id	sid	tid	token	lemma	pos
aiua-5759	1	1	stesura	stesura	PROPN
aiua-5759	1	2	seveso	seveso	PROPN
aiua-5759	1	3	archivio	archivio	PROPN
aiua-5759	1	4	italiano	italiano	X
aiua-5759	1	5	di	di	X
aiua-5759	1	6	urologia	urologia	PROPN
aiua-5759	1	7	e	e	PROPN
aiua-5759	1	8	andrologia	andrologia	NOUN
aiua-5759	1	9	2016	2016	NUM
aiua-5759	1	10	;	;	PUNCT
aiua-5759	1	11	88	88	NUM
aiua-5759	1	12	,	,	PUNCT
aiua-5759	1	13	172	172	NUM
aiua-5759	1	14	letter	letter	NOUN
aiua-5759	1	15	to	to	ADP
aiua-5759	1	16	editors	editor	NOUN
aiua-5759	1	17	about	about	ADP
aiua-5759	1	18	:	:	PUNCT
aiua-5759	1	19	clarification	clarification	NOUN
aiua-5759	1	20	to	to	PART
aiua-5759	1	21	provide	provide	VERB
aiua-5759	1	22	further	further	ADJ
aiua-5759	1	23	understanding	understanding	NOUN
aiua-5759	1	24	of	of	ADP
aiua-5759	1	25	the	the	DET
aiua-5759	1	26	conduct	conduct	NOUN
aiua-5759	1	27	and	and	CCONJ
aiua-5759	1	28	design	design	NOUN
aiua-5759	1	29	of	of	ADP
aiua-5759	1	30	tropic	tropic	NOUN
aiua-5759	1	31	:	:	PUNCT
aiua-5759	1	32	a	a	DET
aiua-5759	1	33	phase	phase	NOUN
aiua-5759	1	34	3	3	NUM
aiua-5759	1	35	trial	trial	NOUN
aiua-5759	1	36	of	of	ADP
aiua-5759	1	37	cabazitaxel	cabazitaxel	PROPN
aiua-5759	1	38	versus	versus	ADP
aiua-5759	1	39	mitoxantrone	mitoxantrone	NOUN
aiua-5759	1	40	in	in	ADP
aiua-5759	1	41	patients	patient	NOUN
aiua-5759	1	42	with	with	ADP
aiua-5759	1	43	metastatic	metastatic	ADJ
aiua-5759	1	44	castration	castration	NOUN
aiua-5759	1	45	-	-	PUNCT
aiua-5759	1	46	resistant	resistant	ADJ
aiua-5759	1	47	prostate	prostate	NOUN
aiua-5759	1	48	cancer	cancer	NOUN
aiua-5759	1	49	no	no	DET
aiua-5759	1	50	conflict	conflict	NOUN
aiua-5759	1	51	of	of	ADP
aiua-5759	1	52	interest	interest	NOUN
aiua-5759	1	53	declared	declare	VERB
aiua-5759	1	54	.	.	PUNCT
aiua-5759	2	1	doi	doi	NOUN
aiua-5759	2	2	:	:	PUNCT
aiua-5759	2	3	10.4081	10.4081	NUM
aiua-5759	2	4	/	/	SYM
aiua-5759	2	5	aiua.2016.1.72	aiua.2016.1.72	NOUN
aiua-5759	2	6	dear	dear	ADJ
aiua-5759	2	7	editors	editor	NOUN
aiua-5759	2	8	,	,	PUNCT
aiua-5759	2	9	we	we	PRON
aiua-5759	2	10	read	read	VERB
aiua-5759	2	11	with	with	ADP
aiua-5759	2	12	interest	interest	NOUN
aiua-5759	2	13	the	the	DET
aiua-5759	2	14	article	article	NOUN
aiua-5759	2	15	“	"	PUNCT
aiua-5759	2	16	efficacy	efficacy	NOUN
aiua-5759	2	17	and	and	CCONJ
aiua-5759	2	18	safety	safety	NOUN
aiua-5759	2	19	of	of	ADP
aiua-5759	2	20	second	second	ADJ
aiua-5759	2	21	-	-	PUNCT
aiua-5759	2	22	line	line	NOUN
aiua-5759	2	23	agents	agent	NOUN
aiua-5759	2	24	for	for	ADP
aiua-5759	2	25	treatment	treatment	NOUN
aiua-5759	2	26	of	of	ADP
aiua-5759	2	27	metastatic	metastatic	ADJ
aiua-5759	2	28	castration	castration	NOUN
aiua-5759	2	29	-	-	PUNCT
aiua-5759	2	30	resistant	resistant	ADJ
aiua-5759	2	31	prostate	prostate	NOUN
aiua-5759	2	32	cancer	cancer	NOUN
aiua-5759	2	33	progressing	progressing	NOUN
aiua-5759	2	34	after	after	ADP
aiua-5759	2	35	docetaxel	docetaxel	NOUN
aiua-5759	2	36	.	.	PUNCT
aiua-5759	3	1	a	a	DET
aiua-5759	3	2	systematic	systematic	ADJ
aiua-5759	3	3	review	review	NOUN
aiua-5759	3	4	and	and	CCONJ
aiua-5759	3	5	meta	meta	ADJ
aiua-5759	3	6	-	-	PUNCT
aiua-5759	3	7	analysis	analysis	NOUN
aiua-5759	3	8	”	"	PUNCT
aiua-5759	3	9	by	by	ADP
aiua-5759	3	10	perletti	perletti	PROPN
aiua-5759	3	11	et	et	PROPN
aiua-5759	3	12	al	al	PROPN
aiua-5759	3	13	.	.	PROPN
aiua-5759	4	1	in	in	ADP
aiua-5759	4	2	your	your	PRON
aiua-5759	4	3	journal	journal	NOUN
aiua-5759	4	4	(	(	PUNCT
aiua-5759	4	5	arch	arch	ADJ
aiua-5759	4	6	ital	ital	PROPN
aiua-5759	4	7	urol	urol	PROPN
aiua-5759	4	8	androl	androl	PROPN
aiua-5759	4	9	.	.	PROPN
aiua-5759	4	10	2015	2015	NUM
aiua-5759	4	11	;	;	PUNCT
aiua-5759	4	12	87:121	87:121	NUM
aiua-5759	4	13	-	-	SYM
aiua-5759	4	14	9	9	NUM
aiua-5759	4	15	)	)	PUNCT
aiua-5759	4	16	,	,	PUNCT
aiua-5759	4	17	which	which	PRON
aiua-5759	4	18	describes	describe	VERB
aiua-5759	4	19	the	the	DET
aiua-5759	4	20	results	result	NOUN
aiua-5759	4	21	of	of	ADP
aiua-5759	4	22	a	a	DET
aiua-5759	4	23	systematic	systematic	ADJ
aiua-5759	4	24	literature	literature	NOUN
aiua-5759	4	25	review	review	NOUN
aiua-5759	4	26	assessing	assess	VERB
aiua-5759	4	27	second	second	ADJ
aiua-5759	4	28	-	-	PUNCT
aiua-5759	4	29	line	line	NOUN
aiua-5759	4	30	agents	agent	NOUN
aiua-5759	4	31	used	use	VERB
aiua-5759	4	32	in	in	ADP
aiua-5759	4	33	the	the	DET
aiua-5759	4	34	treatment	treatment	NOUN
aiua-5759	4	35	of	of	ADP
aiua-5759	4	36	metastatic	metastatic	ADJ
aiua-5759	4	37	castration	castration	NOUN
aiua-5759	4	38	-	-	PUNCT
aiua-5759	4	39	resistant	resistant	ADJ
aiua-5759	4	40	prostate	prostate	NOUN
aiua-5759	4	41	cancer	cancer	NOUN
aiua-5759	4	42	(	(	PUNCT
aiua-5759	4	43	mcrpc	mcrpc	NOUN
aiua-5759	4	44	)	)	PUNCT
aiua-5759	4	45	progressing	progress	VERB
aiua-5759	4	46	after	after	ADP
aiua-5759	4	47	docetaxel	docetaxel	NOUN
aiua-5759	4	48	-	-	PUNCT
aiua-5759	4	49	based	base	VERB
aiua-5759	4	50	regimens	regimen	NOUN
aiua-5759	4	51	.	.	PUNCT
aiua-5759	5	1	the	the	DET
aiua-5759	5	2	authors	author	NOUN
aiua-5759	5	3	analyzed	analyze	VERB
aiua-5759	5	4	ten	ten	NUM
aiua-5759	5	5	articles	article	NOUN
aiua-5759	5	6	reporting	report	VERB
aiua-5759	5	7	the	the	DET
aiua-5759	5	8	results	result	NOUN
aiua-5759	5	9	of	of	ADP
aiua-5759	5	10	five	five	NUM
aiua-5759	5	11	phase	phase	NOUN
aiua-5759	5	12	3	3	NUM
aiua-5759	5	13	,	,	PUNCT
aiua-5759	5	14	randomized	randomize	VERB
aiua-5759	5	15	,	,	PUNCT
aiua-5759	5	16	controlled	control	VERB
aiua-5759	5	17	trials	trial	NOUN
aiua-5759	5	18	that	that	PRON
aiua-5759	5	19	enrolled	enrol	VERB
aiua-5759	5	20	patients	patient	NOUN
aiua-5759	5	21	with	with	ADP
aiua-5759	5	22	mcrpc	mcrpc	NOUN
aiua-5759	5	23	progressing	progress	VERB
aiua-5759	5	24	during	during	ADP
aiua-5759	5	25	or	or	CCONJ
aiua-5759	5	26	after	after	ADP
aiua-5759	5	27	first	first	ADJ
aiua-5759	5	28	-	-	PUNCT
aiua-5759	5	29	line	line	NOUN
aiua-5759	5	30	docetaxel	docetaxel	NOUN
aiua-5759	5	31	treatment	treatment	NOUN
aiua-5759	5	32	.	.	PUNCT
aiua-5759	6	1	this	this	PRON
aiua-5759	6	2	included	include	VERB
aiua-5759	6	3	the	the	DET
aiua-5759	6	4	phase	phase	NOUN
aiua-5759	6	5	3	3	NUM
aiua-5759	6	6	tropic	tropic	NOUN
aiua-5759	6	7	trial	trial	NOUN
aiua-5759	6	8	of	of	ADP
aiua-5759	6	9	cabazitaxel	cabazitaxel	PROPN
aiua-5759	6	10	versus	versus	ADP
aiua-5759	6	11	mitoxantrone	mitoxantrone	NOUN
aiua-5759	6	12	(	(	PUNCT
aiua-5759	6	13	1	1	NUM
aiua-5759	6	14	)	)	PUNCT
aiua-5759	6	15	,	,	PUNCT
aiua-5759	6	16	which	which	PRON
aiua-5759	6	17	provided	provide	VERB
aiua-5759	6	18	the	the	DET
aiua-5759	6	19	basis	basis	NOUN
