id	sid	tid	token	lemma	pos
asodahs-29	1	1	dangi	dangi	INTJ
asodahs-29	1	2	et	et	PROPN
asodahs-29	1	3	al	al	PROPN
asodahs-29	1	4	asian	asian	PROPN
asodahs-29	1	5	journal	journal	PROPN
asodahs-29	1	6	of	of	ADP
asodahs-29	1	7	dental	dental	ADJ
asodahs-29	1	8	and	and	CCONJ
asodahs-29	1	9	health	health	NOUN
asodahs-29	1	10	sciences	science	NOUN
asodahs-29	1	11	.	.	PUNCT
asodahs-29	1	12	2022	2022	NUM
asodahs-29	1	13	;	;	PUNCT
asodahs-29	1	14	2(3):19	2(3):19	NUM
asodahs-29	1	15	-	-	SYM
asodahs-29	1	16	22	22	NUM
asodahs-29	2	1	[	[	X
asodahs-29	2	2	19	19	NUM
asodahs-29	2	3	]	]	PUNCT
asodahs-29	2	4	ajdhs.com	ajdhs.com	X
asodahs-29	2	5	available	available	ADJ
asodahs-29	2	6	online	online	ADV
asodahs-29	2	7	at	at	ADP
asodahs-29	2	8	ajdhs.com	ajdhs.com	X
asodahs-29	2	9	asian	asian	ADJ
asodahs-29	2	10	journal	journal	NOUN
asodahs-29	2	11	of	of	ADP
asodahs-29	2	12	dental	dental	ADJ
asodahs-29	2	13	and	and	CCONJ
asodahs-29	2	14	health	health	NOUN
asodahs-29	2	15	sciences	science	NOUN
asodahs-29	2	16	open	open	VERB
asodahs-29	2	17	access	access	NOUN
asodahs-29	2	18	to	to	ADP
asodahs-29	2	19	dental	dental	ADJ
asodahs-29	2	20	and	and	CCONJ
asodahs-29	2	21	health	health	NOUN
asodahs-29	2	22	research	research	NOUN
asodahs-29	2	23	copyright	copyright	NOUN
asodahs-29	2	24	©	©	ADP
asodahs-29	2	25	2022	2022	NUM
asodahs-29	2	26	the	the	DET
asodahs-29	2	27	author(s	author(s	NOUN
asodahs-29	2	28	):	):	PUNCT
asodahs-29	2	29	this	this	PRON
asodahs-29	2	30	is	be	AUX
asodahs-29	2	31	an	an	DET
asodahs-29	2	32	open	open	ADJ
asodahs-29	2	33	-	-	PUNCT
asodahs-29	2	34	access	access	NOUN
asodahs-29	2	35	article	article	NOUN
asodahs-29	2	36	distributed	distribute	VERB
asodahs-29	2	37	under	under	ADP
asodahs-29	2	38	the	the	DET
asodahs-29	2	39	terms	term	NOUN
asodahs-29	2	40	of	of	ADP
asodahs-29	2	41	the	the	DET
asodahs-29	2	42	cc	cc	PROPN
asodahs-29	2	43	by	by	ADP
asodahs-29	2	44	-	-	PUNCT
asodahs-29	2	45	nc	nc	PROPN
asodahs-29	2	46	4.0	4.0	NUM
asodahs-29	2	47	which	which	PRON
asodahs-29	2	48	permits	permit	VERB
asodahs-29	2	49	unrestricted	unrestricted	ADJ
asodahs-29	2	50	use	use	NOUN
asodahs-29	2	51	,	,	PUNCT
asodahs-29	2	52	distribution	distribution	NOUN
asodahs-29	2	53	,	,	PUNCT
asodahs-29	2	54	and	and	CCONJ
asodahs-29	2	55	reproduction	reproduction	NOUN
asodahs-29	2	56	in	in	ADP
asodahs-29	2	57	any	any	DET
asodahs-29	2	58	medium	medium	NOUN
asodahs-29	2	59	for	for	ADP
asodahs-29	2	60	non	non	ADJ
asodahs-29	2	61	-	-	ADJ
asodahs-29	2	62	commercial	commercial	ADJ
asodahs-29	2	63	use	use	NOUN
asodahs-29	2	64	provided	provide	VERB
asodahs-29	2	65	the	the	DET
asodahs-29	2	66	original	original	ADJ
asodahs-29	2	67	author	author	NOUN
asodahs-29	2	68	and	and	CCONJ
asodahs-29	2	69	source	source	NOUN
asodahs-29	2	70	are	be	AUX
asodahs-29	2	71	credited	credit	VERB
asodahs-29	2	72	development	development	NOUN
asodahs-29	2	73	and	and	CCONJ
asodahs-29	2	74	characterization	characterization	NOUN
asodahs-29	2	75	of	of	ADP
asodahs-29	2	76	tramadol	tramadol	NOUN
asodahs-29	2	77	hydrochloride	hydrochloride	NOUN
asodahs-29	2	78	rectal	rectal	ADJ
asodahs-29	2	79	suppository	suppository	PROPN
asodahs-29	2	80	nanci	nanci	PROPN
asodahs-29	2	81	dangi	dangi	PROPN
asodahs-29	2	82	,	,	PUNCT
asodahs-29	2	83	sunil	sunil	PROPN
asodahs-29	2	84	k.	k.	PROPN
asodahs-29	2	85	jain	jain	PROPN
asodahs-29	2	86	,	,	PUNCT
asodahs-29	2	87	vivek	vivek	PROPN
asodahs-29	2	88	jain	jain	PROPN
asodahs-29	2	89	,	,	PUNCT
asodahs-29	2	90	rupesh	rupesh	PROPN
asodahs-29	2	91	k.	k.	PROPN
asodahs-29	2	92	jain	jain	PROPN
asodahs-29	2	93	,	,	PUNCT
asodahs-29	2	94	pushpendra	pushpendra	PROPN
asodahs-29	2	95	kumar	kumar	PROPN
asodahs-29	2	96	khangar	khangar	PROPN
asodahs-29	2	97	*	*	PROPN
asodahs-29	2	98	adina	adina	PROPN
asodahs-29	2	99	institute	institute	PROPN
asodahs-29	2	100	of	of	ADP
asodahs-29	2	101	pharmaceutical	pharmaceutical	PROPN
asodahs-29	2	102	sciences	science	NOUN
asodahs-29	2	103	,	,	PUNCT
asodahs-29	2	104	nh86	nh86	PROPN
asodahs-29	2	105	lahadara	lahadara	PROPN
asodahs-29	2	106	naka	naka	PROPN
asodahs-29	2	107	bhopal	bhopal	PROPN
asodahs-29	2	108	road	road	NOUN
asodahs-29	2	109	sagar	sagar	PROPN
asodahs-29	2	110	,	,	PUNCT
asodahs-29	2	111	m.p	m.p	PROPN
asodahs-29	2	112	.	.	PROPN
asodahs-29	2	113	,	,	PUNCT
asodahs-29	2	114	india	india	PROPN
asodahs-29	2	115	article	article	PROPN
asodahs-29	2	116	info	info	NOUN
asodahs-29	2	117	:	:	PUNCT
asodahs-29	3	1	_	_	PUNCT
asodahs-29	4	1	_	_	PUNCT
asodahs-29	5	1	_	_	PUNCT
asodahs-29	6	1	_	_	PUNCT
asodahs-29	7	1	_	_	PUNCT
asodahs-29	8	1	_	_	PUNCT
asodahs-29	9	1	_	_	PUNCT
asodahs-29	10	1	_	_	PUNCT
asodahs-29	11	1	_	_	PUNCT
asodahs-29	12	1	_	_	PUNCT
asodahs-29	13	1	_	_	PUNCT
asodahs-29	14	1	_	_	PUNCT
asodahs-29	15	1	_	_	PUNCT
asodahs-29	16	1	_	_	PUNCT
asodahs-29	17	1	_	_	PUNCT
asodahs-29	18	1	_	_	PUNCT
asodahs-29	19	1	_	_	PUNCT
asodahs-29	20	1	_	_	PUNCT
asodahs-29	21	1	_	_	PUNCT
asodahs-29	22	1	_	_	PUNCT
asodahs-29	23	1	_	_	PUNCT
asodahs-29	24	1	_	_	PUNCT
asodahs-29	25	1	_	_	PUNCT
asodahs-29	26	1	_	_	PUNCT
asodahs-29	27	1	_	_	PUNCT
asodahs-29	28	1	_	_	PUNCT
asodahs-29	29	1	_	_	PUNCT
asodahs-29	30	1	_	_	PUNCT
asodahs-29	31	1	_	_	PUNCT
asodahs-29	32	1	_	_	PUNCT
asodahs-29	33	1	_	_	PUNCT
asodahs-29	34	1	_	_	PUNCT
asodahs-29	35	1	_	_	PUNCT
asodahs-29	36	1	_	_	PUNCT
asodahs-29	37	1	_	_	PUNCT
asodahs-29	38	1	_	_	PUNCT
asodahs-29	39	1	_	_	PUNCT
asodahs-29	40	1	_	_	PUNCT
asodahs-29	41	1	_	_	PUNCT
asodahs-29	41	2	article	article	NOUN
asodahs-29	41	3	history	history	NOUN
asodahs-29	41	4	:	:	PUNCT
asodahs-29	41	5	received	receive	VERB
asodahs-29	41	6	09	09	NUM
asodahs-29	41	7	sep	sep	NOUN
asodahs-29	41	8	2022	2022	NUM
asodahs-29	41	9	reviewed	review	VERB
asodahs-29	41	10	28	28	NUM
asodahs-29	41	11	oct	oct	NOUN
asodahs-29	41	12	2022	2022	NUM
asodahs-29	41	13	accepted	accept	VERB
asodahs-29	41	14	11	11	NUM
asodahs-29	41	15	nov	nov	NOUN
asodahs-29	41	16	2022	2022	NUM
asodahs-29	41	17	published	publish	VERB
asodahs-29	41	18	28	28	NUM
asodahs-29	41	19	nov	nov	NOUN
asodahs-29	41	20	2022	2022	NUM
asodahs-29	41	21	_	_	PUNCT
asodahs-29	42	1	_	_	PUNCT
asodahs-29	43	1	_	_	PUNCT
asodahs-29	44	1	_	_	PUNCT
asodahs-29	45	1	_	_	PUNCT
asodahs-29	46	1	_	_	PUNCT
asodahs-29	47	1	_	_	PUNCT
asodahs-29	48	1	_	_	PUNCT
asodahs-29	49	1	_	_	PUNCT
asodahs-29	50	1	_	_	PUNCT
asodahs-29	51	1	_	_	PUNCT
asodahs-29	52	1	_	_	PUNCT
asodahs-29	53	1	_	_	PUNCT
asodahs-29	54	1	_	_	PUNCT
asodahs-29	55	1	_	_	PUNCT
asodahs-29	56	1	_	_	PUNCT
asodahs-29	57	1	_	_	PUNCT
asodahs-29	58	1	_	_	PUNCT
asodahs-29	59	1	_	_	PUNCT
asodahs-29	60	1	_	_	PUNCT
asodahs-29	61	1	_	_	PUNCT
asodahs-29	62	1	_	_	PUNCT
asodahs-29	63	1	_	_	PUNCT
asodahs-29	64	1	_	_	PUNCT
asodahs-29	65	1	_	_	PUNCT
asodahs-29	66	1	_	_	PUNCT
asodahs-29	67	1	_	_	PUNCT
asodahs-29	68	1	_	_	PUNCT
asodahs-29	69	1	_	_	PUNCT
asodahs-29	70	1	_	_	PUNCT
asodahs-29	71	1	_	_	PUNCT
asodahs-29	72	1	_	_	PUNCT
asodahs-29	73	1	_	_	PUNCT
asodahs-29	74	1	_	_	PUNCT
asodahs-29	75	1	_	_	PUNCT
asodahs-29	76	1	_	_	PUNCT
asodahs-29	77	1	_	_	PUNCT
asodahs-29	78	1	_	_	PUNCT
asodahs-29	79	1	_	_	PUNCT
asodahs-29	79	2	cite	cite	VERB
asodahs-29	79	3	this	this	DET
asodahs-29	79	4	article	article	NOUN
asodahs-29	79	5	as	as	ADP
asodahs-29	79	6	:	:	PUNCT
asodahs-29	79	7	dangi	dangi	PROPN
asodahs-29	79	8	n	n	CCONJ
asodahs-29	79	9	,	,	PUNCT
asodahs-29	79	10	jain	jain	PROPN
asodahs-29	79	11	sk	sk	PROPN
asodahs-29	79	12	,	,	PUNCT
asodahs-29	79	13	jain	jain	PROPN
asodahs-29	79	14	v	v	PROPN
asodahs-29	79	15	,	,	PUNCT
asodahs-29	79	16	jain	jain	PROPN
asodahs-29	79	17	rk	rk	PROPN
asodahs-29	79	18	,	,	PUNCT
asodahs-29	79	19	khangar	khangar	PROPN
asodahs-29	79	20	pk	pk	PROPN
asodahs-29	79	21	,	,	PUNCT
asodahs-29	79	22	development	development	NOUN
asodahs-29	79	23	and	and	CCONJ
asodahs-29	79	24	characterization	characterization	NOUN
asodahs-29	79	25	of	of	ADP
asodahs-29	79	26	tramadol	tramadol	NOUN
asodahs-29	79	27	hydrochloride	hydrochloride	NOUN
asodahs-29	79	28	rectal	rectal	ADJ
asodahs-29	79	29	suppository	suppository	NOUN
asodahs-29	79	30	,	,	PUNCT
asodahs-29	79	31	asian	asian	ADJ
asodahs-29	79	32	journal	journal	NOUN
asodahs-29	79	33	of	of	ADP
asodahs-29	79	34	dental	dental	ADJ
asodahs-29	79	35	and	and	CCONJ
asodahs-29	79	36	health	health	NOUN
asodahs-29	79	37	sciences	science	NOUN
asodahs-29	79	38	.	.	PUNCT
asodahs-29	79	39	2022	2022	NUM
asodahs-29	79	40	;	;	PUNCT
asodahs-29	79	41	2(3):19	2(3):19	NUM
asodahs-29	79	42	-	-	SYM
asodahs-29	79	43	22	22	NUM
asodahs-29	79	44	doi	doi	NOUN
asodahs-29	79	45	:	:	PUNCT
asodahs-29	79	46	http://dx.doi.org/10.22270/ajdhs.v2i3.29	http://dx.doi.org/10.22270/ajdhs.v2i3.29	NOUN
asodahs-29	79	47	_	_	PUNCT
asodahs-29	80	1	_	_	PUNCT
asodahs-29	81	1	_	_	PUNCT
asodahs-29	82	1	_	_	PUNCT
asodahs-29	83	1	_	_	PUNCT
asodahs-29	84	1	_	_	PUNCT
asodahs-29	85	1	_	_	PUNCT
asodahs-29	86	1	_	_	PUNCT
asodahs-29	87	1	_	_	PUNCT
asodahs-29	88	1	_	_	PUNCT
asodahs-29	89	1	_	_	PUNCT
asodahs-29	90	1	_	_	PUNCT
asodahs-29	91	1	_	_	PUNCT
asodahs-29	92	1	_	_	PUNCT
asodahs-29	93	1	_	_	PUNCT
asodahs-29	94	1	_	_	PUNCT
asodahs-29	95	1	_	_	PUNCT
asodahs-29	96	1	_	_	PUNCT
asodahs-29	97	1	_	_	PUNCT
asodahs-29	98	1	_	_	PUNCT
asodahs-29	99	1	_	_	PUNCT
asodahs-29	100	1	_	_	PUNCT
asodahs-29	101	1	_	_	PUNCT
asodahs-29	102	1	_	_	PUNCT
asodahs-29	103	1	_	_	PUNCT
asodahs-29	104	1	_	_	PUNCT
asodahs-29	105	1	_	_	PUNCT
asodahs-29	106	1	_	_	PUNCT
asodahs-29	107	1	_	_	PUNCT
asodahs-29	108	1	_	_	PUNCT
asodahs-29	109	1	_	_	PUNCT
asodahs-29	110	1	_	_	PUNCT
asodahs-29	111	1	_	_	PUNCT
asodahs-29	112	1	_	_	PUNCT
asodahs-29	113	1	_	_	PUNCT
asodahs-29	114	1	_	_	PUNCT
asodahs-29	115	1	_	_	PUNCT
asodahs-29	116	1	_	_	PUNCT
asodahs-29	117	1	_	_	PUNCT
asodahs-29	118	1	*	*	PUNCT
asodahs-29	118	2	address	address	NOUN
asodahs-29	118	3	for	for	ADP
asodahs-29	118	4	correspondence	correspondence	NOUN
asodahs-29	118	5	:	:	PUNCT
asodahs-29	118	6	pushpendra	pushpendra	PROPN
asodahs-29	118	7	kumar	kumar	PROPN
asodahs-29	118	8	khangar	khangar	PROPN
asodahs-29	118	9	,	,	PUNCT
asodahs-29	118	10	adina	adina	PROPN
asodahs-29	118	11	institute	institute	PROPN
asodahs-29	118	12	of	of	ADP
asodahs-29	118	13	pharmaceutical	pharmaceutical	PROPN
asodahs-29	118	14	sciences	science	NOUN
asodahs-29	118	15	,	,	PUNCT
asodahs-29	118	16	nh86a	nh86a	NOUN
asodahs-29	118	17	,	,	PUNCT
asodahs-29	118	18	lahdara	lahdara	PROPN
asodahs-29	118	19	,	,	PUNCT
asodahs-29	118	20	sagar	sagar	PROPN
asodahs-29	118	21	,	,	PUNCT
asodahs-29	118	22	mp	mp	PROPN
asodahs-29	118	23	,	,	PUNCT
asodahs-29	118	24	470001	470001	NUM
asodahs-29	118	25	,	,	PUNCT
asodahs-29	119	1	india	india	PROPN
asodahs-29	119	2	abstract	abstract	NOUN
asodahs-29	119	3	_	_	PUNCT
asodahs-29	120	1	_	_	PUNCT
asodahs-29	121	1	_	_	PUNCT
asodahs-29	122	1	_	_	PUNCT
asodahs-29	123	1	_	_	PUNCT
asodahs-29	124	1	_	_	PUNCT
asodahs-29	125	1	_	_	PUNCT
asodahs-29	126	1	_	_	PUNCT
asodahs-29	127	1	_	_	PUNCT
asodahs-29	128	1	_	_	PUNCT
asodahs-29	129	1	_	_	PUNCT
asodahs-29	130	1	_	_	PUNCT
asodahs-29	131	1	_	_	PUNCT
asodahs-29	132	1	_	_	PUNCT
asodahs-29	133	1	_	_	PUNCT
asodahs-29	134	1	_	_	PUNCT
asodahs-29	135	1	_	_	PUNCT
asodahs-29	136	1	_	_	PUNCT
asodahs-29	137	1	_	_	PUNCT
asodahs-29	138	1	_	_	PUNCT
asodahs-29	139	1	_	_	PUNCT
asodahs-29	140	1	_	_	PUNCT
asodahs-29	141	1	_	_	PUNCT
asodahs-29	142	1	_	_	PUNCT
asodahs-29	143	1	_	_	PUNCT
asodahs-29	144	1	_	_	PUNCT
asodahs-29	145	1	_	_	PUNCT
asodahs-29	146	1	_	_	PUNCT
asodahs-29	147	1	_	_	PUNCT
asodahs-29	148	1	_	_	PUNCT
asodahs-29	149	1	_	_	PUNCT
asodahs-29	150	1	_	_	PUNCT
asodahs-29	151	1	_	_	PUNCT
asodahs-29	152	1	_	_	PUNCT
asodahs-29	153	1	_	_	PUNCT
asodahs-29	154	1	_	_	PUNCT
asodahs-29	155	1	_	_	PUNCT
asodahs-29	156	1	_	_	PUNCT
asodahs-29	157	1	_	_	PUNCT
asodahs-29	158	1	_	_	PUNCT
asodahs-29	159	1	_	_	PUNCT
asodahs-29	160	1	_	_	PUNCT
asodahs-29	161	1	_	_	PUNCT
asodahs-29	162	1	_	_	PUNCT
asodahs-29	163	1	_	_	PUNCT
asodahs-29	164	1	_	_	PUNCT
asodahs-29	165	1	_	_	PUNCT
asodahs-29	166	1	_	_	PUNCT
asodahs-29	167	1	_	_	PUNCT
asodahs-29	168	1	_	_	PUNCT
asodahs-29	169	1	_	_	PUNCT
asodahs-29	170	1	_	_	PUNCT
asodahs-29	171	1	_	_	PUNCT
asodahs-29	172	1	_	_	PUNCT
asodahs-29	173	1	_	_	PUNCT
asodahs-29	174	1	_	_	PUNCT
asodahs-29	175	1	_	_	PUNCT
asodahs-29	176	1	_	_	PUNCT
asodahs-29	177	1	_	_	PUNCT
asodahs-29	178	1	_	_	PUNCT
asodahs-29	179	1	_	_	PUNCT
asodahs-29	180	1	_	_	PUNCT
asodahs-29	181	1	_	_	PUNCT
asodahs-29	182	1	_	_	PUNCT
asodahs-29	183	1	_	_	PUNCT
asodahs-29	184	1	_	_	PUNCT
asodahs-29	185	1	_	_	PUNCT
asodahs-29	186	1	_	_	PUNCT
asodahs-29	187	1	_	_	PUNCT
asodahs-29	188	1	_	_	PUNCT
asodahs-29	189	1	_	_	PUNCT
asodahs-29	190	1	_	_	PUNCT
asodahs-29	191	1	_	_	PUNCT
asodahs-29	192	1	_	_	PUNCT
asodahs-29	193	1	_	_	PUNCT
asodahs-29	194	1	_	_	PUNCT
asodahs-29	195	1	_	_	PUNCT
asodahs-29	196	1	_	_	PUNCT
asodahs-29	197	1	_	_	PUNCT
asodahs-29	198	1	_	_	PUNCT
asodahs-29	199	1	_	_	PUNCT
asodahs-29	200	1	_	_	PUNCT
asodahs-29	201	1	_	_	PUNCT
asodahs-29	202	1	_	_	PUNCT
asodahs-29	203	1	_	_	PUNCT
asodahs-29	204	1	_	_	PUNCT
asodahs-29	205	1	_	_	PUNCT
asodahs-29	206	1	_	_	PUNCT
asodahs-29	207	1	_	_	PUNCT
asodahs-29	208	1	_	_	PUNCT
asodahs-29	209	1	_	_	PUNCT
asodahs-29	210	1	_	_	PUNCT
asodahs-29	211	1	_	_	PUNCT
asodahs-29	212	1	_	_	PUNCT
asodahs-29	213	1	_	_	PUNCT
asodahs-29	214	1	_	_	PUNCT
asodahs-29	215	1	_	_	PUNCT
asodahs-29	216	1	_	_	PUNCT
asodahs-29	217	1	_	_	PUNCT
asodahs-29	218	1	_	_	PUNCT
asodahs-29	219	1	_	_	PUNCT
asodahs-29	220	1	_	_	PUNCT
asodahs-29	221	1	_	_	PUNCT
asodahs-29	222	1	_	_	PUNCT
asodahs-29	223	1	_	_	PUNCT
asodahs-29	224	1	_	_	PUNCT
asodahs-29	225	1	_	_	PUNCT
asodahs-29	226	1	_	_	PUNCT
asodahs-29	227	1	_	_	PUNCT
asodahs-29	228	1	_	_	PUNCT
asodahs-29	229	1	_	_	PUNCT
asodahs-29	230	1	_	_	PUNCT
asodahs-29	231	1	_	_	PUNCT
asodahs-29	232	1	_	_	PUNCT
asodahs-29	233	1	_	_	PUNCT
asodahs-29	234	1	tramadol	tramadol	NOUN
asodahs-29	234	2	is	be	AUX
asodahs-29	234	3	a	a	DET
asodahs-29	234	4	centrally	centrally	ADV
asodahs-29	234	5	acting	act	VERB
asodahs-29	234	6	analgesic	analgesic	ADJ
asodahs-29	234	7	drug	drug	NOUN
asodahs-29	234	8	.	.	PUNCT
asodahs-29	235	1	rectal	rectal	ADJ
asodahs-29	235	2	administration	administration	NOUN
asodahs-29	235	3	of	of	ADP
asodahs-29	235	4	tramadol	tramadol	NOUN
asodahs-29	235	5	is	be	AUX
asodahs-29	235	6	useful	useful	ADJ
asodahs-29	235	7	in	in	ADP
asodahs-29	235	8	the	the	DET
asodahs-29	235	9	treatment	treatment	NOUN
asodahs-29	235	10	of	of	ADP
asodahs-29	235	11	post	post	ADJ
asodahs-29	235	12	-	-	ADJ
asodahs-29	235	13	operative	operative	ADJ
