id	sid	tid	token	lemma	pos
aji-171	1	1	_	_	PUNCT
aji-171	2	1	_	_	PUNCT
aji-171	3	1	_	_	PUNCT
aji-171	4	1	_	_	PUNCT
aji-171	5	1	_	_	PUNCT
aji-171	6	1	_	_	PUNCT
aji-171	7	1	_	_	PUNCT
aji-171	8	1	_	_	PUNCT
aji-171	9	1	_	_	PUNCT
aji-171	10	1	_	_	PUNCT
aji-171	11	1	_	_	PUNCT
aji-171	12	1	_	_	PUNCT
aji-171	13	1	_	_	PUNCT
aji-171	14	1	_	_	PUNCT
aji-171	15	1	_	_	PUNCT
aji-171	16	1	_	_	PUNCT
aji-171	17	1	_	_	PUNCT
aji-171	18	1	_	_	PUNCT
aji-171	19	1	_	_	PUNCT
aji-171	20	1	_	_	PUNCT
aji-171	21	1	_	_	PUNCT
aji-171	22	1	_	_	PUNCT
aji-171	23	1	_	_	PUNCT
aji-171	24	1	_	_	PUNCT
aji-171	25	1	_	_	PUNCT
aji-171	26	1	_	_	PUNCT
aji-171	27	1	_	_	PUNCT
aji-171	28	1	_	_	PUNCT
aji-171	29	1	_	_	PUNCT
aji-171	30	1	_	_	PUNCT
aji-171	31	1	_	_	PUNCT
aji-171	32	1	_	_	PUNCT
aji-171	33	1	_	_	PUNCT
aji-171	34	1	_	_	PUNCT
aji-171	35	1	_	_	PUNCT
aji-171	36	1	_	_	PUNCT
aji-171	37	1	_	_	PUNCT
aji-171	38	1	_	_	PUNCT
aji-171	39	1	_	_	PUNCT
aji-171	40	1	_	_	PUNCT
aji-171	41	1	_	_	PUNCT
aji-171	42	1	_	_	PUNCT
aji-171	43	1	_	_	PUNCT
aji-171	44	1	_	_	PUNCT
aji-171	45	1	_	_	PUNCT
aji-171	46	1	_	_	PUNCT
aji-171	47	1	_	_	PUNCT
aji-171	48	1	_	_	PUNCT
aji-171	49	1	_	_	PUNCT
aji-171	50	1	_	_	PUNCT
aji-171	51	1	_	_	PUNCT
aji-171	52	1	_	_	PUNCT
aji-171	53	1	_	_	PUNCT
aji-171	54	1	_	_	PUNCT
aji-171	55	1	_	_	PUNCT
aji-171	56	1	_	_	PUNCT
aji-171	57	1	_	_	PUNCT
aji-171	58	1	_	_	PUNCT
aji-171	59	1	_	_	PUNCT
aji-171	60	1	_	_	PUNCT
aji-171	61	1	_	_	PUNCT
aji-171	62	1	_	_	PUNCT
aji-171	63	1	_	_	PUNCT
aji-171	64	1	_	_	PUNCT
aji-171	65	1	_	_	PUNCT
aji-171	66	1	_	_	PUNCT
aji-171	67	1	_	_	PUNCT
aji-171	68	1	_	_	PUNCT
aji-171	69	1	_	_	PUNCT
aji-171	70	1	_	_	PUNCT
aji-171	71	1	_	_	PUNCT
aji-171	72	1	_	_	PUNCT
aji-171	73	1	_	_	PUNCT
aji-171	74	1	_	_	PUNCT
aji-171	75	1	_	_	PUNCT
aji-171	76	1	_	_	PUNCT
aji-171	77	1	_	_	PUNCT
aji-171	78	1	_	_	PUNCT
aji-171	79	1	_	_	PUNCT
aji-171	80	1	_	_	PUNCT
aji-171	81	1	_	_	PUNCT
aji-171	82	1	_	_	PUNCT
aji-171	83	1	_	_	PUNCT
aji-171	84	1	_	_	PUNCT
aji-171	85	1	_	_	PUNCT
aji-171	86	1	_	_	PUNCT
aji-171	87	1	_	_	PUNCT
aji-171	88	1	_	_	PUNCT
aji-171	89	1	_	_	PUNCT
aji-171	90	1	_	_	PUNCT
aji-171	91	1	_	_	PUNCT
aji-171	92	1	_	_	PUNCT
aji-171	93	1	_	_	PUNCT
aji-171	94	1	_	_	PUNCT
aji-171	95	1	_	_	PUNCT
aji-171	96	1	_	_	PUNCT
aji-171	97	1	_	_	PUNCT
aji-171	98	1	_	_	PUNCT
aji-171	99	1	_	_	PUNCT
aji-171	100	1	_	_	PUNCT
aji-171	101	1	_	_	PUNCT
aji-171	102	1	*	*	PUNCT
aji-171	102	2	corresponding	correspond	VERB
aji-171	102	3	author	author	NOUN
aji-171	102	4	:	:	PUNCT
aji-171	102	5	e	e	NOUN
aji-171	102	6	-	-	NOUN
aji-171	102	7	mail	mail	NOUN
aji-171	102	8	:	:	PUNCT
aji-171	102	9	calebangulu1@gmail.com	calebangulu1@gmail.com	NUM
aji-171	102	10	;	;	PUNCT
aji-171	102	11	cite	cite	VERB
aji-171	102	12	as	as	ADP
aji-171	102	13	:	:	PUNCT
aji-171	102	14	mamman	mamman	NOUN
aji-171	102	15	,	,	PUNCT
aji-171	102	16	godiya	godiya	PROPN
aji-171	102	17	peter	peter	PROPN
aji-171	102	18	,	,	PUNCT
aji-171	102	19	caleb	caleb	PROPN
aji-171	102	20	ndako	ndako	PROPN
aji-171	102	21	angulu	angulu	PROPN
aji-171	102	22	,	,	PUNCT
aji-171	102	23	aminu	aminu	PROPN
aji-171	102	24	,	,	PUNCT
aji-171	102	25	ado	ado	PROPN
aji-171	102	26	,	,	PUNCT
aji-171	102	27	mohammed	mohammed	PROPN
aji-171	102	28	evuti	evuti	PROPN
aji-171	102	29	mahmud	mahmud	PROPN
aji-171	102	30	,	,	PUNCT
aji-171	102	31	ruqayyatu	ruqayyatu	NOUN
aji-171	102	32	aliyu	aliyu	NOUN
aji-171	102	33	,	,	PUNCT
aji-171	102	34	samuel	samuel	PROPN
aji-171	102	35	angulu	angulu	VERB
aji-171	102	36	,	,	PUNCT
aji-171	102	37	and	and	CCONJ
aji-171	102	38	adeoye	adeoye	VERB
aji-171	102	39	daniel	daniel	PROPN
aji-171	102	40	owoyale	owoyale	PROPN
aji-171	102	41	.	.	PUNCT
aji-171	103	1	2025	2025	NUM
aji-171	103	2	.	.	PUNCT
aji-171	104	1	“	"	PUNCT
aji-171	104	2	metabolomics	metabolomic	NOUN
aji-171	104	3	role	role	NOUN
aji-171	104	4	in	in	ADP
aji-171	104	5	health	health	NOUN
aji-171	104	6	and	and	CCONJ
aji-171	104	7	disease	disease	NOUN
aji-171	104	8	:	:	PUNCT
aji-171	104	9	current	current	ADJ
aji-171	104	10	status	status	NOUN
aji-171	104	11	and	and	CCONJ
aji-171	104	12	future	future	ADJ
aji-171	104	13	directions	direction	NOUN
aji-171	104	14	”	"	PUNCT
aji-171	104	15	.	.	PUNCT
aji-171	105	1	asian	asian	ADJ
aji-171	105	2	journal	journal	NOUN
aji-171	105	3	of	of	ADP
aji-171	105	4	immunology	immunology	NOUN
aji-171	105	5	8	8	NUM
aji-171	105	6	(	(	PUNCT
aji-171	105	7	1):190	1):190	NUM
aji-171	105	8	-	-	PUNCT
aji-171	105	9	206	206	NUM
aji-171	105	10	.	.	PUNCT
aji-171	106	1	https://doi.org/10.9734/aji/2025/v8i1171	https://doi.org/10.9734/aji/2025/v8i1171	PROPN
aji-171	106	2	.	.	PUNCT
aji-171	107	1	asian	asian	PROPN
aji-171	107	2	journal	journal	PROPN
aji-171	107	3	of	of	ADP
aji-171	107	4	immunology	immunology	NOUN
aji-171	107	5	volume	volume	NOUN
aji-171	107	6	8	8	NUM
aji-171	107	7	,	,	PUNCT
aji-171	107	8	issue	issue	NOUN
aji-171	107	9	1	1	NUM
aji-171	107	10	,	,	PUNCT
aji-171	107	11	page	page	NOUN
aji-171	107	12	190	190	NUM
aji-171	107	13	-	-	SYM
aji-171	107	14	206	206	NUM
aji-171	107	15	,	,	PUNCT
aji-171	107	16	2025	2025	NUM
aji-171	107	17	;	;	PUNCT
aji-171	107	18	article	article	NOUN
aji-171	107	19	no.aji.140476	no.aji.140476	NOUN
aji-171	107	20	metabolomics	metabolomic	NOUN
aji-171	107	21	role	role	NOUN
aji-171	107	22	in	in	ADP
aji-171	107	23	health	health	NOUN
aji-171	107	24	and	and	CCONJ
aji-171	107	25	disease	disease	NOUN
aji-171	107	26	:	:	PUNCT
aji-171	107	27	current	current	ADJ
aji-171	107	28	status	status	NOUN
aji-171	107	29	and	and	CCONJ
aji-171	107	30	future	future	ADJ
aji-171	107	31	directions	direction	NOUN
aji-171	107	32	godiya	godiya	PROPN
aji-171	107	33	peter	peter	PROPN
aji-171	107	34	mamman	mamman	PROPN
aji-171	107	35	a	a	PROPN
aji-171	107	36	,	,	PUNCT
aji-171	107	37	caleb	caleb	PROPN
aji-171	107	38	ndako	ndako	PROPN
aji-171	107	39	angulu	angulu	VERB
aji-171	107	40	b	b	PROPN
aji-171	107	41	*	*	PROPN
aji-171	107	42	,	,	PUNCT
aji-171	107	43	aminu	aminu	PROPN
aji-171	107	44	,	,	PUNCT
aji-171	107	45	ado	ado	PROPN
aji-171	107	46	b	b	PROPN
aji-171	107	47	,	,	PUNCT
aji-171	107	48	mohammed	mohammed	PROPN
aji-171	107	49	evuti	evuti	PROPN
aji-171	107	50	mahmud	mahmud	PROPN
aji-171	107	51	c	c	X
aji-171	107	52	,	,	PUNCT
aji-171	107	53	ruqayyatu	ruqayyatu	PROPN
aji-171	107	54	aliyu	aliyu	NOUN
aji-171	107	55	a	a	PRON
aji-171	107	56	,	,	PUNCT
aji-171	107	57	samuel	samuel	PROPN
aji-171	107	58	angulu	angulu	VERB
aji-171	107	59	d	d	PROPN
aji-171	107	60	and	and	CCONJ
aji-171	107	61	adeoye	adeoye	VERB
aji-171	107	62	daniel	daniel	PROPN
aji-171	107	63	owoyale	owoyale	PROPN
aji-171	107	64	e	e	PROPN
aji-171	107	65	a	a	DET
aji-171	107	66	department	department	NOUN
aji-171	107	67	of	of	ADP
aji-171	107	68	biology	biology	NOUN
aji-171	107	69	nigeria	nigeria	PROPN
aji-171	107	70	army	army	PROPN
aji-171	107	71	university	university	PROPN
aji-171	107	72	,	,	PUNCT
aji-171	107	73	biu	biu	PROPN
aji-171	107	74	born	bear	VERB
aji-171	107	75	state	state	NOUN
aji-171	107	76	,	,	PUNCT
aji-171	107	77	nigeria	nigeria	PROPN
aji-171	107	78	.	.	PUNCT
aji-171	108	1	b	b	X
aji-171	108	2	department	department	NOUN
aji-171	108	3	of	of	ADP
aji-171	108	4	microbiology	microbiology	NOUN
aji-171	108	5	,	,	PUNCT
aji-171	108	6	federal	federal	ADJ
aji-171	108	7	university	university	NOUN
aji-171	108	8	dutsin	dutsin	PROPN
aji-171	108	9	-	-	PUNCT
aji-171	108	10	ma	ma	PROPN
aji-171	108	11	katsina	katsina	PROPN
aji-171	108	12	state	state	PROPN
aji-171	108	13	,	,	PUNCT
aji-171	108	14	nigeria	nigeria	PROPN
aji-171	108	15	.	.	PUNCT
aji-171	109	1	c	c	PROPN
aji-171	109	2	department	department	PROPN
aji-171	109	3	of	of	ADP
aji-171	109	4	natural	natural	ADJ
aji-171	109	5	and	and	CCONJ
aji-171	109	6	applied	applied	ADJ
aji-171	109	7	sciences	science	NOUN
aji-171	109	8	,	,	PUNCT
aji-171	109	9	college	college	NOUN
aji-171	109	10	of	of	ADP
aji-171	109	11	nursing	nursing	NOUN
aji-171	109	12	sciences	science	NOUN
aji-171	109	13	,	,	PUNCT
aji-171	109	14	bida	bida	PROPN
aji-171	109	15	,	,	PUNCT
aji-171	109	16	niger	niger	NOUN
aji-171	109	17	state	state	NOUN
aji-171	109	18	,	,	PUNCT
aji-171	109	19	nigeria	nigeria	PROPN
aji-171	109	20	.	.	PUNCT
aji-171	110	1	d	d	DET
aji-171	110	2	department	department	NOUN
aji-171	110	3	of	of	ADP
aji-171	110	4	basic	basic	ADJ
aji-171	110	5	and	and	CCONJ
aji-171	110	6	natural	natural	ADJ
aji-171	110	7	sciences	science	NOUN
aji-171	110	8	,	,	PUNCT
aji-171	110	9	niger	niger	NOUN
aji-171	110	10	state	state	NOUN
aji-171	110	11	,	,	PUNCT
aji-171	110	12	college	college	NOUN
aji-171	110	13	of	of	ADP
aji-171	110	14	agriculture	agriculture	PROPN
aji-171	110	15	mokwa	mokwa	PROPN
aji-171	110	16	,	,	PUNCT
aji-171	110	17	niger	niger	NOUN
aji-171	110	18	state	state	NOUN
aji-171	110	19	,	,	PUNCT
aji-171	110	20	nigeria	nigeria	PROPN
aji-171	110	21	.	.	PUNCT
aji-171	111	1	e	e	X
aji-171	111	2	school	school	NOUN
aji-171	111	3	of	of	ADP
aji-171	111	4	life	life	NOUN
aji-171	111	5	sciences	sciences	PROPN
aji-171	111	6	,	,	PUNCT
aji-171	111	7	department	department	NOUN
aji-171	111	8	of	of	ADP
aji-171	111	9	microbiology	microbiology	NOUN
aji-171	111	10	,	,	PUNCT
aji-171	111	11	federal	federal	ADJ
aji-171	111	12	university	university	PROPN
aji-171	111	13	of	of	ADP
aji-171	111	14	technology	technology	NOUN
aji-171	111	15	,	,	PUNCT
aji-171	111	16	minna	minna	NOUN
aji-171	111	17	,	,	PUNCT
aji-171	111	18	niger	niger	NOUN
aji-171	111	19	state	state	NOUN
aji-171	111	20	,	,	PUNCT
aji-171	111	21	nigeria	nigeria	PROPN
aji-171	111	22	.	.	PUNCT
aji-171	112	1	authors	author	NOUN
aji-171	112	2	’	'	PUNCT
aji-171	112	3	contributions	contribution	NOUN
aji-171	112	4	this	this	DET
aji-171	112	5	work	work	NOUN
aji-171	112	6	was	be	AUX
aji-171	112	7	carried	carry	VERB
aji-171	112	8	out	out	ADP
aji-171	112	9	in	in	ADP
aji-171	112	10	collaboration	collaboration	NOUN
aji-171	112	11	among	among	ADP
aji-171	112	12	all	all	DET
aji-171	112	13	authors	author	NOUN
aji-171	112	14	.	.	PUNCT
aji-171	113	1	all	all	DET
aji-171	113	2	authors	author	NOUN
aji-171	113	3	read	read	VERB
aji-171	113	4	and	and	CCONJ
aji-171	113	5	approved	approve	VERB
aji-171	113	6	the	the	DET
aji-171	113	7	final	final	ADJ
aji-171	113	8	manuscript	manuscript	NOUN
aji-171	113	9	.	.	PUNCT
aji-171	114	1	article	article	NOUN
aji-171	114	2	information	information	PROPN
aji-171	114	3	doi	doi	PROPN
aji-171	114	4	:	:	PUNCT
aji-171	114	5	https://doi.org/10.9734/aji/2025/v8i1171	https://doi.org/10.9734/aji/2025/v8i1171	PROPN
aji-171	114	6	open	open	ADJ
aji-171	114	7	peer	peer	NOUN
aji-171	114	8	review	review	NOUN
aji-171	114	9	history	history	NOUN
aji-171	114	10	:	:	PUNCT
aji-171	114	11	this	this	DET
aji-171	114	12	journal	journal	NOUN
aji-171	114	13	follows	follow	VERB
aji-171	114	14	the	the	DET
aji-171	114	15	advanced	advance	VERB
aji-171	114	16	open	open	ADJ
aji-171	114	17	peer	peer	NOUN
aji-171	114	18	review	review	NOUN
aji-171	114	19	policy	policy	NOUN
aji-171	114	20	.	.	PUNCT
aji-171	115	1	identity	identity	NOUN
aji-171	115	2	of	of	ADP
aji-171	115	3	the	the	DET
aji-171	115	4	reviewers	reviewer	NOUN
aji-171	115	5	,	,	PUNCT
aji-171	115	6	editor(s	editor(s	NOUN
aji-171	115	7	)	)	PUNCT
aji-171	115	8	and	and	CCONJ
aji-171	115	9	additional	additional	ADJ
aji-171	115	10	reviewers	reviewer	NOUN
aji-171	115	11	,	,	PUNCT
aji-171	115	12	peer	peer	NOUN
aji-171	115	13	review	review	NOUN
aji-171	115	14	comments	comment	NOUN
aji-171	115	15	,	,	PUNCT
aji-171	115	16	different	different	ADJ
aji-171	115	17	versions	version	NOUN
aji-171	115	18	of	of	ADP
aji-171	115	19	the	the	DET
aji-171	115	20	manuscript	manuscript	NOUN
aji-171	115	21	,	,	PUNCT
aji-171	115	22	comments	comment	NOUN
aji-171	115	23	of	of	ADP
aji-171	115	24	the	the	DET
aji-171	115	25	editors	editor	NOUN
aji-171	115	26	,	,	PUNCT
aji-171	115	27	etc	etc	X
aji-171	115	28	are	be	AUX
aji-171	115	29	available	available	ADJ
aji-171	115	30	here	here	ADV
aji-171	115	31	:	:	PUNCT
aji-171	115	32	https://pr.sdiarticle5.com/review-history/140476	https://pr.sdiarticle5.com/review-history/140476	NUM
aji-171	115	33	received	receive	VERB
aji-171	115	34	:	:	PUNCT
aji-171	115	35	01/06/2025	01/06/2025	NUM
aji-171	115	36	published	publish	VERB
aji-171	115	37	:	:	PUNCT
aji-171	115	38	29/07/2025	29/07/2025	NUM
aji-171	115	39	review	review	NOUN
aji-171	115	40	article	article	NOUN
aji-171	115	41	https://doi.org/10.9734/aji/2025/v8i1171	https://doi.org/10.9734/aji/2025/v8i1171	PROPN
aji-171	115	42	https://pr.sdiarticle5.com/review-history/140476	https://pr.sdiarticle5.com/review-history/140476	PROPN
aji-171	115	43	mamman	mamman	NOUN
aji-171	115	44	et	et	PROPN
aji-171	115	45	al	al	PROPN
aji-171	115	46	.	.	PROPN
aji-171	115	47	;	;	PUNCT
aji-171	115	48	asian	asian	PROPN
aji-171	115	49	j.	j.	PROPN
aji-171	115	50	immunol	immunol	PROPN
aji-171	115	51	.	.	PROPN
aji-171	115	52	,	,	PUNCT
aji-171	115	53	vol	vol	NOUN
aji-171	115	54	.	.	PROPN
aji-171	115	55	8	8	NUM
aji-171	115	56	,	,	PUNCT
aji-171	115	57	no	no	INTJ
aji-171	115	58	.	.	NOUN
aji-171	115	59	1	1	NUM
aji-171	115	60	,	,	PUNCT
aji-171	115	61	pp	pp	ADJ
aji-171	115	62	.	.	PUNCT
aji-171	116	1	190	190	NUM
aji-171	116	2	-	-	SYM
aji-171	116	3	206	206	NUM
aji-171	116	4	,	,	PUNCT
aji-171	116	5	2025	2025	NUM
aji-171	116	6	;	;	PUNCT
aji-171	116	7	article	article	NOUN
aji-171	116	8	no.aji.140476	no.aji.140476	NOUN
aji-171	116	9	191	191	NUM
aji-171	116	10	abstract	abstract	ADJ
aji-171	116	11	the	the	DET
aji-171	116	12	field	field	NOUN
aji-171	116	13	of	of	ADP
aji-171	116	14	metabolomics	metabolomic	NOUN
aji-171	116	15	involves	involve	VERB
aji-171	116	16	the	the	DET
aji-171	116	17	high	high	ADJ
aji-171	116	18	-	-	PUNCT
aji-171	116	19	throughput	throughput	NOUN
aji-171	116	20	identification	identification	NOUN
aji-171	116	21	and	and	CCONJ
aji-171	116	22	measurement	measurement	NOUN
aji-171	116	23	of	of	ADP
aji-171	116	24	all	all	DET
aji-171	116	25	endogenous	endogenous	ADJ
aji-171	116	26	and	and	CCONJ
aji-171	116	27	exogenous	exogenous	ADJ
aji-171	116	28	low	low	ADJ
aji-171	116	29	-	-	PUNCT
aji-171	116	30	molecular	molecular	ADJ
aji-171	116	31	-	-	PUNCT
aji-171	116	32	weight	weight	NOUN
aji-171	116	33	(	(	PUNCT
aji-171	116	34	<	<	NOUN
aji-171	116	35	1kda	1kda	NUM
aji-171	116	36	)	)	PUNCT
aji-171	116	37	small	small	ADJ
aji-171	116	38	molecules	molecule	NOUN
aji-171	116	39	or	or	CCONJ
aji-171	116	40	metabolites	metabolite	NOUN
aji-171	116	41	in	in	ADP
aji-171	116	42	a	a	DET
aji-171	116	43	biological	biological	ADJ
aji-171	116	44	system	system	NOUN
aji-171	116	45	by	by	ADP
aji-171	116	46	analyzing	analyze	VERB
aji-171	116	47	the	the	DET
aji-171	116	48	metabolome	metabolome	NOUN
aji-171	116	49	in	in	ADP
aji-171	116	50	cells	cell	NOUN
aji-171	116	51	,	,	PUNCT
aji-171	116	52	biofluids	biofluid	NOUN
aji-171	116	53	,	,	PUNCT
aji-171	116	54	tissues	tissue	NOUN
aji-171	116	55	,	,	PUNCT
aji-171	116	56	or	or	CCONJ
aji-171	116	57	organisms	organism	NOUN
aji-171	116	58	.	.	PUNCT
aji-171	117	1	metabolome	metabolome	NOUN
aji-171	117	2	-	-	PUNCT
aji-171	117	3	wide	wide	ADJ
aji-171	117	4	association	association	NOUN
aji-171	117	5	studies	study	NOUN
aji-171	117	6	(	(	PUNCT
aji-171	117	7	mwas	mwas	NOUN
aji-171	117	8	)	)	PUNCT
aji-171	117	9	,	,	PUNCT
aji-171	117	10	metabolic	metabolic	NOUN
aji-171	117	11	phenotyping	phenotyping	NOUN
aji-171	117	12	,	,	PUNCT
aji-171	117	13	single	single	ADJ
aji-171	117	14	-	-	PUNCT
aji-171	117	15	cell	cell	NOUN
aji-171	117	16	epidemiologic	epidemiologic	ADJ
aji-171	117	17	population	population	NOUN
aji-171	117	18	studies	study	NOUN
aji-171	117	19	,	,	PUNCT
aji-171	117	20	precision	precision	NOUN
aji-171	117	21	metabolomics	metabolomic	NOUN
aji-171	117	22	,	,	PUNCT
aji-171	117	23	and	and	CCONJ
aji-171	117	24	in	in	ADP
aji-171	117	25	combination	combination	NOUN
aji-171	117	26	with	with	ADP
aji-171	117	27	other	other	ADJ
aji-171	117	28	omics	omic	NOUN
aji-171	117	29	fields	field	NOUN
aji-171	117	30	like	like	ADP
aji-171	117	31	integrative	integrative	ADJ
aji-171	117	32	omics	omic	NOUN
aji-171	117	33	,	,	PUNCT
aji-171	117	34	biotechnology	biotechnology	NOUN
aji-171	117	35	,	,	PUNCT
aji-171	117	36	and	and	CCONJ
aji-171	117	37	bioengineering	bioengineering	NOUN
aji-171	117	38	are	be	AUX
aji-171	117	39	some	some	PRON
aji-171	117	40	of	of	ADP
aji-171	117	41	the	the	DET
aji-171	117	42	applications	application	NOUN
aji-171	117	43	of	of	ADP
aji-171	117	44	metabolomics	metabolomic	NOUN
aji-171	117	45	in	in	ADP
aji-171	117	46	health	health	NOUN
aji-171	117	47	and	and	CCONJ
aji-171	117	48	disease	disease	NOUN
aji-171	117	49	scenarios	scenario	NOUN
aji-171	117	50	.	.	PUNCT
aji-171	118	1	metabolomics	metabolomic	NOUN
aji-171	118	2	and	and	CCONJ
aji-171	118	3	its	its	PRON
aji-171	118	4	potential	potential	NOUN
aji-171	118	5	to	to	PART
aji-171	118	6	enhance	enhance	VERB
aji-171	118	7	human	human	ADJ
aji-171	118	8	health	health	NOUN
aji-171	118	9	,	,	PUNCT
aji-171	118	10	along	along	ADP
aji-171	118	11	with	with	ADP
aji-171	118	12	its	its	PRON
aji-171	118	13	developments	development	NOUN
aji-171	118	14	and	and	CCONJ
aji-171	118	15	implications	implication	NOUN
aji-171	118	16	for	for	ADP
aji-171	118	17	pharmacometabolomics	pharmacometabolomic	NOUN
aji-171	118	18	,	,	PUNCT
aji-171	118	19	lifespan	lifespan	NOUN
aji-171	118	20	,	,	PUNCT
aji-171	118	21	cancer	cancer	NOUN
aji-171	118	22	,	,	PUNCT
aji-171	118	23	and	and	CCONJ
aji-171	118	24	the	the	DET
aji-171	118	25	exposome	exposome	NOUN
aji-171	118	26	,	,	PUNCT
aji-171	118	27	are	be	AUX
aji-171	118	28	the	the	DET
aji-171	118	29	main	main	ADJ
aji-171	118	30	focus	focus	NOUN
aji-171	118	31	of	of	ADP
aji-171	118	32	this	this	DET
aji-171	118	33	review	review	NOUN
aji-171	118	34	.	.	PUNCT
aji-171	119	1	metabolomic	metabolomic	ADJ
aji-171	119	2	profiles	profile	NOUN
aji-171	119	3	will	will	AUX
aji-171	119	4	facilitate	facilitate	VERB
aji-171	119	5	the	the	DET
aji-171	119	6	development	development	NOUN
aji-171	119	7	and	and	CCONJ
aji-171	119	8	improvement	improvement	NOUN
aji-171	119	9	of	of	ADP
aji-171	119	10	therapeutic	therapeutic	ADJ
aji-171	119	11	strategies	strategy	NOUN
aji-171	119	12	to	to	PART
aji-171	119	13	treat	treat	VERB
aji-171	119	14	human	human	ADJ
aji-171	119	15	diseases	disease	NOUN
aji-171	119	16	.	.	PUNCT
aji-171	120	1	future	future	ADJ
aji-171	120	2	years	year	NOUN
aji-171	120	3	will	will	AUX
aji-171	120	4	see	see	VERB
aji-171	120	5	a	a	DET
aji-171	120	6	rise	rise	NOUN
aji-171	120	7	in	in	ADP
aji-171	120	8	the	the	DET
aji-171	120	9	application	application	NOUN
aji-171	120	10	of	of	ADP
aji-171	120	11	metabolomics	metabolomic	NOUN
aji-171	120	12	to	to	ADP
aji-171	120	13	drug	drug	NOUN
aji-171	120	14	development	development	NOUN
aji-171	120	15	,	,	PUNCT
aji-171	120	16	aging	aging	NOUN
aji-171	120	17	,	,	PUNCT
aji-171	120	18	and	and	CCONJ
aji-171	120	19	disease	disease	NOUN
aji-171	120	20	monitoring	monitoring	NOUN
aji-171	120	21	and	and	CCONJ
aji-171	120	22	diagnosis	diagnosis	NOUN
aji-171	120	23	.	.	PUNCT
aji-171	121	1	its	its	PRON
aji-171	121	2	potential	potential	NOUN
aji-171	121	3	extends	extend	VERB
aji-171	121	4	to	to	ADP
aji-171	121	5	food	food	NOUN
aji-171	121	6	science	science	NOUN
aji-171	121	7	,	,	PUNCT
aji-171	121	8	and	and	CCONJ
aji-171	121	9	environmental	environmental	ADJ
aji-171	121	10	research	research	NOUN
aji-171	121	11	.	.	PUNCT
aji-171	122	1	through	through	ADP
aji-171	122	2	clinical	clinical	ADJ
aji-171	122	3	metabolomics	metabolomic	NOUN
aji-171	122	4	studies	study	NOUN
aji-171	122	5	,	,	PUNCT
aji-171	122	6	which	which	PRON
aji-171	122	7	may	may	AUX
aji-171	122	8	also	also	ADV
aji-171	122	9	uncover	uncover	VERB
aji-171	122	10	diagnostic	diagnostic	ADJ
aji-171	122	11	biomarkers	biomarker	NOUN
aji-171	122	12	that	that	PRON
aji-171	122	13	predict	predict	VERB
aji-171	122	14	disease	disease	NOUN
aji-171	122	15	risk	risk	NOUN
aji-171	122	16	,	,	PUNCT
aji-171	122	17	cardiometabolic	cardiometabolic	NOUN
aji-171	122	18	disorders	disorder	NOUN
aji-171	122	19	can	can	AUX
aji-171	122	20	be	be	AUX
aji-171	122	21	better	well	ADV
aji-171	122	22	understood	understand	VERB
aji-171	122	23	.	.	PUNCT
aji-171	123	1	metabolomics	metabolomic	NOUN
aji-171	123	2	is	be	AUX
aji-171	123	3	already	already	ADV
aji-171	123	4	being	be	AUX
aji-171	123	5	applied	apply	VERB
aji-171	123	6	in	in	ADP
aji-171	123	7	biomedical	biomedical	ADJ
aji-171	123	8	settings	setting	NOUN
aji-171	123	9	to	to	PART
aji-171	123	10	develop	develop	VERB
aji-171	123	11	drugs	drug	NOUN
aji-171	123	12	by	by	ADP
aji-171	123	13	using	use	VERB
aji-171	123	14	acylcarnitines	acylcarnitine	NOUN
aji-171	123	15	,	,	PUNCT
aji-171	123	16	phospholipids	phospholipid	NOUN
aji-171	123	17	,	,	PUNCT
aji-171	123	18	genomes	genome	NOUN
aji-171	123	19	,	,	PUNCT
aji-171	123	20	and	and	CCONJ
aji-171	123	21	branchchain	branchchain	NOUN
aji-171	123	22	amino	amino	NOUN
aji-171	123	23	acids	acid	NOUN
aji-171	123	24	that	that	PRON
aji-171	123	25	are	be	AUX
aji-171	123	26	specific	specific	ADJ
aji-171	123	27	to	to	ADP
aji-171	123	28	monitoring	monitor	VERB
aji-171	123	29	the	the	DET
aji-171	123	30	emergence	emergence	NOUN
aji-171	123	31	of	of	ADP
aji-171	123	32	metabolic	metabolic	NOUN
aji-171	123	33	diseases	disease	NOUN
aji-171	123	34	such	such	ADJ
aji-171	123	35	as	as	ADP
aji-171	123	36	obesity	obesity	NOUN
aji-171	123	37	and	and	CCONJ
aji-171	123	38	diabetes	diabetes	NOUN
aji-171	123	39	.	.	PUNCT
aji-171	124	1	indicators	indicator	NOUN
aji-171	124	2	derived	derive	VERB
aji-171	124	3	from	from	ADP
aji-171	124	4	metabolomics	metabolomic	NOUN
aji-171	124	5	should	should	AUX
aji-171	124	6	be	be	AUX
aji-171	124	7	evaluated	evaluate	VERB
aji-171	124	8	for	for	ADP
aji-171	124	9	therapeutic	therapeutic	ADJ
aji-171	124	10	efficacy	efficacy	NOUN
aji-171	124	11	and	and	CCONJ
aji-171	124	12	adaptability	adaptability	NOUN
aji-171	124	13	,	,	PUNCT
aji-171	124	14	and	and	CCONJ
aji-171	124	15	their	their	PRON
aji-171	124	16	optimal	optimal	ADJ
aji-171	124	17	application	application	NOUN
aji-171	124	18	in	in	ADP
aji-171	124	19	large	large	ADJ
aji-171	124	20	clinical	clinical	ADJ
aji-171	124	21	settings	setting	NOUN
aji-171	124	22	should	should	AUX
aji-171	124	23	be	be	AUX
aji-171	124	24	the	the	DET
aji-171	124	25	focus	focus	NOUN
aji-171	124	26	of	of	ADP
aji-171	124	27	future	future	ADJ
aji-171	124	28	research	research	NOUN
aji-171	124	29	.	.	PUNCT
aji-171	125	1	keywords	keyword	NOUN
aji-171	125	2	:	:	PUNCT
aji-171	125	3	metabolomics	metabolomic	NOUN
aji-171	125	4	;	;	PUNCT
aji-171	125	5	health	health	NOUN
aji-171	125	6	;	;	PUNCT
aji-171	125	7	disease	disease	NOUN
aji-171	125	8	;	;	PUNCT
aji-171	125	9	metabolites	metabolite	NOUN
aji-171	125	10	;	;	PUNCT
aji-171	125	11	biomarker	biomarker	NOUN
aji-171	125	12	.	.	PUNCT
aji-171	126	1	1	1	X
aji-171	126	2	.	.	X
aji-171	126	3	introduction	introduction	NOUN
aji-171	126	4	the	the	DET
aji-171	126	5	rapidly	rapidly	ADV
aji-171	126	6	developing	develop	VERB
aji-171	126	7	field	field	NOUN
aji-171	126	8	of	of	ADP
aji-171	126	9	metabolomics	metabolomic	NOUN
aji-171	126	10	aims	aim	NOUN
aji-171	126	11	to	to	PART
aji-171	126	12	accurately	accurately	ADV
aji-171	126	13	identify	identify	VERB
aji-171	126	14	and	and	CCONJ
aji-171	126	15	measure	measure	VERB
aji-171	126	16	all	all	DET
aji-171	126	17	endogenous	endogenous	ADJ
aji-171	126	18	and	and	CCONJ
aji-171	126	19	exogenous	exogenous	ADJ
aji-171	126	20	low	low	ADJ
aji-171	126	21	-	-	PUNCT
aji-171	126	22	molecularweight	molecularweight	NOUN
aji-171	126	23	(	(	PUNCT
aji-171	126	24	<	<	NOUN
aji-171	126	25	1kda	1kda	NUM
aji-171	126	26	)	)	PUNCT
aji-171	126	27	small	small	ADJ
aji-171	126	28	molecules	molecule	NOUN
aji-171	126	29	or	or	CCONJ
aji-171	126	30	metabolites	metabolite	NOUN
aji-171	126	31	in	in	ADP
aji-171	126	32	a	a	DET
aji-171	126	33	biological	biological	ADJ
aji-171	126	34	system	system	NOUN
aji-171	126	35	in	in	ADP
aji-171	126	36	a	a	DET
aji-171	126	37	high	high	ADJ
aji-171	126	38	-	-	PUNCT
aji-171	126	39	throughput	throughput	NOUN
aji-171	126	40	way	way	NOUN
aji-171	126	41	.	.	PUNCT
aji-171	127	1	the	the	DET
aji-171	127	2	proteome	proteome	NOUN
aji-171	127	3	,	,	PUNCT
aji-171	127	4	genome	genome	NOUN
aji-171	127	5	,	,	PUNCT
aji-171	127	6	lifestyle	lifestyle	NOUN
aji-171	127	7	,	,	PUNCT
aji-171	127	8	environment	environment	NOUN
aji-171	127	9	,	,	PUNCT
aji-171	127	10	drugs	drug	NOUN
aji-171	127	11	,	,	PUNCT
aji-171	127	12	and	and	CCONJ
aji-171	127	13	underlying	underlie	VERB
aji-171	127	14	disease	disease	NOUN
aji-171	127	15	all	all	PRON
aji-171	127	16	have	have	VERB
aji-171	127	17	an	an	DET
aji-171	127	18	upstream	upstream	ADJ
aji-171	127	19	influence	influence	NOUN
aji-171	127	20	on	on	ADP
aji-171	127	21	the	the	DET
aji-171	127	22	composition	composition	NOUN
aji-171	127	23	of	of	ADP
aji-171	127	24	these	these	DET
aji-171	127	25	endogenous	endogenous	ADJ
aji-171	127	26	compounds	compound	NOUN
aji-171	127	27	(	(	PUNCT
aji-171	127	28	zhou	zhou	PROPN
aji-171	127	29	and	and	CCONJ
aji-171	127	30	zhong	zhong	PROPN
aji-171	127	31	,	,	PUNCT
aji-171	127	32	2022	2022	NUM
aji-171	127	33	)	)	PUNCT
aji-171	127	34	.	.	PUNCT
aji-171	128	1	the	the	DET
aji-171	128	2	study	study	NOUN
aji-171	128	3	of	of	ADP
aji-171	128	4	metabolites	metabolite	NOUN
aji-171	128	5	,	,	PUNCT
aji-171	128	6	which	which	PRON
aji-171	128	7	are	be	AUX
aji-171	128	8	tiny	tiny	ADJ
aji-171	128	9	chemical	chemical	ADJ
aji-171	128	10	entities	entity	NOUN
aji-171	128	11	involved	involve	VERB
aji-171	128	12	in	in	ADP
aji-171	128	13	biological	biological	ADJ
aji-171	128	14	systems	system	NOUN
aji-171	128	15	'	'	PART
aji-171	128	16	cellular	cellular	ADJ
aji-171	128	17	processes	process	NOUN
aji-171	128	18	,	,	PUNCT
aji-171	128	19	is	be	AUX
aji-171	128	20	known	know	VERB
aji-171	128	21	as	as	ADP
aji-171	128	22	metabolomics	metabolomic	NOUN
aji-171	128	23	.	.	PUNCT
aji-171	129	1	it	it	PRON
aji-171	129	2	is	be	AUX
aji-171	129	3	used	use	VERB
aji-171	129	4	in	in	ADP
aji-171	129	5	molecular	molecular	ADJ
aji-171	129	6	and	and	CCONJ
aji-171	129	7	personalized	personalized	ADJ
aji-171	129	8	healthcare	healthcare	NOUN
aji-171	129	9	in	in	ADP
aji-171	129	10	clinical	clinical	ADJ
aji-171	129	11	chemistry	chemistry	NOUN
aji-171	129	12	,	,	PUNCT
aji-171	129	13	transplant	transplant	NOUN
aji-171	129	14	monitoring	monitoring	NOUN
aji-171	129	15	,	,	PUNCT
aji-171	129	16	newborn	newborn	ADJ
aji-171	129	17	screening	screening	NOUN
aji-171	129	18	,	,	PUNCT
aji-171	129	19	pharmacology	pharmacology	NOUN
aji-171	129	20	,	,	PUNCT
aji-171	129	21	and	and	CCONJ
aji-171	129	22	toxicology	toxicology	NOUN
aji-171	129	23	(	(	PUNCT
aji-171	129	24	zhou	zhou	PROPN
aji-171	129	25	and	and	CCONJ
aji-171	129	26	zhong	zhong	PROPN
aji-171	129	27	,	,	PUNCT
aji-171	129	28	2022	2022	NUM
aji-171	129	29	)	)	PUNCT
aji-171	129	30	.	.	PUNCT
aji-171	130	1	the	the	DET
aji-171	130	2	development	development	NOUN
aji-171	130	3	of	of	ADP
aji-171	130	4	analytical	analytical	ADJ
aji-171	130	5	techniques	technique	NOUN
aji-171	130	6	and	and	CCONJ
aji-171	130	7	bioinformatics	bioinformatics	NOUN
aji-171	130	8	has	have	AUX
aji-171	130	9	led	lead	VERB
aji-171	130	10	to	to	ADP
aji-171	130	11	the	the	DET
aji-171	130	12	emergence	emergence	NOUN
aji-171	130	13	of	of	ADP
aji-171	130	14	metabolomics	metabolomic	NOUN
aji-171	130	15	,	,	PUNCT
aji-171	130	16	a	a	DET
aji-171	130	17	state	state	NOUN
aji-171	130	18	-	-	PUNCT
aji-171	130	19	of	of	ADP
aji-171	130	20	-	-	PUNCT
aji-171	130	21	the	the	DET
aji-171	130	22	-	-	PUNCT
aji-171	130	23	art	art	NOUN
aji-171	130	24	omics	omic	NOUN
aji-171	130	25	technique	technique	NOUN
aji-171	130	26	.	.	PUNCT
aji-171	131	1	in	in	ADP
aji-171	131	2	order	order	NOUN
aji-171	131	3	to	to	PART
aji-171	131	4	identify	identify	VERB
aji-171	131	5	and	and	CCONJ
aji-171	131	6	describe	describe	VERB
aji-171	131	7	the	the	DET
aji-171	131	8	metabolome	metabolome	NOUN
aji-171	131	9	,	,	PUNCT
aji-171	131	10	the	the	DET
aji-171	131	11	metabolomics	metabolomic	NOUN
aji-171	131	12	approach	approach	NOUN
aji-171	131	13	typically	typically	ADV
aji-171	131	14	uses	use	VERB
aji-171	131	15	advanced	advanced	ADJ
aji-171	131	16	analytical	analytical	ADJ
aji-171	131	17	chemistry	chemistry	NOUN
aji-171	131	18	tools	tool	NOUN
aji-171	131	19	like	like	ADP
aji-171	131	20	nuclear	nuclear	ADJ
aji-171	131	21	magnetic	magnetic	ADJ
aji-171	131	22	resonance	resonance	NOUN
aji-171	131	23	(	(	PUNCT
aji-171	131	24	nmr	nmr	NOUN
aji-171	131	25	)	)	PUNCT
aji-171	131	26	and	and	CCONJ
aji-171	131	27	mass	mass	ADJ
aji-171	131	28	spectrometry	spectrometry	NOUN
aji-171	131	29	(	(	PUNCT
aji-171	131	30	ms	ms	NOUN
aji-171	131	31	)	)	PUNCT
aji-171	131	32	in	in	ADP
aji-171	131	33	conjunction	conjunction	NOUN
aji-171	131	34	with	with	ADP
aji-171	131	35	different	different	ADJ
aji-171	131	36	chromatographic	chromatographic	ADJ
aji-171	131	37	techniques	technique	NOUN
aji-171	131	38	,	,	PUNCT
aji-171	131	39	such	such	ADJ
aji-171	131	40	as	as	ADP
aji-171	131	41	gas	gas	NOUN
aji-171	131	42	chromatography	chromatography	NOUN
aji-171	131	43	(	(	PUNCT
aji-171	131	44	gc	gc	PROPN
aji-171	131	45	-	-	PUNCT
aji-171	131	46	ms	ms	NOUN
aji-171	131	47	)	)	PUNCT
aji-171	131	48	or	or	CCONJ
aji-171	131	49	liquid	liquid	ADJ
aji-171	131	50	chromatography	chromatography	NOUN
aji-171	131	51	(	(	PUNCT
aji-171	131	52	lc	lc	PROPN
aji-171	131	53	-	-	PUNCT
aji-171	131	54	ms	ms	NOUN
aji-171	131	55	)	)	PUNCT
aji-171	131	56	,	,	PUNCT
aji-171	131	57	with	with	ADP
aji-171	131	58	an	an	DET
aji-171	131	59	emphasis	emphasis	NOUN
aji-171	131	60	on	on	ADP
aji-171	131	61	molecules	molecule	NOUN
aji-171	131	62	smaller	small	ADJ
aji-171	131	63	than	than	ADP
aji-171	131	64	1500	1500	NUM
aji-171	131	65	da	da	NOUN
aji-171	131	66	found	find	VERB
aji-171	131	67	in	in	ADP
aji-171	131	68	cells	cell	NOUN
aji-171	131	69	,	,	PUNCT
aji-171	131	70	organs	organ	NOUN
aji-171	131	71	,	,	PUNCT
aji-171	131	72	tissues	tissue	NOUN
aji-171	131	73	,	,	PUNCT
aji-171	131	74	or	or	CCONJ
aji-171	131	75	biofluids	biofluid	NOUN
aji-171	131	76	(	(	PUNCT
aji-171	131	77	wishart	wishart	PROPN
aji-171	131	78	,	,	PUNCT
aji-171	131	79	2018	2018	NUM
aji-171	131	80	;	;	PUNCT
aji-171	131	81	sun	sun	PROPN
aji-171	131	82	et	et	PROPN
aji-171	131	83	al	al	PROPN
aji-171	131	84	.	.	PROPN
aji-171	131	85	,	,	PUNCT
aji-171	131	86	2019	2019	NUM
aji-171	131	87	)	)	PUNCT
aji-171	131	88	.	.	PUNCT
aji-171	132	1	the	the	DET
aji-171	132	2	new	new	ADJ
aji-171	132	3	field	field	NOUN
aji-171	132	4	of	of	ADP
aji-171	132	5	medical	medical	ADJ
aji-171	132	6	genomics	genomic	NOUN
aji-171	132	7	offers	offer	VERB
aji-171	132	8	cuttingedge	cuttingedge	ADJ
aji-171	132	9	technological	technological	ADJ
aji-171	132	10	instruments	instrument	NOUN
aji-171	132	11	for	for	ADP
aji-171	132	12	identifying	identify	VERB
aji-171	132	13	genetic	genetic	ADJ
aji-171	132	14	susceptibilities	susceptibility	NOUN
aji-171	132	15	to	to	ADP
aji-171	132	16	diseases	disease	NOUN
aji-171	132	17	.	.	PUNCT
aji-171	133	1	but	but	CCONJ
aji-171	133	2	metabolomics	metabolomic	NOUN
aji-171	133	3	allows	allow	VERB
aji-171	133	4	us	we	PRON
aji-171	133	5	to	to	PART
aji-171	133	6	go	go	VERB
aji-171	133	7	further	far	ADV
aji-171	133	8	by	by	ADP
aji-171	133	9	linking	link	VERB
aji-171	133	10	disorders	disorder	NOUN
aji-171	133	11	and	and	CCONJ
aji-171	133	12	defects	defect	NOUN
aji-171	133	13	in	in	ADP
aji-171	133	14	gene	gene	NOUN
aji-171	133	15	expression	expression	NOUN
aji-171	133	16	to	to	ADP
aji-171	133	17	the	the	DET
aji-171	133	18	pathological	pathological	ADJ
aji-171	133	19	phenotype	phenotype	NOUN
aji-171	133	20	.	.	PUNCT
aji-171	134	1	although	although	SCONJ
aji-171	134	2	the	the	DET
aji-171	134	3	concept	concept	NOUN
aji-171	134	4	of	of	ADP
aji-171	134	5	"	"	PUNCT
aji-171	134	6	clinical	clinical	ADJ
aji-171	134	7	metabolomics	metabolomic	NOUN
aji-171	134	8	"	"	PUNCT
aji-171	134	9	was	be	AUX
aji-171	134	10	first	first	ADV
aji-171	134	11	introduced	introduce	VERB
aji-171	134	12	in	in	ADP
aji-171	134	13	2008	2008	NUM
aji-171	134	14	,	,	PUNCT
aji-171	134	15	the	the	DET
aji-171	134	16	term	term	NOUN
aji-171	134	17	was	be	AUX
aji-171	134	18	first	first	ADV
aji-171	134	19	used	use	VERB
aji-171	134	20	in	in	ADP
aji-171	134	21	the	the	DET
aji-171	134	22	literature	literature	NOUN
aji-171	134	23	in	in	ADP
aji-171	134	24	2009	2009	NUM
aji-171	134	25	(	(	PUNCT
aji-171	134	26	le	le	AUX
aji-171	134	27	gouellec	gouellec	VERB
aji-171	134	28	et	et	PROPN
aji-171	134	29	al	al	PROPN
aji-171	134	30	.	.	PROPN
aji-171	134	31	,	,	PUNCT
aji-171	134	32	2023	2023	NUM
aji-171	134	33	)	)	PUNCT
aji-171	134	34	.	.	PUNCT
aji-171	135	1	the	the	DET
aji-171	135	2	goal	goal	NOUN
aji-171	135	3	of	of	ADP
aji-171	135	4	clinical	clinical	ADJ
aji-171	135	5	metabolomics	metabolomic	NOUN
aji-171	135	6	is	be	AUX
aji-171	135	7	to	to	PART
aji-171	135	8	identify	identify	VERB
aji-171	135	9	metabolic	metabolic	NOUN
aji-171	135	10	signatures	signature	NOUN
aji-171	135	11	in	in	ADP
aji-171	135	12	bodily	bodily	ADJ
aji-171	135	13	fluids	fluid	NOUN
aji-171	135	14	(	(	PUNCT
aji-171	135	15	plasma	plasma	NOUN
aji-171	135	16	,	,	PUNCT
aji-171	135	17	urine	urine	NOUN
aji-171	135	18	,	,	PUNCT
aji-171	135	19	saliva	saliva	NOUN
aji-171	135	20	,	,	PUNCT
aji-171	135	21	cerebrospinal	cerebrospinal	ADJ
aji-171	135	22	fluid	fluid	NOUN
aji-171	135	23	,	,	PUNCT
aji-171	135	24	etc	etc	X
aji-171	135	25	.	.	X
aji-171	135	26	)	)	PUNCT
aji-171	135	27	or	or	CCONJ
aji-171	135	28	tissues	tissue	NOUN
aji-171	135	29	that	that	PRON
aji-171	135	30	are	be	AUX
aji-171	135	31	impacted	impact	VERB
aji-171	135	32	by	by	ADP
aji-171	135	33	genetics	genetic	NOUN
aji-171	135	34	,	,	PUNCT
aji-171	135	35	epigenetics	epigenetic	NOUN
aji-171	135	36	,	,	PUNCT
aji-171	135	37	dietary	dietary	ADJ
aji-171	135	38	patterns	pattern	NOUN
aji-171	135	39	,	,	PUNCT
aji-171	135	40	environmental	environmental	ADJ
aji-171	135	41	factors	factor	NOUN
aji-171	135	42	,	,	PUNCT
aji-171	135	43	and	and	CCONJ
aji-171	135	44	behavior	behavior	NOUN
aji-171	135	45	in	in	ADP
aji-171	135	46	order	order	NOUN
aji-171	135	47	to	to	PART
aji-171	135	48	evaluate	evaluate	VERB
aji-171	135	49	and	and	CCONJ
aji-171	135	50	forecast	forecast	VERB
aji-171	135	51	a	a	DET
aji-171	135	52	subject	subject	NOUN
aji-171	135	53	's	's	PART
aji-171	135	54	health	health	NOUN
aji-171	135	55	and	and	CCONJ
aji-171	135	56	disease	disease	NOUN
aji-171	135	57	risk	risk	NOUN
aji-171	135	58	(	(	PUNCT
aji-171	135	59	ceglarek	ceglarek	NOUN
aji-171	135	60	et	et	PROPN
aji-171	135	61	al	al	PROPN
aji-171	135	62	.	.	PROPN
aji-171	135	63	,	,	PUNCT
aji-171	135	64	2009	2009	NUM
aji-171	135	65	;	;	PUNCT
aji-171	135	66	mallu	mallu	PROPN
aji-171	135	67	et	et	PROPN
aji-171	135	68	al	al	PROPN
aji-171	135	69	.	.	PROPN
aji-171	135	70	,	,	PUNCT
aji-171	135	71	2021	2021	NUM
aji-171	135	72	)	)	PUNCT
aji-171	135	73	.	.	PUNCT
aji-171	136	1	a	a	DET
aji-171	136	2	collection	collection	NOUN
aji-171	136	3	or	or	CCONJ
aji-171	136	4	combinations	combination	NOUN
aji-171	136	5	of	of	ADP
aji-171	136	6	impacted	impact	VERB
aji-171	136	7	metabolites	metabolite	NOUN
aji-171	136	8	make	make	VERB
aji-171	136	9	up	up	ADP
aji-171	136	10	metabolic	metabolic	NOUN
aji-171	136	11	signatures	signature	NOUN
aji-171	136	12	(	(	PUNCT
aji-171	136	13	wishart	wishart	NOUN
aji-171	136	14	,	,	PUNCT
aji-171	136	15	2018	2018	NUM
aji-171	136	16	)	)	PUNCT
aji-171	136	17	.	.	PUNCT
aji-171	137	1	metabolomics	metabolomic	NOUN
aji-171	137	2	'	'	PART
aji-171	137	3	use	use	NOUN
aji-171	137	4	in	in	ADP
aji-171	137	5	both	both	CCONJ
aji-171	137	6	health	health	NOUN
aji-171	137	7	and	and	CCONJ
aji-171	137	8	disease	disease	NOUN
aji-171	137	9	has	have	AUX
aji-171	137	10	grown	grow	VERB
aji-171	137	11	in	in	ADP
aji-171	137	12	importance	importance	NOUN
aji-171	137	13	.	.	PUNCT
aji-171	138	1	based	base	VERB
aji-171	138	2	on	on	ADP
aji-171	138	3	a	a	DET
aji-171	138	4	particular	particular	ADJ
aji-171	138	5	metabolic	metabolic	NOUN
aji-171	138	6	signature	signature	NOUN
aji-171	138	7	,	,	PUNCT
aji-171	138	8	metabolomics	metabolomic	NOUN
aji-171	138	9	makes	make	VERB
aji-171	138	10	it	it	PRON
aji-171	138	11	possible	possible	ADJ
aji-171	138	12	to	to	PART
aji-171	138	13	identify	identify	VERB
aji-171	138	14	biomarkers	biomarker	NOUN
aji-171	138	15	for	for	ADP
aji-171	138	16	disease	disease	NOUN
aji-171	138	17	diagnosis	diagnosis	NOUN
aji-171	138	18	,	,	PUNCT
aji-171	138	19	prognosis	prognosis	NOUN
aji-171	138	20	,	,	PUNCT
aji-171	138	21	and	and	CCONJ
aji-171	138	22	response	response	NOUN
aji-171	138	23	to	to	ADP
aji-171	138	24	treatment	treatment	NOUN
aji-171	138	25	(	(	PUNCT
aji-171	138	26	cheng	cheng	PROPN
aji-171	138	27	et	et	PROPN
aji-171	138	28	al	al	PROPN
aji-171	138	29	.	.	PROPN
aji-171	138	30	,	,	PUNCT
aji-171	138	31	2012	2012	NUM
aji-171	138	32	)	)	PUNCT
aji-171	138	33	.	.	PUNCT
aji-171	139	1	the	the	DET
aji-171	139	2	pathophysiology	pathophysiology	NOUN
aji-171	139	3	of	of	ADP
aji-171	139	4	complex	complex	ADJ
aji-171	139	5	diseases	disease	NOUN
aji-171	139	6	like	like	ADP
aji-171	139	7	cancer	cancer	NOUN
aji-171	139	8	,	,	PUNCT
aji-171	139	9	neurodegenerative	neurodegenerative	ADJ
aji-171	139	10	diseases	disease	NOUN
aji-171	139	11	,	,	PUNCT
aji-171	139	12	cardiovascular	cardiovascular	ADJ
aji-171	139	13	diseases	disease	NOUN
aji-171	139	14	,	,	PUNCT
aji-171	139	15	and	and	CCONJ
aji-171	139	16	metabolic	metabolic	NOUN
aji-171	139	17	syndrome	syndrome	NOUN
aji-171	139	18	can	can	AUX
aji-171	139	19	be	be	AUX
aji-171	139	20	largely	largely	ADV
aji-171	139	21	explained	explain	VERB
aji-171	139	22	by	by	ADP
aji-171	139	23	such	such	ADJ
aji-171	139	24	metabolic	metabolic	NOUN
aji-171	139	25	profiles	profile	NOUN
aji-171	139	26	(	(	PUNCT
aji-171	139	27	neergaard	neergaard	NOUN
aji-171	139	28	et	et	PROPN
aji-171	139	29	al	al	PROPN
aji-171	139	30	.	.	PROPN
aji-171	139	31	,	,	PUNCT
aji-171	139	32	2017	2017	NUM
aji-171	139	33	;	;	PUNCT
aji-171	139	34	mallu	mallu	PROPN
aji-171	139	35	et	et	PROPN
aji-171	139	36	al	al	PROPN
aji-171	139	37	.	.	PROPN
aji-171	139	38	,	,	PUNCT
aji-171	139	39	2021	2021	NUM
aji-171	139	40	;	;	PUNCT
aji-171	139	41	vo	vo	NOUN
aji-171	139	42	and	and	CCONJ
aji-171	139	43	trinh	trinh	PROPN
aji-171	139	44	,	,	PUNCT
aji-171	139	45	2024	2024	NUM
aji-171	139	46	)	)	PUNCT
aji-171	139	47	.	.	PUNCT
aji-171	140	1	furthermore	furthermore	ADV
aji-171	140	2	,	,	PUNCT
aji-171	140	3	metabolomics	metabolomic	NOUN
aji-171	140	4	is	be	AUX
aji-171	140	5	mamman	mamman	NOUN
aji-171	140	6	et	et	PROPN
aji-171	140	7	al	al	PROPN
aji-171	140	8	.	.	PROPN
aji-171	140	9	;	;	PUNCT
aji-171	140	10	asian	asian	PROPN
aji-171	140	11	j.	j.	PROPN
aji-171	140	12	immunol	immunol	PROPN
aji-171	140	13	.	.	PROPN
aji-171	140	14	,	,	PUNCT
aji-171	140	15	vol	vol	NOUN
aji-171	140	16	.	.	PROPN
aji-171	140	17	8	8	NUM
aji-171	140	18	,	,	PUNCT
aji-171	140	19	no	no	INTJ
aji-171	140	20	.	.	NOUN
aji-171	140	21	1	1	NUM
aji-171	140	22	,	,	PUNCT
aji-171	140	23	pp	pp	ADJ
aji-171	140	24	.	.	PUNCT
aji-171	141	1	190	190	NUM
aji-171	141	2	-	-	SYM
aji-171	141	3	206	206	NUM
aji-171	141	4	,	,	PUNCT
aji-171	141	5	2025	2025	NUM
aji-171	141	6	;	;	PUNCT
aji-171	141	7	article	article	NOUN
aji-171	141	8	no.aji.140476	no.aji.140476	PART
aji-171	141	9	192	192	NUM
aji-171	141	10	crucial	crucial	ADJ
aji-171	141	11	to	to	PART
aji-171	141	12	precision	precision	VERB
aji-171	141	13	medicine	medicine	NOUN
aji-171	141	14	because	because	SCONJ
aji-171	141	15	it	it	PRON
aji-171	141	16	allows	allow	VERB
aji-171	141	17	for	for	ADP
aji-171	141	18	the	the	DET
aji-171	141	19	identification	identification	NOUN
aji-171	141	20	of	of	ADP
aji-171	141	21	individual	individual	ADJ
aji-171	141	22	metabolic	metabolic	NOUN
aji-171	141	23	variations	variation	NOUN
aji-171	141	24	that	that	PRON
aji-171	141	25	can	can	AUX
aji-171	141	26	support	support	VERB
aji-171	141	27	tailored	tailor	VERB
aji-171	141	28	treatment	treatment	NOUN
aji-171	141	29	approaches	approach	NOUN
aji-171	141	30	(	(	PUNCT
aji-171	141	31	beger	beger	NOUN
aji-171	141	32	et	et	PROPN
aji-171	141	33	al	al	PROPN
aji-171	141	34	.	.	PROPN
aji-171	141	35	,	,	PUNCT
aji-171	141	36	2016	2016	NUM
aji-171	141	37	;	;	PUNCT
aji-171	141	38	nielsen	nielsen	PROPN
aji-171	141	39	,	,	PUNCT
aji-171	141	40	2017	2017	NUM
aji-171	141	41	)	)	PUNCT
aji-171	141	42	.	.	PUNCT
aji-171	142	1	according	accord	VERB
aji-171	142	2	to	to	ADP
aji-171	142	3	that	that	DET
aji-171	142	4	perspective	perspective	NOUN
aji-171	142	5	,	,	PUNCT
aji-171	142	6	metabolomics	metabolomic	NOUN
aji-171	142	7	is	be	AUX
aji-171	142	8	now	now	ADV
aji-171	142	9	a	a	DET
aji-171	142	10	potent	potent	ADJ
aji-171	142	11	addition	addition	NOUN
aji-171	142	12	to	to	ADP
aji-171	142	13	personalized	personalized	ADJ
aji-171	142	14	medicine	medicine	NOUN
aji-171	142	15	,	,	PUNCT
aji-171	142	16	bringing	bring	VERB
aji-171	142	17	fresh	fresh	ADJ
aji-171	142	18	insights	insight	NOUN
aji-171	142	19	into	into	ADP
aji-171	142	20	the	the	DET
aji-171	142	21	mechanisms	mechanism	NOUN
aji-171	142	22	underlying	underlie	VERB
aji-171	142	23	illnesses	illness	NOUN
aji-171	142	24	.	.	PUNCT
aji-171	143	1	biomarkers	biomarker	NOUN
aji-171	143	2	are	be	AUX
aji-171	143	3	important	important	ADJ
aji-171	143	4	in	in	ADP
aji-171	143	5	healthcare	healthcare	PROPN
aji-171	143	6	,	,	PUNCT
aji-171	143	7	particularly	particularly	ADV
aji-171	143	8	in	in	ADP
aji-171	143	9	diagnosis	diagnosis	NOUN
aji-171	143	10	,	,	PUNCT
aji-171	143	11	prognosis	prognosis	NOUN
aji-171	143	12	,	,	PUNCT
aji-171	143	13	and	and	CCONJ
aji-171	143	14	treatment	treatment	NOUN
aji-171	143	15	monitoring	monitoring	NOUN
aji-171	143	16	,	,	PUNCT
aji-171	143	17	since	since	SCONJ
aji-171	143	18	they	they	PRON
aji-171	143	19	are	be	AUX
aji-171	143	20	the	the	DET
aji-171	143	21	quantifiable	quantifiable	ADJ
aji-171	143	22	foundation	foundation	NOUN
aji-171	143	23	of	of	ADP
aji-171	143	24	biological	biological	ADJ
aji-171	143	25	states	state	NOUN
aji-171	143	26	and	and	CCONJ
aji-171	143	27	conditions	condition	NOUN
aji-171	143	28	(	(	PUNCT
aji-171	143	29	califf	califf	NOUN
aji-171	143	30	,	,	PUNCT
aji-171	143	31	2018	2018	NUM
aji-171	143	32	)	)	PUNCT
aji-171	143	33	.	.	PUNCT
aji-171	144	1	biomarkers	biomarker	NOUN
aji-171	144	2	are	be	AUX
aji-171	144	3	crucial	crucial	ADJ
aji-171	144	4	in	in	ADP
aji-171	144	5	diagnostics	diagnostic	NOUN
aji-171	144	6	because	because	SCONJ
aji-171	144	7	they	they	PRON
aji-171	144	8	enable	enable	VERB
aji-171	144	9	early	early	ADJ
aji-171	144	10	and	and	CCONJ
aji-171	144	11	precise	precise	ADJ
aji-171	144	12	disease	disease	NOUN
aji-171	144	13	diagnosis	diagnosis	NOUN
aji-171	144	14	,	,	PUNCT
aji-171	144	15	frequently	frequently	ADV
aji-171	144	16	before	before	SCONJ
aji-171	144	17	symptoms	symptom	NOUN
aji-171	144	18	appear	appear	VERB
aji-171	144	19	.	.	PUNCT
aji-171	145	1	this	this	PRON
aji-171	145	2	is	be	AUX
aji-171	145	3	especially	especially	ADV
aji-171	145	4	true	true	ADJ
aji-171	145	5	for	for	ADP
aji-171	145	6	diseases	disease	NOUN
aji-171	145	7	like	like	ADP
aji-171	145	8	cancer	cancer	NOUN
aji-171	145	9	,	,	PUNCT
aji-171	145	10	where	where	SCONJ
aji-171	145	11	early	early	ADJ
aji-171	145	12	intervention	intervention	NOUN
aji-171	145	13	greatly	greatly	ADV
aji-171	145	14	enhances	enhance	VERB
aji-171	145	15	results	result	NOUN
aji-171	145	16	.	.	PUNCT
aji-171	146	1	particular	particular	ADJ
aji-171	146	2	metabolite	metabolite	NOUN
aji-171	146	3	profiles	profile	NOUN
aji-171	146	4	,	,	PUNCT
aji-171	146	5	for	for	ADP
aji-171	146	6	instance	instance	NOUN
aji-171	146	7	,	,	PUNCT
aji-171	146	8	can	can	AUX
aji-171	146	9	help	help	AUX
aji-171	146	10	distinguish	distinguish	VERB
aji-171	146	11	between	between	ADP
aji-171	146	12	disease	disease	NOUN
aji-171	146	13	stages	stage	NOUN
aji-171	146	14	or	or	CCONJ
aji-171	146	15	subtypes	subtype	NOUN
aji-171	146	16	in	in	ADP
aji-171	146	17	order	order	NOUN
aji-171	146	18	to	to	PART
aji-171	146	19	improve	improve	VERB
aji-171	146	20	diagnostic	diagnostic	ADJ
aji-171	146	21	accuracy	accuracy	NOUN
aji-171	146	22	and	and	CCONJ
aji-171	146	23	support	support	NOUN
aji-171	146	24	patient	patient	ADJ
aji-171	146	25	stratification	stratification	NOUN
aji-171	146	26	(	(	PUNCT
aji-171	146	27	prat	prat	NOUN
aji-171	146	28	et	et	PROPN
aji-171	146	29	al	al	PROPN
aji-171	146	30	.	.	PROPN
aji-171	146	31	,	,	PUNCT
aji-171	146	32	2021	2021	NUM
aji-171	146	33	;	;	PUNCT
aji-171	146	34	deng	deng	PROPN
aji-171	146	35	et	et	PROPN
aji-171	146	36	al	al	PROPN
aji-171	146	37	.	.	PROPN
aji-171	146	38	,	,	PUNCT
aji-171	146	39	2022	2022	NUM
aji-171	146	40	)	)	PUNCT
aji-171	146	41	.	.	PUNCT
aji-171	147	1	identifying	identify	VERB
aji-171	147	2	markers	marker	NOUN
aji-171	147	3	of	of	ADP
aji-171	147	4	disease	disease	NOUN
aji-171	147	5	severity	severity	NOUN
aji-171	147	6	or	or	CCONJ
aji-171	147	7	recurrence	recurrence	NOUN
aji-171	147	8	can	can	AUX
aji-171	147	9	help	help	VERB
aji-171	147	10	healthcare	healthcare	NOUN
aji-171	147	11	providers	provider	NOUN
aji-171	147	12	predict	predict	VERB
aji-171	147	13	disease	disease	NOUN
aji-171	147	14	trajectory	trajectory	NOUN
aji-171	147	15	and	and	CCONJ
aji-171	147	16	appropriately	appropriately	ADV
aji-171	147	17	plan	plan	VERB
aji-171	147	18	interventions	intervention	NOUN
aji-171	147	19	,	,	PUNCT
aji-171	147	20	especially	especially	ADV
aji-171	147	21	for	for	ADP
aji-171	147	22	chronic	chronic	ADJ
aji-171	147	23	and	and	CCONJ
aji-171	147	24	complex	complex	ADJ
aji-171	147	25	diseases	disease	NOUN
aji-171	147	26	where	where	SCONJ
aji-171	147	27	metabolic	metabolic	NOUN
aji-171	147	28	biomarkers	biomarker	NOUN
aji-171	147	29	may	may	AUX
aji-171	147	30	indicate	indicate	VERB
aji-171	147	31	the	the	DET
aji-171	147	32	risk	risk	NOUN
aji-171	147	33	for	for	ADP
aji-171	147	34	complications	complication	NOUN
aji-171	147	35	or	or	CCONJ
aji-171	147	36	rapid	rapid	ADJ
aji-171	147	37	development	development	NOUN
aji-171	147	38	of	of	ADP
aji-171	147	39	the	the	DET
aji-171	147	40	disease	disease	NOUN
aji-171	147	41	process	process	NOUN
aji-171	147	42	.	.	PUNCT
aji-171	148	1	biomarkers	biomarker	NOUN
aji-171	148	2	help	help	VERB
aji-171	148	3	monitor	monitor	VERB
aji-171	148	4	treatments	treatment	NOUN
aji-171	148	5	by	by	ADP
aji-171	148	6	providing	provide	VERB
aji-171	148	7	real	real	ADJ
aji-171	148	8	-	-	PUNCT
aji-171	148	9	time	time	NOUN
aji-171	148	10	responses	response	NOUN
aji-171	148	11	in	in	ADP
aji-171	148	12	patients	patient	NOUN
aji-171	148	13	,	,	PUNCT
aji-171	148	14	allowing	allow	VERB
aji-171	148	15	for	for	ADP
aji-171	148	16	the	the	DET
aji-171	148	17	examination	examination	NOUN
aji-171	148	18	of	of	ADP
aji-171	148	19	efficacy	efficacy	NOUN
aji-171	148	20	and	and	CCONJ
aji-171	148	21	possible	possible	ADJ
aji-171	148	22	treatmentrelated	treatmentrelated	ADJ
aji-171	148	23	side	side	NOUN
aji-171	148	24	effects	effect	NOUN
aji-171	148	25	,	,	PUNCT
aji-171	148	26	allowing	allow	VERB
aji-171	148	27	for	for	ADP
aji-171	148	28	modifications	modification	NOUN
aji-171	148	29	of	of	ADP
aji-171	148	30	therapeutic	therapeutic	ADJ
aji-171	148	31	regimens	regimen	NOUN
aji-171	148	32	for	for	ADP
aji-171	148	33	maximum	maximum	ADJ
aji-171	148	34	efficacy	efficacy	NOUN
aji-171	148	35	with	with	ADP
aji-171	148	36	minimum	minimum	ADJ
aji-171	148	37	side	side	NOUN
aji-171	148	38	effects	effect	NOUN
aji-171	148	39	(	(	PUNCT
aji-171	148	40	vo	vo	X
aji-171	148	41	and	and	CCONJ
aji-171	148	42	trinh	trinh	PROPN
aji-171	148	43	,	,	PUNCT
aji-171	148	44	2024	2024	NUM
aji-171	148	45	)	)	PUNCT
aji-171	148	46	.	.	PUNCT
aji-171	149	1	according	accord	VERB
aji-171	149	2	to	to	ADP
aji-171	149	3	vargas	vargas	PROPN
aji-171	149	4	and	and	CCONJ
aji-171	149	5	harris	harris	PROPN
aji-171	149	6	(	(	PUNCT
aji-171	149	7	2016	2016	NUM
aji-171	149	8	)	)	PUNCT
aji-171	149	9	,	,	PUNCT
aji-171	149	10	biomarkers	biomarker	NOUN
aji-171	149	11	play	play	VERB
aji-171	149	12	a	a	DET
aji-171	149	13	significant	significant	ADJ
aji-171	149	14	role	role	NOUN
aji-171	149	15	in	in	ADP
aji-171	149	16	advancing	advance	VERB
aji-171	149	17	precision	precision	NOUN
aji-171	149	18	medicine	medicine	NOUN
aji-171	149	19	by	by	ADP
aji-171	149	20	facilitating	facilitate	VERB
aji-171	149	21	more	more	ADV
aji-171	149	22	individualized	individualized	ADJ
aji-171	149	23	,	,	PUNCT
aji-171	149	24	proactive	proactive	ADJ
aji-171	149	25	,	,	PUNCT
aji-171	149	26	and	and	CCONJ
aji-171	149	27	efficient	efficient	ADJ
aji-171	149	28	approaches	approach	NOUN
aji-171	149	29	to	to	ADP
aji-171	149	30	healthcare	healthcare	NOUN
aji-171	149	31	delivery	delivery	NOUN
aji-171	149	32	.	.	PUNCT
aji-171	150	1	new	new	ADJ
aji-171	150	2	technical	technical	ADJ
aji-171	150	3	tools	tool	NOUN
aji-171	150	4	for	for	ADP
aji-171	150	5	identifying	identify	VERB
aji-171	150	6	genetic	genetic	ADJ
aji-171	150	7	susceptibilities	susceptibility	NOUN
aji-171	150	8	to	to	ADP
aji-171	150	9	diseases	disease	NOUN
aji-171	150	10	have	have	AUX
aji-171	150	11	emerged	emerge	VERB
aji-171	150	12	with	with	ADP
aji-171	150	13	the	the	DET
aji-171	150	14	recent	recent	ADJ
aji-171	150	15	rise	rise	NOUN
aji-171	150	16	of	of	ADP
aji-171	150	17	medical	medical	ADJ
aji-171	150	18	genomics	genomic	NOUN
aji-171	150	19	.	.	PUNCT
aji-171	151	1	however	however	ADV
aji-171	151	2	,	,	PUNCT
aji-171	151	3	by	by	ADP
aji-171	151	4	linking	link	VERB
aji-171	151	5	the	the	DET
aji-171	151	6	pathological	pathological	ADJ
aji-171	151	7	phenotype	phenotype	NOUN
aji-171	151	8	to	to	ADP
aji-171	151	9	disorders	disorder	NOUN
aji-171	151	10	and	and	CCONJ
aji-171	151	11	defects	defect	NOUN
aji-171	151	12	in	in	ADP
aji-171	151	13	gene	gene	NOUN
aji-171	151	14	expression	expression	NOUN
aji-171	151	15	,	,	PUNCT
aji-171	151	16	metabolomics	metabolomic	NOUN
aji-171	151	17	allows	allow	VERB
aji-171	151	18	us	we	PRON
aji-171	151	19	to	to	PART
aji-171	151	20	go	go	VERB
aji-171	151	21	further	far	ADV
aji-171	151	22	.	.	PUNCT
aji-171	152	1	while	while	SCONJ
aji-171	152	2	the	the	DET
aji-171	152	3	concept	concept	NOUN
aji-171	152	4	was	be	AUX
aji-171	152	5	first	first	ADV
aji-171	152	6	introduced	introduce	VERB
aji-171	152	7	in	in	ADP
aji-171	152	8	2008	2008	NUM
aji-171	152	9	,	,	PUNCT
aji-171	152	10	the	the	DET
aji-171	152	11	term	term	NOUN
aji-171	152	12	"	"	PUNCT
aji-171	152	13	clinical	clinical	ADJ
aji-171	152	14	metabolomics	metabolomic	NOUN
aji-171	152	15	"	"	PUNCT
aji-171	152	16	was	be	AUX
aji-171	152	17	first	first	ADV
aji-171	152	18	used	use	VERB
aji-171	152	19	in	in	ADP
aji-171	152	20	the	the	DET
aji-171	152	21	literature	literature	NOUN
aji-171	152	22	in	in	ADP
aji-171	152	23	2009	2009	NUM
aji-171	152	24	(	(	PUNCT
aji-171	152	25	damiani	damiani	PROPN
aji-171	152	26	et	et	PROPN
aji-171	152	27	al	al	PROPN
aji-171	152	28	.	.	PROPN
aji-171	152	29	,	,	PUNCT
aji-171	152	30	2020	2020	NUM
aji-171	152	31	)	)	PUNCT
aji-171	152	32	.	.	PUNCT
aji-171	153	1	in	in	ADP
aji-171	153	2	clinical	clinical	ADJ
aji-171	153	3	metabolomics	metabolomic	NOUN
aji-171	153	4	,	,	PUNCT
aji-171	153	5	metabolic	metabolic	NOUN
aji-171	153	6	signatures	signature	NOUN
aji-171	153	7	in	in	ADP
aji-171	153	8	bodily	bodily	ADJ
aji-171	153	9	fluids	fluid	NOUN
aji-171	153	10	(	(	PUNCT
aji-171	153	11	plasma	plasma	NOUN
aji-171	153	12	,	,	PUNCT
aji-171	153	13	urine	urine	NOUN
aji-171	153	14	,	,	PUNCT
aji-171	153	15	saliva	saliva	NOUN
aji-171	153	16	,	,	PUNCT