aiua-5759	6	20	for	for	ADP
aiua-5759	6	21	the	the	DET
aiua-5759	6	22	regulatory	regulatory	ADJ
aiua-5759	6	23	approval	approval	NOUN
aiua-5759	6	24	of	of	ADP
aiua-5759	6	25	cabazitaxel	cabazitaxel	PROPN
aiua-5759	6	26	in	in	ADP
aiua-5759	6	27	this	this	DET
aiua-5759	6	28	setting	setting	NOUN
aiua-5759	6	29	.	.	PUNCT
aiua-5759	7	1	the	the	DET
aiua-5759	7	2	authors	author	NOUN
aiua-5759	7	3	conducted	conduct	VERB
aiua-5759	7	4	a	a	DET
aiua-5759	7	5	risk	risk	NOUN
aiua-5759	7	6	of	of	ADP
aiua-5759	7	7	bias	bias	NOUN
aiua-5759	7	8	analysis	analysis	NOUN
aiua-5759	7	9	for	for	ADP
aiua-5759	7	10	each	each	DET
aiua-5759	7	11	trial	trial	NOUN
aiua-5759	7	12	included	include	VERB
aiua-5759	7	13	in	in	ADP
aiua-5759	7	14	their	their	PRON
aiua-5759	7	15	review	review	NOUN
aiua-5759	7	16	and	and	CCONJ
aiua-5759	7	17	concluded	conclude	VERB
aiua-5759	7	18	that	that	SCONJ
aiua-5759	7	19	the	the	DET
aiua-5759	7	20	tropic	tropic	NOUN
aiua-5759	7	21	trial	trial	NOUN
aiua-5759	7	22	had	have	VERB
aiua-5759	7	23	a	a	DET
aiua-5759	7	24	high	high	ADJ
aiua-5759	7	25	risk	risk	NOUN
aiua-5759	7	26	of	of	ADP
aiua-5759	7	27	selection	selection	NOUN
aiua-5759	7	28	and	and	CCONJ
aiua-5759	7	29	performance	performance	NOUN
aiua-5759	7	30	/	/	SYM
aiua-5759	7	31	detection	detection	NOUN
aiua-5759	7	32	bias	bias	NOUN
aiua-5759	7	33	.	.	PUNCT
aiua-5759	8	1	however	however	ADV
aiua-5759	8	2	,	,	PUNCT
aiua-5759	8	3	in	in	ADP
aiua-5759	8	4	table	table	NOUN
aiua-5759	8	5	2	2	NUM
aiua-5759	8	6	,	,	PUNCT
aiua-5759	8	7	the	the	DET
aiua-5759	8	8	authors	author	NOUN
aiua-5759	8	9	made	make	VERB
aiua-5759	8	10	several	several	ADJ
aiua-5759	8	11	assumptions	assumption	NOUN
aiua-5759	8	12	about	about	ADP
aiua-5759	8	13	the	the	DET
aiua-5759	8	14	methodology	methodology	NOUN
aiua-5759	8	15	of	of	ADP
aiua-5759	8	16	the	the	DET
aiua-5759	8	17	tropic	tropic	NOUN
aiua-5759	8	18	trial	trial	NOUN
aiua-5759	8	19	,	,	PUNCT
aiua-5759	8	20	which	which	PRON
aiua-5759	8	21	we	we	PRON
aiua-5759	8	22	feel	feel	VERB
aiua-5759	8	23	warrant	warrant	ADJ
aiua-5759	8	24	clarification	clarification	NOUN
aiua-5759	8	25	.	.	PUNCT
aiua-5759	9	1	perletti	perletti	ADJ
aiua-5759	9	2	article	article	NOUN
aiua-5759	9	3	assumption	assumption	NOUN
aiua-5759	9	4	(	(	PUNCT
aiua-5759	9	5	row	row	NOUN
aiua-5759	9	6	1	1	NUM
aiua-5759	9	7	):	):	PUNCT
aiua-5759	9	8	risk	risk	NOUN
aiua-5759	9	9	of	of	ADP
aiua-5759	9	10	bias	bias	NOUN
aiua-5759	9	11	for	for	ADP
aiua-5759	9	12	the	the	DET
aiua-5759	9	13	random	random	ADJ
aiua-5759	9	14	sequence	sequence	NOUN
aiua-5759	9	15	generation	generation	NOUN
aiua-5759	9	16	used	use	VERB
aiua-5759	9	17	in	in	ADP
aiua-5759	9	18	the	the	DET
aiua-5759	9	19	tropic	tropic	NOUN
aiua-5759	9	20	study	study	NOUN
aiua-5759	9	21	was	be	AUX
aiua-5759	9	22	unclear	unclear	ADJ
aiua-5759	9	23	.	.	PUNCT
aiua-5759	10	1	the	the	DET
aiua-5759	10	2	dynamic	dynamic	ADJ
aiua-5759	10	3	allocation	allocation	NOUN
aiua-5759	10	4	system	system	NOUN
aiua-5759	10	5	was	be	AUX
aiua-5759	10	6	not	not	PART
aiua-5759	10	7	a	a	DET
aiua-5759	10	8	random	random	ADJ
aiua-5759	10	9	sampling	sampling	NOUN
aiua-5759	10	10	strategy	strategy	NOUN
aiua-5759	10	11	in	in	ADP
aiua-5759	10	12	a	a	DET
aiua-5759	10	13	strict	strict	ADJ
aiua-5759	10	14	sense	sense	NOUN
aiua-5759	10	15	and	and	CCONJ
aiua-5759	10	16	patients	patient	NOUN
aiua-5759	10	17	were	be	AUX
aiua-5759	10	18	not	not	PART
aiua-5759	10	19	allocated	allocate	VERB
aiua-5759	10	20	randomly	randomly	ADV
aiua-5759	10	21	because	because	SCONJ
aiua-5759	10	22	allocation	allocation	NOUN
aiua-5759	10	23	was	be	AUX
aiua-5759	10	24	determined	determine	VERB
aiua-5759	10	25	on	on	ADP
aiua-5759	10	26	the	the	DET
aiua-5759	10	27	basis	basis	NOUN
aiua-5759	10	28	of	of	ADP
aiua-5759	10	29	prognostic	prognostic	ADJ
aiua-5759	10	30	factors	factor	NOUN
aiua-5759	10	31	chosen	choose	VERB
aiua-5759	10	32	as	as	ADP
aiua-5759	10	33	inclusion	inclusion	NOUN
aiua-5759	10	34	criteria	criterion	NOUN
aiua-5759	10	35	.	.	PUNCT
aiua-5759	11	1	author	author	NOUN
aiua-5759	11	2	correction	correction	NOUN
aiua-5759	11	3	:	:	PUNCT
aiua-5759	11	4	random	random	ADJ
aiua-5759	11	5	sequence	sequence	NOUN
aiua-5759	11	6	generation	generation	NOUN
aiua-5759	11	7	for	for	ADP
aiua-5759	11	8	the	the	DET
aiua-5759	11	9	tropic	tropic	NOUN
aiua-5759	11	10	study	study	NOUN
aiua-5759	11	11	was	be	AUX
aiua-5759	11	12	undertaken	undertake	VERB
aiua-5759	11	13	using	use	VERB
aiua-5759	11	14	stratified	stratified	ADJ
aiua-5759	11	15	randomization	randomization	NOUN
aiua-5759	11	16	by	by	ADP
aiua-5759	11	17	means	mean	NOUN
aiua-5759	11	18	of	of	ADP
aiua-5759	11	19	an	an	DET
aiua-5759	11	20	interactive	interactive	ADJ
aiua-5759	11	21	voice	voice	NOUN
aiua-5759	11	22	response	response	NOUN
aiua-5759	11	23	system	system	NOUN
aiua-5759	11	24	(	(	PUNCT
aiua-5759	11	25	ivrs	ivrs	PROPN
aiua-5759	11	26	)	)	PUNCT
aiua-5759	11	27	.	.	PUNCT
aiua-5759	12	1	stratification	stratification	NOUN
aiua-5759	12	2	used	use	VERB
aiua-5759	12	3	two	two	NUM
aiua-5759	12	4	baseline	baseline	ADJ
aiua-5759	12	5	factors	factor	NOUN
aiua-5759	12	6	(	(	PUNCT
aiua-5759	12	7	disease	disease	NOUN
aiua-5759	12	8	measurability	measurability	NOUN
aiua-5759	12	9	and	and	CCONJ
aiua-5759	12	10	performance	performance	NOUN
aiua-5759	12	11	status	status	NOUN
aiua-5759	12	12	)	)	PUNCT
aiua-5759	12	13	(	(	PUNCT
aiua-5759	12	14	1	1	NUM
aiua-5759	12	15	)	)	PUNCT
aiua-5759	12	16	.	.	PUNCT
aiua-5759	13	1	a	a	DET
aiua-5759	13	2	dynamic	dynamic	ADJ
aiua-5759	13	3	allocation	allocation	NOUN
aiua-5759	13	4	was	be	AUX
aiua-5759	13	5	rarely	rarely	ADV
aiua-5759	13	6	instigated	instigate	VERB
aiua-5759	13	7	and	and	CCONJ
aiua-5759	13	8	was	be	AUX
aiua-5759	13	9	imposed	impose	VERB
aiua-5759	13	10	only	only	ADV
aiua-5759	13	11	if	if	SCONJ
aiua-5759	13	12	there	there	PRON
aiua-5759	13	13	was	be	VERB
aiua-5759	13	14	an	an	DET
aiua-5759	13	15	extreme	extreme	ADJ
aiua-5759	13	16	assignment	assignment	NOUN
aiua-5759	13	17	imbalance	imbalance	NOUN
aiua-5759	13	18	in	in	ADP
aiua-5759	13	19	a	a	DET
aiua-5759	13	20	center	center	NOUN
aiua-5759	13	21	.	.	PUNCT
aiua-5759	14	1	perletti	perletti	ADJ
aiua-5759	14	2	article	article	NOUN
aiua-5759	14	3	assumption	assumption	NOUN
aiua-5759	14	4	(	(	PUNCT
aiua-5759	14	5	row	row	NOUN
aiua-5759	14	6	2	2	NUM
aiua-5759	14	7	):	):	PUNCT
aiua-5759	14	8	risk	risk	NOUN
aiua-5759	14	9	of	of	ADP
aiua-5759	14	10	bias	bias	NOUN
aiua-5759	14	11	for	for	ADP
aiua-5759	14	12	concealment	concealment	NOUN
aiua-5759	14	13	of	of	ADP
