id	sid	tid	token	lemma	pos
aiua-13635	1	1	stesura	stesura	PROPN
aiua-13635	1	2	seveso	seveso	PROPN
aiua-13635	1	3	archivio	archivio	PROPN
aiua-13635	1	4	italiano	italiano	X
aiua-13635	1	5	di	di	X
aiua-13635	1	6	urologia	urologia	PROPN
aiua-13635	1	7	e	e	PROPN
aiua-13635	1	8	andrologia	andrologia	NOUN
aiua-13635	1	9	2025	2025	NUM
aiua-13635	1	10	;	;	PUNCT
aiua-13635	1	11	97(2):13635	97(2):13635	NUM
aiua-13635	1	12	1	1	NUM
aiua-13635	1	13	original	original	ADJ
aiua-13635	1	14	paper	paper	NOUN
aiua-13635	1	15	introduction	introduction	NOUN
aiua-13635	1	16	breast	breast	NOUN
aiua-13635	1	17	cancer	cancer	NOUN
aiua-13635	1	18	(	(	PUNCT
aiua-13635	1	19	brca	brca	PROPN
aiua-13635	1	20	)	)	PUNCT
aiua-13635	1	21	gene	gene	NOUN
aiua-13635	1	22	mutations	mutation	NOUN
aiua-13635	1	23	are	be	AUX
aiua-13635	1	24	known	know	VERB
aiua-13635	1	25	to	to	PART
aiua-13635	1	26	be	be	AUX
aiua-13635	1	27	associated	associate	VERB
aiua-13635	1	28	with	with	ADP
aiua-13635	1	29	earlier	early	ADJ
aiua-13635	1	30	-	-	PUNCT
aiua-13635	1	31	onset	onset	VERB
aiua-13635	1	32	and	and	CCONJ
aiua-13635	1	33	clinically	clinically	ADV
aiua-13635	1	34	significant	significant	ADJ
aiua-13635	1	35	prostate	prostate	NOUN
aiua-13635	1	36	cancer	cancer	NOUN
aiua-13635	1	37	(	(	PUNCT
aiua-13635	1	38	capca	capca	PROPN
aiua-13635	1	39	)	)	PUNCT
aiua-13635	1	40	(	(	PUNCT
aiua-13635	1	41	1	1	NUM
aiua-13635	1	42	)	)	PUNCT
aiua-13635	1	43	.	.	PUNCT
aiua-13635	2	1	brca1	brca1	PROPN
aiua-13635	2	2	and	and	CCONJ
aiua-13635	2	3	brca2	brca2	PROPN
aiua-13635	2	4	are	be	AUX
aiua-13635	2	5	tumour	tumour	ADJ
aiua-13635	2	6	suppressor	suppressor	NOUN
aiua-13635	2	7	genes	gene	NOUN
aiua-13635	2	8	:	:	PUNCT
aiua-13635	3	1	brca1	brca1	PROPN
aiua-13635	3	2	wild	wild	ADJ
aiua-13635	3	3	-	-	PUNCT
aiua-13635	3	4	type	type	NOUN
aiua-13635	3	5	controls	control	NOUN
aiua-13635	3	6	cell	cell	NOUN
aiua-13635	3	7	cycle	cycle	NOUN
aiua-13635	3	8	checkpoints	checkpoint	NOUN
aiua-13635	3	9	and	and	CCONJ
aiua-13635	3	10	repairs	repair	VERB
aiua-13635	3	11	dna	dna	PROPN
aiua-13635	3	12	in	in	ADP
aiua-13635	3	13	a	a	DET
aiua-13635	3	14	normal	normal	ADJ
aiua-13635	3	15	cell	cell	NOUN
aiua-13635	3	16	(	(	PUNCT
aiua-13635	3	17	2	2	NUM
aiua-13635	3	18	)	)	PUNCT
aiua-13635	3	19	;	;	PUNCT
aiua-13635	3	20	brca2	brca2	PROPN
aiua-13635	3	21	is	be	AUX
aiua-13635	3	22	a	a	DET
aiua-13635	3	23	large	large	ADJ
aiua-13635	3	24	protein	protein	NOUN
aiua-13635	3	25	consisting	consist	VERB
aiua-13635	3	26	of	of	ADP
aiua-13635	3	27	27	27	NUM
aiua-13635	3	28	exons	exon	NOUN
aiua-13635	3	29	and	and	CCONJ
aiua-13635	3	30	may	may	AUX
aiua-13635	3	31	play	play	VERB
aiua-13635	3	32	a	a	DET
aiua-13635	3	33	role	role	NOUN
aiua-13635	3	34	in	in	ADP
aiua-13635	3	35	regulating	regulate	VERB
aiua-13635	3	36	transcription	transcription	NOUN
aiua-13635	3	37	and	and	CCONJ
aiua-13635	3	38	is	be	AUX
aiua-13635	3	39	involved	involve	VERB
aiua-13635	3	40	in	in	ADP
aiua-13635	3	41	dna	dna	PROPN
aiua-13635	3	42	repair	repair	NOUN
aiua-13635	3	43	to	to	PART
aiua-13635	3	44	maintain	maintain	VERB
aiua-13635	3	45	genome	genome	NOUN
aiua-13635	3	46	integrity	integrity	NOUN
aiua-13635	3	47	during	during	ADP
aiua-13635	3	48	replication	replication	NOUN
aiua-13635	3	49	(	(	PUNCT
aiua-13635	3	50	3	3	NUM
aiua-13635	3	51	)	)	PUNCT
aiua-13635	3	52	.	.	PUNCT
aiua-13635	4	1	many	many	ADJ
aiua-13635	4	2	retrospective	retrospective	ADJ
aiua-13635	4	3	studies	study	NOUN
aiua-13635	4	4	have	have	AUX
aiua-13635	4	5	reported	report	VERB
aiua-13635	4	6	higher	high	ADJ
aiua-13635	4	7	rates	rate	NOUN
aiua-13635	4	8	of	of	ADP
aiua-13635	4	9	lymph	lymph	NOUN
aiua-13635	4	10	node	node	NOUN
aiua-13635	4	11	involvement	involvement	NOUN
aiua-13635	4	12	,	,	PUNCT
aiua-13635	4	13	distant	distant	ADJ
aiua-13635	4	14	metastases	metastasis	NOUN
aiua-13635	4	15	at	at	ADP
aiua-13635	4	16	diagnosis	diagnosis	NOUN
aiua-13635	4	17	and	and	CCONJ
aiua-13635	4	18	a	a	DET
aiua-13635	4	19	higher	high	ADJ
aiua-13635	4	20	mortality	mortality	NOUN
aiua-13635	4	21	rate	rate	NOUN
aiua-13635	4	22	in	in	ADP
aiua-13635	4	23	pca	pca	NOUN
aiua-13635	4	24	mutation	mutation	NOUN
aiua-13635	4	25	carriers	carrier	NOUN
aiua-13635	4	26	.	.	PUNCT
aiua-13635	5	1	germline	germline	NOUN
aiua-13635	5	2	brca2	brca2	PROPN
aiua-13635	5	3	mutation	mutation	NOUN
aiua-13635	5	4	status	status	NOUN
aiua-13635	5	5	is	be	AUX
aiua-13635	5	6	considered	consider	VERB
aiua-13635	5	7	an	an	DET
aiua-13635	5	8	independent	independent	ADJ
aiua-13635	5	9	prognostic	prognostic	ADJ
aiua-13635	5	10	factor	factor	NOUN
aiua-13635	5	11	for	for	ADP
aiua-13635	5	12	poorer	poor	ADJ
aiua-13635	5	13	outcome	outcome	NOUN
aiua-13635	5	14	(	(	PUNCT
aiua-13635	5	15	4	4	NUM
aiua-13635	5	16	)	)	PUNCT
aiua-13635	5	17	.	.	PUNCT
aiua-13635	6	1	in	in	ADP
aiua-13635	6	2	addition	addition	NOUN
aiua-13635	6	3	,	,	PUNCT
aiua-13635	6	4	brca2	brca2	NOUN
aiua-13635	6	5	mutation	mutation	NOUN
aiua-13635	6	6	in	in	ADP
aiua-13635	6	7	men	man	NOUN
aiua-13635	6	8	with	with	ADP
aiua-13635	6	9	organ	organ	NOUN
aiua-13635	6	10	-	-	PUNCT
aiua-13635	6	11	confined	confine	VERB
aiua-13635	6	12	pca	pca	NOUN
aiua-13635	6	13	exhibits	exhibit	VERB
aiua-13635	6	14	genomic	genomic	ADJ
aiua-13635	6	15	instability	instability	NOUN
aiua-13635	6	16	typically	typically	ADV
aiua-13635	6	17	seen	see	VERB
aiua-13635	6	18	in	in	ADP
aiua-13635	6	19	metastatic	metastatic	ADJ
aiua-13635	6	20	castration	castration	NOUN
aiua-13635	6	21	-	-	PUNCT
aiua-13635	6	22	resistant	resistant	ADJ
aiua-13635	6	23	cancer	cancer	NOUN
aiua-13635	6	24	(	(	PUNCT
aiua-13635	6	25	5	5	NUM
aiua-13635	6	26	)	)	PUNCT
aiua-13635	6	27	,	,	PUNCT
aiua-13635	6	28	suggesting	suggest	VERB
aiua-13635	6	29	a	a	DET
aiua-13635	6	30	poor	poor	ADJ
aiua-13635	6	31	longterm	longterm	NOUN
aiua-13635	6	32	prognosis	prognosis	NOUN
aiua-13635	6	33	.	.	PUNCT
aiua-13635	7	1	in	in	ADP
aiua-13635	7	2	clinical	clinical	ADJ
aiua-13635	7	3	practice	practice	NOUN
aiua-13635	7	4	,	,	PUNCT
aiua-13635	7	5	screening	screen	VERB
aiua-13635	7	6	protocols	protocol	NOUN
aiua-13635	7	7	for	for	ADP
aiua-13635	7	8	the	the	DET
aiua-13635	7	9	early	early	ADJ
aiua-13635	7	10	diagnosis	diagnosis	NOUN
aiua-13635	7	11	of	of	ADP
aiua-13635	7	12	pca	pca	NOUN
aiua-13635	7	13	are	be	AUX
aiua-13635	7	14	based	base	VERB
aiua-13635	7	15	on	on	ADP
aiua-13635	7	16	the	the	DET
aiua-13635	7	17	determination	determination	NOUN
aiua-13635	7	18	of	of	ADP
aiua-13635	7	19	prostate	prostate	NOUN
aiua-13635	7	20	specific	specific	ADJ
aiua-13635	7	21	antigen	antigen	NOUN
aiua-13635	7	22	(	(	PUNCT
aiua-13635	7	23	psa	psa	NOUN
aiua-13635	7	24	)	)	PUNCT
aiua-13635	7	25	.	.	PUNCT
aiua-13635	8	1	to	to	PART
aiua-13635	8	2	improve	improve	VERB
aiua-13635	8	3	accuracy	accuracy	NOUN
aiua-13635	8	4	,	,	PUNCT
aiua-13635	8	5	other	other	ADJ
aiua-13635	8	6	biological	biological	ADJ
aiua-13635	8	7	markers	marker	NOUN
aiua-13635	8	8	(	(	PUNCT
aiua-13635	8	9	6	6	NUM
aiua-13635	8	10	-	-	SYM
aiua-13635	8	11	8)	8)	NUM
aiua-13635	8	12	,	,	PUNCT
aiua-13635	8	13	risk	risk	NOUN
aiua-13635	8	14	calculators	calculator	NOUN
aiua-13635	8	15	(	(	PUNCT
aiua-13635	8	16	9	9	NUM
aiua-13635	8	17	)	)	PUNCT
aiua-13635	8	18	,	,	PUNCT
aiua-13635	8	19	magnetic	magnetic	ADJ
aiua-13635	8	20	resonance	resonance	NOUN
aiua-13635	8	21	imaging	imaging	NOUN
aiua-13635	8	22	(	(	PUNCT
aiua-13635	8	23	mri	mri	NOUN
aiua-13635	8	24	)	)	PUNCT
aiua-13635	8	25	(	(	PUNCT
aiua-13635	8	26	10	10	NUM
aiua-13635	8	27	)	)	PUNCT
aiua-13635	8	28	and	and	CCONJ
aiua-13635	8	29	genetic	genetic	ADJ
aiua-13635	8	30	markers	marker	NOUN
aiua-13635	8	31	(	(	PUNCT
aiua-13635	8	32	11	11	NUM
aiua-13635	8	33	-	-	SYM
aiua-13635	8	34	13	13	NUM
aiua-13635	8	35	)	)	PUNCT
aiua-13635	8	36	have	have	AUX
aiua-13635	8	37	recently	recently	ADV
aiua-13635	8	38	been	be	AUX
aiua-13635	8	39	introduced	introduce	VERB
aiua-13635	8	40	.	.	PUNCT
aiua-13635	9	1	recently	recently	ADV
aiua-13635	9	2	,	,	PUNCT
aiua-13635	9	3	the	the	DET
aiua-13635	9	4	impact	impact	NOUN
aiua-13635	9	5	study	study	NOUN
aiua-13635	9	6	(	(	PUNCT
aiua-13635	9	7	identification	identification	NOUN
aiua-13635	9	8	of	of	ADP
aiua-13635	9	9	men	man	NOUN
aiua-13635	9	10	with	with	ADP
aiua-13635	9	11	a	a	DET
aiua-13635	9	12	genetic	genetic	ADJ
aiua-13635	9	13	predisposition	predisposition	NOUN
aiua-13635	9	14	to	to	ADP
aiua-13635	9	15	prostate	prostate	NOUN
aiua-13635	9	16	cancer	cancer	NOUN
aiua-13635	9	17	:	:	PUNCT
aiua-13635	9	18	targeted	target	VERB
aiua-13635	9	19	screening	screening	NOUN
aiua-13635	9	20	in	in	ADP
aiua-13635	9	21	men	man	NOUN
aiua-13635	9	22	at	at	ADP
aiua-13635	9	23	higher	high	ADJ
aiua-13635	9	24	genetic	genetic	ADJ
aiua-13635	9	25	risk	risk	NOUN
aiua-13635	9	26	and	and	CCONJ
aiua-13635	9	27	controls	control	NOUN
aiua-13635	9	28	)	)	PUNCT
aiua-13635	9	29	an	an	DET
aiua-13635	9	30	international	international	ADJ
aiua-13635	9	31	and	and	CCONJ
aiua-13635	9	32	multicentre	multicentre	NOUN
aiua-13635	9	33	study	study	NOUN
aiua-13635	9	34	,	,	PUNCT
aiua-13635	9	35	evaluated	evaluate	VERB
aiua-13635	9	36	targeted	target	VERB
aiua-13635	9	37	pca	pca	NOUN
aiua-13635	9	38	screening	screening	NOUN
aiua-13635	9	39	in	in	ADP
aiua-13635	9	40	men	man	NOUN
aiua-13635	9	41	with	with	ADP
aiua-13635	9	42	germline	germline	NOUN
aiua-13635	9	43	brca1/2	brca1/2	ADJ
aiua-13635	9	44	mutations	mutation	NOUN
aiua-13635	9	45	(	(	PUNCT
aiua-13635	9	46	13	13	NUM
aiua-13635	9	47	)	)	PUNCT
aiua-13635	9	48	.	.	PUNCT
aiua-13635	10	1	in	in	ADP
aiua-13635	10	2	this	this	DET
aiua-13635	10	3	study	study	NOUN
aiua-13635	10	4	,	,	PUNCT
aiua-13635	10	5	we	we	PRON
aiua-13635	10	6	report	report	VERB
aiua-13635	10	7	on	on	ADP
aiua-13635	10	8	brca1/2	brca1/2	ADJ
aiua-13635	10	9	evaluation	evaluation	NOUN
aiua-13635	10	10	in	in	ADP
aiua-13635	10	11	men	man	NOUN
aiua-13635	10	12	with	with	ADP
aiua-13635	10	13	high	high	ADJ
aiua-13635	10	14	risk	risk	NOUN
aiua-13635	10	15	pca	pca	NOUN
aiua-13635	10	16	,	,	PUNCT
aiua-13635	10	17	including	include	VERB
aiua-13635	10	18	the	the	DET
aiua-13635	10	19	oncological	oncological	ADJ
aiua-13635	10	20	consequences	consequence	NOUN
aiua-13635	10	21	for	for	ADP
aiua-13635	10	22	the	the	DET
aiua-13635	10	23	patient	patient	NOUN
aiua-13635	10	24	and	and	CCONJ
aiua-13635	10	25	family	family	NOUN
aiua-13635	10	26	members	member	NOUN
aiua-13635	10	27	.	.	PUNCT
aiua-13635	11	1	materials	material	NOUN
aiua-13635	11	2	and	and	CCONJ
aiua-13635	11	3	methods	method	NOUN
aiua-13635	11	4	from	from	ADP
aiua-13635	11	5	january	january	PROPN
aiua-13635	11	6	2023	2023	NUM
aiua-13635	11	7	to	to	ADP
aiua-13635	11	8	december	december	PROPN
aiua-13635	11	9	2024	2024	NUM
aiua-13635	11	10	,	,	PUNCT
aiua-13635	11	11	52	52	NUM
aiua-13635	11	12	men	man	NOUN
aiua-13635	11	13	(	(	PUNCT
aiua-13635	11	14	median	median	ADJ
aiua-13635	11	15	age	age	NOUN
aiua-13635	11	16	73	73	NUM
aiua-13635	11	17	years	year	NOUN
aiua-13635	11	18	;	;	PUNCT
aiua-13635	11	19	range	range	NOUN
aiua-13635	11	20	:	:	PUNCT
aiua-13635	11	21	52	52	NUM
aiua-13635	11	22	-	-	SYM
aiua-13635	11	23	84	84	NUM
aiua-13635	11	24	)	)	PUNCT
aiua-13635	11	25	with	with	ADP
aiua-13635	11	26	confirmed	confirm	VERB
aiua-13635	11	27	pca	pca	NOUN
aiua-13635	11	28	diagnosis	diagnosis	NOUN
aiua-13635	11	29	underwent	underwent	NOUN
aiua-13635	11	30	somatic	somatic	ADJ
aiua-13635	11	31	and	and	CCONJ
aiua-13635	11	32	germline	germline	PROPN
aiua-13635	11	33	brca1	brca1	PROPN
aiua-13635	11	34	and	and	CCONJ
aiua-13635	11	35	brca2	brca2	PROPN
aiua-13635	11	36	assessment	assessment	NOUN
aiua-13635	11	37	;	;	PUNCT
aiua-13635	11	38	11/52	11/52	NUM
aiua-13635	11	39	(	(	PUNCT
aiua-13635	11	40	21	21	NUM
aiua-13635	11	41	%	%	NOUN
aiua-13635	11	42	)	)	PUNCT
aiua-13635	11	43	patients	patient	NOUN
aiua-13635	11	44	documented	document	VERB
aiua-13635	11	45	a	a	DET
aiua-13635	11	46	family	family	NOUN
aiua-13635	11	47	history	history	NOUN
aiua-13635	11	48	of	of	ADP
aiua-13635	11	49	cancer	cancer	NOUN
aiua-13635	11	50	.	.	PUNCT
aiua-13635	12	1	patients	patient	NOUN
aiua-13635	12	2	were	be	AUX
aiua-13635	12	3	at	at	ADP
aiua-13635	12	4	different	different	ADJ
aiua-13635	12	5	clinical	clinical	ADJ
aiua-13635	12	6	stages	stage	NOUN
aiua-13635	12	7	:	:	PUNCT
aiua-13635	12	8	high	high	ADJ
aiua-13635	12	9	-	-	PUNCT
aiua-13635	12	10	grade	grade	NOUN
aiua-13635	12	11	(	(	PUNCT
aiua-13635	12	12	71	71	NUM
aiua-13635	12	13	%	%	NOUN
aiua-13635	12	14	had	have	VERB
aiua-13635	12	15	a	a	DET
aiua-13635	12	16	gleason	gleason	PROPN
aiua-13635	12	17	score	score	NOUN
aiua-13635	12	18	>	>	X
aiua-13635	12	19	8)	8)	NUM
aiua-13635	12	20	(	(	PUNCT
aiua-13635	12	21	14,15	14,15	NUM
aiua-13635	12	22	)	)	PUNCT
aiua-13635	12	23	,	,	PUNCT
aiua-13635	12	24	locally	locally	ADV
aiua-13635	12	25	advanced	advanced	ADJ
aiua-13635	12	26	(	(	PUNCT
aiua-13635	12	27	54	54	NUM
aiua-13635	12	28	%	%	NOUN
aiua-13635	12	29	of	of	ADP
aiua-13635	12	30	cases	case	NOUN
aiua-13635	12	31	)	)	PUNCT
aiua-13635	12	32	(	(	PUNCT
aiua-13635	12	33	16,17	16,17	NUM
aiua-13635	12	34	)	)	PUNCT
aiua-13635	12	35	and/or	and/or	CCONJ
aiua-13635	12	36	metastatic	metastatic	ADJ
aiua-13635	12	37	pca	pca	NOUN
aiua-13635	12	38	(	(	PUNCT
aiua-13635	12	39	46	46	NUM
aiua-13635	12	40	%	%	NOUN
aiua-13635	12	41	of	of	ADP
aiua-13635	12	42	cases	case	NOUN
aiua-13635	12	43	)	)	PUNCT
aiua-13635	12	44	at	at	ADP
aiua-13635	12	45	initial	initial	ADJ
aiua-13635	12	46	diagnosis	diagnosis	NOUN
aiua-13635	12	47	(	(	PUNCT
aiua-13635	12	48	18	18	NUM
aiua-13635	12	49	)	)	PUNCT
aiua-13635	12	50	,	,	PUNCT
aiua-13635	12	51	hormone	hormone	NOUN
aiua-13635	12	52	-	-	PUNCT
aiua-13635	12	53	sensitive	sensitive	ADJ
aiua-13635	12	54	introduction	introduction	NOUN
aiua-13635	12	55	:	:	PUNCT
aiua-13635	12	56	to	to	PART
aiua-13635	12	57	evaluate	evaluate	VERB
aiua-13635	12	58	brca1	brca1	PROPN
aiua-13635	12	59	-	-	SYM
aiua-13635	12	60	2	2	NUM
aiua-13635	12	61	(	(	PUNCT
aiua-13635	12	62	breast	breast	NOUN
aiua-13635	12	63	cancer	cancer	NOUN
aiua-13635	12	64	)	)	PUNCT
aiua-13635	12	65	detection	detection	NOUN
aiua-13635	12	66	in	in	ADP
aiua-13635	12	67	men	man	NOUN
aiua-13635	12	68	with	with	ADP
aiua-13635	12	69	high	high	ADJ
aiua-13635	12	70	risk	risk	NOUN
aiua-13635	12	71	pca	pca	NOUN
aiua-13635	12	72	,	,	PUNCT
aiua-13635	12	73	including	include	VERB
aiua-13635	12	74	the	the	DET
aiua-13635	12	75	oncological	oncological	ADJ
aiua-13635	12	76	consequences	consequence	NOUN
aiua-13635	12	77	for	for	ADP
aiua-13635	12	78	the	the	DET
aiua-13635	12	79	patient	patient	NOUN
aiua-13635	12	80	and	and	CCONJ
aiua-13635	12	81	family	family	NOUN
aiua-13635	12	82	members	member	NOUN
aiua-13635	12	83	.	.	PUNCT
aiua-13635	13	1	materials	material	NOUN
aiua-13635	13	2	and	and	CCONJ
aiua-13635	13	3	methods	method	NOUN
aiua-13635	13	4	:	:	PUNCT
aiua-13635	13	5	from	from	ADP
aiua-13635	13	6	january	january	PROPN
aiua-13635	13	7	2023	2023	NUM
aiua-13635	13	8	to	to	ADP
aiua-13635	13	9	december	december	PROPN
aiua-13635	13	10	2024	2024	NUM
aiua-13635	13	11	,	,	PUNCT
aiua-13635	13	12	52	52	NUM
aiua-13635	13	13	men	man	NOUN
aiua-13635	13	14	(	(	PUNCT
aiua-13635	13	15	median	median	ADJ
aiua-13635	13	16	age	age	NOUN
aiua-13635	13	17	73	73	NUM
aiua-13635	13	18	years	year	NOUN
aiua-13635	13	19	;)	;)	PUNCT
aiua-13635	13	20	with	with	ADP
aiua-13635	13	21	confirmed	confirm	VERB
aiua-13635	13	22	pca	pca	NOUN
aiua-13635	13	23	diagnosis	diagnosis	NOUN
aiua-13635	13	24	underwent	underwent	NOUN
aiua-13635	13	25	somatic	somatic	ADJ
aiua-13635	13	26	and	and	CCONJ
aiua-13635	13	27	germline	germline	PROPN
aiua-13635	13	28	brca1	brca1	PROPN
aiua-13635	13	29	and	and	CCONJ
aiua-13635	13	30	brca2	brca2	PROPN
aiua-13635	13	31	assessment	assessment	NOUN
aiua-13635	13	32	;	;	PUNCT
aiua-13635	13	33	11/52	11/52	NUM
aiua-13635	13	34	(	(	PUNCT
aiua-13635	13	35	21	21	NUM
aiua-13635	13	36	%	%	NOUN
aiua-13635	13	37	)	)	PUNCT
aiua-13635	14	1	patients	patient	NOUN
aiua-13635	14	2	documented	document	VERB
aiua-13635	14	3	a	a	DET
aiua-13635	14	4	family	family	NOUN
aiua-13635	14	5	history	history	NOUN
aiua-13635	14	6	of	of	ADP
aiua-13635	14	7	cancer	cancer	NOUN
aiua-13635	14	8	.	.	PUNCT
aiua-13635	15	1	patients	patient	NOUN
aiua-13635	15	2	were	be	AUX
aiua-13635	15	3	at	at	ADP
aiua-13635	15	4	different	different	ADJ
aiua-13635	15	5	clinical	clinical	ADJ
aiua-13635	15	6	stages	stage	NOUN
aiua-13635	15	7	:	:	PUNCT
aiua-13635	15	8	high	high	ADJ
aiua-13635	15	9	-	-	PUNCT
aiua-13635	15	10	grade	grade	NOUN
aiua-13635	15	11	(	(	PUNCT
aiua-13635	15	12	71	71	NUM
aiua-13635	15	13	%	%	NOUN
aiua-13635	15	14	had	have	VERB
aiua-13635	15	15	a	a	DET
aiua-13635	15	16	gleason	gleason	PROPN
aiua-13635	15	17	score	score	NOUN
aiua-13635	15	18	≥	≥	PROPN
aiua-13635	15	19	8)	8)	NUM
aiua-13635	15	20	,	,	PUNCT
aiua-13635	15	21	locally	locally	ADV
aiua-13635	15	22	advanced	advanced	ADJ
aiua-13635	15	23	(	(	PUNCT
aiua-13635	15	24	54	54	NUM
aiua-13635	15	25	%	%	NOUN
aiua-13635	15	26	of	of	ADP
aiua-13635	15	27	cases	case	NOUN
aiua-13635	15	28	)	)	PUNCT
aiua-13635	15	29	and/or	and/or	CCONJ
aiua-13635	15	30	metastatic	metastatic	ADJ
aiua-13635	15	31	pca	pca	NOUN
aiua-13635	15	32	(	(	PUNCT
aiua-13635	15	33	46	46	NUM
aiua-13635	15	34	%	%	NOUN
aiua-13635	15	35	of	of	ADP
aiua-13635	15	36	cases	case	NOUN
aiua-13635	15	37	)	)	PUNCT
aiua-13635	15	38	at	at	ADP
aiua-13635	15	39	initial	initial	ADJ
aiua-13635	15	40	diagnosis	diagnosis	NOUN
aiua-13635	15	41	,	,	PUNCT
aiua-13635	15	42	hormone	hormone	NOUN
aiua-13635	15	43	-	-	PUNCT
aiua-13635	15	44	sensitive	sensitive	ADJ
aiua-13635	15	45	and/or	and/or	CCONJ
aiua-13635	15	46	castration	castration	NOUN
aiua-13635	15	47	-	-	PUNCT
aiua-13635	15	48	resistant	resistant	ADJ
aiua-13635	15	49	pca	pca	NOUN
aiua-13635	15	50	(	(	PUNCT
aiua-13635	15	51	38.2	38.2	NUM
aiua-13635	15	52	%	%	NOUN
aiua-13635	15	53	of	of	ADP
aiua-13635	15	54	cases	case	NOUN
aiua-13635	15	55	)	)	PUNCT
aiua-13635	15	56	at	at	ADP
aiua-13635	15	57	clinical	clinical	ADJ
aiua-13635	15	58	progression	progression	NOUN
aiua-13635	15	59	.	.	PUNCT
aiua-13635	16	1	formalin	formalin	NOUN
aiua-13635	16	2	-	-	PUNCT
aiua-13635	16	3	fixed	fix	VERB
aiua-13635	16	4	paraffin	paraffin	NOUN
aiua-13635	16	5	-	-	PUNCT
aiua-13635	16	6	embedded	embed	VERB
aiua-13635	16	7	(	(	PUNCT
aiua-13635	16	8	ffpe	ffpe	NOUN
