-795	117	9	periodontal	periodontal	ADJ
app-795	117	10	tissues	tissue	NOUN
app-795	118	1	[	[	X
app-795	118	2	3	3	NUM
app-795	118	3	]	]	PUNCT
app-795	118	4	.	.	PUNCT
app-795	119	1	activation	activation	NOUN
app-795	119	2	of	of	ADP
app-795	119	3	the	the	DET
app-795	119	4	sympathetic	sympathetic	ADJ
app-795	119	5	nervous	nervous	ADJ
app-795	119	6	system	system	NOUN
app-795	119	7	under	under	ADP
app-795	119	8	stressful	stressful	ADJ
app-795	119	9	conditions	condition	NOUN
app-795	119	10	has	have	VERB
app-795	119	11	significant	significant	ADJ
app-795	119	12	consequences	consequence	NOUN
app-795	119	13	on	on	ADP
app-795	119	14	periodontal	periodontal	ADJ
app-795	119	15	health	health	NOUN
app-795	120	1	[	[	X
app-795	120	2	15	15	NUM
app-795	120	3	,	,	PUNCT
app-795	120	4	16	16	NUM
app-795	120	5	]	]	PUNCT
app-795	120	6	.	.	PUNCT
app-795	121	1	increased	increase	VERB
app-795	121	2	autonomic	autonomic	ADJ
app-795	121	3	activity	activity	NOUN
app-795	121	4	is	be	AUX
app-795	121	5	indicated	indicate	VERB
app-795	121	6	by	by	ADP
app-795	121	7	higher	high	ADJ
app-795	121	8	concentrations	concentration	NOUN
app-795	121	9	of	of	ADP
app-795	121	10	salivary	salivary	ADJ
app-795	121	11	alpha	alpha	NOUN
app-795	121	12	-	-	PUNCT
app-795	121	13	amylase	amylase	NOUN
app-795	121	14	and	and	CCONJ
app-795	121	15	chromogranin	chromogranin	NOUN
app-795	121	16	-	-	PUNCT
app-795	121	17	a.	a.	NOUN
app-795	121	18	both	both	PRON
app-795	121	19	are	be	AUX
app-795	121	20	acknowledged	acknowledge	VERB
app-795	121	21	as	as	ADP
app-795	121	22	markers	marker	NOUN
app-795	121	23	of	of	ADP
app-795	121	24	sympathetic	sympathetic	ADJ
app-795	121	25	stimulation	stimulation	NOUN
app-795	121	26	.	.	PUNCT
app-795	122	1	these	these	DET
app-795	122	2	biomarkers	biomarker	NOUN
app-795	122	3	lead	lead	VERB
app-795	122	4	to	to	ADP
app-795	122	5	reduced	reduce	VERB
app-795	122	6	saliva	saliva	NOUN
app-795	122	7	and	and	CCONJ
app-795	122	8	alterations	alteration	NOUN
app-795	122	9	in	in	ADP
app-795	122	10	its	its	PRON
app-795	122	11	composition	composition	NOUN
app-795	122	12	,	,	PUNCT
app-795	122	13	creating	create	VERB
app-795	122	14	the	the	DET
app-795	122	15	conditions	condition	NOUN
app-795	122	16	that	that	PRON
app-795	122	17	encourage	encourage	VERB
app-795	122	18	the	the	DET
app-795	122	19	proliferation	proliferation	NOUN
app-795	122	20	of	of	ADP
app-795	122	21	pathogenic	pathogenic	ADJ
app-795	122	22	microorganisms	microorganism	NOUN
app-795	122	23	[	[	X
app-795	122	24	16	16	NUM
app-795	122	25	,	,	PUNCT
app-795	122	26	17	17	NUM
app-795	122	27	]	]	PUNCT
app-795	122	28	.	.	PUNCT
app-795	123	1	clinical	clinical	ADJ
app-795	123	2	observations	observation	NOUN
app-795	123	3	often	often	ADV
app-795	123	4	reveal	reveal	VERB
app-795	123	5	that	that	SCONJ
app-795	123	6	individuals	individual	NOUN
app-795	123	7	subjected	subject	VERB
app-795	123	8	to	to	ADP
app-795	123	9	prolonged	prolonged	ADJ
app-795	123	10	psychological	psychological	ADJ
app-795	123	11	stress	stress	NOUN
app-795	123	12	have	have	VERB
app-795	123	13	an	an	DET
app-795	123	14	increased	increase	VERB
app-795	123	15	risk	risk	NOUN
app-795	123	16	of	of	ADP
app-795	123	17	developing	develop	VERB
app-795	123	18	periodontitis	periodontitis	NOUN
app-795	123	19	.	.	PUNCT
app-795	124	1	these	these	DET
app-795	124	2	individuals	individual	NOUN
app-795	124	3	commonly	commonly	ADV
app-795	124	4	exhibit	exhibit	VERB
app-795	124	5	more	more	ADV
app-795	124	6	severe	severe	ADJ
app-795	124	7	clinical	clinical	ADJ
app-795	124	8	signs	sign	NOUN
app-795	124	9	of	of	ADP
app-795	124	10	periodontitis	periodontitis	NOUN
app-795	124	11	[	[	X
app-795	124	12	18	18	NUM
app-795	124	13	]	]	PUNCT
app-795	124	14	.	.	PUNCT
app-795	125	1	the	the	DET
app-795	125	2	interaction	interaction	NOUN
app-795	125	3	between	between	ADP
app-795	125	4	physiological	physiological	ADJ
app-795	125	5	mechanisms	mechanism	NOUN
app-795	125	6	and	and	CCONJ
app-795	125	7	behavioral	behavioral	ADJ
app-795	125	8	patterns	pattern	NOUN
app-795	125	9	connecting	connect	VERB
app-795	125	10	stress	stress	NOUN
app-795	125	11	with	with	ADP
app-795	125	12	periodontal	periodontal	ADJ
app-795	125	13	disease	disease	NOUN
app-795	125	14	emphasizes	emphasize	VERB
app-795	125	15	the	the	DET
app-795	125	16	importance	importance	NOUN
app-795	125	17	of	of	ADP
app-795	125	18	addressing	address	VERB
app-795	125	19	mental	mental	ADJ
app-795	125	20	health	health	NOUN
app-795	125	21	within	within	ADP
app-795	125	22	the	the	DET
app-795	125	23	framework	framework	NOUN
app-795	125	24	of	of	ADP
app-795	125	25	comprehensive	comprehensive	ADJ
app-795	125	26	periodontal	periodontal	ADJ
app-795	125	27	management	management	NOUN
app-795	125	28	.	.	PUNCT
app-795	126	1	vitamin	vitamin	NOUN
app-795	126	2	d	d	NOUN
app-795	126	3	as	as	ADP
app-795	126	4	a	a	DET
app-795	126	5	biological	biological	ADJ
app-795	126	6	connection	connection	NOUN
app-795	126	7	between	between	ADP
app-795	126	8	mental	mental	ADJ
app-795	126	9	well	well	ADV
app-795	126	10	-	-	PUNCT
app-795	126	11	being	being	NOUN
app-795	126	12	and	and	CCONJ
app-795	126	13	oral	oral	ADJ
app-795	126	14	health	health	NOUN
app-795	126	15	vitamin	vitamin	NOUN
app-795	126	16	d	d	PROPN
app-795	126	17	’s	’s	PART
app-795	126	18	role	role	NOUN
app-795	126	19	has	have	AUX
app-795	126	20	been	be	AUX
app-795	126	21	established	establish	VERB
app-795	126	22	as	as	ADP
app-795	126	23	an	an	DET
app-795	126	24	essential	essential	ADJ
app-795	126	25	hormone	hormone	NOUN
app-795	126	26	for	for	ADP
app-795	126	27	calcium	calcium	NOUN
app-795	126	28	regulation	regulation	NOUN
app-795	126	29	and	and	CCONJ
app-795	126	30	bone	bone	NOUN
app-795	126	31	health	health	NOUN
app-795	126	32	.	.	PUNCT
app-795	127	1	more	more	ADV
app-795	127	2	recently	recently	ADV
app-795	127	3	,	,	PUNCT
app-795	127	4	its	its	PRON
app-795	127	5	role	role	NOUN
app-795	127	6	in	in	ADP
app-795	127	7	modulating	modulate	VERB
app-795	127	8	immune	immune	ADJ
app-795	127	9	responses	response	NOUN
app-795	127	10	and	and	CCONJ
app-795	127	11	influencing	influence	VERB
app-795	127	12	neuroprotection	neuroprotection	NOUN
app-795	127	13	has	have	AUX
app-795	127	14	been	be	AUX
app-795	127	15	acknowledged	acknowledge	VERB
app-795	127	16	[	[	X
app-795	127	17	19	19	NUM
app-795	127	18	]	]	PUNCT
app-795	127	19	.	.	PUNCT
app-795	128	1	the	the	DET
app-795	128	2	active	active	ADJ
app-795	128	3	form	form	NOUN
app-795	128	4	,	,	PUNCT
app-795	128	5	1,25	1,25	NUM
app-795	128	6	-	-	PUNCT
app-795	128	7	dihydroxyvitamin	dihydroxyvitamin	ADJ
app-795	128	8	d₃	d₃	PROPN
app-795	128	9	,	,	PUNCT
app-795	128	10	exerts	exert	VERB
app-795	128	11	its	its	PRON
app-795	128	12	effects	effect	NOUN
app-795	128	13	by	by	ADP
app-795	128	14	binding	bind	VERB
app-795	128	15	to	to	ADP
app-795	128	16	vitamin	vitamin	NOUN
app-795	128	17	d	d	NOUN
app-795	128	18	receptors	receptor	NOUN
app-795	128	19	.	.	PUNCT
app-795	129	1	these	these	DET
app-795	129	2	receptors	receptor	NOUN
app-795	129	3	are	be	AUX
app-795	129	4	found	find	VERB
app-795	129	5	not	not	PART
app-795	129	6	only	only	ADV
app-795	129	7	in	in	ADP
app-795	129	8	conventional	conventional	ADJ
app-795	129	9	target	target	NOUN
app-795	129	10	tissues	tissue	NOUN
app-795	129	11	but	but	CCONJ
app-795	129	12	also	also	ADV
app-795	129	13	in	in	ADP
app-795	129	14	immune	immune	ADJ
app-795	129	15	cells	cell	NOUN
app-795	129	16	,	,	PUNCT
app-795	129	17	limbic	limbic	ADJ
app-795	129	18	areas	area	NOUN
app-795	129	19	of	of	ADP
app-795	129	20	the	the	DET
app-795	129	21	brain	brain	NOUN
app-795	129	22	,	,	PUNCT
app-795	129	23	and	and	CCONJ
app-795	129	24	periodontal	periodontal	ADJ
app-795	129	25	tissues	tissue	NOUN
app-795	129	26	[	[	X
app-795	129	27	20	20	NUM
app-795	129	28	,	,	PUNCT
app-795	129	29	21	21	NUM
app-795	129	30	]	]	PUNCT
app-795	129	31	.	.	PUNCT
app-795	130	1	vitamin	vitamin	NOUN
app-795	130	2	d	d	NOUN
app-795	130	3	is	be	AUX
app-795	130	4	vital	vital	ADJ
app-795	130	5	in	in	ADP
app-795	130	6	maintaining	maintain	VERB
app-795	130	7	periodontal	periodontal	ADJ
app-795	130	8	health	health	NOUN
app-795	130	9	by	by	ADP
app-795	130	10	regulating	regulate	VERB
app-795	130	11	inflammatory	inflammatory	ADJ
app-795	130	12	processes	process	NOUN
app-795	130	13	.	.	PUNCT
app-795	131	1	it	it	PRON
app-795	131	2	reduces	reduce	VERB
app-795	131	3	pro	pro	ADJ
