id	sid	tid	token	lemma	pos
aiua-8788	1	1	cop+ed+fisse	cop+ed+fisse	NOUN
aiua-8788	1	2	2006	2006	NUM
aiua-8788	1	3	211archivio	211archivio	NOUN
aiua-8788	1	4	italiano	italiano	NOUN
aiua-8788	1	5	di	di	NOUN
aiua-8788	1	6	urologia	urologia	PROPN
aiua-8788	1	7	e	e	PROPN
aiua-8788	1	8	andrologia	andrologia	NOUN
aiua-8788	1	9	2020	2020	NUM
aiua-8788	1	10	;	;	PUNCT
aiua-8788	1	11	92	92	NUM
aiua-8788	1	12	,	,	PUNCT
aiua-8788	1	13	3	3	NUM
aiua-8788	1	14	case	case	NOUN
aiua-8788	1	15	report	report	VERB
aiua-8788	1	16	no	no	DET
aiua-8788	1	17	conflict	conflict	NOUN
aiua-8788	1	18	of	of	ADP
aiua-8788	1	19	interest	interest	NOUN
aiua-8788	1	20	declared	declare	VERB
aiua-8788	1	21	.	.	PUNCT
aiua-8788	2	1	doi	doi	NOUN
aiua-8788	2	2	:	:	PUNCT
aiua-8788	2	3	10.4081	10.4081	NUM
aiua-8788	2	4	/	/	SYM
aiua-8788	2	5	aiua.2020.3.211	aiua.2020.3.211	NOUN
aiua-8788	2	6	primary	primary	ADJ
aiua-8788	2	7	small	small	ADJ
aiua-8788	2	8	-	-	PUNCT
aiua-8788	2	9	cell	cell	NOUN
aiua-8788	2	10	neuroendocrine	neuroendocrine	ADJ
aiua-8788	2	11	carcinoma	carcinoma	NOUN
aiua-8788	2	12	of	of	ADP
aiua-8788	2	13	the	the	DET
aiua-8788	2	14	bladder	bladder	NOUN
aiua-8788	2	15	:	:	PUNCT
aiua-8788	2	16	case	case	NOUN
aiua-8788	2	17	report	report	NOUN
aiua-8788	2	18	and	and	CCONJ
aiua-8788	2	19	literature	literature	PROPN
aiua-8788	2	20	review	review	PROPN
aiua-8788	2	21	valerio	valerio	PROPN
aiua-8788	2	22	olivieri	olivieri	PROPN
aiua-8788	2	23	1	1	NUM
aiua-8788	2	24	,	,	PUNCT
aiua-8788	2	25	valentina	valentina	PROPN
aiua-8788	2	26	fortunati	fortunati	PROPN
aiua-8788	2	27	2	2	NUM
aiua-8788	2	28	,	,	PUNCT
aiua-8788	2	29	luca	luca	PROPN
aiua-8788	2	30	bellei	bellei	NOUN
aiua-8788	2	31	1	1	NUM
aiua-8788	2	32	,	,	PUNCT
aiua-8788	2	33	massimo	massimo	PROPN
aiua-8788	2	34	massarelli	massarelli	PROPN
aiua-8788	2	35	1	1	NUM
aiua-8788	2	36	,	,	PUNCT
aiua-8788	2	37	gabriele	gabriele	PROPN
aiua-8788	2	38	ruggiero	ruggiero	PROPN
aiua-8788	2	39	3	3	NUM
aiua-8788	2	40	,	,	PUNCT
aiua-8788	2	41	danilo	danilo	PROPN
aiua-8788	2	42	abate	abate	VERB
aiua-8788	2	43	3	3	NUM
aiua-8788	2	44	,	,	PUNCT
aiua-8788	2	45	nicoletta	nicoletta	PROPN
aiua-8788	2	46	serra	serra	PROPN
aiua-8788	2	47	3	3	PROPN
aiua-8788	2	48	,	,	PUNCT
aiua-8788	2	49	daniele	daniele	PROPN
aiua-8788	2	50	griffa	griffa	PROPN
aiua-8788	2	51	1	1	NUM
aiua-8788	2	52	,	,	PUNCT
aiua-8788	2	53	3	3	NUM
aiua-8788	2	54	,	,	PUNCT
aiua-8788	2	55	flavio	flavio	PROPN
aiua-8788	2	56	forte	forte	PROPN
aiua-8788	2	57	4	4	NUM
aiua-8788	2	58	,	,	PUNCT
aiua-8788	2	59	emanuele	emanuele	PROPN
aiua-8788	2	60	corongiu	corongiu	PROPN
aiua-8788	2	61	4	4	NUM
aiua-8788	2	62	1	1	NUM
aiua-8788	2	63	division	division	NOUN
aiua-8788	2	64	of	of	ADP
aiua-8788	2	65	urology	urology	NOUN
aiua-8788	2	66	,	,	PUNCT
aiua-8788	2	67	ivrea	ivrea	PROPN
aiua-8788	2	68	hospital	hospital	PROPN
aiua-8788	2	69	(	(	PUNCT
aiua-8788	2	70	asl	asl	PROPN
aiua-8788	2	71	to4	to4	NOUN
aiua-8788	2	72	)	)	PUNCT
aiua-8788	2	73	,	,	PUNCT
aiua-8788	2	74	ivrea	ivrea	PROPN
aiua-8788	2	75	(	(	PUNCT
aiua-8788	2	76	turin	turin	PROPN
aiua-8788	2	77	)	)	PUNCT
aiua-8788	2	78	,	,	PUNCT
aiua-8788	2	79	italy	italy	PROPN
aiua-8788	2	80	;	;	PUNCT
aiua-8788	2	81	2	2	NUM
aiua-8788	2	82	division	division	NOUN
aiua-8788	2	83	of	of	ADP
aiua-8788	2	84	pathology	pathology	NOUN
aiua-8788	2	85	,	,	PUNCT
aiua-8788	2	86	hospital	hospital	NOUN
aiua-8788	2	87	policlinico	policlinico	NOUN
aiua-8788	2	88	of	of	ADP
aiua-8788	2	89	tor	tor	PROPN
aiua-8788	2	90	vergata	vergata	NOUN
aiua-8788	2	91	,	,	PUNCT
aiua-8788	2	92	rome	rome	PROPN
aiua-8788	2	93	,	,	PUNCT
aiua-8788	2	94	italy	italy	PROPN
aiua-8788	2	95	;	;	PUNCT
aiua-8788	2	96	3	3	NUM
aiua-8788	2	97	division	division	NOUN
aiua-8788	2	98	of	of	ADP
aiua-8788	2	99	urology	urology	NOUN
aiua-8788	2	100	,	,	PUNCT
aiua-8788	2	101	ciriè	ciriè	PROPN
aiua-8788	2	102	hospital	hospital	NOUN
aiua-8788	2	103	(	(	PUNCT
aiua-8788	2	104	aslto4	aslto4	NOUN
aiua-8788	2	105	)	)	PUNCT
aiua-8788	2	106	,	,	PUNCT
aiua-8788	2	107	ciriè	ciriè	PROPN
aiua-8788	2	108	(	(	PUNCT
aiua-8788	2	109	turin	turin	PROPN
aiua-8788	2	110	)	)	PUNCT
aiua-8788	2	111	,	,	PUNCT
aiua-8788	2	112	italy	italy	PROPN
aiua-8788	2	113	;	;	PUNCT
aiua-8788	2	114	4	4	NUM
aiua-8788	2	115	division	division	NOUN
aiua-8788	2	116	of	of	ADP
aiua-8788	2	117	urology	urology	NOUN
aiua-8788	2	118	,	,	PUNCT
aiua-8788	2	119	hospital	hospital	NOUN
aiua-8788	2	120	“	"	PUNCT
aiua-8788	2	121	madre	madre	PROPN
aiua-8788	2	122	giuseppina	giuseppina	PROPN
aiua-8788	2	123	vannini	vannini	PROPN
aiua-8788	2	124	”	"	PUNCT
aiua-8788	2	125	,	,	PUNCT
aiua-8788	2	126	rome	rome	PROPN
aiua-8788	2	127	,	,	PUNCT
aiua-8788	2	128	italy	italy	PROPN
aiua-8788	2	129	.	.	PUNCT
aiua-8788	3	1	background	background	NOUN
aiua-8788	3	2	:	:	PUNCT
aiua-8788	3	3	neuroendocrine	neuroendocrine	NOUN
aiua-8788	3	4	tumours	tumours	NOUN
aiua-8788	3	5	(	(	PUNCT
aiua-8788	3	6	net	net	NOUN
aiua-8788	3	7	)	)	PUNCT
aiua-8788	3	8	are	be	AUX
aiua-8788	3	9	extremely	extremely	ADV
aiua-8788	3	10	rare	rare	ADJ
aiua-8788	3	11	and	and	CCONJ
aiua-8788	3	12	aggressive	aggressive	ADJ
aiua-8788	3	13	.	.	PUNCT
aiua-8788	4	1	although	although	SCONJ
aiua-8788	4	2	they	they	PRON
aiua-8788	4	3	commonly	commonly	ADV
aiua-8788	4	4	affect	affect	VERB
aiua-8788	4	5	intestine	intestine	NOUN
aiua-8788	4	6	,	,	PUNCT
aiua-8788	4	7	many	many	ADJ
aiua-8788	4	8	organs	organ	NOUN
aiua-8788	4	9	may	may	AUX
aiua-8788	4	10	be	be	AUX
aiua-8788	4	11	involved	involve	VERB
aiua-8788	4	12	such	such	ADJ
aiua-8788	4	13	as	as	ADP
aiua-8788	4	14	pancreas	pancrea	NOUN
aiua-8788	4	15	,	,	PUNCT
aiua-8788	4	16	lung	lung	NOUN
aiua-8788	4	17	or	or	CCONJ
aiua-8788	4	18	urinary	urinary	ADJ
aiua-8788	4	19	tract	tract	NOUN
aiua-8788	4	20	.	.	PUNCT
aiua-8788	5	1	bladder	bladder	NOUN
aiua-8788	5	2	is	be	AUX
aiua-8788	5	3	rarely	rarely	ADV
aiua-8788	5	4	involved	involve	VERB
aiua-8788	5	5	.	.	PUNCT
aiua-8788	6	1	actually	actually	ADV
aiua-8788	6	2	,	,	PUNCT
aiua-8788	6	3	two	two	NUM
aiua-8788	6	4	main	main	ADJ
aiua-8788	6	5	forms	form	NOUN
aiua-8788	6	6	of	of	ADP
aiua-8788	6	7	bladder	bladder	NOUN
aiua-8788	6	8	net	net	NOUN
aiua-8788	6	9	have	have	AUX
aiua-8788	6	10	been	be	AUX
aiua-8788	6	11	described	describe	VERB
aiua-8788	6	12	:	:	PUNCT
aiua-8788	6	13	small	small	ADJ
aiua-8788	6	14	-	-	PUNCT
aiua-8788	6	15	cell	cell	NOUN
aiua-8788	6	16	and	and	CCONJ
aiua-8788	6	17	large	large	ADJ
aiua-8788	6	18	-	-	PUNCT
aiua-8788	6	19	cell	cell	NOUN
aiua-8788	6	20	.	.	PUNCT
aiua-8788	7	1	the	the	DET
aiua-8788	7	2	first	first	ADJ
aiua-8788	7	3	one	one	NOUN
aiua-8788	7	4	is	be	AUX
aiua-8788	7	5	considered	consider	VERB
aiua-8788	7	6	highly	highly	ADV
aiua-8788	7	7	agressive	agressive	ADJ
aiua-8788	7	8	since	since	SCONJ
aiua-8788	7	9	it	it	PRON
aiua-8788	7	10	shows	show	VERB
aiua-8788	7	11	poor	poor	ADJ
aiua-8788	7	12	oncologic	oncologic	ADJ
aiua-8788	7	13	outcomes	outcome	NOUN
aiua-8788	7	14	being	be	AUX
aiua-8788	7	15	mainly	mainly	ADV
aiua-8788	7	16	diagnosed	diagnose	VERB
aiua-8788	7	17	at	at	ADP
aiua-8788	7	18	advanced	advanced	ADJ
aiua-8788	7	19	stage	stage	NOUN
aiua-8788	7	20	:	:	PUNCT
aiua-8788	7	21	the	the	DET
aiua-8788	7	22	second	second	ADJ
aiua-8788	7	23	one	one	NOUN
aiua-8788	7	24	is	be	AUX
aiua-8788	7	25	extremely	extremely	ADV
aiua-8788	7	26	rare	rare	ADJ
aiua-8788	7	27	and	and	CCONJ
aiua-8788	7	28	equally	equally	ADV
aiua-8788	7	29	aggressive	aggressive	ADJ
aiua-8788	7	30	.	.	PUNCT
aiua-8788	8	1	case	case	NOUN
aiua-8788	8	2	report	report	NOUN
