# bib

id: cord-004680-u3cnsdl8
author: Lin, Z.
title: Typing of recent infectious bronchitis virus isolates causing nephritis in chicken
date: 1991
extension: .txt
mime: text/plain
words: 861
sentence: 34
flesch: 50
cache: cache/cord-004680-u3cnsdl8.txt
txt: txt/cord-004680-u3cnsdl8.txt
summary:
  Oligonucleotide fingerprinting of ribonucleic acids of infectious bronchitis virus strain Infectious avian nephrosis (ureamia) in Australia Occurrence and significance of infectious bronchitis virus variant strains in egg and broiler production in the Netherlands Serological comparisons of strains of infectious bronchitis virus using plaque-purified isolants Molecular epidemiology of infectious bronchitis virus in the Netherlands A new typing method for the avian infectious bronchitis virus using polymerase chain reaction and restriction enzyme fragment length polymorphism Etiology of an infectious nephritis-nephrosis syndrome of chickens Our present observation that the four new isolates used were different from the reference strains including current vaccine strains suggests that they were not derived from the live attenuated vaccine.


id: cord-004798-5budstbg
author: Takayama, N.
title: An improved method for titration of mouse hepatitis virus type 3 in a mouse cell culture
date: 1976
extension: .txt
mime: text/plain
words: 926
sentence: 31
flesch: 60
cache: cache/cord-004798-5budstbg.txt
txt: txt/cord-004798-5budstbg.txt
summary:
  Plaque formation by influenza viruses in the presence of trypsin The propagation of Coronaviruses in tissue-culture Plaque formation by a mouse hepatitis virus 1%eplication and plaque formation of mouse hepatitis virus (MttV-2) in mouse cell line DBT culture Observations on the growth of mouse hepatitis virus (MItV-3) in mouse macrophages Genetie recombination for antigenic markers of antigenieally differen$ strains of influenza B virus To ira.prove the sensitivity of the plaque assay we examined the effect of diethylaminoethyl-dextran (DEAE-D) on the plaque formation and plaque diameter of MHV3, as BRADBUllNE and TYRREL]5 had reported that DEAE-D added to overlay agar increased the plaque number of human coronavirus (2).


id: cord-279676-sk9xyd1r
author: Carossino, Mariano
title: Detection of SARS-CoV-2 by RNAscope(®)in situ hybridization and immunohistochemistry techniques
date: 2020-08-05
extension: .txt
mime: text/plain
words: 1655
sentence: 58
flesch: 34
cache: cache/cord-279676-sk9xyd1r.txt
txt: txt/cord-279676-sk9xyd1r.txt
summary:
  In situ detection of microRNA expression with RNAscope probes Dramatically improved RNA in situ hybridization signals using LNA-modified probes Detection of equine arteritis virus by two chromogenic RNA in situ hybridization assays (conventional and RNAscope(R)) and assessment of their performance in tissues from aborted equine fetuses Defining HIV and SIV reservoirs in lymphoid tissues RNA in situ hybridization for Epstein-barr virus and cytomegalovirus: comparison with in situ hybridization and immunohistochemistry Characterization of inducible transcription and translation-competent HIV-1 using the RNAscope ISH technology at a single-cell resolution. Thus, the objective of this study was to develop RNAscope ® ISH and IHC methods for the detection of SARS-CoV-2-specific antigen and RNA in infected cells that can be utilized for both research (e.g., studies involving experimentally and naturally infected animals) and diagnostic purposes.


id: cord-274780-fmnro0kw
author: Hoshino, Y.
title: Detection of astroviruses in feces of a cat with diarrhea
date: 1981
extension: .txt
mime: text/plain
words: 1372
sentence: 65
flesch: 45
cache: cache/cord-274780-fmnro0kw.txt
txt: txt/cord-274780-fmnro0kw.txt
summary:
  Bridging structures between virus particles were frequently seen (Fig. t, arrowheads) . A fecal sample was submitted for EM examination for viral particles.


id: cord-004808-6w9n03fy
author: Sekiguchi, K.
date: 1995
extension: .txt
mime: text/plain
words: 2069
sentence: 78
flesch: 50
cache: cache/cord-004808-6w9n03fy.txt
txt: txt/cord-004808-6w9n03fy.txt
title:
  Detection of equine arteritis virus (EAV) by polymerase chain reaction (PCR) and differentiation of EAV strains by restriction enzyme analysis of PCR products

summary:
  Molecular cloning and nucleotide sequencing ofthe 3'-terminal genomic RNA of the porcine reproductive and respiratory syndrome virus Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV Preparing for equine arteritis Detection and differentiation of EAV strains by PCR 149t Analysis ofgenetic variation among strains of equine arteritis virus Genomic variability among globally distributed isolates of equine arteritis virus Lactate dehydrogenase-elevating virns, equine arteritis virus, and simian hemorrhagic fever virus: a new group of positive-strand RNA viruses Molecular evolution of equine arteritis virus Sequence analysis of modified Bucyrus strain of equine arteritis virus Each of the PCR products amplified using the M 1-M 14 primer was digested with each of the four restriction enzymes; Xba I, Mva I, Mbo II, and Alu I. Digestion of PCR products from the Bucyrus, modified Bucyrus, live vaccine, and Wroclaw-2 strains with Xba I gave rise to fragments of about 174 bp and 57 bp (Fig. 4a) .


id: cord-004681-02wem2u3
author: Wada, R.
date: 1995
extension: .txt
mime: text/plain
words: 2045
sentence: 100
flesch: 51
cache: cache/cord-004681-02wem2u3.txt
txt: txt/cord-004681-02wem2u3.txt
title:
  Ultrastructure and immuno-cytochemistry of BHK-21 cells infected with a modified Bucyrus strain of equine arteritis virus

summary:
  key: cord-004681-02wem2u3 authors: Wada, R.; Fukunaga, Y.; Kondo, T.; Kanemaru, T. title: Ultrastructure and immuno-cytochemistry of BHK-21 cells infected with a modified Bucyrus strain of equine arteritis virus date: 1995 journal: Arch Virol DOI: 10.1007/bf01322744 sha: doc_id: 4681 cord_uid: 02wem2u3 Morphogenesis of a modified Bucyrus strain of equine arteritis virus (EAV) in BHK-21 cells was studied. Electron microscopic characterization of equine arteritis virus Equine arteritis virus: ferritin-tagging and determination of ribonucleic acid core Electron-microscopic studies of tissues ofhorses infected by equine arteritis virus


id: cord-004729-nmkilkcx
author: Reynolds, D. J.
date: 1979
extension: .txt
mime: text/plain
words: 2000
sentence: 81
flesch: 44
cache: cache/cord-004729-nmkilkcx.txt
txt: txt/cord-004729-nmkilkcx.txt
title:
  Virus isolation and serum antibody responses after infection of cats with transmissible gastroenteritis virus

summary:
  The medium was changed after 24 hours and 4 days later any viral eytopathic effect was recorded, the medium was removed and passaged in fresh APT/2 cultures and the eoverslips were stained to demonstrate virM antigen by indirect immunofluorescence, using paired sera from a gnotobiotic piglet before and after TGEV infection, followed by FITCconjugated rabbit anti-swine globulin (Nordic Immunological Laboratories, London). This evidence has been used to suggest that an antigenic relationship exists between TGEV and F I P virus.


id: cord-004831-lu62noak
author: Kempf, C.
date: 1987
extension: .txt
mime: text/plain
words: 1891
sentence: 86
flesch: 49
cache: cache/cord-004831-lu62noak.txt
txt: txt/cord-004831-lu62noak.txt
title:
  A novel method for the detection of early events in cell-cell fusion of Semliki Forest virus infected cells growing in monolayer cultures

summary:
  , Fusion of cell membranes is one of the most dramatic forms of membrane-membrane interactions (10) . key: cord-004831-lu62noak authors: Kempf, C.; Michel, M. R.; Kohler, U.; Koblet, H. title: A novel method for the detection of early events in cell-cell fusion of Semliki Forest virus infected cells growing in monolayer cultures date: 1987 journal: Arch Virol DOI: 10.1007/bf01310786 sha: doc_id: 4831 cord_uid: lu62noak Semliki Forest virus infected Aedes albopictus cells were used to investigate virus induced cell-cell fusion.


id: cord-252037-rj61mzqj
author: Gerna, G.
date: 2005-06-28
extension: .txt
mime: text/plain
words: 2210
sentence: 72
flesch: 33
cache: cache/cord-252037-rj61mzqj.txt
txt: txt/cord-252037-rj61mzqj.txt
title:
  Changing circulation rate of human metapneumovirus strains and types among hospitalized pediatric patients during three consecutive winter-spring seasons

summary:
  Statistical differences in the circulation rate of respiratory virus infections among the 3 consecutive seasons were determined by the chi square test. Within the aliquot of patients found positive for some respiratory virus, no difference in the circulation rate was observed for respiratory virus infections caused by influenzavirus B, hPIVs, hAdVs, hCoVs, and coinfections along the three years studied.


id: cord-004781-ajf9zig0
author: Ray, N. B.
title: Rabies viruses infect primary cultures of murine, feline, and human microglia and astrocytes
date: 2014-03-07
extension: .txt
mime: text/plain
words: 2343
sentence: 99
flesch: 39
cache: cache/cord-004781-ajf9zig0.txt
txt: txt/cord-004781-ajf9zig0.txt
summary:
  In the present study, as an initial step toward evaluation of the potential involvement of these glial cells in rabies virus infections, we have directly examined the ability of different rabies virus strains and isolates to infect and replicate in primary cultures of microglia and astrocytes. Natural anatomical relations and cellular interactions within the central nervous system are known to be important for rabies virus infection of The arrow identi®es a cell that was infected, but did not stain with GFAP glial cells in vivo


id: cord-004685-qote5nx2
author: Vassão, R. C.
date: 1994
extension: .txt
mime: text/plain
words: 2355
sentence: 73
flesch: 30
cache: cache/cord-004685-qote5nx2.txt
txt: txt/cord-004685-qote5nx2.txt
title:
  A genetic analysis of macrophage activation and specific antibodies in relation to the resistance of heterogeneous mouse populations to MHV3 infection

summary:
  The in vitro treatment with I F N gamma, which induced an anti-MHV3 effect only in resistant mouse macrophages, correlated with the in vivo resistance observed after MHV3 infection. The direct individual intrapopulation correlation between the induction of antiviral state in macrophages activated by IFN gamma and the resistance to the virus infection, showed that an antiviral state could be induced in resistant mouse macrophages, whereas in susceptible mouse macrophages no restriction of virus replication could be observed.


id: cord-004759-jozdnhgy
author: Snodgrass, D. R.
title: Pathogenesis of diarrhoea caused by astrovirus infections in lambs
date: 1979
extension: .txt
mime: text/plain
words: 2307
sentence: 115
flesch: 49
cache: cache/cord-004759-jozdnhgy.txt
txt: txt/cord-004759-jozdnhgy.txt
summary:
  g u t enterocytes of control lambs at 72 and 96 hours of age, but apical vacuoles were confined to the ileum of control lambs. In midgut of infected lambs, observations were consistently below those of the controls, fMling to a minimum of 1.2 units/g tissue at 23 hours p.i.


id: cord-004724-llex3yed
author: Dea, S. A.
title: Isolation of encephalomyocarditis virus among stillborn and post-weaning pigs in Quebec
date: 1991
extension: .txt
mime: text/plain
words: 2543
sentence: 116
flesch: 40
cache: cache/cord-004724-llex3yed.txt
txt: txt/cord-004724-llex3yed.txt
summary:
  Vero cells were found to be more sensitive than BHK-21 cells and pig cell lines for primary isolation of EMC virus. The Quebec EMC virus isolates were highly virulent for mice and were antigenically related to reference strain of EMC virus as demonstrated by indirect immunofluorescence, seroneutralization and Western immunoblotting.


id: cord-004765-7e4yu2do
author: Homberger, F. R.
title: Maternally-derived passive immunity to enterotropic mouse hepatitis virus
date: 1992
extension: .txt
mime: text/plain
words: 3096
sentence: 132
flesch: 53
cache: cache/cord-004765-7e4yu2do.txt
txt: txt/cord-004765-7e4yu2do.txt
summary:
  MHV-IgG, but not IgA or IgM, could be found in the serum of pups suckling immune dams. MHV serum IgG titers peaked at 14 days (Table2), when they reached levels higher than the ones found in their dams' sera collected immediately post partum.


id: cord-004693-1xglujqk
author: Chasey, D.
title: Morphogenesis of avian infectious bronchitis virus in primary chick kidney cells
date: 1976
extension: .txt
mime: text/plain
words: 3301
sentence: 162
flesch: 62
cache: cache/cord-004693-1xglujqk.txt
txt: txt/cord-004693-1xglujqk.txt
summary:
  Late in infection large numbers of virus particles were present, mainly in cytoplasmic vacuoles, and the majority were released by cell lysis. The budding mechanisms of virus particles in infected cells have been recorded in detail but little is known of the modes of entry and release although it has been generally reported that infection and release occur by viropexis and cell lysis respectively.


id: cord-004690-q38ogrem
author: Barthold, S. W.
title: Viremic dissemination of mouse hepatitis virus-JHM following intranasal inoculation of mice
date: 1992
extension: .txt
mime: text/plain
words: 3311
sentence: 124
flesch: 44
cache: cache/cord-004690-q38ogrem.txt
txt: txt/cord-004690-q38ogrem.txt
summary:
  The role of nasal epithelial cells as a primary target of lowvirulence virus Difference in response to mouse hepatitis virus among susceptible mouse strains Difference in sensitivity to interferon among mouse hepatitis viruses with high and low virulence for mice Factors involved in the age-dependent resistance of mice infected with low virulence mouse hepatitis virus The role of circulating interferon in the modifications of immune responsiveness by mouse hepatitis virus (MHV-3) The biology and pathogenesis of coronaviruses Purification of the 110-kilodalton glycoprotein receptor for MHV (MHV)-A59 from mouse liver and identification of a nonfunctional, homologous protein in MHV-resistant SJL/J mice T-lymphocyte.dependent difference in susceptibility between DDD and C3H mice to mouse hepatitis virus, MHV-3 This work was supported by grant RR02039 from the National Center for Research Resources, National Institutes of Health, Bethesda, Maryland. MHV replicated in nasal turbinates of both susceptible BALB and resistant SJL mice from days 1 through 5, but BALB mice had higher titers on days 1 and 2.


id: cord-003050-n25wnmq5
author: Nibert, Max L.
title: A barnavirus sequence mined from a transcriptome of the Antarctic pearlwort Colobanthus quitensis
date: 2018-03-07
extension: .txt
mime: text/plain
words: 3342
sentence: 128
flesch: 48
cache: cache/cord-003050-n25wnmq5.txt
txt: txt/cord-003050-n25wnmq5.txt
summary:
  See Table S4 for a summary of abbreviations and GenBank numbers The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis Ribosomal frameshifting and transcriptional slippage: from genetic steganography and cryptography to adventitious use Expression of the rice yellow mottle virus P1 protein in vitro and in vivo and its involvement in virus spread Mutational analysis of the slippery-sequence component of a coronavirus ribosomal frameshifting signal Fast and sensitive protein alignment using DIAMOND Multiple viral infections in Agaricus bisporus-characterisation of 18 unique RNA viruses and 8 ORFans identified by deep sequencing Organelle-like membrane compartmentalization of positive-strand RNA virus replication factories Genomic Resources Development Consortium Genomic Resources Notes SOSUI: classification and secondary structure prediction system for membrane proteins ModelFinder: fast model selection for accurate phylogenetic estimates An essential fifth coding ORF in the sobemoviruses Identification of diverse mycoviruses through metatranscriptomics characterization of the viromes of five major fungal plant pathogens Ultrafast approximation for phylogenetic bootstrap IQ-TREE: A fast and effective stochastic algorithm for estimating maximum likelihood phylogenies Virus taxonomy, ninth report of the International Committee on Taxonomy of Viruses Family Barnaviridae Identification of a subgenomic mRNA encoding the capsid protein of mushroom bacilliform virus, a single-stranded RNA mycovirus Mushroom bacilliform virus RNA: the initiation of translation at the 5´end of the genome and identification of the VPg Deduced protein sequences for the P3 (RdRp) region of P2+3 of barnaviruses (black) and sobemoviruses (gray) were aligned using MAFFT 7.3 (G-INS-i) and then subjected to maximum-likelihood phylogenetic analyses using Mod-elFinder, IQ-TREE, and UFBoot [10, 13, 14] as implemented with the Find best and apply option at https ://www.hiv.lanl.gov/conte nt/ seque nce/IQTRE E/iqtre e.html.


id: cord-254405-yc1q20fz
author: Jie, Tao
date: 2018-07-31
extension: .txt
mime: text/plain
words: 3456
sentence: 141
flesch: 51
cache: cache/cord-254405-yc1q20fz.txt
txt: txt/cord-254405-yc1q20fz.txt
title:
  Preparation and characterization of an attenuated porcine epidemic diarrhea virus strain by serial passaging

summary:
  The results should help our Shanghai Agriculture Applied Technology Development Program of China (No. T20170111), and the Youth Talent Development Plan of Shanghai Municipal Agricultural System of China Porcine epidemic diarrhea virus infection: etiology, epidemiology, pathogenesis and immunoprophylaxis New variant of porcine epidemic diarrhea virus, United States Investigation into the role of potentially contaminated feed as a source of the firstdetected outbreaks of porcine epidemic diarrhea in Canada Emergence of porcine epidemic diarrhea virus in southern Germany New porcine epidemic diarrhoea virus variant with a large deletion in the spike gene identified in domestic pigs New variants of porcine epidemic diarrhea virus, China Molecular characterization of the ORF3 and S1 genes of porcine epidemic diarrhea virus non S-INDEL strains in seven regions of China Complete genome sequence of PEDV from an outbreak in a vaccinated farm in Shandong Genome sequencing and analysis of a novel recombinant porcine epidemic diarrhea virus strain from Henan, China The identification and characterization of two novel epitopes on the nucleocapsid protein of the porcine epidemic diarrhea virus Epidemiology and vaccine of porcine epidemic diarrhea virus in China: a mini-review Comparative genomic analysis of classical and variant virulent parental/attenuated strains of porcine epidemic diarrhea virus Porcine epidemic diarrhea virus (PEDV) 3C-like protease-mediated nucleocapsid processing: a possible link to viral cell-culture adaptability Isolation and characterization of a variant porcine epidemic diarrhea virus in China Genetic variability and phylogeny of current Chinese porcine epidemic diarrhea virus strains based on spike, ORF3, and membrane genes Improvements in methods for calculating virus titer estimates from TCID50 and plaque assays Differentiation of a vero cell adapted porcine epidemic diarrhea virus from Korean field strains by restriction fragment length polymorphism analysis of ORF 3 Epidemiological survey on porcine diarrhea in swine breeding farms in China during 2013-2015 Molecular epidemiology of porcine epidemic diarrhea virus in China Environmental persistence of porcine coronaviruses in feed and feed ingredients Epidemiological survey of porcine epidemic diarrhea virus in 2014 Furthermore, we cultured the virus and screened for attenuated PEDV strains by analyzing the genovariations that occurred during passaging -confirming the results in animal experiments.


id: cord-006459-9kizif98
author: Deng, Guangcun
title: Acute respiratory distress syndrome induced by H9N2 virus in mice
date: 2009-11-28
extension: .txt
mime: text/plain
words: 3891
sentence: 184
flesch: 49
cache: cache/cord-006459-9kizif98.txt
txt: txt/cord-006459-9kizif98.txt
summary:
  The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia Molecular characterization of H9N2 influenza viruses: were they the donors of the ''internal'' genes of H5N1 viruses in Hong Kong? Characterization of the pathogenicity of members of the newly established H9N2 influenza virus lineages in Asia Infections and the inflammatory response in acute respiratory distress syndrome Sequence analysis of the hemagglutinin gene of H9N2 Korean avian influenza viruses and assessment of the pathogenic potential of isolate MS96 Evolution of H9N2 influenza viruses from domestic poultry in Mainland China Avian-to-human transmission of H9N2 subtype influenza A viruses: relationship between H9N2 and H5N1 human isolates Respiratory reovirus 1/L induction of intraluminal fibrosis, a model of bronchiolitis obliterans organizing pneumonia, is dependent on T lymphocytes H9N2 influenza A viruses from poultry in Asia have human virus-like receptor specificity The comparative pathology of severe acute respiratory syndrome and avian influenza A subtype H5N1-a review Role of p38 mitogenactivated protein kinase in a murine model of pulmonary inflammation Cocirculation of avian H9N2 and contemporary ''human'' H3N2 influenza A viruses in pigs in southeastern China: potential for genetic reassortment? Human infection with influenza H9N2 Prone position in acute respiratory distress syndrome Pulmonary and extrapulmonary acute respiratory distress syndrome are different Chemokines in acute respiratory distress syndrome Pigs are believed to serve as intermediate hosts for adaptation of avian influenza viruses that infect humans, and it has been shown that some of the H9N2 influenza viruses currently circulating in China have molecular features that allow them to preferentially bind to human a-2,6-NeuAcGal receptors [15, 24] .


id: cord-276617-chgjpg0v
author: Takano, Tomomi
date: 2008-11-30
extension: .txt
mime: text/plain
words: 3982
sentence: 163
flesch: 44
cache: cache/cord-276617-chgjpg0v.txt
txt: txt/cord-276617-chgjpg0v.txt
title:
  B-cell activation in cats with feline infectious peritonitis (FIP) by FIP-virus-induced B-cell differentiation/survival factors

summary:
  Moreover, increased levels of interleukin (IL)-6, a cytokine involved in the survival of B-cells and their differentiation into plasma cells, in ascites T. Takano Á N. Azuma Á Y. Hashida Á R. Satoh Á T. Hohdatsu (&) Laboratory of Veterinary Infectious Disease, School of Veterinary Medicine, Kitasato University, Towada, Aomori 034-8628, Japan e-mail: hohdatsu@vmas.kitasato-u.ac.jp and culture supernatant of peritoneal exudative cells (PEC) from FIP cats have been reported [8] . Thus, the number of plasma cells may increase in the peripheral blood of FIP cats.


id: cord-004738-vnz15x84
author: Chen, H. H.
date: 2006-03-27
extension: .txt
mime: text/plain
words: 4012
sentence: 123
flesch: 45
cache: cache/cord-004738-vnz15x84.txt
txt: txt/cord-004738-vnz15x84.txt
title:
  The rubella virus nonstructural protease recognizes itself via an internal sequence present upstream of the cleavage site for trans-activity

summary:
  Our analysis of RV protease substrates revealed that homologous polypeptides of N-terminal 475-and 309-residue length from the cleavage site, expressed from pRVS-827-1548 and pRVS-994-1548 (Fig. 2 , lanes 2 and 4, 80 and 67 kDa, respectively), were able to undergo cleavage when co-expressed along with RV protease (Fig. 2, lanes 1, 3, and 5 , 110 kDa) with an expected size of the N-terminal cleaved products of 55-and 37-kDa size (with additional Xpress epitope residues), respectively (Fig. 2, lanes 3 and 5) . However, besides the presence of the cleavage site, what the internal sequence requirements of the P200 and its intermediaries for RV protease trans-cleavage activity are, and how the cis-activity of P200 is regulated to maintain optimal negative RNA synthesis have not been identified.


id: cord-276630-qci7khki
author: Lima, William Gustavo
date: 2020-06-08
extension: .txt
mime: text/plain
words: 3740
sentence: 181
flesch: 46
cache: cache/cord-276630-qci7khki.txt
txt: txt/cord-276630-qci7khki.txt
title:
  The potential of drug repositioning as a short-term strategy for the control and treatment of COVID-19 (SARS-CoV-2): a systematic review

summary:
  Abidol and darunavir can effectively inhibit coronavirus Going global-Travel and the 2019 novel coronavirus Lopinavir/ritonavir: a review of its use in the management of HIV infection Screening of an FDA-approved compound library identifies four smallmolecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture Treatment With Lopinavir/Ritonavir or Interferon-β1b improves outcome of MERS-CoV infection in a nonhuman primate model of common marmoset Arbidol: a broad-spectrum antiviral compound that blocks viral fusion Arbidol as a broadspectrum antiviral: An update Antiviral activity of arbidol and its derivatives against the pathogen of severe acute respiratory syndrome in the cell cultures Therapeutic strategies to target the Ebola virus life cycle Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations The promising in vitro results of chloroquine and hydroxychloroquine have motivated the initiation of clinical studies of these substances ( Table 4) .


id: cord-004810-g0y7ied0
author: Lee, S. K.
title: S1 glycoprotein gene analysis of infectious bronchitis viruses isolated in Korea
date: 2003-11-13
extension: .txt
mime: text/plain
words: 3753
sentence: 157
flesch: 55
cache: cache/cord-004810-g0y7ied0.txt
txt: txt/cord-004810-g0y7ied0.txt
summary:
  Korean IBV isolates showed amino acid sequence similarity between 61.8% (K446-01 and K161-02) and 96.1% (K281-01 and K210-02) with each other and they showed amino acid sequence similarity between 42.9% (K161-02 and GA980470) and 96.5% (K203-02 and KB8523) compared to non-Korean IBV strains. The whole S 1 gene of representative 9 of Korean IBV isolates was sequenced to further characterize the isolates.


id: cord-258768-bjjfkfgg
author: McElligott, Susan
title: Detection and genetic characterization of canine parvoviruses and coronaviruses in southern Ireland
date: 2010-11-24
extension: .txt
mime: text/plain
words: 4386
sentence: 178
flesch: 48
cache: cache/cord-258768-bjjfkfgg.txt
txt: txt/cord-258768-bjjfkfgg.txt
summary:
  Infectious Diseases of the Dog and Cat (4 th ed) Isolation and immunisation studies of a canine parvo-like virus from dogs with hemorrhagic enteritis An update on canine coronaviruses: viral evolution and pathobiology The three-dimensional structure of canine parvovirus and its functional implications Canine parvoviruses and coronaviruses in southern Ireland 501 Evolution of canine parvovirus involved loss and gain of feline host range Rapid antigenic-type replacement and DNA evolution of canine parvovirus Evidence for evolution of canine parvovirus type 2 in Italy First detection of canine parvovirus type 2c in pups with haemorrhagic enteritis in Spain High rate of viral evolution associated with the emergence of carnivore parvovirus Canine parvovirus 2c infection in central Portugal Evidence for immunisation failure in vaccinated adult dogs infected with canine parvovirus type 2c Prevalence and genetic characterization of canine parvoviruses in Korea Occurrence of canine parvovirus type 2c in the United States First detection of canine parvovirus type 2c in South America A novel antigenic variant of canine parvovirus from a Vietnamese dog Clinical and virological findings in pups naturally infected by canine parvovirus type 2 Glu-426 mutant Recombinant canine coronaviruses related to transmissible gastroenteritis virus of swine are circulating in dogs Recovery and characterization of a coronavirus from military dogs with diarrhea Genetic diversity of a canine coronavirus detected in pups with diarrhea in Italy Gain, preservation and loss of a group 1a coronavirus accessory glycoprotein The polymerase in its labyrinth: mechanisms and implications of RNA recombination Evolution of positive-strand RNA viruses High frequency RNA recombination of murine coronavirus Experimental infection of dogs with a novel strain of canine coronavirus causing systemic disease and lymphopenia Genotype-specific fluorogenic RT-PCR assays for the detection and quantitation of canine coronavirus type I and type II RNA in faecal samples of dogs Canine distemper and related diseases: report of a severe outbreak in a kennel Infectious canine hepatitis: an ''old'' disease reemerging in Italy Fatal coronavirus infection in puppies following canine parvovirus 2b infection Buonavoglia C (2008) Detection and molecular characterization of a canine norovirus The experimental production of diarrhoea in colostrum deprived axenic and gnotoxenic calves with enteropathogenic Escherichia coli, rotavirus, coronavirus and in a combined infection of rotavirus and E. coli Dual infection of gnotobiotic calves with bovine strains of group A and porcinelike group C rotaviruses influences pathogenesis of the group C rotavirus Evolution of canine parvoviruses -a need for new vaccines? Occurrence of severe gastroenteritis in pups after canine parvovirus vaccine administration: A clinical and laboratory diagnostic dilemma Immunogenicity of an intranasally administered modified live canine parvovirus type 2b vaccine in pups with maternally derived antibodies Cloning and expression of two fragments of the S gene of canine coronavirus type I Phylogenetic analysis of a highly conserved region of the polymerase gene from 11 coronaviruses and development of a consensus polymerase chain reaction assay Sequence analysis of divergent canine coronavirus strains present in a UK dog population Bioedit: a user friendly biological sequence alignment and analysis program for Windows 95/98/NT MEGA4:


id: cord-004790-69lry0ys
author: Smith, A. L.
date: 1986
extension: .txt
mime: text/plain
words: 4419
sentence: 192
flesch: 52
cache: cache/cord-004790-69lry0ys.txt
txt: txt/cord-004790-69lry0ys.txt
title:
  Comparative biological characterization of mouse adenovirus strains FL and K 87 and seroprevalence in laboratory rodents

summary:
  The K 87 strain of mouse adenovirus was kindly supplied by Dr. K. Hashimoto (Tokai University School of Medicine, Isehara, Japan) and was passaged twice in primary suckling mouse kidney cells and tbur times in CMT-93 cells. key: cord-004790-69lry0ys authors: Smith, A. L.; Winograd, Deborah F.; Burrage, T. G. title: Comparative biological characterization of mouse adenovirus strains FL and K 87 and seroprevalence in laboratory rodents date: 1986 journal: Arch Virol DOI: 10.1007/bf01314283 sha: doc_id: 4790 cord_uid: 69lry0ys The growth, stability and seroprevalence in laboratory rodents of the two known strains of mouse adenovirus were compared.


id: cord-004720-r6b34tjm
author: Kaiser, C. J.
title: Inhibition by monensin of human cytomegalovirus DNA replication
date: 1987
extension: .txt
mime: text/plain
words: 4363
sentence: 158
flesch: 40
cache: cache/cord-004720-r6b34tjm.txt
txt: txt/cord-004720-r6b34tjm.txt
summary:
  Previous observations on prevention of HCMV DNA synthesis by glycosylation inhibitors (28, 39) , as well as the findings described here suggest that glyeosylated products participate in the control of viral DNA synthesis. Phosphonoacetic acid (PAA) and monensin were purchased from Sigma, Deisenhofen, Federal Republic of Germany, tunieamycin from Calbiochem, La Jolla, U.S.A. In a typicM experiment for the determination of infected cell DNA synthesis in the presence of monensin, parallel cultures of HFF (5 × 106 cells) were infected by HCMV (MOI of 1) and pulse labelled with att-thymidine (5 ~Ci/ml) during the late phase of the consecutive infectious cycle (28) .


id: cord-271831-vekok62k
author: Dewerchin, H. L.
title: Replication of feline coronaviruses in peripheral blood monocytes
date: 2005-08-01
extension: .txt
mime: text/plain
words: 4709
sentence: 212
flesch: 50
cache: cache/cord-271831-vekok62k.txt
txt: txt/cord-271831-vekok62k.txt
summary:
  The percentage of FIPV infected cells with cytoplasmic expression increased till 24 hpi. Monocytes from the other 2 cats could initially be infected by both FIPV and FECV but FIPV infection was sustained in monocytes of only one cat. FECV-infection was never sustained and viral production was up to 100 times lower than in FIPV-infected monocytes.