app-795	131	4	-	-	ADJ
app-795	131	5	inflammatory	inflammatory	ADJ
app-795	131	6	cytokines	cytokine	NOUN
app-795	131	7	,	,	PUNCT
app-795	131	8	such	such	ADJ
app-795	131	9	as	as	ADP
app-795	131	10	interleukin-6	interleukin-6	NUM
app-795	131	11	and	and	CCONJ
app-795	131	12	tumor	tumor	NOUN
app-795	131	13	necrosis	necrosis	NOUN
app-795	131	14	factor	factor	NOUN
app-795	131	15	-	-	PUNCT
app-795	131	16	alpha	alpha	NOUN
app-795	131	17	.	.	PUNCT
app-795	132	1	this	this	DET
app-795	132	2	essential	essential	ADJ
app-795	132	3	vitamin	vitamin	NOUN
app-795	132	4	supports	support	VERB
app-795	132	5	the	the	DET
app-795	132	6	synthesis	synthesis	NOUN
app-795	132	7	of	of	ADP
app-795	132	8	anti	anti	ADJ
app-795	132	9	-	-	ADJ
app-795	132	10	inflammatory	inflammatory	ADJ
app-795	132	11	mediators	mediator	NOUN
app-795	132	12	.	.	PUNCT
app-795	133	1	in	in	ADP
app-795	133	2	addition	addition	NOUN
app-795	133	3	,	,	PUNCT
app-795	133	4	the	the	DET
app-795	133	5	active	active	ADJ
app-795	133	6	vitamin	vitamin	NOUN
app-795	133	7	d	d	NOUN
app-795	133	8	increases	increase	VERB
app-795	133	9	the	the	DET
app-795	133	10	production	production	NOUN
app-795	133	11	of	of	ADP
app-795	133	12	cathelicidin	cathelicidin	NOUN
app-795	133	13	,	,	PUNCT
app-795	133	14	an	an	DET
app-795	133	15	antimicrobial	antimicrobial	ADJ
app-795	133	16	peptide	peptide	NOUN
app-795	133	17	that	that	PRON
app-795	133	18	protects	protect	VERB
app-795	133	19	against	against	ADP
app-795	133	20	periodontal	periodontal	ADJ
app-795	133	21	pathogens	pathogen	NOUN
app-795	133	22	.	.	PUNCT
app-795	134	1	by	by	ADP
app-795	134	2	regulating	regulate	VERB
app-795	134	3	bone	bone	NOUN
app-795	134	4	remodeling	remodeling	NOUN
app-795	134	5	,	,	PUNCT
app-795	134	6	vitamin	vitamin	NOUN
app-795	134	7	d	d	NOUN
app-795	134	8	contributes	contribute	VERB
app-795	134	9	to	to	ADP
app-795	134	10	bone	bone	NOUN
app-795	134	11	formation	formation	NOUN
app-795	134	12	and	and	CCONJ
app-795	134	13	limits	limit	VERB
app-795	134	14	bone	bone	NOUN
app-795	134	15	loss	loss	NOUN
app-795	134	16	.	.	PUNCT
app-795	135	1	these	these	DET
app-795	135	2	processes	process	VERB
app-795	135	3	help	help	VERB
app-795	135	4	to	to	PART
app-795	135	5	maintain	maintain	VERB
app-795	135	6	alveolar	alveolar	ADJ
app-795	135	7	bone	bone	NOUN
app-795	135	8	integrity	integrity	NOUN
app-795	135	9	and	and	CCONJ
app-795	135	10	slow	slow	VERB
app-795	135	11	the	the	DET
app-795	135	12	progression	progression	NOUN
app-795	135	13	of	of	ADP
app-795	135	14	periodontal	periodontal	ADJ
app-795	135	15	disease	disease	NOUN
app-795	135	16	[	[	X
app-795	135	17	21	21	NUM
app-795	135	18	]	]	PUNCT
app-795	135	19	.	.	PUNCT
app-795	136	1	studies	study	NOUN
app-795	136	2	have	have	AUX
app-795	136	3	reported	report	VERB
app-795	136	4	a	a	DET
app-795	136	5	negative	negative	ADJ
app-795	136	6	correlation	correlation	NOUN
app-795	136	7	between	between	ADP
app-795	136	8	vitamin	vitamin	NOUN
app-795	136	9	d	d	NOUN
app-795	136	10	levels	level	NOUN
app-795	136	11	and	and	CCONJ
app-795	136	12	the	the	DET
app-795	136	13	severity	severity	NOUN
app-795	136	14	of	of	ADP
app-795	136	15	periodontal	periodontal	ADJ
app-795	136	16	disease	disease	NOUN
app-795	136	17	.	.	PUNCT
app-795	137	1	this	this	PRON
app-795	137	2	suggests	suggest	VERB
app-795	137	3	that	that	SCONJ
app-795	137	4	insufficient	insufficient	ADJ
app-795	137	5	vitamin	vitamin	NOUN
app-795	137	6	d	d	NOUN
app-795	137	7	may	may	AUX
app-795	137	8	be	be	AUX
app-795	137	9	associated	associate	VERB
app-795	137	10	with	with	ADP
app-795	137	11	severe	severe	ADJ
app-795	137	12	periodontal	periodontal	ADJ
app-795	137	13	tissue	tissue	NOUN
app-795	137	14	breakdown	breakdown	NOUN
app-795	137	15	[	[	X
app-795	137	16	22	22	NUM
app-795	137	17	,	,	PUNCT
app-795	137	18	23	23	NUM
app-795	137	19	]	]	PUNCT
app-795	137	20	.	.	PUNCT
app-795	138	1	there	there	PRON
app-795	138	2	is	be	VERB
app-795	138	3	strong	strong	ADJ
app-795	138	4	evidence	evidence	NOUN
app-795	138	5	linking	link	VERB
app-795	138	6	vitamin	vitamin	NOUN
app-795	138	7	d	d	NOUN
app-795	138	8	status	status	NOUN
app-795	138	9	to	to	ADP
app-795	138	10	mental	mental	ADJ
app-795	138	11	health	health	NOUN
app-795	138	12	.	.	PUNCT
app-795	139	1	key	key	ADJ
app-795	139	2	brain	brain	NOUN
app-795	139	3	regions	region	NOUN
app-795	139	4	involved	involve	VERB
app-795	139	5	in	in	ADP
app-795	139	6	emotional	emotional	ADJ
app-795	139	7	regulation	regulation	NOUN
app-795	139	8	,	,	PUNCT
app-795	139	9	such	such	ADJ
app-795	139	10	as	as	ADP
app-795	139	11	the	the	DET
app-795	139	12	hippocampus	hippocampus	NOUN
app-795	139	13	,	,	PUNCT
app-795	139	14	amygdala	amygdala	NOUN
app-795	139	15	,	,	PUNCT
app-795	139	16	and	and	CCONJ
app-795	139	17	prefrontal	prefrontal	ADJ
app-795	139	18	cortex	cortex	NOUN
app-795	139	19	,	,	PUNCT
app-795	139	20	have	have	VERB
app-795	139	21	receptors	receptor	NOUN
app-795	139	22	for	for	ADP
app-795	139	23	vitamin	vitamin	NOUN
app-795	139	24	d	d	NOUN
app-795	139	25	and	and	CCONJ
app-795	139	26	the	the	DET
app-795	139	27	enzyme	enzyme	NOUN
app-795	139	28	responsible	responsible	ADJ
app-795	139	29	for	for	ADP
app-795	139	30	converting	convert	VERB
app-795	139	31	vitamin	vitamin	NOUN
app-795	139	32	d	d	NOUN
app-795	139	33	to	to	ADP
app-795	139	34	its	its	PRON
app-795	139	35	active	active	ADJ
app-795	139	36	form	form	NOUN
app-795	139	37	.	.	PUNCT
app-795	140	1	vitamin	vitamin	NOUN
app-795	140	2	d	d	NOUN
app-795	140	3	increases	increase	VERB
app-795	140	4	the	the	DET
app-795	140	5	expression	expression	NOUN
app-795	140	6	of	of	ADP
app-795	140	7	tryptophan	tryptophan	NOUN
app-795	140	8	hydroxylase-2	hydroxylase-2	PROPN
app-795	140	9	,	,	PUNCT
app-795	140	10	the	the	DET
app-795	140	11	enzyme	enzyme	NOUN
app-795	140	12	necessary	necessary	ADJ
app-795	140	13	for	for	ADP
app-795	140	14	serotonin	serotonin	ADJ
app-795	140	15	synthesis	synthesis	NOUN
app-795	140	16	,	,	PUNCT
app-795	140	17	a	a	DET
app-795	140	18	neurotransmitter	neurotransmitter	NOUN
app-795	140	19	that	that	PRON
app-795	140	20	plays	play	VERB
app-795	140	21	a	a	DET
app-795	140	22	central	central	ADJ
app-795	140	23	role	role	NOUN
app-795	140	24	in	in	ADP
app-795	140	25	mood	mood	NOUN
app-795	140	26	regulation	regulation	NOUN
app-795	140	27	.	.	PUNCT
app-795	141	1	as	as	SCONJ
app-795	141	2	serotonin	serotonin	NOUN
app-795	141	3	is	be	AUX
app-795	141	4	important	important	ADJ
app-795	141	5	for	for	ADP
app-795	141	6	emotional	emotional	ADJ
app-795	141	7	regulation	regulation	NOUN
app-795	141	8	,	,	PUNCT
app-795	141	9	cognitive	cognitive	ADJ
app-795	141	10	function	function	NOUN
app-795	141	11	,	,	PUNCT
app-795	141	12	and	and	CCONJ
app-795	141	13	mood	mood	NOUN
app-795	141	14	stability	stability	NOUN
app-795	141	15	,	,	PUNCT
app-795	141	16	inadequate	inadequate	ADJ
app-795	141	17	levels	level	NOUN
app-795	141	18	of	of	ADP
app-795	141	19	vitamin	vitamin	NOUN
app-795	141	20	d	d	NOUN
app-795	141	21	can	can	AUX
app-795	141	22	reduce	reduce	VERB
app-795	141	23	serotonin	serotonin	NOUN
app-795	141	24	production	production	NOUN
app-795	141	25	and	and	CCONJ
app-795	141	26	increase	increase	VERB
app-795	141	27	the	the	DET
app-795	141	28	risk	risk	NOUN
app-795	141	29	of	of	ADP
app-795	141	30	developing	develop	VERB
app-795	141	31	anxiety	anxiety	NOUN
app-795	141	32	and	and	CCONJ
app-795	141	33	depressive	depressive	ADJ
app-795	141	34	symptoms	symptom	NOUN
app-795	141	35	[	[	X
app-795	141	36	24	24	NUM
app-795	141	37	]	]	PUNCT
app-795	141	38	.	.	PUNCT
app-795	142	1	vitamin	vitamin	NOUN
app-795	142	2	d	d	NOUN
app-795	142	3	plays	play	VERB
app-795	142	4	an	an	DET
app-795	142	5	important	important	ADJ
app-795	142	6	role	role	NOUN
app-795	142	7	in	in	ADP
app-795	142	8	safeguarding	safeguard	VERB
app-795	142	9	neural	neural	ADJ
app-795	142	10	tissue	tissue	NOUN
app-795	142	11	by	by	ADP
app-795	142	12	improving	improve	VERB
app-795	142	13	mitochondrial	mitochondrial	ADJ
app-795	142	14	integrity	integrity	NOUN
app-795	142	15	and	and	CCONJ
app-795	142	16	reducing	reduce	VERB
app-795	142	17	oxidative	oxidative	ADJ
app-795	142	18	stress	stress	NOUN
app-795	142	19	.	.	PUNCT
app-795	143	1	it	it	PRON
app-795	143	2	stimulates	stimulate	VERB
app-795	143	3	antioxidants	antioxidant	NOUN
app-795	143	4	,	,	PUNCT
app-795	143	5	such	such	ADJ
app-795	143	6	as	as	ADP
app-795	143	7	glutathione	glutathione	NOUN