aiua-13635	16	9	)	)	PUNCT
aiua-13635	16	10	tissues	tissue	NOUN
aiua-13635	16	11	and	and	CCONJ
aiua-13635	17	1	next	next	ADJ
aiua-13635	17	2	generation	generation	NOUN
aiua-13635	17	3	sequencing	sequence	VERB
aiua-13635	17	4	(	(	PUNCT
aiua-13635	17	5	ngs	ng	NOUN
aiua-13635	17	6	)	)	PUNCT
aiua-13635	17	7	analyses	analysis	NOUN
aiua-13635	17	8	of	of	ADP
aiua-13635	17	9	brca	brca	PROPN
aiua-13635	17	10	genes	gene	NOUN
aiua-13635	17	11	were	be	AUX
aiua-13635	17	12	evaluated	evaluate	VERB
aiua-13635	17	13	on	on	ADP
aiua-13635	17	14	52	52	NUM
aiua-13635	17	15	samples	sample	NOUN
aiua-13635	17	16	(	(	PUNCT
aiua-13635	17	17	prostate	prostate	NOUN
aiua-13635	17	18	biopsies	biopsy	NOUN
aiua-13635	17	19	or	or	CCONJ
aiua-13635	17	20	definitive	definitive	ADJ
aiua-13635	17	21	samples	sample	NOUN
aiua-13635	17	22	)	)	PUNCT
aiua-13635	17	23	collected	collect	VERB
aiua-13635	17	24	at	at	ADP
aiua-13635	17	25	gravina	gravina	ADJ
aiua-13635	17	26	hospital	hospital	NOUN
aiua-13635	17	27	(	(	PUNCT
aiua-13635	17	28	caltagirone	caltagirone	PROPN
aiua-13635	17	29	,	,	PUNCT
aiua-13635	17	30	italy	italy	PROPN
aiua-13635	17	31	)	)	PUNCT
aiua-13635	17	32	from	from	ADP
aiua-13635	17	33	different	different	ADJ
aiua-13635	17	34	sicilian	sicilian	ADJ
aiua-13635	17	35	pathology	pathology	NOUN
aiua-13635	17	36	departments	department	NOUN
aiua-13635	17	37	.	.	PUNCT
aiua-13635	18	1	the	the	DET
aiua-13635	18	2	therapeutic	therapeutic	ADJ
aiua-13635	18	3	and	and	CCONJ
aiua-13635	18	4	clinical	clinical	ADJ
aiua-13635	18	5	impact	impact	NOUN
aiua-13635	18	6	of	of	ADP
aiua-13635	18	7	genetic	genetic	ADJ
aiua-13635	18	8	testing	testing	NOUN
aiua-13635	18	9	for	for	ADP
aiua-13635	18	10	brca	brca	PROPN
aiua-13635	18	11	somatic	somatic	ADJ
aiua-13635	18	12	and	and	CCONJ
aiua-13635	18	13	germline	germline	NOUN
aiua-13635	18	14	mutations	mutation	NOUN
aiua-13635	18	15	were	be	AUX
aiua-13635	18	16	evaluated	evaluate	VERB
aiua-13635	18	17	for	for	ADP
aiua-13635	18	18	patients	patient	NOUN
aiua-13635	18	19	and	and	CCONJ
aiua-13635	18	20	their	their	PRON
aiua-13635	18	21	families	family	NOUN
aiua-13635	18	22	.	.	PUNCT
aiua-13635	19	1	results	result	NOUN
aiua-13635	19	2	:	:	PUNCT
aiua-13635	19	3	all	all	DET
aiua-13635	19	4	ffpe	ffpe	ADJ
aiua-13635	19	5	cases	case	NOUN
aiua-13635	19	6	were	be	AUX
aiua-13635	19	7	successfully	successfully	ADV
aiua-13635	19	8	genotyped	genotype	VERB
aiua-13635	19	9	,	,	PUNCT
aiua-13635	19	10	with	with	ADP
aiua-13635	19	11	a	a	DET
aiua-13635	19	12	good	good	ADJ
aiua-13635	19	13	library	library	NOUN
aiua-13635	19	14	and	and	CCONJ
aiua-13635	19	15	sequencing	sequence	VERB
aiua-13635	19	16	cq	cq	NOUN
aiua-13635	19	17	metrics	metric	NOUN
aiua-13635	19	18	for	for	ADP
aiua-13635	19	19	all	all	DET
aiua-13635	19	20	genes	gene	NOUN
aiua-13635	19	21	of	of	ADP
aiua-13635	19	22	interest	interest	NOUN
aiua-13635	19	23	;	;	PUNCT
aiua-13635	19	24	10/52	10/52	NUM
aiua-13635	19	25	(	(	PUNCT
aiua-13635	19	26	19.2	19.2	NUM
aiua-13635	19	27	%	%	NOUN
aiua-13635	19	28	)	)	PUNCT
aiua-13635	19	29	patients	patient	NOUN
aiua-13635	19	30	had	have	VERB
aiua-13635	19	31	somatic	somatic	ADJ
aiua-13635	19	32	or	or	CCONJ
aiua-13635	19	33	germline	germline	NOUN
aiua-13635	19	34	brca	brca	PROPN
aiua-13635	19	35	mutations	mutation	NOUN
aiua-13635	19	36	,	,	PUNCT
aiua-13635	19	37	specifically	specifically	ADV
aiua-13635	19	38	,	,	PUNCT
aiua-13635	19	39	3/52	3/52	NUM
aiua-13635	19	40	(	(	PUNCT
aiua-13635	19	41	5.7	5.7	NUM
aiua-13635	19	42	%	%	NOUN
aiua-13635	19	43	)	)	PUNCT
aiua-13635	19	44	had	have	VERB
aiua-13635	19	45	somatic	somatic	ADJ
aiua-13635	19	46	and	and	CCONJ
aiua-13635	20	1	7/52	7/52	NUM
aiua-13635	20	2	(	(	PUNCT
aiua-13635	20	3	13.5	13.5	NUM
aiua-13635	20	4	%	%	NOUN
aiua-13635	20	5	)	)	PUNCT
aiua-13635	20	6	had	have	VERB
aiua-13635	20	7	germline	germline	NOUN
aiua-13635	20	8	mutations	mutation	NOUN
aiua-13635	20	9	.	.	PUNCT
aiua-13635	21	1	in	in	ADP
aiua-13635	21	2	the	the	DET
aiua-13635	21	3	seven	seven	NUM
aiua-13635	21	4	cases	case	NOUN
aiua-13635	21	5	with	with	ADP
aiua-13635	21	6	germline	germline	NOUN
aiua-13635	21	7	variants	variant	NOUN
aiua-13635	21	8	,	,	PUNCT
aiua-13635	21	9	4/7	4/7	NUM
aiua-13635	21	10	(	(	PUNCT
aiua-13635	21	11	57	57	NUM
aiua-13635	21	12	%	%	NOUN
aiua-13635	21	13	)	)	PUNCT
aiua-13635	21	14	had	have	VERB
aiua-13635	21	15	a	a	DET
aiua-13635	21	16	family	family	NOUN
aiua-13635	21	17	history	history	NOUN
aiua-13635	21	18	of	of	ADP
aiua-13635	21	19	pca	pca	PROPN
aiua-13635	21	20	or	or	CCONJ
aiua-13635	21	21	other	other	ADJ
aiua-13635	21	22	diseases	disease	NOUN
aiua-13635	21	23	,	,	PUNCT
aiua-13635	21	24	while	while	SCONJ
aiua-13635	21	25	the	the	DET
aiua-13635	21	26	remaining	remain	VERB
aiua-13635	21	27	3/7	3/7	NUM
aiua-13635	21	28	(	(	PUNCT
aiua-13635	21	29	43	43	NUM
aiua-13635	21	30	%	%	NOUN
aiua-13635	21	31	)	)	PUNCT
aiua-13635	21	32	patients	patient	NOUN
aiua-13635	21	33	had	have	VERB
aiua-13635	21	34	no	no	DET
aiua-13635	21	35	hereditary	hereditary	ADJ
aiua-13635	21	36	predisposition	predisposition	NOUN
aiua-13635	21	37	.	.	PUNCT
aiua-13635	22	1	all	all	PRON
aiua-13635	22	2	identified	identify	VERB
aiua-13635	22	3	genetic	genetic	ADJ
aiua-13635	22	4	variants	variant	NOUN
aiua-13635	22	5	were	be	AUX
aiua-13635	22	6	related	relate	VERB
aiua-13635	22	7	to	to	ADP
aiua-13635	22	8	the	the	DET
aiua-13635	22	9	brca2	brca2	NOUN
aiua-13635	22	10	gene	gene	NOUN
aiua-13635	22	11	;	;	PUNCT
aiua-13635	22	12	after	after	ADP
aiua-13635	22	13	genetic	genetic	ADJ
aiua-13635	22	14	screening	screening	NOUN
aiua-13635	22	15	of	of	ADP
aiua-13635	22	16	the	the	DET
aiua-13635	22	17	corresponding	corresponding	ADJ
aiua-13635	22	18	relatives	relative	NOUN
aiua-13635	22	19	,	,	PUNCT
aiua-13635	22	20	various	various	ADJ
aiua-13635	22	21	members	member	NOUN
aiua-13635	22	22	of	of	ADP
aiua-13635	22	23	the	the	DET
aiua-13635	22	24	analysed	analyse	VERB
aiua-13635	22	25	families	family	NOUN
aiua-13635	22	26	carried	carry	VERB
aiua-13635	22	27	the	the	DET
aiua-13635	22	28	mutation	mutation	NOUN
aiua-13635	22	29	identified	identify	VERB
aiua-13635	22	30	in	in	ADP
aiua-13635	22	31	the	the	DET
aiua-13635	22	32	proband	proband	NOUN
aiua-13635	22	33	,	,	PUNCT
aiua-13635	22	34	so	so	SCONJ
aiua-13635	22	35	that	that	SCONJ
aiua-13635	22	36	cancer	cancer	NOUN
aiua-13635	22	37	prevention	prevention	NOUN
aiua-13635	22	38	and/or	and/or	CCONJ
aiua-13635	22	39	active	active	ADJ
aiua-13635	22	40	surveillance	surveillance	NOUN
aiua-13635	22	41	was	be	AUX
aiua-13635	22	42	possible	possible	ADJ
aiua-13635	22	43	.	.	PUNCT
aiua-13635	23	1	conclusions	conclusion	NOUN
aiua-13635	23	2	:	:	PUNCT
aiua-13635	23	3	ngs	ng	VERB
aiua-13635	23	4	analysis	analysis	NOUN
aiua-13635	23	5	for	for	ADP
aiua-13635	23	6	brca	brca	PROPN
aiua-13635	23	7	genetic	genetic	ADJ
aiua-13635	23	8	testing	testing	NOUN
aiua-13635	23	9	using	use	VERB
aiua-13635	23	10	ffpe	ffpe	ADJ
aiua-13635	23	11	tissue	tissue	NOUN
aiua-13635	23	12	in	in	ADP
aiua-13635	23	13	the	the	DET
aiua-13635	23	14	clinical	clinical	ADJ
aiua-13635	23	15	setting	setting	NOUN
aiua-13635	23	16	of	of	ADP
aiua-13635	23	17	patients	patient	NOUN
aiua-13635	23	18	with	with	ADP
aiua-13635	23	19	high	high	ADJ
aiua-13635	23	20	-	-	PUNCT
aiua-13635	23	21	grade	grade	NOUN
aiua-13635	23	22	and/or	and/or	CCONJ
aiua-13635	23	23	metastatic	metastatic	ADJ
aiua-13635	23	24	pca	pca	NOUN
aiua-13635	23	25	appears	appear	VERB
aiua-13635	23	26	to	to	PART
aiua-13635	23	27	be	be	AUX
aiua-13635	23	28	a	a	DET
aiua-13635	23	29	valuable	valuable	ADJ
aiua-13635	23	30	tool	tool	NOUN
aiua-13635	23	31	,	,	PUNCT
aiua-13635	23	32	not	not	PART
aiua-13635	23	33	only	only	ADV
aiua-13635	23	34	for	for	ADP
aiua-13635	23	35	therapeutic	therapeutic	ADJ
aiua-13635	23	36	purposes	purpose	NOUN
aiua-13635	23	37	,	,	PUNCT
aiua-13635	23	38	but	but	CCONJ
aiua-13635	23	39	also	also	ADV
aiua-13635	23	40	to	to	PART
aiua-13635	23	41	identify	identify	VERB
aiua-13635	23	42	families	family	NOUN
aiua-13635	23	43	with	with	ADP
aiua-13635	23	44	genetic	genetic	ADJ
aiua-13635	23	45	predisposition	predisposition	NOUN
aiua-13635	23	46	who	who	PRON
aiua-13635	23	47	may	may	AUX
aiua-13635	23	48	be	be	AUX
aiua-13635	23	49	underdiagnosed	underdiagnose	VERB
aiua-13635	23	50	according	accord	VERB
aiua-13635	23	51	to	to	ADP
aiua-13635	23	52	canonical	canonical	ADJ
aiua-13635	23	53	criteria	criterion	NOUN
aiua-13635	23	54	.	.	PUNCT
aiua-13635	24	1	key	key	ADJ
aiua-13635	24	2	words	word	NOUN
aiua-13635	24	3	:	:	PUNCT
aiua-13635	24	4	prostate	prostate	NOUN
aiua-13635	24	5	cancer	cancer	NOUN
aiua-13635	24	6	;	;	PUNCT
aiua-13635	24	7	brca	brca	PROPN
aiua-13635	24	8	and	and	CCONJ
aiua-13635	24	9	high	high	ADJ
aiua-13635	24	10	grade	grade	NOUN
aiua-13635	24	11	pca	pca	PROPN
aiua-13635	24	12	;	;	PUNCT
aiua-13635	24	13	brca	brca	PROPN
aiua-13635	24	14	mutations	mutation	NOUN
aiua-13635	24	15	and	and	CCONJ
aiua-13635	24	16	pca	pca	NOUN
aiua-13635	24	17	:	:	PUNCT
aiua-13635	24	18	somatic	somatic	ADJ
aiua-13635	24	19	and	and	CCONJ
aiua-13635	24	20	germline	germline	PROPN
aiua-13635	24	21	brca	brca	PROPN
aiua-13635	24	22	.	.	PROPN
aiua-13635	24	23	submitted	submit	VERB
aiua-13635	24	24	15	15	NUM
aiua-13635	24	25	january	january	NOUN
aiua-13635	24	26	2025	2025	NUM
aiua-13635	24	27	;	;	PUNCT
aiua-13635	24	28	accepted	accept	VERB
aiua-13635	24	29	21	21	NUM
aiua-13635	24	30	january	january	PROPN
aiua-13635	24	31	2025	2025	NUM
aiua-13635	24	32	brca	brca	PROPN
aiua-13635	24	33	mutations	mutation	NOUN
aiua-13635	24	34	and	and	CCONJ
aiua-13635	24	35	prostate	prostate	NOUN
aiua-13635	24	36	cancer	cancer	NOUN
aiua-13635	24	37	:	:	PUNCT
aiua-13635	24	38	should	should	AUX
aiua-13635	24	39	urologist	urologist	NOUN
aiua-13635	24	40	improve	improve	VERB
aiua-13635	24	41	daily	daily	ADJ
aiua-13635	24	42	clinical	clinical	ADJ
aiua-13635	24	43	practice	practice	NOUN
aiua-13635	24	44	?	?	PUNCT
aiua-13635	25	1	simona	simona	PROPN
aiua-13635	25	2	vatrano	vatrano	PROPN
aiua-13635	25	3	1	1	NUM
aiua-13635	25	4	,	,	PUNCT
aiua-13635	25	5	pietro	pietro	NOUN
aiua-13635	25	6	pepe	pepe	PROPN
aiua-13635	25	7	2	2	NUM
aiua-13635	25	8	,	,	PUNCT
aiua-13635	25	9	ludovica	ludovica	PROPN
aiua-13635	25	10	pepe	pepe	PROPN
aiua-13635	25	11	2	2	NUM
aiua-13635	25	12	,	,	PUNCT
aiua-13635	25	13	nuccia	nuccia	NOUN
aiua-13635	25	14	vella	vella	NOUN
aiua-13635	25	15	3	3	NUM
aiua-13635	25	16	,	,	PUNCT
aiua-13635	25	17	cristina	cristina	PROPN
aiua-13635	25	18	alario	alario	PROPN
aiua-13635	25	19	1	1	NUM
aiua-13635	25	20	,	,	PUNCT
aiua-13635	25	21	alessia	alessia	PROPN
aiua-13635	25	22	chiarandà	chiarandà	VERB
aiua-13635	25	23	1	1	NUM
aiua-13635	25	24	,	,	PUNCT
aiua-13635	25	25	chiara	chiara	X
aiua-13635	25	26	taranto	taranto	PROPN
aiua-13635	25	27	1	1	NUM
aiua-13635	25	28	,	,	PUNCT
aiua-13635	25	29	renato	renato	PROPN
aiua-13635	25	30	scillieri	scillieri	PROPN
aiua-13635	25	31	4	4	NUM
aiua-13635	25	32	,	,	PUNCT
aiua-13635	25	33	cristina	cristina	PROPN
aiua-13635	25	34	mauceri	mauceri	PROPN
aiua-13635	25	35	4	4	NUM
aiua-13635	25	36	,	,	PUNCT
aiua-13635	25	37	filippo	filippo	X
aiua-13635	25	38	fraggetta	fraggetta	VERB
aiua-13635	25	39	1	1	NUM
aiua-13635	25	40	1	1	NUM
aiua-13635	25	41	pathology	pathology	NOUN
aiua-13635	25	42	unit	unit	NOUN
aiua-13635	25	43	-	-	PUNCT
aiua-13635	25	44	gravina	gravina	NOUN
aiua-13635	25	45	hospital	hospital	NOUN
aiua-13635	25	46	,	,	PUNCT
aiua-13635	25	47	caltagirone	caltagirone	PROPN
aiua-13635	25	48	,	,	PUNCT
aiua-13635	25	49	italy	italy	PROPN
aiua-13635	25	50	;	;	PUNCT
aiua-13635	25	51	2	2	NUM
aiua-13635	25	52	urology	urology	NOUN
aiua-13635	25	53	unit	unit	NOUN
aiua-13635	25	54	-	-	PUNCT
aiua-13635	25	55	cannizzaro	cannizzaro	NOUN
aiua-13635	25	56	hospital	hospital	NOUN
aiua-13635	25	57	,	,	PUNCT
aiua-13635	25	58	catania	catania	PROPN
aiua-13635	25	59	,	,	PUNCT
aiua-13635	25	60	italy	italy	PROPN
aiua-13635	25	61	;	;	PUNCT
aiua-13635	25	62	3	3	NUM
aiua-13635	25	63	genetic	genetic	ADJ
aiua-13635	25	64	unit	unit	NOUN
aiua-13635	25	65	-	-	PUNCT
aiua-13635	25	66	vittorio	vittorio	PROPN
aiua-13635	25	67	emanuele	emanuele	PROPN
aiua-13635	25	68	hospital	hospital	PROPN
aiua-13635	25	69	,	,	PUNCT
aiua-13635	25	70	gela	gela	PROPN
aiua-13635	25	71	,	,	PUNCT
aiua-13635	25	72	italy	italy	PROPN
aiua-13635	25	73	;	;	PUNCT
aiua-13635	25	74	4	4	NUM
aiua-13635	25	75	oncologic	oncologic	NOUN
aiua-13635	25	76	screening	screen	VERB
aiua-13635	25	77	unit	unit	NOUN
aiua-13635	25	78	-	-	PUNCT
aiua-13635	25	79	catania	catania	PROPN
aiua-13635	25	80	,	,	PUNCT
aiua-13635	25	81	italy	italy	PROPN
aiua-13635	25	82	.	.	PUNCT
aiua-13635	26	1	doi	doi	PROPN
aiua-13635	26	2	:	:	PUNCT
aiua-13635	26	3	10.4081	10.4081	NUM
aiua-13635	26	4	/	/	SYM
aiua-13635	26	5	aiua.2025.13635	aiua.2025.13635	ADP
aiua-13635	26	6	summary	summary	NOUN
aiua-13635	26	7	archivio	archivio	NOUN
aiua-13635	26	8	italiano	italiano	X
aiua-13635	26	9	di	di	X
aiua-13635	26	10	urologia	urologia	PROPN
aiua-13635	26	11	e	e	PROPN
aiua-13635	26	12	andrologia	andrologia	NOUN
aiua-13635	26	13	2025	2025	NUM
aiua-13635	26	14	;	;	PUNCT
aiua-13635	26	15	97(2):13635	97(2):13635	PROPN
aiua-13635	26	16	s.	s.	PROPN
aiua-13635	26	17	vatrano	vatrano	PROPN
aiua-13635	26	18	,	,	PUNCT
aiua-13635	26	19	p.	p.	PROPN
aiua-13635	26	20	pepe	pepe	PROPN
aiua-13635	26	21	,	,	PUNCT
aiua-13635	26	22	l.	l.	PROPN
aiua-13635	26	23	pepe	pepe	PROPN
aiua-13635	26	24	,	,	PUNCT
aiua-13635	26	25	et	et	PROPN
aiua-13635	26	26	al	al	PROPN
aiua-13635	26	27	.	.	PROPN
aiua-13635	26	28	2	2	NUM
aiua-13635	26	29	and/or	and/or	CCONJ
aiua-13635	26	30	castration	castration	NOUN
aiua-13635	26	31	-	-	PUNCT
aiua-13635	26	32	resistant	resistant	ADJ
aiua-13635	26	33	pca	pca	NOUN
aiua-13635	26	34	(	(	PUNCT
aiua-13635	26	35	38.2	38.2	NUM
aiua-13635	26	36	%	%	NOUN
aiua-13635	26	37	of	of	ADP
aiua-13635	26	38	cases	case	NOUN
aiua-13635	26	39	)	)	PUNCT
aiua-13635	26	40	at	at	ADP
aiua-13635	26	41	clinical	clinical	ADJ
aiua-13635	26	42	progression	progression	NOUN
aiua-13635	26	43	(	(	PUNCT
aiua-13635	26	44	19	19	NUM
aiua-13635	26	45	-	-	SYM
aiua-13635	26	46	21	21	NUM
aiua-13635	26	47	)	)	PUNCT
aiua-13635	26	48	.	.	PUNCT
aiua-13635	27	1	after	after	SCONJ
aiua-13635	27	2	institutional	institutional	ADJ
aiua-13635	27	3	review	review	NOUN
aiua-13635	27	4	board	board	PROPN
aiua-13635	27	5	and	and	CCONJ
aiua-13635	27	6	ethical	ethical	ADJ
aiua-13635	27	7	committee	committee	NOUN
aiua-13635	27	8	approval	approval	NOUN
aiua-13635	27	9	were	be	AUX
aiua-13635	27	10	granted	grant	VERB
aiua-13635	27	11	,	,	PUNCT
aiua-13635	27	12	the	the	DET
aiua-13635	27	13	informed	informed	ADJ
aiua-13635	27	14	consent	consent	NOUN
aiua-13635	27	15	was	be	AUX
aiua-13635	27	16	obtained	obtain	VERB
aiua-13635	27	17	from	from	ADP
aiua-13635	27	18	all	all	DET
aiua-13635	27	19	individual	individual	ADJ
aiua-13635	27	20	participants	participant	NOUN
aiua-13635	27	21	included	include	VERB
aiua-13635	27	22	in	in	ADP
aiua-13635	27	23	the	the	DET
aiua-13635	27	24	study	study	NOUN
aiua-13635	27	25	.	.	PUNCT
aiua-13635	28	1	all	all	DET
aiua-13635	28	2	clinical	clinical	ADJ
aiua-13635	28	3	parameters	parameter	NOUN
aiua-13635	28	4	of	of	ADP
aiua-13635	28	5	the	the	DET
aiua-13635	28	6	patients	patient	NOUN
aiua-13635	28	7	are	be	AUX
aiua-13635	28	8	listed	list	VERB
aiua-13635	28	9	in	in	ADP
aiua-13635	28	10	table	table	NOUN
aiua-13635	28	11	1	1	NUM
aiua-13635	28	12	.	.	PUNCT
aiua-13635	28	13	formalin	formalin	NOUN
aiua-13635	28	14	-	-	PUNCT
aiua-13635	28	15	fixed	fix	VERB
aiua-13635	28	16	paraffinembedded	paraffinembedde	VERB
aiua-13635	28	17	(	(	PUNCT
aiua-13635	28	18	ffpe	ffpe	NOUN
aiua-13635	28	19	)	)	PUNCT
aiua-13635	28	20	tissues	tissue	NOUN
aiua-13635	28	21	and	and	CCONJ
aiua-13635	28	22	next	next	ADJ
aiua-13635	28	23	generation	generation	NOUN
aiua-13635	28	24	sequencing	sequence	VERB
aiua-13635	28	25	(	(	PUNCT
aiua-13635	28	26	ngs	ng	NOUN
aiua-13635	28	27	)	)	PUNCT
aiua-13635	28	28	analyses	analysis	NOUN
aiua-13635	28	29	of	of	ADP
aiua-13635	28	30	brca	brca	PROPN
aiua-13635	28	31	genes	gene	NOUN
aiua-13635	28	32	were	be	AUX
aiua-13635	28	33	evaluated	evaluate	VERB
aiua-13635	28	34	(	(	PUNCT
aiua-13635	28	35	22	22	NUM
aiua-13635	28	36	-	-	SYM
aiua-13635	28	37	24	24	NUM
aiua-13635	28	38	)	)	PUNCT
aiua-13635	28	39	on	on	ADP
aiua-13635	28	40	52	52	NUM
aiua-13635	28	41	samples	sample	NOUN
aiua-13635	28	42	(	(	PUNCT
aiua-13635	28	43	prostate	prostate	NOUN
aiua-13635	28	44	biopsies	biopsy	NOUN
aiua-13635	28	45	or	or	CCONJ
aiua-13635	28	46	definitive	definitive	ADJ
aiua-13635	28	47	samples	sample	NOUN
aiua-13635	28	48	)	)	PUNCT
aiua-13635	28	49	collected	collect	VERB
aiua-13635	28	50	at	at	ADP
aiua-13635	28	51	gravina	gravina	ADJ
aiua-13635	28	52	hospital	hospital	NOUN
aiua-13635	28	53	of	of	ADP
aiua-13635	28	54	caltagirone	caltagirone	NOUN
aiua-13635	28	55	(	(	PUNCT
aiua-13635	28	56	referral	referral	ADJ
aiua-13635	28	57	center	center	NOUN
aiua-13635	28	58	for	for	ADP
aiua-13635	28	59	genetic	genetic	ADJ
aiua-13635	28	60	analysis	analysis	NOUN
aiua-13635	28	61	)	)	PUNCT
aiua-13635	28	62	from	from	ADP
aiua-13635	28	63	different	different	ADJ
aiua-13635	28	64	sicilian	sicilian	ADJ
aiua-13635	28	65	pathology	pathology	NOUN
aiua-13635	28	66	departments	department	NOUN
aiua-13635	28	67	(	(	PUNCT
aiua-13635	28	68	25	25	NUM
aiua-13635	28	69	,	,	PUNCT
aiua-13635	28	70	26	26	NUM
aiua-13635	28	71	)	)	PUNCT
aiua-13635	28	72	.	.	PUNCT
aiua-13635	29	1	in	in	ADP
aiua-13635	29	2	addition	addition	NOUN
aiua-13635	29	3	,	,	PUNCT
aiua-13635	29	4	the	the	DET
aiua-13635	29	5	therapeutic	therapeutic	ADJ
aiua-13635	29	6	and	and	CCONJ
aiua-13635	29	7	clinical	clinical	ADJ
aiua-13635	29	8	impact	impact	NOUN
aiua-13635	29	9	of	of	ADP
aiua-13635	29	10	genetic	genetic	ADJ
aiua-13635	29	11	testing	testing	NOUN
aiua-13635	29	12	for	for	ADP
aiua-13635	29	13	brca	brca	PROPN
aiua-13635	29	14	somatic	somatic	ADJ
aiua-13635	29	15	and	and	CCONJ
aiua-13635	29	16	germline	germline	NOUN
aiua-13635	29	17	mutations	mutation	NOUN
aiua-13635	29	18	was	be	AUX
aiua-13635	29	19	evaluated	evaluate	VERB
aiua-13635	29	20	for	for	ADP
aiua-13635	29	21	patients	patient	NOUN
aiua-13635	29	22	and	and	CCONJ
aiua-13635	29	23	their	their	PRON
aiua-13635	29	24	families	family	NOUN