aji-171	153	17	cerebrospinal	cerebrospinal	ADJ
aji-171	153	18	fluid	fluid	NOUN
aji-171	153	19	,	,	PUNCT
aji-171	153	20	etc	etc	X
aji-171	153	21	.	.	X
aji-171	153	22	)	)	PUNCT
aji-171	153	23	or	or	CCONJ
aji-171	153	24	tissues	tissue	NOUN
aji-171	153	25	which	which	PRON
aji-171	153	26	are	be	AUX
aji-171	153	27	influenced	influence	VERB
aji-171	153	28	by	by	ADP
aji-171	153	29	genetics	genetic	NOUN
aji-171	153	30	,	,	PUNCT
aji-171	153	31	epigenetics	epigenetic	NOUN
aji-171	153	32	,	,	PUNCT
aji-171	153	33	dietary	dietary	ADJ
aji-171	153	34	patterns	pattern	NOUN
aji-171	153	35	,	,	PUNCT
aji-171	153	36	environmental	environmental	ADJ
aji-171	153	37	factors	factor	NOUN
aji-171	153	38	,	,	PUNCT
aji-171	153	39	and	and	CCONJ
aji-171	153	40	behavior	behavior	NOUN
aji-171	153	41	are	be	AUX
aji-171	153	42	identified	identify	VERB
aji-171	153	43	in	in	ADP
aji-171	153	44	order	order	NOUN
aji-171	153	45	to	to	PART
aji-171	153	46	evaluate	evaluate	VERB
aji-171	153	47	and	and	CCONJ
aji-171	153	48	forecast	forecast	VERB
aji-171	153	49	a	a	DET
aji-171	153	50	subject	subject	NOUN
aji-171	153	51	's	's	PART
aji-171	153	52	health	health	NOUN
aji-171	153	53	and	and	CCONJ
aji-171	153	54	disease	disease	NOUN
aji-171	153	55	risk	risk	NOUN
aji-171	153	56	(	(	PUNCT
aji-171	153	57	cheng	cheng	PROPN
aji-171	153	58	et	et	PROPN
aji-171	153	59	al	al	PROPN
aji-171	153	60	.	.	PROPN
aji-171	153	61	,	,	PUNCT
aji-171	153	62	2012	2012	NUM
aji-171	153	63	)	)	PUNCT
aji-171	153	64	.	.	PUNCT
aji-171	154	1	a	a	DET
aji-171	154	2	group	group	NOUN
aji-171	154	3	or	or	CCONJ
aji-171	154	4	combination	combination	NOUN
aji-171	154	5	of	of	ADP
aji-171	154	6	metabolites	metabolite	NOUN
aji-171	154	7	that	that	PRON
aji-171	154	8	are	be	AUX
aji-171	154	9	impacted	impact	VERB
aji-171	154	10	make	make	VERB
aji-171	154	11	up	up	ADP
aji-171	154	12	metabolic	metabolic	NOUN
aji-171	154	13	signatures	signature	NOUN
aji-171	154	14	.	.	PUNCT
aji-171	155	1	in	in	ADP
aji-171	155	2	addition	addition	NOUN
aji-171	155	3	to	to	ADP
aji-171	155	4	being	be	AUX
aji-171	155	5	studied	study	VERB
aji-171	155	6	peripherally	peripherally	ADV
aji-171	155	7	,	,	PUNCT
aji-171	155	8	as	as	ADP
aji-171	155	9	in	in	ADP
aji-171	155	10	biofluids	biofluid	NOUN
aji-171	155	11	like	like	ADP
aji-171	155	12	blood	blood	NOUN
aji-171	155	13	plasma	plasma	NOUN
aji-171	155	14	,	,	PUNCT
aji-171	155	15	which	which	PRON
aji-171	155	16	contains	contain	VERB
aji-171	155	17	a	a	DET
aji-171	155	18	variety	variety	NOUN
aji-171	155	19	of	of	ADP
aji-171	155	20	metabolites	metabolite	NOUN
aji-171	155	21	that	that	PRON
aji-171	155	22	reflect	reflect	VERB
aji-171	155	23	organ	organ	NOUN
aji-171	155	24	metabolic	metabolic	NOUN
aji-171	155	25	activity	activity	NOUN
aji-171	155	26	and	and	CCONJ
aji-171	155	27	offer	offer	VERB
aji-171	155	28	important	important	ADJ
aji-171	155	29	pathophysiological	pathophysiological	ADJ
aji-171	155	30	information	information	NOUN
aji-171	155	31	,	,	PUNCT
aji-171	155	32	the	the	DET
aji-171	155	33	metabolome	metabolome	NOUN
aji-171	155	34	can	can	AUX
aji-171	155	35	also	also	ADV
aji-171	155	36	be	be	AUX
aji-171	155	37	studied	study	VERB
aji-171	155	38	intracellularly	intracellularly	ADV
aji-171	155	39	,	,	PUNCT
aji-171	155	40	exposing	expose	VERB
aji-171	155	41	functional	functional	ADJ
aji-171	155	42	abnormalities	abnormality	NOUN
aji-171	155	43	at	at	ADP
aji-171	155	44	the	the	DET
aji-171	155	45	cellular	cellular	ADJ
aji-171	155	46	level	level	NOUN
aji-171	155	47	(	(	PUNCT
aji-171	155	48	vo	vo	NOUN
aji-171	155	49	and	and	CCONJ
aji-171	155	50	trinh	trinh	PROPN
aji-171	155	51	,	,	PUNCT
aji-171	155	52	2024	2024	NUM
aji-171	155	53	)	)	PUNCT
aji-171	155	54	.	.	PUNCT
aji-171	156	1	human	human	ADJ
aji-171	156	2	plasma	plasma	NOUN
aji-171	156	3	contains	contain	VERB
aji-171	156	4	both	both	CCONJ
aji-171	156	5	endogenous	endogenous	ADJ
aji-171	156	6	and	and	CCONJ
aji-171	156	7	environmental	environmental	ADJ
aji-171	156	8	metabolites	metabolite	NOUN
aji-171	156	9	.	.	PUNCT
aji-171	157	1	a	a	DET
aji-171	157	2	number	number	NOUN
aji-171	157	3	of	of	ADP
aji-171	157	4	factors	factor	NOUN
aji-171	157	5	,	,	PUNCT
aji-171	157	6	including	include	VERB
aji-171	157	7	dietary	dietary	ADJ
aji-171	157	8	patterns	pattern	NOUN
aji-171	157	9	,	,	PUNCT
aji-171	157	10	gut	gut	NOUN
aji-171	157	11	microbiota	microbiota	NOUN
aji-171	157	12	,	,	PUNCT
aji-171	157	13	and	and	CCONJ
aji-171	157	14	lifestyle	lifestyle	NOUN
aji-171	157	15	choices	choice	NOUN
aji-171	157	16	(	(	PUNCT
aji-171	157	17	such	such	ADJ
aji-171	157	18	as	as	ADP
aji-171	157	19	smoking	smoking	NOUN
aji-171	157	20	or	or	CCONJ
aji-171	157	21	physical	physical	ADJ
aji-171	157	22	activity	activity	NOUN
aji-171	157	23	)	)	PUNCT
aji-171	157	24	,	,	PUNCT
aji-171	157	25	greatly	greatly	ADV
aji-171	157	26	impact	impact	VERB
aji-171	157	27	the	the	DET
aji-171	157	28	metabolome	metabolome	NOUN
aji-171	157	29	's	's	PART
aji-171	157	30	variability	variability	NOUN
aji-171	157	31	,	,	PUNCT
aji-171	157	32	which	which	PRON
aji-171	157	33	is	be	AUX
aji-171	157	34	partially	partially	ADV
aji-171	157	35	inherited	inherit	VERB
aji-171	157	36	.	.	PUNCT
aji-171	158	1	individual	individual	ADJ
aji-171	158	2	metabolic	metabolic	NOUN
aji-171	158	3	variability	variability	NOUN
aji-171	158	4	is	be	AUX
aji-171	158	5	mostly	mostly	ADV
aji-171	158	6	influenced	influence	VERB
aji-171	158	7	by	by	ADP
aji-171	158	8	diet	diet	NOUN
aji-171	158	9	and	and	CCONJ
aji-171	158	10	microbiota	microbiota	NOUN
aji-171	158	11	,	,	PUNCT
aji-171	158	12	which	which	PRON
aji-171	158	13	makes	make	VERB
aji-171	158	14	each	each	DET
aji-171	158	15	person	person	NOUN
aji-171	158	16	's	's	PART
aji-171	158	17	metabotype	metabotype	NOUN
aji-171	158	18	distinct	distinct	ADJ
aji-171	158	19	(	(	PUNCT
aji-171	158	20	vo	vo	X
aji-171	158	21	and	and	CCONJ
aji-171	158	22	trinh	trinh	PROPN
aji-171	158	23	,	,	PUNCT
aji-171	158	24	2024	2024	NUM
aji-171	158	25	)	)	PUNCT
aji-171	158	26	.	.	PUNCT
aji-171	159	1	nonetheless	nonetheless	ADV
aji-171	159	2	,	,	PUNCT
aji-171	159	3	a	a	DET
aji-171	159	4	person	person	NOUN
aji-171	159	5	's	's	PART
aji-171	159	6	metabotype	metabotype	NOUN
aji-171	159	7	stays	stay	VERB
aji-171	159	8	largely	largely	ADV
aji-171	159	9	constant	constant	ADJ
aji-171	159	10	over	over	ADP
aji-171	159	11	time	time	NOUN
aji-171	159	12	if	if	SCONJ
aji-171	159	13	there	there	PRON
aji-171	159	14	are	be	VERB
aji-171	159	15	no	no	DET
aji-171	159	16	notable	notable	ADJ
aji-171	159	17	changes	change	NOUN
aji-171	159	18	in	in	ADP
aji-171	159	19	their	their	PRON
aji-171	159	20	health	health	NOUN
aji-171	159	21	.	.	PUNCT
aji-171	160	1	the	the	DET
aji-171	160	2	analysis	analysis	NOUN
aji-171	160	3	of	of	ADP
aji-171	160	4	metabolites	metabolite	NOUN
aji-171	160	5	is	be	AUX
aji-171	160	6	predicated	predicate	VERB
aji-171	160	7	on	on	ADP
aji-171	160	8	two	two	NUM
aji-171	160	9	broad	broad	ADJ
aji-171	160	10	methods	method	NOUN
aji-171	160	11	:	:	PUNCT
aji-171	160	12	1	1	X
aji-171	160	13	.	.	NUM
aji-171	160	14	targeted	target	VERB
aji-171	160	15	metabolomics	metabolomic	NOUN
aji-171	160	16	is	be	AUX
aji-171	160	17	the	the	DET
aji-171	160	18	study	study	NOUN
aji-171	160	19	of	of	ADP
aji-171	160	20	identifying	identify	VERB
aji-171	160	21	a	a	DET
aji-171	160	22	particular	particular	ADJ
aji-171	160	23	group	group	NOUN
aji-171	160	24	of	of	ADP
aji-171	160	25	metabolites	metabolite	NOUN
aji-171	160	26	.	.	PUNCT
aji-171	161	1	2	2	X
aji-171	161	2	.	.	NUM
aji-171	161	3	untargeted	untargete	VERB
aji-171	161	4	metabolomics	metabolomic	NOUN
aji-171	161	5	compares	compare	NOUN
aji-171	161	6	and	and	CCONJ
aji-171	161	7	identifies	identify	VERB
aji-171	161	8	as	as	ADP
aji-171	161	9	many	many	ADJ
aji-171	161	10	metabolites	metabolite	NOUN
aji-171	161	11	as	as	ADP
aji-171	161	12	possible	possible	ADJ
aji-171	161	13	between	between	ADP
aji-171	161	14	samples	sample	NOUN
aji-171	161	15	,	,	PUNCT
aji-171	161	16	including	include	VERB
aji-171	161	17	unknown	unknown	ADJ
aji-171	161	18	ones	one	NOUN
aji-171	161	19	,	,	PUNCT
aji-171	161	20	using	use	VERB
aji-171	161	21	an	an	DET
aji-171	161	22	objective	objective	ADJ
aji-171	161	23	method	method	NOUN
aji-171	161	24	.	.	PUNCT
aji-171	162	1	the	the	DET
aji-171	162	2	latter	latter	ADJ
aji-171	162	3	strategy	strategy	NOUN
aji-171	162	4	allows	allow	VERB
aji-171	162	5	for	for	ADP
aji-171	162	6	the	the	DET
aji-171	162	7	routine	routine	ADJ
aji-171	162	8	detection	detection	NOUN
aji-171	162	9	of	of	ADP
aji-171	162	10	numerous	numerous	ADJ
aji-171	162	11	metabolite	metabolite	NOUN
aji-171	162	12	features	feature	NOUN
aji-171	162	13	peaks	peak	NOUN
aji-171	162	14	that	that	PRON
aji-171	162	15	correspond	correspond	VERB
aji-171	162	16	to	to	ADP
aji-171	162	17	individual	individual	ADJ
aji-171	162	18	ions	ion	NOUN
aji-171	162	19	with	with	ADP
aji-171	162	20	unique	unique	ADJ
aji-171	162	21	mass	mass	NOUN
aji-171	162	22	-	-	PUNCT
aji-171	162	23	to	to	ADP
aji-171	162	24	-	-	PUNCT
aji-171	162	25	charge	charge	NOUN
aji-171	162	26	(	(	PUNCT
aji-171	162	27	m	m	NOUN
aji-171	162	28	/	/	SYM
aji-171	162	29	z	z	NOUN
aji-171	162	30	)	)	PUNCT
aji-171	162	31	ratios	ratio	NOUN
aji-171	162	32	and	and	CCONJ
aji-171	162	33	retention	retention	NOUN
aji-171	162	34	times	time	NOUN
aji-171	162	35	(	(	PUNCT
aji-171	162	36	rt	rt	PROPN
aji-171	162	37	)	)	PUNCT
aji-171	162	38	using	use	VERB
aji-171	162	39	lc	lc	PROPN
aji-171	162	40	/	/	SYM
aji-171	162	41	ms	ms	NOUN
aji-171	162	42	-	-	PUNCT
aji-171	162	43	based	base	VERB
aji-171	162	44	techniques	technique	NOUN
aji-171	162	45	(	(	PUNCT
aji-171	162	46	vo	vo	X
aji-171	162	47	and	and	CCONJ
aji-171	162	48	trinh	trinh	PROPN
aji-171	162	49	,	,	PUNCT
aji-171	162	50	2024).the	2024).the	DET
aji-171	162	51	particular	particular	ADJ
aji-171	162	52	intended	intend	VERB
aji-171	162	53	application	application	NOUN
aji-171	162	54	will	will	AUX
aji-171	162	55	determine	determine	VERB
aji-171	162	56	which	which	PRON
aji-171	162	57	of	of	ADP
aji-171	162	58	these	these	DET
aji-171	162	59	methods	method	NOUN
aji-171	162	60	is	be	AUX
aji-171	162	61	best	good	ADJ
aji-171	162	62	.	.	PUNCT
aji-171	163	1	the	the	DET
aji-171	163	2	general	general	ADJ
aji-171	163	3	trends	trend	NOUN
aji-171	163	4	of	of	ADP
aji-171	163	5	recent	recent	ADJ
aji-171	163	6	discoveries	discovery	NOUN
aji-171	163	7	and	and	CCONJ
aji-171	163	8	applications	application	NOUN
aji-171	163	9	of	of	ADP
aji-171	163	10	metabolomics	metabolomic	NOUN
aji-171	163	11	-	-	PUNCT
aji-171	163	12	based	base	VERB
aji-171	163	13	biomarkers	biomarker	NOUN
aji-171	163	14	,	,	PUNCT
aji-171	163	15	as	as	ADV
aji-171	163	16	well	well	ADV
aji-171	163	17	as	as	ADP
aji-171	163	18	their	their	PRON
aji-171	163	19	revolutionary	revolutionary	ADJ
aji-171	163	20	effects	effect	NOUN
aji-171	163	21	on	on	ADP
aji-171	163	22	personalized	personalized	ADJ
aji-171	163	23	medicine	medicine	NOUN
aji-171	163	24	and	and	CCONJ
aji-171	163	25	precision	precision	NOUN
aji-171	163	26	health	health	NOUN
aji-171	163	27	,	,	PUNCT
aji-171	163	28	are	be	AUX
aji-171	163	29	summarized	summarize	VERB
aji-171	163	30	in	in	ADP
aji-171	163	31	this	this	DET
aji-171	163	32	review	review	NOUN
aji-171	163	33	.	.	PUNCT
aji-171	164	1	it	it	PRON
aji-171	164	2	is	be	AUX
aji-171	164	3	becoming	become	VERB
aji-171	164	4	more	more	ADV
aji-171	164	5	feasible	feasible	ADJ
aji-171	164	6	to	to	PART
aji-171	164	7	find	find	VERB
aji-171	164	8	disease	disease	NOUN
aji-171	164	9	biomarkers	biomarker	NOUN
aji-171	164	10	,	,	PUNCT
aji-171	164	11	even	even	ADV
aji-171	164	12	for	for	ADP
aji-171	164	13	complex	complex	ADJ
aji-171	164	14	conditions	condition	NOUN
aji-171	164	15	like	like	ADP
aji-171	164	16	cancer	cancer	NOUN
aji-171	164	17	,	,	PUNCT
aji-171	164	18	neurodegenerative	neurodegenerative	ADJ
aji-171	164	19	diseases	disease	NOUN
aji-171	164	20	,	,	PUNCT
aji-171	164	21	cardiovascular	cardiovascular	ADJ
aji-171	164	22	diseases	disease	NOUN
aji-171	164	23	,	,	PUNCT
aji-171	164	24	and	and	CCONJ
aji-171	164	25	metabolic	metabolic	NOUN
aji-171	164	26	syndrome	syndrome	NOUN
aji-171	164	27	,	,	PUNCT
aji-171	164	28	thanks	thank	NOUN
aji-171	164	29	to	to	ADP
aji-171	164	30	technological	technological	ADJ
aji-171	164	31	advancements	advancement	NOUN
aji-171	164	32	and	and	CCONJ
aji-171	164	33	metabolomics	metabolomic	NOUN
aji-171	164	34	analysis	analysis	NOUN
aji-171	164	35	capabilities	capability	NOUN
aji-171	164	36	.	.	PUNCT
aji-171	165	1	although	although	SCONJ
aji-171	165	2	early	early	ADJ
aji-171	165	3	diagnosis	diagnosis	NOUN
aji-171	165	4	and	and	CCONJ
aji-171	165	5	classification	classification	NOUN
aji-171	165	6	are	be	AUX
aji-171	165	7	greatly	greatly	ADV
aji-171	165	8	enhanced	enhance	VERB
aji-171	165	9	by	by	ADP
aji-171	165	10	these	these	DET
aji-171	165	11	biomarkers	biomarker	NOUN
aji-171	165	12	,	,	PUNCT
aji-171	165	13	they	they	PRON
aji-171	165	14	also	also	ADV
aji-171	165	15	enable	enable	VERB
aji-171	165	16	a	a	DET
aji-171	165	17	much	much	ADV
aji-171	165	18	more	more	ADV
aji-171	165	19	nuanced	nuanced	ADJ
aji-171	165	20	understanding	understanding	NOUN
aji-171	165	21	of	of	ADP
aji-171	165	22	individual	individual	ADJ
aji-171	165	23	variability	variability	NOUN
aji-171	165	24	in	in	ADP
aji-171	165	25	mamman	mamman	NOUN
aji-171	165	26	et	et	PROPN
aji-171	165	27	al	al	PROPN
aji-171	165	28	.	.	PROPN
aji-171	165	29	;	;	PUNCT
aji-171	166	1	asian	asian	PROPN
aji-171	166	2	j.	j.	PROPN
aji-171	166	3	immunol	immunol	PROPN
aji-171	166	4	.	.	PROPN
aji-171	166	5	,	,	PUNCT
aji-171	166	6	vol	vol	NOUN
aji-171	166	7	.	.	PROPN
aji-171	166	8	8	8	NUM
aji-171	166	9	,	,	PUNCT
aji-171	166	10	no	no	INTJ
aji-171	166	11	.	.	NOUN
aji-171	166	12	1	1	NUM
aji-171	166	13	,	,	PUNCT
aji-171	166	14	pp	pp	ADJ
aji-171	166	15	.	.	PUNCT
aji-171	167	1	190	190	NUM
aji-171	167	2	-	-	SYM
aji-171	167	3	206	206	NUM
aji-171	167	4	,	,	PUNCT
aji-171	167	5	2025	2025	NUM
aji-171	167	6	;	;	PUNCT
aji-171	167	7	article	article	NOUN
aji-171	167	8	no.aji.140476	no.aji.140476	NOUN
aji-171	167	9	193	193	NUM
aji-171	167	10	disease	disease	NOUN
aji-171	167	11	progression	progression	NOUN
aji-171	167	12	and	and	CCONJ
aji-171	167	13	response	response	NOUN
aji-171	167	14	to	to	ADP
aji-171	167	15	treatment	treatment	NOUN
aji-171	167	16	.	.	PUNCT
aji-171	168	1	this	this	DET
aji-171	168	2	review	review	NOUN
aji-171	168	3	's	's	PART
aji-171	168	4	objective	objective	NOUN
aji-171	168	5	is	be	AUX
aji-171	168	6	to	to	PART
aji-171	168	7	examine	examine	VERB
aji-171	168	8	these	these	DET
aji-171	168	9	new	new	ADJ
aji-171	168	10	metabolomics	metabolomic	NOUN
aji-171	168	11	biomarker	biomarker	NOUN
aji-171	168	12	discoveries	discovery	NOUN
aji-171	168	13	with	with	ADP
aji-171	168	14	an	an	DET
aji-171	168	15	emphasis	emphasis	NOUN
aji-171	168	16	on	on	ADP
aji-171	168	17	how	how	SCONJ
aji-171	168	18	they	they	PRON
aji-171	168	19	may	may	AUX
aji-171	168	20	help	help	VERB
aji-171	168	21	with	with	ADP
aji-171	168	22	healthcare	healthcare	NOUN
aji-171	168	23	personalization	personalization	NOUN
aji-171	168	24	.	.	PUNCT
aji-171	169	1	the	the	DET
aji-171	169	2	translational	translational	ADJ
aji-171	169	3	development	development	NOUN
aji-171	169	4	of	of	ADP
aji-171	169	5	metabolomics	metabolomic	NOUN
aji-171	169	6	for	for	ADP
aji-171	169	7	use	use	NOUN
aji-171	169	8	in	in	ADP
aji-171	169	9	mainstream	mainstream	ADJ
aji-171	169	10	clinical	clinical	ADJ
aji-171	169	11	practice	practice	NOUN
aji-171	169	12	is	be	AUX
aji-171	169	13	also	also	ADV
aji-171	169	14	covered	cover	VERB
aji-171	169	15	,	,	PUNCT
aji-171	169	16	with	with	ADP
aji-171	169	17	particular	particular	ADJ
aji-171	169	18	emphasis	emphasis	NOUN
aji-171	169	19	on	on	ADP
aji-171	169	20	how	how	SCONJ
aji-171	169	21	metabolomics	metabolomic	NOUN
aji-171	169	22	can	can	AUX
aji-171	169	23	transform	transform	VERB
aji-171	169	24	healthcare	healthcare	NOUN
aji-171	169	25	from	from	ADP
aji-171	169	26	a	a	DET
aji-171	169	27	one	one	NUM
aji-171	169	28	-	-	PUNCT
aji-171	169	29	size	size	NOUN
aji-171	169	30	-	-	PUNCT
aji-171	169	31	fits	fit	VERB
aji-171	169	32	-	-	PUNCT
aji-171	169	33	all	all	PRON
aji-171	169	34	model	model	NOUN
aji-171	169	35	to	to	ADP
aji-171	169	36	a	a	DET
aji-171	169	37	highly	highly	ADV
aji-171	169	38	individualized	individualized	ADJ
aji-171	169	39	one	one	NUM
aji-171	169	40	where	where	SCONJ
aji-171	169	41	any	any	DET
aji-171	169	42	health	health	NOUN
aji-171	169	43	risk	risk	NOUN
aji-171	169	44	can	can	AUX
aji-171	169	45	be	be	AUX
aji-171	169	46	promptly	promptly	ADV
aji-171	169	47	identified	identify	VERB
aji-171	169	48	and	and	CCONJ
aji-171	169	49	treatment	treatment	NOUN
aji-171	169	50	can	can	AUX
aji-171	169	51	be	be	AUX
aji-171	169	52	tailored	tailor	VERB
aji-171	169	53	for	for	ADP
aji-171	169	54	optimal	optimal	ADJ
aji-171	169	55	efficacy	efficacy	NOUN
aji-171	169	56	.	.	PUNCT
aji-171	170	1	methods	method	NOUN
aji-171	170	2	for	for	ADP
aji-171	170	3	metabolomics	metabolomic	NOUN
aji-171	170	4	research	research	NOUN
aji-171	170	5	:	:	PUNCT
aji-171	170	6	there	there	PRON
aji-171	170	7	are	be	VERB
aji-171	170	8	two	two	NUM
aji-171	170	9	main	main	ADJ
aji-171	170	10	methods	method	NOUN
aji-171	170	11	for	for	ADP
aji-171	170	12	metabolomics	metabolomic	NOUN
aji-171	170	13	research	research	NOUN
aji-171	170	14	:	:	PUNCT
aji-171	170	15	1	1	X
aji-171	170	16	.	.	PUNCT
aji-171	170	17	mass	mass	ADJ
aji-171	170	18	spectrometry	spectrometry	NOUN
aji-171	170	19	(	(	PUNCT
aji-171	170	20	ms)-based	ms)-base	VERB
aji-171	170	21	metabolomics	metabolomic	NOUN
aji-171	170	22	.	.	PUNCT
aji-171	171	1	2	2	X
aji-171	171	2	.	.	X
aji-171	171	3	nuclear	nuclear	ADJ
aji-171	171	4	magnetic	magnetic	ADJ
aji-171	171	5	resonance	resonance	NOUN
aji-171	171	6	(	(	PUNCT
aji-171	171	7	nmr	nmr	NOUN
aji-171	171	8	)	)	PUNCT
aji-171	171	9	spectroscopy	spectroscopy	NOUN
aji-171	171	10	.	.	PUNCT
aji-171	172	1	by	by	ADP
aji-171	172	2	combining	combine	VERB
aji-171	172	3	these	these	DET
aji-171	172	4	methods	method	NOUN
aji-171	172	5	,	,	PUNCT
aji-171	172	6	metabolome	metabolome	ADJ
aji-171	172	7	coverage	coverage	NOUN
aji-171	172	8	can	can	AUX
aji-171	172	9	be	be	AUX
aji-171	172	10	improved	improve	VERB
aji-171	172	11	by	by	ADP
aji-171	172	12	addressing	address	VERB
aji-171	172	13	many	many	ADJ
aji-171	172	14	of	of	ADP
aji-171	172	15	their	their	PRON
aji-171	172	16	individual	individual	ADJ
aji-171	172	17	shortcomings	shortcoming	NOUN
aji-171	172	18	(	(	PUNCT
aji-171	172	19	wilkins	wilkin	NOUN
aji-171	172	20	and	and	CCONJ
aji-171	172	21	trushina	trushina	NOUN
aji-171	172	22	,	,	PUNCT
aji-171	172	23	2018	2018	NUM
aji-171	172	24	)	)	PUNCT
aji-171	172	25	.	.	PUNCT
aji-171	173	1	while	while	SCONJ
aji-171	173	2	nmr	nmr	NOUN
aji-171	173	3	is	be	AUX
aji-171	173	4	useful	useful	ADJ
aji-171	173	5	for	for	ADP
aji-171	173	6	identifying	identify	VERB
aji-171	173	7	core	core	NOUN
aji-171	173	8	metabolites	metabolite	NOUN
aji-171	173	9	in	in	ADP
aji-171	173	10	important	important	ADJ
aji-171	173	11	metabolic	metabolic	NOUN
aji-171	173	12	pathways	pathway	NOUN
aji-171	173	13	,	,	PUNCT
aji-171	173	14	ms	ms	NOUN
aji-171	173	15	-	-	PUNCT
aji-171	173	16	based	base	VERB
aji-171	173	17	metabolomics	metabolomic	NOUN
aji-171	173	18	offers	offer	VERB
aji-171	173	19	a	a	DET
aji-171	173	20	broad	broad	ADJ
aji-171	173	21	metabolite	metabolite	NOUN
aji-171	173	22	coverage	coverage	NOUN
aji-171	173	23	that	that	PRON
aji-171	173	24	includes	include	VERB
aji-171	173	25	polar	polar	ADJ
aji-171	173	26	metabolites	metabolite	NOUN
aji-171	173	27	as	as	ADV
aji-171	173	28	well	well	ADV
aji-171	173	29	as	as	ADP
aji-171	173	30	non	non	ADJ
aji-171	173	31	-	-	ADJ
aji-171	173	32	polar	polar	ADJ
aji-171	173	33	lipids	lipid	NOUN
aji-171	173	34	and	and	CCONJ
aji-171	173	35	is	be	AUX
aji-171	173	36	particularly	particularly	ADV
aji-171	173	37	good	good	ADJ
aji-171	173	38	at	at	ADP
aji-171	173	39	detecting	detect	VERB
aji-171	173	40	low	low	ADJ
aji-171	173	41	-	-	PUNCT
aji-171	173	42	abundance	abundance	NOUN
aji-171	173	43	metabolites	metabolite	NOUN
aji-171	173	44	(	(	PUNCT
aji-171	173	45	wilkins	wilkin	NOUN
aji-171	173	46	and	and	CCONJ
aji-171	173	47	trushina	trushina	NOUN
aji-171	173	48	,	,	PUNCT
aji-171	173	49	2018	2018	NUM
aji-171	173	50	)	)	PUNCT
aji-171	173	51	.	.	PUNCT
aji-171	174	1	additionally	additionally	ADV
aji-171	174	2	,	,	PUNCT
aji-171	174	3	nmr	nmr	NOUN
aji-171	174	4	allows	allow	VERB
aji-171	174	5	for	for	ADP
aji-171	174	6	the	the	DET
aji-171	174	7	study	study	NOUN
aji-171	174	8	of	of	ADP
aji-171	174	9	a	a	DET
aji-171	174	10	large	large	ADJ
aji-171	174	11	number	number	NOUN
aji-171	174	12	of	of	ADP
aji-171	174	13	participants	participant	NOUN
aji-171	174	14	due	due	ADP
aji-171	174	15	to	to	ADP
aji-171	174	16	its	its	PRON
aji-171	174	17	low	low	ADJ
aji-171	174	18	cost	cost	NOUN
aji-171	174	19	,	,	PUNCT
aji-171	174	20	high	high	ADJ
aji-171	174	21	throughput	throughput	NOUN
aji-171	174	22	,	,	PUNCT
aji-171	174	23	and	and	CCONJ
aji-171	174	24	analytical	analytical	ADJ
aji-171	174	25	power	power	NOUN
aji-171	174	26	(	(	PUNCT
aji-171	174	27	surendran	surendran	NOUN
aji-171	174	28	et	et	PROPN
aji-171	174	29	al	al	PROPN
aji-171	174	30	.	.	PROPN
aji-171	174	31	,	,	PUNCT
aji-171	174	32	2022	2022	NUM
aji-171	174	33	)	)	PUNCT
aji-171	174	34	.	.	PUNCT
aji-171	175	1	although	although	SCONJ
aji-171	175	2	the	the	DET
aji-171	175	3	discovery	discovery	NOUN
aji-171	175	4	of	of	ADP
aji-171	175	5	new	new	ADJ
aji-171	175	6	biomarkers	biomarker	NOUN
aji-171	175	7	in	in	ADP
aji-171	175	8	metabolic	metabolic	NOUN
aji-171	175	9	pathways	pathway	NOUN
aji-171	175	10	has	have	AUX
aji-171	175	11	contributed	contribute	VERB
aji-171	175	12	to	to	ADP
aji-171	175	13	the	the	DET
aji-171	175	14	pathogenetic	pathogenetic	ADJ
aji-171	175	15	understanding	understanding	NOUN
aji-171	175	16	of	of	ADP
aji-171	175	17	disease	disease	NOUN
aji-171	175	18	pathways	pathway	NOUN
aji-171	175	19	,	,	PUNCT
aji-171	175	20	untargeted	untargete	VERB
aji-171	175	21	metabolomics	metabolomic	NOUN
aji-171	175	22	has	have	VERB
aji-171	175	23	the	the	DET
aji-171	175	24	potential	potential	NOUN
aji-171	175	25	to	to	PART
aji-171	175	26	identify	identify	VERB
aji-171	175	27	metabolites	metabolite	NOUN
aji-171	175	28	that	that	PRON
aji-171	175	29	may	may	AUX
aji-171	175	30	not	not	PART
aji-171	175	31	be	be	AUX
aji-171	175	32	recognized	recognize	VERB
aji-171	175	33	due	due	ADP
aji-171	175	34	to	to	ADP
aji-171	175	35	their	their	PRON
aji-171	175	36	absence	absence	NOUN
aji-171	175	37	from	from	ADP
aji-171	175	38	the	the	DET
aji-171	175	39	software	software	NOUN
aji-171	175	40	library	library	NOUN
aji-171	175	41	(	(	PUNCT
aji-171	175	42	odom	odom	NOUN
aji-171	175	43	and	and	CCONJ
aji-171	175	44	sutton	sutton	PROPN
aji-171	175	45	,	,	PUNCT
aji-171	175	46	2021	2021	NUM
aji-171	175	47	)	)	PUNCT
aji-171	175	48	.	.	PUNCT
aji-171	176	1	2	2	X
aji-171	176	2	.	.	X
aji-171	176	3	biomarkers	biomarker	NOUN
aji-171	176	4	of	of	ADP
aji-171	176	5	metabolic	metabolic	NOUN
aji-171	176	6	and	and	CCONJ
aji-171	176	7	cardiovascular	cardiovascular	ADJ
aji-171	176	8	diseases	disease	NOUN
aji-171	176	9	using	use	VERB
aji-171	176	10	metabolomics	metabolomic	NOUN
aji-171	176	11	2.1	2.1	NUM
aji-171	176	12	cardiovascular	cardiovascular	ADJ
aji-171	176	13	biomarkers	biomarker	VERB
aji-171	176	14	the	the	DET
aji-171	176	15	metabolomics	metabolomic	NOUN
aji-171	176	16	of	of	ADP
aji-171	176	17	cardiovascular	cardiovascular	ADJ
aji-171	176	18	disease	disease	NOUN
aji-171	176	19	have	have	AUX
aji-171	176	20	identified	identify	VERB
aji-171	176	21	lipid	lipid	NOUN
aji-171	176	22	biomarkers	biomarker	NOUN
aji-171	176	23	and	and	CCONJ
aji-171	176	24	other	other	ADJ
aji-171	176	25	metabolites	metabolite	NOUN
aji-171	176	26	that	that	PRON
aji-171	176	27	describe	describe	VERB
aji-171	176	28	key	key	ADJ
aji-171	176	29	pathophysiological	pathophysiological	ADJ
aji-171	176	30	characteristics	characteristic	NOUN
aji-171	176	31	,	,	PUNCT
aji-171	176	32	such	such	ADJ
aji-171	176	33	as	as	ADP
aji-171	176	34	inflammation	inflammation	NOUN
aji-171	176	35	,	,	PUNCT
aji-171	176	36	oxidative	oxidative	ADJ
aji-171	176	37	stress	stress	NOUN
aji-171	176	38	,	,	PUNCT
aji-171	176	39	and	and	CCONJ
aji-171	176	40	disrupted	disrupt	VERB
aji-171	176	41	lipid	lipid	NOUN
aji-171	176	42	metabolism	metabolism	NOUN
aji-171	176	43	(	(	PUNCT
aji-171	176	44	upadhyay	upadhyay	PROPN
aji-171	176	45	,	,	PUNCT
aji-171	176	46	2015	2015	NUM
aji-171	176	47	;	;	PUNCT
aji-171	176	48	vona	vona	PROPN
aji-171	176	49	et	et	PROPN
aji-171	176	50	al	al	PROPN
aji-171	176	51	.	.	PROPN
aji-171	176	52	,	,	PUNCT
aji-171	176	53	2019	2019	NUM
aji-171	176	54	)	)	PUNCT
aji-171	176	55	.	.	PUNCT
aji-171	177	1	in	in	ADP
aji-171	177	2	addition	addition	NOUN
aji-171	177	3	to	to	ADP
aji-171	177	4	helping	help	VERB
aji-171	177	5	to	to	PART
aji-171	177	6	track	track	VERB
aji-171	177	7	the	the	DET
aji-171	177	8	progression	progression	NOUN
aji-171	177	9	of	of	ADP
aji-171	177	10	the	the	DET
aji-171	177	11	disease	disease	NOUN
aji-171	177	12	,	,	PUNCT
aji-171	177	13	these	these	DET
aji-171	177	14	biomarkers	biomarker	NOUN
aji-171	177	15	have	have	VERB
aji-171	177	16	excellent	excellent	ADJ
aji-171	177	17	diagnostic	diagnostic	ADJ
aji-171	177	18	and	and	CCONJ
aji-171	177	19	prognostic	prognostic	ADJ
aji-171	177	20	values	value	NOUN
aji-171	177	21	for	for	ADP
aji-171	177	22	identifying	identify	VERB
aji-171	177	23	individuals	individual	NOUN
aji-171	177	24	who	who	PRON
aji-171	177	25	are	be	AUX
aji-171	177	26	at	at	ADP
aji-171	177	27	risk	risk	NOUN
aji-171	177	28	of	of	ADP
aji-171	177	29	cardiovascular	cardiovascular	ADJ
aji-171	177	30	diseases	disease	NOUN
aji-171	177	31	(	(	PUNCT
aji-171	177	32	cvd	cvd	NOUN
aji-171	177	33	)	)	PUNCT
aji-171	177	34	.	.	PUNCT
aji-171	178	1	by	by	ADP
aji-171	178	2	offering	offer	VERB
aji-171	178	3	details	detail	NOUN
aji-171	178	4	on	on	ADP
aji-171	178	5	alterations	alteration	NOUN
aji-171	178	6	in	in	ADP
aji-171	178	7	lipid	lipid	ADJ
aji-171	178	8	metabolism	metabolism	NOUN
aji-171	178	9	that	that	PRON
aji-171	178	10	result	result	VERB
aji-171	178	11	in	in	ADP
aji-171	178	12	atherosclerosis	atherosclerosis	NOUN
aji-171	178	13	and	and	CCONJ
aji-171	178	14	cvd	cvd	NOUN
aji-171	178	15	,	,	PUNCT
aji-171	178	16	lipid	lipid	NOUN
aji-171	178	17	biomarkers	biomarker	NOUN
aji-171	178	18	play	play	VERB
aji-171	178	19	a	a	DET
aji-171	178	20	crucial	crucial	ADJ
aji-171	178	21	role	role	NOUN
aji-171	178	22	in	in	ADP
aji-171	178	23	determining	determine	VERB
aji-171	178	24	the	the	DET
aji-171	178	25	risk	risk	NOUN
aji-171	178	26	of	of	ADP
aji-171	178	27	cvd	cvd	PROPN
aji-171	178	28	.	.	PUNCT
aji-171	179	1	higher	high	ADJ
aji-171	179	2	levels	level	NOUN
aji-171	179	3	of	of	ADP
aji-171	179	4	ceramides	ceramide	NOUN
aji-171	179	5	have	have	AUX
aji-171	179	6	been	be	AUX
aji-171	179	7	linked	link	VERB
aji-171	179	8	to	to	ADP
aji-171	179	9	heart	heart	NOUN
aji-171	179	10	failure	failure	NOUN
aji-171	179	11	and	and	CCONJ
aji-171	179	12	atherosclerosis	atherosclerosis	NOUN
aji-171	179	13	(	(	PUNCT
aji-171	179	14	vona	vona	NOUN
aji-171	179	15	et	et	PROPN
aji-171	179	16	al	al	PROPN
aji-171	179	17	.	.	PROPN
aji-171	179	18	,	,	PUNCT
aji-171	179	19	2019	2019	NUM
aji-171	179	20	)	)	PUNCT
aji-171	179	21	,	,	PUNCT
aji-171	179	22	indicating	indicate	VERB
aji-171	179	23	their	their	PRON
aji-171	179	24	involvement	involvement	NOUN
aji-171	179	25	in	in	ADP
aji-171	179	26	inflammatory	inflammatory	ADJ
aji-171	179	27	pathways	pathway	NOUN
aji-171	179	28	and	and	CCONJ
aji-171	179	29	cellular	cellular	ADJ
aji-171	179	30	apoptosis	apoptosis	NOUN
aji-171	179	31	.	.	PUNCT
aji-171	180	1	more	more	ADV
aji-171	180	2	recently	recently	ADV
aji-171	180	3	,	,	PUNCT
aji-171	180	4	certain	certain	ADJ
aji-171	180	5	lipid	lipid	NOUN
aji-171	180	6	metabolites	metabolite	NOUN
aji-171	180	7	have	have	AUX
aji-171	180	8	emerged	emerge	VERB
aji-171	180	9	as	as	ADP
aji-171	180	10	novel	novel	ADJ
aji-171	180	11	biomarkers	biomarker	NOUN
aji-171	180	12	in	in	ADP
aji-171	180	13	atherosclerosis	atherosclerosis	NOUN
aji-171	180	14	.	.	PUNCT
aji-171	181	1	cvd	cvd	PROPN
aji-171	181	2	is	be	AUX
aji-171	181	3	linked	link	VERB
aji-171	181	4	to	to	ADP
aji-171	181	5	other	other	ADJ
aji-171	181	6	non	non	ADJ
aji-171	181	7	-	-	ADJ
aji-171	181	8	lipid	lipid	ADJ
aji-171	181	9	metabolites	metabolite	NOUN
aji-171	181	10	,	,	PUNCT
aji-171	181	11	including	include	VERB
aji-171	181	12	betaine	betaine	NOUN
aji-171	181	13	(	(	PUNCT
aji-171	181	14	millard	millard	PROPN
aji-171	181	15	et	et	PROPN
aji-171	181	16	al	al	PROPN
aji-171	181	17	.	.	PROPN
aji-171	181	18	,	,	PUNCT
aji-171	181	19	2018	2018	NUM
aji-171	181	20	)	)	PUNCT
aji-171	181	21	,	,	PUNCT
aji-171	181	22	branchedchain	branchedchain	NOUN
aji-171	181	23	amino	amino	NOUN
aji-171	181	24	acids	acid	NOUN
aji-171	181	25	(	(	PUNCT
aji-171	181	26	bcaa	bcaa	NOUN
aji-171	181	27	)	)	PUNCT
aji-171	181	28	(	(	PUNCT
aji-171	181	29	doestzada	doestzada	PROPN
aji-171	181	30	et	et	PROPN
aji-171	181	31	al	al	PROPN
aji-171	181	32	.	.	PROPN
aji-171	181	33	,	,	PUNCT
aji-171	181	34	2022	2022	NUM
aji-171	181	35	)	)	PUNCT
aji-171	181	36	,	,	PUNCT
aji-171	181	37	and	and	CCONJ
aji-171	181	38	trimethylamine	trimethylamine	NUM
aji-171	181	39	n	n	CCONJ
aji-171	181	40	-	-	PUNCT
aji-171	181	41	oxide	oxide	NOUN
aji-171	181	42	(	(	PUNCT
aji-171	181	43	tmao	tmao	PROPN
aji-171	181	44	)	)	PUNCT
aji-171	181	45	(	(	PUNCT
aji-171	181	46	park	park	NOUN
aji-171	181	47	et	et	PROPN
aji-171	181	48	al	al	PROPN
aji-171	181	49	.	.	PROPN
aji-171	181	50	,	,	PUNCT
aji-171	181	51	2019	2019	NUM
aji-171	181	52	)	)	PUNCT
aji-171	181	53	.	.	PUNCT
aji-171	182	1	as	as	ADP
aji-171	182	2	a	a	DET
aji-171	182	3	byproduct	byproduct	NOUN
aji-171	182	4	of	of	ADP
aji-171	182	5	the	the	DET
aji-171	182	6	gut	gut	NOUN
aji-171	182	7	microbiota	microbiota	NOUN
aji-171	182	8	's	's	PART
aji-171	182	9	metabolism	metabolism	NOUN
aji-171	182	10	of	of	ADP
aji-171	182	11	carnitine	carnitine	NOUN
aji-171	182	12	and	and	CCONJ
aji-171	182	13	choline	choline	NOUN
aji-171	182	14	,	,	PUNCT
aji-171	182	15	tmao	tmao	PROPN
aji-171	182	16	increases	increase	VERB
aji-171	182	17	the	the	DET
aji-171	182	18	amount	amount	NOUN
aji-171	182	19	of	of	ADP
aji-171	182	20	cholesterol	cholesterol	NOUN
aji-171	182	21	that	that	PRON
aji-171	182	22	deposits	deposit	NOUN
aji-171	182	23	in	in	ADP
aji-171	182	24	arterial	arterial	ADJ
aji-171	182	25	walls	wall	NOUN
aji-171	182	26	,	,	PUNCT
aji-171	182	27	increasing	increase	VERB
aji-171	182	28	the	the	DET
aji-171	182	29	risk	risk	NOUN
aji-171	182	30	of	of	ADP
aji-171	182	31	atherosclerosis	atherosclerosis	NOUN
aji-171	182	32	(	(	PUNCT
aji-171	182	33	fig	fig	NOUN
aji-171	182	34	.	.	NOUN
aji-171	183	1	1	1	NUM
aji-171	183	2	)	)	PUNCT
aji-171	184	1	(	(	PUNCT
aji-171	184	2	zhu	zhu	X
aji-171	184	3	et	et	PROPN
aji-171	184	4	al	al	PROPN
aji-171	184	5	.	.	PROPN
aji-171	184	6	,	,	PUNCT
aji-171	184	7	2020	2020	NUM
aji-171	184	8	)	)	PUNCT
aji-171	184	9	.	.	PUNCT
aji-171	185	1	cardiovascular	cardiovascular	ADJ
aji-171	185	2	problems	problem	NOUN
aji-171	185	3	are	be	AUX
aji-171	185	4	linked	link	VERB
aji-171	185	5	to	to	ADP
aji-171	185	6	elevated	elevated	ADJ
aji-171	185	7	bcaa	bcaa	NOUN
aji-171	185	8	levels	level	NOUN
aji-171	185	9	,	,	PUNCT
aji-171	185	10	which	which	PRON
aji-171	185	11	are	be	AUX
aji-171	185	12	known	know	VERB
aji-171	185	13	to	to	PART
aji-171	185	14	cause	cause	VERB
aji-171	185	15	insulin	insulin	NOUN
aji-171	185	16	resistance	resistance	NOUN
aji-171	185	17	and	and	CCONJ
aji-171	185	18	metabolic	metabolic	NOUN
aji-171	185	19	syndrome	syndrome	NOUN
aji-171	185	20	(	(	PUNCT
aji-171	185	21	lynch	lynch	PROPN
aji-171	185	22	and	and	CCONJ
aji-171	185	23	adams	adams	PROPN
aji-171	185	24	,	,	PUNCT
aji-171	185	25	2014	2014	NUM
aji-171	185	26	)	)	PUNCT
aji-171	185	27	.	.	PUNCT
aji-171	186	1	betaine	betaine	NOUN
aji-171	186	2	may	may	AUX
aji-171	186	3	help	help	VERB
aji-171	186	4	prevent	prevent	VERB
aji-171	186	5	heart	heart	NOUN
aji-171	186	6	disease	disease	NOUN
aji-171	186	7	because	because	SCONJ
aji-171	186	8	it	it	PRON
aji-171	186	9	is	be	AUX
aji-171	186	10	a	a	DET
aji-171	186	11	metabolite	metabolite	NOUN
aji-171	186	12	that	that	PRON
aji-171	186	13	is	be	AUX
aji-171	186	14	involved	involve	VERB
aji-171	186	15	in	in	ADP
aji-171	186	16	the	the	DET
aji-171	186	17	metabolism	metabolism	NOUN
aji-171	186	18	of	of	ADP
aji-171	186	19	homocysteine	homocysteine	NOUN
aji-171	186	20	,	,	PUNCT
aji-171	186	21	which	which	PRON
aji-171	186	22	is	be	AUX
aji-171	186	23	linked	link	VERB
aji-171	186	24	to	to	ADP
aji-171	186	25	improved	improve	VERB
aji-171	186	26	endothelial	endothelial	ADJ
aji-171	186	27	function	function	NOUN
aji-171	186	28	and	and	CCONJ
aji-171	186	29	decreased	decrease	VERB
aji-171	186	30	inflammation	inflammation	NOUN
aji-171	186	31	(	(	PUNCT
aji-171	186	32	zhao	zhao	PROPN
aji-171	186	33	et	et	PROPN
aji-171	186	34	al	al	PROPN
aji-171	186	35	.	.	PROPN
aji-171	186	36	,	,	PUNCT
aji-171	186	37	2018	2018	NUM
aji-171	186	38	)	)	PUNCT
aji-171	186	39	.	.	PUNCT
aji-171	187	1	in	in	ADP
aji-171	187	2	addition	addition	NOUN
aji-171	187	3	to	to	ADP
aji-171	187	4	improving	improve	VERB
aji-171	187	5	cvd	cvd	PROPN
aji-171	187	6	risk	risk	NOUN
aji-171	187	7	prediction	prediction	NOUN
aji-171	187	8	,	,	PUNCT
aji-171	187	9	these	these	DET
aji-171	187	10	biomarkers	biomarker	NOUN
aji-171	187	11	offer	offer	VERB
aji-171	187	12	potential	potential	ADJ
aji-171	187	13	targets	target	NOUN
aji-171	187	14	for	for	ADP
aji-171	187	15	therapeutic	therapeutic	ADJ
aji-171	187	16	intervention	intervention	NOUN
aji-171	187	17	,	,	PUNCT
aji-171	187	18	which	which	PRON
aji-171	187	19	aids	aid	VERB
aji-171	187	20	in	in	ADP
aji-171	187	21	the	the	DET
aji-171	187	22	development	development	NOUN
aji-171	187	23	of	of	ADP
aji-171	187	24	more	more	ADV
aji-171	187	25	individualized	individualized	ADJ
aji-171	187	26	and	and	CCONJ
aji-171	187	27	preventive	preventive	ADJ
aji-171	187	28	strategies	strategy	NOUN
aji-171	187	29	for	for	ADP
aji-171	187	30	cardiovascular	cardiovascular	ADJ
aji-171	187	31	health	health	NOUN
aji-171	187	32	.	.	PUNCT
aji-171	188	1	clinicians	clinician	NOUN
aji-171	188	2	can	can	AUX
aji-171	188	3	better	well	ADV
aji-171	188	4	risk	risk	NOUN
aji-171	188	5	-	-	PUNCT
aji-171	188	6	stratify	stratify	NOUN
aji-171	188	7	patients	patient	NOUN
aji-171	188	8	,	,	PUNCT
aji-171	188	9	track	track	VERB
aji-171	188	10	the	the	DET
aji-171	188	11	course	course	NOUN
aji-171	188	12	of	of	ADP
aji-171	188	13	the	the	DET
aji-171	188	14	disease	disease	NOUN
aji-171	188	15	,	,	PUNCT
aji-171	188	16	and	and	CCONJ
aji-171	188	17	improve	improve	VERB
aji-171	188	18	their	their	PRON
aji-171	188	19	treatment	treatment	NOUN
aji-171	188	20	plans	plan	NOUN
aji-171	188	21	by	by	ADP
aji-171	188	22	characterizing	characterize	VERB
aji-171	188	23	these	these	DET
aji-171	188	24	particular	particular	ADJ
aji-171	188	25	lipid	lipid	NOUN
aji-171	188	26	and	and	CCONJ
aji-171	188	27	metabolic	metabolic	NOUN
aji-171	188	28	biomarkers	biomarker	NOUN
aji-171	188	29	.	.	PUNCT
aji-171	189	1	2.2	2.2	NUM
aji-171	189	2	metabolic	metabolic	NOUN
aji-171	189	3	syndrome	syndrome	NOUN
aji-171	189	4	and	and	CCONJ
aji-171	189	5	diabetes	diabetes	NOUN
aji-171	189	6	in	in	ADP
aji-171	189	7	diabetes	diabetes	NOUN
aji-171	189	8	and	and	CCONJ
aji-171	189	9	metabolic	metabolic	NOUN
aji-171	189	10	syndrome	syndrome	NOUN
aji-171	189	11	,	,	PUNCT
aji-171	189	12	biomarkers	biomarker	NOUN
aji-171	189	13	based	base	VERB
aji-171	189	14	on	on	ADP
aji-171	189	15	metabolomics	metabolomic	NOUN
aji-171	189	16	provide	provide	VERB
aji-171	189	17	information	information	NOUN
aji-171	189	18	about	about	ADP
aji-171	189	19	insulin	insulin	NOUN
aji-171	189	20	resistance	resistance	NOUN
aji-171	189	21	,	,	PUNCT
aji-171	189	22	obesity	obesity	NOUN
aji-171	189	23	,	,	PUNCT
aji-171	189	24	and	and	CCONJ
aji-171	189	25	overall	overall	ADJ
aji-171	189	26	metabolic	metabolic	ADJ
aji-171	189	27	dysfunction	dysfunction	NOUN
aji-171	189	28	that	that	PRON
aji-171	189	29	can	can	AUX
aji-171	189	30	be	be	AUX
aji-171	189	31	linked	link	VERB
aji-171	189	32	to	to	ADP
aji-171	189	33	either	either	PRON
aji-171	189	34	of	of	ADP
aji-171	189	35	these	these	DET
aji-171	189	36	conditions	condition	NOUN
aji-171	189	37	(	(	PUNCT
aji-171	189	38	park	park	NOUN
aji-171	189	39	et	et	NOUN
aji-171	189	40	al	al	PROPN
aji-171	189	41	.	.	PROPN
aji-171	189	42	,	,	PUNCT
aji-171	189	43	2015	2015	NUM
aji-171	189	44	)	)	PUNCT
aji-171	189	45	.	.	PUNCT
aji-171	190	1	indeed	indeed	ADV
aji-171	190	2	,	,	PUNCT
aji-171	190	3	it	it	PRON
aji-171	190	4	has	have	AUX
aji-171	190	5	been	be	AUX
aji-171	190	6	suggested	suggest	VERB
aji-171	190	7	that	that	SCONJ
aji-171	190	8	biomarkers	biomarker	NOUN
aji-171	190	9	improve	improve	VERB
aji-171	190	10	metabolic	metabolic	NOUN
aji-171	190	11	health	health	NOUN
aji-171	190	12	management	management	NOUN
aji-171	190	13	by	by	ADP
aji-171	190	14	enabling	enable	VERB
aji-171	190	15	early	early	ADJ
aji-171	190	16	detection	detection	NOUN
aji-171	190	17	,	,	PUNCT
aji-171	190	18	focused	focused	ADJ
aji-171	190	19	intervention	intervention	NOUN
aji-171	190	20	,	,	PUNCT
aji-171	190	21	and	and	CCONJ
aji-171	190	22	therapeutic	therapeutic	ADJ
aji-171	190	23	response	response	NOUN
aji-171	190	24	monitoring	monitoring	NOUN
aji-171	190	25	.	.	PUNCT
aji-171	191	1	insulin	insulin	NOUN
aji-171	191	2	resistance	resistance	NOUN
aji-171	191	3	and	and	CCONJ
aji-171	191	4	general	general	ADJ
aji-171	191	5	metabolic	metabolic	NOUN
aji-171	191	6	dysfunction	dysfunction	NOUN
aji-171	191	7	are	be	AUX
aji-171	191	8	modulated	modulate	VERB
aji-171	191	9	by	by	ADP
aji-171	191	10	amino	amino	NOUN
aji-171	191	11	acid	acid	NOUN
aji-171	191	12	biomarkers	biomarker	NOUN
aji-171	191	13	(	(	PUNCT
aji-171	191	14	gar	gar	NOUN
aji-171	191	15	et	et	PROPN
aji-171	191	16	al	al	PROPN
aji-171	191	17	.	.	PROPN
aji-171	191	18	,	,	PUNCT
aji-171	191	19	2018	2018	NUM
aji-171	191	20	)	)	PUNCT
aji-171	191	21	.	.	PUNCT
aji-171	192	1	high	high	ADJ
aji-171	192	2	levels	level	NOUN
aji-171	192	3	of	of	ADP
aji-171	192	4	the	the	DET
aji-171	192	5	bcaas	bcaas	NOUN
aji-171	192	6	leucine	leucine	NOUN
aji-171	192	7	,	,	PUNCT
aji-171	192	8	isoleucine	isoleucine	NOUN
aji-171	192	9	,	,	PUNCT
aji-171	192	10	and	and	CCONJ
aji-171	192	11	valine	valine	NOUN
aji-171	192	12	are	be	AUX
aji-171	192	13	frequently	frequently	ADV
aji-171	192	14	linked	link	VERB
aji-171	192	15	to	to	ADP
aji-171	192	16	insulin	insulin	NOUN
aji-171	192	17	resistance	resistance	NOUN
aji-171	192	18	and	and	CCONJ
aji-171	192	19	are	be	AUX
aji-171	192	20	observed	observe	VERB
aji-171	192	21	in	in	ADP
aji-171	192	22	metabolic	metabolic	NOUN
aji-171	192	23	syndrome	syndrome	NOUN
aji-171	192	24	and	and	CCONJ
aji-171	192	25	type	type	NOUN
aji-171	192	26	2	2	NUM
aji-171	192	27	diabetes	diabetes	NOUN
aji-171	192	28	(	(	PUNCT
aji-171	192	29	t2d	t2d	NOUN
aji-171	192	30	)	)	PUNCT
aji-171	192	31	(	(	PUNCT
aji-171	192	32	andersson	andersson	PROPN
aji-171	192	33	-	-	PUNCT
aji-171	192	34	hall	hall	PROPN
aji-171	192	35	et	et	PROPN
aji-171	192	36	al	al	PROPN
aji-171	192	37	.	.	PROPN
aji-171	192	38	,	,	PUNCT
aji-171	192	39	2018	2018	NUM
aji-171	192	40	)	)	PUNCT
aji-171	192	41	.	.	PUNCT
aji-171	193	1	because	because	SCONJ
aji-171	193	2	mamman	mamman	PROPN
aji-171	193	3	et	et	PROPN
aji-171	193	4	al	al	PROPN
aji-171	193	5	.	.	PROPN
aji-171	193	6	;	;	PUNCT
aji-171	193	7	asian	asian	PROPN
aji-171	193	8	j.	j.	PROPN
aji-171	193	9	immunol	immunol	PROPN
aji-171	193	10	.	.	PROPN
aji-171	193	11	,	,	PUNCT
aji-171	193	12	vol	vol	NOUN
aji-171	193	13	.	.	PROPN
aji-171	193	14	8	8	NUM
aji-171	193	15	,	,	PUNCT
aji-171	193	16	no	no	INTJ
aji-171	193	17	.	.	NOUN
aji-171	193	18	1	1	NUM
aji-171	193	19	,	,	PUNCT
aji-171	193	20	pp	pp	ADJ
aji-171	193	21	.	.	PUNCT
aji-171	194	1	190	190	NUM
aji-171	194	2	-	-	SYM
aji-171	194	3	206	206	NUM
aji-171	194	4	,	,	PUNCT
aji-171	194	5	2025	2025	NUM
aji-171	194	6	;	;	PUNCT
aji-171	194	7	article	article	NOUN
aji-171	194	8	no.aji.140476	no.aji.140476	NOUN
aji-171	194	9	194	194	NUM
aji-171	194	10	bcaa	bcaa	NOUN
aji-171	194	11	interferes	interfere	VERB
aji-171	194	12	with	with	ADP
aji-171	194	13	insulin	insulin	NOUN
aji-171	194	14	signaling	signal	VERB
aji-171	194	15	,	,	PUNCT
aji-171	194	16	muscle	muscle	NOUN
aji-171	194	17	cells	cell	NOUN
aji-171	194	18	are	be	AUX
aji-171	194	19	unable	unable	ADJ
aji-171	194	20	to	to	PART
aji-171	194	21	absorb	absorb	VERB
aji-171	194	22	glucose	glucose	NOUN
aji-171	194	23	as	as	ADV
aji-171	194	24	well	well	ADV
aji-171	194	25	as	as	ADP
aji-171	194	26	lipids	lipid	NOUN
aji-171	194	27	build	build	VERB
aji-171	194	28	up	up	ADP
aji-171	194	29	(	(	PUNCT
aji-171	194	30	fig	fig	NOUN
aji-171	194	31	.	.	NOUN
aji-171	195	1	2	2	NUM
aji-171	195	2	)	)	PUNCT
aji-171	195	3	(	(	PUNCT
aji-171	195	4	vanweert	vanweert	NOUN
aji-171	195	5	et	et	PROPN
aji-171	195	6	al	al	PROPN
aji-171	195	7	.	.	PROPN
aji-171	195	8	,	,	PUNCT
aji-171	195	9	2022	2022	NUM
aji-171	195	10	)	)	PUNCT
aji-171	195	11	.	.	PUNCT
aji-171	196	1	fig	fig	NOUN
aji-171	196	2	.	.	PUNCT
aji-171	197	1	1	1	X
aji-171	197	2	.	.	X
aji-171	197	3	tmao	tmao	PROPN
aji-171	197	4	's	's	PART
aji-171	197	5	function	function	NOUN
aji-171	197	6	in	in	ADP
aji-171	197	7	the	the	DET
aji-171	197	8	development	development	NOUN
aji-171	197	9	and	and	CCONJ
aji-171	197	10	formation	formation	NOUN
aji-171	197	11	of	of	ADP
aji-171	197	12	atherosclerotic	atherosclerotic	ADJ
aji-171	197	13	lesions	lesion	NOUN
aji-171	197	14	.	.	PUNCT
aji-171	198	1	high	high	ADJ
aji-171	198	2	levels	level	NOUN
aji-171	198	3	of	of	ADP
aji-171	198	4	tmao	tmao	PROPN
aji-171	198	5	in	in	ADP
aji-171	198	6	the	the	DET
aji-171	198	7	bloodstream	bloodstream	NOUN
aji-171	198	8	are	be	AUX
aji-171	198	9	essential	essential	ADJ
aji-171	198	10	for	for	ADP
aji-171	198	11	the	the	DET
aji-171	198	12	development	development	NOUN
aji-171	198	13	of	of	ADP
aji-171	198	14	foam	foam	NOUN
aji-171	198	15	cells	cell	NOUN
aji-171	198	16	and	and	CCONJ
aji-171	198	17	endothelial	endothelial	ADJ
aji-171	198	18	dysfunction	dysfunction	NOUN
aji-171	198	19	;	;	PUNCT
aji-171	198	20	tmao	tmao	PROPN
aji-171	198	21	can	can	AUX
aji-171	198	22	stimulate	stimulate	VERB
aji-171	198	23	platelets	platelet	NOUN
aji-171	198	24	and	and	CCONJ
aji-171	198	25	encourage	encourage	VERB
aji-171	198	26	the	the	DET
aji-171	198	27	formation	formation	NOUN
aji-171	198	28	of	of	ADP
aji-171	198	29	thrombi	thrombi	NOUN
aji-171	198	30	,	,	PUNCT
aji-171	198	31	which	which	PRON
aji-171	198	32	increases	increase	VERB
aji-171	198	33	the	the	DET
aji-171	198	34	risk	risk	NOUN
aji-171	198	35	of	of	ADP
aji-171	198	36	rupture	rupture	NOUN
aji-171	198	37	of	of	ADP
aji-171	198	38	the	the	DET
aji-171	198	39	atherosclerotic	atherosclerotic	ADJ
aji-171	198	40	plaque	plaque	NOUN
aji-171	198	41	copyright	copyright	NOUN
aji-171	198	42	wiley	wiley	NOUN
aji-171	198	43	(	(	PUNCT
aji-171	198	44	2020	2020	NUM
aji-171	198	45	)	)	PUNCT
aji-171	199	1	(	(	PUNCT
aji-171	199	2	zhu	zhu	X
aji-171	199	3	et	et	PROPN
aji-171	199	4	al	al	PROPN
aji-171	199	5	.	.	PROPN
aji-171	199	6	,	,	PUNCT
aji-171	199	7	2020	2020	NUM
aji-171	199	8	)	)	PUNCT
aji-171	199	9	fig	fig	NOUN
aji-171	199	10	.	.	PUNCT
aji-171	200	1	2	2	X
aji-171	200	2	.	.	X
aji-171	200	3	diagrammatic	diagrammatic	ADJ
aji-171	200	4	representation	representation	NOUN
aji-171	200	5	of	of	ADP
aji-171	200	6	the	the	DET
aji-171	200	7	processes	process	NOUN
aji-171	200	8	that	that	PRON
aji-171	200	9	connect	connect	VERB
aji-171	200	10	insulin	insulin	NOUN
aji-171	200	11	resistance	resistance	NOUN
aji-171	200	12	and	and	CCONJ
aji-171	200	13	bcaa	bcaa	NOUN
aji-171	200	14	catabolism	catabolism	NOUN
aji-171	200	15	.	.	PUNCT
aji-171	201	1	glut4	glut4	NOUN
aji-171	201	2	glucose	glucose	NOUN
aji-171	201	3	transporter	transporter	NOUN
aji-171	201	4	type	type	NOUN
aji-171	201	5	4	4	NUM
aji-171	201	6	,	,	PUNCT
aji-171	201	7	irs-1	irs-1	ADV
aji-171	201	8	insulin	insulin	NOUN
aji-171	201	9	receptor	receptor	NOUN
aji-171	201	10	substrate-1	substrate-1	PROPN
aji-171	201	11	,	,	PUNCT
aji-171	201	12	pdh	pdh	NOUN
aji-171	201	13	pyruvate	pyruvate	NOUN
aji-171	201	14	dehydrogenase	dehydrogenase	NOUN
aji-171	201	15	complex	complex	NOUN
aji-171	201	16	,	,	PUNCT
aji-171	201	17	s6k	s6k	PROPN
aji-171	201	18	ribosomal	ribosomal	PROPN
aji-171	201	19	s6	s6	PROPN
aji-171	201	20	kinase	kinase	PROPN
aji-171	201	21	,	,	PUNCT
aji-171	201	22	mtor	mtor	PROPN
aji-171	201	23	mammalian	mammalian	ADJ
aji-171	201	24	target	target	NOUN
aji-171	201	25	of	of	ADP
aji-171	201	26	rapamycin	rapamycin	NOUN
aji-171	201	27	complex	complex	NOUN
aji-171	201	28	,	,	PUNCT
aji-171	201	29	and	and	CCONJ
aji-171	201	30	bcaa	bcaa	NOUN
aji-171	201	31	branch	branch	NOUN
aji-171	201	32	-	-	PUNCT
aji-171	201	33	chain	chain	NOUN
aji-171	201	34	amino	amino	NOUN
aji-171	201	35	acids	acid	NOUN
aji-171	201	36	.	.	PUNCT
aji-171	202	1	(	(	PUNCT
aji-171	202	2	vanweert	vanweert	NOUN
aji-171	202	3	et	et	PROPN
aji-171	202	4	al	al	PROPN
aji-171	202	5	.	.	PROPN
aji-171	202	6	,	,	PUNCT
aji-171	202	7	2022	2022	NUM
aji-171	202	8	)	)	PUNCT
aji-171	202	9	.	.	PUNCT
aji-171	203	1	copyright	copyright	NOUN
aji-171	203	2	nature	nature	NOUN
aji-171	203	3	publishing	publishing	NOUN
aji-171	203	4	group	group	NOUN
aji-171	203	5	(	(	PUNCT
aji-171	203	6	2022	2022	NUM
aji-171	203	7	)	)	PUNCT
aji-171	203	8	mamman	mamman	NOUN
aji-171	203	9	et	et	PROPN
aji-171	203	10	al	al	PROPN
aji-171	203	11	.	.	PROPN
aji-171	203	12	;	;	PUNCT
aji-171	203	13	asian	asian	PROPN
aji-171	203	14	j.	j.	PROPN
aji-171	203	15	immunol	immunol	PROPN
aji-171	203	16	.	.	PROPN
aji-171	203	17	,	,	PUNCT
aji-171	203	18	vol	vol	NOUN
aji-171	203	19	.	.	PROPN
aji-171	203	20	8	8	NUM
aji-171	203	21	,	,	PUNCT
aji-171	203	22	no	no	INTJ
aji-171	203	23	.	.	NOUN
aji-171	203	24	1	1	NUM
aji-171	203	25	,	,	PUNCT
aji-171	203	26	pp	pp	ADJ
aji-171	203	27	.	.	PUNCT
aji-171	204	1	190	190	NUM
aji-171	204	2	-	-	SYM
aji-171	204	3	206	206	NUM
aji-171	204	4	,	,	PUNCT
aji-171	204	5	2025	2025	NUM
aji-171	204	6	;	;	PUNCT
aji-171	204	7	article	article	NOUN
aji-171	204	8	no.aji.140476	no.aji.140476	X
aji-171	204	9	195	195	NUM
aji-171	205	1	a	a	DET
aji-171	205	2	higher	high	ADJ
aji-171	205	3	risk	risk	NOUN
aji-171	205	4	of	of	ADP
aji-171	205	5	type	type	NOUN
aji-171	205	6	2	2	NUM
aji-171	205	7	diabetes	diabetes	NOUN
aji-171	205	8	has	have	AUX
aji-171	205	9	also	also	ADV
aji-171	205	10	been	be	AUX
aji-171	205	11	linked	link	VERB
aji-171	205	12	to	to	ADP
aji-171	205	13	aromatic	aromatic	ADJ
aji-171	205	14	amino	amino	NOUN
aji-171	205	15	acids	acid	NOUN
aji-171	205	16	like	like	ADP
aji-171	205	17	phenylalanine	phenylalanine	NOUN
aji-171	205	18	and	and	CCONJ
aji-171	205	19	tyrosine	tyrosine	NOUN
aji-171	205	20	,	,	PUNCT
aji-171	205	21	which	which	PRON
aji-171	205	22	are	be	AUX
aji-171	205	23	a	a	DET
aji-171	205	24	sign	sign	NOUN
aji-171	205	25	of	of	ADP
aji-171	205	26	impaired	impaired	ADJ
aji-171	205	27	amino	amino	NOUN
aji-171	205	28	acid	acid	NOUN
aji-171	205	29	metabolism	metabolism	NOUN
aji-171	205	30	in	in	ADP
aji-171	205	31	obesity	obesity	NOUN
aji-171	205	32	and	and	CCONJ
aji-171	205	33	insulin	insulin	NOUN
aji-171	205	34	resistance	resistance	NOUN
aji-171	205	35	(	(	PUNCT
aji-171	205	36	luo	luo	PROPN
aji-171	205	37	et	et	PROPN
aji-171	205	38	al	al	PROPN
aji-171	205	39	.	.	PROPN
aji-171	205	40	,	,	PUNCT
aji-171	205	41	2020	2020	NUM
aji-171	205	42	)	)	PUNCT
aji-171	205	43	.	.	PUNCT
aji-171	206	1	since	since	SCONJ
aji-171	206	2	impaired	impair	VERB
aji-171	206	3	lipid	lipid	NOUN
aji-171	206	4	metabolism	metabolism	NOUN
aji-171	206	5	is	be	AUX
aji-171	206	6	one	one	NUM
aji-171	206	7	of	of	ADP
aji-171	206	8	the	the	DET
aji-171	206	9	factors	factor	NOUN
aji-171	206	10	contributing	contribute	VERB
aji-171	206	11	to	to	ADP
aji-171	206	12	insulin	insulin	NOUN
aji-171	206	13	resistance	resistance	NOUN
aji-171	206	14	and	and	CCONJ
aji-171	206	15	systemic	systemic	ADJ
aji-171	206	16	inflammation	inflammation	NOUN
aji-171	206	17	,	,	PUNCT
aji-171	206	18	lipid	lipid	NOUN
aji-171	206	19	biomarkers	biomarker	NOUN
aji-171	206	20	are	be	AUX
aji-171	206	21	essential	essential	ADJ
aji-171	206	22	in	in	ADP
aji-171	206	23	the	the	DET
aji-171	206	24	development	development	NOUN
aji-171	206	25	of	of	ADP
aji-171	206	26	diabetes	diabetes	NOUN
aji-171	206	27	and	and	CCONJ
aji-171	206	28	metabolic	metabolic	NOUN
aji-171	206	29	syndrome	syndrome	NOUN
aji-171	206	30	.	.	PUNCT
aji-171	207	1	high	high	ADJ
aji-171	207	2	levels	level	NOUN
aji-171	207	3	of	of	ADP
aji-171	207	4	obesity	obesity	NOUN
aji-171	207	5	are	be	AUX
aji-171	207	6	associated	associate	VERB
aji-171	207	7	with	with	ADP
aji-171	207	8	free	free	ADJ
aji-171	207	9	fatty	fatty	NOUN
aji-171	207	10	acids	acid	NOUN
aji-171	207	11	(	(	PUNCT
aji-171	207	12	ffas	ffas	NOUN
aji-171	207	13	)	)	PUNCT
aji-171	207	14	,	,	PUNCT
aji-171	207	15	which	which	PRON
aji-171	207	16	exacerbate	exacerbate	VERB
aji-171	207	17	inflammation	inflammation	NOUN
aji-171	207	18	and	and	CCONJ
aji-171	207	19	insulin	insulin	NOUN
aji-171	207	20	resistance	resistance	NOUN
aji-171	207	21	(	(	PUNCT
aji-171	207	22	marko	marko	PROPN
aji-171	207	23	et	et	PROPN
aji-171	207	24	al	al	PROPN
aji-171	207	25	.	.	PROPN
aji-171	207	26	,	,	PUNCT
aji-171	207	27	2024	2024	NUM
aji-171	207	28	)	)	PUNCT
aji-171	207	29	.	.	PUNCT
aji-171	208	1	according	accord	VERB
aji-171	208	2	to	to	ADP
aji-171	208	3	roszczyc	roszczyc	ADJ
aji-171	208	4	-	-	PUNCT
aji-171	208	5	owsiejczuk	owsiejczuk	NOUN
aji-171	208	6	et	et	NOUN
aji-171	208	7	al	al	PROPN
aji-171	208	8	.	.	PROPN
aji-171	209	1	(	(	PUNCT
aji-171	209	2	2021	2021	NUM
aji-171	209	3	)	)	PUNCT
aji-171	209	4	,	,	PUNCT
aji-171	209	5	ceramides	ceramide	NOUN
aji-171	209	6	,	,	PUNCT
aji-171	209	7	a	a	DET
aji-171	209	8	class	class	NOUN
aji-171	209	9	of	of	ADP
aji-171	209	10	sphingolipids	sphingolipid	NOUN
aji-171	209	11	,	,	PUNCT
aji-171	209	12	are	be	AUX
aji-171	209	13	closely	closely	ADV
aji-171	209	14	linked	link	VERB
aji-171	209	15	to	to	ADP
aji-171	209	16	lipid	lipid	NOUN
aji-171	209	17	-	-	PUNCT
aji-171	209	18	induced	induce	VERB
aji-171	209	19	cellular	cellular	ADJ
aji-171	209	20	stress	stress	NOUN
aji-171	209	21	and	and	CCONJ
aji-171	209	22	apoptosis	apoptosis	NOUN
aji-171	209	23	and	and	CCONJ
aji-171	209	24	are	be	AUX
aji-171	209	25	implicated	implicate	VERB
aji-171	209	26	in	in	ADP
aji-171	209	27	insulin	insulin	NOUN
aji-171	209	28	resistance	resistance	NOUN
aji-171	209	29	.	.	PUNCT
aji-171	210	1	ceramides	ceramide	NOUN
aji-171	210	2	are	be	AUX
aji-171	210	3	a	a	DET
aji-171	210	4	potential	potential	ADJ
aji-171	210	5	target	target	NOUN
aji-171	210	6	for	for	ADP
aji-171	210	7	therapy	therapy	NOUN
aji-171	210	8	because	because	SCONJ
aji-171	210	9	they	they	PRON
aji-171	210	10	are	be	AUX
aji-171	210	11	predictive	predictive	ADJ
aji-171	210	12	of	of	ADP
aji-171	210	13	metabolic	metabolic	ADJ
aji-171	210	14	dysfunction	dysfunction	NOUN
aji-171	210	15	and	and	CCONJ
aji-171	210	16	the	the	DET
aji-171	210	17	onset	onset	NOUN
aji-171	210	18	of	of	ADP
aji-171	210	19	type	type	NOUN
aji-171	210	20	2	2	NUM
aji-171	210	21	diabetes	diabetes	NOUN
aji-171	210	22	(	(	PUNCT
aji-171	210	23	chaurasia	chaurasia	PROPN
