id	sid	tid	token	lemma	pos
aiua-11292	1	1	stesura	stesura	PROPN
aiua-11292	1	2	seveso	seveso	PROPN
aiua-11292	1	3	archivio	archivio	PROPN
aiua-11292	1	4	italiano	italiano	X
aiua-11292	1	5	di	di	X
aiua-11292	1	6	urologia	urologia	PROPN
aiua-11292	1	7	e	e	PROPN
aiua-11292	1	8	andrologia	andrologia	NOUN
aiua-11292	1	9	2023	2023	NUM
aiua-11292	1	10	;	;	PUNCT
aiua-11292	1	11	95	95	NUM
aiua-11292	1	12	,	,	PUNCT
aiua-11292	1	13	2	2	NUM
aiua-11292	1	14	28	28	NUM
aiua-11292	1	15	original	original	ADJ
aiua-11292	1	16	paper	paper	NOUN
aiua-11292	1	17	factor	factor	NOUN
aiua-11292	1	18	for	for	ADP
aiua-11292	1	19	ubc	ubc	PROPN
aiua-11292	1	20	.	.	PROPN
aiua-11292	1	21	exposure	exposure	NOUN
aiua-11292	1	22	to	to	ADP
aiua-11292	1	23	chemical	chemical	ADJ
aiua-11292	1	24	compounds	compound	NOUN
aiua-11292	1	25	,	,	PUNCT
aiua-11292	1	26	particularly	particularly	ADV
aiua-11292	1	27	aromatic	aromatic	ADJ
aiua-11292	1	28	amines	amine	NOUN
aiua-11292	1	29	and	and	CCONJ
aiua-11292	1	30	polycyclic	polycyclic	NOUN
aiua-11292	1	31	aromatic	aromatic	ADJ
aiua-11292	1	32	hydrocarbons	hydrocarbon	NOUN
aiua-11292	1	33	,	,	PUNCT
aiua-11292	1	34	parasitic	parasitic	ADJ
aiua-11292	1	35	infection	infection	NOUN
aiua-11292	1	36	,	,	PUNCT
aiua-11292	1	37	along	along	ADP
aiua-11292	1	38	with	with	ADP
aiua-11292	1	39	genetic	genetic	ADJ
aiua-11292	1	40	predisposition	predisposition	NOUN
aiua-11292	1	41	are	be	AUX
aiua-11292	1	42	also	also	ADV
aiua-11292	1	43	considerable	considerable	ADJ
aiua-11292	1	44	risk	risk	NOUN
aiua-11292	1	45	factors	factor	NOUN
aiua-11292	1	46	(	(	PUNCT
aiua-11292	1	47	1	1	NUM
aiua-11292	1	48	,	,	PUNCT
aiua-11292	1	49	4	4	NUM
aiua-11292	1	50	)	)	PUNCT
aiua-11292	1	51	.	.	PUNCT
aiua-11292	2	1	approximately	approximately	ADV
aiua-11292	2	2	25	25	NUM
aiua-11292	2	3	%	%	NOUN
aiua-11292	2	4	of	of	ADP
aiua-11292	2	5	newly	newly	ADV
aiua-11292	2	6	diagnosed	diagnose	VERB
aiua-11292	2	7	ubc	ubc	NOUN
aiua-11292	2	8	are	be	AUX
aiua-11292	2	9	invasive	invasive	ADJ
aiua-11292	2	10	,	,	PUNCT
aiua-11292	2	11	requiring	require	VERB
aiua-11292	2	12	radical	radical	ADJ
aiua-11292	2	13	surgery	surgery	NOUN
aiua-11292	2	14	or	or	CCONJ
aiua-11292	2	15	radiotherapy	radiotherapy	NOUN
aiua-11292	2	16	(	(	PUNCT
aiua-11292	2	17	1	1	NUM
aiua-11292	2	18	,	,	PUNCT
aiua-11292	2	19	2	2	NUM
aiua-11292	2	20	,	,	PUNCT
aiua-11292	2	21	5	5	NUM
aiua-11292	2	22	)	)	PUNCT
aiua-11292	2	23	.	.	PUNCT
aiua-11292	3	1	unfortunately	unfortunately	ADV
aiua-11292	3	2	,	,	PUNCT
aiua-11292	3	3	the	the	DET
aiua-11292	3	4	disease	disease	NOUN
aiua-11292	3	5	outcome	outcome	NOUN
aiua-11292	3	6	is	be	AUX
aiua-11292	3	7	still	still	ADV
aiua-11292	3	8	poor	poor	ADJ
aiua-11292	3	9	despite	despite	SCONJ
aiua-11292	3	10	systemic	systemic	ADJ
aiua-11292	3	11	therapy	therapy	NOUN
aiua-11292	3	12	(	(	PUNCT
aiua-11292	3	13	1	1	NUM
aiua-11292	3	14	)	)	PUNCT
aiua-11292	3	15	.	.	PUNCT
aiua-11292	4	1	five	five	NUM
aiua-11292	4	2	-	-	PUNCT
aiua-11292	4	3	year	year	NOUN
aiua-11292	4	4	overall	overall	ADJ
aiua-11292	4	5	survival	survival	NOUN
aiua-11292	4	6	(	(	PUNCT
aiua-11292	4	7	os	os	NOUN
aiua-11292	4	8	)	)	PUNCT
aiua-11292	4	9	and	and	CCONJ
aiua-11292	4	10	disease	disease	NOUN
aiua-11292	4	11	-	-	PUNCT
aiua-11292	4	12	specific	specific	ADJ
aiua-11292	4	13	survival	survival	NOUN
aiua-11292	4	14	(	(	PUNCT
aiua-11292	4	15	dss	dss	NOUN
aiua-11292	4	16	)	)	PUNCT
aiua-11292	4	17	rates	rate	NOUN
aiua-11292	4	18	for	for	ADP
aiua-11292	4	19	ubc	ubc	PROPN
aiua-11292	4	20	are	be	AUX
aiua-11292	4	21	57.2	57.2	NUM
aiua-11292	4	22	%	%	NOUN
aiua-11292	4	23	and	and	CCONJ
aiua-11292	4	24	77.3	77.3	NUM
aiua-11292	4	25	%	%	NOUN
aiua-11292	4	26	,	,	PUNCT
aiua-11292	4	27	respectively	respectively	ADV
aiua-11292	4	28	(	(	PUNCT
aiua-11292	4	29	2	2	NUM
aiua-11292	4	30	)	)	PUNCT
aiua-11292	4	31	.	.	PUNCT
aiua-11292	5	1	early	early	ADJ
aiua-11292	5	2	detection	detection	NOUN
aiua-11292	5	3	of	of	ADP
aiua-11292	5	4	ubc	ubc	PROPN
aiua-11292	5	5	is	be	AUX
aiua-11292	5	6	important	important	ADJ
aiua-11292	5	7	to	to	PART
aiua-11292	5	8	improve	improve	VERB
aiua-11292	5	9	patient	patient	NOUN
aiua-11292	5	10	’s	’s	PART
aiua-11292	5	11	outcome	outcome	NOUN
aiua-11292	5	12	,	,	PUNCT
aiua-11292	5	13	since	since	SCONJ
aiua-11292	5	14	the	the	DET
aiua-11292	5	15	treatment	treatment	NOUN
aiua-11292	5	16	can	can	AUX
aiua-11292	5	17	be	be	AUX
aiua-11292	5	18	delivered	deliver	VERB
aiua-11292	5	19	aggresively	aggresively	ADV
aiua-11292	5	20	.	.	PUNCT
aiua-11292	6	1	hypoxia	hypoxia	NOUN
aiua-11292	6	2	inducible	inducible	ADJ
aiua-11292	6	3	factor	factor	NOUN
aiua-11292	6	4	(	(	PUNCT
aiua-11292	6	5	hif)-1α	hif)-1α	NOUN
aiua-11292	6	6	is	be	AUX
aiua-11292	6	7	a	a	DET
aiua-11292	6	8	regulatory	regulatory	ADJ
aiua-11292	6	9	protein	protein	NOUN
aiua-11292	6	10	produced	produce	VERB
aiua-11292	6	11	in	in	ADP
aiua-11292	6	12	hypoxic	hypoxic	ADJ
aiua-11292	6	13	microenvironment	microenvironment	NOUN
aiua-11292	6	14	that	that	PRON
aiua-11292	6	15	consists	consist	VERB
aiua-11292	6	16	of	of	ADP
aiua-11292	6	17	two	two	NUM
aiua-11292	6	18	subunits	subunit	NOUN
aiua-11292	6	19	.	.	PUNCT
aiua-11292	7	1	its	its	PRON
aiua-11292	7	2	expression	expression	NOUN
aiua-11292	7	3	is	be	AUX
aiua-11292	7	4	found	find	VERB
aiua-11292	7	5	in	in	ADP
aiua-11292	7	6	several	several	ADJ
aiua-11292	7	7	solid	solid	ADJ
aiua-11292	7	8	tumors	tumor	NOUN
aiua-11292	7	9	including	include	VERB
aiua-11292	7	10	ubc	ubc	PROPN
aiua-11292	7	11	,	,	PUNCT
aiua-11292	7	12	lung	lung	NOUN
aiua-11292	7	13	,	,	PUNCT
aiua-11292	7	14	breast	breast	NOUN
aiua-11292	7	15	,	,	PUNCT
aiua-11292	7	16	ovary	ovary	ADJ
aiua-11292	7	17	,	,	PUNCT
aiua-11292	7	18	prostate	prostate	NOUN
aiua-11292	7	19	,	,	PUNCT
aiua-11292	7	20	and	and	CCONJ
aiua-11292	7	21	kidney	kidney	NOUN
aiua-11292	7	22	cancers	cancer	NOUN
aiua-11292	7	23	.	.	PUNCT
aiua-11292	8	1	the	the	DET
aiua-11292	8	2	binding	binding	NOUN
aiua-11292	8	3	of	of	ADP
aiua-11292	8	4	hif-1α	hif-1α	NOUN
aiua-11292	8	5	with	with	ADP
aiua-11292	8	6	its	its	PRON
aiua-11292	8	7	receptor	receptor	NOUN
aiua-11292	8	8	initiates	initiate	VERB
aiua-11292	8	9	cell	cell	NOUN
aiua-11292	8	10	proliferation	proliferation	NOUN
aiua-11292	8	11	,	,	PUNCT
aiua-11292	8	12	migration	migration	NOUN
aiua-11292	8	13	,	,	PUNCT
aiua-11292	8	14	and	and	CCONJ
aiua-11292	8	15	invasion	invasion	NOUN
aiua-11292	8	16	in	in	ADP
aiua-11292	8	17	ubc	ubc	PROPN
aiua-11292	8	18	(	(	PUNCT
aiua-11292	8	19	3	3	NUM
aiua-11292	8	20	,	,	PUNCT
aiua-11292	8	21	6	6	NUM
aiua-11292	8	22	,	,	PUNCT
aiua-11292	8	23	7	7	NUM
aiua-11292	8	24	)	)	PUNCT
aiua-11292	8	25	.	.	PUNCT
aiua-11292	9	1	additionally	additionally	ADV
aiua-11292	9	2	,	,	PUNCT
aiua-11292	9	3	hif-1α	hif-1α	NOUN
aiua-11292	9	4	is	be	AUX
aiua-11292	9	5	also	also	ADV
aiua-11292	9	6	closely	closely	ADV
aiua-11292	9	7	related	relate	VERB
aiua-11292	9	8	to	to	ADP
aiua-11292	9	9	angiogenesis	angiogenesis	NOUN
aiua-11292	9	10	(	(	PUNCT
aiua-11292	9	11	3	3	NUM
aiua-11292	9	12	,	,	PUNCT
aiua-11292	9	13	7	7	NUM
aiua-11292	9	14	-	-	SYM
aiua-11292	9	15	9	9	NUM
aiua-11292	9	16	)	)	PUNCT
aiua-11292	9	17	.	.	PUNCT
aiua-11292	10	1	in	in	ADP
aiua-11292	10	2	this	this	DET
aiua-11292	10	3	study	study	NOUN
aiua-11292	10	4	,	,	PUNCT
aiua-11292	10	5	we	we	PRON
aiua-11292	10	6	aimed	aim	VERB
aiua-11292	10	7	to	to	PART
aiua-11292	10	8	evaluate	evaluate	VERB
aiua-11292	10	9	the	the	DET
aiua-11292	10	10	association	association	NOUN
aiua-11292	10	11	between	between	ADP
aiua-11292	10	12	hif-1α	hif-1α	NOUN
aiua-11292	10	13	and	and	CCONJ
aiua-11292	10	14	stage	stage	NOUN
aiua-11292	10	15	and	and	CCONJ
aiua-11292	10	16	grade	grade	NOUN
aiua-11292	10	17	of	of	ADP
aiua-11292	10	18	ubc	ubc	PROPN
aiua-11292	10	19	.	.	PUNCT
aiua-11292	11	1	our	our	PRON
aiua-11292	11	2	findings	finding	NOUN
aiua-11292	11	3	may	may	AUX
aiua-11292	11	4	provide	provide	VERB
aiua-11292	11	5	insight	insight	NOUN
aiua-11292	11	6	regarding	regard	VERB
aiua-11292	11	7	earlier	early	ADJ
aiua-11292	11	8	diagnosis	diagnosis	NOUN
aiua-11292	11	9	,	,	PUNCT
aiua-11292	11	10	prompt	prompt	ADJ
aiua-11292	11	11	management	management	NOUN
aiua-11292	11	12	,	,	PUNCT
aiua-11292	11	13	improved	improved	ADJ
aiua-11292	11	14	outcome	outcome	NOUN
aiua-11292	11	15	,	,	PUNCT
aiua-11292	11	16	and	and	CCONJ
aiua-11292	11	17	possible	possible	ADJ
aiua-11292	11	18	therapeutic	therapeutic	ADJ
aiua-11292	11	19	method	method	NOUN
aiua-11292	11	20	for	for	ADP
aiua-11292	11	21	ubc	ubc	PROPN
aiua-11292	11	22	.	.	PROPN
aiua-11292	11	23	methods	method	NOUN
aiua-11292	11	24	this	this	PRON
aiua-11292	11	25	was	be	AUX
aiua-11292	11	26	a	a	DET
aiua-11292	11	27	case	case	NOUN
aiua-11292	11	28	-	-	PUNCT
aiua-11292	11	29	control	control	NOUN
aiua-11292	11	30	study	study	NOUN
aiua-11292	11	31	conducted	conduct	VERB
aiua-11292	11	32	in	in	ADP
aiua-11292	11	33	januarydecember	januarydecember	NOUN
aiua-11292	11	34	2022	2022	NUM
aiua-11292	11	35	at	at	ADP
aiua-11292	11	36	haji	haji	PROPN
aiua-11292	11	37	adam	adam	PROPN
aiua-11292	11	38	malik	malik	PROPN
aiua-11292	11	39	hospital	hospital	PROPN
aiua-11292	11	40	medan	medan	PROPN
aiua-11292	11	41	,	,	PUNCT
aiua-11292	11	42	indonesia	indonesia	PROPN
aiua-11292	11	43	.	.	PUNCT
aiua-11292	12	1	the	the	DET
aiua-11292	12	2	inclusion	inclusion	NOUN
aiua-11292	12	3	criteria	criterion	NOUN
aiua-11292	12	4	for	for	ADP
aiua-11292	12	5	case	case	NOUN
aiua-11292	12	6	group	group	NOUN
aiua-11292	12	7	was	be	AUX
aiua-11292	12	8	subject	subject	ADJ
aiua-11292	12	9	aged	aged	ADJ
aiua-11292	12	10	18	18	NUM
aiua-11292	12	11	years	year	NOUN
aiua-11292	12	12	or	or	CCONJ
aiua-11292	12	13	older	old	ADJ
aiua-11292	12	14	and	and	CCONJ
aiua-11292	12	15	diagnosed	diagnose	VERB
aiua-11292	12	16	with	with	ADP
aiua-11292	12	17	ubc	ubc	PROPN
aiua-11292	12	18	based	base	VERB
aiua-11292	12	19	on	on	ADP
aiua-11292	12	20	histopathological	histopathological	ADJ
aiua-11292	12	21	examination	examination	NOUN
aiua-11292	12	22	.	.	PUNCT
aiua-11292	13	1	beside	beside	ADP
aiua-11292	13	2	diagnosing	diagnose	VERB
aiua-11292	13	3	ubc	ubc	PROPN
aiua-11292	13	4	,	,	PUNCT
aiua-11292	13	5	biopsy	biopsy	VERB
aiua-11292	13	6	specimen	speciman	NOUN
aiua-11292	13	7	from	from	ADP
aiua-11292	13	8	case	case	NOUN
aiua-11292	13	9	group	group	NOUN
aiua-11292	13	10	underwent	undergo	VERB
aiua-11292	13	11	hematoxylin	hematoxylin	NOUN
aiua-11292	13	12	and	and	CCONJ
aiua-11292	13	13	eosin	eosin	NOUN
aiua-11292	13	14	staining	stain	VERB
aiua-11292	13	15	to	to	PART
aiua-11292	13	16	determine	determine	VERB
aiua-11292	13	17	stage	stage	NOUN
aiua-11292	13	18	and	and	CCONJ
aiua-11292	13	19	grade	grade	NOUN
aiua-11292	13	20	of	of	ADP
aiua-11292	13	21	disease	disease	NOUN
aiua-11292	13	22	.	.	PUNCT
aiua-11292	14	1	all	all	DET
aiua-11292	14	2	histopathological	histopathological	ADJ
aiua-11292	14	3	examinations	examination	NOUN
aiua-11292	14	4	were	be	AUX
aiua-11292	14	5	conducted	conduct	VERB
aiua-11292	14	6	at	at	ADP
aiua-11292	14	7	department	department	NOUN
aiua-11292	14	8	of	of	ADP
aiua-11292	14	9	pathology	pathology	NOUN
aiua-11292	14	10	of	of	ADP
aiua-11292	14	11	universitas	universita	NOUN
aiua-11292	14	12	sumatera	sumatera	NOUN
aiua-11292	14	13	utara	utara	NOUN
aiua-11292	14	14	.	.	PUNCT
aiua-11292	15	1	control	control	PROPN
aiua-11292	15	2	group	group	PROPN
aiua-11292	15	3	included	include	VERB
aiua-11292	15	4	healthy	healthy	ADJ
aiua-11292	15	5	subjects	subject	NOUN
aiua-11292	15	6	who	who	PRON
aiua-11292	15	7	came	come	VERB
aiua-11292	15	8	to	to	ADP
aiua-11292	15	9	the	the	DET
aiua-11292	15	10	hospital	hospital	NOUN
aiua-11292	15	11	for	for	ADP
aiua-11292	15	12	general	general	ADJ
aiua-11292	15	13	check	check	NOUN
aiua-11292	15	14	-	-	PUNCT
aiua-11292	15	15	up	up	NOUN
aiua-11292	15	16	or	or	CCONJ
aiua-11292	15	17	healthy	healthy	ADJ
aiua-11292	15	18	hospital	hospital	NOUN
aiua-11292	15	19	employers	employer	NOUN
aiua-11292	15	20	.	.	PUNCT
aiua-11292	16	1	exclusion	exclusion	NOUN
aiua-11292	16	2	criteria	criterion	NOUN
aiua-11292	16	3	was	be	AUX
aiua-11292	16	4	previous	previous	ADJ
aiua-11292	16	5	history	history	NOUN
aiua-11292	16	6	of	of	ADP
aiua-11292	16	7	introduction	introduction	NOUN
aiua-11292	16	8	:	:	PUNCT
aiua-11292	16	9	we	we	PRON
aiua-11292	16	10	aim	aim	VERB
aiua-11292	16	11	to	to	PART
aiua-11292	16	12	evaluate	evaluate	VERB
aiua-11292	16	13	the	the	DET
aiua-11292	16	14	association	association	NOUN
aiua-11292	16	15	between	between	ADP
aiua-11292	16	16	serum	serum	NOUN
aiua-11292	16	17	hypoxia	hypoxia	NOUN
aiua-11292	16	18	inducible	inducible	ADJ
aiua-11292	16	19	factor	factor	NOUN
aiua-11292	16	20	(	(	PUNCT
aiua-11292	16	21	hif)-1α	hif)-1α	NOUN
aiua-11292	16	22	level	level	NOUN
aiua-11292	16	23	and	and	CCONJ
aiua-11292	16	24	stage	stage	NOUN
aiua-11292	16	25	and	and	CCONJ
aiua-11292	16	26	grade	grade	NOUN
aiua-11292	16	27	of	of	ADP
aiua-11292	16	28	urothelial	urothelial	ADJ
aiua-11292	16	29	bladder	bladder	NOUN
aiua-11292	16	30	cancer	cancer	NOUN
aiua-11292	16	31	(	(	PUNCT
aiua-11292	16	32	ubc	ubc	PROPN
aiua-11292	16	33	)	)	PUNCT
aiua-11292	16	34	.	.	PUNCT
aiua-11292	17	1	methods	method	NOUN