aiua-8788	8	3	:	:	PUNCT
aiua-8788	8	4	a	a	DET
aiua-8788	8	5	78	78	NUM
aiua-8788	8	6	-	-	PUNCT
aiua-8788	8	7	years	year	NOUN
aiua-8788	8	8	-	-	PUNCT
aiua-8788	8	9	old	old	ADJ
aiua-8788	8	10	caucasian	caucasian	ADJ
aiua-8788	8	11	male	male	NOUN
aiua-8788	8	12	presented	present	VERB
aiua-8788	8	13	to	to	ADP
aiua-8788	8	14	our	our	PRON
aiua-8788	8	15	facility	facility	NOUN
aiua-8788	8	16	for	for	ADP
aiua-8788	8	17	lower	low	ADJ
aiua-8788	8	18	urinary	urinary	ADJ
aiua-8788	8	19	tract	tract	NOUN
aiua-8788	8	20	symptoms	symptom	NOUN
aiua-8788	8	21	and	and	CCONJ
aiua-8788	8	22	gross	gross	ADJ
aiua-8788	8	23	hematuria	hematuria	NOUN
aiua-8788	8	24	recently	recently	ADV
aiua-8788	8	25	occurred	occur	VERB
aiua-8788	8	26	.	.	PUNCT
aiua-8788	9	1	he	he	PRON
aiua-8788	9	2	was	be	AUX
aiua-8788	9	3	a	a	DET
aiua-8788	9	4	strong	strong	ADJ
aiua-8788	9	5	smoker	smoker	NOUN
aiua-8788	9	6	since	since	SCONJ
aiua-8788	9	7	many	many	ADJ
aiua-8788	9	8	years	year	NOUN
aiua-8788	9	9	.	.	PUNCT
aiua-8788	10	1	no	no	DET
aiua-8788	10	2	familiarity	familiarity	NOUN
aiua-8788	10	3	for	for	ADP
aiua-8788	10	4	urothelial	urothelial	ADJ
aiua-8788	10	5	cancer	cancer	NOUN
aiua-8788	10	6	was	be	AUX
aiua-8788	10	7	referred	refer	VERB
aiua-8788	10	8	nor	nor	CCONJ
aiua-8788	10	9	previous	previous	ADJ
aiua-8788	10	10	episodes	episode	NOUN
aiua-8788	10	11	of	of	ADP
aiua-8788	10	12	hematuria	hematuria	NOUN
aiua-8788	10	13	until	until	ADP
aiua-8788	10	14	that	that	DET
aiua-8788	10	15	time	time	NOUN
aiua-8788	10	16	.	.	PUNCT
aiua-8788	11	1	citology	citology	NOUN
aiua-8788	11	2	was	be	AUX
aiua-8788	11	3	negative	negative	ADJ
aiua-8788	11	4	;	;	PUNCT
aiua-8788	11	5	outpatient	outpatient	NOUN
aiua-8788	11	6	ultrasound	ultrasound	NOUN
aiua-8788	11	7	of	of	ADP
aiua-8788	11	8	the	the	DET
aiua-8788	11	9	bladder	bladder	NOUN
aiua-8788	11	10	revealed	reveal	VERB
aiua-8788	11	11	a	a	DET
aiua-8788	11	12	3	3	NUM
aiua-8788	11	13	cm	cm	NOUN
aiua-8788	11	14	bladder	bladder	NOUN
aiua-8788	11	15	thickening	thickening	NOUN
aiua-8788	11	16	highly	highly	ADV
aiua-8788	11	17	suspicious	suspicious	ADJ
aiua-8788	11	18	for	for	ADP
aiua-8788	11	19	bladder	bladder	NOUN
aiua-8788	11	20	cancer	cancer	NOUN
aiua-8788	11	21	;	;	PUNCT
aiua-8788	11	22	patient	patient	ADJ
aiua-8788	11	23	underwent	underwent	NOUN
aiua-8788	11	24	tc	tc	NOUN
aiua-8788	11	25	scan	scan	NOUN
aiua-8788	11	26	that	that	PRON
aiua-8788	11	27	confirmed	confirm	VERB
aiua-8788	11	28	the	the	DET
aiua-8788	11	29	bladder	bladder	NOUN
aiua-8788	11	30	lesion	lesion	NOUN
aiua-8788	11	31	.	.	PUNCT
aiua-8788	12	1	a	a	DET
aiua-8788	12	2	transurethral	transurethral	ADJ
aiua-8788	12	3	resection	resection	NOUN
aiua-8788	12	4	of	of	ADP
aiua-8788	12	5	the	the	DET
aiua-8788	12	6	bladder	bladder	NOUN
aiua-8788	12	7	(	(	PUNCT
aiua-8788	12	8	turb	turb	NOUN
aiua-8788	12	9	)	)	PUNCT
aiua-8788	12	10	was	be	AUX
aiua-8788	12	11	performed	perform	VERB
aiua-8788	12	12	.	.	PUNCT
aiua-8788	13	1	after	after	ADP
aiua-8788	13	2	3	3	NUM
aiua-8788	13	3	months	month	NOUN
aiua-8788	13	4	total	total	ADJ
aiua-8788	13	5	body	body	NOUN
aiua-8788	13	6	tc	tc	NOUN
aiua-8788	13	7	showed	show	VERB
aiua-8788	13	8	multiple	multiple	ADJ
aiua-8788	13	9	visceral	visceral	ADJ
aiua-8788	13	10	metastases	metastasis	NOUN
aiua-8788	13	11	also	also	ADV
aiua-8788	13	12	involving	involve	VERB
aiua-8788	13	13	brain	brain	NOUN
aiua-8788	13	14	and	and	CCONJ
aiua-8788	13	15	lymph	lymph	NOUN
aiua-8788	13	16	nodes	node	NOUN
aiua-8788	13	17	.	.	PUNCT
aiua-8788	14	1	best	good	ADJ
aiua-8788	14	2	supportive	supportive	ADJ
aiua-8788	14	3	care	care	NOUN
aiua-8788	14	4	was	be	AUX
aiua-8788	14	5	offered	offer	VERB
aiua-8788	14	6	but	but	CCONJ
aiua-8788	14	7	the	the	DET
aiua-8788	14	8	patient	patient	NOUN
aiua-8788	14	9	died	die	VERB
aiua-8788	14	10	6	6	NUM
aiua-8788	14	11	months	month	NOUN
aiua-8788	14	12	later	later	ADV
aiua-8788	14	13	.	.	PUNCT
aiua-8788	15	1	results	result	NOUN
aiua-8788	15	2	:	:	PUNCT
aiua-8788	15	3	pathology	pathology	NOUN
aiua-8788	15	4	revealed	reveal	VERB
aiua-8788	15	5	a	a	DET
aiua-8788	15	6	mixed	mixed	ADJ
aiua-8788	15	7	bladder	bladder	NOUN
aiua-8788	15	8	tumor	tumor	NOUN
aiua-8788	15	9	:	:	PUNCT
aiua-8788	15	10	30	30	NUM
aiua-8788	15	11	%	%	NOUN
aiua-8788	15	12	of	of	ADP
aiua-8788	15	13	the	the	DET
aiua-8788	15	14	specimen	speciman	NOUN
aiua-8788	15	15	resulted	result	VERB
aiua-8788	15	16	as	as	SCONJ
aiua-8788	15	17	an	an	DET
aiua-8788	15	18	high	high	ADJ
aiua-8788	15	19	-	-	PUNCT
aiua-8788	15	20	grade	grade	NOUN
aiua-8788	15	21	urothelial	urothelial	ADJ
aiua-8788	15	22	cancer	cancer	NOUN
aiua-8788	15	23	(	(	PUNCT
aiua-8788	15	24	g3	g3	NOUN
aiua-8788	15	25	)	)	PUNCT
aiua-8788	15	26	and	and	CCONJ
aiua-8788	15	27	70	70	NUM
aiua-8788	15	28	%	%	NOUN
aiua-8788	15	29	as	as	ADP
aiua-8788	15	30	small	small	ADJ
aiua-8788	15	31	-	-	PUNCT
aiua-8788	15	32	cell	cell	NOUN
aiua-8788	15	33	neuroendocrine	neuroendocrine	NOUN
aiua-8788	15	34	variant.microscopic	variant.microscopic	NOUN
aiua-8788	15	35	muscle	muscle	NOUN
aiua-8788	15	36	involvement	involvement	NOUN
aiua-8788	15	37	was	be	AUX
aiua-8788	15	38	excluded	exclude	VERB
aiua-8788	15	39	.	.	PUNCT
aiua-8788	16	1	conclusions	conclusion	NOUN
aiua-8788	16	2	:	:	PUNCT
aiua-8788	16	3	neuroendocrine	neuroendocrine	ADJ
aiua-8788	16	4	tumors	tumor	NOUN
aiua-8788	16	5	are	be	AUX
aiua-8788	16	6	uncommon	uncommon	ADJ
aiua-8788	16	7	entities	entity	NOUN
aiua-8788	16	8	which	which	PRON
aiua-8788	16	9	origin	origin	VERB
aiua-8788	16	10	from	from	ADP
aiua-8788	16	11	cells	cell	NOUN
aiua-8788	16	12	of	of	ADP
aiua-8788	16	13	neuro	neuro	NOUN
aiua-8788	16	14	-	-	PUNCT
aiua-8788	16	15	endocrine	endocrine	NOUN
aiua-8788	16	16	system	system	NOUN
aiua-8788	16	17	and	and	CCONJ
aiua-8788	16	18	may	may	AUX
aiua-8788	16	19	potentially	potentially	ADV
aiua-8788	16	20	involve	involve	VERB
aiua-8788	16	21	all	all	DET
aiua-8788	16	22	human	human	ADJ
aiua-8788	16	23	tissues	tissue	NOUN
aiua-8788	16	24	.	.	PUNCT
aiua-8788	17	1	neuroendocrine	neuroendocrine	NOUN
aiua-8788	17	2	smallcell	smallcell	VERB
aiua-8788	17	3	carcinoma	carcinoma	NOUN
aiua-8788	17	4	of	of	ADP
aiua-8788	17	5	the	the	DET
aiua-8788	17	6	bladder	bladder	NOUN
aiua-8788	17	7	is	be	AUX
aiua-8788	17	8	a	a	DET
aiua-8788	17	9	non	non	ADJ
aiua-8788	17	10	-	-	ADJ
aiua-8788	17	11	urothelial	urothelial	ADJ
aiua-8788	17	12	histotype	histotype	NOUN
aiua-8788	17	13	:	:	PUNCT
aiua-8788	17	14	it	it	PRON
aiua-8788	17	15	is	be	AUX
aiua-8788	17	16	highly	highly	ADV
aiua-8788	17	17	aggressive	aggressive	ADJ
aiua-8788	17	18	and	and	CCONJ
aiua-8788	17	19	diagnosed	diagnose	VERB
aiua-8788	17	20	mainly	mainly	ADV
aiua-8788	17	21	at	at	ADP
aiua-8788	17	22	advanced	advanced	ADJ
aiua-8788	17	23	stages	stage	NOUN
aiua-8788	17	24	.	.	PUNCT
aiua-8788	18	1	whenever	whenever	SCONJ
aiua-8788	18	2	considering	consider	VERB
aiua-8788	18	3	the	the	DET
aiua-8788	18	4	high	high	ADJ
aiua-8788	18	5	risk	risk	NOUN
aiua-8788	18	6	of	of	ADP
aiua-8788	18	7	metastatic	metastatic	ADJ
aiua-8788	18	8	spread	spread	NOUN
aiua-8788	18	9	and	and	CCONJ
aiua-8788	18	10	the	the	DET
aiua-8788	18	11	poor	poor	ADJ
aiua-8788	18	12	prognosis	prognosis	NOUN
aiua-8788	18	13	,	,	PUNCT
aiua-8788	18	14	a	a	DET
aiua-8788	18	15	multimodal	multimodal	ADJ
aiua-8788	18	16	approach	approach	NOUN
aiua-8788	18	17	is	be	AUX
aiua-8788	18	18	highly	highly	ADV
aiua-8788	18	19	suggested	suggest	VERB
aiua-8788	18	20	.	.	PUNCT
aiua-8788	19	1	turb	turb	PROPN
aiua-8788	19	2	alone	alone	ADV