app-795	143	8	,	,	PUNCT
app-795	143	9	which	which	PRON
app-795	143	10	serve	serve	VERB
app-795	143	11	to	to	PART
app-795	143	12	reduce	reduce	VERB
app-795	143	13	the	the	DET
app-795	143	14	buildup	buildup	NOUN
app-795	143	15	of	of	ADP
app-795	143	16	reactive	reactive	ADJ
app-795	143	17	oxygen	oxygen	NOUN
app-795	143	18	species	specie	NOUN
app-795	143	19	in	in	ADP
app-795	143	20	brain	brain	NOUN
app-795	143	21	tissue	tissue	NOUN
app-795	143	22	.	.	PUNCT
app-795	144	1	deficiency	deficiency	NOUN
app-795	144	2	in	in	ADP
app-795	144	3	vitamin	vitamin	NOUN
app-795	144	4	d	d	NOUN
app-795	144	5	can	can	AUX
app-795	144	6	result	result	VERB
app-795	144	7	in	in	ADP
app-795	144	8	degeneration	degeneration	NOUN
app-795	144	9	of	of	ADP
app-795	144	10	gabaergic	gabaergic	ADJ
app-795	144	11	neurons	neuron	NOUN
app-795	144	12	.	.	PUNCT
app-795	145	1	this	this	DET
app-795	145	2	disruption	disruption	NOUN
app-795	145	3	disturbs	disturb	VERB
app-795	145	4	the	the	DET
app-795	145	5	equilibrium	equilibrium	NOUN
app-795	145	6	between	between	ADP
app-795	145	7	excitatory	excitatory	NOUN
app-795	145	8	and	and	CCONJ
app-795	145	9	inhibitory	inhibitory	ADJ
app-795	145	10	neurotransmitters	neurotransmitter	NOUN
app-795	145	11	,	,	PUNCT
app-795	145	12	leading	lead	VERB
app-795	145	13	to	to	ADP
app-795	145	14	a	a	DET
app-795	145	15	hyperactive	hyperactive	ADJ
app-795	145	16	amygdala	amygdala	NOUN
app-795	145	17	.	.	PUNCT
app-795	146	1	therefore	therefore	ADV
app-795	146	2	,	,	PUNCT
app-795	146	3	low	low	ADJ
app-795	146	4	vitamin	vitamin	NOUN
app-795	146	5	d	d	NOUN
app-795	146	6	status	status	NOUN
app-795	146	7	may	may	AUX
app-795	146	8	contribute	contribute	VERB
app-795	146	9	to	to	ADP
app-795	146	10	psychological	psychological	ADJ
app-795	146	11	health	health	NOUN
app-795	146	12	issues	issue	NOUN
app-795	146	13	and	and	CCONJ
app-795	146	14	periodontal	periodontal	ADJ
app-795	146	15	integrity	integrity	NOUN
app-795	146	16	issues	issue	NOUN
app-795	146	17	[	[	X
app-795	146	18	24	24	NUM
app-795	146	19	]	]	PUNCT
app-795	146	20	.	.	PUNCT
app-795	147	1	addressing	address	VERB
app-795	147	2	vitamin	vitamin	NOUN
app-795	147	3	d	d	NOUN
app-795	147	4	deficiency	deficiency	NOUN
app-795	147	5	may	may	AUX
app-795	147	6	offer	offer	VERB
app-795	147	7	therapeutic	therapeutic	ADJ
app-795	147	8	advantages	advantage	NOUN
app-795	147	9	in	in	ADP
app-795	147	10	both	both	CCONJ
app-795	147	11	mental	mental	ADJ
app-795	147	12	health	health	NOUN
app-795	147	13	and	and	CCONJ
app-795	147	14	oral	oral	ADJ
app-795	147	15	health	health	NOUN
app-795	147	16	areas	area	NOUN
app-795	147	17	.	.	PUNCT
app-795	148	1	stress	stress	NOUN
app-795	148	2	-	-	PUNCT
app-795	148	3	sensitive	sensitive	ADJ
app-795	148	4	salivary	salivary	ADJ
app-795	148	5	biomarkers	biomarker	NOUN
app-795	148	6	connecting	connect	VERB
app-795	148	7	oral	oral	ADJ
app-795	148	8	and	and	CCONJ
app-795	148	9	mental	mental	ADJ
app-795	148	10	health	health	NOUN
app-795	148	11	saliva	saliva	NOUN
app-795	148	12	is	be	AUX
app-795	148	13	a	a	DET
app-795	148	14	biological	biological	ADJ
app-795	148	15	fluid	fluid	NOUN
app-795	148	16	composed	compose	VERB
app-795	148	17	of	of	ADP
app-795	148	18	hormones	hormone	NOUN
app-795	148	19	,	,	PUNCT
app-795	148	20	cytokines	cytokine	NOUN
app-795	148	21	,	,	PUNCT
app-795	148	22	enzymes	enzyme	NOUN
app-795	148	23	,	,	PUNCT
app-795	148	24	and	and	CCONJ
app-795	148	25	peptides	peptide	NOUN
app-795	148	26	.	.	PUNCT
app-795	149	1	these	these	DET
app-795	149	2	molecules	molecule	NOUN
app-795	149	3	enter	enter	VERB
app-795	149	4	saliva	saliva	NOUN
app-795	149	5	through	through	ADP
app-795	149	6	both	both	CCONJ
app-795	149	7	transcellular	transcellular	ADJ
app-795	149	8	and	and	CCONJ
app-795	149	9	paracellular	paracellular	ADJ
app-795	149	10	transport	transport	NOUN
app-795	149	11	processes	process	NOUN
app-795	149	12	.	.	PUNCT
app-795	150	1	this	this	DET
app-795	150	2	results	result	VERB
app-795	150	3	in	in	ADP
app-795	150	4	a	a	DET
app-795	150	5	molecular	molecular	ADJ
app-795	150	6	composition	composition	NOUN
app-795	150	7	that	that	PRON
app-795	150	8	reflects	reflect	VERB
app-795	150	9	the	the	DET
app-795	150	10	state	state	NOUN
app-795	150	11	of	of	ADP
app-795	150	12	both	both	CCONJ
app-795	150	13	oral	oral	ADJ
app-795	150	14	and	and	CCONJ
app-795	150	15	systemic	systemic	ADJ
app-795	150	16	health	health	NOUN
app-795	150	17	.	.	PUNCT
app-795	151	1	saliva	saliva	NOUN
app-795	151	2	provides	provide	VERB
app-795	151	3	a	a	DET
app-795	151	4	non	non	ADJ
app-795	151	5	-	-	ADJ
app-795	151	6	invasive	invasive	ADJ
app-795	151	7	medium	medium	NOUN
app-795	151	8	for	for	ADP
app-795	151	9	studying	study	VERB
app-795	151	10	the	the	DET
app-795	151	11	interplay	interplay	NOUN
app-795	151	12	between	between	ADP
app-795	151	13	stress	stress	NOUN
app-795	151	14	-	-	PUNCT
app-795	151	15	related	relate	VERB
app-795	151	16	physiological	physiological	ADJ
app-795	151	17	changes	change	NOUN
app-795	151	18	and	and	CCONJ
app-795	151	19	oral	oral	ADJ
app-795	151	20	health	health	NOUN
app-795	151	21	conditions	condition	NOUN
app-795	151	22	.	.	PUNCT
app-795	152	1	its	its	PRON
app-795	152	2	correlation	correlation	NOUN
app-795	152	3	with	with	ADP
app-795	152	4	serum	serum	NOUN
app-795	152	5	biomarkers	biomarker	NOUN
app-795	152	6	strengthens	strengthen	VERB
app-795	152	7	its	its	PRON
app-795	152	8	utility	utility	NOUN
app-795	152	9	in	in	ADP
app-795	152	10	evaluating	evaluate	VERB
app-795	152	11	psychological	psychological	ADJ
app-795	152	12	and	and	CCONJ
app-795	152	13	dental	dental	ADJ
app-795	152	14	health	health	NOUN
app-795	152	15	[	[	X
app-795	152	16	25	25	NUM
app-795	152	17	,	,	PUNCT
app-795	152	18	26	26	NUM
app-795	152	19	]	]	PUNCT
app-795	152	20	.	.	PUNCT
app-795	153	1	this	this	PRON
app-795	153	2	underscores	underscore	VERB
app-795	153	3	the	the	DET
app-795	153	4	growing	grow	VERB
app-795	153	5	recognition	recognition	NOUN
app-795	153	6	of	of	ADP
app-795	153	7	saliva	saliva	NOUN
app-795	153	8	as	as	ADP
app-795	153	9	a	a	DET
app-795	153	10	valuable	valuable	ADJ
app-795	153	11	diagnostic	diagnostic	ADJ
app-795	153	12	tool	tool	NOUN
app-795	153	13	for	for	ADP
app-795	153	14	investigating	investigate	VERB
app-795	153	15	the	the	DET
app-795	153	16	relationship	relationship	NOUN
app-795	153	17	between	between	ADP
app-795	153	18	psychological	psychological	ADJ
app-795	153	19	factors	factor	NOUN
app-795	153	20	and	and	CCONJ
app-795	153	21	oral	oral	ADJ
app-795	153	22	health	health	NOUN
app-795	153	23	.	.	PUNCT
app-795	154	1	cortisol	cortisol	PROPN
app-795	154	2	remains	remain	VERB
app-795	154	3	one	one	NUM
app-795	154	4	of	of	ADP
app-795	154	5	the	the	DET
app-795	154	6	most	most	ADV
app-795	154	7	extensively	extensively	ADV
app-795	154	8	studied	study	VERB
app-795	154	9	salivary	salivary	ADJ
app-795	154	10	biomarkers	biomarker	NOUN
app-795	154	11	.	.	PUNCT
app-795	155	1	this	this	DET
app-795	155	2	steroid	steroid	NOUN
app-795	155	3	hormone	hormone	NOUN
app-795	155	4	is	be	AUX
app-795	155	5	recognized	recognize	VERB
app-795	155	6	as	as	ADP
app-795	155	7	a	a	DET
app-795	155	8	reliable	reliable	ADJ
app-795	155	9	indicator	indicator	NOUN
app-795	155	10	of	of	ADP
app-795	155	11	hypothalamic	hypothalamic	ADJ
app-795	155	12	-	-	PUNCT
app-795	155	13	pituitary	pituitary	ADJ
app-795	155	14	-	-	PUNCT
app-795	155	15	adrenal	adrenal	ADJ
app-795	155	16	(	(	PUNCT
app-795	155	17	hpa	hpa	NOUN
app-795	155	18	)	)	PUNCT
app-795	155	19	axis	axis	NOUN
app-795	155	20	activity	activity	NOUN
app-795	155	21	.	.	PUNCT
app-795	156	1	individuals	individual	NOUN
app-795	156	2	experiencing	experience	VERB
app-795	156	3	stress	stress	NOUN
app-795	156	4	frequently	frequently	ADV
app-795	156	5	exhibit	exhibit	VERB
app-795	156	6	increased	increase	VERB
app-795	156	7	concentrations	concentration	NOUN
app-795	156	8	of	of	ADP
app-795	156	9	salivary	salivary	ADJ
app-795	156	10	cortisol	cortisol	NOUN
app-795	157	1	[	[	X
app-795	157	2	14	14	NUM
app-795	157	3	]	]	PUNCT
app-795	157	4	.	.	PUNCT
app-795	158	1	although	although	SCONJ
app-795	158	2	cortisol	cortisol	NOUN
app-795	158	3	plays	play	VERB
app-795	158	4	a	a	DET
app-795	158	5	protective	protective	ADJ
app-795	158	6	role	role	NOUN
app-795	158	7	during	during	ADP
app-795	158	8	episodes	episode	NOUN
app-795	158	9	of	of	ADP
app-795	158	10	acute	acute	ADJ
