artofmedicineimsj: A Pathfinder

This is a computer-generated pathfinder created against the Distant Reader study called artofmedicineimsj.

Each Distant Reader study carrel is composed of many individual items. Each item is bibliographically described with author, title, date, summary, and keyword values. Below is a list of the items' most signficant keywords as well as lists of the items themselves. Purpusing the content of this pathfinder provides the student, researcher, or scholar with one way to get their heads around the scope of the carrel. The keywords include:

Medicine; Group; Disease; Children; Treatment; Production; Diabetes; Ibs; Acd; Implants; Depression; Average; Criteria; Century; Akhir; Foci; Approach

Depending on how this pathfinder was created, many of the bibliographic sections will include elaborations on the meaning(s) of the given keywords. These elaborations were generated by feeding the items' summaries to a large langauge model and asking the model to address the question, "What is X?", where "X" is the keyword. The result will be a few sentences of elaboration. Be forewarned. The elaborations are often plausible, but they should not be take as truth. Instead, they should be taken as points for consideration.

• OPHTHALMOLOGIC COMPLICATIONS IN THE STRUCTURE OF THE CLINICAL FEATURES OF NOVEL CORONAVIRUS INFECTION (COVID-19) by Kasimova , M. S.; Iminova , M. M.; Ashurov , O. M. (2021) - As of today, the sources do not portray the variations of ophthalmic complications and specific management tactics for patients with severe forms of damage to the organ of vision under COVID-19. Internet address: http://artofmedicineimsj.us E-mail: info@artofmedicineimsj.us 11931 Barlow Pl Philadelphia, PA 19116, USA +1 (929) 266-0862 Art of Medicine International Medical Scientific journal CHIEF EDITOR Dr. Pascual Izquierdo-Egea EDITORIAL BOARD Prof. Dr. Francesco Albano Dr. Catherine J. Andersen Prof. Dr. Sandro Ardizzone Dr. Dmitriy Atochin Prof. Dr. Antonio Aversa Prof. Dr. Tamam Bakchoul Prof. Dr. Pierre-Gregoire Guinot Prof. Dr. Rainer Haak Prof. Henner Hanssen Art of Medicine International Medical Scientific Journal Volume-1 Issue-1 4 CONTENT Tursunova L. D., Jabbarov O. O. APPLICATION OF SAKABUTRIL/VALSARTAN IN PATIENTS WITH CHRONIC KIDNEY DISEASE WITH TYPE 2 DIABETES MELLITUS...............................5 L.S. Khamraeva., D.U. Narzullaeva FEATURES OF CALCULATING THE OPTICAL POWER OF AN INTRAOCULAR LENS IN CHILDREN WITH CONGENITAL CATARACTS Keywords: art; complications; covid-19; medicine; organ; patients
• IMPROVEMENT OF METHODS FOR CORRECTION OF CLINICAL AND IMMUNOLOGICAL DISORDERS IN COMORBID STATE OF CHRONIC GAYMORITIS AFTER COVID-19 by Fattayeva , D.R.; Rizayev, J.A.; Rakhimova , D.A. (2021) - Stress and negative emotions lead to an increase in blood levels of cortisol, a hormone that is a poison for immune cells [12,15]. - Some medications (antibiotics, cortisone and pain relieversa) reduce the mobility of immune cells, their aggressiveness towards pathogens, and the ability to produce antibodies [6]. Keywords: antibodies; art; body; cells; drugs; effect; immunity; journal; medical; medicine; patients; preparations; sinusitis; system
• FEATURES OF IMMUNOBIOLOGICAL HETEROGENEITY IN PATIENTS WITH OSTEOSARCOMA by Polatova , D.Sh.; Abdukarimov , Kh.G.; Davletov , R.R.; Savkin, A.V.; Sultanov , B.B. (2021) - 8.Curotto de Lafaille M., Lino A., Kutchukhidze N. CD25- T cells generate CD25+ Foxo3+ regulatory T-cells by peripheral expansion // J. Immunol. - 2004. 12.Gilliet M., Liu Y. Generation of human CD8 T regulatory cells by CD40 ligandactivated plasmacytoid dendritic cells // J. Exp Med. – 2002. – V.195. - P.695-704. Keywords: art; cells; disease; immunity; lymphocytes; medicine; osteosarcoma; patients
• CORONAVIRUS INFECTION AND CARDIOVASCULAR DISEASES by Abdukodirova N.M.; Tulaboeva G.M.; Saidov Kh.Kh.; Fazilbekova Z.N. (2021) - Mortality rates of COVID-19 patients by selected comorbidities. Myocardial injury in including acute COVID-19 patients may present with ST elevations in the absence of obstructive coronary artery disease (CAD). Keywords: ace; covid-19; disease; drugs; inhibitors; medicine; patients
• PREPARATIONS ON LONGITUDINAL DEFORMATION OF THE LEFT VENTRICLE by Mamurov O.I.; Gafur-Akhunov M.A.; Dadamyants N.G. (2021) - Perhaps the maximum contribution to the development of cardiovascular pathology in cancer patients is made by the toxic effects of anticancer therapy. Uzbekistan Abstract To compare the indicators of longitudinal deformation of the left ventricular myocardium and the rate of deformation of the LV myocardium in women before and after receiving anthracyclines chemotherapy in breast cancer(BC) patients Keywords: myocardium, left ventricle, oncological, cardiovascular, treatment. Keywords: journal; medicine; patients
• CORRELATION RELATIONSHIP OF IMMUNE-METABOLIC PARAMETERS IN ARTERIAL HYPERTENSION by Navruzova Shakar Istamovna; Shadmanova Nargis Kurbanovna; Soliev Alisher Urakovich (2021) - It was found that an increase in the level of IgG in the blood confirms the risk of developing atherosclerosis in hypertension of the 1st degree, and a decrease in the level of IgG in the blood shows the development of secondary immunodeficiency. Each result obtained determines the further tactics of management of patients with hypertension of the 1st degree. Keywords: blood; hypertension; journal; medical; medicine; relationship
• THE VALUE OF PERIMETRIC AND ELECTROPHYSIOLOGICAL DIAGNOSTIC CRITERIA IN EARLY PRIMARY OPEN-ANGLE GLAUCOMA by Yusupov Azamat Farkhadovich; Karimova Muyassar Khamitovna; Zakirkhodjaeva Mastona Azizkhodzhayevna; Abdushukurova Asal Azamat kizi (2021) - Art of Medicine Volume-1 International Medical Scientific Journal Issue-2 10.5281/zenodo.5517016 101 Comparative analysis of perimetric parameters in patients with suspected glaucoma Control group Clinical group Perimetric indices SAP SWAP SAP SWAP MD, db 0,75 ± 0,25* 0,93 ± 0,5 –1,57 ± 0,45 * –1,75 ± 0,75 MS, db 21 ± 1,5 25 ± 2,75 18 ± 2,5 22 ± 3,5 PSD, db 2,37 ± 0,75 3,25 ± 1,5* 3,37 ± 1,5 5,75 ± 2,5* 10,73 ± 1,85* 14,4 ± 1,85 17,2 ± 2,5* D-wave amplitude, mV blue-conical ERG - 34 ± 0,75* - 28 ± 1,25* Keywords: diagnosis; erg; glaucoma; medicine; patients; perimetry; stimulus
