id	sid	tid	token	lemma	pos
asodahs-27	1	1	ahirwar	ahirwar	NOUN
asodahs-27	1	2	et	et	PROPN
asodahs-27	1	3	al	al	PROPN
asodahs-27	1	4	asian	asian	PROPN
asodahs-27	1	5	journal	journal	PROPN
asodahs-27	1	6	of	of	ADP
asodahs-27	1	7	dental	dental	ADJ
asodahs-27	1	8	and	and	CCONJ
asodahs-27	1	9	health	health	NOUN
asodahs-27	1	10	sciences	science	NOUN
asodahs-27	1	11	.	.	PUNCT
asodahs-27	1	12	2022	2022	NUM
asodahs-27	1	13	;	;	PUNCT
asodahs-27	1	14	2(4):59	2(4):59	NUM
asodahs-27	1	15	-	-	SYM
asodahs-27	1	16	63	63	NUM
asodahs-27	2	1	[	[	X
asodahs-27	2	2	59	59	NUM
asodahs-27	2	3	]	]	PUNCT
asodahs-27	2	4	ajdhs.com	ajdhs.com	X
asodahs-27	2	5	available	available	ADJ
asodahs-27	2	6	online	online	ADV
asodahs-27	2	7	at	at	ADP
asodahs-27	2	8	ajdhs.com	ajdhs.com	X
asodahs-27	2	9	asian	asian	ADJ
asodahs-27	2	10	journal	journal	NOUN
asodahs-27	2	11	of	of	ADP
asodahs-27	2	12	dental	dental	ADJ
asodahs-27	2	13	and	and	CCONJ
asodahs-27	2	14	health	health	NOUN
asodahs-27	2	15	sciences	science	NOUN
asodahs-27	2	16	open	open	VERB
asodahs-27	2	17	access	access	NOUN
asodahs-27	2	18	to	to	ADP
asodahs-27	2	19	pharmaceutical	pharmaceutical	NOUN
asodahs-27	2	20	and	and	CCONJ
asodahs-27	2	21	medical	medical	ADJ
asodahs-27	2	22	research	research	NOUN
asodahs-27	2	23	copyright	copyright	NOUN
asodahs-27	2	24	©	©	ADP
asodahs-27	2	25	2022	2022	NUM
asodahs-27	2	26	the	the	DET
asodahs-27	2	27	author(s	author(s	NOUN
asodahs-27	2	28	):	):	PUNCT
asodahs-27	2	29	this	this	PRON
asodahs-27	2	30	is	be	AUX
asodahs-27	2	31	an	an	DET
asodahs-27	2	32	open	open	ADJ
asodahs-27	2	33	-	-	PUNCT
asodahs-27	2	34	access	access	NOUN
asodahs-27	2	35	article	article	NOUN
asodahs-27	2	36	distributed	distribute	VERB
asodahs-27	2	37	under	under	ADP
asodahs-27	2	38	the	the	DET
asodahs-27	2	39	terms	term	NOUN
asodahs-27	2	40	of	of	ADP
asodahs-27	2	41	the	the	DET
asodahs-27	2	42	cc	cc	PROPN
asodahs-27	2	43	by	by	ADP
asodahs-27	2	44	-	-	PUNCT
asodahs-27	2	45	nc	nc	PROPN
asodahs-27	2	46	4.0	4.0	NUM
asodahs-27	2	47	which	which	PRON
asodahs-27	2	48	permits	permit	VERB
asodahs-27	2	49	unrestricted	unrestricted	ADJ
asodahs-27	2	50	use	use	NOUN
asodahs-27	2	51	,	,	PUNCT
asodahs-27	2	52	distribution	distribution	NOUN
asodahs-27	2	53	,	,	PUNCT
asodahs-27	2	54	and	and	CCONJ
asodahs-27	2	55	reproduction	reproduction	NOUN
asodahs-27	2	56	in	in	ADP
asodahs-27	2	57	any	any	DET
asodahs-27	2	58	medium	medium	NOUN
asodahs-27	2	59	for	for	ADP
asodahs-27	2	60	non	non	ADJ
asodahs-27	2	61	-	-	ADJ
asodahs-27	2	62	commercial	commercial	ADJ
asodahs-27	2	63	use	use	NOUN
asodahs-27	2	64	provided	provide	VERB
asodahs-27	2	65	the	the	DET
asodahs-27	2	66	original	original	ADJ
asodahs-27	2	67	author	author	NOUN
asodahs-27	2	68	and	and	CCONJ
asodahs-27	2	69	source	source	NOUN
asodahs-27	2	70	are	be	AUX
asodahs-27	2	71	credited	credit	VERB
asodahs-27	2	72	review	review	NOUN
asodahs-27	2	73	on	on	ADP
asodahs-27	2	74	qsar	qsar	NOUN
asodahs-27	2	75	using	use	VERB
asodahs-27	2	76	anticancer	anticancer	NOUN
asodahs-27	2	77	drug	drug	PROPN
asodahs-27	2	78	hemant	hemant	PROPN
asodahs-27	2	79	ahirwar	ahirwar	PROPN
asodahs-27	2	80	,	,	PUNCT
asodahs-27	2	81	gabbar	gabbar	ADJ
asodahs-27	2	82	kurmi	kurmi	PROPN
asodahs-27	2	83	,	,	PUNCT
asodahs-27	2	84	rubeena	rubeena	PROPN
asodahs-27	2	85	khan	khan	PROPN
asodahs-27	2	86	,	,	PUNCT
asodahs-27	2	87	basant	basant	PROPN
asodahs-27	2	88	khare	khare	PROPN
asodahs-27	2	89	,	,	PUNCT
asodahs-27	2	90	anushree	anushree	ADJ
asodahs-27	2	91	jain	jain	NOUN
asodahs-27	2	92	,	,	PUNCT
asodahs-27	2	93	prateek	prateek	PROPN
asodahs-27	2	94	kumar	kumar	PROPN
asodahs-27	2	95	jain	jain	PROPN
asodahs-27	2	96	,	,	PUNCT
asodahs-27	2	97	bhupendra	bhupendra	PROPN
asodahs-27	2	98	singh	singh	PROPN
asodahs-27	2	99	thakur	thakur	PROPN
asodahs-27	2	100	*	*	PROPN
asodahs-27	2	101	adina	adina	PROPN
asodahs-27	2	102	college	college	PROPN
asodahs-27	2	103	of	of	ADP
asodahs-27	2	104	pharmacy	pharmacy	PROPN
asodahs-27	2	105	,	,	PUNCT
asodahs-27	2	106	adina	adina	PROPN
asodahs-27	2	107	campus	campus	PROPN
asodahs-27	2	108	rd	rd	PROPN
asodahs-27	2	109	,	,	PUNCT
asodahs-27	2	110	lahdara	lahdara	PROPN
asodahs-27	2	111	,	,	PUNCT
asodahs-27	2	112	sagar	sagar	PROPN
asodahs-27	2	113	,	,	PUNCT
asodahs-27	2	114	mp	mp	PROPN
asodahs-27	2	115	,	,	PUNCT
asodahs-27	2	116	470001	470001	NUM
asodahs-27	2	117	article	article	NOUN
asodahs-27	2	118	info	info	NOUN
asodahs-27	2	119	:	:	PUNCT
asodahs-27	3	1	_	_	PUNCT
asodahs-27	4	1	_	_	PUNCT
asodahs-27	5	1	_	_	PUNCT
asodahs-27	6	1	_	_	PUNCT
asodahs-27	7	1	_	_	PUNCT
asodahs-27	8	1	_	_	PUNCT
asodahs-27	9	1	_	_	PUNCT
asodahs-27	10	1	_	_	PUNCT
asodahs-27	11	1	_	_	PUNCT
asodahs-27	12	1	_	_	PUNCT
asodahs-27	13	1	_	_	PUNCT
asodahs-27	14	1	_	_	PUNCT
asodahs-27	15	1	_	_	PUNCT
asodahs-27	16	1	_	_	PUNCT
asodahs-27	17	1	_	_	PUNCT
asodahs-27	18	1	_	_	PUNCT
asodahs-27	19	1	_	_	PUNCT
asodahs-27	20	1	_	_	PUNCT
asodahs-27	21	1	_	_	PUNCT
asodahs-27	22	1	_	_	PUNCT
asodahs-27	23	1	_	_	PUNCT
asodahs-27	24	1	_	_	PUNCT
asodahs-27	25	1	_	_	PUNCT
asodahs-27	26	1	_	_	PUNCT
asodahs-27	27	1	_	_	PUNCT
asodahs-27	28	1	_	_	PUNCT
asodahs-27	29	1	_	_	PUNCT
asodahs-27	30	1	_	_	PUNCT
asodahs-27	31	1	_	_	PUNCT
asodahs-27	32	1	_	_	PUNCT
asodahs-27	33	1	_	_	PUNCT
asodahs-27	34	1	_	_	PUNCT
asodahs-27	35	1	_	_	PUNCT
asodahs-27	36	1	_	_	PUNCT
asodahs-27	37	1	_	_	PUNCT
asodahs-27	38	1	_	_	PUNCT
asodahs-27	39	1	_	_	PUNCT
asodahs-27	40	1	_	_	PUNCT
asodahs-27	41	1	_	_	PUNCT
asodahs-27	41	2	article	article	NOUN
asodahs-27	41	3	history	history	NOUN
asodahs-27	41	4	:	:	PUNCT
asodahs-27	41	5	received	receive	VERB
asodahs-27	41	6	17	17	NUM
asodahs-27	41	7	sep	sep	NOUN
asodahs-27	41	8	2022	2022	NUM
asodahs-27	41	9	reviewed	review	VERB
asodahs-27	41	10	09	09	NUM
asodahs-27	41	11	nov	nov	NOUN
asodahs-27	41	12	2022	2022	NUM
asodahs-27	41	13	accepted	accept	VERB
asodahs-27	41	14	24	24	NUM
asodahs-27	41	15	nov	nov	NOUN
asodahs-27	41	16	2022	2022	NUM
asodahs-27	41	17	published	publish	VERB
asodahs-27	41	18	15	15	NUM
asodahs-27	41	19	dec	dec	PROPN
asodahs-27	41	20	2022	2022	NUM
asodahs-27	41	21	_	_	PUNCT
asodahs-27	42	1	_	_	PUNCT
asodahs-27	43	1	_	_	PUNCT
asodahs-27	44	1	_	_	PUNCT
asodahs-27	45	1	_	_	PUNCT
asodahs-27	46	1	_	_	PUNCT
asodahs-27	47	1	_	_	PUNCT
asodahs-27	48	1	_	_	PUNCT
asodahs-27	49	1	_	_	PUNCT
asodahs-27	50	1	_	_	PUNCT
asodahs-27	51	1	_	_	PUNCT
asodahs-27	52	1	_	_	PUNCT
asodahs-27	53	1	_	_	PUNCT
asodahs-27	54	1	_	_	PUNCT
asodahs-27	55	1	_	_	PUNCT
asodahs-27	56	1	_	_	PUNCT
asodahs-27	57	1	_	_	PUNCT
asodahs-27	58	1	_	_	PUNCT
asodahs-27	59	1	_	_	PUNCT
asodahs-27	60	1	_	_	PUNCT
asodahs-27	61	1	_	_	PUNCT
asodahs-27	62	1	_	_	PUNCT
asodahs-27	63	1	_	_	PUNCT
asodahs-27	64	1	_	_	PUNCT
asodahs-27	65	1	_	_	PUNCT
asodahs-27	66	1	_	_	PUNCT
asodahs-27	67	1	_	_	PUNCT
asodahs-27	68	1	_	_	PUNCT
asodahs-27	69	1	_	_	PUNCT
asodahs-27	70	1	_	_	PUNCT
asodahs-27	71	1	_	_	PUNCT
asodahs-27	72	1	_	_	PUNCT
asodahs-27	73	1	_	_	PUNCT
asodahs-27	74	1	_	_	PUNCT
asodahs-27	75	1	_	_	PUNCT
asodahs-27	76	1	_	_	PUNCT
asodahs-27	77	1	_	_	PUNCT
asodahs-27	78	1	_	_	PUNCT
asodahs-27	79	1	_	_	PUNCT
asodahs-27	79	2	cite	cite	VERB
asodahs-27	79	3	this	this	DET
asodahs-27	79	4	article	article	NOUN
asodahs-27	79	5	as	as	ADP
asodahs-27	79	6	:	:	PUNCT
asodahs-27	79	7	ahirwar	ahirwar	PROPN
asodahs-27	79	8	h	h	PROPN
asodahs-27	79	9	,	,	PUNCT
asodahs-27	79	10	kurmi	kurmi	PROPN
asodahs-27	79	11	g	g	PROPN
asodahs-27	79	12	,	,	PUNCT
asodahs-27	79	13	khan	khan	PROPN
asodahs-27	79	14	r	r	PROPN
asodahs-27	79	15	,	,	PUNCT
asodahs-27	79	16	khare	khare	PROPN
asodahs-27	79	17	b	b	PROPN
asodahs-27	79	18	,	,	PUNCT
asodahs-27	79	19	jain	jain	PROPN
asodahs-27	79	20	a	a	PRON
asodahs-27	79	21	,	,	PUNCT
asodahs-27	79	22	jain	jain	PROPN
asodahs-27	79	23	pk	pk	PROPN
asodahs-27	79	24	,	,	PUNCT
asodahs-27	79	25	thakur	thakur	PROPN
asodahs-27	79	26	bs	bs	PROPN
asodahs-27	79	27	,	,	PUNCT
asodahs-27	79	28	review	review	NOUN
asodahs-27	79	29	on	on	ADP
asodahs-27	79	30	qsar	qsar	NOUN
asodahs-27	79	31	using	use	VERB
asodahs-27	79	32	anticancer	anticancer	NOUN
asodahs-27	79	33	drug	drug	NOUN
asodahs-27	79	34	,	,	PUNCT
asodahs-27	79	35	asian	asian	ADJ
asodahs-27	79	36	journal	journal	NOUN
asodahs-27	79	37	of	of	ADP
asodahs-27	79	38	dental	dental	ADJ
asodahs-27	79	39	and	and	CCONJ
asodahs-27	79	40	health	health	NOUN
asodahs-27	79	41	sciences	science	NOUN
asodahs-27	79	42	.	.	PUNCT
asodahs-27	79	43	2022	2022	NUM
asodahs-27	79	44	;	;	PUNCT
asodahs-27	79	45	2(4):59	2(4):59	NUM
asodahs-27	79	46	-	-	SYM
asodahs-27	79	47	63	63	NUM
asodahs-27	79	48	doi	doi	NOUN
asodahs-27	79	49	:	:	PUNCT
asodahs-27	79	50	http://dx.doi.org/10.22270/ajdhs.v2i4.27	http://dx.doi.org/10.22270/ajdhs.v2i4.27	X
asodahs-27	79	51	_	_	PUNCT
asodahs-27	79	52	_	_	PUNCT
asodahs-27	80	1	_	_	PUNCT
asodahs-27	81	1	_	_	PUNCT
asodahs-27	82	1	_	_	PUNCT
asodahs-27	83	1	_	_	PUNCT
asodahs-27	84	1	_	_	PUNCT
asodahs-27	85	1	_	_	PUNCT
asodahs-27	86	1	_	_	PUNCT
asodahs-27	87	1	_	_	PUNCT
asodahs-27	88	1	_	_	PUNCT
asodahs-27	89	1	_	_	PUNCT
asodahs-27	90	1	_	_	PUNCT
asodahs-27	91	1	_	_	PUNCT
asodahs-27	92	1	_	_	PUNCT
asodahs-27	93	1	_	_	PUNCT
asodahs-27	94	1	_	_	PUNCT
asodahs-27	95	1	_	_	PUNCT
asodahs-27	96	1	_	_	PUNCT
asodahs-27	97	1	_	_	PUNCT
asodahs-27	98	1	_	_	PUNCT
asodahs-27	99	1	_	_	PUNCT
asodahs-27	100	1	_	_	PUNCT
asodahs-27	101	1	_	_	PUNCT
asodahs-27	102	1	_	_	PUNCT
asodahs-27	103	1	_	_	PUNCT
asodahs-27	104	1	_	_	PUNCT
asodahs-27	105	1	_	_	PUNCT
asodahs-27	106	1	_	_	PUNCT
asodahs-27	107	1	_	_	PUNCT
asodahs-27	108	1	_	_	PUNCT
asodahs-27	109	1	_	_	PUNCT
asodahs-27	110	1	_	_	PUNCT
asodahs-27	111	1	_	_	PUNCT
asodahs-27	112	1	_	_	PUNCT
asodahs-27	113	1	_	_	PUNCT
asodahs-27	114	1	_	_	PUNCT
asodahs-27	115	1	_	_	PUNCT
asodahs-27	116	1	_	_	PUNCT
asodahs-27	117	1	*	*	PUNCT
asodahs-27	117	2	address	address	NOUN
asodahs-27	117	3	for	for	ADP
asodahs-27	117	4	correspondence	correspondence	NOUN
asodahs-27	117	5	:	:	PUNCT
asodahs-27	117	6	bhupendra	bhupendra	PROPN
asodahs-27	117	7	singh	singh	PROPN
asodahs-27	117	8	thakur	thakur	PROPN
asodahs-27	117	9	,	,	PUNCT
asodahs-27	117	10	adina	adina	PROPN
asodahs-27	117	11	college	college	PROPN
asodahs-27	117	12	of	of	ADP
asodahs-27	117	13	pharmacy	pharmacy	PROPN
asodahs-27	117	14	,	,	PUNCT
asodahs-27	117	15	adina	adina	PROPN
asodahs-27	117	16	campus	campus	PROPN
asodahs-27	117	17	rd	rd	PROPN
asodahs-27	117	18	,	,	PUNCT
asodahs-27	117	19	lahdara	lahdara	PROPN
asodahs-27	117	20	,	,	PUNCT
asodahs-27	117	21	sagar	sagar	PROPN
asodahs-27	117	22	,	,	PUNCT
asodahs-27	117	23	mp	mp	PROPN
asodahs-27	117	24	,	,	PUNCT
asodahs-27	117	25	470001	470001	NUM
asodahs-27	117	26	abstract	abstract	ADJ
asodahs-27	117	27	_	_	PUNCT
asodahs-27	118	1	_	_	PUNCT
asodahs-27	119	1	_	_	PUNCT
asodahs-27	120	1	_	_	PUNCT
asodahs-27	121	1	_	_	PUNCT
asodahs-27	122	1	_	_	PUNCT
asodahs-27	123	1	_	_	PUNCT
asodahs-27	124	1	_	_	PUNCT
asodahs-27	125	1	_	_	PUNCT
asodahs-27	126	1	_	_	PUNCT
asodahs-27	127	1	_	_	PUNCT
asodahs-27	128	1	_	_	PUNCT
asodahs-27	129	1	_	_	PUNCT
asodahs-27	130	1	_	_	PUNCT
asodahs-27	131	1	_	_	PUNCT
asodahs-27	132	1	_	_	PUNCT
asodahs-27	133	1	_	_	PUNCT
asodahs-27	134	1	_	_	PUNCT
asodahs-27	135	1	_	_	PUNCT
asodahs-27	136	1	_	_	PUNCT
asodahs-27	137	1	_	_	PUNCT
asodahs-27	138	1	_	_	PUNCT
asodahs-27	139	1	_	_	PUNCT
asodahs-27	140	1	_	_	PUNCT
asodahs-27	141	1	_	_	PUNCT
asodahs-27	142	1	_	_	PUNCT
asodahs-27	143	1	_	_	PUNCT
asodahs-27	144	1	_	_	PUNCT
asodahs-27	145	1	_	_	PUNCT
asodahs-27	146	1	_	_	PUNCT
asodahs-27	147	1	_	_	PUNCT
asodahs-27	148	1	_	_	PUNCT
asodahs-27	149	1	_	_	PUNCT
asodahs-27	150	1	_	_	PUNCT
asodahs-27	151	1	_	_	PUNCT
asodahs-27	152	1	_	_	PUNCT
asodahs-27	153	1	_	_	PUNCT
asodahs-27	154	1	_	_	PUNCT
asodahs-27	155	1	_	_	PUNCT
asodahs-27	156	1	_	_	PUNCT
asodahs-27	157	1	_	_	PUNCT
asodahs-27	158	1	_	_	PUNCT
asodahs-27	159	1	_	_	PUNCT
asodahs-27	160	1	_	_	PUNCT
asodahs-27	161	1	_	_	PUNCT
asodahs-27	162	1	_	_	PUNCT
asodahs-27	163	1	_	_	PUNCT
asodahs-27	164	1	_	_	PUNCT
asodahs-27	165	1	_	_	PUNCT
asodahs-27	166	1	_	_	PUNCT
asodahs-27	167	1	_	_	PUNCT
asodahs-27	168	1	_	_	PUNCT
asodahs-27	169	1	_	_	PUNCT
asodahs-27	170	1	_	_	PUNCT
asodahs-27	171	1	_	_	PUNCT
asodahs-27	172	1	_	_	PUNCT
asodahs-27	173	1	_	_	PUNCT
asodahs-27	174	1	_	_	PUNCT
asodahs-27	175	1	_	_	PUNCT
asodahs-27	176	1	_	_	PUNCT
asodahs-27	177	1	_	_	PUNCT
asodahs-27	178	1	_	_	PUNCT
asodahs-27	179	1	_	_	PUNCT
asodahs-27	180	1	_	_	PUNCT
asodahs-27	181	1	_	_	PUNCT
asodahs-27	182	1	_	_	PUNCT
asodahs-27	183	1	_	_	PUNCT
asodahs-27	184	1	_	_	PUNCT
asodahs-27	185	1	_	_	PUNCT
asodahs-27	186	1	_	_	PUNCT
asodahs-27	187	1	_	_	PUNCT
asodahs-27	188	1	_	_	PUNCT
asodahs-27	189	1	_	_	PUNCT
asodahs-27	190	1	_	_	PUNCT
asodahs-27	191	1	_	_	PUNCT
asodahs-27	192	1	_	_	PUNCT
asodahs-27	193	1	_	_	PUNCT
asodahs-27	194	1	_	_	PUNCT
asodahs-27	195	1	_	_	PUNCT
asodahs-27	196	1	_	_	PUNCT
asodahs-27	197	1	_	_	PUNCT
asodahs-27	198	1	_	_	PUNCT
asodahs-27	199	1	_	_	PUNCT
asodahs-27	200	1	_	_	PUNCT
asodahs-27	201	1	_	_	PUNCT
asodahs-27	202	1	_	_	PUNCT
asodahs-27	203	1	_	_	PUNCT
asodahs-27	204	1	_	_	PUNCT
asodahs-27	205	1	_	_	PUNCT
asodahs-27	206	1	_	_	PUNCT
asodahs-27	207	1	_	_	PUNCT
asodahs-27	208	1	_	_	PUNCT
asodahs-27	209	1	_	_	PUNCT
asodahs-27	210	1	_	_	PUNCT
asodahs-27	211	1	_	_	PUNCT
asodahs-27	212	1	_	_	PUNCT
asodahs-27	213	1	_	_	PUNCT
asodahs-27	214	1	_	_	PUNCT
asodahs-27	215	1	_	_	PUNCT
asodahs-27	216	1	_	_	PUNCT
asodahs-27	217	1	_	_	PUNCT
asodahs-27	218	1	_	_	PUNCT
asodahs-27	219	1	_	_	PUNCT
asodahs-27	220	1	_	_	PUNCT
asodahs-27	221	1	_	_	PUNCT
asodahs-27	222	1	_	_	PUNCT
asodahs-27	223	1	_	_	PUNCT
asodahs-27	224	1	_	_	PUNCT
asodahs-27	225	1	_	_	PUNCT
asodahs-27	226	1	_	_	PUNCT
asodahs-27	227	1	_	_	PUNCT
asodahs-27	228	1	_	_	PUNCT
asodahs-27	229	1	_	_	PUNCT
asodahs-27	230	1	_	_	PUNCT
asodahs-27	231	1	_	_	PUNCT
asodahs-27	232	1	new	new	ADJ
asodahs-27	232	2	drug	drug	NOUN
asodahs-27	232	3	discovery	discovery	NOUN
asodahs-27	232	4	has	have	AUX
asodahs-27	232	5	been	be	AUX
asodahs-27	232	6	acknowledged	acknowledge	VERB
asodahs-27	232	7	as	as	ADP
asodahs-27	232	8	a	a	DET
asodahs-27	232	9	complicated	complicated	ADJ
asodahs-27	232	10	,	,	PUNCT
asodahs-27	232	11	expensive	expensive	ADJ
asodahs-27	232	12	,	,	PUNCT
asodahs-27	232	13	time	time	NOUN
asodahs-27	232	14	-	-	PUNCT
asodahs-27	232	15	consuming	consume	VERB
asodahs-27	232	16	,	,	PUNCT
asodahs-27	232	17	and	and	CCONJ
asodahs-27	232	18	challenging	challenging	ADJ
asodahs-27	232	19	project	project	NOUN
asodahs-27	232	20	.	.	PUNCT
asodahs-27	233	1	it	it	PRON
asodahs-27	233	2	has	have	AUX
asodahs-27	233	3	been	be	AUX
asodahs-27	233	4	estimated	estimate	VERB
asodahs-27	233	5	that	that	SCONJ
asodahs-27	233	6	around	around	ADV
asodahs-27	233	7	12	12	NUM
asodahs-27	233	8	years	year	NOUN
asodahs-27	233	9	and	and	CCONJ
asodahs-27	233	10	2.7	2.7	NUM
asodahs-27	233	11	billion	billion	NUM
asodahs-27	233	12	usd	usd	NOUN
asodahs-27	233	13	,	,	PUNCT
asodahs-27	233	14	on	on	ADP
asodahs-27	233	15	average	average	ADJ
asodahs-27	233	16	,	,	PUNCT
asodahs-27	233	17	are	be	AUX
asodahs-27	233	18	demanded	demand	VERB
asodahs-27	233	19	for	for	ADP
asodahs-27	233	20	a	a	DET
asodahs-27	233	21	new	new	ADJ
asodahs-27	233	22	drug	drug	NOUN
asodahs-27	233	23	discovery	discovery	NOUN
asodahs-27	233	24	via	via	ADP
asodahs-27	233	25	traditional	traditional	ADJ
asodahs-27	233	26	drug	drug	NOUN
asodahs-27	233	27	development	development	NOUN
asodahs-27	233	28	pipeline	pipeline	NOUN
asodahs-27	233	29	.	.	PUNCT
asodahs-27	234	1	how	how	SCONJ
asodahs-27	234	2	to	to	PART
asodahs-27	234	3	reduce	reduce	VERB
asodahs-27	234	4	the	the	DET
asodahs-27	234	5	research	research	NOUN
asodahs-27	234	6	cost	cost	NOUN
asodahs-27	234	7	and	and	CCONJ
asodahs-27	234	8	speed	speed	VERB
asodahs-27	234	9	up	up	ADP
asodahs-27	234	10	the	the	DET
asodahs-27	234	11	development	development	NOUN
asodahs-27	234	12	process	process	NOUN
asodahs-27	234	13	of	of	ADP
asodahs-27	234	14	new	new	ADJ
asodahs-27	234	15	drug	drug	NOUN
asodahs-27	234	16	discovery	discovery	NOUN
asodahs-27	234	17	has	have	AUX
asodahs-27	234	18	become	become	VERB
asodahs-27	234	19	a	a	DET
asodahs-27	234	20	challenging	challenging	ADJ
asodahs-27	234	21	,	,	PUNCT
asodahs-27	234	22	urgent	urgent	ADJ
asodahs-27	234	23	question	question	NOUN
asodahs-27	234	24	for	for	ADP
asodahs-27	234	25	the	the	DET
asodahs-27	234	26	pharmaceutical	pharmaceutical	ADJ
asodahs-27	234	27	industry	industry	NOUN
asodahs-27	234	28	.	.	PUNCT
asodahs-27	235	1	computer	computer	NOUN
asodahs-27	235	2	-	-	PUNCT
asodahs-27	235	3	aided	aid	VERB
asodahs-27	235	4	drug	drug	NOUN
asodahs-27	235	5	discovery	discovery	NOUN
asodahs-27	235	6	(	(	PUNCT
asodahs-27	235	7	cadd	cadd	NOUN
asodahs-27	235	8	)	)	PUNCT
asodahs-27	235	9	has	have	AUX
asodahs-27	235	10	emerged	emerge	VERB
asodahs-27	235	11	as	as	ADP
asodahs-27	235	12	a	a	DET
asodahs-27	235	13	powerful	powerful	ADJ
asodahs-27	235	14	and	and	CCONJ
asodahs-27	235	15	promising	promise	VERB
asodahs-27	235	16	technology	technology	NOUN
asodahs-27	235	17	for	for	ADP
asodahs-27	235	18	faster	fast	ADJ
asodahs-27	235	19	,	,	PUNCT
asodahs-27	235	20	cheaper	cheap	ADJ
asodahs-27	235	21	and	and	CCONJ
asodahs-27	235	22	more	more	ADV
asodahs-27	235	23	effective	effective	ADJ
asodahs-27	235	24	drug	drug	NOUN
asodahs-27	235	25	design	design	NOUN
asodahs-27	235	26	.	.	PUNCT
asodahs-27	236	1	recently	recently	ADV
asodahs-27	236	2	,	,	PUNCT
asodahs-27	236	3	the	the	DET
asodahs-27	236	4	rapid	rapid	ADJ
asodahs-27	236	5	growth	growth	NOUN
asodahs-27	236	6	of	of	ADP
asodahs-27	236	7	computational	computational	ADJ
asodahs-27	236	8	tools	tool	NOUN
asodahs-27	236	9	for	for	ADP
asodahs-27	236	10	drug	drug	NOUN
asodahs-27	236	11	discovery	discovery	NOUN
asodahs-27	236	12	,	,	PUNCT
asodahs-27	236	13	including	include	VERB
asodahs-27	236	14	anticancer	anticancer	NOUN
asodahs-27	236	15	therapies	therapy	NOUN
asodahs-27	236	16	,	,	PUNCT
asodahs-27	236	17	has	have	AUX
asodahs-27	236	18	exhibited	exhibit	VERB
asodahs-27	236	19	a	a	DET
asodahs-27	236	20	significant	significant	ADJ
asodahs-27	236	21	and	and	CCONJ
asodahs-27	236	22	outstanding	outstanding	ADJ
asodahs-27	236	23	impact	impact	NOUN
asodahs-27	236	24	on	on	ADP
asodahs-27	236	25	anticancer	anticancer	NOUN
asodahs-27	236	26	drug	drug	NOUN
asodahs-27	236	27	design	design	NOUN
asodahs-27	236	28	,	,	PUNCT
asodahs-27	236	29	and	and	CCONJ
asodahs-27	236	30	has	have	AUX
asodahs-27	236	31	also	also	ADV
asodahs-27	236	32	provided	provide	VERB
asodahs-27	236	33	fruitful	fruitful	ADJ
asodahs-27	236	34	insights	insight	NOUN
asodahs-27	236	35	into	into	ADP
asodahs-27	236	36	the	the	DET
asodahs-27	236	37	area	area	NOUN
asodahs-27	236	38	of	of	ADP
asodahs-27	236	39	cancer	cancer	NOUN
asodahs-27	236	40	therapy	therapy	NOUN
asodahs-27	236	41	.	.	PUNCT
asodahs-27	237	1	in	in	ADP
asodahs-27	237	2	this	this	DET
asodahs-27	237	3	work	work	NOUN
asodahs-27	237	4	,	,	PUNCT
asodahs-27	237	5	we	we	PRON
asodahs-27	237	6	discussed	discuss	VERB
asodahs-27	237	7	the	the	DET
asodahs-27	237	8	qualitative	qualitative	ADJ
asodahs-27	237	9	structure	structure	NOUN
asodahs-27	237	10	activity	activity	NOUN
asodahs-27	237	11	relationship	relationship	NOUN