aiua-11292	17	2	:	:	PUNCT
aiua-11292	17	3	a	a	DET
aiua-11292	17	4	case	case	NOUN
aiua-11292	17	5	-	-	PUNCT
aiua-11292	17	6	control	control	NOUN
aiua-11292	17	7	study	study	NOUN
aiua-11292	17	8	was	be	AUX
aiua-11292	17	9	conducted	conduct	VERB
aiua-11292	17	10	at	at	ADP
aiua-11292	17	11	haji	haji	PROPN
aiua-11292	17	12	adam	adam	PROPN
aiua-11292	17	13	malik	malik	PROPN
aiua-11292	17	14	hospital	hospital	PROPN
aiua-11292	17	15	medan	medan	PROPN
aiua-11292	17	16	,	,	PUNCT
aiua-11292	17	17	indonesia	indonesia	PROPN
aiua-11292	17	18	.	.	PUNCT
aiua-11292	18	1	inclusion	inclusion	NOUN
aiua-11292	18	2	criteria	criterion	NOUN
aiua-11292	18	3	for	for	ADP
aiua-11292	18	4	case	case	NOUN
aiua-11292	18	5	group	group	NOUN
aiua-11292	18	6	was	be	AUX
aiua-11292	18	7	subject	subject	ADJ
aiua-11292	18	8	aged	aged	ADJ
aiua-11292	18	9	18	18	NUM
aiua-11292	18	10	years	year	NOUN
aiua-11292	18	11	or	or	CCONJ
aiua-11292	18	12	older	old	ADJ
aiua-11292	18	13	and	and	CCONJ
aiua-11292	18	14	diagnosed	diagnose	VERB
aiua-11292	18	15	with	with	ADP
aiua-11292	18	16	ubc	ubc	PROPN
aiua-11292	18	17	based	base	VERB
aiua-11292	18	18	on	on	ADP
aiua-11292	18	19	histopathological	histopathological	ADJ
aiua-11292	18	20	examination	examination	NOUN
aiua-11292	18	21	.	.	PUNCT
aiua-11292	19	1	control	control	PROPN
aiua-11292	19	2	group	group	PROPN
aiua-11292	19	3	consisted	consist	VERB
aiua-11292	19	4	of	of	ADP
aiua-11292	19	5	gender	gender	NOUN
aiua-11292	19	6	and	and	CCONJ
aiua-11292	19	7	age	age	NOUN
aiua-11292	19	8	matched	match	VERB
aiua-11292	19	9	healthy	healthy	ADJ
aiua-11292	19	10	subjects	subject	NOUN
aiua-11292	19	11	.	.	PUNCT
aiua-11292	20	1	serum	serum	NOUN
aiua-11292	20	2	hif-1α	hif-1α	NOUN
aiua-11292	20	3	level	level	NOUN
aiua-11292	20	4	was	be	AUX
aiua-11292	20	5	determined	determine	VERB
aiua-11292	20	6	using	use	VERB
aiua-11292	20	7	elisa	elisa	NOUN
aiua-11292	20	8	method	method	NOUN
aiua-11292	20	9	.	.	PUNCT
aiua-11292	21	1	data	datum	NOUN
aiua-11292	21	2	was	be	AUX
aiua-11292	21	3	analyzed	analyze	VERB
aiua-11292	21	4	with	with	ADP
aiua-11292	21	5	chi	chi	PROPN
aiua-11292	21	6	square	square	PROPN
aiua-11292	21	7	,	,	PUNCT
aiua-11292	21	8	mann	mann	PROPN
aiua-11292	21	9	whitney	whitney	PROPN
aiua-11292	21	10	,	,	PUNCT
aiua-11292	21	11	and	and	CCONJ
aiua-11292	21	12	independent	independent	ADJ
aiua-11292	21	13	t	t	NOUN
aiua-11292	21	14	tests	test	NOUN
aiua-11292	21	15	.	.	PUNCT
aiua-11292	22	1	results	result	NOUN
aiua-11292	22	2	:	:	PUNCT
aiua-11292	22	3	a	a	DET
aiua-11292	22	4	total	total	NOUN
aiua-11292	22	5	of	of	ADP
aiua-11292	22	6	80	80	NUM
aiua-11292	22	7	subjects	subject	NOUN
aiua-11292	22	8	were	be	AUX
aiua-11292	22	9	enrolled	enrol	VERB
aiua-11292	22	10	and	and	CCONJ
aiua-11292	22	11	divided	divide	VERB
aiua-11292	22	12	into	into	ADP
aiua-11292	22	13	case	case	NOUN
aiua-11292	22	14	and	and	CCONJ
aiua-11292	22	15	control	control	NOUN
aiua-11292	22	16	groups	group	NOUN
aiua-11292	22	17	equally	equally	ADV
aiua-11292	22	18	.	.	PUNCT
aiua-11292	23	1	most	most	ADJ
aiua-11292	23	2	subjects	subject	NOUN
aiua-11292	23	3	were	be	AUX
aiua-11292	23	4	males	male	NOUN
aiua-11292	23	5	with	with	ADP
aiua-11292	23	6	mean	mean	ADJ
aiua-11292	23	7	age	age	NOUN
aiua-11292	23	8	of	of	ADP
aiua-11292	23	9	69.65	69.65	NUM
aiua-11292	23	10	years	year	NOUN
aiua-11292	23	11	for	for	ADP
aiua-11292	23	12	case	case	NOUN
aiua-11292	23	13	group	group	NOUN
aiua-11292	23	14	and	and	CCONJ
aiua-11292	23	15	68.25	68.25	NUM
aiua-11292	23	16	years	year	NOUN
aiua-11292	23	17	for	for	ADP
aiua-11292	23	18	control	control	NOUN
aiua-11292	23	19	group	group	NOUN
aiua-11292	23	20	.	.	PUNCT
aiua-11292	24	1	most	most	ADJ
aiua-11292	24	2	subjects	subject	NOUN
aiua-11292	24	3	had	have	VERB
aiua-11292	24	4	advanced	advanced	ADJ
aiua-11292	24	5	primary	primary	ADJ
aiua-11292	24	6	tumor	tumor	NOUN
aiua-11292	24	7	and	and	CCONJ
aiua-11292	24	8	lymph	lymph	NOUN
aiua-11292	24	9	node	node	ADJ
aiua-11292	24	10	stages	stage	NOUN
aiua-11292	24	11	.	.	PUNCT
aiua-11292	25	1	only	only	ADV
aiua-11292	25	2	30	30	NUM
aiua-11292	25	3	%	%	NOUN
aiua-11292	25	4	subjects	subject	NOUN
aiua-11292	25	5	had	have	AUX
aiua-11292	25	6	metastasized	metastasize	VERB
aiua-11292	25	7	ubc	ubc	PROPN
aiua-11292	25	8	.	.	PROPN
aiua-11292	26	1	higher	high	ADJ
aiua-11292	26	2	serum	serum	NOUN
aiua-11292	26	3	hif-1α	hif-1α	NOUN
aiua-11292	26	4	level	level	NOUN
aiua-11292	26	5	was	be	AUX
aiua-11292	26	6	observed	observe	VERB
aiua-11292	26	7	in	in	ADP
aiua-11292	26	8	case	case	NOUN
aiua-11292	26	9	group	group	NOUN
aiua-11292	26	10	(	(	PUNCT
aiua-11292	26	11	p	p	X
aiua-11292	26	12	<	<	X
aiua-11292	26	13	0.001	0.001	NUM
aiua-11292	26	14	)	)	PUNCT
aiua-11292	26	15	.	.	PUNCT
aiua-11292	27	1	serum	serum	PROPN
aiua-11292	27	2	hif-1α	hif-1α	PROPN
aiua-11292	27	3	level	level	NOUN
aiua-11292	27	4	was	be	AUX
aiua-11292	27	5	strongly	strongly	ADV
aiua-11292	27	6	associated	associate	VERB
aiua-11292	27	7	with	with	ADP
aiua-11292	27	8	metastasis	metastasis	NOUN
aiua-11292	27	9	stage	stage	NOUN
aiua-11292	27	10	(	(	PUNCT
aiua-11292	27	11	p	p	X
aiua-11292	27	12	<	<	X
aiua-11292	27	13	0.001	0.001	NUM
aiua-11292	27	14	)	)	PUNCT
aiua-11292	27	15	,	,	PUNCT
aiua-11292	27	16	followed	follow	VERB
aiua-11292	27	17	by	by	ADP
aiua-11292	27	18	lymph	lymph	NOUN
aiua-11292	27	19	node	node	NOUN
aiua-11292	27	20	(	(	PUNCT
aiua-11292	27	21	p	p	NOUN
aiua-11292	27	22	=	=	NOUN
aiua-11292	27	23	0.005	0.005	NUM
aiua-11292	27	24	)	)	PUNCT
aiua-11292	27	25	and	and	CCONJ
aiua-11292	27	26	primary	primary	ADJ
aiua-11292	27	27	tumor	tumor	NOUN
aiua-11292	27	28	(	(	PUNCT
aiua-11292	27	29	p	p	NOUN
aiua-11292	27	30	=	=	NOUN
aiua-11292	27	31	0	0	NUM
aiua-11292	27	32	.	.	NOUN
aiua-11292	27	33	013	013	NUM
aiua-11292	27	34	)	)	PUNCT
aiua-11292	27	35	stages	stage	NOUN
aiua-11292	27	36	.	.	PUNCT
aiua-11292	28	1	serum	serum	NOUN
aiua-11292	28	2	hif-1α	hif-1α	PROPN
aiua-11292	28	3	level	level	NOUN
aiua-11292	28	4	was	be	AUX
aiua-11292	28	5	not	not	PART
aiua-11292	28	6	associated	associate	VERB
aiua-11292	28	7	with	with	ADP
aiua-11292	28	8	grading	grade	VERB
aiua-11292	28	9	(	(	PUNCT
aiua-11292	28	10	p	p	X
aiua-11292	28	11	=	=	NOUN
aiua-11292	28	12	0.134	0.134	NUM
aiua-11292	28	13	)	)	PUNCT
aiua-11292	28	14	.	.	PUNCT
aiua-11292	29	1	conclusions	conclusion	NOUN
aiua-11292	29	2	:	:	PUNCT
aiua-11292	29	3	serum	serum	NOUN
aiua-11292	29	4	hif-1α	hif-1α	NOUN
aiua-11292	29	5	level	level	NOUN
aiua-11292	29	6	is	be	AUX
aiua-11292	29	7	associated	associate	VERB
aiua-11292	29	8	with	with	ADP
aiua-11292	29	9	staging	staging	NOUN
aiua-11292	29	10	but	but	CCONJ
aiua-11292	29	11	not	not	PART
aiua-11292	29	12	grading	grade	VERB
aiua-11292	29	13	of	of	ADP
aiua-11292	29	14	ubc	ubc	PROPN
aiua-11292	29	15	.	.	PUNCT
aiua-11292	30	1	key	key	ADJ
aiua-11292	30	2	words	word	NOUN
aiua-11292	30	3	:	:	PUNCT
aiua-11292	30	4	hif-1α	hif-1α	NOUN
aiua-11292	30	5	;	;	PUNCT
aiua-11292	30	6	grade	grade	NOUN
aiua-11292	30	7	;	;	PUNCT
aiua-11292	30	8	stage	stage	NOUN
aiua-11292	30	9	;	;	PUNCT
aiua-11292	30	10	urothelial	urothelial	ADJ
aiua-11292	30	11	bladder	bladder	NOUN
aiua-11292	30	12	cancer	cancer	NOUN
aiua-11292	30	13	.	.	PUNCT
aiua-11292	30	14	submitted	submit	VERB
aiua-11292	30	15	5	5	NUM
aiua-11292	30	16	march	march	NOUN
aiua-11292	30	17	2023	2023	NUM
aiua-11292	30	18	;	;	PUNCT
aiua-11292	30	19	accepted	accept	VERB
aiua-11292	30	20	2	2	NUM
aiua-11292	30	21	april	april	PROPN
aiua-11292	30	22	2023	2023	NUM
aiua-11292	30	23	introduction	introduction	NOUN
aiua-11292	30	24	urothelial	urothelial	ADJ
aiua-11292	30	25	bladder	bladder	NOUN
aiua-11292	30	26	cancer	cancer	NOUN
aiua-11292	30	27	(	(	PUNCT
aiua-11292	30	28	ubc	ubc	PROPN
aiua-11292	30	29	)	)	PUNCT
aiua-11292	30	30	is	be	AUX
aiua-11292	30	31	the	the	DET
aiua-11292	30	32	7th	7th	ADJ
aiua-11292	30	33	and	and	CCONJ
aiua-11292	30	34	the	the	DET
aiua-11292	30	35	17th	17th	ADJ
aiua-11292	30	36	most	most	ADV
aiua-11292	30	37	common	common	ADJ
aiua-11292	30	38	cancer	cancer	NOUN
aiua-11292	30	39	globally	globally	ADV
aiua-11292	30	40	in	in	ADP
aiua-11292	30	41	men	man	NOUN
aiua-11292	30	42	and	and	CCONJ
aiua-11292	30	43	women	woman	NOUN
aiua-11292	30	44	,	,	PUNCT
aiua-11292	30	45	respectively	respectively	ADV
aiua-11292	30	46	(	(	PUNCT
aiua-11292	30	47	1	1	NUM
aiua-11292	30	48	)	)	PUNCT
aiua-11292	30	49	.	.	PUNCT
aiua-11292	31	1	this	this	DET
aiua-11292	31	2	subtype	subtype	NOUN
aiua-11292	31	3	is	be	AUX
aiua-11292	31	4	responsible	responsible	ADJ
aiua-11292	31	5	for	for	ADP
aiua-11292	31	6	more	more	ADJ
aiua-11292	31	7	than	than	ADP
aiua-11292	31	8	90	90	NUM
aiua-11292	31	9	%	%	NOUN
aiua-11292	31	10	bladder	bladder	NOUN
aiua-11292	31	11	cancer	cancer	NOUN
aiua-11292	31	12	cases	case	NOUN
aiua-11292	31	13	(	(	PUNCT
aiua-11292	31	14	2	2	NUM
aiua-11292	31	15	,	,	PUNCT
aiua-11292	31	16	3	3	NUM
aiua-11292	31	17	)	)	PUNCT
aiua-11292	31	18	.	.	PUNCT
aiua-11292	32	1	annually	annually	ADV
aiua-11292	32	2	,	,	PUNCT
aiua-11292	32	3	there	there	PRON
aiua-11292	32	4	are	be	VERB
aiua-11292	32	5	110.500	110.500	NUM
aiua-11292	32	6	men	man	NOUN
aiua-11292	32	7	and	and	CCONJ
aiua-11292	32	8	70.000	70.000	NUM
aiua-11292	32	9	women	woman	NOUN
aiua-11292	32	10	diagnosed	diagnose	VERB
aiua-11292	32	11	with	with	ADP
aiua-11292	32	12	new	new	PROPN
aiua-11292	32	13	ubc	ubc	PROPN
aiua-11292	32	14	cases	case	NOUN
aiua-11292	32	15	worldwide	worldwide	ADV
aiua-11292	32	16	.	.	PUNCT
aiua-11292	33	1	the	the	DET
aiua-11292	33	2	disease	disease	NOUN
aiua-11292	33	3	is	be	AUX
aiua-11292	33	4	more	more	ADV
aiua-11292	33	5	frequent	frequent	ADJ
aiua-11292	33	6	in	in	ADP
aiua-11292	33	7	developed	develop	VERB
aiua-11292	33	8	countries	country	NOUN
aiua-11292	33	9	(	(	PUNCT
aiua-11292	33	10	1	1	NUM
aiua-11292	33	11	)	)	PUNCT
aiua-11292	33	12	.	.	PUNCT
aiua-11292	34	1	every	every	DET
aiua-11292	34	2	year	year	NOUN
aiua-11292	34	3	,	,	PUNCT
aiua-11292	34	4	38.200	38.200	NUM
aiua-11292	34	5	cases	case	NOUN
aiua-11292	34	6	were	be	AUX
aiua-11292	34	7	diagnosed	diagnose	VERB
aiua-11292	34	8	in	in	ADP
aiua-11292	34	9	european	european	PROPN
aiua-11292	34	10	union	union	PROPN
aiua-11292	34	11	and	and	CCONJ
aiua-11292	34	12	17.000	17.000	NUM
aiua-11292	34	13	subjects	subject	NOUN
aiua-11292	34	14	died	die	VERB
aiua-11292	34	15	due	due	ADJ
aiua-11292	34	16	to	to	ADP
aiua-11292	34	17	ubc	ubc	PROPN
aiua-11292	34	18	(	(	PUNCT
aiua-11292	34	19	1	1	NUM
aiua-11292	34	20	,	,	PUNCT
aiua-11292	34	21	2	2	NUM
aiua-11292	34	22	)	)	PUNCT
aiua-11292	34	23	.	.	PUNCT
aiua-11292	35	1	smoking	smoking	NOUN
aiua-11292	35	2	is	be	AUX
aiua-11292	35	3	the	the	DET
aiua-11292	35	4	most	most	ADV
aiua-11292	35	5	important	important	ADJ
aiua-11292	35	6	risk	risk	NOUN
aiua-11292	35	7	the	the	DET
aiua-11292	35	8	association	association	NOUN
aiua-11292	35	9	between	between	ADP
aiua-11292	35	10	serum	serum	NOUN
aiua-11292	35	11	hypoxia	hypoxia	NOUN
aiua-11292	35	12	inducible	inducible	ADJ
aiua-11292	35	13	factor-1α	factor-1α	NOUN
aiua-11292	35	14	level	level	NOUN
aiua-11292	35	15	and	and	CCONJ
aiua-11292	35	16	urothelial	urothelial	ADJ
aiua-11292	35	17	bladder	bladder	NOUN
aiua-11292	35	18	cancer	cancer	NOUN
aiua-11292	35	19	:	:	PUNCT
aiua-11292	35	20	a	a	DET
aiua-11292	35	21	preliminary	preliminary	ADJ
aiua-11292	35	22	study	study	NOUN
aiua-11292	35	23	ginanda	ginanda	PROPN
aiua-11292	35	24	putra	putra	PROPN
aiua-11292	35	25	siregar	siregar	VERB
aiua-11292	35	26	1	1	NUM
aiua-11292	35	27	,	,	PUNCT
aiua-11292	35	28	2	2	NUM
aiua-11292	35	29	*	*	PUNCT
aiua-11292	35	30	,	,	PUNCT
aiua-11292	35	31	ida	ida	PROPN
aiua-11292	35	32	parwati	parwati	VERB
aiua-11292	35	33	3	3	NUM
aiua-11292	35	34	*	*	PROPN
aiua-11292	35	35	,	,	PUNCT
aiua-11292	35	36	bambang	bambang	PROPN
aiua-11292	35	37	sasongko	sasongko	VERB
aiua-11292	35	38	noegroho	noegroho	ADV
aiua-11292	35	39	4	4	NUM
aiua-11292	35	40	*	*	PUNCT
aiua-11292	35	41	,	,	PUNCT
aiua-11292	35	42	ferry	ferry	NOUN
aiua-11292	35	43	safridai	safridai	NOUN
aiua-11292	35	44	4	4	NUM
aiua-11292	35	45	*	*	NOUN
aiua-11292	35	46	,	,	PUNCT
aiua-11292	35	47	gerhard	gerhard	PROPN
aiua-11292	35	48	reinaldi	reinaldi	PROPN
aiua-11292	35	49	situmorang	situmorang	PROPN
aiua-11292	35	50	5	5	NUM
aiua-11292	35	51	,	,	PUNCT
aiua-11292	35	52	raden	raden	VERB
aiua-11292	35	53	yohana	yohana	PROPN
aiua-11292	35	54	6	6	NUM
aiua-11292	35	55	,	,	PUNCT
aiua-11292	35	56	astrid	astrid	PROPN
aiua-11292	35	57	feinisa	feinisa	PROPN
aiua-11292	35	58	khairani	khairani	VERB
aiua-11292	35	59	7	7	NUM
aiua-11292	35	60	1	1	NUM
aiua-11292	35	61	doctoral	doctoral	ADJ
aiua-11292	35	62	study	study	NOUN
aiua-11292	35	63	program	program	NOUN
aiua-11292	35	64	,	,	PUNCT
aiua-11292	35	65	faculty	faculty	NOUN
aiua-11292	35	66	of	of	ADP
aiua-11292	35	67	medicine	medicine	NOUN
aiua-11292	35	68	,	,	PUNCT
aiua-11292	35	69	universitas	universita	NOUN
aiua-11292	35	70	padjadjaran	padjadjaran	NOUN
aiua-11292	35	71	,	,	PUNCT
aiua-11292	35	72	bandung	bandung	PROPN
aiua-11292	35	73	,	,	PUNCT
aiua-11292	35	74	indonesia	indonesia	PROPN
aiua-11292	35	75	;	;	PUNCT
aiua-11292	35	76	2	2	NUM
aiua-11292	35	77	division	division	NOUN
aiua-11292	35	78	of	of	ADP