asodahs-29	235	14	pain	pain	NOUN
asodahs-29	235	15	or	or	CCONJ
asodahs-29	235	16	malignant	malignant	ADJ
asodahs-29	235	17	pain	pain	NOUN
asodahs-29	235	18	in	in	ADP
asodahs-29	235	19	cases	case	NOUN
asodahs-29	235	20	where	where	SCONJ
asodahs-29	235	21	it	it	PRON
asodahs-29	235	22	can	can	AUX
asodahs-29	235	23	not	not	PART
asodahs-29	235	24	be	be	AUX
asodahs-29	235	25	administered	administer	VERB
asodahs-29	235	26	orally	orally	ADV
asodahs-29	235	27	.	.	PUNCT
asodahs-29	236	1	rectal	rectal	ADJ
asodahs-29	236	2	suppositories	suppository	NOUN
asodahs-29	236	3	of	of	ADP
asodahs-29	236	4	tramadol	tramadol	NOUN
asodahs-29	236	5	hydrochloride	hydrochloride	NOUN
asodahs-29	236	6	were	be	AUX
asodahs-29	236	7	prepared	prepare	VERB
asodahs-29	236	8	using	use	VERB
asodahs-29	236	9	different	different	ADJ
asodahs-29	236	10	bases	basis	NOUN
asodahs-29	236	11	and	and	CCONJ
asodahs-29	236	12	polymers	polymer	NOUN
asodahs-29	236	13	and	and	CCONJ
asodahs-29	236	14	the	the	DET
asodahs-29	236	15	effect	effect	NOUN
asodahs-29	236	16	of	of	ADP
asodahs-29	236	17	different	different	ADJ
asodahs-29	236	18	additives	additive	NOUN
asodahs-29	236	19	on	on	ADP
asodahs-29	236	20	in	in	ADP
asodahs-29	236	21	vitro	vitro	X
asodahs-29	236	22	release	release	NOUN
asodahs-29	236	23	of	of	ADP
asodahs-29	236	24	tramadol	tramadol	NOUN
asodahs-29	236	25	hydrochloride	hydrochloride	NOUN
asodahs-29	236	26	was	be	AUX
asodahs-29	236	27	studied	study	VERB
asodahs-29	236	28	.	.	PUNCT
asodahs-29	237	1	the	the	DET
asodahs-29	237	2	agarbased	agarbase	VERB
asodahs-29	237	3	suppositories	suppository	NOUN
asodahs-29	237	4	were	be	AUX
asodahs-29	237	5	non	non	ADJ
asodahs-29	237	6	-	-	ADJ
asodahs-29	237	7	disintegrating	disintegrating	ADJ
asodahs-29	237	8	/	/	SYM
asodahs-29	237	9	non	non	ADJ
asodahs-29	237	10	-	-	ADJ
asodahs-29	237	11	dissolving	dissolving	ADJ
asodahs-29	237	12	.	.	PUNCT
asodahs-29	238	1	all	all	DET
asodahs-29	238	2	the	the	DET
asodahs-29	238	3	prepared	prepared	ADJ
asodahs-29	238	4	suppositories	suppository	NOUN
asodahs-29	238	5	were	be	AUX
asodahs-29	238	6	evaluated	evaluate	VERB
asodahs-29	238	7	for	for	ADP
asodahs-29	238	8	various	various	ADJ
asodahs-29	238	9	physical	physical	ADJ
asodahs-29	238	10	parameters	parameter	NOUN
asodahs-29	238	11	like	like	ADP
asodahs-29	238	12	weight	weight	NOUN
asodahs-29	238	13	variation	variation	NOUN
asodahs-29	238	14	,	,	PUNCT
asodahs-29	238	15	drug	drug	NOUN
asodahs-29	238	16	content	content	NOUN
asodahs-29	238	17	and	and	CCONJ
asodahs-29	238	18	hardness	hardness	NOUN
asodahs-29	238	19	.	.	PUNCT
asodahs-29	239	1	in	in	ADP
asodahs-29	239	2	vitro	vitro	X
asodahs-29	239	3	release	release	NOUN
asodahs-29	239	4	study	study	NOUN
asodahs-29	239	5	was	be	AUX
asodahs-29	239	6	performed	perform	VERB
asodahs-29	239	7	by	by	ADP
asodahs-29	239	8	usp	usp	NOUN
asodahs-29	239	9	type	type	NOUN
asodahs-29	239	10	i	i	PRON
asodahs-29	239	11	apparatus	apparatus	NOUN
asodahs-29	239	12	.	.	PUNCT
asodahs-29	240	1	addition	addition	NOUN
asodahs-29	240	2	of	of	ADP
asodahs-29	240	3	10	10	NUM
asodahs-29	240	4	%	%	NOUN
asodahs-29	240	5	w	w	PROPN
asodahs-29	240	6	/	/	SYM
asodahs-29	240	7	w	w	NOUN
asodahs-29	240	8	propylene	propylene	NOUN
asodahs-29	240	9	glycol	glycol	NOUN
asodahs-29	240	10	accelerates	accelerate	VERB
asodahs-29	240	11	the	the	DET
asodahs-29	240	12	release	release	NOUN
asodahs-29	240	13	of	of	ADP
asodahs-29	240	14	tramadol	tramadol	NOUN
asodahs-29	240	15	hydrochloride	hydrochloride	NOUN
asodahs-29	240	16	significantly	significantly	ADV
asodahs-29	240	17	(	(	PUNCT
asodahs-29	240	18	p<0.05	p<0.05	NOUN
asodahs-29	240	19	)	)	PUNCT
asodahs-29	240	20	as	as	ADP
asodahs-29	240	21	in	in	ADP
asodahs-29	240	22	a1	a1	NOUN
asodahs-29	240	23	,	,	PUNCT
asodahs-29	240	24	which	which	PRON
asodahs-29	240	25	may	may	AUX
asodahs-29	240	26	be	be	AUX
asodahs-29	240	27	due	due	ADJ
asodahs-29	240	28	to	to	PART
asodahs-29	240	29	decrease	decrease	VERB
asodahs-29	240	30	in	in	ADP
asodahs-29	240	31	the	the	DET
asodahs-29	240	32	gel	gel	NOUN
asodahs-29	240	33	matrix	matrix	NOUN
asodahs-29	240	34	of	of	ADP
asodahs-29	240	35	agar	agar	NOUN
asodahs-29	240	36	.	.	PUNCT
asodahs-29	241	1	in	in	ADP
asodahs-29	241	2	formulation	formulation	NOUN
asodahs-29	241	3	a2	a2	PROPN
asodahs-29	241	4	,	,	PUNCT
asodahs-29	241	5	a3	a3	NOUN
asodahs-29	241	6	addition	addition	NOUN
asodahs-29	241	7	of	of	ADP
asodahs-29	241	8	hpmc	hpmc	PROPN
asodahs-29	241	9	(	(	PUNCT
asodahs-29	241	10	1	1	NUM
asodahs-29	241	11	%	%	NOUN
asodahs-29	241	12	,	,	PUNCT
asodahs-29	241	13	3	3	NUM
asodahs-29	241	14	%	%	NOUN
asodahs-29	241	15	w	w	PROPN
asodahs-29	241	16	/	/	SYM
asodahs-29	241	17	w	w	NOUN
asodahs-29	241	18	)	)	PUNCT
asodahs-29	241	19	and	and	CCONJ
asodahs-29	241	20	in	in	ADP
asodahs-29	241	21	formulation	formulation	NOUN
asodahs-29	241	22	a3	a3	NOUN
asodahs-29	241	23	and	and	CCONJ
asodahs-29	241	24	a4	a4	NOUN
asodahs-29	241	25	addition	addition	NOUN
asodahs-29	241	26	of	of	ADP
asodahs-29	241	27	pvp	pvp	NOUN
asodahs-29	241	28	(	(	PUNCT
asodahs-29	241	29	1	1	NUM
asodahs-29	241	30	%	%	NOUN
asodahs-29	241	31	,	,	PUNCT
asodahs-29	241	32	3	3	NUM
asodahs-29	241	33	%	%	NOUN
asodahs-29	241	34	w	w	PROPN
asodahs-29	241	35	/	/	SYM
asodahs-29	241	36	w	w	NOUN
asodahs-29	241	37	)	)	PUNCT
asodahs-29	241	38	retards	retard	VERB
asodahs-29	241	39	the	the	DET
asodahs-29	241	40	release	release	NOUN
asodahs-29	241	41	significantly	significantly	ADV
asodahs-29	241	42	(	(	PUNCT
asodahs-29	241	43	p<0.05	p<0.05	NOUN
asodahs-29	241	44	)	)	PUNCT
asodahs-29	241	45	,	,	PUNCT
asodahs-29	241	46	which	which	PRON
asodahs-29	241	47	may	may	AUX
asodahs-29	241	48	be	be	AUX
asodahs-29	241	49	due	due	ADJ
asodahs-29	241	50	to	to	PART
asodahs-29	241	51	increase	increase	VERB
asodahs-29	241	52	in	in	ADP
asodahs-29	241	53	the	the	DET
asodahs-29	241	54	viscosity	viscosity	NOUN
asodahs-29	241	55	and	and	CCONJ
asodahs-29	241	56	gel	gel	NOUN
asodahs-29	241	57	strength	strength	NOUN
asodahs-29	241	58	of	of	ADP
asodahs-29	241	59	the	the	DET
asodahs-29	241	60	polymer	polymer	NOUN
asodahs-29	241	61	matrix	matrix	NOUN
asodahs-29	241	62	.	.	PUNCT
asodahs-29	242	1	hence	hence	ADV
asodahs-29	242	2	,	,	PUNCT
asodahs-29	242	3	pvp	pvp	PROPN
asodahs-29	242	4	,	,	PUNCT
asodahs-29	242	5	hpmc	hpmc	ADJ
asodahs-29	242	6	and	and	CCONJ
asodahs-29	242	7	similar	similar	ADJ
asodahs-29	242	8	polymers	polymer	NOUN
asodahs-29	242	9	in	in	ADP
asodahs-29	242	10	higher	high	ADJ
asodahs-29	242	11	concentration	concentration	NOUN
asodahs-29	242	12	can	can	AUX
asodahs-29	242	13	be	be	AUX
asodahs-29	242	14	used	use	VERB
asodahs-29	242	15	to	to	PART
asodahs-29	242	16	formulate	formulate	VERB
asodahs-29	242	17	sustained	sustain	VERB
asodahs-29	242	18	released	release	VERB
asodahs-29	242	19	suppositories	suppository	NOUN
asodahs-29	242	20	.	.	PUNCT
asodahs-29	243	1	the	the	DET
asodahs-29	243	2	sustained	sustain	VERB
asodahs-29	243	3	release	release	NOUN
asodahs-29	243	4	suppositories	suppository	NOUN
asodahs-29	243	5	can	can	AUX
asodahs-29	243	6	be	be	AUX
asodahs-29	243	7	prepared	prepare	VERB
asodahs-29	243	8	by	by	ADP
asodahs-29	243	9	addition	addition	NOUN
asodahs-29	243	10	of	of	ADP
asodahs-29	243	11	pvp	pvp	NOUN
asodahs-29	243	12	,	,	PUNCT
asodahs-29	243	13	hpmc	hpmc	PROPN
asodahs-29	243	14	in	in	ADP
asodahs-29	243	15	agar	agar	NOUN
asodahs-29	243	16	-	-	PUNCT
asodahs-29	243	17	based	base	VERB
asodahs-29	243	18	suppositories	suppository	NOUN
asodahs-29	243	19	.	.	PUNCT
asodahs-29	244	1	keywords	keyword	NOUN
asodahs-29	244	2	:	:	PUNCT
asodahs-29	244	3	tramadol	tramadol	NOUN
asodahs-29	244	4	,	,	PUNCT
asodahs-29	244	5	rectal	rectal	ADJ
asodahs-29	244	6	suppositories	suppository	NOUN
asodahs-29	244	7	,	,	PUNCT
asodahs-29	244	8	pvp	pvp	NOUN
asodahs-29	244	9	,	,	PUNCT
asodahs-29	244	10	hpmc	hpmc	ADJ
asodahs-29	244	11	,	,	PUNCT
asodahs-29	244	12	agar	agar	NOUN
asodahs-29	244	13	.	.	PUNCT
asodahs-29	245	1	mail	mail	NOUN
asodahs-29	246	1	i	i	PROPN
asodahs-29	246	2	d	d	PROPN
asodahs-29	246	3	:	:	PUNCT
asodahs-29	247	1	pushpendra.rai16@gmail.com	pushpendra.rai16@gmail.com	PROPN
asodahs-29	247	2	introduction	introduction	NOUN
asodahs-29	247	3	rectal	rectal	ADJ
asodahs-29	247	4	drug	drug	NOUN
asodahs-29	247	5	delivery	delivery	NOUN
asodahs-29	247	6	has	have	VERB
asodahs-29	247	7	a	a	DET
asodahs-29	247	8	number	number	NOUN
asodahs-29	247	9	of	of	ADP
asodahs-29	247	10	advantages	advantage	NOUN
asodahs-29	247	11	such	such	ADJ
asodahs-29	247	12	as	as	ADP
asodahs-29	247	13	reduced	reduce	VERB
asodahs-29	247	14	hepatic	hepatic	ADJ
asodahs-29	247	15	first	first	ADJ
asodahs-29	247	16	pass	pass	NOUN
asodahs-29	247	17	elimination	elimination	NOUN
asodahs-29	247	18	of	of	ADP
asodahs-29	247	19	high	high	ADJ
asodahs-29	247	20	clearance	clearance	NOUN
asodahs-29	247	21	drugs	drug	NOUN
asodahs-29	247	22	,	,	PUNCT
asodahs-29	247	23	avoidance	avoidance	NOUN
asodahs-29	247	24	of	of	ADP
asodahs-29	247	25	gastric	gastric	ADJ
asodahs-29	247	26	irritation	irritation	NOUN
asodahs-29	247	27	associated	associate	VERB
asodahs-29	247	28	with	with	ADP
asodahs-29	247	29	certain	certain	ADJ
asodahs-29	247	30	drugs	drug	NOUN
asodahs-29	247	31	in	in	ADP
asodahs-29	247	32	case	case	NOUN
asodahs-29	247	33	of	of	ADP
asodahs-29	247	34	nausea	nausea	NOUN
asodahs-29	247	35	,	,	PUNCT
asodahs-29	247	36	vomiting	vomiting	NOUN
asodahs-29	247	37	and	and	CCONJ
asodahs-29	247	38	when	when	SCONJ
asodahs-29	247	39	the	the	DET
asodahs-29	247	40	patient	patient	NOUN
asodahs-29	247	41	is	be	AUX
asodahs-29	247	42	unconscious	unconscious	ADJ
asodahs-29	247	43	.	.	PUNCT
asodahs-29	248	1	rectal	rectal	ADJ
asodahs-29	248	2	route	route	NOUN
asodahs-29	248	3	of	of	ADP
asodahs-29	248	4	administration	administration	NOUN
asodahs-29	248	5	is	be	AUX
asodahs-29	248	6	specifically	specifically	ADV
asodahs-29	248	7	useful	useful	ADJ
asodahs-29	248	8	for	for	ADP
asodahs-29	248	9	infants	infant	NOUN
asodahs-29	248	10	and	and	CCONJ
asodahs-29	248	11	children	child	NOUN
asodahs-29	248	12	who	who	PRON
asodahs-29	248	13	have	have	VERB
asodahs-29	248	14	difficulty	difficulty	NOUN
asodahs-29	248	15	in	in	ADP
asodahs-29	248	16	swallowing	swallow	VERB
asodahs-29	248	17	oral	oral	ADJ
asodahs-29	248	18	medicine	medicine	NOUN
asodahs-29	248	19	.	.	PUNCT
asodahs-29	249	1	drug	drug	NOUN
asodahs-29	249	2	administered	administer	VERB
asodahs-29	249	3	in	in	ADP
asodahs-29	249	4	suppository	suppository	ADJ
asodahs-29	249	5	form	form	NOUN
asodahs-29	249	6	can	can	AUX
asodahs-29	249	7	produce	produce	VERB
asodahs-29	249	8	not	not	PART
asodahs-29	249	9	only	only	ADV
asodahs-29	249	10	local	local	ADJ
asodahs-29	249	11	effect	effect	NOUN
asodahs-29	249	12	but	but	CCONJ
asodahs-29	249	13	also	also	ADV
asodahs-29	249	14	systemic	systemic	ADJ
asodahs-29	249	15	therapeutic	therapeutic	ADJ
asodahs-29	249	16	action1	action1	PROPN
asodahs-29	249	17	.	.	PUNCT
asodahs-29	250	1	suppositories	suppository	NOUN
asodahs-29	250	2	can	can	AUX
asodahs-29	250	3	be	be	AUX
asodahs-29	250	4	prepared	prepare	VERB
asodahs-29	250	5	by	by	ADP
asodahs-29	250	6	using	use	VERB
asodahs-29	250	7	lipophilic	lipophilic	ADJ
asodahs-29	250	8	bases	basis	NOUN
asodahs-29	250	9	like	like	ADP
asodahs-29	250	10	cocoa	cocoa	NOUN
asodahs-29	250	11	butter	butter	NOUN
asodahs-29	250	12	or	or	CCONJ
asodahs-29	250	13	by	by	ADP
asodahs-29	250	14	hydrophilic	hydrophilic	ADJ
asodahs-29	250	15	bases	basis	NOUN
asodahs-29	250	16	such	such	ADJ
asodahs-29	250	17	as	as	ADP
asodahs-29	250	18	pegs1	pegs1	NOUN
asodahs-29	250	19	-	-	PUNCT
asodahs-29	250	20	4	4	NUM
asodahs-29	250	21	.	.	PUNCT
asodahs-29	251	1	these	these	DET
asodahs-29	251	2	suppositories	suppository	NOUN
asodahs-29	251	3	melt	melt	VERB
asodahs-29	251	4	or	or	CCONJ
asodahs-29	251	5	dissolve	dissolve	VERB
asodahs-29	251	6	in	in	ADP
asodahs-29	251	7	body	body	NOUN
asodahs-29	251	8	fluids	fluid	NOUN
asodahs-29	251	9	and	and	CCONJ
asodahs-29	251	10	release	release	VERB
asodahs-29	251	11	the	the	DET
asodahs-29	251	12	drug	drug	NOUN
asodahs-29	251	13	,	,	PUNCT
asodahs-29	251	14	but	but	CCONJ
asodahs-29	251	15	are	be	AUX
asodahs-29	251	16	unstable	unstable	ADJ
asodahs-29	251	17	at	at	ADP
asodahs-29	251	18	higher	high	ADJ
asodahs-29	251	19	temperature	temperature	NOUN
asodahs-29	251	20	.	.	PUNCT
asodahs-29	252	1	agar	agar	NOUN
asodahs-29	252	2	has	have	AUX
asodahs-29	252	3	been	be	AUX
asodahs-29	252	4	recently	recently	ADV
asodahs-29	252	5	used	use	VERB
asodahs-29	252	6	as	as	ADP
asodahs-29	252	7	base	base	NOUN
asodahs-29	252	8	to	to	PART
asodahs-29	252	9	produce	produce	VERB
asodahs-29	252	10	non	non	ADJ
asodahs-29	252	11	-	-	ADJ
asodahs-29	252	12	disintegrating/	disintegrating/	VERB
asodahs-29	252	13	nondissolving	nondissolving	ADJ
asodahs-29	252	14	suppositories	suppository	NOUN
asodahs-29	252	15	,	,	PUNCT
asodahs-29	252	16	which	which	PRON
asodahs-29	252	17	are	be	AUX
asodahs-29	252	18	stable	stable	ADJ
asodahs-29	252	19	at	at	ADP
asodahs-29	252	20	higher	high	ADJ
asodahs-29	252	21	temperature5,6	temperature5,6	PROPN
asodahs-29	252	22	.	.	PUNCT
asodahs-29	253	1	tramadol	tramadol	NOUN
asodahs-29	253	2	is	be	AUX
asodahs-29	253	3	a	a	DET
asodahs-29	253	4	synthetic	synthetic	ADJ
asodahs-29	253	5	4	4	NUM
asodahs-29	253	6	-	-	PUNCT
asodahs-29	253	7	phenyl	phenyl	NOUN
asodahs-29	253	8	-	-	PUNCT
asodahs-29	253	9	piperidine	piperidine	NOUN
asodahs-29	253	10	analogue	analogue	NOUN
asodahs-29	253	11	of	of	ADP
asodahs-29	253	12	codeine	codeine	NOUN
asodahs-29	253	13	.	.	PUNCT
asodahs-29	254	1	it	it	PRON
asodahs-29	254	2	is	be	AUX
asodahs-29	254	3	a	a	DET
asodahs-29	254	4	centrally	centrally	ADV
asodahs-29	254	5	acting	act	VERB
asodahs-29	254	6	analgesic	analgesic	NOUN
asodahs-29	254	7	with	with	ADP
asodahs-29	254	8	a	a	DET
asodahs-29	254	9	low	low	ADJ
asodahs-29	254	10	affinity	affinity	NOUN
asodahs-29	254	11	for	for	ADP
asodahs-29	254	12	mu	mu	NOUN
asodahs-29	254	13	opioid	opioid	ADJ
asodahs-29	254	14	receptors	receptor	NOUN
asodahs-29	254	15	(	(	PUNCT
asodahs-29	254	16	a	a	DET
asodahs-29	254	17	class	class	NOUN
asodahs-29	254	18	of	of	ADP
asodahs-29	254	19	opioid	opioid	ADJ
asodahs-29	254	20	receptors	receptor	NOUN
asodahs-29	254	21	with	with	ADP
asodahs-29	254	22	high	high	ADJ
asodahs-29	254	23	affinity	affinity	NOUN
asodahs-29	254	24	for	for	ADP
asodahs-29	254	25	enkephalins	enkephalin	NOUN
asodahs-29	254	26	and	and	CCONJ
asodahs-29	254	27	betaendorphin	betaendorphin	NOUN
asodahs-29	254	28	but	but	CCONJ
asodahs-29	254	29	low	low	ADJ