app-795	158	11	stress	stress	NOUN
app-795	158	12	,	,	PUNCT
app-795	158	13	its	its	PRON
app-795	158	14	persistently	persistently	ADV
app-795	158	15	elevated	elevate	VERB
app-795	158	16	levels	level	NOUN
app-795	158	17	contribute	contribute	VERB
app-795	158	18	to	to	ADP
app-795	158	19	systemic	systemic	ADJ
app-795	158	20	inflammation	inflammation	NOUN
app-795	158	21	and	and	CCONJ
app-795	158	22	a	a	DET
app-795	158	23	compromised	compromise	VERB
app-795	158	24	local	local	ADJ
app-795	158	25	immune	immune	ADJ
app-795	158	26	response	response	NOUN
app-795	158	27	.	.	PUNCT
app-795	159	1	elevated	elevated	ADJ
app-795	159	2	salivary	salivary	ADJ
app-795	159	3	cortisol	cortisol	NOUN
app-795	159	4	is	be	AUX
app-795	159	5	associated	associate	VERB
app-795	159	6	with	with	ADP
app-795	159	7	increased	increase	VERB
app-795	159	8	periodontal	periodontal	ADJ
app-795	159	9	pocket	pocket	NOUN
app-795	159	10	depth	depth	NOUN
app-795	159	11	,	,	PUNCT
app-795	159	12	worsened	worsen	VERB
app-795	159	13	gingival	gingival	ADJ
app-795	159	14	inflammation	inflammation	NOUN
app-795	159	15	,	,	PUNCT
app-795	159	16	and	and	CCONJ
app-795	159	17	reduced	reduce	VERB
app-795	159	18	resistance	resistance	NOUN
app-795	159	19	to	to	ADP
app-795	159	20	oral	oral	ADJ
app-795	159	21	infections	infection	NOUN
app-795	159	22	[	[	X
app-795	159	23	14	14	NUM
app-795	159	24	,	,	PUNCT
app-795	159	25	27	27	NUM
app-795	159	26	]	]	PUNCT
app-795	159	27	.	.	PUNCT
app-795	160	1	interleukin-6	interleukin-6	NUM
app-795	160	2	(	(	PUNCT
app-795	160	3	il-6	il-6	NOUN
app-795	160	4	)	)	PUNCT
app-795	160	5	is	be	AUX
app-795	160	6	an	an	DET
app-795	160	7	important	important	ADJ
app-795	160	8	inflammatory	inflammatory	ADJ
app-795	160	9	marker	marker	NOUN
app-795	160	10	that	that	PRON
app-795	160	11	links	link	VERB
app-795	160	12	behavioral	behavioral	ADJ
app-795	160	13	conditions	condition	NOUN
app-795	160	14	with	with	ADP
app-795	160	15	oral	oral	ADJ
app-795	160	16	disorders	disorder	NOUN
app-795	160	17	.	.	PUNCT
app-795	161	1	this	this	DET
app-795	161	2	cytokine	cytokine	NOUN
app-795	161	3	plays	play	VERB
app-795	161	4	a	a	DET
app-795	161	5	central	central	ADJ
app-795	161	6	role	role	NOUN
app-795	161	7	in	in	ADP
app-795	161	8	immune	immune	ADJ
app-795	161	9	system	system	NOUN
app-795	161	10	regulation	regulation	NOUN
app-795	161	11	,	,	PUNCT
app-795	161	12	and	and	CCONJ
app-795	161	13	its	its	PRON
app-795	161	14	levels	level	NOUN
app-795	161	15	increase	increase	VERB
app-795	161	16	in	in	ADP
app-795	161	17	response	response	NOUN
app-795	161	18	to	to	ADP
app-795	161	19	both	both	PRON
app-795	161	20	emotional	emotional	ADJ
app-795	161	21	stress	stress	NOUN
app-795	161	22	and	and	CCONJ
app-795	161	23	periodontal	periodontal	ADJ
app-795	161	24	inflammation	inflammation	NOUN
app-795	161	25	.	.	PUNCT
app-795	162	1	elevated	elevated	ADJ
app-795	162	2	salivary	salivary	NOUN
app-795	162	3	il-6	il-6	NUM
app-795	162	4	is	be	AUX
app-795	162	5	associated	associate	VERB
app-795	162	6	with	with	ADP
app-795	162	7	greater	great	ADJ
app-795	162	8	osteoclastic	osteoclastic	NOUN
app-795	162	9	activity	activity	NOUN
app-795	162	10	,	,	PUNCT
app-795	162	11	connective	connective	ADJ
app-795	162	12	tissue	tissue	NOUN
app-795	162	13	breakdown	breakdown	NOUN
app-795	162	14	,	,	PUNCT
app-795	162	15	and	and	CCONJ
app-795	162	16	increased	increase	VERB
app-795	162	17	inflammatory	inflammatory	ADJ
app-795	162	18	cell	cell	NOUN
app-795	162	19	infiltration	infiltration	NOUN
app-795	162	20	in	in	ADP
app-795	162	21	periodontal	periodontal	ADJ
app-795	162	22	tissues	tissue	NOUN
app-795	162	23	[	[	X
app-795	162	24	28	28	NUM
app-795	162	25	]	]	PUNCT
app-795	162	26	.	.	PUNCT
app-795	163	1	it	it	PRON
app-795	163	2	influences	influence	VERB
app-795	163	3	behavior	behavior	NOUN
app-795	163	4	by	by	ADP
app-795	163	5	promoting	promote	VERB
app-795	163	6	neuroinflammation	neuroinflammation	NOUN
app-795	163	7	,	,	PUNCT
app-795	163	8	thereby	thereby	ADV
app-795	163	9	increasing	increase	VERB
app-795	163	10	an	an	DET
app-795	163	11	individual	individual	NOUN
app-795	163	12	’s	’s	PART
app-795	163	13	susceptibility	susceptibility	NOUN
app-795	163	14	to	to	ADP
app-795	163	15	anxiety	anxiety	NOUN
app-795	163	16	and	and	CCONJ
app-795	163	17	depression	depression	NOUN
app-795	163	18	[	[	X
app-795	163	19	29	29	NUM
app-795	163	20	]	]	PUNCT
app-795	163	21	.	.	PUNCT
app-795	164	1	the	the	DET
app-795	164	2	sympathetic	sympathetic	ADJ
app-795	164	3	nervous	nervous	ADJ
app-795	164	4	system	system	NOUN
app-795	164	5	's	's	PART
app-795	164	6	activity	activity	NOUN
app-795	164	7	can	can	AUX
app-795	164	8	be	be	AUX
app-795	164	9	assessed	assess	VERB
app-795	164	10	non	non	ADJ
app-795	164	11	-	-	ADJ
app-795	164	12	invasively	invasively	ADV
app-795	164	13	through	through	ADP
app-795	164	14	salivary	salivary	ADJ
app-795	164	15	alpha	alpha	NOUN
app-795	164	16	-	-	PUNCT
app-795	164	17	amylase	amylase	NOUN
app-795	164	18	[	[	X
app-795	164	19	30	30	NUM
app-795	164	20	]	]	PUNCT
app-795	164	21	.	.	PUNCT
app-795	165	1	this	this	DET
app-795	165	2	protein	protein	NOUN
app-795	165	3	alters	alter	VERB
app-795	165	4	saliva	saliva	NOUN
app-795	165	5	composition	composition	NOUN
app-795	165	6	and	and	CCONJ
app-795	165	7	oral	oral	ADJ
app-795	165	8	immunity	immunity	NOUN
app-795	165	9	,	,	PUNCT
app-795	165	10	impairs	impair	VERB
app-795	165	11	antibacterial	antibacterial	ADJ
app-795	165	12	defenses	defense	NOUN
app-795	165	13	,	,	PUNCT
app-795	165	14	and	and	CCONJ
app-795	165	15	heightens	heighten	VERB
app-795	165	16	the	the	DET
app-795	165	17	likelihood	likelihood	NOUN
app-795	165	18	of	of	ADP
app-795	165	19	periodontal	periodontal	ADJ
app-795	165	20	infections	infection	NOUN
app-795	165	21	[	[	X
app-795	165	22	17	17	NUM
app-795	165	23	]	]	PUNCT
app-795	165	24	.	.	PUNCT
app-795	166	1	chromogranin	chromogranin	PROPN
app-795	166	2	-	-	PUNCT
app-795	166	3	a	a	DET
app-795	166	4	(	(	PUNCT
app-795	166	5	cg	cg	NOUN
app-795	166	6	-	-	PUNCT
app-795	166	7	a	a	NOUN
app-795	166	8	)	)	PUNCT
app-795	166	9	is	be	AUX
app-795	166	10	another	another	DET
app-795	166	11	important	important	ADJ
app-795	166	12	autonomic	autonomic	ADJ
app-795	166	13	marker	marker	NOUN
app-795	166	14	.	.	PUNCT
app-795	167	1	as	as	ADP
app-795	167	2	a	a	DET
app-795	167	3	glycoprotein	glycoprotein	NOUN
app-795	167	4	,	,	PUNCT
app-795	167	5	it	it	PRON
app-795	167	6	reflects	reflect	VERB
app-795	167	7	changes	change	NOUN
app-795	167	8	in	in	ADP
app-795	167	9	the	the	DET
app-795	167	10	autonomic	autonomic	ADJ
app-795	167	11	nervous	nervous	ADJ
app-795	167	12	system	system	NOUN
app-795	167	13	and	and	CCONJ
app-795	167	14	is	be	AUX
app-795	167	15	sensitive	sensitive	ADJ
app-795	167	16	to	to	ADP
app-795	167	17	psychological	psychological	ADJ
app-795	167	18	stress	stress	NOUN
app-795	167	19	[	[	X
app-795	167	20	16	16	NUM
app-795	167	21	]	]	PUNCT
app-795	167	22	.	.	PUNCT
app-795	168	1	cg	cg	NOUN
app-795	168	2	-	-	PUNCT
app-795	168	3	a	a	NOUN
app-795	168	4	is	be	AUX
app-795	168	5	a	a	DET
app-795	168	6	precursor	precursor	NOUN
app-795	168	7	to	to	ADP
app-795	168	8	several	several	ADJ
app-795	168	9	peptides	peptide	NOUN
app-795	168	10	involved	involve	VERB
app-795	168	11	in	in	ADP
app-795	168	12	immune	immune	ADJ
app-795	168	13	regulation	regulation	NOUN
app-795	168	14	and	and	CCONJ
app-795	168	15	periodontal	periodontal	ADJ
app-795	168	16	inflammation	inflammation	NOUN
app-795	168	17	[	[	X
app-795	168	18	31	31	NUM
app-795	168	19	]	]	PUNCT
app-795	168	20	.	.	PUNCT
app-795	169	1	elevated	elevated	ADJ
app-795	169	2	concentrations	concentration	NOUN
app-795	169	3	of	of	ADP
app-795	169	4	cortisol	cortisol	NOUN
app-795	169	5	,	,	PUNCT
app-795	169	6	chromogranin	chromogranin	PROPN
app-795	169	7	a	a	DET
app-795	169	8	(	(	PUNCT
app-795	169	9	cg	cg	NOUN
app-795	169	10	-	-	PUNCT
app-795	169	11	a	a	NOUN
app-795	169	12	)	)	PUNCT
app-795	169	13	,	,	PUNCT
app-795	169	14	and	and	CCONJ
app-795	169	15	alpha	alpha	NOUN
app-795	169	16	-	-	NOUN
app-795	169	17	amylase	amylase	NOUN
app-795	169	18	in	in	ADP
app-795	169	19	saliva	saliva	NOUN
app-795	169	20	are	be	AUX
app-795	169	21	widely	widely	ADV
app-795	169	22	recognized	recognize	VERB
app-795	169	23	as	as	ADP
app-795	169	24	markers	marker	NOUN
app-795	169	25	of	of	ADP
app-795	169	26	heightened	heightened	ADJ
app-795	169	27	hypothalamic	hypothalamic	ADJ