asodahs-27	237	12	,	,	PUNCT
asodahs-27	237	13	a	a	DET
asodahs-27	237	14	computer	computer	NOUN
asodahs-27	237	15	-	-	PUNCT
asodahs-27	237	16	aided	aid	VERB
asodahs-27	237	17	drug	drug	NOUN
asodahs-27	237	18	discovery	discovery	NOUN
asodahs-27	237	19	process	process	NOUN
asodahs-27	237	20	with	with	ADP
asodahs-27	237	21	a	a	DET
asodahs-27	237	22	focus	focus	NOUN
asodahs-27	237	23	on	on	ADP
asodahs-27	237	24	anticancer	anticancer	NOUN
asodahs-27	237	25	drugs	drug	NOUN
asodahs-27	237	26	.	.	PUNCT
asodahs-27	238	1	keywords	keyword	NOUN
asodahs-27	238	2	:	:	PUNCT
asodahs-27	238	3	new	new	ADJ
asodahs-27	238	4	drug	drug	NOUN
asodahs-27	238	5	discovery	discovery	NOUN
asodahs-27	238	6	,	,	PUNCT
asodahs-27	238	7	computer	computer	NOUN
asodahs-27	238	8	-	-	PUNCT
asodahs-27	238	9	aided	aid	VERB
asodahs-27	238	10	drug	drug	NOUN
asodahs-27	238	11	discovery	discovery	NOUN
asodahs-27	238	12	,	,	PUNCT
asodahs-27	238	13	the	the	DET
asodahs-27	238	14	qualitative	qualitative	ADJ
asodahs-27	238	15	structure	structure	NOUN
asodahs-27	238	16	activity	activity	NOUN
asodahs-27	238	17	relationship	relationship	NOUN
asodahs-27	238	18	,	,	PUNCT
asodahs-27	238	19	anticancer	anticancer	NOUN
asodahs-27	238	20	introduction	introduction	NOUN
asodahs-27	238	21	up	up	ADP
asodahs-27	238	22	to	to	ADP
asodahs-27	238	23	now	now	ADV
asodahs-27	238	24	,	,	PUNCT
asodahs-27	238	25	cancer	cancer	NOUN
asodahs-27	238	26	remains	remain	VERB
asodahs-27	238	27	a	a	DET
asodahs-27	238	28	global	global	ADJ
asodahs-27	238	29	and	and	CCONJ
asodahs-27	238	30	serious	serious	ADJ
asodahs-27	238	31	public	public	ADJ
asodahs-27	238	32	health	health	NOUN
asodahs-27	238	33	challenge	challenge	NOUN
asodahs-27	238	34	.	.	PUNCT
asodahs-27	239	1	it	it	PRON
asodahs-27	239	2	is	be	AUX
asodahs-27	239	3	estimated	estimate	VERB
asodahs-27	239	4	that	that	SCONJ
asodahs-27	239	5	there	there	PRON
asodahs-27	239	6	are	be	VERB
asodahs-27	239	7	more	more	ADJ
asodahs-27	239	8	than	than	ADP
asodahs-27	239	9	200	200	NUM
asodahs-27	239	10	different	different	ADJ
asodahs-27	239	11	types	type	NOUN
asodahs-27	239	12	of	of	ADP
asodahs-27	239	13	cancer	cancer	NOUN
asodahs-27	239	14	,	,	PUNCT
asodahs-27	239	15	generally	generally	ADV
asodahs-27	239	16	named	name	VERB
asodahs-27	239	17	according	accord	VERB
asodahs-27	239	18	to	to	ADP
asodahs-27	239	19	the	the	DET
asodahs-27	239	20	tissue	tissue	NOUN
asodahs-27	239	21	where	where	SCONJ
asodahs-27	239	22	the	the	DET
asodahs-27	239	23	cancer	cancer	NOUN
asodahs-27	239	24	was	be	AUX
asodahs-27	239	25	recognized	recognize	VERB
asodahs-27	239	26	for	for	ADP
asodahs-27	239	27	the	the	DET
asodahs-27	239	28	first	first	ADJ
asodahs-27	239	29	time	time	NOUN
asodahs-27	239	30	.	.	PUNCT
asodahs-27	240	1	cancer	cancer	NOUN
asodahs-27	240	2	is	be	AUX
asodahs-27	240	3	considered	consider	VERB
asodahs-27	240	4	to	to	PART
asodahs-27	240	5	be	be	AUX
asodahs-27	240	6	one	one	NUM
asodahs-27	240	7	of	of	ADP
asodahs-27	240	8	the	the	DET
asodahs-27	240	9	significant	significant	ADJ
asodahs-27	240	10	causes	cause	NOUN
asodahs-27	240	11	for	for	ADP
asodahs-27	240	12	death	death	NOUN
asodahs-27	240	13	in	in	ADP
asodahs-27	240	14	the	the	DET
asodahs-27	240	15	21st	21st	ADJ
asodahs-27	240	16	century	century	NOUN
asodahs-27	240	17	and	and	CCONJ
asodahs-27	240	18	the	the	DET
asodahs-27	240	19	most	most	ADV
asodahs-27	240	20	critical	critical	ADJ
asodahs-27	240	21	obstacle	obstacle	NOUN
asodahs-27	240	22	for	for	ADP
asodahs-27	240	23	the	the	DET
asodahs-27	240	24	increase	increase	NOUN
asodahs-27	240	25	of	of	ADP
asodahs-27	240	26	global	global	ADJ
asodahs-27	240	27	life	life	NOUN
asodahs-27	240	28	expectancy	expectancy	NOUN
asodahs-27	240	29	.	.	PUNCT
asodahs-27	241	1	according	accord	VERB
asodahs-27	241	2	to	to	ADP
asodahs-27	241	3	an	an	DET
asodahs-27	241	4	analysis	analysis	NOUN
asodahs-27	241	5	by	by	ADP
asodahs-27	241	6	the	the	DET
asodahs-27	241	7	world	world	PROPN
asodahs-27	241	8	health	health	PROPN
asodahs-27	241	9	organization	organization	NOUN
asodahs-27	241	10	(	(	PUNCT
asodahs-27	241	11	who	who	PRON
asodahs-27	241	12	)	)	PUNCT
asodahs-27	241	13	in	in	ADP
asodahs-27	241	14	2015	2015	NUM
asodahs-27	241	15	,	,	PUNCT
asodahs-27	241	16	cancer	cancer	NOUN
asodahs-27	241	17	is	be	AUX
asodahs-27	241	18	the	the	DET
asodahs-27	241	19	second	second	ADJ
asodahs-27	241	20	leading	leading	ADJ
asodahs-27	241	21	cause	cause	NOUN
asodahs-27	241	22	of	of	ADP
asodahs-27	241	23	death	death	NOUN
asodahs-27	241	24	for	for	ADP
asodahs-27	241	25	patients	patient	NOUN
asodahs-27	241	26	younger	young	ADJ
asodahs-27	241	27	than	than	ADP
asodahs-27	241	28	70	70	NUM
asodahs-27	241	29	years	year	NOUN
asodahs-27	241	30	old	old	ADJ
asodahs-27	241	31	in	in	ADP
asodahs-27	241	32	91	91	NUM
asodahs-27	241	33	countries	country	NOUN
asodahs-27	241	34	and	and	CCONJ
asodahs-27	241	35	the	the	DET
asodahs-27	241	36	third	third	ADJ
asodahs-27	241	37	or	or	CCONJ
asodahs-27	241	38	fourth	fourth	ADJ
asodahs-27	241	39	leading	leading	ADJ
asodahs-27	241	40	cause	cause	NOUN
asodahs-27	241	41	of	of	ADP
asodahs-27	241	42	death	death	NOUN
asodahs-27	241	43	among	among	ADP
asodahs-27	241	44	22	22	NUM
asodahs-27	241	45	other	other	ADJ
asodahs-27	241	46	countries1	countries1	PROPN
asodahs-27	241	47	.	.	PUNCT
asodahs-27	242	1	moreover	moreover	ADV
asodahs-27	242	2	,	,	PUNCT
asodahs-27	242	3	a	a	DET
asodahs-27	242	4	global	global	ADJ
asodahs-27	242	5	increase	increase	NOUN
asodahs-27	242	6	of	of	ADP
asodahs-27	242	7	18.1	18.1	NUM
asodahs-27	242	8	million	million	NUM
asodahs-27	242	9	new	new	ADJ
asodahs-27	242	10	cancer	cancer	NOUN
asodahs-27	242	11	cases	case	NOUN
asodahs-27	242	12	and	and	CCONJ
asodahs-27	242	13	9.6	9.6	NUM
asodahs-27	242	14	million	million	NUM
asodahs-27	242	15	cancer	cancer	NOUN
asodahs-27	242	16	-	-	PUNCT
asodahs-27	242	17	related	relate	VERB
asodahs-27	242	18	deaths	death	NOUN
asodahs-27	242	19	have	have	AUX
asodahs-27	242	20	been	be	AUX
asodahs-27	242	21	reported	report	VERB
asodahs-27	242	22	in	in	ADP
asodahs-27	242	23	a	a	DET
asodahs-27	242	24	previous	previous	ADJ
asodahs-27	242	25	study2	study2	NOUN
asodahs-27	242	26	,	,	PUNCT
asodahs-27	242	27	especially	especially	ADV
asodahs-27	242	28	70	70	NUM
asodahs-27	242	29	%	%	NOUN
asodahs-27	242	30	of	of	ADP
asodahs-27	242	31	the	the	DET
asodahs-27	242	32	death	death	NOUN
asodahs-27	242	33	caused	cause	VERB
asodahs-27	242	34	by	by	ADP
asodahs-27	242	35	cancer	cancer	NOUN
asodahs-27	242	36	occur	occur	VERB
asodahs-27	242	37	in	in	ADP
asodahs-27	242	38	lowincome	lowincome	NOUN
asodahs-27	242	39	and	and	CCONJ
asodahs-27	242	40	middle	middle	ADJ
asodahs-27	242	41	-	-	PUNCT
asodahs-27	242	42	income	income	NOUN
asodahs-27	242	43	countries	country	NOUN
asodahs-27	242	44	.	.	PUNCT
asodahs-27	243	1	the	the	DET
asodahs-27	243	2	fast	fast	ADJ
asodahs-27	243	3	growth	growth	NOUN
asodahs-27	243	4	of	of	ADP
asodahs-27	243	5	the	the	DET
asodahs-27	243	6	cancer	cancer	NOUN
asodahs-27	243	7	incidence	incidence	NOUN
asodahs-27	243	8	and	and	CCONJ
asodahs-27	243	9	mortality	mortality	NOUN
asodahs-27	243	10	has	have	AUX
asodahs-27	243	11	turned	turn	VERB
asodahs-27	243	12	out	out	ADP
asodahs-27	243	13	to	to	PART
asodahs-27	243	14	be	be	AUX
asodahs-27	243	15	global	global	ADJ
asodahs-27	243	16	health	health	NOUN
asodahs-27	243	17	challenges	challenge	NOUN
asodahs-27	243	18	.	.	PUNCT
asodahs-27	244	1	how	how	SCONJ
asodahs-27	244	2	to	to	PART
asodahs-27	244	3	reduce	reduce	VERB
asodahs-27	244	4	the	the	DET
asodahs-27	244	5	cancer	cancer	NOUN
asodahs-27	244	6	-	-	PUNCT
asodahs-27	244	7	related	relate	VERB
asodahs-27	244	8	death	death	NOUN
asodahs-27	244	9	rate	rate	NOUN
asodahs-27	244	10	has	have	AUX
asodahs-27	244	11	attracted	attract	VERB
asodahs-27	244	12	significant	significant	ADJ
asodahs-27	244	13	attention	attention	NOUN
asodahs-27	244	14	from	from	ADP
asodahs-27	244	15	the	the	DET
asodahs-27	244	16	government	government	NOUN
asodahs-27	244	17	,	,	PUNCT
asodahs-27	244	18	society	society	NOUN
asodahs-27	244	19	,	,	PUNCT
asodahs-27	244	20	medical	medical	ADJ
asodahs-27	244	21	industry	industry	NOUN
asodahs-27	244	22	,	,	PUNCT
asodahs-27	244	23	as	as	ADV
asodahs-27	244	24	well	well	ADV
asodahs-27	244	25	as	as	ADP
asodahs-27	244	26	scientific	scientific	ADJ
asodahs-27	244	27	communities	community	NOUN
asodahs-27	244	28	,	,	PUNCT
asodahs-27	244	29	expecting	expect	VERB
asodahs-27	244	30	the	the	DET
asodahs-27	244	31	rapid	rapid	ADJ
asodahs-27	244	32	development	development	NOUN
asodahs-27	244	33	of	of	ADP
asodahs-27	244	34	effective	effective	ADJ
asodahs-27	244	35	and	and	CCONJ
asodahs-27	244	36	safe	safe	ADJ
asodahs-27	244	37	drugs	drug	NOUN
asodahs-27	244	38	for	for	ADP
asodahs-27	244	39	cancer	cancer	NOUN
asodahs-27	244	40	treatment	treatment	NOUN
asodahs-27	244	41	.	.	PUNCT
asodahs-27	245	1	despite	despite	SCONJ
asodahs-27	245	2	of	of	ADP
asodahs-27	245	3	the	the	DET
asodahs-27	245	4	impressive	impressive	ADJ
asodahs-27	245	5	progress	progress	NOUN
asodahs-27	245	6	in	in	ADP
asodahs-27	245	7	biotechnologies	biotechnology	NOUN
asodahs-27	245	8	and	and	CCONJ
asodahs-27	245	9	further	further	ADJ
asodahs-27	245	10	understandings	understanding	NOUN
asodahs-27	245	11	of	of	ADP
asodahs-27	245	12	the	the	DET
asodahs-27	245	13	disease	disease	NOUN
asodahs-27	245	14	biology	biology	NOUN
asodahs-27	245	15	,	,	PUNCT
asodahs-27	245	16	the	the	DET
asodahs-27	245	17	development	development	NOUN
asodahs-27	245	18	of	of	ADP
asodahs-27	245	19	new	new	ADJ
asodahs-27	245	20	,	,	PUNCT
asodahs-27	245	21	practical	practical	ADJ
asodahs-27	245	22	and	and	CCONJ
asodahs-27	245	23	innovative	innovative	ADJ
asodahs-27	245	24	small	small	ADJ
asodahs-27	245	25	molecule	molecule	NOUN
asodahs-27	245	26	drugs	drug	NOUN
asodahs-27	245	27	remains	remain	VERB
asodahs-27	245	28	an	an	DET
asodahs-27	245	29	arduous	arduous	ADJ
asodahs-27	245	30	,	,	PUNCT
asodahs-27	245	31	time	time	NOUN
asodahs-27	245	32	consuming	consuming	NOUN
asodahs-27	245	33	and	and	CCONJ
asodahs-27	245	34	expensive	expensive	ADJ
asodahs-27	245	35	project	project	NOUN
asodahs-27	245	36	,	,	PUNCT
asodahs-27	245	37	which	which	PRON
asodahs-27	245	38	requires	require	VERB
asodahs-27	245	39	collaborations	collaboration	NOUN
asodahs-27	245	40	from	from	ADP
asodahs-27	245	41	many	many	ADJ
asodahs-27	245	42	expertise	expertise	NOUN
asodahs-27	245	43	in	in	ADP
asodahs-27	245	44	multidisciplinary	multidisciplinary	ADJ
asodahs-27	245	45	fields	field	NOUN
asodahs-27	245	46	,	,	PUNCT
asodahs-27	245	47	including	include	VERB
asodahs-27	245	48	medicinal	medicinal	ADJ
asodahs-27	245	49	chemistry	chemistry	NOUN
asodahs-27	245	50	,	,	PUNCT
asodahs-27	245	51	computational	computational	ADJ
asodahs-27	245	52	chemistry	chemistry	NOUN
asodahs-27	245	53	,	,	PUNCT
asodahs-27	245	54	biology	biology	NOUN
asodahs-27	245	55	,	,	PUNCT
asodahs-27	245	56	drug	drug	NOUN
asodahs-27	245	57	metabolism	metabolism	NOUN
asodahs-27	245	58	,	,	PUNCT
asodahs-27	245	59	clinical	clinical	ADJ
asodahs-27	245	60	research	research	NOUN
asodahs-27	245	61	,	,	PUNCT
asodahs-27	245	62	etc	etc	X
asodahs-27	245	63	.	.	X
asodahs-27	246	1	furthermore	furthermore	ADV
asodahs-27	246	2	,	,	PUNCT
asodahs-27	246	3	it	it	PRON
asodahs-27	246	4	has	have	AUX
asodahs-27	246	5	been	be	AUX
asodahs-27	246	6	illustrated	illustrate	VERB
asodahs-27	246	7	that	that	SCONJ
asodahs-27	246	8	the	the	DET
asodahs-27	246	9	successful	successful	ADJ
asodahs-27	246	10	discovery	discovery	NOUN
asodahs-27	246	11	and	and	CCONJ
asodahs-27	246	12	development	development	NOUN
asodahs-27	246	13	of	of	ADP
asodahs-27	246	14	a	a	DET
asodahs-27	246	15	new	new	ADJ
asodahs-27	246	16	drug	drug	NOUN
asodahs-27	246	17	costs	cost	NOUN
asodahs-27	246	18	12	12	NUM
asodahs-27	246	19	years	year	NOUN
asodahs-27	246	20	,	,	PUNCT
asodahs-27	246	21	and	and	CCONJ
asodahs-27	246	22	expensive	expensive	ADJ
asodahs-27	246	23	investment3	investment3	NOUN
asodahs-27	246	24	.	.	PUNCT
asodahs-27	247	1	thus	thus	ADV
asodahs-27	247	2	,	,	PUNCT
asodahs-27	247	3	novel	novel	ADJ
asodahs-27	247	4	drug	drug	NOUN
asodahs-27	247	5	development	development	NOUN
asodahs-27	247	6	strategies	strategy	NOUN
asodahs-27	247	7	with	with	ADP
asodahs-27	247	8	a	a	DET
asodahs-27	247	9	reduced	reduced	ADJ
asodahs-27	247	10	cost	cost	NOUN
asodahs-27	247	11	of	of	ADP
asodahs-27	247	12	time	time	NOUN
asodahs-27	247	13	and	and	CCONJ
asodahs-27	247	14	money	money	NOUN
asodahs-27	247	15	,	,	PUNCT
asodahs-27	247	16	as	as	ADV
asodahs-27	247	17	well	well	ADV
asodahs-27	247	18	as	as	ADP
asodahs-27	247	19	an	an	DET
asodahs-27	247	20	enhanced	enhanced	ADJ
asodahs-27	247	21	efficiency	efficiency	NOUN
asodahs-27	247	22	are	be	AUX
asodahs-27	247	23	in	in	ADP
asodahs-27	247	24	high	high	ADJ
asodahs-27	247	25	demand	demand	NOUN
asodahs-27	247	26	,	,	PUNCT
asodahs-27	247	27	which	which	PRON
asodahs-27	247	28	would	would	AUX
asodahs-27	247	29	contribute	contribute	VERB
asodahs-27	247	30	to	to	ADP
asodahs-27	247	31	a	a	DET
asodahs-27	247	32	significant	significant	ADJ
asodahs-27	247	33	improvement	improvement	NOUN
asodahs-27	247	34	in	in	ADP
asodahs-27	247	35	global	global	ADJ
asodahs-27	247	36	health	health	NOUN
asodahs-27	247	37	and	and	CCONJ
asodahs-27	247	38	life	life	NOUN
asodahs-27	247	39	expectancy	expectancy	NOUN
asodahs-27	247	40	.	.	PUNCT
asodahs-27	248	1	since	since	SCONJ
asodahs-27	248	2	the	the	DET
asodahs-27	248	3	successful	successful	ADJ
asodahs-27	248	4	development	development	NOUN
asodahs-27	248	5	of	of	ADP
asodahs-27	248	6	hiv	hiv	PROPN
asodahs-27	248	7	protease	protease	NOUN
asodahs-27	248	8	inhibitor	inhibitor	NOUN
asodahs-27	248	9	viracept	viracept	VERB
asodahs-27	248	10	in	in	ADP
asodahs-27	248	11	the	the	DET
asodahs-27	248	12	usa	usa	PROPN
asodahs-27	248	13	in	in	ADP
asodahs-27	248	14	1997	1997	NUM
asodahs-27	248	15	,	,	PUNCT
asodahs-27	248	16	which	which	PRON
asodahs-27	248	17	was	be	AUX
asodahs-27	248	18	the	the	DET
asodahs-27	248	19	first	first	ADJ
asodahs-27	248	20	drug	drug	NOUN
asodahs-27	248	21	design	design	NOUN
asodahs-27	248	22	fully	fully	ADV
asodahs-27	248	23	driven	drive	VERB
asodahs-27	248	24	by	by	ADP
asodahs-27	248	25	its	its	PRON
asodahs-27	248	26	target	target	NOUN
asodahs-27	248	27	structure4	structure4	PROPN
asodahs-27	248	28	,	,	PUNCT
asodahs-27	248	29	computational	computational	ADJ
asodahs-27	248	30	methods	method	NOUN
asodahs-27	248	31	have	have	AUX
asodahs-27	248	32	served	serve	VERB
asodahs-27	248	33	as	as	ADP
asodahs-27	248	34	an	an	DET
asodahs-27	248	35	essential	essential	ADJ
asodahs-27	248	36	tool	tool	NOUN
asodahs-27	248	37	in	in	ADP
asodahs-27	248	38	drug	drug	NOUN
asodahs-27	248	39	discovery	discovery	NOUN
asodahs-27	248	40	projects	project	NOUN
asodahs-27	248	41	and	and	CCONJ
asodahs-27	248	42	have	have	AUX
asodahs-27	248	43	been	be	AUX
asodahs-27	248	44	a	a	DET
asodahs-27	248	45	cornerstone	cornerstone	NOUN
asodahs-27	248	46	for	for	ADP
asodahs-27	248	47	new	new	ADJ
asodahs-27	248	48	drug	drug	NOUN
asodahs-27	248	49	development	development	NOUN
asodahs-27	248	50	approaches	approach	NOUN
asodahs-27	248	51	.	.	PUNCT
asodahs-27	249	1	this	this	PRON
asodahs-27	249	2	makes	make	VERB
asodahs-27	249	3	the	the	DET
asodahs-27	249	4	drug	drug	NOUN
asodahs-27	249	5	developmental	developmental	ADJ
asodahs-27	249	6	process	process	NOUN
asodahs-27	249	7	faster	fast	ADV
asodahs-27	249	8	and	and	CCONJ
asodahs-27	249	9	cheaper	cheap	ADJ
asodahs-27	249	10	.	.	PUNCT
asodahs-27	250	1	recently	recently	ADV
asodahs-27	250	2	,	,	PUNCT
asodahs-27	250	3	the	the	DET
asodahs-27	250	4	fast	fast	ADJ
asodahs-27	250	5	growth	growth	NOUN
asodahs-27	250	6	in	in	ADP
asodahs-27	250	7	computational	computational	ADJ
asodahs-27	250	8	power	power	NOUN
asodahs-27	250	9	,	,	PUNCT
asodahs-27	250	10	including	include	VERB
asodahs-27	250	11	massively	massively	ADV
asodahs-27	250	12	parallel	parallel	ADJ
asodahs-27	250	13	computing	computing	NOUN
asodahs-27	250	14	on	on	ADP
asodahs-27	250	15	graphical	graphical	ADJ
asodahs-27	250	16	processing	processing	NOUN
asodahs-27	250	17	units	unit	NOUN
asodahs-27	250	18	(	(	PUNCT
asodahs-27	250	19	gpus	gpus	PROPN
asodahs-27	250	20	)	)	PUNCT
asodahs-27	250	21	,	,	PUNCT
asodahs-27	250	22	the	the	DET
asodahs-27	250	23	continuous	continuous	ADJ
asodahs-27	250	24	advances	advance	NOUN
asodahs-27	250	25	in	in	ADP
asodahs-27	250	26	artificial	artificial	ADJ
asodahs-27	250	27	intelligence	intelligence	NOUN
asodahs-27	250	28	(	(	PUNCT
asodahs-27	250	29	ai	ai	PROPN
asodahs-27	250	30	)	)	PUNCT
asodahs-27	250	31	tools5,6	tools5,6	PROPN
asodahs-27	250	32	,	,	PUNCT
asodahs-27	250	33	have	have	AUX
asodahs-27	250	34	translated	translate	VERB
asodahs-27	250	35	fundamental	fundamental	ADJ
asodahs-27	250	36	research	research	NOUN
asodahs-27	250	37	into	into	ADP
asodahs-27	250	38	practical	practical	ADJ
asodahs-27	250	39	applications7	applications7	NOUN
asodahs-27	250	40	in	in	ADP
asodahs-27	250	41	the	the	DET
asodahs-27	250	42	drug	drug	NOUN
asodahs-27	250	43	discovery	discovery	NOUN
asodahs-27	250	44	field	field	NOUN
asodahs-27	250	45	.	.	PUNCT
asodahs-27	251	1	this	this	PRON
asodahs-27	251	2	attracted	attract	VERB
asodahs-27	251	3	considerable	considerable	ADJ
asodahs-27	251	4	attention	attention	NOUN
asodahs-27	251	5	for	for	ADP
asodahs-27	251	6	their	their	PRON
asodahs-27	251	7	outstanding	outstanding	ADJ
asodahs-27	251	8	performance	performance	NOUN
asodahs-27	251	9	on	on	ADP
asodahs-27	251	10	providing	provide	VERB
asodahs-27	251	11	new	new	ADJ
asodahs-27	251	12	promising	promising	ADJ
asodahs-27	251	13	perspectives	perspective	NOUN
asodahs-27	251	14	and	and	CCONJ
asodahs-27	251	15	solutions	solution	NOUN
asodahs-27	251	16	to	to	PART
asodahs-27	251	17	overcome	overcome	VERB
asodahs-27	251	18	life	life	NOUN
asodahs-27	251	19	threatening	threaten	VERB
asodahs-27	251	20	diseases	disease	NOUN
asodahs-27	251	21	.	.	PUNCT
asodahs-27	252	1	in	in	ADP
asodahs-27	252	2	this	this	DET
asodahs-27	252	3	review	review	NOUN
asodahs-27	252	4	,	,	PUNCT
asodahs-27	252	5	we	we	PRON
asodahs-27	252	6	aim	aim	VERB
asodahs-27	252	7	at	at	ADP
asodahs-27	252	8	providing	provide	VERB
asodahs-27	252	9	an	an	DET
asodahs-27	252	10	overview	overview	NOUN
asodahs-27	252	11	of	of	ADP
asodahs-27	252	12	qsar	qsar	NOUN
asodahs-27	252	13	-	-	PUNCT
asodahs-27	252	14	method	method	NOUN
asodahs-27	252	15	and	and	CCONJ
asodahs-27	252	16	anti	anti	ADJ
asodahs-27	252	17	-	-	ADJ
asodahs-27	252	18	cancer	cancer	ADJ
asodahs-27	252	19	therapy	therapy	NOUN
asodahs-27	252	20	discovery	discovery	NOUN
asodahs-27	252	21	in	in	ADP
asodahs-27	252	22	particular	particular	ADJ
asodahs-27	252	23	.	.	PUNCT
asodahs-27	253	1	we	we	PRON
asodahs-27	253	2	reviewed	review	VERB
asodahs-27	253	3	some	some	PRON
asodahs-27	253	4	of	of	ADP
asodahs-27	253	5	the	the	DET
asodahs-27	253	6	most	most	ADV
asodahs-27	253	7	representative	representative	ADJ
asodahs-27	253	8	examples	example	NOUN
asodahs-27	253	9	and	and	CCONJ
asodahs-27	253	10	clarified	clarify	VERB
asodahs-27	253	11	fundamental	fundamental	ADJ
asodahs-27	253	12	principles	principle	NOUN
asodahs-27	253	13	by	by	ADP
asodahs-27	253	14	exploring	explore	VERB