asodahs-29	254	30	affinity	affinity	NOUN
asodahs-29	254	31	for	for	ADP
asodahs-29	254	32	dynorphins	dynorphin	NOUN
asodahs-29	254	33	)	)	PUNCT
asodahs-29	254	34	.	.	PUNCT
asodahs-29	255	1	it	it	PRON
asodahs-29	255	2	consists	consist	VERB
asodahs-29	255	3	of	of	ADP
asodahs-29	255	4	two	two	NUM
asodahs-29	255	5	enantiomers	enantiomer	NOUN
asodahs-29	255	6	,	,	PUNCT
asodahs-29	255	7	both	both	PRON
asodahs-29	255	8	of	of	ADP
asodahs-29	255	9	which	which	PRON
asodahs-29	255	10	contribute	contribute	VERB
asodahs-29	255	11	to	to	ADP
asodahs-29	255	12	its	its	PRON
asodahs-29	255	13	analgesic	analgesic	ADJ
asodahs-29	255	14	activity	activity	NOUN
asodahs-29	255	15	via	via	ADP
asodahs-29	255	16	different	different	ADJ
asodahs-29	255	17	mechanisms	mechanism	NOUN
asodahs-29	255	18	.	.	PUNCT
asodahs-29	256	1	(	(	PUNCT
asodahs-29	256	2	+	+	NOUN
asodahs-29	256	3	)	)	PUNCT
asodahs-29	256	4	tramadol	tramadol	NOUN
asodahs-29	256	5	and	and	CCONJ
asodahs-29	256	6	its	its	PRON
asodahs-29	256	7	metabolite	metabolite	NOUN
asodahs-29	256	8	(	(	PUNCT
asodahs-29	256	9	+	+	ADJ
asodahs-29	256	10	)	)	PUNCT
asodahs-29	256	11	-o	-o	ADJ
asodahs-29	256	12	-	-	PUNCT
asodahs-29	256	13	desmethyltramodol	desmethyltramodol	ADJ
asodahs-29	256	14	(	(	PUNCT
asodahs-29	256	15	m1	m1	NOUN
asodahs-29	256	16	)	)	PUNCT
asodahs-29	256	17	,	,	PUNCT
asodahs-29	256	18	produced	produce	VERB
asodahs-29	256	19	by	by	ADP
asodahs-29	256	20	liver	liver	NOUN
asodahs-29	256	21	odemethylation	odemethylation	NOUN
asodahs-29	256	22	,	,	PUNCT
asodahs-29	256	23	are	be	AUX
asodahs-29	256	24	agonists	agonist	NOUN
asodahs-29	256	25	of	of	ADP
asodahs-29	256	26	the	the	DET
asodahs-29	256	27	mu	mu	NOUN
asodahs-29	256	28	opioid	opioid	NOUN
asodahs-29	256	29	receptor	receptor	NOUN
asodahs-29	256	30	.	.	PUNCT
asodahs-29	257	1	(	(	PUNCT
asodahs-29	257	2	+	+	NOUN
asodahs-29	257	3	)	)	PUNCT
asodahs-29	257	4	tramadol	tramadol	NOUN
asodahs-29	257	5	also	also	ADV
asodahs-29	257	6	inhibits	inhibit	VERB
asodahs-29	257	7	serotonin	serotonin	NOUN
asodahs-29	257	8	reuptake	reuptake	NOUN
asodahs-29	257	9	whereas	whereas	SCONJ
asodahs-29	257	10	(	(	PUNCT
asodahs-29	257	11	-)tramadol	-)tramadol	NOUN
asodahs-29	257	12	inhibits	inhibit	VERB
asodahs-29	257	13	norepinephrine	norepinephrine	NOUN
asodahs-29	257	14	reuptake	reuptake	NOUN
asodahs-29	257	15	,	,	PUNCT
asodahs-29	257	16	to	to	PART
asodahs-29	257	17	enhance	enhance	VERB
asodahs-29	257	18	the	the	DET
asodahs-29	257	19	inhibition	inhibition	NOUN
asodahs-29	257	20	of	of	ADP
asodahs-29	257	21	pain7,8	pain7,8	PROPN
asodahs-29	257	22	.	.	PUNCT
asodahs-29	258	1	its	its	PRON
asodahs-29	258	2	use	use	NOUN
asodahs-29	258	3	is	be	AUX
asodahs-29	258	4	indicated	indicate	VERB
asodahs-29	258	5	for	for	ADP
asodahs-29	258	6	the	the	DET
asodahs-29	258	7	management	management	NOUN
asodahs-29	258	8	of	of	ADP
asodahs-29	258	9	moderate	moderate	ADJ
asodahs-29	258	10	to	to	PART
asodahs-29	258	11	moderately	moderately	ADV
asodahs-29	258	12	severe	severe	ADJ
asodahs-29	258	13	pain	pain	NOUN
asodahs-29	258	14	including	include	VERB
asodahs-29	258	15	chronic	chronic	ADJ
asodahs-29	258	16	pain	pain	NOUN
asodahs-29	258	17	and	and	CCONJ
asodahs-29	258	18	pain	pain	NOUN
asodahs-29	258	19	associated	associate	VERB
asodahs-29	258	20	with	with	ADP
asodahs-29	258	21	molar	molar	ADJ
asodahs-29	258	22	extraction	extraction	NOUN
asodahs-29	258	23	in	in	ADP
asodahs-29	258	24	adults9	adults9	ADP
asodahs-29	258	25	.	.	PUNCT
asodahs-29	259	1	tramadol	tramadol	NOUN
asodahs-29	259	2	is	be	AUX
asodahs-29	259	3	an	an	DET
asodahs-29	259	4	effective	effective	ADJ
asodahs-29	259	5	and	and	CCONJ
asodahs-29	259	6	well	well	ADV
asodahs-29	259	7	-	-	PUNCT
asodahs-29	259	8	tolerated	tolerate	VERB
asodahs-29	259	9	agent	agent	NOUN
asodahs-29	259	10	to	to	PART
asodahs-29	259	11	reduce	reduce	VERB
asodahs-29	259	12	pain	pain	NOUN
asodahs-29	259	13	resulting	result	VERB
asodahs-29	259	14	from	from	ADP
asodahs-29	259	15	trauma	trauma	NOUN
asodahs-29	259	16	,	,	PUNCT
asodahs-29	259	17	renal	renal	ADJ
asodahs-29	259	18	or	or	CCONJ
asodahs-29	259	19	biliary	biliary	ADJ
asodahs-29	259	20	colic	colic	NOUN
asodahs-29	259	21	,	,	PUNCT
asodahs-29	259	22	and	and	CCONJ
asodahs-29	259	23	labor	labor	NOUN
asodahs-29	259	24	,	,	PUNCT
asodahs-29	259	25	and	and	CCONJ
asodahs-29	259	26	for	for	ADP
asodahs-29	259	27	the	the	DET
asodahs-29	259	28	management	management	NOUN
asodahs-29	259	29	of	of	ADP
asodahs-29	259	30	chronic	chronic	ADJ
asodahs-29	259	31	pain	pain	NOUN
asodahs-29	259	32	of	of	ADP
asodahs-29	259	33	malignant	malignant	ADJ
asodahs-29	259	34	or	or	CCONJ
asodahs-29	259	35	nonmalignant	nonmalignant	ADJ
asodahs-29	259	36	origin	origin	NOUN
asodahs-29	259	37	,	,	PUNCT
asodahs-29	259	38	particularly	particularly	ADV
asodahs-29	259	39	neuropathic	neuropathic	ADJ
asodahs-29	259	40	pain	pain	NOUN
asodahs-29	259	41	.	.	PUNCT
asodahs-29	260	1	tramadol	tramadol	NOUN
asodahs-29	260	2	appears	appear	VERB
asodahs-29	260	3	to	to	PART
asodahs-29	260	4	produce	produce	VERB
asodahs-29	260	5	less	less	ADJ
asodahs-29	260	6	constipation	constipation	NOUN
asodahs-29	260	7	and	and	CCONJ
asodahs-29	260	8	dependence	dependence	NOUN
asodahs-29	260	9	than	than	ADP
asodahs-29	260	10	equianalgesic	equianalgesic	ADJ
asodahs-29	260	11	doses	dose	NOUN
asodahs-29	260	12	of	of	ADP
asodahs-29	260	13	strong	strong	ADJ
asodahs-29	260	14	opioids8	opioids8	NOUN
asodahs-29	260	15	.	.	PUNCT
asodahs-29	261	1	however	however	ADV
asodahs-29	261	2	,	,	PUNCT
asodahs-29	261	3	after	after	ADP
asodahs-29	261	4	intravenous	intravenous	ADJ
asodahs-29	261	5	and	and	CCONJ
asodahs-29	261	6	oral	oral	ADJ
asodahs-29	261	7	administration	administration	NOUN
asodahs-29	261	8	,	,	PUNCT
asodahs-29	261	9	peak	peak	NOUN
asodahs-29	261	10	concentrations	concentration	NOUN
asodahs-29	261	11	are	be	AUX
asodahs-29	261	12	reached	reach	VERB
asodahs-29	261	13	rapidly	rapidly	ADV
asodahs-29	261	14	,	,	PUNCT
asodahs-29	261	15	and	and	CCONJ
asodahs-29	261	16	this	this	PRON
asodahs-29	261	17	has	have	AUX
asodahs-29	261	18	been	be	AUX
asodahs-29	261	19	associated	associate	VERB
asodahs-29	261	20	with	with	ADP
asodahs-29	261	21	postoperative	postoperative	ADJ
asodahs-29	261	22	nausea	nausea	NOUN
asodahs-29	261	23	and	and	CCONJ
asodahs-29	261	24	vomiting10	vomiting10	NOUN
asodahs-29	261	25	.	.	PUNCT
asodahs-29	262	1	thus	thus	ADV
asodahs-29	262	2	,	,	PUNCT
asodahs-29	262	3	this	this	PRON
asodahs-29	262	4	limits	limit	VERB
asodahs-29	262	5	the	the	DET
asodahs-29	262	6	use	use	NOUN
asodahs-29	262	7	of	of	ADP
asodahs-29	262	8	tramadol	tramadol	NOUN
asodahs-29	262	9	as	as	ADP
asodahs-29	262	10	a	a	DET
asodahs-29	262	11	postoperative	postoperative	ADJ
asodahs-29	262	12	analgesic	analgesic	NOUN
asodahs-29	262	13	,	,	PUNCT
asodahs-29	262	14	especially	especially	ADV
asodahs-29	262	15	in	in	ADP
asodahs-29	262	16	day	day	NOUN
asodahs-29	262	17	surgery	surgery	NOUN
asodahs-29	262	18	.	.	PUNCT
asodahs-29	263	1	rectal	rectal	ADJ
asodahs-29	263	2	administration	administration	NOUN
asodahs-29	263	3	of	of	ADP
asodahs-29	263	4	tramadol	tramadol	NOUN
asodahs-29	263	5	may	may	AUX
asodahs-29	263	6	be	be	AUX
asodahs-29	263	7	an	an	DET
asodahs-29	263	8	alternative	alternative	NOUN
asodahs-29	263	9	in	in	ADP
asodahs-29	263	10	this	this	DET
asodahs-29	263	11	situation	situation	NOUN
asodahs-29	263	12	.	.	PUNCT
asodahs-29	264	1	it	it	PRON
asodahs-29	264	2	could	could	AUX
asodahs-29	264	3	be	be	AUX
asodahs-29	264	4	used	use	VERB
asodahs-29	264	5	at	at	ADP
asodahs-29	264	6	the	the	DET
asodahs-29	264	7	same	same	ADJ
asodahs-29	264	8	dose	dose	NOUN
asodahs-29	264	9	range	range	NOUN
asodahs-29	264	10	as	as	ADP
asodahs-29	264	11	that	that	PRON
asodahs-29	264	12	of	of	ADP
asodahs-29	264	13	the	the	DET
asodahs-29	264	14	oral	oral	ADJ
asodahs-29	264	15	form	form	NOUN
asodahs-29	264	16	to	to	PART
asodahs-29	264	17	maintain	maintain	VERB
asodahs-29	264	18	effective	effective	ADJ
asodahs-29	264	19	pain	pain	NOUN
asodahs-29	264	20	relief11	relief11	NOUN
asodahs-29	264	21	.	.	PUNCT
asodahs-29	265	1	furthermore	furthermore	ADV
asodahs-29	265	2	,	,	PUNCT
asodahs-29	265	3	it	it	PRON
asodahs-29	265	4	is	be	AUX
asodahs-29	265	5	useful	useful	ADJ
asodahs-29	265	6	in	in	ADP
asodahs-29	265	7	the	the	DET
asodahs-29	265	8	treatment	treatment	NOUN
asodahs-29	265	9	of	of	ADP
asodahs-29	265	10	post	post	ADJ
asodahs-29	265	11	-	-	ADJ
asodahs-29	265	12	operative	operative	ADJ
asodahs-29	265	13	pain	pain	NOUN
asodahs-29	265	14	or	or	CCONJ
asodahs-29	265	15	malignant	malignant	ADJ
asodahs-29	265	16	pain	pain	NOUN
asodahs-29	265	17	in	in	ADP
asodahs-29	265	18	cases	case	NOUN
asodahs-29	265	19	where	where	SCONJ
asodahs-29	265	20	oral	oral	ADJ
asodahs-29	265	21	administration	administration	NOUN
asodahs-29	265	22	is	be	AUX
asodahs-29	265	23	not	not	PART
asodahs-29	265	24	possible12	possible12	NOUN
asodahs-29	265	25	.	.	PUNCT
asodahs-29	266	1	in	in	ADP
asodahs-29	266	2	the	the	DET
asodahs-29	266	3	present	present	ADJ
asodahs-29	266	4	study	study	NOUN
asodahs-29	266	5	attempts	attempt	NOUN
asodahs-29	266	6	were	be	AUX
asodahs-29	266	7	made	make	VERB
asodahs-29	266	8	to	to	PART
asodahs-29	266	9	formulate	formulate	VERB
asodahs-29	266	10	rectal	rectal	ADJ
asodahs-29	266	11	suppositories	suppository	NOUN
asodahs-29	266	12	of	of	ADP
asodahs-29	266	13	tramadol	tramadol	NOUN
asodahs-29	266	14	hydrochloride	hydrochloride	NOUN
asodahs-29	266	15	with	with	ADP
asodahs-29	266	16	bases	basis	NOUN
asodahs-29	266	17	,	,	PUNCT
asodahs-29	266	18	as	as	SCONJ
asodahs-29	266	19	the	the	DET
asodahs-29	266	20	rectal	rectal	ADJ
asodahs-29	266	21	route	route	NOUN
asodahs-29	266	22	avoids	avoid	VERB
asodahs-29	266	23	first	first	ADJ
asodahs-29	266	24	pass	pass	NOUN
asodahs-29	266	25	metabolism	metabolism	NOUN
asodahs-29	266	26	and	and	CCONJ
asodahs-29	266	27	side	side	NOUN
asodahs-29	266	28	effects	effect	NOUN
asodahs-29	266	29	.	.	PUNCT
asodahs-29	267	1	materials	material	NOUN
asodahs-29	267	2	and	and	CCONJ
asodahs-29	267	3	methods	method	NOUN
asodahs-29	267	4	materials	material	NOUN
asodahs-29	267	5	tramadol	tramadol	NOUN
asodahs-29	267	6	hydrochloride	hydrochloride	NOUN
asodahs-29	267	7	was	be	AUX
asodahs-29	267	8	obtained	obtain	VERB
asodahs-29	267	9	as	as	ADP
asodahs-29	267	10	a	a	DET
asodahs-29	267	11	gift	gift	NOUN
asodahs-29	267	12	sample	sample	NOUN
asodahs-29	267	13	from	from	ADP
asodahs-29	267	14	sun	sun	PROPN
asodahs-29	267	15	pharmaceutical	pharmaceutical	PROPN
asodahs-29	267	16	ltd	ltd	PROPN
asodahs-29	267	17	.	.	PROPN
asodahs-29	267	18	ahmedabad	ahmedabad	PROPN
asodahs-29	267	19	.	.	PUNCT
asodahs-29	268	1	hpmc	hpmc	PROPN
asodahs-29	268	2	and	and	CCONJ
asodahs-29	268	3	pvp	pvp	PROPN
asodahs-29	268	4	were	be	AUX
asodahs-29	268	5	purchased	purchase	VERB
asodahs-29	268	6	from	from	ADP
asodahs-29	268	7	loba	loba	PROPN
asodahs-29	268	8	chemie	chemie	PROPN
asodahs-29	268	9	pvt	pvt	PROPN
asodahs-29	268	10	.	.	PROPN
asodahs-29	268	11	ltd	ltd	PROPN
asodahs-29	268	12	.	.	PROPN
asodahs-29	268	13	,	,	PUNCT
asodahs-29	268	14	mumbai	mumbai	PROPN
asodahs-29	268	15	.	.	PUNCT
asodahs-29	269	1	propylene	propylene	NOUN
asodahs-29	269	2	glycol	glycol	NOUN
asodahs-29	269	3	,	,	PUNCT
asodahs-29	269	4	methyl	methyl	NOUN
asodahs-29	269	5	paraben	paraben	NOUN
asodahs-29	269	6	and	and	CCONJ
asodahs-29	269	7	propyl	propyl	ADJ
asodahs-29	269	8	paraben	paraben	NOUN
asodahs-29	269	9	were	be	AUX
asodahs-29	269	10	purchased	purchase	VERB
asodahs-29	269	11	from	from	ADP
asodahs-29	269	12	s.	s.	PROPN
asodahs-29	269	13	d.	d.	PROPN
asodahs-29	269	14	fine	fine	PROPN
asodahs-29	269	15	chemicals	chemicals	PROPN
asodahs-29	269	16	pvt	pvt	PROPN
asodahs-29	269	17	.	.	PROPN
asodahs-29	269	18	ltd	ltd	PROPN
asodahs-29	269	19	.	.	PROPN
asodahs-29	269	20	,	,	PUNCT
asodahs-29	269	21	mumbai	mumbai	PROPN
asodahs-29	269	22	,	,	PUNCT
asodahs-29	269	23	and	and	CCONJ
asodahs-29	269	24	all	all	DET
asodahs-29	269	25	other	other	ADJ
asodahs-29	269	26	chemicals	chemical	NOUN
asodahs-29	269	27	used	use	VERB
asodahs-29	269	28	were	be	AUX
asodahs-29	269	29	of	of	ADP
asodahs-29	269	30	analytical	analytical	ADJ
asodahs-29	269	31	grade	grade	NOUN
asodahs-29	269	32	and	and	CCONJ
asodahs-29	269	33	were	be	AUX
asodahs-29	269	34	used	use	VERB
asodahs-29	269	35	without	without	ADP
asodahs-29	269	36	any	any	DET
asodahs-29	269	37	further	further	ADJ
asodahs-29	269	38	chemical	chemical	NOUN
asodahs-29	269	39	modification	modification	NOUN
asodahs-29	269	40	.	.	PUNCT
asodahs-29	270	1	open	open	ADJ
asodahs-29	270	2	access	access	NOUN
asodahs-29	270	3	research	research	NOUN
asodahs-29	270	4	article	article	NOUN
asodahs-29	270	5	http://jddtonline.info/	http://jddtonline.info/	PROPN
asodahs-29	270	6	http://dx.doi.org/10.22270/ajdhs.v2i3.29	http://dx.doi.org/10.22270/ajdhs.v2i3.29	NOUN
asodahs-29	270	7	dangi	dangi	PROPN
asodahs-29	270	8	et	et	PROPN
asodahs-29	270	9	al	al	PROPN
asodahs-29	270	10	asian	asian	PROPN
asodahs-29	270	11	journal	journal	PROPN
asodahs-29	270	12	of	of	ADP
asodahs-29	270	13	dental	dental	ADJ
asodahs-29	270	14	and	and	CCONJ
asodahs-29	270	15	health	health	NOUN
asodahs-29	270	16	sciences	science	NOUN
asodahs-29	270	17	.	.	PUNCT
asodahs-29	270	18	2022	2022	NUM
asodahs-29	270	19	;	;	PUNCT
asodahs-29	270	20	2(3):19	2(3):19	NUM
asodahs-29	270	21	-	-	SYM
asodahs-29	270	22	22	22	NUM
asodahs-29	271	1	[	[	X
asodahs-29	271	2	20	20	NUM
asodahs-29	271	3	]	]	PUNCT
asodahs-29	271	4	ajdhs.com	ajdhs.com	X
asodahs-29	271	5	preformulation	preformulation	NOUN
asodahs-29	271	6	studies13	studies13	NOUN
asodahs-29	271	7	,	,	PUNCT
asodahs-29	271	8	14	14	NUM
asodahs-29	271	9	physical	physical	ADJ
asodahs-29	271	10	characteristics	characteristic	NOUN
asodahs-29	271	11	by	by	ADP
asodahs-29	271	12	visual	visual	ADJ
asodahs-29	271	13	examination	examination	NOUN
asodahs-29	271	14	,	,	PUNCT
asodahs-29	271	15	the	the	DET
asodahs-29	271	16	drug	drug	NOUN
asodahs-29	271	17	was	be	AUX
asodahs-29	271	18	identified	identify	VERB
asodahs-29	271	19	for	for	ADP
asodahs-29	271	20	physical	physical	ADJ
asodahs-29	271	21	characters	character	NOUN
asodahs-29	271	22	like	like	ADP
asodahs-29	271	23	colour	colour	NOUN
asodahs-29	271	24	,	,	PUNCT
asodahs-29	271	25	texture	texture	ADJ
asodahs-29	271	26	,	,	PUNCT
asodahs-29	271	27	odour	odour	NOUN
asodahs-29	271	28	etc	etc	X
asodahs-29	271	29	.	.	X
asodahs-29	271	30	solubility	solubility	NOUN
asodahs-29	271	31	solubility	solubility	NOUN
asodahs-29	271	32	of	of	ADP