aiua-11292	35	79	urology	urology	NOUN
aiua-11292	35	80	,	,	PUNCT
aiua-11292	35	81	department	department	NOUN
aiua-11292	35	82	of	of	ADP
aiua-11292	35	83	surgery	surgery	NOUN
aiua-11292	35	84	,	,	PUNCT
aiua-11292	35	85	faculty	faculty	NOUN
aiua-11292	35	86	of	of	ADP
aiua-11292	35	87	medicine	medicine	NOUN
aiua-11292	35	88	,	,	PUNCT
aiua-11292	35	89	universitas	universita	NOUN
aiua-11292	35	90	sumatera	sumatera	NOUN
aiua-11292	35	91	utara	utara	NOUN
aiua-11292	35	92	,	,	PUNCT
aiua-11292	35	93	medan	medan	PROPN
aiua-11292	35	94	,	,	PUNCT
aiua-11292	35	95	indonesia	indonesia	PROPN
aiua-11292	35	96	;	;	PUNCT
aiua-11292	35	97	3	3	NUM
aiua-11292	35	98	department	department	NOUN
aiua-11292	35	99	of	of	ADP
aiua-11292	35	100	clinical	clinical	ADJ
aiua-11292	35	101	pathology	pathology	NOUN
aiua-11292	35	102	,	,	PUNCT
aiua-11292	35	103	faculty	faculty	NOUN
aiua-11292	35	104	of	of	ADP
aiua-11292	35	105	medicine	medicine	NOUN
aiua-11292	35	106	,	,	PUNCT
aiua-11292	35	107	universitas	universita	NOUN
aiua-11292	35	108	padjadjaran	padjadjaran	NOUN
aiua-11292	35	109	,	,	PUNCT
aiua-11292	35	110	bandung	bandung	PROPN
aiua-11292	35	111	,	,	PUNCT
aiua-11292	35	112	indonesia	indonesia	PROPN
aiua-11292	35	113	;	;	PUNCT
aiua-11292	35	114	4	4	NUM
aiua-11292	35	115	department	department	NOUN
aiua-11292	35	116	of	of	ADP
aiua-11292	35	117	urology	urology	NOUN
aiua-11292	35	118	,	,	PUNCT
aiua-11292	35	119	faculty	faculty	NOUN
aiua-11292	35	120	of	of	ADP
aiua-11292	35	121	medicine	medicine	NOUN
aiua-11292	35	122	,	,	PUNCT
aiua-11292	35	123	universitas	universita	NOUN
aiua-11292	35	124	padjadjaran	padjadjaran	NOUN
aiua-11292	35	125	,	,	PUNCT
aiua-11292	35	126	bandung	bandung	PROPN
aiua-11292	35	127	,	,	PUNCT
aiua-11292	35	128	indonesia	indonesia	PROPN
aiua-11292	35	129	;	;	PUNCT
aiua-11292	35	130	5	5	NUM
aiua-11292	35	131	department	department	NOUN
aiua-11292	35	132	of	of	ADP
aiua-11292	35	133	urology	urology	NOUN
aiua-11292	35	134	,	,	PUNCT
aiua-11292	35	135	faculty	faculty	NOUN
aiua-11292	35	136	of	of	ADP
aiua-11292	35	137	medicine	medicine	NOUN
aiua-11292	35	138	,	,	PUNCT
aiua-11292	35	139	universitas	universitas	PROPN
aiua-11292	35	140	indonesia	indonesia	PROPN
aiua-11292	35	141	,	,	PUNCT
aiua-11292	35	142	jakarta	jakarta	PROPN
aiua-11292	35	143	,	,	PUNCT
aiua-11292	35	144	indonesia	indonesia	PROPN
aiua-11292	35	145	;	;	PUNCT
aiua-11292	35	146	6	6	NUM
aiua-11292	35	147	division	division	NOUN
aiua-11292	35	148	of	of	ADP
aiua-11292	35	149	oncology	oncology	NOUN
aiua-11292	35	150	,	,	PUNCT
aiua-11292	35	151	department	department	NOUN
aiua-11292	35	152	of	of	ADP
aiua-11292	35	153	surgery	surgery	NOUN
aiua-11292	35	154	,	,	PUNCT
aiua-11292	35	155	faculty	faculty	NOUN
aiua-11292	35	156	of	of	ADP
aiua-11292	35	157	medicine	medicine	NOUN
aiua-11292	35	158	,	,	PUNCT
aiua-11292	35	159	padjadjaran	padjadjaran	NOUN
aiua-11292	35	160	university	university	PROPN
aiua-11292	35	161	,	,	PUNCT
aiua-11292	35	162	bandung	bandung	PROPN
aiua-11292	35	163	,	,	PUNCT
aiua-11292	35	164	indonesia	indonesia	PROPN
aiua-11292	35	165	;	;	PUNCT
aiua-11292	35	166	7	7	NUM
aiua-11292	35	167	department	department	NOUN
aiua-11292	35	168	of	of	ADP
aiua-11292	35	169	biomedical	biomedical	ADJ
aiua-11292	35	170	sciences	science	NOUN
aiua-11292	35	171	,	,	PUNCT
aiua-11292	35	172	faculty	faculty	NOUN
aiua-11292	35	173	of	of	ADP
aiua-11292	35	174	medicine	medicine	NOUN
aiua-11292	35	175	,	,	PUNCT
aiua-11292	35	176	universitas	universita	NOUN
aiua-11292	35	177	padjadjaran	padjadjaran	NOUN
aiua-11292	35	178	,	,	PUNCT
aiua-11292	35	179	bandung	bandung	PROPN
aiua-11292	35	180	,	,	PUNCT
aiua-11292	35	181	indonesia	indonesia	PROPN
aiua-11292	35	182	.	.	PUNCT
aiua-11292	36	1	*	*	PUNCT
aiua-11292	36	2	these	these	DET
aiua-11292	36	3	authors	author	NOUN
aiua-11292	36	4	contributed	contribute	VERB
aiua-11292	36	5	equally	equally	ADV
aiua-11292	36	6	to	to	ADP
aiua-11292	36	7	this	this	DET
aiua-11292	36	8	paper	paper	NOUN
aiua-11292	36	9	.	.	PUNCT
aiua-11292	37	1	doi	doi	NOUN
aiua-11292	37	2	:	:	PUNCT
aiua-11292	37	3	10.4081	10.4081	NUM
aiua-11292	37	4	/	/	SYM
aiua-11292	37	5	aiua.2023.11292	aiua.2023.11292	PRON
aiua-11292	37	6	summary	summary	VERB
aiua-11292	37	7	archivio	archivio	NOUN
aiua-11292	37	8	italiano	italiano	NOUN
aiua-11292	37	9	di	di	X
aiua-11292	37	10	urologia	urologia	PROPN
aiua-11292	37	11	e	e	PROPN
aiua-11292	37	12	andrologia	andrologia	NOUN
aiua-11292	37	13	2023	2023	NUM
aiua-11292	37	14	;	;	PUNCT
aiua-11292	37	15	95	95	NUM
aiua-11292	37	16	,	,	PUNCT
aiua-11292	37	17	2	2	NUM
aiua-11292	37	18	g.	g.	PROPN
aiua-11292	37	19	putra	putra	PROPN
aiua-11292	37	20	siregar	siregar	NOUN
aiua-11292	37	21	,	,	PUNCT
aiua-11292	37	22	ida	ida	PROPN
aiua-11292	37	23	parwati	parwati	PROPN
aiua-11292	37	24	,	,	PUNCT
aiua-11292	37	25	b.	b.	PROPN
aiua-11292	37	26	sasongko	sasongko	PROPN
aiua-11292	37	27	noegroho	noegroho	PROPN
aiua-11292	37	28	,	,	PUNCT
aiua-11292	37	29	et	et	PROPN
aiua-11292	37	30	al	al	PROPN
aiua-11292	37	31	.	.	PROPN
aiua-11292	37	32	29	29	NUM
aiua-11292	37	33	malignancy	malignancy	NOUN
aiua-11292	37	34	,	,	PUNCT
aiua-11292	37	35	bladder	bladder	NOUN
aiua-11292	37	36	lesion	lesion	NOUN
aiua-11292	37	37	due	due	ADJ
aiua-11292	37	38	to	to	ADP
aiua-11292	37	39	methastasis	methastasis	NOUN
aiua-11292	37	40	from	from	ADP
aiua-11292	37	41	distant	distant	ADJ
aiua-11292	37	42	primary	primary	ADJ
aiua-11292	37	43	cancers	cancer	NOUN
aiua-11292	37	44	,	,	PUNCT
aiua-11292	37	45	patients	patient	NOUN
aiua-11292	37	46	receiving	receive	VERB
aiua-11292	37	47	systemic	systemic	ADJ
aiua-11292	37	48	therapy	therapy	NOUN
aiua-11292	37	49	for	for	ADP
aiua-11292	37	50	badder	badder	ADJ
aiua-11292	37	51	cancer	cancer	NOUN
aiua-11292	37	52	,	,	PUNCT
aiua-11292	37	53	patients	patient	NOUN
aiua-11292	37	54	with	with	ADP
aiua-11292	37	55	diabetes	diabetes	NOUN
aiua-11292	37	56	mellitus	mellitus	NOUN
aiua-11292	37	57	,	,	PUNCT
aiua-11292	37	58	chronic	chronic	ADJ
aiua-11292	37	59	kidney	kidney	NOUN
aiua-11292	37	60	disease	disease	NOUN
aiua-11292	37	61	,	,	PUNCT
aiua-11292	37	62	and	and	CCONJ
aiua-11292	37	63	cerebrovascular	cerebrovascular	ADJ
aiua-11292	37	64	disease	disease	NOUN
aiua-11292	37	65	.	.	PUNCT
aiua-11292	38	1	we	we	PRON
aiua-11292	38	2	did	do	VERB
aiua-11292	38	3	gender	gender	NOUN
aiua-11292	38	4	and	and	CCONJ
aiua-11292	38	5	age	age	NOUN
aiua-11292	38	6	mathcing	mathcing	NOUN
aiua-11292	38	7	between	between	ADP
aiua-11292	38	8	the	the	DET
aiua-11292	38	9	two	two	NUM
aiua-11292	38	10	groups	group	NOUN
aiua-11292	38	11	.	.	PUNCT
aiua-11292	39	1	all	all	DET
aiua-11292	39	2	subjects	subject	NOUN
aiua-11292	39	3	received	receive	VERB
aiua-11292	39	4	explanation	explanation	NOUN
aiua-11292	39	5	regarding	regard	VERB
aiua-11292	39	6	this	this	DET
aiua-11292	39	7	study	study	NOUN
aiua-11292	39	8	and	and	CCONJ
aiua-11292	39	9	were	be	AUX
aiua-11292	39	10	asked	ask	VERB
aiua-11292	39	11	to	to	PART
aiua-11292	39	12	sign	sign	VERB
aiua-11292	39	13	informed	informed	ADJ
aiua-11292	39	14	consent	consent	NOUN
aiua-11292	39	15	.	.	PUNCT
aiua-11292	40	1	subjects	subject	NOUN
aiua-11292	40	2	unwilling	unwilling	ADJ
aiua-11292	40	3	to	to	PART
aiua-11292	40	4	participate	participate	VERB
aiua-11292	40	5	in	in	ADP
aiua-11292	40	6	this	this	DET
aiua-11292	40	7	study	study	NOUN
aiua-11292	40	8	were	be	AUX
aiua-11292	40	9	excluded	exclude	VERB
aiua-11292	40	10	.	.	PUNCT
aiua-11292	41	1	serum	serum	NOUN
aiua-11292	41	2	sample	sample	NOUN
aiua-11292	41	3	was	be	AUX
aiua-11292	41	4	obtained	obtain	VERB
aiua-11292	41	5	from	from	ADP
aiua-11292	41	6	each	each	DET
aiua-11292	41	7	subject	subject	NOUN
aiua-11292	41	8	in	in	ADP
aiua-11292	41	9	case	case	NOUN
aiua-11292	41	10	group	group	NOUN
aiua-11292	41	11	.	.	PUNCT
aiua-11292	42	1	evaluation	evaluation	NOUN
aiua-11292	42	2	of	of	ADP
aiua-11292	42	3	serum	serum	NOUN
aiua-11292	42	4	hif-1α	hif-1α	NOUN
aiua-11292	42	5	level	level	NOUN
aiua-11292	42	6	was	be	AUX
aiua-11292	42	7	conducted	conduct	VERB
aiua-11292	42	8	at	at	ADP
aiua-11292	42	9	research	research	NOUN
aiua-11292	42	10	and	and	CCONJ
aiua-11292	42	11	esoteric	esoteric	ADJ
aiua-11292	42	12	laboratory	laboratory	NOUN
aiua-11292	42	13	jakarta	jakarta	PROPN
aiua-11292	42	14	,	,	PUNCT
aiua-11292	42	15	indonesia	indonesia	PROPN
aiua-11292	42	16	.	.	PUNCT
aiua-11292	43	1	we	we	PRON
aiua-11292	43	2	used	use	VERB
aiua-11292	43	3	hif-1α	hif-1α	PROPN
aiua-11292	43	4	human	human	PROPN
aiua-11292	43	5	elisa	elisa	PROPN
aiua-11292	43	6	kit	kit	PROPN
aiua-11292	43	7	(	(	PUNCT
aiua-11292	43	8	thermo	thermo	PROPN
aiua-11292	43	9	fisher	fisher	PROPN
aiua-11292	43	10	scientific	scientific	PROPN
aiua-11292	43	11	inc	inc	PROPN
aiua-11292	43	12	.	.	PROPN
aiua-11292	43	13	,	,	PUNCT
aiua-11292	43	14	waltham	waltham	PROPN
aiua-11292	43	15	,	,	PUNCT
aiua-11292	43	16	usa	usa	PROPN
aiua-11292	43	17	)	)	PUNCT
aiua-11292	43	18	to	to	PART
aiua-11292	43	19	determine	determine	VERB
aiua-11292	43	20	serum	serum	NOUN
aiua-11292	43	21	hif-1α	hif-1α	NOUN
aiua-11292	43	22	level	level	NOUN
aiua-11292	43	23	in	in	ADP
aiua-11292	43	24	this	this	DET
aiua-11292	43	25	study	study	NOUN
aiua-11292	43	26	.	.	PUNCT
aiua-11292	44	1	data	datum	NOUN
aiua-11292	44	2	was	be	AUX
aiua-11292	44	3	analyzed	analyze	VERB
aiua-11292	44	4	using	use	VERB
aiua-11292	44	5	statistical	statistical	ADJ
aiua-11292	44	6	package	package	NOUN
aiua-11292	44	7	for	for	ADP
aiua-11292	44	8	social	social	ADJ
aiua-11292	44	9	science	science	NOUN
aiua-11292	44	10	(	(	PUNCT
aiua-11292	44	11	spss	spss	ADJ
aiua-11292	44	12	)	)	PUNCT
aiua-11292	44	13	software	software	NOUN
aiua-11292	44	14	.	.	PUNCT
aiua-11292	45	1	categorical	categorical	ADJ
aiua-11292	45	2	data	datum	NOUN
aiua-11292	45	3	was	be	AUX
aiua-11292	45	4	presented	present	VERB
aiua-11292	45	5	in	in	ADP
aiua-11292	45	6	frequency	frequency	NOUN
aiua-11292	45	7	and	and	CCONJ
aiua-11292	45	8	percentage	percentage	NOUN
aiua-11292	45	9	while	while	SCONJ
aiua-11292	45	10	numerical	numerical	ADJ
aiua-11292	45	11	data	datum	NOUN
aiua-11292	45	12	was	be	AUX
aiua-11292	45	13	presented	present	VERB
aiua-11292	45	14	in	in	ADP
aiua-11292	45	15	median	median	PROPN
aiua-11292	45	16	and	and	CCONJ
aiua-11292	45	17	range	range	VERB
aiua-11292	45	18	if	if	SCONJ
aiua-11292	45	19	it	it	PRON
aiua-11292	45	20	was	be	AUX
aiua-11292	45	21	not	not	PART
aiua-11292	45	22	normally	normally	ADV
aiua-11292	45	23	distributed	distribute	VERB
aiua-11292	45	24	.	.	PUNCT
aiua-11292	46	1	otherwise	otherwise	ADV
aiua-11292	46	2	,	,	PUNCT
aiua-11292	46	3	it	it	PRON
aiua-11292	46	4	was	be	AUX
aiua-11292	46	5	presented	present	VERB
aiua-11292	46	6	in	in	ADP
aiua-11292	46	7	mean	mean	ADJ
aiua-11292	46	8	and	and	CCONJ
aiua-11292	46	9	standard	standard	ADJ
aiua-11292	46	10	deviation	deviation	NOUN
aiua-11292	46	11	.	.	PUNCT
aiua-11292	47	1	chi	chi	PROPN
aiua-11292	47	2	square	square	PROPN
aiua-11292	47	3	test	test	NOUN
aiua-11292	47	4	was	be	AUX
aiua-11292	47	5	utilized	utilize	VERB
aiua-11292	47	6	to	to	PART
aiua-11292	47	7	determine	determine	VERB
aiua-11292	47	8	relationship	relationship	NOUN
aiua-11292	47	9	between	between	ADP
aiua-11292	47	10	categorical	categorical	ADJ
aiua-11292	47	11	variables	variable	NOUN
aiua-11292	47	12	while	while	SCONJ
aiua-11292	47	13	mann	mann	PROPN
aiua-11292	47	14	whitney	whitney	PROPN
aiua-11292	47	15	and	and	CCONJ
aiua-11292	47	16	independent	independent	PROPN
aiua-11292	47	17	t	t	NOUN
aiua-11292	47	18	tests	test	NOUN
aiua-11292	47	19	were	be	AUX
aiua-11292	47	20	used	use	VERB
aiua-11292	47	21	to	to	PART
aiua-11292	47	22	determine	determine	VERB
aiua-11292	47	23	the	the	DET
aiua-11292	47	24	relationship	relationship	NOUN
aiua-11292	47	25	between	between	ADP
aiua-11292	47	26	categorical	categorical	ADJ
aiua-11292	47	27	and	and	CCONJ
aiua-11292	47	28	numerical	numerical	ADJ
aiua-11292	47	29	data	datum	NOUN
aiua-11292	47	30	.	.	PUNCT
aiua-11292	48	1	all	all	DET
aiua-11292	48	2	statistical	statistical	ADJ
aiua-11292	48	3	analyses	analysis	NOUN
aiua-11292	48	4	were	be	AUX
aiua-11292	48	5	conducted	conduct	VERB
aiua-11292	48	6	at	at	ADP
aiua-11292	48	7	confidence	confidence	NOUN
aiua-11292	48	8	interval	interval	NOUN
aiua-11292	48	9	of	of	ADP
aiua-11292	48	10	95	95	NUM
aiua-11292	48	11	%	%	NOUN
aiua-11292	48	12	.	.	PUNCT
aiua-11292	49	1	a	a	DET
aiua-11292	49	2	p	p	NOUN
aiua-11292	49	3	value	value	NOUN
aiua-11292	49	4	of	of	ADP
aiua-11292	49	5	<	<	X
aiua-11292	49	6	0.05	0.05	NUM
aiua-11292	49	7	was	be	AUX
aiua-11292	49	8	considered	consider	VERB
aiua-11292	49	9	significant	significant	ADJ
aiua-11292	49	10	.	.	PUNCT
aiua-11292	50	1	results	result	VERB
aiua-11292	50	2	a	a	DET
aiua-11292	50	3	total	total	NOUN
aiua-11292	50	4	of	of	ADP
aiua-11292	50	5	80	80	NUM
aiua-11292	50	6	subjects	subject	NOUN
aiua-11292	50	7	were	be	AUX
aiua-11292	50	8	enrolled	enrol	VERB
aiua-11292	50	9	in	in	ADP
aiua-11292	50	10	this	this	DET
aiua-11292	50	11	study	study	NOUN
aiua-11292	50	12	.	.	PUNCT
aiua-11292	51	1	all	all	DET
aiua-11292	51	2	subjects	subject	NOUN
aiua-11292	51	3	were	be	AUX
aiua-11292	51	4	divided	divide	VERB
aiua-11292	51	5	into	into	ADP