asodahs-27	253	15	studies	study	NOUN
asodahs-27	253	16	on	on	ADP
asodahs-27	253	17	anticancer	anticancer	NOUN
asodahs-27	253	18	drug	drug	NOUN
asodahs-27	253	19	designs	design	NOUN
asodahs-27	253	20	with	with	ADP
asodahs-27	253	21	the	the	DET
asodahs-27	253	22	help	help	NOUN
asodahs-27	253	23	of	of	ADP
asodahs-27	253	24	qsar	qsar	NOUN
asodahs-27	253	25	methods	method	NOUN
asodahs-27	253	26	.	.	PUNCT
asodahs-27	254	1	anti	anti	ADJ
asodahs-27	254	2	-	-	ADJ
asodahs-27	254	3	cancer	cancer	ADJ
asodahs-27	254	4	drug	drug	NOUN
asodahs-27	254	5	target	target	NOUN
asodahs-27	254	6	prediction	prediction	NOUN
asodahs-27	254	7	human	human	NOUN
asodahs-27	254	8	contains	contain	VERB
asodahs-27	254	9	approximately	approximately	ADV
asodahs-27	254	10	30,000	30,000	NUM
asodahs-27	254	11	genes	gene	NOUN
asodahs-27	254	12	,	,	PUNCT
asodahs-27	254	13	among	among	ADP
asodahs-27	254	14	which	which	PRON
asodahs-27	254	15	around	around	ADP
asodahs-27	254	16	6,000	6,000	NUM
asodahs-27	254	17	to	to	PART
asodahs-27	254	18	8,000	8,000	NUM
asodahs-27	254	19	sites	site	NOUN
asodahs-27	254	20	are	be	AUX
asodahs-27	254	21	estimated	estimate	VERB
asodahs-27	254	22	as	as	ADP
asodahs-27	254	23	potential	potential	ADJ
asodahs-27	254	24	pharmacological	pharmacological	ADJ
asodahs-27	254	25	targets	target	NOUN
asodahs-27	254	26	.	.	PUNCT
asodahs-27	255	1	however	however	ADV
asodahs-27	255	2	,	,	PUNCT
asodahs-27	255	3	less	less	ADJ
asodahs-27	255	4	than	than	ADP
asodahs-27	255	5	400	400	NUM
asodahs-27	255	6	encoded	encode	VERB
asodahs-27	255	7	open	open	ADJ
asodahs-27	255	8	access	access	NOUN
asodahs-27	255	9	review	review	NOUN
asodahs-27	255	10	article	article	NOUN
asodahs-27	255	11	http://jddtonline.info/	http://jddtonline.info/	PROPN
asodahs-27	255	12	http://dx.doi.org/10.22270/ajdhs.v2i4.27	http://dx.doi.org/10.22270/ajdhs.v2i4.27	PROPN
asodahs-27	255	13	ahirwar	ahirwar	PROPN
asodahs-27	255	14	et	et	PROPN
asodahs-27	255	15	al	al	PROPN
asodahs-27	255	16	asian	asian	PROPN
asodahs-27	255	17	journal	journal	PROPN
asodahs-27	255	18	of	of	ADP
asodahs-27	255	19	dental	dental	ADJ
asodahs-27	255	20	and	and	CCONJ
asodahs-27	255	21	health	health	NOUN
asodahs-27	255	22	sciences	science	NOUN
asodahs-27	255	23	.	.	PUNCT
asodahs-27	255	24	2022	2022	NUM
asodahs-27	255	25	;	;	PUNCT
asodahs-27	255	26	2(4):59	2(4):59	NUM
asodahs-27	255	27	-	-	SYM
asodahs-27	255	28	63	63	NUM
asodahs-27	256	1	[	[	X
asodahs-27	256	2	60	60	NUM
asodahs-27	256	3	]	]	PUNCT
asodahs-27	256	4	ajdhs.com	ajdhs.com	X
asodahs-27	256	5	proteins	protein	NOUN
asodahs-27	256	6	have	have	AUX
asodahs-27	256	7	been	be	AUX
asodahs-27	256	8	proved	prove	VERB
asodahs-27	256	9	to	to	PART
asodahs-27	256	10	be	be	AUX
asodahs-27	256	11	effective	effective	ADJ
asodahs-27	256	12	for	for	ADP
asodahs-27	256	13	drug	drug	NOUN
asodahs-27	256	14	development	development	NOUN
asodahs-27	256	15	until	until	ADP
asodahs-27	256	16	now8,9	now8,9	PROPN
asodahs-27	256	17	.	.	PUNCT
asodahs-27	256	18	cancer	cancer	NOUN
asodahs-27	256	19	,	,	PUNCT
asodahs-27	256	20	compared	compare	VERB
asodahs-27	256	21	to	to	ADP
asodahs-27	256	22	many	many	ADJ
asodahs-27	256	23	other	other	ADJ
asodahs-27	256	24	human	human	ADJ
asodahs-27	256	25	diseases	disease	NOUN
asodahs-27	256	26	,	,	PUNCT
asodahs-27	256	27	now	now	ADV
asodahs-27	256	28	has	have	VERB
asodahs-27	256	29	a	a	DET
asodahs-27	256	30	plethora	plethora	NOUN
asodahs-27	256	31	of	of	ADP
asodahs-27	256	32	potential	potential	ADJ
asodahs-27	256	33	molecular	molecular	ADJ
asodahs-27	256	34	targets	target	NOUN
asodahs-27	256	35	for	for	ADP
asodahs-27	256	36	therapeutic	therapeutic	ADJ
asodahs-27	256	37	development10	development10	NOUN
asodahs-27	256	38	.	.	PUNCT
asodahs-27	257	1	traditional	traditional	ADJ
asodahs-27	257	2	drug	drug	NOUN
asodahs-27	257	3	discovery	discovery	PROPN
asodahs-27	257	4	mainly	mainly	ADV
asodahs-27	257	5	follows	follow	VERB
asodahs-27	257	6	the	the	DET
asodahs-27	257	7	paradigm	paradigm	NOUN
asodahs-27	257	8	of	of	ADP
asodahs-27	257	9	"	"	PUNCT
asodahs-27	257	10	one	one	NUM
asodahs-27	257	11	molecule	molecule	NOUN
asodahs-27	257	12	one	one	NUM
asodahs-27	257	13	target	target	NOUN
asodahs-27	257	14	one	one	NUM
asodahs-27	257	15	disease	disease	NOUN
asodahs-27	257	16	"	"	PUNCT
asodahs-27	257	17	,	,	PUNCT
asodahs-27	257	18	without	without	ADP
asodahs-27	257	19	considering	consider	VERB
asodahs-27	257	20	the	the	DET
asodahs-27	257	21	interactions	interaction	NOUN
asodahs-27	257	22	between	between	ADP
asodahs-27	257	23	drugs	drug	NOUN
asodahs-27	257	24	and	and	CCONJ
asodahs-27	257	25	proteins	protein	NOUN
asodahs-27	257	26	.	.	PUNCT
asodahs-27	258	1	however	however	ADV
asodahs-27	258	2	,	,	PUNCT
asodahs-27	258	3	an	an	DET
asodahs-27	258	4	important	important	ADJ
asodahs-27	258	5	fact	fact	NOUN
asodahs-27	258	6	that	that	SCONJ
asodahs-27	258	7	many	many	ADJ
asodahs-27	258	8	complex	complex	ADJ
asodahs-27	258	9	diseases	disease	NOUN
asodahs-27	258	10	are	be	AUX
asodahs-27	258	11	relevant	relevant	ADJ
asodahs-27	258	12	to	to	ADP
asodahs-27	258	13	a	a	DET
asodahs-27	258	14	variety	variety	NOUN
asodahs-27	258	15	of	of	ADP
asodahs-27	258	16	target	target	NOUN
asodahs-27	258	17	proteins11	proteins11	NOUN
asodahs-27	258	18	-	-	PUNCT
asodahs-27	258	19	13	13	NUM
asodahs-27	258	20	has	have	AUX
asodahs-27	258	21	been	be	AUX
asodahs-27	258	22	overlooked	overlook	VERB
asodahs-27	258	23	.	.	PUNCT
asodahs-27	259	1	furthermore	furthermore	ADV
asodahs-27	259	2	,	,	PUNCT
asodahs-27	259	3	unexpected	unexpected	ADJ
asodahs-27	259	4	drug	drug	NOUN
asodahs-27	259	5	functions	function	NOUN
asodahs-27	259	6	derived	derive	VERB
asodahs-27	259	7	from	from	ADP
asodahs-27	259	8	off	off	ADP
asodahs-27	259	9	-	-	PUNCT
asodahs-27	259	10	targets	target	NOUN
asodahs-27	259	11	are	be	AUX
asodahs-27	259	12	accidental	accidental	ADJ
asodahs-27	259	13	and	and	CCONJ
asodahs-27	259	14	uncontrollable	uncontrollable	ADJ
asodahs-27	259	15	activities	activity	NOUN
asodahs-27	259	16	because	because	SCONJ
asodahs-27	259	17	of	of	ADP
asodahs-27	259	18	the	the	DET
asodahs-27	259	19	‘	'	PUNCT
asodahs-27	259	20	poly	poly	ADJ
asodahs-27	259	21	pharmacological	pharmacological	NOUN
asodahs-27	259	22	’	'	PUNCT
asodahs-27	259	23	properties	property	NOUN
asodahs-27	259	24	of	of	ADP
asodahs-27	259	25	certain	certain	ADJ
asodahs-27	259	26	drugs	drug	NOUN
asodahs-27	259	27	,	,	PUNCT
asodahs-27	259	28	which	which	PRON
asodahs-27	259	29	might	might	AUX
asodahs-27	259	30	result	result	VERB
asodahs-27	259	31	in	in	ADP
asodahs-27	259	32	undesirable	undesirable	ADJ
asodahs-27	259	33	side	side	NOUN
asodahs-27	259	34	effects	effect	NOUN
asodahs-27	259	35	.	.	PUNCT
asodahs-27	260	1	those	those	PRON
asodahs-27	260	2	are	be	AUX
asodahs-27	260	3	particularly	particularly	ADV
asodahs-27	260	4	pronounced	pronounce	VERB
asodahs-27	260	5	for	for	ADP
asodahs-27	260	6	cancer	cancer	NOUN
asodahs-27	260	7	drugs	drug	NOUN
asodahs-27	260	8	.	.	PUNCT
asodahs-27	261	1	on	on	ADP
asodahs-27	261	2	the	the	DET
asodahs-27	261	3	other	other	ADJ
asodahs-27	261	4	hand	hand	NOUN
asodahs-27	261	5	,	,	PUNCT
asodahs-27	261	6	there	there	PRON
asodahs-27	261	7	are	be	VERB
asodahs-27	261	8	some	some	DET
asodahs-27	261	9	positive	positive	ADJ
asodahs-27	261	10	examples	example	NOUN
asodahs-27	261	11	that	that	PRON
asodahs-27	261	12	benefit	benefit	VERB
asodahs-27	261	13	from	from	ADP
asodahs-27	261	14	the	the	DET
asodahs-27	261	15	different	different	ADJ
asodahs-27	261	16	pathways	pathway	NOUN
asodahs-27	261	17	targeted	target	VERB
asodahs-27	261	18	by	by	ADP
asodahs-27	261	19	one	one	NUM
asodahs-27	261	20	given	give	VERB
asodahs-27	261	21	molecule	molecule	NOUN
asodahs-27	261	22	.	.	PUNCT
asodahs-27	262	1	for	for	ADP
asodahs-27	262	2	example	example	NOUN
asodahs-27	262	3	,	,	PUNCT
asodahs-27	262	4	sildenafil	sildenafil	X
asodahs-27	262	5	(	(	PUNCT
asodahs-27	262	6	viagra	viagra	NOUN
asodahs-27	262	7	)	)	PUNCT
asodahs-27	262	8	was	be	AUX
asodahs-27	262	9	developed	develop	VERB
asodahs-27	262	10	to	to	PART
asodahs-27	262	11	treat	treat	VERB
asodahs-27	262	12	angina	angina	ADJ
asodahs-27	262	13	,	,	PUNCT
asodahs-27	262	14	but	but	CCONJ
asodahs-27	262	15	now	now	ADV
asodahs-27	262	16	it	it	PRON
asodahs-27	262	17	is	be	AUX
asodahs-27	262	18	used	use	VERB
asodahs-27	262	19	for	for	ADP
asodahs-27	262	20	erectile	erectile	ADJ
asodahs-27	262	21	dysfunction	dysfunction	NOUN
asodahs-27	262	22	therapy14	therapy14	NOUN
asodahs-27	262	23	.	.	PUNCT
asodahs-27	263	1	there	there	PRON
asodahs-27	263	2	are	be	VERB
asodahs-27	263	3	several	several	ADJ
asodahs-27	263	4	drugs	drug	NOUN
asodahs-27	263	5	,	,	PUNCT
asodahs-27	263	6	including	include	VERB
asodahs-27	263	7	anticancer	anticancer	NOUN
asodahs-27	263	8	drugs	drug	NOUN
asodahs-27	263	9	,	,	PUNCT
asodahs-27	263	10	whose	whose	DET
asodahs-27	263	11	corresponding	corresponding	ADJ
asodahs-27	263	12	target	target	NOUN
asodahs-27	263	13	proteins	protein	NOUN
asodahs-27	263	14	(	(	PUNCT
asodahs-27	263	15	both	both	CCONJ
asodahs-27	263	16	primary	primary	ADJ
asodahs-27	263	17	and	and	CCONJ
asodahs-27	263	18	nontarget	nontarget	NOUN
asodahs-27	263	19	)	)	PUNCT
asodahs-27	263	20	remain	remain	VERB
asodahs-27	263	21	yet	yet	ADV
asodahs-27	263	22	unidentified	unidentified	ADJ
asodahs-27	263	23	or	or	CCONJ
asodahs-27	263	24	unknown15	unknown15	NOUN
asodahs-27	263	25	.	.	PUNCT
asodahs-27	264	1	furthermore	furthermore	ADV
asodahs-27	264	2	,	,	PUNCT
asodahs-27	264	3	some	some	DET
asodahs-27	264	4	attractive	attractive	ADJ
asodahs-27	264	5	and	and	CCONJ
asodahs-27	264	6	potentially	potentially	ADV
asodahs-27	264	7	effective	effective	ADJ
asodahs-27	264	8	cancer	cancer	NOUN
asodahs-27	264	9	targets	target	NOUN
asodahs-27	264	10	remain	remain	VERB
asodahs-27	264	11	outside	outside	ADP
asodahs-27	264	12	of	of	ADP
asodahs-27	264	13	the	the	DET
asodahs-27	264	14	scope	scope	NOUN
asodahs-27	264	15	of	of	ADP
asodahs-27	264	16	pharmacological	pharmacological	ADJ
asodahs-27	264	17	regulation	regulation	NOUN
asodahs-27	264	18	.	.	PUNCT
asodahs-27	265	1	some	some	PRON
asodahs-27	265	2	of	of	ADP
asodahs-27	265	3	these	these	DET
asodahs-27	265	4	targets	target	NOUN
asodahs-27	265	5	such	such	ADJ
asodahs-27	265	6	as	as	ADP
asodahs-27	265	7	phosphatases	phosphatase	NOUN
asodahs-27	265	8	,	,	PUNCT
asodahs-27	265	9	transcription	transcription	NOUN
asodahs-27	265	10	factors	factor	NOUN
asodahs-27	265	11	,	,	PUNCT
asodahs-27	265	12	and	and	CCONJ
asodahs-27	265	13	ras	ras	PROPN
asodahs-27	265	14	family	family	NOUN
asodahs-27	265	15	members	member	NOUN
asodahs-27	265	16	have	have	AUX
asodahs-27	265	17	been	be	AUX
asodahs-27	265	18	described	describe	VERB
asodahs-27	265	19	as	as	ADP
asodahs-27	265	20	undruggable	undruggable	ADJ
asodahs-27	265	21	,	,	PUNCT
asodahs-27	265	22	as	as	SCONJ
asodahs-27	265	23	they	they	PRON
asodahs-27	265	24	lack	lack	VERB
asodahs-27	265	25	effective	effective	ADJ
asodahs-27	265	26	enzymatic	enzymatic	ADJ
asodahs-27	265	27	active	active	ADJ
asodahs-27	265	28	sites10	sites10	NOUN
asodahs-27	265	29	.	.	PUNCT
asodahs-27	266	1	to	to	PART
asodahs-27	266	2	make	make	VERB
asodahs-27	266	3	the	the	DET
asodahs-27	266	4	full	full	ADJ
asodahs-27	266	5	use	use	NOUN
asodahs-27	266	6	of	of	ADP
asodahs-27	266	7	known	know	VERB
asodahs-27	266	8	drugs	drug	NOUN
asodahs-27	266	9	to	to	PART
asodahs-27	266	10	treat	treat	VERB
asodahs-27	266	11	new	new	ADJ
asodahs-27	266	12	indications	indication	NOUN
asodahs-27	266	13	,	,	PUNCT
asodahs-27	266	14	the	the	DET
asodahs-27	266	15	characterization	characterization	NOUN
asodahs-27	266	16	of	of	ADP
asodahs-27	266	17	all	all	DET
asodahs-27	266	18	potential	potential	ADJ
asodahs-27	266	19	new	new	ADJ
asodahs-27	266	20	ligand	ligand	NOUN
asodahs-27	266	21	binding	bind	VERB
asodahs-27	266	22	sites	site	NOUN
asodahs-27	266	23	has	have	AUX
asodahs-27	266	24	been	be	AUX
asodahs-27	266	25	illustrated	illustrate	VERB
asodahs-27	266	26	as	as	ADP
asodahs-27	266	27	a	a	DET
asodahs-27	266	28	key	key	ADJ
asodahs-27	266	29	point	point	NOUN
asodahs-27	266	30	in	in	ADP
asodahs-27	266	31	drug	drug	NOUN
asodahs-27	266	32	repositioning	repositioning	NOUN
asodahs-27	266	33	and	and	CCONJ
asodahs-27	266	34	repurposing	repurposing	NOUN
asodahs-27	266	35	.	.	PUNCT
asodahs-27	267	1	therefore	therefore	ADV
asodahs-27	267	2	,	,	PUNCT
asodahs-27	267	3	new	new	ADJ
asodahs-27	267	4	and	and	CCONJ
asodahs-27	267	5	highly	highly	ADV
asodahs-27	267	6	qualitative	qualitative	ADJ
asodahs-27	267	7	bioinformatic	bioinformatic	ADJ
asodahs-27	267	8	target	target	NOUN
asodahs-27	267	9	prediction	prediction	NOUN
asodahs-27	267	10	methods	method	NOUN
asodahs-27	267	11	are	be	AUX
asodahs-27	267	12	required	require	VERB
asodahs-27	267	13	for	for	ADP
asodahs-27	267	14	the	the	DET
asodahs-27	267	15	accurate	accurate	ADJ
asodahs-27	267	16	prediction	prediction	NOUN
asodahs-27	267	17	of	of	ADP
asodahs-27	267	18	drug	drug	NOUN
asodahs-27	267	19	targets	target	NOUN
asodahs-27	267	20	.	.	PUNCT
asodahs-27	268	1	up	up	ADP
asodahs-27	268	2	to	to	ADP
asodahs-27	268	3	now	now	ADV
asodahs-27	268	4	,	,	PUNCT
asodahs-27	268	5	a	a	DET
asodahs-27	268	6	wide	wide	ADJ
asodahs-27	268	7	range	range	NOUN
asodahs-27	268	8	of	of	ADP
asodahs-27	268	9	drug	drug	NOUN
asodahs-27	268	10	target	target	NOUN
asodahs-27	268	11	interactive	interactive	ADJ
asodahs-27	268	12	web	web	NOUN
asodahs-27	268	13	servers	server	NOUN
asodahs-27	268	14	has	have	AUX
asodahs-27	268	15	been	be	AUX
asodahs-27	268	16	established	establish	VERB
asodahs-27	268	17	,	,	PUNCT
asodahs-27	268	18	providing	provide	VERB
asodahs-27	268	19	a	a	DET
asodahs-27	268	20	series	series	NOUN
asodahs-27	268	21	of	of	ADP
asodahs-27	268	22	drug	drug	NOUN
asodahs-27	268	23	-	-	PUNCT
asodahs-27	268	24	target	target	NOUN
asodahs-27	268	25	databases	database	NOUN
asodahs-27	268	26	and	and	CCONJ
asodahs-27	268	27	prediction	prediction	NOUN
asodahs-27	268	28	tools	tool	NOUN
asodahs-27	268	29	.	.	PUNCT
asodahs-27	269	1	moreover	moreover	ADV
asodahs-27	269	2	,	,	PUNCT
asodahs-27	269	3	various	various	ADJ
asodahs-27	269	4	computational	computational	ADJ
asodahs-27	269	5	approaches	approach	NOUN
asodahs-27	269	6	have	have	AUX
asodahs-27	269	7	been	be	AUX
asodahs-27	269	8	used	use	VERB
asodahs-27	269	9	to	to	PART
asodahs-27	269	10	study	study	VERB
asodahs-27	269	11	potential	potential	ADJ
asodahs-27	269	12	interactions	interaction	NOUN
asodahs-27	269	13	between	between	ADP
asodahs-27	269	14	proteins	protein	NOUN
asodahs-27	269	15	and	and	CCONJ
asodahs-27	269	16	drugs	drug	NOUN
asodahs-27	269	17	.	.	PUNCT
asodahs-27	270	1	in	in	ADP
asodahs-27	270	2	particular	particular	ADJ
asodahs-27	270	3	,	,	PUNCT
asodahs-27	270	4	network	network	NOUN
asodahs-27	270	5	-	-	PUNCT
asodahs-27	270	6	based	base	VERB
asodahs-27	270	7	models	model	NOUN
asodahs-27	270	8	and	and	CCONJ
asodahs-27	270	9	ml	ml	NOUN
asodahs-27	270	10	-	-	PUNCT
asodahs-27	270	11	based	base	VERB
asodahs-27	270	12	models	model	NOUN
asodahs-27	270	13	have	have	AUX
asodahs-27	270	14	emerged	emerge	VERB
asodahs-27	270	15	as	as	ADP
asodahs-27	270	16	important	important	ADJ
asodahs-27	270	17	tools	tool	NOUN
asodahs-27	270	18	.	.	PUNCT
asodahs-27	271	1	a	a	DET
asodahs-27	271	2	review	review	NOUN
asodahs-27	271	3	by	by	ADP
asodahs-27	271	4	chen	chen	PROPN
asodahs-27	271	5	et	et	PROPN
asodahs-27	271	6	al	al	PROPN
asodahs-27	271	7	.	.	PROPN
asodahs-27	271	8	summarizes	summarize	VERB
asodahs-27	271	9	several	several	ADJ
asodahs-27	271	10	available	available	ADJ
asodahs-27	271	11	computational	computational	ADJ
asodahs-27	271	12	models	model	NOUN
asodahs-27	271	13	for	for	ADP
asodahs-27	271	14	this	this	DET
asodahs-27	271	15	application13	application13	NOUN
asodahs-27	271	16	.	.	PUNCT
asodahs-27	272	1	interestingly	interestingly	ADV
asodahs-27	272	2	,	,	PUNCT
asodahs-27	272	3	a	a	DET
asodahs-27	272	4	method	method	NOUN
asodahs-27	272	5	proposed	propose	VERB
asodahs-27	272	6	by	by	ADP
asodahs-27	272	7	campillos	campillos	PROPN
asodahs-27	272	8	et	et	PROPN
asodahs-27	272	9	al	al	PROPN
asodahs-27	272	10	.	.	PROPN
asodahs-27	273	1	that	that	PRON
asodahs-27	273	2	uses	use	VERB
asodahs-27	273	3	the	the	DET
asodahs-27	273	4	similarity	similarity	NOUN
asodahs-27	273	5	of	of	ADP
asodahs-27	273	6	drug	drug	NOUN
asodahs-27	273	7	side	side	NOUN
asodahs-27	273	8	effects	effect	NOUN
asodahs-27	273	9	to	to	PART
asodahs-27	273	10	determine	determine	VERB
asodahs-27	273	11	whether	whether	SCONJ
asodahs-27	273	12	multiple	multiple	ADJ
asodahs-27	273	13	drugs	drug	NOUN
asodahs-27	273	14	could	could	AUX
asodahs-27	273	15	interact	interact	VERB
asodahs-27	273	16	with	with	ADP
asodahs-27	273	17	the	the	DET
asodahs-27	273	18	same	same	ADJ
asodahs-27	273	19	target	target	NOUN
asodahs-27	273	20	proteins	protein	NOUN
asodahs-27	273	21	attracted	attract	VERB
asodahs-27	273	22	our	our	PRON
asodahs-27	273	23	attention16	attention16	NOUN
asodahs-27	273	24	.	.	PUNCT
asodahs-27	274	1	based	base	VERB
asodahs-27	274	2	on	on	ADP
asodahs-27	274	3	this	this	DET
asodahs-27	274	4	research	research	NOUN
asodahs-27	274	5	,	,	PUNCT
asodahs-27	274	6	takarabe	takarabe	INTJ
asodahs-27	274	7	et	et	PROPN
asodahs-27	274	8	al	al	PROPN
asodahs-27	274	9	.	.	PROPN
asodahs-27	274	10	took	take	VERB
asodahs-27	274	11	advantage	advantage	NOUN
asodahs-27	274	12	of	of	ADP
asodahs-27	274	13	the	the	DET
asodahs-27	274	14	us	us	PROPN
asodahs-27	274	15	fda	fda	PROPN
asodahs-27	274	16	’s	’s	PART
asodahs-27	274	17	adverse	adverse	ADJ
asodahs-27	274	18	event	event	NOUN
asodahs-27	274	19	reporting	reporting	NOUN
asodahs-27	274	20	system	system	NOUN
asodahs-27	274	21	(	(	PUNCT
asodahs-27	274	22	aers	aer	NOUN
asodahs-27	274	23	)	)	PUNCT
asodahs-27	274	24	to	to	PART
asodahs-27	274	25	define	define	VERB
asodahs-27	274	26	the	the	DET
asodahs-27	274	27	pharmacological	pharmacological	ADJ
asodahs-27	274	28	similarity	similarity	NOUN
asodahs-27	274	29	of	of	ADP
asodahs-27	274	30	all	all	DET
asodahs-27	274	31	potential	potential	ADJ
asodahs-27	274	32	medicines	medicine	NOUN
asodahs-27	274	33	and	and	CCONJ
asodahs-27	274	34	developed	develop	VERB
asodahs-27	274	35	a	a	DET
asodahs-27	274	36	novel	novel	ADJ
asodahs-27	274	37	system	system	NOUN
asodahs-27	274	38	to	to	PART
asodahs-27	274	39	predict	predict	VERB
asodahs-27	274	40	large	large	ADJ
asodahs-27	274	41	-	-	PUNCT
asodahs-27	274	42	scale	scale	NOUN
asodahs-27	274	43	interactions	interaction	NOUN
asodahs-27	274	44	between	between	ADP
asodahs-27	274	45	unknown	unknown	ADJ
asodahs-27	274	46	drug	drug	NOUN
asodahs-27	274	47	targets15	targets15	PROPN
asodahs-27	274	48	.	.	PUNCT
asodahs-27	275	1	notably	notably	ADV
asodahs-27	275	2	,	,	PUNCT
asodahs-27	275	3	aers	aer	NOUN
asodahs-27	275	4	was	be	AUX
asodahs-27	275	5	employed	employ	VERB
asodahs-27	275	6	to	to	PART
asodahs-27	275	7	predict	predict	VERB
asodahs-27	275	8	interactions	interaction	NOUN
asodahs-27	275	9	between	between	ADP
asodahs-27	275	10	drugs	drug	NOUN
asodahs-27	275	11	and	and	CCONJ
asodahs-27	275	12	targets	target	NOUN
asodahs-27	275	13	for	for	ADP
asodahs-27	275	14	the	the	DET
asodahs-27	275	15	first	first	ADJ
asodahs-27	275	16	time	time	NOUN