app-795	169	28	-	-	PUNCT
app-795	169	29	pituitary	pituitary	ADJ
app-795	169	30	-	-	PUNCT
app-795	169	31	adrenal	adrenal	ADJ
app-795	169	32	(	(	PUNCT
app-795	169	33	hpa	hpa	NOUN
app-795	169	34	)	)	PUNCT
app-795	169	35	axis	axis	NOUN
app-795	169	36	and	and	CCONJ
app-795	169	37	sympathetic	sympathetic	ADJ
app-795	169	38	nervous	nervous	ADJ
app-795	169	39	system	system	NOUN
app-795	169	40	activity	activity	NOUN
app-795	169	41	.	.	PUNCT
app-795	170	1	in	in	ADP
app-795	170	2	parallel	parallel	NOUN
app-795	170	3	,	,	PUNCT
app-795	170	4	increased	increase	VERB
app-795	170	5	levels	level	NOUN
app-795	170	6	of	of	ADP
app-795	170	7	interleukin-6	interleukin-6	PROPN
app-795	170	8	(	(	PUNCT
app-795	170	9	il-6	il-6	NOUN
app-795	170	10	)	)	PUNCT
app-795	170	11	reflect	reflect	VERB
app-795	170	12	inflammatory	inflammatory	ADJ
app-795	170	13	responses	response	NOUN
app-795	170	14	that	that	PRON
app-795	170	15	often	often	ADV
app-795	170	16	accompany	accompany	VERB
app-795	170	17	both	both	PRON
app-795	170	18	psychological	psychological	ADJ
app-795	170	19	stress	stress	NOUN
app-795	170	20	and	and	CCONJ
app-795	170	21	oral	oral	ADJ
app-795	170	22	inflammatory	inflammatory	ADJ
app-795	170	23	diseases	disease	NOUN
app-795	170	24	.	.	PUNCT
app-795	171	1	conclusion	conclusion	NOUN
app-795	171	2	the	the	DET
app-795	171	3	intricate	intricate	ADJ
app-795	171	4	relationship	relationship	NOUN
app-795	171	5	between	between	ADP
app-795	171	6	anxiety	anxiety	NOUN
app-795	171	7	,	,	PUNCT
app-795	171	8	depression	depression	NOUN
app-795	171	9	,	,	PUNCT
app-795	171	10	and	and	CCONJ
app-795	171	11	periodontitis	periodontitis	NOUN
app-795	171	12	underscores	underscore	VERB
app-795	171	13	the	the	DET
app-795	171	14	necessity	necessity	NOUN
app-795	171	15	of	of	ADP
app-795	171	16	viewing	view	VERB
app-795	171	17	oral	oral	ADJ
app-795	171	18	and	and	CCONJ
app-795	171	19	mental	mental	ADJ
app-795	171	20	health	health	NOUN
app-795	171	21	as	as	ADP
app-795	171	22	interconnected	interconnected	ADJ
app-795	171	23	,	,	PUNCT
app-795	171	24	rather	rather	ADV
app-795	171	25	than	than	ADP
app-795	171	26	isolated	isolated	ADJ
app-795	171	27	domains	domain	NOUN
app-795	171	28	.	.	PUNCT
app-795	172	1	psychological	psychological	ADJ
app-795	172	2	stress	stress	NOUN
app-795	172	3	exerts	exert	VERB
app-795	172	4	influence	influence	NOUN
app-795	172	5	on	on	ADP
app-795	172	6	neuroendocrine	neuroendocrine	ADJ
app-795	172	7	regulation	regulation	NOUN
app-795	172	8	,	,	PUNCT
app-795	172	9	immune	immune	ADJ
app-795	172	10	system	system	NOUN
app-795	172	11	function	function	NOUN
app-795	172	12	,	,	PUNCT
app-795	172	13	and	and	CCONJ
app-795	172	14	behavioral	behavioral	ADJ
app-795	172	15	patterns	pattern	NOUN
app-795	172	16	,	,	PUNCT
app-795	172	17	each	each	PRON
app-795	172	18	of	of	ADP
app-795	172	19	which	which	PRON
app-795	172	20	heightens	heighten	VERB
app-795	172	21	vulnerability	vulnerability	NOUN
app-795	172	22	to	to	ADP
app-795	172	23	periodontal	periodontal	ADJ
app-795	172	24	disease	disease	NOUN
app-795	172	25	.	.	PUNCT
app-795	173	1	vitamin	vitamin	NOUN
app-795	173	2	d	d	NOUN
app-795	173	3	plays	play	VERB
app-795	173	4	a	a	DET
app-795	173	5	pivotal	pivotal	ADJ
app-795	173	6	role	role	NOUN
app-795	173	7	in	in	ADP
app-795	173	8	modulating	modulate	VERB
app-795	173	9	these	these	DET
app-795	173	10	biological	biological	ADJ
app-795	173	11	pathways	pathway	NOUN
app-795	173	12	,	,	PUNCT
app-795	173	13	thereby	thereby	ADV
app-795	173	14	impacting	impact	VERB
app-795	173	15	emotional	emotional	ADJ
app-795	173	16	well	well	ADV
app-795	173	17	-	-	PUNCT
app-795	173	18	being	being	NOUN
app-795	173	19	and	and	CCONJ
app-795	173	20	the	the	DET
app-795	173	21	integrity	integrity	NOUN
app-795	173	22	of	of	ADP
app-795	173	23	periodontal	periodontal	ADJ
app-795	173	24	tissues	tissue	NOUN
app-795	173	25	.	.	PUNCT
app-795	174	1	salivary	salivary	ADJ
app-795	174	2	biomarkers	biomarker	NOUN
app-795	174	3	provide	provide	VERB
app-795	174	4	a	a	DET
app-795	174	5	valuable	valuable	ADJ
app-795	174	6	,	,	PUNCT
app-795	174	7	non	non	ADJ
app-795	174	8	-	-	ADJ
app-795	174	9	invasive	invasive	ADJ
app-795	174	10	window	window	NOUN
app-795	174	11	into	into	ADP
app-795	174	12	these	these	DET
app-795	174	13	complex	complex	ADJ
app-795	174	14	mechanisms	mechanism	NOUN
app-795	174	15	.	.	PUNCT
app-795	175	1	this	this	DET
app-795	175	2	medium	medium	NOUN
app-795	175	3	allows	allow	VERB
app-795	175	4	clinicians	clinician	NOUN
app-795	175	5	to	to	PART
app-795	175	6	assess	assess	VERB
app-795	175	7	underlying	underlie	VERB
app-795	175	8	physiological	physiological	ADJ
app-795	175	9	changes	change	NOUN
app-795	175	10	noninvasively	noninvasively	ADV
app-795	175	11	before	before	SCONJ
app-795	175	12	visible	visible	ADJ
app-795	175	13	symptoms	symptom	NOUN
app-795	175	14	appear	appear	VERB
app-795	175	15	,	,	PUNCT
app-795	175	16	facilitating	facilitate	VERB
app-795	175	17	earlier	early	ADJ
app-795	175	18	intervention	intervention	NOUN
app-795	175	19	.	.	PUNCT
app-795	176	1	recognizing	recognize	VERB
app-795	176	2	these	these	DET
app-795	176	3	shared	share	VERB
app-795	176	4	mechanisms	mechanism	NOUN
app-795	176	5	advocates	advocate	VERB
app-795	176	6	an	an	DET
app-795	176	7	integrated	integrate	VERB
app-795	176	8	health	health	NOUN
app-795	176	9	care	care	NOUN
app-795	176	10	approachone	approachone	NOUN
app-795	176	11	that	that	PRON
app-795	176	12	bridges	bridge	VERB
app-795	176	13	mental	mental	ADJ
app-795	176	14	and	and	CCONJ
app-795	176	15	oral	oral	ADJ
app-795	176	16	health	health	NOUN
app-795	176	17	strategies	strategy	NOUN
app-795	176	18	for	for	ADP
app-795	176	19	prevention	prevention	NOUN
app-795	176	20	,	,	PUNCT
app-795	176	21	early	early	ADJ
app-795	176	22	detection	detection	NOUN
app-795	176	23	,	,	PUNCT
app-795	176	24	and	and	CCONJ
app-795	176	25	effective	effective	ADJ
app-795	176	26	treatment	treatment	NOUN
app-795	176	27	.	.	PUNCT
app-795	177	1	this	this	DET
app-795	177	2	proactive	proactive	ADJ
app-795	177	3	approach	approach	NOUN
app-795	177	4	not	not	PART
app-795	177	5	only	only	ADV
app-795	177	6	holds	hold	VERB
app-795	177	7	promise	promise	NOUN
app-795	177	8	for	for	ADP
app-795	177	9	improving	improve	VERB
app-795	177	10	patient	patient	ADJ
app-795	177	11	outcomes	outcome	NOUN
app-795	177	12	but	but	CCONJ
app-795	177	13	also	also	ADV
app-795	177	14	has	have	VERB
app-795	177	15	the	the	DET
app-795	177	16	potential	potential	NOUN
app-795	177	17	to	to	PART
app-795	177	18	alleviate	alleviate	VERB
app-795	177	19	long	long	ADJ
app-795	177	20	-	-	PUNCT
app-795	177	21	term	term	NOUN
app-795	177	22	healthcare	healthcare	NOUN
app-795	177	23	costs	cost	NOUN
app-795	177	24	and	and	CCONJ
app-795	177	25	resource	resource	NOUN
app-795	177	26	burdens	burden	NOUN
app-795	177	27	associated	associate	VERB
app-795	177	28	with	with	ADP
app-795	177	29	advanced	advanced	ADJ
app-795	177	30	disease	disease	NOUN
app-795	177	31	states	state	NOUN
app-795	177	32	.	.	PUNCT
app-795	178	1	figure	figure	NOUN
app-795	178	2	1	1	NUM
app-795	178	3	.	.	PUNCT
app-795	178	4	reduced	reduce	VERB
app-795	178	5	salivary	salivary	ADJ
app-795	178	6	1,25(oh)₂d₃	1,25(oh)₂d₃	NUM
app-795	178	7	and	and	CCONJ
app-795	178	8	elevated	elevated	ADJ
app-795	178	9	levels	level	NOUN
app-795	178	10	of	of	ADP
app-795	178	11	cortisol	cortisol	NOUN
app-795	178	12	,	,	PUNCT
app-795	178	13	il-6	il-6	NOUN
app-795	178	14	,	,	PUNCT
app-795	178	15	cg	cg	NOUN
app-795	178	16	-	-	PUNCT
app-795	178	17	a	a	NOUN
app-795	178	18	,	,	PUNCT
app-795	178	19	and	and	CCONJ
app-795	178	20	saa	saa	PROPN
app-795	178	21	disrupt	disrupt	PROPN
app-795	178	22	neuro	neuro	PROPN
app-795	178	23	-	-	PUNCT
app-795	178	24	endocrine	endocrine	NOUN
app-795	178	25	–	–	PUNCT
app-795	178	26	immune	immune	ADJ
app-795	178	27	homeostasis	homeostasis	NOUN
app-795	178	28	,	,	PUNCT
app-795	178	29	promote	promote	VERB
app-795	178	30	hyperactivity	hyperactivity	NOUN
app-795	178	31	of	of	ADP
app-795	178	32	the	the	DET
app-795	178	33	hpa	hpa	NOUN
app-795	178	34	axis	axis	NOUN
app-795	178	35	and	and	CCONJ
app-795	178	36	sympathetic	sympathetic	ADJ
app-795	178	37	nervous	nervous	ADJ
app-795	178	38	system	system	NOUN
app-795	178	39	,	,	PUNCT
app-795	178	40	and	and	CCONJ
app-795	178	41	shift	shift	VERB
app-795	178	42	immunity	immunity	NOUN