• FEATURES OF TRAUMATIC INJURIES OF THE ORAL MUCOSA: LITERATURE REVIEW by Kamalova Mekhriniso Кilichevna; Sharipova Gulnihol Idievna (2021) - Mechanical injuries oral cavity of early childhood children and preschool age // «Cutting Edge-Science» International scientific and practical conference. Abstract Among the various pathological conditions of oral mucosa in children, traumatic injuries are quite widespread, which can be the result of mechanical, thermal, chemical, electrical and radiation exposure. Keywords: art; cavity; children; day; days; journal; medical; medicine; mucosa; oil; radiation; solution; treatment; ulcer
• EFFICACY OF EMPAGLIFLOZIN IN OLDER PATIENTS WITH CHRONIC HEART FAILURE WITH PRESERVED LEFT VENTRICULAR EJECTION FRACTION by Tulaboeva G.M.; Talipova Yu.Sh.; Sagatova X.M.; Xusanov A.A.; Abdukodirova N.M. (2021) - Patients, depending on the therapy performed by the method of random sampling, were divided into 2 groups: group 1 (n = 75, main group) of patients on the background of standard CHF therapy took empagliflozin (Emgalif, Orville services) 10 mg / day and group 2 (control group, n = 40) who took only standard therapy. Internet address: http://artofmedicineimsj.us E-mail: info@artofmedicineimsj.us 11931 Barlow Pl Philadelphia, PA 19116, USA +1 (929) 266-0862 Art of Medicine Volume-1 International Medical Scientific Journal Issue-2 10.5281/zenodo.5520856 118 Efficacy of empagliflozin in older patients with chronic heart failure with preserved left ventricular ejection fraction Tulaboeva G.M., Talipova Yu. Keywords: chf; empagliflozin; group; heart; journal; medicine; patients; study
• STUDY OF THE APPLICATION OF MAGNETOTHERAPY IN COMPLEX WITH GANODERMA LUCIDUM EXTRACT ON THE STATE OF THE IMMUNOCOMPETENT SYSTEM IN THE TREATMENT OF PATIENTS WITH DUAL ULTRA DISEASE WITH DYSBIOSIS. by Kadirova S.R.; Khamrabaeva F.I. (2021) - 43.3% of patients in 1st, 16.7% - 2nd and 56.6 ° finished without treatment effect. Patients of the second group (30 patients) underwent complex treatment: MT according to the above method, as well as a synbiotic consisting of an extract of Ganoderma Lucidum - 1 capsule 2 times a day with meals for 21 days In the third comparison group (30 patients), the effect of MT from the “Olymp-1” apparatus (placebo) was imitated. Keywords: complex; effect; group; medicine; patients; treatment
• HYGIENIC ASSESSMENT OF LEADING HARMFUL FACTORS IN PHARMACEUTICAL ENTERPRISES by Iskandarova G.T.; Tashpulatova M.N.; Samigova N.R.; Kurbanova Sh.I.; Sherkuzieva G.F.; Yusupkhujaeva A.M. (2021) - Keywords: pharmaceutical companies, injectable medications, technological process, harmful factors, noise, chemical factor, permissible norms, preventive measures. Sanitary rules and norms RUz No. 0325-16 Sanitary norms of permissible noise levels at workplaces. Keywords: factors; medical; medicine; noise; pharmaceutical; production
• RESULTS OF ASSESSMENT OF CLASS AND DEGREE OF HARMFULNESS OF WORKING CONDITIONS OF MEDICAL WORKERS, INDEXED BY COMPLEXITY AND SEVERITY OF THE WORK PROCESS by Sabirova G.A.; Sadikov A.U.; Khamrakulova M.A.; Sadikov U.A. (2021) - Ivanov A. V., Tafeeva E.A. Effectiveness of sanitary and hygienic measures in areas of oil production // Hygiene and sanitation. - 2004. - №1.-С. 22-25. 11. Labor hygiene of oil workers working on the mainland and continental shelf: Keywords: conditions; factors; gas; industry; medical; medicine; oil; production; workers; working
• OBESITY AND UTERINE FIBROIDS by I.M. Tojieva; Z.Yu. Khalimova; Sh.A. Zufarova (2021) - Uterine fibroids are characterized by an impaired antioxidant cellular system: potential role of hypoxia in the pathophysiology of uterine fibroids. Uterine fibroids risk and history of selected medical conditions linked with female hormones. Keywords: fibroids; medicine; obesity; risk; uterine
• THE ROLE OF ENDOTHELIAL DYSFUNCTION IN THE DEVELOPMENT OF IMMUNE MICROTHROMBOVASCULITIS by Islamova Z.S.; Inoyatova F.Kh.; Babadjanova Sh.A.; Yusupkhodjaeva Kh.S.; Kurbonova Z.Ch. (2021) - Abstract: comparative assessment of endothelial dysfunction indicators in patients with IMTV depending on the form of the disease and the characteristics of its course. The study of the vascular- platelet link of hemostasis in patients with IMTT showed a tendency to develop moderate thrombocytosis and an increase in their thrombogenic activity. Keywords: articular; disease; endothelial; form; group; imtv; journal; medical; medicine; patients; skin
• CLINICAL AND IMMUNOLOGICAL INDICATORS OF INFLAMMATORY DISEASES OF THE NERVOUS SYSTEM by M.Sh. Khozhimatova; N.A. Nasirdinova (2021) - Pa resis and paralysis Ex trapyra mine disorder s Co ordinati ng violation s Pe lvic dysfunct ion 1 Myelitis 33(97%) - 34(100% ) - 33(97,1 %) 29(85,3 %) 2 Encephalitis - 23(39,7 %) 43(74,1 %) 8(13,7%) 4(6,89%) - 3 Encephalom yelitis 25(78,1 %) 10(31,2 %) Table No. 2 The course of the inflammatory process depending on the disease № Nosology The severity of the flow Art of Medicine Volume-1 International Medical Scientific Journal Issue-3 10.5281/zenodo.5639620 42 Lung Average heavy Heavy Extremely heavy 1 Myelitis 4 (11,8%) 22 (64,7%) 8 (23,5%) - 2 Encephalitis 3 (5,2%) 16 (27,6%) 29 (50%) 10 (17,2%) 3 Encephalomyelitis - 12 (37,5%) 12 (37,5%) 8 (25%) Keywords: diseases; encephalitis; encephalomyelitis; group; journal; medical; medicine; patients
• DIFFICULTIES AND PROSPECTS FOR NON-DRUG TREATMENT OF METABOLIC SYNDROME by Badritdinova Matluba Nazhmidinovna; Nurulloeva Shakhodat Nurullo kizi (2021) - Art of Medicine Volume-1 International Medical Scientific Journal Issue-3 10.5281/zenodo.5658996 54 Diet therapy is the cornerstone of the management of MS patients, and perhaps the most difficult to manage. The main goal of MS treatment is to reduce the risk of developing CVD and type 2 diabetes. Keywords: diabetes; journal; medicine; metabolic; obesity; patients; risk; syndrome; treatment; weight
• EPILEPTIC ENCEPHALOPATHY AND ANGELMAN SYNDROME by Gulyamova Durdona Nasriddinovna (2021) - Internet address: http://artofmedicineimsj.us E-mail: info@artofmedicineimsj.us 11931 Barlow Pl Philadelphia, PA 19116, USA +1 (929) 266-0862 Art of Medicine Volume-1 International Medical Scientific Journal Issue-3 10.5281/zenodo.5717607 89 Epileptic encephalopathy and Angelman syndrome Gulyamova Durdona Nasriddinovna Dotsent at department Pediatric Neurology Center for the development of professional qualifications of medical personnel Abstract: Angelman syndrome (AS) - is a chromosomal syndrome characterized by atypical autism with intellectual retardation, epilepsy, a gross impairment of speech, motor disorders, ataxia, as well as special the behavior (happy demeanor) of patients in combination with frequent laughter or smiling bursts. Keywords: angelman; art; children; disease; journal; medicine; patients; seizures; syndrome