aiua-13635	29	25	.	.	PUNCT
aiua-13635	30	1	by	by	ADP
aiua-13635	30	2	aligning	align	VERB
aiua-13635	30	3	all	all	DET
aiua-13635	30	4	sequencing	sequence	VERB
aiua-13635	30	5	results	result	NOUN
aiua-13635	30	6	obtained	obtain	VERB
aiua-13635	30	7	with	with	ADP
aiua-13635	30	8	ngs	ng	NOUN
aiua-13635	30	9	analysis	analysis	NOUN
aiua-13635	30	10	of	of	ADP
aiua-13635	30	11	ffpe	ffpe	ADJ
aiua-13635	30	12	tissue	tissue	NOUN
aiua-13635	30	13	and	and	CCONJ
aiua-13635	30	14	peripheral	peripheral	ADJ
aiua-13635	30	15	blood	blood	NOUN
aiua-13635	30	16	,	,	PUNCT
aiua-13635	30	17	good	good	ADJ
aiua-13635	30	18	coverage	coverage	NOUN
aiua-13635	30	19	and	and	CCONJ
aiua-13635	30	20	uniformity	uniformity	NOUN
aiua-13635	30	21	was	be	AUX
aiua-13635	30	22	achieved	achieve	VERB
aiua-13635	30	23	for	for	ADP
aiua-13635	30	24	all	all	DET
aiua-13635	30	25	samples	sample	NOUN
aiua-13635	30	26	with	with	ADP
aiua-13635	30	27	optimal	optimal	ADJ
aiua-13635	30	28	read	read	NOUN
aiua-13635	30	29	quality	quality	NOUN
aiua-13635	30	30	and	and	CCONJ
aiua-13635	30	31	sequencing	sequence	VERB
aiua-13635	30	32	metrics	metric	NOUN
aiua-13635	30	33	for	for	ADP
aiua-13635	30	34	both	both	DET
aiua-13635	30	35	analyzed	analyze	VERB
aiua-13635	30	36	genes	gene	NOUN
aiua-13635	30	37	.	.	PUNCT
aiua-13635	31	1	results	result	VERB
aiua-13635	31	2	all	all	DET
aiua-13635	31	3	ffpe	ffpe	ADJ
aiua-13635	31	4	cases	case	NOUN
aiua-13635	31	5	were	be	AUX
aiua-13635	31	6	successfully	successfully	ADV
aiua-13635	31	7	genotyped	genotype	VERB
aiua-13635	31	8	,	,	PUNCT
aiua-13635	31	9	with	with	ADP
aiua-13635	31	10	a	a	DET
aiua-13635	31	11	good	good	ADJ
aiua-13635	31	12	library	library	NOUN
aiua-13635	31	13	and	and	CCONJ
aiua-13635	31	14	sequencing	sequence	VERB
aiua-13635	31	15	cq	cq	NOUN
aiua-13635	31	16	metrics	metric	NOUN
aiua-13635	31	17	for	for	ADP
aiua-13635	31	18	all	all	DET
aiua-13635	31	19	genes	gene	NOUN
aiua-13635	31	20	of	of	ADP
aiua-13635	31	21	interest	interest	NOUN
aiua-13635	31	22	.	.	PUNCT
aiua-13635	32	1	a	a	DET
aiua-13635	32	2	good	good	ADJ
aiua-13635	32	3	sequencing	sequence	VERB
aiua-13635	32	4	performance	performance	NOUN
aiua-13635	32	5	was	be	AUX
aiua-13635	32	6	also	also	ADV
aiua-13635	32	7	achieved	achieve	VERB
aiua-13635	32	8	for	for	ADP
aiua-13635	32	9	old	old	ADJ
aiua-13635	32	10	archival	archival	NOUN
aiua-13635	32	11	samples	sample	NOUN
aiua-13635	32	12	(	(	PUNCT
aiua-13635	32	13	i.e.	i.e.	X
aiua-13635	32	14	histological	histological	ADJ
aiua-13635	32	15	samples	sample	NOUN
aiua-13635	32	16	from	from	ADP
aiua-13635	32	17	2009	2009	NUM
aiua-13635	32	18	)	)	PUNCT
aiua-13635	32	19	.	.	PUNCT
aiua-13635	33	1	most	most	ADJ
aiua-13635	33	2	of	of	ADP
aiua-13635	33	3	the	the	DET
aiua-13635	33	4	identified	identify	VERB
aiua-13635	33	5	genetic	genetic	ADJ
aiua-13635	33	6	variants	variant	NOUN
aiua-13635	33	7	had	have	AUX
aiua-13635	33	8	been	be	AUX
aiua-13635	33	9	previously	previously	ADV
aiua-13635	33	10	reported	report	VERB
aiua-13635	33	11	in	in	ADP
aiua-13635	33	12	the	the	DET
aiua-13635	33	13	major	major	ADJ
aiua-13635	33	14	mutation	mutation	NOUN
aiua-13635	33	15	databases	database	NOUN
aiua-13635	33	16	with	with	ADP
aiua-13635	33	17	clinical	clinical	ADJ
aiua-13635	33	18	impact	impact	NOUN
aiua-13635	33	19	,	,	PUNCT
aiua-13635	33	20	being	be	AUX
aiua-13635	33	21	distributed	distribute	VERB
aiua-13635	33	22	among	among	ADP
aiua-13635	33	23	the	the	DET
aiua-13635	33	24	different	different	ADJ
aiua-13635	33	25	genes	gene	NOUN
aiua-13635	33	26	and	and	CCONJ
aiua-13635	33	27	all	all	PRON
aiua-13635	33	28	resulting	result	VERB
aiua-13635	33	29	in	in	ADP
aiua-13635	33	30	a	a	DET
aiua-13635	33	31	truncated	truncated	ADJ
aiua-13635	33	32	non	non	ADJ
aiua-13635	33	33	-	-	ADJ
aiua-13635	33	34	functional	functional	ADJ
aiua-13635	33	35	protein	protein	NOUN
aiua-13635	33	36	.	.	PUNCT
aiua-13635	34	1	10/52	10/52	NUM
aiua-13635	34	2	(	(	PUNCT
aiua-13635	34	3	19.2	19.2	NUM
aiua-13635	34	4	%	%	NOUN
aiua-13635	34	5	)	)	PUNCT
aiua-13635	35	1	patients	patient	NOUN
aiua-13635	35	2	had	have	VERB
aiua-13635	35	3	somatic	somatic	ADJ
aiua-13635	35	4	or	or	CCONJ
aiua-13635	35	5	germline	germline	NOUN
aiua-13635	35	6	brca	brca	PROPN
aiua-13635	35	7	mutations	mutation	NOUN
aiua-13635	35	8	(	(	PUNCT
aiua-13635	35	9	table	table	NOUN
aiua-13635	35	10	2	2	NUM
aiua-13635	35	11	)	)	PUNCT
aiua-13635	35	12	;	;	PUNCT
aiua-13635	35	13	specifically	specifically	ADV
aiua-13635	35	14	,	,	PUNCT
aiua-13635	35	15	3/52	3/52	NUM
aiua-13635	35	16	(	(	PUNCT
aiua-13635	35	17	5.7	5.7	NUM
aiua-13635	35	18	%	%	NOUN
aiua-13635	35	19	)	)	PUNCT
aiua-13635	35	20	had	have	VERB
aiua-13635	35	21	somatic	somatic	ADJ
aiua-13635	35	22	and	and	CCONJ
aiua-13635	35	23	7/52	7/52	NUM
aiua-13635	35	24	(	(	PUNCT
aiua-13635	35	25	13.5	13.5	NUM
aiua-13635	35	26	%	%	NOUN
aiua-13635	35	27	)	)	PUNCT
aiua-13635	35	28	had	have	VERB
aiua-13635	35	29	germline	germline	NOUN
aiua-13635	35	30	mutations	mutation	NOUN
aiua-13635	35	31	.	.	PUNCT
aiua-13635	36	1	in	in	ADP
aiua-13635	36	2	the	the	DET
aiua-13635	36	3	seven	seven	NUM
aiua-13635	36	4	cases	case	NOUN
aiua-13635	36	5	with	with	ADP
aiua-13635	36	6	germline	germline	NOUN
aiua-13635	36	7	variants	variant	NOUN
aiua-13635	36	8	,	,	PUNCT
aiua-13635	36	9	4/7	4/7	NUM
aiua-13635	36	10	(	(	PUNCT
aiua-13635	36	11	57	57	NUM
aiua-13635	36	12	%	%	NOUN
aiua-13635	36	13	)	)	PUNCT
aiua-13635	36	14	had	have	VERB
aiua-13635	36	15	a	a	DET
aiua-13635	36	16	family	family	NOUN
aiua-13635	36	17	history	history	NOUN
aiua-13635	36	18	of	of	ADP
aiua-13635	36	19	pca	pca	PROPN
aiua-13635	36	20	or	or	CCONJ
aiua-13635	36	21	other	other	ADJ
aiua-13635	36	22	diseases	disease	NOUN
aiua-13635	36	23	,	,	PUNCT
aiua-13635	36	24	while	while	SCONJ
aiua-13635	36	25	the	the	DET
aiua-13635	36	26	remaining	remain	VERB
aiua-13635	36	27	3/7	3/7	NUM
aiua-13635	36	28	(	(	PUNCT
aiua-13635	36	29	43	43	NUM
aiua-13635	36	30	%	%	NOUN
aiua-13635	36	31	)	)	PUNCT
aiua-13635	36	32	patients	patient	NOUN
aiua-13635	36	33	had	have	VERB
aiua-13635	36	34	no	no	DET
aiua-13635	36	35	hereditary	hereditary	ADJ
aiua-13635	36	36	predisposition	predisposition	NOUN
aiua-13635	36	37	.	.	PUNCT
aiua-13635	37	1	all	all	PRON
aiua-13635	37	2	identified	identify	VERB
aiua-13635	37	3	genetic	genetic	ADJ
aiua-13635	37	4	variants	variant	NOUN
aiua-13635	37	5	had	have	AUX
aiua-13635	37	6	been	be	AUX
aiua-13635	37	7	previously	previously	ADV
aiua-13635	37	8	described	describe	VERB
aiua-13635	37	9	in	in	ADP
aiua-13635	37	10	the	the	DET
aiua-13635	37	11	major	major	ADJ
aiua-13635	37	12	mutation	mutation	NOUN
aiua-13635	37	13	databases	database	NOUN
aiua-13635	37	14	,	,	PUNCT
aiua-13635	37	15	and	and	CCONJ
aiua-13635	37	16	most	most	ADJ
aiua-13635	37	17	of	of	ADP
aiua-13635	37	18	them	they	PRON
aiua-13635	37	19	were	be	AUX
aiua-13635	37	20	related	relate	VERB
aiua-13635	37	21	to	to	ADP
aiua-13635	37	22	the	the	DET
aiua-13635	37	23	brca2	brca2	NOUN
aiua-13635	37	24	gene	gene	NOUN
aiua-13635	37	25	.	.	PUNCT
aiua-13635	38	1	in	in	ADP
aiua-13635	38	2	detail	detail	NOUN
aiua-13635	38	3	,	,	PUNCT
aiua-13635	38	4	3/10	3/10	NUM
aiua-13635	38	5	(	(	PUNCT
aiua-13635	38	6	30	30	NUM
aiua-13635	38	7	%	%	NOUN
aiua-13635	38	8	)	)	PUNCT
aiua-13635	38	9	patients	patient	NOUN
aiua-13635	38	10	without	without	ADP
aiua-13635	38	11	a	a	DET
aiua-13635	38	12	family	family	NOUN
aiua-13635	38	13	history	history	NOUN
aiua-13635	38	14	of	of	ADP
aiua-13635	38	15	cancer	cancer	NOUN
aiua-13635	38	16	had	have	AUX
aiua-13635	38	17	germline	germline	NOUN
aiua-13635	38	18	mutations	mutation	NOUN
aiua-13635	38	19	in	in	ADP
aiua-13635	38	20	the	the	DET
aiua-13635	38	21	brca	brca	PROPN
aiua-13635	38	22	genes	gene	NOUN
aiua-13635	38	23	that	that	PRON
aiua-13635	38	24	had	have	VERB
aiua-13635	38	25	predictive	predictive	ADJ
aiua-13635	38	26	significance	significance	NOUN
aiua-13635	38	27	but	but	CCONJ
aiua-13635	38	28	also	also	ADV
aiua-13635	38	29	clinical	clinical	ADJ
aiua-13635	38	30	impact	impact	NOUN
aiua-13635	38	31	on	on	ADP
aiua-13635	38	32	their	their	PRON
aiua-13635	38	33	relatives	relative	NOUN
aiua-13635	38	34	.	.	PUNCT
aiua-13635	39	1	after	after	ADP
aiua-13635	39	2	genetic	genetic	ADJ
aiua-13635	39	3	screening	screening	NOUN
aiua-13635	39	4	of	of	ADP
aiua-13635	39	5	the	the	DET
aiua-13635	39	6	corresponding	corresponding	ADJ
aiua-13635	39	7	relatives	relative	NOUN
aiua-13635	39	8	,	,	PUNCT
aiua-13635	39	9	various	various	ADJ
aiua-13635	39	10	members	member	NOUN
aiua-13635	39	11	of	of	ADP
aiua-13635	39	12	the	the	DET
aiua-13635	39	13	analyzed	analyze	VERB
aiua-13635	39	14	families	family	NOUN
aiua-13635	39	15	(	(	PUNCT
aiua-13635	39	16	figure	figure	NOUN
aiua-13635	39	17	1	1	NUM
aiua-13635	39	18	)	)	PUNCT
aiua-13635	39	19	carried	carry	VERB
aiua-13635	39	20	the	the	DET
aiua-13635	39	21	mutation	mutation	NOUN
aiua-13635	39	22	identified	identify	VERB
aiua-13635	39	23	in	in	ADP
aiua-13635	39	24	the	the	DET
aiua-13635	39	25	proband	proband	NOUN
aiua-13635	39	26	,	,	PUNCT
aiua-13635	39	27	so	so	SCONJ
aiua-13635	39	28	that	that	SCONJ
aiua-13635	39	29	cancer	cancer	NOUN
aiua-13635	39	30	prevention	prevention	NOUN
aiua-13635	39	31	and/or	and/or	CCONJ
aiua-13635	39	32	active	active	ADJ
aiua-13635	39	33	surveillance	surveillance	NOUN
aiua-13635	39	34	was	be	AUX
aiua-13635	39	35	possible	possible	ADJ
aiua-13635	39	36	.	.	PUNCT
aiua-13635	40	1	discussion	discussion	NOUN
aiua-13635	40	2	several	several	ADJ
aiua-13635	40	3	sequencing	sequence	VERB
aiua-13635	40	4	studies	study	NOUN
aiua-13635	40	5	have	have	AUX
aiua-13635	40	6	shown	show	VERB
aiua-13635	40	7	that	that	SCONJ
aiua-13635	40	8	approximately	approximately	ADV
aiua-13635	40	9	25	25	NUM
aiua-13635	40	10	%	%	NOUN
aiua-13635	40	11	of	of	ADP
aiua-13635	40	12	metastatic	metastatic	ADJ
aiua-13635	40	13	castration	castration	NOUN
aiua-13635	40	14	-	-	PUNCT
aiua-13635	40	15	resistant	resistant	ADJ
aiua-13635	40	16	pca	pca	NOUN
aiua-13635	40	17	patients	patient	NOUN
aiua-13635	40	18	have	have	VERB
aiua-13635	40	19	genomically	genomically	ADV
aiua-13635	40	20	aberrant	aberrant	ADJ
aiua-13635	40	21	dna	dna	PROPN
aiua-13635	40	22	repair	repair	NOUN
aiua-13635	40	23	pathways	pathway	NOUN
aiua-13635	40	24	,	,	PUNCT
aiua-13635	40	25	with	with	ADP
aiua-13635	40	26	mutations	mutation	NOUN
aiua-13635	40	27	in	in	ADP
aiua-13635	40	28	the	the	DET
aiua-13635	40	29	brca1	brca1	NOUN
aiua-13635	40	30	and	and	CCONJ
aiua-13635	40	31	brca2	brca2	NOUN
aiua-13635	40	32	genes	gene	NOUN
aiua-13635	40	33	,	,	PUNCT
aiua-13635	40	34	which	which	PRON
aiua-13635	40	35	have	have	AUX
aiua-13635	40	36	been	be	AUX
aiua-13635	40	37	of	of	ADP
aiua-13635	40	38	important	important	ADJ
aiua-13635	40	39	clinical	clinical	ADJ
aiua-13635	40	40	and	and	CCONJ
aiua-13635	40	41	therapeutic	therapeutic	ADJ
aiua-13635	40	42	significance	significance	NOUN
aiua-13635	40	43	since	since	SCONJ
aiua-13635	40	44	the	the	DET
aiua-13635	40	45	approval	approval	NOUN
aiua-13635	40	46	of	of	ADP
aiua-13635	40	47	parp	parp	ADJ
aiua-13635	40	48	inhibitors	inhibitor	NOUN
aiua-13635	40	49	in	in	ADP
aiua-13635	40	50	castration	castration	NOUN
aiua-13635	40	51	-	-	PUNCT
aiua-13635	40	52	resistant	resistant	ADJ
aiua-13635	40	53	patients	patient	NOUN
aiua-13635	40	54	(	(	PUNCT
aiua-13635	40	55	1	1	NUM
aiua-13635	40	56	)	)	PUNCT
aiua-13635	40	57	.	.	PUNCT
aiua-13635	41	1	of	of	ADP
aiua-13635	41	2	all	all	DET
aiua-13635	41	3	brca	brca	PROPN
aiua-13635	41	4	-	-	PUNCT
aiua-13635	41	5	mutated	mutate	VERB
aiua-13635	41	6	metastatic	metastatic	ADJ
aiua-13635	41	7	pca	pca	NOUN
aiua-13635	41	8	,	,	PUNCT
aiua-13635	41	9	about	about	ADV
aiua-13635	41	10	half	half	NOUN
aiua-13635	41	11	had	have	VERB
aiua-13635	41	12	somatic	somatic	ADJ
aiua-13635	41	13	mutations	mutation	NOUN
aiua-13635	41	14	and	and	CCONJ
aiua-13635	41	15	the	the	DET
aiua-13635	41	16	others	other	NOUN
aiua-13635	41	17	had	have	VERB
aiua-13635	41	18	germline	germline	NOUN
aiua-13635	41	19	mutations	mutation	NOUN
aiua-13635	41	20	(	(	PUNCT
aiua-13635	41	21	27	27	NUM
aiua-13635	41	22	)	)	PUNCT
aiua-13635	41	23	;	;	PUNCT
aiua-13635	41	24	hommerding	hommerde	VERB
aiua-13635	41	25	et	et	PROPN
aiua-13635	41	26	al	al	PROPN
aiua-13635	41	27	.	.	PUNCT
aiua-13635	42	1	(	(	PUNCT
aiua-13635	42	2	28	28	NUM
aiua-13635	42	3	)	)	PUNCT
aiua-13635	42	4	reported	report	VERB
aiua-13635	42	5	a	a	DET
aiua-13635	42	6	prevalence	prevalence	NOUN
aiua-13635	42	7	of	of	ADP
aiua-13635	42	8	potentially	potentially	ADV
aiua-13635	42	9	targetable	targetable	ADJ
aiua-13635	42	10	genetic	genetic	ADJ
aiua-13635	42	11	mutation	mutation	NOUN
aiua-13635	42	12	table	table	NOUN
aiua-13635	42	13	1	1	NUM
aiua-13635	42	14	.	.	PUNCT
aiua-13635	43	1	clinical	clinical	ADJ
aiua-13635	43	2	findings	finding	NOUN
aiua-13635	43	3	in	in	ADP
aiua-13635	43	4	the	the	DET
aiua-13635	43	5	52	52	NUM
aiua-13635	43	6	men	man	NOUN
aiua-13635	43	7	submitted	submit	VERB
aiua-13635	43	8	to	to	ADP
aiua-13635	43	9	ngs	ngs	PROPN
aiua-13635	43	10	brca	brca	PROPN
aiua-13635	43	11	evaluation	evaluation	NOUN
aiua-13635	43	12	.	.	PUNCT
aiua-13635	44	1	overall	overall	ADJ
aiua-13635	44	2	patients	patient	NOUN
aiua-13635	44	3	’	'	PUNCT
aiua-13635	44	4	characteristics	characteristic	NOUN
aiua-13635	44	5	(	(	PUNCT
aiua-13635	44	6	tot	tot	NOUN
aiua-13635	44	7	.	.	PUNCT
aiua-13635	45	1	n	n	NOUN
aiua-13635	45	2	=	=	NOUN
aiua-13635	45	3	52	52	NUM
aiua-13635	45	4	)	)	PUNCT
aiua-13635	45	5	age	age	NOUN
aiua-13635	45	6	(	(	PUNCT
aiua-13635	45	7	years	year	NOUN
aiua-13635	45	8	)	)	PUNCT
aiua-13635	45	9	range	range	VERB
aiua-13635	45	10	52	52	NUM
aiua-13635	45	11	-	-	SYM
aiua-13635	45	12	97	97	NUM
aiua-13635	45	13	median	median	NOUN
aiua-13635	45	14	73	73	NUM
aiua-13635	45	15	cancer	cancer	NOUN
aiua-13635	45	16	family	family	NOUN
aiua-13635	45	17	history	history	NOUN
aiua-13635	45	18	in	in	ADP
aiua-13635	45	19	a	a	DET
aiua-13635	45	20	first	first	ADJ
aiua-13635	45	21	degree	degree	NOUN
aiua-13635	45	22	realtive	realtive	ADJ
aiua-13635	45	23	range	range	NOUN
aiua-13635	45	24	52	52	NUM
aiua-13635	45	25	-	-	SYM
aiua-13635	45	26	97	97	NUM
aiua-13635	45	27	median	median	NOUN
aiua-13635	45	28	73	73	NUM
aiua-13635	45	29	gleason	gleason	NOUN
aiua-13635	45	30	score	score	VERB
aiua-13635	45	31	≤	≤	NUM
aiua-13635	45	32	7	7	NUM
aiua-13635	45	33	15	15	NUM
aiua-13635	45	34	≥	≥	NOUN
aiua-13635	45	35	8	8	NUM
aiua-13635	45	36	37	37	NUM
aiua-13635	45	37	metastasis	metastasis	NOUN
aiua-13635	45	38	at	at	ADP
aiua-13635	45	39	diagnosis	diagnosis	NOUN
aiua-13635	45	40	(	(	PUNCT
aiua-13635	46	1	locally	locally	ADV
aiua-13635	46	2	advanced	advanced	ADJ
aiua-13635	46	3	)	)	PUNCT
aiua-13635	46	4	28	28	NUM
aiua-13635	47	1	metastatic	metastatic	NOUN
aiua-13635	47	2	setting	set	VERB
aiua-13635	47	3	24	24	NUM
aiua-13635	47	4	brca	brca	NUM
aiua-13635	47	5	mutated	mutate	VERB
aiua-13635	47	6	10	10	NUM
aiua-13635	47	7	wild	wild	ADJ
aiua-13635	47	8	-	-	PUNCT
aiua-13635	47	9	type	type	NOUN
aiua-13635	47	10	42	42	NUM
aiua-13635	47	11	castration	castration	NOUN
aiua-13635	47	12	resistance	resistance	NOUN
aiua-13635	48	1	yes	yes	INTJ
aiua-13635	48	2	20	20	NUM
aiua-13635	49	1	no	no	DET
aiua-13635	49	2	32	32	NUM
aiua-13635	49	3	table	table	NOUN
aiua-13635	49	4	2	2	NUM
aiua-13635	49	5	.	.	PUNCT
aiua-13635	49	6	brca	brca	PROPN
aiua-13635	49	7	mutations	mutation	NOUN
aiua-13635	49	8	(	(	PUNCT
aiua-13635	49	9	somatic	somatic	ADJ
aiua-13635	49	10	and/or	and/or	CCONJ
aiua-13635	49	11	germline	germline	NOUN
aiua-13635	49	12	)	)	PUNCT
aiua-13635	49	13	in	in	ADP
aiua-13635	49	14	10/52	10/52	NUM
aiua-13635	49	15	(	(	PUNCT
aiua-13635	49	16	19.2	19.2	NUM
aiua-13635	49	17	%	%	NOUN
aiua-13635	49	18	)	)	PUNCT
aiua-13635	49	19	patients	patient	NOUN
aiua-13635	49	20	with	with	ADP
aiua-13635	49	21	aggressiveness	aggressiveness	NOUN
aiua-13635	49	22	prostate	prostate	NOUN
aiua-13635	49	23	cancer	cancer	NOUN
aiua-13635	49	24	.	.	PUNCT
aiua-13635	50	1	archivio	archivio	NOUN
aiua-13635	50	2	italiano	italiano	PROPN
aiua-13635	50	3	di	di	PROPN
aiua-13635	50	4	urologia	urologia	PROPN
aiua-13635	50	5	e	e	PROPN
aiua-13635	50	6	andrologia	andrologia	NOUN
aiua-13635	50	7	2025	2025	NUM
aiua-13635	50	8	;	;	PUNCT
aiua-13635	50	9	97(2):13635	97(2):13635	NUM
aiua-13635	50	10	3	3	NUM
aiua-13635	50	11	prostate	prostate	NOUN
aiua-13635	50	12	cancer	cancer	NOUN
aiua-13635	50	13	and	and	CCONJ
aiua-13635	50	14	brca	brca	PROPN
aiua-13635	50	15	mutations	mutation	NOUN
aiua-13635	50	16	criteria	criterion	NOUN
aiua-13635	50	17	of	of	ADP
aiua-13635	50	18	20.8	20.8	NUM
aiua-13635	50	19	%	%	NOUN
aiua-13635	50	20	in	in	ADP
aiua-13635	50	21	197	197	NUM
aiua-13635	50	22	cases	case	NOUN
aiua-13635	50	23	of	of	ADP
aiua-13635	50	24	primary	primary	ADJ
aiua-13635	50	25	and	and	CCONJ
aiua-13635	50	26	metastatic	metastatic	ADJ
aiua-13635	50	27	pca	pca	PROPN
aiua-13635	50	28	.	.	PUNCT
aiua-13635	51	1	the	the	DET
aiua-13635	51	2	inclusion	inclusion	NOUN
aiua-13635	51	3	of	of	ADP
aiua-13635	51	4	genomic	genomic	NOUN
aiua-13635	51	5	testing	testing	NOUN
aiua-13635	51	6	based	base	VERB
aiua-13635	51	7	on	on	ADP
aiua-13635	51	8	ffpe	ffpe	NOUN
aiua-13635	51	9	samples	sample	NOUN
aiua-13635	51	10	for	for	ADP
aiua-13635	51	11	predictive	predictive	ADJ
aiua-13635	51	12	purposes	purpose	NOUN
aiua-13635	51	13	in	in	ADP
aiua-13635	51	14	the	the	DET
aiua-13635	51	15	management	management	NOUN
aiua-13635	51	16	of	of	ADP
aiua-13635	51	17	patients	patient	NOUN
aiua-13635	51	18	with	with	ADP
aiua-13635	51	19	metastatic	metastatic	ADJ
aiua-13635	51	20	pca	pca	NOUN
aiua-13635	51	21	has	have	VERB
aiua-13635	51	22	relevant	relevant	ADJ
aiua-13635	51	23	implications	implication	NOUN
aiua-13635	51	24	for	for	ADP
aiua-13635	51	25	their	their	PRON
aiua-13635	51	26	healthy	healthy	ADJ
aiua-13635	51	27	relatives	relative	NOUN
aiua-13635	51	28	in	in	ADP
aiua-13635	51	29	the	the	DET
aiua-13635	51	30	presence	presence	NOUN
aiua-13635	51	31	of	of	ADP
aiua-13635	51	32	germline	germline	NOUN
aiua-13635	51	33	mutations	mutation	NOUN
aiua-13635	51	34	.	.	PUNCT
aiua-13635	52	1	it	it	PRON
aiua-13635	52	2	also	also	ADV
aiua-13635	52	3	offers	offer	VERB
aiua-13635	52	4	the	the	DET
aiua-13635	52	5	real	real	ADJ
aiua-13635	52	6	possibility	possibility	NOUN