app-795	178	43	towards	towards	ADP
app-795	178	44	a	a	DET
app-795	178	45	destructive	destructive	ADJ
app-795	178	46	phase	phase	NOUN
app-795	178	47	,	,	PUNCT
app-795	178	48	thereby	thereby	ADV
app-795	178	49	increasing	increase	VERB
app-795	178	50	vulnerability	vulnerability	NOUN
app-795	178	51	to	to	ADP
app-795	178	52	anxiety	anxiety	NOUN
app-795	178	53	,	,	PUNCT
app-795	178	54	depression	depression	NOUN
app-795	178	55	,	,	PUNCT
app-795	178	56	and	and	CCONJ
app-795	178	57	periodontitis	periodontitis	NOUN
app-795	178	58	.	.	PUNCT
app-795	179	1	references	reference	NOUN
app-795	179	2	ali	ali	PROPN
app-795	179	3	m	m	PROPN
app-795	179	4	,	,	PUNCT
app-795	179	5	taj	taj	PROPN
app-795	179	6	y	y	PROPN
app-795	179	7	,	,	PUNCT
app-795	179	8	tanwir	tanwir	NOUN
app-795	179	9	f	f	NOUN
app-795	179	10	,	,	PUNCT
app-795	179	11	et	et	PROPN
app-795	179	12	al	al	PROPN
app-795	179	13	.	.	PROPN
app-795	179	14	mmp-8	mmp-8	PROPN
app-795	179	15	,	,	PUNCT
app-795	179	16	il-6	il-6	PRON
app-795	179	17	,	,	PUNCT
app-795	179	18	il-1β	il-1β	ADJ
app-795	179	19	as	as	ADP
app-795	179	20	biomarkers	biomarker	NOUN
app-795	179	21	.	.	PUNCT
app-795	180	1	age	age	NOUN
app-795	180	2	.	.	PUNCT
app-795	181	1	2025;15:39	2025;15:39	NUM
app-795	181	2	5.10.29271	5.10.29271	NUM
app-795	181	3	/	/	SYM
app-795	181	4	jcpsp.2025.07.825	jcpsp.2025.07.825	PROPN
app-795	181	5	ali	ali	PROPN
app-795	181	6	n	n	PROPN
app-795	181	7	,	,	PUNCT
app-795	181	8	nater	nater	PROPN
app-795	181	9	um	um	INTJ
app-795	181	10	.	.	PUNCT
app-795	181	11	salivary	salivary	PROPN
app-795	181	12	alpha	alpha	NOUN
app-795	181	13	-	-	PUNCT
app-795	181	14	amylase	amylase	NOUN
app-795	181	15	as	as	ADP
app-795	181	16	a	a	DET
app-795	181	17	stress	stress	NOUN
app-795	181	18	biomarker	biomarker	NOUN
app-795	181	19	.	.	PUNCT
app-795	182	1	int	int	PROPN
app-795	182	2	j	j	PROPN
app-795	182	3	behav	behav	PROPN
app-795	182	4	med	me	VERB
app-795	182	5	.	.	PUNCT
app-795	183	1	2020;27(3):337	2020;27(3):337	NUM
app-795	183	2	-	-	PUNCT
app-795	183	3	42.10.1007	42.10.1007	NOUN
app-795	183	4	/	/	SYM
app-795	183	5	s12529	s12529	NOUN
app-795	183	6	-	-	PUNCT
app-795	183	7	019	019	NUM
app-795	183	8	-	-	PUNCT
app-795	183	9	09843	09843	NUM
app-795	183	10	-	-	PUNCT
app-795	183	11	x.	x.	NOUN
app-795	183	12	al	al	PROPN
app-795	183	13	shaar	shaar	PROPN
app-795	183	14	a	a	PRON
app-795	183	15	,	,	PUNCT
app-795	183	16	hamadeh	hamadeh	PROPN
app-795	183	17	o	o	NOUN
app-795	183	18	,	,	PUNCT
app-795	183	19	ali	ali	PROPN
app-795	183	20	a.	a.	NOUN
app-795	183	21	saliva	saliva	NOUN
app-795	183	22	and	and	CCONJ
app-795	183	23	serum	serum	NOUN
app-795	183	24	biomarkers	biomarker	NOUN
app-795	183	25	.	.	PUNCT
app-795	184	1	medicine	medicine	NOUN
app-795	184	2	.	.	PUNCT
app-795	185	1	2024;103(52):e41072.10.1097	2024;103(52):e41072.10.1097	NUM
app-795	185	2	/	/	SYM
app-795	185	3	md.0000000000041072	md.0000000000041072	PROPN
app-795	185	4	.	.	PUNCT
app-795	185	5	antonoglou	antonoglou	PROPN
app-795	185	6	gn	gn	PROPN
app-795	185	7	,	,	PUNCT
app-795	185	8	et	et	PROPN
app-795	185	9	al	al	PROPN
app-795	185	10	.	.	PROPN
app-795	185	11	low	low	PROPN
app-795	185	12	serum	serum	PROPN
app-795	185	13	1,25(oh)2d	1,25(oh)2d	NUM
app-795	185	14	and	and	CCONJ
app-795	185	15	periodontitis	periodontitis	NOUN
app-795	185	16	.	.	PUNCT
app-795	186	1	j	j	PROPN
app-795	186	2	periodontal	periodontal	ADJ
app-795	186	3	res	re	NOUN
app-795	186	4	.	.	PUNCT
app-795	187	1	2015;50:274	2015;50:274	NOUN
app-795	187	2	-	-	SYM
app-795	187	3	80	80	NUM
app-795	187	4	.	.	PUNCT
app-795	188	1	ball	ball	PROPN
app-795	188	2	j	j	PROPN
app-795	188	3	,	,	PUNCT
app-795	188	4	darby	darby	PROPN
app-795	188	5	i.	i.	PROPN
app-795	188	6	mental	mental	PROPN
app-795	188	7	health	health	PROPN
app-795	188	8	and	and	CCONJ
app-795	188	9	periodontal	periodontal	ADJ
app-795	188	10	and	and	CCONJ
app-795	188	11	peri	peri	ADJ
app-795	188	12	-	-	PUNCT
app-795	188	13	implant	implant	ADJ
app-795	188	14	diseases	disease	NOUN
app-795	188	15	.	.	PUNCT
app-795	189	1	periodontol	periodontol	NOUN
app-795	189	2	2000	2000	NUM
app-795	189	3	.	.	PUNCT
app-795	190	1	2022;90(1):106	2022;90(1):106	NUM
app-795	190	2	-	-	PUNCT
app-795	190	3	24.10.1111	24.10.1111	NUM
app-795	190	4	/	/	SYM
app-795	190	5	prd.12452	prd.12452	NOUN
app-795	190	6	becerra	becerra	PROPN
app-795	190	7	-	-	PUNCT
app-795	190	8	ruiz	ruiz	PROPN
app-795	190	9	js	js	PROPN
app-795	190	10	,	,	PUNCT
app-795	190	11	guerrero	guerrero	NOUN
app-795	190	12	-	-	PUNCT
app-795	190	13	velázquez	velázquez	NOUN
app-795	190	14	c	c	NOUN
app-795	190	15	,	,	PUNCT
app-795	190	16	martínez	martínez	NOUN
app-795	190	17	-	-	PUNCT
app-795	190	18	esquivias	esquivias	PROPN
app-795	190	19	f	f	NOUN
app-795	190	20	,	,	PUNCT
app-795	190	21	et	et	PROPN
app-795	190	22	al	al	PROPN
app-795	190	23	.	.	PROPN
app-795	190	24	innate	innate	ADJ
app-795	190	25	and	and	CCONJ
app-795	190	26	adaptive	adaptive	ADJ
app-795	190	27	immunity	immunity	NOUN
app-795	190	28	…	…	PUNCT
app-795	190	29	oral	oral	ADJ
app-795	190	30	dis	dis	NOUN
app-795	190	31	.	.	PUNCT
app-795	191	1	2022;28(6):1441	2022;28(6):1441	NUM
app-795	191	2	-	-	SYM
app-795	191	3	7.10.1111	7.10.1111	NUM
app-795	191	4	/	/	SYM
app-795	191	5	odi.13884	odi.13884	VERB
app-795	191	6	charoenngam	charoenngam	NOUN
app-795	191	7	n	n	CCONJ
app-795	191	8	,	,	PUNCT
app-795	191	9	shirvani	shirvani	PROPN
app-795	191	10	a	a	PRON
app-795	191	11	,	,	PUNCT
app-795	191	12	holick	holick	NOUN
app-795	191	13	mf	mf	X
app-795	191	14	.	.	PROPN
app-795	191	15	vitamin	vitamin	NOUN
app-795	191	16	d	d	NOUN
app-795	191	17	for	for	ADP
app-795	191	18	skeletal	skeletal	ADJ
app-795	191	19	and	and	CCONJ
app-795	191	20	non	non	ADJ
app-795	191	21	-	-	ADJ
app-795	191	22	skeletal	skeletal	ADJ
app-795	191	23	health	health	NOUN
app-795	191	24	.	.	PUNCT
app-795	192	1	j	j	PROPN
app-795	192	2	clin	clin	PROPN
app-795	192	3	orthop	orthop	PROPN
app-795	192	4	trauma	trauma	NOUN
app-795	192	5	.	.	PUNCT
app-795	193	1	2019;10(6):1082	2019;10(6):1082	PROPN
app-795	193	2	-	-	PUNCT
app-795	193	3	93.10.1016	93.10.1016	PROPN
app-795	193	4	/	/	SYM
app-795	193	5	j.jcot.2019.07.004	j.jcot.2019.07.004	PROPN
app-795	193	6	.	.	PUNCT
app-795	194	1	chung	chung	PROPN
app-795	194	2	c	c	PROPN
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app-795	194	5	p	p	X
app-795	194	6	,	,	PUNCT
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app-795	194	9	,	,	PUNCT
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app-795	194	12	,	,	PUNCT
app-795	194	13	jo	jo	PROPN
app-795	195	1	ek	ek	PROPN
app-795	195	2	.	.	PUNCT
app-795	196	1	vitamin	vitamin	PROPN
app-795	196	2	d	d	NOUN
app-795	196	3	-	-	ADJ
app-795	196	4	cathelicidin	cathelicidin	ADJ
app-795	196	5	axis	axis	ADJ
app-795	196	6	…	…	SYM
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app-795	196	9	.	.	PUNCT
app-795	197	1	2020;20(2):e12	2020;20(2):e12	NUM
app-795	197	2	.	.	PUNCT
app-795	197	3	10.4110	10.4110	NUM
app-795	197	4	/	/	SYM
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app-795	197	8	,	,	PUNCT
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app-795	197	14	,	,	PUNCT
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app-795	197	19	in	in	ADP
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app-795	197	21	.	.	PUNCT
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app-795	198	2	oral	oral	ADJ
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app-795	198	6	.	.	PUNCT
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app-795	199	2	-	-	SYM
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app-795	199	4	/	/	SYM
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app-795	199	6	.	.	PUNCT
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app-795	199	9	,	,	PUNCT
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app-795	199	12	,	,	PUNCT
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app-795	199	14	k	k	PROPN
app-795	199	15	,	,	PUNCT
app-795	199	16	et	et	PROPN
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app-795	199	18	.	.	PROPN
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app-795	200	3	as	as	ADP
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app-795	200	6	.	.	PUNCT
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app-795	201	4	.	.	PUNCT
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app-795	202	2	/	/	SYM
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app-795	202	4	gunepin	gunepin	PROPN