• DYNAMICS OF MARKERS OF BONE METABOLISM IN THE ORAL FLUID IN PATIENTS WITH DISEASES OF THE CARDIOVASCULAR SYSTEM IN PREPARATION FOR DENTAL IMPLANTATION by A.A. Khadjimetov; A.A. Yuldashev (2021) - In group II patients, bleeding of the gums was observed only in 68.7%. Changes in the parameters of osteocalcin, bone isoenzyme alkaline phosphatase and cathepsin K in the blood serum of dental patients with concomitant pathology. Keywords: bone; dental; fluid; group; journal; medical; patients
• GENEALOGICAL CHARACTERISTICS OF PATIENTS WITH CKD AT THE LEVEL OF PRIMARY HEALTH CARE by Daminova K.M.; Sabirov M.A. (2021) - Comparative analysis of the generalized family portrait of CKD patients with a generalized family portrait of a population of practically healthy people revealed a more frequent lesion of renal pathology in relatives with CKD (11.07 %). The incidence of CKD in the pedigrees of CKD patients. Keywords: ckd; disease; group; medical; patients
• COMPARATIVE ANALYSIS OF SEPARATE RESULTS OF ARTHROPLASTY FOR ASEPTIC NECROSIS OF THE FEMORAL HEAD by Akramov Vohid Rustamovich (2021) - L. Zheng, W. Wang, J. Ni Plasma interleukin level in patients with osteonecrosis of femoral head: an alarmin for osteonecrosis of the femoral head // J. Investig. Vascularized fibular grafts in patients with avascular necrosis of femoral head: A systematic review and meta-analysis/ T. Fang, E.W. Zhang, F.C. Sailes// Arch Orthop Trauma Surg. – 2013. – Vol. 133(1). Keywords: control; control group; group; months; patients; points; treatment
• METHODS AND PRINCIPLES OF EXCISION OF PERFORATED DUODENAL ULCERS by Botirov A.K.; Izatullaev I.R.; Nosirov M.M.; Botirov J.A. (2021) - Onopriev V.I., Karipidi G.K., Voskanyan S.E., Balyan A.S. Surgical pathomorphology (histotopography) of sutured duodenal ulcers. The authors have developed and implemented techniques and techniques for excision of perforated duodenal ulcers (PDU) with pylorus-preserving pyloroduodenoplasty (PDP) by preserving the integrity of the multifaceted function of the pyloric pulp (patents No. 2262 and No. 0128 IPA RUz were obtained). Keywords: excision; group; medical; pdu; pyloric; ulcer; wall
• PERIODONTAL STATE AND OPTIMIZATION OF PROSTHODONTIC DENTAL CARE IN HIV-INFECTED PATIENTS by Anvar Alimov; Sunatullo Gaffarov; Alisher Alimov (2021) - Due to the significant number of teeth destroyed as a result of the carious process and extracted teeth in HIV patients; there was an increase in the proportion of people with secondary edentulousness and needing prosthetics. Keywords: HIV infection, periodontal condition, gnatodynamometry, orthopedic dental therapy. Keywords: dental; group; hiv; journal; patients
• PROSTHETIC HIATOPLASTY IN SURGICAL TREATMENT OF HIATAL HERNIAS by Khashimov Sh.Kh.; Sadikov N.S.; Ligai R.E.; Tsoi A.O.; Tashkenbaev F.R.; Zaripov A.A. (2021) - Comparison group Main group Total Without complications 43(70,5%) 42(95,4%) 85(81%) Total: 61(100%) 44(100%) 105(100%) Keywords: comparison; complications; diaphragm; group; hiatal; journal; patients
• COMPLEX PREGRAVID PREPARATION IN THE PREVENTION OF MISCARRIAGE IN WOMEN WITH HYPERANDROGENISM by Sidikova Nigora Marifovna (2021) - The proposed and tested by us complex corrective pregravid training of patients with HA and PCOS with normal body weight, as well as with preobesity and obesity of the 1st degree, showed greater efficiency, manifested in a greater proportion of pregnant patients relative to standard pregravid training. The main groups of patients were divided by us according to the type of pregravid corrective therapy, each into 2 subgroups A and B. Pregravid preparation of patients A of subgroups I and II of groups consisted of standard conservative treatment, including biguanides (metformin 500 mg), stimulation of ovulation with agonists and antagonists of gonadotropin-releasing hormones, anti-estrogen drugs (clomiphene citrate) at 50-100 mg / day. Keywords: group; medical; patients; pregravid; saliva; women
• COMPARATIVE CHARACTERISTICS OF HEALING OF AFTHOUS STOMATITIS IN EXPERIMENT by Akbarov A.N.; Ziyadullaeva N.S.; Irismetova B.D. (2021) - Analysis of histological changes during the formation and healing of experimental aphthous ulcers in rats showed that 12 hours after the start of the Art of Medicine Volume-1 International Medical Scientific Journal Issue-3 10.5281/zenodo.5762446 109 experiment, it was determined that the stratified squamous epithelium was thinned, the mucous membrane was degraded, the lamina propria was edematous with elements of necrosis, the muscle layer was edematous with degradation, the glands were numerous (fig. 5). On the 5th day, treatment was started, the HEPROCEL powder was applied to the area of aphthous ulcer of the mucous membrane of the lower lip to form a gel on the surface of the ulcer (Fig. 1). Keywords: animals; day; fig; group; mucosa; surface; ulcer
• COMPARATIVE ANALYSIS OF THE RESULTS OF THERAPY ACCORDING TO THE PROTOCOLS ALL-BFM-95M AND ALL-MB-2008 IN UZBEKISTAN by Ibragimova S.Z. (2022) - % n % Keywords: group; patients; protocol; results; risk; treatment
• APPLICATION OF SAKABUTRIL/VALSARTAN IN PATIENTS WITH CHRONIC KIDNEY DISEASE WITH TYPE 2 DIABETES MELLITUS by Tursunova, L.D.; Jabbarov , O.O. (2021) - The article presents data on disturbances of the excretory and filtration functions of the kidneys, as well as lipid metabolism in patients with chronic kidney disease. The fundamental difference between the concept of chronic kidney disease and chronic renal failure is the inclusion in this category of patients, including those with a normal functional state of the kidneys. Keywords: chronic; ckd; diabetes; disease; group; kidney; patients; valsartan
• FEATURES OF CALCULATING THE OPTICAL POWER OF AN INTRAOCULAR LENS IN CHILDREN WITH CONGENITAL CATARACTS AT THE RISK OF DEVELOPING PSEUDOMYOPIC MYOPIA. by Khamraeva, L.S. ; Narzullaeva , D.U. (2021) - Table 1 Dynamics of children refraction (n - the number of eyes) Refraction Groups Emmetropia, disproportionate to age Hypermetropia age-appropriate (target refraction) Table 2 Dynamics of children refraction (n - the number of eyes) Refraction Groups Emmetropia, disproportionate to age Hypermetropia age-appropriate (target refraction) Keywords: children; control; group; iol; medical; refraction