id: cord-004755-rmnjs1t6
author: Welch, Siao-Kun Wan
date: 1988
extension: .txt
mime: text/plain
words: 4988
sentence: 228
flesch: 52
cache: cache/cord-004755-rmnjs1t6.txt
txt: txt/cord-004755-rmnjs1t6.txt
title:
  Monoclonal antibodies to a virulent strain of transmissible gastroenteritis virus: comparison of reactivity with virulent and attenuated virus

summary:
  [22] reported that their E 1-specific TGEV MAbs had VN activity only in the presence of 2 to 8 hemolytic units/ml of swine complement. Biochemical and biophysical differences among field isolates and cell cultureattenuated TGEV have been reported [4, 7] , but serologic differences were not identified [13, 14] .


id: cord-004672-0lf5j8lo
author: Anderson, Kevin
date: 1987
extension: .txt
mime: text/plain
words: 5717
sentence: 223
flesch: 53
cache: cache/cord-004672-0lf5j8lo.txt
txt: txt/cord-004672-0lf5j8lo.txt
title:
  Structural and physiological properties of mengovirus: Avirulent, hemagglutination-defective mutants express altered alpha (1 D) proteins and are adsorption-defective

summary:
  These data suggest that arrangement of structural proteins on the surface of mutant eapsids did not differ from that of wild-type. Differenees were deteeted among the alpha (1 D) structural proteins of the wild-type and mutant viruses.


id: cord-026518-xv03vpji
author: Xie, Peng
date: 2020-06-09
extension: .txt
mime: text/plain
words: 5793
sentence: 228
flesch: 48
cache: cache/cord-026518-xv03vpji.txt
txt: txt/cord-026518-xv03vpji.txt
title:
  Immune effect of a Newcastle disease virus DNA vaccine with IL-12 as a molecular adjuvant delivered by electroporation

summary:
  Tracing the origins of genotype VIIh Newcastle disease in southern Africa Intranasal interleukin-12 is a powerful adjuvant for protective mucosal immunity Immunologic responses to West Nile virus in vaccinated and clinically affected horses Electroporation enables plasmid vaccines to elicit CD8 + T cell responses in the absence of CD4 + T cells Updated unified phylogenetic classification system and revised nomenclature for Newcastle disease virus DNA vaccines: progress and challenges Construction of a novel DNA vaccine candidate targeting F gene of genotype VII Newcastle disease virus and chicken IL-18 delivered by Salmonella Electroporation of alphavirus RNA translational reporters into fibroblastic and myeloid cells as a tool to study the innate immune system Cytotoxicity and immunological responses following oral vaccination of nanoencapsulated avian influenza virus H5 DNA vaccine with green synthesis silver nanoparticles Improved immune responses against avian influenza virus following oral vaccination of chickens with HA DNA vaccine using attenuated Salmonella typhimurium as carrier Recent advances in delivery of veterinary DNA vaccines against avian pathogens A novel genotype VII Newcastle disease virus vaccine candidate generated by mutation in the L and F genes confers improved protection in chickens Host innate immune responses of ducks infected with Newcastle disease viruses of different pathogenicities Evaluation of a fusion gene-based DNA prime-protein boost vaccination strategy against Newcastle disease virus Clinical potential of electroporation for gene therapy and DNA vaccine delivery A review of DNA vaccines against influenza The future of human DNA vaccines DNA priming increases frequency of T-cell responses to a vesicular stomatitis virus HIV vaccine with specific enhancement of CD8(+) T-cell responses by interleukin-12 plasmid DNA Isolation, identification, and hexon gene characterization of fowl adenoviruses from a contaminated live Newcastle disease virus vaccine Molecular characterization of new emerging subgenotype VIIh Newcastle disease viruses in China Effects of the HN antigenic difference between the vaccine strain and the challenge strain of Newcastle disease virus on virus shedding and transmission Increased protection against pneumococcal disease by mucosal administration of conjugate vaccine plus interleukin-12 Interleukin-12 as an adjuvant for induction of protective antibody responses Effects of Newcastle disease virus vaccine antibodies on the shedding and transmission of challenge viruses Littel-van den Hurk S (2013) A review on electroporation-based intracellular delivery Immunoadjuvant activities of a recombinant chicken IL-12 in chickens vaccinated with Newcastle disease virus recombinant HN protein Newcastle disease virus-attenuated vaccine LaSota played a key role in the pathogenicity of contaminated exogenous virus Generation and evaluation of a genetically attenuated Newcastle disease virus rGM-VIIm as a genotype-matched vaccine Advancements in DNA vaccine vectors, non-mechanical delivery methods, and molecular adjuvants to increase immunogenicity Sulfated glucan can improve the immune efficacy of Newcastle disease vaccine in chicken Interleukin-12 gene adjuvant increases the immunogenicity of virus-like particles of human papillomavirus type 16 regional variant strain Direct gene transfer into mouse muscle in vivo Preparation and efficacy of Newcastle disease virus DNA vaccine encapsulated in chitosan nanoparticles IgA response and protection following nasal vaccination of chickens with Newcastle disease virus DNA vaccine nanoencapsulated with Ag@SiO2 hollow nanoparticles Immune effect of Newcastle disease virus DNA vaccine with c3d as a molecular adjuvant


id: cord-001274-vz0qvp01
author: Chitray, M.
date: 2013-11-13
extension: .txt
mime: text/plain
words: 6324
sentence: 216
flesch: 45
cache: cache/cord-001274-vz0qvp01.txt
txt: txt/cord-001274-vz0qvp01.txt
title:
  Genetic heterogeneity in the leader and P1-coding regions of foot-and-mouth disease virus serotypes A and O in Africa

summary:
  These could be grouped into three major restricted genotypes, i.e., Euro-South America, Asia and Africa, based on 1D phylogeny (this study only included FMDV A viruses from Euro-South America and Africa) Similarly, based on 1D phylogeny, type O viruses were divided into three groups: those originating from Asia, Europe-South America and the Far East


id: cord-004743-ido065mh
author: Nagy, Éva
title: Polypeptide patterns of infectious bronchitis virus serotypes fall into two categories
date: 1979
extension: .txt
mime: text/plain
words: 1071
sentence: 35
flesch: 44
cache: cache/cord-004743-ido065mh.txt
txt: txt/cord-004743-ido065mh.txt
summary:
  key: cord-004743-ido065mh authors: Nagy, Éva; Lomniczi, B. title: Polypeptide patterns of infectious bronchitis virus serotypes fall into two categories date: 1979 journal: Arch Virol DOI: 10.1007/bf01315022 sha: doc_id: 4743 cord_uid: ido065mh Molecular weights of six major polypeptides of infectious bronchitis virus (IBV) are: 1. 75,000; 2. 50,000; 3. 45,000; 4. 35,000; 5. 28,000 or 24,000, and 6. 22,000 dalton. The polypeptide composition of avian infectious bronchitis virus Heterogeneity of infectious bronchitis virus grown in eggs Antigenic variation in strains of avian infectious bronchitis virus Serological comparison of strains of infectious bronchitis virus using plaque-purified isolants Cleavage of structural proteins during the assembly of bacteriophage T4 Characterization of infectious bronchitis virus Serologic differences between strains of infectious bronchitis virus from New ZeMand, Australia, and the United States Isolation of the virus of infectious bronchitis Genome of infectious bronchitis virus The polypeptide composition of avian infectious bronchitis virus particles Coronaviruses: a comparative review Characterization of the strueturM proteins of different strains of Newcastle disease virus Reproduction of togaviruses Presence of infectious polyadenylated I%NA in the eoronavirus avian bronchitis virus The evaluation of AKR leukemia virus purity: The requirement for both velocity and isopycnie eentrifugation methods The skillful technical assistance of Mrs. Sz. Sz6esy is appreciated.


id: cord-048485-b8xb1f12
author: Hulst, Marcel
date: 2008-06-04
extension: .txt
mime: text/plain
words: 6320
sentence: 256
flesch: 41
cache: cache/cord-048485-b8xb1f12.txt
txt: txt/cord-048485-b8xb1f12.txt
title:
  Early transcriptional response in the jejunum of germ-free piglets after oral infection with virulent rotavirus

summary:
  The rotavirus enterotoxin NSP4 mobilizes intracellular calcium in human intestinal cells by stimulating phospholipase C-mediated inositol 1, 4, 5-trisphosphate production Rotaviruses and their replication Transmission of F4 + E coli in groups of early weaned piglets Molecular cloning of spermidine/spermine N1-acetyltransferase from the periimplantation porcine uterus by messenger ribonucleic acid differential display: temporal and conceptus-modulated gene expression Twists and turns in the development and maintenance of the mammalian small intestine epithelium Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation Inactivation of the RNase activity of glycoprotein E rns of classical swine fever virus results in a cytopathogenic virus Increased thioredoxin-1 inhibits SSAT expression in MCF-7 human breast cancer cells Inclusion of linseed and linseed expeller meal in piglet diets affects intestinal gene expression profiles Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation Rotavirus infection reduces sucrase-isomaltase expression in human intestinal epithelial cells by perturbing protein targeting and organization of microvillar cytoskeleton Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes Role of the enteric nervous system in the fluid and electrolyte secretion of rotavirus diarrhea Pathogenesis of rotavirus diarrhea Mechanisms of CD47-induced caspase-independent cell death in normal and leukemic cells: link between phosphatidylserine exposure and cytoskeleton organization Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation State University of Utrecht 33. It is tempting to link up-regulation of MS4A2 directly to NSP4induced enhancement of Ca 2+ permeability of the plasma and ER membranes in intestinal epithelial cells [29, 40] .


id: cord-004774-fvf671jn
author: Kjeldsberg, Elisabeth
title: Detection of astroviruses in gut contents of nude and normal mice
date: 1985
extension: .txt
mime: text/plain
words: 1609
sentence: 72
flesch: 52
cache: cache/cord-004774-fvf671jn.txt
txt: txt/cord-004774-fvf671jn.txt
summary:
  In this note we report the detection of astrovirus-like partieles in gut contents from nude mice, with and without clinical signs of illness, and from normal symptomless mice in association with an outbreak of diarrhea. No attempt was made to quantify the amount of virus in the samples, but there appeared to be a higher number of virus particles in the samples from animals with diarrhea than from those without.


id: cord-265768-hwki5lk2
author: Abi, Keha-mo
date: 2020-10-06
extension: .txt
mime: text/plain
words: 1969
sentence: 64
flesch: 41
cache: cache/cord-265768-hwki5lk2.txt
txt: txt/cord-265768-hwki5lk2.txt
title:
  An emerging novel bovine coronavirus with a 4-amino-acid insertion in the receptor-binding domain of the hemagglutinin-esterase gene

summary:
  It is worth noting that the R3-loop is composed of 13 aa (aa 207 -219) in BCoV HE, and residues F 211, L 212, S 213, and N 214 are essential for receptor-ligand interaction [3] . Interestingly, the inserted sequence in HE in this study may have originated from bovine chromosomal DNA, which may provide an evolutionary advantage for BCoV, and its identification should enhance our current understanding of the genetic evolution of BCoV. The BCoV strain with a recombinant HE (designated as SWUN/A1/2018) and BCoV strain with a recombinant HE containing an insertion (designated as SWUN/A10/2018) successfully isolated in Vero cell culture.


id: cord-004728-rjl35dpa
author: Taguchi, F.
title: Asymptomatic infection of mouse hepatitis virus in the rat
date: 1979
extension: .txt
mime: text/plain
words: 959
sentence: 33
flesch: 43
cache: cache/cord-004728-rjl35dpa.txt
txt: txt/cord-004728-rjl35dpa.txt
summary:
  key: cord-004728-rjl35dpa authors: Taguchi, F.; Yamada, A.; Fujiwara, K. title: Asymptomatic infection of mouse hepatitis virus in the rat date: 1979 journal: Arch Virol DOI: 10.1007/bf01317424 sha: doc_id: 4728 cord_uid: rjl35dpa After intranasal inoculation of suckling rats mouse hepatitis virus multiplied mostly in the nasal epithelium; though there were no symptoms, antibodies were produced. An attempt at serological checking by anamnestic response Mouse hepatitis virus and its pathogenic action Antibodies to mouse hepatitis virus in human sera Pathogenicity of mouse hepatitis virus for mice depending upon host age and route of infection Isolation of low-virulent mouse hepatitis virus from nude mice with wasting syndrome and hepatitis Pathogenesis of sialodaeryoadenitis in gnotobiotic rats Rat eoronavirus (1%CV): a prevalent, naturally occurring pneumotie virus of rats Experimental viral hepatitis Mouse hepatitis virus infection as a. highly contagious, prevMent, enteric infection of mice Difference in response to mouse hepatitis virus a, mong suseeptible mouse strMns Age-dependent response of mice to a mouse hepatitis virus, MttV-S. Japan We th~nk Dr. T. Sato (Chugai pharmaceutical Co., LTD) and Dr. H. ikeda of the same Institute for their many helpful discussions of the research.


id: cord-011105-or9azf1g
author: Huang, Zheng
date: 2020-04-30
extension: .txt
mime: text/plain
words: 2440
sentence: 124
flesch: 53
cache: cache/cord-011105-or9azf1g.txt
txt: txt/cord-011105-or9azf1g.txt
title:
  Full-genome sequences of GII.13[P21] recombinant norovirus strains from an outbreak in Changsha, China

summary:
  Norovirus outbreaks in public spaces, such as kindergartens and primary or secondary schools, are generally associated with low hygiene levels and contaminated food or water Evolution of norovirus Genotypic and epidemiologic trends of norovirus outbreaks in the United States Environmental Surveillance for Noroviruses in Selected South African Wastewaters Outbreaks of norovirus and acute gastroenteritis associated with British Columbia Oysters Structure(s), function(s), and inhibition of the RNA-dependent RNA polymerase of noroviruses Advances in laboratory methods for detection and typing of norovirus Updated classification of norovirus genogroups and genotypes Proposal for a unified norovirus nomenclature and genotyping Mechanisms of GII.4 norovirus evolution Emergence and predominance of norovirus GII Emergence of a new GII.17 norovirus variant in patients with acute gastroenteritis in Gastroenteritis Outbreaks Caused by Norovirus GII An outbreak of gastroenteritis associated with GII.17 Norovirus-contaminated secondary water supply system in Wuhan Noroviruses Recognize Glycans with a Terminal beta-Galactose via an Unconventional Glycan Binding Site A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface Human norovirus transmission and evolution in a changing world Epidemiology of Norovirus outbreaks reported to the public health emergency event surveillance system, China A norovirus intervariant GII.4 recombinant in Victoria Emergence of norovirus GII.P16-GII.2 strains in patients with acute gastroenteritis in Huzhou Emergence of Norovirus GII.17 variants among children with acute gastroenteritis in South Korea Analysis of uncommon norovirus recombinants from Manaus, Amazon region, Brazil: GII.P22/GII.5, GII.P7/GII.6 and GII Novel recombinant GII.P16_GII.13 and GII.P16_GII.3 norovirus strains in Italy Full-genomic analysis of a human norovirus recombinant GII.12/13 novel strain isolated from South Korea Full-genome sequence analysis of an uncommon norovirus genotype, GII.21, from South Korea Detection of norovirus and rotavirus present in suspended and dissolved forms in drinking water sources Emergence of GII.4 Sydney norovirus in South Korea during the winter of 2012-2013 Distribution of norovirus and sapovirus genotypes with emergence of NoV GII.P16/GII.2 recombinant strains in Chiang Mai, Thailand GII.21 in children with Diarrhea Occurrence of novel GII.17 and GII.21 norovirus variants in the coastal environment of South Korea in 2015 Norovirus-host interaction: implications for disease control and prevention Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Acknowledgements


id: cord-004827-bnf3mvaf
author: Desselberger, U.
title: Report on an ICTV-sponsored symposium on Virus Evolution
date: 2005-01-13
extension: .txt
mime: text/plain
words: 2768
sentence: 126
flesch: 43
cache: cache/cord-004827-bnf3mvaf.txt
txt: txt/cord-004827-bnf3mvaf.txt
summary:
  The viruses and their replication Molecular evidence of HIV-1 transmission in a criminal case The nonclonal and transitory nature of HIV in vivo Don't forget about viruses Topological organization of picornaviral genomes: Statistical prediction of RNA structural signals New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma Reproducible nonlinear population dynamics and critical points during replicative competitions of RNA virus quasispecies Retroids in Archaea: phylogeny and lateral origins The structure of a thermophilic archaeal virus shows a double stranded DNA viral capsid that spans all domains of life Generation of coronavirus spike deletion variants by high-frequency recombination at regions of predicted RNA secondary structure Evolutionary history of Cucumber mosaic virus deduced by phylogenetic analyses Plant RNA virus evolution Synchronous loss of quasispecies memory in parallel viral lineages: a deterministic feature of viral quasispecies Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) New Haven CT 30. A new model for coronavirus transcription Genetic diversity in RNA virus quasispecies is controlled by host-virus interaction Unique and conserved features of genome and proteome of SARS-coronavirus, an early split off from the coronavirus group 2 lineage Of statistics and genomes VP1 of infectious bursal disease virus is an RNA dependent RNA polymerase The 3C-like proteinase of an invertebrate nidovirus links coronavirus and potyvirus homologs On finding all suboptimal foldings of an RNA molecule Prediction of RNA secondary structure by energy minimization Parc d'Innovation, Boulevard Sébastian Brandt, 67400 Illkirch, France.


id: cord-004802-rhkrmftn
author: Hoshino, Y.
title: Isolation and characterization of a canine rotavirus
date: 1982
extension: .txt
mime: text/plain
words: 2909
sentence: 107
flesch: 37
cache: cache/cord-004802-rhkrmftn.txt
txt: txt/cord-004802-rhkrmftn.txt
summary:
  No antigenic relationship was found between this canine rotavirus and two human rotaviruses by plaque reduction neutralization assay (Table 2) , although we have observed that there is a one-way antigenic relationship between this isolate of canine rotavirus and another strain of human rotavirus (Hosm•o, Y. et al., unpublished results). Canine rotavirus (CUd) induced intracytoplasmic inclusion bodies in MAt04 cells.


id: cord-004778-xrv0qs6n
author: Smith, C. B.
date: 1986
extension: .txt
mime: text/plain
words: 3379
sentence: 123
flesch: 44
cache: cache/cord-004778-xrv0qs6n.txt
txt: txt/cord-004778-xrv0qs6n.txt
title:
  Mouse cytomegalovirus is infectious for rats and alters lymphocyte subsets and spleen cell proliferation

summary:
  Seven days after MCMV infection, there was a generalized increase in(3)H-thymidine incorporation by spleen cells in both resting (unstimulated) cultures and cultures exposed to mitogens (Con A, PHA, LPS) and to MCMV antigen. Seven days after MCMV infection, a consistently greater proliferation of spleen cells from MCMV infected rats as compared to control animMs was seen with M1 mitogens and also in unstimulated background cultures (Table 2 and Fig. 1 and 2 ).


id: cord-258374-qht98q0l
author: Takano, Tomomi
date: 2009-04-03
extension: .txt
mime: text/plain
words: 3701
sentence: 148
flesch: 39
cache: cache/cord-258374-qht98q0l.txt
txt: txt/cord-258374-qht98q0l.txt
title:
  Neutrophil survival factors (TNF-alpha, GM-CSF, and G-CSF) produced by macrophages in cats infected with feline infectious peritonitis virus contribute to the pathogenesis of granulomatous lesions

summary:
  Risk of feline infectious peritonitis in cats naturally infected with feline coronavirus Gamma interferon/interleukin 10 balance in tissue lymphocytes correlates with down modulation of mucosal feline immunodeficiency virus infection Immune and idiopathic neutropenia Replication of feline coronaviruses in peripheral blood monocytes Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation Polymorphonuclear leukocytemediated cell and tissue injury: oxygen metabolites and their relations to human disease Neutrophil elastase up-regulates cathepsin B and matrix metalloprotease-2 expression The molecular genetics of feline coronaviruses: comparative sequence analysis of the ORF7a/7b transcription unit of different biotypes A study on the mechanism of antibody-dependent enhancement of feline infectious peritonitis virus infection in feline macrophages by monoclonal antibodies Enhancement and neutralization of feline infectious peritonitis virus infection in feline macrophages by neutralizing monoclonal antibodies recognizing different epitopes The role of IgG subclass of mouse monoclonal antibodies in antibody-dependent enhancement of feline infectious peritonitis virus infection of feline macrophages Morphologic features and development of granulomatous vasculitis in feline infectious peritonitis Spontaneous neutrophil apoptosis and regulation of cell survival by granulocyte macrophage-colony stimulating factor Asymptomatic bacteriuria in puppies with canine parvovirus infection: a cohort study Neutropenia, neutrophil dysfunction, and bacterial infection in patients with human immunodeficiency virus disease: the role of granulocyte colony-stimulating factor Epstein-Barr virus infects and induces apoptosis in human neutrophils Marrow accessory cell infection and alterations in hematopoiesis accompany severe neutropenia during experimental acute infection with feline immunodeficiency virus Virus infection of endothelial cells increases granulocyte adherence Molecular cloning and sequence determination of the peplomer protein gene of feline infectious peritonitis virus type I Comparison of the amino acid sequence and phylogenetic analysis of the peplomer, integral membrane and nucleocapsid proteins of feline, canine and porcine coronaviruses In vitro effect of recombinant human granulocyte colonystimulating factor on canine neutrophil apoptosis In vitro effect of recombinant human tumor necrosis factor-alpha on canine neutrophil apoptosis A review of feline infectious peritonitis virus: molecular biology, immunopathogenesis, clinical aspects, and vaccination The acute phase reaction Some aspects of humoral and cellular immunity in naturally occurring feline infectious peritonitis Pathogenesis of feline panleukopenia virus and canine parvovirus Programmed cell death of the normal human neutrophil: an in vitro model of senescence Feline infectious peritonitis and feline enteric coronavirus infections. In addition, the presence or absence of neutrophil survival factors was investigated in specimens collected from cats with FIP.


id: cord-029775-mntcor5d
author: Oka, Tomoichiro
title: Polymerase chain reaction primer sets for the detection of genetically diverse human sapoviruses
date: 2020-07-27
extension: .txt
mime: text/plain
words: 1844
sentence: 64
flesch: 47
cache: cache/cord-029775-mntcor5d.txt
txt: txt/cord-029775-mntcor5d.txt
summary:
  62nt-CTGCTATCCTGCCACCAGGTG CACAGGGGCAGTCACGAGTAA-75nt-TTTCCTTGGGGCTATCCACC-35nt-AGCGCA ATGTTTGCTGGGTGGGG -62nt-CTGCCATCTTGCCACCCGGAG TACAGGGGCCGTCAGCAACAA-75nt-CTTTCTTGGTGCCATCCATC-35nt-AGTGCC ATGTTTGCTGGCTGGGG -62nt-TCGCAGTGCTGCCTCCAGGTG AACTGGGGCAGTCACCAGCAA-75nt-GTTCCTGGGCGCAATCCACC Comprehensive review of human sapoviruses Children attending day care centers are a year-round reservoir of gastrointestinal viruses A foodborne outbreak of sapovirus linked to catered box lunches in Japan Characterization of sapoviruses detected in gastroenteritis outbreaks and identification of asymptomatic adults with high viral load Detection of human sapovirus by real-time reverse transcription-polymerase chain reaction Human sapovirus classification based on complete capsid nucleotide sequences Genetic diversity of human sapovirus across the Americas Viral metagenomics reveals sapoviruses of different genogroups in stool samples from children with acute gastroenteritis in Jiangsu Investigation of a food-borne outbreak of gastroenteritis in a school canteen revealed a variant of sapovirus genogroup V not detected by standard PCR Complete genome sequence of a novel GV.2 sapovirus strain, NGY-1, detected from a suspected foodborne gastroenteritis outbreak Broadly reactive real-time reverse transcription-polymerase chain reaction assay for the detection of human sapovirus genotypes Molecular epidemiology and phylogenetic analysis of Sapporo-like viruses The detection of human sapoviruses with universal and genogroup-specific primers Detection of norovirus (GI, GII), Sapovirus and astrovirus in fecal samples using reverse transcription single-round multiplex PCR Detection and genetic analysis of human sapoviruses in river water in Japan Surveillance of pathogens in outpatients with gastroenteritis and characterization of sapovirus strains between Epidemiology and genotype analysis of sapovirus associated with gastroenteritis outbreaks in A confirmation of sapovirus re-infection gastroenteritis cases with different genogroups and genetic shifts in the evolving sapovirus genotypes Quantification and genotyping of human sapoviruses in the Llobregat river catchment Near-Complete Human Sapovirus Genome Sequences from Kenya PCR assays were performed using 20 µL of a reaction mixture containing 1 µL of synthetic double-stranded DNA or 2 µL of cDNA or DNA from clinical specimens, 10 µL of KAPA2G Fast HotStart ReadyMix with dye (KAPA Biosystems, Wilmington, MA), and 10 pmol of each primer.


id: cord-004812-ikco4h5k
author: Moore, K. M.
date: 1997-04-06
extension: .txt
mime: text/plain
words: 2736
sentence: 125
flesch: 51
cache: cache/cord-004812-ikco4h5k.txt
txt: txt/cord-004812-ikco4h5k.txt
title:
  Identification of amino acids involved in a serotype and neutralization specific epitope with in the s1 subunit of avian infectious bronchitis virus

summary:
  Reverse transcriptase-polymerase chain reaction (RT-PCR) with primers MIBVPCR and NIBVPCR amplify a conserved region in IBV con®rming Mab NR mutants as IBV Numbers represent the AA substitutions observed in Mab NR mutants in which 304 and 386 were the most frequently observed substitutions.


id: cord-255653-0bj5eh5d
author: Pensaert, M. B.
date: 1981
extension: .txt
mime: text/plain
words: 2522
sentence: 127
flesch: 47
cache: cache/cord-255653-0bj5eh5d.txt
txt: txt/cord-255653-0bj5eh5d.txt
title:
  An immunoelectron microscopic and immunofluorescent study on the antigenic relationship between the coronavirus-like agent, CV 777, and several coronaviruses

summary:
  CVLA did not show cross reactivity with infectious bronchitis virus, transmissible gastroenteritis virus (TGEV), canine coronavirus (CCV) hemagglutinating encephalomyelitis virus (HEV), neonatal calf diarrhea coronavirus (NCDCV) or feline infectious peritonitis virus (FIPV). The CVLA was shown by serologic cross protection studies to differ from the two knowm porcine coronaviruses, transmissible gastroenteritis virus (TGEV) and hemagglntinating encephalomyelitis virus (HEV) (4, 14) .


id: cord-004848-2cfphi88
author: Carter, M. J.
title: Transcription of feline calicivirus RNA
date: 1990
extension: .txt
mime: text/plain
words: 3361
sentence: 154
flesch: 56
cache: cache/cord-004848-2cfphi88.txt
txt: txt/cord-004848-2cfphi88.txt
summary:
  [10] employing oligo-dT as primer for the reverse transcription of 2 gg of virus RNA. We have used this to probe FCV-infected cells for the synthesis of virus specific RNA and confirm and extend the observations of Neill and Mengeling.


id: cord-252232-vgq6gjpx
author: Hou, Yuxuan
date: 2010-06-22
extension: .txt
mime: text/plain
words: 3224
sentence: 107
flesch: 48
cache: cache/cord-252232-vgq6gjpx.txt
txt: txt/cord-252232-vgq6gjpx.txt
title:
  Angiotensin-converting enzyme 2 (ACE2) proteins of different bat species confer variable susceptibility to SARS-CoV entry

summary:
  Another important finding of our current study is the great genetic diversity of bat ACE2 proteins, which is in contrast to the genetically homogenous hACE2 [10] . Chimeric ACE2 was constructed by combining the N-terminal region of bat ACE2 with the C-terminal portion of human ACE2 at the unique BamHI site (1,070-1,075 bp).


id: cord-004769-hhge62sl
author: Remond, M.
date: 1992
extension: .txt
mime: text/plain
words: 3273
sentence: 142
flesch: 54
cache: cache/cord-004769-hhge62sl.txt
txt: txt/cord-004769-hhge62sl.txt
title:
  Partial DNA cloning and sequencing of a canine parvovirus vaccine strain: application of nucleic acid hybridization to the diagnosis of canine parvovirus disease

summary:
  Eight recombinant clones containing CPV sequences were selected by colony hybridization, Six clones contained an insert of the 2 kb; as expected the other two contained 1.5 kb and 1.3 kb inserts. To elucidate whether the deletion observed was originally in the vaccine or was generated by cell culture passages in our laboratory, DNA sequence was determined on CPV-b 108 after PCR amplification of a 1000 bp fragment including the deleted region and the two H i n


id: cord-004673-c8qcjve9
author: Faaberg, K. S.
date: 1996
extension: .txt
mime: text/plain
words: 4659
sentence: 170
flesch: 49
cache: cache/cord-004673-c8qcjve9.txt
txt: txt/cord-004673-c8qcjve9.txt
title:
  Membrane association of the C-terminal half of the open reading frame 1a protein of lactate dehydrogenase-elevating virus

summary:
  The primary findings concerning the A69 and 183-1 proteins were that they are, as predicted by their hydrophobicity profiles, integral membrane proteins and that they are not N-glycosylated. encoding ORF 1a protein segments encompassing transmembrane segments 5 to 11 and its amphipathic C-terminal end as well as the N-terminal 80 amino acids of the downstream ORF 1b protein were transcribed and the transcripts in vitro translated in the absence and presence of microsomal membranes.


id: cord-004825-cdvnqfjz
author: Castilla, V.
title: The entry of Junin virus into Vero cells
date: 1994
extension: .txt
mime: text/plain
words: 2671
sentence: 112
flesch: 45
cache: cache/cord-004825-cdvnqfjz.txt
txt: txt/cord-004825-cdvnqfjz.txt
summary:
  [16-1 have shown that Sindbis virus infected cells express a fusion function after treatment at acid pH. We demonstrated that Junin virus can mediate cell fusion at pH 5.5 producing polykaryocytes in which over 40% of the cells in the monolayer participate (Fig. 6) . To investigate whether ammonium chloride affects JV internalization, virus adsorbed cells at 4 °C were warmed to 37 ~C for various intervals in presence or absence of the compound and internalized virus was determined by infectious center assay.


id: cord-004717-41ui4lqc
author: Laurin, Marc-André
date: 2011-09-08
extension: .txt
mime: text/plain
words: 2226
sentence: 94
flesch: 44
cache: cache/cord-004717-41ui4lqc.txt
txt: txt/cord-004717-41ui4lqc.txt
title:
  Detection and genetic characterization of a novel pig astrovirus: relationship to other astroviruses

summary:
  The data reported in this study extend the number of porcine astrovirus lineages to a total of five, all of which most likely represent distinct species of different origins. The general strategy employed for obtaining PoAstV sequences is summarized in Fig. 1 .


id: cord-004838-cdas57cx
author: Morozov, I.
date: 1995
extension: .txt
mime: text/plain
words: 2241
sentence: 97
flesch: 55
cache: cache/cord-004838-cdas57cx.txt
txt: txt/cord-004838-cdas57cx.txt
title:
  Sequence analysis of open reading frames (ORFs) 2 to 4 of a U.S. isolate of porcine reproductive and respiratory syndrome virus

summary:
  The cDNA clones containing PRRSV specific sequences were selected using a VR2385 ORF 4 specific PCR probe and sequenced. The cDNA clones containing PRRSV specific sequences were selected using a VR2385 ORF 4 specific PCR probe and sequenced.