aji-171	210	24	et	et	PROPN
aji-171	210	25	al	al	PROPN
aji-171	210	26	.	.	PROPN
aji-171	210	27	,	,	PUNCT
aji-171	210	28	2021	2021	NUM
aji-171	210	29	)	)	PUNCT
aji-171	210	30	.	.	PUNCT
aji-171	211	1	metabolites	metabolite	NOUN
aji-171	211	2	of	of	ADP
aji-171	211	3	the	the	DET
aji-171	211	4	tricarboxylic	tricarboxylic	ADJ
aji-171	211	5	and	and	CCONJ
aji-171	211	6	glycolytic	glycolytic	ADJ
aji-171	211	7	acid	acid	NOUN
aji-171	211	8	cycles	cycle	NOUN
aji-171	211	9	are	be	AUX
aji-171	211	10	examples	example	NOUN
aji-171	211	11	of	of	ADP
aji-171	211	12	additional	additional	ADJ
aji-171	211	13	biomarkers	biomarker	NOUN
aji-171	211	14	.	.	PUNCT
aji-171	212	1	the	the	DET
aji-171	212	2	end	end	NOUN
aji-171	212	3	products	product	NOUN
aji-171	212	4	of	of	ADP
aji-171	212	5	glycolysis	glycolysis	NOUN
aji-171	212	6	,	,	PUNCT
aji-171	212	7	lactate	lactate	NOUN
aji-171	212	8	and	and	CCONJ
aji-171	212	9	pyruvate	pyruvate	NOUN
aji-171	212	10	,	,	PUNCT
aji-171	212	11	have	have	AUX
aji-171	212	12	been	be	AUX
aji-171	212	13	found	find	VERB
aji-171	212	14	to	to	PART
aji-171	212	15	be	be	AUX
aji-171	212	16	elevated	elevate	VERB
aji-171	212	17	in	in	ADP
aji-171	212	18	metabolic	metabolic	NOUN
aji-171	212	19	syndrome	syndrome	NOUN
aji-171	212	20	,	,	PUNCT
aji-171	212	21	indicating	indicate	VERB
aji-171	212	22	a	a	DET
aji-171	212	23	disruption	disruption	NOUN
aji-171	212	24	in	in	ADP
aji-171	212	25	the	the	DET
aji-171	212	26	metabolism	metabolism	NOUN
aji-171	212	27	of	of	ADP
aji-171	212	28	glucose	glucose	NOUN
aji-171	212	29	(	(	PUNCT
aji-171	212	30	rabinowitz	rabinowitz	NOUN
aji-171	212	31	and	and	CCONJ
aji-171	212	32	enerbäck	enerbäck	ADJ
aji-171	212	33	,	,	PUNCT
aji-171	212	34	2020	2020	NUM
aji-171	212	35	)	)	PUNCT
aji-171	212	36	.	.	PUNCT
aji-171	213	1	insulin	insulin	NOUN
aji-171	213	2	resistance	resistance	NOUN
aji-171	213	3	-	-	PUNCT
aji-171	213	4	related	relate	VERB
aji-171	213	5	mitochondrial	mitochondrial	ADJ
aji-171	213	6	dysfunction	dysfunction	NOUN
aji-171	213	7	and	and	CCONJ
aji-171	213	8	elevated	elevated	ADJ
aji-171	213	9	levels	level	NOUN
aji-171	213	10	of	of	ADP
aji-171	213	11	tricarboxylic	tricarboxylic	ADJ
aji-171	213	12	acid	acid	NOUN
aji-171	213	13	cycle	cycle	NOUN
aji-171	213	14	intermediates	intermediate	NOUN
aji-171	213	15	,	,	PUNCT
aji-171	213	16	such	such	ADJ
aji-171	213	17	as	as	ADP
aji-171	213	18	citrate	citrate	NOUN
aji-171	213	19	and	and	CCONJ
aji-171	213	20	succinate	succinate	NOUN
aji-171	213	21	signaling	signaling	NOUN
aji-171	213	22	,	,	PUNCT
aji-171	213	23	have	have	AUX
aji-171	213	24	been	be	AUX
aji-171	213	25	linked	link	VERB
aji-171	213	26	to	to	ADP
aji-171	213	27	disruptions	disruption	NOUN
aji-171	213	28	in	in	ADP
aji-171	213	29	energy	energy	NOUN
aji-171	213	30	metabolism	metabolism	NOUN
aji-171	213	31	in	in	ADP
aji-171	213	32	obese	obese	ADJ
aji-171	213	33	individuals	individual	NOUN
aji-171	213	34	(	(	PUNCT
aji-171	213	35	ives	ive	NOUN
aji-171	213	36	et	et	NOUN
aji-171	213	37	al	al	PROPN
aji-171	213	38	.	.	PROPN
aji-171	213	39	,	,	PUNCT
aji-171	213	40	2020	2020	NUM
aji-171	213	41	)	)	PUNCT
aji-171	213	42	.	.	PUNCT
aji-171	214	1	additionally	additionally	ADV
aji-171	214	2	,	,	PUNCT
aji-171	214	3	biomarkers	biomarker	NOUN
aji-171	214	4	like	like	ADP
aji-171	214	5	these	these	PRON
aji-171	214	6	are	be	AUX
aji-171	214	7	crucial	crucial	ADJ
aji-171	214	8	for	for	ADP
aji-171	214	9	the	the	DET
aji-171	214	10	early	early	ADJ
aji-171	214	11	detection	detection	NOUN
aji-171	214	12	of	of	ADP
aji-171	214	13	metabolic	metabolic	NOUN
aji-171	214	14	diseases	disease	NOUN
aji-171	214	15	and	and	CCONJ
aji-171	214	16	have	have	AUX
aji-171	214	17	bearing	bear	VERB
aji-171	214	18	on	on	ADP
aji-171	214	19	individualized	individualized	ADJ
aji-171	214	20	treatment	treatment	NOUN
aji-171	214	21	plans	plan	NOUN
aji-171	214	22	.	.	PUNCT
aji-171	215	1	in	in	ADP
aji-171	215	2	addition	addition	NOUN
aji-171	215	3	to	to	ADP
aji-171	215	4	identifying	identify	VERB
aji-171	215	5	individuals	individual	NOUN
aji-171	215	6	at	at	ADP
aji-171	215	7	high	high	ADJ
aji-171	215	8	risk	risk	NOUN
aji-171	215	9	for	for	ADP
aji-171	215	10	diabetes	diabetes	NOUN
aji-171	215	11	and	and	CCONJ
aji-171	215	12	metabolic	metabolic	NOUN
aji-171	215	13	syndrome	syndrome	NOUN
aji-171	215	14	,	,	PUNCT
aji-171	215	15	such	such	ADJ
aji-171	215	16	surveillance	surveillance	NOUN
aji-171	215	17	of	of	ADP
aji-171	215	18	particular	particular	ADJ
aji-171	215	19	metabolic	metabolic	NOUN
aji-171	215	20	signatures	signature	NOUN
aji-171	215	21	can	can	AUX
aji-171	215	22	give	give	VERB
aji-171	215	23	clinicians	clinician	NOUN
aji-171	215	24	the	the	DET
aji-171	215	25	ability	ability	NOUN
aji-171	215	26	to	to	PART
aji-171	215	27	track	track	VERB
aji-171	215	28	the	the	DET
aji-171	215	29	progression	progression	NOUN
aji-171	215	30	of	of	ADP
aji-171	215	31	the	the	DET
aji-171	215	32	disease	disease	NOUN
aji-171	215	33	in	in	ADP
aji-171	215	34	real	real	ADJ
aji-171	215	35	time	time	NOUN
aji-171	215	36	,	,	PUNCT
aji-171	215	37	allowing	allow	VERB
aji-171	215	38	them	they	PRON
aji-171	215	39	to	to	PART
aji-171	215	40	adjust	adjust	VERB
aji-171	215	41	their	their	PRON
aji-171	215	42	intervention	intervention	NOUN
aji-171	215	43	to	to	PART
aji-171	215	44	maximize	maximize	VERB
aji-171	215	45	metabolic	metabolic	NOUN
aji-171	215	46	health	health	NOUN
aji-171	215	47	(	(	PUNCT
aji-171	215	48	ives	ive	NOUN
aji-171	215	49	et	et	NOUN
aji-171	215	50	al	al	PROPN
aji-171	215	51	.	.	PROPN
aji-171	215	52	,	,	PUNCT
aji-171	215	53	2020	2020	NUM
aji-171	215	54	)	)	PUNCT
aji-171	215	55	.	.	PUNCT
aji-171	216	1	3	3	X
aji-171	216	2	.	.	X
aji-171	216	3	metabolomics	metabolomic	NOUN
aji-171	216	4	-	-	PUNCT
aji-171	216	5	based	base	VERB
aji-171	216	6	biomarkers	biomarker	NOUN
aji-171	216	7	for	for	ADP
aji-171	216	8	cancer	cancer	NOUN
aji-171	216	9	3.1	3.1	NUM
aji-171	216	10	changes	change	NOUN
aji-171	216	11	in	in	ADP
aji-171	216	12	metabolism	metabolism	NOUN
aji-171	216	13	in	in	ADP
aji-171	216	14	cancer	cancer	NOUN
aji-171	216	15	compared	compare	VERB
aji-171	216	16	to	to	ADP
aji-171	216	17	normal	normal	ADJ
aji-171	216	18	cells	cell	NOUN
aji-171	216	19	,	,	PUNCT
aji-171	216	20	cancer	cancer	NOUN
aji-171	216	21	cells	cell	NOUN
aji-171	216	22	exhibit	exhibit	VERB
aji-171	216	23	significant	significant	ADJ
aji-171	216	24	metabolic	metabolic	NOUN
aji-171	216	25	reprogramming	reprogramme	VERB
aji-171	216	26	that	that	PRON
aji-171	216	27	enables	enable	VERB
aji-171	216	28	them	they	PRON
aji-171	216	29	to	to	PART
aji-171	216	30	invade	invade	VERB
aji-171	216	31	,	,	PUNCT
aji-171	216	32	multiply	multiply	ADV
aji-171	216	33	,	,	PUNCT
aji-171	216	34	and	and	CCONJ
aji-171	216	35	survive	survive	VERB
aji-171	216	36	quickly	quickly	ADV
aji-171	216	37	(	(	PUNCT
aji-171	216	38	schiliro	schiliro	ADJ
aji-171	216	39	and	and	CCONJ
aji-171	216	40	firestein	firestein	ADV
aji-171	216	41	,	,	PUNCT
aji-171	216	42	2021	2021	NUM
aji-171	216	43	)	)	PUNCT
aji-171	216	44	.	.	PUNCT
aji-171	217	1	this	this	DET
aji-171	217	2	type	type	NOUN
aji-171	217	3	of	of	ADP
aji-171	217	4	metabolic	metabolic	NOUN
aji-171	217	5	change	change	NOUN
aji-171	217	6	has	have	AUX
aji-171	217	7	been	be	AUX
aji-171	217	8	referred	refer	VERB
aji-171	217	9	to	to	ADP
aji-171	217	10	as	as	ADP
aji-171	217	11	the	the	DET
aji-171	217	12	"	"	PUNCT
aji-171	217	13	warburg	warburg	NOUN
aji-171	217	14	effect	effect	NOUN
aji-171	217	15	"	"	PUNCT
aji-171	217	16	(	(	PUNCT
aji-171	217	17	liberti	liberti	NOUN
aji-171	217	18	and	and	CCONJ
aji-171	217	19	locasale	locasale	NOUN
aji-171	217	20	,	,	PUNCT
aji-171	217	21	2016	2016	NUM
aji-171	217	22	;	;	PUNCT
aji-171	217	23	deberardinis	deberardinis	PROPN
aji-171	217	24	and	and	CCONJ
aji-171	217	25	chandel	chandel	PROPN
aji-171	217	26	,	,	PUNCT
aji-171	217	27	2020	2020	NUM
aji-171	217	28	)	)	PUNCT
aji-171	217	29	.	.	PUNCT
aji-171	218	1	even	even	ADV
aji-171	218	2	when	when	SCONJ
aji-171	218	3	oxygen	oxygen	NOUN
aji-171	218	4	is	be	AUX
aji-171	218	5	present	present	ADJ
aji-171	218	6	,	,	PUNCT
aji-171	218	7	aerobic	aerobic	ADJ
aji-171	218	8	glycolysis	glycolysis	NOUN
aji-171	218	9	is	be	AUX
aji-171	218	10	preferred	prefer	VERB
aji-171	218	11	over	over	ADP
aji-171	218	12	oxidative	oxidative	ADJ
aji-171	218	13	phosphorylation	phosphorylation	NOUN
aji-171	218	14	.	.	PUNCT
aji-171	219	1	due	due	ADP
aji-171	219	2	to	to	ADP
aji-171	219	3	this	this	DET
aji-171	219	4	process	process	NOUN
aji-171	219	5	,	,	PUNCT
aji-171	219	6	cancer	cancer	NOUN
aji-171	219	7	cells	cell	NOUN
aji-171	219	8	generate	generate	VERB
aji-171	219	9	massive	massive	ADJ
aji-171	219	10	amounts	amount	NOUN
aji-171	219	11	of	of	ADP
aji-171	219	12	lactate	lactate	NOUN
aji-171	219	13	,	,	PUNCT
aji-171	219	14	which	which	PRON
aji-171	219	15	alters	alter	VERB
aji-171	219	16	the	the	DET
aji-171	219	17	tumor	tumor	NOUN
aji-171	219	18	microenvironment	microenvironment	NOUN
aji-171	219	19	's	's	PART
aji-171	219	20	composition	composition	NOUN
aji-171	219	21	and	and	CCONJ
aji-171	219	22	encourages	encourage	VERB
aji-171	219	23	growth	growth	NOUN
aji-171	219	24	and	and	CCONJ
aji-171	219	25	immune	immune	ADJ
aji-171	219	26	evasion	evasion	NOUN
aji-171	219	27	(	(	PUNCT
aji-171	219	28	beloribi	beloribi	NOUN
aji-171	219	29	-	-	PUNCT
aji-171	219	30	djefaflia	djefaflia	NOUN
aji-171	219	31	et	et	NOUN
aji-171	219	32	al	al	PROPN
aji-171	219	33	.	.	PROPN
aji-171	219	34	,	,	PUNCT
aji-171	219	35	2016	2016	NUM
aji-171	219	36	)	)	PUNCT
aji-171	219	37	.	.	PUNCT
aji-171	220	1	furthermore	furthermore	ADV
aji-171	220	2	,	,	PUNCT
aji-171	220	3	in	in	ADP
aji-171	220	4	order	order	NOUN
aji-171	220	5	to	to	PART
aji-171	220	6	maintain	maintain	VERB
aji-171	220	7	high	high	ADJ
aji-171	220	8	cell	cell	NOUN
aji-171	220	9	division	division	NOUN
aji-171	220	10	rates	rate	NOUN
aji-171	220	11	,	,	PUNCT
aji-171	220	12	cancer	cancer	NOUN
aji-171	220	13	cells	cell	NOUN
aji-171	220	14	exhibit	exhibit	VERB
aji-171	220	15	altered	alter	VERB
aji-171	220	16	lipid	lipid	NOUN
aji-171	220	17	metabolism	metabolism	NOUN
aji-171	220	18	,	,	PUNCT
aji-171	220	19	amino	amino	NOUN
aji-171	220	20	acid	acid	NOUN
aji-171	220	21	dependence	dependence	NOUN
aji-171	220	22	(	(	PUNCT
aji-171	220	23	lieu	lieu	PROPN
aji-171	220	24	et	et	PROPN
aji-171	220	25	al	al	PROPN
aji-171	220	26	.	.	PROPN
aji-171	220	27	,	,	PUNCT
aji-171	220	28	2020	2020	NUM
aji-171	220	29	)	)	PUNCT
aji-171	220	30	,	,	PUNCT
aji-171	220	31	and	and	CCONJ
aji-171	220	32	increased	increase	VERB
aji-171	220	33	nucleotide	nucleotide	ADJ
aji-171	220	34	synthesis	synthesis	NOUN
aji-171	220	35	(	(	PUNCT
aji-171	220	36	mullen	mullen	NOUN
aji-171	220	37	and	and	CCONJ
aji-171	220	38	singh	singh	NOUN
aji-171	220	39	,	,	PUNCT
aji-171	220	40	2023	2023	NUM
aji-171	220	41	)	)	PUNCT
aji-171	220	42	.	.	PUNCT
aji-171	221	1	for	for	ADP
aji-171	221	2	identifying	identify	VERB
aji-171	221	3	specific	specific	ADJ
aji-171	221	4	biomarkers	biomarker	NOUN
aji-171	221	5	linked	link	VERB
aji-171	221	6	to	to	ADP
aji-171	221	7	these	these	DET
aji-171	221	8	specific	specific	ADJ
aji-171	221	9	cancer	cancer	NOUN
aji-171	221	10	changes	change	NOUN
aji-171	221	11	in	in	ADP
aji-171	221	12	metabolism	metabolism	NOUN
aji-171	221	13	,	,	PUNCT
aji-171	221	14	metabolomics	metabolomic	NOUN
aji-171	221	15	has	have	AUX
aji-171	221	16	proven	prove	VERB
aji-171	221	17	to	to	PART
aji-171	221	18	be	be	AUX
aji-171	221	19	very	very	ADV
aji-171	221	20	helpful	helpful	ADJ
aji-171	221	21	.	.	PUNCT
aji-171	222	1	according	accord	VERB
aji-171	222	2	to	to	ADP
aji-171	222	3	danzi	danzi	PROPN
aji-171	222	4	et	et	PROPN
aji-171	222	5	al	al	PROPN
aji-171	222	6	.	.	PROPN
aji-171	223	1	(	(	PUNCT
aji-171	223	2	2023	2023	NUM
aji-171	223	3	)	)	PUNCT
aji-171	223	4	,	,	PUNCT
aji-171	223	5	metabolomics	metabolomic	NOUN
aji-171	223	6	profiling	profiling	NOUN
aji-171	223	7	of	of	ADP
aji-171	223	8	metabolites	metabolite	NOUN
aji-171	223	9	in	in	ADP
aji-171	223	10	blood	blood	NOUN
aji-171	223	11	,	,	PUNCT
aji-171	223	12	tissue	tissue	NOUN
aji-171	223	13	,	,	PUNCT
aji-171	223	14	and	and	CCONJ
aji-171	223	15	other	other	ADJ
aji-171	223	16	biofluids	biofluid	NOUN
aji-171	223	17	reveals	reveal	VERB
aji-171	223	18	metabolic	metabolic	NOUN
aji-171	223	19	signatures	signature	NOUN
aji-171	223	20	linked	link	VERB
aji-171	223	21	to	to	ADP
aji-171	223	22	cancer	cancer	NOUN
aji-171	223	23	that	that	PRON
aji-171	223	24	can	can	AUX
aji-171	223	25	differentiate	differentiate	VERB
aji-171	223	26	cancerous	cancerous	ADJ
aji-171	223	27	cells	cell	NOUN
aji-171	223	28	from	from	ADP
aji-171	223	29	healthy	healthy	ADJ
aji-171	223	30	cells	cell	NOUN
aji-171	223	31	.	.	PUNCT
aji-171	224	1	some	some	DET
aji-171	224	2	oncometabolites	oncometabolite	NOUN
aji-171	224	3	,	,	PUNCT
aji-171	224	4	like	like	ADP
aji-171	224	5	fumarate	fumarate	NOUN
aji-171	224	6	,	,	PUNCT
aji-171	224	7	succinate	succinate	NOUN
aji-171	224	8	,	,	PUNCT
aji-171	224	9	and	and	CCONJ
aji-171	224	10	2	2	NUM
aji-171	224	11	-	-	PUNCT
aji-171	224	12	hydroxyglutarate	hydroxyglutarate	NOUN
aji-171	224	13	(	(	PUNCT
aji-171	224	14	2	2	NUM
aji-171	224	15	-	-	PUNCT
aji-171	224	16	hg	hg	NOUN
aji-171	224	17	)	)	PUNCT
aji-171	224	18	in	in	ADP
aji-171	224	19	gliomas	glioma	NOUN
aji-171	224	20	,	,	PUNCT
aji-171	224	21	act	act	VERB
aji-171	224	22	as	as	ADP
aji-171	224	23	genetic	genetic	ADJ
aji-171	224	24	mutations	mutation	NOUN
aji-171	224	25	in	in	ADP
aji-171	224	26	metabolic	metabolic	NOUN
aji-171	224	27	enzymes	enzyme	NOUN
aji-171	224	28	in	in	ADP
aji-171	224	29	addition	addition	NOUN
aji-171	224	30	to	to	ADP
aji-171	224	31	being	be	AUX
aji-171	224	32	biomarkers	biomarker	NOUN
aji-171	224	33	for	for	ADP
aji-171	224	34	particular	particular	ADJ
aji-171	224	35	types	type	NOUN
aji-171	224	36	of	of	ADP
aji-171	224	37	cancer	cancer	NOUN
aji-171	224	38	(	(	PUNCT
aji-171	224	39	sciacovelli	sciacovelli	NOUN
aji-171	224	40	and	and	CCONJ
aji-171	224	41	frezza	frezza	NOUN
aji-171	224	42	,	,	PUNCT
aji-171	224	43	2016	2016	NUM
aji-171	224	44	;	;	PUNCT
aji-171	224	45	liu	liu	PROPN
aji-171	224	46	and	and	CCONJ
aji-171	224	47	yang	yang	PROPN
aji-171	224	48	,	,	PUNCT
aji-171	224	49	2021	2021	NUM
aji-171	224	50	)	)	PUNCT
aji-171	224	51	.	.	PUNCT
aji-171	225	1	potential	potential	ADJ
aji-171	225	2	treatment	treatment	NOUN
aji-171	225	3	targets	target	NOUN
aji-171	225	4	are	be	AUX
aji-171	225	5	revealed	reveal	VERB
aji-171	225	6	by	by	ADP
aji-171	225	7	these	these	DET
aji-171	225	8	tumor	tumor	NOUN
aji-171	225	9	-	-	PUNCT
aji-171	225	10	specific	specific	ADJ
aji-171	225	11	metabolites	metabolite	NOUN
aji-171	225	12	,	,	PUNCT
aji-171	225	13	which	which	PRON
aji-171	225	14	provide	provide	VERB
aji-171	225	15	insight	insight	NOUN
aji-171	225	16	into	into	ADP
aji-171	225	17	tumor	tumor	NOUN
aji-171	225	18	metabolism	metabolism	NOUN
aji-171	225	19	.	.	PUNCT
aji-171	226	1	additionally	additionally	ADV
aji-171	226	2	,	,	PUNCT
aji-171	226	3	the	the	DET
aji-171	226	4	biomarkers	biomarker	NOUN
aji-171	226	5	obtained	obtain	VERB
aji-171	226	6	through	through	ADP
aji-171	226	7	metabolomics	metabolomic	NOUN
aji-171	226	8	enable	enable	VERB
aji-171	226	9	the	the	DET
aji-171	226	10	advancement	advancement	NOUN
aji-171	226	11	of	of	ADP
aji-171	226	12	personalized	personalized	ADJ
aji-171	226	13	and	and	CCONJ
aji-171	226	14	precision	precision	NOUN
aji-171	226	15	oncology	oncology	NOUN
aji-171	226	16	by	by	ADP
aji-171	226	17	facilitating	facilitate	VERB
aji-171	226	18	early	early	ADJ
aji-171	226	19	cancer	cancer	NOUN
aji-171	226	20	diagnosis	diagnosis	NOUN
aji-171	226	21	,	,	PUNCT
aji-171	226	22	treatment	treatment	NOUN
aji-171	226	23	response	response	NOUN
aji-171	226	24	,	,	PUNCT
aji-171	226	25	and	and	CCONJ
aji-171	226	26	disease	disease	NOUN
aji-171	226	27	surveillance	surveillance	NOUN
aji-171	226	28	(	(	PUNCT
aji-171	226	29	mateo	mateo	PROPN
aji-171	226	30	et	et	PROPN
aji-171	226	31	al	al	PROPN
aji-171	226	32	.	.	PROPN
aji-171	226	33	,	,	PUNCT
aji-171	226	34	2022	2022	NUM
aji-171	226	35	)	)	PUNCT
aji-171	226	36	.	.	PUNCT
aji-171	227	1	through	through	ADP
aji-171	227	2	metabolomics	metabolomic	NOUN
aji-171	227	3	,	,	PUNCT
aji-171	227	4	this	this	PRON
aji-171	227	5	gives	give	VERB
aji-171	227	6	physicians	physician	NOUN
aji-171	227	7	the	the	DET
aji-171	227	8	ability	ability	NOUN
aji-171	227	9	to	to	PART
aji-171	227	10	see	see	VERB
aji-171	227	11	how	how	SCONJ
aji-171	227	12	cancer	cancer	NOUN
aji-171	227	13	cells	cell	NOUN
aji-171	227	14	alter	alter	VERB
aji-171	227	15	their	their	PRON
aji-171	227	16	metabolic	metabolic	NOUN
aji-171	227	17	activity	activity	NOUN
aji-171	227	18	in	in	ADP
aji-171	227	19	real	real	ADJ
aji-171	227	20	time	time	NOUN
aji-171	227	21	as	as	SCONJ
aji-171	227	22	a	a	DET
aji-171	227	23	treatment	treatment	NOUN
aji-171	227	24	progresses	progress	VERB
aji-171	227	25	;	;	PUNCT
aji-171	227	26	as	as	ADP
aji-171	227	27	a	a	DET
aji-171	227	28	result	result	NOUN
aji-171	227	29	,	,	PUNCT
aji-171	227	30	these	these	DET
aji-171	227	31	facts	fact	NOUN
aji-171	227	32	open	open	VERB
aji-171	227	33	the	the	DET
aji-171	227	34	door	door	NOUN
aji-171	227	35	to	to	ADP
aji-171	227	36	targeted	target	VERB
aji-171	227	37	interventions	intervention	NOUN
aji-171	227	38	and	and	CCONJ
aji-171	227	39	individualized	individualized	ADJ
aji-171	227	40	therapeutic	therapeutic	ADJ
aji-171	227	41	approaches	approach	NOUN
aji-171	227	42	.	.	PUNCT
aji-171	228	1	3.2	3.2	NUM
aji-171	228	2	important	important	ADJ
aji-171	228	3	biomarkers	biomarker	NOUN
aji-171	228	4	in	in	ADP
aji-171	228	5	cancer	cancer	NOUN
aji-171	228	6	in	in	ADP
aji-171	228	7	cancer	cancer	NOUN
aji-171	228	8	diagnosis	diagnosis	NOUN
aji-171	228	9	,	,	PUNCT
aji-171	228	10	prognosis	prognosis	NOUN
aji-171	228	11	,	,	PUNCT
aji-171	228	12	and	and	CCONJ
aji-171	228	13	treatment	treatment	NOUN
aji-171	228	14	targeting	targeting	NOUN
aji-171	228	15	,	,	PUNCT
aji-171	228	16	biomarkers	biomarker	NOUN
aji-171	228	17	particularly	particularly	ADV
aji-171	228	18	oncometabolites	oncometabolite	NOUN
aji-171	228	19	are	be	AUX
aji-171	228	20	important	important	ADJ
aji-171	228	21	(	(	PUNCT
aji-171	228	22	kes	kes	PROPN
aji-171	228	23	et	et	PROPN
aji-171	228	24	al	al	PROPN
aji-171	228	25	.	.	PROPN
aji-171	228	26	,	,	PUNCT
aji-171	228	27	2020	2020	NUM
aji-171	228	28	)	)	PUNCT
aji-171	228	29	.	.	PUNCT
aji-171	229	1	mostly	mostly	ADV
aji-171	229	2	caused	cause	VERB
aji-171	229	3	by	by	ADP
aji-171	229	4	mutations	mutation	NOUN
aji-171	229	5	in	in	ADP
aji-171	229	6	metabolic	metabolic	NOUN
aji-171	229	7	enzymes	enzyme	NOUN
aji-171	229	8	,	,	PUNCT
aji-171	229	9	oncometabolites	oncometabolite	NOUN
aji-171	229	10	are	be	AUX
aji-171	229	11	metabolic	metabolic	NOUN
aji-171	229	12	intermediates	intermediate	NOUN
aji-171	229	13	that	that	PRON
aji-171	229	14	,	,	PUNCT
aji-171	229	15	when	when	SCONJ
aji-171	229	16	present	present	ADJ
aji-171	229	17	in	in	ADP
aji-171	229	18	abnormal	abnormal	ADJ
aji-171	229	19	amounts	amount	NOUN
aji-171	229	20	,	,	PUNCT
aji-171	229	21	cause	cause	VERB
aji-171	229	22	neoplastic	neoplastic	ADJ
aji-171	229	23	disease	disease	NOUN
aji-171	229	24	(	(	PUNCT
aji-171	229	25	yong	yong	PROPN
aji-171	229	26	et	et	PROPN
aji-171	229	27	al	al	PROPN
aji-171	229	28	.	.	PROPN
aji-171	229	29	,	,	PUNCT
aji-171	229	30	2020	2020	NUM
aji-171	229	31	)	)	PUNCT
aji-171	229	32	.	.	PUNCT
aji-171	230	1	in	in	ADP
aji-171	230	2	general	general	ADJ
aji-171	230	3	,	,	PUNCT
aji-171	230	4	these	these	DET
aji-171	230	5	biomarkers	biomarker	NOUN
aji-171	230	6	are	be	AUX
aji-171	230	7	extremely	extremely	ADV
aji-171	230	8	valuable	valuable	ADJ
aji-171	230	9	for	for	ADP
aji-171	230	10	predicting	predict	VERB
aji-171	230	11	disease	disease	NOUN
aji-171	230	12	outcomes	outcome	NOUN
aji-171	230	13	and	and	CCONJ
aji-171	230	14	treatment	treatment	NOUN
aji-171	230	15	response	response	NOUN
aji-171	230	16	in	in	ADP
aji-171	230	17	addition	addition	NOUN
aji-171	230	18	to	to	ADP
aji-171	230	19	being	be	AUX
aji-171	230	20	used	use	VERB
aji-171	230	21	to	to	PART
aji-171	230	22	identify	identify	VERB
aji-171	230	23	cancers	cancer	NOUN
aji-171	230	24	.	.	PUNCT
aji-171	231	1	mutations	mutation	NOUN
aji-171	231	2	in	in	ADP
aji-171	231	3	the	the	DET
aji-171	231	4	isocitrate	isocitrate	ADJ
aji-171	231	5	dehydrogenase	dehydrogenase	NOUN
aji-171	231	6	1	1	NUM
aji-171	231	7	(	(	PUNCT
aji-171	231	8	idh1	idh1	PROPN
aji-171	231	9	)	)	PUNCT
aji-171	231	10	and	and	CCONJ
aji-171	231	11	2	2	NUM
aji-171	231	12	(	(	PUNCT
aji-171	231	13	idh2	idh2	PROPN
aji-171	231	14	)	)	PUNCT
aji-171	231	15	enzymes	enzyme	NOUN
aji-171	231	16	in	in	ADP
aji-171	231	17	gliomas	glioma	NOUN
aji-171	231	18	and	and	CCONJ
aji-171	231	19	acute	acute	ADJ
aji-171	231	20	myeloid	myeloid	NOUN
aji-171	231	21	leukemia	leukemia	NOUN
aji-171	231	22	mamman	mamman	NOUN
aji-171	231	23	et	et	PROPN
aji-171	231	24	al	al	PROPN
aji-171	231	25	.	.	PROPN
aji-171	231	26	;	;	PUNCT
aji-171	231	27	asian	asian	PROPN
aji-171	231	28	j.	j.	PROPN
aji-171	231	29	immunol	immunol	PROPN
aji-171	231	30	.	.	PROPN
aji-171	231	31	,	,	PUNCT
aji-171	231	32	vol	vol	NOUN
aji-171	231	33	.	.	PROPN
aji-171	231	34	8	8	NUM
aji-171	231	35	,	,	PUNCT
aji-171	231	36	no	no	INTJ
aji-171	231	37	.	.	NOUN
aji-171	231	38	1	1	NUM
aji-171	231	39	,	,	PUNCT
aji-171	231	40	pp	pp	ADJ
aji-171	231	41	.	.	PUNCT
aji-171	232	1	190	190	NUM
aji-171	232	2	-	-	SYM
aji-171	232	3	206	206	NUM
aji-171	232	4	,	,	PUNCT
aji-171	232	5	2025	2025	NUM
aji-171	232	6	;	;	PUNCT
aji-171	232	7	article	article	NOUN
aji-171	232	8	no.aji.140476	no.aji.140476	NOUN
aji-171	232	9	196	196	NUM
aji-171	232	10	(	(	PUNCT
aji-171	232	11	aml	aml	PROPN
aji-171	232	12	)	)	PUNCT
aji-171	232	13	(	(	PUNCT
aji-171	232	14	fig	fig	NOUN
aji-171	232	15	.	.	NOUN
aji-171	232	16	1	1	X
aji-171	232	17	)	)	PUNCT
aji-171	232	18	produce	produce	VERB
aji-171	232	19	2	2	NUM
aji-171	232	20	-	-	PUNCT
aji-171	232	21	hg	hg	NOUN
aji-171	232	22	,	,	PUNCT
aji-171	232	23	a	a	DET
aji-171	232	24	well	well	ADV
aji-171	232	25	-	-	PUNCT
aji-171	232	26	known	know	VERB
aji-171	232	27	oncometabolite	oncometabolite	NOUN
aji-171	232	28	(	(	PUNCT
aji-171	232	29	rakheja	rakheja	ADV
aji-171	232	30	et	et	PROPN
aji-171	232	31	al	al	PROPN
aji-171	232	32	.	.	PROPN
aji-171	232	33	,	,	PUNCT
aji-171	232	34	2013	2013	NUM
aji-171	232	35	)	)	PUNCT
aji-171	232	36	.	.	PUNCT
aji-171	233	1	because	because	SCONJ
aji-171	233	2	2	2	NUM
aji-171	233	3	-	-	PUNCT
aji-171	233	4	hg	hg	NOUN
aji-171	233	5	is	be	AUX
aji-171	233	6	a	a	DET
aji-171	233	7	factor	factor	NOUN
aji-171	233	8	that	that	PRON
aji-171	233	9	damages	damage	VERB
aji-171	233	10	cellular	cellular	ADJ
aji-171	233	11	differentiation	differentiation	NOUN
aji-171	233	12	at	at	ADP
aji-171	233	13	high	high	ADJ
aji-171	233	14	levels	level	NOUN
aji-171	233	15	,	,	PUNCT
aji-171	233	16	which	which	PRON
aji-171	233	17	leads	lead	VERB
aji-171	233	18	to	to	ADP
aji-171	233	19	tumorigenesis	tumorigenesis	NOUN
aji-171	233	20	,	,	PUNCT
aji-171	233	21	high	high	ADJ
aji-171	233	22	levels	level	NOUN
aji-171	233	23	of	of	ADP
aji-171	233	24	2	2	NUM
aji-171	233	25	-	-	PUNCT
aji-171	233	26	hg	hg	NOUN
aji-171	233	27	function	function	NOUN
aji-171	233	28	as	as	ADP
aji-171	233	29	both	both	CCONJ
aji-171	233	30	a	a	DET
aji-171	233	31	diagnostic	diagnostic	ADJ
aji-171	233	32	and	and	CCONJ
aji-171	233	33	a	a	DET
aji-171	233	34	prognostic	prognostic	ADJ
aji-171	233	35	biomarker	biomarker	NOUN
aji-171	233	36	(	(	PUNCT
aji-171	233	37	wang	wang	PROPN
aji-171	233	38	et	et	PROPN
aji-171	233	39	al	al	PROPN
aji-171	233	40	.	.	PROPN
aji-171	233	41	,	,	PUNCT
aji-171	233	42	2013	2013	NUM
aji-171	233	43	)	)	PUNCT
aji-171	233	44	.	.	PUNCT
aji-171	234	1	for	for	ADP
aji-171	234	2	example	example	NOUN
aji-171	234	3	,	,	PUNCT
aji-171	234	4	dinardo	dinardo	PROPN
aji-171	234	5	et	et	PROPN
aji-171	234	6	al	al	PROPN
aji-171	234	7	.	.	PROPN
aji-171	234	8	2013	2013	NUM
aji-171	234	9	emphasize	emphasize	VERB
aji-171	234	10	the	the	DET
aji-171	234	11	value	value	NOUN
aji-171	234	12	of	of	ADP
aji-171	234	13	2	2	NUM
aji-171	234	14	-	-	PUNCT
aji-171	234	15	hg	hg	NOUN
aji-171	234	16	in	in	ADP
aji-171	234	17	aml	aml	NOUN
aji-171	234	18	for	for	ADP
aji-171	234	19	both	both	DET
aji-171	234	20	diagnosis	diagnosis	NOUN
aji-171	234	21	and	and	CCONJ
aji-171	234	22	prognosis	prognosis	NOUN
aji-171	234	23	(	(	PUNCT
aji-171	234	24	dinardo	dinardo	NOUN
aji-171	234	25	et	et	PROPN
aji-171	234	26	al	al	PROPN
aji-171	234	27	.	.	PROPN
aji-171	234	28	,	,	PUNCT
aji-171	234	29	2013	2013	NUM
aji-171	234	30	)	)	PUNCT
aji-171	234	31	.	.	PUNCT
aji-171	235	1	this	this	DET
aji-171	235	2	study	study	NOUN
aji-171	235	3	showed	show	VERB
aji-171	235	4	that	that	SCONJ
aji-171	235	5	idh1	idh1	PROPN
aji-171	235	6	and	and	CCONJ
aji-171	235	7	idh2	idh2	PROPN
aji-171	235	8	mutations	mutation	NOUN
aji-171	235	9	were	be	AUX
aji-171	235	10	linked	link	VERB
aji-171	235	11	to	to	ADP
aji-171	235	12	significantly	significantly	ADV
aji-171	235	13	elevated	elevate	VERB
aji-171	235	14	serum	serum	NOUN
aji-171	235	15	2	2	NUM
aji-171	235	16	-	-	PUNCT
aji-171	235	17	hg	hg	NOUN
aji-171	235	18	levels	level	NOUN
aji-171	235	19	,	,	PUNCT
aji-171	235	20	and	and	CCONJ
aji-171	235	21	at	at	ADP
aji-171	235	22	a	a	DET
aji-171	235	23	threshold	threshold	NOUN
aji-171	235	24	of	of	ADP
aji-171	235	25	700	700	NUM
aji-171	235	26	ng	ng	NOUN
aji-171	235	27	/	/	SYM
aji-171	235	28	ml	ml	PROPN
aji-171	235	29	,	,	PUNCT
aji-171	235	30	the	the	DET
aji-171	235	31	diagnostic	diagnostic	ADJ
aji-171	235	32	sensitivity	sensitivity	NOUN
aji-171	235	33	and	and	CCONJ
aji-171	235	34	specificity	specificity	NOUN
aji-171	235	35	were	be	AUX
aji-171	235	36	high	high	ADJ
aji-171	235	37	,	,	PUNCT
aji-171	235	38	at	at	ADP
aji-171	235	39	86.9	86.9	NUM
aji-171	235	40	%	%	NOUN
aji-171	235	41	and	and	CCONJ
aji-171	235	42	90.7	90.7	NUM
aji-171	235	43	%	%	NOUN
aji-171	235	44	,	,	PUNCT
aji-171	235	45	respectively	respectively	ADV
aji-171	235	46	.	.	PUNCT
aji-171	236	1	clinical	clinical	ADJ
aji-171	236	2	outcomes	outcome	NOUN
aji-171	236	3	were	be	AUX
aji-171	236	4	also	also	ADV
aji-171	236	5	linked	link	VERB
aji-171	236	6	to	to	PART
aji-171	236	7	serum	serum	VERB
aji-171	236	8	2hg	2hg	ADJ
aji-171	236	9	levels	level	NOUN
aji-171	236	10	,	,	PUNCT
aji-171	236	11	with	with	ADP
aji-171	236	12	higher	high	ADJ
aji-171	236	13	levels	level	NOUN
aji-171	236	14	being	be	AUX
aji-171	236	15	associated	associate	VERB
aji-171	236	16	with	with	ADP
aji-171	236	17	a	a	DET
aji-171	236	18	worse	bad	ADJ
aji-171	236	19	prognosis	prognosis	NOUN
aji-171	236	20	and	and	CCONJ
aji-171	236	21	a	a	DET
aji-171	236	22	greater	great	ADJ
aji-171	236	23	tumor	tumor	NOUN
aji-171	236	24	burden	burden	NOUN
aji-171	236	25	.	.	PUNCT
aji-171	237	1	the	the	DET
aji-171	237	2	results	result	NOUN
aji-171	237	3	suggest	suggest	VERB
aji-171	237	4	that	that	SCONJ
aji-171	237	5	2	2	NUM
aji-171	237	6	-	-	PUNCT
aji-171	237	7	hg	hg	NOUN
aji-171	237	8	may	may	AUX
aji-171	237	9	be	be	AUX
aji-171	237	10	a	a	DET
aji-171	237	11	promising	promising	ADJ
aji-171	237	12	non	non	ADJ
aji-171	237	13	-	-	ADJ
aji-171	237	14	invasive	invasive	ADJ
aji-171	237	15	biomarker	biomarker	NOUN
aji-171	237	16	for	for	ADP
aji-171	237	17	detecting	detect	VERB
aji-171	237	18	idh	idh	NOUN
aji-171	237	19	mutations	mutation	NOUN
aji-171	237	20	and	and	CCONJ
aji-171	237	21	tracking	track	VERB
aji-171	237	22	the	the	DET
aji-171	237	23	progression	progression	NOUN
aji-171	237	24	of	of	ADP
aji-171	237	25	the	the	DET
aji-171	237	26	disease	disease	NOUN
aji-171	237	27	and	and	CCONJ
aji-171	237	28	response	response	NOUN
aji-171	237	29	to	to	ADP
aji-171	237	30	treatment	treatment	NOUN
aji-171	237	31	in	in	ADP
aji-171	237	32	aml	aml	NOUN
aji-171	237	33	patients	patient	NOUN
aji-171	237	34	.	.	PUNCT
aji-171	238	1	giving	give	VERB
aji-171	238	2	some	some	DET
aji-171	238	3	methodological	methodological	ADJ
aji-171	238	4	or	or	CCONJ
aji-171	238	5	standard	standard	ADJ
aji-171	238	6	information	information	NOUN
aji-171	238	7	about	about	ADP
aji-171	238	8	the	the	DET
aji-171	238	9	clinical	clinical	ADJ
aji-171	238	10	validation	validation	NOUN
aji-171	238	11	and	and	CCONJ
aji-171	238	12	application	application	NOUN
aji-171	238	13	of	of	ADP
aji-171	238	14	biomarkers	biomarker	NOUN
aji-171	238	15	would	would	AUX
aji-171	238	16	also	also	ADV
aji-171	238	17	be	be	AUX
aji-171	238	18	pertinent	pertinent	ADJ
aji-171	238	19	to	to	ADP
aji-171	238	20	the	the	DET
aji-171	238	21	research	research	NOUN
aji-171	238	22	on	on	ADP
aji-171	238	23	them	they	PRON
aji-171	238	24	.	.	PUNCT
aji-171	239	1	furthermore	furthermore	ADV
aji-171	239	2	,	,	PUNCT
aji-171	239	3	miller	miller	PROPN
aji-171	239	4	et	et	PROPN
aji-171	239	5	al	al	PROPN
aji-171	239	6	.	.	PROPN
aji-171	239	7	highlight	highlight	VERB
aji-171	239	8	the	the	DET
aji-171	239	9	importance	importance	NOUN
aji-171	239	10	of	of	ADP
aji-171	239	11	idh	idh	NOUN
aji-171	239	12	mutations	mutation	NOUN
aji-171	239	13	and	and	CCONJ
aji-171	239	14	their	their	PRON
aji-171	239	15	metabolite	metabolite	NOUN
aji-171	239	16	,	,	PUNCT
aji-171	239	17	2	2	NUM
aji-171	239	18	-	-	PUNCT
aji-171	239	19	hg	hg	NOUN
aji-171	239	20	,	,	PUNCT
aji-171	239	21	in	in	ADP
aji-171	239	22	the	the	DET
aji-171	239	23	diagnosis	diagnosis	NOUN
aji-171	239	24	and	and	CCONJ
aji-171	239	25	management	management	NOUN
aji-171	239	26	of	of	ADP
aji-171	239	27	gliomas	glioma	NOUN
aji-171	239	28	(	(	PUNCT
aji-171	239	29	miller	miller	PROPN
aji-171	239	30	et	et	PROPN
aji-171	239	31	al	al	PROPN
aji-171	239	32	.	.	PROPN
aji-171	239	33	,	,	PUNCT
aji-171	239	34	2023	2023	NUM
aji-171	239	35	)	)	PUNCT
aji-171	239	36	.	.	PUNCT
aji-171	240	1	a	a	DET
aji-171	240	2	reliable	reliable	ADJ
aji-171	240	3	biomarker	biomarker	NOUN
aji-171	240	4	for	for	ADP
aji-171	240	5	idh	idh	NOUN
aji-171	240	6	-	-	PUNCT
aji-171	240	7	mutant	mutant	NOUN
aji-171	240	8	gliomas	glioma	NOUN
aji-171	240	9	,	,	PUNCT
aji-171	240	10	elevated	elevate	VERB
aji-171	240	11	2	2	NUM
aji-171	240	12	-	-	PUNCT
aji-171	240	13	hg	hg	NOUN
aji-171	240	14	levels	level	NOUN
aji-171	240	15	can	can	AUX
aji-171	240	16	be	be	AUX
aji-171	240	17	found	find	VERB
aji-171	240	18	using	use	VERB
aji-171	240	19	non	non	ADJ
aji-171	240	20	-	-	ADJ
aji-171	240	21	invasive	invasive	ADJ
aji-171	240	22	techniques	technique	NOUN
aji-171	240	23	.	.	PUNCT
aji-171	241	1	clinically	clinically	ADV
aji-171	241	2	speaking	speak	VERB
aji-171	241	3	,	,	PUNCT
aji-171	241	4	idh	idh	NOUN
aji-171	241	5	mutations	mutation	NOUN
aji-171	241	6	differ	differ	VERB
aji-171	241	7	from	from	ADP
aji-171	241	8	gliomas	glioma	NOUN
aji-171	241	9	with	with	ADP
aji-171	241	10	wild	wild	ADJ
aji-171	241	11	-	-	PUNCT
aji-171	241	12	type	type	NOUN
aji-171	241	13	idh	idh	NOUN
aji-171	241	14	in	in	ADP
aji-171	241	15	that	that	SCONJ
aji-171	241	16	they	they	PRON
aji-171	241	17	offer	offer	VERB
aji-171	241	18	higher	high	ADJ
aji-171	241	19	survival	survival	NOUN
aji-171	241	20	rates	rate	NOUN
aji-171	241	21	than	than	SCONJ
aji-171	241	22	are	be	AUX
aji-171	241	23	otherwise	otherwise	ADV
aji-171	241	24	observed	observe	VERB
aji-171	241	25	.	.	PUNCT
aji-171	242	1	targeted	target	VERB
aji-171	242	2	treatments	treatment	NOUN
aji-171	242	3	for	for	ADP
aji-171	242	4	these	these	DET
aji-171	242	5	mutations	mutation	NOUN
aji-171	242	6	also	also	ADV
aji-171	242	7	have	have	VERB
aji-171	242	8	the	the	DET
aji-171	242	9	potential	potential	NOUN
aji-171	242	10	to	to	PART
aji-171	242	11	alter	alter	VERB
aji-171	242	12	the	the	DET
aji-171	242	13	tumor	tumor	NOUN
aji-171	242	14	ecosystem	ecosystem	NOUN
aji-171	242	15	in	in	ADP
aji-171	242	16	order	order	NOUN
aji-171	242	17	to	to	PART
aji-171	242	18	enhance	enhance	VERB
aji-171	242	19	therapeutics	therapeutic	NOUN
aji-171	242	20	.	.	PUNCT
aji-171	243	1	these	these	DET
aji-171	243	2	findings	finding	NOUN
aji-171	243	3	demonstrate	demonstrate	VERB
aji-171	243	4	how	how	SCONJ
aji-171	243	5	crucial	crucial	ADJ
aji-171	243	6	idh	idh	NOUN
aji-171	243	7	mutations	mutation	NOUN
aji-171	243	8	are	be	AUX
aji-171	243	9	to	to	ADP
aji-171	243	10	improving	improve	VERB
aji-171	243	11	glioma	glioma	ADJ
aji-171	243	12	diagnosis	diagnosis	NOUN
aji-171	243	13	and	and	CCONJ
aji-171	243	14	treatment	treatment	NOUN
aji-171	243	15	accuracy	accuracy	NOUN
aji-171	243	16	.	.	PUNCT
aji-171	244	1	according	accord	VERB
aji-171	244	2	to	to	ADP
aji-171	244	3	dallas	dallas	PROPN
aji-171	244	4	pozza	pozza	PROPN
aji-171	244	5	et	et	PROPN
aji-171	244	6	al	al	PROPN
aji-171	244	7	.	.	PROPN
aji-171	245	1	(	(	PUNCT
aji-171	245	2	2020	2020	NUM
aji-171	245	3	)	)	PUNCT
aji-171	245	4	,	,	PUNCT
aji-171	245	5	succinate	succinate	NOUN
aji-171	245	6	is	be	AUX
aji-171	245	7	another	another	DET
aji-171	245	8	significant	significant	ADJ
aji-171	245	9	biomarker	biomarker	NOUN
aji-171	245	10	that	that	PRON
aji-171	245	11	builds	build	VERB
aji-171	245	12	up	up	ADP
aji-171	245	13	in	in	ADP
aji-171	245	14	some	some	DET
aji-171	245	15	forms	form	NOUN
aji-171	245	16	of	of	ADP
aji-171	245	17	paragangliomas	paraganglioma	NOUN
aji-171	245	18	and	and	CCONJ
aji-171	245	19	pheochromocytomas	pheochromocytoma	NOUN
aji-171	245	20	as	as	ADP
aji-171	245	21	a	a	DET
aji-171	245	22	result	result	NOUN
aji-171	245	23	of	of	ADP
aji-171	245	24	mutations	mutation	NOUN
aji-171	245	25	in	in	ADP
aji-171	245	26	the	the	DET
aji-171	245	27	enzyme	enzyme	NOUN
aji-171	245	28	succinate	succinate	NOUN
aji-171	245	29	dehydrogenase	dehydrogenase	NOUN
aji-171	245	30	(	(	PUNCT
aji-171	245	31	sdh	sdh	PROPN
aji-171	245	32	)	)	PUNCT
aji-171	245	33	.	.	PUNCT
aji-171	246	1	similarly	similarly	ADV
aji-171	246	2	,	,	PUNCT
aji-171	246	3	hereditary	hereditary	ADJ
aji-171	246	4	leiomyomatosis	leiomyomatosis	NOUN
aji-171	246	5	and	and	CCONJ
aji-171	246	6	renal	renal	ADJ
aji-171	246	7	cell	cell	NOUN
aji-171	246	8	carcinoma	carcinoma	NOUN
aji-171	246	9	cause	cause	VERB
aji-171	246	10	fumarate	fumarate	NOUN
aji-171	246	11	to	to	PART
aji-171	246	12	build	build	VERB
aji-171	246	13	up	up	ADP
aji-171	246	14	as	as	ADP
aji-171	246	15	a	a	DET
aji-171	246	16	result	result	NOUN
aji-171	246	17	of	of	ADP
aji-171	246	18	mutations	mutation	NOUN
aji-171	246	19	in	in	ADP
aji-171	246	20	fumarate	fumarate	ADJ
aji-171	246	21	hydratase	hydratase	NOUN
aji-171	246	22	(	(	PUNCT
aji-171	246	23	fh	fh	PROPN
aji-171	246	24	)	)	PUNCT
aji-171	246	25	(	(	PUNCT
aji-171	246	26	trpkov	trpkov	NOUN
aji-171	246	27	et	et	NOUN
aji-171	246	28	al	al	PROPN
aji-171	246	29	.	.	PROPN
aji-171	246	30	,	,	PUNCT
aji-171	246	31	2016	2016	NUM
aji-171	246	32	;	;	PUNCT
aji-171	246	33	wang	wang	PROPN
aji-171	246	34	et	et	PROPN
aji-171	246	35	al	al	PROPN
aji-171	246	36	.	.	PROPN
aji-171	246	37	,	,	PUNCT
aji-171	246	38	2024	2024	NUM
aji-171	246	39	)	)	PUNCT
aji-171	246	40	.	.	PUNCT
aji-171	247	1	thus	thus	ADV
aji-171	247	2	,	,	PUNCT
aji-171	247	3	these	these	DET
aji-171	247	4	metabolites	metabolite	NOUN
aji-171	247	5	play	play	VERB
aji-171	247	6	a	a	DET
aji-171	247	7	role	role	NOUN
aji-171	247	8	in	in	ADP
aji-171	247	9	identifying	identify	VERB
aji-171	247	10	hereditary	hereditary	ADJ
aji-171	247	11	cancer	cancer	NOUN
aji-171	247	12	syndromes	syndrome	NOUN
aji-171	247	13	and	and	CCONJ
aji-171	247	14	assessing	assess	VERB
aji-171	247	15	cancer	cancer	NOUN
aji-171	247	16	risks	risk	NOUN
aji-171	247	17	(	(	PUNCT
aji-171	247	18	collins	collins	PROPN
aji-171	247	19	et	et	PROPN
aji-171	247	20	al	al	PROPN
aji-171	247	21	.	.	PROPN
aji-171	247	22	,	,	PUNCT
aji-171	247	23	2017	2017	NUM
aji-171	247	24	;	;	PUNCT
aji-171	247	25	di	di	PROPN
aji-171	247	26	gregorio	gregorio	PROPN
aji-171	247	27	et	et	PROPN
aji-171	247	28	al	al	PROPN
aji-171	247	29	.	.	PROPN
aji-171	247	30	,	,	PUNCT
aji-171	247	31	2021	2021	NUM
aji-171	247	32	)	)	PUNCT
aji-171	247	33	by	by	ADP
aji-171	247	34	acting	act	VERB
aji-171	247	35	as	as	ADP
aji-171	247	36	"	"	PUNCT
aji-171	247	37	oncometabolites	oncometabolite	NOUN
aji-171	247	38	"	"	PUNCT
aji-171	247	39	that	that	PRON
aji-171	247	40	drive	drive	VERB
aji-171	247	41	dna	dna	PROPN
aji-171	247	42	methylation	methylation	NOUN
aji-171	247	43	(	(	PUNCT
aji-171	247	44	lanzetti	lanzetti	ADJ
aji-171	247	45	,	,	PUNCT
aji-171	247	46	2024	2024	NUM
aji-171	247	47	)	)	PUNCT
aji-171	247	48	and	and	CCONJ
aji-171	247	49	hypoxia	hypoxia	NOUN
aji-171	247	50	-	-	PUNCT
aji-171	247	51	like	like	ADJ
aji-171	247	52	responses	response	NOUN
aji-171	247	53	(	(	PUNCT
aji-171	247	54	fandrey	fandrey	PROPN
aji-171	247	55	et	et	PROPN
aji-171	247	56	al	al	PROPN
aji-171	247	57	.	.	PROPN
aji-171	247	58	,	,	PUNCT
aji-171	247	59	2019	2019	NUM
aji-171	247	60	)	)	PUNCT
aji-171	247	61	.	.	PUNCT
aji-171	248	1	according	accord	VERB
aji-171	248	2	to	to	ADP
aji-171	248	3	vo	vo	PROPN
aji-171	248	4	and	and	CCONJ
aji-171	248	5	trinh	trinh	PROPN
aji-171	248	6	(	(	PUNCT
aji-171	248	7	2024	2024	NUM
aji-171	248	8	)	)	PUNCT
aji-171	248	9	,	,	PUNCT
aji-171	248	10	alterations	alteration	NOUN
aji-171	248	11	in	in	ADP
aji-171	248	12	lipid	lipid	ADJ
aji-171	248	13	metabolism	metabolism	NOUN
aji-171	248	14	metabolites	metabolite	NOUN
aji-171	248	15	,	,	PUNCT
aji-171	248	16	such	such	ADJ
aji-171	248	17	as	as	ADP
aji-171	248	18	phosphocholine	phosphocholine	NOUN
aji-171	248	19	,	,	PUNCT
aji-171	248	20	are	be	AUX
aji-171	248	21	also	also	ADV
aji-171	248	22	being	be	AUX
aji-171	248	23	found	find	VERB
aji-171	248	24	to	to	PART
aji-171	248	25	be	be	AUX
aji-171	248	26	biomarkers	biomarker	NOUN
aji-171	248	27	for	for	ADP
aji-171	248	28	prostate	prostate	NOUN
aji-171	248	29	and	and	CCONJ
aji-171	248	30	breast	breast	NOUN
aji-171	248	31	cancers	cancer	NOUN
aji-171	248	32	.	.	PUNCT
aji-171	249	1	tumor	tumor	NOUN
aji-171	249	2	growth	growth	NOUN
aji-171	249	3	is	be	AUX
aji-171	249	4	indicated	indicate	VERB
aji-171	249	5	by	by	ADP
aji-171	249	6	elevated	elevated	ADJ
aji-171	249	7	levels	level	NOUN
aji-171	249	8	of	of	ADP
aji-171	249	9	phosphocholine	phosphocholine	NOUN
aji-171	249	10	and	and	CCONJ
aji-171	249	11	other	other	ADJ
aji-171	249	12	lipid	lipid	NOUN
aji-171	249	13	-	-	PUNCT
aji-171	249	14	related	relate	VERB
aji-171	249	15	metabolites	metabolite	NOUN
aji-171	249	16	,	,	PUNCT
aji-171	249	17	which	which	PRON
aji-171	249	18	can	can	AUX
aji-171	249	19	also	also	ADV
aji-171	249	20	provide	provide	VERB
aji-171	249	21	diagnostic	diagnostic	ADJ
aji-171	249	22	details	detail	NOUN
aji-171	249	23	about	about	ADP
aji-171	249	24	different	different	ADJ
aji-171	249	25	cancer	cancer	NOUN
aji-171	249	26	subtypes	subtype	NOUN
aji-171	249	27	.	.	PUNCT
aji-171	250	1	in	in	ADP
aji-171	250	2	addition	addition	NOUN
aji-171	250	3	to	to	ADP
aji-171	250	4	supporting	support	VERB
aji-171	250	5	early	early	ADJ
aji-171	250	6	diagnosis	diagnosis	NOUN
aji-171	250	7	,	,	PUNCT
aji-171	250	8	these	these	DET
aji-171	250	9	important	important	ADJ
aji-171	250	10	biomarkers	biomarker	NOUN
aji-171	250	11	also	also	ADV
aji-171	250	12	offer	offer	VERB
aji-171	250	13	valuable	valuable	ADJ
aji-171	250	14	insights	insight	NOUN
aji-171	250	15	into	into	ADP
aji-171	250	16	tumor	tumor	NOUN
aji-171	250	17	behavior	behavior	NOUN
aji-171	250	18	and	and	CCONJ
aji-171	250	19	enable	enable	VERB
aji-171	250	20	personalized	personalized	ADJ
aji-171	250	21	prognosis	prognosis	NOUN
aji-171	250	22	,	,	PUNCT
aji-171	250	23	which	which	PRON
aji-171	250	24	leads	lead	VERB
aji-171	250	25	to	to	ADP
aji-171	250	26	targeted	target	VERB
aji-171	250	27	therapies	therapy	NOUN
aji-171	250	28	.	.	PUNCT
aji-171	251	1	as	as	SCONJ
aji-171	251	2	science	science	NOUN
aji-171	251	3	continues	continue	VERB
aji-171	251	4	to	to	PART
aji-171	251	5	advance	advance	VERB
aji-171	251	6	,	,	PUNCT
aji-171	251	7	the	the	DET
aji-171	251	8	identification	identification	NOUN
aji-171	251	9	of	of	ADP
aji-171	251	10	biomarkers	biomarker	NOUN
aji-171	251	11	and	and	CCONJ
aji-171	251	12	their	their	PRON
aji-171	251	13	clinical	clinical	ADJ
aji-171	251	14	applications	application	NOUN
aji-171	251	15	continue	continue	VERB
aji-171	251	16	to	to	PART
aji-171	251	17	grow	grow	VERB
aji-171	251	18	.	.	PUNCT
aji-171	252	1	according	accord	VERB
aji-171	252	2	to	to	ADP
aji-171	252	3	vo	vo	PROPN
aji-171	252	4	and	and	CCONJ
aji-171	252	5	trinh	trinh	PROPN
aji-171	252	6	(	(	PUNCT
aji-171	252	7	2024	2024	NUM
aji-171	252	8	)	)	PUNCT
aji-171	252	9	,	,	PUNCT
aji-171	252	10	these	these	PRON
aji-171	252	11	enhance	enhance	NOUN
aji-171	252	12	precision	precision	NOUN
aji-171	252	13	oncology	oncology	NOUN
aji-171	252	14	and	and	CCONJ
aji-171	252	15	enable	enable	VERB
aji-171	252	16	therapies	therapy	NOUN
aji-171	252	17	that	that	PRON
aji-171	252	18	are	be	AUX
aji-171	252	19	truly	truly	ADV
aji-171	252	20	customized	customize	VERB
aji-171	252	21	to	to	ADP
aji-171	252	22	a	a	DET
aji-171	252	23	patient	patient	NOUN
aji-171	252	24	's	's	PART
aji-171	252	25	metabolic	metabolic	NOUN
aji-171	252	26	profile	profile	NOUN
aji-171	252	27	.	.	PUNCT
aji-171	253	1	4	4	X
aji-171	253	2	.	.	X
aji-171	253	3	biomarkers	biomarker	NOUN
aji-171	253	4	for	for	ADP
aji-171	253	5	mental	mental	ADJ
aji-171	253	6	health	health	NOUN
aji-171	253	7	and	and	CCONJ
aji-171	253	8	neurodegenerative	neurodegenerative	ADJ
aji-171	253	9	disease	disease	NOUN
aji-171	253	10	4.1	4.1	NUM
aji-171	253	11	neurodegenerative	neurodegenerative	ADJ
aji-171	253	12	diseases	disease	NOUN
aji-171	253	13	and	and	CCONJ
aji-171	253	14	metabolomics	metabolomic	NOUN
aji-171	253	15	a	a	DET
aji-171	253	16	powerful	powerful	ADJ
aji-171	253	17	tool	tool	NOUN
aji-171	253	18	in	in	ADP
aji-171	253	19	the	the	DET
aji-171	253	20	hunt	hunt	NOUN
aji-171	253	21	for	for	ADP
aji-171	253	22	neurodegenerative	neurodegenerative	ADJ
aji-171	253	23	diseases	disease	NOUN
aji-171	253	24	is	be	AUX
aji-171	253	25	metabolomics	metabolomic	NOUN
aji-171	253	26	,	,	PUNCT
aji-171	253	27	which	which	PRON
aji-171	253	28	makes	make	VERB
aji-171	253	29	it	it	PRON
aji-171	253	30	possible	possible	ADJ
aji-171	253	31	to	to	PART
aji-171	253	32	identify	identify	VERB
aji-171	253	33	biomarkers	biomarker	NOUN
aji-171	253	34	connected	connect	VERB
aji-171	253	35	to	to	ADP
aji-171	253	36	the	the	DET
aji-171	253	37	course	course	NOUN
aji-171	253	38	of	of	ADP
aji-171	253	39	the	the	DET
aji-171	253	40	illness	illness	NOUN
aji-171	253	41	and	and	CCONJ
aji-171	253	42	use	use	VERB
aji-171	253	43	them	they	PRON
aji-171	253	44	for	for	ADP
aji-171	253	45	diagnosis	diagnosis	NOUN
aji-171	253	46	and	and	CCONJ
aji-171	253	47	treatment	treatment	NOUN
aji-171	253	48	monitoring	monitoring	NOUN
aji-171	253	49	.	.	PUNCT
aji-171	254	1	in	in	ADP
aji-171	254	2	the	the	DET
aji-171	254	3	early	early	ADJ
aji-171	254	4	stages	stage	NOUN
aji-171	254	5	of	of	ADP
aji-171	254	6	detection	detection	NOUN
aji-171	254	7	and	and	CCONJ
aji-171	254	8	differential	differential	ADJ
aji-171	254	9	diagnosis	diagnosis	NOUN
aji-171	254	10	,	,	PUNCT
aji-171	254	11	diseases	disease	NOUN
aji-171	254	12	like	like	ADP
aji-171	254	13	alzheimer	alzheimer	PROPN
aji-171	254	14	's	's	PART
aji-171	254	15	disease	disease	NOUN
aji-171	254	16	(	(	PUNCT
aji-171	254	17	ad	ad	NOUN
aji-171	254	18	)	)	PUNCT
aji-171	254	19	,	,	PUNCT
aji-171	254	20	parkinson	parkinson	NOUN
aji-171	254	21	's	's	PART
aji-171	254	22	disease	disease	NOUN
aji-171	254	23	(	(	PUNCT
aji-171	254	24	pd	pd	NOUN
aji-171	254	25	)	)	PUNCT
aji-171	254	26	,	,	PUNCT
aji-171	254	27	and	and	CCONJ
aji-171	254	28	amyotrophic	amyotrophic	ADJ
aji-171	254	29	lateral	lateral	ADJ
aji-171	254	30	sclerosis	sclerosis	NOUN
aji-171	254	31	(	(	PUNCT
aji-171	254	32	als	als	NOUN
aji-171	254	33	)	)	PUNCT
aji-171	254	34	are	be	AUX
aji-171	254	35	useful	useful	ADJ
aji-171	254	36	because	because	SCONJ
aji-171	254	37	they	they	PRON
aji-171	254	38	exhibit	exhibit	VERB
aji-171	254	39	specific	specific	ADJ
aji-171	254	40	metabolic	metabolic	NOUN
aji-171	254	41	alterations	alteration	NOUN
aji-171	254	42	linked	link	VERB
aji-171	254	43	to	to	ADP
aji-171	254	44	the	the	DET
aji-171	254	45	underlying	underlying	ADJ
aji-171	254	46	pathophysiological	pathophysiological	ADJ
aji-171	254	47	mechanisms	mechanism	NOUN
aji-171	254	48	in	in	ADP
aji-171	254	49	these	these	DET
aji-171	254	50	conditions	condition	NOUN
aji-171	254	51	(	(	PUNCT
aji-171	254	52	dubois	dubois	PROPN
aji-171	254	53	et	et	PROPN
aji-171	254	54	al	al	PROPN
aji-171	254	55	.	.	PROPN
aji-171	254	56	,	,	PUNCT
aji-171	254	57	2023	2023	NUM
aji-171	254	58	)	)	PUNCT
aji-171	254	59	.	.	PUNCT
aji-171	255	1	glutamate	glutamate	VERB
aji-171	255	2	,	,	PUNCT
aji-171	255	3	myoinositol	myoinositol	ADJ
aji-171	255	4	,	,	PUNCT
aji-171	255	5	and	and	CCONJ
aji-171	255	6	phosphatidylcholine	phosphatidylcholine	NOUN
aji-171	255	7	are	be	AUX
aji-171	255	8	biomarkers	biomarker	NOUN
aji-171	255	9	of	of	ADP
aji-171	255	10	alzheimer	alzheimer	PROPN
aji-171	255	11	's	's	PART
aji-171	255	12	disease	disease	NOUN
aji-171	255	13	that	that	PRON
aji-171	255	14	are	be	AUX
aji-171	255	15	associated	associate	VERB
aji-171	255	16	with	with	ADP
aji-171	255	17	inflammation	inflammation	NOUN
aji-171	255	18	,	,	PUNCT
aji-171	255	19	oxidative	oxidative	ADJ
aji-171	255	20	stress	stress	NOUN
aji-171	255	21	,	,	PUNCT
aji-171	255	22	and	and	CCONJ
aji-171	255	23	neuronal	neuronal	ADJ
aji-171	255	24	damage	damage	NOUN
aji-171	255	25	(	(	PUNCT
aji-171	255	26	zhang	zhang	X
aji-171	255	27	et	et	PROPN
aji-171	255	28	al	al	PROPN
aji-171	255	29	.	.	PROPN
aji-171	255	30	,	,	PUNCT
aji-171	255	31	2023	2023	NUM
aji-171	255	32	;	;	PUNCT
aji-171	255	33	reveglia	reveglia	PROPN
aji-171	255	34	et	et	PROPN
aji-171	255	35	al	al	PROPN
aji-171	255	36	.	.	PROPN
aji-171	255	37	,	,	PUNCT
aji-171	255	38	2023	2023	NUM
aji-171	255	39	;	;	PUNCT
aji-171	255	40	wang	wang	PROPN
aji-171	255	41	et	et	PROPN
aji-171	255	42	al	al	PROPN
aji-171	255	43	.	.	PROPN
aji-171	255	44	,	,	PUNCT
aji-171	255	45	2024	2024	NUM
aji-171	255	46	)	)	PUNCT
aji-171	255	47	.	.	PUNCT
aji-171	256	1	low	low	ADJ
aji-171	256	2	levels	level	NOUN
aji-171	256	3	of	of	ADP
aji-171	256	4	acetyl	acetyl	NOUN
aji-171	256	5	-	-	PUNCT
aji-171	256	6	lcarnitine	lcarnitine	NOUN
aji-171	256	7	are	be	AUX
aji-171	256	8	linked	link	VERB
aji-171	256	9	to	to	ADP
aji-171	256	10	mitochondrial	mitochondrial	ADJ
aji-171	256	11	dysfunction	dysfunction	NOUN
aji-171	256	12	and	and	CCONJ
aji-171	256	13	cognitive	cognitive	ADJ
aji-171	256	14	decline	decline	NOUN
aji-171	256	15	(	(	PUNCT
aji-171	256	16	pennisi	pennisi	VERB
aji-171	256	17	et	et	PROPN
aji-171	256	18	al	al	PROPN
aji-171	256	19	.	.	PROPN
aji-171	256	20	,	,	PUNCT
aji-171	256	21	2020	2020	NUM
aji-171	256	22	)	)	PUNCT
aji-171	256	23	,	,	PUNCT
aji-171	256	24	while	while	SCONJ
aji-171	256	25	elevated	elevated	ADJ
aji-171	256	26	myoinositol	myoinositol	NOUN
aji-171	256	27	levels	level	NOUN
aji-171	256	28	have	have	AUX
aji-171	256	29	been	be	AUX
aji-171	256	30	linked	link	VERB
aji-171	256	31	to	to	AUX
aji-171	256	32	amyloid	amyloid	VERB
aji-171	256	33	plaque	plaque	NOUN
aji-171	256	34	deposition	deposition	NOUN
aji-171	256	35	,	,	PUNCT
aji-171	256	36	one	one	NUM
aji-171	256	37	of	of	ADP
aji-171	256	38	the	the	DET
aji-171	256	39	hallmark	hallmark	ADJ
aji-171	256	40	events	event	NOUN
aji-171	256	41	of	of	ADP
aji-171	256	42	ad	ad	NOUN
aji-171	256	43	(	(	PUNCT
aji-171	256	44	voevodskaya	voevodskaya	NOUN
aji-171	256	45	et	et	PROPN
aji-171	256	46	al	al	PROPN
aji-171	256	47	.	.	PROPN
aji-171	256	48	,	,	PUNCT
aji-171	256	49	2016	2016	NUM
aji-171	256	50	)	)	PUNCT
aji-171	256	51	.	.	PUNCT
aji-171	257	1	early	early	ADJ
aji-171	257	2	intervention	intervention	NOUN
aji-171	257	3	may	may	AUX
aji-171	257	4	be	be	AUX
aji-171	257	5	possible	possible	ADJ
aji-171	257	6	because	because	SCONJ
aji-171	257	7	other	other	ADJ
aji-171	257	8	lipidrelated	lipidrelated	ADJ
aji-171	257	9	metabolites	metabolite	NOUN
aji-171	257	10	,	,	PUNCT
aji-171	257	11	which	which	PRON
aji-171	257	12	involve	involve	VERB
aji-171	257	13	specific	specific	ADJ
aji-171	257	14	phospholipids	phospholipid	NOUN
aji-171	257	15	,	,	PUNCT
aji-171	257	16	are	be	AUX
aji-171	257	17	being	be	AUX
aji-171	257	18	investigated	investigate	VERB
aji-171	257	19	as	as	ADP
aji-171	257	20	biomarkers	biomarker	NOUN
aji-171	257	21	of	of	ADP
aji-171	257	22	the	the	DET
aji-171	257	23	preclinical	preclinical	ADJ
aji-171	257	24	stages	stage	NOUN
aji-171	257	25	of	of	ADP
aji-171	257	26	ad	ad	NOUN
aji-171	257	27	.	.	PUNCT
aji-171	258	1	dopamine	dopamine	NOUN
aji-171	258	2	,	,	PUNCT
aji-171	258	3	uric	uric	ADJ
aji-171	258	4	acid	acid	NOUN
aji-171	258	5	,	,	PUNCT
aji-171	258	6	and	and	CCONJ
aji-171	258	7	homovanillic	homovanillic	PROPN
aji-171	258	8	acid	acid	PROPN
aji-171	258	9	are	be	AUX
aji-171	258	10	the	the	DET
aji-171	258	11	main	main	ADJ
aji-171	258	12	metabolomics	metabolomic	NOUN
aji-171	258	13	biomarkers	biomarker	NOUN
aji-171	258	14	that	that	PRON
aji-171	258	15	have	have	AUX
aji-171	258	16	been	be	AUX
aji-171	258	17	investigated	investigate	VERB
aji-171	258	18	in	in	ADP
aji-171	258	19	the	the	DET
aji-171	258	20	context	context	NOUN
aji-171	258	21	of	of	ADP
aji-171	258	22	parkinson	parkinson	NOUN
aji-171	258	23	's	's	PART
aji-171	258	24	disease	disease	NOUN
aji-171	258	25	(	(	PUNCT
aji-171	258	26	kremer	kremer	PROPN
aji-171	258	27	et	et	PROPN
aji-171	258	28	al	al	PROPN
aji-171	258	29	.	.	PROPN
aji-171	258	30	,	,	PUNCT
aji-171	258	31	2021	2021	NUM
aji-171	258	32	)	)	PUNCT
aji-171	258	33	.	.	PUNCT
aji-171	259	1	dopamine	dopamine	NOUN
aji-171	259	2	depletion	depletion	NOUN
aji-171	259	3	brought	bring	VERB
aji-171	259	4	on	on	ADP
aji-171	259	5	by	by	ADP
aji-171	259	6	dopaminergic	dopaminergic	ADJ
aji-171	259	7	neuron	neuron	NOUN
aji-171	259	8	mamman	mamman	PROPN
aji-171	259	9	et	et	PROPN
aji-171	259	10	al	al	PROPN
aji-171	259	11	.	.	PROPN
aji-171	259	12	;	;	PUNCT
aji-171	259	13	asian	asian	PROPN
aji-171	259	14	j.	j.	PROPN
aji-171	259	15	immunol	immunol	PROPN
aji-171	259	16	.	.	PROPN
aji-171	259	17	,	,	PUNCT
aji-171	259	18	vol	vol	NOUN
aji-171	259	19	.	.	PROPN
aji-171	259	20	8	8	NUM
aji-171	259	21	,	,	PUNCT
aji-171	259	22	no	no	INTJ
aji-171	259	23	.	.	NOUN
aji-171	259	24	1	1	NUM
aji-171	259	25	,	,	PUNCT
aji-171	259	26	pp	pp	ADJ
aji-171	259	27	.	.	PUNCT
aji-171	260	1	190	190	NUM
aji-171	260	2	-	-	SYM
aji-171	260	3	206	206	NUM
aji-171	260	4	,	,	PUNCT
aji-171	260	5	2025	2025	NUM
aji-171	260	6	;	;	PUNCT
aji-171	260	7	article	article	NOUN
aji-171	260	8	no.aji.140476	no.aji.140476	PART
aji-171	260	9	197	197	NUM
aji-171	260	10	degeneration	degeneration	NOUN
aji-171	260	11	is	be	AUX
aji-171	260	12	a	a	DET
aji-171	260	13	key	key	ADJ
aji-171	260	14	component	component	NOUN
aji-171	260	15	of	of	ADP
aji-171	260	16	parkinson	parkinson	NOUN
aji-171	260	17	's	's	PART
aji-171	260	18	disease	disease	NOUN
aji-171	260	19	.	.	PUNCT
aji-171	261	1	conversely	conversely	ADV
aji-171	261	2	,	,	PUNCT
aji-171	261	3	there	there	PRON
aji-171	261	4	is	be	VERB
aji-171	261	5	an	an	DET
aji-171	261	6	increase	increase	NOUN
aji-171	261	7	in	in	ADP
aji-171	261	8	homovanillic	homovanillic	NOUN
aji-171	261	9	acid	acid	NOUN
aji-171	261	10	,	,	PUNCT
aji-171	261	11	a	a	DET
aji-171	261	12	dopamine	dopamine	NOUN
aji-171	261	13	metabolite	metabolite	NOUN
aji-171	261	14	that	that	PRON
aji-171	261	15	could	could	AUX
aji-171	261	16	indicate	indicate	VERB
aji-171	261	17	the	the	DET
aji-171	261	18	severity	severity	NOUN
aji-171	261	19	of	of	ADP
aji-171	261	20	the	the	DET