aiua-8788	19	3	is	be	AUX
aiua-8788	19	4	uneffective	uneffective	ADJ
aiua-8788	19	5	in	in	ADP
aiua-8788	19	6	disease	disease	NOUN
aiua-8788	19	7	control	control	NOUN
aiua-8788	19	8	due	due	ADP
aiua-8788	19	9	to	to	ADP
aiua-8788	19	10	its	its	PRON
aiua-8788	19	11	aggressive	aggressive	ADJ
aiua-8788	19	12	nature	nature	NOUN
aiua-8788	19	13	.	.	PUNCT
aiua-8788	20	1	unless	unless	SCONJ
aiua-8788	20	2	metastatic	metastatic	ADJ
aiua-8788	20	3	,	,	PUNCT
aiua-8788	20	4	radical	radical	ADJ
aiua-8788	20	5	cystectomy	cystectomy	NOUN
aiua-8788	20	6	and	and	CCONJ
aiua-8788	20	7	adjuvant	adjuvant	ADJ
aiua-8788	20	8	chemotherapy	chemotherapy	NOUN
aiua-8788	20	9	represent	represent	VERB
aiua-8788	20	10	the	the	DET
aiua-8788	20	11	gold	gold	ADJ
aiua-8788	20	12	standard	standard	NOUN
aiua-8788	20	13	.	.	PUNCT
aiua-8788	21	1	key	key	ADJ
aiua-8788	21	2	words	word	NOUN
aiua-8788	21	3	:	:	PUNCT
aiua-8788	21	4	neuroendocrine	neuroendocrine	NOUN
aiua-8788	21	5	;	;	PUNCT
aiua-8788	21	6	bladder	bladder	NOUN
aiua-8788	21	7	cancer	cancer	NOUN
aiua-8788	21	8	;	;	PUNCT
aiua-8788	21	9	uro	uro	NOUN
aiua-8788	21	10	-	-	PUNCT
aiua-8788	21	11	oncology	oncology	NOUN
aiua-8788	21	12	;	;	PUNCT
aiua-8788	21	13	rare	rare	ADJ
aiua-8788	21	14	tumors	tumor	NOUN
aiua-8788	21	15	;	;	PUNCT
aiua-8788	21	16	oncology	oncology	NOUN
aiua-8788	21	17	.	.	PUNCT
aiua-8788	21	18	submitted	submit	VERB
aiua-8788	21	19	2	2	NUM
aiua-8788	21	20	march	march	NOUN
aiua-8788	21	21	2020	2020	NUM
aiua-8788	21	22	;	;	PUNCT
aiua-8788	21	23	accepted	accept	VERB
aiua-8788	21	24	15	15	NUM
aiua-8788	21	25	march	march	NOUN
aiua-8788	21	26	2020	2020	NUM
aiua-8788	21	27	summary	summary	NOUN
aiua-8788	21	28	introduction	introduction	NOUN
aiua-8788	21	29	neuroendocrine	neuroendocrine	NOUN
aiua-8788	21	30	tumours	tumours	PROPN
aiua-8788	21	31	(	(	PUNCT
aiua-8788	21	32	net	net	NOUN
aiua-8788	21	33	)	)	PUNCT
aiua-8788	21	34	are	be	AUX
aiua-8788	21	35	extremely	extremely	ADV
aiua-8788	21	36	rare	rare	ADJ
aiua-8788	21	37	(	(	PUNCT
aiua-8788	21	38	1	1	NUM
aiua-8788	21	39	)	)	PUNCT
aiua-8788	21	40	and	and	CCONJ
aiua-8788	21	41	aggressive	aggressive	ADJ
aiua-8788	21	42	.	.	PUNCT
aiua-8788	22	1	it	it	PRON
aiua-8788	22	2	has	have	AUX
aiua-8788	22	3	been	be	AUX
aiua-8788	22	4	valued	value	VERB
aiua-8788	22	5	the	the	DET
aiua-8788	22	6	annual	annual	ADJ
aiua-8788	22	7	incidence	incidence	NOUN
aiua-8788	22	8	is	be	AUX
aiua-8788	22	9	approximately	approximately	ADV
aiua-8788	22	10	2.5	2.5	NUM
aiua-8788	22	11	-	-	SYM
aiua-8788	22	12	5.0	5.0	NUM
aiua-8788	22	13	per	per	ADP
aiua-8788	22	14	100.000	100.000	NUM
aiua-8788	22	15	.	.	PUNCT
aiua-8788	23	1	they	they	PRON
aiua-8788	23	2	take	take	VERB
aiua-8788	23	3	origin	origin	NOUN
aiua-8788	23	4	from	from	ADP
aiua-8788	23	5	cells	cell	NOUN
aiua-8788	23	6	of	of	ADP
aiua-8788	23	7	nervous	nervous	ADJ
aiua-8788	23	8	and	and	CCONJ
aiua-8788	23	9	endocrine	endocrine	NOUN
aiua-8788	23	10	systems	system	NOUN
aiua-8788	23	11	differently	differently	ADV
aiua-8788	23	12	expressed	express	VERB
aiua-8788	23	13	in	in	ADP
aiua-8788	23	14	human	human	ADJ
aiua-8788	23	15	tissues	tissue	NOUN
aiua-8788	23	16	.	.	PUNCT
aiua-8788	24	1	although	although	SCONJ
aiua-8788	24	2	they	they	PRON
aiua-8788	24	3	commonly	commonly	ADV
aiua-8788	24	4	affect	affect	VERB
aiua-8788	24	5	intestine	intestine	NOUN
aiua-8788	24	6	,	,	PUNCT
aiua-8788	24	7	many	many	ADJ
aiua-8788	24	8	organs	organ	NOUN
aiua-8788	24	9	may	may	AUX
aiua-8788	24	10	be	be	AUX
aiua-8788	24	11	involved	involve	VERB
aiua-8788	24	12	such	such	ADJ
aiua-8788	24	13	as	as	ADP
aiua-8788	24	14	pancreas	pancrea	NOUN
aiua-8788	24	15	,	,	PUNCT
aiua-8788	24	16	lung	lung	NOUN
aiua-8788	24	17	or	or	CCONJ
aiua-8788	24	18	urinary	urinary	ADJ
aiua-8788	24	19	tract	tract	NOUN
aiua-8788	24	20	.	.	PUNCT
aiua-8788	25	1	bladder	bladder	NOUN
aiua-8788	25	2	is	be	AUX
aiua-8788	25	3	rarely	rarely	ADV
aiua-8788	25	4	involved	involve	VERB
aiua-8788	25	5	(	(	PUNCT
aiua-8788	25	6	2	2	NUM
aiua-8788	25	7	)	)	PUNCT
aiua-8788	25	8	.	.	PUNCT
aiua-8788	26	1	to	to	PART
aiua-8788	26	2	date	date	VERB
aiua-8788	26	3	two	two	NUM
aiua-8788	26	4	main	main	ADJ
aiua-8788	26	5	forms	form	NOUN
aiua-8788	26	6	of	of	ADP
aiua-8788	26	7	bladder	bladder	NOUN
aiua-8788	26	8	net	net	NOUN
aiua-8788	26	9	have	have	AUX
aiua-8788	26	10	been	be	AUX
aiua-8788	26	11	described	describe	VERB
aiua-8788	26	12	:	:	PUNCT
aiua-8788	26	13	small	small	ADJ
aiua-8788	26	14	-	-	PUNCT
aiua-8788	26	15	cell	cell	NOUN
aiua-8788	26	16	and	and	CCONJ
aiua-8788	26	17	largecell	largecell	NOUN
aiua-8788	26	18	.	.	PUNCT
aiua-8788	27	1	the	the	DET
aiua-8788	27	2	first	first	ADJ
aiua-8788	27	3	one	one	NOUN
aiua-8788	27	4	is	be	AUX
aiua-8788	27	5	considered	consider	VERB
aiua-8788	27	6	highly	highly	ADV
aiua-8788	27	7	aggressive	aggressive	ADJ
aiua-8788	27	8	since	since	SCONJ
aiua-8788	27	9	it	it	PRON
aiua-8788	27	10	shows	show	VERB
aiua-8788	27	11	poor	poor	ADJ
aiua-8788	27	12	oncologic	oncologic	ADJ
aiua-8788	27	13	outcomes	outcome	NOUN
aiua-8788	27	14	being	be	AUX
aiua-8788	27	15	mainly	mainly	ADV
aiua-8788	27	16	diagnosed	diagnose	VERB
aiua-8788	27	17	at	at	ADP
aiua-8788	27	18	advanced	advanced	ADJ
aiua-8788	27	19	stage	stage	NOUN
aiua-8788	27	20	:	:	PUNCT
aiua-8788	27	21	the	the	DET
aiua-8788	27	22	second	second	ADJ
aiua-8788	27	23	one	one	NOUN
aiua-8788	27	24	is	be	AUX
aiua-8788	27	25	extremely	extremely	ADV
aiua-8788	27	26	rare	rare	ADJ
aiua-8788	27	27	and	and	CCONJ
aiua-8788	27	28	equally	equally	ADV
aiua-8788	27	29	aggressive	aggressive	ADJ
aiua-8788	27	30	.	.	PUNCT
aiua-8788	28	1	data	datum	NOUN
aiua-8788	28	2	in	in	ADP
aiua-8788	28	3	literature	literature	NOUN
aiua-8788	28	4	are	be	AUX
aiua-8788	28	5	strongly	strongly	ADV
aiua-8788	28	6	limited	limited	ADJ
aiua-8788	28	7	.	.	PUNCT
aiua-8788	29	1	here	here	ADV
aiua-8788	29	2	we	we	PRON
aiua-8788	29	3	report	report	VERB
aiua-8788	29	4	the	the	DET
aiua-8788	29	5	case	case	NOUN
aiua-8788	29	6	of	of	ADP
aiua-8788	29	7	a	a	DET
aiua-8788	29	8	small	small	ADJ
aiua-8788	29	9	-	-	PUNCT
aiua-8788	29	10	cell	cell	NOUN
aiua-8788	29	11	neuroendocrine	neuroendocrine	ADJ
aiua-8788	29	12	carcinoma	carcinoma	NOUN
aiua-8788	29	13	of	of	ADP
aiua-8788	29	14	urinary	urinary	ADJ
aiua-8788	29	15	bladder	bladder	NOUN
aiua-8788	29	16	.	.	PUNCT
aiua-8788	30	1	while	while	SCONJ
aiua-8788	30	2	opportunely	opportunely	ADV
aiua-8788	30	3	describing	describe	VERB
aiua-8788	30	4	this	this	DET
aiua-8788	30	5	case	case	NOUN
aiua-8788	30	6	,	,	PUNCT
aiua-8788	30	7	we	we	PRON
aiua-8788	30	8	also	also	ADV
aiua-8788	30	9	reviewed	review	VERB
aiua-8788	30	10	the	the	DET
aiua-8788	30	11	literature	literature	NOUN
aiua-8788	30	12	on	on	ADP
aiua-8788	30	13	pubmed	pubmed	PROPN
aiua-8788	30	14	about	about	ADP
aiua-8788	30	15	this	this	DET
aiua-8788	30	16	pathological	pathological	ADJ
aiua-8788	30	17	condition	condition	NOUN
aiua-8788	30	18	.	.	PUNCT
aiua-8788	31	1	case	case	NOUN
aiua-8788	31	2	report	report	VERB
aiua-8788	31	3	a	a	DET
aiua-8788	31	4	78	78	NUM
aiua-8788	31	5	-	-	PUNCT
aiua-8788	31	6	years	year	NOUN
aiua-8788	31	7	-	-	PUNCT
aiua-8788	31	8	old	old	ADJ
aiua-8788	31	9	caucasian	caucasian	ADJ
aiua-8788	31	10	male	male	NOUN
aiua-8788	31	11	presented	present	VERB
aiua-8788	31	12	to	to	ADP
aiua-8788	31	13	our	our	PRON
aiua-8788	31	14	facility	facility	NOUN
aiua-8788	31	15	for	for	ADP
aiua-8788	31	16	lower	low	ADJ
aiua-8788	31	17	urinary	urinary	ADJ
aiua-8788	31	18	tract	tract	NOUN
aiua-8788	31	19	symptoms	symptom	NOUN