aiua-11292	51	6	the	the	DET
aiua-11292	51	7	two	two	NUM
aiua-11292	51	8	groups	group	NOUN
aiua-11292	51	9	equally	equally	ADV
aiua-11292	51	10	.	.	PUNCT
aiua-11292	52	1	in	in	ADP
aiua-11292	52	2	case	case	NOUN
aiua-11292	52	3	group	group	NOUN
aiua-11292	52	4	mean	mean	VERB
aiua-11292	52	5	age	age	NOUN
aiua-11292	52	6	of	of	ADP
aiua-11292	52	7	subjects	subject	NOUN
aiua-11292	52	8	was	be	AUX
aiua-11292	52	9	69.65	69.65	NUM
aiua-11292	52	10	years	year	NOUN
aiua-11292	52	11	and	and	CCONJ
aiua-11292	52	12	males	male	NOUN
aiua-11292	52	13	subjects	subject	NOUN
aiua-11292	52	14	were	be	AUX
aiua-11292	52	15	prevalent	prevalent	ADJ
aiua-11292	52	16	.	.	PUNCT
aiua-11292	53	1	most	most	ADJ
aiua-11292	53	2	subjects	subject	NOUN
aiua-11292	53	3	had	have	VERB
aiua-11292	53	4	advanced	advanced	ADJ
aiua-11292	53	5	primary	primary	ADJ
aiua-11292	53	6	tumor	tumor	NOUN
aiua-11292	53	7	and	and	CCONJ
aiua-11292	53	8	lymph	lymph	NOUN
aiua-11292	53	9	node	node	ADJ
aiua-11292	53	10	involvement	involvement	NOUN
aiua-11292	53	11	.	.	PUNCT
aiua-11292	54	1	only	only	ADV
aiua-11292	54	2	30	30	NUM
aiua-11292	54	3	%	%	NOUN
aiua-11292	54	4	subjects	subject	NOUN
aiua-11292	54	5	in	in	ADP
aiua-11292	54	6	the	the	DET
aiua-11292	54	7	case	case	NOUN
aiua-11292	54	8	group	group	NOUN
aiua-11292	54	9	had	have	AUX
aiua-11292	54	10	metastasized	metastasize	VERB
aiua-11292	54	11	ubc	ubc	PROPN
aiua-11292	54	12	.	.	PROPN
aiua-11292	55	1	significantly	significantly	ADV
aiua-11292	55	2	higher	high	ADJ
aiua-11292	55	3	serum	serum	NOUN
aiua-11292	55	4	hif-1α	hif-1α	NOUN
aiua-11292	55	5	level	level	NOUN
aiua-11292	55	6	was	be	AUX
aiua-11292	55	7	observed	observe	VERB
aiua-11292	55	8	in	in	ADP
aiua-11292	55	9	case	case	NOUN
aiua-11292	55	10	group	group	NOUN
aiua-11292	55	11	compared	compare	VERB
aiua-11292	55	12	to	to	ADP
aiua-11292	55	13	control	control	NOUN
aiua-11292	55	14	group	group	NOUN
aiua-11292	55	15	(	(	PUNCT
aiua-11292	55	16	table	table	NOUN
aiua-11292	55	17	1	1	NUM
aiua-11292	55	18	)	)	PUNCT
aiua-11292	55	19	.	.	PUNCT
aiua-11292	56	1	from	from	ADP
aiua-11292	56	2	statistical	statistical	ADJ
aiua-11292	56	3	analysis	analysis	NOUN
aiua-11292	56	4	,	,	PUNCT
aiua-11292	56	5	we	we	PRON
aiua-11292	56	6	found	find	VERB
aiua-11292	56	7	that	that	SCONJ
aiua-11292	56	8	serum	serum	NOUN
aiua-11292	56	9	hif-1α	hif-1α	NOUN
aiua-11292	56	10	level	level	NOUN
aiua-11292	56	11	was	be	AUX
aiua-11292	56	12	strongly	strongly	ADV
aiua-11292	56	13	associated	associate	VERB
aiua-11292	56	14	with	with	ADP
aiua-11292	56	15	metastatic	metastatic	ADJ
aiua-11292	56	16	ubc	ubc	PROPN
aiua-11292	56	17	(	(	PUNCT
aiua-11292	56	18	p	p	X
aiua-11292	56	19	<	<	X
aiua-11292	56	20	0.001	0.001	NUM
aiua-11292	56	21	)	)	PUNCT
aiua-11292	56	22	,	,	PUNCT
aiua-11292	56	23	followed	follow	VERB
aiua-11292	56	24	by	by	ADP
aiua-11292	56	25	ubc	ubc	PROPN
aiua-11292	56	26	with	with	ADP
aiua-11292	56	27	lymph	lymph	NOUN
aiua-11292	56	28	node	node	NOUN
aiua-11292	56	29	involvement	involvement	NOUN
aiua-11292	56	30	(	(	PUNCT
aiua-11292	56	31	p	p	NOUN
aiua-11292	56	32	=	=	NOUN
aiua-11292	56	33	0.005	0.005	NUM
aiua-11292	56	34	)	)	PUNCT
aiua-11292	56	35	and	and	CCONJ
aiua-11292	56	36	primary	primary	ADJ
aiua-11292	56	37	tumor	tumor	NOUN
aiua-11292	56	38	(	(	PUNCT
aiua-11292	56	39	p	p	NOUN
aiua-11292	56	40	=	=	NOUN
aiua-11292	56	41	0	0	NUM
aiua-11292	56	42	.	.	NOUN
aiua-11292	56	43	013	013	NUM
aiua-11292	56	44	)	)	PUNCT
aiua-11292	56	45	stage	stage	NOUN
aiua-11292	56	46	.	.	PUNCT
aiua-11292	57	1	overall	overall	ADV
aiua-11292	57	2	,	,	PUNCT
aiua-11292	57	3	serum	serum	NOUN
aiua-11292	57	4	hif-1α	hif-1α	NOUN
aiua-11292	57	5	level	level	NOUN
aiua-11292	57	6	was	be	AUX
aiua-11292	57	7	associated	associate	VERB
aiua-11292	57	8	with	with	ADP
aiua-11292	57	9	ubc	ubc	PROPN
aiua-11292	57	10	staging	stage	VERB
aiua-11292	57	11	(	(	PUNCT
aiua-11292	57	12	p	p	X
aiua-11292	57	13	=	=	NOUN
aiua-11292	57	14	0.008	0.008	NUM
aiua-11292	57	15	)	)	PUNCT
aiua-11292	57	16	but	but	CCONJ
aiua-11292	57	17	not	not	PART
aiua-11292	57	18	grading	grade	VERB
aiua-11292	57	19	(	(	PUNCT
aiua-11292	57	20	p	p	X
aiua-11292	57	21	=	=	NOUN
aiua-11292	57	22	0.134	0.134	NUM
aiua-11292	57	23	)	)	PUNCT
aiua-11292	57	24	(	(	PUNCT
aiua-11292	57	25	table	table	NOUN
aiua-11292	57	26	2	2	NUM
aiua-11292	57	27	)	)	PUNCT
aiua-11292	57	28	.	.	PUNCT
aiua-11292	58	1	discussion	discussion	NOUN
aiua-11292	58	2	as	as	SCONJ
aiua-11292	58	3	most	most	ADJ
aiua-11292	58	4	solid	solid	ADJ
aiua-11292	58	5	tumors	tumor	NOUN
aiua-11292	58	6	grow	grow	VERB
aiua-11292	58	7	,	,	PUNCT
aiua-11292	58	8	the	the	DET
aiua-11292	58	9	need	need	NOUN
aiua-11292	58	10	of	of	ADP
aiua-11292	58	11	oxygen	oxygen	NOUN
aiua-11292	58	12	for	for	ADP
aiua-11292	58	13	their	their	PRON
aiua-11292	58	14	metabolism	metabolism	NOUN
aiua-11292	58	15	is	be	AUX
aiua-11292	58	16	increased	increase	VERB
aiua-11292	58	17	.	.	PUNCT
aiua-11292	59	1	this	this	DET
aiua-11292	59	2	situation	situation	NOUN
aiua-11292	59	3	creates	create	VERB
aiua-11292	59	4	hypoxic	hypoxic	ADJ
aiua-11292	59	5	condition	condition	NOUN
aiua-11292	59	6	(	(	PUNCT
aiua-11292	59	7	6	6	NUM
aiua-11292	59	8	,	,	PUNCT
aiua-11292	59	9	10	10	NUM
aiua-11292	59	10	)	)	PUNCT
aiua-11292	59	11	.	.	PUNCT
aiua-11292	60	1	hypoxic	hypoxic	ADJ
aiua-11292	60	2	condition	condition	NOUN
aiua-11292	60	3	upregulates	upregulate	VERB
aiua-11292	60	4	several	several	ADJ
aiua-11292	60	5	proteins	protein	NOUN
aiua-11292	60	6	including	include	VERB
aiua-11292	60	7	hif-1α	hif-1α	NOUN
aiua-11292	60	8	that	that	SCONJ
aiua-11292	60	9	it	it	PRON
aiua-11292	60	10	is	be	AUX
aiua-11292	60	11	important	important	ADJ
aiua-11292	60	12	for	for	ADP
aiua-11292	60	13	adaptation	adaptation	NOUN
aiua-11292	60	14	of	of	ADP
aiua-11292	60	15	tumor	tumor	NOUN
aiua-11292	60	16	,	,	PUNCT
aiua-11292	60	17	including	include	VERB
aiua-11292	60	18	ubc	ubc	PROPN
aiua-11292	60	19	,	,	PUNCT
aiua-11292	60	20	in	in	ADP
aiua-11292	60	21	hypoxic	hypoxic	ADJ
aiua-11292	60	22	condition	condition	NOUN
aiua-11292	60	23	.	.	PUNCT
aiua-11292	61	1	angiogenesis	angiogenesis	NOUN
aiua-11292	61	2	or	or	CCONJ
aiua-11292	61	3	neovascularization	neovascularization	NOUN
aiua-11292	61	4	is	be	AUX
aiua-11292	61	5	the	the	DET
aiua-11292	61	6	end	end	NOUN
aiua-11292	61	7	point	point	NOUN
aiua-11292	61	8	of	of	ADP
aiua-11292	61	9	this	this	DET
aiua-11292	61	10	adaptation	adaptation	NOUN
aiua-11292	61	11	(	(	PUNCT
aiua-11292	61	12	3	3	NUM
aiua-11292	61	13	,	,	PUNCT
aiua-11292	61	14	4	4	NUM
aiua-11292	61	15	,	,	PUNCT
aiua-11292	61	16	6	6	NUM
aiua-11292	61	17	)	)	PUNCT
aiua-11292	61	18	,	,	PUNCT
aiua-11292	61	19	hypoxia	hypoxia	NOUN
aiua-11292	61	20	is	be	AUX
aiua-11292	61	21	also	also	ADV
aiua-11292	61	22	the	the	DET
aiua-11292	61	23	culprit	culprit	NOUN
aiua-11292	61	24	of	of	ADP
aiua-11292	61	25	treatment	treatment	NOUN
aiua-11292	61	26	resistance	resistance	NOUN
aiua-11292	61	27	in	in	ADP
aiua-11292	61	28	many	many	ADJ
aiua-11292	61	29	cancers	cancer	NOUN
aiua-11292	61	30	(	(	PUNCT
aiua-11292	61	31	8	8	NUM
aiua-11292	61	32	,	,	PUNCT
aiua-11292	61	33	10	10	NUM
aiua-11292	61	34	)	)	PUNCT
aiua-11292	61	35	and	and	CCONJ
aiua-11292	61	36	hif-1α	hif-1α	NOUN
aiua-11292	61	37	is	be	AUX
aiua-11292	61	38	one	one	NUM
aiua-11292	61	39	of	of	ADP
aiua-11292	61	40	the	the	DET
aiua-11292	61	41	underlying	underlie	VERB
aiua-11292	61	42	etiologies	etiology	NOUN
aiua-11292	61	43	(	(	PUNCT
aiua-11292	61	44	11	11	NUM
aiua-11292	61	45	-	-	SYM
aiua-11292	61	46	13	13	NUM
aiua-11292	61	47	)	)	PUNCT
aiua-11292	61	48	.	.	PUNCT
aiua-11292	62	1	binding	bind	VERB
aiua-11292	62	2	of	of	ADP
aiua-11292	62	3	hif-1α	hif-1α	NOUN
aiua-11292	62	4	with	with	ADP
aiua-11292	62	5	its	its	PRON
aiua-11292	62	6	receptor	receptor	NOUN
aiua-11292	62	7	in	in	ADP
aiua-11292	62	8	the	the	DET
aiua-11292	62	9	nucleus	nucleus	NOUN
aiua-11292	62	10	promotes	promote	VERB
aiua-11292	62	11	cell	cell	NOUN
aiua-11292	62	12	proliferation	proliferation	NOUN
aiua-11292	62	13	,	,	PUNCT
aiua-11292	62	14	migration	migration	NOUN
aiua-11292	62	15	,	,	PUNCT
aiua-11292	62	16	and	and	CCONJ
aiua-11292	62	17	invasion	invasion	NOUN
aiua-11292	62	18	.	.	PUNCT
aiua-11292	63	1	overexpression	overexpression	NOUN
aiua-11292	63	2	of	of	ADP
aiua-11292	63	3	hif-1α	hif-1α	NOUN
aiua-11292	63	4	is	be	AUX
aiua-11292	63	5	associated	associate	VERB
aiua-11292	63	6	with	with	ADP
aiua-11292	63	7	progression	progression	NOUN
aiua-11292	63	8	and	and	CCONJ
aiua-11292	63	9	recurrence	recurrence	NOUN
aiua-11292	63	10	of	of	ADP
aiua-11292	63	11	ubc	ubc	PROPN
aiua-11292	63	12	(	(	PUNCT
aiua-11292	63	13	4	4	NUM
aiua-11292	63	14	,	,	PUNCT
aiua-11292	63	15	6	6	NUM
aiua-11292	63	16	)	)	PUNCT
aiua-11292	63	17	.	.	PUNCT
aiua-11292	64	1	the	the	DET
aiua-11292	64	2	expression	expression	NOUN
aiua-11292	64	3	of	of	ADP
aiua-11292	64	4	hif-1α	hif-1α	NOUN
aiua-11292	64	5	in	in	ADP
aiua-11292	64	6	bladder	bladder	NOUN
aiua-11292	64	7	cancer	cancer	NOUN
aiua-11292	64	8	cells	cell	NOUN
aiua-11292	64	9	is	be	AUX
aiua-11292	64	10	also	also	ADV
aiua-11292	64	11	influenced	influence	VERB
aiua-11292	64	12	by	by	ADP
aiua-11292	64	13	several	several	ADJ
aiua-11292	64	14	other	other	ADJ
aiua-11292	64	15	factors	factor	NOUN
aiua-11292	64	16	,	,	PUNCT
aiua-11292	64	17	such	such	ADJ
aiua-11292	64	18	as	as	ADP
aiua-11292	64	19	elevated	elevated	ADJ
aiua-11292	64	20	serum	serum	NOUN
aiua-11292	64	21	copper	copper	NOUN
aiua-11292	64	22	level	level	NOUN
aiua-11292	64	23	and	and	CCONJ
aiua-11292	64	24	decreased	decrease	VERB
aiua-11292	64	25	serum	serum	NOUN
aiua-11292	64	26	zinc	zinc	NOUN
aiua-11292	64	27	level	level	NOUN
aiua-11292	64	28	(	(	PUNCT
aiua-11292	64	29	4	4	NUM
aiua-11292	64	30	)	)	PUNCT
aiua-11292	64	31	.	.	PUNCT
aiua-11292	65	1	in	in	ADP
aiua-11292	65	2	ubc	ubc	PROPN
aiua-11292	65	3	,	,	PUNCT
aiua-11292	65	4	hif-1α	hif-1α	NOUN
aiua-11292	65	5	expression	expression	NOUN
aiua-11292	65	6	was	be	AUX
aiua-11292	65	7	higher	high	ADJ
aiua-11292	65	8	compared	compare	VERB
aiua-11292	65	9	to	to	ADP
aiua-11292	65	10	normal	normal	ADJ
aiua-11292	65	11	tissue	tissue	NOUN
aiua-11292	65	12	(	(	PUNCT
aiua-11292	65	13	4	4	NUM
aiua-11292	65	14	,	,	PUNCT
aiua-11292	65	15	8)	8)	NUM
aiua-11292	65	16	.	.	PUNCT
aiua-11292	66	1	the	the	DET
aiua-11292	66	2	expression	expression	NOUN
aiua-11292	66	3	of	of	ADP
aiua-11292	66	4	hif-1α	hif-1α	NOUN
aiua-11292	66	5	in	in	ADP
aiua-11292	66	6	patients	patient	NOUN
aiua-11292	66	7	with	with	ADP
aiua-11292	66	8	bladder	bladder	NOUN
aiua-11292	66	9	cancer	cancer	NOUN
aiua-11292	66	10	was	be	AUX
aiua-11292	66	11	in	in	ADP
aiua-11292	66	12	line	line	NOUN
aiua-11292	66	13	with	with	ADP
aiua-11292	66	14	the	the	DET
aiua-11292	66	15	expression	expression	NOUN
aiua-11292	66	16	of	of	ADP
aiua-11292	66	17	vascular	vascular	ADJ
aiua-11292	66	18	endothelial	endothelial	ADJ
aiua-11292	66	19	growth	growth	NOUN
aiua-11292	66	20	factor	factor	NOUN
aiua-11292	66	21	(	(	PUNCT
aiua-11292	66	22	vegf	vegf	PROPN
aiua-11292	66	23	)	)	PUNCT
aiua-11292	67	1	(	(	PUNCT
aiua-11292	67	2	r	r	NOUN
aiua-11292	67	3	=	=	NOUN
aiua-11292	67	4	0.606	0.606	NUM
aiua-11292	67	5	)	)	PUNCT
aiua-11292	67	6	.	.	PUNCT
aiua-11292	68	1	we	we	PRON
aiua-11292	68	2	know	know	VERB
aiua-11292	68	3	that	that	SCONJ
aiua-11292	68	4	vegf	vegf	PROPN
aiua-11292	68	5	is	be	AUX
aiua-11292	68	6	important	important	ADJ
aiua-11292	68	7	in	in	ADP
aiua-11292	68	8	neovascularization	neovascularization	NOUN
aiua-11292	68	9	and	and	CCONJ
aiua-11292	68	10	growth	growth	NOUN
aiua-11292	68	11	of	of	ADP
aiua-11292	68	12	malignant	malignant	ADJ
aiua-11292	68	13	tissue	tissue	NOUN
aiua-11292	68	14	(	(	PUNCT
aiua-11292	68	15	4	4	NUM
aiua-11292	68	16	)	)	PUNCT
aiua-11292	68	17	.	.	PUNCT
aiua-11292	69	1	this	this	DET
aiua-11292	69	2	finding	finding	NOUN
aiua-11292	69	3	was	be	AUX
aiua-11292	69	4	confirmed	confirm	VERB
aiua-11292	69	5	by	by	ADP
aiua-11292	69	6	theodoropoulos	theodoropoulos	PROPN
aiua-11292	69	7	et	et	PROPN
aiua-11292	69	8	al	al	PROPN
aiua-11292	69	9	.	.	PROPN
aiua-11292	69	10	who	who	PRON
aiua-11292	69	11	found	find	VERB
aiua-11292	69	12	in	in	ADP
aiua-11292	69	13	their	their	PRON
aiua-11292	69	14	study	study	NOUN
aiua-11292	69	15	that	that	SCONJ
aiua-11292	69	16	hif-1α	hif-1α	NOUN
aiua-11292	69	17	was	be	AUX
aiua-11292	69	18	positively	positively	ADV
aiua-11292	69	19	associated	associate	VERB
aiua-11292	69	20	with	with	ADP
aiua-11292	69	21	histological	histological	ADJ
aiua-11292	69	22	grade	grade	NOUN
aiua-11292	69	23	of	of	ADP
aiua-11292	69	24	ubc	ubc	PROPN
aiua-11292	69	25	.	.	PUNCT
aiua-11292	70	1	this	this	DET
aiua-11292	70	2	association	association	NOUN
aiua-11292	70	3	was	be	AUX
aiua-11292	70	4	mediated	mediate	VERB
aiua-11292	70	5	by	by	ADP
aiua-11292	70	6	vegf	vegf	NOUN
aiua-11292	70	7	expression	expression	NOUN
aiua-11292	70	8	and	and	CCONJ
aiua-11292	70	9	microvessel	microvessel	NOUN
aiua-11292	70	10	density	density	NOUN
aiua-11292	70	11	(	(	PUNCT
aiua-11292	70	12	mvd	mvd	PROPN
aiua-11292	70	13	)	)	PUNCT
aiua-11292	70	14	.	.	PUNCT
aiua-11292	71	1	patients	patient	NOUN
aiua-11292	71	2	with	with	ADP
aiua-11292	71	3	high	high	ADJ