• EXPERT ASSESSMENT OF SURVIVAL PROGNOSIS AND OPTIMIZATION OF APPROACHES TO EARLY EXAMINATION OF PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE by Liverko I.V.; Tashmetova G.T. (2021) - Table 3 Frequency of scoring criteria in patients with COPD with and without disabilities Indicator by indicators Score in points COPD patients with an established invalidity, n = 82 without established disability, n = 258 B M I, k g / m 2 More than 21 0 29(35,4±5,3) 1. Frequency of occurrence of functional classes of the disease in COPD In the cohort of COPD patients with disabilities, there was a trend towards an increase in the functional class of COPD disease from 11.0% to 52.4%. Keywords: copd; disability; disease; patients; points
• CARBON METAL DISORDERS IN CUSHING SYNDROME by Kholmatova. Yu.A.; Narimova G.D. (2021) - Cushing's syndrome develops over time in patients who receive glucocorticoids for inflammatory or autoimmune diseases (including bronchial asthma, rheumatoid arthritis, systemic lupus erythematosus, skin diseases). Cardiovascular risk factors and common carotid artery caliber and stiffness in patients with Cushing’s disease during active disease and 1 year after disease remission. Keywords: acth; cushing; diabetes; disease; hypercortisolism; medical; metabolism; patients; syndrome
• VIEW OF THE QUALITY OF THE LIFE IN ANKYLOSING SPONDILOARTHRITIS by Pulatova Shakhnoza Bakhtiyarovna (2022) - All these factors give them the character of social diseases, which reduce the biological, physiological and psychological activity of members of society. AS is among the most expensive in the treatment of diseases. Keywords: disease; international; life; medical; quality