asodahs-29	271	33	the	the	DET
asodahs-29	271	34	drug	drug	NOUN
asodahs-29	271	35	was	be	AUX
asodahs-29	271	36	determined	determine	VERB
asodahs-29	271	37	by	by	ADP
asodahs-29	271	38	taking	take	VERB
asodahs-29	271	39	some	some	DET
asodahs-29	271	40	quantity	quantity	NOUN
asodahs-29	271	41	of	of	ADP
asodahs-29	271	42	drug	drug	NOUN
asodahs-29	271	43	(	(	PUNCT
asodahs-29	271	44	about	about	ADV
asodahs-29	271	45	10	10	NUM
asodahs-29	271	46	mg	mg	NOUN
asodahs-29	271	47	)	)	PUNCT
asodahs-29	271	48	in	in	ADP
asodahs-29	271	49	the	the	DET
asodahs-29	271	50	10	10	NUM
asodahs-29	271	51	ml	ml	NOUN
asodahs-29	271	52	volumetric	volumetric	NOUN
asodahs-29	271	53	flasks	flask	NOUN
asodahs-29	271	54	separately	separately	ADV
asodahs-29	271	55	and	and	CCONJ
asodahs-29	271	56	added	add	VERB
asodahs-29	271	57	the	the	DET
asodahs-29	271	58	10	10	NUM
asodahs-29	271	59	ml	ml	NOUN
asodahs-29	271	60	of	of	ADP
asodahs-29	271	61	the	the	DET
asodahs-29	271	62	solvent	solvent	NOUN
asodahs-29	271	63	(	(	PUNCT
asodahs-29	271	64	water	water	NOUN
asodahs-29	271	65	,	,	PUNCT
asodahs-29	271	66	ethanol	ethanol	NOUN
asodahs-29	271	67	,	,	PUNCT
asodahs-29	271	68	methanol	methanol	NOUN
asodahs-29	271	69	,	,	PUNCT
asodahs-29	271	70	0.1n	0.1n	PROPN
asodahs-29	271	71	hcl	hcl	PROPN
asodahs-29	271	72	,	,	PUNCT
asodahs-29	271	73	0.1n	0.1n	PROPN
asodahs-29	271	74	naoh	naoh	NOUN
asodahs-29	271	75	,	,	PUNCT
asodahs-29	271	76	chloroform	chloroform	NOUN
asodahs-29	271	77	and	and	CCONJ
asodahs-29	271	78	7.4	7.4	NUM
asodahs-29	271	79	ph	ph	NOUN
asodahs-29	271	80	buffer	buffer	NOUN
asodahs-29	271	81	)	)	PUNCT
asodahs-29	271	82	shake	shake	VERB
asodahs-29	271	83	vigorously	vigorously	ADV
asodahs-29	271	84	and	and	CCONJ
asodahs-29	271	85	kept	keep	VERB
asodahs-29	271	86	for	for	ADP
asodahs-29	271	87	some	some	DET
asodahs-29	271	88	time	time	NOUN
asodahs-29	271	89	.	.	PUNCT
asodahs-29	272	1	note	note	VERB
asodahs-29	272	2	the	the	DET
asodahs-29	272	3	solubility	solubility	NOUN
asodahs-29	272	4	of	of	ADP
asodahs-29	272	5	the	the	DET
asodahs-29	272	6	drug	drug	NOUN
asodahs-29	272	7	in	in	ADP
asodahs-29	272	8	various	various	ADJ
asodahs-29	272	9	solvents	solvent	NOUN
asodahs-29	272	10	(	(	PUNCT
asodahs-29	272	11	at	at	ADP
asodahs-29	272	12	room	room	NOUN
asodahs-29	272	13	temperature	temperature	NOUN
asodahs-29	272	14	)	)	PUNCT
asodahs-29	272	15	.	.	PUNCT
asodahs-29	273	1	melting	melting	NOUN
asodahs-29	273	2	point	point	NOUN
asodahs-29	273	3	a	a	DET
asodahs-29	273	4	small	small	ADJ
asodahs-29	273	5	quantity	quantity	NOUN
asodahs-29	273	6	of	of	ADP
asodahs-29	273	7	powder	powder	NOUN
asodahs-29	273	8	was	be	AUX
asodahs-29	273	9	placed	place	VERB
asodahs-29	273	10	into	into	ADP
asodahs-29	273	11	a	a	DET
asodahs-29	273	12	fusion	fusion	NOUN
asodahs-29	273	13	tube	tube	NOUN
asodahs-29	273	14	.	.	PUNCT
asodahs-29	274	1	that	that	DET
asodahs-29	274	2	tube	tube	NOUN
asodahs-29	274	3	was	be	AUX
asodahs-29	274	4	placed	place	VERB
asodahs-29	274	5	in	in	ADP
asodahs-29	274	6	the	the	DET
asodahs-29	274	7	melting	melting	NOUN
asodahs-29	274	8	point	point	NOUN
asodahs-29	274	9	determining	determine	VERB
asodahs-29	274	10	apparatus	apparatus	NOUN
asodahs-29	274	11	(	(	PUNCT
asodahs-29	274	12	chemline	chemline	NOUN
asodahs-29	274	13	)	)	PUNCT
asodahs-29	274	14	containing	contain	VERB
asodahs-29	274	15	castor	castor	NOUN
asodahs-29	274	16	oil	oil	NOUN
asodahs-29	274	17	.	.	PUNCT
asodahs-29	275	1	the	the	DET
asodahs-29	275	2	temperature	temperature	NOUN
asodahs-29	275	3	of	of	ADP
asodahs-29	275	4	the	the	DET
asodahs-29	275	5	castor	castor	NOUN
asodahs-29	275	6	oil	oil	NOUN
asodahs-29	275	7	was	be	AUX
asodahs-29	275	8	gradual	gradual	ADJ
asodahs-29	275	9	increased	increase	VERB
asodahs-29	275	10	automatically	automatically	ADV
asodahs-29	275	11	and	and	CCONJ
asodahs-29	275	12	read	read	VERB
asodahs-29	275	13	the	the	DET
asodahs-29	275	14	temperature	temperature	NOUN
asodahs-29	275	15	at	at	ADP
asodahs-29	275	16	which	which	PRON
asodahs-29	275	17	powder	powder	NOUN
asodahs-29	275	18	started	start	VERB
asodahs-29	275	19	to	to	PART
asodahs-29	275	20	melt	melt	VERB
asodahs-29	275	21	and	and	CCONJ
asodahs-29	275	22	the	the	DET
asodahs-29	275	23	temperature	temperature	NOUN
asodahs-29	275	24	when	when	SCONJ
asodahs-29	275	25	all	all	DET
asodahs-29	275	26	the	the	DET
asodahs-29	275	27	powder	powder	NOUN
asodahs-29	275	28	gets	get	AUX
asodahs-29	275	29	melted	melt	VERB
asodahs-29	275	30	.	.	PUNCT
asodahs-29	276	1	ftir	ftir	PROPN
asodahs-29	276	2	spectroscopy	spectroscopy	VERB
asodahs-29	276	3	the	the	DET
asodahs-29	276	4	concentration	concentration	NOUN
asodahs-29	276	5	of	of	ADP
asodahs-29	276	6	the	the	DET
asodahs-29	276	7	sample	sample	NOUN
asodahs-29	276	8	in	in	ADP
asodahs-29	276	9	kbr	kbr	PROPN
asodahs-29	276	10	should	should	AUX
asodahs-29	276	11	be	be	AUX
asodahs-29	276	12	in	in	ADP
asodahs-29	276	13	the	the	DET
asodahs-29	276	14	range	range	NOUN
asodahs-29	276	15	of	of	ADP
asodahs-29	276	16	0.2	0.2	NUM
asodahs-29	276	17	%	%	NOUN
asodahs-29	276	18	to	to	PART
asodahs-29	276	19	1	1	NUM
asodahs-29	276	20	%	%	NOUN
asodahs-29	276	21	.	.	PUNCT
asodahs-29	277	1	the	the	DET
asodahs-29	277	2	pellet	pellet	NOUN
asodahs-29	277	3	is	be	AUX
asodahs-29	277	4	a	a	DET
asodahs-29	277	5	lot	lot	NOUN
asodahs-29	277	6	thicker	thick	ADJ
asodahs-29	277	7	than	than	ADP
asodahs-29	277	8	a	a	DET
asodahs-29	277	9	liquid	liquid	ADJ
asodahs-29	277	10	film	film	NOUN
asodahs-29	277	11	,	,	PUNCT
asodahs-29	277	12	consequently	consequently	ADV
asodahs-29	277	13	a	a	DET
asodahs-29	277	14	decrease	decrease	NOUN
asodahs-29	277	15	concentration	concentration	NOUN
asodahs-29	277	16	in	in	ADP
asodahs-29	277	17	the	the	DET
asodahs-29	277	18	sample	sample	NOUN
asodahs-29	277	19	is	be	AUX
asodahs-29	277	20	required	require	VERB
asodahs-29	277	21	(	(	PUNCT
asodahs-29	277	22	beer	beer	NOUN
asodahs-29	277	23	's	's	PART
asodahs-29	277	24	law	law	NOUN
asodahs-29	277	25	)	)	PUNCT
asodahs-29	277	26	.	.	PUNCT
asodahs-29	278	1	for	for	SCONJ
asodahs-29	278	2	the	the	DET
asodahs-29	278	3	die	die	NOUN
asodahs-29	278	4	set	set	VERB
asodahs-29	278	5	that	that	SCONJ
asodahs-29	278	6	you	you	PRON
asodahs-29	278	7	'll	will	AUX
asodahs-29	278	8	be	be	AUX
asodahs-29	278	9	the	the	DET
asodahs-29	278	10	usage	usage	NOUN
asodahs-29	278	11	of	of	ADP
asodahs-29	278	12	,	,	PUNCT
asodahs-29	278	13	about	about	ADV
asodahs-29	278	14	80	80	NUM
asodahs-29	278	15	mg	mg	NOUN
asodahs-29	278	16	of	of	ADP
asodahs-29	278	17	the	the	DET
asodahs-29	278	18	mixture	mixture	NOUN
asodahs-29	278	19	is	be	AUX
asodahs-29	278	20	wanted	want	VERB
asodahs-29	278	21	.	.	PUNCT
asodahs-29	279	1	too	too	ADV
asodahs-29	279	2	excessive	excessive	ADJ
asodahs-29	279	3	of	of	ADP
asodahs-29	279	4	an	an	DET
asodahs-29	279	5	attention	attention	NOUN
asodahs-29	279	6	causes	cause	VERB
asodahs-29	279	7	typically	typically	ADV
asodahs-29	279	8	difficulties	difficulty	NOUN
asodahs-29	279	9	to	to	PART
asodahs-29	279	10	obtain	obtain	VERB
asodahs-29	279	11	clean	clean	ADJ
asodahs-29	279	12	pellets	pellet	NOUN
asodahs-29	279	13	.	.	PUNCT
asodahs-29	280	1	ftir	ftir	PROPN
asodahs-29	280	2	spectra	spectra	PROPN
asodahs-29	280	3	of	of	ADP
asodahs-29	280	4	the	the	DET
asodahs-29	280	5	samples	sample	NOUN
asodahs-29	280	6	were	be	AUX
asodahs-29	280	7	recorded	record	VERB
asodahs-29	280	8	over	over	ADP
asodahs-29	280	9	a	a	DET
asodahs-29	280	10	spectral	spectral	ADJ
asodahs-29	280	11	region	region	NOUN
asodahs-29	280	12	from	from	ADP
asodahs-29	280	13	4700	4700	NUM
asodahs-29	280	14	to	to	ADP
asodahs-29	280	15	400	400	NUM
asodahs-29	280	16	cm-1	cm-1	VERB
asodahs-29	280	17	using	use	VERB
asodahs-29	280	18	20	20	NUM
asodahs-29	280	19	scans	scan	NOUN
asodahs-29	280	20	with	with	ADP
asodahs-29	280	21	4	4	NUM
asodahs-29	280	22	cm-1	cm-1	NOUN
asodahs-29	280	23	resolution	resolution	NOUN
asodahs-29	280	24	.	.	PUNCT
asodahs-29	281	1	determination	determination	NOUN
asodahs-29	281	2	of	of	ADP
asodahs-29	281	3	λ	λ	PROPN
asodahs-29	281	4	max	max	PROPN
asodahs-29	281	5	of	of	ADP
asodahs-29	281	6	tramadol	tramadol	NOUN
asodahs-29	281	7	hcl	hcl	PROPN
asodahs-29	281	8	tramadol	tramadol	NOUN
asodahs-29	281	9	,	,	PUNCT
asodahs-29	281	10	100	100	NUM
asodahs-29	281	11	mg	mg	NUM
asodahs-29	281	12	,	,	PUNCT
asodahs-29	281	13	was	be	AUX
asodahs-29	281	14	accurately	accurately	ADV
asodahs-29	281	15	weighted	weight	VERB
asodahs-29	281	16	into	into	ADP
asodahs-29	281	17	a	a	DET
asodahs-29	281	18	100	100	NUM
asodahs-29	281	19	ml	ml	NOUN
asodahs-29	281	20	volumetric	volumetric	ADJ
asodahs-29	281	21	flask	flask	NOUN
asodahs-29	281	22	,	,	PUNCT
asodahs-29	281	23	dissolved	dissolve	VERB
asodahs-29	281	24	in	in	ADP
asodahs-29	281	25	phosphate	phosphate	ADJ
asodahs-29	281	26	buffer	buffer	NOUN
asodahs-29	281	27	of	of	ADP
asodahs-29	281	28	ph	ph	PROPN
asodahs-29	281	29	6.8	6.8	NUM
asodahs-29	281	30	and	and	CCONJ
asodahs-29	281	31	the	the	DET
asodahs-29	281	32	volume	volume	NOUN
asodahs-29	281	33	was	be	AUX
asodahs-29	281	34	made	make	VERB
asodahs-29	281	35	up	up	ADP
asodahs-29	281	36	with	with	ADP
asodahs-29	281	37	phosphate	phosphate	ADJ
asodahs-29	281	38	buffer	buffer	NOUN
asodahs-29	281	39	of	of	ADP
asodahs-29	281	40	ph	ph	ADJ
asodahs-29	281	41	6.8	6.8	NUM
asodahs-29	281	42	.	.	PUNCT
asodahs-29	282	1	pipette	pipette	NOUN
asodahs-29	282	2	1	1	NUM
asodahs-29	282	3	ml	ml	NOUN
asodahs-29	282	4	of	of	ADP
asodahs-29	282	5	this	this	DET
asodahs-29	282	6	solution	solution	NOUN
asodahs-29	282	7	into	into	ADP
asodahs-29	282	8	a	a	DET
asodahs-29	282	9	10	10	NUM
asodahs-29	282	10	ml	ml	NOUN
asodahs-29	282	11	volumetric	volumetric	ADJ
asodahs-29	282	12	flask	flask	NOUN
asodahs-29	282	13	with	with	ADP
asodahs-29	282	14	phosphate	phosphate	ADJ
asodahs-29	282	15	buffer	buffer	NOUN
asodahs-29	282	16	of	of	ADP
asodahs-29	282	17	ph	ph	ADJ
asodahs-29	282	18	6.8	6.8	NUM
asodahs-29	282	19	as	as	ADP
asodahs-29	282	20	the	the	DET
asodahs-29	282	21	volume	volume	NOUN
asodahs-29	282	22	and	and	CCONJ
asodahs-29	282	23	marks	mark	VERB
asodahs-29	282	24	it	it	PRON
asodahs-29	282	25	as	as	ADP
asodahs-29	282	26	stock	stock	NOUN
asodahs-29	282	27	.	.	PUNCT
asodahs-29	283	1	prepare	prepare	VERB
asodahs-29	283	2	an	an	DET
asodahs-29	283	3	appropriate	appropriate	ADJ
asodahs-29	283	4	dilution	dilution	NOUN
asodahs-29	283	5	to	to	PART
asodahs-29	283	6	bring	bring	VERB
asodahs-29	283	7	the	the	DET
asodahs-29	283	8	concentration	concentration	NOUN
asodahs-29	283	9	down	down	ADP
asodahs-29	283	10	to	to	ADP
asodahs-29	283	11	2.5	2.5	NUM
asodahs-29	283	12	-	-	PUNCT
asodahs-29	283	13	17.5μg	17.5μg	NUM
asodahs-29	283	14	/	/	SYM
asodahs-29	283	15	ml	ml	NOUN
asodahs-29	283	16	.	.	PUNCT
asodahs-29	284	1	the	the	DET
asodahs-29	284	2	resulting	result	VERB
asodahs-29	284	3	solution	solution	NOUN
asodahs-29	284	4	is	be	AUX
asodahs-29	284	5	scanned	scan	VERB
asodahs-29	284	6	with	with	ADP
asodahs-29	284	7	a	a	DET
asodahs-29	284	8	uv	uv	NOUN
asodahs-29	284	9	spectrophotometer	spectrophotometer	NOUN
asodahs-29	284	10	(	(	PUNCT
asodahs-29	284	11	uv-1700	uv-1700	PROPN
asodahs-29	284	12	shimadzu	shimadzu	PROPN
asodahs-29	284	13	corporation	corporation	PROPN
asodahs-29	284	14	,	,	PUNCT
asodahs-29	284	15	japan	japan	PROPN
asodahs-29	284	16	)	)	PUNCT
asodahs-29	284	17	in	in	ADP
asodahs-29	284	18	the	the	DET
asodahs-29	284	19	range	range	NOUN
asodahs-29	284	20	of	of	ADP
asodahs-29	284	21	(	(	PUNCT
asodahs-29	284	22	200	200	NUM
asodahs-29	284	23	-	-	SYM
asodahs-29	284	24	400	400	NUM
asodahs-29	284	25	nm	nm	NOUN
asodahs-29	284	26	)	)	PUNCT
asodahs-29	284	27	to	to	PART
asodahs-29	284	28	determine	determine	VERB
asodahs-29	284	29	the	the	DET
asodahs-29	284	30	absorption	absorption	NOUN
asodahs-29	284	31	maximum	maximum	NOUN
asodahs-29	284	32	(	(	PUNCT
asodahs-29	284	33	λ	λ	X
asodahs-29	284	34	max	max	PROPN
asodahs-29	284	35	)	)	PUNCT
asodahs-29	284	36	.	.	PUNCT
asodahs-29	285	1	concentration	concentration	NOUN
asodahs-29	285	2	vs.	vs.	ADP
asodahs-29	285	3	absorbance	absorbance	NOUN
asodahs-29	285	4	was	be	AUX
asodahs-29	285	5	shown	show	VERB
asodahs-29	285	6	on	on	ADP
asodahs-29	285	7	a	a	DET
asodahs-29	285	8	graph	graph	NOUN
asodahs-29	285	9	.	.	PUNCT
asodahs-29	286	1	preparation	preparation	NOUN
asodahs-29	286	2	of	of	ADP
asodahs-29	286	3	tramadol	tramadol	NOUN
asodahs-29	286	4	hydrochloride	hydrochloride	NOUN
asodahs-29	286	5	rectal	rectal	ADJ
asodahs-29	286	6	suppository	suppository	ADJ
asodahs-29	286	7	agar	agar	NOUN
asodahs-29	286	8	suppositories	suppository	NOUN
asodahs-29	286	9	were	be	AUX
asodahs-29	286	10	prepared	prepare	VERB
asodahs-29	286	11	by	by	ADP
asodahs-29	286	12	molding	mold	VERB
asodahs-29	286	13	method15	method15	NOUN
asodahs-29	286	14	,	,	PUNCT
asodahs-29	286	15	dissolving	dissolve	VERB
asodahs-29	286	16	methyl	methyl	NOUN
asodahs-29	286	17	and	and	CCONJ
asodahs-29	286	18	propyl	propyl	ADJ
asodahs-29	286	19	paraben	paraben	NOUN
asodahs-29	286	20	in	in	ADP
asodahs-29	286	21	hot	hot	ADJ
asodahs-29	286	22	water	water	NOUN
asodahs-29	286	23	and	and	CCONJ
asodahs-29	286	24	then	then	ADV
asodahs-29	286	25	drug	drug	NOUN
asodahs-29	286	26	along	along	ADP
asodahs-29	286	27	with	with	ADP
asodahs-29	286	28	other	other	ADJ
asodahs-29	286	29	additives	additive	NOUN
asodahs-29	286	30	like	like	ADP
asodahs-29	286	31	propylene	propylene	NOUN
asodahs-29	286	32	glycol	glycol	NOUN
asodahs-29	286	33	,	,	PUNCT
asodahs-29	286	34	hpmc	hpmc	PROPN
asodahs-29	286	35	,	,	PUNCT
asodahs-29	286	36	pvp	pvp	PROPN
asodahs-29	286	37	was	be	AUX
asodahs-29	286	38	added	add	VERB
asodahs-29	286	39	and	and	CCONJ
asodahs-29	286	40	mixed	mixed	ADJ
asodahs-29	286	41	well	well	ADV
asodahs-29	286	42	.	.	PUNCT
asodahs-29	287	1	finally	finally	ADV
asodahs-29	287	2	,	,	PUNCT
asodahs-29	287	3	agar	agar	NOUN
asodahs-29	287	4	was	be	AUX
asodahs-29	287	5	incorporated	incorporate	VERB
asodahs-29	287	6	by	by	ADP
asodahs-29	287	7	maintaining	maintain	VERB
asodahs-29	287	8	the	the	DET
asodahs-29	287	9	temperature	temperature	NOUN
asodahs-29	287	10	at	at	ADP
asodahs-29	287	11	75	75	NUM
asodahs-29	287	12	-	-	SYM
asodahs-29	287	13	80	80	NUM
asodahs-29	287	14	℃	℃	PROPN
asodahs-29	287	15	and	and	CCONJ
asodahs-29	287	16	mixed	mixed	ADJ
asodahs-29	287	17	thoroughly	thoroughly	ADV
asodahs-29	287	18	.	.	PUNCT
asodahs-29	288	1	the	the	DET
asodahs-29	288	2	molten	molten	ADJ
asodahs-29	288	3	mass	mass	NOUN
asodahs-29	288	4	was	be	AUX
asodahs-29	288	5	poured	pour	VERB
asodahs-29	288	6	into	into	ADP