aiua-11292	71	4	hif-1α	hif-1α	NOUN
aiua-11292	71	5	expression	expression	NOUN
aiua-11292	71	6	tended	tend	VERB
aiua-11292	71	7	to	to	PART
aiua-11292	71	8	have	have	VERB
aiua-11292	71	9	advanced	advanced	ADJ
aiua-11292	71	10	disease	disease	NOUN
aiua-11292	71	11	and	and	CCONJ
aiua-11292	71	12	unfavorable	unfavorable	ADJ
aiua-11292	71	13	outcome	outcome	NOUN
aiua-11292	71	14	(	(	PUNCT
aiua-11292	71	15	8)	8)	NUM
aiua-11292	71	16	.	.	PUNCT
aiua-11292	72	1	badr	badr	PROPN
aiua-11292	72	2	et	et	PROPN
aiua-11292	72	3	al	al	PROPN
aiua-11292	72	4	.	.	PROPN
aiua-11292	72	5	also	also	ADV
aiua-11292	72	6	reported	report	VERB
aiua-11292	72	7	similar	similar	ADJ
aiua-11292	72	8	findings	finding	NOUN
aiua-11292	72	9	showing	show	VERB
aiua-11292	72	10	that	that	SCONJ
aiua-11292	72	11	hif-1α	hif-1α	NOUN
aiua-11292	72	12	expression	expression	NOUN
aiua-11292	72	13	is	be	AUX
aiua-11292	72	14	significantly	significantly	ADV
aiua-11292	72	15	higher	high	ADJ
aiua-11292	72	16	in	in	ADP
aiua-11292	72	17	patients	patient	NOUN
aiua-11292	72	18	with	with	ADP
aiua-11292	72	19	bladder	bladder	NOUN
aiua-11292	72	20	cancer	cancer	NOUN
aiua-11292	72	21	despite	despite	SCONJ
aiua-11292	72	22	its	its	PRON
aiua-11292	72	23	etiology	etiology	NOUN
aiua-11292	72	24	.	.	PUNCT
aiua-11292	73	1	the	the	DET
aiua-11292	73	2	level	level	NOUN
aiua-11292	73	3	of	of	ADP
aiua-11292	73	4	urinary	urinary	ADJ
aiua-11292	73	5	hif-1α	hif-1α	NOUN
aiua-11292	73	6	was	be	AUX
aiua-11292	73	7	also	also	ADV
aiua-11292	73	8	able	able	ADJ
aiua-11292	73	9	to	to	PART
aiua-11292	73	10	discriminate	discriminate	VERB
aiua-11292	73	11	between	between	ADP
aiua-11292	73	12	malignant	malignant	ADJ
aiua-11292	73	13	and	and	CCONJ
aiua-11292	73	14	non	non	ADJ
aiua-11292	73	15	-	-	ADJ
aiua-11292	73	16	malignant	malignant	ADJ
aiua-11292	73	17	tumor	tumor	NOUN
aiua-11292	73	18	with	with	ADP
aiua-11292	73	19	sensitivity	sensitivity	NOUN
aiua-11292	73	20	and	and	CCONJ
aiua-11292	73	21	specificity	specificity	NOUN
aiua-11292	73	22	of	of	ADP
aiua-11292	73	23	82.1	82.1	NUM
aiua-11292	73	24	%	%	NOUN
aiua-11292	73	25	and	and	CCONJ
aiua-11292	73	26	63.3	63.3	NUM
aiua-11292	73	27	%	%	NOUN
aiua-11292	73	28	,	,	PUNCT
aiua-11292	73	29	respectively	respectively	ADV
aiua-11292	73	30	.	.	PUNCT
aiua-11292	74	1	in	in	ADP
aiua-11292	74	2	contrast	contrast	NOUN
aiua-11292	74	3	with	with	ADP
aiua-11292	74	4	our	our	PRON
aiua-11292	74	5	results	result	NOUN
aiua-11292	74	6	,	,	PUNCT
aiua-11292	74	7	this	this	DET
aiua-11292	74	8	study	study	NOUN
aiua-11292	74	9	failed	fail	VERB
aiua-11292	74	10	to	to	PART
aiua-11292	74	11	demonstrate	demonstrate	VERB
aiua-11292	74	12	significant	significant	ADJ
aiua-11292	74	13	relationship	relationship	NOUN
aiua-11292	74	14	between	between	ADP
aiua-11292	74	15	hif-1α	hif-1α	PROPN
aiua-11292	74	16	and	and	CCONJ
aiua-11292	74	17	ubc	ubc	PROPN
aiua-11292	74	18	stage	stage	NOUN
aiua-11292	74	19	and	and	CCONJ
aiua-11292	74	20	grade	grade	NOUN
aiua-11292	74	21	(	(	PUNCT
aiua-11292	74	22	9	9	NUM
aiua-11292	74	23	)	)	PUNCT
aiua-11292	74	24	.	.	PUNCT
aiua-11292	75	1	table	table	NOUN
aiua-11292	75	2	1	1	NUM
aiua-11292	75	3	.	.	PUNCT
aiua-11292	75	4	baseline	baseline	PROPN
aiua-11292	75	5	characteristics	characteristic	NOUN
aiua-11292	75	6	of	of	ADP
aiua-11292	75	7	subjects	subject	NOUN
aiua-11292	75	8	.	.	PUNCT
aiua-11292	76	1	characteristics	characteristic	NOUN
aiua-11292	76	2	case	case	NOUN
aiua-11292	76	3	control	control	NOUN
aiua-11292	76	4	p	p	X
aiua-11292	76	5	(	(	PUNCT
aiua-11292	76	6	n	n	NOUN
aiua-11292	76	7	=	=	NUM
aiua-11292	76	8	40	40	NUM
aiua-11292	76	9	)	)	PUNCT
aiua-11292	76	10	(	(	PUNCT
aiua-11292	76	11	n	n	NOUN
aiua-11292	76	12	=	=	SYM
aiua-11292	76	13	40	40	NUM
aiua-11292	76	14	)	)	PUNCT
aiua-11292	76	15	mean	mean	VERB
aiua-11292	76	16	age	age	NOUN
aiua-11292	76	17	,	,	PUNCT
aiua-11292	76	18	years	year	NOUN
aiua-11292	76	19	±	±	NUM
aiua-11292	76	20	sd	sd	ADP
aiua-11292	76	21	69.65	69.65	NUM
aiua-11292	76	22	±	±	NUM
aiua-11292	76	23	7.01	7.01	NUM
aiua-11292	76	24	68.25	68.25	NUM
aiua-11292	76	25	±	±	NUM
aiua-11292	76	26	7.74	7.74	NUM
aiua-11292	76	27	0.400	0.400	NUM
aiua-11292	76	28	a	a	DET
aiua-11292	76	29	gender	gender	NOUN
aiua-11292	76	30	,	,	PUNCT
aiua-11292	76	31	n	n	CCONJ
aiua-11292	76	32	(	(	PUNCT
aiua-11292	76	33	%	%	INTJ
aiua-11292	76	34	)	)	PUNCT
aiua-11292	76	35	male	male	NOUN
aiua-11292	76	36	30	30	NUM
aiua-11292	76	37	(	(	PUNCT
aiua-11292	76	38	75	75	NUM
aiua-11292	76	39	%	%	NOUN
aiua-11292	76	40	)	)	PUNCT
aiua-11292	76	41	32	32	NUM
aiua-11292	76	42	(	(	PUNCT
aiua-11292	76	43	80	80	NUM
aiua-11292	76	44	)	)	PUNCT
aiua-11292	76	45	0.592	0.592	NUM
aiua-11292	76	46	a	a	DET
aiua-11292	76	47	female	female	ADJ
aiua-11292	76	48	10	10	NUM
aiua-11292	76	49	(	(	PUNCT
aiua-11292	76	50	25	25	NUM
aiua-11292	76	51	%	%	NOUN
aiua-11292	76	52	)	)	PUNCT
aiua-11292	76	53	8	8	NUM
aiua-11292	76	54	(	(	PUNCT
aiua-11292	76	55	20	20	NUM
aiua-11292	76	56	%	%	NOUN
aiua-11292	76	57	)	)	PUNCT
aiua-11292	76	58	primary	primary	ADJ
aiua-11292	76	59	tumor	tumor	NOUN
aiua-11292	76	60	stage	stage	NOUN
aiua-11292	76	61	(	(	PUNCT
aiua-11292	76	62	t	t	NOUN
aiua-11292	76	63	)	)	PUNCT
aiua-11292	76	64	,	,	PUNCT
aiua-11292	76	65	n	n	PROPN
aiua-11292	76	66	(	(	PUNCT
aiua-11292	76	67	%	%	INTJ
aiua-11292	76	68	)	)	PUNCT
aiua-11292	76	69	na	na	ADP
aiua-11292	76	70	na	na	X
aiua-11292	76	71	t1+t2	t1+t2	PROPN
aiua-11292	76	72	10	10	NUM
aiua-11292	76	73	(	(	PUNCT
aiua-11292	76	74	25	25	NUM
aiua-11292	76	75	%	%	NOUN
aiua-11292	76	76	)	)	PUNCT
aiua-11292	77	1	t3+t4	t3+t4	PROPN
aiua-11292	77	2	30	30	NUM
aiua-11292	77	3	(	(	PUNCT
aiua-11292	77	4	75	75	NUM
aiua-11292	77	5	%	%	NOUN
aiua-11292	77	6	)	)	PUNCT
aiua-11292	77	7	lymph	lymph	NOUN
aiua-11292	77	8	node	node	ADJ
aiua-11292	77	9	stage	stage	NOUN
aiua-11292	77	10	(	(	PUNCT
aiua-11292	77	11	n	n	CCONJ
aiua-11292	77	12	)	)	PUNCT
aiua-11292	77	13	,	,	PUNCT
aiua-11292	77	14	n	n	PROPN
aiua-11292	77	15	(	(	PUNCT
aiua-11292	77	16	%	%	INTJ
aiua-11292	77	17	)	)	PUNCT
aiua-11292	77	18	na	na	ADP
aiua-11292	77	19	na	na	PART
aiua-11292	77	20	n0	n0	NUM
aiua-11292	77	21	18	18	NUM
aiua-11292	77	22	(	(	PUNCT
aiua-11292	77	23	45	45	NUM
aiua-11292	77	24	%	%	NOUN
aiua-11292	77	25	)	)	PUNCT
aiua-11292	77	26	n1	n1	PROPN
aiua-11292	77	27	22	22	NUM
aiua-11292	77	28	(	(	PUNCT
aiua-11292	77	29	55	55	NUM
aiua-11292	77	30	%	%	NOUN
aiua-11292	77	31	)	)	PUNCT
aiua-11292	77	32	metastasis	metastasis	NOUN
aiua-11292	77	33	stage	stage	NOUN
aiua-11292	77	34	(	(	PUNCT
aiua-11292	77	35	m	m	NOUN
aiua-11292	77	36	)	)	PUNCT
aiua-11292	77	37	,	,	PUNCT
aiua-11292	77	38	n	n	PROPN
aiua-11292	77	39	(	(	PUNCT
aiua-11292	77	40	%	%	INTJ
aiua-11292	77	41	)	)	PUNCT
aiua-11292	77	42	na	na	ADP
aiua-11292	77	43	na	na	INTJ
aiua-11292	77	44	m0	m0	PROPN
aiua-11292	77	45	28	28	NUM
aiua-11292	77	46	(	(	PUNCT
aiua-11292	77	47	70	70	NUM
aiua-11292	77	48	%	%	NOUN
aiua-11292	77	49	)	)	PUNCT
aiua-11292	77	50	m1	m1	NOUN
aiua-11292	77	51	12	12	NUM
aiua-11292	77	52	(	(	PUNCT
aiua-11292	77	53	30	30	NUM
aiua-11292	77	54	%	%	NOUN
aiua-11292	77	55	)	)	PUNCT
aiua-11292	77	56	median	median	ADJ
aiua-11292	77	57	hif-1α	hif-1α	NOUN
aiua-11292	77	58	level	level	NOUN
aiua-11292	77	59	,	,	PUNCT
aiua-11292	77	60	pg	pg	INTJ
aiua-11292	77	61	/	/	SYM
aiua-11292	77	62	ml	ml	PROPN
aiua-11292	77	63	(	(	PUNCT
aiua-11292	77	64	range	range	NOUN
aiua-11292	77	65	)	)	PUNCT
aiua-11292	77	66	345	345	NUM
aiua-11292	77	67	(	(	PUNCT
aiua-11292	77	68	142	142	NUM
aiua-11292	77	69	-	-	NUM
aiua-11292	77	70	587	587	NUM
aiua-11292	77	71	)	)	PUNCT
aiua-11292	77	72	123	123	NUM
aiua-11292	77	73	(	(	PUNCT
aiua-11292	77	74	94	94	NUM
aiua-11292	77	75	-	-	SYM
aiua-11292	77	76	234	234	NUM
aiua-11292	77	77	)	)	PUNCT
aiua-11292	77	78	<	<	X
aiua-11292	77	79	0.001	0.001	NUM
aiua-11292	77	80	*	*	PUNCT
aiua-11292	77	81	b	b	X
aiua-11292	77	82	sd	sd	ADJ
aiua-11292	77	83	:	:	PUNCT
aiua-11292	77	84	standard	standard	ADJ
aiua-11292	77	85	deviation	deviation	NOUN
aiua-11292	77	86	;	;	PUNCT
aiua-11292	77	87	a	a	DET
aiua-11292	77	88	chi	chi	PROPN
aiua-11292	77	89	square	square	PROPN
aiua-11292	77	90	test	test	NOUN
aiua-11292	77	91	;	;	PUNCT
aiua-11292	77	92	b	b	X
aiua-11292	77	93	mann	mann	PROPN
aiua-11292	77	94	whitney	whitney	PROPN
aiua-11292	77	95	test	test	NOUN
aiua-11292	77	96	;	;	PUNCT
aiua-11292	77	97	*	*	PUNCT
aiua-11292	78	1	p	p	X
aiua-11292	78	2	<	<	X
aiua-11292	78	3	0.05	0.05	NUM
aiua-11292	78	4	.	.	PUNCT
aiua-11292	78	5	table	table	NOUN
aiua-11292	78	6	2	2	NUM
aiua-11292	78	7	.	.	X
aiua-11292	78	8	association	association	NOUN
aiua-11292	78	9	between	between	ADP
aiua-11292	78	10	serum	serum	NOUN
aiua-11292	78	11	hif-1α	hif-1α	NOUN
aiua-11292	78	12	level	level	NOUN
aiua-11292	78	13	and	and	CCONJ
aiua-11292	78	14	staging	staging	NOUN
aiua-11292	78	15	and	and	CCONJ
aiua-11292	78	16	grading	grading	NOUN
aiua-11292	78	17	of	of	ADP
aiua-11292	78	18	ubc	ubc	PROPN
aiua-11292	78	19	.	.	PUNCT
aiua-11292	79	1	variables	variable	NOUN
aiua-11292	79	2	mean	mean	VERB
aiua-11292	79	3	hif-1α	hif-1α	NOUN
aiua-11292	79	4	levels	level	NOUN
aiua-11292	79	5	,	,	PUNCT
aiua-11292	79	6	pg	pg	INTJ
aiua-11292	79	7	/	/	SYM
aiua-11292	79	8	ml	ml	NOUN
aiua-11292	79	9	±	±	NUM
aiua-11292	79	10	sd	sd	ADP
aiua-11292	79	11	p	p	PROPN
aiua-11292	79	12	primary	primary	ADJ
aiua-11292	79	13	tumor	tumor	NOUN
aiua-11292	79	14	stage	stage	NOUN
aiua-11292	79	15	(	(	PUNCT
aiua-11292	79	16	t	t	NOUN
aiua-11292	79	17	)	)	PUNCT
aiua-11292	79	18	t3+t4	t3+t4	PROPN
aiua-11292	79	19	389	389	NUM
aiua-11292	79	20	±	±	NUM
aiua-11292	79	21	126.66	126.66	NUM
aiua-11292	79	22	0.013	0.013	NUM
aiua-11292	79	23	*	*	PUNCT
aiua-11292	80	1	t1+t2	t1+t2	ADP
aiua-11292	80	2	273.4	273.4	NUM
aiua-11292	80	3	±	±	NUM
aiua-11292	80	4	103.89	103.89	NUM
aiua-11292	80	5	lymph	lymph	NOUN
aiua-11292	80	6	node	node	NOUN
aiua-11292	80	7	stage	stage	NOUN
aiua-11292	80	8	(	(	PUNCT
aiua-11292	80	9	n	n	CCONJ
aiua-11292	80	10	)	)	PUNCT
aiua-11292	80	11	n1	n1	NOUN
aiua-11292	80	12	410.45	410.45	NUM
aiua-11292	80	13	±	±	NOUN
aiua-11292	80	14	115.4	115.4	NUM
aiua-11292	80	15	0.005	0.005	NUM
aiua-11292	80	16	*	*	PUNCT
aiua-11292	80	17	n0	n0	NUM
aiua-11292	80	18	298.56	298.56	NUM
aiua-11292	80	19	±	±	NUM
aiua-11292	80	20	123.42	123.42	NUM
aiua-11292	80	21	metastasis	metastasis	NOUN
aiua-11292	80	22	stage	stage	NOUN
aiua-11292	80	23	(	(	PUNCT
aiua-11292	80	24	m	m	NOUN
aiua-11292	80	25	)	)	PUNCT
aiua-11292	80	26	m1	m1	NOUN
aiua-11292	80	27	477	477	NUM
aiua-11292	80	28	±	±	NUM
aiua-11292	80	29	95.16	95.16	NUM
aiua-11292	80	30	<	<	X
aiua-11292	80	31	0.001	0.001	NUM
aiua-11292	80	32	*	*	PUNCT
aiua-11292	80	33	m0	m0	PROPN
aiua-11292	80	34	310	310	NUM
aiua-11292	80	35	±	±	NUM
aiua-11292	80	36	110.34	110.34	NUM
aiua-11292	80	37	staging	staging	NOUN
aiua-11292	80	38	3	3	NUM
aiua-11292	80	39	+	+	ADP
aiua-11292	80	40	4	4	NUM
aiua-11292	80	41	395.67	395.67	NUM
aiua-11292	80	42	±	±	NUM
aiua-11292	80	43	124.11	124.11	NUM
aiua-11292	80	44	0.008	0.008	NUM
aiua-11292	80	45	*	*	NOUN
aiua-11292	80	46	1	1	NUM
aiua-11292	80	47	+	+	NUM
aiua-11292	80	48	2	2	NUM
aiua-11292	80	49	273.4	273.4	NUM
aiua-11292	80	50	±	±	NUM
aiua-11292	80	51	103.89	103.89	NUM
aiua-11292	80	52	grading	grade	VERB
aiua-11292	80	53	high	high	ADJ
aiua-11292	80	54	grade	grade	NOUN
aiua-11292	80	55	378	378	NUM
aiua-11292	80	56	±	±	NUM
aiua-11292	80	57	131.42	131.42	NUM
aiua-11292	80	58	0.134	0.134	NUM
aiua-11292	80	59	low	low	ADJ
aiua-11292	80	60	grade	grade	NOUN
aiua-11292	80	61	306.4	306.4	NUM
aiua-11292	80	62	±	±	NUM
aiua-11292	80	63	117.04	117.04	NUM
aiua-11292	80	64	sd	sd	NOUN
aiua-11292	80	65	:	:	PUNCT
aiua-11292	80	66	standard	standard	ADJ
aiua-11292	80	67	deviation	deviation	NOUN
aiua-11292	80	68	;	;	PUNCT
aiua-11292	80	69	*	*	PUNCT
aiua-11292	80	70	p	p	X
aiua-11292	80	71	<	<	X
aiua-11292	80	72	0.05	0.05	NUM
aiua-11292	80	73	.	.	PUNCT
aiua-11292	81	1	archivio	archivio	NOUN
aiua-11292	81	2	italiano	italiano	X
aiua-11292	81	3	di	di	PROPN
aiua-11292	81	4	urologia	urologia	PROPN
aiua-11292	81	5	e	e	PROPN
aiua-11292	81	6	andrologia	andrologia	NOUN
aiua-11292	81	7	2023	2023	NUM
aiua-11292	81	8	;	;	PUNCT
aiua-11292	81	9	95	95	NUM
aiua-11292	81	10	,	,	PUNCT
aiua-11292	81	11	2	2	NUM
aiua-11292	81	12	30	30	NUM
aiua-11292	81	13	serum	serum	NOUN
aiua-11292	81	14	hypoxia	hypoxia	NOUN
aiua-11292	81	15	inducible	inducible	ADJ
aiua-11292	81	16	factor-1α	factor-1α	NOUN
aiua-11292	81	17	level	level	NOUN
aiua-11292	81	18	and	and	CCONJ
aiua-11292	81	19	urothelial	urothelial	ADJ
aiua-11292	81	20	bladder	bladder	NOUN
aiua-11292	81	21	most	most	ADJ
aiua-11292	81	22	patients	patient	NOUN
aiua-11292	81	23	with	with	ADP
aiua-11292	81	24	ubc	ubc	PROPN
aiua-11292	81	25	expressed	express	VERB
aiua-11292	81	26	high	high	ADJ
aiua-11292	81	27	hif-1α	hif-1α	NOUN
aiua-11292	81	28	.	.	PUNCT
aiua-11292	82	1	tumor	tumor	NOUN
aiua-11292	82	2	size	size	NOUN
aiua-11292	82	3	,	,	PUNCT
aiua-11292	82	4	histological	histological	ADJ
aiua-11292	82	5	grade	grade	NOUN
aiua-11292	82	6	,	,	PUNCT
aiua-11292	82	7	tumor	tumor	NOUN
aiua-11292	82	8	invasion	invasion	NOUN
aiua-11292	82	9	,	,	PUNCT
aiua-11292	82	10	and	and	CCONJ