aiua-8788	31	20	and	and	CCONJ
aiua-8788	31	21	gross	gross	ADJ
aiua-8788	31	22	hematuria	hematuria	NOUN
aiua-8788	31	23	recently	recently	ADV
aiua-8788	31	24	occurred	occur	VERB
aiua-8788	31	25	.	.	PUNCT
aiua-8788	32	1	he	he	PRON
aiua-8788	32	2	was	be	AUX
aiua-8788	32	3	a	a	DET
aiua-8788	32	4	strong	strong	ADJ
aiua-8788	32	5	smoker	smoker	NOUN
aiua-8788	32	6	since	since	SCONJ
aiua-8788	32	7	many	many	ADJ
aiua-8788	32	8	years	year	NOUN
aiua-8788	32	9	.	.	PUNCT
aiua-8788	33	1	no	no	DET
aiua-8788	33	2	familiarity	familiarity	NOUN
aiua-8788	33	3	for	for	ADP
aiua-8788	33	4	urothelial	urothelial	ADJ
aiua-8788	33	5	cancer	cancer	NOUN
aiua-8788	33	6	was	be	AUX
aiua-8788	33	7	referred	refer	VERB
aiua-8788	33	8	nor	nor	CCONJ
aiua-8788	33	9	previous	previous	ADJ
aiua-8788	33	10	episodes	episode	NOUN
aiua-8788	33	11	of	of	ADP
aiua-8788	33	12	haematuria	haematuria	NOUN
aiua-8788	33	13	until	until	ADP
aiua-8788	33	14	that	that	DET
aiua-8788	33	15	time	time	NOUN
aiua-8788	33	16	.	.	PUNCT
aiua-8788	34	1	on	on	ADP
aiua-8788	34	2	past	past	ADJ
aiua-8788	34	3	anamnesis	anamnesis	NOUN
aiua-8788	34	4	he	he	PRON
aiua-8788	34	5	suffered	suffer	VERB
aiua-8788	34	6	from	from	ADP
aiua-8788	34	7	myocardial	myocardial	ADJ
aiua-8788	34	8	infarction	infarction	NOUN
aiua-8788	34	9	and	and	CCONJ
aiua-8788	34	10	chronic	chronic	ADJ
aiua-8788	34	11	fibrillation	fibrillation	NOUN
aiua-8788	34	12	being	be	AUX
aiua-8788	34	13	actually	actually	ADV
aiua-8788	34	14	on	on	ADP
aiua-8788	34	15	medication	medication	NOUN
aiua-8788	34	16	with	with	ADP
aiua-8788	34	17	acetilsalicilate	acetilsalicilate	NOUN
aiua-8788	34	18	plus	plus	CCONJ
aiua-8788	34	19	edoxaban	edoxaban	NOUN
aiua-8788	34	20	.	.	PUNCT
aiua-8788	35	1	multiple	multiple	ADJ
aiua-8788	35	2	coexisting	coexist	VERB
aiua-8788	35	3	systemic	systemic	ADJ
aiua-8788	35	4	illness	illness	NOUN
aiua-8788	35	5	were	be	AUX
aiua-8788	35	6	reported	report	VERB
aiua-8788	35	7	such	such	ADJ
aiua-8788	35	8	as	as	ADP
aiua-8788	35	9	hypertension	hypertension	NOUN
aiua-8788	35	10	,	,	PUNCT
aiua-8788	35	11	dyslipidemia	dyslipidemia	NOUN
aiua-8788	35	12	and	and	CCONJ
aiua-8788	35	13	mild	mild	ADJ
aiua-8788	35	14	chronic	chronic	ADJ
aiua-8788	35	15	renal	renal	ADJ
aiua-8788	35	16	failure	failure	NOUN
aiua-8788	35	17	.	.	PUNCT
aiua-8788	36	1	furthermore	furthermore	ADV
aiua-8788	36	2	,	,	PUNCT
aiua-8788	36	3	he	he	PRON
aiua-8788	36	4	was	be	AUX
aiua-8788	36	5	also	also	ADV
aiua-8788	36	6	on	on	ADP
aiua-8788	36	7	medication	medication	NOUN
aiua-8788	36	8	with	with	ADP
aiua-8788	36	9	adrenergic	adrenergic	ADJ
aiua-8788	36	10	a1	a1	NOUN
aiua-8788	36	11	-	-	PUNCT
aiua-8788	36	12	antagonist	antagonist	NOUN
aiua-8788	36	13	for	for	ADP
aiua-8788	36	14	a	a	DET
aiua-8788	36	15	benign	benign	ADJ
aiua-8788	36	16	prostatic	prostatic	ADJ
aiua-8788	36	17	hyperplasia	hyperplasia	NOUN
aiua-8788	36	18	(	(	PUNCT
aiua-8788	36	19	bph	bph	NOUN
aiua-8788	36	20	)	)	PUNCT
aiua-8788	36	21	condition	condition	NOUN
aiua-8788	36	22	:	:	PUNCT
aiua-8788	36	23	anyway	anyway	ADV
aiua-8788	36	24	,	,	PUNCT
aiua-8788	36	25	his	his	PRON
aiua-8788	36	26	last	last	ADJ
aiua-8788	36	27	psa	psa	NOUN
aiua-8788	36	28	was	be	AUX
aiua-8788	36	29	normal	normal	ADJ
aiua-8788	36	30	and	and	CCONJ
aiua-8788	36	31	digito	digito	ADJ
aiua-8788	36	32	-	-	ADJ
aiua-8788	36	33	rectal	rectal	ADJ
aiua-8788	36	34	exploration	exploration	NOUN
aiua-8788	36	35	confirmed	confirm	VERB
aiua-8788	36	36	an	an	DET
aiua-8788	36	37	enlarged	enlarged	ADJ
aiua-8788	36	38	soft	soft	ADJ
aiua-8788	36	39	gland	gland	NOUN
aiua-8788	36	40	.	.	PUNCT
aiua-8788	37	1	general	general	ADJ
aiua-8788	37	2	and	and	CCONJ
aiua-8788	37	3	systemic	systemic	ADJ
aiua-8788	37	4	examination	examination	NOUN
aiua-8788	37	5	was	be	AUX
aiua-8788	37	6	unremarkable	unremarkable	ADJ
aiua-8788	37	7	:	:	PUNCT
aiua-8788	37	8	no	no	DET
aiua-8788	37	9	asthenia	asthenia	NOUN
aiua-8788	37	10	,	,	PUNCT
aiua-8788	37	11	weight	weight	NOUN
aiua-8788	37	12	loss	loss	NOUN
aiua-8788	37	13	,	,	PUNCT
aiua-8788	37	14	abdominal	abdominal	ADJ
aiua-8788	37	15	palpable	palpable	ADJ
aiua-8788	37	16	masses	masse	NOUN
aiua-8788	37	17	or	or	CCONJ
aiua-8788	37	18	acute	acute	ADJ
aiua-8788	37	19	urinary	urinary	ADJ
aiua-8788	37	20	retention	retention	NOUN
aiua-8788	37	21	were	be	AUX
aiua-8788	37	22	present	present	ADJ
aiua-8788	37	23	.	.	PUNCT
aiua-8788	38	1	blood	blood	NOUN
aiua-8788	38	2	examination	examination	NOUN
aiua-8788	38	3	revealed	reveal	VERB
aiua-8788	38	4	a	a	DET
aiua-8788	38	5	mild	mild	ADJ
aiua-8788	38	6	anaemia	anaemia	NOUN
aiua-8788	38	7	while	while	SCONJ
aiua-8788	38	8	renal	renal	ADJ
aiua-8788	38	9	function	function	NOUN
aiua-8788	38	10	and	and	CCONJ
aiua-8788	38	11	white	white	ADJ
aiua-8788	38	12	blood	blood	NOUN
aiua-8788	38	13	count	count	NOUN
aiua-8788	38	14	were	be	AUX
aiua-8788	38	15	unremarkable	unremarkable	ADJ
aiua-8788	38	16	.	.	PUNCT
aiua-8788	39	1	urinalysis	urinalysis	NOUN
aiua-8788	39	2	confirmed	confirm	VERB
aiua-8788	39	3	haematuria	haematuria	PROPN
aiua-8788	39	4	but	but	CCONJ
aiua-8788	39	5	cytology	cytology	NOUN
aiua-8788	39	6	was	be	AUX
aiua-8788	39	7	negative	negative	ADJ
aiua-8788	39	8	.	.	PUNCT
aiua-8788	40	1	ambulatory	ambulatory	ADJ
aiua-8788	40	2	ultrasound	ultrasound	NOUN
aiua-8788	40	3	revealed	reveal	VERB
aiua-8788	40	4	a	a	DET
aiua-8788	40	5	3	3	NUM
aiua-8788	40	6	cm	cm	NOUN
aiua-8788	40	7	bladder	bladder	NOUN
aiua-8788	40	8	wall	wall	NOUN
aiua-8788	40	9	thickening	thicken	VERB
aiua-8788	40	10	highly	highly	ADV
aiua-8788	40	11	suspicious	suspicious	ADJ
aiua-8788	40	12	for	for	ADP
aiua-8788	40	13	bladder	bladder	NOUN
aiua-8788	40	14	cancer	cancer	NOUN
aiua-8788	40	15	;	;	PUNCT
aiua-8788	40	16	the	the	DET
aiua-8788	40	17	patient	patient	NOUN
aiua-8788	40	18	subsequently	subsequently	ADV
aiua-8788	40	19	underwent	undergo	VERB
aiua-8788	40	20	to	to	PART
aiua-8788	40	21	contrastenhanced	contrastenhance	VERB
aiua-8788	40	22	ct	ct	PROPN
aiua-8788	40	23	.	.	PUNCT
aiua-8788	41	1	the	the	DET
aiua-8788	41	2	examination	examination	NOUN
aiua-8788	41	3	confirmed	confirm	VERB
aiua-8788	41	4	the	the	DET
aiua-8788	41	5	bladder	bladder	NOUN
aiua-8788	41	6	lesion	lesion	NOUN
aiua-8788	41	7	(	(	PUNCT
aiua-8788	41	8	figure	figure	NOUN
aiua-8788	41	9	1	1	NUM
aiua-8788	41	10	)	)	PUNCT
aiua-8788	41	11	totally	totally	ADV
aiua-8788	41	12	excluding	exclude	VERB
aiua-8788	41	13	bilateral	bilateral	ADJ
aiua-8788	41	14	hydronephrosis	hydronephrosis	NOUN
aiua-8788	41	15	,	,	PUNCT
aiua-8788	41	16	visceral	visceral	ADJ
aiua-8788	41	17	metastases	metastasis	NOUN
aiua-8788	41	18	or	or	CCONJ
aiua-8788	41	19	lymph	lymph	NOUN
aiua-8788	41	20	nodes	node	NOUN
aiua-8788	41	21	involvement	involvement	NOUN
aiua-8788	41	22	.	.	PUNCT
aiua-8788	42	1	a	a	DET
aiua-8788	42	2	trans	trans	PROPN
aiua-8788	42	3	urethral	urethral	ADJ
aiua-8788	42	4	resection	resection	NOUN
aiua-8788	42	5	(	(	PUNCT
aiua-8788	42	6	turb	turb	NOUN
aiua-8788	42	7	)	)	PUNCT
aiua-8788	42	8	of	of	ADP
aiua-8788	42	9	the	the	DET
aiua-8788	42	10	mass	mass	NOUN
aiua-8788	42	11	was	be	AUX
aiua-8788	42	12	offered	offer	VERB
aiua-8788	42	13	.	.	PUNCT
aiua-8788	43	1	pathology	pathology	NOUN
aiua-8788	43	2	report	report	NOUN
aiua-8788	43	3	revealed	reveal	VERB
aiua-8788	43	4	a	a	DET
aiua-8788	43	5	mixed	mixed	ADJ
aiua-8788	43	6	bladder	bladder	NOUN
aiua-8788	43	7	tumour	tumour	NOUN
aiua-8788	43	8	:	:	PUNCT
aiua-8788	43	9	30	30	NUM
aiua-8788	43	10	%	%	NOUN
aiua-8788	43	11	of	of	ADP