aiua-5759	14	14	treatment	treatment	NOUN
aiua-5759	14	15	allocation	allocation	NOUN
aiua-5759	14	16	in	in	ADP
aiua-5759	14	17	tropic	tropic	NOUN
aiua-5759	14	18	was	be	AUX
aiua-5759	14	19	high	high	ADJ
aiua-5759	14	20	.	.	PUNCT
aiua-5759	15	1	patients	patient	NOUN
aiua-5759	15	2	and	and	CCONJ
aiua-5759	15	3	treating	treat	VERB
aiua-5759	15	4	physicians	physician	NOUN
aiua-5759	15	5	were	be	AUX
aiua-5759	15	6	not	not	PART
aiua-5759	15	7	masked	mask	VERB
aiua-5759	15	8	to	to	ADP
aiua-5759	15	9	treatment	treatment	NOUN
aiua-5759	15	10	allocation	allocation	NOUN
aiua-5759	15	11	.	.	PUNCT
aiua-5759	16	1	author	author	NOUN
aiua-5759	16	2	correction	correction	NOUN
aiua-5759	16	3	:	:	PUNCT
aiua-5759	16	4	although	although	SCONJ
aiua-5759	16	5	individual	individual	ADJ
aiua-5759	16	6	patients	patient	NOUN
aiua-5759	16	7	at	at	ADP
aiua-5759	16	8	individual	individual	ADJ
aiua-5759	16	9	sites	site	NOUN
aiua-5759	16	10	were	be	AUX
aiua-5759	16	11	not	not	PART
aiua-5759	16	12	blinded	blind	VERB
aiua-5759	16	13	,	,	PUNCT
aiua-5759	16	14	a	a	DET
aiua-5759	16	15	centralized	centralized	ADJ
aiua-5759	16	16	ivrs	ivrs	NOUN
aiua-5759	16	17	was	be	AUX
aiua-5759	16	18	used	use	VERB
aiua-5759	16	19	in	in	ADP
aiua-5759	16	20	tropic	tropic	NOUN
aiua-5759	16	21	,	,	PUNCT
aiua-5759	16	22	therefore	therefore	ADV
aiua-5759	16	23	patients	patient	NOUN
aiua-5759	16	24	and	and	CCONJ
aiua-5759	16	25	treating	treat	VERB
aiua-5759	16	26	physicians	physician	NOUN
aiua-5759	16	27	were	be	AUX
aiua-5759	16	28	not	not	PART
aiua-5759	16	29	aware	aware	ADJ
aiua-5759	16	30	of	of	ADP
aiua-5759	16	31	global	global	ADJ
aiua-5759	16	32	enrollment	enrollment	NOUN
aiua-5759	16	33	information	information	NOUN
aiua-5759	16	34	or	or	CCONJ
aiua-5759	16	35	the	the	DET
aiua-5759	16	36	treatment	treatment	NOUN
aiua-5759	16	37	allocation	allocation	NOUN
aiua-5759	16	38	at	at	ADP
aiua-5759	16	39	other	other	ADJ
aiua-5759	16	40	sites	site	NOUN
aiua-5759	16	41	.	.	PUNCT
aiua-5759	17	1	perletti	perletti	ADJ
aiua-5759	17	2	article	article	NOUN
aiua-5759	17	3	assumption	assumption	NOUN
aiua-5759	17	4	(	(	PUNCT
aiua-5759	17	5	row	row	NOUN
aiua-5759	17	6	3	3	NUM
aiua-5759	17	7	):	):	PUNCT
aiua-5759	17	8	risk	risk	NOUN
aiua-5759	17	9	of	of	ADP
aiua-5759	17	10	bias	bias	NOUN
aiua-5759	17	11	for	for	ADP
aiua-5759	17	12	the	the	DET
aiua-5759	17	13	blinding	blinding	NOUN
aiua-5759	17	14	of	of	ADP
aiua-5759	17	15	patients	patient	NOUN
aiua-5759	17	16	and	and	CCONJ
aiua-5759	17	17	personnel	personnel	NOUN
aiua-5759	17	18	in	in	ADP
aiua-5759	17	19	tropic	tropic	NOUN
aiua-5759	17	20	was	be	AUX
aiua-5759	17	21	high	high	ADJ
aiua-5759	17	22	.	.	PUNCT
aiua-5759	18	1	the	the	DET
aiua-5759	18	2	study	study	NOUN
aiua-5759	18	3	had	have	VERB
aiua-5759	18	4	an	an	DET
aiua-5759	18	5	open	open	ADJ
aiua-5759	18	6	-	-	PUNCT
aiua-5759	18	7	label	label	NOUN
aiua-5759	18	8	design	design	NOUN
aiua-5759	18	9	.	.	PUNCT
aiua-5759	19	1	although	although	SCONJ
aiua-5759	19	2	survival	survival	NOUN
aiua-5759	19	3	,	,	PUNCT
aiua-5759	19	4	biochemical	biochemical	ADJ
aiua-5759	19	5	findings	finding	NOUN
aiua-5759	19	6	and	and	CCONJ
aiua-5759	19	7	radiographic	radiographic	ADJ
aiua-5759	19	8	evidence	evidence	NOUN
aiua-5759	19	9	could	could	AUX
aiua-5759	19	10	not	not	PART
aiua-5759	19	11	have	have	AUX
aiua-5759	19	12	been	be	AUX
aiua-5759	19	13	influenced	influence	VERB
aiua-5759	19	14	by	by	ADP
aiua-5759	19	15	the	the	DET
aiua-5759	19	16	open	open	ADJ
aiua-5759	19	17	-	-	PUNCT
aiua-5759	19	18	label	label	NOUN
aiua-5759	19	19	setting	setting	NOUN
aiua-5759	19	20	,	,	PUNCT
aiua-5759	19	21	other	other	ADJ
aiua-5759	19	22	endpoints	endpoint	NOUN
aiua-5759	19	23	(	(	PUNCT
aiua-5759	19	24	e.g.	e.g.	ADV
aiua-5759	19	25	,	,	PUNCT
aiua-5759	19	26	pain	pain	NOUN
aiua-5759	19	27	,	,	PUNCT
aiua-5759	19	28	quality	quality	NOUN
aiua-5759	19	29	of	of	ADP
aiua-5759	19	30	life	life	NOUN
aiua-5759	19	31	)	)	PUNCT
aiua-5759	19	32	could	could	AUX
aiua-5759	19	33	have	have	AUX
aiua-5759	19	34	been	be	AUX
aiua-5759	19	35	prone	prone	ADJ
aiua-5759	19	36	to	to	ADP
aiua-5759	19	37	performance	performance	NOUN
aiua-5759	19	38	bias	bias	NOUN
aiua-5759	19	39	.	.	PUNCT
aiua-5759	20	1	author	author	NOUN
aiua-5759	20	2	correction	correction	NOUN
aiua-5759	20	3	:	:	PUNCT
aiua-5759	20	4	we	we	PRON
aiua-5759	20	5	agree	agree	VERB
aiua-5759	20	6	that	that	SCONJ
aiua-5759	20	7	efficacy	efficacy	NOUN
aiua-5759	20	8	endpoints	endpoint	NOUN
aiua-5759	20	9	(	(	PUNCT
aiua-5759	20	10	overall	overall	ADJ
aiua-5759	20	11	survival	survival	NOUN
aiua-5759	20	12	[	[	X
aiua-5759	20	13	os	os	X
aiua-5759	20	14	]	]	X
aiua-5759	20	15	,	,	PUNCT
aiua-5759	20	16	prostate	prostate	NOUN
aiua-5759	20	17	-	-	PUNCT
aiua-5759	20	18	specific	specific	ADJ
aiua-5759	20	19	antigen	antigen	NOUN
aiua-5759	20	20	[	[	X
aiua-5759	20	21	psa	psa	X
aiua-5759	20	22	]	]	PUNCT
aiua-5759	20	23	levels	level	NOUN
aiua-5759	20	24	,	,	PUNCT
aiua-5759	20	25	radiographic	radiographic	ADJ
aiua-5759	20	26	response	response	NOUN
aiua-5759	20	27	/	/	SYM
aiua-5759	20	28	progression	progression	NOUN
aiua-5759	20	29	)	)	PUNCT
aiua-5759	20	30	were	be	AUX
aiua-5759	20	31	not	not	PART
aiua-5759	20	32	impacted	impact	VERB
aiua-5759	20	33	by	by	ADP
aiua-5759	20	34	the	the	DET
aiua-5759	20	35	open	open	ADJ
aiua-5759	20	36	-	-	PUNCT
aiua-5759	20	37	label	label	NOUN
aiua-5759	20	38	study	study	NOUN
aiua-5759	20	39	design	design	NOUN
aiua-5759	20	40	or	or	CCONJ
aiua-5759	20	41	subject	subject	NOUN
aiua-5759	20	42	to	to	ADP
aiua-5759	20	43	bias	bias	NOUN
aiua-5759	20	44	.	.	PUNCT
aiua-5759	21	1	we	we	PRON
aiua-5759	21	2	note	note	VERB
aiua-5759	21	3	that	that	SCONJ
aiua-5759	21	4	quality	quality	NOUN
aiua-5759	21	5	of	of	ADP
aiua-5759	21	6	life	life	NOUN
aiua-5759	21	7	data	datum	NOUN
aiua-5759	21	8	were	be	AUX
aiua-5759	21	9	not	not	PART
aiua-5759	21	10	collected	collect	VERB
aiua-5759	21	11	.	.	PUNCT
aiua-5759	22	1	perletti	perletti	ADJ
aiua-5759	22	2	article	article	NOUN
aiua-5759	22	3	assumption	assumption	NOUN
aiua-5759	22	4	(	(	PUNCT
aiua-5759	22	5	row	row	NOUN
aiua-5759	22	6	5	5	NUM
aiua-5759	22	7	):	):	PUNCT
aiua-5759	22	8	risk	risk	NOUN
aiua-5759	22	9	of	of	ADP
aiua-5759	22	10	bias	bias	NOUN
aiua-5759	22	11	for	for	ADP
aiua-5759	22	12	any	any	DET
aiua-5759	22	13	incomplete	incomplete	ADJ
aiua-5759	22	14	outcome	outcome	NOUN
aiua-5759	22	15	data	datum	NOUN
aiua-5759	22	16	in	in	ADP
aiua-5759	22	17	the	the	DET
aiua-5759	22	18	tropic	tropic	NOUN
aiua-5759	22	19	trial	trial	NOUN
aiua-5759	22	20	was	be	AUX