id: cord-263193-paeosfiu
author: Zhu, Jinyan
title: Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway
date: 2020-06-10
extension: .txt
mime: text/plain
words: 2847
sentence: 121
flesch: 49
cache: cache/cord-263193-paeosfiu.txt
txt: txt/cord-263193-paeosfiu.txt
summary:
  Importantly, we found significant activation of the TLR3-TRIF pathway and inhibition of the TLR7-MYD88 pathway at 48 hpi by different IBV strains in CEK cells. The effect of agonists and inhibitors on the replication of different IBV strains.


id: cord-272973-kzaowysv
author: Joshi, Lok R.
date: 2018-05-03
extension: .txt
mime: text/plain
words: 4285
sentence: 176
flesch: 50
cache: cache/cord-272973-kzaowysv.txt
txt: txt/cord-272973-kzaowysv.txt
title:
  Passive immunity to porcine epidemic diarrhea virus following immunization of pregnant gilts with a recombinant orf virus vector expressing the spike protein

summary:
  (E) Correlation of group mean IgG antibodies in piglet serum with piglet serum NA levels. (F) Correlation of group mean IgA antibodies in piglet serum with piglet serum NA levels.


id: cord-012032-zolowuhj
author: Yu, Peifa
date: 2020-08-08
extension: .txt
mime: text/plain
words: 3511
sentence: 146
flesch: 39
cache: cache/cord-012032-zolowuhj.txt
txt: txt/cord-012032-zolowuhj.txt
title:
  2’-Fluoro-2’-deoxycytidine inhibits murine norovirus replication and synergizes MPA, ribavirin and T705

summary:
  The combination of 2’-FdC with mycophenolic acid, ribavirin or favipiravir (T705) exerts synergistic antiviral effects. Human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and murine The 50% cytotoxic concentration (CC 50 ) (n = 16) and 50% inhibitory concentration (IC 50 ) (n = 4-6) against viral replication were calculated using GraphPad Prism 5 software.


id: cord-256859-7ixegm72
author: Liu, S. W.
date: 2006-01-09
extension: .txt
mime: text/plain
words: 5161
sentence: 178
flesch: 47
cache: cache/cord-256859-7ixegm72.txt
txt: txt/cord-256859-7ixegm72.txt
title:
  Genetic diversity of avian infectious bronchitis coronavirus strains isolated in China between 1995 and 2004

summary:
  IBV strains have been isolated and identified since 1982 in China. The diversity of the pathogenicity of IBV strains was expected; although the primary tissue of IBV infection is the respiratory tract, some isolates can grow in nonrespiratory organs such as the kidney, the female reproductive tract, intestine, and spleen of chickens [2, 14, 33, 36] .


id: cord-006674-ywzpwlrb
author: Ikeda, T.
date: 1992
extension: .txt
mime: text/plain
words: 3721
sentence: 162
flesch: 42
cache: cache/cord-006674-ywzpwlrb.txt
txt: txt/cord-006674-ywzpwlrb.txt
title:
  Pathogenesis of cytomegalovirus-associated pneumonitis in ICR mice: possible involvement of superoxide radicals

summary:
  For infection mice were anesthetized with 200 mg/kg body weight of 2,2,2-tribromoethanol (Avertin; Aldrich Chemical Co., Milwaukee, WI, U.S.A.) and 0.05ml of virus stock (7 x t04pFU) was instilled into the nose. key: cord-006674-ywzpwlrb authors: Ikeda, T.; Shimokata, K.; Daikoku, T.; Fukatsu, T.; Tsutsui, Y.; Nishiyama, Y. title: Pathogenesis of cytomegalovirus-associated pneumonitis in ICR mice: possible involvement of superoxide radicals date: 1992 journal: Arch Virol DOI: 10.1007/bf01309571 sha: doc_id: 6674 cord_uid: ywzpwlrb We have studied the pathogenesis of murine cytomegalovirus (MCMV) pneumonitis in immunocompetent ICR mice and in mice treated with cyclophosphamide (CP).


id: cord-004713-gzts5h0y
author: Fennestad, K. L.
title: Pathogenetic observations on pleural effusion disease in rabbits
date: 1985
extension: .txt
mime: text/plain
words: 3603
sentence: 158
flesch: 49
cache: cache/cord-004713-gzts5h0y.txt
txt: txt/cord-004713-gzts5h0y.txt
summary:
  To examine viral growth and persistence of viraemia, serum was assayed for virus content at various times after rabbit infection with the two isolates ( Figs. 2 and 3 ). The findings, corrobated with other closely comparable observations, suggest that the emergence of PED as an intercurrent mortality problem during rabbit passage of pathogenicTreponema pallidum is the result of a specific selective pressure on a benign passenger virus.


id: cord-261749-lq1ah16x
author: Mayo, M. A.
date: 2006-03-03
extension: .txt
mime: text/plain
words: 2290
sentence: 90
flesch: 54
cache: cache/cord-261749-lq1ah16x.txt
txt: txt/cord-261749-lq1ah16x.txt
title:
  Report from the 36(th) and the 37(th) Meetings of the Executive Committee of the International Committee on Taxomony of Viruses

summary:
  • It would make clear the distinction between species names and virus names. The changes proposed further stipulated that ICTV should keep an official list of virus names that were used previously but are no longer in current taxonomy.


id: cord-265631-b0kg6qpo
author: Saeng-chuto, Kepalee
date: 2017-03-23
extension: .txt
mime: text/plain
words: 1604
sentence: 69
flesch: 47
cache: cache/cord-265631-b0kg6qpo.txt
txt: txt/cord-265631-b0kg6qpo.txt
title:
  Retrospective investigation and evolutionary analysis of a novel porcine deltacoronavirus strain detected in Thailand from 2008 to 2015

summary:
  The genetic diversity and complete genome analysis of two novel porcine deltacoronavirus isolates in Thai The first detection and full-length genome sequence of porcine deltacoronavirus isolated in Lao PDR Different lineage of porcine deltacoronavirus in Thailand, Vietnam and Lao PDR in 2015 PCRbased retrospective evaluation of diagnostic samples for Porcine deltacoronavirus in Thailand 2107 emergence of porcine deltacoronavirus in US swine Genetic diversity of ORF3 and spike genes of porcine epidemic diarrhea virus in Thailand CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus Acknowledgements Interestingly, the PDCoV variants in Thailand are different from variants in other countries and belong to a novel group of PDCoV strains.


id: cord-004719-3stcx0dd
author: Mushegian, A. R.
date: 1993
extension: .txt
mime: text/plain
words: 6347
sentence: 217
flesch: 38
cache: cache/cord-004719-3stcx0dd.txt
txt: txt/cord-004719-3stcx0dd.txt
title:
  Cell-to-cell movement of plant viruses: Insights from amino acid sequence comparisons of movement proteins and from analogies with cellular transport systems

summary:
  Also, as binding of movement proteins to RNA is thought not to be sequence-specific [14, 17] , it could be anticipated that the majority of movement protein will bind to cellular RNAs, which in the case of TMV infection are in excess over virus RNAs at the time when 30 kD protein is transiently expressed [18] . All the proteins containing the conserved motifs shown in Fig. 1 should be considered a single vast, and highly diverged superfamily of plant virus movement proteins.


id: cord-004793-6yh36r0w
author: Choi, C. S.
title: Replication of two porcine parvovirus isolates at non-permissive temperatures
date: 1990
extension: .txt
mime: text/plain
words: 3234
sentence: 149
flesch: 53
cache: cache/cord-004793-6yh36r0w.txt
txt: txt/cord-004793-6yh36r0w.txt
summary:
  In order to understand the relationship between permissive temperatures for virus replication and their pathogenicity in vivo, virus isolates were serially passaged in vitro at non-permissive temperatures. This finding was also observed with Kresse virus isolate continuously passaged at 37°C.


id: cord-266716-pghnl980
author: Wang, Hai-Ming
date: 2018-02-06
extension: .txt
mime: text/plain
words: 3412
sentence: 135
flesch: 43
cache: cache/cord-266716-pghnl980.txt
txt: txt/cord-266716-pghnl980.txt
title:
  Isobavachalcone inhibits post-entry stages of the porcine reproductive and respiratory syndrome virus life cycle

summary:
  In this study, we observed that isobavachalcone (IBC), which was first isolated from Psoralea corylifolia, had potent anti-PRRSV activity in vitro. In the current study, for the first time, we observed that IBC has anti-PRRSV activity.


id: cord-004694-43yvs52a
author: Han, Tae-Hee
date: 2009-05-05
extension: .txt
mime: text/plain
words: 1990
sentence: 73
flesch: 49
cache: cache/cord-004694-43yvs52a.txt
txt: txt/cord-004694-43yvs52a.txt
title:
  Detection of human rhinovirus C in children with acute lower respiratory tract infections in South Korea

summary:
  To our knowledge, this is the first study to confirm the presence of HRV C infection in children with acute LRTIs in Korea. Although several novel HRV species have been identified due to the development of molecular methodology, it is difficult to compare these novel HRVs because different regions of the genome have been used for analysis.


id: cord-004754-5596p4ma
author: Duan, X.
date: 2014-04-06
extension: .txt
mime: text/plain
words: 4888
sentence: 199
flesch: 45
cache: cache/cord-004754-5596p4ma.txt
txt: txt/cord-004754-5596p4ma.txt
title:
  Effects of origin and state of differentiation and activation of monocytes/macrophages on their susceptibility to porcine reproductive and respiratory syndrome virus (PRRSV)

summary:
  For determining the titre of extracellular virus, medium from PRRSV infected cells was collected and centrifuged at 9000 Â g for 15 min. 100 ml of tenfold dilutions of the supernatants were inoculated in 96-well microtiter plates (Nalge Nunc, Roskilde, Denmark) previously seeded with AMf. Table 1 shows the virus titres and percentage of PRRSV positive cells in freshly isolated and one day cultivated AMf at 1, 24 and 48 h after PRRSV inoculation.


id: cord-004851-h9ppa064
author: Plagemann, P. G. W.
title: Hepatitis C virus
date: 1991
extension: .txt
mime: text/plain
words: 6839
sentence: 283
flesch: 45
cache: cache/cord-004851-h9ppa064.txt
txt: txt/cord-004851-h9ppa064.txt
summary:
  It also has become apparent that HepCV RNA becomes detectable by polymerase chain reaction (PCR) procedures much sooner after infection than anti-HepCV antibodies and that HepCV RNA might be detectable in the absence of detectable levels of serum antibodies. HepCV RNA was detectable in serum of two experimentMly infected chimpanzees 3 days p.i.


id: cord-004764-tmvebf23
author: Stephenson, J. R.
title: A comparative analysis of measles virus RNA by oligonucleotide fingerprinting
date: 1982
extension: .txt
mime: text/plain
words: 4855
sentence: 239
flesch: 63
cache: cache/cord-004764-tmvebf23.txt
txt: txt/cord-004764-tmvebf23.txt
summary:
  Similar observations have been noted when the genomes of several R N A viruses were analysed b y this method (2I). t e r n shown in Fig.


id: cord-267155-3rhdxzj3
author: Sato, K.
title: Serological relation between calf diarrhea coronavirus and hemagglutinating encephalomyelitis virus
date: 1980
extension: .txt
mime: text/plain
words: 1271
sentence: 60
flesch: 59
cache: cache/cord-267155-3rhdxzj3.txt
txt: txt/cord-267155-3rhdxzj3.txt
summary:
  I n the present s t u d y virus grown in BEK-1 cells was used. F u r t h e r m o r e , the bovine sera had m a r k e d l y higher N T titers to CDCV t h a n H E V , while the porcine sera showed similar N T titers against b o t h viruses; NT titer ratio, ttEV/CDCV, ranged from 1:64 to 1:4096 with bovine sera and from 1:1/4 to 1 : 16 with porcine sera.


id: cord-265201-ab67pnct
author: Sugiyama, K.
date: 1980
extension: .txt
mime: text/plain
words: 3277
sentence: 187
flesch: 64
cache: cache/cord-265201-ab67pnct.txt
txt: txt/cord-265201-ab67pnct.txt
title:
  Hemagglutination and structural polypeptides of a new coronavirus associated with diarrhea in infant mice

summary:
  h R D E a t indicated concentration, dissolved in 0.01 M Ca-Borate buffer (pH 7.2), at 37 ° C for 60 minutes, after which t h e cells were w a s h a t e d with t h e R D E Fig. 2 .


id: cord-278388-lzvtgwox
author: Hasoksuz, M.
date: 2014-05-20
extension: .txt
mime: text/plain
words: 2365
sentence: 95
flesch: 54
cache: cache/cord-278388-lzvtgwox.txt
txt: txt/cord-278388-lzvtgwox.txt
title:
  Antigenic variation among bovine enteric coronaviruses (BECV) and bovine respiratory coronaviruses (BRCV) detected using monoclonal antibodies

summary:
  A rotavirus Bovine coronavirus respiratory infections in feedlot cattle Coronavirus infection of the bovine respiratory tract Characterization of monoclonal antibodies to bovine enteric coronavirus and antigenic variation among the Quebec isolates Characterization of monoclonal antibodies to the hemagglutinin-esterase glycoprotein of a bovine coronavirus associated with winter dysentery and cross-reactivity to field isolates Studies on the relationship between coronavirus from the intestinal and respiratory tracts of calves Winter dysentery in dairy herds: electron microscopic and serological evidence of an association with coronavirus infection Enteropathogenic coronaviruses The S protein of bovine coronavirus is a hemagglutinin recognizing 9-0-acetylated sialic acid as a receptor determinant Antigenic variation among transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus strains detected with monoclonal antibodies to the S protein of TGEV Antigenic and biological comparisons of bovine coronaviruses derived from neonatal calf diarrhea and winter dysentry of adult cattle Isolation of coronavirus from feces and nasal swabs of calves with diarrhea Monoclonal antibodies to a virulent strain of transmissible gastroenteritis virus: comparison of reactivity with virulent and attenuated virus The hemagglutinin/esterase glycoprotein of bovine virulent and avirulent coronavirus: sequence and functional comparison between strains Although some biologic and antigenic differences between BECV strains have been detected, it is unclear if these differences are distinctive between BECV (CD, WD) and BRCV strains, and if such differences can be used to differentiate and identify the sources of individual strains.


id: cord-272955-kkkrkgg1
author: Belsy, Acosta
date: 2009-03-12
extension: .txt
mime: text/plain
words: 4225
sentence: 191
flesch: 35
cache: cache/cord-272955-kkkrkgg1.txt
txt: txt/cord-272955-kkkrkgg1.txt
title:
  Molecular characterization of adenoviral infections in Cuba: report of an unusual association of species D adenoviruses with different clinical syndromes

summary:
  Rapid and sensitive diagnosis of human adenovirus infections by a generic polymerase chain reaction Outcome and clinical course of 100 patients with adenovirus infection following bone marrow transplantation Family Adenoviridae Infections in 18, 000 infants and children in a controlled study of respiratory tract disease. This research identified 49 confirmed cases of human adenovirus infection by PCR and/or viral culture.


id: cord-004749-wyzb8v4a
author: Forsyth, M.
title: Rhinovirus detection using probes from the 5′ and 3′ end of the genome
date: 1989
extension: .txt
mime: text/plain
words: 2581
sentence: 103
flesch: 54
cache: cache/cord-004749-wyzb8v4a.txt
txt: txt/cord-004749-wyzb8v4a.txt
summary:
  Table 3 shows the percentage of rhinovirus serotypes detected by each probe according to the strength o A hybridization with different probes show a different relationship between rhinovirus serotypes from that based an other properties.


id: cord-280865-shwxhak9
author: Zhang, Dan
date: 2018-06-30
extension: .txt
mime: text/plain
words: 2550
sentence: 87
flesch: 43
cache: cache/cord-280865-shwxhak9.txt
txt: txt/cord-280865-shwxhak9.txt
title:
  Clinical evaluation of a panel of multiplex quantitative real-time reverse transcription polymerase chain reaction assays for the detection of 16 respiratory viruses associated with community-acquired pneumonia

summary:
  II RV16 and Seeplex RV12 ACE assays for the detection of respiratory viruses Evaluation of the AdvanSure real-time RT-PCR compared with culture and Seeplex RV15 for simultaneous detection of respiratory viruses Clinical evaluation of a single-tube multiple RT-PCR assay for the detection of 13 common virus types/ subtypes associated with acute respiratory infection A two-tube multiplex reverse transcription PCR assay for simultaneous detection of sixteen human respiratory virus types/subtypes Detection of intergenic non-coding RNAs expressed in the main developmental stages in Drosophila melanogaster Added value of an oropharyngeal swab in detection of viruses in children hospitalized with lower respiratory tract infection Comparison of automated microarray detection with real-time PCR assays for detection of respiratory viruses in specimens obtained from children Comparison of fast-track diagnostics respiratory pathogens multiplex real-time RT-PCR assay with in-house singleplex assays for comprehensive detection of human respiratory viruses Resequencing microarray probe design for typing genetically diverse viruses: human rhinoviruses and enteroviruses Parainfluenza Virus Types 1, 2, and 3 in pediatric patients with acute respiratory infections in Beijing during Epidemiology and clinical presentation of the four human parainfluenza virus types Seasonal trends of human parainfluenza viral infections: United States Outbreak of pneumonia in a long-term care facility: antecedent human parainfluenza virus 1 infection may predispose to bacterial pneumonia Epidemiology and clinical characteristics of human coronaviruses OC43, 229E, NL63, and HKU1: a study of hospitalized children with acute respiratory tract infection in Guangzhou, China Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method We acknowledge the Children's Hospital, Zhejiang University School of Medicine, and the Center for Disease Control and Prevention of Zhejiang province for providing sputum. The mqRT-PCR assay performed comparably with the two-tube assay for most viruses, offering the advantages of quantitative analysis, easier performance, lower susceptibility to contamination, and shorter turnaround time in laboratories equipped with conventional real-time PCR instrumentation, and it could therefore be a valuable tool for routine surveillance of respiratory virus infections in China.


id: cord-285329-62yafd2d
author: Tsunemitsu, H.
date: 1995
extension: .txt
mime: text/plain
words: 2469
sentence: 84
flesch: 46
cache: cache/cord-285329-62yafd2d.txt
txt: txt/cord-285329-62yafd2d.txt
title:
  Antigenic and biological comparisons of bovine coronaviruses derived from neonatal calf diarrhea and winter dysentery of adult cattle

summary:
  Titers which differed by 16-tbld or greater with homologous titers are underlined bCD Calf diarrhea, WD winter dysentery of adult cattle were observed among CD BCV strains. These results suggest that some antigenic and biological diversity exists among BCV strains, but these variations were unrelated to the clinical source of the strains; i.e. CD or WD. which were concentrated approximately 100-to 200-fold.


id: cord-004727-9sniu39j
author: Fennestad, K. L.
title: Pleural effusion disease in rabbits: Observations on viraemia, immunity and transmissibility
date: 1981
extension: .txt
mime: text/plain
words: 3049
sentence: 147
flesch: 52
cache: cache/cord-004727-9sniu39j.txt
txt: txt/cord-004727-9sniu39j.txt
summary:
  Accepting only these four deaths as caused by PEDV, the time of death was considerably delayed in baby rabbits as compared with older animals. The lack of cross-infection by contact between baby rabbits before and after weaning indicates that direct transmission of PED is probably a rare occurrence.


id: cord-004732-mgzmzeyr
author: Olofsson, S.
date: 1983
extension: .txt
mime: text/plain
words: 3935
sentence: 232
flesch: 59
cache: cache/cord-004732-mgzmzeyr.txt
txt: txt/cord-004732-mgzmzeyr.txt
title:
  Populations of herpes simplex virus glycoprotein gC with and without affinity for the N-acetyl-galactosamine specific lectin ofHelix pomatia

summary:
  The subfraction of gC demonstrating affinity for HPA as well as gC devoid of HPA binding capacity both revealed affinity for Con A. Only 5 per cent of the initially non-reactive fraction of gC became reactive to HPA after the treatments, suggesting that masking of penultimate N-acetylgalactosamine by sialic acid was not a main reason for lack of HPA affinity.


id: cord-285429-vmnj25b5
author: Saikruang, Wilaiporn
title: Detection of diarrheal viruses circulating in adult patients in Thailand
date: 2014-07-31
extension: .txt
mime: text/plain
words: 2190
sentence: 91
flesch: 46
cache: cache/cord-285429-vmnj25b5.txt
txt: txt/cord-285429-vmnj25b5.txt
summary:
  Since epidemiological information about gastroenteritis viruses in adults is limited, it is important to continue further surveillance, which may provide a better understanding of the whole picture of gastroenteritis virus epidemiology in the adult population. The relatively low rate of diarrheal virus detection in adults with diarrhea in this study suggests that acute gastroenteritis in adults in this area may be caused by other pathogens.


id: cord-261036-zdhg4axx
author: Shirato, Kazuya
title: Enhanced cell fusion activity in porcine epidemic diarrhea virus adapted to suckling mice
date: 2010-09-09
extension: .txt
mime: text/plain
words: 3339
sentence: 143
flesch: 56
cache: cache/cord-261036-zdhg4axx.txt
txt: txt/cord-261036-zdhg4axx.txt
summary:
  In our study, both mouse-adapted and non-adapted MK strains of PEDV could infect and grow in suckling mouse brains, suggesting that a receptor molecule utilized by both viruses exists in suckling mouse brain. In the present study, we isolated a strain of PEDV that was more virulent than the original tissue-culture-adapted virus after passage through mouse brain cells.


id: cord-280905-g2vcy9ea
author: Carstens, E. B.
date: 2009-06-03
extension: .txt
mime: text/plain
words: 1057
sentence: 47
flesch: 46
cache: cache/cord-280905-g2vcy9ea.txt
txt: txt/cord-280905-g2vcy9ea.txt
title:
  Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2008)

summary:
  As a means of promoting contact between ICTV and its National Members and to ensure that lists of members are up to date, member societies of IUMS are obliged to either renew ICTV National Members or replace them every three years. key: cord-280905-g2vcy9ea authors: Carstens, E. B.; Ball, L. A. title: Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2008) date: 2009-06-03 journal: Arch Virol DOI: 10.1007/s00705-009-0400-2 sha: doc_id: 280905 cord_uid: g2vcy9ea In accordance with the Statutes of the International Committee of Taxonomy of Viruses (ICTV), the final stage in the process of making changes to the Universal Scheme of Virus Classification is the ratification of taxonomic proposals by ICTV Members.


id: cord-267446-rpv19oy6
author: Park, Jung-Eun
date: 2011-06-12
extension: .txt
mime: text/plain
words: 4088
sentence: 140
flesch: 39
cache: cache/cord-267446-rpv19oy6.txt
txt: txt/cord-267446-rpv19oy6.txt
title:
  Receptor-bound porcine epidemic diarrhea virus spike protein cleaved by trypsin induces membrane fusion

summary:
  key: cord-267446-rpv19oy6 authors: Park, Jung-Eun; Cruz, Deu John M.; Shin, Hyun-Jin title: Receptor-bound porcine epidemic diarrhea virus spike protein cleaved by trypsin induces membrane fusion date: 2011-06-12 journal: Arch Virol DOI: 10.1007/s00705-011-1044-6 sha: doc_id: 267446 cord_uid: rpv19oy6 Porcine epidemic diarrhea virus (PEDV) infection in Vero cells is facilitated by trypsin through an undefined mechanism. The present study describes the mode of action of trypsin in enhancing PEDV infection in Vero cells during different stage of the virus life cycle.


id: cord-004742-5movyeb4
author: García-Luque, I.
date: 1993
extension: .txt
mime: text/plain
words: 4311
sentence: 148
flesch: 47
cache: cache/cord-004742-5movyeb4.txt
txt: txt/cord-004742-5movyeb4.txt
title:
  The nucleotide sequence of the coat protein genes and 3′ non-coding regions of two resistance-breaking tobamoviruses in pepper shows that they are different viruses

summary:
  Mutant viral RNAs synthesized in vitro show altered aminoacylation and replicase template activities An unusual strain of tobacco mosaic virus from pepper A classification of the tobamoviruses based on comparisons among their 126 K proteins Sequence and structure at the genome 3'end of the U2-strain of tobacco mosaic virus, a histidine-accepting tobamovirus Characterization of a Spanish strain of pepper mild mottle virus (PMMV-S) and its relationship to other tobamoviruses Tobamovirus classification Nucleotide sequence of tobacco mosaic virus RNA Some viruses affecting tomatoes and peppers in Argentina Resistance to tobacco mosaic virus in Capsicum, with reference to the Sansum latent strain A simple and very efficient method for generating cDNA libraries The complete nucleotide sequence of tobacco rattle virus RNA-1 Fast and sensitive multiple sequence alignments on a microcomputer Two pepper resistance-breaking tobamoviruses 87 Clustal V: improved software for multiple sequence alignments Molecular cloning, sequencing and expression in Escherichia coli of the odontoglossum ringspot virus coat protein gene Domains in viroids: evidence of intermolecular RNA rearrangements and their contribution to viroid evolution The mechanism of RNA recombination in poliovirus A point mutation in the tobacco mosaic virus capsid protein gene induces hypersensitivity in Nicotiana sylvestris High-frequency RNA recombination of murine coronaviruses Molecular cloning: a laboratory manual Similarities among plant viruses (+) and ( -) RNA termini imply a common ancestry with promoters of eukaryotic tRNAs Occurrence of pepper mild mottle virus in pepper cuttivars from Italy and Spain Prediction of RNA secondary structure, including pseudoknotting, by computer simulation Sequence of cowpea chlorotic mottle virus RNAs 2 and 3 and evidence of a recombination event during bromovirus evolution A tobamovirus causing heavy losses in protected pepper crops in Spain Nucleotide sequence of the genomic RNA of pepper mild mottle virus, a resistance-breaking tobamovirus in pepper Correlation of co-ordinated amino 86 I acid substitutions with function in viruses related to tobacco mosaic virus Nucleotide sequences of 5' and 3' non-coding regions of pepper mild mottle virus strain S RNA Evolutionary changes in TMV pepper strains as a result of repeated host passages Strains of TMV and genes for resistance in Capsicum Genetic recombination between RNA components of a multipartite plant virus Modulation of replication, aminoacylation and adenylation in vitro and infectivity in vivo of BMV RNAs containing deletions within the multifunctional 3' end Nucleotide sequence analysis of the movement genes of resistance breaking strains of tomato mosaic virus Recombination between satellite RNAs of turnip crinkle virus The amino acid composition of the coat protein of a tobamovirus from an Australian Capsicum crop A new pepper strain of tomato mosaic virus Point mutations in the coat protein gene of tobacco mosaic virus induce hypersensitivity in Nicotiana sylvestris


id: cord-285547-7m3dh8hu
author: Nomura, Naoki
date: 2011-11-09
extension: .txt
mime: text/plain
words: 3289
sentence: 108
flesch: 42
cache: cache/cord-285547-7m3dh8hu.txt
txt: txt/cord-285547-7m3dh8hu.txt
title:
  Characterization of avian influenza viruses isolated from domestic ducks in Vietnam in 2009 and 2010

summary:
  H9N2 influenza viruses possessing H5N1-like internal genomes continue to circulate in poultry in southeastern China Characterization of the pathogenicity of members of the newly established H9N2 influenza virus lineages in Asia Coinfection of avian influenza virus (H9N2 subtype) with infectious bronchitis live vaccine Universal primer set for the full-length amplification of all influenza A viruses Perpetuation of influenza A viruses in Alaskan waterfowl reservoirs Genetic characterization of H1 avian influenza viruses isolated from migratory birds and domestic ducks in Korea Phylogenetic and molecular characterization of H9N2 influenza isolates from chickens in Northern China from Isolation and characterization of influenza a viruses from wild free-flying ducks in Hokkaido Biological activity of monoclonal antibodies to operationally defined antigenic regions on the hemagglutinin molecule of A/Seal/Massachusetts/1/80 (H7N7) influenza virus Potential for transmission of avian influenza viruses to pigs Genetic relatedness of H6 subtype avian influenza viruses isolated from wild birds and domestic ducks in Korea and their pathogenicity in animals Co-infection of Staphylococcus aureus or Haemophilus paragallinarum exacerbates H9N2 influenza A virus infection in chickens H2N5 influenza virus isolates from terns in Australia: genetic reassortants between those of the Eurasian and American lineages Avian-to-human transmission of H9N2 subtype influenza A viruses: relationship between H9N2 and H5N1 human isolates Phylogenetic analysis of the hemagglutinin genes of twenty-six avian influenza viruses of subtype H9N2 isolated from chickens in China during H9N2 influenza viruses prevalent in poultry in China presumed to be the donor of the internal protein genes of the H5N1 Hong Kong/97 virus The influenza virus gene pool in a poultry market in south central China Phylogenic analysis of the M genes of influenza viruses isolated from free-flying water birds from their Northern Territory to Hokkaido Active reassortment of H9 influenza viruses between wild birds and live-poultry markets in Korea Isolation and pathotyping of H9N2 avian influenza viruses in Indian poultry Isolation and characterization of avian influenza viruses, including highly pathogenic H5N1, from poultry in live bird markets in Hanoi Precursor genes of future pandemic influenza viruses are perpetuated in ducks nesting in Siberia Rapid evolution of low-pathogenic H9N2 avian influenza viruses following poultry vaccination programmes Human infection with influenza H9N2 Role of quail in the interspecies transmission of H9 influenza Genotypic evolution and antigenic drift of H9N2 influenza viruses in China from Isolation and identification of swine influenza recombinant A/Swine/Shandong/1/2003(H9N2) virus The genesis and evolution of H9N2 influenza viruses in poultry from southern China Characterization of a non-pathogenic H5N1 influenza virus isolated from a migratory duck flying from Siberia in Hokkaido Evaluation of the reverse transcription loopmediated isothermal amplification (RT-LAMP) as a screening method for the detection of influenza viruses in the fecal materials of water birds Genetic diversity of H9N2 influenza viruses from pigs in China: a potential threat to human health?


id: cord-004733-i0a3igc7
author: Nagata, S.
date: 1992
extension: .txt
mime: text/plain
words: 5170
sentence: 228
flesch: 49
cache: cache/cord-004733-i0a3igc7.txt
txt: txt/cord-004733-i0a3igc7.txt
title:
  Identification of epitopes associated with different biological activities on the glycoprotein of vesicular stomatitis virus by use of monoclonal antibodies

summary:
  key: cord-004733-i0a3igc7 authors: Nagata, S.; Okamoto, Y.; Inoue, T.; Ueno, Y.; Kurata, T.; Chiba, J. title: Identification of epitopes associated with different biological activities on the glycoprotein of vesicular stomatitis virus by use of monoclonal antibodies date: 1992 journal: Arch Virol DOI: 10.1007/bf01309581 sha: doc_id: 4733 cord_uid: i0a3igc7 Thirteen monoclonal antibodies (MAbs) to the glycoprotein (G) of vesicular stomatitis virus (VSV) serotype Indiana were prepared and examined for their effects on various biological activities of VSV, including in vitro infection, hemagglutination, adsorption to cells, and mediation of cell fusion. Monoclonal antibodies to nonneutralizing and cross-reactive epitope of Indiana and New Jersey serotypes Antigenic determinants of vesicular stomatitis virus: analysis with antigenic variants Point mutations in glycoprotein gene of vesicular stomatitis virus (New Jersey serotype) selected by resistance to neutralization by epitope-specific monoclonal antibodies Spontaneous mutations leading to antigenic variations in the glycoproteins of vesicular stomatitis virus field isolates pH-dependent hemolysis and cell fusion of rhabdoviruses Virus entry into animal cells Pathway of vesicular stomatitis virus entry leading to infection Transepithelial transport of a viral membrane glycoprotein implanted into the apical plasma membrane of Madin-Darby canine kidney cells.