aiua-13635	52	7	of	of	ADP
aiua-13635	52	8	preventing	prevent	VERB
aiua-13635	52	9	cancer	cancer	NOUN
aiua-13635	52	10	in	in	ADP
aiua-13635	52	11	brca1/2	brca1/2	ADJ
aiua-13635	52	12	mutation	mutation	NOUN
aiua-13635	52	13	carriers	carrier	NOUN
aiua-13635	52	14	through	through	ADP
aiua-13635	52	15	screening	screen	VERB
aiua-13635	52	16	protocols	protocol	NOUN
aiua-13635	52	17	(	(	PUNCT
aiua-13635	52	18	29	29	NUM
aiua-13635	52	19	)	)	PUNCT
aiua-13635	52	20	.	.	PUNCT
aiua-13635	53	1	men	man	NOUN
aiua-13635	53	2	with	with	ADP
aiua-13635	53	3	brca1	brca1	PROPN
aiua-13635	53	4	/	/	SYM
aiua-13635	53	5	brca2	brca2	PROPN
aiua-13635	53	6	germline	germline	NOUN
aiua-13635	53	7	mutations	mutation	NOUN
aiua-13635	53	8	who	who	PRON
aiua-13635	53	9	are	be	AUX
aiua-13635	53	10	on	on	ADP
aiua-13635	53	11	active	active	ADJ
aiua-13635	53	12	surveillance	surveillance	NOUN
aiua-13635	53	13	for	for	ADP
aiua-13635	53	14	low	low	ADJ
aiua-13635	53	15	-	-	PUNCT
aiua-13635	53	16	risk	risk	NOUN
aiua-13635	53	17	pca	pca	NOUN
aiua-13635	53	18	have	have	AUX
aiua-13635	53	19	been	be	AUX
aiua-13635	53	20	reported	report	VERB
aiua-13635	53	21	to	to	PART
aiua-13635	53	22	be	be	AUX
aiua-13635	53	23	at	at	ADP
aiua-13635	53	24	higher	high	ADJ
aiua-13635	53	25	risk	risk	NOUN
aiua-13635	53	26	of	of	ADP
aiua-13635	53	27	reclassification	reclassification	NOUN
aiua-13635	53	28	than	than	ADP
aiua-13635	53	29	noncarriers	noncarrier	NOUN
aiua-13635	53	30	(	(	PUNCT
aiua-13635	53	31	30	30	NUM
aiua-13635	53	32	)	)	PUNCT
aiua-13635	53	33	;	;	PUNCT
aiua-13635	53	34	in	in	ADP
aiua-13635	53	35	these	these	DET
aiua-13635	53	36	cases	case	NOUN
aiua-13635	53	37	,	,	PUNCT
aiua-13635	53	38	closer	close	ADJ
aiua-13635	53	39	surveillance	surveillance	NOUN
aiua-13635	53	40	incorporating	incorporate	VERB
aiua-13635	53	41	other	other	ADJ
aiua-13635	53	42	clinical	clinical	ADJ
aiua-13635	53	43	parameters	parameter	NOUN
aiua-13635	53	44	may	may	AUX
aiua-13635	53	45	be	be	AUX
aiua-13635	53	46	recommended	recommend	VERB
aiua-13635	53	47	(	(	PUNCT
aiua-13635	53	48	31	31	NUM
aiua-13635	53	49	-	-	SYM
aiua-13635	53	50	33	33	NUM
aiua-13635	53	51	)	)	PUNCT
aiua-13635	53	52	.	.	PUNCT
aiua-13635	54	1	the	the	DET
aiua-13635	54	2	european	european	PROPN
aiua-13635	54	3	urological	urological	PROPN
aiua-13635	54	4	association	association	PROPN
aiua-13635	54	5	(	(	PUNCT
aiua-13635	54	6	34	34	NUM
aiua-13635	54	7	)	)	PUNCT
aiua-13635	54	8	recommends	recommend	VERB
aiua-13635	54	9	starting	start	VERB
aiua-13635	54	10	pca	pca	NOUN
aiua-13635	54	11	screening	screening	NOUN
aiua-13635	54	12	at	at	ADP
aiua-13635	54	13	the	the	DET
aiua-13635	54	14	age	age	NOUN
aiua-13635	54	15	of	of	ADP
aiua-13635	54	16	40	40	NUM
aiua-13635	54	17	for	for	ADP
aiua-13635	54	18	male	male	ADJ
aiua-13635	54	19	brca2	brca2	NOUN
aiua-13635	54	20	carriers	carrier	NOUN
aiua-13635	54	21	.	.	PUNCT
aiua-13635	55	1	the	the	DET
aiua-13635	55	2	national	national	ADJ
aiua-13635	55	3	comprehensive	comprehensive	ADJ
aiua-13635	55	4	cancer	cancer	NOUN
aiua-13635	55	5	network	network	NOUN
aiua-13635	55	6	(	(	PUNCT
aiua-13635	55	7	nccn	nccn	ADJ
aiua-13635	55	8	)	)	PUNCT
aiua-13635	55	9	guidelines	guideline	NOUN
aiua-13635	55	10	do	do	VERB
aiua-13635	55	11	the	the	DET
aiua-13635	55	12	same	same	ADJ
aiua-13635	55	13	for	for	ADP
aiua-13635	55	14	brca1	brca1	NOUN
aiua-13635	55	15	carriers	carrier	NOUN
aiua-13635	55	16	and	and	CCONJ
aiua-13635	55	17	routinely	routinely	ADV
aiua-13635	55	18	perform	perform	VERB
aiua-13635	55	19	brca1/2	brca1/2	ADJ
aiua-13635	55	20	testing	testing	NOUN
aiua-13635	55	21	for	for	ADP
aiua-13635	55	22	men	man	NOUN
aiua-13635	55	23	with	with	ADP
aiua-13635	55	24	highrisk	highrisk	NOUN
aiua-13635	55	25	pca	pca	PROPN
aiua-13635	55	26	(	(	PUNCT
aiua-13635	55	27	gleason	gleason	PROPN
aiua-13635	55	28	score	score	VERB
aiua-13635	55	29	>	>	X
aiua-13635	55	30	8)	8)	NUM
aiua-13635	55	31	,	,	PUNCT
aiua-13635	55	32	ductal	ductal	ADJ
aiua-13635	55	33	or	or	CCONJ
aiua-13635	55	34	cribriform	cribriform	NOUN
aiua-13635	55	35	pca	pca	NOUN
aiua-13635	55	36	and	and	CCONJ
aiua-13635	55	37	metastatic	metastatic	ADJ
aiua-13635	55	38	disease	disease	NOUN
aiua-13635	55	39	(	(	PUNCT
aiua-13635	55	40	35	35	NUM
aiua-13635	55	41	)	)	PUNCT
aiua-13635	55	42	.	.	PUNCT
aiua-13635	56	1	t	t	NOUN
aiua-13635	56	2	-	-	PUNCT
aiua-13635	56	3	ngs	ng	NOUN
aiua-13635	56	4	analysis	analysis	NOUN
aiua-13635	56	5	for	for	ADP
aiua-13635	56	6	brca	brca	PROPN
aiua-13635	56	7	genetic	genetic	ADJ
aiua-13635	56	8	testing	testing	NOUN
aiua-13635	56	9	using	use	VERB
aiua-13635	56	10	ffpe	ffpe	ADJ
aiua-13635	56	11	tissue	tissue	NOUN
aiua-13635	56	12	in	in	ADP
aiua-13635	56	13	the	the	DET
aiua-13635	56	14	clinical	clinical	ADJ
aiua-13635	56	15	setting	setting	NOUN
aiua-13635	56	16	of	of	ADP
aiua-13635	56	17	patients	patient	NOUN
aiua-13635	56	18	with	with	ADP
aiua-13635	56	19	metastatic	metastatic	ADJ
aiua-13635	56	20	pca	pca	NOUN
aiua-13635	56	21	appears	appear	VERB
aiua-13635	56	22	to	to	PART
aiua-13635	56	23	be	be	AUX
aiua-13635	56	24	a	a	DET
aiua-13635	56	25	valuable	valuable	ADJ
aiua-13635	56	26	tool	tool	NOUN
aiua-13635	56	27	,	,	PUNCT
aiua-13635	56	28	not	not	PART
aiua-13635	56	29	only	only	ADV
aiua-13635	56	30	for	for	ADP
aiua-13635	56	31	therapeutic	therapeutic	ADJ
aiua-13635	56	32	purposes	purpose	NOUN
aiua-13635	56	33	,	,	PUNCT
aiua-13635	56	34	but	but	CCONJ
aiua-13635	56	35	also	also	ADV
aiua-13635	56	36	to	to	PART
aiua-13635	56	37	identify	identify	VERB
aiua-13635	56	38	families	family	NOUN
aiua-13635	56	39	with	with	ADP
aiua-13635	56	40	genetic	genetic	ADJ
aiua-13635	56	41	predisposition	predisposition	NOUN
aiua-13635	56	42	who	who	PRON
aiua-13635	56	43	may	may	AUX
aiua-13635	56	44	be	be	AUX
aiua-13635	56	45	underdiagnosed	underdiagnose	VERB
aiua-13635	56	46	by	by	ADP
aiua-13635	56	47	canonical	canonical	ADJ
aiua-13635	56	48	criteria	criterion	NOUN
aiua-13635	56	49	.	.	PUNCT
aiua-13635	57	1	the	the	DET
aiua-13635	57	2	impact	impact	NOUN
aiua-13635	57	3	study	study	NOUN
aiua-13635	57	4	(	(	PUNCT
aiua-13635	57	5	13	13	NUM
aiua-13635	57	6	)	)	PUNCT
aiua-13635	57	7	investigated	investigate	VERB
aiua-13635	57	8	targeted	target	VERB
aiua-13635	57	9	pca	pca	NOUN
aiua-13635	57	10	screening	screening	NOUN
aiua-13635	57	11	in	in	ADP
aiua-13635	57	12	men	man	NOUN
aiua-13635	57	13	with	with	ADP
aiua-13635	57	14	germline	germline	NOUN
aiua-13635	57	15	brca1/2	brca1/2	ADJ
aiua-13635	57	16	mutations	mutation	NOUN
aiua-13635	57	17	;	;	PUNCT
aiua-13635	57	18	among	among	ADP
aiua-13635	57	19	the	the	DET
aiua-13635	57	20	357	357	NUM
aiua-13635	57	21	men	man	NOUN
aiua-13635	57	22	who	who	PRON
aiua-13635	57	23	underwent	undergo	VERB
aiua-13635	57	24	prostate	prostate	NOUN
aiua-13635	57	25	biopsy	biopsy	NOUN
aiua-13635	57	26	,	,	PUNCT
aiua-13635	57	27	the	the	DET
aiua-13635	57	28	112	112	NUM
aiua-13635	57	29	men	man	NOUN
aiua-13635	57	30	with	with	ADP
aiua-13635	57	31	pca	pca	PROPN
aiua-13635	57	32	were	be	AUX
aiua-13635	57	33	found	find	VERB
aiua-13635	57	34	to	to	PART
aiua-13635	57	35	have	have	VERB
aiua-13635	57	36	a	a	DET
aiua-13635	57	37	higher	high	ADJ
aiua-13635	57	38	detection	detection	NOUN
aiua-13635	57	39	rate	rate	NOUN
aiua-13635	57	40	in	in	ADP
aiua-13635	57	41	brca2	brca2	NOUN
aiua-13635	57	42	carriers	carrier	NOUN
aiua-13635	57	43	compared	compare	VERB
aiua-13635	57	44	to	to	ADP
aiua-13635	57	45	non	non	NOUN
aiua-13635	57	46	-	-	NOUN
aiua-13635	57	47	carriers	carrier	NOUN
aiua-13635	57	48	(	(	PUNCT
aiua-13635	57	49	73	73	NUM
aiua-13635	57	50	%	%	NOUN
aiua-13635	57	51	versus	versus	ADP
aiua-13635	57	52	60	60	NUM
aiua-13635	57	53	%	%	NOUN
aiua-13635	57	54	)	)	PUNCT
aiua-13635	57	55	.	.	PUNCT
aiua-13635	58	1	in	in	ADP
aiua-13635	58	2	addition	addition	NOUN
aiua-13635	58	3	,	,	PUNCT
aiua-13635	58	4	brca2	brca2	PROPN
aiua-13635	58	5	carriers	carrier	NOUN
aiua-13635	58	6	were	be	AUX
aiua-13635	58	7	diagnosed	diagnose	VERB
aiua-13635	58	8	at	at	ADP
aiua-13635	58	9	a	a	DET
aiua-13635	58	10	younger	young	ADJ
aiua-13635	58	11	age	age	NOUN
aiua-13635	58	12	and	and	CCONJ
aiua-13635	58	13	were	be	AUX
aiua-13635	58	14	more	more	ADV
aiua-13635	58	15	likely	likely	ADJ
aiua-13635	58	16	to	to	PART
aiua-13635	58	17	have	have	VERB
aiua-13635	58	18	cspca	cspca	NOUN
aiua-13635	58	19	than	than	ADP
aiua-13635	58	20	brca2	brca2	PROPN
aiua-13635	58	21	non	non	ADJ
aiua-13635	58	22	-	-	NOUN
aiua-13635	58	23	carriers	carrier	NOUN
aiua-13635	58	24	(	(	PUNCT
aiua-13635	58	25	77	77	NUM
aiua-13635	58	26	vs	vs	ADP
aiua-13635	58	27	40	40	NUM
aiua-13635	58	28	%	%	NOUN
aiua-13635	58	29	)	)	PUNCT
aiua-13635	58	30	.	.	PUNCT
aiua-13635	59	1	in	in	ADP
aiua-13635	59	2	contrast	contrast	NOUN
aiua-13635	59	3	,	,	PUNCT
aiua-13635	59	4	no	no	DET
aiua-13635	59	5	differences	difference	NOUN
aiua-13635	59	6	were	be	AUX
aiua-13635	59	7	found	find	VERB
aiua-13635	59	8	between	between	ADP
aiua-13635	59	9	brca1	brca1	PROPN
aiua-13635	59	10	carriers	carrier	NOUN
aiua-13635	59	11	and	and	CCONJ
aiua-13635	59	12	brca1	brca1	PROPN
aiua-13635	59	13	non	non	PROPN
aiua-13635	59	14	-	-	NOUN
aiua-13635	59	15	carriers	carrier	NOUN
aiua-13635	59	16	in	in	ADP
aiua-13635	59	17	terms	term	NOUN
aiua-13635	59	18	of	of	ADP
aiua-13635	59	19	age	age	NOUN
aiua-13635	59	20	or	or	CCONJ
aiua-13635	59	21	tumour	tumour	NOUN
aiua-13635	59	22	characteristics	characteristic	NOUN
aiua-13635	59	23	.	.	PUNCT
aiua-13635	60	1	the	the	DET
aiua-13635	60	2	ability	ability	NOUN
aiua-13635	60	3	to	to	PART
aiua-13635	60	4	test	test	VERB
aiua-13635	60	5	brca1/2	brca1/2	ADJ
aiua-13635	60	6	genes	gene	NOUN
aiua-13635	60	7	from	from	ADP
aiua-13635	60	8	ffpe	ffpe	ADJ
aiua-13635	60	9	samples	sample	NOUN
aiua-13635	60	10	would	would	AUX
aiua-13635	60	11	allow	allow	VERB
aiua-13635	60	12	the	the	DET
aiua-13635	60	13	simultaneous	simultaneous	ADJ
aiua-13635	60	14	assessment	assessment	NOUN
aiua-13635	60	15	of	of	ADP
aiua-13635	60	16	both	both	CCONJ
aiua-13635	60	17	somatic	somatic	ADJ
aiua-13635	60	18	and	and	CCONJ
aiua-13635	60	19	germline	germline	NOUN
aiua-13635	60	20	mutations	mutation	NOUN
aiua-13635	60	21	using	use	VERB
aiua-13635	60	22	an	an	DET
aiua-13635	60	23	accessible	accessible	ADJ
aiua-13635	60	24	material	material	NOUN
aiua-13635	60	25	that	that	PRON
aiua-13635	60	26	is	be	AUX
aiua-13635	60	27	routinely	routinely	ADV
aiua-13635	60	28	available	available	ADJ
aiua-13635	60	29	in	in	ADP
aiua-13635	60	30	any	any	DET
aiua-13635	60	31	pathology	pathology	NOUN
aiua-13635	60	32	laboratory	laboratory	NOUN
aiua-13635	60	33	(	(	PUNCT
aiua-13635	60	34	36	36	NUM
aiua-13635	60	35	)	)	PUNCT
aiua-13635	60	36	.	.	PUNCT
aiua-13635	61	1	therefore	therefore	ADV
aiua-13635	61	2	,	,	PUNCT
aiua-13635	61	3	there	there	PRON
aiua-13635	61	4	is	be	VERB
aiua-13635	61	5	a	a	DET
aiua-13635	61	6	need	need	NOUN
aiua-13635	61	7	for	for	ADP
aiua-13635	61	8	efficient	efficient	ADJ
aiua-13635	61	9	and	and	CCONJ
aiua-13635	61	10	timely	timely	ADJ
aiua-13635	61	11	methods	method	NOUN
aiua-13635	61	12	to	to	PART
aiua-13635	61	13	detect	detect	VERB
aiua-13635	61	14	both	both	PRON
aiua-13635	61	15	somatic	somatic	ADJ
aiua-13635	61	16	and	and	CCONJ
aiua-13635	61	17	germline	germline	NOUN
aiua-13635	61	18	mutations	mutation	NOUN
aiua-13635	61	19	starting	start	VERB
aiua-13635	61	20	from	from	ADP
aiua-13635	61	21	ffpe	ffpe	ADJ
aiua-13635	61	22	tissue	tissue	NOUN
aiua-13635	61	23	under	under	ADP
aiua-13635	61	24	expert	expert	NOUN
aiua-13635	61	25	guidance	guidance	NOUN
aiua-13635	61	26	,	,	PUNCT
aiua-13635	61	27	considering	consider	VERB
aiua-13635	61	28	the	the	DET
aiua-13635	61	29	high	high	ADJ
aiua-13635	61	30	percentage	percentage	NOUN
aiua-13635	61	31	of	of	ADP
aiua-13635	61	32	failures	failure	NOUN
aiua-13635	61	33	in	in	ADP
aiua-13635	61	34	this	this	DET
aiua-13635	61	35	tumour	tumour	NOUN
aiua-13635	61	36	setting	setting	NOUN
aiua-13635	61	37	(	(	PUNCT
aiua-13635	61	38	37	37	NUM
aiua-13635	61	39	)	)	PUNCT
aiua-13635	61	40	.	.	PUNCT
aiua-13635	62	1	recently	recently	ADV
aiua-13635	62	2	,	,	PUNCT
aiua-13635	62	3	a	a	DET
aiua-13635	62	4	consensus	consensus	NOUN
aiua-13635	62	5	paper	paper	NOUN
aiua-13635	62	6	was	be	AUX
aiua-13635	62	7	developed	develop	VERB
aiua-13635	62	8	and	and	CCONJ
aiua-13635	62	9	approved	approve	VERB
aiua-13635	62	10	by	by	ADP
aiua-13635	62	11	a	a	DET
aiua-13635	62	12	multidisciplinary	multidisciplinary	ADJ
aiua-13635	62	13	expert	expert	NOUN
aiua-13635	62	14	panel	panel	NOUN
aiua-13635	62	15	on	on	ADP
aiua-13635	62	16	behalf	behalf	NOUN
aiua-13635	62	17	of	of	ADP
aiua-13635	62	18	the	the	DET
aiua-13635	62	19	italian	italian	ADJ
aiua-13635	62	20	scientific	scientific	ADJ
aiua-13635	62	21	societies	society	NOUN
aiua-13635	62	22	(	(	PUNCT
aiua-13635	62	23	38	38	NUM
aiua-13635	62	24	)	)	PUNCT
aiua-13635	62	25	to	to	PART
aiua-13635	62	26	improve	improve	VERB
aiua-13635	62	27	accurate	accurate	ADJ
aiua-13635	62	28	patient	patient	NOUN
aiua-13635	62	29	selection	selection	NOUN
aiua-13635	62	30	by	by	ADP
aiua-13635	62	31	the	the	DET
aiua-13635	62	32	use	use	NOUN
aiua-13635	62	33	of	of	ADP
aiua-13635	62	34	standardized	standardized	ADJ
aiua-13635	62	35	and	and	CCONJ
aiua-13635	62	36	harmonized	harmonized	ADJ
aiua-13635	62	37	procedures	procedure	NOUN
aiua-13635	62	38	and	and	CCONJ
aiua-13635	62	39	adherence	adherence	NOUN
aiua-13635	62	40	to	to	ADP
aiua-13635	62	41	homogeneous	homogeneous	ADJ
aiua-13635	62	42	brca	brca	PROPN
aiua-13635	62	43	testing	testing	NOUN
aiua-13635	62	44	criteria	criterion	NOUN
aiua-13635	62	45	.	.	PUNCT
aiua-13635	63	1	loeb	loeb	PROPN
aiua-13635	63	2	et	et	PROPN
aiua-13635	63	3	al	al	PROPN
aiua-13635	63	4	.	.	PROPN
aiua-13635	64	1	(	(	PUNCT
aiua-13635	64	2	39	39	NUM
aiua-13635	64	3	)	)	PUNCT
aiua-13635	64	4	reported	report	VERB
aiua-13635	64	5	on	on	ADP
aiua-13635	64	6	a	a	DET
aiua-13635	64	7	survey	survey	NOUN
aiua-13635	64	8	of	of	ADP
aiua-13635	64	9	urologists	urologist	NOUN
aiua-13635	64	10	in	in	ADP
aiua-13635	64	11	the	the	DET
aiua-13635	64	12	usa	usa	PROPN
aiua-13635	64	13	that	that	PRON
aiua-13635	64	14	examined	examine	VERB
aiua-13635	64	15	knowledge	knowledge	NOUN
aiua-13635	64	16	of	of	ADP
aiua-13635	64	17	germline	germline	NOUN
aiua-13635	64	18	testing	testing	NOUN
aiua-13635	64	19	guidelines	guideline	NOUN
aiua-13635	64	20	and	and	CCONJ
aiua-13635	64	21	practice	practice	NOUN
aiua-13635	64	22	patterns	pattern	NOUN
aiua-13635	64	23	.	.	PUNCT
aiua-13635	65	1	of	of	ADP
aiua-13635	65	2	a	a	DET
aiua-13635	65	3	total	total	NOUN
aiua-13635	65	4	of	of	ADP
aiua-13635	65	5	132	132	NUM
aiua-13635	65	6	respondents	respondent	NOUN
aiua-13635	65	7	from	from	ADP
aiua-13635	65	8	different	different	ADJ
aiua-13635	65	9	practices	practice	NOUN
aiua-13635	65	10	,	,	PUNCT
aiua-13635	65	11	12	12	NUM
aiua-13635	65	12	%	%	NOUN
aiua-13635	65	13	performed	perform	VERB
aiua-13635	65	14	germline	germline	NOUN
aiua-13635	65	15	testing	testing	NOUN
aiua-13635	65	16	,	,	PUNCT
aiua-13635	65	17	44	44	NUM
aiua-13635	65	18	%	%	NOUN
aiua-13635	65	19	refer	refer	VERB
aiua-13635	65	20	to	to	ADP
aiua-13635	65	21	a	a	DET
aiua-13635	65	22	genetic	genetic	ADJ
aiua-13635	65	23	counsellor	counsellor	NOUN
aiua-13635	65	24	,	,	PUNCT
aiua-13635	65	25	11	11	NUM
aiua-13635	65	26	%	%	NOUN
aiua-13635	65	27	do	do	AUX
aiua-13635	65	28	both	both	PRON
aiua-13635	65	29	and	and	CCONJ
aiua-13635	65	30	33	33	NUM
aiua-13635	65	31	%	%	NOUN
aiua-13635	65	32	do	do	AUX
aiua-13635	65	33	not	not	PART
aiua-13635	65	34	test	test	VERB
aiua-13635	65	35	/	/	SYM
aiua-13635	65	36	refer	refer	NOUN
aiua-13635	65	37	,	,	PUNCT
aiua-13635	65	38	4	4	NUM
aiua-13635	65	39	%	%	NOUN
aiua-13635	65	40	had	have	VERB
aiua-13635	65	41	formal	formal	ADJ
aiua-13635	65	42	training	training	NOUN
aiua-13635	65	43	in	in	ADP
aiua-13635	65	44	genetics	genetic	NOUN
aiua-13635	65	45	,	,	PUNCT
aiua-13635	65	46	suggesting	suggest	VERB
aiua-13635	65	47	that	that	SCONJ
aiua-13635	65	48	there	there	PRON
aiua-13635	65	49	are	be	VERB
aiua-13635	65	50	significant	significant	ADJ
aiua-13635	65	51	gaps	gap	NOUN
aiua-13635	65	52	in	in	ADP
aiua-13635	65	53	urologists	urologist	NOUN
aiua-13635	65	54	'	'	PART
aiua-13635	65	55	knowledge	knowledge	NOUN
aiua-13635	65	56	of	of	ADP
aiua-13635	65	57	germline	germline	NOUN
aiua-13635	65	58	testing	testing	NOUN
aiua-13635	65	59	and	and	CCONJ
aiua-13635	65	60	how	how	SCONJ
aiua-13635	65	61	to	to	PART
aiua-13635	65	62	align	align	VERB
aiua-13635	65	63	practice	practice	NOUN
aiua-13635	65	64	with	with	ADP
aiua-13635	65	65	national	national	ADJ
aiua-13635	65	66	guidelines	guideline	NOUN
aiua-13635	65	67	.	.	PUNCT
aiua-13635	66	1	although	although	SCONJ
aiua-13635	66	2	somatic	somatic	ADJ
aiua-13635	66	3	and	and	CCONJ
aiua-13635	66	4	germline	germline	NOUN
aiua-13635	66	5	brca2	brca2	PROPN
aiua-13635	66	6	testing	testing	NOUN
aiua-13635	66	7	is	be	AUX
aiua-13635	66	8	only	only	ADV
aiua-13635	66	9	recommended	recommend	VERB
aiua-13635	66	10	in	in	ADP
aiua-13635	66	11	men	man	NOUN
aiua-13635	66	12	with	with	ADP
aiua-13635	66	13	metastatic	metastatic	ADJ
aiua-13635	66	14	castration	castration	NOUN
aiua-13635	66	15	-	-	PUNCT
aiua-13635	66	16	resistant	resistant	ADJ
aiua-13635	66	17	pca	pca	NOUN
aiua-13635	66	18	,	,	PUNCT
aiua-13635	66	19	the	the	DET
aiua-13635	66	20	possibility	possibility	NOUN
aiua-13635	66	21	of	of	ADP
aiua-13635	66	22	also	also	ADV
aiua-13635	66	23	performing	perform	VERB
aiua-13635	66	24	the	the	DET
aiua-13635	66	25	test	test	NOUN
aiua-13635	66	26	in	in	ADP
aiua-13635	66	27	men	man	NOUN
aiua-13635	66	28	with	with	ADP
aiua-13635	66	29	locally	locally	ADV
aiua-13635	66	30	advanced	advanced	ADJ
aiua-13635	66	31	and/or	and/or	CCONJ
aiua-13635	66	32	aggressive	aggressive	ADJ
aiua-13635	66	33	pca	pca	NOUN
aiua-13635	66	34	,	,	PUNCT
aiua-13635	66	35	as	as	SCONJ
aiua-13635	66	36	suggested	suggest	VERB
aiua-13635	66	37	in	in	ADP
aiua-13635	66	38	the	the	DET
aiua-13635	66	39	nccn	nccn	ADJ
aiua-13635	66	40	guidelines	guideline	NOUN
aiua-13635	66	41	,	,	PUNCT
aiua-13635	66	42	offers	offer	VERB
aiua-13635	66	43	the	the	DET
aiua-13635	66	44	opportunity	opportunity	NOUN
aiua-13635	66	45	to	to	PART
aiua-13635	66	46	figure	figure	VERB
aiua-13635	66	47	1	1	NUM
aiua-13635	66	48	.	.	PUNCT
aiua-13635	66	49	family	family	NOUN