aiua-5759	22	21	unclear	unclear	ADJ
aiua-5759	22	22	because	because	SCONJ
aiua-5759	22	23	no	no	DET
aiua-5759	22	24	detailed	detailed	ADJ
aiua-5759	22	25	information	information	NOUN
aiua-5759	22	26	about	about	ADP
aiua-5759	22	27	censoring	censor	VERB
aiua-5759	22	28	rules	rule	NOUN
aiua-5759	22	29	was	be	AUX
aiua-5759	22	30	provided	provide	VERB
aiua-5759	22	31	.	.	PUNCT
aiua-5759	23	1	author	author	NOUN
aiua-5759	23	2	correction	correction	NOUN
aiua-5759	23	3	:	:	PUNCT
aiua-5759	23	4	this	this	DET
aiua-5759	23	5	statement	statement	NOUN
aiua-5759	23	6	is	be	AUX
aiua-5759	23	7	puzzling	puzzle	VERB
aiua-5759	23	8	.	.	PUNCT
aiua-5759	24	1	the	the	DET
aiua-5759	24	2	primary	primary	ADJ
aiua-5759	24	3	endpoint	endpoint	NOUN
aiua-5759	24	4	of	of	ADP
aiua-5759	24	5	the	the	DET
aiua-5759	24	6	tropic	tropic	NOUN
aiua-5759	24	7	study	study	NOUN
aiua-5759	24	8	was	be	AUX
aiua-5759	24	9	os	os	NOUN
aiua-5759	24	10	.	.	PUNCT
aiua-5759	25	1	the	the	DET
aiua-5759	25	2	primary	primary	ADJ
aiua-5759	25	3	publication	publication	NOUN
aiua-5759	25	4	of	of	ADP
aiua-5759	25	5	tropic	tropic	NOUN
aiua-5759	25	6	data	datum	NOUN
aiua-5759	25	7	states	state	VERB
aiua-5759	25	8	that	that	SCONJ
aiua-5759	25	9	os	os	PROPN
aiua-5759	25	10	data	datum	NOUN
aiua-5759	25	11	were	be	AUX
aiua-5759	25	12	censored	censor	VERB
aiua-5759	25	13	at	at	ADP
aiua-5759	25	14	the	the	DET
aiua-5759	25	15	last	last	ADJ
aiua-5759	25	16	date	date	NOUN
aiua-5759	25	17	the	the	DET
aiua-5759	25	18	patient	patient	NOUN
aiua-5759	25	19	was	be	AUX
aiua-5759	25	20	known	know	VERB
aiua-5759	25	21	to	to	PART
aiua-5759	25	22	be	be	AUX
aiua-5759	25	23	alive	alive	ADJ
aiua-5759	25	24	or	or	CCONJ
aiua-5759	25	25	at	at	ADP
aiua-5759	25	26	the	the	DET
aiua-5759	25	27	analysis	analysis	NOUN
aiua-5759	25	28	cut	cut	VERB
aiua-5759	25	29	-	-	PUNCT
aiua-5759	25	30	off	off	ADP
aiua-5759	25	31	date	date	NOUN
aiua-5759	25	32	,	,	PUNCT
aiua-5759	25	33	whichever	whichever	PRON
aiua-5759	25	34	was	be	AUX
aiua-5759	25	35	earliest	early	ADJ
aiua-5759	25	36	(	(	PUNCT
aiua-5759	25	37	1	1	NUM
aiua-5759	25	38	)	)	PUNCT
aiua-5759	25	39	.	.	PUNCT
aiua-5759	26	1	almost	almost	ADV
aiua-5759	26	2	all	all	DET
aiua-5759	26	3	patients	patient	NOUN
aiua-5759	26	4	died	die	VERB
aiua-5759	26	5	before	before	ADP
aiua-5759	26	6	the	the	DET
aiua-5759	26	7	end	end	NOUN
aiua-5759	26	8	of	of	ADP
aiua-5759	26	9	the	the	DET
aiua-5759	26	10	study	study	NOUN
aiua-5759	26	11	or	or	CCONJ
aiua-5759	26	12	were	be	AUX
aiua-5759	26	13	censored	censor	VERB
aiua-5759	26	14	at	at	ADP
aiua-5759	26	15	the	the	DET
aiua-5759	26	16	study	study	NOUN
aiua-5759	26	17	cut	cut	VERB
aiua-5759	26	18	-	-	PUNCT
aiua-5759	26	19	off	off	ADP
aiua-5759	26	20	date	date	NOUN
aiua-5759	26	21	.	.	PUNCT
aiua-5759	27	1	os	os	PROPN
aiua-5759	27	2	data	datum	NOUN
aiua-5759	27	3	were	be	AUX
aiua-5759	27	4	missing	miss	VERB
aiua-5759	27	5	in	in	ADP
aiua-5759	27	6	very	very	ADV
aiua-5759	27	7	few	few	ADJ
aiua-5759	27	8	patients	patient	NOUN
aiua-5759	27	9	.	.	PUNCT
aiua-5759	28	1	perletti	perletti	ADJ
aiua-5759	28	2	article	article	NOUN
aiua-5759	28	3	assumption	assumption	NOUN
aiua-5759	28	4	(	(	PUNCT
aiua-5759	28	5	row	row	NOUN
aiua-5759	28	6	7	7	NUM
aiua-5759	28	7	):	):	PUNCT
aiua-5759	28	8	risk	risk	NOUN
aiua-5759	28	9	of	of	ADP
aiua-5759	28	10	bias	bias	NOUN
aiua-5759	28	11	for	for	ADP
aiua-5759	28	12	other	other	ADJ
aiua-5759	28	13	factors	factor	NOUN
aiua-5759	28	14	,	,	PUNCT
aiua-5759	28	15	such	such	ADJ
aiua-5759	28	16	as	as	ADP
aiua-5759	28	17	baseline	baseline	ADJ
aiua-5759	28	18	imbalances	imbalance	NOUN
aiua-5759	28	19	,	,	PUNCT
aiua-5759	28	20	was	be	AUX
aiua-5759	28	21	unclear	unclear	ADJ
aiua-5759	28	22	for	for	ADP
aiua-5759	28	23	tropic	tropic	NOUN
aiua-5759	28	24	.	.	PUNCT
aiua-5759	29	1	in	in	ADP
aiua-5759	29	2	a	a	DET
aiua-5759	29	3	long	long	ADJ
aiua-5759	29	4	-	-	PUNCT
aiua-5759	29	5	term	term	NOUN
aiua-5759	29	6	survival	survival	NOUN
aiua-5759	29	7	analysis	analysis	NOUN
aiua-5759	29	8	,	,	PUNCT
aiua-5759	29	9	it	it	PRON
aiua-5759	29	10	was	be	AUX
aiua-5759	29	11	shown	show	VERB
aiua-5759	29	12	that	that	SCONJ
aiua-5759	29	13	18	18	NUM
aiua-5759	29	14	%	%	NOUN
aiua-5759	29	15	and	and	CCONJ
aiua-5759	29	16	9	9	NUM
aiua-5759	29	17	%	%	NOUN
aiua-5759	29	18	of	of	ADP
aiua-5759	29	19	patients	patient	NOUN
aiua-5759	29	20	in	in	ADP
aiua-5759	29	21	the	the	DET
aiua-5759	29	22	cabazitaxel	cabazitaxel	PROPN
aiua-5759	29	23	and	and	CCONJ
aiua-5759	29	24	mitoxantrone	mitoxantrone	ADJ
aiua-5759	29	25	treatment	treatment	NOUN
aiua-5759	29	26	arms	arm	NOUN
aiua-5759	29	27	,	,	PUNCT
aiua-5759	29	28	respectively	respectively	ADV
aiua-5759	29	29	,	,	PUNCT
aiua-5759	29	30	were	be	AUX
aiua-5759	29	31	alive	alive	ADJ
aiua-5759	29	32	at	at	ADP
aiua-5759	29	33	24	24	NUM
aiua-5759	29	34	months	month	NOUN
aiua-5759	29	35	(	(	PUNCT
aiua-5759	29	36	2	2	NUM
aiua-5759	29	37	)	)	PUNCT
aiua-5759	29	38	.	.	PUNCT
aiua-5759	30	1	at	at	ADP
aiua-5759	30	2	baseline	baseline	NOUN
aiua-5759	30	3	,	,	PUNCT
aiua-5759	30	4	the	the	DET
aiua-5759	30	5	presence	presence	NOUN
aiua-5759	30	6	of	of	ADP
aiua-5759	30	7	visceral	visceral	ADJ
aiua-5759	30	8	metastases	metastasis	NOUN
aiua-5759	30	9	,	,	PUNCT
aiua-5759	30	10	which	which	PRON
aiua-5759	30	11	can	can	AUX
aiua-5759	30	12	be	be	AUX
aiua-5759	30	13	prognostic	prognostic	ADJ
aiua-5759	30	14	for	for	ADP
aiua-5759	30	15	os	os	NOUN
aiua-5759	30	16	,	,	PUNCT
aiua-5759	30	17	was	be	AUX
aiua-5759	30	18	higher	high	ADJ
aiua-5759	30	19	in	in	ADP
aiua-5759	30	20	the	the	DET
aiua-5759	30	21	mitoxantrone	mitoxantrone	ADJ
aiua-5759	30	22	arm	arm	NOUN
aiua-5759	30	23	(	(	PUNCT
aiua-5759	30	24	20	20	NUM
aiua-5759	30	25	%	%	NOUN
aiua-5759	30	26	)	)	PUNCT
aiua-5759	30	27	compared	compare	VERB
aiua-5759	30	28	with	with	ADP
aiua-5759	30	29	the	the	DET
aiua-5759	30	30	cabazitaxel	cabazitaxel	PROPN
aiua-5759	30	31	arm	arm	NOUN
aiua-5759	30	32	(	(	PUNCT
aiua-5759	30	33	15	15	NUM
aiua-5759	30	34	%	%	NOUN
aiua-5759	30	35	)	)	PUNCT
aiua-5759	30	36	.	.	PUNCT
aiua-5759	31	1	author	author	NOUN
aiua-5759	31	2	correction	correction	PROPN
aiua-5759	31	3	:	:	PUNCT
aiua-5759	31	4	data	datum	NOUN
aiua-5759	31	5	for	for	ADP
aiua-5759	31	6	baseline	baseline	ADJ
aiua-5759	31	7	visceral	visceral	ADJ
aiua-5759	31	8	metastases	metastasis	NOUN
aiua-5759	31	9	in	in	ADP
aiua-5759	31	10	tropic	tropic	NOUN
aiua-5759	31	11	are	be	AUX
aiua-5759	31	12	reported	report	VERB
aiua-5759	31	13	incorrectly	incorrectly	ADV
aiua-5759	31	14	by	by	ADP
aiua-5759	31	15	perletti	perletti	PROPN