id: cord-032801-b2ncmkjg
author: Song, Jie
date: 2020-09-29
extension: .txt
mime: text/plain
words: 4954
sentence: 194
flesch: 43
cache: cache/cord-032801-b2ncmkjg.txt
txt: txt/cord-032801-b2ncmkjg.txt
title:
  Transcriptome analysis following enterovirus 71 and coxsackievirus A16 infection in respiratory epithelial cells

summary:
  For gene expression analysis, the expression level of each gene was calculated by determining the number of reads and was further normalized by a variation of the FPKM method. RNA sequencing (RNA-Seq) can be used to investigate differences in gene expression at a genome-wide level.


id: cord-299342-l8ugjou9
author: Yaling, Zhou
date: 1988
extension: .txt
mime: text/plain
words: 2980
sentence: 114
flesch: 44
cache: cache/cord-299342-l8ugjou9.txt
txt: txt/cord-299342-l8ugjou9.txt
title:
  Porcine epidemic diarrhea virus (CV 777) and feline infectious peritonitis virus (FIPV) are antigenically related

summary:
  key: cord-299342-l8ugjou9 authors: Yaling, Zhou; Ederveen, J.; Egberink, H.; Pensaert, M.; Horzinek, M. C. title: Porcine epidemic diarrhea virus (CV 777) and feline infectious peritonitis virus (FIPV) are antigenically related date: 1988 journal: Arch Virol DOI: 10.1007/bf01315563 sha: doc_id: 299342 cord_uid: l8ugjou9 Using gut sections from pigs infected with porcine epidemic diarrhea virus (strain CV 777) and ascitic fluid from cats which had succumbed to feline infectious peritonitis (FIP), a weak cross reaction was found by immunofluorescence. We have confirmed the finding of cross reactions within one group, namely between transmissible gastroenteritis virus (TGEV) of swine, FIPV and canine enteric coronavirus, and showed that common determinants are present on all three structural polypeptides [7] .


id: cord-284087-g2jfnxja
author: Falcone, Valeria
date: 2013-02-09
extension: .txt
mime: text/plain
words: 3424
sentence: 144
flesch: 46
cache: cache/cord-284087-g2jfnxja.txt
txt: txt/cord-284087-g2jfnxja.txt
title:
  Influenza virus A(H1N1)pdm09 hemagglutinin polymorphism and associated disease in southern Germany during the 2010/11 influenza season

summary:
  Understanding the evolution of influenza virus is crucial to determine pathogenesis, vaccine efficacy, and resistance to antiviral drugs. Hemagglutinin (HA) and neuraminidase (NA) represent two major surface glycoproteins of influenza virus.


id: cord-302871-x3mjov5l
author: Ribeiro, Juliane
title: Extra-intestinal detection of canine kobuvirus in a puppy from Southern Brazil
date: 2016-11-25
extension: .txt
mime: text/plain
words: 2593
sentence: 99
flesch: 39
cache: cache/cord-302871-x3mjov5l.txt
txt: txt/cord-302871-x3mjov5l.txt
summary:
  key: cord-302871-x3mjov5l authors: Ribeiro, Juliane; Headley, Selwyn Arlington; Diniz, Jaqueline Assumpção; Pereira, Alfredo Hajime Tanaka; Lorenzetti, Elis; Alfieri, Amauri Alcindo; Alfieri, Alice Fernandes title: Extra-intestinal detection of canine kobuvirus in a puppy from Southern Brazil date: 2016-11-25 journal: This study presents the pathological, immunohistochemical, and molecular findings associated with the extra-intestinal detection of canine kobuvirus (CaKV) in a 5-month-old Chihuahua puppy, that had a clinical history of bloody-tinged feces.


id: cord-299763-ttb7o8lv
author: Choi, Jeong-Won
date: 2016-06-01
extension: .txt
mime: text/plain
words: 2621
sentence: 92
flesch: 41
cache: cache/cord-299763-ttb7o8lv.txt
txt: txt/cord-299763-ttb7o8lv.txt
title:
  Molecular characteristics of a novel strain of canine minute virus associated with hepatitis in a dog

summary:
  Although liver degeneration in canines has also been described at post-mortem examination of a pup infected with MVC [6] , and a novel bocavirus (KC580640) that was highly divergent from known MVC strains has been isolated from canine liver [11] , hepatitis with evidence of intranuclear inclusion bodies that correspond to MVC infection has not yet been reported. ORF1 of the 15D009 strain encodes a 776-aa non-structural (NS) protein, which is 2-60 aa longer than the NS protein of other MVC strains.


id: cord-295409-7l0pglef
author: Percy, D.
title: Replication of sialodacryoadenitis virus in mouse L-2 cells
date: 1989
extension: .txt
mime: text/plain
words: 3069
sentence: 151
flesch: 51
cache: cache/cord-295409-7l0pglef.txt
txt: txt/cord-295409-7l0pglef.txt
summary:
  Cell cultures were grown in Eagle's minimal essential medium (Gibco/BRL Inc., Burlington, Ontario) containing 200 U/ml penicillin, 80 gg/ml streptomycin and 0.05 gg/ml gentamicin supplemented with 5% (L-2; L-929) or 10% (LBC) fetal bovine serum. Despite the fact the L-2 cell-adapted SDAV presumably underwent some alteration(s) to allow high levels of expression in cell culture, the passage of the virus grown in vitro retained the ability to produce lesions typical of SDA in intranasally-inoculated rats.


id: cord-293945-gyb9mjb5
author: Chai, Weidong
date: 2012-11-28
extension: .txt
mime: text/plain
words: 4313
sentence: 162
flesch: 37
cache: cache/cord-293945-gyb9mjb5.txt
txt: txt/cord-293945-gyb9mjb5.txt
title:
  Antiviral effects of a probiotic Enterococcus faecium strain against transmissible gastroenteritis coronavirus

summary:
  To assess the potential prophylactic or therapeutic effect of the probiotic bacteria E. faecium on TGEV infection, increasing concentrations of probiotic E. faecium bacteria were added to ST cells before, concomitantly with, or after TGEV infection for a short period of time, and cell viability as well as virus titers in the culture medium were quantitatively assessed later after long-term incubation. We have studied the protective effects of the probiotic Enterococcus faecium NCIMB 10415 (E. faecium), which is approved as a feed additive in the European Union, against TGEV infection.


id: cord-287275-vwyny1vt
author: Zhang, Meng-Jia
date: 2018-10-30
extension: .txt
mime: text/plain
words: 5204
sentence: 223
flesch: 52
cache: cache/cord-287275-vwyny1vt.txt
txt: txt/cord-287275-vwyny1vt.txt
title:
  Genomic characterization and pathogenicity of porcine deltacoronavirus strain CHN-HG-2017 from China

summary:
  A nucleotide sequence alignment showed that the whole genome of CHN-HG-2017 is 97.6%-99.1% identical to other PDCoV strains. Similar to other PDCoV strains, the complete genome sequence of CHN-HG-2017 is 25,399 nt in length, consisting of 5′ UTR-1ab-S-E-M-NS6-N-NS7-3′ UTR, and predicted transcription regulatory sequences (TRSs) were located at the 5′ end of each gene with a highly conserved core sequence of 5′ -ACCAC-3′ (Table 1) .


id: cord-283710-55m16q7c
author: Wo, Ying
title: Epidemical features of HAdV-3 and HAdV-7 in pediatric pneumonia in Chongqing, China
date: 2014-12-12
extension: .txt
mime: text/plain
words: 2895
sentence: 117
flesch: 41
cache: cache/cord-283710-55m16q7c.txt
txt: txt/cord-283710-55m16q7c.txt
summary:
  In the United States and southern Ontario from 2004 to 2006, HAdV-3 accounted for 34.6 % of HAdV respiratory tract infection in civilians and 2.6 % among military trainees, while HAdV-7 accounted for only 5/581 (0.9 %) of clinical HAdV respiratory isolates in military facilities and 48/1653 (2.9 %) of isolates in civilian settings From the cohort, patients with pneumonia were selected to analyze the epidemiological and clinical features of HAdV infection.


id: cord-257859-9hmrt96h
author: Di Martino, Barbara
title: Molecular evidence of kobuviruses in free-ranging red foxes (Vulpes vulpes)
date: 2014-01-23
extension: .txt
mime: text/plain
words: 1680
sentence: 68
flesch: 49
cache: cache/cord-257859-9hmrt96h.txt
txt: txt/cord-257859-9hmrt96h.txt
summary:
  The markers indicate the sequences detected in this study Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses Prevalence and genetic diversity of Aichi virus strains in stool samples from community and hospitalized patients Molecular epidemiology of canine adenovirus type 1 and type 2 in free-ranging red foxes (Vulpes vulpes) in Italy Antigenic analysis of canine parvovirus strains isolated in Italy Phylogeny and prevalence of kobuviruses in dogs and cats in the UK Detection and genetic characterization of feline kobuviruses A real-time PCR assay for rapid detection and quantitation of canine parvovirus type 2 in the feces of dogs Canine kobuviruses in diarrhoeic dogs in Italy BioEdit: a user-friendly biological sequence alignment and analysis program for Windows 95/98/NT Aichi virus infection in elderly people in Sweden Aichi virus infection in children with acute gastroenteritis in Finland Characterization of a canine homolog of human Aichi virus MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment Viruses in diarrhoeic dogs include novel kobuviruses and sapoviruses Canine distemper epizootic among red foxes Novel norovirus in dogs with diarrhea The fecal viral flora of wild rodents Development of a nested PCR assay for the detection of canine coronavirus Candidate new species of kobuvirus in porcine hosts Complete nucleotide and amino acid sequences and genetic organization of porcine kobuvirus, a member of a new species in the genus Kobuvirus, family Picornaviridae Detection of Aichi virus shedding in a child with enteric and extraintestinal symptoms in Hungary Porcine kobuvirus in wild boars (Sus scrofa) Metagenomic analysis of the ferret fecal viral flora Survey on viral pathogens in wild red foxes (Vulpes vulpes) in Germany with special emphasis on parvoviruses and analysis of a DNA sequence from a red fox parvovirus Rational optimization of generic primers used for Norwalk-like virus detection by reverse transcriptase polymerase chain reaction Isolation and characterization of a new species of kobuvirus associated with cattle Isolation of cytopathic small round viruses with BS-C-1 cells from patients with gastroenteritis Detection of canine coronaviruses genotype I and II in raised Canidae animals in China Acknowledgments This work was financed by grants from the University of Teramo, Italy, and from the Italian Ministry of University and Research. In the present study, we detected kobuviruses in freeranging red foxes with a prevalence rate of 14.7 % (5/34).


id: cord-305859-vt8vwo3y
author: Jung, Kwonil
date: 2017-04-03
extension: .txt
mime: text/plain
words: 3251
sentence: 141
flesch: 52
cache: cache/cord-305859-vt8vwo3y.txt
txt: txt/cord-305859-vt8vwo3y.txt
title:
  Calves are susceptible to infection with the newly emerged porcine deltacoronavirus, but not with the swine enteric alphacoronavirus, porcine epidemic diarrhea virus

summary:
  Our study did not identify which type of cells in the intestines of inoculated calves could be the target for PDCoV replication, resulting in fecal shedding. On the other hand, none of the Gn calves inoculated with PEDV shed detectable PEDV RNA in the feces at PIDs 1-9 (calves #6 and #7) and PIDs 1-17 (calf #5).


id: cord-004775-foaf3vyl
author: Weiss, Marianne
title: The proposed family toroviridae: Agents of enteric infections
date: 1987
extension: .txt
mime: text/plain
words: 3949
sentence: 189
flesch: 52
cache: cache/cord-004775-foaf3vyl.txt
txt: txt/cord-004775-foaf3vyl.txt
summary:
  Pronase and B. subtilis proteinase reduced BEV virus infectivity whereas treatment with trypsin and chymotrypsin remained without effect. Bacilliform viruses with a rodlike core are On the right electron mierographs of BEV particles, on the left schematic interpretations of the viral structures seen in the corresponding photographs are shown, a Virion with a toroidal core within a circular particle out, line.


id: cord-286794-adbxzgvs
author: Du, Juan
date: 2019-03-16
extension: .txt
mime: text/plain
words: 1183
sentence: 47
flesch: 48
cache: cache/cord-286794-adbxzgvs.txt
txt: txt/cord-286794-adbxzgvs.txt
title:
  Identification and complete genome characterization of human enterovirus 117 from a child with pneumonia in China

summary:
  The VP1 sequence of the CQ6747 isolate is 96.5%-97.4% identical to those of other EV-C117 isolates, and other genome regions displayed >90% sequence identity to EV-C117. key: cord-286794-adbxzgvs authors: Du, Juan; Zhu, Teng; Zhuang, Lu; Zhang, Pan-He; Zhang, Xiao-Ai; Lu, Qing-Bin; Liu, Wei title: Identification and complete genome characterization of human enterovirus 117 from a child with pneumonia in China date: 2019-03-16 journal: Arch Virol DOI: 10.1007/s00705-019-04196-y sha: doc_id: 286794 cord_uid: adbxzgvs In this study, human enterovirus C117 (EV-C117) was detected in a 3-month-old boy diagnosed with pneumonia in China.


id: cord-294218-v4gjabp3
author: Dea, S.
date: 1989
extension: .txt
mime: text/plain
words: 5303
sentence: 214
flesch: 45
cache: cache/cord-294218-v4gjabp3.txt
txt: txt/cord-294218-v4gjabp3.txt
title:
  Intracellular synthesis and processing of the structural glycoproteins of turkey enteric coronavirus

summary:
  We found that TCV had a modest inhibitory effect on cell protein synthesis, making the analysis of virus-specific proteins difficult. By 12 hours, all four major TCVinduced polypeptides were present; they persisted until virus and host cell protein synthesis was reduced due to extensive cytopathic changes (between 48 and 72 hours post-infection).


id: cord-283525-kvcqayl4
author: Wei, Zhan-Yong
title: Nitric oxide inhibits the replication cycle of porcine parvovirus in vitro
date: 2009-05-13
extension: .txt
mime: text/plain
words: 2374
sentence: 85
flesch: 42
cache: cache/cord-283525-kvcqayl4.txt
txt: txt/cord-283525-kvcqayl4.txt
summary:
  Although this reduction in viral replication is seen with NO itself, it is not certain whether the antiviral effects of SNAP or LA are actually due to some other NOrelated species. However, further study is needed to identify the host and viral targets of NO, and the exact mechanism by which NO inhibits viral replication in vitro and in vivo remains to be determined.


id: cord-004840-4rbrzv5o
author: Choudhary, Manohar Lal
date: 2013-08-09
extension: .txt
mime: text/plain
words: 3382
sentence: 149
flesch: 47
cache: cache/cord-004840-4rbrzv5o.txt
txt: txt/cord-004840-4rbrzv5o.txt
title:
  Development of real-time RT-PCR for detection of human metapneumovirus and genetic analysis of circulating strains (2009-2011) in Pune, India

summary:
  A newly discovered human pneumovirus isolated from young children with respiratory tract disease Children with respiratory disease associated with metapneumovirus in Hong Kong Human metapneumovirus infection in Japanese children First detection of human metapneumovirus in children with acute respiratory infection in India: a preliminary report Human metapneumovirus genetic variability Genetic diversity of human Real-time RT-PCR for human metapneumovirus 223 metapneumovirus over 4 consecutive years in Australia Genetic variability and circulation pattern of human metapneumovirus isolated in Italy over five epidemic seasons Detection and genetic diversity of human metapneumovirus in hospitalized children with acute respiratory infections in Southwest China Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups Ruuskanen O (2002) Metapneumovirus and acute wheezing in children Human metapneumovirus infections in young and elderly adults Human metapneumovirus in severe respiratory syncytial virus bronchiolitis Human metapneumovirus among children hospitalized for acute respiratory illness Seasonality and clinical features of human metapneumovirus infection in children in Northern Alberta Epidemiology of human metapneumovirus The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience Study of human metapneumovirus-associated lower respiratory tract infections in Egyptian adults An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility for the elderly in Oregon Rates of hospitalizations for respiratory syncytial virus, human metapneumovirus, and influenza virus in older adults Severe metapneumovirus infections among immunocompetent and immunocompromised patients admitted to hospital with respiratory infection Humane metapneumovirus (HMPV) associated pulmonary infections in immunocompromised adults-initial CT findings, disease course and comparison to respiratory-syncytialvirus (RSV) induced pulmonary infections Comparative evaluation of realtime PCR assays for detection of the human metapneumovirus Molecular assays for detection of human metapneumovirus Real-time reverse transcriptase PCR assay for detection of human metapneumoviruses from all known genetic lineages Detection of human metapneumovirus RNA sequences in nasopharyngeal aspirates of young French children with acute bronchiolitis by real-time reverse transcriptase PCR and phylogenetic analysis Detection and quantification of human metapneumovirus in pediatric specimens by real-time RT-PCR Diagnosis and epidemiological studies of human metapneumovirus using real-time PCR Detection and characterisation of human metapneumovirus from children with acute respiratory symptoms in northwest England Real-time reverse transcriptase PCR assay for improved detection of human metapneumovirus Analysis of the genomic sequence of a human metapneumovirus Antigenic and genetic variability of human metapneumoviruses Global genetic diversity of human metapneumovirus fusion gene Novel human metapneumovirus sublineage Genetic variability of attachment (G) and Fusion (F) protein genes of human metapneumovirus strains circulating during Detection and genetic diversity of human metapneumovirus in hospitalized children with acute respiratory infections in India Genomic analysis of four human metap-neumovirus prototypes Development of a multiplex one step RT-PCR that detects eighteen respiratory viruses in clinical specimens and comparison with real time RT-PCR Molecular epidemiology of human metapneumovirus from Phylogenetic analysis of human metapneumovirus from New York State patients during February through Genotype variability and clinical features of human metapneumovirus isolated from Korean children Human metapneumovirus strains circulating in Latin America Human metapneumovirus-associated hospital admissions over five consecutive epidemic seasons: evidence for alternating circulation of different genotypes Evolutionary Dynamics Analysis of Human Metapneumovirus Subtype A2: Genetic Evidence for Its Dominant Epidemic Real-time RT-PCR for human metapneumovirus Human metapneumovirus (HMPV), first isolated from children with acute lower-respiratory-tract infections (ALRTI) in the Netherlands in 2001, is an enveloped, non-segmented RNA virus that belongs to the family Paramyxoviridae and the genus Metapneumovirus


id: cord-004849-d64hnqkh
author: Choi, C. S.
title: Temperature dependent replication of porcine parvovirus isolates
date: 1989
extension: .txt
mime: text/plain
words: 2342
sentence: 91
flesch: 42
cache: cache/cord-004849-d64hnqkh.txt
txt: txt/cord-004849-d64hnqkh.txt
summary:
  Similar patterns of cell associated virus were detected from both NADL-8 and NADL-2 infected ceils at the 3 temperatures (Fig. 2 a, b) , whereas marked differences were again observed for Kresse and KBSH-infected cells (Fig. 2 c, d) . The pattern of cell associated virus from Kresse and KBSH-infected cells was similar to that described above for .


id: cord-280781-u3wd27rn
author: Stohlman, S. A.
date: 1978
extension: .txt
mime: text/plain
words: 3511
sentence: 135
flesch: 44
cache: cache/cord-280781-u3wd27rn.txt
txt: txt/cord-280781-u3wd27rn.txt
title:
  Stability of neurotropic mouse hepatitis virus (JHM strain) during chronic infection of neuroblastoma cells

summary:
  To approach the study of possible mechanisms of chronic infection in vivo, persistence of JHM virus in vitro was established and studied. The :Nj cell line was established by infecting the mouse neuroblastoma N2A cells (17) with JHM virus at a multiplicity of infection (MOI) of 0.01.


id: cord-281410-y558a5jf
author: Akashi, H.
title: Propagation of the Kakegawa strain of bovine coronavirus in suckling mice, rats and hamsters
date: 1981
extension: .txt
mime: text/plain
words: 1124
sentence: 52
flesch: 54
cache: cache/cord-281410-y558a5jf.txt
txt: txt/cord-281410-y558a5jf.txt
summary:
  (4) reported that they had adapted the American strain of calf diarrhea coronavirus to suckling mouse brain. The Kakegawa strain of BCV used for mouse inoculation was at, the 10th passage level in primary bovine kidney cell cultures.


id: cord-302323-vvo8a4hp
author: Wang, Xiaobo
date: 2015-11-26
extension: .txt
mime: text/plain
words: 5009
sentence: 178
flesch: 47
cache: cache/cord-302323-vvo8a4hp.txt
txt: txt/cord-302323-vvo8a4hp.txt
title:
  Immunogenicity and antigenic relationships among spike proteins of porcine epidemic diarrhea virus subtypes G1 and G2

summary:
  The ELISA results indicated high cross-reactivity between the PAbs and the two types of PEDV S protein. The IFA results indicated that PEDV S protein was present in the cytoplasm of Vero E6 cells (Fig. 5A ).


id: cord-262505-1ufgwxxg
author: Lai, M. M. C.
title: Genetic heterogeneity of murine coronaviruses
date: 1983
extension: .txt
mime: text/plain
words: 2562
sentence: 115
flesch: 50
cache: cache/cord-262505-1ufgwxxg.txt
txt: txt/cord-262505-1ufgwxxg.txt
summary:
  Persistent infection with mouse hepatitis virus JHM strain in DBT ceil culture Isolation of low-virulent mouse hepatitis virus from feces in infected mouse breeding colony Isolation of low-virulent mouse hepatitis virus from nude mice with wasting syndrome and hepatitis Evolution of multiple genome mutations during long-term persistent infection by vesicular stomatitis virus Evolution of a coronavirus during persistent infection in vitro Pathology of diarrhea due to mouse hepatitis virus in the infant mouse Isolation of mouse hepatitis virus from infant mice with fatal diarrhea Hepatosplenic myelosis in naturally occurring mouse hepatitis virus infection in the nude mouse Mouse hepatitis virus A59: mRNA structure and genetic localization of the sequence divergence from hepatotropic strai~ ? No viruses of other genotypes were isolated, suggesting that MHV viruses are relatively stable during lyric infection, whereas persistent or latent infection in the-~euroblastoma cell line tends to select for various types of variants.


id: cord-269948-zfbu9646
author: Teo, Jeanette
date: 2011-04-19
extension: .txt
mime: text/plain
words: 3856
sentence: 154
flesch: 44
cache: cache/cord-269948-zfbu9646.txt
txt: txt/cord-269948-zfbu9646.txt
title:
  VereFlu™: an integrated multiplex RT-PCR and microarray assay for rapid detection and identification of human influenza A and B viruses using lab-on-chip technology

summary:
  key: cord-269948-zfbu9646 authors: Teo, Jeanette; Pietro, Patrizia Di; Biagio, Floriana San; Capozzoli, Monica; Deng, Yi-Mo; Barr, Ian; Caldwell, Natalie; Ong, Kian-Leong; Sato, Mitsuharu; Tan, Rosemary; Lin, Raymond title: VereFlu™: an integrated multiplex RT-PCR and microarray assay for rapid detection and identification of human influenza A and B viruses using lab-on-chip technology date: 2011-04-19 journal: Arch Virol DOI: 10.1007/s00705-011-0999-7 sha: doc_id: 269948 cord_uid: zfbu9646 Threatening sporadic outbreaks of avian influenza and the H1N1 pandemic of 2009 highlight the need for rapid and accurate detection and typing of influenza viruses. Therefore, the looming threat of pandemics from influenza viruses cannot be overlooked, and assays that enable rapid, accurate identification and subtyping of influenza viruses is pertinent for surveillance and outbreak management.


id: cord-282062-h9smg0w9
author: Takano, Tomomi
title: Novel single-stranded, circular DNA virus identified in cats in Japan
date: 2018-09-14
extension: .txt
mime: text/plain
words: 1945
sentence: 84
flesch: 48
cache: cache/cord-282062-h9smg0w9.txt
txt: txt/cord-282062-h9smg0w9.txt
summary:
  All 4 strains of FeSCV were circular DNA viruses containing a genome (Fig. 1B) . To our knowledge, no study has reported a gene encoding Cap or putative Cap of CRESS DNA virus generated by recombination with parasitic or bacterial genes.


id: cord-291707-dzmvjh7j
author: Tupper, G. T.
date: 1987
extension: .txt
mime: text/plain
words: 2793
sentence: 124
flesch: 53
cache: cache/cord-291707-dzmvjh7j.txt
txt: txt/cord-291707-dzmvjh7j.txt
title:
  Antigenic and biological diversity of feline coronaviruses: feline infectious peritonitis and feline enteritis virus

summary:
  The molecular weight of virus structural proteins was determined by using molecular weight standards (Sigma, St. Louis, MO). FIPV grows to higher titer, forms larger plaques and switches off host cell protein synthesis more effectively than FECV.


id: cord-004766-gvom0f13
author: Traavik, T.
title: Improvement of arbovirus HA antigens by treatment with a colloidal silica gel and sonication
date: 1977
extension: .txt
mime: text/plain
words: 2239
sentence: 98
flesch: 52
cache: cache/cord-004766-gvom0f13.txt
txt: txt/cord-004766-gvom0f13.txt
summary:
  HA titers in reciprocal values b Untreated The experiments described have demonstrated the ability of the colloidal silica gel Aerosil to absorb supposed HA inhibitory factors from virus antigen preparations. Rubella virus HA antigen and HB(s)Ag were adsorbed to the gel, and excluded from a preparation by treatment with Aerosil.


id: cord-283804-dje7qbps
author: Macnaughton, M. R.
title: The polypeptide composition of avian infectious bronchitis virus particles
date: 1977
extension: .txt
mime: text/plain
words: 2686
sentence: 145
flesch: 71
cache: cache/cord-283804-dje7qbps.txt
txt: txt/cord-283804-dje7qbps.txt
summary:
  The B e a u d e t t e strain is serologically similar to t h e 104 to 10 a TCDs0 of virus was i n o c u l a t e d b y t h e allantoic route into 10 d a y old e m b r y o n a t e d chicken eggs which were t h e n i n c u b a t


id: cord-283178-4wefykbi
author: Deng, Xiaoyu
date: 2018-04-19
extension: .txt
mime: text/plain
words: 2616
sentence: 106
flesch: 50
cache: cache/cord-283178-4wefykbi.txt
txt: txt/cord-283178-4wefykbi.txt
title:
  A multiplex PCR method for the simultaneous detection of three viruses associated with canine viral enteric infections

summary:
  Several detection methods for these three viruses exist [6, 12, 13] , but no single method can detect the presence of all three viruses together. The specificity of the mPCR results showed no amplification of canine distemper virus (CDV), canine parainfluenza virus (CPIV), or pseudorabies virus (PRV), indicating that the method had good specificity.


id: cord-294467-kq5wmavt
author: Kasai, H.
date: 2014-04-08
extension: .txt
mime: text/plain
words: 1953
sentence: 97
flesch: 56
cache: cache/cord-294467-kq5wmavt.txt
txt: txt/cord-294467-kq5wmavt.txt
title:
  Characterization of haemagglutinin-esterase protein (HE) of murine corona virus DVIM by monoclonal antibodies

summary:
  Cytopathic effect (fusion from within) is shown by asteriks virus cell fusion activity, because syncytia were observed by 24 h p.i. These results indicate that the antigenic epitopes of this glycoprotein can be classified into at least two groups and that the functional sites of HA and AE activities are similar but not identical.


id: cord-295308-ruwxm4fd
author: Chen, S.-P.
date: 2008-04-30
extension: .txt
mime: text/plain
words: 1501
sentence: 58
flesch: 41
cache: cache/cord-295308-ruwxm4fd.txt
txt: txt/cord-295308-ruwxm4fd.txt
title:
  Identification of a recombinant dengue virus type 1 with 3 recombination regions in natural populations in Guangdong province, China

summary:
  As seen in Fig. 2 , the left panels represent non-recombination regions and the right ones, recombination regions. We compared these phylogenetic trees and found that the topology of the phylogenetic trees in the left panels (nonrecombination regions) was very different from that of the trees in the right panels (recombination regions).


id: cord-291530-ffex7dw9
author: Escutenaire, S.
title: Characterization of divergent and atypical canine coronaviruses from Sweden
date: 2007-05-29
extension: .txt
mime: text/plain
words: 2330
sentence: 100
flesch: 52
cache: cache/cord-291530-ffex7dw9.txt
txt: txt/cord-291530-ffex7dw9.txt
summary:
  In the tree based on M gene sequences, the viruses from Sweden segregated into two distinct subgroups among the CCVs type II (Fig. 2a) . A clustering of RNA recombination sites adjacent to a hypervariable region of the peplomer gene of murine coronavirus SYBR Green real-time reverse transcription-polymerase chain reaction assay for the generic detection of coronaviruses One-tube fluorogenic reverse transcriptionpolymerase chain reaction for the quantitation of feline coronaviruses Feline coronavirus type II strains 79-1683 and 79-1146 originate from a double recombination between feline coronavirus type I and canine coronavirus Comparison of the amino acid sequence and phylogenetic analysis of the peplomer, integral membrane and nucleocapsid proteins of feline, canine and porcine coronaviruses Identification of canine coronavirus strains from feces by S gene nested PCR and molecular characterization of a new Australian isolate Genetic evolution of canine coronavirus and recent advances in prophylaxis Two genotypes of canine coronavirus simultaneously detected in the fecal samples of dogs with diarrhea Cloning and expression of two fragments of the S gene of canine coronavirus type I Genetic diversity of a canine coronavirus detected in pups with diarrhoea in Italy Identification of coronaviruses in dogs that segregate separately from the canine coronavirus genotype Molecular characterization of a virulent canine coronavirus BGF strain A comparison of the genomes of FECVs and FIPVs and what they tell us about the relationships between feline coronaviruses and their evolution Evidence of natural recombination within the S1 gene of infectious bronchitis virus The S gene of canine coronavirus, strain UCD-1, is more closely related to the S gene of transmissible gastroenteritis virus than to that of feline infectious peritonitis virus


id: cord-260708-l9w5jhsw
author: Lasecka, Lidia
title: The molecular biology of nairoviruses, an emerging group of tick-borne arboviruses
date: 2013-12-11
extension: .txt
mime: text/plain
words: 10711
sentence: 338
flesch: 38
cache: cache/cord-260708-l9w5jhsw.txt
txt: txt/cord-260708-l9w5jhsw.txt
summary:
  This genus includes a number of human and livestock pathogens, as well as a collection of other viruses about which little is known, not even the host in which they naturally circulate. Region 1, based on sequence similarity with other viruses, appears to be responsible for capsnatching endonuclease activity [52, 136, 189] ; however, this needs to be confirmed experimentally.