aiua-13635	66	50	evaluation	evaluation	NOUN
aiua-13635	66	51	in	in	ADP
aiua-13635	66	52	a	a	DET
aiua-13635	66	53	case	case	NOUN
aiua-13635	66	54	of	of	ADP
aiua-13635	66	55	brca	brca	PROPN
aiua-13635	66	56	germline	germline	PROPN
aiua-13635	66	57	mutation	mutation	NOUN
aiua-13635	66	58	.	.	PUNCT
aiua-13635	67	1	archivio	archivio	NOUN
aiua-13635	67	2	italiano	italiano	PROPN
aiua-13635	67	3	di	di	PROPN
aiua-13635	67	4	urologia	urologia	PROPN
aiua-13635	67	5	e	e	PROPN
aiua-13635	67	6	andrologia	andrologia	NOUN
aiua-13635	67	7	2025	2025	NUM
aiua-13635	67	8	;	;	PUNCT
aiua-13635	67	9	97(2):13635	97(2):13635	PROPN
aiua-13635	67	10	s.	s.	PROPN
aiua-13635	67	11	vatrano	vatrano	PROPN
aiua-13635	67	12	,	,	PUNCT
aiua-13635	67	13	p.	p.	PROPN
aiua-13635	67	14	pepe	pepe	PROPN
aiua-13635	67	15	,	,	PUNCT
aiua-13635	67	16	l.	l.	PROPN
aiua-13635	67	17	pepe	pepe	PROPN
aiua-13635	67	18	,	,	PUNCT
aiua-13635	67	19	et	et	PROPN
aiua-13635	67	20	al	al	PROPN
aiua-13635	67	21	.	.	PROPN
aiua-13635	67	22	4	4	NUM
aiua-13635	67	23	select	select	ADJ
aiua-13635	67	24	patients	patient	NOUN
aiua-13635	67	25	at	at	ADP
aiua-13635	67	26	high	high	ADJ
aiua-13635	67	27	risk	risk	NOUN
aiua-13635	67	28	of	of	ADP
aiua-13635	67	29	clinical	clinical	ADJ
aiua-13635	67	30	progression	progression	NOUN
aiua-13635	67	31	and	and	CCONJ
aiua-13635	67	32	to	to	PART
aiua-13635	67	33	perform	perform	VERB
aiua-13635	67	34	adequate	adequate	ADJ
aiua-13635	67	35	clinical	clinical	ADJ
aiua-13635	67	36	cancer	cancer	NOUN
aiua-13635	67	37	screening	screening	NOUN
aiua-13635	67	38	in	in	ADP
aiua-13635	67	39	family	family	NOUN
aiua-13635	67	40	members	member	NOUN
aiua-13635	67	41	with	with	ADP
aiua-13635	67	42	germline	germline	NOUN
aiua-13635	67	43	mutations	mutation	NOUN
aiua-13635	67	44	to	to	PART
aiua-13635	67	45	prevent	prevent	VERB
aiua-13635	67	46	aggressiveness	aggressiveness	NOUN
aiua-13635	67	47	and/or	and/or	CCONJ
aiua-13635	67	48	advanced	advanced	ADJ
aiua-13635	67	49	cancer	cancer	NOUN
aiua-13635	67	50	at	at	ADP
aiua-13635	67	51	diagnosis	diagnosis	NOUN
aiua-13635	67	52	.	.	PUNCT
aiua-13635	68	1	in	in	ADP
aiua-13635	68	2	addition	addition	NOUN
aiua-13635	68	3	,	,	PUNCT
aiua-13635	68	4	early	early	ADJ
aiua-13635	68	5	genetic	genetic	ADJ
aiua-13635	68	6	tissue	tissue	NOUN
aiua-13635	68	7	testing	testing	NOUN
aiua-13635	68	8	could	could	AUX
aiua-13635	68	9	reduce	reduce	VERB
aiua-13635	68	10	the	the	DET
aiua-13635	68	11	risk	risk	NOUN
aiua-13635	68	12	of	of	ADP
aiua-13635	68	13	nondiagnostic	nondiagnostic	ADJ
aiua-13635	68	14	tissue	tissue	NOUN
aiua-13635	68	15	patterns	pattern	NOUN
aiua-13635	68	16	that	that	PRON
aiua-13635	68	17	are	be	AUX
aiua-13635	68	18	useful	useful	ADJ
aiua-13635	68	19	for	for	ADP
aiua-13635	68	20	genetic	genetic	ADJ
aiua-13635	68	21	testing	testing	NOUN
aiua-13635	68	22	,	,	PUNCT
aiua-13635	68	23	especially	especially	ADV
aiua-13635	68	24	many	many	ADJ
aiua-13635	68	25	years	year	NOUN
aiua-13635	68	26	after	after	ADP
aiua-13635	68	27	diagnosis	diagnosis	NOUN
aiua-13635	68	28	of	of	ADP
aiua-13635	68	29	pca	pca	NOUN
aiua-13635	68	30	,	,	PUNCT
aiua-13635	68	31	as	as	ADV
aiua-13635	68	32	well	well	ADV
aiua-13635	68	33	as	as	ADP
aiua-13635	68	34	the	the	DET
aiua-13635	68	35	difficulty	difficulty	NOUN
aiua-13635	68	36	of	of	ADP
aiua-13635	68	37	performing	perform	VERB
aiua-13635	68	38	biopsies	biopsy	NOUN
aiua-13635	68	39	of	of	ADP
aiua-13635	68	40	metastases	metastasis	NOUN
aiua-13635	68	41	(	(	PUNCT
aiua-13635	68	42	i.e.	i.e.	X
aiua-13635	68	43	,	,	PUNCT
aiua-13635	68	44	bone	bone	NOUN
aiua-13635	68	45	,	,	PUNCT
aiua-13635	68	46	retroperitoneal	retroperitoneal	ADJ
aiua-13635	68	47	nodes	node	NOUN
aiua-13635	68	48	)	)	PUNCT
aiua-13635	68	49	(	(	PUNCT
aiua-13635	68	50	37	37	NUM
aiua-13635	68	51	)	)	PUNCT
aiua-13635	68	52	.	.	PUNCT
aiua-13635	69	1	definitely	definitely	ADV
aiua-13635	69	2	,	,	PUNCT
aiua-13635	69	3	the	the	DET
aiua-13635	69	4	role	role	NOUN
aiua-13635	69	5	of	of	ADP
aiua-13635	69	6	the	the	DET
aiua-13635	69	7	urologist	urologist	NOUN
aiua-13635	69	8	in	in	ADP
aiua-13635	69	9	a	a	DET
aiua-13635	69	10	multidisciplinary	multidisciplinary	ADJ
aiua-13635	69	11	approach	approach	NOUN
aiua-13635	69	12	is	be	AUX
aiua-13635	69	13	fundamental	fundamental	ADJ
aiua-13635	69	14	to	to	PART
aiua-13635	69	15	adequately	adequately	ADV
aiua-13635	69	16	inform	inform	VERB
aiua-13635	69	17	the	the	DET
aiua-13635	69	18	patient	patient	NOUN
aiua-13635	69	19	affected	affect	VERB
aiua-13635	69	20	by	by	ADP
aiua-13635	69	21	aggressive	aggressive	ADJ
aiua-13635	69	22	pca	pca	NOUN
aiua-13635	69	23	at	at	ADP
aiua-13635	69	24	the	the	DET
aiua-13635	69	25	time	time	NOUN
aiua-13635	69	26	of	of	ADP
aiua-13635	69	27	diagnosis	diagnosis	NOUN
aiua-13635	69	28	about	about	ADP
aiua-13635	69	29	the	the	DET
aiua-13635	69	30	role	role	NOUN
aiua-13635	69	31	of	of	ADP
aiua-13635	69	32	genetic	genetic	ADJ
aiua-13635	69	33	testing	testing	NOUN
aiua-13635	69	34	(	(	PUNCT
aiua-13635	69	35	somatic	somatic	ADJ
aiua-13635	69	36	and	and	CCONJ
aiua-13635	69	37	germline	germline	NOUN
aiua-13635	69	38	)	)	PUNCT
aiua-13635	69	39	to	to	PART
aiua-13635	69	40	improve	improve	VERB
aiua-13635	69	41	oncological	oncological	ADJ
aiua-13635	69	42	treatment	treatment	NOUN
aiua-13635	69	43	and	and	CCONJ
aiua-13635	69	44	prevent	prevent	VERB
aiua-13635	69	45	cancer	cancer	NOUN
aiua-13635	69	46	through	through	ADP
aiua-13635	69	47	early	early	ADJ
aiua-13635	69	48	screening	screen	VERB
aiua-13635	69	49	protocols	protocol	NOUN
aiua-13635	69	50	in	in	ADP
aiua-13635	69	51	family	family	NOUN
aiua-13635	69	52	members	member	NOUN
aiua-13635	69	53	with	with	ADP
aiua-13635	69	54	germline	germline	NOUN
aiua-13635	69	55	mutations	mutation	NOUN
aiua-13635	69	56	.	.	PUNCT
aiua-13635	70	1	these	these	DET
aiua-13635	70	2	data	datum	NOUN
aiua-13635	70	3	should	should	AUX
aiua-13635	70	4	be	be	AUX
aiua-13635	70	5	analyzed	analyze	VERB
aiua-13635	70	6	in	in	ADP
aiua-13635	70	7	a	a	DET
aiua-13635	70	8	larger	large	ADJ
aiua-13635	70	9	number	number	NOUN
aiua-13635	70	10	of	of	ADP
aiua-13635	70	11	patients	patient	NOUN
aiua-13635	70	12	and	and	CCONJ
aiua-13635	70	13	in	in	ADP
aiua-13635	70	14	a	a	DET
aiua-13635	70	15	multidisciplinary	multidisciplinary	ADJ
aiua-13635	70	16	team	team	NOUN
aiua-13635	70	17	to	to	PART
aiua-13635	70	18	assess	assess	VERB
aiua-13635	70	19	the	the	DET
aiua-13635	70	20	best	good	ADJ
aiua-13635	70	21	timing	timing	NOUN
aiua-13635	70	22	for	for	ADP
aiua-13635	70	23	brca	brca	PROPN
aiua-13635	70	24	testing	testing	PROPN
aiua-13635	70	25	,	,	PUNCT
aiua-13635	70	26	the	the	DET
aiua-13635	70	27	cost	cost	NOUN
aiua-13635	70	28	-	-	PUNCT
aiua-13635	70	29	effectiveness	effectiveness	NOUN
aiua-13635	70	30	and	and	CCONJ
aiua-13635	70	31	the	the	DET
aiua-13635	70	32	therapeutic	therapeutic	ADJ
aiua-13635	70	33	impact	impact	NOUN
aiua-13635	70	34	of	of	ADP
aiua-13635	70	35	early	early	ADJ
aiua-13635	70	36	genetic	genetic	ADJ
aiua-13635	70	37	analysis	analysis	NOUN
aiua-13635	70	38	.	.	PUNCT
aiua-13635	71	1	in	in	ADP
aiua-13635	71	2	our	our	PRON
aiua-13635	71	3	series	series	NOUN
aiua-13635	71	4	,	,	PUNCT
aiua-13635	71	5	3/7	3/7	NUM
aiua-13635	71	6	(	(	PUNCT
aiua-13635	71	7	43	43	NUM
aiua-13635	71	8	%	%	NOUN
aiua-13635	71	9	)	)	PUNCT
aiua-13635	71	10	patients	patient	NOUN
aiua-13635	71	11	with	with	ADP
aiua-13635	71	12	brca2	brca2	PROPN
aiua-13635	71	13	germline	germline	NOUN
aiua-13635	71	14	mutations	mutation	NOUN
aiua-13635	71	15	and	and	CCONJ
aiua-13635	71	16	negative	negative	ADJ
aiua-13635	71	17	family	family	NOUN
aiua-13635	71	18	history	history	NOUN
aiua-13635	71	19	for	for	ADP
aiua-13635	71	20	pca	pca	PROPN
aiua-13635	71	21	underwent	undergo	VERB
aiua-13635	71	22	genetic	genetic	ADJ
aiua-13635	71	23	counselling	counselling	NOUN
aiua-13635	71	24	,	,	PUNCT
aiua-13635	71	25	including	include	VERB
aiua-13635	71	26	family	family	NOUN
aiua-13635	71	27	members	member	NOUN
aiua-13635	71	28	,	,	PUNCT
aiua-13635	71	29	for	for	ADP
aiua-13635	71	30	appropriate	appropriate	ADJ
aiua-13635	71	31	oncological	oncological	ADJ
aiua-13635	71	32	screening	screening	NOUN
aiua-13635	71	33	.	.	PUNCT
aiua-13635	72	1	conclusions	conclusion	NOUN
aiua-13635	72	2	ngs	ng	VERB
aiua-13635	72	3	analysis	analysis	NOUN
aiua-13635	72	4	for	for	ADP
aiua-13635	72	5	brca	brca	PROPN
aiua-13635	72	6	genetic	genetic	ADJ
aiua-13635	72	7	testing	testing	NOUN
aiua-13635	72	8	using	use	VERB
aiua-13635	72	9	ffpe	ffpe	ADJ
aiua-13635	72	10	tissue	tissue	NOUN
aiua-13635	72	11	in	in	ADP
aiua-13635	72	12	the	the	DET
aiua-13635	72	13	clinical	clinical	ADJ
aiua-13635	72	14	setting	setting	NOUN
aiua-13635	72	15	of	of	ADP
aiua-13635	72	16	patients	patient	NOUN
aiua-13635	72	17	with	with	ADP
aiua-13635	72	18	high	high	ADJ
aiua-13635	72	19	-	-	PUNCT
aiua-13635	72	20	grade	grade	NOUN
aiua-13635	72	21	and/or	and/or	CCONJ
aiua-13635	72	22	metastatic	metastatic	ADJ
aiua-13635	72	23	pc	pc	NOUN
aiua-13635	72	24	appears	appear	VERB
aiua-13635	72	25	to	to	PART
aiua-13635	72	26	be	be	AUX
aiua-13635	72	27	a	a	DET
aiua-13635	72	28	valuable	valuable	ADJ
aiua-13635	72	29	tool	tool	NOUN
aiua-13635	72	30	,	,	PUNCT
aiua-13635	72	31	not	not	PART
aiua-13635	72	32	only	only	ADV
aiua-13635	72	33	for	for	ADP
aiua-13635	72	34	therapeutic	therapeutic	ADJ
aiua-13635	72	35	purposes	purpose	NOUN
aiua-13635	72	36	,	,	PUNCT
aiua-13635	72	37	but	but	CCONJ
aiua-13635	72	38	also	also	ADV
aiua-13635	72	39	to	to	PART
aiua-13635	72	40	identify	identify	VERB
aiua-13635	72	41	families	family	NOUN
aiua-13635	72	42	with	with	ADP
aiua-13635	72	43	genetic	genetic	ADJ
aiua-13635	72	44	predisposition	predisposition	NOUN
aiua-13635	72	45	who	who	PRON
aiua-13635	72	46	may	may	AUX
aiua-13635	72	47	be	be	AUX
aiua-13635	72	48	underdiagnosed	underdiagnose	VERB
aiua-13635	72	49	according	accord	VERB
aiua-13635	72	50	to	to	ADP
aiua-13635	72	51	canonical	canonical	ADJ
aiua-13635	72	52	criteria	criterion	NOUN
aiua-13635	72	53	.	.	PUNCT
aiua-13635	73	1	references	reference	NOUN
aiua-13635	73	2	1	1	NUM
aiua-13635	73	3	.	.	PUNCT
aiua-13635	73	4	kote	kote	VERB
aiua-13635	73	5	-	-	PUNCT
aiua-13635	73	6	jarai	jarai	PROPN
aiua-13635	73	7	z	z	NOUN
aiua-13635	73	8	,	,	PUNCT
aiua-13635	73	9	leongamornlert	leongamornlert	ADJ
aiua-13635	73	10	d	d	PROPN
aiua-13635	73	11	,	,	PUNCT
aiua-13635	73	12	saunders	saunders	PROPN
aiua-13635	73	13	e	e	PROPN
aiua-13635	73	14	,	,	PUNCT
aiua-13635	73	15	et	et	PROPN
aiua-13635	73	16	al	al	PROPN
aiua-13635	73	17	.	.	PUNCT
aiua-13635	74	1	brca2	brca2	PROPN
aiua-13635	74	2	is	be	AUX
aiua-13635	74	3	a	a	DET
aiua-13635	74	4	moderate	moderate	ADJ
aiua-13635	74	5	penetrance	penetrance	NOUN
aiua-13635	74	6	gene	gene	NOUN
aiua-13635	74	7	contributing	contribute	VERB
aiua-13635	74	8	to	to	ADP
aiua-13635	74	9	young	young	ADJ
aiua-13635	74	10	-	-	PUNCT
aiua-13635	74	11	onset	onset	VERB
aiua-13635	74	12	prostate	prostate	NOUN
aiua-13635	74	13	cancer	cancer	NOUN
aiua-13635	74	14	:	:	PUNCT
aiua-13635	74	15	implications	implication	NOUN
aiua-13635	74	16	for	for	ADP
aiua-13635	74	17	genetic	genetic	ADJ
aiua-13635	74	18	testing	testing	NOUN
aiua-13635	74	19	in	in	ADP
aiua-13635	74	20	prostate	prostate	NOUN
aiua-13635	74	21	cancer	cancer	NOUN
aiua-13635	74	22	patients	patient	NOUN
aiua-13635	74	23	.	.	PUNCT
aiua-13635	75	1	br	br	PROPN
aiua-13635	75	2	j	j	PROPN
aiua-13635	75	3	cancer	cancer	NOUN
aiua-13635	75	4	.	.	PUNCT
aiua-13635	76	1	2011	2011	NUM
aiua-13635	76	2	;	;	PUNCT
aiua-13635	76	3	105:1230	105:1230	NUM
aiua-13635	76	4	-	-	SYM
aiua-13635	76	5	1234	1234	NUM
aiua-13635	76	6	.	.	PUNCT
aiua-13635	77	1	2	2	X
aiua-13635	77	2	.	.	X
aiua-13635	77	3	sengodan	sengodan	PROPN
aiua-13635	77	4	sk	sk	PROPN
aiua-13635	77	5	,	,	PUNCT
aiua-13635	77	6	sreelatha	sreelatha	PROPN
aiua-13635	77	7	kh	kh	PROPN
aiua-13635	77	8	,	,	PUNCT
aiua-13635	77	9	nadhan	nadhan	INTJ
aiua-13635	77	10	r	r	PROPN
aiua-13635	77	11	,	,	PUNCT
aiua-13635	77	12	srinivas	srinivas	PROPN
aiua-13635	77	13	p.	p.	NOUN
aiua-13635	77	14	regulation	regulation	NOUN
aiua-13635	77	15	of	of	ADP
aiua-13635	77	16	epithelial	epithelial	ADJ
aiua-13635	77	17	to	to	ADP
aiua-13635	77	18	mesenchymal	mesenchymal	ADJ
aiua-13635	77	19	transition	transition	NOUN
aiua-13635	77	20	by	by	ADP
aiua-13635	77	21	brca1	brca1	PROPN
aiua-13635	77	22	in	in	ADP
aiua-13635	77	23	breast	breast	NOUN
aiua-13635	77	24	cancer	cancer	NOUN
aiua-13635	77	25	.	.	PUNCT
aiua-13635	78	1	crit	crit	PROPN
aiua-13635	78	2	rev	rev	PROPN
aiua-13635	78	3	oncol	oncol	ADJ
aiua-13635	78	4	/	/	SYM
aiua-13635	78	5	hematol	hematol	NOUN
aiua-13635	78	6	.	.	PUNCT
aiua-13635	79	1	2018	2018	NUM
aiua-13635	79	2	;	;	PUNCT
aiua-13635	80	1	123:74	123:74	NUM
aiua-13635	80	2	-	-	SYM
aiua-13635	80	3	82	82	NUM
aiua-13635	80	4	.	.	PUNCT
aiua-13635	81	1	3	3	X
aiua-13635	81	2	.	.	X
aiua-13635	81	3	bertwistle	bertwistle	PROPN
aiua-13635	81	4	d	d	PROPN
aiua-13635	81	5	,	,	PUNCT
aiua-13635	81	6	swift	swift	ADJ
aiua-13635	81	7	s	s	PROPN
aiua-13635	81	8	,	,	PUNCT
aiua-13635	81	9	marston	marston	PROPN
aiua-13635	81	10	nj	nj	PROPN
aiua-13635	81	11	,	,	PUNCT
aiua-13635	81	12	et	et	PROPN
aiua-13635	81	13	al	al	PROPN
aiua-13635	81	14	.	.	PUNCT
aiua-13635	81	15	nuclear	nuclear	ADJ
aiua-13635	81	16	location	location	NOUN
aiua-13635	81	17	and	and	CCONJ
aiua-13635	81	18	cell	cell	NOUN
aiua-13635	81	19	cycle	cycle	NOUN
aiua-13635	81	20	regulation	regulation	NOUN
aiua-13635	81	21	of	of	ADP
aiua-13635	81	22	the	the	DET
aiua-13635	81	23	brca2	brca2	NOUN
aiua-13635	81	24	protein1	protein1	PROPN
aiua-13635	81	25	.	.	PUNCT
aiua-13635	82	1	cancer	cancer	NOUN
aiua-13635	82	2	res	re	NOUN
aiua-13635	82	3	.	.	PUNCT
aiua-13635	82	4	1997	1997	NUM
aiua-13635	82	5	;	;	PUNCT
aiua-13635	82	6	57:5485	57:5485	NUM
aiua-13635	82	7	-	-	SYM
aiua-13635	82	8	5488	5488	NUM
aiua-13635	82	9	.	.	PUNCT
aiua-13635	83	1	4	4	X
aiua-13635	83	2	.	.	X
aiua-13635	83	3	castro	castro	PROPN
aiua-13635	83	4	e	e	PROPN
aiua-13635	83	5	,	,	PUNCT
aiua-13635	83	6	goh	goh	PROPN
aiua-13635	83	7	c	c	PROPN
aiua-13635	83	8	,	,	PUNCT
aiua-13635	83	9	olmos	olmos	PROPN
aiua-13635	83	10	d	d	PROPN
aiua-13635	83	11	,	,	PUNCT
aiua-13635	83	12	et	et	PROPN
aiua-13635	83	13	al	al	PROPN
aiua-13635	83	14	.	.	PROPN
aiua-13635	83	15	germline	germline	PROPN
aiua-13635	83	16	brca	brca	PROPN
aiua-13635	83	17	mutations	mutation	NOUN
aiua-13635	83	18	are	be	AUX
aiua-13635	83	19	associated	associate	VERB
aiua-13635	83	20	with	with	ADP
aiua-13635	83	21	higher	high	ADJ
aiua-13635	83	22	risk	risk	NOUN
aiua-13635	83	23	of	of	ADP
aiua-13635	83	24	nodal	nodal	NOUN
aiua-13635	83	25	involvement	involvement	NOUN
aiua-13635	83	26	,	,	PUNCT
aiua-13635	83	27	distant	distant	ADJ
aiua-13635	83	28	metastasis	metastasis	NOUN
aiua-13635	83	29	,	,	PUNCT
aiua-13635	83	30	and	and	CCONJ
aiua-13635	83	31	poor	poor	ADJ
aiua-13635	83	32	survival	survival	NOUN
aiua-13635	83	33	outcomes	outcome	NOUN
aiua-13635	83	34	in	in	ADP
aiua-13635	83	35	prostate	prostate	NOUN
aiua-13635	83	36	cancer	cancer	NOUN
aiua-13635	83	37	.	.	PUNCT
aiua-13635	84	1	j	j	PROPN
aiua-13635	84	2	clin	clin	PROPN
aiua-13635	84	3	oncol	oncol	PROPN
aiua-13635	84	4	.	.	PUNCT
aiua-13635	85	1	2013	2013	NUM
aiua-13635	85	2	;	;	PUNCT
aiua-13635	85	3	31:1748	31:1748	NOUN
aiua-13635	85	4	-	-	SYM
aiua-13635	85	5	1757	1757	NUM
aiua-13635	85	6	.	.	PUNCT
aiua-13635	86	1	5	5	X
aiua-13635	86	2	.	.	X
aiua-13635	86	3	taylor	taylor	PROPN
aiua-13635	86	4	ra	ra	PROPN
aiua-13635	86	5	,	,	PUNCT
aiua-13635	86	6	fraser	fraser	PROPN
aiua-13635	86	7	m	m	PROPN
aiua-13635	86	8	,	,	PUNCT
aiua-13635	86	9	livingstone	livingstone	PROPN
aiua-13635	86	10	j	j	PROPN
aiua-13635	86	11	,	,	PUNCT
aiua-13635	86	12	et	et	PROPN
aiua-13635	86	13	al	al	PROPN
aiua-13635	86	14	.	.	PROPN
aiua-13635	86	15	germline	germline	PROPN
aiua-13635	86	16	brca2	brca2	PROPN
aiua-13635	86	17	mutations	mutation	NOUN
aiua-13635	86	18	drive	drive	VERB
aiua-13635	86	19	prostate	prostate	NOUN
aiua-13635	86	20	cancers	cancer	NOUN
aiua-13635	86	21	with	with	ADP
aiua-13635	86	22	distinct	distinct	ADJ
aiua-13635	86	23	evolutionary	evolutionary	ADJ
aiua-13635	86	24	trajectories	trajectory	NOUN
aiua-13635	86	25	.	.	PUNCT
aiua-13635	87	1	nat	nat	PROPN
aiua-13635	87	2	commun	commun	PROPN
aiua-13635	87	3	.	.	PROPN
aiua-13635	87	4	2017	2017	NUM
aiua-13635	87	5	;	;	PUNCT
aiua-13635	87	6	8:13671	8:13671	NUM
aiua-13635	87	7	.	.	NOUN
aiua-13635	87	8	6	6	NUM
aiua-13635	87	9	.	.	X
aiua-13635	87	10	pepe	pepe	PROPN
aiua-13635	87	11	p	p	PROPN
aiua-13635	87	12	,	,	PUNCT
aiua-13635	87	13	aragona	aragona	PROPN
aiua-13635	87	14	f.	f.	PROPN
aiua-13635	87	15	incidence	incidence	PROPN
aiua-13635	87	16	of	of	ADP
aiua-13635	87	17	insignificant	insignificant	ADJ
aiua-13635	87	18	prostate	prostate	NOUN
aiua-13635	87	19	cancer	cancer	NOUN
aiua-13635	87	20	using	use	VERB
aiua-13635	87	21	free	free	ADJ
aiua-13635	87	22	/	/	SYM
aiua-13635	87	23	total	total	ADJ
aiua-13635	87	24	psa	psa	NOUN
aiua-13635	87	25	:	:	PUNCT
aiua-13635	87	26	results	result	NOUN
aiua-13635	87	27	of	of	ADP
aiua-13635	87	28	a	a	DET
aiua-13635	87	29	case	case	NOUN
aiua-13635	87	30	-	-	PUNCT
aiua-13635	87	31	finding	find	VERB
aiua-13635	87	32	protocol	protocol	NOUN
aiua-13635	87	33	on	on	ADP
aiua-13635	87	34	14,453	14,453	NUM
aiua-13635	87	35	patients	patient	NOUN
aiua-13635	87	36	.	.	PUNCT
aiua-13635	88	1	prostate	prostate	NOUN
aiua-13635	88	2	cancer	cancer	NOUN
aiua-13635	88	3	prostatic	prostatic	ADJ
aiua-13635	88	4	dis	dis	PROPN
aiua-13635	88	5	.	.	PUNCT
aiua-13635	89	1	2010	2010	NUM
aiua-13635	89	2	;	;	PUNCT
aiua-13635	89	3	13:316	13:316	NUM
aiua-13635	89	4	-	-	SYM
aiua-13635	89	5	319	319	NUM
aiua-13635	89	6	.	.	PUNCT
aiua-13635	90	1	7	7	X
aiua-13635	90	2	.	.	X
aiua-13635	90	3	pepe	pepe	PROPN
aiua-13635	90	4	p	p	NOUN
aiua-13635	90	5	,	,	PUNCT
aiua-13635	90	6	panella	panella	NOUN
aiua-13635	90	7	p	p	NOUN
aiua-13635	90	8	,	,	PUNCT
aiua-13635	90	9	d'arrigo	d'arrigo	PROPN
aiua-13635	90	10	l	l	NOUN
aiua-13635	90	11	,	,	PUNCT
aiua-13635	90	12	et	et	PROPN
aiua-13635	90	13	al	al	PROPN
aiua-13635	90	14	.	.	PUNCT
aiua-13635	91	1	should	should	AUX
aiua-13635	91	2	men	man	NOUN
aiua-13635	91	3	with	with	ADP
aiua-13635	91	4	serum	serum	NOUN
aiua-13635	91	5	prostate	prostate	NOUN
aiua-13635	91	6	-	-	PUNCT