asodahs-29	288	7	previously	previously	ADV
asodahs-29	288	8	calibrated	calibrate	VERB
asodahs-29	288	9	stainless	stainless	ADJ
asodahs-29	288	10	-	-	PUNCT
asodahs-29	288	11	steel	steel	NOUN
asodahs-29	288	12	mould	mould	NOUN
asodahs-29	288	13	of	of	ADP
asodahs-29	288	14	1	1	NUM
asodahs-29	288	15	g	g	NOUN
asodahs-29	288	16	and	and	CCONJ
asodahs-29	288	17	allowed	allow	VERB
asodahs-29	288	18	to	to	PART
asodahs-29	288	19	set	set	VERB
asodahs-29	288	20	.	.	PUNCT
asodahs-29	289	1	the	the	DET
asodahs-29	289	2	details	detail	NOUN
asodahs-29	289	3	of	of	ADP
asodahs-29	289	4	all	all	DET
asodahs-29	289	5	formulations	formulation	NOUN
asodahs-29	289	6	are	be	AUX
asodahs-29	289	7	tabulated	tabulate	VERB
asodahs-29	289	8	in	in	ADP
asodahs-29	289	9	table	table	NOUN
asodahs-29	289	10	1	1	NUM
asodahs-29	289	11	.	.	PUNCT
asodahs-29	290	1	all	all	DET
asodahs-29	290	2	the	the	DET
asodahs-29	290	3	prepared	prepared	ADJ
asodahs-29	290	4	suppositories	suppository	NOUN
asodahs-29	290	5	were	be	AUX
asodahs-29	290	6	packed	pack	VERB
asodahs-29	290	7	in	in	ADP
asodahs-29	290	8	polyethylene	polyethylene	NOUN
asodahs-29	290	9	laminated	laminate	VERB
asodahs-29	290	10	foil	foil	NOUN
asodahs-29	290	11	pouches	pouch	NOUN
asodahs-29	290	12	.	.	PUNCT
asodahs-29	291	1	table	table	NOUN
asodahs-29	291	2	1	1	NUM
asodahs-29	291	3	:	:	PUNCT
asodahs-29	291	4	formulations	formulation	NOUN
asodahs-29	291	5	of	of	ADP
asodahs-29	291	6	tramadol	tramadol	NOUN
asodahs-29	291	7	hydrochloride	hydrochloride	NOUN
asodahs-29	291	8	rectal	rectal	ADJ
asodahs-29	291	9	suppositories	suppository	NOUN
asodahs-29	291	10	ingredients	ingredient	NOUN
asodahs-29	291	11	(	(	PUNCT
asodahs-29	291	12	%	%	INTJ
asodahs-29	291	13	w	w	PROPN
asodahs-29	291	14	/	/	SYM
asodahs-29	291	15	w	w	NOUN
asodahs-29	291	16	)	)	PUNCT
asodahs-29	291	17	formulation	formulation	NOUN
asodahs-29	291	18	codes	code	NOUN
asodahs-29	291	19	a0	a0	PROPN
asodahs-29	291	20	a1	a1	PROPN
asodahs-29	291	21	a2	a2	PROPN
asodahs-29	291	22	a3	a3	PROPN
asodahs-29	291	23	a4	a4	PROPN
asodahs-29	291	24	tramadol	tramadol	NOUN
asodahs-29	291	25	hydrochloride	hydrochloride	NOUN
asodahs-29	291	26	5	5	NUM
asodahs-29	291	27	5	5	NUM
asodahs-29	291	28	5	5	NUM
asodahs-29	291	29	5	5	NUM
asodahs-29	291	30	5	5	NUM
asodahs-29	291	31	agar	agar	NOUN
asodahs-29	291	32	10	10	NUM
asodahs-29	291	33	10	10	NUM
asodahs-29	291	34	10	10	NUM
asodahs-29	291	35	10	10	NUM
asodahs-29	291	36	10	10	NUM
asodahs-29	291	37	propylene	propylene	NOUN
asodahs-29	291	38	glycol	glycol	NOUN
asodahs-29	291	39	10	10	NUM
asodahs-29	291	40	10	10	NUM
asodahs-29	291	41	10	10	NUM
asodahs-29	291	42	10	10	NUM
asodahs-29	291	43	methyl	methyl	NOUN
asodahs-29	291	44	paraben	paraben	NOUN
asodahs-29	291	45	0.03	0.03	NUM
asodahs-29	291	46	0.03	0.03	NUM
asodahs-29	291	47	0.03	0.03	NUM
asodahs-29	291	48	0.03	0.03	NUM
asodahs-29	291	49	0.03	0.03	NUM
asodahs-29	291	50	propyl	propyl	NOUN
asodahs-29	291	51	paraben	paraben	NOUN
asodahs-29	291	52	0.02	0.02	NUM
asodahs-29	291	53	0.02	0.02	NUM
asodahs-29	291	54	0.02	0.02	NUM
asodahs-29	291	55	0.02	0.02	NUM
asodahs-29	291	56	0.02	0.02	NUM
asodahs-29	291	57	hpmc	hpmc	ADJ
asodahs-29	291	58	1	1	NUM
asodahs-29	291	59	3	3	NUM
asodahs-29	291	60	pvp	pvp	NOUN
asodahs-29	291	61	1	1	NUM
asodahs-29	291	62	water	water	NOUN
asodahs-29	291	63	qs	qs	NOUN
asodahs-29	291	64	100	100	NUM
asodahs-29	291	65	100	100	NUM
asodahs-29	291	66	100	100	NUM
asodahs-29	291	67	100	100	NUM
asodahs-29	291	68	100	100	NUM
asodahs-29	291	69	evaluation	evaluation	NOUN
asodahs-29	291	70	prepared	prepare	VERB
asodahs-29	291	71	suppositories	suppository	NOUN
asodahs-29	291	72	were	be	AUX
asodahs-29	291	73	visually	visually	ADV
asodahs-29	291	74	inspected	inspect	VERB
asodahs-29	291	75	.	.	PUNCT
asodahs-29	292	1	randomly	randomly	ADV
asodahs-29	292	2	selected	select	VERB
asodahs-29	292	3	suppositories	suppository	NOUN
asodahs-29	292	4	were	be	AUX
asodahs-29	292	5	cut	cut	VERB
asodahs-29	292	6	longitudinally	longitudinally	ADV
asodahs-29	292	7	and	and	CCONJ
asodahs-29	292	8	the	the	DET
asodahs-29	292	9	surfaces	surface	NOUN
asodahs-29	292	10	were	be	AUX
asodahs-29	292	11	examined	examine	VERB
asodahs-29	292	12	with	with	ADP
asodahs-29	292	13	naked	naked	ADJ
asodahs-29	292	14	eye	eye	NOUN
asodahs-29	292	15	.	.	PUNCT
asodahs-29	293	1	for	for	ADP
asodahs-29	293	2	determination	determination	NOUN
asodahs-29	293	3	of	of	ADP
asodahs-29	293	4	weight	weight	NOUN
asodahs-29	293	5	uniformity	uniformity	NOUN
asodahs-29	293	6	,	,	PUNCT
asodahs-29	293	7	twenty	twenty	NUM
asodahs-29	293	8	suppositories	suppository	NOUN
asodahs-29	293	9	were	be	AUX
asodahs-29	293	10	weighed	weigh	VERB
asodahs-29	293	11	individually	individually	ADV
asodahs-29	293	12	and	and	CCONJ
asodahs-29	293	13	the	the	DET
asodahs-29	293	14	average	average	ADJ
asodahs-29	293	15	weights	weight	NOUN
asodahs-29	293	16	were	be	AUX
asodahs-29	293	17	determined16	determined16	ADJ
asodahs-29	293	18	.	.	PUNCT
asodahs-29	294	1	no	no	DET
asodahs-29	294	2	suppositories	suppository	NOUN
asodahs-29	294	3	should	should	AUX
asodahs-29	294	4	deviate	deviate	VERB
asodahs-29	294	5	from	from	ADP
asodahs-29	294	6	average	average	ADJ
asodahs-29	294	7	weight	weight	NOUN
asodahs-29	294	8	by	by	ADP
asodahs-29	294	9	more	more	ADJ
asodahs-29	294	10	than	than	ADP
asodahs-29	294	11	5	5	NUM
asodahs-29	294	12	%	%	NOUN
asodahs-29	294	13	except	except	SCONJ
asodahs-29	294	14	two	two	NUM
asodahs-29	294	15	,	,	PUNCT
asodahs-29	294	16	which	which	PRON
asodahs-29	294	17	may	may	AUX
asodahs-29	294	18	deviate	deviate	VERB
asodahs-29	294	19	by	by	ADP
asodahs-29	294	20	not	not	PART
asodahs-29	294	21	more	more	ADJ
asodahs-29	294	22	than	than	ADP
asodahs-29	294	23	7.5	7.5	NUM
asodahs-29	294	24	%	%	NOUN
asodahs-29	294	25	.	.	PUNCT
asodahs-29	295	1	the	the	DET
asodahs-29	295	2	drug	drug	NOUN
asodahs-29	295	3	content	content	NOUN
asodahs-29	295	4	for	for	ADP
asodahs-29	295	5	agar	agar	NOUN
asodahs-29	295	6	suppositories	suppository	NOUN
asodahs-29	295	7	was	be	AUX
asodahs-29	295	8	determined	determine	VERB
asodahs-29	295	9	by	by	ADP
asodahs-29	295	10	soaking	soak	VERB
asodahs-29	295	11	individual	individual	ADJ
asodahs-29	295	12	suppository	suppository	NOUN
asodahs-29	295	13	in	in	ADP
asodahs-29	295	14	water	water	NOUN
asodahs-29	295	15	for	for	ADP
asodahs-29	295	16	30	30	NUM
asodahs-29	295	17	min	min	NOUN
asodahs-29	295	18	,	,	PUNCT
asodahs-29	295	19	broken	break	VERB
asodahs-29	295	20	with	with	ADP
asodahs-29	295	21	spatula	spatula	NOUN
asodahs-29	295	22	,	,	PUNCT
asodahs-29	295	23	vortexed	vortexe	VERB
asodahs-29	295	24	for	for	ADP
asodahs-29	295	25	5	5	NUM
asodahs-29	295	26	min	min	NOUN
asodahs-29	295	27	,	,	PUNCT
asodahs-29	295	28	filtered	filter	VERB
asodahs-29	295	29	,	,	PUNCT
asodahs-29	295	30	diluted	dilute	VERB
asodahs-29	295	31	to	to	ADP
asodahs-29	295	32	50	50	NUM
asodahs-29	295	33	ml	ml	NOUN
asodahs-29	295	34	with	with	ADP
asodahs-29	295	35	distilled	distil	VERB
asodahs-29	295	36	water	water	NOUN
asodahs-29	295	37	,	,	PUNCT
asodahs-29	295	38	and	and	CCONJ
asodahs-29	295	39	then	then	ADV
asodahs-29	295	40	tramadol	tramadol	NOUN
asodahs-29	295	41	hydrochloride	hydrochloride	NOUN
asodahs-29	295	42	was	be	AUX
asodahs-29	295	43	estimated	estimate	VERB
asodahs-29	295	44	by	by	ADP
asodahs-29	295	45	shimadzu	shimadzu	ADJ
asodahs-29	295	46	uv	uv	NOUN
asodahs-29	295	47	/	/	SYM
asodahs-29	295	48	visible	visible	ADJ
asodahs-29	295	49	spectrophotometer	spectrophotometer	NOUN
asodahs-29	295	50	at	at	ADP
asodahs-29	295	51	271	271	NUM
asodahs-29	295	52	nm	nm	NOUN
asodahs-29	295	53	.	.	PUNCT
asodahs-29	296	1	the	the	DET
asodahs-29	296	2	hardness	hardness	NOUN
asodahs-29	296	3	of	of	ADP
asodahs-29	296	4	the	the	DET
asodahs-29	296	5	prepared	prepare	VERB
asodahs-29	296	6	suppositories	suppository	NOUN
asodahs-29	296	7	was	be	AUX
asodahs-29	296	8	tested	test	VERB
asodahs-29	296	9	using	use	VERB
asodahs-29	296	10	monsanto	monsanto	PROPN
asodahs-29	296	11	hardness	hardness	NOUN
asodahs-29	296	12	tester	tester	NOUN
asodahs-29	296	13	.	.	PUNCT
asodahs-29	297	1	hardness	hardness	ADJ
asodahs-29	297	2	test	test	NOUN
asodahs-29	297	3	or	or	CCONJ
asodahs-29	297	4	breaking	break	VERB
asodahs-29	297	5	strength	strength	NOUN
asodahs-29	297	6	test	test	NOUN
asodahs-29	297	7	was	be	AUX
asodahs-29	297	8	carried	carry	VERB
asodahs-29	297	9	to	to	PART
asodahs-29	297	10	determine	determine	VERB
asodahs-29	297	11	the	the	DET
asodahs-29	297	12	tensile	tensile	NOUN
asodahs-29	297	13	strength	strength	NOUN
asodahs-29	297	14	of	of	ADP
asodahs-29	297	15	the	the	DET
asodahs-29	297	16	suppositories	suppository	NOUN
asodahs-29	297	17	to	to	PART
asodahs-29	297	18	access	access	VERB
asodahs-29	297	19	whether	whether	SCONJ
asodahs-29	297	20	they	they	PRON
asodahs-29	297	21	will	will	AUX
asodahs-29	297	22	be	be	AUX
asodahs-29	297	23	able	able	ADJ
asodahs-29	297	24	to	to	PART
asodahs-29	297	25	withstand	withstand	VERB
asodahs-29	297	26	the	the	DET
asodahs-29	297	27	hazards	hazard	NOUN
asodahs-29	297	28	of	of	ADP
asodahs-29	297	29	packing	packing	NOUN
asodahs-29	297	30	and	and	CCONJ
asodahs-29	297	31	transporting17	transporting17	NOUN
asodahs-29	297	32	.	.	PUNCT
asodahs-29	298	1	usp	usp	PROPN
asodahs-29	298	2	tablet	tablet	NOUN
asodahs-29	298	3	disintegration	disintegration	NOUN
asodahs-29	298	4	apparatus	apparatus	NOUN
asodahs-29	298	5	was	be	AUX
asodahs-29	298	6	employed	employ	VERB
asodahs-29	298	7	to	to	PART
asodahs-29	298	8	measure	measure	VERB
asodahs-29	298	9	the	the	DET
asodahs-29	298	10	melting	melting	NOUN
asodahs-29	298	11	range	range	NOUN
asodahs-29	298	12	of	of	ADP
asodahs-29	298	13	suppositories18	suppositories18	NOUN
asodahs-29	298	14	.	.	PUNCT
asodahs-29	299	1	the	the	DET
asodahs-29	299	2	time	time	NOUN
asodahs-29	299	3	taken	take	VERB
asodahs-29	299	4	for	for	ADP
asodahs-29	299	5	the	the	DET
asodahs-29	299	6	entire	entire	ADJ
asodahs-29	299	7	suppositories	suppository	NOUN
asodahs-29	299	8	to	to	PART
asodahs-29	299	9	melt	melt	VERB
asodahs-29	299	10	/	/	SYM
asodahs-29	299	11	disperse	disperse	NOUN
asodahs-29	299	12	was	be	AUX
asodahs-29	299	13	measured	measure	VERB
asodahs-29	299	14	when	when	SCONJ
asodahs-29	299	15	immersed	immerse	VERB
asodahs-29	299	16	in	in	ADP
asodahs-29	299	17	water	water	NOUN
asodahs-29	299	18	bath	bath	NOUN
asodahs-29	299	19	maintained	maintain	VERB
asodahs-29	299	20	at	at	ADP
asodahs-29	299	21	constant	constant	ADJ
asodahs-29	299	22	temperature	temperature	NOUN
asodahs-29	299	23	of	of	ADP
asodahs-29	299	24	37±0.50c	37±0.50c	PROPN
asodahs-29	299	25	.	.	PUNCT
asodahs-29	300	1	for	for	ADP
asodahs-29	300	2	in	in	ADP
asodahs-29	300	3	vitro	vitro	X
asodahs-29	300	4	dissolution	dissolution	PROPN
asodahs-29	300	5	studies	study	NOUN
asodahs-29	300	6	an	an	DET
asodahs-29	300	7	electrolab	electrolab	NOUN
asodahs-29	300	8	usp	usp	PROPN
asodahs-29	300	9	xxiii	xxiii	PROPN
asodahs-29	300	10	dissolution	dissolution	PROPN
asodahs-29	300	11	apparatus	apparatus	NOUN
asodahs-29	300	12	was	be	AUX
asodahs-29	300	13	used19	used19	NOUN
asodahs-29	300	14	.	.	PUNCT
asodahs-29	301	1	the	the	DET
asodahs-29	301	2	dissolution	dissolution	PROPN
asodahs-29	301	3	medium	medium	NOUN
asodahs-29	301	4	was	be	AUX
asodahs-29	301	5	900	900	NUM
asodahs-29	301	6	ml	ml	NOUN
asodahs-29	301	7	of	of	ADP
asodahs-29	301	8	distilled	distil	VERB
asodahs-29	301	9	water	water	NOUN
asodahs-29	301	10	,	,	PUNCT
asodahs-29	301	11	maintained	maintain	VERB
asodahs-29	301	12	at	at	ADP
asodahs-29	301	13	37±0.50c	37±0.50c	PROPN
asodahs-29	301	14	.	.	PUNCT
asodahs-29	302	1	the	the	DET
asodahs-29	302	2	suppository	suppository	NOUN
asodahs-29	302	3	was	be	AUX
asodahs-29	302	4	placed	place	VERB
asodahs-29	302	5	in	in	ADP
asodahs-29	302	6	the	the	DET
asodahs-29	302	7	metal	metal	NOUN
asodahs-29	302	8	basket	basket	NOUN
asodahs-29	302	9	and	and	CCONJ
asodahs-29	302	10	maintained	maintain	VERB
asodahs-29	302	11	at	at	ADP
asodahs-29	302	12	50	50	NUM
asodahs-29	302	13	rpm	rpm	NOUN
asodahs-29	302	14	.	.	PUNCT
asodahs-29	303	1	ten	ten	NUM
asodahs-29	303	2	millilitres	millilitre	NOUN
asodahs-29	303	3	of	of	ADP
asodahs-29	303	4	sample	sample	NOUN
asodahs-29	303	5	was	be	AUX
asodahs-29	303	6	withdrawn	withdraw	VERB
asodahs-29	303	7	at	at	ADP
asodahs-29	303	8	different	different	ADJ
asodahs-29	303	9	intervals	interval	NOUN
asodahs-29	303	10	of	of	ADP
asodahs-29	303	11	time	time	NOUN
asodahs-29	303	12	(	(	PUNCT
asodahs-29	303	13	10	10	NUM
asodahs-29	303	14	,	,	PUNCT
asodahs-29	303	15	20	20	NUM
asodahs-29	303	16	,	,	PUNCT
asodahs-29	303	17	30	30	NUM
asodahs-29	303	18	,	,	PUNCT
asodahs-29	303	19	45	45	NUM
asodahs-29	303	20	,	,	PUNCT
asodahs-29	303	21	60	60	NUM
asodahs-29	303	22	,	,	PUNCT
asodahs-29	303	23	90	90	NUM
asodahs-29	303	24	,	,	PUNCT
asodahs-29	303	25	120	120	NUM
asodahs-29	303	26	,	,	PUNCT
asodahs-29	303	27	180	180	NUM
asodahs-29	303	28	,	,	PUNCT
asodahs-29	303	29	240	240	NUM
asodahs-29	303	30	min	min	NOUN
asodahs-29	303	31	)	)	PUNCT
asodahs-29	303	32	and	and	CCONJ
asodahs-29	303	33	absorbance	absorbance	NOUN
asodahs-29	303	34	was	be	AUX
asodahs-29	303	35	measured	measure	VERB
asodahs-29	303	36	at	at	ADP
asodahs-29	303	37	271	271	NUM
asodahs-29	303	38	nm	nm	NOUN
asodahs-29	303	39	.	.	PUNCT
asodahs-29	304	1	results	result	NOUN
asodahs-29	304	2	and	and	CCONJ
asodahs-29	304	3	discussions	discussion	NOUN
asodahs-29	304	4	the	the	DET
asodahs-29	304	5	melting	melting	NOUN
asodahs-29	304	6	point	point	NOUN
asodahs-29	304	7	of	of	ADP
asodahs-29	304	8	tramadol	tramadol	NOUN
asodahs-29	304	9	hydrochloride	hydrochloride	NOUN
asodahs-29	304	10	(	(	PUNCT
asodahs-29	304	11	pure	pure	ADJ
asodahs-29	304	12	drug	drug	NOUN
asodahs-29	304	13	)	)	PUNCT
asodahs-29	304	14	was	be	AUX
asodahs-29	304	15	found	find	VERB
asodahs-29	304	16	to	to	PART
asodahs-29	304	17	be	be	AUX
asodahs-29	304	18	180	180	NUM
asodahs-29	304	19	-	-	SYM
asodahs-29	304	20	183	183	NUM
asodahs-29	304	21	°	°	NOUN
asodahs-29	304	22	c	c	NOUN
asodahs-29	304	23	.	.	PUNCT
asodahs-29	305	1	tramadol	tramadol	NOUN
asodahs-29	305	2	hydrochloride	hydrochloride	NOUN
asodahs-29	305	3	was	be	AUX
asodahs-29	305	4	freely	freely	ADV
asodahs-29	305	5	soluble	soluble	ADJ
asodahs-29	305	6	in	in	ADP
asodahs-29	305	7	water	water	NOUN
asodahs-29	305	8	,	,	PUNCT
asodahs-29	305	9	methanol	methanol	NOUN
asodahs-29	305	10	and	and	CCONJ
asodahs-29	305	11	ethanol	ethanol	NOUN
asodahs-29	305	12	,	,	PUNCT
asodahs-29	305	13	soluble	soluble	ADJ
asodahs-29	305	14	in	in	ADP
asodahs-29	305	15	chloroform	chloroform	NOUN