id: cord-288948-89cdfhi0
author: Campalto, M.
title: Divergent minute virus of canines strains identified in illegally imported puppies in Italy
date: 2020-10-08
extension: .txt
mime: text/plain
words: 1926
sentence: 69
flesch: 50
cache: cache/cord-288948-89cdfhi0.txt
txt: txt/cord-288948-89cdfhi0.txt
summary:
  This study reports the characterization of four divergent MVC strains detected between 2012 and 2018, three of which were from dogs illegally imported into Italy, most probably from Eastern Europe, that cluster together phylogenetically but share low genetic similarity with the fourth MVC from an autochthonous dog and other available MVC sequences. The VP1 protein is critical for MVC infection, while VP2 mediates receptor recognition and nuclear translocation [3] .


id: cord-291718-cz1bi0ym
author: Yu, Liping
title: The papain-like protease of avian infectious bronchitis virus has deubiquitinating activity
date: 2017-03-18
extension: .txt
mime: text/plain
words: 3488
sentence: 140
flesch: 49
cache: cache/cord-291718-cz1bi0ym.txt
txt: txt/cord-291718-cz1bi0ym.txt
summary:
  Further investigations are necessary to determine if IBV PLP DUB activity inhibits the host antiviral response. Further experiments indicated that the proteinase PLP-TM plays an important role in IBV DUB activity and can process both K48-and K63-linked polyubiquitin chains.


id: cord-271884-86yl9ren
author: Traavik, T.
title: Development of a modified immunoelectroosmophoresis method for Uukuniemi and Runde virus serology
date: 1977
extension: .txt
mime: text/plain
words: 3121
sentence: 170
flesch: 51
cache: cache/cord-271884-86yl9ren.txt
txt: txt/cord-271884-86yl9ren.txt
summary:
  E O P for antibody detection might prove valuable also with other viruses. Rabbits received 3 injections of virus grown on BI-IK cells, concentrated 100 times by PEG/NaC1 and sonieated.


id: cord-264392-he1vekrt
author: Lambeth, L. S.
title: Complete genome sequence of Nariva virus, a rodent paramyxovirus
date: 2008-12-23
extension: .txt
mime: text/plain
words: 4373
sentence: 172
flesch: 48
cache: cache/cord-264392-he1vekrt.txt
txt: txt/cord-264392-he1vekrt.txt
summary:
  This was then followed by PCR to fill in the ''gaps'' using specific primers designed from NarPV Nariva virus genome 201 sequences obtained from the cDNA subtraction or degenerate primers designed using highly conserved consensus sequences of known paramyxoviruses in the subfamily Paramyxovirinae. c Alignment of the V-specific protein sequences NarPV F protein, SGRNK, is dibasic and does not conform to the consensus sequence motif for cleavage by furin, R-X-K/R-R


id: cord-296167-np0b9a7o
author: Mardani, Karim
title: Naturally occurring recombination between distant strains of infectious bronchitis virus
date: 2010-06-24
extension: .txt
mime: text/plain
words: 2965
sentence: 104
flesch: 44
cache: cache/cord-296167-np0b9a7o.txt
txt: txt/cord-296167-np0b9a7o.txt
summary:
  Analysis of the S gene sequences of Australian IBV strains showed that, among classical strains, they differed by 3-12.5% and, among novel strains, by 3.2-16.4%. Evolutionary relationships between Australian IBV genes were inferred using the neighbour-joining method [24] .


id: cord-308950-bl83r4v3
author: Miguel, B.
title: The role of feline aminopeptidase N as a receptor for infectious bronchitis virus : Brief Review
date: 2002
extension: .txt
mime: text/plain
words: 2550
sentence: 92
flesch: 44
cache: cache/cord-308950-bl83r4v3.txt
txt: txt/cord-308950-bl83r4v3.txt
summary:
  To determine if IBV could replicate in the FEK cells, cell cultures were infected with Ark/IBV and the supernatants from infected cells were collected at 1, 2, 3 and 10 d PI. The objectives of this study were to: (1) determine if feline cells were permissive to Arkansas 99 (Ark 99) serotype of IBV, (2) evaluate if the IBV can replicate in feline cells, and (3) determine the contribution of APN to permissiveness of feline cells.


id: cord-290695-ubrqy2zf
author: Payne, H. R.
title: Analysis of cell fusion induced by bovine coronavirus infection
date: 1988
extension: .txt
mime: text/plain
words: 2086
sentence: 87
flesch: 45
cache: cache/cord-290695-ubrqy2zf.txt
txt: txt/cord-290695-ubrqy2zf.txt
summary:
  key: cord-290695-ubrqy2zf authors: Payne, H. R.; Storz, J. title: Analysis of cell fusion induced by bovine coronavirus infection date: 1988 journal: Arch Virol DOI: 10.1007/bf01319806 sha: doc_id: 290695 cord_uid: ubrqy2zf Polykaryon formation in bovine fetal spleen (BFS) cells infected with bovine coronavirus L9 occurred only in media supplemented with trypsin. Cell fusion and polykaryon formation in cultures infected with bovine coronavirus (BCV) occur late in the virus replication cycle.


id: cord-299345-2i48ld8d
author: Nefedeva, Mariia
title: Molecular characteristics of a novel recombinant of porcine epidemic diarrhea virus
date: 2019-02-06
extension: .txt
mime: text/plain
words: 1536
sentence: 70
flesch: 40
cache: cache/cord-299345-2i48ld8d.txt
txt: txt/cord-299345-2i48ld8d.txt
summary:
  KC109141.1_PEDV_isolate_JS2008 JQ023162.1_PEDV_strain_aƩenuated_DR13_2003 JQ023161.1_PEDV_strain_virulent_DR13_1999 MF577027.1_PEDV_strain_PEDV/Belgorod/dom KX499468.1_TGEV_strain_TGEV_AHHF_2015 DQ201447.1_TGEV_strain_TS_2006 New variants of porcine epidemic diarrhea virus, China Emergence of Porcine epidemic diarrhea virus in the United States: clinical signs, lesions, and viral genomic sequences Molecular characterization and phylogenetic analysis of membrane protein genes of porcine epidemic diarrhea virus isolates in China Genomic and epidemiological characteristics provide new insights into the phylogeographical and spatiotemporal spread of porcine epidemic diarrhea virus in Asia Sequence analysis of the partial spike glycoprotein gene of porcine epidemic diarrhea viruses isolated in Korea Detection of porcine epidemic diarrhea virus using polymerase chain reaction and comparison of the nucleocapsid protein genes among strains of the virus Porcine epidemic diarrhea virus infection: Etiology, epidemiology, pathogenesis and immunoprophylaxis Cell culture isolation and sequence analysis of genetically diverse US porcine epidemic diarrhea virus strains including a novel strain with a large deletion in the spike gene New variant of porcine epidemic diarrhea virus Comparison of porcine epidemic diarrhea viruses from Germany and the United States Genomic and evolutionary inferences between American and global strains of porcine epidemic diarrhea virus Distinct characteristics and complex evolution of PEDV strains Complete genome sequence of a porcine epidemic diarrhea virus RDP4: Detection and analysis of recombination patterns in virus genomes Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination SDT: a virus classification tool based on pairwise sequence alignment and identity calculation MUSCLE: multiple sequence alignment with high accuracy and high throughput Isolation and identification of porcine epidemic diarrhea virus in pigs under the outbreak at a large farm Biological characteristics of an epizootic isolate BS-08 of porcine epidemic diarrhea virus Porcine epidemic diarrhea virus and discovery of a recombinant swine enteric coronavirus New chimeric porcine coronavirus in swine feces Characterization of a novel chimeric swine enteric coronavirus from diseased pigs in Central Eastern Europe in 2016 Genome sequencing and analysis of a novel recombinant porcine epidemic diarrhea virus strain from Henan, China Acknowledgements We thank Olga Strizhakova for providing PEDV/ Belgorod/dom/2008.


id: cord-294947-g4ntyddb
author: Zhu, Yu
date: 2016-06-10
extension: .txt
mime: text/plain
words: 2856
sentence: 119
flesch: 48
cache: cache/cord-294947-g4ntyddb.txt
txt: txt/cord-294947-g4ntyddb.txt
title:
  Establishment of a nanoparticle-assisted RT-PCR assay to distinguish field strains and attenuated strains of porcine epidemic diarrhea virus

summary:
  Industry, veterinarians trying to contain PED virus, new to the US Isolation and characterization of porcine epidemic diarrhea viruses associated with the 2013 disease outbreak among swine in the US Receptor usage and cell entry of porcine epidemic diarrhea coronavirus Binding characterization of determinants in porcine aminopeptidase N, the cellular receptor for transmissible gastroenteritis virus Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release Characterisation of a recent virulent transmissible gastroenteritis virus from Britain with a deleted ORF 3a Differentiation of a Vero cell adapted porcine epidemic diarrhea virus from Korean field strains by restriction fragment length polymorphism analysis of ORF 3 PEDV ORF3 encodes an ion channel protein and regulates virus production Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field isolates in Korea Isolation and serial propagation of porcine epidemic diarrhea virus in cell cultures and partial characterization of the isolate Rapid and sensitive detection of porcine epidemic diarrhea virus by reverse transcription loop-mediated isothermal amplification combined with a vertical flow visualization strip Evaluation of two real-time polymerase chain reaction assays for Porcine epidemic diarrhea virus (PEDV) to assess PEDV transmission in growing pigs Effect of temperature on the detection of porcine epidemic diarrhea virus and transmissible gastroenteritis virus in fecal samples by reverse transcription-polymerase chain reaction NanoPCR observation: different levels of DNA replication fidelity in nanoparticle-enhanced polymerase chain reactions Porcine epidemic diarrhea virus infection: Etiology, epidemiology, pathogenesis and immunoprophylaxis Molecular epidemiology of porcine epidemic diarrhea virus in China Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field strains in south China A nanoparticleassisted PCR assay to improve the sensitivity for rapid detection and differentiation of wild-type pseudorabies virus and genedeleted vaccine strains A new nanoPCR molecular assay for detection of porcine bocavirus Development of a nanoparticle-assisted PCR assay for detection of porcine epidemic diarrhea virus Acknowledgements Porcine epidemic diarrhea virus (PEDV) is a highly pathogenic and lethal virus.


id: cord-270473-5tok4mqk
author: Nanda, S. K.
date: 2003-09-19
extension: .txt
mime: text/plain
words: 7111
sentence: 259
flesch: 44
cache: cache/cord-270473-5tok4mqk.txt
txt: txt/cord-270473-5tok4mqk.txt
title:
  Mitochondrial HSP70, HSP40, and HSP60 bind to the 3′ untranslated region of the Murine hepatitis virus genome

summary:
  The finding that antibodies to HSP40 and HSP60 only supershifted a relatively small portion of RNA-protein complex 1 suggests that for these two chaperones, only a small fraction of these molecules participated in the formation of MHV RNA-protein complexes. MHV RNA-protein complexes (4, 6, 8) or with primers for the abundant mRNA for GAPDH (5, 7, 9) .


id: cord-006106-u5npu6ng
author: Attoui, H.
date: 2002
extension: .txt
mime: text/plain
words: 7025
sentence: 266
flesch: 45
cache: cache/cord-006106-u5npu6ng.txt
txt: txt/cord-006106-u5npu6ng.txt
title:
  Genus Coltivirus (family Reoviridae): genomic and morphologic characterization of Old World and New World viruses

summary:
  According to the standard designation of segments in which numbers are assigned in a decreasing order of size (S1 being the largest and S12 the smallest), there is one change in homologous EYA virus and CTF virus segments: segment 6 of EYA virus strain Fr578 is homologous to segment 7 of CTF virus strain Florio and vice versa. PCR primers were designed from the sequences of the first, sixth, seventh and twelfth genome segments of CTF virus and EYA virus (primer sequences are shown in Table 1 ).


id: cord-312338-r6jqmes3
author: Althani, Asma
title: Characterisation of winter respiratory viral infections in patients with asthma and COPD in Qatar
date: 2012-12-14
extension: .txt
mime: text/plain
words: 2423
sentence: 120
flesch: 50
cache: cache/cord-312338-r6jqmes3.txt
txt: txt/cord-312338-r6jqmes3.txt
summary:
  Our study is the first in Qatar to analyse the clinical aetiology of respiratory tract viral infections in adult patients from all age groups with asthma or COPD. In the last several years, respiratory virus infections have been identified in [50 % of wheezing episodes in adults [1, 3, 9] .


id: cord-010900-2ie1v1wy
author: Ramírez-Salinas, G. Lizbeth
date: 2020-02-14
extension: .txt
mime: text/plain
words: 7107
sentence: 301
flesch: 45
cache: cache/cord-010900-2ie1v1wy.txt
txt: txt/cord-010900-2ie1v1wy.txt
title:
  Bioinformatics design and experimental validation of influenza A virus multi-epitopes that induce neutralizing antibodies

summary:
  Carma: a molecular dynamics analysis program Neutrophils extracellular traps damage Naegleria fowleri trophozoites opsonized with human IgG Influenza viruses: an introduction Simplified plaque reduction neutralization assay for dengue viruses by semimicro methods in BHK-21 cells: comparison of the BHK suspension test with standard plaque reduction neutralization Differences in antibody responses of individuals with natural infection and those vaccinated against pandemic H1N1 2009 influenza Immuno-fluorescence assay of leptospiral surface-exposed proteins Neutralization of virus infectivity by antibodies: old problems in new perspectives Structural and thermodynamic approach to peptide immunogenicity Virus-specific T cells as correlate of (cross-)protective immunity against influenza The effector T cell response to influenza infection Antiviral CD8+ T cell effector activities in situ are regulated by target cell type B cell responses to influenza infection and vaccination T cell activation Exploring the immunome: a brave new world for human vaccine development Bronchus-and nasal-associated lymphoid tissues Mechanism and regulation of class switch recombination Protection against influenza virus infection in polymeric Ig receptor knockout mice immunized intranasally with adjuvant-combined vaccines A nasally administered trivalent inactivated influenza vaccine is well tolerated, stimulates both mucosal and systemic immunity, and potentially protects against influenza illness Mucosal IgA responses in influenza virus infections; thoughts for vaccine design How a single amino acid change may alter the immunological information of a peptide Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells Immunity to pre-1950 H1N1 influenza viruses confers cross-protection against the pandemic swineorigin 2009 A (H1N1) influenza virus Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections Preexisting human antibodies neutralize recently emerged H7N9 influenza strains Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population Assessment of seasonal influenza Currently, the primary goal is to develop vaccines that protect by eliciting antibody responses against multiple subtypes and strains of influenza viruses [8] [9] [10] .


id: cord-307098-oq7zrnuv
author: Taguchi, F.
title: Difference in Bgp-independent fusion activity among mouse hepatitis viruses
date: 2014-05-20
extension: .txt
mime: text/plain
words: 2684
sentence: 116
flesch: 51
cache: cache/cord-307098-oq7zrnuv.txt
txt: txt/cord-307098-oq7zrnuv.txt
summary:
  Under a phase contrast microscopy, JHMV (cl-2, sp-4) induced the Bgp-independent syncytia on BHK cells similar to those observed on DBT cells, while such syncytia were not seen with the infection of other MHV strains (MHV-1, MHV-3, MHV-A59, MHV-S, srr7, srr11 and srr18). This size difference observed on BHK cells between cl-2 and sp-4 was in good agreement with the size difference in anti-S1 MAbs and anti-mouse IgG labelled with FITC for immunofluorescence plaque produced on DBT cells [30] .


id: cord-285892-tp6mlqtw
author: Li, Yingli
title: Isolation of two Chinese bovine enteroviruses and sequence analysis of their complete genomes
date: 2012-08-01
extension: .txt
mime: text/plain
words: 2959
sentence: 109
flesch: 46
cache: cache/cord-285892-tp6mlqtw.txt
txt: txt/cord-285892-tp6mlqtw.txt
summary:
  In this study, for the China BEV isolates BHM26 and BJ50, sequence analysis based on the 5 0 UTR and 3 0 UTR and P1, P2 and P3 subgenomic regions yielded some incongruent results, suggesting that there were intergenotypic recombination events occurring during evolution of the BHM26 and BJ50 isolates. Oligonucleotide primers (Table 1 ) used in this study were designed according to the consensus sequences of the 12 fully sequenced BEV RNA genomes available from the GenBank database.


id: cord-302063-ct5rvqtd
author: Mohamed, Fakry F.
title: Molecular detection of enteric viruses from diarrheic calves in Egypt
date: 2016-09-29
extension: .txt
mime: text/plain
words: 3204
sentence: 151
flesch: 53
cache: cache/cord-302063-ct5rvqtd.txt
txt: txt/cord-302063-ct5rvqtd.txt
summary:
  Bovine rotavirus and bovine coronavirus (BRV and BCV) are the leading causes of viral diarrhea [2] , although bovine viral diarrhea virus (BVDV), bovine norovirus (BNoV), bovine astrovirus (BAstV) and bovine torovirus (BToV) have also been implicated. RNA was extracted and tested by reverse transcription polymerase chain reaction (RT-PCR) for the presence of rotavirus, norovirus, astrovirus, torovirus, coronavirus and bovine viral diarrhea virus.


id: cord-324377-br2uorg8
author: Zhou, Pei
title: Antiviral effect of lithium chloride on infection of cells by canine parvovirus
date: 2015-08-28
extension: .txt
mime: text/plain
words: 2951
sentence: 124
flesch: 53
cache: cache/cord-324377-br2uorg8.txt
txt: txt/cord-324377-br2uorg8.txt
summary:
  Molecular targets for lithium's actions Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons Cellular uptake and infection by canine parvovirus involves rapid dynamin-regulated clathrinmediated endocytosis, followed by slower intracellular trafficking Natural variation of canine parvovirus Canine host range and a specific epitope map along with variant sequences in the capsid protein gene of canine parvovirus and related feline, mink, and raccoon parvoviruses The global spread and replacement of canine parvovirus strains Mapping specific functions in the capsid structure of canine parvovirus and feline panleukopenia virus using infectious plasmid clones A simple method of estimating fifty per cent endpoints Action mechanisms of lithium chloride on cell infection by transmissible gastroenteritis coronavirus Characteristics and taxonomy of Parvoviridae The effect of lithium chloride on the replication of Herpes simplex virus Antiviral effect of diammonium glycyrrhizinate and lithium chloride on cell infection by pseudorabies herpesvirus The three-dimensional structure of canine parvovirus and its functional implications Intracellular route of canine parvovirus entry Lithium chloride restores host protein synthesis in herpes simplex virus-infected endothelial cells F81 cells (1 9 10 4 cells) were cultured in 24-well plates, and nontoxic concentrations (0, 10, 20, 40 and 60 mM) of LiCl mixed with CPV(1 9 10 -2 TCID 50 /cell) were added to the cells, which were then incubated at 37°C for 72 h. As a control, cells infected with the same dose of CPV were not treated with LiCl.


id: cord-316797-sf2lu45f
author: Hirano, N.
title: Replication of rat coronavirus in a rat cell line, LBC
date: 1985
extension: .txt
mime: text/plain
words: 897
sentence: 39
flesch: 57
cache: cache/cord-316797-sf2lu45f.txt
txt: txt/cord-316797-sf2lu45f.txt
summary:
  key: cord-316797-sf2lu45f authors: Hirano, N.; Ono, K.; Sada, Y.; Inoue, A.; Murakami, T.; Takamaru, H. title: Replication of rat coronavirus in a rat cell line, LBC date: 1985 journal: Arch Virol DOI: 10.1007/bf01314238 sha: doc_id: 316797 cord_uid: sf2lu45f Rat coronavirus readily propagated and induced marked cytopathic effect in a rat cell line, LBC cell culture, which provided a sensitive, practical assay system for viral infectivity and neutralizing antibody, and a satisfactory source of the virus. The culture fluid sampled at ¢8 hours p.i. was assayed for infectivity by inoculating into LBC cells prepared in 13 × 100 mm test tubes, showing an infectivity titer of i07.5 50 per cent tissue culture infective doses (TCIDs0)/0.2 ml.


id: cord-310669-6hwq5jfv
author: Erles, K.
date: 2005-04-21
extension: .txt
mime: text/plain
words: 4107
sentence: 165
flesch: 55
cache: cache/cord-310669-6hwq5jfv.txt
txt: txt/cord-310669-6hwq5jfv.txt
title:
  Investigation into the causes of canine infectious respiratory disease: antibody responses to canine respiratory coronavirus and canine herpesvirus in two kennelled dog populations

summary:
  The overall prevalence of CHV positive dogs over the study period was 7.9 percent and in total only four dogs seroconverted to CHV (Fig. 2) . Overall the percentage of CHV antibody positive dogs was 16.7 percent (9 out of 54) on the day of entry into Kennel A. Dogs joining the kennel from June 2001 to September 2001 were more likely to be positive than those joining during the following months (Table 1) .


id: cord-316153-wet0go35
author: Jia, W.
date: 1995
extension: .txt
mime: text/plain
words: 3937
sentence: 159
flesch: 53
cache: cache/cord-316153-wet0go35.txt
txt: txt/cord-316153-wet0go35.txt
title:
  A novel variant of avian infectious bronchitis virus resulting from recombination among three different strains

summary:
  Phagemids containing IBV genes were prepared by in vivo excision in Escherichia coli (E. coli) using a protocol furnished by Stratagene (La Jolla, CA). In both the indirect and antigen-capture ELISA, the Ark-specific and Mass-specific MAbs reacted with both the whole virions and the purified S1 protein of CU T2 strain (Table 1) .


id: cord-309145-6aqc074e
author: Ito, Y.
date: 1994
extension: .txt
mime: text/plain
words: 4394
sentence: 159
flesch: 29
cache: cache/cord-309145-6aqc074e.txt
txt: txt/cord-309145-6aqc074e.txt
title:
  Induction of interferon by virus glycoprotein(s) in lymphoid cells through interaction with the cellular receptors via lectin-like action: An alternative interferon induction mechanism

summary:
  Therefore, an interaction between viral virus glycoproteins and virus receptors of host cells at the cell surface can induce or enhance cellular macromolecular syntheses. The glycoprotein isolated from vesicular stomatitis virus is mitogenic for mouse B lymphocytes Mitogenic activity of Sindbis virus and it's isolated gtycoproteins The major human rhinovirus receptor is ICAM-t Human (HLA-A and HLA-B) and murine (H-2K and H-2D) histocompatibility antigens are cell surface receptors for semliki forest virus Adsorption of influenza hemagglutinin and virus by red blood cells Mouse Ia antigens are receptors for lactate dehydrogenase virus Interferon-like substance of ovine trophoblast protein secreted by embryonic trophectoderm Virus interference: I The interferon Production of interferon-like substance by mouse spleen ceils through contact with BHK cells persistently infected with HVJ Interferon induction in mice by BHK cells persistently infected with HVJ Active component of HVJ (Sendal virus) for interferon induction in mice Mechanism of interferon induction in mouse spleen cells stimulated with HVJ Component(s) of Sendai virus that can induce interferon in mouse spleen cells The effects of cytochalasin and colchicine on interferon production Suppression of interferon production in mouse spleen cells by cytochalasin D Interferonproducing capacity of germfree mice Interferon induction in mouse spleen cells by mitogenic and nonmitogenic lectins Interferon production in mouse spleen cells and mouse fibroblasts (L cells) stimulated by various strains of Newcastle disease virus HN proteins of human parainfluenza type 4A virus expressed in cell lines transfected with a cloned cDNA have an ability to induce interferon in mouse spleen cells Transport of cationic amino acids by the mouse ecotropic retrovirus receptor In vitro mitogenic stimulation of murine spleen cells by herpes simplex virus Sendai virus glycoproteins are T cell-dependent B cell mitogens T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV Viral glycoproteins and interferon induction 197 A cytokine network in human diploid fibroblasts: Interaction of 13-interferons, tumor necrosis factor, platelet-derived growth factor, and interleuken-1 The poliovirus receptor protein is produced both as membrane-bound and secreted forms Lymphocyte activation by HIV-1 envelope glycoprotein Is the acetylcholine receptor a rabies virus receptor?


id: cord-289926-y1rjgbui
author: Veretnik, S.
title: RNA binding domain of HDV antigen is homologous to the HMG box of SRY
date: 2014-05-18
extension: .txt
mime: text/plain
words: 6687
sentence: 253
flesch: 48
cache: cache/cord-289926-y1rjgbui.txt
txt: txt/cord-289926-y1rjgbui.txt
summary:
  Sequence alignments were performed using programs from the GCG Wisconsin Package version 8. Monte Carlo evaluation of sequence alignments was done using the GAP program with the option '-RANDOM=10000'.


id: cord-298883-uiwg482s
author: Truong, C.
date: 2001
extension: .txt
mime: text/plain
words: 4180
sentence: 163
flesch: 45
cache: cache/cord-298883-uiwg482s.txt
txt: txt/cord-298883-uiwg482s.txt
title:
  Identification of an immunorelevant ORF2 epitope from porcine circovirus type 2 as a serological marker for experimental and natural infection

summary:
  Here, we describe the characterization of an Orf2 peptide as an immunorelevant PCV2 specific linear B-cell epitope by ELISA, using sera from pigs experimentally inoculated with a PCV2 isolate, and its potential use as a serological marker to detect PCV2 antibodies following natural infection in swine herds. PCV2 antibodies were previously detected in this serum by IPMA.


id: cord-330825-apfcql4m
author: Paraguison-Alili, Rubigilda
title: Phylogenetic tracking of current porcine epidemic diarrhea virus (PEDV) strains in the Philippines
date: 2016-06-28
extension: .txt
mime: text/plain
words: 2179
sentence: 85
flesch: 47
cache: cache/cord-330825-apfcql4m.txt
txt: txt/cord-330825-apfcql4m.txt
summary:
  Since the receptor-binding sites and majority of the neutralization epitopes are located in the S1 portion, this region has been subjected to sequencing and molecular analysis to determine the genetic relatedness of different PEDV viruses This is the first report of PEDV S1 gene sequences from the provincial PEDV hotspots of the Philippines, which include Batangas, Pampanga, Tarlac and Agusan.


id: cord-312787-j7ye7ed5
author: Loemba, H. D.
date: 1996
extension: .txt
mime: text/plain
words: 3424
sentence: 119
flesch: 36
cache: cache/cord-312787-j7ye7ed5.txt
txt: txt/cord-312787-j7ye7ed5.txt
title:
  Kinetics of humoral immune response to the major structural proteins of the porcine reproductive and respiratory syndrome virus

summary:
  Comparison of porcine alveolar macrophages and CL 2621 for the detection of porcine reproductive and respiratory syndrome (PRRS) virus and anti-PRRS antibody Characterization of swine infertility and respiratory syndrome (SIRS) virus (isolate ATCC VR-2332) Persistence of porcine reproductive and respiratory syndrome virus infection in a swine operation Antibody-dependent enhancement of SIRS virus replication Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction Molecular characterization of porcine reproductive and respiratory syndrome virus, a member of the arterivirus group Structural proteins of equine arteritis virus Porcine reproductive and respiratory syndrome Enhanced replication of porcine reproductive and respiratory syndrome (PRRS) virus in a homogeneous subpopulation of MA-104 cell line Antigenic comparison of Canadian and U.S. isolates of porcine reproductive and respiratory syndrome virus using monoclonal antibodies to the nucleocapsid protein Porcine reproductive and respiratory syndrome virus: morphological, biochemical and serological characteristics of Quebec isolates associated to acute and chronic outbreaks of PRRS Detection of porcine reproductive and respiratory syndrome virus and efficient differentiation between Canadian and European strains by reverse transcription and PCR amplification Molecular analysis of the ORFs 3 to 7 genes of porcine reproductive and respiratory syndrome virus, Quebec strain IAF-exp91 Kinetics of humoral immune response to structural proteins of PRRSV 761 Diagnosis of porcine reproductive and respiratory syndrome Lelystad virus, the causative agent of porcine epidemic abortion and respiratory syndrome (PEARS), is related to LDV and EAV Characterization of proteins encoded by ORFs 2 to 7 of Lelystad virus Differentiation of US and European isolates of porcine reproductive and respiratory syndrome virus by monoclonal antibodies Serum immune responses to the proteins of porcine reproductive and respiratory syndrome (PRRS) virus Antibody production and blastogenic response in pigs experimentally infected with PRRS virus Mystery swine disease in The Netherlands: the isolation of Lelystad virus Morrison RB (t992) An indirect fluorescent antibody test for the detection of antibody to swine infertility and respiratory syndrome virus in swine sera A modified serum neutralization test for the detection of antibody to porcine reproductive and respiratory syndrome virus in swine sera Persistent and contact infection in nursery pigs experimentally infected with porcine reproductive and respiratory syndrome virus Characterization of the humoral immune response to porcine reproductive and respiratory syndrome (PRRS) virus infection We thank Louise Wilson, Micheline Ch6nard, and Nicole Sawyer tbr their technical assistance. Briefly, replicas of viral proteins, separated by SDS-PAGE and electrophoretically transferred onto nitrocellulose membranes, were incubated for 1 h at 37 °C in the presence of 1:50 dilution of the tested porcine sera.


id: cord-321471-gev5xq3a
author: Zhu, Liqian
title: Control of the PI3K/Akt pathway by porcine reproductive and respiratory syndrome virus
date: 2013-02-05
extension: .txt
mime: text/plain
words: 3778
sentence: 157
flesch: 47
cache: cache/cord-321471-gev5xq3a.txt
txt: txt/cord-321471-gev5xq3a.txt
summary:
  The objective of this study was to address how the PI3K/Akt pathway is modulated in infection of MARC-145 cells and PAMs with highly pathogenic PRRSV. Akt pathway was significantly enhanced by the HuN4 virus at both the early and late stage of infection of MARC-145 cells, while a distinct pattern was adopted during infection of PAMs in which the phosphorylation of Akt occurred exclusively in the early stage, as early as 5 min p.i., and then returned to the basal level at 45 min p.i.