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app-795	202	6	,	,	PUNCT
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app-795	202	8	f	f	PROPN
app-795	202	9	,	,	PUNCT
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app-795	202	11	m	m	PROPN
app-795	202	12	,	,	PUNCT
app-795	202	13	et	et	PROPN
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app-795	202	15	.	.	PROPN
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app-795	202	17	stress	stress	NOUN
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app-795	202	19	periodontal	periodontal	ADJ
app-795	202	20	health	health	NOUN
app-795	202	21	.	.	PUNCT
app-795	203	1	j	j	PROPN
app-795	203	2	oral	oral	ADJ
app-795	203	3	med	med	ADJ
app-795	203	4	oral	oral	ADJ
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app-795	203	6	.	.	PUNCT
app-795	204	1	2018;24(1):44	2018;24(1):44	X
app-795	204	2	-	-	SYM
app-795	204	3	50.10.1051	50.10.1051	NUM
app-795	204	4	/	/	SYM
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app-795	204	7	s.	s.	PROPN
app-795	204	8	chronic	chronic	PROPN
app-795	204	9	stress	stress	NOUN
app-795	204	10	,	,	PUNCT
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app-795	204	12	,	,	PUNCT
app-795	204	13	and	and	CCONJ
app-795	204	14	depression	depression	NOUN
app-795	204	15	…	…	SYM
app-795	204	16	front	front	ADJ
app-795	204	17	psychiatry	psychiatry	NOUN
app-795	204	18	.	.	PUNCT
app-795	205	1	2023;14:1130989.https://doi.org/10.3389	2023;14:1130989.https://doi.org/10.3389	X
app-795	205	2	/	/	SYM
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app-795	206	2	,	,	PUNCT
app-795	206	3	fathima	fathima	PROPN
app-795	206	4	s	s	PROPN
app-795	206	5	,	,	PUNCT
app-795	206	6	hisham	hisham	PROPN
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app-795	206	8	,	,	PUNCT
app-795	206	9	et	et	PROPN
app-795	206	10	al	al	PROPN
app-795	206	11	.	.	PROPN
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app-795	207	3	-	-	PUNCT
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app-795	207	5	in	in	ADP
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app-795	207	7	.	.	PUNCT
app-795	208	1	curr	curr	PROPN
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app-795	208	5	.	.	PUNCT
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app-795	209	2	-	-	SYM
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app-795	210	1	hingorjo	hingorjo	PROPN
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app-795	210	3	,	,	PUNCT
app-795	210	4	owais	owais	PROPN
app-795	210	5	m	m	PROPN
app-795	210	6	,	,	PUNCT
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app-795	210	8	s	s	PART
app-795	210	9	,	,	PUNCT
app-795	210	10	et	et	PROPN
app-795	210	11	al	al	PROPN
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app-795	210	14	and	and	CCONJ
app-795	210	15	salivary	salivary	ADJ
app-795	210	16	cortisol	cortisol	NOUN
app-795	210	17	in	in	ADP
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app-795	210	19	.	.	PUNCT
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app-795	211	4	.	.	PUNCT
app-795	212	1	2025;25:276.10.1186	2025;25:276.10.1186	X
app-795	212	2	/	/	SYM
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app-795	212	4	-	-	PUNCT
app-795	212	5	024	024	NUM
app-795	212	6	-	-	PUNCT
app-795	212	7	05017	05017	NUM
app-795	212	8	-	-	PUNCT
app-795	212	9	8	8	NUM
app-795	212	10	.	.	PUNCT
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app-795	213	3	,	,	PUNCT
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app-795	213	6	,	,	PUNCT
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app-795	213	9	,	,	PUNCT
app-795	213	10	et	et	PROPN
app-795	213	11	al	al	PROPN
app-795	213	12	.	.	PUNCT
app-795	214	1	dietary	dietary	ADJ
app-795	214	2	supplements	supplement	NOUN
app-795	214	3	in	in	ADP
app-795	214	4	depression	depression	NOUN
app-795	214	5	.	.	PUNCT
app-795	215	1	pharmacopsychiatry	pharmacopsychiatry	NOUN
app-795	215	2	.	.	PUNCT
app-795	216	1	2019;52(6):261	2019;52(6):261	NUM
app-795	216	2	-	-	PUNCT
app-795	216	3	79.10.1055	79.10.1055	NUM
app-795	216	4	/	/	SYM
app-795	216	5	a-0942	a-0942	NOUN
app-795	216	6	-	-	PUNCT
app-795	216	7	1875	1875	NUM
app-795	216	8	.	.	PUNCT
app-795	217	1	küchler	küchler	PROPN
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app-795	217	3	,	,	PUNCT
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app-795	217	6	,	,	PUNCT
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app-795	217	9	,	,	PUNCT
app-795	217	10	et	et	PROPN
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app-795	217	12	.	.	PUNCT
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app-795	218	2	d	d	NOUN
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app-795	218	4	in	in	ADP
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app-795	218	8	.	.	PUNCT
app-795	219	1	bmc	bmc	ADJ
app-795	219	2	oral	oral	ADJ
app-795	219	3	health	health	NOUN
app-795	219	4	.	.	PUNCT
app-795	220	1	2021;21:386.https://doi.org/10.1186	2021;21:386.https://doi.org/10.1186	NUM
app-795	220	2	/	/	SYM
app-795	220	3	s12903	s12903	NOUN
app-795	220	4	-	-	PUNCT
app-795	220	5	02101740	02101740	NUM
app-795	220	6	-	-	PUNCT
app-795	220	7	8	8	NUM
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app-795	220	10	,	,	PUNCT
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app-795	220	13	,	,	PUNCT
app-795	220	14	hou	hou	PROPN
app-795	220	15	j.	j.	PROPN
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app-795	220	17	d	d	PROPN
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app-795	220	19	in	in	ADP
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app-795	220	21	fibroblasts	fibroblast	NOUN
app-795	220	22	.	.	PUNCT
app-795	221	1	plos	plos	PROPN
app-795	221	2	one	one	NUM
app-795	221	3	.	.	PUNCT
app-795	222	1	2012;7(6):e39878	2012;7(6):e39878	X
app-795	222	2	.	.	PUNCT
app-795	223	1	mirzaei	mirzaei	PROPN
app-795	223	2	m	m	PROPN
app-795	223	3	,	,	PUNCT
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app-795	223	5	sm	sm	PROPN
app-795	223	6	,	,	PUNCT
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app-795	223	9	,	,	PUNCT
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app-795	223	13	of	of	ADP
app-795	223	14	depression	depression	NOUN
app-795	223	15	,	,	PUNCT
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app-795	223	17	and	and	CCONJ
app-795	223	18	stress	stress	NOUN
app-795	223	19	among	among	ADP
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app-795	223	21	population	population	NOUN
app-795	223	22	:	:	PUNCT
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app-795	223	24	of	of	ADP
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app-795	224	4	.	.	PUNCT
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app-795	225	2	.	.	PUNCT
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app-795	226	3	,	,	PUNCT
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app-795	226	5	a	a	PRON
app-795	226	6	,	,	PUNCT
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app-795	226	9	,	,	PUNCT
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app-795	226	11	j.	j.	PROPN
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app-795	226	13	ulcerative	ulcerative	ADJ
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app-795	226	15	.	.	PUNCT
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app-795	228	2	-	-	PUNCT
app-795	228	3	500.10.4103	500.10.4103	NUM
app-795	228	4	/	/	SYM
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app-795	228	6	miller	miller	PROPN
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app-795	228	8	.	.	PUNCT
app-795	229	1	inflammation	inflammation	NOUN
app-795	229	2	and	and	CCONJ
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app-795	229	4	.	.	PUNCT
app-795	230	1	psychiatric	psychiatric	ADJ
app-795	230	2	times	time	NOUN
app-795	230	3	.	.	PUNCT
app-795	231	1	2018;35(4	2018;35(4	NUM
app-795	231	2	)	)	PUNCT
app-795	231	3	.	.	PUNCT
app-795	232	1	nih	nih	PROPN
app-795	232	2	office	office	PROPN
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app-795	232	5	supplements	supplement	NOUN
app-795	232	6	.	.	PUNCT
app-795	233	1	vitamin	vitamin	NOUN
app-795	233	2	d	d	PRON
app-795	233	3	fact	fact	NOUN
app-795	233	4	sheet	sheet	NOUN
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app-795	233	7	professionals	professional	NOUN
app-795	233	8	.	.	PUNCT