aiua-8788	43	12	specimen	speciman	NOUN
aiua-8788	43	13	resulted	result	VERB
aiua-8788	43	14	as	as	ADP
aiua-8788	43	15	an	an	DET
aiua-8788	43	16	high	high	ADJ
aiua-8788	43	17	-	-	PUNCT
aiua-8788	43	18	grade	grade	NOUN
aiua-8788	43	19	urothelial	urothelial	ADJ
aiua-8788	43	20	cancer	cancer	NOUN
aiua-8788	43	21	(	(	PUNCT
aiua-8788	43	22	g3	g3	NOUN
aiua-8788	43	23	)	)	PUNCT
aiua-8788	43	24	while	while	SCONJ
aiua-8788	43	25	70	70	NUM
aiua-8788	43	26	%	%	NOUN
aiua-8788	43	27	as	as	ADP
aiua-8788	43	28	small	small	ADJ
aiua-8788	43	29	-	-	PUNCT
aiua-8788	43	30	cell	cell	NOUN
aiua-8788	43	31	neuroendocrine	neuroendocrine	ADJ
aiua-8788	43	32	variant	variant	NOUN
aiua-8788	43	33	(	(	PUNCT
aiua-8788	43	34	figure	figure	NOUN
aiua-8788	43	35	2	2	NUM
aiua-8788	43	36	)	)	PUNCT
aiua-8788	43	37	.	.	PUNCT
aiua-8788	44	1	microscopic	microscopic	ADJ
aiua-8788	44	2	muscle	muscle	NOUN
aiua-8788	44	3	involvement	involvement	NOUN
aiua-8788	44	4	was	be	AUX
aiua-8788	44	5	excluded	exclude	VERB
aiua-8788	44	6	.	.	PUNCT
aiua-8788	45	1	in	in	ADP
aiua-8788	45	2	order	order	NOUN
aiua-8788	45	3	to	to	PART
aiua-8788	45	4	better	well	ADV
aiua-8788	45	5	characterize	characterize	VERB
aiua-8788	45	6	the	the	DET
aiua-8788	45	7	neuroendocrine	neuroendocrine	ADJ
aiua-8788	45	8	differentiation	differentiation	NOUN
aiua-8788	45	9	,	,	PUNCT
aiua-8788	45	10	further	further	ADJ
aiua-8788	45	11	evaluation	evaluation	NOUN
aiua-8788	45	12	using	use	VERB
aiua-8788	45	13	immunohistochemistry	immunohistochemistry	NOUN
aiua-8788	45	14	was	be	AUX
aiua-8788	45	15	mandatory	mandatory	ADJ
aiua-8788	45	16	:	:	PUNCT
aiua-8788	45	17	cytokeratin	cytokeratin	NOUN
aiua-8788	45	18	,	,	PUNCT
aiua-8788	45	19	synaptophysin	synaptophysin	NOUN
aiua-8788	45	20	and	and	CCONJ
aiua-8788	45	21	14corongiu1_stesura	14corongiu1_stesura	NUM
aiua-8788	45	22	seveso	seveso	NOUN
aiua-8788	45	23	25/09/20	25/09/20	PROPN
aiua-8788	45	24	13:12	13:12	NUM
aiua-8788	45	25	pagina	pagina	NOUN
aiua-8788	45	26	211	211	NUM
aiua-8788	45	27	archivio	archivio	NOUN
aiua-8788	45	28	italiano	italiano	NOUN
aiua-8788	45	29	di	di	X
aiua-8788	45	30	urologia	urologia	PROPN
aiua-8788	45	31	e	e	PROPN
aiua-8788	45	32	andrologia	andrologia	NOUN
aiua-8788	45	33	2020	2020	NUM
aiua-8788	45	34	;	;	PUNCT
aiua-8788	45	35	92	92	NUM
aiua-8788	45	36	,	,	PUNCT
aiua-8788	45	37	3	3	NUM
aiua-8788	45	38	v.	v.	ADP
aiua-8788	45	39	olivieri	olivieri	PROPN
aiua-8788	45	40	,	,	PUNCT
aiua-8788	45	41	v.	v.	ADP
aiua-8788	45	42	fortunati	fortunati	PROPN
aiua-8788	45	43	,	,	PUNCT
aiua-8788	45	44	l.	l.	NOUN
aiua-8788	45	45	bellei	bellei	PROPN
aiua-8788	45	46	,	,	PUNCT
aiua-8788	45	47	m.	m.	NOUN
aiua-8788	45	48	massarelli	massarelli	PROPN
aiua-8788	45	49	,	,	PUNCT
aiua-8788	45	50	g.	g.	PROPN
aiua-8788	45	51	ruggiero	ruggiero	PROPN
aiua-8788	45	52	,	,	PUNCT
aiua-8788	45	53	d.	d.	PROPN
aiua-8788	45	54	abate	abate	VERB
aiua-8788	45	55	,	,	PUNCT
aiua-8788	45	56	n.	n.	PROPN
aiua-8788	45	57	serra	serra	PROPN
aiua-8788	45	58	,	,	PUNCT
aiua-8788	45	59	d.	d.	PROPN
aiua-8788	45	60	griffa	griffa	PROPN
aiua-8788	45	61	,	,	PUNCT
aiua-8788	45	62	f.	f.	PROPN
aiua-8788	45	63	forte	forte	PROPN
aiua-8788	45	64	,	,	PUNCT
aiua-8788	45	65	e.	e.	PROPN
aiua-8788	45	66	corongiu	corongiu	PROPN
aiua-8788	45	67	212	212	NUM
aiua-8788	45	68	ki-67	ki-67	NUM
aiua-8788	45	69	were	be	AUX
aiua-8788	45	70	used	use	VERB
aiua-8788	45	71	as	as	ADP
aiua-8788	45	72	molecular	molecular	ADJ
aiua-8788	45	73	markers	marker	NOUN
aiua-8788	45	74	.	.	PUNCT
aiua-8788	46	1	urothelial	urothelial	ADJ
aiua-8788	46	2	histotype	histotype	NOUN
aiua-8788	46	3	resulted	result	VERB
aiua-8788	46	4	positive	positive	ADJ
aiua-8788	46	5	for	for	ADP
aiua-8788	46	6	cytokeratine	cytokeratine	ADJ
aiua-8788	46	7	but	but	CCONJ
aiua-8788	46	8	negative	negative	ADJ
aiua-8788	46	9	for	for	ADP
aiua-8788	46	10	synaptophysin	synaptophysin	NOUN
aiua-8788	46	11	while	while	SCONJ
aiua-8788	46	12	the	the	DET
aiua-8788	46	13	neuroendocrine	neuroendocrine	ADJ
aiua-8788	46	14	variant	variant	NOUN
aiua-8788	46	15	was	be	AUX
aiua-8788	46	16	positive	positive	ADJ
aiua-8788	46	17	for	for	ADP
aiua-8788	46	18	both	both	PRON
aiua-8788	46	19	of	of	ADP
aiua-8788	46	20	them	they	PRON
aiua-8788	46	21	.	.	PUNCT
aiua-8788	47	1	ki-67	ki-67	PRON
aiua-8788	47	2	,	,	PUNCT
aiua-8788	47	3	a	a	DET
aiua-8788	47	4	molecular	molecular	ADJ
aiua-8788	47	5	marker	marker	NOUN
aiua-8788	47	6	as	as	ADP
aiua-8788	47	7	expression	expression	NOUN
aiua-8788	47	8	of	of	ADP
aiua-8788	47	9	proliferation	proliferation	NOUN
aiua-8788	47	10	rate	rate	NOUN
aiua-8788	47	11	,	,	PUNCT
aiua-8788	47	12	was	be	AUX
aiua-8788	47	13	90	90	NUM
aiua-8788	47	14	%	%	NOUN
aiua-8788	47	15	totally	totally	ADV
aiua-8788	47	16	suggesting	suggest	VERB
aiua-8788	47	17	an	an	DET
aiua-8788	47	18	aggressive	aggressive	ADJ
aiua-8788	47	19	bladder	bladder	NOUN
aiua-8788	47	20	cancer	cancer	NOUN
aiua-8788	47	21	,	,	PUNCT
aiua-8788	47	22	in	in	ADP
aiua-8788	47	23	fact	fact	NOUN
aiua-8788	47	24	net	net	NOUN
aiua-8788	47	25	are	be	AUX
aiua-8788	47	26	histologically	histologically	ADV
aiua-8788	47	27	graded	grade	VERB
aiua-8788	47	28	according	accord	VERB
aiua-8788	47	29	to	to	ADP
aiua-8788	47	30	mitotic	mitotic	ADJ
aiua-8788	47	31	count	count	NOUN
aiua-8788	47	32	and	and	CCONJ
aiua-8788	47	33	markers	marker	NOUN
aiua-8788	47	34	of	of	ADP
aiua-8788	47	35	cellular	cellular	ADJ
aiua-8788	47	36	proliferation	proliferation	NOUN
aiua-8788	47	37	(	(	PUNCT
aiua-8788	47	38	ki-67	ki-67	X
aiua-8788	47	39	index	index	NOUN
aiua-8788	47	40	)	)	PUNCT
aiua-8788	47	41	rather	rather	ADV
aiua-8788	47	42	than	than	ADP
aiua-8788	47	43	cellular	cellular	ADJ
aiua-8788	47	44	polymorphism	polymorphism	NOUN
aiua-8788	47	45	:	:	PUNCT
aiua-8788	47	46	a	a	DET
aiua-8788	47	47	mitotic	mitotic	ADJ
aiua-8788	47	48	count	count	NOUN
aiua-8788	47	49	>	>	X
aiua-8788	47	50	20	20	NUM
aiua-8788	47	51	per	per	ADP
aiua-8788	47	52	10	10	NUM
aiua-8788	47	53	hpf	hpf	NOUN
aiua-8788	47	54	and	and	CCONJ
aiua-8788	47	55	a	a	DET
aiua-8788	47	56	ki-67	ki-67	ADJ
aiua-8788	47	57	index	index	NOUN
aiua-8788	47	58	>	>	SYM
aiua-8788	47	59	20	20	NUM
aiua-8788	47	60	%	%	NOUN
aiua-8788	47	61	defines	define	VERB
aiua-8788	47	62	the	the	DET
aiua-8788	47	63	high	high	ADJ
aiua-8788	47	64	-	-	PUNCT
aiua-8788	47	65	grade	grade	NOUN
aiua-8788	47	66	.	.	PUNCT
aiua-8788	48	1	due	due	ADP
aiua-8788	48	2	to	to	ADP
aiua-8788	48	3	its	its	PRON
aiua-8788	48	4	non	non	ADJ
aiua-8788	48	5	-	-	ADJ
aiua-8788	48	6	urothelial	urothelial	ADJ
aiua-8788	48	7	origins	origin	NOUN
aiua-8788	48	8	,	,	PUNCT
aiua-8788	48	9	it	it	PRON
aiua-8788	48	10	was	be	AUX
aiua-8788	48	11	also	also	ADV
aiua-8788	48	12	classified	classify	VERB
aiua-8788	48	13	as	as	ADP
aiua-8788	48	14	a	a	DET
aiua-8788	48	15	highest	high	ADJ
aiua-8788	48	16	risk	risk	NOUN
aiua-8788	48	17	tumour	tumour	NOUN
aiua-8788	48	18	.	.	PUNCT
aiua-8788	49	1	treatments	treatment	NOUN
aiua-8788	49	2	,	,	PUNCT
aiua-8788	49	3	in	in	ADP
aiua-8788	49	4	these	these	DET
aiua-8788	49	5	cases	case	NOUN
aiua-8788	49	6	,	,	PUNCT
aiua-8788	49	7	depends	depend	VERB
aiua-8788	49	8	on	on	ADP
aiua-8788	49	9	many	many	ADJ
aiua-8788	49	10	factors	factor	NOUN
aiua-8788	49	11	;	;	PUNCT
aiua-8788	49	12	several	several	ADJ
aiua-8788	49	13	issues	issue	NOUN
aiua-8788	49	14	such	such	ADJ
aiua-8788	49	15	as	as	ADP
aiua-8788	49	16	anatomic	anatomic	ADJ
aiua-8788	49	17	location	location	NOUN
aiua-8788	49	18	,	,	PUNCT
aiua-8788	49	19	tumour	tumour	NOUN
aiua-8788	49	20	differentiation	differentiation	NOUN