asodahs-27	275	17	.	.	PUNCT
asodahs-27	276	1	in	in	ADP
asodahs-27	276	2	2010	2010	NUM
asodahs-27	276	3	,	,	PUNCT
asodahs-27	276	4	klipp	klipp	PROPN
asodahs-27	276	5	et	et	PROPN
asodahs-27	276	6	al	al	PROPN
asodahs-27	276	7	.	.	PROPN
asodahs-27	276	8	summarized	summarize	VERB
asodahs-27	276	9	several	several	ADJ
asodahs-27	276	10	available	available	ADJ
asodahs-27	276	11	computational	computational	ADJ
asodahs-27	276	12	models	model	NOUN
asodahs-27	276	13	for	for	ADP
asodahs-27	276	14	network	network	NOUN
asodahs-27	276	15	-	-	PUNCT
asodahs-27	276	16	based	base	VERB
asodahs-27	276	17	drug	drug	NOUN
asodahs-27	276	18	-	-	PUNCT
asodahs-27	276	19	target	target	NOUN
asodahs-27	276	20	prediction17	prediction17	NOUN
asodahs-27	276	21	.	.	PUNCT
asodahs-27	277	1	moreover	moreover	ADV
asodahs-27	277	2	,	,	PUNCT
asodahs-27	277	3	various	various	ADJ
asodahs-27	277	4	biological	biological	ADJ
asodahs-27	277	5	data	datum	NOUN
asodahs-27	277	6	settings	setting	NOUN
asodahs-27	277	7	,	,	PUNCT
asodahs-27	277	8	including	include	VERB
asodahs-27	277	9	structures	structure	NOUN
asodahs-27	277	10	of	of	ADP
asodahs-27	277	11	bioactive	bioactive	ADJ
asodahs-27	277	12	compounds	compound	NOUN
asodahs-27	277	13	,	,	PUNCT
asodahs-27	277	14	sequences	sequence	NOUN
asodahs-27	277	15	of	of	ADP
asodahs-27	277	16	target	target	NOUN
asodahs-27	277	17	proteins	protein	NOUN
asodahs-27	277	18	,	,	PUNCT
asodahs-27	277	19	and	and	CCONJ
asodahs-27	277	20	information	information	NOUN
asodahs-27	277	21	of	of	ADP
asodahs-27	277	22	ligand	ligand	NOUN
asodahs-27	277	23	-	-	PUNCT
asodahs-27	277	24	target	target	NOUN
asodahs-27	277	25	interactions	interaction	NOUN
asodahs-27	277	26	,	,	PUNCT
asodahs-27	277	27	have	have	AUX
asodahs-27	277	28	been	be	AUX
asodahs-27	277	29	combined	combine	VERB
asodahs-27	277	30	.	.	PUNCT
asodahs-27	278	1	a	a	DET
asodahs-27	278	2	series	series	NOUN
asodahs-27	278	3	of	of	ADP
asodahs-27	278	4	machine	machine	NOUN
asodahs-27	278	5	learning	learning	NOUN
asodahs-27	278	6	-	-	PUNCT
asodahs-27	278	7	based	base	VERB
asodahs-27	278	8	approaches	approach	NOUN
asodahs-27	278	9	have	have	AUX
asodahs-27	278	10	been	be	AUX
asodahs-27	278	11	demonstrated	demonstrate	VERB
asodahs-27	278	12	as	as	ADP
asodahs-27	278	13	efficient	efficient	ADJ
asodahs-27	278	14	tools	tool	NOUN
asodahs-27	278	15	in	in	ADP
asodahs-27	278	16	detecting	detect	VERB
asodahs-27	278	17	relationships	relationship	NOUN
asodahs-27	278	18	among	among	ADP
asodahs-27	278	19	drug	drug	NOUN
asodahs-27	278	20	structures	structure	NOUN
asodahs-27	278	21	and	and	CCONJ
asodahs-27	278	22	corresponding	correspond	VERB
asodahs-27	278	23	target	target	NOUN
asodahs-27	278	24	proteins	protein	NOUN
asodahs-27	278	25	from	from	ADP
asodahs-27	278	26	a	a	DET
asodahs-27	278	27	large	large	ADJ
asodahs-27	278	28	amount	amount	NOUN
asodahs-27	278	29	of	of	ADP
asodahs-27	278	30	data	datum	NOUN
asodahs-27	278	31	,	,	PUNCT
asodahs-27	278	32	such	such	ADJ
asodahs-27	278	33	as	as	ADP
asodahs-27	278	34	supervised	supervised	ADJ
asodahs-27	278	35	learning	learning	NOUN
asodahs-27	278	36	method18	method18	NOUN
asodahs-27	278	37	,	,	PUNCT
asodahs-27	278	38	bipartite	bipartite	PROPN
asodahs-27	278	39	graph	graph	NOUN
asodahs-27	278	40	learning	learn	VERB
asodahs-27	278	41	method19	method19	NOUN
asodahs-27	278	42	,	,	PUNCT
asodahs-27	278	43	bipartite	bipartite	PROPN
asodahs-27	278	44	local	local	ADJ
asodahs-27	278	45	model20and	model20and	NOUN
asodahs-27	278	46	so	so	ADV
asodahs-27	278	47	on	on	ADV
asodahs-27	278	48	.	.	PUNCT
asodahs-27	279	1	a	a	DET
asodahs-27	279	2	recent	recent	ADJ
asodahs-27	279	3	review	review	NOUN
asodahs-27	279	4	by	by	ADP
asodahs-27	279	5	mayr	mayr	PROPN
asodahs-27	279	6	et	et	PROPN
asodahs-27	279	7	al	al	PROPN
asodahs-27	279	8	.	.	PROPN
asodahs-27	279	9	compared	compare	VERB
asodahs-27	279	10	the	the	DET
asodahs-27	279	11	predictive	predictive	ADJ
asodahs-27	279	12	performance	performance	NOUN
asodahs-27	279	13	of	of	ADP
asodahs-27	279	14	deep	deep	ADJ
asodahs-27	279	15	learning	learning	NOUN
asodahs-27	279	16	with	with	ADP
asodahs-27	279	17	other	other	ADJ
asodahs-27	279	18	prediction	prediction	NOUN
asodahs-27	279	19	approaches	approach	NOUN
asodahs-27	279	20	for	for	ADP
asodahs-27	279	21	multiple	multiple	ADJ
asodahs-27	279	22	drug	drug	NOUN
asodahs-27	279	23	targets	target	NOUN
asodahs-27	279	24	in	in	ADP
asodahs-27	279	25	the	the	DET
asodahs-27	279	26	comparative	comparative	ADJ
asodahs-27	279	27	studies	study	NOUN
asodahs-27	279	28	of	of	ADP
asodahs-27	279	29	composite	composite	ADJ
asodahs-27	279	30	target	target	NOUN
asodahs-27	279	31	prediction	prediction	NOUN
asodahs-27	279	32	methods	method	NOUN
asodahs-27	279	33	.	.	PUNCT
asodahs-27	280	1	as	as	ADP
asodahs-27	280	2	a	a	DET
asodahs-27	280	3	result	result	NOUN
asodahs-27	280	4	,	,	PUNCT
asodahs-27	280	5	feed	feed	NOUN
asodahs-27	280	6	-	-	PUNCT
asodahs-27	280	7	forward	forward	NOUN
asodahs-27	280	8	neural	neural	ADJ
asodahs-27	280	9	networks	network	NOUN
asodahs-27	280	10	were	be	AUX
asodahs-27	280	11	identified	identify	VERB
asodahs-27	280	12	with	with	ADP
asodahs-27	280	13	better	well	ADJ
asodahs-27	280	14	performance	performance	NOUN
asodahs-27	280	15	in	in	ADP
asodahs-27	280	16	drug	drug	NOUN
asodahs-27	280	17	target	target	NOUN
asodahs-27	280	18	prediction	prediction	NOUN
asodahs-27	280	19	than	than	ADP
asodahs-27	280	20	other	other	ADJ
asodahs-27	280	21	methods21	methods21	NOUN
asodahs-27	280	22	.	.	PUNCT
asodahs-27	281	1	as	as	ADP
asodahs-27	281	2	above	above	ADV
asodahs-27	281	3	,	,	PUNCT
asodahs-27	281	4	since	since	SCONJ
asodahs-27	281	5	a	a	DET
asodahs-27	281	6	large	large	ADJ
asodahs-27	281	7	number	number	NOUN
asodahs-27	281	8	of	of	ADP
asodahs-27	281	9	compounds	compound	NOUN
asodahs-27	281	10	and	and	CCONJ
asodahs-27	281	11	vigorous	vigorous	ADJ
asodahs-27	281	12	efforts	effort	NOUN
asodahs-27	281	13	are	be	AUX
asodahs-27	281	14	abandoned	abandon	VERB
asodahs-27	281	15	and	and	CCONJ
asodahs-27	281	16	wasted	waste	VERB
asodahs-27	281	17	due	due	ADP
asodahs-27	281	18	to	to	ADP
asodahs-27	281	19	the	the	DET
asodahs-27	281	20	off	off	ADJ
asodahs-27	281	21	-	-	PUNCT
asodahs-27	281	22	target	target	NOUN
asodahs-27	281	23	effects	effect	NOUN
asodahs-27	281	24	during	during	ADP
asodahs-27	281	25	the	the	DET
asodahs-27	281	26	classical	classical	ADJ
asodahs-27	281	27	drug	drug	NOUN
asodahs-27	281	28	development	development	NOUN
asodahs-27	281	29	procedure	procedure	NOUN
asodahs-27	281	30	,	,	PUNCT
asodahs-27	281	31	a	a	DET
asodahs-27	281	32	greatly	greatly	ADV
asodahs-27	281	33	enhanced	enhance	VERB
asodahs-27	281	34	development	development	NOUN
asodahs-27	281	35	of	of	ADP
asodahs-27	281	36	target	target	NOUN
asodahs-27	281	37	prediction	prediction	NOUN
asodahs-27	281	38	in	in	ADP
asodahs-27	281	39	new	new	ADJ
asodahs-27	281	40	drug	drug	NOUN
asodahs-27	281	41	exploration	exploration	NOUN
asodahs-27	281	42	exhibited	exhibit	VERB
asodahs-27	281	43	attractive	attractive	ADJ
asodahs-27	281	44	advantages	advantage	NOUN
asodahs-27	281	45	and	and	CCONJ
asodahs-27	281	46	further	further	ADJ
asodahs-27	281	47	expansion	expansion	NOUN
asodahs-27	281	48	in	in	ADP
asodahs-27	281	49	this	this	DET
asodahs-27	281	50	area	area	NOUN
asodahs-27	281	51	are	be	AUX
asodahs-27	281	52	still	still	ADV
asodahs-27	281	53	highly	highly	ADV
asodahs-27	281	54	desirable	desirable	ADJ
asodahs-27	281	55	.	.	PUNCT
asodahs-27	282	1	quantitative	quantitative	ADJ
asodahs-27	282	2	structure	structure	NOUN
asodahs-27	282	3	activity	activity	NOUN
asodahs-27	282	4	relationship	relationship	NOUN
asodahs-27	282	5	qsar	qsar	NOUN
asodahs-27	282	6	(	(	PUNCT
asodahs-27	282	7	quantitative	quantitative	ADJ
asodahs-27	282	8	structure	structure	NOUN
asodahs-27	282	9	activity	activity	NOUN
asodahs-27	282	10	relationship	relationship	NOUN
asodahs-27	282	11	)	)	PUNCT
asodahs-27	282	12	is	be	AUX
asodahs-27	282	13	a	a	DET
asodahs-27	282	14	ligand	ligand	NOUN
asodahs-27	282	15	-	-	PUNCT
asodahs-27	282	16	based	base	VERB
asodahs-27	282	17	approach	approach	NOUN
asodahs-27	282	18	that	that	PRON
asodahs-27	282	19	relies	rely	VERB
asodahs-27	282	20	on	on	ADP
asodahs-27	282	21	analyzing	analyze	VERB
asodahs-27	282	22	the	the	DET
asodahs-27	282	23	biological	biological	ADJ
asodahs-27	282	24	activities	activity	NOUN
asodahs-27	282	25	of	of	ADP
asodahs-27	282	26	drugs	drug	NOUN
asodahs-27	282	27	using	use	VERB
asodahs-27	282	28	various	various	ADJ
asodahs-27	282	29	molecular	molecular	ADJ
asodahs-27	282	30	descriptors	descriptor	NOUN
asodahs-27	282	31	(	(	PUNCT
asodahs-27	282	32	mds	mds	NOUN
asodahs-27	282	33	)	)	PUNCT
asodahs-27	282	34	or	or	CCONJ
asodahs-27	282	35	fingerprints	fingerprint	NOUN
asodahs-27	282	36	(	(	PUNCT
asodahs-27	282	37	fps	fps	PROPN
asodahs-27	282	38	)	)	PUNCT
asodahs-27	282	39	.	.	PUNCT
asodahs-27	283	1	these	these	DET
asodahs-27	283	2	models	model	NOUN
asodahs-27	283	3	mathematically	mathematically	ADV
asodahs-27	283	4	describe	describe	VERB
asodahs-27	283	5	how	how	SCONJ
asodahs-27	283	6	the	the	DET
asodahs-27	283	7	activities	activity	NOUN
asodahs-27	283	8	response	response	VERB
asodahs-27	283	9	to	to	ADP
asodahs-27	283	10	the	the	DET
asodahs-27	283	11	targets	target	NOUN
asodahs-27	283	12	according	accord	VERB
asodahs-27	283	13	to	to	ADP
asodahs-27	283	14	the	the	DET
asodahs-27	283	15	ligand	ligand	NOUN
asodahs-27	283	16	's	's	PART
asodahs-27	283	17	structural	structural	ADJ
asodahs-27	283	18	characteristics	characteristic	NOUN
asodahs-27	283	19	.	.	PUNCT
asodahs-27	284	1	qsar	qsar	PROPN
asodahs-27	284	2	was	be	AUX
asodahs-27	284	3	obtained	obtain	VERB
asodahs-27	284	4	by	by	ADP
asodahs-27	284	5	calculating	calculate	VERB
asodahs-27	284	6	the	the	DET
asodahs-27	284	7	correlations	correlation	NOUN
asodahs-27	284	8	between	between	ADP
asodahs-27	284	9	the	the	DET
asodahs-27	284	10	properties	property	NOUN
asodahs-27	284	11	of	of	ADP
asodahs-27	284	12	the	the	DET
asodahs-27	284	13	ligand	ligand	ADJ
asodahs-27	284	14	binding	bind	VERB
asodahs-27	284	15	agent	agent	NOUN
asodahs-27	284	16	and	and	CCONJ
asodahs-27	284	17	the	the	DET
asodahs-27	284	18	biological	biological	ADJ
asodahs-27	284	19	activity	activity	NOUN
asodahs-27	284	20	measured	measure	VERB
asodahs-27	284	21	by	by	ADP
asodahs-27	284	22	experiments	experiment	NOUN
asodahs-27	284	23	.	.	PUNCT
asodahs-27	285	1	different	different	ADJ
asodahs-27	285	2	ml	ml	NOUN
asodahs-27	285	3	and	and	CCONJ
asodahs-27	285	4	deep	deep	ADJ
asodahs-27	285	5	learning	learning	NOUN
asodahs-27	285	6	(	(	PUNCT
asodahs-27	285	7	dl	dl	NOUN
asodahs-27	285	8	)	)	PUNCT
asodahs-27	285	9	approaches	approach	NOUN
asodahs-27	285	10	have	have	AUX
asodahs-27	285	11	also	also	ADV
asodahs-27	285	12	been	be	AUX
asodahs-27	285	13	applied	apply	VERB
asodahs-27	285	14	to	to	PART
asodahs-27	285	15	develop	develop	VERB
asodahs-27	285	16	qsar	qsar	PROPN
asodahs-27	285	17	models22	models22	NOUN
asodahs-27	285	18	:	:	PUNCT
asodahs-27	285	19	including	include	VERB
asodahs-27	285	20	support	support	NOUN
asodahs-27	285	21	vector	vector	NOUN
asodahs-27	285	22	machine	machine	NOUN
asodahs-27	285	23	(	(	PUNCT
asodahs-27	285	24	svm	svm	PROPN
asodahs-27	285	25	)	)	PUNCT
asodahs-27	285	26	,	,	PUNCT
asodahs-27	285	27	random	random	ADJ
asodahs-27	285	28	forest	forest	NOUN
asodahs-27	285	29	(	(	PUNCT
asodahs-27	285	30	rf	rf	NOUN
asodahs-27	285	31	)	)	PUNCT
asodahs-27	285	32	,	,	PUNCT
asodahs-27	285	33	polynomial	polynomial	ADJ
asodahs-27	285	34	regression	regression	NOUN
asodahs-27	285	35	(	(	PUNCT
asodahs-27	285	36	pr	pr	NOUN
asodahs-27	285	37	)	)	PUNCT
asodahs-27	285	38	,	,	PUNCT
asodahs-27	285	39	multi	multi	PROPN
asodahs-27	285	40	linear	linear	PROPN
asodahs-27	285	41	regression	regression	NOUN
asodahs-27	285	42	(	(	PUNCT
asodahs-27	285	43	mlr	mlr	NOUN
asodahs-27	285	44	)	)	PUNCT
asodahs-27	285	45	,	,	PUNCT
asodahs-27	285	46	artificial	artificial	ADJ
asodahs-27	285	47	neural	neural	ADJ
asodahs-27	285	48	network	network	NOUN
asodahs-27	285	49	(	(	PUNCT
asodahs-27	285	50	ann	ann	PROPN
asodahs-27	285	51	)	)	PUNCT
asodahs-27	285	52	.	.	PUNCT
asodahs-27	286	1	unlike	unlike	ADP
asodahs-27	286	2	the	the	DET
asodahs-27	286	3	pharmacophore	pharmacophore	NOUN
asodahs-27	286	4	models	model	NOUN
asodahs-27	286	5	,	,	PUNCT
asodahs-27	286	6	qsar	qsar	NOUN
asodahs-27	286	7	models	model	NOUN
asodahs-27	286	8	can	can	AUX
asodahs-27	286	9	measure	measure	VERB
asodahs-27	286	10	biological	biological	ADJ
asodahs-27	286	11	activities	activity	NOUN
asodahs-27	286	12	quantitatively	quantitatively	ADV
asodahs-27	286	13	and	and	CCONJ
asodahs-27	286	14	can	can	AUX
asodahs-27	286	15	even	even	ADV
asodahs-27	286	16	find	find	VERB
asodahs-27	286	17	positive	positive	ADJ
asodahs-27	286	18	or	or	CCONJ
asodahs-27	286	19	negative	negative	ADJ
asodahs-27	286	20	effects	effect	NOUN
asodahs-27	286	21	according	accord	VERB
asodahs-27	286	22	to	to	ADP
asodahs-27	286	23	certain	certain	ADJ
asodahs-27	286	24	characteristics	characteristic	NOUN
asodahs-27	286	25	of	of	ADP
asodahs-27	286	26	the	the	DET
asodahs-27	286	27	molecule	molecule	NOUN
asodahs-27	286	28	on	on	ADP
asodahs-27	286	29	its	its	PRON
asodahs-27	286	30	activity	activity	NOUN
asodahs-27	286	31	.	.	PUNCT
asodahs-27	287	1	qsar	qsar	PROPN
asodahs-27	287	2	has	have	AUX
asodahs-27	287	3	been	be	AUX
asodahs-27	287	4	applied	apply	VERB
asodahs-27	287	5	to	to	ADP
asodahs-27	287	6	many	many	ADJ
asodahs-27	287	7	other	other	ADJ
asodahs-27	287	8	molecular	molecular	ADJ
asodahs-27	287	9	design	design	NOUN
asodahs-27	287	10	purposes	purpose	NOUN
asodahs-27	287	11	,	,	PUNCT
asodahs-27	287	12	such	such	ADJ
asodahs-27	287	13	as	as	ADP
asodahs-27	287	14	predicting	predict	VERB
asodahs-27	287	15	the	the	DET
asodahs-27	287	16	new	new	ADJ
asodahs-27	287	17	molecule	molecule	NOUN
asodahs-27	287	18	analog	analog	NOUN
asodahs-27	287	19	activity	activity	NOUN
asodahs-27	287	20	,	,	PUNCT
asodahs-27	287	21	optimizing	optimize	VERB
asodahs-27	287	22	lead	lead	NOUN
asodahs-27	287	23	,	,	PUNCT
asodahs-27	287	24	and	and	CCONJ
asodahs-27	287	25	predicting	predict	VERB
asodahs-27	287	26	new	new	ADJ
asodahs-27	287	27	structural	structural	ADJ
asodahs-27	287	28	leads	lead	NOUN
asodahs-27	287	29	in	in	ADP
asodahs-27	287	30	drug	drug	NOUN
asodahs-27	287	31	discovery	discovery	NOUN
asodahs-27	287	32	.	.	PUNCT
asodahs-27	288	1	in	in	ADP
asodahs-27	288	2	the	the	DET
asodahs-27	288	3	classical	classical	ADJ
asodahs-27	288	4	2d	2d	NOUN
asodahs-27	288	5	-	-	PUNCT
asodahs-27	288	6	qsar	qsar	NOUN
asodahs-27	288	7	approaches	approach	NOUN
asodahs-27	288	8	,	,	PUNCT
asodahs-27	288	9	the	the	DET
asodahs-27	288	10	biological	biological	ADJ
asodahs-27	288	11	activity	activity	NOUN
asodahs-27	288	12	is	be	AUX
asodahs-27	288	13	related	relate	VERB
asodahs-27	288	14	to	to	ADP
asodahs-27	288	15	physical	physical	ADJ
asodahs-27	288	16	and	and	CCONJ
asodahs-27	288	17	chemical	chemical	NOUN
asodahs-27	288	18	features	feature	NOUN
asodahs-27	288	19	consisting	consist	VERB
asodahs-27	288	20	of	of	ADP
asodahs-27	288	21	steric	steric	ADJ
asodahs-27	288	22	,	,	PUNCT
asodahs-27	288	23	electronic	electronic	ADJ
asodahs-27	288	24	,	,	PUNCT
asodahs-27	288	25	and	and	CCONJ
asodahs-27	288	26	hydrophobic	hydrophobic	NOUN
asodahs-27	288	27	characters	character	NOUN
asodahs-27	288	28	of	of	ADP
asodahs-27	288	29	drugs	drug	NOUN
asodahs-27	288	30	,	,	PUNCT
asodahs-27	288	31	and	and	CCONJ
asodahs-27	288	32	the	the	DET
asodahs-27	288	33	relationships	relationship	NOUN
asodahs-27	288	34	are	be	AUX
asodahs-27	288	35	represented	represent	VERB
asodahs-27	288	36	as	as	ADP
asodahs-27	288	37	mathematical	mathematical	ADJ
asodahs-27	288	38	equations23	equations23	NOUN
asodahs-27	288	39	.	.	PUNCT
asodahs-27	289	1	more	more	ADV
asodahs-27	289	2	advanced	advanced	ADJ
asodahs-27	289	3	3d	3d	NUM
asodahs-27	289	4	-	-	PUNCT
asodahs-27	289	5	qsar	qsar	NOUN
asodahs-27	289	6	approaches	approach	NOUN
asodahs-27	289	7	,	,	PUNCT
asodahs-27	289	8	such	such	ADJ
asodahs-27	289	9	as	as	ADP
asodahs-27	289	10	comparative	comparative	ADJ
asodahs-27	289	11	molecular	molecular	ADJ
asodahs-27	289	12	field	field	NOUN
asodahs-27	289	13	analysis24	analysis24	NOUN
asodahs-27	289	14	and	and	CCONJ
asodahs-27	289	15	molecular	molecular	ADJ
asodahs-27	289	16	similarity	similarity	NOUN
asodahs-27	289	17	indexes	index	NOUN
asodahs-27	289	18	in	in	ADP
asodahs-27	289	19	a	a	DET
asodahs-27	289	20	comparative	comparative	ADJ
asodahs-27	289	21	analysis25	analysis25	NOUN
asodahs-27	289	22	,	,	PUNCT
asodahs-27	289	23	are	be	AUX
asodahs-27	289	24	based	base	VERB
asodahs-27	289	25	on	on	ADP
asodahs-27	289	26	the	the	DET
asodahs-27	289	27	force	force	NOUN
asodahs-27	289	28	field	field	NOUN
asodahs-27	289	29	calculations	calculation	NOUN
asodahs-27	289	30	.	.	PUNCT
asodahs-27	290	1	the	the	DET
asodahs-27	290	2	structural	structural	ADJ
asodahs-27	290	3	information	information	NOUN
asodahs-27	290	4	of	of	ADP
asodahs-27	290	5	molecules	molecule	NOUN
asodahs-27	290	6	is	be	AUX
asodahs-27	290	7	needed	need	VERB
asodahs-27	290	8	,	,	PUNCT
asodahs-27	290	9	and	and	CCONJ
asodahs-27	290	10	developed	develop	VERB
asodahs-27	290	11	models	model	NOUN
asodahs-27	290	12	are	be	AUX
asodahs-27	290	13	represented	represent	VERB
asodahs-27	290	14	in	in	ADP
asodahs-27	290	15	3d	3d	NUM
asodahs-27	290	16	contour	contour	NOUN
asodahs-27	290	17	maps	map	NOUN
asodahs-27	290	18	facilitating	facilitate	VERB
asodahs-27	290	19	the	the	DET
asodahs-27	290	20	visualization	visualization	NOUN
asodahs-27	290	21	and	and	CCONJ
asodahs-27	290	22	interpretation	interpretation	NOUN
asodahs-27	290	23	successful	successful	ADJ
asodahs-27	290	24	stories	story	NOUN
asodahs-27	290	25	of	of	ADP
asodahs-27	290	26	computational	computational	ADJ
asodahs-27	290	27	drug	drug	NOUN
asodahs-27	290	28	discovery	discovery	NOUN
asodahs-27	290	29	qsar	qsar	NOUN
asodahs-27	290	30	methods	method	NOUN
asodahs-27	290	31	have	have	AUX
asodahs-27	290	32	proved	prove	VERB
asodahs-27	290	33	to	to	PART
asodahs-27	290	34	play	play	VERB
asodahs-27	290	35	an	an	DET
asodahs-27	290	36	essential	essential	ADJ
asodahs-27	290	37	role	role	NOUN
asodahs-27	290	38	in	in	ADP
asodahs-27	290	39	modern	modern	ADJ
asodahs-27	290	40	drug	drug	NOUN
asodahs-27	290	41	discovery	discovery	NOUN
asodahs-27	290	42	.	.	PUNCT
asodahs-27	291	1	since	since	SCONJ
asodahs-27	291	2	computational	computational	ADJ
asodahs-27	291	3	methods	method	NOUN
asodahs-27	291	4	could	could	AUX
asodahs-27	291	5	cover	cover	VERB
asodahs-27	291	6	almost	almost	ADV
asodahs-27	291	7	all	all	PRON
asodahs-27	291	8	stages	stage	NOUN
asodahs-27	291	9	of	of	ADP
asodahs-27	291	10	the	the	DET
asodahs-27	291	11	drug	drug	NOUN
asodahs-27	291	12	discovery	discovery	NOUN
asodahs-27	291	13	pipeline	pipeline	NOUN
asodahs-27	291	14	,	,	PUNCT
asodahs-27	291	15	the	the	DET
asodahs-27	291	16	applications	application	NOUN
asodahs-27	291	17	of	of	ADP
asodahs-27	291	18	qsar	qsar	NOUN
asodahs-27	291	19	methods	method	NOUN
asodahs-27	291	20	in	in	ADP
asodahs-27	291	21	anticancer	anticancer	NOUN
asodahs-27	291	22	drug	drug	NOUN
asodahs-27	291	23	discoveries	discovery	NOUN