aiua-13635	91	7	specific	specific	ADJ
aiua-13635	91	8	antigen	antigen	NOUN
aiua-13635	91	9	<	<	X
aiua-13635	91	10	or	or	CCONJ
aiua-13635	91	11	=	=	SYM
aiua-13635	91	12	4	4	NUM
aiua-13635	91	13	ng	ng	NOUN
aiua-13635	91	14	/	/	SYM
aiua-13635	91	15	ml	ml	NOUN
aiua-13635	91	16	and	and	CCONJ
aiua-13635	91	17	normal	normal	ADJ
aiua-13635	91	18	digital	digital	ADJ
aiua-13635	91	19	rectal	rectal	ADJ
aiua-13635	91	20	examination	examination	NOUN
aiua-13635	91	21	undergo	undergo	VERB
aiua-13635	91	22	a	a	DET
aiua-13635	91	23	prostate	prostate	NOUN
aiua-13635	91	24	biopsy	biopsy	NOUN
aiua-13635	91	25	?	?	PUNCT
aiua-13635	92	1	a	a	DET
aiua-13635	92	2	literature	literature	NOUN
aiua-13635	92	3	review	review	NOUN
aiua-13635	92	4	.	.	PUNCT
aiua-13635	93	1	oncology	oncology	NOUN
aiua-13635	93	2	.	.	PUNCT
aiua-13635	94	1	2006	2006	NUM
aiua-13635	94	2	;	;	PUNCT
aiua-13635	94	3	70:81	70:81	NUM
aiua-13635	94	4	-	-	SYM
aiua-13635	94	5	98	98	NUM
aiua-13635	94	6	.	.	NOUN
aiua-13635	95	1	8	8	NUM
aiua-13635	95	2	.	.	X
aiua-13635	95	3	aragona	aragona	PROPN
aiua-13635	96	1	f	f	PROPN
aiua-13635	96	2	,	,	PUNCT
aiua-13635	96	3	pepe	pepe	PROPN
aiua-13635	96	4	p	p	PROPN
aiua-13635	96	5	,	,	PUNCT
aiua-13635	96	6	motta	motta	PROPN
aiua-13635	96	7	m	m	PROPN
aiua-13635	96	8	,	,	PUNCT
aiua-13635	96	9	et	et	PROPN
aiua-13635	96	10	al	al	PROPN
aiua-13635	96	11	.	.	PROPN
aiua-13635	96	12	incidence	incidence	NOUN
aiua-13635	96	13	of	of	ADP
aiua-13635	96	14	prostate	prostate	NOUN
aiua-13635	96	15	cancer	cancer	NOUN
aiua-13635	96	16	in	in	ADP
aiua-13635	96	17	sicily	sicily	ADV
aiua-13635	96	18	:	:	PUNCT
aiua-13635	96	19	results	result	NOUN
aiua-13635	96	20	of	of	ADP
aiua-13635	96	21	a	a	DET
aiua-13635	96	22	multicenter	multicenter	ADJ
aiua-13635	96	23	case	case	NOUN
aiua-13635	96	24	-	-	PUNCT
aiua-13635	96	25	findings	finding	NOUN
aiua-13635	96	26	protocol	protocol	NOUN
aiua-13635	96	27	.	.	PUNCT
aiua-13635	97	1	eur	eur	PROPN
aiua-13635	97	2	urol	urol	PROPN
aiua-13635	97	3	.	.	PUNCT
aiua-13635	98	1	2005	2005	NUM
aiua-13635	98	2	;	;	PUNCT
aiua-13635	98	3	47:569	47:569	NUM
aiua-13635	98	4	-	-	SYM
aiua-13635	98	5	74	74	NUM
aiua-13635	98	6	.	.	NOUN
aiua-13635	99	1	9	9	NUM
aiua-13635	99	2	.	.	X
aiua-13635	99	3	pepe	pepe	PROPN
aiua-13635	99	4	p	p	PROPN
aiua-13635	99	5	,	,	PUNCT
aiua-13635	99	6	aragona	aragona	PROPN
aiua-13635	99	7	f.	f.	PROPN
aiua-13635	99	8	prostate	prostate	PROPN
aiua-13635	99	9	cancer	cancer	NOUN
aiua-13635	99	10	detection	detection	NOUN
aiua-13635	99	11	rate	rate	NOUN
aiua-13635	99	12	at	at	ADP
aiua-13635	99	13	repeat	repeat	NOUN
aiua-13635	99	14	saturation	saturation	NOUN
aiua-13635	99	15	biopsy	biopsy	NOUN
aiua-13635	99	16	:	:	PUNCT
aiua-13635	99	17	pcpt	pcpt	NOUN
aiua-13635	99	18	risk	risk	NOUN
aiua-13635	99	19	calculator	calculator	NOUN
aiua-13635	99	20	versus	versus	ADP
aiua-13635	99	21	pca3	pca3	PROPN
aiua-13635	99	22	score	score	NOUN
aiua-13635	99	23	versus	versus	ADP
aiua-13635	99	24	casefinding	casefinde	VERB
aiua-13635	99	25	protocol	protocol	NOUN
aiua-13635	99	26	.	.	PUNCT
aiua-13635	100	1	can	can	AUX
aiua-13635	100	2	j	j	PROPN
aiua-13635	100	3	urol	urol	PROPN
aiua-13635	100	4	.	.	PUNCT
aiua-13635	101	1	2013	2013	NUM
aiua-13635	101	2	;	;	PUNCT
aiua-13635	101	3	20:6620	20:6620	NUM
aiua-13635	101	4	-	-	SYM
aiua-13635	101	5	6624	6624	NUM
aiua-13635	101	6	.	.	PUNCT
aiua-13635	102	1	10	10	NUM
aiua-13635	102	2	.	.	PUNCT
aiua-13635	102	3	pepe	pepe	PROPN
aiua-13635	102	4	p	p	PROPN
aiua-13635	102	5	,	,	PUNCT
aiua-13635	102	6	d'urso	d'urso	PROPN
aiua-13635	102	7	d	d	NOUN
aiua-13635	102	8	,	,	PUNCT
aiua-13635	102	9	garufi	garufi	PROPN
aiua-13635	102	10	a	a	X
aiua-13635	102	11	,	,	PUNCT
aiua-13635	102	12	et	et	PROPN
aiua-13635	102	13	al	al	PROPN
aiua-13635	102	14	.	.	PROPN
aiua-13635	102	15	multiparametric	multiparametric	PROPN
aiua-13635	102	16	mri	mri	PROPN
aiua-13635	102	17	apparent	apparent	ADJ
aiua-13635	102	18	diffusion	diffusion	NOUN
aiua-13635	102	19	coefficient	coefficient	NOUN
aiua-13635	102	20	(	(	PUNCT
aiua-13635	102	21	adc	adc	PROPN
aiua-13635	102	22	)	)	PUNCT
aiua-13635	102	23	accuracy	accuracy	NOUN
aiua-13635	102	24	in	in	ADP
aiua-13635	102	25	diagnosing	diagnose	VERB
aiua-13635	102	26	clinically	clinically	ADV
aiua-13635	102	27	significant	significant	ADJ
aiua-13635	102	28	prostate	prostate	NOUN
aiua-13635	102	29	cancer	cancer	NOUN
aiua-13635	102	30	.	.	PUNCT
aiua-13635	103	1	in	in	ADP
aiua-13635	103	2	vivo	vivo	NOUN
aiua-13635	103	3	.	.	PUNCT
aiua-13635	104	1	2017	2017	NUM
aiua-13635	104	2	;	;	PUNCT
aiua-13635	104	3	31:415	31:415	NUM
aiua-13635	104	4	-	-	SYM
aiua-13635	104	5	418	418	NUM
aiua-13635	104	6	.	.	PUNCT
aiua-13635	105	1	11	11	NUM
aiua-13635	105	2	.	.	PUNCT
aiua-13635	106	1	pepe	pepe	PROPN
aiua-13635	106	2	p	p	PROPN
aiua-13635	106	3	,	,	PUNCT
aiua-13635	106	4	fraggetta	fraggetta	PROPN
aiua-13635	106	5	f	f	PROPN
aiua-13635	106	6	,	,	PUNCT
aiua-13635	106	7	galia	galia	PROPN
aiua-13635	106	8	a	a	PROPN
aiua-13635	106	9	,	,	PUNCT
aiua-13635	106	10	et	et	PROPN
aiua-13635	106	11	al	al	PROPN
aiua-13635	106	12	.	.	PUNCT
aiua-13635	106	13	pca3	pca3	PROPN
aiua-13635	106	14	score	score	NOUN
aiua-13635	106	15	and	and	CCONJ
aiua-13635	106	16	prostate	prostate	NOUN
aiua-13635	106	17	cancer	cancer	NOUN
aiua-13635	106	18	diagnosis	diagnosis	NOUN
aiua-13635	106	19	at	at	ADP
aiua-13635	106	20	repeated	repeat	VERB
aiua-13635	106	21	saturation	saturation	NOUN
aiua-13635	106	22	biopsy	biopsy	NOUN
aiua-13635	106	23	.	.	PUNCT
aiua-13635	107	1	which	which	PRON
aiua-13635	107	2	cut	cut	NOUN
aiua-13635	107	3	-	-	PUNCT
aiua-13635	107	4	off	off	ADP
aiua-13635	107	5	:	:	PUNCT
aiua-13635	107	6	20	20	NUM
aiua-13635	107	7	or	or	CCONJ
aiua-13635	107	8	35	35	NUM
aiua-13635	107	9	?	?	PUNCT
aiua-13635	107	10	int	int	PROPN
aiua-13635	107	11	braz	braz	PROPN
aiua-13635	107	12	j	j	PROPN
aiua-13635	107	13	urol	urol	PROPN
aiua-13635	107	14	.	.	PUNCT
aiua-13635	107	15	2012	2012	NUM
aiua-13635	107	16	;	;	PUNCT
aiua-13635	107	17	38:489	38:489	NUM
aiua-13635	107	18	-	-	SYM
aiua-13635	107	19	495	495	NUM
aiua-13635	107	20	.	.	PUNCT
aiua-13635	108	1	12	12	NUM
aiua-13635	108	2	.	.	PUNCT
aiua-13635	109	1	pepe	pepe	PROPN
aiua-13635	109	2	p	p	PROPN
aiua-13635	109	3	,	,	PUNCT
aiua-13635	109	4	aragona	aragona	PROPN
aiua-13635	109	5	f.	f.	PROPN
aiua-13635	109	6	pca3	pca3	PROPN
aiua-13635	109	7	score	score	VERB
aiua-13635	109	8	vs	vs	ADP
aiua-13635	109	9	psa	psa	NOUN
aiua-13635	109	10	free	free	ADJ
aiua-13635	109	11	/	/	SYM
aiua-13635	109	12	total	total	ADJ
aiua-13635	109	13	accuracy	accuracy	NOUN
aiua-13635	109	14	in	in	ADP
aiua-13635	109	15	prostate	prostate	NOUN
aiua-13635	109	16	cancer	cancer	NOUN
aiua-13635	109	17	diagnosis	diagnosis	NOUN
aiua-13635	109	18	at	at	ADP
aiua-13635	109	19	repeat	repeat	NOUN
aiua-13635	109	20	saturation	saturation	NOUN
aiua-13635	109	21	biopsy	biopsy	NOUN
aiua-13635	109	22	.	.	PUNCT
aiua-13635	110	1	anticancer	anticancer	NOUN
aiua-13635	110	2	res	re	NOUN
aiua-13635	110	3	.	.	PUNCT
aiua-13635	110	4	2011	2011	NUM
aiua-13635	110	5	;	;	PUNCT
aiua-13635	110	6	31:4445	31:4445	PROPN
aiua-13635	110	7	-	-	SYM
aiua-13635	110	8	4449	4449	NUM
aiua-13635	110	9	.	.	PUNCT
aiua-13635	111	1	13	13	NUM
aiua-13635	111	2	.	.	PUNCT
aiua-13635	111	3	page	page	NOUN
aiua-13635	111	4	ec	ec	PROPN
aiua-13635	111	5	,	,	PUNCT
aiua-13635	111	6	bancroft	bancroft	PROPN
aiua-13635	111	7	ek	ek	PROPN
aiua-13635	111	8	,	,	PUNCT
aiua-13635	111	9	brook	brook	PROPN
aiua-13635	111	10	mn	mn	PROPN
aiua-13635	111	11	,	,	PUNCT
aiua-13635	111	12	et	et	PROPN
aiua-13635	111	13	al	al	PROPN
aiua-13635	111	14	.	.	PROPN
aiua-13635	111	15	interim	interim	ADJ
aiua-13635	111	16	results	result	NOUN
aiua-13635	111	17	from	from	ADP
aiua-13635	111	18	the	the	DET
aiua-13635	111	19	impact	impact	NOUN
aiua-13635	111	20	study	study	NOUN
aiua-13635	111	21	:	:	PUNCT
aiua-13635	111	22	evidence	evidence	NOUN
aiua-13635	111	23	for	for	ADP
aiua-13635	111	24	prostate	prostate	NOUN
aiua-13635	111	25	-	-	PUNCT
aiua-13635	111	26	specific	specific	ADJ
aiua-13635	111	27	antigen	antigen	NOUN
aiua-13635	111	28	screening	screening	NOUN
aiua-13635	111	29	in	in	ADP
aiua-13635	111	30	brca2	brca2	NOUN
aiua-13635	111	31	mutation	mutation	NOUN
aiua-13635	111	32	carriers	carrier	NOUN
aiua-13635	111	33	.	.	PUNCT
aiua-13635	112	1	eur	eur	PROPN
aiua-13635	112	2	urol	urol	PROPN
aiua-13635	112	3	.	.	PROPN
aiua-13635	113	1	2019	2019	NUM
aiua-13635	113	2	;	;	PUNCT
aiua-13635	113	3	76:831	76:831	NUM
aiua-13635	113	4	-	-	SYM
aiua-13635	113	5	842	842	NUM
aiua-13635	113	6	.	.	PUNCT
aiua-13635	114	1	14	14	NUM
aiua-13635	114	2	.	.	PUNCT
aiua-13635	115	1	pepe	pepe	PROPN
aiua-13635	115	2	p	p	PROPN
aiua-13635	115	3	,	,	PUNCT
aiua-13635	115	4	dibenedetto	dibenedetto	PROPN
aiua-13635	115	5	g	g	NOUN
aiua-13635	115	6	,	,	PUNCT
aiua-13635	115	7	pennisi	pennisi	VERB
aiua-13635	115	8	m	m	PROPN
aiua-13635	115	9	,	,	PUNCT
aiua-13635	115	10	et	et	PROPN
aiua-13635	115	11	al	al	PROPN
aiua-13635	115	12	.	.	PUNCT
aiua-13635	115	13	detection	detection	NOUN
aiua-13635	115	14	rate	rate	NOUN
aiua-13635	115	15	of	of	ADP
aiua-13635	115	16	anterior	anterior	ADJ
aiua-13635	115	17	prostate	prostate	NOUN
aiua-13635	115	18	cancer	cancer	NOUN
aiua-13635	115	19	in	in	ADP
aiua-13635	115	20	226	226	NUM
aiua-13635	115	21	patients	patient	NOUN
aiua-13635	115	22	submitted	submit	VERB
aiua-13635	115	23	to	to	ADP
aiua-13635	115	24	initial	initial	ADJ
aiua-13635	115	25	and	and	CCONJ
aiua-13635	115	26	repeat	repeat	NOUN
aiua-13635	115	27	transperineal	transperineal	NOUN
aiua-13635	115	28	biopsy	biopsy	NOUN
aiua-13635	115	29	.	.	PUNCT
aiua-13635	116	1	urol	urol	PROPN
aiua-13635	116	2	int	int	PROPN
aiua-13635	116	3	.	.	PUNCT
aiua-13635	117	1	2014	2014	NUM
aiua-13635	117	2	;	;	PUNCT
aiua-13635	117	3	93:189	93:189	NUM
aiua-13635	117	4	-	-	PUNCT
aiua-13635	117	5	192	192	NUM
aiua-13635	117	6	.	.	NOUN
aiua-13635	118	1	15	15	NUM
aiua-13635	118	2	.	.	PUNCT
aiua-13635	119	1	pepe	pepe	PROPN
aiua-13635	119	2	p	p	PROPN
aiua-13635	119	3	,	,	PUNCT
aiua-13635	119	4	pepe	pepe	PROPN
aiua-13635	119	5	l	l	PROPN
aiua-13635	119	6	,	,	PUNCT
aiua-13635	119	7	tamburo	tamburo	NOUN
aiua-13635	119	8	m	m	PROPN
aiua-13635	119	9	,	,	PUNCT
aiua-13635	119	10	et	et	PROPN
aiua-13635	119	11	al	al	PROPN
aiua-13635	119	12	.	.	PUNCT
aiua-13635	120	1	68ga	68ga	ADJ
aiua-13635	120	2	-	-	PUNCT
aiua-13635	120	3	psma	psma	NOUN
aiua-13635	120	4	pet	pet	NOUN
aiua-13635	120	5	/	/	SYM
aiua-13635	120	6	ct	ct	PROPN
aiua-13635	120	7	and	and	CCONJ
aiua-13635	120	8	prostate	prostate	NOUN
aiua-13635	120	9	cancer	cancer	NOUN
aiua-13635	120	10	diagnosis	diagnosis	NOUN
aiua-13635	120	11	:	:	PUNCT
aiua-13635	120	12	which	which	DET
aiua-13635	120	13	suvmax	suvmax	ADJ
aiua-13635	120	14	value	value	NOUN
aiua-13635	120	15	?	?	PUNCT
aiua-13635	121	1	in	in	ADP
aiua-13635	121	2	vivo	vivo	NOUN
aiua-13635	121	3	.	.	PUNCT
aiua-13635	122	1	2023	2023	NUM
aiua-13635	122	2	;	;	PUNCT
aiua-13635	122	3	37:1318	37:1318	X
aiua-13635	122	4	-	-	SYM
aiua-13635	122	5	1322	1322	NUM
aiua-13635	122	6	.	.	PUNCT
aiua-13635	123	1	16	16	NUM
aiua-13635	123	2	.	.	PUNCT
aiua-13635	124	1	pepe	pepe	PROPN
aiua-13635	124	2	p	p	PROPN
aiua-13635	124	3	,	,	PUNCT
aiua-13635	124	4	pennisi	pennisi	VERB
aiua-13635	124	5	m.	m.	NOUN
aiua-13635	124	6	targeted	target	VERB
aiua-13635	124	7	biopsy	biopsy	NOUN
aiua-13635	124	8	in	in	ADP
aiua-13635	124	9	men	man	NOUN
aiua-13635	124	10	high	high	ADJ
aiua-13635	124	11	risk	risk	NOUN
aiua-13635	124	12	for	for	ADP
aiua-13635	124	13	prostate	prostate	NOUN
aiua-13635	124	14	cancer	cancer	NOUN
aiua-13635	124	15	:	:	PUNCT
aiua-13635	124	16	68ga	68ga	ADJ
aiua-13635	124	17	-	-	PUNCT
aiua-13635	124	18	psma	psma	NOUN
aiua-13635	124	19	pet	pet	NOUN
aiua-13635	124	20	/	/	SYM
aiua-13635	124	21	ct	ct	PROPN
aiua-13635	124	22	versus	versus	ADP
aiua-13635	124	23	mpmri	mpmri	PROPN
aiua-13635	124	24	.	.	PUNCT
aiua-13635	125	1	clin	clin	PROPN
aiua-13635	125	2	genitourin	genitourin	PROPN
aiua-13635	125	3	cancer	cancer	NOUN
aiua-13635	125	4	.	.	PUNCT
aiua-13635	126	1	2023	2023	NUM
aiua-13635	126	2	;	;	PUNCT
aiua-13635	126	3	21:639	21:639	NUM
aiua-13635	126	4	-	-	SYM
aiua-13635	126	5	642	642	NUM
aiua-13635	126	6	.	.	PUNCT
aiua-13635	127	1	17	17	NUM
aiua-13635	127	2	.	.	X
aiua-13635	127	3	salemi	salemi	PROPN
aiua-13635	127	4	m	m	PROPN
aiua-13635	127	5	,	,	PUNCT
aiua-13635	127	6	pettinato	pettinato	NOUN
aiua-13635	127	7	a	a	PRON
aiua-13635	127	8	,	,	PUNCT
aiua-13635	127	9	fraggetta	fraggetta	ADJ
aiua-13635	127	10	f	f	NOUN
aiua-13635	127	11	,	,	PUNCT
aiua-13635	127	12	et	et	PROPN
aiua-13635	127	13	al	al	PROPN
aiua-13635	127	14	.	.	PUNCT
aiua-13635	128	1	expression	expression	NOUN
aiua-13635	128	2	of	of	ADP
aiua-13635	128	3	mir-132	mir-132	PRON
aiua-13635	128	4	and	and	CCONJ
aiua-13635	128	5	mir-212	mir-212	VERB
aiua-13635	128	6	in	in	ADP
aiua-13635	128	7	prostate	prostate	NOUN
aiua-13635	128	8	cancer	cancer	NOUN
aiua-13635	128	9	and	and	CCONJ
aiua-13635	128	10	metastatic	metastatic	ADJ
aiua-13635	128	11	lymph	lymph	NOUN
aiua-13635	128	12	node	node	NOUN
aiua-13635	128	13	:	:	PUNCT
aiua-13635	128	14	case	case	NOUN
aiua-13635	128	15	report	report	NOUN
aiua-13635	128	16	and	and	CCONJ
aiua-13635	128	17	revision	revision	NOUN
aiua-13635	128	18	of	of	ADP
aiua-13635	128	19	the	the	DET
aiua-13635	128	20	literature	literature	NOUN
aiua-13635	128	21	.	.	PUNCT
aiua-13635	129	1	arch	arch	PROPN
aiua-13635	129	2	ital	ital	PROPN
aiua-13635	129	3	urol	urol	PROPN
aiua-13635	129	4	androl	androl	PROPN
aiua-13635	129	5	.	.	PUNCT
aiua-13635	129	6	2020	2020	NUM
aiua-13635	129	7	;	;	PUNCT
aiua-13635	129	8	92:209	92:209	NUM
aiua-13635	129	9	.	.	PUNCT
aiua-13635	130	1	18	18	NUM
aiua-13635	130	2	.	.	PUNCT
aiua-13635	130	3	pepe	pepe	PROPN
aiua-13635	130	4	p	p	PROPN
aiua-13635	130	5	,	,	PUNCT
aiua-13635	130	6	pepe	pepe	PROPN
aiua-13635	130	7	l	l	PROPN
aiua-13635	130	8	,	,	PUNCT
aiua-13635	130	9	cosentino	cosentino	PROPN
aiua-13635	130	10	s	s	PROPN
aiua-13635	130	11	,	,	PUNCT
aiua-13635	130	12	et	et	PROPN
aiua-13635	130	13	al	al	PROPN
aiua-13635	130	14	.	.	PUNCT
aiua-13635	130	15	detection	detection	NOUN
aiua-13635	130	16	rate	rate	NOUN
aiua-13635	130	17	of	of	ADP
aiua-13635	130	18	68ga	68ga	ADJ
aiua-13635	130	19	-	-	PUNCT
aiua-13635	130	20	psma	psma	NOUN
aiua-13635	130	21	pet	pet	NOUN
aiua-13635	130	22	/	/	SYM
aiua-13635	130	23	ct	ct	PROPN
aiua-13635	130	24	vs.	vs.	X
aiua-13635	130	25	mpmri	mpmri	PROPN
aiua-13635	130	26	targeted	target	VERB
aiua-13635	130	27	biopsy	biopsy	NOUN
aiua-13635	130	28	for	for	ADP
aiua-13635	130	29	clinically	clinically	ADV
aiua-13635	130	30	significant	significant	ADJ
aiua-13635	130	31	prostate	prostate	NOUN
aiua-13635	130	32	cancer	cancer	NOUN
aiua-13635	130	33	.	.	PUNCT
aiua-13635	131	1	anticancer	anticancer	NOUN
aiua-13635	131	2	res	re	NOUN
aiua-13635	131	3	.	.	PUNCT
aiua-13635	131	4	2022	2022	NUM
aiua-13635	131	5	;	;	PUNCT
aiua-13635	131	6	42:3011	42:3011	X
aiua-13635	131	7	-	-	SYM
aiua-13635	131	8	3015	3015	NUM
aiua-13635	131	9	.	.	PUNCT
aiua-13635	132	1	19	19	NUM
aiua-13635	132	2	.	.	PUNCT
aiua-13635	132	3	pepe	pepe	PROPN
aiua-13635	132	4	p	p	PROPN
aiua-13635	132	5	,	,	PUNCT
aiua-13635	132	6	pepe	pepe	PROPN
aiua-13635	132	7	l	l	PROPN
aiua-13635	132	8	,	,	PUNCT
aiua-13635	132	9	tamburo	tamburo	NOUN
aiua-13635	132	10	m	m	PROPN
aiua-13635	132	11	,	,	PUNCT
aiua-13635	132	12	et	et	PROPN
aiua-13635	132	13	al	al	PROPN
aiua-13635	132	14	.	.	PROPN
aiua-13635	132	15	targeted	target	VERB
aiua-13635	132	16	prostate	prostate	NOUN
aiua-13635	132	17	biopsy	biopsy	NOUN
aiua-13635	132	18	:	:	PUNCT
aiua-13635	132	19	declarations	declaration	NOUN
aiua-13635	132	20	ethical	ethical	ADJ
aiua-13635	132	21	approval	approval	NOUN
aiua-13635	132	22	:	:	PUNCT
aiua-13635	132	23	institutional	institutional	ADJ
aiua-13635	132	24	review	review	NOUN
aiua-13635	132	25	board	board	PROPN
aiua-13635	132	26	and	and	CCONJ
aiua-13635	132	27	ethical	ethical	ADJ
aiua-13635	132	28	committee	committee	NOUN
aiua-13635	132	29	approval	approval	NOUN
aiua-13635	132	30	were	be	AUX
aiua-13635	132	31	granted	grant	VERB
aiua-13635	132	32	the	the	DET
aiua-13635	132	33	informed	informed	ADJ
aiua-13635	132	34	consent	consent	NOUN
aiua-13635	132	35	was	be	AUX
aiua-13635	132	36	obtained	obtain	VERB
aiua-13635	132	37	from	from	ADP
aiua-13635	132	38	all	all	DET
aiua-13635	132	39	individual	individual	ADJ
aiua-13635	132	40	partecipants	partecipant	NOUN
aiua-13635	132	41	included	include	VERB
aiua-13635	132	42	in	in	ADP
aiua-13635	132	43	the	the	DET
aiua-13635	132	44	study	study	NOUN
aiua-13635	132	45	.	.	PUNCT
aiua-13635	133	1	availability	availability	NOUN
aiua-13635	133	2	of	of	ADP
aiua-13635	133	3	data	datum	NOUN
aiua-13635	133	4	and	and	CCONJ
aiua-13635	133	5	material	material	NOUN
aiua-13635	133	6	:	:	PUNCT
aiua-13635	133	7	the	the	DET
aiua-13635	133	8	data	datum	NOUN
aiua-13635	133	9	that	that	PRON
aiua-13635	133	10	support	support	VERB
aiua-13635	133	11	the	the	DET
aiua-13635	133	12	findings	finding	NOUN
aiua-13635	133	13	of	of	ADP
aiua-13635	133	14	this	this	DET
aiua-13635	133	15	study	study	NOUN
aiua-13635	133	16	are	be	AUX
aiua-13635	133	17	available	available	ADJ
aiua-13635	133	18	from	from	ADP
aiua-13635	133	19	the	the	DET
aiua-13635	133	20	corresponding	correspond	VERB
aiua-13635	133	21	authors	author	NOUN
aiua-13635	133	22	upon	upon	SCONJ
aiua-13635	133	23	reasonable	reasonable	ADJ
aiua-13635	133	24	request	request	NOUN
aiua-13635	133	25	.	.	PUNCT
aiua-13635	134	1	competing	compete	VERB
aiua-13635	134	2	interests	interest	NOUN
aiua-13635	134	3	:	:	PUNCT
aiua-13635	134	4	the	the	DET
aiua-13635	134	5	authors	author	NOUN
aiua-13635	134	6	declare	declare	VERB
aiua-13635	134	7	that	that	SCONJ
aiua-13635	134	8	there	there	PRON
aiua-13635	134	9	is	be	VERB
aiua-13635	134	10	no	no	DET
aiua-13635	134	11	conflict	conflict	NOUN
aiua-13635	134	12	of	of	ADP
aiua-13635	134	13	interest	interest	NOUN
aiua-13635	134	14	.	.	PUNCT
aiua-13635	135	1	funding	funding	NOUN
aiua-13635	135	2	:	:	PUNCT
aiua-13635	135	3	none	none	NOUN
aiua-13635	135	4	.	.	PUNCT
aiua-13635	136	1	authors	author	NOUN
aiua-13635	136	2	'	'	PART
aiua-13635	136	3	contributions	contribution	NOUN
aiua-13635	136	4	:	:	PUNCT
aiua-13635	136	5	conceptualization	conceptualization	NOUN