aji-171	261	21	illness	illness	NOUN
aji-171	261	22	(	(	PUNCT
aji-171	261	23	kremer	kremer	PROPN
aji-171	261	24	et	et	PROPN
aji-171	261	25	al	al	PROPN
aji-171	261	26	.	.	PROPN
aji-171	261	27	,	,	PUNCT
aji-171	261	28	2021	2021	NUM
aji-171	261	29	)	)	PUNCT
aji-171	261	30	.	.	PUNCT
aji-171	262	1	oxidative	oxidative	ADJ
aji-171	262	2	stress	stress	NOUN
aji-171	262	3	has	have	AUX
aji-171	262	4	been	be	AUX
aji-171	262	5	implicated	implicate	VERB
aji-171	262	6	in	in	ADP
aji-171	262	7	a	a	DET
aji-171	262	8	higher	high	ADJ
aji-171	262	9	risk	risk	NOUN
aji-171	262	10	of	of	ADP
aji-171	262	11	parkinson	parkinson	NOUN
aji-171	262	12	's	's	PART
aji-171	262	13	disease	disease	NOUN
aji-171	262	14	(	(	PUNCT
aji-171	262	15	pd	pd	NOUN
aji-171	262	16	)	)	PUNCT
aji-171	262	17	,	,	PUNCT
aji-171	262	18	as	as	SCONJ
aji-171	262	19	evidenced	evidence	VERB
aji-171	262	20	by	by	ADP
aji-171	262	21	lower	low	ADJ
aji-171	262	22	levels	level	NOUN
aji-171	262	23	of	of	ADP
aji-171	262	24	the	the	DET
aji-171	262	25	antioxidant	antioxidant	ADJ
aji-171	262	26	uric	uric	ADJ
aji-171	262	27	acid	acid	NOUN
aji-171	262	28	(	(	PUNCT
aji-171	262	29	seifar	seifar	ADV
aji-171	262	30	et	et	PROPN
aji-171	262	31	al	al	PROPN
aji-171	262	32	.	.	PROPN
aji-171	262	33	,	,	PUNCT
aji-171	262	34	2022	2022	NUM
aji-171	262	35	)	)	PUNCT
aji-171	262	36	.	.	PUNCT
aji-171	263	1	in	in	ADP
aji-171	263	2	als	al	NOUN
aji-171	263	3	,	,	PUNCT
aji-171	263	4	biomarkers	biomarker	NOUN
aji-171	263	5	like	like	ADP
aji-171	263	6	creatine	creatine	NOUN
aji-171	263	7	,	,	PUNCT
aji-171	263	8	ascorbate	ascorbate	NOUN
aji-171	263	9	,	,	PUNCT
aji-171	263	10	and	and	CCONJ
aji-171	263	11	different	different	ADJ
aji-171	263	12	amino	amino	ADJ
aji-171	263	13	acids	acid	NOUN
aji-171	263	14	show	show	NOUN
aji-171	263	15	abnormalities	abnormality	NOUN
aji-171	263	16	in	in	ADP
aji-171	263	17	energy	energy	NOUN
aji-171	263	18	metabolism	metabolism	NOUN
aji-171	263	19	,	,	PUNCT
aji-171	263	20	neuroinflammation	neuroinflammation	NOUN
aji-171	263	21	,	,	PUNCT
aji-171	263	22	and	and	CCONJ
aji-171	263	23	oxidative	oxidative	ADJ
aji-171	263	24	stress	stress	NOUN
aji-171	263	25	(	(	PUNCT
aji-171	263	26	kori	kori	PROPN
aji-171	263	27	et	et	PROPN
aji-171	263	28	al	al	PROPN
aji-171	263	29	.	.	PROPN
aji-171	263	30	,	,	PUNCT
aji-171	263	31	2016	2016	NUM
aji-171	263	32	;	;	PUNCT
aji-171	263	33	lanznaster	lanznaster	NOUN
aji-171	263	34	et	et	PROPN
aji-171	263	35	al	al	PROPN
aji-171	263	36	.	.	PROPN
aji-171	263	37	,	,	PUNCT
aji-171	263	38	2018	2018	NUM
aji-171	263	39	)	)	PUNCT
aji-171	263	40	.	.	PUNCT
aji-171	264	1	while	while	SCONJ
aji-171	264	2	branched	branch	VERB
aji-171	264	3	-	-	PUNCT
aji-171	264	4	chain	chain	NOUN
aji-171	264	5	amino	amino	NOUN
aji-171	264	6	acid	acid	NOUN
aji-171	264	7	changes	change	NOUN
aji-171	264	8	reflect	reflect	VERB
aji-171	264	9	disruptions	disruption	NOUN
aji-171	264	10	in	in	ADP
aji-171	264	11	the	the	DET
aji-171	264	12	muscle	muscle	NOUN
aji-171	264	13	metabolism	metabolism	NOUN
aji-171	264	14	of	of	ADP
aji-171	264	15	these	these	DET
aji-171	264	16	vital	vital	ADJ
aji-171	264	17	nutrients	nutrient	NOUN
aji-171	264	18	in	in	ADP
aji-171	264	19	als	als	NOUN
aji-171	264	20	patients	patient	NOUN
aji-171	264	21	,	,	PUNCT
aji-171	264	22	lower	low	ADJ
aji-171	264	23	creatine	creatine	PROPN
aji-171	264	24	levels	level	NOUN
aji-171	264	25	signify	signify	VERB
aji-171	264	26	deficiencies	deficiency	NOUN
aji-171	264	27	in	in	ADP
aji-171	264	28	cellular	cellular	ADJ
aji-171	264	29	energy	energy	NOUN
aji-171	264	30	(	(	PUNCT
aji-171	264	31	parvanovova	parvanovova	X
aji-171	264	32	et	et	PROPN
aji-171	264	33	al	al	PROPN
aji-171	264	34	.	.	PROPN
aji-171	264	35	,	,	PUNCT
aji-171	264	36	2024	2024	NUM
aji-171	264	37	)	)	PUNCT
aji-171	264	38	.	.	PUNCT
aji-171	265	1	profiling	profile	VERB
aji-171	265	2	these	these	DET
aji-171	265	3	biomarkers	biomarker	NOUN
aji-171	265	4	using	use	VERB
aji-171	265	5	metabolomics	metabolomic	NOUN
aji-171	265	6	offers	offer	VERB
aji-171	265	7	a	a	DET
aji-171	265	8	better	well	ADJ
aji-171	265	9	understanding	understanding	NOUN
aji-171	265	10	of	of	ADP
aji-171	265	11	the	the	DET
aji-171	265	12	mechanisms	mechanism	NOUN
aji-171	265	13	underlying	underlie	VERB
aji-171	265	14	neurodegenerative	neurodegenerative	ADJ
aji-171	265	15	disease	disease	NOUN
aji-171	265	16	,	,	PUNCT
aji-171	265	17	which	which	PRON
aji-171	265	18	may	may	AUX
aji-171	265	19	lead	lead	VERB
aji-171	265	20	to	to	ADP
aji-171	265	21	early	early	ADJ
aji-171	265	22	diagnosis	diagnosis	NOUN
aji-171	265	23	and	and	CCONJ
aji-171	265	24	help	help	VERB
aji-171	265	25	distinguish	distinguish	VERB
aji-171	265	26	it	it	PRON
aji-171	265	27	from	from	ADP
aji-171	265	28	other	other	ADJ
aji-171	265	29	conditions	condition	NOUN
aji-171	265	30	.	.	PUNCT
aji-171	266	1	additionally	additionally	ADV
aji-171	266	2	,	,	PUNCT
aji-171	266	3	because	because	SCONJ
aji-171	266	4	metabolite	metabolite	NOUN
aji-171	266	5	levels	level	NOUN
aji-171	266	6	can	can	AUX
aji-171	266	7	be	be	AUX
aji-171	266	8	tracked	track	VERB
aji-171	266	9	to	to	PART
aji-171	266	10	evaluate	evaluate	VERB
aji-171	266	11	treatment	treatment	NOUN
aji-171	266	12	effectiveness	effectiveness	NOUN
aji-171	266	13	and	and	CCONJ
aji-171	266	14	select	select	VERB
aji-171	266	15	individualized	individualized	ADJ
aji-171	266	16	therapeutic	therapeutic	ADJ
aji-171	266	17	approaches	approach	NOUN
aji-171	266	18	in	in	ADP
aji-171	266	19	neurodegenerative	neurodegenerative	ADJ
aji-171	266	20	care	care	NOUN
aji-171	266	21	,	,	PUNCT
aji-171	266	22	these	these	DET
aji-171	266	23	biomarkers	biomarker	NOUN
aji-171	266	24	can	can	AUX
aji-171	266	25	provide	provide	VERB
aji-171	266	26	insights	insight	NOUN
aji-171	266	27	into	into	ADP
aji-171	266	28	the	the	DET
aji-171	266	29	development	development	NOUN
aji-171	266	30	of	of	ADP
aji-171	266	31	targeted	target	VERB
aji-171	266	32	therapies	therapy	NOUN
aji-171	266	33	(	(	PUNCT
aji-171	266	34	parvanovova	parvanovova	X
aji-171	266	35	et	et	PROPN
aji-171	266	36	al	al	PROPN
aji-171	266	37	.	.	PROPN
aji-171	266	38	,	,	PUNCT
aji-171	266	39	2024	2024	NUM
aji-171	266	40	)	)	PUNCT
aji-171	266	41	.	.	PUNCT
aji-171	267	1	4.2	4.2	NUM
aji-171	267	2	the	the	DET
aji-171	267	3	biomarkers	biomarker	NOUN
aji-171	267	4	of	of	ADP
aji-171	267	5	mental	mental	ADJ
aji-171	267	6	health	health	NOUN
aji-171	267	7	the	the	DET
aji-171	267	8	field	field	NOUN
aji-171	267	9	of	of	ADP
aji-171	267	10	mental	mental	ADJ
aji-171	267	11	health	health	NOUN
aji-171	267	12	research	research	NOUN
aji-171	267	13	has	have	AUX
aji-171	267	14	seen	see	VERB
aji-171	267	15	a	a	DET
aji-171	267	16	lot	lot	NOUN
aji-171	267	17	of	of	ADP
aji-171	267	18	use	use	NOUN
aji-171	267	19	of	of	ADP
aji-171	267	20	metabolomics	metabolomic	NOUN
aji-171	267	21	,	,	PUNCT
aji-171	267	22	particularly	particularly	ADV
aji-171	267	23	in	in	ADP
aji-171	267	24	the	the	DET
aji-171	267	25	hunt	hunt	NOUN
aji-171	267	26	for	for	ADP
aji-171	267	27	biomarkers	biomarker	NOUN
aji-171	267	28	linked	link	VERB
aji-171	267	29	to	to	ADP
aji-171	267	30	a	a	DET
aji-171	267	31	range	range	NOUN
aji-171	267	32	of	of	ADP
aji-171	267	33	psychiatric	psychiatric	ADJ
aji-171	267	34	conditions	condition	NOUN
aji-171	267	35	,	,	PUNCT
aji-171	267	36	such	such	ADJ
aji-171	267	37	as	as	ADP
aji-171	267	38	anxiety	anxiety	NOUN
aji-171	267	39	,	,	PUNCT
aji-171	267	40	bipolar	bipolar	ADJ
aji-171	267	41	disorder	disorder	NOUN
aji-171	267	42	,	,	PUNCT
aji-171	267	43	schizophrenia	schizophrenia	NOUN
aji-171	267	44	,	,	PUNCT
aji-171	267	45	and	and	CCONJ
aji-171	267	46	depression	depression	NOUN
aji-171	267	47	(	(	PUNCT
aji-171	267	48	abidargham	abidargham	PROPN
aji-171	267	49	et	et	PROPN
aji-171	267	50	al	al	PROPN
aji-171	267	51	.	.	PROPN
aji-171	267	52	,	,	PUNCT
aji-171	267	53	2023	2023	NUM
aji-171	267	54	)	)	PUNCT
aji-171	267	55	.	.	PUNCT
aji-171	268	1	the	the	DET
aji-171	268	2	examination	examination	NOUN
aji-171	268	3	of	of	ADP
aji-171	268	4	neurotransmitter	neurotransmitter	NOUN
aji-171	268	5	pathways	pathway	NOUN
aji-171	268	6	and	and	CCONJ
aji-171	268	7	metabolites	metabolite	NOUN
aji-171	268	8	associated	associate	VERB
aji-171	268	9	with	with	ADP
aji-171	268	10	the	the	DET
aji-171	268	11	gut	gut	NOUN
aji-171	268	12	-	-	PUNCT
aji-171	268	13	brain	brain	NOUN
aji-171	268	14	axis	axis	NOUN
aji-171	268	15	may	may	AUX
aji-171	268	16	yield	yield	VERB
aji-171	268	17	markers	marker	NOUN
aji-171	268	18	for	for	ADP
aji-171	268	19	the	the	DET
aji-171	268	20	biochemical	biochemical	ADJ
aji-171	268	21	underpinnings	underpinning	NOUN
aji-171	268	22	of	of	ADP
aji-171	268	23	mental	mental	ADJ
aji-171	268	24	health	health	NOUN
aji-171	268	25	disorders	disorder	NOUN
aji-171	268	26	,	,	PUNCT
aji-171	268	27	enabling	enable	VERB
aji-171	268	28	more	more	ADV
aji-171	268	29	precise	precise	ADJ
aji-171	268	30	diagnosis	diagnosis	NOUN
aji-171	268	31	and	and	CCONJ
aji-171	268	32	customized	customize	VERB
aji-171	268	33	treatment	treatment	NOUN
aji-171	268	34	plans	plan	NOUN
aji-171	268	35	.	.	PUNCT
aji-171	269	1	because	because	SCONJ
aji-171	269	2	they	they	PRON
aji-171	269	3	directly	directly	ADV
aji-171	269	4	affect	affect	VERB
aji-171	269	5	brain	brain	NOUN
aji-171	269	6	activity	activity	NOUN
aji-171	269	7	and	and	CCONJ
aji-171	269	8	mood	mood	NOUN
aji-171	269	9	regulation	regulation	NOUN
aji-171	269	10	,	,	PUNCT
aji-171	269	11	neurotransmitter	neurotransmitter	NOUN
aji-171	269	12	metabolites	metabolite	NOUN
aji-171	269	13	are	be	AUX
aji-171	269	14	significant	significant	ADJ
aji-171	269	15	in	in	ADP
aji-171	269	16	psychiatric	psychiatric	ADJ
aji-171	269	17	disorders	disorder	NOUN
aji-171	269	18	.	.	PUNCT
aji-171	270	1	for	for	ADP
aji-171	270	2	instance	instance	NOUN
aji-171	270	3	,	,	PUNCT
aji-171	270	4	serotonin	serotonin	VERB
aji-171	270	5	and	and	CCONJ
aji-171	270	6	its	its	PRON
aji-171	270	7	metabolite	metabolite	NOUN
aji-171	270	8	5hydroxyindoleacetic	5hydroxyindoleacetic	NUM
aji-171	270	9	acid	acid	NOUN
aji-171	270	10	(	(	PUNCT
aji-171	270	11	5	5	NUM
aji-171	270	12	-	-	PUNCT
aji-171	270	13	hiaa	hiaa	NOUN
aji-171	270	14	)	)	PUNCT
aji-171	270	15	is	be	AUX
aji-171	270	16	the	the	DET
aji-171	270	17	subject	subject	NOUN
aji-171	270	18	of	of	ADP
aji-171	270	19	much	much	ADJ
aji-171	270	20	research	research	NOUN
aji-171	270	21	in	in	ADP
aji-171	270	22	relation	relation	NOUN
aji-171	270	23	to	to	ADP
aji-171	270	24	mood	mood	NOUN
aji-171	270	25	disorders	disorder	NOUN
aji-171	270	26	(	(	PUNCT
aji-171	270	27	jayamohananan	jayamohananan	PROPN
aji-171	270	28	et	et	PROPN
aji-171	270	29	al	al	PROPN
aji-171	270	30	.	.	PROPN
aji-171	270	31	,	,	PUNCT
aji-171	270	32	2019	2019	NUM
aji-171	270	33	)	)	PUNCT
aji-171	270	34	.	.	PUNCT
aji-171	271	1	likewise	likewise	ADV
aji-171	271	2	,	,	PUNCT
aji-171	271	3	dopamine	dopamine	NOUN
aji-171	271	4	and	and	CCONJ
aji-171	271	5	homovanillic	homovanillic	PROPN
aji-171	271	6	acid	acid	NOUN
aji-171	271	7	dysregulation	dysregulation	NOUN
aji-171	271	8	is	be	AUX
aji-171	271	9	associated	associate	VERB
aji-171	271	10	with	with	ADP
aji-171	271	11	schizophrenia	schizophrenia	NOUN
aji-171	271	12	and	and	CCONJ
aji-171	271	13	bipolar	bipolar	ADJ
aji-171	271	14	disorder	disorder	NOUN
aji-171	271	15	(	(	PUNCT
aji-171	271	16	wada	wada	PROPN
aji-171	271	17	et	et	PROPN
aji-171	271	18	al	al	PROPN
aji-171	271	19	.	.	PROPN
aji-171	271	20	,	,	PUNCT
aji-171	271	21	2022	2022	NUM
aji-171	271	22	)	)	PUNCT
aji-171	271	23	,	,	PUNCT
aji-171	271	24	while	while	SCONJ
aji-171	271	25	depression	depression	NOUN
aji-171	271	26	is	be	AUX
aji-171	271	27	said	say	VERB
aji-171	271	28	to	to	PART
aji-171	271	29	be	be	AUX
aji-171	271	30	associated	associate	VERB
aji-171	271	31	with	with	ADP
aji-171	271	32	lower	low	ADJ
aji-171	271	33	levels	level	NOUN
aji-171	271	34	of	of	ADP
aji-171	271	35	serotonin	serotonin	NOUN
aji-171	271	36	and	and	CCONJ
aji-171	271	37	its	its	PRON
aji-171	271	38	metabolites	metabolite	NOUN
aji-171	271	39	(	(	PUNCT
aji-171	271	40	moncrieff	moncrieff	NOUN
aji-171	271	41	et	et	NOUN
aji-171	271	42	al	al	PROPN
aji-171	271	43	.	.	PROPN
aji-171	271	44	,	,	PUNCT
aji-171	271	45	2023	2023	NUM
aji-171	271	46	)	)	PUNCT
aji-171	271	47	.	.	PUNCT
aji-171	272	1	a	a	DET
aji-171	272	2	known	know	VERB
aji-171	272	3	inhibitory	inhibitory	ADJ
aji-171	272	4	neurotransmitter	neurotransmitter	NOUN
aji-171	272	5	,	,	PUNCT
aji-171	272	6	gamma	gamma	NOUN
aji-171	272	7	-	-	PUNCT
aji-171	272	8	aminobutyric	aminobutyric	ADJ
aji-171	272	9	acid	acid	NOUN
aji-171	272	10	(	(	PUNCT
aji-171	272	11	gaba	gaba	PROPN
aji-171	272	12	)	)	PUNCT
aji-171	272	13	,	,	PUNCT
aji-171	272	14	has	have	AUX
aji-171	272	15	been	be	AUX
aji-171	272	16	linked	link	VERB
aji-171	272	17	to	to	ADP
aji-171	272	18	symptoms	symptom	NOUN
aji-171	272	19	of	of	ADP
aji-171	272	20	anxiety	anxiety	NOUN
aji-171	272	21	and	and	CCONJ
aji-171	272	22	depression	depression	NOUN
aji-171	272	23	.	.	PUNCT
aji-171	273	1	variations	variation	NOUN
aji-171	273	2	in	in	ADP
aji-171	273	3	gaba	gaba	PROPN
aji-171	273	4	levels	level	NOUN
aji-171	273	5	reflect	reflect	VERB
aji-171	273	6	shifts	shift	NOUN
aji-171	273	7	in	in	ADP
aji-171	273	8	mood	mood	NOUN
aji-171	273	9	fig	fig	NOUN
aji-171	273	10	.	.	PUNCT
aji-171	274	1	3	3	X
aji-171	274	2	.	.	X
aji-171	274	3	potential	potential	ADJ
aji-171	274	4	pathways	pathway	NOUN
aji-171	274	5	through	through	ADP
aji-171	274	6	which	which	PRON
aji-171	274	7	scfas	scfas	NOUN
aji-171	274	8	influence	influence	NOUN
aji-171	274	9	gut	gut	NOUN
aji-171	274	10	–	–	PUNCT
aji-171	274	11	brain	brain	NOUN
aji-171	274	12	communication	communication	NOUN
aji-171	274	13	.	.	PUNCT
aji-171	275	1	copyright	copyright	NOUN
aji-171	275	2	frontiers	frontier	NOUN
aji-171	275	3	media	media	PROPN
aji-171	275	4	sa	sa	PROPN
aji-171	275	5	(	(	PUNCT
aji-171	275	6	2020	2020	NUM
aji-171	275	7	)	)	PUNCT
aji-171	275	8	(	(	PUNCT
aji-171	275	9	silva	silva	NOUN
aji-171	275	10	et	et	PROPN
aji-171	275	11	al	al	PROPN
aji-171	275	12	.	.	PROPN
aji-171	275	13	,	,	PUNCT
aji-171	275	14	2020	2020	NUM
aji-171	275	15	)	)	PUNCT
aji-171	275	16	mamman	mamman	NOUN
aji-171	275	17	et	et	PROPN
aji-171	275	18	al	al	PROPN
aji-171	275	19	.	.	PROPN
aji-171	275	20	;	;	PUNCT
aji-171	275	21	asian	asian	PROPN
aji-171	275	22	j.	j.	PROPN
aji-171	275	23	immunol	immunol	PROPN
aji-171	275	24	.	.	PROPN
aji-171	275	25	,	,	PUNCT
aji-171	275	26	vol	vol	NOUN
aji-171	275	27	.	.	PROPN
aji-171	275	28	8	8	NUM
aji-171	275	29	,	,	PUNCT
aji-171	275	30	no	no	INTJ
aji-171	275	31	.	.	NOUN
aji-171	275	32	1	1	NUM
aji-171	275	33	,	,	PUNCT
aji-171	275	34	pp	pp	ADJ
aji-171	275	35	.	.	PUNCT
aji-171	276	1	190	190	NUM
aji-171	276	2	-	-	SYM
aji-171	276	3	206	206	NUM
aji-171	276	4	,	,	PUNCT
aji-171	276	5	2025	2025	NUM
aji-171	276	6	;	;	PUNCT
aji-171	276	7	article	article	NOUN
aji-171	276	8	no.aji.140476	no.aji.140476	NOUN
aji-171	276	9	198	198	NUM
aji-171	276	10	regulation	regulation	NOUN
aji-171	276	11	and	and	CCONJ
aji-171	276	12	stress	stress	NOUN
aji-171	276	13	modulation	modulation	NOUN
aji-171	276	14	(	(	PUNCT
aji-171	276	15	prévot	prévot	PROPN
aji-171	276	16	and	and	CCONJ
aji-171	276	17	sibille	sibille	NOUN
aji-171	276	18	,	,	PUNCT
aji-171	276	19	2021	2021	NUM
aji-171	276	20	)	)	PUNCT
aji-171	276	21	.	.	PUNCT
aji-171	277	1	furthermore	furthermore	ADV
aji-171	277	2	,	,	PUNCT
aji-171	277	3	metabolites	metabolite	NOUN
aji-171	277	4	generated	generate	VERB
aji-171	277	5	by	by	ADP
aji-171	277	6	the	the	DET
aji-171	277	7	gut	gut	NOUN
aji-171	277	8	-	-	PUNCT
aji-171	277	9	brain	brain	NOUN
aji-171	277	10	axis	axis	NOUN
aji-171	277	11	are	be	AUX
aji-171	277	12	becoming	becoming	AUX
aji-171	277	13	more	more	ADV
aji-171	277	14	widely	widely	ADV
aji-171	277	15	acknowledged	acknowledge	VERB
aji-171	277	16	for	for	ADP
aji-171	277	17	their	their	PRON
aji-171	277	18	role	role	NOUN
aji-171	277	19	in	in	ADP
aji-171	277	20	mental	mental	ADJ
aji-171	277	21	health	health	NOUN
aji-171	277	22	(	(	PUNCT
aji-171	277	23	góralczyk	góralczyk	NOUN
aji-171	277	24	-	-	PUNCT
aji-171	277	25	bi	bi	NOUN
aji-171	277	26	´	´	NOUN
aji-171	277	27	nkowska	nkowska	PROPN
aji-171	277	28	et	et	PROPN
aji-171	277	29	al	al	PROPN
aji-171	277	30	.	.	PROPN
aji-171	277	31	,	,	PUNCT
aji-171	277	32	2022	2022	NUM
aji-171	277	33	)	)	PUNCT
aji-171	277	34	.	.	PUNCT
aji-171	278	1	intestinal	intestinal	ADJ
aji-171	278	2	microbiota	microbiota	NOUN
aji-171	278	3	activity	activity	NOUN
aji-171	278	4	produces	produce	VERB
aji-171	278	5	short	short	ADJ
aji-171	278	6	-	-	PUNCT
aji-171	278	7	chain	chain	NOUN
aji-171	278	8	fatty	fatty	NOUN
aji-171	278	9	acids	acid	NOUN
aji-171	278	10	(	(	PUNCT
aji-171	278	11	scfas	scfas	NOUN
aji-171	278	12	)	)	PUNCT
aji-171	278	13	,	,	PUNCT
aji-171	278	14	like	like	ADP
aji-171	278	15	butyrate	butyrate	NOUN
aji-171	278	16	and	and	CCONJ
aji-171	278	17	propionate	propionate	NOUN
aji-171	278	18	,	,	PUNCT
aji-171	278	19	which	which	DET
aji-171	278	20	impact	impact	NOUN
aji-171	278	21	neuroinflammation	neuroinflammation	NOUN
aji-171	278	22	,	,	PUNCT
aji-171	278	23	stress	stress	NOUN
aji-171	278	24	reactions	reaction	NOUN
aji-171	278	25	,	,	PUNCT
aji-171	278	26	and	and	CCONJ
aji-171	278	27	emotional	emotional	ADJ
aji-171	278	28	regulation	regulation	NOUN
aji-171	278	29	systems	system	NOUN
aji-171	278	30	(	(	PUNCT
aji-171	278	31	fig	fig	NOUN
aji-171	278	32	.	.	NOUN
aji-171	279	1	2	2	NUM
aji-171	279	2	)	)	PUNCT
aji-171	279	3	(	(	PUNCT
aji-171	279	4	silva	silva	NOUN
aji-171	279	5	et	et	PROPN
aji-171	279	6	al	al	PROPN
aji-171	279	7	.	.	PROPN
aji-171	279	8	,	,	PUNCT
aji-171	279	9	2020	2020	NUM
aji-171	279	10	)	)	PUNCT
aji-171	279	11	.	.	PUNCT
aji-171	280	1	given	give	VERB
aji-171	280	2	their	their	PRON
aji-171	280	3	role	role	NOUN
aji-171	280	4	in	in	ADP
aji-171	280	5	reducing	reduce	VERB
aji-171	280	6	inflammation	inflammation	NOUN
aji-171	280	7	and	and	CCONJ
aji-171	280	8	maintaining	maintain	VERB
aji-171	280	9	the	the	DET
aji-171	280	10	integrity	integrity	NOUN
aji-171	280	11	of	of	ADP
aji-171	280	12	the	the	DET
aji-171	280	13	blood	blood	NOUN
aji-171	280	14	-	-	PUNCT
aji-171	280	15	brain	brain	NOUN
aji-171	280	16	barrier	barrier	NOUN
aji-171	280	17	,	,	PUNCT
aji-171	280	18	low	low	ADJ
aji-171	280	19	levels	level	NOUN
aji-171	280	20	of	of	ADP
aji-171	280	21	scfas	scfas	NOUN
aji-171	280	22	have	have	AUX
aji-171	280	23	been	be	AUX
aji-171	280	24	proposed	propose	VERB
aji-171	280	25	to	to	PART
aji-171	280	26	be	be	AUX
aji-171	280	27	linked	link	VERB
aji-171	280	28	to	to	ADP
aji-171	280	29	anxiety	anxiety	NOUN
aji-171	280	30	and	and	CCONJ
aji-171	280	31	depression	depression	NOUN
aji-171	280	32	(	(	PUNCT
aji-171	280	33	silva	silva	NOUN
aji-171	280	34	et	et	PROPN
aji-171	280	35	al	al	PROPN
aji-171	280	36	.	.	PROPN
aji-171	280	37	,	,	PUNCT
aji-171	280	38	2020	2020	NUM
aji-171	280	39	)	)	PUNCT
aji-171	280	40	.	.	PUNCT
aji-171	281	1	tryptophan	tryptophan	NOUN
aji-171	281	2	and	and	CCONJ
aji-171	281	3	kynurenine	kynurenine	NOUN
aji-171	281	4	,	,	PUNCT
aji-171	281	5	two	two	NUM
aji-171	281	6	other	other	ADJ
aji-171	281	7	gut	gut	NOUN
aji-171	281	8	-	-	PUNCT
aji-171	281	9	derived	derive	VERB
aji-171	281	10	metabolites	metabolite	NOUN
aji-171	281	11	,	,	PUNCT
aji-171	281	12	have	have	AUX
aji-171	281	13	been	be	AUX
aji-171	281	14	linked	link	VERB
aji-171	281	15	to	to	ADP
aji-171	281	16	mood	mood	NOUN
aji-171	281	17	disorders	disorder	NOUN
aji-171	281	18	and	and	CCONJ
aji-171	281	19	schizophrenia	schizophrenia	NOUN
aji-171	281	20	and	and	CCONJ
aji-171	281	21	are	be	AUX
aji-171	281	22	linked	link	VERB
aji-171	281	23	to	to	ADP
aji-171	281	24	immunological	immunological	ADJ
aji-171	281	25	responses	response	NOUN
aji-171	281	26	and	and	CCONJ
aji-171	281	27	neurotransmitter	neurotransmitter	NOUN
aji-171	281	28	synthesis	synthesis	NOUN
aji-171	281	29	(	(	PUNCT
aji-171	281	30	marx	marx	PROPN
aji-171	281	31	et	et	PROPN
aji-171	281	32	al	al	PROPN
aji-171	281	33	.	.	PROPN
aji-171	281	34	,	,	PUNCT
aji-171	281	35	2021	2021	NUM
aji-171	281	36	)	)	PUNCT
aji-171	281	37	.	.	PUNCT
aji-171	282	1	not	not	PART
aji-171	282	2	only	only	ADV
aji-171	282	3	can	can	AUX
aji-171	282	4	these	these	DET
aji-171	282	5	metabolomic	metabolomic	ADJ
aji-171	282	6	biomarkers	biomarker	NOUN
aji-171	282	7	reveal	reveal	VERB
aji-171	282	8	the	the	DET
aji-171	282	9	biochemical	biochemical	ADJ
aji-171	282	10	foundations	foundation	NOUN
aji-171	282	11	of	of	ADP
aji-171	282	12	psychiatric	psychiatric	ADJ
aji-171	282	13	disorders	disorder	NOUN
aji-171	282	14	,	,	PUNCT
aji-171	282	15	but	but	CCONJ
aji-171	282	16	they	they	PRON
aji-171	282	17	will	will	AUX
aji-171	282	18	also	also	ADV
aji-171	282	19	enable	enable	VERB
aji-171	282	20	a	a	DET
aji-171	282	21	more	more	ADV
aji-171	282	22	individualized	individualized	ADJ
aji-171	282	23	approach	approach	NOUN
aji-171	282	24	to	to	ADP
aji-171	282	25	mental	mental	ADJ
aji-171	282	26	health	health	NOUN
aji-171	282	27	treatment	treatment	NOUN
aji-171	282	28	.	.	PUNCT
aji-171	283	1	continuous	continuous	ADJ
aji-171	283	2	monitoring	monitoring	NOUN
aji-171	283	3	of	of	ADP
aji-171	283	4	these	these	DET
aji-171	283	5	biomarkers	biomarker	NOUN
aji-171	283	6	would	would	AUX
aji-171	283	7	assist	assist	VERB
aji-171	283	8	medical	medical	ADJ
aji-171	283	9	professionals	professional	NOUN
aji-171	283	10	in	in	ADP
aji-171	283	11	streamlining	streamline	VERB
aji-171	283	12	diagnostics	diagnostic	NOUN
aji-171	283	13	,	,	PUNCT
aji-171	283	14	customizing	customizing	NOUN
aji-171	283	15	treatments	treatment	NOUN
aji-171	283	16	,	,	PUNCT
aji-171	283	17	and	and	CCONJ
aji-171	283	18	probably	probably	ADV
aji-171	283	19	improving	improve	VERB
aji-171	283	20	patient	patient	ADJ
aji-171	283	21	outcomes	outcome	NOUN
aji-171	283	22	by	by	ADP
aji-171	283	23	providing	provide	VERB
aji-171	283	24	more	more	ADV
aji-171	283	25	targeted	target	VERB
aji-171	283	26	interventions	intervention	NOUN
aji-171	283	27	(	(	PUNCT
aji-171	283	28	marx	marx	PROPN
aji-171	283	29	et	et	PROPN
aji-171	283	30	al	al	PROPN
aji-171	283	31	.	.	PROPN
aji-171	283	32	,	,	PUNCT
aji-171	283	33	2021	2021	NUM
aji-171	283	34	)	)	PUNCT
aji-171	283	35	.	.	PUNCT
aji-171	284	1	4.3	4.3	NUM
aji-171	284	2	potential	potential	ADJ
aji-171	284	3	early	early	ADJ
aji-171	284	4	diagnosis	diagnosis	NOUN
aji-171	284	5	biomarkers	biomarker	NOUN
aji-171	284	6	for	for	ADP
aji-171	284	7	mental	mental	ADJ
aji-171	284	8	health	health	NOUN
aji-171	284	9	and	and	CCONJ
aji-171	284	10	neurodegenerative	neurodegenerative	ADJ
aji-171	284	11	diseases	disease	NOUN
aji-171	284	12	in	in	ADP
aji-171	284	13	the	the	DET
aji-171	284	14	diagnosis	diagnosis	NOUN
aji-171	284	15	and	and	CCONJ
aji-171	284	16	treatment	treatment	NOUN
aji-171	284	17	planning	planning	NOUN
aji-171	284	18	of	of	ADP
aji-171	284	19	neurological	neurological	ADJ
aji-171	284	20	and	and	CCONJ
aji-171	284	21	psychiatric	psychiatric	ADJ
aji-171	284	22	disorders	disorder	NOUN
aji-171	284	23	,	,	PUNCT
aji-171	284	24	biomarkers	biomarker	NOUN
aji-171	284	25	based	base	VERB
aji-171	284	26	on	on	ADP
aji-171	284	27	metabolomics	metabolomic	NOUN
aji-171	284	28	hold	hold	VERB
aji-171	284	29	great	great	ADJ
aji-171	284	30	promise	promise	NOUN
aji-171	284	31	(	(	PUNCT
aji-171	284	32	török	török	PROPN
aji-171	284	33	et	et	PROPN
aji-171	284	34	al	al	PROPN
aji-171	284	35	.	.	PROPN
aji-171	284	36	,	,	PUNCT
aji-171	284	37	2020	2020	NUM
aji-171	284	38	;	;	PUNCT
aji-171	284	39	mallu	mallu	PROPN
aji-171	284	40	et	et	PROPN
aji-171	284	41	al	al	PROPN
aji-171	284	42	.	.	PROPN
aji-171	284	43	,	,	PUNCT
aji-171	284	44	2021	2021	NUM
aji-171	284	45	)	)	PUNCT
aji-171	284	46	.	.	PUNCT
aji-171	285	1	through	through	ADP
aji-171	285	2	the	the	DET
aji-171	285	3	identification	identification	NOUN
aji-171	285	4	of	of	ADP
aji-171	285	5	particular	particular	ADJ
aji-171	285	6	metabolic	metabolic	NOUN
aji-171	285	7	alterations	alteration	NOUN
aji-171	285	8	that	that	PRON
aji-171	285	9	take	take	VERB
aji-171	285	10	place	place	NOUN
aji-171	285	11	even	even	ADV
aji-171	285	12	prior	prior	ADV
aji-171	285	13	to	to	ADP
aji-171	285	14	the	the	DET
aji-171	285	15	manifestation	manifestation	NOUN
aji-171	285	16	of	of	ADP
aji-171	285	17	clinical	clinical	ADJ
aji-171	285	18	symptoms	symptom	NOUN
aji-171	285	19	,	,	PUNCT
aji-171	285	20	these	these	DET
aji-171	285	21	biomarkers	biomarker	NOUN
aji-171	285	22	are	be	AUX
aji-171	285	23	anticipated	anticipate	VERB
aji-171	285	24	to	to	PART
aji-171	285	25	aid	aid	VERB
aji-171	285	26	in	in	ADP
aji-171	285	27	early	early	ADJ
aji-171	285	28	intervention	intervention	NOUN
aji-171	285	29	,	,	PUNCT
aji-171	285	30	improving	improve	VERB
aji-171	285	31	the	the	DET
aji-171	285	32	prognosis	prognosis	NOUN
aji-171	285	33	by	by	ADP
aji-171	285	34	delaying	delay	VERB
aji-171	285	35	the	the	DET
aji-171	285	36	course	course	NOUN
aji-171	285	37	of	of	ADP
aji-171	285	38	the	the	DET
aji-171	285	39	disease	disease	NOUN
aji-171	285	40	(	(	PUNCT
aji-171	285	41	sun	sun	PROPN
aji-171	285	42	et	et	PROPN
aji-171	285	43	al	al	PROPN
aji-171	285	44	.	.	PROPN
aji-171	285	45	,	,	PUNCT
aji-171	285	46	2023	2023	NUM
aji-171	285	47	)	)	PUNCT
aji-171	285	48	.	.	PUNCT
aji-171	286	1	they	they	PRON
aji-171	286	2	are	be	AUX
aji-171	286	3	useful	useful	ADJ
aji-171	286	4	for	for	ADP
aji-171	286	5	early	early	ADJ
aji-171	286	6	diagnosis	diagnosis	NOUN
aji-171	286	7	because	because	SCONJ
aji-171	286	8	,	,	PUNCT
aji-171	286	9	for	for	ADP
aji-171	286	10	example	example	NOUN
aji-171	286	11	,	,	PUNCT
aji-171	286	12	a	a	DET
aji-171	286	13	preclinical	preclinical	ADJ
aji-171	286	14	stage	stage	NOUN
aji-171	286	15	of	of	ADP
aji-171	286	16	the	the	DET
aji-171	286	17	disease	disease	NOUN
aji-171	286	18	has	have	AUX
aji-171	286	19	been	be	AUX
aji-171	286	20	noted	note	VERB
aji-171	286	21	in	in	ADP
aji-171	286	22	which	which	PRON
aji-171	286	23	ad	ad	NOUN
aji-171	286	24	patients	patient	NOUN
aji-171	286	25	exhibit	exhibit	VERB
aji-171	286	26	elevated	elevated	ADJ
aji-171	286	27	myo	myo	NOUN
aji-171	286	28	-	-	PUNCT
aji-171	286	29	inositol	inositol	NOUN
aji-171	286	30	and	and	CCONJ
aji-171	286	31	alterations	alteration	NOUN
aji-171	286	32	in	in	ADP
aji-171	286	33	phospholipid	phospholipid	NOUN
aji-171	286	34	profiles	profile	NOUN
aji-171	286	35	(	(	PUNCT
aji-171	286	36	ahanger	ahanger	PROPN
aji-171	286	37	et	et	PROPN
aji-171	286	38	al	al	PROPN
aji-171	286	39	.	.	PROPN
aji-171	286	40	,	,	PUNCT
aji-171	286	41	2024	2024	NUM
aji-171	286	42	)	)	PUNCT
aji-171	286	43	.	.	PUNCT
aji-171	287	1	if	if	SCONJ
aji-171	287	2	these	these	DET
aji-171	287	3	biomarkers	biomarker	NOUN
aji-171	287	4	are	be	AUX
aji-171	287	5	discovered	discover	VERB
aji-171	287	6	early	early	ADV
aji-171	287	7	,	,	PUNCT
aji-171	287	8	prompt	prompt	ADJ
aji-171	287	9	interventions	intervention	NOUN
aji-171	287	10	that	that	PRON
aji-171	287	11	postpone	postpone	VERB
aji-171	287	12	cognitive	cognitive	ADJ
aji-171	287	13	decline	decline	NOUN
aji-171	287	14	will	will	AUX
aji-171	287	15	be	be	AUX
aji-171	287	16	possible	possible	ADJ
aji-171	287	17	.	.	PUNCT
aji-171	288	1	metabolomics	metabolomic	NOUN
aji-171	288	2	as	as	ADP
aji-171	288	3	a	a	DET
aji-171	288	4	foundation	foundation	NOUN
aji-171	288	5	for	for	ADP
aji-171	288	6	biomarker	biomarker	NOUN
aji-171	288	7	discovery	discovery	NOUN
aji-171	288	8	for	for	ADP
aji-171	288	9	the	the	DET
aji-171	288	10	early	early	ADJ
aji-171	288	11	diagnosis	diagnosis	NOUN
aji-171	288	12	of	of	ADP
aji-171	288	13	psychiatric	psychiatric	ADJ
aji-171	288	14	and	and	CCONJ
aji-171	288	15	neurodegenerative	neurodegenerative	ADJ
aji-171	288	16	disorders	disorder	NOUN
aji-171	288	17	has	have	AUX
aji-171	288	18	produced	produce	VERB
aji-171	288	19	very	very	ADV
aji-171	288	20	encouraging	encouraging	ADJ
aji-171	288	21	results	result	NOUN
aji-171	288	22	in	in	ADP
aji-171	288	23	clinical	clinical	ADJ
aji-171	288	24	studies	study	NOUN
aji-171	288	25	.	.	PUNCT
aji-171	289	1	alpha	alpha	NOUN
aji-171	289	2	-	-	PUNCT
aji-171	289	3	synuclein	synuclein	NOUN
aji-171	289	4	aggregates	aggregate	NOUN
aji-171	289	5	and	and	CCONJ
aji-171	289	6	urates	urate	NOUN
aji-171	289	7	have	have	AUX
aji-171	289	8	been	be	AUX
aji-171	289	9	identified	identify	VERB
aji-171	289	10	as	as	ADP
aji-171	289	11	interesting	interesting	ADJ
aji-171	289	12	early	early	ADJ
aji-171	289	13	indicators	indicator	NOUN
aji-171	289	14	of	of	ADP
aji-171	289	15	parkinson	parkinson	NOUN
aji-171	289	16	's	's	PART
aji-171	289	17	disease	disease	NOUN
aji-171	289	18	(	(	PUNCT
aji-171	289	19	pd	pd	NOUN
aji-171	289	20	)	)	PUNCT
aji-171	289	21	due	due	ADP
aji-171	289	22	to	to	ADP
aji-171	289	23	their	their	PRON
aji-171	289	24	lower	low	ADJ
aji-171	289	25	levels	level	NOUN
aji-171	289	26	in	in	ADP
aji-171	289	27	csf	csf	ADJ
aji-171	289	28	(	(	PUNCT
aji-171	289	29	ganguly	ganguly	PROPN
aji-171	289	30	et	et	PROPN
aji-171	289	31	al	al	PROPN
aji-171	289	32	.	.	PROPN
aji-171	289	33	,	,	PUNCT
aji-171	289	34	2021	2021	NUM
aji-171	289	35	)	)	PUNCT
aji-171	289	36	.	.	PUNCT
aji-171	290	1	according	accord	VERB
aji-171	290	2	to	to	ADP
aji-171	290	3	averina	averina	PROPN
aji-171	290	4	et	et	PROPN
aji-171	290	5	al	al	PROPN
aji-171	290	6	.	.	PROPN
aji-171	291	1	(	(	PUNCT
aji-171	291	2	2024	2024	NUM
aji-171	291	3	)	)	PUNCT
aji-171	291	4	,	,	PUNCT
aji-171	291	5	depression	depression	NOUN
aji-171	291	6	and	and	CCONJ
aji-171	291	7	schizophrenia	schizophrenia	NOUN
aji-171	291	8	have	have	AUX
aji-171	291	9	been	be	AUX
aji-171	291	10	linked	link	VERB
aji-171	291	11	to	to	ADP
aji-171	291	12	alterations	alteration	NOUN
aji-171	291	13	in	in	ADP
aji-171	291	14	serotonin	serotonin	NOUN
aji-171	291	15	and	and	CCONJ
aji-171	291	16	dopamine	dopamine	NOUN
aji-171	291	17	metabolism	metabolism	NOUN
aji-171	291	18	.	.	PUNCT
aji-171	292	1	moreover	moreover	ADV
aji-171	292	2	,	,	PUNCT
aji-171	292	3	increased	increase	VERB
aji-171	292	4	kynurenic	kynurenic	ADJ
aji-171	292	5	acid	acid	NOUN
aji-171	292	6	levels	level	NOUN
aji-171	292	7	are	be	AUX
aji-171	292	8	associated	associate	VERB
aji-171	292	9	with	with	ADP
aji-171	292	10	oxidative	oxidative	ADJ
aji-171	292	11	stress	stress	NOUN
aji-171	292	12	and	and	CCONJ
aji-171	292	13	neuroinflammation	neuroinflammation	NOUN
aji-171	292	14	,	,	PUNCT
aji-171	292	15	providing	provide	VERB
aji-171	292	16	insight	insight	NOUN
aji-171	292	17	into	into	ADP
aji-171	292	18	the	the	DET
aji-171	292	19	early	early	ADJ
aji-171	292	20	phases	phase	NOUN
aji-171	292	21	of	of	ADP
aji-171	292	22	mood	mood	NOUN
aji-171	292	23	disorders	disorder	NOUN
aji-171	292	24	and	and	CCONJ
aji-171	292	25	schizophrenia	schizophrenia	NOUN
aji-171	292	26	(	(	PUNCT
aji-171	292	27	o'farrell	o'farrell	PROPN
aji-171	292	28	and	and	CCONJ
aji-171	292	29	harkin	harkin	X
aji-171	292	30	,	,	PUNCT
aji-171	292	31	2017	2017	NUM
aji-171	292	32	;	;	PUNCT
aji-171	292	33	mor	mor	ADV
aji-171	292	34	,	,	PUNCT
aji-171	292	35	et	et	PROPN
aji-171	292	36	al	al	PROPN
aji-171	292	37	.	.	PROPN
aji-171	292	38	,	,	PUNCT
aji-171	292	39	2021	2021	NUM
aji-171	292	40	)	)	PUNCT
aji-171	292	41	.	.	PUNCT
aji-171	293	1	these	these	DET
aji-171	293	2	gut	gut	NOUN
aji-171	293	3	-	-	PUNCT
aji-171	293	4	brain	brain	NOUN
aji-171	293	5	axis	axis	NOUN
aji-171	293	6	-	-	PUNCT
aji-171	293	7	derived	derive	VERB
aji-171	293	8	altered	altered	ADJ
aji-171	293	9	scfas	scfas	NOUN
aji-171	293	10	are	be	AUX
aji-171	293	11	emerging	emerge	VERB
aji-171	293	12	as	as	ADP
aji-171	293	13	promising	promise	VERB
aji-171	293	14	biomarkers	biomarker	NOUN
aji-171	293	15	for	for	ADP
aji-171	293	16	mental	mental	ADJ
aji-171	293	17	health	health	NOUN
aji-171	293	18	conditions	condition	NOUN
aji-171	293	19	,	,	PUNCT
aji-171	293	20	particularly	particularly	ADV
aji-171	293	21	depression	depression	NOUN
aji-171	293	22	(	(	PUNCT
aji-171	293	23	o'riordan	o'riordan	PROPN
aji-171	293	24	et	et	PROPN
aji-171	293	25	al	al	PROPN
aji-171	293	26	.	.	PROPN
aji-171	293	27	,	,	PUNCT
aji-171	293	28	2022	2022	NUM
aji-171	293	29	)	)	PUNCT
aji-171	293	30	.	.	PUNCT
aji-171	294	1	furthermore	furthermore	ADV
aji-171	294	2	,	,	PUNCT
aji-171	294	3	als	al	NOUN
aji-171	294	4	and	and	CCONJ
aji-171	294	5	ms	ms	NOUN
aji-171	294	6	can	can	AUX
aji-171	294	7	be	be	AUX
aji-171	294	8	accurately	accurately	ADV
aji-171	294	9	diagnosed	diagnose	VERB
aji-171	294	10	early	early	ADJ
aji-171	294	11	thanks	thank	NOUN
aji-171	294	12	to	to	ADP
aji-171	294	13	neurofilament	neurofilament	ADJ
aji-171	294	14	light	light	ADJ
aji-171	294	15	chain	chain	NOUN
aji-171	294	16	levels	level	NOUN
aji-171	294	17	in	in	ADP
aji-171	294	18	als	als	NOUN
aji-171	294	19	and	and	CCONJ
aji-171	294	20	sphingomyelin	sphingomyelin	NOUN
aji-171	294	21	reductions	reduction	NOUN
aji-171	294	22	in	in	ADP
aji-171	294	23	ms	ms	PROPN
aji-171	294	24	(	(	PUNCT
aji-171	294	25	yang	yang	PROPN
aji-171	294	26	et	et	PROPN
aji-171	294	27	al	al	PROPN
aji-171	294	28	.	.	PROPN
aji-171	294	29	,	,	PUNCT
aji-171	294	30	2022	2022	NUM
aji-171	294	31	)	)	PUNCT
aji-171	294	32	.	.	PUNCT
aji-171	295	1	according	accord	VERB
aji-171	295	2	to	to	ADP
aji-171	295	3	sacchet	sacchet	NOUN
aji-171	295	4	et	et	PROPN
aji-171	295	5	al	al	PROPN
aji-171	295	6	.	.	PROPN
aji-171	296	1	(	(	PUNCT
aji-171	296	2	2024	2024	NUM
aji-171	296	3	)	)	PUNCT
aji-171	296	4	,	,	PUNCT
aji-171	296	5	elevated	elevated	ADJ
aji-171	296	6	cortisol	cortisol	ADJ
aji-171	296	7	levels	level	NOUN
aji-171	296	8	in	in	ADP
aji-171	296	9	anxiety	anxiety	NOUN
aji-171	296	10	disorders	disorder	NOUN
aji-171	296	11	raise	raise	VERB
aji-171	296	12	the	the	DET
aji-171	296	13	risk	risk	NOUN
aji-171	296	14	and	and	CCONJ
aji-171	296	15	help	help	VERB
aji-171	296	16	make	make	VERB
aji-171	296	17	a	a	DET
aji-171	296	18	diagnosis	diagnosis	NOUN
aji-171	296	19	even	even	ADV
aji-171	296	20	before	before	SCONJ
aji-171	296	21	all	all	DET
aji-171	296	22	symptoms	symptom	NOUN
aji-171	296	23	appear	appear	VERB
aji-171	296	24	.	.	PUNCT
aji-171	297	1	in	in	ADP
aji-171	297	2	addition	addition	NOUN
aji-171	297	3	to	to	ADP
aji-171	297	4	offering	offer	VERB
aji-171	297	5	tools	tool	NOUN
aji-171	297	6	for	for	ADP
aji-171	297	7	early	early	ADJ
aji-171	297	8	detection	detection	NOUN
aji-171	297	9	,	,	PUNCT
aji-171	297	10	these	these	DET
aji-171	297	11	biomarkers	biomarker	NOUN
aji-171	297	12	also	also	ADV
aji-171	297	13	enable	enable	VERB
aji-171	297	14	the	the	DET
aji-171	297	15	application	application	NOUN
aji-171	297	16	of	of	ADP
aji-171	297	17	tailored	tailor	VERB
aji-171	297	18	treatment	treatment	NOUN
aji-171	297	19	to	to	PART
aji-171	297	20	enhance	enhance	VERB
aji-171	297	21	prognosis	prognosis	NOUN
aji-171	297	22	and	and	CCONJ
aji-171	297	23	impede	impede	VERB
aji-171	297	24	the	the	DET
aji-171	297	25	progression	progression	NOUN
aji-171	297	26	of	of	ADP
aji-171	297	27	disease	disease	NOUN
aji-171	297	28	.	.	PUNCT
aji-171	298	1	early	early	ADJ
aji-171	298	2	detection	detection	NOUN
aji-171	298	3	of	of	ADP
aji-171	298	4	mental	mental	ADJ
aji-171	298	5	health	health	NOUN
aji-171	298	6	conditions	condition	NOUN
aji-171	298	7	enables	enable	VERB
aji-171	298	8	physicians	physician	NOUN
aji-171	298	9	to	to	PART
aji-171	298	10	use	use	VERB
aji-171	298	11	treatment	treatment	NOUN
aji-171	298	12	plans	plan	NOUN
aji-171	298	13	based	base	VERB
aji-171	298	14	on	on	ADP
aji-171	298	15	individual	individual	ADJ
aji-171	298	16	biochemical	biochemical	ADJ
aji-171	298	17	profiles	profile	NOUN
aji-171	298	18	that	that	PRON
aji-171	298	19	optimize	optimize	VERB
aji-171	298	20	an	an	DET
aji-171	298	21	intervention	intervention	NOUN
aji-171	298	22	's	's	PART
aji-171	298	23	efficacy	efficacy	NOUN
aji-171	298	24	(	(	PUNCT
aji-171	298	25	sacchet	sacchet	NOUN
aji-171	298	26	et	et	PROPN
aji-171	298	27	al	al	PROPN
aji-171	298	28	.	.	PROPN
aji-171	298	29	,	,	PUNCT
aji-171	298	30	2024	2024	NUM
aji-171	298	31	)	)	PUNCT
aji-171	298	32	.	.	PUNCT
aji-171	299	1	it	it	PRON
aji-171	299	2	is	be	AUX
aji-171	299	3	hoped	hope	VERB
aji-171	299	4	that	that	SCONJ
aji-171	299	5	the	the	DET
aji-171	299	6	use	use	NOUN
aji-171	299	7	of	of	ADP
aji-171	299	8	metabolomics	metabolomic	NOUN
aji-171	299	9	-	-	PUNCT
aji-171	299	10	based	base	VERB
aji-171	299	11	biomarkers	biomarker	NOUN
aji-171	299	12	will	will	AUX
aji-171	299	13	eventually	eventually	ADV
aji-171	299	14	lead	lead	VERB
aji-171	299	15	to	to	ADP
aji-171	299	16	a	a	DET
aji-171	299	17	paradigm	paradigm	NOUN
aji-171	299	18	shift	shift	NOUN
aji-171	299	19	in	in	ADP
aji-171	299	20	how	how	SCONJ
aji-171	299	21	doctors	doctor	NOUN
aji-171	299	22	choose	choose	VERB
aji-171	299	23	treatments	treatment	NOUN
aji-171	299	24	that	that	PRON
aji-171	299	25	are	be	AUX
aji-171	299	26	specific	specific	ADJ
aji-171	299	27	to	to	ADP
aji-171	299	28	each	each	DET
aji-171	299	29	patient	patient	NOUN
aji-171	299	30	and	and	CCONJ
aji-171	299	31	diagnose	diagnose	NOUN
aji-171	299	32	illnesses	illness	NOUN
aji-171	299	33	early	early	ADV
aji-171	299	34	.	.	PUNCT
aji-171	300	1	this	this	PRON
aji-171	300	2	will	will	AUX
aji-171	300	3	improve	improve	VERB
aji-171	300	4	patient	patient	ADJ
aji-171	300	5	outcomes	outcome	NOUN
aji-171	300	6	by	by	ADP
aji-171	300	7	more	more	ADV
aji-171	300	8	effectively	effectively	ADV
aji-171	300	9	managing	manage	VERB
aji-171	300	10	psychiatric	psychiatric	ADJ
aji-171	300	11	and	and	CCONJ
aji-171	300	12	neurodegenerative	neurodegenerative	ADJ
aji-171	300	13	conditions	condition	NOUN
aji-171	300	14	(	(	PUNCT
aji-171	300	15	sacchet	sacchet	NOUN
aji-171	300	16	et	et	PROPN
aji-171	300	17	al	al	PROPN
aji-171	300	18	.	.	PROPN
aji-171	300	19	,	,	PUNCT
aji-171	300	20	2024	2024	NUM
aji-171	300	21	)	)	PUNCT
aji-171	300	22	.	.	PUNCT
aji-171	301	1	5	5	X
aji-171	301	2	.	.	X
aji-171	301	3	disease	disease	NOUN
aji-171	301	4	and	and	CCONJ
aji-171	301	5	health	health	NOUN
aji-171	301	6	metabolomics	metabolomic	NOUN
aji-171	301	7	applications	application	NOUN
aji-171	301	8	of	of	ADP
aji-171	301	9	metabolomics	metabolomic	NOUN
aji-171	301	10	in	in	ADP
aji-171	301	11	health	health	NOUN
aji-171	301	12	and	and	CCONJ
aji-171	301	13	disease	disease	NOUN
aji-171	301	14	include	include	VERB
aji-171	301	15	single	single	ADJ
aji-171	301	16	-	-	PUNCT
aji-171	301	17	cell	cell	NOUN
aji-171	301	18	,	,	PUNCT
aji-171	301	19	epidemiologic	epidemiologic	ADJ
aji-171	301	20	population	population	NOUN
aji-171	301	21	studies	study	NOUN
aji-171	301	22	,	,	PUNCT
aji-171	301	23	metabolic	metabolic	NOUN
aji-171	301	24	phenotyping	phenotyping	NOUN
aji-171	301	25	,	,	PUNCT
aji-171	301	26	metabolome	metabolome	NOUN
aji-171	301	27	-	-	PUNCT
aji-171	301	28	wide	wide	ADJ
aji-171	301	29	association	association	NOUN
aji-171	301	30	studies	study	NOUN
aji-171	301	31	(	(	PUNCT
aji-171	301	32	mwas	mwas	NOUN
aji-171	301	33	)	)	PUNCT
aji-171	301	34	,	,	PUNCT
aji-171	301	35	precision	precision	NOUN
aji-171	301	36	metabolomics	metabolomic	NOUN
aji-171	301	37	,	,	PUNCT
aji-171	301	38	and	and	CCONJ
aji-171	301	39	integrative	integrative	ADJ
aji-171	301	40	metabolomics	metabolomic	NOUN
aji-171	301	41	,	,	PUNCT
aji-171	301	42	which	which	PRON
aji-171	301	43	is	be	AUX
aji-171	301	44	the	the	DET
aji-171	301	45	use	use	NOUN
aji-171	301	46	of	of	ADP
aji-171	301	47	metabolomics	metabolomic	NOUN
aji-171	301	48	in	in	ADP
aji-171	301	49	conjunction	conjunction	NOUN
aji-171	301	50	with	with	ADP
aji-171	301	51	other	other	ADJ
aji-171	301	52	omics	omic	NOUN
aji-171	301	53	disciplines	discipline	NOUN
aji-171	301	54	(	(	PUNCT
aji-171	301	55	dalamaga	dalamaga	NOUN
aji-171	301	56	,	,	PUNCT
aji-171	301	57	2024).live	2024).live	NUM
aji-171	301	58	single	single	ADJ
aji-171	301	59	-	-	PUNCT
aji-171	301	60	cell	cell	NOUN
aji-171	301	61	mass	mass	NOUN
aji-171	301	62	spectrometry	spectrometry	NOUN
aji-171	301	63	(	(	PUNCT
aji-171	301	64	lscms	lscms	PROPN
aji-171	301	65	)	)	PUNCT
aji-171	301	66	,	,	PUNCT
aji-171	301	67	lc	lc	PROPN
aji-171	301	68	-	-	PUNCT
aji-171	301	69	ms	ms	PROPN
aji-171	301	70	/	/	SYM
aji-171	301	71	ms	ms	PROPN
aji-171	301	72	,	,	PUNCT
aji-171	301	73	gc	gc	PROPN
aji-171	301	74	-	-	PUNCT
aji-171	301	75	ms	ms	PROPN
aji-171	301	76	/	/	SYM
aji-171	301	77	ms	ms	PROPN
aji-171	301	78	,	,	PUNCT
aji-171	301	79	mamman	mamman	NOUN
aji-171	301	80	et	et	PROPN
aji-171	301	81	al	al	PROPN
aji-171	301	82	.	.	PROPN
aji-171	301	83	;	;	PUNCT
aji-171	302	1	asian	asian	PROPN
aji-171	302	2	j.	j.	PROPN
aji-171	302	3	immunol	immunol	PROPN
aji-171	302	4	.	.	PROPN
aji-171	302	5	,	,	PUNCT
aji-171	302	6	vol	vol	NOUN
aji-171	302	7	.	.	PROPN
aji-171	302	8	8	8	NUM
aji-171	302	9	,	,	PUNCT
aji-171	302	10	no	no	INTJ
aji-171	302	11	.	.	NOUN
aji-171	302	12	1	1	NUM
aji-171	302	13	,	,	PUNCT
aji-171	302	14	pp	pp	ADJ
aji-171	302	15	.	.	PUNCT
aji-171	303	1	190	190	NUM
aji-171	303	2	-	-	SYM
aji-171	303	3	206	206	NUM
aji-171	303	4	,	,	PUNCT
aji-171	303	5	2025	2025	NUM
aji-171	303	6	;	;	PUNCT
aji-171	303	7	article	article	NOUN
aji-171	303	8	no.aji.140476	no.aji.140476	X
aji-171	303	9	199	199	NUM
aji-171	303	10	and	and	CCONJ
aji-171	303	11	single	single	ADJ
aji-171	303	12	-	-	PUNCT
aji-171	303	13	cell	cell	NOUN
aji-171	303	14	metabolomics	metabolomic	NOUN
aji-171	303	15	and	and	CCONJ
aji-171	303	16	lipidomics	lipidomic	NOUN
aji-171	303	17	technologies	technology	NOUN
aji-171	303	18	enable	enable	VERB
aji-171	303	19	high	high	ADJ
aji-171	303	20	-	-	PUNCT
aji-171	303	21	dimensional	dimensional	ADJ
aji-171	303	22	characterizations	characterization	NOUN
aji-171	303	23	of	of	ADP
aji-171	303	24	individual	individual	ADJ
aji-171	303	25	cells	cell	NOUN
aji-171	303	26	,	,	PUNCT
aji-171	303	27	disease	disease	NOUN
aji-171	303	28	heterogeneity	heterogeneity	NOUN
aji-171	303	29	and	and	CCONJ
aji-171	303	30	complexity	complexity	NOUN
aji-171	303	31	,	,	PUNCT
aji-171	303	32	and	and	CCONJ
aji-171	303	33	the	the	DET
aji-171	303	34	identification	identification	NOUN
aji-171	303	35	,	,	PUNCT
aji-171	303	36	expression	expression	NOUN
aji-171	303	37	,	,	PUNCT
aji-171	303	38	and	and	CCONJ
aji-171	303	39	abundance	abundance	NOUN
aji-171	303	40	of	of	ADP
aji-171	303	41	disease	disease	NOUN
aji-171	303	42	-	-	PUNCT
aji-171	303	43	associated	associate	VERB
aji-171	303	44	metabolites	metabolite	NOUN
aji-171	303	45	and	and	CCONJ
aji-171	303	46	small	small	ADJ
aji-171	303	47	mole	mole	NOUN
aji-171	303	48	cules	cule	NOUN
aji-171	303	49	(	(	PUNCT
aji-171	303	50	lempesis	lempesis	NOUN
aji-171	303	51	et	et	PROPN
aji-171	303	52	al	al	PROPN
aji-171	303	53	.	.	PROPN
aji-171	303	54	,	,	PUNCT
aji-171	303	55	2022	2022	NUM
aji-171	303	56	)	)	PUNCT
aji-171	303	57	.	.	PUNCT
aji-171	304	1	cell	cell	NOUN
aji-171	304	2	-	-	PUNCT
aji-171	304	3	cell	cell	NOUN
aji-171	304	4	interactions	interaction	NOUN
aji-171	304	5	and	and	CCONJ
aji-171	304	6	tumor	tumor	NOUN
aji-171	304	7	heterogeneity	heterogeneity	NOUN
aji-171	304	8	were	be	AUX
aji-171	304	9	discovered	discover	VERB
aji-171	304	10	through	through	ADP
aji-171	304	11	imaging	image	VERB
aji-171	304	12	ms	ms	NOUN
aji-171	304	13	analysis	analysis	NOUN
aji-171	304	14	of	of	ADP
aji-171	304	15	human	human	ADJ
aji-171	304	16	breast	breast	NOUN
aji-171	304	17	cancer	cancer	NOUN
aji-171	304	18	samples	sample	NOUN
aji-171	304	19	at	at	ADP
aji-171	304	20	the	the	DET
aji-171	304	21	single	single	ADJ
aji-171	304	22	-	-	PUNCT
aji-171	304	23	cell	cell	NOUN
aji-171	304	24	level	level	NOUN
aji-171	304	25	(	(	PUNCT
aji-171	304	26	lempesis	lempesis	NOUN
aji-171	304	27	et	et	PROPN
aji-171	304	28	al	al	PROPN
aji-171	304	29	.	.	PROPN
aji-171	304	30	,	,	PUNCT
aji-171	304	31	2022	2022	NUM
aji-171	304	32	)	)	PUNCT
aji-171	304	33	.	.	PUNCT
aji-171	305	1	metabolomics	metabolomic	NOUN
aji-171	305	2	fingerprinting	fingerprint	VERB
aji-171	305	3	and	and	CCONJ
aji-171	305	4	footprinting	footprinte	VERB
aji-171	305	5	techniques	technique	NOUN
aji-171	305	6	,	,	PUNCT
aji-171	305	7	mwas	mwas	ADV
aji-171	305	8	,	,	PUNCT
aji-171	305	9	and	and	CCONJ
aji-171	305	10	clinical	clinical	ADJ
aji-171	305	11	biomarkers	biomarker	NOUN
aji-171	305	12	and	and	CCONJ
aji-171	305	13	various	various	ADJ
aji-171	305	14	metabotypes	metabotype	NOUN
aji-171	305	15	of	of	ADP
aji-171	305	16	disease	disease	NOUN
aji-171	305	17	severity	severity	NOUN
aji-171	305	18	correlated	correlate	VERB
aji-171	305	19	to	to	ADP
aji-171	305	20	exposures	exposure	NOUN
aji-171	305	21	(	(	PUNCT
aji-171	305	22	zhang	zhang	X
aji-171	305	23	et	et	PROPN
aji-171	305	24	al	al	PROPN
aji-171	305	25	.	.	PROPN
aji-171	305	26	,	,	PUNCT
aji-171	305	27	2023	2023	NUM
aji-171	305	28	)	)	PUNCT
aji-171	305	29	and	and	CCONJ
aji-171	305	30	biological	biological	ADJ
aji-171	305	31	outcomes	outcome	NOUN
aji-171	305	32	(	(	PUNCT
aji-171	305	33	sun	sun	NOUN
aji-171	305	34	et	et	PROPN
aji-171	305	35	al	al	PROPN
aji-171	305	36	.	.	PROPN
aji-171	305	37	,	,	PUNCT
aji-171	305	38	2023	2023	NUM
aji-171	305	39	)	)	PUNCT
aji-171	305	40	have	have	AUX
aji-171	305	41	been	be	AUX
aji-171	305	42	studied	study	VERB
aji-171	305	43	and	and	CCONJ
aji-171	305	44	identified	identify	VERB
aji-171	305	45	in	in	ADP
aji-171	305	46	individuals	individual	NOUN
aji-171	305	47	and	and	CCONJ
aji-171	305	48	populations	population	NOUN
aji-171	305	49	through	through	ADP
aji-171	305	50	metabolomics	metabolomic	NOUN
aji-171	305	51	fingerprinting	fingerprinting	NOUN
aji-171	305	52	and	and	CCONJ
aji-171	305	53	footprinting	footprinte	VERB
aji-171	305	54	techniques	technique	NOUN
aji-171	305	55	,	,	PUNCT
aji-171	305	56	which	which	PRON
aji-171	305	57	will	will	AUX
aji-171	305	58	facilitate	facilitate	VERB
aji-171	305	59	precision	precision	NOUN
aji-171	305	60	medicine	medicine	NOUN
aji-171	305	61	and	and	CCONJ
aji-171	305	62	public	public	ADJ
aji-171	305	63	healthcare	healthcare	NOUN
aji-171	305	64	(	(	PUNCT
aji-171	305	65	guo	guo	PROPN
aji-171	305	66	et	et	PROPN
aji-171	305	67	al	al	PROPN
aji-171	305	68	.	.	PROPN
aji-171	305	69	,	,	PUNCT
aji-171	305	70	2023	2023	NUM
aji-171	305	71	;	;	PUNCT
aji-171	305	72	wang	wang	PROPN
aji-171	305	73	et	et	PROPN
aji-171	305	74	al	al	PROPN
aji-171	305	75	.	.	PROPN
aji-171	305	76	,	,	PUNCT
aji-171	305	77	2023	2023	NUM
aji-171	305	78	;	;	PUNCT
aji-171	305	79	xu	xu	PROPN
aji-171	305	80	et	et	PROPN
aji-171	305	81	al	al	PROPN
aji-171	305	82	.	.	PROPN
aji-171	305	83	,	,	PUNCT
aji-171	305	84	2023	2023	NUM
aji-171	305	85	;	;	PUNCT
aji-171	305	86	ou	ou	PROPN
aji-171	305	87	et	et	PROPN
aji-171	305	88	al	al	PROPN
aji-171	305	89	.	.	PROPN
aji-171	305	90	,	,	PUNCT
aji-171	305	91	2024	2024	NUM
aji-171	305	92	;	;	PUNCT
aji-171	305	93	zhou	zhou	PROPN
aji-171	305	94	et	et	PROPN
aji-171	305	95	al	al	PROPN
aji-171	305	96	.	.	PROPN
aji-171	305	97	,	,	PUNCT
aji-171	305	98	2024	2024	NUM
aji-171	305	99	;	;	PUNCT
aji-171	305	100	xu	xu	PROPN
aji-171	305	101	,	,	PUNCT
aji-171	305	102	et	et	PROPN
aji-171	305	103	,	,	PUNCT
aji-171	305	104	al	al	PROPN
aji-171	305	105	.	.	PROPN
aji-171	305	106	,	,	PUNCT
aji-171	305	107	2024	2024	NUM
aji-171	305	108	)	)	PUNCT
aji-171	305	109	.	.	PUNCT
aji-171	306	1	the	the	DET
aji-171	306	2	transition	transition	NOUN
aji-171	306	3	from	from	ADP
aji-171	306	4	genome	genome	NOUN
aji-171	306	5	-	-	PUNCT
aji-171	306	6	wide	wide	ADJ
aji-171	306	7	association	association	NOUN
aji-171	306	8	studies	study	NOUN
aji-171	306	9	(	(	PUNCT
aji-171	306	10	gwas	gwas	PROPN
aji-171	306	11	)	)	PUNCT
aji-171	306	12	to	to	PART
aji-171	306	13	metabolome	metabolome	VERB
aji-171	306	14	-	-	PUNCT
aji-171	306	15	wide	wide	ADJ
aji-171	306	16	association	association	NOUN
aji-171	306	17	studies	study	NOUN
aji-171	306	18	(	(	PUNCT
aji-171	306	19	mwas	mwas	NOUN
aji-171	306	20	)	)	PUNCT
aji-171	306	21	was	be	AUX
aji-171	306	22	initially	initially	ADV
aji-171	306	23	defined	define	VERB
aji-171	306	24	in	in	ADP
aji-171	306	25	2008	2008	NUM
aji-171	306	26	as	as	ADP
aji-171	306	27	"	"	PUNCT
aji-171	306	28	an	an	DET
aji-171	306	29	investigation	investigation	NOUN
aji-171	306	30	of	of	ADP
aji-171	306	31	the	the	DET
aji-171	306	32	relationships	relationship	NOUN
aji-171	306	33	between	between	ADP
aji-171	306	34	phenotype	phenotype	NOUN
aji-171	306	35	variation	variation	NOUN
aji-171	306	36	and	and	CCONJ
aji-171	306	37	disease	disease	NOUN
aji-171	306	38	risk	risk	NOUN
aji-171	306	39	factors	factor	NOUN
aji-171	306	40	through	through	ADP
aji-171	306	41	environmental	environmental	ADJ
aji-171	306	42	and	and	CCONJ
aji-171	306	43	genomic	genomic	NOUN
aji-171	306	44	influences	influence	NOUN
aji-171	306	45	"	"	PUNCT
aji-171	306	46	(	(	PUNCT
aji-171	306	47	xu	xu	INTJ
aji-171	306	48	et	et	PROPN
aji-171	306	49	al	al	PROPN
aji-171	306	50	.	.	PROPN
aji-171	306	51	,	,	PUNCT
aji-171	306	52	2023	2023	NUM
aji-171	306	53	;	;	PUNCT
aji-171	306	54	ou	ou	PROPN
aji-171	306	55	et	et	PROPN
aji-171	306	56	al	al	PROPN
aji-171	306	57	.	.	PROPN
aji-171	306	58	,	,	PUNCT
aji-171	306	59	2024	2024	NUM
aji-171	306	60	)	)	PUNCT
aji-171	306	61	.	.	PUNCT
aji-171	307	1	exposures	exposure	NOUN
aji-171	307	2	to	to	ADP
aji-171	307	3	single	single	ADJ
aji-171	307	4	individual	individual	ADJ
aji-171	307	5	phenotypes	phenotype	NOUN
aji-171	307	6	and	and	CCONJ
aji-171	307	7	populations	population	NOUN
aji-171	307	8	,	,	PUNCT
aji-171	307	9	epidemiologic	epidemiologic	ADJ
aji-171	307	10	research	research	NOUN
aji-171	307	11	,	,	PUNCT
aji-171	307	12	disease	disease	NOUN
aji-171	307	13	risk	risk	NOUN
aji-171	307	14	,	,	PUNCT
aji-171	307	15	metabolome	metabolome	NOUN
aji-171	307	16	-	-	PUNCT
aji-171	307	17	wide	wide	ADJ
aji-171	307	18	association	association	NOUN
aji-171	307	19	studies	study	NOUN
aji-171	307	20	,	,	PUNCT
aji-171	307	21	and	and	CCONJ
aji-171	307	22	precision	precision	NOUN
aji-171	307	23	medicine	medicine	NOUN
aji-171	307	24	were	be	AUX
aji-171	307	25	proposed	propose	VERB
aji-171	307	26	by	by	ADP
aji-171	307	27	rattray	rattray	PROPN
aji-171	307	28	and	and	CCONJ
aji-171	307	29	colleagues	colleague	NOUN
aji-171	307	30	(	(	PUNCT
aji-171	307	31	ou	ou	X
aji-171	307	32	et	et	PROPN
aji-171	307	33	al	al	PROPN
aji-171	307	34	.	.	PROPN
aji-171	307	35	,	,	PUNCT
aji-171	307	36	2024	2024	NUM
aji-171	307	37	)	)	PUNCT
aji-171	307	38	.	.	PUNCT
aji-171	308	1	6	6	X
aji-171	308	2	.	.	X
aji-171	308	3	metabolomics	metabolomic	NOUN
aji-171	308	4	and	and	CCONJ
aji-171	308	5	the	the	DET
aji-171	308	6	exposome	exposome	NOUN
aji-171	308	7	unique	unique	ADJ
aji-171	308	8	opportunities	opportunity	NOUN
aji-171	308	9	to	to	PART
aji-171	308	10	identify	identify	VERB
aji-171	308	11	food	food	NOUN
aji-171	308	12	ingredients	ingredient	NOUN
aji-171	308	13	and	and	CCONJ
aji-171	308	14	comprehend	comprehend	VERB
aji-171	308	15	their	their	PRON
aji-171	308	16	role	role	NOUN
aji-171	308	17	in	in	ADP
aji-171	308	18	the	the	DET
aji-171	308	19	dietary	dietary	ADJ
aji-171	308	20	exposome	exposome	NOUN
aji-171	308	21	and	and	CCONJ
aji-171	308	22	food	food	NOUN
aji-171	308	23	quality	quality	NOUN
aji-171	308	24	are	be	AUX
aji-171	308	25	provided	provide	VERB
aji-171	308	26	by	by	ADP
aji-171	308	27	metabolomics	metabolomic	NOUN
aji-171	308	28	.	.	PUNCT
aji-171	309	1	modern	modern	ADJ
aji-171	309	2	metabolomics	metabolomic	NOUN
aji-171	309	3	techniques	technique	NOUN
aji-171	309	4	were	be	AUX
aji-171	309	5	employed	employ	VERB
aji-171	309	6	in	in	ADP
aji-171	309	7	a	a	DET
aji-171	309	8	study	study	NOUN
aji-171	309	9	by	by	ADP
aji-171	309	10	nikou	nikou	PROPN
aji-171	309	11	et	et	PROPN
aji-171	309	12	al	al	PROPN
aji-171	309	13	.	.	PROPN
aji-171	310	1	(	(	PUNCT
aji-171	310	2	2020	2020	NUM
