id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
aiua-1760	Candiano, Giuseppe; Pepe, Pietro; Pietropaolo, Francesco; Aragona, Francesco	Does prolonged anti-inflammatory therapy reduce number of unnecessary repeat saturation prostate biopsy?	2013	4	.pdf	application/pdf	2841	153	56	The intra-individual (physiological) variation of PSA in men with benign prostate biopsy is equal to 9.5% (12); more- over, many common medications have an effect on serum PSA levels: NSAIDs, thiazide diuretics and statins reduce PSA levels from 6% to 26% and the combination of statins with thiazide diuretics could decrease PSA lev- MATERIAL AND METHODS From September 2011 to September 2012, 70 patients (median age 62 years; range: 49-72 years), with previous negative extended prostate biopsy and persistent abnor- mal PSA values, were given an herbal extract with anti- inflammatory activity (Lenidase®, 1 tablet daily) for 3 months. PSA levels have been correlated with the extent and degree of inflammation (2, 3) and a short trial of antibi- otics for a likely subclinical CP has some theoretical advantages in decreasing PSA levels (34.6-56% of the cases) (4, 5) thus minimizing the number of biopsies for falsely elevated PSA (20-30% of the cases) (6, 7).	cache/aiua-1760.pdf	txt/aiua-1760.txt