aiua-11292	82	11	recurrence	recurrence	NOUN
aiua-11292	82	12	of	of	ADP
aiua-11292	82	13	ubc	ubc	PROPN
aiua-11292	82	14	were	be	AUX
aiua-11292	82	15	also	also	ADV
aiua-11292	82	16	associated	associate	VERB
aiua-11292	82	17	with	with	ADP
aiua-11292	82	18	high	high	ADJ
aiua-11292	82	19	hif-1α	hif-1α	NOUN
aiua-11292	82	20	expression	expression	NOUN
aiua-11292	82	21	.	.	PUNCT
aiua-11292	83	1	in	in	ADP
aiua-11292	83	2	line	line	NOUN
aiua-11292	83	3	with	with	ADP
aiua-11292	83	4	previous	previous	ADJ
aiua-11292	83	5	study	study	NOUN
aiua-11292	83	6	,	,	PUNCT
aiua-11292	83	7	this	this	DET
aiua-11292	83	8	effect	effect	NOUN
aiua-11292	83	9	was	be	AUX
aiua-11292	83	10	linked	link	VERB
aiua-11292	83	11	to	to	ADP
aiua-11292	83	12	vegf	vegf	PROPN
aiua-11292	83	13	and	and	CCONJ
aiua-11292	83	14	mvd	mvd	PROPN
aiua-11292	83	15	.	.	PUNCT
aiua-11292	84	1	disease	disease	PROPN
aiua-11292	84	2	free	free	ADJ
aiua-11292	84	3	survival	survival	NOUN
aiua-11292	84	4	(	(	PUNCT
aiua-11292	84	5	dfs	dfs	PROPN
aiua-11292	84	6	)	)	PUNCT
aiua-11292	84	7	of	of	ADP
aiua-11292	84	8	ubc	ubc	PROPN
aiua-11292	84	9	was	be	AUX
aiua-11292	84	10	independently	independently	ADV
aiua-11292	84	11	influenced	influence	VERB
aiua-11292	84	12	by	by	ADP
aiua-11292	84	13	hif-1α	hif-1α	NOUN
aiua-11292	84	14	(	(	PUNCT
aiua-11292	84	15	p	p	NOUN
aiua-11292	84	16	=	=	NOUN
aiua-11292	84	17	0.011	0.011	NUM
aiua-11292	84	18	)	)	PUNCT
aiua-11292	84	19	(	(	PUNCT
aiua-11292	84	20	7	7	NUM
aiua-11292	84	21	)	)	PUNCT
aiua-11292	84	22	.	.	PUNCT
aiua-11292	85	1	deniz	deniz	PROPN
aiua-11292	85	2	,	,	PUNCT
aiua-11292	85	3	et	et	PROPN
aiua-11292	85	4	al	al	PROPN
aiua-11292	85	5	.	.	PROPN
aiua-11292	85	6	supported	support	VERB
aiua-11292	85	7	these	these	DET
aiua-11292	85	8	findings	finding	NOUN
aiua-11292	85	9	with	with	ADP
aiua-11292	85	10	their	their	PRON
aiua-11292	85	11	study	study	NOUN
aiua-11292	85	12	.	.	PUNCT
aiua-11292	86	1	immunoreactivity	immunoreactivity	NOUN
aiua-11292	86	2	of	of	ADP
aiua-11292	86	3	hif-1αwas	hif-1αwas	PROPN
aiua-11292	86	4	in	in	ADP
aiua-11292	86	5	concordance	concordance	NOUN
aiua-11292	86	6	with	with	ADP
aiua-11292	86	7	stage	stage	NOUN
aiua-11292	86	8	and	and	CCONJ
aiua-11292	86	9	histologic	histologic	ADJ
aiua-11292	86	10	grade	grade	NOUN
aiua-11292	86	11	of	of	ADP
aiua-11292	86	12	ubc	ubc	PROPN
aiua-11292	86	13	.	.	PROPN
aiua-11292	87	1	immunoreactivity	immunoreactivity	PROPN
aiua-11292	87	2	of	of	ADP
aiua-11292	87	3	hif-1α	hif-1α	NOUN
aiua-11292	87	4	was	be	AUX
aiua-11292	87	5	also	also	ADV
aiua-11292	87	6	related	relate	VERB
aiua-11292	87	7	to	to	ADP
aiua-11292	87	8	vegf	vegf	PROPN
aiua-11292	87	9	(	(	PUNCT
aiua-11292	87	10	p	p	X
aiua-11292	87	11	<	<	X
aiua-11292	87	12	0.001	0.001	NUM
aiua-11292	87	13	)	)	PUNCT
aiua-11292	87	14	and	and	CCONJ
aiua-11292	87	15	mvd	mvd	PROPN
aiua-11292	87	16	(	(	PUNCT
aiua-11292	87	17	p	p	NOUN
aiua-11292	87	18	=	=	NOUN
aiua-11292	87	19	0.002	0.002	NUM
aiua-11292	87	20	)	)	PUNCT
aiua-11292	87	21	(	(	PUNCT
aiua-11292	87	22	14	14	NUM
aiua-11292	87	23	)	)	PUNCT
aiua-11292	87	24	.	.	PUNCT
aiua-11292	88	1	another	another	DET
aiua-11292	88	2	study	study	NOUN
aiua-11292	88	3	by	by	ADP
aiua-11292	88	4	theodoropoulos	theodoropoulo	NOUN
aiua-11292	88	5	,	,	PUNCT
aiua-11292	88	6	et	et	PROPN
aiua-11292	88	7	al	al	PROPN
aiua-11292	88	8	.	.	PROPN
aiua-11292	89	1	in	in	ADP
aiua-11292	89	2	2005	2005	NUM
aiua-11292	89	3	reported	report	VERB
aiua-11292	89	4	that	that	SCONJ
aiua-11292	89	5	hif1α	hif1α	ADJ
aiua-11292	89	6	expression	expression	NOUN
aiua-11292	89	7	is	be	AUX
aiua-11292	89	8	more	more	ADV
aiua-11292	89	9	common	common	ADJ
aiua-11292	89	10	in	in	ADP
aiua-11292	89	11	high	high	ADJ
aiua-11292	89	12	grade	grade	NOUN
aiua-11292	89	13	ubc	ubc	PROPN
aiua-11292	89	14	.	.	PUNCT
aiua-11292	90	1	it	it	PRON
aiua-11292	90	2	was	be	AUX
aiua-11292	90	3	also	also	ADV
aiua-11292	90	4	positively	positively	ADV
aiua-11292	90	5	correlated	correlate	VERB
aiua-11292	90	6	with	with	ADP
aiua-11292	90	7	increased	increase	VERB
aiua-11292	90	8	proliferative	proliferative	ADJ
aiua-11292	90	9	activity	activity	NOUN
aiua-11292	90	10	,	,	PUNCT
aiua-11292	90	11	apoptotic	apoptotic	ADJ
aiua-11292	90	12	rate	rate	NOUN
aiua-11292	90	13	,	,	PUNCT
aiua-11292	90	14	and	and	CCONJ
aiua-11292	90	15	mvd	mvd	PROPN
aiua-11292	90	16	.	.	PUNCT
aiua-11292	91	1	however	however	ADV
aiua-11292	91	2	,	,	PUNCT
aiua-11292	91	3	they	they	PRON
aiua-11292	91	4	found	find	VERB
aiua-11292	91	5	no	no	DET
aiua-11292	91	6	association	association	NOUN
aiua-11292	91	7	between	between	ADP
aiua-11292	91	8	hif-1α	hif-1α	PROPN
aiua-11292	91	9	alone	alone	ADJ
aiua-11292	91	10	and	and	CCONJ
aiua-11292	91	11	prognosis	prognosis	NOUN
aiua-11292	91	12	of	of	ADP
aiua-11292	91	13	ubc	ubc	PROPN
aiua-11292	91	14	.	.	PUNCT
aiua-11292	92	1	the	the	DET
aiua-11292	92	2	prognosis	prognosis	NOUN
aiua-11292	92	3	of	of	ADP
aiua-11292	92	4	ubc	ubc	PROPN
aiua-11292	92	5	was	be	AUX
aiua-11292	92	6	associated	associate	VERB
aiua-11292	92	7	with	with	ADP
aiua-11292	92	8	both	both	PRON
aiua-11292	92	9	hif-1α	hif-1α	NOUN
aiua-11292	92	10	and	and	CCONJ
aiua-11292	92	11	mutation	mutation	NOUN
aiua-11292	92	12	in	in	ADP
aiua-11292	92	13	p53	p53	NOUN
aiua-11292	92	14	nuclear	nuclear	ADJ
aiua-11292	92	15	protein	protein	NOUN
aiua-11292	92	16	(	(	PUNCT
aiua-11292	92	17	5	5	NUM
aiua-11292	92	18	)	)	PUNCT
aiua-11292	92	19	.	.	PUNCT
aiua-11292	93	1	a	a	DET
aiua-11292	93	2	study	study	NOUN
aiua-11292	93	3	conducted	conduct	VERB
aiua-11292	93	4	by	by	ADP
aiua-11292	93	5	fus	fus	PROPN
aiua-11292	93	6	,	,	PUNCT
aiua-11292	93	7	et	et	PROPN
aiua-11292	93	8	al	al	PROPN
aiua-11292	93	9	.	.	PROPN
aiua-11292	93	10	reported	report	VERB
aiua-11292	93	11	a	a	DET
aiua-11292	93	12	contradictive	contradictive	ADJ
aiua-11292	93	13	result	result	NOUN
aiua-11292	93	14	.	.	PUNCT
aiua-11292	94	1	they	they	PRON
aiua-11292	94	2	found	find	VERB
aiua-11292	94	3	that	that	SCONJ
aiua-11292	94	4	the	the	DET
aiua-11292	94	5	expression	expression	NOUN
aiua-11292	94	6	of	of	ADP
aiua-11292	94	7	hif-1α	hif-1α	NOUN
aiua-11292	94	8	is	be	AUX
aiua-11292	94	9	significantly	significantly	ADV
aiua-11292	94	10	lower	low	ADJ
aiua-11292	94	11	in	in	ADP
aiua-11292	94	12	high	high	ADJ
aiua-11292	94	13	grade	grade	NOUN
aiua-11292	94	14	ubc	ubc	PROPN
aiua-11292	94	15	.	.	PROPN
aiua-11292	95	1	negative	negative	ADJ
aiua-11292	95	2	correlation	correlation	NOUN
aiua-11292	95	3	was	be	AUX
aiua-11292	95	4	also	also	ADV
aiua-11292	95	5	reported	report	VERB
aiua-11292	95	6	between	between	ADP
aiua-11292	95	7	the	the	DET
aiua-11292	95	8	expression	expression	NOUN
aiua-11292	95	9	of	of	ADP
aiua-11292	95	10	hif-1α	hif-1α	PROPN
aiua-11292	95	11	and	and	CCONJ
aiua-11292	95	12	mvd	mvd	PROPN
aiua-11292	95	13	(	(	PUNCT
aiua-11292	95	14	3	3	NUM
aiua-11292	95	15	)	)	PUNCT
aiua-11292	95	16	.	.	PUNCT
aiua-11292	96	1	we	we	PRON
aiua-11292	96	2	found	find	VERB
aiua-11292	96	3	that	that	SCONJ
aiua-11292	96	4	serum	serum	NOUN
aiua-11292	96	5	level	level	NOUN
aiua-11292	96	6	of	of	ADP
aiua-11292	96	7	hif-1α	hif-1α	NOUN
aiua-11292	96	8	in	in	ADP
aiua-11292	96	9	case	case	NOUN
aiua-11292	96	10	group	group	NOUN
aiua-11292	96	11	is	be	AUX
aiua-11292	96	12	significantly	significantly	ADV
aiua-11292	96	13	higher	high	ADJ
aiua-11292	96	14	compared	compare	VERB
aiua-11292	96	15	to	to	ADP
aiua-11292	96	16	control	control	NOUN
aiua-11292	96	17	group	group	NOUN
aiua-11292	96	18	(	(	PUNCT
aiua-11292	96	19	p	p	X
aiua-11292	96	20	<	<	X
aiua-11292	96	21	0.001	0.001	NUM
aiua-11292	96	22	)	)	PUNCT
aiua-11292	96	23	.	.	PUNCT
aiua-11292	97	1	serum	serum	PROPN
aiua-11292	97	2	hif-1α	hif-1α	PROPN
aiua-11292	97	3	was	be	AUX
aiua-11292	97	4	also	also	ADV
aiua-11292	97	5	higher	high	ADJ
aiua-11292	97	6	in	in	ADP
aiua-11292	97	7	advanced	advanced	ADJ
aiua-11292	97	8	ubc	ubc	PROPN
aiua-11292	97	9	stage	stage	NOUN
aiua-11292	97	10	,	,	PUNCT
aiua-11292	97	11	including	include	VERB
aiua-11292	97	12	primary	primary	ADJ
aiua-11292	97	13	tumor	tumor	NOUN
aiua-11292	97	14	,	,	PUNCT
aiua-11292	97	15	lymph	lymph	NOUN
aiua-11292	97	16	node	node	NOUN
aiua-11292	97	17	,	,	PUNCT
aiua-11292	97	18	and	and	CCONJ
aiua-11292	97	19	metastasis	metastasis	NOUN
aiua-11292	97	20	stage	stage	NOUN
aiua-11292	97	21	.	.	PUNCT
aiua-11292	98	1	higher	high	ADJ
aiua-11292	98	2	serum	serum	NOUN
aiua-11292	98	3	hif-1αwas	hif-1αwas	PRON
aiua-11292	98	4	also	also	ADV
aiua-11292	98	5	observed	observe	VERB
aiua-11292	98	6	in	in	ADP
aiua-11292	98	7	advanced	advanced	ADJ
aiua-11292	98	8	ubc	ubc	PROPN
aiua-11292	98	9	grade	grade	NOUN
aiua-11292	98	10	but	but	CCONJ
aiua-11292	98	11	the	the	DET
aiua-11292	98	12	difference	difference	NOUN
aiua-11292	98	13	was	be	AUX
aiua-11292	98	14	not	not	PART
aiua-11292	98	15	statistically	statistically	ADV
aiua-11292	98	16	significant	significant	ADJ
aiua-11292	98	17	.	.	PUNCT
aiua-11292	99	1	there	there	PRON
aiua-11292	99	2	were	be	VERB
aiua-11292	99	3	several	several	ADJ
aiua-11292	99	4	limitations	limitation	NOUN
aiua-11292	99	5	in	in	ADP
aiua-11292	99	6	our	our	PRON
aiua-11292	99	7	study	study	NOUN
aiua-11292	99	8	.	.	PUNCT
aiua-11292	100	1	we	we	PRON
aiua-11292	100	2	did	do	AUX
aiua-11292	100	3	not	not	PART
aiua-11292	100	4	analyze	analyze	VERB
aiua-11292	100	5	risk	risk	NOUN
aiua-11292	100	6	factors	factor	NOUN
aiua-11292	100	7	for	for	ADP
aiua-11292	100	8	ubc	ubc	PROPN
aiua-11292	100	9	other	other	ADJ
aiua-11292	100	10	than	than	ADP
aiua-11292	100	11	gender	gender	NOUN
aiua-11292	100	12	and	and	CCONJ
aiua-11292	100	13	age	age	NOUN
aiua-11292	100	14	.	.	PUNCT
aiua-11292	101	1	we	we	PRON
aiua-11292	101	2	also	also	ADV
aiua-11292	101	3	did	do	AUX
aiua-11292	101	4	not	not	PART
aiua-11292	101	5	analyze	analyze	VERB
aiua-11292	101	6	variables	variable	NOUN
aiua-11292	101	7	that	that	PRON
aiua-11292	101	8	influence	influence	VERB
aiua-11292	101	9	the	the	DET
aiua-11292	101	10	level	level	NOUN
aiua-11292	101	11	of	of	ADP
aiua-11292	101	12	serum	serum	PROPN
aiua-11292	101	13	hif-1α	hif-1α	PROPN
aiua-11292	101	14	.	.	PUNCT
aiua-11292	102	1	the	the	DET
aiua-11292	102	2	kit	kit	NOUN
aiua-11292	102	3	we	we	PRON
aiua-11292	102	4	used	use	VERB
aiua-11292	102	5	to	to	PART
aiua-11292	102	6	determine	determine	VERB
aiua-11292	102	7	serum	serum	NOUN
aiua-11292	102	8	hif1α	hif1α	ADJ
aiua-11292	102	9	level	level	NOUN
aiua-11292	102	10	was	be	AUX
aiua-11292	102	11	also	also	ADV
aiua-11292	102	12	different	different	ADJ
aiua-11292	102	13	which	which	PRON
aiua-11292	102	14	may	may	AUX
aiua-11292	102	15	have	have	AUX
aiua-11292	102	16	given	give	VERB
aiua-11292	102	17	different	different	ADJ
aiua-11292	102	18	result	result	NOUN
aiua-11292	102	19	.	.	PUNCT
aiua-11292	103	1	additional	additional	ADJ
aiua-11292	103	2	study	study	NOUN
aiua-11292	103	3	,	,	PUNCT
aiua-11292	103	4	preferably	preferably	ADV
aiua-11292	103	5	a	a	DET
aiua-11292	103	6	meta	meta	ADJ
aiua-11292	103	7	-	-	PUNCT
aiua-11292	103	8	analysis	analysis	NOUN
aiua-11292	103	9	,	,	PUNCT
aiua-11292	103	10	is	be	AUX
aiua-11292	103	11	requested	request	VERB
aiua-11292	103	12	to	to	PART
aiua-11292	103	13	determine	determine	VERB
aiua-11292	103	14	the	the	DET
aiua-11292	103	15	association	association	NOUN
aiua-11292	103	16	between	between	ADP
aiua-11292	103	17	serum	serum	NOUN
aiua-11292	103	18	hif-1α	hif-1α	NOUN
aiua-11292	103	19	level	level	NOUN
aiua-11292	103	20	and	and	CCONJ
aiua-11292	103	21	progression	progression	NOUN
aiua-11292	103	22	of	of	ADP
aiua-11292	103	23	ubc	ubc	PROPN
aiua-11292	103	24	.	.	PUNCT
aiua-11292	104	1	conclusions	conclusion	NOUN
aiua-11292	104	2	there	there	PRON
aiua-11292	104	3	was	be	VERB
aiua-11292	104	4	a	a	DET
aiua-11292	104	5	significant	significant	ADJ
aiua-11292	104	6	association	association	NOUN
aiua-11292	104	7	between	between	ADP
aiua-11292	104	8	serum	serum	NOUN
aiua-11292	104	9	hif1α	hif1α	ADJ
aiua-11292	104	10	level	level	NOUN
aiua-11292	104	11	and	and	CCONJ
aiua-11292	104	12	staging	staging	NOUN
aiua-11292	104	13	of	of	ADP
aiua-11292	104	14	ubc	ubc	PROPN
aiua-11292	104	15	.	.	PROPN
aiua-11292	104	16	serum	serum	PROPN
aiua-11292	104	17	hif-1α	hif-1α	PROPN
aiua-11292	104	18	level	level	NOUN
aiua-11292	104	19	may	may	AUX
aiua-11292	104	20	aid	aid	VERB
aiua-11292	104	21	in	in	ADP
aiua-11292	104	22	early	early	ADJ
aiua-11292	104	23	diagnosis	diagnosis	NOUN
aiua-11292	104	24	,	,	PUNCT
aiua-11292	104	25	prompt	prompt	ADJ
aiua-11292	104	26	management	management	NOUN
aiua-11292	104	27	,	,	PUNCT
aiua-11292	104	28	and	and	CCONJ
aiua-11292	104	29	improved	improved	ADJ
aiua-11292	104	30	outcome	outcome	NOUN
aiua-11292	104	31	of	of	ADP
aiua-11292	104	32	patients	patient	NOUN
aiua-11292	104	33	with	with	ADP
aiua-11292	104	34	ubc	ubc	PROPN
aiua-11292	104	35	.	.	PROPN
aiua-11292	104	36	references	reference	NOUN
aiua-11292	104	37	1	1	NUM
aiua-11292	104	38	.	.	PUNCT
aiua-11292	104	39	burger	burger	PROPN
aiua-11292	104	40	m	m	PROPN
aiua-11292	104	41	,	,	PUNCT
aiua-11292	104	42	catto	catto	VERB
aiua-11292	104	43	jwf	jwf	ADV
aiua-11292	104	44	,	,	PUNCT
aiua-11292	104	45	dalbagni	dalbagni	NOUN
aiua-11292	104	46	g	g	PROPN
aiua-11292	104	47	,	,	PUNCT