aji-171	310	3	)	)	PUNCT
aji-171	311	1	to	to	PART
aji-171	311	2	find	find	VERB
aji-171	311	3	chemical	chemical	ADJ
aji-171	311	4	biomarkers	biomarker	NOUN
aji-171	311	5	relevant	relevant	ADJ
aji-171	311	6	to	to	ADP
aji-171	311	7	the	the	DET
aji-171	311	8	production	production	NOUN
aji-171	311	9	process	process	NOUN
aji-171	311	10	,	,	PUNCT
aji-171	311	11	cultivation	cultivation	NOUN
aji-171	311	12	methods	method	NOUN
aji-171	311	13	,	,	PUNCT
aji-171	311	14	and	and	CCONJ
aji-171	311	15	geographic	geographic	ADJ
aji-171	311	16	origin	origin	NOUN
aji-171	311	17	of	of	ADP
aji-171	311	18	olive	olive	NOUN
aji-171	311	19	oil	oil	NOUN
aji-171	311	20	,	,	PUNCT
aji-171	311	21	a	a	DET
aji-171	311	22	component	component	NOUN
aji-171	311	23	of	of	ADP
aji-171	311	24	the	the	DET
aji-171	311	25	mediterranean	mediterranean	PROPN
aji-171	311	26	diet	diet	NOUN
aji-171	311	27	that	that	PRON
aji-171	311	28	has	have	AUX
aji-171	311	29	been	be	AUX
aji-171	311	30	described	describe	VERB
aji-171	311	31	as	as	ADP
aji-171	311	32	a	a	DET
aji-171	311	33	nutritious	nutritious	ADJ
aji-171	311	34	dietary	dietary	ADJ
aji-171	311	35	pattern	pattern	NOUN
aji-171	311	36	.	.	PUNCT
aji-171	312	1	to	to	PART
aji-171	312	2	examine	examine	VERB
aji-171	312	3	intact	intact	ADJ
aji-171	312	4	oil	oil	NOUN
aji-171	312	5	and	and	CCONJ
aji-171	312	6	the	the	DET
aji-171	312	7	associated	associated	ADJ
aji-171	312	8	polyphenols	polyphenol	NOUN
aji-171	312	9	of	of	ADP
aji-171	312	10	extra	extra	ADJ
aji-171	312	11	virgin	virgin	ADJ
aji-171	312	12	olive	olive	NOUN
aji-171	312	13	oils	oil	NOUN
aji-171	312	14	,	,	PUNCT
aji-171	312	15	metabolomic	metabolomic	ADJ
aji-171	312	16	profiling	profiling	NOUN
aji-171	312	17	using	use	VERB
aji-171	312	18	flow	flow	NOUN
aji-171	312	19	injection	injection	NOUN
aji-171	312	20	analysis	analysis	NOUN
aji-171	312	21	-	-	PUNCT
aji-171	312	22	magnetical	magnetical	ADJ
aji-171	312	23	resonance	resonance	NOUN
aji-171	312	24	mass	mass	NOUN
aji-171	312	25	spectrometry	spectrometry	NOUN
aji-171	312	26	(	(	PUNCT
aji-171	312	27	fia	fia	NOUN
aji-171	312	28	-	-	PUNCT
aji-171	312	29	mrms	mrm	NOUN
aji-171	312	30	)	)	PUNCT
aji-171	312	31	and	and	CCONJ
aji-171	312	32	the	the	DET
aji-171	312	33	lc	lc	NOUN
aji-171	312	34	-	-	PUNCT
aji-171	312	35	orbitrap	orbitrap	NOUN
aji-171	312	36	ms	ms	NOUN
aji-171	312	37	platform	platform	NOUN
aji-171	312	38	was	be	AUX
aji-171	312	39	employed	employ	VERB
aji-171	312	40	.	.	PUNCT
aji-171	313	1	the	the	DET
aji-171	313	2	approach	approach	NOUN
aji-171	313	3	may	may	AUX
aji-171	313	4	provide	provide	VERB
aji-171	313	5	a	a	DET
aji-171	313	6	means	means	NOUN
aji-171	313	7	of	of	ADP
aji-171	313	8	combating	combat	VERB
aji-171	313	9	food	food	NOUN
aji-171	313	10	fraud	fraud	NOUN
aji-171	313	11	and	and	CCONJ
aji-171	313	12	adulteration	adulteration	NOUN
aji-171	313	13	while	while	SCONJ
aji-171	313	14	also	also	ADV
aji-171	313	15	identifying	identify	VERB
aji-171	313	16	elements	element	NOUN
aji-171	313	17	of	of	ADP
aji-171	313	18	a	a	DET
aji-171	313	19	nutritious	nutritious	ADJ
aji-171	313	20	diet	diet	NOUN
aji-171	313	21	.	.	PUNCT
aji-171	314	1	occupational	occupational	ADJ
aji-171	314	2	exposures	exposure	NOUN
aji-171	314	3	and	and	CCONJ
aji-171	314	4	patterns	pattern	NOUN
aji-171	314	5	,	,	PUNCT
aji-171	314	6	such	such	ADJ
aji-171	314	7	as	as	ADP
aji-171	314	8	shift	shift	NOUN
aji-171	314	9	work	work	NOUN
aji-171	314	10	,	,	PUNCT
aji-171	314	11	are	be	AUX
aji-171	314	12	a	a	DET
aji-171	314	13	significant	significant	ADJ
aji-171	314	14	component	component	NOUN
aji-171	314	15	of	of	ADP
aji-171	314	16	the	the	DET
aji-171	314	17	exposome	exposome	NOUN
aji-171	314	18	.	.	PUNCT
aji-171	315	1	in	in	ADP
aji-171	315	2	recent	recent	ADJ
aji-171	315	3	years	year	NOUN
aji-171	315	4	,	,	PUNCT
aji-171	315	5	shift	shift	NOUN
aji-171	315	6	work	work	NOUN
aji-171	315	7	has	have	AUX
aji-171	315	8	been	be	AUX
aji-171	315	9	linked	link	VERB
aji-171	315	10	to	to	ADP
aji-171	315	11	a	a	DET
aji-171	315	12	number	number	NOUN
aji-171	315	13	of	of	ADP
aji-171	315	14	physiological	physiological	ADJ
aji-171	315	15	changes	change	NOUN
aji-171	315	16	and	and	CCONJ
aji-171	315	17	may	may	AUX
aji-171	315	18	be	be	AUX
aji-171	315	19	related	relate	VERB
aji-171	315	20	to	to	ADP
aji-171	315	21	a	a	DET
aji-171	315	22	number	number	NOUN
aji-171	315	23	of	of	ADP
aji-171	315	24	diseases	disease	NOUN
aji-171	315	25	.	.	PUNCT
aji-171	316	1	report	report	NOUN
aji-171	316	2	by	by	ADP
aji-171	316	3	borroni	borroni	PROPN
aji-171	316	4	et	et	PROPN
aji-171	316	5	al	al	PROPN
aji-171	316	6	.	.	PROPN
aji-171	317	1	(	(	PUNCT
aji-171	317	2	2023	2023	NUM
aji-171	317	3	)	)	PUNCT
aji-171	317	4	assessed	assess	VERB
aji-171	317	5	how	how	SCONJ
aji-171	317	6	night	night	NOUN
aji-171	317	7	shift	shift	NOUN
aji-171	317	8	work	work	NOUN
aji-171	317	9	affected	affect	VERB
aji-171	317	10	the	the	DET
aji-171	317	11	serum	serum	NOUN
aji-171	317	12	metabolome	metabolome	NOUN
aji-171	317	13	in	in	ADP
aji-171	317	14	a	a	DET
aji-171	317	15	group	group	NOUN
aji-171	317	16	of	of	ADP
aji-171	317	17	italian	italian	ADJ
aji-171	317	18	female	female	ADJ
aji-171	317	19	nurses	nurse	NOUN
aji-171	317	20	who	who	PRON
aji-171	317	21	worked	work	VERB
aji-171	317	22	nights	night	NOUN
aji-171	317	23	and	and	CCONJ
aji-171	317	24	female	female	ADJ
aji-171	317	25	coworkers	coworker	NOUN
aji-171	317	26	who	who	PRON
aji-171	317	27	did	do	VERB
aji-171	317	28	not	not	PART
aji-171	317	29	.	.	PUNCT
aji-171	318	1	they	they	PRON
aji-171	318	2	found	find	VERB
aji-171	318	3	that	that	SCONJ
aji-171	318	4	there	there	PRON
aji-171	318	5	were	be	VERB
aji-171	318	6	variations	variation	NOUN
aji-171	318	7	in	in	ADP
aji-171	318	8	the	the	DET
aji-171	318	9	levels	level	NOUN
aji-171	318	10	of	of	ADP
aji-171	318	11	taurine	taurine	NOUN
aji-171	318	12	,	,	PUNCT
aji-171	318	13	serotonin	serotonin	VERB
aji-171	318	14	,	,	PUNCT
aji-171	318	15	aspartic	aspartic	ADJ
aji-171	318	16	acid	acid	NOUN
aji-171	318	17	,	,	PUNCT
aji-171	318	18	and	and	CCONJ
aji-171	318	19	certain	certain	ADJ
aji-171	318	20	lipids	lipid	NOUN
aji-171	318	21	,	,	PUNCT
aji-171	318	22	all	all	PRON
aji-171	318	23	of	of	ADP
aji-171	318	24	which	which	PRON
aji-171	318	25	provide	provide	VERB
aji-171	318	26	hints	hint	NOUN
aji-171	318	27	about	about	ADP
aji-171	318	28	the	the	DET
aji-171	318	29	biological	biological	ADJ
aji-171	318	30	changes	change	NOUN
aji-171	318	31	brought	bring	VERB
aji-171	318	32	on	on	ADP
aji-171	318	33	by	by	ADP
aji-171	318	34	working	working	ADJ
aji-171	318	35	nights	night	NOUN
aji-171	318	36	.	.	PUNCT
aji-171	319	1	according	accord	VERB
aji-171	319	2	to	to	ADP
aji-171	319	3	barupal	barupal	PROPN
aji-171	319	4	et	et	PROPN
aji-171	319	5	al	al	PROPN
aji-171	319	6	.	.	PROPN
aji-171	320	1	(	(	PUNCT
aji-171	320	2	2022	2022	NUM
aji-171	320	3	)	)	PUNCT
aji-171	320	4	reprocessing	reprocess	VERB
aji-171	320	5	metabolomics	metabolomic	NOUN
aji-171	320	6	datasets	dataset	NOUN
aji-171	320	7	that	that	PRON
aji-171	320	8	have	have	AUX
aji-171	320	9	already	already	ADV
aji-171	320	10	been	be	AUX
aji-171	320	11	published	publish	VERB
aji-171	320	12	and	and	CCONJ
aji-171	320	13	made	make	VERB
aji-171	320	14	publicly	publicly	ADV
aji-171	320	15	available	available	ADJ
aji-171	320	16	can	can	AUX
aji-171	320	17	alter	alter	VERB
aji-171	320	18	the	the	DET
aji-171	320	19	number	number	NOUN
aji-171	320	20	of	of	ADP
aji-171	320	21	metabolite	metabolite	NOUN
aji-171	320	22	identifications	identification	NOUN
aji-171	320	23	made	make	VERB
aji-171	320	24	and	and	CCONJ
aji-171	320	25	possibly	possibly	ADV
aji-171	320	26	reveal	reveal	VERB
aji-171	320	27	new	new	ADJ
aji-171	320	28	biomarkers	biomarker	NOUN
aji-171	320	29	that	that	PRON
aji-171	320	30	were	be	AUX
aji-171	320	31	overlooked	overlook	VERB
aji-171	320	32	during	during	ADP
aji-171	320	33	the	the	DET
aji-171	320	34	initial	initial	ADJ
aji-171	320	35	processing	processing	NOUN
aji-171	320	36	,	,	PUNCT
aji-171	320	37	as	as	ADP
aji-171	320	38	the	the	DET
aji-171	320	39	authors	author	NOUN
aji-171	320	40	of	of	ADP
aji-171	320	41	the	the	DET
aji-171	320	42	paper	paper	NOUN
aji-171	320	43	by	by	ADP
aji-171	320	44	barupal	barupal	PROPN
aji-171	320	45	et	et	PROPN
aji-171	320	46	al	al	PROPN
aji-171	320	47	.	.	PROPN
aji-171	321	1	(	(	PUNCT
aji-171	321	2	2022	2022	NUM
aji-171	321	3	)	)	PUNCT
aji-171	321	4	showed	show	VERB
aji-171	321	5	.	.	PUNCT
aji-171	322	1	in	in	ADP
aji-171	322	2	contrast	contrast	NOUN
aji-171	322	3	to	to	ADP
aji-171	322	4	the	the	DET
aji-171	322	5	initial	initial	ADJ
aji-171	322	6	data	datum	NOUN
aji-171	322	7	preprocessing	preprocessing	NOUN
aji-171	322	8	method	method	NOUN
aji-171	322	9	that	that	PRON
aji-171	322	10	employed	employ	VERB
aji-171	322	11	the	the	DET
aji-171	322	12	mass	mass	ADJ
aji-171	322	13	spectrometer	spectrometer	NOUN
aji-171	322	14	manufacturer	manufacturer	NOUN
aji-171	322	15	's	's	PART
aji-171	322	16	software	software	NOUN
aji-171	322	17	,	,	PUNCT
aji-171	322	18	the	the	DET
aji-171	322	19	authors	author	NOUN
aji-171	322	20	used	use	VERB
aji-171	322	21	ms	ms	NOUN
aji-171	322	22	-	-	PUNCT
aji-171	322	23	dial	dial	NOUN
aji-171	322	24	,	,	PUNCT
aji-171	322	25	a	a	DET
aji-171	322	26	publicly	publicly	ADV
aji-171	322	27	available	available	ADJ
aji-171	322	28	program	program	NOUN
aji-171	322	29	,	,	PUNCT
aji-171	322	30	for	for	ADP
aji-171	322	31	data	datum	NOUN
aji-171	322	32	pre	pre	ADJ
aji-171	322	33	-	-	ADJ
aji-171	322	34	processing	process	VERB
aji-171	322	35	and	and	CCONJ
aji-171	322	36	applied	apply	VERB
aji-171	322	37	less	less	ADV
aji-171	322	38	strict	strict	ADJ
aji-171	322	39	data	datum	NOUN
aji-171	322	40	processing	processing	NOUN
aji-171	322	41	thresholds	threshold	NOUN
aji-171	322	42	.	.	PUNCT
aji-171	323	1	different	different	ADJ
aji-171	323	2	software	software	NOUN
aji-171	323	3	and	and	CCONJ
aji-171	323	4	even	even	ADV
aji-171	323	5	small	small	ADJ
aji-171	323	6	adjustments	adjustment	NOUN
aji-171	323	7	to	to	ADP
aji-171	323	8	preprocessing	preprocesse	VERB
aji-171	323	9	parameters	parameter	NOUN
aji-171	323	10	can	can	AUX
aji-171	323	11	affect	affect	VERB
aji-171	323	12	the	the	DET
aji-171	323	13	quality	quality	NOUN
aji-171	323	14	and	and	CCONJ
aji-171	323	15	quantity	quantity	NOUN
aji-171	323	16	of	of	ADP
aji-171	323	17	data	datum	NOUN
aji-171	323	18	reported	report	VERB
aji-171	323	19	,	,	PUNCT
aji-171	323	20	as	as	SCONJ
aji-171	323	21	the	the	DET
aji-171	323	22	manuscript	manuscript	NOUN
aji-171	323	23	illustrated	illustrate	VERB
aji-171	323	24	.	.	PUNCT
aji-171	324	1	this	this	PRON
aji-171	324	2	presents	present	VERB
aji-171	324	3	both	both	DET
aji-171	324	4	opportunities	opportunity	NOUN
aji-171	324	5	and	and	CCONJ
aji-171	324	6	challenges	challenge	NOUN
aji-171	324	7	.	.	PUNCT
aji-171	325	1	keski	keski	PROPN
aji-171	325	2	-	-	PUNCT
aji-171	325	3	rahkonen	rahkonen	PROPN
aji-171	325	4	et	et	PROPN
aji-171	325	5	al	al	PROPN
aji-171	325	6	.	.	PROPN
aji-171	326	1	(	(	PUNCT
aji-171	326	2	2021	2021	NUM
aji-171	326	3	)	)	PUNCT
aji-171	326	4	and	and	CCONJ
aji-171	326	5	barupal	barupal	NOUN
aji-171	326	6	et	et	PROPN
aji-171	326	7	al	al	PROPN
aji-171	326	8	.	.	PROPN
aji-171	327	1	(	(	PUNCT
aji-171	327	2	2022	2022	NUM
aji-171	327	3	)	)	PUNCT
aji-171	327	4	two	two	NUM
aji-171	327	5	additional	additional	ADJ
aji-171	327	6	comments	comment	NOUN
aji-171	327	7	on	on	ADP
aji-171	327	8	the	the	DET
aji-171	327	9	manuscript	manuscript	NOUN
aji-171	327	10	sparked	spark	VERB
aji-171	327	11	a	a	DET
aji-171	327	12	heated	heated	ADJ
aji-171	327	13	discussion	discussion	NOUN
aji-171	327	14	that	that	PRON
aji-171	327	15	added	add	VERB
aji-171	327	16	to	to	ADP
aji-171	327	17	the	the	DET
aji-171	327	18	metabolomics	metabolomic	NOUN
aji-171	327	19	community	community	NOUN
aji-171	327	20	's	's	PART
aji-171	327	21	broader	broad	ADJ
aji-171	327	22	conversations	conversation	NOUN
aji-171	327	23	regarding	regard	VERB
aji-171	327	24	data	datum	NOUN
aji-171	327	25	pre	pre	ADJ
aji-171	327	26	-	-	ADJ
aji-171	327	27	processing	processing	ADJ
aji-171	327	28	techniques	technique	NOUN
aji-171	327	29	,	,	PUNCT
aji-171	327	30	software	software	NOUN
aji-171	327	31	and	and	CCONJ
aji-171	327	32	parameters	parameter	NOUN
aji-171	327	33	,	,	PUNCT
aji-171	327	34	reporting	reporting	NOUN
aji-171	327	35	standards	standard	NOUN
aji-171	327	36	and	and	CCONJ
aji-171	327	37	formats	format	NOUN
aji-171	327	38	,	,	PUNCT
aji-171	327	39	and	and	CCONJ
aji-171	327	40	intercomparability	intercomparability	NOUN
aji-171	327	41	among	among	ADP
aji-171	327	42	data	datum	NOUN
aji-171	327	43	pre	pre	ADJ
aji-171	327	44	-	-	ADJ
aji-171	327	45	processing	processing	ADJ
aji-171	327	46	methods	method	NOUN
aji-171	327	47	.	.	PUNCT
aji-171	328	1	7	7	X
aji-171	328	2	.	.	X
aji-171	328	3	future	future	ADJ
aji-171	328	4	direction	direction	NOUN
aji-171	328	5	of	of	ADP
aji-171	328	6	metabolomics	metabolomic	NOUN
aji-171	328	7	metabolomics	metabolomic	NOUN
aji-171	328	8	technology	technology	NOUN
aji-171	328	9	will	will	AUX
aji-171	328	10	be	be	AUX
aji-171	328	11	integrated	integrate	VERB
aji-171	328	12	with	with	ADP
aji-171	328	13	other	other	ADJ
aji-171	328	14	cutting	cutting	NOUN
aji-171	328	15	-	-	PUNCT
aji-171	328	16	edge	edge	NOUN
aji-171	328	17	technologies	technology	NOUN
aji-171	328	18	to	to	PART
aji-171	328	19	guarantee	guarantee	VERB
aji-171	328	20	its	its	PRON
aji-171	328	21	expansion	expansion	NOUN
aji-171	328	22	.	.	PUNCT
aji-171	329	1	ms	ms	PROPN
aji-171	329	2	-	-	PUNCT
aji-171	329	3	based	base	VERB
aji-171	329	4	metabolomics	metabolomic	NOUN
aji-171	329	5	will	will	AUX
aji-171	329	6	be	be	AUX
aji-171	329	7	more	more	ADV
aji-171	329	8	precise	precise	ADJ
aji-171	329	9	,	,	PUNCT
aji-171	329	10	and	and	CCONJ
aji-171	329	11	a	a	DET
aji-171	329	12	number	number	NOUN
aji-171	329	13	of	of	ADP
aji-171	329	14	combined	combined	ADJ
aji-171	329	15	techniques	technique	NOUN
aji-171	329	16	,	,	PUNCT
aji-171	329	17	including	include	VERB
aji-171	329	18	gc	gc	PROPN
aji-171	329	19	/	/	SYM
aji-171	329	20	ms	ms	PROPN
aji-171	329	21	,	,	PUNCT
aji-171	329	22	lc	lc	PROPN
aji-171	329	23	/	/	SYM
aji-171	329	24	ms	ms	PROPN
aji-171	329	25	,	,	PUNCT
aji-171	329	26	and	and	CCONJ
aji-171	329	27	others	other	NOUN
aji-171	329	28	,	,	PUNCT
aji-171	329	29	will	will	AUX
aji-171	329	30	provide	provide	VERB
aji-171	329	31	a	a	DET
aji-171	329	32	strong	strong	ADJ
aji-171	329	33	scientific	scientific	ADJ
aji-171	329	34	basis	basis	NOUN
aji-171	329	35	for	for	ADP
aji-171	329	36	tackling	tackle	VERB
aji-171	329	37	the	the	DET
aji-171	329	38	challenge	challenge	NOUN
aji-171	329	39	of	of	ADP
aji-171	329	40	metabolite	metabolite	NOUN
aji-171	329	41	analysis	analysis	NOUN
aji-171	329	42	and	and	CCONJ
aji-171	329	43	metabolic	metabolic	NOUN
aji-171	329	44	pathway	pathway	NOUN
aji-171	329	45	discovery	discovery	NOUN
aji-171	329	46	.	.	PUNCT
aji-171	330	1	extended	extend	VERB
aji-171	330	2	mass	mass	NOUN
aji-171	330	3	spectrometry	spectrometry	NOUN
aji-171	330	4	holds	hold	VERB
aji-171	330	5	a	a	DET
aji-171	330	6	prominent	prominent	ADJ
aji-171	330	7	position	position	NOUN
aji-171	330	8	as	as	ADP
aji-171	330	9	a	a	DET
aji-171	330	10	vital	vital	ADJ
aji-171	330	11	analytical	analytical	ADJ
aji-171	330	12	tool	tool	NOUN
aji-171	330	13	in	in	ADP
aji-171	330	14	the	the	DET
aji-171	330	15	field	field	NOUN
aji-171	330	16	of	of	ADP
aji-171	330	17	metabolomics	metabolomic	NOUN
aji-171	330	18	.	.	PUNCT
aji-171	331	1	the	the	DET
aji-171	331	2	growth	growth	NOUN
aji-171	331	3	of	of	ADP
aji-171	331	4	this	this	DET
aji-171	331	5	field	field	NOUN
aji-171	331	6	has	have	AUX
aji-171	331	7	provided	provide	VERB
aji-171	331	8	insight	insight	NOUN
aji-171	331	9	into	into	ADP
aji-171	331	10	the	the	DET
aji-171	331	11	etiology	etiology	NOUN
aji-171	331	12	of	of	ADP
aji-171	331	13	many	many	ADJ
aji-171	331	14	diseases	disease	NOUN
aji-171	331	15	and	and	CCONJ
aji-171	331	16	assisted	assist	VERB
aji-171	331	17	in	in	ADP
aji-171	331	18	the	the	DET
aji-171	331	19	identification	identification	NOUN
aji-171	331	20	of	of	ADP
aji-171	331	21	numerous	numerous	ADJ
aji-171	331	22	potential	potential	ADJ
aji-171	331	23	illness	illness	NOUN
aji-171	331	24	biomarkers	biomarker	NOUN
aji-171	331	25	(	(	PUNCT
aji-171	331	26	xiong	xiong	PROPN
aji-171	331	27	et	et	PROPN
aji-171	331	28	al	al	PROPN
aji-171	331	29	.	.	PROPN
aji-171	331	30	,	,	PUNCT
aji-171	331	31	2020	2020	NUM
aji-171	331	32	)	)	PUNCT
aji-171	331	33	.	.	PUNCT
aji-171	332	1	mamman	mamman	NOUN
aji-171	332	2	et	et	PROPN
aji-171	332	3	al	al	PROPN
aji-171	332	4	.	.	PROPN
aji-171	332	5	;	;	PUNCT
aji-171	332	6	asian	asian	PROPN
aji-171	332	7	j.	j.	PROPN
aji-171	332	8	immunol	immunol	PROPN
aji-171	332	9	.	.	PROPN
aji-171	332	10	,	,	PUNCT
aji-171	332	11	vol	vol	NOUN
aji-171	332	12	.	.	PROPN
aji-171	332	13	8	8	NUM
aji-171	332	14	,	,	PUNCT
aji-171	332	15	no	no	INTJ
aji-171	332	16	.	.	NOUN
aji-171	332	17	1	1	NUM
aji-171	332	18	,	,	PUNCT
aji-171	332	19	pp	pp	ADJ
aji-171	332	20	.	.	PUNCT
aji-171	333	1	190	190	NUM
aji-171	333	2	-	-	SYM
aji-171	333	3	206	206	NUM
aji-171	333	4	,	,	PUNCT
aji-171	333	5	2025	2025	NUM
aji-171	333	6	;	;	PUNCT
aji-171	333	7	article	article	NOUN
aji-171	333	8	no.aji.140476	no.aji.140476	ADV
aji-171	333	9	200	200	NUM
aji-171	333	10	some	some	PRON
aji-171	333	11	of	of	ADP
aji-171	333	12	the	the	DET
aji-171	333	13	studies	study	NOUN
aji-171	333	14	that	that	PRON
aji-171	333	15	have	have	AUX
aji-171	333	16	been	be	AUX
aji-171	333	17	assessed	assess	VERB
aji-171	333	18	include	include	VERB
aji-171	333	19	research	research	NOUN
aji-171	333	20	for	for	ADP
aji-171	333	21	recurrence	recurrence	NOUN
aji-171	333	22	testing	testing	NOUN
aji-171	333	23	,	,	PUNCT
aji-171	333	24	appropriate	appropriate	ADJ
aji-171	333	25	treatment	treatment	NOUN
aji-171	333	26	,	,	PUNCT
aji-171	333	27	medication	medication	NOUN
aji-171	333	28	prognosis	prognosis	NOUN
aji-171	333	29	and	and	CCONJ
aji-171	333	30	prediction	prediction	NOUN
aji-171	333	31	,	,	PUNCT
aji-171	333	32	and	and	CCONJ
aji-171	333	33	early	early	ADJ
aji-171	333	34	disease	disease	NOUN
aji-171	333	35	diagnosis	diagnosis	NOUN
aji-171	333	36	(	(	PUNCT
aji-171	333	37	sun	sun	NOUN
aji-171	333	38	et	et	PROPN
aji-171	333	39	al	al	PROPN
aji-171	333	40	.	.	PROPN
aji-171	333	41	,	,	PUNCT
aji-171	333	42	2019	2019	NUM
aji-171	333	43	)	)	PUNCT
aji-171	333	44	.	.	PUNCT
aji-171	334	1	lc	lc	PROPN
aji-171	334	2	,	,	PUNCT
aji-171	334	3	gc	gc	PROPN
aji-171	334	4	,	,	PUNCT
aji-171	334	5	or	or	CCONJ
aji-171	334	6	ce	ce	PROPN
aji-171	334	7	is	be	AUX
aji-171	334	8	used	use	VERB
aji-171	334	9	in	in	ADP
aji-171	334	10	most	most	ADJ
aji-171	334	11	ms	ms	ADJ
aji-171	334	12	analytical	analytical	ADJ
aji-171	334	13	procedures	procedure	NOUN
aji-171	334	14	because	because	SCONJ
aji-171	334	15	biological	biological	ADJ
aji-171	334	16	mixtures	mixture	NOUN
aji-171	334	17	are	be	AUX
aji-171	334	18	very	very	ADV
aji-171	334	19	complex	complex	ADJ
aji-171	334	20	.	.	PUNCT
aji-171	335	1	rapidly	rapidly	ADV
aji-171	335	2	growing	grow	VERB
aji-171	335	3	applications	application	NOUN
aji-171	335	4	using	use	VERB
aji-171	335	5	evolving	evolve	VERB
aji-171	335	6	separation	separation	NOUN
aji-171	335	7	mechanisms	mechanism	NOUN
aji-171	335	8	and	and	CCONJ
aji-171	335	9	protocols	protocol	NOUN
aji-171	335	10	do	do	AUX
aji-171	335	11	present	present	VERB
aji-171	335	12	both	both	DET
aji-171	335	13	opportunities	opportunity	NOUN
aji-171	335	14	and	and	CCONJ
aji-171	335	15	challenges	challenge	NOUN
aji-171	335	16	,	,	PUNCT
aji-171	335	17	though	though	ADV
aji-171	335	18	.	.	PUNCT
aji-171	336	1	with	with	ADP
aji-171	336	2	the	the	DET
aji-171	336	3	advent	advent	NOUN
aji-171	336	4	of	of	ADP
aji-171	336	5	chromatographic	chromatographic	ADJ
aji-171	336	6	techniques	technique	NOUN
aji-171	336	7	,	,	PUNCT
aji-171	336	8	the	the	DET
aji-171	336	9	capacity	capacity	NOUN
aji-171	336	10	to	to	PART
aji-171	336	11	separate	separate	VERB
aji-171	336	12	metabolites	metabolite	NOUN
aji-171	336	13	and	and	CCONJ
aji-171	336	14	enhance	enhance	VERB
aji-171	336	15	the	the	DET
aji-171	336	16	number	number	NOUN
aji-171	336	17	of	of	ADP
aji-171	336	18	metabolites	metabolite	NOUN
aji-171	336	19	identified	identify	VERB
aji-171	336	20	has	have	AUX
aji-171	336	21	surely	surely	ADV
aji-171	336	22	improved	improve	VERB
aji-171	336	23	(	(	PUNCT
aji-171	336	24	li	li	PROPN
aji-171	336	25	et	et	PROPN
aji-171	336	26	al	al	PROPN
aji-171	336	27	.	.	PROPN
aji-171	336	28	,	,	PUNCT
aji-171	336	29	2017	2017	NUM
aji-171	336	30	;	;	PUNCT
aji-171	336	31	zhang	zhang	PROPN
aji-171	336	32	et	et	PROPN
aji-171	336	33	al	al	PROPN
aji-171	336	34	.	.	PROPN
aji-171	336	35	,	,	PUNCT
aji-171	336	36	2019	2019	NUM
aji-171	336	37	)	)	PUNCT
aji-171	336	38	.	.	PUNCT
aji-171	337	1	the	the	DET
aji-171	337	2	inability	inability	NOUN
aji-171	337	3	to	to	PART
aji-171	337	4	analyze	analyze	VERB
aji-171	337	5	and	and	CCONJ
aji-171	337	6	relate	relate	VERB
aji-171	337	7	the	the	DET
aji-171	337	8	results	result	NOUN
aji-171	337	9	of	of	ADP
aji-171	337	10	the	the	DET
aji-171	337	11	latter	latter	ADJ
aji-171	337	12	studies	study	NOUN
aji-171	337	13	,	,	PUNCT
aji-171	337	14	which	which	PRON
aji-171	337	15	are	be	AUX
aji-171	337	16	carried	carry	VERB
aji-171	337	17	out	out	ADP
aji-171	337	18	on	on	ADP
aji-171	337	19	comparable	comparable	ADJ
aji-171	337	20	or	or	CCONJ
aji-171	337	21	identical	identical	ADJ
aji-171	337	22	samples	sample	NOUN
aji-171	337	23	gathered	gather	VERB
aji-171	337	24	by	by	ADP
aji-171	337	25	multiple	multiple	ADJ
aji-171	337	26	research	research	NOUN
aji-171	337	27	institutions	institution	NOUN
aji-171	337	28	,	,	PUNCT
aji-171	337	29	is	be	AUX
aji-171	337	30	a	a	DET
aji-171	337	31	major	major	ADJ
aji-171	337	32	barrier	barrier	NOUN
aji-171	337	33	.	.	PUNCT
aji-171	338	1	this	this	PRON
aji-171	338	2	is	be	AUX
aji-171	338	3	the	the	DET
aji-171	338	4	biggest	big	ADJ
aji-171	338	5	obstacle	obstacle	NOUN
aji-171	338	6	to	to	PART
aji-171	338	7	progress	progress	VERB
aji-171	338	8	in	in	ADP
aji-171	338	9	this	this	DET
aji-171	338	10	field	field	NOUN
aji-171	338	11	.	.	PUNCT
aji-171	339	1	other	other	ADJ
aji-171	339	2	factors	factor	NOUN
aji-171	339	3	,	,	PUNCT
aji-171	339	4	such	such	ADJ
aji-171	339	5	as	as	ADP
aji-171	339	6	sample	sample	NOUN
aji-171	339	7	preparation	preparation	NOUN
aji-171	339	8	,	,	PUNCT
aji-171	339	9	sample	sample	NOUN
aji-171	339	10	matrix	matrix	NOUN
aji-171	339	11	,	,	PUNCT
aji-171	339	12	and	and	CCONJ
aji-171	339	13	residual	residual	ADJ
aji-171	339	14	effects	effect	NOUN
aji-171	339	15	,	,	PUNCT
aji-171	339	16	can	can	AUX
aji-171	339	17	also	also	ADV
aji-171	339	18	contribute	contribute	VERB
aji-171	339	19	to	to	ADP
aji-171	339	20	data	datum	NOUN
aji-171	339	21	variability	variability	NOUN
aji-171	339	22	.	.	PUNCT
aji-171	340	1	to	to	PART
aji-171	340	2	overcome	overcome	VERB
aji-171	340	3	these	these	DET
aji-171	340	4	challenges	challenge	NOUN
aji-171	340	5	,	,	PUNCT
aji-171	340	6	it	it	PRON
aji-171	340	7	is	be	AUX
aji-171	340	8	essential	essential	ADJ
aji-171	340	9	to	to	PART
aji-171	340	10	switch	switch	VERB
aji-171	340	11	from	from	ADP
aji-171	340	12	calculating	calculate	VERB
aji-171	340	13	relative	relative	ADJ
aji-171	340	14	metabolite	metabolite	NOUN
aji-171	340	15	concentrations	concentration	NOUN
aji-171	340	16	to	to	ADP
aji-171	340	17	more	more	ADV
aji-171	340	18	accurate	accurate	ADJ
aji-171	340	19	absolute	absolute	ADJ
aji-171	340	20	concentration	concentration	NOUN
aji-171	340	21	measurements	measurement	NOUN
aji-171	340	22	,	,	PUNCT
aji-171	340	23	regardless	regardless	ADV
aji-171	340	24	of	of	ADP
aji-171	340	25	the	the	DET
aji-171	340	26	analytical	analytical	ADJ
aji-171	340	27	platform	platform	NOUN
aji-171	340	28	,	,	PUNCT
aji-171	340	29	approach	approach	NOUN
aji-171	340	30	,	,	PUNCT
aji-171	340	31	and	and	CCONJ
aji-171	340	32	procedure	procedure	NOUN
aji-171	340	33	.	.	PUNCT
aji-171	341	1	this	this	DET
aji-171	341	2	approach	approach	NOUN
aji-171	341	3	is	be	AUX
aji-171	341	4	important	important	ADJ
aji-171	341	5	even	even	ADV
aji-171	341	6	though	though	SCONJ
aji-171	341	7	ms	ms	PROPN
aji-171	341	8	finds	find	VERB
aji-171	341	9	it	it	PRON
aji-171	341	10	difficult	difficult	ADJ
aji-171	341	11	.	.	PUNCT
aji-171	342	1	8	8	X
aji-171	342	2	.	.	X
aji-171	342	3	conclusion	conclusion	NOUN
aji-171	342	4	a	a	DET
aji-171	342	5	helpful	helpful	ADJ
aji-171	342	6	method	method	NOUN
aji-171	342	7	for	for	ADP
aji-171	342	8	identifying	identify	VERB
aji-171	342	9	disease	disease	NOUN
aji-171	342	10	-	-	PUNCT
aji-171	342	11	related	relate	VERB
aji-171	342	12	metabolites	metabolite	NOUN
aji-171	342	13	in	in	ADP
aji-171	342	14	biofluids	biofluid	NOUN
aji-171	342	15	or	or	CCONJ
aji-171	342	16	tissue	tissue	NOUN
aji-171	342	17	as	as	ADV
aji-171	342	18	well	well	ADV
aji-171	342	19	as	as	ADP
aji-171	342	20	for	for	ADP
aji-171	342	21	classifying	classify	VERB
aji-171	342	22	and/or	and/or	CCONJ
aji-171	342	23	characterizing	characterize	VERB
aji-171	342	24	molecular	molecular	ADJ
aji-171	342	25	patterns	pattern	NOUN
aji-171	342	26	linked	link	VERB
aji-171	342	27	to	to	ADP
aji-171	342	28	disease	disease	NOUN
aji-171	342	29	or	or	CCONJ
aji-171	342	30	treatment	treatment	NOUN
aji-171	342	31	that	that	PRON
aji-171	342	32	are	be	AUX
aji-171	342	33	produced	produce	VERB
aji-171	342	34	from	from	ADP
aji-171	342	35	metabolites	metabolite	NOUN
aji-171	342	36	is	be	AUX
aji-171	342	37	mass	mass	ADJ
aji-171	342	38	spectrometry	spectrometry	NOUN
aji-171	342	39	(	(	PUNCT
aji-171	342	40	ms	ms	NOUN
aji-171	342	41	)	)	PUNCT
aji-171	342	42	based	base	VERB
aji-171	342	43	metabolomics	metabolomic	NOUN
aji-171	342	44	/	/	SYM
aji-171	342	45	lipid	lipid	NOUN
aji-171	342	46	omics	omic	NOUN
aji-171	342	47	.	.	PUNCT
aji-171	343	1	we	we	PRON
aji-171	343	2	continue	continue	VERB
aji-171	343	3	to	to	PART
aji-171	343	4	discover	discover	VERB
aji-171	343	5	new	new	ADJ
aji-171	343	6	biomarkers	biomarker	NOUN
aji-171	343	7	in	in	ADP
aji-171	343	8	metabolomics	metabolomic	NOUN
aji-171	343	9	that	that	PRON
aji-171	343	10	redefine	redefine	VERB
aji-171	343	11	health	health	NOUN
aji-171	343	12	and	and	CCONJ
aji-171	343	13	disease	disease	NOUN
aji-171	343	14	diagnostic	diagnostic	ADJ
aji-171	343	15	precision	precision	NOUN
aji-171	343	16	and	and	CCONJ
aji-171	343	17	provide	provide	VERB
aji-171	343	18	insight	insight	NOUN
aji-171	343	19	into	into	ADP
aji-171	343	20	the	the	DET
aji-171	343	21	biochemical	biochemical	ADJ
aji-171	343	22	etiology	etiology	NOUN
aji-171	343	23	of	of	ADP
aji-171	343	24	a	a	DET
aji-171	343	25	wide	wide	ADJ
aji-171	343	26	range	range	NOUN
aji-171	343	27	of	of	ADP
aji-171	343	28	diseases	disease	NOUN
aji-171	343	29	.	.	PUNCT
aji-171	344	1	this	this	PRON
aji-171	344	2	makes	make	VERB
aji-171	344	3	metabolomics	metabolomic	NOUN
aji-171	344	4	a	a	DET
aji-171	344	5	potentially	potentially	ADV
aji-171	344	6	useful	useful	ADJ
aji-171	344	7	platform	platform	NOUN
aji-171	344	8	for	for	ADP
aji-171	344	9	prognosis	prognosis	NOUN
aji-171	344	10	,	,	PUNCT
aji-171	344	11	early	early	ADJ
aji-171	344	12	detection	detection	NOUN
aji-171	344	13	,	,	PUNCT
aji-171	344	14	and	and	CCONJ
aji-171	344	15	the	the	DET
aji-171	344	16	application	application	NOUN
aji-171	344	17	of	of	ADP
aji-171	344	18	tailored	tailor	VERB
aji-171	344	19	treatment	treatment	NOUN
aji-171	344	20	plans	plan	NOUN
aji-171	344	21	founded	found	VERB
aji-171	344	22	on	on	ADP
aji-171	344	23	a	a	DET
aji-171	344	24	thorough	thorough	ADJ
aji-171	344	25	comprehension	comprehension	NOUN
aji-171	344	26	of	of	ADP
aji-171	344	27	metabolic	metabolic	NOUN
aji-171	344	28	changes	change	NOUN
aji-171	344	29	brought	bring	VERB
aji-171	344	30	on	on	ADP
aji-171	344	31	by	by	ADP
aji-171	344	32	illness	illness	NOUN
aji-171	344	33	and	and	CCONJ
aji-171	344	34	environmental	environmental	ADJ
aji-171	344	35	influences	influence	NOUN
aji-171	344	36	.	.	PUNCT
aji-171	345	1	the	the	DET
aji-171	345	2	metabolic	metabolic	NOUN
aji-171	345	3	profiling	profile	VERB
aji-171	345	4	biomarkers	biomarker	NOUN
aji-171	345	5	have	have	VERB
aji-171	345	6	the	the	DET
aji-171	345	7	potential	potential	NOUN
aji-171	345	8	to	to	PART
aji-171	345	9	improve	improve	VERB
aji-171	345	10	diagnosis	diagnosis	NOUN
aji-171	345	11	and	and	CCONJ
aji-171	345	12	enable	enable	VERB
aji-171	345	13	targeted	targeted	ADJ
aji-171	345	14	interventions	intervention	NOUN
aji-171	345	15	in	in	ADP
aji-171	345	16	metabolic	metabolic	NOUN
aji-171	345	17	syndromes	syndrome	NOUN
aji-171	345	18	,	,	PUNCT
aji-171	345	19	cancers	cancer	NOUN
aji-171	345	20	,	,	PUNCT
aji-171	345	21	cardiovascular	cardiovascular	ADJ
aji-171	345	22	diseases	disease	NOUN
aji-171	345	23	,	,	PUNCT
aji-171	345	24	and	and	CCONJ
aji-171	345	25	neurodegenerative	neurodegenerative	ADJ
aji-171	345	26	disorders	disorder	NOUN
aji-171	345	27	.	.	PUNCT
aji-171	346	1	but	but	CCONJ
aji-171	346	2	before	before	SCONJ
aji-171	346	3	the	the	DET
aji-171	346	4	biomarkers	biomarker	NOUN
aji-171	346	5	can	can	AUX
aji-171	346	6	truly	truly	ADV
aji-171	346	7	reach	reach	VERB
aji-171	346	8	the	the	DET
aji-171	346	9	clinic	clinic	NOUN
aji-171	346	10	,	,	PUNCT
aji-171	346	11	a	a	DET
aji-171	346	12	lot	lot	NOUN
aji-171	346	13	more	more	ADJ
aji-171	346	14	work	work	NOUN
aji-171	346	15	needs	need	VERB
aji-171	346	16	to	to	PART
aji-171	346	17	be	be	AUX
aji-171	346	18	done	do	VERB
aji-171	346	19	.	.	PUNCT
aji-171	347	1	to	to	PART
aji-171	347	2	ensure	ensure	VERB
aji-171	347	3	that	that	SCONJ
aji-171	347	4	the	the	DET
aji-171	347	5	biomarkers	biomarker	NOUN
aji-171	347	6	are	be	AUX
aji-171	347	7	accurate	accurate	ADJ
aji-171	347	8	and	and	CCONJ
aji-171	347	9	repeatable	repeatable	ADJ
aji-171	347	10	across	across	ADP
aji-171	347	11	a	a	DET
aji-171	347	12	range	range	NOUN
aji-171	347	13	of	of	ADP
aji-171	347	14	populations	population	NOUN
aji-171	347	15	,	,	PUNCT
aji-171	347	16	considerable	considerable	ADJ
aji-171	347	17	attention	attention	NOUN
aji-171	347	18	must	must	AUX
aji-171	347	19	be	be	AUX
aji-171	347	20	paid	pay	VERB
aji-171	347	21	to	to	ADP
aji-171	347	22	inter	inter	ADJ
aji-171	347	23	-	-	ADJ
aji-171	347	24	individual	individual	ADJ
aji-171	347	25	variability	variability	NOUN
aji-171	347	26	,	,	PUNCT
aji-171	347	27	environmental	environmental	ADJ
aji-171	347	28	factors	factor	NOUN
aji-171	347	29	,	,	PUNCT
aji-171	347	30	and	and	CCONJ
aji-171	347	31	data	datum	NOUN
aji-171	347	32	complexity	complexity	NOUN
aji-171	347	33	in	in	ADP
aji-171	347	34	metabolomics	metabolomic	NOUN
aji-171	347	35	.	.	PUNCT
aji-171	348	1	confounding	confound	VERB
aji-171	348	2	factor	factor	NOUN
aji-171	348	3	considerations	consideration	NOUN
aji-171	348	4	and	and	CCONJ
aji-171	348	5	a	a	DET
aji-171	348	6	strict	strict	ADJ
aji-171	348	7	methodology	methodology	NOUN
aji-171	348	8	in	in	ADP
aji-171	348	9	biomarker	biomarker	NOUN
aji-171	348	10	validation	validation	NOUN
aji-171	348	11	with	with	ADP
aji-171	348	12	large	large	ADJ
aji-171	348	13	cohorts	cohort	NOUN
aji-171	348	14	are	be	AUX
aji-171	348	15	necessary	necessary	ADJ
aji-171	348	16	for	for	ADP
aji-171	348	17	that	that	PRON
aji-171	348	18	.	.	PUNCT
aji-171	349	1	depending	depend	VERB
aji-171	349	2	on	on	ADP
aji-171	349	3	the	the	DET
aji-171	349	4	features	feature	NOUN
aji-171	349	5	of	of	ADP
aji-171	349	6	metabolic	metabolic	NOUN
aji-171	349	7	profiles	profile	NOUN
aji-171	349	8	,	,	PUNCT
aji-171	349	9	biomarker	biomarker	NOUN
aji-171	349	10	-	-	PUNCT
aji-171	349	11	focused	focus	VERB
aji-171	349	12	research	research	NOUN
aji-171	349	13	and	and	CCONJ
aji-171	349	14	translation	translation	NOUN
aji-171	349	15	to	to	ADP
aji-171	349	16	clinical	clinical	ADJ
aji-171	349	17	practice	practice	NOUN
aji-171	349	18	are	be	AUX
aji-171	349	19	constantly	constantly	ADV
aji-171	349	20	pushing	push	VERB
aji-171	349	21	this	this	DET
aji-171	349	22	field	field	NOUN
aji-171	349	23	away	away	ADV
aji-171	349	24	from	from	ADP
aji-171	349	25	standard	standard	ADJ
aji-171	349	26	treatment	treatment	NOUN
aji-171	349	27	and	and	CCONJ
aji-171	349	28	toward	toward	ADP
aji-171	349	29	personalized	personalized	ADJ
aji-171	349	30	therapies	therapy	NOUN
aji-171	349	31	.	.	PUNCT
aji-171	350	1	in	in	ADP
aji-171	350	2	order	order	NOUN
aji-171	350	3	to	to	PART
aji-171	350	4	translate	translate	VERB
aji-171	350	5	biomarkers	biomarker	NOUN
aji-171	350	6	from	from	ADP
aji-171	350	7	metabolomics	metabolomic	NOUN
aji-171	350	8	into	into	ADP
aji-171	350	9	clinical	clinical	ADJ
aji-171	350	10	practices	practice	NOUN
aji-171	350	11	for	for	ADP
aji-171	350	12	improved	improved	ADJ
aji-171	350	13	patient	patient	ADJ
aji-171	350	14	outcomes	outcome	NOUN
aji-171	350	15	and	and	CCONJ
aji-171	350	16	to	to	PART
aji-171	350	17	steer	steer	VERB
aji-171	350	18	the	the	DET
aji-171	350	19	trajectory	trajectory	NOUN
aji-171	350	20	of	of	ADP
aji-171	350	21	precision	precision	NOUN
aji-171	350	22	medicine	medicine	NOUN
aji-171	350	23	,	,	PUNCT
aji-171	350	24	it	it	PRON
aji-171	350	25	will	will	AUX
aji-171	350	26	be	be	AUX
aji-171	350	27	necessary	necessary	ADJ
aji-171	350	28	to	to	PART
aji-171	350	29	overcome	overcome	VERB
aji-171	350	30	many	many	ADJ
aji-171	350	31	of	of	ADP
aji-171	350	32	the	the	DET
aji-171	350	33	current	current	ADJ
aji-171	350	34	obstacles	obstacle	NOUN
aji-171	350	35	through	through	ADP
aji-171	350	36	ongoing	ongoing	ADJ
aji-171	350	37	research	research	NOUN
aji-171	350	38	and	and	CCONJ
aji-171	350	39	collaboration	collaboration	NOUN
aji-171	350	40	among	among	ADP
aji-171	350	41	clinicians	clinician	NOUN
aji-171	350	42	,	,	PUNCT
aji-171	350	43	researchers	researcher	NOUN
aji-171	350	44	,	,	PUNCT
aji-171	350	45	and	and	CCONJ
aji-171	350	46	technologists	technologist	NOUN
aji-171	350	47	.	.	PUNCT
aji-171	351	1	disclaimer	disclaimer	NOUN
aji-171	351	2	(	(	PUNCT
aji-171	351	3	artificial	artificial	ADJ
aji-171	351	4	intelligence	intelligence	NOUN
aji-171	351	5	)	)	PUNCT
aji-171	351	6	author(s	author(s	NOUN
aji-171	351	7	)	)	PUNCT
aji-171	351	8	hereby	hereby	ADV
aji-171	351	9	declare	declare	VERB
aji-171	351	10	that	that	SCONJ
aji-171	351	11	no	no	DET
aji-171	351	12	generative	generative	NOUN
aji-171	351	13	ai	ai	VERB
aji-171	351	14	technologies	technology	NOUN
aji-171	351	15	such	such	ADJ
aji-171	351	16	as	as	ADP
aji-171	351	17	large	large	ADJ
aji-171	351	18	language	language	NOUN
aji-171	351	19	models	model	NOUN
aji-171	351	20	(	(	PUNCT
aji-171	351	21	chatgpt	chatgpt	NOUN
aji-171	351	22	,	,	PUNCT
aji-171	351	23	copilot	copilot	NOUN
aji-171	351	24	,	,	PUNCT
aji-171	351	25	etc	etc	X
aji-171	351	26	.	.	X
aji-171	351	27	)	)	PUNCT
aji-171	351	28	and	and	CCONJ
aji-171	351	29	text	text	NOUN
aji-171	351	30	-	-	PUNCT
aji-171	351	31	to	to	ADP
aji-171	351	32	-	-	PUNCT
aji-171	351	33	image	image	NOUN
aji-171	351	34	generators	generator	NOUN
aji-171	351	35	have	have	AUX
aji-171	351	36	been	be	AUX
aji-171	351	37	used	use	VERB
aji-171	351	38	during	during	ADP
aji-171	351	39	the	the	DET
aji-171	351	40	writing	writing	NOUN
aji-171	351	41	or	or	CCONJ
aji-171	351	42	editing	editing	NOUN
aji-171	351	43	of	of	ADP
aji-171	351	44	this	this	DET
aji-171	351	45	manuscript	manuscript	NOUN
aji-171	351	46	.	.	PUNCT
aji-171	352	1	consent	consent	NOUN
aji-171	352	2	it	it	PRON
aji-171	352	3	is	be	AUX
aji-171	352	4	not	not	PART
aji-171	352	5	applicable	applicable	ADJ
aji-171	352	6	.	.	PUNCT
aji-171	353	1	ethical	ethical	ADJ
aji-171	353	2	approval	approval	NOUN
aji-171	353	3	it	it	PRON
aji-171	353	4	is	be	AUX
aji-171	353	5	not	not	PART
aji-171	353	6	applicable	applicable	ADJ
aji-171	353	7	.	.	PUNCT
aji-171	354	1	competing	compete	VERB
aji-171	354	2	interests	interest	NOUN
aji-171	354	3	authors	author	NOUN
aji-171	354	4	have	have	AUX
aji-171	354	5	declared	declare	VERB
aji-171	354	6	that	that	SCONJ
aji-171	354	7	no	no	DET
aji-171	354	8	competing	compete	VERB
aji-171	354	9	interests	interest	NOUN
aji-171	354	10	exist	exist	VERB
aji-171	354	11	.	.	PUNCT
aji-171	355	1	references	reference	NOUN
aji-171	355	2	abi	abi	PROPN
aji-171	355	3	-	-	PUNCT
aji-171	355	4	dargham	dargham	PROPN
aji-171	355	5	,	,	PUNCT
aji-171	355	6	a.	a.	NOUN
aji-171	355	7	,	,	PUNCT
aji-171	355	8	moeller	moeller	PROPN
aji-171	355	9	,	,	PUNCT
aji-171	355	10	s.	s.	PROPN
aji-171	355	11	j.	j.	PROPN
aji-171	355	12	,	,	PUNCT
aji-171	355	13	ali	ali	PROPN
aji-171	355	14	,	,	PUNCT
aji-171	355	15	f.	f.	PROPN
aji-171	355	16	,	,	PUNCT
aji-171	355	17	delorenzo	delorenzo	NOUN
aji-171	355	18	,	,	PUNCT
aji-171	355	19	c.	c.	NOUN
aji-171	355	20	,	,	PUNCT
aji-171	355	21	domschke	domschke	NOUN
aji-171	355	22	,	,	PUNCT
aji-171	355	23	k.	k.	PROPN
aji-171	355	24	,	,	PUNCT
aji-171	355	25	horga	horga	PROPN
aji-171	355	26	,	,	PUNCT
aji-171	355	27	g.	g.	PROPN
aji-171	355	28	,	,	PUNCT
aji-171	355	29	jutla	jutla	PROPN
aji-171	355	30	,	,	PUNCT
aji-171	355	31	a.	a.	NOUN
aji-171	355	32	,	,	PUNCT
aji-171	355	33	kotov	kotov	PROPN
aji-171	355	34	,	,	PUNCT
aji-171	355	35	r.	r.	PROPN
aji-171	355	36	,	,	PUNCT
aji-171	355	37	paulus	paulus	PROPN
aji-171	355	38	,	,	PUNCT
aji-171	355	39	m.	m.	NOUN
aji-171	355	40	p.	p.	PROPN
aji-171	355	41	,	,	PUNCT
aji-171	355	42	&	&	CCONJ
aji-171	355	43	rubio	rubio	PROPN
aji-171	355	44	,	,	PUNCT
aji-171	355	45	j.	j.	PROPN
aji-171	355	46	m.	m.	PROPN
aji-171	355	47	(	(	PUNCT
aji-171	355	48	2023	2023	NUM
aji-171	355	49	)	)	PUNCT
aji-171	355	50	.	.	PUNCT
aji-171	356	1	candidate	candidate	NOUN
aji-171	356	2	biomarkers	biomarker	NOUN
aji-171	356	3	in	in	ADP
aji-171	356	4	psychiatric	psychiatric	ADJ
aji-171	356	5	disorders	disorder	NOUN
aji-171	356	6	:	:	PUNCT
aji-171	356	7	state	state	NOUN
aji-171	356	8	of	of	ADP
aji-171	356	9	the	the	DET
aji-171	356	10	field	field	NOUN
aji-171	356	11	.	.	PUNCT
aji-171	357	1	world	world	NOUN
aji-171	357	2	psychiatry	psychiatry	PROPN
aji-171	357	3	,	,	PUNCT
aji-171	357	4	22	22	NUM
aji-171	357	5	,	,	PUNCT
aji-171	357	6	236–262	236–262	NUM
aji-171	357	7	.	.	PUNCT
aji-171	357	8	ahanger	ahanger	PROPN
aji-171	357	9	,	,	PUNCT
aji-171	357	10	i.	i.	PROPN
aji-171	357	11	a.	a.	PROPN
aji-171	357	12	,	,	PUNCT
aji-171	357	13	bashir	bashir	PROPN
aji-171	357	14	,	,	PUNCT
aji-171	357	15	b.	b.	PROPN
aji-171	357	16	,	,	PUNCT
aji-171	357	17	wani	wani	PROPN
aji-171	357	18	,	,	PUNCT
aji-171	357	19	o.	o.	PROPN
aji-171	357	20	h.	h.	PROPN
aji-171	357	21	,	,	PUNCT
aji-171	357	22	hajam	hajam	PROPN
aji-171	357	23	,	,	PUNCT
aji-171	357	24	i.	i.	PROPN
aji-171	357	25	b.	b.	PROPN
aji-171	357	26	,	,	PUNCT
aji-171	357	27	&	&	CCONJ
aji-171	357	28	dar	dar	PROPN
aji-171	357	29	,	,	PUNCT
aji-171	357	30	t.	t.	NOUN
aji-171	357	31	a.	a.	NOUN
aji-171	357	32	(	(	PUNCT
aji-171	357	33	2024	2024	NUM
aji-171	357	34	)	)	PUNCT
aji-171	357	35	.	.	PUNCT
aji-171	358	1	diverse	diverse	ADJ
aji-171	358	2	biological	biological	ADJ
aji-171	358	3	functions	function	NOUN
aji-171	358	4	of	of	ADP
aji-171	358	5	myo	myo	NOUN
aji-171	358	6	-	-	PUNCT
aji-171	358	7	inositol	inositol	NOUN
aji-171	358	8	:	:	PUNCT
aji-171	358	9	a	a	DET
aji-171	358	10	neurometabolite	neurometabolite	ADJ
aji-171	358	11	,	,	PUNCT
aji-171	358	12	osmoprotectant	osmoprotectant	ADJ
aji-171	358	13	,	,	PUNCT
aji-171	358	14	and	and	CCONJ
aji-171	358	15	diagnostic	diagnostic	ADJ
aji-171	358	16	marker	marker	NOUN
aji-171	358	17	.	.	PUNCT
aji-171	359	1	in	in	ADP
aji-171	359	2	cellular	cellular	ADJ
aji-171	359	3	osmolytes	osmolyte	NOUN
aji-171	359	4	:	:	PUNCT
aji-171	359	5	from	from	ADP
aji-171	359	6	chaperoning	chaperone	VERB
aji-171	359	7	protein	protein	NOUN
aji-171	359	8	folding	fold	VERB
aji-171	359	9	to	to	ADP
aji-171	359	10	clinical	clinical	ADJ
aji-171	359	11	perspectives	perspective	NOUN
aji-171	359	12	(	(	PUNCT
aji-171	359	13	pp	pp	ADJ
aji-171	359	14	.	.	PUNCT
aji-171	360	1	161–183	161–183	NUM
aji-171	360	2	)	)	PUNCT
aji-171	360	3	.	.	PUNCT
aji-171	361	1	springer	springer	NOUN
aji-171	361	2	:	:	PUNCT
aji-171	361	3	berlin	berlin	PROPN
aji-171	361	4	/	/	SYM
aji-171	361	5	heidelberg	heidelberg	PROPN
aji-171	361	6	,	,	PUNCT
aji-171	361	7	germany	germany	PROPN
aji-171	361	8	.	.	PUNCT
aji-171	362	1	mamman	mamman	PROPN
aji-171	362	2	et	et	PROPN
aji-171	362	3	al	al	PROPN
aji-171	362	4	.	.	PROPN
aji-171	362	5	;	;	PUNCT
aji-171	362	6	asian	asian	PROPN
aji-171	362	7	j.	j.	PROPN
aji-171	362	8	immunol	immunol	PROPN
aji-171	362	9	.	.	PROPN
aji-171	362	10	,	,	PUNCT
aji-171	362	11	vol	vol	NOUN
aji-171	362	12	.	.	PROPN
aji-171	362	13	8	8	NUM
aji-171	362	14	,	,	PUNCT
aji-171	362	15	no	no	INTJ
aji-171	362	16	.	.	NOUN
aji-171	362	17	1	1	NUM
aji-171	362	18	,	,	PUNCT
aji-171	362	19	pp	pp	ADJ
aji-171	362	20	.	.	PUNCT
aji-171	363	1	190	190	NUM
aji-171	363	2	-	-	SYM
aji-171	363	3	206	206	NUM
aji-171	363	4	,	,	PUNCT
aji-171	363	5	2025	2025	NUM
aji-171	363	6	;	;	PUNCT
aji-171	363	7	article	article	NOUN
aji-171	363	8	no.aji.140476	no.aji.140476	NOUN
aji-171	363	9	201	201	NUM
aji-171	363	10	andersson	andersson	PROPN
aji-171	363	11	-	-	PUNCT
aji-171	363	12	hall	hall	PROPN
aji-171	363	13	,	,	PUNCT
aji-171	363	14	u.	u.	PROPN
aji-171	363	15	,	,	PUNCT
aji-171	363	16	gustavsson	gustavsson	PROPN
aji-171	363	17	,	,	PUNCT
aji-171	363	18	c.	c.	PROPN
aji-171	363	19	,	,	PUNCT
aji-171	363	20	pedersen	pedersen	PROPN
aji-171	363	21	,	,	PUNCT
aji-171	363	22	a.	a.	NOUN
aji-171	363	23	,	,	PUNCT
aji-171	363	24	malmodin	malmodin	PROPN
aji-171	363	25	,	,	PUNCT
aji-171	363	26	d.	d.	PROPN
aji-171	363	27	,	,	PUNCT
aji-171	363	28	joelsson	joelsson	PROPN
aji-171	363	29	,	,	PUNCT
aji-171	363	30	l.	l.	PROPN
aji-171	363	31	,	,	PUNCT
aji-171	363	32	&	&	CCONJ
aji-171	363	33	holmäng	holmäng	PROPN
aji-171	363	34	,	,	PUNCT
aji-171	363	35	a.	a.	NOUN
aji-171	363	36	(	(	PUNCT
aji-171	363	37	2018	2018	NUM
aji-171	363	38	)	)	PUNCT
aji-171	363	39	.	.	PUNCT
aji-171	364	1	higher	high	ADJ
aji-171	364	2	concentrations	concentration	NOUN
aji-171	364	3	of	of	ADP
aji-171	364	4	bcaas	bcaas	NOUN
aji-171	364	5	and	and	CCONJ
aji-171	364	6	3	3	NUM
aji-171	364	7	-	-	NOUN
aji-171	364	8	hib	hib	NOUN
aji-171	364	9	are	be	AUX
aji-171	364	10	associated	associate	VERB
aji-171	364	11	with	with	ADP
aji-171	364	12	insulin	insulin	NOUN
aji-171	364	13	resistance	resistance	NOUN
aji-171	364	14	in	in	ADP
aji-171	364	15	the	the	DET
aji-171	364	16	transition	transition	NOUN
aji-171	364	17	from	from	ADP
aji-171	364	18	gestational	gestational	ADJ
aji-171	364	19	diabetes	diabete	NOUN
aji-171	364	20	to	to	PART
aji-171	364	21	type	type	VERB
aji-171	364	22	2	2	NUM
aji-171	364	23	diabetes	diabetes	NOUN
aji-171	364	24	.	.	PUNCT
aji-171	365	1	journal	journal	NOUN
aji-171	365	2	of	of	ADP
aji-171	365	3	diabetes	diabetes	NOUN
aji-171	365	4	research	research	NOUN
aji-171	365	5	,	,	PUNCT
aji-171	365	6	4207067	4207067	NUM
aji-171	365	7	.	.	PUNCT
aji-171	366	1	averina	averina	PROPN
aji-171	366	2	,	,	PUNCT
aji-171	366	3	o.	o.	PROPN
aji-171	366	4	v.	v.	PROPN
aji-171	366	5	,	,	PUNCT
aji-171	366	6	poluektova	poluektova	PROPN
aji-171	366	7	,	,	PUNCT
aji-171	366	8	e.	e.	PROPN
aji-171	366	9	u.	u.	PROPN
aji-171	366	10	,	,	PUNCT
aji-171	366	11	zorkina	zorkina	PROPN
aji-171	366	12	,	,	PUNCT
aji-171	366	13	y.	y.	PROPN
aji-171	366	14	a.	a.	PROPN
aji-171	366	15	,	,	PUNCT
aji-171	366	16	kovtun	kovtun	PROPN
aji-171	366	17	,	,	PUNCT
aji-171	366	18	a.	a.	PROPN
aji-171	366	19	s.	s.	PROPN
aji-171	366	20	,	,	PUNCT
aji-171	366	21	&	&	CCONJ
aji-171	366	22	danilenko	danilenko	PROPN
aji-171	366	23	,	,	PUNCT
aji-171	366	24	v.	v.	ADP
aji-171	366	25	n.	n.	PROPN
aji-171	366	26	(	(	PUNCT
aji-171	366	27	2024	2024	NUM
aji-171	366	28	)	)	PUNCT
aji-171	366	29	.	.	PUNCT
aji-171	367	1	human	human	ADJ
aji-171	367	2	gut	gut	NOUN
aji-171	367	3	microbiota	microbiota	NOUN
aji-171	367	4	for	for	ADP
aji-171	367	5	diagnosis	diagnosis	NOUN
aji-171	367	6	and	and	CCONJ
aji-171	367	7	treatment	treatment	NOUN
aji-171	367	8	of	of	ADP
aji-171	367	9	depression	depression	NOUN
aji-171	367	10	.	.	PUNCT
aji-171	368	1	international	international	ADJ
aji-171	368	2	journal	journal	NOUN
aji-171	368	3	of	of	ADP
aji-171	368	4	molecular	molecular	ADJ
aji-171	368	5	science	science	NOUN
aji-171	368	6	,	,	PUNCT
aji-171	368	7	25	25	NUM
aji-171	368	8	,	,	PUNCT
aji-171	368	9	5782	5782	NUM
aji-171	368	10	.	.	PUNCT
aji-171	369	1	barupal	barupal	NOUN
aji-171	369	2	,	,	PUNCT
aji-171	369	3	d.	d.	PROPN
aji-171	369	4	k.	k.	PROPN
aji-171	369	5	(	(	PUNCT
aji-171	369	6	2022	2022	NUM
aji-171	369	7	)	)	PUNCT
aji-171	369	8	.	.	PUNCT
aji-171	370	1	response	response	NOUN
aji-171	370	2	:	:	PUNCT
aji-171	370	3	commentary	commentary	NOUN
aji-171	370	4	:	:	PUNCT
aji-171	370	5	data	datum	NOUN
aji-171	370	6	processing	processing	NOUN
aji-171	370	7	thresholds	threshold	NOUN
aji-171	370	8	for	for	ADP
aji-171	370	9	abundance	abundance	NOUN
aji-171	370	10	and	and	CCONJ
aji-171	370	11	sparsity	sparsity	NOUN
aji-171	370	12	and	and	CCONJ
aji-171	370	13	missed	miss	VERB
aji-171	370	14	biological	biological	ADJ
aji-171	370	15	insights	insight	NOUN
aji-171	370	16	in	in	ADP
aji-171	370	17	an	an	DET
aji-171	370	18	untargeted	untargeted	ADJ
aji-171	370	19	chemical	chemical	NOUN
aji-171	370	20	analysis	analysis	NOUN
aji-171	370	21	of	of	ADP
aji-171	370	22	blood	blood	NOUN
aji-171	370	23	specimens	specimen	NOUN
aji-171	370	24	for	for	ADP
aji-171	370	25	exposomics	exposomic	NOUN
aji-171	370	26	.	.	PUNCT
aji-171	371	1	frontiers	frontier	NOUN
aji-171	371	2	in	in	ADP
aji-171	371	3	public	public	ADJ
aji-171	371	4	health	health	NOUN
aji-171	371	5	,	,	PUNCT
aji-171	371	6	10	10	NUM
aji-171	371	7	,	,	PUNCT
aji-171	371	8	1003148	1003148	NUM
aji-171	371	9	.	.	PUNCT
aji-171	372	1	https://doi.org/10.3389/fpubh.2022.100314	https://doi.org/10.3389/fpubh.2022.100314	PROPN
aji-171	372	2	8	8	NUM
aji-171	372	3	beger	beger	NOUN
aji-171	372	4	,	,	PUNCT
aji-171	372	5	r.	r.	PROPN
aji-171	372	6	d.	d.	PROPN
aji-171	372	7	,	,	PUNCT
aji-171	372	8	dunn	dunn	PROPN
aji-171	372	9	,	,	PUNCT
aji-171	372	10	w.	w.	PROPN
aji-171	372	11	,	,	PUNCT
aji-171	372	12	schmidt	schmidt	PROPN
aji-171	372	13	,	,	PUNCT
aji-171	372	14	m.	m.	NOUN
aji-171	372	15	a.	a.	PROPN
aji-171	372	16	,	,	PUNCT
aji-171	372	17	gross	gross	PROPN
aji-171	372	18	,	,	PUNCT
aji-171	372	19	s.	s.	PROPN
aji-171	372	20	s.	s.	PROPN
aji-171	372	21	,	,	PUNCT
aji-171	372	22	kirwan	kirwan	PROPN
aji-171	372	23	,	,	PUNCT
aji-171	372	24	j.	j.	PROPN
aji-171	372	25	a.	a.	PROPN
aji-171	372	26	,	,	PUNCT
aji-171	372	27	cascante	cascante	NOUN
aji-171	372	28	,	,	PUNCT
aji-171	372	29	m.	m.	NOUN
aji-171	372	30	,	,	PUNCT
aji-171	372	31	brennan	brennan	PROPN
aji-171	372	32	,	,	PUNCT
aji-171	372	33	l.	l.	PROPN
aji-171	372	34	,	,	PUNCT
aji-171	372	35	wishart	wishart	PROPN
aji-171	372	36	,	,	PUNCT
aji-171	372	37	d.	d.	PROPN
aji-171	372	38	s.	s.	PROPN
aji-171	372	39	,	,	PUNCT
aji-171	372	40	oresic	oresic	ADJ
aji-171	372	41	,	,	PUNCT
aji-171	372	42	m.	m.	NOUN
aji-171	372	43	,	,	PUNCT
aji-171	372	44	&	&	CCONJ
aji-171	372	45	hankemeier	hankemeier	NOUN
aji-171	372	46	,	,	PUNCT
aji-171	372	47	t.	t.	PROPN
aji-171	372	48	(	(	PUNCT
aji-171	372	49	2016	2016	NUM
aji-171	372	50	)	)	PUNCT
aji-171	372	51	.	.	PUNCT
aji-171	373	1	metabolomics	metabolomic	NOUN
aji-171	373	2	enables	enable	VERB
aji-171	373	3	precision	precision	NOUN
aji-171	373	4	medicine	medicine	NOUN
aji-171	373	5	:	:	PUNCT
aji-171	373	6	“	"	PUNCT
aji-171	373	7	a	a	DET
aji-171	373	8	white	white	ADJ
aji-171	373	9	paper	paper	NOUN
aji-171	373	10	,	,	PUNCT
aji-171	373	11	community	community	NOUN
aji-171	373	12	perspective	perspective	NOUN
aji-171	373	13	”	"	PUNCT
aji-171	373	14	.	.	PUNCT
aji-171	374	1	metabolomics	metabolomic	NOUN
aji-171	374	2	,	,	PUNCT
aji-171	374	3	12	12	NUM
aji-171	374	4	,	,	PUNCT
aji-171	374	5	149	149	NUM
aji-171	374	6	.	.	PUNCT
aji-171	375	1	beloribi	beloribi	NOUN
aji-171	375	2	-	-	PUNCT
aji-171	375	3	djefaflia	djefaflia	PROPN
aji-171	375	4	,	,	PUNCT
aji-171	375	5	s.	s.	PROPN
aji-171	375	6	,	,	PUNCT
aji-171	375	7	vasseur	vasseur	PROPN
aji-171	375	8	,	,	PUNCT
aji-171	375	9	s.	s.	PROPN
aji-171	375	10	,	,	PUNCT
aji-171	375	11	&	&	CCONJ
aji-171	375	12	guillaumond	guillaumond	PROPN
aji-171	375	13	,	,	PUNCT
aji-171	375	14	f.	f.	PROPN
aji-171	375	15	(	(	PUNCT
aji-171	375	16	2016	2016	NUM
aji-171	375	17	)	)	PUNCT
aji-171	375	18	.	.	PUNCT
aji-171	376	1	lipid	lipid	PROPN
aji-171	376	2	metabolic	metabolic	NOUN
aji-171	376	3	reprogramming	reprogramme	VERB
aji-171	376	4	in	in	ADP
aji-171	376	5	cancer	cancer	NOUN
aji-171	376	6	cells	cell	NOUN
aji-171	376	7	.	.	PUNCT
aji-171	377	1	oncogenesis	oncogenesis	NOUN
aji-171	377	2	,	,	PUNCT
aji-171	377	3	5	5	NUM
aji-171	377	4	,	,	PUNCT
aji-171	377	5	189	189	NUM
aji-171	377	6	.	.	PUNCT
aji-171	377	7	borroni	borroni	PROPN
aji-171	377	8	,	,	PUNCT
aji-171	377	9	e.	e.	PROPN
aji-171	377	10	,	,	PUNCT
aji-171	377	11	frigerio	frigerio	PROPN
aji-171	377	12	,	,	PUNCT
aji-171	377	13	g.	g.	PROPN
aji-171	377	14	,	,	PUNCT
aji-171	377	15	polledri	polledri	PROPN
aji-171	377	16	,	,	PUNCT
aji-171	377	17	e.	e.	PROPN
aji-171	377	18	,	,	PUNCT
aji-171	377	19	mercadante	mercadante	PROPN
aji-171	377	20	,	,	PUNCT
aji-171	377	21	r.	r.	PROPN
aji-171	377	22	,	,	PUNCT
aji-171	377	23	maggioni	maggioni	NOUN
aji-171	377	24	,	,	PUNCT
aji-171	377	25	c.	c.	PROPN
aji-171	377	26	,	,	PUNCT
aji-171	377	27	fedrizzi	fedrizzi	NOUN
aji-171	377	28	,	,	PUNCT
aji-171	377	29	l.	l.	PROPN
aji-171	377	30	,	,	PUNCT
aji-171	377	31	pesatori	pesatori	PROPN
aji-171	377	32	,	,	PUNCT
aji-171	377	33	a.	a.	PROPN
aji-171	377	34	c.	c.	PROPN
aji-171	377	35	,	,	PUNCT
aji-171	377	36	fustinoni	fustinoni	NOUN
aji-171	377	37	,	,	PUNCT
aji-171	377	38	s.	s.	PROPN
aji-171	377	39	,	,	PUNCT
aji-171	377	40	&	&	CCONJ
aji-171	377	41	carugno	carugno	NOUN
aji-171	377	42	,	,	PUNCT
aji-171	377	43	m.	m.	NOUN
aji-171	377	44	(	(	PUNCT
aji-171	377	45	2023	2023	NUM
aji-171	377	46	)	)	PUNCT
aji-171	377	47	.	.	PUNCT
aji-171	378	1	metabolomic	metabolomic	ADJ
aji-171	378	2	profiles	profile	NOUN
aji-171	378	3	in	in	ADP
aji-171	378	4	night	night	NOUN
aji-171	378	5	shift	shift	NOUN
aji-171	378	6	workers	worker	NOUN
aji-171	378	7	:	:	PUNCT
aji-171	378	8	a	a	DET
aji-171	378	9	cross	cross	ADJ
aji-171	378	10	-	-	ADJ
aji-171	378	11	sectional	sectional	ADJ
aji-171	378	12	study	study	NOUN
aji-171	378	13	on	on	ADP
aji-171	378	14	hospital	hospital	NOUN
aji-171	378	15	female	female	ADJ
aji-171	378	16	nurses	nurse	NOUN
aji-171	378	17	.	.	PUNCT
aji-171	379	1	frontiers	frontier	NOUN
aji-171	379	2	in	in	ADP
aji-171	379	3	public	public	ADJ
aji-171	379	4	health	health	NOUN
aji-171	379	5	,	,	PUNCT
aji-171	379	6	11	11	NUM
aji-171	379	7	,	,	PUNCT
aji-171	379	8	1082074	1082074	NUM
aji-171	379	9	.	.	PUNCT
aji-171	380	1	https://doi.org/10.3389/fpubh.2023.108207	https://doi.org/10.3389/fpubh.2023.108207	PROPN
aji-171	380	2	4	4	NUM
aji-171	380	3	califf	califf	NOUN
aji-171	380	4	,	,	PUNCT
aji-171	380	5	r.	r.	PROPN
aji-171	380	6	m.	m.	PROPN
aji-171	380	7	(	(	PUNCT
aji-171	380	8	2018	2018	NUM
aji-171	380	9	)	)	PUNCT
aji-171	380	10	.	.	PUNCT
aji-171	381	1	biomarker	biomarker	NOUN
aji-171	381	2	definitions	definition	NOUN
aji-171	381	3	and	and	CCONJ
aji-171	381	4	their	their	PRON
aji-171	381	5	applications	application	NOUN
aji-171	381	6	.	.	PUNCT
aji-171	382	1	experimental	experimental	ADJ
aji-171	382	2	biology	biology	NOUN
aji-171	382	3	and	and	CCONJ
aji-171	382	4	medicine	medicine	NOUN
aji-171	382	5	(	(	PUNCT
aji-171	382	6	ebm	ebm	PROPN
aji-171	382	7	)	)	PUNCT