aiua-5759	31	16	et	et	PROPN
aiua-5759	31	17	al	al	PROPN
aiua-5759	31	18	.	.	PROPN
aiua-5759	32	1	among	among	ADP
aiua-5759	32	2	patients	patient	NOUN
aiua-5759	32	3	receiving	receive	VERB
aiua-5759	32	4	cabazitaxel	cabazitaxel	NOUN
aiua-5759	32	5	(	(	PUNCT
aiua-5759	32	6	n	n	NOUN
aiua-5759	32	7	=	=	SYM
aiua-5759	32	8	378	378	NUM
aiua-5759	32	9	)	)	PUNCT
aiua-5759	32	10	and	and	CCONJ
aiua-5759	32	11	mitoxantrone	mitoxantrone	NOUN
aiua-5759	32	12	(	(	PUNCT
aiua-5759	32	13	n	n	NOUN
aiua-5759	32	14	=	=	SYM
aiua-5759	32	15	377	377	NUM
aiua-5759	32	16	)	)	PUNCT
aiua-5759	32	17	,	,	PUNCT
aiua-5759	32	18	25	25	NUM
aiua-5759	32	19	%	%	NOUN
aiua-5759	32	20	of	of	ADP
aiua-5759	32	21	patients	patient	NOUN
aiua-5759	32	22	in	in	ADP
aiua-5759	32	23	each	each	DET
aiua-5759	32	24	treatment	treatment	NOUN
aiua-5759	32	25	arm	arm	NOUN
aiua-5759	32	26	had	have	AUX
aiua-5759	32	27	baseline	baseline	VERB
aiua-5759	32	28	visceral	visceral	ADJ
aiua-5759	32	29	metastases	metastasis	NOUN
aiua-5759	32	30	(	(	PUNCT
aiua-5759	32	31	n	n	NOUN
aiua-5759	32	32	=	=	SYM
aiua-5759	32	33	94	94	NUM
aiua-5759	32	34	in	in	ADP
aiua-5759	32	35	each	each	DET
aiua-5759	32	36	arm	arm	NOUN
aiua-5759	32	37	)	)	PUNCT
aiua-5759	32	38	(	(	PUNCT
aiua-5759	32	39	1	1	NUM
aiua-5759	32	40	)	)	PUNCT
aiua-5759	32	41	,	,	PUNCT
aiua-5759	32	42	thus	thus	ADV
aiua-5759	32	43	no	no	DET
aiua-5759	32	44	imbalance	imbalance	NOUN
aiua-5759	32	45	exists	exist	VERB
aiua-5759	32	46	.	.	PUNCT
aiua-5759	33	1	after	after	ADP
aiua-5759	33	2	24	24	NUM
aiua-5759	33	3	months	month	NOUN
aiua-5759	33	4	,	,	PUNCT
aiua-5759	33	5	almost	almost	ADV
aiua-5759	33	6	twice	twice	DET
aiua-5759	33	7	as	as	ADV
aiua-5759	33	8	many	many	ADJ
aiua-5759	33	9	patients	patient	NOUN
aiua-5759	33	10	were	be	AUX
aiua-5759	33	11	alive	alive	ADJ
aiua-5759	33	12	in	in	ADP
aiua-5759	33	13	the	the	DET
aiua-5759	33	14	cabazitaxel	cabazitaxel	PROPN
aiua-5759	33	15	arm	arm	NOUN
aiua-5759	33	16	(	(	PUNCT
aiua-5759	33	17	n	n	NOUN
aiua-5759	33	18	=	=	SYM
aiua-5759	33	19	60	60	NUM
aiua-5759	33	20	,	,	PUNCT
aiua-5759	33	21	15.9	15.9	NUM
aiua-5759	33	22	%	%	NOUN
aiua-5759	33	23	)	)	PUNCT
aiua-5759	33	24	compared	compare	VERB
aiua-5759	33	25	with	with	ADP
aiua-5759	33	26	the	the	DET
aiua-5759	33	27	mitoxantrone	mitoxantrone	ADJ
aiua-5759	33	28	arm	arm	NOUN
aiua-5759	33	29	(	(	PUNCT
aiua-5759	33	30	n	n	NOUN
aiua-5759	33	31	=	=	SYM
aiua-5759	33	32	31	31	NUM
aiua-5759	33	33	,	,	PUNCT
aiua-5759	33	34	8.2	8.2	NUM
aiua-5759	33	35	%	%	NOUN
aiua-5759	33	36	)	)	PUNCT
aiua-5759	33	37	,	,	PUNCT
aiua-5759	33	38	demonstrating	demonstrate	VERB
aiua-5759	33	39	a	a	DET
aiua-5759	33	40	long	long	ADJ
aiua-5759	33	41	-	-	PUNCT
aiua-5759	33	42	term	term	NOUN
aiua-5759	33	43	os	os	NOUN
aiua-5759	33	44	benefit	benefit	NOUN
aiua-5759	33	45	for	for	ADP
aiua-5759	33	46	cabazitaxel	cabazitaxel	PROPN
aiua-5759	33	47	versus	versus	ADP
aiua-5759	33	48	mitoxantrone	mitoxantrone	NOUN
aiua-5759	33	49	(	(	PUNCT
aiua-5759	33	50	2	2	NUM
aiua-5759	33	51	)	)	PUNCT
aiua-5759	33	52	.	.	PUNCT
aiua-5759	34	1	in	in	ADP
aiua-5759	34	2	addition	addition	NOUN
aiua-5759	34	3	,	,	PUNCT
aiua-5759	34	4	a	a	DET
aiua-5759	34	5	multivariate	multivariate	NOUN
aiua-5759	34	6	analysis	analysis	NOUN
aiua-5759	34	7	supports	support	VERB
aiua-5759	34	8	the	the	DET
aiua-5759	34	9	os	os	ADJ
aiua-5759	34	10	benefit	benefit	NOUN
aiua-5759	34	11	of	of	ADP
aiua-5759	34	12	cabazitaxel	cabazitaxel	PROPN
aiua-5759	34	13	(	(	PUNCT
aiua-5759	34	14	2	2	NUM
aiua-5759	34	15	)	)	PUNCT
aiua-5759	34	16	.	.	PUNCT
aiua-5759	35	1	(	(	PUNCT
aiua-5759	35	2	remark	remark	NOUN
aiua-5759	35	3	1	1	NUM
aiua-5759	35	4	)	)	PUNCT
aiua-5759	35	5	perletti	perletti	NOUN
aiua-5759	35	6	et	et	NOUN
aiua-5759	35	7	al	al	PROPN
aiua-5759	35	8	.	.	PROPN
aiua-5759	36	1	also	also	ADV
aiua-5759	36	2	assessed	assess	VERB
aiua-5759	36	3	the	the	DET
aiua-5759	36	4	effects	effect	NOUN
aiua-5759	36	5	of	of	ADP
aiua-5759	36	6	the	the	DET
aiua-5759	36	7	interventions	intervention	NOUN
aiua-5759	36	8	in	in	ADP
aiua-5759	36	9	the	the	DET
aiua-5759	36	10	selected	select	VERB
aiua-5759	36	11	trials	trial	NOUN
aiua-5759	36	12	on	on	ADP
aiua-5759	36	13	os	os	NOUN
aiua-5759	36	14	and	and	CCONJ
aiua-5759	36	15	radiographic	radiographic	ADJ
aiua-5759	36	16	progression	progression	NOUN
aiua-5759	36	17	-	-	PUNCT
aiua-5759	36	18	free	free	ADJ
aiua-5759	36	19	de	de	X
aiua-5759	36	20	bono	bono	X
aiua-5759	36	21	letter_stesura	letter_stesura	NOUN
aiua-5759	36	22	seveso	seveso	NOUN
aiua-5759	36	23	08/04/16	08/04/16	PROPN
aiua-5759	36	24	11:33	11:33	NUM
aiua-5759	36	25	pagina	pagina	NOUN
aiua-5759	36	26	72	72	NUM
aiua-5759	36	27	73archivio	73archivio	NUM
aiua-5759	36	28	italiano	italiano	NOUN
aiua-5759	36	29	di	di	X
aiua-5759	36	30	urologia	urologia	PROPN
aiua-5759	36	31	e	e	PROPN
aiua-5759	36	32	andrologia	andrologia	NOUN
aiua-5759	36	33	2016	2016	NUM
aiua-5759	36	34	;	;	PUNCT
aiua-5759	36	35	88	88	NUM
aiua-5759	36	36	,	,	PUNCT
aiua-5759	36	37	1	1	NUM
aiua-5759	36	38	letter	letter	NOUN
aiua-5759	36	39	to	to	ADP
aiua-5759	36	40	editors	editor	NOUN
aiua-5759	36	41	survival	survival	NOUN
aiua-5759	36	42	(	(	PUNCT
aiua-5759	36	43	rpfs	rpfs	PROPN
aiua-5759	36	44	)	)	PUNCT
aiua-5759	36	45	,	,	PUNCT
aiua-5759	36	46	which	which	PRON
aiua-5759	36	47	was	be	AUX
aiua-5759	36	48	defined	define	VERB
aiua-5759	36	49	as	as	ADP
aiua-5759	36	50	the	the	DET
aiua-5759	36	51	time	time	NOUN
aiua-5759	36	52	between	between	ADP
aiua-5759	36	53	the	the	DET
aiua-5759	36	54	date	date	NOUN
aiua-5759	36	55	of	of	ADP
aiua-5759	36	56	randomization	randomization	NOUN
aiua-5759	36	57	and	and	CCONJ
aiua-5759	36	58	the	the	DET
aiua-5759	36	59	first	first	ADJ
aiua-5759	36	60	date	date	NOUN
aiua-5759	36	61	of	of	ADP
aiua-5759	36	62	radiographic	radiographic	ADJ
aiua-5759	36	63	progression	progression	NOUN
aiua-5759	36	64	.	.	PUNCT
aiua-5759	37	1	perletti	perletti	PROPN
aiua-5759	37	2	et	et	PROPN
aiua-5759	37	3	al	al	PROPN
aiua-5759	37	4	.	.	PROPN
aiua-5759	37	5	stated	state	VERB
aiua-5759	37	6	that	that	SCONJ
aiua-5759	37	7	rpfs	rpf	NOUN
aiua-5759	37	8	data	datum	NOUN
aiua-5759	37	9	were	be	AUX
aiua-5759	37	10	not	not	PART
aiua-5759	37	11	available	available	ADJ
aiua-5759	37	12	for	for	ADP
aiua-5759	37	13	the	the	DET
aiua-5759	37	14	tropic	tropic	NOUN
aiua-5759	37	15	study	study	NOUN
aiua-5759	37	16	.	.	PUNCT
aiua-5759	38	1	in	in	ADP
aiua-5759	38	2	fact	fact	NOUN
aiua-5759	38	3	a	a	DET
aiua-5759	38	4	composite	composite	ADJ
aiua-5759	38	5	pfs	pf	VERB
aiua-5759	38	6	endpoint	endpoint	NOUN