asodahs-27	291	24	have	have	AUX
asodahs-27	291	25	shown	show	VERB
asodahs-27	291	26	great	great	ADJ
asodahs-27	291	27	advantages	advantage	NOUN
asodahs-27	291	28	in	in	ADP
asodahs-27	291	29	terms	term	NOUN
asodahs-27	291	30	of	of	ADP
asodahs-27	291	31	the	the	DET
asodahs-27	291	32	required	required	ADJ
asodahs-27	291	33	investment	investment	NOUN
asodahs-27	291	34	,	,	PUNCT
asodahs-27	291	35	resources	resource	NOUN
asodahs-27	291	36	,	,	PUNCT
asodahs-27	291	37	and	and	CCONJ
asodahs-27	291	38	time	time	NOUN
asodahs-27	291	39	.	.	PUNCT
asodahs-27	292	1	more	more	ADV
asodahs-27	292	2	recently	recently	ADV
asodahs-27	292	3	,	,	PUNCT
asodahs-27	292	4	qsar	qsar	NOUN
asodahs-27	292	5	methods	method	NOUN
asodahs-27	292	6	have	have	AUX
asodahs-27	292	7	become	become	VERB
asodahs-27	292	8	a	a	DET
asodahs-27	292	9	potent	potent	ADJ
asodahs-27	292	10	and	and	CCONJ
asodahs-27	292	11	powerful	powerful	ADJ
asodahs-27	292	12	tool	tool	NOUN
asodahs-27	292	13	in	in	ADP
asodahs-27	292	14	several	several	ADJ
asodahs-27	292	15	successful	successful	ADJ
asodahs-27	292	16	cases	case	NOUN
asodahs-27	292	17	of	of	ADP
asodahs-27	292	18	anticancer	anticancer	NOUN
asodahs-27	292	19	drug	drug	NOUN
asodahs-27	292	20	development	development	NOUN
asodahs-27	292	21	.	.	PUNCT
asodahs-27	293	1	herein	herein	NOUN
asodahs-27	293	2	,	,	PUNCT
asodahs-27	293	3	we	we	PRON
asodahs-27	293	4	list	list	VERB
asodahs-27	293	5	several	several	ADJ
asodahs-27	293	6	successful	successful	ADJ
asodahs-27	293	7	applications	application	NOUN
asodahs-27	293	8	of	of	ADP
asodahs-27	293	9	qsar	qsar	NOUN
asodahs-27	293	10	methods	method	NOUN
asodahs-27	293	11	for	for	ADP
asodahs-27	293	12	small	small	ADJ
asodahs-27	293	13	molecule	molecule	NOUN
asodahs-27	293	14	drugs	drug	NOUN
asodahs-27	293	15	,	,	PUNCT
asodahs-27	293	16	which	which	PRON
asodahs-27	293	17	have	have	AUX
asodahs-27	293	18	been	be	AUX
asodahs-27	293	19	applied	apply	VERB
asodahs-27	293	20	to	to	ADP
asodahs-27	293	21	cancer	cancer	NOUN
asodahs-27	293	22	treatment	treatment	NOUN
asodahs-27	293	23	or	or	CCONJ
asodahs-27	293	24	are	be	AUX
asodahs-27	293	25	at	at	ADP
asodahs-27	293	26	later	later	ADJ
asodahs-27	293	27	stages	stage	NOUN
asodahs-27	293	28	in	in	ADP
asodahs-27	293	29	the	the	DET
asodahs-27	293	30	clinical	clinical	ADJ
asodahs-27	293	31	trial	trial	NOUN
asodahs-27	293	32	.	.	PUNCT
asodahs-27	294	1	in	in	ADP
asodahs-27	294	2	a	a	DET
asodahs-27	294	3	study	study	NOUN
asodahs-27	294	4	of	of	ADP
asodahs-27	294	5	alomori	alomori	PROPN
asodahs-27	294	6	et	et	PROPN
asodahs-27	294	7	al	al	PROPN
asodahs-27	294	8	.	.	PROPN
asodahs-27	294	9	,	,	PUNCT
asodahs-27	294	10	four	four	NUM
asodahs-27	294	11	oxidovanadium(iv	oxidovanadium(iv	ADJ
asodahs-27	294	12	)	)	PUNCT
asodahs-27	294	13	complexes	complex	NOUN
asodahs-27	294	14	have	have	AUX
asodahs-27	294	15	been	be	AUX
asodahs-27	294	16	synthesized	synthesize	VERB
asodahs-27	294	17	and	and	CCONJ
asodahs-27	294	18	characterized	characterize	VERB
asodahs-27	294	19	by	by	ADP
asodahs-27	294	20	several	several	ADJ
asodahs-27	294	21	spectroscopic	spectroscopic	ADJ
asodahs-27	294	22	methods	method	NOUN
asodahs-27	294	23	.	.	PUNCT
asodahs-27	295	1	the	the	DET
asodahs-27	295	2	ir	ir	PROPN
asodahs-27	295	3	spectra	spectra	PROPN
asodahs-27	295	4	suggested	suggest	VERB
asodahs-27	295	5	that	that	SCONJ
asodahs-27	295	6	the	the	DET
asodahs-27	295	7	ligands	ligand	NOUN
asodahs-27	295	8	have	have	VERB
asodahs-27	295	9	bidentate	bidentate	NOUN
asodahs-27	295	10	coordination	coordination	NOUN
asodahs-27	295	11	mode	mode	NOUN
asodahs-27	295	12	to	to	ADP
asodahs-27	295	13	the	the	DET
asodahs-27	295	14	vanadium	vanadium	NOUN
asodahs-27	295	15	ion	ion	NOUN
asodahs-27	295	16	.	.	PUNCT
asodahs-27	296	1	in	in	ADP
asodahs-27	296	2	addition	addition	NOUN
asodahs-27	296	3	,	,	PUNCT
asodahs-27	296	4	the	the	DET
asodahs-27	296	5	molar	molar	ADJ
asodahs-27	296	6	conductance	conductance	NOUN
asodahs-27	296	7	,	,	PUNCT
asodahs-27	296	8	epr	epr	PROPN
asodahs-27	296	9	,	,	PUNCT
asodahs-27	296	10	magnetic	magnetic	ADJ
asodahs-27	296	11	moment	moment	NOUN
asodahs-27	296	12	values	value	NOUN
asodahs-27	296	13	,	,	PUNCT
asodahs-27	296	14	and	and	CCONJ
asodahs-27	296	15	electronic	electronic	ADJ
asodahs-27	296	16	data	datum	NOUN
asodahs-27	296	17	support	support	VERB
asodahs-27	296	18	a	a	DET
asodahs-27	296	19	square	square	ADJ
asodahs-27	296	20	pyramidal	pyramidal	ADJ
asodahs-27	296	21	structure	structure	NOUN
asodahs-27	296	22	for	for	ADP
asodahs-27	296	23	all	all	DET
asodahs-27	296	24	complexes	complex	NOUN
asodahs-27	296	25	.	.	PUNCT
asodahs-27	297	1	computational	computational	ADJ
asodahs-27	297	2	studies	study	NOUN
asodahs-27	297	3	were	be	AUX
asodahs-27	297	4	applied	apply	VERB
asodahs-27	297	5	to	to	PART
asodahs-27	297	6	demonstrate	demonstrate	VERB
asodahs-27	297	7	the	the	DET
asodahs-27	297	8	optimization	optimization	NOUN
asodahs-27	297	9	geometry	geometry	NOUN
asodahs-27	297	10	and	and	CCONJ
asodahs-27	297	11	essential	essential	ADJ
asodahs-27	297	12	quantum	quantum	ADJ
asodahs-27	297	13	parameters	parameter	NOUN
asodahs-27	297	14	and	and	CCONJ
asodahs-27	297	15	confirm	confirm	VERB
asodahs-27	297	16	their	their	PRON
asodahs-27	297	17	biological	biological	ADJ
asodahs-27	297	18	efficiency	efficiency	NOUN
asodahs-27	297	19	.	.	PUNCT
asodahs-27	298	1	the	the	DET
asodahs-27	298	2	metal	metal	NOUN
asodahs-27	298	3	complexes	complex	NOUN
asodahs-27	298	4	showed	show	VERB
asodahs-27	298	5	a	a	DET
asodahs-27	298	6	square	square	ADJ
asodahs-27	298	7	-	-	PUNCT
asodahs-27	298	8	pyramidal	pyramidal	NOUN
asodahs-27	298	9	geometry	geometry	NOUN
asodahs-27	298	10	arrangement	arrangement	NOUN
asodahs-27	298	11	around	around	ADP
asodahs-27	298	12	the	the	DET
asodahs-27	298	13	metal	metal	NOUN
asodahs-27	298	14	ion	ion	NOUN
asodahs-27	298	15	which	which	PRON
asodahs-27	298	16	was	be	AUX
asodahs-27	298	17	agreeable	agreeable	ADJ
asodahs-27	298	18	with	with	ADP
asodahs-27	298	19	experimental	experimental	ADJ
asodahs-27	298	20	results	result	NOUN
asodahs-27	298	21	.	.	PUNCT
asodahs-27	299	1	the	the	DET
asodahs-27	299	2	form	form	NOUN
asodahs-27	299	3	coordination	coordination	NOUN
asodahs-27	299	4	bonds	bond	NOUN
asodahs-27	299	5	length	length	NOUN
asodahs-27	299	6	presented	present	VERB
asodahs-27	299	7	strength	strength	NOUN
asodahs-27	299	8	bonded	bond	VERB
asodahs-27	299	9	between	between	ADP
asodahs-27	299	10	oxidovanadium(iv	oxidovanadium(iv	PROPN
asodahs-27	299	11	)	)	PUNCT
asodahs-27	299	12	and	and	CCONJ
asodahs-27	299	13	the	the	DET
asodahs-27	299	14	investigated	investigate	VERB
asodahs-27	299	15	ligand	ligand	NOUN
asodahs-27	299	16	to	to	PART
asodahs-27	299	17	form	form	VERB
asodahs-27	299	18	stable	stable	ADJ
asodahs-27	299	19	complexes	complex	NOUN
asodahs-27	299	20	.	.	PUNCT
asodahs-27	300	1	the	the	DET
asodahs-27	300	2	bioactivity	bioactivity	NOUN
asodahs-27	300	3	study	study	NOUN
asodahs-27	300	4	was	be	AUX
asodahs-27	300	5	varied	varied	ADJ
asodahs-27	300	6	and	and	CCONJ
asodahs-27	300	7	involved	involve	VERB
asodahs-27	300	8	dna	dna	NOUN
asodahs-27	300	9	-	-	PUNCT
asodahs-27	300	10	binding	bind	VERB
asodahs-27	300	11	,	,	PUNCT
asodahs-27	300	12	molecular	molecular	ADJ
asodahs-27	300	13	docking	docking	NOUN
asodahs-27	300	14	,	,	PUNCT
asodahs-27	300	15	qsar	qsar	NOUN
asodahs-27	300	16	,	,	PUNCT
asodahs-27	300	17	and	and	CCONJ
asodahs-27	300	18	cytotoxicity	cytotoxicity	NOUN
asodahs-27	300	19	analyses	analysis	NOUN
asodahs-27	300	20	.	.	PUNCT
asodahs-27	301	1	dna	dna	PROPN
asodahs-27	301	2	binding	bind	VERB
asodahs-27	301	3	results	result	NOUN
asodahs-27	301	4	revealed	reveal	VERB
asodahs-27	301	5	two	two	NUM
asodahs-27	301	6	behaviors	behavior	NOUN
asodahs-27	301	7	for	for	ADP
asodahs-27	301	8	the	the	DET
asodahs-27	301	9	synthesized	synthesize	VERB
asodahs-27	301	10	oxidovanadium(iv	oxidovanadium(iv	ADJ
asodahs-27	301	11	)	)	PUNCT
asodahs-27	301	12	complexes	complex	NOUN
asodahs-27	301	13	with	with	ADP
asodahs-27	301	14	an	an	DET
asodahs-27	301	15	increase	increase	NOUN
asodahs-27	301	16	in	in	ADP
asodahs-27	301	17	ct	ct	ADJ
asodahs-27	301	18	-	-	PUNCT
asodahs-27	301	19	dna	dna	PROPN
asodahs-27	301	20	concentration	concentration	NOUN
asodahs-27	301	21	,	,	PUNCT
asodahs-27	301	22	hyperchromic	hyperchromic	ADJ
asodahs-27	301	23	with	with	ADP
asodahs-27	301	24	electrostatic	electrostatic	ADJ
asodahs-27	301	25	or	or	CCONJ
asodahs-27	301	26	grooves	groove	VERB
asodahs-27	301	27	binding	bind	VERB
asodahs-27	301	28	modes	mode	NOUN
asodahs-27	301	29	and	and	CCONJ
asodahs-27	301	30	hypochromic	hypochromic	ADJ
asodahs-27	301	31	signifying	signify	VERB
asodahs-27	301	32	an	an	DET
asodahs-27	301	33	intercalation	intercalation	NOUN
asodahs-27	301	34	binding	bind	VERB
asodahs-27	301	35	mode	mode	NOUN
asodahs-27	301	36	.	.	PUNCT
asodahs-27	302	1	molecular	molecular	ADJ
asodahs-27	302	2	docking	docking	NOUN
asodahs-27	302	3	results	result	NOUN
asodahs-27	302	4	showed	show	VERB
asodahs-27	302	5	that	that	SCONJ
asodahs-27	302	6	the	the	DET
asodahs-27	302	7	[	[	X
asodahs-27	302	8	vo	vo	X
asodahs-27	302	9	(	(	PUNCT
asodahs-27	302	10	ctz)2	ctz)2	PROPN
asodahs-27	302	11	]	]	PUNCT
asodahs-27	302	12	2h2o	2h2o	NUM
asodahs-27	302	13	complex	complex	NOUN
asodahs-27	302	14	exhibited	exhibit	VERB
asodahs-27	302	15	significant	significant	ADJ
asodahs-27	302	16	interaction	interaction	NOUN
asodahs-27	302	17	with	with	ADP
asodahs-27	302	18	colon	colon	NOUN
asodahs-27	302	19	cancer	cancer	NOUN
asodahs-27	302	20	(	(	PUNCT
asodahs-27	302	21	3ig7	3ig7	NOUN
asodahs-27	302	22	)	)	PUNCT
asodahs-27	302	23	protein	protein	NOUN
asodahs-27	302	24	with	with	ADP
asodahs-27	302	25	good	good	ADJ
asodahs-27	302	26	selectivity	selectivity	NOUN
asodahs-27	302	27	.	.	PUNCT
asodahs-27	303	1	qsar	qsar	PROPN
asodahs-27	303	2	study	study	NOUN
asodahs-27	303	3	has	have	AUX
asodahs-27	303	4	given	give	VERB
asodahs-27	303	5	significant	significant	ADJ
asodahs-27	303	6	information	information	NOUN
asodahs-27	303	7	ahirwar	ahirwar	NOUN
asodahs-27	303	8	et	et	PROPN
asodahs-27	303	9	al	al	PROPN
asodahs-27	303	10	asian	asian	PROPN
asodahs-27	303	11	journal	journal	PROPN
asodahs-27	303	12	of	of	ADP
asodahs-27	303	13	dental	dental	ADJ
asodahs-27	303	14	and	and	CCONJ
asodahs-27	303	15	health	health	NOUN
asodahs-27	303	16	sciences	science	NOUN
asodahs-27	303	17	.	.	PUNCT
asodahs-27	303	18	2022	2022	NUM
asodahs-27	303	19	;	;	PUNCT
asodahs-27	303	20	2(4):59	2(4):59	NUM
asodahs-27	303	21	-	-	SYM
asodahs-27	303	22	63	63	NUM
asodahs-27	303	23	[	[	X
asodahs-27	303	24	61	61	NUM
asodahs-27	303	25	]	]	PUNCT
asodahs-27	303	26	ajdhs.com	ajdhs.com	X
asodahs-27	303	27	on	on	ADP
asodahs-27	303	28	biological	biological	ADJ
asodahs-27	303	29	activity	activity	NOUN
asodahs-27	303	30	by	by	ADP
asodahs-27	303	31	using	use	VERB
asodahs-27	303	32	the	the	DET
asodahs-27	303	33	mlr	mlr	NOUN
asodahs-27	303	34	method	method	NOUN
asodahs-27	303	35	.	.	PUNCT
asodahs-27	304	1	qsar	qsar	PROPN
asodahs-27	304	2	model	model	NOUN
asodahs-27	304	3	showed	show	VERB
asodahs-27	304	4	a	a	DET
asodahs-27	304	5	good	good	ADJ
asodahs-27	304	6	correlation	correlation	NOUN
asodahs-27	304	7	between	between	ADP
asodahs-27	304	8	the	the	DET
asodahs-27	304	9	predicted	predict	VERB
asodahs-27	304	10	and	and	CCONJ
asodahs-27	304	11	the	the	DET
asodahs-27	304	12	experimentally	experimentally	ADV
asodahs-27	304	13	observed	observe	VERB
asodahs-27	304	14	inhibitory	inhibitory	ADJ
asodahs-27	304	15	activities	activity	NOUN
asodahs-27	304	16	.	.	PUNCT
asodahs-27	305	1	the	the	DET
asodahs-27	305	2	results	result	NOUN
asodahs-27	305	3	of	of	ADP
asodahs-27	305	4	validation	validation	NOUN
asodahs-27	305	5	indicate	indicate	VERB
asodahs-27	305	6	that	that	SCONJ
asodahs-27	305	7	the	the	DET
asodahs-27	305	8	generated	generate	VERB
asodahs-27	305	9	qsar	qsar	PROPN
asodahs-27	305	10	model	model	NOUN
asodahs-27	305	11	possessed	possess	VERB
asodahs-27	305	12	a	a	DET
asodahs-27	305	13	high	high	ADJ
asodahs-27	305	14	predictive	predictive	ADJ
asodahs-27	305	15	power	power	NOUN
asodahs-27	305	16	(	(	PUNCT
asodahs-27	305	17	r2	r2	NOUN
asodahs-27	305	18	=	=	NOUN
asodahs-27	305	19	0.97	0.97	NUM
asodahs-27	305	20	)	)	PUNCT
asodahs-27	305	21	.	.	PUNCT
asodahs-27	306	1	based	base	VERB
asodahs-27	306	2	on	on	ADP
asodahs-27	306	3	the	the	DET
asodahs-27	306	4	molecular	molecular	ADJ
asodahs-27	306	5	docking	docking	NOUN
asodahs-27	306	6	and	and	CCONJ
asodahs-27	306	7	qsar	qsar	NOUN
asodahs-27	306	8	results	result	NOUN
asodahs-27	306	9	,	,	PUNCT
asodahs-27	306	10	[	[	X
asodahs-27	306	11	vo(ctz)2	vo(ctz)2	NOUN
asodahs-27	306	12	]	]	PUNCT
asodahs-27	306	13	2h2o	2h2o	NOUN
asodahs-27	306	14	was	be	AUX
asodahs-27	306	15	selected	select	VERB
asodahs-27	306	16	and	and	CCONJ
asodahs-27	306	17	tested	test	VERB
asodahs-27	306	18	for	for	ADP
asodahs-27	306	19	its	its	PRON
asodahs-27	306	20	inhibitory	inhibitory	ADJ
asodahs-27	306	21	activity	activity	NOUN
asodahs-27	306	22	against	against	ADP
asodahs-27	306	23	colon	colon	NOUN
asodahs-27	306	24	cancer	cancer	NOUN
asodahs-27	306	25	cell	cell	NOUN
asodahs-27	306	26	line	line	NOUN
asodahs-27	306	27	(	(	PUNCT
asodahs-27	306	28	hct116	hct116	PROPN
asodahs-27	306	29	)	)	PUNCT
asodahs-27	306	30	.	.	PUNCT
asodahs-27	307	1	the	the	DET
asodahs-27	307	2	selected	select	VERB
asodahs-27	307	3	complex	complex	NOUN
asodahs-27	307	4	showed	show	VERB
asodahs-27	307	5	higher	high	ADJ
asodahs-27	307	6	anticancer	anticancer	NOUN
asodahs-27	307	7	activity	activity	NOUN
asodahs-27	307	8	than	than	ADP
asodahs-27	307	9	the	the	DET
asodahs-27	307	10	standard	standard	ADJ
asodahs-27	307	11	cisplatin	cisplatin	NOUN
asodahs-27	307	12	chemotherapy	chemotherapy	NOUN
asodahs-27	307	13	drug26	drug26	NOUN
asodahs-27	307	14	.	.	PUNCT
asodahs-27	308	1	in	in	ADP
asodahs-27	308	2	an	an	DET
asodahs-27	308	3	another	another	DET
asodahs-27	308	4	research	research	NOUN
asodahs-27	308	5	qsar	qsar	NOUN
asodahs-27	308	6	and	and	CCONJ
asodahs-27	308	7	qaar	qaar	NOUN
asodahs-27	308	8	studies	study	NOUN
asodahs-27	308	9	have	have	AUX
asodahs-27	308	10	been	be	AUX
asodahs-27	308	11	conducted	conduct	VERB
asodahs-27	308	12	on	on	ADP
asodahs-27	308	13	diverse	diverse	ADJ
asodahs-27	308	14	benzamide	benzamide	NOUN
asodahs-27	308	15	-	-	PUNCT
asodahs-27	308	16	derived	derive	VERB
asodahs-27	308	17	hdac3	hdac3	NOUN
asodahs-27	308	18	inhibitors	inhibitor	NOUN
asodahs-27	308	19	as	as	ADP
asodahs-27	308	20	the	the	DET
asodahs-27	308	21	first	first	ADJ
asodahs-27	308	22	initiative	initiative	NOUN
asodahs-27	308	23	to	to	PART
asodahs-27	308	24	explore	explore	VERB
asodahs-27	308	25	the	the	DET
asodahs-27	308	26	designing	design	VERB
asodahs-27	308	27	strategies	strategy	NOUN
asodahs-27	308	28	of	of	ADP
asodahs-27	308	29	higher	high	ADJ
asodahs-27	308	30	active	active	ADJ
asodahs-27	308	31	and	and	CCONJ
asodahs-27	308	32	selective	selective	ADJ
asodahs-27	308	33	hdac3	hdac3	NOUN
asodahs-27	308	34	inhibitors	inhibitor	NOUN
asodahs-27	308	35	over	over	ADP
asodahs-27	308	36	hdac1	hdac1	NOUN
asodahs-27	308	37	and	and	CCONJ
asodahs-27	308	38	hdac2	hdac2	NOUN
asodahs-27	308	39	.	.	PUNCT
asodahs-27	309	1	qsar	qsar	PROPN
asodahs-27	309	2	models	model	NOUN
asodahs-27	309	3	reveal	reveal	VERB
asodahs-27	309	4	that	that	SCONJ
asodahs-27	309	5	molecular	molecular	ADJ
asodahs-27	309	6	size	size	NOUN
asodahs-27	309	7	and	and	CCONJ
asodahs-27	309	8	shape	shape	NOUN
asodahs-27	309	9	along	along	ADP
asodahs-27	309	10	with	with	ADP
asodahs-27	309	11	the	the	DET
asodahs-27	309	12	steric	steric	ADJ
asodahs-27	309	13	effect	effect	NOUN
asodahs-27	309	14	should	should	AUX
asodahs-27	309	15	have	have	VERB
asodahs-27	309	16	to	to	PART
asodahs-27	309	17	be	be	AUX
asodahs-27	309	18	optimized	optimize	VERB
asodahs-27	309	19	to	to	PART
asodahs-27	309	20	achieve	achieve	VERB
asodahs-27	309	21	higher	high	ADJ
asodahs-27	309	22	hdac3	hdac3	NOUN
asodahs-27	309	23	inhibition	inhibition	NOUN
asodahs-27	309	24	.	.	PUNCT
asodahs-27	310	1	qaar	qaar	NOUN
asodahs-27	310	2	models	model	NOUN
asodahs-27	310	3	reflect	reflect	VERB
asodahs-27	310	4	that	that	SCONJ
asodahs-27	310	5	modification	modification	NOUN
asodahs-27	310	6	/	/	SYM
asodahs-27	310	7	substitution	substitution	NOUN
asodahs-27	310	8	at	at	ADP
asodahs-27	310	9	the	the	DET
asodahs-27	310	10	benzamide	benzamide	NOUN
asodahs-27	310	11	scaffold	scaffold	NOUN
asodahs-27	310	12	should	should	AUX
asodahs-27	310	13	be	be	AUX
asodahs-27	310	14	optimized	optimize	VERB
asodahs-27	310	15	in	in	ADP
asodahs-27	310	16	such	such	DET
asodahs-27	310	17	a	a	DET
asodahs-27	310	18	way	way	NOUN
asodahs-27	310	19	so	so	SCONJ
asodahs-27	310	20	that	that	SCONJ
asodahs-27	310	21	these	these	DET
asodahs-27	310	22	molecules	molecule	NOUN
asodahs-27	310	23	possess	possess	VERB
asodahs-27	310	24	lower	low	ADJ
asodahs-27	310	25	steric	steric	ADJ
asodahs-27	310	26	bulk	bulk	NOUN
asodahs-27	310	27	along	along	ADP
asodahs-27	310	28	with	with	ADP
asodahs-27	310	29	nonpolar	nonpolar	ADJ
asodahs-27	310	30	features	feature	NOUN
asodahs-27	310	31	for	for	ADP
asodahs-27	310	32	achieving	achieve	VERB
asodahs-27	310	33	higher	high	ADJ
asodahs-27	310	34	hdac3	hdac3	NOUN
asodahs-27	311	1	selectivity	selectivity	NOUN
asodahs-27	311	2	over	over	ADP
asodahs-27	311	3	hdac1	hdac1	NOUN
asodahs-27	311	4	and	and	CCONJ
asodahs-27	311	5	hdac2	hdac2	NOUN
asodahs-27	311	6	.	.	PUNCT
asodahs-27	312	1	however	however	ADV
asodahs-27	312	2	,	,	PUNCT
asodahs-27	312	3	the	the	DET
asodahs-27	312	4	importance	importance	NOUN
asodahs-27	312	5	of	of	ADP
asodahs-27	312	6	spiro	spiro	NOUN
asodahs-27	312	7	hydrophobic	hydrophobic	NOUN
asodahs-27	312	8	cap	cap	NOUN
asodahs-27	312	9	group	group	NOUN
asodahs-27	312	10	,	,	PUNCT
asodahs-27	312	11	as	as	ADV
asodahs-27	312	12	well	well	ADV
asodahs-27	312	13	as	as	ADP
asodahs-27	312	14	electron	electron	NOUN
asodahs-27	312	15	withdrawing	withdraw	VERB
asodahs-27	312	16	fluorine	fluorine	NOUN
asodahs-27	312	17	group	group	NOUN
asodahs-27	312	18	at	at	ADP
asodahs-27	312	19	the	the	DET
asodahs-27	312	20	benzamide	benzamide	NOUN
asodahs-27	312	21	scaffold	scaffold	NOUN
asodahs-27	312	22	,	,	PUNCT
asodahs-27	312	23	should	should	AUX
asodahs-27	312	24	be	be	AUX
asodahs-27	312	25	well	well	ADV
asodahs-27	312	26	-	-	PUNCT
asodahs-27	312	27	accounted	account	VERB
asodahs-27	312	28	for	for	ADP
asodahs-27	312	29	retaining	retain	VERB
asodahs-27	312	30	higher	high	ADJ
asodahs-27	312	31	hdac3	hdac3	NOUN
asodahs-27	312	32	selectivity	selectivity	NOUN
asodahs-27	312	33	over	over	ADP
asodahs-27	312	34	hdac1	hdac1	NOUN
asodahs-27	312	35	.	.	PUNCT
asodahs-27	313	1	moreover	moreover	ADV
asodahs-27	313	2	,	,	PUNCT
asodahs-27	313	3	less	less	ADV
asodahs-27	313	4	polar	polar	ADJ
asodahs-27	313	5	and	and	CCONJ
asodahs-27	313	6	less	less	ADV
asodahs-27	313	7	hydrophobic	hydrophobic	NOUN
asodahs-27	313	8	benzamides	benzamide	NOUN
asodahs-27	313	9	are	be	AUX
asodahs-27	313	10	preferred	prefer	VERB
asodahs-27	313	11	for	for	ADP
asodahs-27	313	12	hdac3	hdac3	NOUN
asodahs-27	313	13	selectivity	selectivity	NOUN
asodahs-27	313	14	over	over	ADP
asodahs-27	313	15	hdac2	hdac2	NOUN
asodahs-27	313	16	.	.	PUNCT