aiua-11292	104	48	et	et	PROPN
aiua-11292	104	49	al	al	PROPN
aiua-11292	104	50	.	.	PUNCT
aiua-11292	105	1	epidemiology	epidemiology	NOUN
aiua-11292	105	2	and	and	CCONJ
aiua-11292	105	3	risk	risk	NOUN
aiua-11292	105	4	factors	factor	NOUN
aiua-11292	105	5	of	of	ADP
aiua-11292	105	6	urothelial	urothelial	ADJ
aiua-11292	105	7	bladder	bladder	NOUN
aiua-11292	105	8	cancer	cancer	NOUN
aiua-11292	105	9	.	.	PUNCT
aiua-11292	106	1	eur	eur	PROPN
aiua-11292	106	2	urol	urol	PROPN
aiua-11292	106	3	.	.	PUNCT
aiua-11292	107	1	2013	2013	NUM
aiua-11292	107	2	;	;	PUNCT
aiua-11292	107	3	63:234	63:234	NUM
aiua-11292	107	4	-	-	SYM
aiua-11292	107	5	41	41	NUM
aiua-11292	107	6	.	.	NOUN
aiua-11292	108	1	2	2	NUM
aiua-11292	108	2	.	.	X
aiua-11292	108	3	martin	martin	PROPN
aiua-11292	108	4	jw	jw	PROPN
aiua-11292	108	5	,	,	PUNCT
aiua-11292	108	6	jefferson	jefferson	PROPN
aiua-11292	108	7	fa	fa	PROPN
aiua-11292	108	8	,	,	PUNCT
aiua-11292	108	9	huang	huang	PROPN
aiua-11292	108	10	m	m	PROPN
aiua-11292	108	11	,	,	PUNCT
aiua-11292	108	12	et	et	PROPN
aiua-11292	108	13	al	al	PROPN
aiua-11292	108	14	.	.	PUNCT
aiua-11292	109	1	a	a	DET
aiua-11292	109	2	california	california	PROPN
aiua-11292	109	3	cancer	cancer	NOUN
aiua-11292	109	4	registry	registry	NOUN
aiua-11292	109	5	analysis	analysis	NOUN
aiua-11292	109	6	of	of	ADP
aiua-11292	109	7	urothelial	urothelial	ADJ
aiua-11292	109	8	and	and	CCONJ
aiua-11292	109	9	non	non	ADJ
aiua-11292	109	10	-	-	ADJ
aiua-11292	109	11	urothelial	urothelial	ADJ
aiua-11292	109	12	bladder	bladder	NOUN
aiua-11292	109	13	cancer	cancer	NOUN
aiua-11292	109	14	subtypes	subtype	NOUN
aiua-11292	109	15	:	:	PUNCT
aiua-11292	109	16	epidemiology	epidemiology	NOUN
aiua-11292	109	17	,	,	PUNCT
aiua-11292	109	18	treatment	treatment	NOUN
aiua-11292	109	19	,	,	PUNCT
aiua-11292	109	20	and	and	CCONJ
aiua-11292	109	21	survival	survival	NOUN
aiua-11292	109	22	.	.	PUNCT
aiua-11292	110	1	clin	clin	PROPN
aiua-11292	110	2	genitourin	genitourin	PROPN
aiua-11292	110	3	cancer	cancer	NOUN
aiua-11292	110	4	.	.	PUNCT
aiua-11292	111	1	2020	2020	NUM
aiua-11292	111	2	;	;	PUNCT
aiua-11292	111	3	18	18	NUM
aiua-11292	111	4	:	:	PUNCT
aiua-11292	111	5	e330	e330	PROPN
aiua-11292	111	6	-	-	SYM
aiua-11292	111	7	6	6	NUM
aiua-11292	111	8	.	.	NOUN
aiua-11292	112	1	3	3	NUM
aiua-11292	112	2	.	.	X
aiua-11292	112	3	fus	fus	PROPN
aiua-11292	112	4	lp	lp	ADV
aiua-11292	112	5	,	,	PUNCT
aiua-11292	112	6	pihowicz	pihowicz	VERB
aiua-11292	112	7	p	p	NOUN
aiua-11292	112	8	,	,	PUNCT
aiua-11292	112	9	koperski	koperski	PROPN
aiua-11292	112	10	l	l	PROPN
aiua-11292	112	11	,	,	PUNCT
aiua-11292	112	12	et	et	PROPN
aiua-11292	112	13	al	al	PROPN
aiua-11292	112	14	.	.	PUNCT
aiua-11292	113	1	hif-1α	hif-1α	NOUN
aiua-11292	113	2	expression	expression	NOUN
aiua-11292	113	3	is	be	AUX
aiua-11292	113	4	inversely	inversely	ADV
aiua-11292	113	5	associated	associate	VERB
aiua-11292	113	6	with	with	ADP
aiua-11292	113	7	tumor	tumor	NOUN
aiua-11292	113	8	stage	stage	NOUN
aiua-11292	113	9	,	,	PUNCT
aiua-11292	113	10	grade	grade	NOUN
aiua-11292	113	11	and	and	CCONJ
aiua-11292	113	12	microvessel	microvessel	NOUN
aiua-11292	113	13	density	density	NOUN
aiua-11292	113	14	in	in	ADP
aiua-11292	113	15	urothelial	urothelial	ADJ
aiua-11292	113	16	bladder	bladder	NOUN
aiua-11292	113	17	carcinoma	carcinoma	NOUN
aiua-11292	113	18	.	.	PUNCT
aiua-11292	114	1	pol	pol	PROPN
aiua-11292	114	2	j	j	PROPN
aiua-11292	114	3	pathol	pathol	PROPN
aiua-11292	114	4	.	.	PUNCT
aiua-11292	115	1	2018	2018	NUM
aiua-11292	115	2	;	;	PUNCT
aiua-11292	115	3	69:395	69:395	PROPN
aiua-11292	115	4	-	-	SYM
aiua-11292	115	5	404	404	NUM
aiua-11292	115	6	.	.	PUNCT
aiua-11292	116	1	4	4	X
aiua-11292	116	2	.	.	X
aiua-11292	116	3	mortada	mortada	PROPN
aiua-11292	116	4	wi	wi	PROPN
aiua-11292	116	5	,	,	PUNCT
aiua-11292	116	6	awadalla	awadalla	NOUN
aiua-11292	116	7	a	a	NOUN
aiua-11292	116	8	,	,	PUNCT
aiua-11292	116	9	khater	khater	NOUN
aiua-11292	116	10	s	s	PROPN
aiua-11292	116	11	,	,	PUNCT
aiua-11292	116	12	et	et	PROPN
aiua-11292	116	13	al	al	PROPN
aiua-11292	116	14	.	.	PROPN
aiua-11292	116	15	copper	copper	NOUN
aiua-11292	116	16	and	and	CCONJ
aiua-11292	116	17	zinc	zinc	NOUN
aiua-11292	116	18	levels	level	NOUN
aiua-11292	116	19	in	in	ADP
aiua-11292	116	20	plasma	plasma	NOUN
aiua-11292	116	21	and	and	CCONJ
aiua-11292	116	22	cancerous	cancerous	ADJ
aiua-11292	116	23	tissues	tissue	NOUN
aiua-11292	116	24	and	and	CCONJ
aiua-11292	116	25	their	their	PRON
aiua-11292	116	26	relation	relation	NOUN
aiua-11292	116	27	with	with	ADP
aiua-11292	116	28	expression	expression	NOUN
aiua-11292	116	29	of	of	ADP
aiua-11292	116	30	vegf	vegf	PROPN
aiua-11292	116	31	and	and	CCONJ
aiua-11292	116	32	hif-1	hif-1	ADV
aiua-11292	116	33	in	in	ADP
aiua-11292	116	34	the	the	DET
aiua-11292	116	35	pathogenesis	pathogenesis	NOUN
aiua-11292	116	36	of	of	ADP
aiua-11292	116	37	muscle	muscle	NOUN
aiua-11292	116	38	invasive	invasive	ADJ
aiua-11292	116	39	urothelial	urothelial	ADJ
aiua-11292	116	40	bladder	bladder	NOUN
aiua-11292	116	41	cancer	cancer	NOUN
aiua-11292	116	42	:	:	PUNCT
aiua-11292	116	43	a	a	DET
aiua-11292	116	44	case	case	NOUN
aiua-11292	116	45	-	-	PUNCT
aiua-11292	116	46	controlled	control	VERB
aiua-11292	116	47	clinical	clinical	ADJ
aiua-11292	116	48	study	study	NOUN
aiua-11292	116	49	.	.	PUNCT
aiua-11292	117	1	environ	environ	PROPN
aiua-11292	117	2	sci	sci	PROPN
aiua-11292	117	3	pollut	pollut	PROPN
aiua-11292	117	4	res	re	NOUN
aiua-11292	117	5	int	int	NOUN
aiua-11292	117	6	.	.	PUNCT
aiua-11292	118	1	2020	2020	NUM
aiua-11292	118	2	;	;	PUNCT
aiua-11292	118	3	27:15835	27:15835	NUM
aiua-11292	118	4	-	-	SYM
aiua-11292	118	5	41	41	NUM
aiua-11292	118	6	.	.	PUNCT
aiua-11292	119	1	5	5	NUM
aiua-11292	119	2	.	.	X
aiua-11292	119	3	theodoropoulos	theodoropoulos	PROPN
aiua-11292	119	4	ve	ve	PROPN
aiua-11292	119	5	,	,	PUNCT
aiua-11292	119	6	lazaris	lazaris	PROPN
aiua-11292	119	7	ac	ac	PROPN
aiua-11292	119	8	,	,	PUNCT
aiua-11292	119	9	kastriotis	kastriotis	PROPN
aiua-11292	119	10	i	i	PROPN
aiua-11292	119	11	,	,	PUNCT
aiua-11292	119	12	et	et	PROPN
aiua-11292	119	13	al	al	PROPN
aiua-11292	119	14	.	.	PUNCT
aiua-11292	119	15	evaluation	evaluation	NOUN
aiua-11292	119	16	of	of	ADP
aiua-11292	119	17	hypoxia	hypoxia	NOUN
aiua-11292	119	18	-	-	PUNCT
aiua-11292	119	19	inducible	inducible	ADJ
aiua-11292	119	20	factor	factor	NOUN
aiua-11292	119	21	1	1	NUM
aiua-11292	119	22	alpha	alpha	NOUN
aiua-11292	119	23	overexpression	overexpression	NOUN
aiua-11292	119	24	as	as	ADP
aiua-11292	119	25	a	a	DET
aiua-11292	119	26	predictor	predictor	NOUN
aiua-11292	119	27	of	of	ADP
aiua-11292	119	28	tumour	tumour	NOUN
aiua-11292	119	29	recurrence	recurrence	NOUN
aiua-11292	119	30	and	and	CCONJ
aiua-11292	119	31	progression	progression	NOUN
aiua-11292	119	32	in	in	ADP
aiua-11292	119	33	superficial	superficial	ADJ
aiua-11292	119	34	urothelial	urothelial	ADJ
aiua-11292	119	35	bladder	bladder	NOUN
aiua-11292	119	36	carcinoma	carcinoma	NOUN
aiua-11292	119	37	.	.	PUNCT
aiua-11292	120	1	bju	bju	NOUN
aiua-11292	120	2	int	int	PROPN
aiua-11292	120	3	.	.	PUNCT
aiua-11292	121	1	2005	2005	NUM
aiua-11292	121	2	;	;	PUNCT
aiua-11292	121	3	95:425	95:425	NUM
aiua-11292	121	4	-	-	SYM
aiua-11292	121	5	31	31	NUM
aiua-11292	121	6	.	.	PUNCT
aiua-11292	122	1	6	6	NUM
aiua-11292	122	2	.	.	X
aiua-11292	122	3	xue	xue	PROPN
aiua-11292	122	4	m	m	PROPN
aiua-11292	122	5	,	,	PUNCT
aiua-11292	122	6	li	li	PROPN
aiua-11292	122	7	x	x	PROPN
aiua-11292	122	8	,	,	PUNCT
aiua-11292	122	9	li	li	PROPN
aiua-11292	122	10	z	z	PROPN
aiua-11292	122	11	,	,	PUNCT
aiua-11292	122	12	chen	chen	PROPN
aiua-11292	122	13	w.	w.	PROPN
aiua-11292	122	14	urothelial	urothelial	PROPN
aiua-11292	122	15	carcinoma	carcinoma	NOUN
aiua-11292	122	16	associated	associate	VERB
aiua-11292	122	17	1	1	NUM
aiua-11292	122	18	is	be	AUX
aiua-11292	122	19	a	a	DET
aiua-11292	122	20	hypoxia	hypoxia	NOUN
aiua-11292	122	21	-	-	PUNCT
aiua-11292	122	22	inducible	inducible	ADJ
aiua-11292	122	23	factor-1α	factor-1α	NOUN
aiua-11292	122	24	-	-	PUNCT
aiua-11292	122	25	targeted	target	VERB
aiua-11292	122	26	long	long	ADJ
aiua-11292	122	27	noncoding	noncoding	ADJ
aiua-11292	122	28	rna	rna	NOUN
aiua-11292	122	29	that	that	PRON
aiua-11292	122	30	enhances	enhance	VERB
aiua-11292	122	31	hypoxic	hypoxic	ADJ
aiua-11292	122	32	bladder	bladder	NOUN
aiua-11292	122	33	cancer	cancer	NOUN
aiua-11292	122	34	cell	cell	NOUN
aiua-11292	122	35	proliferation	proliferation	NOUN
aiua-11292	122	36	,	,	PUNCT
aiua-11292	122	37	migration	migration	NOUN
aiua-11292	122	38	,	,	PUNCT
aiua-11292	122	39	and	and	CCONJ
aiua-11292	122	40	invasion	invasion	NOUN
aiua-11292	122	41	.	.	PUNCT
aiua-11292	123	1	tumour	tumour	PROPN
aiua-11292	123	2	biol	biol	PROPN
aiua-11292	123	3	.	.	PUNCT
aiua-11292	124	1	2014	2014	NUM
aiua-11292	124	2	;	;	PUNCT
aiua-11292	124	3	35:6901	35:6901	NUM
aiua-11292	124	4	-	-	SYM
aiua-11292	124	5	12	12	NUM
aiua-11292	124	6	.	.	PUNCT
aiua-11292	125	1	7	7	X
aiua-11292	125	2	.	.	NOUN
aiua-11292	125	3	chai	chai	NOUN
aiua-11292	125	4	c	c	PROPN
aiua-11292	125	5	,	,	PUNCT
aiua-11292	125	6	chen	chen	PROPN
aiua-11292	125	7	w	w	PROPN
aiua-11292	125	8	,	,	PUNCT
aiua-11292	125	9	hung	hang	VERB
aiua-11292	125	10	w	w	PROPN
aiua-11292	125	11	,	,	PUNCT
aiua-11292	125	12	et	et	PROPN
aiua-11292	125	13	al	al	PROPN
aiua-11292	125	14	.	.	PROPN
aiua-11292	125	15	hypoxia	hypoxia	NOUN
aiua-11292	125	16	-	-	PUNCT
aiua-11292	125	17	inducible	inducible	ADJ
aiua-11292	125	18	factor-1alpha	factor-1alpha	NOUN
aiua-11292	125	19	expression	expression	NOUN
aiua-11292	125	20	correlates	correlate	VERB
aiua-11292	125	21	with	with	ADP
aiua-11292	125	22	focal	focal	ADJ
aiua-11292	125	23	macrophage	macrophage	ADJ
aiua-11292	125	24	infiltration	infiltration	NOUN
aiua-11292	125	25	,	,	PUNCT
aiua-11292	125	26	angiogenesis	angiogenesis	NOUN
aiua-11292	125	27	and	and	CCONJ
aiua-11292	125	28	unfavourable	unfavourable	ADJ
aiua-11292	125	29	prognosis	prognosis	NOUN
aiua-11292	125	30	in	in	ADP
aiua-11292	125	31	urothelial	urothelial	ADJ
aiua-11292	125	32	carcinoma	carcinoma	NOUN
aiua-11292	125	33	.	.	PUNCT
aiua-11292	126	1	j	j	PROPN
aiua-11292	126	2	clin	clin	PROPN
aiua-11292	126	3	pathol	pathol	PROPN
aiua-11292	126	4	.	.	PUNCT
aiua-11292	126	5	2008	2008	NUM
aiua-11292	126	6	;	;	PUNCT
aiua-11292	126	7	61:658	61:658	NUM
aiua-11292	126	8	-	-	SYM
aiua-11292	126	9	64	64	NUM
aiua-11292	126	10	.	.	NOUN
aiua-11292	127	1	8	8	NUM
aiua-11292	127	2	.	.	X
aiua-11292	128	1	theodoropoulos	theodoropoulos	PROPN
aiua-11292	128	2	ve	ve	PROPN
aiua-11292	128	3	,	,	PUNCT
aiua-11292	128	4	lazaris	lazaris	PROPN
aiua-11292	128	5	ac	ac	PROPN
aiua-11292	128	6	,	,	PUNCT
aiua-11292	128	7	sofras	sofras	PROPN
aiua-11292	128	8	f	f	X
aiua-11292	128	9	,	,	PUNCT
aiua-11292	128	10	et	et	PROPN
aiua-11292	128	11	al	al	PROPN
aiua-11292	128	12	.	.	PROPN
aiua-11292	128	13	hypoxia	hypoxia	NOUN
aiua-11292	128	14	-	-	PUNCT
aiua-11292	128	15	inducible	inducible	ADJ
aiua-11292	128	16	factor	factor	NOUN
aiua-11292	128	17	1	1	NUM
aiua-11292	128	18	alpha	alpha	NOUN
aiua-11292	128	19	expression	expression	NOUN
aiua-11292	128	20	correlates	correlate	VERB
aiua-11292	128	21	with	with	ADP
aiua-11292	128	22	angiogenesis	angiogenesis	NOUN
aiua-11292	128	23	and	and	CCONJ
aiua-11292	128	24	unfavorable	unfavorable	ADJ
aiua-11292	128	25	prognosis	prognosis	NOUN
aiua-11292	128	26	in	in	ADP
aiua-11292	128	27	bladder	bladder	NOUN
aiua-11292	128	28	cancer	cancer	NOUN
aiua-11292	128	29	.	.	PUNCT
aiua-11292	129	1	eur	eur	PROPN
aiua-11292	129	2	urol	urol	PROPN
aiua-11292	129	3	.	.	PUNCT
aiua-11292	130	1	2004	2004	NUM
aiua-11292	130	2	;	;	PUNCT
aiua-11292	130	3	46:200	46:200	NUM
aiua-11292	130	4	-	-	SYM
aiua-11292	130	5	8	8	NUM
aiua-11292	130	6	.	.	NOUN
aiua-11292	130	7	9	9	NUM
aiua-11292	130	8	.	.	PUNCT
aiua-11292	131	1	badr	badr	PROPN
aiua-11292	131	2	s	s	PROPN
aiua-11292	131	3	,	,	PUNCT
aiua-11292	131	4	salem	salem	PROPN
aiua-11292	131	5	a	a	PRON
aiua-11292	131	6	,	,	PUNCT
aiua-11292	131	7	yuosif	yuosif	NOUN
aiua-11292	131	8	ah	ah	INTJ
aiua-11292	131	9	,	,	PUNCT
aiua-11292	131	10	et	et	PROPN
aiua-11292	131	11	al	al	PROPN
aiua-11292	131	12	.	.	PROPN
aiua-11292	131	13	hypoxia	hypoxia	PROPN
aiua-11292	131	14	inducible	inducible	ADJ
aiua-11292	131	15	factor-1alpha	factor-1alpha	NOUN
aiua-11292	131	16	and	and	CCONJ
aiua-11292	131	17	microvessel	microvessel	NOUN
aiua-11292	131	18	density	density	NOUN
aiua-11292	131	19	as	as	ADP
aiua-11292	131	20	angiogenic	angiogenic	ADJ
aiua-11292	131	21	factors	factor	NOUN
aiua-11292	131	22	in	in	ADP
aiua-11292	131	23	bilharzial	bilharzial	ADJ
aiua-11292	131	24	and	and	CCONJ
aiua-11292	131	25	nonbirharzial	nonbirharzial	ADJ
aiua-11292	131	26	bladder	bladder	NOUN
aiua-11292	131	27	cancer	cancer	NOUN
aiua-11292	131	28	.	.	PUNCT
aiua-11292	132	1	clin	clin	PROPN
aiua-11292	132	2	lab	lab	PROPN
aiua-11292	132	3	.	.	PUNCT
aiua-11292	133	1	2013	2013	NUM
aiua-11292	133	2	;	;	PUNCT
aiua-11292	133	3	59:805	59:805	NUM
aiua-11292	133	4	-	-	SYM
aiua-11292	133	5	12	12	NUM
aiua-11292	133	6	.	.	PUNCT
aiua-11292	134	1	10	10	NUM
aiua-11292	134	2	.	.	PUNCT
aiua-11292	135	1	darmadi	darmadi	PROPN
aiua-11292	135	2	d	d	PROPN