aji-171	382	8	,	,	PUNCT
aji-171	382	9	243	243	NUM
aji-171	382	10	,	,	PUNCT
aji-171	382	11	213–221	213–221	NUM
aji-171	382	12	.	.	PUNCT
aji-171	383	1	ceglarek	ceglarek	NOUN
aji-171	383	2	,	,	PUNCT
aji-171	383	3	u.	u.	PROPN
aji-171	383	4	,	,	PUNCT
aji-171	383	5	leichtle	leichtle	ADJ
aji-171	383	6	,	,	PUNCT
aji-171	383	7	a.	a.	NOUN
aji-171	383	8	,	,	PUNCT
aji-171	383	9	brügel	brügel	PROPN
aji-171	383	10	,	,	PUNCT
aji-171	383	11	m.	m.	NOUN
aji-171	383	12	,	,	PUNCT
aji-171	383	13	kortz	kortz	PROPN
aji-171	383	14	,	,	PUNCT
aji-171	383	15	l.	l.	PROPN
aji-171	383	16	,	,	PUNCT
aji-171	383	17	brauer	brauer	PROPN
aji-171	383	18	,	,	PUNCT
aji-171	383	19	r.	r.	PROPN
aji-171	383	20	,	,	PUNCT
aji-171	383	21	&	&	CCONJ
aji-171	383	22	bresler	bresler	PROPN
aji-171	383	23	,	,	PUNCT
aji-171	383	24	k.	k.	PROPN
aji-171	383	25	(	(	PUNCT
aji-171	383	26	2009	2009	NUM
aji-171	383	27	)	)	PUNCT
aji-171	383	28	.	.	PUNCT
aji-171	384	1	challenges	challenge	NOUN
aji-171	384	2	and	and	CCONJ
aji-171	384	3	developments	development	NOUN
aji-171	384	4	in	in	ADP
aji-171	384	5	tandem	tandem	PROPN
aji-171	384	6	mass	mass	PROPN
aji-171	384	7	spectrometry	spectrometry	NOUN
aji-171	384	8	based	base	VERB
aji-171	384	9	clinical	clinical	ADJ
aji-171	384	10	metabolomics	metabolomic	NOUN
aji-171	384	11	.	.	PUNCT
aji-171	385	1	molecular	molecular	ADJ
aji-171	385	2	cell	cell	NOUN
aji-171	385	3	endocrinology	endocrinology	NOUN
aji-171	385	4	,	,	PUNCT
aji-171	385	5	301	301	NUM
aji-171	385	6	,	,	PUNCT
aji-171	385	7	266–271	266–271	NUM
aji-171	385	8	.	.	PUNCT
aji-171	386	1	chaurasia	chaurasia	PROPN
aji-171	386	2	,	,	PUNCT
aji-171	386	3	b.	b.	PROPN
aji-171	386	4	,	,	PUNCT
aji-171	386	5	&	&	CCONJ
aji-171	386	6	summers	summers	PROPN
aji-171	386	7	,	,	PUNCT
aji-171	386	8	s.	s.	PROPN
aji-171	386	9	a.	a.	PROPN
aji-171	386	10	(	(	PUNCT
aji-171	386	11	2021	2021	NUM
aji-171	386	12	)	)	PUNCT
aji-171	386	13	.	.	PUNCT
aji-171	387	1	ceramides	ceramide	NOUN
aji-171	387	2	in	in	ADP
aji-171	387	3	metabolism	metabolism	NOUN
aji-171	387	4	:	:	PUNCT
aji-171	387	5	key	key	ADJ
aji-171	387	6	lipotoxic	lipotoxic	ADJ
aji-171	387	7	players	player	NOUN
aji-171	387	8	.	.	PUNCT
aji-171	388	1	annual	annual	ADJ
aji-171	388	2	review	review	NOUN
aji-171	388	3	of	of	ADP
aji-171	388	4	physiology	physiology	NOUN
aji-171	388	5	,	,	PUNCT
aji-171	388	6	83	83	NUM
aji-171	388	7	,	,	PUNCT
aji-171	388	8	303–330	303–330	NUM
aji-171	388	9	.	.	PUNCT
aji-171	389	1	cheng	cheng	PROPN
aji-171	389	2	,	,	PUNCT
aji-171	389	3	s.	s.	PROPN
aji-171	389	4	,	,	PUNCT
aji-171	389	5	rhee	rhee	PROPN
aji-171	389	6	,	,	PUNCT
aji-171	389	7	e.	e.	PROPN
aji-171	389	8	p.	p.	PROPN
aji-171	389	9	,	,	PUNCT
aji-171	389	10	larson	larson	PROPN
aji-171	389	11	,	,	PUNCT
aji-171	389	12	m.	m.	NOUN
aji-171	389	13	g.	g.	PROPN
aji-171	389	14	,	,	PUNCT
aji-171	389	15	lewis	lewis	PROPN
aji-171	389	16	,	,	PUNCT
aji-171	389	17	g.	g.	PROPN
aji-171	389	18	d.	d.	PROPN
aji-171	389	19	,	,	PUNCT
aji-171	389	20	mccabe	mccabe	PROPN
aji-171	389	21	,	,	PUNCT
aji-171	389	22	e.	e.	PROPN
aji-171	389	23	l.	l.	PROPN
aji-171	389	24	,	,	PUNCT
aji-171	389	25	shen	shen	PROPN
aji-171	389	26	,	,	PUNCT
aji-171	389	27	d.	d.	PROPN
aji-171	389	28	,	,	PUNCT
aji-171	389	29	palma	palma	NOUN
aji-171	389	30	,	,	PUNCT
aji-171	389	31	m.	m.	NOUN
aji-171	389	32	j.	j.	PROPN
aji-171	389	33	,	,	PUNCT
aji-171	389	34	roberts	roberts	PROPN
aji-171	389	35	,	,	PUNCT
aji-171	389	36	l.	l.	PROPN
aji-171	389	37	d.	d.	PROPN
aji-171	389	38	,	,	PUNCT
aji-171	389	39	dejam	dejam	PROPN
aji-171	389	40	,	,	PUNCT
aji-171	389	41	a.	a.	PROPN
aji-171	389	42	,	,	PUNCT
aji-171	389	43	&	&	CCONJ
aji-171	389	44	souza	souza	PROPN
aji-171	389	45	,	,	PUNCT
aji-171	389	46	a.	a.	PROPN
aji-171	389	47	l.	l.	PROPN
aji-171	389	48	(	(	PUNCT
aji-171	389	49	2012	2012	NUM
aji-171	389	50	)	)	PUNCT
aji-171	389	51	.	.	PUNCT
aji-171	390	1	metabolite	metabolite	NOUN
aji-171	390	2	profiling	profiling	NOUN
aji-171	390	3	identifies	identify	VERB
aji-171	390	4	pathways	pathway	NOUN
aji-171	390	5	associated	associate	VERB
aji-171	390	6	with	with	ADP
aji-171	390	7	metabolic	metabolic	NOUN
aji-171	390	8	risk	risk	NOUN
aji-171	390	9	in	in	ADP
aji-171	390	10	humans	human	NOUN
aji-171	390	11	.	.	PUNCT
aji-171	391	1	circulation	circulation	NOUN
aji-171	391	2	,	,	PUNCT
aji-171	391	3	125	125	NUM
aji-171	391	4	,	,	PUNCT
aji-171	391	5	2222–2231	2222–2231	NUM
aji-171	391	6	.	.	PUNCT
aji-171	392	1	collins	collins	PROPN
aji-171	392	2	,	,	PUNCT
aji-171	392	3	r.	r.	PROPN
aji-171	392	4	r.	r.	PROPN
aji-171	392	5	,	,	PUNCT
aji-171	392	6	patel	patel	PROPN
aji-171	392	7	,	,	PUNCT
aji-171	392	8	k.	k.	PROPN
aji-171	392	9	,	,	PUNCT
aji-171	392	10	putnam	putnam	PROPN
aji-171	392	11	,	,	PUNCT
aji-171	392	12	w.	w.	PROPN
aji-171	392	13	c.	c.	PROPN
aji-171	392	14	,	,	PUNCT
aji-171	392	15	kapur	kapur	PROPN
aji-171	392	16	,	,	PUNCT
aji-171	392	17	p.	p.	PROPN
aji-171	392	18	,	,	PUNCT
aji-171	392	19	&	&	CCONJ
aji-171	392	20	rakheja	rakheja	PROPN
aji-171	392	21	,	,	PUNCT
aji-171	392	22	d.	d.	PROPN
aji-171	392	23	(	(	PUNCT
aji-171	392	24	2017	2017	NUM
aji-171	392	25	)	)	PUNCT
aji-171	392	26	.	.	PUNCT
aji-171	393	1	oncometabolites	oncometabolite	NOUN
aji-171	393	2	:	:	PUNCT
aji-171	393	3	new	new	ADJ
aji-171	393	4	paradigm	paradigm	NOUN
aji-171	393	5	for	for	ADP
aji-171	393	6	oncology	oncology	NOUN
aji-171	393	7	,	,	PUNCT
aji-171	393	8	metabolism	metabolism	NOUN
aji-171	393	9	,	,	PUNCT
aji-171	393	10	and	and	CCONJ
aji-171	393	11	the	the	DET
aji-171	393	12	clinical	clinical	ADJ
aji-171	393	13	laboratory	laboratory	NOUN
aji-171	393	14	.	.	PUNCT
aji-171	394	1	clinical	clinical	ADJ
aji-171	394	2	chemistry	chemistry	NOUN
aji-171	394	3	,	,	PUNCT
aji-171	394	4	63	63	NUM
aji-171	394	5	,	,	PUNCT
aji-171	394	6	1812	1812	NUM
aji-171	394	7	–	–	PUNCT
aji-171	394	8	1820	1820	NUM
aji-171	394	9	.	.	PUNCT
aji-171	395	1	dalamaga	dalamaga	NOUN
aji-171	395	2	,	,	PUNCT
aji-171	395	3	m.	m.	NOUN
aji-171	395	4	(	(	PUNCT
aji-171	395	5	2024	2024	NUM
aji-171	395	6	)	)	PUNCT
aji-171	395	7	.	.	PUNCT
aji-171	396	1	clinical	clinical	ADJ
aji-171	396	2	metabolomics	metabolomic	NOUN
aji-171	396	3	:	:	PUNCT
aji-171	396	4	useful	useful	ADJ
aji-171	396	5	insights	insight	NOUN
aji-171	396	6	,	,	PUNCT
aji-171	396	7	perspectives	perspective	NOUN
aji-171	396	8	and	and	CCONJ
aji-171	396	9	challenges	challenge	NOUN
aji-171	396	10	.	.	PUNCT
aji-171	397	1	metabolism	metabolism	NOUN
aji-171	397	2	,	,	PUNCT
aji-171	397	3	22	22	NUM
aji-171	397	4	,	,	PUNCT
aji-171	397	5	100290	100290	NUM
aji-171	397	6	.	.	PUNCT
aji-171	398	1	dalla	dalla	PROPN
aji-171	398	2	pozza	pozza	PROPN
aji-171	398	3	,	,	PUNCT
aji-171	398	4	e.	e.	PROPN
aji-171	398	5	,	,	PUNCT
aji-171	398	6	dando	dando	PROPN
aji-171	398	7	,	,	PUNCT
aji-171	398	8	i.	i.	PROPN
aji-171	398	9	,	,	PUNCT
aji-171	398	10	pacchiana	pacchiana	PROPN
aji-171	398	11	,	,	PUNCT
aji-171	398	12	r.	r.	PROPN
aji-171	398	13	,	,	PUNCT
aji-171	398	14	liboi	liboi	PROPN
aji-171	398	15	,	,	PUNCT
aji-171	398	16	e.	e.	PROPN
aji-171	398	17	,	,	PUNCT
aji-171	398	18	scupoli	scupoli	PROPN
aji-171	398	19	,	,	PUNCT
aji-171	398	20	m.	m.	NOUN
aji-171	398	21	t.	t.	PROPN
aji-171	398	22	,	,	PUNCT
aji-171	398	23	donadelli	donadelli	PROPN
aji-171	398	24	,	,	PUNCT
aji-171	398	25	m.	m.	NOUN
aji-171	398	26	,	,	PUNCT
aji-171	398	27	&	&	CCONJ
aji-171	398	28	palmieri	palmieri	PROPN
aji-171	398	29	,	,	PUNCT
aji-171	398	30	m.	m.	NOUN
aji-171	398	31	(	(	PUNCT
aji-171	398	32	2020	2020	NUM
aji-171	398	33	)	)	PUNCT
aji-171	398	34	.	.	PUNCT
aji-171	399	1	regulation	regulation	NOUN
aji-171	399	2	of	of	ADP
aji-171	399	3	succinate	succinate	NOUN
aji-171	399	4	dehydrogenase	dehydrogenase	NOUN
aji-171	399	5	and	and	CCONJ
aji-171	399	6	role	role	NOUN
aji-171	399	7	of	of	ADP
aji-171	399	8	succinate	succinate	NOUN
aji-171	399	9	in	in	ADP
aji-171	399	10	cancer	cancer	NOUN
aji-171	399	11	.	.	PUNCT
aji-171	400	1	seminars	seminar	NOUN
aji-171	400	2	in	in	ADP
aji-171	400	3	cell	cell	NOUN
aji-171	400	4	and	and	CCONJ
aji-171	400	5	developmental	developmental	ADJ
aji-171	400	6	biology	biology	NOUN
aji-171	400	7	journsal	journsal	NOUN
aji-171	400	8	,	,	PUNCT
aji-171	400	9	98	98	NUM
aji-171	400	10	,	,	PUNCT
aji-171	400	11	4–14	4–14	PROPN
aji-171	400	12	.	.	PUNCT
aji-171	401	1	damiani	damiani	PROPN
aji-171	401	2	,	,	PUNCT
aji-171	401	3	c.	c.	PROPN
aji-171	401	4	,	,	PUNCT
aji-171	401	5	gaglio	gaglio	NOUN
aji-171	401	6	,	,	PUNCT
aji-171	401	7	d.	d.	PROPN
aji-171	401	8	,	,	PUNCT
aji-171	401	9	sacco	sacco	PROPN
aji-171	401	10	,	,	PUNCT
aji-171	401	11	e.	e.	PROPN
aji-171	401	12	,	,	PUNCT
aji-171	401	13	alberghina	alberghina	PROPN
aji-171	401	14	,	,	PUNCT
aji-171	401	15	l.	l.	PROPN
aji-171	401	16	,	,	PUNCT
aji-171	401	17	&	&	CCONJ
aji-171	401	18	vanoni	vanoni	NOUN
aji-171	401	19	,	,	PUNCT
aji-171	401	20	m.	m.	NOUN
aji-171	401	21	(	(	PUNCT
aji-171	401	22	2020	2020	NUM
aji-171	401	23	)	)	PUNCT
aji-171	401	24	.	.	PUNCT
aji-171	402	1	systems	system	NOUN
aji-171	402	2	metabolomics	metabolomic	NOUN
aji-171	402	3	:	:	PUNCT
aji-171	402	4	from	from	ADP
aji-171	402	5	metabolomic	metabolomic	ADJ
aji-171	402	6	snapshots	snapshot	NOUN
aji-171	402	7	to	to	PART
aji-171	402	8	design	design	VERB
aji-171	402	9	principles	principle	NOUN
aji-171	402	10	.	.	PUNCT
aji-171	403	1	current	current	ADJ
aji-171	403	2	opinion	opinion	NOUN
aji-171	403	3	in	in	ADP
aji-171	403	4	biotechnology	biotechnology	NOUN
aji-171	403	5	journal	journal	NOUN
aji-171	403	6	,	,	PUNCT
aji-171	403	7	63	63	NUM
aji-171	403	8	,	,	PUNCT
aji-171	403	9	190	190	NUM
aji-171	403	10	–	–	SYM
aji-171	403	11	199	199	NUM
aji-171	403	12	.	.	PUNCT
aji-171	403	13	deberardinis	deberardinis	PROPN
aji-171	403	14	,	,	PUNCT
aji-171	403	15	r.	r.	PROPN
aji-171	403	16	j.	j.	PROPN
aji-171	403	17	,	,	PUNCT
aji-171	403	18	&	&	CCONJ
aji-171	403	19	chandel	chandel	PROPN
aji-171	403	20	,	,	PUNCT
aji-171	403	21	n.	n.	PROPN
aji-171	403	22	s.	s.	PROPN
aji-171	403	23	(	(	PUNCT
aji-171	403	24	2020	2020	NUM
aji-171	403	25	)	)	PUNCT
aji-171	403	26	.	.	PUNCT
aji-171	404	1	we	we	PRON
aji-171	404	2	need	need	VERB
aji-171	404	3	to	to	PART
aji-171	404	4	talk	talk	VERB
aji-171	404	5	about	about	ADP
aji-171	404	6	the	the	DET
aji-171	404	7	warburg	warburg	NOUN
aji-171	404	8	effect	effect	NOUN
aji-171	404	9	.	.	PUNCT
aji-171	405	1	nature	nature	NOUN
aji-171	405	2	of	of	ADP
aji-171	405	3	metabolism	metabolism	NOUN
aji-171	405	4	,	,	PUNCT
aji-171	405	5	2	2	NUM
aji-171	405	6	,	,	PUNCT
aji-171	405	7	127–129	127–129	NUM
aji-171	405	8	.	.	PUNCT
aji-171	406	1	deng	deng	PROPN
aji-171	406	2	,	,	PUNCT
aji-171	406	3	x.	x.	PROPN
aji-171	406	4	,	,	PUNCT
aji-171	406	5	saffari	saffari	PROPN
aji-171	406	6	,	,	PUNCT
aji-171	406	7	s.	s.	PROPN
aji-171	406	8	e.	e.	PROPN
aji-171	406	9	,	,	PUNCT
aji-171	406	10	liu	liu	PROPN
aji-171	406	11	,	,	PUNCT
aji-171	406	12	n.	n.	PROPN
aji-171	406	13	,	,	PUNCT
aji-171	406	14	xiao	xiao	PROPN
aji-171	406	15	,	,	PUNCT
aji-171	406	16	b.	b.	PROPN
aji-171	406	17	,	,	PUNCT
aji-171	406	18	allen	allen	PROPN
aji-171	406	19	,	,	PUNCT
aji-171	406	20	j.	j.	PROPN
aji-171	406	21	c.	c.	PROPN
aji-171	406	22	,	,	PUNCT
aji-171	406	23	ng	ng	PROPN
aji-171	406	24	,	,	PUNCT
aji-171	406	25	s.	s.	PROPN
aji-171	406	26	y.	y.	PROPN
aji-171	406	27	e.	e.	PROPN
aji-171	406	28	,	,	PUNCT
aji-171	406	29	chia	chia	PROPN
aji-171	406	30	,	,	PUNCT
aji-171	406	31	n.	n.	PROPN
aji-171	406	32	,	,	PUNCT
aji-171	406	33	tan	tan	PROPN
aji-171	406	34	,	,	PUNCT
aji-171	406	35	y.	y.	PROPN
aji-171	406	36	j.	j.	PROPN
aji-171	406	37	,	,	PUNCT
aji-171	406	38	choi	choi	NOUN
aji-171	406	39	,	,	PUNCT
aji-171	406	40	x.	x.	PROPN
aji-171	406	41	,	,	PUNCT
aji-171	406	42	&	&	CCONJ
aji-171	406	43	heng	heng	PROPN
aji-171	406	44	,	,	PUNCT
aji-171	406	45	d.	d.	PROPN
aji-171	406	46	l.	l.	PROPN
aji-171	406	47	(	(	PUNCT
aji-171	406	48	2022	2022	NUM
aji-171	406	49	)	)	PUNCT
aji-171	406	50	.	.	PUNCT
aji-171	407	1	biomarker	biomarker	NOUN
aji-171	407	2	characterization	characterization	NOUN
aji-171	407	3	of	of	ADP
aji-171	407	4	clinical	clinical	ADJ
aji-171	407	5	subtypes	subtype	NOUN
aji-171	407	6	of	of	ADP
aji-171	407	7	parkinson	parkinson	NOUN
aji-171	407	8	disease	disease	NOUN
aji-171	407	9	.	.	PUNCT
aji-171	408	1	npj	npj	PROPN
aji-171	408	2	parkinson	parkinson	NOUN
aji-171	408	3	disease	disease	NOUN
aji-171	408	4	,	,	PUNCT
aji-171	408	5	8	8	NUM
aji-171	408	6	,	,	PUNCT
aji-171	408	7	109	109	NUM
aji-171	408	8	.	.	PUNCT
aji-171	408	9	di	di	PROPN
aji-171	408	10	gregorio	gregorio	PROPN
aji-171	408	11	,	,	PUNCT
aji-171	408	12	e.	e.	PROPN
aji-171	408	13	,	,	PUNCT
aji-171	408	14	miolo	miolo	ADV
aji-171	408	15	,	,	PUNCT
aji-171	408	16	g.	g.	PROPN
aji-171	408	17	,	,	PUNCT
aji-171	408	18	saorin	saorin	NOUN
aji-171	408	19	,	,	PUNCT
aji-171	408	20	a.	a.	NOUN
aji-171	408	21	,	,	PUNCT
aji-171	408	22	steffan	steffan	PROPN
aji-171	408	23	,	,	PUNCT
aji-171	408	24	a.	a.	PROPN
aji-171	408	25	,	,	PUNCT
aji-171	408	26	&	&	CCONJ
aji-171	408	27	corona	corona	PROPN
aji-171	408	28	,	,	PUNCT
aji-171	408	29	g.	g.	PROPN
aji-171	408	30	(	(	PUNCT
aji-171	408	31	2021	2021	NUM
aji-171	408	32	)	)	PUNCT
aji-171	408	33	.	.	PUNCT
aji-171	409	1	from	from	ADP
aji-171	409	2	metabolism	metabolism	NOUN
aji-171	409	3	to	to	ADP
aji-171	409	4	genetics	genetic	NOUN
aji-171	409	5	and	and	CCONJ
aji-171	409	6	vice	vice	NOUN
aji-171	409	7	versa	versa	ADV
aji-171	409	8	:	:	PUNCT
aji-171	409	9	the	the	DET
aji-171	409	10	rising	rise	VERB
aji-171	409	11	role	role	NOUN
aji-171	409	12	of	of	ADP
aji-171	409	13	oncometabolites	oncometabolite	NOUN
aji-171	409	14	in	in	ADP
aji-171	409	15	cancer	cancer	NOUN
aji-171	409	16	development	development	NOUN
aji-171	409	17	and	and	CCONJ
aji-171	409	18	therapy	therapy	NOUN
aji-171	409	19	.	.	PUNCT
aji-171	410	1	international	international	ADJ
aji-171	410	2	journal	journal	NOUN
aji-171	410	3	of	of	ADP
aji-171	410	4	molecular	molecular	ADJ
aji-171	410	5	science	science	NOUN
aji-171	410	6	,	,	PUNCT
aji-171	410	7	22	22	NUM
aji-171	410	8	,	,	PUNCT
aji-171	410	9	5574	5574	NUM
aji-171	410	10	.	.	PUNCT
aji-171	411	1	dinardo	dinardo	PROPN
aji-171	411	2	,	,	PUNCT
aji-171	411	3	c.	c.	PROPN
aji-171	411	4	d.	d.	PROPN
aji-171	411	5	,	,	PUNCT
aji-171	411	6	propert	propert	PROPN
aji-171	411	7	,	,	PUNCT
aji-171	411	8	k.	k.	PROPN
aji-171	411	9	j.	j.	PROPN
aji-171	411	10	,	,	PUNCT
aji-171	411	11	loren	loren	PROPN
aji-171	411	12	,	,	PUNCT
aji-171	411	13	a.	a.	PROPN
aji-171	411	14	w.	w.	PROPN
aji-171	411	15	,	,	PUNCT
aji-171	411	16	paietta	paietta	PROPN
aji-171	411	17	,	,	PUNCT
aji-171	411	18	e.	e.	PROPN
aji-171	411	19	,	,	PUNCT
aji-171	411	20	sun	sun	PROPN
aji-171	411	21	,	,	PUNCT
aji-171	411	22	z.	z.	PROPN
aji-171	411	23	,	,	PUNCT
aji-171	411	24	levine	levine	PROPN
aji-171	411	25	,	,	PUNCT
aji-171	411	26	r.	r.	PROPN
aji-171	411	27	l.	l.	PROPN
aji-171	411	28	,	,	PUNCT
aji-171	411	29	straley	straley	PROPN
aji-171	411	30	,	,	PUNCT
aji-171	411	31	k.	k.	PROPN
aji-171	411	32	s.	s.	PROPN
aji-171	411	33	,	,	PUNCT
aji-171	411	34	yen	yen	NOUN
aji-171	411	35	,	,	PUNCT
aji-171	411	36	k.	k.	PROPN
aji-171	411	37	,	,	PUNCT
aji-171	411	38	patel	patel	PROPN
aji-171	411	39	,	,	PUNCT
aji-171	411	40	j.	j.	PROPN
aji-171	411	41	p.	p.	PROPN
aji-171	411	42	,	,	PUNCT
aji-171	411	43	&	&	CCONJ
aji-171	411	44	agresta	agresta	PROPN
aji-171	411	45	,	,	PUNCT
aji-171	411	46	s.	s.	PROPN
aji-171	411	47	(	(	PUNCT
aji-171	411	48	2013	2013	NUM
aji-171	411	49	)	)	PUNCT
aji-171	411	50	.	.	PUNCT
aji-171	412	1	serum	serum	PROPN
aji-171	412	2	2	2	NUM
aji-171	412	3	-	-	PUNCT
aji-171	412	4	hydroxyglutarate	hydroxyglutarate	NOUN
aji-171	412	5	levels	level	NOUN
aji-171	412	6	predict	predict	VERB
aji-171	412	7	isocitrate	isocitrate	ADJ
aji-171	412	8	dehydrogenase	dehydrogenase	NOUN
aji-171	412	9	mutations	mutation	NOUN
aji-171	412	10	and	and	CCONJ
aji-171	412	11	clinical	clinical	ADJ
aji-171	412	12	outcome	outcome	NOUN
aji-171	412	13	in	in	ADP
aji-171	412	14	acute	acute	ADJ
aji-171	412	15	myeloid	myeloid	ADJ
aji-171	412	16	leukemia	leukemia	NOUN
aji-171	412	17	.	.	PUNCT
aji-171	413	1	blood	blood	NOUN
aji-171	413	2	journal	journal	PROPN
aji-171	413	3	of	of	ADP
aji-171	413	4	american	american	ADJ
aji-171	413	5	society	society	NOUN
aji-171	413	6	of	of	ADP
aji-171	413	7	hematology	hematology	NOUN
aji-171	413	8	,	,	PUNCT
aji-171	413	9	121	121	NUM
aji-171	413	10	,	,	PUNCT
aji-171	413	11	4917–4924	4917–4924	NUM
aji-171	413	12	.	.	PUNCT
aji-171	414	1	doestzada	doestzada	PROPN
aji-171	414	2	,	,	PUNCT
aji-171	414	3	m.	m.	NOUN
aji-171	414	4	,	,	PUNCT
aji-171	414	5	zhernakova	zhernakova	PROPN
aji-171	414	6	,	,	PUNCT
aji-171	414	7	d.	d.	PROPN
aji-171	414	8	v.	v.	PROPN
aji-171	414	9	,	,	PUNCT
aji-171	414	10	van	van	PROPN
aji-171	414	11	den	den	PROPN
aji-171	414	12	munckhof	munckhof	PROPN
aji-171	414	13	,	,	PUNCT
aji-171	414	14	c.	c.	PROPN
aji-171	414	15	l.	l.	PROPN
aji-171	414	16	i.	i.	PROPN
aji-171	414	17	,	,	PUNCT
aji-171	414	18	wang	wang	PROPN
aji-171	414	19	,	,	PUNCT
aji-171	414	20	d.	d.	PROPN
aji-171	414	21	,	,	PUNCT
aji-171	414	22	kurilshikov	kurilshikov	PROPN
aji-171	414	23	,	,	PUNCT
aji-171	414	24	a.	a.	PROPN
aji-171	414	25	,	,	PUNCT
aji-171	414	26	chen	chen	PROPN
aji-171	414	27	,	,	PUNCT
aji-171	414	28	l.	l.	PROPN
aji-171	414	29	,	,	PUNCT
aji-171	414	30	bloks	bloks	PROPN
aji-171	414	31	,	,	PUNCT
aji-171	414	32	v.	v.	PROPN
aji-171	414	33	w.	w.	PROPN
aji-171	414	34	,	,	PUNCT
aji-171	414	35	van	van	PROPN
aji-171	414	36	faassen	faassen	NOUN
aji-171	414	37	,	,	PUNCT
aji-171	414	38	m.	m.	NOUN
aji-171	414	39	,	,	PUNCT
aji-171	414	40	rutten	rutten	PROPN
aji-171	414	41	,	,	PUNCT
aji-171	414	42	j.	j.	PROPN
aji-171	414	43	h.	h.	PROPN
aji-171	414	44	,	,	PUNCT
aji-171	414	45	&	&	CCONJ
aji-171	414	46	joosten	joosten	VERB
aji-171	414	47	,	,	PUNCT
aji-171	414	48	l.	l.	PROPN
aji-171	414	49	a.	a.	PROPN
aji-171	414	50	(	(	PUNCT
aji-171	414	51	2022	2022	NUM
aji-171	414	52	)	)	PUNCT
aji-171	414	53	.	.	PUNCT
aji-171	415	1	systematic	systematic	ADJ
aji-171	415	2	analysis	analysis	NOUN
aji-171	415	3	of	of	ADP
aji-171	415	4	relationships	relationship	NOUN
aji-171	415	5	between	between	ADP
aji-171	415	6	plasma	plasma	NOUN
aji-171	415	7	branched	branch	VERB
aji-171	415	8	-	-	PUNCT
aji-171	415	9	chain	chain	NOUN
aji-171	415	10	amino	amino	NOUN
aji-171	415	11	acid	acid	NOUN
aji-171	415	12	concentrations	concentration	NOUN
aji-171	415	13	and	and	CCONJ
aji-171	415	14	cardiometabolic	cardiometabolic	NOUN
aji-171	415	15	parameters	parameter	NOUN
aji-171	415	16	:	:	PUNCT
aji-171	415	17	an	an	DET
aji-171	415	18	association	association	NOUN
aji-171	415	19	and	and	CCONJ
aji-171	415	20	mendelian	mendelian	ADJ
aji-171	415	21	randomization	randomization	NOUN
aji-171	415	22	study	study	NOUN
aji-171	415	23	.	.	PUNCT
aji-171	416	1	bmc	bmc	PROPN
aji-171	416	2	medical	medical	ADJ
aji-171	416	3	,	,	PUNCT
aji-171	416	4	20	20	NUM
aji-171	416	5	,	,	PUNCT
aji-171	416	6	485	485	NUM
aji-171	416	7	.	.	PUNCT
aji-171	417	1	mamman	mamman	NOUN
aji-171	417	2	et	et	PROPN
aji-171	417	3	al	al	PROPN
aji-171	417	4	.	.	PROPN
aji-171	417	5	;	;	PUNCT
aji-171	417	6	asian	asian	PROPN
aji-171	417	7	j.	j.	PROPN
aji-171	417	8	immunol	immunol	PROPN
aji-171	417	9	.	.	PROPN
aji-171	417	10	,	,	PUNCT
aji-171	417	11	vol	vol	NOUN
aji-171	417	12	.	.	PROPN
aji-171	417	13	8	8	NUM
aji-171	417	14	,	,	PUNCT
aji-171	417	15	no	no	INTJ
aji-171	417	16	.	.	NOUN
aji-171	417	17	1	1	NUM
aji-171	417	18	,	,	PUNCT
aji-171	417	19	pp	pp	ADJ
aji-171	417	20	.	.	PUNCT
aji-171	418	1	190	190	NUM
aji-171	418	2	-	-	SYM
aji-171	418	3	206	206	NUM
aji-171	418	4	,	,	PUNCT
aji-171	418	5	2025	2025	NUM
aji-171	418	6	;	;	PUNCT
aji-171	418	7	article	article	NOUN
aji-171	418	8	no.aji.140476	no.aji.140476	PROPN
aji-171	418	9	202	202	NUM
aji-171	418	10	dubois	dubois	PROPN
aji-171	418	11	,	,	PUNCT
aji-171	418	12	b.	b.	PROPN
aji-171	418	13	,	,	PUNCT
aji-171	418	14	von	von	PROPN
aji-171	418	15	arnim	arnim	PROPN
aji-171	418	16	,	,	PUNCT
aji-171	418	17	c.	c.	PROPN
aji-171	418	18	a.	a.	PROPN
aji-171	418	19	,	,	PUNCT
aji-171	418	20	burnie	burnie	PROPN
aji-171	418	21	,	,	PUNCT
aji-171	418	22	n.	n.	NOUN
aji-171	418	23	,	,	PUNCT
aji-171	418	24	bozeat	bozeat	NOUN
aji-171	418	25	,	,	PUNCT
aji-171	418	26	s.	s.	PROPN
aji-171	418	27	,	,	PUNCT
aji-171	418	28	&	&	CCONJ
aji-171	418	29	cummings	cummings	PROPN
aji-171	418	30	,	,	PUNCT
aji-171	418	31	j.	j.	PROPN
aji-171	418	32	(	(	PUNCT
aji-171	418	33	2023	2023	NUM
aji-171	418	34	)	)	PUNCT
aji-171	418	35	.	.	PUNCT
aji-171	419	1	biomarkers	biomarker	NOUN
aji-171	419	2	in	in	ADP
aji-171	419	3	alzheimer	alzheimer	PROPN
aji-171	419	4	’s	’s	PART
aji-171	419	5	disease	disease	NOUN
aji-171	419	6	:	:	PUNCT
aji-171	419	7	role	role	NOUN
aji-171	419	8	in	in	ADP
aji-171	419	9	early	early	ADJ
aji-171	419	10	and	and	CCONJ
aji-171	419	11	differential	differential	ADJ
aji-171	419	12	diagnosis	diagnosis	NOUN
aji-171	419	13	and	and	CCONJ
aji-171	419	14	recognition	recognition	NOUN
aji-171	419	15	of	of	ADP
aji-171	419	16	atypical	atypical	ADJ
aji-171	419	17	variants	variant	NOUN
aji-171	419	18	.	.	PUNCT
aji-171	420	1	alzheimer	alzheimer	PROPN
aji-171	420	2	’s	’s	PART
aji-171	420	3	research	research	NOUN
aji-171	420	4	and	and	CCONJ
aji-171	420	5	therapy	therapy	NOUN
aji-171	420	6	,	,	PUNCT
aji-171	420	7	15	15	NUM
aji-171	420	8	,	,	PUNCT
aji-171	420	9	175	175	NUM
aji-171	420	10	.	.	PUNCT
aji-171	421	1	fandrey	fandrey	PROPN
aji-171	421	2	,	,	PUNCT
aji-171	421	3	j.	j.	PROPN
aji-171	421	4	,	,	PUNCT
aji-171	421	5	schödel	schödel	PROPN
aji-171	421	6	,	,	PUNCT
aji-171	421	7	j.	j.	PROPN
aji-171	421	8	,	,	PUNCT
aji-171	421	9	eckardt	eckardt	NOUN
aji-171	421	10	,	,	PUNCT
aji-171	421	11	k.	k.	PROPN
aji-171	421	12	u.	u.	PROPN
aji-171	421	13	,	,	PUNCT
aji-171	421	14	katschinski	katschinski	PROPN
aji-171	421	15	,	,	PUNCT
aji-171	421	16	d.	d.	PROPN
aji-171	421	17	m.	m.	PROPN
aji-171	421	18	,	,	PUNCT
aji-171	421	19	&	&	CCONJ
aji-171	421	20	wenger	wenger	PROPN
aji-171	421	21	,	,	PUNCT
aji-171	421	22	r.	r.	PROPN
aji-171	421	23	h.	h.	PROPN
aji-171	421	24	(	(	PUNCT
aji-171	421	25	2019	2019	NUM
aji-171	421	26	)	)	PUNCT
aji-171	421	27	.	.	PUNCT
aji-171	422	1	now	now	ADV
aji-171	422	2	a	a	DET
aji-171	422	3	nobel	nobel	PROPN
aji-171	422	4	gas	gas	NOUN
aji-171	422	5	:	:	PUNCT
aji-171	422	6	oxygen	oxygen	NOUN
aji-171	422	7	.	.	PUNCT
aji-171	423	1	pflügers	pflüger	NOUN
aji-171	423	2	archiv	archiv	PROPN
aji-171	423	3	european	european	PROPN
aji-171	423	4	journal	journal	PROPN
aji-171	423	5	of	of	ADP
aji-171	423	6	physiology	physiology	NOUN
aji-171	423	7	,	,	PUNCT
aji-171	423	8	471	471	NUM
aji-171	423	9	,	,	PUNCT
aji-171	423	10	1343–1358	1343–1358	NUM
aji-171	423	11	.	.	PUNCT
aji-171	424	1	ganguly	ganguly	PROPN
aji-171	424	2	,	,	PUNCT
aji-171	424	3	u.	u.	PROPN
aji-171	424	4	,	,	PUNCT
aji-171	424	5	singh	singh	PROPN
aji-171	424	6	,	,	PUNCT
aji-171	424	7	s.	s.	PROPN
aji-171	424	8	,	,	PUNCT
aji-171	424	9	pal	pal	NOUN
aji-171	424	10	,	,	PUNCT
aji-171	424	11	s.	s.	PROPN
aji-171	424	12	,	,	PUNCT
aji-171	424	13	prasad	prasad	PROPN
aji-171	424	14	,	,	PUNCT
aji-171	424	15	s.	s.	PROPN
aji-171	424	16	,	,	PUNCT
aji-171	424	17	agrawal	agrawal	PROPN
aji-171	424	18	,	,	PUNCT
aji-171	424	19	b.	b.	PROPN
aji-171	424	20	k.	k.	PROPN
aji-171	424	21	,	,	PUNCT
aji-171	424	22	saini	saini	PROPN
aji-171	424	23	,	,	PUNCT
aji-171	424	24	r.	r.	PROPN
aji-171	424	25	v.	v.	PROPN
aji-171	424	26	,	,	PUNCT
aji-171	424	27	&	&	CCONJ
aji-171	424	28	chakrabarti	chakrabarti	PROPN
aji-171	424	29	,	,	PUNCT
aji-171	424	30	s.	s.	PROPN
aji-171	424	31	(	(	PUNCT
aji-171	424	32	2021	2021	NUM
aji-171	424	33	)	)	PUNCT
aji-171	424	34	.	.	PUNCT
aji-171	425	1	alpha	alpha	NOUN
aji-171	425	2	-	-	PUNCT
aji-171	425	3	synuclein	synuclein	NOUN
aji-171	425	4	as	as	ADP
aji-171	425	5	a	a	DET
aji-171	425	6	biomarker	biomarker	NOUN
aji-171	425	7	of	of	ADP
aji-171	425	8	parkinson	parkinson	NOUN
aji-171	425	9	’s	’s	PART
aji-171	425	10	disease	disease	NOUN
aji-171	425	11	:	:	PUNCT
aji-171	425	12	good	good	ADJ
aji-171	425	13	,	,	PUNCT
aji-171	425	14	but	but	CCONJ
aji-171	425	15	not	not	PART
aji-171	425	16	good	good	ADJ
aji-171	425	17	enough	enough	ADV
aji-171	425	18	.	.	PUNCT
aji-171	426	1	frontiers	frontier	NOUN
aji-171	426	2	in	in	ADP
aji-171	426	3	aging	age	VERB
aji-171	426	4	neuroscience	neuroscience	NOUN
aji-171	426	5	,	,	PUNCT
aji-171	426	6	13	13	NUM
aji-171	426	7	,	,	PUNCT
aji-171	426	8	702639	702639	NUM
aji-171	426	9	.	.	PUNCT
aji-171	427	1	gar	gar	PROPN
aji-171	427	2	,	,	PUNCT
aji-171	427	3	c.	c.	PROPN
aji-171	427	4	,	,	PUNCT
aji-171	427	5	rottenkolber	rottenkolber	PROPN
aji-171	427	6	,	,	PUNCT
aji-171	427	7	m.	m.	NOUN
aji-171	427	8	,	,	PUNCT
aji-171	427	9	prehn	prehn	PROPN
aji-171	427	10	,	,	PUNCT
aji-171	427	11	c.	c.	PROPN
aji-171	427	12	,	,	PUNCT
aji-171	427	13	adamski	adamski	PROPN
aji-171	427	14	,	,	PUNCT
aji-171	427	15	j.	j.	PROPN
aji-171	427	16	,	,	PUNCT
aji-171	427	17	seissler	seissler	NOUN
aji-171	427	18	,	,	PUNCT
aji-171	427	19	j.	j.	PROPN
aji-171	427	20	,	,	PUNCT
aji-171	427	21	&	&	CCONJ
aji-171	427	22	lechner	lechner	PROPN
aji-171	427	23	,	,	PUNCT
aji-171	427	24	a.	a.	NOUN
aji-171	427	25	(	(	PUNCT
aji-171	427	26	2018	2018	NUM
aji-171	427	27	)	)	PUNCT
aji-171	427	28	.	.	PUNCT
aji-171	428	1	serum	serum	NOUN
aji-171	428	2	and	and	CCONJ
aji-171	428	3	plasma	plasma	NOUN
aji-171	428	4	amino	amino	NOUN
aji-171	428	5	acids	acid	NOUN
aji-171	428	6	as	as	ADP
aji-171	428	7	markers	marker	NOUN
aji-171	428	8	of	of	ADP
aji-171	428	9	prediabetes	prediabete	NOUN
aji-171	428	10	,	,	PUNCT
aji-171	428	11	insulin	insulin	NOUN
aji-171	428	12	resistance	resistance	NOUN
aji-171	428	13	,	,	PUNCT
aji-171	428	14	and	and	CCONJ
aji-171	428	15	incident	incident	NOUN
aji-171	428	16	diabetes	diabete	NOUN
aji-171	428	17	.	.	PUNCT
aji-171	429	1	critical	critical	ADJ
aji-171	429	2	review	review	NOUN
aji-171	429	3	in	in	ADP
aji-171	429	4	clinical	clinical	ADJ
aji-171	429	5	laboratory	laboratory	NOUN
aji-171	429	6	sciences	science	NOUN
aji-171	429	7	,	,	PUNCT
aji-171	429	8	55	55	NUM
aji-171	429	9	.	.	PUNCT
aji-171	430	1	góralczyk	góralczyk	NOUN
aji-171	430	2	-	-	PUNCT
aji-171	430	3	binkowska	binkowska	ADJ
aji-171	430	4	,	,	PUNCT
aji-171	430	5	a.	a.	NOUN
aji-171	430	6	,	,	PUNCT
aji-171	430	7	szmajda	szmajda	NOUN
aji-171	430	8	-	-	PUNCT
aji-171	430	9	krygier	krygier	NOUN
aji-171	430	10	,	,	PUNCT
aji-171	430	11	d.	d.	PROPN
aji-171	430	12	,	,	PUNCT
aji-171	430	13	&	&	CCONJ
aji-171	430	14	kozłowska	kozłowska	PROPN
aji-171	430	15	,	,	PUNCT
aji-171	430	16	e.	e.	PROPN
aji-171	430	17	(	(	PUNCT
aji-171	430	18	2022	2022	NUM
aji-171	430	19	)	)	PUNCT
aji-171	430	20	.	.	PUNCT
aji-171	431	1	the	the	DET
aji-171	431	2	microbiota	microbiota	NOUN
aji-171	431	3	gutbrain	gutbrain	NOUN
aji-171	431	4	axis	axis	NOUN
aji-171	431	5	in	in	ADP
aji-171	431	6	psychiatric	psychiatric	ADJ
aji-171	431	7	disorders	disorder	NOUN
aji-171	431	8	.	.	PUNCT
aji-171	432	1	international	international	ADJ
aji-171	432	2	journal	journal	NOUN
aji-171	432	3	of	of	ADP
aji-171	432	4	molecular	molecular	ADJ
aji-171	432	5	sciences	science	NOUN
aji-171	432	6	,	,	PUNCT
aji-171	432	7	23	23	NUM
aji-171	432	8	,	,	PUNCT
aji-171	432	9	11245	11245	NUM
aji-171	432	10	.	.	PUNCT
aji-171	433	1	guo	guo	PROPN
aji-171	433	2	,	,	PUNCT
aji-171	433	3	s.	s.	PROPN
aji-171	433	4	,	,	PUNCT
aji-171	433	5	zhang	zhang	PROPN
aji-171	433	6	,	,	PUNCT
aji-171	433	7	s.	s.	PROPN
aji-171	433	8	,	,	PUNCT
aji-171	433	9	zhuang	zhuang	PROPN
aji-171	433	10	,	,	PUNCT
aji-171	433	11	y.	y.	PROPN
aji-171	433	12	,	,	PUNCT
aji-171	433	13	xie	xie	PROPN
aji-171	433	14	,	,	PUNCT
aji-171	433	15	f.	f.	PROPN
aji-171	433	16	,	,	PUNCT
aji-171	433	17	wang	wang	PROPN
aji-171	433	18	,	,	PUNCT
aji-171	433	19	r.	r.	PROPN
aji-171	433	20	,	,	PUNCT
aji-171	433	21	&	&	CCONJ
aji-171	433	22	kong	kong	PROPN
aji-171	433	23	,	,	PUNCT
aji-171	433	24	x.	x.	NOUN
aji-171	433	25	(	(	PUNCT
aji-171	433	26	2023	2023	NUM
aji-171	433	27	)	)	PUNCT
aji-171	433	28	.	.	PUNCT
aji-171	434	1	muscle	muscle	NOUN
aji-171	434	2	parp1	parp1	NOUN
aji-171	434	3	inhibition	inhibition	NOUN
aji-171	434	4	extends	extend	VERB
aji-171	434	5	lifespan	lifespan	VERB
aji-171	434	6	through	through	ADP
aji-171	434	7	ampk	ampk	PROPN
aji-171	434	8	α	α	PROPN
aji-171	434	9	parylation	parylation	NOUN
aji-171	434	10	and	and	CCONJ
aji-171	434	11	activation	activation	NOUN
aji-171	434	12	in	in	ADP
aji-171	434	13	drosophila	drosophila	NOUN
aji-171	434	14	.	.	PUNCT
aji-171	435	1	proceedings	proceeding	NOUN
aji-171	435	2	of	of	ADP
aji-171	435	3	the	the	DET
aji-171	435	4	national	national	PROPN
aji-171	435	5	academy	academy	PROPN
aji-171	435	6	of	of	ADP
aji-171	435	7	sciences	sciences	PROPN
aji-171	435	8	u.s.a	u.s.a	PROPN
aji-171	435	9	,	,	PUNCT
aji-171	435	10	120	120	NUM
aji-171	435	11	,	,	PUNCT
aji-171	435	12	2213857120	2213857120	NUM
aji-171	435	13	.	.	PUNCT
aji-171	436	1	ives	ive	NOUN
aji-171	436	2	,	,	PUNCT
aji-171	436	3	s.	s.	PROPN
aji-171	436	4	j.	j.	PROPN
aji-171	436	5	,	,	PUNCT
aji-171	436	6	zaleski	zaleski	PROPN
aji-171	436	7	,	,	PUNCT
aji-171	436	8	k.	k.	PROPN
aji-171	436	9	s.	s.	PROPN
aji-171	436	10	,	,	PUNCT
aji-171	436	11	slocum	slocum	PROPN
aji-171	436	12	,	,	PUNCT
aji-171	436	13	c.	c.	PROPN
aji-171	436	14	,	,	PUNCT
aji-171	436	15	escudero	escudero	PROPN
aji-171	436	16	,	,	PUNCT
aji-171	436	17	d.	d.	PROPN
aji-171	436	18	,	,	PUNCT
aji-171	436	19	sheridan	sheridan	PROPN
aji-171	436	20	,	,	PUNCT
aji-171	436	21	c.	c.	PROPN
aji-171	436	22	,	,	PUNCT
aji-171	436	23	legesse	legesse	NOUN
aji-171	436	24	,	,	PUNCT
aji-171	436	25	s.	s.	PROPN
aji-171	436	26	,	,	PUNCT
aji-171	436	27	vidal	vidal	NOUN
aji-171	436	28	,	,	PUNCT
aji-171	436	29	k.	k.	PROPN
aji-171	436	30	,	,	PUNCT
aji-171	436	31	lagalwar	lagalwar	PROPN
aji-171	436	32	,	,	PUNCT
aji-171	436	33	s.	s.	PROPN
aji-171	436	34	,	,	PUNCT
aji-171	436	35	&	&	CCONJ
aji-171	436	36	reynolds	reynolds	PROPN
aji-171	436	37	,	,	PUNCT
aji-171	436	38	t.	t.	PROPN
aji-171	436	39	h.	h.	PROPN
aji-171	436	40	(	(	PUNCT
aji-171	436	41	2020	2020	NUM
aji-171	436	42	)	)	PUNCT
aji-171	436	43	.	.	PUNCT
aji-171	437	1	the	the	DET
aji-171	437	2	effect	effect	NOUN
aji-171	437	3	of	of	ADP
aji-171	437	4	succinic	succinic	ADJ
aji-171	437	5	acid	acid	NOUN
aji-171	437	6	on	on	ADP
aji-171	437	7	the	the	DET
aji-171	437	8	metabolic	metabolic	NOUN
aji-171	437	9	profile	profile	NOUN
aji-171	437	10	in	in	ADP
aji-171	437	11	high	high	ADJ
aji-171	437	12	-	-	PUNCT
aji-171	437	13	fat	fat	NOUN
aji-171	437	14	diet	diet	NOUN
aji-171	437	15	-	-	PUNCT
aji-171	437	16	induced	induce	VERB
aji-171	437	17	obesity	obesity	NOUN
aji-171	437	18	and	and	CCONJ
aji-171	437	19	insulin	insulin	NOUN
aji-171	437	20	resistance	resistance	NOUN
aji-171	437	21	.	.	PUNCT
aji-171	438	1	physiological	physiological	ADJ
aji-171	438	2	reports	report	NOUN
aji-171	438	3	,	,	PUNCT
aji-171	438	4	8	8	NUM
aji-171	438	5	,	,	PUNCT
aji-171	438	6	21–32	21–32	NUM
aji-171	438	7	.	.	PUNCT
aji-171	439	1	jayamohananan	jayamohananan	PROPN
aji-171	439	2	,	,	PUNCT
aji-171	439	3	h.	h.	PROPN
aji-171	439	4	,	,	PUNCT
aji-171	439	5	kumar	kumar	PROPN
aji-171	439	6	,	,	PUNCT
aji-171	439	7	m.	m.	PROPN
aji-171	439	8	k.	k.	PROPN
aji-171	439	9	m.	m.	PROPN
aji-171	439	10	,	,	PUNCT
aji-171	439	11	&	&	CCONJ
aji-171	439	12	aneesh	aneesh	NOUN
aji-171	439	13	,	,	PUNCT
aji-171	439	14	t.	t.	PROPN
aji-171	439	15	(	(	PUNCT
aji-171	439	16	2019	2019	NUM
aji-171	439	17	)	)	PUNCT
aji-171	439	18	.	.	PUNCT
aji-171	440	1	5	5	NUM
aji-171	440	2	-	-	PUNCT
aji-171	440	3	hiaa	hiaa	NOUN
aji-171	440	4	as	as	ADP
aji-171	440	5	a	a	DET
aji-171	440	6	potential	potential	ADJ
aji-171	440	7	biological	biological	ADJ
aji-171	440	8	marker	marker	NOUN
aji-171	440	9	for	for	ADP
aji-171	440	10	neurological	neurological	ADJ
aji-171	440	11	and	and	CCONJ
aji-171	440	12	psychiatric	psychiatric	ADJ
aji-171	440	13	disorders	disorder	NOUN
aji-171	440	14	.	.	PUNCT
aji-171	441	1	advanced	advanced	ADJ
aji-171	441	2	pharmaceutical	pharmaceutical	ADJ
aji-171	441	3	bulletin	bulletin	NOUN
aji-171	441	4	,	,	PUNCT
aji-171	441	5	9	9	NUM
aji-171	441	6	,	,	PUNCT
aji-171	441	7	374	374	NUM
aji-171	441	8	.	.	PUNCT
aji-171	442	1	kes	kes	PROPN
aji-171	442	2	,	,	PUNCT
aji-171	442	3	m.	m.	NOUN
aji-171	442	4	m.	m.	NOUN
aji-171	442	5	,	,	PUNCT
aji-171	442	6	van	van	PROPN
aji-171	442	7	den	den	PROPN
aji-171	442	8	bossche	bossche	PROPN
aji-171	442	9	,	,	PUNCT
aji-171	442	10	j.	j.	PROPN
aji-171	442	11	,	,	PUNCT
aji-171	442	12	griffioen	griffioen	PROPN
aji-171	442	13	,	,	PUNCT
aji-171	442	14	a.	a.	PROPN
aji-171	442	15	w.	w.	PROPN
aji-171	442	16	,	,	PUNCT
aji-171	442	17	&	&	CCONJ
aji-171	442	18	huijbers	huijbers	PROPN
aji-171	442	19	,	,	PUNCT
aji-171	442	20	e.	e.	PROPN
aji-171	442	21	j.	j.	PROPN
aji-171	442	22	(	(	PUNCT
aji-171	442	23	2020	2020	NUM
aji-171	442	24	)	)	PUNCT
aji-171	442	25	.	.	PUNCT
aji-171	443	1	oncometabolites	oncometabolite	NOUN
aji-171	443	2	lactate	lactate	PROPN
aji-171	443	3	and	and	CCONJ
aji-171	443	4	succinate	succinate	NOUN
aji-171	443	5	drive	drive	NOUN
aji-171	443	6	pro	pro	ADJ
aji-171	443	7	-	-	ADJ
aji-171	443	8	angiogenic	angiogenic	ADJ
aji-171	443	9	macrophage	macrophage	ADJ
aji-171	443	10	response	response	NOUN
aji-171	443	11	in	in	ADP
aji-171	443	12	tumors	tumor	NOUN
aji-171	443	13	.	.	PUNCT
aji-171	444	1	biochemistry	biochemistry	NOUN
aji-171	444	2	.	.	PUNCT
aji-171	445	1	biophysical	biophysical	ADJ
aji-171	445	2	acta	acta	PROPN
aji-171	445	3	(	(	PUNCT
aji-171	445	4	bba	bba	NOUN
aji-171	445	5	)	)	PUNCT
aji-171	445	6	review	review	NOUN
aji-171	445	7	on	on	ADP
aji-171	445	8	cancer	cancer	NOUN
aji-171	445	9	,	,	PUNCT
aji-171	445	10	1874	1874	NUM
aji-171	445	11	,	,	PUNCT
aji-171	445	12	188427	188427	NUM
aji-171	445	13	.	.	PUNCT
aji-171	446	1	keski	keski	PROPN
aji-171	446	2	-	-	PUNCT
aji-171	446	3	rahkonen	rahkonen	NOUN
aji-171	446	4	,	,	PUNCT
aji-171	446	5	p.	p.	PROPN
aji-171	446	6	,	,	PUNCT
aji-171	446	7	robinson	robinson	PROPN
aji-171	446	8	,	,	PUNCT
aji-171	446	9	o.	o.	PROPN
aji-171	446	10	,	,	PUNCT
aji-171	446	11	alfano	alfano	PROPN
aji-171	446	12	,	,	PUNCT
aji-171	446	13	r.	r.	PROPN
aji-171	446	14	,	,	PUNCT
aji-171	446	15	plusquin	plusquin	NOUN
aji-171	446	16	,	,	PUNCT
aji-171	446	17	m.	m.	NOUN
aji-171	446	18	,	,	PUNCT
aji-171	446	19	&	&	CCONJ
aji-171	446	20	scalbert	scalbert	PROPN
aji-171	446	21	,	,	PUNCT
aji-171	446	22	a.	a.	NOUN
aji-171	446	23	(	(	PUNCT
aji-171	446	24	2021	2021	NUM
aji-171	446	25	)	)	PUNCT
aji-171	446	26	.	.	PUNCT
aji-171	447	1	commentary	commentary	NOUN
aji-171	447	2	:	:	PUNCT
aji-171	447	3	data	datum	NOUN
aji-171	447	4	processing	processing	NOUN
aji-171	447	5	thresholds	threshold	NOUN
aji-171	447	6	for	for	ADP
aji-171	447	7	abundance	abundance	NOUN
aji-171	447	8	and	and	CCONJ
aji-171	447	9	sparsity	sparsity	NOUN
aji-171	447	10	and	and	CCONJ
aji-171	447	11	missed	miss	VERB
aji-171	447	12	biological	biological	ADJ
aji-171	447	13	insights	insight	NOUN
aji-171	447	14	in	in	ADP
aji-171	447	15	an	an	DET
aji-171	447	16	untargeted	untargeted	ADJ
aji-171	447	17	chemical	chemical	NOUN
aji-171	447	18	analysis	analysis	NOUN
aji-171	447	19	of	of	ADP
aji-171	447	20	blood	blood	NOUN
aji-171	447	21	specimens	specimen	NOUN
aji-171	447	22	for	for	ADP
aji-171	447	23	exposomics	exposomic	NOUN
aji-171	447	24	.	.	PUNCT
aji-171	448	1	frontiers	frontier	NOUN
aji-171	448	2	in	in	ADP
aji-171	448	3	public	public	ADJ
aji-171	448	4	health	health	NOUN
aji-171	448	5	,	,	PUNCT
aji-171	448	6	9	9	NUM
aji-171	448	7	,	,	PUNCT
aji-171	448	8	755837	755837	NUM
aji-171	448	9	.	.	PUNCT
aji-171	449	1	https://doi.org/10.3389/fpubh.2021.755837	https://doi.org/10.3389/fpubh.2021.755837	PROPN
aji-171	449	2	kori	kori	PROPN
aji-171	449	3	,	,	PUNCT
aji-171	449	4	m.	m.	NOUN
aji-171	449	5	,	,	PUNCT
aji-171	449	6	aydın	aydın	PROPN
aji-171	449	7	,	,	PUNCT
aji-171	449	8	b.	b.	PROPN
aji-171	449	9	,	,	PUNCT
aji-171	449	10	unal	unal	ADJ
aji-171	449	11	,	,	PUNCT
aji-171	449	12	s.	s.	PROPN
aji-171	449	13	,	,	PUNCT
aji-171	449	14	arga	arga	PROPN
aji-171	449	15	,	,	PUNCT
aji-171	449	16	k.	k.	PROPN
aji-171	449	17	y.	y.	PROPN
aji-171	449	18	,	,	PUNCT
aji-171	449	19	&	&	CCONJ
aji-171	449	20	kazan	kazan	PROPN
aji-171	449	21	,	,	PUNCT
aji-171	449	22	d.	d.	PROPN
aji-171	449	23	(	(	PUNCT
aji-171	449	24	2016	2016	NUM
aji-171	449	25	)	)	PUNCT
aji-171	449	26	.	.	PUNCT
aji-171	450	1	metabolic	metabolic	NOUN
aji-171	450	2	biomarkers	biomarker	NOUN
aji-171	450	3	and	and	CCONJ
aji-171	450	4	neurodegeneration	neurodegeneration	NOUN
aji-171	450	5	:	:	PUNCT
aji-171	450	6	a	a	DET
aji-171	450	7	pathway	pathway	NOUN
aji-171	450	8	enrichment	enrichment	NOUN
aji-171	450	9	analysis	analysis	NOUN
aji-171	450	10	of	of	ADP
aji-171	450	11	alzheimer	alzheimer	PROPN
aji-171	450	12	’s	’s	PART
aji-171	450	13	disease	disease	NOUN
aji-171	450	14	,	,	PUNCT
aji-171	450	15	parkinson	parkinson	NOUN
aji-171	450	16	’s	’s	PART
aji-171	450	17	disease	disease	NOUN
aji-171	450	18	,	,	PUNCT
aji-171	450	19	and	and	CCONJ
aji-171	450	20	amyotrophic	amyotrophic	ADJ
aji-171	450	21	lateral	lateral	ADJ
aji-171	450	22	sclerosis	sclerosis	NOUN
aji-171	450	23	.	.	PUNCT
aji-171	451	1	omics	omic	NOUN
aji-171	451	2	:	:	PUNCT
aji-171	451	3	a	a	DET
aji-171	451	4	journal	journal	NOUN
aji-171	451	5	of	of	ADP
aji-171	451	6	integrative	integrative	ADJ
aji-171	451	7	biology	biology	NOUN
aji-171	451	8	,	,	PUNCT
aji-171	451	9	20	20	NUM
aji-171	451	10	,	,	PUNCT
aji-171	451	11	645	645	NUM
aji-171	451	12	–	–	PUNCT
aji-171	451	13	661	661	NUM
aji-171	451	14	.	.	PUNCT
aji-171	452	1	kremer	kremer	PROPN
aji-171	452	2	,	,	PUNCT
aji-171	452	3	t.	t.	PROPN
aji-171	452	4	,	,	PUNCT
aji-171	452	5	taylor	taylor	PROPN
aji-171	452	6	,	,	PUNCT
aji-171	452	7	k.	k.	PROPN
aji-171	452	8	i.	i.	PROPN
aji-171	452	9	,	,	PUNCT
aji-171	452	10	siebourg	siebourg	NOUN
aji-171	452	11	-	-	PUNCT
aji-171	452	12	polster	polster	NOUN
aji-171	452	13	,	,	PUNCT
aji-171	452	14	j.	j.	PROPN
aji-171	452	15	,	,	PUNCT
aji-171	452	16	gerken	gerken	VERB
aji-171	452	17	,	,	PUNCT
aji-171	452	18	t.	t.	NOUN
aji-171	452	19	,	,	PUNCT
aji-171	452	20	staempfli	staempfli	NOUN
aji-171	452	21	,	,	PUNCT
aji-171	452	22	a.	a.	NOUN
aji-171	452	23	,	,	PUNCT
aji-171	452	24	czech	czech	PROPN
aji-171	452	25	,	,	PUNCT
aji-171	452	26	c.	c.	PROPN
aji-171	452	27	,	,	PUNCT
aji-171	452	28	dukart	dukart	NOUN
aji-171	452	29	,	,	PUNCT
aji-171	452	30	j.	j.	PROPN
aji-171	452	31	,	,	PUNCT
aji-171	452	32	galasko	galasko	PROPN
aji-171	452	33	,	,	PUNCT
aji-171	452	34	d.	d.	PROPN
aji-171	452	35	,	,	PUNCT
aji-171	452	36	foroud	foroud	ADJ
aji-171	452	37	,	,	PUNCT
aji-171	452	38	t.	t.	NOUN
aji-171	452	39	,	,	PUNCT
aji-171	452	40	&	&	CCONJ
aji-171	452	41	chahine	chahine	PROPN
aji-171	452	42	,	,	PUNCT
aji-171	452	43	l.	l.	PROPN
aji-171	452	44	m.	m.	PROPN
aji-171	452	45	(	(	PUNCT
aji-171	452	46	2021	2021	NUM
aji-171	452	47	)	)	PUNCT
aji-171	452	48	.	.	PUNCT
aji-171	453	1	longitudinal	longitudinal	ADJ
aji-171	453	2	analysis	analysis	NOUN
aji-171	453	3	of	of	ADP
aji-171	453	4	multiple	multiple	ADJ
aji-171	453	5	neurotransmitter	neurotransmitter	NOUN
aji-171	453	6	metabolites	metabolite	NOUN
aji-171	453	7	in	in	ADP
aji-171	453	8	cerebrospinal	cerebrospinal	ADJ
aji-171	453	9	fluid	fluid	NOUN
aji-171	453	10	in	in	ADP
aji-171	453	11	early	early	ADJ
aji-171	453	12	parkinson	parkinson	NOUN
aji-171	453	13	’s	’s	PART
aji-171	453	14	disease	disease	NOUN
aji-171	453	15	.	.	PUNCT
aji-171	454	1	movement	movement	NOUN
aji-171	454	2	disorders	disorder	NOUN
aji-171	454	3	,	,	PUNCT
aji-171	454	4	36	36	NUM
aji-171	454	5	,	,	PUNCT
aji-171	454	6	1972–1978	1972–1978	NUM
aji-171	454	7	.	.	PUNCT
aji-171	454	8	lanzetti	lanzetti	PROPN
aji-171	454	9	,	,	PUNCT
aji-171	454	10	l.	l.	PROPN
aji-171	454	11	(	(	PUNCT
aji-171	454	12	2024	2024	NUM
aji-171	454	13	)	)	PUNCT
aji-171	454	14	.	.	PUNCT
aji-171	455	1	oncometabolites	oncometabolite	NOUN
aji-171	455	2	at	at	ADP
aji-171	455	3	the	the	DET
aji-171	455	4	crossroads	crossroad	NOUN
aji-171	455	5	of	of	ADP
aji-171	455	6	genetic	genetic	ADJ
aji-171	455	7	,	,	PUNCT
aji-171	455	8	epigenetic	epigenetic	ADJ
aji-171	455	9	and	and	CCONJ
aji-171	455	10	ecological	ecological	ADJ
aji-171	455	11	alterations	alteration	NOUN
aji-171	455	12	in	in	ADP
aji-171	455	13	cancer	cancer	NOUN
aji-171	455	14	.	.	PUNCT
aji-171	456	1	cell	cell	NOUN
aji-171	456	2	death	death	NOUN
aji-171	456	3	differentiation	differentiation	NOUN
aji-171	456	4	,	,	PUNCT
aji-171	456	5	1–13	1–13	NOUN
aji-171	456	6	.	.	PUNCT
aji-171	457	1	lanznaster	lanznaster	PROPN
aji-171	457	2	,	,	PUNCT
aji-171	457	3	d.	d.	PROPN
aji-171	457	4	,	,	PUNCT
aji-171	457	5	de	de	X
aji-171	457	6	assis	assis	PROPN
aji-171	457	7	,	,	PUNCT
aji-171	457	8	d.	d.	PROPN
aji-171	457	9	r.	r.	PROPN
aji-171	457	10	,	,	PUNCT
aji-171	457	11	corcia	corcia	PROPN
aji-171	457	12	,	,	PUNCT
aji-171	457	13	p.	p.	NOUN
aji-171	457	14	,	,	PUNCT
aji-171	457	15	pradat	pradat	PROPN
aji-171	457	16	,	,	PUNCT
aji-171	457	17	p.	p.	PROPN
aji-171	457	18	f.	f.	PROPN
aji-171	457	19	,	,	PUNCT
aji-171	457	20	&	&	CCONJ
aji-171	457	21	blasco	blasco	PROPN
aji-171	457	22	,	,	PUNCT
aji-171	457	23	h.	h.	PROPN
aji-171	457	24	(	(	PUNCT
aji-171	457	25	2018	2018	NUM
aji-171	457	26	)	)	PUNCT
aji-171	457	27	.	.	PUNCT
aji-171	458	1	metabolomics	metabolomic	NOUN
aji-171	458	2	biomarkers	biomarker	NOUN
aji-171	458	3	:	:	PUNCT
aji-171	458	4	a	a	DET
aji-171	458	5	strategy	strategy	NOUN
aji-171	458	6	toward	toward	ADP
aji-171	458	7	therapeutics	therapeutic	NOUN
aji-171	458	8	improvement	improvement	NOUN
aji-171	458	9	in	in	ADP
aji-171	458	10	als	al	NOUN
aji-171	458	11	.	.	PUNCT
aji-171	459	1	frontiers	frontier	NOUN
aji-171	459	2	in	in	ADP
aji-171	459	3	neurology	neurology	NOUN
aji-171	459	4	,	,	PUNCT
aji-171	459	5	9	9	NUM
aji-171	459	6	,	,	PUNCT
aji-171	459	7	1126	1126	NUM
aji-171	459	8	.	.	PUNCT
aji-171	460	1	le	le	PROPN
aji-171	460	2	gouellec	gouellec	PROPN
aji-171	460	3	,	,	PUNCT
aji-171	460	4	a.	a.	NOUN
aji-171	460	5	,	,	PUNCT
aji-171	460	6	plazy	plazy	NOUN
aji-171	460	7	,	,	PUNCT
aji-171	460	8	c.	c.	PROPN
aji-171	460	9	,	,	PUNCT
aji-171	460	10	&	&	CCONJ
aji-171	460	11	toussaint	toussaint	PROPN
aji-171	460	12	,	,	PUNCT
aji-171	460	13	b.	b.	PROPN
aji-171	460	14	(	(	PUNCT
aji-171	460	15	2023	2023	NUM
aji-171	460	16	)	)	PUNCT
aji-171	460	17	.	.	PUNCT
aji-171	461	1	what	what	PRON
aji-171	461	2	clinical	clinical	ADJ
aji-171	461	3	metabolomics	metabolomic	NOUN
aji-171	461	4	will	will	AUX
aji-171	461	5	bring	bring	VERB
aji-171	461	6	to	to	ADP
aji-171	461	7	the	the	DET
aji-171	461	8	medicine	medicine	NOUN
aji-171	461	9	of	of	ADP
aji-171	461	10	tomorrow	tomorrow	NOUN
aji-171	461	11	.	.	PUNCT
aji-171	462	1	frontiers	frontier	NOUN
aji-171	462	2	in	in	ADP
aji-171	462	3	analytical	analytical	ADJ
aji-171	462	4	sciences	science	NOUN
aji-171	462	5	,	,	PUNCT
aji-171	462	6	3	3	NUM
aji-171	462	7	,	,	PUNCT
aji-171	462	8	1142606	1142606	NUM
aji-171	462	9	.	.	PUNCT
aji-171	463	1	lempesis	lempesis	NOUN
aji-171	463	2	,	,	PUNCT
aji-171	463	3	i.	i.	PROPN
aji-171	463	4	g.	g.	PROPN
aji-171	463	5	,	,	PUNCT
aji-171	463	6	tsilingiris	tsilingiris	PROPN
aji-171	463	7	,	,	PUNCT
aji-171	463	8	d.	d.	PROPN
aji-171	463	9	,	,	PUNCT
aji-171	463	10	liu	liu	PROPN
aji-171	463	11	,	,	PUNCT
aji-171	463	12	j.	j.	PROPN
aji-171	463	13	,	,	PUNCT
aji-171	463	14	&	&	CCONJ
aji-171	463	15	dalamaga	dalamaga	NOUN
aji-171	463	16	,	,	PUNCT
aji-171	463	17	m.	m.	NOUN
aji-171	463	18	(	(	PUNCT
aji-171	463	19	2022	2022	NUM
aji-171	463	20	)	)	PUNCT
aji-171	463	21	.	.	PUNCT
aji-171	464	1	of	of	ADP
aji-171	464	2	mice	mouse	NOUN
aji-171	464	3	and	and	CCONJ
aji-171	464	4	men	man	NOUN
aji-171	464	5	:	:	PUNCT
aji-171	464	6	considerations	consideration	NOUN
aji-171	464	7	on	on	ADP
aji-171	464	8	adipose	adipose	PRON
aji-171	464	9	tissue	tissue	NOUN
aji-171	464	10	physiology	physiology	NOUN
aji-171	464	11	in	in	ADP
aji-171	464	12	animal	animal	NOUN
aji-171	464	13	models	model	NOUN
aji-171	464	14	of	of	ADP
aji-171	464	15	obesity	obesity	NOUN
aji-171	464	16	and	and	CCONJ
aji-171	464	17	human	human	ADJ
aji-171	464	18	studies	study	NOUN
aji-171	464	19	.	.	PUNCT
aji-171	465	1	metabolism	metabolism	NOUN
aji-171	465	2	open	open	ADJ
aji-171	465	3	,	,	PUNCT
aji-171	465	4	15	15	NUM
aji-171	465	5	,	,	PUNCT
aji-171	465	6	100208	100208	NUM
aji-171	465	7	.	.	PUNCT
aji-171	466	1	li	li	PROPN
aji-171	466	2	,	,	PUNCT
aji-171	466	3	x.	x.	PROPN
aji-171	466	4	,	,	PUNCT
aji-171	466	5	zhang	zhang	PROPN
aji-171	466	6	,	,	PUNCT
aji-171	466	7	a.	a.	PROPN
aji-171	466	8	,	,	PUNCT
aji-171	466	9	sun	sun	PROPN
aji-171	466	10	,	,	PUNCT
aji-171	466	11	h.	h.	PROPN
aji-171	466	12	,	,	PUNCT
aji-171	466	13	liu	liu	PROPN
aji-171	466	14	,	,	PUNCT
aji-171	466	15	z.	z.	PROPN
aji-171	466	16	,	,	PUNCT
aji-171	466	17	zhang	zhang	PROPN
aji-171	466	18	,	,	PUNCT
aji-171	466	19	t.	t.	PROPN
aji-171	466	20	,	,	PUNCT
aji-171	466	21	&	&	CCONJ
aji-171	466	22	qiu	qiu	PROPN
aji-171	466	23	,	,	PUNCT
aji-171	466	24	s.	s.	PROPN
aji-171	466	25	(	(	PUNCT
aji-171	466	26	2017	2017	NUM
aji-171	466	27	)	)	PUNCT
aji-171	466	28	.	.	PUNCT
aji-171	467	1	metabolic	metabolic	NOUN
aji-171	467	2	characterization	characterization	NOUN
aji-171	467	3	and	and	CCONJ
aji-171	467	4	pathway	pathway	NOUN
aji-171	467	5	analysis	analysis	NOUN
aji-171	467	6	of	of	ADP
aji-171	467	7	berberine	berberine	NOUN
aji-171	467	8	protects	protect	VERB
aji-171	467	9	against	against	ADP
aji-171	467	10	prostate	prostate	NOUN
aji-171	467	11	cancer	cancer	NOUN
aji-171	467	12	.	.	PUNCT
aji-171	468	1	oncotarget	oncotarget	NOUN
aji-171	468	2	,	,	PUNCT
aji-171	468	3	8(39	8(39	NUM
aji-171	468	4	)	)	PUNCT
aji-171	468	5	,	,	PUNCT
aji-171	468	6	65022	65022	NUM
aji-171	468	7	.	.	PUNCT
aji-171	469	1	liberti	liberti	PROPN
aji-171	469	2	,	,	PUNCT
aji-171	469	3	m.	m.	NOUN
aji-171	469	4	v.	v.	PROPN
aji-171	469	5	,	,	PUNCT
aji-171	469	6	&	&	CCONJ
aji-171	469	7	locasale	locasale	PROPN
aji-171	469	8	,	,	PUNCT
aji-171	469	9	j.	j.	PROPN
aji-171	469	10	w.	w.	PROPN
aji-171	469	11	(	(	PUNCT
aji-171	469	12	2016	2016	NUM
aji-171	469	13	)	)	PUNCT
aji-171	469	14	.	.	PUNCT
aji-171	470	1	the	the	DET
aji-171	470	2	warburg	warburg	NOUN
aji-171	470	3	effect	effect	NOUN
aji-171	470	4	:	:	PUNCT
aji-171	470	5	how	how	SCONJ
aji-171	470	6	does	do	AUX
aji-171	470	7	it	it	PRON
aji-171	470	8	benefit	benefit	VERB
aji-171	470	9	cancer	cancer	NOUN
aji-171	470	10	cells	cell	NOUN
aji-171	470	11	?	?	PUNCT
aji-171	471	1	trends	trend	NOUN
aji-171	471	2	in	in	ADP
aji-171	471	3	biochemical	biochemical	ADJ
aji-171	471	4	sciences	science	NOUN
aji-171	471	5	,	,	PUNCT
aji-171	471	6	41	41	NUM
aji-171	471	7	,	,	PUNCT
aji-171	471	8	211–218	211–218	NUM
aji-171	471	9	.	.	PUNCT
aji-171	472	1	lieu	lieu	PROPN
aji-171	472	2	,	,	PUNCT
aji-171	472	3	e.	e.	PROPN
aji-171	472	4	l.	l.	PROPN
aji-171	472	5	,	,	PUNCT
aji-171	472	6	nguyen	nguyen	PROPN
aji-171	472	7	,	,	PUNCT
aji-171	472	8	t.	t.	PROPN
aji-171	472	9	,	,	PUNCT
aji-171	472	10	rhyne	rhyne	PROPN
aji-171	472	11	,	,	PUNCT
aji-171	472	12	s.	s.	PROPN
aji-171	472	13	,	,	PUNCT
aji-171	472	14	&	&	CCONJ
aji-171	472	15	kim	kim	PROPN
aji-171	472	16	,	,	PUNCT
aji-171	472	17	j.	j.	PROPN
aji-171	472	18	(	(	PUNCT
aji-171	472	19	2020	2020	NUM
aji-171	472	20	)	)	PUNCT
aji-171	472	21	.	.	PUNCT
aji-171	473	1	amino	amino	ADJ
aji-171	473	2	acids	acid	NOUN
aji-171	473	3	in	in	ADP
aji-171	473	4	cancer	cancer	NOUN
aji-171	473	5	.	.	PUNCT
aji-171	474	1	experimental	experimental	ADJ
aji-171	474	2	and	and	CCONJ
aji-171	474	3	molecular	molecular	ADJ
aji-171	474	4	medicine	medicine	NOUN
aji-171	474	5	,	,	PUNCT
aji-171	474	6	52	52	NUM
aji-171	474	7	,	,	PUNCT
aji-171	474	8	15–30	15–30	NUM
aji-171	474	9	.	.	PUNCT
aji-171	475	1	liu	liu	PROPN
aji-171	475	2	,	,	PUNCT
aji-171	475	3	y.	y.	PROPN
aji-171	475	4	,	,	PUNCT
aji-171	475	5	&	&	CCONJ
aji-171	475	6	yang	yang	PROPN
aji-171	475	7	,	,	PUNCT
aji-171	475	8	c.	c.	PROPN
aji-171	475	9	(	(	PUNCT
aji-171	475	10	2021	2021	NUM
aji-171	475	11	)	)	PUNCT
aji-171	475	12	.	.	PUNCT
aji-171	476	1	oncometabolites	oncometabolite	NOUN
aji-171	476	2	in	in	ADP
aji-171	476	3	cancer	cancer	NOUN
aji-171	476	4	:	:	PUNCT
aji-171	476	5	current	current	ADJ
aji-171	476	6	understanding	understanding	NOUN
aji-171	476	7	and	and	CCONJ
aji-171	476	8	mamman	mamman	NOUN
aji-171	476	9	et	et	PROPN
aji-171	476	10	al	al	PROPN
aji-171	476	11	.	.	PROPN
aji-171	476	12	;	;	PUNCT
aji-171	476	13	asian	asian	PROPN
aji-171	476	14	j.	j.	PROPN
aji-171	476	15	immunol	immunol	PROPN
aji-171	476	16	.	.	PROPN
aji-171	476	17	,	,	PUNCT
aji-171	476	18	vol	vol	NOUN
aji-171	476	19	.	.	PROPN
aji-171	476	20	8	8	NUM
aji-171	476	21	,	,	PUNCT
aji-171	476	22	no	no	INTJ
aji-171	476	23	.	.	NOUN
aji-171	476	24	1	1	NUM
aji-171	476	25	,	,	PUNCT
aji-171	476	26	pp	pp	ADJ
aji-171	476	27	.	.	PUNCT
aji-171	477	1	190	190	NUM
aji-171	477	2	-	-	SYM
aji-171	477	3	206	206	NUM
aji-171	477	4	,	,	PUNCT
aji-171	477	5	2025	2025	NUM
aji-171	477	6	;	;	PUNCT
aji-171	477	7	article	article	NOUN
aji-171	477	8	no.aji.140476	no.aji.140476	ADV
aji-171	477	9	203	203	NUM
aji-171	477	10	challenges	challenge	NOUN
aji-171	477	11	.	.	PUNCT
aji-171	478	1	cancer	cancer	NOUN
aji-171	478	2	research	research	NOUN
aji-171	478	3	,	,	PUNCT
aji-171	478	4	81	81	NUM
aji-171	478	5	,	,	PUNCT
aji-171	478	6	2820	2820	NUM
aji-171	478	7	–	–	PUNCT
aji-171	478	8	2823	2823	NUM
aji-171	478	9	.	.	PUNCT
aji-171	479	1	luo	luo	PROPN
aji-171	479	2	,	,	PUNCT
aji-171	479	3	h.	h.	PROPN
aji-171	479	4	h.	h.	PROPN
aji-171	479	5	,	,	PUNCT
aji-171	479	6	li	li	PROPN
aji-171	479	7	,	,	PUNCT
aji-171	479	8	j.	j.	PROPN
aji-171	479	9	,	,	PUNCT
aji-171	479	10	feng	feng	PROPN
aji-171	479	11	,	,	PUNCT
aji-171	479	12	x.	x.	PROPN
aji-171	479	13	f.	f.	PROPN
aji-171	479	14	,	,	PUNCT
aji-171	479	15	sun	sun	PROPN
aji-171	479	16	,	,	PUNCT
aji-171	479	17	x.	x.	NOUN
aji-171	479	18	y.	y.	PROPN
aji-171	479	19	,	,	PUNCT
aji-171	479	20	li	li	PROPN
aji-171	479	21	,	,	PUNCT
aji-171	479	22	j.	j.	PROPN
aji-171	479	23	,	,	PUNCT
aji-171	479	24	yang	yang	PROPN
aji-171	479	25	,	,	PUNCT
aji-171	479	26	x.	x.	PROPN
aji-171	479	27	,	,	PUNCT
aji-171	479	28	&	&	CCONJ
aji-171	479	29	fang	fang	PROPN
aji-171	479	30	,	,	PUNCT
aji-171	479	31	z.	z.	PROPN
aji-171	479	32	z.	z.	PROPN
aji-171	479	33	(	(	PUNCT
aji-171	479	34	2020	2020	NUM
aji-171	479	35	)	)	PUNCT
aji-171	479	36	.	.	PUNCT
aji-171	480	1	plasma	plasma	NOUN
aji-171	480	2	phenylalanine	phenylalanine	NOUN
aji-171	480	3	and	and	CCONJ
aji-171	480	4	tyrosine	tyrosine	NOUN
aji-171	480	5	and	and	CCONJ
aji-171	480	6	their	their	PRON
aji-171	480	7	interactions	interaction	NOUN
aji-171	480	8	with	with	ADP
aji-171	480	9	diabetic	diabetic	ADJ
aji-171	480	10	nephropathy	nephropathy	NOUN
aji-171	480	11	for	for	ADP
aji-171	480	12	risk	risk	NOUN
aji-171	480	13	of	of	ADP
aji-171	480	14	diabetic	diabetic	ADJ
aji-171	480	15	retinopathy	retinopathy	NOUN
aji-171	480	16	in	in	ADP
aji-171	480	17	type	type	NOUN
aji-171	480	18	2	2	NUM
aji-171	480	19	diabetes	diabetes	NOUN
aji-171	480	20	.	.	PUNCT
aji-171	481	1	bmj	bmj	PROPN
aji-171	481	2	open	open	ADJ
aji-171	481	3	diabetes	diabetes	NOUN
aji-171	481	4	research	research	NOUN
aji-171	481	5	and	and	CCONJ
aji-171	481	6	care	care	NOUN
aji-171	481	7	,	,	PUNCT
aji-171	481	8	8	8	NUM
aji-171	481	9	,	,	PUNCT
aji-171	481	10	877	877	NUM
aji-171	481	11	.	.	PUNCT
aji-171	482	1	lynch	lynch	PROPN
aji-171	482	2	,	,	PUNCT
aji-171	482	3	c.	c.	PROPN
aji-171	482	4	j.	j.	PROPN
aji-171	482	5	,	,	PUNCT
aji-171	482	6	&	&	CCONJ
aji-171	482	7	adams	adams	PROPN
aji-171	482	8	,	,	PUNCT
aji-171	482	9	s.	s.	PROPN
aji-171	482	10	h.	h.	PROPN
