id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
aji-174	Ajibola, Fagbemi Oluwaseyi; Ayodele, Adedoyin Elizabeth	Epigenetic Dysregulation and its Role in Immune-Mediated Diseases	2025	12	.pdf	application/pdf	6870	480	40	These studies have robustly confirmed the paramount importance of the major histocompatibility complex (MHC) region and highlighted key pathways involved in immune cell signaling, cytokine production, and lymphocyte activation (Ausserwinkler et al., 2025; Arneth, 2024). These factors can initiate stable epigenetic reprogramming within immune cells, potentially leading to the sustained overexpression of pro- inflammatory genes or the silencing of key immunoregulatory pathways.	cache/aji-174.pdf	txt/aji-174.txt