aiua-5759	38	7	was	be	AUX
aiua-5759	38	8	reported	report	VERB
aiua-5759	38	9	for	for	ADP
aiua-5759	38	10	the	the	DET
aiua-5759	38	11	tropic	tropic	NOUN
aiua-5759	38	12	trial	trial	NOUN
aiua-5759	38	13	,	,	PUNCT
aiua-5759	38	14	defined	define	VERB
aiua-5759	38	15	as	as	ADP
aiua-5759	38	16	the	the	DET
aiua-5759	38	17	time	time	NOUN
aiua-5759	38	18	between	between	ADP
aiua-5759	38	19	randomization	randomization	NOUN
aiua-5759	38	20	and	and	CCONJ
aiua-5759	38	21	progression	progression	NOUN
aiua-5759	38	22	measured	measure	VERB
aiua-5759	38	23	by	by	ADP
aiua-5759	38	24	psa	psa	NOUN
aiua-5759	38	25	progression	progression	NOUN
aiua-5759	38	26	,	,	PUNCT
aiua-5759	38	27	tumor	tumor	NOUN
aiua-5759	38	28	/	/	SYM
aiua-5759	38	29	radiological	radiological	ADJ
aiua-5759	38	30	progression	progression	NOUN
aiua-5759	38	31	,	,	PUNCT
aiua-5759	38	32	pain	pain	NOUN
aiua-5759	38	33	/	/	SYM
aiua-5759	38	34	symptomatic	symptomatic	ADJ
aiua-5759	38	35	progression	progression	NOUN
aiua-5759	38	36	,	,	PUNCT
aiua-5759	38	37	or	or	CCONJ
aiua-5759	38	38	death	death	NOUN
aiua-5759	38	39	(	(	PUNCT
aiua-5759	38	40	1	1	NUM
aiua-5759	38	41	)	)	PUNCT
aiua-5759	38	42	.	.	PUNCT
aiua-5759	39	1	median	median	ADJ
aiua-5759	39	2	time	time	NOUN
aiua-5759	39	3	to	to	ADP
aiua-5759	39	4	tumor	tumor	NOUN
aiua-5759	39	5	progression	progression	NOUN
aiua-5759	39	6	was	be	AUX
aiua-5759	39	7	also	also	ADV
aiua-5759	39	8	reported	report	VERB
aiua-5759	39	9	using	use	VERB
aiua-5759	39	10	recist	recist	NOUN
aiua-5759	39	11	criteria	criterion	NOUN
aiua-5759	39	12	(	(	PUNCT
aiua-5759	39	13	1	1	NUM
aiua-5759	39	14	,	,	PUNCT
aiua-5759	39	15	3	3	NUM
aiua-5759	39	16	)	)	PUNCT
aiua-5759	39	17	.	.	PUNCT
aiua-5759	40	1	thus	thus	ADV
aiua-5759	40	2	,	,	PUNCT
aiua-5759	40	3	the	the	DET
aiua-5759	40	4	definition	definition	NOUN
aiua-5759	40	5	of	of	ADP
aiua-5759	40	6	time	time	NOUN
aiua-5759	40	7	to	to	ADP
aiua-5759	40	8	tumor	tumor	NOUN
aiua-5759	40	9	progression	progression	NOUN
aiua-5759	40	10	used	use	VERB
aiua-5759	40	11	in	in	ADP
aiua-5759	40	12	the	the	DET
aiua-5759	40	13	tropic	tropic	NOUN
aiua-5759	40	14	study	study	NOUN
aiua-5759	40	15	is	be	AUX
aiua-5759	40	16	aligned	align	VERB
aiua-5759	40	17	with	with	ADP
aiua-5759	40	18	the	the	DET
aiua-5759	40	19	definition	definition	NOUN
aiua-5759	40	20	of	of	ADP
aiua-5759	40	21	rpfs	rpf	NOUN
aiua-5759	40	22	used	use	VERB
aiua-5759	40	23	by	by	ADP
aiua-5759	40	24	perletti	perletti	PROPN
aiua-5759	40	25	et	et	PROPN
aiua-5759	40	26	al	al	PROPN
aiua-5759	40	27	.	.	PROPN
aiua-5759	40	28	,	,	PUNCT
aiua-5759	40	29	and	and	CCONJ
aiua-5759	40	30	these	these	DET
aiua-5759	40	31	tropic	tropic	NOUN
aiua-5759	40	32	data	datum	NOUN
aiua-5759	40	33	could	could	AUX
aiua-5759	40	34	have	have	AUX
aiua-5759	40	35	been	be	AUX
aiua-5759	40	36	included	include	VERB
aiua-5759	40	37	in	in	ADP
aiua-5759	40	38	their	their	PRON
aiua-5759	40	39	assessment	assessment	NOUN
aiua-5759	40	40	.	.	PUNCT
aiua-5759	41	1	(	(	PUNCT
aiua-5759	41	2	remark	remark	NOUN
aiua-5759	41	3	2	2	NUM
aiua-5759	41	4	)	)	PUNCT
aiua-5759	41	5	finally	finally	ADV
aiua-5759	41	6	,	,	PUNCT
aiua-5759	41	7	in	in	ADP
aiua-5759	41	8	their	their	PRON
aiua-5759	41	9	conclusions	conclusion	NOUN
aiua-5759	41	10	,	,	PUNCT
aiua-5759	41	11	perletti	perletti	PROPN
aiua-5759	41	12	et	et	PROPN
aiua-5759	41	13	al	al	PROPN
aiua-5759	41	14	.	.	PROPN
aiua-5759	42	1	note	note	VERB
aiua-5759	42	2	that	that	SCONJ
aiua-5759	42	3	compared	compare	VERB
aiua-5759	42	4	with	with	ADP
aiua-5759	42	5	control	control	NOUN
aiua-5759	42	6	cohorts	cohort	NOUN
aiua-5759	42	7	in	in	ADP
aiua-5759	42	8	the	the	DET
aiua-5759	42	9	different	different	ADJ
aiua-5759	42	10	studies	study	NOUN
aiua-5759	42	11	,	,	PUNCT
aiua-5759	42	12	survival	survival	NOUN
aiua-5759	42	13	advantages	advantage	NOUN
aiua-5759	42	14	were	be	AUX
aiua-5759	42	15	4.8	4.8	NUM
aiua-5759	42	16	months	month	NOUN
aiua-5759	42	17	for	for	ADP
aiua-5759	42	18	enzalutamide	enzalutamide	NOUN
aiua-5759	42	19	,	,	PUNCT
aiua-5759	42	20	4.6	4.6	NUM
aiua-5759	42	21	months	month	NOUN
aiua-5759	42	22	for	for	ADP
aiua-5759	42	23	abiraterone	abiraterone	NOUN
aiua-5759	42	24	and	and	CCONJ
aiua-5759	42	25	2.4	2.4	NUM
aiua-5759	42	26	months	month	NOUN
aiua-5759	42	27	for	for	ADP
aiua-5759	42	28	cabazitaxel	cabazitaxel	PROPN
aiua-5759	42	29	.	.	PUNCT
aiua-5759	43	1	we	we	PRON
aiua-5759	43	2	would	would	AUX
aiua-5759	43	3	like	like	VERB
aiua-5759	43	4	to	to	PART
aiua-5759	43	5	point	point	VERB
aiua-5759	43	6	out	out	ADP
aiua-5759	43	7	that	that	SCONJ
aiua-5759	43	8	absolute	absolute	ADJ
aiua-5759	43	9	differences	difference	NOUN
aiua-5759	43	10	in	in	ADP
aiua-5759	43	11	median	median	PROPN
aiua-5759	43	12	os	os	NOUN
aiua-5759	43	13	between	between	ADP
aiua-5759	43	14	such	such	ADJ
aiua-5759	43	15	different	different	ADJ
aiua-5759	43	16	clinical	clinical	ADJ
aiua-5759	43	17	trials	trial	NOUN
aiua-5759	43	18	should	should	AUX
aiua-5759	43	19	not	not	PART
aiua-5759	43	20	be	be	AUX
aiua-5759	43	21	compared	compare	VERB
aiua-5759	43	22	;	;	PUNCT
aiua-5759	43	23	furthermore	furthermore	ADV
aiua-5759	43	24	it	it	PRON
aiua-5759	43	25	must	must	AUX
aiua-5759	43	26	be	be	AUX
aiua-5759	43	27	made	make	VERB
aiua-5759	43	28	clear	clear	ADJ
aiua-5759	43	29	that	that	SCONJ
aiua-5759	43	30	the	the	DET
aiua-5759	43	31	control	control	NOUN
aiua-5759	43	32	arms	arm	NOUN
aiua-5759	43	33	in	in	ADP
aiua-5759	43	34	these	these	DET
aiua-5759	43	35	trials	trial	NOUN
aiua-5759	43	36	are	be	AUX
aiua-5759	43	37	quite	quite	ADV
aiua-5759	43	38	different	different	ADJ
aiua-5759	43	39	.	.	PUNCT
aiua-5759	44	1	the	the	DET
aiua-5759	44	2	control	control	NOUN
aiua-5759	44	3	arms	arm	NOUN
aiua-5759	44	4	of	of	ADP
aiua-5759	44	5	the	the	DET
aiua-5759	44	6	enzalutamide	enzalutamide	NOUN
aiua-5759	44	7	and	and	CCONJ
aiua-5759	44	8	abiraterone	abiraterone	NOUN
aiua-5759	44	9	clinical	clinical	ADJ
aiua-5759	44	10	trials	trial	NOUN
aiua-5759	44	11	received	receive	VERB
aiua-5759	44	12	placebo	placebo	NOUN
aiua-5759	44	13	,	,	PUNCT
aiua-5759	44	14	whereas	whereas	SCONJ
aiua-5759	44	15	in	in	ADP
aiua-5759	44	16	the	the	DET
aiua-5759	44	17	cabazitaxel	cabazitaxel	PROPN
aiua-5759	44	18	trial	trial	NOUN
aiua-5759	44	19	the	the	DET
aiua-5759	44	20	control	control	NOUN
aiua-5759	44	21	arm	arm	NOUN
aiua-5759	44	22	received	receive	VERB
aiua-5759	44	23	the	the	DET
aiua-5759	44	24	cytotoxic	cytotoxic	ADJ
aiua-5759	44	25	agent	agent	NOUN
aiua-5759	44	26	,	,	PUNCT
aiua-5759	44	27	mitoxantrone	mitoxantrone	NOUN