• DIAGNOSTIC ROLE OF IMMUNOLOGICAL AND BIOCHEMICAL PARAMETERS IN THE GASTROINTESTINAL FOOD ALLERGY IN CHILDREN by Ganieva Shakhzoda Shavkatovna; Juraeva Firuza Rakhmatovna; 3Hamdamova Gulhayo Rakhmatovna (2021) - Consequently, in saliva, an increase in IgE is accompanied by an increase in IL-8 and a decrease in sIgA. Studies on Helicobacter pylori infection in GIA showed a weak negative association of saliva IL-8 with blood Helicobacter pylori (r=-0.29). In contrast to the correlations in Helicobacter pylori unassociated GIA, the association of GIA with Helicobacter pylori infection shows an average positive association of TNF-α saliva with IL-8 saliva (P=0.44) and a weak positive association of TNF-α saliva with IgA in the blood (P=0.20). Keywords: blood; children; gia; helicobacter; infection; medical; pylori; saliva
• STATISTICAL ANALYSIS OF THE STRUCTURE OF THE BIRTH RATE OF UNDERWEIGHT CHILDREN IN THE BUKHARA REGION by Yuldasheva Gulnoz Giyasovna; Bakhranova Nasiba Ramazanovna; Baratov Sunnat Samiyevich (2021) - Relevance The situation of premature birth and the birth of a small child is the most acute crisis situation in a woman's life and requires timely psychological assistance to a woman in labor in the dyad mother-small child One of the most urgent problems of obstetrics and neonatology is the miscarriage of pregnancy and the birth of children with a low body weight (less than 2500 g) as a result of premature birth or intrauterine fetal development delay. Keywords: birth; children; medical; weight
• ERADICATION OF HISTOPATHOLOGICAL AND BIOCHEMICAL CHANGES IN TESTES AND REPRODUCTIVE ORGANS ON EXPOSURE TO ORGANOPHOSPHATE, ETHION by Inge , K. (2021) - The discovery method creates the situation of research problems, causes similar tasks and problems of scientific research in students' consciousness, and urges them to explore and master scientific conclusions. First of all, we must make clear what is creative problem. Keywords: answer; children; problem; questions; students; teacher; teaching; theory
• CLINICAL AND INSTRUMENTAL PECULIARITIES OF THE POSTOPERATIVE PERIOD IN CHILDREN WITH TETRALOGY OF FALLOT by Akhmedova , N.R.; Matkarimova , A.A.; Kazakbaeva , T.T.; Seitbaeva , A.M. (2021) - Frequent symptoms of malformation in older children were thickening and changes in the shape of watch glasses nails and drumstick nail phalanges (85%), chest deformity in 25% of children (heart hump). Internet address: http://artofmedicineimsj.us E-mail: info@artofmedicineimsj.us 11931 Barlow Pl Philadelphia, PA 19116, USA CHIEF EDITOR Dr. Pascual Izquierdo-Egea EDITORIAL BOARD Prof. Dr. Francesco Albano Dr. Catherine J. Andersen Prof. Dr. Sandro Ardizzone Dr. Dmitriy Atochin Prof. Dr. Antonio Aversa Prof. Dr. Tamam Bakchoul Prof. Dr. Pierre-Gregoire Guinot Prof. Dr. Rainer Haak Prof. Henner Hanssen 17 Volume 1, ¹4 CLINICAL AND INSTRUMENTAL PECULIARITIES OF THE POSTOPERATIVE PERIOD IN CHILDREN WITH TETRALOGY OF FALLOT Akhmedova N.R., Matkarimova A.A., Kazakbaeva T.T., Seitbaeva A.M. Republican children's multidisciplinary medical center, Nukus city Tashkent Pediatric Medical Institute Karakalpak Medical Institute Abstract. Keywords: children; heart; medical; patients; period