id: cord-292286-ygomb3oi
author: Zakaryan, Hovakim
title: Flavonoids: promising natural compounds against viral infections
date: 2017-05-25
extension: .txt
mime: text/plain
words: 6103
sentence: 241
flesch: 31
cache: cache/cord-292286-ygomb3oi.txt
txt: txt/cord-292286-ygomb3oi.txt
summary:
  Apigenin inhibits enterovirus 71 replication through suppressing viral IRES activity and modulating cellular JNK pathway Antiherpetic activities of flavonoids against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) in vitro Phenolic acids act as signaling molecules in plant-microbe symbioses Identification and evaluation of antihepatitis C virus phytochemicals from Eclipta alba Computational docking study of p7 Ion channel from HCV genotype 3 and genotype 4 and its interaction with natural compounds A flavonoid, luteolin, cripples HIV-1 by abrogation of tat function The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer Evaluation of the antiviral activity of kaempferol and its glycosides against human cytomegalovirus Metabolomics view on gut microbiome modulation by polyphenol-rich foods Baicalin, a metabolite of baicalein with antiviral activity against dengue virus Combined effects of flavonoids and acyclovir against herpesviruses in cell cultures Absorption, excretion and metabolite profiling of methyl-, glucuronyl-, glucosyland sulpho-conjugates of quercetin in human plasma and urine after ingestion of onions Anti-chikungunya activity ofl uteolin and apigenin rich fraction from Cynodon dactylon Neuroprotective effects of chrysin: from chemistry to medicine Differential inhibition of HIV-reverse transcriptase and various DNA and RNA polymerases by somecatechin derivatives Differential inhibitory effects of some catechin derivatives on the activities of human immunodeficiency virus reverse transcriptase and cellular deoxyribonucleic and ribonucleic acid polymerases Inhibition of the infectivity of influenza virus by tea polyphenols Antiviral activity of baicalin against influenza virus H1N1-pdm09 is due to modulation of NS1-mediated cellular innate immune responses Bioavailability is improved by enzymatic modification of the citrus flavonoid hesperidin in humans: a randomized, double-blind, crossover trial silico study on anti-Chikungunya virus activity of hesperetin Anti-Sindbis activity of flavanones hesperetin and naringenin Anti-HIV-1 activity of flavonoid myricetin on HIV-1 infection in a dual-chamber in vitro model Plant derived compounds having activity against P388 and L1210 leukemia cells Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays Genistein inhibits the replication of avian leucosis virus subgroup J in DF-1 cells Apigenin restricts FMDV infection and inhibits viral IRES driven translational activity Anti-inflammatory effect of quercetin-loaded microemulsion in the airways allergic inflammatory model in mice Drugs of natural origin Genistein as antiviral drug against HIV ion channel Absorption and metabolism of polyphenols in the gut and impact on health Kaempferol derivatives as antiviral drugs against the 3a channel protein of coronavirus Comparison of the antiviral activity of flavonoids Antiviral activity of flavonoids against murine norovirus and feline calicivirus Computational approach towards exploring potential anti-Chikungunya activity of selectedflavonoids The flavonoid apigenin inhibits hepatitis C virus replication by decreasing mature microRNA122 levels Differential antiviral and anti-inflammatory mechanisms of the flavonoids biochanin Interestingly, naringin, the glycoside form of naringenin did not have anti-Sindbis virus activity, indicating that the rutinose moiety of this flavanone blocks its antiviral effect.


id: cord-304109-yirs7kjg
author: Mueller, Andreas
title: Polyomaviruses KI and WU in children with respiratory tract infection
date: 2009-09-12
extension: .txt
mime: text/plain
words: 1943
sentence: 95
flesch: 51
cache: cache/cord-304109-yirs7kjg.txt
txt: txt/cord-304109-yirs7kjg.txt
summary:
  WU polyomavirus in children Age-related pattern of KI and WU polyomavirus infection Identification of a third human polyomavirus Cloning of a human parvovirus by molecular screening of respiratory tract samples Identification of the novel KI polyomavirus in the respiratory tract of an Italian patient Presence of the newly discovered human polyomaviruses KI and WU in Australian patients with acute respiratory tract infection A newly reported human polyomavirus, KI virus, is present in the respiratory tract of Australian children Identification of a novel polyomavirus from patients with acute respiratory tract infections WU polyomavirus in children with acute lower respiratory tract infections WU polyomavirus in children with acute lower respiratory tract infections WU polyomavirus infection in children Nasopharyngeal aspirates or bronchoalveolar lavage specimens of 229 children with acute respiratory tract infection were screened for KIPyV and WUPyV using polymerase chain reaction-based methods.


id: cord-302798-q0mbngqy
author: Ge, Junwei
date: 2018-06-14
extension: .txt
mime: text/plain
words: 4347
sentence: 194
flesch: 51
cache: cache/cord-302798-q0mbngqy.txt
txt: txt/cord-302798-q0mbngqy.txt
title:
  Genomic characterization of circoviruses associated with acute gastroenteritis in minks in northeastern China

summary:
  The examination of other MiCV sequences from different regions will help to assess the level of genetic diversity. Other sequences were obtained from GenBank; accession numbers of those sequences are included in the tree to our knowledge of the pathogenic potential of MiCV and its association with mink enteritis if our results were corroborated by further reports.


id: cord-333403-imx3990a
author: Christianson, K. K.
title: Characterization of a temperature sensitive feline infectious peritonitis coronavirus
date: 1989
extension: .txt
mime: text/plain
words: 4010
sentence: 188
flesch: 52
cache: cache/cord-333403-imx3990a.txt
txt: txt/cord-333403-imx3990a.txt
summary:
  Inconsistent protection was found when cats were given a sublethal dose of virulent FIPV and cats vaccinated with an avirulent FIPV were more easily infected than were nonvaccinated cats Feline infectious peritonitis (FIP) is a complex and fatal disease of cats caused by infection with feline infectious peritonitis virus (FIPV).


id: cord-294323-mryiqmsw
author: Kumar, Binod
title: The emerging influenza virus threat: status and new prospects for its therapy and control
date: 2018-01-10
extension: .txt
mime: text/plain
words: 8210
sentence: 298
flesch: 37
cache: cache/cord-294323-mryiqmsw.txt
txt: txt/cord-294323-mryiqmsw.txt
summary:
  A viruses A distinct lineage of influenza A virus from bats The nucleoprotein as a possible major factor in determining host specificity of influenza H3N2 viruses Influenza: the once and future pandemic The origin of the 1918 pandemic influenza virus: a continuing enigma Influenza: the mother of all pandemics Updating the accounts: global mortality of the 1918-1920 Spanish influenza pandemic Characterization of the 1918 influenza virus polymerase genes Is the gene pool of influenza viruses in shorebirds and gulls different from that in wild ducks? Dating the emergence of pandemic influenza viruses Detection and isolation of 2009 pandemic influenza A/H1N1 virus in commercial piggery Role of neuraminidase in lethal synergism between influenza virus and Streptococcus pneumoniae Emerging infections: pandemic influenza Summary report on the Asian influenza epidemic in Japan Public health and medical responses to the 1957-58 influenza pandemic Observations on excess mortality associated with epidemic influenza Understanding original antigenic sin in influenza with a dynamical system Independent variation in nature of hemagglutinin and neuraminidase antigens of influenza virus: distinctiveness of hemagglutinin antigen of Hong Kong-68 virus Origin and progress of the 1968-69 Hong Kong influenza epidemic On the origin of the human influenza virus subtypes H2N2 and H3N2 Influenza pandemics of 1918 and 2009: a comparative account Pandemic swine influenza virus (H1N1): a threatening evolution The persistent legacy of the 1918 influenza virus Pandemic influenza A H1N1 (2009) virus: lessons from the past and implications for the future Pandemic (H1N1) 2009 influenza Pandemic influenza A (H1N1) deaths among children-United States Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California Global mortality estimates for the 2009 Influenza Pandemic from the GLaMOR project: a modeling study Spatial, temporal, and species variation in prevalence of influenza A viruses in wild migratory birds Tissue tropism and pathology of natural influenza virus infection in black-headed gulls (Chroicocephalus ridibundus) Avian Influenza A(H10N7) virus-associated mass deaths among harbor seals Characterization of two influenza A viruses from a pilot whale Influenza virus reservoirs and intermediate hosts: dogs, horses, and new possibilities for influenza virus exposure of humans Equine influenza A(H3N8) virus isolated from Bactrian camel One health, multiple challenges: The inter-species transmission of influenza A virus Preliminary epidemiology of human infections with highly pathogenic avian influenza A(H7N9) virus Human infection with highly pathogenic avian influenza A(H7N9) virus Novel reassortant avian influenza A(H5N6) viruses in humans Highly pathogenic avian influenza virus (H5N8) in domestic poultry and its relationship with migratory birds in South Korea during Avian influenza viruses in mammals Survival of influenza viruses on environmental surfaces Prevalence of gastrointestinal symptoms in patients with influenza, clinical significance, and pathophysiology of human influenza viruses in faecal samples: what do we know Onset and duration of symptoms and timing of disease transmission of 2009 influenza A (H1N1) in an outbreak in Fukuoka Concurrent comparison of epidemiology, clinical presentation and outcome between adult patients suffering from the pandemic influenza A (H1N1) 2009 virus and the seasonal influenza Influenza viruses belong to the family Orthomyxoviridae and are the leading cause of severe respiratory illness across the world.


id: cord-322760-tsxniu3j
author: Sha, Jianping
date: 2016-09-23
extension: .txt
mime: text/plain
words: 4632
sentence: 183
flesch: 53
cache: cache/cord-322760-tsxniu3j.txt
txt: txt/cord-322760-tsxniu3j.txt
title:
  Fatality risks for nosocomial outbreaks of Middle East respiratory syndrome coronavirus in the Middle East and South Korea

summary:
  [17] [18] [19] vs. 9 days [0-24], p = 0.041) and in sporadic MERS cases (12 days vs. 9 days [0-30], p = 0.003). These findings can be attributed to three facts: first, the majority of HCP developed asymptomatic or mild symptoms and moderate symptoms [15] ; second, HCP were confirmed as secondary cases under medical investigation, which led to earlier confirmation and good outcomes [32] ; third, epidemiological analysis showed that HCP were much younger and had fewer co-morbidities compared to total MERS cases [36] .


id: cord-294138-h7sfd1wa
author: McIver, David J.
date: 2020-06-01
extension: .txt
mime: text/plain
words: 2787
sentence: 101
flesch: 49
cache: cache/cord-294138-h7sfd1wa.txt
txt: txt/cord-294138-h7sfd1wa.txt
title:
  Coronavirus surveillance of wildlife in the Lao People’s Democratic Republic detects viral RNA in rodents

summary:
  The 1.4% prevalence of CoV RNA in rodents was much lower than what had been detected in bats in Laos; however, such observations have been made repeatedly, re-emphasizing the role of bats as a primary CoV source [5, [15] Studies in which CoV RNA was more frequently detected in rodents have used intestine or fecal matter for their studies, while we tested oral and rectal swab samples


id: cord-324495-0pee1i3o
author: Kang, Hyeonjeong
date: 2015-06-06
extension: .txt
mime: text/plain
words: 6132
sentence: 231
flesch: 43
cache: cache/cord-324495-0pee1i3o.txt
txt: txt/cord-324495-0pee1i3o.txt
title:
  Sasa quelpaertensis Nakai extract suppresses porcine reproductive and respiratory syndrome virus replication and modulates virus-induced cytokine production

summary:
  Our results demonstrated that SQE treatment suppressed the replication of PRRSV in a dose-dependent manner. PAM-KNU cells were infected with PRRSV along with SQE treatment as described above.


id: cord-306380-msk9p1yy
author: Lee, C.-W.
title: Evidence of genetic diversity generated by recombination among avian coronavirus IBV
date: 2000
extension: .txt
mime: text/plain
words: 2800
sentence: 123
flesch: 54
cache: cache/cord-306380-msk9p1yy.txt
txt: txt/cord-306380-msk9p1yy.txt
summary:
  Sequencing primers to various regions of the gene for DE072 and The relative primer positions were calculated using the ATG start site of Gene 3 as 1 for primers gene 3 and 4, and ATG start site of S1 gene as 1 for primers HVR in S1 D1466 were designed using OLIGO version 4.0 software (National Bioscience, Plymouth, MN, USA) and are available upon request. Gene 4 consisted of the M protein gene with a single ORF and a non-coding region between the 3 end of the M protein gene and gene 5.


id: cord-277847-vgf9lz76
author: Sheppard, M.
date: 2014-04-07
extension: .txt
mime: text/plain
words: 5490
sentence: 230
flesch: 44
cache: cache/cord-277847-vgf9lz76.txt
txt: txt/cord-277847-vgf9lz76.txt
title:
  Fowl adenovirus recombinant expressing VP2 of infectious bursal disease virus induces protective immunity against bursal disease

summary:
  All chickens vaccinated with either Bursavac K or rFAV-10/VP2 had detectable levels of VP2 antibodies and unvaccinated chickens or chickens vaccinated with FAV-10 only, had no detectable VP2 antibodies (not shown). All these birds were negative for VP2 antibody in pre-challenge sera.


id: cord-307378-cx1jz7wf
author: Dadar, Maryam
title: The association between the incidence of COVID-19 and the distance from the virus epicenter in Iran
date: 2020-09-02
extension: .txt
mime: text/plain
words: 2340
sentence: 87
flesch: 43
cache: cache/cord-307378-cx1jz7wf.txt
txt: txt/cord-307378-cx1jz7wf.txt
summary:
  COVID-19 has spread to all 31 Iranian provinces, and the city of Tehran, the densely populated capital with over 13 million people located 150 km northeast of Qom, leads the country in COVID-19 cases ( Table 1) . The incidence rate for each province was calculated as the number of COVID-19 cases diagnosed until 23 March 2020 divided by the population of the province in 2019 and multiplied by 100,000.


id: cord-338641-s006a7m0
author: Black, W. D.
date: 2006-08-24
extension: .txt
mime: text/plain
words: 4049
sentence: 148
flesch: 48
cache: cache/cord-338641-s006a7m0.txt
txt: txt/cord-338641-s006a7m0.txt
title:
  Reverse transcriptase-polymerase chain reaction for the detection equine rhinitis B viruses and cell culture isolation of the virus

summary:
  Other cells used for virus culture, including virus isolation attempts, were Vero cells (passage 130-200), RK13 cells (passage 195-250) and equine foetal kidney (EFK) cells (passage 4). We especially thank Marianne Weiss, University of Berne, P. J. Timoney and W. H. McCollum, University of Kentucky, and Dorothy Holmes and Ed Dubovi, Cornell University, for providing virus isolates and culture history.


id: cord-338916-fqxjzavm
author: Anindita, Paulina Duhita
title: Detection of coronavirus genomes in Moluccan naked-backed fruit bats in Indonesia
date: 2015-02-04
extension: .txt
mime: text/plain
words: 2261
sentence: 87
flesch: 47
cache: cache/cord-338916-fqxjzavm.txt
txt: txt/cord-338916-fqxjzavm.txt
summary:
  What we are watching-five top global infectious disease threats, 2012: a perspective from CDC's Global Disease Detection Operations Center Detection of coronaviruses in bats of various species in Italy Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China The Genome sequence of the SARS-associated coronavirus Middle East respiratory syndrome coronavirus in bats, Saudi Arabia Identification of a novel coronavirus in patients with severe acute respiratory syndrome A novel coronavirus associated with severe acute respiratory syndrome Characterization of a novel coronavirus associated with severe acute respiratory syndrome Coronaviruses as DNA wannabes: a new model for the regulation of RNA virus replication fidelity Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS From SARS coronavirus to novel animal and human coronaviruses Bats and their virome: an important source of emerging viruses capable of infecting humans Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor Bat origins of MERS-CoV supported by bat coronavirus HKU4 usage of human receptor CD26 Genomic and serological detection of bat coronavirus from bats in the Philippines SARS-Coronavirus ancestor's foot-prints in South-East Asian bat colonies and the refuge theory Molecular detection of a novel paramyxovirus in fruit bats from Indonesia Generic detection of coronaviruses and differentiation at the prototype strain level by reverse transcription-PCR and nonfluorescent low-density microarray Evolutionary trees from DNA sequences: a maximum likelihood approach MEGA6: molecular evolutionary genetics analysis version 6.0 Characterization of the envelope glycoprotein of a novel filovirus, lloviu virus Isolation of novel adenovirus from fruit bat Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design Coexistence of different genotypes in the same bat and serological characterization of Rousettus bat coronavirus HKU9 belonging to a novel Betacoronavirus subgroup Detection of novel SARS-like and other coronaviruses in bats from Kenya Differential sensitivity of bat cells to infection by enveloped RNA viruses: coronaviruses, paramyxoviruses, filoviruses, and influenza viruses Virus taxonomy: classification and nomenclature of viruses: Ninth Report of the International Committee on Taxonomy of Viruses Coronavirus genomes in fruit bats in Indonesia 1117 Bats: important reservoir hosts of emerging viruses Bats host major mammalian paramyxoviruses Bat lyssaviruses, northern Vietnam Nipah virus and bats A comparison of bats and rodents as reservoirs of zoonotic viruses: are bats special? Acknowledgements We thank 2 Phylogenetic tree of partial RdRp-helicase using a 2,116-bp nucleotide sequence following removal of primer sequences at the 5 0 and 3 0 end of the partial RdRp-helicase gene obtained from fruit bats samples (IFB2012-8F and IFB2012-17F) and various coronaviruses derived from GenBank.


id: cord-314751-i9rxesrg
author: Oh, Jongsuk
date: 2014-07-10
extension: .txt
mime: text/plain
words: 6085
sentence: 209
flesch: 40
cache: cache/cord-314751-i9rxesrg.txt
txt: txt/cord-314751-i9rxesrg.txt
title:
  Immunogenicity and protective efficacy of recombinant S1 domain of the porcine epidemic diarrhea virus spike protein

summary:
  However, immunizations involving at least one dose of PEDV S1 protein vaccine (groups 2 and 3) were more efficacious than immunization of sows with two doses of PEDV live and killed vaccines (group 1) in reducing the overall degree of diarrhea, in terms of the duration and severity, in the suckling piglets. In contrast, sows immunized with two doses of PEDV live and S1 protein vaccines (group 2) or three doses of S1 protein vaccine (group 3) at 2-week intervals produced relatively lower neutralizing antibody titers of 1:16 to 1:32 compared to those in group 1.


id: cord-334090-66d8c75g
author: Seger, Waleed
title: Genotyping of infectious bronchitis viruses from broiler farms in Iraq during 2014-2015
date: 2016-02-18
extension: .txt
mime: text/plain
words: 3624
sentence: 142
flesch: 49
cache: cache/cord-334090-66d8c75g.txt
txt: txt/cord-334090-66d8c75g.txt
summary:
  Molecular detection of infectious bronchitis virus and it is relation with avian influenza virus (H9) and Mycoplasma gallisepticum from different geographical regions in Iraq Molecular detection of infectious bronchitis and avian metapneumoviruses in Oman backyard poultry Molecular detection of infectious bronchitis and avian metapneumoviruses in Oman backyard poultry Circulation of QX-like infectious bronchitis virus in the Middle East Completion of the sequence of the genome of the coronavirus avian infectious bronchitis virus Detection of the Chinese genotype of infectious bronchitis virus (QX-type) in Iran Development and evaluation of a real-time Taqman RT-PCR assay for the detection of infectious bronchitis virus from infected chickens Coronaviruses in poultry and other birds Variation in the spike protein of the 793/B type of infectious bronchitis virus, in the field and during alternate passage in chickens and embryonated eggs Factors influencing the outcome of infectious bronchitis vaccination and challenge experiments Analysis of S1 gene of avian infectious bronchitis virus isolated in southern China during Genotypes of infectious bronchitis viruses circulating in the Middle East between Turkey coronavirus is more closely related to avian infectious bronchitis virus than to mammalian coronaviruses: a review Phylogenetic study of Iranian infectious bronchitis virus isolates during 2010-2011 using glycoprotein S1 gene Review of infectious bronchitis virus around the world Efficacy of live infectious bronchitis vaccines against a novel European genotype, Italy 02 Development and validation of RT-PCR tests for the detection and S1 genotyping of infectious bronchitis virus and other closely related gammacoronaviruses within clinical samples Presence of IS/1494/06 genotype-related infectious bronchitis virus in breeder and broiler flocks in Turkey Evolutionary and bioinformatics analysis of the spike glycoprotein gene of H120 vaccine strain protectotype of infectious bronchitis virus from India Fenner's veterinary virology Isolation and molecular characterization of Sul/01/09 avian infectious bronchitis virus, indicates the emergence of a new genotype in the Middle East Infectious Bronchitis Virus: a major cause of respiratory disease outbreaks in chickens in Ghana Identification of a novel nephropathogenic infectious bronchitis virus in Israel Complete genome sequences of two Chinese virulent avian coronavirus infectious bronchitis virus variants Detection and molecular characterization of infectious bronchitis virus isolated from recent outbreaks in broiler flocks in Thailand Investigation and molecular characterization of avian infectious bronchitis virus in suspected broiler farms in Slemani Governorate. key: cord-334090-66d8c75g authors: Seger, Waleed; GhalyanchiLangeroudi, Arash; Karimi, Vahid; Madadgar, Omid; Marandi, Mehdi Vasfi; Hashemzadeh, Masoud title: Genotyping of infectious bronchitis viruses from broiler farms in Iraq during 2014-2015 date: 2016-02-18 journal: Arch Virol DOI: 10.1007/s00705-016-2790-2 sha: doc_id: 334090 cord_uid: 66d8c75g Infectious bronchitis virus (IBV) is one of the most critical pathogens in the poultry industry, causing serious economic losses in all countries including Iraq.


id: cord-318731-vlszl0i8
author: Chen, Si
date: 2019-05-31
extension: .txt
mime: text/plain
words: 2224
sentence: 107
flesch: 53
cache: cache/cord-318731-vlszl0i8.txt
txt: txt/cord-318731-vlszl0i8.txt
title:
  Molecular characterization of HLJ-073, a recombinant canine coronavirus strain from China with an ORF3abc deletion

summary:
  Virus taxonomy, 6th report of the International Committee on Taxonomy of Viruses Molecular characterization of feline infectious peritonitis virus strain DF-2 and studies of the role of ORF3abc in viral cell tropism Recovery and characterization of a coronavirus from military dogs with diarrhea Canine coronavirus highly pathogenic for dogs Canine coronavirus highly pathogenic for dogs New enteric viruses in the dog An update on canine coronaviruses: viral evolution and pathobiology Immunity after natural exposure to enteric canine coronavirus does not provide complete protection against infection with the new pantropic CB/05 strain Recombinant canine coronaviruses related to transmissible gastroenteritis virus of Swine are circulating in dogs Quantitation of canine coronavirus RNA in the faeces of dogs by TaqMan RT-PCR A pantropic canine coronavirus genetically related to the prototype isolate CB/05 Molecular characterisation of the virulent canine coronavirus CB/05 strain Molecular characterization and phylogenetic analysis of transmissible gastroenteritis virus HX strain isolated from China Feline and canine coronaviruses: common genetic and pathobiological features Preparation and characterization of mouse polyclonal antibody against conserved region of human FOXO3. Plaque assay for canine coronavirus in CRFK cells The S gene of canine coronavirus, strain UCD-1, is more closely related to the S gene of transmissible gastroenteritis virus than to that of feline infectious peritonitis virus


id: cord-340422-8f5xe4zc
author: Rowland, R. R. R.
date: 2001
extension: .txt
mime: text/plain
words: 4757
sentence: 213
flesch: 45
cache: cache/cord-340422-8f5xe4zc.txt
txt: txt/cord-340422-8f5xe4zc.txt
title:
  Inhibition of porcine reproductive and respiratory syndrome virus by interferon-gamma and recovery of virus replication with 2-aminopurine

summary:
  key: cord-340422-8f5xe4zc authors: Rowland, R. R. R.; Robinson, B.; Stefanick, J.; Kim, T. S.; Guanghua, L.; Lawson, S. R.; Benfield, D. A. title: Inhibition of porcine reproductive and respiratory syndrome virus by interferon-gamma and recovery of virus replication with 2-aminopurine date: 2001 journal: Arch Virol DOI: 10.1007/s007050170161 sha: doc_id: 340422 cord_uid: 8f5xe4zc Porcine reproductive and respiratory syndrome virus (PRRSV) belongs to a group of RNA viruses that establish persistent infections. The effect of IFN-γ on virus replication included reductions in the number of infected cells, virus yield, and RNA content in single cells.


id: cord-333636-h2sg6shp
author: Kochan, G.
date: 2003
extension: .txt
mime: text/plain
words: 6013
sentence: 244
flesch: 47
cache: cache/cord-333636-h2sg6shp.txt
txt: txt/cord-333636-h2sg6shp.txt
title:
  Characterization of the RNA-binding activity of VP3, a major structural protein of Infectious bursal disease virus

summary:
  The affinity of VP3 protein to ssRNA was estimated from three independent experiments using 32 P-labeled virus ssRNA probes. Assuming that the plateau reached represented the complete binding of the RNA, the apparent Kd corresponded to the concentration of VP3 protein required to reach half saturation [21] .


id: cord-307408-6wfx0wey
author: Li, Renfeng
date: 2013-11-30
extension: .txt
mime: text/plain
words: 3230
sentence: 118
flesch: 51
cache: cache/cord-307408-6wfx0wey.txt
txt: txt/cord-307408-6wfx0wey.txt
title:
  Phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field strains in central China based on the ORF3 gene and the main neutralization epitopes

summary:
  In this study, 14 partial S genes from field PEDV strains were amplified by RT-PCR, cloned, sequenced, and analyzed to study their antigenic variation. Sequence comparison with other PEDV reference strains selected from the GenBank database indicated that the ORF3 genes from the sample strains had a high degree of homology to most Chinese strains.


id: cord-306725-0vam15pt
author: Li, Hao
title: First detection and genomic characteristics of bovine torovirus in dairy calves in China
date: 2020-05-09
extension: .txt
mime: text/plain
words: 3021
sentence: 133
flesch: 55
cache: cache/cord-306725-0vam15pt.txt
txt: txt/cord-306725-0vam15pt.txt
summary:
  Nucleotide and deduced amino acid sequences were compared using the MegAlign program of Lasergene software, version 7.1 (DNASTAR, Madison, WI, USA). In this research, we determined the obtained two complete genome sequences of two BToV isolates from the same farm in Sichuan province, increasing the number of BToV genome sequences in the GenBank database to five, thus contributing to a better understanding of the genome structure and genetic evolution of BToV. Phylogenetic analysis indicated that these two BToV isolates had a close genetic relationship to strains from Japan.


id: cord-343131-tu6g977q
author: Cheung, Andrew K.
title: A divergent clade of circular single-stranded DNA viruses from pig feces
date: 2013-04-24
extension: .txt
mime: text/plain
words: 1859
sentence: 77
flesch: 49
cache: cache/cord-343131-tu6g977q.txt
txt: txt/cord-343131-tu6g977q.txt
summary:
  Several sequences encoding amino acid sequences related to Rep of ChiSCV and PoSCV1 were identified. Viral sequences (coronavirus, enterovirus, rotavirus) corresponding to the viruses identified by the Indiana Animal Disease Diagnostic Laboratory (West Lafayette, IN) were detected.


id: cord-343349-ftzjdvfj
author: Bhatt, P. N.
title: Experimental infection of adult axenic rats with Parker's Rat Coronavirus
date: 1977
extension: .txt
mime: text/plain
words: 2131
sentence: 104
flesch: 47
cache: cache/cord-343349-ftzjdvfj.txt
txt: txt/cord-343349-ftzjdvfj.txt
summary:
  Parker and eoworkers previously demonstrated that PRCV caused lethal interstitial pneumonia in experimentally infected suckling rats and they suggested that PRCV could play a role in chronic respiratory disease of adult rats (7) . Mouse Hepatitis Virus (MHV), Viruses of Vertebrates Characterization of the Virus of Sialodacryoadenitis of Rats : A Member of the Coronavirus Group Chromatographic purification of tetramethylrhodamine immune globulin conjugates and their use in the cellular localization of rabbit gammaglobulin peptide chains Pathogenesis of Sialodacryoa.denitis in Gnotobiotic Rats Sialodaeryoadenitis in the Rat (A Light and Electron Miserocopic Study) Keratoeonjunctivitis associated with sialodaeryoadenitis in rats Rat Coronavirus (RCV): A Prevalent., Naturally Occurring Pneumotropie Virus of Rats A simple method of estimating fifty percent and endpoints Supported by PHS Grants RR00700, RR00393 and FR 05358.


id: cord-328381-bfvdhai8
author: Hattermann, K.
title: Susceptibility of different eukaryotic cell lines to SARS-coronavirus
date: 2005-01-13
extension: .txt
mime: text/plain
words: 1835
sentence: 65
flesch: 49
cache: cache/cord-328381-bfvdhai8.txt
txt: txt/cord-328381-bfvdhai8.txt
summary:
  [1] who found ACE2 expression also in cells that were not susceptible for SARS-CoV. Another possibility for lower infection rates in porcine cells may also be that the sequence homology of the human ACE2 strongly deviates from the porcine ACE2. One day before infection adherent cells were seeded onto sterile glass slides in 12-well plates while suspension cells were cultivated in 6-well plates.


id: cord-299428-gon6bzat
author: Mondal, Shankar
title: Sequence analysis of infectious bronchitis virus isolates from the 1960s in the United States
date: 2012-10-11
extension: .txt
mime: text/plain
words: 3278
sentence: 120
flesch: 50
cache: cache/cord-299428-gon6bzat.txt
txt: txt/cord-299428-gon6bzat.txt
summary:
  The BlastN program (http:// www.ncbi.nlm.nih.gov/BLAST/) was used to search GenBank for homologous IBV S1 and N gene sequences. Complete nucleotide analysis of the structural genome of the infectious bronchitis virus strain md27 reveals its mosaic nature Veterinary Microbiology Coronavirus avian infectious bronchitis virus Infectious Bronchitis Family Coronaviridae Infectious bronchitis virus types: incidence in the United States The evolution and emergence of RNA viruses Serologic and immunologic properties of a recent isolate of infectious bronchitis virus Recombinational histories of avian infectious bronchitis virus and turkey coronavirus Immune responses to structural proteins of avian infectious bronchitis virus Genetic and antigenic diversity in avian infectious bronchitis virus isolates of the 1940s Immunological differences in strains of infectious bronchitis virus Serotype identification of avian infectious bronchitis virus by RT-PCR of the peplomer (S1) gene Molecular cloning and sequence comparison of the S1 glycoprotein of the Gray and JMK strains of avian infectious bronchitis virus Redesign of primer and application of the reverse transcriptase-polymerase chain reaction and restriction fragment length polymorphism test to the DE072 strain of infectious bronchitis virus S1 glycoprotein gene analysis of infectious bronchitis viruses isolated in Korea Phylogenetic analysis of avian infectious bronchitis virus strains isolated in Japan Sequence analysis of the S1 glycoprotein of infectious bronchitis viruses: identification of a novel genotypic group in Australia An apparently new respiratory disease of chicks Complete nucleotide sequences of S1 and N genes of infectious bronchitis virus isolated in Japan and Taiwan Infectious bronchitis virus variants: a review of the history, current situation and control measures Evidence of natural recombination within the S1 gene of the infectious bronchitis virus Comparative analyses of the nucleocapsid genes of several strains of infectious bronchitis virus and other coronaviruses Sequence analysis of 1960s IBV isolates 503 Acknowledgements


id: cord-330035-0d6w8xyd
author: Jeon, Ji Hyun
title: Cellular cholesterol is required for porcine nidovirus infection
date: 2017-09-07
extension: .txt
mime: text/plain
words: 7687
sentence: 274
flesch: 36
cache: cache/cord-330035-0d6w8xyd.txt
txt: txt/cord-330035-0d6w8xyd.txt
summary:
  Taken together, our data indicate that cell membrane cholesterol is required for porcine nidovirus entry into cells, and pharmacological drugs that hamper cholesterol-dependent virus entry may have antiviral potential against porcine nidoviruses. Likewise, the present study indicated that pharmacological depletion of cellular cholesterol had no effect on the levels of pCD163 and pAPN expression in porcine cells.


id: cord-343780-084lq92r
author: Hsu, Tien-Huan
title: Detection, sequence analysis, and antibody prevalence of porcine deltacoronavirus in Taiwan
date: 2018-07-26
extension: .txt
mime: text/plain
words: 2088
sentence: 78
flesch: 53
cache: cache/cord-343780-084lq92r.txt
txt: txt/cord-343780-084lq92r.txt
summary:
  PDCoV-positive samples were further examined by traditional reverse transcription polymerase chain reaction (RT-PCR) with primers PDCoV-N1 (5'-ACC ATC GCT CCA AGT CAT TCTTG-3') and PDCoV-N2 (5'-GAG TGG AGT TGG GTG GGT TTA reverse-transcription reaction was performed at 50 °C for 30 minutes, and then a standard polymerase chain reaction was performed: 30 cycles of 94 °C (30 seconds), 55 °C (30 seconds), and 72 °C (1 minute). The nucleotide sequence data were analyzed using Chromas Lite, and the deduced amino acid sequences of the open reading frames were compared to other PDCoV sequences using BLAST.