aiua-8788	49	21	,	,	PUNCT
aiua-8788	49	22	staging	staging	NOUN
aiua-8788	49	23	,	,	PUNCT
aiua-8788	49	24	metastases	metastasis	NOUN
aiua-8788	49	25	,	,	PUNCT
aiua-8788	49	26	lymph	lymph	NOUN
aiua-8788	49	27	node	node	NOUN
aiua-8788	49	28	involvement	involvement	NOUN
aiua-8788	49	29	and	and	CCONJ
aiua-8788	49	30	symptoms	symptom	NOUN
aiua-8788	49	31	may	may	AUX
aiua-8788	49	32	help	help	VERB
aiua-8788	49	33	to	to	PART
aiua-8788	49	34	define	define	VERB
aiua-8788	49	35	the	the	DET
aiua-8788	49	36	best	good	ADJ
aiua-8788	49	37	therapeutic	therapeutic	ADJ
aiua-8788	49	38	approach	approach	NOUN
aiua-8788	49	39	.	.	PUNCT
aiua-8788	50	1	the	the	DET
aiua-8788	50	2	high	high	ADJ
aiua-8788	50	3	-	-	PUNCT
aiua-8788	50	4	grade	grade	NOUN
aiua-8788	50	5	forms	form	NOUN
aiua-8788	50	6	should	should	AUX
aiua-8788	50	7	be	be	AUX
aiua-8788	50	8	managed	manage	VERB
aiua-8788	50	9	by	by	ADP
aiua-8788	50	10	active	active	ADJ
aiua-8788	50	11	treatment	treatment	NOUN
aiua-8788	50	12	which	which	PRON
aiua-8788	50	13	may	may	AUX
aiua-8788	50	14	be	be	AUX
aiua-8788	50	15	multimodal	multimodal	ADJ
aiua-8788	50	16	.	.	PUNCT
aiua-8788	51	1	unless	unless	SCONJ
aiua-8788	51	2	metastatic	metastatic	ADJ
aiua-8788	51	3	,	,	PUNCT
aiua-8788	51	4	radical	radical	ADJ
aiua-8788	51	5	cystectomy	cystectomy	NOUN
aiua-8788	51	6	and	and	CCONJ
aiua-8788	51	7	chemotherapy	chemotherapy	NOUN
aiua-8788	51	8	(	(	PUNCT
aiua-8788	51	9	either	either	CCONJ
aiua-8788	51	10	neoadjuvant	neoadjuvant	ADJ
aiua-8788	51	11	or	or	CCONJ
aiua-8788	51	12	adjuvant	adjuvant	ADJ
aiua-8788	51	13	)	)	PUNCT
aiua-8788	51	14	must	must	AUX
aiua-8788	51	15	be	be	AUX
aiua-8788	51	16	offered	offer	VERB
aiua-8788	51	17	(	(	PUNCT
aiua-8788	51	18	3	3	NUM
aiua-8788	51	19	)	)	PUNCT
aiua-8788	51	20	since	since	SCONJ
aiua-8788	51	21	turb	turb	PROPN
aiua-8788	51	22	alone	alone	ADV
aiua-8788	51	23	seems	seem	VERB
aiua-8788	51	24	to	to	PART
aiua-8788	51	25	be	be	AUX
aiua-8788	51	26	an	an	DET
aiua-8788	51	27	inadequate	inadequate	ADJ
aiua-8788	51	28	method	method	NOUN
aiua-8788	51	29	of	of	ADP
aiua-8788	51	30	disease	disease	NOUN
aiua-8788	51	31	control	control	NOUN
aiua-8788	51	32	.	.	PUNCT
aiua-8788	52	1	recently	recently	ADV
aiua-8788	52	2	,	,	PUNCT
aiua-8788	52	3	some	some	DET
aiua-8788	52	4	authors	author	NOUN
aiua-8788	52	5	noted	note	VERB
aiua-8788	52	6	molecular	molecular	ADJ
aiua-8788	52	7	abnormalities	abnormality	NOUN
aiua-8788	52	8	in	in	ADP
aiua-8788	52	9	small	small	ADJ
aiua-8788	52	10	cell	cell	NOUN
aiua-8788	52	11	neuroendocrine	neuroendocrine	NOUN
aiua-8788	52	12	bladder	bladder	NOUN
aiua-8788	52	13	cancer	cancer	NOUN
aiua-8788	52	14	also	also	ADV
aiua-8788	52	15	raising	raise	VERB
aiua-8788	52	16	the	the	DET
aiua-8788	52	17	question	question	NOUN
aiua-8788	52	18	of	of	ADP
aiua-8788	52	19	using	use	VERB
aiua-8788	52	20	target	target	NOUN
aiua-8788	52	21	therapies	therapy	NOUN
aiua-8788	52	22	:	:	PUNCT
aiua-8788	52	23	targeting	target	VERB
aiua-8788	52	24	angiogenesis	angiogenesis	NOUN
aiua-8788	52	25	would	would	AUX
aiua-8788	52	26	be	be	AUX
aiua-8788	52	27	the	the	DET
aiua-8788	52	28	most	most	ADV
aiua-8788	52	29	promising	promising	ADJ
aiua-8788	52	30	.	.	PUNCT
aiua-8788	53	1	anyway	anyway	ADV
aiua-8788	53	2	,	,	PUNCT
aiua-8788	53	3	to	to	ADP
aiua-8788	53	4	date	date	NOUN
aiua-8788	53	5	immunotherapy	immunotherapy	NOUN
aiua-8788	53	6	still	still	ADV
aiua-8788	53	7	remains	remain	VERB
aiua-8788	53	8	under	under	ADP
aiua-8788	53	9	debate	debate	NOUN
aiua-8788	53	10	.	.	PUNCT
aiua-8788	54	1	in	in	ADP
aiua-8788	54	2	our	our	PRON
aiua-8788	54	3	case	case	NOUN
aiua-8788	54	4	,	,	PUNCT
aiua-8788	54	5	we	we	PRON
aiua-8788	54	6	evaluated	evaluate	VERB
aiua-8788	54	7	the	the	DET
aiua-8788	54	8	patient	patient	NOUN
aiua-8788	54	9	in	in	ADP
aiua-8788	54	10	a	a	DET
aiua-8788	54	11	multidisciplinary	multidisciplinary	ADJ
aiua-8788	54	12	tumour	tumour	NOUN
aiua-8788	54	13	board	board	NOUN
aiua-8788	54	14	in	in	ADP
aiua-8788	54	15	order	order	NOUN
aiua-8788	54	16	to	to	PART
aiua-8788	54	17	offer	offer	VERB
aiua-8788	54	18	the	the	DET
aiua-8788	54	19	best	good	ADJ
aiua-8788	54	20	disease	disease	NOUN
aiua-8788	54	21	management	management	NOUN
aiua-8788	54	22	.	.	PUNCT
aiua-8788	55	1	according	accord	VERB
aiua-8788	55	2	to	to	ADP
aiua-8788	55	3	karnofsky	karnofsky	ADJ
aiua-8788	55	4	performance	performance	NOUN
aiua-8788	55	5	status	status	NOUN
aiua-8788	55	6	,	,	PUNCT
aiua-8788	55	7	comorbidities	comorbiditie	NOUN
aiua-8788	55	8	and	and	CCONJ
aiua-8788	55	9	iatrogenic	iatrogenic	ADJ
aiua-8788	55	10	bleeding	bleeding	NOUN
aiua-8788	55	11	risk	risk	NOUN
aiua-8788	55	12	,	,	PUNCT
aiua-8788	55	13	adjuvant	adjuvant	ADJ
aiua-8788	55	14	chemotherapy	chemotherapy	NOUN
aiua-8788	55	15	and	and	CCONJ
aiua-8788	55	16	radiation	radiation	NOUN
aiua-8788	55	17	were	be	AUX
aiua-8788	55	18	not	not	PART
aiua-8788	55	19	suggested	suggest	VERB
aiua-8788	55	20	:	:	PUNCT
aiua-8788	55	21	radical	radical	ADJ
aiua-8788	55	22	cystectomy	cystectomy	NOUN
aiua-8788	55	23	was	be	AUX
aiua-8788	55	24	also	also	ADV
aiua-8788	55	25	offered	offer	VERB
aiua-8788	55	26	but	but	CCONJ
aiua-8788	55	27	patient	patient	NOUN
aiua-8788	55	28	refused	refuse	VERB
aiua-8788	55	29	that	that	DET
aiua-8788	55	30	option	option	NOUN
aiua-8788	55	31	.	.	PUNCT
aiua-8788	56	1	he	he	PRON
aiua-8788	56	2	simply	simply	ADV
aiua-8788	56	3	underwent	undergo	VERB
aiua-8788	56	4	follow	follow	VERB
aiua-8788	56	5	up	up	ADP
aiua-8788	56	6	.	.	PUNCT
aiua-8788	57	1	after	after	ADP
aiua-8788	57	2	3	3	NUM
aiua-8788	57	3	months	month	NOUN
aiua-8788	57	4	total	total	ADJ
aiua-8788	57	5	body	body	NOUN
aiua-8788	57	6	tc	tc	NOUN
aiua-8788	57	7	showed	show	VERB
aiua-8788	57	8	multiple	multiple	ADJ
aiua-8788	57	9	visceral	visceral	ADJ
aiua-8788	57	10	metastases	metastasis	NOUN
aiua-8788	57	11	(	(	PUNCT
aiua-8788	57	12	figures	figure	NOUN
aiua-8788	57	13	3	3	NUM
aiua-8788	57	14	-	-	SYM
aiua-8788	57	15	4	4	NUM
aiua-8788	57	16	)	)	PUNCT
aiua-8788	57	17	also	also	ADV
aiua-8788	57	18	involving	involve	VERB
aiua-8788	57	19	brain	brain	NOUN
aiua-8788	57	20	and	and	CCONJ
aiua-8788	57	21	lymph	lymph	NOUN
aiua-8788	57	22	nodes	node	NOUN
aiua-8788	57	23	:	:	PUNCT
aiua-8788	57	24	best	good	ADJ
aiua-8788	57	25	supportive	supportive	ADJ
aiua-8788	57	26	care	care	NOUN
aiua-8788	57	27	was	be	AUX
aiua-8788	57	28	offered	offer	VERB
aiua-8788	57	29	but	but	CCONJ
aiua-8788	57	30	the	the	DET
aiua-8788	57	31	patient	patient	NOUN
aiua-8788	57	32	died	die	VERB
aiua-8788	57	33	6	6	NUM
aiua-8788	57	34	months	month	NOUN
aiua-8788	57	35	later	later	ADV
aiua-8788	57	36	.	.	PUNCT
aiua-8788	58	1	conclusions	conclusion	NOUN
aiua-8788	58	2	neuroendocrine	neuroendocrine	NOUN
aiua-8788	58	3	tumours	tumour	NOUN
aiua-8788	58	4	are	be	AUX
aiua-8788	58	5	uncommon	uncommon	ADJ
aiua-8788	58	6	entities1	entities1	NOUN
aiua-8788	58	7	which	which	DET
aiua-8788	58	8	origin	origin	NOUN
aiua-8788	58	9	from	from	ADP
aiua-8788	58	10	cells	cell	NOUN
aiua-8788	58	11	of	of	ADP
aiua-8788	58	12	neuro	neuro	NOUN
aiua-8788	58	13	-	-	PUNCT
aiua-8788	58	14	endocrine	endocrine	NOUN
aiua-8788	58	15	system	system	NOUN
aiua-8788	58	16	and	and	CCONJ
aiua-8788	58	17	may	may	AUX
aiua-8788	58	18	potentially	potentially	ADV
aiua-8788	58	19	involve	involve	VERB
aiua-8788	58	20	all	all	DET
aiua-8788	58	21	human	human	ADJ
aiua-8788	58	22	tissues	tissue	NOUN
aiua-8788	58	23	.	.	PUNCT
aiua-8788	59	1	gastrointestinal	gastrointestinal	ADJ