aiua-13635	136	6	:	:	PUNCT
aiua-13635	136	7	v.s.	v.s.	ADJ
aiua-13635	136	8	,	,	PUNCT
aiua-13635	136	9	p.p	p.p	PROPN
aiua-13635	136	10	.	.	PROPN
aiua-13635	136	11	,	,	PUNCT
aiua-13635	136	12	p.l	p.l	PROPN
aiua-13635	136	13	.	.	PROPN
aiua-13635	136	14	;	;	PUNCT
aiua-13635	136	15	investigation	investigation	NOUN
aiua-13635	136	16	:	:	PUNCT
aiua-13635	137	1	v.s.	v.s.	X
aiua-13635	137	2	,	,	PUNCT
aiua-13635	137	3	p.p	p.p	PROPN
aiua-13635	137	4	.	.	PROPN
aiua-13635	137	5	,	,	PUNCT
aiua-13635	137	6	p.l	p.l	PROPN
aiua-13635	137	7	.	.	PROPN
aiua-13635	137	8	;	;	PUNCT
aiua-13635	137	9	data	datum	NOUN
aiua-13635	137	10	curation	curation	NOUN
aiua-13635	137	11	:	:	PUNCT
aiua-13635	137	12	v.s.	v.s.	ADJ
aiua-13635	137	13	,	,	PUNCT
aiua-13635	137	14	p.p	p.p	PROPN
aiua-13635	137	15	.	.	PROPN
aiua-13635	137	16	,	,	PUNCT
aiua-13635	137	17	p.l	p.l	PROPN
aiua-13635	137	18	.	.	PROPN
aiua-13635	137	19	;	;	PUNCT
aiua-13635	137	20	formal	formal	ADJ
aiua-13635	137	21	analysis	analysis	NOUN
aiua-13635	137	22	:	:	PUNCT
aiua-13635	137	23	v.s.	v.s.	ADJ
aiua-13635	137	24	,	,	PUNCT
aiua-13635	137	25	p.p	p.p	PROPN
aiua-13635	137	26	.	.	PROPN
aiua-13635	137	27	,	,	PUNCT
aiua-13635	137	28	p.l	p.l	PROPN
aiua-13635	137	29	.	.	PROPN
aiua-13635	137	30	;	;	PUNCT
aiua-13635	137	31	methodology	methodology	NOUN
aiua-13635	137	32	:	:	PUNCT
aiua-13635	137	33	v.s.	v.s.	X
aiua-13635	137	34	,	,	PUNCT
aiua-13635	137	35	p.p	p.p	PROPN
aiua-13635	137	36	.	.	PROPN
aiua-13635	137	37	,	,	PUNCT
aiua-13635	137	38	p.l	p.l	PROPN
aiua-13635	137	39	.	.	PROPN
aiua-13635	137	40	;	;	PUNCT
aiua-13635	137	41	resources	resource	NOUN
aiua-13635	137	42	:	:	PUNCT
aiua-13635	137	43	v.s.	v.s.	ADJ
aiua-13635	137	44	,	,	PUNCT
aiua-13635	137	45	p.p	p.p	PROPN
aiua-13635	137	46	.	.	PROPN
aiua-13635	137	47	,	,	PUNCT
aiua-13635	137	48	p.l	p.l	PROPN
aiua-13635	137	49	.	.	PROPN
aiua-13635	137	50	,	,	PUNCT
aiua-13635	137	51	f.f	f.f	PROPN
aiua-13635	137	52	.	.	PROPN
aiua-13635	137	53	;	;	PUNCT
aiua-13635	137	54	software	software	NOUN
aiua-13635	137	55	:	:	PUNCT
aiua-13635	137	56	v.s.	v.s.	ADJ
aiua-13635	137	57	,	,	PUNCT
aiua-13635	137	58	p.p	p.p	PROPN
aiua-13635	137	59	.	.	PROPN
aiua-13635	137	60	,	,	PUNCT
aiua-13635	137	61	p.l	p.l	PROPN
aiua-13635	137	62	.	.	PROPN
aiua-13635	137	63	,	,	PUNCT
aiua-13635	137	64	f.f	f.f	PROPN
aiua-13635	137	65	.	.	PROPN
aiua-13635	137	66	,	,	PUNCT
aiua-13635	137	67	v.n	v.n	PROPN
aiua-13635	137	68	.	.	PROPN
aiua-13635	137	69	,	,	PUNCT
aiua-13635	137	70	a.c	a.c	PROPN
aiua-13635	137	71	.	.	PROPN
aiua-13635	137	72	,	,	PUNCT
aiua-13635	137	73	c.a	c.a	PROPN
aiua-13635	137	74	.	.	PROPN
aiua-13635	137	75	,	,	PUNCT
aiua-13635	137	76	t.c	t.c	PROPN
aiua-13635	137	77	.	.	PROPN
aiua-13635	137	78	,	,	PUNCT
aiua-13635	137	79	s.r	s.r	PROPN
aiua-13635	137	80	.	.	PROPN
aiua-13635	137	81	,	,	PUNCT
aiua-13635	137	82	m.c	m.c	PROPN
aiua-13635	137	83	.	.	PROPN
aiua-13635	137	84	;	;	PUNCT
aiua-13635	137	85	writing	write	VERB
aiua-13635	137	86	original	original	ADJ
aiua-13635	137	87	draft	draft	NOUN
aiua-13635	137	88	:	:	PUNCT
aiua-13635	137	89	v.s.	v.s.	ADJ
aiua-13635	137	90	,	,	PUNCT
aiua-13635	137	91	p.p	p.p	PROPN
aiua-13635	137	92	.	.	PROPN
aiua-13635	137	93	,	,	PUNCT
aiua-13635	137	94	p.l	p.l	PROPN
aiua-13635	137	95	.	.	PROPN
aiua-13635	137	96	;	;	PUNCT
aiua-13635	137	97	writing	write	VERB
aiua-13635	137	98	review	review	NOUN
aiua-13635	137	99	&	&	CCONJ
aiua-13635	137	100	editing	editing	PROPN
aiua-13635	137	101	:	:	PUNCT
aiua-13635	137	102	v.s.	v.s.	ADJ
aiua-13635	137	103	,	,	PUNCT
aiua-13635	137	104	p.p	p.p	PROPN
aiua-13635	137	105	.	.	PROPN
aiua-13635	137	106	,	,	PUNCT
aiua-13635	137	107	p.l	p.l	PROPN
aiua-13635	137	108	.	.	PROPN
aiua-13635	137	109	,	,	PUNCT
aiua-13635	137	110	f.f	f.f	PROPN
aiua-13635	137	111	.	.	PROPN
aiua-13635	137	112	funding	funding	NOUN
aiua-13635	137	113	acquisition	acquisition	NOUN
aiua-13635	137	114	:	:	PUNCT
aiua-13635	137	115	none	none	NOUN
aiua-13635	137	116	.	.	PUNCT
aiua-13635	138	1	consent	consent	NOUN
aiua-13635	138	2	for	for	ADP
aiua-13635	138	3	publication	publication	NOUN
aiua-13635	138	4	:	:	PUNCT
aiua-13635	138	5	all	all	DET
aiua-13635	138	6	authors	author	NOUN
aiua-13635	138	7	have	have	AUX
aiua-13635	138	8	read	read	VERB
aiua-13635	138	9	and	and	CCONJ
aiua-13635	138	10	approved	approve	VERB
aiua-13635	138	11	the	the	DET
aiua-13635	138	12	content	content	NOUN
aiua-13635	138	13	and	and	CCONJ
aiua-13635	138	14	agree	agree	VERB
aiua-13635	138	15	to	to	PART
aiua-13635	138	16	submit	submit	VERB
aiua-13635	138	17	for	for	ADP
aiua-13635	138	18	consideration	consideration	NOUN
aiua-13635	138	19	for	for	ADP
aiua-13635	138	20	publication	publication	NOUN
aiua-13635	138	21	in	in	ADP
aiua-13635	138	22	the	the	DET
aiua-13635	138	23	journal	journal	NOUN
aiua-13635	138	24	.	.	PUNCT
aiua-13635	139	1	acknowledgments	acknowledgment	NOUN
aiua-13635	139	2	:	:	PUNCT
aiua-13635	139	3	none	none	NOUN
aiua-13635	139	4	.	.	PUNCT
aiua-13635	140	1	archivio	archivio	NOUN
aiua-13635	140	2	italiano	italiano	PROPN
aiua-13635	140	3	di	di	PROPN
aiua-13635	140	4	urologia	urologia	PROPN
aiua-13635	140	5	e	e	PROPN
aiua-13635	140	6	andrologia	andrologia	NOUN
aiua-13635	140	7	2025	2025	NUM
aiua-13635	140	8	;	;	PUNCT
aiua-13635	140	9	97(2):13635	97(2):13635	NUM
aiua-13635	140	10	5	5	NUM
aiua-13635	140	11	prostate	prostate	NOUN
aiua-13635	140	12	cancer	cancer	NOUN
aiua-13635	140	13	and	and	CCONJ
aiua-13635	140	14	brca	brca	PROPN
aiua-13635	140	15	mutations	mutation	NOUN
aiua-13635	140	16	68ga	68ga	ADJ
aiua-13635	140	17	-	-	PUNCT
aiua-13635	140	18	psma	psma	NOUN
aiua-13635	140	19	pet	pet	NOUN
aiua-13635	140	20	/	/	SYM
aiua-13635	140	21	ct	ct	PROPN
aiua-13635	140	22	vs.	vs.	X
aiua-13635	140	23	mpmri	mpmri	PROPN
aiua-13635	140	24	in	in	ADP
aiua-13635	140	25	the	the	DET
aiua-13635	140	26	diagnosis	diagnosis	NOUN
aiua-13635	140	27	of	of	ADP
aiua-13635	140	28	prostate	prostate	NOUN
aiua-13635	140	29	cancer	cancer	NOUN
aiua-13635	140	30	.	.	PUNCT
aiua-13635	141	1	arch	arch	PROPN
aiua-13635	141	2	ital	ital	PROPN
aiua-13635	141	3	urol	urol	PROPN
aiua-13635	141	4	androl	androl	PROPN
aiua-13635	141	5	.	.	PROPN
aiua-13635	141	6	2022	2022	NUM
aiua-13635	141	7	;	;	PUNCT
aiua-13635	141	8	94:274	94:274	NUM
aiua-13635	141	9	-	-	SYM
aiua-13635	141	10	277	277	NUM
aiua-13635	141	11	.	.	PUNCT
aiua-13635	142	1	20	20	NUM
aiua-13635	142	2	.	.	PUNCT
aiua-13635	143	1	pepe	pepe	PROPN
aiua-13635	143	2	p	p	PROPN
aiua-13635	143	3	,	,	PUNCT
aiua-13635	143	4	pennisi	pennisi	VERB
aiua-13635	143	5	m.	m.	NOUN
aiua-13635	143	6	should	should	AUX
aiua-13635	143	7	68ga	68ga	ADJ
aiua-13635	143	8	-	-	PUNCT
aiua-13635	143	9	psma	psma	NOUN
aiua-13635	143	10	pet	pet	NOUN
aiua-13635	143	11	/	/	SYM
aiua-13635	143	12	ct	ct	PROPN
aiua-13635	143	13	replace	replace	NOUN
aiua-13635	143	14	ct	ct	NOUN
aiua-13635	143	15	and	and	CCONJ
aiua-13635	143	16	bone	bone	NOUN
aiua-13635	143	17	scan	scan	NOUN
aiua-13635	143	18	in	in	ADP
aiua-13635	143	19	clinical	clinical	ADJ
aiua-13635	143	20	staging	staging	NOUN
aiua-13635	143	21	of	of	ADP
aiua-13635	143	22	high	high	ADJ
aiua-13635	143	23	-	-	PUNCT
aiua-13635	143	24	risk	risk	NOUN
aiua-13635	143	25	prostate	prostate	NOUN
aiua-13635	143	26	cancer	cancer	NOUN
aiua-13635	143	27	?	?	PUNCT
aiua-13635	144	1	anticancer	anticancer	NOUN
aiua-13635	144	2	res	re	NOUN
aiua-13635	144	3	.	.	PUNCT
aiua-13635	144	4	2022	2022	NUM
aiua-13635	144	5	;	;	PUNCT
aiua-13635	144	6	42:1495	42:1495	NUM
aiua-13635	144	7	-	-	SYM
aiua-13635	144	8	1498	1498	NUM
aiua-13635	144	9	.	.	PUNCT
aiua-13635	145	1	21	21	NUM
aiua-13635	145	2	.	.	PUNCT
aiua-13635	145	3	pepe	pepe	PROPN
aiua-13635	145	4	p	p	PROPN
aiua-13635	145	5	,	,	PUNCT
aiua-13635	145	6	pepe	pepe	PROPN
aiua-13635	145	7	l	l	PROPN
aiua-13635	145	8	,	,	PUNCT
aiua-13635	145	9	fiorentino	fiorentino	PROPN
aiua-13635	145	10	v	v	NOUN
aiua-13635	145	11	,	,	PUNCT
aiua-13635	145	12	et	et	PROPN
aiua-13635	145	13	al	al	PROPN
aiua-13635	145	14	.	.	PROPN
aiua-13635	145	15	psma	psma	PROPN
aiua-13635	145	16	pet	pet	PROPN
aiua-13635	145	17	/	/	SYM
aiua-13635	145	18	ct	ct	PROPN
aiua-13635	145	19	accuracy	accuracy	NOUN
aiua-13635	145	20	in	in	ADP
aiua-13635	145	21	diagnosing	diagnose	VERB
aiua-13635	145	22	prostate	prostate	NOUN
aiua-13635	145	23	cancer	cancer	NOUN
aiua-13635	145	24	nodes	node	NOUN
aiua-13635	145	25	metastases	metastasis	NOUN
aiua-13635	145	26	.	.	PUNCT
aiua-13635	146	1	in	in	ADP
aiua-13635	146	2	vivo	vivo	NOUN
aiua-13635	146	3	.	.	PUNCT
aiua-13635	147	1	2024	2024	NUM
aiua-13635	147	2	;	;	PUNCT
aiua-13635	147	3	38:2880	38:2880	PROPN
aiua-13635	147	4	-	-	SYM
aiua-13635	147	5	2885	2885	NUM
aiua-13635	147	6	.	.	PUNCT
aiua-13635	148	1	22	22	NUM
aiua-13635	148	2	.	.	PUNCT
aiua-13635	149	1	kechin	kechin	PROPN
aiua-13635	149	2	a	a	DET
aiua-13635	149	3	,	,	PUNCT
aiua-13635	149	4	khrapov	khrapov	PROPN
aiua-13635	149	5	e	e	PROPN
aiua-13635	149	6	,	,	PUNCT
aiua-13635	149	7	boyarskikh	boyarskikh	NOUN
aiua-13635	149	8	u	u	NOUN
aiua-13635	149	9	,	,	PUNCT
aiua-13635	149	10	et	et	PROPN
aiua-13635	149	11	al	al	PROPN
aiua-13635	149	12	.	.	PROPN
aiua-13635	149	13	brca	brca	PROPN
aiua-13635	149	14	-	-	PUNCT
aiua-13635	149	15	analyzer	analyzer	NOUN
aiua-13635	149	16	:	:	PUNCT
aiua-13635	149	17	automatic	automatic	ADJ
aiua-13635	149	18	workflow	workflow	NOUN
aiua-13635	149	19	for	for	ADP
aiua-13635	149	20	processing	processing	NOUN
aiua-13635	149	21	ngs	ng	NOUN
aiua-13635	149	22	reads	read	NOUN
aiua-13635	149	23	of	of	ADP
aiua-13635	149	24	brca1	brca1	PROPN
aiua-13635	149	25	and	and	CCONJ
aiua-13635	149	26	brca2	brca2	NOUN
aiua-13635	149	27	genes	gene	NOUN
aiua-13635	149	28	.	.	PUNCT
aiua-13635	150	1	comput	comput	VERB
aiua-13635	150	2	biol	biol	PROPN
aiua-13635	150	3	chem	chem	NOUN
aiua-13635	150	4	.	.	PUNCT
aiua-13635	151	1	2018	2018	NUM
aiua-13635	151	2	;	;	PUNCT
aiua-13635	151	3	77:297	77:297	NUM
aiua-13635	151	4	-	-	SYM
aiua-13635	151	5	306	306	NUM
aiua-13635	151	6	.	.	PUNCT
aiua-13635	152	1	23	23	NUM
aiua-13635	152	2	.	.	PUNCT
aiua-13635	153	1	kalampokis	kalampokis	PROPN
aiua-13635	153	2	n	n	CCONJ
aiua-13635	153	3	,	,	PUNCT
aiua-13635	153	4	zabaftis	zabaftis	PROPN
aiua-13635	153	5	c	c	PROPN
aiua-13635	153	6	,	,	PUNCT
aiua-13635	153	7	spinos	spinos	PROPN
aiua-13635	153	8	t	t	PROPN
aiua-13635	153	9	,	,	PUNCT
aiua-13635	153	10	et	et	PROPN
aiua-13635	153	11	al	al	PROPN
aiua-13635	153	12	.	.	PROPN
aiua-13635	153	13	review	review	NOUN
aiua-13635	153	14	on	on	ADP
aiua-13635	153	15	the	the	DET
aiua-13635	153	16	role	role	NOUN
aiua-13635	153	17	of	of	ADP
aiua-13635	153	18	brca	brca	PROPN
aiua-13635	153	19	mutations	mutation	NOUN
aiua-13635	153	20	in	in	ADP
aiua-13635	153	21	genomic	genomic	ADJ
aiua-13635	153	22	screening	screening	NOUN
aiua-13635	153	23	and	and	CCONJ
aiua-13635	153	24	risk	risk	NOUN
aiua-13635	153	25	stratification	stratification	NOUN
aiua-13635	153	26	of	of	ADP
aiua-13635	153	27	prostate	prostate	NOUN
aiua-13635	153	28	cancer	cancer	NOUN
aiua-13635	153	29	.	.	PUNCT
aiua-13635	154	1	curr	curr	PROPN
aiua-13635	154	2	oncol	oncol	PROPN
aiua-13635	154	3	.	.	PUNCT
aiua-13635	155	1	2024	2024	NUM
aiua-13635	155	2	;	;	PUNCT
aiua-13635	155	3	31:1162	31:1162	NUM
aiua-13635	155	4	-	-	SYM
aiua-13635	155	5	1169	1169	NUM
aiua-13635	155	6	.	.	PUNCT
aiua-13635	156	1	24	24	NUM
aiua-13635	156	2	.	.	PUNCT
aiua-13635	157	1	giri	giri	PROPN
aiua-13635	157	2	vn	vn	PROPN
aiua-13635	157	3	,	,	PUNCT
aiua-13635	157	4	knudsen	knudsen	PROPN
aiua-13635	157	5	ke	ke	PROPN
aiua-13635	157	6	,	,	PUNCT
aiua-13635	157	7	kelly	kelly	PROPN
aiua-13635	157	8	wk	wk	PROPN
aiua-13635	157	9	,	,	PUNCT
aiua-13635	157	10	et	et	PROPN
aiua-13635	157	11	al	al	PROPN
aiua-13635	157	12	.	.	PUNCT
aiua-13635	158	1	implementation	implementation	NOUN
aiua-13635	158	2	of	of	ADP
aiua-13635	158	3	germline	germline	NOUN
aiua-13635	158	4	testing	testing	NOUN
aiua-13635	158	5	for	for	ADP
aiua-13635	158	6	prostate	prostate	NOUN
aiua-13635	158	7	cancer	cancer	NOUN
aiua-13635	158	8	:	:	PUNCT
aiua-13635	158	9	philadelphia	philadelphia	PROPN
aiua-13635	158	10	prostate	prostate	NOUN
aiua-13635	158	11	cancer	cancer	NOUN
aiua-13635	158	12	consensus	consensus	NOUN
aiua-13635	158	13	conference	conference	NOUN
aiua-13635	158	14	2019	2019	NUM
aiua-13635	158	15	.	.	PUNCT
aiua-13635	159	1	j	j	PROPN
aiua-13635	159	2	clin	clin	PROPN
aiua-13635	159	3	oncol	oncol	PROPN
aiua-13635	159	4	.	.	PUNCT
aiua-13635	160	1	2020	2020	NUM
aiua-13635	160	2	;	;	PUNCT
aiua-13635	160	3	38:2798	38:2798	NUM
aiua-13635	160	4	-	-	SYM
aiua-13635	160	5	2811	2811	NUM
aiua-13635	160	6	.	.	PUNCT
aiua-13635	161	1	25	25	NUM
aiua-13635	161	2	.	.	PUNCT
aiua-13635	162	1	pepe	pepe	PROPN
aiua-13635	162	2	p	p	PROPN
aiua-13635	162	3	,	,	PUNCT
aiua-13635	162	4	aragona	aragona	PROPN
aiua-13635	162	5	f.	f.	PROPN
aiua-13635	162	6	prostate	prostate	PROPN
aiua-13635	162	7	needle	needle	PROPN
aiua-13635	162	8	biopsy	biopsy	NOUN
aiua-13635	162	9	:	:	PUNCT
aiua-13635	162	10	12	12	NUM
aiua-13635	162	11	vs.	vs.	ADP
aiua-13635	162	12	18	18	NUM
aiua-13635	162	13	cores	core	NOUN
aiua-13635	162	14	-is	-is	ADP
aiua-13635	162	15	it	it	PRON
aiua-13635	162	16	necessary	necessary	ADJ
aiua-13635	162	17	?	?	PUNCT
aiua-13635	163	1	urol	urol	PROPN
aiua-13635	163	2	int	int	PROPN
aiua-13635	163	3	.	.	PUNCT
aiua-13635	164	1	2005	2005	NUM
aiua-13635	164	2	;	;	PUNCT
aiua-13635	164	3	74:19	74:19	NUM
aiua-13635	164	4	-	-	SYM
aiua-13635	164	5	22	22	NUM
aiua-13635	164	6	.	.	PUNCT
aiua-13635	165	1	26	26	NUM
aiua-13635	165	2	.	.	PUNCT
aiua-13635	166	1	pepe	pepe	PROPN
aiua-13635	166	2	p	p	PROPN
aiua-13635	166	3	,	,	PUNCT
aiua-13635	166	4	pennisi	pennisi	VERB
aiua-13635	166	5	m.	m.	NOUN
aiua-13635	166	6	morbidity	morbidity	NOUN
aiua-13635	166	7	following	follow	VERB
aiua-13635	166	8	transperineal	transperineal	NOUN
aiua-13635	166	9	prostate	prostate	NOUN
aiua-13635	166	10	biopsy	biopsy	NOUN
aiua-13635	166	11	:	:	PUNCT
aiua-13635	166	12	our	our	PRON
aiua-13635	166	13	experience	experience	NOUN
aiua-13635	166	14	in	in	ADP
aiua-13635	166	15	8.500	8.500	NUM
aiua-13635	166	16	men	man	NOUN
aiua-13635	166	17	.	.	PUNCT
aiua-13635	167	1	arch	arch	ADJ
aiua-13635	167	2	ital	ital	PROPN
aiua-13635	167	3	urol	urol	PROPN
aiua-13635	167	4	androl	androl	PROPN
aiua-13635	167	5	.	.	PROPN
aiua-13635	167	6	2022	2022	NUM
aiua-13635	167	7	;	;	PUNCT
aiua-13635	167	8	94:155	94:155	NUM
aiua-13635	167	9	-	-	SYM
aiua-13635	167	10	159	159	NUM
aiua-13635	167	11	.	.	PUNCT
aiua-13635	167	12	27	27	NUM
aiua-13635	167	13	.	.	PUNCT
aiua-13635	168	1	robinson	robinson	PROPN
aiua-13635	168	2	d	d	PROPN
aiua-13635	168	3	,	,	PUNCT
aiua-13635	168	4	van	van	PROPN
aiua-13635	168	5	allen	allen	PROPN
aiua-13635	168	6	em	em	PRON
aiua-13635	168	7	,	,	PUNCT
aiua-13635	168	8	wu	wu	PROPN
aiua-13635	168	9	ym	ym	PROPN
aiua-13635	168	10	,	,	PUNCT
aiua-13635	168	11	et	et	PROPN
aiua-13635	169	1	al	al	PROPN
aiua-13635	169	2	.	.	PROPN
aiua-13635	169	3	integrative	integrative	ADJ
aiua-13635	169	4	clinical	clinical	ADJ
aiua-13635	169	5	genomics	genomic	NOUN
aiua-13635	169	6	of	of	ADP
aiua-13635	169	7	advanced	advanced	ADJ
aiua-13635	169	8	prostate	prostate	NOUN
aiua-13635	169	9	cancer	cancer	NOUN
aiua-13635	169	10	.	.	PUNCT
aiua-13635	170	1	cell	cell	NOUN
aiua-13635	170	2	.	.	PUNCT
aiua-13635	171	1	2015	2015	NUM
aiua-13635	171	2	;	;	PUNCT
aiua-13635	171	3	161:1215	161:1215	NUM
aiua-13635	171	4	-	-	SYM
aiua-13635	171	5	1228	1228	NUM
aiua-13635	171	6	.	.	PUNCT
aiua-13635	172	1	28	28	NUM
aiua-13635	172	2	.	.	PUNCT
aiua-13635	173	1	hommerding	hommerde	VERB
aiua-13635	173	2	m	m	PRON
aiua-13635	173	3	,	,	PUNCT
aiua-13635	173	4	hommerding	hommerde	VERB
aiua-13635	173	5	o	o	NOUN
aiua-13635	173	6	,	,	PUNCT
aiua-13635	173	7	bernhardt	bernhardt	PROPN
aiua-13635	173	8	m	m	PROPN
aiua-13635	173	9	,	,	PUNCT
aiua-13635	173	10	et	et	PROPN
aiua-13635	173	11	al	al	PROPN
aiua-13635	173	12	.	.	PUNCT
aiua-13635	174	1	real	real	ADJ
aiua-13635	174	2	-	-	PUNCT
aiua-13635	174	3	world	world	NOUN
aiua-13635	174	4	data	datum	NOUN
aiua-13635	174	5	on	on	ADP
aiua-13635	174	6	the	the	DET
aiua-13635	174	7	prevalence	prevalence	NOUN
aiua-13635	174	8	of	of	ADP
aiua-13635	174	9	brca1/2	brca1/2	PROPN
aiua-13635	174	10	and	and	CCONJ
aiua-13635	174	11	hrr	hrr	PROPN
aiua-13635	174	12	gene	gene	NOUN
aiua-13635	174	13	mutations	mutation	NOUN
aiua-13635	174	14	in	in	ADP
aiua-13635	174	15	patients	patient	NOUN
aiua-13635	174	16	with	with	ADP
aiua-13635	174	17	primary	primary	ADJ
aiua-13635	174	18	and	and	CCONJ
aiua-13635	174	19	metastatic	metastatic	ADJ
aiua-13635	174	20	castration	castration	NOUN
aiua-13635	174	21	resistant	resistant	ADJ
aiua-13635	174	22	prostate	prostate	NOUN
aiua-13635	174	23	cancer	cancer	NOUN
aiua-13635	174	24	.	.	PUNCT
aiua-13635	175	1	world	world	PROPN
aiua-13635	175	2	j	j	PROPN
aiua-13635	175	3	urol	urol	PROPN
aiua-13635	175	4	.	.	PUNCT
aiua-13635	176	1	2024	2024	NUM
aiua-13635	176	2	;	;	PUNCT
aiua-13635	176	3	42:491	42:491	NUM
aiua-13635	176	4	.	.	NOUN
aiua-13635	177	1	29	29	NUM
aiua-13635	177	2	.	.	PUNCT
aiua-13635	178	1	bancroft	bancroft	PROPN
aiua-13635	178	2	ek	ek	PROPN
aiua-13635	178	3	,	,	PUNCT
aiua-13635	178	4	page	page	NOUN
aiua-13635	178	5	ec	ec	PROPN
aiua-13635	178	6	,	,	PUNCT
aiua-13635	178	7	castro	castro	PROPN
aiua-13635	178	8	e	e	PROPN
aiua-13635	178	9	,	,	PUNCT
aiua-13635	178	10	et	et	PROPN
aiua-13635	178	11	al	al	PROPN
aiua-13635	178	12	.	.	PROPN
aiua-13635	178	13	targeted	target	VERB
aiua-13635	178	14	prostate	prostate	NOUN
aiua-13635	178	15	cancer	cancer	NOUN
aiua-13635	178	16	screening	screening	NOUN
aiua-13635	178	17	in	in	ADP
aiua-13635	178	18	brca1	brca1	PROPN
aiua-13635	178	19	and	and	CCONJ
aiua-13635	178	20	brca2	brca2	PROPN
aiua-13635	178	21	mutation	mutation	NOUN
aiua-13635	178	22	carriers	carrier	NOUN
aiua-13635	178	23	:	:	PUNCT
aiua-13635	178	24	results	result	NOUN
aiua-13635	178	25	from	from	ADP
aiua-13635	178	26	the	the	DET
aiua-13635	178	27	initial	initial	ADJ
aiua-13635	178	28	screening	screening	NOUN
aiua-13635	178	29	round	round	NOUN
aiua-13635	178	30	of	of	ADP
aiua-13635	178	31	the	the	DET
aiua-13635	178	32	impact	impact	NOUN
aiua-13635	178	33	study	study	NOUN
aiua-13635	178	34	.	.	PUNCT
aiua-13635	179	1	eur	eur	PROPN
aiua-13635	179	2	urol	urol	PROPN
aiua-13635	179	3	.	.	PUNCT
aiua-13635	179	4	2014	2014	NUM