id: cord-317009-8tqnt1l9
author: Aita, Tsunehiko
title: Characterization of epidemic diarrhea outbreaks associated with bovine torovirus in adult cows
date: 2011-12-14
extension: .txt
mime: text/plain
words: 3924
sentence: 156
flesch: 53
cache: cache/cord-317009-8tqnt1l9.txt
txt: txt/cord-317009-8tqnt1l9.txt
summary:
  In conclusion, we presented the epidemiological characteristics of BToV diarrhea in adult cattle based on three outbreaks in Niigata, Japan. Notably, no clinical signs, including diarrhea, were observed in calves during these outbreaks of adult cow diarrhea.


id: cord-339991-k8z6v2vx
author: Rong, Q.
date: 2003
extension: .txt
mime: text/plain
words: 5578
sentence: 204
flesch: 41
cache: cache/cord-339991-k8z6v2vx.txt
txt: txt/cord-339991-k8z6v2vx.txt
title:
  Multiple mechanisms for HSV-1 induction of interferon α production by peripheral blood mononuclear cells

summary:
  A MOI of 2 or the equivalent amount of UV-inactivated virus was chosen for the virus challenge because the cytopathological effect of infectious HSV on the different types of MOMC cells was minimal at this dose. Extensive symmetrical transcription of simian virus 40 DNA in virusyielding cells Interferon induction by HIV glycoprotein 120: role of the V3 loop Induction of interferon-alpha by glycoprotein D of herpes simplex virus: a possible role of chemokine receptors Dendritic cells and the control of immunity Granulocyte-macrophage colony-stimulating factor, interleukin-2, HSV-1 induction of IFN alpha in myeloid cells 341 interleukin-12 synergize with calcium ionophore to enhance dendritic cell function Role of early cytokines, including alpha and beta interferons (IFNalpha/beta), in innate and adaptive immune responses to viral infections Intrastrain variants of herpes simplex virus type 1 isolated from a neonate with fatal disseminated infection differ in the ICP34.5 gene, glycoprotein processing, and neuroinvasiveness Engagement of the cellular receptor for glycoprotein B of human cytomegalovirus activates the interferon-responsive pathway Linker-insertion nonsense and restriction-site deletion mutations of the gB glycoprotein gene of herpes simplex virus type 1 Recombinant glycoprotein 120 of human immunodeficiency virus is a potent interferon inducer Infrequent but efficient interferon-alpha-producing human mononuclear leukocytes induced by herpes simplex virus in vitro studied by immunoplaque and limiting dilution assays Interferons and the colony-stimulating factors IL-3 and GM-CSF enhance the ifn-alpha response in human blood leucocytes induced by herpes simplex virus Glycosylation is required for coronavirus TGEV to induce an efficient production of IFN-alpha by blood mononuclear cells IL-6


id: cord-332811-kjgah8ts
author: Lee, Do Hyun
date: 2015-06-23
extension: .txt
mime: text/plain
words: 5958
sentence: 208
flesch: 40
cache: cache/cord-332811-kjgah8ts.txt
txt: txt/cord-332811-kjgah8ts.txt
title:
  Immunoprophylactic effect of chicken egg yolk antibody (IgY) against a recombinant S1 domain of the porcine epidemic diarrhea virus spike protein in piglets

summary:
  The sections were then counterstained with DAPI and examined using a fluorescence microscope at 2009 magnification The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex Identification of the epitope region capable of inducing neutralizing antibodies against the porcine epidemic diarrhea virus Molecular characterization and phylogenetic analysis of membrane protein genes of porcine epidemic diarrhea virus isolates in China Isolation and characterization of porcine epidemic diarrhea viruses associated with the 2013 disease outbreak among swine in the United States Experimental infection of pigs with a new porcine enteric coronavirus, CV 777 Sequence of the spike protein of the porcine epidemic diarrhoea virus Detection of antibodies against porcine epidemic diarrhea virus in serum and colostrum by indirect ELISA Propagation of the virus of porcine epidemic diarrhea in cell culture Spike glycoprotein cleavage recognition site analysis of infectious bronchitis virus Multiplex real-time RT-PCR for the simultaneous detection and quantification of transmissible gastroenteritis virus and porcine epidemic diarrhea virus Isolation of porcine epidemic diarrhea virus (PEDV) in Korea Immunoprophylactic effect of chicken egg yolk immunoglobulin (IgY) against porcine epidemic diarrhea virus (PEDV) in piglets A method of egg yolk fractionation. Characterization of fractions Mutations within the nuclear localization signal of the porcine reproductive and respiratory syndrome virus nucleocapsid protein attenuate virus replication Heterogeneity in spike protein genes of porcine epidemic diarrhea viruses isolated in Korea The N-terminal region of the porcine epidemic diarrhea virus spike protein is important for the receptor binding Outbreak-related porcine epidemic diarrhea virus strains similar to US strains, South Korea Reemergence of porcine epidemic diarrhea virus on Jeju Island Full-genome sequence analysis of a variant strain of porcine epidemic diarrhea virus in South Korea Cytokine production in immortalized porcine alveolar macrophages infected with porcine reproductive and respiratory syndrome virus New variants of porcine epidemic diarrhea virus, China US-like strain of porcine epidemic diarrhea virus outbreaks in Taiwan Chicken egg yolk antibodies as therapeutics in enteric infectious disease: a review Deadly pig virus slips through US borders Contribution of the porcine aminopeptidase N (CD13) receptor density to porcine epidemic diarrhea virus infection Immunogenicity and protective efficacy of recombinant S1 domain of the porcine epidemic diarrhea virus spike protein Letter to the editor A new coronavirus-like particle associated with diarrhea in swine Porcine epidemic diarrhoea virus as a cause of persistent diarrhoea in a herd of breeding and finishing pigs Chinese-like strain of porcine epidemic diarrhea virus Porcine reproductive and respiratory syndrome virus nucleocapsid protein modulates interferon-b production by inhibiting IRF3 activation in immortalized porcine alveolar macrophages Human telomerase reverse transcriptase-immortalized porcine monomyeloid cell lines for the production of porcine reproductive and respiratory syndrome virus Diseases of swine Molecular cloning: a laboratory manual Emergence of Porcine epidemic diarrhea virus in the United States: clinical signs, lesions, and viral genomic sequences Proteolytic cleavage of peplomeric glycoprotein E2 of MHV yields two 90K subunits and activates cell fusion Spike protein region (aa 636789) of porcine epidemic diarrhea virus is essential for induction of neutralizing antibodies An outbreak of swine diarrhea of a new-type associated with coronavirus-like particles in Japan Acknowledgments This research was supported by Technology Development Program for Bio-Industry, Ministry for Agriculture, Food and Rural Affairs, Republic of Korea (311007-05-1-HD120).


id: cord-343256-n593kh7u
author: Percy, D. H.
date: 1991
extension: .txt
mime: text/plain
words: 1741
sentence: 72
flesch: 47
cache: cache/cord-343256-n593kh7u.txt
txt: txt/cord-343256-n593kh7u.txt
title:
  A comparison of the sensitivity and specificity of sialodacryoadenitis virus, Parker's rat coronavirus, and mouse hepatitis virus-infected cells as a source of antigen for the detection of antibody to rat coronaviruses

summary:
  Using SDAV- and PRC-infected L-2 cells as the source of antigen, and sera from rats collected post inoculation with either of these viral strains, the indirect fluorescent antibody (IFA) procedure was used to determine whether antibody titers could be used to differentiate infections from the homologous and heterologous virus. In addition, antibody titers were similar when mouse hepatitis virus (MHV)-infected cells were used as the source of antigen for the IFA technique.


id: cord-311773-r9c7sx6r
author: Gaertner, Diane J.
date: 1991
extension: .txt
mime: text/plain
words: 2676
sentence: 123
flesch: 53
cache: cache/cord-311773-r9c7sx6r.txt
txt: txt/cord-311773-r9c7sx6r.txt
title:
  Susceptibility of rodent cell lines to rat coronaviruses and differential enhancement by trypsin or DEAE-dextran

summary:
  Although many coronaviruses have fastidious growth requirements, replicating only in organ cultures or cell lines derived from the animal or tissue of origin, cell lines supporting growth of most coronaviruses have been identified [5, 7] . Cell lines received from extramural sources except the American Type Culture Collection were tested for Mycoplasma spp.


id: cord-325827-492xi3ee
author: Evermann, J. F.
date: 1988
extension: .txt
mime: text/plain
words: 4216
sentence: 152
flesch: 33
cache: cache/cord-325827-492xi3ee.txt
txt: txt/cord-325827-492xi3ee.txt
title:
  Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah

summary:
  In: Holzworth J (ed) Diseases of the cat Infection studies in kittens using feline infectious peritonitis virus propagated in cell culture An enteric coronavirus infection of cats and relationship to feline infectious peritonitis Pathogenicity studies of feline coronavirus isolates 79-1146 and 79-1683 Experimental studies with three new strains of feline infectious peritonitis virus: FIPV-UCD 2, FIPV-UCD 3 and FIPV-UCD 4 Eosinophilic ulcers in association with herpetic dermatitis in sibling cheetahs Feline infectious peritonitis in a captive cheetah Antibody-dependent enhancement of viral infectivity Infectious disease of nondomestic cats Experimentally induced coronavirus infections in calves: viral replication in the respiratory and intestinal tracts Dietary estrogen--a probable cause of infertility and liver disease in captive cheetahs Diagnosis of porcine and bovine enteric coronavirus infections using cloned cDNA probes The mutation rate and variability of eukaryotic viruses: an analytical review Intestinal, pulmonary, and serum antibody responses of feeder pigs exposed to transmissible gastroenteritis virus by the oral and the oralintranasal routes of inoculation Rapid evolution of RNA viruses Experimental studies of a coronavirus and coronavirus-like agent in a barrier-maintained feine breeding colony Proteolytic cleavage of the E 2 glycoprotein of murine coronavirus: activation of cell-fusing activity of virions by trypsin and separation of two different 90K cleavage fragments Role ofT cells in feline infectious peritonitis virus infection of suckling mice Trypsin-enhanced replication of neonatal calf diarrhea coronavirus in bovine embryonic lung cells Antigenic and biological diversity of feline coronaviruses: feline infectious peritonitis and feline enteritis virus Morphogenesis of a virus in cats with experimental feline infectiuos peritonitis Antibody-mediated enhancement of disease in feline infectious peritonitis: comparisons with dengue hemorrhagic fever Pathogenesis of feline infectious peritonitis: nature and development of viremia Proteases involved in the processing of viral polyproteins Viral interference-dominance of mutant viruses over wild-type viruses in mixed infections Feline infectious peritonitis: review of gross and histopathologic lesions Lesions in the small intestine of newborn pigs inoculated with porcine, feline and canine coronaviruses Feline coronavirus. key: cord-325827-492xi3ee authors: Evermann, J. F.; Heeney, J. L.; Roelke, M. E.; McKeirnan, A. J.; O'Brien, S. J. title: Biological and pathological consequences of feline infectious peritonitis virus infection in the cheetah date: 1988 journal: Arch Virol DOI: 10.1007/bf01310822 sha: doc_id: 325827 cord_uid: 492xi3ee


id: cord-333043-fe24ezt6
author: Traavik, T.
title: “Runde“ virus, a coronavirus-like agent associated with seabirds and ticks
date: 1977
extension: .txt
mime: text/plain
words: 4196
sentence: 220
flesch: 57
cache: cache/cord-333043-fe24ezt6.txt
txt: txt/cord-333043-fe24ezt6.txt
summary:
  This corona-like virus has been tentatively termed Runde virus. Circumstances of tickcollection strongly support that Runde virus is an arbovirus in the ecological sense, and not a mechanical pick-up : 1.


id: cord-341383-e2jrhycj
author: Dong, Wei
date: 2016-05-02
extension: .txt
mime: text/plain
words: 3352
sentence: 156
flesch: 50
cache: cache/cord-341383-e2jrhycj.txt
txt: txt/cord-341383-e2jrhycj.txt
title:
  Epidemiological and clinical characteristics of respiratory viral infections in children in Shanghai, China

summary:
  In this study, we investigated the prevalence and clinical characteristics of children with virus-related ARTIs and determined the spectrum of respiratory viruses and their correlation with meteorological variables in Jiading District, Shanghai, China. Nasopharyngeal swabs from 2819 children with ARTIs were collected from August 2011 to December 2014, and used for detection of respiratory viruses by multiplex RT-PCR.


id: cord-327855-txryqil7
author: Kulka, M.
title: The cytopathic 18f strain of Hepatitis A virus induces RNA degradation in FrhK4 cells
date: 2003
extension: .txt
mime: text/plain
words: 8717
sentence: 299
flesch: 43
cache: cache/cord-327855-txryqil7.txt
txt: txt/cord-327855-txryqil7.txt
summary:
  Degradation of rRNA has not been reported previously in HAV infected cells, therefore, the rRNA origin of the observed degradation The probe for 18S RNA was a 1.2 kb fragment of the mouse 18S The parental HM175/clone 1 virus (clone 1), also used in the present study, produced no changes in cell morphology after several months of continuous culture of infected cells, although viral antigens could be detected by EIA after four weeks of weekly subculture following the initial infection.


id: cord-339178-d6f6a5ds
author: Pensaert, M. B.
title: A new coronavirus-like particle associated with diarrhea in swine
date: 1978
extension: .txt
mime: text/plain
words: 1750
sentence: 79
flesch: 52
cache: cache/cord-339178-d6f6a5ds.txt
txt: txt/cord-339178-d6f6a5ds.txt
summary:
  Diarrhea was reproduced in experimental pigs with one of the isolates, designated CV777, which was found to be distinct from the 2 known porcine coronaviruses, transmissible gastroenteritis virus and hemagglutinating encephalomyelitis virus. Diarrhea was reproduced in experimental pigs with one of the isolates, designated CV777, which was found to be distinct from the 2 known porcine coronaviruses, transmissible gastroenteritis virus and hemagglutinating encephalomyelitis virus.


id: cord-290819-zhywlf6r
author: Wu, Jiaqi
date: 2020-07-27
extension: .txt
mime: text/plain
words: 4562
sentence: 197
flesch: 39
cache: cache/cord-290819-zhywlf6r.txt
txt: txt/cord-290819-zhywlf6r.txt
title:
  The antiviral protein viperin interacts with the viral N protein to inhibit proliferation of porcine epidemic diarrhea virus

summary:
  The antiviral protein viperin is a radical SAM enzyme Peroxisomes are signaling platforms for antiviral innate immunity Monkey viperin restricts porcine reproductive and respiratory syndrome virus replication Structural studies of viperin, an antiviral radical SAM enzyme Not just fat: the structure and function of the lipid droplet Cloning and sequence analysis of the N gene of porcine epidemic diarrhea virus LJB/03 Porcine epidemic diarrhea virus infection inhibits interferon signaling by targeted degradation of The role of viperin in the innate antiviral response In vivo and in vitro studies on the antiviral activities of viperin against influenza H1N1 virus infection Pathology of US porcine epidemic diarrhea virus strain PC21A in gnotobiotic pigs IFN-lambda preferably inhibits PEDV infection of porcine intestinal epithelial cells compared with IFN-alpha Immunological effects of different types of synthetic CpG oligodeoxynucleotides on porcine cells Porcine epidemic diarrhea virus infection induces NF-κB activation through the TLR2, TLR3 and TLR9 pathways in porcine intestinal epithelial cells Membrane curvature and mechanisms of dynamic cell membrane remodelling Type I interferons in infectious disease Contribution of the porcine aminopeptidase N (CD13) receptor density to porcine epidemic diarrhea virus infection Proteolytic activation of the porcine epidemic diarrhea coronavirus spike fusion protein by trypsin in cell culture Porcine epidemic diarrhea virus infects and replicates in porcine alveolar macrophages Isolation and characterization of porcine epidemic diarrhea viruses associated with the 2013 disease outbreak among swine in the United States Plasmacytoid dendritic cells: recent progress and open questions Antiviral protein viperin promotes toll-like receptor 7-and toll-like receptor 9-mediated type The cells were examined under an inverted fluorescence and phase-contrast microscope (Olympus) to determine the subcellular localization of viperin protein.


id: cord-315811-wpeac0lk
author: Hu, Hui
date: 2016-09-12
extension: .txt
mime: text/plain
words: 6550
sentence: 233
flesch: 52
cache: cache/cord-315811-wpeac0lk.txt
txt: txt/cord-315811-wpeac0lk.txt
title:
  Experimental infection of gnotobiotic pigs with the cell-culture-adapted porcine deltacoronavirus strain OH-FD22

summary:
  No villous atrophy or other histologic lesions were evident in the remainder of the small intestine, duodenum, and other organs of inoculated pigs 5 and 6 and negative control pig 8. When tested at PID 23-24, no IF-stained cells were detected in the villous epithelium of the small or large intestine of inoculated pigs 4 (P20) and 6 (P40).


id: cord-316525-uadfehr6
author: Zhang, X. W.
title: Testing the hypothesis of a recombinant origin of the SARS-associated coronavirus
date: 2004-10-11
extension: .txt
mime: text/plain
words: 3026
sentence: 101
flesch: 41
cache: cache/cord-316525-uadfehr6.txt
txt: txt/cord-316525-uadfehr6.txt
summary:
  The mutation analysis of sequence variations among these isolates will help identify the genetic signature of SARS virus strains when a sufficient amount of sequence data is available. The left panels stand for non-recombination regions and the right panels for recombination regions.


id: cord-344464-if6js43s
author: Cowley, J. A.
date: 2002
extension: .txt
mime: text/plain
words: 3525
sentence: 125
flesch: 45
cache: cache/cord-344464-if6js43s.txt
txt: txt/cord-344464-if6js43s.txt
title:
  The complete genome sequence of gill-associated virus of Penaeus monodon prawns indicates a gene organisation unique among nidoviruses(*): Brief Report

summary:
  Prediction of mucin type O-glycosylation sites based on sequence context and surface accessibility Evidence for a separate signal sequence for the carboxy-terminal envelope glycoprotein E1 of Semliki Forest virus TMbase -A database of membrane spanning protein segments Complete sequence of the glycoproteins and M RNA of Punta Toro phlebovirus compared to those of Rift Valley fever virus A simple method for displaying the hydropathic character of a protein Coronavirus: organization, replication and expression of genome The molecular biology of coronaviruses Handbook for cultivation of black tiger prawns Predicting coiled coils from protein sequences Yellow-head virus: A rhabdovirus-like pathogen of penaeid shrimp Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural protein Complete nucleotide sequence of the M RNA segment of Uukuniemi virus encoding the membrane glycoproteins G1 and G2 Molecular cloning: a laboratory manual A new model for coronavirus transcription A phosphatocopid crustacean with appendages from the Lower Cambrian Identification and primary structure of the gene encoding the Berne virus nucleocapsid protein Primary structure and post-translational processing of the Berne virus peplomer protein A 3 -coterminal nested set of independently transcribed mRNAs is generated during Berne virus replication The molecular biology of arteriviruses A hidden Markov model for predicting transmembrane helices in protein sequences Proc Sixth International Conference on Intelligent Systems for Molecular Biology Lymphoid organ virus of Penaeus monodon from Australia Gill-associated virus (GAV), a yellow head-like virus from Penaeus monodon cultured in Australia A yellow head virus probe: application to in situ hybridization and determination of its nucleotide sequence Arterivirus discontinuous mRNA transcription is guided by base pairing between sense and antisense transcription-regulating sequences Yellow head complex viruses: transmission cycles an topographical distribution in the Asia-Pacific region Yellow head virus infection in the giant tiger prawn Penaeus monodon cultured in Taiwan Yellow-head virus of Penaeus monodon is an RNA virus Author's address: Jeff Cowley, CSIRO Livestock Industries, 120 Meiers Road We kindly thank Dr. Sigrid Lehnert for providing the prawn cDNA phage library and Dr. Ross Tellam for helpful discussions on glycoprotein processing. The S glycoprotein gene of coronaviruses encodes polypeptides that range in size from 1160 aa for Infectious bronchitis virus [3] to 1452 aa for Feline infectious peritoneal virus [11] , while the cognate genes of the toroviruses Berne virus and Breda virus [14, 35] encode polypeptides (1581-1583 aa) approaching the size of GAV ORF3.


id: cord-321195-cndq6aqb
author: Xue, Chunyi
date: 2014-07-27
extension: .txt
mime: text/plain
words: 4558
sentence: 187
flesch: 45
cache: cache/cord-321195-cndq6aqb.txt
txt: txt/cord-321195-cndq6aqb.txt
title:
  Chimeric influenza-virus-like particles containing the porcine reproductive and respiratory syndrome virus GP5 protein and the influenza virus HA and M1 proteins

summary:
  The receptor-binding and membrane-fusion properties of influenza virus variants selected using anti-haemagglutinin monoclonal antibodies Expression of codon optimized major capsid protein (L1) of human papillomavirus type 16 and 18 in Pichia pastoris; purification and characterization of the virus-like particles Influenza-pseudotyped Gag virus-like particle vaccines provide broad protection against highly pathogenic avian influenza challenge Molecular basis for the generation in pigs of influenza a viruses with pandemic potential Influenza virus-like particles as pandemic vaccines Influenza vaccines based on virus-like particles Production and characterization of virus-like particles and the P domain protein of GII.4 norovirus Formation of wild-type and chimeric influenza virus-like particles following simultaneous expression of only four structural proteins Genomic analysis of two Chinese strains of porcine reproductive and respiratory syndrome viruses with different virulence Enterovirus type 71 neutralizing antibodies in the serum of macaque monkeys immunized with EV71 virus-like particles Chimeric severe acute respiratory syndrome coronavirus (SARS-CoV) S glycoprotein and influenza matrix 1 efficiently form virus-like particles (VLPs) that protect mice against challenge with SARS-CoV Assembly and immunological properties of Newcastle disease virus-like particles containing the respiratory syncytial virus F and G proteins Assembly and biological and immunological properties of Newcastle disease virus-like particles Newcastle disease virus-like particles containing respiratory syncytial virus G protein induced protection in BALB/c mice, with no evidence of immunopathology Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United States Virus-like particles as immunogens Immunogenicity and specificity of norovirus Consensus GII.4 virus-like particles in monovalent and bivalent vaccine formulations Clinical signs and economic losses caused by porcine reproductive and respiratory syndrome virus in a large breeding farm Intranasal vaccination with 1918 influenza virus-like particles protects mice and ferrets from lethal 1918 and H5N1 influenza virus challenge Chinese-like strain of porcine epidemic diarrhea virus Recombinant H1N1 virus-like particle vaccine elicits protective immunity in ferrets against the 2009 pandemic H1N1 influenza virus Influenza virus-like particle can accommodate multiple subtypes of hemagglutinin and protect from multiple influenza types and subtypes Influenza virus-like particles comprised of the HA, NA, and M1 proteins of H9N2 influenza virus induce protective immune responses in BALB/c mice Virus-like particle vaccine induces protective immunity against homologous and heterologous strains of influenza virus A bivalent influenza VLP vaccine confers complete inhibition of virus replication in lungs A trivalent virus-like particle vaccine elicits protective immune responses against seasonal influenza strains in mice and ferrets Porcine reproductive and respiratory syndrome Immunology of the porcine respiratory disease complex Production and immunogenicity of chimeric virus-like particles containing porcine reproductive and respiratory syndrome virus GP5 protein Virus-like particles of hepatitis B virus core protein containing five mimotopes of infectious bursal disease virus (IBDV) protect chickens against IBDV Fabrication of influenza virus-like particles using M2 fusion proteins for imaging single viruses and designing vaccines Vaccination with coxsackievirus B3 virus-like particles elicits humoral immune response and protects mice against myocarditis Vaccination has been an effective way to reduce the incidence of diseases resulting from influenza virus and PRRSV infections.


id: cord-347443-0evqo01m
author: Litwin, Christine M.
date: 2013-07-24
extension: .txt
mime: text/plain
words: 3999
sentence: 182
flesch: 46
cache: cache/cord-347443-0evqo01m.txt
txt: txt/cord-347443-0evqo01m.txt
title:
  Seasonality and prevalence of respiratory pathogens detected by multiplex PCR at a tertiary care medical center

summary:
  respiratory viral panels for the diagnosis of respiratory viral infections in adults Performance of a novel microarray multiplex PCR for the detection of 23 respiratory pathogens (SYMP-ARI study) Prospective evaluation of a novel multiplex real-time PCR assay for detection of fifteen respiratory pathogens-duration of symptoms significantly affects detection rate Seasonal variations of 15 respiratory agents illustrated by the application of a multiplex polymerase chain reaction assay Respiratory infections by HMPV and RSV are clinically indistinguishable but induce different host response in aged individuals Provisional Pertussis Surveillance Report Burden of human metapneumovirus infection in young children Human metapneumovirus infections-biannual epidemics and clinical findings in children in the region of Basel, Switzerland Broad respiratory virus detection in infants hospitalized for bronchiolitis by use of a multiplex RT-PCR DNA microarray system Prevalence of human metapneumovirus in adults with acute respiratory tract infection in Beijing Comparison of viral isolation and multiplex real-time reverse transcription-PCR for confirmation of respiratory syncytial virus and influenza virus detection by antigen immunoassays Prospective controlled study of four infection-control procedures to prevent nosocomial infection with respiratory syncytial virus Seasonality of respiratory tract infections 71 Seasonality, incidence, and repeat human metapneumovirus lower respiratory tract infections in an area with a high prevalence of human immunodeficiency virus type-1 infection Detection of respiratory viruses by molecular methods The Tecumseh study of respiratory illness. RSV and hMPV were the second-and third-most common causes of respiratory infections in our study.


id: cord-341278-klv9jdm8
author: Smith, Abigail L.
title: The role of gamma interferon in infection of susceptible mice with murine coronavirus, MHV-JHM
date: 1991
extension: .txt
mime: text/plain
words: 3874
sentence: 149
flesch: 40
cache: cache/cord-341278-klv9jdm8.txt
txt: txt/cord-341278-klv9jdm8.txt
summary:
  Since gamma interferon (IFN) has been implicated as an up-regulator of IgG 2 a production, attempts were made to determine whether levels of this cytokine were modified in sera of infected mice. Based on the observation of elevated ovalbumin (OVA)-specific IgG 2 a levels in sera of mice infected with MHV-JHM at any of several intervals relative to antigen exposure, attempts were made to detect IFN-7 in sera of infected mice and to reverse the IgG 2 a elevation by administration of IFN-y-specific antibody.


id: cord-340905-8nyew5i5
author: Chen, Yi-Ning
date: 2015-08-08
extension: .txt
mime: text/plain
words: 3194
sentence: 107
flesch: 44
cache: cache/cord-340905-8nyew5i5.txt
txt: txt/cord-340905-8nyew5i5.txt
title:
  Genotyping of turkey coronavirus field isolates from various geographic locations in the Unites States based on the spike gene

summary:
  The S gene sequences of different TCoV isolates (93 %-99.7 %) are more conserved than those of various IBV strains (67.4 %-94.4 %), which could explain the close antigenic relationship of TCoV isolates compared with the distant antigenicity of different IBV serotypes [5, 10, 13, 14] . Comparisons of 3'-end coding regions [9, 10] as well as the full genomes [11] of TCoV isolates and infectious bronchitis virus (IBV) have suggested that TCoV arises through recombination in the S gene, because pairwise comparisons of S gene sequences have revealed only a 34 % similarity between TCoV isolates and IBV strains, whereas gene 3, M gene, gene 5, and N gene sequences have over 80 % similarity [9, 11, 12] .


id: cord-314069-8dxzf2ip
author: Dongliu, Yuan
date: 2016-06-28
extension: .txt
mime: text/plain
words: 4291
sentence: 177
flesch: 48
cache: cache/cord-314069-8dxzf2ip.txt
txt: txt/cord-314069-8dxzf2ip.txt
title:
  Outbreak of acute febrile respiratory illness caused by human adenovirus B P14H11F14 in a military training camp in Shandong China

summary:
  Some earlier statistical analyses have shown that marching training and firing training are significantly associated with the onset of pneumonia and FRI, especially in HAdV outbreaks To investigate the genetic relationships between isolate SD77001 and other HAdV strains, phylogenetic trees were constructed by the maximum-likelihood method with 1000 bootstrap pseudoreplicates using the MEGA 5 program [18] .


id: cord-355535-01h8yyqj
author: Zheng, Xue-yan
date: 2018-01-11
extension: .txt
mime: text/plain
words: 3292
sentence: 158
flesch: 37
cache: cache/cord-355535-01h8yyqj.txt
txt: txt/cord-355535-01h8yyqj.txt
title:
  Regional, age and respiratory-secretion-specific prevalence of respiratory viruses associated with asthma exacerbation: a literature review

summary:
  The global burden of asthma: executive summary of the GINA Dissemination Committee Report Global, regional, and national deaths, prevalence, disabilityadjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015: a systematic analysis for the Global Burden of Disease Study Community study of role of viral infections in exacerbations of asthma in 9-11 year old children Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies Burden of disease and circulating serotypes of rotavirus infection in sub-Saharan Africa: systematic review and meta-analysis Meta-analysis in clinical trials Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance Prevalence of rhinoviruses in young children of an unselected birth cohort from the Netherlands Prevalence of non-influenza respiratory viruses in acute respiratory infection cases in Mexico The epidemiology of medically attended respiratory syncytial virus in older adults in the United States: a systematic review Epidemiology of sepsis-like illness in young infants: major role of enterovirus and human parechovirus Infections and coinfections by respiratory human bocavirus during eight seasons in hospitalized children EV-D68 infection in children with asthma exacerbation and pneumonia in Mexico City during Network New Vaccine Surveillance (2013) Burden of human metapneumovirus infection in young children Rhinovirus-induced first wheezing episode predicts atopic but not nonatopic asthma at school age RSV Global Epidemiology Network (2017) Global, regional and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study Detection of respiratory syncytial virus (RSV) at birth in a newborn with respiratory distress Frequent detection and genetic diversity of human bocavirus in urban sewage samples Modelling person-to-person transmission in an Enterovirus A71 orally infected hamster model of hand-foot-and-mouth disease and encephalomyelitis High-throughput, sensitive, and accurate multiplex PCR-microsphere flow cytometry system for large-scale comprehensive detection of respiratory viruses Prospective comparison of the detection rates of human enterovirus and parechovirus RT-qPCR and viral culture in different pediatric specimens Bronchial mucus transport Pathological changes in virus infections of the lower respiratory tract in children Structure and function of the polymeric mucins in airways mucus The role of viruses in acute exacerbations of asthma Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling Shotgun proteomic analysis of humaninduced sputum Respiratory Syncytial Virus Network (ReSViNET) (2015) Lower respiratory tract infection caused by respiratory syncytial virus: current management and new therapeutics Enterovirus 68 infection-association with asthma Study Group (2017) Sixty articles (63 studies) were analyzed to assess the association of virus infection with asthma exacerbations.