aiua-5759	44	28	,	,	PUNCT
aiua-5759	44	29	which	which	PRON
aiua-5759	44	30	has	have	VERB
aiua-5759	44	31	antitumor	antitumor	NOUN
aiua-5759	44	32	activity	activity	NOUN
aiua-5759	44	33	in	in	ADP
aiua-5759	44	34	some	some	DET
aiua-5759	44	35	patients	patient	NOUN
aiua-5759	44	36	.	.	PUNCT
aiua-5759	45	1	(	(	PUNCT
aiua-5759	45	2	remark	remark	NOUN
aiua-5759	45	3	3	3	NUM
aiua-5759	45	4	)	)	PUNCT
aiua-5759	45	5	overall	overall	ADV
aiua-5759	45	6	,	,	PUNCT
aiua-5759	45	7	we	we	PRON
aiua-5759	45	8	commend	commend	VERB
aiua-5759	45	9	perletti	perletti	NOUN
aiua-5759	45	10	et	et	PROPN
aiua-5759	45	11	al	al	PROPN
aiua-5759	45	12	.	.	PROPN
aiua-5759	46	1	for	for	ADP
aiua-5759	46	2	their	their	PRON
aiua-5759	46	3	attempts	attempt	NOUN
aiua-5759	46	4	to	to	PART
aiua-5759	46	5	provide	provide	VERB
aiua-5759	46	6	a	a	DET
aiua-5759	46	7	detailed	detailed	ADJ
aiua-5759	46	8	interpretation	interpretation	NOUN
aiua-5759	46	9	and	and	CCONJ
aiua-5759	46	10	comparison	comparison	NOUN
aiua-5759	46	11	of	of	ADP
aiua-5759	46	12	key	key	ADJ
aiua-5759	46	13	trials	trial	NOUN
aiua-5759	46	14	in	in	ADP
aiua-5759	46	15	the	the	DET
aiua-5759	46	16	rapidly	rapidly	ADV
aiua-5759	46	17	evolving	evolve	VERB
aiua-5759	46	18	field	field	NOUN
aiua-5759	46	19	of	of	ADP
aiua-5759	46	20	mcrpc	mcrpc	PROPN
aiua-5759	46	21	treatment	treatment	NOUN
aiua-5759	46	22	.	.	PUNCT
aiua-5759	47	1	we	we	PRON
aiua-5759	47	2	hope	hope	VERB
aiua-5759	47	3	that	that	SCONJ
aiua-5759	47	4	our	our	PRON
aiua-5759	47	5	clarifications	clarification	NOUN
aiua-5759	47	6	about	about	ADP
aiua-5759	47	7	the	the	DET
aiua-5759	47	8	design	design	NOUN
aiua-5759	47	9	and	and	CCONJ
aiua-5759	47	10	conduct	conduct	NOUN
aiua-5759	47	11	of	of	ADP
aiua-5759	47	12	the	the	DET
aiua-5759	47	13	tropic	tropic	NOUN
aiua-5759	47	14	study	study	NOUN
aiua-5759	47	15	will	will	AUX
aiua-5759	47	16	enable	enable	VERB
aiua-5759	47	17	its	its	PRON
aiua-5759	47	18	important	important	ADJ
aiua-5759	47	19	findings	finding	NOUN
aiua-5759	47	20	to	to	PART
aiua-5759	47	21	be	be	AUX
aiua-5759	47	22	better	well	ADV
aiua-5759	47	23	understood	understand	VERB
aiua-5759	47	24	.	.	PUNCT
aiua-5759	48	1	references	reference	NOUN
aiua-5759	48	2	1	1	NUM
aiua-5759	48	3	.	.	X
aiua-5759	48	4	de	de	X
aiua-5759	48	5	bono	bono	X
aiua-5759	48	6	js	js	PROPN
aiua-5759	48	7	,	,	PUNCT
aiua-5759	48	8	oudard	oudard	ADJ
aiua-5759	48	9	s	s	PROPN
aiua-5759	48	10	,	,	PUNCT
aiua-5759	48	11	ozguroglu	ozguroglu	PROPN
aiua-5759	48	12	m	m	PROPN
aiua-5759	48	13	,	,	PUNCT
aiua-5759	48	14	et	et	PROPN
aiua-5759	48	15	al	al	PROPN
aiua-5759	48	16	.	.	PROPN
aiua-5759	48	17	prednisone	prednisone	PROPN
aiua-5759	48	18	plus	plus	CCONJ
aiua-5759	48	19	cabazitaxel	cabazitaxel	PROPN
aiua-5759	48	20	or	or	CCONJ
aiua-5759	48	21	mitoxantrone	mitoxantrone	NOUN
aiua-5759	48	22	for	for	ADP
aiua-5759	48	23	metastatic	metastatic	ADJ
aiua-5759	48	24	castration	castration	NOUN
aiua-5759	48	25	-	-	PUNCT
aiua-5759	48	26	resistant	resistant	ADJ
aiua-5759	48	27	prostate	prostate	NOUN
aiua-5759	48	28	cancer	cancer	NOUN
aiua-5759	48	29	progressing	progressing	NOUN
aiua-5759	48	30	after	after	ADP
aiua-5759	48	31	docetaxel	docetaxel	NOUN
aiua-5759	48	32	treatment	treatment	NOUN
aiua-5759	48	33	:	:	PUNCT
aiua-5759	48	34	a	a	DET
aiua-5759	48	35	randomized	randomize	VERB
aiua-5759	48	36	open	open	ADJ
aiua-5759	48	37	-	-	PUNCT
aiua-5759	48	38	label	label	NOUN
aiua-5759	48	39	trial	trial	NOUN
aiua-5759	48	40	.	.	PUNCT
aiua-5759	49	1	lancet	lancet	PROPN
aiua-5759	49	2	.	.	PUNCT
aiua-5759	50	1	2010	2010	NUM
aiua-5759	50	2	;	;	PUNCT
aiua-5759	50	3	376:1147	376:1147	NUM
aiua-5759	50	4	-	-	SYM
aiua-5759	50	5	54	54	NUM
aiua-5759	50	6	.	.	PUNCT
aiua-5759	51	1	2	2	NUM
aiua-5759	51	2	.	.	X
aiua-5759	52	1	bahl	bahl	PROPN
aiua-5759	52	2	a	a	PRON
aiua-5759	52	3	,	,	PUNCT
aiua-5759	52	4	oudard	oudard	ADJ
aiua-5759	52	5	s	s	PROPN
aiua-5759	52	6	,	,	PUNCT
aiua-5759	52	7	tombal	tombal	PROPN
aiua-5759	52	8	b	b	NOUN
aiua-5759	52	9	,	,	PUNCT
aiua-5759	52	10	et	et	PROPN
aiua-5759	52	11	al	al	PROPN
aiua-5759	52	12	.	.	PROPN
aiua-5759	52	13	impact	impact	NOUN
aiua-5759	52	14	of	of	ADP
aiua-5759	52	15	cabazitaxel	cabazitaxel	PROPN
aiua-5759	52	16	on	on	ADP
aiua-5759	52	17	2	2	NUM
aiua-5759	52	18	-	-	PUNCT
aiua-5759	52	19	year	year	NOUN
aiua-5759	52	20	survival	survival	NOUN
aiua-5759	52	21	and	and	CCONJ
aiua-5759	52	22	palliation	palliation	NOUN
aiua-5759	52	23	of	of	ADP
aiua-5759	52	24	tumour	tumour	NOUN
aiua-5759	52	25	-	-	PUNCT
aiua-5759	52	26	related	relate	VERB
aiua-5759	52	27	pain	pain	NOUN
aiua-5759	52	28	in	in	ADP
aiua-5759	52	29	men	man	NOUN
aiua-5759	52	30	with	with	ADP
aiua-5759	52	31	metastatic	metastatic	ADJ
aiua-5759	52	32	castration	castration	NOUN
aiua-5759	52	33	-	-	PUNCT
aiua-5759	52	34	resistant	resistant	ADJ
aiua-5759	52	35	prostate	prostate	NOUN
aiua-5759	52	36	cancer	cancer	NOUN
aiua-5759	52	37	treated	treat	VERB
aiua-5759	52	38	in	in	ADP
aiua-5759	52	39	the	the	DET
aiua-5759	52	40	tropic	tropic	NOUN
aiua-5759	52	41	trial	trial	NOUN
aiua-5759	52	42	.	.	PUNCT
aiua-5759	53	1	ann	ann	PROPN
aiua-5759	53	2	oncol	oncol	PROPN
aiua-5759	53	3	.	.	PUNCT
aiua-5759	54	1	2013	2013	NUM
aiua-5759	54	2	;	;	PUNCT
aiua-5759	54	3	24:2402	24:2402	X
aiua-5759	54	4	-	-	SYM
aiua-5759	54	5	8	8	NUM
aiua-5759	54	6	.	.	NOUN
aiua-5759	55	1	3	3	X
aiua-5759	55	2	.	.	X
aiua-5759	55	3	therasse	therasse	PROPN
aiua-5759	55	4	p	p	NOUN
aiua-5759	55	5	,	,	PUNCT
aiua-5759	55	6	arbuck	arbuck	ADJ
aiua-5759	55	7	sg	sg	PROPN
aiua-5759	55	8	,	,	PUNCT
aiua-5759	55	9	eisenhauer	eisenhauer	NOUN
aiua-5759	55	10	ea	ea	PROPN
aiua-5759	55	11	,	,	PUNCT
aiua-5759	55	12	et	et	PROPN
aiua-5759	55	13	al	al	PROPN
aiua-5759	55	14	.	.	PUNCT
aiua-5759	56	1	new	new	ADJ
aiua-5759	56	2	guidelines	guideline	NOUN
aiua-5759	56	3	to	to	PART
aiua-5759	56	4	evaluate	evaluate	VERB
aiua-5759	56	5	the	the	DET
aiua-5759	56	6	response	response	NOUN
aiua-5759	56	7	to	to	ADP
aiua-5759	56	8	treatment	treatment	NOUN
aiua-5759	56	9	in	in	ADP
aiua-5759	56	10	solid	solid	ADJ
aiua-5759	56	11	tumors	tumor	NOUN
aiua-5759	56	12	.	.	PUNCT
aiua-5759	57	1	european	european	ADJ
aiua-5759	57	2	organization	organization	PROPN
aiua-5759	57	3	for	for	ADP
aiua-5759	57	4	research	research	NOUN
aiua-5759	57	5	and	and	CCONJ
aiua-5759	57	6	treatment	treatment	NOUN
aiua-5759	57	7	of	of	ADP
aiua-5759	57	8	cancer	cancer	NOUN
aiua-5759	57	9	,	,	PUNCT
aiua-5759	57	10	national	national	PROPN
aiua-5759	57	11	cancer	cancer	PROPN
aiua-5759	57	12	institute	institute	PROPN
aiua-5759	57	13	of	of	ADP