asodahs-27	314	1	this	this	DET
asodahs-27	314	2	detailed	detailed	ADJ
asodahs-27	314	3	structural	structural	ADJ
asodahs-27	314	4	exploration	exploration	NOUN
asodahs-27	314	5	will	will	AUX
asodahs-27	314	6	surely	surely	ADV
asodahs-27	314	7	unveil	unveil	VERB
asodahs-27	314	8	a	a	DET
asodahs-27	314	9	new	new	ADJ
asodahs-27	314	10	vista	vista	NOUN
asodahs-27	314	11	of	of	ADP
asodahs-27	314	12	designing	design	VERB
asodahs-27	314	13	highly	highly	ADV
asodahs-27	314	14	potent	potent	ADJ
asodahs-27	314	15	and	and	CCONJ
asodahs-27	314	16	selective	selective	ADJ
asodahs-27	314	17	benzamide	benzamide	NOUN
asodahs-27	314	18	-	-	PUNCT
asodahs-27	314	19	based	base	VERB
asodahs-27	314	20	hdac3	hdac3	NOUN
asodahs-27	314	21	inhibitors	inhibitor	NOUN
asodahs-27	314	22	that	that	PRON
asodahs-27	314	23	may	may	AUX
asodahs-27	314	24	be	be	AUX
asodahs-27	314	25	a	a	DET
asodahs-27	314	26	crucial	crucial	ADJ
asodahs-27	314	27	weapon	weapon	NOUN
asodahs-27	314	28	to	to	ADP
asodahs-27	314	29	battle	battle	NOUN
asodahs-27	314	30	against	against	ADP
asodahs-27	314	31	a	a	DET
asodahs-27	314	32	variety	variety	NOUN
asodahs-27	314	33	of	of	ADP
asodahs-27	314	34	cancers27	cancers27	NOUN
asodahs-27	314	35	.	.	PUNCT
asodahs-27	315	1	ahirwar	ahirwar	PROPN
asodahs-27	315	2	et	et	PROPN
asodahs-27	315	3	al	al	PROPN
asodahs-27	315	4	asian	asian	PROPN
asodahs-27	315	5	journal	journal	PROPN
asodahs-27	315	6	of	of	ADP
asodahs-27	315	7	dental	dental	ADJ
asodahs-27	315	8	and	and	CCONJ
asodahs-27	315	9	health	health	NOUN
asodahs-27	315	10	sciences	science	NOUN
asodahs-27	315	11	.	.	PUNCT
asodahs-27	315	12	2022	2022	NUM
asodahs-27	315	13	;	;	PUNCT
asodahs-27	315	14	2(4):59	2(4):59	NUM
asodahs-27	315	15	-	-	SYM
asodahs-27	315	16	63	63	NUM
asodahs-27	316	1	[	[	X
asodahs-27	316	2	62	62	NUM
asodahs-27	316	3	]	]	PUNCT
asodahs-27	316	4	ajdhs.com	ajdhs.com	X
asodahs-27	316	5	an	an	DET
asodahs-27	316	6	example	example	NOUN
asodahs-27	316	7	of	of	ADP
asodahs-27	316	8	qsar	qsar	NOUN
asodahs-27	316	9	studies	study	NOUN
asodahs-27	316	10	,	,	PUNCT
asodahs-27	316	11	to	to	PART
asodahs-27	316	12	design	design	VERB
asodahs-27	316	13	new	new	ADJ
asodahs-27	316	14	molecules	molecule	NOUN
asodahs-27	316	15	with	with	ADP
asodahs-27	316	16	anticancer	anticancer	NOUN
asodahs-27	316	17	activity	activity	NOUN
asodahs-27	316	18	,	,	PUNCT
asodahs-27	316	19	two	two	NUM
asodahs-27	316	20	3d	3d	NUM
asodahs-27	316	21	qsar	qsar	NOUN
asodahs-27	316	22	models	model	NOUN
asodahs-27	316	23	was	be	AUX
asodahs-27	316	24	developed	develop	VERB
asodahs-27	316	25	:	:	PUNCT
asodahs-27	316	26	comfa	comfa	NOUN
asodahs-27	316	27	(	(	PUNCT
asodahs-27	316	28	q2	q2	NOUN
asodahs-27	316	29	=	=	SYM
asodahs-27	316	30	7.32	7.32	NUM
asodahs-27	316	31	,	,	PUNCT
asodahs-27	316	32	r2	r2	PROPN
asodahs-27	316	33	=	=	SYM
asodahs-27	316	34	9.92	9.92	NUM
asodahs-27	316	35	)	)	PUNCT
asodahs-27	316	36	and	and	CCONJ
asodahs-27	316	37	comsia	comsia	NOUN
asodahs-27	316	38	(	(	PUNCT
asodahs-27	316	39	q2	q2	NOUN
asodahs-27	316	40	=	=	SYM
asodahs-27	316	41	7.32	7.32	NUM
asodahs-27	316	42	,	,	PUNCT
asodahs-27	316	43	r2	r2	PROPN
asodahs-27	316	44	=	=	SYM
asodahs-27	316	45	9.92	9.92	NUM
asodahs-27	316	46	)	)	PUNCT
asodahs-27	316	47	based	base	VERB
asodahs-27	316	48	on	on	ADP
asodahs-27	316	49	42	42	NUM
asodahs-27	316	50	pyrazole	pyrazole	NOUN
asodahs-27	316	51	derivatives	derivative	NOUN
asodahs-27	316	52	.	.	PUNCT
asodahs-27	317	1	the	the	DET
asodahs-27	317	2	results	result	NOUN
asodahs-27	317	3	obtained	obtain	VERB
asodahs-27	317	4	for	for	ADP
asodahs-27	317	5	both	both	DET
asodahs-27	317	6	models	model	NOUN
asodahs-27	317	7	were	be	AUX
asodahs-27	317	8	satisfactory	satisfactory	ADJ
asodahs-27	317	9	and	and	CCONJ
asodahs-27	317	10	validated	validate	VERB
asodahs-27	317	11	by	by	ADP
asodahs-27	317	12	reliable	reliable	ADJ
asodahs-27	317	13	methods	method	NOUN
asodahs-27	317	14	.	.	PUNCT
asodahs-27	318	1	all	all	DET
asodahs-27	318	2	the	the	DET
asodahs-27	318	3	newly	newly	ADV
asodahs-27	318	4	designed	design	VERB
asodahs-27	318	5	molecules	molecule	NOUN
asodahs-27	318	6	respect	respect	VERB
asodahs-27	318	7	the	the	DET
asodahs-27	318	8	different	different	ADJ
asodahs-27	318	9	drug	drug	NOUN
asodahs-27	318	10	-	-	PUNCT
asodahs-27	318	11	likeness	likeness	NOUN
asodahs-27	318	12	rules	rule	NOUN
asodahs-27	318	13	(	(	PUNCT
asodahs-27	318	14	lipinski	lipinski	PROPN
asodahs-27	318	15	,	,	PUNCT
asodahs-27	318	16	veber	veber	PROPN
asodahs-27	318	17	,	,	PUNCT
asodahs-27	318	18	ghose	ghose	PROPN
asodahs-27	318	19	,	,	PUNCT
asodahs-27	318	20	egan	egan	PROPN
asodahs-27	318	21	,	,	PUNCT
asodahs-27	318	22	muegge	muegge	NOUN
asodahs-27	318	23	,	,	PUNCT
asodahs-27	318	24	and	and	CCONJ
asodahs-27	318	25	admet	admet	PROPN
asodahs-27	318	26	prediction	prediction	NOUN
asodahs-27	318	27	)	)	PUNCT
asodahs-27	318	28	.	.	PUNCT
asodahs-27	319	1	moreover	moreover	ADV
asodahs-27	319	2	,	,	PUNCT
asodahs-27	319	3	molecular	molecular	ADJ
asodahs-27	319	4	docking	docking	NOUN
asodahs-27	319	5	studies	study	NOUN
asodahs-27	319	6	results	result	VERB
asodahs-27	319	7	on	on	ADP
asodahs-27	319	8	egfr	egfr	ADJ
asodahs-27	319	9	receptor	receptor	NOUN
asodahs-27	319	10	indicated	indicate	VERB
asodahs-27	319	11	that	that	SCONJ
asodahs-27	319	12	the	the	DET
asodahs-27	319	13	interaction	interaction	NOUN
asodahs-27	319	14	results	result	NOUN
asodahs-27	319	15	of	of	ADP
asodahs-27	319	16	the	the	DET
asodahs-27	319	17	designed	design	VERB
asodahs-27	319	18	compounds	compound	NOUN
asodahs-27	319	19	t1	t1	PROPN
asodahs-27	319	20	-	-	PUNCT
asodahs-27	319	21	t5	t5	PROPN
asodahs-27	319	22	in	in	ADP
asodahs-27	319	23	the	the	DET
asodahs-27	319	24	cavity	cavity	NOUN
asodahs-27	319	25	of	of	ADP
asodahs-27	319	26	the	the	DET
asodahs-27	319	27	egfr	egfr	ADJ
asodahs-27	319	28	receptor	receptor	NOUN
asodahs-27	319	29	(	(	PUNCT
asodahs-27	319	30	1	1	NUM
asodahs-27	319	31	m17	m17	NUM
asodahs-27	319	32	)	)	PUNCT
asodahs-27	319	33	show	show	VERB
asodahs-27	319	34	more	more	ADJ
asodahs-27	319	35	type	type	NOUN
asodahs-27	319	36	and	and	CCONJ
asodahs-27	319	37	the	the	DET
asodahs-27	319	38	number	number	NOUN
asodahs-27	319	39	of	of	ADP
asodahs-27	319	40	interactions	interaction	NOUN
asodahs-27	319	41	(	(	PUNCT
asodahs-27	319	42	hydrogen	hydrogen	NOUN
asodahs-27	319	43	bond	bond	NOUN
asodahs-27	319	44	interaction	interaction	NOUN
asodahs-27	319	45	)	)	PUNCT
asodahs-27	319	46	compared	compare	VERB
asodahs-27	319	47	to	to	ADP
asodahs-27	319	48	erlotinib	erlotinib	NOUN
asodahs-27	319	49	as	as	ADP
asodahs-27	319	50	reference	reference	NOUN
asodahs-27	319	51	inhibitors	inhibitor	NOUN
asodahs-27	319	52	of	of	ADP
asodahs-27	319	53	egfr	egfr	NOUN
asodahs-27	319	54	.	.	PUNCT
asodahs-27	320	1	together	together	ADV
asodahs-27	320	2	,	,	PUNCT
asodahs-27	320	3	these	these	DET
asodahs-27	320	4	results	result	NOUN
asodahs-27	320	5	facilitate	facilitate	VERB
asodahs-27	320	6	and	and	CCONJ
asodahs-27	320	7	guide	guide	VERB
asodahs-27	320	8	the	the	DET
asodahs-27	320	9	design	design	NOUN
asodahs-27	320	10	and	and	CCONJ
asodahs-27	320	11	synthesis	synthesis	NOUN
asodahs-27	320	12	of	of	ADP
asodahs-27	320	13	novel	novel	NOUN
asodahs-27	320	14	and	and	CCONJ
asodahs-27	320	15	more	more	ADV
asodahs-27	320	16	potent	potent	ADJ
asodahs-27	320	17	pyrazole	pyrazole	NOUN
asodahs-27	320	18	derivatives	derivative	NOUN
asodahs-27	320	19	with	with	ADP
asodahs-27	320	20	anticancer	anticancer	NOUN
asodahs-27	320	21	activity28	activity28	NOUN
asodahs-27	320	22	.	.	PUNCT
asodahs-27	321	1	conclusion	conclusion	NOUN
asodahs-27	321	2	cancer	cancer	NOUN
asodahs-27	321	3	has	have	AUX
asodahs-27	321	4	become	become	VERB
asodahs-27	321	5	a	a	DET
asodahs-27	321	6	tangible	tangible	ADJ
asodahs-27	321	7	threat	threat	NOUN
asodahs-27	321	8	to	to	ADP
asodahs-27	321	9	human	human	ADJ
asodahs-27	321	10	health	health	NOUN
asodahs-27	321	11	.	.	PUNCT
asodahs-27	322	1	about	about	ADV
asodahs-27	322	2	9.6	9.6	NUM
asodahs-27	322	3	million	million	NUM
asodahs-27	322	4	people	people	NOUN
asodahs-27	322	5	are	be	AUX
asodahs-27	322	6	estimated	estimate	VERB
asodahs-27	322	7	to	to	PART
asodahs-27	322	8	die	die	VERB
asodahs-27	322	9	from	from	ADP
asodahs-27	322	10	the	the	DET
asodahs-27	322	11	various	various	ADJ
asodahs-27	322	12	forms	form	NOUN
asodahs-27	322	13	of	of	ADP
asodahs-27	322	14	cancer	cancer	NOUN
asodahs-27	322	15	each	each	DET
asodahs-27	322	16	year	year	NOUN
asodahs-27	322	17	,	,	PUNCT
asodahs-27	322	18	according	accord	VERB
asodahs-27	322	19	to	to	ADP
asodahs-27	322	20	a	a	DET
asodahs-27	322	21	statistic	statistic	ADJ
asodahs-27	322	22	report	report	NOUN
asodahs-27	322	23	.	.	PUNCT
asodahs-27	323	1	cancer	cancer	NOUN
asodahs-27	323	2	has	have	AUX
asodahs-27	323	3	become	become	VERB
asodahs-27	323	4	the	the	DET
asodahs-27	323	5	second	second	ADV
asodahs-27	323	6	-	-	PUNCT
asodahs-27	323	7	largest	large	ADJ
asodahs-27	323	8	disease	disease	NOUN
asodahs-27	323	9	that	that	PRON
asodahs-27	323	10	causes	cause	VERB
asodahs-27	323	11	human	human	ADJ
asodahs-27	323	12	death	death	NOUN
asodahs-27	323	13	.	.	PUNCT
asodahs-27	324	1	however	however	ADV
asodahs-27	324	2	,	,	PUNCT
asodahs-27	324	3	developing	develop	VERB
asodahs-27	324	4	a	a	DET
asodahs-27	324	5	new	new	ADJ
asodahs-27	324	6	drug	drug	NOUN
asodahs-27	324	7	molecule	molecule	NOUN
asodahs-27	324	8	costs	cost	NOUN
asodahs-27	324	9	12	12	NUM
asodahs-27	324	10	years	year	NOUN
asodahs-27	324	11	and	and	CCONJ
asodahs-27	324	12	2.7	2.7	NUM
asodahs-27	324	13	billion	billion	NUM
asodahs-27	324	14	usd	usd	NOUN
asodahs-27	324	15	on	on	ADP
asodahs-27	324	16	average	average	ADJ
asodahs-27	324	17	.	.	PUNCT
asodahs-27	325	1	the	the	DET
asodahs-27	325	2	drug	drug	NOUN
asodahs-27	325	3	development	development	NOUN
asodahs-27	325	4	for	for	ADP
asodahs-27	325	5	cancer	cancer	NOUN
asodahs-27	325	6	even	even	ADV
asodahs-27	325	7	becomes	become	VERB
asodahs-27	325	8	more	more	ADV
asodahs-27	325	9	complicated	complicated	ADJ
asodahs-27	325	10	,	,	PUNCT
asodahs-27	325	11	especially	especially	ADV
asodahs-27	325	12	considering	consider	VERB
asodahs-27	325	13	the	the	DET
asodahs-27	325	14	molecular	molecular	ADJ
asodahs-27	325	15	pharmacology	pharmacology	NOUN
asodahs-27	325	16	is	be	AUX
asodahs-27	325	17	still	still	ADV
asodahs-27	325	18	not	not	PART
asodahs-27	325	19	well	well	ADV
asodahs-27	325	20	understood	understand	VERB
asodahs-27	325	21	.	.	PUNCT
asodahs-27	326	1	hence	hence	ADV
asodahs-27	326	2	,	,	PUNCT
asodahs-27	326	3	the	the	DET
asodahs-27	326	4	discovery	discovery	NOUN
asodahs-27	326	5	and	and	CCONJ
asodahs-27	326	6	development	development	NOUN
asodahs-27	326	7	of	of	ADP
asodahs-27	326	8	new	new	ADJ
asodahs-27	326	9	drugs	drug	NOUN
asodahs-27	326	10	is	be	AUX
asodahs-27	326	11	considered	consider	VERB
asodahs-27	326	12	very	very	ADV
asodahs-27	326	13	expensive	expensive	ADJ
asodahs-27	326	14	and	and	CCONJ
asodahs-27	326	15	time	time	NOUN
asodahs-27	326	16	-	-	PUNCT
asodahs-27	326	17	consuming	consume	VERB
asodahs-27	326	18	.	.	PUNCT
asodahs-27	327	1	in	in	ADP
asodahs-27	327	2	this	this	DET
asodahs-27	327	3	respect	respect	NOUN
asodahs-27	327	4	,	,	PUNCT
asodahs-27	327	5	computational	computational	ADJ
asodahs-27	327	6	methods	method	NOUN
asodahs-27	327	7	could	could	AUX
asodahs-27	327	8	be	be	AUX
asodahs-27	327	9	constructive	constructive	ADJ
asodahs-27	327	10	for	for	ADP
asodahs-27	327	11	performing	perform	VERB
asodahs-27	327	12	different	different	ADJ
asodahs-27	327	13	tasks	task	NOUN
asodahs-27	327	14	including	include	VERB
asodahs-27	327	15	protein	protein	NOUN
asodahs-27	327	16	-	-	PUNCT
asodahs-27	327	17	interaction	interaction	NOUN
asodahs-27	327	18	network	network	NOUN
asodahs-27	327	19	analysis	analysis	NOUN
asodahs-27	327	20	,	,	PUNCT
asodahs-27	327	21	drug	drug	NOUN
asodahs-27	327	22	target	target	NOUN
asodahs-27	327	23	prediction	prediction	NOUN
asodahs-27	327	24	,	,	PUNCT
asodahs-27	327	25	binding	bind	VERB
asodahs-27	327	26	site	site	NOUN
asodahs-27	327	27	prediction	prediction	NOUN
asodahs-27	327	28	,	,	PUNCT
asodahs-27	327	29	virtual	virtual	ADJ
asodahs-27	327	30	screening	screening	NOUN
asodahs-27	327	31	,	,	PUNCT
asodahs-27	327	32	and	and	CCONJ
asodahs-27	327	33	many	many	ADJ
asodahs-27	327	34	others	other	NOUN
asodahs-27	327	35	.	.	PUNCT
asodahs-27	328	1	all	all	DET
asodahs-27	328	2	these	these	DET
asodahs-27	328	3	innovative	innovative	ADJ
asodahs-27	328	4	methods	method	NOUN
asodahs-27	328	5	could	could	AUX
asodahs-27	328	6	considerably	considerably	ADV
asodahs-27	328	7	facilitate	facilitate	VERB
asodahs-27	328	8	the	the	DET
asodahs-27	328	9	anti	anti	ADJ
asodahs-27	328	10	-	-	ADJ
asodahs-27	328	11	cancer	cancer	ADJ
asodahs-27	328	12	drug	drug	NOUN
asodahs-27	328	13	discovery	discovery	NOUN
asodahs-27	328	14	.	.	PUNCT
asodahs-27	329	1	in	in	ADP
asodahs-27	329	2	recent	recent	ADJ
asodahs-27	329	3	years	year	NOUN
asodahs-27	329	4	,	,	PUNCT
asodahs-27	329	5	with	with	SCONJ
asodahs-27	329	6	the	the	DET
asodahs-27	329	7	advance	advance	NOUN
asodahs-27	329	8	of	of	ADP
asodahs-27	329	9	ai	ai	NOUN
asodahs-27	329	10	,	,	PUNCT
asodahs-27	329	11	more	more	ADV
asodahs-27	329	12	sophisticated	sophisticated	ADJ
asodahs-27	329	13	methods	method	NOUN
asodahs-27	329	14	,	,	PUNCT
asodahs-27	329	15	such	such	ADJ
asodahs-27	329	16	as	as	ADP
asodahs-27	329	17	qsar	qsar	NOUN
asodahs-27	329	18	,	,	PUNCT
asodahs-27	329	19	retro	retro	ADJ
asodahs-27	329	20	-	-	PUNCT
asodahs-27	329	21	synthetic	synthetic	ADJ
asodahs-27	329	22	routine	routine	ADJ
asodahs-27	329	23	plan	plan	NOUN
asodahs-27	329	24	,	,	PUNCT
asodahs-27	329	25	drug	drug	NOUN
asodahs-27	329	26	scaffold	scaffold	NOUN
asodahs-27	329	27	generation	generation	NOUN
asodahs-27	329	28	,	,	PUNCT
asodahs-27	329	29	drug	drug	NOUN
asodahs-27	329	30	binding	bind	VERB
asodahs-27	329	31	affinity	affinity	NOUN
asodahs-27	329	32	predictions	prediction	NOUN
asodahs-27	329	33	,	,	PUNCT
asodahs-27	329	34	were	be	AUX
asodahs-27	329	35	developed	develop	VERB
asodahs-27	329	36	.	.	PUNCT
asodahs-27	330	1	the	the	DET
asodahs-27	330	2	useful	useful	ADJ
asodahs-27	330	3	predictions	prediction	NOUN
asodahs-27	330	4	generated	generate	VERB
asodahs-27	330	5	by	by	ADP
asodahs-27	330	6	qsar	qsar	NOUN
asodahs-27	330	7	models	model	NOUN
asodahs-27	330	8	combined	combine	VERB
asodahs-27	330	9	with	with	ADP
asodahs-27	330	10	experimental	experimental	ADJ
asodahs-27	330	11	validations	validation	NOUN
asodahs-27	330	12	could	could	AUX
asodahs-27	330	13	further	far	ADV
asodahs-27	330	14	speed	speed	VERB
asodahs-27	330	15	up	up	ADP
asodahs-27	330	16	the	the	DET
asodahs-27	330	17	anti	anti	ADJ
asodahs-27	330	18	-	-	ADJ
asodahs-27	330	19	cancer	cancer	ADJ
asodahs-27	330	20	drug	drug	NOUN
asodahs-27	330	21	development	development	NOUN
asodahs-27	330	22	.	.	PUNCT
asodahs-27	331	1	references	reference	NOUN
asodahs-27	331	2	1	1	NUM
asodahs-27	331	3	.	.	PUNCT
asodahs-27	331	4	yan	yan	PROPN
asodahs-27	332	1	b	b	PROPN
asodahs-27	332	2	,	,	PUNCT
asodahs-27	332	3	yang	yang	PROPN
asodahs-27	332	4	w	w	PROPN
asodahs-27	332	5	,	,	PUNCT
asodahs-27	332	6	han	han	PROPN
asodahs-27	332	7	x	x	PROPN
asodahs-27	332	8	,	,	PUNCT
asodahs-27	332	9	han	han	PROPN
asodahs-27	332	10	l.	l.	PROPN
asodahs-27	332	11	crystal	crystal	PROPN
asodahs-27	332	12	structures	structure	NOUN
asodahs-27	332	13	and	and	CCONJ
asodahs-27	332	14	antitumor	antitumor	NOUN
asodahs-27	332	15	activity	activity	NOUN
asodahs-27	332	16	evaluation	evaluation	NOUN
asodahs-27	332	17	against	against	ADP
asodahs-27	332	18	gastric	gastric	ADJ
asodahs-27	332	19	carcinoma	carcinoma	NOUN
asodahs-27	332	20	of	of	ADP
asodahs-27	332	21	two	two	NUM
asodahs-27	332	22	novel	novel	ADJ
asodahs-27	332	23	coordination	coordination	NOUN
asodahs-27	332	24	polymers	polymer	NOUN
asodahs-27	332	25	.	.	PUNCT
asodahs-27	333	1	main	main	ADJ
asodahs-27	333	2	group	group	NOUN
asodahs-27	333	3	chemistry	chemistry	NOUN
asodahs-27	333	4	.	.	PUNCT
asodahs-27	334	1	2019	2019	NUM
asodahs-27	334	2	;	;	PUNCT
asodahs-27	334	3	18(3):239246	18(3):239246	NUM
asodahs-27	334	4	.	.	PUNCT
asodahs-27	335	1	https://doi.org/10.3233/mgc-180748	https://doi.org/10.3233/mgc-180748	NOUN
asodahs-27	335	2	2	2	X
asodahs-27	335	3	.	.	X
asodahs-27	335	4	bray	bray	PROPN
asodahs-27	335	5	f	f	PROPN
asodahs-27	335	6	,	,	PUNCT
asodahs-27	335	7	ferlay	ferlay	PROPN
asodahs-27	335	8	j	j	PROPN
asodahs-27	335	9	,	,	PUNCT
asodahs-27	335	10	soerjomataram	soerjomataram	PROPN
asodahs-27	335	11	i	i	PROPN
asodahs-27	335	12	,	,	PUNCT
asodahs-27	335	13	siegel	siegel	PROPN
asodahs-27	335	14	rl	rl	PROPN
asodahs-27	335	15	,	,	PUNCT
asodahs-27	335	16	torre	torre	PROPN
asodahs-27	335	17	la	la	PROPN
asodahs-27	335	18	,	,	PUNCT
asodahs-27	335	19	jemal	jemal	ADJ
asodahs-27	335	20	a.	a.	PROPN
asodahs-27	335	21	global	global	PROPN
asodahs-27	335	22	cancer	cancer	PROPN
asodahs-27	335	23	statistics	statistic	NOUN
asodahs-27	335	24	2018	2018	NUM
asodahs-27	335	25	:	:	PUNCT
asodahs-27	335	26	globocan	globocan	PROPN
asodahs-27	335	27	estimates	estimate	NOUN
asodahs-27	335	28	of	of	ADP
asodahs-27	335	29	incidence	incidence	NOUN
asodahs-27	335	30	and	and	CCONJ
asodahs-27	335	31	mortality	mortality	NOUN
asodahs-27	335	32	worldwide	worldwide	ADV
asodahs-27	335	33	for	for	ADP
asodahs-27	335	34	36	36	NUM
asodahs-27	335	35	cancers	cancer	NOUN
asodahs-27	335	36	in	in	ADP
asodahs-27	335	37	185	185	NUM
asodahs-27	335	38	countries	country	NOUN
asodahs-27	335	39	.	.	PUNCT
asodahs-27	336	1	ca	can	AUX
asodahs-27	336	2	:	:	PUNCT
asodahs-27	336	3	a	a	DET
asodahs-27	336	4	cancer	cancer	NOUN
asodahs-27	336	5	journal	journal	NOUN
asodahs-27	336	6	for	for	ADP
asodahs-27	336	7	clinicians	clinician	NOUN
asodahs-27	336	8	.	.	PUNCT
asodahs-27	337	1	2018	2018	NUM
asodahs-27	337	2	;	;	PUNCT
asodahs-27	337	3	68(6):394	68(6):394	X
asodahs-27	337	4	-	-	SYM
asodahs-27	337	5	424	424	NUM
asodahs-27	337	6	.	.	PUNCT
asodahs-27	338	1	https://doi.org/10.3322/caac.21492	https://doi.org/10.3322/caac.21492	PRON
asodahs-27	338	2	3	3	X
asodahs-27	338	3	.	.	PUNCT
asodahs-27	338	4	kapetanovic	kapetanovic	PROPN
asodahs-27	338	5	i.	i.	PROPN
asodahs-27	338	6	computer	computer	NOUN
asodahs-27	338	7	-	-	PUNCT
asodahs-27	338	8	aided	aid	VERB
asodahs-27	338	9	drug	drug	NOUN
asodahs-27	338	10	discovery	discovery	NOUN
asodahs-27	338	11	and	and	CCONJ
asodahs-27	338	12	development	development	NOUN
asodahs-27	338	13	(	(	PUNCT
asodahs-27	338	14	caddd	caddd	PROPN
asodahs-27	338	15	):	):	PUNCT
asodahs-27	338	16	in	in	ADP
asodahs-27	338	17	silico	silico	NOUN
asodahs-27	338	18	-	-	PUNCT
asodahs-27	338	19	chemico	chemico	NOUN
asodahs-27	338	20	-	-	ADJ
asodahs-27	338	21	biological	biological	ADJ
asodahs-27	338	22	approach	approach	NOUN
asodahs-27	338	23	.	.	PUNCT
asodahs-27	339	1	chemicobiological	chemicobiological	ADJ
asodahs-27	339	2	interactions	interaction	NOUN
asodahs-27	339	3	.	.	PUNCT
asodahs-27	339	4	2008	2008	NUM
asodahs-27	339	5	;	;	PUNCT
asodahs-27	339	6	171(2):165	171(2):165	NUM
asodahs-27	339	7	-	-	SYM
asodahs-27	339	8	176	176	NUM
asodahs-27	339	9	.	.	PUNCT
asodahs-27	340	1	https://doi.org/10.1016/j.cbi.2006.12.006	https://doi.org/10.1016/j.cbi.2006.12.006	NOUN