app-795	234	1	2017	2017	NUM
app-795	234	2	.	.	PUNCT
app-795	235	1	o’donovan	o’donovan	NOUN
app-795	235	2	a	a	PRON
app-795	235	3	,	,	PUNCT
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app-795	235	9	,	,	PUNCT
app-795	235	10	et	et	PROPN
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app-795	235	12	.	.	PUNCT
app-795	235	13	anxiety	anxiety	NOUN
app-795	235	14	,	,	PUNCT
app-795	235	15	cortisol	cortisol	NOUN
app-795	235	16	and	and	CCONJ
app-795	235	17	il-6	il-6	NOUN
app-795	235	18	.	.	PUNCT
app-795	236	1	brain	brain	PROPN
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app-795	236	4	.	.	PUNCT
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app-795	237	2	-	-	SYM
app-795	237	3	7.10.1016	7.10.1016	NUM
app-795	237	4	/	/	SYM
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app-795	237	14	,	,	PUNCT
app-795	237	15	et	et	PROPN
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app-795	237	17	.	.	PROPN
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app-795	237	23	.	.	PUNCT
app-795	238	1	j	j	PROPN
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app-795	238	6	.	.	PUNCT
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app-795	239	2	-	-	PUNCT
app-795	239	3	41.10.1515	41.10.1515	NUM
app-795	239	4	/	/	SYM
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app-795	239	6	-	-	PUNCT
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app-795	239	8	.	.	PUNCT
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app-795	240	11	al	al	PROPN
app-795	240	12	.	.	PUNCT
app-795	241	1	vitamin	vitamin	NOUN
app-795	241	2	d	d	NOUN
app-795	241	3	binding	bind	VERB
app-795	241	4	protein	protein	NOUN
app-795	241	5	in	in	ADP
app-795	241	6	periodontitis	periodontitis	NOUN
app-795	241	7	.	.	PUNCT
app-795	242	1	pak	pak	PROPN
app-795	242	2	j	j	PROPN
app-795	242	3	med	med	PROPN
app-795	242	4	sci	sci	PROPN
app-795	242	5	.	.	PUNCT
app-795	243	1	2019;35(3):847.https://doi.org/10.12669	2019;35(3):847.https://doi.org/10.12669	NUM
app-795	243	2	/	/	SYM
app-795	243	3	pjms.35.3.482	pjms.35.3.482	NUM
app-795	243	4	rafique	rafique	PROPN
app-795	243	5	s	s	PROPN
app-795	243	6	,	,	PUNCT
app-795	243	7	ahmed	ahmed	PROPN
app-795	243	8	s	s	PROPN
app-795	243	9	,	,	PUNCT
app-795	243	10	noushad	noushad	ADJ
app-795	243	11	s.	s.	PROPN
app-795	243	12	salivary	salivary	VERB
app-795	243	13	vitamin	vitamin	PROPN
app-795	243	14	d	d	PROPN
app-795	243	15	&	&	CCONJ
app-795	243	16	cortisol	cortisol	PROPN
app-795	243	17	…	…	SYM
app-795	243	18	steroids	steroid	NOUN
app-795	243	19	.	.	PUNCT
app-795	244	1	2025:109674.10.1016	2025:109674.10.1016	NUM
app-795	244	2	/	/	SYM
app-795	244	3	j.steroids.2025.109674	j.steroids.2025.109674	NOUN
app-795	244	4	.	.	PUNCT
app-795	245	1	santos	santos	PROPN
app-795	245	2	sv	sv	PROPN
app-795	245	3	,	,	PUNCT
app-795	245	4	silva	silva	PROPN
app-795	245	5	la	la	PROPN
app-795	245	6	,	,	PUNCT
app-795	245	7	terra	terra	NOUN
app-795	245	8	fd	fd	PROPN
app-795	245	9	,	,	PUNCT
app-795	245	10	et	et	PROPN
app-795	245	11	al	al	PROPN
app-795	245	12	.	.	PROPN
app-795	245	13	salivary	salivary	PROPN
app-795	245	14	alpha	alpha	NOUN
app-795	245	15	-	-	PUNCT
app-795	245	16	amylase	amylase	NOUN
app-795	245	17	and	and	CCONJ
app-795	245	18	stress	stress	NOUN
app-795	245	19	.	.	PUNCT
app-795	246	1	rev	rev	AUX
app-795	246	2	lat	lat	PROPN
app-795	246	3	am	be	AUX
app-795	246	4	enfermagem	enfermagem	NOUN
app-795	246	5	.	.	PUNCT
app-795	247	1	2021;29	2021;29	NUM
app-795	247	2	:	:	PUNCT
app-795	247	3	e3468.10.1590/1518	e3468.10.1590/1518	PROPN
app-795	247	4	-	-	PUNCT
app-795	247	5	8345.4859.3468	8345.4859.3468	PROPN
app-795	247	6	.	.	PUNCT
app-795	248	1	soysal	soysal	PROPN
app-795	248	2	f	f	PROPN
app-795	248	3	,	,	PUNCT
app-795	248	4	isler	isler	PROPN
app-795	248	5	sc	sc	PROPN
app-795	248	6	,	,	PUNCT
app-795	248	7	guney	guney	PROPN
app-795	248	8	z	z	PROPN
app-795	248	9	,	,	PUNCT
app-795	248	10	et	et	PROPN
app-795	248	11	al	al	PROPN
app-795	248	12	.	.	PROPN
app-795	249	1	salivary	salivary	PROPN
app-795	249	2	chromogranin	chromogranin	PROPN
app-795	249	3	a	a	PRON
app-795	249	4	and	and	CCONJ
app-795	249	5	periodontal	periodontal	ADJ
app-795	249	6	health	health	NOUN
app-795	249	7	.	.	PUNCT
app-795	250	1	bmc	bmc	PROPN
app-795	250	2	oral	oral	ADJ
app-795	250	3	health	health	NOUN
app-795	250	4	.	.	PUNCT
app-795	251	1	2025;25:1536.https://doi.org/10.1186	2025;25:1536.https://doi.org/10.1186	NUM
app-795	251	2	/	/	SYM
app-795	251	3	s12903	s12903	NOUN
app-795	251	4	-	-	PUNCT
app-795	251	5	025	025	NUM
app-795	251	6	-	-	PUNCT
app-795	251	7	06912	06912	NUM
app-795	251	8	-	-	PUNCT
app-795	251	9	4	4	NUM
app-795	251	10	tang	tang	NOUN
app-795	251	11	q	q	NOUN
app-795	251	12	,	,	PUNCT
app-795	251	13	xu	xu	PROPN
app-795	251	14	w	w	PROPN
app-795	251	15	,	,	PUNCT
app-795	251	16	zhang	zhang	PROPN
app-795	251	17	f	f	PROPN
app-795	251	18	,	,	PUNCT
app-795	251	19	et	et	PROPN
app-795	251	20	al	al	PROPN
app-795	251	21	.	.	PROPN
app-795	251	22	interdisciplinary	interdisciplinary	ADJ
app-795	251	23	research	research	NOUN
app-795	251	24	on	on	ADP
app-795	251	25	periodontitis	periodontitis	NOUN
app-795	251	26	and	and	CCONJ
app-795	251	27	depression	depression	NOUN
app-795	251	28	.	.	PUNCT
app-795	252	1	front	front	ADJ
app-795	252	2	oral	oral	ADJ
app-795	252	3	health	health	NOUN
app-795	252	4	.	.	PUNCT
app-795	253	1	2025;6:1588737.https://doi.org/10.3389	2025;6:1588737.https://doi.org/10.3389	NUM
app-795	253	2	/	/	SYM
app-795	253	3	froh.2025.1588737	froh.2025.1588737	ADJ
app-795	253	4	walther	walther	NOUN
app-795	253	5	c	c	NOUN
app-795	253	6	,	,	PUNCT
app-795	253	7	lieske	lieske	PROPN
app-795	253	8	b	b	PROPN
app-795	253	9	,	,	PUNCT
app-795	253	10	borof	borof	NOUN
app-795	253	11	k	k	PROPN
app-795	253	12	,	,	PUNCT
app-795	253	13	et	et	PROPN
app-795	253	14	al	al	PROPN
app-795	253	15	.	.	PROPN
app-795	253	16	periodontitis	periodontitis	NOUN
app-795	253	17	and	and	CCONJ
app-795	253	18	depression	depression	NOUN
app-795	253	19	…	…	SYM
app-795	253	20	brain	brain	NOUN
app-795	253	21	behav	behav	NOUN
app-795	253	22	immun	immun	PROPN
app-795	253	23	.	.	PUNCT
app-795	254	1	2023;34:100689.10.1016	2023;34:100689.10.1016	NUM
app-795	254	2	/	/	SYM
app-795	254	3	j.bbih.2023.100689	j.bbih.2023.100689	NOUN
app-795	254	4	.	.	PUNCT
app-795	255	1	yaribeygi	yaribeygi	PROPN
app-795	255	2	h	h	PROPN
app-795	255	3	,	,	PUNCT
app-795	255	4	panahi	panahi	PROPN
app-795	255	5	y	y	PROPN
app-795	255	6	,	,	PUNCT
app-795	255	7	sahraei	sahraei	PROPN
app-795	255	8	h	h	PROPN
app-795	255	9	,	,	PUNCT
app-795	255	10	johnston	johnston	PROPN
app-795	255	11	tp	tp	PROPN
app-795	255	12	,	,	PUNCT
app-795	255	13	sahebkar	sahebkar	PROPN
app-795	255	14	a.	a.	NOUN
app-795	255	15	the	the	DET
app-795	255	16	impact	impact	NOUN
app-795	255	17	of	of	ADP
app-795	255	18	stress	stress	NOUN
app-795	255	19	on	on	ADP
app-795	255	20	body	body	NOUN
app-795	255	21	function	function	NOUN
app-795	255	22	:	:	PUNCT
app-795	255	23	a	a	DET
app-795	255	24	review	review	NOUN
app-795	255	25	.	.	PUNCT
app-795	256	1	excli	excli	PROPN
app-795	256	2	j.	j.	PROPN
app-795	256	3	2017;16:1057	2017;16:1057	PROPN
app-795	256	4	.	.	PUNCT
app-795	256	5	10.17179	10.17179	NUM
app-795	256	6	/	/	SYM
app-795	256	7	excli2017	excli2017	PROPN
app-795	256	8	-	-	PUNCT
app-795	256	9	480	480	NUM
app-795	256	10	zhang	zhang	PROPN
app-795	256	11	j	j	PROPN
app-795	256	12	,	,	PUNCT
app-795	256	13	lin	lin	PROPN
app-795	256	14	s	s	PROPN
app-795	256	15	,	,	PUNCT
app-795	256	16	luo	luo	PROPN
app-795	256	17	l	l	PROPN
app-795	256	18	,	,	PUNCT
app-795	256	19	et	et	PROPN
app-795	256	20	al	al	PROPN
app-795	256	21	.	.	PUNCT
app-795	257	1	psychological	psychological	ADJ
app-795	257	2	stress	stress	NOUN
app-795	257	3	:	:	PUNCT
app-795	257	4	neuroimmune	neuroimmune	NOUN
app-795	257	5	roles	role	NOUN
app-795	257	6	in	in	ADP
app-795	257	7	periodontal	periodontal	ADJ
app-795	257	8	disease	disease	NOUN
app-795	257	9	.	.	PUNCT
app-795	258	1	odontology	odontology	NOUN
app-795	258	2	.	.	PUNCT
app-795	259	1	2023;111(3):554	2023;111(3):554	NUM
app-795	259	2	-	-	SYM
app-795	259	3	64.10.1007	64.10.1007	NUM
app-795	259	4	/	/	SYM
app-795	259	5	s10266	s10266	PROPN
app-795	259	6	-	-	PUNCT
app-795	259	7	022	022	PROPN
app-795	259	8	-	-	PUNCT
app-795	259	9	00768	00768	NUM
app-795	259	10	-	-	PUNCT
app-795	259	11	8	8	NUM
app-795	259	12	.	.	PUNCT
app-795	259	13	image1.png	image1.png	PUNCT