aiua-5759	57	14	the	the	DET
aiua-5759	57	15	united	united	PROPN
aiua-5759	57	16	states	states	PROPN
aiua-5759	57	17	,	,	PUNCT
aiua-5759	57	18	national	national	PROPN
aiua-5759	57	19	cancer	cancer	PROPN
aiua-5759	57	20	institute	institute	PROPN
aiua-5759	57	21	of	of	ADP
aiua-5759	57	22	canada	canada	PROPN
aiua-5759	57	23	.	.	PUNCT
aiua-5759	58	1	j	j	PROPN
aiua-5759	58	2	natl	natl	PROPN
aiua-5759	58	3	cancer	cancer	PROPN
aiua-5759	58	4	inst	inst	PROPN
aiua-5759	58	5	.	.	PROPN
aiua-5759	58	6	2000	2000	NUM
aiua-5759	58	7	;	;	PUNCT
aiua-5759	58	8	92:205	92:205	NUM
aiua-5759	58	9	-	-	SYM
aiua-5759	58	10	16	16	NUM
aiua-5759	58	11	.	.	PUNCT
aiua-5759	59	1	acknowledgements	acknowledgement	NOUN
aiua-5759	59	2	the	the	DET
aiua-5759	59	3	tropic	tropic	NOUN
aiua-5759	59	4	study	study	NOUN
aiua-5759	59	5	was	be	AUX
aiua-5759	59	6	sponsored	sponsor	VERB
aiua-5759	59	7	by	by	ADP
aiua-5759	59	8	sanofi	sanofi	PROPN
aiua-5759	59	9	.	.	PUNCT
aiua-5759	60	1	editorial	editorial	ADJ
aiua-5759	60	2	support	support	NOUN
aiua-5759	60	3	in	in	ADP
aiua-5759	60	4	the	the	DET
aiua-5759	60	5	preparation	preparation	NOUN
aiua-5759	60	6	of	of	ADP
aiua-5759	60	7	this	this	DET
aiua-5759	60	8	letter	letter	NOUN
aiua-5759	60	9	was	be	AUX
aiua-5759	60	10	provided	provide	VERB
aiua-5759	60	11	by	by	ADP
aiua-5759	60	12	danielle	danielle	PROPN
aiua-5759	60	13	lindley	lindley	PROPN
aiua-5759	60	14	of	of	ADP
aiua-5759	60	15	meditech	meditech	PROPN
aiua-5759	60	16	media	medium	NOUN
aiua-5759	60	17	funded	fund	VERB
aiua-5759	60	18	by	by	ADP
aiua-5759	60	19	sanofi	sanofi	PROPN
aiua-5759	60	20	.	.	PUNCT
aiua-5759	61	1	the	the	DET
aiua-5759	61	2	authors	author	NOUN
aiua-5759	61	3	,	,	PUNCT
aiua-5759	61	4	individuallyand	individuallyand	NOUN
aiua-5759	61	5	collectively	collectively	ADV
aiua-5759	61	6	,	,	PUNCT
aiua-5759	61	7	are	be	AUX
aiua-5759	61	8	responsible	responsible	ADJ
aiua-5759	61	9	for	for	ADP
aiua-5759	61	10	all	all	DET
aiua-5759	61	11	content	content	NOUN
aiua-5759	61	12	and	and	CCONJ
aiua-5759	61	13	editorial	editorial	ADJ
aiua-5759	61	14	decisions	decision	NOUN
aiua-5759	61	15	and	and	CCONJ
aiua-5759	61	16	received	receive	VERB
aiua-5759	61	17	no	no	DET
aiua-5759	61	18	payment	payment	NOUN
aiua-5759	61	19	from	from	ADP
aiua-5759	61	20	sanofi	sanofi	PROPN
aiua-5759	61	21	related	relate	VERB
aiua-5759	61	22	to	to	ADP
aiua-5759	61	23	the	the	DET
aiua-5759	61	24	development	development	NOUN
aiua-5759	61	25	of	of	ADP
aiua-5759	61	26	this	this	DET
aiua-5759	61	27	letter	letter	NOUN
aiua-5759	61	28	.	.	PUNCT
aiua-5759	62	1	johann	johann	PROPN
aiua-5759	62	2	de	de	X
aiua-5759	62	3	bono	bono	X
aiua-5759	62	4	1	1	NUM
aiua-5759	62	5	,	,	PUNCT
aiua-5759	62	6	liji	liji	PROPN
aiua-5759	62	7	shen	shen	NOUN
aiua-5759	62	8	2	2	NUM
aiua-5759	62	9	,	,	PUNCT
aiua-5759	62	10	oliver	oliver	PROPN
aiua-5759	62	11	sartor	sartor	PROPN
aiua-5759	62	12	3	3	NUM
aiua-5759	62	13	1	1	NUM
aiua-5759	62	14	royal	royal	PROPN
aiua-5759	62	15	marsden	marsden	PROPN
aiua-5759	62	16	nhs	nhs	PROPN
aiua-5759	62	17	foundation	foundation	PROPN
aiua-5759	62	18	trust	trust	PROPN
aiua-5759	62	19	and	and	CCONJ
aiua-5759	62	20	the	the	DET
aiua-5759	62	21	institute	institute	NOUN
aiua-5759	62	22	of	of	ADP
aiua-5759	62	23	cancer	cancer	PROPN
aiua-5759	62	24	research	research	PROPN
aiua-5759	62	25	,	,	PUNCT
aiua-5759	62	26	sutton	sutton	PROPN
aiua-5759	62	27	,	,	PUNCT
aiua-5759	62	28	uk	uk	PROPN
aiua-5759	62	29	;	;	PUNCT
aiua-5759	62	30	2	2	NUM
aiua-5759	62	31	sanofi	sanofi	NOUN
aiua-5759	62	32	,	,	PUNCT
aiua-5759	62	33	bridgewater	bridgewater	PROPN
aiua-5759	62	34	,	,	PUNCT
aiua-5759	62	35	nj	nj	PROPN
aiua-5759	62	36	,	,	PUNCT
aiua-5759	62	37	usa	usa	PROPN
aiua-5759	62	38	;	;	PUNCT
aiua-5759	62	39	3	3	NUM
aiua-5759	62	40	tulane	tulane	NOUN
aiua-5759	62	41	university	university	PROPN
aiua-5759	62	42	medical	medical	ADJ
aiua-5759	62	43	school	school	NOUN
aiua-5759	62	44	,	,	PUNCT
aiua-5759	62	45	new	new	PROPN
aiua-5759	62	46	orleans	orleans	PROPN
aiua-5759	62	47	,	,	PUNCT
aiua-5759	62	48	la	la	PROPN
aiua-5759	62	49	,	,	PUNCT
aiua-5759	62	50	usa	usa	PROPN
aiua-5759	62	51	.	.	PROPN
aiua-5759	62	52	correspondence	correspondence	PROPN
aiua-5759	62	53	johann	johann	PROPN
aiua-5759	62	54	sebastian	sebastian	PROPN
aiua-5759	62	55	de	de	X
aiua-5759	62	56	bono	bono	X
aiua-5759	62	57	,	,	PUNCT
aiua-5759	62	58	mbchb	mbchb	PROPN
aiua-5759	62	59	msc	msc	PROPN
aiua-5759	62	60	phd	phd	PROPN
aiua-5759	62	61	frcp	frcp	PROPN
aiua-5759	62	62	fmedsci	fmedsci	PROPN
aiua-5759	62	63	(	(	PUNCT
aiua-5759	62	64	corresponding	corresponding	ADJ
aiua-5759	62	65	author	author	NOUN
aiua-5759	62	66	)	)	PUNCT
aiua-5759	62	67	johann.de-bono@icr.ac.uk	johann.de-bono@icr.ac.uk	PROPN
aiua-5759	62	68	royal	royal	ADJ
aiua-5759	62	69	marsden	marsden	PROPN
aiua-5759	62	70	and	and	CCONJ
aiua-5759	62	71	the	the	DET
aiua-5759	62	72	institute	institute	PROPN
aiua-5759	62	73	of	of	ADP
aiua-5759	62	74	cancer	cancer	PROPN
aiua-5759	62	75	research	research	PROPN
aiua-5759	62	76	,	,	PUNCT
aiua-5759	62	77	london	london	PROPN
aiua-5759	62	78	,	,	PUNCT
aiua-5759	62	79	downs	down	NOUN
aiua-5759	62	80	road	road	NOUN
aiua-5759	62	81	,	,	PUNCT
aiua-5759	62	82	sutton	sutton	PROPN
aiua-5759	62	83	,	,	PUNCT
aiua-5759	62	84	surrey	surrey	PROPN
aiua-5759	62	85	sm2	sm2	VERB
aiua-5759	62	86	5pt	5pt	ADV
aiua-5759	62	87	,	,	PUNCT
aiua-5759	62	88	uk	uk	PROPN
aiua-5759	62	89	liji	liji	PROPN
aiua-5759	62	90	shen	shen	PROPN
aiua-5759	62	91	liji.shen@sanofi.com	liji.shen@sanofi.com	PROPN
aiua-5759	62	92	sanofi	sanofi	PROPN
aiua-5759	62	93	,	,	PUNCT
aiua-5759	62	94	bridgewater	bridgewater	PROPN
aiua-5759	62	95	,	,	PUNCT
aiua-5759	62	96	nj	nj	PROPN
aiua-5759	62	97	,	,	PUNCT
aiua-5759	62	98	usa	usa	PROPN
aiua-5759	62	99	oliver	oliver	PROPN
aiua-5759	62	100	sartor	sartor	PROPN
aiua-5759	62	101	osartor@tulane.edu	osartor@tulane.edu	PROPN
aiua-5759	62	102	tulane	tulane	PROPN
aiua-5759	62	103	university	university	PROPN
aiua-5759	62	104	medical	medical	ADJ
aiua-5759	62	105	school	school	NOUN
aiua-5759	62	106	,	,	PUNCT
aiua-5759	62	107	new	new	PROPN
aiua-5759	62	108	orleans	orleans	PROPN
aiua-5759	62	109	,	,	PUNCT
aiua-5759	62	110	la	la	PROPN
aiua-5759	62	111	,	,	PUNCT
aiua-5759	62	112	usa	usa	PROPN
aiua-5759	62	113	de	de	X
aiua-5759	62	114	bono	bono	X
aiua-5759	62	115	letter_stesura	letter_stesura	NOUN
aiua-5759	62	116	seveso	seveso	NOUN
aiua-5759	62	117	08/04/16	08/04/16	PROPN
aiua-5759	62	118	11:33	11:33	NUM
aiua-5759	62	119	pagina	pagina	NOUN
aiua-5759	62	120	73	73	NUM