asodahs-27	340	2	4	4	NUM
asodahs-27	340	3	.	.	PUNCT
asodahs-27	340	4	kaldor	kaldor	PROPN
asodahs-27	340	5	sw	sw	PROPN
asodahs-27	340	6	,	,	PUNCT
asodahs-27	340	7	kalish	kalish	PROPN
asodahs-27	340	8	vj	vj	PROPN
asodahs-27	340	9	,	,	PUNCT
asodahs-27	340	10	davies	davies	PROPN
asodahs-27	340	11	jf	jf	PROPN
asodahs-27	340	12	,	,	PUNCT
asodahs-27	340	13	shetty	shetty	PROPN
asodahs-27	340	14	bv	bv	PROPN
asodahs-27	340	15	,	,	PUNCT
asodahs-27	340	16	fritz	fritz	PROPN
asodahs-27	340	17	je	je	PROPN
asodahs-27	340	18	,	,	PUNCT
asodahs-27	340	19	appelt	appelt	VERB
asodahs-27	340	20	k	k	NOUN
asodahs-27	340	21	,	,	PUNCT
asodahs-27	340	22	tatlock	tatlock	PROPN
asodahs-27	340	23	jh	jh	PROPN
asodahs-27	340	24	.	.	PUNCT
asodahs-27	341	1	viracept	viracept	PROPN
asodahs-27	341	2	(	(	PUNCT
asodahs-27	341	3	nelfinavir	nelfinavir	ADV
asodahs-27	341	4	mesylate	mesylate	NOUN
asodahs-27	341	5	,	,	PUNCT
asodahs-27	341	6	ag1343	ag1343	PROPN
asodahs-27	341	7	):	):	PUNCT
asodahs-27	341	8	a	a	DET
asodahs-27	341	9	potent	potent	NOUN
asodahs-27	341	10	,	,	PUNCT
asodahs-27	341	11	orally	orally	ADV
asodahs-27	341	12	bioavailable	bioavailable	ADJ
asodahs-27	341	13	inhibitor	inhibitor	NOUN
asodahs-27	341	14	of	of	ADP
asodahs-27	341	15	hiv-1	hiv-1	X
asodahs-27	341	16	protease	protease	NOUN
asodahs-27	341	17	.	.	PUNCT
asodahs-27	342	1	journal	journal	NOUN
asodahs-27	342	2	of	of	ADP
asodahs-27	342	3	medicinal	medicinal	ADJ
asodahs-27	342	4	chemistry	chemistry	NOUN
asodahs-27	342	5	.	.	PUNCT
asodahs-27	343	1	1997	1997	NUM
asodahs-27	343	2	;	;	PUNCT
asodahs-27	343	3	40(24):3979	40(24):3979	X
asodahs-27	343	4	-	-	SYM
asodahs-27	343	5	3985	3985	NUM
asodahs-27	343	6	.	.	PUNCT
asodahs-27	344	1	https://doi.org/10.1021/jm9704098	https://doi.org/10.1021/jm9704098	PROPN
asodahs-27	345	1	5	5	X
asodahs-27	345	2	.	.	X
asodahs-27	345	3	chan	chan	PROPN
asodahs-27	345	4	hs	hs	PROPN
asodahs-27	345	5	,	,	PUNCT
asodahs-27	345	6	shan	shan	ADJ
asodahs-27	345	7	h	h	PROPN
asodahs-27	345	8	,	,	PUNCT
asodahs-27	345	9	dahoun	dahoun	PROPN
asodahs-27	345	10	t	t	PROPN
asodahs-27	345	11	,	,	PUNCT
asodahs-27	345	12	vogel	vogel	NOUN
asodahs-27	345	13	h	h	NOUN
asodahs-27	345	14	,	,	PUNCT
asodahs-27	345	15	yuan	yuan	PROPN
asodahs-27	345	16	s.	s.	PROPN
asodahs-27	345	17	advancing	advance	VERB
asodahs-27	345	18	drug	drug	NOUN
asodahs-27	345	19	discovery	discovery	NOUN
asodahs-27	345	20	via	via	ADP
asodahs-27	345	21	artificial	artificial	ADJ
asodahs-27	345	22	intelligence	intelligence	NOUN
asodahs-27	345	23	.	.	PUNCT
asodahs-27	346	1	trends	trend	NOUN
asodahs-27	346	2	in	in	ADP
asodahs-27	346	3	pharmacological	pharmacological	ADJ
asodahs-27	346	4	sciences	science	NOUN
asodahs-27	346	5	.	.	PUNCT
asodahs-27	347	1	2019	2019	NUM
asodahs-27	347	2	;	;	PUNCT
asodahs-27	347	3	40(8):592	40(8):592	PROPN
asodahs-27	347	4	-	-	SYM
asodahs-27	347	5	604	604	NUM
asodahs-27	347	6	.	.	PUNCT
asodahs-27	348	1	https://doi.org/10.1016/j.tips.2019.06.004	https://doi.org/10.1016/j.tips.2019.06.004	NUM
asodahs-27	348	2	6	6	NUM
asodahs-27	348	3	.	.	PUNCT
asodahs-27	348	4	yan	yan	PROPN
asodahs-27	349	1	b	b	PROPN
asodahs-27	349	2	,	,	PUNCT
asodahs-27	349	3	yang	yang	PROPN
asodahs-27	349	4	w	w	PROPN
asodahs-27	349	5	,	,	PUNCT
asodahs-27	349	6	han	han	PROPN
asodahs-27	349	7	x	x	PROPN
asodahs-27	349	8	,	,	PUNCT
asodahs-27	349	9	han	han	PROPN
asodahs-27	349	10	l.	l.	PROPN
asodahs-27	349	11	crystal	crystal	PROPN
asodahs-27	349	12	structures	structure	NOUN
asodahs-27	349	13	and	and	CCONJ
asodahs-27	349	14	antitumor	antitumor	NOUN
asodahs-27	349	15	activity	activity	NOUN
asodahs-27	349	16	evaluation	evaluation	NOUN
asodahs-27	349	17	against	against	ADP
asodahs-27	349	18	gastric	gastric	ADJ
asodahs-27	349	19	carcinoma	carcinoma	NOUN
asodahs-27	349	20	of	of	ADP
asodahs-27	349	21	two	two	NUM
asodahs-27	349	22	novel	novel	ADJ
asodahs-27	349	23	coordination	coordination	NOUN
asodahs-27	349	24	polymers	polymer	NOUN
asodahs-27	349	25	.	.	PUNCT
asodahs-27	350	1	main	main	ADJ
asodahs-27	350	2	group	group	NOUN
asodahs-27	350	3	chemistry	chemistry	NOUN
asodahs-27	350	4	.	.	PUNCT
asodahs-27	351	1	2019	2019	NUM
asodahs-27	351	2	;	;	PUNCT
asodahs-27	351	3	18(3):239246	18(3):239246	NUM
asodahs-27	351	4	.	.	PUNCT
asodahs-27	352	1	https://doi.org/10.3233/mgc-180748	https://doi.org/10.3233/mgc-180748	NOUN
asodahs-27	352	2	7	7	X
asodahs-27	352	3	.	.	PUNCT
asodahs-27	353	1	zhavoronkov	zhavoronkov	PROPN
asodahs-27	353	2	a	a	PRON
asodahs-27	353	3	,	,	PUNCT
asodahs-27	353	4	ivanenkov	ivanenkov	NOUN
asodahs-27	353	5	ya	ya	PROPN
asodahs-27	353	6	,	,	PUNCT
asodahs-27	353	7	aliper	aliper	PROPN
asodahs-27	353	8	a	a	PRON
asodahs-27	353	9	,	,	PUNCT
asodahs-27	353	10	veselov	veselov	NOUN
asodahs-27	353	11	ms	ms	PROPN
asodahs-27	353	12	,	,	PUNCT
asodahs-27	353	13	aladinskiy	aladinskiy	PROPN
asodahs-27	353	14	va	va	PROPN
asodahs-27	353	15	,	,	PUNCT
asodahs-27	353	16	aladinskaya	aladinskaya	NOUN
asodahs-27	353	17	av	av	NOUN
asodahs-27	353	18	,	,	PUNCT
asodahs-27	353	19	aspuru	aspuru	ADJ
asodahs-27	353	20	-	-	PUNCT
asodahs-27	353	21	guzik	guzik	NOUN
asodahs-27	353	22	a.	a.	NOUN
asodahs-27	353	23	deep	deep	ADJ
asodahs-27	353	24	learning	learning	NOUN
asodahs-27	353	25	enables	enable	VERB
asodahs-27	353	26	rapid	rapid	ADJ
asodahs-27	353	27	identification	identification	NOUN
asodahs-27	353	28	of	of	ADP
asodahs-27	353	29	potent	potent	ADJ
asodahs-27	353	30	ddr1	ddr1	PROPN
asodahs-27	353	31	kinase	kinase	PROPN
asodahs-27	353	32	inhibitors	inhibitor	NOUN
asodahs-27	353	33	.	.	PUNCT
asodahs-27	354	1	nature	nature	NOUN
asodahs-27	354	2	biotechnology	biotechnology	NOUN
asodahs-27	354	3	.	.	PUNCT
asodahs-27	355	1	2019	2019	NUM
asodahs-27	355	2	;	;	PUNCT
asodahs-27	355	3	37(9):1038	37(9):1038	NUM
asodahs-27	355	4	-	-	SYM
asodahs-27	355	5	1040	1040	NUM
asodahs-27	355	6	.	.	PUNCT
asodahs-27	356	1	https://doi.org/10.1038/s41587-019-0224-x	https://doi.org/10.1038/s41587-019-0224-x	PROPN
asodahs-27	356	2	8	8	NUM
asodahs-27	356	3	.	.	PUNCT
asodahs-27	357	1	drews	drews	PROPN
asodahs-27	357	2	j.	j.	PROPN
asodahs-27	357	3	drug	drug	PROPN
asodahs-27	357	4	discovery	discovery	PROPN
asodahs-27	357	5	:	:	PUNCT
asodahs-27	357	6	a	a	DET
asodahs-27	357	7	historical	historical	ADJ
asodahs-27	357	8	perspective	perspective	NOUN
asodahs-27	357	9	.	.	PUNCT
asodahs-27	358	1	science	science	NOUN
asodahs-27	358	2	.	.	PUNCT
asodahs-27	359	1	2000	2000	NUM
asodahs-27	359	2	;	;	PUNCT
asodahs-27	359	3	287(5460):1960	287(5460):1960	NUM
asodahs-27	359	4	-	-	SYM
asodahs-27	359	5	1964	1964	NUM
asodahs-27	359	6	.	.	PUNCT
asodahs-27	360	1	https://doi.org/10.1126/science.287.5460.1960	https://doi.org/10.1126/science.287.5460.1960	ADP
asodahs-27	360	2	9	9	NUM
asodahs-27	360	3	.	.	PUNCT
asodahs-27	361	1	chen	chen	PROPN
asodahs-27	361	2	x	x	PROPN
asodahs-27	361	3	,	,	PUNCT
asodahs-27	361	4	yan	yan	PROPN
asodahs-27	361	5	cc	cc	PROPN
asodahs-27	361	6	,	,	PUNCT
asodahs-27	361	7	zhang	zhang	PROPN
asodahs-27	361	8	x	x	PROPN
asodahs-27	361	9	,	,	PUNCT
asodahs-27	361	10	zhang	zhang	PROPN
asodahs-27	361	11	x	x	PROPN
asodahs-27	361	12	,	,	PUNCT
asodahs-27	361	13	dai	dai	PROPN
asodahs-27	361	14	f	f	PROPN
asodahs-27	361	15	,	,	PUNCT
asodahs-27	361	16	yin	yin	PROPN
asodahs-27	361	17	j	j	PROPN
asodahs-27	361	18	,	,	PUNCT
asodahs-27	361	19	zhang	zhang	PROPN
asodahs-27	361	20	y.	y.	PROPN
asodahs-27	361	21	drug	drug	PROPN
asodahs-27	361	22	-	-	PUNCT
asodahs-27	361	23	target	target	NOUN
asodahs-27	361	24	interaction	interaction	NOUN
asodahs-27	361	25	prediction	prediction	NOUN
asodahs-27	361	26	:	:	PUNCT
asodahs-27	361	27	databases	database	NOUN
asodahs-27	361	28	,	,	PUNCT
asodahs-27	361	29	web	web	NOUN
asodahs-27	361	30	servers	server	NOUN
asodahs-27	361	31	and	and	CCONJ
asodahs-27	361	32	computational	computational	ADJ
asodahs-27	361	33	models	model	NOUN
asodahs-27	361	34	.	.	PUNCT
asodahs-27	362	1	briefings	briefing	NOUN
asodahs-27	362	2	in	in	ADP
asodahs-27	362	3	bioinformatics	bioinformatics	NOUN
asodahs-27	362	4	.	.	PUNCT
asodahs-27	363	1	2016	2016	NUM
asodahs-27	363	2	;	;	PUNCT
asodahs-27	363	3	17(4):696	17(4):696	NUM
asodahs-27	363	4	-	-	SYM
asodahs-27	363	5	712	712	NUM
asodahs-27	363	6	.	.	PUNCT
asodahs-27	364	1	https://doi.org/10.1093/bib/bbv066	https://doi.org/10.1093/bib/bbv066	PROPN
asodahs-27	364	2	10	10	NUM
asodahs-27	364	3	.	.	PUNCT
asodahs-27	365	1	lazo	lazo	PROPN
asodahs-27	365	2	js	js	PROPN
asodahs-27	365	3	,	,	PUNCT
asodahs-27	365	4	sharlow	sharlow	NOUN
asodahs-27	365	5	er	er	INTJ
asodahs-27	365	6	.	.	PUNCT
asodahs-27	366	1	drugging	drug	VERB
asodahs-27	366	2	undruggable	undruggable	ADJ
asodahs-27	366	3	molecular	molecular	ADJ
asodahs-27	366	4	cancer	cancer	NOUN
asodahs-27	366	5	targets	target	NOUN
asodahs-27	366	6	.	.	PUNCT
asodahs-27	367	1	annual	annual	ADJ
asodahs-27	367	2	review	review	NOUN
asodahs-27	367	3	of	of	ADP
asodahs-27	367	4	pharmacology	pharmacology	NOUN
asodahs-27	367	5	and	and	CCONJ
asodahs-27	367	6	toxicology	toxicology	NOUN
asodahs-27	367	7	.	.	PUNCT
asodahs-27	368	1	2016	2016	NUM
asodahs-27	368	2	;	;	PUNCT
asodahs-27	368	3	56:23	56:23	NUM
asodahs-27	368	4	-	-	SYM
asodahs-27	368	5	40	40	NUM
asodahs-27	368	6	.	.	PUNCT
asodahs-27	369	1	https://doi.org/10.1146/annurev-pharmtox-010715103440	https://doi.org/10.1146/annurev-pharmtox-010715103440	PROPN
asodahs-27	369	2	11	11	NUM
asodahs-27	369	3	.	.	PUNCT
asodahs-27	370	1	hopkins	hopkins	PROPN
asodahs-27	370	2	al	al	PROPN
asodahs-27	370	3	.	.	PROPN
asodahs-27	370	4	network	network	PROPN
asodahs-27	370	5	pharmacology	pharmacology	NOUN
asodahs-27	370	6	:	:	PUNCT
asodahs-27	370	7	the	the	DET
asodahs-27	370	8	next	next	ADJ
asodahs-27	370	9	paradigm	paradigm	NOUN
asodahs-27	370	10	in	in	ADP
asodahs-27	370	11	drug	drug	NOUN
asodahs-27	370	12	discovery	discovery	NOUN
asodahs-27	370	13	.	.	PUNCT
asodahs-27	371	1	nature	nature	NOUN
asodahs-27	371	2	chemical	chemical	NOUN
asodahs-27	371	3	biology	biology	NOUN
asodahs-27	371	4	.	.	PUNCT
asodahs-27	372	1	2008	2008	NUM
asodahs-27	372	2	;	;	PUNCT
asodahs-27	372	3	4(11):682	4(11):682	PROPN
asodahs-27	372	4	-	-	PUNCT
asodahs-27	372	5	690	690	NUM
asodahs-27	372	6	.	.	PUNCT
asodahs-27	373	1	https://doi.org/10.1038/nchembio.118	https://doi.org/10.1038/nchembio.118	PROPN
asodahs-27	374	1	12	12	NUM
asodahs-27	374	2	.	.	PUNCT
asodahs-27	375	1	yamanishi	yamanishi	PROPN
asodahs-27	375	2	y	y	PROPN
asodahs-27	375	3	,	,	PUNCT
asodahs-27	375	4	araki	araki	PROPN
asodahs-27	375	5	m	m	PROPN
asodahs-27	375	6	,	,	PUNCT
asodahs-27	375	7	gutteridge	gutteridge	VERB
asodahs-27	375	8	a	a	PRON
asodahs-27	375	9	,	,	PUNCT
asodahs-27	375	10	honda	honda	PROPN
asodahs-27	375	11	w	w	PROPN
asodahs-27	375	12	,	,	PUNCT
asodahs-27	375	13	kanehisa	kanehisa	NOUN
asodahs-27	375	14	m.	m.	NOUN
asodahs-27	375	15	prediction	prediction	NOUN
asodahs-27	375	16	of	of	ADP
asodahs-27	375	17	drug	drug	NOUN
asodahs-27	375	18	-	-	PUNCT
asodahs-27	375	19	target	target	NOUN
asodahs-27	375	20	interaction	interaction	NOUN
asodahs-27	375	21	networks	network	NOUN
asodahs-27	375	22	from	from	ADP
asodahs-27	375	23	the	the	DET
asodahs-27	375	24	integration	integration	NOUN
asodahs-27	375	25	of	of	ADP
asodahs-27	375	26	chemical	chemical	ADJ
asodahs-27	375	27	and	and	CCONJ
asodahs-27	375	28	genomic	genomic	ADJ
asodahs-27	375	29	spaces	space	NOUN
asodahs-27	375	30	.	.	PUNCT
asodahs-27	376	1	bioinformatics	bioinformatics	NOUN
asodahs-27	376	2	.	.	PUNCT
asodahs-27	376	3	2008	2008	NUM
asodahs-27	376	4	;	;	PUNCT
asodahs-27	376	5	24(13):i232	24(13):i232	X
asodahs-27	376	6	-	-	PUNCT
asodahs-27	376	7	i240	i240	PROPN
asodahs-27	376	8	.	.	PUNCT
asodahs-27	376	9	https://doi.org/10.1093/bioinformatics/btn162	https://doi.org/10.1093/bioinformatics/btn162	PROPN
asodahs-27	376	10	13	13	NUM
asodahs-27	376	11	.	.	PUNCT
asodahs-27	377	1	rajak	rajak	PROPN
asodahs-27	377	2	h	h	PROPN
asodahs-27	377	3	,	,	PUNCT
asodahs-27	377	4	patel	patel	PROPN
asodahs-27	377	5	v	v	PROPN
asodahs-27	377	6	,	,	PUNCT
asodahs-27	377	7	jain	jain	PROPN
asodahs-27	377	8	dk	dk	PROPN
asodahs-27	377	9	,	,	PUNCT
asodahs-27	377	10	dewangan	dewangan	PROPN
asodahs-27	377	11	pk	pk	PROPN
asodahs-27	377	12	,	,	PUNCT
asodahs-27	377	13	sharma	sharma	PROPN
asodahs-27	377	14	pc	pc	PROPN
asodahs-27	377	15	,	,	PUNCT
asodahs-27	377	16	veerasamy	veerasamy	ADJ
asodahs-27	377	17	r	r	NOUN
asodahs-27	377	18	,	,	PUNCT
asodahs-27	377	19	gupta	gupta	PROPN
asodahs-27	377	20	ak	ak	PROPN
asodahs-27	377	21	,	,	PUNCT
asodahs-27	377	22	dangi	dangi	PROPN
asodahs-27	377	23	js	js	PROPN
asodahs-27	377	24	.	.	PUNCT
asodahs-27	378	1	structure	structure	NOUN
asodahs-27	378	2	-	-	PUNCT
asodahs-27	378	3	activity	activity	NOUN
asodahs-27	378	4	relationships	relationship	NOUN
asodahs-27	378	5	among	among	ADP
asodahs-27	378	6	novel	novel	NOUN
asodahs-27	378	7	1	1	NUM
asodahs-27	378	8	,	,	PUNCT
asodahs-27	378	9	3	3	NUM
asodahs-27	378	10	,	,	PUNCT
asodahs-27	378	11	4	4	NUM
asodahs-27	378	12	-	-	PUNCT
asodahs-27	378	13	oxadiazole	oxadiazole	NOUN
asodahs-27	378	14	analogues	analogue	NOUN
asodahs-27	378	15	for	for	ADP
asodahs-27	378	16	their	their	PRON
asodahs-27	378	17	anti	anti	ADJ
asodahs-27	378	18	-	-	ADJ
asodahs-27	378	19	inflammatory	inflammatory	ADJ
asodahs-27	378	20	activity	activity	NOUN
asodahs-27	378	21	.	.	PUNCT
asodahs-27	379	1	current	current	ADJ
asodahs-27	379	2	research	research	NOUN
asodahs-27	379	3	in	in	ADP
asodahs-27	379	4	pharmaceutical	pharmaceutical	ADJ
asodahs-27	379	5	sciences	science	NOUN
asodahs-27	379	6	.	.	PUNCT
asodahs-27	379	7	2012	2012	NUM
asodahs-27	379	8	;	;	PUNCT
asodahs-27	379	9	03:142	03:142	PROPN
asodahs-27	379	10	-	-	PUNCT
asodahs-27	379	11	148	148	NUM
asodahs-27	379	12	.	.	PUNCT
asodahs-27	380	1	14	14	NUM
asodahs-27	380	2	.	.	PUNCT
asodahs-27	381	1	ghofrani	ghofrani	PROPN
asodahs-27	381	2	ha	ha	INTJ
asodahs-27	381	3	,	,	PUNCT
asodahs-27	381	4	osterloh	osterloh	PROPN
asodahs-27	381	5	ih	ih	X
asodahs-27	381	6	,	,	PUNCT
asodahs-27	381	7	grimminger	grimminger	PROPN
asodahs-27	381	8	f.	f.	PROPN
asodahs-27	381	9	sildenafil	sildenafil	PROPN
asodahs-27	381	10	:	:	PUNCT
asodahs-27	381	11	from	from	ADP
asodahs-27	381	12	angina	angina	NOUN
asodahs-27	381	13	to	to	PART
asodahs-27	381	14	erectile	erectile	VERB
asodahs-27	381	15	dysfunction	dysfunction	NOUN
asodahs-27	381	16	to	to	ADP
asodahs-27	381	17	pulmonary	pulmonary	ADJ
asodahs-27	381	18	hypertension	hypertension	NOUN
asodahs-27	381	19	and	and	CCONJ
asodahs-27	381	20	beyond	beyond	ADP
asodahs-27	381	21	.	.	PUNCT
asodahs-27	382	1	nature	nature	NOUN
asodahs-27	382	2	reviews	review	VERB
asodahs-27	382	3	drug	drug	NOUN
asodahs-27	382	4	discovery	discovery	NOUN
asodahs-27	382	5	.	.	PUNCT
asodahs-27	383	1	2006	2006	NUM
asodahs-27	383	2	;	;	PUNCT
asodahs-27	383	3	5(8):689	5(8):689	NUM
asodahs-27	383	4	-	-	SYM
asodahs-27	383	5	702	702	NUM
asodahs-27	383	6	.	.	PUNCT
asodahs-27	384	1	https://doi.org/10.1038/nrd2030	https://doi.org/10.1038/nrd2030	PROPN
asodahs-27	384	2	https://doi.org/10.3233/mgc-180748	https://doi.org/10.3233/mgc-180748	NOUN
asodahs-27	384	3	https://doi.org/10.3322/caac.21492	https://doi.org/10.3322/caac.21492	PRON
asodahs-27	384	4	https://doi.org/10.1016/j.cbi.2006.12.006	https://doi.org/10.1016/j.cbi.2006.12.006	PROPN
asodahs-27	384	5	https://doi.org/10.1021/jm9704098	https://doi.org/10.1021/jm9704098	PROPN
asodahs-27	384	6	https://doi.org/10.1016/j.tips.2019.06.004	https://doi.org/10.1016/j.tips.2019.06.004	X
asodahs-27	384	7	https://doi.org/10.3233/mgc-180748	https://doi.org/10.3233/mgc-180748	NOUN
asodahs-27	385	1	https://doi.org/10.1038/s41587-019-0224-x	https://doi.org/10.1038/s41587-019-0224-x	PROPN
asodahs-27	385	2	https://doi.org/10.1126/science.287.5460.1960	https://doi.org/10.1126/science.287.5460.1960	PROPN
asodahs-27	386	1	https://doi.org/10.1093/bib/bbv066	https://doi.org/10.1093/bib/bbv066	PROPN
asodahs-27	386	2	https://doi.org/10.1146/annurev-pharmtox-010715-103440	https://doi.org/10.1146/annurev-pharmtox-010715-103440	INTJ
asodahs-27	386	3	https://doi.org/10.1146/annurev-pharmtox-010715-103440	https://doi.org/10.1146/annurev-pharmtox-010715-103440	INTJ
asodahs-27	386	4	https://doi.org/10.1038/nchembio.118	https://doi.org/10.1038/nchembio.118	X
asodahs-27	386	5	https://doi.org/10.1093/bioinformatics/btn162	https://doi.org/10.1093/bioinformatics/btn162	PROPN
asodahs-27	386	6	https://doi.org/10.1038/nrd2030	https://doi.org/10.1038/nrd2030	PROPN
asodahs-27	386	7	ahirwar	ahirwar	PROPN
asodahs-27	386	8	et	et	PROPN
asodahs-27	386	9	al	al	PROPN
asodahs-27	386	10	asian	asian	PROPN
asodahs-27	386	11	journal	journal	PROPN
asodahs-27	386	12	of	of	ADP
asodahs-27	386	13	dental	dental	ADJ
asodahs-27	386	14	and	and	CCONJ
asodahs-27	386	15	health	health	NOUN
asodahs-27	386	16	sciences	science	NOUN
asodahs-27	386	17	.	.	PUNCT
asodahs-27	386	18	2022	2022	NUM
asodahs-27	386	19	;	;	PUNCT
asodahs-27	386	20	2(4):59	2(4):59	NUM
asodahs-27	386	21	-	-	SYM
asodahs-27	386	22	63	63	NUM
asodahs-27	387	1	[	[	X
asodahs-27	387	2	63	63	NUM
asodahs-27	387	3	]	]	PUNCT
asodahs-27	387	4	ajdhs.com	ajdhs.com	X
asodahs-27	387	5	15	15	NUM
asodahs-27	387	6	.	.	PUNCT
asodahs-27	388	1	takarabe	takarabe	PROPN
asodahs-27	388	2	m	m	PROPN
asodahs-27	388	3	,	,	PUNCT
asodahs-27	388	4	kotera	kotera	PROPN
asodahs-27	388	5	m	m	PROPN
asodahs-27	388	6	,	,	PUNCT
asodahs-27	388	7	nishimura	nishimura	PROPN
asodahs-27	388	8	y	y	PROPN
asodahs-27	388	9	,	,	PUNCT
asodahs-27	388	10	goto	goto	NOUN
asodahs-27	388	11	s	s	NOUN
asodahs-27	388	12	,	,	PUNCT
asodahs-27	388	13	yamanishi	yamanishi	NOUN
asodahs-27	388	14	y.	y.	PROPN
asodahs-27	388	15	drug	drug	PROPN
asodahs-27	388	16	target	target	NOUN
asodahs-27	388	17	prediction	prediction	NOUN
asodahs-27	388	18	using	use	VERB
asodahs-27	388	19	adverse	adverse	ADJ
asodahs-27	388	20	event	event	NOUN
asodahs-27	388	21	report	report	NOUN
asodahs-27	388	22	systems	system	NOUN
asodahs-27	388	23	:	:	PUNCT
asodahs-27	388	24	a	a	DET
asodahs-27	388	25	pharmacogenomic	pharmacogenomic	ADJ
asodahs-27	388	26	approach	approach	NOUN
asodahs-27	388	27	.	.	PUNCT
asodahs-27	389	1	bioinformatics	bioinformatic	NOUN
asodahs-27	389	2	.	.	PUNCT
asodahs-27	390	1	2012	2012	NUM
asodahs-27	390	2	;	;	PUNCT
asodahs-27	390	3	28(18):i611i618	28(18):i611i618	NUM
asodahs-27	390	4	.	.	PUNCT
asodahs-27	391	1	https://doi.org/10.1093/bioinformatics/bts413	https://doi.org/10.1093/bioinformatics/bts413	PROPN
asodahs-27	391	2	16	16	NUM
asodahs-27	391	3	.	.	PUNCT
asodahs-27	392	1	campillos	campillos	PROPN
asodahs-27	392	2	m	m	PROPN
asodahs-27	392	3	,	,	PUNCT
asodahs-27	392	4	kuhn	kuhn	PROPN
asodahs-27	392	5	m	m	PROPN
asodahs-27	392	6	,	,	PUNCT
asodahs-27	392	7	gavin	gavin	PROPN
asodahs-27	392	8	ac	ac	PROPN
asodahs-27	392	9	,	,	PUNCT
asodahs-27	392	10	jensen	jensen	PROPN
asodahs-27	392	11	lj	lj	PROPN
asodahs-27	392	12	,	,	PUNCT
asodahs-27	392	13	bork	bork	PROPN
asodahs-27	392	14	p.	p.	NOUN
asodahs-27	392	15	drug	drug	NOUN
asodahs-27	392	16	target	target	NOUN
asodahs-27	392	17	identification	identification	NOUN
asodahs-27	392	18	using	use	VERB
asodahs-27	392	19	side	side	NOUN
asodahs-27	392	20	-	-	PUNCT
asodahs-27	392	21	effect	effect	NOUN
asodahs-27	392	22	similarity	similarity	NOUN
asodahs-27	392	23	.	.	PUNCT