asodahs-29	305	16	and	and	CCONJ
asodahs-29	305	17	pbs	pbs	PROPN
asodahs-29	305	18	6.8	6.8	NUM
asodahs-29	305	19	.	.	PUNCT
asodahs-29	306	1	identification	identification	NOUN
asodahs-29	306	2	of	of	ADP
asodahs-29	306	3	tramadol	tramadol	NOUN
asodahs-29	306	4	hydrochloride	hydrochloride	NOUN
asodahs-29	306	5	was	be	AUX
asodahs-29	306	6	done	do	VERB
asodahs-29	306	7	by	by	ADP
asodahs-29	306	8	ftir	ftir	PROPN
asodahs-29	306	9	spectroscopy	spectroscopy	NOUN
asodahs-29	306	10	with	with	ADP
asodahs-29	306	11	respect	respect	NOUN
asodahs-29	306	12	to	to	ADP
asodahs-29	306	13	marker	marker	NOUN
asodahs-29	306	14	compound	compound	NOUN
asodahs-29	306	15	.	.	PUNCT
asodahs-29	307	1	it	it	PRON
asodahs-29	307	2	was	be	AUX
asodahs-29	307	3	identified	identify	VERB
asodahs-29	307	4	from	from	ADP
asodahs-29	307	5	the	the	DET
asodahs-29	307	6	result	result	NOUN
asodahs-29	307	7	of	of	ADP
asodahs-29	307	8	ir	ir	PROPN
asodahs-29	307	9	spectrum	spectrum	NOUN
asodahs-29	307	10	as	as	ADP
asodahs-29	307	11	per	per	ADP
asodahs-29	307	12	specification	specification	NOUN
asodahs-29	307	13	figure	figure	NOUN
asodahs-29	307	14	1	1	NUM
asodahs-29	307	15	.	.	PUNCT
asodahs-29	308	1	the	the	DET
asodahs-29	308	2	calibration	calibration	NOUN
asodahs-29	308	3	curve	curve	NOUN
asodahs-29	308	4	of	of	ADP
asodahs-29	308	5	tramadol	tramadol	NOUN
asodahs-29	308	6	dangi	dangi	PROPN
asodahs-29	308	7	et	et	PROPN
asodahs-29	308	8	al	al	PROPN
asodahs-29	308	9	asian	asian	PROPN
asodahs-29	308	10	journal	journal	PROPN
asodahs-29	308	11	of	of	ADP
asodahs-29	308	12	dental	dental	ADJ
asodahs-29	308	13	and	and	CCONJ
asodahs-29	308	14	health	health	NOUN
asodahs-29	308	15	sciences	science	NOUN
asodahs-29	308	16	.	.	PUNCT
asodahs-29	308	17	2022	2022	NUM
asodahs-29	308	18	;	;	PUNCT
asodahs-29	308	19	2(3):19	2(3):19	NUM
asodahs-29	308	20	-	-	SYM
asodahs-29	308	21	22	22	NUM
asodahs-29	309	1	[	[	X
asodahs-29	309	2	21	21	NUM
asodahs-29	309	3	]	]	PUNCT
asodahs-29	309	4	ajdhs.com	ajdhs.com	X
asodahs-29	309	5	hydrochloride	hydrochloride	NOUN
asodahs-29	309	6	was	be	AUX
asodahs-29	309	7	found	find	VERB
asodahs-29	309	8	to	to	PART
asodahs-29	309	9	be	be	AUX
asodahs-29	309	10	linear	linear	ADJ
asodahs-29	309	11	in	in	ADP
asodahs-29	309	12	the	the	DET
asodahs-29	309	13	concentration	concentration	NOUN
asodahs-29	309	14	range	range	NOUN
asodahs-29	309	15	of	of	ADP
asodahs-29	309	16	2.5	2.5	NUM
asodahs-29	309	17	-	-	SYM
asodahs-29	309	18	17.5	17.5	NUM
asodahs-29	309	19	µg	µg	NOUN
asodahs-29	309	20	/	/	SYM
asodahs-29	309	21	ml	ml	NOUN
asodahs-29	309	22	at	at	ADP
asodahs-29	309	23	271	271	NUM
asodahs-29	309	24	nm	nm	ADJ
asodahs-29	309	25	figure	figure	NOUN
asodahs-29	309	26	2	2	NUM
asodahs-29	309	27	.	.	PUNCT
asodahs-29	310	1	all	all	DET
asodahs-29	310	2	the	the	DET
asodahs-29	310	3	suppositories	suppository	NOUN
asodahs-29	310	4	were	be	AUX
asodahs-29	310	5	free	free	ADJ
asodahs-29	310	6	from	from	ADP
asodahs-29	310	7	pits	pit	NOUN
asodahs-29	310	8	,	,	PUNCT
asodahs-29	310	9	fissures	fissure	NOUN
asodahs-29	310	10	and	and	CCONJ
asodahs-29	310	11	cracks	crack	NOUN
asodahs-29	310	12	.	.	PUNCT
asodahs-29	311	1	the	the	DET
asodahs-29	311	2	longitudinal	longitudinal	ADJ
asodahs-29	311	3	section	section	NOUN
asodahs-29	311	4	of	of	ADP
asodahs-29	311	5	the	the	DET
asodahs-29	311	6	suppositories	suppository	NOUN
asodahs-29	311	7	was	be	AUX
asodahs-29	311	8	plain	plain	ADJ
asodahs-29	311	9	and	and	CCONJ
asodahs-29	311	10	clear	clear	ADJ
asodahs-29	311	11	.	.	PUNCT
asodahs-29	312	1	the	the	DET
asodahs-29	312	2	results	result	NOUN
asodahs-29	312	3	of	of	ADP
asodahs-29	312	4	different	different	ADJ
asodahs-29	312	5	evaluation	evaluation	NOUN
asodahs-29	312	6	parameters	parameter	NOUN
asodahs-29	312	7	are	be	AUX
asodahs-29	312	8	shown	show	VERB
asodahs-29	312	9	in	in	ADP
asodahs-29	312	10	table	table	NOUN
asodahs-29	312	11	2	2	NUM
asodahs-29	312	12	.	.	PUNCT
asodahs-29	313	1	the	the	DET
asodahs-29	313	2	weight	weight	NOUN
asodahs-29	313	3	variation	variation	NOUN
asodahs-29	313	4	study	study	NOUN
asodahs-29	313	5	for	for	ADP
asodahs-29	313	6	all	all	DET
asodahs-29	313	7	the	the	DET
asodahs-29	313	8	suppositories	suppository	NOUN
asodahs-29	313	9	were	be	AUX
asodahs-29	313	10	found	find	VERB
asodahs-29	313	11	to	to	PART
asodahs-29	313	12	be	be	AUX
asodahs-29	313	13	within	within	ADP
asodahs-29	313	14	the	the	DET
asodahs-29	313	15	acceptable	acceptable	ADJ
asodahs-29	313	16	range	range	NOUN
asodahs-29	313	17	of	of	ADP
asodahs-29	313	18	<	<	X
asodahs-29	313	19	5	5	NUM
asodahs-29	313	20	%	%	NOUN
asodahs-29	313	21	,	,	PUNCT
asodahs-29	313	22	which	which	PRON
asodahs-29	313	23	indicates	indicate	VERB
asodahs-29	313	24	that	that	SCONJ
asodahs-29	313	25	calibration	calibration	NOUN
asodahs-29	313	26	of	of	ADP
asodahs-29	313	27	mold	mold	NOUN
asodahs-29	313	28	was	be	AUX
asodahs-29	313	29	perfect	perfect	ADJ
asodahs-29	313	30	.	.	PUNCT
asodahs-29	314	1	all	all	DET
asodahs-29	314	2	the	the	DET
asodahs-29	314	3	prepared	prepared	ADJ
asodahs-29	314	4	suppositories	suppository	NOUN
asodahs-29	314	5	showed	show	VERB
asodahs-29	314	6	uniformity	uniformity	NOUN
asodahs-29	314	7	in	in	ADP
asodahs-29	314	8	drug	drug	NOUN
asodahs-29	314	9	content	content	NOUN
asodahs-29	314	10	and	and	CCONJ
asodahs-29	314	11	were	be	AUX
asodahs-29	314	12	within	within	ADP
asodahs-29	314	13	the	the	DET
asodahs-29	314	14	permissible	permissible	ADJ
asodahs-29	314	15	range	range	NOUN
asodahs-29	314	16	(	(	PUNCT
asodahs-29	314	17	97	97	NUM
asodahs-29	314	18	%	%	NOUN
asodahs-29	314	19	to	to	PART
asodahs-29	314	20	105	105	NUM
asodahs-29	314	21	%	%	NOUN
asodahs-29	314	22	)	)	PUNCT
asodahs-29	314	23	indicating	indicate	VERB
asodahs-29	314	24	uniformity	uniformity	NOUN
asodahs-29	314	25	of	of	ADP
asodahs-29	314	26	drug	drug	NOUN
asodahs-29	314	27	dispersion	dispersion	NOUN
asodahs-29	314	28	in	in	ADP
asodahs-29	314	29	suppositories	suppository	NOUN
asodahs-29	314	30	.	.	PUNCT
asodahs-29	315	1	the	the	DET
asodahs-29	315	2	suppositories	suppository	NOUN
asodahs-29	315	3	should	should	AUX
asodahs-29	315	4	have	have	VERB
asodahs-29	315	5	good	good	ADJ
asodahs-29	315	6	mechanical	mechanical	ADJ
asodahs-29	315	7	strength	strength	NOUN
asodahs-29	315	8	for	for	ADP
asodahs-29	315	9	handling	handling	NOUN
asodahs-29	315	10	and	and	CCONJ
asodahs-29	315	11	transportation	transportation	NOUN
asodahs-29	315	12	.	.	PUNCT
asodahs-29	316	1	all	all	DET
asodahs-29	316	2	the	the	DET
asodahs-29	316	3	suppositories	suppository	NOUN
asodahs-29	316	4	were	be	AUX
asodahs-29	316	5	having	have	VERB
asodahs-29	316	6	good	good	ADJ
asodahs-29	316	7	mechanical	mechanical	ADJ
asodahs-29	316	8	strength	strength	NOUN
asodahs-29	316	9	in	in	ADP
asodahs-29	316	10	the	the	DET
asodahs-29	316	11	range	range	NOUN
asodahs-29	316	12	of	of	ADP
asodahs-29	316	13	1.50	1.50	NUM
asodahs-29	316	14	to	to	ADP
asodahs-29	316	15	2.00	2.00	NUM
asodahs-29	316	16	kg	kg	NOUN
asodahs-29	316	17	/	/	SYM
asodahs-29	316	18	cm²	cm²	NOUN
asodahs-29	316	19	showing	show	VERB
asodahs-29	316	20	optimum	optimum	ADJ
asodahs-29	316	21	hardness	hardness	NOUN
asodahs-29	316	22	.	.	PUNCT
asodahs-29	317	1	dissolution	dissolution	PROPN
asodahs-29	317	2	study	study	NOUN
asodahs-29	317	3	of	of	ADP
asodahs-29	317	4	agar	agar	NOUN
asodahs-29	317	5	-	-	PUNCT
asodahs-29	317	6	based	base	VERB
asodahs-29	317	7	suppositories	suppository	NOUN
asodahs-29	317	8	indicated	indicate	VERB
asodahs-29	317	9	that	that	SCONJ
asodahs-29	317	10	the	the	DET
asodahs-29	317	11	suppository	suppository	NOUN
asodahs-29	317	12	does	do	AUX
asodahs-29	317	13	not	not	PART
asodahs-29	317	14	disintegrate	disintegrate	VERB
asodahs-29	317	15	,	,	PUNCT
asodahs-29	317	16	melt	melt	VERB
asodahs-29	317	17	or	or	CCONJ
asodahs-29	317	18	dissolve	dissolve	VERB
asodahs-29	317	19	in	in	ADP
asodahs-29	317	20	the	the	DET
asodahs-29	317	21	dissolution	dissolution	NOUN
asodahs-29	317	22	medium	medium	NOUN
asodahs-29	317	23	but	but	CCONJ
asodahs-29	317	24	remains	remain	VERB
asodahs-29	317	25	intact	intact	ADJ
asodahs-29	317	26	.	.	PUNCT
asodahs-29	318	1	the	the	DET
asodahs-29	318	2	drug	drug	NOUN
asodahs-29	318	3	diffuses	diffuse	VERB
asodahs-29	318	4	out	out	ADP
asodahs-29	318	5	from	from	ADP
asodahs-29	318	6	the	the	DET
asodahs-29	318	7	hydrophilic	hydrophilic	ADJ
asodahs-29	318	8	matrix	matrix	NOUN
asodahs-29	318	9	with	with	ADP
asodahs-29	318	10	time	time	NOUN
asodahs-29	318	11	.	.	PUNCT
asodahs-29	319	1	it	it	PRON
asodahs-29	319	2	was	be	AUX
asodahs-29	319	3	observed	observe	VERB
asodahs-29	319	4	that	that	SCONJ
asodahs-29	319	5	more	more	ADJ
asodahs-29	319	6	than	than	ADP
asodahs-29	319	7	50	50	NUM
asodahs-29	319	8	%	%	NOUN
asodahs-29	319	9	of	of	ADP
asodahs-29	319	10	the	the	DET
asodahs-29	319	11	drug	drug	NOUN
asodahs-29	319	12	was	be	AUX
asodahs-29	319	13	released	release	VERB
asodahs-29	319	14	from	from	ADP
asodahs-29	319	15	a0	a0	NOUN
asodahs-29	319	16	formulation	formulation	NOUN
asodahs-29	319	17	within	within	ADP
asodahs-29	319	18	60	60	NUM
asodahs-29	319	19	min	min	NOUN
asodahs-29	319	20	.	.	NOUN
asodahs-29	319	21	addition	addition	NOUN
asodahs-29	319	22	of	of	ADP
asodahs-29	319	23	10	10	NUM
asodahs-29	319	24	%	%	NOUN
asodahs-29	319	25	w	w	PROPN
asodahs-29	319	26	/	/	SYM
asodahs-29	319	27	w	w	NOUN
asodahs-29	319	28	propylene	propylene	NOUN
asodahs-29	319	29	glycol	glycol	NOUN
asodahs-29	319	30	accelerates	accelerate	VERB
asodahs-29	319	31	the	the	DET
asodahs-29	319	32	release	release	NOUN
asodahs-29	319	33	of	of	ADP
asodahs-29	319	34	tramadol	tramadol	NOUN
asodahs-29	319	35	hydrochloride	hydrochloride	NOUN
asodahs-29	319	36	significantly	significantly	ADV
asodahs-29	319	37	(	(	PUNCT
asodahs-29	319	38	p<0.05	p<0.05	NOUN
asodahs-29	319	39	)	)	PUNCT
asodahs-29	319	40	as	as	ADP
asodahs-29	319	41	in	in	ADP
asodahs-29	319	42	a1	a1	NOUN
asodahs-29	319	43	,	,	PUNCT
asodahs-29	319	44	which	which	PRON
asodahs-29	319	45	may	may	AUX
asodahs-29	319	46	be	be	AUX
asodahs-29	319	47	due	due	ADJ
asodahs-29	319	48	to	to	PART
asodahs-29	319	49	decrease	decrease	VERB
asodahs-29	319	50	in	in	ADP
asodahs-29	319	51	the	the	DET
asodahs-29	319	52	gel	gel	NOUN
asodahs-29	319	53	matrix	matrix	NOUN
asodahs-29	319	54	of	of	ADP
asodahs-29	319	55	agar	agar	NOUN
asodahs-29	319	56	.	.	PUNCT
asodahs-29	320	1	in	in	ADP
asodahs-29	320	2	formulation	formulation	NOUN
asodahs-29	320	3	a2	a2	PROPN
asodahs-29	320	4	,	,	PUNCT
asodahs-29	320	5	a3	a3	NOUN
asodahs-29	320	6	addition	addition	NOUN
asodahs-29	320	7	of	of	ADP
asodahs-29	320	8	hpmc	hpmc	PROPN
asodahs-29	320	9	(	(	PUNCT
asodahs-29	320	10	1	1	NUM
asodahs-29	320	11	%	%	NOUN
asodahs-29	320	12	,	,	PUNCT
asodahs-29	320	13	3	3	NUM
asodahs-29	320	14	%	%	NOUN
asodahs-29	320	15	w	w	PROPN
asodahs-29	320	16	/	/	SYM
asodahs-29	320	17	w	w	NOUN
asodahs-29	320	18	)	)	PUNCT
asodahs-29	320	19	and	and	CCONJ
asodahs-29	320	20	in	in	ADP
asodahs-29	320	21	formulation	formulation	NOUN
asodahs-29	320	22	a3	a3	NOUN
asodahs-29	320	23	,	,	PUNCT
asodahs-29	320	24	a4	a4	NOUN
asodahs-29	320	25	addition	addition	NOUN
asodahs-29	320	26	of	of	ADP
asodahs-29	320	27	pvp	pvp	NOUN
asodahs-29	320	28	(	(	PUNCT
asodahs-29	320	29	1	1	NUM
asodahs-29	320	30	%	%	NOUN
asodahs-29	320	31	,	,	PUNCT
asodahs-29	320	32	3	3	NUM
asodahs-29	320	33	%	%	NOUN
asodahs-29	320	34	w	w	PROPN
asodahs-29	320	35	/	/	SYM
asodahs-29	320	36	w	w	NOUN
asodahs-29	320	37	)	)	PUNCT
asodahs-29	320	38	retards	retard	VERB
asodahs-29	320	39	the	the	DET
asodahs-29	320	40	release	release	NOUN
asodahs-29	320	41	significantly	significantly	ADV
asodahs-29	320	42	(	(	PUNCT
asodahs-29	320	43	p<0.05	p<0.05	NOUN
asodahs-29	320	44	)	)	PUNCT
asodahs-29	320	45	,	,	PUNCT
asodahs-29	320	46	which	which	PRON
asodahs-29	320	47	may	may	AUX
asodahs-29	320	48	be	be	AUX
asodahs-29	320	49	due	due	ADJ
asodahs-29	320	50	to	to	PART
asodahs-29	320	51	increase	increase	VERB
asodahs-29	320	52	in	in	ADP
asodahs-29	320	53	the	the	DET
asodahs-29	320	54	viscosity	viscosity	NOUN
asodahs-29	320	55	and	and	CCONJ
asodahs-29	320	56	gel	gel	NOUN
asodahs-29	320	57	strength	strength	NOUN
asodahs-29	320	58	of	of	ADP
asodahs-29	320	59	the	the	DET
asodahs-29	320	60	polymer	polymer	NOUN
asodahs-29	320	61	matrix	matrix	NOUN
asodahs-29	320	62	.	.	PUNCT
asodahs-29	321	1	hence	hence	ADV
asodahs-29	321	2	,	,	PUNCT
asodahs-29	321	3	pvp	pvp	PROPN
asodahs-29	321	4	,	,	PUNCT
asodahs-29	321	5	hpmc	hpmc	ADJ
asodahs-29	321	6	and	and	CCONJ
asodahs-29	321	7	similar	similar	ADJ
asodahs-29	321	8	polymers	polymer	NOUN
asodahs-29	321	9	in	in	ADP
asodahs-29	321	10	higher	high	ADJ
asodahs-29	321	11	concentration	concentration	NOUN
asodahs-29	321	12	can	can	AUX
asodahs-29	321	13	be	be	AUX
asodahs-29	321	14	used	use	VERB
asodahs-29	321	15	to	to	PART
asodahs-29	321	16	formulate	formulate	VERB
asodahs-29	321	17	sustained	sustained	ADJ
asodahs-29	321	18	released	release	VERB
asodahs-29	321	19	suppositories	suppository	NOUN
asodahs-29	321	20	table	table	VERB
asodahs-29	321	21	3	3	NUM
asodahs-29	321	22	.	.	PUNCT
asodahs-29	321	23	figure	figure	NOUN
asodahs-29	321	24	1	1	NUM
asodahs-29	321	25	:	:	PUNCT
asodahs-29	321	26	ft	ft	PROPN
asodahs-29	321	27	-	-	PUNCT
asodahs-29	321	28	ir	ir	NOUN
asodahs-29	321	29	spectrum	spectrum	NOUN
asodahs-29	321	30	of	of	ADP
asodahs-29	321	31	pure	pure	ADJ
asodahs-29	321	32	drug	drug	NOUN
asodahs-29	321	33	(	(	PUNCT
asodahs-29	321	34	tramadol	tramadol	NOUN
asodahs-29	321	35	hydrochloride	hydrochloride	NOUN
asodahs-29	321	36	)	)	PUNCT
asodahs-29	321	37	figure	figure	NOUN
asodahs-29	321	38	2	2	NUM
asodahs-29	321	39	:	:	PUNCT
asodahs-29	321	40	wavelength	wavelength	NOUN
asodahs-29	321	41	maxima	maxima	NOUN
asodahs-29	321	42	of	of	ADP
asodahs-29	321	43	tramadol	tramadol	NOUN
asodahs-29	321	44	hydrochloride	hydrochloride	NOUN
asodahs-29	321	45	in	in	ADP
asodahs-29	321	46	pbs	pbs	PROPN
asodahs-29	321	47	6.8	6.8	NUM
asodahs-29	321	48	table	table	NOUN
asodahs-29	321	49	2	2	NUM
asodahs-29	321	50	:	:	PUNCT
asodahs-29	321	51	evaluation	evaluation	NOUN
asodahs-29	321	52	of	of	ADP
asodahs-29	321	53	suppositories	suppository	NOUN
asodahs-29	321	54	for	for	ADP
asodahs-29	321	55	various	various	ADJ
asodahs-29	321	56	parameters	parameter	NOUN
asodahs-29	321	57	formulation	formulation	NOUN
asodahs-29	321	58	code	code	NOUN
asodahs-29	321	59	drug	drug	NOUN
asodahs-29	321	60	content	content	NOUN
asodahs-29	321	61	*	*	PUNCT
asodahs-29	321	62	(	(	PUNCT
asodahs-29	321	63	%	%	INTJ
asodahs-29	321	64	)	)	PUNCT
asodahs-29	321	65	weight	weight	NOUN