aji-171	482	11	(	(	PUNCT
aji-171	482	12	2014	2014	NUM
aji-171	482	13	)	)	PUNCT
aji-171	482	14	.	.	PUNCT
aji-171	483	1	branchedchain	branchedchain	NOUN
aji-171	483	2	amino	amino	NOUN
aji-171	483	3	acids	acid	NOUN
aji-171	483	4	in	in	ADP
aji-171	483	5	metabolic	metabolic	NOUN
aji-171	483	6	signalling	signal	VERB
aji-171	483	7	and	and	CCONJ
aji-171	483	8	insulin	insulin	NOUN
aji-171	483	9	resistance	resistance	NOUN
aji-171	483	10	.	.	PUNCT
aji-171	484	1	nature	nature	NOUN
aji-171	484	2	reviews	review	VERB
aji-171	484	3	endocrinology	endocrinology	NOUN
aji-171	484	4	,	,	PUNCT
aji-171	484	5	10	10	NUM
aji-171	484	6	,	,	PUNCT
aji-171	484	7	723–736	723–736	NUM
aji-171	484	8	.	.	PUNCT
aji-171	485	1	mallu	mallu	PROPN
aji-171	485	2	,	,	PUNCT
aji-171	485	3	m.	m.	PROPN
aji-171	485	4	r.	r.	PROPN
aji-171	485	5	,	,	PUNCT
aji-171	485	6	anjum	anjum	PROPN
aji-171	485	7	,	,	PUNCT
aji-171	485	8	s.	s.	PROPN
aji-171	485	9	m.	m.	PROPN
aji-171	485	10	,	,	PUNCT
aji-171	485	11	katravulapalli	katravulapalli	PROPN
aji-171	485	12	,	,	PUNCT
aji-171	485	13	s.	s.	PROPN
aji-171	485	14	s.	s.	PROPN
aji-171	485	15	s.	s.	PROPN
aji-171	485	16	,	,	PUNCT
aji-171	485	17	avuthu	avuthu	PROPN
aji-171	485	18	,	,	PUNCT
aji-171	485	19	s.	s.	PROPN
aji-171	485	20	s.	s.	PROPN
aji-171	485	21	p.	p.	PROPN
aji-171	485	22	,	,	PUNCT
aji-171	485	23	gujjula	gujjula	PROPN
aji-171	485	24	,	,	PUNCT
aji-171	485	25	k.	k.	PROPN
aji-171	485	26	r.	r.	PROPN
aji-171	485	27	,	,	PUNCT
aji-171	485	28	veeravilli	veeravilli	PROPN
aji-171	485	29	,	,	PUNCT
aji-171	485	30	s.	s.	PROPN
aji-171	485	31	,	,	PUNCT
aji-171	485	32	&	&	CCONJ
aji-171	485	33	manne	manne	PROPN
aji-171	485	34	,	,	PUNCT
aji-171	485	35	a.	a.	NOUN
aji-171	485	36	a.	a.	NOUN
aji-171	485	37	(	(	PUNCT
aji-171	485	38	2021	2021	NUM
aji-171	485	39	)	)	PUNCT
aji-171	485	40	.	.	PUNCT
aji-171	486	1	metabolomic	metabolomic	ADJ
aji-171	486	2	interactions	interaction	NOUN
aji-171	486	3	:	:	PUNCT
aji-171	486	4	an	an	DET
aji-171	486	5	insight	insight	NOUN
aji-171	486	6	into	into	ADP
aji-171	486	7	health	health	NOUN
aji-171	486	8	and	and	CCONJ
aji-171	486	9	disease	disease	NOUN
aji-171	486	10	.	.	PUNCT
aji-171	487	1	journal	journal	PROPN
aji-171	487	2	of	of	ADP
aji-171	487	3	pharmaceutical	pharmaceutical	PROPN
aji-171	487	4	research	research	PROPN
aji-171	487	5	international	international	PROPN
aji-171	487	6	,	,	PUNCT
aji-171	487	7	33(39a	33(39a	NUM
aji-171	487	8	)	)	PUNCT
aji-171	487	9	,	,	PUNCT
aji-171	487	10	61–67	61–67	NUM
aji-171	487	11	.	.	PUNCT
aji-171	488	1	https://doi.org/10.9734/jpri/2021/v33i39a32	https://doi.org/10.9734/jpri/2021/v33i39a32	PROPN
aji-171	488	2	142	142	NUM
aji-171	488	3	marko	marko	PROPN
aji-171	488	4	,	,	PUNCT
aji-171	488	5	d.	d.	PROPN
aji-171	488	6	m.	m.	PROPN
aji-171	488	7	,	,	PUNCT
aji-171	488	8	conn	conn	PROPN
aji-171	488	9	,	,	PUNCT
aji-171	488	10	m.	m.	NOUN
aji-171	488	11	o.	o.	PROPN
aji-171	488	12	,	,	PUNCT
aji-171	488	13	&	&	CCONJ
aji-171	488	14	schertzer	schertzer	PROPN
aji-171	488	15	,	,	PUNCT
aji-171	488	16	j.	j.	PROPN
aji-171	488	17	d.	d.	PROPN
aji-171	488	18	(	(	PUNCT
aji-171	488	19	2024	2024	NUM
aji-171	488	20	)	)	PUNCT
aji-171	488	21	.	.	PUNCT
aji-171	489	1	intermittent	intermittent	ADJ
aji-171	489	2	fasting	fasting	NOUN
aji-171	489	3	influences	influence	VERB
aji-171	489	4	immunity	immunity	NOUN
aji-171	489	5	and	and	CCONJ
aji-171	489	6	metabolism	metabolism	NOUN
aji-171	489	7	.	.	PUNCT
aji-171	490	1	trends	trend	NOUN
aji-171	490	2	in	in	ADP
aji-171	490	3	endocrinology	endocrinology	NOUN
aji-171	490	4	metabolism	metabolism	NOUN
aji-171	490	5	,	,	PUNCT
aji-171	490	6	35	35	NUM
aji-171	490	7	,	,	PUNCT
aji-171	490	8	821–833	821–833	NUM
aji-171	490	9	.	.	PUNCT
aji-171	491	1	marx	marx	PROPN
aji-171	491	2	,	,	PUNCT
aji-171	491	3	w.	w.	PROPN
aji-171	491	4	,	,	PUNCT
aji-171	491	5	mcguinness	mcguinness	PROPN
aji-171	491	6	,	,	PUNCT
aji-171	491	7	a.	a.	PROPN
aji-171	491	8	j.	j.	PROPN
aji-171	491	9	,	,	PUNCT
aji-171	491	10	rocks	rocks	PROPN
aji-171	491	11	,	,	PUNCT
aji-171	491	12	t.	t.	PROPN
aji-171	491	13	,	,	PUNCT
aji-171	491	14	ruusunen	ruusunen	PROPN
aji-171	491	15	,	,	PUNCT
aji-171	491	16	a.	a.	PROPN
aji-171	491	17	,	,	PUNCT
aji-171	491	18	cleminson	cleminson	NOUN
aji-171	491	19	,	,	PUNCT
aji-171	491	20	j.	j.	PROPN
aji-171	491	21	,	,	PUNCT
aji-171	491	22	walker	walker	PROPN
aji-171	491	23	,	,	PUNCT
aji-171	491	24	a.	a.	PROPN
aji-171	491	25	j.	j.	PROPN
aji-171	491	26	,	,	PUNCT
aji-171	491	27	gomes	gomes	PROPN
aji-171	491	28	-	-	PUNCT
aji-171	491	29	da	da	NOUN
aji-171	491	30	-	-	PUNCT
aji-171	491	31	costa	costa	NOUN
aji-171	491	32	,	,	PUNCT
aji-171	491	33	s.	s.	PROPN
aji-171	491	34	,	,	PUNCT
aji-171	491	35	lane	lane	NOUN
aji-171	491	36	,	,	PUNCT
aji-171	491	37	m.	m.	NOUN
aji-171	491	38	,	,	PUNCT
aji-171	491	39	sanches	sanche	NOUN
aji-171	491	40	,	,	PUNCT
aji-171	491	41	m.	m.	NOUN
aji-171	491	42	,	,	PUNCT
aji-171	491	43	&	&	CCONJ
aji-171	491	44	diaz	diaz	PROPN
aji-171	491	45	,	,	PUNCT
aji-171	491	46	a.	a.	NOUN
aji-171	491	47	p.	p.	NOUN
aji-171	491	48	(	(	PUNCT
aji-171	491	49	2021	2021	NUM
aji-171	491	50	)	)	PUNCT
aji-171	491	51	.	.	PUNCT
aji-171	492	1	the	the	DET
aji-171	492	2	kynurenine	kynurenine	NOUN
aji-171	492	3	pathway	pathway	NOUN
aji-171	492	4	in	in	ADP
aji-171	492	5	major	major	ADJ
aji-171	492	6	depressive	depressive	ADJ
aji-171	492	7	disorder	disorder	NOUN
aji-171	492	8	,	,	PUNCT
aji-171	492	9	bipolar	bipolar	ADJ
aji-171	492	10	disorder	disorder	NOUN
aji-171	492	11	,	,	PUNCT
aji-171	492	12	and	and	CCONJ
aji-171	492	13	schizophrenia	schizophrenia	NOUN
aji-171	492	14	:	:	PUNCT
aji-171	492	15	a	a	DET
aji-171	492	16	meta	meta	ADJ
aji-171	492	17	-	-	PUNCT
aji-171	492	18	analysis	analysis	NOUN
aji-171	492	19	of	of	ADP
aji-171	492	20	101	101	NUM
aji-171	492	21	studies	study	NOUN
aji-171	492	22	.	.	PUNCT
aji-171	493	1	molecular	molecular	ADJ
aji-171	493	2	psychiatry	psychiatry	NOUN
aji-171	493	3	,	,	PUNCT
aji-171	493	4	26	26	NUM
aji-171	493	5	,	,	PUNCT
aji-171	493	6	4158	4158	NUM
aji-171	493	7	–	–	PUNCT
aji-171	493	8	4178	4178	NUM
aji-171	493	9	.	.	PUNCT
aji-171	494	1	mateo	mateo	PROPN
aji-171	494	2	,	,	PUNCT
aji-171	494	3	j.	j.	PROPN
aji-171	494	4	,	,	PUNCT
aji-171	494	5	steuten	steuten	PROPN
aji-171	494	6	,	,	PUNCT
aji-171	494	7	l.	l.	PROPN
aji-171	494	8	,	,	PUNCT
aji-171	494	9	aftimos	aftimos	PROPN
aji-171	494	10	,	,	PUNCT
aji-171	494	11	p.	p.	PROPN
aji-171	494	12	,	,	PUNCT
aji-171	494	13	andré	andré	VERB
aji-171	494	14	,	,	PUNCT
aji-171	494	15	f.	f.	PROPN
aji-171	494	16	,	,	PUNCT
aji-171	494	17	davies	davy	NOUN
aji-171	494	18	,	,	PUNCT
aji-171	494	19	m.	m.	NOUN
aji-171	494	20	,	,	PUNCT
aji-171	494	21	garralda	garralda	PROPN
aji-171	494	22	,	,	PUNCT
aji-171	494	23	e.	e.	PROPN
aji-171	494	24	,	,	PUNCT
aji-171	494	25	geissler	geissler	NOUN
aji-171	494	26	,	,	PUNCT
aji-171	494	27	j.	j.	PROPN
aji-171	494	28	,	,	PUNCT
aji-171	494	29	husereau	husereau	PROPN
aji-171	494	30	,	,	PUNCT
aji-171	494	31	d.	d.	PROPN
aji-171	494	32	,	,	PUNCT
aji-171	494	33	martinez	martinez	PROPN
aji-171	494	34	-	-	PUNCT
aji-171	494	35	lopez	lopez	PROPN
aji-171	494	36	,	,	PUNCT
aji-171	494	37	i.	i.	PROPN
aji-171	494	38	,	,	PUNCT
aji-171	494	39	&	&	CCONJ
aji-171	494	40	normanno	normanno	VERB
aji-171	494	41	,	,	PUNCT
aji-171	494	42	n.	n.	NOUN
aji-171	494	43	(	(	PUNCT
aji-171	494	44	2022	2022	NUM
aji-171	494	45	)	)	PUNCT
aji-171	494	46	.	.	PUNCT
aji-171	495	1	delivering	deliver	VERB
aji-171	495	2	precision	precision	NOUN
aji-171	495	3	oncology	oncology	NOUN
aji-171	495	4	to	to	ADP
aji-171	495	5	patients	patient	NOUN
aji-171	495	6	with	with	ADP
aji-171	495	7	cancer	cancer	NOUN
aji-171	495	8	.	.	PUNCT
aji-171	496	1	nature	nature	NOUN
aji-171	496	2	medicine	medicine	NOUN
aji-171	496	3	,	,	PUNCT
aji-171	496	4	28	28	NUM
aji-171	496	5	,	,	PUNCT
aji-171	496	6	658–665	658–665	NUM
aji-171	496	7	.	.	PUNCT
aji-171	497	1	millard	millard	PROPN
aji-171	497	2	,	,	PUNCT
aji-171	497	3	h.	h.	PROPN
aji-171	497	4	r.	r.	PROPN
aji-171	497	5	,	,	PUNCT
aji-171	497	6	musani	musani	PROPN
aji-171	497	7	,	,	PUNCT
aji-171	497	8	s.	s.	PROPN
aji-171	497	9	k.	k.	PROPN
aji-171	497	10	,	,	PUNCT
aji-171	497	11	dibaba	dibaba	PROPN
aji-171	497	12	,	,	PUNCT
aji-171	497	13	d.	d.	PROPN
aji-171	497	14	t.	t.	PROPN
aji-171	497	15	,	,	PUNCT
aji-171	497	16	talegawkar	talegawkar	PROPN
aji-171	497	17	,	,	PUNCT
aji-171	497	18	s.	s.	PROPN
aji-171	497	19	a.	a.	PROPN
aji-171	497	20	,	,	PUNCT
aji-171	497	21	taylor	taylor	PROPN
aji-171	497	22	,	,	PUNCT
aji-171	497	23	h.	h.	PROPN
aji-171	497	24	a.	a.	PROPN
aji-171	497	25	,	,	PUNCT
aji-171	497	26	tucker	tucker	PROPN
aji-171	497	27	,	,	PUNCT
aji-171	497	28	k.	k.	PROPN
aji-171	497	29	l.	l.	PROPN
aji-171	497	30	,	,	PUNCT
aji-171	497	31	&	&	CCONJ
aji-171	497	32	bidulescu	bidulescu	PROPN
aji-171	497	33	,	,	PUNCT
aji-171	497	34	a.	a.	NOUN
aji-171	497	35	(	(	PUNCT
aji-171	497	36	2018	2018	NUM
aji-171	497	37	)	)	PUNCT
aji-171	497	38	.	.	PUNCT
aji-171	498	1	dietary	dietary	ADJ
aji-171	498	2	choline	choline	NOUN
aji-171	498	3	and	and	CCONJ
aji-171	498	4	betaine	betaine	NOUN
aji-171	498	5	;	;	PUNCT
aji-171	498	6	associations	association	NOUN
aji-171	498	7	with	with	ADP
aji-171	498	8	subclinical	subclinical	ADJ
aji-171	498	9	markers	marker	NOUN
aji-171	498	10	of	of	ADP
aji-171	498	11	cardiovascular	cardiovascular	ADJ
aji-171	498	12	disease	disease	NOUN
aji-171	498	13	risk	risk	NOUN
aji-171	498	14	and	and	CCONJ
aji-171	498	15	incidence	incidence	NOUN
aji-171	498	16	of	of	ADP
aji-171	498	17	cvd	cvd	PROPN
aji-171	498	18	,	,	PUNCT
aji-171	498	19	coronary	coronary	ADJ
aji-171	498	20	heart	heart	NOUN
aji-171	498	21	disease	disease	NOUN
aji-171	498	22	and	and	CCONJ
aji-171	498	23	stroke	stroke	NOUN
aji-171	498	24	:	:	PUNCT
aji-171	498	25	the	the	DET
aji-171	498	26	jackson	jackson	PROPN
aji-171	498	27	heart	heart	PROPN
aji-171	498	28	study	study	PROPN
aji-171	498	29	.	.	PUNCT
aji-171	499	1	european	european	PROPN
aji-171	499	2	journal	journal	PROPN
aji-171	499	3	of	of	ADP
aji-171	499	4	nutrition	nutrition	PROPN
aji-171	499	5	,	,	PUNCT
aji-171	499	6	57	57	NUM
aji-171	499	7	,	,	PUNCT
aji-171	499	8	51–60	51–60	PROPN
aji-171	499	9	.	.	PUNCT
aji-171	500	1	miller	miller	PROPN
aji-171	500	2	,	,	PUNCT
aji-171	500	3	j.	j.	PROPN
aji-171	500	4	j.	j.	PROPN
aji-171	500	5	,	,	PUNCT
aji-171	500	6	gonzalez	gonzalez	PROPN
aji-171	500	7	castro	castro	PROPN
aji-171	500	8	,	,	PUNCT
aji-171	500	9	l.	l.	PROPN
aji-171	500	10	n.	n.	PROPN
aji-171	500	11	,	,	PUNCT
aji-171	500	12	mcbrayer	mcbrayer	PROPN
aji-171	500	13	,	,	PUNCT
aji-171	500	14	s.	s.	PROPN
aji-171	500	15	,	,	PUNCT
aji-171	500	16	weller	weller	NOUN
aji-171	500	17	,	,	PUNCT
aji-171	500	18	m.	m.	NOUN
aji-171	500	19	,	,	PUNCT
aji-171	500	20	cloughesy	cloughesy	ADJ
aji-171	500	21	,	,	PUNCT
aji-171	500	22	t.	t.	PROPN
aji-171	500	23	,	,	PUNCT
aji-171	500	24	portnow	portnow	PROPN
aji-171	500	25	,	,	PUNCT
aji-171	500	26	j.	j.	PROPN
aji-171	500	27	,	,	PUNCT
aji-171	500	28	andronesi	andronesi	PROPN
aji-171	500	29	,	,	PUNCT
aji-171	500	30	o.	o.	PROPN
aji-171	500	31	,	,	PUNCT
aji-171	500	32	barnholtz	barnholtz	NOUN
aji-171	500	33	-	-	PUNCT
aji-171	500	34	sloan	sloan	PROPN
aji-171	500	35	,	,	PUNCT
aji-171	500	36	j.	j.	PROPN
aji-171	500	37	s.	s.	PROPN
aji-171	500	38	,	,	PUNCT
aji-171	500	39	baumert	baumert	PROPN
aji-171	500	40	,	,	PUNCT
aji-171	500	41	b.	b.	PROPN
aji-171	500	42	g.	g.	PROPN
aji-171	500	43	,	,	PUNCT
aji-171	500	44	&	&	CCONJ
aji-171	500	45	berger	berger	PROPN
aji-171	500	46	,	,	PUNCT
aji-171	500	47	m.	m.	PROPN
aji-171	500	48	s.	s.	PROPN
aji-171	500	49	(	(	PUNCT
aji-171	500	50	2023	2023	NUM
aji-171	500	51	)	)	PUNCT
aji-171	500	52	.	.	PUNCT
aji-171	501	1	isocitrate	isocitrate	ADJ
aji-171	501	2	dehydrogenase	dehydrogenase	NOUN
aji-171	501	3	(	(	PUNCT
aji-171	501	4	idh	idh	NOUN
aji-171	501	5	)	)	PUNCT
aji-171	501	6	mutant	mutant	NOUN
aji-171	501	7	gliomas	glioma	NOUN
aji-171	501	8	:	:	PUNCT
aji-171	501	9	a	a	DET
aji-171	501	10	society	society	NOUN
aji-171	501	11	for	for	ADP
aji-171	501	12	neuro	neuro	NOUN
aji-171	501	13	-	-	PUNCT
aji-171	501	14	oncology	oncology	NOUN
aji-171	501	15	(	(	PUNCT
aji-171	501	16	sno	sno	NOUN
aji-171	501	17	)	)	PUNCT
aji-171	501	18	consensus	consensus	NOUN
aji-171	501	19	review	review	NOUN
aji-171	501	20	on	on	ADP
aji-171	501	21	diagnosis	diagnosis	NOUN
aji-171	501	22	,	,	PUNCT
aji-171	501	23	management	management	NOUN
aji-171	501	24	,	,	PUNCT
aji-171	501	25	and	and	CCONJ
aji-171	501	26	future	future	ADJ
aji-171	501	27	directions	direction	NOUN
aji-171	501	28	.	.	PUNCT
aji-171	502	1	neurooncology	neurooncology	NOUN
aji-171	502	2	,	,	PUNCT
aji-171	502	3	25	25	NUM
aji-171	502	4	,	,	PUNCT
aji-171	502	5	4–25	4–25	NOUN
aji-171	502	6	.	.	PUNCT
aji-171	503	1	moncrieff	moncrieff	PROPN
aji-171	503	2	,	,	PUNCT
aji-171	503	3	j.	j.	PROPN
aji-171	503	4	,	,	PUNCT
aji-171	503	5	cooper	cooper	PROPN
aji-171	503	6	,	,	PUNCT
aji-171	503	7	r.	r.	PROPN
aji-171	503	8	e.	e.	PROPN
aji-171	503	9	,	,	PUNCT
aji-171	503	10	stockmann	stockmann	PROPN
aji-171	503	11	,	,	PUNCT
aji-171	503	12	t.	t.	PROPN
aji-171	503	13	,	,	PUNCT
aji-171	503	14	amendola	amendola	PROPN
aji-171	503	15	,	,	PUNCT
aji-171	503	16	s.	s.	PROPN
aji-171	503	17	,	,	PUNCT
aji-171	503	18	hengartner	hengartner	NOUN
aji-171	503	19	,	,	PUNCT
aji-171	503	20	m.	m.	NOUN
aji-171	503	21	p.	p.	PROPN
aji-171	503	22	,	,	PUNCT
aji-171	503	23	&	&	CCONJ
aji-171	503	24	horowitz	horowitz	PROPN
aji-171	503	25	,	,	PUNCT
aji-171	503	26	m.	m.	NOUN
aji-171	503	27	a.	a.	NOUN
aji-171	503	28	(	(	PUNCT
aji-171	503	29	2023	2023	NUM
aji-171	503	30	)	)	PUNCT
aji-171	503	31	.	.	PUNCT
aji-171	504	1	the	the	DET
aji-171	504	2	serotonin	serotonin	NOUN
aji-171	504	3	theory	theory	NOUN
aji-171	504	4	of	of	ADP
aji-171	504	5	depression	depression	NOUN
aji-171	504	6	:	:	PUNCT
aji-171	504	7	a	a	DET
aji-171	504	8	systematic	systematic	ADJ
aji-171	504	9	umbrella	umbrella	NOUN
aji-171	504	10	review	review	NOUN
aji-171	504	11	of	of	ADP
aji-171	504	12	the	the	DET
aji-171	504	13	evidence	evidence	NOUN
aji-171	504	14	.	.	PUNCT
aji-171	505	1	molecular	molecular	ADJ
aji-171	505	2	psychiatry	psychiatry	NOUN
aji-171	505	3	,	,	PUNCT
aji-171	505	4	28	28	NUM
aji-171	505	5	,	,	PUNCT
aji-171	505	6	3243–3256	3243–3256	NUM
aji-171	505	7	.	.	PUNCT
aji-171	506	1	mor	mor	PROPN
aji-171	506	2	,	,	PUNCT
aji-171	506	3	a.	a.	NOUN
aji-171	506	4	,	,	PUNCT
aji-171	506	5	tankiewicz	tankiewicz	NOUN
aji-171	506	6	-	-	PUNCT
aji-171	506	7	kwedlo	kwedlo	NOUN
aji-171	506	8	,	,	PUNCT
aji-171	506	9	a.	a.	NOUN
aji-171	506	10	,	,	PUNCT
aji-171	506	11	krupa	krupa	PROPN
aji-171	506	12	,	,	PUNCT
aji-171	506	13	a.	a.	PROPN
aji-171	506	14	,	,	PUNCT
aji-171	506	15	&	&	CCONJ
aji-171	506	16	pawlak	pawlak	PROPN
aji-171	506	17	,	,	PUNCT
aji-171	506	18	d.	d.	PROPN
aji-171	506	19	(	(	PUNCT
aji-171	506	20	2021	2021	NUM
aji-171	506	21	)	)	PUNCT
aji-171	506	22	.	.	PUNCT
aji-171	507	1	role	role	NOUN
aji-171	507	2	of	of	ADP
aji-171	507	3	kynurenine	kynurenine	NOUN
aji-171	507	4	pathway	pathway	NOUN
aji-171	507	5	in	in	ADP
aji-171	507	6	oxidative	oxidative	ADJ
aji-171	507	7	stress	stress	NOUN
aji-171	507	8	during	during	ADP
aji-171	507	9	neurodegenerative	neurodegenerative	ADJ
aji-171	507	10	disorders	disorder	NOUN
aji-171	507	11	.	.	PUNCT
aji-171	508	1	cells	cell	NOUN
aji-171	508	2	,	,	PUNCT
aji-171	508	3	10	10	NUM
aji-171	508	4	,	,	PUNCT
aji-171	508	5	1603	1603	NUM
aji-171	508	6	.	.	PUNCT
aji-171	509	1	mullen	mullen	PROPN
aji-171	509	2	,	,	PUNCT
aji-171	509	3	n.	n.	PROPN
aji-171	509	4	j.	j.	PROPN
aji-171	509	5	,	,	PUNCT
aji-171	509	6	&	&	CCONJ
aji-171	509	7	singh	singh	PROPN
aji-171	509	8	,	,	PUNCT
aji-171	509	9	p.	p.	PROPN
aji-171	509	10	k.	k.	PROPN
aji-171	510	1	(	(	PUNCT
aji-171	510	2	2023	2023	NUM
aji-171	510	3	)	)	PUNCT
aji-171	510	4	.	.	PUNCT
aji-171	511	1	nucleotide	nucleotide	ADJ
aji-171	511	2	metabolism	metabolism	NOUN
aji-171	511	3	:	:	PUNCT
aji-171	511	4	a	a	DET
aji-171	511	5	pan	pan	ADJ
aji-171	511	6	-	-	ADJ
aji-171	511	7	cancer	cancer	ADJ
aji-171	511	8	metabolic	metabolic	NOUN
aji-171	511	9	dependency	dependency	NOUN
aji-171	511	10	.	.	PUNCT
aji-171	512	1	nature	nature	NOUN
aji-171	512	2	review	review	NOUN
aji-171	512	3	on	on	ADP
aji-171	512	4	cancer	cancer	NOUN
aji-171	512	5	,	,	PUNCT
aji-171	512	6	23	23	NUM
aji-171	512	7	,	,	PUNCT
aji-171	512	8	275–294	275–294	NUM
aji-171	512	9	.	.	PUNCT
aji-171	513	1	neergaard	neergaard	PROPN
aji-171	513	2	,	,	PUNCT
aji-171	513	3	j.	j.	PROPN
aji-171	513	4	s.	s.	PROPN
aji-171	513	5	,	,	PUNCT
aji-171	513	6	dragsbæk	dragsbæk	PROPN
aji-171	513	7	,	,	PUNCT
aji-171	513	8	k.	k.	PROPN
aji-171	513	9	,	,	PUNCT
aji-171	513	10	christiansen	christiansen	PROPN
aji-171	513	11	,	,	PUNCT
aji-171	513	12	c.	c.	PROPN
aji-171	513	13	,	,	PUNCT
aji-171	513	14	nielsen	nielsen	PROPN
aji-171	513	15	,	,	PUNCT
aji-171	513	16	h.	h.	PROPN
aji-171	513	17	b.	b.	PROPN
aji-171	513	18	,	,	PUNCT
aji-171	513	19	brix	brix	NOUN
aji-171	513	20	,	,	PUNCT
aji-171	513	21	s.	s.	PROPN
aji-171	513	22	,	,	PUNCT
aji-171	513	23	&	&	CCONJ
aji-171	513	24	karsdal	karsdal	ADJ
aji-171	513	25	,	,	PUNCT
aji-171	513	26	m.	m.	NOUN
aji-171	513	27	a.	a.	NOUN
aji-171	513	28	(	(	PUNCT
aji-171	513	29	2017	2017	NUM
aji-171	513	30	)	)	PUNCT
aji-171	513	31	.	.	PUNCT
aji-171	514	1	henriksen	henriksen	PROPN
aji-171	514	2	,	,	PUNCT
aji-171	514	3	k.	k.	PROPN
aji-171	514	4	metabolic	metabolic	PROPN
aji-171	514	5	syndrome	syndrome	PROPN
aji-171	514	6	,	,	PUNCT
aji-171	514	7	insulin	insulin	NOUN
aji-171	514	8	resistance	resistance	NOUN
aji-171	514	9	,	,	PUNCT
aji-171	514	10	and	and	CCONJ
aji-171	514	11	cognitive	cognitive	ADJ
aji-171	514	12	dysfunction	dysfunction	NOUN
aji-171	514	13	:	:	PUNCT
aji-171	514	14	does	do	AUX
aji-171	514	15	your	your	PRON
aji-171	514	16	metabolic	metabolic	NOUN
aji-171	514	17	profile	profile	NOUN
aji-171	514	18	affect	affect	VERB
aji-171	514	19	your	your	PRON
aji-171	514	20	brain	brain	NOUN
aji-171	514	21	?	?	PUNCT
aji-171	515	1	diabetes	diabetes	NOUN
aji-171	515	2	,	,	PUNCT
aji-171	515	3	66	66	NUM
aji-171	515	4	,	,	PUNCT
aji-171	515	5	1957	1957	NUM
aji-171	515	6	–	–	PUNCT
aji-171	515	7	1963	1963	NUM
aji-171	515	8	.	.	PUNCT
aji-171	516	1	nielsen	nielsen	PROPN
aji-171	516	2	,	,	PUNCT
aji-171	516	3	j.	j.	PROPN
aji-171	516	4	(	(	PUNCT
aji-171	516	5	2017	2017	NUM
aji-171	516	6	)	)	PUNCT
aji-171	516	7	.	.	PUNCT
aji-171	517	1	systems	system	NOUN
aji-171	517	2	biology	biology	NOUN
aji-171	517	3	of	of	ADP
aji-171	517	4	metabolism	metabolism	NOUN
aji-171	517	5	:	:	PUNCT
aji-171	517	6	a	a	DET
aji-171	517	7	driver	driver	NOUN
aji-171	517	8	for	for	ADP
aji-171	517	9	developing	develop	VERB
aji-171	517	10	personalized	personalize	VERB
aji-171	517	11	and	and	CCONJ
aji-171	517	12	precision	precision	NOUN
aji-171	517	13	medicine	medicine	NOUN
aji-171	517	14	.	.	PUNCT
aji-171	518	1	cell	cell	NOUN
aji-171	518	2	metabolism	metabolism	NOUN
aji-171	518	3	,	,	PUNCT
aji-171	518	4	25	25	NUM
aji-171	518	5	,	,	PUNCT
aji-171	518	6	572–579	572–579	NUM
aji-171	518	7	.	.	PUNCT
aji-171	519	1	nikou	nikou	PROPN
aji-171	519	2	,	,	PUNCT
aji-171	519	3	t.	t.	PROPN
aji-171	519	4	,	,	PUNCT
aji-171	519	5	witt	witt	PROPN
aji-171	519	6	,	,	PUNCT
aji-171	519	7	m.	m.	NOUN
aji-171	519	8	,	,	PUNCT
aji-171	519	9	stathopoulos	stathopoulo	NOUN
aji-171	519	10	,	,	PUNCT
aji-171	519	11	p.	p.	PROPN
aji-171	519	12	,	,	PUNCT
aji-171	519	13	barsch	barsch	PROPN
aji-171	519	14	,	,	PUNCT
aji-171	519	15	a.	a.	PROPN
aji-171	519	16	,	,	PUNCT
aji-171	519	17	&	&	CCONJ
aji-171	519	18	halabalaki	halabalaki	PROPN
aji-171	519	19	,	,	PUNCT
aji-171	519	20	m.	m.	NOUN
aji-171	519	21	(	(	PUNCT
aji-171	519	22	2020	2020	NUM
aji-171	519	23	)	)	PUNCT
aji-171	519	24	.	.	PUNCT
aji-171	520	1	olive	olive	ADJ
aji-171	520	2	oil	oil	NOUN
aji-171	520	3	quality	quality	NOUN
aji-171	520	4	and	and	CCONJ
aji-171	520	5	authenticity	authenticity	NOUN
aji-171	520	6	assessment	assessment	NOUN
aji-171	520	7	aspects	aspect	NOUN
aji-171	520	8	employing	employ	VERB
aji-171	520	9	fia	fia	PROPN
aji-171	520	10	-	-	PUNCT
aji-171	520	11	mrms	mrm	NOUN
aji-171	520	12	and	and	CCONJ
aji-171	520	13	lc	lc	NOUN
aji-171	520	14	-	-	PUNCT
aji-171	520	15	orbitrap	orbitrap	NOUN
aji-171	520	16	ms	ms	NOUN
aji-171	520	17	metabolomic	metabolomic	ADJ
aji-171	520	18	approaches	approach	NOUN
aji-171	520	19	.	.	PUNCT
aji-171	521	1	frontiers	frontier	NOUN
aji-171	521	2	in	in	ADP
aji-171	521	3	public	public	ADJ
aji-171	521	4	health	health	NOUN
aji-171	521	5	,	,	PUNCT
aji-171	521	6	8	8	NUM
aji-171	521	7	,	,	PUNCT
aji-171	521	8	558226	558226	NUM
aji-171	521	9	.	.	PUNCT
aji-171	522	1	https://doi.org/10.3389/fpubh.2020.558226	https://doi.org/10.3389/fpubh.2020.558226	PROPN
aji-171	522	2	o’farrell	o’farrell	VERB
aji-171	522	3	,	,	PUNCT
aji-171	522	4	k.	k.	PROPN
aji-171	522	5	,	,	PUNCT
aji-171	522	6	&	&	CCONJ
aji-171	522	7	harkin	harkin	X
aji-171	522	8	,	,	PUNCT
aji-171	522	9	a.	a.	NOUN
aji-171	522	10	(	(	PUNCT
aji-171	522	11	2017	2017	NUM
aji-171	522	12	)	)	PUNCT
aji-171	522	13	.	.	PUNCT
aji-171	523	1	stress	stress	NOUN
aji-171	523	2	-	-	PUNCT
aji-171	523	3	related	relate	VERB
aji-171	523	4	regulation	regulation	NOUN
aji-171	523	5	of	of	ADP
aji-171	523	6	the	the	DET
aji-171	523	7	kynurenine	kynurenine	NOUN
aji-171	523	8	pathway	pathway	NOUN
aji-171	523	9	:	:	PUNCT
aji-171	523	10	relevance	relevance	NOUN
aji-171	523	11	to	to	ADP
aji-171	523	12	neuropsychiatric	neuropsychiatric	ADJ
aji-171	523	13	and	and	CCONJ
aji-171	523	14	degenerative	degenerative	ADJ
aji-171	523	15	disorders	disorder	NOUN
aji-171	523	16	.	.	PUNCT
aji-171	524	1	neuropharmacology	neuropharmacology	NOUN
aji-171	524	2	,	,	PUNCT
aji-171	524	3	112	112	NUM
aji-171	524	4	,	,	PUNCT
aji-171	524	5	307–323	307–323	NUM
aji-171	524	6	.	.	PUNCT
aji-171	525	1	o’riordan	o’riordan	PROPN
aji-171	525	2	,	,	PUNCT
aji-171	525	3	k.	k.	PROPN
aji-171	525	4	j.	j.	PROPN
aji-171	525	5	,	,	PUNCT
aji-171	525	6	collins	collins	PROPN
aji-171	525	7	,	,	PUNCT
aji-171	525	8	m.	m.	PROPN
aji-171	525	9	k.	k.	PROPN
aji-171	525	10	,	,	PUNCT
aji-171	525	11	moloney	moloney	PROPN
aji-171	525	12	,	,	PUNCT
aji-171	525	13	g.	g.	PROPN
aji-171	525	14	m.	m.	PROPN
aji-171	525	15	,	,	PUNCT
aji-171	525	16	knox	knox	PROPN
aji-171	525	17	,	,	PUNCT
aji-171	525	18	e.	e.	PROPN
aji-171	525	19	g.	g.	PROPN
aji-171	525	20	,	,	PUNCT
aji-171	525	21	aburto	aburto	NOUN
aji-171	525	22	,	,	PUNCT
aji-171	525	23	m.	m.	NOUN
aji-171	525	24	r.	r.	PROPN
aji-171	525	25	,	,	PUNCT
aji-171	525	26	fülling	fülling	NOUN
aji-171	525	27	,	,	PUNCT
aji-171	525	28	c.	c.	NOUN
aji-171	525	29	,	,	PUNCT
aji-171	525	30	morley	morley	PROPN
aji-171	525	31	,	,	PUNCT
aji-171	525	32	s.	s.	PROPN
aji-171	525	33	j.	j.	PROPN
aji-171	525	34	,	,	PUNCT
aji-171	525	35	clarke	clarke	PROPN
aji-171	525	36	,	,	PUNCT
aji-171	525	37	g.	g.	PROPN
aji-171	525	38	,	,	PUNCT
aji-171	525	39	schellekens	schellekens	PROPN
aji-171	525	40	,	,	PUNCT
aji-171	525	41	h.	h.	PROPN
aji-171	525	42	,	,	PUNCT
aji-171	525	43	&	&	CCONJ
aji-171	525	44	cryan	cryan	PROPN
aji-171	525	45	,	,	PUNCT
aji-171	525	46	j.	j.	PROPN
aji-171	525	47	f.	f.	PROPN
aji-171	525	48	(	(	PUNCT
aji-171	525	49	2022	2022	NUM
aji-171	525	50	)	)	PUNCT
aji-171	525	51	.	.	PUNCT
aji-171	526	1	short	short	ADJ
aji-171	526	2	chain	chain	NOUN
aji-171	526	3	fatty	fatty	NOUN
aji-171	526	4	acids	acid	NOUN
aji-171	526	5	:	:	PUNCT
aji-171	526	6	microbial	microbial	ADJ
aji-171	526	7	metabolites	metabolite	NOUN
aji-171	526	8	for	for	ADP
aji-171	526	9	gut	gut	NOUN
aji-171	526	10	-	-	PUNCT
aji-171	526	11	brain	brain	NOUN
aji-171	526	12	axis	axis	NOUN
aji-171	526	13	signalling	signal	VERB
aji-171	526	14	.	.	PUNCT
aji-171	527	1	molecular	molecular	ADJ
aji-171	527	2	and	and	CCONJ
aji-171	527	3	cellular	cellular	ADJ
aji-171	527	4	endocrinology	endocrinology	NOUN
aji-171	527	5	journal	journal	NOUN
aji-171	527	6	,	,	PUNCT
aji-171	527	7	546	546	NUM
aji-171	527	8	,	,	PUNCT
aji-171	527	9	111572	111572	NUM
aji-171	527	10	.	.	PUNCT
aji-171	527	11	odom	odom	PROPN
aji-171	527	12	,	,	PUNCT
aji-171	527	13	j.	j.	PROPN
aji-171	527	14	d.	d.	PROPN
aji-171	527	15	,	,	PUNCT
aji-171	527	16	&	&	CCONJ
aji-171	527	17	sutton	sutton	PROPN
aji-171	527	18	,	,	PUNCT
aji-171	527	19	v.	v.	PROPN
aji-171	527	20	r.	r.	PROPN
aji-171	527	21	(	(	PUNCT
aji-171	527	22	2021	2021	NUM
aji-171	527	23	)	)	PUNCT
aji-171	527	24	.	.	PUNCT
aji-171	528	1	metabolomics	metabolomic	NOUN
aji-171	528	2	in	in	ADP
aji-171	528	3	clinical	clinical	ADJ
aji-171	528	4	practice	practice	NOUN
aji-171	528	5	:	:	PUNCT
aji-171	528	6	improving	improve	VERB
aji-171	528	7	diagnosis	diagnosis	NOUN
aji-171	528	8	and	and	CCONJ
aji-171	528	9	informing	inform	VERB
aji-171	528	10	management	management	NOUN
aji-171	528	11	.	.	PUNCT
aji-171	529	1	clinical	clinical	ADJ
aji-171	529	2	chemistry	chemistry	NOUN
aji-171	529	3	,	,	PUNCT
aji-171	529	4	67	67	NUM
aji-171	529	5	,	,	PUNCT
aji-171	529	6	1606–1617	1606–1617	NUM
aji-171	529	7	.	.	PUNCT
aji-171	529	8	ou	ou	PROPN
aji-171	529	9	,	,	PUNCT
aji-171	529	10	q.	q.	PROPN
aji-171	529	11	,	,	PUNCT
aji-171	529	12	qiao	qiao	PROPN
aji-171	529	13	,	,	PUNCT
aji-171	529	14	x.	x.	PROPN
aji-171	529	15	,	,	PUNCT
aji-171	529	16	li	li	PROPN
aji-171	529	17	,	,	PUNCT
aji-171	529	18	z.	z.	PROPN
aji-171	529	19	,	,	PUNCT
aji-171	529	20	niu	niu	PROPN
aji-171	529	21	,	,	PUNCT
aji-171	529	22	l.	l.	PROPN
aji-171	529	23	,	,	PUNCT
aji-171	529	24	lei	lei	PROPN
aji-171	529	25	,	,	PUNCT
aji-171	529	26	f.	f.	PROPN
aji-171	529	27	,	,	PUNCT
aji-171	529	28	&	&	CCONJ
aji-171	529	29	cheng	cheng	PROPN
aji-171	529	30	,	,	PUNCT
aji-171	529	31	r.	r.	PROPN
aji-171	529	32	(	(	PUNCT
aji-171	529	33	2024	2024	NUM
aji-171	529	34	)	)	PUNCT
aji-171	529	35	.	.	PUNCT
aji-171	530	1	apoptosis	apoptosis	NOUN
aji-171	530	2	releases	release	VERB
aji-171	530	3	hydrogen	hydrogen	NOUN
aji-171	530	4	sulfide	sulfide	NOUN
aji-171	530	5	to	to	PART
aji-171	530	6	inhibit	inhibit	VERB
aji-171	530	7	th17	th17	PROPN
aji-171	530	8	cell	cell	NOUN
aji-171	530	9	differentiation	differentiation	NOUN
aji-171	530	10	.	.	PUNCT
aji-171	531	1	cell	cell	NOUN
aji-171	531	2	metabolism	metabolism	NOUN
aji-171	531	3	,	,	PUNCT
aji-171	531	4	36	36	NUM
aji-171	531	5	,	,	PUNCT
aji-171	531	6	78–89	78–89	NUM
aji-171	531	7	.	.	PUNCT
aji-171	532	1	mamman	mamman	NOUN
aji-171	532	2	et	et	PROPN
aji-171	532	3	al	al	PROPN
aji-171	532	4	.	.	PROPN
aji-171	532	5	;	;	PUNCT
aji-171	532	6	asian	asian	PROPN
aji-171	532	7	j.	j.	PROPN
aji-171	532	8	immunol	immunol	PROPN
aji-171	532	9	.	.	PROPN
aji-171	532	10	,	,	PUNCT
aji-171	532	11	vol	vol	NOUN
aji-171	532	12	.	.	PROPN
aji-171	532	13	8	8	NUM
aji-171	532	14	,	,	PUNCT
aji-171	532	15	no	no	INTJ
aji-171	532	16	.	.	NOUN
aji-171	532	17	1	1	NUM
aji-171	532	18	,	,	PUNCT
aji-171	532	19	pp	pp	ADJ
aji-171	532	20	.	.	PUNCT
aji-171	533	1	190	190	NUM
aji-171	533	2	-	-	SYM
aji-171	533	3	206	206	NUM
aji-171	533	4	,	,	PUNCT
aji-171	533	5	2025	2025	NUM
aji-171	533	6	;	;	PUNCT
aji-171	533	7	article	article	NOUN
aji-171	533	8	no.aji.140476	no.aji.140476	NOUN
aji-171	533	9	204	204	NUM
aji-171	533	10	park	park	NOUN
aji-171	533	11	,	,	PUNCT
aji-171	533	12	j.	j.	PROPN
aji-171	533	13	,	,	PUNCT
aji-171	533	14	miller	miller	PROPN
aji-171	533	15	,	,	PUNCT
aji-171	533	16	m.	m.	NOUN
aji-171	533	17	,	,	PUNCT
aji-171	533	18	rhyne	rhyne	PROPN
aji-171	533	19	,	,	PUNCT
aji-171	533	20	j.	j.	PROPN
aji-171	533	21	,	,	PUNCT
aji-171	533	22	wang	wang	PROPN
aji-171	533	23	,	,	PUNCT
aji-171	533	24	z.	z.	PROPN
aji-171	533	25	,	,	PUNCT
aji-171	533	26	&	&	CCONJ
aji-171	533	27	hazen	hazen	PROPN
aji-171	533	28	,	,	PUNCT
aji-171	533	29	s.	s.	PROPN
aji-171	533	30	(	(	PUNCT
aji-171	533	31	2019	2019	NUM
aji-171	533	32	)	)	PUNCT
aji-171	533	33	.	.	PUNCT
aji-171	534	1	differential	differential	ADJ
aji-171	534	2	effect	effect	NOUN
aji-171	534	3	of	of	ADP
aji-171	534	4	short	short	ADJ
aji-171	534	5	-	-	PUNCT
aji-171	534	6	term	term	NOUN
aji-171	534	7	popular	popular	ADJ
aji-171	534	8	diets	diet	NOUN
aji-171	534	9	on	on	ADP
aji-171	534	10	tmao	tmao	PROPN
aji-171	534	11	and	and	CCONJ
aji-171	534	12	other	other	ADJ
aji-171	534	13	cardiometabolic	cardiometabolic	PROPN
aji-171	534	14	risk	risk	NOUN
aji-171	534	15	markers	marker	NOUN
aji-171	534	16	.	.	PUNCT
aji-171	535	1	nutrition	nutrition	NOUN
aji-171	535	2	,	,	PUNCT
aji-171	535	3	metabolism	metabolism	NOUN
aji-171	535	4	and	and	CCONJ
aji-171	535	5	cardiovascular	cardiovascular	ADJ
aji-171	535	6	diseases	disease	NOUN
aji-171	535	7	,	,	PUNCT
aji-171	535	8	29	29	NUM
aji-171	535	9	,	,	PUNCT
aji-171	535	10	513–517	513–517	NUM
aji-171	535	11	.	.	PUNCT
aji-171	536	1	park	park	NOUN
aji-171	536	2	,	,	PUNCT
aji-171	536	3	s.	s.	PROPN
aji-171	536	4	,	,	PUNCT
aji-171	536	5	sadanala	sadanala	PROPN
aji-171	536	6	,	,	PUNCT
aji-171	536	7	k.	k.	PROPN
aji-171	536	8	c.	c.	PROPN
aji-171	536	9	,	,	PUNCT
aji-171	536	10	&	&	CCONJ
aji-171	536	11	kim	kim	PROPN
aji-171	536	12	,	,	PUNCT
aji-171	536	13	e.	e.	PROPN
aji-171	536	14	k.	k.	PROPN
aji-171	536	15	(	(	PUNCT
aji-171	536	16	2015	2015	NUM
aji-171	536	17	)	)	PUNCT
aji-171	536	18	.	.	PUNCT
aji-171	537	1	a	a	DET
aji-171	537	2	metabolomic	metabolomic	ADJ
aji-171	537	3	approach	approach	NOUN
aji-171	537	4	to	to	ADP
aji-171	537	5	understanding	understand	VERB
aji-171	537	6	the	the	DET
aji-171	537	7	metabolic	metabolic	NOUN
aji-171	537	8	link	link	NOUN
aji-171	537	9	between	between	ADP
aji-171	537	10	obesity	obesity	NOUN
aji-171	537	11	and	and	CCONJ
aji-171	537	12	diabetes	diabetes	NOUN
aji-171	537	13	.	.	PUNCT
aji-171	538	1	molecules	molecule	NOUN
aji-171	538	2	and	and	CCONJ
aji-171	538	3	cells	cell	NOUN
aji-171	538	4	,	,	PUNCT
aji-171	538	5	38	38	NUM
aji-171	538	6	,	,	PUNCT
aji-171	538	7	587	587	NUM
aji-171	538	8	–	–	PUNCT
aji-171	538	9	596	596	NUM
aji-171	538	10	.	.	PUNCT
aji-171	539	1	parvanovova	parvanovova	PROPN
aji-171	539	2	,	,	PUNCT
aji-171	539	3	p.	p.	PROPN
aji-171	539	4	,	,	PUNCT
aji-171	539	5	hnilicova	hnilicova	PROPN
aji-171	539	6	,	,	PUNCT
aji-171	539	7	p.	p.	NOUN
aji-171	539	8	,	,	PUNCT
aji-171	539	9	kolisek	kolisek	PROPN
aji-171	539	10	,	,	PUNCT
aji-171	539	11	m.	m.	NOUN
aji-171	539	12	,	,	PUNCT
aji-171	539	13	tatarkova	tatarkova	PROPN
aji-171	539	14	,	,	PUNCT
aji-171	539	15	z.	z.	PROPN
aji-171	539	16	,	,	PUNCT
aji-171	539	17	halasova	halasova	PROPN
aji-171	539	18	,	,	PUNCT
aji-171	539	19	e.	e.	PROPN
aji-171	539	20	,	,	PUNCT
aji-171	539	21	kurca	kurca	PROPN
aji-171	539	22	,	,	PUNCT
aji-171	539	23	e.	e.	PROPN
aji-171	539	24	,	,	PUNCT
aji-171	539	25	holubcikova	holubcikova	PROPN
aji-171	539	26	,	,	PUNCT
aji-171	539	27	s.	s.	PROPN
aji-171	539	28	,	,	PUNCT
aji-171	539	29	koprusakova	koprusakova	PROPN
aji-171	539	30	,	,	PUNCT
aji-171	539	31	m.	m.	NOUN
aji-171	539	32	t.	t.	PROPN
aji-171	539	33	,	,	PUNCT
aji-171	539	34	&	&	CCONJ
aji-171	539	35	baranovicova	baranovicova	PROPN
aji-171	539	36	,	,	PUNCT
aji-171	539	37	e.	e.	PROPN
aji-171	539	38	(	(	PUNCT
aji-171	539	39	2024	2024	NUM
aji-171	539	40	)	)	PUNCT
aji-171	539	41	.	.	PUNCT
aji-171	540	1	disturbances	disturbance	NOUN
aji-171	540	2	in	in	ADP
aji-171	540	3	muscle	muscle	NOUN
aji-171	540	4	energy	energy	NOUN
aji-171	540	5	metabolism	metabolism	NOUN
aji-171	540	6	in	in	ADP
aji-171	540	7	patients	patient	NOUN
aji-171	540	8	with	with	ADP
aji-171	540	9	amyotrophic	amyotrophic	ADJ
aji-171	540	10	lateral	lateral	ADJ
aji-171	540	11	sclerosis	sclerosis	NOUN
aji-171	540	12	.	.	PUNCT
aji-171	541	1	metabolites	metabolite	NOUN
aji-171	541	2	,	,	PUNCT
aji-171	541	3	14	14	NUM
aji-171	541	4	,	,	PUNCT
aji-171	541	5	356	356	NUM
aji-171	541	6	.	.	PUNCT
aji-171	542	1	pennisi	pennisi	VERB
aji-171	542	2	,	,	PUNCT
aji-171	542	3	m.	m.	NOUN
aji-171	542	4	,	,	PUNCT
aji-171	542	5	lanza	lanza	PROPN
aji-171	542	6	,	,	PUNCT
aji-171	542	7	g.	g.	PROPN
aji-171	542	8	,	,	PUNCT
aji-171	542	9	cantone	cantone	NOUN
aji-171	542	10	,	,	PUNCT
aji-171	542	11	m.	m.	NOUN
aji-171	542	12	,	,	PUNCT
aji-171	542	13	d’amico	d’amico	PROPN
aji-171	542	14	,	,	PUNCT
aji-171	542	15	e.	e.	PROPN
aji-171	542	16	,	,	PUNCT
aji-171	542	17	fisicaro	fisicaro	PROPN
aji-171	542	18	,	,	PUNCT
aji-171	542	19	f.	f.	PROPN
aji-171	542	20	,	,	PUNCT
aji-171	542	21	puglisi	puglisi	VERB
aji-171	542	22	,	,	PUNCT
aji-171	542	23	v.	v.	ADV
aji-171	542	24	,	,	PUNCT
aji-171	542	25	vinciguerra	vinciguerra	NOUN
aji-171	542	26	,	,	PUNCT
aji-171	542	27	l.	l.	PROPN
aji-171	542	28	,	,	PUNCT
aji-171	542	29	bella	bella	PROPN
aji-171	542	30	,	,	PUNCT
aji-171	542	31	r.	r.	PROPN
aji-171	542	32	,	,	PUNCT
aji-171	542	33	vicari	vicari	PROPN
aji-171	542	34	,	,	PUNCT
aji-171	542	35	e.	e.	PROPN
aji-171	542	36	,	,	PUNCT
aji-171	542	37	&	&	CCONJ
aji-171	542	38	malaguarnera	malaguarnera	PROPN
aji-171	542	39	,	,	PUNCT
aji-171	542	40	g.	g.	PROPN
aji-171	542	41	(	(	PUNCT
aji-171	542	42	2020	2020	NUM
aji-171	542	43	)	)	PUNCT
aji-171	542	44	.	.	PUNCT
aji-171	543	1	acetyl	acetyl	NOUN
aji-171	543	2	-	-	PUNCT
aji-171	543	3	l	l	NOUN
aji-171	543	4	-	-	NOUN
aji-171	543	5	carnitine	carnitine	NOUN
aji-171	543	6	in	in	ADP
aji-171	543	7	dementia	dementia	NOUN
aji-171	543	8	and	and	CCONJ
aji-171	543	9	other	other	ADJ
aji-171	543	10	cognitive	cognitive	ADJ
aji-171	543	11	disorders	disorder	NOUN
aji-171	543	12	:	:	PUNCT
aji-171	543	13	a	a	DET
aji-171	543	14	critical	critical	ADJ
aji-171	543	15	update	update	NOUN
aji-171	543	16	.	.	PUNCT
aji-171	544	1	nutrients	nutrient	NOUN
aji-171	544	2	,	,	PUNCT
aji-171	544	3	12	12	NUM
aji-171	544	4	,	,	PUNCT
aji-171	544	5	1389	1389	NUM
aji-171	544	6	.	.	PUNCT
aji-171	545	1	prat	prat	PROPN
aji-171	545	2	,	,	PUNCT
aji-171	545	3	a.	a.	NOUN
aji-171	545	4	,	,	PUNCT
aji-171	545	5	chaudhury	chaudhury	PROPN
aji-171	545	6	,	,	PUNCT
aji-171	545	7	a.	a.	PROPN
aji-171	545	8	,	,	PUNCT
aji-171	545	9	solovieff	solovieff	PROPN
aji-171	545	10	,	,	PUNCT
aji-171	545	11	n.	n.	NOUN
aji-171	545	12	,	,	PUNCT
aji-171	545	13	paré	paré	PROPN
aji-171	545	14	,	,	PUNCT
aji-171	545	15	l.	l.	PROPN
aji-171	545	16	,	,	PUNCT
aji-171	545	17	martinez	martinez	PROPN
aji-171	545	18	,	,	PUNCT
aji-171	545	19	d.	d.	PROPN
aji-171	545	20	,	,	PUNCT
aji-171	545	21	chic	chic	ADJ
aji-171	545	22	,	,	PUNCT
aji-171	545	23	n.	n.	NOUN
aji-171	545	24	,	,	PUNCT
aji-171	545	25	martínez	martínez	NOUN
aji-171	545	26	-	-	PUNCT
aji-171	545	27	sáez	sáez	PROPN
aji-171	545	28	,	,	PUNCT
aji-171	545	29	o.	o.	PROPN
aji-171	545	30	,	,	PUNCT
aji-171	545	31	brasó	brasó	NOUN
aji-171	545	32	-	-	PUNCT
aji-171	545	33	maristany	maristany	NOUN
aji-171	545	34	,	,	PUNCT
aji-171	545	35	f.	f.	PROPN
aji-171	545	36	,	,	PUNCT
aji-171	545	37	lteif	lteif	PROPN
aji-171	545	38	,	,	PUNCT
aji-171	545	39	a.	a.	PROPN
aji-171	545	40	,	,	PUNCT
aji-171	545	41	&	&	CCONJ
aji-171	545	42	taran	taran	NOUN
aji-171	545	43	,	,	PUNCT
aji-171	545	44	t.	t.	PROPN
aji-171	545	45	(	(	PUNCT
aji-171	545	46	2021	2021	NUM
aji-171	545	47	)	)	PUNCT
aji-171	545	48	.	.	PUNCT
aji-171	546	1	correlative	correlative	ADJ
aji-171	546	2	biomarker	biomarker	NOUN
aji-171	546	3	analysis	analysis	NOUN
aji-171	546	4	of	of	ADP
aji-171	546	5	intrinsic	intrinsic	ADJ
aji-171	546	6	subtypes	subtype	NOUN
aji-171	546	7	and	and	CCONJ
aji-171	546	8	efficacy	efficacy	NOUN
aji-171	546	9	across	across	ADP
aji-171	546	10	the	the	DET
aji-171	546	11	monaleesa	monaleesa	PROPN
aji-171	546	12	phase	phase	PROPN
aji-171	546	13	iii	iii	NUM
aji-171	546	14	studies	study	NOUN
aji-171	546	15	.	.	PUNCT
aji-171	547	1	journal	journal	PROPN
aji-171	547	2	of	of	ADP
aji-171	547	3	clinical	clinical	ADJ
aji-171	547	4	oncology	oncology	NOUN
aji-171	547	5	,	,	PUNCT
aji-171	547	6	39	39	NUM
aji-171	547	7	,	,	PUNCT
aji-171	547	8	1458	1458	NUM
aji-171	547	9	–	–	PUNCT
aji-171	547	10	1467	1467	NUM
aji-171	547	11	.	.	PUNCT
aji-171	548	1	prévot	prévot	PROPN
aji-171	548	2	,	,	PUNCT
aji-171	548	3	t.	t.	PROPN
aji-171	548	4	,	,	PUNCT
aji-171	548	5	&	&	CCONJ
aji-171	548	6	sibille	sibille	PROPN
aji-171	548	7	,	,	PUNCT
aji-171	548	8	e.	e.	PROPN
aji-171	548	9	(	(	PUNCT
aji-171	548	10	2021	2021	NUM
aji-171	548	11	)	)	PUNCT
aji-171	548	12	.	.	PUNCT
aji-171	549	1	altered	alter	VERB
aji-171	549	2	gabamediated	gabamediate	VERB
aji-171	549	3	information	information	NOUN
aji-171	549	4	processing	processing	NOUN
aji-171	549	5	and	and	CCONJ
aji-171	549	6	cognitive	cognitive	ADJ
aji-171	549	7	dysfunctions	dysfunction	NOUN
aji-171	549	8	in	in	ADP
aji-171	549	9	depression	depression	NOUN
aji-171	549	10	and	and	CCONJ
aji-171	549	11	other	other	ADJ
aji-171	549	12	brain	brain	NOUN
aji-171	549	13	disorders	disorder	NOUN
aji-171	549	14	.	.	PUNCT
aji-171	550	1	molecular	molecular	ADJ
aji-171	550	2	psychiatry	psychiatry	NOUN
aji-171	550	3	,	,	PUNCT
aji-171	550	4	26	26	NUM
aji-171	550	5	,	,	PUNCT
aji-171	550	6	151–167	151–167	NUM
aji-171	550	7	.	.	PUNCT
aji-171	551	1	rabinowitz	rabinowitz	PROPN
aji-171	551	2	,	,	PUNCT
aji-171	551	3	j.	j.	PROPN
aji-171	551	4	d.	d.	PROPN
aji-171	551	5	,	,	PUNCT
aji-171	551	6	&	&	CCONJ
aji-171	551	7	enerbäck	enerbäck	PROPN
aji-171	551	8	,	,	PUNCT
aji-171	551	9	s.	s.	PROPN
aji-171	551	10	(	(	PUNCT
aji-171	551	11	2020	2020	NUM
aji-171	551	12	)	)	PUNCT
aji-171	551	13	.	.	PUNCT
aji-171	552	1	lactate	lactate	PROPN
aji-171	552	2	:	:	PUNCT
aji-171	552	3	the	the	DET
aji-171	552	4	ugly	ugly	ADJ
aji-171	552	5	duckling	duckling	NOUN
aji-171	552	6	of	of	ADP
aji-171	552	7	energy	energy	NOUN
aji-171	552	8	metabolism	metabolism	NOUN
aji-171	552	9	.	.	PUNCT
aji-171	553	1	nature	nature	NOUN
aji-171	553	2	metabolism	metabolism	NOUN
aji-171	553	3	,	,	PUNCT
aji-171	553	4	2	2	NUM
aji-171	553	5	,	,	PUNCT
aji-171	553	6	566	566	NUM
aji-171	553	7	–	–	PUNCT
aji-171	553	8	571	571	NUM
aji-171	553	9	.	.	PUNCT
aji-171	554	1	rakheja	rakheja	PROPN
aji-171	554	2	,	,	PUNCT
aji-171	554	3	d.	d.	PROPN
aji-171	554	4	,	,	PUNCT
aji-171	554	5	medeiros	medeiros	PROPN
aji-171	554	6	,	,	PUNCT
aji-171	554	7	l.	l.	PROPN
aji-171	554	8	j.	j.	PROPN
aji-171	554	9	,	,	PUNCT
aji-171	554	10	bevan	bevan	PROPN
aji-171	554	11	,	,	PUNCT
aji-171	554	12	s.	s.	PROPN
aji-171	554	13	,	,	PUNCT
aji-171	554	14	&	&	CCONJ
aji-171	554	15	chen	chen	PROPN
aji-171	554	16	,	,	PUNCT
aji-171	554	17	w.	w.	PROPN
aji-171	554	18	(	(	PUNCT
aji-171	554	19	2013	2013	NUM
aji-171	554	20	)	)	PUNCT
aji-171	554	21	.	.	PUNCT
aji-171	555	1	the	the	DET
aji-171	555	2	emerging	emerge	VERB
aji-171	555	3	role	role	NOUN
aji-171	555	4	of	of	ADP
aji-171	555	5	d-2hydroxyglutarate	d-2hydroxyglutarate	NOUN
aji-171	555	6	as	as	ADP
aji-171	555	7	an	an	DET
aji-171	555	8	oncometabolite	oncometabolite	NOUN
aji-171	555	9	in	in	ADP
aji-171	555	10	hematolymphoid	hematolymphoid	ADJ
aji-171	555	11	and	and	CCONJ
aji-171	555	12	central	central	ADJ
aji-171	555	13	nervous	nervous	ADJ
aji-171	555	14	system	system	NOUN
aji-171	555	15	neoplasms	neoplasm	NOUN
aji-171	555	16	.	.	PUNCT
aji-171	556	1	frontiers	frontier	NOUN
aji-171	556	2	in	in	ADP
aji-171	556	3	oncology	oncology	NOUN
aji-171	556	4	,	,	PUNCT
aji-171	556	5	3	3	NUM
aji-171	556	6	,	,	PUNCT
aji-171	556	7	169	169	NUM
aji-171	556	8	.	.	PUNCT
aji-171	556	9	reveglia	reveglia	PROPN
aji-171	556	10	,	,	PUNCT
aji-171	556	11	p.	p.	NOUN
aji-171	556	12	,	,	PUNCT
aji-171	556	13	paolillo	paolillo	PROPN
aji-171	556	14	,	,	PUNCT
aji-171	556	15	c.	c.	PROPN
aji-171	556	16	,	,	PUNCT
aji-171	556	17	angiolillo	angiolillo	PROPN
aji-171	556	18	,	,	PUNCT
aji-171	556	19	a.	a.	PROPN
aji-171	556	20	,	,	PUNCT
aji-171	556	21	ferretti	ferretti	PROPN
aji-171	556	22	,	,	PUNCT
aji-171	556	23	g.	g.	PROPN
aji-171	556	24	,	,	PUNCT
aji-171	556	25	angelico	angelico	PROPN
aji-171	556	26	,	,	PUNCT
aji-171	556	27	r.	r.	PROPN
aji-171	556	28	,	,	PUNCT
aji-171	556	29	sirabella	sirabella	PROPN
aji-171	556	30	,	,	PUNCT
aji-171	556	31	r.	r.	PROPN
aji-171	556	32	,	,	PUNCT
aji-171	556	33	corso	corso	PROPN
aji-171	556	34	,	,	PUNCT
aji-171	556	35	g.	g.	PROPN
aji-171	556	36	,	,	PUNCT
aji-171	556	37	matrone	matrone	NOUN
aji-171	556	38	,	,	PUNCT
aji-171	556	39	c.	c.	PROPN
aji-171	556	40	,	,	PUNCT
aji-171	556	41	&	&	CCONJ
aji-171	556	42	di	di	PROPN
aji-171	556	43	costanzo	costanzo	PROPN
aji-171	556	44	,	,	PUNCT
aji-171	556	45	a.	a.	NOUN
aji-171	556	46	(	(	PUNCT
aji-171	556	47	2023	2023	NUM
aji-171	556	48	)	)	PUNCT
aji-171	556	49	.	.	PUNCT
aji-171	557	1	a	a	DET
aji-171	557	2	targeted	target	VERB
aji-171	557	3	mass	mass	ADJ
aji-171	557	4	spectrometry	spectrometry	NOUN
aji-171	557	5	approach	approach	NOUN
aji-171	557	6	to	to	PART
aji-171	557	7	identify	identify	VERB
aji-171	557	8	peripheral	peripheral	ADJ
aji-171	557	9	changes	change	NOUN
aji-171	557	10	in	in	ADP
aji-171	557	11	metabolic	metabolic	NOUN
aji-171	557	12	pathways	pathway	NOUN
aji-171	557	13	of	of	ADP
aji-171	557	14	patients	patient	NOUN
aji-171	557	15	with	with	ADP
aji-171	557	16	alzheimer	alzheimer	PROPN
aji-171	557	17	’s	’s	PART
aji-171	557	18	disease	disease	NOUN
aji-171	557	19	.	.	PUNCT
aji-171	558	1	international	international	ADJ
aji-171	558	2	journal	journal	NOUN
aji-171	558	3	of	of	ADP
aji-171	558	4	molecular	molecular	ADJ
aji-171	558	5	sciences	science	NOUN
aji-171	558	6	,	,	PUNCT
aji-171	558	7	24	24	NUM
aji-171	558	8	,	,	PUNCT
aji-171	558	9	9736	9736	NUM
aji-171	558	10	.	.	PUNCT
aji-171	559	1	roszczyc	roszczyc	ADJ
aji-171	559	2	-	-	PUNCT
aji-171	559	3	owsiejczuk	owsiejczuk	NOUN
aji-171	559	4	,	,	PUNCT
aji-171	559	5	k.	k.	PROPN
aji-171	559	6	,	,	PUNCT
aji-171	559	7	&	&	CCONJ
aji-171	559	8	zabielski	zabielski	PROPN
aji-171	559	9	,	,	PUNCT
aji-171	559	10	p.	p.	NOUN
aji-171	559	11	(	(	PUNCT
aji-171	559	12	2021	2021	NUM
aji-171	559	13	)	)	PUNCT
aji-171	559	14	.	.	PUNCT
aji-171	560	1	sphingolipids	sphingolipid	NOUN
aji-171	560	2	as	as	ADP
aji-171	560	3	a	a	DET
aji-171	560	4	culprit	culprit	NOUN
aji-171	560	5	of	of	ADP
aji-171	560	6	mitochondrial	mitochondrial	ADJ
aji-171	560	7	dysfunction	dysfunction	NOUN
aji-171	560	8	in	in	ADP
aji-171	560	9	insulin	insulin	NOUN
aji-171	560	10	resistance	resistance	NOUN
aji-171	560	11	and	and	CCONJ
aji-171	560	12	type	type	NOUN
aji-171	560	13	2	2	NUM
aji-171	560	14	diabetes	diabetes	NOUN
aji-171	560	15	.	.	PUNCT
aji-171	561	1	frontier	frontier	NOUN
aji-171	561	2	endocrinology	endocrinology	NOUN
aji-171	561	3	,	,	PUNCT
aji-171	561	4	12	12	NUM
aji-171	561	5	,	,	PUNCT
aji-171	561	6	635175	635175	NUM
aji-171	561	7	.	.	PUNCT
aji-171	562	1	sacchet	sacchet	NOUN
aji-171	562	2	,	,	PUNCT
aji-171	562	3	m.	m.	PROPN
aji-171	562	4	d.	d.	PROPN
aji-171	562	5	,	,	PUNCT
aji-171	562	6	keshava	keshava	PROPN
aji-171	562	7	,	,	PUNCT
aji-171	562	8	p.	p.	PROPN
aji-171	562	9	,	,	PUNCT
aji-171	562	10	walsh	walsh	PROPN
aji-171	562	11	,	,	PUNCT
aji-171	562	12	s.	s.	PROPN
aji-171	562	13	w.	w.	PROPN
aji-171	562	14	,	,	PUNCT
aji-171	562	15	potash	potash	NOUN
aji-171	562	16	,	,	PUNCT
aji-171	562	17	r.	r.	PROPN
aji-171	562	18	m.	m.	PROPN
aji-171	562	19	,	,	PUNCT
aji-171	562	20	li	li	PROPN
aji-171	562	21	,	,	PUNCT
aji-171	562	22	m.	m.	NOUN
aji-171	562	23	,	,	PUNCT
aji-171	562	24	liu	liu	PROPN
aji-171	562	25	,	,	PUNCT
aji-171	562	26	h.	h.	PROPN
aji-171	562	27	,	,	PUNCT
aji-171	562	28	&	&	CCONJ
aji-171	562	29	pizzagalli	pizzagalli	PROPN
aji-171	562	30	,	,	PUNCT
aji-171	562	31	d.	d.	PROPN
aji-171	562	32	a.	a.	PROPN
aji-171	562	33	(	(	PUNCT
aji-171	562	34	2024	2024	NUM
aji-171	562	35	)	)	PUNCT
aji-171	562	36	.	.	PUNCT
aji-171	563	1	individualized	individualized	ADJ
aji-171	563	2	functional	functional	ADJ
aji-171	563	3	brain	brain	NOUN
aji-171	563	4	system	system	NOUN
aji-171	563	5	topologies	topology	NOUN
aji-171	563	6	and	and	CCONJ
aji-171	563	7	major	major	ADJ
aji-171	563	8	depression	depression	NOUN
aji-171	563	9	:	:	PUNCT
aji-171	563	10	relationships	relationship	NOUN
aji-171	563	11	among	among	ADP
aji-171	563	12	patch	patch	ADJ
aji-171	563	13	sizes	size	NOUN
aji-171	563	14	and	and	CCONJ
aji-171	563	15	clinical	clinical	ADJ
aji-171	563	16	profiles	profile	NOUN
aji-171	563	17	and	and	CCONJ
aji-171	563	18	behavior	behavior	NOUN
aji-171	563	19	.	.	PUNCT
aji-171	564	1	biological	biological	ADJ
aji-171	564	2	psychiatry	psychiatry	NOUN
aji-171	564	3	cognitive	cognitive	ADJ
aji-171	564	4	neurosciences	neuroscience	NOUN
aji-171	564	5	and	and	CCONJ
aji-171	564	6	neuroimaging	neuroimaging	NOUN
aji-171	564	7	,	,	PUNCT
aji-171	564	8	9	9	NUM
aji-171	564	9	,	,	PUNCT
aji-171	564	10	616–625	616–625	NUM
aji-171	564	11	.	.	PUNCT
aji-171	565	1	schiliro	schiliro	PROPN
aji-171	565	2	,	,	PUNCT
aji-171	565	3	c.	c.	PROPN
aji-171	565	4	,	,	PUNCT
aji-171	565	5	&	&	CCONJ
aji-171	565	6	firestein	firestein	PROPN
aji-171	565	7	,	,	PUNCT
aji-171	565	8	b.	b.	PROPN
aji-171	565	9	l.	l.	PROPN
aji-171	565	10	(	(	PUNCT
aji-171	565	11	2021	2021	NUM
aji-171	565	12	)	)	PUNCT
aji-171	565	13	.	.	PUNCT
aji-171	566	1	mechanisms	mechanism	NOUN
aji-171	566	2	of	of	ADP
aji-171	566	3	metabolic	metabolic	NOUN
aji-171	566	4	reprogramming	reprogramme	VERB
aji-171	566	5	in	in	ADP
aji-171	566	6	cancer	cancer	NOUN
aji-171	566	7	cells	cell	NOUN
aji-171	566	8	supporting	support	VERB
aji-171	566	9	enhanced	enhanced	ADJ
aji-171	566	10	growth	growth	NOUN
aji-171	566	11	and	and	CCONJ
aji-171	566	12	proliferation	proliferation	NOUN
aji-171	566	13	.	.	PUNCT
aji-171	567	1	cells	cell	NOUN
aji-171	567	2	,	,	PUNCT
aji-171	567	3	10	10	NUM
aji-171	567	4	,	,	PUNCT
aji-171	567	5	1056	1056	NUM
aji-171	567	6	.	.	PUNCT
aji-171	568	1	sciacovelli	sciacovelli	PROPN
aji-171	568	2	,	,	PUNCT
aji-171	568	3	m.	m.	NOUN
aji-171	568	4	,	,	PUNCT
aji-171	568	5	&	&	CCONJ
aji-171	568	6	frezza	frezza	PROPN
aji-171	568	7	,	,	PUNCT
aji-171	568	8	c.	c.	PROPN
aji-171	568	9	(	(	PUNCT
aji-171	568	10	2016	2016	NUM
aji-171	568	11	)	)	PUNCT
aji-171	568	12	.	.	PUNCT
aji-171	569	1	oncometabolites	oncometabolite	NOUN
aji-171	569	2	:	:	PUNCT
aji-171	569	3	unconventional	unconventional	ADJ
aji-171	569	4	triggers	trigger	NOUN
aji-171	569	5	of	of	ADP
aji-171	569	6	oncogenic	oncogenic	ADJ
aji-171	569	7	signalling	signal	VERB
aji-171	569	8	cascades	cascade	NOUN
aji-171	569	9	.	.	PUNCT
aji-171	570	1	free	free	ADJ
aji-171	570	2	radical	radical	ADJ
aji-171	570	3	biology	biology	NOUN
aji-171	570	4	and	and	CCONJ
aji-171	570	5	medicine	medicine	NOUN
aji-171	570	6	,	,	PUNCT
aji-171	570	7	100	100	NUM
aji-171	570	8	,	,	PUNCT
aji-171	570	9	175	175	NUM
aji-171	570	10	–	–	PUNCT
aji-171	570	11	181	181	NUM
aji-171	570	12	.	.	PUNCT
aji-171	571	1	seifar	seifar	ADV
aji-171	571	2	,	,	PUNCT
aji-171	571	3	f.	f.	PROPN
aji-171	571	4	,	,	PUNCT
aji-171	571	5	dinasarapu	dinasarapu	PROPN
aji-171	571	6	,	,	PUNCT
aji-171	571	7	a.	a.	PROPN
aji-171	571	8	r.	r.	PROPN
aji-171	571	9	,	,	PUNCT
aji-171	571	10	&	&	CCONJ
aji-171	571	11	jinnah	jinnah	PROPN
aji-171	571	12	,	,	PUNCT
aji-171	571	13	h.	h.	PROPN
aji-171	571	14	(	(	PUNCT
aji-171	571	15	2022	2022	NUM
aji-171	571	16	)	)	PUNCT
aji-171	571	17	.	.	PUNCT
aji-171	572	1	uric	uric	ADJ
aji-171	572	2	acid	acid	NOUN
aji-171	572	3	in	in	ADP
aji-171	572	4	parkinson′s	parkinson′s	PROPN
aji-171	572	5	disease	disease	NOUN
aji-171	572	6	:	:	PUNCT
aji-171	572	7	what	what	PRON
aji-171	572	8	is	be	AUX
aji-171	572	9	the	the	DET
aji-171	572	10	connection	connection	NOUN
aji-171	572	11	?	?	PUNCT
aji-171	573	1	movement	movement	NOUN
aji-171	573	2	disorders	disorder	NOUN
aji-171	573	3	,	,	PUNCT
aji-171	573	4	37	37	NUM
aji-171	573	5	,	,	PUNCT
aji-171	573	6	2173–2183	2173–2183	NUM
aji-171	573	7	.	.	PUNCT
aji-171	574	1	silva	silva	PROPN
aji-171	574	2	,	,	PUNCT
aji-171	574	3	y.	y.	PROPN
aji-171	574	4	p.	p.	PROPN
aji-171	574	5	,	,	PUNCT
aji-171	574	6	bernardi	bernardi	PROPN
aji-171	574	7	,	,	PUNCT
aji-171	574	8	a.	a.	PROPN
aji-171	574	9	,	,	PUNCT
aji-171	574	10	&	&	CCONJ
aji-171	574	11	frozza	frozza	PROPN
aji-171	574	12	,	,	PUNCT
aji-171	574	13	r.	r.	PROPN
aji-171	574	14	l.	l.	PROPN
aji-171	574	15	(	(	PUNCT
aji-171	574	16	2020	2020	NUM
aji-171	574	17	)	)	PUNCT
aji-171	574	18	.	.	PUNCT
aji-171	575	1	the	the	DET
aji-171	575	2	role	role	NOUN
aji-171	575	3	of	of	ADP
aji-171	575	4	short	short	ADJ
aji-171	575	5	-	-	PUNCT
aji-171	575	6	chain	chain	NOUN
aji-171	575	7	fatty	fatty	NOUN
aji-171	575	8	acids	acid	NOUN
aji-171	575	9	from	from	ADP
aji-171	575	10	gut	gut	NOUN
aji-171	575	11	microbiota	microbiota	NOUN
aji-171	575	12	in	in	ADP
aji-171	575	13	gut	gut	NOUN
aji-171	575	14	-	-	PUNCT
aji-171	575	15	brain	brain	NOUN
aji-171	575	16	communication	communication	NOUN
aji-171	575	17	.	.	PUNCT
aji-171	576	1	frontiers	frontier	NOUN
aji-171	576	2	in	in	ADP
aji-171	576	3	endocrinology	endocrinology	NOUN
aji-171	576	4	,	,	PUNCT
aji-171	576	5	11	11	NUM
aji-171	576	6	,	,	PUNCT
aji-171	576	7	508738	508738	NUM
aji-171	576	8	.	.	PUNCT
aji-171	577	1	sun	sun	PROPN
aji-171	577	2	,	,	PUNCT
aji-171	577	3	h.	h.	PROPN
aji-171	577	4	,	,	PUNCT
aji-171	577	5	chen	chen	PROPN
aji-171	577	6	,	,	PUNCT
aji-171	577	7	s.	s.	PROPN
aji-171	577	8	,	,	PUNCT
aji-171	577	9	&	&	CCONJ
aji-171	577	10	liu	liu	PROPN
aji-171	577	11	,	,	PUNCT
aji-171	577	12	j.	j.	PROPN
aji-171	577	13	(	(	PUNCT
aji-171	577	14	2023	2023	NUM
aji-171	577	15	)	)	PUNCT
aji-171	577	16	.	.	PUNCT
aji-171	578	1	manganese	manganese	ADJ
aji-171	578	2	ions	ion	NOUN
aji-171	578	3	acts	act	VERB
aji-171	578	4	as	as	ADP
aji-171	578	5	a	a	DET
aji-171	578	6	messenger	messenger	NOUN
aji-171	578	7	to	to	PART
aji-171	578	8	regulate	regulate	VERB
aji-171	578	9	serum	serum	NOUN
aji-171	578	10	lipid	lipid	NOUN
aji-171	578	11	levels	level	NOUN
aji-171	578	12	.	.	PUNCT
aji-171	579	1	metabolism	metabolism	NOUN
aji-171	579	2	open	open	ADJ
aji-171	579	3	,	,	PUNCT
aji-171	579	4	100268	100268	NUM
aji-171	579	5	.	.	PUNCT
aji-171	580	1	https://doi.org/10.1016/j.metop.2023.10026	https://doi.org/10.1016/j.metop.2023.10026	PROPN
aji-171	580	2	8	8	NUM
aji-171	580	3	sun	sun	NOUN
aji-171	580	4	,	,	PUNCT
aji-171	580	5	h.	h.	PROPN
aji-171	580	6	,	,	PUNCT
aji-171	580	7	zhang	zhang	PROPN
aji-171	580	8	,	,	PUNCT
aji-171	580	9	a.	a.	PROPN
aji-171	580	10	h.	h.	PROPN
aji-171	580	11	,	,	PUNCT
aji-171	580	12	yang	yang	PROPN
aji-171	580	13	,	,	PUNCT
aji-171	580	14	l.	l.	PROPN
aji-171	580	15	,	,	PUNCT
aji-171	580	16	li	li	PROPN
aji-171	580	17	,	,	PUNCT
aji-171	580	18	m.	m.	NOUN
aji-171	580	19	x.	x.	PROPN
aji-171	580	20	,	,	PUNCT
aji-171	580	21	fang	fang	PROPN
aji-171	580	22	,	,	PUNCT
aji-171	580	23	h.	h.	PROPN
aji-171	580	24	,	,	PUNCT
aji-171	580	25	&	&	CCONJ
aji-171	580	26	xie	xie	PROPN
aji-171	580	27	,	,	PUNCT
aji-171	580	28	j.	j.	PROPN
aji-171	580	29	(	(	PUNCT
aji-171	580	30	2019	2019	NUM
aji-171	580	31	)	)	PUNCT
aji-171	580	32	.	.	PUNCT
aji-171	581	1	high	high	ADJ
aji-171	581	2	-	-	PUNCT
aji-171	581	3	throughput	throughput	NOUN
aji-171	581	4	chinmedomics	chinmedomic	NOUN
aji-171	581	5	strategy	strategy	NOUN
aji-171	581	6	for	for	ADP
aji-171	581	7	discovering	discover	VERB
aji-171	581	8	the	the	DET
aji-171	581	9	quality	quality	NOUN
aji-171	581	10	-	-	PUNCT
aji-171	581	11	markers	marker	NOUN
aji-171	581	12	and	and	CCONJ
aji-171	581	13	potential	potential	ADJ
aji-171	581	14	targets	target	NOUN
aji-171	581	15	for	for	ADP
aji-171	581	16	yinchenhao	yinchenhao	PROPN
aji-171	581	17	decoction	decoction	PROPN
aji-171	581	18	.	.	PUNCT
aji-171	582	1	phytomedicine	phytomedicine	PROPN
aji-171	582	2	,	,	PUNCT
aji-171	582	3	15(54	15(54	NOUN
aji-171	582	4	)	)	PUNCT
aji-171	582	5	,	,	PUNCT
aji-171	582	6	328–338	328–338	NUM
aji-171	582	7	.	.	PUNCT
aji-171	583	1	sun	sun	PROPN
aji-171	583	2	,	,	PUNCT
aji-171	583	3	h.	h.	PROPN
aji-171	583	4	,	,	PUNCT
aji-171	583	5	zhang	zhang	PROPN
aji-171	583	6	,	,	PUNCT
aji-171	583	7	a.	a.	PROPN
aji-171	583	8	h.	h.	PROPN
aji-171	583	9	,	,	PUNCT
aji-171	583	10	yang	yang	PROPN
aji-171	583	11	,	,	PUNCT
aji-171	583	12	l.	l.	PROPN