• ANALYSIS OF REPARATIVE AFTER SURGICAL TREATMENT OF DIAPHYSEAL FRACTURES OF THE SHIN BONES by Gafforov A.U.; Asilova S.U.; Teshaev A.A. (2021) - Art of Medicine Volume-1 International Medical Scientific Journal Issue-3 10.5281/zenodo.5633974 9 References 1. Mamaev, V. I. Transosseous osteosynthesis and the possibility of predicting the outcomes of treatment of the consequences of bone fractures [Text] / V. I. Mamaev // Bulletin of traumatology and orthopedics them. Korzh, N. A. Prevalence of bone fractures and the results of their treatment in Ukraine (clinical and epidemiological study) Keywords: callus; diaphyseal; fractures; months; patients; treatment
• ANTHROPOMETRIC, METABOLIC AND BONE CHANGES IN WOMEN WITH PREMATURE OVARIAN FAILURE WHEN USING ESTRADIOL ANALOGUES by Khaidarova Feruza Alimovna; Fakhrutdinova Sevara Srajitdinovna; Azizov Bakhodir Sadikovich (2021) - Although our results should be validated in a larger sample, both transdermal and oral estradiol appeared to be associated with large short-term improvements in bone BMD compared with ethinyl estradiol or no therapy. To compare changes in bone, metabolic and anthropometric parameters in young women with hypergonadotropic amenorrhea (premature ovarian failure [POF], complete androgen insensitivity syndrome Keywords: bmd; bone; estradiol; patients; pof; study; treatment; women

• THE FUNCTIONAL STATE OF THE WOMEN’S BODY WORKING IN THE DRAINAGE INDUSTRY by Iskandarov Aziz Bakhromovich (2021) - The peculiarity of the technological process of mulberry production, increasing from year to year volumes of mulberry production, cause the employment of a large contingent of working women in this agricultural sector of the national economy of the republic. While in worm-houses, working women are exposed to a warming, humid, convectional microclimate. Keywords: butterflies; cocoons; conditions; production; silkworm; women; working
• CHARACTERISTICS OF THE CARDIOVASCULAR SYSTEM DYNAMICS IN WOMEN WORKING AT THE NAVOI SILKWORM PLANT AND THE RISK OF DEVELOPING PRE-PATHOLIC CONDITIONS by Iskandarov Aziz Bakhromovich (2022) - Keywords: silkworm production, working conditions, cardiovascular system. One of the largest silkworm productions in Uzbekistan is the Navoi silkworm plant, where within the grant project ATSS-24.6 Development of new methodology of forecasting and prevention of professionally caused pre- pathological conditions at women working at agricultural silkworm productions of Uzbekistan, the studies on working conditions and their influence on the functional condition of different systems of the organism, including the cardiovascular system, were conducted. Keywords: conditions; pressure; production; silkworm; system; working
• INFLUENCE OF WORKING CONDITIONS IN UZBEK SILKWORM PLANTS ON THE FUNCTIONAL STATE OF THE BODY OF WOMEN by Iskandarov Aziz Bakhromovich (2022) - Internet address: http://artofmedicineimsj.us E-mail: info@artofmedicineimsj.us 11931 Barlow Pl Philadelphia, PA 19116, USA +1 (929) 266-0862 Art of Medicine Volume-2 International Medical Scientific Journal Issue-1 10.5281/zenodo.5847906 13 Influence of working conditions in uzbek silkworm plants on the functional state of the body of women Iskandarov Aziz Bakhromovich Doctor of Philosophy (Ph.D.) in Medical Sciences, Senior Researcher of the Scientific Research Institute of Sanitation, Hygiene and Occupational Diseases of the Ministry of Health of the Republic of Uzbekistan Keywords: silkworm production, working conditions, functional state of the body, fatigue, prevention. Keywords: butterflies; cocoons; conditions; production; silkworm; women; working

• EFFECTS OF INTENSIVE HYPOGLYCEMIC THERAPY FROM THE POSITION OF THEIR INFLUENCE ON THE DEVELOPMENT OF HEART RHYTHM DISORDERS by Mirzarahimova , Z. H.; Rakhimova , G.N.; Mullabaeva , G. U.; Yakubov , A. A. (2021) - However, a number of studies have shown that despite improved glycemic control, macrovascular complications and associated CVDs continue to progress in DM2 patients (UKPDS, Kumanato Study) Glycemic control studies have shown that intensive glycemic control in the two types of diabetes does not always have similar effects. In the works of Z.H. Lu et al., high levels of HbA1 were associated with increased risk of atrial fibrillation recurrence in patients with type 2 DM and paroxysmal AF who underwent catheter ablation Keywords: control; development; diabetes; hypoglycemia; patients; risk; study; type
• SAFETY OF INSULIN DEGLUDEC/INSULIN ASPART IN PATIENTS WITH DIABETES MELLITUS OVER A PERIOD OF 1 YEAR DURING ROUTINE CLINICAL CARE IN INDIA: SMART (STUDY OF MANAGEMENT OF DIABETES WITH RYZODEG™ TREATMENT) by Basu, D.; Kumar, H. (2021) - Patients previously on IDegAsp therapy or those participating in another study were excluded. Thirty adverse events were reported in 23 patients (2.2%) during the follow-up: two adverse events in two patients were serious with fatal outcomes, which were unrelated to IDegAsp use. Keywords: diabetes; idegasp; insulin; months; patients; study

• CLINICAL MANIFESTATION OF IRRITABLE BOWEL SYNDROME by Makhmudova L.I.; Akhmedova N.Sh.; Ergashov B.B. (2021) - In case of non-refractory IBS, the total length of symptoms over the past year to the present appeal to the doctor was an average of 11.14 ± 0.29 weeks, a positive effect was observed from the therapy appointed in accordance with the clinical recommendations of the bomb. With refractory IBS, the total duration of symptoms over the past year to the present appeal to the doctor was an average of 29.81 ± 0.27 weeks, there was a low effectiveness of the therapy appointed in accordance with the clinical recommendations of BRMMC, with a confirmed diagnosis of IBS and sufficient adherence to treatment. Keywords: ibs; ibsn; ibsr; patients; refractory