asodahs-29	321	66	variation	variation	NOUN
asodahs-29	321	67	±sd	±sd	PROPN
asodahs-29	321	68	(	(	PUNCT
asodahs-29	321	69	g	g	NOUN
asodahs-29	321	70	)	)	PUNCT
asodahs-29	321	71	hardness	hardness	NOUN
asodahs-29	321	72	*	*	PUNCT
asodahs-29	321	73	(	(	PUNCT
asodahs-29	321	74	kg	kg	NOUN
asodahs-29	321	75	/	/	SYM
asodahs-29	321	76	cm2	cm2	NOUN
asodahs-29	321	77	)	)	PUNCT
asodahs-29	321	78	a0	a0	NOUN
asodahs-29	321	79	97.55	97.55	NUM
asodahs-29	321	80	1.008±0.04	1.008±0.04	NUM
asodahs-29	321	81	1.50	1.50	NUM
asodahs-29	321	82	a1	a1	NOUN
asodahs-29	321	83	97.00	97.00	NUM
asodahs-29	321	84	0.997±0.04	0.997±0.04	NUM
asodahs-29	321	85	2.00	2.00	NUM
asodahs-29	321	86	a2	a2	NOUN
asodahs-29	321	87	98.10	98.10	NUM
asodahs-29	321	88	0.998±0.03	0.998±0.03	NUM
asodahs-29	321	89	2.00	2.00	NUM
asodahs-29	321	90	a3	a3	NOUN
asodahs-29	321	91	101.30	101.30	NUM
asodahs-29	321	92	1.001±0.01	1.001±0.01	NUM
asodahs-29	321	93	2.00	2.00	NUM
asodahs-29	321	94	a4	a4	NOUN
asodahs-29	321	95	105.00	105.00	NUM
asodahs-29	321	96	1.002±0.02	1.002±0.02	NUM
asodahs-29	321	97	2.00	2.00	NUM
asodahs-29	321	98	dangi	dangi	NOUN
asodahs-29	321	99	et	et	PROPN
asodahs-29	321	100	al	al	PROPN
asodahs-29	321	101	asian	asian	PROPN
asodahs-29	321	102	journal	journal	PROPN
asodahs-29	321	103	of	of	ADP
asodahs-29	321	104	dental	dental	ADJ
asodahs-29	321	105	and	and	CCONJ
asodahs-29	321	106	health	health	NOUN
asodahs-29	321	107	sciences	science	NOUN
asodahs-29	321	108	.	.	PUNCT
asodahs-29	321	109	2022	2022	NUM
asodahs-29	321	110	;	;	PUNCT
asodahs-29	321	111	2(3):19	2(3):19	NUM
asodahs-29	321	112	-	-	SYM
asodahs-29	321	113	22	22	NUM
asodahs-29	322	1	[	[	X
asodahs-29	322	2	22	22	NUM
asodahs-29	322	3	]	]	PUNCT
asodahs-29	322	4	ajdhs.com	ajdhs.com	X
asodahs-29	322	5	table	table	NOUN
asodahs-29	322	6	3	3	NUM
asodahs-29	322	7	:	:	PUNCT
asodahs-29	322	8	in	in	ADP
asodahs-29	322	9	vitro	vitro	X
asodahs-29	322	10	release	release	NOUN
asodahs-29	322	11	of	of	ADP
asodahs-29	322	12	tramadol	tramadol	NOUN
asodahs-29	322	13	hydrochloride	hydrochloride	NOUN
asodahs-29	322	14	from	from	ADP
asodahs-29	322	15	suppositories	suppository	NOUN
asodahs-29	322	16	time	time	NOUN
asodahs-29	322	17	(	(	PUNCT
asodahs-29	322	18	min	min	NOUN
asodahs-29	322	19	)	)	PUNCT
asodahs-29	322	20	%	%	NOUN
asodahs-29	322	21	drug	drug	NOUN
asodahs-29	322	22	release	release	NOUN
asodahs-29	322	23	a0	a0	PROPN
asodahs-29	322	24	a1	a1	PROPN
asodahs-29	322	25	a2	a2	PROPN
asodahs-29	322	26	a3	a3	PROPN
asodahs-29	322	27	a4	a4	PROPN
asodahs-29	322	28	40	40	NUM
asodahs-29	322	29	30	30	NUM
asodahs-29	322	30	60	60	NUM
asodahs-29	322	31	45	45	NUM
asodahs-29	322	32	20	20	NUM
asodahs-29	322	33	50	50	NUM
asodahs-29	322	34	80	80	NUM
asodahs-29	322	35	40	40	NUM
asodahs-29	322	36	72	72	NUM
asodahs-29	322	37	55	55	NUM
asodahs-29	322	38	30	30	NUM
asodahs-29	322	39	59	59	NUM
asodahs-29	322	40	120	120	NUM
asodahs-29	322	41	50	50	NUM
asodahs-29	322	42	78	78	NUM
asodahs-29	322	43	60	60	NUM
asodahs-29	322	44	35	35	NUM
asodahs-29	322	45	62	62	NUM
asodahs-29	322	46	160	160	NUM
asodahs-29	322	47	60	60	NUM
asodahs-29	322	48	80	80	NUM
asodahs-29	322	49	65	65	NUM
asodahs-29	322	50	40	40	NUM
asodahs-29	322	51	65	65	NUM
asodahs-29	322	52	200	200	NUM
asodahs-29	322	53	65	65	NUM
asodahs-29	322	54	82	82	NUM
asodahs-29	322	55	70	70	NUM
asodahs-29	322	56	45	45	NUM
asodahs-29	322	57	68	68	NUM
asodahs-29	322	58	240	240	NUM
asodahs-29	322	59	70	70	NUM
asodahs-29	322	60	85	85	NUM
asodahs-29	322	61	75	75	NUM
asodahs-29	322	62	55	55	NUM
asodahs-29	322	63	70	70	NUM
asodahs-29	322	64	conclusion	conclusion	NOUN
asodahs-29	322	65	in	in	ADP
asodahs-29	322	66	conclusion	conclusion	NOUN
asodahs-29	322	67	,	,	PUNCT
asodahs-29	322	68	tramadol	tramadol	NOUN
asodahs-29	322	69	hydrochloride	hydrochloride	NOUN
asodahs-29	322	70	suppositories	suppository	NOUN
asodahs-29	322	71	prepared	prepare	VERB
asodahs-29	322	72	using	use	VERB
asodahs-29	322	73	bases	basis	NOUN
asodahs-29	322	74	showed	show	VERB
asodahs-29	322	75	a	a	DET
asodahs-29	322	76	rapid	rapid	ADJ
asodahs-29	322	77	and	and	CCONJ
asodahs-29	322	78	almost	almost	ADV
asodahs-29	322	79	complete	complete	ADJ
asodahs-29	322	80	release	release	NOUN
asodahs-29	322	81	of	of	ADP
asodahs-29	322	82	the	the	DET
asodahs-29	322	83	drug	drug	NOUN
asodahs-29	322	84	from	from	ADP
asodahs-29	322	85	their	their	PRON
asodahs-29	322	86	bases	basis	NOUN
asodahs-29	322	87	.	.	PUNCT
asodahs-29	323	1	rectal	rectal	ADJ
asodahs-29	323	2	administration	administration	NOUN
asodahs-29	323	3	of	of	ADP
asodahs-29	323	4	tramadol	tramadol	NOUN
asodahs-29	323	5	in	in	ADP
asodahs-29	323	6	addition	addition	NOUN
asodahs-29	323	7	to	to	ADP
asodahs-29	323	8	oral	oral	ADJ
asodahs-29	323	9	and	and	CCONJ
asodahs-29	323	10	intravenous	intravenous	ADJ
asodahs-29	323	11	administration	administration	NOUN
asodahs-29	323	12	may	may	AUX
asodahs-29	323	13	be	be	AUX
asodahs-29	323	14	an	an	DET
asodahs-29	323	15	alternative	alternative	ADJ
asodahs-29	323	16	route	route	NOUN
asodahs-29	323	17	for	for	ADP
asodahs-29	323	18	the	the	DET
asodahs-29	323	19	treatment	treatment	NOUN
asodahs-29	323	20	of	of	ADP
asodahs-29	323	21	pain	pain	NOUN
asodahs-29	323	22	.	.	PUNCT
asodahs-29	324	1	references	reference	NOUN
asodahs-29	324	2	1	1	NUM
asodahs-29	324	3	.	.	PUNCT
asodahs-29	324	4	goodman	goodman	PROPN
asodahs-29	324	5	do	do	VERB
asodahs-29	324	6	.	.	PUNCT
asodahs-29	325	1	pharmacokinetics	pharmacokinetic	NOUN
asodahs-29	325	2	:	:	PUNCT
asodahs-29	325	3	disposition	disposition	NOUN
asodahs-29	325	4	and	and	CCONJ
asodahs-29	325	5	metabolism	metabolism	NOUN
asodahs-29	325	6	of	of	ADP
asodahs-29	325	7	drugs	drug	NOUN
asodahs-29	325	8	.	.	PUNCT
asodahs-29	326	1	in	in	ADP
asodahs-29	326	2	:	:	PUNCT
asodahs-29	326	3	munson	munson	PROPN
asodahs-29	326	4	pl	pl	PROPN
asodahs-29	326	5	,	,	PUNCT
asodahs-29	326	6	muller	muller	PROPN
asodahs-29	326	7	ra	ra	PROPN
asodahs-29	326	8	,	,	PUNCT
asodahs-29	326	9	breese	breese	PROPN
asodahs-29	326	10	gr	gr	PROPN
asodahs-29	326	11	.	.	PUNCT
asodahs-29	326	12	editors	editor	NOUN
asodahs-29	326	13	.	.	PUNCT
asodahs-29	327	1	principles	principle	NOUN
asodahs-29	327	2	of	of	ADP
asodahs-29	327	3	pharmacology	pharmacology	NOUN
asodahs-29	327	4	,	,	PUNCT
asodahs-29	327	5	1st	1st	ADJ
asodahs-29	327	6	ed	ed	NOUN
asodahs-29	327	7	.	.	PUNCT
asodahs-29	328	1	new	new	PROPN
asodahs-29	328	2	york	york	PROPN
asodahs-29	328	3	:	:	PUNCT
asodahs-29	329	1	chapman	chapman	NOUN
asodahs-29	329	2	and	and	CCONJ
asodahs-29	329	3	hall	hall	PROPN
asodahs-29	329	4	;	;	PUNCT
asodahs-29	329	5	2001	2001	NUM
asodahs-29	329	6	.	.	PUNCT
asodahs-29	330	1	p.	p.	NOUN
asodahs-29	330	2	47	47	NUM
asodahs-29	330	3	.	.	PUNCT
asodahs-29	331	1	2	2	NUM
asodahs-29	331	2	.	.	NOUN
asodahs-29	331	3	sanyal	sanyal	PROPN
asodahs-29	331	4	p	p	NOUN
asodahs-29	331	5	,	,	PUNCT
asodahs-29	331	6	roy	roy	PROPN
asodahs-29	331	7	g.	g.	PROPN
asodahs-29	331	8	preparation	preparation	NOUN
asodahs-29	331	9	and	and	CCONJ
asodahs-29	331	10	evaluation	evaluation	NOUN
asodahs-29	331	11	of	of	ADP
asodahs-29	331	12	suppositories	suppository	NOUN
asodahs-29	331	13	of	of	ADP
asodahs-29	331	14	paracetamol	paracetamol	NOUN
asodahs-29	331	15	.	.	PUNCT
asodahs-29	332	1	east	east	PROPN
asodahs-29	332	2	pharma	pharma	PROPN
asodahs-29	332	3	2001	2001	NUM
asodahs-29	332	4	;	;	PUNCT
asodahs-29	332	5	49:95	49:95	NUM
asodahs-29	332	6	-	-	SYM
asodahs-29	332	7	7	7	NUM
asodahs-29	332	8	.	.	NOUN
asodahs-29	332	9	3	3	NUM
asodahs-29	332	10	.	.	X
asodahs-29	332	11	nair	nair	PROPN
asodahs-29	332	12	l	l	PROPN
asodahs-29	332	13	,	,	PUNCT
asodahs-29	332	14	bhargava	bhargava	PROPN
asodahs-29	332	15	hn	hn	PROPN
asodahs-29	332	16	.	.	PROPN
asodahs-29	332	17	comparison	comparison	NOUN
asodahs-29	332	18	of	of	ADP
asodahs-29	332	19	in	in	ADP
asodahs-29	332	20	vitro	vitro	X
asodahs-29	332	21	dissolution	dissolution	NOUN
asodahs-29	332	22	and	and	CCONJ
asodahs-29	332	23	permeation	permeation	NOUN
asodahs-29	332	24	of	of	ADP
asodahs-29	332	25	fluconazole	fluconazole	NOUN
asodahs-29	332	26	from	from	ADP
asodahs-29	332	27	different	different	ADJ
asodahs-29	332	28	suppository	suppository	ADJ
asodahs-29	332	29	bases	basis	NOUN
asodahs-29	332	30	.	.	PUNCT
asodahs-29	333	1	drug	drug	NOUN
asodahs-29	333	2	develop	develop	VERB
asodahs-29	333	3	ind	ind	NOUN
asodahs-29	333	4	pharm1999	pharm1999	NOUN
asodahs-29	333	5	;	;	PUNCT
asodahs-29	333	6	25:691	25:691	NUM
asodahs-29	333	7	-	-	SYM
asodahs-29	333	8	4	4	NUM
asodahs-29	333	9	.	.	PUNCT
asodahs-29	334	1	https://doi.org/10.1081/ddc-100102227	https://doi.org/10.1081/ddc-100102227	PROPN
asodahs-29	334	2	4	4	NUM
asodahs-29	334	3	.	.	PUNCT
asodahs-29	334	4	akala	akala	PROPN
asodahs-29	334	5	eo	eo	PROPN
asodahs-29	334	6	,	,	PUNCT
asodahs-29	334	7	adedoyn	adedoyn	VERB
asodahs-29	334	8	a	a	DET
asodahs-29	334	9	,	,	PUNCT
asodahs-29	334	10	ogunbona	ogunbona	INTJ
asodahs-29	334	11	fa	fa	PROPN
asodahs-29	334	12	.	.	PROPN
asodahs-29	334	13	suppository	suppository	PROPN
asodahs-29	334	14	formulations	formulation	NOUN
asodahs-29	334	15	of	of	ADP
asodahs-29	334	16	amodiaquine	amodiaquine	PROPN
asodahs-29	334	17	:	:	PUNCT
asodahs-29	334	18	in	in	ADP
asodahs-29	334	19	vitro	vitro	X
asodahs-29	334	20	release	release	NOUN
asodahs-29	334	21	characteristics	characteristic	NOUN
asodahs-29	334	22	.	.	PUNCT
asodahs-29	335	1	drug	drug	NOUN
asodahs-29	335	2	develop	develop	VERB
asodahs-29	335	3	ind	ind	NOUN
asodahs-29	335	4	pharm	pharm	NOUN
asodahs-29	335	5	1991	1991	NUM
asodahs-29	335	6	;	;	PUNCT
asodahs-29	335	7	17:303	17:303	NUM
asodahs-29	335	8	-	-	SYM
asodahs-29	335	9	7	7	NUM
asodahs-29	335	10	.	.	PUNCT
asodahs-29	336	1	https://doi.org/10.3109/03639049109043827	https://doi.org/10.3109/03639049109043827	NOUN
asodahs-29	336	2	5	5	NUM
asodahs-29	336	3	.	.	PUNCT
asodahs-29	336	4	kamlinder	kamlinder	PROPN
asodahs-29	336	5	ks	ks	PROPN
asodahs-29	336	6	,	,	PUNCT
asodahs-29	336	7	deshpande	deshpande	VERB
asodahs-29	336	8	sg	sg	PROPN
asodahs-29	336	9	,	,	PUNCT
asodahs-29	336	10	baichwal	baichwal	PROPN
asodahs-29	336	11	mr	mr	PROPN
asodahs-29	336	12	.	.	PROPN
asodahs-29	336	13	studies	study	NOUN
asodahs-29	336	14	on	on	ADP
asodahs-29	336	15	suppository	suppository	ADJ
asodahs-29	336	16	bases	basis	NOUN
asodahs-29	336	17	:	:	PUNCT
asodahs-29	336	18	design	design	NOUN
asodahs-29	336	19	and	and	CCONJ
asodahs-29	336	20	evaluation	evaluation	NOUN
asodahs-29	336	21	of	of	ADP
asodahs-29	336	22	sodium	sodium	NOUN
asodahs-29	336	23	cmc	cmc	NOUN
asodahs-29	336	24	and	and	CCONJ
asodahs-29	336	25	agar	agar	NOUN
asodahs-29	336	26	bases	basis	NOUN
asodahs-29	336	27	.	.	PUNCT
asodahs-29	337	1	indian	indian	ADJ
asodahs-29	337	2	drugs	drug	NOUN
asodahs-29	337	3	1994	1994	NUM
asodahs-29	337	4	;	;	PUNCT
asodahs-29	337	5	31:149	31:149	NUM
asodahs-29	337	6	-	-	SYM
asodahs-29	337	7	54	54	NUM
asodahs-29	337	8	.	.	PUNCT
asodahs-29	337	9	6	6	NUM
asodahs-29	337	10	.	.	X
asodahs-29	337	11	jayaprakash	jayaprakash	PROPN
asodahs-29	337	12	s	s	PROPN
asodahs-29	337	13	,	,	PUNCT
asodahs-29	337	14	jawahar	jawahar	PROPN
asodahs-29	337	15	n	n	PART
asodahs-29	337	16	,	,	PUNCT
asodahs-29	337	17	dhachina	dhachina	PROPN
asodahs-29	337	18	md	md	PROPN
asodahs-29	337	19	,	,	PUNCT
asodahs-29	337	20	ramkanth	ramkanth	PROPN
asodahs-29	337	21	s	s	PROPN
asodahs-29	337	22	,	,	PUNCT
asodahs-29	337	23	mohamed	mohamed	PROPN
asodahs-29	337	24	anzar	anzar	PROPN
asodahs-29	337	25	a	a	PRON
asodahs-29	337	26	,	,	PUNCT
asodahs-29	337	27	nagarajan	nagarajan	NOUN
asodahs-29	337	28	m.	m.	NOUN
asodahs-29	337	29	design	design	NOUN
asodahs-29	337	30	and	and	CCONJ
asodahs-29	337	31	evaluation	evaluation	NOUN
asodahs-29	337	32	of	of	ADP
asodahs-29	337	33	timed	time	VERB
asodahs-29	337	34	release	release	NOUN
asodahs-29	337	35	matrix	matrix	NOUN
asodahs-29	337	36	suppositories	suppository	NOUN
asodahs-29	337	37	of	of	ADP
asodahs-29	337	38	indomethacin	indomethacin	PROPN
asodahs-29	337	39	.	.	PUNCT
asodahs-29	338	1	pharm	pharm	PROPN
asodahs-29	338	2	rev	rev	VERB
asodahs-29	338	3	2006	2006	NUM
asodahs-29	338	4	;	;	PUNCT
asodahs-29	338	5	4:100	4:100	NUM
asodahs-29	338	6	-	-	SYM
asodahs-29	338	7	2	2	NUM
asodahs-29	338	8	.	.	NOUN
asodahs-29	338	9	7	7	NUM
asodahs-29	338	10	.	.	X
asodahs-29	338	11	dayer	dayer	PROPN
asodahs-29	338	12	p	p	NOUN
asodahs-29	338	13	,	,	PUNCT
asodahs-29	338	14	collart	collart	PROPN
asodahs-29	338	15	l	l	PROPN
asodahs-29	338	16	,	,	PUNCT
asodahs-29	338	17	desmeules	desmeule	VERB
asodahs-29	338	18	j.	j.	PROPN
asodahs-29	338	19	the	the	DET
asodahs-29	338	20	pharmacology	pharmacology	NOUN
asodahs-29	338	21	of	of	ADP
asodahs-29	338	22	tramadol	tramadol	NOUN
asodahs-29	338	23	.	.	PUNCT
asodahs-29	339	1	drugs	drug	NOUN
asodahs-29	339	2	.	.	PUNCT
asodahs-29	339	3	1994	1994	NUM
asodahs-29	339	4	;	;	PUNCT
asodahs-29	339	5	47(suppl):3	47(suppl):3	X
asodahs-29	339	6	-	-	SYM
asodahs-29	339	7	7	7	NUM
asodahs-29	339	8	.	.	PUNCT
asodahs-29	340	1	https://doi.org/10.2165/00003495199400471-00003	https://doi.org/10.2165/00003495199400471-00003	ADJ
asodahs-29	340	2	8	8	NUM
asodahs-29	340	3	.	.	PUNCT
asodahs-29	341	1	grond	grond	PROPN
asodahs-29	341	2	s	s	PROPN
asodahs-29	341	3	,	,	PUNCT
asodahs-29	341	4	sablotzki	sablotzki	VERB
asodahs-29	341	5	a.	a.	NOUN
asodahs-29	341	6	clinical	clinical	PROPN
asodahs-29	341	7	pharmacology	pharmacology	NOUN
asodahs-29	341	8	of	of	ADP
asodahs-29	341	9	tramadol	tramadol	NOUN
asodahs-29	341	10	.	.	PUNCT
asodahs-29	342	1	clin	clin	PROPN
asodahs-29	342	2	pharmacokinet	pharmacokinet	PROPN
asodahs-29	342	3	.	.	PUNCT
asodahs-29	342	4	2004	2004	NUM
asodahs-29	342	5	;	;	PUNCT
asodahs-29	342	6	43:879	43:879	NUM
asodahs-29	342	7	-	-	SYM
asodahs-29	342	8	923	923	NUM
asodahs-29	342	9	.	.	PUNCT
asodahs-29	343	1	https://doi.org/10.2165/00003088-200443130-00004	https://doi.org/10.2165/00003088-200443130-00004	VERB
asodahs-29	343	2	9	9	NUM
asodahs-29	343	3	.	.	PUNCT
asodahs-29	343	4	micromedex	micromedex	PROPN
asodahs-29	343	5	healthcare	healthcare	PROPN
asodahs-29	343	6	series	series	PROPN
asodahs-29	343	7	:	:	PUNCT
asodahs-29	343	8	document	document	NOUN
asodahs-29	343	9	2007	2007	NUM
asodahs-29	343	10	.	.	PUNCT
asodahs-29	344	1	tramadol	tramadol	NOUN
asodahs-29	344	2	.	.	PUNCT
asodahs-29	345	1	available	available	ADJ
asodahs-29	345	2	from	from	ADP
asodahs-29	345	3	:	:	PUNCT
asodahs-29	345	4	http://www.thomsonhc.com/	http://www.thomsonhc.com/	PROPN
asodahs-29	345	5	hcs	hcs	PROPN
asodahs-29	345	6	/	/	SYM
asodahs-29	345	7	librarian	librarian	PROPN