aiua-13635	179	5	;	;	PUNCT
aiua-13635	179	6	66:489	66:489	NUM
aiua-13635	179	7	-	-	SYM
aiua-13635	179	8	499	499	NUM
aiua-13635	179	9	.	.	PUNCT
aiua-13635	179	10	30	30	NUM
aiua-13635	179	11	.	.	PUNCT
aiua-13635	180	1	carter	carter	PROPN
aiua-13635	180	2	hb	hb	PROPN
aiua-13635	180	3	,	,	PUNCT
aiua-13635	180	4	helfand	helfand	NOUN
aiua-13635	180	5	b	b	NOUN
aiua-13635	180	6	,	,	PUNCT
aiua-13635	180	7	mamawala	mamawala	PROPN
aiua-13635	180	8	m	m	PROPN
aiua-13635	180	9	,	,	PUNCT
aiua-13635	180	10	et	et	PROPN
aiua-13635	180	11	al	al	PROPN
aiua-13635	180	12	.	.	PROPN
aiua-13635	180	13	germline	germline	NOUN
aiua-13635	180	14	mutations	mutation	NOUN
aiua-13635	180	15	in	in	ADP
aiua-13635	180	16	atm	atm	NOUN
aiua-13635	180	17	and	and	CCONJ
aiua-13635	180	18	brca1/2	brca1/2	PROPN
aiua-13635	180	19	are	be	AUX
aiua-13635	180	20	associated	associate	VERB
aiua-13635	180	21	with	with	ADP
aiua-13635	180	22	grade	grade	NOUN
aiua-13635	180	23	reclassification	reclassification	NOUN
aiua-13635	180	24	in	in	ADP
aiua-13635	180	25	men	man	NOUN
aiua-13635	180	26	on	on	ADP
aiua-13635	180	27	active	active	ADJ
aiua-13635	180	28	surveillance	surveillance	NOUN
aiua-13635	180	29	for	for	ADP
aiua-13635	180	30	prostate	prostate	NOUN
aiua-13635	180	31	cancer	cancer	NOUN
aiua-13635	180	32	.	.	PUNCT
aiua-13635	181	1	eur	eur	PROPN
aiua-13635	181	2	urol	urol	PROPN
aiua-13635	181	3	.	.	PROPN
aiua-13635	182	1	2019	2019	NUM
aiua-13635	182	2	;	;	PUNCT
aiua-13635	182	3	75:743	75:743	NUM
aiua-13635	182	4	-	-	SYM
aiua-13635	182	5	749	749	NUM
aiua-13635	182	6	.	.	PUNCT
aiua-13635	183	1	31	31	NUM
aiua-13635	183	2	.	.	PUNCT
aiua-13635	184	1	pepe	pepe	PROPN
aiua-13635	184	2	p	p	PROPN
aiua-13635	184	3	,	,	PUNCT
aiua-13635	184	4	cimino	cimino	PROPN
aiua-13635	184	5	s	s	PROPN
aiua-13635	184	6	,	,	PUNCT
aiua-13635	184	7	garufi	garufi	PROPN
aiua-13635	184	8	a	a	X
aiua-13635	184	9	,	,	PUNCT
aiua-13635	184	10	et	et	PROPN
aiua-13635	184	11	al	al	PROPN
aiua-13635	184	12	.	.	PUNCT
aiua-13635	184	13	detection	detection	NOUN
aiua-13635	184	14	rate	rate	NOUN
aiua-13635	184	15	for	for	ADP
aiua-13635	184	16	significant	significant	ADJ
aiua-13635	184	17	cancer	cancer	NOUN
aiua-13635	184	18	at	at	ADP
aiua-13635	184	19	confirmatory	confirmatory	NOUN
aiua-13635	184	20	biopsy	biopsy	NOUN
aiua-13635	184	21	in	in	ADP
aiua-13635	184	22	men	man	NOUN
aiua-13635	184	23	enrolled	enrol	VERB
aiua-13635	184	24	in	in	ADP
aiua-13635	184	25	active	active	ADJ
aiua-13635	184	26	surveillance	surveillance	NOUN
aiua-13635	184	27	protocol	protocol	NOUN
aiua-13635	184	28	:	:	PUNCT
aiua-13635	184	29	20	20	NUM
aiua-13635	184	30	cores	core	NOUN
aiua-13635	184	31	vs	vs	ADP
aiua-13635	184	32	30	30	NUM
aiua-13635	184	33	cores	core	NOUN
aiua-13635	184	34	vs	vs	ADP
aiua-13635	184	35	mri	mri	NOUN
aiua-13635	184	36	/	/	SYM
aiua-13635	184	37	trus	trus	NOUN
aiua-13635	184	38	fusion	fusion	NOUN
aiua-13635	184	39	prostate	prostate	NOUN
aiua-13635	184	40	biopsy	biopsy	NOUN
aiua-13635	184	41	.	.	PUNCT
aiua-13635	185	1	arch	arch	ADJ
aiua-13635	185	2	ital	ital	PROPN
aiua-13635	185	3	urol	urol	PROPN
aiua-13635	185	4	androl	androl	PROPN
aiua-13635	185	5	.	.	PROPN
aiua-13635	185	6	2016	2016	NUM
aiua-13635	185	7	;	;	PUNCT
aiua-13635	185	8	88:300	88:300	NUM
aiua-13635	185	9	-	-	SYM
aiua-13635	185	10	303	303	NUM
aiua-13635	185	11	.	.	PUNCT
aiua-13635	186	1	32	32	NUM
aiua-13635	186	2	.	.	PUNCT
aiua-13635	187	1	pepe	pepe	PROPN
aiua-13635	187	2	p	p	PROPN
aiua-13635	187	3	,	,	PUNCT
aiua-13635	187	4	roscigno	roscigno	PROPN
aiua-13635	187	5	m	m	PROPN
aiua-13635	187	6	,	,	PUNCT
aiua-13635	187	7	pepe	pepe	PROPN
aiua-13635	187	8	l	l	PROPN
aiua-13635	187	9	,	,	PUNCT
aiua-13635	187	10	et	et	PROPN
aiua-13635	187	11	al	al	PROPN
aiua-13635	187	12	.	.	PROPN
aiua-13635	188	1	could	could	AUX
aiua-13635	188	2	68ga	68ga	ADV
aiua-13635	188	3	-	-	PUNCT
aiua-13635	188	4	psma	psma	NOUN
aiua-13635	188	5	pet	pet	NOUN
aiua-13635	188	6	/	/	SYM
aiua-13635	188	7	ct	ct	PROPN
aiua-13635	188	8	evaluation	evaluation	NOUN
aiua-13635	188	9	reduce	reduce	VERB
aiua-13635	188	10	the	the	DET
aiua-13635	188	11	number	number	NOUN
aiua-13635	188	12	of	of	ADP
aiua-13635	188	13	scheduled	schedule	VERB
aiua-13635	188	14	prostate	prostate	NOUN
aiua-13635	188	15	biopsies	biopsy	NOUN
aiua-13635	188	16	in	in	ADP
aiua-13635	188	17	men	man	NOUN
aiua-13635	188	18	enrolled	enrol	VERB
aiua-13635	188	19	in	in	ADP
aiua-13635	188	20	active	active	ADJ
aiua-13635	188	21	surveillance	surveillance	NOUN
aiua-13635	188	22	protocols	protocol	NOUN
aiua-13635	188	23	?	?	PUNCT
aiua-13635	189	1	j	j	PROPN
aiua-13635	189	2	clin	clin	PROPN
aiua-13635	189	3	med	med	PROPN
aiua-13635	189	4	.	.	PUNCT
aiua-13635	189	5	2022	2022	NUM
aiua-13635	189	6	;	;	PUNCT
aiua-13635	189	7	11:3473	11:3473	NUM
aiua-13635	189	8	.	.	X
aiua-13635	190	1	33	33	NUM
aiua-13635	190	2	.	.	PUNCT
aiua-13635	191	1	pepe	pepe	PROPN
aiua-13635	191	2	p	p	PROPN
aiua-13635	191	3	,	,	PUNCT
aiua-13635	191	4	pennisi	pennisi	VERB
aiua-13635	191	5	m	m	PROPN
aiua-13635	191	6	,	,	PUNCT
aiua-13635	191	7	fraggetta	fraggetta	PROPN
aiua-13635	191	8	f.	f.	PROPN
aiua-13635	192	1	how	how	SCONJ
aiua-13635	192	2	many	many	ADJ
aiua-13635	192	3	cores	core	NOUN
aiua-13635	192	4	should	should	AUX
aiua-13635	192	5	be	be	AUX
aiua-13635	192	6	obtained	obtain	VERB
aiua-13635	192	7	during	during	ADP
aiua-13635	192	8	saturation	saturation	NOUN
aiua-13635	192	9	biopsy	biopsy	NOUN
aiua-13635	192	10	in	in	ADP
aiua-13635	192	11	the	the	DET
aiua-13635	192	12	era	era	NOUN
aiua-13635	192	13	of	of	ADP
aiua-13635	192	14	multiparametric	multiparametric	ADJ
aiua-13635	192	15	magnetic	magnetic	ADJ
aiua-13635	192	16	resonance	resonance	NOUN
aiua-13635	192	17	?	?	PUNCT
aiua-13635	193	1	experience	experience	NOUN
aiua-13635	193	2	in	in	ADP
aiua-13635	193	3	875	875	NUM
aiua-13635	193	4	patients	patient	NOUN
aiua-13635	193	5	submitted	submit	VERB
aiua-13635	193	6	to	to	PART
aiua-13635	193	7	repeat	repeat	VERB
aiua-13635	193	8	prostate	prostate	NOUN
aiua-13635	193	9	biopsy	biopsy	NOUN
aiua-13635	193	10	.	.	PUNCT
aiua-13635	194	1	urology	urology	NOUN
aiua-13635	194	2	.	.	PUNCT
aiua-13635	195	1	2020	2020	NUM
aiua-13635	195	2	;	;	PUNCT
aiua-13635	196	1	137:133	137:133	X
aiua-13635	196	2	-	-	SYM
aiua-13635	196	3	137	137	NUM
aiua-13635	196	4	.	.	PUNCT
aiua-13635	197	1	34	34	NUM
aiua-13635	197	2	.	.	PUNCT
aiua-13635	198	1	tilki	tilki	PROPN
aiua-13635	199	1	d	d	NOUN
aiua-13635	199	2	,	,	PUNCT
aiua-13635	199	3	van	van	PROPN
aiua-13635	199	4	den	den	PROPN
aiua-13635	199	5	bergh	bergh	PROPN
aiua-13635	199	6	rcn	rcn	PROPN
aiua-13635	199	7	,	,	PUNCT
aiua-13635	199	8	briers	brier	NOUN
aiua-13635	199	9	e	e	NOUN
aiua-13635	199	10	,	,	PUNCT
aiua-13635	199	11	et	et	PROPN
aiua-13635	199	12	al	al	PROPN
aiua-13635	199	13	.	.	PUNCT
aiua-13635	199	14	eau	eau	PROPN
aiua-13635	199	15	-	-	PUNCT
aiua-13635	199	16	eanmestro	eanmestro	VERB
aiua-13635	199	17	-	-	PUNCT
aiua-13635	199	18	esur	esur	ADJ
aiua-13635	199	19	-	-	PUNCT
aiua-13635	199	20	isup	isup	NOUN
aiua-13635	199	21	-	-	PUNCT
aiua-13635	199	22	siog	siog	NOUN
aiua-13635	199	23	guidelines	guideline	NOUN
aiua-13635	199	24	on	on	ADP
aiua-13635	199	25	prostate	prostate	NOUN
aiua-13635	199	26	cancer	cancer	NOUN
aiua-13635	199	27	.	.	PUNCT
aiua-13635	200	1	part	part	NOUN
aiua-13635	200	2	ii2024	ii2024	NOUN
aiua-13635	200	3	update	update	NOUN
aiua-13635	200	4	:	:	PUNCT
aiua-13635	200	5	treatment	treatment	NOUN
aiua-13635	200	6	of	of	ADP
aiua-13635	200	7	relapsing	relapse	VERB
aiua-13635	200	8	and	and	CCONJ
aiua-13635	200	9	metastatic	metastatic	ADJ
aiua-13635	200	10	prostate	prostate	NOUN
aiua-13635	200	11	cancer	cancer	NOUN
aiua-13635	200	12	.	.	PUNCT
aiua-13635	201	1	eur	eur	PROPN
aiua-13635	201	2	urol	urol	PROPN
aiua-13635	201	3	.	.	PUNCT
aiua-13635	201	4	2024	2024	NUM
aiua-13635	201	5	;	;	PUNCT
aiua-13635	201	6	86:164	86:164	NUM
aiua-13635	201	7	-	-	SYM
aiua-13635	201	8	182	182	NUM
aiua-13635	201	9	.	.	PUNCT
aiua-13635	201	10	35	35	NUM
aiua-13635	201	11	.	.	PUNCT
aiua-13635	202	1	schaeffer	schaeffer	VERB
aiua-13635	202	2	em	em	PRON
aiua-13635	202	3	,	,	PUNCT
aiua-13635	202	4	srinivas	srinivas	PROPN
aiua-13635	202	5	s	s	PROPN
aiua-13635	202	6	,	,	PUNCT
aiua-13635	202	7	adra	adra	PROPN
aiua-13635	202	8	n	n	CCONJ
aiua-13635	202	9	,	,	PUNCT
aiua-13635	202	10	et	et	PROPN
aiua-13635	202	11	al	al	PROPN
aiua-13635	202	12	.	.	PROPN
aiua-13635	202	13	prostate	prostate	NOUN
aiua-13635	202	14	cancer	cancer	NOUN
aiua-13635	202	15	,	,	PUNCT
aiua-13635	202	16	version	version	NOUN
aiua-13635	202	17	4.2023	4.2023	NUM
aiua-13635	202	18	,	,	PUNCT
aiua-13635	202	19	nccn	nccn	ADJ
aiua-13635	202	20	clinical	clinical	ADJ
aiua-13635	202	21	practice	practice	NOUN
aiua-13635	202	22	guidelines	guideline	NOUN
aiua-13635	202	23	in	in	ADP
aiua-13635	202	24	oncology	oncology	NOUN
aiua-13635	202	25	.	.	PUNCT
aiua-13635	203	1	j	j	PROPN
aiua-13635	203	2	natl	natl	PROPN
aiua-13635	203	3	compr	compr	PROPN
aiua-13635	203	4	canc	canc	PROPN
aiua-13635	203	5	netw	netw	PROPN
aiua-13635	203	6	.	.	PUNCT
aiua-13635	204	1	2023	2023	NUM
aiua-13635	204	2	;	;	PUNCT
aiua-13635	204	3	21	21	NUM
aiua-13635	204	4	:	:	PUNCT
aiua-13635	204	5	1067	1067	NUM
aiua-13635	204	6	-	-	SYM
aiua-13635	204	7	1096	1096	NUM
aiua-13635	204	8	.	.	PUNCT
aiua-13635	205	1	36	36	NUM
aiua-13635	205	2	.	.	PUNCT
aiua-13635	206	1	pepe	pepe	PROPN
aiua-13635	206	2	p	p	PROPN
aiua-13635	206	3	,	,	PUNCT
aiua-13635	206	4	fandella	fandella	PROPN
aiua-13635	206	5	a	a	PRON
aiua-13635	206	6	,	,	PUNCT
aiua-13635	206	7	barbera	barbera	NOUN
aiua-13635	206	8	m	m	PROPN
aiua-13635	206	9	,	,	PUNCT
aiua-13635	206	10	et	et	PROPN
aiua-13635	206	11	al	al	PROPN
aiua-13635	206	12	.	.	PROPN
aiua-13635	206	13	advances	advance	NOUN
aiua-13635	206	14	in	in	ADP
aiua-13635	206	15	radiology	radiology	NOUN
aiua-13635	206	16	and	and	CCONJ
aiua-13635	206	17	pathology	pathology	NOUN
aiua-13635	206	18	of	of	ADP
aiua-13635	206	19	prostate	prostate	NOUN
aiua-13635	206	20	cancer	cancer	NOUN
aiua-13635	206	21	:	:	PUNCT
aiua-13635	206	22	a	a	DET
aiua-13635	206	23	review	review	NOUN
aiua-13635	206	24	for	for	ADP
aiua-13635	206	25	the	the	DET
aiua-13635	206	26	pathologist	pathologist	NOUN
aiua-13635	206	27	.	.	PUNCT
aiua-13635	207	1	pathologic	pathologic	NOUN
aiua-13635	207	2	.	.	PUNCT
aiua-13635	208	1	2024	2024	NUM
aiua-13635	208	2	;	;	PUNCT
aiua-13635	208	3	116:1	116:1	NOUN
aiua-13635	208	4	-	-	SYM
aiua-13635	208	5	12	12	NUM
aiua-13635	208	6	.	.	PUNCT
aiua-13635	209	1	37	37	NUM
aiua-13635	209	2	.	.	PUNCT
aiua-13635	210	1	cimadamore	cimadamore	VERB
aiua-13635	210	2	a	a	PRON
aiua-13635	210	3	,	,	PUNCT
aiua-13635	210	4	rescigno	rescigno	NOUN
aiua-13635	210	5	p	p	X
aiua-13635	210	6	,	,	PUNCT
aiua-13635	210	7	conteduca	conteduca	NOUN
aiua-13635	210	8	v	v	NOUN
aiua-13635	210	9	,	,	PUNCT
aiua-13635	210	10	italian	italian	ADJ
aiua-13635	210	11	society	society	NOUN
aiua-13635	210	12	for	for	ADP
aiua-13635	210	13	urooncology	urooncology	NOUN
aiua-13635	210	14	(	(	PUNCT
aiua-13635	210	15	siuro	siuro	NOUN
aiua-13635	210	16	)	)	PUNCT
aiua-13635	210	17	.	.	PUNCT
aiua-13635	211	1	siuro	siuro	VERB
aiua-13635	211	2	best	good	ADJ
aiua-13635	211	3	practice	practice	NOUN
aiua-13635	211	4	recommendations	recommendation	NOUN
aiua-13635	211	5	to	to	PART
aiua-13635	211	6	optimize	optimize	VERB
aiua-13635	211	7	brca	brca	PROPN
aiua-13635	211	8	1/2	1/2	NUM
aiua-13635	211	9	gene	gene	NOUN
aiua-13635	211	10	testing	testing	NOUN
aiua-13635	211	11	from	from	ADP
aiua-13635	211	12	dna	dna	PROPN
aiua-13635	211	13	extracted	extract	VERB
aiua-13635	211	14	from	from	ADP
aiua-13635	211	15	bone	bone	NOUN
aiua-13635	211	16	biopsy	biopsy	NOUN
aiua-13635	211	17	in	in	ADP
aiua-13635	211	18	mcrpc	mcrpc	PROPN
aiua-13635	211	19	patients	patient	NOUN
aiua-13635	211	20	(	(	PUNCT
aiua-13635	211	21	brca	brca	PROPN
aiua-13635	211	22	optimal	optimal	ADJ
aiua-13635	211	23	bone	bone	NOUN
aiua-13635	211	24	biopsy	biopsy	NOUN
aiua-13635	211	25	procedure	procedure	NOUN
aiua-13635	211	26	:	:	PUNCT
aiua-13635	211	27	bop	bop	INTJ
aiua-13635	211	28	)	)	PUNCT
aiua-13635	211	29	.	.	PUNCT
aiua-13635	212	1	virchows	virchow	NOUN
aiua-13635	212	2	arch	arch	VERB
aiua-13635	212	3	.	.	PUNCT
aiua-13635	213	1	2023	2023	NUM
aiua-13635	213	2	;	;	PUNCT
aiua-13635	213	3	483:579	483:579	NUM
aiua-13635	213	4	-	-	PUNCT
aiua-13635	213	5	589	589	NUM
aiua-13635	213	6	.	.	PUNCT
aiua-13635	214	1	38	38	NUM
aiua-13635	214	2	.	.	PUNCT
aiua-13635	215	1	russo	russo	PROPN
aiua-13635	215	2	a	a	PRON
aiua-13635	215	3	,	,	PUNCT
aiua-13635	215	4	incorvaia	incorvaia	PROPN
aiua-13635	215	5	l	l	NOUN
aiua-13635	215	6	,	,	PUNCT
aiua-13635	215	7	capoluongo	capoluongo	NOUN
aiua-13635	215	8	e	e	NOUN
aiua-13635	215	9	,	,	PUNCT
aiua-13635	215	10	italian	italian	ADJ
aiua-13635	215	11	scientific	scientific	ADJ
aiua-13635	215	12	societies	society	NOUN
aiua-13635	215	13	.	.	PUNCT
aiua-13635	216	1	implementation	implementation	NOUN
aiua-13635	216	2	of	of	ADP
aiua-13635	216	3	preventive	preventive	ADJ
aiua-13635	216	4	and	and	CCONJ
aiua-13635	216	5	predictive	predictive	ADJ
aiua-13635	216	6	brca	brca	PROPN
aiua-13635	216	7	testing	testing	NOUN
aiua-13635	216	8	in	in	ADP
aiua-13635	216	9	patients	patient	NOUN
aiua-13635	216	10	with	with	ADP
aiua-13635	216	11	breast	breast	NOUN
aiua-13635	216	12	,	,	PUNCT
aiua-13635	216	13	ovarian	ovarian	ADJ
aiua-13635	216	14	,	,	PUNCT
aiua-13635	216	15	pancreatic	pancreatic	ADJ
aiua-13635	216	16	,	,	PUNCT
aiua-13635	216	17	and	and	CCONJ
aiua-13635	216	18	prostate	prostate	NOUN
aiua-13635	216	19	cancer	cancer	NOUN
aiua-13635	216	20	:	:	PUNCT
aiua-13635	216	21	a	a	DET
aiua-13635	216	22	position	position	NOUN
aiua-13635	216	23	paper	paper	NOUN
aiua-13635	216	24	of	of	ADP
aiua-13635	216	25	italian	italian	ADJ
aiua-13635	216	26	scientific	scientific	ADJ
aiua-13635	216	27	societies	society	NOUN
aiua-13635	216	28	.	.	PUNCT
aiua-13635	217	1	esmo	esmo	VERB
aiua-13635	217	2	open	open	ADJ
aiua-13635	217	3	.	.	PUNCT
aiua-13635	218	1	2022	2022	NUM
aiua-13635	218	2	;	;	PUNCT
aiua-13635	218	3	7:100459	7:100459	NUM
aiua-13635	218	4	.	.	NOUN
aiua-13635	218	5	39	39	NUM
aiua-13635	218	6	.	.	PUNCT
aiua-13635	219	1	loeb	loeb	PROPN
aiua-13635	219	2	s	s	PROPN
aiua-13635	219	3	,	,	PUNCT
aiua-13635	219	4	byrne	byrne	ADJ
aiua-13635	219	5	n	n	CCONJ
aiua-13635	219	6	,	,	PUNCT
aiua-13635	219	7	walter	walter	PROPN
aiua-13635	219	8	d	d	PROPN
aiua-13635	219	9	,	,	PUNCT
aiua-13635	219	10	et	et	PROPN
aiua-13635	219	11	al	al	PROPN
aiua-13635	219	12	.	.	PROPN
aiua-13635	219	13	knowledge	knowledge	NOUN
aiua-13635	219	14	and	and	CCONJ
aiua-13635	219	15	practice	practice	NOUN
aiua-13635	219	16	regarding	regard	VERB
aiua-13635	219	17	prostate	prostate	NOUN
aiua-13635	219	18	cancer	cancer	NOUN
aiua-13635	219	19	germline	germline	NOUN
aiua-13635	219	20	testing	testing	NOUN
aiua-13635	219	21	among	among	ADP
aiua-13635	219	22	urologists	urologist	NOUN
aiua-13635	219	23	:	:	PUNCT
aiua-13635	219	24	gaps	gap	NOUN
aiua-13635	219	25	to	to	PART
aiua-13635	219	26	address	address	VERB
aiua-13635	219	27	for	for	ADP
aiua-13635	219	28	optimal	optimal	ADJ
aiua-13635	219	29	implementation	implementation	NOUN
aiua-13635	219	30	.	.	PUNCT
aiua-13635	220	1	cancer	cancer	NOUN
aiua-13635	220	2	treat	treat	VERB
aiua-13635	220	3	res	re	NOUN
aiua-13635	220	4	commun	commun	PROPN
aiua-13635	220	5	.	.	PUNCT
aiua-13635	221	1	2020	2020	NUM
aiua-13635	221	2	;	;	PUNCT
aiua-13635	221	3	25:100212	25:100212	X
aiua-13635	221	4	.	.	X
aiua-13635	221	5	correspondence	correspondence	NOUN
aiua-13635	221	6	simona	simona	PROPN
aiua-13635	221	7	vatrano	vatrano	PROPN
aiua-13635	221	8	simona.vatrano@gmail.com	simona.vatrano@gmail.com	PROPN
aiua-13635	222	1	cristina	cristina	PROPN
aiua-13635	222	2	alario	alario	PROPN
aiua-13635	222	3	alessia	alessia	PROPN
aiua-13635	222	4	chiarandà	chiarandà	VERB
aiua-13635	222	5	chiara	chiara	PROPN
aiua-13635	222	6	taranto	taranto	PROPN
aiua-13635	222	7	filippo	filippo	PROPN
aiua-13635	222	8	fraggetta	fraggetta	PROPN
aiua-13635	222	9	filippofra@hotmail.com	filippofra@hotmail.com	X
aiua-13635	222	10	pathology	pathology	PROPN
aiua-13635	222	11	unit	unit	NOUN
aiua-13635	222	12	-	-	PUNCT
aiua-13635	222	13	gravina	gravina	NOUN
aiua-13635	222	14	hospital	hospital	NOUN
aiua-13635	222	15	,	,	PUNCT
aiua-13635	222	16	caltagirone	caltagirone	NOUN
aiua-13635	222	17	(	(	PUNCT
aiua-13635	222	18	italy	italy	PROPN
aiua-13635	222	19	)	)	PUNCT
aiua-13635	222	20	pietro	pietro	PROPN
aiua-13635	222	21	pepe	pepe	PROPN
aiua-13635	222	22	(	(	PUNCT
aiua-13635	222	23	corresponding	corresponding	ADJ
aiua-13635	222	24	author	author	NOUN
aiua-13635	222	25	)	)	PUNCT
aiua-13635	223	1	piepepe@hotmail.com	piepepe@hotmail.com	X
aiua-13635	224	1	ludovica	ludovica	PROPN
aiua-13635	224	2	pepe	pepe	PROPN
aiua-13635	224	3	ludopepe97@gmail.com	ludopepe97@gmail.com	PROPN
aiua-13635	224	4	urology	urology	NOUN
aiua-13635	224	5	unit	unit	NOUN
aiua-13635	224	6	-	-	PUNCT
aiua-13635	224	7	cannizzaro	cannizzaro	NOUN
aiua-13635	224	8	hospital	hospital	NOUN
aiua-13635	224	9	,	,	PUNCT
aiua-13635	224	10	via	via	ADP
aiua-13635	224	11	messina	messina	PROPN
aiua-13635	224	12	829	829	NUM
aiua-13635	224	13	,	,	PUNCT
aiua-13635	224	14	catania	catania	PROPN
aiua-13635	224	15	(	(	PUNCT
aiua-13635	224	16	italy	italy	PROPN
aiua-13635	224	17	)	)	PUNCT
aiua-13635	224	18	nuccia	nuccia	PROPN
aiua-13635	224	19	vella	vella	PROPN
aiua-13635	224	20	genetic	genetic	ADJ
aiua-13635	224	21	unit	unit	NOUN
aiua-13635	224	22	-	-	PUNCT
aiua-13635	224	23	vittorio	vittorio	PROPN
aiua-13635	224	24	emanuele	emanuele	PROPN
aiua-13635	224	25	hospital	hospital	PROPN
aiua-13635	224	26	,	,	PUNCT
aiua-13635	224	27	gela	gela	PROPN
aiua-13635	224	28	(	(	PUNCT
aiua-13635	224	29	italy	italy	PROPN
aiua-13635	224	30	)	)	PUNCT
aiua-13635	224	31	renato	renato	PROPN
aiua-13635	224	32	scillieri	scillieri	PROPN
aiua-13635	224	33	cristina	cristina	PROPN
aiua-13635	224	34	mauceri	mauceri	PROPN
aiua-13635	224	35	oncologic	oncologic	PROPN
aiua-13635	224	36	screening	screen	VERB
aiua-13635	224	37	unit	unit	NOUN
aiua-13635	224	38	-	-	PUNCT
aiua-13635	224	39	catania	catania	PROPN
aiua-13635	224	40	,	,	PUNCT
aiua-13635	224	41	(	(	PUNCT
aiua-13635	224	42	italy	italy	PROPN
aiua-13635	224	43	)	)	PUNCT