aiua-8788	59	2	localization	localization	NOUN
aiua-8788	59	3	is	be	AUX
aiua-8788	59	4	quite	quite	ADV
aiua-8788	59	5	common	common	ADJ
aiua-8788	59	6	while	while	SCONJ
aiua-8788	59	7	genitourinary	genitourinary	ADJ
aiua-8788	59	8	is	be	AUX
aiua-8788	59	9	rare	rare	ADJ
aiua-8788	59	10	.	.	PUNCT
aiua-8788	60	1	neuroendocrine	neuroendocrine	ADJ
aiua-8788	60	2	small	small	ADJ
aiua-8788	60	3	-	-	PUNCT
aiua-8788	60	4	cell	cell	NOUN
aiua-8788	60	5	carcinoma	carcinoma	NOUN
aiua-8788	60	6	of	of	ADP
aiua-8788	60	7	the	the	DET
aiua-8788	60	8	bladder	bladder	NOUN
aiua-8788	60	9	is	be	AUX
aiua-8788	60	10	a	a	DET
aiua-8788	60	11	non	non	ADJ
aiua-8788	60	12	-	-	ADJ
aiua-8788	60	13	urothelial	urothelial	ADJ
aiua-8788	60	14	histotype	histotype	NOUN
aiua-8788	60	15	:	:	PUNCT
aiua-8788	60	16	it	it	PRON
aiua-8788	60	17	is	be	AUX
aiua-8788	60	18	highly	highly	ADV
aiua-8788	60	19	aggressive	aggressive	ADJ
aiua-8788	60	20	and	and	CCONJ
aiua-8788	60	21	diagnosed	diagnose	VERB
aiua-8788	60	22	mainly	mainly	ADV
aiua-8788	60	23	at	at	ADP
aiua-8788	60	24	advanced	advanced	ADJ
aiua-8788	60	25	stages	stage	NOUN
aiua-8788	60	26	.	.	PUNCT
aiua-8788	61	1	it	it	PRON
aiua-8788	61	2	’s	’s	AUX
aiua-8788	61	3	considered	consider	VERB
aiua-8788	61	4	as	as	ADP
aiua-8788	61	5	an	an	DET
aiua-8788	61	6	aggressive	aggressive	ADJ
aiua-8788	61	7	tumor	tumor	NOUN
aiua-8788	61	8	being	be	AUX
aiua-8788	61	9	characterized	characterize	VERB
aiua-8788	61	10	by	by	ADP
aiua-8788	61	11	poor	poor	ADJ
aiua-8788	61	12	prognosis	prognosis	NOUN
aiua-8788	61	13	and	and	CCONJ
aiua-8788	61	14	limited	limited	ADJ
aiua-8788	61	15	life	life	NOUN
aiua-8788	61	16	expectancy	expectancy	NOUN
aiua-8788	61	17	.	.	PUNCT
aiua-8788	62	1	small	small	ADJ
aiua-8788	62	2	-	-	PUNCT
aiua-8788	62	3	cell	cell	NOUN
aiua-8788	62	4	carcinoma	carcinoma	NOUN
aiua-8788	62	5	is	be	AUX
aiua-8788	62	6	a	a	DET
aiua-8788	62	7	type	type	NOUN
aiua-8788	62	8	of	of	ADP
aiua-8788	62	9	bladder	bladder	NOUN
aiua-8788	62	10	net	net	NOUN
aiua-8788	62	11	along	along	ADP
aiua-8788	62	12	with	with	ADP
aiua-8788	62	13	large	large	ADJ
aiua-8788	62	14	-	-	PUNCT
aiua-8788	62	15	cell	cell	NOUN
aiua-8788	62	16	variant	variant	NOUN
aiua-8788	62	17	.	.	PUNCT
aiua-8788	63	1	to	to	ADP
aiua-8788	63	2	date	date	NOUN
aiua-8788	63	3	no	no	DET
aiua-8788	63	4	treatment	treatment	NOUN
aiua-8788	63	5	has	have	AUX
aiua-8788	63	6	shown	show	VERB
aiua-8788	63	7	established	establish	VERB
aiua-8788	63	8	efficacy	efficacy	NOUN
aiua-8788	63	9	.	.	PUNCT
aiua-8788	64	1	whenever	whenever	SCONJ
aiua-8788	64	2	considering	consider	VERB
aiua-8788	64	3	the	the	DET
aiua-8788	64	4	high	high	ADJ
aiua-8788	64	5	risk	risk	NOUN
aiua-8788	64	6	of	of	ADP
aiua-8788	64	7	metastatic	metastatic	ADJ
aiua-8788	64	8	spread	spread	NOUN
aiua-8788	64	9	and	and	CCONJ
aiua-8788	64	10	the	the	DET
aiua-8788	64	11	poor	poor	ADJ
aiua-8788	64	12	prognosis	prognosis	NOUN
aiua-8788	64	13	,	,	PUNCT
aiua-8788	64	14	a	a	DET
aiua-8788	64	15	multimodal	multimodal	ADJ
aiua-8788	64	16	approach	approach	NOUN
aiua-8788	64	17	is	be	AUX
aiua-8788	64	18	highly	highly	ADV
aiua-8788	64	19	suggested	suggest	VERB
aiua-8788	64	20	.	.	PUNCT
aiua-8788	65	1	turb	turb	PROPN
aiua-8788	65	2	alone	alone	ADV
aiua-8788	65	3	is	be	AUX
aiua-8788	65	4	uneffective	uneffective	ADJ
aiua-8788	65	5	in	in	ADP
aiua-8788	65	6	disease	disease	NOUN
aiua-8788	65	7	control	control	NOUN
aiua-8788	65	8	due	due	ADP
aiua-8788	65	9	to	to	ADP
aiua-8788	65	10	its	its	PRON
aiua-8788	65	11	aggressive	aggressive	ADJ
aiua-8788	65	12	nature	nature	NOUN
aiua-8788	65	13	.	.	PUNCT
aiua-8788	66	1	unless	unless	SCONJ
aiua-8788	66	2	metastatic	metastatic	ADJ
aiua-8788	66	3	,	,	PUNCT
aiua-8788	66	4	radical	radical	ADJ
aiua-8788	66	5	cystectomy	cystectomy	NOUN
aiua-8788	66	6	and	and	CCONJ
aiua-8788	66	7	adjuvant	adjuvant	ADJ
aiua-8788	66	8	chemotherapy	chemotherapy	NOUN
aiua-8788	66	9	represent	represent	VERB
aiua-8788	66	10	the	the	DET
aiua-8788	66	11	gold	gold	ADJ
aiua-8788	66	12	standard	standard	NOUN
aiua-8788	66	13	.	.	PUNCT
aiua-8788	67	1	immuno	immuno	PROPN
aiua-8788	67	2	ther	ther	INTJ
aiua-8788	67	3	apy	apy	PROPN
aiua-8788	67	4	has	have	AUX
aiua-8788	67	5	been	be	AUX
aiua-8788	67	6	proposed	propose	VERB
aiua-8788	67	7	but	but	CCONJ
aiua-8788	67	8	still	still	ADV
aiua-8788	67	9	under	under	ADP
aiua-8788	67	10	debate	debate	NOUN
aiua-8788	67	11	.	.	PUNCT
aiua-8788	68	1	given	give	VERB
aiua-8788	68	2	its	its	PRON
aiua-8788	68	3	rarity	rarity	NOUN
aiua-8788	68	4	and	and	CCONJ
aiua-8788	68	5	the	the	DET
aiua-8788	68	6	absence	absence	NOUN
aiua-8788	68	7	of	of	ADP
aiua-8788	68	8	randomized	randomized	ADJ
aiua-8788	68	9	trials	trial	NOUN
aiua-8788	68	10	,	,	PUNCT
aiua-8788	68	11	the	the	DET
aiua-8788	68	12	therapeutic	therapeutic	ADJ
aiua-8788	68	13	management	management	NOUN
aiua-8788	68	14	of	of	ADP
aiua-8788	68	15	this	this	DET
aiua-8788	68	16	tumor	tumor	NOUN
aiua-8788	68	17	remains	remain	VERB
aiua-8788	68	18	difficult	difficult	ADJ
aiua-8788	68	19	and	and	CCONJ
aiua-8788	68	20	finding	find	VERB
aiua-8788	68	21	useful	useful	ADJ
aiua-8788	68	22	resources	resource	NOUN
aiua-8788	68	23	for	for	ADP
aiua-8788	68	24	physicians	physician	NOUN
aiua-8788	68	25	is	be	AUX
aiua-8788	68	26	troublesome	troublesome	ADJ
aiua-8788	68	27	yet	yet	ADV
aiua-8788	68	28	.	.	PUNCT
aiua-8788	69	1	references	reference	NOUN
aiua-8788	69	2	1	1	NUM
aiua-8788	69	3	.	.	PUNCT
aiua-8788	70	1	al	al	PROPN
aiua-8788	70	2	-	-	PUNCT
aiua-8788	70	3	ahmadie	ahmadie	PROPN
aiua-8788	70	4	h	h	NOUN
aiua-8788	70	5	,	,	PUNCT
aiua-8788	70	6	iyer	iyer	PROPN
aiua-8788	70	7	g.	g.	PROPN
aiua-8788	70	8	updates	update	VERB
aiua-8788	70	9	on	on	ADP
aiua-8788	70	10	the	the	DET
aiua-8788	70	11	genetics	genetic	NOUN
aiua-8788	70	12	and	and	CCONJ
aiua-8788	70	13	molecular	molecular	ADJ
aiua-8788	70	14	subtypes	subtype	NOUN
aiua-8788	70	15	of	of	ADP
aiua-8788	70	16	urothelial	urothelial	ADJ
aiua-8788	70	17	carcinoma	carcinoma	NOUN
aiua-8788	70	18	and	and	CCONJ
aiua-8788	70	19	select	select	ADJ
aiua-8788	70	20	variants	variant	NOUN
aiua-8788	70	21	.	.	PUNCT
aiua-8788	71	1	surg	surg	NOUN
aiua-8788	71	2	pathol	pathol	VERB
aiua-8788	71	3	clin	clin	PROPN
aiua-8788	71	4	.	.	PUNCT
aiua-8788	72	1	2018	2018	NUM
aiua-8788	72	2	;	;	PUNCT
aiua-8788	72	3	11:713	11:713	NUM
aiua-8788	72	4	-	-	SYM
aiua-8788	72	5	723	723	NUM
aiua-8788	72	6	.	.	NOUN
aiua-8788	73	1	2	2	NUM
aiua-8788	73	2	.	.	X
aiua-8788	73	3	cramer	cramer	PROPN
aiua-8788	73	4	sf	sf	PROPN
aiua-8788	73	5	,	,	PUNCT
aiua-8788	73	6	aikawa	aikawa	PROPN
aiua-8788	73	7	m	m	PROPN
aiua-8788	73	8	,	,	PUNCT
aiua-8788	73	9	cebelin	cebelin	PROPN
aiua-8788	73	10	m.	m.	NOUN
aiua-8788	73	11	neurosecretory	neurosecretory	NOUN
aiua-8788	73	12	granules	granule	NOUN
aiua-8788	73	13	in	in	ADP
aiua-8788	73	14	small	small	ADJ
aiua-8788	73	15	cell	cell	NOUN
aiua-8788	73	16	invasive	invasive	ADJ
aiua-8788	73	17	carcinoma	carcinoma	NOUN
aiua-8788	73	18	of	of	ADP
aiua-8788	73	19	the	the	DET
aiua-8788	73	20	urinary	urinary	ADJ
aiua-8788	73	21	bladder	bladder	NOUN
aiua-8788	73	22	.	.	PUNCT
aiua-8788	74	1	cancer	cancer	NOUN
aiua-8788	74	2	.	.	PUNCT
aiua-8788	75	1	1981	1981	NUM
aiua-8788	75	2	;	;	PUNCT
aiua-8788	75	3	47:724	47:724	NUM
aiua-8788	75	4	-	-	SYM
aiua-8788	75	5	30	30	NUM
aiua-8788	75	6	.	.	PUNCT
aiua-8788	76	1	3	3	X
aiua-8788	76	2	.	.	X
aiua-8788	76	3	siefker	siefker	NOUN
aiua-8788	76	4	-	-	PUNCT
aiua-8788	76	5	radtke	radtke	NOUN
aiua-8788	76	6	ao	ao	PROPN
aiua-8788	76	7	,	,	PUNCT