asodahs-29	345	8	/	/	SYM
asodahs-29	345	9	nd_pr	nd_pr	VERB
asodahs-29	345	10	/	/	SYM
asodahs-29	345	11	main	main	ADJ
asodahs-29	345	12	/	/	SYM
asodahs-29	345	13	sbk/3	sbk/3	NOUN
asodahs-29	345	14	/	/	SYM
asodahs-29	345	15	pfpui/7z16hw4	pfpui/7z16hw4	PROPN
asodahs-29	345	16	.	.	PROPN
asodahs-29	345	17	10	10	NUM
asodahs-29	345	18	.	.	PUNCT
asodahs-29	346	1	petrone	petrone	PROPN
asodahs-29	346	2	d	d	PROPN
asodahs-29	346	3	,	,	PUNCT
asodahs-29	346	4	kamin	kamin	PROPN
asodahs-29	346	5	m	m	PROPN
asodahs-29	346	6	,	,	PUNCT
asodahs-29	346	7	olson	olson	PROPN
asodahs-29	346	8	w.	w.	PROPN
asodahs-29	346	9	slowing	slow	VERB
asodahs-29	346	10	the	the	DET
asodahs-29	346	11	titration	titration	NOUN
asodahs-29	346	12	rate	rate	NOUN
asodahs-29	346	13	of	of	ADP
asodahs-29	346	14	tramadol	tramadol	NOUN
asodahs-29	346	15	hcl	hcl	PROPN
asodahs-29	346	16	reduces	reduce	VERB
asodahs-29	346	17	the	the	DET
asodahs-29	346	18	incidence	incidence	NOUN
asodahs-29	346	19	of	of	ADP
asodahs-29	346	20	discontinuation	discontinuation	NOUN
asodahs-29	346	21	due	due	ADP
asodahs-29	346	22	to	to	ADP
asodahs-29	346	23	nausea	nausea	NOUN
asodahs-29	346	24	and/	and/	NOUN
asodahs-29	346	25	or	or	CCONJ
asodahs-29	346	26	vomiting	vomiting	NOUN
asodahs-29	346	27	:	:	PUNCT
asodahs-29	346	28	a	a	DET
asodahs-29	346	29	double	double	ADJ
asodahs-29	346	30	-	-	PUNCT
asodahs-29	346	31	blind	blind	ADJ
asodahs-29	346	32	randomized	randomized	ADJ
asodahs-29	346	33	trial	trial	NOUN
asodahs-29	346	34	.	.	PUNCT
asodahs-29	347	1	j	j	PROPN
asodahs-29	347	2	clin	clin	PROPN
asodahs-29	347	3	pharm	pharm	PROPN
asodahs-29	347	4	ther	ther	ADV
asodahs-29	347	5	.	.	PUNCT
asodahs-29	348	1	1999	1999	NUM
asodahs-29	348	2	;	;	PUNCT
asodahs-29	348	3	24:115	24:115	NUM
asodahs-29	348	4	-	-	SYM
asodahs-29	348	5	23	23	NUM
asodahs-29	348	6	.	.	PUNCT
asodahs-29	349	1	https://doi.org/10.1046/j.13652710.1999.00203.x	https://doi.org/10.1046/j.13652710.1999.00203.x	X
asodahs-29	350	1	11	11	NUM
asodahs-29	350	2	.	.	PUNCT
asodahs-29	351	1	mercadante	mercadante	PROPN
asodahs-29	351	2	s	s	PROPN
asodahs-29	351	3	,	,	PUNCT
asodahs-29	351	4	arcuri	arcuri	PROPN
asodahs-29	351	5	e	e	PROPN
asodahs-29	351	6	,	,	PUNCT
asodahs-29	351	7	fusco	fusco	PROPN
asodahs-29	351	8	f	f	PROPN
asodahs-29	351	9	,	,	PUNCT
asodahs-29	351	10	tirelli	tirelli	PROPN
asodahs-29	351	11	w	w	PROPN
asodahs-29	351	12	,	,	PUNCT
asodahs-29	351	13	villari	villari	ADJ
asodahs-29	351	14	p	p	NOUN
asodahs-29	351	15	,	,	PUNCT
asodahs-29	351	16	bussolino	bussolino	PROPN
asodahs-29	351	17	c	c	PROPN
asodahs-29	351	18	,	,	PUNCT
asodahs-29	351	19	campa	campa	PROPN
asodahs-29	351	20	t	t	PROPN
asodahs-29	351	21	,	,	PUNCT
asodahs-29	351	22	de	de	X
asodahs-29	351	23	conno	conno	NOUN
asodahs-29	351	24	f	f	PROPN
asodahs-29	351	25	,	,	PUNCT
asodahs-29	351	26	ripamonti	ripamonti	PROPN
asodahs-29	351	27	c.	c.	PROPN
asodahs-29	351	28	randomized	randomize	VERB
asodahs-29	351	29	double	double	ADJ
asodahs-29	351	30	-	-	PUNCT
asodahs-29	351	31	blind	blind	ADJ
asodahs-29	351	32	,	,	PUNCT
asodahs-29	351	33	double	double	ADJ
asodahs-29	351	34	-	-	PUNCT
asodahs-29	351	35	dummy	dummy	NOUN
asodahs-29	351	36	crossover	crossover	ADP
asodahs-29	351	37	clinical	clinical	ADJ
asodahs-29	351	38	trial	trial	NOUN
asodahs-29	351	39	of	of	ADP
asodahs-29	351	40	oral	oral	ADJ
asodahs-29	351	41	tramadol	tramadol	NOUN
asodahs-29	351	42	versus	versus	ADP
asodahs-29	351	43	rectal	rectal	ADJ
asodahs-29	351	44	tramadol	tramadol	NOUN
asodahs-29	351	45	administration	administration	NOUN
asodahs-29	351	46	in	in	ADP
asodahs-29	351	47	opioid	opioid	ADJ
asodahs-29	351	48	-	-	PUNCT
asodahs-29	351	49	native	native	ADJ
asodahs-29	351	50	cancer	cancer	NOUN
asodahs-29	351	51	patients	patient	NOUN
asodahs-29	351	52	with	with	ADP
asodahs-29	351	53	pain	pain	NOUN
asodahs-29	351	54	.	.	PUNCT
asodahs-29	352	1	support	support	NOUN
asodahs-29	352	2	care	care	NOUN
asodahs-29	352	3	cancer	cancer	NOUN
asodahs-29	352	4	.	.	PUNCT
asodahs-29	353	1	2005	2005	NUM
asodahs-29	353	2	;	;	PUNCT
asodahs-29	353	3	13:702	13:702	NUM
asodahs-29	353	4	-	-	SYM
asodahs-29	353	5	7	7	NUM
asodahs-29	353	6	.	.	NUM
asodahs-29	354	1	https://doi.org/10.1007/s00520-004-0760-9	https://doi.org/10.1007/s00520-004-0760-9	NUM
asodahs-29	354	2	12	12	NUM
asodahs-29	354	3	.	.	PUNCT
asodahs-29	355	1	allen	allen	PROPN
asodahs-29	355	2	lv	lv	PROPN
asodahs-29	355	3	jr	jr	PROPN
asodahs-29	355	4	.	.	PUNCT
asodahs-29	355	5	compounding	compound	VERB
asodahs-29	355	6	suppositories	suppository	NOUN
asodahs-29	355	7	.	.	PUNCT
asodahs-29	356	1	part	part	NOUN
asodahs-29	357	1	i	i	NOUN
asodahs-29	357	2	:	:	PUNCT
asodahs-29	357	3	theoretical	theoretical	ADJ
asodahs-29	357	4	considerations	consideration	NOUN
asodahs-29	357	5	.	.	PUNCT
asodahs-29	358	1	int	int	NOUN
asodahs-29	358	2	j	j	PROPN
asodahs-29	358	3	pharm	pharm	PROPN
asodahs-29	358	4	compound	compound	PROPN
asodahs-29	358	5	.	.	PUNCT
asodahs-29	359	1	2000	2000	NUM
asodahs-29	359	2	;	;	PUNCT
asodahs-29	359	3	4:289	4:289	NUM
asodahs-29	359	4	-	-	SYM
asodahs-29	359	5	93	93	NUM
asodahs-29	359	6	.	.	PUNCT
asodahs-29	360	1	13	13	NUM
asodahs-29	360	2	.	.	X
asodahs-29	361	1	patel	patel	PROPN
asodahs-29	361	2	an	an	PROPN
asodahs-29	361	3	,	,	PUNCT
asodahs-29	361	4	rai	rai	PROPN
asodahs-29	361	5	jp	jp	PROPN
asodahs-29	361	6	,	,	PUNCT
asodahs-29	361	7	jain	jain	PROPN
asodahs-29	361	8	dk	dk	PROPN
asodahs-29	361	9	,	,	PUNCT
asodahs-29	361	10	banweer	banweer	PROPN
asodahs-29	361	11	ji	ji	PROPN
asodahs-29	361	12	.	.	PROPN
asodahs-29	361	13	formulation	formulation	PROPN
asodahs-29	361	14	,	,	PUNCT
asodahs-29	361	15	development	development	NOUN
asodahs-29	361	16	and	and	CCONJ
asodahs-29	361	17	evaluation	evaluation	NOUN
asodahs-29	361	18	of	of	ADP
asodahs-29	361	19	cefaclor	cefaclor	NOUN
asodahs-29	361	20	extended	extend	VERB
asodahs-29	361	21	release	release	NOUN
asodahs-29	361	22	matrix	matrix	NOUN
asodahs-29	361	23	tablet	tablet	NOUN
asodahs-29	361	24	.	.	PUNCT
asodahs-29	362	1	int	int	PROPN
asodahs-29	362	2	j	j	PROPN
asodahs-29	362	3	pharm	pharm	PROPN
asodahs-29	362	4	pharm	pharm	PROPN
asodahs-29	362	5	sci	sci	PROPN
asodahs-29	362	6	.	.	PROPN
asodahs-29	362	7	2012	2012	NUM
asodahs-29	362	8	;	;	PUNCT
asodahs-29	362	9	4(4):355	4(4):355	NUM
asodahs-29	362	10	-	-	SYM
asodahs-29	362	11	7	7	NUM
asodahs-29	362	12	.	.	NOUN
asodahs-29	362	13	14	14	NUM
asodahs-29	362	14	.	.	PUNCT
asodahs-29	363	1	jain	jain	PROPN
asodahs-29	363	2	p	p	PROPN
asodahs-29	363	3	,	,	PUNCT
asodahs-29	363	4	nair	nair	PROPN
asodahs-29	363	5	s	s	PROPN
asodahs-29	363	6	,	,	PUNCT
asodahs-29	363	7	jain	jain	PROPN
asodahs-29	363	8	n	n	CCONJ
asodahs-29	363	9	,	,	PUNCT
asodahs-29	363	10	jain	jain	PROPN
asodahs-29	363	11	dk	dk	PROPN
asodahs-29	363	12	,	,	PUNCT
asodahs-29	363	13	jain	jain	PROPN
asodahs-29	363	14	s.	s.	PROPN
asodahs-29	363	15	formulation	formulation	PROPN
asodahs-29	363	16	and	and	CCONJ
asodahs-29	363	17	evaluation	evaluation	NOUN
asodahs-29	363	18	of	of	ADP
asodahs-29	363	19	solid	solid	ADJ
asodahs-29	363	20	dispersion	dispersion	NOUN
asodahs-29	363	21	of	of	ADP
asodahs-29	363	22	lomefloxacin	lomefloxacin	PROPN
asodahs-29	363	23	hydrochloride	hydrochloride	NOUN
asodahs-29	363	24	.	.	PUNCT
asodahs-29	364	1	int	int	PROPN
asodahs-29	364	2	j	j	PROPN
asodahs-29	364	3	res	res	PROPN
asodahs-29	364	4	pharm	pharm	NOUN
asodahs-29	364	5	sci	sci	PROPN
asodahs-29	364	6	2012	2012	NUM
asodahs-29	364	7	;	;	PUNCT
asodahs-29	364	8	3(4):604	3(4):604	NUM
asodahs-29	364	9	-	-	SYM
asodahs-29	364	10	608	608	NUM
asodahs-29	364	11	.	.	PUNCT
asodahs-29	364	12	15	15	NUM
asodahs-29	364	13	.	.	X
asodahs-29	364	14	block	block	PROPN
asodahs-29	364	15	lh	lh	PROPN
asodahs-29	364	16	.	.	PUNCT
asodahs-29	365	1	medicated	medicate	VERB
asodahs-29	365	2	topicals	topical	NOUN
asodahs-29	365	3	.	.	PUNCT
asodahs-29	366	1	in	in	ADP
asodahs-29	366	2	:	:	PUNCT
asodahs-29	366	3	gennaro	gennaro	PROPN
asodahs-29	366	4	ar	ar	PROPN
asodahs-29	366	5	.	.	PROPN
asodahs-29	366	6	editors	editor	NOUN
asodahs-29	366	7	.	.	PUNCT
asodahs-29	367	1	remington	remington	NOUN
asodahs-29	367	2	:	:	PUNCT
asodahs-29	367	3	the	the	DET
asodahs-29	367	4	science	science	NOUN
asodahs-29	367	5	and	and	CCONJ
asodahs-29	367	6	practice	practice	NOUN
asodahs-29	367	7	of	of	ADP
asodahs-29	367	8	pharmacy	pharmacy	NOUN
asodahs-29	367	9	.	.	PUNCT
asodahs-29	368	1	21st	21st	ADJ
asodahs-29	368	2	ed	ed	NOUN
asodahs-29	368	3	.	.	PUNCT
asodahs-29	368	4	vol	vol	NOUN
asodahs-29	368	5	.	.	PROPN
asodahs-29	369	1	2	2	NUM
asodahs-29	369	2	.	.	X
asodahs-29	369	3	noida	noida	PROPN
asodahs-29	369	4	:	:	PUNCT
asodahs-29	369	5	lippincott	lippincott	PROPN
asodahs-29	369	6	williams	williams	PROPN
asodahs-29	369	7	and	and	CCONJ
asodahs-29	369	8	wilkins	wilkin	NOUN
asodahs-29	369	9	;	;	PUNCT
asodahs-29	369	10	2005	2005	NUM
asodahs-29	369	11	.	.	PUNCT
asodahs-29	370	1	p.	p.	NOUN
asodahs-29	370	2	885	885	NUM
asodahs-29	370	3	-	-	SYM
asodahs-29	370	4	6	6	NUM
asodahs-29	370	5	.	.	NOUN
asodahs-29	370	6	16	16	NUM
asodahs-29	370	7	.	.	PUNCT
asodahs-29	371	1	british	british	ADJ
asodahs-29	371	2	pharmacopoieal	pharmacopoieal	PROPN
asodahs-29	371	3	convention	convention	PROPN
asodahs-29	371	4	.	.	PUNCT
asodahs-29	372	1	british	british	ADJ
asodahs-29	372	2	pharmacopoeia	pharmacopoeia	PROPN
asodahs-29	372	3	.	.	PUNCT
asodahs-29	373	1	vol	vol	NOUN
asodahs-29	373	2	.	.	PROPN
asodahs-29	374	1	2	2	NUM
asodahs-29	374	2	.	.	X
asodahs-29	374	3	london	london	PROPN
asodahs-29	374	4	:	:	PUNCT
asodahs-29	374	5	h.m	h.m	PROPN
asodahs-29	374	6	stationery	stationery	NOUN
asodahs-29	374	7	offi	offi	PROPN
asodahs-29	374	8	ce	ce	PROPN
asodahs-29	374	9	;	;	PUNCT
asodahs-29	374	10	1993	1993	NUM
asodahs-29	374	11	.	.	PUNCT
asodahs-29	375	1	17	17	NUM
asodahs-29	375	2	.	.	PUNCT
asodahs-29	376	1	coben	coben	PROPN
asodahs-29	376	2	lj	lj	PROPN
asodahs-29	376	3	,	,	PUNCT
asodahs-29	376	4	liberman	liberman	PROPN
asodahs-29	376	5	ha	ha	INTJ
asodahs-29	376	6	.	.	PROPN
asodahs-29	376	7	suppositories	suppository	NOUN
asodahs-29	376	8	.	.	PUNCT
asodahs-29	377	1	in	in	ADP
asodahs-29	377	2	:	:	PUNCT
asodahs-29	377	3	lachman	lachman	PROPN
asodahs-29	377	4	l	l	PROPN
asodahs-29	377	5	,	,	PUNCT
asodahs-29	377	6	liberman	liberman	PROPN
asodahs-29	377	7	ha	ha	INTJ
asodahs-29	377	8	,	,	PUNCT
asodahs-29	377	9	kanig	kanig	PROPN
asodahs-29	377	10	jl	jl	PROPN
asodahs-29	377	11	,	,	PUNCT
asodahs-29	377	12	editors	editor	NOUN
asodahs-29	377	13	.	.	PUNCT
asodahs-29	378	1	theory	theory	NOUN
asodahs-29	378	2	and	and	CCONJ
asodahs-29	378	3	practice	practice	NOUN
asodahs-29	378	4	of	of	ADP
asodahs-29	378	5	industrial	industrial	ADJ
asodahs-29	378	6	pharmacy	pharmacy	NOUN
asodahs-29	378	7	.	.	PUNCT
asodahs-29	379	1	3rd	3rd	ADJ
asodahs-29	379	2	ed	ed	NOUN
asodahs-29	379	3	.	.	PUNCT
asodahs-29	379	4	mumbai	mumbai	PROPN
asodahs-29	379	5	:	:	PUNCT
asodahs-29	380	1	varghese	varghese	PROPN
asodahs-29	380	2	publishing	publishing	PROPN
asodahs-29	380	3	house	house	PROPN
asodahs-29	380	4	;	;	PUNCT
asodahs-29	380	5	1989	1989	NUM
asodahs-29	380	6	.	.	PUNCT
asodahs-29	381	1	p.	p.	NOUN
asodahs-29	381	2	580	580	NUM
asodahs-29	381	3	.	.	PUNCT
asodahs-29	382	1	18	18	NUM
asodahs-29	382	2	.	.	PUNCT
asodahs-29	383	1	senthil	senthil	PROPN
asodahs-29	383	2	kumaran	kumaran	PROPN
asodahs-29	383	3	k	k	PROPN
asodahs-29	383	4	,	,	PUNCT
asodahs-29	383	5	thiruganasambantham	thiruganasambantham	PROPN
asodahs-29	383	6	p	p	X
asodahs-29	383	7	,	,	PUNCT
asodahs-29	383	8	viswanathan	viswanathan	PROPN
asodahs-29	383	9	s	s	PROPN
asodahs-29	383	10	,	,	PUNCT
asodahs-29	383	11	shree	shree	PROPN
asodahs-29	383	12	rammurthy	rammurthy	ADJ
asodahs-29	383	13	m.	m.	NOUN
asodahs-29	383	14	development	development	NOUN
asodahs-29	383	15	and	and	CCONJ
asodahs-29	383	16	evaluation	evaluation	NOUN
asodahs-29	383	17	of	of	ADP
asodahs-29	383	18	andrographolide	andrographolide	ADJ
asodahs-29	383	19	(	(	PUNCT
asodahs-29	383	20	from	from	ADP
asodahs-29	383	21	andrographis	andrographis	PRON
asodahs-29	383	22	paniculata	paniculata	ADJ
asodahs-29	383	23	)	)	PUNCT
asodahs-29	383	24	rectal	rectal	ADJ
asodahs-29	383	25	suppositories	suppository	NOUN
asodahs-29	383	26	.	.	PUNCT
asodahs-29	384	1	indian	indian	ADJ
asodahs-29	384	2	drugs	drug	NOUN
asodahs-29	384	3	2002	2002	NUM
asodahs-29	384	4	;	;	PUNCT
asodahs-29	384	5	39:648	39:648	NUM
asodahs-29	384	6	-	-	SYM
asodahs-29	384	7	51	51	NUM
asodahs-29	384	8	.	.	NOUN
asodahs-29	384	9	19	19	NUM
asodahs-29	384	10	.	.	X
asodahs-29	384	11	hammouda	hammouda	PROPN
asodahs-29	384	12	ye	ye	PROPN
asodahs-29	384	13	,	,	PUNCT
asodahs-29	384	14	kasim	kasim	PROPN
asodahs-29	384	15	na	na	PROPN
asodahs-29	384	16	,	,	PUNCT
asodahs-29	384	17	nada	nada	PROPN
asodahs-29	384	18	ah	ah	INTJ
asodahs-29	384	19	.	.	PUNCT
asodahs-29	385	1	formulation	formulation	NOUN
asodahs-29	385	2	and	and	CCONJ
asodahs-29	385	3	in	in	ADP
asodahs-29	385	4	vitro	vitro	X
asodahs-29	385	5	evaluation	evaluation	NOUN
asodahs-29	385	6	of	of	ADP
asodahs-29	385	7	verapamil	verapamil	NOUN
asodahs-29	385	8	hcl	hcl	PROPN
asodahs-29	385	9	suppositories	suppository	NOUN
asodahs-29	385	10	.	.	PUNCT
asodahs-29	386	1	int	int	NOUN
asodahs-29	386	2	j	j	PROPN
asodahs-29	386	3	pharm	pharm	PROPN
asodahs-29	386	4	1993	1993	NUM
asodahs-29	386	5	;	;	PUNCT
asodahs-29	386	6	89:111	89:111	NUM
asodahs-29	386	7	-	-	SYM
asodahs-29	386	8	117	117	NUM
asodahs-29	386	9	.	.	PUNCT
asodahs-29	387	1	https://doi.org/10.1016/0378-5173(93)90111-r	https://doi.org/10.1016/0378-5173(93)90111-r	NOUN
asodahs-29	387	2	https://doi.org/10.1081/ddc-100102227	https://doi.org/10.1081/ddc-100102227	X
asodahs-29	387	3	https://doi.org/10.3109/03639049109043827	https://doi.org/10.3109/03639049109043827	X
asodahs-29	387	4	https://doi.org/10.2165/00003495-199400471-00003	https://doi.org/10.2165/00003495-199400471-00003	NOUN
asodahs-29	387	5	https://doi.org/10.2165/00003495-199400471-00003	https://doi.org/10.2165/00003495-199400471-00003	X
asodahs-29	387	6	https://doi.org/10.2165/00003088-200443130-00004	https://doi.org/10.2165/00003088-200443130-00004	X
asodahs-29	387	7	https://doi.org/10.1046/j.1365-2710.1999.00203.x	https://doi.org/10.1046/j.1365-2710.1999.00203.x	X
asodahs-29	387	8	https://doi.org/10.1046/j.1365-2710.1999.00203.x	https://doi.org/10.1046/j.1365-2710.1999.00203.x	ADP
asodahs-29	387	9	https://doi.org/10.1007/s00520-004-0760-9	https://doi.org/10.1007/s00520-004-0760-9	NUM
asodahs-29	387	10	https://doi.org/10.1016/0378-5173(93)90111-r	https://doi.org/10.1016/0378-5173(93)90111-r	NOUN