aji-171	583	13	,	,	PUNCT
aji-171	583	14	li	li	PROPN
aji-171	583	15	,	,	PUNCT
aji-171	583	16	m.	m.	NOUN
aji-171	583	17	x.	x.	PROPN
aji-171	583	18	,	,	PUNCT
aji-171	583	19	fang	fang	PROPN
aji-171	583	20	,	,	PUNCT
aji-171	583	21	h.	h.	PROPN
aji-171	583	22	,	,	PUNCT
aji-171	583	23	&	&	CCONJ
aji-171	583	24	xie	xie	PROPN
aji-171	583	25	,	,	PUNCT
aji-171	583	26	j.	j.	PROPN
aji-171	583	27	(	(	PUNCT
aji-171	583	28	2021	2021	NUM
aji-171	583	29	)	)	PUNCT
aji-171	583	30	.	.	PUNCT
aji-171	584	1	high	high	ADJ
aji-171	584	2	-	-	PUNCT
aji-171	584	3	throughput	throughput	NOUN
aji-171	584	4	chinmedomics	chinmedomic	NOUN
aji-171	584	5	strategy	strategy	NOUN
aji-171	584	6	for	for	ADP
aji-171	584	7	discovering	discover	VERB
aji-171	584	8	the	the	DET
aji-171	584	9	quality	quality	NOUN
aji-171	584	10	-	-	PUNCT
aji-171	584	11	markers	marker	NOUN
aji-171	584	12	and	and	CCONJ
aji-171	584	13	potential	potential	ADJ
aji-171	584	14	targets	target	NOUN
aji-171	584	15	for	for	ADP
aji-171	584	16	yinchenhao	yinchenhao	PROPN
aji-171	584	17	decoction	decoction	PROPN
aji-171	584	18	.	.	PUNCT
aji-171	585	1	phytomedicine	phytomedicine	PROPN
aji-171	585	2	,	,	PUNCT
aji-171	585	3	15(54	15(54	NOUN
aji-171	585	4	)	)	PUNCT
aji-171	585	5	,	,	PUNCT
aji-171	585	6	328–338	328–338	NUM
aji-171	585	7	.	.	PUNCT
aji-171	586	1	sun	sun	PROPN
aji-171	586	2	,	,	PUNCT
aji-171	586	3	j.	j.	PROPN
aji-171	586	4	,	,	PUNCT
aji-171	586	5	dong	dong	PROPN
aji-171	586	6	,	,	PUNCT
aji-171	586	7	q.	q.	PROPN
aji-171	586	8	x.	x.	PROPN
aji-171	586	9	,	,	PUNCT
aji-171	586	10	wang	wang	PROPN
aji-171	586	11	,	,	PUNCT
aji-171	586	12	s.	s.	PROPN
aji-171	586	13	w.	w.	PROPN
aji-171	586	14	,	,	PUNCT
aji-171	586	15	zheng	zheng	PROPN
aji-171	586	16	,	,	PUNCT
aji-171	586	17	y.	y.	PROPN
aji-171	586	18	b.	b.	PROPN
aji-171	586	19	,	,	PUNCT
aji-171	586	20	liu	liu	PROPN
aji-171	586	21	,	,	PUNCT
aji-171	586	22	x.	x.	PROPN
aji-171	586	23	x.	x.	PROPN
aji-171	586	24	,	,	PUNCT
aji-171	586	25	lu	lu	PROPN
aji-171	586	26	,	,	PUNCT
aji-171	586	27	t.	t.	PROPN
aji-171	586	28	s.	s.	PROPN
aji-171	586	29	,	,	PUNCT
aji-171	586	30	yuan	yuan	PROPN
aji-171	586	31	,	,	PUNCT
aji-171	586	32	k.	k.	PROPN
aji-171	586	33	,	,	PUNCT
aji-171	586	34	shi	shi	PROPN
aji-171	586	35	,	,	PUNCT
aji-171	586	36	j.	j.	PROPN
aji-171	586	37	,	,	PUNCT
aji-171	586	38	hu	hu	PROPN
aji-171	586	39	,	,	PUNCT
aji-171	586	40	b.	b.	PROPN
aji-171	586	41	,	,	PUNCT
aji-171	586	42	&	&	CCONJ
aji-171	586	43	lu	lu	PROPN
aji-171	586	44	,	,	PUNCT
aji-171	586	45	l.	l.	PROPN
aji-171	586	46	(	(	PUNCT
aji-171	586	47	2023	2023	NUM
aji-171	586	48	)	)	PUNCT
aji-171	586	49	.	.	PUNCT
aji-171	587	1	artificial	artificial	ADJ
aji-171	587	2	intelligence	intelligence	NOUN
aji-171	587	3	in	in	ADP
aji-171	587	4	psychiatry	psychiatry	NOUN
aji-171	587	5	research	research	NOUN
aji-171	587	6	,	,	PUNCT
aji-171	587	7	diagnosis	diagnosis	NOUN
aji-171	587	8	,	,	PUNCT
aji-171	587	9	and	and	CCONJ
aji-171	587	10	therapy	therapy	NOUN
aji-171	587	11	.	.	PUNCT
aji-171	588	1	asian	asian	ADJ
aji-171	588	2	journal	journal	PROPN
aji-171	588	3	of	of	ADP
aji-171	588	4	psychiatry	psychiatry	NOUN
aji-171	588	5	,	,	PUNCT
aji-171	588	6	87	87	NUM
aji-171	588	7	,	,	PUNCT
aji-171	588	8	103705	103705	NUM
aji-171	588	9	.	.	PUNCT
aji-171	589	1	surendran	surendran	NOUN
aji-171	589	2	,	,	PUNCT
aji-171	589	3	p.	p.	PROPN
aji-171	589	4	,	,	PUNCT
aji-171	589	5	stewart	stewart	PROPN
aji-171	589	6	,	,	PUNCT
aji-171	589	7	i.	i.	PROPN
aji-171	589	8	d.	d.	PROPN
aji-171	589	9	,	,	PUNCT
aji-171	589	10	au	au	PROPN
aji-171	589	11	yeung	yeung	PROPN
aji-171	589	12	,	,	PUNCT
aji-171	589	13	v.	v.	PROPN
aji-171	589	14	p.	p.	PROPN
aji-171	589	15	w.	w.	PROPN
aji-171	589	16	,	,	PUNCT
aji-171	589	17	pietzner	pietzner	NOUN
aji-171	589	18	,	,	PUNCT
aji-171	589	19	m.	m.	NOUN
aji-171	589	20	,	,	PUNCT
aji-171	589	21	raffler	raffler	NOUN
aji-171	589	22	,	,	PUNCT
aji-171	589	23	j.	j.	PROPN
aji-171	589	24	w.	w.	PROPN
aji-171	589	25	,	,	PUNCT
aji-171	589	26	&	&	CCONJ
aji-171	589	27	örheide	örheide	ADV
aji-171	589	28	,	,	PUNCT
aji-171	589	29	m.	m.	NOUN
aji-171	589	30	a.	a.	NOUN
aji-171	589	31	(	(	PUNCT
aji-171	589	32	2022	2022	NUM
aji-171	589	33	)	)	PUNCT
aji-171	589	34	.	.	PUNCT
aji-171	590	1	rare	rare	ADJ
aji-171	590	2	and	and	CCONJ
aji-171	590	3	common	common	ADJ
aji-171	590	4	genetic	genetic	ADJ
aji-171	590	5	determinants	determinant	NOUN
aji-171	590	6	of	of	ADP
aji-171	590	7	metabolic	metabolic	NOUN
aji-171	590	8	individuality	individuality	NOUN
aji-171	590	9	and	and	CCONJ
aji-171	590	10	mamman	mamman	NOUN
aji-171	590	11	et	et	PROPN
aji-171	590	12	al	al	PROPN
aji-171	590	13	.	.	PROPN
aji-171	590	14	;	;	PUNCT
aji-171	590	15	asian	asian	PROPN
aji-171	590	16	j.	j.	PROPN
aji-171	590	17	immunol	immunol	PROPN
aji-171	590	18	.	.	PROPN
aji-171	590	19	,	,	PUNCT
aji-171	590	20	vol	vol	NOUN
aji-171	590	21	.	.	PROPN
aji-171	590	22	8	8	NUM
aji-171	590	23	,	,	PUNCT
aji-171	590	24	no	no	INTJ
aji-171	590	25	.	.	NOUN
aji-171	590	26	1	1	NUM
aji-171	590	27	,	,	PUNCT
aji-171	590	28	pp	pp	ADJ
aji-171	590	29	.	.	PUNCT
aji-171	591	1	190	190	NUM
aji-171	591	2	-	-	SYM
aji-171	591	3	206	206	NUM
aji-171	591	4	,	,	PUNCT
aji-171	591	5	2025	2025	NUM
aji-171	591	6	;	;	PUNCT
aji-171	591	7	article	article	NOUN
aji-171	591	8	no.aji.140476	no.aji.140476	PART
aji-171	591	9	205	205	NUM
aji-171	591	10	their	their	PRON
aji-171	591	11	effects	effect	NOUN
aji-171	591	12	on	on	ADP
aji-171	591	13	human	human	ADJ
aji-171	591	14	health	health	NOUN
aji-171	591	15	.	.	PUNCT
aji-171	592	1	nature	nature	NOUN
aji-171	592	2	medicine	medicine	NOUN
aji-171	592	3	,	,	PUNCT
aji-171	592	4	28	28	NUM
aji-171	592	5	,	,	PUNCT
aji-171	592	6	2321–2332	2321–2332	NUM
aji-171	592	7	.	.	PUNCT
aji-171	593	1	török	török	PROPN
aji-171	593	2	,	,	PUNCT
aji-171	593	3	n.	n.	NOUN
aji-171	593	4	,	,	PUNCT
aji-171	593	5	tanaka	tanaka	PROPN
aji-171	593	6	,	,	PUNCT
aji-171	593	7	m.	m.	NOUN
aji-171	593	8	,	,	PUNCT
aji-171	593	9	&	&	CCONJ
aji-171	593	10	vécsei	vécsei	PROPN
aji-171	593	11	,	,	PUNCT
aji-171	593	12	l.	l.	PROPN
aji-171	593	13	(	(	PUNCT
aji-171	593	14	2020	2020	NUM
aji-171	593	15	)	)	PUNCT
aji-171	593	16	.	.	PUNCT
aji-171	594	1	searching	search	VERB
aji-171	594	2	for	for	ADP
aji-171	594	3	peripheral	peripheral	ADJ
aji-171	594	4	biomarkers	biomarker	NOUN
aji-171	594	5	in	in	ADP
aji-171	594	6	neurodegenerative	neurodegenerative	ADJ
aji-171	594	7	diseases	disease	NOUN
aji-171	594	8	:	:	PUNCT
aji-171	594	9	the	the	DET
aji-171	594	10	tryptophan	tryptophan	NOUN
aji-171	594	11	-	-	PUNCT
aji-171	594	12	kynurenine	kynurenine	NOUN
aji-171	594	13	metabolic	metabolic	NOUN
aji-171	594	14	pathway	pathway	NOUN
aji-171	594	15	.	.	PUNCT
aji-171	595	1	international	international	ADJ
aji-171	595	2	journal	journal	NOUN
aji-171	595	3	of	of	ADP
aji-171	595	4	molecular	molecular	ADJ
aji-171	595	5	sciences	science	NOUN
aji-171	595	6	,	,	PUNCT
aji-171	595	7	21	21	NUM
aji-171	595	8	,	,	PUNCT
aji-171	595	9	9338	9338	NUM
aji-171	595	10	.	.	PUNCT
aji-171	596	1	trpkov	trpkov	NOUN
aji-171	596	2	,	,	PUNCT
aji-171	596	3	k.	k.	PROPN
aji-171	596	4	,	,	PUNCT
aji-171	596	5	he	he	PRON
aji-171	596	6	s	s	VERB
aji-171	596	7	,	,	PUNCT
aji-171	596	8	o.	o.	PROPN
aji-171	596	9	,	,	PUNCT
aji-171	596	10	agaimy	agaimy	PROPN
aji-171	596	11	,	,	PUNCT
aji-171	596	12	a.	a.	NOUN
aji-171	596	13	,	,	PUNCT
aji-171	596	14	bonert	bonert	PROPN
aji-171	596	15	,	,	PUNCT
aji-171	596	16	m.	m.	NOUN
aji-171	596	17	,	,	PUNCT
aji-171	596	18	martinek	martinek	ADJ
aji-171	596	19	,	,	PUNCT
aji-171	596	20	p.	p.	NOUN
aji-171	596	21	,	,	PUNCT
aji-171	596	22	magi	magi	NOUN
aji-171	596	23	-	-	PUNCT
aji-171	596	24	galluzzi	galluzzi	NOUN
aji-171	596	25	,	,	PUNCT
aji-171	596	26	c.	c.	NOUN
aji-171	596	27	,	,	PUNCT
aji-171	596	28	kristiansen	kristiansen	PROPN
aji-171	596	29	,	,	PUNCT
aji-171	596	30	g.	g.	PROPN
aji-171	596	31	,	,	PUNCT
aji-171	596	32	lüders	lüder	NOUN
aji-171	596	33	,	,	PUNCT
aji-171	596	34	c.	c.	PROPN
aji-171	596	35	,	,	PUNCT
aji-171	596	36	nesi	nesi	PROPN
aji-171	596	37	,	,	PUNCT
aji-171	596	38	g.	g.	PROPN
aji-171	596	39	,	,	PUNCT
aji-171	596	40	&	&	CCONJ
aji-171	596	41	compérat	compérat	PROPN
aji-171	596	42	,	,	PUNCT
aji-171	596	43	e.	e.	PROPN
aji-171	596	44	(	(	PUNCT
aji-171	596	45	2016	2016	NUM
aji-171	596	46	)	)	PUNCT
aji-171	596	47	.	.	PUNCT
aji-171	597	1	fumarate	fumarate	ADJ
aji-171	597	2	hydratase	hydratase	ADJ
aji-171	597	3	–	–	PUNCT
aji-171	597	4	deficient	deficient	ADJ
aji-171	597	5	renal	renal	ADJ
aji-171	597	6	cell	cell	NOUN
aji-171	597	7	carcinoma	carcinoma	NOUN
aji-171	597	8	is	be	AUX
aji-171	597	9	strongly	strongly	ADV
aji-171	597	10	correlated	correlate	VERB
aji-171	597	11	with	with	ADP
aji-171	597	12	fumarate	fumarate	ADJ
aji-171	597	13	hydratase	hydratase	ADJ
aji-171	597	14	mutation	mutation	NOUN
aji-171	597	15	and	and	CCONJ
aji-171	597	16	hereditary	hereditary	ADJ
aji-171	597	17	leiomyomatosis	leiomyomatosis	NOUN
aji-171	597	18	and	and	CCONJ
aji-171	597	19	renal	renal	ADJ
aji-171	597	20	cell	cell	NOUN
aji-171	597	21	carcinoma	carcinoma	NOUN
aji-171	597	22	syndrome	syndrome	NOUN
aji-171	597	23	.	.	PUNCT
aji-171	598	1	american	american	ADJ
aji-171	598	2	journal	journal	PROPN
aji-171	598	3	of	of	ADP
aji-171	598	4	surgical	surgical	ADJ
aji-171	598	5	pathology	pathology	NOUN
aji-171	598	6	,	,	PUNCT
aji-171	598	7	40	40	NUM
aji-171	598	8	,	,	PUNCT
aji-171	598	9	865–875	865–875	NUM
aji-171	598	10	.	.	PUNCT
aji-171	599	1	upadhyay	upadhyay	PROPN
aji-171	599	2	,	,	PUNCT
aji-171	599	3	r.	r.	PROPN
aji-171	599	4	k.	k.	PROPN
aji-171	599	5	(	(	PUNCT
aji-171	599	6	2015	2015	NUM
aji-171	599	7	)	)	PUNCT
aji-171	599	8	.	.	PUNCT
aji-171	600	1	emerging	emerge	VERB
aji-171	600	2	risk	risk	NOUN
aji-171	600	3	biomarkers	biomarker	NOUN
aji-171	600	4	in	in	ADP
aji-171	600	5	cardiovascular	cardiovascular	ADJ
aji-171	600	6	diseases	disease	NOUN
aji-171	600	7	and	and	CCONJ
aji-171	600	8	disorders	disorder	NOUN
aji-171	600	9	.	.	PUNCT
aji-171	601	1	journal	journal	NOUN
aji-171	601	2	of	of	ADP
aji-171	601	3	lipids	lipid	NOUN
aji-171	601	4	,	,	PUNCT
aji-171	601	5	971453	971453	NUM
aji-171	601	6	.	.	PUNCT
aji-171	602	1	vanweert	vanweert	PROPN
aji-171	602	2	,	,	PUNCT
aji-171	602	3	f.	f.	PROPN
aji-171	602	4	,	,	PUNCT
aji-171	602	5	schrauwen	schrauwen	NOUN
aji-171	602	6	,	,	PUNCT
aji-171	602	7	p.	p.	NOUN
aji-171	602	8	,	,	PUNCT
aji-171	602	9	&	&	CCONJ
aji-171	602	10	phielix	phielix	PROPN
aji-171	602	11	,	,	PUNCT
aji-171	602	12	e.	e.	PROPN
aji-171	602	13	(	(	PUNCT
aji-171	602	14	2022	2022	NUM
aji-171	602	15	)	)	PUNCT
aji-171	602	16	.	.	PUNCT
aji-171	603	1	role	role	NOUN
aji-171	603	2	of	of	ADP
aji-171	603	3	branched	branch	VERB
aji-171	603	4	-	-	PUNCT
aji-171	603	5	chain	chain	NOUN
aji-171	603	6	amino	amino	NOUN
aji-171	603	7	acid	acid	NOUN
aji-171	603	8	metabolism	metabolism	NOUN
aji-171	603	9	in	in	ADP
aji-171	603	10	the	the	DET
aji-171	603	11	pathogenesis	pathogenesis	NOUN
aji-171	603	12	of	of	ADP
aji-171	603	13	obesity	obesity	NOUN
aji-171	603	14	and	and	CCONJ
aji-171	603	15	type	type	NOUN
aji-171	603	16	2	2	NUM
aji-171	603	17	diabetes	diabetes	NOUN
aji-171	603	18	-	-	PUNCT
aji-171	603	19	related	relate	VERB
aji-171	603	20	metabolic	metabolic	NOUN
aji-171	603	21	disturbances	disturbance	NOUN
aji-171	603	22	bcaa	bcaa	NOUN
aji-171	603	23	metabolism	metabolism	NOUN
aji-171	603	24	in	in	ADP
aji-171	603	25	type	type	NOUN
aji-171	603	26	2	2	NUM
aji-171	603	27	diabetes	diabetes	NOUN
aji-171	603	28	.	.	PUNCT
aji-171	604	1	nutrition	nutrition	NOUN
aji-171	604	2	and	and	CCONJ
aji-171	604	3	diabetes	diabetes	NOUN
aji-171	604	4	,	,	PUNCT
aji-171	604	5	12	12	NUM
aji-171	604	6	,	,	PUNCT
aji-171	604	7	35	35	NUM
aji-171	604	8	.	.	PUNCT
aji-171	604	9	vargas	vargas	PROPN
aji-171	604	10	,	,	PUNCT
aji-171	604	11	a.	a.	PROPN
aji-171	604	12	j.	j.	PROPN
aji-171	604	13	,	,	PUNCT
aji-171	604	14	&	&	CCONJ
aji-171	604	15	harris	harris	PROPN
aji-171	604	16	,	,	PUNCT
aji-171	604	17	c.	c.	PROPN
aji-171	604	18	c.	c.	PROPN
aji-171	604	19	(	(	PUNCT
aji-171	604	20	2017	2017	NUM
aji-171	604	21	)	)	PUNCT
aji-171	604	22	.	.	PUNCT
aji-171	605	1	biomarker	biomarker	NOUN
aji-171	605	2	development	development	NOUN
aji-171	605	3	in	in	ADP
aji-171	605	4	the	the	DET
aji-171	605	5	precision	precision	NOUN
aji-171	605	6	medicine	medicine	NOUN
aji-171	605	7	era	era	NOUN
aji-171	605	8	:	:	PUNCT
aji-171	605	9	lung	lung	NOUN
aji-171	605	10	cancer	cancer	NOUN
aji-171	605	11	as	as	ADP
aji-171	605	12	a	a	DET
aji-171	605	13	case	case	NOUN
aji-171	605	14	study	study	NOUN
aji-171	605	15	.	.	PUNCT
aji-171	606	1	nature	nature	NOUN
aji-171	606	2	reviews	review	VERB
aji-171	606	3	cancer	cancer	NOUN
aji-171	606	4	,	,	PUNCT
aji-171	606	5	16	16	NUM
aji-171	606	6	,	,	PUNCT
aji-171	606	7	525–537	525–537	NUM
aji-171	606	8	.	.	PUNCT
aji-171	607	1	vo	vo	PROPN
aji-171	607	2	,	,	PUNCT
aji-171	607	3	d.	d.	PROPN
aji-171	607	4	k.	k.	PROPN
aji-171	607	5	,	,	PUNCT
aji-171	607	6	&	&	CCONJ
aji-171	607	7	trinh	trinh	PROPN
aji-171	607	8	,	,	PUNCT
aji-171	607	9	k.	k.	PROPN
aji-171	607	10	t.	t.	PROPN
aji-171	607	11	l.	l.	PROPN
aji-171	607	12	(	(	PUNCT
aji-171	607	13	2024	2024	NUM
aji-171	607	14	)	)	PUNCT
aji-171	607	15	.	.	PUNCT
aji-171	608	1	emerging	emerge	VERB
aji-171	608	2	biomarkers	biomarker	NOUN
aji-171	608	3	in	in	ADP
aji-171	608	4	metabolomics	metabolomic	NOUN
aji-171	608	5	:	:	PUNCT
aji-171	608	6	advancements	advancement	NOUN
aji-171	608	7	in	in	ADP
aji-171	608	8	precision	precision	NOUN
aji-171	608	9	health	health	NOUN
aji-171	608	10	and	and	CCONJ
aji-171	608	11	disease	disease	NOUN
aji-171	608	12	diagnosis	diagnosis	NOUN
aji-171	608	13	.	.	PUNCT
aji-171	609	1	international	international	ADJ
aji-171	609	2	journal	journal	NOUN
aji-171	609	3	of	of	ADP
aji-171	609	4	molecular	molecular	ADJ
aji-171	609	5	sciences	science	NOUN
aji-171	609	6	,	,	PUNCT
aji-171	609	7	25	25	NUM
aji-171	609	8	,	,	PUNCT
aji-171	609	9	13190	13190	NUM
aji-171	609	10	.	.	PUNCT
aji-171	610	1	voevodskaya	voevodskaya	PROPN
aji-171	610	2	,	,	PUNCT
aji-171	610	3	o.	o.	PROPN
aji-171	610	4	,	,	PUNCT
aji-171	610	5	sundgren	sundgren	PROPN
aji-171	610	6	,	,	PUNCT
aji-171	610	7	p.	p.	PROPN
aji-171	610	8	c.	c.	PROPN
aji-171	610	9	,	,	PUNCT
aji-171	610	10	strandberg	strandberg	PROPN
aji-171	610	11	,	,	PUNCT
aji-171	610	12	o.	o.	PROPN
aji-171	610	13	,	,	PUNCT
aji-171	610	14	zetterberg	zetterberg	PROPN
aji-171	610	15	,	,	PUNCT
aji-171	610	16	h.	h.	PROPN
aji-171	610	17	,	,	PUNCT
aji-171	610	18	minthon	minthon	PROPN
aji-171	610	19	,	,	PUNCT
aji-171	610	20	l.	l.	PROPN
aji-171	610	21	,	,	PUNCT
aji-171	610	22	blennow	blennow	ADV
aji-171	610	23	,	,	PUNCT
aji-171	610	24	k.	k.	PROPN
aji-171	610	25	,	,	PUNCT
aji-171	610	26	wahlund	wahlund	PROPN
aji-171	610	27	,	,	PUNCT
aji-171	610	28	l.	l.	PROPN
aji-171	610	29	o.	o.	PROPN
aji-171	610	30	,	,	PUNCT
aji-171	610	31	westman	westman	NOUN
aji-171	610	32	,	,	PUNCT
aji-171	610	33	e.	e.	PROPN
aji-171	610	34	,	,	PUNCT
aji-171	610	35	&	&	CCONJ
aji-171	610	36	hansson	hansson	PROPN
aji-171	610	37	,	,	PUNCT
aji-171	610	38	o.	o.	PROPN
aji-171	610	39	(	(	PUNCT
aji-171	610	40	2016	2016	NUM
aji-171	610	41	)	)	PUNCT
aji-171	610	42	.	.	PUNCT
aji-171	611	1	swedish	swedish	PROPN
aji-171	611	2	biofinder	biofinder	PROPN
aji-171	611	3	study	study	PROPN
aji-171	611	4	group	group	NOUN
aji-171	611	5	.	.	PUNCT
aji-171	612	1	myo	myo	NOUN
aji-171	612	2	-	-	PUNCT
aji-171	612	3	inositol	inositol	NOUN
aji-171	612	4	changes	change	NOUN
aji-171	612	5	precede	precede	VERB
aji-171	612	6	amyloid	amyloid	NOUN
aji-171	612	7	pathology	pathology	NOUN
aji-171	612	8	and	and	CCONJ
aji-171	612	9	relate	relate	VERB
aji-171	612	10	to	to	ADP
aji-171	612	11	apoe	apoe	ADJ
aji-171	612	12	genotype	genotype	NOUN
aji-171	612	13	in	in	ADP
aji-171	612	14	alzheimer	alzheimer	PROPN
aji-171	612	15	disease	disease	PROPN
aji-171	612	16	.	.	PUNCT
aji-171	613	1	neurology	neurology	NOUN
aji-171	613	2	,	,	PUNCT
aji-171	613	3	86	86	NUM
aji-171	613	4	,	,	PUNCT
aji-171	613	5	1754–1761	1754–1761	NUM
aji-171	613	6	.	.	PUNCT
aji-171	614	1	vona	vona	PROPN
aji-171	614	2	,	,	PUNCT
aji-171	614	3	r.	r.	PROPN
aji-171	614	4	,	,	PUNCT
aji-171	614	5	gambardella	gambardella	PROPN
aji-171	614	6	,	,	PUNCT
aji-171	614	7	l.	l.	PROPN
aji-171	614	8	,	,	PUNCT
aji-171	614	9	cittadini	cittadini	PROPN
aji-171	614	10	,	,	PUNCT
aji-171	614	11	c.	c.	NOUN
aji-171	614	12	,	,	PUNCT
aji-171	614	13	straface	straface	NOUN
aji-171	614	14	,	,	PUNCT
aji-171	614	15	e.	e.	PROPN
aji-171	614	16	,	,	PUNCT
aji-171	614	17	&	&	CCONJ
aji-171	614	18	pietraforte	pietraforte	PROPN
aji-171	614	19	,	,	PUNCT
aji-171	614	20	d.	d.	PROPN
aji-171	614	21	(	(	PUNCT
aji-171	614	22	2019	2019	NUM
aji-171	614	23	)	)	PUNCT
aji-171	614	24	.	.	PUNCT
aji-171	615	1	biomarkers	biomarker	NOUN
aji-171	615	2	of	of	ADP
aji-171	615	3	oxidative	oxidative	ADJ
aji-171	615	4	stress	stress	NOUN
aji-171	615	5	in	in	ADP
aji-171	615	6	metabolic	metabolic	NOUN
aji-171	615	7	syndrome	syndrome	NOUN
aji-171	615	8	and	and	CCONJ
aji-171	615	9	associated	associated	ADJ
aji-171	615	10	diseases	disease	NOUN
aji-171	615	11	.	.	PUNCT
aji-171	616	1	oxidative	oxidative	ADJ
aji-171	616	2	medicine	medicine	NOUN
aji-171	616	3	and	and	CCONJ
aji-171	616	4	cellular	cellular	ADJ
aji-171	616	5	longevity	longevity	NOUN
aji-171	616	6	,	,	PUNCT
aji-171	616	7	8267234	8267234	NUM
aji-171	616	8	.	.	PUNCT
aji-171	617	1	wada	wada	PROPN
aji-171	617	2	,	,	PUNCT
aji-171	617	3	m.	m.	NOUN
aji-171	617	4	,	,	PUNCT
aji-171	617	5	noda	noda	PROPN
aji-171	617	6	,	,	PUNCT
aji-171	617	7	y.	y.	PROPN
aji-171	617	8	,	,	PUNCT
aji-171	617	9	iwata	iwata	NOUN
aji-171	617	10	,	,	PUNCT
aji-171	617	11	y.	y.	PROPN
aji-171	617	12	,	,	PUNCT
aji-171	617	13	tsugawa	tsugawa	PROPN
aji-171	617	14	,	,	PUNCT
aji-171	617	15	s.	s.	PROPN
aji-171	617	16	,	,	PUNCT
aji-171	617	17	yoshida	yoshida	PROPN
aji-171	617	18	,	,	PUNCT
aji-171	617	19	k.	k.	PROPN
aji-171	617	20	,	,	PUNCT
aji-171	617	21	tani	tani	PROPN
aji-171	617	22	,	,	PUNCT
aji-171	617	23	h.	h.	PROPN
aji-171	617	24	,	,	PUNCT
aji-171	617	25	hirano	hirano	PROPN
aji-171	617	26	,	,	PUNCT
aji-171	617	27	y.	y.	PROPN
aji-171	617	28	,	,	PUNCT
aji-171	617	29	koike	koike	PROPN
aji-171	617	30	,	,	PUNCT
aji-171	617	31	s.	s.	PROPN
aji-171	617	32	,	,	PUNCT
aji-171	617	33	sasabayashi	sasabayashi	PROPN
aji-171	617	34	,	,	PUNCT
aji-171	617	35	d.	d.	PROPN
aji-171	617	36	,	,	PUNCT
aji-171	617	37	&	&	CCONJ
aji-171	617	38	katayama	katayama	PROPN
aji-171	617	39	,	,	PUNCT
aji-171	617	40	h.	h.	PROPN
aji-171	617	41	(	(	PUNCT
aji-171	617	42	2022	2022	NUM
aji-171	617	43	)	)	PUNCT
aji-171	617	44	.	.	PUNCT
aji-171	618	1	dopaminergic	dopaminergic	ADJ
aji-171	618	2	dysfunction	dysfunction	NOUN
aji-171	618	3	and	and	CCONJ
aji-171	618	4	excitatory	excitatory	NOUN
aji-171	618	5	/	/	SYM
aji-171	618	6	inhibitory	inhibitory	ADJ
aji-171	618	7	imbalance	imbalance	NOUN
aji-171	618	8	in	in	ADP
aji-171	618	9	treatment	treatment	NOUN
aji-171	618	10	-	-	PUNCT
aji-171	618	11	resistant	resistant	ADJ
aji-171	618	12	schizophrenia	schizophrenia	NOUN
aji-171	618	13	and	and	CCONJ
aji-171	618	14	novel	novel	ADJ
aji-171	618	15	neuromodulatory	neuromodulatory	ADJ
aji-171	618	16	treatment	treatment	NOUN
aji-171	618	17	.	.	PUNCT
aji-171	619	1	molecular	molecular	ADJ
aji-171	619	2	psychiatry	psychiatry	NOUN
aji-171	619	3	,	,	PUNCT
aji-171	619	4	27	27	NUM
aji-171	619	5	,	,	PUNCT
aji-171	619	6	2950–2967	2950–2967	NUM
aji-171	619	7	.	.	PUNCT
aji-171	620	1	wang	wang	PROPN
aji-171	620	2	,	,	PUNCT
aji-171	620	3	j.	j.	PROPN
aji-171	620	4	h.	h.	PROPN
aji-171	620	5	,	,	PUNCT
aji-171	620	6	chen	chen	PROPN
aji-171	620	7	,	,	PUNCT
aji-171	620	8	w.	w.	PROPN
aji-171	620	9	l.	l.	PROPN
aji-171	620	10	,	,	PUNCT
aji-171	620	11	li	li	PROPN
aji-171	620	12	,	,	PUNCT
aji-171	620	13	j.	j.	PROPN
aji-171	620	14	m.	m.	PROPN
aji-171	620	15	,	,	PUNCT
aji-171	620	16	wu	wu	PROPN
aji-171	620	17	,	,	PUNCT
aji-171	620	18	s.	s.	PROPN
aji-171	620	19	f.	f.	PROPN
aji-171	620	20	,	,	PUNCT
aji-171	620	21	chen	chen	PROPN
aji-171	620	22	,	,	PUNCT
aji-171	620	23	t.	t.	PROPN
aji-171	620	24	l.	l.	PROPN
aji-171	620	25	,	,	PUNCT
aji-171	620	26	zhu	zhu	PROPN
aji-171	620	27	,	,	PUNCT
aji-171	620	28	y.	y.	PROPN
aji-171	620	29	m.	m.	PROPN
aji-171	620	30	,	,	PUNCT
aji-171	620	31	zhang	zhang	PROPN
aji-171	620	32	,	,	PUNCT
aji-171	620	33	w.	w.	PROPN
aji-171	620	34	n.	n.	PROPN
aji-171	620	35	,	,	PUNCT
aji-171	620	36	li	li	PROPN
aji-171	620	37	,	,	PUNCT
aji-171	620	38	y.	y.	PROPN
aji-171	620	39	,	,	PUNCT
aji-171	620	40	qiu	qiu	PROPN
aji-171	620	41	,	,	PUNCT
aji-171	620	42	y.	y.	PROPN
aji-171	620	43	p.	p.	PROPN
aji-171	620	44	,	,	PUNCT
aji-171	620	45	&	&	CCONJ
aji-171	620	46	zhao	zhao	PROPN
aji-171	620	47	,	,	PUNCT
aji-171	620	48	a.	a.	PROPN
aji-171	620	49	h.	h.	PROPN
aji-171	620	50	(	(	PUNCT
aji-171	620	51	2013	2013	NUM
aji-171	620	52	)	)	PUNCT
aji-171	620	53	.	.	PUNCT
aji-171	621	1	prognostic	prognostic	ADJ
aji-171	621	2	significance	significance	NOUN
aji-171	621	3	of	of	ADP
aji-171	621	4	2hydroxyglutarate	2hydroxyglutarate	NUM
aji-171	621	5	levels	level	NOUN
aji-171	621	6	in	in	ADP
aji-171	621	7	acute	acute	ADJ
aji-171	621	8	myeloid	myeloid	NOUN
aji-171	621	9	leukemia	leukemia	NOUN
aji-171	621	10	in	in	ADP
aji-171	621	11	china	china	PROPN
aji-171	621	12	.	.	PUNCT
aji-171	622	1	proceedings	proceeding	NOUN
aji-171	622	2	of	of	ADP
aji-171	622	3	the	the	DET
aji-171	622	4	national	national	PROPN
aji-171	622	5	academy	academy	PROPN
aji-171	622	6	of	of	ADP
aji-171	622	7	sciences	sciences	PROPN
aji-171	622	8	usa	usa	PROPN
aji-171	622	9	,	,	PUNCT
aji-171	622	10	110	110	NUM
aji-171	622	11	,	,	PUNCT
aji-171	622	12	17017–17022	17017–17022	NUM
aji-171	622	13	.	.	PUNCT
aji-171	623	1	wang	wang	PROPN
aji-171	623	2	,	,	PUNCT
aji-171	623	3	j.	j.	PROPN
aji-171	623	4	,	,	PUNCT
aji-171	623	5	he	he	PRON
aji-171	623	6	,	,	PUNCT
aji-171	623	7	y.	y.	PROPN
aji-171	623	8	,	,	PUNCT
aji-171	623	9	chen	chen	PROPN
aji-171	623	10	,	,	PUNCT
aji-171	623	11	x.	x.	PROPN
aji-171	623	12	,	,	PUNCT
aji-171	623	13	huang	huang	PROPN
aji-171	623	14	,	,	PUNCT
aji-171	623	15	l.	l.	PROPN
aji-171	623	16	,	,	PUNCT
aji-171	623	17	li	li	PROPN
aji-171	623	18	,	,	PUNCT
aji-171	623	19	j.	j.	PROPN
aji-171	623	20	,	,	PUNCT
aji-171	623	21	you	you	PRON
aji-171	623	22	,	,	PUNCT
aji-171	623	23	z.	z.	PROPN
aji-171	623	24	,	,	PUNCT
aji-171	623	25	huang	huang	PROPN
aji-171	623	26	,	,	PUNCT
aji-171	623	27	q.	q.	PROPN
aji-171	623	28	,	,	PUNCT
aji-171	623	29	ren	ren	PROPN
aji-171	623	30	,	,	PUNCT
aji-171	623	31	s.	s.	PROPN
aji-171	623	32	,	,	PUNCT
aji-171	623	33	he	he	PRON
aji-171	623	34	,	,	PUNCT
aji-171	623	35	k.	k.	PROPN
aji-171	623	36	,	,	PUNCT
aji-171	623	37	&	&	CCONJ
aji-171	623	38	schibli	schibli	PROPN
aji-171	623	39	,	,	PUNCT
aji-171	623	40	r.	r.	PROPN
aji-171	623	41	(	(	PUNCT
aji-171	623	42	2024	2024	NUM
aji-171	623	43	)	)	PUNCT
aji-171	623	44	.	.	PUNCT
aji-171	624	1	metabotropic	metabotropic	NOUN
aji-171	624	2	glutamate	glutamate	ADJ
aji-171	624	3	receptor	receptor	NOUN
aji-171	624	4	5	5	NUM
aji-171	624	5	(	(	PUNCT
aji-171	624	6	mglur5	mglur5	NOUN
aji-171	624	7	)	)	PUNCT
aji-171	624	8	is	be	AUX
aji-171	624	9	associated	associate	VERB
aji-171	624	10	with	with	ADP
aji-171	624	11	neurodegeneration	neurodegeneration	NOUN
aji-171	624	12	and	and	CCONJ
aji-171	624	13	amyloid	amyloid	NOUN
aji-171	624	14	deposition	deposition	NOUN
aji-171	624	15	in	in	ADP
aji-171	624	16	alzheimer	alzheimer	PROPN
aji-171	624	17	’s	’s	PART
aji-171	624	18	disease	disease	NOUN
aji-171	624	19	:	:	PUNCT
aji-171	624	20	a	a	DET
aji-171	624	21	[	[	X
aji-171	624	22	18f	18f	X
aji-171	624	23	]	]	X
aji-171	624	24	pss232	pss232	PROPN
aji-171	624	25	pet	pet	NOUN
aji-171	624	26	/	/	SYM
aji-171	624	27	mri	mri	NOUN
aji-171	624	28	study	study	NOUN
aji-171	624	29	.	.	PUNCT
aji-171	625	1	alzheimer	alzheimer	PROPN
aji-171	625	2	’s	’s	PART
aji-171	625	3	research	research	PROPN
aji-171	625	4	&	&	CCONJ
aji-171	625	5	therapy	therapy	NOUN
aji-171	625	6	,	,	PUNCT
aji-171	625	7	16	16	NUM
aji-171	625	8	,	,	PUNCT
aji-171	625	9	9	9	NUM
aji-171	625	10	.	.	X
aji-171	625	11	wang	wang	PROPN
aji-171	625	12	,	,	PUNCT
aji-171	625	13	l.	l.	PROPN
aji-171	625	14	,	,	PUNCT
aji-171	625	15	du	du	PROPN
aji-171	625	16	,	,	PUNCT
aji-171	625	17	r.	r.	PROPN
aji-171	625	18	,	,	PUNCT
aji-171	625	19	han	han	PROPN
aji-171	625	20	,	,	PUNCT
aji-171	625	21	l.	l.	PROPN
aji-171	625	22	,	,	PUNCT
aji-171	625	23	yang	yang	PROPN
aji-171	625	24	,	,	PUNCT
aji-171	625	25	r.	r.	PROPN
aji-171	625	26	,	,	PUNCT
aji-171	625	27	&	&	CCONJ
aji-171	625	28	li	li	PROPN
aji-171	625	29	,	,	PUNCT
aji-171	625	30	y.	y.	PROPN
aji-171	625	31	(	(	PUNCT
aji-171	625	32	2024	2024	NUM
aji-171	625	33	)	)	PUNCT
aji-171	625	34	.	.	PUNCT
aji-171	626	1	a	a	DET
aji-171	626	2	new	new	ADJ
aji-171	626	3	missense	missense	NOUN
aji-171	626	4	mutation	mutation	NOUN
aji-171	626	5	c.1240a	c.1240a	X
aji-171	626	6	>	>	X
aji-171	626	7	g	g	NOUN
aji-171	626	8	in	in	ADP
aji-171	626	9	fumarate	fumarate	ADJ
aji-171	626	10	hydratase	hydratase	ADJ
aji-171	626	11	gene	gene	NOUN
aji-171	626	12	leads	lead	VERB
aji-171	626	13	to	to	ADP
aji-171	626	14	uterine	uterine	ADJ
aji-171	626	15	leiomyoma	leiomyoma	NOUN
aji-171	626	16	associated	associate	VERB
aji-171	626	17	hereditary	hereditary	ADJ
aji-171	626	18	leiomyomatosis	leiomyomatosis	NOUN
aji-171	626	19	and	and	CCONJ
aji-171	626	20	renal	renal	ADJ
aji-171	626	21	cell	cell	NOUN
aji-171	626	22	cancer	cancer	NOUN
aji-171	626	23	(	(	PUNCT
aji-171	626	24	hlrcc	hlrcc	NOUN
aji-171	626	25	)	)	PUNCT
aji-171	626	26	syndrome	syndrome	NOUN
aji-171	626	27	in	in	ADP
aji-171	626	28	chinese	chinese	PROPN
aji-171	626	29	.	.	PUNCT
aji-171	627	1	translational	translational	ADJ
aji-171	627	2	oncology	oncology	NOUN
aji-171	627	3	,	,	PUNCT
aji-171	627	4	45	45	NUM
aji-171	627	5	,	,	PUNCT
aji-171	627	6	101963	101963	NUM
aji-171	627	7	.	.	PUNCT
aji-171	628	1	wang	wang	PROPN
aji-171	628	2	,	,	PUNCT
aji-171	628	3	x.	x.	PROPN
aji-171	628	4	,	,	PUNCT
aji-171	628	5	huang	huang	PROPN
aji-171	628	6	,	,	PUNCT
aji-171	628	7	r.	r.	PROPN
aji-171	628	8	,	,	PUNCT
aji-171	628	9	wang	wang	PROPN
aji-171	628	10	,	,	PUNCT
aji-171	628	11	y.	y.	PROPN
aji-171	628	12	,	,	PUNCT
aji-171	628	13	zhou	zhou	PROPN
aji-171	628	14	,	,	PUNCT
aji-171	628	15	w.	w.	PROPN
aji-171	628	16	,	,	PUNCT
aji-171	628	17	hu	hu	PROPN
aji-171	628	18	,	,	PUNCT
aji-171	628	19	y.	y.	PROPN
aji-171	628	20	,	,	PUNCT
aji-171	628	21	&	&	CCONJ
aji-171	628	22	yao	yao	PROPN
aji-171	628	23	,	,	PUNCT
aji-171	628	24	y.	y.	PROPN
aji-171	628	25	(	(	PUNCT
aji-171	628	26	2023	2023	NUM
aji-171	628	27	)	)	PUNCT
aji-171	628	28	.	.	PUNCT
aji-171	629	1	manganese	manganese	ADJ
aji-171	629	2	regulation	regulation	NOUN
aji-171	629	3	of	of	ADP
aji-171	629	4	copii	copii	PROPN
aji-171	629	5	condensation	condensation	NOUN
aji-171	629	6	controls	control	VERB
aji-171	629	7	circulating	circulate	VERB
aji-171	629	8	lipid	lipid	NOUN
aji-171	629	9	homeostasis	homeostasis	NOUN
aji-171	629	10	.	.	PUNCT
aji-171	630	1	nature	nature	NOUN
aji-171	630	2	cell	cell	NOUN
aji-171	630	3	biology	biology	NOUN
aji-171	630	4	,	,	PUNCT
aji-171	630	5	25	25	NUM
aji-171	630	6	,	,	PUNCT
aji-171	630	7	1650–1663	1650–1663	NUM
aji-171	630	8	.	.	PUNCT
aji-171	631	1	wilkins	wilkins	PROPN
aji-171	631	2	,	,	PUNCT
aji-171	631	3	j.	j.	PROPN
aji-171	631	4	m.	m.	PROPN
aji-171	631	5	,	,	PUNCT
aji-171	631	6	&	&	CCONJ
aji-171	631	7	trushina	trushina	PROPN
aji-171	631	8	,	,	PUNCT
aji-171	631	9	e.	e.	PROPN
aji-171	631	10	(	(	PUNCT
aji-171	631	11	2018	2018	NUM
aji-171	631	12	)	)	PUNCT
aji-171	631	13	.	.	PUNCT
aji-171	632	1	application	application	NOUN
aji-171	632	2	of	of	ADP
aji-171	632	3	metabolomics	metabolomic	NOUN
aji-171	632	4	in	in	ADP
aji-171	632	5	alzheimer	alzheimer	PROPN
aji-171	632	6	’s	’s	PART
aji-171	632	7	disease	disease	NOUN
aji-171	632	8	.	.	PUNCT
aji-171	633	1	frontiers	frontier	NOUN
aji-171	633	2	in	in	ADP
aji-171	633	3	neurology	neurology	NOUN
aji-171	633	4	,	,	PUNCT
aji-171	633	5	8	8	NUM
aji-171	633	6	,	,	PUNCT
aji-171	633	7	719	719	NUM
aji-171	633	8	.	.	PUNCT
aji-171	634	1	wishart	wishart	PROPN
aji-171	634	2	,	,	PUNCT
aji-171	634	3	d.	d.	PROPN
aji-171	634	4	s.	s.	PROPN
aji-171	634	5	(	(	PUNCT
aji-171	634	6	2019	2019	NUM
aji-171	634	7	)	)	PUNCT
aji-171	634	8	.	.	PUNCT
aji-171	635	1	metabolomics	metabolomic	NOUN
aji-171	635	2	for	for	ADP
aji-171	635	3	investigating	investigate	VERB
aji-171	635	4	physiological	physiological	ADJ
aji-171	635	5	and	and	CCONJ
aji-171	635	6	pathophysiological	pathophysiological	ADJ
aji-171	635	7	processes	process	NOUN
aji-171	635	8	.	.	PUNCT
aji-171	636	1	physiological	physiological	ADJ
aji-171	636	2	reviews	review	NOUN
aji-171	636	3	,	,	PUNCT
aji-171	636	4	99	99	NUM
aji-171	636	5	,	,	PUNCT
aji-171	636	6	1819–1875	1819–1875	NUM
aji-171	636	7	.	.	PUNCT
aji-171	637	1	xiong	xiong	PROPN
aji-171	637	2	,	,	PUNCT
aji-171	637	3	h.	h.	PROPN
aji-171	637	4	,	,	PUNCT
aji-171	637	5	zhang	zhang	PROPN
aji-171	637	6	,	,	PUNCT
aji-171	637	7	a.	a.	PROPN
aji-171	637	8	h.	h.	PROPN
aji-171	637	9	,	,	PUNCT
aji-171	637	10	zhao	zhao	PROPN
aji-171	637	11	,	,	PUNCT
aji-171	637	12	q.	q.	PROPN
aji-171	637	13	q.	q.	PROPN
aji-171	637	14	,	,	PUNCT
aji-171	637	15	yan	yan	PROPN
aji-171	637	16	,	,	PUNCT
aji-171	637	17	g.	g.	PROPN
aji-171	637	18	l.	l.	PROPN
aji-171	637	19	,	,	PUNCT
aji-171	637	20	sun	sun	PROPN
aji-171	637	21	,	,	PUNCT
aji-171	637	22	h.	h.	PROPN
aji-171	637	23	,	,	PUNCT
aji-171	637	24	&	&	CCONJ
aji-171	637	25	wang	wang	PROPN
aji-171	637	26	,	,	PUNCT
aji-171	637	27	x.	x.	PROPN
aji-171	637	28	j.	j.	PROPN
aji-171	637	29	(	(	PUNCT
aji-171	637	30	2020	2020	NUM
aji-171	637	31	)	)	PUNCT
aji-171	637	32	.	.	PUNCT
aji-171	638	1	discovery	discovery	NOUN
aji-171	638	2	of	of	ADP
aji-171	638	3	quality	quality	NOUN
aji-171	638	4	marker	marker	NOUN
aji-171	638	5	ingredients	ingredient	NOUN
aji-171	638	6	of	of	ADP
aji-171	638	7	panax	panax	PROPN
aji-171	638	8	quinquefolius	quinquefolius	PROPN
aji-171	638	9	driven	drive	VERB
aji-171	638	10	by	by	ADP
aji-171	638	11	high	high	ADJ
aji-171	638	12	-	-	PUNCT
aji-171	638	13	throughput	throughput	NOUN
aji-171	638	14	chinmedomics	chinmedomic	NOUN
aji-171	638	15	approach	approach	NOUN
aji-171	638	16	.	.	PUNCT
aji-171	639	1	phytomedicine	phytomedicine	NOUN
aji-171	639	2	,	,	PUNCT
aji-171	639	3	1(74	1(74	NUM
aji-171	639	4	)	)	PUNCT
aji-171	639	5	,	,	PUNCT
aji-171	639	6	152928	152928	NUM
aji-171	639	7	.	.	PUNCT
aji-171	640	1	xu	xu	INTJ
aji-171	640	2	,	,	PUNCT
aji-171	640	3	y.	y.	PROPN
aji-171	640	4	,	,	PUNCT
aji-171	640	5	chen	chen	PROPN
aji-171	640	6	,	,	PUNCT
aji-171	640	7	s.	s.	PROPN
aji-171	640	8	,	,	PUNCT
aji-171	640	9	&	&	CCONJ
aji-171	640	10	liu	liu	PROPN
aji-171	640	11	,	,	PUNCT
aji-171	640	12	j.	j.	PROPN
aji-171	640	13	(	(	PUNCT
aji-171	640	14	2024	2024	NUM
aji-171	640	15	)	)	PUNCT
aji-171	640	16	.	.	PUNCT
aji-171	641	1	hydrogen	hydrogen	NOUN
aji-171	641	2	sulfide	sulfide	NOUN
aji-171	641	3	derived	derive	VERB
aji-171	641	4	from	from	ADP
aji-171	641	5	apoptotic	apoptotic	ADJ
aji-171	641	6	cells	cell	NOUN
aji-171	641	7	supports	support	VERB
aji-171	641	8	immune	immune	ADJ
aji-171	641	9	homeostasis	homeostasis	NOUN
aji-171	641	10	.	.	PUNCT
aji-171	642	1	metabolism	metabolism	NOUN
aji-171	642	2	open	open	ADJ
aji-171	642	3	,	,	PUNCT
aji-171	642	4	100276	100276	NUM
aji-171	642	5	.	.	PUNCT
aji-171	643	1	xu	xu	INTJ
aji-171	643	2	,	,	PUNCT
aji-171	643	3	y.	y.	PROPN
aji-171	643	4	,	,	PUNCT
aji-171	643	5	jiang	jiang	PROPN
aji-171	643	6	,	,	PUNCT
aji-171	643	7	k.	k.	PROPN
aji-171	643	8	,	,	PUNCT
aji-171	643	9	su	su	PROPN
aji-171	643	10	,	,	PUNCT
aji-171	643	11	f.	f.	PROPN
aji-171	643	12	,	,	PUNCT
aji-171	643	13	deng	deng	PROPN
aji-171	643	14	,	,	PUNCT
aji-171	643	15	r.	r.	PROPN
aji-171	643	16	,	,	PUNCT
aji-171	643	17	cheng	cheng	PROPN
aji-171	643	18	,	,	PUNCT
aji-171	643	19	z.	z.	PROPN
aji-171	643	20	,	,	PUNCT
aji-171	643	21	&	&	CCONJ
aji-171	643	22	wang	wang	PROPN
aji-171	643	23	,	,	PUNCT
aji-171	643	24	d.	d.	PROPN
aji-171	643	25	(	(	PUNCT
aji-171	643	26	2023	2023	NUM
aji-171	643	27	)	)	PUNCT
aji-171	643	28	.	.	PUNCT
aji-171	644	1	a	a	DET
aji-171	644	2	transient	transient	ADJ
aji-171	644	3	wave	wave	NOUN
aji-171	644	4	of	of	ADP
aji-171	644	5	bhlhe41	bhlhe41	NOUN
aji-171	644	6	+	+	CCONJ
aji-171	644	7	resident	resident	ADJ
aji-171	644	8	macrophages	macrophage	NOUN
aji-171	644	9	enables	enable	VERB
aji-171	644	10	remodeling	remodeling	NOUN
aji-171	644	11	of	of	ADP
aji-171	644	12	the	the	DET
aji-171	644	13	developing	develop	VERB
aji-171	644	14	infarcted	infarcte	VERB
aji-171	644	15	myocardium	myocardium	NOUN
aji-171	644	16	.	.	PUNCT
aji-171	645	1	cell	cell	NOUN
aji-171	645	2	reports	report	NOUN
aji-171	645	3	,	,	PUNCT
aji-171	645	4	42	42	NUM
aji-171	645	5	,	,	PUNCT
aji-171	645	6	113174	113174	NUM
aji-171	645	7	.	.	PUNCT
aji-171	646	1	yang	yang	PROPN
aji-171	646	2	,	,	PUNCT
aji-171	646	3	j.	j.	PROPN
aji-171	646	4	,	,	PUNCT
aji-171	646	5	hamade	hamade	NOUN
aji-171	646	6	,	,	PUNCT
aji-171	646	7	m.	m.	NOUN
aji-171	646	8	,	,	PUNCT
aji-171	646	9	wu	wu	PROPN
aji-171	646	10	,	,	PUNCT
aji-171	646	11	q.	q.	PROPN
aji-171	646	12	,	,	PUNCT
aji-171	646	13	wang	wang	PROPN
aji-171	646	14	,	,	PUNCT
aji-171	646	15	q.	q.	PROPN
aji-171	646	16	,	,	PUNCT
aji-171	646	17	axtell	axtell	PROPN
aji-171	646	18	,	,	PUNCT
aji-171	646	19	r.	r.	PROPN
aji-171	646	20	,	,	PUNCT
aji-171	646	21	giri	giri	PROPN
aji-171	646	22	,	,	PUNCT
aji-171	646	23	s.	s.	PROPN
aji-171	646	24	,	,	PUNCT
aji-171	646	25	&	&	CCONJ
aji-171	646	26	mao	mao	PROPN
aji-171	646	27	-	-	PUNCT
aji-171	646	28	draayer	draayer	PROPN
aji-171	646	29	,	,	PUNCT
aji-171	646	30	y.	y.	PROPN
aji-171	646	31	(	(	PUNCT
aji-171	646	32	2022	2022	NUM
aji-171	646	33	)	)	PUNCT
aji-171	646	34	.	.	PUNCT
aji-171	647	1	current	current	ADJ
aji-171	647	2	and	and	CCONJ
aji-171	647	3	future	future	ADJ
aji-171	647	4	biomarkers	biomarker	NOUN
aji-171	647	5	in	in	ADP
aji-171	647	6	multiple	multiple	ADJ
aji-171	647	7	sclerosis	sclerosis	NOUN
aji-171	647	8	.	.	PUNCT
aji-171	648	1	international	international	ADJ
aji-171	648	2	journal	journal	NOUN
aji-171	648	3	of	of	ADP
aji-171	648	4	molecular	molecular	ADJ
aji-171	648	5	sciences	science	NOUN
aji-171	648	6	,	,	PUNCT
aji-171	648	7	23	23	NUM
aji-171	648	8	,	,	PUNCT
aji-171	648	9	5877	5877	NUM
aji-171	648	10	.	.	PUNCT
aji-171	649	1	mamman	mamman	NOUN
aji-171	649	2	et	et	PROPN
aji-171	649	3	al	al	PROPN
aji-171	649	4	.	.	PROPN
aji-171	649	5	;	;	PUNCT
aji-171	649	6	asian	asian	PROPN
aji-171	649	7	j.	j.	PROPN
aji-171	649	8	immunol	immunol	PROPN
aji-171	649	9	.	.	PROPN
aji-171	649	10	,	,	PUNCT
aji-171	649	11	vol	vol	NOUN
aji-171	649	12	.	.	PROPN
aji-171	649	13	8	8	NUM
aji-171	649	14	,	,	PUNCT
aji-171	649	15	no	no	INTJ
aji-171	649	16	.	.	NOUN
aji-171	649	17	1	1	NUM
aji-171	649	18	,	,	PUNCT
aji-171	649	19	pp	pp	ADJ
aji-171	649	20	.	.	PUNCT
aji-171	650	1	190	190	NUM
aji-171	650	2	-	-	SYM
aji-171	650	3	206	206	NUM
aji-171	650	4	,	,	PUNCT
aji-171	650	5	2025	2025	NUM
aji-171	650	6	;	;	PUNCT
aji-171	650	7	article	article	NOUN
aji-171	650	8	no.aji.140476	no.aji.140476	PART
aji-171	650	9	206	206	NUM
aji-171	650	10	yong	yong	PROPN
aji-171	650	11	,	,	PUNCT
aji-171	650	12	c.	c.	PROPN
aji-171	650	13	,	,	PUNCT
aji-171	650	14	stewart	stewart	PROPN
aji-171	650	15	,	,	PUNCT
aji-171	650	16	g.	g.	PROPN
aji-171	650	17	d.	d.	PROPN
aji-171	650	18	,	,	PUNCT
aji-171	650	19	&	&	CCONJ
aji-171	650	20	frezza	frezza	PROPN
aji-171	650	21	,	,	PUNCT
aji-171	650	22	c.	c.	PROPN
aji-171	650	23	(	(	PUNCT
aji-171	650	24	2020	2020	NUM
aji-171	650	25	)	)	PUNCT
aji-171	650	26	.	.	PUNCT
aji-171	651	1	oncometabolites	oncometabolite	NOUN
aji-171	651	2	in	in	ADP
aji-171	651	3	renal	renal	ADJ
aji-171	651	4	cancer	cancer	NOUN
aji-171	651	5	.	.	PUNCT
aji-171	652	1	nature	nature	NOUN
aji-171	652	2	reviews	review	VERB
aji-171	652	3	nephrology	nephrology	NOUN
aji-171	652	4	,	,	PUNCT
aji-171	652	5	16	16	NUM
aji-171	652	6	,	,	PUNCT
aji-171	652	7	156	156	NUM
aji-171	652	8	–	–	PUNCT
aji-171	652	9	172	172	NUM
aji-171	652	10	.	.	X
aji-171	653	1	zhang	zhang	PROPN
aji-171	653	2	,	,	PUNCT
aji-171	653	3	f.	f.	PROPN
aji-171	653	4	,	,	PUNCT
aji-171	653	5	rakhimbekova	rakhimbekova	PROPN
aji-171	653	6	,	,	PUNCT
aji-171	653	7	a.	a.	NOUN
aji-171	653	8	,	,	PUNCT
aji-171	653	9	lashley	lashley	NOUN
aji-171	653	10	,	,	PUNCT
aji-171	653	11	t.	t.	PROPN
aji-171	653	12	,	,	PUNCT
aji-171	653	13	&	&	CCONJ
aji-171	653	14	madl	madl	NOUN
aji-171	653	15	,	,	PUNCT
aji-171	653	16	t.	t.	PROPN
aji-171	653	17	(	(	PUNCT
aji-171	653	18	2023	2023	NUM
aji-171	653	19	)	)	PUNCT
aji-171	653	20	.	.	PUNCT
aji-171	654	1	brain	brain	NOUN
aji-171	654	2	regions	region	NOUN
aji-171	654	3	show	show	VERB
aji-171	654	4	different	different	ADJ
aji-171	654	5	metabolic	metabolic	NOUN
aji-171	654	6	and	and	CCONJ
aji-171	654	7	protein	protein	NOUN
aji-171	654	8	arginine	arginine	NOUN
aji-171	654	9	methylation	methylation	NOUN
aji-171	654	10	phenotypes	phenotype	NOUN
aji-171	654	11	in	in	ADP
aji-171	654	12	frontotemporal	frontotemporal	ADJ
aji-171	654	13	dementias	dementia	NOUN
aji-171	654	14	and	and	CCONJ
aji-171	654	15	alzheimer	alzheimer	PROPN
aji-171	654	16	’s	’s	PART
aji-171	654	17	disease	disease	NOUN
aji-171	654	18	.	.	PUNCT
aji-171	655	1	progress	progress	NOUN
aji-171	655	2	in	in	ADP
aji-171	655	3	neurobiology	neurobiology	NOUN
aji-171	655	4	,	,	PUNCT
aji-171	655	5	221	221	NUM
aji-171	655	6	,	,	PUNCT
aji-171	655	7	102400	102400	NUM
aji-171	655	8	.	.	PUNCT
aji-171	656	1	zhang	zhang	PROPN
aji-171	656	2	,	,	PUNCT
aji-171	656	3	h.	h.	PROPN
aji-171	656	4	l.	l.	PROPN
aji-171	656	5	,	,	PUNCT
aji-171	656	6	zhang	zhang	PROPN
aji-171	656	7	,	,	PUNCT
aji-171	656	8	a.	a.	PROPN
aji-171	656	9	h.	h.	PROPN
aji-171	656	10	,	,	PUNCT
aji-171	656	11	miao	miao	PROPN
aji-171	656	12	,	,	PUNCT
aji-171	656	13	j.	j.	PROPN
aji-171	656	14	h.	h.	PROPN
aji-171	656	15	,	,	PUNCT
aji-171	656	16	sun	sun	PROPN
aji-171	656	17	,	,	PUNCT
aji-171	656	18	h.	h.	PROPN
aji-171	656	19	,	,	PUNCT
aji-171	656	20	yan	yan	PROPN
aji-171	656	21	,	,	PUNCT
aji-171	656	22	g.	g.	PROPN
aji-171	656	23	l.	l.	PROPN
aji-171	656	24	,	,	PUNCT
aji-171	656	25	&	&	CCONJ
aji-171	656	26	wu	wu	PROPN
aji-171	656	27	,	,	PUNCT
aji-171	656	28	f.	f.	PROPN
aji-171	656	29	f.	f.	PROPN
aji-171	656	30	(	(	PUNCT
aji-171	656	31	2019	2019	NUM
aji-171	656	32	)	)	PUNCT
aji-171	656	33	.	.	PUNCT
aji-171	657	1	targeting	target	VERB
aji-171	657	2	regulation	regulation	NOUN
aji-171	657	3	of	of	ADP
aji-171	657	4	tryptophan	tryptophan	NOUN
aji-171	657	5	metabolism	metabolism	NOUN
aji-171	657	6	for	for	ADP
aji-171	657	7	colorectal	colorectal	ADJ
aji-171	657	8	cancer	cancer	NOUN
aji-171	657	9	therapy	therapy	NOUN
aji-171	657	10	:	:	PUNCT
aji-171	657	11	a	a	DET
aji-171	657	12	systematic	systematic	ADJ
aji-171	657	13	review	review	NOUN
aji-171	657	14	.	.	PUNCT
aji-171	658	1	rsc	rsc	PROPN
aji-171	658	2	advances	advance	NOUN
aji-171	658	3	,	,	PUNCT
aji-171	658	4	9(6	9(6	NUM
aji-171	658	5	)	)	PUNCT
aji-171	658	6	,	,	PUNCT
aji-171	658	7	3072	3072	NUM
aji-171	658	8	–	–	PUNCT
aji-171	658	9	3080	3080	NUM
aji-171	658	10	.	.	PUNCT
aji-171	659	1	zhang	zhang	PROPN
aji-171	659	2	,	,	PUNCT
aji-171	659	3	y.	y.	PROPN
aji-171	659	4	,	,	PUNCT
aji-171	659	5	chen	chen	PROPN
aji-171	659	6	,	,	PUNCT
aji-171	659	7	s.	s.	PROPN
aji-171	659	8	,	,	PUNCT
aji-171	659	9	&	&	CCONJ
aji-171	659	10	liu	liu	PROPN
aji-171	659	11	,	,	PUNCT
aji-171	659	12	j.	j.	PROPN
aji-171	659	13	(	(	PUNCT
aji-171	659	14	2023	2023	NUM
aji-171	659	15	)	)	PUNCT
aji-171	659	16	.	.	PUNCT
aji-171	660	1	mitochondrion	mitochondrion	NOUN
aji-171	660	2	quality	quality	NOUN
aji-171	660	3	control	control	NOUN
aji-171	660	4	for	for	ADP
aji-171	660	5	longevity	longevity	NOUN
aji-171	660	6	promotion	promotion	NOUN
aji-171	660	7	.	.	PUNCT
aji-171	661	1	metabolism	metabolism	NOUN
aji-171	661	2	open	open	ADJ
aji-171	661	3	,	,	PUNCT
aji-171	661	4	100259	100259	NUM
aji-171	661	5	.	.	PUNCT
aji-171	662	1	zhao	zhao	PROPN
aji-171	662	2	,	,	PUNCT
aji-171	662	3	g.	g.	PROPN
aji-171	662	4	,	,	PUNCT
aji-171	662	5	he	he	PRON
aji-171	662	6	,	,	PUNCT
aji-171	662	7	f.	f.	PROPN
aji-171	662	8	,	,	PUNCT
aji-171	662	9	wu	wu	PROPN
aji-171	662	10	,	,	PUNCT
aji-171	662	11	c.	c.	PROPN
aji-171	662	12	,	,	PUNCT
aji-171	662	13	li	li	PROPN
aji-171	662	14	,	,	PUNCT
aji-171	662	15	p.	p.	PROPN
aji-171	662	16	,	,	PUNCT
aji-171	662	17	li	li	PROPN
aji-171	662	18	,	,	PUNCT
aji-171	662	19	n.	n.	PROPN
aji-171	662	20	,	,	PUNCT
aji-171	662	21	deng	deng	PROPN
aji-171	662	22	,	,	PUNCT
aji-171	662	23	j.	j.	PROPN
aji-171	662	24	,	,	PUNCT
aji-171	662	25	zhu	zhu	PROPN
aji-171	662	26	,	,	PUNCT
aji-171	662	27	g.	g.	PROPN
aji-171	662	28	,	,	PUNCT
aji-171	662	29	ren	ren	PROPN
aji-171	662	30	,	,	PUNCT
aji-171	662	31	w.	w.	PROPN
aji-171	662	32	,	,	PUNCT
aji-171	662	33	&	&	CCONJ
aji-171	662	34	peng	peng	PROPN
aji-171	662	35	,	,	PUNCT
aji-171	662	36	y.	y.	PROPN
aji-171	662	37	(	(	PUNCT
aji-171	662	38	2018	2018	NUM
aji-171	662	39	)	)	PUNCT
aji-171	662	40	.	.	PUNCT
aji-171	663	1	betaine	betaine	NOUN
aji-171	663	2	in	in	ADP
aji-171	663	3	inflammation	inflammation	NOUN
aji-171	663	4	:	:	PUNCT
aji-171	663	5	mechanistic	mechanistic	ADJ
aji-171	663	6	aspects	aspect	NOUN
aji-171	663	7	and	and	CCONJ
aji-171	663	8	applications	application	NOUN
aji-171	663	9	.	.	PUNCT
aji-171	664	1	frontiers	frontier	NOUN
aji-171	664	2	in	in	ADP
aji-171	664	3	immunology	immunology	NOUN
aji-171	664	4	,	,	PUNCT
aji-171	664	5	9	9	NUM
aji-171	664	6	,	,	PUNCT
aji-171	664	7	1070	1070	NUM
aji-171	664	8	.	.	PUNCT
aji-171	665	1	zhou	zhou	PROPN
aji-171	665	2	,	,	PUNCT
aji-171	665	3	j.	j.	PROPN
aji-171	665	4	,	,	PUNCT
aji-171	665	5	&	&	CCONJ
aji-171	665	6	zhong	zhong	PROPN
aji-171	665	7	,	,	PUNCT
aji-171	665	8	l.	l.	PROPN
aji-171	665	9	(	(	PUNCT
aji-171	665	10	2022	2022	NUM
aji-171	665	11	)	)	PUNCT
aji-171	665	12	.	.	PUNCT
aji-171	666	1	applications	application	NOUN
aji-171	666	2	of	of	ADP
aji-171	666	3	liquid	liquid	ADJ
aji-171	666	4	chromatography	chromatography	NOUN
aji-171	666	5	-	-	PUNCT
aji-171	666	6	mass	mass	NOUN
aji-171	666	7	spectrometry	spectrometry	NOUN
aji-171	666	8	based	base	VERB
aji-171	666	9	metabolomics	metabolomic	NOUN
aji-171	666	10	in	in	ADP
aji-171	666	11	predictive	predictive	ADJ
aji-171	666	12	and	and	CCONJ
aji-171	666	13	personalized	personalized	ADJ
aji-171	666	14	medicine	medicine	NOUN
aji-171	666	15	.	.	PUNCT
aji-171	667	1	frontiers	frontier	NOUN
aji-171	667	2	in	in	ADP
aji-171	667	3	molecular	molecular	ADJ
aji-171	667	4	biosciences	bioscience	NOUN
aji-171	667	5	,	,	PUNCT
aji-171	667	6	9	9	NUM
aji-171	667	7	,	,	PUNCT
aji-171	667	8	1049016	1049016	NUM
aji-171	667	9	.	.	PUNCT
aji-171	668	1	zhou	zhou	PROPN
aji-171	668	2	,	,	PUNCT
aji-171	668	3	p.	p.	PROPN
aji-171	668	4	,	,	PUNCT
aji-171	668	5	chen	chen	PROPN
aji-171	668	6	,	,	PUNCT
aji-171	668	7	s.	s.	PROPN
aji-171	668	8	,	,	PUNCT
aji-171	668	9	&	&	CCONJ
aji-171	668	10	liu	liu	PROPN
aji-171	668	11	,	,	PUNCT
aji-171	668	12	l.	l.	PROPN
aji-171	668	13	(	(	PUNCT
aji-171	668	14	2024	2024	NUM
aji-171	668	15	)	)	PUNCT
aji-171	668	16	.	.	PUNCT
aji-171	669	1	temporal	temporal	ADJ
aji-171	669	2	and	and	CCONJ
aji-171	669	3	spatial	spatial	ADJ
aji-171	669	4	dynamics	dynamic	NOUN
aji-171	669	5	of	of	ADP
aji-171	669	6	immune	immune	ADJ
aji-171	669	7	response	response	NOUN
aji-171	669	8	post	post	VERB
aji-171	669	9	myocardial	myocardial	ADJ
aji-171	669	10	infarction	infarction	NOUN
aji-171	669	11	.	.	PUNCT
aji-171	670	1	metabolism	metabolism	NOUN
aji-171	670	2	open	open	ADJ
aji-171	670	3	,	,	PUNCT
aji-171	670	4	100273	100273	NUM
aji-171	670	5	.	.	PUNCT
aji-171	671	1	zhu	zhu	PROPN
aji-171	671	2	,	,	PUNCT
aji-171	671	3	y.	y.	PROPN
aji-171	671	4	,	,	PUNCT
aji-171	671	5	li	li	PROPN
aji-171	671	6	,	,	PUNCT
aji-171	671	7	q.	q.	PROPN
aji-171	671	8	,	,	PUNCT
aji-171	671	9	&	&	CCONJ
aji-171	671	10	jiang	jiang	PROPN
aji-171	671	11	,	,	PUNCT
aji-171	671	12	h.	h.	PROPN
aji-171	671	13	(	(	PUNCT
aji-171	671	14	2020	2020	NUM
aji-171	671	15	)	)	PUNCT
aji-171	671	16	.	.	PUNCT
aji-171	672	1	gut	gut	VERB
aji-171	672	2	microbiota	microbiota	NOUN
aji-171	672	3	in	in	ADP
aji-171	672	4	atherosclerosis	atherosclerosis	NOUN
aji-171	672	5	:	:	PUNCT
aji-171	672	6	focus	focus	VERB
aji-171	672	7	on	on	ADP
aji-171	672	8	trimethylamine	trimethylamine	NOUN
aji-171	672	9	n	n	CCONJ
aji-171	672	10	-	-	PUNCT
aji-171	672	11	oxide	oxide	NOUN
aji-171	672	12	.	.	PUNCT
aji-171	673	1	apmis	apmis	PROPN
aji-171	673	2	–	–	PUNCT
aji-171	673	3	all	all	DET
aji-171	673	4	purpose	purpose	NOUN
aji-171	673	5	medical	medical	ADJ
aji-171	673	6	information	information	NOUN
aji-171	673	7	system	system	NOUN
aji-171	673	8	,	,	PUNCT
aji-171	673	9	128	128	NUM
aji-171	673	10	,	,	PUNCT
aji-171	673	11	353–366	353–366	NUM
aji-171	673	12	.	.	PUNCT
aji-171	674	1	disclaimer	disclaimer	ADJ
aji-171	674	2	/	/	SYM
aji-171	674	3	publisher	publisher	NOUN
aji-171	674	4	’s	’s	PART
aji-171	674	5	note	note	NOUN
aji-171	674	6	:	:	PUNCT
aji-171	674	7	the	the	DET
aji-171	674	8	statements	statement	NOUN
aji-171	674	9	,	,	PUNCT
aji-171	674	10	opinions	opinion	NOUN
aji-171	674	11	and	and	CCONJ
aji-171	674	12	data	datum	NOUN
aji-171	674	13	contained	contain	VERB
aji-171	674	14	in	in	ADP
aji-171	674	15	all	all	DET
aji-171	674	16	publications	publication	NOUN
aji-171	674	17	are	be	AUX
aji-171	674	18	solely	solely	ADV
aji-171	674	19	those	those	PRON
aji-171	674	20	of	of	ADP
aji-171	674	21	the	the	DET
aji-171	674	22	individual	individual	ADJ
aji-171	674	23	author(s	author(s	PROPN
aji-171	674	24	)	)	PUNCT
aji-171	674	25	and	and	CCONJ
aji-171	674	26	contributor(s	contributor(s	NOUN
aji-171	674	27	)	)	PUNCT
aji-171	674	28	and	and	CCONJ
aji-171	674	29	not	not	PART
aji-171	674	30	of	of	ADP
aji-171	674	31	the	the	DET
aji-171	674	32	publisher	publisher	NOUN
aji-171	674	33	and/or	and/or	CCONJ
aji-171	674	34	the	the	DET
aji-171	674	35	editor(s	editor(s	NOUN
aji-171	674	36	)	)	PUNCT
aji-171	674	37	.	.	PUNCT
aji-171	675	1	this	this	DET
aji-171	675	2	publisher	publisher	NOUN
aji-171	675	3	and/or	and/or	CCONJ
aji-171	675	4	the	the	DET
aji-171	675	5	editor(s	editor(s	NOUN
aji-171	675	6	)	)	PUNCT
aji-171	675	7	disclaim	disclaim	VERB
aji-171	675	8	responsibility	responsibility	NOUN
aji-171	675	9	for	for	ADP
aji-171	675	10	any	any	DET
aji-171	675	11	injury	injury	NOUN
aji-171	675	12	to	to	ADP
aji-171	675	13	people	people	NOUN
aji-171	675	14	or	or	CCONJ
aji-171	675	15	property	property	NOUN
aji-171	675	16	resulting	result	VERB
aji-171	675	17	from	from	ADP
aji-171	675	18	any	any	DET
aji-171	675	19	ideas	idea	NOUN
aji-171	675	20	,	,	PUNCT
aji-171	675	21	methods	method	NOUN
aji-171	675	22	,	,	PUNCT
aji-171	675	23	instructions	instruction	NOUN
aji-171	675	24	or	or	CCONJ
aji-171	675	25	products	product	NOUN
aji-171	675	26	referred	refer	VERB
aji-171	675	27	to	to	ADP
aji-171	675	28	in	in	ADP
aji-171	675	29	the	the	DET
aji-171	675	30	content	content	NOUN
aji-171	675	31	.	.	PUNCT
aji-171	676	1	_	_	PUNCT
aji-171	677	1	_	_	PUNCT
aji-171	678	1	_	_	PUNCT
aji-171	679	1	_	_	PUNCT
aji-171	680	1	_	_	PUNCT
aji-171	681	1	_	_	PUNCT
aji-171	682	1	_	_	PUNCT
aji-171	683	1	_	_	PUNCT
aji-171	684	1	_	_	PUNCT
aji-171	685	1	_	_	PUNCT
aji-171	686	1	_	_	PUNCT
aji-171	687	1	_	_	PUNCT
aji-171	688	1	_	_	PUNCT
aji-171	689	1	_	_	PUNCT
aji-171	690	1	_	_	PUNCT
aji-171	691	1	_	_	PUNCT
aji-171	692	1	_	_	PUNCT
aji-171	693	1	_	_	PUNCT
aji-171	694	1	_	_	PUNCT
aji-171	695	1	_	_	PUNCT
aji-171	696	1	_	_	PUNCT
aji-171	697	1	_	_	PUNCT
aji-171	698	1	_	_	PUNCT
aji-171	699	1	_	_	PUNCT
aji-171	700	1	_	_	PUNCT
aji-171	701	1	_	_	PUNCT
aji-171	702	1	_	_	PUNCT
aji-171	703	1	_	_	PUNCT
aji-171	704	1	_	_	PUNCT
aji-171	705	1	_	_	PUNCT
aji-171	706	1	_	_	PUNCT
aji-171	707	1	_	_	PUNCT
aji-171	708	1	_	_	PUNCT
aji-171	709	1	_	_	PUNCT
aji-171	710	1	_	_	PUNCT
aji-171	711	1	_	_	PUNCT
aji-171	712	1	_	_	PUNCT
aji-171	713	1	_	_	PUNCT
aji-171	714	1	_	_	PUNCT
aji-171	715	1	_	_	PUNCT
aji-171	716	1	_	_	PUNCT
aji-171	717	1	_	_	PUNCT
aji-171	718	1	_	_	PUNCT
aji-171	719	1	_	_	PUNCT
aji-171	720	1	_	_	PUNCT
aji-171	721	1	_	_	PUNCT
aji-171	722	1	_	_	PUNCT
aji-171	723	1	_	_	PUNCT
aji-171	724	1	_	_	PUNCT
aji-171	725	1	_	_	PUNCT
aji-171	726	1	_	_	PUNCT
aji-171	727	1	_	_	PUNCT
aji-171	728	1	_	_	PUNCT
aji-171	729	1	_	_	PUNCT
aji-171	730	1	_	_	PUNCT
aji-171	731	1	_	_	PUNCT
aji-171	732	1	_	_	PUNCT
aji-171	733	1	_	_	PUNCT
aji-171	734	1	_	_	PUNCT
aji-171	735	1	_	_	PUNCT
aji-171	736	1	_	_	PUNCT
aji-171	737	1	_	_	PUNCT
aji-171	738	1	_	_	PUNCT
aji-171	739	1	_	_	PUNCT
aji-171	740	1	_	_	PUNCT
aji-171	741	1	_	_	PUNCT
aji-171	742	1	_	_	PUNCT
aji-171	743	1	_	_	PUNCT
aji-171	744	1	_	_	PUNCT
aji-171	745	1	_	_	PUNCT
aji-171	746	1	_	_	PUNCT
aji-171	747	1	_	_	PUNCT
aji-171	748	1	_	_	PUNCT
aji-171	749	1	_	_	PUNCT
aji-171	750	1	_	_	PUNCT
aji-171	751	1	_	_	PUNCT
aji-171	752	1	_	_	PUNCT
aji-171	753	1	_	_	PUNCT
aji-171	754	1	_	_	PUNCT
aji-171	755	1	_	_	PUNCT
aji-171	756	1	_	_	PUNCT
aji-171	757	1	©	©	PRON
aji-171	757	2	copyright	copyright	NOUN
aji-171	757	3	(	(	PUNCT
aji-171	757	4	2025	2025	NUM
aji-171	757	5	):	):	PUNCT
aji-171	757	6	author(s	author(s	NOUN
aji-171	757	7	)	)	PUNCT
aji-171	757	8	.	.	PUNCT
aji-171	758	1	the	the	DET
aji-171	758	2	licensee	licensee	NOUN
aji-171	758	3	is	be	AUX
aji-171	758	4	the	the	DET
aji-171	758	5	journal	journal	PROPN
aji-171	758	6	publisher	publisher	NOUN
aji-171	758	7	.	.	PUNCT
aji-171	759	1	this	this	PRON
aji-171	759	2	is	be	AUX
aji-171	759	3	an	an	DET
aji-171	759	4	open	open	ADJ
aji-171	759	5	access	access	NOUN
aji-171	759	6	article	article	NOUN
aji-171	759	7	distributed	distribute	VERB
aji-171	759	8	under	under	ADP
aji-171	759	9	the	the	DET
aji-171	759	10	terms	term	NOUN
aji-171	759	11	of	of	ADP
aji-171	759	12	the	the	DET
aji-171	759	13	creative	creative	ADJ
aji-171	759	14	commons	common	NOUN
aji-171	759	15	attribution	attribution	NOUN
aji-171	759	16	license	license	NOUN
aji-171	759	17	(	(	PUNCT
aji-171	759	18	http://creativecommons.org/licenses/by/4.0	http://creativecommons.org/licenses/by/4.0	NOUN
aji-171	759	19	)	)	PUNCT
aji-171	759	20	,	,	PUNCT
aji-171	759	21	which	which	PRON
aji-171	759	22	permits	permit	VERB
aji-171	759	23	unrestricted	unrestricted	ADJ
aji-171	759	24	use	use	NOUN
aji-171	759	25	,	,	PUNCT
aji-171	759	26	distribution	distribution	NOUN
aji-171	759	27	,	,	PUNCT
aji-171	759	28	and	and	CCONJ
aji-171	759	29	reproduction	reproduction	NOUN
aji-171	759	30	in	in	ADP
aji-171	759	31	any	any	DET
aji-171	759	32	medium	medium	NOUN
aji-171	759	33	,	,	PUNCT
aji-171	759	34	provided	provide	VERB
aji-171	759	35	the	the	DET
aji-171	759	36	original	original	ADJ
aji-171	759	37	work	work	NOUN
aji-171	759	38	is	be	AUX
aji-171	759	39	properly	properly	ADV
aji-171	759	40	cited	cite	VERB
aji-171	759	41	.	.	PUNCT
aji-171	760	1	peer	peer	NOUN
aji-171	760	2	-	-	PUNCT
aji-171	760	3	review	review	NOUN
aji-171	760	4	history	history	NOUN
aji-171	760	5	:	:	PUNCT
aji-171	760	6	the	the	DET
aji-171	760	7	peer	peer	NOUN
aji-171	760	8	review	review	NOUN
aji-171	760	9	history	history	NOUN
aji-171	760	10	for	for	ADP
aji-171	760	11	this	this	DET
aji-171	760	12	paper	paper	NOUN
aji-171	760	13	can	can	AUX
aji-171	760	14	be	be	AUX
aji-171	760	15	accessed	access	VERB
aji-171	760	16	here	here	ADV
aji-171	760	17	:	:	PUNCT
aji-171	760	18	https://pr.sdiarticle5.com/review-history/140476	https://pr.sdiarticle5.com/review-history/140476	X
aji-171	760	19	https://pr.sdiarticle5.com/review-history/140476	https://pr.sdiarticle5.com/review-history/140476	NOUN