aiua-8788	76	8	dinney	dinney	PROPN
aiua-8788	76	9	cp	cp	PROPN
aiua-8788	76	10	,	,	PUNCT
aiua-8788	76	11	abrahams	abrahams	PROPN
aiua-8788	76	12	na	na	PROPN
aiua-8788	76	13	,	,	PUNCT
aiua-8788	76	14	et	et	PROPN
aiua-8788	76	15	al	al	PROPN
aiua-8788	76	16	.	.	PROPN
aiua-8788	77	1	evidence	evidence	NOUN
aiua-8788	77	2	supporting	support	VERB
aiua-8788	77	3	preoperative	preoperative	ADJ
aiua-8788	77	4	chemotherapy	chemotherapy	NOUN
aiua-8788	77	5	for	for	ADP
aiua-8788	77	6	small	small	ADJ
aiua-8788	77	7	cell	cell	NOUN
aiua-8788	77	8	carcinoma	carcinoma	NOUN
aiua-8788	77	9	of	of	ADP
aiua-8788	77	10	the	the	DET
aiua-8788	77	11	bladder	bladder	NOUN
aiua-8788	77	12	:	:	PUNCT
aiua-8788	77	13	a	a	DET
aiua-8788	77	14	retrospective	retrospective	ADJ
aiua-8788	77	15	review	review	NOUN
aiua-8788	77	16	of	of	ADP
aiua-8788	77	17	the	the	DET
aiua-8788	77	18	m.d	m.d	PROPN
aiua-8788	77	19	.	.	PROPN
aiua-8788	77	20	anderson	anderson	PROPN
aiua-8788	77	21	cancer	cancer	PROPN
aiua-8788	77	22	experience	experience	NOUN
aiua-8788	77	23	.	.	PUNCT
aiua-8788	78	1	j	j	PROPN
aiua-8788	78	2	urol	urol	PROPN
aiua-8788	78	3	.	.	PUNCT
aiua-8788	78	4	2004	2004	NUM
aiua-8788	78	5	;	;	PUNCT
aiua-8788	79	1	172:481	172:481	NUM
aiua-8788	79	2	-	-	SYM
aiua-8788	79	3	484	484	NUM
aiua-8788	79	4	.	.	PUNCT
aiua-8788	79	5	figure	figure	NOUN
aiua-8788	79	6	1	1	NUM
aiua-8788	79	7	.	.	PUNCT
aiua-8788	79	8	abdominal	abdominal	ADJ
aiua-8788	79	9	contrast	contrast	NOUN
aiua-8788	79	10	enhanced	enhance	VERB
aiua-8788	79	11	ct	ct	NUM
aiua-8788	79	12	showing	show	VERB
aiua-8788	79	13	a	a	DET
aiua-8788	79	14	right	right	ADJ
aiua-8788	79	15	wall	wall	NOUN
aiua-8788	79	16	bladder	bladder	NOUN
aiua-8788	79	17	lesion	lesion	NOUN
aiua-8788	79	18	.	.	PUNCT
aiua-8788	80	1	figure	figure	NOUN
aiua-8788	80	2	2	2	NUM
aiua-8788	80	3	.	.	X
aiua-8788	80	4	microscopic	microscopic	ADJ
aiua-8788	80	5	finding	finding	NOUN
aiua-8788	80	6	showing	show	VERB
aiua-8788	80	7	small	small	ADJ
aiua-8788	80	8	cell	cell	NOUN
aiua-8788	80	9	neuroendocrine	neuroendocrine	NOUN
aiua-8788	80	10	bladder	bladder	NOUN
aiua-8788	80	11	cancer	cancer	NOUN
aiua-8788	80	12	reacting	react	VERB
aiua-8788	80	13	to	to	ADP
aiua-8788	80	14	synaptophysin	synaptophysin	NOUN
aiua-8788	80	15	(	(	PUNCT
aiua-8788	80	16	original	original	ADJ
aiua-8788	80	17	magnification	magnification	NOUN
aiua-8788	80	18	x	x	NOUN
aiua-8788	80	19	400	400	NUM
aiua-8788	80	20	)	)	PUNCT
aiua-8788	80	21	.	.	PUNCT
aiua-8788	81	1	figure	figure	VERB
aiua-8788	81	2	3	3	NUM
aiua-8788	81	3	-	-	SYM
aiua-8788	81	4	4	4	NUM
aiua-8788	81	5	.	.	PUNCT
aiua-8788	81	6	whole	whole	ADJ
aiua-8788	81	7	body	body	NOUN
aiua-8788	81	8	contrast	contrast	NOUN
aiua-8788	81	9	enhanced	enhance	VERB
aiua-8788	81	10	ct	ct	NUM
aiua-8788	81	11	showing	show	VERB
aiua-8788	81	12	brain	brain	NOUN
aiua-8788	81	13	and	and	CCONJ
aiua-8788	81	14	liver	liver	NOUN
aiua-8788	81	15	multiple	multiple	ADJ
aiua-8788	81	16	metastases	metastasis	NOUN
aiua-8788	81	17	in	in	ADP
aiua-8788	81	18	small	small	ADJ
aiua-8788	81	19	cell	cell	NOUN
aiua-8788	81	20	neuroendocrine	neuroendocrine	NOUN
aiua-8788	81	21	carcinoma	carcinoma	NOUN
aiua-8788	81	22	of	of	ADP
aiua-8788	81	23	the	the	DET
aiua-8788	81	24	bladder	bladder	NOUN
aiua-8788	81	25	(	(	PUNCT
aiua-8788	81	26	sccb	sccb	NOUN
aiua-8788	81	27	)	)	PUNCT
aiua-8788	81	28	.	.	PUNCT
aiua-8788	82	1	correspondence	correspondence	NOUN
aiua-8788	82	2	valerio	valerio	PROPN
aiua-8788	82	3	olivieri	olivieri	PROPN
aiua-8788	82	4	,	,	PUNCT
aiua-8788	82	5	md	md	PROPN
aiua-8788	82	6	valerio.olivieri@uniroma1.it	valerio.olivieri@uniroma1.it	NOUN
aiua-8788	82	7	luca	luca	PROPN
aiua-8788	82	8	bellei	bellei	NOUN
aiua-8788	82	9	,	,	PUNCT
aiua-8788	82	10	md	md	PROPN
aiua-8788	82	11	massimo	massimo	PROPN
aiua-8788	82	12	massarelli	massarelli	PROPN
aiua-8788	82	13	,	,	PUNCT
aiua-8788	82	14	md	md	PROPN
aiua-8788	82	15	gabriele	gabriele	PROPN
aiua-8788	82	16	ruggiero	ruggiero	PROPN
aiua-8788	82	17	,	,	PUNCT
aiua-8788	82	18	md	md	PROPN
aiua-8788	82	19	division	division	NOUN
aiua-8788	82	20	of	of	ADP
aiua-8788	82	21	urology	urology	NOUN
aiua-8788	82	22	,	,	PUNCT
aiua-8788	82	23	ivrea	ivrea	ADJ
aiua-8788	82	24	civil	civil	ADJ
aiua-8788	82	25	hospital	hospital	NOUN
aiua-8788	82	26	(	(	PUNCT
aiua-8788	82	27	asl	asl	PROPN
aiua-8788	82	28	to4	to4	NOUN
aiua-8788	82	29	)	)	PUNCT
aiua-8788	82	30	,	,	PUNCT
aiua-8788	82	31	ivrea	ivrea	PROPN
aiua-8788	82	32	(	(	PUNCT
aiua-8788	82	33	turin	turin	PROPN
aiua-8788	82	34	)	)	PUNCT
aiua-8788	82	35	(	(	PUNCT
aiua-8788	82	36	italy	italy	PROPN
aiua-8788	82	37	)	)	PUNCT
aiua-8788	83	1	daniele	daniele	PROPN
aiua-8788	83	2	griffa	griffa	PROPN
aiua-8788	83	3	,	,	PUNCT
aiua-8788	83	4	md	md	PROPN
aiua-8788	83	5	danilo	danilo	PROPN
aiua-8788	83	6	abate	abate	PROPN
aiua-8788	83	7	,	,	PUNCT
aiua-8788	83	8	md	md	PROPN
aiua-8788	83	9	nicoletta	nicoletta	PROPN
aiua-8788	83	10	serra	serra	PROPN
aiua-8788	83	11	,	,	PUNCT
aiua-8788	83	12	md	md	PROPN
aiua-8788	83	13	division	division	NOUN
aiua-8788	83	14	of	of	ADP
aiua-8788	83	15	urology	urology	NOUN
aiua-8788	83	16	,	,	PUNCT
aiua-8788	83	17	ciriè	ciriè	PROPN
aiua-8788	83	18	hospital	hospital	NOUN
aiua-8788	83	19	(	(	PUNCT
aiua-8788	83	20	aslto4	aslto4	NOUN
aiua-8788	83	21	)	)	PUNCT
aiua-8788	83	22	,	,	PUNCT
aiua-8788	83	23	ciriè	ciriè	PROPN
aiua-8788	83	24	(	(	PUNCT
aiua-8788	83	25	turin	turin	PROPN
aiua-8788	83	26	)	)	PUNCT
aiua-8788	83	27	(	(	PUNCT
aiua-8788	83	28	italy	italy	PROPN
aiua-8788	83	29	)	)	PUNCT
aiua-8788	83	30	valentina	valentina	PROPN
aiua-8788	83	31	fortunati	fortunati	PROPN
aiua-8788	83	32	,	,	PUNCT
aiua-8788	83	33	md	md	PROPN
aiua-8788	83	34	valerio.olivieri@uniroma1.it	valerio.olivieri@uniroma1.it	PROPN
aiua-8788	83	35	division	division	NOUN
aiua-8788	83	36	of	of	ADP
aiua-8788	83	37	pathology	pathology	NOUN
aiua-8788	83	38	,	,	PUNCT
aiua-8788	83	39	hospital	hospital	NOUN
aiua-8788	83	40	“	"	PUNCT
aiua-8788	83	41	policlinico	policlinico	NOUN
aiua-8788	83	42	of	of	ADP
aiua-8788	83	43	tor	tor	PROPN
aiua-8788	83	44	vergata	vergata	NOUN
aiua-8788	83	45	”	"	PUNCT
aiua-8788	83	46	,	,	PUNCT
aiua-8788	83	47	rome	rome	PROPN
aiua-8788	83	48	(	(	PUNCT
aiua-8788	83	49	italy	italy	PROPN
aiua-8788	83	50	)	)	PUNCT
aiua-8788	83	51	emanuele	emanuele	PROPN
aiua-8788	83	52	corongiu	corongiu	PROPN
aiua-8788	83	53	,	,	PUNCT
aiua-8788	83	54	md	md	PROPN
aiua-8788	83	55	(	(	PUNCT
aiua-8788	83	56	corresponding	correspond	VERB
aiua-8788	83	57	author	author	NOUN
aiua-8788	83	58	)	)	PUNCT
aiua-8788	83	59	emanuele.corongiu@libero.it	emanuele.corongiu@libero.it	PROPN
aiua-8788	83	60	flavio	flavio	PROPN
aiua-8788	83	61	forte	forte	PROPN
aiua-8788	83	62	,	,	PUNCT
aiua-8788	83	63	md	md	PROPN
aiua-8788	83	64	flavioforte@hotmail.com	flavioforte@hotmail.com	PROPN
aiua-8788	83	65	division	division	NOUN
aiua-8788	83	66	of	of	ADP
aiua-8788	83	67	urology	urology	NOUN
aiua-8788	83	68	,	,	PUNCT
aiua-8788	83	69	hospital	hospital	NOUN
aiua-8788	83	70	“	"	PUNCT
aiua-8788	83	71	madre	madre	PROPN
aiua-8788	83	72	giuseppina	giuseppina	PROPN
aiua-8788	83	73	vannini	vannini	PROPN
aiua-8788	83	74	”	"	PUNCT
aiua-8788	83	75	,	,	PUNCT
aiua-8788	83	76	rome	rome	PROPN
aiua-8788	83	77	(	(	PUNCT
aiua-8788	83	78	italy	italy	PROPN
aiua-8788	83	79	)	)	PUNCT
aiua-8788	84	1	14corongiu1_stesura	14corongiu1_stesura	NUM
aiua-8788	84	2	seveso	seveso	NOUN
aiua-8788	84	3	25/09/20	25/09/20	PROPN
aiua-8788	84	4	13:12	13:12	NUM
aiua-8788	84	5	pagina	pagina	NOUN
aiua-8788	84	6	212	212	NUM