id: cord-345957-wuk2arf9
author: Mohamed, Fakry F.
title: Detection and genetic characterization of bovine kobuvirus from calves in Egypt
date: 2018-02-08
extension: .txt
mime: text/plain
words: 4254
sentence: 187
flesch: 58
cache: cache/cord-345957-wuk2arf9.txt
txt: txt/cord-345957-wuk2arf9.txt
summary:
  BKoV VP1 sequences from Egypt belonged to lineage 1 (Genotype A), which includes BKoVs from Brazil, Japan (only U-1 strain), and Scotland. Based on phylogenetic analysis of 35 GenBank reference strains, BKoV sequences from Cairo (n = 5) clustered with Chinese strains Table 2


id: cord-338607-22f04uqe
author: Verbeek, A.
date: 1991
extension: .txt
mime: text/plain
words: 4132
sentence: 150
flesch: 41
cache: cache/cord-338607-22f04uqe.txt
txt: txt/cord-338607-22f04uqe.txt
title:
  Genomic relationship between turkey and bovine enteric coronaviruses identified by hybridization with BCV or TCV specific cDNA probes

summary:
  In conclusion, BCV or TCV probes may be valuable in molecular hybridization for routine clinical diagnosis of either virus but may be problematic when these two viruses have to be distinguished. Double-stranded probes, synthesized in PCR with 1/3 of the dCTP being radiolabelled were efficient in BCV detection but resulted in strong background after only 8 h of autoradiography


id: cord-349800-s9w2yr08
author: Hohdatsu, T.
date: 1991
extension: .txt
mime: text/plain
words: 3080
sentence: 124
flesch: 52
cache: cache/cord-349800-s9w2yr08.txt
txt: txt/cord-349800-s9w2yr08.txt
title:
  Characterization of monoclonal antibodies against feline infectious peritonitis virus type II and antigenic relationship between feline, porcine, and canine coronaviruses

summary:
  key: cord-349800-s9w2yr08 authors: Hohdatsu, T.; Okada, S.; Koyama, H. title: Characterization of monoclonal antibodies against feline infectious peritonitis virus type II and antigenic relationship between feline, porcine, and canine coronaviruses date: 1991 journal: Arch Virol DOI: 10.1007/bf01310494 sha: doc_id: 349800 cord_uid: s9w2yr08 Seven monoclonal antibodies (MAbs) with neutralizing activity against feline infectious peritonitis virus (FIPV) strain 79-1149 (type II) were prepared. The second antigenic group consists of human respiratory coronavirus HCV-229E, transmissible gastroenteritis virus (TGEV) of swine, canine coronavirus (CCV), and feline infectious peritonitis virus (FIPV)


id: cord-334810-hw1aijwf
author: Banyard, Ashley C.
date: 2009-10-20
extension: .txt
mime: text/plain
words: 1965
sentence: 69
flesch: 47
cache: cache/cord-334810-hw1aijwf.txt
txt: txt/cord-334810-hw1aijwf.txt
title:
  Repeated detection of European bat lyssavirus type 2 in dead bats found at a single roost site in the UK

summary:
  Bats: important reservoir hosts of emerging viruses European bat lyssavirus type 2: human exposure in England European bat lyssaviruses: an emerging zoonosis Detection of high levels of European bat lyssavirus type-1 viral RNA in the thyroid gland of experimentally infected Eptesicus fuscus bats Susceptibility of North American big brown bats (Eptesicus fuscus) to infection with European bat lyssavirus type 1 First isolation of EBLV-2 in Germany Experimental infection of Serotine bats (Eptesicus serotinus) with European bat lyssavirus type 1a (EBLV-1a) Isolation of European bat lyssavirus type 2 from a Daubenton's bat (Myotis daubentonii) in Shropshire Antibodies against Lagos bat virus in megachiroptera from West Africa Heminested PCR assay for detection of six genotypes of rabies and rabies-related viruses Experimental infection of big brown bats (Eptesicus fuscus) with Eurasian bat lyssaviruses Aravan, Khujand, and Irkut virus Isolation of a European bat lyssavirus type 2 from a Daubenton's bat in the United Kingdom Airbourne transmission of lyssaviruses Experimental study of European bat lyssavirus type-2 infection in Daubenton's bats (Myotis daubentonii) Experimental infection of big brown bats (Eptesicus fuscus) with West Caucasian bat virus (WCBV) Influence of the gravid state Rabies in individual countries-Denmark Prevalence and genetic diversity of coronaviruses in bats from China Natural and experimental infection of sheep with European bat lyssavirus type-1 of Danish bat origin European bat lyssaviruses European bat lyssaviruses-an ecological enigma Development of a real-time, differential RT-PCR TaqMan assay for lyssavirus genotypes 1, 5 and 6 First isolation of a rabies-related virus from a Daubenton's bat in the United Kingdom Detection of diverse astroviruses from bats in China Acknowledgments We wish to acknowledge Denise Marston for technical assistance.


id: cord-317617-snrumw3x
author: Sugiyama, K.
date: 1981
extension: .txt
mime: text/plain
words: 2708
sentence: 190
flesch: 70
cache: cache/cord-317617-snrumw3x.txt
txt: txt/cord-317617-snrumw3x.txt
title:
  Morphological and biological properties of a new coronavirus associated with diarrhea in infant mice

summary:
  key: cord-317617-snrumw3x authors: Sugiyama, K.; Amano, Y. title: Morphological and biological properties of a new coronavirus associated with diarrhea in infant mice date: 1981 journal: Arch Virol DOI: 10.1007/bf01318134 sha: doc_id: 317617 cord_uid: snrumw3x Biological and morphological properties of a virus, isolated from the intestine of infant mice with clinical signs of diarrhea and designated as diarrhea virus of infant mice (DVIM), were examined. I n f e c t e d cell cultures on coverslips were fixed


id: cord-322593-bgm6smuo
author: Li, Lan
date: 2016-04-21
extension: .txt
mime: text/plain
words: 4719
sentence: 172
flesch: 47
cache: cache/cord-322593-bgm6smuo.txt
txt: txt/cord-322593-bgm6smuo.txt
title:
  Antiviral activity of recombinant porcine surfactant protein A against porcine reproductive and respiratory syndrome virus in vitro

summary:
  Porcine reproductive and respiratory syndrome virus vaccine does not fit in classical vaccinology Porcine reproductive and respiratory syndrome Porcine reproductive and respiratory syndrome virus-infected alveolar macrophages contain no detectable levels of viral proteins in their plasma membrane and are protected against antibody-dependent, complement-mediated cell lysis Expression and antibody preparation of GP5a gene of porcine reproductive and respiratory syndrome virus North American and European porcine reproductive and respiratory syndrome viruses differ in nonstructural protein coding regions Inactivated and subunit vaccines against porcine reproductive and respiratory syndrome: current status and future direction Pathogenesis of porcine reproductive and respiratory syndrome virus Characterization of proteins encoded by ORFs 2 to 7 of Lelystad virus Discovery of a small arterivirus gene that overlaps the GP5 coding sequence and is important for virus production Identification of a novel structural protein of arteriviruses Identification and characterization of a sixth structural protein of Lelystad virus: the glycoprotein GP2 encoded by ORF2 is incorporated in virus particles A 10-kDa structural protein of porcine reproductive and respiratory syndrome virus encoded by ORF2b Novel structural protein in porcine reproductive and respiratory syndrome virus encoded by an alternative ORF5 present in all arteriviruses Live porcine reproductive and respiratory syndrome virus vaccines: current status and future direction Failure of an inactivated vaccine against porcine reproductive and respiratory syndrome to protect gilts against a heterologous challenge with PRRSV Assessment of the efficacy of commercial porcine reproductive and respiratory syndrome virus (PRRSV) vaccines based on measurement of serologic response, frequency of gamma-IFN-producing cells and virological parameters of protection upon challenge Inhibition of porcine reproductive and respiratory syndrome virus replication by flavaspidic acid AB Antiviral activity and underlying molecular mechanisms of Matrine against porcine reproductive and respiratory syndrome virus in vitro Natural compounds inhibiting the replication of Porcine reproductive and respiratory syndrome virus Suppression of porcine reproductive and respiratory syndrome virus proliferation by glycyrrhizin LiCl inhibits PRRSV infection by enhancing Wnt/beta-catenin pathway and suppressing inflammatory responses Poly(I:C) inhibits porcine reproductive and respiratory syndrome virus replication in MARC-145 cells via activation of IFIT3 Antiviral activity of type I and type III interferons against porcine reproductive and respiratory syndrome virus (PRRSV) DRACO inhibits porcine reproductive and respiratory syndrome virus replication in vitro MicroRNA-23 inhibits PRRSV replication by directly targeting PRRSV RNA and possibly by upregulating type I interferons Surfactant proteins SP-A and SP-D: structure, function and receptors Surfactant protein A binds to the fusion glycoprotein of respiratory syncytial virus and neutralizes virion infectivity Recombinant porcine lung surfactant protein A inhibits porcine reproductive and respiratory syndrome virus infection into host cells in vitro Surfactant protein D inhibits HIV-1 infection of target cells via interference with gp120-CD4 interaction and modulates pro-inflammatory cytokine production Porcine plasma ficolin binds and reduces infectivity of porcine reproductive and respiratory syndrome virus (PRRSV) in vitro In vitro anti-herpes simplex virus activity of 1,2,4,6-tetra-O-galloyl-b-Dglucose from Phyllanthus emblica L. (Euphorbiaceae) Large-molecular-weight carbohydrate-binding agents as HIV entry inhibitors targeting glycoprotein gp120 Inhibition of HIV entry by carbohydratebinding proteins Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle Assessment of the antiviral properties of recombinant porcine SP-D against various influenza A viruses in vitro Entry of hepatitis C virus and human immunodeficiency virus is selectively inhibited by carbohydratebinding agents but not by polyanions Effects of origin and state of differentiation and activation of monocytes/macrophages on their susceptibility to porcine reproductive and respiratory syndrome virus (PRRSV) Surfactant protein A (SP-A) belongs to the family of C-type lectins, which can exert antiviral activities.


id: cord-341469-7guojyay
author: Park, Seong-Jun
date: 2011-01-06
extension: .txt
mime: text/plain
words: 3721
sentence: 126
flesch: 46
cache: cache/cord-341469-7guojyay.txt
txt: txt/cord-341469-7guojyay.txt
title:
  Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field isolates in Korea

summary:
  The nucleotide sequences of the full-length M and ORF3 genes of Korean PEDV field isolates were aligned using ClustalX version 1.83 Sequences of complete ORF3 genes of Korean PEDV field isolates were determined and compared to those of other PEDV reference strains.


id: cord-356176-1nwjjgul
author: Atherton, J. G.
date: 1978
extension: .txt
mime: text/plain
words: 1753
sentence: 70
flesch: 51
cache: cache/cord-356176-1nwjjgul.txt
txt: txt/cord-356176-1nwjjgul.txt
title:
  The effect of ascorbic acid on infection of chick-embryo ciliated tracheal organ cultures by coronavirus

summary:
  The final observation was made after 4 days incubation and cilial activity reduced to 1 + or less taken as evidence of virus infection. A lower titre for virus infectivity end-point in treated cells compared with untreated cells, indicating a decrease in plating efficiency, was taken as evidence of increased resistance of the treated cells to virus infection.


id: cord-346321-drhiqch0
author: Hohdatsu, T.
date: 1994
extension: .txt
mime: text/plain
words: 3733
sentence: 128
flesch: 47
cache: cache/cord-346321-drhiqch0.txt
txt: txt/cord-346321-drhiqch0.txt
title:
  The role of IgG subclass of mouse monoclonal antibodies in antibody-dependent enhancement of feline infectious peritonitis virus infection of feline macrophages

summary:
  key: cord-346321-drhiqch0 authors: Hohdatsu, T.; Tokunaga, J.; Koyama, H. title: The role of IgG subclass of mouse monoclonal antibodies in antibody-dependent enhancement of feline infectious peritonitis virus infection of feline macrophages date: 1994 journal: Arch Virol DOI: 10.1007/bf01310791 sha: doc_id: 346321 cord_uid: drhiqch0 Antibody-dependent enhancement (ADE) of feline infectious peritonitis virus (FIPV) infection was studied in feline alveolar macrophages and human monocyte cell line U937 using mouse neutralizing monoclonal antibodies (MAbs) directed to the spike protein of FIPV. I. Infection enhancement by nonneutralizing antibody Heterogeneity of infection enhancement of dengue 2 strains by monoclonal antibodies Characterization of monoelonal antibodies against feline infectious peritonitis virus type II and antigenic relationship between feline, porcine and canine coronaviruses A study on the mechanism of antibody-dependent enhancement of feline infectious peritonitis virus infection in feline macrophages by monoctonal antibodies Enhancement and neutralization of feline infectious peritonitis virus infection in feline macrophages by neutralizing monoclonal antibodies recognizing different epitopes Studies on the mechanism of antibody-mediated enhancement of Getah virus infectivity Human monocytes and U937 cells bear two distinct Fc receptors for IgG Neuraminidase augments Fc y receptor II-mediated antibody-dependent enhancement of dengue virus infection Dengue 4 virus monoctonal antibodies identify epitopes that mediate immune infection enhancement of dengue 2 viruses Antibody-mediated growth of influenza A NWS virus in macrophagelike cell line P388D1 Identification of antigenic sites mediating antibody-dependent enhancement of feline infectious peritonitis virus infectivity Monoclonal antibodies to the spike protein of feline infectious peritonitis virus mediate antibodydependent enhancement of infection of feline macrophages Attempted immunization of cats against feline infectious peritonitis, using avirulent live virus or sublethal amounts of virulent virus Immunologic phenomena in the effusive form of feline infectious peritonitis Pathogenicity studies of feline coronavirus isolates 79-1146 and 79-1683 An enteric coronavirus infection of cats and its relationship to feline infectious peritonitis Virologic and immunologic aspects of feline infectious peritonitis virus infection Antibody-mediated enhancement of flavivirus replication in macrophage-like cell lines Growth of 17 D yellow fever virus in a macrophage-like cell line, U937: role of Fc and viral receptors in antibody-mediated infection Feline immunoglobulins Attempted immunisation of cats against feline infectious peritonitis using canine coronavirus The sites of early viral replication in feline infectious peritonitis Antibody-enhanced infection by HIV-1 via Fc receptor-mediated entry Function and heterogeneity of human Fc receptors for immunoglobulin G Early death after feline infectious peritonitis virus challenge due to recombinant vaccinia virus immunization Antibody-mediated enhancement of disease in feline infectious peritonitis: comparisons with dengue hemorrhagic fever Cross-protection studies between feline infectious peritonitis and porcine transmissible gastroenteritis viruses This work was supported by private contributions of Sankyo Co., Ltd., Ajinomoto General Foods, Inc. and Dainippon Pharmaceutical Co., Ltd., Japan.


id: cord-348147-leni23pa
author: Müller, B.
title: Genetic diversity and recombination of murine noroviruses in immunocompromised mice
date: 2007-05-29
extension: .txt
mime: text/plain
words: 3493
sentence: 158
flesch: 47
cache: cache/cord-348147-leni23pa.txt
txt: txt/cord-348147-leni23pa.txt
summary:
  Amplification of partial ORF1 and ORF2 sequences ORF1 (RNA polymerase region) and ORF2 (capsid) were amplified by nested RT-PCRs. However, the divergences of partial ORF1 and ORF2 sequences of MNV isolates investigated here reveal a high degree of variability among murine noroviruses.


id: cord-340065-f4ffvkr9
author: Horváth, Trén
date: 1981
extension: .txt
mime: text/plain
words: 2713
sentence: 177
flesch: 64
summary: T h e n e u t r a l T h e n e u t r a l
cache: cache/cord-340065-f4ffvkr9.txt
txt: txt/cord-340065-f4ffvkr9.txt
title:
  Ultrastructural changes in the small intestinal epithelium of suckling pigs affected with a transmissible gastroenteritis (TGE)-like disease


id: cord-346629-770qyee8
author: Mase, M.
title: Phylogenetic analysis of avian infectious bronchitis virus strains isolated in Japan
date: 2004-07-15
extension: .txt
mime: text/plain
words: 2367
sentence: 109
flesch: 46
cache: cache/cord-346629-770qyee8.txt
txt: txt/cord-346629-770qyee8.txt
summary:
  In this study, prevalent IBV genetic groups in Japan were shown to be completely distinct from other known serotypes from Europe and North America by comparing amino acid sequences of the N-terminus in the S1 glycoprotein. Classically, IBV strains have been placed into serologically related groups on the basis of virus neutralization tests (VNT).


id: cord-333331-ddcz7zck
author: Yang, Jin
title: Detection of hepatitis C virus by an improved loop-mediated isothermal amplification assay
date: 2011-05-12
extension: .txt
mime: text/plain
words: 5212
sentence: 220
flesch: 51
cache: cache/cord-333331-ddcz7zck.txt
txt: txt/cord-333331-ddcz7zck.txt
summary:
  Adding AP to the Principle of AP in LAMP amplification. When comparing the electrophoresis bands of the products of the AP-LAMP, AP-B3 LAMP and Pre-LAMP assays, the first two showed a similar pattern.


id: cord-335690-66t5fjld
author: Khromykh, A. A.
title: RNA binding properties of core protein of the flavivirus Kunjin
date: 1996
extension: .txt
mime: text/plain
words: 5871
sentence: 182
flesch: 49
cache: cache/cord-335690-66t5fjld.txt
txt: txt/cord-335690-66t5fjld.txt
summary:
  RNA binding domains within capsid proteins and involving enrichment in basic amino acids have been analysed for several positive-stranded RNA viruses, including the BMV CP discussed above [6] . SDS-PAGE analysis of purified KUN core-fusion proteins (see Fig. la ) and their use in competition RNA binding experiments between 5' core RNA and tRNA.


id: cord-355512-tycuoslv
author: Storz, J.
date: 1992
extension: .txt
mime: text/plain
words: 3259
sentence: 136
flesch: 52
cache: cache/cord-355512-tycuoslv.txt
txt: txt/cord-355512-tycuoslv.txt
title:
  Comparison of hemagglutinating, receptor-destroying, and acetylesterase activities of avirulent and virulent bovine coronavirus strains

summary:
  Diisopropylfluorophosphate (DFP) was used as an inhibitor of serine esterase activity to assess the effect of AE from different BCV strains on the HA and RDE functions as well as on BCV infectivity. Acetylesterase activity of purified BCV preparations was determined according to Vlasak et al.


id: cord-346928-g1dqiki6
author: Costantini, V.
date: 2003-11-26
extension: .txt
mime: text/plain
words: 5903
sentence: 219
flesch: 51
cache: cache/cord-346928-g1dqiki6.txt
txt: txt/cord-346928-g1dqiki6.txt
title:
  Respiratory and fecal shedding of Porcine respiratory coronavirus (PRCV) in sentinel weaned pigs and sequence of the partial S-gene of the PRCV isolates

summary:
  In preliminary studies, inoculation of gnotobiotic pigs with each plaque-purified pair of the nasal and fecal PRCV isolates, revealed no clinical disease but different tropisms. In contrast TGEV strains have an intact S-gene.


id: cord-345552-h6fwi0qn
author: Li, Q.-G.
title: Hydropathic characteristics of adenovirus hexons
date: 1997-07-01
extension: .txt
mime: text/plain
words: 3524
sentence: 160
flesch: 48
cache: cache/cord-345552-h6fwi0qn.txt
txt: txt/cord-345552-h6fwi0qn.txt
summary:
  Every hexon DNA sequence was translated to protein sequence by using program EditSeq-Translation. Here, we report the hydropathy analysis of 14 adenovirus hexon sequences predicted from a newly determined Ad7 hexon DNA sequence and thirteen published hexon sequences of Ad2, Ad3, Ad4, Ad5, Ad12, Ad16, Ad40, Ad41, Ad48, Bav3, Mav1, Fav1 and Fav10.


id: cord-341342-kyavg4vu
author: Masters, P. S.
date: 1992
extension: .txt
mime: text/plain
words: 5909
sentence: 213
flesch: 50
cache: cache/cord-341342-kyavg4vu.txt
txt: txt/cord-341342-kyavg4vu.txt
title:
  Localization of an RNA-binding domain in the nucleocapsid protein of the coronavirus mouse hepatitis virus

summary:
  Interferon-mediated inhibition of simian virus-40 early RNA accumulation Zinc fingers: a novel protein motif for nucleic acid recognition Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Characterization of leader RNA sequences on the virion and mRNAs of mouse hepatitis virus, a cytoplasmic RNA virus Sequence-specific recognition of RNA hairpins by bacteriophage antiterminators requires a conserved arginine-rich motif The complete sequence (22 kilobases) of murine coronavirus gene I encoding the putative proteases and RNA polymerase Plus and minus strand leader RNAs in negative strand virus-infected cells Ribonucleoprotein-like structures from coronavirus particles RNA-binding domain of MHV N protein 159 Analysis of efficiently packaged defective interfering RNAs of murine coronavirus: localization of a possible packaging signal Molecular cloning: a laboratory manual Resolution of multiple complexes of phosphoprotein NS with nucleocapsid protein N of vesicular stomatitis virus Complex formation with vesicular stomatitis virus phosphoprotein NS prevents binding of nucleocapsid protein N to nonspecific RNA Structure and function studies of the nucleocapsid protein of mouse hepatitis virus Efficient in vitro synthesis of biological active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter Molecular cloning of the gene encoding the putative polymerase of mouse hepatitis coronavirus, strain A59 Sequence comparison of the N genes of five strains of the coronavirus mouse hepatitis virus suggests a three domain structure for the nucleocapsid protein A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein RNA-binding proteins of coronavirus MHV: detection of monomeric and multimeric N protein with an RNA overlay-protein blot assay The 54-kD protein of signal recognition particle contains a methionine-rich RNA binding domain DNA sequencing with chain terminating inhibitors Identification and primary structure of the gene encoding the Berne virus nucleocapsid protein Coronaviruses: structure and genome expression Assembly of nucleocapsidlike struct~es in animal cells infected with a vaccinia virus recombinant encoding the measles virus nucleoprorein Expression of a recombinant DNA gene coding for the vesicular stomatitis virus nucleocapsid protein Deans ILl (1988) By contrast, internal deletions or truncations extending beyond these two limits effectively abolished RNA binding by N protein.


id: cord-348179-i8w7huke
author: Xue, Yong
title: Increased risk of hepatitis E virus infection in schizophrenia
date: 2012-10-07
extension: .txt
mime: text/plain
words: 3365
sentence: 159
flesch: 52
cache: cache/cord-348179-i8w7huke.txt
txt: txt/cord-348179-i8w7huke.txt
summary:
  Therefore, schizophrenia patients exhibited a higher risk of HEV infection than controls. T-cell levels and the increased risk of HEV infection in schizophrenia patients.


id: cord-349907-dwhyx97y
author: Noh, Ji Yeong
date: 2017-02-20
extension: .txt
mime: text/plain
words: 3287
sentence: 108
flesch: 56
cache: cache/cord-349907-dwhyx97y.txt
txt: txt/cord-349907-dwhyx97y.txt
title:
  Simultaneous detection of severe acute respiratory syndrome, Middle East respiratory syndrome, and related bat coronaviruses by real-time reverse transcription PCR

summary:
  By testing the new method with bat samples as well as human samples, it could be applicable to survey SARS-CoV, MERS-CoV, and potentially their related bat CoVs in bats and human samples. It could successfully detect SARS-like CoV in bat samples but showed limited detection ability for the bat CoV HKU4 strain, which is related to MERS-CoV. However, according to a recent finding of EMC-like MERS-CoV, which was detected in bats of Saudi Arabia [18] , we assume that the new method can be helpful for screening for MERS-CoV in bat samples.


id: cord-348867-c0xpzd4d
author: Zhai, Jun-Qiong
title: First complete genome sequence of parainfluenza virus 5 isolated from lesser panda
date: 2017-01-30
extension: .txt
mime: text/plain
words: 1985
sentence: 69
flesch: 42
cache: cache/cord-348867-c0xpzd4d.txt
txt: txt/cord-348867-c0xpzd4d.txt
summary:
  Moreover, PIV5 nucleotide sequences were also detected in nasal swab samples from northeast tiger and south China tiger collected in 2016 in the same zoo, and their F genes were close to the lesser panda-origin PIV5 strain described here (data not shown). Measles, mumps, rubella, and human parvovirus B19 infections and neurologic disease Temporal, geographic, and host distribution of avian paramyxovirus 1 (Newcastle disease virus) Genome characterization and phylogenetic analysis of a lineage IV peste des petits ruminants virus in southern China Diversity of susceptible hosts in canine distemper virus infection: a systematic review and data synthesis New viral agents recovered from tissue cultures of monkey cells.


id: cord-329145-424vv8a8
author: Kuhn, Jens H.
date: 2012-09-23
extension: .txt
mime: text/plain
words: 5522
sentence: 193
flesch: 35
cache: cache/cord-329145-424vv8a8.txt
txt: txt/cord-329145-424vv8a8.txt
title:
  Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

summary:
  [30] by introducing virus names distinct from species names We suggest using the following medium-length designation for virus names in figures, such as phylograms, sequence alignments or diagrams: GenBank records are indexed with regard to taxonomy, and each record must be associated with the ''organism'' field.


id: cord-349964-38rgcc5h
author: Pedersen, N. C.
title: Antigenic relationship of the feline infectious peritonitis virus to coronaviruses of other species
date: 1978
extension: .txt
mime: text/plain
words: 3024
sentence: 136
flesch: 47
cache: cache/cord-349964-38rgcc5h.txt
txt: txt/cord-349964-38rgcc5h.txt
summary:
  Zbl Antigenic relationship between human corona virus strain 0C 43 and hemagglutinating encephalomyelitis virus strain 67N of swine: antibody responses in human and animal sera I~ecovery in tracheal organ cultures of novel viruses from patients with respiratory disease Antigenic relationship among the coronaviruses of man and between human and animal coronaviruses Detection of eoronavirus infection of man by immunofluorescence Seroepidemiology of feline infectious peritonitis virus infections using transmissible gastroenteritis virus as antigen Rat corona virus (RCV) : a prevalent, naturally occurring pneumotropic virus of rats Serologic studies of naturally occurring feline infectious peritonitis Morphologic and physical characteristics of feline infectious peritonitis virus and its growth in autochthonous peritoneal ceil cultures Feline infectious peritonitis: something old, something new Characteristics of a coronavirus causing vomition and wasting in pigs Detection of transmissible gastroenteritis virus neutralizing antibody in cats Characterization of a calf diarrheal coronavirus Characterization of a calf diarrheal coronavirus Morphology-of transmissible gastroenteritis virus of pigs Morphogenesis of a virus in cats with experimental feline infectious peritonitis Untersuchungen fiber die Antigenverwandtschaft der Viren der Felinen infekti6ser Peritonitis und der transmissiblen Gastroenteritis des Sehweines Ultrastruetural evidence for the viral etiology of feline infectious peritonitis Received October 23, 1977 A possible antigenic relationship between feline infectious peritonitis virus (FIPV) and the transmissible gastroenteritis virus (TGEV) of swine has been recently reported (13, 19, 25) , which further supports the assumption t h a t


id: cord-353797-yb355mxk
author: Inaba, Y.
title: Replication of bovine coronavirus in cell line BEK-1 culture
date: 1976
extension: .txt
mime: text/plain
words: 836
sentence: 30
flesch: 44
cache: cache/cord-353797-yb355mxk.txt
txt: txt/cord-353797-yb355mxk.txt
summary:
  The bovine corona~drus (3), at the 29th passage level in bovine embryonic kidney cells, was kindly supplied by Dr. C. A. Mebus, University of Nebraska, and was passaged twice in primary calf kidney cell cultures in our laboratory before use in the present study. The agent multiplied but failed to induce readily recognizable cytopathic effect in bovine embryonic kidney cell cultures (3) .


id: cord-342568-3sj235rm
author: Bald-Blume, Niklas
date: 2017-02-11
extension: .txt
mime: text/plain
words: 5369
sentence: 226
flesch: 49
cache: cache/cord-342568-3sj235rm.txt
txt: txt/cord-342568-3sj235rm.txt
title:
  Development of a molecular assay for the general detection of tospoviruses and the distinction between tospoviral species

summary:
  The standard method for virus detection (ELISA) lacks this potential and is quite labor-and time-intensive as it only allows to test for one virus at a time. In this study a new method for plant virus diagnosis is described using the Luminex xTAG


id: cord-345856-ckm0ol20
author: Zhong, Qiong
title: Antiviral activity of Arbidol against Coxsackie virus B5 in vitro and in vivo
date: 2009-03-17
extension: .txt
mime: text/plain
words: 3805
sentence: 165
flesch: 54
cache: cache/cord-345856-ckm0ol20.txt
txt: txt/cord-345856-ckm0ol20.txt
summary:
  Semi-quantitative detection of viral RNA by RT-PCR RNA was extracted from both supernatants and cells after compound treatment and virus infection using Trizol reagent (Invitrogen). RNA was extracted from the supernatants and cells in each well of the plates that were treated with the compound after virus infection, using Trizol (Invitrogen) according to the manufacturer's protocol.


id: cord-345940-adg264vb
author: Wanitchang, Asawin
date: 2018-08-22
extension: .txt
mime: text/plain
words: 5062
sentence: 180
flesch: 45
cache: cache/cord-345940-adg264vb.txt
txt: txt/cord-345940-adg264vb.txt
title:
  Characterization of influenza A virus pseudotyped with the spike protein of porcine epidemic diarrhea virus

summary:
  The full-length PEDV S derived from PEDV AVCT12 (Gen-Bank LC053455.1), PEDV YN144 (GenBank KT021232.1) and PEDV G2 (field isolate) were codon-optimized for expression in mammalian cells and synthesized (Genscript and Synbio Tech). Because the construction of recombinant PEDV bearing specific mutations in the S gene can be technically challenging, the available data concerning the binding of PEDV S to sialic-acid-containing glycoproteins in the context of infection have so far been limited to the use of natural isolates such as the PEDV-UU strain [15] .


id: cord-356192-8b96rgqa
author: Xie, Qian
date: 2017-04-18
extension: .txt
mime: text/plain
words: 2430
sentence: 111
flesch: 48
cache: cache/cord-356192-8b96rgqa.txt
txt: txt/cord-356192-8b96rgqa.txt
title:
  Two deletion variants of Middle East respiratory syndrome coronavirus found in a patient with characteristic symptoms

summary:
  Protein sequences were aligned using MEGA (version 6.0) Even single point mutations in the transmembrane protein of the infectious bronchitis virus (IBV) E protein [23] , or amino acid changes in the N-terminus of the SARS-CoV E protein can result in attenuation of virulence [24] .


id: cord-348163-9q1rt8i7
author: Hussein, Hosni A. M.
title: Beyond RGD: virus interactions with integrins
date: 2015-09-01
extension: .txt
mime: text/plain
words: 5970
sentence: 229
flesch: 30
cache: cache/cord-348163-9q1rt8i7.txt
txt: txt/cord-348163-9q1rt8i7.txt
summary:
  The most common of these motifs is the minimal peptide sequence for binding integrins, RGD (Arg-Gly-Asp), which is known for its role in virus infection via its ability to interact with over half of the more than 20 known integrins. RGD is the minimal peptide sequence for binding integrins.