asodahs-27	393	1	science	science	NOUN
asodahs-27	393	2	.	.	PUNCT
asodahs-27	393	3	2008	2008	NUM
asodahs-27	393	4	;	;	PUNCT
asodahs-27	393	5	321(5886):263	321(5886):263	NUM
asodahs-27	393	6	-	-	SYM
asodahs-27	393	7	266	266	NUM
asodahs-27	393	8	.	.	PUNCT
asodahs-27	393	9	https://doi.org/10.1126/science.1158140	https://doi.org/10.1126/science.1158140	NOUN
asodahs-27	393	10	17	17	NUM
asodahs-27	393	11	.	.	PUNCT
asodahs-27	394	1	klipp	klipp	PROPN
asodahs-27	394	2	e	e	X
asodahs-27	394	3	,	,	PUNCT
asodahs-27	394	4	wade	wade	PROPN
asodahs-27	394	5	rc	rc	PROPN
asodahs-27	394	6	,	,	PUNCT
asodahs-27	394	7	kummer	kummer	PROPN
asodahs-27	394	8	u.	u.	PROPN
asodahs-27	394	9	biochemical	biochemical	ADJ
asodahs-27	394	10	network	network	NOUN
asodahs-27	394	11	-	-	PUNCT
asodahs-27	394	12	based	base	VERB
asodahs-27	394	13	drugtarget	drugtarget	NOUN
asodahs-27	394	14	prediction	prediction	NOUN
asodahs-27	394	15	.	.	PUNCT
asodahs-27	395	1	current	current	ADJ
asodahs-27	395	2	opinion	opinion	NOUN
asodahs-27	395	3	in	in	ADP
asodahs-27	395	4	biotechnology	biotechnology	NOUN
asodahs-27	395	5	.	.	PUNCT
asodahs-27	396	1	2010	2010	NUM
asodahs-27	396	2	;	;	PUNCT
asodahs-27	396	3	21(4):511	21(4):511	NUM
asodahs-27	396	4	-	-	SYM
asodahs-27	396	5	516	516	NUM
asodahs-27	396	6	.	.	PUNCT
asodahs-27	397	1	https://doi.org/10.1016/j.copbio.2010.05.004	https://doi.org/10.1016/j.copbio.2010.05.004	VERB
asodahs-27	397	2	18	18	NUM
asodahs-27	397	3	.	.	PUNCT
asodahs-27	398	1	srivastava	srivastava	PROPN
asodahs-27	398	2	n	n	PROPN
asodahs-27	398	3	,	,	PUNCT
asodahs-27	398	4	hinton	hinton	PROPN
asodahs-27	398	5	g	g	PROPN
asodahs-27	398	6	,	,	PUNCT
asodahs-27	398	7	krizhevsky	krizhevsky	PROPN
asodahs-27	398	8	a	a	NOUN
asodahs-27	398	9	,	,	PUNCT
asodahs-27	398	10	sutskever	sutskever	VERB
asodahs-27	398	11	i	i	PROPN
asodahs-27	398	12	,	,	PUNCT
asodahs-27	398	13	salakhutdinov	salakhutdinov	PROPN
asodahs-27	398	14	r.	r.	PROPN
asodahs-27	398	15	dropout	dropout	PROPN
asodahs-27	398	16	:	:	PUNCT
asodahs-27	398	17	a	a	DET
asodahs-27	398	18	simple	simple	ADJ
asodahs-27	398	19	way	way	NOUN
asodahs-27	398	20	to	to	PART
asodahs-27	398	21	prevent	prevent	VERB
asodahs-27	398	22	neural	neural	ADJ
asodahs-27	398	23	networks	network	NOUN
asodahs-27	398	24	from	from	ADP
asodahs-27	398	25	overfitting	overfitte	VERB
asodahs-27	398	26	.	.	PUNCT
asodahs-27	399	1	the	the	DET
asodahs-27	399	2	journal	journal	NOUN
asodahs-27	399	3	of	of	ADP
asodahs-27	399	4	machine	machine	NOUN
asodahs-27	399	5	learning	learn	VERB
asodahs-27	399	6	research	research	NOUN
asodahs-27	399	7	.	.	PUNCT
asodahs-27	400	1	2014	2014	NUM
asodahs-27	400	2	;	;	PUNCT
asodahs-27	400	3	15(1):1929	15(1):1929	NUM
asodahs-27	400	4	-	-	SYM
asodahs-27	400	5	1958	1958	NUM
asodahs-27	400	6	.	.	PUNCT
asodahs-27	401	1	19	19	NUM
asodahs-27	401	2	.	.	PUNCT
asodahs-27	401	3	li	li	PROPN
asodahs-27	401	4	x	x	PROPN
asodahs-27	401	5	,	,	PUNCT
asodahs-27	401	6	chen	chen	PROPN
asodahs-27	401	7	h.	h.	PROPN
asodahs-27	401	8	recommendation	recommendation	PROPN
asodahs-27	401	9	as	as	ADP
asodahs-27	401	10	link	link	NOUN
asodahs-27	401	11	prediction	prediction	NOUN
asodahs-27	401	12	in	in	ADP
asodahs-27	401	13	bipartite	bipartite	PROPN
asodahs-27	401	14	graphs	graph	NOUN
asodahs-27	401	15	:	:	PUNCT
asodahs-27	401	16	a	a	DET
asodahs-27	401	17	graph	graph	NOUN
asodahs-27	401	18	kernel	kernel	NOUN
asodahs-27	401	19	-	-	PUNCT
asodahs-27	401	20	based	base	VERB
asodahs-27	401	21	machine	machine	NOUN
asodahs-27	401	22	learning	learning	NOUN
asodahs-27	401	23	approach	approach	NOUN
asodahs-27	401	24	.	.	PUNCT
asodahs-27	402	1	decision	decision	NOUN
asodahs-27	402	2	support	support	NOUN
asodahs-27	402	3	systems	system	NOUN
asodahs-27	402	4	.	.	PUNCT
asodahs-27	403	1	2013	2013	NUM
asodahs-27	403	2	;	;	PUNCT
asodahs-27	403	3	54(2):880	54(2):880	NUM
asodahs-27	403	4	-	-	PUNCT
asodahs-27	403	5	890	890	NUM
asodahs-27	403	6	.	.	PUNCT
asodahs-27	404	1	https://doi.org/10.1016/j.dss.2012.09.019	https://doi.org/10.1016/j.dss.2012.09.019	PRON
asodahs-27	404	2	20	20	NUM
asodahs-27	404	3	.	.	PUNCT
asodahs-27	404	4	yıldırım	yıldırım	PROPN
asodahs-27	404	5	ma	ma	PROPN
asodahs-27	404	6	,	,	PUNCT
asodahs-27	404	7	goh	goh	PROPN
asodahs-27	404	8	ki	ki	PROPN
asodahs-27	404	9	,	,	PUNCT
asodahs-27	404	10	cusick	cusick	PROPN
asodahs-27	404	11	me	i	PRON
asodahs-27	404	12	,	,	PUNCT
asodahs-27	404	13	barabási	barabási	PROPN
asodahs-27	404	14	al	al	PROPN
asodahs-27	404	15	,	,	PUNCT
asodahs-27	404	16	vidal	vidal	PROPN
asodahs-27	404	17	m.	m.	NOUN
asodahs-27	404	18	drug	drug	NOUN
asodahs-27	404	19	-	-	PUNCT
asodahs-27	404	20	target	target	NOUN
asodahs-27	404	21	network	network	NOUN
asodahs-27	404	22	.	.	PUNCT
asodahs-27	405	1	nature	nature	NOUN
asodahs-27	405	2	biotechnology	biotechnology	NOUN
asodahs-27	405	3	.	.	PUNCT
asodahs-27	406	1	2007	2007	NUM
asodahs-27	406	2	;	;	PUNCT
asodahs-27	406	3	25(10):1119	25(10):1119	NUM
asodahs-27	406	4	-	-	SYM
asodahs-27	406	5	1126	1126	NUM
asodahs-27	406	6	.	.	PUNCT
asodahs-27	407	1	https://doi.org/10.1038/nbt1338	https://doi.org/10.1038/nbt1338	NOUN
asodahs-27	407	2	21	21	NUM
asodahs-27	407	3	.	.	PUNCT
asodahs-27	408	1	mayr	mayr	PROPN
asodahs-27	408	2	a	a	PRON
asodahs-27	408	3	,	,	PUNCT
asodahs-27	408	4	klambauer	klambauer	NOUN
asodahs-27	408	5	g	g	PROPN
asodahs-27	408	6	,	,	PUNCT
asodahs-27	408	7	unterthiner	unterthiner	PROPN
asodahs-27	408	8	t	t	PROPN
asodahs-27	408	9	,	,	PUNCT
asodahs-27	408	10	steijaert	steijaert	ADJ
asodahs-27	408	11	m	m	PROPN
asodahs-27	408	12	,	,	PUNCT
asodahs-27	408	13	wegner	wegner	PROPN
asodahs-27	408	14	jk	jk	PROPN
asodahs-27	408	15	,	,	PUNCT
asodahs-27	408	16	ceulemans	ceuleman	VERB
asodahs-27	408	17	h	h	NOUN
asodahs-27	408	18	,	,	PUNCT
asodahs-27	408	19	hochreiter	hochreiter	PROPN
asodahs-27	408	20	s.	s.	PROPN
asodahs-27	408	21	large	large	ADJ
asodahs-27	408	22	-	-	PUNCT
asodahs-27	408	23	scale	scale	NOUN
asodahs-27	408	24	comparison	comparison	NOUN
asodahs-27	408	25	of	of	ADP
asodahs-27	408	26	machine	machine	NOUN
asodahs-27	408	27	learning	learning	NOUN
asodahs-27	408	28	methods	method	NOUN
asodahs-27	408	29	for	for	ADP
asodahs-27	408	30	drug	drug	NOUN
asodahs-27	408	31	target	target	NOUN
asodahs-27	408	32	prediction	prediction	NOUN
asodahs-27	408	33	on	on	ADP
asodahs-27	408	34	chembl	chembl	NOUN
asodahs-27	408	35	.	.	PUNCT
asodahs-27	409	1	chemical	chemical	NOUN
asodahs-27	409	2	science	science	NOUN
asodahs-27	409	3	.	.	PUNCT
asodahs-27	410	1	2018	2018	NUM
asodahs-27	410	2	;	;	PUNCT
asodahs-27	410	3	9(24):5441	9(24):5441	NUM
asodahs-27	410	4	-	-	SYM
asodahs-27	410	5	5451	5451	NUM
asodahs-27	410	6	.	.	PUNCT
asodahs-27	411	1	https://doi.org/10.1039/c8sc00148k	https://doi.org/10.1039/c8sc00148k	PROPN
asodahs-27	411	2	22	22	NUM
asodahs-27	411	3	.	.	PUNCT
asodahs-27	412	1	mendenhall	mendenhall	PROPN
asodahs-27	412	2	j	j	PROPN
asodahs-27	412	3	,	,	PUNCT
asodahs-27	412	4	meiler	meiler	NOUN
asodahs-27	412	5	j.	j.	PROPN
asodahs-27	412	6	improving	improve	VERB
asodahs-27	412	7	quantitative	quantitative	ADJ
asodahs-27	412	8	structure	structure	NOUN
asodahs-27	412	9	-	-	PUNCT
asodahs-27	412	10	activity	activity	NOUN
asodahs-27	412	11	relationship	relationship	NOUN
asodahs-27	412	12	models	model	NOUN
asodahs-27	412	13	using	use	VERB
asodahs-27	412	14	artificial	artificial	ADJ
asodahs-27	412	15	neural	neural	ADJ
asodahs-27	412	16	networks	network	NOUN
asodahs-27	412	17	trained	train	VERB
asodahs-27	412	18	with	with	ADP
asodahs-27	412	19	dropout	dropout	NOUN
asodahs-27	412	20	.	.	PUNCT
asodahs-27	413	1	journal	journal	NOUN
asodahs-27	413	2	of	of	ADP
asodahs-27	413	3	computer	computer	NOUN
asodahs-27	413	4	-	-	PUNCT
asodahs-27	413	5	aided	aid	VERB
asodahs-27	413	6	molecular	molecular	ADJ
asodahs-27	413	7	design	design	NOUN
asodahs-27	413	8	.	.	PUNCT
asodahs-27	414	1	2016	2016	NUM
asodahs-27	414	2	;	;	PUNCT
asodahs-27	414	3	30(2):177	30(2):177	NUM
asodahs-27	414	4	-	-	SYM
asodahs-27	414	5	189	189	NUM
asodahs-27	414	6	.	.	PUNCT
asodahs-27	415	1	https://doi.org/10.1007/s10822-016-9895-2	https://doi.org/10.1007/s10822-016-9895-2	PROPN
asodahs-27	415	2	23	23	NUM
asodahs-27	415	3	.	.	PUNCT
asodahs-27	416	1	hansch	hansch	PROPN
asodahs-27	416	2	c	c	PROPN
asodahs-27	416	3	,	,	PUNCT
asodahs-27	416	4	fujita	fujita	PROPN
asodahs-27	416	5	t.	t.	PROPN
asodahs-27	416	6	additions	addition	NOUN
asodahs-27	416	7	and	and	CCONJ
asodahs-27	416	8	corrections	correction	NOUN
asodahs-27	416	9	-	-	PUNCT
asodahs-27	416	10	ρ	ρ	NUM
asodahs-27	416	11	-	-	PUNCT
asodahs-27	416	12	ς	ς	NOUN
asodahs-27	416	13	-	-	PUNCT
asodahs-27	416	14	π	π	NOUN
asodahs-27	416	15	analysis	analysis	NOUN
asodahs-27	416	16	.	.	PUNCT
asodahs-27	417	1	a	a	DET
asodahs-27	417	2	method	method	NOUN
asodahs-27	417	3	for	for	ADP
asodahs-27	417	4	the	the	DET
asodahs-27	417	5	correlation	correlation	NOUN
asodahs-27	417	6	of	of	ADP
asodahs-27	417	7	biological	biological	ADJ
asodahs-27	417	8	activity	activity	NOUN
asodahs-27	417	9	and	and	CCONJ
asodahs-27	417	10	chemical	chemical	NOUN
asodahs-27	417	11	structure	structure	NOUN
asodahs-27	417	12	.	.	PUNCT
asodahs-27	418	1	journal	journal	NOUN
asodahs-27	418	2	of	of	ADP
asodahs-27	418	3	the	the	DET
asodahs-27	418	4	american	american	PROPN
asodahs-27	418	5	chemical	chemical	PROPN
asodahs-27	418	6	society	society	NOUN
asodahs-27	418	7	.	.	PUNCT
asodahs-27	419	1	1964	1964	NUM
asodahs-27	419	2	;	;	PUNCT
asodahs-27	419	3	86(24):5710	86(24):5710	NUM
asodahs-27	419	4	-	-	SYM
asodahs-27	419	5	5710	5710	NUM
asodahs-27	419	6	.	.	PUNCT
asodahs-27	420	1	https://doi.org/10.1021/ja01078a623	https://doi.org/10.1021/ja01078a623	PROPN
asodahs-27	420	2	24	24	NUM
asodahs-27	420	3	.	.	PUNCT
asodahs-27	421	1	cramer	cramer	PROPN
asodahs-27	421	2	rd	rd	PROPN
asodahs-27	421	3	,	,	PUNCT
asodahs-27	421	4	patterson	patterson	PROPN
asodahs-27	421	5	de	de	PROPN
asodahs-27	421	6	,	,	PUNCT
asodahs-27	421	7	bunce	bunce	PROPN
asodahs-27	421	8	jd	jd	PROPN
asodahs-27	421	9	.	.	PROPN
asodahs-27	421	10	comparative	comparative	ADJ
asodahs-27	421	11	molecular	molecular	ADJ
asodahs-27	421	12	field	field	NOUN
asodahs-27	421	13	analysis	analysis	NOUN
asodahs-27	421	14	(	(	PUNCT
asodahs-27	421	15	comfa	comfa	NOUN
asodahs-27	421	16	)	)	PUNCT
asodahs-27	421	17	.	.	PUNCT
asodahs-27	422	1	1	1	X
asodahs-27	422	2	.	.	X
asodahs-27	422	3	effect	effect	NOUN
asodahs-27	422	4	of	of	ADP
asodahs-27	422	5	shape	shape	NOUN
asodahs-27	422	6	on	on	ADP
asodahs-27	422	7	binding	bind	VERB
asodahs-27	422	8	of	of	ADP
asodahs-27	422	9	steroids	steroid	NOUN
asodahs-27	422	10	to	to	ADP
asodahs-27	422	11	carrier	carrier	NOUN
asodahs-27	422	12	proteins	protein	NOUN
asodahs-27	422	13	.	.	PUNCT
asodahs-27	423	1	journal	journal	NOUN
asodahs-27	423	2	of	of	ADP
asodahs-27	423	3	the	the	DET
asodahs-27	423	4	american	american	PROPN
asodahs-27	423	5	chemical	chemical	PROPN
asodahs-27	423	6	society	society	NOUN
asodahs-27	423	7	.	.	PUNCT
asodahs-27	424	1	1998	1998	NUM
asodahs-27	424	2	;	;	PUNCT
asodahs-27	424	3	110(18):5959	110(18):5959	X
asodahs-27	424	4	-	-	SYM
asodahs-27	424	5	5967	5967	NUM
asodahs-27	424	6	.	.	PUNCT
asodahs-27	425	1	https://doi.org/10.1021/ja00226a005	https://doi.org/10.1021/ja00226a005	ADV
asodahs-27	425	2	25	25	NUM
asodahs-27	425	3	.	.	PUNCT
asodahs-27	426	1	klebe	klebe	VERB
asodahs-27	426	2	g	g	PROPN
asodahs-27	426	3	,	,	PUNCT
asodahs-27	426	4	abraham	abraham	PROPN
asodahs-27	426	5	u	u	PROPN
asodahs-27	426	6	,	,	PUNCT
asodahs-27	426	7	mietzner	mietzner	ADJ
asodahs-27	426	8	t.	t.	PROPN
asodahs-27	426	9	molecular	molecular	ADJ
asodahs-27	426	10	similarity	similarity	NOUN
asodahs-27	426	11	indices	indice	VERB
asodahs-27	426	12	in	in	ADP
asodahs-27	426	13	a	a	DET
asodahs-27	426	14	comparative	comparative	ADJ
asodahs-27	426	15	analysis	analysis	NOUN
asodahs-27	426	16	(	(	PUNCT
asodahs-27	426	17	comsia	comsia	NOUN
asodahs-27	426	18	)	)	PUNCT
asodahs-27	426	19	of	of	ADP
asodahs-27	426	20	drug	drug	NOUN
asodahs-27	426	21	molecules	molecule	NOUN
asodahs-27	426	22	to	to	PART
asodahs-27	426	23	correlate	correlate	VERB
asodahs-27	426	24	and	and	CCONJ
asodahs-27	426	25	predict	predict	VERB
asodahs-27	426	26	their	their	PRON
asodahs-27	426	27	biological	biological	ADJ
asodahs-27	426	28	activity	activity	NOUN
asodahs-27	426	29	.	.	PUNCT
asodahs-27	427	1	journal	journal	NOUN
asodahs-27	427	2	of	of	ADP
asodahs-27	427	3	medicinal	medicinal	ADJ
asodahs-27	427	4	chemistry	chemistry	NOUN
asodahs-27	427	5	.	.	PUNCT
asodahs-27	428	1	1994	1994	NUM
asodahs-27	428	2	;	;	PUNCT
asodahs-27	428	3	37(24):4130	37(24):4130	NUM
asodahs-27	428	4	-	-	SYM
asodahs-27	428	5	4146	4146	NUM
asodahs-27	428	6	.	.	PUNCT
asodahs-27	429	1	https://doi.org/10.1021/jm00050a010	https://doi.org/10.1021/jm00050a010	NOUN
asodahs-27	429	2	26	26	NUM
asodahs-27	429	3	.	.	PUNCT
asodahs-27	430	1	alomari	alomari	PROPN
asodahs-27	430	2	fy	fy	PROPN
asodahs-27	430	3	,	,	PUNCT
asodahs-27	430	4	sharfalddin	sharfalddin	VERB
asodahs-27	430	5	aa	aa	NOUN
asodahs-27	430	6	,	,	PUNCT
asodahs-27	430	7	abdellattif	abdellattif	PROPN
asodahs-27	430	8	mh	mh	PROPN
asodahs-27	430	9	,	,	PUNCT
asodahs-27	430	10	domyati	domyati	NOUN
asodahs-27	430	11	d	d	PROPN
asodahs-27	430	12	,	,	PUNCT
asodahs-27	430	13	basaleh	basaleh	VERB
asodahs-27	430	14	as	as	ADP
asodahs-27	430	15	,	,	PUNCT
asodahs-27	430	16	hussien	hussien	PROPN
asodahs-27	430	17	ma	ma	PROPN
asodahs-27	430	18	.	.	PROPN
asodahs-27	430	19	qsar	qsar	PROPN
asodahs-27	430	20	modeling	modeling	NOUN
asodahs-27	430	21	,	,	PUNCT
asodahs-27	430	22	molecular	molecular	ADJ
asodahs-27	430	23	docking	docking	NOUN
asodahs-27	430	24	and	and	CCONJ
asodahs-27	430	25	cytotoxic	cytotoxic	ADJ
asodahs-27	430	26	evaluation	evaluation	NOUN
asodahs-27	430	27	for	for	ADP
asodahs-27	430	28	novel	novel	ADJ
asodahs-27	430	29	oxidovanadium	oxidovanadium	NOUN
asodahs-27	430	30	(	(	PUNCT
asodahs-27	430	31	iv	iv	NOUN
asodahs-27	430	32	)	)	PUNCT
asodahs-27	430	33	complexes	complex	NOUN
asodahs-27	430	34	as	as	ADP
asodahs-27	430	35	colon	colon	NOUN
asodahs-27	430	36	anticancer	anticancer	NOUN
asodahs-27	430	37	agents	agent	NOUN
asodahs-27	430	38	.	.	PUNCT
asodahs-27	431	1	molecules	molecule	NOUN
asodahs-27	431	2	.	.	PUNCT
asodahs-27	432	1	2022	2022	NUM
asodahs-27	432	2	;	;	PUNCT
asodahs-27	432	3	27(3):649	27(3):649	X
asodahs-27	432	4	.	.	PUNCT
asodahs-27	433	1	https://doi.org/10.3390/molecules27030649	https://doi.org/10.3390/molecules27030649	NOUN
asodahs-27	433	2	27	27	NUM
asodahs-27	433	3	.	.	PUNCT
asodahs-27	434	1	adhikari	adhikari	PROPN
asodahs-27	434	2	n	n	PROPN
asodahs-27	434	3	,	,	PUNCT
asodahs-27	434	4	amin	amin	PROPN
asodahs-27	434	5	sa	sa	PROPN
asodahs-27	434	6	,	,	PUNCT
asodahs-27	434	7	trivedi	trivedi	PROPN
asodahs-27	434	8	p	p	PROPN
asodahs-27	434	9	,	,	PUNCT
asodahs-27	434	10	jha	jha	PROPN
asodahs-27	434	11	t	t	PROPN
asodahs-27	434	12	,	,	PUNCT
asodahs-27	434	13	ghosh	ghosh	PROPN
asodahs-27	434	14	b.	b.	PROPN
asodahs-27	434	15	hdac3	hdac3	PROPN
asodahs-27	434	16	is	be	AUX
asodahs-27	434	17	a	a	DET
asodahs-27	434	18	potential	potential	ADJ
asodahs-27	434	19	validated	validate	VERB
asodahs-27	434	20	target	target	NOUN
asodahs-27	434	21	for	for	ADP
asodahs-27	434	22	cancer	cancer	NOUN
asodahs-27	434	23	:	:	PUNCT
asodahs-27	434	24	an	an	DET
asodahs-27	434	25	overview	overview	NOUN
asodahs-27	434	26	on	on	ADP
asodahs-27	434	27	the	the	DET
asodahs-27	434	28	benzamide	benzamide	NOUN
asodahs-27	434	29	-	-	PUNCT
asodahs-27	434	30	based	base	VERB
asodahs-27	434	31	selective	selective	ADJ
asodahs-27	434	32	hdac3	hdac3	NOUN
asodahs-27	434	33	inhibitors	inhibitor	NOUN
asodahs-27	434	34	through	through	ADP
asodahs-27	434	35	comparative	comparative	ADJ
asodahs-27	434	36	sar	sar	PROPN
asodahs-27	434	37	/	/	SYM
asodahs-27	434	38	qsar	qsar	NOUN
asodahs-27	434	39	/	/	SYM
asodahs-27	434	40	qaar	qaar	NOUN
asodahs-27	434	41	approaches	approach	NOUN
asodahs-27	434	42	.	.	PUNCT
asodahs-27	435	1	european	european	ADJ
asodahs-27	435	2	journal	journal	PROPN
asodahs-27	435	3	of	of	ADP
asodahs-27	435	4	medicinal	medicinal	ADJ
asodahs-27	435	5	chemistry	chemistry	NOUN
asodahs-27	435	6	.	.	PUNCT
asodahs-27	436	1	2018	2018	NUM
asodahs-27	436	2	;	;	PUNCT
asodahs-27	437	1	157:1127	157:1127	NUM
asodahs-27	437	2	-	-	SYM
asodahs-27	437	3	1142	1142	NUM
asodahs-27	437	4	.	.	PUNCT
asodahs-27	438	1	https://doi.org/10.1016/j.ejmech.2018.08.081	https://doi.org/10.1016/j.ejmech.2018.08.081	PRON
asodahs-27	438	2	28	28	NUM
asodahs-27	438	3	.	.	PUNCT
asodahs-27	439	1	singh	singh	PROPN
asodahs-27	439	2	a	a	PRON
asodahs-27	439	3	,	,	PUNCT
asodahs-27	439	4	patel	patel	PROPN
asodahs-27	439	5	vk	vk	PROPN
asodahs-27	439	6	,	,	PUNCT
asodahs-27	439	7	jain	jain	PROPN
asodahs-27	439	8	dk	dk	PROPN
asodahs-27	439	9	,	,	PUNCT
asodahs-27	439	10	sharma	sharma	PROPN
asodahs-27	439	11	pc	pc	PROPN
asodahs-27	439	12	,	,	PUNCT
asodahs-27	439	13	gupta	gupta	PROPN
asodahs-27	439	14	ak	ak	PROPN
asodahs-27	439	15	,	,	PUNCT
asodahs-27	439	16	sharma	sharma	PROPN
asodahs-27	439	17	ak	ak	PROPN
asodahs-27	439	18	,	,	PUNCT
asodahs-27	439	19	rajak	rajak	PROPN
asodahs-27	439	20	h.	h.	PROPN
asodahs-27	439	21	histone	histone	PROPN
asodahs-27	439	22	deacetylase	deacetylase	VERB
asodahs-27	439	23	inhibitors	inhibitor	NOUN
asodahs-27	439	24	:	:	PUNCT
asodahs-27	439	25	current	current	ADJ
asodahs-27	439	26	status	status	NOUN
asodahs-27	439	27	in	in	ADP
asodahs-27	439	28	treatment	treatment	NOUN
asodahs-27	439	29	of	of	ADP
asodahs-27	439	30	leukemia	leukemia	NOUN
asodahs-27	439	31	.	.	PUNCT
asodahs-27	440	1	current	current	ADJ
asodahs-27	440	2	research	research	NOUN
asodahs-27	440	3	in	in	ADP
asodahs-27	440	4	pharmaceutical	pharmaceutical	ADJ
asodahs-27	440	5	sciences	science	NOUN
asodahs-27	440	6	.	.	PUNCT
asodahs-27	441	1	2013	2013	NUM
asodahs-27	441	2	;	;	PUNCT
asodahs-27	441	3	03	03	NUM
asodahs-27	441	4	(	(	PUNCT
asodahs-27	441	5	04):102	04):102	NUM
asodahs-27	441	6	-	-	PUNCT
asodahs-27	441	7	107	107	NUM
asodahs-27	441	8	https://doi.org/10.1093/bioinformatics/bts413	https://doi.org/10.1093/bioinformatics/bts413	PROPN
asodahs-27	441	9	https://doi.org/10.1126/science.1158140	https://doi.org/10.1126/science.1158140	NOUN
asodahs-27	441	10	https://doi.org/10.1016/j.copbio.2010.05.004	https://doi.org/10.1016/j.copbio.2010.05.004	NOUN
asodahs-27	441	11	https://doi.org/10.1016/j.dss.2012.09.019	https://doi.org/10.1016/j.dss.2012.09.019	PRON
asodahs-27	441	12	https://doi.org/10.1038/nbt1338	https://doi.org/10.1038/nbt1338	NOUN
asodahs-27	441	13	https://doi.org/10.1039/c8sc00148k	https://doi.org/10.1039/c8sc00148k	X
asodahs-27	441	14	https://doi.org/10.1007/s10822-016-9895-2	https://doi.org/10.1007/s10822-016-9895-2	NUM
asodahs-27	441	15	https://doi.org/10.1021/ja01078a623	https://doi.org/10.1021/ja01078a623	PROPN
asodahs-27	442	1	https://doi.org/10.1021/ja00226a005	https://doi.org/10.1021/ja00226a005	PROPN
asodahs-27	442	2	https://doi.org/10.1021/jm00050a010	https://doi.org/10.1021/jm00050a010	PROPN
asodahs-27	442	3	https://doi.org/10.3390/molecules27030649	https://doi.org/10.3390/molecules27030649	NOUN
asodahs-27	442	4	https://doi.org/10.1016/j.ejmech.2018.08.081	https://doi.org/10.1016/j.ejmech.2018.08.081	PRON