• FEATURES OF CHANGE OF MICROELEMENTAL COMPOSITION IN ANEMIA OF CHRONIC DISEASES IN ELDERLY AND OLD AGE by Boltaev Kamol Zhumaevich (2021) - Art of Medicine Volume-1 International Medical Scientific Journal Issue-2 10.5281/zenodo.5080556 39 This tendency persisted in elderly people, with the following differences: firstly, the indicators of IDA and ACD significantly differed among themselves, the increase was in favor of ACD; secondly, the combined occurrence of IDA and ACD was sharply increased in relation to individual IDA and ACD (3.30 and 1.50 times, respectively, P <0.001); thirdly, the number of patients with the combined occurrence of IDA and ACD was greater than that of IDA and ACD instead of those taken. It should be emphasized that the number of elderly patients with a combined occurrence of IDA + ACD was higher than IDA and ACD, instead of 8.46% (n = 33) versus 8.2% (n = 32). Keywords: acd; ida; patients; relation

• CLINICAL AND RADIOLOGICAL ASSESSMENT OF THE DENTAL IMPLANTATION TECHNIQUE IN PATIENTS WITH COMPLETE ABSENCE OF TEETH USING THE DICOM PROGRAM by Dustmatov J.E.; Makhkamova F.T.; Gulyamov S.S. (2021) - A method of quantifying overall satisfaction of complete denture patients / Y. Sato The low quality of life of patients, especially those with complete loss of teeth, against the background of a relatively high frequency of complications that occur after the installation of dental implants, confirms the postulate that there is still a shortage of methods with a high efficiency of choice of tactics and sequence of orthopedic treatment of this pathology, indicating on the relevance of this study. Keywords: implants; patients; vol

• FREQUENCY OF OBSERVATION OF ANXIETY AND DEPRESSION IN THE DIAGNOSIS OF PRIMARY HEADACHES by Akhmedova Dilafruz Bahodirovna (2021) - According to the World Health Organization, three quarters of Art of Medicine Volume-1 International Medical Scientific Journal Issue-2 10.5281/zenodo.5552262 167 the population aged 18 to 65 experience a headache attack at least once in the last year, while chronic stress headaches occur in 2-3% of the population (Belimova L.N., 2016). Episodic stress headaches are not a serious medical or social problem, while chronic stress headaches are accompanied by various comorbid disorders (depression, sleep disturbances, somatoform disorders) that significantly impair the patient's daily life and quality of life. Keywords: depression; headaches; patients

• HISTOLOGICAL STRUCTURE OF THE RAT SPLEEN IN EARLY POSTNATAL ONTOGENESIS by Dilnoza Akhrorovna Khasanova (2021) - The distance between the marginal zone of the LF was on average 24.6 ± 0.15 microns, the distance between the germinal centers is on average 42.1 ± 0.19 microns The study of the trabecular vessels of newborn rats in the proximal part showed that the thickness of the venous wall averaged 3.13±0.37 microns, the inner diameter of the vein was on average 5.8±0.1 microns, the thickness of the artery wall averaged 4.3±0.07, the inner diameter of the artery was on average -5.0±0.12. The width of the germinal center of 11-day-old rats was on average 68.1±0.2 microns, and the periarterial zone was on average 35.8±0.4 microns. Keywords: average; microns; thickness; wall thickness

• THE IMPORTANCE OF THE CRITERIA OF SYSTEMIC INFLAMMATORY RESPONCE SYNDROME OF EARLY DIAGNOSTICS AND DETECTION OF BLOODSTREAM INFECTIONS by Akhmedova Dilshoda Rakhmanberdievna; Abdukhalilova Gulnora Kudratullaevna; Otamuratova Nargiza Khasandjanovna; Tadjieva Nigora Ubaidullaevna; Bektimirov Amir Mangu-Temirovich; Akhmedov Ildar Farrukovich; Tadjiev Batyr Mirkhashimovich (2021) - 0,0% 50,0% 100,0% 6,8% 3,8% 4,2% 20,0% 3,5% 5,7% 9,3% 33,3% 5,3% 5,0% 4,4% 3,2% 1,8% 11,4% 25,6% 3,2% 23,5% 9,5% 28,4% 66,7% 50,9% 8,6% 22,6% 100,0% 69,5% 0,4% 22,2% 1,1% 2,3% 0,3% 4,4% 1,8% 2,9% 1,3% Hyperthermia, tachycardia, leukocytosis, neutrophilia hyperthermia, tachycardia tachypnoea, leukocytosis hyperthermia, tachycardia tachypnoea Hyperthermia, tachycardia, leucocytosis 0,0% 50,0% 100,0% 42,1% 8,9% 25,3% 6,7% 8,8% 28,6% 14,0% 33,3% 9,5% 17,6% 30,4% 34,7% 28,1% 31,4% 19,6% 33,3% 7,4% 0,3% 3,8% 1,1% 1,8% 8,6% 2,0% 0,0% 2,1% 0,1% 4,4% 2,9% Hyperthermia + tachycardia Hyperthermia+leukocytosis Hyperthermia+tachypnoea Art of Medicine Volume-1 International Medical Scientific Journal Issue-2 10.5281/zenodo.5558714 185 Fig. Keywords: criteria; hyperthermia; patients; sirs; symptoms; tachycardia; years

• MEDIEVAL METALWORKING CRAFTS OF KHOREZM IN THE SOURCES by Turganov Baxit Qurbanbaevich; Reimbayev Rustem Sarsenbayevich; Keranova Aigul Kuandykovna (2021) - The tradition of covering jewelry, various dishes, weapons and other objects with gold and silver by Khorezm craftsmen continued in the XIII and XIV centuries. This is due to the fact that from the early Middle Ages to the late Middle Ages, silver coins and ingots, silver vessels of Eastern countries such as Central Asia, China, India, Iran, were among the goods exported to the markets of Eastern Europe through Khorezm merchants. Keywords: century; cities; ibn; khorezm; products; silver; trade; urgench