aiua-11292	135	3	,	,	PUNCT
aiua-11292	135	4	ruslie	ruslie	PROPN
aiua-11292	135	5	rh	rh	PROPN
aiua-11292	135	6	.	.	PROPN
aiua-11292	135	7	association	association	PROPN
aiua-11292	135	8	between	between	ADP
aiua-11292	135	9	prothrombin	prothrombin	NOUN
aiua-11292	135	10	induced	induce	VERB
aiua-11292	135	11	by	by	ADP
aiua-11292	135	12	vitamin	vitamin	NOUN
aiua-11292	135	13	k	k	PROPN
aiua-11292	135	14	absence	absence	PROPN
aiua-11292	135	15	-	-	PUNCT
aiua-11292	135	16	ii	ii	PROPN
aiua-11292	135	17	(	(	PUNCT
aiua-11292	135	18	pivka	pivka	NOUN
aiua-11292	135	19	-	-	PUNCT
aiua-11292	135	20	ii	ii	NOUN
aiua-11292	135	21	)	)	PUNCT
aiua-11292	135	22	and	and	CCONJ
aiua-11292	135	23	barcelona	barcelona	PROPN
aiua-11292	135	24	clinic	clinic	PROPN
aiua-11292	135	25	liver	liver	NOUN
aiua-11292	135	26	cancer	cancer	NOUN
aiua-11292	135	27	(	(	PUNCT
aiua-11292	135	28	bclc	bclc	ADJ
aiua-11292	135	29	)	)	PUNCT
aiua-11292	135	30	stage	stage	NOUN
aiua-11292	135	31	,	,	PUNCT
aiua-11292	135	32	tumor	tumor	NOUN
aiua-11292	135	33	size	size	NOUN
aiua-11292	135	34	,	,	PUNCT
aiua-11292	135	35	portal	portal	ADJ
aiua-11292	135	36	venous	venous	ADJ
aiua-11292	135	37	thrombosis	thrombosis	NOUN
aiua-11292	135	38	in	in	ADP
aiua-11292	135	39	hepatocellular	hepatocellular	ADJ
aiua-11292	135	40	carcinoma	carcinoma	NOUN
aiua-11292	135	41	patients	patient	NOUN
aiua-11292	135	42	.	.	PUNCT
aiua-11292	136	1	sains	sain	NOUN
aiua-11292	136	2	malays	malays	PROPN
aiua-11292	136	3	.	.	PUNCT
aiua-11292	136	4	2021	2021	NUM
aiua-11292	136	5	;	;	PUNCT
aiua-11292	136	6	50:475	50:475	NUM
aiua-11292	136	7	-	-	SYM
aiua-11292	136	8	80	80	NUM
aiua-11292	136	9	.	.	PUNCT
aiua-11292	136	10	11	11	NUM
aiua-11292	136	11	.	.	PUNCT
aiua-11292	137	1	shigeta	shigeta	PROPN
aiua-11292	137	2	k	k	PROPN
aiua-11292	137	3	,	,	PUNCT
aiua-11292	137	4	hasegawa	hasegawa	PROPN
aiua-11292	137	5	m	m	PROPN
aiua-11292	137	6	,	,	PUNCT
aiua-11292	137	7	hishiki	hishiki	PROPN
aiua-11292	137	8	t	t	PROPN
aiua-11292	137	9	,	,	PUNCT
aiua-11292	137	10	et	et	PROPN
aiua-11292	137	11	al	al	PROPN
aiua-11292	137	12	.	.	PROPN
aiua-11292	137	13	idh2	idh2	PROPN
aiua-11292	137	14	stabilizes	stabilize	VERB
aiua-11292	137	15	hif1α	hif1α	ADV
aiua-11292	137	16	-	-	PUNCT
aiua-11292	137	17	induced	induce	VERB
aiua-11292	137	18	metabolic	metabolic	NOUN
aiua-11292	137	19	reprogramming	reprogramme	VERB
aiua-11292	137	20	and	and	CCONJ
aiua-11292	137	21	promotes	promote	VERB
aiua-11292	137	22	chemoresistance	chemoresistance	NOUN
aiua-11292	137	23	in	in	ADP
aiua-11292	137	24	urothelial	urothelial	ADJ
aiua-11292	137	25	cancer	cancer	NOUN
aiua-11292	137	26	.	.	PUNCT
aiua-11292	138	1	embo	embo	PROPN
aiua-11292	138	2	j.	j.	PROPN
aiua-11292	138	3	2023	2023	NUM
aiua-11292	138	4	;	;	PUNCT
aiua-11292	138	5	42	42	NUM
aiua-11292	138	6	:	:	PUNCT
aiua-11292	138	7	e110620	e110620	NOUN
aiua-11292	138	8	.	.	PROPN
aiua-11292	139	1	12	12	NUM
aiua-11292	139	2	.	.	PUNCT
aiua-11292	140	1	darmadi	darmadi	PROPN
aiua-11292	140	2	d	d	PROPN
aiua-11292	140	3	,	,	PUNCT
aiua-11292	140	4	ruslie	ruslie	PROPN
aiua-11292	140	5	rh	rh	PROPN
aiua-11292	140	6	,	,	PUNCT
aiua-11292	140	7	pakpahan	pakpahan	PROPN
aiua-11292	140	8	c.	c.	NOUN
aiua-11292	140	9	vascular	vascular	ADJ
aiua-11292	140	10	endothelial	endothelial	ADJ
aiua-11292	140	11	growth	growth	NOUN
aiua-11292	140	12	factor	factor	NOUN
aiua-11292	140	13	levels	level	NOUN
aiua-11292	140	14	difference	difference	NOUN
aiua-11292	140	15	among	among	ADP
aiua-11292	140	16	hepatocellular	hepatocellular	ADJ
aiua-11292	140	17	cancer	cancer	NOUN
aiua-11292	140	18	patients	patient	NOUN
aiua-11292	140	19	based	base	VERB
aiua-11292	140	20	on	on	ADP
aiua-11292	140	21	barcelona	barcelona	PROPN
aiua-11292	140	22	clinic	clinic	PROPN
aiua-11292	140	23	liver	liver	NOUN
aiua-11292	140	24	cancer	cancer	NOUN
aiua-11292	140	25	staging	staging	NOUN
aiua-11292	140	26	.	.	PUNCT
aiua-11292	141	1	open	open	ADJ
aiua-11292	141	2	access	access	NOUN
aiua-11292	141	3	maced	mace	VERB
aiua-11292	141	4	j	j	PROPN
aiua-11292	141	5	med	med	PROPN
aiua-11292	141	6	sci	sci	PROPN
aiua-11292	141	7	.	.	PROPN
aiua-11292	141	8	2021	2021	NUM
aiua-11292	141	9	;	;	PUNCT
aiua-11292	141	10	9:797	9:797	NUM
aiua-11292	141	11	-	-	SYM
aiua-11292	141	12	800	800	NUM
aiua-11292	141	13	.	.	NOUN
aiua-11292	141	14	13	13	NUM
aiua-11292	141	15	.	.	PUNCT
aiua-11292	142	1	ruslie	ruslie	PROPN
aiua-11292	142	2	rh	rh	PROPN
aiua-11292	142	3	,	,	PUNCT
aiua-11292	142	4	darmadi	darmadi	NOUN
aiua-11292	142	5	d	d	PROPN
aiua-11292	142	6	,	,	PUNCT
aiua-11292	142	7	siregar	siregar	PROPN
aiua-11292	142	8	ga	ga	PROPN
aiua-11292	142	9	.	.	PROPN
aiua-11292	142	10	vascular	vascular	ADJ
aiua-11292	142	11	endothelial	endothelial	ADJ
aiua-11292	142	12	growth	growth	NOUN
aiua-11292	142	13	factor	factor	NOUN
aiua-11292	142	14	(	(	PUNCT
aiua-11292	142	15	vegf	vegf	PROPN
aiua-11292	142	16	)	)	PUNCT
aiua-11292	142	17	and	and	CCONJ
aiua-11292	142	18	neopterin	neopterin	NOUN
aiua-11292	142	19	levels	level	NOUN
aiua-11292	142	20	in	in	ADP
aiua-11292	142	21	children	child	NOUN
aiua-11292	142	22	with	with	ADP
aiua-11292	142	23	steroid	steroid	NOUN
aiua-11292	142	24	sensitive	sensitive	ADJ
aiua-11292	142	25	and	and	CCONJ
aiua-11292	142	26	steroid	steroid	NOUN
aiua-11292	142	27	-	-	PUNCT
aiua-11292	142	28	resistant	resistant	ADJ
aiua-11292	142	29	nephrotic	nephrotic	ADJ
aiua-11292	142	30	syndrome	syndrome	NOUN
aiua-11292	142	31	.	.	PUNCT
aiua-11292	143	1	med	med	PROPN
aiua-11292	143	2	arch	arch	NOUN
aiua-11292	143	3	.	.	PUNCT
aiua-11292	144	1	2021	2021	NUM
aiua-11292	144	2	;	;	PUNCT
aiua-11292	144	3	75:133	75:133	NUM
aiua-11292	144	4	-	-	SYM
aiua-11292	144	5	7	7	NUM
aiua-11292	144	6	.	.	NOUN
aiua-11292	144	7	14	14	NUM
aiua-11292	144	8	.	.	PUNCT
aiua-11292	145	1	deniz	deniz	PROPN
aiua-11292	145	2	h	h	PROPN
aiua-11292	145	3	,	,	PUNCT
aiua-11292	145	4	karakok	karakok	PROPN
aiua-11292	145	5	m	m	PROPN
aiua-11292	145	6	,	,	PUNCT
aiua-11292	145	7	yagci	yagci	PROPN
aiua-11292	145	8	f	f	X
aiua-11292	145	9	,	,	PUNCT
aiua-11292	145	10	guldur	guldur	VERB
aiua-11292	145	11	me	i	PRON
aiua-11292	145	12	.	.	PUNCT
aiua-11292	146	1	evaluation	evaluation	NOUN
aiua-11292	146	2	of	of	ADP
aiua-11292	146	3	relationship	relationship	NOUN
aiua-11292	146	4	between	between	ADP
aiua-11292	146	5	hif-1α	hif-1α	NOUN
aiua-11292	146	6	immunoreactivity	immunoreactivity	NOUN
aiua-11292	146	7	and	and	CCONJ
aiua-11292	146	8	stage	stage	NOUN
aiua-11292	146	9	,	,	PUNCT
aiua-11292	146	10	grade	grade	NOUN
aiua-11292	146	11	,	,	PUNCT
aiua-11292	146	12	angiogenic	angiogenic	ADJ
aiua-11292	146	13	profile	profile	NOUN
aiua-11292	146	14	and	and	CCONJ
aiua-11292	146	15	proliferative	proliferative	ADJ
aiua-11292	146	16	index	index	NOUN
aiua-11292	146	17	in	in	ADP
aiua-11292	146	18	bladder	bladder	NOUN
aiua-11292	146	19	urothelial	urothelial	ADJ
aiua-11292	146	20	carcinomas	carcinoma	NOUN
aiua-11292	146	21	.	.	PUNCT
aiua-11292	147	1	int	int	NOUN
aiua-11292	147	2	urol	urol	ADJ
aiua-11292	147	3	nephrol	nephrol	NOUN
aiua-11292	147	4	.	.	PUNCT
aiua-11292	148	1	2010	2010	NUM
aiua-11292	148	2	;	;	PUNCT
aiua-11292	148	3	42:103	42:103	NUM
aiua-11292	148	4	-	-	SYM
aiua-11292	148	5	7	7	NUM
aiua-11292	148	6	.	.	PUNCT
aiua-11292	149	1	correspondence	correspondence	NOUN
aiua-11292	149	2	ginanda	ginanda	PROPN
aiua-11292	149	3	putra	putra	PROPN
aiua-11292	149	4	siregar	siregar	NOUN
aiua-11292	149	5	,	,	PUNCT
aiua-11292	149	6	md	md	PROPN
aiua-11292	149	7	(	(	PUNCT
aiua-11292	149	8	corresponding	correspond	VERB
aiua-11292	149	9	author	author	NOUN
aiua-11292	149	10	)	)	PUNCT
aiua-11292	149	11	ginandasir@gmail.com	ginandasir@gmail.com	X
aiua-11292	150	1	doctoral	doctoral	ADJ
aiua-11292	150	2	study	study	NOUN
aiua-11292	150	3	program	program	NOUN
aiua-11292	150	4	,	,	PUNCT
aiua-11292	150	5	faculty	faculty	NOUN
aiua-11292	150	6	of	of	ADP
aiua-11292	150	7	medicine	medicine	NOUN
aiua-11292	150	8	,	,	PUNCT
aiua-11292	150	9	universitas	universita	NOUN
aiua-11292	150	10	padjadjaran	padjadjaran	NOUN
aiua-11292	150	11	,	,	PUNCT
aiua-11292	150	12	bandung	bandung	PROPN
aiua-11292	150	13	,	,	PUNCT
aiua-11292	150	14	indonesia	indonesia	PROPN
aiua-11292	150	15	and	and	CCONJ
aiua-11292	150	16	division	division	NOUN
aiua-11292	150	17	of	of	ADP
aiua-11292	150	18	urology	urology	NOUN
aiua-11292	150	19	,	,	PUNCT
aiua-11292	150	20	department	department	NOUN
aiua-11292	150	21	of	of	ADP
aiua-11292	150	22	surgery	surgery	NOUN
aiua-11292	150	23	,	,	PUNCT
aiua-11292	150	24	faculty	faculty	NOUN
aiua-11292	150	25	of	of	ADP
aiua-11292	150	26	medicine	medicine	NOUN
aiua-11292	150	27	,	,	PUNCT
aiua-11292	150	28	universitas	universita	NOUN
aiua-11292	150	29	sumatera	sumatera	NOUN
aiua-11292	150	30	utara	utara	NOUN
aiua-11292	150	31	,	,	PUNCT
aiua-11292	150	32	medan	medan	PROPN
aiua-11292	150	33	,	,	PUNCT
aiua-11292	150	34	indonesia	indonesia	PROPN
aiua-11292	150	35	ida	ida	PROPN
aiua-11292	150	36	parwati	parwati	PROPN
aiua-11292	150	37	,	,	PUNCT
aiua-11292	150	38	md	md	PROPN
aiua-11292	150	39	department	department	PROPN
aiua-11292	150	40	of	of	ADP
aiua-11292	150	41	clinical	clinical	ADJ
aiua-11292	150	42	pathology	pathology	NOUN
aiua-11292	150	43	,	,	PUNCT
aiua-11292	150	44	faculty	faculty	NOUN
aiua-11292	150	45	of	of	ADP
aiua-11292	150	46	medicine	medicine	NOUN
aiua-11292	150	47	,	,	PUNCT
aiua-11292	150	48	universitas	universita	NOUN
aiua-11292	150	49	padjadjaran	padjadjaran	NOUN
aiua-11292	150	50	,	,	PUNCT
aiua-11292	150	51	bandung	bandung	PROPN
aiua-11292	150	52	,	,	PUNCT
aiua-11292	150	53	indonesia	indonesia	PROPN
aiua-11292	150	54	bambang	bambang	PROPN
aiua-11292	150	55	sasongko	sasongko	VERB
aiua-11292	150	56	noegroho	noegroho	PROPN
aiua-11292	150	57	,	,	PUNCT
aiua-11292	150	58	md	md	PROPN
aiua-11292	150	59	ferry	ferry	PROPN
aiua-11292	150	60	safridai	safridai	PROPN
aiua-11292	150	61	,	,	PUNCT
aiua-11292	150	62	md	md	PROPN
aiua-11292	150	63	department	department	PROPN
aiua-11292	150	64	of	of	ADP
aiua-11292	150	65	urology	urology	NOUN
aiua-11292	150	66	,	,	PUNCT
aiua-11292	150	67	faculty	faculty	NOUN
aiua-11292	150	68	of	of	ADP
aiua-11292	150	69	medicine	medicine	NOUN
aiua-11292	150	70	,	,	PUNCT
aiua-11292	150	71	universitas	universita	NOUN
aiua-11292	150	72	padjadjaran	padjadjaran	NOUN
aiua-11292	150	73	,	,	PUNCT
aiua-11292	150	74	bandung	bandung	PROPN
aiua-11292	150	75	,	,	PUNCT
aiua-11292	150	76	indonesia	indonesia	PROPN
aiua-11292	150	77	gerhard	gerhard	PROPN
aiua-11292	150	78	reinaldi	reinaldi	PROPN
aiua-11292	150	79	situmorang	situmorang	PROPN
aiua-11292	150	80	,	,	PUNCT
aiua-11292	150	81	md	md	PROPN
aiua-11292	150	82	department	department	PROPN
aiua-11292	150	83	of	of	ADP
aiua-11292	150	84	urology	urology	NOUN
aiua-11292	150	85	,	,	PUNCT
aiua-11292	150	86	faculty	faculty	NOUN
aiua-11292	150	87	of	of	ADP
aiua-11292	150	88	medicine	medicine	NOUN
aiua-11292	150	89	,	,	PUNCT
aiua-11292	150	90	universitas	universitas	PROPN
aiua-11292	150	91	indonesia	indonesia	PROPN
aiua-11292	150	92	,	,	PUNCT
aiua-11292	150	93	jakarta	jakarta	PROPN
aiua-11292	150	94	,	,	PUNCT
aiua-11292	150	95	indonesia	indonesia	PROPN
aiua-11292	150	96	raden	raden	VERB
aiua-11292	150	97	yohana	yohana	PROPN
aiua-11292	150	98	,	,	PUNCT
aiua-11292	150	99	md	md	PROPN
aiua-11292	150	100	division	division	NOUN
aiua-11292	150	101	of	of	ADP
aiua-11292	150	102	oncology	oncology	NOUN
aiua-11292	150	103	,	,	PUNCT
aiua-11292	150	104	department	department	NOUN
aiua-11292	150	105	of	of	ADP
aiua-11292	150	106	surgery	surgery	NOUN
aiua-11292	150	107	,	,	PUNCT
aiua-11292	150	108	faculty	faculty	NOUN
aiua-11292	150	109	of	of	ADP
aiua-11292	150	110	medicine	medicine	NOUN
aiua-11292	150	111	,	,	PUNCT
aiua-11292	150	112	padjadjaran	padjadjaran	NOUN
aiua-11292	150	113	university	university	PROPN
aiua-11292	150	114	,	,	PUNCT
aiua-11292	150	115	bandung	bandung	PROPN
aiua-11292	150	116	,	,	PUNCT
aiua-11292	150	117	indonesia	indonesia	PROPN
aiua-11292	150	118	astrid	astrid	PROPN
aiua-11292	150	119	feinisa	feinisa	PROPN
aiua-11292	150	120	khairani	khairani	PROPN
aiua-11292	150	121	,	,	PUNCT
aiua-11292	150	122	md	md	PROPN
aiua-11292	150	123	department	department	PROPN
aiua-11292	150	124	of	of	ADP
aiua-11292	150	125	biomedical	biomedical	ADJ
aiua-11292	150	126	sciences	science	NOUN
aiua-11292	150	127	,	,	PUNCT
aiua-11292	150	128	faculty	faculty	NOUN
aiua-11292	150	129	of	of	ADP
aiua-11292	150	130	medicine	medicine	NOUN
aiua-11292	150	131	,	,	PUNCT
aiua-11292	150	132	universitas	universita	NOUN
aiua-11292	150	133	padjadjaran	padjadjaran	NOUN
aiua-11292	150	134	,	,	PUNCT
aiua-11292	150	135	bandung	bandung	PROPN
aiua-11292	150	136	,	,	PUNCT
aiua-11292	150	137	indonesia	indonesia	PROPN
aiua-11292	150	138	conflict	conflict	NOUN
aiua-11292	150	139	of	of	ADP
aiua-11292	150	140	interest	interest	NOUN
aiua-11292	150	141	:	:	PUNCT
aiua-11292	150	142	the	the	DET
aiua-11292	150	143	authors	author	NOUN
aiua-11292	150	144	declare	declare	VERB
aiua-11292	150	145	no	no	DET
aiua-11292	150	146	potential	potential	ADJ
aiua-11292	150	147	conflict	conflict	NOUN
aiua-11292	150	148	of	of	ADP
aiua-11292	150	149	interest	interest	NOUN
aiua-11292	150	150	.	.	PUNCT