• EFFECTS OF BLOOD PRESSURE GOALS ON CARDIOVASCULAR OUTCOMES IN HYPERTENSIVE PATIENTS by Stephan James (2021) - Visualnya Mirip Smoke Screen Mahjong Wins 3 Pola Konsumsi Warga Berubah Akibat Krisis Efeknya Seperti Adaptive Mode Mahjong Ways 2 Gangguan Pasar Picu Kepanikan Massal Situasinya Seperti Panic Spin Mahjong Wins Wilayah Pertanian Alami Penurunan Produksi Polanya Mirip Weak Hit Mahjong Ways 3 Cuaca Ekstrem Ganggu Jalur Darat Alurnya Mirip Blocked Path Mahjong Wins 2 Aktivitas Laut Tak Normal Terpantau Geraknya Mirip Wave Pattern Mahjong Ways Lonjakan Biaya Hidup Jadi Sorotan Ritmenya Seperti Cost Up Spin Mahjong Wins Lokal Menguat Polanya Steady Spin Mahjong Wins 3 Harga Komoditas Bergerak Fluktuatif Volatilitas Tinggi Ala Mahjong Ways Konsumsi Rumah Tangga Stabil di Tengah Tekanan Ketahanan Mahjong Wins Arus Belanja Online Meningkat Tajam Lonjakan Seperti Progressive Win Mahjong Ways 2 Pasar Regional Tunjukkan Tanda Konsolidasi Polanya Reset Board Mahjong Wins 3 Kemacetan Panjang Terjadi di Jam Sibuk Kepadatan Full Reel Mahjong Ways Pengaturan Lalu Lintas Keywords: akhir; aktif; aktivitas; alurnya; alurnya mirip; alurnya seperti; analisis; area; awal; baru; bergerak; bertahap; beruntun; board mahjong; bonus mahjong; cepat; cuaca; dampaknya; dan; dari; data; di mahjong; digital; dinamikanya; distribusi; efeknya; efeknya mirip; efeknya seperti; fase; feature mahjong; fenomena; gangguan; harga; harian; hujan; jalur; jam; kembali; kemenangan; kepadatan; kombinasi; kombinasi mahjong; konsisten; lebih; lingkungan; lokal; lonjakan; mahjong ways; malam; masuk; mengarah; meningkat; menunjukkan; mirip; mirip mahjong; mirip mode; mode mahjong; mulai; multiplier; muncul; naik; panjang; pasar; pemantauan; perubahan; pgsoft; picu; pola mahjong; polanya; polanya mirip; polanya seperti; prosesnya; publik; putaran; reel mahjong; ritmenya; ritmenya mirip; ritmenya seperti; rtp; saat; scatter mahjong; seperti; seperti mahjong; serupa; shift mahjong; simbol; simbol mahjong; sistem; situasinya; situasinya seperti; skemanya; slot; spin mahjong; stabil; statistik; tak; tekanan; terjadi; terlihat; terpantau; tile; tinggi; transportasi; tren; tumble; tumble mahjong; ways cuaca; ways masuk; ways mengarah; ways mulai; wilayah; wild; wild mahjong; wins; wins aktivitas; yang; zona

• FEATURES OF THE EPISODIC PROCESS IN THE TERRITORY OF NATURAL FOCUSES OF THE PLAGUE OF THE CIS COUNTRIES by Dmitriev A.N.; Nematov A.S.; Rakhmanova D.A. (2022) - In the conditions of mountainous and high-altitude landscapes, the impact of modern climate warming on the state of parasitic systems of the mountain and high- altitude natural plague foci is less pronounced. Keywords: epizootic activity, natural plague focus, Central Kyzylkum, giant gerbil, Y. pestis. Keywords: foci; pestispestis; plague; republic; territory

• NEONATAL RESUSCITATION IN 22-WEEK PREGNANCIES by Basu, D. ; Kumar, H. (2022) - P<0.05).3 A report from a hospital in Iowa in which active resuscitation was offered for all infants born at 22 to 23 weeks’ gestation showed that 70% of the infants born at 22 weeks survived and 55% of these patients had no or only mild neurodevelopmental impairment at follow-up.4 A cohort study of Swedish infants born at 22 to 24 weeks’ gestation showed that 52% of the infants born at 22 weeks’ gestation survived, with 50% of the survivors having no neurodevelopmental impairment at 2.5 years of age, outcomes that mirrored those in infants born at 23 to 24 weeks.5 In pediatric cardiology practices, the survival rate of 30 to 70% among patients who require extracorporeal life support is considered reasonable for initiating that form of invasive therapy, so it certainly appears from the available data that birth at 22 weeks’ gestation with resuscitation for all neonates also meets this mark.6 The earliest gestational age at birth after which survival is possible has decreased incrementally over time. P<0.05).3 A report from a hospital in Iowa in which active resuscitation was offered for all infants born at 22 to 23 weeks’ gestation showed that 70% of the infants born at 22 weeks survived and 55% of these patients had no or only mild neurodevelopmental impairment at follow-up.4 A cohort study of Swedish infants born at 22 to 24 weeks’ gestation showed that 52% of the infants born at 22 weeks’ gestation survived, with 50% of the survivors having no neurodevelopmental impairment at 2.5 years of age, outcomes that mirrored those in infants born at 23 to 24 weeks.5 In pediatric cardiology practices, the survival rate of 30 to 70% among patients who require extracorporeal life support is considered reasonable for initiating that form of invasive therapy, so it certainly appears from the available data that birth at 22 weeks’ gestation with resuscitation for all neonates also meets this mark.6. Keywords: approach; care; gestation; infants; resuscitation; weeks

Epilogue

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Created: 2025-12-22